bluuebunny/crossref_metadata_2025_split huggingface dataset:
OPTIMALISASI KINERJA PERUSAHAAN MELALUI MODEL KOMITMEN PROFESI DAN KEPUASAN KERJA DI ERA INDUSTRI 4.0 DI PT. SARASWANTI ANUGERAH MAKMUR CABANG MEDAN
Authors: Pasaribu Donal Frensius , Affandi Azhar 
Published: December 2021

Bergulirnya era industri 4.0 maka perusahaan diharapkan dapat menerapkan konsep-konsep yang dapat mendukung terciptanya organisasi yang efektif dan efisien. Kinerja perusahaan yang baik merupakan muara akhir yang ingin dicapai oleh semua organisasi. Untuk mencapainya dibutuhkan dukungan semua bagian dalam organisasi, termasuk karyawan. Banyak teori yang menyatakan bahwa komitmen profesi dan kepuasan kerja berpengaruh positif kepada performa perusahaan. Riset ini dilakukan di PT. Saraswanti Anugerah Makmur cabang Medan dengan 60 orang subjek penelitian. Tujuan utama penelitian ini adalah melihat model komitmen profesi dan kepuasan kerja karyawan diasumsikan dapat memberikan sumbangan kepada kinerja perusahaan. Hasilnya menemukan bahwa komitmen terhadap profesi dan kepuasan kerja mempengaruhi kinerja perusahaan berarti bahwa apabila model komitmen profesi dan kepuasan kerja mengalami peningkatan maka diharapkan performa perusahaan juga mengalami peningkatan.
Kata kunci: kinerja perusahaan, kepuasan kerja, komitmen profesi
DAMPAK PANDEMI COVID-19 TERHADAP KESEJAHTERAAN PETANI TEMBAKAU DI KABUPATEN JOMBANG
Authors: Wahyuni Dwi , Dinaloni Diah 
Published: December 2021

Tembakau merupakan salah satu komoditas tanaman penting di Indonesia. Peran tembakau bagi masyarakat cukup besar karena aktifitas produksi dan pemasarannya melibatkan sejumlah penduduk untuk mendapatkan penghasilan dan pekerjaan. Jadi petani tembakau merupakan sumber daya manusia yang menjadi tulang punggung pembangunan ekonomi, khususnya disektor pertanian. Fenomena yang didapat oleh peneliti saat melakukan observasi diketahui bahwa pada masa pandemi covid-19 harga tembakau mengalami penurunan dan tentu saja hal tersebut berdampak langsung pada kesejahteraan petani tembakau di Kabupaten Jombang.Penelitian ini bertujuan untuk menganalisis dan mendeskripsikan dampak pandemi covid-19 terhadap kesejahteraan petani tembakau di Kabupaten Jombang. Penelitian ini merupakan penelitian kualitatif fenomenologis. Adapun yang menjadi informan dari penelitian ini yaitu petani tembakau baik pemilik lahan maupun buruh tani. Teknik pengumpulan data dilakukan melalui observasi, wawancara terbuka dan penelusuran data online. Untuk menganalisis data dari hasil wawancara, peneliti menggunakan teknik analisis yang terdiri atas reduksi data, paparan data, penarikan simpulan dan verifikasi.Hasil penelitian menunjukkan bahwa menurunnya harga temabakau pada masa pandemi covid-19 disebabkan oleh beberapa hal yaitu (1) faktor cuaca seperti intensitas curah hujan yang tinggi membuat daun tembakau menjadi rusak dan busuk sehingga kualitasnya menjadi jelek, hal ini tentu saja mempengaruhi harga jualnya menjadi turun; (2) kebijakan PPKM yang diberlakukan oleh pemerintah pada masa pandemi covid-19 menyebabkan pabrik rokok mengurangi aktifitas produksinya, sehingga permintaan tembakau menurun dan berpengaruh terhadap harga tembakau yang mengalami penurunan juga. Harga tembakau yang turun tersebut berpengaruh pada pendapatan yang diperoleh petani tembakau pada saat panen, sehingga pendapatan yang menurun tentu saja berdampak pada kesejahteraan petani tersebut. Pendapatan dari penjualan tembakau hanya cukup untuk menutup biaya produksi (pembelian bibit, pupuk, upah buruh tani) saja yang dikeluarkan oleh petani selama masa tanam tembakau, sedangkan untuk menutupi kebutuhan lain para petani tembakau ini harus melakukan pekerjaan sampingan seperti berdagang dan ternak kambing. Kata kunci: pandemi covid-19, kesejahteraan, petani tembakau
PENGARUH GAYA KEPEMIMPINAN DAN MOTIVASI TERHADAP KINERJA DENGAN MODAL PSIKOLOGIS SEBAGAI MODERATING
Authors: Aldiansyah Muhammad , Lukito Hendra 
Published: December 2021

