bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of velocity loss during squat training on neuromuscular performance
Authors: Rodríguez‐Rosell David , Yáñez‐García Juan Manuel , Mora‐Custodio Ricardo , Sánchez‐Medina Luis , Ribas‐Serna Juan , González‐Badillo Juan José 
Published: April 2021

This study aimed to compare the effects of three resistance training (RT) programs differing in the magnitude of velocity loss (VL) allowed in each exercise set: 10%, 30%, or 45% on changes in strength, vertical jump, sprint performance, and EMG variables. Thirty‐three young men were randomly assigned into three experimental groups (VL10%, VL30%, and VL45%; n = 11 each) that performed a velocity‐based RT program for 8 weeks using only the full squat exercise (SQ). Training load (55–70% 1RM), frequency (2 sessions/week), number of sets (3), and inter‐set recovery (4 min) were identical for all groups. Running sprint (20 m), countermovement jump (CMJ), 1RM, muscle endurance, and EMG during SQ were assessed pre‐ and post‐training. All groups showed significant (VL10%: 6.4–58.6%; VL30%: 4.5–66.2%; VL45%: 1.8–52.1%; p < 0.05–0.001) improvements in muscle strength and muscle endurance. However, a significant group × time interaction (p < 0.05) was observed in CMJ, with VL10% showing greater increments (11.9%) than VL30% and VL45%. In addition, VL10% resulted in greater percent change in sprint performance than the other two groups (VL10%: −2.4%; VL30%: −1.8%; and VL45%: −0.5%). No significant changes in EMG variables were observed for any group. RT with loads of 55–70% 1RM characterized by a low‐velocity loss (VL10%) provides a very effective and efficient training stimulus since it yields similar strength gains and greater improvements in sports‐related neuromuscular performance (jump and sprint) compared to training with higher velocity losses (VL30%, VL45%). These findings indicate that the magnitude of VL reached in each exercise set considerably influences the observed training adaptations.
Two good interview questions: Mobilizing the ‘good farmer’ and the ‘good day’ concepts to enable more‐than‐representational research
Authors: Sutherland Lee‐Ann 
Published: April 2021

AbstractIn this paper, I assess the utility of two targeted qualitative interview questions: descriptions of a ‘good farmer’ and a ‘good day’, for eliciting rich textual data. Studies where farmers have been asked to describe or define a good farmer have been utilized across a growing range of international contexts in order to identify farmers’ cultural scripts, symbolic capital and social norms. The constitution of a ‘good day’ is new to rural studies but has been employed academically to assess perceptions of well‐being and job satisfaction. I employ document analysis to analyse the multiple uses of the ‘good farmer’ question in the rural studies literature and introduce a contrasting empirical application the ‘good day’ question in a rural case study in the United Kingdom. Findings demonstrate that both interview questions can generate rich textual descriptions of embodied performances. ‘Good farmer’ definitions may also include a moral judgement, whereas the ‘good day’ question specifically yields descriptions of affect. Farmers are reluctant to identify ‘bad farmers’, but asking about a ‘bad day’ can open up discussion of the vulnerabilities of farming life. Both questions are thus suited to more‐than‐representational research, gaining utility from their congruence between common parlance and academic conceptualization.
‘“They Think We’re Just Ghetto, But Nah!”: Re‐Working Young People’s Presence
Authors: Aitken Stuart C. , Pearson Elliot , Herman Thomas 
Published: April 2021

ABSTRACTWith this paper, we document aspects of a year‐long project with 11th‐grade students from a high school in City Heights, San Diego. The students chose to become present, to share their experiences, explore others' understandings of their neighborhood, and collaborate to create an online multi‐media narrative that reflected them and their relations to the neighborhood. Theoretically, we involve a transversal politics that embrace young people's multiplicities of relations. We assume multiculturalism as a foil to engage young people's community presence. We show how the project moved toward a vibrant, layered, networked, and lyrical presence for young people in City Heights.
Too Many Cooks: Bayesian Inference for Coordinating Multi‐Agent Collaboration
Authors: Wu Sarah A. , Wang Rose E. , Evans James A. , Tenenbaum Joshua B. , Parkes David C. , Kleiman‐Weiner Max 
Published: April 2021

