bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expression of genes involved in the inflammatory response in human granulosa cells in short-term in vitro culture
Authors: Kałużna Sandra , Bryl Rut , Chermuła Błażej , Sibiak Rafał , Stefańska Katarzyna , Pieńkowski Wojciech , Kranc Wiesława , Jeseta Michal , Ventruba Pavel , Zakova Jana , Crha Igor , Pawelczyk Leszek , Spaczyński Robert Z. 
Published: January 2021

Abstract
The essential function of granulosa cells is to maintain the proper course of oogenesis and folliculogenesis.
The immune system is an additional local regulator of ovarian function, with cytokines necessary for the proper function of the ovaries, including the secretion of steroid hormones
This study aimed to analyze the expression of genes in human GCs in short-term primary culture and define the difference in the expression of IL1β, IL6, and TNFα genes at 48h and 72h of culture compared to the 24h control. Total RNA was isolated using the Chomczyński and Sacchi protocol. RNA samples were treated with DNase I and reverse transcribed (RT) into cDNA. The determination of transcript levels of the mentioned genes was performed using the Light Cycler® 96 Real-Time PCR kit, Roche Diagnostics GmbH (Mannheim, Germany).
The present study proved that granulosa cells in a short-term primary in vitro culture express IL-1β, IL-6, and TNFα. The tested genes show a decrease in expression at 24h of culture and a subsequent slight increase at 72h, not exceeding the initial levels. The expression changes the most for IL1β and the least for TNFα.
The fluctuations in the amount of transcript may be influenced by factors stored in granulosa cells before the IVM procedure, the procedure of in vitro fertilization, as well as factors related to the process of primary culture. More research is needed to understand the details of these occurrences.

Running title: The inflammatory response in human granulosa cells
Absolute Dating of the Systematic Excavation from 2019 of the Archaeological Site: Tărtăria-Gura Luncii (Alba County, Romania)
Authors: Luca Sabin Adrian , Rustoiu Gabriel T. , Perianu Florentin , Chideșa Sergiu , Sava Tiberiu Bogdan , Păceșilă Doru , Gaza Oana , Stanciu Iuliana , Sava Gabriela , Ștefan Bianca 
Published: January 2021

Abstract
The systematic research started in 2010 at Tărtăria continue to this day. To clarify the problem of the absolute chronology of the site we have researched on a checkered row (Carriage 25-32) from the SI surface (2019) and carried out sampling for this operation. On this occasion we obtained the evidence published in this article.
Ritual deposits of the Petrești culture in South-Western Transylvania
Authors: Luca Sabin Adrian 
Published: January 2021

Abstract
This article resents archaeological discoveries of ritual pits framed in Petrești culture, discovered in western and south-western Transylvania. The ritual of consecrating the dwellings, through banquets dedicated to fertility and fecundity, is so well known at the time around the Apuseni Mountains that is spreads in cultural environments, west of them.
At the Turn of the Fourteenth Century: Sigismund of Luxemburg and the Wallachian Princely “Stars” of the Fifteenth Century
Authors: Simon Alexandru 
Published: January 2021

Abstract
In late spring 1398, the noble judges of the Inner Szolnok County rejected John Toth as the legal representative of Stephen I, voivode of Moldavia. Toth (i.e. the Slav/ Slovak, chiefly in later centuries) was in fact merely the procurator of Stephen’s appointed procurator (representative), a certain John, the son of Costea. Mircea I the Elder, the voivode of Wallachia, was experiencing similar legal problems at the time in the Voivodate of Tran-sylvania. In January 1399, his procurator, Nicholas Dobokai of Luduş, the son of Ladislas Dobokai (the relative of Mircea’s step-uncle, Wladislaw I Vlaicu), had to admit he did not know the exact boundaries of the estate of the Hunyad castle, recently granted by Sigismund of Luxemburg to Mircea. The two documents, almost trivial in essence, point towards two neglected issues: the first Transylvanian estates granted by a king of Hungary to a voivode of Moldavia and to the transalpine origins of the Hunyadi family. Placed in the context of other edited and unedited sources (charters and chronicles), the documents in question provide new perspectives on the beginnings and actions of famed Wallachian personalities of the next century.
On Pull-Back Bundle of Tensor Bundles Defined by Projection of The Cotangent Bundle
Authors: Yildirim Furkan 
Published: January 2021

