bluuebunny/crossref_metadata_2025_split huggingface dataset:
Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2020 for the Clinical Practice of Hereditary Colorectal Cancer
Authors: Tomita Naohiro , Ishida Hideyuki , Tanakaya Kohji , Yamaguchi Tatsuro , Kumamoto Kensuke , Tanaka Toshiaki , Hinoi Takao , Miyakura Yasuyuki , Hasegawa Hirotoshi , Takayama Tetsuji , Ishikawa Hideki , Nakajima Takeshi , Chino Akiko , Shimodaira Hideki , Hirasawa Akira , Nakayama Yoshiko , Sekine Shigeki , Tamura Kazuo , Akagi Kiwamu , Kawasaki Yuko , Kobayashi Hirotoshi , Arai Masami , Itabashi Michio , Hashiguchi Yojiro , Sugihara Kenichi ,   Japanese Society for Cancer of the Colon, Rectum, Tomita Naohiro , Ishida Hideyuki , Tanakaya Koji , Yamaguchi Tatsuro , Kumamoto Kensuke , Tanaka Toshiaki , Hinoi Takao , Miyakura Yasuyuki , Hasegawa Hirotoshi , Ishikawa Hideki , Nakajima Takeshi , Chino Akiko , Sekine Shigeki , Tamura Kazuo , Akagi Kiwamu , Kobayashi Hirotoshi , Arai Masami , Itabashi Michio , Hashiguchi Yojiro , Sugihara Kenichi 
Published: June 2021

AbstractHereditary colorectal cancer (HCRC) accounts for < 5% of all colorectal cancer cases. Some of the unique characteristics commonly encountered in HCRC cases include early age of onset, synchronous/metachronous cancer occurrence, and multiple cancers in other organs. These characteristics necessitate different management approaches, including diagnosis, treatment or surveillance, from sporadic colorectal cancer management. There are two representative HCRC, named familial adenomatous polyposis and Lynch syndrome. Other than these two HCRC syndromes, related disorders have also been reported. Several guidelines for hereditary disorders have already been published worldwide. In Japan, the first guideline for HCRC was prepared by the Japanese Society for Cancer of the Colon and Rectum (JSCCR), published in 2012 and revised in 2016. This revised version of the guideline was immediately translated into English and published in 2017. Since then, several new findings and novel disease concepts related to HCRC have been discovered. The currently diagnosed HCRC rate in daily clinical practice is relatively low; however, this is predicted to increase in the era of cancer genomic medicine, with the advancement of cancer multi-gene panel testing or whole genome testing, among others. Under these circumstances, the JSCCR guidelines 2020 for HCRC were prepared by consensus among members of the JSCCR HCRC Guideline Committee, based on a careful review of the evidence retrieved from literature searches, and considering the medical health insurance system and actual clinical practice settings in Japan. Herein, we present the English version of the JSCCR guidelines 2020 for HCRC.
qSOFA score poorly predicts critical progression in COVID-19 patients
Authors: Heldt Sven , Neuböck Matthias , Kainzbauer Nora , Shao Guangyu , Tschoellitsch Thomas , Duenser Martin , Kaiser Bernhard , Winkler Markus , Paar Christian , Meier Jens , Lamprecht Bernd , Salzer Helmut J. F. 
Published: June 2021

Summary
Background
In December 2019, the new virus infection coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged. Simple clinical risk scores may improve the management of COVID-19 patients. Therefore, the aim of this pilot study was to evaluate the quick Sequential Organ Failure Assessment (qSOFA) score, which is well established for other diseases, as an early risk assessment tool predicting a severe course of COVID-19.

Methods
We retrospectively analyzed data from adult COVID-19 patients hospitalized between March and July 2020. A critical disease progress was defined as admission to intensive care unit (ICU) or death.

Results
Of 64 COVID-19 patients, 33% (21/64) had a critical disease progression from which 13 patients had to be transferred to ICU. The COVID-19-associated mortality rate was 20%, increasing to 39% after ICU admission. All patients without a critical progress had a qSOFA score ≤ 1 at admission. Patients with a critical progress had in only 14% (3/21) and in 20% (3/15) of cases a qSOFA score ≥ 2 at admission (p = 0.023) or when measured directly before critical progression, respectively, while 95% (20/21) of patients with critical progress had an impairment oxygen saturation (SO2) at admission time requiring oxygen supplementation.

