bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extra pituitary midline structural abnormalities associated with ectopic posterior pituitary detected on a new rapid MR protocol (FAST1.2)
Authors: Lyra Arthur , Guimarães Daniel de Faria , Meira Altino Sá , Nunes Arthur Castello Berchielli , Peixoto Guilherme Vieira , Zamot Stella Gallucci , Silva Tatiane Sousa e , Longui Carlos Alberto , Kochi Cristiane , Rocha Antônio José da 
Published: March 2021

Abstract
Background

Ectopic posterior pituitary (EPP) is a malformation of the hypothalamic-pituitary region. Our goal was to describe midline structural brain abnormalities in patients with EPP using a dedicated protocol (FAST1.2 protocol) of magnetic resonance imaging (MRI) to evaluate the hypothalamus and pituitary gland, highlighting their clinical-laboratory correlations.
Methods

A cross-sectional study of patients diagnosed with EPP, and a control group. All individuals were submitted to a dedicated MRI protocol called FAST1.2, which combines the FAST1 protocol developed by our group with 3D T2DRIVE imaging.
Results

We evaluated 36 individuals with EPP and 78 individuals as a control group. One patient had two posterior pituitary lobes, one inside the sella turcica and the other along the pituitary stalk; in five patients, the EPP was along the pituitary stalk; in 28 the EPP was at the infundibular recess of the third ventricle, and in two the EPP was hypothalamic. In the EPP group, eleven individuals had interhypothalamic adhesion (IHA), three septo-optic dysplasia, one a cerebellar malformation, and one a pineal cyst. We did not observe a higher frequency of severe hormonal deficiency or developmental delay in patients with IHA. In the control group, eleven patients had a pineal cyst, three pars intermedia cysts, one hydrocephalus, and one hypothalamic hamartoma.
Conclusion

FAST1.2 acquisition allows confident recognition of regional anatomy and recognition of midline structural abnormalities on T2DRIVE, particularly including the pituitary stalk and IHA, thereby making MRI acquisition faster with no need for intravenous contrast administration. We suggest that IHA could be associated with defects in neuronal migration, as might occur in patients with EPP.
Effects of Different Inflow Rate Patterns and Distributions of Grass Strips on Runoff and Sediment in an Engineering Accumulation Body
Authors: YongCai Lou , ZhaoLiang Gao , Wu Tong , Qi XingYuan 
Published: March 2021

Abstract
Engineering accumulation bodies are critical sources of artificial soil and water loss. The objectives of this study were to evaluate the effects of different inflow rate patterns and distributions of grass strips on runoff and sediment in engineering accumulation bodies. A field runoff plot (20 m long, 1 m wide, and 0.5 m deep) was used for inflow simulation experiments under four inflow rate patterns (even, rising, falling, and rising-falling) and five grass strip patterns (patterns Ⅰ-Ⅴ). The results showed that the changing trends of runoff rate and sediment yield increased with increasing inflow rate and decreased with reduction for the same grass strip pattern. Although the inflow rate pattern affected runoff and sediment yield, it had no significant effect on the total runoff and sediment. The influence of the grass strip pattern on runoff and sediment was significantly higher than that of the inflow rate pattern. The runoff reduction and sediment reduction effects of grass strip patterns were 12.23 to 49.62% and 12.92 to 80.54%, respectively. When grass strips were distributed on a slope in bands (pattern Ⅴ), the soil and water conservation effects were ideal, reducing the average runoff and sediment by 44.98% and 58.09%, respectively. Sediment reduction caused by decreasing runoff (SRR) was the main factor controlling erosion and sediment yield. This study can guide the configuration of vegetation control measures for soil and water loss in engineering accumulation bodies.
Long-Term Joint Operation of Cascade Reservoirs Using Enhanced Progressive Optimality Algorithm and Dynamic Programming Hybrid Approach
Authors: Chen Jia 
Published: March 2021

