bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lack of Renoprotective Effects of Dopamine and Furosemide during Cardiac Surgery
Authors: LASSNIGG ANDREA , DONNER EVA , GRUBHOFER GEORG , PRESTERL ELISABETH , DRUML WILFRED , HIESMAYR MICHAEL 
Published: May 2021

Abstract.
Because development of acute renal failure is one of the most potent predictors of outcome in cardiac surgery patients, the prevention of renal dysfunction is of utmost importance in perioperative care. In a double-blind randomized controlled trial, the effectiveness of dopamine or furosemide in prevention of renal impairment after cardiac surgery was evaluated. A total of 126 patients with preoperatively normal renal function undergoing elective cardiac surgery received a continuous infusion of either “renal-dose” dopamine (2 μg/kg per min) (group D), furosemide (0.5 μg/kg per min) (group F), or isotonic sodium chloride as placebo (group P), starting at the beginning of surgery and continuing for 48 h or until discharge from the intensive care unit, whichever came first. Renal function parameters and the maximal increase of serum creatinine above baseline value within 48 h (▵Creamax) were determined. The increase in plasma creatinine was twice as high in group F as in groups D and P (P < 0.01). Acute renal injury (defined as ▵Creamax >0.5 mg/dl) occurred more frequently in group F (six of 41 patients) than in group D (one of 42) and group P (zero of 40) (P < 0.01). (The difference between group D and group P was not significant.) Creatinine clearance was lower in group F (P < 0.05). Two patients in group F required renal replacement therapy. The mean volume of infused fluids, blood urea nitrogen, serum sodium, serum potassium, and osmolar- and free-water clearance was similar in all groups. It was shown that continuous infusion of dopamine for renal protection was ineffective and was not superior to placebo in preventing postoperative dysfunction after cardiac surgery. In contrast, continuous infusion of furosemide was associated with the highest rate of renal impairment. Thus, renal-dose dopamine is ineffective and furosemide is even detrimental in the protection of renal dysfunction after cardiac surgery.
Bound in bronze – a Roman bronze statuette of a barbarian prisoner
Authors: Juhász Lajos , Kiss József Géza 
Published: May 2021

The small statuette of a bound barbarian from a Hungarian private collection is an interesting addition to the small group of these similar, although unusually harsh Roman representations of their foes. Although without a known findspot it further strengthens the previous suppositions that these were made and used for an unknown purpose at the limes, their greatest concentration being in Carnuntum.
The fibula production of Brigetio: clay moulds
Authors: Sáró Csilla 
Published: May 2021

Fibula production can be proven in the case of several Pannonian bronze workshops and among these, Brigetio as well. Similar fibula variations from a close territory can refer to the production in a certain area but the archaeological finds which belong to the manufacturing process are more trustworthy evidences. Regarding the fibulae produced in Brigetio, I. Kovrig, E. Patek, É. B. Bónis, K. Szabó, M. Merczi and N. Sey have already published some more or less detailed parts of their research. During a research project, the author reinvestigated several archaeological finds which can be related to the fibula production of Brigetio. The main aim of this paper is the definition of the fibula variants and the examination of their regional distribution. Moreover, the dating of the locally manufactured fibula variants can be helpful to define the production period of the workshops.
The results of a non-destructive site exploration and a rescue excavation at the site of Pusztaszabolcs-Dohányos völgy északi part
Authors: Váczi Gábor , Rupnik László , Czajlik Zoltán , Mesterházy Gábor , Bittner Bettina , Fülöp Kristóf , Lönhardt Denisa M. , Szabó Nóra 
Published: May 2021

It is only possible in rare cases to compare aerial photographs, fieldwork data, surveys of two types of magnetometer measurements, and metal detector surveys of a site with the results of a previous rescue excavation. The cooperation of the Castle Headquaters Integrated Developement Centre, the Szent István Király Museum of Székesfehérvár, and the Institute of Archaeological Sciences at the Eötvös Loránd University made the discovery of the multi-period site on the outskirts of Pusztaszabolcs possible.
Excavations in Brigetio in 2020
Authors: Bartus Dávid , Borhy László , Számadó Emese , Juhász Lajos , Simon Bence , Barna Ferenc , Benes Anita , Joháczi Szilvia , Olasz Rita , Szabó Melinda 
Published: May 2021