Suatu organisasi harus memiliki nilai lebih dalam hal sumber daya manusia agar dapat bersaing dengan organisasi lainnya. Organisasi dalam melaksanakan program kerja yang telah disusun pada dasarnya selalu bertujuan untuk mencapai tujuan organisasi. Salah satu caranya adalah dengan meningkatkan kinerja pegawai. Kinerja adalah hasil atau tingkat keberhasilan seseorang secara keseluruhan selama periode tertentu didalam melaksanakan tugas. Penelitian ini dilakukan bertujuan untuk mengetahui pengaruh gaya kepemimpinan dan motivasi terhadap kinerja dengan modal psikologis sebagai moderating pada pegawai Fakultas Ilmu Keolahragaan Universitas Negeri Padang. Variabel independen pada penelitian ini diantaranya gaya kepemimpinan dan motivasi, sedangkan kinerja pegawai dijadikan sebagai variabel dependen, dan modal psikologis sebagai variabel moderasi. Teknik pengambilan sampel dilakukan dengan sampling jenuh dimana menjadikan seluruh populasi sebagai sampel yang didapat sebanyak 66 pegawai yang ada pada Fakultas Ilmu Keolahragaan Universitas Negeri Padang. Dengan menggunakan instrumen berupa kuesioner yang dianalisa memakai analisis PLS-SEM, dimana hasil yang diperoleh yaitu gaya kepemimpinan dan motivasi berpengaruh signifikan dan positif terhadap kinerja pegawai. Modal psikologis dapat memoderasi gaya kepemimpinan dan motivasi terhadap kinerja pegawai. Disarankan kepada pimpinan Fakultas Ilmu Keolahragaan Universitas Negeri Padang perlu memberikan pelatihan pengembangan, update ilmu para pegawai, karena dalam pengisian kuesioner responden masih rendah nilai terampil dibandingkan standar prosedur yang ada dalam bekerja.Kata Kunci : Gaya kepemimpinan, motivasi, modal psikologis, kinerja pegawai
Monitoring of the epizootic situation sheep strongyloidiasis on Ukrainian territory
Authors: Sorokova S. 
Published: December 2021