Abstract
Using projection (submersion) of the cotangent bundle T*M over a manifold M, we define a semi-tensor (pull-back) bundle tM of type (p,q). The aim of this study is to investigate complete lift of vector fields in a special class of semi-tensor bundle tM of the type (p,q). We also have a new example for good square in this work.
Dichromatic polynomial for graph of a (2,n)-torus knot
Authors: Şahin Abdulgani 
Published: January 2021

Abstract
In this study, we introduce the relationship between the Tutte polynomials and dichromatic polynomials of (2,n)-torus knots. For this aim, firstly we obtain the signed graph of a (2,n)-torus knot, marked with {+} signs, via the regular diagram of its. Whereupon, we compute the Tutte polynomial for this graph and find a generalization through these calculations. Finally we obtain dichromatic polynomial lying under the unmarked states of the signed graph of the (2,n)-torus knots by the generalization.
On Some Integral Inequalities via Conformable Fractional Integrals
Authors: Akdemir Ahmet Ocak , Deniz Erhan , Yüksel Ebru 
Published: January 2021

AbstractIn the present note, we have given a new integral identity via Conformable fractional integrals and some further properties. We have proved some integral inequalities for different kinds of convexity via Conformable fractional integrals. We have also showed that special cases of our findings gave some new inequalities involving Riemann-Liouville fractional integrals.
Nonlinear optimization generating the Tomb Mural Blocks by GANS
Authors: Wu Meng , Payshanbiev Adim , Zhao Qing , Yang Wenzong 
Published: January 2021

Abstract
Tomb murals are the special kind of murals that are buried underground. Due to the narrow exit of the tomb passage, the tomb murals were excavated by dividing the whole mural into blocks, which made lots of information missing between the blocks. The digital restoration technology Image inpainting uses the edge information around the missing parts to spread the information inside of the defect area and fills the information from the outside to the inside. But it is not suitable for filling the missing parts between the tomb mural blocks. Because these parts are large for exemplar-based inpainting which may make texture dislocation and for PDE which may make cartoon blur. It is a need to generate the information outwards to complete the information. The generative adversarial network uses deep learning training by the murals remains to generate the information from inside to outside, but the typical GAN doesn‘t have a good nonlinear feature. This paper provided a generating technology based on the deep convolution generative adversarial network to rebuild the missing information between the tomb mural blocks. It built the training data set of the simulation platform with Keras and designed a whole mural generation scheme based on DCGAN. In order to get better generated results to avoid the bad artifacts; it adds the nonlinear layers by choosing 13 layers convolution and 2 deconvolution layers of the generator and contained 5 layers convolution discriminator; it designed a new phased nonlinear loss function by using Pycharm pretreatment for Numpy array file data sets; finally, it completed the generate tomb mural information to obtain the good simulation effect.
Computing Forgotten Topological Index of Extremal Cactus Chains
Authors: Cancan Murat , Imran Muhammad , Akhter Shehnaz , Siddiqui Muhammad Kamran , Hanif Muhammad Farhan 
Published: January 2021

Abstract
The F-index is the whole of 3D squares of vertex degrees in a chart G. It as of late turned into the subject of a few investigates because of its extraordinary capability of uses. The point of this paper is to register the F-record of triangular prickly plant chain, square desert flora chains, 6-sided cactus restraints and polyomino restraints. In addition, we decided the extremal chains in the desert plant chains and polyomino fastens as for the F-index.
Periodic orbits in the restricted problem of three bodies in a three-dimensional coordinate system when the smaller primary is a triaxial rigid body
Authors: Poddar Awadhesh Kumar , Sharma Divyanshi 
Published: January 2021

Abstract
In this paper, we have studied the equations of motion for the problem, which are regularised in the neighbourhood of one of the finite masses and the existence of periodic orbits in a three-dimensional coordinate system when μ = 0. Finally, it establishes the canonical set (l, L, g, G, h, H) and forms the basic general perturbation theory for the problem.
Research on style control in planning and designing small towns
Authors: Hu Xing , Li Jinhua , Aram  
Published: January 2021

