bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mapping The Life-History, Development, And Survival of Spotted Lantern Fly In Occupied And Uninvaded Ranges
Authors: Maino James Louis , Schouten Rafael , Lye Jessica C , Umina Paul A. , Reynolds Olivia L. 
Published: June 2021

Abstract
The Spotted Lantern Fly (SLF), Lycorma delicatula (Hemiptera: Fulgoridae), is a sap feeding pest native to southeast Asia that has become a global biosecurity threat following invasions into South Korea, Japan, and the United States in the last two decades. Environmental niche modelling has demonstrated considerable potential for further range expansions, including into Australia and Europe. Further analysis on the potential seasonal life-history and survival of this pest in its invasive range can inform monitoring programs and is a next step in biosecurity preparedness. Here, we incorporated eco-physiological information on the development and survival of SLF life stages across temperature regimes. Using gridded climatic data, we then mapped the developmental sequence of SLF across ranges already occupied in China, South Korea, and the United States, as well as uninvaded ranges in Australia and Europe. The model was able to capture global observations of the seasonal appearance of SLF and highlight regional and seasonal vulnerabilities in regions at risk of invasion. Policy makers can use these results to make science-based biosecurity decisions and target preparedness activities through improved life-history predictions in its invasive range.
Mixed logit model based on nonlinear random utility functions: A transfer passenger demand prediction method on overnight D-trains
Authors: Han Bing , Ren Shuang 
Published: June 2021

Abstract
In recent years, with the development of high-speed railway in China, the operating mileage and passenger transport capacity have increased rapidly. Due to the high density of trains in the daytime, we usually set up skylights at night within 0:00-6:00 on high-speed railway for comprehensive maintenance, which contradict with the operation demand of D-series overnight high-speed trains (overnight D-trains for short). In order to dynamically adjust the operation plan of overnight D-trains with skylights coordinately, it is necessary to predict the passenger demand of newly-added overnight D-trains. Therefore, the purpose of this paper is to predict transfer passenger demand by formulating a mixed logit model based on nonlinear random utility functions for different transport modes. Firstly according to Maximum Simulated Likelihood Method, the likelihood function of this mixed logit model is proposed to maximize the overall utility value of different passenger groups. And then we adopt Metropolis-Hastings Algorithm to iteratively solve the probabilities of discrete random variables in utility functions. After that, we estimate the unknown distributions of elements in parameter vectors and solve the optimal solution of this model by traditional algorithms, basic heuristic algorithms and improved heuristic algorithms including Imporved Fireworks-Simulated Annealing Algorithm which is proposed in this paper, respectively. Finally, a real-world instance with related data of Beijing-Shanghai corridor, is implemented to demonstrate the performance and effectiveness of the proposed approaches.
A Novel LSSVM Model Integrated with GBO Algorithm to Assessment of Water Quality Parameters
Authors: Kadkhodazadeh Mojtaba , Farzin Saeed 
Published: June 2021

Abstract
In this study, a novel least square support vector machine (LSSVM) model integrated with gradient-based optimizer (GBO) algorithm is introduced for assessment of water quality parameters. For this purpose, three stations including Ahvaz, Armand, and Gotvand in the Karun river basin have been selected to model electrical conductivity (EC), and total dissolved solids (TDS). First, to prove the superiority of the LSSVM-GBO algorithm, the performance is evaluated with three benchmark datasets (Housing, LVST, Servo). Then, the results of the new hybrid algorithm were compared with those of artificial neural network (ANN), adaptive neuro-fuzzy interface system (ANFIS), and LSSVM algorithms. Input combination for assessment of water quality parameters EC and TDS consists of Ca+ 2, Cl-1, Mg+ 2, Na+ 1, SO4, HCO3, sodium absorption ratio (SAR), sum cation (Sum.C), sum anion (Sum.A), PH, and Q. The modelling results based on evaluation criteria showed the significant performance of LSSVM-GBO among all benchmark datasets and algorithms. Other results showed that in Ahvaz station, Sum.C, Sum.A, and Na+1 parameters, and in Gotvand and Armand stations, Sum.C, Sum.A, and Cl-1 parameters have the greatest impact on modelling EC and TDS parameters. In the next step, EC and TDS modelling was performed based on the best input combination and the best algorithm in different time delays. Based on the results, the highest accuracy of modelling EC and TDS parameters in Gotvand station was [0] month time delays.
Navigating the local foodscape: Qualitative investigation of food retail and dietary preferences in Kisumu and Homabay Counties, western Kenya
Authors: Musuva Rosemary M. , Foley Louise , Wadende Pamela , Francis Oliver , Turner-Moss Eleanor , Were Vincent , Obonyo Charles 
Published: June 2021

