bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multiperspective and Multimethod Evaluation of Flexible and Integrative Psychiatric Care Models in Germany: Study Protocol of a Prospective, Controlled Multicenter Observational Study (PsychCare)
Authors: Soltmann Bettina , Neumann Anne , March Stefanie , Weinhold Ines , Häckl Dennis , Kliemt Roman , Baum Fabian , Romanos Marcel , Schwarz Julian , von Peter Sebastian , Ignatyev Yuriy , Arnold Katrin , Swart Enno , Heinze Martin , Schmitt Jochen , Pfennig Andrea 
Published: June 2021

Background: New cross-sectoral mental health care models have been initiated in Germany to overcome the fragmentation of the German health care system. Starting in 2013, flexible and integrative psychiatric care model projects according to §64b SGB V German Social Law (FIT64b) have been implemented. The study “PsychCare” combines quantitative and qualitative primary data with routine health insurance data for the evaluation of these models. Effects, costs and cost-effectiveness from the perspectives of patients, relatives and care providers are compared with standard care. Additionally, quality indicators for a modern, flexible and integrated care are developed. This article describes the rationale, design and methods of the project.Methods: “PsychCare” is built on a multiperspective and multimethod design. A controlled prospective multicenter cohort study is conducted with three data collection points (baseline assessment, follow-up after 9 and 15 months). A total of 18 hospitals (10 FIT64b model and 8 matched control hospitals) have consecutively recruited in- and outpatients with pre-specified common and/or severe psychiatric disorders. Primary endpoints are differences in change of health-related quality of life and treatment satisfaction. Sociodemographic and service receipt data of the primary data collection are linked with routine health insurance data. A cost-effectiveness analysis, a mixed method, participatory process evaluation by means of qualitative surveys and the development of quality indicators are further elements of “PsychCare.”Discussion and Practical Implications: The results based on data from different methodological approaches will provide essential conclusions for the improvement of hospital based mental health care in Germany. This should result in the identification of key FIT64b elements that can be efficiently implemented into standard care in Germany and re-structure the care strongly aligned to patient needs.Clinical Trial Registration: German Clinical Trial Register, identifier DRKS 00022535.
Case Report: Superior Vena Cava Resection and Reconstruction for Invasive Thyroid Cancer: Report of Three Cases and Literature Review
Authors: Chen Wenjie , Lei Jianyong , Wang Yichao , Tang Xiaojun , Liu Bin , Li Zhihui , Zhou Qinghua 
Published: June 2021

Background: Thyroid cancer with massive invasion into the cervical and mediastinal great veins is extremely rare, and the surgical treatment is controversial, thus posing a great challenge for head and neck surgeons. Here, we report our successful experiences in reconstructing the superior vena cava (SVC) system to treat thyroid cancer with an extensive tumor thrombus growing intraluminally into the SVC.Case Presentation: From September 2019 to September 2020, three patients with superior vena cava syndrome(SVCS) caused by tumor thrombus invasion from thyroid cancer were continuously included in this series. After preoperative evaluation, radical resection and reconstruction of the SVC system with expanded polytetrafluoroethylene (EPTFE) grafts were performed. In addition, bypass support from the right internal jugular vein to the right femoral vein was routinely prepared intraoperatively to prevent a rise in central venous pressure (CVP). Postoperatively, SVC-related syndrome improved immediately after the operation. Imaging examination showed good function of the reconstructed venous system. The patients recovered well with no surgical complications and remain under continuous follow-up.Conclusions: Tumor growth into the SVC does not seem to be an absolute contraindication for surgery for thyroid carcinoma. Comprehensive treatment, including reconstruction of the SVC, is effective for relieving symptoms and preventing disease progression and is thus worth advocating. In addition, bypass support from the internal jugular vein to the femoral vein is easy to implement and can improve the safety of the operation.
Nitrate Modulates Lateral Root Formation by Regulating the Auxin Response and Transport in Rice
Authors: Wang Bobo , Zhu Xiuli , Guo Xiaoli , Qi Xuejiao , Feng Fan , Zhang Yali , Zhao Quanzhi , Han Dan , Sun Huwei 
Published: June 2021

