bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is the increase of uric acid associated with the components of the metabolic syndrome?
Authors: Sudmantaitė Vaida , Mikolaitytė Jurgita , Badarienė Jolita , Čypienė Alma , Jucevičienė Agnė , Rutkauskienė Irma , Puronaitė Roma , Laucevičius Aleksandras 
Published: April 2021

Summary

Objectives: There is increasing evidence that metabolic syndrome (MetS) may be associated with increased uric acid levels. Previous studies indicate that hyperuricaemia is an independent risk factor for cardiovascular disorders. We sought to determine the association of serum uric acid (SUA) with MetS components and other cardiovascular risk factors among middle aged Lithuanians with MetS.

Design and methods: A cross-sectional study was conducted in 2018. A total of 705 subjects aged 40 to 65 years with MetS diagnosed using NCEP ATP III criteria were included. None of the participants had previously diagnosed cardiovascular, cerebrovascular, peripheral artery or end-stage oncological disease. Blood tests and all anthropometric measurements were obtained using standard methods. Subjects were divided into 2 groups: with hyperuricaemia and without hyperuricaemia.

Results: Hyperuricaemia was found in 33.3% of subjects. Mean serum uric acid level increased as the number of metabolic factors increased. Participants with hyperuricaemia had abnormal waist circumference (p < 0.001), higher systolic (p = 0.001) and diastolic blood pressure (p = 0.003), higher levels of triglycerides and, lower levels of high-density lipoprotein cholesterol (p < 0.001). Subjects in hyperuricaemia group were more likely to be alcohol users (p = 0.034), to have diabetes (p = 0.02) and higher body mass index (p < 0.001). Their creatinine levels were statistically significantly higher (p < 0.001).

Conclusions: Our analysis showed that serum uric acid is associated with MetS and other cardiovascular risk factors. The study found a statistically significant association with the four out of five components of the MetS (excluding plasma glucose) as well as with alcohol consumption, and renal function indicators (creatinine, eGFR).
Recurrent Pregnancy Induced Pemphigus Vulgaris: A Rare Case Report
Authors: Azwir Irsalina Husna , Djawad Khairuddin , Waspodo Nurelly N. , Madjid Asnawi 
Published: April 2021

Abstract
Pemphigus vulgaris is a potentially life-threatening bullous autoimmune disease that can be triggered by various factors, one of which is pregnancy. Cases of pregnancy induced pemphigus are rare, and can result in devastating outcomes, both from the maternal or fetal perspectives if not treated promptly and adequately. The use of systemic corticosteroids is paramount to improve the outcome of the patient and fetus and it is a first-line treatment for the disease. Patients with a history of pemphigus should plan their pregnancies carefully, taking into consideration a minimum of 6 months remission before conception. This case report is about a 28-year-old woman with a history of pemphigus vulgaris that did not seek medical treatment of her pemphigus, which resulted in the intrauterine fetal death. The patient was treated with systemic corticosteroids and achieved great resolution to her blisters and overall wellbeing.
Harlequin Ichthyosis (HI) Associated with Atrial Septal Defect (ASD) and Choanal Atresia
Authors: Deshmukh Nitika S. , Gosavi Anil , Chavan Ravindranath B. , Belgaumkar Vasudha A. 
Published: April 2021

Abstract
Harlequin ichthyosis (HI) is a severe form of congenital ichthyosis with autosomal recessive inheritance. Incidence of harlequin ichthyosis is 1 in 3,00,000 live births. We report a case of HI associated with bilateral choanal atresia and atrial septal defects, which is a rare association in this skin disorder. A-month-old preterm male baby born out of consanguineous marriage presented with features of armour-like scales and erythema all over body, ectropion, eclabium and fissures over flexures. The patient was born with a colloidion membrane at birth. The baby was operated for bilateral choanal atresia soon after birth because he developed cyanosis upon breast feeding which improved on crying. Upon flexible nasal endoscopy, diagnosis of membranous type of choanal atresia was confirmed by ENT (ear, nose, throat) surgeon. Heart auscultation revealed a murmur in our patient. Electrocardiogram and 2D Echocardiography was reported as atrial septal defect (4.5 mm OsASD). The patient was started on acitretin (1 mg/kg/day) and emollients after complete evaluation and is currently on regular follow up. Harlequin ichthyosis is linked to mutation of ABCA12 gene. It is often associated with eclabium, ectropion, hypoplastic nose, ears and fingers. Congenital heart diseases are rarely reported with HI in literature. This makes it mandatory to screen HI patients for internal defects.
Psychometric Properties of the Quality of Life Questionnaire - Cervical Cancer 24 (QLQ CX 24) Translation to Serbian
Authors: Zaric Radica Zivkovic , Radojevic Marija Zivkovic , Krasic Katarina , Milovanovic Jasmina , Jankovic Slobodan 
Published: April 2021

