bluuebunny/crossref_metadata_2025_split huggingface dataset:
How do I implement pathogen‐reduced platelets?
Authors: Pham Tho D. , Kadi Wendy , Shu Elaine , Pandey Suchitra , Sussmann Harry , Shan Hua , Virk Mrigender S. 
Published: November 2021

AbstractBackgroundSeveral risk mitigation steps have improved the safety of platelets in regard to bacterial contamination, but this continues to be a concern today. A Food and Drug Administration (FDA) Guidance issued in December 2018 aims to further limit this risk. The guidance offers multiple pathways for compliance, and hospital blood banks will have to collaborate with blood donor centers to assess various factors before deciding which method is most appropriate for them.Methods and materialsOur institution considered several factors before moving forward with pathogen reduction technology. This included an assessment of platelet shelf‐life, bacterial testing requirements, the efficacy of low‐yield platelets, and managing a mixed platelet inventory. The decision to transition to pathogen‐reduced platelets was associated with complex collection and processing limitations that resulted in either an increase in platelets that were over‐concentrated or products with a low platelet yield.ResultsThrough trials of various collection settings with unique target volumes and target platelet yields, our blood donor center was able to optimize the production. At the hospital end, this transition required a thorough review of low‐yield platelet products and their clinical efficacy. Additionally, this implementation necessitated collaboration with clinical colleagues, comprehensive education, and training.ConclusionsPathogen‐reduced platelets would be the most efficient way for our institution to be compliant. This summary may serve as a roadmap for other institutions that are considering which FDA prescribed method to use and provide support for those that have decided on pathogen reduction technology but need to optimize their collections to best utilize low‐yield products.
Reported outcomes and characteristics of objective structured clinical examinations in advanced practice nursing education: a scoping review protocol
Authors: Strobehn Patricia K. , Zabriskie Denise , Chung Catherine E. , Mazzia Faye , Mecham Kelly 
Published: November 2021

ABSTRACT

Objective:
The objective of this scoping review is to identify the outcomes reported from objective structured clinical examinations in advanced practice registered nurse education and to describe their characteristics.

Introduction:
Graduate medical education has used objective structured clinical examinations to assess student health professionals since 1975. Nursing programs have adopted objective structured clinical examinations to assess evidence-based practice and clinical competency of advance practice nursing students, but little is known about the outcomes that are being reported.

Inclusion criteria:
This review will consider evidence on the outcomes and other characteristics of objective structured clinical examinations for students enrolled in graduate-level advanced practice nurse education programs (ie, nurse practitioners, clinical nurse specialists, nurse midwives, and nurse anesthetists). All types of evidence will be considered, including quantitative and qualitative studies, systematic reviews, as well as text and opinion papers.

Methods:
This review will be conducted in accordance with the JBI methodology for scoping reviews. A literature search will be conducted in PubMed, CINAHL, MEDLINE, Nursing and Allied Health, Scopus, and Google Scholar. Sources that are published in English or that could be translated into English will be considered for inclusion. No date limit will be applied. Study selection and data extraction will be conducted by three independent reviewers. Any disagreements will be resolved through discussion. The scoping review findings will be presented in a narrative style and reported using diagrams and extraction tables.
Management of spinal cord injury–related pain using complementary and alternative medicine: a scoping review protocol
Authors: Mashola Mokgadi Kholofelo , Ajidahun Adedayo Tunde , Korkie Elzette , Mothabeng Diphale Joyce 
Published: November 2021

ABSTRACT

Objective:
This scoping review will identify complementary and alternative medicine methods used to manage spinal cord injury–related pain.

Introduction:
Spinal cord injury–related pain is common, with a third of individuals experiencing severe pain. Conventional interventions are well documented, however, pain relief remains elusive for people with spinal cord injuries. Although complementary and alternative medicine is available to alleviate various health problems, little is known about the complementary and alternative medicine methods used to manage pain in people with spinal cord injuries.

Inclusion criteria:
This review will consider all studies on complementary and alternative medicine treatment methods used by adults with spinal cord injury to treat their associated pain. The concept of interest in this study is complementary and alternative medicine. Quantitative, qualitative, and mixed methods studies, text and opinion papers, as well as systematic reviews will be included in this review.