Nitrate (NO3-) plays a pivotal role in stimulating lateral root (LR) formation and growth in plants. However, the role of NO3- in modulating rice LR formation and the signalling pathways involved in this process remain unclear. Phenotypic and genetic analyses of rice were used to explore the role of strigolactones (SLs) and auxin in NO3--modulated LR formation in rice. Compared with ammonium (NH4+), NO3- stimulated LR initiation due to higher short-term root IAA levels. However, this stimulation vanished after 7 d, and the LR density was reduced, in parallel with the auxin levels. Application of the exogenous auxin α-naphthylacetic acid to NH4+-treated rice plants promoted LR initiation to levels similar to those under NO3- at 7 d; conversely, the application of the SL analogue GR24 to NH4+-treated rice inhibited LR initiation to levels similar to those under NO3- supply by reducing the root auxin levels at 10 d. D10 and D14 mutations caused loss of sensitivity of the LR formation response to NO3-. The application of NO3- and GR24 downregulated the transcription of PIN-FORMED 2(PIN2), an auxin efflux carrier in roots. LR number and density in pin2 mutant lines were insensitive to NO3- treatment. These results indicate that NO3- modulates LR formation by affecting the auxin response and transport in rice, with the involvement of SLs.
Formação profissional: cuidado ao paciente oncológico sem possibilidade terapêutica na Atenção Básica
Authors: Flores Thamires Graciela , Silva Kauana Flores da , Giaretton Daynah Waihrich Leal , Weiller Teresinha Heck , Pucci Vanessa Rodrigues 
Published: June 2021

Objeto: formação profissional para o cuidado ao paciente sem possibilidade terapêutica na atenção básica. Objetivo: O presente estudo objetivou discutir a formação de profissionais da rede de Atenção Básica na atuação com pacientes oncológicos sem possibilidades terapêuticas, tendo em vista a demanda apresentada no campo da saúde em relação a esses pacientes e o desafio da estruturação de uma linha de cuidado que proporcione a integralidade da atenção aos mesmos. Método: Trata-se de um estudo transversal descritivo com abordagem qualitativa, realizado por meio de entrevistas com profissionais de saúde da região oeste de Santa Maria Rio Grande do Sul e Unidade de Pronto de Atendimento e analisados por meio da análise de conteúdo temática. Resultados: Foram entrevistados 85 profissionais de saúde e observou-se que os profissionais da rede de Atenção Básica não se sentem qualificados para atender os pacientes oncológicos sem possibilidades terapêuticas, devido à formação profissional e a qualificação para o trabalho não atenderem esta demanda. Conclusão: Os cursos de graduação e de formação de profissional da área da saúde, bem como os gestores através das capacitações na rede de Atenção Básica, devem atentar para essa nova necessidade no campo da saúde.
Descritores: Atenção Primária à Saúde, Saúde Pública, Oncologia, Cuidados Paliativos.
A review on the trend of livestock breeds in Laos
Authors: Xayalath Somsy , Mujitaba Malam Abulbashar , Ortega Art David Sol Valmoria , Rátky József 
Published: June 2021

