bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seizure Prediction in Genetic Rat Models of Absence Epilepsy: Improved Performance through Multiple-Site Cortico-Thalamic Recordings Combined with Machine Learning
Authors: Budde Björn , Maksimenko Vladimir , Sarink Kelvin , Seidenbecher Thomas , van Luijtelaar Gilles , Hahn Tim , Pape Hans-Christian , Lüttjohann Annika 
Published: November 2021

AbstractSeizure prediction is the grand challenge of epileptology. However, effort was devoted to prediction of focal seizures, while generalized seizures were regarded as stochastic events. Long-lasting local field potential (LFP) recordings containing several hundred generalized spike and wave discharges (SWDs), acquired at eight locations in the cortico-thalamic system of absence epileptic rats, were iteratively analyzed in all possible combinations of either two or three recording sites, by a wavelet-based algorithm, calculating the product of the wavelet-energy signaling increases in synchronicity. Sensitivity and false alarm rate of prediction were compared between various combinations, and wavelet spectra of true and false positive predictions were fed to a random forest machine learning algorithm to further differentiate between them. Wavelet analysis of intracortical and cortico-thalamic LFP traces showed a significantly smaller number of false alarms compared with intrathalamic combinations, while predictions based on recordings in Layers IV, V, and VI of the somatosensory-cortex significantly outreached all other combinations in terms of prediction sensitivity. In 24-h out-of-sample recordings of nine Genetic Absence Epilepsy Rats from Strasbourg (GAERS), containing diurnal fluctuations of SWD occurrence, classification of true and false positives by the trained random forest further reduced the false alarm rate by 71%, although at some trade-off between false alarms and sensitivity of prediction, as reflected in relatively low F1 score values. Results provide support for the cortical-focus theory of absence epilepsy and allow the conclusion that SWDs are predictable to some degree. The latter paves the way for the development of closed-loop SWD prediction-prevention systems. Suggestions for a possible translation to human data are outlined.
Developing water supply system in Szőgye
Authors: Fecser Nikolett , Lakatos István 
Published: November 2021

Abstract
The deteriorative processes occurring in the environment, the growth of population, the water demand of industry and agriculture, point out day after day the increasing role of water management. The economical use of drinking-water consumption as well as the cost reduction is becoming more and more important. In this research, the measure of a water supplier of Győr was examined in terms of implementing the purposes above.
Mesoscopic metastable liquid in congruent vapor-liquid diagram of argon from about zero up to boyle`s temperature (review of FT-model)
Authors: Rogankov V.B. , Shvets M.V. , Rogankov O,V, 
Published: November 2021

Such paradigms of the coupled classical metastability and nonclassical criticality as the existence of a unified EOS (common for both gas and liquid phases) with its mean-field (mf), so-called Andrews-van der Waals’ critical point (CP) should be questioned to recognize the realistic stratified structure of a mesoscopic liquid phase. It exists supposedly in the wide range of temperatures located between about zero , K and up to the singular first Boyle’s point . Its opposite, also singular second Boyle’s point corresponds to the alternative origin for the crossover continuous bounds separating the specific structural strata of a mesoscopic liquid. The region of a heterogeneous l-phase spanning the whole temperature range can be termed the non-Gibbsian phase (due to its discrete cluster-like structure) without any appeals to the concept of a spinodal decomposition. The respective metastable liquid stratum is formed by three segments of supercritical , subcritical and sublimation metastable states of a formally incompressible liquid constrained by the pair of fixed extensive parameters (N,V). Its location on the CVL-diagram is restricted by the new introduced here ml-bound and by the known Zeno-line (ZL) bound. Thus, all above-mentioned strata belong to the region of soft fluid with the dominance of interparticle attraction. The remaining parts of CVL-diagram are spanned either by the real gas state-points and solid state-points (crystalline and/or amorphous) or by the region of hard fluid in the classification proposed by Ben-Amotz and Herschbach.
THE THEORETICAL ANALYSIS OF THE INDIVIDUALTYPOLOGICAL PERSONAL FEATURES INFLUENCE ON THE ACTIVITY EFFICIENCY PROBLEM
Authors: Yelesina M. O. 
Published: November 2021

