bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modeling and Optimizing the Parameters of Condensers in Split Type Room Air Conditioners
Authors: Hasan Rahatul , Bahar Md Khairul , Alam Md Noor A , Ali Md Yasin , Choudhury MAA Shoukat 
Published: July 2021

Split type room air conditioners (RACs) are very common nowadays. In Bangladesh, RAC manufacturers employ trial-error prototyping techniques in their design to increase the efficiency of RACs and the profitability of the plant. Computer modeling can be a great help to reduce the cost in the R&D stage to find the optimum design of RACs. In this study, modeling of heat transfer in the condenser of split type RACs employing the techniques of Computational Fluid Dynamics (CFD) was performed. To reduce the computational load the geometry was divided into small sections and geometric symmetries were also taken into account. For the simulation, the geometry and other relevant data were set in such a way so that they commensurate closely with real industrial data. An example data set for validation of simulation results were obtained from an AC manufacturer company, Elite Hitech Industries Ltd. The geometry was built using meshing techniques. Copper and aluminum were selected as materials for tubes and fins, respectively. R-22 was chosen as the refrigerant. Heat transfer and fluid flow were modeled using non-isothermal flow in a multi-physics environment. The main assumptions employed are laminar flow, extra coarse mesh size, constant air inlet temperature, perfect insulation between system and surroundings, and thin layer fins. The temperature distribution and heat transfer efficiency in the condenser, the impact of different refrigerant flow arrangements in the tubes have been studied in detail. This study leads to the finding of efficient refrigerant flow arrangements from the viewpoint of maximum heat transfer.
Chemical Engineering Research Bulletin 21(2020) 20-25
Effect of Wood Saw Dust and Chopped Jute Fiber on the Tensile Properties of Epoxy Based Polymer Composite
Authors: Haque MS , Islam MA 
Published: July 2021

Polymer composites play a good role in various engineering applications because of their good combination of various properties such as unbeatable light weight, relatively high strength, ease of fabrication, corrosion resistance, high impact strength, design flexibility, dimensional stability, non-conductive properties, etc. So, polymer composites have attracted big attention from world-wide researchers. Epoxy based composite are largely used in load bearing application such as aerospace and automobile industries due to their good mechanical properties and corrosion resistance. In this research work, epoxy-based composites were developed by adding 5% wood saw dusts or 2 mm size chopped jute fibers. The jute fibers and saw dusts were added to gain some special property such as biodegradability. The developed composites were then characterized by tensile tests. Experimental results revealed that 5% saw dusts additions have no significant effect on the tensile strength of epoxy-based polymer composites. However, chopped jute fibers have been found to decrease the strength as well as fracture morphology noticeably.
Chemical Engineering Research Bulletin 21(2020) 94-98
Study of Fire Growth Behavior in a Residential Apartment using Fire Dynamic Simulator
Authors: Sakib Fahim Shahriar , Ahmed Riazuddin , Khan Easir A 
Published: July 2021

Fire accidents are very frequent and a major issue in Bangladesh in recent times. In this paper fire growth behavior in an apartment building is studied through a numerical analysis using Fire Dynamic Simulator (FDS). A model apartment with fixed combustibles was created using FDS. The fire growth characteristics were studied and heat release rate, the rise of temperature, toxic gas dispersion and human evacuation were assessed. The fire was generated using a burner function. Computational analysis results from those models were analyzed and discussed. The relationship of wind and ventilation effect with time helps to predict the fire growth behavior in different location of the apartment. Evacuation modeling was created to illustrate the effect of evacuation time and fractional effective dose (FED) for different types of agents. FED is the summation of toxic gas consumption which is important for safe evacuation. The results show that the ventilation effect releases the heat and makes the apartment less vulnerable. Elderly people took more time for total evacuation than other groups that related to FED percentage. The idea of critical door length is demonstrated for safe evacuation during fire emergencies.
Chemical Engineering Research Bulletin 21(2020) 99-105
Whole-Exome Sequencing Identified CFTR Variants in Two Consanguineous Families in China
Authors: Yang Binyi , Lei Cheng , Yang Danhui , Tan Zhiping , Guo Ting , Luo Hong 
Published: July 2021