When the livestock sector is considered an essential role in farmers' livelihood, and local breeds are still the critical component of animal breeding in Laos. Thus, there is a need to review the previous, current situation and prospects for Laos' livestock production. It aimed to study the different traits among the existing dominant local and improved livestock breeds (cattle, pig, and goat) and a more in-depth study on the livestock sector's previous evolving and prospects. Our findings revealed that the general trend of livestock population in Laos increased year-by-year for over 45 years, except for 1995 to 2000. It was decreased by almost 22% due to the new national strategy on economic revolution. The first foreign breeds were introduced into Laos, i.e., Large White, Landrace, and Duroc in 1980, Red Sindhi bulls in 1998, the frozen semen of Red Brahman 2003, and Bach Thao goats between 2001 to 2003. Unfortunately, many data are still not precise for introducing other foreign breeds like Boer goats, Thai Grey and Red Brahman. There were many missing data on the improvement of livestock breeds in Laos, including the local and improved breeds' reproductive and productive performance, which needs more study and research. We conclude that the semi-complex farm operation should be applied to improve livestock breeding and their productions in Laos.
A eficácia da acupuntura no tratamento da hipertensão arterial sistêmica: ensaio clínico randomizado/ The effectiveness of acupuncture in the treatment of systemic arterial hypertension: randomized clinical trial
Authors: Rochadel Daniel Ullmann , Barbisan Juarez Neuhaus , Goldmeier Silvia 
Published: June 2021

A Organização Mundial de Saúde (OMS) reconhece a acupuntura como intervenção terapêutica em seres humanos em algumas condições clínicas e já é comprovada como no tratamento da dor. Porém, em algumas patologias, como a Hipertensão Arterial Sistêmica, ainda necessita de evidências científicas. Objetivos: Verificar a eficácia de uma técnica de acupuntura em pacientes hipertensos. Material e Métodos: Ensaio clínico randomizado controlado por placebo realizado no período de abril de 2018 a outubro de 2018. Pacientes hipertensos, conforme critério da Sociedade Brasileiros de Cardiologia, foram randomizados para o grupo controle acupuntura (grupo 1) e acupuntura sham - placebo (grupo 2). Na intervenção foi usada a Acupuntura Tradicional Chinesa com 9 agulhas, nos pontos IG4, Pc6, C7, F3 e VG20. O grupo 2 - Acupuntura sham (placebo) as agulhas foram inseridas em regiões que não apresentam pontos regulares definidos nos meridianos. A Monitorização Ambulatorial de Pressão Arterial foi utilizada para monitorar a PA e avaliar o efeito da sessão de acupuntura em 3, 6 e 24 horas. As variáveis foram expressas em percentual ou valor absoluto; as contínuas como média ± desvio padrão ou mediana e intervalo interquartil e análise de variância será utilizado. Resultados: Cem pacientes ingressaram no estudo. 86 pacientes que concluíram. A média de idade 59(± 10.10) anos de idade. 65(75,5%) mulheres, sendo 46 (54%) do grupo intervenção (verun). Observou-se PAS do grupo intervenção nas horas de análises foram em 3, 6 e 24 horas, respectivamente reduzindo a PAS em 1,64 mmHg; 9,55mmHg; 6,24mmHg mais baixo que o grupo controle com “p” significativo nas horas 3,6 e 24, enquanto a PAD do grupo intervenção reduziu em 3, 6 e 24 horas, respectivamente 3,98mmHg, 10,23mmHg, 6,7mmHg mais baixo também relação ao grupo controle com “p” significativo nas horas 6 e 24. Conclusões: Os resultados deste estudo demonstraram que a acupuntura pode diminuir a pressão arterial em pacientes com Hipertensão Arterial Sistêmica. Foi estatisticamente significativa nos grupos de intervenção na sexta hora até a vigésima quarta hora.
AN ITERATIVE ALGORITHM FOR FINDING THE MINIMUM NORM POINT IN THE SOLUTION SET OF SPLIT FIXED POINT PROBLEM
Authors: Nghĩa Nguyễn Trung , Thắng Nguyễn Tất 
Published: June 2021