AbstractCollaboration requires agents to coordinate their behavior on the fly, sometimes cooperating to solve a single task together and other times dividing it up into sub‐tasks to work on in parallel. Underlying the human ability to collaborate is theory‐of‐mind (ToM), the ability to infer the hidden mental states that drive others to act. Here, we develop Bayesian Delegation, a decentralized multi‐agent learning mechanism with these abilities. Bayesian Delegation enables agents to rapidly infer the hidden intentions of others by inverse planning. We test Bayesian Delegation in a suite of multi‐agent Markov decision processes inspired by cooking problems. On these tasks, agents with Bayesian Delegation coordinate both their high‐level plans (e.g., what sub‐task they should work on) and their low‐level actions (e.g., avoiding getting in each other's way). When matched with partners that act using the same algorithm, Bayesian Delegation outperforms alternatives. Bayesian Delegation is also a capable ad hoc collaborator and successfully coordinates with other agent types even in the absence of prior experience. Finally, in a behavioral experiment, we show that Bayesian Delegation makes inferences similar to human observers about the intent of others. Together, these results argue for the centrality of ToM for successful decentralized multi‐agent collaboration.
Results of food challenge in dogs with cutaneous adverse food reactions
Authors: Shimakura Hidekatsu , Kawano Koji 
Published: April 2021

BackgroundElimination diet trials and food challenge tests remain the gold standard for diagnosing cutaneous adverse food reaction (CAFR) in dogs. However, food challenge tests are difficult to perform owing to a lack of definite information on expected clinical signs and the time frame within which they develop after challenge.ObjectivesTo report the results of the food challenge test carried out in client‐owned dogs under observation.Methods and materialsA retrospective evaluation of the medical records of dogs presenting with pruritus was performed. Skin infections and/or parasites were treated before inclusion in the study. Dogs that underwent an elimination diet with clinical improvement and relapse with food challenge tests were included in this study. A pruritus Visual Analog scale score was recorded as an index of pruritus before and at the end of the elimination diet trial before challenge. The onset of time to relapse of clinical signs and the body sites affected after food challenge testing were recorded by the owners.ResultsWe examined the medical records of 310 dogs with pruritus. Of these, 46 dogs with a diagnosis of CAFR were enrolled in this study. Significant clinical improvement was observed after the elimination diet trial (P < 0.0001). All dogs exhibited pruritus, and none exhibited anaphylaxis after food challenge testing. Among these dogs, 60.9% developed pruritus within 12 h of food challenge. Notably, 23.9% of the dogs developed pruritus within 3–6 h. The limbs exhibited the highest frequency of pruritus (56.5%), followed by the face (26.1%).Conclusions and clinical relevanceThis study is the first to report details of the time to onset of clinical signs and body site affected after food challenge testing in dogs. These results will assist veterinarians and dog owners in the decision‐making process regarding food challenge testing.
Evidence for 40–41 km of dextral slip on the southern Death Valley fault: Implications for the Eastern California shear zone and extensional tectonics
Authors: Pavlis Terry L. , Trullenque Ghislain 
Published: April 2021

Abstract
Recognition of a pair of pre-Neogene markers together with analysis of published data indicate ∼40 km of dextral slip across the southern Death Valley fault zone, California, USA. Stratigraphic overlaps on fault rocks indicate much of the dextral slip predates the late Miocene, placing a significant fraction of the dextral slip in the same time window as regional extension and challenging interpretations that the modern strike-slip system became active post–6–3 Ma. However, these results are consistent with regional evidence that dextral transtension began by ca. 12 Ma.
People with amyotrophic lateral sclerosis and their caregivers: what matters most?
Authors: Brunori Paola , Celani Maria Grazia , Bignamini Angelo Alberto , Carlini Marzia , Papetti Rossella , Ercolani Maria Vittoria , Baiocco Luisa , Armato Gaetano , Cantisani Teresa Anna 
Published: April 2021

