bluuebunny/crossref_metadata_2025_split huggingface dataset:
MICE Tourism (Meetings, Incentives, Conferencing and Exhibitions) como gerador de Turismo Interno: Analisando a cidade de Pelotas, RS
Authors: Fumi Chim-Miki Adriana , Dos Santos Júnior Adalberto , Oliveira Matos Christina 
Published: November 2021

Este artigo objetiva apresentar as oportunidades do Turismo MICE Interno para as cidades consideradas regionais. Esta modalidade de turismo urbano, em termos mundiais e nacionais tem apresentado expressivo crescimento. Além disso, está sendo indicada como um produto complementar ou substituto ao clássico turismo de Sol e Praia, especialmente para destinos que estão apresentando sintomas da maturidade deste modelo, ou áreas em que não há condições naturais favoráveis a um completo desenvolvimento baseado em Sol e Praia. Objetivando contribuir com a literatura acadêmica, se apresenta uma revisão conceitual e tipológica do turismo MICE, seguido de uma revisão de determinantes ou atributos para destinos MICE. Desta revisão se extrai os principais determinantes da competitividade do turismo MICE regional, aplicando-os em uma análise empírica da cidade de Pelotas como candidata a Destino MICE Regional. A metodologia é qualitativa, sendo um estudo de caso que utiliza dados primários através de informação coletada nos sites de promoção turística oficiais do município. Conclui-se que a cidade de Pelotas, situada no sul do Estado do Rio Grande do Sul, possui condições de tornar-se um Destino MICE Regional, porém se recomenda uma melhoria no planejamento turístico, em términos de focalizar no desenvolvimento dos atributos de competitividade MICE, e especialmente uma melhoria na qualidade e quantidade das informações sobre suas capacidades como Destino MICE.
Recent Efforts in the Discovery of Urease Inhibitor Identifications
Authors: Song Wan-Qing , Liu Mei-Ling , Li Su-Ya , Xiao Zhu-Ping 
Published: November 2021

Abstract:
Urease is an attractive drug target for designing anti-infective agents against pathogens such as Helicobacter pylori, Proteus mirabilis, and Ureaplasma urealyticum. In the past century, hundreds of medicinal chemists focused their efforts on explorations of urease inhibitors. Despite the FDA’s approval of acetohydroxamic acid as a urease inhibitor for the treatment of struvite nephro-lithiasis and the widespread use of N-(n-butyl)thiophosphoric triamide as a soil urease inhibitor as nitrogen fertilizer synergists in agriculture, urease inhibitors with high potency and safety are urgently needed. Exploration of novel urease inhibitors has therefore become a hot research topic recently. Herein, inhibitors identified worldwide from 2016 to 2021 have been reviewed. They structurally belong to more than 20 classes of compounds such as urea/thioure analogues, hydroxamic acids, sul-fonamides, metal complexes, and triazoles. Some inhibitors showed excellent potency with IC50 val-ues lower than 10 nM, having 10000-fold higher potency than the positive control thiourea.
The Effects of Clinical Factors and Neonatal Morbidities on Hearing Screening among Neonatal Admissions
Authors: Nuseir Amjad , Zaitoun Maha , Albalas Hasan , Alomari Ahmad , Khasawneh Waseem , Khamees Almu'tasim 
Published: November 2021

Background:
Hearing loss is an important disorder affecting newborns admitted to
NICU. A national hearing screening program using otoacoustic emission testing is an essential tool
to identify hearing loss early in neonates, enabling early intervention to avoid further challenges of
pediatric deafness. On the other hand, a delay of the auditory pathway maturation in preterm babies
compared to term newborns has already been suggested in the literature. Taking this information into
account, in this paper, we aim to identify the best time to perform NICU infant hearing screening
tests.

Objectives:
We aim to study the clinical factors and neonatal morbidities that may affect neonatal
hearing screening results using otoacoustic emission test in order to decrease the false-positive test
results that increase parental anxiety and increase the need for subsequent investigations.

Methods:
This is a prospective cross-sectional study that included 204 infants who were admitted
to a tertiary referral hospital NICU unit between September 2017 and May 2018. Both transients
evoked otoacoustic emissions (TEOAE), and distortion product otoacoustic emission (DPOAE)
screening tests were performed in order to screen hearing loss.

