bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sykepleievitenskap ved universitet i Bergen opkomst 1979 – og afviklet 2019/2020.
Authors: Petersen Karin Anna 
Published: November 2021

Abstract:
Artiklen præsenterer descriptivt oprettelse og nedlægglese af faget Sykepleievitenskap ved universitet i Bergen (UIB). Sykepleievitenskap konstituerede 1979 med et professorat i Bergen, det første i Norden, og institutt for højere sykepleirutdanning oprettedes. UIB er det eneste sted sykeplejersker på Vestlandet har haft mulighed for at blive skolet i grundvidenskaplige teorier, begreber og metoder og aflægge eksamen på master- og ph.d niveau i studier om sykepleie. UIB har 2019 nedlagt studietilbudet. Efter en lang planlæggelse og oprettelsesproces siden 1960’årerne, begyndte nedlæggelse gradvis i 2003, da Sykepleievitenskap gik fra at være et autonomt fag md en egen logik til at blive en studieretning, og fra at organiseringen var på et eget institut som forvandles til en seksjon, senere faggruppe- (sykepleievitenskap) og forskninggrupper, og til sidst helt at forsvinde når instituttet forvandler organisering af helsefag i fagområder (flere helsefag undtagen sykepleievitenskap og fysioterapivitenskap) og etablerer undervisningsgrupper (pluralis for flere fag). Sykepleievitenskap gik fra hovedfag, til mastergrad i helsefag med studieretning sykepleievitenskap til at ophøre helt som fag ved UIB. Og en ny grad: Master i helse og samfunn – oprettes - ordet vitenskap er fjernet fra titlen (man fastholder 3 studieretninger: genetisk, yrkeshygiejne, Ulike perspektiv på sentrale helseutfordringar), ligesom Manuel terapi fortsat findes ved institutionen. (tabell 1). De studieretninger som understøtter den dominante majorprofession medicin opretholdes og udvikles, mens de to studieretninger, sykepleievitenskap 1978/1979 og fysioterapivitenskap 1991, som etableredes som autonome fag med egne logikker, og fik institutionel tilknytning for sygepleje først til samfundsvidenskab og medicin, siden alene til det medicinske fakultet, afvikles og absentreres.
Impact of Coastal Flood on Building, Infrastructure, and Community Adaptation in Bukit Bestari Tanjungpinang
Authors: Hanif Muhammad , Putra Beben Graha , Hidayat Rizki Atthori , Ramadhan Ravidho , Ahyuni Ahyuni , Afriyadi Afriyadi , Wan Moh Jaafar Wan Shafrina , Hermon Dedi , Mokhtar Ernieza Suhana 
Published: November 2021

Coastal flood in Indonesia, namely as banjir rob, is a phenomenon that increases seawater to inundate around the tidal area. In Tanjungpinang, cases of coastal floods become a serious problem for people living in this area. This research aims to model the coastal flood inundation by modeling water inundation with a maximum level increase scenario. Its model was used to estimate coastal floods' impact on houses, buildings, and infrastructures with scenario 2 meters of sea-level rise. On the other hand, the budget loss for restoration was estimated to study the effort of community adaptations with the ECLAC RAB method and observation to understand community adaptation. It was found that the spatial model succeeded in zoning inundation areas, which had a significant impact on houses, buildings, worship places, schools, and industrial at many 4112 units. From this case, the budget loss for the restoration of the physical environment was estimated at around 61994014.75 USD. In addition, the survey revealed the existing condition before and after the coastal flood. Several community efforts for adaptation were developing houses on stilt and hoarding the lowest land on-site location for build houses.
THE ACTION OF FOOTBALL SUPPORTERS IN SUSTAINING SPORTS STADIUM
Authors: Anshari Faridhian 
Published: November 2021

