bluuebunny/crossref_metadata_2025_split huggingface dataset:
Educators’ experiences with governance in curriculum change processes; a qualitative study using rich pictures
Authors: Velthuis Floor , Dekker Hanke , Coppoolse Remco , Helmich Esther , Jaarsma Debbie 
Published: March 2021

AbstractIn the midst of continuous health professions curriculum reforms, critical questions arise about the extent to which conceptual ideas are actually put into practice. Curricula are often not implemented as intended. An under-explored aspect that might play a role is governance. In light of major curriculum changes, we explored educators’ perspectives of the role of governance in the process of translating curriculum goals and concepts into institutionalized curriculum change at micro-level (teacher–student). In three Dutch medical schools, 19 educators with a dual role (teacher and coordinator) were interviewed between March and May 2018, using the rich pictures method. We employed qualitative content analysis with inductive coding. Data collection occurred concurrently with data analysis. Different governance processes were mentioned, each with its own effects on the curriculum and organizational responses. In Institute 1, participants described an unclear governance structure, resulting in implementation chaos in which an abstract educational concept could not be fully realized. In Institute 2, participants described a top–down and strict governance structure contributing to relatively successful implementation of the educational concept. However it also led to demotivation of educators, who started rebelling to recover their perceived loss of freedom. In Institute 3, participants described a relatively fragmentized process granting a lot of freedom, which contributed to contentment and motivation but did not fully produce the intended changes. Our paper empirically illustrates the importance of governance in curriculum change. To advance curriculum change processes and improve their desired outcomes it seems important to define and explicate both hard and soft governance processes.
The living fossil concept: reply to Turner
Authors: Lidgard Scott , Love Alan C. 
Published: March 2021

AbstractDespite the iconic roles of coelacanths, cycads, tadpole shrimps, and tuataras as taxa that demonstrate a pattern of morphological stability over geological time, their status as living fossils is contested. We responded to these controversies with a recommendation to rethink the function of the living fossil concept (Lidgard and Love in Bioscience 68:760–770, 2018). Concepts in science do useful work beyond categorizing particular items and we argued that the diverse and sometimes conflicting criteria associated with categorizing items as living fossils represent a complex problem space associated with answering a range of questions related to prolonged evolutionary stasis. Turner (Biol Philos 34:23, 2019) defends the living concept against a variety of recent skeptics, but his criticism of our approach relies on a misreading of our main argument. This misreading is instructive because it brings into view the value of three central themes for rethinking the living fossil concept—the function of concepts in biology outside of categorization, the methodological importance of distinguishing parts and wholes in conceptualizing evolutionary phenomena, and articulating diverse explanatory goals associated with these phenomena.
Digital well-being under pandemic conditions: catalysing a theory of online flourishing
Authors: Dennis Matthew J. 
Published: March 2021

AbstractThe COVID-19 pandemic has catalysed what may soon become a permanent digital transition in the domains of work, education, medicine, and leisure. This transition has also precipitated a spike in concern regarding our digital well-being. Prominent lobbying groups, such as the Center for Humane Technology (CHT), have responded to this concern. In April 2020, the CHT has offered a set of ‘Digital Well-Being Guidelines during the COVID-19 Pandemic.’ These guidelines offer a rule-based approach to digital well-being, one which aims to mitigate the effects of moving much of our lives online. The CHT’s guidelines follow much recent interest in digital well-being in the last decade. Ethicists of technology have recently argued that character-based strategies and redesigning of online architecture have the potential to promote the digital well-being of online technology users. In this article, I evaluate (1) the CHT’s rule-based approach, comparing it with (2) character-based strategies and (3) approaches to redesigning online architecture. I argue that all these approaches have some merit, but that each needs to contribute to an integrated approach to digital well-being in order to surmount the challenges of a post-COVID world in which we may well spend much of our lives online.
Offshore wind farms and the attraction–production hypothesis: insights from a combination of stomach content and stable isotope analyses
Authors: Mavraki Ninon , Degraer Steven , Vanaverbeke Jan 
Published: March 2021

AbstractOffshore wind farms (OWFs) act as artificial reefs, attracting high abundances of fish, which could potentially increase their local production. This study investigates the feeding ecology of fish species that abundantly occur at artificial habitats, such as OWFs, by examining the short- and the long-term dietary composition of five species: the benthopelagicGadus morhuaandTrisopterus luscus, the pelagicScomber scombrusandTrachurus trachurus, and the benthicMyoxocephalus scorpioides. We conducted combined stomach content and stable isotope analyses to examine the short- and the time-integrated dietary composition, respectively. Our results indicated that benthopelagic and benthic species utilize artificial reefs, such as OWFs, as feeding grounds for a prolonged period, since both analyses indicated that they exploit fouling organisms occurring exclusively on artificial hard substrates.Trachurus trachurusonly occasionally uses artificial reefs as oases of highly abundant resources.Scomber scombrusdoes not feed on fouling fauna and therefore its augmented presence in OWFs is probably related to reasons other than the enhanced food availability. The long-termed feeding preferences of benthic and benthopelagic species contribute to the hypothesis that the artificial reefs of OWFs could potentially increase the fish production in the area. However, this was not supported for the pelagic species.
Targeted genome editing of plants and plant cells for biomanufacturing
Authors: Buyel J. F. , Stöger E. , Bortesi L. 
Published: March 2021

