bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of mathematical models of energy conversion processes in an induction motor supplied from an autonomous induction generator with parametric non-symmetry
Authors: Chenchevoi Volodymyr , Kuznetsov Valeriy , Kuznetsov Vitaliy , Chencheva Olga , Zachepa Iurii , Chornyi Oleksii , Kovzel Maksim , Kovalenko Viktor , Babyak Mykola , Levchenko Serhii 
Published: September 2021

The paper presents studies of the system "induction generator-induction motor" with parametric asymmetry on a mathematical model to determine the quality of generated electricity in load operating modes. A mathematical model of the "induction generator-induction motor" system has been developed taking into account losses in steel and parametric asymmetry. The analysis of the transient characteristics of an induction generator when a motor load is connected in symmetrical and asymmetrical modes of operation is carried out. The results of changes in the main characteristics of an induction motor at various degrees of parametric asymmetry in the generator are presented. The quality of the generated electricity was analyzed based on the calculations of the unbalance coefficients for each of the operating modes. The assessment of the thermal state in steady-state conditions was carried out using an equivalent thermal equivalent circuit. Thermal transients were investigated when starting an induction motor from an autonomous energy source based on an induction generator. On a thermal mathematical model, the study of the effect of the output voltage asymmetry on the heating of the connected induction motor was carried out. It is shown that the asymmetry of the output voltage of an induction generator reaches 3–10 % and causes overheating of the windings in excess of the permissible values. A regression model has been developed for studying the operating conditions of an induction motor when powered by an induction generator with an asymmetry of the stator windings. The use of the obtained equations will make it possible to determine the most rational combination of factors affecting the heating of the stator windings of induction machines, in which they will not overheat above the maximum permissible temperature values of the corresponding insulation classes
Development of an algorithm for calculating stable solutions of the Saint-Venant equation using an upwind implicit difference scheme
Authors: Aloev Rakhmatillo , Berdyshev Abdumauvlen , Akbarova Aziza , Baishemirov Zharasbek 
Published: September 2021

The problem of numerical determination of Lyapunov-stable (exponential stability) solutions of the Saint-Venant equations system has remained open until now. The authors of this paper previously proposed an implicit upwind difference splitting scheme, but its practical applicability was not indicated there. In this paper, the problem is solved successfully, namely, an algorithm for calculating Lyapunov-stable solutions of the Saint-Venant equations system is developed and implemented using an upwind implicit difference splitting scheme on the example of the Big Almaty Canal (hereinafter BAC). As a result of the proposed algorithm application, it was established that:
1) we were able to perform a computational calculation of the numerical determination problem of the water level and velocity on a part of the BAC (10,000 meters) located in the Almaty region;
2) the numerical values of the water level height and horizontal velocity are consistent with the actual measurements of the parameters of the water flow in the BAC;
3) the proposed computational algorithm is stable;
4) the numerical stationary solution of the system of Saint-Venant equations on the example of the BAC is Lyapunov-stable (exponentially stable);
5) the obtained results (according to the BAC) show the efficiency of the developed algorithm based on an implicit upwind difference scheme according to the calculated time.
Since we managed to increase the values of the difference grid time step up to 0.8 for calculating the numerical solution according to the proposed implicit scheme.
Use of the transfer of the best european technologies to implement the system for forming of civil servant-leader
Authors: Podolchak Nazar , Tsygylyk Natalia , Khim Mariia 
Published: September 2021

Public service is a means to ensure interaction between the state and society. The well-being of the population directly depends on its effective functioning. As you know, the effectiveness of solving the tasks set is 80 % ensured by its leaders – civil servants-leaders. It is they who are the engine of positive changes and the guarantor of the effectiveness of the activities of the entire team. Therefore, in order to bring the civil service to a qualitatively new level of efficiency, it is necessary to change the approach to the formation of soft-skills and hard-skills of employees-leaders. For this, it is necessary to introduce a comprehensive system for the development of the necessary skills. It is worth, firstly, to apply the transfer of the best European technologies. Secondly, to take into account the realities of the post-industrial society. Thirdly, to take into account the opinion of the public. An example of the application of an integrated approach to the formation of an employee-leader is given. For this, an analysis of the system of training and advanced training of civil servants in a developing country, the leading countries of the European Union, the Organization for Economic Cooperation and Development – Germany, France, as well as the nearest country with positive experience of joining the EU – Poland. The skills and activities that contribute to the formation of a civil servant-leader both from the point of view of citizens and taking into account the competencies necessary for effective work are highlighted. For this, the methods of electronic sociological survey of public opinion between the ages of 18 and 60 were used in a sample of 1000 people with an average statistical dispersion of residence throughout the state and an analysis of literary sources. A system for the formation of an effective civil servant-leader with the use of technology transfer has been developed for implementation.
Sign language dactyl recognition based on machine learning algorithms
Authors: Kenshimov Chingiz , Buribayev Zholdas , Amirgaliyev Yedilkhan , Ataniyazova Aisulyu , Aitimov Askhat 
Published: September 2021

