bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metric Rectifiability of ℍ-regular Surfaces with Hölder Continuous Horizontal Normal
Authors: Di Donato Daniela , Fässler Katrin , Orponen Tuomas 
Published: July 2021

Abstract
Two definitions for the rectifiability of hypersurfaces in Heisenberg groups $\mathbb{H}^n$ have been proposed: one based on ${\mathbb{H}}$-regular surfaces and the other on Lipschitz images of subsets of codimension-$1$ vertical subgroups. The equivalence between these notions remains an open problem. Recent partial results are due to Cole–Pauls, Bigolin–Vittone, and Antonelli–Le Donne. This paper makes progress in one direction: the metric Lipschitz rectifiability of ${\mathbb{H}}$-regular surfaces. We prove that ${\mathbb{H}}$-regular surfaces in $\mathbb{H}^{n}$ with $\alpha $-Hölder continuous horizontal normal, $\alpha&gt; 0$, are metric bilipschitz rectifiable. This improves on the work by Antonelli–Le Donne, where the same conclusion was obtained for $C^{\infty }$-surfaces. In $\mathbb{H}^{1}$, we prove a slightly stronger result: every codimension-$1$ intrinsic Lipschitz graph with an $\epsilon $ of extra regularity in the vertical direction is metric bilipschitz rectifiable. All the proofs in the paper are based on a new general criterion for finding bilipschitz maps between “big pieces” of metric spaces.
Community pharmacists’ views on their current role and future opportunities for antibiotic stewardship: a French qualitative study
Authors: Essilini Anaïs , Pierre Amélie , Bocquier Aurélie , Pulcini Céline , Wilcke Christophe , Gravoulet Julien , Demore Béatrice , Thilly Nathalie 
Published: July 2021

Abstract

Background
Different healthcare professionals should contribute to antibiotic stewardship (ABS) activities. Involvement of community pharmacists (CPs) has been little explored worldwide to date.

Objectives
To explore French CPs’ views on ABS and antibiotic resistance, their role and current practices, and future opportunities for ABS.

Methods
A qualitative study using semi-structured face-to-face individual interviews was performed from May to October 2019 among CPs from north-eastern France. Transcripts of the interviews were analysed using a thematic analysis.

Results
Twenty-seven interviews were conducted. Most participants had a clear understanding of antibiotic resistance and ABS. They considered themselves as ‘guardians of the appropriate use of drugs’ but often failed to fulfil this mission because of difficult relationships with physicians. Their current ABS practices are: (i) counselling patients about the antibiotic treatment; and (ii) reporting to the prescriber when they identify contraindications/drug interactions. Concerning their potential increased involvement in ABS, CPs felt they could perform more rapid diagnostic testing for sore throat; they were divided on the possibility for them to change the antibiotic prescription made by a physician and were mainly against the possibility of initiating an antibiotic prescription. The idea of systematically collecting unused antibiotics was perceived well by CPs, while unit dose delivery was not.

Conclusions
French community pharmacists are willing to become more involved in ABS activities. Collaboration and trust between pharmacists and prescribers should however be improved.
Factors Affecting Willingness to Use Indoor Residual Spraying Among Pregnant Women Attending Antenatal Care in Hyperendemic State of West Africa: A Random Survey
Authors: Oladoyinbo Tunji Oloyede , Adeogun Adedapo Olufemi , Babalola Ayodele Samuel , Babatunde Muideen , Ladipo Olabode Taiwo , Olarinde Taiwo Iyabode , Oyedemi Ibrahim Dawud 
Published: July 2021

