bluuebunny/crossref_metadata_2025_split huggingface dataset:
Growth hormone deficiency in a child with benign hereditary chorea caused by a de novo mutation of the TITF1/NKX2-1 gene
Authors: Trevisani Viola , Predieri Barbara , Madeo Simona Filomena , Fusco Carlo , Garavelli Livia , Caraffi Stefano , Iughetti Lorenzo 
Published: October 2021

Abstract

Objectives
Benign Hereditary Chorea (BHC) (MIM 118700) is a rare childhood-onset movements disorder characterized by non-progressive chorea. It is usually caused by variants in the thyroid transcription factor 1 (TITF-1/NKX2-1) gene and it is associated with thyroid dysfunction and pulmonary symptoms in the brain–lung–thyroid syndrome.

Case presentation
We reported the clinical case of a toddler presenting with neurological symptoms (hypotonia, delayed motor milestones, and axial dystonia) and subclinical hypothyroidism in which we found a ‘de novo’ variant in the NKX2-1 gene.

Conclusions
The peculiarity of our case is that the mild alteration of thyroid-stimulating hormone (TSH) levels, hypotonia, and delayed motor milestones were associated with growth hormone deficiency.
The crystal structure of catena-poly[(1,10-phenanthroline-k2
N,N′)-(μ3-tetraoxidomoybdato(VI)-k3
O:O′:O″)manganese(II)] C12H8N2O4MoMn
Authors: Ze-Hai Qiu , Zhu-Sen Zhang , Wu-Hua Chen 
Published: October 2021

Abstract
C12H8N2O4MoMn, monoclinic, P21/m (no. 11), a = 8.9812(5) Å, b = 6.5212(3) Å, c = 10.6167(6) Å, β = 100.120(6)°, V = 612.13(6) Å3, Z = 2, R

gt
(F) = 0.0391, wR
ref(F
2) = 0.0783, T = 293(2) K.
Laser irradiation effects on structural, morphological and mechanical characteristics of iron
Authors: Shahid Wajeehah , Shahid Samiah , Iqbal Muhammad Aamir , Idrees Faryal , Ud Din Syed Zaheer , Shah Atta Ullah , Alam Khan , Kanwal Qudsia , Iqbal Sadia Sagar 
Published: October 2021

Abstract
This study is aimed to investigate laser irradiation effects on the surface, structural, and mechanical properties of iron samples. The prepared samples have been treated for multiple exposure times using continuous-wave diode laser with a wavelength of 532 nm in a laboratory environment. The structural as well as surface modifications of laser exposed targets are explored via scanning electron microscope and X-ray diffractometer. The SEM analysis revealed micrometer grain size, exfoliational sputtering, and crater formation, while XRD patterns were used to investigate d-spacing, and grain size of laser exposed samples. The mechanical characteristics of laser-ablated materials were examined using a micro Vickers hardness-tester, and microhardness has been explored as a function of increasing laser exposure time. It has been observed that grain size reduces while hardness of polycrystalline iron increases with increase in exposure time.
Overview of early childhood care and education in Malaysia
Authors: Rahmatullah Bahbibi , Muhamad Rawai Norshakila , Mohamad Samuri Suzani , Md Yassin Sopia 
Published: October 2021

AbstractEarly childhood care and education (ECCE) is commonly understood in Malaysia as providing care and education for young children from the age of newborn until about six years old, before they enter formal elementary education. Various curriculum and teaching approaches were developed to enhance children's learning experiences based on their needs, age, and ability to support all three main developmental aspects: cognitive (language development and problem-solving skills), physical (development of gross and fine motor skills), and social-emotional (interaction with others). This paper will provide an overview of Malaysia's ECCE from its early implementation until today based on literature review of related research conducted in Malaysia. The definition of ECCE in Malaysia, its history and development, ECCE providers and type of institutions, current ECCE curriculum, and ECCE related acts in Malaysia are presented. In addition, the challenges faced, its consequences, and future course of ECCE in Malaysia are also discussed. It is envisaged that this article would be a platform for the relevant stakeholders worldwide to gain an insight on the Malaysian ECCE, serve as a benchmark and act as a reference for their respective ECCE settings.
Developing new antiferroelectric and ferroelectric oxides and chalcogenides within the A2BX3 family
Authors: Khan Aaliyah C. , Cook Autumn S. , Leginze Joshua A. , Bennett Joseph W. 
Published: October 2021

