bluuebunny/crossref_metadata_2025_split huggingface dataset:
Site preferences and ion dynamics in lithium chalcohalide solid solutions with argyrodite structure: I. A multinuclear solid state NMR study of the system Li6PS5-xSexI and of Li6AsS5I
Authors: Koch Barbara , Kong Shaio Tong , Gün Özgül , Deiseroth Hans-Jörg , Eckert Hellmut 
Published: October 2021

Abstract
A comprehensive multinuclear (7Li, 31P, 75As, 77Se, 127I) NMR study has been conducted to characterize local structural configurations and atomic distributions in the crystallographically ordered solid solutions of composition Li6PS5-x
Se
x
I (0 ≤ x ≤ 1) and in Li6AsS5I. Throughout the composition range, structural ordering between the atoms on the Wyckoff sites 4a and 4c is maintained, with the I− ions exclusively occupying the 4a sites. 31P magic-angle spinning nuclear magnetic resonance (MAS NMR) can serve to differentiate between the various possible PS4-n
Se
n

3− tetrahedral units in a quantitative fashion, indicating a preference of P-S relative to P-Se bonding. Each individual PS4-n
Se
n

3− tetrahedron is represented by a peak cluster containing up to five resonances, representing the five different configurations in which the PCh4
3− units are surrounded by the four closest chalcogenide anions occupying the 4c sites; the distribution of S2− and Se2− over these sites is close to statistical. Non-linear 7Li chemical shift trends as a function of x are interpreted to indicate that the Coulombic traps created by sulfur-rich PS4-n
Se
n

3− ions (n ≥ 2) within the energy landscape of the lithium ions are deeper than those of the other anionic species present (i.e. selenium-richer PCh4
3− tetrahedra, isolated chalcogenide or iodide ions), causing the Li+ ions to spend on average more time near them. Temperature dependent static 7Li NMR linewidths measured on Li6PS5I and Li6AsS5I indicate a two-step motional narrowing process characterized by a clear dynamic distinction between a more rapid localized intra-cage process and a slower, long-range inter-cage process. In the solid solutions this differentiation gradually disappears, leading to an overall increase of lithium ionic mobility with increasing selenium content, which can be attributed to the influences of higher anionic polarizability and a widening of the lithium migration pathways caused by lattice expansion. Furthermore, the low-temperature phase transition in Li6PS5I, which tends to immobilize the lithium ions below 170 K, is suppressed in the solid solutions. The results offer interesting new insights into the -structure/ionic mobility correlations in this new class of compounds.
ФЕНОМЕН ІНТЕРПРЕТАЦІЇ В КОНТЕКСТІ ГЕРМЕНЕВТИЧНОГО АНАЛІЗУ
Authors: Khalimon Roman Oleksandrovych 
Published: October 2021

У статті розглянуто феномен «інтерпретації» в контексті герменевтичного аналізу. Проаналізовано погляди дослідників герменевтики: Й. Хладного, Ф. Маєра, Й. Ернесті, Ф.Шлейєрмахера, Й.Дройзена, В.Дільтея, П.Рікера, А.Вайтгеда, М. Гайдеґґера, Г.‑Ґ.Ґадамера, В.Швирьова, С.Квіта та ін. на природу й сутність інтерпретації, її методи, структуру й значення в життєдіяльності людини.
Morphofunctional characteristics of single combats athletes as factors of success
Authors: Podrigalo Leonid V. , Podrihalo Olha O. , Jagiello Wladyslaw , Podavalenko Olexandr V. , Masliak Irina P. , Tropin Yuri M. , Mameshina Margarita A. , Galimskyi Volodymyr О. , Galimska Inna І. 
Published: October 2021