Conclusion
A low qSOFA score cannot be used to assume short-term stable or noncritical disease status in COVID-19.
Auslander–Reiten Triangles and Grothendieck Groups of Triangulated Categories
Authors: Haugland Johanne 
Published: June 2021

AbstractWe prove that if the Auslander–Reiten triangles generate the relations for the Grothendieck group of a Hom-finite Krull–Schmidt triangulated category with a (co)generator, then the category has only finitely many isomorphism classes of indecomposable objects up to translation. This gives a triangulated converse to a theorem of Butler and Auslander–Reiten on the relations for Grothendieck groups. Our approach has applications in the context of Frobenius categories.
Prostate cancer patients’ self-reported participation in research: an examination of racial/ethnic disparities
Authors: Palmer Nynikka R. , Borno Hala T. , Gregorich Steven E. , Livaudais-Toman Jennifer , Kaplan Celia P. 
Published: June 2021

Abstract
Purpose
We examined prostate cancer patients’ participation in research and associated factors by race/ethnicity in a multiethnic sample.

Methods
Men with a new diagnosis of prostate cancer were identified through the California Cancer Registry. Patients completed a cross-sectional telephone interview in English, Spanish, Cantonese or Mandarin. Multivariable logistic regression models, stratified by race/ethnicity, estimated the associations of patient demographic and health characteristics with participation in (1) any research, (2) behavioral research, and (3) biological/clinical research.

Results
We included 855 prostate cancer patients: African American (19%), Asian American (15%), Latino (24%), and White (42%). In the overall model of participation in any research, African American men (Odds Ratio (OR) = 2.54, 95% CI 1.63–3.94), and those with two or more comorbidities (OR = 2.20, 95% CI 1.27–3.80) were more likely to report participation. Men 65 years old and older (OR = 0.65, 95% CI 0.47–0.91), those who were married or living with a partner (OR = 0.67, 95% CI 0.45–0.98), and those who completed the interview in Spanish (OR = 0.36, 95% CI 0.15–0.85) were less likely to report participating in any research. Stratified analyses identified racial/ethnic-specific sociodemographic characteristics associated with lower research participation, including Spanish or Chinese language, older age, and lower education.

Conclusion
African American prostate cancer patients reported higher research participation than all other groups. However, recruitment efforts are still needed to overcome barriers to participation for Spanish and Chinese speakers, and barriers among older adults and those with lower education levels.
Flip a coin or vote? An experiment on the implementation and efficiency of social choice mechanisms
Authors: Hoffmann Timo , Renes Sander 
Published: June 2021

AbstractCorporate boards, experts panels, parliaments, cabinets, and even nations all take important decisions as a group. Selecting an efficient decision rule to aggregate individual opinions is paramount to the decision quality of these groups. In our experiment we measure revealed preferences over and efficiency of several important decision rules. Our results show that: (1) the efficiency of the theoretically optimal rule is not as robust as simple majority voting, and efficiency rankings in the lab can differ from theory; (2) participation constraints often hinder implementation of more efficient mechanisms; (3) these constraints are relaxed if the less efficient mechanism is risky; (4) participation preferences appear to be driven by realized rather than theoretic payoffs of the decision rules. These findings highlight the difficulty of relying on theory alone to predict what mechanism is better and acceptable to the participants in practice.
Structural, optical, and electrical characterization of spray-deposited Mg0.02Zn0.98Se thin film for buffer layer application
Authors: Krishna V. S. Ganesha , Mahesha M. G. 
Published: June 2021

