bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact des variations du prix international du pétrole sur la croissance économique au Cameroun
Authors: Saha Jean Claude , Moussa Elhadji Saidou 
Published: August 2021

Nous décomposons d’abord les variations des recettes d’exportation du pétrole du Cameroun en deux parts : l’une due aux variations du prix et l’autre due aux variations des quantités. Nous trouvons que de 1985 à 2015, 140,171 % des variations des recettes pétrolières sont dues aux variations du prix et -40,171 % aux variations des quantités. Ensuite, l’estimation d’un modèle économétrique ADRL révèle que ces variations, dues au prix, influencent positivement la croissance. Le Cameroun gagnerait à au moins stabiliser sa production du pétrole afin de se mettre à l’abris des conséquences négatives des baisses de recettes dues aux baisses de prix et d’être capable de tirer le maximum de profit des variations positives des recettes dues aux hausses du prix du pétrole.
3D Polygon Mesh Encryption Based on 3D Lorenz Chaotic Map
Authors: Alsalam Ali Nashwan , S. Rahma Abdul Monem , H. Shaker Shaimaa 
Published: August 2021

<p class="0abstract">The multimedia application developments in recent years lead to the widespread of 3D model applications. It becomes more popular in various fields as well as exchanging it over the internet. The security of the 3D models is a very important issue now a day, so the scheme for encrypting the 3D model will be proposed in this work. In this proposed scheme, the 3D polygon mesh model will be protected through the encrypting process based on a 3D Lorenz Chaotic map where the vertices value of the 3D polygon mesh model will be modified using 3D keys generated by 3D Lorenz Chaotic Map, which has excellent property and provides a good diffusion. The proposed scheme was implemented on various 3D models, which have a different number of vertices and faces. The experimental results show that the proposed scheme has good encryption results, which were noted through completely deforming and changing the whole shape of the 3D models. The Hausdorff Distance (HD) and histogram metrics are adopted to calculate the matching degree between the original and extracted model. The results show that the original and extracted model are identical through the values of HD, where they are approximately zero, and the histogram visually is identical. </p>
IL-33 Induces Sema4A Expression in Dendritic Cells and Exerts Antitumor Immunity
Authors: Suga Yasuhiko , Nagatomo Izumi , Kinehara Yuhei , Koyama Shohei , Okuzaki Daisuke , Osa Akio , Naito Yujiro , Takamatsu Hyota , Nishide Masayuki , Nojima Satoshi , Ito Daisuke , Tsuda Takeshi , Nakatani Takeshi , Nakanishi Yoshimitsu , Futami Yu , Koba Taro , Satoh Shingo , Hosono Yuki , Miyake Kotaro , Fukushima Kiyoharu , Shiroyama Takayuki , Iwahori Kota , Hirata Haruhiko , Takeda Yoshito , Kumanogoh Atsushi 
Published: August 2021

Abstract
Cancer immunotherapy has shown great promise as a new standard therapeutic strategy against cancer. However, the response rate and survival benefit remain unsatisfactory because most current approaches, such as the use of immune checkpoint inhibitors, depend on spontaneous antitumor immune responses. One possibility for improving the efficacy of immunotherapy is to promote antitumor immunity using adjuvants or specific cytokines actively. IL-33 has been a candidate for such cytokine therapies, but it remains unclear how and in which situations IL-33 exerts antitumor immune effects. In this study, we demonstrate the potent antitumor effects of IL-33 using syngeneic mouse models, which included marked inhibition of tumor growth and upregulation of IFN-γ production by tumor-infiltrating CD8+ T cells. Of note, IL-33 induced dendritic cells to express semaphorin 4A (Sema4A), and the absence of Sema4A abolished the antitumor activity of IL-33, indicating that Sema4A is intrinsically required for the antitumor effects of IL-33 in mice. Collectively, these results not only present IL-33 and Sema4A as potential therapeutic targets but also shed light on the potential use of Sema4A as a biomarker for dendritic cell activation status, which has great value in various fields of cancer research, including vaccine development.
Protein Immunization Induces Memory CD4+ T Cells That Lack Th Lineage Commitment
Authors: Sircy Linda M , Harrison-Chau Malia , Novis Camille Leite , Baessler Andrew , Nguyen Jacklyn , Hale J Scott 
Published: August 2021