AbstractPlants have provided humans with useful products since antiquity, but in the last 30 years they have also been developed as production platforms for small molecules and recombinant proteins. This initially niche area has blossomed with the growth of the global bioeconomy, and now includes chemical building blocks, polymers and renewable energy. All these applications can be described as “plant molecular farming” (PMF). Despite its potential to increase the sustainability of biologics manufacturing, PMF has yet to be embraced broadly by industry. This reflects a combination of regulatory uncertainty, limited information on process cost structures, and the absence of trained staff and suitable manufacturing capacity. However, the limited adaptation of plants and plant cells to the requirements of industry-scale manufacturing is an equally important hurdle. For example, the targeted genetic manipulation of yeast has been common practice since the 1980s, whereas reliable site-directed mutagenesis in most plants has only become available with the advent of CRISPR/Cas9 and similar genome editing technologies since around 2010. Here we summarize the applications of new genetic engineering technologies to improve plants as biomanufacturing platforms. We start by identifying current bottlenecks in manufacturing, then illustrate the progress that has already been made and discuss the potential for improvement at the molecular, cellular and organism levels. We discuss the effects of metabolic optimization, adaptation of the endomembrane system, modified glycosylation profiles, programmable growth and senescence, protease inactivation, and the expression of enzymes that promote biodegradation. We outline strategies to achieve these modifications by targeted gene modification, considering case-by-case examples of individual improvements and the combined modifications needed to generate a new general-purpose “chassis” for PMF.
Delayed Teleoperation with Force Feedback of a Humanoid Robot
Authors: Moya Viviana , Slawiñski Emanuel , Mut Vicente 
Published: March 2021

AbstractTeleoperation systems allow the extension of human capabilities to remote-control devices by providing the operator with conditions similar to those at the remote site through a communication channel that sends information from one site to the other. This article aims to present an analysis of the benefits of force feedback applied to the bilateral teleoperation of a humanoid robot with time-varying delay. As a control scheme, we link adaptive inverse dynamics compensation, balance control, and P+d like controllers. Finally, a test is performed where an operator simultaneously handles the locomotion (forward velocity and turn angle) and arm of a simulated 3D humanoid robot to do a pick-and-place task using two master devices with force feedback, where indexes such as time to complete the task, coordination errors, path tracking error, and percentage of successful tests are reported for different time-delays. We conclude with the results achieved.
Lung ultrasound presentation of COVID-19 patients: phenotypes and correlations
Authors: Secco Gianmarco , Delorenzo Marzia , Salinaro Francesco , Zattera Caterina , Barcella Bruno , Resta Flavia , Sabena Anna , Vezzoni Giulia , Bonzano Marco , Briganti Federica , Cappa Giovanni , Zugnoni Francesca , Demitry Lorenzo , Mojoli Francesco , Baldanti Fausto , Bruno Raffaele , Perlini Stefano ,   The GERICO (Gruppo Esteso RIcerca COronarovirus) Lung US Pavia Study Group, Martino Ilaria , Guglielmana Barbarah , Zunino Ilaria , Quaglia Federica , Pettenazza Pietro , di Marco Serena Pioli , Briganti Domenica Federica , Falchi Anna Giulia , Alfano Claudia , Mossolani Elisa , Sciarrini Massimiliano , Zattera Caterina , Maisak Igor , Tassi Michele , Galati Stefano , Capozza  , Melara Ilaria , Chiodi Benedetta , Vignaroli Damiano , Scattaglia Lorenzo , Bissichini Giulia , Bazzini Marco 
Published: March 2021

