bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERENCANAAN REST AREA DENGAN KONSEP MICHI-NO EKI DI JALUR NON-TOL (Studi Kasus: Kabupaten Barru, Provinsi Sulawesi Selatan)
Authors: Lukman Muhammad Yusri , Zaki Muhammad , H Rako Ermywati 
Published: February 2021

Penelitian ini adalah dasar acuan analisis dan standar yang akan digunakan dalam pekerjaan pembangunan tempat peristirahatan pengguna jalan raya. Penelitian ini bersifat deskriptif, Penelitian dilakukan di kecamatan Soppeng Riaja desa Lawallu Kabupaten Barru Provinsi Sulawesi selatan. Pengumpulan data dilakukan melalui observasi dan wawancara. Data kendaraan yang dibutuhkan disamping volume arus lalulintas adalah jenis kendaraan dan arah pergerakannya. Metode analisis yang digunakan adalah metode hubungan sebab akibat. Suatu fenomena akan dianalisis tentang akibat yang terjadi dari suatu perlakuan. Hasil kajian yang memberi dampak positif akan dikembangkan sementara efek kajian yang bernilai negatif akan ditelusuri secara mendalam untuk mendapatkan hasil keputusan optimal. Metode dan standar ini meliputi dasar hukum perbandingan dan ketentuan dasar pergerakan kendaraan. Standar yang dimaksudkan dalam pembahasan ini adalah persyaratan umum yang harus dipenuhi untuk memberi pelayanan minimum kepada kendaraan dan pengguna rest area. Michi no Eki adalah sebuah konsep rest area yang menyediakan tempat beristirahat nyaman dan layanan berkualitas lainnya bagi pengguna jalan, dengan melibatkan peran serta masyarakat lokal.
KONSEP PERENCANAAN PERUMAHAN NELAYAN DI PANTAI POHUWATO PENDEKATAN PADA ARSITEKTUR VERNACULAR
Authors: Miah Nurmiah 
Published: February 2021

Nelayan merupakan kelompok masyarakat yang mata pencahariannya sebagian besar bersumber dari aktivitas menangkap ikan dan mengumpulkan hasil laut lainnya. Ini merupakan aktifitas keseharian, untuk tipe Nelayan dibedakan menjadi tiga kelompok, yaitu nelayan buruh, nelayan juragan dan nelayan perorangan. Pola aktifitas dan tipe ini sangat mempengaruhi akan model bangunan dan pola visual fungsi bangunan pada suatu kawasan Kehidupan permukiman nelayan selalu di indentikkan dengan kumuh salah satu faktor adalah kemiskinan merupakan suatu masalah yang bersifat multi dimensional, dalam arti berkaitan dengan aspek sosial, ekonomi,budaya, politik dan aspek lainnya. kemiskinan merupakan masalah dalam pembangunan yang ditandai dengan pengangguran dan keterbelakangan, yang kemudian meningkat menjadi ketimpangan. Sebagai suatu masyarakat yang tinggal di kawasan pesisir, masyarakat memiliki karakteristik sosial tersendiri yang berbeda dengan masyarakat yang tinggal di wilayah daratan. Di beberapa kawasan pesisir yang relatif berkembang pesat, struktur masyarakatnya bersifat heterogen, terbuka terhadap perubahan dan interaksi sosial. Hal ini menjadikan facade dan arah perencanaan kawasan yang tidak terarah antara bangunan lama dan bangunan baru yang tumbuh di kawasan ini . Sehingga dalam penelitian ini saya menganilisis untuk mendapatkan konsep perencanaan kawasan yang tepat bagi perumahan nelayan khususnya pada facade bangunan apakah pendekatan nilai nilai vernakular bisa di terapkan pada perencanaan kawasan rumah nelayan ini khususnya di rumah nelayan desa pohuwato timur
Rancangan Kawasan Kota Tua Teluk Betung Selatan Sebagai Destinasi Wisata Kota Bandar Lampung
Authors: Octadinata Andyzon , Persada Citra , Prasetyo Endro 
Published: February 2021

