bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development, Reliability and Validity of Infectious Disease Specialist Nurse’s Core Competence Scale
Authors: Wu Chao , Yan Jiaran , Wu Jing , Wu Ping , Cheng Feixia , Du Lina , Du Yanling , Shang Lei , Lang Hong-juan 
Published: October 2021

Abstract
Aim: This study aimsto develop an instrument to measure infectious disease specialist nurses’ core competence and examining the scale’s validity and reliability.Background: With the increase of infectious diseases, more and more attention has been paid to infectious disease nursing care. The core competence of the infectious disease specialist nurses is directly related to the quality of nursing work. In previous researches, infectious disease specialist nurses’ core competence was measured bythe tools developed for general nursesinstead of specialized tools, which made it difficult to clarify the core competence of nurses in infectious diseases department.Methods: Preliminary items were developed through literature review, theoretical research, qualitative interview and Delphi method. The confirmed 47 items were applied in the two rounds of data collection. Evaluation data on 516 infectious disease specialist nurses’ core competence in the first round were utilized to preliminarily evaluate and explore the scale’s constrution, whileevaluation data on 497 infectious disease specialist nurses’ core competence in the second round were utilized to doreliability analysis and validity analysis. In this study, factor analysis, Cronbach's a, Pearson correlation coefficients were all adopted.Results: The final scaleis composed of 34 items and 5 factors, and adoptedthe 5-point scoring method. The factors areProfessional Development Abilities, Infection Prevention and Control Abilities, Nursing Abilities for Infectious Diseases, Professionalism and Humanistic Accomplishment, and Responsiveness to Emergency Infectious Diseases.The explanatory variance of the five factors was 75.569%. The reliability and validity of the scale is well validated.The internal consistency, split-half reliability and test-retest reliability were 0.806, 0.966 and 0.831 respectively.The scale has good structural validity and content validity. The content validity was 0.869. Discrimination analysisshowed that there were significant differences in the scores of core competence and its five dimensions among infectious disease specialist nurses of different ages, working years in infectious diseases, titles, educational background, marital status and wages (all P< 0.05).Conclusions:The proposed scale takes on high reliability and validity,and is suitable for assessing the infectious disease specialist nurses’ core competence.Relevance to clinical practice: This scale provides a reference for clinical assessment of infectious disease nursing.
Publication Trends Related to Social Capital and Governance: Bibliometric Analysis
Authors: Baharuddin Tawakkal , Sairin Sjafri , Qodir Zuly , Jubba Hasse 
Published: October 2021

Abstract
This article analyzes the trend of publications related to social capital with governance. This study used bibliometric analysis with the data source coming from the research database, called Scopus. The analytical tool used was Vosviewer analysis software. Vosviewer assisted the process of determining the calculated weights and selection of relevant published documents. The findings of this study indicated that the concept of social capital was to analyze proper governance systems by assessing aspects of networking, collaboration, and trust in the relationship between the private sector, the community, and the government. Several new topics in research publications have been experiencing a reasonably good trend that is rarely studied, including conflict resolution and co-management. These two themes are relatively new, especially in social capital. In addition to these themes, general themes in research publications were found, including coastal protection, environmental, climate change, and network governance. These themes are rarely published but still considered important in influencing other research publication trends to date. The contribution of this research is deemed critical to the development of research on social capital with governance systems. A bibliometric analysis approach in this study can influence subsequent studies in compiling and shaping the contribution position.
Oxidation Modification of Fuorinated Graphite and Its Reaction Mechanism
Authors: Li Hao , Bi Song , Yuan Xiaojing , Liu Zhaohui , Song Yongzhi , Wang Jinjin , Hou Genliang 
Published: October 2021

Abstract
In this paper, Hummers method was used to oxidize ﬂuorinated graphite in order to study the modification mechanism. The chemical composition and microstructure of the products before and after the reaction were characterized and analyzed. Oxidized fluorinated graphite (OFG) obtained by oxidation has a thin layered structure and different oxygen content. The main mechanism of KMnO4 modification is that MnO3+ with Lewis acid property can catalyze the activation of the fluorocarbon bond, which breaks to form F ion. At the same time, the unsaturated carbon bond is oxidized, resulting in the increase of carbon oxygen bond content and the generation of some OFG nano fragments. With the increase in KMnO4 dosage, the fluorocarbon bond will be gradually catalyzed to react according to its activity while the unsaturated carbon bond is oxidized, finally there are still some isolated fluorocarbon bonds with weak activity.
Breast cancer segmentation and classification in ultrasound images using convolutional neural network
Authors: Dizaj Shima Baniadam , Valizadeh Pourya 
Published: October 2021

