bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality of Radar Direction-Finding via Conical Scanning
Authors: Pluzhnikov A. D. , Kogteva L. V. , Pribludova E. N. , Sidorov S. B. , Chuzhaykin E. G. 
Published: November 2021

Introduction. Conical scanning is applied for optimizing hardware resources in new devices, as well as when upgrading existing systems. All this explains the relevance of studying this type of direction finding systems.Aim. To adjust and complement the known calculation relations for the variance of direction finding results – an indicator of the quality (accuracy) of direction finding, as well as to determine the possibilities of optimizing direction finding and automatic object tracking processes.Materials and methods. Factors limiting the accuracy of direction finding via conical scanning were analyzed using spectral analysis. Mathematical modeling followed by statistical processing of quantitative results makes it possible to determine the conditions under which the influence of certain factors is predominant, as well as the conditions under which adjustment (completion) of the known calculation relations is required. The specified conditions are the errors at which the objects of direction finding are tracked. New calculation relations for the mentioned adjustment were determined by the methods of statistical radio engineering.Results. The validity of the calculation relations found is confirmed by mathematical modeling. Calculations and modeling lead to the need to optimize parameters for automatic object tracking systems.Conclusion. The study shows that, when choosing parameters for auto-tracking systems with conical scanning, it is important to implement object tracking not with minimal, but rather with optimized tracking errors in angular coordinates, which are to be estimated during direction finding. Moreover, the optimized errors (the values of static errors and the most probable values of the dynamic tracking errors) will require adjustment of the known analytical estimates for the variance of the direction finding results – the qualitative indicator of the direction finder (accuracy indicator). The determined analytical relationships allow such an adjustment to be performed, leading to an increased variance estimate by 10 dB.
Modeling of the Scattering Field of an FGM-148 Javelin Anti-Tank Missile in Altair Feko
Authors: Kupryashkin I. F. , Zavodskyh K. Yu. 
Published: November 2021

Introduction. Computer-aided design systems for microwave devices are an effective tool for assessing the backscattering characteristics of complex-shaped objects. However, these calculations are often associated with significant computational costs, especially at large values of the ratio of the characteristic dimensions of the object to the wavelength. The use of asymptotic methods in combination with the mesh coarsening of object partition can significantly reduce these costs. However, in each practical case, this leads to a deterioration in the accuracy of the estimates obtained, which is hard to predict.Aim. Comparative assessment of the results of modeling the scattering field in the CAD of microwave devices using various methods for calculating and detailing the object model in the decimeter and centimeter wavelength ranges.Materials and methods. The research object was an anti-tank guided missile FGM-148 Javelin. The scattering field of Altair FEKO microwave devices was modeled in CAD using the methods of moments and physical optics in the frequency range from 1 to 10 GHz and angles from 0 to 180°. A comparison of one-dimensional backscatter diagrams and radar images obtained using these methods was carried out.Results. For the class of objects under consideration, the method of physical optics provides acceptable accuracy at frequencies of 5 GHz and higher with a step of partitioning the model surface of the order of one centimeter and a total calculation duration of the order of several minutes (Intel Core i5-4460 PC / 3.2 GHz / 8 MB RAM). At lower frequencies, acceptable accuracy and a similar calculation duration are achieved when calculating by the method of moments and a partitioning step of about 20 cm. The possibility of using the Altair FEKO CAD system for modeling radar images of objects with a resolution of at least 20 cm is demonstrated.Conclusion. The results obtained complement the well-known studies in the field of comparative assessment of the time and accuracy characteristics of various methods for calculating the scattering field of objects in the CAD of microwave devices.
KLASIFIKASI TINGKAT KEMATANGAN BUAH CARICA MENGGUNAKAN FUZZY LOGIC
Authors: Mahmudati Rina 
Published: November 2021