Abstract
Dynamic programming (DP) is one of the most classical methods adopted for reservoir operation. It reduces the computational efforts of complex high-dimensional problems by piecewise dimensionality reduction and provides the global optimums of the problems, but it suffers the “curse of dimensionality”. Progressive optimality algorithm (POA) has been used repeatedly in reservoir operation studies during last decades because it alleviates the “curse of dimensionality” of DP and has good convergence and extensive applicability. Nonetheless, POA encounters two difficulties in multi-reservoir operation applications. One is the transfer interrupt problem that makes the search procedure hard to achieve free allocation of water between two nonadjacent stages, and the latter is the dimensionality problem that leads to a low convergence rate. In order to overcome these deficiencies, this paper makes some enhancements to POA and proposes a hybrid approach combining the enhanced POA and DP (EPOA-DP) for long-term operation of cascade reservoir systems. In EPOA-DP, EPOA is employed to improve the quality of the solutions and DP is used to reduce the computational effort of the two-stage problem solution. The proposed approach was tested using a real world four-reservoir cascade system and a ten-reservoir benchmark test example, and the results demonstrate that it outperforms POA both in computational time and quality of the solution.
&nbsp;A Multi-Layered LSTM for Predicting Physician Stress During an ED Shift
Authors: Prabhu Vishnunarayan Girishan , Taaffe Kevin , Pirrallo Ronald 
Published: March 2021

Abstract
Emergency Department (ED) physicians are faced with complex care settings, including a high level of uncertainty and intensity. Burnout among physicians is increasing every year, and ED physicians are one of the groups most prone to burnouts and work-related stress in the US. This research focused on developing a supervised Long Short-Term Memory (LSTM) artificial neural network model to predict a physician’s stress level based on their physiological data. Twelve attending physicians working a 3:00 pm - 11:00 pm shift at Greenville Memorial Hospital (GMH) in Greenville, SC, participated in the study. Stress levels were estimated using physiological measures, including heart rate and electrodermal activity. Over 100 hours of physiological data were collected from 12 eight-hour shifts. Initially, an 80:20 split was used on the 12 individual datasets for training and testing the model. Further, to develop a generalizable model, the data were merged, and a 60:20:20 split was used for training, validating, and testing the model. On the test set, the model achieved values of 0.98, 0.17, and 0.005 as the R-squared, RMSE, and loss for EDA data and 0.99, 0.41, and 0.002 for HR data.
An overview of technologies and devices against COVID-19 pandemic diffusion: virus detection and monitoring solutions
Authors: de Fazio R. , Sponziello A. , Cafagna D. , Velazquez R. , Visconti P. 
Published: March 2021

Abstract
The year 2020 will remain in the history for the diffusion of the COVID-19 virus, originating a pandemic on a world scale with over a million deaths. From the onset of the pandemic, the scientific community has made numerous efforts to design systems to detect the infected subjects in ever-faster times, allowing both to intervene on them, to avoid dangerous complications, and to contain the pandemic spreading. In this paper, we present an overview of different innovative technologies and devices fielded against the SARS-CoV-2 virus. The various technologies applicable to the rapid and reliable detection of the COVID-19 virus have been explored. Specifically, several magnetic, electrochemical, and plasmonic biosensors have been proposed in the scientific literature, as an alternative to nucleic acid-based real-time reverse transcription Polymerase Chain Reaction (PCR) (RT-qPCR) assays, overcoming the limitations featuring this typology of tests (the need for expensive instruments and reagents, as well as of specialized staff, and their reliability). Furthermore, we investigated the IoT solutions and devices, reported on the market and in the scientific literature, to contain the pandemic spreading, by avoiding the contagion, acquiring the parameters of suspected users, and monitoring them during the quarantine period.
A Review: Synthesis and Pharmacological Profile of [1, 5]-Benzothiazepine
Authors: Khasimbi Shaik , Ali Faraat , Neha Kumari , Wakode Sharad , Chauhan Garima 
Published: March 2021

