bluuebunny/crossref_metadata_2025_split huggingface dataset:
Photobiomodulation enhances facial nerve regeneration via activation of PI3K/Akt signaling pathway–mediated antioxidant response
Authors: Li Bohan , Wang Xiao 
Published: July 2021

AbstractFacial nerve dysfunction is a common clinical condition that leads to disfigurement and emotional distress in the affected individuals. This study aimed to evaluate whether photobiomodulation can enhance regeneration of crushed facial nerves and attempt to investigate the possible underlying mechanism of neuroprotective function and therapeutic target. Various parameters of photobiomodulation were assigned to the facial nerves and Schwann cells (SCs) separately during crushed injury in rats. Axonal regeneration, functional outcomes, and SC apoptosis, proliferation, and underlying mechanisms of action were evaluated by morphological, histopathological, and functional assessments, flow cytometry, western blotting, real-time PCR, and IncuCyte. The results showed that photobiomodulation improved axonal regeneration and functional recovery, and also promoted proliferation, and inhibited apoptosis of SCs, both of these were considered as the most effective parameters in 250mW group. In addition, the neuroprotective effects of photobiomodulation (500mW) were likely associated with oxidative stress–induced SC apoptosis via activation of the PI3K/Akt signaling pathway. Our results revealed that photobiomodulation significantly promoted axonal regeneration, functional recovery, and regeneration of the facial nucleus, and its mechanism was related to the up-regulation of the PI3K/Akt signaling pathway. These findings provide clear experimental evidence of photobiomodulation as an alternative therapeutic strategy for peripheral nerve damage.
Architectural model for muscle growth during maturation
Authors: Papenkort Stefan , Böl Markus , Siebert Tobias 
Published: July 2021

AbstractMuscle architecture, which includes parameters like fascicle length, pennation angle, and physiological cross-sectional area, strongly influences skeletal muscles' mechanical properties. During maturation, the muscle architecture has to adapt to a growing organism. This study aimed to develop an architectural model capable of predicting the complete 3D fascicle architecture for primarily unipennate muscles of an arbitrary age, based on fascicle data for an initial age. For model development, we collected novel data on 3D muscle architecture of the rabbit (Oryctolagus cuniculus) M. plantaris of eight animals ranging in age from 29 to 106 days. Experimental results show that plantaris muscle belly length increases by 73%, whereas mean fascicle length and mean pennation angle increases by 39 and 14%, respectively. Those changes were incorporated into the model. In addition to the data collected for M. plantaris the predictions of the model were compared to existing literature data of rabbit M. soleus and M. gastrocnemius medialis. With an error of −1.0 ± 8.6% for relative differences in aponeurosis length, aponeurosis width, muscle height, and muscle mass, the model delivered good results matching interindividual differences. For future studies, the model could be utilized to generate realistic architectural data sets for simulation studies.
Examining HIV Risk and Exchange Sex Among Current and Formerly Homeless Young Adults
Authors: Madden Danielle R. , Semborski Sara , Dzubur Eldin , Redline Brian , Rhoades Harmony , Henwood Benjamin F. 
Published: July 2021

AbstractThis study investigated HIV risk among homeless and formerly homeless young adults by examining risky sex behaviors (e.g., condomless sex, exchange sex, and sex with multiple persons) using 90-day and daily recall methods. Data came from a sample of young adults (aged 18–27) with current (n = 101) or past (n = 109) homelessness experience in Los Angeles, California, recruited between 2017 and 2019. Baseline surveys queried demographics and sexual history. Daily retrospective surveys queried sexual events. Multiple logistic regressions were used to test the effects of demographic characteristics including homelessness history, relationship status, substance use, and sexual history on risky sex outcomes. In this sample, 26% reported never using a condom during anal or vaginal sex in the past 90 days, 5% reported testing positive for HIV, 82% had limited to no knowledge of preexposure prophylaxis, and 8% reported having had exchange sex during a 7-day measurement period, with those experiencing homelessness more likely to report. The study suggests supportive housing can reduce the occurrence of exchange sex but that HIV prevention services are still needed in homeless and housing programs to promote safe sexual practices.
Horizontal convection in a rectangular enclosure driven by a linear temperature profile
Authors: Yang Tianyong , Wang Bofu , Wu Jianzhao , Lu Zhiming , Zhou Quan 
Published: July 2021