ABSTRACT The sports stadium is an important element in organizing a football match. From a number of negative cases related to the behavior of football supporters in Indonesia, the story of the destruction of stadium facilities by the supporter is quite often become the headline in various media. One of the major events that occurred was the destruction of the Gelora Bung Karno National Stadium (GBK) facilities in the 2018 Presidential Cup final by some individuals who were thought to be supporters of the Persija Jakarta club. The biggest problem is, the stadium facilities are still in trial after renovation and will be prepared for the 2018 ASIAN Games. Encouraged by the guilty pleasure, Jakmania as Persija Jakarta's Supporters took an independent initiative by raising the #JagaGBK movement without any interference with the club's managerial. The purpose of this campaign is to maintain the surrounding environment and sports facilities inside the GBK stadium. This grassroots movement involves all Jakmania who are estimated around 45,000 people from 66 Regional Coordinators. The purpose of this study is to understand the use of campaign techniques carried out by Jakmania in performing the #JagaGBK campaign. This study used a qualitative approach with data collection techniques through in-depth interviews with three resource persons: the main chairperson of Jakmania, the Jakmania board of trustees, and the Head of branch Jakmania East Jakarta. This research resulted in findings related to strategies in assembling member participation, similarity goal associations, efforts to unite (integrative), giving rewards, delivering messages, gaining empathy, and giving coercion to members who are not involved in running #JagaGBK campaigns. This research is expected to find a formulation that can be an inspiration for other campaigns which held by the football supporters, specially regarding environmental preservation and the sports facilities.Keywords: Supporters, Football, Campaign #JagaGBK, Jakmania, and Persija Jakarta.
Pengaruh Faktor Komunikasi, Sumber Daya, Disposisi dan Struktur Birokrasi dalam Implementasi Kebijakan Pelayanan Kesehatan Tradisional Integrasi Terhadap Penyelenggaraan Pelayanan Kesehatan Tradisional di Puskesmas
Authors: Riswandi Agus 
Published: November 2021

AbstractRencana Strategis Kementerian Kesehatan Republik Indonesia Tahun 2015 - 2019 telah menetapkan indikator pencapaian target penyelenggaraan pelayanan kesehatan tradisional, yaitu jumlah puskesmas yang menyelenggarakan pelayanan kesehatan tradisional dan rumah sakit pemerintah yang menyelenggarakan pelayanan kesehatan tradisional. Dengan demikian kebutuhan layanan kesehatan secara terintegrasi sangat dibutuhkan di berbagai wilayah secara terintegrasi di masing-masing puskesmas, termasuk di Cimahi. Dalam penelitian ini dirumuskan untuk menjawab rumusan masalah yang mencakup: (1) Seberapa besar pengaruh faktor komunikasi dalam Implementasi Kebijakan Pelayanan Kesehatan Tradisional Integrasi terhadap Penyelenggaraan Pelayanan Kesehatan Tradisional di Puskesmas di Kota Cimahi?; (2) Seberapa besar pengaruh faktor sumberdaya dalam Implementasi Kebijakan Pelayanan Kesehatan Tradisional Integrasi terhadap Penyelenggaraan Pelayanan Kesehatan Tradisional di Puskesmas di Kota Cimahi?; (3) Seberapa besar pengaruh faktor disposisi dalam Implementasi Kebijakan Pelayanan Kesehatan Tradisional Integrasi terhadap Penyelenggaraan Pelayanan Kesehatan Tradisional di Puskesmas di Kota Cimahi?; (4) Seberapa besar pengaruh faktor struktur birokrasi dalam Implementasi Kebijakan Pelayanan Kesehatan Tradisional Integrasi terhadap Penyelenggaraan Pelayanan Kesehatan Tradisional di Puskesmas di Kota Cimahi?. Penelitian dilakukan di wilayah Kota Cimahi dengan metodologi yang digunakan dalam riset ini menggunakan pendekatan kuantitatif dengan analisis data Path Diagram untuk menguji hipotesis. Riset ini menghasilkan temuan bahwa Faktor komunikasi telah memberikan pengaruh yang tinggi dalam Implementasi Kebijakan Pelayanan Kesehatan Tradisional Integrasi terhadap Penyelenggaraan Pelayanan Kesehatan Tradisional di Puskesmas di Kota Cimahi. Adapun faktor sumberdaya, faktor disposisi, faktor struktur birokrasi memberikan pengaruh yang sedang terhadap Implementasi Kebijakan Pelayanan Kesehatan Tradisional Integrasi terhadap Penyelenggaraan Pelayanan Kesehatan Tradisional di Puskesmas di Kota Cimahi.Kata Kunci: komunikasi; sumber daya; disposisi; struktur birokrasi; kesehatan tradisional
Survival of patients with metastatic bladder cancer in the Russian Federation: results of a multicenter registry study URRU
Authors: Tsimafeyeu I. V. , Alekseeva G. N. , Petkau V. V. , Zukov R. A. , Mazhbich M. S. , Semenov A. V. , Statsenko G. B. , Novikova O. Yu. , Zaytsev I. V. , Popova I. L. , Gurina L. I. , Mukhina M. A. , Vladimirova L. Yu. 
Published: November 2021

