bluuebunny/crossref_metadata_2025_split huggingface dataset:
A control architecture for continuous production processes based on industry 4.0: water supply systems application
Authors: Chacón Edgar , Cruz Salazar Luis Alberto , Cardillo Juan , Paredes Astudillo Yenny Alexandra 
Published: June 2021

AbstractIndustry 4.0 (I4.0) brings together new disruptive technologies, increasing future factories’ productivity. Indeed, the control of production processes is fast becoming a key driver for manufacturing operations. Manufacturing control systems have recently been developed for distributed or semi-heterarchical architectures, e.g., holonic systems improving global efficiency and manufacturing operations’ reactiveness. So far, previous studies and applications have not dealt with continuous production processes, such as applications for Water Supply System (WSS), oil refining, or electric power plants. The complexity of continuous production is that a single fault can degrade extensively and even cause service disruption. Therefore, this paper proposes the Holonic Production Unit (HPU) architecture as a solution to control continuous production processes. An HPU is created as a holon unit depicting resources in a continuous process. This unit can detect events within the environment, evaluate several courses of action, and change the parameters aligned to a mission. The proposed approach was tested using a simulated model of WSS. The experiments described in this paper were conducted using a traditional WSS, where the communication and decision-making features allow the application of HPU. The results suggest that constructing a holarchy with different holons can fulfill I4.0 requirements for continuous production processes.
Viscoplastic flow of functional cellular materials with use of peridynamics
Authors: Postek Eligiusz , Nowak Zdzisław , Pęcherski Ryszard B. 
Published: June 2021

AbstractThe subject of the study is the deformation of the oxygen-free high conductivity copper. The copper sample is given in the form of a foam. The sample undergoes an impact into an elastic wall. The strain rate hardening effect is investigated. The numerical model of the open-cell foam skeleton is prepared in the framework of the peridynamics method. The dynamic process of compression with different impact velocities is simulated. It has been found that the strain rate hardening effect is essential for the load-carrying capacity of the material under study. Taylor impact test of solid cylinder analysis precedes the analysis of the metallic foam.
Recent advances in the structural diversity of reaction centers
Authors: Gisriel Christopher J. , Azai Chihiro , Cardona Tanai 
Published: June 2021

AbstractPhotosynthetic reaction centers (RC) catalyze the conversion of light to chemical energy that supports life on Earth, but they exhibit substantial diversity among different phyla. This is exemplified in a recent structure of the RC from an anoxygenic green sulfur bacterium (GsbRC) which has characteristics that may challenge the canonical view of RC classification. The GsbRC structure is analyzed and compared with other RCs, and the observations reveal important but unstudied research directions that are vital for disentangling RC evolution and diversity. Namely, (1) common themes of electron donation implicate a Ca2+ site whose role is unknown; (2) a previously unidentified lipid molecule with unclear functional significance is involved in the axial ligation of a cofactor in the electron transfer chain; (3) the GsbRC features surprising structural similarities with the distantly-related photosystem II; and (4) a structural basis for energy quenching in the GsbRC can be gleaned that exemplifies the importance of how exposure to oxygen has shaped the evolution of RCs. The analysis highlights these novel avenues of research that are critical for revealing evolutionary relationships that underpin the great diversity observed in extant RCs.
A worked example of Braun and Clarke’s approach to reflexive thematic analysis
Authors: Byrne David 
Published: June 2021

AbstractSince the publication of their inaugural paper on the topic in 2006, Braun and Clarke’s approach has arguably become one of the most thoroughly delineated methods of conducting thematic analysis (TA). However, confusion persists as to how to implement this specific approach to TA appropriately. The authors themselves have identified that many researchers who purport to adhere to this approach—and who reference their work as such—fail to adhere fully to the principles of ‘reflexive thematic analysis’ (RTA). Over the course of numerous publications, Braun and Clarke have elaborated significantly upon the constitution of RTA and attempted to clarify numerous misconceptions that they have found in the literature. This paper will offer a worked example of Braun and Clarke’s contemporary approach to reflexive thematic analysis with the aim of helping to dispel some of the confusion regarding the position of RTA among the numerous existing typologies of TA. While the data used in the worked example has been garnered from health and wellbeing education research and was examined to ascertain educators’ attitudes regarding such, the example offered of how to implement the RTA would be easily transferable to many other contexts and research topics.
Understanding potential implications for non-trophic parasite transmission based on vertebrate behavior at mesocarnivore carcass sites
Authors: Gonzálvez Moisés , Martínez-Carrasco Carlos , Moleón Marcos 
Published: June 2021