In 2020, excavations were carried out simultaneously at several locations both in the territory of the legionary fortress and the military town of Brigetio. As a result, new information was gained regarding the structure of the legionary fortress and a number of late Roman period graves were also identified. The most significant result of the campaign was the excavation of an almost intact cellar in the western zone of the canabae.
Middle Iron Age Cemetery from Alsónyék, Hungary
Authors: Soós Bence 
Published: May 2021

In 2008 a section of a Middle Iron Age cemetery was unearthed at Alsónyék (Tolna County, Hungary). The 16 graves can be dated broadly to the 5th and maybe the early 4th century BC. The significance of this discovery lies in the diversity of burial customs and grave goods as well as in the fact that sites from this period are relatively rare in Transdanubia. In addition, already these 16 graves make the cemetery the second largest Middle Iron Age graveyard in the region between the Kapos and Sava Rivers.
Comparing the efficacy of laparoscopic and open radical prostatectomy: analysis of treatment outcomes in patients with prostate cancer treated in three federal centers
Authors: Nyushko K. M. , Perepukhov V. P. , Kozlova P. S. , Chaykov V. S. , Shchukina E. O. , Dementyev I. O. , Krasheninnikov A. A. , Shevchuk I. M. , Alekseev B. Ya. , Kaprin A. D. , Ivanov S. A. , Karyakin O. B. 
Published: May 2021

Background. Prostate cancer is currently one of the most challenging problems in urological oncology due to its constantly increasing incidence and mortality in Russia. Surgery remains one of the most radical treatment options for patients with localized and locally advanced prostate cancer of any risk. Multiple studies have compared long-term and functional outcomes of surgeries performed using different surgical approaches. All studies have demonstrated similar long-term and functional outcomes of open, laparoscopic, and robot-assisted surgeries. Objective: to review the existing literature on this problem and analyze outcomes of surgical treatment in patients who had undergone open or laparoscopic prostatectomy in one of three federal centers of the National Medical Research Radiology Center.Materials and methods. This retrospective study included 2,772 patients with localized and locally advanced prostate cancer who had undergone surgery in one of the three federal centers.Results. We evaluated short-term and long-term outcomes of laparoscopic and open radical retropubic prostatectomy (RRP) performed at three federal centers of the National Medical Research Radiology Center. We found that laparoscopic RRP was associated with a longer surgery, lower blood loss, and fewer lymph nodes removed compared to open RRP. Long-term oncological and functional outcomes (prostate-specific antigen relapse-free survival, time to urination recovery) did not significantly differ between patients who had laparoscopic or open RRP.Conclusion. Both open and laparoscopic RRP are equally effective surgical methods for patients with localized and locally advanced prostate cancer.
Prognostic factors for restoring orgasmic function in patients after radical prostatectomy
Authors: Veliev R. A. , Veliev E. I. , Sokolov E. A. 
Published: May 2021

Background. Radical prostatectomy (RP) remains the gold standard in prostate cancer treatment. RP often has side effects that negatively affects quality of life. Influence on sexual life, in particular, orgasmic function (OF) of patients is one of the most actual issues that require additional research.Objective. Analysis of OF after RP as well as OF's pathologies are presented in our study.Materials and methods. The study includes 146 patients with safe sexual life on preoperative period, who underwent RP for prostate cancer in S.P. Botkin City Clinical Hospital. 79.5 % had robot-assisted laparoscopic prostatectomy and 20.5 % — retropubic RP. Mean age of patients was 61.1 ± 6.5 years. Erectile function was assessed by the International Index of Erectile Function (IIEF), the sum median was 25 points. Observation period was 12 months.Results. OF recovered in 65.7 % of patients in one year after RP versus 30.1 % in erectile function recovery. Climacturia was detected in 21.9 % patients, painful orgasm in 13 % patients.Conclusion. OF recovered in most patients till the end of the first year of observation. Younger age, safe pre- and postoperative erectile function, nerve-sparing surgery have positively affected OF recovery. Further researches needed to find statistically more relevant OF recovery predictors after RP, prevention of its pathologies.
The Role of Site Conditions on the Structural Damage in the City of Valdivia during the 22 May 1960 Mw 9.5 Megathrust Chile Earthquake
Authors: Pastén César , Campos Felipe , Ochoa-Cornejo Felipe , Ruiz Sergio , Valdebenito Galo , Alvarado David , Leyton Felipe , Moffat Ricardo 
Published: May 2021