BackgroundCystic fibrosis (CF) is an autosomal recessive disease caused by genetic variants of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. It is a common hereditary disease in Caucasians while rare in the Chinese. Until now, only 87 Chinese patients have been reported with molecular confirmations. The variant spectrum and clinical features of Chinese CF patients are obviously different from those of Caucasians.Materials and MethodsWhole-exome sequencing was applied to analyze the exome of three individuals who have only the typical CF phenotype in the respiratory system from two consanguineous families. The protein domain and structure analysis were applied to predict the impact of the variants. Sanger sequencing was applied to validate the candidate variants.ResultsA previously reported homozygous variant in CFTR (NM_000492.4: c.1000C &gt; T, p.R334W) was identified in proband I. A novel homozygous variant in a polymorphic position (NM_000492.4: c.1409T &gt; A, p.V470E) was identified in two individuals in the family II. The novel CFTR variant predicted to be disease-causing is the first, to the best of our knowledge, to be reported in CFTR. However, in vitro validation is still needed.ConclusionOur finding expands the variant spectrum of CFTR, reveals clearer clinical phenotype distinction and variant spectrum distinction between Chinese and Caucasian CF patients, and contributes to a more rapid genetic diagnosis and future genetic counseling.
Clinicopathologic Features and Risk Factors of Proteinuria in Transplant Glomerulopathy
Authors: Zhang Qiang , Budde Klemens , Schmidt Danilo , Halleck Fabian , Duerr Michael , Naik Marcel G. , Mayrdorfer Manuel , Duettmann Wiebke , Klauschen Frederick , Rudolph Birgit , Wu Kaiyin 
Published: July 2021

Background: Transplant glomerulopathy (TG) is one of the main causes of post-transplant proteinuria (PU). The features and possible risk factors for proteinuria in TG patients are uncertain.Methods: We investigated all patients who had biopsy-proven TG from 2000 to 2018 in our center. The clinical and histological data were compared between two groups with or without PU (cut-off = 0.3 g/day). Spearman correlation analysis was used to evaluate the relationship between PU and pathological changes. The risk factors for PU in TG patients were determined by multivariable logistic regression analysis.Results: One hundred and twenty-five (75.76%) of all enrolled 165 TG patients had proteinuria ≥0.3 g/day at the time of biopsy. TG patients' PU level was significantly correlated with Banff lesion score cg (ρ = 0.247, P = 0.003), and mm (ρ = 0.257, P = 0.012). Systolic blood pressure ≥140 mmHg (OR 2.72, 95% CI 1.04–7.10, P = 0.041), diastolic blood pressure ≥90 mmHg (OR 4.84, 95% CI 1.39–16.82, P = 0.013), peak PRA ≥5% (OR 6.47, 95% CI 1.67–25.01, P = 0.007), positive C4d staining (OR 4.55, 95% CI 1.29–16.11, 0.019), tacrolimus-based regimen (OR 3.5, 95% CI 1.28–9.54, P = 0.014), and calcium channel blocker usage (OR 4.38, 95% CI 1.59–12.09, P = 0.004) were independent risk factors for PU.Conclusions: Proteinuria is common in TG patients. systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg, peak PRA ≥5%, positive C4d staining, tacrolimus-based regimen, and calcium channel blocker usage are associated with proteinuria in TG patients.
Pseudocirrhosis in Breast Cancer – Experience From an Academic Cancer Center
Authors: Gopalakrishnan Dharmesh , Shajihan Ain , Purysko Andrei S. , Abraham Jame 
Published: July 2021

