bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recruitment Challenges and Strategies for Multimodal Intervention Trials
Authors: Bartley Jenna 
Published: December 2021

Abstract
Determining ways to improve hip fracture recovery in older adults is important, however recruitment of this target population into clinical trials is challenging. Multimodal interventions that target multiple mechanisms of recovery may improve outcomes, but each component presents unique recruitment barriers. While exercise interventions have been shown to be beneficial for hip fracture recovery, offering exercise following completion of conventional physical therapy can be viewed as a burdensome time commitment. Hormone replacement therapy may hold promise for overcoming anabolic resistance, but concern about adverse side effects can also deter participation. STEP-HI is a multisite trial testing whether exercise and testosterone can improve hip fracture recovery in older women. In this talk, recruitment barriers experienced in STEP-HI and strategies employed to overcome these barriers will be discussed. Strategies include: partnering with hospitals, skilled nursing facilities and orthopedic surgeons. providing talks and education materials; and featuring past participant testimonials in recruitment materials.
How Does Testosterone Augment the Anabolic Response to Exercise in Frail Older Adults?
Authors: Bhasin Shalendar 
Published: December 2021

Abstract
Testosterone treatment increases muscle mass, strength, and leg power in menopausal women, hypogonadal men, older men with mobility limitation, COPD and ESRD. Testosterone's effects on muscle mass and strength are augmented by exercise training and growth hormone. Testosterone treatment improves some measures of physical performance, such as stair climbing power and aerobic capacity; the improvements in gait speed have been modest. Testosterone increases muscle mass by inducing the hypertrophy of type 1 and 2 muscle fibers, and by increasing satellite cell number. Testosterone promotes the differentiation of mesenchymal progenitor cells into myogenic lineage and inhibits their differentiation into adipogenic lineage by activating Wnt-target genes, including follistatin that plays an important role in mediating testosterone's effects on the muscle. Testosterone also increases polyamine synthesis in the muscle. Combined administration of testosterone plus multi-component exercise intervention that includes functional training may be needed to improve function and mobility in older adults.
Interpersonal Associations Between Affect and Depressive Symptoms in Persons With Early Dementia and Their Spouses
Authors: Monin Joan , Piechota Amanda , Syed Sumaiyah 
Published: December 2021

Abstract
Positive and negative affect have independent effects on health and occur frequently in close relationships. No research to our knowledge has examined self-reported affective experiences of persons with dementia (PWD) and their spouses and interpersonal associations with their psychological health. Secondary analysis of baseline interviews from a randomized clinical trial testing a stress reduction intervention in 45 couples (n=90) examined whether individuals’ positive and negative affect were associated with their own depressive symptoms (actor effects) as well as their partner’s depressive symptoms (partner effects) and whether these associations differed for PWD and spouses. Actor partner interdependence model results showed that for PWDs and spouses, one’s own positive affect was related to one’s own lower depressive symptoms (B=-3.10, SE=.59, df=58.70, p&lt;.001), and one’s own negative affect was associated with one’s own greater depressive symptoms (B=6.62, SE=.60, df=65.67, p&lt;.001). These effects were independent from each other. Partner effects were not significant.
Presidential Symposium: Physiological vs. Molecular Clocks, Studies From Mice to Humans
Authors: Rogina Blanka 
Published: December 2021

Abstract
Aging is associated with a functional decline in metabolic, physiological, proliferative, and tissue homeostasis leading to deterioration at the organismal level, and an increased risk for disease and death. Genetic, pharmacological and nutritional interventions have been successfully used to preserve metabolic health, which leads to preserved healthspan and extended longevity. However, the rate at which animals in a population become impaired by age-related frailty and disease is highly variable and several aging clocks that measure different age-modulated processes in the organism are being use as potential markers of the rate of aging. These molecular clocks allow to a more accurate quantification of the biological age of animals. Nevertheless, there is still room for further discussion in terms of the strengths and weaknesses of these biomarkers, in order to probe their biological significance, cellular mechanisms, and epidemiological potential to further explore their long-term benefit of increasing healthspan. This symposium will discuss new approaches to delineate physiological versus molecular clocks based on studies in mice and humans. We will also discuss species-specific metabolic mechanisms based on longitudinal studies in mice, monkeys and humans.
The Growing Global Healthy Longevity Ecosystem
Authors: Seoh Thomas 
Published: December 2021