Results:
Our study included 204 infants, 52.9 % of which were males and 47.1 % females. There
were correlations between both hyperbilirubinemia and ventilation ≥ 5 days and the failure rate of
the first OAE test results among NICU infants where the P-values were (p=0.0133) and
(p=0.0456), respectively. Moreover, 165 babies (80.9 %) passed the first OAE with a mean birth
weight of 2759 gram and mean maternal age of 30.6 years, while 39 babies (19.1 %) failed the test
with a mean birth weight of 2436 gram and a mean maternal age of 32 years. There was no statistically
significant relation between both maternal age and birth weight with failure of the first screening
test.

Conclusion:
Our study suggests a higher failure rate of the first OAE in NICU infants who had hyperbilirubinemia
or ventilation ≥ 5 days. Therefore, our recommendation is to postpone the first
phase of hearing screening for those infants until the first scheduled vaccine appointment to
achieve high compliance to attendance and decrease distress to the family that can be associated
with false-negative results of the test.
Pediatrics for Disability: A Comprehensive Approach to Children with
Syndromic Psychomotor Delay
Authors: Tarani Luigi , Rasio Debora , Tarani Francesca , Parlapiano Giovanni , Valentini Diletta , Dylag Katarzyna Anna , Spalice Alberto , Paparella Roberto , Fiore Marco 
Published: November 2021

:
Intellectual disability is the impairment of cognitive, linguistic, motor and social skills
that occurs in the pediatric age and is also described by the term “mental retardation”. Intellectual
disability occurs in 3-28 % of the general population due to a genetic cause, including chromosome
aberrations. Among people with intellectual disabilities, the cause of the disability was identified
as a single gene disorder in up to 12 %, multifactorial disorders in up to 4 %, and genetic disorders
in up to 8.5 %. Children affected by a malformation syndrome associated with mental retardation
or intellectual disability represent a care challenge for the pediatrician. A multidisciplinary team is
essential to manage the patient, thereby controlling the complications of the syndrome and promoting
the correct psychophysical development. This requires continuous follow-up of these children
by the pediatrician, which is essential for both the clinical management of the syndrome and facilitating
the social integration of these children.
Patient Engagement in the Design of a Mobile Health App That Supports Enhanced Recovery Protocols for Cardiac Surgery: Development Study
Authors: Chudyk Anna M , Ragheb Sandra , Kent David , Duhamel Todd A , Hyra Carole , Dave Mudra G , Arora Rakesh C , Schultz Annette SH 
Published: November 2021

Background
Despite the importance of their perspectives, end users (eg, patients, caregivers) are not typically engaged by academic researchers in the development of mobile health (mHealth) apps for perioperative cardiac surgery settings.

Objective
The aim of this study was to describe a process for and the impact of patient engagement in the development of an mHealth app that supports patient and caregiver involvement with enhanced recovery protocols during the perioperative period of cardiac surgery.

Methods
Engagement occurred at the level of consultation and took the form of an advisory panel. Patients who underwent cardiac surgery (2017-2018) at St. Boniface Hospital (Winnipeg, Manitoba) and their caregivers were approached for participation. A qualitative exploration determined the impact of patient engagement on the development (ie, design and content) of the mHealth app. This included a description of (1) the key messages generated by the advisory panel, (2) how key messages were incorporated into the development of the mHealth app, and (3) feedback from the developers of the mHealth app about the key messages generated by the advisory panel.

Results
The advisory panel (N=10) generated 23 key messages to guide the development of the mHealth app. Key design-specific messages (n=7) centered around access, tracking, synchronization, and reminders. Key content-specific messages (n=16) centered around medical terms, professional roles, cardiac surgery procedures and recovery, educational videos, travel, nutrition, medications, resources, and physical activity. This information was directly incorporated into the design of the mHealth app as long as it was supported by the existing functionalities of the underlying platform. For example, the platform did not support the scheduling of reminders by users, identifying drug interactions, or synchronizing with other devices. The developers of the mHealth app noted that key messages resulted in the integration of a vast range and volume of information and resources instead of ones primarily focused on surgical information, content geared toward expectations management, and an expanded focus to include caregivers and other family members, so that these stakeholders may be directly included in the provision of information, allowing them to be better informed, prepare along with the patient, and be involved in recovery planning.