Abstract
Acute viral infection generates lineage-committed Th1 and T follicular helper (Tfh) memory cells that recall their lineage-specific functions following secondary challenge with virus. However, the lineage commitment of effector and memory Th cells in vivo following protein vaccination is poorly understood. In this study, we analyzed effector and memory CD4+ T cell differentiation in mice (Mus musculus) following adjuvanted glycoprotein immunization compared with acute lymphocytic choriomeningitis virus infection. Glycoprotein immunization induced CXCR5− non-Tfh effector and memory CD4+ T cells that surprisingly had not undergone polarization toward any particular Th cell lineage but had undergone memory differentiation. However, upon challenge with virus, these Th lineage–nonpolarized memory CD4+ T cells were able to generate Th1 secondary effector cells, demonstrating their lineage plasticity. In addition, Tfh and memory Tfh cells were generated in response to protein immunization, and these cells differed from infection-induced Tfh cells by their lack of the transcription factor Tbet. Rechallenge experiments demonstrated that viral infection, but not protein immunization, during either the primary or secondary immune response, restricts the recall of Bcl6 expression and the generation of germinal center Tfh cells. Together, these data demonstrate that protein immunization generates a combination of nonpolarized memory cells that are highly plastic and memory Tfh cells that can undergo further Th1-like modulation during a secondary response to viral infection.
FcRn-Targeted Mucosal Vaccination against Influenza Virus Infection
Authors: Ochsner Susan Park , Li Weizhong , Rajendrakumar Arunraj Mekhemadhom , Palaniyandi Senthilkumar , Acharya Gyanada , Liu Xiaoyang , Wang Gefei , Krammer Florian , Shi Meiqing , Tuo Wenbin , Pauza C David , Zhu Xiaoping 
Published: August 2021

Abstract
The respiratory tract is constantly exposed to various airborne pathogens. Most vaccines against respiratory infections are designed for the parenteral routes of administration; consequently, they provide relatively minimal protection in the respiratory tract. A vaccination strategy that aims to induce the protective mucosal immune responses in the airway is urgently needed. The FcRn mediates IgG Ab transport across the epithelial cells lining the respiratory tract. By mimicking this natural IgG transfer, we tested whether FcRn delivers vaccine Ags to induce a protective immunity to respiratory infections. In this study, we designed a monomeric IgG Fc fused to influenza virus hemagglutinin (HA) Ag with a trimerization domain. The soluble trimeric HA-Fc were characterized by their binding with conformation-dependent HA Abs or FcRn. In wild-type, but not FcRn knockout, mice, intranasal immunization with HA-Fc plus CpG adjuvant conferred significant protection against lethal intranasal challenge with influenza A/PR/8/34 virus. Further, mice immunized with a mutant HA-Fc lacking FcRn binding sites or HA alone succumbed to lethal infection. Protection was attributed to high levels of neutralizing Abs, robust and long-lasting B and T cell responses, the presence of lung-resident memory T cells and bone marrow plasma cells, and a remarkable reduction of virus-induced lung inflammation. Our results demonstrate for the first time, to our knowledge, that FcRn can effectively deliver a trimeric viral vaccine Ag in the respiratory tract and elicit potent protection against respiratory infection. This study further supports a view that FcRn-mediated mucosal immunization is a platform for vaccine delivery against common respiratory pathogens.
Spectrum of Cervical Epithelial Abnormalities in Immune Surveillance Patients and its Association with CD4 Count
Authors: Baveja Puneet , Singh Sharanjit , Yadav Arun Kumar 
Published: August 2021

Background:
Cervical cancer is the fourth most common cancer worldwide. It is well-known that cervical carcinoma progresses from a preinvasive disease, which can be picked up easily by routine cervical smear examination. Studies have shown that dysplasia is five times more common in females with human immunodeficiency virus (HIV) than in healthy controls. This study aimed to find if any association existed between CD4 count, viral load, parity, hemoglobin level, age at first childbirth, duration of highly active antiretroviral therapy, and cervical epithelial abnormalities.

