bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychosocial Long-Term Effects of Young Adult Cancer Survivors: Study Protocol of the Longitudinal AYA-LE Long-Term Effects Study
Authors: Geue Kristina , Mehnert-Theuerkauf Anja , Stroske Isabelle , Brock Hannah , Friedrich Michael , Leuteritz Katja 
Published: September 2021

Background:About 3% of new cancer cases affect young adults aged between 15 and 39 years. The young age, the increasing incidence and the relatively good prognosis of this population lead to the growing importance to investigate the psychosocial long-term and late effects. The aims of the AYA-LE long-term effects study are: first, to assess the temporal course and related factors of life satisfaction and psychological distress of adolescent and young adult (AYA) cancer survivors; and second, to examine a specific topic in each of the yearly surveys in a more differentiated way.Methods:This study represents a continuation of the longitudinal AYA-LE study. The existing sample of AYA cancer patients (t1:N= 577; t2:N= 514; aged between 18 and 39 years at diagnosis; all major tumor entities) was extended by four further survey points (t3: 2018, t4: 2019, t5: 2020, t6: 2021). In addition, a comparison sample of young adults without cancer was collected. We measured longitudinal data for outcomes such as quality of life, psychological distress, and fatigue with standardized questionnaires. Furthermore, each survey point included a different cross-sectional topic (e.g., health behavior, occupational situation, and compliance).Discussion:The AYA-LE long-term effects study will show the long-term consequences of cancer in young adulthood. We expect at least complete data of 320 participants to be available after the sixth survey, which will be completed in 2021. This will provide a comprehensive and differentiated understanding of the life situation of young adults with cancer in Germany. The findings of our study enable a continuous improvement of the psychosocial care and specific survivorship programs for young cancer patients.
Negotiating System Requirements to Secure Client Engagement – Therapist Strategies in Adolescent Psychotherapy Initiated by Others
Authors: Stige Signe Hjelen , Eik Ingrid , Oddli Hanne Weie , Moltu Christian 
Published: September 2021

Background: Many adolescent clients come to treatment reluctantly, at the initiative of others. Adolescents also quit therapy prematurely more often than adult clients do. This points to the value of finding good ways to engage adolescent clients in treatment and understanding more of what therapists do to achieve this task.Methods: We used focus group methodology to explore therapist strategies and behaviors to engage adolescent clients who come to therapy at the initiative of others. Ten focus group interviews with a total of 51 therapists were conducted with existing treatment teams from seven different clinics in community mental health care for children and youth. Reflexive thematic analysis was used as a framework to guide the analytical process.Findings: Navigating a position allowing the therapist and adolescent to meet and work toward a shared understanding of the situation and what could help was considered the main gateway to client engagement. To do this, therapists had to manage the pull between system requirements and their obligation to the individual adolescent client, represented by the theme Managing system requirements. The process of working with the adolescent to ensure engagement is represented by the four themes: Counteracting initial obstacles for client engagement – “You are not trapped here”; Sharing definitional power – “What does it look like to you?”; Practicing transparency – “I want you to know what I see”; and Tailoring as ideal – “I will design this therapy for you.”Implication and conclusion: Therapists want to understand their adolescent clients’ position better, and subsequently adjust the treatment goals and techniques to establish sufficient common ground to allow both the therapist and adolescent to find the therapeutic project worthwhile. However, system requirements and service organization were found to obstruct and influence these processes in several ways, pointing to the significance of exploring the interplay between system organization and therapeutic practice more thoroughly. There was also a variation between therapist behaviors described by different therapists within the same treatment teams, as well as systematic differences between treatment teams, pointing to the importance of future research differentiating wanted from unwanted variation in treatment.
Universal Transceivers: Opportunities and Future Directions for the Internet of Everything (IoE)
Authors: Civas Meltem , Cetinkaya Oktay , Kuscu Murat , Akan Ozgur B. 
Published: September 2021

