bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnostic Performance of Standard and Inverted Grey-Scale CXR in Detection
of Lung Lesions in COVID-19 Patients: A Single Institute Study in the Region of
Abu Dhabi
Authors: Al Helali Abeer A. , Kukkady Mohamed A. , Saeed Ghufran A. , Elholiby Tamer I. , Al Mansoori Rabab A. , Ahmed Luai A. 
Published: December 2021

Purpose:
This study aimed at evaluating the diagnostic performance of standard greyscale and inverted greyscale Chest X-ray (CXR) using Computed
Tomography (CT) scan as a gold standard.

Methods:
In this retrospective study, electronic medical records of 120 patients who had valid CXR and High-resolution CT (HRCT) within less than 24
hours after having a positive COVID-19 RT-PCR test during the period from May 19th to May 23rd, 2020, in a single tertiary care center were
reviewed.

PA chest radiographs were presented on 2 occasions to 5 radiologists to evaluate the role and appropriateness of standard greyscale and inverted
greyscale chest radiographs (CXR) when images are viewed on high-specification viewing systems using a primary display monitor and compared
to computed tomography (CT) findings for screening and management of suspected or confirmed COVID-19 patients.

Results:
Ninety-six (80%) patients had positive CT findings, 81 (67.5%) had positive grey scale CXR lesions, and 25 (20.8%) had better detection in the
inverted grey scale CXR. The CXR sensitivity for COVID-19 pneumonia was 93.8% (95% CI (86.2% - 98.0%) and the specificity was 48.7%
(95% CI (32.4% - 65.2%). The CXR sensitivity of detecting lung lesions was slightly higher in male (95.1% (95% CI (86.3% - 99.0%)) than
female (90.0% (95% CI (68.3% - 98.8%)), while the specificity was 48.0% (95% CI (27.8% - 68.7%) and 50.0% (95% CI (23.0% - 77.0%) in
males and females, respectively. However, no significant difference was detected in ROC area between men and women.

Conclusion:
The sensitivity of detecting lung lesions of CXR was relatively high, particularly in men. The results of the study support the idea of considering
conventional radiographs as an important diagnostic tool in suspected COVID-19 patients, especially in healthcare facilities where there is no
access to HRCT scans.
CXR shows high sensitivity for detecting lung lesions in HRCT confirmed COVID-19 patients. Better detection of lesions was noted in the
inverted greyscale CXR in 20.8% of cases, with positive findings in standard greyscale CXR.
Conventional radiographs can be used as diagnostic tools in suspected COVID-19 patients, especially in healthcare facilities where there is no
access to HRCT scans.
Celastrus orbiculatus Extract Inhibits the Epithelial-Mesenchymal Transition Process
by Transforming Growth Factor-β Signaling Pathway in Gastric Cancer
Authors: Wang Haibo , Zhang Xiaochun , Liu Yanqing , Chu Zewen , Ou Shiya , Ni Tengyang , Dai Xiaojun 
Published: December 2021

Background:
Gastric cancer is the fifth most common tumor and has the third-highest mortality rate among
various malignant tumors, and the survival rate of patients is low. Celastrus orbiculatus extract (COE) has been shown
to inhibit the activity of a variety of tumors. In this study, we examined the inhibition of the epithelial-mesenchymal
transition (EMT) process in gastric cancer cells by COE through the transforming growth factor-β (TGF-β) signaling
pathway.

Methods:
COE was first diluted to various concentrations and then used to treat SGC-7901, BGC-823, MGC-803, and
AGS cells. Cell proliferation was assessed by an MTT (thiazole blue) assay. Transwell assays were used to assess cell
invasion and migration. The high-content imaging technology was used to further observe the effects of the drug on
cell invasion and migration. Western blotting was used to assess the effects of the drug on the expression of EMT and
Smad2/3 signaling pathway-related proteins.

Results:
We found that COE inhibited the migration and invasion of AGS gastric cancer cells in a dose-dependent
manner. Consequently, COE decreased the expression of EMT-related proteins and proteins related to the Smad2/3
signaling pathway in gastric cancer cells, inhibiting the migration and invasion of gastric cancer cells, and this effect
occurred through the TGF-β signaling pathway.