One of the reasons that reduce the efficiency of sheep breeding development and lead to significant economic losses of the industry in Ukraine and the world is helminthic diseases, particularly strongyloidiasis caused by parasitic nematodes. Strongyloides parasitize in the small intestine of animals and lead to slow growth and development of young sheep, diarrhea, anemia, ataxia. At the high intensity of invasion - animals can die. The study aimed to analyze monitoring studies on the prevalence of strongyloidiasis in sheep in Ukraine based on statistical data of the reporting documentation of the State Research Institute for Laboratory Diagnostics and Veterinary Sanitary Examination during 2016–2020. Studies have shown that helminthiasis of sheep is a common invasion in farms of various forms of ownership in Ukraine, where the extent of the invasion ranged from 1.44 to 3.27 %. The share of helminthiasis of the digestive tract of sheep from the total number of detected helminthiasis reaches 84.21 %. The most common of the helminthiases of the gastrointestinal tract were nematodes; their share was 63.07 %. Trematodes and cestodes were diagnosed less frequently; their share among helminthiases of the digestive tract was 35.05 and 1.88 %, respectively. It was found that among the nematodes of the digestive tract parasitizing in sheep in Ukraine, the largest share was strongylidosis, in particular bunostomosis, nematodyrosis, hemonchosis (65.20 %), and strongyloidiasis (33.92 %). A smaller proportion were esophagostomosis (0.74 %) and trichurosis (0.14 %). Indicators of prevalence were: for strongylidosis (bunostomosis, nematodyrosis, hemonchosis) – 10.98 %, for strogiloidiasis – 4.48 %, for esophagostomosis – 0.42 %, for trichurosis – 0.21 %. In terms of years, the rates of damage to sheep by the causative agent of strongyloidiasis fluctuated significantly with the increasing prevalence of strongyloidiasis invasion during 2019–2020. Indicators of infestation of sheep with the causative agent of strongyloidiasis during the study period in Ukraine were at the level of 1.91 % (2018) to 16.14 % (2019). The data we obtained testify to the urgency of the problem of nematodes, particularly strongyloidiasis of sheep in Ukrainian farms, and lead to more thorough research on epizootological, biological features of the causative agent strongyloidiasis and the introduction of effective treatment and prevention measures.
Валідація теплогідравлічної моделі реакторної установки з детальною розбивкою опускної ділянки для аналізу термічних навантажень на корпус реактора
Authors: Mazurok A. , Alekseev J. , Krushynskyy A. , Kornytskyi A. 
Published: December 2021

Виконано динамічну валідацію теплогідравлічної моделі реакторної установки енергоблока № 1 Южно-Української АЕС для коду RELAP5/mod3.2 із застосуванням детальної розбивки опускної ділянки реактора. Підтверджено здатність моделі адекватно відображати поведінку основних параметрів, роботу систем і обладнання реального енергоблока, а отже, її придатність для аналізу термічних навантажень на корпус реактора.
Оцінка впливу додаткової системи аварійної живильної води на показник частоти пошкодження активної зони реакторів ВВЕР‑440/213 на прикладі енергоблоків №№ 1, 2 Рівненської АЕС
Authors: Kovtonyuk P. , Sevbo O. , Nevmerzhytskiy V. , Okhrimchuk V. , Ochakovskaya O. 
Published: December 2021

За допомогою засобів імовірнісного аналізу безпеки оцінено вплив додаткової системи аварійної живильної води на показник частоти пошкодження активної зони реакторів енергоблоків №№ 1, 2 РАЕС. Порівнюються результати впливу попереднього та впровадженого технічного проекту системи на цей показник. Показано особливості моделювання елементів системи.
Аналіз нормативної документації на труби, елементи і деталі трубопроводів для атомно-енергетичного комплексу України
Authors: Vakhrusheva V. , Buryak T. , Yaroshenko N. 
Published: December 2021

Проаналізовано стандарти і технічні умови на труби та деталі трубопроводів для АЕС. Показано необхідність перегляду й шляхи актуалізації документів відповідно до сучасних вимог.
Рекомендації щодо інспекційних перевірок АЕС із дотримання експлуатуючою організацією принципу ALARA
Authors: Lytvynska T. , Nosovsky A. , Goshko A. 
Published: December 2021

Наведено рекомендації щодо переліку та змісту інспекційних процедур, за допомогою яких регулюючий орган може ви­значити шляхи та методи запровадження принципу оптимізації (принципу ALARA) в практичну діяльність АЕС, оцінити ефективність застосовуваних оптимізаційних процедур.
Аналіз важкої аварії у басейні витримки відпрацьованого палива для енергоблока ВВЕР-1000 за допомогою розрахункового коду MELCOR 1.8.5
Authors: Vorobyov Y. , Perepelitsa M. , Sverdlov V. 
Published: December 2021