Conclusions
Patient engagement may facilitate the development of a detail-oriented and patient-centered mHealth app whose design and content are driven by the lived experiences of end users.
Social Media and Health Care (Part II): Narrative Review of Social Media Use by Patients
Authors: Farsi Deema , Martinez-Menchaca Hector R , Ahmed Mohammad , Farsi Nada 
Published: November 2021

BackgroundPeople are now connected in a borderless web-based world. The modern public, especially the younger generation, relies heavily on the internet as the main source of health-related information. In health care, patients can use social media for more tailored uses such as telemedicine, finding a provider, and for peer support.ObjectiveThe aim of this narrative review is to discuss how social media has been used in the health care industry from the perspective of patients and describe the main issues surrounding its use in health care.MethodsBetween March and June 2020, a review of the literature was conducted on PubMed, Google Scholar, and Web of Science for English studies that were published since 2007 and discussed the use of social media in health care. In addition to only English publications that discussed the use of social media by patients, publications pertaining to ethical and legal considerations in the use of social media were included. The studies were then categorized as health information, telemedicine, finding a health care provider, peer support and sharing experiences, and influencing positive health behavior. In addition, two more sections were added to the review: issues pertaining to social media use in health care and ethical considerations.ResultsInitially, 75 studies were included. As the study proceeded, more studies were included, and a total of 91 studies were reviewed, complemented by 1 textbook chapter and 13 web references. Approximately half of the studies were reviews. The first study was published in 2009, and the last was published in 2021, with more than half of the studies published in the last 5 years. The studies were mostly from the United States (n=40), followed by Europe (n=13), and the least from India (n=1). WhatsApp or WeChat was the most investigated social media platform.ConclusionsSocial media can be used by the public and patients to improve their health and knowledge. However, due diligence must be practiced to assess the credibility of the information obtained and its source. Health care providers, patients, and the public need not forget the risks associated with the use of social media. The limitations and shortcomings of the use of social media by patients should be understood.
A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation
Authors: Ko Hoon , Huh Jimi , Kim Kyung Won , Chung Heewon , Ko Yousun , Kim Jai Keun , Lee Jei Hee , Lee Jinseok 
Published: November 2021

Background
Detection and quantification of intra-abdominal free fluid (ie, ascites) on computed tomography (CT) images are essential processes for finding emergent or urgent conditions in patients. In an emergency department, automatic detection and quantification of ascites will be beneficial.

Objective
We aimed to develop an artificial intelligence (AI) algorithm for the automatic detection and quantification of ascites simultaneously using a single deep learning model (DLM).

Methods
We developed 2D DLMs based on deep residual U-Net, U-Net, bidirectional U-Net, and recurrent residual U-Net (R2U-Net) algorithms to segment areas of ascites on abdominopelvic CT images. Based on segmentation results, the DLMs detected ascites by classifying CT images into ascites images and nonascites images. The AI algorithms were trained using 6337 CT images from 160 subjects (80 with ascites and 80 without ascites) and tested using 1635 CT images from 40 subjects (20 with ascites and 20 without ascites). The performance of the AI algorithms was evaluated for diagnostic accuracy of ascites detection and for segmentation accuracy of ascites areas. Of these DLMs, we proposed an AI algorithm with the best performance.

Results
The segmentation accuracy was the highest for the deep residual U-Net model with a mean intersection over union (mIoU) value of 0.87, followed by U-Net, bidirectional U-Net, and R2U-Net models (mIoU values of 0.80, 0.77, and 0.67, respectively). The detection accuracy was the highest for the deep residual U-Net model (0.96), followed by U-Net, bidirectional U-Net, and R2U-Net models (0.90, 0.88, and 0.82, respectively). The deep residual U-Net model also achieved high sensitivity (0.96) and high specificity (0.96).