Background. Data on the overall survival (OS) of patients with metastatic bladder cancer (BCa) is rarely published.The objective of the URRU register study is to assess OS and collect information on the administration of different treatments in patients with metastatic BCa in routine clinical practice in Russia.Materials and methods. Patients were retrospectively identified in 9 oncology centers in different regions of Russia and included in the study if they were diagnosed with metastatic BCa between January 2017 and January 2018. We collected anonymized data online, including demographic characteristics of patients, details of their therapy, and outcomes.Results. This study included 246 patients. Their mean age upon the diagnosis of metastatic BCa was 72 years with 60.6 % of patients over 70 years of age. The proportion of males was 74.8 %. The histological subtype of BCa (urothelial carcinoma, etc.) was identified in 70.3 % of cases. Ninety-two patients (37.4 %) received pharmacotherapy. The most common treatment option was chemotherapy (76 %); the most common drug combination was gemcitabine and cisplatin (41.3 %). Immunotherapy was used in 19.6 % of patients; 13.6 % of participants received more than two lines of therapy. Three-year OS rate was 10.6 %; median OS was 7 months (95 % confidence interval (CI) 5.4-8.6). Patients receiving systemic therapy demonstrated significantly longer survival than those receiving no therapy (21 months; 95 % CI 17.38-24.62 vs 3 months; 95 % CI 1.79-4.22; p <0.0001). Patients receiving immunotherapy had better survival than individuals receiving chemotherapy (median OS 34.5 months vs 18 months; p = 0.003).Conclusion. The survival rates in the URRU study were relatively low, which can be attributed to the fact that only one-third of patients received pharmacotherapy and very few patients received immunotherapy. Second and subsequent lines of therapy were rarely used in patients with progressive disease. The implementation of novel treatments, including immune checkpoint inhibitors, will increase the survival of BCa patients.
Surgical treatment of giant renal tumor: a case report
Authors: Latypov V. R. , Popov O. S. , Novikov S. I. , Latypova V. N. , Ahmedov D. B. 
Published: November 2021

Renal tumors account for 2 to 3 % of all malignant tumors in adults. Of all patients with renal cell carcinoma, 30 to 40 % have advanced forms of the disease. In the literature, the term "giant renal tumor" is used for tumors larger than 20 cm. In this article, we report a case of surgical treatment for a giant malignant kidney tumor.Patient N., female, 54 years old, referred to an outpatient clinic with complaints of a change in the shape of the abdomen on the left with a palpable large tumor, abdominal pain, shortness of breath, weakness, constipation, episodes of blood in the urine and increased blood pressure. Body mass index 30.2 kg/m2. Ultrasound examination revealed a large tumor in the left retroperitoneal space. Laboratory testing of blood, urine was performed, findings were unremarkable. According to the data of magnetic resonance imaging, the left kidney was transformed into a large cystic solid formation, measuring 30.5 х 17.5 х 17.0 cm, heterogeneously accumulating a contrast agent with a solid component. Patient was admitted to the urology department for surgical treatment. We performed radical nephrectomy on the left with thoracolumbar laparotomy access on the left with resection of the 10th rib, resecting the renal tumor with the adrenal gland, total weight of the complex was 10.7 kg. The histological structure was determined as poorly differentiated renal carcinoma with invasion of the perinephric tissue. In the adrenal gland, fields of fresh erythrocytes with an admixture of tumor tissue were noted. Examined lymph node tissue was completely replaced by tumor cells. Postoperative period was characterized by episodes of dynamic intestinal obstruction. The patient was discharged from the department in a satisfactory condition on the 13th day after the operation, but died 1.5 months after discharge, the cause of death has not been established, as no autopsy was performed. Thus, the size of the tumor is not a contraindication to surgical treatment, which improves the survival rate of patients with malignant renal tumors.
Irene Joliot-Curie, Frederic Joliot-Curie
Authors: Karyakin O. B. 
Published: November 2021