AbstractHigh infection risk is often associated with aggregations of animals around attractive resources. Here, we explore the behavior of potential hosts of non-trophically transmitted parasites at mesocarnivore carcass sites. We used videos recorded by camera traps at 56 red fox (Vulpes vulpes) carcasses and 10 carcasses of other wild carnivore species in three areas of southeastern Spain. Scavenging species, especially wild canids, mustelids and viverrids, showed more frequent rubbing behavior at carcass sites than non-scavenging and domestic species, suggesting that they could be exposed to a higher potential infection risk. The red fox was the species that most frequently contacted carcasses and marked and rubbed carcass sites. Foxes contacted heterospecific carcasses more frequently and earlier than conspecific ones and, when close contact occurred, it was more likely to be observed at heterospecific carcasses. This suggests that foxes avoid contact with the type of carcass and time period that have the greatest risk as a source of parasites. Overall, non-trophic behaviors of higher infection risk were mainly associated with visitor-carcass contact and visitor contact with feces and urine, rather than direct contact between visitors. Moreover, contact events between scavengers and carnivore carcasses were far more frequent than consumption events, which suggests that scavenger behavior is more constrained by the risk of acquiring meat-borne parasites than non-trophically transmitted parasites. This study contributes to filling key gaps in understanding the role of carrion in the landscape of disgust, which may be especially relevant in the current global context of emerging and re-emerging pathogens.
Graphical abstract
Leaf recognition using BP-RBF hybrid neural network
Authors: Yang Xin , Ni Haiming , Li Jingkui , Lv Jialuo , Mu Hongbo , Qi Dawei 
Published: June 2021

AbstractPlant recognition has great potential in forestry research and management. A new method combined back propagation neural network and radial basis function neural network to identify tree species using a few features and samples. The process was carried out in three steps: image pretreatment, feature extraction, and leaf recognition. In the image pretreatment processing, an image segmentation method based on hue, saturation and value color space and connected component labeling was presented, which can obtain the complete leaf image without veins and background. The BP-RBF hybrid neural network was used to test the influence of shape and texture on species recognition. The recognition accuracy of different classifiers was used to compare classification performance. The accuracy of the BP-RBF hybrid neural network using nine dimensional features was 96.2%, highest among all the classifiers.
Comprehensive study on the antioxidant capacity and phenolic profiles of black seed and other spices and herbs: effect of solvent and time of extraction
Authors: Muzolf-Panek Małgorzata , Stuper-Szablewska Kinga 
Published: June 2021

AbstractThe effects of solvent and time of extraction on the antioxidant properties and phenolic profiles of 13 herbs and spices used for food seasoning and preservation were investigated. The profiles of phenolics in plant material were analysed by UPLC, and the chemometric approach was used for the deeper evaluation of relationships between phenolic compounds and the antioxidant properties of the samples. The best extraction conditions enabling to obtain the highest total phenolics and the antioxidant activity were: long time extraction (24 h) with 50% aqueous ethanol. The most potent antioxidant was clove with the ABTS—2495.85 µmol/g, DPPH—1443.35 µmol/g and FRAP—1310.91 µmol/g, which resulted from the high total phenolic content (TPC—167.22 mg GAE/g) and total flavonoid content (TFC—26.22 mg QE/g). Wide variations in the antioxidant activity (ABTS: 7.31—2495.85 µmol/g) and TPC (0.87–167.22 mg GAE/g) were observed with black seed extract showing one of the lowest values of the parameters studied. High linear correlation (above 0.95) calculated for the parameters showed significant contribution of phenolics to the antioxidant activity of spices. UPLC analysis together with PCA (principal component analysis) confirmed this relation and ABTS, FRAP, DPPH, TFC, TPC, total phenolic acids, protocatechuic acid,t-cinnamic acid,p-hydroxybenzoic acid determined sample distribution along PC1 (principal component 1), whereas total flavonoids determined by UPLC, kaempferol, catechin and luteolin along PC2. All samples were discriminated with 100% classification’s propriety according to GDA (general discrimination analysis) which proved huge diversity among phenolic profiles and the antioxidant properties of tested samples.
Is One Anastomosis Gastric Bypass with a Biliopancreatic Limb of 150 cm Effective in the Treatment of People with Severe Obesity with BMI > 50?
Authors: Liagre Arnaud , Martini Francesco , Kassir Radwan , Juglard Gildas , Hamid Celine , Boudrie Hubert , Van Haverbeke Olivier , Antolino Laura , Debs Tarek , Petrucciani Niccolo 
Published: June 2021