Methods:
A three-step search strategy, consisting of an initial limited search, a full search, and a screening of the reference lists of all included articles will be undertaken. Key information sources to be searched include CINAHL, Cochrane Library, JBI Evidence Synthesis, MEDLINE, Scopus, Web of Science, DynaMed, Natural Medicines, HerbMed, Open Dissertations, and OpenGrey. All titles and abstracts of identified citations will be screened and then uploaded to a reference management program. The full text of studies potentially meeting the inclusion criteria will be assessed in detail, and relevant data will be extracted and reported in tabular format, in line with the objectives and scope of the review.
Development of a Low-Cost Exhaust H2 Measurement Method for In-Use Vehicles
Authors: Guan Mark , Kirchen Patrick , Rogak Steven , Steiche Patrick 
Published: November 2021

Abstract
Port-injected hydrogen (H2) can be used as a partial substitution of diesel fuel in compression-ignition engines to reduce GHG emissions. For port-injected H2 systems, incomplete combustion or valve overlap can result in H2 slip, which increases the brake-specific fuel consumption. In this study, a low-cost method is developed to measure the H2 slip in the exhaust of a heavy-duty truck under real-world operating conditions. The truck is equipped with a 2016 15L Detroit diesel engine converted to run in dual-fuel mode with port-injected H2 ignited by directly injected diesel.
Existing H2 detecting methods used for steady-state laboratory tests either have slow response time or require well-controlled testing environments. To develop a method suitable for transient on-road H2 measurements, we utilized a low-cost semiconductor sensor. The output of the sensor is potentially influenced by temperature, relative humidity (RH), gas flow rate, as well as the sensor’s resistance in the ambient air (R0) and the pre-heating strategy. Firstly, the characteristics of R0 was investigated in controlled benchtop tests, where pre-heating time, gas temperature, and RH were monitored. Then, the sensor was calibrated using a standard gas mixture of H2 and nitrogen. Finally, a Portable Emission Measurement System (PEMS) was developed to control the conditions of the sample gas. The sensor output was recorded using a low-cost Raspberry Pi Data Acquisition (DAQ) system in combination with an analog HAT (Hardware attached on top) module at a frequency of 4Hz.
The results from the benchtop tests show that RH and flow rate both have significant influences on the sensor’s output. To ensure a stable R0, thirty minutes of pre-heating time is required. After calibration, the sensor’s readings are within 15% difference compared with the actual values. Data from the on-road tests demonstrated the applicability of the system for in-use vehicle’s exhaust H2 measurement. It was found from this data that the sensor’s average response time to rising H2 concentrations is 4.5s, but that the response to decreasing concentrations is much slower. The exhaust H2 concentrations, together with the engine operating data, were used to generate H2 emission maps, which provide insight into the relationship between the engine load, engine speed and the H2 slip. With further sensor development and sample gas control, this method can achieve high accuracy and extended application in in-use vehicle’s H2 emission measurements.
Compression Rubber Damper Assessment Through Simulation
Authors: Biyani Mayur , Mittal Jugal , Sharma Pranay , Parekar Vinod 
Published: November 2021

Abstract
Rubber torsional vibration dampers are often used on mid-range engines. Usually, the geometry of a rubber torsional vibration damper is such that the rubber element in it undergoes shear.
However, in the work presented, a compression rubber damper is being proposed, in which the rubber element undergoes compression rather than shear. The proposed compression rubber damper, just like the shear rubber damper, is a tuned damper.
An analytical tool is being used to evaluate the stiffness of compression rubber design and thus evaluate its performance. The rubber geometry, material and plate design are selected through simulations.
The analytical tool demonstrates the functionality of the compression rubber damper paper and focuses on simulation-based product development using ANSYS for FEA and an in-house tool for torsional vibration analysis.
Prediction of Exhaust System Vibration Through Harmonic Analysis & High Cycle Fatigue Life Evaluation
Authors: Saikia Bhaskarjyoti , Kulkarni Girish , Sathe Hrushikesh , Kakde Pravin , Vyas Tanmay , Li Yiran 
Published: November 2021

