bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pyroxenite-hosted chalcopyrites from Sung Valley, Meghalaya, NE India: implications for the formation of both high- and low-temperature sulfides in plume-derived magma
Authors: Choudhary Shubham , Sen Koushik , Kumar Santosh 
Published: May 2021

Abstract

Sulfides play a crucial role in the distribution of chalcophile elements in the Earth's mantle. In this work, combined petrography and mineral chemistry of sulfide and diopside in a pyroxenite from an ultramafic–alkaline–carbonatite complex of NE India, related to the Kerguelen plume, was carried out and a considerably high sulfur concentration in the parental melt of the pyroxenite was obtained. Two types of sulfide, with similar compositions, were detected in pyroxenite: Type A are multifaceted polygons, elliptical and spherical in shape, occurring as poikilitic inclusions in diopside; and Type B are intergranular sulfides of irregular shapes in silicate grains. These sulfides are often partially replaced by magnetite. Mineral chemistry suggests that both types of sulfide are products of re-equilibration of high-temperature monosulfide solid solution and represent a low-temperature (
c.
400°C) mineral phase of the Cu–Fe–S system. Petrographical features suggest that the sulfides were separated as immiscible melt droplets at the time of sulfur saturation and fractionation of diopside in the coexisting silicate magma. Our study implicates that both high- and low-temperature sulfides can form in the plume-associated ultramafic rocks.
Mineral systems and their putative link with mantle plumes
Authors: Pirajno Franco 
Published: May 2021

Abstract
In this contribution, I discuss the putative link of mantle plumes with selected categories of mineral systems. Continental rifting and break-ups can be induced by the upwelling of mantle plumes, also resulting in the generation of a wide range of mineral deposits. These include magma-associated ores, anorogenic igneous events responsible for iron oxide–copper–gold (IOCG) deposits, carbonatites and hydrothermal-induced mineralization, as well as hydrocarbons, salt domes, petroleum and gas, and several mineral systems in continental passive margins. Amongst the magma-associated mineral systems, the Ni–Cu–platinum group element (PGE), Fe–Ti–V and Cr deposits are the economically most important, such as those of the Bushveld Igneous Complex in South Africa. Anorogenic magmas are generally alkaline and associated with IOCG mineral systems, as exemplified by the giant Olympic Dam and similar deposits in South America. Carbonatites are considered as a distal effect of hotspot mantle plumes, as shown by Mount Weld in Australia, which may be related to the Bushveld Superplume. Plume-related thermal anomalies are the principal factor for the inception of hydrothermal circulation and the genesis of a wide range of hydrothermal mineral systems in rift-related tectonic settings. These include large-scale sedimentary-rock-hosted metalliferous ores, such as sedimentary exhalative (SEDEX) deposits. A modern example of is provided by the Red Sea brine pools. Some key examples are presented in this paper.
Efficiency and Clinical Outcomes of Moses Technology with Flexible Ureteroscopic Laser Lithotripsy for Treatment of Renal Calculus
Authors: Wang Mingqing , Shao Qiang , Zhu Xiaodong , Wang Zhiqian , Zheng An 
Published: May 2021

<b><i>Objective:</i></b> The aim of the study was to compare the efficiency and clinical outcomes of Moses contact mode (MCM) and regular dusting mode (RDM) during flexible ureteroscopic lithotripsy (FURL) for treatment of renal calculus. <b><i>Methods:</i></b> This retrospective analysis examined 216 patients with renal calculus who underwent FURL with MCM or RDM between March 2015 and January 2020. Stone characteristics, including size, volume, and density, were collected. Laser parameters, including laser type, laser working time, laser pause time, and foot-pedal use, were automatically recorded by the lithotripter work panel. The percentages of laser working time and laser pause time, stone fragmentation efficiency (SFE; volume/laser working time), postoperative complications, including fever and acute renal failure (ARF), stone-free rate (SFR), and the need for auxiliary procedures were determined. <b><i>Results:</i></b> There were no significant differences in preoperative demographic and stone characteristics between the MCM group and the RDM group. The MCM group had a shorter laser working time (4.99 ± 1.06 vs. 5.94 ± 0.96 min, <i>p</i> &#x3c; 0.001) and a greater SFE (137.86 [163.78–114.38] versus 114.94 [132.06–101.34] mm<sup>3</sup>/min, <i>p</i> &#x3c; 0.001), which shortened the overall operative time (18.39 ± 5.13 vs. 21.17 ± 6.78 min, <i>p</i> = 0.001). There were no differences in postoperative complications, including fever and ARF, SFR (86.8 vs. 85.3%, <i>p</i> = 0.743), and auxiliary procedures between the 2 groups. <b><i>Conclusions:</i></b> Using Moses laser technology with FURL significantly reduced laser working time and increased SFE, which shortened overall operative time. Urologists should consider this new instrument for the clinical management of renal calculus.
Composite Metric for Benchmarking Site Performance in Transcatheter Aortic Valve Replacement: Results From the STS/ACC TVT Registry
Authors: Desai Nimesh D. , O’Brien Sean M. , Cohen David J. , Carroll John , Vemulapalli Sreekanth , Arnold Suzanne V. , Forrest John K. , Thourani Vinod H. , Kirtane Ajay J. , O’Neil Brian , Manandhar Pratik , Shahian David M. , Badhwar Vinay , Bavaria Joseph E. 
Published: May 2021