The Design Area Of South Teluk Betung Old Town As Tourism Destination
In Bandar Lampung City
Bandar Lampung City has an old town area which is located in the South Teluk Betung District. This town has existed since 1839, and the area is a center of trade and services which became the forerunner to the formation of the Capital of Bandar Lampung before being moved to Tanjung Karang. The South Teluk Betung Old Town area has heritage buildings with some variety of architectural styles such as: Thay Hin Bio Temple with Chinese architecture style, Jami "Al-Anwar Mosque with Islamic architecture style, and several houses and shophouses has been built with Indische architecture and Colonial architecture. The research method used is “Appreciative Inqury (AI)” by looking at the potentials that exist in the region. The design concept used is “heritage tourism” which is the concept of urban tourism that utilizes heritage as a tourist attraction. The design approachment is utilizing to build the environment of a city that has its own historical value. Tourists will be invited to appreciating and interpreting the heritage objects that has been observed. The results of this research is urban design elements The South Teluk Betung Old Town such as: pathways, nodes, landmarks, signage, the concept of Green Open Space, waste management, fire disaster mitigation, tsunami disaster mitigation and the concept of heritage tourism.
PENATAAN PENEMPATAN LOKASI PAPAN PETUNJUK JALAN DAN INFORMASI (SIGNAGE SYSTEM)
Authors: Fathona Geby , Hakim Abdul Hamid , Juwito Rizqiyah Safitri 
Published: February 2021

Bengkulu city Pantai panjang Nature park area (TWA) includes the National Tourism Development Zone (KPPN). The existence of Pantai panjang TWA in the middle of Bengkulu City is a special attraction for tourists. This study aims to achieve the main function of the Pantai panjang TWA area that is as a public space that should provide convenience for every tourist who is visiting. This research is focused on physical elements such as road signs and information. It was realized that the Pantai Panjang TWA area did not yet provide much convenience for tourists to get appropriate directions and information. Signage and information in the Pantai Panjang TWA area are expected to be a participatory communication medium based on the location of the arrangement and the suitability of the information The research method used is descriptive qualitative, quantitative and spatial (photo mapping) methods (Creswell, 2008), and in the form of literature studies, field observations, and interviews. The proper arrangement related to the placement of the points of the location of the road signs and information (signage system), it is expected that the information provided will be conveyed to tourists visiting the Pantai Panjang TWA area.
Efektifitas Pemberian Makanan Tambahan dan Konseling Gizi dalam Perbaikan Status Gizi Balita
Authors: Masri Erina , Sari Wulan Kartika , Yensasnidar Yensasnidar 
Published: February 2021

Upaya pemerintah untuk menangani masalah gizi pada balita yaitu dengan memberikan makanan tambahan berupa biskuit. Penelitian ini bertujuan untuk mengetahui perbedaan pengaruh pemberian makanan tambahan (PMT) dibandingkan dengan pemberian makanan tambahan (PMT) disertai konseling gizi terhadap status gizi anak usia 6 – 24 bulan. Penelitian ini menggunakan Quasi Eksperimental design dengan rancangan two group pretest and postest. Sampel penelitian balita gizi kurang usia 6–24 bulan di Nagari IV Koto Mudik Kabupaten Pesisir Selatan berjumlah 14 orang. Analisis data menggunakan uji paired T-Test. Hasil penelitian menunjukkan rata-rata berat badan yaitu 6,9 kg sebelum diberikan PMT. Setelah diberikan PMT pada bulan I diperoleh rata-rata berat badan 7,3 kg, 7,7 kg pada bulan II dan 8,2 kg pada bulan III perlakuan. Pada kelompok perlakuan kombinasi PMT dan Konseling Gizi, rata-rata berat badan awal 6,9 kg, terjadi peningkatan berat badan 7,3 kg pada bulan I, 7,9 kg pada bulan II dan 8,3 kg pada bulan III. Pemberian PMT saja tidak berpengaruh terhadap status gizi berdasarkan BB/U (p=,0,078). Intervensi kombinasi PMT dan Konseling Gizi berpengaruh terhadap status gizi kurang usia 6 – 24 bulan (p=0,008), akan tetapi tidak ada perbedaan pengaruh intervensi PMT dengan kombinasi PMT dan Konseling Gizi terhadap status gizi kurang usia 6 – 24 bulan (p=0,356)
Identifikasi Kasus Unwanted Pregnancy pada Remaja: Studi Fenomenologi
Authors: Suazini Esa Risi , Humaeroh Lina 
Published: February 2021

