bluuebunny/crossref_metadata_2025_split huggingface dataset:
Karakteristik Geokimia Basal Alkali Formasi Manamas di Sungai Bihati, Baun, Pulau Timor
Authors: Widiatama Angga Jati , Santy Lauti Dwita , Natalia Happy Christin , Wahyudiono Joko , Ikhram Rinaldi 
Published: August 2021

ABSTRAK Batuan beku Formasi Manamas di Sungai Bihati, Baun merupakan salah satu singkapan batuan beku di Pulau Timor yang belum banyak diteliti berdasarkan karakter geokimia. Penelitian ini bertujuan untuk mengetahui genesa dan proses yang terjadi pada batuan beku Formasi Manamas dalam kerangka tektonik yang terjadi di Pulau Timor berdasarkan analisis petrografi dan geokimia. Analisis geokimia dilakukan dengan menggunakan X-ray Fluorescence (XRF) dan Inductively Coupled Plasma-mass Spectrometery (ICP-MS) untuk mengetahui senyawa utama, unsur jejak, dan unsur tanah jarang. Batuan beku Formasi Manamas berupa intrusi basal dengan afinitas alkali yang menunjukkan pola pengayaan unsur tanah jarang yang identik dengan Ocean Island Basalt (OIB). Penelitian ini membuktikan adanya dua mekanisme pengayaan unsur yang berbeda yaitu fluid related enrichment yang berkaitan dengan aktifitas subduksi lempeng Samudra Hindia di bawah Busur Banda dan melt related enrichment yang diperkirakan berasal dari sisa lempeng Samudra Hindia yang patah yang masuk kedalam zona reservoir OIB. Kedua magma lalu bercampur dan mengalami underplating di bawah Busur Banda. ABSTRACT The igneous rock of Manamas Formation in the Bihati River, Baun is one of the igneous rock outcrops in Timor Island that has not been widely studied based on its geochemical characteristic. This study aims to determine the genesis and processes that occur in the igneous rocks of the Manamas Formation within tectonic framework of Timor Island based on petrographic and geochemical analysis. X-ray Fluorescence (XRF) and Inductively Coupled Plasma-mass Spectrometery (ICP-MS) were used to determine the major elements, trace elements, and rare earth elements. The igneous rock of the Manamas Formation is a basalt intrusion with an alkaline affinity which shown an enrichment pattern of rare earth elements identical to Ocean Island Basalt (OIB). This study proves the existence of two different mechanisms of elemental enrichment, fluid related enrichment which related to the subduction activity of the Indian Ocean plate under the Banda Arc and also melt related enrichment which originated from the broken Indian Ocean plate which enters the OIB reservoir zone. The two different magmas then mix and underplating beneath the Banda Arc.
Mikrozonasi di Daerah Plampang, Nusa Tenggara Barat
Authors: Iswanto Eko Rudi , Riyanto Theo Alvin , Suntoko Hadi 
Published: August 2021

