bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dysfunction of the mucous membrane in the pathogenesis of chronic diseases of the nasal cavity
Authors: Nikiforova G. N. , Artamonova P. S. , Shevchik E. A. 
Published: December 2021

Performing not only respiratory, but also protective, olfactory, aesthetic and a number of other functions, the nose is an important part of the upper respiratory tract. The mucous membrane of the nasal cavity is the first protective barrier of the body that protects against the effects of adverse environmental factors, carrying out warming, purification and neutralization of the inhaled air. This mission is provided by the activity of the multilayered columnar ciliated epithelium, consisting of three main types of cells: ciliate, goblet and basal. The main protective mechanism in the nasal cavity is mucociliary clearance, carried out by means of nasal mucus and beating of cilia unidirectional towards the nasopharynx with a frequency of up to 1000 per minute. Violation of the integrity and disruption of the physiological functions of the mucous membrane of the nasal cavity leads to the development of pathological processes, which in turn can lead to a failure in the work of other organs and systems of the body. To date, about 16-18% of all diseases of the ENT organs are chronic forms of rhinitis. According to the ICAR classification, which is based on the pathophysiological mechanisms of the development of rhinitis, allergic and non-allergic forms are distinguished. Common to various forms is the effect of certain factors on the mucous membrane of the nasal cavity and, as a consequence, a violation of the mechanisms of its work.One of the forms of chronic rhinitis, caused by thinning of the mucous membrane and severe disorders of mucociliary transport, is atrophic rhinitis. The main symptoms of the disease are dryness, the formation of crusts in the nasal cavity, periodic bleeding. The approach to the treatment of acute and chronic processes against the background of atrophic changes in the nasal cavity should be comprehensive and aimed at restoring the physiological functions of the mucous membrane and the mechanisms of mucociliary transport.
Study of risk factors for the osteoporosis development in rheumatoid arthritis in real clinical practice
Authors: Papichev E. V. , Akhverdyan Yu. R. , Polyakova Yu. V. , Sivordova L. E. , Zavodovskii B. V. 
Published: December 2021

Introduction. Osteoporosis is a common complication of rheumatoid arthritis. Its development is associated with the mechanisms underlying in the progression of autoimmune inflammatory diseases and therapeutic approaches used for them. The study of risk factors for osteoporosis can contribute to the clarification of its pathogenesis components, as well as the development of new methods for prevention, diagnosis and treatment of this condition.Aim. To study the role of anamnestic, clinical and laboratory factors for secondary osteoporosis in women with rheumatoid arthritis.Materials and methods. 102 women with rheumatoid arthritis were enrolled in our study. Exclusion criterias were type 2 diabetes mellitus, hepatic cirrhosis, hepatocarcinoma and level of alanine aminotransferase ≥ than 3 upper limit ofnormal. The cumulative dose, duration and daily dose of glucocorticoids (GC) were determined by patient intake. All patients undergone standard clinical and immunological examination. Serum fetuin-A, 25-hydroxycalciferol, C-telopeptide of collagen I type, N-terminal propeptide of collagen I type levels were determined using ELISA. X-ray of afflicted joints and dual-energy x-ray absorptiometry were performed. Statistical analysis was performed using conventional methods. Forced data entry was used to perform multiple logistic regression. Hereinafter data is presented as odds ratio (OR) and 95% confirmation intervals (CI).Results. OR for osteoporosis were higher in women of age ≥ 58.5 years (OR 1,07 (1.02–1.12)), body mass index (BMI) ≤ 27 kg/m2 (OR 1.1 (1.01–1.2)), cumulative dose of GC ≥ 7.6 g (OR 1.09 (1.02–1.17), serum fetuin-A levels ≤ 660 μg/ml (OR 1,05 (1,01–1,09) and if the duration of GC intake is more than 3 months (hereinafter if dose of glucocorticoids is ≥ 5 mg for prednisolone daily) (OR 12.3 (4.12–36.5). Adjusted OR for osteoporosis were higher in women of age ≥ 58.5 years old (adjOR 1.08 (1.01–1.16), serum fetuin-A levels ≤ 660 μg/ml (adjOR 1.08 (1.01–1.15) andif the duration of GC intake is ≥ than 3 months (adjOR 12.1 (1.44–102.3).Conclusions. Women with RA of ≥ than 58.5 years old, duration of GCs intake more than 3 months and serum fetuin-A levels ≤ than 660 μg/ml had higher odds for osteoporosis.These are independent factors for osteoporosis in women with rheumatoid arthritis, whichshould be used in patient’s management.
Facile fabrication of low-cost activated carbon bonded polyethersulfone membrane for efficient bacteria and turbidity removal
Authors: Prihandana Gunawan Setia , Sururi Ahmad , Sriani Tutik , Yusof Farazila , Jamaludin Mohd Fadzil , Mahardika Muslim 
Published: December 2021

