bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contribution of green manufacturing for realizing business performance in Indian small and medium scale organizations (SME’s)
Authors: Singh Mahakdeep , Singh Kanwarpreet , Sethi Amanpreet Singh 
Published: August 2021

Purpose
The current manuscript is focused on evaluating the capabilities of green practices that affect various business performance (BP) parameters of small and medium scale Indian manufacturing enterprises (SME’s). This study aims to obtain multiple significant factors that influence the implementation of green practices.

Design/methodology/approach
The manuscript focuses on statistical testing of responses obtained from 168 Indian SMEs to determine the relationship between input parameters and BP parameters. This paper starts with deploying tests such as Cronbach alpha and inter-item covariance test to obtain confidence in data collected, followed by various statistical tests such as Pearson correlation, multiple regression, canonical correlation to extract various significant factors the study. Further Games-Howell post hoc test is deployed to evaluate the significant improvements in BP gained over a reasonable duration of time. Finally, a discriminant validity test is used to find out the success or failure of the organizations that participated in the survey.

Findings
This research contributes to the holistic effect of green manufacturing (GM) toward gaining improvements in terms of different BP parameters taken for the study. It has been found that various input factors such as customer attributes, adoption of new technology, social pressure and government pressure are the main parameters for GM implementation. Further, it is observed that those at the maturity phase of GM implementation are reaping higher benefits than the organizations at the transition and stability phase.

Originality/value
The current study has been accomplished in Indian SME manufacturing organizations to investigate the effects of GM implementation in the organization. Although research findings imply the effective use of green practices within the organization to reap BP parameters and improve the market’s competitive image, the study cannot be generalized and can be used as an insight for both academicians and end-users in understanding the overall achievements of GM.
Multi-level nursing workforce planning considering talent management in healthcare with a dynamic quantitative approach
Authors: Monazam Ebrahimpour Shila , Rahimnia Fariborz , Pooya Alireza , Pakdaman Morteza 
Published: August 2021

PurposeWorkforce planning must answer how many workforces, in which positions, and talents, and when each organization is needed. To find the requirements workforce, organizations need to know the organizational position and talents pools. Clarifying the number of workforces required in each pool requires attention to workforce flows, including hiring, promotion, degradation, horizontal movement, and exiting the organization. It is a dynamic issue and must be addressed over several periods over a specific duration, which adds to the complexity. According to the talent management presented in this research, all the above complex questions are answered by applying the optimal control (OC) model according to talent management presented in this research.Design/methodology/approachThis research presents a dynamic model by using a linear-quadratic optimal control model, which was solved by Pontryagin's maximum principle, to achieve an optimal number of workforce requirements for each of the positions of nursing services manager, supervisor, head nurses and nurses in the health sector according to the required talents in each position.FindingsThe results have shown that the target value of workforce numbers has been achieved in the planning period, and the validation test and sensitivity analysis justified the model by reaching the workforce planning targets.Originality/valueThis study provides a dynamic model for achieving quantitative workforce planning targets; the model presented in this manuscript has included an important qualitative factor, namely workforce talents. According to the authors' review, there is no comprehensive research devoted to workforce planning through optimal control models by attention to workforces skills.
The bonding hypothesis revisited: evidence from US class action lawsuits
Authors: Coy Jeffrey M. , Cao Kien D. , Nguyen Thuy T. 
Published: August 2021

PurposeConsistent with an “absolute bonding hypothesis,” the benefits of listing on US exchanges experienced by cross-listed firms are accompanied by an increased risk of experiencing a spillover effect due to negative news within their industry. The purpose of this study is to test this form of the bonding hypothesis by analyzing the spillover effect to cross-listed firms when class action lawsuits are filed against their industry peers.Design/methodology/approachThe bonding hypothesis is tested by analyzing the spillover effect to non-sued cross-listed firms of class action lawsuits brought against US domestic firms in the same industry. The spillover effect is identified using cumulative abnormal returns around lawsuit filing dates from 1996 to 2020. A sample of matched non-sued cross-listed and domestic peer firms is evaluated in a cross-sectional analysis to identify country and firm-level characteristics that mitigate the negative spillover effect to cross-listed firms.FindingsWhile US firms realize significantly negative abnormal returns when class action suits are filed against their industry peers, the impact to cross-listed peers is statistically insignificant. In multivariate analyses, we show that the ability of cross-listed firms to avoid this negative spillover effect is stronger for firms with greater profitability that are headquartered in countries with better shareholder protections and governance characteristics.Originality/valueResults suggest that cross-listed firms may have a level of immunization from the negative industry spillover effect of class action lawsuits and, thus, exhibit only “partial bonding” to the US market.
A fully matched dual stage CMOS power amplifier with integrated passive linearizer attaining 23 db gain, 40% PAE and 28 DBM OIP3
Authors: Gunasegaran Premmilaah , Rajendran Jagadheswaran , Mariappan Selvakumar , Yusof Yusman Mohd , Abdul Aziz Zulfiqar Ali , Kumar Narendra 
Published: August 2021