Abstract
With the rapid development of extensive urbanisation in the pursuit of refined quality, the management and control of architectural features in small towns have become more and more prominent, especially in the period when the planning system is nearly complete. Most small towns are still in the low efficiency or lack of the environment has become an important obstacle to the inheritance of traditional architectural style and the shaping of individual characteristics in small towns. How to provide a refined, comprehensive and efficient building style management and control system for managers, planners and subsequent architectural designers is particularly important for reversing the current disadvantages of small town style management and control. This article is problem-centred and conducts in-depth analysis from the aspects of style control ideas and style division control, trying to find a practical way of urban style control, hoping to benefit the urban development in the modernisation boom.
Some Characterizations of Neutrosophic Submodules of an R-module
Authors: Binu R. , Isaac Paul 
Published: January 2021

Abstract
In this paper, we investigate some new characterizations in the algebraic nature of neutrosophic submodule defined over a classical module using single valued neutrosophic set. We additionally characterized the neutrosophic point and determined the algebraic properties of neutrosophic point using the operations defined on neutrosophic submodule. Finley we examined a neutrosophic set as a generator of a neutrosophic submodule and derived some related concepts.
Periodic solutions for differential systems in ℝ3 and ℝ4
Authors: Feddaoui Amina , Llibre Jaume , Berhail Chemseddine , Makhlouf Amar 
Published: January 2021

Abstract
We provide sufficient conditions for the existence of periodic solutions for the differential systems

x
′

=
y
,

y
′

=
z
,

z
′

=
−
y
−
ε
F
(
t
,
x
,
y
,
z
)
,

and

x
′

=
y
,

y
′

=
−
x
−
ε
G
(
t
,
x
,
y
,
z
,
u
)
,

z
′

=
u
,

u
′

=
−
z
−
ε
H
(
t
,
x
,
y
,
z
,
u
)
,

\matrix{{x' = y,\;\;\;y' = z,\;\;\;z' = - y - \varepsilon F(t,x,y,z),\;\;\;{\rm{and}}} \cr {x' = y,\quad y' = - x - \varepsilon G(t,x,y,z,u),\quad z' = u,\quad u' = - z - \varepsilon H(t,x,y,z,u),} \hfill \cr }

where F, G and H are 2π–periodic functions in the variable t and ɛ is a small parameter. These differential systems appear frequently in many problems coming from the sciences and the engineering.
Identification of sex using discriminant function analysis of fingerprint ridge density at three topological areas among North Indian population
Authors: Kaur Maninder , Kaur Mankamal , Yangchan Jigmath 
Published: January 2021

The present study attempted to identify sex of an individual using a fingerprint ridge density at three topological areas in the North Indian population. The study population consisted of 134 males and 136 females aged 17 to 25 years (mean age 19.34±2.12). Ridge density (RD) at radial, ulnar and proximal topological areas of the distal phalanges were determined on the surface area of 25mm2. Fingerprint ridge density in a defined area was significantly higher among females as compared to their male counterparts at radial, ulnar and proximal topological areas for both hands. Sexual dimorphic ratio also supported this trend for all three counting areas in right and left hands. Univariate discriminant function analysis explained that the left 2 radial (L2R) (88.1%) had the highest percentage of accuracy for sex identification, followed by the left 3 ulnar (L3U) (82.1%) and the right 2 ulnar (R2U) (81.6%). Multivariate discriminant function analysis showed that the radial topological area of the left hand was the best predictor of sex with the overall accuracy of 84.4%with following discriminant function equation −8.263 − 0.236(L1R) + + 0.321(L2R) + 0.269(L3R) + 0.268(L4R) − 0.067(L5R).
It can be inferred that ridge density in the radial topological area of left hand is the most reliable tool for identifying the sex of an individual.
From gerontology to geroscience: a synopsis on ageing
Authors: Chmielewski Piotr Paweł 
Published: January 2021