ABSTRAK Provinsi Nusa Tenggara Barat (NTB) merupakan daerah dengan aktivitas kegempaan yang tinggi. Fenomena ini disebabkan oleh adanya aktivitas tektonik sebagai akibat pertemuan Lempeng Eurasia-Australia (zona subduksi) di bagian selatan dan Sesar Flores di bagian utara serta adanya keberadaan sesar-sesar lokal. Terkait dengan rencana pengembangan kawasan Samota di Pulau Sumbawa, NTB, perlu dilakukan suatu kajian kegempaan. Tujuan penelitian ini adalah memetakan indeks kerentanan seismik (Kg) melalui pengukuran mikrotremor dengan analisis menggunakan metode Horizontal to Vertical Spectral Ratio (HVSR). Hasil penelitian berupa peta kerentanan seismik daerah Plampang yang menunjukkan bahwa sisi utara lokasi penelitian memiliki indeks kerentanan seismik rendah yang ditandai dengan nilai amplifikasi kurang dari tiga jika dibandingkan daerah lainnya. Geologi sisi utara lokasi penelitian tersusun oleh batuan gunung api dengan karakteristik batuan keras, ketebalan sedimen sangat tipis, dan tersusun atas batuan Tersier atau lebih tua. Peta kerentanan seismik berguna sebagai acuan dalam mitigasi gempa bumi untuk mengurangi risiko yang ditimbulkan. ABSTRACT Nusa Tenggara Barat (NTB) Province is an area with intense seismic activity. This phenomenon is caused by tectonic activity as the result of the convergency of the Eurasia-Australia Plates (subduction zone) in the south and the Flores Fault in the north as well as the presence of local faults. Regarding the plan to develop the Samota area in Sumbawa Island, NTB, a study concerning earthquakes should be done. The purpose of this study is to map the seismic vulnerability index (Kg) through microtremor measurement by using the Horizontal to Vertical Spectral Ratio (HVSR) analysis method. The result of the study is a seismic vulnerability map of the Plampang area which its northern part has a low seismic vulnerability index indicated by the amplification factor value of less than three compared to other areas. The geology of the northern part of the Plampang area consists of volcanic rocks which has hard rock characteristic, very thin sediment thickness, and composed of Tertiary or older rocks. Seismic vulnerability maps can be useful as a reference for earthquake mitigation to reduce its risks.
The role of computed and magnetic resonance imaging in assessment of the local advancement of malignant tumors of the hearing organ
Authors: Khazarova E. G. , Dronova E. L. 
Published: August 2021

Introduction. Сomputed tomography (СТ) and magnetic resonance imaging (MRI) are the main methods of radiological diagnostics, which makes it possible to objectively assess the local advancement of malignant tumors of the hearing organ and decide on the possibility of surgical intervention.The objective of this scientific research – to determine the main indications for surgical intervention, taking into account the radiological criteria for the lesion of the temporal bone (CT, MRI) in locally advanced outer ear skin cancer. Materials and methods. This research work based on a retrospective and prospective analysis case history for patients with locally advanced external ear skin cancer. These are 45 patients, who received treatment in surgical department of head and neck tumors in N. N. Blokhin National Medical Research Center of Oncology between 1994 and 2020. Patient observation time averaged 30.0 ± 32.3 months (from 0.7 to 117.4 months, median – 12.0 months).Results. The prevalence of the tumor process in cancer of the skin of the external auditory canal in accordance with the staging system for lesions of the temporal bone structures (University of Pittsburgh, 1990), which takes into account CT and MRI signs of damage to the temporal bone and adjacent anatomical structures, is a factor that significantly affects the long-term results of treatment (for disease-free survival: hazard ratio (HR) 4.76, 95 % confidence interval (CI) 1.93–11.73, р = 0.00069; for tumor-specific survival: HR 4.25, 95 % CI 1.74–10.39, р = 0.0015; for overall survival: HR 1.96, 95 % CI 1.07–3.58, р = 0.029).Conclusion. CT and MRI are mandatory methods of radiological diagnosis of patients with skin cancer of the external auditory canal.
Correction of eating disorders in patients with oral and oropharyngeal cancer after reconstructive plastic surgery
Authors: Krasavina E. A. , Choynzonov E. L. , Kulbakain D. E. , Aleekseev V. A. 
Published: August 2021

