bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dissecting the midlife crisis: disentangling social, personality and demographic determinants in social brain anatomy
Authors: Kiesow Hannah , Uddin Lucina Q. , Bernhardt Boris C. , Kable Joseph , Bzdok Danilo 
Published: June 2021

AbstractIn any stage of life, humans crave connection with other people. In midlife, transitions in social networks can relate to new leadership roles at work or becoming a caregiver for aging parents. Previous neuroimaging studies have pinpointed the medial prefrontal cortex (mPFC) to undergo structural remodelling during midlife. Social behavior, personality predisposition, and demographic profile all have intimate links to the mPFC according in largely disconnected literatures. Here, we explicitly estimated their unique associations with brain structure using a fully Bayesian framework. We weighed against each other a rich collection of 40 UK Biobank traits with their interindividual variation in social brain morphology in ~10,000 middle-aged participants. Household size and daily routines showed several of the largest effects in explaining variation in social brain regions. We also revealed male-biased effects in the dorsal mPFC and amygdala for job income, and a female-biased effect in the ventral mPFC for health satisfaction.
Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry
Authors: Liew Chia Yen , Yen Chu-Chun , Chen Jien-Lian , Tsai Shang-Ting , Pawar Sujeet , Wu Chung-Yi , Ni Chi-Kung 
Published: June 2021

AbstractN-linked glycosylation is one of the most important protein post-translational modifications. Despite the importance of N-glycans, the structural determination of N-glycan isomers remains challenging. Here we develop a mass spectrometry method, logically derived sequence tandem mass spectrometry (LODES/MSn), to determine the structures of N-glycan isomers that cannot be determined using conventional mass spectrometry. In LODES/MSn, the sequences of successive collision-induced dissociation are derived from carbohydrate dissociation mechanisms and apply to N-glycans in an ion trap for structural determination. We validate LODES/MSn using synthesized N-glycans and subsequently applied this method to N-glycans extracted from soybean, ovalbumin, and IgY. Our method does not require permethylation, reduction, and labeling of N-glycans, or the mass spectrum databases of oligosaccharides and N-glycan standards. Moreover, it can be applied to all types of N-glycans (high-mannose, hybrid, and complex), as well as the N-glycans degraded from larger N-glycans by any enzyme or acid hydrolysis.
Unveiling the structure and dynamics of peeling mode in quiescent high-confinement tokamak plasmas
Authors: Kamiya Kensaku , Itoh Kimitaka , Aiba Nobuyuki , Oyama Naoyuki , Honda Mitsuru , Isayama Akihiko 
Published: June 2021

AbstractQuiescent high-confinement mode plasmas with edge-harmonic oscillations do not exhibit the explosive instabilities associated with edge-localized modes. Instead, an additional means of enhanced transport is considered to maintain the plasma edge under conditions just below the boundary of the peeling mode instability. Although the potential of the peeling mode has been widely recognized in plasma physics, no direct evidence for this mode has been revealed previously because decisive diagnostics were lacking. Herein, we report evidence of the structure and dynamical steady state of peeling mode in quiescent high-confinement mode. Edge-harmonic oscillations are dominated by fundamental mode at both the low- and high-field sides. Edge perturbations are confirmed to have kink parity and exhibit the frozen-in-condition predicted by linear stability analysis. The envelope signal of the fundamental mode exhibits repeated cycles of growth and damping in association with minor changes in the edge gradient. Results from this study are quantitatively consistent with limit-cycle-oscillation model.
Environmental DNA signatures distinguish between tsunami and storm deposition in overwash sand
Authors: Yap Wenshu , Switzer Adam D. , Gouramanis Chris , Marzinelli Ezequiel , Wijaya Winona , Yan Yu Ting , Dominey-Howes Dale , Labbate Maurizio , Srinivasalu Seshachalam , Jankaew Kruawun , Lauro Federico M. 
Published: June 2021