Abstract
Introduction: Non-communicable diseases have risen markedly over the last decade. A phenomenon that was mainly endemic in high income countries has now visibly encroached in low and middle-income settings. A major contributor to this is a shift towards unhealthy dietary behavior. The aim of this study was to examine the complex interplay between individual characteristics and the environment to understand how these influenced food choices and practices in Western Kenya.Methods: This study used semi-structured guides to conduct focus group discussions with both male and female members of the community, capturing various socioeconomic groups, from Kisumu and Homabay Counties to further understand their perspective on influences of dietary behavior. Narratives were obtained using digital voice recorders, transcribed verbatim and translated to English. Data analysis adopted an exploratory and inductive analysis approach. Coded responses were analyzed using NVIVO 12 PRO software.Results: From the community’s perspective, the source of food was mainly influenced by individual characteristics such as the cost of goods, the individual’s perspective of the variety of food outlets and the freshness of produce. The major external influence was cited as distance to food vendors. Although participants understood what constitutes a healthy meal, a majority of participants in Kisumu spoke about providing for their family and consuming unbalanced diets due to budgetary constraints. For the majority of households, the woman was the food purchaser and determined day to day meals – reflecting traditional gender roles in the family. Foods consumed in the home were influenced mainly by perceived satiety and cost. Other factors included religion, special occasions and seasons.Conclusion: Although traditional markets and foods are still popular, there is a steady increase in the preference for global food brands and processed food and drink. Given that a major influence on choice of food source is distance and cost, there is a need for policy makers to ensure easy access to traditional markets and promotion of local healthier choices.
Chromatin Accessibility Reveals Potential Prognostic Value of the Peak Set Associated with Smoking History in Patients with Lung Adenocarcinoma
Authors: Liang Han , Deng Jianlian , Luo Tian , Luo Huijuan , Wu Xuan , Ye Yiwang , Wang Shubin , Li Fuqiang , Wu Kui , Lin Cong 
Published: June 2021

Abstract
Considerable differences in molecular characteristics have been defined between non-smoker and smokers in patients with lung adenocarcinoma (LUAD), yet studies of open chromatin patterns associated with LUAD progression caused by smoking are still lacking. Here, we constructed a novel network based on correlations between each ATAC-seq peak from TCGA data using our previously developed algorithm. Subsequently, principal component analysis was performed on LUAD samples with retained peaks filtered by the correlation network and pathway analysis was conducted for potential pathways identification. We identified a set of peaks that discriminated smokers in LUAD patients according to levels of exposure to tobacco quantified in pack-years, and also significantly associated with progression-free survival and overall survival of these patients. We then investigated the gene set related to those peaks and found that the comprising genes are strongly associated with LUAD development, such as B3GNT3, ACTN4 and CLDN3. They are consistent with the important roles for the associated pathways in LUAD oncogenesis induced by smoking, including glycosphingolipid biosynthesis and tight junction pathways. In summary, our study may provide valuable insights on exploration of ATAC-seq peaks and on smoking-related LUAD carcinogenesis from a perspective of open chromatin changes.
Propagation of Chirped Sinh-Gaussian Beams in Uniaxial Crystals Orthogonal to the Optical Axis
Authors: BAYRAKTAR Mert 
Published: June 2021