AbstractThe horizontal convection in a square enclosure driven by a linear temperature profile along the bottom boundary is investigated numerically by using a finite difference method. The Prandtl number is fixed at 4.38, and the Rayleigh number Ra ranges from 107 to 1011. The convective flow is steady at a relatively low Rayleigh number, and no thermal plume is observed, whereas it transits to be unsteady when the Rayleigh number increases beyond the critical value. The scaling law for the Nusselt number Nu changes from Rossby’s scaling Nu ∼ Ra1/5 in a steady regime to Nu ∼ Ra1/4 in an unsteady regime, which agrees well with the theoretically predicted results. Accordingly, the Reynolds number Re scaling varies from Re ∼ Ra3/11 to Re ∼ Ra2/5. The investigation on the mean flows shows that the thermal and kinetic boundary layer thickness and the mean temperature in the bulk zone decrease with the increasing Ra. The intensity of fluctuating velocity increases with the increasing Ra.
Typical transient effects in a piezoelectric semiconductor nanofiber under a suddenly applied axial time-dependent force
Authors: Yang Wanli , Liang Yuxing 
Published: July 2021

AbstractBased on the mechanical motion equation, Gauss’s law, and the current continuity condition, we study a few typical transient effects in a piezoelectric semiconductor (PS) fiber to realize the startup and turning-off functions of common piezotronic devices. In this study, the transient extensional vibration induced by a suddenly applied axial time-dependent force is examined in a cantilevered n-type ZnO nanofiber. Neither the magnitude of the loadings nor the doping concentration significantly affects the propagation caused by disturbance of the axial displacement. However, both of the factors play an important role in the propagation caused by disturbance of the electron concentrations. This indicates that the electromechanical coupling effect can be expected to directly determine the electronic performance of the devices. In addition, the assumption of previous simplified models which neglect the charge carriers in Gauss’s law is discussed, showing that this assumption has a little influence on the startup state when the doping concentration is smaller than 1021 m−3. This suggests that the screening effect of the carriers on the polarized electric field is much reduced in this situation, and that the state is gradually transforming into a pure piezoelectric state. Nevertheless, the carriers can provide a damping effect, which means that the previous simplified models do not sufficiently describe the turning-off state. The numerical results show that the present study has referential value with respect to the design of newly multifunctional PS devices.
Challenges and Paradoxes in Decolonising HCI: A Critical Discussion
Authors: Lazem Shaimaa , Giglitto Danilo , Nkwo Makuochi Samuel , Mthoko Hafeni , Upani Jessica , Peters Anicia 
Published: July 2021

AbstractThe preponderance of Western methods, practices, standards, and classifications in the manner in which new technology-related knowledge is created and globalised has led to calls for more inclusive approaches to design. A decolonisation project is concerned with how researchers might contribute to dismantling and re-envisioning existing power relations, resisting past biases, and balancing Western heavy influences in technology design by foregrounding the authentic voices of the indigenous people in the entire design process. We examine how the establishment of local Global South HCI communities (AfriCHI and ArabHCI) has led to the enactment of decolonisation practices. Specifically, we seek to uncover how decolonisation is perceived in the AfriCHI and ArabHCI communities as well as the extent to which both communities are engaged with the idea of decolonisation without necessarily using the term. We drew from the relevant literature, our own outsider/insider lived experiences, and the communities’ responses to an online anonymised survey to highlight three problematic but interrelated practical paradoxes: a terminology, an ethical, and a micro-colonisation paradox. We argue that these paradoxes expose the dilemmas faced by local non-Western researchers as they pursue decolonisation thinking. This article offers a blended perspective on the decolonisation debate in HCI, CSCW, and the practice-based CSCW scholarly communities and invites researchers to examine their research work using a decolonisation lens.
(Mere) Verbalness and Substantivity Revisited
Authors: Knoll Viktoria 
Published: July 2021

