bluuebunny/crossref_metadata_2025_split huggingface dataset:
Priming versus propagating: distinct immune effects of an alpha- versus beta-particle emitting radiopharmaceutical when combined with immune checkpoint inhibition
Authors: Kerr Caroline P. , Jin Won Jong , Liu Peng , Grudzinski Joseph J. , Ferreira Carolina A. , Rojas Hansel Comas , Oñate Alejandro J. , Kwon Ohyun , Hyun Meredith , Idrissou Malick Bio , Schwartz René Welch , Vera Jessica M. , Clark Paul A. , Takashima Maya , Erbe Amy K. , Shea Amanda G. , Powers Maria , Pinchuk Anatoly N. , Massey Christopher F. , Choi Cynthia , Hernandez Reinier , Bednarz Bryan P. , Ong Irene M. , Weichert Jamey P. , Morris Zachary S. 
Published: December 2024

ABSTRACTRadiopharmaceutical therapy (RPT) enhances tumor response to immune checkpoint inhibitors (ICI) in preclinical models, but the effects of different radioisotopes have not been thoroughly compared. To evaluate mechanisms of response to RPT+ICI, we used NM600, an alkylphosphocholine selectively taken up by most tumors. Effects of90Y-,177Lu-, and225Ac-NM600 + ICIs were compared in syngeneic murine models, B78 melanoma (poorly immunogenic) and MC38 colorectal cancer (immunogenic).90Y-/177Lu-/or225Ac-NM600 delivering 2 Gy mean tumor dose promoted tumor regression and improved survival when combined with ICIs in syngeneic mice bearing B78 or MC38 tumors. Regardless of the administered isotope, this combination was optimized with early ICI administration (days -3/0/3) relative to day 1 RPT.90Y-NM600+ICI produced the greatest anti-tumor response for MC38, whereas high linear energy transfer (LET) alpha particle radiation from225Ac-NM600+ICI was most effective against poorly immunogenic B78 tumors. Flow cytometry and single cell RNA and T cell receptor (TCR) sequencing illuminated distinct mechanisms of90Y- or177Lu-NM600 in promoting expansion of existing adaptive immunity and of225Ac-NM600 in promoting immune priming when combined with ICI. Antitumor immune response can be achieved with appropriate application of α- or β- emitting RPT in combination with ICIs in diverse murine tumor models.
Epithelium Stratifies via Nucleation and Growth Induced by Foam-Geometric Instability
Authors: Fukamachi Shuya , Datta Razib , Wuergezhen Duligengaowa , Ichikawa Takehiko , Yagasaki Rei , Horiguchi Shuhei A. , Leeaw Phoebe , Omachi Kohei , Sada Aiko , Imayoshi Itaru , Kajiwara Kentaro , Hiraiwa Tetsuya , Oshima Masanobu , Fukuma Takeshi , Fujiwara Hironobu , Okuda Satoru 
Published: December 2024

AbstractThe epithelium undergoes stratification, transitioning from a monolayer to a multilayer structure, across broad phenomena. Recent studies have identified several cell behaviors as triggers, including junctional tension, cell density and geometry, and topological defects. However, how these factors drive stratification throughout the entire epithelium remains poorly understood. Here, we report a mechanism underlying epithelial stratification that mirrors the physics of phase transition. Combining cell culture with three-dimensional vertex modeling, we demonstrate that epithelium stratifies via nucleation-growth process, i.e., multilayer origins dispersedly appear and expand across the epithelium via unordered intermediate states. This process is akin to a phase transition induced by a mechanical instability inherent in the foam-like geometry of the epithelium. Moreover, this concept applies to embryonic skin development and malignant transformation of cancer. These findings conceptualize epithelial stratification as a form of a phase transition governed by nucleation and growth, offering a physical perspective on various epithelial developments.
Local mutual funds, corporate community investment and shareholder value
Authors: Hwang Hyoseok (David) , Kim Hyun Gon , Kim Jung Yeun (June) 
Published: December 2024