:
The 1, 5-benzothiazepine derivatives are of particular interest for lead discovery since they have been found active against different families of targets.1,5-Benzothaizepines representatives of benzologs of 1,4-thiazepine and one of the three possible benzo-condensed derivatives, i.e. the 1,5-benzothiazepines are useful compounds in the drug research which has stimulated the invention of a wide range of synthetic methods for their preparation and chemical transformations. 1,5-Benzothiazepine and its derivatives exhibit diverse biological activities such as tranquilizer, antidepressant, antihypertensive, calcium channel blocker, antimicrobial, anticancer, antifungal, anthelmintic, anti-diabetic, amyloid imagining agents and anticancer agents. This review also discusses the structure-activity relationship of the most potent compounds. It can act as an important tool for medicinal chemists to develop newer compounds possessing 1, 5-benzothiazepines moiety that could be better agents in terms of efficacy and safety.
Computing Analysis of Degree and Connection Based Irregular Indices of Polycyclic Aromatic Hydrocarbons
Authors: Javaid Muhammad , Ibraheem Muhammad , Raheem Abdul 
Published: March 2021

Introduction:
A graph is supposed to be regular if all vertices have equal degree, otherwise irregular.

Materials and Methods:
Polycyclic aromatic hydrocarbons are important combusting material and considered as
a class of carcinogens. These polycyclic aromatic hydrocarbons play an important role in graphitisation of medical
science. A topological index is a function that assigns a numerical value to a (molecular) graph that predicts
various physical, chemical, biological, thermodynamical and structural properties of (molecular) graphs. An irregular
index is a topological index that measures the irregularity of atoms with respect to their bonding for the
chemical compounds which are involved in the under studying graphs.

Results and Discussion:
In this paper, we will compute an analysis of distance based irregular indices of polycyclic
aromatic hydrocarbons. A comparison among the obtained indices with the help of their numerical values
and the 3D presentations is also included. The efficient and steady indices of polycyclic aromatic hydrocarbons
are addressed in the form of their irregularities.

Conclusion:
Connection based study of the molecular graphs is more suitable than the degree based irregularity
indices.
Plasmonic and Hybrid Whispering Gallery Mode–Based Biosensors: Literature Review
Authors: Manzo Maurizio , Cavazos Omar , Huang Zhenhua , Cai Liping 
Published: March 2021

Background
The term “plasmonic” describes the relationship between electromagnetic fields and metallic nanostructures. Plasmon-based sensors have been used innovatively to accomplish different biomedical tasks, including detection of cancer. Plasmonic sensors also have been used in biochip applications and biosensors and have the potential to be implemented as implantable point-of-care devices. Many devices and methods discussed in the literature are based on surface plasmon resonance (SPR) and localized SPR (LSPR). However, the mathematical background can be overwhelming for researchers at times.

Objective
This review article discusses the theory of SPR, simplifying the underlying physics and bypassing many equations of SPR and LSPR. Moreover, we introduce and discuss the hybrid whispering gallery mode (WGM) sensing theory and its applications.

Methods
A literature search in ScienceDirect was performed using keywords such as “surface plasmon resonance,” “localized plasmon resonance,” and “whispering gallery mode/plasmonic.” The search results retrieved many articles, among which we selected only those that presented a simple explanation of the SPR phenomena with prominent biomedical examples.

Results
SPR, LSPR, tilted fiber Bragg grating, and hybrid WGM phenomena were explained and examples on biosensing applications were provided.

Conclusions
This minireview presents an overview of biosensor applications in the field of biomedicine and is intended for researchers interested in starting to work in this field. The review presents the fundamental notions of plasmonic sensors and hybrid WGM sensors, thereby allowing one to get familiar with the terminology and underlying complex formulations of linear and nonlinear optics.
As dinâmicas de poder na apropriação dos recursos hídricos: estudo de caso da bacia hidrográfica do rio Urussanga, SC
Authors: Virtuoso José Carlos , Carlyle Torres Bezerra de Menezes Carlyle Torres Bezerra de Menezes , Viviane Kraieski de Assunção Viviane Kraieski de Assunção 
Published: March 2021