AbstractVerbal disputes are often seen as closely related to a lack of substantivity. However, a systematic and comprehensive investigation of how verbalness relates to substantivity is still missing. The present paper attempts to close this gap. In addition to offering different conceptions of verbalness, the paper further develops Sider’s (Writing the Book of the World, OUP, Oxford, 2011) notion of substantivity. Ultimately, I argue for a more careful choice of terminology when it comes to assessing a dispute as “(merely) verbal” or “nonsubstantive”. While the paper shows that there is no strict logical relation between mere verbalness and nonsubstantivity construed along the lines set out by Sider, it also demonstrates that further notable notions of (mere) verbalness and substantivity are in fact closely intertwined.
Application of Big Data and Artificial Intelligence in COVID-19 Prevention, Diagnosis, Treatment and Management Decisions in China
Authors: Dong Jiancheng , Wu Huiqun , Zhou Dong , Li Kaixiang , Zhang Yuanpeng , Ji Hanzhen , Tong Zhuang , Lou Shuai , Liu Zhangsuo 
Published: July 2021

AbstractCOVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread rapidly and affected most of the world since its outbreak in Wuhan, China, which presents a major challenge to the emergency response mechanism for sudden public health events and epidemic prevention and control in all countries. In the face of the severe situation of epidemic prevention and control and the arduous task of social management, the tremendous power of science and technology in prevention and control has emerged. The new generation of information technology, represented by big data and artificial intelligence (AI) technology, has been widely used in the prevention, diagnosis, treatment and management of COVID-19 as an important basic support. Although the technology has developed, there are still challenges with respect to epidemic surveillance, accurate prevention and control, effective diagnosis and treatment, and timely judgement. The prevention and control of sudden infectious diseases usually depend on the control of infection sources, interruption of transmission channels and vaccine development. Big data and AI are effective technologies to identify the source of infection and have an irreplaceable role in distinguishing close contacts and suspicious populations. Advanced computational analysis is beneficial to accelerate the speed of vaccine research and development and to improve the quality of vaccines. AI provides support in automatically processing relevant data from medical images and clinical features, tests and examination findings; predicting disease progression and prognosis; and even recommending treatment plans and strategies. This paper reviews the application of big data and AI in the COVID-19 prevention, diagnosis, treatment and management decisions in China to explain how to apply big data and AI technology to address the common problems in the COVID-19 pandemic. Although the findings regarding the application of big data and AI technologies in sudden public health events lack validation of repeatability and universality, current studies in China have shown that the application of big data and AI is feasible in response to the COVID-19 pandemic. These studies concluded that the application of big data and AI technology can contribute to prevention, diagnosis, treatment and management decision making regarding sudden public health events in the future.
Environmental and economic analysis of bioethanol production from sugarcane molasses and agave juice
Authors: Parascanu Maria Magdalena , Sanchez Nestor , Sandoval-Salas Fabiola , Carreto Carlos Mendez , Soreanu Gabriela , Sanchez-Silva Luz 
Published: July 2021

