bluuebunny/crossref_metadata_2025_split huggingface dataset:
Les savoirs infirmiers liés au care exprimés dans les gestes professionnels
Authors: Eyland Isabelle 
Published: May 2021

Introduction : historiquement, il est admis que les femmes soignantes ont toujours eu des fonctions liées au care . Il s’exprime selon des modalités différentes dans des gestes professionnels. Contexte : dans un contexte où l’activité des infirmières est davantage centrée sur les actes techniques et sur le cure , nous pouvons nous interroger sur la place des savoirs professionnels liés au care dans les soins. Objectif : cet article a pour objet de présenter des résultats d’une recherche qui s’intéresse à l’identification de gestes professionnels liés au care dans l’activité des infirmiers en situations de soins et de leurs liens avec les savoirs infirmiers. Méthode : la recherche a été menée dans le cadre de la clinique de l’activité, en utilisant l’autoconfrontation simple et l’instruction au sosie. Les données ont été recueillies auprès d’infirmiers libéraux par des enregistrements et des prises de notes, puis analysées dans le but de les catégoriser en utilisant les cadres de références de l’analyse lexicale, des topiques énonciatives et de la typologie des savoirs infirmiers. Résultats : quatre types de gestes professionnels liés au care ont été identifiés : des gestes d’ambiance, des gestes de sollicitude, des gestes d’évaluation et des gestes de régulation. Les résultats ont permis de schématiser un outil d’analyse de ces gestes professionnels liés au care . Discussion : les gestes professionnels liés au care existent et sont identifiables. L’analyse des résultats confirme que l’expérience transforme les savoirs de natures différentes en savoirs pratiques. Conclusion : la confrontation entre exercice professionnel et les différents types de savoirs acquis permet la construction des savoirs professionnels.
La guerre des langues : pourquoi l’hébreu a triomphé
Authors: Bendavid Ariane 
Published: May 2021

Dans les dernières décennies du xixe siècle et les premières du xxe, un choix décisif se présentait aux juifs d’Europe de l’Est soucieux d’une part de maintenir en vie leur patrimoine littéraire et d’autre part d’assurer au foyer juif en construction en Palestine une langue parlée commune. Cette période durant laquelle se sont affrontés hébraïsants et yiddishisants, a vu le triomphe de l’hébreu comme langue nationale parlée. C’est ce conflit, parfois virulent, que je vous propose d’aborder ici.
La littérature française vue par Rachel
Authors: Grasset Bernard 
Published: May 2021

Cet article propose la présentation et la traduction à partir de l’hébreu de trois articles de la poétesse Rachel consacrés à des écrivains français et qui se suivent dans l’édition de ses écrits : Anatole France en pantoufles, J. Jolinon et Clarté. Ils nous permettent de découvrir comment une poétesse juive, de langue hébraïque, comprenait la littérature française au début du xxe siècle, quels auteurs elle lisait et ce qu’elle en retenait. Par contrepoint, ils laissent transparaître ce que Rachel cherchait elle‑même en écrivant.
Integrating an Evidence-Based Medicine Curriculum into Physician Assistant Education
Authors: Reinhold Martina Ingeborg , Bacon-Baguley Theresa Ann 
Published: May 2021

Background:
Medical knowledge continuously evolves and to help health care providers to stay up to date, the evidence-based medicine (EBM) model has emerged. The practice of EBM requires new skills of the health care provider, including directed literature searches, the critical evaluation of research studies and the direct application of the findings to patient care.

Methods:
This paper describes the integration and evaluation of an evidence-based medicine course sequence into a Physician Assistant curriculum utilizing the expertise from faculty trained in basic science, nursing and primary care practice.

Results:
Collaboration of faculty with different educational backgrounds resulted in a course series that was equally strong in all aspects of EBM. This new course sequence teaches students to manage and use the best clinical research evidence to competently practice medicine. To assess the effectiveness of the EBM sequence a survey was developed and administered at the beginning and end of the sequence.

Conclusion:
EBM knowledge gained is essential to effective clinical decision making and this newly developed tool specifically helps to identify student competencies within the defined course objectives. Contributing to the uniqueness of the tool are case-based questions requiring integration of EBM knowledge by the student.
Familiarity and Screening Practices for Adverse Childhood Experiences
Authors: Vance Kyle , Budine Lexi , Craft Megan , Hahn Carter , Merz Nicole , Nave Charlsey , Woltenberg Leslie N 
Published: May 2021

Objective:
The purpose of this exploratory study was to examine adverse childhood experiences (ACEs), knowledge, and screening practices.