AbstractThe current research aimed to fabricate a cost-effective activated carbon disc for bacteria and turbidity removal in contaminated water using polyethersulfone membrane solution as a bonding agent. The mixing compatibility and bonding stability of the blend activated carbon disc were studied with a bonding strength test. The morphology of activated carbon discs was studied by a microscope. The activated carbon discs had a thick dense layer between the powder. Activated carbon discs significantly removed the total coliforms populations (99%) when evaluated against river water whilst removal by the powder was only up to 90%. The turbidity removal efficiency for the activated carbon increased from 29%-79% with the utilization of the membrane as the bonding agent in forming the disc. However, the pH of water treated by the activated carbon powder and disc did not change significantly, yet it lay within the pH range of safe drinking water (6.5–7.7). It revealed the important role of PES membranes for the activated carbon discs to improve coliform and turbidity removal in the water, ensuring the quality of water resources.
MORTALIDADE POR ACIDENTES DE TRÂNSITO EM CAPITAL DO NORDESTE BRASILEIRO, 2010-2014
Authors: Wingerter Denise Guerra 
Published: December 2021

Acidentes de trânsito representam grave problema de saúde e são considerados evitáveis em sua totalidade. O Brasil ocupa o terceiro lugar internacional em número de mortes no trânsito. Objetiva-se apresentar o perfil desta mortalidade na capital do Rio Grande do Norte. Metodologia: Pesquisa observacional com dados do Sistema de Informações sobre Mortalidade, ocorridos no município de Natal/RN entre 2010-2014. Resultados: Maior parte dos óbitos são do sexo masculino (82%) solteiros (53%), de cor preta (73%) abaixo de 39 anos (44%), em finais de semana (47%) período noturno (31%) e ocupantes de motos (30%). Escolaridade, ocupação e especificação do veículo indicam preenchimento deficiente da Declaração de Óbito. Taxa de mortalidade decresceu no período de 4,85 para 2,90 óbitos/100.000habitantes, queda de 40%, porém a taxa entre motociclistas aumentou 31%. Conclusões: Necessidade de políticas voltadas para um público-alvo específico e necessidade de capacitação para o preenchimento correto dos dados.
MODELAGEM PARAMÉTRICA
Authors: Sousa Nilberto , Dionisi Alessio , Castro Clodoaldo 
Published: December 2021

Este artigo apresenta a proposta arquitetônica elaborada pela equipe que obteve o segundo lugar no concurso interno, intitulado Exercício de Concepção de um Elemento Arquitetônico, da disciplina Oficina de Projeto Computacional do Programa de Pós-graduação Profissional em Arquitetura, Projeto e Meio Ambiente da UFRN/Natal. O objetivo do concurso era projetar uma cobertura de forma complexa, que conectasse os prédios da graduação e da pós-graduação do curso de Arquitetura. Dentre as diretrizes e restrições impostas pelo enunciado do exercício, destacam-se a concepção em modelagem paramétrica, o uso da madeira como material principal, o recobrimento da estrutura em telha, a preservação da espécie arbórea existente e a escolha por materiais disponíveis na universidade. O conceito da proposta é reverter restrições em potencialidades, e o projeto reinterpreta uma técnica construtiva vernacular, a oca indígena, cuja estabilidade estrutural resulta do arqueamento de um pontalete fincado na terra. A ripa é o material escolhido para compor a estrutura arqueada. O uso do Grasshopper se constituiu numa alternativa aos processos projetuais tradicionais como croquis à mão livre, modelagem em softwares Sketchup, maquete e mockup. O benefício do programa reside na rapidez com que formas são geradas sem que, para isso, novos modelos sejam elaborados. Ele é uma mudança de paradigma em relação aos softwares CAD convencionais, pois o processo inicial de projeto se volta mais aos parâmetros que estabelecem a forma do que o próprio desenho da forma em si. A interoperabilidade do Grasshopper com programas de cálculo estrutural é outro aspecto relevante desse processo projetual.
Auxetic Polymer Foams: Production, Modeling and Applications
Authors: Hamdi Ouassim , Rodrigue Denis 
Published: December 2021