Bài toán chấp nhận tách và bài toán bất đẳng thức biến phân có nhiều ứng dụng quan trọng trong các lĩnh vực như xử lý tín hiệu, xử lý ảnh, điều khiển tối ưu và nhiều lĩnh vực khác. Ở đây, chúng tôi quan tâm tới một bài toán hai cấp, đó là bài toán tìm điểm có chuẩn nhỏ nhất trên tập nghiệm của bài toán điểm bất động tách. Bài toán tìm điểm có chuẩn nhỏ nhất là trường hợp riêng của bài toán bất đẳng thức biến phân, trong đó ánh xạ giá F là ánh xạ đồng nhất của không gian Hilbert. Trong bài báo này, chúng tôi trình bày một phương pháp lặp hiện để xấp xỉ nghiệm của bài toán trên. Phương pháp được xây dựng dựa trên kết quả đã được trình bày bởi các tác giả Trần Việt Anh và Lê Dũng Mưu năm 2016, đó là sự kết hợp giữa phương pháp chiếu giải bất đẳng thức biến phân và phương pháp Krasnoselskii–Mann giải bài toán điểm bất động của các ánh xạ không giãn. Định lý về sự hội tụ mạnh của thuật toán được chứng minh. Ở cuối bài báo, chúng tôi trình bày một ví dụ số để minh họa cho sự hội tụ của phương pháp.
PEMANFAATAN LIMBAH KOKON ULAT SUTRA (Bombyx mori.L) SEBAGAI SERUM ANTI-AGING
Authors: Paembonan Rosa , Salama Nurul , Gazali Al 
Published: June 2021

Kokon merupakan produk yang dihasilkan oleh ulat sutera (Bombyx mori), banyak mengandung serisin yang membungkus filamen pada serat fibroin pada kokon, bobotnya 20-30% dari bobot total kokon. Serisin ini merupakan salah satu antioksidan yang bermanfaat mengurangi proses aging yang disebabkan radikal bebas. Serisin didapatkan dari kokon bekualitas baik maupun kokon cacat, diharapkan dapat diformulasi menjadi sediaan serum limbah kokon sebagi anti-aging (anti penuaan kulit). Serum adalah salah satu sediaan kosmetik berbentuk gel atau cair yang digunakan untuk produk anti-aging, maka dilakukan penelitian pemanfaatan limbah kokon ulat sutera (bombyx mori) sebagai serum anti-aging.. Hasil yang diharapkan yaitu diperoleh sediaan serum yang berpotensi menjadi serum anti-aging. Metode yang digunakan dalam pelaksanaan penelitian ini adalah literatur review didapatkan bahwa Kokon ulat sutera memiliki kandungan senyawa serisin yang cukup tinggi yang belum diolah menjadi sebuah produk, Senyawa serisin ini biasanya dibuat sebagai sediaan antioksidan, pemutih, tabir surya, antiagent, antibakteri dan penyembuh. Kurangnya pemanfaatan limbah kokon ulat sutra merupakan masalah yang harus dikaji dan perlu dicarikan solusi dengan memanfaatkan limbah kokon ulat sutra menjadi serum anti-aging.
Origen del concepto de resiliencia y crítica a su apropiación en los proyectos educativos de Medellín
Authors: Foronda Macías Diana Patricia , Vélez de la Calle Claudia 
Published: June 2021

El concepto de resiliencia ha evolucionado teóricamente; en principio, se consideró como una capacidad; luego como un proceso, para responder a una serie de situaciones que afectan a los individuos según un contexto y un referente histórico; en la actualidad se concibe como una propuesta esperanzadora con alternativas de intervención para contribuir a la formación de sujetos y comunidades capaces de superar las adversidades, e incluso salir fortalecidos de ellas.
En este estudio de caso de enfoque cualitativo, tipo no experimental y desarrollado bajo el método hermenéutico-crítico, se comprende el origen del concepto resiliencia y su aplicación en el ámbito educativo, específicamente en el contexto de tres proyectos educativos de la ciudad de Medellín que atienden grupos socioeducativos vulnerables: Caminos para la resiliencia, Familias fuertes y resilientes, e Ícaro.
Finalmente, se realiza un análisis crítico del concepto; y se propone como noción alternativa, la resistencia.
El síndrome de burnout y sus consecuencias en la salud mental de los docentes
Authors: García Rodríguez Reynier , Sánchez Parrales Ligia Vanessa , Dueñas Segovia Francisco , Meza Macías Alejandro 
Published: June 2021