Abstract
The geroscience field has started to grow exponentially in recent decades. This in turn has led to a rapidly emerging global ecosystem of players and nodes that has radiated out into fields from clinical investigation to medical practice to capital markets and startup activity to consumer-facing goods and services, regulations, laws and policies and the general wellness-conscious public. These are still early days, and there is uncertainty and a lack of awareness about the shape and activities of this rapidly growing and evolving community. This presentation will attempt a high-level survey of the current landscape in the hope of promoting awareness and collaborations among diverse, multiple initiatives that can accelerate the field.
The Ties That Bind: How Online and Offline Interactions Affect Social Support and Quality of Life for Older Adults
Authors: Cotten Shelia 
Published: December 2021

Abstract
Though a digital divide still exists, older adults are increasingly using a range of information and communication technologies (ICTs) – smartphones, apps, tablets, and computers – to communicate and engage with social ties. This symposium focuses on modalities of interaction – whether online or offline – that older adults use to interact with social ties. The research projects detailed examine the frequency of different interaction modalities, as well as impacts of these interaction modalities on older adults’ perceptions of social support and quality of life. Kadylak and colleagues focus on social robots and how older adults may engage with this evolving technology to improve social engagement and aging in place. Kim and Fingerman investigate whether daily social media use is associated with same-day negative or positive mood in later life. Xie and colleagues examine older adults’ patterns of both online and offline social interaction during COVID-19, and how older adults perceive these interactions. Schuster and Cotten, using a national sample of individuals aged 65 and older, examine whether social media use may be related to a range of quality of life indicators. Each of these studies provides additional insights into the ways through which older adults interact and communicate with social ties, and potential impacts of the different ways through which they interact, which may provide insights into groups seeking to increase social engagement among older adults in general and during times when social isolation may be exacerbated due to societal stressors, such as pandemics.
Older Adults' Online and Offline Social Interactions During the COVID-19 Pandemic
Authors: Xie Bo , Shiroma Kristina , De Main Atami , Davis Nathan 
Published: December 2021

Abstract
During the COVID-19 pandemic, much of our social interaction has transitioned from in-person to online. This study examined older adults’ social interaction during COVID-19, online and offline. Participants were recruited from community-dwelling older adults in Central Texas. Data collection took place via the telephone during June-August 2020 (N = 200; age range: 65-92 years; Mean: 73.6; SD: 6.33). Participants used a variety of communication modes, including phone or texting (used by 99% of the participants); email (44%); in person (35%); video chat (31%); social media (24%); and postal mail (4%). Most participants (77%) used more than one communication mode. Participants discussed their preferences for and challenges of technology (i.e., smart phones) and its applications (i.e., video chat, telehealth, and social media). Participants’ self-reported experiences ranged from positive (50%), mixed (35%), to negative (15%). These findings will inform policy and community interventions to promote older adults’ social interactions during the pandemic.
Daily Social Media Use, Social Ties, and Emotional Well-Being in Later Life
Authors: Kim Yijung , Fingerman Karen 
Published: December 2021

Abstract
Research has seldom explored older adults’ daily social media use and its interface with ‘offline’ social ties. Using data from the Daily Experiences and Well-being Study (N = 310; Mage = 73.96), we investigated whether more daily social media use was associated with the same-day negative or positive mood in later life, and how these associations varied with older adults’ daily social encounters and social network structure. More daily social media use was associated with less same-day negative mood. Additionally, more daily social media use was associated with less negative mood on days with more in-person encounters, compared to the days with fewer in-person encounters. More daily social media use was also associated with more positive mood for individuals with a relatively small social network, but not for their counterparts. Post-hoc analyses supported a compensatory function of social media for those older adults lacking social connections in their daily lives.
The Impact of Volunteering Motivation for Older Korean Adults on Social Integration and Role Identity
Authors: Kim Meeryoung 
Published: December 2021

Abstract
As life expectancy increases, older Korean adults need more activities for the next 20 to 30 years after their retirement. Rowe and Kahn indicate active social participation as an area of successful aging. After retirement, older adults uphold a desire to be part of society. This study examines the motivation effects for volunteering on social integration, role identity and volunteer satisfaction. Subjects for this study are 303 older volunteers belonging to the Korean Senior Citizens’ Association throughout South Korea. According to the results, the skills obtained through volunteering had a significant effect on social integration, role identity, and volunteer satisfaction. Value motivation also had a significant effect on social integration, and reinforcement motivation significantly affected role identity. Implications of this study were found to have various effects according to the motivation for volunteering. Therefore, it will be important to understand the older adults’ motives so that they can volunteer accordingly.
Training in Interdisciplinary, Practice-Oriented Minority Aging Research: Honoring the Work of Dr. James Jackson
Authors: Mezuk Briana , Taylor Robert , Thorpe Roland 
Published: December 2021