The study objective – to evaluate the feasibility of correcting eating disorders in patients undergoing surgery for oral and oropharyngeal cancers using various reconstructive techniques to restore postoperative defects.Materials and methods. Between 2012 and 2019, a total of 56 patients with stage II–IV oral and oropharyngeal cancer underwent reconstructive surgery after either hemiglossectomy or glossectomy. The patients ranged in age from 26 to 70 years. The patients were divided into two groups. Group I consisted of 36 (64.3 %) patients who underwent tongue reconstruction using rotation flaps. For reconstruction of hemiglossectomy defects, a chin flap was used, and for reconstruction of glossectomy defects, a pectoral flap was used. Group II comprised 20 (35.7 %) patients who underwent tongue reconstruction using free revascularized flaps. For the tongue reconstruction after hemiglossectomy, the radial flap, medial sural perforator flap and fasciocutaneous anterolateral thigh flap were used. For the tongue reconstruction after glossectomy, the fasciocutaneous anterolateral thigh flap was used. The acts of chewing and swallowing were restored during speech rehabilitation due to the activation and coordination of the work of the muscles of the cheeks, lips, soft palate, pharynx, and the reconstructed tongue. Eating disorders were assessed by interviewing patients. A comparative analysis of eating disorders included mobility and coordination of facial muscles and reconstructed tongue, increased sensitive in the oral cavity, the presence of aspiration and nasal regurgitation, and subjective difficulties of patients. The time before the start of rehabilitation and its duration were taken into account. Patients were interviewed before the start of the combined treatment, at the beginning and after the completion of rehabilitation.Results. After the completion of rehabilitation, all patients received food by the oral route. The best outcomes were achieved in group 2a patients, who underwent tongue reconstruction with free revascularized flaps. This group of patients had a lower percentage of the asymmetry of facial muscles and limited mobility of the tongue compared to other groups of patients.In the subgroups of patients undergoing glosssectomy, most of the studied parameters did not have statistically significant differences in values. However, it should be noted that in group 2b, the period from the date of surgical treatment to the beginning of rehabilitation was significantly longer than in group 1b.Conclusion. The use of the microvascular surgical techniques using various donor flaps creates the basis for a more complete functional recovery and expands the rehabilitation potential of patients after surgical treatment of oral and oropharyngeal cancer.
Current treatment strategy for resectable scalp and neck melanoma
Authors: Polyakov A. P. , Rebrikova I. V. , Mordovskiy A. V. 
Published: August 2021

Melanoma is a malignant skin tumor associated with a poor clinical prognosis. The incidence of melanoma is constantly rising. Several studies demonstrated that overall and relapse-free survival rates in patients with head and neck melanoma were lower than those in patients with skin melanoma of other locations. Some authors showed that patients with scalp melanoma had the worst prognosis.Surgery is currently the main treatment option for resectable skin melanoma. It has a number of specific characteristics, such as the need for a smaller resection margin at primary tumor removal in some cases, lower accuracy of sentinel lymph node identification due to the complexity of lymph flow from the scalp and neck, and changes in the standard volumes of lymphadenectomy considering lymph flow from the scalp and neck. Oncologists should have reconstructive surgery skills, because their aim is not only to ensure complete tumor excision, but also to achieve a satisfactory appearance of the patient, especially if the tumor is located in the face, open areas of the head and neck and ears, since this is of functional and aesthetic importance. The administration of adjuvant therapy still causes some controversy in cases where both radiation therapy and pharmacotherapy are indicated.In this article, we describe the main characteristics of the current treatment strategy for resectable scalp and neck melanoma and cover the main problems in this area that have not been addressed so far.
Subcutaneous emphysema and pneumomediastinum after endoscopic transnasal removal of nasopharyngeal angiofibroma
Authors: Kuznetsov M. S. , Voronov A. V. , Dvoryanchikov V. V. , Svistov D. V. , Nikitin A. I. 
Published: August 2021