Abstract
This study assessed the perception of pregnant women on indoor residual spraying (IRS), documented acceptability, and factors that significantly dictate willingness to use IRS among the pregnant women attending antenatal clinic in Ibadan Nigeria. A structured questionnaire was used to obtain relevant information from 500 pregnant women. Descriptive and principal component analysis (PCA) were done at 5% level of significance. Majority of the pregnant women had between good and fair knowledge of IRS. Less than 70% of the respondents were willing to allow IRS in their homes. Our PCA revealed that major factors responsible for acceptance and willingness to use IRS were associated with perceived benefits, advantages, and disadvantages of IRS rather than overall knowledge of IRS among the respondents. The analysis revealed that these factors were responsible for at least 80% of the reasons for a pregnant woman to willingly accept IRS or not. The factors that positively influenced willingness to use IRS include its benefit in controlling mosquitoes and other insects, reducing malaria incidence, and prolonged effects of IRS which is an added advantage over continuous purchase of aerosols. One major factor that may negatively affect the acceptance of IRS is the fact that you may have to pack out of the house and wait for more than 3 d before entering. This current study has identified some specific factors that seem to promote and/or reduce willingness to accept IRS as a malaria control intervention among pregnant women in South Western Nigeria.
The influence of abiotic and spatial variables on woody and herbaceous species abundances in a woodland–grassland system in the Eastern Terai of India
Authors: Das Dhritiman , Banerjee Subham , Lehmkuhl John , Krishnaswamy Jagdish , John Robert 
Published: July 2021

AbstractThe environmental factors that influence tree–grass abundances in tropical savanna and grasslands are not well understood, particularly for woodland–grassland mosaics in humid zones. We studied the effects of abiotic and spatial variables on woody and herbaceous species distributions in a Terai ecosystem of northeastern India. We evaluated the importance of climatic and non-climatic factors that maintain variable tree–grass ratios across the landscape, and also accounted for spatial connectivity and dispersal. We measured species abundances of woody and herbaceous plant species in 134 plots with each 30 m × 30 m in a 519 km2 protected Terai habitat, and derived several climatic and non-climatic environmental factors. We constructed variables based on different models of spatial connectivity among sites, to test their influence on species abundances. We then used redundancy analyses and variation partitioning to quantify the importance of environmental variables and spatial structure on variation in tree–grass abundances. We found that environmental variables including rainfall, fire, water stress, topography and soil nutrients had statistically significant effects on species abundance and tree–grass ratios. Spatial structure was significant, and the best spatial model was an inverse distance-weighted model with linkage extending to 23.5 km, indicating weak dispersal limitation. About 21% of the variation in species abundance was explained by the selected environmental and spatial factors. The results indicate that dynamic plant communities in which spatial–temporal variation in environmental factors may drive stochasticity in species distribution and abundance, thus dominantly influencing on the vegetation mosaic.
Realized niche shift associated withGalinsoga quadriradiata(Asteraceae) invasion in China
Authors: Zhang Wengang , Chen Xiaoyan , Liu Ruiling , Song Xingjiang , Liu Gang , Zou Jiabin , Qian Zengqiang , Zhu Zhihong , Cui Langjun 
Published: July 2021

AbstractShifts in the realized niches of exotic species may play an important role in their invasion. Galinsoga quadriradiata has invaded China widely and occupied many climate zones that are different from its native range. We addressed the climatic niche shift of G. quadriradiata and evaluated how this could contribute to its invasion in China. We used the Maxent model to predict the potential distribution of G. quadriradiata using its native and invaded range occurrences and climatic variables. Principal component analysis was conducted to measure climatic niche shifts of G. quadriradiata during its invasion in China. The models revealed only 32.7% niche overlap between the native and invasive populations. The niche similarity of the two populations was significantly low (Schoener’s D = 0.093, P &lt; 0.005), suggesting the occurrence of a niche shift. The envelop and center of the realized climatic niche in China has shifted to lower temperature and less precipitation compared to that in its native range. The majority of invaded areas in southern China are in the stabilizing zone, whereas the colonization and adaptation zones are predicted to be at the leading edge of G. quadriradiata invasion in northern China. This suggests that the regional distribution of G. quadriradiata may be in a quasi-equilibrium state, and that the species continues to invade environmentally suitable areas. Alterations in G. quadriradiata’s niche would help to explain why this species is so invasive in China.
Transit origami: a method to coherently fold exomoon transits in time series photometry
Authors: Kipping David 
Published: July 2021