Conclusions
We propose a deep residual U-Net–based AI algorithm for automatic detection and quantification of ascites on abdominopelvic CT scans, which provides excellent performance.
Praktik mistisisme Jawa dalam novel Partikel karya Dewi Lestari
Authors: Setiawan, M.Pd Arif , Musaffak Musaffak 
Published: November 2021

Mistisisme dalam tataran masyarakat Jawa menjadi sebuah simbol yang digunakan dalam kehidupan, terutama dalam konteks beragama. Penelitian ini bertujuan untuk mendeskripsikan praktik mistisisme Jawa dalam novel Partikel karya Dewi Lestari. Hal ini didasari oleh realitas bahwa pengarang termasuk ke dalam generasi yang tumbuh dan berkembang di lingkungan modern. Penelitian ini menggunakan metode deskriptif kualitatif, pendekatan yang digunakan adalah sosiologi sastra. Sumber data penelitian ini adalah novel Partikel karya Dewi Lestari yang diterbitkan oleh PT Bentang Pustaka dengan jumlah 490 halaman pada tahun 2012. Data dalam penelitian ini mencakup satuan cerita yang terwujud dalam dialog, monolog, paragraf, sekuen cerita, bagian kalimat, maupun narasi tokoh yang menggambarkan praktik mistisisme Jawa dalam novel Partikel karya Dewi Lestari. Pengumpulan data dilakukan dengan langkah (a) membaca sumber data; (b) unitizing (mengambil data yang tepat dengan cara menandai teks; serta (c) mencatat dan menginventarisasi teks yang relevan. Setelah semua data terkumpul, maka data dianalisis berdasarkan fokus penelitian yang lebih menekankan pada praktik mistisisme Jawa. Hasil penelitian menunjukkan bahwa dalam novel Partikel karya Dewi Lestari menampilkan praktik mistisisme Jawa pada tataran sarengat/syariat dan tarekat. Praktik mistisisme Jawa tokoh utama pada tataran sarengat/syariat dibuktikan dengan (1) percaya terhadap jin & setan dan (2) percaya pada mitos-mitos, sedangkan pada tataran tarekat dibuktikan dengan percaya dan upaya yang dilakukan tokoh untuk menjumpai Tuhan. Berdasarkan hasil penelitian, maka dapat ditarik kesimpulan bahwa praktik mistisisme Jawa dalam novel Partikel karya Dewi Lestari pada tataran syariat dan tarekat.
Features and themes of poetry in KOPI (komunitas puisi Indonesia) facebook group
Authors: Santoso Sugeng , Artika I Wayan , Wahyuni Ni Made Sania Indri 
Published: November 2021

Going along with the development of technology, literary disciplines also have been developing. Cyber literature becomes popular in this digitalization era which explores the existence of the internet as the medium. One of the large cyber literary communities on Facebook is KOPI (Komunitas Puisi Indonesia) with 64 thousand members. Due to the insufficient research analyzing poetry in the Facebook group, this research analyzed the features of poetry and the themes of poetry in KOPI (Komunitas Puisi Indonesia). Descriptive and qualitative approaches were used in this research. Observation and documentation were used as the techniques in data collecting. The observation was done by reviewing the group’s situation and the documentation is done by reviewing the poetry collections that had been uploaded in this research from the beginning until the middle of February 2021. The data analysis techniques used Miles and Huberman techniques which include: (1) data reduction, (2) data serving, and (3) conclusion/verification withdrawal. The results of this research showed that the dominant poetry features were image illustration and the themes that were used by KOPI group members in writing poetry included the physical themes, moral themes, social themes, egoic themes, divine themes. Physical theme with the most widely used type of love. It can be concluded that the physical theme with the type of “love” is the choice of the theme that the author most favors.
Effect of Gypsum and Etepon on Crop Yield Siamese Orange (Citrus Nobilis Var. Microcarpa L.)
Authors: A. A. Istri Tyagita Varenia  , Ni Putu Anom Sulistiawati  , Ni Komang Alit Astiari  
Published: November 2021