Abstract
The 22 May 1960 Mw 9.5 Valdivia megathrust earthquake, with a rupture length close to 1000 km in the central–south Chile, is the largest recorded earthquake in the modern times. The city of Valdivia is located about 300 km south of the northern boundary of the rupture in front of one of the largest asperities of the earthquake. In this article, we analyze the geology of the city and results from geophysical exploration methods that could explain the observed pattern of structural earthquake-induced damage. Surface waves methods results indicate that the soils in Valdivia have shear-wave velocity in the upper 30 m VS30 ranging from 150 to 300  m/s, whereas horizontal-to-vertical spectral ratios (HVSRs) calculated from ambient seismic noise show predominant vibration periods between 0.6 and 1.4 s. The housing stock in Valdivia at the time of the earthquake mainly consisted of one- and two-story wooden buildings, and fewer masonry and reinforced-concrete buildings. Our reinterpretation of the data indicates that despite the large seismic demand and the low shear-wave velocities, well-designed, well-constructed, and founded structures were barely damaged. Most of the structural damage concentrated in hybrid structural systems, poorly designed and constructed structures, and structures with deficient foundations build over uncontrolled backfills that experienced lateral movement and differential settlement. The predominant vibration periods from the HVSR do not correlate with the most damaged areas, but it seems to correlate with the depth of the soil deposit. The reduced damage of the larger structures in the city at the time of the earthquake may be partially explained because their vibration periods did not resonate with the predominant vibration period of the soil, in addition to their large structural redundancy.
Earthquake Depths, Focal Mechanisms, and Stress in the Lower St. Lawrence Seismic Zone
Authors: Plourde Alexandre P. , Nedimović Mladen R. 
Published: May 2021

AbstractWe examine earthquake hypocenters, focal mechanisms, and the state of tectonic stress in the Lower St. Lawrence Seismic Zone (LSZ), a paleorift zone in eastern Canada. The largest earthquake recorded in the region is the 1999 Côte–Nord MN 5.1, which was followed by ∼80 aftershocks of MN&gt;1. It is not known if the region is capable of producing hazardous Mw&gt;6 earthquakes, similar to the Charlevoix Seismic Zone ∼250  km upriver. Focusing on 2015–2020, we apply a machine-learning-based phase picker to detect 72 earthquakes in addition to the 150 catalog earthquakes in the same region over this time span. We produce an updated 1D, gradient velocity model via a Monte Carlo search using a uniform VP/VS=1.77, which we computed with the Wadati method. We refine hypocenter estimates using the triple-difference method, with sP depth phases as additional constraints on earthquake depth. We estimate focal mechanisms for &gt;100 earthquakes with automatically picked P-wave first motions and absolute value P-SV-SH amplitude ratios, and we use the focal mechanisms to invert for the state of tectonic stress. Grid searches and Bayesian analysis allow for robust uncertainty estimates of focal mechanisms, which in turn allow for uncertainty estimates of the stress tensor. The recovered west-northwest–east-southeast σ1 is consistent with previous estimates and with a stress tensor controlled by glacial isostatic adjustment, although a contrast between deep and shallow focal mechanisms suggests that these stresses may be concentrated in the lower crust. Epicenter lineations up to ∼40  km long may be indicative of sizable faults in the LSZ capable of generating Mw&gt;6 earthquakes, but hypocenter and focal mechanism uncertainties are too high to say so definitively, thus pointing to a need for denser station coverage, including ocean-bottom seismometers.
THE ESTIMATION OF THE RESULTS OF THE PATIENTS WITH THE TEMPOROMANDIBULAR JOINT DYSFUNCTION DEPENDING ON THE HABITUAL PHYSICAL ACTIVITY TYPE
Authors: Mokshantsev Denis , Mamchits Elena , Bragin Aleksandr , Retrunyak Valery , Zubareva Anna 
Published: May 2021