AbstractBedside lung ultrasound (LUS) can play a role in the setting of the SarsCoV2 pneumonia pandemic. To evaluate the clinical and LUS features of COVID-19 in the ED and their potential prognostic role, a cohort of laboratory-confirmed COVID-19 patients underwent LUS upon admission in the ED. LUS score was derived from 12 fields. A prevalent LUS pattern was assigned depending on the presence of interstitial syndrome only (Interstitial Pattern), or evidence of subpleural consolidations in at least two fields (Consolidation Pattern). The endpoint was 30-day mortality. The relationship between hemogasanalysis parameters and LUS score was also evaluated. Out of 312 patients, only 36 (11.5%) did not present lung involvment, as defined by LUS score < 1. The majority of patients were admitted either in a general ward (53.8%) or in intensive care unit (9.6%), whereas 106 patients (33.9%) were discharged from the ED. In-hospital mortality was 25.3%, and 30-day survival was 67.6%. A LUS score > 13 had a 77.2% sensitivity and a 71.5% specificity (AUC 0.814; p < 0.001) in predicting mortality. LUS alterations were more frequent (64%) in the posterior lower fields. LUS score was related with P/F (R2 0.68; p < 0.0001) and P/F at FiO2 = 21% (R2 0.59; p < 0.0001). The correlation between LUS score and P/F was not influenced by the prevalent ultrasound pattern. LUS represents an effective tool in both defining diagnosis and stratifying prognosis of COVID-19 pneumonia. The correlation between LUS and hemogasanalysis parameters underscores its role in evaluating lung structure and function.
A virtual commissioning based methodology to integrate digital twins into manufacturing systems
Authors: Barbieri Giacomo , Bertuzzi Alberto , Capriotti Andrea , Ragazzini Lorenzo , Gutierrez David , Negri Elisa , Fumagalli Luca 
Published: March 2021

AbstractDigital Twin (DT) is considered a key approach to enhance the system reactivity to uncertain events due to its ability to getting data from the field and triggering actions on the physical asset. Given the modern technological and rapidly changing work environment, it is likely that in the next years companies will need to retrofit their manufacturing systems by integrating DTs. In this context, it is fundamental to define the necessary steps for the development of DTs and for their integration into manufacturing systems through a DT architecture. In response to this issue, a methodology based on Virtual Commissioning is proposed. A stepwise approach is illustrated in which the DT is designed, integrated and verified using a virtual environment. The methodology is validated through the integration of a DT into a flow shop for the implementation of a scheduling reactive to machine breakdown. By following the steps of the proposed methodology, a DT architecture able to improve the makespan of the studied flow shop is developed, suggesting the potential applicability of the approach to industrial manufacturing systems.
Sex and Relationship Differences on the Short Love Attitude Scale: Insights from the Hungarian Adaptation
Authors: Meskó Norbert , Zsidó András N. , Láng András , Karádi Kázmér 
Published: March 2021

AbstractLove styles are attitudes towards romantic relationships that are related to sexual motivation, sociosexuality, mate value, and relationship status. In the present study, the Short Love Attitude Scale (LAS-SF) was adapted to Hungarian, and the original factor structure was replicated with a Hungarian sample of 800 participants (439 females, mean age = 38.6 years). The results show that the Hungarian LAS-SF is a reliable and valid measure, which enables cross-cultural comparisons. Differences in love styles were revealed across sexes and relationship statuses. All men except singles scored relatively high on Eros, while the highest Eros scores among women were obtained for those in a committed relationship. Women and men preferred the same strategy (Ludus) to achieve short-term relationship goals.
A partial skeleton of a new species of Tynskya Mayr, 2000 (Aves, Messelasturidae) from the London Clay highlights the osteological distinctness of a poorly known early Eocene “owl/parrot mosaic”
Authors: Mayr Gerald 
Published: March 2021

AbstractTynskya eocaena is an early Eocene bird with a raptor-like skull and semi-zygodactyl feet, whose description is based on a skeleton from the North American Green River Formation. In the present study, three-dimensionally preserved bones of a new species of Tynskya, T. waltonensis, are reported from the London Clay of Walton-on-the-Naze (Essex, UK). The fossils belong to a single individual and provide new insights into the skeletal morphology of messelasturids. In particular, they reveal unusual vertebral specializations, with the cervical vertebrae having concave rather than saddle-shaped caudal articulation facets and the caudalmost thoracic vertebra being platycoelous (flat articular surfaces). The very deep mandible and a derived morphology of the ungual phalanges support a sister group relationship between Tynskya and the taxon Messelastur (Messelasturidae). Phylogenetic analyses of an emended data matrix did not conclusively resolve the higher-level affinities of messelasturids and the closely related halcyornithids, with both taxa sharing derived characters with only distantly related extant taxa (Accipitriformes, Strigiformes, Falconiformes, and Psittaciformes). An analysis that was constrained to a molecular scaffold, however, recovered messelasturids as the sister taxon of a clade including psittaciform and passeriform birds. The derived morphologies of the mandible and cervical vertebrae suggest specialized feeding adaptations of Tynskya, and messelasturids may have exploited a feeding niche, which is no longer available to extant birds.
Regional groundwater flow and karst evolution–theoretical approach and example from Switzerland
Authors: Scheidler Stefan , Huggenberger Peter , Dresmann Horst , Auckenthaler Adrian , Epting Jannis 
Published: March 2021