Background and Study Aim. The aim of the article is a comparative analysis of the morphofunctional characteristics of athletes of various types of martial arts as factors of success.
Material and Methods. The study participated students involved in martial arts (n = 29; age - 17.53 ± 0.15 years). The first group (group 1 - wrestlers) included judo, sambo, wrestling athletes (n = 12, age - 18.58 ± 0.38 years). The second group (group 2 - athletes of percussion martial arts) included athletes of karate, taekwondo (GTF), taekwondo (WTF), (n = 17; age - 18.12 ± 0.26 years). Determined 46 morphofunctional indicators: length and body weight; chest circumference in a pause, on inhalation and exhalation; length and circumference of the segments of the upper and lower extremities; wrist dynamometry. A goniometric study of the range of motion in the joints of the upper extremities was carried out. The dynamic grip strength was determined by the maximum frequency of hand squeezing in 10 seconds. To characterize the data, the median was determined - the first (25%) and third (75%) quartiles. Differences between groups were assessed using nonparametric criteria of Wilkinson-Mann-Whitney (U) and Rosenbaum (Q).
Results. Athletes in group 1 had a greater interquartile range compared to athletes in group 1 in the following indicators: body weight; chest circumference in a pause, on inhalation and exhalation; hand dynamometry of the right and left hands; maximum frequency of the hand grip in the impulse mode with the left hand; shoulder width; circumference of the shoulder, forearm, thigh and lower leg. Athletes of percussion martial arts were characterized by large values of the shin length. The amplitude of abduction and adduction in the right wrist joint, the amplitude of abduction in the left wrist joint was greater in the wrestlers. Athletes of percussion martial arts had a large amount of extension of the left wrist joint, flexion of the right elbow joint, extension and abduction of the right shoulder joint.
Conclusions. Analysis of morphofunctional indicators of athletes of various types of martial arts confirmed the specific effect of the sport on the body of athletes. The features that are the factors of success are highlighted. For wrestlers, these include hand strength in various modes. It allows to implement quickly and efficiently grip. This is the basis for a successful wrestling technique. Sufficient development of the muscles of the limbs ensures the execution of throws in wrestling. The lengthened calf size contributes to a more effective kick in martial arts. Goniometric features of movements reflect the possibility of high-quality gripping, striking or blocking. The used morphofunctional indicators can be applied to predict the success of athletes in various types of martial arts.
A biomechanical examination of the inclusion of active flexibility in artistic gymnastic movements requiring mobility
Authors: Berisha Milaim 
Published: October 2021

Background and Study Aim. The purpose of the study is a biomechanical examination of the inclusion of active flexibility in artistic gymnastic movements requiring mobility (muscles' ability to stretch), flexibility and other motor abilities such as force, power, etc.
Material and Methods. The study included 17 girl gymnasts aged 7-9 years old, with a body height of 140.7±10.2, weight of 34.1±6.4, and a body mass index of 17.6±3.0. Data collection in the study was made by using performance tests developed by FIG such as a Forward-Backward Split, Side Spit, Arm-Trunk Angle Backward, Trunk Bent Forward, Leg Raise forward, Leg Raise Sideward, Bridge, Standing long Jump, Lift Trunk Forward-60secs, Angle Degree of the Leg Split Position in Cartwheel, and Arm-Upper Body Angle Backward in Bridge Technique. The Kinovea 0.8.15 program was used in the data analysis of the variables in the study. The SPSS 24 software program was used for the data analysis. Percentages of the angle degree calculated by the formula “%= (angle0 of the mobility in functional movement / angle0 of the active flexibility) *100” were found.
Results. Results indicate that active flexibility was 90% functional in the leg raise sideward, 90% in the leg split during execution of the cartwheel, 17.5% in the bridge technique, and completely functional for the flexibility ratio expressed in the leg raise forward technique. In the analysis of the various elements of the similar biomechanics, the anatomic structure and similar body planes, it was concluded that active flexibility expressed in the movements required a mobility of around 65-75%.
Conclusions.. it was determined that the functionality rate of the techniques requiring active flexibility and requiring mobility of the same biomechanical and anatomical structure was around 65-75%. Therefore, to execute 100% of the flexibility in action (during active elements) as it is in a passively or actively, it may significantly increase force, motor control, dynamic balance, coordination etc., in the large range of motion.
Effects of low intensity interval training on physiological variables of university students
Authors: Ketema Assegid K. 
Published: October 2021

