bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamic capabilities for the creation of logistics flexibility – a conceptual framework
Authors: Sandberg Erik 
Published: January 2021

PurposeThe purpose of this research is to develop a conceptual framework in which dynamic capabilities (DCs) for the creation of logistics flexibility are outlined, and elaborate it further based on empirical data from a case study at a Swedish fast fashion retailer.Design/methodology/approachA conceptual framework that aims to delineate the relationship between generic classes of DCs and logistics flexibility is proposed. Thereafter, based on a theory elaboration approach, empirical data from a case study at a Swedish fast fashion retailer is used to identify more specific DCs and further outline the characteristics of the DCs classes.FindingsThe proposed framework draws on the three DC classes of sensing, seizing and reconfiguring, and how they underscore logistics range and logistics response flexibility. The framework also distinguishes between DC classes and logistics flexibility that occur at operational, structural and strategic levels. DCs for the creation of logistics flexibility at a Swedish fast fashion retailer have also been identified and described as a means to further elaborate the characteristics of the DC classes.Research limitations/implicationsCurrent empirical data is limited to one specific company context.Practical implicationsThe research presents a systematic and comprehensive map of different DCs that underscore logistics flexibility, a useful tool supporting logistics development efforts regarding flexibility.Originality/valueThe establishment of a more detailed DC lens, in which different classes of DCs are included, means that an improved understanding for how flexibility is created can be achieved. It helps the research to move beyond the “here and now” existence of logistics flexibility to instead focus on how logistics flexibility can be created.
Correlates of intimate partner violence in Bhutan: Evidence from the 2012 National Health Survey
Authors: Phuntsho Sonam , Dendup Tashi , Putra I Gusti Ngurah Edi , Gurung Mongal Singh , Pelzom Dorji , Wangmo Neyzang 
Published: January 2021

PurposeThis paper is to examine the factors associated with partner violence (IPV) in Bhutan.Design/methodology/approachThe nationally representative National Health Survey data conducted in 2012 was used. The survey included 12,210 women aged 15–75 years. Multiple logistic regression accounting for complex survey design was performed to assess the possible association of the putative factors with physical, sexual, psychological and any IPV experienced in the past 12 months before the survey.FindingsAlcohol consumption, quarrelling habits and extramarital relationships of husbands/partners were associated with the experience of all types and any IPV. Women performing household chores had increased odds of sexual and any IPV, and those whose husbands had low education levels were more likely to experience physical IPV. Women living in households with >9 members had reduced odds of physical and any IPV. Women married to older husbands/partners were less likely to be psychologically abused. Women from poorer wealth quintiles and who married before reaching 18 years of age also had greater odds of any IPV.Originality/valuePoor relationship quality, alcohol use, household size, low education, early marriage, poor wealth status and husband’s age were factors associated with one or more types of IPV in Bhutan. Interventions to reduce alcohol use, transform social norms, promote healthy relationships and enhance female empowerment through socio-economic programs may help prevent IPV.
Dietary habits in Japanese patients with palmoplantar pustulosis
Authors: Serizawa Naotaka , Okazaki Shizuka , Otsuka Yohei , Koto Mototaka , Okabe Kyochika , Ito Michiko , Morita Takashi , Hoashi Toshihiko , Saeki Hidehisa , Abe Namiko , Mori Miho , Okubo Yukari , Yano Yumiko , Mitsui Hiroshi , Kanda Naoko 
Published: January 2021