Abstract
Cancer of the cervix has a progressive character and is one of the most significant public health problems in many countries. Our research aimed to translate EORTC QLQ CX 24 (European Organization for Research and Treatment of Cancer; Quality of life questionnaire-cervical cancer 24) from English to Serbian, to create essential cultural adaptations and to analyze psychometric properties of the translation in a model of female inpatients with cancer of the cervix. The QLQ CX 24 was translated and adapted according to internationally established guidelines, and then tested on a sample of 100 Serbian females with cancer of the cervix. The testing was repeated three times on the same patients. We calculated the internal consistency (Cronbach’s alpha), criterion validity, convergent validity, and discriminative validity of the QLQ CX 24. We used factor analysis to discover the original construct. The Serbian translation of QLQ CX 24 showed good internal consistency, showed satisfactory reliability, and temporal stability. In the first, when was rated by the investigators Cronbach’s alpha was 0.607, and one month later when the questionnaire also was rated by investigators Cronbach’s alpha was 0.696. When the scale was rated by females themselves Cronbach’s alpha was 0.802. Divergent as well as convergent validity tests had good results. The factorial analysis exposed six domains. The Serbian translation of QLQ CX 24 is a trustworthy and appropriate specific instrument for measuring the quality of life in females with cervical cancer.
An examination of retailers’ compliance with the minimum legal drinking (purchasing) age law in Slovenia: A quasi-experimental intervention study
Authors: Kamin Tanja , Čož Sinja , Atanasova Sara 
Published: April 2021

Abstract

Introduction
Alcohol consumption among young people is strongly related to alcohol availability. The minimum legal drinking (purchasing) age (MLDA) is a legal measure that regulates alcohol availability to minors in Slovenia. This study examines (1) retailers’ compliance with the MLDA law in Slovenia and (2) the effectiveness of two interventions directed at cashiers in off-premise stores.

Methods
The study uses a non-randomized quasi-experimental design to evaluate the effectiveness of (1) a communication intervention directed at off-premise store managers, and (2) an intervention by the Slovene Market Inspectorate. The first intervention focused on informing cashiers about MLDA’s importance and their role as gatekeepers of young people’s health, while the second involved law enforcement. Using the mystery shopping protocol, we conducted two waves of purchase attempts with decoy underage shoppers pre- and post-intervention in 97 off-premise stores. We collected data on the shopping process at the point of sale and conducted 40 semistructured interviews with cashiers to evaluate the barriers and incentives regarding MLDA compliance.

Results
Retailers’ initial noncompliance rate with MLDA in off-premise stores was high, but improved significantly after the law enforcement intervention. We identified a significant correlation between the cashiers’ ID requests and the refusal of alcohol sales, but cashiers’ ID requests remained low. Qualitative findings reveal that cashiers experience several issues when handling MLDA in practice.

Conclusion
Noncompliance with MLDA persisted even after the law enforcement intervention, revealing the need for policy makers to introduce new strategies for MLDA enforcement, such as revocable alcohol licenses for off-premise stores.
Algorithmicity of Evolutionary Algorithms
Authors: Leciejewski Sławomir , Szynkiewicz Mariusz 
Published: April 2021

Abstract
In the first part of our article we will refer the penetration of scientific terms into colloquial language, focusing on the sense in which the concept of an algorithm currently functions outside its original scope. The given examples will refer mostly to disciplines not directly related to computer science and to the colloquial language. In the next part we will also discuss the modifications made to the meaning of the term algorithm and how this concept is now understood in computer science. Finally, we will discuss the problem of algorithmicity of evolutionary algorithms, i.e. we will try to answer the question whether – and to what extent – they are still algorithms in the classical sense.
Summary Strategies for Literary Texts in English
Authors: Malaj Lavdosh 
Published: April 2021

