bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychopharmaka – Anwendungspraxis in Maßregelvollzug und Allgemeinpsychiatrie im Vergleich
Authors: Stübner Susanne , Yundina Elena , Mußmann Lisa , Korbmacher Julie , Brieger Peter , Steinböck Herbert 
Published: August 2021

ZusammenfassungDie psychopharmakologische Anwendungspraxis in Maßregelvollzug und Allgemeinpsychiatrie sollte vergleichend untersucht werden.Die Medikamentenstichtagserhebungen 2014–2019 der Pharmakoepidemiologie und -Vigilanz (Pharmako-EpiVig) des Bayerischen Institut für Daten, Analysen und Qualitätssicherung (BIDAQ) aus Maßregelvollzug (n = 4590) und Allgemeinpsychiatrie (n = 5136) des Isar-Amper-Klinikums München Ost wurden ausgewertet.Mittleres Alter und Diagnoseverteilung der Patientenklientele unterschieden sich, ferner Substanzauswahl und Dosierung, die im Maßregelvollzug nahezu durchweg höher lag. Bei schizophren erkrankten forensischen Patienten wurde am häufigsten Clozapin gegeben. In beiden Fachbereichen fiel die häufige Anwendung von Valproat auf.Die Ergebnisse könnten als Hinweis gewertet werden, dass forensische Patienten schwerere und therapierefraktärere Erkrankungen aufweisen, und dass in der klinischen Praxis insgesamt eine symptombezogene antiaggressive Behandlung bedeutsam scheint.
Facile Access to Triazole-Fused 3,1-Benzoxazines Enabled by Metal-Free Base-Promoted Intramolecular C–O Coupling
Authors: Kotovshchikov Yury N. , Tatevosyan Stepan S. , Latyshev Gennadij V. , Lukashev Nikolay V. , Beletskaya Irina P. 
Published: August 2021

AbstractA convenient approach to assemble 1,2,3-triazole-fused 4H-3,1-benzoxazines has been developed. Diverse alcohol-tethered 5-iodotriazoles, readily accessible by a modified protocol of Cu-catalyzed (3+2)-cycloaddition, were utilized as precursors of the target fused heterocycles. The intramolecular C–O coupling proceeded efficiently under base-mediated transition-metal-free conditions, furnishing cyclization products in yields up to 96%. Suppression of the competing reductive cleavage of the C–I bond was achieved by the use of Na2CO3 in acetonitrile at 100 °C. This practical and cost-effective procedure features a broad substrate scope and valuable functional group tolerance.
Placental Findings in Preterm and Term Preeclampsia: An Integrative Review of the Literature
Authors: Pietro Luciana , Guida José Paulo de Siqueira , Nobrega Guilherme de Moraes , Antolini-Tavares Arthur , Costa Maria Laura 
Published: August 2021

Abstract
Introduction Preeclampsia (PE) is a pregnancy complication associated with increased maternal and perinatal morbidity and mortality. The disease presents with recent onset hypertension (after 20 weeks of gestation) and proteinuria, and can progress to multiple organ dysfunction, with worse outcomes among early onset preeclampsia (EOP) cases (< 34 weeks). The placenta is considered the root cause of PE; it represents the interface between the mother and the fetus, and acts as a macromembrane between the two circulations, due to its villous and vascular structures. Therefore, in pathological conditions, macroscopic and microscopic evaluation can provide clinically useful information that can confirm diagnosis and enlighten about outcomes and future therapeutic benefit.
Objective To perform an integrative review of the literature on pathological placental findings associated to preeclampsia (comparing EOP and late onset preeclampsia [LOP]) and its impacts on clinical manifestations.
Results: Cases of EOP presented worse maternal and perinatal outcomes, and pathophysiological and anatomopathological findings were different between EOP and LOP placentas, with less placental perfusion, greater placental pathological changes with less villous volume (villous hypoplasia), greater amount of trophoblastic debris, syncytial nodules, microcalcification, villous infarcts, decidual arteriolopathy in EOP placentas when compared with LOP placentas. Clinically, the use of low doses of aspirin has been shown to be effective in preventing PE, as well as magnesium sulfate in preventing seizures in cases of severe features.
Conclusion The anatomopathological characteristics between EOP and LOP are significantly different, with large morphological changes in cases of EOP, such as hypoxia, villous infarctions, and hypoplasia, among others, most likely as an attempt to ascertain adequate blood flow to the fetus. Therefore, a better understanding of the basic macroscopic examination and histological patterns of the injury is important to help justify outcomes and to determine cases more prone to recurrence and long-term consequences.
An inertial piezoelectric actuator with small structure but large loading capacity
Authors: Cao Yinghua , Xu Zhi , You Linjing , Wu Yaxuan , Huang Hu 
Published: August 2021