The article presents a theoretical look on the problem of the infusion of individual-typological features on the performance efficiency. It is reflected in science through some native and foreign scientific glances, so that they can be understood together. It is designated the main warehouse individual-typological features day and the efficiency of the activity inflow is given. The preliminaries relevance is amortized by the rapid pace development and life rhythm and the significant information technologies dynamism. It is the reason why people think of the human dignity of guilt of the species, mostly is very effective. The object of investigation is the interchange of individual-typological features and efficiency of professional performance. The subject of this work is an individual-typological specialty. The aim of the article is an analysis of current of native and foreign scientists’ works, directed to the efficiency specialties development. It is also the designation and storage of such individual-typological features as temperament, character and health, as well as the perspectives for the future. The environment is attributed to an understanding of an individual people’s style, who, behind their dynamic features, appeal to the individual temperament. The area of praxeology has been developed, as it has taken the openness of efficiency in other spheres of activity. The understanding of efficiency is seen as the main warehouse assessment of the professional performance success. It is presented the value of the efficiency and the complex characteristics of professional performance, which is rotated in the most significant indicators and determined by the integral people powers as a special feature. It is summarized that the effectiveness of the specialty in professional activity is rich, consequently it is determined by the individual-typological features variety appeared in temperament, character, health, and professionalism. The investigating perspective in this direction is to carry out an empirical research of the individual-typological features influence on the efficiency of performance.
THE CONCEPT OF COMBUSTION PROCESS ORGANISATION IN A BOXER TWO-STROKE DIESEL ENGINE AT A HIGH LEVEL OF BOOSTING
Authors: Parsadanov I.V. , Lal A.G. 
Published: November 2021

Based on the analysis and synthesis of previously performed theoretical and practical studies, the paper proposes a concept of combustion process organization in a boxer two-stroke diesel engine at a high level of boosting. Such diesel engines are produced in Ukraine and are widely used in land, sea and rail transport, as diesel generator plants. The implementation of this concept will ensure the reduction of the thermal stress of the cylinder piston group for these diesel engines, while improving fuel efficiency.
The features of the organization of the working process in a boxer two-stroke diesel engine are briefly considered. The contribution of Ukrainian, Russian and American scientists to the development and improvement of their mixing efficiency is noted.
Following the purpose of the research, which determines the choice of directions for the development and implementation of technical solutions for the simultaneous reduction of fuel consumption and thermal tension of the cylinder-piston group when forcing a boxer two-stroke diesel engine, it is proposed to use the amount of released heat as a criterion for evaluating the quality of combustion.
Based on the results of earlier studies, conceptual foundations for increasing the efficiency of the combustion process of a highly boosted boxer two-stroke diesel engine have been developed, which are directly related to the air supply, fuel supply, the rationale for choosing the shape of the combustion chamber are determined by the amount of heat released during combustion and the nature of its change in the crankshaft rotation angle.
RESEARCH OF THERMAL AND MASS-EXCHANGE PROCESSES IN GAS-LIQUID FILM ABSORBERS IN SURFACE-ACTIVE TECHNOLOGY
Authors: Dzevochko O. , Podustov M. , Dzevochko A. 
Published: November 2021