Abstract
Few scientists had the breadth and depth of scholarship, the keen interest in interdisciplinary scientific collaboration, and the commitment to mentoring the next generation of scientists as Dr. James Jackson. His passing remains a tremendous loss for the field. This symposium, organized by members of the Michigan Center for Urban African American Aging Research (MCUAAAR), which was founded by James over 20 years ago, reflects on the impact of transdisciplinary team science, of the importance of research networks and resource sharing, of the need to center research within practice and community, and of the scientific innovation that comes from integrating conceptual models, data sources, and methodological approaches from seemingly disparate fields. The session is co-chaired by Dr. Robert Taylor, longtime faculty member and current PI of MCUAAAR. The talk by session chair Dr. Briana Mezuk will discuss the ways in which the training approach of Analysis Core has inspired new training programs on integrative methods focused on minority health and disparities. The talk by Dr. Tam Perry will describe the innovations of the Community Liaison and Recruitment Core, including how COVID-19 impacted the activities of the Healthier Black Elder Center. The third talk by Dr. Rodlescia Sneed, a MCUAAAR early-career scientist, provides an example of how this Center supports interdisciplinary minority aging research through her project focused on older adults who have a history of incarceration. Finally, Discussant Dr. Roland Thorpe, a member of the MCUAAAR Advisory Board, will reflect on Dr. Jackson’s legacy of mentorship and collaboration.
Aging Across the Lifespan: Rethinking the David Barker Hypothesis
Authors: Ferrucci Luigi 
Published: December 2021

Abstract
For many years, the scope of geriatric medicine has been the care of older persons affected by multiple disease with the aim of improving their functional status and optimize quality of life. As our knowledge of the mechanisms of aging grows rapidly, it is becoming clear that accomplishing this scope requires taking a life-course perspective. Research have failed to establish a clear-cut distinction between normal aging and pathology leading to the hypothesis that aging is at the root of chronic diseases, and difference in health can be ascribed to different aging rates. Research in model organisms, suggest that aging can be modified with consequent changes on healthspan and longevity. Interventions that modulate aging may ultimately prevent most-age-associated diseases and their consequences. From this perspective, geriatric medicine is the leading and most promising branch of biomedical science. Challenges remain: first, demonstrating that certain interventions slow down the aging rate requires the valid measure of aging, and while many tools were developed, “epigenetic clocks” being the most promising, the underline mechanism that drive their changes with aging and validity in clinical applications are unclear. We do not know whether variability in the rate of biological aging assessed in old age are already detectable in younger individuals and person-specific rates remain constant during life. In 1986, David Barker stated the hypothesis that the period of gestation, characterized by a strong epigenetic imprinting, affects health and wellbeing across life, perhaps by setting the aging rate. Perhaps pediatric and geriatric medicine are more connected than previously believed.
Caregiver Services: Needs, Benefits, and Best Practices
Authors: Reinhard Susan 
Published: December 2021

Abstract
Just under 1 in 5 Americans (19.2%) are caregivers for adults with chronic illnesses. Caregiving is the great equalizer as caregiving remains an activity that occurs among all generations, racial/ethnic groups, income or educational levels, family types, gender identities, and sexual orientations. This presentation will provide a snapshot of the current status of caregiving in the United States. It will explore why caregiver services are needed and will highlight the impacts many caregivers face as a result of their stepping up to help family and friends. In addition, this presentation will discuss what is considered best practice in caregiver services and how the public and private sectors can work together to develop solutions to support family caregivers and those under their care.
But How Will We Measure It? Co-Creating Assessments of Outcomes in Age-Friendly Care, PA
Authors: Berish Diane 
Published: December 2021

Abstract
Moving from concept to quantitative measurement can be complex. There were several challenges in co-designing measures to assess the impact of Age-Friendly Care, PA, a geriatric workforce enhancement program. First as a FQHC, our clinical partner had not captured the metrics of interest. Second, the co-developed operational definitions for our metrics should be feasible, relevant, and useful for all project members. Third, funder reporting requirements must also be addressed. Working within this context, we co-created 11 outcome indicators structured around the 4Ms (IHI) now with 9 months of data. EMR changes to make data reportable included measuring opioid misuse mitigation, high-risk medication elimination, cognitive assessment and dementia care management, advanced care planning, care partner presence, annual wellness visit completion, pneumonia vaccination rates, colorectal screening rates, mobility goal tracking, and presence of a caregiver. Work continues around formulating themes to create a reportable mechanism for assessing What Matters.
Environmental Gerontology During COVID-19: Aging in Place Since the Pandemic Onset
Authors: Cannon Melissa , Finlay Jessica , Rowles Graham 
Published: December 2021