Background:
Transcatheter aortic valve replacement (TAVR) is a transformative therapy for aortic stenosis. Despite rapid improvements in technology and techniques, serious complications remain relatively common and are not well described by single outcome measures. The purpose of this study was to determine whether there is site-level variation in TAVR outcomes in the United States using a novel 30-day composite measure.

Methods:
We performed a retrospective cohort study using data from the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapies Registry to develop a novel ranked composite performance measure that incorporates mortality and serious complications. The selection and rank order of the complications for the composite was determined by their adjusted association with 1-year outcomes. Sites with risk-adjusted outcomes significantly more or less frequent than the national average based on a 95% probability interval were classified as performing worse or better than expected.

Results:
The development cohort consisted of 52 561 patients who underwent TAVR between January 1, 2015, and December 31, 2017. Based on associations with 1-year risk-adjusted mortality and health status, we identified 4 periprocedural complications to include in the composite risk model in addition to mortality. Ranked empirically according to severity, these included stroke, major, life-threatening or disabling bleeding, stage III acute kidney injury, and moderate or severe perivalvular regurgitation. Based on these ranked outcomes, we found that there was significant site-level variation in quality of care in TAVR in the United States. Overall, better than expected site performance was observed in 25/301 (8%) sites, performance as expected was observed in 242/301 sites (80%), and worse than expected performance was observed in 34/301 (11%) sites. Thirty-day mortality; stroke; major, life-threatening, or disabling bleeding; and moderate or severe perivalvular leak were each substantially more common in sites with worse than expected performance as compared with other sites. There was good aggregate reliability of the model.

Conclusions:
There are substantial variations in the quality of TAVR care received in the United States and 11% of sites were identified as providing care below the average level of performance. Further study is necessary to determine structural, process-related, and technical factors associated with high- and low-performing sites.
Iterative Paraphrastic Augmentation with Discriminative Span Alignment
Authors: Culkin Ryan , Hu J. Edward , Stengel-Eskin Elias , Qin Guanghui , Durme Benjamin Van 
Published: May 2021

AbstractWe introduce a novel paraphrastic augmentation strategy based on sentence-level lexically constrained paraphrasing and discriminative span alignment. Our approach allows for the large-scale expansion of existing datasets or the rapid creation of new datasets using a small, manually produced seed corpus. We demonstrate our approach with experiments on the Berkeley FrameNet Project, a large-scale language understanding effort spanning more than two decades of human labor. With four days of training data collection for a span alignment model and one day of parallel compute, we automatically generate and release to the community 495,300 unique (Frame,Trigger) pairs in diverse sentential contexts, a roughly 50-fold expansion atop FrameNet v1.7. The resulting dataset is intrinsically and extrinsically evaluated in detail, showing positive results on a downstream task.
Preliminary observations on terrestrial isopods (Peracarida, Isopoda) in the transitional coastal desert of Chile (24-29°S)
Authors: De los Ríos-Escalante Patricio , Pizarro-Araya Jaime , Alfaro Fermín M. , Perez-Schultheiss Jorge 
Published: May 2021