PurposeThis paper shows that local mutual funds lead firms to engage in corporate social activities locally – corporate community investment (CCI).Design/methodology/approachUsing an extensive US sample of 3,691 firms for the period of 2005–2018, we find that mutual funds investing in local firms tend to increase CCI. To address endogeneity concerns, we employ an instrumental variable (IV) approach with the S&P 500 Index and Russell 1000/2000 Indexes, which suggests a causal effect of local mutual funds on CCI. Our robustness tests include alternative measures of CCI and local ownership as well as different samples using sole-HQ firms, time lags and a matching sample analysis. In addition, we employ alternative approaches for causality tests.FindingsWe find that mutual funds investing in local firms tend to increase CCI. In addition, our results indicate that CCI tends to increase firm performance measured with Tobin’s Q and operating cash flow, especially in the consumer-oriented industries where customer relations are critical. The findings imply that CCI is considered as building reputational and relationship capital in communities (i.e. strategic intangibles related to stakeholders). Local mutual funds can help firms develop such strategic intangibles that promote shareholder value.Originality/valueOur study is the first to investigate the role of local institutional shareholders as a driving force of a firm’s community investments.
Strategies to enhance radio frequency identification (RFID) technology applications in the construction industry
Authors: Wijerathna M.R.D.P. , Waidyasekara K.G.A.S. , Atapattu A.M.D.S. 
Published: December 2024

Purpose
The implementation of Radio Frequency Identification (RFID) technology has been initiated by many countries for construction industry applications due to its peculiar benefits. However, the successful implementation of the RFID technology has been hindered due to numerous barriers that are specific to the construction sector. Therefore, this study aims to propose strategies to overcome barriers that constitute significant obstructions to RFID adoption in the construction industry.

Design/methodology/approach
This study adopted an exploratory mixed-method approach to attain the research aim. The survey was followed by 11 individual interviews conducted with experts and the findings were analysed using content analysis. The questionnaire survey that was carried out as a part of the research had a response rate of 80% and collected data were analysed using Relative Importance Index. To ensure the robustness of the findings, expert validation interviews were conducted to cross-verify and provide deeper insights into the results.

Findings
The high implementation cost of RFID technology was identified as the most significant barrier when implementing RFID technology. Subsequently, strategies were proposed to implement RFID technology based on identified highly significant barriers of RFID. Implementing RFID technology in small-scale construction projects, increasing the collaboration among the countries that have implemented RFID technology and encouraging investors to invest in RFID-implemented projects were mainly proposed to improve the applications of RFID technology in the construction industry.

Originality/value
This study paves the way to identify the RFID technology concept and its barriers and strategies to effectively implement RFID technology in the construction industry. Findings are helpful to the construction industry practitioners to obtain the optimum benefit from the implementation of RFID technology.
Topology optimization of a nonlinear ferrite core for induction heating in injection molding
Authors: Poggiana Giulio , Zorzetto Matteo , Lucchini Francesco , Torchio Riccardo , Forzan Michele , Dughiero Fabrizio 
Published: December 2024

Purpose
Recent progress in additive manufacturing methods alleviated manufacturing constraints on devices. Topology optimization (TO) methods can leverage these reduced limitations and this paper aims to study the use of these algorithms in induction heating for injection molding.

Design/methodology/approach
In this paper, TO is used to reduce the volume of ferrite in an injection molding tool while aiming at maximizing the performance of the device. Characteristics of the proposed solution such as efficiency and power density are compared to the ones of the original device.

Findings
The study shows that it is possible to reduce significantly the amount of ferrite used without impacting the efficiency. The thermal performances of the proposed solution present also slight improvements compared to the original solution.

Originality/value
Optimization algorithms are important for understanding how to design efficient electrical devices. In this paper, the application of TO for injection molding applications presents a new perspective in designing such components.
The luxury consumer knowledge effect: when mature consumers prefer inconspicuous consumption
Authors: Wong Jared , Ho Foo Nin 
Published: December 2024

Purpose
What might lead a luxury consumer to signal with an inconspicuous product? Drawing upon luxury consumer maturity theory, which proposes that mature luxury consumers exhibit a greater preference for inconspicuous luxury goods, this papers aims to consider if consumer field-specific knowledge increases the preference for inconspicuous consumption.

Design/methodology/approach
By measuring and manipulating consumer knowledge via correlational and experimental designs, respectively, the authors probe the association between consumer knowledge and preferences for inconspicuous luxury products.

Findings
This study reports converging evidence suggesting that more knowledgeable (non-)luxury consumers prefer (non-)luxury goods that send inconspicuous signals.

Research limitations/implications
The proposed luxury consumer knowledge effect provides insights into the rise of inconspicuous luxury consumption and offers counterintuitive managerial implications, particularly for marketing communications and advertising.

Practical implications
Inconspicuous luxury brands should engage in an informational sharing approach to their marketing communications, as increasing knowledge may encourage inconspicuous consumption.