Subject. The study of the results of the examination of the patients with the temporomandibular joint dysfunction depending on the habitual physical activity type.
The aim of the study is to estimate the results of the examination of the patients with the temporomandibular joint dysfunction depending on the habitual physical activity type.
Methodology. 105 patients (18 male patients and 87 female patients) aged 20-35 with the occlusive temporomandibular joint dysfunction (K07.6 Diseases of temporomandibular joint) living in Tyumen and in Tyumen region were examined. The study was carried out at “the Regional stomatological polyclinic” in Tyumen.
Results. The study of the peculiarities of temporomandibular joint dysfunction depending on the habitual physical activity type was carried out. The clinical results of the dynamic observation and complex functional study in 105 patients aged 20-35 having occlusive temporomandibular joint dysfunction were given.
Conclusion. The results showed that there was a direct connection between the changes in dentomandibular system and the physical activity level in 105 patients aged 20-35 with occlusive temporomandibular joint dysfunction living in Tyumen and Tyumen region.
In the studied subjects, with a a low level of habitual motor activi 8.43% more defects in the dentition were found in comparison with a high level of habitual motor activity, and by 6.02% more than in comparison with an average level of habitual motor activity, the pathological abrasion of the teeth was almost 2 times higher compared with a high level of habitual motor activity.
An additional examination method based on computed tomography showed a violation of the articular relationship in 67.3% of cases, signs of TMJ hypermobility one and two-sided in 28.2%, changes in the position of the condyles in the joint in 33.33% of cases, in the group with a low level of habitual motor activity.
SYSTEMIC AND DENTAL PATHOLOGY OF A PATIENT WITH RHEUMATOID ARTHRITIS ON THE BACKGROUND OF METOTREXATE THERAPY (CLINICAL CASE)
Authors: Anisimova Irina , Simonyan Laura , Balchytis Vladimir 
Published: May 2021

Background. One of the urgent problems of modern medicine is the formation and development of an interprofessional approach to the complex therapy of patients with combined pathology. An interdisciplinary approach to the examination and treatment of patients with concomitant diseases is due to the interconnection of the oral mucosa with systemic diseases. Literature data indicate the pathogenetic commonality of systemic connective tissue diseases, including rheumatoid arthritis with periodontitis and oral mucosa diseases, which is based on a diffuse inflammatory process.
Objectives ― study of a clinical case of combined lesion of the oral mucosa of a patient with rheumatoid arthritis during treatment with methotrexate.
Methods. We examined patient R. — an elderly man of 72-year-old with ulcerative and necrotic lesions of the oral mucosa, simultaneously suffering from rheumatoid arthritis and receiving methotrexate as maintenance therapy. The patient was sent to the Department of Therapeutic Dentistry of Omsk State Medical University, to the clinical base of dental clinic № 1 in Omsk in order to clarify the diagnosis and prescribe complex treatment.
Results. Patient R. revealed a combined ulcerative-necrotic lesion of the oral mucosa and gums with rheumatoid arthritis. Joint general and local medical treatment by a dentist of lesions of the oral mucosa, gums, examination, observation in dynamics and the advice of a physician-therapist in terms of prescribing maintenance therapy for rheumatoid arthritis by reducing the dose of the drug (methotrexate) gave a joint positive effect in a comprehensive interdisciplinary approach to the treatment of a patient with comorbid pathology.
Conclusions. Our research has shown that it is necessary to increase activity in the development of an interdisciplinary collaboration between dentists and internists. The continuity and friendship of doctors of different specialties make it possible to get a positive result in the treatment and improve the quality of life of patients.
CHANGES IN PHYSICO-CHEMICAL AND BIOCHEMICAL INDICATORS OF ORAL FLUID DURING LOCAL TREATMENT OF GINGIVITIS IN PREGNANT WOMEN WITH GESTOSIS
Authors: Chuykin Sergey , Kudashkina Natalia , AKATYEVA Galina , Chuykin Oleg , Makusheva Natal'ya , Egorova Elena , Maganova Zarema , Kuchuk Kristina 
Published: May 2021

