bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID‐19‐related thyroiditis: A novel disease entity?
Authors: Dworakowska Dorota , Morley Simon , Mulholland Nicola , Grossman Ashley B 
Published: March 2021

AbstractThe literature on COVID‐19‐related thyroid complications has accumulated over the past year or so as the pandemic has accelerated throughout the world. In particular, several recent case reports have been published describing a possible correlation between COVID‐19 disease and subacute thyroiditis (SAT). In this review, we briefly present one of our own patients and review the current published literature in this area up to January 2021, including analyses of major series of thyroid function tests in patients with significant COVID‐19 infection. We conclude that while the great majority of patients with severe COVID‐19 infection may show manifestations of the sick euthyroid syndrome, clinicians should be aware of the possibility of SAT, especially in the early weeks and months following even mild COVID‐19 infection.
MiR‐467b alleviates lipopolysaccharide‐induced inflammation through targeting STAT1 in chondrogenic ATDC5 cells
Authors: Jin Feng , Liao Leming , Zhu Yongjun 
Published: March 2021

AbstractOsteoarthritis (OA) is one of the most common degenerative joint diseases worldwide. Chondrocytes are activated in OA patients, accompanied by excessive chondrogenic proliferation and production of inflammatory cytokines. MiR‐467b is implicated in the regulation of artherosclerosis and pro‐inflammatory cytokine secretion. However, the precise role of miR‐467b in OA remains unclear. In the present study, we induced inflammation in chondrogenic ATDC5 cells using lipopolysaccharide (LPS). LPS treatment significantly elevated the production of interleukin‐6 (IL‐6), IL‐1β and tumour necrosis factor‐α (TNF‐α) in ATDC5 cells, accompanied by decreased miR‐467 level. Then, we over‐expressed miR‐467b using its specific mimics in ATDC5 cells, and LPS‐induced inflammation was significantly inhibited as evidenced by decreased IL‐6, IL‐1β and TNF‐α levels. MiR‐467b agomir also alleviated inflammation in rat knee osteoarthritis (KOA) model. In addition, we validated that signal transducer and activator of transcription 1 (STAT1) was a downstream target of miR‐467b. LPS treatment significantly increased the STAT1 expression while miR‐467b mimic transfection partially reversed this effect. Moreover, STAT1 knockout reversed the increased contents of IL‐6, IL‐1β and TNF‐α. Furthermore, miR‐467b over‐expression significantly decreased the production of IL‐6, IL‐1β and TNF‐α induced by LPS treatment, which was partially reversed by further STAT1 over‐expression. In summary, our findings demonstrated that miR‐467b alleviated LPS‐induced inflammation through targeting STAT1, and this miR‐467b/STAT1 regulation axis may provide a new therapeutic target for OA clinical management.
Pregnancy Options Counseling and Abortion Referral Practices Among Colorado Nurse Practitioners, Nurse‐Midwives, and Physician Assistants
Authors: Coleman‐Minahan Kate 
Published: March 2021