Abstract
The terrestrial isopods of Chile make a group on which until now only a few studies have been done, most of which based mainly on species records in isolated zones. The aim of the present study was to make an attempt at characterization of the isopods present in three coastal protected areas in the Atacama Desert and northern-central Chile, and compare the results with literature records for northern and central Chile. The collected specimens belong to the genus Benthanoides (Oniscoidea, Philosciidae), probably to the species Benthanoides pauper that was originally described for central Chile. The obtained results would not agree with literature records that described the presence of two species of the genus Tylos (Oniscoidea, Tylidae) between 26-29°S, and it would be the first isopod genus recorded north of 26°S (Paposo priority site, Antofagasta Region). More systematic and ecological studies would be necessary for understanding the geographical distribution of Chilean terrestrial isopods.
Biological traits of the spot prawn Pandalus platyceros Brandt, 1851 (Decapoda, Caridea) at its southernmost distribution limit
Authors: Ortega-Lizárraga Gilberto G. , Pérez-González Raúl , Rodríguez-Domínguez Guillermo , Aragón-Noriega E. Alberto , Mendivil-Mendoza Jaime E. , Franco-Ruíz Jesús A. 
Published: May 2021

Abstract
The spot prawn fishery, targeting Pandalus platyceros, has failed to prove commercially viable on the Mexican Pacific coast. A survey was carried out off the northwestern coast of Baja California, at depths of 140-180 m. The objective was to describe the biological traits of the species to test the hypothesis that warmer water stimulates higher growth parameters. An average model was estimated that anticipated an inverted exponential growth curve, consequently the growth parameters of the Von Bertalanffy model were obtained as , carapace length (CL) and . Being a protandric hermaphrodite, the transition size was estimated at 40.8 mm CL. The results challenged the hypothesis that P. platyceros grows faster in temperate environments than in cold environments.
Life cycle and connectivity of the spiny lobster, Panulirus spp.: case studies from Brazil and the Wider Caribbean (Decapoda, Achelata)
Authors: Cruz Raúl , Borda Carlos A. , Santana João V. M. , Barreto Carlos G. , Paiva Bárbara P. , Gaeta Juliana C. , Torres Marina T. , Da Silva Jessica L. S. , Cintra Israel H. A. 
Published: May 2021

Abstract
In this study, we look at recent developments in our understanding of the life cycle of the red spiny lobster Panulirus argus (Latreille, 1804) and examine the evidence for connectivity between geographical regions, especially the north-northeast Brazilian continental shelf and the Wider Caribbean. The study also covers aspects of reproduction, phyllosoma density, large-scale oceanic circulation, self-recruitment, settlement patterns, ecological behaviour, and the impact of the Amazon and Orinoco river discharge on recruitment. Our findings support the hypothesis that lobster larvae are transported by ocean currents and free eddies from Brazil to the Caribbean via the Lesser Antilles, outlining a south-to-north connectivity. In addition, we look into the probable existence of hybrids between sympatric lobster species, as evidenced by differences in colour patterns and morphology.
A New Source for the Study of Avicenna’s Safavid Reception
Authors: Di Vincenzo Silvia 
Published: May 2021

Abstract
MS Cambridge, University Library, Or. 658 is a collection of eleven texts transmitted in anonymous and untitled form whose precise content has to date remained obscure. On closer inspection, however, the manuscript turns out to be a so-far neglected witness of some authentic and pseudepigraph works of, among others, Avicenna (d. 427/1037) and Mullā Ṣadrā (d. 1050/1640–1641). This paper aims to provide an identification of all the works contained therein, along with a hypothetical reconstruction of the milieu in which the codex was produced.
Egyptian Arabic Proverbs in the Cairo Genizah
Authors: Ahmed Mohamed A.H. 
Published: May 2021

Abstract
The Cairo Genizah is a fundamental source for the study of Jewish History and culture in Medieval and pre-modern times. Moreover, the importance of the Cairo Genizah to Arabic studies should not be underestimated. This article investigates a previously unpublished fragment that features a selection of Egyptian Arabic proverbs written in Hebrew script, i.e. Judaeo-Arabic, which have been kept for centuries in the Cairo Genizah and that, to date, have not been found in other sources of Egyptian proverbs.
COVID-19 Pandemic and Rescue of Pets. The Role of Veterinarians in the Human-Animal-Environment Relationship at the Time of the Coronavirus
Authors: Adamelli Serena , Tocchio Antonio , Brini Carlo 
Published: May 2021