For inertial piezoelectric actuators, there generally exists a contradiction between the structure size and loading capacity, i.e., large loading capacity requiring a large structure size. To address this issue, a novel inertial piezoelectric rotary actuator with the size of 30 × 30 × 30 mm3 was proposed. Its structure and working principle were discussed in detail, followed by characterizing its output performances under various driving voltages, frequencies, and vertical loads. The results indicated that this actuator achieved good forward and reverse motion consistency. Under 100 V, it obtained the maximum angular speed of 302 007 µrad/s at about 600 Hz; especially, at 10 Hz, its vertical loading capacity was over 6700 g, being significantly higher than many previous inertial actuators with the similar size.
Priming COVID-19 salience increases prejudice and discriminatory intent against Asians and Hispanics
Authors: Lu Yao , Kaushal Neeraj , Huang Xiaoning , Gaddis S. Michael 
Published: August 2021

Significance
This study investigates whether the COVID-19 pandemic has aggravated prejudice and discrimination against racial/ethnic minority groups. Results from a nationally representative survey experiment about roommate selection suggest that incidents of anti-Asian hostility reported in the media are not isolated acts but signal-amplified racism against East Asians. While popular rhetoric has blamed East Asians for the pandemic, we find that COVID-19–associated discrimination has spilled over to South Asians and Hispanics, suggesting a generalized phenomenon of xenophobia. Prejudice fueled by COVID-19 against Asians has been particularly widespread, but for Hispanics, such negative sentiments are mitigated by respondents’ prior social contact with them. These findings highlight the need to develop a multitargeted approach to address racism and xenophobia associated with COVID-19.
Global kidney chains
Authors: Nikzad Afshin , Akbarpour Mohammad , Rees Michael A. , Roth Alvin E. 
Published: August 2021

Significance
Kidney failure is among the leading causes of death worldwide, and the best treatment is transplantation. However, transplants are in short supply because of shortfalls of transplantable organs and of finances. In the United States and some other countries, kidney exchange chains have emerged as a way to increase the number of transplants; patients who have a willing donor but cannot receive that donor’s kidney can each receive a compatible kidney from another patient’s intended donor. Such programs are much better developed within the borders of wealthy countries, which is of little help to patients in countries with limited kidney transplantation or exchange. This paper proposes and analyzes a way to extend kidney exchange chains to share the benefits globally.
Y yo en plan: “¿Qué es esto?”:
Authors: Grutschus Anke 
Published: August 2021

AbstractaEl presente artículo tiene por objeto los marcadores de citacomoyen plan, a los que no se ha prestado suficiente atención hasta el momento. Pretende describir el empleo de los dos marcadores en un corpus de habla auténtico, comparándolos según criterios como la autenticidad presumida del enunciado referido, su marcación prosódica o la introducción de contenidos no verbales. Además, se tienen en consideración los valores semánticos en los que se origina la función citativa de los marcadores, para lo cual se contrasta un significado de aproximación a un matiz ejemplificador.
Quantum droplets in a dipolar Bose gas at a dimensional crossover
Authors: Zin Paweł , Pylak Maciej , Wasak Tomasz , Jachymski Krzysztof , Idziaszek Zbigniew 
Published: August 2021

Abstract
We study the beyond-mean-field corrections to the energy of a dipolar Bose gas confined to two dimensions by a box potential with dipoles oriented in plane such that their interaction is anisotropic in the two unconfined dimensions. At a critical strength of the dipolar interaction the system becomes unstable on the mean field level. We find that the ground state of the gas is strongly influenced by the corrections, leading to formation of a self-bound droplet, in analogy to the free space case. Properties of the droplet state can be found by minimizing the extended Gross–Pitaevskii energy functional. In the limit of strong confinement we show analytically that the correction can be interpreted as an effective three-body repulsion which stabilizes the gas at finite density.
Digital material science for industrial companies
Authors: Stoyanova M V , Novikov A D , Morozov S A , Brom A E 
Published: August 2021