Methods:
The present study was a 4-year retrospective study conducted in the Department of Pathology at a tertiary care hospital of Western Maharashtra. The liquid-based Pap smear slides of HIV patients reported during the period were retrieved and reviewed. The data collected were tabulated and analyzed using the SPSS software. Statistical test was used to find an association between various clinicopathological variables and smear findings.

Results:
Pap smear abnormalities were found in 14% of the patients. The present study found a statistically significant association between Pap smear abnormalities and CD4 count, viral load, and the hemoglobin level of the patient.

Conclusion:
There is a high prevalence of Pap smear abnormalities in HIV-positive patients. CD4 count, hemoglobin level, and viral load can be used as surrogate markers for deciding the frequency of Pap smear in HIV patients.
Some results on the Flynn–Poonen–Schaefer conjecture
Authors: Eliahou Shalom , Fares Youssef 
Published: August 2021

AbstractFor
$c \in \mathbb {Q}$
, consider the quadratic polynomial map
$\varphi _c(z)=z^2-c$
. Flynn, Poonen, and Schaefer conjectured in 1997 that no rational cycle of
$\varphi _c$
under iteration has length more than
$3$
. Here, we discuss this conjecture using arithmetic and combinatorial means, leading to three main results. First, we show that if
$\varphi _c$
admits a rational cycle of length
$n \ge 3$
, then the denominator of c must be divisible by
$16$
. We then provide an upper bound on the number of periodic rational points of
$\varphi _c$
in terms of the number s of distinct prime factors of the denominator of c. Finally, we show that the Flynn–Poonen–Schaefer conjecture holds for
$\varphi _c$
if
$s \le 2$
, i.e., if the denominator of c has at most two distinct prime factors.
Múltiplas Vozes e Múltiplos Sentidos do Pertencimento Étnico: estudo de remanescentes indígenas Kiriris e Payayás
Authors: Souza Leila Damiana Almeida dos Santos , Souza Kleber Peixoto de 
Published: August 2021

Apresentamos nesse artigo aspectos epistemológicos que contribuem para análise da constituição da identidade étnica de um dos grupos humanos que compõe a diversidade dos remanescentes dos povos indígenas Kiriris e Payayás, no distrito de Missão do Sahy, em Senhor do Bonfim, Bahia. Metodologicamente nos valemos da história oral para nos aproximarmos dos processos constitutivos dos remanescentes indígenas e, consequentemente, contribuirmos para o fortalecimento cultural dos ascendentes dos Kiriris e Payayás que ali residem. Os resultados nos apontam que, por meio de uma ação dialógica, foi possível contribuir com o processo de construção da identidade étnica dos sujeitos envolvidos.
Epidemiology and Clinical Characteristics of Covid-19 Mortality in Jos, Nigeria
Authors: Gomerep SS , McHenry SI , Kumbak DB , Galam NY , Ogwuche JE , Bartekwa JW , Bako IB , Shehu NY , Isa SE 
Published: August 2021

Background: Coronavirus Disease 2019 mortality figures in Africa are comparatively lower than the figures in Europe, Asia and the Americas. Many reasons have been adduced for the differences which include the younger population in Africa. We therefore out set to describe the epidemiology and clinical features among in-hospital mortalities in our setting.
Methods: This was a retrospective study of all mortalities due to confirmed COVID-19 at the Jos University Teaching Hospital from April 2020 to April 2021. Descriptive statistics were used to present results and Chi Square analysis used to determine the association between morbidities, sex and ventilator use. A p-value of <0.05 was considered statistically significant.
Results: A total of 80 mortalities were recorded over the 12 month period. Sixty one (76.0%) were males. The mean age of the study population was 61 ± 15 years and twenty nine (36.3%) were aged ≤59 years. The median duration of hospitalization for in-hospital mortality was 4days (IQR 1-35). Fever; 61(76.3%), cough; 59(73.8 %) and dyspnea; 56 (70.0%) were the commonest presenting symptoms and 35(43.8%) had the three symptoms. Hypertension; 48(60.0%) and type 2 diabetes mellitus; 36(45.0%) were the commonest co-morbidities in the patients, and 31(38.8%) had at least two co-morbidities. Eighteen (22.5%) had both hypertension and diabetes mellitus. Hypertension and having two or more co-morbidities where associated with requirement for ventilator support (P <0.013 and P<0.001 respectively).
Conclusion: Fever, cough, dyspnea and two or more co-morbidities are common among COVID-19 mortalities in Jos. Efforts to quickly identify such patients and manage comorbidities are needed to reduce mortality.
Innovación en los procesos de distribución, mediante el uso de las TIC. Un estudio exploratorio en las mipymes.
Authors: Antonio Vidaña Paula Rosalinda , Martínez Navarrete Daniel , Muñoz Palacios Luz del Carmen , Ruiz López Carlos Alberto 
Published: August 2021