Kasus Unwanted Pregnancy di Indonesia (2010-2014) merupakan kasus tertinggi di ASEAN, yakni sekitar 32 ribu kasus atau 48 kasus/1000 kehamilan atau 17,5%. Pada tahun 2010 di Jawa Barat terdapat 12.300 kasus kehamilan yang tidak diinginkan akibat 29% hubungan seks pranikah (sekitar 3 juta remaja). Kekerasan di Garut, dalam 7 bulan pertama tahun 2019, telah terjadi 34 kasus kekerasan seksual (70% korbannya adalah anak-anak). Kasus kekerasan seksual di ranah privat menempati urutan tertinggi dalam 5 tahun terakhir (71%). Berdasarkan kategori pelaku kekerasan, 56% (1.670) dilakukan oleh pacar.Tujuan penelitian ini adalah untuk mengetahui faktor-faktor penyebab terjadinya free sex, identifikasi free sex, dan identifikasi unwanted pregnancy. Desain penelitian fenomenologi melalui wawancara mendalam dan pertanyaan terbuka.Teknik pengambilan sampel adalah purposive dan snowball, jumlah responden sebanyak 14 orang (3 responden wawancara mendalam, 11 orang menjawab pertanyaan terbuka). Teknik analisis data menggunakan Model Miles dan Huberman. Uji Kredibilitas dengan perpanjangan pengamatan dan triangulasi. Hasil penelitian menunjukkan bahwa faktor penyebab remaja melakukan seks pranikah adalah faktor internal (perasaan cinta, ingin mencoba, kontrol diri, sikap permisif dan pengetahuan kesehatan reproduksi) dan eksternal (sikap orang tua, sumber informasi, lingkungan, teman dan tempat yang aman serta berpacaran), perilaku dan gambaran keadaan kehamilan tidak diinginkan (fatner seksual multiple, frekuensi free sex 1->5 kali, kecanduan seksual, pengetahuan mengenai kehamilan responden, sikap dan perilaku responden, orang tua dan pacar menerima kehamilan dan tetap merawat kehamilan).
Kearifan Lokal Suku Anak Dalam (SAD) di Masa Pandemi Covid-19
Authors: Ridwan Muhammad , Sari Puspita 
Published: February 2021

Suku anak dalam (SAD) mengungsi kehutan di masa pandemik virus covid-19. Fenomena ini terjadi pada saat pemerintah memberlakukan social distancing. SAD di desa pelakar jaya mengungsi kehutan/kebun untuk menghindari penularan virus Covid-19. Tujuan Penelitian ini adalah untuk mengetahui latar belakang perilaku SAD masuk ke hutan dan kehidupan di masa pandemik virus Covid-19. Bahan dan metode, Jenis penelitian ini Kualitatif dengan desain Studi kasus. Jumlah informan sebanyak 10 orang, sample diambil dengan teknik Purposive sampling. Pengambilan data dilakukan dengan wawancara mendalam dan observasi. Analisis data dilakukan dengan Content Analysis. SAD ketika awal pendemic Covid-19, pergi kehutan atau kebun untuk menghindari penyakit, saat ini mereka tinggal di pondok sederhana atau sudung. SAD meninggalkan pemukiman di dasari oleh kebiasaan melangun yaitu meninggalkan rumah untuk menghindar dari suatu bahaya atau kesedihan. Kesimpulan kearifan lokal melangun mendasari perilaku mengasingan dengan pergi kehutan atau kebun disaat pandemic covid-19, untuk menghindar dari penyakit sesuai dengan pesan nenek moyang warga SAD
GEBELİKTE CİNSEL İŞLEV VE CİNSEL MEMNUNİYETİN DEĞERLENDİRİLMESİ
Authors: BİLGE Çiğdem , MECDİ KAYDIRAK Meltem , ÖNER Özlem , BALKAYA Nevin Akdolun 
Published: February 2021

