bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Penggunaan Gagdget terhadap Kualitas Tidur Remaja: Literature Review
Authors: Nugroho Wahyu Agung , Natalya Wiwiek 
Published: December 2021

Abstract80% of the use og gadgets in Indonesia is dominated by teenagers. Teenagers can spend their time just playing with their gadgets. Meanwhile, research data show that 63% of adolescents have inadequate sleep quality. This study aimed to determine the correlation between gadget use and adolescent sleep quality using a literature review study. Using a literature review design with the PEO (population, exposure, outcame) method ang using five articles from Google Scholar, Pubmed, Proquest published in 2010-2021. It showed that most of the respondents were male (52.42%) and 13 years old (30,52%). On the use of gadgets, most respondents were in the category of low use or not addicted (71.97%). Most of the respondents also had good quality of sleep (75.30%). The five articles obtained a p-value less than 0,05. There is a correlation between the use of gadgets with adolescents sleep quality.Keywords: Adolescents; gadgets; sleep quality
AbstrakPenggunaan gadget di Indonesia 80% didominasi oleh usia remaja. Remaja bisa menghabiskan waktunya hanya untuk bermain gadget. Sedangkan data penelitian menunjukkan 63% remaja memiliki kualitas tidur kurang terpenuhi. Penelitian ini bertujuan untuk mengetahui hubungan penggunaan gadget terhadap kualitas tidur remaja menggunakan studi literature review. Menggunakan desain literature review dengan menggunakan metode PEO (population, exposure, outcame) dan menggunakan 5 artikel dari database dengan penelusuran elektronik pada Google Scholar, PubMed, Proquest yang dipublikasikan pada tahun 2010-2021. Karakteristik responden dari kelima artikel didapatkan jumlah responden terbanyak berjenis kelamin laki-laki (52,42%), responden terbanyak berusia 13 tahun (30,52). Pad penggunaan gadget sebagian besar responden pada kategori penggunaan rendah atau tidak kecanduan (71,97%) dan pada kualitas tidur sebagian besar responden memiliki kualitas yang baik (75,30%). Kelima artikel diperoleh hasil p-value < 0,05. Terdapat hubungan antara penggunaan gadget dengan kualitas tidur remaja.Kata kunci: Gadget; kualitas tidur; remaja
REHBaR: a Publication Guideline for Homeopathic Basic Research
Authors: Baumgartner Stephan , Stock-SchrÃƒÆ’Ã‚Â¶er Beate 
Published: December 2021

Background: Specific efficacy of homeopathically prepared substances in high dilution levels is controversial due to the comparably low number of randomized controlled clinical trials and due to the low concentrations of the substances potentised. No generally accepted theoretical model is currently available to explain specific effects of such preparations. In order to unequivocally demonstrate any such effects, experimental research has to meet very high standards.
Aims: Objective was to compile guidelines for homeopathic basic research regarding experimental design, implementation, execution, evaluation and publication.
Methods: A Delphi Process was conducted, involving European researchers who published experimental work within the last five years. The Delphi process included a total of five rounds, three rounds of adjusting and phrasing plus two consensus conferences [1]. Eligible criteria were collected from existing publications concerned with the quality of homeopathic basic research. In advance a short questionnaire was sent to a selection of research institutes in Germany active in non-homeopathic basic research.
Results: Regarding experimental design, the most important points to consider are: randomized and coded (blinded) allocation of the treatments, several independent experiments (including independent production lots), potentised or succussed controls, positive controls (to control reactivity of the system) and systematic negative control experiments to document test system stability and adequacy of the statistical evaluation [1ÃƒÂ¢Ã¢â€šÂ¬Ã¢â‚¬Å“4]. A detailed publication guideline for authors was developed. REHBaR (Reporting experiments in Homeopathic Basic Research) provides a checklist of 23 items, supplemented with detailed examples [4]. Background, objectives and possible hypotheses should be given in the part ÃƒÂ¢Ã¢â€šÂ¬Ã‹Å“introductionÃƒÂ¢Ã¢â€šÂ¬Ã¢â€žÂ¢. Special emphasis is put on the ÃƒÂ¢Ã¢â€šÂ¬Ã‹Å“materials and methodsÃƒÂ¢Ã¢â€šÂ¬Ã¢â€žÂ¢ section, where a detailed description of chosen controls, object of investigation, experimental setup, replication, parameters, intervention, allocation, blinding, and statistical methods is required. The section ÃƒÂ¢Ã¢â€šÂ¬Ã‹Å“resultsÃƒÂ¢Ã¢â€šÂ¬Ã¢â€žÂ¢ should present sufficient details on analyzed data, descriptive as well as inferential. Authors should discuss their results and give an interpretation in the context of current evidence.
Conclusions: Guidelines how to prepare detailed and informative publications are very common in clinical research [5]. To the best to our knowledge REHBaR is the first guideline to be applied by authors when preparing their manuscripts and to be used by scientific journals in the reviewing process in the field of homeopathic basic research. Furthermore the REHBaR guideline can be helpful for planning and conducting experiments as it includes fundamental qualitative standards. To which extent REHBAR can be used also as an instrument to evaluate the quality of a publication will be discussed.
الأنماط الاستهلاكية للألبان و منتجاتها في ولاية الخرطوم
Authors: ناهد محمد توفيق فاوي 
Published: December 2021