El presente estudio tuvo como objetivo identificar el nivel de adopción de las TIC´s en los procesos de distribución de las Micro, Pequeñas y Medianas Empresas (MIPyMES). El estudio fue concluyente de tipo descriptivo, que por tomar la muestra en un momento específico es transversal simple, aplicando una muestra de 483 encuestas en un periodo de febrero y mayo 2020, en los municipios de Orizaba e Ixtaczoquitlán. Se obtuvieron resultados, que en un 23.1% consideran que no necesitan medios como redes sociales, el 34.1% consideran no necesario el usar el servicio de paquetería, lo cual fue un punto discursivo como parte del análisis, entre otros resultados mostrados.
Penerapan Loose Parts terhadap Kreativitas Anak Usia Dini selama Belajar dari Rumah
Authors: Rohmatun Siti , Setiyani Erika , Rohfirsta Fulka , Fitamaya Dewi , Nisa Rohmatun , Nofan Zulfahmi Muhammad 
Published: August 2021

Pada masa pandemi saat ini, pembelajaran tatap muka ditiadakan digantikan dengan kegiatan BDR (Belajar Dari Rumah). Anak akan tertarik dengan kegiatan BDR apabila dikemas dalam bentuk kegiatan yang mengeksplorasi kemampuan kreativitas anak. Pembelajaran berbasis Loose Parts menjadi salah satu media yang dapat berpengaruh dalam program kreativitas anak, serta nantinya anak akan mampu berpikir kritis, analitis, kreatif, dan inovatif. Tujuan penelitian ini untuk mengetahui penerapan Loose Parts terhadap kreativitas anak saat BDR. Metode penelitian yang digunakan yaitu metode kualitatif deskriptif dengan responden peserta didik TK B di TK Pertiwi 12.08 Papasan-Bangsri Jepara yang berjumlah 20 anak. Hasil penelitian menyimpulkan bahwa anak tertarik dalam bermain dengan adanya berbagai benda-benda yang terdapat pada media Loose Parts. Mereka mampu berkreasi dengan media Loose Parts yang telah disediakan oleh orang tua, dan anak juga mampu mengembangkan kreativitas dari hasil proses bermain menggunakan Loose Parts saat BDR.
ALTERNATIF PENINGKATAN PENDAPATAN MASYARAKAT NELAYAN MELALUI OLAHAN BAKSO IKAN RUMPUT LAUT SEBAGAI INOVASI MAKANAN SEHAT DAN RENDAH LEMAK DI DESA TOROKEKU KECAMATAN TINANGGEA KABUPATEN KONAWE
Authors: Abdullah Sukmawati , Bunyamin Bunyamin , Buana Tjandra , Wianti Nur Isiyana , Suriana Suriana , Wunawarsih Ima Astuty , Nasser Gamal Abdel 
Published: August 2021

