bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of the Comprehensive ICF Core Set for Multiple Sclerosis: A Turkish clinical perspective
Authors: Ortabozkoyun Özge , Kesikburun Bilge , Füsun Köseoğlu Belma , Ergün Ufuk , İnan Levent 
Published: December 2024

Objectives: The aim of this study was to evaluate the results of the construct validity of the Comprehensive International Classification of Functioning, Disability and Health (ICF) Core Set for Multiple Sclerosis (MS) and to identify the impact of MS on specific health domains according to the ICF categories in Turkish individuals.
Patients and methods: Between December 2011 and December 2012, a total of 150 individuals with MS (69 males, 81 females; mean age: 39.8±8.0 years; range, 19 to 52 years) who were diagnosed by a neurologist at least six months previously were included. The Comprehensive ICF Core Set for MS was used to assess functioning, disability, and environmental factors in all participants. The Spearman correlation coefficient was used to determine construct validity of the ICF Core Set between the ICF components and disease-specific and general measurements.
Results: The most frequently coded impairments in the body functions component were b280 sensation of pain, b134 sleep functions, b1301 motivations, and b740 muscle endurance functions. The most frequently coded impairments in the body structures component were s110 structure of brain, s120 spinal cord and related structures and s750 structure of lower extremity. A significant problem was documented in 47 of the 53 categories of the activities and participation. Of the 38 categories in the environmental factors, 23 were identified as a facilitator, while 12 categories were identified as a barrier. All body function, structure, activities and participation and environmental factors categories showed a significant correlation with disease-specific and generic measures.
Conclusion: Based on these results, the ICF Core Set may help to determine major facilitators or barriers to functioning and disability and a targeted rehabilitation approach in patients with MS.
Rigid tape dynamic fixation in conservative treatment of acute anterior talofibular ligament tear: A retrospective cohort study
Authors: Du Shenxing , Wei Lihong , Wang Qingliang , Yao Yelin , Xu Ke , Ying Shunchao , Chen Kang 
Published: December 2024

Objectives: This study aims to compare results of rigid tape (RT) dynamic fixation and static fixation in conservative treatment of acute anterior talofibular ligament (ATFL) tear.
Patients and methods: Between September 2021 and December 2021, a total of 91 patients (41 males, 50 females, mean age: 28.5±6.5 years, range, 18 to 40 years) who were diagnosed with ATFL tear and underwent rigid tape (RT) or cast/brace rehabilitation protocol were retrospectively analyzed. The patients were divided into two groups as the RT group (n=36) and the control group (n=55). Follow-up (FU) was performed at six months. Outcomes included pain (Numerical Rating Scale [NRS]), ankle function (American Orthopaedic Foot & Ankle Society [AOFAS] hindfoot score), deviation of center of gravity (DCG), and symptoms after returning to sports.
Results: The difference at each time point of pain, AOFAS, DCG and SRS between the two groups was statistically significant (p<0.05 for all). Only one patient at Week 12 in the RT group had pain in the lateral side of the ankle, while 36 patients at Week 12 and 21 patients (18 in the medial side) at FU had pain in the control group.
Conclusion: Our study results suggest that RT dynamic fixation can accurately lock the ATFL function and may prevent pseudo-stability, so as to quickly repair injury, restore function, and return to sports earlier.
Clinical and ultrasonographic enthesitis assessment before and after anti-tumor necrosis factor treatment in patients with spondyloarthritis
Authors: Asoglu Ibrahim , Palamar Deniz , Akgün Kenan , Er Gunay , Sarı Hidayet 
Published: December 2024