AbstractIn this article, sugarcane molasses and agave juice were compared as potential feedstocks for producing bioethanol in Mexico in terms of their environmental impact and economic factors. Life cycle assessment (LCA) using SimaPro was carried out to calculate environmental impacts by using a cradle-to-gate approach. A preliminary economic analysis was performed to determine the economic feasibility of the studied options. Also, capital goods costs were obtained using the Aspen Plus economy package. Moreover, a sensitivity analysis was involved to compare the environmental and economic viability of producing bioethanol from sugarcane molasses and agave juice. LCA results revealed that cultivation and fermentation were the most harmful stages when producing bioethanol from sugarcane molasses and agave juice, respectively. Furthermore, when it was derived from agave juice rather than sugarcane molasses, it had more environmental benefits. This was ascribed to the lower consumption rate of fertilizers, pesticides, and emissions given off from the former. Regarding financial aspects, the preliminary analysis showed that producing bioethanol was not economically viable when grid energy alone was used. However, if power from the grid is partially replaced with renewable energy, producing bioethanol becomes economically feasible, and sugarcane molasses is the most suitable feedstock.
Graphical abstract
Characterization of black crusts developed on historic stones with diverse mineralogy under different air quality environments
Authors: Pozo-Antonio José Santiago , Cardell Carolina , Comite Valeria , Fermo Paola 
Published: July 2021

AbstractBlack crusts (BCs) are one of the most critical alteration forms found on stones belonging to architectural heritage. Since they could be considered as passive samplers of atmospheric pollution, it would be plausible to establish relations between the air contamination and the BCs. With this aim, we have characterized BCs collected on historic buildings from two Spanish cities (Granada and Vigo) with different polluted atmospheres, as well as formed on stone substrates of varied mineralogy and texture. Likewise, in order to assess the impact of the atmospheric pollutants on the growth of BCs, quartz fiber filters were used as surrogate substrates and placed nearby the studied buildings to collect and analyze the aerosol particulate matter (PM). To this end, an array of complementary analytical techniques was used to evaluate the mineralogy, chemical composition, and texture of the BCs and to establish the correlation with the ions, OC (organic carbon), and EC (elemental carbon) detected in the PM on the quartz fiber filters. As result, BCs developed on carbonate substrates from Granada show more complex structure than those from Vigo, which are thinner because of frequent rain episodes. In both cities, NaCl, Pb-Cl, and Ca-Cl-rich particles, Ca-phosphate particles and clusters of Ba-sulfate-rich particles were detected. However, metal-rich rounded particles were more abundant in Granada’s BCs, including soot particles. BCs from Granada were richer in carbonaceous components (OC and EC) than the Vigo’s BCs. Although in the filters PM did not show EC—mainly due to traffic—, in the BCs from both locations OC and EC were detected. Therefore, this different composition was related to the mineralogy of the stones and the higher pollution of Granada in contrast to the industrial and sea-exposed city of Vigo.
The Potato of the Future: Opportunities and Challenges in Sustainable Agri-food Systems
Authors: Devaux André , Goffart Jean-Pierre , Kromann Peter , Andrade-Piedra Jorge , Polar Vivian , Hareau Guy 
Published: July 2021

AbstractIn the coming decades, feeding the expanded global population nutritiously and sustainably will require substantial improvements to the global food system worldwide. The main challenge will be how to produce more food with the same or fewer resources and waste less. Food security has four dimensions: food availability, food access, food use and quality, and food stability. Among several other food sources, the potato crop is one that can help match all these constraints worldwide due to its highly diverse distribution pattern, and its current cultivation and demand, particularly in developing countries with high levels of poverty, hunger, and malnutrition. After an overview of the current situation of global hunger, food security, and agricultural growth, followed by a review of the importance of the potato in the current global food system and its role played as a food security crop, this paper analyses and discusses how potato research and innovation can contribute to sustainable agri-food systems comparing rural and industrial agri-food systems with reference to food security indicators. It concludes with a discussion about the challenges for sustainable potato cropping enhancement considering the needs to increase productivity in rural-based potato food systems that predominate in low-income countries, while promoting better resource management and optimization in industrial-based agri-food systems considering factors such as quality, diversity of products, health impacts, and climate change effects. Research and innovation options and policies that could facilitate the requirements of both rural and industrial potato-based agri-food systems are described.
Objective assessment of surgeon kinematics during simulated laparoscopic surgery: a preliminary evaluation of the effect of high body mass index models
Authors: Sers Ryan , Forrester Steph , Zecca Massimiliano , Ward Stephen , Moss Esther 
Published: July 2021

Abstract
Purpose
Laparoscopy is used in many surgical specialties. Subjective reports have suggested that performing laparoscopic surgery in patients with a high body mass index (BMI) is leading to increased prevalence of musculoskeletal symptoms in surgeons. The aim of this study was to objectively quantify the impact on surgeon upper body kinematics and dynamic workload when performing simulated laparoscopy at different BMI levels.

