bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retrospective Study of Genetic Diversity of Acinetobacter Baumannii-Resistant Strains Isolated from Patients in Rīga East University Hospital in Latvia
Authors: Liepiņš Māris , Krūmiņa Angelika , Meistere Irēna , Kosjkina Diāna , Ķibilds Juris , Valciņa Olga , Lejnieks Aivars 
Published: May 2021

Abstract
Acinetobacter baumannii is an aerobic gram-negative opportunistic bacterial pathogen, an emerging cause of healthcare-associated infections, associated with increased morbidity, mortality and healthcare costs. It has been widely found in the hospital environment, exhibiting high resistance to antimicrobials, affecting the spread of healthcare-associated infections and preventing effective infection control. The role of virulence factors in the pathogenesis of A. baumannii related human infections remains unclear. Therefore, molecular testing of pathogenic bacteria is an important tool for improving infection control measures against A. baumannii with combined resistance. The aim of this study was to analyse A. baumannii infection cases, antimicrobial resistance profiles and to characterise the genetic heterogeneity of isolates. In general, outbreaks occurring in hospitals are presumed to be clonal, with patient-to-patient transmission of essentially identical strains. Treatment decisions are based on a combination of in vitro susceptibility assays and empirical results based on patient outcomes.
On a Trajectory for Success—9 in Every 10 People With a Degenerative Meniscus Tear Have Improved Knee Function Within 2 Years After Treatment: A Secondary Exploratory Analysis of a Randomized Controlled Trial
Authors: Berg Bjørnar , Roos Ewa M. , Kise Nina Jullum , Engebretsen Lars , Holm Inger , Risberg May Arna 
Published: May 2021

Objective To identify trajectories of patient-reported knee function over 5 years in patients with degenerative meniscal tears, and to explore whether baseline characteristics were associated with trajectories of sport and recreational function. Design Prospective cohort study. Methods We conducted a secondary exploratory analysis of the Odense-Oslo Meniscectomy Versus Exercise randomized controlled trial. Patient-reported knee function was assessed with the Knee injury and Osteoarthritis Outcome Score (KOOS) at baseline, 3 months, 1 year, 2 years, and 5 years. We used group-based trajectory modeling to identify subgroups of patients who followed distinctive patterns of change. Multinomial logistic regression was used to examine the associations of patient demographics, knee function, and disease-related factors with KOOS sport and recreational function subscale trajectories. Results The analysis of data from a sample of 140 participants identified 3 trajectories for all KOOS subscales: (1) low, minimal improvement (10%-12% of the participants), (2) moderate, gradual improvement (20%-36%), and (3) high, early improvement (53%-70%). Baseline prognostic factors for deteriorating function in sport and recreational activities were higher body mass index, poorer mental health, greater knee pain, lower perceived knee function, poorer quadriceps and hamstrings muscle strength, poorer functional performance, more meniscal extrusion, and radiographic signs of knee osteoarthritis. Conclusion We found 3 distinct trajectories of patient-reported knee function over 5 years: (1) low, minimal improvement, (2) moderate, gradual improvement, and (3) high, early improvement. Nine in every 10 participants improved at least gradually over 2 years after diagnosis of a degenerative meniscal tear. J Orthop Sports Phys Ther 2021;51(6):289–297. Epub 10 May 2021. doi:10.2519/jospt.2021.10025
Latent Class Analysis to Predict Outcomes of Early High-Intensity Physical Therapy After Total Knee Arthroplasty, Based on Longitudinal Trajectories of Walking Speed
Authors: Dandis Rana , Westeneng Jacco M. , Inthout Joanna , Nijhuis-Van der Sanden Maria W.G. , Harmelink Karen E. , Teerenstra Steven , Hoogeboom Thomas J. 
Published: May 2021

Objective To (1) classify patients who are recovering from total knee arthroplasty (TKA) based on walking speed during an early physical therapy program, and (2) assess whether walking-speed trajectory predicts performance on the timed up-and-go (TUG) test. Design Cohort study. Methods We included 218 patients from a 10-day physical therapy program after TKA. A latent class mixed model was used to classify patients according to their walking-speed trajectory during the program. We assessed the change in TUG test score from pre-TKA to 6 weeks and 1 year after TKA. The association between change in TUG test score and walking-speed trajectory was assessed using multivariable regression. Results There were 2 groups with distinct walking-speed trajectories: a high-gain group (46%) and a low-gain group (54%). There was no significant association between change in TUG test score and walking-speed trajectory after TKA and physical therapy. Function (based on TUG test performance) improved for all patients 1 year after TKA, irrespective of walking-speed trajectory (ie, high or low gain) early in postoperative physical therapy. Conclusion Although we distinguished different groups based on functional outcomes during physical therapy, the clinical relevance of classifying patients based on walking speed remains unclear, as it did not predict short- and long-term functional outcomes. J Orthop Sports Phys Ther 2021;51(7):362–371. Epub 10 May 2021. doi:10.2519/jospt.2021.10299
Exploring Integrated Care for Musculoskeletal and Chronic Health Conditions
Authors: Gleadhill Connor , Kamper Steven J. , Lee Hopin , Williams Christopher M. 
Published: May 2021