Abstract
Breast most cancers is one of the main reasons of mortality in ladies throughout the world. Early detection contributes to a discount withinside the quantity of untimely fatalities. Using ultrasound (US) pics, we gift deep studying (DL) strategies for breast most cancers segmentation and category into 3 classes: regular, benign, and malignant. The versions in most cancers length and traits are the mission of segmentation and category tasks. The proposed technique became evolved and evaluated the use of US pics amassed from 780 breast cancers. This has a look at tested using deep studying to scientific pics of breast most cancers acquired with the aid of using ultrasound scan. For evaluation, we used intersection over union (IoU), accuracy. When evaluated with IoU the nice proposed technique yielded 100%curacy on regular breast segmentation, 79.27% on benign, and 93.73% on malignant most cancers. Also, the accuracy of category three classes is 87.86%. Our have a look at indicates the usefulness of deep studying techniques for breast most cancers segmentation and category. You can locate the preskilled weights and elements of our Implementation and the prediction of our technique may be located at https://github.com/shb8086/Cancer.
Relationship Between Physical Activity Level and Characteristics of Patients with Cancer
Authors: Corrêa Raphaela Espanha , Tolocka Rute Estanislava 
Published: October 2021

Evidences have shown that Physical Activity (PA) can decrease side effects, such as fatigue and pain, as well as promote increase of muscular endurance, oxygen consumption and quality of life) of patients with different phases of cancer treatments. However, studies have demonstrated that patients with cancer diagnosis may show insufficient levels of PA. Therefore, it is necessary to check the profile of such patients. Thus, the aim of this study was to analyze PA level and the sociodemographic and clinical profile of patients with cancer. It is a field study that included 247 patients of both sex, above 18 years old any type of cancer. The International Physical Activity Questionnaire-IPAQ-Bref was used to measure PA and the clinical profile was assessed using a questionnaire. The breast cancer was most common type (32.4%), the mean age was 60.08 ± 13.12 and patients in general have inadequate levels of PA, independent of treatment phase. It was found negative association between age and time of PA (rho=-0.145, p<0.05), years of diagnosis were associated with the level of PA: less than one year of diagnosis can be a significant predictor of low physical activity level (OR= 28.457; 95% CI 1.706 – 474.589; p= 0.020) and for moderate physical activity level (OR= 29.578; 95% CI 1.409 – 620.746; p= 0.029), Implementation of public policies to spread information and to offer PA programs to patients with cancer are needed, especially in the beginning of the treatment.
ANÁLISE DAS INFORMAÇÕES SOBRE O MEDICAMENTO METILFENIDATO (RITALINA®) DIVULGADAS EM VÍDEOS DO YOUTUBE
Authors: Valente Juliana Givisiez , Abreu Paula Alvarez 
Published: October 2021

Este trabalho tem como objetivo analisar a qualidade, o tipo de informação e o impacto dos vídeos do YouTube sobre o medicamento cloridrato de metilfenidato (Ritalina®) que apesar de indicado para transtorno de déficit de atenção e hiperatividade (TDAH), vem sendo usado de forma irracional visando benefícios nos estudos. Foram obtidos os 60 vídeos mais relevantes sobre o tema usando a palavra-chave Ritalina, sendo excluídos 2 vídeos por não discutirem questões pertinentes ao uso do medicamento. Os 58 vídeos obtidos foram analisados e as informações divulgadas foram comparadas com aquelas constantes na bula do medicamento e na base de dados Micromedex®, bem como avaliado o tipo de informação divulgada e a presença de profissional de saúde ou de usuários do medicamento nos vídeos. Em 33 vídeos (57%) houve a participação de profissionais de saúde que divulgaram informações corretas e desestimularam o consumo indevido da Ritalina. Já 9 vídeos (15%) também apresentaram informações corretas, porém não foram divulgadas por profissionais de saúde. Nos vídeos com relato de usuários, em 12 (21%), houve relatos de uso para melhorar o desempenho intelectual, atribuindo ao medicamento propriedades não comprovadas cientificamente. Esses números mostraram que a maior parte dos vídeos, totalizando 46 (79%) parecem não comprometer o uso correto do medicamento, entretanto 12 vídeos (21%) incentivaram o uso da Ritalina como estimulante para estudo e, por isso, representam um risco ao uso racional de medicamentos.
AVALIAÇÃO DOS MICRORGANISMOS VIÁVEIS POTENCIALMENTE PATOGÊNICOS EM BIOAEROSSÓIS EM UMA UNIDADE DE TERAPIA INTENSIVA
Authors: Cavalheiro Tharinne Oliveira Silva , Kozusny-Andreani Dora Inés 
Published: October 2021