Methods:
A convenience sample of pediatric primary care providers in a health-care system within a high-prevalence state were invited to participate. The original 12-item survey addressed familiarity, tools, barriers, and prevalence regarding ACEs.

Results:
Study participants reported familiarity with ACEs; however, only 23% reported the use of any screening tool(s). Primary barriers included time and lack of staff and/or knowledge/training. About 77% of respondents have encountered at least eight of the 10 major types of ACEs. Most frequently encountered ACEs included parental separation or divorce, substance abuse in the household, and mental illness in the household. About 73% expressed interest in continuing medical education.

Conclusions:
Provider knowledge/familiarity with ACEs does not imply systematic screening. An efficient and evidence-based standardization for screening merits consideration. Continued education and training may address barriers to both provider understanding and screening of ACEs.
Qualitative Analysis of Student Responses to Survey Questions Investigating Student Perceptions of Case-Based Learning
Authors: Fogelberg Katherine , Simons Micha , Anderson Stacy 
Published: May 2021

Background:
This qualitative study applied discourse analysis to open ended question responses of fourth semester veterinary students enrolled in case based learning (CBL) course. This was the first CBL course incorporated into the curriculum and was delivered via teams of two professors for each of eight sessions.

Aims:
Questions were designed to investigate student perceptions of CBL and determine how it impacted their learning.

Results:
Results were reported to faculty to help them deliver high quality, engaging, and challenging CBL sessions that pushed students without being discouraging. From a cognition and learning perspective, students felt that CBL helped with learning at all levels of Bloom's taxonomy, encouraged metacognition, and helped prepare them for clinical rotations and postgraduation careers. From a mechanics and delivery perspective, students desired resources to help them use cases to learn about species in which they have a particular interest beyond the classroom; wanted interactive sessions and in class assessments, primarily involving individual responses using audience response software (clickers); enjoyed class and small group discussions; and preferred little to no out of classwork or assignments unless explicitly related to the case and expectations for the assignment(s) is/are clearly laid out.

Conclusions:
Overall, most students wanted more CBL and found it engaging, fun, and supportive of their learning.
Curriculum Mapping
Authors: Melody Karleen , Quinn Diane H , Waite Laura H , Mandos Laura A , Tietze Karen J 
Published: May 2021

Objective:
The objective of this study was to outline the process and results of a curriculum map revision.

Methods:
A revision process was developed for curricular competencies and measurable abilities (MAs). A crosswalk of the original MAs to the revised MAs and curriculum mapping reports for the 2018–2019 and 2019–2020 academic years were evaluated.

Results:
The number of competencies decreased from 12 to 11 and MAs increased from 90 to 98. The MA word count decreased from 1719 to 1498 (12.9%); 25 were combined, 26 were deleted, seven were divided, and 47 were created. Course learning outcomes (CLOs) mapped to a mean of 139 and 39 MAs prerevision and postrevision, respectively. Prerevision, 86.9% of CLOs mapped to an MA. Postrevision, 100% of CLOs mapped to an MA.

Conclusion:
Our revision process reduced redundancy and complexity and addressed gaps. Institutions searching for a model to assist with curriculum mapping and revisions may find our process useful.
Study of the effect of early and late acute rejection episodes on renal graft survival
Authors: Ragheb Ahmed , Kora Mahmoud A. Elaziz , Hassan Yassin F. , Kasem Heba E. 
Published: May 2021

Background
It has been demonstrated that acute rejection (AR) episodes are major risk factors of renal allograft loss. Still the impact of early acute rejection (EAR) on long-term graft survival is debated. The aim of this study was to study the impact of early acute rejection (EAR) and late acute rejection (LAR) on renal allograft survival.

Patients and methods
In this retrospective study we investigated the timing and frequency of AR episodes in 120 kidney transplant recipients for a 3-years period. Patients were divided into three groups; Group I: No acute rejection (No-AR), Group II: Early acute rejection (EAR), and Group III: Late acute rejection (LAR). The graft survivals in the three groups and the associated risk factors were analyzed.

Results
Of the 120 recipients one patient died (0.08%) and 14 grafts were lost (11.6%). The graft survival durations were 35.2, 23.6 and 27.2 months and the 3-years survival rates were 93%, 63.3% and 66.7% in the three groups respectively. The graft survival durations and rates were significantly higher in group I compared to groups II and III with no significant differences between the last two groups.