AbstractPalmoplantar pustulosis (PPP) is a chronic dermatitis characterized by sterile intra‐epidermal pustules associated with erythema and scales on the palms and soles. Tumor necrosis factor (TNF)‐α/interleukin (IL)‐23/IL‐17 inflammatory pathway may be involved in the pathogenesis of PPP, and the skin lesions manifest the enhanced expression of IL‐8 in keratinocytes and increased levels of antimicrobial peptide cathelicidin, leucine leucine‐37 in vesicles/pustules. Some PPP patients are associated with arthro‐osteitis, called pustulotic arthro‐osteitis (PAO). Dietary habits may modulate the pathogenesis of PPP, however, have not been investigated in PPP patients. We evaluated dietary habits in adult Japanese PPP patients, using a validated, brief‐type self‐administered diet history questionnaire, and compared their results to those of age‐ and sex‐matched healthy controls. The results in PPP patients with PAO were compared to those in the patients without. Japanese PPP patients showed higher body mass indices (BMIs), higher intakes of pulses and sugar/sweeteners, and lower intake of vitamin A, compared to those of healthy controls. The bivariate and multivariable logistic regression analysis showed that PPP was associated with high BMI, high intake of pulses, and low intake of vitamin A. The sodium intake and BMI were positively correlated with palmoplantar pustulosis area and severity index (PPPASI). The linear multivariate regression analysis revealed that sodium intake and BMI were predictors of PPPASI. The age and sodium intake in the patients with PAO were lower than those in the patients without. The bivariate and multivariable logistic regression analysis showed that PAO was negatively associated with age and sodium intake. This is the first study showing the dietary habits in patients with PPP. Further studies should clarify if the dietary intervention to correct the BMI and sodium intake will alter the progress of PPP.
Widening the Screen: Playful Responses to Challenges in Online Therapy with Children and Families
Authors: Vermeire Sabine , Van den Berge Luc 
Published: January 2021

The growing demand for online work with children, youngsters and their families during the Covid19 pandemic presented new challenges. The well‐trodden roads had to be left. In this article we explore novel online ideas in systemic and narrative therapy. Playfulness in online work invites curiosity, vividness and collaboration, and vice versa. We conceive of it as an antidote for pitfalls and as an inspiration for responses to the threat of reductionism that lurks around the corner, especially in online work. It offers a stepping stone to a serious exploration and sharing of experiences, stories and meanings that help to develop richer understandings and more creative ideas. It is a source of new ways of relating for family members as well as for the therapist and the family. Finally, playfulness enables the weaving of threads and experiencing a sense of continuity between sessions. We illustrate our quest using several case stories.Practitioner pointsPlayfulness as an atmosphere, attitude and intervention in online work invites curiosity, vividness and collaboration (and vice versa) while opening new therapeutic possibilities.Keeping a broad systemic scope and inviting members of the actual and imaginary network works as an antidote to the threat of reductionism in online therapy.A playful use of the online medium creates new relational dances between family members as well as between the therapist and the family.
Peritoneal sodium removal compared to glucose absorption in peritoneal dialysis patients treated by continuous ambulatory peritoneal dialysis and automated peritoneal dialysis with and without a daytime exchange
Authors: Tangwonglert Theerasak , Davenport Andrew 
Published: January 2021

AbstractSodium removal in peritoneal dialysis (PD) depends on convective clearance, typically generated by a glucose gradient, but this can result in glucose absorption. We wished to determine which factors determine peritoneal sodium losses to glucose absorption (PD Na/Gluc). Peritoneal sodium losses and glucose absorption were calculated from measured 24‐h collections of PD effluent, in patients attending for assessment of peritoneal membrane function. Five hundred and fifty eight patients; 317 (56.8%) males, mean age 56.1 ± 16.0 years, were studied, 281 treated by automated peritoneal dialysis (APD) with a daytime exchange (50.4%); 179 (32.1%) by APD and 98 (17.6%) by continuous ambulatory peritoneal dialysis (CAPD). All patients used glucose containing dialysates, with 352 (63.1%) using icodextrin and 210 (37.6%) hypertonic (22.7 g/L glucose) dialysates. The ratio of PD Na/Gluc was 0.14 (0.02–0.29). Patients using icodextrin had a higher ratio (0.16 (0.03–0.32) versus 0.11 (−0.02–0.26), P < .001), as did those using 22.7 g/L glucose versus 13.6 g/L (0.16 (0.06–0.32) versus 0.13 (−0.01–0.19), P < .01), and CAPD versus APD (0.18 (0.05–0.36) versus 0.11 (0.0–0.27), P < .05), respectively. A multivariable model showed that 24‐h ultrafiltration (odds ratio [OR] 7.6 (95% confidence interval [3.9–14.8]), P < .001 was associated with increased PD Na/Gluc, whereas APD (OR 0.19 (0.06–0.62), P < .01 and increased extracellular water to total body water (OR 0.001 [0–0.08], P = .03) were associated with lower ratios. Twenty four‐hour peritoneal ultrafiltration was strongly associated with PD Na/Gluc, whereas patients treated with APD cyclers without a daytime icodextrin exchange and those with an increased extracellular water to total body water had lower peritoneal sodium losses but with greater peritoneal glucose absorption.
Artificial diet development for mass rearing and its effect on the reproduction of yellow peach moth, Conogethes punctiferalis (Guenée)
Authors: Jing Dapeng , Zhang Tiantao , Bai Shuxiong , He Kanglai , Prabu Sivaprasath , Wang Zhenying 
Published: January 2021