In the course of our research work, the American, Russian and Turkish sign languages were analyzed. The program of recognition of the Kazakh dactylic sign language with the use of machine learning methods is implemented. A dataset of 5000 images was formed for each gesture, gesture recognition algorithms were applied, such as Random Forest, Support Vector Machine, Extreme Gradient Boosting, while two data types were combined into one database, which caused a change in the architecture of the system as a whole. The quality of the algorithms was also evaluated.
The research work was carried out due to the fact that scientific work in the field of developing a system for recognizing the Kazakh language of sign dactyls is currently insufficient for a complete representation of the language. There are specific letters in the Kazakh language, because of the peculiarities of the spelling of the language, problems arise when developing recognition systems for the Kazakh sign language.
The results of the work showed that the Support Vector Machine and Extreme Gradient Boosting algorithms are superior in real-time performance, but the Random Forest algorithm has high recognition accuracy. As a result, the accuracy of the classification algorithms was 98.86 % for Random Forest, 98.68 % for Support Vector Machine and 98.54 % for Extreme Gradient Boosting. Also, the evaluation of the quality of the work of classical algorithms has high indicators.
The practical significance of this work lies in the fact that scientific research in the field of gesture recognition with the updated alphabet of the Kazakh language has not yet been conducted and the results of this work can be used by other researchers to conduct further research related to the recognition of the Kazakh dactyl sign language, as well as by researchers, engaged in the development of the international sign language
Development of green production technology and research of harpagophytum procumbens root dry extract
Authors: Kriukova Anna , Lytkin Dmytro , Marchenko Mykhailo , Vladymyrova Inna 
Published: September 2021

The aim of this work is to study of standardization parameters and pharmacological properties of Harpagophytum procumbens (H. procumbens) root dry extract.
Materials and methods – obtaining of H. procumbens root dry extract was performed in accordance with developed scheme that is characterized by simplicity and cost-effectiveness of technology compared to analogous scheme. Study of standardization parameters of obtained extract was performed in accordance with the requirements of the monograph «Harpagophyti extractum siccum» of the State Pharmacopoeia of Ukraine 2.2., harmonized with the monograph «Harpagophyti extractum siccum» of the European Pharmacopoeia 9.5. Pharmacology study of analgesic and anti-inflammatory activities were conducted on the rat paw formalin-induced edema model.
Results. Obtained H. procumbens root dry extract is a free flowing, non-hygroscopic, light brown powder with taste and odor that is specific to raw material of H. procumbens. Determined loss on drying was 3.2±0.18 %. Content of heavy metals in dry extract was not more than 0.01 % (100 ppm). Harpagoside was identified by TLC method. Chromatographic zones on the obtained chromatograms of the reference solution and test solutions are the same in intensity of a color, cross-over and sharpness of development. Based on the results of the research performed by HPLC method, it has been established that content of harpagoside in investigated H. procumbens root dry extract is 2.50±0.02 %.
According to the results of pharmacological research it was found that investigated dry extract (the content of harpagoside is not less than 37.0 mg/kg) showed a higher activity compared to reference drug («Phong Te Thap»).
Conclusions. A new method of obtaining dry extract of H. procumbens (3.5:1) was proposed. The developed green production technology is simple; it does not require special equipment and expensive solvents. A correspondence of quality parameters with the requirements of State Pharmacopoeia of Ukraine and European Pharmacopoeia: appearance, identification of harpagoside and fructose, loss of drying, content of heavy metals, assay of harpagoside (2.50±0.02 %) was set. Analgesic and anti-inflammatory activities of H. procumbens dry extract has been established
MicroRNA-23b-3p Deletion Induces an IgA Nephropathy-like Disease Associated with Dysregulated Mucosal IgA Synthesis
Authors: Li Hongzhi , Chen Zhichao , Chen Weitian , Li Jingyi , Liu Yunshuang , Ma Hongchuang , Shi Mingming , Sun Xuelian , Yao Xiusong , Li Zhijun , Pawluczyk Izabella Z.A , Zhang Shuchen , Barratt Jonathan , Lv Jicheng , Wang Kai , Zhao Binghai 
Published: September 2021