Abstract
Purpose
The treatment of people with severe obesity and BMI > 50 kg/m2 is challenging. The present study aims to evaluate the short and mid-term outcomes of one anastomosis gastric bypass (OAGB) with a biliopancreatic limb of 150 cm as a primary bariatric procedure to treat those people in a referral center for bariatric surgery.

Material and Methods
Data of patients who underwent OAGB for severe obesity with BMI > 50 kg/m2 between 2010 and 2017 were collected prospectively and analyzed retrospectively. Follow-up comprised clinical and biochemical assessment at 1, 3, 6, 12, 18, and 24 months postoperatively, and once a year thereafter.

Results
Overall, 245 patients underwent OAGB. Postoperative mortality was null, and early morbidity was observed in 14 (5.7%) patients. At 24 months, the percentage total weight loss (%TWL) was 43.2 ± 9, and percentage excess weight loss (%EWL) was 80 ± 15.7 (184 patients). At 60 months, %TWL was 41.9 ± 10.2, and %EWL was 78.1 ± 18.3 (79 patients). Conversion to Roux-en-Y gastric bypass was needed in three (1.2%) patients for reflux resistant to medical treatment. Six patients (2.4%) had reoperation for an internal hernia during follow-up. Anastomotic ulcers occurred in three (1.2%) patients. Only two patients (0.8%) underwent a second bariatric surgery for insufficient weight loss.

Conclusion
OAGB with a biliopancreatic limb of 150 cm is feasible and associated with sustained weight loss in the treatment of severe obesity with BMI > 50 kg/m2. Further randomized studies are needed to compare OAGB with other bariatric procedures in this setting.

Graphical abstract
Association of cognitive impairment and breast cancer survivorship on quality of life in younger breast cancer survivors
Authors: Von Ah Diane , Crouch Adele D. , Monahan Patrick O. , Stump Timothy E. , Unverzagt Frederick W. , Storey Susan , Cohee Andrea A. , Cella David , Champion Victoria L. 
Published: June 2021

Abstract
Purpose
Younger breast cancer survivors (BCS) often report cognitive impairment and poor quality of life (QoL), which could be interrelated. The purpose of this study was to examine the association of cognitive impairment and breast cancer status (BCS versus healthy control (HC)), with QoL, which included psychological (depressive symptoms, well-being, perceived stress, and personal growth) and physical well-being (physical functioning and fatigue).

Methods
Four hundred ninety-eight BCS (≤45 years at diagnosis) who were 3 to 8 years post-chemotherapy treatment and 394 HC completed subjective questionnaires and a one-time neuropsychological assessment, including tests of attention, memory, processing speed, and verbal fluency. For each test, cognitive impairment was defined as scoring 1.5 and 2.0 standard deviations below the mean of the HC group. Separate linear regression models for each outcome were ran controlling for known covariates.

Results
BCS reported significantly more memory problems than HC (p < 0.0001), with up to 23% having significant impairment. Cognitive performance did not differ significantly between BCS and HCs. BCS vs. HCs had greater depression and fatigue, yet more personal growth. Objective and subjective cognitive impairment were significantly related to greater depressive symptoms and perceived stress and lower well-being and physical functioning; whereas, objective impairment was related to less personal growth and subjective impairment was related to greater fatigue.

Conclusions
Younger BCS report significant cognitive impairment years after treatment which may relate to greater decrements in QoL.