AbstractYellow peach moth, Conogethes punctiferalis (Guenée) (Lepidoptera: Crambidae), is a very destructive fruit borer in Eastern Asia and Australia. A successful artificial diet and rearing protocol are urgently needed for its biological control and research. In this study, we developed and assessed four artificial diets: AD‐1, AD‐2, AD‐3 and AD‐4, for rearing yellow peach moth larvae. AD‐1 is effective supplements, leading to the larval survival rate of 82.05%, percentage of pupation 79.48%, mean pupa weight of 76.53 mg, emergence rate of 95.25%, and an adult fecundity rate of 121 eggs/female. Using it to feed can shorten the whole generation developmental period to 33 days. Based on this diet AD‐1, we also develop a suitable mass rearing method. During the larval stages providing three‐ to four‐time fresh diet can keep a healthy larval colony.
Tracing dual entry beyond the Eurocentric boundary
Authors: Wang Jenny Jing , Cortese Corinne 
Published: January 2021

AbstractThis paper aims to trace the origins of dual entry beyond a Eurocentric boundary. The aim can be refined further by asking: did the Chinese use dual entry and how did dual entry appear in Europe. Double entry is more advanced as it includes the location of the account in which the contra entry is made. Dual entry approaches accounting, like mathematics, as a tautology, whereby an equation is constructed from a simple axiom. Defined as such, this paper argues that the concept of dual entry had its earliest origins in China.
An exploratory study of perfectionism, professional factors and psychological well‐being of dentistry academics
Authors: Teixeira H , Lalloo R , Evans JL , Fuss J , Pachana NA , Nović A , Burton NW 
Published: January 2021

AbstractBackgroundWell‐being might be lower among dentistry professionals than other health professionals, and differ by personal, professional and sociodemographic factors. Few studies have considered dentistry academics who have different work roles and functions than clinicians. This exploratory study focused on well‐being among dentistry academics and aimed to explore associations with perfectionism, professional factors and sociodemographics.MethodAn online survey was carried out with academic staff in Dentistry and Oral Health departments of nine Universities in Australia and New Zealand. Well‐being was assessed using the 22‐item Psychological General Well‐Being Index, with a maximum score of 110 indicating good well‐being. Perfectionism was assessed using the 8‐item Short Almost Perfect Scale, with a maximum score of 56 and a higher score indicating perfectionism. Twenty items were used to assess professional and 7 items assessed sociodemographic factors. Associations were explored using correlation and multiple linear regression.ResultsThere was no significant bivariate association between perfectionism and well‐being. Multiple linear regression indicated a significant association between hours of undergraduate teaching and psychological well‐being, after adjustment for age, gender, income and overall health.ConclusionThis exploratory study showed poor well‐being among dentistry academics, particularly in those teaching undergraduate students for more than 6 h/week.
Psychometric properties of the assessment of COVID‐19 attitudes and behaviors
Authors: Silverstein Madison W. , Mekawi Yara , Alonzi Sarah P. , La Torre Adelaide 
Published: January 2021

AbstractDeveloping psychometrically validated assessment tools to examine social and intergroup processes related to COVID‐19 is fundamental for creating interventions that reduce the spread of this virus. Thus, this manuscript aimed to evaluate the psychometric properties of a new measure, Assessment of COVID‐19 Attitudes and Behaviors (ACAB), that assesses COVID‐19‐related attitudes (e.g., about physical distancing, xenophobia), behaviors (e.g., helping others versus prioritizing own needs), and beliefs (e.g., about others’ roles in spreading COVID‐19). We used exploratory and confirmatory factor analyses (EFA, CFA) to provide factor analytic support and Fisher's r‐to‐z transformation to provide construct validity evidence. EFA revealed and CFA confirmed a four‐factor structure of social distancing adjustment, self‐prioritization, prosocial behaviors, and belief in conspiracies. Fisher's r‐to‐z transformation provided evidence for the construct validity of the four factors. This psychometrically validated instrument will enhance social science researchers’ ability to accurately identify and explicate psychological processes related to COVID‐19.
Gene expression in the striatum of cynomolgus monkeys after chronic administration of cocaine and heroin
Authors: Choi Mi Ran , Jin Yeung‐Bae , Kim Han‐Na , Chai Young Gyu , Im Chang‐Nim , Lee Sang‐Rae , Kim Dai‐Jin 
Published: January 2021