الأنماط الاستهلاكية للألبان و منتجاتها في ولاية الخرطوم
This research aimed at identifying the different consumption trends of the Sudanese individual in regard to fresh milk and dairy products.
It also aimed at making use of studying the behavioral consumption in the marketing field and to set a future prospectus to accomplish development and quality in dairy marketing in Sudan.
To achieve such aims a number of hypothesis were tested through analysis of data collected from families in Khartoum state different statistical methods were implemented.
Several results were concluded, of which are: 1 .Fresh milk has high acceptance among Sudanese consumers.
2.
The consumer has low trust in the quality of fresh milk sold by roaming sellers.
3.
The Sudanese consumer has low nutritional and health awareness about the value of dairy products (other than white cheese & yogurt).
The study was concluded with several recommendations, of which are: 1.
Adapting modem marketing concepts by giving more attention to consumer needs and demands and benefiting from Sudanese consumers' general food culture in the marketing procedure.
2 .
Performing marketing research on consumption patterns and habits of the Sudanese individual to benefit out of them in dairy marketing
A review on lead toxicity in Khartoum State-Sudan
Authors: Abd al-Rauf Ahmad Abbas 
Published: December 2021

A review on lead toxicity in Khartoum State-Sudan
This article is an extensive review for lead toxicity in the Sudan.
It reveals that a little has been done in this important issue in the Sudan, compared to other countries.
Some researches appear in this review, have studied lead poisoning in school children, citizens of Khartoum state, occupational districts( such as printing presses) and Lead (Pb) concentration in air, food and some Nile fish Species.
The results of this J study, indicate an elevated levels of lead in the Sudan, compared to the standard levels in other countries such as USA and Germany
One Profession-but not one Oath; a new survey revisiting the Chiropractic Oaths
Authors: Deltoff Marshall N. 
Published: December 2021

Thirty years ago, in 1988, we undertook the first formal academic examination of the Chiropractic Oath: its development and an analysis of its component parts. At that time, we studied 38 oaths from 25 different chiropractic colleges. Various themes and topics were identified, some of which occurred consistently, and others appearing but once or twice. With the recent global expansion of our profession to new schools in many more countries, the oaths presently used at chiropractic colleges worldwide were subjected to the same analysis for comparison. 42 oaths were obtained from the 45 institutions currently listed on the World Federation of Chiropractic website. Increased access, both electronically and in person, has enabled our academic institutions to communicate and relate at a level unimaginable thirty years ago. This increasing college interaction is one aspect of our progressive unity. It is proposed that consideration be given to the development of a single Chiropractic Oath as a tangible example of this professional unity.
Het vervangen van de zekerhedenagent
Authors: Kreuze G. , Broere M. 
Published: December 2021