AbstractIn this work, spray-deposited Mg0.02Zn0.98Se thin films were characterized to determine their structural, optical, and electrical properties. The optical band gap of Mg-doped ZnSe thin film was observed to be around 3.05 eV, with high optical transmittance of about 50–70% in the visible region. The crystallite size of Mg-doped ZnSe thin film was about 8 nm, as observed from the X-ray diffraction (XRD) pattern. Elemental composition of Mg-doped ZnSe thin film was confirmed from X-ray energy-dispersive analysis (EDAS). Raman study showed the development of minor strain in ZnSe system due to the incorporation of Mg. The resistivity of the Mg-doped ZnSe film was about 3.82 ohm-m with a carrier concentration of 8.2 × 1011 cm− 3. Mg0.02Zn0.98Se thin films exhibited promising opto-electronic properties such as high transparency and conductivity that are essential for a solar buffer layer that could replace relatively toxic CdS layer.
Bystander Intervention Efficacy to Reduce Teen Dating Violence Among High School Youth Who Did and Did Not Witness Parental Partner Violence: A Path Analysis of A Cluster RCT
Authors: Mennicke Annelise , Bush Heather M. , Brancato Candace J. , Coker Ann L. 
Published: June 2021

AbstractYouth who witness parental intimate partner violence (IPV) are at increased risk of teen dating violence (DV). This analysis of secondary data investigated whether a bystander intervention program, Green Dot, was effective at reducing physical and psychological DV victimization and perpetration among youth who had and had not previously witnessed parental IPV. The parent RCT assigned 13 schools to control and 13 schools to the Green Dot intervention. Responses from 71,797 individual surveys that were completed by high school students were analyzed across three phases of a 5-year cluster randomized control trial. Multigroup path analyses revealed that students in intervention schools who witnessed parental IPV had a reduction in psychological (p < .001) and physical DV (p < .01) perpetration and psychological DV victimization (p < .01) in Phase 2 of the intervention, while those who did not witness parental IPV had a significant reduction in psychological DV victimization (p < .01). Individuals in the intervention received more training (p < .001), which was associated with lower levels of violence acceptance (p < .001). Violence acceptance was positively associated with DV victimization and perpetration (p < .001), especially for individuals who previously witnessed parental IPV. Green Dot is an effective program at reducing DV victimization and perpetration among the high-risk group of youth who previously witnessed parental IPV, largely operating through violence acceptance norms. This underscores the bystander intervention approach as both a targeted and universal prevention program.
Efficacy of physical therapy interventions on quality of life and upper quadrant pain severity in women with post-mastectomy pain syndrome: a systematic review and meta-analysis
Authors: Kannan Priya , Lam Hiu Ying , Ma Tsz Kiu , Lo Chiu Ngai , Mui Ting Yan , Tang Wing Yan 
Published: June 2021

Abstract
Purpose
To determine the efficacy of physical therapy interventions on quality of life (QoL) and pain severity in post-mastectomy pain syndrome (PMPS).

Methods
Multiple databases were searched from database inception to October 2020. Searches were limited to human studies published in either English or Chinese in peer-reviewed journals with full text available for randomized controlled trials conducted on females. Trials comparing the effectiveness of physical therapy interventions against control conditions on QoL and pain were included.

Results
Eighteen trials were included in the review. The pooled analysis of the four exercise trials revealed a significant effect of the intervention on general [standardized mean difference [SMD]: 0.87 (95%CI: 0.36, 1.37); p = 0.001], physical [SMD: 0.34 (95%CI: 0.01, 0.66); p = 0.044], and mental health components [SMD: 0.27 (95%CI: 0.03, 0.51); p = 0.027] of QoL compared with the control condition. Meta-analyses of six exercise trials, two myofascial release trials, and two acupuncture trials revealed a significant improvement in pain severity in the treatment group than in the control group. However, meta-analyses of two studies revealed a non-significant effect of compression therapy compared to control on pain severity.