The Internet of Everything (IoE) is a recently introduced information and communication technology (ICT) framework promising for extending the human connectivity to the entire universe, which itself can be regarded as a natural IoE, an interconnected network of everything we perceive. The countless number of opportunities that can be enabled by IoE through a blend of heterogeneous ICT technologies across different scales and environments and a seamless interface with the natural IoE impose several fundamental challenges, such as interoperability, ubiquitous connectivity, energy efficiency, and miniaturization. The key to address these challenges is to advance our communication technology to match the multi-scale, multi-modal, and dynamic features of the natural IoE. To this end, we introduce a new communication device concept, namely the universal IoE transceiver, that encompasses transceiver architectures that are characterized by multi-modality in communication (with modalities such as molecular, RF/THz, optical and acoustic) and in energy harvesting (with modalities such as mechanical, solar, biochemical), modularity, tunability, and scalability. Focusing on these fundamental traits, we provide an overview of the opportunities that can be opened up by micro/nanoscale universal transceiver architectures towards realizing the IoE applications. We also discuss the most pressing challenges in implementing such transceivers and briefly review the open research directions. Our discussion is particularly focused on the opportunities and challenges pertaining to the IoE physical layer, which can enable the efficient and effective design of higher-level techniques. We believe that such universal transceivers can pave the way for seamless connection and communication with the universe at a deeper level and pioneer the construction of the forthcoming IoE landscape.Index Terms– Internet of Everything, Universal IoE Transceiver, Interoperability, Multi-modality, Hybrid Energy Harvesting, Molecular Communications, THz Communications, Graphene and related nanomaterials.
Robotic Cochlear Implant Surgery: Imaging-Based Evaluation of Feasibility in Clinical Routine
Authors: Auinger Alice Barbara , Dahm Valerie , Liepins Rudolfs , Riss Dominik , Baumgartner Wolf-Dieter , Arnoldner Christoph 
Published: September 2021

Background: Robotic surgery has been proposed in various surgical fields to reduce recovery time, scarring, and to improve patients' outcomes. Such innovations are ever-growing and have now reached the field of cochlear implantation. To implement robotic ear surgery in routine, it is of interest if preoperative planning of a safe trajectory to the middle ear is possible with clinically available image data.Methods: We evaluated the feasibility of robotic cochlear implant surgery in 50 patients (100 ears) scheduled for routine cochlear implant procedures based on clinically available imaging. The primary objective was to assess if available high-resolution computed tomography or cone beam tomography imaging is sufficient for planning a trajectory by an otological software. Secondary objectives were to assess the feasibility of cochlear implant surgery with a drill bit diameter of 1.8 mm, which is the currently used as a standard drill bit. Furthermore, it was evaluated if feasibility of robotic surgery could be increased when using smaller drill bit sizes. Cochlear and trajectory parameters of successfully planned ears were collected. Measurements were carried out by two observers and the interrater reliability was assessed using Cohen's Kappa.Results: Under the prerequisite of the available image data being sufficient for the planning of the procedure, up to two thirds of ears were eligible for robotic cochlear implant surgery with the standard drill bit size of 1.8 mm. The main reason for inability to plan the keyhole access was insufficient image resolution causing anatomical landmarks not being accurately identified. Although currently not applicable in robotic cochlear implantation, narrower drill bit sizes ranging from 1.0 to 1.7 mm in diameter could increase feasibility up to 100%. The interrater agreement between the two observers was good for this data set.Discussion: For robotic cochlear implant surgery, imaging with sufficient resolution is essential for preoperative assessment. A slice thickness of &lt;0.3 mm is necessary for trajectory planning. This can be achieved by using digital volume tomography while radiation exposure can be kept to a minimum. Furthermore, surgeons who use the software tool, should be trained on a regular basis in order to achieve planning consistency.
Photocatalytic Degradation of Diazo Dye over Suspended and Immobilized TiO2 Catalyst in Swirl Flow Reactor: Kinetic Modeling
Authors: Jadaa Waleed , Prakash Anand , Ray Ajay K. 
Published: September 2021