Abstracts
Today, the main tool for the development of any technical product made of traditional materials (metals for example) is computer-aided design (CAD) systems. CAD means a wide range of solutions that allow you to solve almost all design problems, from creating drawings to logistics. However, the engineering software visualization methods have not undergone major changes over the past decades and do not take into account the composite materials feature, and to improve the development process, it is rational to apply virtual reality technologies.
Increasing the resistance to interlayer shear of composite materials due to the modification of carbon fabric fibers with carbon nanotubes
Authors: Tarasov V A , Galinovskiy A L , Boyarskaya R V , Romanenkov V A , Boyarskiy D S 
Published: August 2021

Abstract
Interlaminar shear strength is an important characteristic of the characteristics of composite structures. This article presents the results of an experimental study of the role of carbon nanotube reinforcement of a fibrous filler of carbon fabrics in increasing the interlayer shear strength of composite articles made of carbon fiber reinforced plastics. Studies were conducted using dry roving carbon twill weave (Twill type grade: 3K, 2 x 2 Twill Weave Carbon Fiber Fabric, 5.7 Oz/Sq Yd, 50 “Wide,.012” Thick, and 3K, 2 x 2 Twill Weave).The creation of carbon composite materials based on a polyester matrix with additional reinforcement using grown carbon nanotubes (CNTs) on filler fibers has been proposed and investigated. It is shown that with a uniform distribution of CNTs on filler fibers, the interlayer shear resistance increases by 60%.
To the question of the vibroacoustic methodology for the development of carbon plastics’ diagnostics
Authors: Galinovskiy A L , Bochkarev S V , Salnikov A F , Yanko M A , Glotova M P 
Published: August 2021

Abstract
This article describes in detail the process of creating panels from a composite material by the method of vacuum infusion with various types of defects pre-installed in them. The most common types of defects that can arise in parts made of composite materials as a result of a violation of the technological process, the presence of defects in the original material, in particular, reinforcing fabric, as well as defects associated with the low qualification of the master are considered. The creation of such prototypes is necessary for the development of quality control methods for products made of composite materials. A vibroacoustic diagnostic method based on the passage of acoustic waves through a composite product is considered. It is shown that it is possible to estimate the size of a defect and the depth of its occurrence in a composite material by changing the intrinsic frequency characteristics of the wave field. Experimental data on diagnosing panels with defects is presented.
Mathematical and numerical models of buckling of three-dimensional structures taking into account the thermal effect
Authors: Dimitrienko Yu I , Bogdanov I O 
Published: August 2021

Abstracts
A mathematical model of buckling of three-dimensional structures is considered, considering the thermal effect on them. The proposed methodology for studying stability consists in solving a system of three problems: thermal conductivity, quasi-static linear thermoelasticity, and, in fact, the problem of buckling theory. The first two tasks correspond to the basic state of the structure, and the third to the varied one, which occurs when the structure loses its stability. The approach described in the work allows considering the influence on the buckling of the structure not only of three-dimensional phenomena (holes, joined local element etc.) but also the influence of thermal stresses. In the study, an algorithm for solving the buckling problem is considered and a variational statement is formulated. The presented model was tested on the rod buckling problem, which showed good agreement with the results obtained in CAE ANSYS software. The modelling presented was carried out in the SMCM software, developed by SIMPLEX Scientific and Educational Centre of Bauman Moscow State Technical University.
The role of communication in a remote learning environment on the subject of «Polymer composite materials»
Authors: Guzeva T A 
Published: August 2021

Abstract
The study considers the role of communication in the standard (full-time) and remote forms of education. The research work of students with the main task of developing a new design and technological solution in the field of polymer composite materials was chosen as an object of research. The paper presents structural schemes of interaction between the student, teacher and university environment typical for different forms of learning. The university environment is represented at several scale levels. The study demonstrates that the structure of communication changes during switchover to remote learning.
Multivariate system for evaluating the glue-welded joints quality
Authors: Yu Konoplin A 
Published: August 2021