IntroductionAccess to abortion is a public health priority. Yet little is known about pregnancy options counseling and abortion referral practices, both essential to timely abortion care, among advanced practice clinicians (APCs; nurse practitioners, nurse‐midwives, physician assistants).MethodsData were drawn from a stratified random sample of Colorado APCs, oversampling certified nurse‐midwives (CNMs), women's health nurse practitioners (WHNPs), and rural clinicians. Pregnancy options counseling and abortion referral practices were described. Weighted multivariate logistic regression models were used to examine associations between participant characteristics and providing options counseling, referring for abortion, and referring to crisis pregnancy centers.ResultsOf 513 participants (response rate 21%), 419 provided pregnancy testing. Only 201(48%) reported they were willing and able to counsel on all 3 options. Religious or personal objection was the primary rationale for unwillingness to present abortion as an option (63%). However, lack of knowledge was the main rationale for unwillingness (64%) and inability to counsel (79%), whereas institutional barriers fueled inability to refer (59%). Although 53% referred for abortion care, 31% referred to crisis pregnancy centers. Characteristics positively associated with providing options counseling included being a CNM or WHNP (odds ratio [OR], 2.73; 95% CI, 1.32‐5.66), having received options counseling training (OR, 2.84; 95% CI, 1.48‐5.43), and feeling adequately trained on abortion counseling (OR, 6.61; 95% CI, 3.62‐12.08). Characteristics positively associated with referring for abortion included being a CNM or WHNP (OR, 2.27; 95% CI, 1.18‐4.36), having received options counseling training (OR, 2.39; 95% CI, 1.36‐4.22), and feeling adequately trained on abortion counseling (OR, 3.5; 95% CI, 2.00‐6.11). Only provider type was associated with referring to crisis pregnancy centers; CNMs and WHNPs had the lowest odds (OR, 0.29; 95% CI, 0.15‐0.54).DiscussionPregnant patients in Colorado may not receive evidence‐based pregnancy options counseling or abortion referrals. Clinician training on options counseling and abortion referrals is needed.
Desiccation and temperature resistance of the larger grain borer, Prostephanus truncatus (Horn) (Coleoptera: Bostrichidae): pedestals for invasion success?
Authors: Mutamiswa Reyard , Machekano Honest , Singano Charles , Joseph Virgil , Chidawanyika Frank , Nyamukondiwa Casper 
Published: March 2021

AbstractThe larger grain borer, Prostephanus truncatus (Horn) is an invasive insect pest species of global economic concern. It however remains unknown how P. truncatus succeeds under increasing temperatures and desiccation effects associated with projected climate change. Here, we investigated the effects of desiccation and high‐temperature stress on physiological fitness of P. truncatus larvae and adults. Specifically, we measured critical thermal maxima, heat knockdown time and water loss rates following heat and desiccation acclimation. Results showed beneficial heat acclimation effects on heat tolerance (critical thermal maxima and heat knockdown time). Similarly, desiccation acclimation significantly improved both heat tolerance traits, indicating cross‐tolerance effects, not for heat knockdown time in larvae. In all cases, adults exhibited more improved heat tolerance than larvae. Conversely, heat acclimation increased water loss rates, and more so in larvae than adults. Improved heat tolerance plus abiotic stress cross‐tolerance of P. truncatus may explain its enhanced physiological and ecological fitness in dry tropical and changing climate environments. These results are important in explaining the role of physiology in insect invasions and may inform pest management and forecasting.
A preliminary study to understand the effects of mask on tinted face cosmetics
Authors: Yokoyama Emilie , Udodaira Kumiko , Nicolas Alexandre , Yamashita Eri , Maudet Aurelie , Flament Frederic , Velleman Damien 
Published: March 2021

AbstractBackgroundThe recent COVID‐19 pandemic has generalized the use of face mask in public area, and it is now common to wear it for long hours. But face mask interfere with cosmetics, and key concerns for tinted products are staining of the mask and degradation on face. Consumers have modified beauty routine by a decrease of makeup, but are now expecting new products adapted to face mask. Little is known about the mechanisms that affect most the makeup under the face mask, so that further studies are needed to develop adequate evaluation methods and products. In this study, the color transfer on mask and makeup degradation on face are assessed through a mixed approach of consumer and instrumental evaluation.Materials and MethodsTwo tinted face products (A and B) were applied by half face on 11 Japanese women, who conducted real‐life activities with a face mask during 4 hours. Panelists evaluated the stain of their face mask by visual assessment, while the makeup degradation on face was evaluated by color measurement by instrumental method.ResultsNo difference was observed between the two products for lasting on face, but consumer evaluation showed a better resistance of product A for color transfer on mask.ConclusionThe mix of instrumental and consumer evaluation is a promising way to evaluate the makeup degradation on face and color transfer on mask, which are two key factors to develop mask resistant makeup products.
Experiences and perceptions of family members of emergency first responders with post-traumatic stress disorder: a qualitative systematic review protocol
Authors: May Karen , Van Hooff Miranda , Doherty Matthew , Iannos Marie 
Published: March 2021

ABSTRACT

Objective:
The objective of this review is to understand the perceptions and experiences of family members of emergency first responders with post-traumatic stress disorder.