Originality/value
While prior work on inconspicuous consumption has addressed the utility of subtle signals and presented a classification of different types of luxury consumers, for instance, the authors instead consider one potential driver of inconspicuous consumption: consumer knowledge. To the best of the authors’ knowledge, this study is also the first to provide empirical support for luxury consumer maturity theory, in addition to examining the boundaries of this framework.
Ergonomic analysis of dynamic working postures among sewing machine operators
Authors: De Silva Charith Dilshan , Dissanayake Piumi , De Silva Nayanthara , Thisakya Geethmi 
Published: December 2024

Purpose
Sewing machine operators face a significant health risk in the form of work-related musculoskeletal disorders (WMSDs). Although the importance of adopting dynamic postures to alleviate musculoskeletal symptoms is researched, a substantial proportion of operators still experience WMSDs. This study aims to fill a gap in the literature by analysing the impact of dynamic posture, as opposed to static ones, on musculoskeletal symptoms among sewing machine operators.

Design/methodology/approach
A quantitative research approach was used for this study. Data were gathered from 1,543 sewing machine operators in Sri Lankan textile and apparel manufacturing sector, encompassing seated, standing and dynamic working postures. The participants were selected using stratified random sampling, and data collection was conducted via a pre-tested, interviewer-administered questionnaire based on the extended translated version of the Nordic Musculoskeletal Questionnaire. To analyse the data, a one-way analysis of variance was performed to examine the impact of current working postures on pain and discomfort, considering various demographic variables such as age and gender.

Findings
The results indicate that 58.24% of sewing machine operators reported suffering from pain/discomfort due to work activities. Individuals in dynamic postures (21%) reported the least pain (52.7%), while majority of female sewing machine operators declared of having pain/discomfort as a result of work activities they perform. However, foot/ankle pain was common across postures. In summary, the discussion reveals the nuanced relationship between working postures and musculoskeletal pain/discomfort among sewing machine operators.

Originality/value
Enhancing ergonomics through dynamic postures has implications that extend beyond the textile and apparel manufacturing industry, offering valuable insights applicable to a wide range of workplace environments. This study highlights the importance of further research, particularly in assessing the effectiveness of ergonomic interventions designed to reduce musculoskeletal symptoms among sewing machine operators. It also underscores the importance of incorporating anthropometric data, adopting a holistic approach that considers factors such as the work environment, equipment design and worker health, and ensuring a more balanced or gender-specific sample in future studies.
A study of mobile learning among adult neo-literates in courses by the Iranian Literacy Movement Organization
Authors: Shafiei Sarvestani Maryam , Javanmard Ali , Samie Mohammad Ebrahim , Biranvand Ali 
Published: December 2024

Purpose
This study aims to explore the impact of mobile learning on educating Iranian adult neo-literates within courses held by Iranian Literacy Movement Organization.

Design/methodology/approach
A concurrent mixed-methods design was used to investigate to what extent the adult neo-literates in Shiraz, Iran, were ready to use mobile phones in their courses. The qualitative section involved merging and summarizing basic themes into organizing themes. The themes were then integrated to create a single global theme.

Findings
The results showed that the participants were ready to embrace m-learning. Instrumentality was the most influential factor contributing to neo-literates’ readiness for m-learning. Findings also showed that from learners’ standpoint, mobile phones presented some unique features, enabling them to integrate elements from both distance and face-to-face courses. They also believed that mobile phones or other information and communications technology gadgets provided better opportunities for learning, although they fall short of fully replacing human instructors.

Research limitations/implications
The limitations of the study were the participants’ limited familiarity with the research procedure and the impossibility of holding joint gatherings at specific locations.

Originality/value
This applied study helps the literacy movement to take strong steps toward creating an educational environment that guarantees learning anytime and anywhere for its learners.
Annual report readability and financial reporting quality: the moderating role of information asymmetry
Authors: Thanh Dong Nguyen , Thi Mien Thuy Cao , Khuong Nguyen Vinh , Le Anh Huu Tuan 
Published: December 2024

Purpose
Drawing from agency and comprehension theories, this paper aims to examine the influence of annual report readability (ARR) on financial reporting quality (FRQ), with a focus on how information asymmetry moderates this relationship.

Design/methodology/approach
The study uses a sample of 467 listed firms in Vietnam from 2015 to 2021. To analyze the relationship between ARR and FRQ, this paper employs a Generalized Method of Moments (GMM) regression, incorporating information asymmetry as a moderating factor.

Findings
The research findings show that ARR has a positive and significant impact on the FRQ of Vietnamese-listed firms. This paper also finds that information asymmetry significantly and partially moderates the relationship between ARR and FRQ. Specifically, ARR can help alleviate the level of information asymmetry and contributes to improved FRQ.