Introduction. Juvenile nasopharyngeal angiofibroma is a rare, benign, well-vascularized tumor of the skull base characterized by destructive growth. The development of endoscopic techniques and experience of surgeons have enabled the removal of this tumor both at early stages and late stages (advanced disease). Patients may develop various complications in the intraoperative and postoperative periods, including massive bleeding, nasal liquorrhea, facial paresthesia, lacrimal hyposecretion, etc. Air penetration into the subcutaneous fat and mediastinum during endoscopic surgery on the paranasal sinuses is rare. Such complication as subcutaneous emphysema and pneumomediastinum after endoscopic endonasal removal of juvenile nasopharyngeal angiofibroma has not been reported in the literature.Case report. A 19-year-old male patient has undergone endoscopic endonasal removal of juvenile nasopharyngeal angiofibroma. The tamponade was removed within the first 24 h postoperatively. Ten hours after it, the patient developed subcutaneous emphysema and pneumomediastinum triggered by sneezing. The diagnosis was confirmed by computed tomography of the neck and chest. The patient was transferred to the intensive care unit and received conservative treatment (including infusion, antibacterial, and antiinflammatory therapy). The symptoms of subcutaneous emphysema and pneumomediastinum subsided in response to treatment. Follow-up examinations (computed tomography and magnetic resonance imaging) confirmed that the tumor had been completely removed. The patient was discharged in a satisfactory condition.Conclusion. Subcutaneous emphysema and pneumomediastinum are exceedingly rare complications of endoscopic endonasal removal of juvenile nasopharyngeal angiofibroma and are caused by anatomical connection between the parapharyngeal / retropharyngeal spaces and mediastinum. To prevent such complications, it is necessary to keep tampons in the nasal cavity for at least 2 days, as well as to instruct patients after surgery (avoid sneezing with their mouth closed, lifting weights, coughing, and vomiting). The nasoseptal flap used to repair the nasopharyngeal defect after tumor removal also ensures its sealing. Patients with complications should undergo computed tomography of the neck and chest (in case of emergency) and should be transferred to an intensive care unit. Conservative treatment (antibacterial and antiinflammatory therapy) will ensure good results in most patients.
Risk factors for developing epilepsy in children with cerebral pals
Authors: Mammadbayli A K , Taghiyeva M R 
Published: August 2021

Aim. To identify the most important risk factors affecting the development of epilepsy in children with cerebral palsy.
Methods. The study included 160 cerebral palsy patients with and without epilepsy who received treatment at the Baku Children's Neurological Hospital. The patients were divided into 2 groups. The first group consisted of 110 (68.7%) patients with cerebral palsy and epilepsy, and the second group consisted of 50 (31.3%) patients with cerebral palsy. The age of children ranged from 1 to 14 years. Statistical data processing was performed by using the SPSS software version 16.0. The Chi-square test was used to compare categorical measurements. T-test for independent groups was used for comparison between groups of continuous measurements. Binary logistic regression was used for determining the risk factors. In all tests, the level of statistical significance was set at p 0.05.
Results. There was no significant difference in age and gender distribution between groups (p=0.492 and p=0.818, respectively). 10 (9.1%) children in the main group had a positive family history of epilepsy (odds ratio 8.08, p=0.028). Neonatal seizures were observed in 25 (22.7%) children in the main group and 3 (6%) children in the control group (odds ratio 4.4, p=0.010). The presence of infection during pregnancy in the mother was found in both the main (39.1%) and control (20%) groups (odds ratio 2.6, p=0.018). Level IV of the Gross Motor Function Classification System (GMFCS) was the most frequent among patients with epilepsy (odds ratio 12.8; p=0.035). The incidence rate of epilepsy among cerebral palsy patients was 68.7%. The mean age of onset of seizures was 19.226.6 months. The most frequent epileptic seizures (55.5%) occurred in spastic quadriplegic cerebral palsy.
Conclusion. The presence of a positive family history of epilepsy, neonatal seizures, maternal infection during pregnancy and severe GMFCS level were identified as factors for the development of epilepsy in patients with cerebral palsy; premature birth, presence of hypoxic-ischemic injury, low birth weight, consanguineous marriage, multiple pregnancies, or gender were not identified as risk factors for the development of epilepsy in children.
Perioperative antibiotic prophylaxis for abdominal delivery at the regional perinatal center
Authors: Tashtanbekova Ch B , Evstratov A A , Chuenkova E A , Ziganshina L E 
Published: August 2021