BackgroundPseudocirrhosis is characterized by radiological changes in the liver that resemble cirrhosis, but with more rapid onset and progression. Though reported most frequently in patients with metastatic breast cancer, little is known about its prognostic factors and impact on breast cancer outcomes.MethodsIn this observational study, we reviewed abdominal CT and/or MRI scan reports of all patients with invasive breast cancer diagnosed at our center, during a ten-year period, to identify patients with pseudocirrhosis. Exclusion criteria included lack of baseline imaging, pre-existing cirrhosis, hepatitis B or C, other chronic liver diseases, or heavy alcohol use. Routine descriptive statistical measures were used. Survival distributions were estimated using Kaplan-Meier method, and Cox regression was used for multivariate analysis. Two-tailed p &lt; 0.05 was considered significant.ResultsEighty-six patients were included – all were females, median age was 57.5 years, and 90% were Caucasian; 86% of primary tumors were hormone-receptor positive and 17% were HER2 positive. Most patients (98%) had metastatic disease with liver involvement (94%), and were heavily pre-treated – 97% with chemotherapy, 85% with hormonal therapy, and 19% with anti-HER2 agents. Median interval from breast cancer diagnosis to pseudocirrhosis was 75.4 months (IQR 35.2-115.3 months). Thirty-six percentage of patients had ≥1 signs of portal hypertension and 49% had ≥1 signs of hepatocellular failure. Pseudocirrhosis led to permanent discontinuation of chemotherapy, endocrine therapy, and all systemic therapies in 29%, 31%, and 20% patients, respectively. Median overall survival from diagnosis of pseudocirrhosis was 10.0 months (95%CI 5.2-14.8 months). On multivariate analysis, coagulopathy, hyperbilirubinemia, hypoalbuminemia, and cancer progression were independently predictive of mortality.ConclusionsIn this largest series, to date, of breast cancer with pseudocirrhosis, the latter was often complicated by portal hypertension and hepatocellular failure, and markedly impacted breast cancer management. Survival was shorter for patients who developed hepatocellular failure.
Development and Evaluation of the CASTLE Trial Online Sleep Intervention for Parents of Children with Epilepsy
Authors: Wiggs Luci , Cook Georgia , Hiscock Harriet , Pal Deb K. , Gringras Paul 
Published: July 2021

Introduction: Many of the sleep problems experienced by children with epilepsy (CWE) have the same behavioural basis as common sleep problems seen in typically developing (TD) children. Behavioural sleep interventions (BSIs) are widely used to treat these sleep problems in TD children and are hypothesised to be effective for CWE. However, specific considerations need to be addressed and incorporated into a BSI for CWE to ensure the intervention is tailored to this population's needs. This paper details developing and tailoring an online BSI for parents of CWE, to be used in the CASTLE (Changing Agendas on Sleep, Treatment and Learning in Epilepsy) Sleep-E clinical trial.Method: In phase one, two existing theory-driven paediatric BSIs were adapted into a novel online behavioural sleep intervention (CASTLE Online Sleep Intervention or COSI) which specifically incorporated the needs and requirements reported by nine parents of CWE. Scoping their needs included conducting interviews with three CWE so that they could contribute to the overall intervention content. In phase two, six of these parents evaluated COSI, reviewing and feeding back on COSI until parental approval for content and functionality was achieved.Results: In phase one, a range of adaptations was made to the content and presentation of standardised intervention material to acknowledge and emphasise the key seizure-specific issues to ensure COSI best met parents of CWE's needs. Adaptations included embedding parent and child experiences in the intervention, including particular information requested by parents, such as the links between sleep and seizures and managing child and parental anxieties around sleep, as well as developing functionality to personalise the delivery of content. In phase two, parents confirmed that they found the final version of COSI to be functional and appropriate (after one round of review) for use by parents of CWE and that 100% would recommend it to other families who have CWE.Discussion: It is hoped that the use of evidence-based BSIs, adapted to consider salient epilepsy-specific factors, will increase parent-engagement, COSI's relevance for this particular patient group and overall efficacy in improving sleep in CWE. The effectiveness of COSI will be tested in the CASTLE Sleep-E clinical trial (https://castlestudy.org.uk/).
Lay Public View of Neuroscience and Science-Based Brain Health Recommendations in Slovenia
Authors: Tomat Nastja , Perovnik Matej , Vidmar Gaj , van Midden Vesna , Fabjan Sara , Hawlina Hana , Trol Dolores , Holnthaner Alina , Krajnc Sebastijan , Grešak Maruša , Žerdin Liza , Vidmar Judita , Bresjanac Mara 
Published: July 2021