Abstract
The COVID-19 pandemic is fundamentally changing neighborhood landscapes as we shelter in place and adjust our lifestyles. To age-in-place is to live in one’s home and/or community “safely, independently, and comfortably.” The ability to age-in-place is a public health priority for all, regardless of income or health status, and requires a variety of community resources to be sustainable. Since the pandemic onset, access to neighborhood resources was limited to reduce transmission risks. Changes to economic arrangements and socio-spatial norms have profoundly impacted daily life, though how these influence health and well-being is largely unknown. It is likely that these effects may vary in different communities and contexts; for example, neighborhoods that are able to self-organize to safely provide social support and resources may fare better. This symposium brings together cutting-edge studies in urban and rural U.S. places to explicate how the pandemic is transforming aging-in-place experiences and perspectives. The first presentation shows how rapidly community-based services have adjusted operations to meet the needs of their communities. The second presentation explores strategies to provide social support in rural communities. The third presentation highlights the social health needs of a subset of older adults who had not formed friendships with their neighbors. Together, these studies suggest that close examinations of aging-in-place conditions and mechanisms from organizational, socio-spatial, and social network perspectives are evermore important amid a pandemic. We discuss the implications of these empirical findings in relation to emerging theories within environmental gerontology.
ESPO and Behavioral and Social Sciences Section Symposium: Addressing the Needs of Black, Indigenous, and People of Color (BIPOC) Communities Throughout the Stage Model
Authors: Sprague Briana , Meyer Kylie , Mingo Chivon 
Published: December 2021

Abstract
Behavioral interventions have been successfully deployed to prevent and manage chronic conditions among older persons, improve mental health, and support caregivers’ ability to cope with care stressors. However, intervention effects may not be equally distributed among populations, nor equally acceptable or accessible among Black, Indigenous, and People of Color (BIPOC) communities. In this symposium, we will discuss how behavioral interventions can better meet the needs of BIPOC older adults and caregivers, who may not equally benefit from advancements in behavioral interventions due to issues such as a reliance on non-diverse study samples and lack of cultural tailoring. This symposium will be structured in accordance with the National Institutes of Health Stage Model of Behavioral, and will feature researchers whose work address BIPOC needs across the trajectory of intervention development. Representing Stage 1 research, Fayron Epps, PhD, RN, will describe her use of a community advisory council to develop a faith-based toolkit to support African Americans living with dementia and their caregivers. Next, Laura Gitlin, PhD, MA, will describe her experiences testing a Stage 3 intervention to lower depression among African Americans, including challenges advancing the culturally-tailored program to Stage 4. Lastly, Shanae Rhodes, BSN, RN will describe her Stage 2 evaluation of a conversation group created and attended by women of color to socially connect in response to COVID-19. Although speakers will describe research projects that represent specific research Stages, this symposium will have a large discussion-based component and will cover all parts of the Stage Model of Behavioral Intervention.
Changes in Grandparenting During the Pandemic and Effects on Mental Health: Evidence From England
Authors: Gessa Giorgio Di , Bordone Valeria , Arpino Bruno 
Published: December 2021

Abstract
Policies aiming at reducing rates of hospitalisation and death from Covid-19 encouraged older people to reduce their physical contacts. For grandparents in England, this meant that provision of care for grandchildren was allowed only under very limited circumstances. To date, evidence on changes in grandparenting during the pandemic is scarce and little is known about whether and to what extent reduction in grandchild care provision impacted grandparents’ mental health. Using pre-pandemic data from Wave 9 (2018/19) and the second Covid-19 sub-study (November/December 2020) of the English Longitudinal Study of Ageing, we first described changes in grandparenting since the start of the pandemic. Then, using regression models, we investigated associations between changes in grandparenting and mental health (depression, quality of life, life satisfaction, and anxiety) during the pandemic, while controlling for pre-pandemic levels of the outcome variables. Almost a third of grandparents reported that the amount of grandchild care during the pandemic reduced or stopped altogether, whereas 10% provided as much or more care compared to pre-pandemic levels, mostly to help parents while working. Compared to grandparents who provided grandchild care at some point during the pandemic, those who stopped altogether were more likely to report poorer mental health, even taking into account pre-pandemic health. A reduction in grandparenting was only marginally associated with higher depression. Although policies to limit physical contacts and shield older people reduced their risks of getting ill from Covid-19, our study shows the consequences of stopping childcare provision in terms of poorer mental health among grandparents.