Het vervangen van de zekerhedenagent. De parallel debt revisited
In dit artikel bespreken de auteurs de aandachtspunten die spelen bij een vervanging van de zekerhedenagent onder bijzondere titel aan de hand van een syndicaatslening gedocumenteerd op basis van de modellen van de Loan Market Association en gesecureerd door Nederlandsrechtelijke zekerheden. Ter achtergrond komen de volgende onderwerpen aan bod: (a) de invulling van de rol van zekerhedenagent en (b) het vervangen van de zekerhedenagent. Het zwaartepunt van dit artikel ligt op een vervanging van de zekerhedenagent onder bijzondere titel naar Nederlands recht, maar nu bij toe- en uittreding van de zekerhedenagent vaak Engels recht wordt toegepast, hebben we ervoor gekozen om in dit artikel ook aandacht te besteden aan de Engelse trust en een aantal Engelsrechtelijke aspecten van de overgang van de parallel debt en de daarvoor gevestigde Nederlandsrechtelijke zekerheden.
¿Masculinidades en tránsito? Viejas y nuevas formas de ser hombre a través de la mirada de Ramón Pérez de Ayala
Authors: Mira Abad Alicia , Lillo Gutiérrez Berta 
Published: December 2021

Este trabajo se centra en el análisis de los discursos sobre la modernización de la España del primer tercio del siglo XX, a través de la mirada del escritor Ramón Pérez de Ayala y su obra publicada en 1926 Tigre Juan y El Curandero de su honra, en la que aborda la transformación del modelo de masculinidad tradicional. Aunque en los discursos de la época se apela a una necesaria remasculinización, continúan perviviendo ideales de virilidad atávicos. Así que, más que la ruptura o la emergencia de un nuevo modelo de hombría, debería hablarse de la coexistencia de elementos nuevos y viejos. Pérez de Ayala y la generación de intelectuales que le acompañan conciben este cambio como el primer paso para que el país pueda salir de su inmovilismo, aunque no cuestionan los principios básicos de la sociedad patriarcal, ya que la nación se sigue concibiendo como un espacio masculino. Los integrantes de la llamada Generación del 14 se sitúan frente al pesimismo nihilista de entresiglos mostrando un claro compromiso político fundamentado en la razón, alineándose con el proyecto liberal, la democracia y en la mayor parte de los casos con el republicanismo. En sus obras, y especialmente en el texto que constituye nuestro objeto de atención, se diagnostican los problemas de España desde la perspectiva de la masculinidad y la búsqueda de un modelo de hombría acorde con un país moderno y europeo.
A journey through theCorynebacterium pseudotuberculosisproteome promotes insights into its functional genome
Authors: Marques da Silva Wanderson , Seyffert Nubia , Silva Artur , Azevedo Vasco 
Published: December 2021

BackgroundCorynebacterium pseudotuberculosisis a Gram-positive facultative intracellular pathogen and the etiologic agent of illnesses like caseous lymphadenitis in small ruminants, mastitis in dairy cattle, ulcerative lymphangitis in equines, and oedematous skin disease in buffalos. With the growing advance in high-throughput technologies, genomic studies have been carried out to explore the molecular basis of its virulence and pathogenicity. However, data large-scale functional genomics studies are necessary to complement genomics data and better understating the molecular basis of a given organism. Here we summarize, MS-based proteomics techniques and bioinformatics tools incorporated in genomic functional studies ofC. pseudotuberculosisto discover the different patterns of protein modulation under distinct environmental conditions, and antigenic and drugs targets.MethodologyIn this study we performed an extensive search in Web of Science of original and relevant articles related to methods, strategy, technology, approaches, and bioinformatics tools focused on the functional study of the genome ofC. pseudotuberculosisat the protein level.ResultsHere, we highlight the use of proteomics for understating several aspects of the physiology and pathogenesis ofC. pseudotuberculosisat the protein level. The implementation and use of protocols, strategies, and proteomics approach to characterize the different subcellular fractions of the proteome of this pathogen. In addition, we have discussed the immunoproteomics, immunoinformatics and genetic tools employed to identify targets for immunoassays, drugs, and vaccines againstC. pseudotuberculosisinfection.ConclusionIn this review, we showed that the combination of proteomics and bioinformatics studies is a suitable strategy to elucidate the functional aspects of theC. pseudotuberculosisgenome. Together, all information generated from these proteomics studies allowed expanding our knowledge about factors related to the pathophysiology of this pathogen.
An Observational Study on Coping and Quality of Life among Perimenopausal Women
Authors: Jayamalli N. , Priya D. Joanie , Sailatha . 
Published: December 2021