La educación es un proceso que demanda docentes preparados, capacitados, poseedores de valores, pero también con una adecuada salud mental. Estos aspectos son medulares en la formación de los niños, niñas y jóvenes. El Instituto Superior Tecnológico, propuso un proyecto de investigación cuyo tema es: Alternativas de desafíos contra el síndrome Burnout. La propuesta pretende mejorar la salud mental y emocional dirigida a los docentes de Portoviejo- Manabí, con un alcance de dos años, que culmina en el 2022. La propuesta es innovadora, pertinente, actual y contextualizada, que responde a las necesidades de la provincia y del cantón. El objetivo del estudio fue proponer un sistema de acciones encaminado a la prevención del síndrome de burnout en los docentes de unidades educativas fiscales del cantón Portoviejo. Se aplicó una metodología inherente a un estudio descriptivo, prospectivo y transversal en 200 docentes de instituciones fiscales, donde los docentes se encontraron sensiblemente afectados, los principales síntomas identificados fueron, agotamiento físico y mental, falta de motivación absoluta, sensibilidad a la crítica, pérdida de energía, descenso en la productividad laboral y estrés. En la teoría hubo divergencia de las opiniones, considerándose el síndrome de burnout como una patología mental crónica y/o aguda, la investigación permitió valorarla como aguda, en tanto se intervenga en pos de la salud mental. Se concluye que la encuesta arrojó información dirigida a una propuesta operativa de sistema de acciones encaminado a la prevención del síndrome de burnout en los docentes de unidades educativas fiscales del cantón Portoviejo.
Experiencia en la terapia de pacientes pediátricos con Leucemia Linfoblástica Aguda en SOLCA de Manabí
Authors: Villaprado Meza Cecilia Lissete , Cedeño Mera Richard Geovanny 
Published: June 2021

Las leucemias se distinguen por infiltración de células neoplásicas del sistema hematopoyético en la médula ósea, sangre y otros tejidos. El objetivo del estudio fue describir la experiencia del Hospital Oncológico “Dr. Julio Villacreses Colmont”). de SOLCA al aplicar la guía de tratamiento del grupo SEHOP- PETHEMA 2013 fundamentada con los últimos avances diagnósticos y terapéuticos desarrollados por el grupo alemán Berlín Frankfurt Muenster (BFM) en pacientes pediátricos con Leucemia Linfoblástica Aguda. Se realizó un estudio de diseño longitudinal con 94 pacientes pediátricos entre 1 y 18 años con diagnóstico de leucemia linfoblástica aguda que recibieron tratamiento con la guía de la Sociedad Española de Hematología y Oncología Pediátrica. Los resultados destacan que de los 94 niños, 54% pertenecían al género masculino, el rango predominante fue de 2 a 6 años, el inmunofenotipo más frecuente (90%) fue LLA-B COMÚN, en el estudio citogenético 79% presento una Diploidia, y 94% no presentó reordenamientos moleculares, la evaluación de la respuesta a los corticoides en el día +8 fue buena en el 94% de los niños, en el día +15 68% alcanzaron la remisión completa (RC < 0,01%) .Se estadificaron 1 paciente en riesgo estándar, 75 en riesgo intermedio y 18 en riesgo alto. Se concluye que la guía SEHOP se puede cumplir eficientemente, sin embargo se deben realizar estudios corporativos a nivel país que permitan identificar nuestras falencias y crear estrategias para optimizar el soporte integral del inmunocomprometido y obtener terapias de salvataje en niños refractarios y recaídos.
Acute and Chronic Periocular Massage for Ocular Blood Flow and Vision: a Randomized Controlled Trial
Authors: Hayashi, PhD Naoyuki , Du, MSc Lanfei 
Published: June 2021