Purpose
The purpose of this paper is to introduce a new linearization technique known as the passive linearizer technique which does not affect the power added efficiency (PAE) while maintaining a power gain of more than 20 dB for complementary metal oxide semiconductor (CMOS) power amplifier (PA).

Design/methodology/approach
The linearization mechanism is executed with an aid of a passive linearizer implemented at the gate of the main amplifier to minimize the effect of Cgs capacitance through the generation of opposite phase response at the main amplifier. The inductor-less output matching network presents an almost lossless output matching network which contributes to high gain, PAE and output power. The linearity performance is improved without the penalty of power consumption, power gain and stability.

Findings
With this topology, the PA delivers more than 20 dB gain for the Bluetooth Low Energy (BLE) Band from 2.4 GHz to 2.5 GHz with a supply headroom of 1.8 V. At the center frequency of 2.45 GHz, the PA exhibits a gain of 23.3 dB with corresponding peak PAE of 40.11% at a maximum output power of 14.3 dBm. At a maximum linear output power of 12.7 dBm, a PAE of 37.3% has been achieved with a peak third order intermodulation product of 28.04 dBm with a power consumption of 50.58 mW. This corresponds to ACLR of – 20 dBc, thus qualifying the PA to operate for BLE operation.

Practical implications
The proposed technique is able to boost up the efficiency and output power, as well as linearize the PA closer to 1 dB compression point. This reduces the trade-off between linear output power and PAE in CMOS PA design.

Originality/value
The proposed CMOS PA can be integrated comfortably to a BLE transmitter, allowing it to reduce the transceiver’s overall power consumption.
Body mass index, HbA1c and serum C‐reactive protein are predictors of secondary failure in infliximab continuance for Japanese psoriasis patients: A hospital‐based retrospective case‐control study
Authors: Terui Hitoshi , Asano Masayuki , Shimada‐Omori Ryoko , Tsuchiyama Kenichiro , Takahashi Toshiya , Nasu‐Tamabuchi Mei , Hagiwara‐Takita Akiko , Kusakari Yoshiyuki , Ohtani Tomoyuki , Aiba Setsuya , Yamasaki Kenshi 
Published: August 2021

AbstractBiologics has had a great impact on psoriasis treatment as well as the life of psoriasis patients. Infliximab (IFX), one of the biologics targeting tumor necrosis factor (TNF), is the first of the biologics introduced to Japanese psoriasis patients. Many patients had benefits of IFX from initial applications and sustained remission of skin lesions and arthritis. Some, however, fall into so‐called secondary failure, in which patients become less responsive to IFX when the treatment is repeated. The mechanism of secondary failure and the background of patients with secondary failure have not been completely elucidated. To address this issue, we retrospectively evaluated psoriasis patients treated with IFX in our department. In this retrospective, single‐center, case‐control study based on the clinical record, a total of 34 patients were enrolled. We excluded 7 patients who discontinued IFX because of adverse events of IFX. We divided other 27 patients into two groups; 16 patients who kept using IFX (Continuance group); and 11 patients who switched to other treatments (Discontinuance group). Among various clinical features, body mass index (BMI), HbA1c, and serum CRP level were significantly higher in the Discontinuance group than the Continuance group. The results indicated that these three clinical features of BMI, HbA1c and serum CRP level before treatment are the predictors of successful IFX treatment and suggest that improvement of metabolic conditions contributes to avoiding secondary failure and discontinuance of IFX.
Sex estimation of the subadult ilium prior to acetabular fusion
Authors: Garvin Heather M. , Stock Michala K. , Marciniec Katherine A. , Mohamed Merna M. , Ternent Elizabeth , Cirillo Laura E. , Stull Kyra E. 
Published: August 2021