The degradation kinetics of Direct Blue 15 (DB15), a diazo dye, were studied over a suspended and immobilized TiO2 catalyst. For all experiments, the kinetics experiments were performed in a swirl flow photoreactor under the influence of UV light. The effect of different parameters: dye concentration, catalyst loading, and light intensity, on the DB15 kinetics was investigated. The kinetic rates were assessed using apparent (ka) approach, a single value of reaction rate (kr) and adsorption constant (K), and approach of kr as of variable. The DB15 mineralization was discussed as well. Using a dip-coating device, the P25 catalyst was deposited on a Pyrex glass. The thin film surface characterization was examined. The coated catalyst was evaluated by checking the effect of two variables: initial dye concentration and light intensity on the DB15 kinetics. In terms of the ka approach, the results demonstrated that DB15 degradation is described by the pseudo first-order kinetics model. The Langmuir-Hinshelwood (L-H) model was fitted well with the experimental data for the number of process variables. L-H constant kr was determined as a function of three parameters: initial dye concentration, catalyst loading, and light intensity. The ka values were evaluated and compared with experimental results. In terms of three variables, ka can be expressed as ka=0.15 [C]o−0.69 [W]0.73 I0.91 1+0.17 [C]o while the empirical model results in the following expression, ka=0.77 [C]o−1.65 [W]0.73 Io0.89. It was observed that 83.64% mineralization was achieved after a period of 16 hrs. In terms of immobilized catalyst, the DB15 degradation kinetics was described by a pseudo first-order model for different dye concentrations. Meanwhile, a power-law model described the impact of light intensity on dye kinetics. In addition, the coated catalyst was successfully reusable with high efficiency for up to four cycles.
Böbrek Hücrelerinin Elde Edilmesinde Üç Farklı Primer Kültür Yönteminin Karşılaştırılması
Authors: PEHLİVAN Melek , VATANSEVER Seda , ÇERÇİ Burcu , AKOĞULLARI Damla , İLBEY Yusuf Özlem , PİRİM İbrahim 
Published: September 2021

Giriş: Böbrek hücrelerinin elde edilmesinde kullanılan primer kültür yöntemi, böbrek hastalıklarının hücre düzeyinde değerlendirilmesi ve hücre fonksiyonlarının incelenmesi için olanak sağlamaktadır. Bu çalışmanın amacı böbrek primer kültürü için kullanılabilecek üç farklı izolasyon yönteminin hücre sağkalımı ve protol etkinliği açısından birbirleriyle karşılaştırılmasıdır.
Gereç ve Yöntemler: Nefrektomi ile çıkarılan böbrek dokusu steril şartlarda mekanik, tripsin ve kollagenaz yöntemi ile ayrımlanarak podosit vasatı içerisinde kültüre edildi. Kültüre edilen hücrelerin podosin, vimentin, E-kaderin, TGF-β1, CD133, ZO-1 ve Nefrin dağılımlarının analizi immünositokimyasal yöntem ile yapıldı.
Bulgular: Kollajenaz enzimatik yöntemi sonrasında hücrelerin kültürün 7. gününden itibaren, mekanik yöntemde ise 13. günden itibaren epiteloid karakter aldıkları gözlenirken, tripsin enzimatik yönteminde 13. günde kültürde artan fuziform yapıdaki hücreler gözlendi. Her üç yöntem ile böbrek dokusundan elde edilen podosit hücrelerin immunositokimyasal analizi sonrasında, elde edilen hücrelerde vimentin, E-kaderin, TGF-β, CD133, ZO-1 immunoreaktiviteleri farklılık gösterir iken, podosin ve nefrin immunoreaktivitelerinin kollajenaz enzimatik yöntemi ile elde edilen hücrelerde kuvvetli olduğu saptandı.
Tartışma: Bu çalışmada, farklı proteinlerin immunositokimyasal boyamaları ile kontrol edilen böbrek hücreleri için üç farklı primer kültür teknikleri karşılaştırıldığında, kollajenaz ile muamele edilen böbrek dokusundan daha yüksek verimle hücre saflaştırılabildiği gözlendi. Podosit hücrelerinin kültüre edilmesinde hücre sağkalım verimi ve protokol etkinliği açısından kollajenaz yönteminin en uygun yöntem olduğu gösterildi.
Application of gold nanomaterials for ionizing radiation detection
Authors: Shiratori Daiki , Nakauchi Daisuke , Kato Takumi , Kawaguchi Noriaki , Yanagida Takayuki 
Published: September 2021