AbstractSandy onshore deposits from tsunamis are difficult to distinguish from storm deposits, which makes it difficult to assess coastal hazards from the geological record. Here we analyse environmental DNA from microbial communities preserved in known tsunami and storm-deposited sediments and intercalating soils and non-marine sediments near Cuddalore, India, and Phra Thong Island, Thailand. Both sites were impacted by the 2004 Indian Ocean Tsunami and a subsequent storm flooding event (2011 Cyclone Thane at Cuddalore and a 2007 storm at Phra Thong Island). We show that the microbial communities in the overwash deposits are significantly different from soil and sediments that are not derived by overwash processes at both locations. Our method also successfully discriminates between modern tsunami deposits and storm deposits. We suggest molecular techniques have the potential to accurately discriminate overwash deposits from catastrophic natural events.
Novel metagenome-assembled genomes involved in the nitrogen cycle from a Pacific oxygen minimum zone
Authors: Sun Xin , Ward Bess B 
Published: June 2021

Abstract
Oxygen minimum zones (OMZs) are unique marine regions where broad redox gradients stimulate biogeochemical cycles. Despite the important and unique role of OMZ microbes in these cycles, they are less characterized than microbes from the oxic ocean. Here we recovered 39 high- and medium-quality metagenome-assembled genomes (MAGs) from the Eastern Tropical South Pacific OMZ. More than half of these MAGs were not represented at the species level among 2631 MAGs from global marine datasets. OMZ MAGs were dominated by denitrifiers catalyzing nitrogen loss and especially MAGs with partial denitrification metabolism. A novel bacterial genome with nitrate-reducing potential could only be assigned to the phylum level. A Marine-Group II archaeon was found to be a versatile denitrifier, with the potential capability to respire multiple nitrogen compounds including N2O. The newly discovered denitrifying MAGs will improve our understanding of microbial adaptation strategies and the evolution of denitrification in the tree of life.
In situ structural reconstruction triggers the hydrothermal synthesis of hierarchical Ti-Beta zeolites for oxidative desulfurization
Authors: Ma Haikuo , Lin Haoyi , Liu Xiuquan , Lü Hongying , Zhu Zhiguo 
Published: June 2021

Hierarchical Ti-Beta zeolite was hydrothermally synthesized via in situ structural reconstruction strategy, triggering unique catalytic performance in oxidative desulfurization.
Conditioned medium of IGF1-induced synovial membrane mesenchymal stem cells increases chondrogenic and chondroprotective markers in chondrocyte inflammation
Authors: Marlina Marlina , Rahmadian Rizki , Armenia Armenia , Aviani Jenifer Kiem , Sholihah Ika Adhani , Kusuma Hanna Sari Widya , Azizah Alya Mardhotillah , Elida Nur , Widowati Wahyu 
Published: June 2021

Abstract
Recently, mesenchymal stem cells (MSCs) have been the most explored cells for cell therapy for osteoarthritis (OA) that can be obtained from various sources. Synovial membrane MSCs (SMMSCs) provide best potential for OA therapy, however they are not widely explored. Conditioned medium of SMMSCs (SMMSCs-CM) rich in growth factors and cytokines can inhibit apoptosis and increase chondrocytes cell proliferation. The aim of the present study was to determine growth factors content in SMMSCs-CM as well as the chondrogenic and chondroprotective markers expression in OA model after insulin-like growth factor (IGF)1-induced and non-induced SMMSCs-CM treatments. Chondrocyte cell line (CHON002) was induced by IL1β as OA model (CHON002 with IL1β (IL1β-CHON002)) and treated with SMMSCs-CM with or without IGF1 induction to determine its effectiveness in repairing OA cells model. ELISA was used to assay BMP2, fibroblast growth factor 18 (FGF18) and transforming growth factor (TGF) β1 (TGFβ1) levels in SMMSCs-CM, matrix metalloproteinase (MMP) 13 (MMP13) and a disintegrin and metalloproteinase with thrombospondin motif 4 (ADAMTS4) levels in OA cells model treated with SMMSCs-CM. RT-qPCR analyses were used to investigate the gene expression of SOX9, COL2, and COL10. CM from SMMSCs cultured and induced by IGF1 150 ng/mL was the most effective concentration for increasing the content of growth factor markers of SMMSCs-CM, which had successfully increased negative cartilage hypertrophy markers (SOX9 and COL2) and reduced hypertrophy markers (COL10, MMP13, and ADAMTS4). Preconditioning with IGF1 has better and very significant results in lowering MMP13 and ADAMTS4 levels. The present study supports IGF1 pre-conditioned SMMSCs-CM to develop a new therapeutic approach in OA improvement through its chondrogenic and chondroprotective roles.
Multi‐agent based protection scheme using current‐only directional overcurrent relays for looped/meshed distribution systems
Authors: Ataei Mohammad Ali , Gitizadeh Mohsen , Lehtonen Matti , Razavi‐Far Roozbeh 
Published: June 2021