Introduction. Gestosis (late toxicosis of pregnant women) — pathological conditions of the second half of pregnancy, characterized by a triad of main symptoms: edema (hidden and visible), proteinuria, hypertension. In the third trimester, during physiological pregnancy of women and, especially when it is complicated by gestosis, there is a decrease in salivation, an increase in the viscosity and acidity of the oral fluid, which significantly increases the severity of the course of inflammatory periodontal diseases. We have developed a method for local treatment and prevention of gingivitis in women with pregnancy complicated by preeclampsia using a chewing phyto-substrate.
Purpose: to assess changes in the physicochemical and biochemical parameters of the oral fluid during the local treatment of gingivitis using a chewing phyto-substrate in pregnant women with gestosis.
Materials and methods: the examination of pregnant women was carried out in cooperation with obstetricians-gynecologists at the clinical base of the Department of Obstetrics and Gynecology No. 2 at the City Clinical Hospital No. 8, Ufa. Physicochemical (salivation rate, kinematic viscosity, pH) and biochemical parameters (calcium, magnesium, phosphorus, protein) of the oral fluid were determined before and after complex treatment of gingivitis with the inclusion of a chewing phyto-substrate in pregnant women with gestosis.
Conclusion: in the third trimester during physiological pregnancy and, especially when it is complicated by gestosis, there is a decrease in salivation, an increase in the viscosity and acidity of the oral fluid. The use of chewing phytosubstrate plates in complex treatment, containing 0.1 g of dry extract of the collection (oak bark, licorice alder, birch buds, chamomile flowers, thyme herb) and 1.0 g of beeswax, increases the rate of salivation by 1.5 times, reduces the viscosity of the oral fluid by 1.3 times and its acidity, which indicates the effectiveness of the proposed method of local treatment of gingivitis in pregnant women with preeclampsia.
A indevida aplicação do enunciado de Súmula n. 281 do Tribunal de Contas da União e a proibição da participação de cooperativas de trabalho brasileiras em procedimentos licitatórios
Authors: Ferraz Teixeira Marianna 
Published: May 2021

O presente trabalho busca analisar o enunciado de Súmula n. 281 do Tribunal de Contas da União, aprovada em 11 de julho de 2012, que veda a participação de cooperativas de trabalho em licitações quando o serviço a ser prestado exija a necessidade de subordinação, habitualidade e pessoalidade. Apesar das previsões da Lei de Licitações e da Lei de Cooperativas de Trabalho disporem que dito impedimento é proibido, muitos procedimentos licitatórios, em razão da súmula, excluem esse tipo societário da participação, o que faz com que princípios como o da legalidade e da igualdade sejam violados, assim como afronta o preceito constitucional de fomento ao cooperativismo como meio de desenvolvimento da atividade econômica e da redução do desemprego. Essa conduta, além de prejudicar o mercado de trabalho, também gera prejuízo à Administração Pública, que será tolhida do seu direito e dever de selecionar a proposta mais vantajosa, haja vista que não terá acesso, de fato, a todas as propostas cabíveis.
Recibido: 26 octubre 2020Aceptado: 10 diciembre 2020
The artistic intuition and its impact in developing the leadership potentials of the academic women in the specializations of art and design
Authors: Al Sheikh Hanan Muneer 
Published: May 2021

The artwork towards which academic women are going in the specializations of art and design is considered as a comprehensive philosophical intellectual system; as the academic woman while understanding art is unifying psychological elements with the philosophical, intuitive, and spiritual elements. This research tackles the analysis of the concept of artistic intuition as a compositional activity that reflects to all practical life fields but under specific humanitarian conditions that distinguish leading women particularly in the specializations of art and design. Such analysis leads to being aware of all dilemmas related to the artistic intuition and not only that related to artwork; but also, the intuition that becomes expressive in the philosophical concept. It is not separate from the state of being rather than integrating in the form of a coordinated theory with the purpose of understanding human in the different varied contexts that are in harmony with his intellect, philosophy, potentials, and accumulated knowledge.
Keywords: Artistic Intuition, Art Philosophy, Leading Woman.