Buah carica adalah salah satu ciri khas kota Wonosobo, dimana banyak dijumpai di dataran tinggi Dieng. Selain teksturmya yang kenyal, mempunyai aroma yang segar juga memiliki kandungan serat yang tinggi untuk membantu melancarkan proses pencernaan serta mengandung Vitamin C dan E sehingga baik untuk kesehatan kulit. Carica memiliki rasa yang manis asam dan bagian kulit mengandung banyak getah sehingga kurang enak jika dikonsumsi secara langsung. Masyarakat setempat biasa mengolah buah carica menjadi keripik oven, manisan, sirup, dodol, selai dan menjadikannya sebagai usaha baik usaha rumahan mandiri maupun usaha kelompok yang tergabung dalam UKM. Aneka olahan tersebut berbahan baku buah carica, namun dengan tingkat kematangan yang berbeda. Masyarakat pengolah carica seharusnya memiliki kemampuan dalam membedakan kematangan buah carica, agar dapat menghasilkan produk makanan dengan rasa yang lezat. Namun, sebagian besar pengolah carica masih banyak yang belum bisa mengetahui tingkat kematangan buah dengan tepat, mereka hanya melihat kematangan dari warna buah dan aroma yang muncul dari buah carica. Penelitian ini bertujuan untuk merancang suatu program untuk mengetahui tingkat kematangan buah carica dengan menggunakan logika fuzzy. Uji coba program telah dilakukan dan mencapai hasil bahwa dengan menggunakan metode logika fuzzy dan program sederhana dengan bahasa pemrograman python dapat digunakan untuk mengklasifikasikan tingkat kematangan buah carica
Travesía até 'Mar maior': contexto literario e biográfico do primeiro Manuel María
Authors: Fernández Rial Rosalía 
Published: November 2021

Este artigo presenta un percorrido bio-bibliográfico a través dos sete libros de poemas publicados polo poeta Manuel María na década que abrangue desde os anos 50 até comezos dos 60. Dun xeito máis específico céntrase nos títulos seguintes: Muiñeiro de brétemas (1950), Morrendo a cada intre (1952), Advento (1954), Terra Chá (1954), Documentos persoais (1958), Libro de pregos (1962) e Mar Maior (1963).
O enfoque adoptado fundaméntase no concepto de intertextualidade acuñado por Bajtín e establece certos vínculos literarios entre os libros citados e outras obras co fin de que esas relacións nos permitan afondar na comprensión da escritura do autor protagonista ao tempo que dilucidan aspectos do contexto vital e literario onde Manuel María se insire no período referido.
Finalmente, cómpre aludir a que o modo de expresión empregado para transmitir os citados contidos se sitúa nun estilo literario e cunha tendencia ao simbólico e metafórico, sen perder o rigor inherente ao ámbito académico e ao eido da investigación filolóxica.
obra narrativa de Manuel María ou como contar a vida a través do río da escrita
Authors: Queixas Zas Mercedes 
Published: November 2021

Manuel María comparaba a súa obra literaria cun río, unha canle firme á que abeiraban e reatroalimentaban múltiples augas afluentes. Velaquí a raíz que sustenta unha obra narrativa que, inaugurando a década dos 50 do pasado século, abrangue máis de sesenta relatos que nacen e medran, en paralelo, á expresión escrita máis popular e recoñecida, a poética, mais tamén á dramatúrxica e ensaística.
Porque se a obra é río tamén é camiño en Manuel María, pois tanto na vida como na obra, sempre de mans dadas, procurei andar os camiños que a vida puxo diante de min.
última encrucijada: Emilia Pardo Bazán ante la Gran Guerra
Authors: Burdiel Isabel 
Published: November 2021

Este artículo tiene como objetivo analizar la posición de Emilia Pardo Bazán en el debate entre aliadófilos y germanófilos en España durante la I Guerra Mundial. Su defensa de una postura neutral en el conflicto creo que debe entenderse, más allá de las sin duda importantes preferencias personales y consideraciones de oportunidad, como parte de su proyecto de ampliar las nociones partidistas de qué cosa era lo político. Para tratar esta cuestión analizo la imbricación entre su lenguaje feminista, nacionalista y estético.
Leopoldo Alas y las mujeres robinsonianas: “La leyenda de oro”
Authors: Dupont Denise 
Published: November 2021