Background: Perimenopause is a natural phenomenon signaling the reduction of ovarian function. Worldwide, the age at which natural menopause occurs is between 45 to55 years. Many women during the premenopausal age group may experience menopausal symptoms such as physiological changes, psychological changes, urogenital changes, sexual changes and vasomotor changes. These changes and symptoms the women may have negative impact on Quality of Life among perimenopausal women. The main aim of the study was to assess the coping and quality of life among perimenopausal women.
Materials and Methods: The researcher has used a quantitative research approach and convenient sampling technique was adapted to select 165 perimenopausal women with the age group of 40 to 55 years. Researcher assessed the perimenopausal symptoms, observed the coping and quality of life among perimenopausal women by Greene climacteric scales, modified cope inventory scale and Utian quality of life scale respectively. The study was conducted in Poonjeri, Kadampadi, and Perumalari villages from Chengalpattu District, for the period of four weeks.
Results: There was a positive correlation between cope and quality of life among perimenopausal women. There is no association was observed between the monthly income and quality of life of the perimenopausal women, as the Chi-square test was statistically significant at p<0.05.
Conclusion: The study concludes that the perimenopausal women who are participated in this study have moderate symptoms, moderate coping, and moderate quality of life. The monthly income was effective in influencing the perimenopausal women’s quality of life.
Mesenchymal Stem Cell Exosomes and Cancer: Controversies and Prospects
Authors: Yassine Sirine , Alaaeddine Nada 
Published: December 2021

AbstractMesenchymal stem cells (MSCs) have displayed a novel therapeutic strategy for a wide range of diseases and conditions. Their secretome and exosome‐based paracrine activity are considered as the main processes harboring their diverse therapeutic properties. Several investigations have examined the effects of MSC‐derived exosomes on cancer growth, yet, controversial results have always emerged. Although MSC‐derived exosomes are able to rigorously enforce the repression of cancer proliferation and progression, it is shown that MSCs exosomal activity displays numerous protumorigenic effects. This discrepancy over the dual effects of MSCs on cancer growth may be mediated by many factors including experimental design, stem cells origins, culture conditions, in addition to cancer‐MSCs cross‐talks. Despite the controversial effects of MSCs on carcinogenesis, scientists are able to overcome a number of obstacles by modifying MSCs to deliver antioncogenic miRNAs, anticancer drugs, and oncolytic viruses into tumor sites. This review discusses the controversial effects of MSC‐derived exosomes on tumorigenesis, investigates the main causes that underlie this discrepancy, summarizes the pattern of engineered‐MSCs, and finally highlights how future studies should advance the research in the field of MSCs‐based cancer therapies in order to accelerate the transition from preclinical studies to clinical practice.
Single‐Cell Sequencing to Unveil the Mystery of Embryonic Development
Authors: Li Zida , Lin Feng , Zhong Chu‐Han , Wang Shue , Xue Xufeng , Shao Yue 
Published: December 2021

AbstractEmbryonic development is a fundamental physiological process that can provide tremendous insights into stem cell biology and regenerative medicine. In this process, cell fate decision is highly heterogeneous and dynamic, and investigations at the single‐cell level can greatly facilitate the understanding of the molecular roadmap of embryonic development. Rapid advances in the technology of single‐cell sequencing offer a perfectly useful tool to fulfill this purpose. Despite its great promise, single‐cell sequencing is highly interdisciplinary, and successful applications in specific biological contexts require a general understanding of its diversity as well as the advantage versus limitations for each of its variants. Here, the technological principles of single‐cell sequencing are consolidated and its applications in the study of embryonic development are summarized. First, the technology basics are presented and the available tools for each step including cell isolation, library construction, sequencing, and data analysis are discussed. Then, the works that employed single‐cell sequencing are reviewed to investigate the specific processes of embryonic development, including preimplantation, peri‐implantation, gastrulation, and organogenesis. Further, insights are provided on existing challenges and future research directions.
Nanostructured Materials and Architectures for Advanced Optoelectronic Synaptic Devices
Authors: Ilyas Nasir , Wang Jinyong , Li Chunmei , Li Dongyang , Fu Hao , Gu Deen , Jiang Xiangdong , Liu Fucai , Jiang Yadong , Li Wei 
Published: December 2021