Abstract
The change in quality indicators when replacing traditional welded joints with glue-welded ones is considered. The classification of factors influencing the machines glue-welded joints destruction processes is given. The possible destruction causes are shown on the base of the glue-welded joints destruction nature analysis. The cause-and-effect relations that have the greatest impact on the quality when replacing traditional machines welded joints with glue-welded ones are established.
Optimization of the composition of polymer composite materials with hybrid matrices for the production of machine parts operating in Arctic conditions
Authors: Kosenko E A , Zorin V A 
Published: August 2021

Abstract
The results of mechanical tests of polymer composite materials with various types of hybrid matrices at negative temperatures are presented. The hybrid matrix is formed during the product forming by adding viscoelastic components to the binder of the main matrix, which retain a liquid state. Technical wax, anaerobic and organosilicon polymer materials were used as viscoelastic components of various types of hybrid matrices. Based on the test results using optimization methods, the optimal compositions of PCMs with hybrid matrices were determined for the production of parts of transport and technological machines operating in Arctic operating conditions at temperatures of -30°C and -50°C.
FIVEx: an interactive eQTL browser across public datasets
Authors: Kwong Alan , Boughton Andrew P , Wang Mukai , VandeHaar Peter , Boehnke Michael , Abecasis Gonçalo , Kang Hyun Min 
Published: August 2021

Abstract

Summary
Expression quantitative trait loci (eQTLs) characterize the associations between genetic variation and gene expression to provide insights into tissue-specific gene regulation. Interactive visualization of tissue-specific eQTLs or splice QTLs (sQTLs) can facilitate our understanding of functional variants relevant to disease-related traits. However, combining the multi-dimensional nature of eQTLs/sQTLs into a concise and informative visualization is challenging. Existing QTL visualization tools provide useful ways to summarize the unprecedented scale of transcriptomic data but are not necessarily tailored to answer questions about the functional interpretations of trait-associated variants or other variants of interest. We developed FIVEx, an interactive eQTL/sQTL browser with an intuitive interface tailored to the functional interpretation of associated variants. It features the ability to navigate seamlessly between different data views while providing relevant tissue- and locus-specific information to offer users a better understanding of population-scale multi-tissue transcriptomic profiles. Our implementation of the FIVEx browser on the EBI eQTL catalogue, encompassing 16 publicly available RNA-seq studies, provides important insights for understanding potential tissue-specific regulatory mechanisms underlying trait-associated signals.

Availability and implementation
A FIVEx instance visualizing EBI eQTL catalogue data can be found at https://fivex.sph.umich.edu. Its source code is open source under an MIT license at https://github.com/statgen/fivex.

Supplementary information
Supplementary data are available at Bioinformatics online.
Impact of Antibiotic Stewardship Rounds in the Intensive Care Setting: A Prospective Cluster-Randomized Crossover Study
Authors: Seidelman Jessica L , Turner Nicholas A , Wrenn Rebekah H , Sarubbi Christina , Anderson Deverick J , Sexton Daniel J , Moehring Rebekah W 
Published: August 2021

Abstract

Background
Few groups have formally studied the effect of dedicated antibiotic stewardship rounds (ASRs) on antibiotic use (AU) in intensive care units (ICUs).

Methods
We implemented weekly ASRs using a 2-arm, cluster-randomized, crossover study in 5 ICUs at Duke University Hospital from November 2017 to June 2018. We excluded patients without an active antibiotic order, or if they had a marker of high complexity including an existing infectious disease consult, transplantation, ventricular assist device, or extracorporeal membrane oxygenation. AU during and following ICU stay for patients with ASRs was compared to the controls. We recorded the number of reviews, recommendations delivered, and responses. We evaluated change in ICU-specific AU during and after the study.

Results
Our analysis included 4683 patients: 2330 intervention and 2353 controls. Teams performed 761 reviews during ASRs, which excluded 1569 patients: 60% of patients off antibiotics, and 8% complex patients. Exclusions affected 88% of cardiothoracic ICU (CTICU) patients. The AU rate ratio (RR) was 0.97 (95% confidence interval [CI], .91–1.04). When CTICU was removed, the RR was 0.93 (95% CI, .89–.98). AU in the poststudy period decreased by 16% (95% CI, 11%–24%) compared to AU in the baseline period. Change in AU was differential among units: largest in the neurology ICU (–28%) and smallest in the CTICU (–2%).