Kegiatan pengabdian kepada masyarakat yang berjudul “Alternatif Peningkatan Pendapatan Masyarakat Nelayan Melalui Olahan Bakso Ikan Rumput Laut Sebagai Inovasi Makanan Sehat Dan Rendah Lemak Di Desa Torokeku Kecamatan Tinanggea Kabupaten Konawe Selatan” bertujuan untuk mengetahui kondisi sosial ekonomi masyarakat di Desa Torokeku, mengetahui bagaimana peningkatan pendapatan masyarakat nelayan melalui olahan bakso ikan rumput laut sebagai inovasi makanan sehat dan rendah lemak di Desa Torokeku, dan mengetahui proses pengolahan bakso ikan rumput laut. Metode pelaksanaan kegiatan pengabdian melalui 3 tahapan yaitu tahap persiapan, pelaksanaan pelatihan, dan tahapan evaluasi. Hasil pelatihan diharapkan peserta pengabdian tertarik mengikuti pelatihan-pelatihan diversifikasi olahan bakso ikan rumput laut, sehingga dapat membuka wawasan khalayak sasaran yang memiliki kemampuan untuk mengolah hasil-hasil laut yang ada di lokasi mereka khususnya rumput laut dan mampu memasarkan produk yang dihasilkan, bahkan dapat dapat dipasarkan secara online melalui penggunaan atau pemanfaatan media elektronik atau internet sehingga mampu menjangkau pasar yang lebih luas dengan biaya rendah, dan pada sasaran kegiatan adalah terbentuknya kemandirian mitra dalam hal jaringan pemasaran, secara lebih luas, sehingga mitra memiliki media promosi produk aneka olahan ikan dalam bentuk brosur/leaflet, CD promosi, serta website, aneka olahan bakso ikan rumput laut yang diproduksi oleh mitra dapat dikemas dengan kemasan sesuai standar kemasan, proses produksi pembuatan olahan bakso ikan rumput laut dapat terjaga higienisnya dengan peralatan khusus untuk pembuatan olahan bakso ikan rumput sehingga sasaran kegiatan hasilnya berdampak pada peningkatan pendapatan dan kesejahteraan keluarga.
ANALISIS INTEGRASI PASAR KOPI DI KABUPATEN GARUT
Authors: Mulyana Tatang 
Published: August 2021

Dalam perdagangan komoditas pertanian yang efisien maka harga yang terjadi di kota kabupaten maupun antar kota kecamatan bahkan sampai desa akan terintegrasi, dan pergerakan harga akan bersifat simetri. Pada kenyataannya dalam dunia agribisnis ada kekuatan pasar oligopoli (pedagang besar propinsi) yang mengendalikan harga. Kekuatan pasar dapat pula ditentukan oleh kekuatan monopsoni ataupun oligopsoni (para pedagang besar kabupaten) karena memiliki pangsa pasar yang sangat besar. Penelitian ini bertujuan untuk mengetahui apakah perubahan harga di tingkat eceran di kota kabupaten terintegrasi dengan perubahan harga di tingkat petani di desa. Metoda penelitian yang digunakan menggunakan pendekatan kuantitatif yaitu analisis integrasi pasar dan transmisi harga. Elastisitas transmisi menghitung apakah laju perubahan harga di tingkat eceran akan ditransmisikan ke tingkat petani. Hasil penelitian menunjukkan bahwa berdasarkan elastisitas transmisi, laju perubahan harga di tingkat petani lebih kecil daripada laju perubahan harga di tingkat pengecer, baik untuk pasar local kecamatan maupun pasar pusat kabupaten. Berdasarkan nilai IMC (index of market conection), nilainya lebih besar dari satu artinya pasar di tingkat petani pada kecamatan contoh kurang terintegrasi dengan pasar lokal kecamatan dan pasar pusat di kabupaten. Kata kunci : Integrasi harga, transmisi harga, kopi
Phytochemical, Proximate and Mineral Composition of Gmelina arborea Fruits (White Teek).
Authors: Lawal A T 
Published: August 2021

The minerals and nutritional values of leaves, fruits and seeds of many plants have been reportedÂ Â to vary, depending on factors like generic background, location, environmental and cultivation methods. Thus, phytochemical, proximate and mineral compositions of Gamelina arborea (G. aborea ) fruits from Kaduna state in North central part of Nigeria were assessed using standard analytical procedures.Â Â Qualitative phytochemical screening revealed that the fruit contained tarnnis, phenols, flavinods, saponins, reducing sugar and anthraquinones. The analysed G. aborea contained 7.30 % w/w ash, 5.00% w/w moisture, 5.31% w/w fat, 4.30% w/w fibre, 2.00% w/w protein and 75.00% w/w carbohydrate while its mineral compositions (mg/100g) were shown to containÂ Na (21.70Â±1.00); Ca (29.70 Â±2.00), K(14.50Â±1.50), P (10.36Â±0.90), N (0.18Â±0.00),Â Cu (9.40Â±0.08),Â andÂ Mn (21.70Â±1.00).Â Therefore, this finding accounts for the use of G. arborea as supplement for minerals in animal feeds.
Peningkatan Literasi Perbankan Syariah Bagi Pelajar Sekolah Di Desa Bontolanra Takalar
Authors: Astuti Niken Probondani , Razak Nurlaely , Djaharuddin Dharmawaty 
Published: August 2021