AbstractThe complexity of the design of the protection system using directional over current relays, for modern power distribution systems has been increased due to the looped/meshed operation and the penetration of distributed generations. Finding a reliable and efficient protection scheme that can be easily implemented in these distribution systems is a major challenge. An efficient solution could be the use of artificial intelligent‐based multi‐agent systems. This paper proposes a novel distributed intelligent based multi‐agent protection scheme, which makes use of current‐only directional over current relays as agents for detecting and locating faults and isolating faulty areas (lines/busbars) in the distribution systems. All agents can make on‐board decisions by exchanging binary data, and do not need a control centre, so the safety of the protection system against one‐point failures and cyber‐attacks is increased. The proposed scheme does not need to exchange analogue data, and, therefore, it prevents the high bandwidth communication links. Moreover, it is free from the traditional coordination between relays. This scheme is implemented on the IEEE‐14 bus and IEEE‐30 bus test systems with the distributed generations and several scenarios have been simulated to evaluate its performance.
Complex eigenvalues of natural TM‐oscillations in an open resonator formed by two sinusoidally corrugated metallic strips
Authors: Vinogradova Elena D. , Kobayashi Kazuya 
Published: June 2021

AbstractThe diffraction of an E‐polarized plane wave from two finite sinusoidal gratings is investigated by a rigorous approach, based on the Method of Analytical Regularization. This allows us to analyse the problem in a wide frequency band without limitations on the depth of the sinusoidal corrugation, the wave size of the gratings, or their relative location. The homogeneous version of the equations obtained is used for accurate computation of the complex eigenvalues in an open resonator of Fabry–Perot type with sinusoidally corrugated strips. In the calculations, two types of structures were used: one is formed by parallel translation of the sinusoidally corrugated strips and the other is obtained by rotation of one of the strips in the first structure. For each relative location of the corrugated strips, the resonance excitation of the structure by an obliquely incident E‐polarized plane wave is considered. Based on the calculation of the surface current density for different incidence angles, their specific values for optimal excitation of the complex modes are established.
Flexible control for power‐sharing in the CHB‐based SST under voltage unbalance conditions
Authors: Babaei Mehdi , Ghandehari Reza 
Published: June 2021

AbstractSolid‐state transformers (SSTs) have flexible capabilities to improve the power quality issues. These improvements impose disturbances into the SST converters that require proper control algorithms. In this paper, the problems of the unequal active power flow in different phases of the SST due to the grid voltage unbalance conditions and the negative sequence current injection are discussed, and an effective method is proposed to equally sharing the active powers between the SST clusters by creating an optimum zero sequence current. Based on the power dependencies, an analytical vector for the zero‐sequence current is proposed, which can equally share the power among the SST clusters and balance the HVDC‐link voltages. Also, the proposed control strategy by using PIR controllers can achieve the zero‐sequence current based on a direct current control method. The provided equal power‐sharing among the clusters is kept in the considerable unbalanced voltage of the grid and prevents the SST outage during faults. The simulation and experimental results confirm the proposed control method to equalise the power‐sharing among the SST clusters and voltage equalisation of the HVDC‐links while the SST tries to improve the grid voltage unbalance and in the fault conditions of the grid.
JMRPE‐Net: Joint modulation recognition and parameter estimation of cognitive radar signals with a deep multitask network
Authors: Zhu Mengtao , Zhang Ziwei , Li Cong , Li Yunjie 
Published: June 2021