Abstract
Here, we employ first-principles methods to expand the set of functional materials known as ferroelectrics and antiferroelectrics. We use known compounds, whose properties have previously been overlooked, as the springboard for new materials. We first develop methodology to search for polar instabilities in known nonpolar and antipolar compounds and then use this technique to identify new members of the A2BX3 family. This methodology identities new Pb-free oxides and chalcogenides, with a wide range of band gaps, to be used as solid-state photovoltaics. Finally, we perform a cursory evaluation of how compositional tuning of oxide materials can adjust the difference in energy between ground and metastable states, to assess the likelihood of polarization switching. In total, we report on a targeted sets of new materials to synthesize and design routes to obtain ferroelectrics and antiferroelectrics with energetic barriers amenable to switching with an electric field.

Graphic abstract
3D printing nanocomposite hydrogels with lattice vascular networks using stereolithography
Authors: Kalossaka Livia M. , Mohammed Ali A. , Sena Giovanni , Barter Laura , Myant Connor 
Published: October 2021

AbstractHydrogels have emerged as leading candidates to reproduce native extracellular matrix. To provide structures and functions similar to tissues in vivo, controlled porosity and vascular networks are required. However, fabrication techniques to introduce these are still limited. In this study we propose stereolithography as a fabrication technique to achieve 3D vascular networks using water-based solvents only. A 3D printable hydrogel is formulated based on available commercial chemicals such as acrylamide (AAm) and polyethylene glycol diacrylate 700 (PEGDA700), with nanocellulose crystals (CNC) as a nanofiller. An optimisation procedure to increase resolution, tune porosity as well as mechanical properties is developed. The results highlight the importance of photoabsorber addition to improve channel resolution. We demonstrate that with the adequate choice of chemicals and fillers for photocurable formulations, structural and functional properties of the fabricated scaffold can be tailored, opening the path for advanced applications.
Graphic abstract
Economía social, crisis económicas y reestructuración del estado de bienestar
Authors: Inglada Galiana Elena , Pérez Chinarro Emilio , Manuel Sastre Jose 
Published: October 2021

Objetivo: el presente artículo pretende establecer una vinculación histórica y actual entre la evolución del Estado de bienestar, la economía social y las crisis económicas. De este objetivo general se deduce otro objetivo más concreto: trazar los vínculos entre el estadillo de la recesión económica iniciada en 2008 y las consecuencias en el Estado de bienestar en España.
Metodología: esta investigación se realiza con fuentes secundarias, mediante la revisión bibliográfica de aspectos teóricos del Estado del bienestar y la Economía Social. Se han analizado las consecuencias derivadas de la recesión, examinándose diferentes ámbitos de actuación correspondientes a las principales áreas que conforman la política social, fundamentalmente la vivienda, incluyéndose diversos indicadores —ejecuciones hipotecarias, desahucios o el PIB de las Comunidades Autónomas—. Para ello se ha trabajado a partir de una revisión bibliográfica de autores de referencia, revistas especializadas, sitios web y datos procedentes de fuentes gubernamentales (INE, Banco de España, entre otras).
Resultados: el resultado advertido es que el Estado del bienestar ha experimentado transformaciones en sus interpretaciones y puntos de vista marcados por los heterogéneos contextos políticos económicos y sociales que ha vivido en los últimos años. En el presente, no es resultado de un único factor sino de un compendio de escenarios políticos, sociales y laborales que traspasan nuestras fronteras debido a la globalización.
Conclusiones: se puede determinar que el futuro implica, necesariamente, una reestructuración del Estado del Bienestar dentro de las líneas generales de actuación que defiende la economía social.
Arborização Urbana na bacia do Rio Roncador em Duque de Caxias
Authors: Costa Thaís dos Santos , Silva Samantha Monteiro , Fonseca Jorge Nassar Fleury da 
Published: October 2021