Introduction:
Research indicates that rates of post-traumatic stress disorder in emergency first responders are approximately double civilian rates; however, little is known about the effects of post-traumatic stress disorder on family members. This review seeks to identify qualitative research on families’ experiences and perceptions.

Inclusion criteria:
This review will consider all studies of family members of current or former emergency first responders with diagnosed or undiagnosed post-traumatic stress disorder of any level of severity. All possible familial configurations and family members will be considered, including nuclear, separated, and blended families, of a current or former emergency first responder. There will be no age restrictions on emergency first responders or their family members, or limitations on recency of service. Emergency first responders may include police, ambulance workers, paramedics, firefighters, or rescue personnel, with no restriction on geographic location.

Methods:
The databases to be searched will include PubMed, PsycINFO, Embase, CINAHL, PTSDpubs, and Scopus, as well as handsearching of relevant journals. Unpublished studies and gray literature will be searched via PTSDpubs and OpenGrey. The search will aim to find English-language publications with no time limits. Titles and abstracts will be reviewed and then full texts, all screened by two independent reviewers against the inclusion criteria. Any conflicting views will be resolved by discussion or a third reviewer. Results will be critically appraised for methodological quality. Data extraction results will be synthesized and evaluated for credibility and dependability.

Systematic review registration number:
PROSPERO CRD42020196605
Physiotherapists’ and physiotherapy students’ attitudes and beliefs about working with people with dementia: a mixed methods systematic review protocol
Authors: Quick Stephen M. , Snowdon David A. , Lawler Katherine , McGinley Jennifer L. , Soh Sze-Ee , Callisaya Michele L. 
Published: March 2021

ABSTRACT

Objective:
The objective of this review is to explore the attitudes and beliefs of physiotherapists and physiotherapy students working with people with dementia. A second objective is to explore their knowledge and confidence in this area.

Introduction:
Dementia is a leading cause of disability. It poses a challenge to individuals and health systems due to the complex nature of its presentation. With a growing body of evidence supporting physiotherapists’ role in the care of people with dementia, it is important to understand their knowledge, confidence, attitudes, and beliefs in managing this role.

Inclusion criteria:
The review will consider quantitative, qualitative, and mixed-methods studies that include physiotherapists and physiotherapy students who have worked or had a clinical placement in any setting where people with dementia might access physiotherapy care. Studies investigating one or more of the following topics will be included: knowledge, confidence, attitudes, and beliefs about working with people with any type of dementia.

Methods:
MEDLINE (Ovid), CINAHL (EBSCO), Embase (Ovid), Emcare, PsycINFO (Ovid), Scopus, Web of Science, Informit, ERIC (ProQuest), ProQuest Dissertations, and Google Scholar will be searched without a date limit for studies published in English. All study types will be screened for inclusion and critically appraised for methodological quality by two independent reviewers. Methodological quality will be assessed using the appropriate JBI critical appraisal checklist for each study type. Data will be extracted using standardized JBI tools for mixed methods systematic reviews. A convergent integrated approach to synthesis and integration will be used.

Systematic review registration number:
PROSPERO CRD42020181845
Use of mHealth apps by nurses in the management of chronic wounds: a scoping review protocol
Authors: Vaughan Grainne , Prizeman Geraldine , Eustace-Cook Jessica , Byrne Gobnait 
Published: March 2021

ABSTRACT

Objective:
The objective of this scoping review is to explore the existing literature related to nurses’ use of mHealth apps in the management of chronic wounds and chart if and how these apps are being evaluated.

Introduction:
mHealth technology is increasingly used within health care facilities. There is now a variety of wound care apps available to support nurses delivering wound care. These promise many benefits, but little is known about their use.

Inclusion criteria:
Studies involving nurses of all grades, in all clinical settings using mHealth apps in the care and management of chronic wounds will be included. Criteria used to evaluate these apps will also be considered. The context will be all primary care, hospital, and community settings, which includes general practice, nurse-led clinics, public health services, nursing and care homes, and all hospital settings. There will be no limit on the geographical setting of the research. All studies and reports that focus on qualitative, quantitative, and mixed methods will be included, as will text and opinion papers and published gray literature.