Este artículo trata varios dúos creados por Leopoldo Alas alemparejarse como autor o personaje con una mujer – literata, santa o no. Teniendo en cuenta la tendencia clariniana a aludir jocosamente a su propia impotencia, vejez o debilidad cuando dialoga con una interlocutora femenina, el artículo analiza una serie de textos que Alas publicó en la primavera de 1897 en La Ilustración Española y Americana, que luego salió en la última colección de ensayos de Clarín, el póstumo Siglo pasado (1901), con el título de “La leyenda de oro: un nuevo capítulo de la vida de San Francisco de Asís, por Pablo Sabatier (en francés). París, 1896”. Aunque parezca que va a ser una reseña, “La leyenda de oro” es más cuento que otra cosa, siendo un intercambio epistolar entre Elíseo, el narrador (un hombre mayor y culto, que se asemeja a Clarín) y una joven que se llama Elisena. Emilia Pardo Bazán sirve como tela de fondo para el cuento, ya que la joven protagonista primero se presenta como muy diferente de la autora coruñesa, pero luego imita la independencia de criterio de la que en un momento era muy amiga de Clarín, pero que ha dejado de serlo. Si a Clarín le gusta competir con mujeres fuertes e independientes, también le atrae la idea de que recen por él, y al final Elíseo le pide ayuda a Elisena, orientándola hacia ese cometido de apoyo espiritual.
‘La maga primavera’, un cuento impreso en vida de Pardo Bazán
Authors: Patiño Eirín Cristina 
Published: November 2021

Este trabajo edita la salida en prensa, en 1895, del cuento “La maga primavera”, hasta ahora no documentada, salvo en versión mecanoscrita de la autora, en el corpus pardobazaniano de cuentos dispersos. Tras una breve presentación de las circunstancias de su génesis, y de su posterior edición moderna a cargo de González Megía (2007), Patiño Eirín (2008) y González Herrán (2011), se glosan descriptivamente los rasgos discursivos y gráficos de su salida periodística en las páginas de La Crónica Meridional. Acompaña a la transcripción un aparato de notas que la coteja con el texto primigenio.
Speculative Performance Meets Immersive Learning: Lessons of Drylab2023
Authors: Jenik Adriene 
Published: November 2021

Drylab2023, an experiment in “immersive learning,” was conducted from May 13-June 11, 2017. Eight participants lived for 30 days in a remote desert outpost limited to 4 gallons of water per person per day to meet all water needs (drinking, cooking, washing, hygiene, etc) while subsisting on a water-wise diet. Participants were charged to live within a “near future scenario” of water scarcity (2023); modelling how to manage a limited vital resource: fresh water. During the experiment, narrative progress could be tracked as it unfolded through online posts at drylab2023.net.
This article argues that: 1) speculative performance is a powerful form of knowledge creation that can prefigure and manifest alternate ways of living with climate change; 2) the participants, scenario, environmental stage, and audience collaboratively produced the performance; 3) through performance – an embodied form of knowledge – the participants came to understand what it means to live water-wise; and 4) the use of the speculative (the narrative frame of 2023) allowed participants to reflect on the past and present as well as imagine the future.
Dynamic Spatial Tuning Patterns of Shoulder Muscles with Volunteers in a Driving Posture
Authors: Fice Jason B. , Larsson Emma , Davidsson Johan 
Published: November 2021

Computational human body models (HBMs) of drivers for pre-crash simulations need active shoulder muscle control, and volunteer data are lacking. The goal of this paper was to build shoulder muscle dynamic spatial tuning patterns, with a secondary focus to present shoulder kinematic evaluation data. 8M and 9F volunteers sat in a driver posture, with their torso restrained, and were exposed to upper arm dynamic perturbations in eight directions perpendicular to the humerus. A dropping 8-kg weight connected to the elbow through pulleys applied the loads; the exact timing and direction were unknown. Activity in 11 shoulder muscles was measured using surface electrodes, and upper arm kinematics were measured with three cameras. We found directionally specific muscle activity and presented dynamic spatial tuning patterns for each muscle separated by sex. The preferred directions, i.e. the vector mean of a spatial tuning pattern, were similar between males and females, with the largest difference of 31° in the pectoralis major muscle. Males and females had similar elbow displacements. The maxima of elbow displacements in the loading plane for males was 189 ± 36 mm during flexion loading, and for females, it was 196 ± 36 mm during adduction loading. The data presented here can be used to design shoulder muscle controllers for HBMs and evaluate the performance of shoulder models.
Computational Modelling and Big Data Analysis of Flow and Drug Transport in Microfluidic Systems: A Spheroid-on-a-Chip Study
Authors: Kheiri Sina , Kumacheva Eugenia , Young Edmond W.K. 
Published: November 2021