Irene Joliot-Curie is the daughter of Marie Curie, a double Nobel Prize-winner. In 1925, Irene Curie became Doctor of Science.In 1926, Irene married her colleague Frederic Joliot, an assistant at the Radium Institute. With him, she continued experiments with various chemical elements. In some of these experiments, Irene and Frederic performed bombardment of boron, and aluminium with alpha particles, thereby producing new chemical elements. These new elements were radioactive: aluminum became radioactive phosphorus, while boron became a radioactive isotope of nitrogen. Within a short time, Joliot-Curie created many new radioactive elements. In 1935, Irene and Frederic Joliot-Curie were jointly awarded the Nobel Prize for Chemistry for their artificial creation of new radioactive elements Working with uranium in the late 1930s, Irene Joliot-Curie made several important discoveries and came close to the discovery of uranium decay, when bombarded with neutrons.Jean Frederic Joliot was born in Paris, in the family of a prosperous merchant Henri Joliot and Emilia (Roederer) Joliot, who came from a wealthy Protestant family from Alsace.Frederic obtained his Doctor of Science degree in 1930 for a thesis on the electrochemistry of radioactive polonium. Having received the Nobel Prize in 1935 together with his wife, 35-year-old Frederick still remains the youngest Nobel Laureate in Chemistry.The discoveries and achievements of the Joliot-Curie family laid the foundation for further research in nuclear physics, chemistry, and nuclear medicine. Without their discoveries, it is impossible to imagine modern science and everyday life.
Experience of using 1<sup>st</sup> line combination immunotherapy in patients with metastatic renal cell carcinoma
Authors: Kalpinskiy A. S. , Myslevtsev I. V. , Andrianov A. N. , Nyushko K. M. , Golovashchenko M. P. , Vorobiev N. V. , Chertkova Ya. L. , Shirukova I. Kh. , Usanova E. Yu. , Alekseev B. Ya. 
Published: November 2021

The study objective is to evaluate effectiveness and tolerability of 1st line combination immuno-oncological therapy with nivolumab and ipilimumab in patients with metastatic renal cell carcinoma (mRCC) in clinical practice.Materials and methods. The study included 38 patients with mRCC who received combination immunotherapy between July of 2019 and September of 2021. Median follow-up duration was 8 (2-25) months. Mean age of the patients was 58.3 (20-85) years. Previously 22 (57.9 %) patients underwent surgical treatment. Unfavorable physical status 2-3 per the ECOG scale was observed in 10 (26.3 %) patients. Clear-cell type of renal cell carcinoma was diagnosed in 34 (89.6 %) patients, non-clear-cell types in 4 (10.4 %). Sarcomatoid component in the tumor was detected in 8 (21.0 %) patients. G3-4 mRCC variant was verified in 16 (42.1 %) patients. Poor prognosis per the IMDC (International Metastatic Renal Cell Carcinoma Database Consortium) scale was identified in 16 (42.1 %) patients, intermediate -in 20 (52.6 %) patients. All 4 administrations of combination immunotherapy were received by 29 (76.3 %) patients.Results. For median follow-up duration of 8 (2-25) months, 23 (60.5 %) patients continue treatment, 15 (39.5 %) completed therapy with nivolumab and ipilimumab due to various reasons including progression in 11 (28.9 %), death in 2 (5.3 %), intolerable toxicity in 2 (5.3 %) cases. Median duration of combination immunotherapy was 9 (2-24) months. Subsequent antitumor therapy was administered to 3 (7.9 %) patients. During induction course immune-mediated adverse event (grade III-IV hepatitis) developed in 3 (7.9 %) patients. Adverse events were observed in 81.6 % of patients, including grade III-IV in 23.7 % of patients. Objective response was observed in 44.8 % of cases, complete response in 5.3 % of cases, partial response in 39.5 % of cases; controlled disease was achieved in 84.3 % of patients. Median progression-free survival and overall survival were 8 months.Conclusion. In our study despite large number of patients with poor prognosis and poorly differentiated tumors, 64.0 % of patients are alive and 60.5 % of patients continue treatment without disease progression after 18 months of combination immunotherapy. Progression-free survival was significantly affected by sarcomatoid component in the tumor, number of unfavorable factors per the IMDC scale, best response per RECIST 1.1; overall survival was significantly affected by sarcomatoid component in the tumor, sum of measurable lesions, number of unfavorable factors per the IMDC scale, best response per RECIST 1.1, and presence of symptomatic metastases in the brain.
The clinical aspects of peritonitis developing after cystectomy
Authors: Krasny S. A. , Shishlo I. F. 
Published: November 2021