Synopsis Integrated care is a continuum of services delivered by a system organized around the health needs of people rather than diseases. People with chronic musculoskeletal pain often live with coexisting chronic health conditions. Current care for musculoskeletal pain remains narrowly focused on individual painful conditions, despite the complex health needs of patients. We explore the challenges of delivering integrated care to people with musculoskeletal pain and coexisting chronic health conditions. We discuss these challenges in relation to 3 areas: (1) the relationships between musculoskeletal conditions and other chronic health conditions, (2) the factors that impact the clinician's capacity to provide integrated care for musculoskeletal conditions, and (3) system-level constraints that impact both the clinician's delivery of care and the patient's health care experience. We suggest ways by which clinicians and researchers may move toward better integrated care for musculoskeletal pain and coexisting chronic health conditions. J Orthop Sports Phys Ther 2021;51(6):264–268. doi:10.2519/jospt.2021.10428
Recent Injury, Severe Radiographic Change, and Lower Quadriceps Strength Increase Risk of Knee Pain Exacerbation During Walking: A Within-Person Knee-Matched Study
Authors: Liu Qiang , Li Zhikun , Ferreira Manuela , Wise Barton , Hunter David J. , Tao Ke , Lin Jianhao , Zhang Yuqing 
Published: May 2021

Objective To examine the associations of knee injury, radiographic osteoarthritis severity, and quadriceps strength with knee pain exacerbation during walking. Design Within-person knee-matched case-control study. Methods Participants from the Osteoarthritis Initiative who completed a 20-m walking test at the 24-month visit were included. Pain exacerbation was defined as an increase in pain intensity of 1 or more on a numeric rating scale (0 as no pain and 10 as the worst imaginable pain) while completing the 20-m walking test. We used conditional logistic regression to assess the relation of recent knee injury, Kellgren-Lawrence (KL) grade, and quadriceps strength to unilateral knee pain exacerbation during walking. Results We included 277 people who experienced unilateral knee pain exacerbation during the walking test. Recent knee injury was associated with pain exacerbation during walking, with an odds ratio of 3.4 (95% confidence interval [CI]: 1.3, 9.2). Compared with knees with a KL grade of 0, the odds ratios of pain exacerbation during walking were 1.3 (95% CI: 0.7, 2.7), 3.3 (95% CI: 1.5, 7.1), and 8.1 (95% CI: 3.1, 21.1) for knees with KL grades of 2, 3, and 4, respectively. Painful knees with a deficit in quadriceps strength of greater than or equal to 4% had a 1.4-fold (95% CI: 1.0, 1.9) higher risk of pain exacerbation during walking than their pain-free counterparts. Conclusion Recent knee injury, more severe radiographic osteoarthritis, and lower quadriceps strength were associated with an increased risk of knee pain exacerbation during walking. J Orthop Sports Phys Ther 2021;51(6):298–304. Epub 10 May 2021. doi:10.2519/jospt.2021.9735
Role Comparison between Deep Belief Neural Network and NeuroEvolution of Augmenting Topologies to Detect Diabetes
Authors: Wijaya A.B.M. , Ikawahyuni D.S. , Gea Rospita , Maedjaja Febe 
Published: May 2021

Diabetes in Indonesia has been perceived as a grave health problem and has been a concern since the early 1980â€™s [2]. The prevalence of diabetes in adults in Indonesia, as stated by IDF, was 6.2% with the total case amounting to 10.681.400. Moreover, Indonesia is also in the top ten global countries with the highest diabetes case in 2013. This research will investigate the role of Deep Belief Network (DBN) and NeuroEvolution of Augmenting Topology (NEAT) in solving regression problems in detecting diabetes. DBN works by processing the data in unsupervised network architectures. The algorithm puts Restricted Boltzmann Machines (RBM) into a stacked process. The output of the first RBM will be the input for the next RBM. On the other hand, the NEAT algorithm works by investigating the neural network architecture and evaluating the architecture using a multi-layer perceptron algorithm. Collaboration with a Genetic Algorithm in NEAT is the key process in architecture development. The research results showed thatÂ DBN could be utilized as the initial weight for Backpropagation Neural Network at 22.61% on average. On the other hand, the NEAT algorithm could be used by collaborating with a multi-layer perceptron to solve this regression problem by providing 74.5% confidence. This work also reveals potential works in the future by combining the Backpropagation algorithm with NEAT as an evaluation function and by combining it with DBN algorithms to process the produced initial weight.
To the question of lexical and semantic characteristics of fiction text
(based on material of H.P. Lovecraft’s work «The Outsider»)
Authors: Busyga Ivan Vadimovich , Babak Oleg Valentinovich 
Published: May 2021