Abstract
Exhaust system typically experiences vibration during engine operating conditions due to periodic disturbing forces (firing force and inertia force) which are generated from the engine. Natural frequency of the exhaust system gets excited due to the periodic forces causing resonance which often leads to high cycle fatigue (HCF) failure. Turbocharger is a part of exhaust system and it is mounted on the exhaust manifold. The periodic forces are transferred from engine base (Cylinder head and Block) and these forces gets amplified to overhanging components like exhaust system turbocharger. It is an industrywide practice to perform modal analysis to determine the natural frequencies of the system. However, modal analysis cannot predict the intensity with which the system would vibrate. Thus, we need to make some assumptions about the system vibration ‘g’ levels. Based on accuracy of this assumption, we may end up under-designing or over-designing the system. Harmonic analysis enables us to accurately predict the ‘g’ level at turbocharger using experimental cylinder head base excitations. After recording the correlation with experimental data in many cases it was found that this approach further aided in establishing damping constant factor of the exhaust manifold at elevated temperature.
This analysis process has been validated with multiple cases as it has turned out to be a potential approach while doing design risk assessments and optimizing the engine vibration validation efforts. The benefit of prediction of exhaust system vibration level allows us to avoid iterative design process in the early stage of product development thus optimizing the design by taking advantage of shifting the natural frequency of exhaust system to lower source excitation (cylinder head). This saves vast amount of simulation lead time. Another benefit of this process is that the prediction of resonance condition of exhaust system through simulation helps us to estimate the fatigue life against the predicted ‘g’ level.
Demonstration of the Benefits of SAE 30 Stationary Gas Engine Oil in Full Scale Engine Tests
Authors: Schasfoort Thijs , Fard Zoe , Gehrmann Torsten , Hollatz Steffen 
Published: November 2021

Abstract
This paper evaluates the benefits of an SAE 30 monograde stationary gas engine oil (SGEO) in comparison with SAE 40 monograde SGEOs with the focus on two main areas. First, to demonstrate and quantify the positive impact of lower viscosity on the fuel consumption rate, and second to demonstrate the faster lubrication of hard to reach points in the engine during startup. The current industry recognized fuel efficiency test methods for passenger car and on-road diesel engine sectors are not suitable for evaluating the fuel efficiency performance of a gas engine oil because of the significant differences in fuel type, engine operating conditions, and oil formulations. This paper, therefore, describes comparative studies of three different gas engine oils in a modern MAN E3262 E302 gas engine that was carefully adapted and fully instrumented. The performance of each oil with respect to fuel efficiency was assessed in an extensive program comprising endurance testing, stationary tests on various load/speed points and dynamic tests running the engine fired as well as non-fired (motored).
Another part of the test program explores the lubrication of hard to reach points in the engine, e.g. valve guide. The paper describes how the SAE 30 monograde oil results in faster lubrication of these parts during startup in comparison with the SAE 40 oils.
Characterization of a Lightly Loaded Underfloor Catalyzed Gasoline Particulate Filter in a Turbocharged Light Duty Truck
Authors: Bohac Stanislav V. , Ludlam Scott 
Published: November 2021

