bluuebunny/crossref_metadata_2025_split huggingface dataset:
Microalgae cultivation in wastewater effluent from tilapia culture pond for enhanced bioethanol production
Authors: Bhuyar Prakash , Trejo Marlen , Dussadee Natthawud , Unpaprom Yuwalee , Ramaraj Rameshprabu , Whangchai Kanda 
Published: May 2021

Abstract
The large number of wastewaters are generated because of the various production processes. Vegetable and fish processing can be considered an important industry for wastewater generation. The essential method for completing this waste is to digest the organic matter using anaerobic digestion followed by aerobic wastewater treatment processes; however, wastewater from tilapia culture pond retains considerable quantities of inorganic substances, particularly nutrients like nitrogen and phosphorus. The optimal conditions for cultivating Chlorella vulgaris from wastewater treatment effluent from tilapia culture pond were investigated in this study. The appropriate conditions were found to be 10% initial stock suspension, 20 cm depth, and 12 days of culture conditions. C. vulgaris had an optical density of 0.649, a cell density of 17.68 × 105 cells/mL, and biomass of 0.376 ± 94.21 mg/L after cultivation. Discharged wastewater from the fishpond was utilized for the improved growth of microalgae and obtained biomass was used for bioethanol production. This study verified that fishpond wastewater is the best source of nutrients for algal mass production and biofuel applications.
Step economy in the Stereoselective Synthesis of Functionalized Oxindoles via Organocatalytic Domino/One-pot Reactions
Authors: Bortolami Martina , Leonelli Francesca , Feroci Marta , Vetica Fabrizio 
Published: May 2021

:
Oxindoles are an important class of heterocyclic scaffolds widely present in natural products and bioactive compounds. For this reason, a plethora of methodologies for the stereoselective synthesis of enantioenriched oxindoles has been studied over the years. Among all the reported synthetic strategies, organocatalysis has proven to be a powerful tool for the asymmetric synthesis of this class of compounds being a step- and atom-economical, environmentally friendly, and non-toxic approach. This review will outline the application of asymmetric organocatalysis in the synthesis of chiral oxindole-based structures, relying on domino/one-pot reaction sequences in a step-economical fashion.
Differences Among Sexes in Blood Pressure: A Combinatorial Consequence
of the Differences between RAAS Components, Sex Hormones,
and Time Course
Authors: Yang Xiaomei , Liu Shien , Zhang Zhongming 
Published: May 2021

:
For all lives regardless of sex, the longitudinal increase in blood pressure (BP) with age
is attributed to lifestyle, internal environments like systemic brain-derived neurotrophic factor (BDNF)
signaling, and external environments, allowing the individuals to better adapt to the developmental
and environmental changes. Basic levels of renin-angiotensin-aldosterone system (RAAS)
components in males and females define the fundamental sex difference in BP, which may be set
by prenatal programming and the profound influence of BP after birth. The innate sex difference in
BP is magnified during puberty growth and later on, affected and modified by menopause in women.
At the age of 70 and older, blood pressure has been found to be similar for men and women. Understanding
the prenatal setup and development of sexual dimorphism in BP may provide preventative
therapeutic strategies, including timing and choice of drugs, for individuals with abnormal BP.
Experimental Investigation of Shear Strength for Steel Fibre Reinforced Concrete Beams
Authors: Demakos Constantinos B. , Repapis Constantinos C. , Drivas Dimitros P. 
Published: May 2021

Aims:The aim of this paper is to investigate the influence of the volume fraction of fibres, the depth of the beam and the shear span-to-depth ratio on the shear strength of steel fibre reinforced concrete beams.Background:Concrete is a material widely used in structures, as it has high compressive strength and stiffness with low cost manufacturing. However, it presents low tensile strength and ductility. Therefore, through years various materials have been embedded inside it to improve its properties, one of which is steel fibres. Steel fibre reinforced concrete presents improved flexural, tensile, shear and torsional strength and post-cracking ductility.Objective:A better understanding of the shear performance of SFRC could lead to improved behaviour and higher safety of structures subject to high shear forces. Therefore, the influence of steel fibres on shear strength of reinforced concrete beams without transverse reinforcement is experimentally investigated.Methods:Eighteen concrete beams were constructed for this purpose and tested under monotonic four-point bending, six of which were made of plain concrete and twelve of SFRC. Two different aspect ratios of beams, steel fibres volume fractions and shear span-to-depth ratios were selected.Results:During the experimental tests, the ultimate loading, deformation at the mid-span, propagation of cracks and failure mode were detected. From the tests, it was shown that SFRC beams with high volume fractions of fibres exhibited an increased shear capacity.Conclusion:The addition of steel fibres resulted in a slight increase of the compressive strength and a significant increase in the tensile strength of concrete and shear resistance capacity of the beam. Moreover, these beams exhibit a more ductile behaviour. Empirical relations predicting the shear strength capacity of fibre reinforced concrete beams were revised and applied successfully to verify the experimental results obtained in this study.
Experience of Peer Bloggers Using a Social Media Website for Adolescents With Depression or Anxiety: Proof-of-Concept Study
Authors: Karim Sana , Hsiung Kimberly , Symonds Maria , Radovic Ana 
Published: May 2021

Background
Supporting Our Valued Adolescents (SOVA) is a moderated and anonymous social media website intervention. SOVA ambassadors are adolescents and young adults (AYA) asked to write monthly blog posts and comments on others’ posts on topics surrounding mental health.