Introduction: The ocular blood flow (OBF) is responsible for supplying nutrition to the retina, which plays a fundamental role in visual function. Massage is expected to improve the blood flow and, consequently, vascular function. The aim of this study was to determine the shortterm and long-term effects of periocular massage on OBF and visual acuity.
Methods: The OBF and visual acuity were measured in 40 healthy adults aged 20–30 years before and after massage, and also in control subjects. Three massage methods were used: applying periocular acupressure (“Chinese eye exercise”: CE), using a facial massage roller (MR), and using an automated eye massager (AM). The OBF and visual acuity were first measured before and after applying each type of massage for 5 min. Eye massage was then applied for 5 min once daily over a 60-day period, while the control group received no massage. The same measurements were then performed again.
Results: Performing short-term periocular massage showed significant interactions in time and massage effects on visual acuity in CE and AM groups, and on OBF in AM group, while 60-day massage period exerted no significant effects. No significant relationship was found between OBF and visual acuity changes.
Conclusions: These results suggest that short-term periocular massage with Chinese eye exercise and automated eye massager can improve OBF and visual acuity, although no causal relationship was supported.
Giant Metrewave Radio Telescope Detection of Hi 21 cm Emission from Star-forming Galaxies at z ≈ 1.3
Authors: Chowdhury Aditya , Kanekar Nissim , Das Barnali , Dwarakanath K. S. , Sethi Shiv 
Published: June 2021

Abstract
We report a ≈400 hr Giant Metrewave Radio Telescope (GMRT) search for Hi 21 cm emission from star-forming galaxies at z = 1.18–1.39 in seven fields of the DEEP2 Galaxy Survey. Including data from an earlier 60 hr GMRT observing run, we co-added the Hi 21 cm emission signals from 2841 blue star-forming galaxies that lie within the FWHM of the GMRT primary beam. This yielded a 5.0σ detection of the average Hi 21 cm signal from the 2841 galaxies at an average redshift 〈z〉 ≈ 1.3, only the second detection of Hi 21 cm emission at z ≥ 1. We obtain an average Hi mass of 〈M
HI
〉 = (3.09 ± 0.61) × 1010 M⊙ and an Hi-to-stellar mass ratio of 2.6 ± 0.5, both significantly higher than values in galaxies with similar stellar masses in the local universe. We also stacked the 1.4 GHz continuum emission of the galaxies to obtain a median star formation rate (SFR) of 14.5 ± 1.1 M⊙yr−1. This implies an average Hi depletion timescale of ≈2 Gyr for blue star-forming galaxies at z ≈ 1.3, a factor of ≈3.5 lower than that of similar local galaxies. Our results suggest that the Hi content of galaxies toward the end of the epoch of peak cosmic SFR density is insufficient to sustain their high SFR for more than ≈2 Gyr. Insufficient gas accretion to replenish the Hi could then explain the observed decline in the cosmic SFR density at z < 1.
Dwarf Satellites of High-z Lyman Break Galaxies: A Free Lunch for JWST
Authors: Gelli Viola , Salvadori Stefania , Ferrara Andrea , Pallottini Andrea , Carniani Stefano 
Published: June 2021

Abstract
We show that the James Webb Space Telescope (JWST) will be able to detect dwarf satellites of high-z Lyman break galaxies (LBGs). To this end, we use cosmological simulations following the evolution of a typical M
⋆ ≃ 1010
M
⊙ LBG up to z ≃ 6, and analyze the observational properties of its five satellite dwarf galaxies (107
M
⊙ < M
⋆ < 109
M
⊙). Modeling their stellar emission and dust attenuation, we reconstruct their rest-frame ultraviolet-optical spectra for 6 < z < 6.5. JWST/NIRCam synthetic images show that the satellites can be spatially resolved from their host, and their emission is detectable by planned deep surveys. Moreover, we build synthetic spectral energy distributions and color–magnitude diagrams for the satellites. We conclude that the color F200W–F356W is a powerful diagnostic tool for understanding their physical properties once they have been identified. For example, F200W–F356W ≲ −0.25 can be used to identify star-bursting (SFR ∼ 5 M
⊙ yr−1), low-mass (M
⋆ ≲ 5 × 108
M
⊙) systems, with ∼80% of their stars being young and metal poor

].