Abstract
One of the problems when students go to university is that they are faced with insufficient skills (reading, summarizing and writing). These skills are not just an option for students – they are a necessity. One of these skills is text summarizing. Summarizing strategies may be called the gist of the literary text. Different summarization strategies may be required for different text types and lengths. The ability to summarize well means your reading comprehension and writing skill should be excellent. Summarization is a high-level comprehension strategy which is effective in improving reading achievement and text summary quality.
Several approaches have been developed to analyse summarizing skills which are required to teach and learn English at all levels especially at university level. The research was conducted among students of the second year English department at University of Vlora. The summaries reflect the major differences among the strategies used by skilled and unskilled students. The skilled students produce coherent linguistic and syntactic structures. Skilled (high-proficiency) students use semantic and prepositional phrases more than unskilled students (low-proficiency). Thus, the skilled students do not distort ideas of the original text but distort subject-verb order. When they summarize, we can easily distinguish the way in which they combine idea units across two or more paragraphs. The summaries reflect that students write very long sentences. The margin of errors is considerable due to the mother tongue influence and their level of English.
The Roles of Women in the Lexicon of the Albanian “Code of Skanderbeg” (Kanuni I Skanderbegut)
Authors: Genesin Monica 
Published: April 2021

Abstract
A lexical analysis of the so-called Kanuni i Skanderbegut, an Albanian collection of customary laws, provides an insight to understand women’s social role in traditional communities living in the northern area of Albania. In the use of specific terminology one can notice a clear separation between the two sexes which is reflected in the distribution of roles and in using a structured terminology that designates not only roles and conditions, but also other aspects of social life.
Interreligious Dialogue in the Renaissance: Cusanus, De Pace Fidei
Authors: Rizzo Luana 
Published: April 2021

Abstract
The paper examines the Dialogue De pace fidei written by Nicolaus Cusanus in 1453 to settle disputes arising from events that triggered religious unrest, such as the fall of Constantinople in May 1453, the invasion and massacre of the Turks led by Sultan Mehmed II and the defeat of the Christians. Following the disintegration of medieval Christianity, Cusanus, instead of promoting a crusade, as Cardinal Bessarione did, proposed a more suitable way to make the major exponents of different religions interact in a fruitful dialogue, hoping for the peace of a single universal faith. The arguments through which Cusanus claimed the concept of a concordance and pacification of the faith reveal the originality and topicality of the message communicated by the humanist, founded on the doctrine of peace in the faith, overcoming inter-confessional barriers and religious divergences.
The author contrasts the divergences, massacres and wars with a doctrinal comparison among different religions through dialogue. The paper invites reflection upon the religious struggles that still spread discord in the world.
Features of Organic Agricultural Products Functioning in EU and Ukraine
Authors: Burliai Alina , Burliai Oleksandr , Nesterchuk Yulia , Revutska Alla 
Published: April 2021

Abstract
Organic agriculture ensures a balanced state of the ecosystem, which is the key to sustainable development of the economic and social spheres of society. European countries are in the process of historical development reached an understanding on the need for its further ecological progress. That is why the world market for organic products has formed. Studies show that the development of organic production began in the 20‘s of the twentieth century. Since then, markets for organic products began to grow rapidly in many countries. Among the world‘s regions, the largest areas of organic land are located in Oceania and Europe. The article is devoted to the study of foreign experience in the development of ecological agriculture. The variety of names of ecological systems of management in the countries of the world and the principles which are included in the concept “ecological agriculture“ are studied. The history of the emergence of organic agriculture has been explored. The analysis of the development of organic agricultural production at the world level, the countries of Europe and the European Union (EU) and individual countries has been analyzed. A grouping of organic farms in Europe has been organized in terms of size. Ukraine, with its significant natural and economic potential in the future may also be one of the important subjects that will form a proposal in this market. The environmental policy of the country has an important influence on the efficiency of organic farms.
Non-suicidal self-injury in patients with eating disorders: nuclear aspects
Authors: Rodríguez-López Alvaro , Rodríguez-Ortíz Erika , Romero-Gonzalez Borja 
Published: April 2021