Implications to Cancer Survivors
Assessment and interventions to address cognitive concerns may also influence QoL outcomes in younger BCS.
Ossifying Fibroma of Non-odontogenic Origin: A Fibro-osseous Lesion in the Craniofacial Skeleton to be (Re-)considered
Authors: Baumhoer Daniel , Haefliger Simon , Ameline Baptiste , Hartmann Wolfgang , Amary Fernanda , Cleven Arjen , Klein Michael J. , Thompson Lester D. R. , Harder Dorothee , O’Donnell Paul 
Published: June 2021

AbstractIn the cranio-facial skeleton, a heterogeneous group of well characterized fibro-osseous lesions can be distinguished. Whereas fibrous dysplasia can affect any skeletal bone, ossifying fibroma and cemento-osseous dysplasia exclusively develop in the cranio-facial region, with most subtypes restricted to the tooth bearing areas of the jaws. Herein we present a series of 20 fibro-osseous lesions that developed mostly in the frontal bone and in the mandible, presenting as expansile intramedullary tumors with a unique histologic appearance and an indolent clinical course. We provide evidence that these tumors are distinct from the categories included in the WHO classification and are therefore currently unclassifiable. The definition of cemento-ossifying fibroma as an odontogenic neoplasm developing only in close proximity to teeth should be re-considered and incorporate also extragnathic lesions as shown here.
Atlas der SARS-CoV-2-RNA-Protein-Interaktionen in infizierten Zellen
Authors: Schmidt Nora , Munschauer Mathias 
Published: June 2021

AbstractUsing RNA antisense purification and mass spectrometry, we identified more than 100 human proteins that directly and specifically bind SARS-CoV-2 RNA in infected cells. To gain insights into the functions of selected RNA interactors, we applied genetic perturbation and pharmacological inhibition experiments, and mapped the contact sites on the viral RNA. This led to the identification of host dependency factors and defense strategies, which can guide the design of novel therapeutics against SARS-CoV-2.
Superaufgelöste Mikroskopie: Pilze unter Beobachtung
Authors: Sputh Sebastian , Panzer Sabine , Stigloher Christian , Terpitz Ulrich 
Published: June 2021

AbstractThe diffraction limit of light confines fluorescence imaging of subcellular structures in fungi. Different super-resolution methods are available for the analysis of fungi that we briefly discuss. We exploit the filamentous fungus Fusarium fujikuroi expressing a YFP-labeled membrane protein showing the benefit of correlative light- and electron microscopy (CLEM), that combines structured illumination microscopy (SIM) and scanning election microscopy (SEM).
Safety first: das Ubiquitin-Proteasom-System (UPS) und die Photosynthese
Authors: Grimmer Julia , Baginsky Sacha 
Published: June 2021

AbstractThe proteasome is essential for the control of protein turnover in the nucleus and the cytosol of eukaryotic cells. Chloroplasts and mitochondria import thousands of nuclear-encoded proteins as precursor proteins from the cytosol. We show that mild genetic proteasome impairment interferes with a cytosolic equilibrium between precursor protein import and degradation resulting in elevated precursor protein abundance in the cytosol and improved photosynthetic performance.
Gestörter Kerntransport und Phasentrennung von RNA-Bindeproteinen
Authors: Hutten Saskia , Dormann Dorothee 
Published: June 2021

AbstractAmyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal neurodegenerative disordes, whose underlying molecular mechanisms are only beginning to emerge. A common molecular hallmark of both diseases is the relocalization of nuclear RNA-binding proteins (RBP) into cytoplasmic aggregates. Defects in nuclear import and aberrant phase separation appear to underlie RBP mislocalization and aggregation and could potentially be targeted in future therapies.
iPS-abgeleitete Kardiomyozyten als therapeutische Hoffnungsträger
Authors: Grill Nina , Fellner Lisa , Tisch Marcel , Edenhofer Frank 
Published: June 2021

AbstractAfter ischemic injury in adolescence, the human heart has only limited capacity to regenerate. The loss of cardiomyocytes is typically replaced by fibrotic scar tissue. The resulting scars reduce myocardial contractility and function. To date, the gold standard for end-stage heart disease remains a heart transplant, which is not a realistic option due to donor heart shortage. The regenerative potential of reprogrammed stem cells has the potential for a long-expected breakthrough in development of efficient therapeutic interventions.
Assessing hydrocarbon prospects in Abu Madi formation using well logging data in El-Qara field, Nile Delta Basin, Egypt
Authors: Sarhan Mohammad Abdelfattah 
Published: June 2021