Background:Brain health is one of the cornerstones of a long and full life. Active care for brain health and reduction of lifestyle-related risks for brain disorders may be a key strategy in tackling the growing prevalence of mental and neurological illnesses. Public knowledge, perception, and preventive behavior need to be considered in the planning of effective strategies for brain health promotion. Our research is the first effort aimed at assessing Slovenian lay public knowledge, search and use of scientific information about the brain, and care for brain health.Methods:An online survey was used to gather data for descriptive and associative statistical analyses of a sample of the Slovenian public (n= 2568) in August 2017. Participants with formal brain-related education were excluded, leaving the remaining sample of the lay public (n= 1012). Demographic characteristics and information regarding the perceived importance and knowledge of brain health and engagement in preventive behaviors of participants were collected, and key associative analyses were carried out.Results:The majority of respondents (89%) considered brain health to be important. Over one-third (39%) considered their knowledge of the brain as sufficient relative to their needs. Most of the respondents identified science-recommended practices to be important for brain health. No recommendation was followed daily by the majority of the respondents, primarily due to declared lack of time (59%), and lack of information (32%). Information was obtained primarily from television (38%), followed by newspapers and magazines (31%), the Internet (31%), and direct conversations (27%). However, the highest-rated, preferred source of information was lectured by experts. One-third of our sample struggled with the trustworthiness of information sources. Female gender and older age were associated with a higher frequency of healthy practices. Personal or familial diagnoses of brain disorders were not associated with a higher frequency of the behavior in favor of brain health, but did affect available time and perceived value of preventive practices.Conclusions:Our research provides an initial insight into the perceptions, knowledge, and brain health-promoting behavior of the Slovenian lay public. Our findings can inform future strategies for science communication, public education and engagement, and policy-making to improve lifelong active care for brain health.
Hubungan Motivasi Memasuki Dunia Kerja dengan Kesiapan Kerja Siswa Kelas XII Teknik Komputer dan Informatika
Authors: Fitria Linda , Kurniawati Dita 
Published: July 2021

Penelitian ini bertujuan untuk mengetahui Hubungan Motivasi Memasuki Dunia Kerja dengan Kesiapan Kerja Siswa Kelas XII Teknik Komputer dan Informatika SMK N 2 Padang. Penelitian ini merupakan penelitian kuantitatif. Populasi adalah siswa kelas XII Teknik Komputer dan Informatika SMK Negeri 2 padang pada tahun pelajaran 2014/2015 dengan jumlah 47 orang. Instrumen yang digunakan untuk mengumpulkan data dalam penelitian ini adalah kuesioner. Teknik analisa data yang digunakan dalam penelitian ini yaitu uji normalitas, uji linearitas, serta uji hipotesis. Berdasarkan hasil penelitian yang telah dilakukan, dapat diambil kesimpulan bahwa Terdapat hubungan yang signifikan antara motivasi memasuki dunia kerja dengan kesiapan kerja siswa kelas XII Teknik Komputer dan Informatika SMK N 2 Padang sebesar 3,760. Ini dapat disimpulkan bahwa semakin tinggi motivasi memasuki dunia kerja maka makin tinggi pula kesiapan untuk bekerja.
STUDY OF THE PECULIARITIES OF FORMING THE CREATIVE POTENTIAL IN PROSPECTIVE NURSES IN THE COURSE OF PROFESSIONAL TRAINING
Authors: Dubasenyuk О. , Voznyuk О. , Kovalshuk T. 
Published: July 2021