Summary:
We investigated that COE could inhibit the proliferation of gastric cancer cells and inhibit invasion and
metastasis by inhibiting the EMT process at the molecular level and its effect on the TGF-β signaling pathway.
Lessons from Ten Years’ the Prevalence of Congenital Rubella Syndrome
(CRS) in the Young Population Living in a Developing Country, Tehran;
Iran
Authors: Noorbakhsh Samileh , Vafaee-Shahi Mohammad , Tahernia Leila , Ashouri Sarvenaz , Riahi Aina 
Published: December 2021

Background:
A safe and effective rubella vaccine is available and prescribed in IRAN.

Objective:
This is a survey of CRS cases collected based on WHO criteria one decade after the MR
vaccination campaign (2003)

Methods:
This Multi-stage prospective/cross-sectional study was carried out in three stages in 3 educational
hospitals in Tehran (Rasoul Aram, Akbar Abadi, and Firoozabadi), In the first stage of the study
between 2011 and 2012 total of 186 infants were evaluated, and in the second stage of the study, total
163 blood samples of infants with suspected INTRA UTERINE INFECTION were compared with a
group of healthy matched infants. In the first and second stages, Rubella immunity (IgG&IgM) in cord
blood was evaluated by the Eliza method.

Results:
Despite MR vaccination in Iran, after one decade"confirmed CRS" and " compatible CRS"
was diagnosed in 5 and 31 from 89 CRS suspected cases.

Conclusion:
The incidence of "confirmed CRS" in every 100 CRS suspected infants (after campaign)
is 5.6 %, and 31 CRS Compatible cases are so important. Without active CRS surveillance, mild infection
such as IUGR, hearing loss, heart abnormalities, impaired vision, and mental retardation even in
the developed country might be missed. Fetal infection is persistent, which imposes additional costs on
the country. Another mass vaccination in women and girls is needed. Also, the anti-rubella IgG testing
before pregnancy in women who were not vaccinated; vaccination of women before marriage
/pregnancy should be obligatory in order to prevent the CRS.
One-Year Remission Rate of Chronic Headache Comparing Video and Face-to-Face Consultations by Neurologist: Randomized Controlled Trial
Authors: Bekkelund Svein Ivar , Müller Kai Ivar 
Published: December 2021

Background
Chronic headache causing severe headache-related disability for those affected by the disease is under- or misdiagnosed in many cases and therefore requires easy access to a specialist for optimal health care management.

Objective
The goal of the research is to determine whether video consultations are noninferior to face-to-face consultations in treating chronic headache patients referred to a specialist in Northern Norway.

Methods
Patients included in the study were recruited from general practice referrals to a specialist at a neurological department in Northern Norway (Tromsø) and diagnosed according to the International Headache Society classification system. In a randomized controlled design, the 1-year remission rate of chronic headache (change from ≥15 to <15 headache days per month during the last 3 months), patient satisfaction with a specialist consultation, and need for follow-up consultations by general practitioners were compared between groups consulted by video and face-to-face in a post hoc analysis. Data were collected by interview (baseline) and questionnaire (follow-up).

Results
From a baseline cohort of 402 headache patients consecutively referred from general practice to a specialist over 2.5 years, 58.0% (233/402) were classified as chronic headache and included in this study. Response rates were 71.7% (86/120) in the video group and 67.3% (76/113) in the face-to-face group. One-year remission from chronic headache was achieved in 43.0% (37/86) in the video group and 39.5% (30/76) in the face-to-face group (P=.38). Patient satisfaction with consultations were 86.5% (32/37; video) and 93.3% (28/30; face-to-face; P=.25). A total of 30% (11/37) in the video group and 53% (16/30) in the face-to-face group consulted general practitioners during the follow-up period (P=.03), and median number of consultations was 1 (IQR 0-13) and 1.5 (IQR 0-15), respectively (P=.19).

Conclusions
One-year remission rate from chronic headache was about 40% regardless of consultation form. Likewise, patient satisfaction with consultation and need for follow-up visits in general practice post consultation was similar. Treating chronic headache patients by using video consultations is not inferior to face-to-face consultations and may be used in clinical neurological practice.