Conclusions
Weekly multidisciplinary ASRs was a high-resource intervention associated with a small AU reduction. The noticeable ICU AU decline over time is possibly due to indirect effects of ASRs. Effects differed among specialty ICUs, emphasizing the importance of customizing ASRs to match unit-specific population, workflow, and culture.
The Chameleon on the branches: spectral state transition and dips in NGC 247 ULX-1
Authors: D’Aì A , Pinto C , Del Santo M , Pintore F , Soria R , Robba A , Ambrosi E , Alston W , Barret D , Fabian A C , Fürst F , Kara E , Kosec P , Middleton M , Roberts T , Rodriguez-Castillo G , Walton D J 
Published: August 2021

ABSTRACT
Soft Ultra-Luminous X-ray (ULXs) sources are a subclass of the ULXs that can switch from a supersoft spectral state, where most of the luminosity is emitted below 1 keV, to a soft spectral state with significant emission above 1 keV. In a few systems, dips have been observed. The mechanism behind this state transition and the dips nature are still debated. To investigate these issues, we obtained a long XMM–Newton monitoring campaign of a member of this class, NGC 247 ULX-1. We computed the hardness–intensity diagram for the whole data set and identified two different branches: the normal branch and the dipping branch, which we study with four and three hardness–intensity resolved spectra, respectively. All seven spectra are well described by two thermal components: a colder (kTbb ∼ 0.1–0.2 keV) blackbody, interpreted as emission from the photosphere of a radiatively driven wind, and a hotter (kTdisc ∼ 0.6 keV) multicolour disc blackbody, likely due to reprocessing of radiation emitted from the innermost regions. In addition, a complex pattern of emission and absorption lines has been taken into account based on previous high-resolution spectroscopic results. We studied the evolution of spectral parameters and flux of the two thermal components along the two branches and discuss two scenarios possibly connecting the state transition and the dipping phenomenon. One is based on geometrical occultation of the emitting regions, the other invokes the onset of a propeller effect.
The history of metal enrichment traced by X-ray observations of high-redshift galaxy clusters
Authors: Flores Anthony M , Mantz Adam B , Allen Steven W , Morris R Glenn , Canning Rebecca E A , Bleem Lindsey E , Calzadilla Michael S , Floyd Benjamin T , McDonald Michael , Ruppin Florian 
Published: August 2021

ABSTRACT
We present the analysis of deep X-ray observations of 10 massive galaxy clusters at redshifts 1.05 &lt; z &lt; 1.71, with the primary goal of measuring the metallicity of the intracluster medium (ICM) at intermediate radii, to better constrain models of the metal enrichment of the intergalactic medium. The targets were selected from X-ray and Sunyaev–Zel’dovich effect surveys, and observed with both the XMM–Newton and Chandra satellites. For each cluster, a precise gas mass profile was extracted, from which the value of r500 could be estimated. This allows us to define consistent radial ranges over which the metallicity measurements can be compared. In general, the data are of sufficient quality to extract meaningful metallicity measurements in two radial bins, r &lt; 0.3r500 and 0.3 &lt; r/r500 &lt; 1.0. For the outer bin, the combined measurement for all 10 clusters, Z/Z⊙ = 0.21 ± 0.09, represents a substantial improvement in precision over previous results. This measurement is consistent with, but slightly lower than, the average metallicity of 0.315 solar measured at intermediate-to-large radii in low-redshift clusters. Combining our new high-redshift data with the previous low-redshift results allows us to place the tightest constraints to date on models of the evolution of cluster metallicity at intermediate radii. Adopting a power-law model of the form Z ∝ (1 + z)γ, we measure a slope $\gamma = -0.5^{+0.4}_{-0.3}$, consistent with the majority of the enrichment of the ICM having occurred at very early times and before massive clusters formed, but leaving open the possibility that some additional enrichment in these regions may have occurred since a redshift of 2.