Background: Through the culture of thinness, increasingly promoted in our society as a beauty canon, it is not surprising that the number of people affected by eating disorders is increasing.
Objective: This research aims to study the relationship between non-suicidal self-injuries and nuclear aspects of eating disorders specified along with this article.
Methods: The sample consisted of 60 women diagnosed with anorexia and bulimia. Questionnaires assessing impulsivity, body satisfaction, alexithymia, body attitude and self-esteem were administered. Participants with non-suicidal self-harm were compared with those without, and participants with anorexia with and without self-harm and participants with bulimia with and without self-harm were compared.
Results: Differences were found in body dissatisfaction = 5,71; p ≤ ,01), body attitudes = 4,80; p ≤ ,02), self-esteem = 14,09; p ≤ .00) and impulsivity (t = 3,39; p ≤ ,01) between participants with and without non-suicidal self-harm.
Conclusions: These are key factors for the clinic in the treatment of eating disorders to prevent the presence of self-harm, as it allows focusing the treatment target on those aspects such as dissatisfaction and impulsivity, which are key in the development of self-harm.
PENGARUH PAJAK, TUNNELING INCENTIVE, MEKANISME BONUS DAN PROFITABILITAS TERHADAP TRANSFER PRICING
Authors: Mineri Michelle Filantropy , Paramitha Melvie 
Published: April 2021

Pajak merupakan salah satu sumber penerimaan terbesar bagi negara. Membayar pajak adalah kewajiban yang harus dilakukan baik oleh orang pribadi maupun badan. Perencanaan pajak merupakan cara yang dapat dilakukan untuk dapat mengurangi beban pajak yang dibayarkan, salah satunya yaitu melalui transfer pricing. Akan tetapi, hal tersebut dapat mengurangi pendapatan negara. Penelitian ini bertujuan untuk mengetahui pengaruh Pajak, tunneling incentive, Mekanisme Bonus dan Profitabilitas Terhadap transfer pricing pada Perusahaan Manufaktur yang Terdaftar di Bursa Efek Indonesia Tahun 2016 – 2019. Penelitian ini menggunakan data sekunder sebanyak 174 perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia. Pemilihan sampel menggunakan metode purposive sampling, sehingga ditemukan sampel penelitian sebanyak 25 perusahaan. Periode tahun yang digunakan oleh peneliti adalah dari tahun 2016 – 2019. Hasil dari penelitian menggunakan SmartPLS menunjukkan bahwa variabel tunneling incentive berpengaruh positif dan signifikan terhadap transfer pricing dan variabel profitabilitas berpengaruh negatif dan signifikan terhadap transfer pricing . Sedangkan variabel pajak dan mekanisme bonus tidak berpengaruh signifikan terhadap transfer pricing .
GRAMMATICAL ERRORS IN LITERATURE AND PHILOSOPHY STUDENT ESSAYS AT PANCA MARGA UNIVERSITY, PROBOLINGGO
Authors: Masluha Siti 
Published: April 2021

Abstract: This study is to analyze the subsconcious communicative competence using argumentative reading for post-beginner student in reading class. The theory used in this study is the communicative competence theory developed by Savignon and linguistic competence developed by Canale and Swain. The method used is classroom action research. The finding of this study is improving the subsconcious communicative competence using argumentative reading. The finding of this study are expected to have not only practical significance, but to a certain degree also theoritical significance.
Keywords: subconscious, communicative, argumentative reading
ANALISIS PENGARUH PENERIMAAN PESERTA DIDIK BARU MELALUI SISTEM ZONASI TERHADAP PRESTASI BELAJAR
Authors: Sulaiman Sulaiman , Nurfitrah Lubis Laila , Aditya Rizky 
Published: April 2021

Penelitian ini bertujuan untuk melihat pengaruh sistem zonasi terhadap prestasi belajar siswa kelas XI SMA Negeri 6 Pontianak. Dalam penelitian ini diambil sampel sebanyak 88 orang dengan menggunakan analisis regresi. Sumber data yang diperoleh adalah data primer dan data sekunder. Dengan pendekatan kuantitatif. Teknik data melalui teknik wawancara, observasi dan dokumentasi. Teknik analisis data menggunakan uji asumsi, analisis deskriptif dan analisis statistik dengan regresi linier menggunakan SPSS (Social Sciences Program Statistics) versi 22.0Hasil penelitian menunjukkan bahwa zonasi terhadap prestasi belajar siswa kelas XI SMA Negeri 6 Pontianak berpengaruh positif. Berdasarkan hasil perhitungan diperoleh nilai thitung (6,863)> t tabel (0,270) dan nilai signifikan (0,000) <0,05, maka hipotesis (Ho) diterima, artinya terdapat pengaruh positif yang signifikan antara variabel sistem zonasi terhadap Prestasi Belajar Siswa Kelas XI SMA Negeri 6 Pontianak. Kata Kunci: Sistem Zonasi, Prestasi, Pembelajaran
Analytical Performance of a FRET-Based Point-of-Care Immunoassay for the Quantitation of C-Reactive Protein in Serum and Finger Prick Capillary Whole Blood
Authors: Reddy Rukmini , Srikrishnan Raj , Bahur Bayda , Chon Kevin , Westin Stefan , Wong Matthew , Sagoe Bright , Bray Kurt , Day Valerie , Mimms Larry , Hale Michael 
Published: April 2021