Trial Registration
ClinicalTrials.gov NCT02270177; https://clinicaltrials.gov/ct2/show/NCT02270177
Evaluating the Quality of Asynchronous Versus Synchronous Virtual Care in Patients With Erectile Dysfunction: Retrospective Cohort Study
Authors: Broffman Lauren , Barnes Melynda , Stern Kevin , Westergren Amy 
Published: December 2021

Background
Asynchronous health care encounters are becoming an increasingly mainstream form of telehealth. While synchronous phone or video visits have become more widely accepted, US policymakers and other key health care stakeholders have been hesitant to fully embrace asynchronous diagnosis and treatment. This is particularly true in the context of direct-to-consumer (DTC) platforms, where encounters are patient-initiated and there is no preestablished relationship with a provider. This hesitation is compounded by limited research comparing outcomes between asynchronous and synchronous care, especially in the DTC context.

Objective
The purpose of this study was to explore whether asynchronous care leads to different patient outcomes in the form of medication-related adverse events when compared to synchronous virtual care.

Methods
Using 10,000 randomly sampled patient records from a prominent US-based DTC platform, we analyzed the rates of patient-reported side effects from commonly prescribed erectile dysfunction medications and compared these rates across modalities of treatment.

Results
Asynchronous care resulted in lower but nonsignificant differences in the rates of the reported drug-related side effects compared to synchronous treatment.

Conclusions
In some circumstances, such as treatment for erectile dysfunction, asynchronous care can offer the same level of safety in prescribing when compared to synchronous care. More research is needed to evaluate the safety of asynchronous care across a wider set of conditions and measures.
Subjective Well Being Pada Mahasiswi Tunanetra
Authors: Husin Lauditta Soraya 
Published: December 2021

Abstact Blind students with disabilities not only experience obstacles in the visual process but also have problems in the lecture process and social life including problems of accessibility, social relations, communication, difficulties in the lecture process and the views of the surrounding community. This affects the psychological condition of individuals, especially female students, this happens because women have genetic susceptibility, significant hormonal changes, a tendency to overthink things, and socio-cultural pressure. Alignment between the study process and self-acceptance with limited vision is the main goal that is continuously maintained and achieved by blind students, coupled with various pressures and problems in completing education, will be a challenge and pressure for students with visual impairments that can affect the subjective well-being of individuals ( Subjective Well Being). The purpose of this article is to determine the Subjective Well Being in blind female students and the factors that influence Subjective Well Being in blind female students. The method used is descriptive qualitative case study method. Participants in this study were three blind female students with data collection techniques through in-depth interviews and observations. The results showed that students with visual impairment have a Subjective Well Being in terms of dimensions of self-acceptance, life goals, self-growth, autonomy, environmental control, and positive relationships with others.Keywords: Subjective Well Being, Disabilities, Blind students
Profil Pendidikan Jasmani Olahraga dan Kesehatan di SMP Negeri se-Kecamatan Buleleng
Authors: Wiguna I Gusti Lanang Agung Pratama , Kanca I Nyoman , Spyanawati Ni Luh Putu 
Published: December 2021

Keberhasilan peserta didik dalam mengikuti proses pembelajaran dipengaruhi oleh dua faktor yaitu faktor internal dan eksternal. Di dalam pembelajaran PJOK, faktor internal memiliki peran yang penting dalam keberhasilan proses pembelajaran, karena faktor internal itu berasal dari dalam diri peserta didik. Faktor eksternal juga memberikan dampak yang sangat besar untuk dapat membantu tercapainya keberhasilan proses pembelajaran. Penelitian ini bertujuan untuk memperoleh data empirik tentang profil pendidikan jasmani olahraga dan kesehatan. Penelitian ini menggunakan pendekatan deskriptif kuantitatif dengan teknik survei. Subjek penelitian ini adalah seluruh SMP Negeri yang berada di Kecamatan Buleleng yang berjumlah 8 Sekolah. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah observasi langsung dalam bentuk wawancara dan kuesioner. Instrumen yang digunakan dalam penelitian ini berpedoman pada PDPJOI. Data yang terkumpul kemudian di analisis dengan analisis deskriptif. Berdasarkan hasil analisis menunjukkan bahwa profil pendidikan jasmani olahraga dan kesehatan berada pada kategori cukup. Implikasi penelitian ini agar profil pendidikan PJOK lebih ditingkatkan lagi.
Pembelajaran Daring Berbantuan Paired Storytelling terhadap Hasil Belajar Pengembangan Pembelajaran PKn Mahasiswa PGSD
Authors: Widiastini Ni Wayan Eka , Yudiana I Kadek Edi 
Published: December 2021