ABSTRACT
One of the simplest ways to identify an exoplanetary transit is to phase fold a photometric time series upon a trial period – leading to a coherent stack when using the correct value. Such phase-folded transits have become a standard data visualization in modern transit discovery papers. There is no analogous folding mechanism for exomoons, which would have to represent some kind of double fold: once for the planet and then another for the moon. Folding with the planet term only, a moon imparts a small decrease in the surrounding out-of-transit averaged intensity, but its incoherent nature makes it far less convincing than the crisp stacks familiar to exoplanet hunters. Here, a new approach is introduced that can be used to achieve the transit origami needed to double fold an exomoon, in the case where a planet exhibits transit timing variations (TTVs). This double fold has just one unknown parameter, the satellite-to-planet mass ratio, and thus a simple one-dimensional grid search can be used to rapidly identify power associated with candidate exomoons. The technique is demonstrated on simulated light curves, exploring the breakdown limits of close-in and/or inclined satellites. As an example, the method is deployed on Kepler-973b, a warm mini-Neptune exhibiting an 8-min TTV, where the possibility that the TTVs are caused by a single exomoon is broadly excluded, with upper limits probing down to a Ganymede-sized moon.
Intraday multiband optical variability of BL Lacertae object S5 0716+714
Authors: Dai Yan , Fang Yue , Zhang Xiaoyuan , Meng Nankun , Wu Jianghua , Zhu Zong-Hong 
Published: July 2021

ABSTRACT
We monitored the BL Lac object S5 0716+714 in four optical wavebands with four telescopes on 11 nights from 2012 to 2017. The object was active during most of those nights. It was brightest on 2012 November 7 with 11.720 mag in the I band and reached the faintest state on 2016 January 22 with 15.770 mag in the R band corresponding to ∼15.230 mag in the I band. Intraday variations in all bands were found on 6 d, while in partial bands on 3 d. Strong bluer-when-brighter chromatism was observed on 8 nights. Correlation analyses revealed interband time delays from 4 to 40 min in the intraday variability on 5 nights. Both hard and soft lags were observed in this object, indicating complicated emission process in the jet. The analysis on the interband time delays indicated that the radiative cooling may dominate the optical time lags in S5 0716+714 occasionally, but cannot be invoked as the sole explanation.
Inferring the concentration of dark matter subhaloes perturbing strongly lensed images
Authors: Minor Quinn , Kaplinghat Manoj , Chan Tony H , Simon Emily 
Published: July 2021

ABSTRACT
We demonstrate that the perturbations of strongly lensed images by low-mass dark matter subhaloes are significantly impacted by the concentration of the perturbing subhalo. For subhalo concentrations expected in Lambda cold dark matter (ΛCDM), significant constraints on the concentration can be obtained at Hubble Space Telescope (HST) resolution for subhaloes with masses larger than about $10^{10}\, {\rm M}_\odot$. Constraints are also possible for lower mass subhaloes, if their concentrations are higher than the expected scatter in CDM. We also find that the concentration of lower mass perturbers down to $\sim 10^8\, {\rm M}_\odot$ can be well constrained with a resolution of ∼0.01 arcsec, which is achievable with long-baseline interferometry. Subhalo concentration also plays a critical role in the detectability of a perturbation, such that only high-concentration perturbers with mass $\lesssim 10^9\, {\rm M}_\odot$ are likely to be detected at HST resolution. If scatter in the ΛCDM mass–concentration relation is not accounted for during lens modelling, the inferred subhalo mass can be biased by up to a factor of 3 (6) for subhaloes of mass $10^9 \, {\rm M}_\odot \,(10^{10} \, {\rm M}_\odot$); this bias can be eliminated if one varies both mass and concentration during lens fitting. Alternatively, one may robustly infer the projected mass within the subhalo’s perturbation radius, defined by its distance to the critical curve of the lens being perturbed. With a sufficient number of detections, these strategies will make it possible to constrain the halo mass–concentration relation at low masses in addition to the mass function, offering a probe of dark matter physics as well as the small-scale primordial power spectrum.
Behavioural responses of Intensivists to stressors in Intensive Care
Authors: Dennis D , van Heerden P V , Khanna R , Knott C I 
Published: July 2021

Abstract

Background
The hospital intensive care unit (ICU) environment encompasses sick patients who present for care in health crisis. Healthcare in this setting is complex, often involving the co-ordination of multiple professional teams, all under significant time pressures. The sequelae for staff interacting in this dynamic and often volatile setting are variable, depending upon their coping skillset and their familiarity with the stressors.