Background and Study Aim. This study was to investigate the effects of low-intensity interval training on the physiological variables of university students.
Material and Methods. Forty male sports science students aged 18-25 years were randomly assigned to the Experimental group (n=20) and the Control group (n=20). The Experimental group underwent low-intensity interval training for eight weeks, whereas the Control group did not. Measurements of physiological variables such as resting heart rate, respiratory rate, recovery heart rate, breath-hold time, maximal oxygen uptake, and blood pressure were obtained for all subjects before and after the intervention. To compare the mean physiological variables between the experimental and control groups, an independent samples t-test was used.
Results. Statistical significance was set at p 0.05. After the training intervention, the experimental group showed significantly better improvements than the control group in resting heart rate, respiratory rate, recovery heart rate, breath-holding time, maximal oxygen uptake, and blood pressure (p 0.05). Post intervention maximum oxygen uptake was statistically significant with t (38) = 3.086, p value 0.004. Post experiment systolic blood pressure was statistically significant with t (38) = -2.405, p value 0.021 for low intensity interval training and control group. Post experiment diastolic blood pressure was statistically highly significant with t (38) = 0.569, p value 0.001 for low intensity interval training and control group. The result of the study showed that there was a significant difference in post rest heart rate, respiratory rate, recovery heart rate, systolic blood pressure, diastolic blood pressure, breath holding and maximal oxygen uptake between the low intensity interval training and the control group (p 0.05).
Conclusions. Thus, it was concluded that eight weeks of low-intensity interval training show significant improvement in physiological variables of university students.
Molecular genetic predictors of metastatic lesions of regional lymph nodes in patients with breast cancer
Authors: Rodionov V. V. , Burmenskaya O. V. , Kometova V. V. , Trofimov D. Yu. , Rodionova M. V. , Ashrafyan L. A. 
Published: October 2021

Objective: to identify molecular genetic predictors of metastatic spread to regional lymph nodes in patients with breast cancer (BC) based on the analysis of gene expression profile of the primary tumor.Materials and methods. The study included 358 patients with BC who underwent surgical treatment in breast cancer department of Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. Among all included into the study patients, 132 (36.9 %) had metastases in at least one axillary lymph node. Molecular genetic examination of the tumor tissue was carried out using reverse transcription polymerase chain reaction; the diagnostic panel consisted of 45 functional and 3 reference genes. Results. Patients with metastases to regional lymph nodes were generally younger (p = 0.006), had larger primary tumor (p<0.001) and higher total malignancy score (p<0.001). The groups were also significantly different in tumor location (p = 0.005). Comparative analysis of transcriptome tumor profiling revealed statistically significant differences between groups in the level of expression of three genes: TMEM45A (p = 0.016), CCND1 (p = 0.019), and MIA (p = 0.046). Based on the data obtained we used mathematical modeling and created a predictive model, which with a high degree of probability (AUC = 0.791) allowed to predict the presence of regional lymph nodes metastases in patients with BC.Conclusion. TMEM45A, CCND1 and MIA gene expression in the primary tumor were the markers of lymph node involvement in BC. The developed predictive genetic signature can become an additional diagnostic tool to predict the risk of lymph node metastases at the point of planning the volume of axillary surgery in patients with BC.
Comparative assessment of the diagnostic efficiency of medical imaging methods, as exemplified by magnetic resonance imaging and contrast-enhanced ultrasound examination, based on propensity score matching
Authors: Busko E. A. , Goncharova A. B. , Buchina D. A. , Natopkina A. S. 
Published: October 2021

Objective: сomparative assessment of the diagnostic efficiency of magnetic resonance imaging (MRI) and contrastenhanced ultrasound examination in the primary diagnosis of breast cancer based on propensity score matching.Materials and methods. From 2017 to 2018 on the basis of the National Medical Research Center of Oncology named after N.N. Petrov 176 women with various complaints of breast diseases were examined using MRI, which was carried out on a Magnetom Aera (Siemens) and Signa Excite HD (GE) apparatus with a magnetic field strength of 1.5 T and special surface breast coil. From 2018 to 2019 on the basis of the National Medical Research Center of Oncology named after N.N. Petrov 277 women with various complaints of breast diseases were examined using multiparametric ultrasonography (US) consisting of gray-scale US, color Doppler US, strain US, and contrast enhanced US, performed on a Hitachi Hi Vision Ascendus ultrasound scanner using a linear transducer in the frequency range 5–13 MHz. To verify the lesions, the patients underwent histological or cytological examination. The results of ultrasound examination, histological and cytological conclusions were entered into the database containing 453 diagnostic records: 277 were obtained using the multiparametric US and 176 – using the MRI method. To solve the problem, the propensity score matching algorithm was used: building a model, calculating conditional probabilities, balancing, checking the balance quality, evaluating efficiency. The main and auxiliary characteristics of the methods of MRI and contrast-enhanced ultrasound before and after the selection of pairs are given in the work.Conclusion. The proposed algorithm is implemented in the R language. The results of the program are that both diagnostic methods showed excellent results, 95 % confidence intervals almost completely overlap, from which a preliminary conclusion should be made that these methods are equivalent in efficiency in the primary diagnosis of breast cancer.
Phyllodes breast tumor. From diagnostic to pathomorphological examination
Authors: Solodkiy V. A. , Khodorovich O. S. , Kalinina-Masri A. A. , Sarkisyan K. D. , Sherstneva T. V. , Kleshneva V. O. , Kanakhina L. B. , Lazukina I. A. , Letts-Orletsov K. K. 
Published: October 2021