Pembelajaran daring juga mempunyai keterbatasan karena metode yang digunakan bersifat monoton sehingga berdanpak terhadap hasil belajar siswa serta berdampak terhadap rendahnya kempuan social mahasiswa. Tujuan penelitian ini adalah mengetahui efektifitas pembelajaran daring berbantuan Paired Storytelling terhadap hasil belajar mahasiswa PGSD. Jenis penelitian yang dilakukan adalah penelitian semu. Rancangan penelitian ini menggunakan rancangan posttest only control group design. Populasi penelitian ini adalah seluruh mahasiswa semester VI PGSD yang ada di Singaraja yang berjumlah 176. Data diperoleh dari hasil perhitungan skor tes hasil belajar mahasiswa. Penelitian ini menggunakan dua teknik analisis yaitu analisis deskriptif dan analisis inferensial.Hasil analisis dengan uji t diperoleh terdapat perbedaan antara mahasiswa yang belajar secara daring berbatuan paired Storytelling dengan mahasiswa yang belajar secara daring. Hal ini dapat dilihat dari nilai sig. yang lebih kecil dari 0,05 yaitu 0,00. Terdapat perbedaan antara mahasiswa yang belajar secara daring berbatuan paired Storytelling dengan mahasiswa yang belajar secara daring.
LITERARY ABILITIES IN DISCURSIVE PRACTICE: A THEORETICAL AND HISTORICAL OVERVIEW
Authors: Корытова Алена Игоревна , Корытова Галина Степановна 
Published: December 2021

Представлен теоретико-исторический обзор исследований общих и специальных способностей, осуществленных в отечественной научной психологии. Анализируются трудности, связанные с определением понятий «способности» и «одаренность». Обозначено понимание природы творческих способностей и креативности. Рассматриваются психологическая сущность и специфика литературной деятельности как научного феномена. Дана характеристика литературно-художественным способностям как внутреннему психологическому регулятору личности. Показано, что способности в области литературного творчества напрямую соотносятся с художественным типом одаренности, обладающим как одинаковыми, имманентными иным видам одаренности качествами, так и своеобразными характеристиками, рознящими их с другими проявлениями способностей.
The article presents a theoretical and historical overview of the studies of general and special abilities carried out in the domestic scientific psychology. The difficulties associated with the definition of the concepts of “ability” and “giftedness” are analyzed. The understanding of the nature of creativity and creativity is indicated. The psychological essence and specificity of literary activity as a scientific phenomenon are considered. The characteristic of literary and artistic abilities as an internal psychological regulator of personality is given. It is shown that the ability to literary creativity refers to the artistic type of giftedness, which has both common qualities inherent in other types of giftedness, and peculiar, distinguishing it from other types of abilities. It is concluded that most of the complexities and contradictions in the study of the phenomenology of abilities are mainly associated with the comprehension of what ontologically represents this mental phenomenon. It is shown that the psychology of literary and artistic creativity and related areas of scientific knowledge are very complex and multifaceted. It is said that the creation of conditions that ensure the identification and creative development of literary gifted persons, the realization of their potential is among the priorities of modern society. Of great importance for the development of literary abilities is the social, including educational environment.
Changes in Weight, Body Image Perception and Self-Efficacy: A Study on Italian Adolescents during the Pandemic Period
Authors: Lorenzo Aurelia De , Lattke Lynda Stella , Rabaglietti Emanuela 
Published: December 2021