Bu araştırma gebelerin cinsel işlev ve cinsel memnuniyet düzeylerini belirlemek amacıyla planlandı.
Tanımlayıcı ve ilişki arayıcı nitelikteki çalışma bir üniversite hastanesinin kadın hastalıkları ve doğum polikliniği ile doğum servisine Ağustos 2018-Şubat 2019 tarihlerinde başvuran (n=152) gebe bireylerle yürütüldü. Çalışmada Katılımcı Bilgi Formu, Kadın Cinsel Fonksiyon İndeksi ve Kadın Cinsel Memnuniyet Ölçeği kullanıldı. Araştırmadan elde edilen veriler SPSS 21 programında analiz edildi. Tanımlayıcı istatistiksel yöntemlerde; ortalama, standart sapma, frekans ve yüzde dağılımı, bağımlı ve bağımsız değişkenlerin karşılaştırılmasında ise Kruskal Wallis H Testi uygulandı.
Araştırmaya katılan gebelerin yaş ortalaması 28.27±5.41 olarak belirlendi. Gebelerin Kadın Cinsel Fonksiyon İndeksi’nden ortalama 19.95±9.96 ve Kadın Cinsel Memnuniyet Ölçeği’nden 81.23±16.17 puan aldıkları saptandı. Gebelerin trimesterlere göre Kadın Cinsel Fonksiyon İndeksi’nden aldığı toplam puan ve alt boyut puan ortalamaları karşılaştırıldığında, sadece ağrı alt boyutunda istatistiksel olarak anlamlı bir farkın olduğu bulunurken Kadın Cinsel Memnuniyet Ölçeği’nden aldığı toplam puan ve alt boyut puan ortalamaları karşılaştırıldığında, iletişim ve endişe (kişisel) alt boyutunda istatistiksel olarak anlamlı bir farkın olduğu belirlendi.
Araştırma sonucunda gebelerin 1. ve 3. trimesterde cinsel işlev bozukluğu yaşadığı bulundu. Bunun yanında gebelerin özellikle disparoniden şikayetçi olduğu tespit edildi. Ayrıca çalışmaya katılan gebelerin özellikle 1. ve 3. trimesterde daha düşük cinsel memnuniyet düzeyine sahip olduğu gözlendi.
Vaccines in Congenital Toxoplasmosis: Advances and Perspectives
Authors: Barros Mariana , Teixeira Daniela , Vilanova Manuel , Correia Alexandra , Teixeira Natercia , Borges Margarida 
Published: February 2021

Congenital toxoplasmosis has a high impact on human disease worldwide, inducing serious consequences from fetus to adulthood. Despite this, there are currently no human vaccines available to prevent this infection. Most vaccination studies against Toxoplasma gondii infection used animal models in which the infection was established by exogenous inoculation. Here, we review recent research on potential T. gondii vaccines using animal models in which infection was congenitally established. Endeavors in this field have so far revealed that live or subunit vaccines previously found to confer protection against extrinsically established infections can also protect, at least partially, from vertically transmitted infection. Nevertheless, there is no consensus on the more adequate immune response to protect the host and the fetus in congenital infection. Most of the vaccination studies rely on the assessment of maternal systemic immune responses, quantification of parasitic loads in the fetuses, and survival indexes and/or brain parasitic burden in the neonates. More research must be carried out not only to explore new vaccines but also to further study the nature of the elicited immune protection at the maternal-fetal interface. Particularly, the cellular and molecular effector mechanisms at the maternal-fetal interface induced by immunization remain poorly characterized. Deeper knowledge on the immune response at this specific location will certainly help to refine the vaccine-induced immunity and, consequently, to provide the most effective and safest protection against T. gondii vertical infection.
Effectiveness of Improved Use of Chewing Gum During Capsule Endoscopy in Decreasing Gastric Transit Time: A Prospective Randomized Controlled Study
Authors: Huang Liang , Hu Yue , Chen Fang , Liu Shan , Lu Bin 
Published: February 2021