O inchaço populacional das regiões centrais das grandes cidades e a expansão para as áreas periféricas adjacentes, configurando aquilo que se entende por expansão urbana, apontam para a necessidade de um planejamento que equacione o aumento dos serviços e das infraestruturas urbanas e garantia de um ambiente urbano de qualidade para a população. Tornar as cidades e os assentamentos humanos inclusivos, seguros, resilientes e sustentáveis é um desafio para os gestores públicos e planejadores urbanos. Entendendo a importância da arborização urbana para a melhoria da qualidade de vida dos habitantes das cidades, e para a construção de cidades habitáveis e resilientes, o presente trabalho aborda a arborização em uma área de expansão na Bacia do Rio Roncador, no município de Duque de Caxias, na Região Metropolitana do Rio de Janeiro. A partir de dados climáticos e de estudos de tendências de expansão urbana sobre as áreas de cobertura vegetal existentes no município, foi desenvolvido um diagnóstico quantitativo de arborização (levantamento in loco e imagens do satélite Landsat 8). O mapeamento da arborização foi associado aos dados de climatologia desenvolvidos pelos laboratórios DCLURME (UFRRJ) e LASA (UFRJ) e analisados segundo o índice ideal de arborização. Os mapas foram elaborados com o software QGIS. Os resultados apontam para condições de arborização muito aquém
Perceived barriers for performing regular physical exercises in non-exercising individuals of the age group 18 to 25 years
Authors: Godbole Sanika , Revadkar Mayur 
Published: October 2021

Background: This study was aimed to find out barriers for performing regular physical exercises among non- exercising individuals of the age group 18 to 25 years under the category of physical, mental, college/ work related, environmental, social and others and to explore differences in perception of barriers with regards to gender and profession.Methods: A questionnaire consisting of 36 items was prepared based on review of literature to assess the barriers for physical exercises. A google form link was sent across through social media platforms like WhatsApp, Instagram along with a video prepared by the researcher. Demographic details were filled and online consent was taken from 427 respondents. The 201 respondents fitting to the inclusion criteria were recruited. (Mean age 21.6±0.13 years).Results: The 47.1% respondents were found to be “non-exercising”. College/ work related barrier was reported to be a leading barrier followed by mental barrier. The least common barrier reported was social barrier. Conclusions: The detailed analysis of barriers across genders and professions provides insight to health professionals-physical therapists, general physicians, psychologists about impact of barriers in this age group. Combined efforts of all health professionals, college/ work institution authorities shall play a major part in policy formulation at college/ work institutions to promote physical exercise participation as college/ work related barrier was the leading barrier.
Assessment of the knowledge, attitude and practice of oral hygiene among primary school teachers in Navi Mumbai
Authors: Nakhawa Ojaswee D. , Hindalekar Manjusha S. , Deshmukh Ankita V. , Thakkar Vaibhav P. , Kulkarni Chinmayee V. 
Published: October 2021

Background: School age is an important stage in an individual’s development. Early education of oral hygiene by teachers can cause lifelong benefits to students since teachers are closely involved in children during their developmental stages. Oral diseases are becoming global issues and should be considered of public health importance. Yet, oral diseases are a neglected issue, rarely seen as a priority in health policy.Methods: This study is a descriptive cross-sectional study conducted in primary school teachers from Navi Mumbai, Maharashtra. Total 400 school teachers, selected by stratified sampling technique, had participated in this study. Participants were given self-structured questionnaires with 16 dichotomous questions.Results: 67.5% of teachers expressed that they have never received any demonstrations/lectures in maintaining oral hygiene while 82.8% never had any professional training regarding oral hygiene. For the question, Have you received training by a professional on oral health care and hygiene? teachers with less than 1 year of teaching experience 68.8% responded negatively, 78.8% with 1-5 years of experience reported with ‘no’ and 85.4% and 89.4% were negative responses from teachers with 6-10 years of teaching experience and 11-35 years of teaching experience respectively, showing significant value of p=0.026.Conclusions: From this study we understood that, some degree of awareness is seen in younger aged primary school teachers, but it is not satisfactory, suggesting that teachers still have to undergo training for the same. It is hoped that this survey will help in implementation of training programs.
Homecare: a strategy to ease the burden of Family Care Givers of clients with mental disorders: an overview
Authors: Mathew Suja Chungathil , Mathias Thereza 
Published: October 2021