Abstract
This article includes intensity evolutions and phase changes of chirped sinh-Gaussian(CSG) beam propagating in uniaxial crystal orthogonal to optical axis. Received field expression is calculated utilizing Huygens-Fresnel integration. We see that chirped parameter brings decentered intensity distribution. By adjusting the decay factors, higher peak intensity can be obtained at the receiver side. Broken phase at near field is corrected at phase field. Phase change and amount of circles can be controlled by decay factor and chirped parameter. We hope that our results are helpful for scientist working on optical tracking.
GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors
Authors: Helness Anne , Fraszczak Jennifer , Joly-Beauparlant Charles , Bagci Halil , Trahan Christian , Arman Kaifee , Shooshtarizadeh Peiman , Chen Riyan , Ayoub Marina , Côté Jean-François , Oeffinger Marlene , Droit Arnaud , Möröy Tarik 
Published: June 2021

Abstract
GFI1 is a SNAG-domain, DNA binding transcriptional repressor which controls myeloid differentiation, in particular the formation of neutrophils. Here we show that GFI1 interacts with the chromodomain helicase CHD4 and other components of the “Nucleosome remodeling and deacetylase” (NuRD) complex. In granulo-monocytic precursors, GFI1, CHD4 or GFI1/CHD4 complexes occupy sites of open chromatin enriched for histone marks associated with active transcription suggesting that GFI1 recruits the NuRD complex to target genes that are regulated by active or bivalent promoters and active enhancers. Our data also show that GFI1 and GFI1/CHD4 complexes occupy promoters of different sets of genes that are either enriched for IRF1 or SPI-1 consensus sites, respectively. During neutrophil differentiation, overall chromatin closure and depletion of H3K4me2 occurs at different degrees depending on whether GFI1, CHD4 or both are present, indicating that GFI1 affects the chromatin remodeling activity of the NuRD complex. Moreover, GFI1/CHD4 complexes regulate chromatin openness and histone modifications differentially to enable regulation of target genes affecting the signaling pathways of the immune response or nucleosome organization or cellular metabolic processes.
Ecophysiological Effects Induced by an Oligophagous Insect Herbivore in an Early Spring Geophyte
Authors: Sajna Nina , Štruc Tjaša , de Groot Maarten 
Published: June 2021

Abstract
Insect herbivores, whose larval stages live and feed inside a plant leaf, are expected to have an impact on the leaf beyond the actual tissue damage. They might influence leaf photosynthesis. Here, we provide a brief insight by studying a simple model relationship between the spring geophyte ramsons Allium ursinum with short-lived green leaves and its oligophagous, leaf-mining hoverfly Cheilosia fasciata. We expected that the effect of leaf miners on short-lived leaves could interfere with resource allocation for the next season. Measurements of leaf greenness and chlorophyll fluorescence were performed to evaluate the stress impact of leaf miner damage upon photosynthesis during the short vegetative season of ramsons. Results showed that the onset of leaf senescence occurred earlier in infested leaves, which was also indicated by lower maximum efficiency of photochemistry compared to non-infested leaves. There was no evidence that infested leaves were able to compensate for the damage by increasing the rate of photosynthesis. Given the short lifespan of leaves and the earlier onset of senescence in infested leaves, we discuss two differential hypotheses: negative effects for the plant if the larvae have already left the mine, and negative effects for the leaf miner if the larvae are still developing inside the leaf.
Use Of Plant Growth-Promoting Bacteria And Humic Acids For Phytostabilization of Acid-Generating Mining Wastes
Authors: Bratkova Svetlana , Nikolova Katerina , Genova Petya , Angelov Anatoliy 
Published: June 2021

Abstract
Generation of acidic mine drainage is a major environmental problem in areas with mining waste. The cost-effective method for reclaiming of acid-generating mining wastes is a vegetation cover. Using plant growth-promoting bacteria (PGPR) and humic acid in remediation have several beneficial effects. The application of both humic substances and PGPR resulted in a decrease in Cu, Fe, Zn and sulfate concentrations in a variety of drainage water samples. Both PGPR and humic acid improve plant growth when used separately, however, the combination of both treatments has the most positive effect on fresh biomass yield – between 22% and 43 % and dry biomass of plants – between 31% and 41 %. Furthermore, addition of Bacillus and Pseudomonas bacteria, in combination with humic acids, to poor soil for reclamation improved grass mineral nutrition and reduced Cu and Zn uptake. The treatment with PGPR and humic acids significantly increased the uptake of nitrogen, phosphorus and potassium by plants.
Selection of Nuclear Genotypes Associated with the Thermo-inducibility of Owen-type Cytoplasmic Male Sterility in Sugar Beet (Beta vulgaris L.)
Authors: Matsuhira Hiroaki , Kitazaki Kazuyoshi , Matsui Katsunori , Kubota Keisi , Kuroda Yosuke , Kubo Tomohiko 
Published: June 2021