Significance Statement
Accumulating evidence implicates microRNAs in IgA nephropathy (IgAN), which is a common primary GN in which aberrant IgA aggregated with complement 3, with or without IgG/IgM is deposited in glomerular mesangium. We showed, in a mouse model, that miR-23b deficiency induced an IgA nephropathy-like disease, marked by mesangial IgA and C3 deposition, increased proteinuria, elevated serum IgA levels, and development of high blood pressure. Elevations in serum IgA levels and mesangial IgA deposition were associated with dysregulated mucosal IgA synthesis through targeting the activation-induced cytidine deaminase gene in the gut. miR-23b deficiency-induced dysfunctional kidney effects were likely mediated through regulation of expression of gremlin 2 (Grem2) and the transferrin receptor (Tfrc), which weexamined in human mesangial cells.

Background
IgA nephropathy (IgAN) is the most common primary GN worldwide. Circulating immune complexes form that are prone to deposition in the mesangium, where they trigger glomerular inflammation. A growing body of evidence suggests that dysregulated expression of microRNAs in IgAN may play a significant role in establishing the disease phenotype.

Methods
We generated single miR-23b-3p(miR-23b) knockout mice using CRISPR-Cas9.

Results
In humans, miR-23b levels are downregulated in kidney biopsies and sera of patients with IgAN, and serum miR-23b levels are negatively correlated with serum IgA1 levels. We show that miR-23b−/− mice develop an IgAN-like phenotype of mesangial IgA and C3 deposition associated with development of albuminuria, hypertension, an elevated serum creatinine, and dysregulated mucosal IgA synthesis. Dysregulation of IgA production is likely mediated by the loss of miR-23b–mediated suppression of activation-induced cytidine deaminase in mucosal B cells. In addition, we show that loss of miR-23b increases the susceptibility of the kidney to progressive fibrosis through loss of regulation of expression of gremlin 2 and IgA accumulation through downregulation of the transferrin receptor.

Conclusions
Our findings suggest an indispensable role for miR-23b in kidney disease, and in particular, IgAN. miR-23b may in the future offer a novel therapeutic target for the treatment of IgAN.
CHOP-ASO Ameliorates Glomerular and Tubular Damage on Top of ACE Inhibition in Diabetic Kidney Disease
Authors: Shahzad Khurrum , Fatima Sameen , Al-Dabet Moh’d Mohanad , Gadi Ihsan , Khawaja Hamzah , Ambreen Saira , Elwakiel Ahmed , Klöting Nora , Blüher Matthias , Nawroth Peter P. , Mertens Peter R. , Michel Sven , Jaschinski Frank , Klar Richard , Isermann Berend 
Published: September 2021

Significance Statement
The endoplasmic reticulum (ER) stress response and the maladaptive and cell-death–promoting transcription factor C/EBP homologous protein (CHOP) have been linked with diabetic kidney disease (DKD). Specific therapies targeting maladaptive ER stress signaling are lacking. We show that an antisense oligonucleotide (ASO)–based approach reducing CHOP expression ameliorates DKD in mice, providing renal protection on top of ACE inhibition. CHOP inhibition improves both glomerular and tubular damage. ASO-based therapies are a potentially new approach to target maladaptive ER stress signaling and improve DKD.

Background
Maladaptive endoplasmic reticulum stress signaling in diabetic kidney disease (DKD) is linked to increased glomerular and tubular expression of the cell-death–promoting transcription factor C/EBP homologous protein (CHOP). Here, we determined whether locked nucleic acid (LNA)–modified antisense oligonucleotides (ASOs) targeting CHOP ameliorate experimental DKD.