:Auxetic materials have high potential due to their exceptional properties resulting from a negative Poisson’s ratio. Recently, several auxetic polymer-based materials have been developed. In fact, several applications are looking for a lightweight material (less material consumed in production and transport) while having high mechanical performances (impact absorption, rigidity, strength, resistance, etc.). So, a balance between density and toughness/strength is highly important, especially for military, sporting, and transport applications. So auxetic materials (especially foams) can provide high impact protection while limiting the material’s weight. This article presents a review of recent advances with a focus on auxetic polymers, with particular emphasis on the auxetic polymer foams in terms of their fabrication methods and processing conditions (depending on the nature of the cellular structure), the effect of the fabrication parameters on their final properties, as well as their models and potential applications.
Process and Outcome Evaluations of Smartphone Apps for Bipolar Disorder: Scoping Review
Authors: Tatham Iona , Clarke Ellisiv , Grieve Kelly Ann , Kaushal Pulkit , Smeddinck Jan , Millar Evelyn Barron , Sharma Aditya Narain 
Published: December 2021

Background
Mental health apps (MHAs) provide opportunities for accessible, immediate, and innovative approaches to better understand and support the treatment of mental health disorders, especially those with a high burden, such as bipolar disorder (BD). Many MHAs have been developed, but few have had their effectiveness evaluated.

Objective
This systematic scoping review explores current process and outcome measures of MHAs for BD with the aim to provide a comprehensive overview of current research. This will identify the best practice for evaluating MHAs for BD and inform future studies.

Methods
A systematic literature search of the health science databases PsycINFO, MEDLINE, Embase, EBSCO, Scopus, and Web of Science was undertaken up to January 2021 (with no start date) to narratively assess how studies had evaluated MHAs for BD.

Results
Of 4051 original search results, 12 articles were included. These 12 studies included 435 participants, and of these, 343 had BD type I or II. Moreover, 11 of the 12 studies provided the ages (mean 37 years) of the participants. One study did not report age data. The male to female ratio of the 343 participants was 137:206. The most widely employed validated outcome measure was the Young Mania Rating Scale, being used 8 times. The Hamilton Depression Rating Scale-17/Hamilton Depression Rating Scale was used thrice; the Altman Self-Rating Mania Scale, Quick Inventory of Depressive Symptomatology, and Functional Assessment Staging Test were used twice; and the Coping Inventory for Stressful Situations, EuroQoL 5-Dimension Health Questionnaire, Generalized Anxiety Disorder Scale-7, Inventory of Depressive Symptomatology, Mindfulness Attention Awareness Scale, Major Depression Index, Morisky-Green 8-item, Perceived Stress Scale, and World Health Organization Quality of Life-BREF were used once. Self-report measures were captured in 9 different studies, 6 of which used MONARCA. Mood and energy levels were the most commonly used self-report measures, being used 4 times each. Furthermore, 11 of the 12 studies discussed the various confounding factors and barriers to the use of MHAs for BD.

Conclusions
Reported low adherence rates, usability challenges, and privacy concerns act as barriers to the use of MHAs for BD. Moreover, as MHA evaluation is itself developing, guidance for clinicians in how to aid patient choices in mobile health needs to develop. These obstacles could be ameliorated by incorporating co-production and co-design using participatory patient approaches during the development and evaluation stages of MHAs for BD. Further, including qualitative aspects in trials that examine patient experience of both mental ill health and the MHA itself could result in a more patient-friendly fit-for-purpose MHA for BD.
A Novel, Scalable Social Media–Based Intervention (“Warna-Warni Waktu”) to Reduce Body Dissatisfaction Among Young Indonesian Women: Protocol for a Parallel Randomized Controlled Trial
Authors: Garbett Kirsty May , Craddock Nadia , Haywood Sharon , Nasution Kholisah , White Paul , Saraswati L Ayu , Medise Bernie Endyarni ,   Girl Effect,   Percolate Galactic, Diedrichs Phillippa C , Williamson Heidi 
Published: December 2021

Background
Despite the prevalence of body dissatisfaction among young Indonesian women and its consequential negative impacts, there are currently no evidence-based, culturally appropriate interventions to tackle this issue. Therefore, there is a need to develop scalable, cost-effective, and accessible interventions to improve body image among this population.