AbstractPrevious studies evaluating sexual dimorphism in subadult pelvic features present variable, and at times conflicting, conclusions. As a result, there is yet to be a consensus on whether the subadult pelvis can be used in sex estimation methods. This study aims to assess the forensic utility of ilium shape and greater sciatic notch morphology in sexing subadult pelves prior to acetabular fusion. A sample of 397 modern U.S. individuals with unfused acetabula (i.e., tri‐radiate cartilages) aged birth to 14 years was queried from a larger sample of postmortem computed tomography scans. Elliptical Fourier analyses were performed on ilium and greater sciatic notch outlines and resultant PCs were evaluated for significant effects of sex and age. Greater sciatic notch metrics were also collected. Stepwise linear discriminant function analyses with leave‐one‐out cross‐validation were performed on the PCs and metric variables. Analyses were performed on pooled samples, on age‐specific cohort samples, and on samples that iteratively removed the youngest one‐year cohort. Cross‐validated correct classification rates ranged from 57% to 65% and no patterns were observed to support an appearance and/or consistent expression of sexually diagnostic traits. Based on the results, sex estimation using these features is not recommended in pelvic remains prior to acetabular fusion, although the sample sizes of individuals over 5 years of age were limited in this study. Future studies should focus on the sexually diagnostic ability of pelvic traits in subadult samples post‐fusion of the acetabulum.
Misleading medical literature: An observational study
Authors: Olaussen Alexander , Abetz Jeremy , Qin Kirby R , Mitra Biswadev , O'Reilly Gerard 
Published: August 2021

AbstractObjectiveLanguage that implies a conclusion not supported by the evidence is common in the medical literature. The hypothesis of the present study was that medical journal publications are more likely to use misleading language for the interpretation of a demonstrated null (i.e. chance or not statistically significant) effect than a demonstrated real (i.e. statistically significant) effect.MethodsThis was an observational study of the medical literature with a systematic sampling method. Articles published in The Journal of the American Medical Association, The Lancet and The New England Journal of Medicine over the last two decades were eligible. The language used around the P‐value was assessed for misleadingness (i.e. either suggesting an effect existed when a real effect did not exist or vice versa).ResultsThere were 228 unique manuscripts examined, containing 400 statements interpreting a P‐value proximate to 0.05. The P‐value was between 0.036 and 0.050 for 303 (75.8%) statements and between 0.050 and 0.064 for 97 (24.3%) statements. Forty‐four (11%) of the statements were misleading. There were 40 (41.2%) false‐positive sentences, implying statistical significance when the P‐value was >0.05, and four (1.3%) false‐negative sentences, implying no statistical significance when the P‐value <0.05 (relative risk 31.2; 95% confidence interval 11.5–85.1; P < 0.0001). The proportion of included manuscripts containing at least one misleading sentence was 16.2% (95% confidence interval 12.0–21.6).ConclusionsAmong a random selection of sentences in prestigious journals describing P‐values close to 0.05, 1 in 10 are misleading (n = 44, 11%) and this is more prevalent when the P‐values are above 0.05 compared to below 0.05. Caution is advised for researchers, clinicians and editors to align with the context and purpose of P‐values.
Preferences, personality, aspirations, and farmer behavior
Authors: Knapp Ladina , Wuepper David , Finger Robert 
Published: August 2021

AbstractThere is a growing literature that incorporates not only economic preferences, such as risk preferences, but also personality and aspirations into economic choice models. Here, we investigate how these concepts relate to each other and can explain observed economic choices. More specifically, we explore the role of risk preferences, personality (self‐efficacy and locus of control), and aspirations for farmers’ choices to adopt preventive measures against pests, buy cropinsurance, and to be entrepreneurially active. To this end, a sample of 568 Swiss fruit growers is analyzed. We find that for the adoption of preventive measures against pests, the best predictors are the farmers’ locus of control and their aspirations. For crop insurance demand, all behavioral variables, and especially risk preferences, contribute to explain farmers’ choices. For farmers’ entrepreneurial choice, we find that locus of control and their risk preferences are the best predictors. Our results reveal considerable domain specificity of preferences, personality, and aspirations in economic choice models.
Decline in Sars‐CoV‐2 antibodies over 6‐month follow‐up in obstetrical healthcare workers
Authors: Kiefer Miranda K. , Allen Kenneth D. , Russo Jessica R. , Ma'ayeh Marwan , Gee Stephen E. , Kniss Doug , Cackovic Michael , Costantine Maged M. , Rood Kara M. 
Published: August 2021