Background. Surgical morbidities of radical cystectomy, which are, as a rule, complicated intraabdominal infections, appear to be the main causes of repeated surgeries and fatal outcomes. The elimination of the infection Indus and an-timicrobic therapy are the currently accepted standard of treatment for postoperative peritonitis in cancer urology, as well as in general surgery hospital.Objective: defining the most reasonable option of surgical aid for peritonitis developing after cystectomy.Materials and methods. In the time period from 2000 through 2014, 58 cancer patients with postoperative peritonitis developing after cystectomy received indoor treatment at N.N. Alexandrov Republican Research and Practical Center for Oncology and Medical Radiology. Their mean age was 64.9 years, the range 44-90 years, 53 (91.4 %) of them being male. Primary urinary bladder cancer was present in 51 (87.9 %) patients. Peritoneal infection was microbiologically verified in 57 (98.3 %) patients. Each case of fatal outcome was associated with ineffective treatment of peritonitis. Depending on the intraoperative findings (presence or absence of a hollow organ defect) and the surgical approach undertaken (obstructive resection or operation maintaining the continuity of the intestinal and/or urinary tract), the patients were stratified into three groups: group 1 (n = 28), group 2 (n = 20) and group 3 (n = 10). There were no significant differences in the basic parameters specifying peritoneal infection severity between the patients of groups 1 and 2 vs group 3 (p >0.05).Results. Overall mortality amounted to 25.9 %, 15 patients died. Among the 28 (48.3 %) patients (group 1) who underwent obstructive elimination of the peritonitis focus by means of urointestinal reservoir ablation, resection of small or large intestine with ileo- or colostomy, 6 patients died, mortality 21.4 %. In the 10 (17.2 %) patients (group 3) who succeeded in preserving the urinary conduit or continuity of the bowels by anastomosis defect closure, resection of enteroentero-anastomosis or urointestinal reservoir with repeated anastomosing or defect closure, mortality was higher (60 %) (p = 0.045); 6 patients died.Conclusion. The most effective option of surgical treatment of postoperative peritonitis developing after cystectomy is obstructive reoperation on the bowels and urinary tracts: compared with the intervention consisting in preserving the urinary conduit and/or continuity of the intestinal tract, this type of surgery caused a 2.8-fold lower mortality.
Prevention and treatment of thrombosis in cancer and oncohematological patients
Authors: Somonova O. V. , Elizarova A. L. , Davydova T. V. 
Published: November 2021

The purpose of the review is to highlight the current possibilities for the prevention and treatment of venous thrombotic complications in patients with cancer.The data of 52 scientific sources published in the Russian and foreign press in 1997–2020 are considered.Cancer patients are at high risk of thrombotic complications, which worsen the outcome of anticancer treatment and are one of the leading causes of death. Thrombosis in an oncological patient increases the risk of death by 30 times, which is associated with fatal thromboembolism and a more aggressive course of the disease. The leading role in the pathogenesis of thrombotic complications is played by disorders in the hemostasis system caused both by the tumor itself and by therapy. Low molecular weight heparins are considered the basis for specific prophylaxis of thromboembolic complications in cancer patients. The use of low molecular weight heparins after surgery and during chemotherapy effectively reduces the incidence of venous thrombosis. Direct oral anticoagulants are promising drugs for oral administration and are indicated as one of the treatment options for patients with tumor-associated thrombosis with a low risk of bleeding and no drug interactions with ongoing systemic chemotherapy.