Objective
This paper describes the study protocol of a parallel randomized controlled trial to evaluate the effectiveness of Warna-Warni Waktu, a social media–based intervention that aims to reduce state and trait body dissatisfaction and improve mood among young Indonesian women aged 15-19 years.

Methods
The trial will take place online. Approximately 1800 young women from 10 cities in Indonesia, evenly split across the ages of 15-19 years, will be recruited via a local research agency’s established research panel. Participants will be randomly allocated to the intervention condition or a waitlist control condition. The intervention consists of six 5-minute videos, with each video supplemented with up to five brief interactive activities. The videos (and associated activities) will be delivered at a rate of one per day across 6 days. All participants will complete three self-report assessments: at baseline (Day 1), 1 day following the intervention (Day 9), and 1 month following the intervention (Day 36). The primary outcome will be change in trait body dissatisfaction. Secondary outcomes include change in internalization of appearance ideals, trait mood, and skin shade satisfaction. Intervention effectiveness on these outcomes will be analyzed using linear mixed models by a statistician blinded to the randomized condition. Intervention participants will also complete state measures of body satisfaction and mood before and after watching each video to assess the immediate impact of each video. This secondary analysis of state measures will be conducted at the within-group level.

Results
Recruitment began in October 2021, with baseline assessments underway shortly thereafter. The results of the study will be submitted for publication in 2022.

Conclusions
This is the first study to evaluate an eHealth intervention aimed at reducing body dissatisfaction among young Indonesian women. If effective, the intervention will be disseminated to over half a million young women in Indonesia via Facebook, Instagram, and YouTube.

Trial Registration
ClinicalTrials.gov NCT05023213; https://clinicaltrials.gov/ct2/show/NCT05023213

International Registered Report Identifier (IRRID)
PRR1-10.2196/33596
Silicic magmas in the Michoacán-Guanajuato Volcanic Field: an overview about plumbing systems, crustal storage and genesis processes
Authors: Sosa-Ceballos Giovanni , Boijseauneau-López Mario Emmanuel , Pérez-Orozco Juan Daniel , Cifuentes-Nava Gerardo , Bolós Xavier , Perton Mathieu , Simón-Velázquez David 
Published: December 2021

The origin of silicic rocks in the Michoacán-Guanajuato volcanic field (MGVF) has been understudied since the volcanic field attracted the attention of researchers. Using geochemical, petrological and structural data from the literature, here we propose a model for the origin of silicic magmas. We found that all volcanic rocks known to date in the MGVF can be divided in 40 % andesite, 33 % basaltic andesite, 15 % basalt, 2 % trachybasalt to trachyandesite, and 10 % dacite-rhyolite. The structural systems that deformed the crust in the MGVF are NNW-SSE-oriented normal faults of the Taxco-San Miguel de Allende fault system, developed during the Oligocene, and the Morelia-Acambay fault system consisting of ENE-SSW to E-W sinistral strike-slip faults developed during the Oligocene-Miocene. In addition to bibliographic data, we present a gravimetric-magnetometric model to investigate the characteristics of the local basement where magmas acquire their final silicic composition, and a seismic tomography model to investigate the deep plumbing system that contribute to form the silicic rocks emplaced on the surface. The only report of assimilation experiments we found in the MGVF literature suggest that plagioclase and pyroxene are more easily digested than quartz by hotter magmas. The digestion of these mineral phases has a direct consequence on the generation of dacites and rhyolites. We propose that regardless of the genesis of andesitic melts, such intermediate magmas arrive to the upper-crust and are forced to evolve within local compression zones where they melt the local granitic basement and form crystal mushes. The compositional variability of silicic rocks in the MGVF is a consequence of the variable mixing between the intermediate magmas and the granitic partial melts.
Taladradores de la madera (Scolytidae) en plantaciones de Tectona grandis L.f. (teca) del Trópico ecuatoriano
Authors: Solano Apuntes Edison Hidalgo , Belezaca Pinargote Carlos Eulogio , López Tobar Rolando Manuel , Macías Suárez Keberlin Patricia 
Published: December 2021