AbstractProblemLimited data exists on the temporal trend of the Sars‐CoV‐2 immunologic response and duration of protection following natural infection. We sought to investigate the presence and duration of Sars‐CoV‐2 serum antibodies in obstetrical healthcare workers (HCW) on serial assessments over a 6‐month period, and to assess rates of vaccine acceptance and reported vaccine side effects among this cohort.Method of studyA prospective cohort study of a convenience sample of obstetrical HCWs at a tertiary hospital. Serum Sars‐CoV‐2 antibodies for Immunoglobulin G (IgG) and Immunoglobulin M (IgM) were measured longitudinally at four intervals: baseline, 4 weeks, 12 weeks, and 6 months. Participants completed voluntary surveys on COVID19 testing, high‐risk exposures, vaccine acceptance, and vaccine side effects.ResultsOne hundred twenty‐six of 150 (84%) HCWs who volunteered for participation completed all four blood draws. Prevalence of seropositive HCWs based on positive Sars‐CoV‐2 IgG antibodies increased from 2% at baseline to 31% at 12 weeks but declined to 21% by 6 months. Forty‐two percent (19/43) of the participants considered seropositive for Sars‐CoV‐2 IgG antibodies at any of the initial three blood draws converted to seronegative status at the 6‐month follow‐up. Eighty‐seven percent (72/83) of participants who responded to a follow‐up survey were willing to accept the COVID19 vaccine. Rates of acceptance did not differ by participant antibody status. Those that experienced symptoms with the first injection were more likely to have positive Sars‐CoV‐2 IgG antibodies (36.8% vs. 9.6%, p = .01).ConclusionSars‐CoV‐2 IgG antibodies wane over time and may not provide prolonged and robust immune protection. This underscores the importance of vaccination and continued research in this area while the COVID19 pandemic continues.
Advances in allergen‐specific immune cell measurements for improved detection of allergic sensitization and immunotherapy responses
Authors: van Zelm Menno C. , McKenzie Craig I. , Varese Nirupama , Rolland Jennifer M. , O’Hehir Robyn E. 
Published: August 2021

AbstractOver the past two decades, precision medicine has advanced diagnostics and treatment of allergic diseases. Component‐resolved analysis of allergen sensitization facilitates stratification of patients. Furthermore, new formulations of allergen immunotherapy (AIT) products can more effectively deliver the relevant components. Molecular insights from the identification of allergen component sensitization and clinical outcomes of treatment with new AIT formulations can now be utilized for a deeper understanding of the nature of the pathogenic immune response in allergy and how this can be corrected by AIT. Fundamental in these processes are the allergen‐specific B and T cells. Within the large B‐ and T‐cell compartments, only those that specifically recognize the allergen with their immunoglobulin (Ig) or T‐cell receptor (TCR), respectively, are of clinical relevance. With peripheral blood allergen‐specific B‐ and T‐cell frequencies below 1%, bulk cell analysis is typically insufficiently sensitive. We here review the latest technologies to detect allergen‐specific B and T cells, as well as new developments in utilizing these tools for diagnostics and therapy monitoring to advance precision medicine for allergic diseases.
Global change, novel ecosystems and the ecological restoration of post‐industrial areas: The case of a former brown coal mine in Søby, Denmark
Authors: Conradi Timo , Henriksen Maria V.J. , Svenning Jens‐Christian 
Published: August 2021