Methods:
An initial search of MEDLINE, CINAHL, and Embase will be undertaken to identify index terms. This will be followed by an analysis of the text words contained in the title. A search of commercial app stores (eg, Apple's App Store and Google's Play Store) will not be carried out. A data extraction form will be used and piloted on the first 10 articles. Results will be reported in tabular form and presented in a PRISMA flow diagram.
Lubrication and Fluid Film Study on the Vane Tip in a Vane Pump Hydraulic Transmission Considering a Fluid and Structure Interaction
Authors: Wang Feng , Sun Zhenxing , Fiebig Wieslaw , Xu Bing , Stelson Kim A. 
Published: March 2021

Abstract
A mathematical modeling approach to determine fluid film thickness on the vane tip in a vane pump transmission is developed. The transmission is based on a double-acting vane pump with an additional output shaft coupled to a floating ring. Owing to the floating ring design, the internal viscous friction helps to drive the output shaft, whereas the friction is turned into heat in a conventional vane pump. To study the mechanical efficiency, it is crucial to investigate the fluid film thickness between the vane tip and the ring inner surface. The modeling approach in this study takes the interactions between vane radial motion and chamber pressure dynamics into consideration, without using a computational fluid dynamics approach. The lubrication on the vane tip is considered as elasto-hydrodynamic lubrication and the fluid film thickness calculation is based on the Hooke lubrication diagram. Results show that the developed simulation model is capable of revealing the fluid film thickness change and vane radial motion in different operation regions. Sensitivity studies of several parameters on the minimum fluid film thickness are also presented.
The Effect of Heating Duration on the Quantitative Estimation of Defect Depth Using Sonic Infrared Imaging
Authors: Obeidat Omar , Yu Qiuye , Favro Lawrence , Han Xiaoyan 
Published: March 2021

Abstract
Sonic infrared (SIR) imaging is an original hybrid nondestructive evaluation (NDE) technique that has seen rapid acceptance in the industry. A single-tone ultrasonic wave in the 15–40 kHz range is induced to the specimen under inspection through a high-power ultrasonic plastic welder. Heating duration is equal to the ultrasonic excitation duration. In a previous article, an analytical model for depth profiling using SIR NDE was presented. According to the proposed model, material thermal properties, defect size and ultrasonic excitation duration influence defect characterization and contribute to the total temperature-time curves. In this paper, heating duration effect on the quantitative estimation of flaws using sonic infrared nondestructive evaluation was investigated.
Adaptation to Athletic Retirement and Perceptions About Aging: A Qualitative Study of Retired Olympic Athletes
Authors: Silver Michelle Pannor 
Published: March 2021

Self-perceptions about aging have implications for health and well-being; however, less is known about how these perceptions influence adaptation to major life transitions. The goal of this study was to examine how high-performance athletes’ perceptions about aging influenced their adaptation to athletic retirement. In-depth interviews conducted with 24 retired Olympic athletes using thematic analysis yielded three key themes: (a) perceptions about aging influenced participants’ postretirement exercise habits, (b) perceptions about aging motivated participants to engage in civic activities, and (c) participants who lacked formative perceptions about aging associated their athletic retirement with their own lost sense of purpose. These findings provide evidence that perceptions about aging influence athletes’ adaptation to retirement by directing their subsequent engagement in postretirement activities. Furthermore, this research highlights theoretical implications for the literature regarding embodied processes, retirement transitions, role models, and adaptation to new physical states.
Temporal effect of acupuncture on amino acid neurotransmitters in rats with acute cerebral ischaemia
Authors: Liu Jing , Wu Yuan-Yuan , Yu Xiao-lei , Jia Hong-Yang , Mao Qun-Yan , Fang Jian-Qiao 
Published: March 2021