AbstractCocaine and heroin cause impairment of neural plasticity in the brain including striatum. This study aimed to identify genes differentially expressed in the striatum of cynomolgus monkeys in response to cocaine and heroin. After chronic administration of cocaine and heroin in the monkeys, we performed large‐scale transcriptome profiling in the striatum using RNA‐Seq technology and analysed functional annotation. We found that 547 and 1238 transcripts were more than 1.5‐fold up‐ or down‐regulated in cocaine‐ and heroin‐treated groups, respectively, compared to the control group, and 3432 transcripts exhibited differential expression between cocaine‐ and heroin‐treated groups. Functional annotation analysis indicated that genes associated with nervous system development (NAGLU, MOBP and TTL7) and stress granule disassembly (KIF5B and KLC1) were differentially expressed in the cocaine‐treated group compared to the control group, whereas gene associated with neuron apoptotic process (ERBB3) was differentially expressed in the heroin‐treated group. In addition, IPA network analysis indicated that genes (TRAF6 and TRAF3IP2) associated with inflammation were increased by the chronic administration of cocaine and heroin. These results provide insight into the correlated molecular mechanisms as well as the upregulation and down‐regulation of genes in the striatum after chronic exposure to cocaine and heroin.
Feasible interventions for children in foster care according to service users and practitioners
Authors: Sørensen Kresta Munkholt , Sjoe Nina Madsen 
Published: January 2021

AbstractMultiple obstacles exist to introducing evidence‐based methods in social work practice. The study directly interacts with social work practice and maps the interventions practice prioritizes when supporting children or parents. Specifically, the study examines service users' and practitioners' assessment of the feasibility of systematically evaluated interventions in the everyday life of foster care families. To integrate the different perspectives, we use a three‐step process comprising a systematic review of interventions for children in foster care, a literature review of challenges faced by the children to assist with choosing the most relevant interventions and a discussion of findings with service users and practitioners. The systematic review identified 51 interventions. The literature review revealed three common challenges: collaboration with the birth family, behavioural issues and social problem solving. We reduced the 51 interventions to 13 for discussions in workshops and interviews with service users and practitioners and ended up with two feasible interventions: incredible years and collaboration meetings. The first has been evaluated in several randomized studies, whereas the second has been evaluated qualitatively. Our analysis points to a profession where systematic and evidence‐based knowledge is subordinated to a pragmatism that prioritizes budgeting and prior knowledge of interventions.
Hybrid physiologically‐based pharmacokinetic model for remdesivir: Application to SARS‐CoV‐2
Authors: Gallo James M. 
Published: January 2021

AbstractA novel coronavirus, severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) or coronavirus disease 2019 (COVID‐19), has caused a pandemic that continues to cause catastrophic health and economic carnage and has escalated the identification and development of antiviral agents. Remdesivir (RDV), a prodrug and requires intracellular conversions to the active triphosphate nucleoside (TN) has surfaced as an active anti‐SARS‐CoV‐2 drug. To properly design therapeutic treatment regimens, it is imperative to determine if adequate intracellular TN concentrations are achieved in target tissues, such as the lungs. Because measurement of such concentrations is unrealistic in patients, a physiologically‐based pharmacokinetic (PBPK) model was developed to characterize RDV and TN disposition. Specifically, a hybrid PBPK model was developed based on previously reported data in humans. The model represented each tissue as a two‐compartment model—both extracellular and intracellular compartment wherein each intracellular compartment contained a comprehensive metabolic model to the ultimate active metabolite TN. Global sensitivity analyses and Monte‐Carlo simulations were conducted to assess which parameters and how highly sensitive ones impacted peripheral blood mononuclear cells and intracellular lung TN profiles. Finally, clinical multiple‐dose regimens indicated that minimum lung intracellular TN concentrations ranged from ~ 9 uM to 4 uM, which suggest current regimens are effective based on in vitro half‐maximal effective concentration values. The model can be used to explore tissue drug disposition under various conditions and regimens, and expanded to pharmacodynamic models.
Dispersal syndromes drive the formation of biogeographical regions, illustrated by the case of Wallace’s Line
Authors: White Alexander E. , Dey Kushal K. , Stephens Matthew , Price Trevor D. 
Published: January 2021