AbstractThe newly developed cognitive radar (CR) can implement flexible work modes defined with a set of mode definition parameters. Each definition parameter can employ its modulation type and corresponding optimised modulating values. Automatic recognition and analysis of CR work mode are significant challenges for electromagnetic reconnaissance applications. In this article, a deep multitask neural network is proposed for Joint automatic Modulation Recognition and modulation Parameter Estimation (JMRPE‐Net) for the emerging task of CR signals analysis. The proposed JMRPE‐Net consists of a fork‐shaped architecture in which three cascaded convolutional layers act as a shared module for the extraction of common features followed by multiple branches of long short‐term memory layers with the attention mechanism for task‐specific features extraction. The proposed network can receive a sequence of CR pulse signals as input and parallelly perform automatic modulation recognition (AMR) and modulation parameter estimation tasks for multiple work mode definition parameters. Extensive experiments are conducted based on simulated radar intermediate frequency signals with consideration of imperfections of real‐world electromagnetic environments. The experimental results validate the superiority of the proposed JMRPE‐Net against the existing state‐of‐the‐art single task AMR methods or parameter estimation methods.
ALMA observations of the variability of the quiet Sun at millimeter wavelengths
Authors: Nindos A. , Patsourakos S. , Alissandrakis C. E. , Bastian T. S. 
Published: June 2021

Aims. We address the variability of the quiet solar chromosphere at 1.26 mm and 3 mm with a focus on the study of spatially resolved oscillations and transient brightenings, which are small, weak events of energy release. Both phenomena may have a bearing on the heating of the chromosphere.
Methods. We used Atacama Large Millimeter/submillimeter Array (ALMA) observations of the quiet Sun at 1.26 mm and 3 mm. The spatial and temporal resolution of the data were 1 − 2″ and 1 s, respectively. The concatenation of light curves from different scans yielded a frequency resolution in spectral power of 0.5−0.6 mHz. At 1.26 mm, in addition to power spectra of the original data, we degraded the images to the spatial resolution of the 3 mm images and used fields of view that were equal in area for both data sets. The detection of transient brightenings was made after the effect of oscillations was removed.
Results. At both frequencies, we detected p-mode oscillations in the range 3.6−4.4 mHz. The corrections for spatial resolution and field of view at 1.26 mm decreased the root mean square (rms) of the oscillations by a factor of 1.6 and 1.1, respectively. In the corrected data sets, the oscillations at 1.26 mm and 3 mm showed brightness temperature fluctuations of ∼1.7 − 1.8% with respect to the average quiet Sun, corresponding to 137 and 107 K, respectively. We detected 77 transient brightenings at 1.26 mm and 115 at 3 mm. Although their majority occurred in the cell interior, the occurrence rate per unit area of the 1.26 mm events was higher than that of the 3 mm events; this conclusion does not change if we take into account differences in spatial resolution and noise levels. The energy associated with the transient brightenings ranged from 1.8 × 1023 to 1.1 × 1026 erg and from 7.2 × 1023 to 1.7 × 1026 erg for the 1.26 mm and 3 mm events, respectively. The corresponding power-law indices of the energy distribution were 1.64 and 1.73. We also found that ALMA bright network structures corresponded to dark mottles or spicules that can be seen in broadband Hα images from the GONG network.
Conclusions. The fluctuations associated with the p-mode oscillations represent a fraction of 0.55−0.68 of the full power spectrum. Their energy density at 1.26 mm is 3 × 10−2 erg cm−3. The computed low-end energy of the 1.26 mm transient brightenings is among the smallest ever reported, irrespective of the wavelength of the observation. Although the occurrence rate per unit area of the 1.26 mm transient brightenings was higher than that of the 3 mm events, their power per unit area is smaller likely due to the detection of many weak 1.26 mm events.
The practical barriers to kickstarting the innovation and investment in the sphere of construction in Russian Federation
Authors: Asaul Anatoly , Asaul Maksim , Drozdova Irina , Levin Yuri , Trushkovskaya Ekaterina 
Published: June 2021