The article states that surfactants have an asymmetrically constructed molecule that contains hydrophilic and hydrophobic groups. The main department of surfactant production is the process of sulfation of organic matter with gaseous sulfur trioxide.
It is shown that the process of sulfation in gas-liquid film absorbers consists of the following stages: the process of mass transfer of sulfur trioxide from the gas stream to the liquid phase; the process of absorption of sulfur trioxide by organic matter with the passage of an exothermic chemical reaction; the process of heat exchange between the liquid phase and the gas stream; the process of heat exchange between the liquid phase and the flow of cooling water.
Studies of heat and mass transfer processes at these stages make it possible to select the necessary equations for the calculation of heat transfer coefficients, heat transfer coefficients and mass transfer coefficient.
It is recommended to calculate the heat transfer coefficient from liquid to gas by the equation when the diffusion and thermal Prandtl numbers are close to unity. The use of the classical equation to calculate the heat transfer coefficient from the liquid phase to the wall of the reaction tube did not give the desired result. Therefore, an equation was used that takes into account the properties of the gas-liquid flow as a whole. It is recommended to calculate the heat transfer coefficient from the reaction pipe wall to the cooling water flow according to the classical Nusselt equation.
Experimental data processing data for calculating the density and dynamic viscosity of the reaction mass along the length of the reactor are presented.
The equation for calculating the mass transfer coefficient was obtained by analyzing 6 equations of different authors who were engaged in the process of sulfation of organic substances. A mathematical description of the sulfation process in a film absorber was developed for analysis. During the development of the mathematical description, the balance equations of mass and heat transfer for the reaction tube were compiled. Based on the results of mathematical modeling, an equation was chosen that includes the tangential stress at the gas-liquid interface.
The results of mathematical modeling were compared with Gutierrez's experimental data and the results of Dabir's mathematical modeling. The obtained results will be used in mathematical modeling of the sulfation process in a film absorber.
PENGEMBANGAN SEBUAH PENGAJARAN RESPONSIF BUDAYA (CRT) PADA KELAS DRAMA (SEBUAH KOLABORASI MAHASIWA DALAM PEMENTASAN DRAMA CERITA LOKAL)
Authors: Hambandima Erny Selfina Nggala 
Published: November 2021

DEVELOPING A CULTURALLY RESPONSIVE TEACHING (CRT) ON TEACHING DRAMA ( A COLLABORATION ON STUDENTS’ LOCAL STORY DRAMA PERFORM)
ESNHAbstract: This study is meant to investigate how lecturer develop a culturally responsive teaching on drama class especially students’ collaborative of local story drama perform. The problem of this research is formulated as how does the lecturer develop CRT on teaching drama? The study was stimulated by the writer’s interest to examine the CRT on a collaboration of 5th semester students’ local story drama performance by understanding the local story through drama teaching whereas nowadays teaching also touch about the local content. The research subjects are 5th semester students from 3 different classes that the writer collaborate them in a collaboration team. The writer randomly collaborate the students by means of getting them to adapt, cooperate and create their own acting to be more fearless, creative in front of the stage. A qualitative research was conducted by observing the students’ activity and watching the video documenting students’ performance. From the data result the writer found that the drama class based CRT are the students learn within the context of different culture, students being the center in teaching and learning process, students adjusted the learning with the group members and the teacher being the mediator to succeed the students’ project. The conclusion is the students enrich their knowledge of historical story from different ethnics as well as they authentically know the differences local story among them. The suggestions are the educators should convey the local content in teaching and learning process in class based culturally responsive teaching.
Keywords: Developing, Culturally Responsive Teaching (CRT), Teaching Drama, Collaboration
Oral and IV Antibiotic Administration After Single-Stage Revision Shoulder Arthroplasty
Authors: Yao Jie J. , Jurgensmeier Kevin , Whitson Anastasia J. , Pottinger Paul S. , Matsen Frederick A. , Hsu Jason E. 
Published: November 2021

Background:
Following revision shoulder arthroplasty, postoperative antibiotics are selected before the results of intraoperative cultures become available. We determined infection-free survival, revision-free survival, complications, and patient-reported outcomes for patients selected to receive oral or intravenous (IV) antibiotics after revision arthroplasty.

Methods:
This study included 92 patients who had revision shoulder arthroplasty. IV antibiotics were administered if the surgeon had a high index of suspicion for infection, and oral antibiotics were given if there was a low suspicion. Antibiotic therapy was modified based on intraoperative culture results. Patient-reported outcomes and adverse events were documented at a mean of 4.1 years.

Results:
In selecting antibiotic therapy, surgeons correctly predicted the presence or absence of multiple positive cultures of specimens from the revision surgery in 72% of the 92 cases. Subsequent re-revision surgery was required in 17 (18%) of the patients; 8 of these 17 patients had ≥2 positive cultures at re-revision. Patients who initially received IV antibiotics and those who initially received oral antibiotics had similar revision-free (p = 0.202) and infection-free (p = 0.155) survivorship. Patients requiring a change from oral to IV antibiotics based on positive cultures had similar survivorship compared with those initially treated with IV antibiotics. The IV and oral antibiotic groups had similar postoperative Simple Shoulder Test (SST), American Shoulder and Elbow Surgeons (ASES), and satisfaction scores. Patients receiving IV antibiotics had a higher rate of antibiotic-related adverse events.