Objectives: This study aimed to clinically and ultrasonographically evaluate enthesitis in patients with spondyloarthritis (SpA) and to determine enthesitis response to anti-tumor necrosis factor (TNF) treatment.
Patients and methods: Thirty-one SpA patients (22 males, 9 females; mean age: 39.4±10.9 years; range, 22 to 60 years) who started anti-TNF treatment due to their high disease activity were included in the cross-sectional prospective study between May 2017 and January 2018. Ankylosing Spondylitis Disease Activity Score, Bath Ankylosing Spondylitis Disease Activity Index, Ankylosing Spondylitis Quality of Life Questionnaire, Bath Ankylosing Spondylitis Functional Index, and Bath Ankylosing Spondylitis Metrology Index were recorded. Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) and Spondyloarthritis Research Consortium of Canada (SPARCC) Enthesitis Score were utilized for clinical enthesitis evaluation. Patients were ultrasonographically evaluated in accordance with the Madrid Sonographic Enthesitis Index (MASEI) by a blinded sonographer. Patients were clinically and ultrasonographically assessed at baseline and in the third month after the treatment.
Results: In the initial evaluation, 24 (77.42%) of the patients had clinical enthesitis, and 30 (96.77%) of the patients had ultrasonographic enthesitis. After anti-TNF treatment, MASES, SPARCC, MASEI-structure, MASEI-thickness, MASEI-bursitis, MASEI-Doppler, MASEI-inflammatory, and MASEI-total scores significantly decreased (p<0.05). There was no significant change in MASEI-damage, MASEI-erosion, and MASEI-calcification scores following the therapy (p>0.05).
Conclusion: Anti-TNF treatment may improve clinical and ultrasonographic enthesitis, particularly inflammatory changes. Erosions and calcifications may not ameliorate after three months of anti-TNF treatment.
Effect of diaphragmatic breathing training with visual biofeedback on respiratory function in patients with multiple rib fractures: A randomized-controlled study
Authors: Shin Ho Jeong , Son Ho Hee 
Published: December 2024

Objectives: The aim of this study was to investigate the effect of diaphragmatic breathing training with visual biofeedback on respiratory function in patients with multiple rib fractures.
Patients and methods: Between June 2021 and October 2021, a total of 16 patients (15 males, 1 female; mean age: 49.50±11.85 years; range, 25 to 66 years) who were diagnosed with multiple rib fractures were randomly assigned into two groups as the control group (CG, n=8) and the visual biofeedback group (VBG, n=8). The effect of each diaphragmatic breathing training on respiratory function was evaluated before and after eight interventions. For respiratory function, pulmonary function test was used to measure pulmonary function and respiratory muscle strength, and the Pain, Inspiratory capacity, Cough (PIC) score was used to evaluated pain, inspiratory capacity, and cough ability.
Results: In both groups, the pulmonary function representing the ratio of measurements to predicted values of both forced vital capacity (CG mean difference=25.37±4.58, p=0.002, VBG mean difference=24.25±3.96, p=0.007) and forced expiratory volume in 1 sec (CG mean difference=32.38±5.7, p=0.002, VBG mean difference=26.15±5.73, p< 0.001) increased significantly. The maximal inspiratory (CG mean difference=14.00±0.35, p=0.002, VBG mean difference=20.5±6.26, p=0.009) and expiratory pressure (CG mean difference=43.72±29.44, p=0.034, VBG mean difference=25.76±6.78, p=0.015), the indicators of respiratory muscle strength, increased significantly in both groups. The PIC score, which evaluated pain, inspiratory capacity, and cough ability, also increased significantly in both groups (CG mean difference=1.63±0.26, p≤0.001, VBG mean difference=3.13±0.19, p< 0.001). The change of PIC score after intervention did not significantly differ between the groups (F=1.439, p=0.250); however, there was a significant difference over time (F=38.476, p< 0.001). The change of PIC scores differed over time between the groups (F=2.806 p=0.011).
Conclusion: Diaphragmatic breathing training and diaphragmatic breathing training with visual biofeedback can improve pulmonary function, respiratory muscle strength, pain, inspiratory capacity, and cough ability in patients with multiple rib fractures.
The efficiency of mirror therapy in peripheral nerve injuries
Authors: Kablanoğlu Serkan , Sade Ilgın , Çekmece Çiğdem , Özdin Gül , Buluç Levent , Dursun Nigar 
Published: December 2024