The article analyzes the process of forming the creative potential in prospective nurses in the course of professional training. The main reason for the existing problems connected with forming the creative potential in prospective nurses lies in the predominance in the students the external motives for choosing a profession since a significant number of the prospective nurses lose interest in the profession in the educational process. This takes place due to the imperfect methods, tools and forms used in the professional training in the educational institution. Other reasons of this situation are connected with the small number of practical activities, imperfections and outdated content of educational material. This, in turn, leads to a reproductive style of thinking and low cognitive motives in the perspective nurses when they do not want to develop pertinent skills and abilities, to improve their personality due to low level of inquisitiveness and weak persistence in achieving the goals.
It is proved that modern requirements to professional functions and social role of specialists in the sphere of nursing activity necessitate the modernization of the educational environment for the prospective competitive nurses. This presupposes the creation of innovative systems of professional development with taking into account the changes and consequences of their impact on professional activities of the prospective nurses. This can be realized by implementing a special course "Skills and professional inspiration of a nurse", designed to train the prospective nurses in the 5th semester.
It is established that one of the effective directions of developing the creative potential in the prospective nurses is related with updating the prospective nurses' professional training through the introduction of innovative educational technologies and interactive teaching methods into the educational process.
It is also found out that the reform of professional and professional before-higher education determines the tendency to actualize individualized training in medical institutions concerning self-development of specialists' personality in the context of their future professional activity, as well as forming individual psychological qualities, professionally significant qualities in all participants in the educational process, providing opportunities for individual research activities, improving the educational process in different types of medical institutions. To accomplish this, the prospective specialist must turn from an object of educational influence into a subject whose main features are activity, individuality and independence. This, in turn, presupposes the integration of the students into the creative educational environment of the educational institution, strengthening its development capabilities as a complex of systematized innovative educational resources with pertinent methodological, technological, organizational support.
COMPETENCY-BASED APPROACH AND SOFT SKILLS IN MODERN EDUCATIONAL PARADIGM
Authors: Diachenko N. , Usatyi A. 
Published: July 2021

The article presents the results of the search for optimal forms of cooperation between teachers and students in the context of the COVID-19 pandemic and distance learning. New realities require teachers to react quickly, make extraordinary decisions and take adequate action for the proper functioning of the education system. The expediency of using the competence approach and interactive teaching methods in the distance educational process is substantial. The dynamics of the use of e-learning elements in Ukrainian higher education institutions is trace in the dynamics, the advantages and disadvantages of this form of education are noted.
Modern education should ensure the formation and comprehensive development of a spiritually rich person who not only has a holistic system of scientific and practical knowledge, but also able to realize themselves according to their own aspirations and abilities, able to navigate the rapid flow of information, has a high culture of thought, social relations and communications. Therefore, one of the important tasks of education is the formation of soft skills. They help to achieve success in life, to find a reasonable balance between academic knowledge and practical skills. The peculiarities of soft skills formation during distance learning are clarify.
It is proposed to involve not only teachers, but also all stakeholders, first of all – students, from whom a lot of good advice can be heard. An example of a modern vision of the role of a teacher and a set of his/her qualities necessary for the successful organization of the educational process from the point of view of the student is presented. Such qualities include high level of knowledge, involvement in professional communities, ability to learn throughout life, use of the latest technologies, participation in social networks, stress resistance, ability to recover from stress, love of the profession and a certain sacrifice.
IMPACT OF MERCURY CHLORIDE EXPOSURE ON SOME OF IMMUNOLOGICAL AND BIOCHEMICAL ASSAYS OF COMMON CARP, CYPRINUS CARPIO
Authors: Mustafa S. A. , Al-Rudainy A. J. 
Published: July 2021

This work was designed to evaluate the influence of mercury chloride on some of biochemical and immunological biomarkers in common cap, Cyprinus carpio. Around of 120 fish were randomly allocated into four groups (30 fish per group) in triplicates as follows; first group act as control group provided with water only without adding HgCl2; G1, G2 and G3 were exposed to waterborne HgCl2 at levels of 0.01, 0.05 and 0.1 mg l-1 respectively. After one month exposure to HgCl2, there were significantly decreased (P<0.05) in lymphocyte transformation index and in phagocytic and lysozyme activities. Besides, biochemically, Albumin and globulin content exhibited significantly declined (P<0.05) particularly at higher dose of HgCl2. In contrast, blood glucose value and urea showed significantly increased (P<0.05) especially in G3. On the other hand, variable changes were observed in total count of leucocytes included lymphopenia and neutrophilia in G1 and G2 compared to control. In conclusion, this investigation indicated that mercury chloride has immune suppressive effects and is extremely toxic to common carp.