Methods
Upper body kinematics and dynamic workload of novice, intermediate and expert surgeons were calculated based on measurements from inertial measurement units positioned on upper body segments. Varying thicknesses of foam were used to simulate patient BMIs of 20, 30, 40 and 50 kg/m2 during laparoscopic training.

Results
Significant increases in the jerkiness, angular speed and cumulative displacement of the head, torso and upper arms were found within all experience groups when subject to the 40 and 50 kg/m2 models. Novice surgeons were found to have less controlled kinematics and larger dynamic workloads compared to the more experienced surgeons.

Conclusions
Our findings indicate that performing laparoscopic surgery on a high BMI model worsens upper body motion efficiency and efficacy, and increases dynamic workload, producing conditions that are more physically demanding when compared to operating on a 20 kg/m2 model. These findings also suggest that the head, torso, and upper arm segments are especially affected by high BMI models and therefore exposure to patients with high BMIs may increase the risk of musculoskeletal injury when performing laparoscopic surgery.
Harming, Rescuing and the Necessity Constraint on Defensive Force
Authors: Fabre Cécile 
Published: July 2021

AbstractIn The Morality of Defensive Force, Quong defends a powerful account of the grounds and conditions under which an agent may justifiably inflict serious harm on another person. In this paper, I examine Quong's account of the necessity constraint on permissible harming—the RESCUE account. I argue that RESCUE does not succeed. Section 2 describes RESCUE. Section 3 raises some worries about Quong's conceptual construal of the right to be rescued and its attendant duties. Section 4 argues that RESCUE does not deliver the verdicts that Quong wants. In those sections, I assume that the attacker is culpable for the threat he poses. Section 5 considers cases where the attacker, though responsible for the wrongful threat he poses and therefore liable to defensive force, has an epistemic justification for acting as he does and thus is not morally culpable. In his discussion of necessity, Quong does not explicitly deal with such cases. I suggest that RESCUE does not operate in the same way when attackers are mistaken as when they are morally culpable.
Impact of Surface Topography, Chemistry and Properties on the Adhesion of Sodium Alginate Coatings Electrophoretically Deposited on Titanium Biomaterials
Authors: Warcaba Maciej , Kowalski Kazimierz , Kopia Agnieszka , Moskalewicz Tomasz 
Published: July 2021

Abstract
In this paper, we report on the electrophoretic deposition and characterisation of pure sodium alginate coatings on titanium biomaterials, the commercially pure titanium CP-Ti1 and Ti–13Nb–13Zr titanium alloy. Various solutions differing in the distilled water to ethanol volume ratio and sodium alginate concentration were used for coating deposition. Uniform, dense and continuous coatings with a thickness up to 1 µm were deposited. The effect of surface topography and morphology, wettability and surface free energy as well as surface chemistry on the coating adhesion to the titanium biomaterials were investigated. The coatings exhibited very good adhesion to the polished and then chemically treated alloy. The adhesion mechanisms were identified. The chemical bonding and interfacial adhesion mechanisms are plausible. The coatings exhibited low surface development, dependent on the applied substrate roughness. Sodium alginate coatings on both substrates showed moderate hydrophilicity and relatively high surface free energy, on average 30 pct higher in comparison with that of the substrate materials. The obtained results will be useful for the further development of composite sodium alginate coatings for enhancing the biological performance of titanium biomaterials.