ObjectivesThe aim of this study is to collect the perspectives and values of people affected by amyotrophic lateral sclerosis (ALS) and their carers to offer clinicians, researchers and policymakers aspects which are precious in prioritising future research questions and reshaping care service organisations in a participatory approach.Design and settingCohort study using ALS Umbria, the electronic database in Italy.ParticipantsEleven patients and 33 carers who agreed to participate in the study were divided into six focus groups by ‘status’ (patient or carer) and by four severity levels of ‘burden of disease’.MethodsA semiquantitative analysis was undertaken. Each recorded group discussion was transcribed into text file and independently read by two psychologists and two ALS specialists to blindly identify needs, emotions and medical issues, which are the key semantic meanings expressed. Any disagreement in interpretation was resolved through consultation among authors.ResultsCarers pronounced significantly more words related to patient’s disease burden they cared. 40% of subjects expressed the need for ‘assistance’, regardless of the disease burden. ‘Anger’ alone represented more than 1/4 of all expressed emotions and was more common in patients than in carers (73% vs 36%, p=0.077). The most frequent medical issue expressed by 1/3 of participants was ‘difficulty in communication’.ConclusionThis study has given voice to the expectations of those affected by the burden of ALS. ‘Welfare assistance’, ‘anger management’ and resolution of ‘difficulties in communication’ represent issues that need to be analysed in a common prioritised research agenda with sensible and shared outcome measures to implement patient-centred medicine.
Endoscopic management of intentional foreign body ingestion: experience from a UK centre
Authors: Yadollahi Sina , Buchannan Ryan , Tehami Nadeem , Stacey Bernard , Rahman Imbadhur , Boger Philip , Wright Mark 
Published: April 2021

ObjectiveWe report on the increasing incidence and outcomes from intentional foreign body ingestion (iFoBI) presenting to our hospital over a 5-year period. The aim was to assess the impact on services and to identify ways to safely mitigate against this clinical challenge.Design/methodWe performed a retrospective observational study of all patients presenting to a university hospital between January 2015 and April 2020 with iFoBI with a focus on objects swallowed, timing of endoscopy and clinical outcomes.Results239 episodes of iFoBI in 51 individuals were recorded with a significant increase in incidence throughout the study period (Welch (5, 17.3)=15.1, p<0.001), imposing a high burden on staff and resources. Items lodged in the oesophagus were more likely to lead to mucosal injury (p=0.009) compared with elsewhere. Ingested item type and timing of endoscopy were not related to complications (p=0.78) or length of stay (p=0.8). In 12% of cases, no objects were seen at endoscopy.ConclusionIn all except those patients with oesophageal impaction of the object on radiograph, there is no need to perform endoscopic extraction out of hours. A subset of cases can avoid endoscopy with an X-ray immediately prior to the procedure as a significant proportion have passed already. We discuss more holistic approaches to deal with recurrent attendances.
Mortality and high risk of major adverse events in patients with COVID-19 and history of cardiovascular disease
Authors: Tessitore Elena , Carballo David , Poncet Antoine , Perrin Nils , Follonier Cedric , Assouline Benjamin , Carballo Sebastian , Girardin François , Mach Francois 
Published: April 2021

ObjectiveHistory of cardiovascular diseases (CVDs) may influence the prognosis of patients hospitalised for COVID-19. We investigated whether patients with previous CVD have increased risk of death and major adverse cardiovascular event (MACE) when hospitalised for COVID-19.MethodsWe included 839 patients with COVID-19 hospitalised at the University Hospitals of Geneva. Demographic characteristics, medical history, laboratory values, ECG at admission and medications at admission were collected based on electronic medical records. The primary outcome was a composite of in-hospital mortality or MACE.ResultsMedian age was 67 years, 453 (54%) were males and 277 (33%) had history of CVD. In total, 152 (18%) died and 687 (82%) were discharged, including 72 (9%) who survived a MACE. Patients with previous CVD were more at risk of composite outcomes 141/277 (51%) compared with those without CVD 83/562 (15%) (OR=6.0 (95% CI 4.3 to 8.4), p<0.001). Multivariate analyses showed that history of CVD remained an independent risk factor of in-hospital death or MACE (OR=2.4; (95% CI 1.6 to 3.5)), as did age (OR for a 10-year increase=2.2 (95% CI 1.9 to 2.6)), male gender (OR=1.6 (95% CI 1.1 to 2.3)), chronic obstructive pulmonary disease (OR=2.1 (95% CI 1.0 to 4.2)) and lung infiltration associated with COVID-19 at CT scan (OR=1.9 (95% CI 1.2 to 3.0)). History of CVD (OR=2.9 (95% CI 1.7 to 5)), age (OR=2.5 (95% CI 2.0 to 3.2)), male gender (OR=1.6 (95% CI 0.98 to 2.6)) and elevated C reactive protein (CRP) levels on admission (OR for a 10 mg/L increase=1.1 (95% CI 1.1 to 1.2)) were independent risk factors for mortality.ConclusionHistory of CVD is associated with higher in-hospital mortality and MACE in hospitalised patients with COVID-19. Other factors associated with higher in-hospital mortality are older age, male sex and elevated CRP on admission.
Neonatal and early childhood outcomes following maternal anesthesia for cesarean section: a population-based cohort study
Authors: Kearns Rachel Joyce , Shaw Martin , Gromski Piotr S , Iliodromiti Stamatina , Pell Jill P , Lawlor Deborah A , Nelson Scott M 
Published: April 2021