Microfluidic tumour spheroid-on-a-chip platforms enable control of spheroid size and their microenvironment and offer the capability of high-throughput drug screening, but drug supply to spheroids is a complex process that depends on a combination of mechanical, biochemical, and biophysical factors. To account for these coupled effects, many microfluidic device designs and operating conditions must be considered and optimized in a time- and labour-intensive trial-and-error process. Computational modelling facilitates a systematic exploration of a large design parameter space via in silico simulations, but the majority of in silico models apply only a small set of conditions or parametric levels. Novel approaches to computational modelling are needed to explore large parameter spaces and accelerate the optimization of spheroid-on-a-chip and other organ-on-a-chip designs. Here, we report an efficient computational approach for simulating fluid flow and transport of drugs in a high-throughput arrayed cancer spheroid-on-a-chip platform. Our strategy combines four key factors: i) governing physical equations; ii) parametric sweeping; iii) parallel computing; and iv) extensive dataset analysis, thereby enabling a complete “full-factorial” exploration of the design parameter space in combinatorial fashion. The simulations were conducted in a time-efficient manner without requiring massive computational time. As a case study, we simulated &gt;15,000 microfluidic device designs and flow conditions for a representative multicellular spheroids-on-a-chip arrayed device, thus acquiring a single dataset consisting of ∼10 billion datapoints in ∼95 GBs. To validate our computational model, we performed physical experiments in a representative spheroid-on-a-chip device that showed excellent agreement between experimental and simulated data. This study offers a computational strategy to accelerate the optimization of microfluidic device designs and provide insight on the flow and drug transport in spheroid-on-a-chip and other biomicrofluidic platforms.
ADAMTS9-AS1 Constrains Breast Cancer Cell Invasion and Proliferation via Sequestering miR-301b-3p
Authors: Chen Junqing , Cheng Ling , Zou Weibin , Wang Rong , Wang Xiaojia , Chen Zhanhong 
Published: November 2021

Objective: For determination of how ADAMTS9-AS1/miR-301b-3p/TGFBR2/JAK STAT signaling axis modulates progression of breast cancer cells.Methods: Target lncRNA was determined by differential analysis of breast cancer expression data and survival analysis. Differentially expressed miRNAs and target mRNAs that had binding sites with target lncRNA were predicted. GSEA software was used to carry out pathway enrichment analysis for mRNAs. Binding of the researched genes were tested with RNA binding protein immunoprecipitation (RIP). How miR-301b-3p bound TGFBR2 mRNA was tested by dual-luciferase method. Transwell, colony formation, EdU approaches were employed for verification of invasion and proliferation of breast cancer cells in each treatment group.Results: Markedly inactivated ADAMTS9-AS1 in breast cancer pertained to patient’s prognosis. MiR-301b-3p was capable of binding TGFBR2/ADAMTS9-AS1. However, overexpression of ADAMTS9-AS1 stimulated miR-301b-3p binding ADAMTS9-AS1 and repressed miR-301b-3p binding TGFBR2 mRNA. ADAMTS9-AS1 interference enhanced cancer proliferation and invasion, facilitated levels of KI67, PCNA, MMP-9 and MMP-2, and activated the JAK STAT signaling pathway. While silencing miR-301b-3p reversed the effect of ADAMTS9-AS1 interference. In addition, TGFBR2 interference or restraining JAK STAT signaling counteracted the effect of ADAMTS9-AS1.Conclusion: ADAMTS9-AS1 could sequester miR-301b-3p to inhibit progression of breast cancer via TGFBR2/JAK STAT pathway. This study supplies a rationale for incremental apprehension of ADAMTS9-AS1 in breast cancer progression.
Effects of Metoprolol on Periprocedural Myocardial Infarction After Percutaneous Coronary Intervention (Type 4a MI): An Inverse Probability of Treatment Weighting Analysis
Authors: Li Duanbin , Li Ya , Lin Maoning , Zhang Wenjuan , Fu Guosheng , Chen Zhaoyang , Jin Chongying , Zhang Wenbin 
Published: November 2021