Kegiatan pengabdian kepada masyarakat ini dilaksanakan sebagai upaya untuk mengedukasi perbankan syariah pelajar Sekolah Menengah Atas melalui kegiatan literasi perbankan syariah. Hal ini dilatarbelakangi dengan kenyataan bahwa kegiatan edukasi yang dilakukan selama ini untuk meningkatkan literasi keuangan syariah masih belum tersosialisasi dengan baik dan belum bisa menyentuh pelajar sekolah khususnya didaerah pedesaan.
Sasaran pengabdian ini adalah pelajar sekolah SMA Nursya Galesong di Takalar. Materi yang akan disampaikan adalah pengenalan lembaga perbankan syariah. Kegiatan pengabdian akan dilaksanakan dalam bentuk sosialisasi. Kegiatan pengabdian telah dilaksanakan dalam beberapa tahap; koordinasi persiapan pelaksanaan, pelaksanaan kegiatan edukasi, dan kegiatan evaluasi kegiatan. Kegiatan pengabdian diikuti 37 pelajar. Kegiatan pengabdian kepada masyarakat dapat meningkatkan literasi keuangan syariah peserta. Hal ini ditunjukkan dengan semakin pahamnya peserta mengenai perbedaan bank syariah dan bank konvensional, konsep dasar keuangan syariah dan akad-akad yang digunakan untuk pengembangan produk lembaga keuangan syariah.
Pelatihan Statistika Dengan Software R Studio Bagi Masyarakat Kota Makassar
Authors: Bakri Rizal , Halim Ardiansyah 
Published: August 2021

Kegiatan pengabdian pada masyarakat ini bertujuan untuk memberikan pelatihan mengolah data statistik menggunakan software R Studio. R Studio merupakan software Statistika yang populer, lengkap, dan berlisensi gratis sehingga peneliti dapat terhindar dari tuntutan hukum saat mengolah dan menganalisis data. Software ini memiliki visualisasi grafik yang lebih canggih dibandingkan software statistika lainnya. Selain itu, R Studio juga dapat digunakan dalam pembuatan aplikasi berbasis desktop maupun website.
Metode kegiatan pengabdian masyarakat ini menggunakan metode ceramah, demonstrasi langsung dipraktekkan oleh peserta, serta tanya jawab. Metode ceramah digunakan untuk menyampaikan pengetahuan secara umum tentang manfaat statistika dalam olah data, teori dasar statistik, dan pengenalan software. Demonstrasi digunakan untuk memberikan keterampilan langsung mengenai teknik-teknik olah data dengan berbagai kasus penelitian. Tanya jawab digunakan untuk melengkapi hal-hal yang belum terakomodasi oleh kedua metode di atas. Pelatihan ini melibatkan seluruh tingkat akademisi Kota Makassar yang terdiri dari Dosen, Peneliti, Karyawan, dan Mahasiswa.
Hasil pelatihan olah data statistik dapat dinyatakan berhasil. Hal ini dapat dilihat dari: (1) Kehadiran peserta sesuai dengan terget yaitu 82% (82 dari 100 Peseerta) (2) Hasil pelatihan dinyatakan sangat baik yang ditandai dengan banyaknya peserta yang paham dan beberapa dosen mengajak kerjasama untuk melakukan pelatihan di instansinya (3) Peserta sangat antusias mengikuti pelatihan yang dilihat dari keseriusan mengikuti pelatihan dan banyaknya peserta yang melakukan konsultasi setelah pelatihan.