Objectives: The purpose of this study was to investigate the effectiveness of mirror therapy on pain, sensory, and functional development in addition to conventional rehabilitation and occupational practices in patients with a peripheral nerve injury in the hand.
Patients and methods: Twenty-six patients with peripheral nerve injury in the hand were included in this randomized controlled study between November 2017 and May 2018. The patients were randomly assigned to the mirror group (n=14) and the control (n=12) group. Both groups received conventional therapy in our clinic for 45 min a day during weekdays for six consecutive weeks. The mirror group received an additional 10-15 min of visual mirror therapy. Visual Analog Scale (VAS), Duruöz Hand Index, Quick Disabilities of the Arm, Shoulder, and Hand, Jebsen hand function test, and Semmes-Weinstein monofilament test were used for the assessment of pain, hand function, and sensation of the patients at baseline and after treatment. The handgrip strength of the patients was measured with a dynamometer.
Results: A total of 20 patients (17 males, 3 females; mean age 31.9±16.5, range 16 to 65 years) completed the study, with 10 in each group. Statistically significant improvement was detected in hand skill functions, such as page-turning (p=0.004), backgammon packing (p=0.023), and heavy object lifting (p=0.029) in the mirror group. A statistically significant decrease was found in total scores of VAS after treatment in both groups (p<0.05).
Conclusion: The results imply that mirror therapy integrated with conventional rehabilitation may aid additional benefits on hand functions in peripheral nerve injury. These results demonstrate that mirror therapy can be used in addition to the rehabilitation program of patients with peripheral nerve injury.
The epidemiology of osteoporosis in Türkiye: A comprehensive analysis using the e-Nabız database
Authors: Mahir Ülgü Mustafa , Birinci Şuayıp 
Published: December 2024

Objectives: The study aimed to define the epidemiology of osteoporosis and low bone mass based on bone mineral density at the femoral neck and the lumbar spine in adults 50 years and older in Türkiye.
Patients and methods: The retrospective study included all patients diagnosed with osteoporosis with a bone mineral density scan between January 2016 and May 2023 in the e-Nabız database, a government-run online healthcare database including over 68 million of active users. The data was categorized according to patient demographics, presentation age (0-17, 18-64, and >65 years), geographic regions, and healthcare levels.
Results: A total of 4,253,039 patients (723,863 [17.0%] males, 3,529,176 [83.0%] females) were diagnosed with osteoporosis. Of the patients, 2,432,607 (57.2%) belonged to the 18-64 years age group, 1,783,690 (41.9%) were in the >65 years group, and 36,742 (0.9%) were in the 0-17 years group. The mean age at presentation was 61.1±14.4 (range, 0 to 110) years. The Marmara region had the highest number of cases with 1,330,325 (31.3%), and the Aegean region had the lowest with 194,009 (4.6%). Istanbul had the highest rate of osteoporosis as a province (18.4%), followed by Ankara (7.5%). The lowest rates were recorded in Bayburt (0.0%) and Tunceli (0.1%), respectively.
Conclusion: Registry studies provide reliable information in epidemiological studies. In this study, the first of its kind in Türkiye, we reported the geographical distribution of osteoporosis. As expected, there were more osteoporosis patients in the more densely populated areas of the country. Secondary and tertiary care centers had more entries compared to primary care centers. The annual incidence of osteoporosis showed a declining trend over the years.
Pain types and risk factors in post-COVID-19
Authors: Ketenci Ayşegül , Zure Mert , Merih Akpınar Fatma , Soluk Özdemir Yelda , Balbaloğlu Özlem , Serdar Akaltun Mazlum , Erden Ender , Çağlıyan Türk Ayla , Damla Korkmaz Merve , Metin Ökmen Burcu , Altındağ Özlem , Soyupek Feray , Yakşi Elif , Sindel Dilşad , Sezgin Nalan , Ustaömer Kübra , Nur Kesiktaş Fatma , Dere Didem , Güneş Şevket , Medin Ceylan Cansın , Sonel Tur Birkan , Evcik Deniz 
Published: December 2024

Objectives: This study aims to accurately evaluate pain lasting longer than three months and falls under the category of chronic pain and to determine the risk factors to follow up and treat properly and to develop appropriate diagnostic and treatment algorithms.
Patients and methods: Between March 2021 and December 2021, a total of 437 patients (162 males, 275 females; mean age: 44±14.6 years; range, 12 to 82 years) who were referred to the participating centers due to pain complaints and were diagnosed with post-COVID-19 condition according to the criteria defined by the World Health Organization (WHO) were included in the study. The patients were divided into three groups as nociceptive pain, neuropathic pain, and central sensitization, based on the physician's clinical evaluation and the Self-Report Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) and Central Sensitization Inventory scores.
Results: The most common diagnosis was nociceptive pain followed by central sensitization. Patients with nociceptive pain had less pain. It was found that not exercising regularly, having a chronic disease and being a woman were risk factors for central sensitization, having thyroid disease before COVID-19, and defining the current pain as very severe were risk factors for neuropathic pain.
Conclusion: In the evaluation of post-COVID-19 pain, neuropathic pain and central sensitization should be also considered in addition to nociceptive pain and the severity of pain, systemic diseases and physical activity should be questioned.
Telehealth and telemedicine in Latin America: a scoping review
Authors: Hechenleitner Carvallo Marcela , Ibarra Peso Jacqueline , Zapata-Toloza Rayen , Barra Andalaft Camila 
Published: December 2024