Background: Acupuncture stimulation at GV26 during the acute phase of cerebral ischaemia can effectively reduce brain damage induced by ischaemic injury. However, the time course of the effects of acupuncture stimulation has not yet been thoroughly studied. Objective: To investigate the effects of manual acupuncture (MA) on glutamic acid (Glu) and γ-aminobutyric acid (GABA) expression in the cerebrospinal fluid of rats with middle cerebral artery occlusion (MCAO) and determine whether there is a temporal effect of acupuncture on the treatment of cerebral ischaemia. Methods: We performed thread occlusion of the right middle cerebral artery in rats to establish an animal model of MCAO. Simultaneously, during acupuncture treatment, microdialysis was used to continuously and dynamically observe immediate alterations in amino acid metabolism with acupuncture stimulation after cerebral ischaemia in vivo in this rat model of MCAO. Results: We found that, in comparison with an untreated MCAO group, Glu content was significantly decreased during the first acupuncture stimulation and during the course of the acupuncture treatment in the MCAO+MA group (MCAO vs MCAO+MA: day 1, P=0.032; day 2, P=0.021; day 3, P=0.017). These findings were also seen after the end of treatment when acupuncture was no longer applied (MCAO vs MCAO+MA: day 7, P=0.009). Measurements of GABA content following cerebral ischaemic injury showed that GABA peaks 24 hours after damage, falls thereafter and decreases to baseline levels on day 7. In the MCAO+MA group, GABA content on days 1 to day 2 was lower than in the MCAO group (MCAO+MA vs MCAO: day 1, P=0.003; day 2, P=0.001), although it was higher than in the control group (MCAO+MA vs control: day 1, P=0.024; day 2, P=0.009). GABA content on day 3 and day 7 was higher in the MCAO+MA group than in the MCAO group and the control group (MCAO+MA vs MCAO: day 3, P=0.008; day 7, P=0.013; MCAO+MA vs control: day 3, P=0.002; day 7, P=0.009). Conclusion: Acupuncture stimulation at GV26 can effectively decrease excessive release of Glu induced by ischaemia and maintain the endogenous inhibitory activity of GABA. This phenomenon was seen during the entire course of acupuncture treatment and continued for some time after the end of acupuncture treatment.
Effect of moxibustion on the expression of GDNF and its receptor GFRα3 in the colon and spinal cord of rats with irritable bowel syndrome
Authors: Qi Qin , Wu Huangan , Jin Xiaoming , Jin Duiyin , Wang Yuanyuan , wang Cun , Liu Yanan , Wang Xiaomei 
Published: March 2021

Background: Moxibustion treatment has been found to ameliorate clinical symptoms including abdominal pain, diarrhoea and constipation in patients with irritable bowel syndrome (IBS). Herein we investigated the mechanisms underlying the use of moxibustion in a rat model of IBS. Methods: In our study, an IBS model was established in rats by colorectal distension (CRD) stimulus and mustard oil enema. The rats were randomly divided into a normal group, model group, mild moxibustion group, electroacupuncture group, probiotic group and dicetel group. Abdominal withdrawal reflex (AWR) scores were determined within 90 min of the last treatment. The expression of GDNF/GFRα3 protein and mRNA in the colon and spinal cord were detected by immunohistochemistry and quantitative real-time-PCR, respectively. Results: The IBS model rats had significantly higher AWR scores than the normal group ( P<0.01). After mild moxibustion treatment, the AWR score was significantly reduced (20 mm Hg, P<0.05; 40 mm Hg, 60 mm Hg and 80 mm Hg, P<0.01). The model group showed significantly more colonic glial cell line-derived neurotrophic factor (GDNF/GFRα3 (GDNF family receptor α3) protein and mRNA expression in the colon and spinal cord than the normal group ( P<0.01). Compared with the model group, the expression of GDNF/GFRα3 protein and mRNA in the colon and spinal cord of the rats were significantly decreased in the mild moxibustion group (colon: GDNF and GFRα3 protein, P<0.01; GDNF and GFRα3 mRNA, P<0.01; spinal cord: GDNF and GFRα3 protein, P<0.01; GDNF mRNA, P<0.05, GFRα3 mRNA, P<0.01). Conclusions: Our data suggest that moxibustion therapy may mitigate CRD-induced increases in the expression of GDNF and its receptor GFRα3 in the colon and spinal cord in a rat model of IBS.