Conclusion
Our meta-analyses found that exercise is beneficial for improving the QoL and pain severity of women with PMPS. Future studies are needed to determine the optimal parameters for exercise interventions designed to improve QoL and pain severity in women with PMPS. The effect of acupuncture, myofascial release, and compression therapy remains inconclusive, and future research is required to validate the effect of these interventions on PMPS.
Resonant Instability of Kink Oscillations in Magnetic Flux Tubes with Siphon Flow
Authors: Ruderman Michael S. , Petrukhin Nikolai S. 
Published: June 2021

AbstractWe study kink oscillations of a straight magnetic tube in the presence of siphon flows. The tube consists of a core and a transitional or boundary layer. The flow velocity is parallel to the tube axis, has constant magnitude, and confined in the tube core. The plasma density is constant in the tube core and it monotonically decreases in the transitional layer to its value in the surrounding plasma. We use the expression for the decrement/increment previously obtained by Ruderman and Petrukhin (Astron. Astrophys.631, A31, 2019) to study the damping and resonant instability of kink oscillations. We show that, depending on the magnitude of siphon-velocity, resonant absorption can cause either the damping of kink oscillations or their enhancement. There are two threshold velocities: When the flow velocity is below the first threshold velocity, kink oscillations damp. When the flow velocity is above the second threshold velocity, the kink oscillation amplitudes grow. Finally, when the flow velocity is between the two threshold velocities, the oscillation amplitudes do not change. We apply the theoretical result to kink oscillations of prominence threads. We show that, for particular values of thread parameters, resonant instability can excite these kink oscillations.
Causally powerful processes
Authors: Dupré John 
Published: June 2021

AbstractProcesses produce changes: rivers erode their banks and thunderstorms cause floods. If I am right that organisms are a kind of process, then the causally efficacious behaviours of organisms are also examples of processes producing change. In this paper I shall try to articulate a view of how we should think of causation within a broadly processual ontology of the living world. Specifically, I shall argue that causation, at least in a central class of cases, is the interaction of processes, that such causation is the exercise of a capacity inherent in that process and, negatively, that causation should not be understood as the instantiation of universal laws. The approach I describe has substantial similarities with the process causality articulated by Wesley Salmon and Phil Dowe for physical causation, making it plausible that the basic approach can be applied equally to the non-living world. It is an approach that builds at crucial points on the criticisms of determinism and universal causality famously articulated by Elizabeth Anscombe.
Association between psychological resilience and cognitive function in older adults: effect modification by inflammatory status
Authors: Jung Sun Jae , Lee Ga Bin , Nishimi Kristen , Chibnik Lori , Koenen Karestan C. , Kim Hyeon Chang 
Published: June 2021

AbstractTo examine the association between psychological resilience and cognitive function and investigate the role of acute inflammation as an effect modifier. Total 7535 people from the Cardiovascular and Metabolic Disease Etiology Research Center (CMERC), aged ≥ 50 years and residing in areas near Seoul, South Korea, were included in this cross-sectional analysis. Stressful life events in the past 6 months were gauged by the Life Experience Survey, and current depression symptoms were analyzed with the Beck Depression Inventory-II. Participants were categorized into the following four groups according to their past experience and depression status: reference, resilient, reactive depression, and vulnerable depression. Cognitive function was evaluated using the mini-mental state examination (MMSE). The level of high-sensitivity C-reactive protein (hsCRP) was measured from blood samples. A generalized linear model was used. Upon adjusting for socio-demographic factors, comorbidity, and lifestyle factors, the final model was stratified with the highest quartile of the hsCRP level by sex. Compared to the reference group, the resilient group showed higher MMSE, which was also significant in women (adj-β = 0.280, p-value < 0.001). Vulnerable depression group showed a significantly lower MMSE (adj-β =  − -0.997, p-value 0.002), especially in men. This pattern seemed to be limited to the low hsCRP subgroup. We provided evidence from the largest Korean population used to evaluate the association between psychological resilience and cognition, which was more prominent in low inflammatory status. Psychological resilience was associated with a lower likelihood of cognitive deficit in women. This pattern was modulated by inflammatory status.
Laminated graphene oxide membrane for recovery of mercury-containing wastewater by pervaporation
Authors: Wang Ziheng , Qin Yingzhe , Xu Xiangping , Sun Jiawei , Shen Jiancheng , Ning Xiaogang , Li Na 
Published: June 2021