Background. Phylloid tumors are a fairly rare pathology (about 0.3–0.5 % of all breast tumors), which is why there is no single protocol for the treatment of this pathology. Also, due to the lack of data and the rare occurrence, it is difficult to diagnose and choose the final management tactics of the patient. Phylloid tumors can be benign, borderline, and malignant neoplasms, which also complicates the treatment process. The final decision on the choice of patient management tactics can be made only after receiving the results of a planned pathomorphological examination.Materials and methods. In this article, we will discuss the results of major retrospective studies, including data on epidemiology, etiology, diagnostic approach, strategies and results of treatment of phylloid breast tumors, as well as present data on patients treated at the Russian Scientific Center of Radiology of the Ministry of Health of the Russian Federation for the period from January 2010 to February 2021.Results. The main methods of instrumental diagnosis of phylloid tumors are mammography, ultrasound and MRI. Morphological examination is important in making a diagnosis. Fine-needle biopsy often does not allow establishing an accurate diagnosis, and therefore the main method of diagnosis remains pathohistological examination. The main method of treatment of phylloid tumors remains surgical, where, depending on the trepan biopsy, the question of the feasibility of performing an organ-preserving operation is decided.Conclusion. Phylloid tumors are a rare type of breast neoplasm, which is the reason for the relatively small amount of scientific research that addresses this particular problem.
Estimating long-term overall survival with olaparib as maintenance therapy in patients with newly diagnosed advanced ovarian cancer with BRCA mutations
Authors: Avxentyev N. A. , Khokhlova S. V. , Frolov M. Yu. , Makarov A. S. 
Published: October 2021

Background. According to randomized clinical trial SOLO1 olaparib statistically significantly improves progression-free survival versus placebo as a maintenance monotherapy in patients aged 18 and over with newly diagnosed advanced ovarian cancer with BRCA mutations, who had response to first-line chemotherapy. As the data on overall survival (OS) in this trial remains interim it is still uncertain whether treatment with olaparib can provide any benefits in terms of OS.Objective: to evaluate a long-term OS for olaparib versus placebo as a maintenance monotherapy in patients with newly diagnosed advanced ovarian cancer with BRCA mutations, who had response to first-line chemotherapy.Materials and methods. A 10-year mathematic model of disease progression and survival on olaparib versus placebo was developed. Modelling was based on data on progression-free survival from SOLO1 trial and data on OS after platinum-sensitive and platinum-resistant relapses from OCEANS and AURELIA trials. Additionally, patients who haven’t been treated with olaparib after first-line therapy in base-case scenario were assumed to get olaparib as a second-line treatment after platinum-sensitive relapse; mortality modelling for these patients was based on data from SOLO2 trial.Results. Median OS for olaparib was 107 months versus 66 months for placebo. 46 % of patients treated with olaparib were alive by the end of 10-year modelling period, but only 28 % patients from the placebo group. Hazard ratio of death for olaparib versus placebo was 0.64 (95 % confidence interval 0.49–0.84). Probabilistic sensitivity analysis showed robustness of these results.Conclusion. Using olaparib as a maintenance therapy in patients with newly diagnosed advanced ovarian cancer with BRCA mutations, who had response on first line chemotherapy, statistically significantly reduces risk of death by 36 %, compared to placebo.
Prevalence of Intestinal Parasite Infections in Stray Dogs in Taif Region, KSA
Authors: Malki Jamila S. Al 
Published: October 2021