Aims
The primary aim of this study was to describe and in doing so, normalize the behavioural responses expressed by ICU doctors (Intensivists) in response to stressful workplace events. The secondary aim was to identify those responses that contributed to resilience.

Methods
A prospective qualitative study of senior Intensivists using a semi-scripted iterative interview. Data were transcribed and thematically analysed with verbatim quotations selected to support coding choices.

Results
Nineteen experienced Intensivists from three sites in Australia and Israel participated. Clinicians described conscious, physiological and professional responses to stressors, including sense-making and taking time to process information with appropriate support. Two of the most important mitigation processes revealed were the use of reflective learning and preventative practice changes to prevent future errors. These were overlaid with the importance of disclosure and transparency in clinical work.

Conclusions
Repeated exposure to stressful events potentiates burnout, wherein staff no longer experience satisfaction and enjoyment in what they do. This paper presents the behavioural responses that experienced Intensivists described in relation to stressful events in the ICU, including steps taken to mitigate the effects of these events on their personal well-being.
Increased Capsule Thickness and Hypermotility Are Traits of Carbapenem-Resistant Acinetobacter baumannii ST3 Strains Causing Fulminant Infection
Authors: Rakovitsky Nadya , Lellouche Jonathan , Ben David Debby , Frenk Sammy , Elmalih Polet , Weber Gabriel , Kon Hadas , Schwartz David , Wolfhart Liat , Temkin Elizabeth , Carmeli Yehuda 
Published: July 2021

Abstract

Background
Acinetobacter baumannii is a successful nosocomial pathogen, causing severe, life-threatening infections in hospitalized patients, including pneumonia and bloodstream infections. The spread of carbapenem-resistant Acinetobacter baumannii (CRAB) strains is a major health threat worldwide. The successful spread of CRAB is mostly due to its highly plastic genome. Although some virulence factors associated with CRAB have been uncovered, many mechanisms contributing to its success are not fully understood.

Methods
Here we describe strains of CRAB that were isolated from fulminant cases in 2 hospitals in Israel. These isolates show a rare hypermucoid (HM) phenotype and were investigated using phenotypic assays, comparative genomics, and an in vivo Galleria mellonella model.

Results
The 3 isolates belonged to the ST3 international clonal type and were closely related to each other, as shown by Fourier-transform infrared spectroscopy and phylogenetic analyses. These isolates possessed thickened capsules and a dense filamentous extracellular polysaccharides matrix as shown by transmission electron microscopy (TEM), and overexpressed the capsule polysaccharide synthesis pathway-related wzc gene.

Conclusions
The HM isolates possessed a unique combination of virulence genes involved in iron metabolism, protein secretion, adherence, and membrane glycosylation. HM strains were more virulent than control strains in 2 G. mellonella infection models. In conclusion, our findings demonstrated several virulence factors, all present in 3 CRAB isolates with rare hypermucoid phenotypes.
Effects of Gender-Affirming Hormone Therapy on Progression Along the HIV Care Continuum in Transgender Women
Authors: Summers Nathan A , Huynh Trang T , Dunn Ruth C , Cross Sara L , Fuchs Christian J 
Published: July 2021

Abstract

Background
Progression along the HIV care continuum has been a key focus for improving outcomes for people with HIV (PWH). Transgender women with HIV (TGWWH) have not made the same progress as their cisgender counterparts.