Розроблено модель басейну витримки відпрацьованого палива енергоблока ВВЕР-1000 для комп’ютерного коду MELCOR 1.8.5. Проаналізовано вихідну подію втрати тепловідведення від басейну витримки (БВ), визначено часові рамки пошкодження палива, кількість згенерованого водню, оцінено радіаційні наслідки. На прикладі різних варіантів завантаження басейну витримки визначено закономірності важкої аварії, які дозволяють перенесення (масштабування) результатів на інші конфігурації БВ.
Автоматизовані системи контролю радіаційної обстановки
Authors: Barbashev S. , Prister B. 
Published: December 2021

Наведено стислий аналіз стану автоматизованого контролю радіаційної обстановки в довкіллі у районах розташування АЕС України та інших країн. Розглянуто питання побудови Єдиної державної автоматизованої системи контролю радіаційної обстановки на території України. Описано загальні принципи побудови систем, які розглядаються в статті, та методи їх реалізації.
VILLA SAVOYE: SÍNTESE DO PENSAMENTO CORBUSIANO
Authors: Feiden Alessandra Cristina , De Camargo Mello Cláudio Renato 
Published: December 2021

A Segunda Revolução Industrial proporcionou avanços tecnológicos em diversos campos do conhecimento, entre eles a arquitetura, onde o surgimento de novos materiais – a exemplo do concreto, do aço e do vidro – possibilitaram a criação de novas formas a partir das concepções dos principais arquitetos do período. Nesta direção, este artigo propõe algumas reflexões sobre o pensamento do arquiteto Le Corbusier (1887-1965), expressos em suas ideias e conceitos perpetuados como: “a casa é uma máquina de morar” e “promenade architecturale”. Utilizando como metodologia de investigação a pesquisa bibliográfica apoiada nas referências encontradas sobre a Villa Savoye, projetada por este arquiteto e construída em Poissy na França, entre 1929-31. Considerando-se que, a residência se tornou um dos principais símbolos da arquitetura moderna por representar a síntese das premissas corbusianas apresentadas nos “cinco pontos” da arquitetura moderna, concebidos em 1926, entendemos que, a partir de uma análise detalhada sobre a edificação – de sua história à sua concepção e execução, possamos estar contribuindo com futuros estudos que promovam desdobramentos ao tema.
Shelf-life extension of meat products by cellulose acetate antimicrobial film incorporated with oregano’s essential oil
Authors: Paganini Camila Casagrande , Laroque Denise Adamoli , Carciofi Bruno Augusto Mattar , Aragão Gláucia Maria Falcão de 
Published: December 2021

This study aimed to apply cellulose acetate (CA) films incorporated with oregano essential oil (OEO) to inhibit bacteria growth associated with spoilage of meat products (Weissella viridescens (microaerophilic) and Pseudomonas fluorescens (aerobic)) and evaluate its effect on the shelf life of vacuum-packed sliced ham (VPSH). CA films were produced using acetone solvent, adding 25, 35, 50, or 75 mg of OEO per film. Antimicrobial activity and mechanical properties of films were determined. CA films in Petri dishes showed a better antimicrobial effect against W. viridescens than P. fluorescens. As VPSH, presents a microaerophilic environment, product shelf life was determined fitting Baranyi and Roberts’ model to W. viridescens’ growth experimental data, at 8 °C. OEO did not modify films’ mechanical properties. Application of the CA film with 75 mg of OEO decreased value of W. viridescens, increased its value, resulting in a ham` shelf-life increased by eight days, demonstrating excellent application potential.
Clinical Significance of Serum Oxidative Stress Markers to Assess Disease Activity and Severity in Patients With Non-Segmental Vitiligo
Authors: Li Shuli , Dai Wei , Wang Sijia , Kang Pan , Ye Zhubiao , Han Peng , Zeng Kang , Li Chunying 
Published: December 2021