Introduction: telehealth and telemedicine have emerged as crucial tools in healthcare, especially during the COVID-19 pandemic. This study aims to analyze the evolution and impact of these practices in Latin America from 2019 to the present. The objective of this review is to evaluate the current state of telehealth and telemedicine in Latin America, identifying benefits, challenges, and areas for improvement.Methods: a systematic review was conducted using the PRISMA 2020 methodology. Databases such as Scopus, WoS, PubMed, and Google Scholar were consulted, applying a search algorithm that combined relevant terms. Inclusion criteria were established for articles published between 2019 and 2024 in English and Spanish, prioritizing those with open access.Results: although telemedicine increased during the pandemic, its use declined considerably afterward. Cultural, legislative, and technological gap factors are believed to be the main causes of this decline. Conclusions: the pandemic accelerated the adoption of telehealth in Latin America, revealing its potential to improve access and quality of health care. However, challenges related to infrastructure and training of health personnel persist. It is recommended to strengthen public policies and the regulatory framework to ensure the sustainability and effectiveness of these services in the future.
Deep learning techniques for breast mass malignancy classification on digital mammography
Authors: Coto Santiesteban Ariel , Garzón Cutiño Lisbel , Valdés Santiago Damian 
Published: December 2024

Introduction: Breast cancer is one of the most common type of cancer with a high mortality rate. Mammography is widely used to identify breast cancer. Computer Aided Diagnosis systems are used for automatic detection of breast lesions. Methods: We propose and evaluate a deep learning model, called VGG16-C300, for breast mass malignancy classification. CBIS-DDSM dataset was used for training and evaluation. Image contrast enhancement methods like CLAHE and Mean Blur where previously applied to regions of interests. Results: The trained model achieved and area under the curve of 0.80, after 10 iterations of a 5-fold Cross-Validation. Conclusions: VGG16-C300 could be used as a component in a computer-aided diagnosis system for breast cancer detection
Establishment of an Integrated Development Post (POSBINDU) for Non-Communicable Diseases (Ncds) in the Community of Karunrung Subdistrict, Makassar City
Authors: Muhasidah Muhasidah , Iwan Iwan , Ahmad Abd Kadir , Hartati Hartati , Baharuddin Baharuddin 
Published: December 2024

A situational analysis based on research conducted by Muhasidah et al. (2023) on 128 respondents showed that more than 50% of them suffered from Non-Communicable Diseases (NCDs). Among these, 67 respondents had hypertension, with 32 not taking hypertension medication regularly and 8 not taking medication at all. The irregular intake of antihypertensive drugs can lead to complications such as stroke, heart abnormalities, and kidney disease. Makassar City recorded a total of 5,632 hypertension cases (8.9%), the highest prevalence in South Sulawesi. Karunrung Subdistrict, under the working area of the Kassi-kassi Community Health Center, had the highest cases of hypertension in Makassar City. The implementing partner's priority problem was the high rate of hypertension in the area, along with the absence of an Integrated Development Post (Posbindu) for NCDs. The target partner community also lacked awareness about the importance of consistently taking antihypertensive medication to prevent complications such as stroke, heart abnormalities, and kidney disorders. The objectives of this activity were to establish an Integrated Development Post (Posbindu) for NCDs, increase the target partner's knowledge and ability to conduct Posbindu activities, educate families about the prevention and management of NCDs, and reduce the incidence of NCDs by 20–30% within one year. The proposed solutions included training target groups, providing guidebooks, implementing the five-table Posbindu NCD activities, encouraging the community to participate in weekly physical exercise for NCDs, and distributing guidebooks on NCDs and Posbindu activities prepared by the community service team. The partner's contribution included providing a permanent facility that could be used as the Posbindu NCD. The expected outcomes of this activity were the establishment of a Posbindu NCD in RW 08, increased knowledge among target partners from 50% to 80%, the initiation of weekly NCD exercise sessions, and a reduction in NCD cases by 20–30% during the year. The community service results showed significant improvement in knowledge, understanding, and attitudes among cadres and individuals with NCDs. A Posbindu was successfully established with the help of the community service team and implementing partners, including the Kassi-kassi Health Center. The sustainability of the Posbindu activities will be handed over to the implementing partners, namely the Kassi-kassi Health Center and the local community groups (Majelis Taklim).
Risk Factors for Anemia in the Event of Low Birth Weight (LBW)
Authors: Nurrohmah Anjar , Indarwati Indarwati , Rahmawatie Diyah 
Published: December 2024