This study aims to determine the effect of Gypsum and Etepon on the yield of Siamese orange (Citrus nobilis Var Microcarpa. L) conducted in Belancan Village, Kintamani District, Bangli Regency from December 2020 to July 2021. This study used a randomized block design (RAK) with 2 factors arranged in a factorial manner. The first factor that was tried was the dose of gypsum fertilizer (G) which consisted of 4 levels, namely: G0 (0 g/tree), G1 (250 g/tree), G2 (500 g/tree) and G3 (750 g/tree. While the second factor is the concentration of etepon (E) which consists of 3 levels, namely: E0 (0 ml/l water/tree), E1 (0.75 ml//l water/tree) and E2 (1.5 ml/l water)/tree). Thus, there were 12 combination treatments, each of which was repeated 3 times so that 36 citrus trees were needed. The results showed that the interaction between the dose of gypsum and the concentration of etepon had no significant effect on all observed variables. The highest harvested fruit weight per tree was obtained at a dose of gypsum 750 g/tree which was 6.32 kg or an increase of 70.35% when compared to treatment without gypsum which was only 3.71 kg. The highest harvested fruit weight per tree was obtained in the etepon treatment with a concentration of 1.5 ml/l/tree, which was 6.54 kg, an increase of 51.38% compared to the treatment without etepon, which was only 4.32 kg.

Keywords: dose, etepon, gypsum, Siamese orange, yield
Identification of Arbuscular Mychorizae Fungi on Oil Palm in Bireuen, Aceh
Authors: Rita Zaitun Ritaqwin , Mizan Maulana  , Nazalia  
Published: November 2021

Abstract

Oil palm plantations in Aceh , especially in Bireuen, are generally planted on red-yellow podzolic soil types. Arbuscular mycorrhizal fungi (AMF) are fungi who are symbiotically associated with 97% of plant species. This study aims to identify the type and population of mycorrhizal spores from oil palm rhizosphere soil samples using culture trapping techniques (maize, sorghum, kudzu). This research was carried out in a greenhouse and Experimental Field, Faculty of Agriculture, Islamic National University of Indonesia, Bireuen, Aceh. Isolation, identification and observation of AMF colonization on plant roots was carried out at the Laboratory of Soil Biology, Faculty of Agriculture, Syiah Kuala University. The parameters included the number of arbuscular mycorrhizal fungi spores and the percentage of root colonization using the trapping culture method. The trapping culture method used 50 g of soil samples on oil palm rhizosphere which aged 5 months, 7 years, 9 years and 12 years. The results showed that the most dominant mycorrhizae found was the Glomus type. The mycorrhizae spores types found in the trapping culture were Glomus, Acaulospora and Gigaspora. The host plant that produced the most AMF spores was sorghum, while the highest AMF colonization of the three host plants was found in the roots of maize plants (78%) with very high criteria.
Keywords: Oil palm, Culture trapping, AMF
Pediatric Rotary Files: Evolution to Revolution
Authors: Dr Neeta S Padmawar  , Dr Aparna Palekar  , Dr Savita Thakkannavar  , Dr Shridhar Shetty  , Dr Shilpa Pharande  , Dr Swati Pustake  
Published: November 2021

The main goal of pulp therapy in primary dentition is to preserve the primary tooth thus protecting future normal occlusion. Routinely, pulp debridement and canal shaping are done by manual H-files, K-files, Broach, etc. Manual instrumentation may be time- consuming, thus impacting the behaviour of the child negatively. Thus arises the need for alternate instrumentation which will reduce the time required for treatment with better treatment outcomes. In 1988, Walia et al. introduced Nickel-Titanium (Ni-Ti), which revolutionized the discipline of Endodontics. These Ni-Ti files have advantage of shape memory and super elasticity thus improving the canal preparation and resulting in better shaped canals. In 2002, for first time Barr et al reported the use of rotary Ni-Ti files for the therapeutic purpose during Pulpectomy procedure in pediatric patient. He observed better acceptance by pediatric patient and good quality obturation. Till 2016, pulpectomy procedures were accomplished by the combination of hand files and adult rotary files. Adult rotary files are designed according to the morphology for permanent teeth and adult jaw size, thus the use of adult rotary files are in primary teeth may result in lateral perforation due to softer dentine of roots of primary teeth and may cause discomfort to the child thus making child unco-operative. But in 2016, Ganesh et al., pioneered the specialization of Paediatric Endodontics with his invention of specially designed rotary files. Their shape was specially designated for application in tortuous canals of primary teeth. Presently, a variety of pediatric rotary files like Kedo-STM (India), Pro AF Baby GoldTM (India),PrimePedoTM (India), DXL-ProPedoTM (India), NeolixTM (France),Denco® Kids files (China) and, Sani® Kid rotary files (China). This review is an album of these newer files and clinical and in-vitro research on them.