Abstract
The stability of cytoplasmic male sterility expression in several genetic backgrounds was investigated in sugar beet (Beta vulgaris L.). Nine genetically heterogenous plants from old cultivars were crossed with a cytoplasmic male-sterile line to obtain 266 F1 plants. Based on marker analysis using a multiallelic DNA marker linked to restorer-of-fertility 1 (Rf1), we divided the F1 plants into 15 genotypes. We evaluated the phenotypes of the F1 plants under two environmental conditions: greenhouse rooms with or without daytime heating during the flowering season. Three phenotypic groups appeared: those consistently expressing male sterility (MS), those consistently having restored pollen fertility, and those expressing MS in a thermo-sensitive manner. All plants in the consistently male-sterile group inherited a specific Rf1 marker type named p4. We tested the potential for thermo-induced male-sterile plants to serve as seed parents for hybrid seed production, and three genotypes were selected. Open pollination by a pollen parental line with a dominant trait of red-pigmented hypocotyls and leaf veins resulted in seed setting on thermo-induced male-sterile plants, indicating that their female organs were functional. More than 99.9% of the progeny expressed the red pigmentation trait; hence, highly pure hybrids were obtained. We determined the nucleotide sequences of Rf1 from the three genotypes: one had a novel allele and two had known alleles, of which one was reported to have been selected previously as a nonrestoring allele at a single US breeding station but not at other stations in the US, or in Europe or Japan, suggesting environmental sensitivity.
Platelet Rich Plasma-Derived Exosomal USP15 Promotes Cutaneous Wound Healing via Deubiquitinating EIF4A1
Authors: Xu Yan , Lin Ze , He Lei , Qu Yanzhen , Liu Ouyang , Han Yu , Xu Chao , Duan Deyu 
Published: June 2021

Abstract
Background: Epithelial regeneration is an essential wound healing process, and recent work suggests that different types of exosomes (Exos) can be employed to improve wound repair outcomes by promoting such epithelial regeneration. Platelet-rich plasma (PRP) is known to facilitate enhanced wound healing, yet the mechanisms underlying its activity are poorly understood. Results: We found that PRP-derived exosomes (PRP-Exos) effectively promoted the in vitro proliferation, migration, and wound healing activity of human immortalized keratinocytes (HaCaT cells). USP15 was further identified as a key mediator through which these PRP-Exos were able to promote tissue repair both in vitro and in vivo. At a mechanistic level, USP15 enhanced the functional properties of HaCaT cells by promoting EIF4A1 deubiquitination. Conclusions: PRP-Exos and USP15 represent promising tools that can promote wound healing via enhancing epithelial regeneration.
Problematic Khat Use Among Prisoners in Debre Berhan Prison, Ethiopia: A Cross-Sectional Study
Authors: Berhanu Kaleab , Haile Yohannes Gebreegziabhere , Limenhe Asnake , Habatmu Kassahun , Alem Atalay 
Published: June 2021

Abstract
Background

Cathine and cathinone which are the main psychostimulant components of khat, a green leaf chewed by many people in Yemen and East Africa for recreational purposes are controlled drugs by the UN, but khat chewing is legal in those countries. There are reports on the prevalence of khat use and its association with some health problems and alteration of behavior in communities of those countries. However, there is lack of evidence on the prevalence and associated factors of problematic khat use (PKU) among prisoners. This study aimed to assess the prevalence and associated factors of PKU among prisoners of Debre Berhan prison in Ethiopia.
Methods

A cross-sectional study was conducted to assess history of PKU among prisoners before imprisonment at Debre Berhan prison. Randomly selected 347 prisoners were interviewed using Drug Abuse Screening Test (DAST) to screen for PKU in May 2017. Data were entered using Epi-Data version 3.1 and analyzed using Stata version 13 software. Bivariate and multivariable binary logistic regressions were conducted. Crude odds ratio and adjusted odds ratio (AOR), with 95% confidence interval (CI), are reported. Variables with p-value of < 0.05 were reported to be significantly associated with PKU.
Results