Non-segmental vitiligo (NSV) is a chronic autoimmune disease characterized by progressive depigmentation of the skin. Oxidative stress (OS) has been proposed as one among the main principal causes in the development and establishment of a sustained autoimmune state in patients with NSV. However, the disease-associated OS biomarkers in clinical practice are not well studied. In this study, we found significantly reduced antioxidant enzymes [catalase (CAT) and superoxide dismutase (SOD)], total antioxidant capacity (TAC), and increased levels of lipid oxidation product malondialdehyde (MDA) and oxidative DNA damage byproduct [8-hydroxy-2-deoxyguanosine (8-OHdG)] in serum of NSV patients compared with healthy controls (HC). Serum TAC, MDA, and 8-OHdG levels were correlated with disease activity in all patients with NSV and much lower in patients receiving conventional treatment in the past 1 year compared to that without treatment. In addition, both serum MDA and 8-OHdG levels were significantly correlated with CXCL10 expression in patients with NSV. And the serum TAC, MDA, and 8-OHdG levels were also correlated with affected body surface area and Vitiligo Area Scoring Index score in patients with NSV. This study demonstrates dysregulated OS status in patients with NSV and provides the evidence that the serum TAC, MDA, and 8-OHdG have a capacity to indicate the activity and severity in patients with NSV.
Humulane-Type Macrocyclic Sesquiterpenoids From the Endophytic Fungus Penicillium sp. of Carica papaya
Authors: Wang Fu-Run , Yang Li , Kong Fan-Dong , Ma Qing-Yun , Xie Qing-Yi , Wu You-Gen , Dai Hao-Fu , Chen Ping , Xiao Na , Zhao You-Xing 
Published: December 2021

Three new humulane-type sesquiterpenoids, penirolide A (1), penirolide B (2), and 10-acetyl-phomanoxide (3), together with three known compounds aurasperone A (4), pughiinin A (5), and cyclo(l-Leu-l-Phe) (6) were isolated from the endophytic fungus Penicillium sp. derived from the leaves of Carica papaya L. Their structures including their absolute configurations were determined based on the analysis of NMR and HRESIMS spectra, NMR chemical shifts, and ECD calculations. Compounds 2, 3, 5, and 6 significantly inhibited glucagon-induced hepatic glucose production, with EC50 values of 33.3, 36.1, 18.8, and 32.1 μM, respectively. Further study revealed that compounds 2, 3, 5, and 6 inhibited hepatic glucose production by suppression of glucagon-induced cAMP accumulation.
Community-Based Monitoring Detects Sources and Risks of Mining-Related Water Pollution in Zimbabwe
Authors: Ruppen Désirée , Chituri Owen A. , Meck Maideyi L. , Pfenninger Numa , Wehrli Bernhard 
Published: December 2021

Although mining and mineral processing are vital for many economies in the Global South, they are associated with enormous challenges of managing potentially devastating environmental impacts. In contexts where environmental oversight agencies often lack financial and personal capacities to fulfill their role, community-based monitoring might be a valid alternative to monitor potential environmental impacts. In this study, we present the setup and the implementation of a citizen science project to monitor water quality parameters in a river downstream of a coal mining area in Hwange, Western Zimbabwe. In a joint effort over 1.5 years, community monitors and scientists took close to 800 water samples in the Deka River and effluent channels. The data allowed identifying sources of pollution and relating these to past and present mining activities. The primary source of acid mine drainage came from abandoned underground mine sites. Illegal mine water dumping from active mine sites accentuated the problem and resulted in fish kills and food risks for the local population. Concentrations of manganese, nickel and arsenic were exceeding national fresh water guidelines and international drinking water standards. Manganese concentrations exceeded guidelines by a factor of 70 resulting in a public health risk. In this study, we showed that community-based monitoring offers a promising approach to establish a high-quality dataset for assessing mining-related risks if the implementation of sampling protocols is followed tightly. The monitoring scheme significantly improves the collection and interpretation of water quality data in challenging contexts where governmental institutions and industrial players are not enforcing environmental standards.
Reductive Effect of Acitretin on Blood Glucose Levels in Chinese Patients With Psoriasis
Authors: Qian Hua , Kuang Yehong , Su Juan , Chen Menglin , Chen Xiang , Lv Chengzhi , Chen Wangqing , Zhu Wu 
Published: December 2021