Methods
We determined the efficacy of CHOP-ASO in the early and late stages of experimental DKD (in 8- or 16-week-old db/db mice, respectively) alone or with an angiotensin-converting enzyme inhibitor (ACEi), after an in vivo dose-escalation study. We used renal functional parameters and morphologic analyses to assess the effect of CHOP-ASO and renal gene-expression profiling to identify differentially regulated genes and pathways. Several human CHOP-ASOs were tested in hyperglycemia-exposed human kidney cells.

Results
CHOP-ASOs efficiently reduced renal CHOP expression in diabetic mice and reduced markers of DKD at the early and late stages. Early combined intervention (CHOP-ASO and ACEi) efficiently prevented interstitial damage. At the later timepoint, the combined treatment reduced indices of both glomerular and tubular damage more efficiently than either intervention alone. CHOP-ASO affected a significantly larger number of genes and disease pathways, including reduced sodium-glucose transport protein 2 (Slc5a2) and PROM1 (CD133). Human CHOP-ASOs efficiently reduced glucose-induced CHOP and prevented death of human kidney cells in vitro.

Conclusions
The ASO-based approach efficiently reduced renal CHOP expression in a diabetic mouse model, providing an additional benefit to an ACEi, particularly at later timepoints. These studies demonstrate that ASO-based therapies efficiently reduce maladaptive CHOP expression and ameliorate experimental DKD.
The Use of Islamic Literature to Teach Ethical English
Authors: Irwansyah Dedi , Andianto Andianto , Madkur Ahmad 
Published: September 2021

Ethical English instruction has paved the way for every religion to make its interpretation. From the Islam religion perspective, such interpretation is still under research. This study describes how ethical English instruction takes place in an Indonesian Islamic higher education institution; how literature, particularly Islamic literature, becomes a factor of ethical English instruction; and the students' transformation through ethical English instruction. Applying a content analysis method, this case study involved 60 freshmen students of the English language education program of State Islamic Institute of Metro, Lampung, Indonesia. The research data was drawn from five main data sources, namely interviews, classroom observations, teaching materials, samples of students' works, and questionnaires. This study shows that (1) the use of Islamic literature to teach ethical English in the Indonesian Islamic higher education is potential; (2) text exploitability becomes a dominant factor in ethical English instruction; and (3) a contextualized approach, derived from the existing global approach and local teaching method, transforms the students positively. It is concluded that ethical English teaching within Indonesian Islamic higher education ought to utilize Islamic literature and be conducted through a contextualized approach.
A review of airflow rate estimation techniques for natural ventilation in buildings
Authors: Chen Austin Miguel , Mora Dafni , Bruneau Denis , Sempey Alain 
Published: September 2021

As natural ventilation involves local and global interactions, the estimation of these interactions can be performed by many approaches. Such approaches, rather more experimental and numerical than analytical, often require a great deal of instrumentation and equipment, which results in higher demands on project budget and funding. The present work is devoted to comprehending the natural ventilation concept, and to assess the existing experimental techniques already implemented for past researchers in the estimation of the ventilation airflow rate due to the wind and thermal buoyancy effects. A brief review of modeling techniques is also presented. This will provide a strong theoretical grasp of the natural ventilation process as part of the main elements in the thermal behavior of buildings. Ultimately, these bases are intended to help choose the most suitable techniques to estimate the natural ventilation airflow rate. The adequate benefit-to-budget technique appears to be the airtightness tests (blower door tests), since empirical Equations relating the airflow directly to the pressure difference in the building for both cases: infiltrations (openings closed) and openings opened, can be obtained. Also, the location of the leakages can be identified without complications, and this technique has the potential to estimate in situ the airflow capacity and friction characteristics of the openings.
Prevalence, Patterns, and Predictors of Yoga Practice Among Adults in an Urban Population in Eastern India
Authors: Mohanty Satyajit , Sahoo Jyotiranjan , Panigrahi Sandeep Kumar , Epari Venkatarao , Yasobant Sandul , Samantsinghar Pusparaj 
Published: September 2021