Abstract
Adequate training and collaboration skills for all the professional figures involved in animal rescue activities are needed. Nowadays the real challenge for all rescuers is to consider the multiple aspects of the human-animal-environment relationship that have changed profoundly throughout history and that make the COVID-19 pandemic unique in its kind. In this period the emergency to be addressed consists in providing the assistance of animals which belong to people who have died, been hospitalized or forced to isolate. A careful analysis of the different scenarios reveals that there is no single solution to intervene, but that it is necessary to find the most suitable alternative to individual cases. The aim of this paper is to offer specific indications to volunteers, veterinarians and not, in different scenarios not losing sight of the goal: to protect the welfare of the animal and its owner, avoiding the spread of the infection.
National Turbulence and the Turbos of the World Cinema System
Authors: Andrew Dudley 
Published: May 2021

Abstract
From the outset cinema was metropolitan. Producers needed access to financing, pools of talent, specialized equipment, and laboratories that one could only find in urban centers. In certain cinema-cities (Berlin, Paris, Buenos Aires, Mumbai, Taipei, etc.) reside ambitious writers, producers, and filmmakers who were driven to outdo, or modify, or simply copy what they saw, employing their own culture’s raw material. Thus, the Jameson-Moretti law applies: local content, pertinent to each nation, was poured into forms that were adopted, with strategic alterations, from Hollywood. Where are today’s hotspots? Where does cinema seem crucial and talked about?
Let’s abandon the map (where necessarily one region stands front and center), and instead let’s spin the globe. As it whirls, our eye intermittently catches glimpses of the shapes of the most sizeable nations. Today China and Nigeria stand out prominently alongside India and Russia. So dense are they with film activity that the globe is distended and wobbles out of true. Only sixty years ago China and Nigeria were places that had no place in World Cinema; they gained recognition only when a few promising art films found their way to the European festivals that served as image exchange centers. Today that promise has been fulfilled beyond, indeed against, expectations. Recapitulating Hollywood in its heyday Nollywood and China (Beijing/Shanghai/Qingdao) have become thoroughly corporate and market-savvy, turning out standardized and predictable products. If fresh images are to renew World Cinema, it will hardly be from the urban image-centers. On our globalized globe, novelty should be sought on the periphery of these former peripheral nations. And indeed, exciting new work has been bubbling beyond the dense cultural centers of these nations. Independent art films and documentaries have emerged from dark corners of both places thanks to the network of festivals around the globe, but increasingly and paradoxically thanks to the rival medium of the internet, with its networks of informal distribution and what used to be called “word of mouth.”
A CLIMATOLOGY BASED FORECAST TOOL FOR COASTAL FLOODING IN THE LOWCOUNTRY
Authors: Coz Joseph , Alsheimer Frank , Lindner Bernhard Lee 
Published: May 2021

AbstractCoastal nuisance flooding has increased by an order of magnitude over the past half century, but the National Weather Service has a limited suite of statistical tools to forecast them. Such a tool was developed using coastal flood events from 1996—2014 in Charleston, South Carolina, which were identified and classified by prevailing synoptic conditions based on composite mean sea level pressure anomalies. The synoptic climatology indicated low level northeasterly winds dominated the forcing in anticyclonic and cyclonic events, while a southeasterly surge was the main forcing component for frontal events. Tidal anomalies between flood events and previous low tides were used to create linear regression models for each composite classification studied for forecasting levels of coastal flood magnitude. Beta tests using data from 2018—2019 confirmed the effectiveness of the models with RMSE values less than 0.3 ft and MAE values less than 0.25 ft for each event type. The veracity of the methods was further verified by a multiple day case study from November 2018, where the model was tested against both statistically predicted heights and heights based on ETSS Model (v2.2). The RMSE and MAE for the statical model were 0.18 and 0.15 respectively, while the same values for the ETSS model were 0.28 and 0.23 respectively.
Establishing a high-precision ZHD model of China using 8 years of radiosonde data
Authors: Pengfei Xia , Shirong Ye , Caijun Xu , Weiping Jiang 
Published: May 2021