Background/Aim: Chewing gum throughout small bowel capsule endoscopy (SBCE) increases completion rates (CRs) but decreases small bowel transit time (SBTT) and diagnostic yield (DY). We determined the effects of chewing gum early during SBCE on gastric transit time (GTT), SBTT, CR, DY, and gastroscopy intervention.Methods: We prospectively enrolled patients (ages 16–80 years) undergoing SBCE between January and June 2019. Patients were randomized to a chewing gum group (103 patients) and a control group (102 patients). Patients in the former group chewed one piece of gum for ~15 min every 30 min during the first hour of SBCE. Two gastroenterologists blinded to the study group examined the data.Results: GTT was shorter in the chewing gum group (29.0 min, interquartile range: 17.0–52.0 min) than in the control group [42.5 min (23.25–60 min); P = 0.01]. SBTT was similar in the two groups [318.5 min (239.5–421.3 min) vs. 287.0 min (216.0–386.0 min); P = 0.08]. Gastroscopy rate was lower in the chewing gum group (15.53 vs. 32.35%, P = 0.005). CR (95.15 vs. 89.22%, P = 0.114) and DY (67.96 vs. 59.80%, P = 0.224) did not differ between the groups. The number of abnormal-lesion types detected per patient was higher in the chewing gum group [1.0 (0.0–2.0) vs. 2.0 (0.0–2.0); P = 0.049].Conclusions: Chewing gum early during SBCE significantly reduced GTT and gastroscopy intervention, with no influence on SBTT (Trial number: NCT03815136).
Comparing Efficacy and Safety of Empirical vs. Guided Therapy for Non-cardiac Chest Pain: A Pragmatic Randomized Trial
Authors: Abdul Kadir Noor Purdah , Ma Zheng Feei , Abdul Hafidz Muhammad Ilham , Annamalai Chandramouli , Jayaraman Thevaraajan , Hamid Nurhazwani , Norhasliza Siti , Abd Aziz Azliani , Yusof Zurkurnai , Lee Hady , Lee Yeong Yeh 
Published: February 2021

Background: Non-cardiac chest pain is common with two-thirds due to gastroesophageal reflux disease (GERD).Objective: To evaluate the effectiveness and safety of guided vs. empirical therapy in non-cardiac chest pain.Methods: Adults with normal angiogram or stress test were randomized into either a guided or empirical group. In the guided group, after the ambulatory pH-impedance test, if GERD then dexlansoprazole 30 mg/day for 8 weeks, but if functional or hypersensitive chest pain, then theophylline SR 250 mg/day for 4 weeks. In the empirical group, dexlansoprazole 60 mg/day was given for 2 weeks. The primary outcome was global chest pain visual analog score (VAS) and secondary outcomes were Quality of Life in Reflux and Dyspepsia (QOLRAD), GERD questionnaire (GERDQ), and pH parameters, all determined at baseline, 2nd and 8th weeks.Results: Of 200 screened patients, 132 were excluded, and of 68 randomized per-protocol, 33 were in the guided group and 35 in the empirical group. For between-group analysis, mean global pain scores were better with guided vs. empirical group at 8th week (P = 0.005) but not GERDQ or QOLRAD or any of pH measures (all P &gt; 0.05). For within-group analysis, mean QOLRAD improved earliest at 8th week vs. baseline (P = 0.006) in the guided group and 2nd week vs. baseline (P = 0.011) in the empirical group but no differences were seen in other secondary outcomes (P &gt; 0.05). No serious adverse events were reported.Conclusions: Guided approach may be preferred over short-term empirical therapy in symptom response, however QOLRAD, acid-related symptoms, or pH measures are not significantly different (trial registration ID no. NCT03319121).
Comparing Response of Sheep and Cow Milk on Acute Digestive Comfort and Lactose Malabsorption: A Randomized Controlled Trial in Female Dairy Avoiders
Authors: Shrestha Aahana , Samuelsson Linda M. , Sharma Pankaja , Day Li , Cameron-Smith David , Milan Amber M. 
Published: February 2021