Bioaerossóis são partículas transportadas pelo ar que se originam de micro-organismos vivos, como bactérias, fungos e vírus e, podem permanecer suspensos e viáveis ​​na corrente de ar por longos períodos de tempo. Seus componentes têm efeitos negativos, especialmente na saúde de pessoas imunocomprometidas. Objetivou-se avaliar a presença de microrganismos viáveis potencialmente patogênicos em bioaerossóis de uma Unidade de Terapia Intensiva de um hospital do noroeste paulista.. Para a pesquisa foram colhidas amostras do ar de locais definidos. Todas as amostras foram cultivadas em Placas de Petri contendo meios seletivos e não seletivos para bactérias e fungos, incubadas à temperatura de 37 ºC por 24-48h para cultivos bacterianos e de 4 a 15 dias para cultivos fúngicos. Posteriormente, foi realizada a avaliação das características das colônias bem como a identificação por métodos bioquímicos convencionas. Os resultados obtidos evidenciaram a presença de leveduras das espécies Candida albicans e Candida spp e bactérias gram-positivas Staphylococcus aureus, S. epidermidis e Micrococcus spp, gram-negativas Escherichia coli e Klebsiella spp. Verificou-se pradrão de resistência a antibióticos em E. coli e Micrococcus spp, S. aureus foi sensível a maioria dos antibióticos, enquanto foi possível observar 100% de sensibilidades para S. epidermidis e Klebsiella spp.
EDUCANDO SABERES POR MEIO DO XADREZ: RELATO DE EXPERIÊNCIAS DE ENSINO
Authors: Menegotto Eduardo José , Santini Heloisa , Massashi Horiguti Augusto 
Published: October 2021

Os quatro pilares da educação para o século XXI, baseados no relatório da UNESCO, são: saber conhecer, ser, fazer e conviver. Podemos depreender que o xadrez abrange estes aspectos, contribuindo no processo educativo. Utilizado como instrumento complementar ao ensino, favorece a expansão de diversas potencialidades e o aprendizado de um modo agradável, lúdico e inclusivo. O projeto de Xadrez do Campus Caxias do Sul do IFRS, foi iniciado em 2015 e tem por objetivo proporcionar a aprendizagem e o aperfeiçoamento em Xadrez, que é um esporte, ciência, cultura e arte. A sua prática prepara os estudantes para enfrentar a vida com muito mais técnica, astúcia, respeito, caráter, tenacidade e contribuir na tomada de decisões em diferentes contextos. A equipe de execução é composta por servidores, bolsistas e a parceria com o Campus Farroupilha do IFRS. As atividades do projeto são realizadas por meio de encontros semanais com duração de até duas horas, divididos em níveis. Uma das ações voltadas aos estudantes com necessidades educativas especiais é o Xadrez Acessível. O compartilhamento de saberes em encontros, oficinas, eventos científicos, jogos escolares e torneios, reflete a indissociabilidade entre ensino, pesquisa e extensão. Como resultados, os estudos têm contribuído para o processo de construção do perfil dos egressos e colocado o ensino do IFRS em evidência, podendo-se citar como exemplos o bicampeonato dos Jogos Escolares de Caxias do Sul e as participações nos JERGS, JIFRS e JIFSul. Além disso, desde 2017 busca-se a participação da comunidade externa com a realização do Torneio de Xadrez do IFRS Campus Caxias do Sul. A importância do projeto vai além das premiações, ocorrendo no processo formativo, estimulando o desenvolvimento dos saberes, agregando valores e habilidades como resiliência, respeito e disciplina, o que contribui, de forma efetiva, para a formação dos estudantes como indivíduos e membros da sociedade.
Estimating the economic impact of large hydropower projects: a dynamic multi-regional computable general equilibrium analysis
Authors: Ni Hongzhen , Zhao Jing , Peng Xiujian , Chen Genfa 
Published: October 2021