Biological ageing can be tentatively defined as an intrinsic and inevitable degradation of biological function that accumulates over time at every level of biological organisation from molecules to populations. Senescence is characterised by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. With advancing age, all components of the human body undergo these cumulative, universal, progressive, intrinsic and deleterious (CUPID) changes. Although ageing is not a disease per se, age is the main risk factor for the development of a panoply of age-related diseases. From a mechanistic perspective, a myriad of molecular processes and components of ageing can be studied. Some of them seem especially important and they are referred to as the hallmarks of ageing. There is compelling evidence that senescence has evolved as an emergent metaphenomenon that originates in the difficulty in maintaining homeodynamics in biological systems. From an evolutionary perspective, senescence is the inevitable outcome of an evolutionarily derived equilibrium between the amount of resources devoted to somatic maintenance and the amount of resources devoted to sexual reproduction. Single-target, single-molecule and disease-oriented approaches to ageing are severely limited because they neglect the dynamic, interactive and networking nature of life. These limitations notwithstanding, many authors promote single-target and disease-oriented approaches to senescence, e.g. repurposed drugs, claiming that these methods can enhance human health and longevity. Senescence is neither a disease nor a monolithic process. In this review, the limitations of these methods are discussed. The current state of biogerontology is also summarised.
Relationship between bone density of paranasal sinuses and adrenal steroids pattern in women during menopausal transition
Authors: Gargin Vitaliy , Muryzina Iryna , Shcherbina Nikolay , Nechyporenko Alina , Baryshevska Victoria , Vorobyova Olga , Alekseeva Victoriia 
Published: January 2021

The course of menopause transition (MT) is associated with peculiarities of alterations occurring in a woman’s body, in particular, in the structure of bone tissue. Considering that bones of the paranasal sinuses (BPNSs) play a natural defense role against the spread of dental infection, their structure is important in dentistry. However, no information was found pertaining to changes of BPNSs during MT – a time when dental maladies increase in many women.
The aim of our study was to collate density of BPNSs with status of adrenal steroids in women during MT, since the pattern of their changes determines the course of MT.
Cross-sectional associations were examined between bone density of PNSs assessed by Spiral Computed Tomography and Serum content of testosterone (T), sex hormone binding globulin (SHBG), free androgen index (FAI), insulin, dehydroepiandrosterone sulfate (DHEAS), Adione, and Adiol in 113 women of per­imenopausal age (age range from 45 to 55 years) who had already experienced premenopausal menstrual decline (amenorrhea less than 2 years).
Strong positive (r = 0.73) correlation between minimal bone density of maxillary sinus in women with level of DHEAS was detected. It is important to note, that the correlation between minimal density of the lower wall of frontal sinus is a weak positive (0.3). Therefore , it can be suggested that bone tissue of the maxillary sinus is more sensitive to changes in DHEAS.
The study showed that the level of male steroids, in particular DHEAS, affected the state of bone tissue in participants older than 50 years of age.
Assessment of GNSS PPP-Based Zenith Tropospheric Delay
Authors: Abdelazeem Mohamed , El-Rabbany Ahmed 
Published: January 2021

Abstract
This study assesses the precision of zenith tropospheric delay (ZTD) obtained through triple-constellation global navigation satellite system (GNSS) precise point positioning (PPP). Various ZTD estimates are obtained as by-products from GPS-only, GPS/Galileo, GPS/BeiDou, and triple-constellation GPS/Galileo/BeiDou PPP solutions. Triple-constellation GNSS observations from a number of globally distributed reference stations are processed over a period of seven days in order to investigate the daily performance of the ZTD estimates. The estimated ZTDs are then validated by comparing them with the International GNSS Service (IGS) tropospheric products and the University of New Brunswick (UNB3m) model counterparts. It is shown that the ZTD estimates agree with the IGS counterparts with a maximum standard deviation (STD) of 2.4 cm. It is also shown that the precision of estimated ZTD from the GPS/Galileo and GPS/Galileo/BeiDou PPP solutions is improved by about 4.5 and 14%, respectively, with respect to the GPS-only PPP solution. Moreover, it is found that the estimated ZTD agrees with the UNB3m model with a maximum STD of 3.1 cm. Furthermore, the GPS/Galileo and GPS/Galileo/BeiDou PPP enhance the precision of the ZTD estimates by about 6.5 and 10%, respectively, in comparison with the GPS-only PPP solution.
Automatic Detection of Dominant Crop Types in Poland Based on Satellite Images
Authors: Pluto-Kossakowska Joanna , Pilarska Magdalena , Bartkowiak Paulina 
Published: January 2021