The lockdown period in Italy, due to Covid-19 government restrictions, caused sedentary behavior and a reduction in physical activity, with an increase in body weight and a change in body perception. Body image includes beliefs about one’s appearance. Women tend to exhibit poor body image compared to men; if we consider adolescence, this difference tends to be greater. In addition, only a small percentage of adolescents believe their body image to be adequate. Given that adolescence represents one of the periods with the highest level of physical change, including changes in weight, height, and body shape, we wanted to study how self-efficacy can be affected by body image. Studies have shown that self-efficacious students tend to be more persistent in the face of unexpected difficulties, particularly important in the current pandemic conditions. In our study, we analyze the relationship between the variation of perceived weight after two months of lockdown, and Self-efficacy, mediated by body image perception in a sample of Italian adolescents. Simple mediation analyses were conducted using PROCESS 3.5 for SPSS 27. Two-hundred and fifty high school students from northern Italy took part in the study (82% female, with a mean age of 16 years ±1,43). The data confirmed a partial mediation effect of body image perception. These results highlight how body image assumes significance for one of the most relevant developmental tasks for adolescents related to evaluation and self-perception affecting their self-efficacy, which is also a predictor of their academic achievement. We hope that studies like these can support the importance of interventions aimed at promoting well-being among adolescents, specifically regarding aspects of physical and motivational self-evaluation.
Map of educational resources used by medical students. Competitiveness of resources of HE institution (comparison of the 2020 and 2021 results)
Authors: Shamardina L. A. , Meshechak N. A. 
Published: December 2021

Introduction. Educational resources for medical students are not limited to traditional resources available in the university electronic environment of (subscribed or created at the university). Studies of the usage statistics of the university information-educational environment cannot give a reliable answer to the question of what resources students use. The study analyzes the survey data on the use of publicly available and commercial educational services along with the university resources. In result, we determine how the structure of the information and educational environment of the university meets the identified needs of students.Methods. In April 2021, we conducted an online survey of 1,765 students from 10 medical universities. Respondents were proposed to indicate the frequency with which they use different educational resources. We compare the 2021 results with the data of the 2020 survey using the methods of statistical analysis. Comparison of the use of the same type of university resources, publicly available and purchased are performed. The risks of the use of information resources of the university are assessed. Relationships between the use of different resources have been determined. Clusters of respondents demonstrating similar informational behavior are identified.Results. No significant changes in the frequency of use of information resources have been registered since 2020. Students prefer to use free resources regardless of their source. Frequent viewing of teachers’ online lectures reduces interest in face-to-face lectures, and frequent use of paid video resources or mobile applications reduces interest in the university resources as a whole. Close links have been found between the use of different commercial resources. 42.3 % of students prefer the university-created resources, whereas 38.6 % of students are focused at the publicly available resources and 19.1 % prefer technological resources from any source.Conclusion. The information resources of the university compete for the attention of students with a huge number of third-party resources. High-quality video content can significantly increase the use of university resources. An expert assessment of popular medical resources and an increase in students’ awareness of the quality of these resources is needed.
Conjunctival herpetic ulcer in an immunosuppressed patient with birdshot chorioretinopathy
Authors: Fernández-Hortelano Ana , Guzman-Almagro Elena , Castro-Rebollo María , Izquierdo-Rodríguez Carlos , González Martin-Moro Julio 
Published: December 2021

Introduction: Herpes Simplex Virus (HSV) is a human herpesvirus responsible for systemic infections. Ocular involvement spans all ocular tissues. Corneal lesions, such as dendritic or geographic ulcers, are frequently found in HSV keratitis while conjunctival lesions have been described as infrequent.
Clinical case: A 62-year-old man diagnosed with Birdshot chorioretinopathy presented a stye in his eyelid that was treated with oxytetracycline-hydrocortisone ointment. One week later he returned presenting several small dendritic corneal ulcers in both eyes and a conjunctival ulcer in one of them. All lesions healed completely after treatment with topical acyclovir ophthalmic ointment at 3%.
Conclusions: We should pay attention to the conjunctiva and not merely focus on the cornea when examining patients with herpetic eye disease, especially if being treated with inmunosupressors.