Abstract
The objective of this study was to determine the prevalence and predictors of yoga practice. This cross-sectional study was conducted as a part of a larger study that included yoga as a form of physical activity. Data were collected during April and August 2019 from the adult urban population of Bhubaneswar, India. This study was conducted using a cluster random sampling method. A representative sample (n = 1,203) of adults aged 18–59 years, irrespective of gender, was interviewed using a questionnaire adapted from the 2012 U.S. National Health Interview Survey, with the Epicollect5 handheld data-collection tool. Predictors of yoga practice were explored using multivariable logistic regression. The mean age of the participants was 35.19 ± 10.67 years, with 55.3% males. The majority were Hindu (93.62%) and belonged to the unre s e rved category (65.60%), people generally of higher relative socioeconomic status. The lifetime prevalence of yoga was 16.9%. Prevalence of any form of yoga (yoga, pranayama, or meditation), all forms of yoga (yoga, pranayama, and meditation), pranayama, and meditation was 17.0%, 10.7%, 14.3%, and 11.4%, respectively. After adjusting for confounders, female gender, Hindu religion, minimum of higher-secondary or graduate-level education, and having received advice from professionals for yoga practice had significantly higher odds of practicing yoga, and those of higher socioeconomic status had significantly lower odds of practicing yoga. We found a low prevalence of yoga. Sociodemographic characteristics like gender, religion, education, socioeconomic status, and other factors like learning yoga from professionals may be important predictors of continued yoga practice.
Slips of the Tongue by Jokowi and Prabowo in the Presidential Debates 2019
Authors: Qimmahtum Rohi , Cahyono Bambang Yudi , Kadarisman Achmad Effendi 
Published: September 2021

Abstract: This current research, using a descriptive qualitative method, aims to find out and analyze the types of slip of the tongue produced by Jokowi and Prabowo during the presidential debates 2019. This current research applied the theories proposed by Altiparmak and Koruoglu (2014) to analyze types of slip of the tongue. The data were taken from video of the 2nd round presidential debate 2019, obtained from YouTube. The collected data were then transcribed and analyzed based on the types of slip of the tongue proposed by Altiparmark and Koruoglu (2014). There were 100 utterances of data found of slip of the tongue produced by Jokowi and Prabowo during the 2nd round of presidential debate 2019. Jokowi produced 60 slips of the tongue: deletions (46.67%), blends (21.67%), substitutions (11.67%), anticipations (11.67%), additions (5%), perseverations (1.66%), and misdeviations (1.66%). Prabowo produced 40 slips of the tongue: deletions (26.83%), substitutions (26.83%), anticipations (21.95%), additions (19.51%), blends (2.44%), and misdeviations (2.44%). The type of perseverations of slip of the tongue occurred in Jokowi’s utterances but did not occur in Prabowo’s utterances. Whereas, shifts and exchanges slip of the tongue are the two types that did not occur in their utterances.
Keywords: slips of the tongue, Jokowi, Prabowo, presidential debates
Abstrak: Penelitian ini menggunakan metode deskriptif kualitatif yang bertujuan untuk mengetahui dan menganalisa tipe-tipe selip lidah yang dihasilkan oleh Jokowi dan Prabowo selama debat presiden 2019. Penelitian ini menggunakan teori yang diajukan oleh Altiparmak dan Koruoglu (2014) untuk menganalisis tipe-tipe selip lidah. Data diambil dari video ronde kedua debat presiden 2019 yang diperoleh dari YouTube. Data yang terkumpul kemudian ditranskripsikan dan dianalisis berdasarkan pada tipe-tipe selip lidah yang diajukan oleh Altiparmak and Koruoglu (2014). Terdapat 100 data ucapan selip lidah yang ditemukan yang dihasilkan oleh Jokowi dan Prabowo selama ronde kedua debat presiden 2019. Jokowi memproduksi 60 kali selip lidah: deletions (46.67%), blends (21.67%), substitutions (11.67%), anticipations (11.67%), additions (5%), perseverations (1.66%), dan misdeviations (1.66%). Prabowo memproduksi 40 kali selip lidah: deletions (26.83%), substitutions (26.83%), anticipations (21.95%), additions (19.51%), blends (2.44%), dan misdeviations (2.44%). Perseverations adalah tipe kilir lidah yang terjadi pada ujaran Jokowi namun tidak terjadi pada ujaran Prabowo. Sedangkan shifts dan exchanges merupakan tipe selip lidah yang tidak terjadi dalam ujaran mereka.
Kata kunci: selip lidah, Jokowi, Prabowo, debat pemilihan presiden