Abstract
The assumption of the European Union Common Agricultural Policy is to maintain good agricultural practices for sustainability in the environment. A number of requirements are imposed on farmers, including the maintenance of permanent grassland, fallow land or crop diversification. To meet these requirements, the European Union guarantees subsidies, but at the same time fields must be monitored focusing on crop identification. The limitation of field inspection and substituting it with crop recognition using satellite images could increase the effectiveness of this procedure. The application of satellite imagery in automatic detection and identification of dominant crops over a large area seems to be technically and economically sound. The paper discusses the concept and the results of automatic classification based on a Random Forests classifier performed on multitemporal images of Sentinel-2 and Landsat-8. A test site was established in a complex agricultural structure with long and narrow parcels in the south-eastern part of Poland. Time-series images acquired during the growing season 2016 were used for multispectral classification in different configurations: for Sentinel-2 and Landsat-8 separately and for both sensors integrated. Different Random Forests approaches and post-processing methods were examined based on independent data from farmers’ declarations records, reaching the best accuracy of over 90% for crops like winter or spring cereals. Overall accuracy of the classification ranged from 72% to 91% depending on the classification variant. The elaborated scheme is novel in the context of Polish complex agricultural structure and smallholders.
A New Model of Dynamic Logic Circuit with NMOS based Keeper
Authors: Islam Riazul , Biswas Satyendra N. 
Published: January 2021

AbstractDynamic logic circuits are widely popular due to a smaller number of transistors and consume less area. But the time to switch between logics is higher due to higher contention value. A new model of the logic using nMOS based keeper circuit is proposed and the performance is evaluated using Cadence tools. Comparative results demonstrate the suitability and competency of the proposed circuit.
Generation of PWM Based on Simple Relay Feedback Systems
Authors: Zaatri Abdelouahab , Kelaiaia Ridha 
Published: January 2021

AbstractThis paper is concerned with the analysis of the tracking capability of Relay Feedback Control Systems (RFCS). The envisioned application is the generation of Pulse-Width-Modulation (PWM) with variable duty-cycle and frequency known also as Duty-Cycle Modulation. In general, two main issues have to be solved with RFCS when used for regulation and tracking. The first issue concerns the determination of autonomous self-oscillations which are generated by the closed loop. The second issue concerns the determination of the relationship between the reference and the output signals. However, if the first issue has beneficiated from different approaches and has been solved particularly in case of zero reference signal, the second issue has got insufficient theoretical results because of mathematical difficulties for obtaining analytical expressions. Considering these reasons, a deep analysis of RFCS constituted of a hysteretic relay and linear systems of first order is presented. Analytical expressions relating self-oscillations and output mean values with respect to the reference signals are obtained. The analysis of these relationships led to infer some conditions under which the relay feedback control can generate commands for regulating and tracking reference signals. It highlights also the key role played by the hysteresis band width for applications based on RFCS. Our analysis, exploiting the analytical expressions, can be used to achieve a complete design for power converters. Moreover, simulation and experiments have confirmed our results.
Model-Based Control Strategy for Autonomous Vehicle Path Tracking Task
Authors: Reda Ahmad , Vásárhelyi József 
Published: January 2021

Abstract
Despite the advanced technologies used in recent years, the lack of robust systems still exists. The automated steering system is a critical and complex task in the domain of the autonomous vehicle’s applications. This paper is a part of project that deals with model-based control strategy as one of the most common control strategies. The main objective is to present the implementations of Model Predictive Control (MPC) for an autonomous vehicle steering system in regards to trajectory tracking application. The obtained results are analysed and the efficiency of the use of MPC controller were discussed based on its behaviour and performance.