Time-resolved fluorescence resonance energy transfer (FRET) provides a useful technology for immunoassay measurement of proteins, This has been used to develop an immunoassay for C-reactive protein (Procise CRP™) that provides point-of-care measurement of CRP in less than 4 minutes using 20 µL of either whole blood or serum. Analytical studies of the assay on the ProciseDx™ analyzer were performed to characterize its measurement capabilities.Sensitivity, specificity, linearity, and precision - including reproducibility of finger prick blood collection and testing, suitable for routine clinical use in a point-of-care setting were demonstrated for the CRP assay. It also showed excellent analytical agreement with a current commercial CRP test. These results indicate the Procise CRP assay is useful for obtaining fast and accurate CRP quantitation in a point of care setting that can aid in the immediate assessment of patients’ inflammatory status.
PEMBERDAYAAN KELOMPOK NELAYAN MELALUI MEDIA KOMUNIKASI LUAR RUANGAN DI DESA GRUJUGAN KECAMATAN GAPURA
Authors: Yuliastina Roos , Inayati Hosnu 
Published: April 2021

Pemberdayaan Kelompok Nelayan Melalui Media Komunikasi di Desa Grujugan Kecamatan ini adalah tindak lanjut dari kegiatan penelitian yang dilakukan pada kelompok nelayan di lokasi yang sama dari persepektif komunikasi kesehatan. Kegiatan pengabdian ini lebih menekankan pada bentuk pendampingan melalui kegiatan sosialisasi penerapan perilaku hidup sehat dan bersih (PHBS) dalam kegiatan sehari-hari. Tujuan dari kegiatan pengabdian ini berupaya untuk mengedukasi dan memberdayakan masyarakat pesisir, khususnya kelompok nelayan di dusun Palegin dan dusun Karang Mimbah desa Grujugan Kecamatan Gapura dari aspek komunikasi kesehatan. Metode kegiatan yang dilakukan (1) kegiatan sosialisasi tentang manfaat dan dampak jika menerapkan berprilaku hidup sehat dan bersih (PHBS). Seperti membasuh tangan sebelum makan, tidak membuang sampah sembarangan, dan tidak buang air besar (BAB) sembarangan. (2) melakukan kampanye penerapan PHBS melalui media komunikasi luar ruangan, melalui pemasangan Banner dan poster. Media kampanye PHBS dipasang pada lokasi – lokasi strategis seperti di kantor balai desa dan rumah warga yang dan pertokoan di desa setempat. Adapun isi kampanye media luar ruangan tersebut, adalah tatacara perilaku hidup bersih dan sehat serta penerapan protokoler kesehatan sesuai standar covid - 19. Luaran kegiatan PkM ini diantaranya; 1) Publikasi pada jurnal pengabdian e-ISSN, 2) Publikasi melalui media online, 3) Hak Cipta – karya seni berupa poster kegiatan PkM.
On Fair Performance Comparison between Random Survival Forest and Cox Regression: An Example of Colorectal Cancer Study
Authors: Cetin Sirin , Ulgen Ayse , Dede Isa , Li Wentian 
Published: April 2021

Random Forest (RF), a mostly model-free and robust machine learning method, has been successfully applied to right-censored survival data, under the name of Random Survival Forest (RSF). However, RF/RSF has its distinct strategies in classification and prediction. First, it is an ensemble classifier and its performance is an average of multiple rounds of data fitting. Second, the training set is a bootstrap (sampling with replacement) generated set with repeated used of roughly 2/3 of all samples and testing set consists of those not used (out of bag samples). Both features are not intrinsic to Cox regression or other single classifiers. Not considering these two features could potentially lead to a partial comparison between the performance of the two methods. By using a colorectal survival dataset, we illustrate the problems of using k-fold cross-validation, using only one resampling without an ensemble average, and using the whole dataset for both fitting and testing, in Cox regression, when comparing with RSF. We provide a more accessible R code for simple calculation of discordance index (D-index) and unweighted integrated Brier score (IBS) for Cox regression, and unweighted IBS for RSF. Doi: 10.28991/SciMedJ-2021-0301-9 Full Text: PDF