Conclusion
Both EAR and LAR have deleterious effects on graft survival following kidney transplantation.
Evaluation of cytomegalovirus prophylaxis regimens in renal transplant recipients as an economy-saving strategy
Authors: Abdel-Rahman Ahmed M. , Ibrahim Mohamed A. , Elmowafy Ahmed Y. , Gouda Tamer M. , Zahran Mahmoud H. , El-Okely Amir M. , Elsawy Essam , Saleh Hazem H. , Wafa Ehab W. 
Published: May 2021

Background
Variable prophylaxis regimens have been adapted to guard against cytomegalovirus (CMV) after renal transplantation. High-dose valganciclovir (VGCV) is the gold standard, but it is of very high cost. Herein, we compared another low-cost regimen [low-dose valacyclovir (VCV)] with low-dose VGCV to assess the efficacy and safety of VCV.

Patients and methods
This is a single-center randomized controlled trial that was held in Urology and Nephrology Center, Mansoura University, Egypt. The patients were divided into two groups according to CMV prophylaxis regimen used. Group I included 40 kidney transplant recipients who received low-dose VCV (2 g b.i.d.), and group II included 40 kidney transplant recipients who received low-dose VGCV (450 q.d.).

Results
Our patients’ age ranged from 18 to 58 years, and the majority were males. The median years of transplantation were 1.9 years. Efficacy of both regimens was similar. Interruption of VCV was more frequent, with significant difference, and it was associated with increased incidence of CMV infection but without any statistical significance. The cost of low-dose VGCV was very high in comparison with low-dose VCV.

Conclusion
Low-dose VCV showed the same efficacy and safety of low-dose VGCV as CMV prophylaxis protocol after kidney transplantation.
Plasma cortisol level and its relation to in-hospital mortality in acute kidney injury patients
Authors: Yousef Elshahat A. , El-Kannishy Sherif , Arfa Lamia F. , Mahmoud Rasha 
Published: May 2021

Background
Critically ill patients are at risk of developing critical illness-related corticosteroid insufficiency (CIRCI). This may present as hypotension, unresponsiveness to catecholamine infusions, and/or ventilator dependence. Acute kidney injury (AKI) usually complicates critically ill patients and is associated with hemodynamic instability. There is usually failure to predict the severity and to assess the response to therapy in AKI. The aim of this study was to assess the plasma cortisol level and its relation to hospital mortality in AKI patients.

Patients and methods
This is a prospective, observational study that included 66 patients with AKI admitted to the Dialysis and Nephrology Unit, Mansoura University Hospital, who were assessed clinically, followed by cortisol level assay done at the day of admission. Patients were followed clinically and biochemically till discharge. Patients were classified according to random plasma cortisol level into two groups: group 1 included 14 patients with random plasma cortisol of less than 10 μg/dl (CIRCI group) and group 2 included 52 patients with random plasma cortisol of greater than or equal to 10 μg/dl.

Results
There was a significant increase in platelet count in group 1 compared with group 2, while there was a significant decrease in serum potassium level in group 1 compared with group 2. Moreover, there was a significant decrease in urine output volume in group 1 compared with group 2 (P=0.03). Finally the hospital mortality rate was significantly higher in group 1 (CIRCI group) compared with group 2 (P=0.004).

Conclusion
AKI patients with low cortisol level at admission have higher mortality rate during the hospitalization period.
Potential medicinal plant remedies and their possible mechanisms against COVID-19: A review
Authors: Ugwah-Oguejiofor C.J. , Adebisi I.M. 
Published: May 2021

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak was first reported in Wuhan, a city in Hubei Province of China in December, 2019 and is known to be responsible for the novel coronavirus disease (COVID-19). COVID-19 was declared a pandemic in March, 2020 and since then, it has caused a number of deaths in over 200 countries around the world. Extensive researches have continued in the search of effective vaccines or drug compounds against SARS-CoV-2 and a total of 64 vaccines are currently in clinical trials with 12 currently approved for use by different regulatory bodies, depending on the country. Since the outbreak of SARS-CoV-2, many countries have utilised traditional herbal medicines alongside conventional drugs for the treatment of infected patients. In this review, traditional medicines used to prevent or treat SARS-CoV-2 infection are listed along with the plant parts as used by the traditional healers. Additionally, the possible mechanisms responsible for this preventive or therapeutic outcome are also identified and listed. Our literature search was conducted using Google Scholar, PubMed, Scopus and WHO website. Unpublished reports such asdissertations and theses are not included. Plant parts including roots, leaves, flowers, seeds and so on have been used in the treatment of COVID-19. These traditional medicinal herbs may exert their anti-COVID-19 activity by direct inhibition of the virus replication or entry. Some may act by blocking the ACE-2 receptor, SARS-CoV helicase, Type II Transmembrane Serine Protease (TMPRSS2) and which are required by SARS-CoV-2 in order to infect human cells. Others act by inhibiting the SARSCoV-2 life-cycle related proteins, namely chymotrypsin-like cysteine protease (3CL-pro) and Papain-like protease (PL-pro). Medicinal plants are promising alternative medicines for the treatment or prevention of SARS-CoV-2 infection. Further researches, are needed to decipher their active components and structures which may suggest clues for the development of drugs against this novel coronavirus.
Keywords: Severe Acute Respiratory Syndrome (SARS-CoV-2), COVID-19, medicinal plants, plant parts, mechanism of action, pandemic,
Impact of doubling the recommended dose of Magicforce (Lambda-Cyhalothrin + Dimethoate) on major associated arthropods and performance of watermelon
Authors: Okrikata E. , Agere H. , Adepoju I.O. , Malu S.P. 
Published: May 2021