Vivemos um contexto de estresse hídrico decorrente do modelo econômico hegemônico responsável por uma crise ambiental planetária sem precedentes, que vem causando a devastação dos ecossistemas e o desequilíbrio ecológico. Tal quadro pode ser constatado na Bacia Hidrográfica do rio Urussanga, Sul de Santa Catarina, onde atividades econômicas, como a mineração de carvão, promoveram severa degradação ambiental, contaminando solo, água e ar. Trata-se da bacia catarinense de menor área, porém com passivos ambientais ainda sem intervenção. Diante desse cenário, o presente trabalho buscou analisar as dinâmicas de poder determinantes na apropriação dos recursos hídricos nesse território. Para tanto, realizou-se pesquisa de abordagem qualitativa, nas modalidades bibliográfica, documental, de campo e estudo de caso, utilizando-se instrumento de análise com enfoque na apropriação de recursos comuns. Como resultados, constatou-se sobreposição de poder do setor econômico em relação ao interesse coletivo, como na gestão da água, cuja atuação de um setor alinha-se aos segmentos políticos, identificando-se fatores que evidenciam assimetria nos espaços de tomada de decisão. Nesse contexto, o carbonífero se destaca, utilizando estratégias como financiamento de campanhas políticas para se manter, mesmo diante de indicadores de insustentabilidade. Concomitantemente, os instrumentos legais de tutela da água mostram-se insuficientes para evitar a sua poluição.
Proposed Business Strategy for XYZ Consultant Company to Financial Improvement Through Acquisition Strategy
Authors: Fitriani Novi , Koesrindartoto Deddy Priatmodjo 
Published: March 2021

XYZ is a university with the best reputation in Indonesia which has 12 companies engaged in consulting services (construction and non-construction)). The proportion of ownership in this business varies from 20% to 99.99%. This business has several companies that are inefficient and unhealthy because operating costs are greater than revenue. In addition, in 2019, this consulting company experienced a decrease in revenue by 7.11% while the cost of goods sold increased by 7.45%. This study aims to select which companies have good and healthy performance, create new and effective business strategies for the best performing companies, and develop sustainable business and new competitive advantages. This research methodology is qualitative using secondary data in the form of annual financial reports from 12 companies for 2015-2019, websites and other information media. External analysis in this study using macroeconomics, PEST, Porter's Five Forces, and Benchmark Analysis. While the internal analysis uses Financial Ratio Analysis and Altman-Z Score. The tools used to obtain business solutions and strategies from the XYZ consulting firm case are Business Level Formulations, Business Level Strategies, Functional Strategies, and Implementation Strategies. One of the strategies that the author applies in this case is by implementing an acquisition strategy
After analyzing and calculating using the Financial Ratio and Altman-Z Score of 12 companies, the result shows that there are only 7 companies that have good and healthy performance so that they are included in the "safe zone" category with a discriminant zone Z> 2.99. The acquisition strategy was created by combining these companies. The first step is to evaluate each company, then calculate the acquisition to find out the synergy value of the acquisition to compare the value when the acquisition was made and what was not. The calculation results show that the company's FCFF accumulation after the next 10 years on 2030, In the event of an acquisition is IDR 124,131,871,981.11. Meanwhile, if there is no acquisition is IDR 117,285,044,723.00. So that we know there have added value of the synergy IDR 6,846,827,258.11.
Epidemiological Profile of Diabetes Mellitus Patients in Diabetes Center in King Salman Specialist Hospital Hail Region Saudi Arabia
Authors: Al-Shammari Waffa Aswaq , Al-Ateeq Mosa , Al-Shubrami Suad , Al- Jabreen Abdullah , Al-Shammari Mona , Al-Jasir Mashael 
Published: March 2021