The research is devoted to the identification of lexical and semantic relations and the establishment of similarities and differences of H.P. Lovecraft’s work «The Outsider» in English and Russian. A comprehensive analysis of the studied words and phrases was done. In the present work, the methods of comparative and statistical analysis which allowed to identify discrepancies between the English and Russian versions of words and phrases were used.
ANALISIS JUMLAH MUATAN LISTRIK SERTA ENERGI PADA KAPASITOR BERDASARKAN KONSTANTA DIELEKTRIK SUATU MATERIAL
Authors: Siagian Sinta Marito , Jaya Gede Wiratma , Nurhidayati Indah 
Published: May 2021

ABSTRAKPenelitian ini dilakukan untuk mengetahui nilai muatan listrik, nilai kapasitor yang dirangkai secara seri dan paralel kemudian nilai energi yang tersimpan pada kapasitor berdasarkan jenis-jenis material dengan konstanta dielektrik yang telah ditentukan. Metode yang dilakukan adalah mengkaji masing-masing nilai tersebut berdasarkan konstanta dielektrik dengan perhitungan matematis berbantuan Microsoft excel untuk menghasilkan grafiknya. Adapun tegangan yang digunakan pada metode ini adalah 20, 40, 60 dan 100 volt dan material yang dianalisis antara lain kaca, udara, mika, kertas dan polystiren. Analisis dilakukan menggunakan analisis kuantitatif yang memanfaatkan data berupa angka yang dipresentasikan melalui grafik. Ditemukan hasil perhitungan matematis bahwa kaca memiliki jumlah muatan yang lebih besar dibandingkan dengan material yang lainnya. pada saat dirangkaiakan secara seri dan paralel diperoleh bahwa jumlah muatan kapasitor yang dirangkaiakan secara paralel jauh lebih besar dibandingkan seri, energi yang tersimpan pada kapasitor yang dirangkaikan secara paralel juga memiliki nilai yang besar dari pada kapasitor yang dirangkai secara seri. Kata kunci: kapasitor; konstata dielektrik; tegangan. ABSTRACTThis research aims are to analyze the value of the electric charge, the value of the capacitor connected in series and paralel then the energy value stored in the capacitor based on the types of materials with determined a dielectric constant. The method used to examine each of these values based on the dielectric constant with mathematical calculations assisted by Microsoft Excel to produce the graph. The voltages used on this methode are 20, 40, 60, and 100. The analysis using quantitative analysis that utilizes data in the form of numbers presented through graphs. It has been studied based on the physical formulation of the value of an electric charge against the dielectric constant of glass, air, mica, paper and polystyrene. It was found that the results of mathematical calculations show that glass has a greater amount of charge compared to other materials. When assembled in series and paralel, it is found that the amount of charge on the capacitor connected in paralel is much greater than in series, the energy stored in the capacitor connected in paralel also has a greater value than the capacitor connected in series. Keywords: capasitor; dielectric constant; voltage.
Temperature effect on mechanical and tribological properties of WNiCoFe alloy powder for cutting tools
Authors: Ge Xinfeng 
Published: May 2021

In order to improve the wear resistance of WNiCoFe alloy for cutting tools, WNiCoFe alloy powder is prepared by multiple metals electrolysis, alloy powder and its sintered morphology is observed and phase is analyzed using X-ray diffractometer and scanning electron microscope (SEM), the effect of sintering temperature on its physical mechanics and friction properties was studied. The results show that the prepared WNiCoFe alloy powder is alloyed to some extent, irregular and finer particle size, the diffraction peaks of Co3Fe7 and Fe19Ni are formed in addition to the elemental Fe; the maximum hardness of the sintered is 107.6HRB, the maximum bending strength at three points is 1638.3 mpa, the maximum density is 96.2%, and wear loss is 0.498–0.555 g when WNiCoFe alloy powder is sintered at 800∘C. Diamond tools are made with WNiCoFe alloy powder as the main matrix composition, and cut hard stone, cutting velocity is 8.6 m2/h and life is 11.3 m2/m, which has a good comprehensive performance.
Thigh and Leg Muscle MRI Findings in GNE Myopathy
Authors: Fatehi Farzad , Advani Soroor , Okhovat Ali Asghar , Ziaadini Bentolhoda , Shamshiri Hosein , Nafissi Shahriar 
Published: May 2021