Some crop growers hold the view that application of pesticides at higher than the manufacturer's recommended doses results in better pest control and crop productivity. The veracity of this perception was evaluated in field experiments at the experimental field of Federal University Wukari. A recommended insecticide and acaricide; ® Magicforce (Lambda-cyhalothrin 15g/L + Dimethoate 300 g/L) was evaluated against insect pests of watermelon (Citrullus lanatus Thunb.) and other associated beneficial arthropods. The experiments were laid in a Randomized Complete Block Design with five treatments (control inclusive). Data collected includes arthropod (pest and beneficial) densities, crop growth, and number of fruits at the early-fruiting stage which were analyzed using variance analysis after appropriate transformations. Student's t-test was used to compare early- and lateseason's variables while correlation and regression analyses were used to determine relationships between key variables. Results showed that plots treated with double the highest manufacturer's recommended dose of ® Magicforce (cost implication of ₦ 144,000) had lower pest (leaf beetle species and Bactrocera cucurbitae) and beneficial arthropod (predatory ants, spiders and Apis mellifera) densities than those treated with the lowest (cost – ₦ 48,000) and highest (cost – ₦ 72,000) recommended doses. Their plant growth (vine length and number of leaves) and fruit production were however comparatively lower though largely statistically comparable. The ® relationship between the quantity of Magicforce applied and number of fruits produced were though positive, 2 2 only moderate and insignificant in both early- (r = 0.665, R = 44.3%, p = 0.220) and late- (r = 0.659, R = 43.4%, p = 0.227) crops. The results revealed that the application of double the manufacturer's recommended dose of ® Magicforce (with its comparatively higher cost implication of 100 – 200%) suppressed growth of watermelon by 1.96 – 6.20%, and impeded fruit production by 9.14 – 13.30%. While there is need to verify the mechanism of this key finding, the need to source for genuine pesticides and follow manufacturer's recommended doses a re highlighted.
Keywords: Arthropods, Insect pests, Organophosphate, Pesticide over-dose, Pyrethroid, Watermelon
GC-MS analyses of young and mature Archidium Ohioense Schimp Ex. C. Mull and Philonotis hastate (Duby) Wijk & Margad extracts
Authors: Isa M.O. , Akinpelu B.A. , Makinde A.M. 
Published: May 2021