Background: Psoriasis is a skin condition associated with increased risks of developing metabolic diseases, such as diabetes and hyperlipidaemia. Retinoid drugs, including acitretin, are commonly used to treat psoriasis due to its low cost and tolerable side effects.Objective: This study aimed to explore the influence of acitretin on patients' metabolism levels, especially lipid and glucose.Methods: In this retrospective study, a total of 685 psoriatic patients and 395 age/sex matched controls were enrolled. The demographic and biochemical indexes of each participant were recorded. Acitretin (30 mg/d) combined with the topical ointment calcipotriol was used to treat the psoriatic patients, and the glucose and lipid profiles of patients before and after acitretin treatment were analyzed.Results: The blood glucose levels of 685 psoriasis patients were significantly higher than that of the control group (P &lt; 0.001), while the blood lipid levels showed no difference between psoriatic patients and the matched controls. Triglyceride and low-density lipoprotein levels were significantly increased in 247 patients (P &lt; 0.05) after 8 weeks of treatment with acitretin. Interestingly, there was a remarkable downward trend in body mass index (BMI) and blood glucose levels (P &lt; 0.05) after acitretin treatment. Additionally, expression of both GLUT1 and GLUT4 in HaCaT and HepG2 cells were significantly increased when treated with acitretin. Compared to acitretin-free cells, the uptake of 2-NBDG was significantly higher in HaCaT and HepG2 cells after incubation with 5000 ng/mL acitretin for 36 h.Conclusion: Acitretin plays a significant role of reducing the blood glucose level in psoriasis patients. The mechanism of lowering blood glucose may be through increasing glucose intake by cells, thereby reducing glucose levels in the peripheral blood.
Reference Standards for Newborn Screening of Metabolic Disorders by Tandem Mass Spectrometry: A Nationwide Study on Millions of Chinese Neonatal Populations
Authors: He Falin , Yang Rulai , Huang Xinwen , Tian Yaping , Pei Xiaofang , Bohn Mary Kathryn , Zou Lin , Wang Yan , Li Haibo , Wang Ting , Gu Maosheng , Jiang Tao , Chen Xigui , Zou Hui , Wei Hongwei , Tian Weibing , Tang Tian , Adeli Khosrow , Wang Zhiguo 
Published: December 2021

Introduction: The major clinical problem presently confronting the Chinese newborn screening (NBS) programs by tandem mass spectrometry (MS/MS) is the lack of comprehensive reference intervals (RIs) for disease biomarkers. To close this gap, the Chinese National Center for Clinical Laboratories (NCCL) launched a nationwide study to investigate the dynamic pattern of 35 MS/MS NBS biomarkers and establish accurate and robust RIs.Methods: Blood spot samples from 4,714,089 Chinese neonates were tested in participating centers/laboratories and used for study analysis. MS/MS NBS biomarker trends were visually assessed by their concentrations over age. Specific partitions were determined arbitrarily by each day and sex or by the statistical method of Harris and Boyd. RIs, corresponding to the 2.5th and 97.5th percentiles, as well as the 1th, 25th, 75th and 99th percentiles were calculated for each reference partition using a non-parametric rank approach.Results: Most MS/MS NBS biomarkers fluctuated during the first week of life, followed by a relatively stable concentration. Age and sex-specific RIs were established and presented an improved specificity over the RIs used in participating centers/laboratories. Females demonstrated higher 2.5th and 97.5th percentiles in all amino acids except arginine and ornithine than males, whereas males showed higher 2.5th and 97.5th percentiles in most acylcarnitines.Conclusion: The present study determined the dynamic trends of 35 MS/MS biomarkers and established age and sex-specific RIs, valuably contributing to the current literature and timely evaluation of neonatal health and disease.