Abstract
Au nanomaterials are known to change their properties significantly depending on their particle size. The prepared chloride glasses exhibited yellow emission (520 nm) upon UV rays (250 nm) irradiation, and the intensity of emission was found to decrease with X-ray dose. We concluded that this is because luminescent Au nanoclusters (AuNCs) of a few nanometers in size grow into Au nanoparticles (AuNPs) of a few tens of nanometers in size due to the photoreduction effect induced by irradiating X-ray, and the absorption (550 nm) attributed to the surface plasmon effect of AuNPs make decrease the AuNCs emissions. From the results of the changes of photoluminescence (PL) intensity concerning the irradiation X-ray dose, it was found that the PL intensity monotonically decreased 3000 mGy or more. This suggests that the Au-doped CsCl–BaCl2–ZnCl2 glass can act as an X-ray detection material in a specific dose region.
La convención Belem do pará como control de convencionalidad en materia de violencia de género
Authors: Salguero Ventura Angela Elizabeth 
Published: September 2021

En el presente ensayo, se realiza con el objetivo de hacer un análisis y fortalecer los conocimientos sobre el tipo penal de la violencia contra la mujer en Guatemala y como la Convención Belem Do Pará, debe ser el punto de partida del Estado para adecuar su normativa interna a las exigencias de los instrumentos internacionales, en especial aquellas que van dirigido a la protección de grupos vulnerables, tal como lo es las mujeres víctimas de violencia; se aborda por qué los órganos jurisdiccionales encargados de conocer los procesos de los casos de mujeres víctimas de violencia en base a la justicia especializada, deben ejercer dicha función de conformidad con el control de convencionalidad que le impone la Convención Belem Do Pará, pues esta obliga a los Estados Partes a condenar todas las formas de violencia contra la mujer y convenir en adoptar, por todos los medios apropiados y sin dilaciones, políticas orientadas a prevenir, sancionar y erradicar dicha violencia al ser observada y aplicada en los referidos procesos.
A través de la metodología de investigación, se estableció como se estructura, observa y aplica la convención Belem Dó Pará, y lograr entender y fortalecer los conocimientos de como El Estado cumple con las exigencias de los instrumentos internacionales. Como resultado del análisis respectivo de la Convención Belem Do Pará se establece que el Estado al haber ratificado la referida convención y aplicar la misma en los procesos de los casos de mujeres víctimas de violencia, cumple con las exigencias de los instrumentos internacionales en especial en cuanto al sector vulnerable de las mujeres y ayuda a erradicar la violencia contra la mujer.
Case Report: Nivolumab-Induced Autoimmune Pancreatitis
Authors: Goyal Preeya , Moyers Justin T. , Elgohary Bassem G. , Hammami Muhammad B. 
Published: September 2021

ABSTRACT
Nivolumab is an anti-programmed cell death protein 1 monoclonal antibody. While an effective treatment for a variety of tumors, immune checkpoint inhibitors (ICI) can cause immune-related adverse events such as ICI-pancreatic injury (ICI-PI). Here we present a case of a 60-year-old man with metastatic acral melanoma treated with nivolumab and ipilimumab who developed ICI-PI. Changes in positron emission tomography images preceded symptom onset. However, this case is unique in that the patient presented with cholestatic liver disease. Magnetic resonance cholangiopancreatography showed a dilated extrahepatic bile duct that resolved with steroid therapy, similar to the clinical course of autoimmune pancreatitis. ICI-PI has variable presentations including obstructive jaundice with a clinical course mimicking autoimmune pancreatitis and prompt awareness and treatment of ICI-PI is clinically significant given increasing use of ICIs.
DETERMINATION OF THE COEFFICIENT OF THE DYNAMIC SHAPE OF DUST PARTICLES RELEASED IN THE AREA OF GRINDING MACHINES
Authors: Бурьянов Иван Александрович , Логачев Иван Николаевич , Логачев Константин Иванович , Гольцов Александр Борисович 
Published: September 2021