AbstractMercury (Hg) is a toxic heavy metal contaminant and has very harmful effects for human health. In this work, Hg-containing wastewater with Hg concentration of 6.36 ppb and 9.4 ppb were recovered with polyethylenimine (PEI) cross-linked graphene oxide (GO) layered membrane (c-GO-PEI) by pervaporation. The influence of ionic type, the concentration of Hg and the feed temperature were investigated. The c-GO-PEI exhibited not only high rejection for salts (> 99.97%), Hg (77.5–100%) and non-purgeable organic carbon (NPOC) (67.3–90.8%) but also high flux (30.30 kg·m−2·h−1) to treat with the wastewater. In addition, the flux could be largely recovered after simple washing, indicating the excellent antifouling property of the membrane.
Identification of water use behavior and calculation of water footprint: a case study
Authors: Okutan Pelin , Akkoyunlu Atilla 
Published: June 2021

AbstractThis article adds to the literature on the investigation of water use behavior of people under their daily routines. A self-administrated survey of water users was conducted for both graduate and undergraduate students at Boğaziçi University, Turkey in 2019. This study quantifies and maps the water footprint (WF) of Boğaziçi University (BU). It reports preferences of students and personnel in terms of indoor water use, outdoor water use, and virtual water use such as transportation, shopping, and dietary preferences. Water footprints are estimated per person for both engineering students and all students of BU. WF of an average BU student is above the average WF of Turkey as well as the average global WF. The attributes that influence the water use behavior of people were broadly categorized into two groups, which were dietary preferences and shopping preferences. Moreover, the eating pattern of a person regarding whether a person consumes meat was the largest contributor to the WF of BU. The results of this study can help to develop a basic understanding of WF and how it is affected by people's choices. This study is also unique by calculating water footprint in terms of direct and virtual water footprint by considering people’s daily choices in Turkey.
Three-Dimensional Analysis of the In Vivo Motion of Implantable Cardioverter Defibrillator Leads
Authors: Szili-Torok Tamas , Rump Jens , Luther Torsten , Yap Sing-Chien 
Published: June 2021

Abstract
Better understanding of the lead curvature, movement and their spatial distribution may be beneficial in developing lead testing methods, guiding implantations and improving life expectancy of implanted leads.

Objective
The aim of this two-phase study was to develop and test a novel biplane cine-fluoroscopy-based method to evaluate input parameters for bending stress in leads based on their in vivo 3D motion using precisely determined spatial distributions of lead curvatures. Potential tensile, compressive or torque forces were not subjects of this study.

Methods
A method to measure lead curvature and curvature evolution was initially tested in a phantom study. In the second phase using this model 51 patients with implanted ICD leads were included. A biplane cine-fluoroscopy recording of the intracardiac region of the lead was performed. The lead centerline and its motion were reconstructed in 3D and used to define lead curvature and curvature changes. The maximum absolute curvature Cmax during a cardiac cycle, the maximum curvature amplitude Camp and the maximum curvature Cmax@amp at the location of Camp were calculated. These parameters can be used to characterize fatigue stress in a lead under cyclical bending.

Results
The medians of Camp and Cmax@amp were 0.18 cm−1 and 0.42 cm−1, respectively. The median location of Cmax was in the atrium whereas the median location of Camp occurred close to where the transit through the tricuspid valve can be assumed. Increased curvatures were found for higher slack grades.

Conclusion
Our results suggest that reconstruction of 3D ICD lead motion is feasible using biplane cine-fluoroscopy. Lead curvatures can be computed with high accuracy and the results can be implemented to improve lead design and testing.
Spectral properties of the logarithmic Laplacian
Authors: Laptev Ari , Weth Tobias 
Published: June 2021

AbstractWe obtain spectral inequalities and asymptotic formulae for the discrete spectrum of the operator $$\frac{1}{2}\, \log (-\Delta )$$

1
2

log

(
-
Δ
)

in an open set $$\Omega \in \mathbb R^d$$

Ω
∈

R
d

, $$d\ge 2$$

d
≥
2

, of finite measure with Dirichlet boundary conditions. We also derive some results regarding lower bounds for the eigenvalue $$\lambda _1(\Omega )$$

λ
1

(
Ω
)

and compare them with previously known inequalities.