Mental disorders are the second leading cause of disease burden in terms of Years Lived with Disability (YLDs) and the sixth leading cause of Disability-Adjusted Life-Years (DALYs) in the world in 2017. Mental disorders can lead to extreme physical, psychological, social and financial burden among the caregivers. Family is a basic unit of caring for the mentally ill. Empowering the family caregivers on caring their mentally ill client at home is an effective strategy in rehabilitation as the mental health facilities are limited in India. Home based care is known to reduce burden among the caregivers. Homecare includes various components that help in caring and managing clients with Activities of Daily Living (ADL), supervision and administration of medication, recreation and leisure activity, stress management, regular follow up with mental health professional, social skill training, management of psychiatric emergencies, management of potentially harmful behaviours such as suicide and anger management. The outcome of the home care of mentally ill depends on the willingness and cooperation of the family and continuous support and monitoring by the mental health team. It is cost-effective and implies the shift of responsibility not only on the hospital but on the family caregivers and the health professionals in the community.
A clinical study to assess disability and stigma associated with psoriasis
Authors: Khalid Ayesha , Chaudhary Savita , Saxena Kshitij , Paliwal Gaurav , Jain Chandni , Zaidi Aliza 
Published: October 2021

<p class="abstract"><strong>Background: </strong>Psoriasis relatively common, chronic, inflammatory and hyper-proliferative skin disease that affects 1.4% to 2.0 % of the population. Pateints with psoriasis have to face severe problems with stigmatization, discrimination and negative attitudes in general among the public, and often bear the brunt of public rejection.</p><p class="abstract"><strong>Methods: </strong>A cross-sectional observational study was carried out on psoriasis patients attending dermatology outpatient department of Era’s Lucknow medical college and hospital between November 2018 and November 2020. Patients with pustular psoriasis, mycosis fungoides, pityriasis rubra pilaris, and other severe medical conditions like heart failure, liver cirrhosis were excluded from the study.</p><p class="abstract"><strong>Results: </strong>Present study included 170 (aged 16 to 76 years; mean age 37.74±13.70 years; 62.4% males) clinically diagnosed patients of Psoriasis. P-score was observed with increase in Body Surface area, maximum for cases with BSA ≥25%. There was a strong positive significant linear correlation between stigmatization scores and disability scores (r=0.746; p&lt;0.001), thus indicating that with increase in p scores there was a significant increase in PDI scores and vice versa.</p><p class="abstract"><strong>Conclusions:</strong> Present study showed that feeling of stigmatization and disability was highly prevalent in psoriasis patients. It was seen that stigmatization and disability showed a strong correlation. The findings of study showed that there is need to create awareness regarding psoriasis as a non-communicable disease in order to increase the acceptance of psoriasis patients in society and to reduce their stigmatization.</p><p class="abstract"> </p>
La Posibilidad de renunciar a la acción de nulidad del laudo arbitral en el ordenamiento jurídico ecuatoriano
Authors: Guerra Romero Diego Mateo 
Published: October 2021

La acción de nulidad del laudo arbitral ha sido reconocida como el remedio procesal para la revisión de la validez del laudo bajo causales específicas determinadas en la ley. Sin embargo, esta revisión está prevista para ser ejecutada por órganos judiciales, lo que deviene en una inevitable interacción de la justicia ordinaria con el arbitraje. Esta inevitabilidad presenta una distinción, pues varias legislaciones extranjeras han previsto la posibilidad de excluir este control en la sede del arbitraje para extenderlo hacia la sede de ejecución.
Esto deviene en una discusión incierta sobre aquellos países que nada han establecido al respecto, como Ecuador, ya que la renuncia a esta acción podría estar prohibida por el ordenamiento en la medida en que trastoque limitantes de orden público. El análisis ecuatoriano indica que la renuncia, dentro de este ordenamiento, es factible siempre y cuando se acoja a un estándar que, precisamente, garantice este control.
Keanekaragaman Serangga Fitofag pada Sengon Falcataria moluccana (Miq.) Barneby & J.W. Grimes dari Jawa dan Hawaii di Persemaian di Bogor
Authors: Setyawan Yendra Pratama , Hidayat Purnama , Triwidodo Hermanu , Puliafico Kenneth 
Published: October 2021