AbstractQuestionsCan multi‐decadal vegetation changes in a decommissioned brown coal mine be attributed to global‐change forcing? Given novel drivers of community assembly and ongoing global change, what are sensible restoration goals and strategies for large post‐industrial areas?LocationA decommissioned brown coal mine near Søby, central Denmark (56°01′45′′ N, 9°04′4′′ E).MethodsWe resurveyed the plant communities of the mine 31 years after an initial survey. Changes in the prevalence of exotic species and species indicator values for environmental conditions were used to link the observed vegetation changes to global change factors.ResultsThe plant communities, including their unmined reference sites, changed over the 31‐year period toward plant communities with higher proportions of exotics, nitrophilous, warmth‐ and moisture‐indicating species, and species of low foraging quality for deer. The changes are consistent with the novel drivers of community assembly at the site, such as the introduction of exotic species, increased nitrogen deposition, elevated temperatures, steadily increasing groundwater level post mining, and the massive comeback of red deer.ConclusionsThe global‐change forcing of novel plant communities suggests that it is becoming increasingly difficult to restore historical references. It may thus be more sensible to acknowledge novelty and adopt an open‐ended approach for the restoration of this and similar post‐industrial areas, e.g. using rewilding principles to promote biodiverse self‐sustaining ecosystems.
Effect of gastric pH and of a moderate CYP3A4 inducer on the pharmacokinetics of daridorexant, a dual orexin receptor antagonist
Authors: Gehin Martine , Wierdak Jolanta , Sabattini Giancarlo , Sidharta Patricia N. , Dingemanse Jasper 
Published: August 2021

AimsDaridorexant is a dual orexin receptor antagonist developed for the treatment of insomnia. The solubility of daridorexant is pH‐dependent and daridorexant has been shown to be a sensitive CYP3A4 substrate when co‐administered with moderate CYP3A4 inhibitors. The purpose of this study was to assess the effect of an increased gastric pH on daridorexant pharmacokinetics (PK) and the extent of interaction when daridorexant is co‐administered with a moderate CYP3A4 inducer.MethodsIn this prospective, single‐centre, randomized, open‐label study, 24 male subjects consecutively received four treatments, i.e., daridorexant 50 mg single dose; famotidine 40 mg single dose + daridorexant 50 mg single dose; efavirenz 600 mg once a day (o.d.) for 10 days; and daridorexant 50 mg single dose + efavirenz 600 mg o.d. for 2 days. Plasma PK parameters of daridorexant were derived by noncompartmental analysis. Standard safety and tolerability evaluations were analysed descriptively.ResultsWhen daridorexant administration was preceded by administration of famotidine, daridorexant Cmax decreased by 39%, geometric means ratio (GMR) (90% confidence interval [90% CI]): 0.61 (0.50, 0.73). AUC0‐∞ remained unchanged. In the presence of steady‐state efavirenz, daridorexant Cmax, AUC0‐∞ and t½ decreased by approximately 35% (GMR [90% CI]): 0.65 (0.54, 0.78), 61% (0.39 (0.348, 0.44), and 35% (0.65 (0.58, 0.73), respectively. tmax remained unaffected. All treatments containing daridorexant were well tolerated.ConclusionDaridorexant 50 mg can be administered concomitantly with gastric pH modifiers or with moderate CYP3A4 inducers without dose adaptation based on efficacy observed at lower doses in Phase 3 studies.
Psychosocial interventions and needs among individuals and families with Li‐Fraumeni syndrome: A scoping review
Authors: Barnett Marie , Breen Kelsey E. , Kennedy Jennifer A. , Hernandez Marisol , Matsoukas Konstantina , MacGregor Meredith 
Published: August 2021

AbstractLi‐Fraumeni syndrome (LFS), a rare cancer predisposition syndrome caused by germline mutations in the TP53 gene, is associated with significant lifetime risk of developing cancer and warrants extensive and long‐term surveillance. There are psychosocial impacts on individuals and families living with this condition, from the initial diagnosis throughout multiple stages across the lifespan, but these impacts have not been systematically reviewed and organized. The objective of this scoping review was to synthesize and characterize the literature on psychosocial screening and outcomes, educational needs, support services, and available interventions for patients and families with LFS. A systematic search of six databases was most recently conducted in August 2020: (PubMed/MEDLINE (NLM), EMBASE (Elsevier), Cochrane Library (Wiley), CINAHL (EBSCO), PsycINFO (OVID), and Web of Science (Clarivate Analytics). A total of 15 757 titles were screened, and 24 articles included. Several important themes were identified across studies: factors associated with TP53 genetic testing, LFS surveillance, psychological outcomes, and communication. Findings related to these themes were organized into age‐specific categories (age agnostic/across the lifespan, childhood, adolescence and young adulthood, and adulthood).