Abstract
A test program to characterize the benefits and challenges of applying a European series production catalyzed gasoline particulate filter (GPF) to a U.S. Tier 2 turbocharged light duty truck (3.5L Ecoboost Ford F150) in the underfloor location was initiated at the U.S. Environmental Protection Agency. The turbos and underfloor location keep the GPF relatively cool and minimize passive regeneration relative to other configurations. This study characterizes the relatively cool GPF in a lightly loaded state, approximately 0.1 to 0.4 g/L of soot loading, using four test cycles: 60 mph steady state, 4-phase FTP, HWFET, and US06. Measurements include GPF temperature, soot loading, GPF pressure drop, brake thermal efficiency (BTE), CO2, PM mass, elemental carbon (EC), filter-collected organic carbon (OC), CO, THC, and NOx emissions.
The lightly loaded underfloor GPF achieves 85–99% reduction in PM mass, 98.5–100.0% reduction in EC, and 65–91% reduction in filter-collected OC, depending on test cycle. The smallest reductions in PM and EC occur in the US06 cycle due to mild GPF regeneration caused by GPF inlet temperature exceeding 500°C. EC dominates filter-collected OC without a GPF, while OC dominates EC with a GPF. Composite cycle CO, THC, and NOx emissions are reduced by the washcoat on the GPF but the low temperature location of the GPF does not make best use of the catalyzed washcoat. Cycle average pressure drop across the GPF ranged from 1.25 kPa in the 4-phase FTP to 4.64 kPa in the US06 but did not affect BTE or CO2 emissions in a measurable way in any test cycle.
Comparison of Spray Formation of a Multi and a Single Hole Gasoline Direct Injector
Authors: Maliha Malki , Kubach Heiko , Koch T. 
Published: November 2021

Abstract
Direct injection in internal combustion engines is often realized with a multi hole injector which forms a spray pattern consisting of multiple jets with a small distance between their origin. This leads to an interaction of adjacent spray jets. The spray characteristic is significantly influenced by this interaction, and can considerably change the fuel evaporation and with it the emission behavior with varying number of holes or hole nozzle geometry [8]. Experimental investigations, especially if a good optical access to a single jet is necessary, often needs to use a comparable injector with a reduced number of holes. In addition to that, 3D-CFD simulation models can also use a reduction of spray jet number for a partial consideration of fuel mixture to reduce the computing time. For these cases a determination of the correlation between spray formation and reduced nozzle holes is important. In this work the spray patterns of an original 6-hole gasoline DI-injector and, after closing of 5 holes, the resulting 1-hole injector were compared. The fuel mass flow through one hole can change due to a change of hydrodynamic effects inside the nozzle and leads to a correcting factor for the injecting time, to get comparable fuel mass flows. The penetration depth, droplet speed, size and spatial distribution were measured. Additional investigations of the influence of the fuel pressure and fuel temperature were carried out.
Impact of Fuel Injection Pressure on Spray and Combustion Characteristics of OME and Diesel Blends
Authors: LeBlanc Simon , Yu Xiao , Pisciotto Gared , Han Xiaoye , Tjong Jimi , Zheng Ming 
Published: November 2021

Abstract
Emission regulations focus on the simultaneous reduction of NOx and particulate matter emissions, especially for heavy-duty engines. Oxygenated fuels offer significant advantages in reducing particulate emissions while having little effect on NOx emissions. In addition, renewable fuels present a GHG emission advantage to meet the zero-emission requirements of future hydrocarbon fuels. Among the leading contenders, oxymethylene dimethyl ether (OME) fuels have the potential to be used for direct injection applications. OME as a blend with diesel fuel offers a direct means of improving the emissions of current on-road diesel engines without modification.
In this paper, an empirical investigation into spray behavior and engine performance of diesel/OME fuel at 10% by mass has been performed under various fuel injection pressures. Neat diesel fuel was tested as a baseline case. The results are compared to tests under matching conditions using a diesel and OME fuel blend with a focus on spray characteristics, combustion behavior, and engine-out emissions. The physical properties of OME improve the volatility of diesel fuel and can tolerate shorter mixing times without promoting PM production. The PM emissions were found to be reduced by up to 50% and the combustion efficiency was improved at matching NOx levels with OME blending.
Ignition Stability Improvement and Emission Reduction via Multiple Ignition Sites Strategy Under Cold Start and Transient Conditions
Authors: Zhang Xiaoxi , Yu Xiao , Leblanc Simon , Zheng Ming , Tjong Jimi 
Published: November 2021