Abstract
In response to rapidly growing energy demands, Chinese authorities plan to invest more in hydropower development. However, there are concerns about the possible effects on macroeconomy. This paper uses SinoTERM, a dynamic multi-regional computable general equilibrium model (CGE) of the Chinese economy, to analyze the economic impact of large hydropower development projects. The model features regional labor market dynamics and an electricity subdivision module with substitutability between various types of electricity generation. The results suggest that hydropower development will boost economic growth in the project region. Most sectors in the project region will benefit from the hydropower development such as other services, health, and education, while some sectors will suffer a loss in output because of the substantial increase in real wages. For the national, every 10,000 yuan investment can drive the national GDP growth of 1,000 yuan, and the cost is expected to be recovered in ten years. By the end of 2040, the real national wage will be around 0.16% higher than the baseline scenario. The project could only be justified if net environmental benefits outweigh this loss.
Real-time burst detection based on multiple features of pressure data
Authors: Zhang Xiangqiu , Long Zhihong , Yao Tian , Zhou Hua , Yu Tingchao , Zhou Yongchao 
Published: October 2021

Abstract
Pipe bursts are an essential issue for water loss in water distribution systems. This study proposes a real-time burst detection method that combines multiple data features of multiple time steps. The method sets burst thresholds in three dimensions according to different moments at a specific monitoring point, and achieves burst identification based on a classification model. First, three data features, namely, absolute pressure value, predicted deviation value obtained by pressure variation value, of historical pressure at each time step are scored based on the Western Electric Company rules. The scores represent different abnormalities. Then, the scores corresponding to the three features are used as input of the decision tree classification model. The trained model is used for detecting burst events. Results show that this method achieves 99.56% detection accuracy, indicating that it is effective for burst detection. The proposed method outperformed the single-feature-based method and provides good results in water distribution systems.
A risk assessment model of WSMC projects under emergencies
Authors: Wang Xiaosheng , Li Wei , Guo Haiying , Li Ran 
Published: October 2021

Abstract
As a novel market-based water-saving mechanism, the Water Saving Management Contract (WSMC) project faces interruption risk caused by emergencies like the coronavirus disease-2019 (COVID-19) pandemic. An interruption risk assessment model of WSMC projects is established through a quantitative evaluation of the impact of emergencies on water users based on input-output theory. First, the concept of the interruption risk index (IRI) is defined as a function of the duration of enterprise shutdown (DES). Second, the DES is divided into two parts: the duration caused by COVID-19 and that under other types of emergencies. Third, the risk tolerance threshold is given to estimate the interruption result, and its different consequences are discussed. Finally, a WSMC project in China is taken as a case study, and its interruption risks are analysed. The results show that the IRIs of this WSMC in both 2020 and 2021 are theoretically greater than the risk tolerance thresholds, and the high pandemic prevention standards and conservative pandemic estimates are the main reasons for the above results. The model established in this study provides a reference for WSMC participants to deal with emergencies and provides the theoretical support for the extension of the WSMC.
Comparison between different infiltration models to describe the infiltration of permeable brick pavement system via a laboratory-scale experiment
Authors: Song Jianying , Wang Jianlong , Wang Wenhai , Peng Liuwei , Li Hongxin , Zhang Changhe , Fang Xing 
Published: October 2021