Analyses of the constituents of the crude extracts obtained from young and mature moss species namely: Archidium ohioense and Philonotis hastata were conducted with a view to investigating the effects of maturity stages on their bioactive constituents. The mosses collected from their natural population were air dried at ambient temperature in the laboratory, extracted with methanol and the crude extracts subjected to gas chromatographymass spectrometry (GC-MS) analysis. The results of the analyses showed the presence of 20 compounds in young A. ohioense with n-hexadecanoic acid [26.60%], bis(2-ethylhexyl) phthalate [12.47%], bicyclo (3.1.1)heptane 2,6,6-trimethyl-[1r-(1.alpha.,2.beta.,5.alpha.)]- [11.59%] and phytol [9.69%] forming the prominent components while in the mature A. ohioense, 13 compounds were present, from which n-hexadecanoic acid [51.25%], hexadecanoic acid 2-hydroxy-1-(hydroxymethyl)-ethyl ester [9.90%] and n-propyl 9-octadecenoate [7.47%] formed the prominent components. In P. hastata, 20 compounds were identified in the young stage sample with n-hexadecanoic acid [22.46%], bis(2-ethylhexyl) phthalate [20.95%] and phytol [18.14%] as the prominent components while 9 compounds were identified in the mature sample with n-hexadecanoic acid[51.84%], hexadecanoic acid 2-hydroxy-1-(hydroxymethyl)ethyl ester [18.12%] and bis(2-ethylhexyl) phthalate [9.11%] which formed the prominent components. The study indicated that, maturity stages at collection of the mosses affected their bioactive compositions, with the young stage mosses showing more bioactive compounds than the mature ones.
Keywords: A. ohioense, P. hastata, Mosses, Maturity stages, Crude extract, GC-MS.
TÁC ĐỘNG PHỐI HỢP CỦA UNTI-K VÀ NANOCURCUMIN TRONG QUÁ TRÌNH PHÒNG VÀ CHỮA TRỊ UNG THƯ VÚ TRÊN CHUỘT
Authors: THỊ PHƯƠNG NHUNG TRẦN , TRƯỜNG SƠN NGUYỄN , THỊ MỸ ÚC TRƯƠNG , THỊ KIM TRINH NGUYỄN , THỊ ÁNH TUYẾT VŨ , VŨ LINH NGUYỄN , THỊ TRÚC LINH TRẦN , THANH HIẾU HỒ , QUỐC NGUYÊN NGUYỄN , NGỌC BẢO TRÂN NGUYỄN , THỊ DIỄM ĐINH , DUY KHANG LÊ , THỊ YẾN NHI NGUYỄN 
Published: May 2021

Ung thư vú - bệnh lý ác tính, phát triển từ biểu mô tuyến vú. Khi bị kích thích bởi tác nhân sinh ung thư, tế bào tuyến vú tăng sinh vô hạn độ, vô tổ chức, hình thành khối u. Unti-K - dược liệu được sản xuất từ thảo dược thiên nhiên gồm bột tam thất, cao khô phylamin, cao khô xạ đen, cao tỏi đen, cao trinh nữ hoàng cung,… chứa các saponin, flavonoid, S-allyl-L-Cystein, alkaloid … gây độc tế bào ung thư, gây alkyl hóa nucleotide, cản trở DNA sao chép, trì hoãn di căn. Nanocurcumin giúp ngừng tân tạo mạch, hoạt hóa protein kháng ung thư. Tinh chất curcumin được bảo vệ khi gắn kết với nano, dễ di chuyển và không bị hao tổn trên đường đi đến tế bào đích. Trong nghiên cứu này chúng tôi đã xây dựng mô hình phòng và chữa trị ung thư vú (DMBA gây ung thư vú) nhờ tác động cộng gộp của unti-k với nanocurcumin trên chuột (Mus musculus var. Albino). Sau 40 tuần phòng và chữa bệnh, các chỉ số về trọng lượng cơ thể, lượng bạch cầu trong máu chuột bị bệnh dần trở về mức bình thường. Hiệu quả phối hợp của unti-k và nanocucumin đối với việc giảm thể tích khối u đã được chứng minh. Phân tích mô học cho thấy việc phối hợp unti-k và nanocurcumin đã ức chế sự xâm nhập tế bào ung thư biểu mô tuyến vú ở mô xung quanh, việc xâm lấn mô mỡ, mô đệm tuyến vú đã bị kìm hãm, mô tiểu thùy bị hoại tử dần hồi phục trở lại. Như vậy, sự phối hợp unti-k và nanocurcumin tạo hạt tiểu phân kích thước siêu nhỏ, giúp hấp thu nhanh vào máu, tăng lượng tế bào lympho T, hồi phục hệ thống miễn dịch, ngăn chặn tăng sinh, ức chế di căn, đẩy nhanh sự chết của tế bào ung thư.
CURRENT CONTAMINATION OF PERSISTENT ORGANOCHLORINES IN THIVAI RIVER SEDIMENTS, SOUTHERN VIETNAM
Authors: NGUYEN NGOC VINH , DE ALENCASTRO LUIZ FELIPPE 
Published: May 2021

This report presents the development an highly sensitive, stable and reliable OCs analyzing method with GC/MS (gas chromatography/mass spectrometry) and results of OCs (organochlorines) levels in sediments of Thivai River basin. The method recovery ranges from 72% to 129% and meets the requirement for OCs analyzing. 18 composite sediment samples were taken from 18 sites along Thivai river basin from upstream (Formosa Plant sewer mouth – Lo Ren canal) to downstream (confluence of Thi Vai and Go Gia rivers). The analytical results show that OCs concentration in Thi Vai river sediment (max 1.73 ng/g dry weight) is not higher than those of the reference sites and other river basins in Vietnam and in the world.