При проведении работ по заточке твердосплавных инструментов абразивными кругами на универсальных заточных станках образуется значительное количество пылевых частиц. Часть пылевых частиц, в зависимости от размеров, находится во взвешенном состоянии. Длительное воздействие пылевых аэрозолей на организм рабочих может привезти к развитию большого количества профессиональных заболеваний дыхательных путей. Установлено, что на характер движения пылевых частиц в рабочей зоне и скорость их осаждения влияет такой параметр, как форма пылевой частицы. Материал для исследования и расчета был собран на предприятии ООО «Русский инструмент», которое расположено в пгт. Северный, Белгородского района. Отбор проб производился в разных зонах заточного участка. На основе имеющихся проб пылевых частиц, на базе лаборатории БГТУ им. В. Г. Шухова, были получены результаты электронной микроскопии. Целью данной работы является определение коэффициента формы пылевых частиц, с использованием существующих методик определения данного коэффициента. Полученные результаты позволяют дополнить исходные данные для разработки математической модели процессов течения пылевых частиц вблизи местного отсоса и последующего компьютерного моделирования течений пылевых аэрозолей в кожухе-пылеуловителе.
When working on sharpening carbide tools with abrasive wheels on universal grinding machines, a significant amount of dust particles is formed. A certain part of the dust particles, depending on the size, is suspended. Prolonged exposure to dust aerosols on the body of machine turners can lead to the development of a large number of occupational diseases of the respiratory tract. It is established that in the working area, the nature of the movement of dust particles, as well as the rate of their deposition, is affected by such a parameter as the shape of the dust particle. The material for the study, calculation and subsequent computer simulation of the dust aerosol flows in the dust collector casing was collected at the OOO Russian Tool, which is located in the village Severny, Belgorod district. The samples were taken in different zones of the grinding area. Based on the available samples of dust particles, the results of electron microscopy were obtained at the laboratory of BSTU named after V. G. Shukhov. The purpose of this work is to describe the results obtained and determine the shape coefficient of dust particles, using existing methods for determining this coefficient. The material of the work allows us to supplement the initial data for the development of a mathematical model of the processes of the flow of dust particles near the local suction.
DANDO BANDEIRA: RELATOS PARA COMUNIDADES IMAGINADAS / Dando bandeira: stories for imagined communities
Authors: Riscado Caio 
Published: September 2021

O artigo tem como objeto a análise da produção de bandeiras confeccionadas por artistas brasileiros. A partir da ideia de que bandeiras são objetos performativos e propositivos, que impulsionam a formalização de novos relatos e comunidades fora das lógicas de representatividade e pertencimento das macropolíticas, as obras Bandeyra Nacional (2015), de Frederico Costa, Amarelo, sei lá... desespero (2019), de Ítala Isis, e América é Marica (2019), de Francisco Mallmann, são utilizadas para a reflexão sobre as noções de inespecificidade na arte, desidentificação e grupalidade.Palavras-chave: Brasil; Bandeira; Representatividade; Pertencimento; Inespecificidade. AbstractThis article has as its object of analysis a set of flags made by Brazilian artists. Starting from the idea that flags are performative and propositive objects able to propel the formalization of new stories and communities outside the logics of representativity and belonging of macropolitics, the pieces Bandeyra Nacional (2015), by Frederico Costa, Amarelo, sei lá... desespero (2019), by Ítala Isis, and América é Marica (2019), by Francisco Mallmann, are used to reflect about the notions of unspecificity in art, disidentification and groupality.Keywords: Brazil; Flag; Representativity; Belonging; Unspecificity.