Background: Muscle MRI protocols have been developed to assess muscle involvement in a wide variety of muscular dystrophies. Different muscular dystrophies can involve muscle groups in characteristic patterns. These patterns can be identified in muscle MRI in the form of fatty infiltration. Objective: This study was conducted to add the existing knowledge of muscle MRI in GNE myopathy and evaluate the correlation of muscular involvement with different gene mutations. Methods: The MRI scans of the 18 GNE patients were analyzed retrospectively. Cluster analysis was done for grouping the muscles and patients. Results: The four muscles with the highest fat infiltration were adductor magnus, tibialis anterior, semitendinosus, and semimembranosus. Furthermore, three clusters of muscle involvement were found, including cluster 1, typical muscle involvement indicating muscles with the highest infiltration: extensor digitorum longus, gracilis, biceps femoris, soleus, gastrocnemius medial, adductor longus, tibialis anterior, adductor magnus, semimembranosus, semitendinosus; cluster 2, less typical muscle involvement indicating muscles with intermediate fat infiltration, peroneus longus, gastrocnemius lateral, and minimal fat infiltration in most of the patients, i.e., tibialis posterior; and cluster 3, atypical muscle involvement with low-fat infiltration: rectus femoris, sartorius, vastus intermedius, vastus medialis, and vastus lateralis. Conclusions: This study found three clusters of muscle involvement and three groups of patients among GNE patients. Hamstring muscles and the anterior compartment of the lower leg were the muscles with the highest fat infiltration. Moreover, a weak genotype-muscle MRI association was found in which tibialis posterior was more involved in patients with the most frequent mutation, i.e., C.2228T > C (p.M743T) mutation; however, this finding may be related to longer disease duration.
Twitter as a Tool to Spread Communication Regarding Genitourinary Cancers During the COVID-19 Pandemic
Authors: Salgia Sabrina , Salgia Nicholas , Prajapati Sweta , Seghal Ishaan , Bautista Frank , Ruel Nora , Salgia Meghan , Salgia Deborah A. , Salgia Ravi , Pal Sumanta K. 
Published: May 2021

OBJECTIVES: To better characterize the relay of information about prostate, kidney, and bladder cancer on Twitter in relation to the COVID-19 pandemic. MATERIALS AND METHODS: Tweets containing the joint hashtags “#COVID-19” and either “#bladder cancer”, “#kidney cancer”, or “#prostate cancer” were identified on the Twitter platform from January 1, 2020 to July 30, 2020. The Twitter handle responsible for each tweet was categorized as an Academic, Medical Education, Patient Advocacy Groups/Non-Profits, Pharmaceutical, or Other entity based on content domain. Descriptive statistics were used to summarize data on Twitter handle characteristics stratified by disease category (bladder, kidney, and prostate). Median/interquartile range and percentages were used to summarize continuous and categorical data, respectively. Number of tweets containing the relevant joint hashtags were tracked over time in relation to the cumulative United States case count of COVID-19. RESULTS: The content of 730 total tweets containing the joint hashtags “COVID-19” and either “#bladder cancer” (138 tweets), “#kidney cancer” (137 tweets), or “#prostate cancer” (455 tweets) from January 1, 2020 to July 31, 2020 were analyzed. We identified 326 unique Twitter handles across all disease states (62 bladder, 47 kidney, and 217 prostate-related). Academic Twitter handles accounted for the greatest number of tweets containing the joint hashtags (31%). Temporal tracking of tweets with regard to monthly U.S. COVID cases revealed that communication surged in March of 2020 and peaked in April for both bladder and kidney cancer, whereas related prostate cancer Twitter communication peaked in May of 2020. CONCLUSIONS: As COVID-19 case counts rose in the United States initially, so too did communication surrounding COVID-19 and genitourinary cancers on Twitter. Many of these conversations were driven by academically-associated Twitter accounts.
Protective effect of caffeine and/or taurine on the 6-hydroxydopamine-induced rat model of Parkinson’s disease: Behavioral and neurochemical evidence
Authors: Abuirmeileh Amjad N. , Abuhamdah Sawsan M. , Ashraf Asser , Alzoubi Karem H. 
Published: May 2021