Albizia (Falcataria moluccana) cultivated in Indonesia for timber plantations can increase the farmer’s income, even though albizia became an invasive alien species that can cause the economic and ecological losses. The controlling of invasive species using biological control is an effective method. The purpose of this study was to determine the phytophagous insects on albizia from Java and Hawaii in seedling in Bogor. The experiment was conducted in Carangpulang, Dramaga, Bogor. The experiment was arranged in a completely randomized block design using seed origin as a treatment (albizia Java and Hawaii) with 4 replicates. Total number of tree sample was 160 trees. Observations were conducted every 2 weeks until 32 weeks after planting. Identification of insects was conducted in the Laboratory of Insect Biosystematics, IPB. A total of 67 phytophagous insects were collected, 57 species in albizia from Java and 54 species in albizia from Hawaii. There was no difference in abundance and diversity of phytophagous insects on albizia from Java and Hawaii. Larvae of Eurema blanda (Lepidoptera: Pieridae) became an important pest causes leaf defoliation. Furthermore, Hulodes caranea (Lepidoptera: Noctuidae), Margarodes sp. (Hemiptera: Margarodidae), Choristoneura sp. (Lepidoptera: Tortricidae), and Adoxophyes sp. (Lepidoptera: Tortricidae) identified as important pests that have not been reported in the other research.

Keywords: albizia, defoliator insect, Fabaceae, important pests, invasive alien species
Aplikasi Analytical Hierarchy Process: Sistem Pendukung Keputusan untuk Seleksi Desa Inovasi di Wilayah Sorong
Authors: Ismail Ismail , Ulat Muhamad Ali , Muhfizar Muhfizar , Mustasim Mustasim , Poltak Hendra 
Published: October 2021

Rural-urban social inequality is a problem that must be solved to achieve prosperity and economic justice that is desired by all human beings. Efforts to overcome the problem are to create and carry out the Program of Marine and Fisheries Innovation Village which is a program of marine and fisheries community empowerment to be able to take advantage of technology and innovation as an effort to improve their lives. Limited budget and resources cause not all villages that are partners in community service at the Sorong Marine and Fisheries Polytechnic can be turned into Marine and Fisheries Innovation Villages. This research was conducted to determine the priority ranking of villages to be selected and to carry out innovation and technology interventions according to the predetermined criteria. Decision making in this marine and fisheries innovation village requires a systematic and accurate method using the Analytical Hierarchy Process (AHP). In the case study, the selection of the innovation village program was carried out at three locations in the Sorong area (Walal Village, Rimbapala Village, and Pulau Raam Village). The criteria used in the selection of alternative innovation villages were: 1) having local government support, 2) community response, 3) having superior fishery commodities, 4) accessibility, and 5) in accordance with the resources owned by the KP Sorong Polytechnic. The results obtained based on the AHP method were Raam Island 58,7%, Walal 21,9%, and Rimbapala 19,4%. The conclusion is that the village selected as the innovation village is Raam Island with the highest score of 58,7%.

Keywords: alternatives, analytical hierarchy process, criteria, innovation village, options
Status Daya Dukung Lahan untuk Keberlanjutan Pangan di Kabupaten Klungkung
Authors: Sudipa Nyoman 
Published: October 2021

Land is an essential component for the sustainability of human life. Population growth and urbanization affect the availability of land in an area. Therefore, the land never increases, but the need for land continues to grow every year, converted to housing and other facilities. As an area that continues to develop, Klungkung Regency has decreased the availability of land due to development and investment activities, especially tourism investment and the construction of other supporting facilities for tourism and regional development. Therefore, the availability of land in Klungkung Regency continues to experience pressure, which impacts the ability to provide food. This study aims to determine land requirements, land availability, and land carrying capacity status in Klungkung Regency, which the policy-makers can consider to support food sustainability in Klungkung Regency. This study uses a quantitative approach using primary data from direct observations in the field and secondary data from government and previous research. The results show that the carrying capacity of land in the Klungkung Regency is in deficit based on the projections for 2021 to 2030. In overcoming the land deficit, it is necessary to increase land productivity by using land effectively and technology transfer to increase food productivity.

Keywords: carrying capacity, food sustainability, Klungkung Regency land conversion