AbstractIn this work, the petrophysical properties of Abu Madi reservoir in El-Qara Field at northern Nile Delta Basin (NDB) were evaluated depending on well logging data of two wells: El-Qara-2 and El-Qara-3. This evaluation revealed that in El-Qara-2 well, the promising gas zone is detected between depths of 3315 and 3358 m, while in El-Qara-3 well, the best gas interval is detected between depths of 3358 and 3371 m. In addition to the production test parameters (gas rate, condensate rate, gas gravity, condensate gravity, gas-to-oil ratio, flowing tubing head pressure, flowing bottom hole pressure, and static bottom hole pressure), the calculated petrophysical parameters (shale volume, total porosity, effective porosity, and water saturation) for both intervals were relatively similar. This confirms that the investigated wells were drilled at the same reservoir interval within Abu Madi Fm. The depth variation in the examined zones was attributed to the presence of buried normal faults between El-Qara-2 and El-Qara-3 wells. This observation may be supported from the tectonic influence during the deposition of Abu Madi Fm. as a portion of the Messinian syn-rift megasequence beneath the NDB.
Ultrasound Imaging of the Spine for Central Neuraxial Blockade: a Technical Description and Evidence Update
Authors: Kalagara Hari , Nair Harsha , Kolli Sree , Thota Gopal , Uppal Vishal 
Published: June 2021

AbstractPurpose of ReviewThis article describes the anatomy of the spine, relevant ultrasonographic views, and the techniques used to perform the neuraxial blocks using ultrasound imaging. Finally, we review the available evidence for the use of ultrasound imaging to perform neuraxial blocks.Recent FindingsCentral neuraxial blockade using traditional landmark palpation is a reliable technique to provide surgical anesthesia and postoperative analgesia. However, factors like obesity, spinal deformity, and previous spine surgery can make the procedure challenging. The use of ultrasound imaging has been shown to assist in these scenarios.SummaryPreprocedural imaging minimizes the technical difficulty of spinal and epidural placement with fewer needle passes and skin punctures. It helps to accurately identify the midline, vertebral level, interlaminar space, and can predict the depth to the epidural and intrathecal spaces. By providing information about the best angle and direction of approach, in addition to the depth, ultrasound imaging allows planning an ideal trajectory for a successful block. These benefits are most noticeable when expert operators carry out the ultrasound examination and for patients with predicted difficult spinal anatomy. Recent evidence suggests that pre-procedural neuraxial ultrasound imaging may reduce complications such as vascular puncture, headache, and backache. Neuraxial ultrasound imaging should be in the skill set of every anesthesiologist who routinely performs lumbar or thoracic neuraxial blockade. We recommend using preprocedural neuraxial imaging routinely to acquire and maintain the imaging skills to enable success for challenging neuraxial procedures.
Fishing against the odds: fishers’ motivations to carry on fishing in the wake of the hindering EU Common Fishery Policy—a case study in North Shields, UK
Authors: Christy Des , de Jong Edwin B. P. , Knippenberg Luuk 
Published: June 2021

AbstractThe UK’s fishing industry has contracted considerably since 1972 due to overfishing, increased fuel prices, and implementation of the European Union (EU) Common Fisheries Policy (CFP). Despite this decline affecting the industry at large and the incomes of fishers, some fishers have carried on, or even freshly started or returned to the business. Why have these fishers done so despite the challenges they encounter in the fishing industry? In this article, we investigate why some fishers still choose to fish in the wake of all the EU regulations designed to control overfishing by reducing the size of the industry and discouraging entry by taking measures that affect revenues. Our data are collected through ethnographic research involving participant observation and interviews with fishers in North Shields, England. Based on our findings, we argue that the decision to carry on fishing, or even to return, is predominantly based on so-called intrinsic motivations, rather than on cost-benefit calculations, and stems from three interlinked basic human emotional needs which fishing seems to fulfil: the need to connect (sometimes also defined as the need to relate or belong); the desire for autonomy; and the desire to show competence (and have that competence recognized by relevant others). As such, the findings offer a fresh way to explain fishers’ decisions, based on a deliberated choice, to remain or leave the sector, and to understand and interrogate the challenges confronting present-day fishing both on a local level in the UK and also for Europe at large.