Background: The study of intestinal parasites that occur in stray dogs in the Taif region, KSA, is most important since there is little data available on this subject. Methods: Dog fecal samples were collected from 129 dogs in three different areas. Fecal samples were processed and analyzed by different mount techniques including, parasitological examination, wet-mount preparation and modified Kinyoun’s acid-fast technique. Result: The total prevalence of enteric parasites was 115 positive cases; for helminths was (62.7%) and for protozoa (26.3%). Mixed infection was higher than single infection in three areas. The total prevalence of helminths eggs by different mount preparation recovered from fecal sample examination from single or mixed form E. granulosus, T. canis and T. vulpis was of high infection rate (15.5%), (10.07%), (10.07%), followed by A. lumbercoides (7.7 %). Finally, T. leonine (6.9%), both A. caninum and A. braziliense are of the same percentage (6.2%). Concerning single and mixed protozoa infection, Giardia was of a high prevalence (16.2%), followed by Cryptosporidium (8.5%) and finally E. histolytica (1.5%) in fecal samples of doges. These data revealed that infection levels of parasites in stray dogs in the studied areas were high, knowing that this is the first study for mixed infections between dogs and humans in KSA.
Effect of Hydrogen Peroxide Pretreatment on Physiological and Biochemical Variables during Germination of Alfalfa Seeds
Authors: Muñoz-Salinas F. , Tovar-Pérez E.G. , Guevara-González R.G. , Loarca-Piña G.F. , Torres-Pacheco Irineo 
Published: October 2021

Background: Hydrogen peroxide is reactive oxygen species that plays role in plant response to biotic and abiotic stress. The pretreatment with hydrogen peroxide can confer an adaptive capacity for the plants in unpredictable environments. The alfalfa (Medicago sativa L.) is the legume more utilized in animal feeding in the world. Moreover, the alfalfa sprouts are known for the phytochemicals that promote health with antioxidant properties. Methods: This work aimed to determine the effect of hydrogen peroxide in the pretreatment process of alfalfa seeds on variables as total germination, speed of germination, activity and antioxidant enzymes. The alfalfa seeds were soaked for 12 h in the next treatments 0, 98, 294, 490, 784, 980 mM of hydrogen peroxide. Result: The results showed that total germination was higher with the hydrogen peroxide than with water except 980 mM. The results of the present research indicated that hydrogen peroxide had physiological and biochemical effects on the germination processes of alfalfa.
PEMETAAN MORFOLOGI DASAR PERAIRAN UNTUK PEMANTAUAN SEDIMENTASI DI DERMAGA PERIKANAN ULEE LHEU MENGGUNAKAN SINGLE BEAM ODOMETER DUA FREKUENSI
Authors: Rahmawan Guntur Adhi , Ondara Koko , Adnan Ilham 
Published: October 2021

ABSTRACTUlee Lheu Fishing Port Jetty is an important port in Banda Aceh City which functions as a crossing, loading and unloading port. The issue of sedimentation is the main problem. This study aims to determine the morphology of the seabed as the basis for monitoring sedimentation at the Ulee Lheu Fishing Port Jetty. Bathymetric surveys were carried out in the dock pool using a single beam echotrack odometer. Tides were obtained using the IOC Sea Level Monitoring for 29 days and analyzed using the admiralty method. The results of the processing showed that there was sedimentation in the area of the Ulee Lheu Fishing Port Jetty. The depth of the wharf pool ranges from 0-7,7 meters with a sediment volume of 250.117,15 m3. Meanwhile, the tidal water type is included in the double daily tidal type with a value of F = 0,15 and the tidal distance is 2,38 meters and is included in the micro tidal range category and there is sedimentation in the Ulee Lheu Fishing Port Jetty.Keywords: Bathymetry, sedimentation, morphology, Ulee Lheu Port, tidal rangeABSTRAKDermaga Perikanan Ulee Lheu merupakan pelabuhan penting di Kota Banda Aceh yang difungsikan sebagai pelabuhan penyeberangan maupun sebagai pelabuhan bongkar muat. Isu sedimentasi menjadi masalah utama di dermaga ini. Penelitian ini bertujuan untuk mengetahui morfologi dasar laut sebagai dasar pemantauan sedimentasi di Dermaga Perikanan Ulee Lheu. Survei batimetri dilakukan di kolam dermaga menggunakan echotrack odometer single beam. Pasang surut diperoleh menggunakan dari IOC Sea Level Monitoring selama 29 hari serta dianalisa menggunakan metode admiralty. Hasil pengolahan menunjukan terjadi sedimentasi di areal Dermaga Perikanan. Kedalaman kolam dermaga berkisar antara 0-7,7 meter dengan volume sedimen berkisar 250.117,15 m3. Sementara tipe pasang surut perairan termasuk dalam tipe pasang surut harian ganda dengan nilai F=0,15 serta jarak tunggang pasut sebesar 2,38 meter dan termasuk dalam kategori mikro tidal range dan terdapat sedimentasi di bagian Dermaga Perikanan Ulee Lheu.Kata Kunci : Batimetri, Sedimentasi, Morfologi, Dermaga Perikanan Ulee Lheu, tunggang pasang surut