AbstractIn regional scale aquifers in the Rhine Valley and Tabular Jura east of Basel (Switzerland), the groundwater circulation was investigated using regional-scale geological and hydraulic 3D models. The main aquifers in the area comprise the Quaternary aquifer of unconsolidated gravel deposits along the River Rhine and its tributaries, as well as the regional scale karst aquifer within the Upper Muschelkalk. Land subsidence, a process likely associated with salt solution mining, indicates further subordinate groundwater bearing segments and complex groundwater interactions along fault zones. In the aquifer systems we investigated, regional-scale groundwater circulation was simulated and visualized in relation to the geological settings. Lithostratigraphic units and fault structures were parameterized and analyzed, including the sensitivity of hydraulic properties and boundaries. Scenario calculations were used to investigate the sensitivity that the aquifer systems had to hydraulic parameter changes during Quaternary aggradation and degradation in the main valley. Those calculations were also done for base-level changes in the Rivers Rhine and Birs. For this purpose, this study considered probable historic base-levels before river regulation occurred, and before river dams and power plants were constructed. We also focused on scenarios considering increased groundwater recharge rates, e.g. due to exceptional long-lasting precipitation, or heavy rainfall events in the catchment area. Our results indicate that increased groundwater recharge rates in the catchment areas during such events (or periods) are associated with orders of magnitude increases of regional inflow into the Upper Muschelkalk karst aquifer. Furthermore, the groundwater fluctuations and groundwater saturated regions within the karst aquifer shift to places where high densities of sinkholes are documented. When the surface water base-levels adapt to probable historic levels, it leads to increased hydraulic gradients (i.e. local lowering of the groundwater level by up to 7 m). Those increased gradients are associated with increased groundwater flow within some aquifer regions that are particularly prone to karst development.
A systematic evaluation of assumptions in centrality measures by empirical flow data
Authors: Bockholt Mareike , Zweig Katharina A. 
Published: March 2021

AbstractWhen considering complex systems, identifying the most important actors is often of relevance. When the system is modeled as a network, centrality measures are used which assign each node a value due to its position in the network. It is often disregarded that they implicitly assume a network process flowing through a network, and also make assumptions of how the network process flows through the network. A node is then central with respect to this network process (Borgatti in Soc Netw 27(1):55–71, 2005, 10.1016/j.socnet.2004.11.008). It has been shown that real-world processes often do not fulfill these assumptions (Bockholt and Zweig, in Complex networks and their applications VIII, Springer, Cham, 2019, 10.1007/978-3-030-36683-4_7). In this work, we systematically investigate the impact of the measures’ assumptions by using four datasets of real-world processes. In order to do so, we introduce several variants of the betweenness and closeness centrality which, for each assumption, use either the assumed process model or the behavior of the real-world process. The results are twofold: on the one hand, for all measure variants and almost all datasets, we find that, in general, the standard centrality measures are quite robust against deviations in their process model. On the other hand, we observe a large variation of ranking positions of single nodes, even among the nodes ranked high by the standard measures. This has implications for the interpretability of results of those centrality measures. Since a mismatch of the behaviour of the real network process and the assumed process model does even affect the highly-ranked nodes, resulting rankings need to be interpreted with care.
Hydrous cerium oxides coated glass fiber for efficient and long-lasting arsenic removal from drinking water
Authors: Li Ronghui , Yang Weiyi , Gao Shuang , Shang Jianku , Li Qi 
Published: March 2021

AbstractA novel arsenic adsorbent with hydrous cerium oxides coated on glass fiber cloth (HCO/GFC) was synthesized. The HCO/GFC adsorbents were rolled into a cartridge for arsenic removal test. Due to the large pores between the glass fibers, the arsenic polluted water can flow through easily. The arsenic removal performance was evaluated by testing the equilibrium adsorption isotherm, adsorption kinetics, and packed-bed operation. The pH effects on arsenic removal were conducted. The test results show that HCO/GFC filter has high As(V) and As(III) removal capacity even at low equilibrium concentration. The more toxic As(III) in water can be easily removed within a wide range of solution pH without pre-treatment. Arsenic contaminated ground-water from Yangzong Lake (China) was used in the column test. At typical breakthrough conditions (the empty bed contact time, EBCT = 2 min), arsenic researched breakthrough at over 24,000 bed volumes (World Health Organization (WHO) suggested that the maximum contaminant level (MCL) for arsenic in drinking water is 10 mg/L). The Ce content in the treated water was lower than 5 ppb during the column test, which showed that cerium did not leach from the HCO/GFC material into the treated water. The relationship between dosage of adsorbents and the adsorption kinetic model was also clarified, which suggested that the pseudo second order model could fit the kinetic experimental data better when the adsorbent loading was relatively low, and the pseudo first order model could fit the kinetic experimental data better when the adsorbent loading amount was relatively high.