BackgroundThe fetus is vulnerable to maternal drug exposure. We determined associations of exposure to spinal, epidural, or general anesthesia on neonatal and childhood development outcomes during the first 1000 days of life.MethodsPopulation-based study of all singleton, cesarean livebirths of 24+0 to 43+6 weeks gestation between January 2007 and December 2016 in Scotland, stratified by urgency with follow-up to age 2 years. Models were adjusted for: maternal age, weight, ethnicity, socioeconomic status, smoking, drug-use, induction, parity, previous cesarean or abortion, pre-eclampsia, gestation, birth weight, and sex.Results140 866 mothers underwent cesarean section (41.2% (57,971/140,866) elective, 58.8% (82,895/140,866) emergency) with general anesthesia used in 3.2% (1877/57,971) elective and 9.8% (8158/82,895) of emergency cases. In elective cases, general anesthesia versus spinal was associated with: neonatal resuscitation (crude event rate 16.2% vs 1.9% (adjusted RR 8.20, 95% CI 7.20 to 9.33), Apgar <7 at 5 min (4.6% vs 0.4% (adjRR 11.44, 95% CI 8.88 to 14.75)), and neonatal admission (8.6% vs 4.9% (adjRR 1.65, 95% CI 1.40 to 1.94)). Associations were similar in emergencies; resuscitation (32.2% vs 12.3% (adjRR 2.40, 95% CI 2.30 to 2.50)), Apgar <7 (12.6% vs 2.8% (adjRR 3.87, 95% CI 3.56 to 4.20), and admission (31.6% vs 19.9% (adjRR 1.20, 95% CI 1.15 to 1.25). There was a weak association between general anesthesia in emergency cases and having ≥1 concern noted in developmental assessment at 2 years (21.0% vs 16.5% (adjRR 1.08, 95% CI 1.01 to 1.16)).ConclusionsGeneral anesthesia for cesarean section, irrespective of urgency, is associated with neonatal resuscitation, low Apgar, and neonatal unit admission. Associations were strongest in non-urgent cases and at term. Further evaluation of long-term outcomes is warranted.
Interactive effects of acute exercise and carbohydrate-energy replacement on insulin sensitivity in healthy adults
Authors: Johnson-Bonson Drusus A. , Narang Benjamin J. , Davies Russell G. , Hengist Aaron , Smith Harry A. , Watkins Jonathan D. , Taylor Harry , Walhin Jean-Philippe , Gonzalez Javier T. , Betts James A. 
Published: April 2021