Objective: To investigate the degree of association between the specific epidemiologic factors of diabetes in the Hail Region of Saudi Arabia.
Methodology: The research is considered a case study using information from the King Salman Specialist Hospital in Hail Saudi Arabia. 5000 Medical reports and records were used in the retrospective cross-sectional study. Data analysis was done using SPSS statistical software.
Results: The Chi-square results indicated an insignificant association between gender and follow-up status (P > 0.05). Both males and females sought treatment equally, whether follow-up or new treatments (P > 0.05). There was a significant association between gender and diabetes type.
The t-test results had varied results for the differences in age, BMI, and diabetes treatment. Age differences had no significant impact on the prevalence of diabetes among males and females (t (4998) = -0.63, P > 0.05. Men had lower glycohemoglobin levels (8.11) differed significantly from that of women (8.58) t (4786) = -10.62, p < 0.05. also, the creatine levels were higher in females than males. There were significant differences in low-density lipoprotein, hemoglobin, and BMI between men and women.
Conclusions: The findings indicated differences in treatment such as unawareness of insulin injection, ignorance of health practices and unhealthy dietary habits, gender-related disparities, the inheritance of genes through which the disorder manifests, and exposure to environmental factors triggering and exacerbating the condition. Future studies should consider the genetic dimension Diabetes.
Servicio doméstico y desigualdades en Santiago del Estero
Authors: Torres Lucas Emanuel 
Published: March 2021

Con el presente informe me propongo socializar mi tesis doctoral defendida en marzo del año 2019 en el marco del Doctorado en Estudios Sociales de América Latina del Centro de Estudios Avanzados de la Universidad Nacional de Córdoba. Presento una síntesis de los principales componentes de la investigación, con el fin de contribuir a la comunidad de las Ciencias Sociales y al colectivo de trabajadoras del servicio doméstico, visibilizando las particularidades de la actividad en una provincia del norte argentino. La estructura sigue la lógica de la tesis, comenzando por el planteo del problema, seguido por el marco teórico-metodológico que permitió abordar el objeto de estudio, los principales resultados, analizados desde un abordaje cuantitativo y cualitativo, y las reflexiones finales.
Se observan múltiples desigualdades hacia el interior del mercado de trabajo santiagueño, con altas tasas de informalidad y precariedad, sumado a las inequidades de género. El servicio doméstico se presenta como la principal actividad entre las mujeres que trabajan, constituido principalmente por trabajadoras provenientes de sectores populares urbanos, cuyas trayectorias laborales son intermitentes e inestables. Las relaciones al interior de la actividad giran en torno a la autoridad de las familias empleadoras, quienes determinan unilateralmente las condiciones de trabajo.
Discapacidad y distribución de bienes simbólicos
Authors: Rapanelli Antonella 
Published: March 2021

Este artículo constituye un análisis de la experiencia institucionales de estudiantes con discapacidad en dos universidades del conurbano bonaerense, la Universidad Nacional de Quilmes (UNQ) y la Universidad Nacional Arturo Jauretche (UNAJ). El objetivo de este texto es comprender las dinámicas internas de las instituciones y su relación con la distribución de bienes simbólicos. Las dimensiones de análisis emergentes de la experiencia de investigación situaron la reflexión en los procesos de identificación, la construcción de la ciudadanía universitaria, el fenómeno de vecinalización de las universidades del Conurbano y las experiencias en la política estudiantil.
El foco de este trabajo está puesto en algunas dimensiones culturales y simbólicas que son condicionantes de la experiencia de la discapacidad en el ámbito universitario. Estas reflexiones permiten entender que la construcción de una universidad accesible implica una transformación cultural más amplia que modifique el sentido común que se construye alrededor de la discapacidad en nuestra sociedad.
Revealed Comparative Advantage Method for Solving Multicriteria Decision-making Problems
Authors: Gogodze Joseph 
Published: March 2021

Abstract
This study proposes and analyzes a new method for the post-Pareto analysis of multicriteria decision-making (MCDM) problems: the revealed comparative advantage (RCA) assessment method. An interesting feature of the suggested method is that it uses the solution to a special eigenvalue problem and can be considered an analog/modification in the MCDM context of well-known ranking methods including the authority-hub method, PageRank method, and so on, which have been successfully applied to such fields as economics, bibliometrics, web search design, and so on. For illustrative purposes, this study discusses a particular MCDM problem to demonstrate the practicality of the method. The theoretical considerations and conducted calculations reveal that the RCA assessment method is self-consistent and easily implementable. Moreover, comparisons with well-known tools of an MCDM analysis shows that the results obtained using this method are appropriate and competitive. An important particularity of the RCA assessment method is that it can be useful for decision-makers in the case in which no decision-making authority is available or when the relative importance of various criteria has not been preliminarily evaluated.