Background: The prevalence of LBW is still high in the world and also in Indonesia. Karanganyar Regency Health Profile (2021) The IMR rate in Karanganyar Regency in 2021 is 8.3 per 1000 live births. If a pregnant woman experiences anemia, this will have an impact on the pregnancy process itself, both on the mother and the fetus. Various factors contribute to LBW. In general, these factors can be viewed from the mother's and baby's side, placental factors and environmental factors. Factors for LBW originating from babies include premature birth and delayed fetal growth. The factor of transporting nutrients and oxygen from mother to fetus is very important in the process of fetal growth and development in the womb. Among them are related to complications and illnesses experienced by the mother during pregnancy. Method: Descriptive quantitation using the method of searching medical records for LBW babies. Results: the majority of respondents were aged 20-35 years (81%), the majority of respondents had secondary education (72%), the majority of mothers did not work (53%), a small proportion of mothers with LBW babies had anemia.
United Nation Security Council Legal Politics Against Countries Violating International Humanitarian Law
Authors: Syah Nurijlal Hafizh , Sudiro Ahmad 
Published: December 2024

The United Nations Security Council is a forum created by the United Nations based on the United Nations Charter which contains good and noble goals for the creation of peace and harmony among countries in the international region. The United Nations Security Council with all the specificities given by the United Nations makes this association an international law enforcer for countries that violate international customs and norms. However, not in line with the purpose and function of the establishment of the United Nations Security Council, often the Security Council shows a political-legal attitude that is contrary to its duties and functions, the use of veto privileges that should be used for countries that violate the provisions of international humanitarian law is instead used to exert political emphasis in order to achieve a global domination. Then the question is about the practice of legal provisions applied by the United Nation Security Council in imposing international sanctions against countries in conflict and the legal responsibility of the UN Security Council against countries that violate the provisions of humanitarian law in armed conflicts. This study aims to find out and observe the provisions of international law applied by the United Nation Security Council (UNSC) in imposing international sanctions against countries in conflict, as well as to know, study and analyze the responsibility of the UN Security Council in imposing sanctions against countries that violate the provisions of humanitarian law in armed conflicts. Furthermore, this study uses a normative research method with Primary Legal Materials in the form of expert interviews and secondary legal materials in the form of international legal agreements and international regulations. That in terms of practice, the UN Security Council needs to carry out its duties and functions in accordance with the regulations stipulated in the UN Charter and prioritize the principles that are upheld in the midst of the United Nations by always adhering to its legal responsibilities.
Accountability for the Crime of Theft Committed with Aggravation in Bandar Lampung (Study Decision Number 69/Pid.B/2023/PN.Tjk.)
Authors: Seregig I Ketut , Ainita Okta , Wahyu R Amar 
Published: December 2024

The crime of theft with this aggravation is regulated in Article 363 of the Criminal Code with a maximum penalty of imprisonment of seven years. This act of theft is a type of theft that is different from other types of criminal acts of theft. Thus, aggravated theft is theft which basically contains elements of theft, and because of the addition of other elements, the risk of punishment becomes more severe. Aggravated theft is included in special theft because this theft is carried out in a certain way or under certain circumstances so that it is more serious. In this case, the author takes an example of a criminal case of theft committed with aggravation in Bandar Lampung, which was committed by the defendant M. Ziaulhaq Adivar als Ezzi Adivar als MJ Bin Suhendra.