Background: Sheep milk (SM) is a possible alternate dairy source for those who experience digestive symptoms with cow milk (CM). While both the milks contain lactose, one of the causes for self-reported intolerance to CM, the composition of SM and CM also differs across proteins and fats, which have been shown to impact digestive processes.Objective: To compare the acute digestive comfort and lactose malabsorption of SM to CM in female dairy avoiders.Method: In a double-blinded, randomized cross over trial, 30 dairy-avoiding females (aged 20–30 years) drank 650 mL of SM or CM (each reconstituted from spray dried powder) following an overnight fast, on two separate occasions at least 1 week apart. Blood samples were collected for glucose and insulin assessment, and single nucleotide polymorphisms of the lactase (LCT) gene (C/T13910 and G/A22018). Breath H2 and visual analog scale (VAS) digestive symptom scores were recorded at fasting and regular intervals over 4 h after ingestion.Results: Eighty percentage of study participants were lactase non-persistent (LNP; CC13910 and GG22018 genotype). Digestive symptoms, including abdominal cramps, distension, rumbling, bloating, belching, diarrhea, flatulence, vomiting, and nausea, were similar in response to SM and CM ingestion (milk × time, P &gt; 0.05). Breath H2 was greater after CM than SM (72 ± 10 vs. 43 ± 6 ppm at 240 min, P &lt; 0.001), which may be due to greater lactose content in CM (33 vs. 25 g). Accordingly, when corrected for the lactose content breath H2 did not differ between the two milks. The response remained similar when analyzed in the LNP subset alone (n = 20).Conclusions: Despite a higher energy and nutrient content, SM did not increase adverse digestive symptoms after ingestion, relative to CM, although there was a reduced breath H2 response, which could be attributed to the lower lactose content in SM. The tolerability of SM should be explored in populations without lactose intolerance for whom underlying trigger for intolerance is unknown.
Design and Feasibility of a Randomized Controlled Pilot Trial to Reduce Exposure and Cognitive Risk Associated With Advanced Glycation End Products in Older Adults With Type 2 Diabetes
Authors: Lotan Roni , Ganmore Ithamar , Livny Abigail , Shelly Shahar , Zacharia Moran , Uribarri Jaime , Beisswenger Paul , Cai Weijing , Schnaider Beeri Michal , Troen Aron M. 
Published: February 2021

Introduction: Advanced glycation end products (AGEs) in diet and serum are positively correlated with chronic conditions such as type 2 diabetes and cognitive decline. Dietary reduction of AGEs was shown to reduce their level in serum and to have a beneficial effect on metabolic biomarkers. However, in part due to limitations of feasibility, clinical trials have not tested its effect on cognition in elderly. The current pilot study examines the feasibility of AGE reduction in elderly with diabetes in terms of recruitment and retention.Methods: The design is a randomized controlled pilot trial of dietary AGEs in elderly with type 2 diabetes (clinicaltrials.gov NCT02739971). Recruitment followed two stages: we first recruited participants with mild cognitive impairment (MCI), and after expanding inclusion criteria, we later recruited cognitively normal participants with subjective memory complaints (SMCs). Participants were randomized to two arms. Participants in the control arm received standard of care (SOC) guidelines for good glycemic control; those in the experimental arm, in addition to SOC guidelines, were instructed to lower their dietary AGE intake, primarily by changing their cooking methods. Participants were closely followed for dietary adherence over 6 months and evaluated before and after the intervention for adherence to the assigned diet, blood tests, cognitive performance, and brain MRI.Results: Seventy-five participants (52 with MCI and 23 cognitively normal with SMCs) were recruited primarily through mass mailing and advertising in social media websites. Seventy participants finished the study, and dropout was similar in both groups (7.5% in control vs. 5.7% in intervention, p = 0.757). The majority (57.5%) of participants in the AGEs-lowering arm showed very high adherence with the dietary guidelines.Discussion: Targeting feasible lifestyle modifications in high-risk populations could prevent substantial cases of cognitive decline. Observational evidence supports that AGEs may contribute to cognitive decline; however, the cognitive effect of reducing AGEs exposure has yet to be evaluated in a randomized controlled trial (RCT). The results of our pilot trial delineate a methodology including effective recruitment strategies, population of choice, and ways to assure high adherence during lifestyle modifications, and significantly advance progress toward a definitive and well-powered future RCT.