Background: Caffeine and taurine, which possess neuro-modulatory activity happen to be consumed together as part of the constituents of energy drinks, could have beneficial effects and prevent neuronal deterioration in Parkinson’s disease (PD). Objective: This study aimed to investigate behavioral and neurochemical effects of these two agents in an animal model of PD at two time points to evaluate possible neuro-protective or neuro-modulatory effects. Methods: Stereotaxic injection of 6-hydroxydopamine (6-OHDA) in rat striatum was used to model PD-like behavior in animals. Motor behavior was assessed by a characteristic rotation behavior response to the apomorphine challenge and dopamine levels in the striatum were quantified using HPLC-ED. Results: A reduction in apomorphine induced rotations following administration of caffeine and/or taurine as compared to the untreated lesioned group (controls) was shown. Significant decreases in dopamine levels were also seen in the ipsilateral side of 6-OHDA group, this effect was not significantly reversed in caffeine and taurine treated groups. Treatments partially restored the content of DA levels in the lesioned striatum. Conclusions: Current results demonstrated beneficial effects for the combination of caffeine and taurine in PD animal model, suggesting that consumption of both agents could be a new added therapeutic target for Parkinson’s disease prevention and treatment.
KREATIVITAS RAHAYU SUPANGGAH PADA FILM OPERA JAWA KARYA GARIN NUGROHO
Authors: Salim Muhammad Nur 
Published: May 2021

ABSTRACT One of the developments in film in Indonesia is the musical genre film. This genre film experienced a post-reform high point when Sherina's Adventure Film came. This point then became the beginning of the development of musical genre films that were born in the 2000s period. One of the interesting musical films is the Javanese Opera Film by Garin Nugroho. Opera Jawa is interesting because first, Opera Jawa has received various awards and nominations at both national and international levels. Second, because this film bases its musical work on Javanese gamelan or gamelan media. This second reason is the focus of this research. The research "Rahayu Suanggah's Creativity in Garin Nugroho's Javanese Opera Film" is an attempt to reveal one of the film music creation methodologies based on her creative process with Javanese karawitan media (gamelan music). The musical concepts of the musical that were carried by Rahayu Supanggah as the music director was revealed through Rahayu Supanggah's conceptual approach in Bothekan Karawitan Garap's book (2007). The results of this study; Rahayu Supanggah uses Javanese musical nuances in composing Javanese Opera music by involving songs that are composed in various variations such as; 1) single tembang, 2) pathetan, 3) nothing, 4) palaran, and 5) arrangement of traditional pieces while the illustration music consists of 1) New Composition, 2) Illustration of Traditional Music, 3) Exploration Music. Keywords: Creativity, Music, Javanese Opera, Rahayu Supanggah ABSTRAK Perkembangan film di Indonesia salah satunya pernah diwarnai oleh film genre musikal. Film genre ini mengalami titik puncak pasca reformasi ketika Film Petualangan Sherina hadir. Titik tersebut kemudian menjadi awal perkembangan film genre musikal yang lahir pada periode tahun 2000-an. Salah satu film musikal yang menarik adalah Film Opera Jawa karya Garin Nugroho. Opera Jawa menarik karena pertama, Opera Jawa mendapatkan berbagai penghargaan dan nominasi tingkat nasional maupun internasional. Kedua, karena film ini mendasarkan garapan musikalnya dengan media gamelan Jawa atau karawitan. Alasan kedua inilah yang menjadi fokus pada penelitian ini.Penelitian “Kreativitas Rahayu Suanggah dalam Film Opera Jawa Karya Garin Nugroho” merupakan upaya mengungkap salah satu metodologi penciptaan musik film yang mendasarkan proses kreatifnya dengan media karawitan Jawa (musik gamelan). Konsep-konsep musikal karawitan yang diusung Rahayu Supanggah sebagai music director diungkap melalui pendekatan konsep garap-nya Rahayu Supanggah dalam buku Bothekan Karawitan Garap (2007). Hasil penelitian ini; Rahayu Supanggah menggunakan nuansa karawitan Jawa dalam menggarap musik Opera Jawa dengan melibatkan tembang yang digarap dalam berbagai variasi seperti; 1) tembang tunggal, 2) pathetan, 3) ada-ada, 4) palaran dan 5) aransemen gendhing tradisi sedangkan musik ilustrasi terdiri dari 1) Komposisi Baru, 2) Ilustrasi Gending Tradisi, 3) Musik Eksplorasi.Kata Kunci: Kreativitas, Musik, Opera Jawa, Rahayu Supanggah