Background: Metoprolol is the most used cardiac selective β-blocker and has been recommended as a mainstay drug in the management of acute myocardial infarction (AMI). However, the evidence supporting this regimen in periprocedural myocardial infarction (PMI) is limited.Methods: This study identified 860 individuals who suffered PMI following percutaneous coronary intervention (PCI) procedure and median followed up for 3.2 years. Subjects were dichotomized according to whether they received chronic oral sustained-release metoprolol succinate following PMI. After inverse probability of treatment weighting (IPTW) adjustment, logistic regression analysis, Kaplan-Meier curve, and Cox regression analysis were performed to estimate the effects of metoprolol on major adverse cardiovascular events (MACEs) which composed of cardiac death, myocardial infarction (MI), stroke, and revascularization. Moreover, an exploratory analysis was performed according to hypertension, cardiac troponin I (cTnI) elevation, and cardiac function. A double robust adjustment was used for sensitivity analysis.Results: Among enrolled PMI subjects, 456 (53%) patients received metoprolol treatment and 404 (47%) patients received observation. After IPTW adjustment, receiving metoprolol was found to reduce the subsequent 3-year risk of MACEs by nearly 7.1% [15 vs. 22.1%, absolute risk difference (ARD) = 0.07, number needed to treat (NNT) = 14, relative risk (RR) = 0.682]. In IPTW-adjusted Cox regression analyses, receiving metoprolol was related to a reduced risk of MACEs (hazard ratio [HR] = 0.588, 95%CI [0.385–0.898], P = 0.014) and revascularization (HR = 0.538, 95%CI [0.326–0.89], P = 0.016). Additionally, IPTW-adjusted logistic regression analysis showed that receiving metoprolol reduced the risk of MI at the third year (odds ratio [OR] = 0.972, 95% CI [0.948–997], P = 0.029). Exploratory analysis showed that the protective effect of metoprolol was more pronounced in subgroups of hypertension and cTnI elevation ≥1,000%, and was remained in patients without cardiac dysfunction. The benefits above were consistent when double robust adjustments were performed.Conclusion: In the real-world setting, receiving metoprolol treatment following PCI-related PMI has decreased the subsequent risk of MACEs, particularly the risk of recurrent MI and revascularization.
Incidence- and In-hospital Mortality-Related Risk Factors of Acute Kidney Injury Requiring Continuous Renal Replacement Therapy in Patients Undergoing Surgery for Acute Type a Aortic Dissection
Authors: Chen Xuelian , Zhou Jiaojiao , Fang Miao , Yang Jia , Wang Xin , Wang Siwen , Li Linji , Zhu Tao , Ji Ling , Yang Lichuan 
Published: November 2021

Background: Few studies on the risk factors for postoperative continuous renal replacement therapy (CRRT) in a homogeneous population of patients with acute type A aortic dissection (AAAD). This retrospective analysis aimed to investigate the risk factors for CRRT and in-hospital mortality in the patients undergoing AAAD surgery and to discuss the perioperative comorbidities and short-term outcomes.Methods: The study collected electronic medical records and laboratory data from 432 patients undergoing surgery for AAAD between March 2009 and June 2021. All the patients were divided into CRRT and non-CRRT groups; those in the CRRT group were divided into the survivor and non-survivor groups. The univariable and multivariable analyses were used to identify the independent risk factors for CRRT and in-hospital mortality.Results: The proportion of requiring CRRT and in-hospital mortality in the patients with CRRT was 14.6 and 46.0%, respectively. Baseline serum creatinine (SCr) [odds ratio (OR), 1.006], cystatin C (OR, 1.438), lung infection (OR, 2.292), second thoracotomy (OR, 5.185), diabetes mellitus (OR, 6.868), AKI stage 2–3 (OR, 22.901) were the independent risk factors for receiving CRRT. In-hospital mortality in the CRRT group (46%) was 4.6 times higher than in the non-CRRT group (10%). In the non-survivor (n = 29) and survivor (n = 34) groups, New York Heart Association (NYHA) class III-IV (OR, 10.272, P = 0.019), lactic acidosis (OR, 10.224, P = 0.019) were the independent risk factors for in-hospital mortality in patients receiving CRRT.Conclusion: There was a high rate of CRRT requirement and high in-hospital mortality after AAAD surgery. The risk factors for CRRT and in-hospital mortality in the patients undergoing AAAD surgery were determined to help identify the high-risk patients and make appropriate clinical decisions. Further randomized controlled studies are urgently needed to establish the risk factors for CRRT and in-hospital mortality.