We have identified the main issues in introducing innovation into a construction project. The solution is realized through the study of both objective and subjective obstacles to the introduction of the innovative technologies in the investment - construction cycle, which is treated as a single process, because the economic effects of innovation can be evaluated only within the full life cycle of a building. We created a highly interconnected financial model of the compounding effects of innovation in the construction industry. We present the Russian construction market’s challenges and feedback loops in innovation by using graph theory and complex analysis. The article presents the method developed in the scientific school «Methodological problems of the economic effectiveness of regional construction clusters as a self-ordering system» that shows the algorithmic consistency and transparency of evaluating the effectiveness of the innovations.
The described method can be used in a large array of scientific and theoretical tasks: from the replication of the method to other types of economic activity to the synthesis of methods and models for identifying key areas of innovation activity. It can also be used to build a method for assessing the innovative potential of a project.
Weekend and evening planned colonoscopy activity: a safe and effective way to meet demands
Authors: Afify Shimaa A. , Abo-Elazm Omnia M. , Bahbah Ishak I. , Thoufeeq Mo H. 
Published: June 2021

Abstract
Background and study aims Colonoscopy is the “gold standard” investigation for assessment of the large bowel that detects and prevents colorectal cancer, as well as non-neoplastic conditions. The Joint Advisory Group (JAG) on Gastrointestinal Endoscopy recommends monitoring key performance indicators such as cecal intubation rate (CIR) and adenoma detection rate (ADR). We aimed to investigate the quality of colonoscopies carried out during evening and Saturday lists in our unit and compare them against JAG standards of quality for colonoscopies.
Patients and methods We retrospectively collected and analyzed demographical and procedure-related data for non-screening colonoscopies performed between January 2016 and November 2018. Evenings and Saturdays were defined as the out-of-hour (OOH) period. We compared the outcomes of the procedures done in these against the working hours of the weekdays. We also wanted to explore whether the outcomes were different among certain endoscopists. Other factors that could affect the KPIs, such as endoscopist experience and bowel preparation, were also analyzed.
Results There were a total of 17634 colonoscopies carried out; 56.9 % of the patients (n = 10041) < 70 years old. Key Performance Indicators (KPIs) of weekday, evening, and Saturday colonoscopies regarding the CIR and ADR met the JAG standards as they were above 93 % and 24 %, respectively. Advanced colonoscopists had better KPIs when compared to the non-advanced colonoscopists, with CIR at 97.6 % vs. 93.2 % and ADR at 40.8 % vs. 26 %, respectively.
Conclusions JAG standards were maintained during colonoscopies done on weekdays, evenings, and Saturdays. Advanced colonoscopists had higher CIR and ADRs.
Prophylactic and Therapeutic Measures of Homeopathy in Epidemic and Pandemic Diseases
Authors: Yaseen Ghulam 
Published: June 2021

AbstractBackground The terms Epidemic and Pandemic refer to spread of infectious diseases in different countries, nations or regions. Infectious diseases have overrun millions of people in the past, as well as doing now when the world is facing current coronavirus disease 2019 (Covid-19) pandemic, which has killed more than 607,781 people till July 2020, according to the World Health Organisation. Homeopathy has played an important role in controlling epidemic and pandemic diseases distressing humanity since the time of Hahnemann who cured scarlet fever with Belladonna and served community with best treatment. This article reviews the role of homeopathy in the management and prevention of pandemic and epidemic diseases.Methods A homeopathic literature search was performed using several bibliographic databases such as Google Scholar, PubMed and Google search engine was used for collection of all relevant information from reports, review articles, archived files and Web pages etc., published in English language till July 2020.Results Gathered information based on scientific evidences manifested the efficacy of homeopathy using various approaches such as individualisation, Genus epidemicus and isopathy for prevention and treatment of epidemic diseases.Conclusion Homeopathy showcased its effectiveness in reduction of mortality and morbidity in epidemics for years. Moreover, prophylactic use of Genus epidemicus for symptomatic Covid-19 cases can be inexpensive, safe and more realistic.