Abstract
Downsizing, turbocharging, and lean burn strategies offer improved fuel efficiency and engine-out emissions to that of conventional spark ignition engines. However, maintaining engine stability becomes difficult, especially at low load and low speed operation such as cold start conditions. Under cold start operation, the spark timing is retarded to rush catalyst warm-up temperature followed by advancing the spark timing for engine stability. In this sequence, securing ignition while using retarded spark timing is difficult because of the cold cylinder walls and low engine loads. Through previous investigations, the noval multiple ignition sites strategy demonstrated its capability to expend lean burn boundaries beyond traditional single core spark plug and improve cycle to cycle variation. In this work, multisite ignition is tested on a production 4-cylinder direct injection spark ignition engine.
A large number of tests are performed on the engine to investigate the impact of ignition strategy on emissions and stability during catalytic converter warm up period as part of the cold-start operation. Results show that the three-core spark igniter shortens the ignition delay thus providing a wider stable spark timing window for stable engine operation. As a result, the concentration of unburnt fuel in the exhaust gas can be reduced before the catalyst reaches the light-off temperature.
Multiphysics Modeling of Spark Discharges in High Crossflow Ignition Environments
Authors: Subramaniam Vivek , Raj Naveen , Karpatne Anand , Breden Douglas , Raja Laxminarayan 
Published: November 2021

Abstract
In SI engines, the initial stages of flame kernel formation play an important role in determining the overall thermal efficiency and in reducing the cycle-to-cycle variability. Introducing a cross-flow within the spark gap has shown to reduce the combustion fluctuations by shortening this initial ignition period and activating a larger volume of the fuel-air mixture. This work presents a computational study of spark discharges in high cross-flow ignition environments using a high-fidelity, multi-physics equilibrium plasma solver. The numerical framework is designed to simultaneously model chemically reacting fluid flow coupled with electromagnetics, surface ablation physics and external circuit dynamics in a fully coupled manner. The spark channel is simulated in a constant volume combustion chamber under different operating conditions and cross flow velocities. The simulation model is validated by comparing several key parameters associated with the discharge such as the breakdown voltage, dwell current, restrike timing, and spark stretch against experimental measurements.
Influence of Elevated Fuel Temperatures on the Spray Characteristics of Gasoline - Ethanol Blends
Authors: Miganakallu Niranjan , Purushothaman Ashwin Karthik , Atkinson William R. , Peters Nathan , Amaral Tadeu Miguel Malago , Leite Antonio Galdino , Yoshino Fernando Jun , Bunce Michael , Ra Youngchul , Naber Jeffrey D. 
Published: November 2021

Abstract
In this study, the effect of elevated fuel temperatures on the spray characteristics of gasoline-ethanol blends were studied in an optically accessible constant volume spray and combustion vessel. MAHLE SmartHeat® is a fuel heater located directly upstream of the fuel injector. High speed images of the spray injected from a six-hole gasoline direct injection injector typical of a side-injection engine were captured with shadowgraph imaging technique. Two fuel blends, gasoline with 10% ethanol (E10) and 85% ethanol (E85) were investigated at ambient conditions of 1 bar, 45°C and 4 bar, 180°C respectively at an injection pressure of 100 bar. Fuel temperatures were varied from 75 to 250°C. A comparison of the near nozzle and the global spray characteristics was made for the two fuels at those temperatures.
Results showed that flash boiling leads to two primary effects for the two fuel blends: (i) an appreciable increase in spray angle near the exit of the nozzle followed by (ii) a decrease in spray angle downstream of the nozzle due to the interaction of the plumes and the collapsing of the spray. Furthermore, for both fuel blends, upon flash boiling, entrainment and mixing were reduced downstream of the nozzle because of the collapse of the spray. To reduce this effect, nozzle orientations and geometries should be modified.
Scattering and absorption cross sections of Schwarzschild–anti-de Sitter black hole with quintessence
Authors: Ramírez Valeria , López L.A. , Pedraza Omar , Ceron V.E. 
Published: November 2021

In this paper, we study the scattering and absorption cross sections of a Schwarzschild–anti-de Sitter black hole surrounded by quintessence. The critical values of the cosmological constant and the normalization factor are obtained. We describe the event horizons and the extremal condition of the black hole surrounded by quintessence. The effects of quintessence on the classical and semi-classical scattering cross sections have been estimated. Additionally, the absorption cross section is studied with the sinc approximation in the eikonal limit. We consider the quintessence state parameter in the particular cases ω = –2/3 and –1/2.