Conclusions:
Post-revision antibiotic therapy was associated with an infection-free survival rate of 91% at a mean of >4 years of follow-up. Infection-free survival, revision-free survival, and patient-reported outcomes were similar in high-risk patients placed on IV antibiotics and low-risk patients placed on oral antibiotics. Further study is needed to define the indications for IV or oral antibiotics after revision arthroplasty.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Media pembelajaran video produk kreatif dalam pembuatan softcase laptop produk kreatif di era pandemi covid-19
Authors: Astuti Yayuk  Dwi , Haryanti Nik 
Published: November 2021

ABSTRAK: Penggunaan media dalam proses pembelajaran dapat membangkitkan keinginan-keinginan dan minat yang baru, membangkitkan motivasi, dan rangsangan kegiatan belajar, bahkan membawa pengaruh-pengaruh psikologis terhadap siswa. Berkenaan dengan penyebaran Coronavirus Disease (covid 19) yang semakin meningkat maka kesehatan seluruh warga sekolah menjadi pertimbangan utama dalam pelaksanaan pembelajaran khususnya mengenai media pembelajaran secara daring. Dengan demikian, siswa harus punya pendamping belajar, hal ini terjadi karena nilai KKM siswa di sekolah minim. Terutama masalah pelajaran kewirausahaan siswa sebagian belum ada keinginan untuk berwirausaha. Dengan wujud media video tutorial ini dapat tumbuh imajinasi kreatifitas dari setiap siswa terkait wirausaha produk kreatif. Salah satu media yang dapat dimanfaatkan peserta didik untuk belajar mandiri adalah menggunakan media video produk kreatif wadah laptop. Penggunaan video sebagai media belajar dapat membuat peran guru ke arah yang lebih positif dan produktif. Guru dapat berbagi peran dengan media sehingga memiliki banyak waktu untuk memberi perhatian pada aspek-aspek edukatif lainnya, seperti membantu kesulitan belajar siswa, pembentukan kepribadian, memotivasi belajar, dan lain-lain.
MODEL INOVASI PEMBELAJARAN MAHASISWA BERKEBUTUHAN KHUSUS (MBK) BERBASIS VIDEO BERSUBTITLE
Authors: Faisal Estu Yulianto  , Bambang Kurnadi  , Hasan Basri  , Ukthi Raudhatul Jannah  , Zayyadi Moh 
Published: November 2021

Penelitian ini bertujuan untuk mengembangkan model pembelajaran secara daring yang ramah dan cocok bagi mahasiswa sesuai dengan kebutuhan khusus. Pengembangan model berbasis video yang digunakan dalam penelitian ini adalah model Desain Pembelajaran ADDIE (Analysis-Design-Develop-Implement-Evaluate). desain produk ini diantaranya: (1) RPS; (2) Materi ajar; (3) Video Pembelajaran; dan (4) Evaluasi Pembelajaran. Teknik pengumpulan data yang dilakukan pada penelitian ini dalam bentuk angket dan dokumentasi. Teknik analisis data yang digunakan dalam penelitian ini yaitu skala pengukuran menggunakan skala Likert. Hasil penelitian ini adalah karakteristik model pembelajaran pada kegiatan ini adalah penggunaan media pembelajaran berupa video pembelajaran bersubtitle yang digunakan untuk mempermudah pemahaman konsep kalkulus pada mahasiswa normal dan mahasiswa berkebutuhan khusus. Secara umum pembelajaran yang diberikan dapat diterima dengan baik oleh semua mahasiswa, khususnya mahasiswa berkebutuhan khusus dengan gangguan pendengaran.
Identification of a lncRNA-Related Competing Endogenous RNA Network in Recurrent Implantation Failure
Authors: Huang Kai , Shi Ying , Chen Gezi 
Published: November 2021