About one-third (28.5%) of the prisoners had PKU before imprisonment. Factors significantly associated with increased odds of PKU included being non-Orthodox Christian in religion (AOR = 18.1; 95% CI= (3.8, 85.8)), infrequent visit to worship place irrespective of religion (AOR = 2.9; 95% CI= (1.1, 7.9)), being urban resident (AOR = 22.0; 95% CI= (7.7, 62.9)), perception that the current offence is related to using the substance (AOR = 6.0; 95% CI= (2.8, 12.8)), family history of substance use (AOR = 4.1; 95% CI= (1.2, 14.6)), and living alone before imprisonment (AOR = 3.55; 95% CI= (1.2, 10.7)). Whereas, being married was significantly associated with lower odds of PKU (AOR = 0.3; 95% CI= (0.0, 0.8)).
Conclusion

Higher prevalence of PKU before imprisonment is reported in this population. In addition to other socio-demographic factors that showed association with use of the substance, current offence that led to imprisonment was also perceived as related to PKU. To prevent crime and health-related consequences of PKU in the community integrated action is recommended.
Decreased eGFR predicts long-term recurrence after catheter ablation of atrial fibrillation
Authors: Zheng Jing , Zu De-ling , Cheng Ke-yun , Xia Yun-long , Dong Ying-xue , Gao Zhen-yan 
Published: June 2021

Abstract
Background: Catheter ablation is an established therapy for atrial fibrillation (AF), but recurrence after ablation is still a great challenge. A higher prevalence of AF has been reported among patients with chronic renal disease. However, little is known about the effect of renal function on the efficiency of AF ablation. This study aimed to evaluate the effect of renal function on the prognosis of catheter ablation for AF. Methods: A total of 306 consecutive drug-refractory symptomatic patients with AF who underwent first-time catheter ablation were enrolled in the present study. The individuals underwent circumferential pulmonary vein isolation for paroxysmal AF and stepwise ablation for persistent AF. Results: Following up 27.2 ± 19.5 months after a single procedure, 202 patients (66.01%) were free of atrial tachyarrhythmia (non-recurrence group), and the other 104 patients experienced recurrence (recurrence group). The recurrence group had a larger left atrial diameter (LAD) and left atrial volume (LAV), a higher LAV index (LAVI) (p < 0.01, respectively), and a lower estimated glomerular filtration rate (eGFR) (53.5 ± 14.4 vs. 65.5 ± 13.3 ml/min/1.732, p < 0.001) and creatinine clearance rate (CCr) (85.2 ± 26.1 vs. 101.5 ± 29.4 ml/min, p < 0.05). Multivariate logistic analysis indicated eGFR and LAVI as independent predictors of long-term recurrence after single catheter ablation. Conclusion: Decreased eGFR and elevated LAVI may facilitate the long-term recurrence of atrial tachyarrhythmia after catheter ablation for AF.
Application of Fusion-Fluorescence Imaging Using Indocyanine Green in Endoscopic Endonasal Surgery: Preliminary Data
Authors: Lee Min Ho , Lee Tae-Kyu 
Published: June 2021

Abstract
PurposeIndocyanine green (ICG) has been used in endoscopic surgery in the neurosurgical field, but it has been challenging to determine the associated efficiency due to limitations with visualization in the previous endoscopic system. A new endoscopic system was recently introduced; therefore, we summarize our experiences with the application and integration of the system.MethodsFrom March to May 2021, a newly introduced endoscopic system was used in 6 patients. (3 pituitary adenomas, 1 pituitary apoplexy, 2 tuberculum sellae meningiomas) and 12.5 mg of ICG was injected for each study.ResultsThree pituitary adenomas, including one acromegaly, were well identified with ICG. However, one pituitary apoplexy and two meningiomas were not visualized with ICG. Meanwhile, ICG appeared to be effective for determining the viability of nasoseptal mucosa.ConclusionICG provides real-time information during endoscopic endonasal surgery. We suggest that the pituitary adenoma can be stained with an ICG using the fusion-fluorescence imaging endoscopic system. This approach will enhance the surgeon’s ability to achieve gross total resection.