Se evaluó la supervivencia de seis especies de peces nativos continentales (Andinoacaras rivulatus , Cichlasoma festae, Ichthyoelephas humeralis, Brycon dentex.Curimatorbis boulengeri, y Hoplias microhelepis) en su medio natural, en base a los datos de capturas en un rango de cinco años, realizada por ocho empresas de pesca extractiva, en el rio Vinces, en las zonas de Quevedo, Mocache y buena fé, para tal efecto se consideró el lugar de captura, la talla de las especies en estudio, cantidad en Kg de biomasa , con la finalidad de determinar el incremento o disminución de la población natural; para determinar el decremento de talla se consideró el peso medio de captura y la longitud estándar media. Los datos fueron tomados de las capturas de 8 empresas de pesca extractiva de los cantones Quevedo, Mocache y Buena fé, Se determinó que existe una disminución del 66% de la biomasa de capturas en el quinquenio comprendido entre septiembre del 2015 a septiembre del 2019. El número de peces provenientes de la captura refleja una disminución para las siguientes especies: bocachico 73.33%, dica 46%, vieja azul 53.1%, mientras que algunas especies han incrementado el número de peces, la dama incremento en un 46%, la vieja colorada 13.64% y guanchiche 2.5%. la talla máxima de captura reportó una disminución promedio del 42%.
Decortication, thoracic omentalization, and pericardiectomy for treatment of severe fibrosing pleuritis in a cat
Authors: Sack Danny , Hyndman Philip , Milligan Melissa , Spector Daniel 
Published: December 2021

Abstract

CASE DESCRIPTION
A 5-year-old spayed female domestic shorthair cat was evaluated because of an acute onset of dyspnea and open-mouthed breathing.

CLINICAL FINDINGS
Thoracic radiography revealed pleural effusion and signs consistent with restrictive pleuritis, and results of preoperative CT were consistent with diffuse, severe restrictive pleuritis, bilateral pleural effusion, and pulmonary atelectasis. Thoracocentesis yielded a red, turbid fluid that was identified as chylous effusion with chronic inflammation.

TREATMENT AND OUTCOME
Exploratory thoracotomy revealed diffuse, severe fibrous adhesions between the mediastinum, heart, lung lobes, and thoracic wall, with a thick fibrous capsule enveloping all lung lobes. Surgical treatment consisted of complete pleural decortication, pericardiectomy, and thoracic omentalization. The cat remained hospitalized for 6 days, receiving oxygen supplementation, multimodal analgesia, and supportive care. Long-term home care consisted of prednisolone administration, rutin supplementation, and provision of a low-fat diet. At recheck examinations 3-, 7-, and 20-weeks postoperatively, the cat remained tachypneic, but was otherwise clinically normal without dyspnea or respiratory distress. Follow-up thoracic radiography revealed improved pulmonary expansion, decreased pleural effusion, and resolved pneumothorax.

CLINICAL RELEVANCE
Surgical management of fibrosing pleuritis secondary to idiopathic chylothorax in cats has historically resulted in poor outcomes. This report details the first successful use of complete decortication in the surgical management of severe fibrosing pleuritis in a cat.
The pattern of systemic inflammation index in normotensive non-dipper and dipper hypertensive patients
Authors: Emlek Nadir , Aydin Cihan 
Published: December 2021

Objective: Continuous inflammation at the level of the vascular endothelium plays an important role in the formation of hypertension. Diurnal blood pressure (BP) variation also is a risk factor for hypertensive target organ damage. This study planned to evaluate these inflammation processes in normotensive and hypertensive patients.

Methods: This study is observational cross-sectional cohort in-design. 151 patients with a prediagnosis of hypertension included. The patients were divided into three groups (group 1: dipper normotensive, group 2: non-dipper normotensive, group 3: dipper-hypertensive) based on the results of ambulatory blood pressure monitoring. The groups were compared in terms of systemic inflammation index (SII; platelet count×neutrophil count/lymphocyte count), neutrophil to lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and other inflammation processes.

Results: There was a significant difference between the three groups in terms of mean platelet volume (MPV) and red blood cell distribution width (RDW) levels (p=0.001 and p&lt;0.001, respectively). A statistically significant difference was found between the groups in terms of NLR, PLR, systemic inflammation index, lymphocyte-monocyte ratio (LMR). In subgroup analysis, NLR and systemic inflammation index were similar in group 2 and group 3, but higher than in group 1 in both groups. LMR was similar in group 2 and group 3 but lower than in group 1. In subgroup analysis PLR levels were similar in group 2 and group 3 but higher than group 1 in both groups.

Conclusion: This study showed that normotensive non-dipper patients had inflammation as much as dipper hypertensive patients according to measurement of MPV, RDW systemic inflammation index, PLR, NLR levels.