Practical implications
From a practical perspective, this paper provides empirical evidence for managers, investors and related government departments to evaluate the effects of ARR and offers regulators a method to help improve the transparency of the stock market. More importantly, the results of this study have reference value for scholars and practitioners in developing countries like Vietnam.

Originality/value
From a theoretical perspective, our study adds to the growing literature on ARR, expands the scope of ARR research, elaborates on relevant economic consequences of ARR and complements the literature on the determinants of FRQ.
Impact of livestream selling on suppliers’ operational performance: an empirical study on an online retailer
Authors: Li Xin , Pu Tianlong , Qi Yinan 
Published: December 2024

PurposeLivestream selling is becoming an increasingly popular practice adopted by online retailers to develop a consumer-centric supply chain (CCSC). It improves consumer experience by integrating chat, watch and purchase functions, while also altering consumer behaviors by increasing impulse purchases. Online retailers’ responses to this change potentially impact suppliers’ operational processes. This study aims to empirically examine how livestream selling affects suppliers’ operational performance in terms of lead time and how suppliers’ product variety and order fulfillment capabilities moderate such an impact.Design/methodology/approachUsing data from a leading online retailer in China, the authors use a least squares model with fixed effects to test the relationships. Both the two-stage instrumental variable model and the two-stage Heckman model are used to address potential endogeneity in this study.FindingsThe findings show that retailers’ usage of livestream selling can increase suppliers’ lead time. Furthermore, the negative impact is enhanced when a supplier has a higher level of product variety or a weaker order fulfillment capability.Originality/valueThis study explores how livestream selling alters consumer behavior, adversely affecting upstream suppliers’ operational performance. It underscores the need for a CCSC approach across all tiers, not just those closest to consumers. To achieve this, the research suggests that suppliers must align their capabilities with retailers’ consumer-centric practices to develop a CCSC, particularly by improving order fulfillment capability and cautiously expanding their product variety in livestream selling. The research further highlights the importance for retailers to consider changes in lead time to enhance the application of traditional inventory theory in the context of livestream selling.
Increasing the attitudes toward sustainable development through mindfulness: an innovative approach for higher education institutions
Authors: Plietzsch Sina , Brunmayr Simon , Brunner Sabine , Lehmann Claudia 
Published: December 2024

Purpose
The paper aims to examine mindfulness as innovative approach to foster the attitudes toward sustainable development among future professionals within higher education institutions.

Design/methodology/approach
The paper highlights a quasi-experiment with 36 future professionals to explore the interrelatedness of mindfulness with attitudes toward sustainable development. This included an eight-week Mindfulness-Based Stress Reduction course with a pre-, post- and longitudinal test.

Findings
The study revealed that the training of mindfulness significantly increased the dispositional mindfulness and the overall attitude toward sustainable development of future professionals. Furthermore, their slope of state mindfulness significantly predicted this increase.

Originality/value
The novelty of the paper lays within the operationalization of mindfulness which aims to train the inner development instead of solely imparting knowledge about education for sustainable development.
Are universities engaging in social washing? Rethinking the presentation of university sustainability reports
Authors: Lee Yi-Chih 
Published: December 2024

Purpose
The social dimension of sustainable development has garnered increasing attention. As universities embrace their social responsibility and consider the interests of various stakeholders, the potential issue of social washing has emerged as a critical topic. This study aims to investigate the presence of social washing in university sustainability reports.

Design/methodology/approach
The study examines three key stakeholder elements: full-time faculty salaries, weekly teaching hours for full-time faculty and hourly wages for part-time faculty. A content analysis was conducted on the 2022 sustainability reports published by all private universities registered in Taiwan.

Findings
Results indicate that only 30% of private universities published independent sustainability reports for 2022, and of those, only 62.5% adhered to global reporting initiative guidelines. The study raises concerns about selective disclosure and the concealment of negative information, suggesting the possibility of social washing. This investigation offers an overview of social washing in the sustainability reports of higher education institutions, thereby contributing to the academic discourse on comprehensive and transparent communication with stakeholders.

Social implications
Universities should take into account the interests of stakeholders and embrace greater social responsibility in their sustainability initiatives. This study analyzes the content of university sustainability reports and encourages higher education institutions to foster balanced communication with their stakeholders.

Originality/value
Social washing is difficult to detect. This study uses objective indicators to assist higher education institutions in identifying potential social washing behaviors and provides guidance for universities to avoid misleading communication in their sustainability reports.