Abstract
The permeable brick pavement system (PBPs) is one of a widely used low impact development (LID) measures to alleviate runoff volume and pollution caused by urbanization. The performance of PBPs on decreasing runoff volume is decided by its permeability, and it was general described by hydraulic conductivity based on Darcy's law. But there is large error when using hydraulic conductivity to describe the infiltration of PBPs, and which infiltration process is not following Darcy's law, so it is important to find more accurate infiltration models to describe the infiltration of PBPs. The Horton, Philip, Green-Ampt, and Kostiakov infiltration models were selected to find an optimal model to investigate infiltration performance of PBPs via a laboratory-scale experiment, and the maximum absolute error (MAE), Bias, and coefficient of determination (R2) were selected to evaluate the models' errors via fitting with experiment data. The results showed that the fitting accuracy of Kostiakov, Philip, and Green-Ampt models was significantly affected by the monitoring area and hydraulic gradients. Meanwhile, Horton model fitted well (MAE = 0.25–0.32 cm/h, Bias = 0.07–0.11 cm/h, and R2 = 0.98–0.99) with the experiment data, and the parameters of the Horton model often can be achieved by monitoring, such as the maximum infiltration rate and the stable infiltration rate. Therefore, the Horton model is an optimal model to describe the infiltration performance of PBPs, which can also be adopted to evaluate hydrological characterization of PBPs.
Metabolism is not a Major Contributor to the Toxicity of Piperaquine, a Long-acting Antimalarial Agent in Artemisinin-based Combination Therapy
Authors: Zhang Liyuan , Liu Zhaohua , Zhang Yunrui , Xie Yuewu , Xing Jie 
Published: October 2021

Background:
Hepatocellular damage has been reported for the antimalarial piperaquine (PQ) in the clinic
after cumulative doses.

Objectives:
The role of metabolism in PQ toxicity was evaluated, and the mechanism mediating PQ hepatotoxicity
was investigated.

Method:
The toxicity of PQ and its major metabolite (PQ N-oxide; M1) in mice was evaluated in terms of serum
biochemical parameters. The role of metabolism in PQ toxicity was investigated in mice pretreated with an inhibitor
of CYP450 (ABT) and/or FMO enzyme (MMI). The dose-dependent pharmacokinetics of PQ and M1 were studied
in mice. Histopathological examination was performed to reveal the mechanism mediating PQ hepatotoxicity.

Results:
Serum biochemical levels (ALT and BUN) increased significantly (P < 0.05) in mice after three-day oral
doses of PQ (> 200 mg/kg/day), indicating hepatotoxicity and nephrotoxicity of PQ at a high dose. Weaker toxicity
was observed for M1. Pretreatment with ABT and/or MMI did not increase PQ toxicity. PQ and M1 showed linear
pharmacokinetics in mice after a single oral dose, and multiple oral doses led to their cumulative exposures. Histopathological
examination showed that a high dose of PQ (> 200 mg/kg/day for three days) could induce hepatocyte
apoptosis. The mRNA levels of targets in NF-κB and p53 pathways could be up-regulated by 2-30-fold in mice by
PQ or M1.

Conclusions:
PQ metabolism led to detoxification of PQ, but there was a low possibility of altered toxicity induced
by metabolism inhibition. The hepatotoxicity of PQ and its N-oxidation metabolite was partly mediated by NF-κB
inflammatory pathway and p53 apoptosis pathway.
Raising Climate-Resilient Crops: Journey From the Conventional Breeding
to New Breeding Approaches
Authors: Gaba Yashika , Pareek Ashwani , Singla-Pareek Sneh Lata 
Published: October 2021

Background:
In order to meet the demands of the ever-increasing human population, it
has become necessary to raise climate-resilient crops. Plant breeding, which involves crossing and
selecting superior gene pools, has contributed tremendously towards achieving this goal during the
past few decades. The relatively newer methods of crop improvement based on genetic engineering
are relatively simple, and targets can be achieved in an expeditious manner. More recently emerged
genome editing technique using CRISPR has raised strong hopes among plant scientists for precise
integration of valuable traits and removal of undesirable ones.

Conclusion:
Genome editing using Site-Specific Nucleases (SSNs) is a good alternative to the
plant breeding and genetic engineering approaches as it can modify the genomes specifically and
precisely at the target site in the host genome. Another added advantage of the genome editing approach
is the simpler biosafety regulations that have been adopted by many countries for commercialization
of the products thus generated. This review provides a critical assessment of the available
methods for improving the stress tolerance in crop plants. Special emphasis has been given on
genome editing approach in light of the diversity of tools, which are being discovered on an everyday
basis and the practical applications of the same. This information will serve as a beginner’s
guide to initiate the crop improvement programs as well as giving technical insight to the expert to
plan the research strategically to tackle even multigenic traits in crop plants.