AbstractAimBiogeographical regions (realms) reflect patterns of co‐distributed species (biotas) across space. Their boundaries are set by dispersal barriers and difficulties of establishment in new locations. We extend new methods to assess these two contributions by quantifying the degree to which realms intergrade across geographical space and the contributions of individual species to the delineation of those realms. As our example, we focus on Wallace’s Line, the most enigmatic partitioning of the world’s faunas, where climate is thought to have little effect and the majority of dispersal barriers are short water gaps.LocationIndo‐Pacific.Time periodPresent day.Major taxa studiedBirds and mammals.MethodsTerrestrial bird and mammal assemblages were established in 1‐degree map cells using range maps. Assemblage structure was modelled using latent Dirichlet allocation, a continuous clustering method that simultaneously establishes the likely partitioning of species into biotas and the contribution of biotas to each map cell. Phylogenetic trees were used to assess the contribution of deep historical processes. Spatial segregation between biotas was evaluated across time and space in comparison with numerous hard realm boundaries drawn by various workers.ResultsWe demonstrate that the strong turnover between biotas coincides with the north‐western extent of the region not connected to the mainland during the Pleistocene, although the Philippines contains mixed contributions. At deeper taxonomic levels, Sulawesi and the Philippines shift to primarily Asian affinities, resulting from transgressions of a few Asian‐derived lineages across the line. The partitioning of biotas sometimes produces fragmented regions that reflect habitat. Differences in partitions between birds and mammals reflect differences in dispersal ability.Main conclusionsPermanent water barriers have selected for a dispersive archipelago fauna, excluded by an incumbent continental fauna on the Sunda shelf. Deep history, such as plate movements, is relatively unimportant in setting boundaries. The analysis implies a temporally dynamic interaction between a species’ intrinsic dispersal ability, physiographic barriers, and recent climate change in the genesis of Earth’s biotas.
Cell count‐based parameters and algorithms for thalassaemia trait screening in the southern Chinese population
Authors: Xu Jialong , Yang Yeru , Zhou Huanbin , Huang Xiaoxin , Chen Bizhen , Chen Nuan , Wu Yinge 
Published: January 2021

AbstractIntroductionThalassaemia trait (TT) is potential to be missed clinically, especially normocytic thalassaemia. We aimed to establish discriminant functions (DFs) and an algorithm for detecting microcytic or normocytic TT in epidemiological screening.MethodsThe receiver operating characteristics (ROC) curve analysis was used to determine the diagnostic performance of the proposed formulas in differentiating TT and nonthalassaemia (non‐TT). DFs combined the two blood count parameters with the highest performance, based on the area under the curve (AUC) value, into mathematical formulas, using logistic regression. The diagnostic efficacy of DFs was subsequently evaluated in 761 participants, and reliability (including adjusted agreement [AA] and Kappa values) and validity (including sensitivity, specificity, likelihood ratio and Youden's Index) were calculated.ResultsAmong microcytic participants, the proposed DFs showed good diagnostic performance (in females: AUC = 0.892 [DF1 = 0.015 × RDW‐CV/RBC − 0.096 × RDW‐SD/RBC + 1.29], in males: AUC = 0.861 [DF2=−0.025 × RDW‐SD/RBC − 0.035 × MCV/RBC + 1.415]). Youden's Index, AA and Kappa values for microcytic TT detection were 0.72, 0.86, and 0.72 and 0.63, 0.81 and 0.63 for females and males, respectively. In normocytic participants with RDW‐CV/RBC ≤ 3.54, DF3=−0.38 × MCH−0.02 × MCHC+17.37 achieved AUC = 0.857 in females, whereas DF4 = 0.007 × MCV−0.113 × MCH+2.829 achieved AUC = 0.969 in males. The Youden's Index, AA and Kappa values for the proposed DFs for thalassaemia detection were 0.69, 0.84 and 0.67 in females, 0.76, 0.91 and 0.71 in males, respectively.ConclusionThe proposed DFs performed well in the detection of TT among participants with microcytic and normocytic parameters and could be utilized in epidemiological study for TT.