This study investigated whether carbohydrate-energy replacement immediately after prolonged endurance exercise attenuates insulin sensitivity the following morning, and whether exercise improves insulin sensitivity the following morning independent of an exercise-induced carbohydrate deficit. Oral glucose tolerance and whole-body insulin sensitivity were compared the morning after 3 evening conditions, involving (1) treadmill exercise followed by a carbohydrate replacement drink (200 or 150 g maltodextrin for males and females, respectively; CHO-replace); (2) treadmill exercise followed by a non-caloric, taste-matched placebo (CHO-deficit); or (3) seated rest with no drink provided (Rest). Treadmill exercise involved 90 minutes at ∼80% age-predicted maximum heart rate. Seven males and 2 females (aged 23 ± 1 years; body mass index 24.0 ± 2.7 kg·m−2) completed all conditions in a randomised order. Matsuda index improved by 22% (2.2 [0.3, 4.0] au, p = 0.03) and HOMA2-IR improved by 10% (–0.04 [–0.08, 0.00] au, p = 0.04) in CHO-deficit versus CHO-replace, without corresponding changes in postprandial glycaemia. Outcomes were similar between Rest and other conditions. These data suggest that improvements to insulin sensitivity in healthy populations following acute moderate/vigorous intensity endurance exercise may be dependent on the presence of a carbohydrate-energy deficit. Novelty: Restoration of carbohydrate balance following acute endurance exercise attenuated whole-body insulin sensitivity. Exercise per se failed to enhance whole-body insulin sensitivity. Maximising or prolonging the post-exercise carbohydrate deficit may enhance acute benefits to insulin sensitivity.
Light-induced manipulation of passive and active microparticles
Authors: Arya Pooja , Umlandt Maren , Jelken Joachim , Feldmann David , Lomadze Nino , Asmolov Evgeny S. , Vinogradova Olga I. , Santer Svetlana 
Published: April 2021

Abstract
We consider sedimented at a solid wall particles that are immersed in water containing small additives of photosensitive ionic surfactants. It is shown that illumination with an appropriate wavelength, a beam intensity profile, shape and size could lead to a variety of dynamic, both unsteady and steady state, configurations of particles. These dynamic, well-controlled and switchable particle patterns at the wall are due to an emerging diffusio-osmotic flow that takes its origin in the adjacent to the wall electrostatic diffuse layer, where the concentration gradients of surfactant are induced by light. The conventional nonporous particles are passive and can move only with already generated flow. However, porous colloids actively participate themselves in the flow generation mechanism at the wall, which also sets their interactions that can be very long ranged. This light-induced diffusio-osmosis opens novel avenues to manipulate colloidal particles and assemble them to various patterns. We show in particular how to create and split optically the confined regions of particles of tunable size and shape, where well-controlled flow-induced forces on the colloids could result in their crystalline packing, formation of dilute lattices of well-separated particles, and other states.

Graphic Abstract
Enhanced Physiological Stress Response in Patients with Normal Tension Glaucoma during Hypoxia
Authors: Dalgaard Line Marie , Vibæk Jeppe , Vohra Rupali , Jensen Lars Thorbjørn , Cvenkel Barbara , Secher Niels H. , Olsen Niels Vidiendal , Kolko Miriam 
Published: April 2021

Purpose. To investigate whether patients with normal tension glaucoma (NTG) show an enhanced stress response to reduced oxygen supply compared to age-matched healthy controls, measured by serum adrenaline and endothelin-1 (ET-1) levels and changes in distal finger temperature. Methods. A thorough clinical characterization of patients with NTG and age-matched controls was performed prior to inclusion in the study. Twelve patients with NTG and eleven healthy controls met the inclusion criteria and were enrolled in the study. All subjects underwent a two-day investigation. Participants were randomly exposed to either hypoxia or normoxia during the first visit. Hypoxia or normoxia was induced for two hours through a tightly fitting face mask. In addition, the peripheral circulation was assessed with a thermographic camera. Blood samples were obtained before, during, and after hypoxia or normoxia to evaluate systemic stress molecules such as catecholamines and ET-1 levels. Results. In patients with NTG, reduced oxygen supply induced an increase in peripheral blood adrenaline (

p

< 0.05) and a decrease during recovery (

p

< 0.01). A difference in distal finger temperature was shown in patients with NTG under hypoxia compared to normoxia (exposure:

p

< 0.05; recovery:

p

< 0.05). Hypoxia induced an increase in peripheral blood ET-1 levels in both groups (NTG:

p

< 0.01; controls:

p

< 0.05). Conclusion. Patients with NTG had an enhanced physiological stress response as a consequence of hypoxia compared with age-matched controls. Although more studies are needed, the present study supports the involvement of vascular risk factors in the pathophysiology of NTG.