AbstractNeuromorphic photonics system based on the principle of biological brain is emerging as one of the potential solutions to the bottleneck inherent in classical von Neumann computing system. Optoelectronic synaptic devices, used to mimic the visual function of bio‐synapse by adapting synaptic weights, can construct a highly efficient brain‐inspired computing system, in which the nanostructured materials and device architectures are attracting extensive interests, giving many potential benefits in confined light‐matter interaction, fast carrier dynamics, and photocarriers trapping. Moreover, the conjunction of traditional nanostructured photodetectors and newly realized electronic synapses also exhibit appealing performance for many practical applications including information processing and computing. This review focuses and summarizes on recent achievement in developing advanced optoelectronic synaptic devices based on nanostructured materials as 0D (quantum dots), 1D, and 2D materials, as well as, the rapidly evolving hybrid heterostructures. In addition, challenges and promising prospects in this research field are also discussed.
Thermal Diodes Based on Fractal Structures with Tunable Thermal Threshold
Authors: Li Tian , Jiang Weitao , Zhang Yue , Li Baotong , Wang Lanlan , Niu Dong , Liu Hongzhong , Yin Lei , Shi Yongsheng , Chen Bangdao , Chen Jinju , Liu Xiaokang , Peng Donglin 
Published: December 2021

AbstractThe asymmetry of heat conduction in thermal diodes is attributed to the thermal regulation in thermal logic circuits, thermal control devices, etc. Currently, thermal rectification devices, however, are constrained by either specific on/off switching thresholds, or low sensitivity to manufacturing errors, as well as the restrictions for specific roughness and material characteristics. Here, a thermal diode based on fractal structures (inverted tapered branch channel, 5.7 mm branch length, and 4 branches) with liquid metal/insulator interface is proposed to avoid these existing constraints. The thermal rectification coefficient reaches 0.4704 (16.43 times larger than that of the basic structures) when the filling fraction only increases 1.33 times. The maximum temperature difference for the optimized thermal diodes is 18.31 °C when the heating temperature is 80 °C. By different arrangements of two thermal diodes mounted on chambers’ surfaces, the interior temperatures range from 16.06 to 52.34 °C in the same ambient conditions (23.49 °C), indicating the excellent thermal regulation effect of the thermal diodes. These controlled temperature chambers can be applied in greenhouses or cold chain storage devices, more combinations with higher degree of thermal‐threshold tunability offer possibilities in solving complicated thermal management problems and promote the energy utilization efficiency.
Hive‐Inspired Multifunctional Wood‐Nanotechnology‐Derived Membranes with a Double‐Layer Conductive Network Structure for Flexible Electronics
Authors: Zhang Weiye , Wang Beibei , Sun Jingmeng , Li Yanchen , Zhao Junqi , Liu Yi , Guo Hongwu 
Published: December 2021

AbstractNext‐generation flexible electronics must achieve multifunctionality, environmental friendliness and antibacterial activity. Accordingly, organisms in nature are interconnected. Inspired by the honeycomb multilayer porous structure, a wood‐nanotechnology‐derived flexible membrane circuit is created to meet the abovementioned requirements. The flexible wood (FW) matrix is made of natural balsa wood that underwent a simple top‐down chemical treatment. The multiwalled carbon nanotube (MWCNT) acts as a “bridge” between the FW matrix with a porous array structure and the active material (silver nanoparticles (Ag NPs) and poly(3,4‐ethylenedioxythiophene)‐poly(styrenesulfonate) (PEDOT:PSS). Due to the three‐dimensional porous microstructure and highly conductive surface inherited by the wood‐nanotechnology‐derived flexible membrane (FW/MWCNT/Ag/PEDOT:PSS), it shows a high area capacitance (266.7 mF cm−2 at 20 mV s−1) and a good long‐term cycling stability 84.3% capacitance retention after 5000 cycles at 5 mA cm−2 when used as a supercapacitor electrode. In addition, it shows an excellent specific electromagnetic shielding efficiency (up to 970 dB cm2 g−1), proving its application potential in the field of electromagnetic shielding. Because of the biocidal property of Ag NPs, the FW/MWCNT/Ag/PEDOT:PSS shows a remarkable antibacterial effect on Escherichia coli and Staphylococcus aureus. This strategy provides a new opportunity for researchers to design biomass‐based integrated electronic materials.