Methods
All PWH identifying as transgender women receiving care at our clinic from 1/1/2015 to 12/31/2019 were identified from the electronic health records (EHRs) using International Classification of Diseases (ICD) codes. Demographics, laboratory data, prescription of gender-affirming hormone therapy (GAHT), and visit history were abstracted from the EHR. Retention in care and viral suppression were defined using Centers for Disease Control and Prevention definitions. The proportions of TGWWH who were consistently retained in care or virally suppressed over time were calculated using a binary response generalized mixed model including random effects and correlated errors.

Results
Of the 76 PWH identified by ICD codes, 2 were excluded for identifying as cisgender and 15 for insufficient records, leaving 59 TGWWH included for analysis. Patients were on average 35 years old and Black (86%), with a median CD4 count of 464 cells/µL. There were 13 patients on GAHT at study entry and 31 receiving GAHT at any point during the study period. Fifty-five percent were virally suppressed at study entry and 86% at GAHT initiation. The proportion of TGWWH who were consistently virally suppressed over time was greater among those receiving GAHT compared with those who were not (P = .04).

Conclusions
Rates of viral suppression were significantly greater among TGWWH receiving GAHT when compared with those who were not. More research to evaluate the reasons behind this effect is needed.
Clostridioides difficilePrevalence in the United States: National Inpatient Sample, 2016 to 2018
Authors: Petersen Molly R , Cosgrove Sara E , Klein Eili Y , Zhu Xianming , Quinn Thomas C , Patel Eshan U , Grabowski M Kate , Tobian Aaron A R 
Published: July 2021

AbstractData from the National Inpatient Sample indicate that Clostridioides difficile prevalence decreased from 10.1 (95% confidence interval [CI] = 9.9–10.3) to 8.6 (95% CI = 8.5–8.8) per 1000 hospital discharges between 2016 and 2018, after accounting for age, sex, and race. There was heterogeneity in the prevalence and decrease in prevalence by geographic region in the United States.
Desiccation and rehydration dynamics in the epiphytic resurrection fern Pleopeltis polypodioides
Authors: Prats Kyra A , Brodersen Craig R 
Published: July 2021

Abstract
The epiphytic resurrection—or desiccation-tolerant (DT)—fern Pleopeltis polypodioides can survive extreme desiccation and recover physiological activity within hours of rehydration. Yet, how epiphytic DT ferns coordinate between deterioration and recovery of their hydraulic and photosynthetic systems remains poorly understood. We examined the functional status of the leaf vascular system, chlorophyll fluorescence, and photosynthetic rate during desiccation and rehydration of P. polypodioides. Xylem tracheids in the stipe embolized within 3–4 h during dehydration. When the leaf and rhizome received water, tracheids refilled after ∼24 h, which occurred along with dramatic structural changes in the stele. Photosynthetic rate and chlorophyll fluorescence recovered to predesiccation values within 12 h of rehydration, regardless of whether fronds were connected to their rhizome. Our data show that the epiphytic DT fern P. polypodioides can utilize foliar water uptake to rehydrate the leaf mesophyll and recover photosynthesis despite a broken hydraulic connection to the rhizome.
Backreaction of mass and angular momentum accretion on black holes: General formulation of metric perturbations and application to the Blandford–Znajek process
Authors: Kimura Masashi , Harada Tomohiro , Naruko Atsushi , Toma Kenji 
Published: July 2021

Abstract
We study the metric backreaction of mass and angular momentum accretion on black holes. We first develop the formalism of monopole and dipole linear gravitational perturbations around Schwarzschild black holes in Eddington–Finkelstein coordinates against generic time-dependent matter. We derive the relation between the time dependence of the mass and angular momentum of the black hole and the energy–momentum tensors of accreting matter. As a concrete example, we apply our formalism to the Blandford–Znajek process around slowly rotating black holes. We find that the time dependence of the monopole and dipole perturbations can be interpreted as a slowly rotating Kerr metric with time-dependent mass and spin parameters, which are determined from the energy and angular momentum extraction rates of the Blandford–Znajek process. We also show that the Komar angular momentum and the area of the apparent horizon are decreasing and increasing in time, respectively, while they are consistent with the Blandford–Znajek argument of energy extraction in terms of black hole mechanics if we regard the time-dependent mass parameter as the energy of the black hole.