Aim. To conduct a comparative pharmacoepidemiological study and assess the rational use of antibiotics in women undergoing caesarean section.
Methods. A retrospective analysis of 1,025 birth histories of women after planned and emergency cesarean section was carried out with a detailed assessment of the use of antibiotics in 20072009 (523) and 20162017 (502) with an interval of 10 years for which new clinical guidelines, principles of rational pharmacotherapy and evidence-based medicine were introduced. The time of administration of the first dose, duration of administration, consumption of antibiotics were assessed. The significance of differences in relative indicators was assessed according to Pearson (2).
Results. Antibiotics were prescribed to women with planned and emergency caesarean section in 100% of cases in the first period of the study (20072009) and prescribed in 98% of women with planned caesarean section and 96% with emergency caesarean section in the second period (20162017). In the first period, the first dose of antibiotic was administered: in 110 (44%) cases during surgery and 139 (56%) cases after surgery in planned caesarean section; in 139 (51%) cases during surgery and 135 (49%) cases after surgery in emergency caesarean section. In the second period, antibiotics were administered 3060 minutes before the operation in 263 (96%) cases in the planned caesarean section and 218 (95%) cases in the emergency; postoperative antibiotics were administered in 7 (2%) women in the planned caesarean section and 2 (1%) women in the emergency (p 0.05). Greater than 56 days of antibiotics were used: in 166 (67%) women in the planned operation and 166 (61%) in the emergency for the first period; in 43 (16%) women with the planned operation, and 38 (17%, p 0.05) women with an emergency for the second period. In the first period, 13 antibiotics from 8 pharmacotherapeutic groups were used and in the second period, 7 out of 5 were used.
Conclusion. From 2007 to 2017, the use of antibiotics has become to comply with the implemented clinical guidelines for abdominal delivery: the duration of antibiotic use has decreased, the time of administration of the first dose and the range of antibiotics used changed.
Analysis of antithrombotic therapy in elderly patients with nonvalvular atrial fibrillation in the Kyrgyz Republic and ways to increase treatment adherencе
Authors: Kinderbaeva N K , Bazira K , Karabekova N M , Mamatova R M , Asel Zh , Nartaeva A K , Mamatov S M 
Published: August 2021

Aim. To analyze anticoagulant therapy in elderly patients with non-valvular atrial fibrillation and ways to increase adherence in the work of a specialized team.
Methods. The study followed 250 patients with non-valvular atrial fibrillation aged 65 to 74 years (mean age 70.74.39 years). The patients were divided into three groups: the first group included 105 people, who were prescribed warfarin in a retrospective study; the second group 57 people treated with rivaroxaban, and the third group 88 people treated with warfarin. The second and third groups were prospective study groups which were supervised by a specialized team of physicians. The groups were matched on sex and age, comorbidities. Statistical data analysis and mathematical processing were performed by using the methods of descriptive and variational statistics. Most parameters reported as absolute values and percentages, while quantitative data the 25th and 75th percentiles.
Results. All patients included in the study had a high risk of developing thromboembolic complications by their CHA2DS2-VASc score (2) and a low risk of developing hemorrhagic complications on the HAS-BLED scale (average score 1.490.04). They were prescribed anticoagulant therapy. By the end of the year follow-up from the start of anticoagulant therapy, only 9.5% of patients were treatment adherent, in the second group 43.8%, in the third group 70.5% of patients. The reason for refusing to take warfarin in the vast majority of cases was the inability to control the international normalized ratio, medical contraindications, and the high cost of the drug in prescribing rivaroxaban. The results showed that the majority of patients with atrial fibrillation (90.5%) receive inadequate antithrombotic therapy in routine outpatient clinical practice. At the same time, in a very small number of patients (9.5%) receiving warfarin, this type of therapy can be considered adequate (60% or more of the stay time in the therapeutic range of international normalized ratio of 2.0 to 3.0).
Conclusion. Anticoagulant therapy prescription under the supervision of a specialized team contributes to a significant improvement in treatment adherence (from 43.8 to 70.5%); promising in the future is the use of drugs from the group of new oral anticoagulants that do not require routine monitoring of coagulogram.