Abstract
Background
Impaired endometrial receptivity is supposed to be a major element leading to recurrent implantation failure (RIF). Numerous studies have identified that the lncRNAs-miRNAs-mRNAs regulation network functions in the generation of receptive uterus. Long non-coding RNAs could act as competing endogenous RNAs in the pathogenesis of RIF. However, our understanding of the underlying mechanism is still limited.
Results
Based on the RNA-Seq results, 617 DEmRNAs, 69 DElncRNAs and 107 DEmiRNAs were identified in the RIF group compared with the control group. To investigate the role of lncRNAs in RIF, we constructed a lncRNA related ceRNA network. A total of 3 lncRNAs, 8 miRNAs and 69 genes were identified. Above all, our study obtained 120 lncRNAs-miRNAs-mRNAs relationships in the ceRNA network. Among three hub lncRNAs, PART1 and PWRN1 were upregulated whereas PGM5P3-AS1 was downregulated in RIF endometrium. Meanwhile, three down-regulated miRNAs (hsa-miR-1207-5p, hsa-miR-134-5p, hsa-miR-1225-5p) and five up-regulated miRNAs (hsa-miR-30c-5p, hsa-miR-30b-5p, hsa-miR-145-5p, hsa-miR-21-5p, hsa-miR-196b-5p) were shown.
Conclusions
We constructed a lncRNA-related ceRNA network and identified three hub lncRNAs in recurrent implantation failure. The results may provide further understanding in the pathogenesis of RIF as well as potential diagnostic and therapeutic targets.
Tumor microenvironment-aware, single-transcriptome prediction of microsatellite instability in colorectal cancer using meta-analysis
Authors: Seo Mi-Kyoung , Kang Hyundeok , Kim Sangwoo 
Published: November 2021

Abstract
Detecting microsatellite instability (MSI) in colorectal cancers (CRCs) is essential since it is therapeutic strategy determinant feature, including immunotherapy and chemotherapy. Yet, no attempt has been made to exploit transcriptomic profile and tumor microenvironment (TME) of it to unveil MSI status in CRC. Hence, we developed a novel TME-aware, single-transcriptome predictor of MSI for CRC, called MAP (Microsatellite instability Absolute single sample Predictor). MAP was developed utilizing recursive feature elimination-random forest with 466 CRC samples from The Cancer Genome Atlas, and its performance was validated in independent cohorts, including 1118 samples. MAP showed robustness and predictive power in predicting MSI status in CRC. Additional advantages for MAP were demonstrated through comparative analysis with existing MSI classifier and other cancer types. Our novel approach will provide access to untouched vast amounts of publicly available transcriptomic data and widen the door for MSI CRC research and be useful for gaining insights to help with translational medicine.
Sickness Absence Culture: A Scoping Review
Authors: Pukstad Erlend , Lorentzen Sofie , Låg Torstein , Mykletun Arnstein 
Published: November 2021

Abstract
Background: Several studies show that the absence behavior of co-workers’ influence the absence rates of individual group members so that an employee is more likely to be absent when co-workers are often absent. To our knowledge, there are no systematic scoping reviews or other reviews on the concept of sickness absence culture. The objective of this review is to identify and map existing literature on sickness absence culture. We will also investigate what methods and designs are used.Methods: We will be conducting a systematic scoping review with the aim of getting a broad overview of the preexisting literature. This scoping review will consider any publication on sickness absence culture in the field of human sciences, including also reviews, original research, and opinion pieces. The review will be conducted in accordance with the Joanna Briggs Institute (JBI) methodology for scoping reviews and a populated PRISMA-P checklist (Additional file 1). Two reviewers will independently screen all abstracts for inclusion. We will search the electronic databases: MEDLINE, Embase, PsycINFO, Clarivate Web of Science, BASE and CINAHL. We will use Covidence for data screening and extraction. The final stage will include a narrative synthesis of the data.Discussion: The results of this scoping review will contribute to identifying and mapping the existing literature on sickness absence culture, which could facilitate future research on the topic. Systematic review registration: Not registered in publicly accessible registry.