AbstractTropospheric hydrostatic delay is one of the major source of errors in Global Navigation Satellite System (GNSS) navigation and positioning, and an important parameter in GNSS meteorology. This work first proposes a new method of computing zenith hydrostatic delay (ZHD) based on precipitable water vapor (PWV), using radiosonde data. Next, using these calculations as a reference, the performance of three empirical ZHD models and three ZHD integral models in China is assessed using benchmark values obtained from 8 years (2010-2017) of radiosonde data recorded at 75 stations across China. Finally, we provide a new revised ZHD model that can be applied to China and validate its performance using radiosonde data collected in China in 2018. The statistical results indicate that the ZHD can be estimated by this new model with an accuracy of several millimeters. Due to its performance and simplicity, this new model is shown to be the optimal ZHD model for use in China.
Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options
Authors: Malcikova Jitka , Pavlova Sarka , Kunt Vonkova Barbara , Radova Lenka , Plevova Karla , Kotaskova Jana , Pal Karol , Dvorackova Barbara , Zenatova Marcela , Hynst Jakub , Ondrouskova Eva , Panovska Anna , Brychtova Yvona , Zavacka Kristyna , Tichy Boris , Tom Nikola , Mayer Jiri , Doubek Michael , Pospisilova Sarka 
Published: May 2021

Abstract
Patients with chronic lymphocytic leukemia (CLL) bearing TP53 mutations experience chemorefractory disease and are therefore candidates for targeted therapy. However, the significance of low-burden TP53 mutations with &lt;10% variant allele frequency (VAF) remains a matter for debate. Herein, we describe clonal evolution scenarios of low-burden TP53 mutations, the clinical impact of which we analyzed in a “real-world” CLL cohort. TP53 status was assessed by targeted next-generation sequencing (NGS) in 511 patients entering first-line treatment with chemo- and/or immunotherapy and 159 patients in relapse before treatment with targeted agents. Within the pretherapy cohort, 16% of patients carried low-burden TP53 mutations (0.1% to 10% VAF). Although their presence did not significantly shorten event-free survival after first-line therapy, it affected overall survival (OS). In a subgroup with TP53 mutations of 1% to 10% VAF, the impact on OS was observed only in patients with unmutated IGHV who had not received targeted therapy, as patients benefited from switching to targeted agents, regardless of initial TP53 mutational status. Analysis of the clonal evolution of low-burden TP53 mutations showed that the highest expansion rates were associated with fludarabine, cyclophosphamide, and rituximab regimen in both first- and second-line treatments (median VAF increase, 14.8× and 11.8×, respectively) in contrast to treatment with less intense treatment regimens (1.6×) and no treatment (0.8×). In the relapse cohort, 33% of patients carried low-burden TP53 mutations, which did not expand significantly upon targeted treatment (median VAF change, 1×). Sporadic cases of TP53 mutations' clonal shifts were connected with the development of resistance-associated mutations. Altogether, our data support the incorporation of low-burden TP53 variants in clinical decision making.
BCORgene alterations in hematologic diseases
Authors: Sportoletti Paolo , Sorcini Daniele , Falini Brunangelo 
Published: May 2021

AbstractThe BCL6 corepressor (BCOR) is a transcription factor involved in the control of embryogenesis, mesenchymal stem cells function, hematopoiesis, and lymphoid development. Recurrent somatic clonal mutations of the BCOR gene and its homolog BCORL1 have been detected in several hematologic malignancies and aplastic anemia. They are scattered across the whole gene length and mostly represent frameshifts (deletions, insertions), nonsense, and missence mutations. These disruptive events lead to the loss of full-length BCOR protein and to the lack or low expression of a truncated form of the protein, both consistent with the tumor suppressor role of BCOR.BCOR and BCORL1 mutations are similar to those causing 2 rare X-linked diseases: oculofaciocardiodental (OFCD) and Shukla-Vernon syndromes, respectively. Here, we focus on the structure and function of normal BCOR and BCORL1 in normal hematopoietic and lymphoid tissues and review the frequency and clinical significance of the mutations of these genes in malignant and nonmalignant hematologic diseases. Moreover, we discuss the importance of mouse models to better understand the role of Bcor loss, alone and combined with alterations of other genes (eg, Dnmt3a and Tet2), in promoting hematologic malignancies and in providing a useful platform for the development of new targeted therapies.