Objective
This study aims to understand the feasibility and acceptability of peer blogging for a moderated mental health intervention website and explore whether bloggers—AYA who self-report symptoms of depression and anxiety—experience potential benefits.

Methods
AYA aged 14 to 26 years with a self-reported history of depression or anxiety were recruited to the SOVA Peer Ambassador Program. Participants were asked to write one blog post a month and comment at least four times a month on other blog posts, for which they were compensated for up to US $15 monthly. Outcome variables measured at baseline and 3 months after intervention included website usability and feasibility, depressive symptoms, anxiety symptoms, mental health treatment history, cybercoping, personal blogging style, self-esteem, loneliness, mental health stigma, social support, and positive youth development characteristics. Open-ended questions were asked about their blogging acceptability and usability.

Results
Of 66 AYA showing interest and completing onboarding, 71% (47/66) wrote at least one blog post, with an average of 3 posts per person. A sample of 51% (34/66) of participants completed a 3-month survey for the full analysis. Almost all 34 participants were satisfied with the experience of blogging (32/34, 94%) and rated the website usability as good (80.1, SD 14.9). At 3 months, self-esteem scores increased by 2.1, with a small-medium effect size (P=.01; Cohen d=0.45), and youth competence and confidence increased by 0.7 (P=.002) and 1.3 (P=.002), with medium effect sizes (Cohen d=0.62 and 0.60), respectively.

Conclusions
A blogging intervention for AYA with a history of depression or anxiety was feasible with regular and active engagement and shows evidence in a one-sample design for positive changes in strength-based assets—self-esteem, competence, and confidence—which map onto resilience.
Studi Docking Molekuler Senyawa Dalam Minyak Atsiri Pala (Myristica fragrans H.) Dan Senyawa Turunan Miristisin Terhadap Target Terapi Kanker Kulit
Authors: Pratama Alfian Bagas , Herowati Rina , Ansory Hery Muhamad 
Published: May 2021

Kanker kulit adalah penyakit di mana kulit kehilangan kemampuannya untuk regenerasi dan tumbuh secara normal. Penyebab umum terjadinya kanker kulit adalah intesitas paparan sinar UVB. Penelitian terdahulu telah membuktikan kandungan senyawa di dalam minyak atsiri pala (Myristica fragrans H.) khususnya miri stsin memiliki khasiat sebagai antioksidan dan efek cytotoxic. Telah dilakukan skrining target molekuler dari kandungan kimia minyak atsiri pala beserta turunan miristisin-nya terhadap target molekuler antikanker kulit antara lain Heat Shock Protein 90 (HSP90A), Prostaglandin Synthase 2 (PTGS2) dan Dihydroorotate Dehidrogenase (DHODH), dan memprediksi interaksi senyawa dari ke 61 ligan uji dengan target molekuler tersebut, kemudian dilakukan docking molekuler menggunakan perangkat lunak PyRx 0.8. Hasil penelitian menunjukkan bahwa senyawa dalam minyak atsiri pala yaitu Guanicin memiliki nilai ΔGbind yang baik pada HSP90A dengan nilai -8,2 kkal/mol. Hasil docking antara protein PTGS2 dan DHODH dengan ligan baik dari senyawa dalam minyak atsiri pala maupun senyawa turunan miristisin menunjukkan bahwa hampir semua ligan dapat berinteraksi dengan kedua target dengan ligan yang nilai ΔGbind paling kecil dan memiliki model interaksi terbaik dari senyawa minyak atisi pala adalah asam dihidroguaiaretik, dengan nilai ΔGbind secara berurut-urut sebesar -8,1 kkal/mol dan -9,3 kkal/mol.
Rasionalitas Pendosisan Ketorolak pada Pasien Geriatri Dengan Penurunan Fungsi Ginjal Rawat Inap di RSUD Benyamin Guluh Kabupaten Kolaka Sulawesi Tenggara
Authors: Saputro Syaifullah , Wahyono Djoko , Yasin Nanang Munif 
Published: May 2021

Ketorolak merupakan NSAID yang utamanya dieliminasi melalui ginjal yang membutuhkan penyesuaian dosis pada pasien geriatri dengan penurunan fungsi ginjal. Penelitian ini bertujuan untuk mengetahui profil rasionalitas pendosisan ketorolak, menganalisis hubungan antara rasionalitas pendosisan dengan efektivitas terapi serta kejadian efek samping pada pasien geriatri rawat inap dengan penurunan fungsi ginjal. Penelitian dilakukan dengan rancangan cross-sectional. Pengambilan data secara retrospektif melalui penelusuran rekam medis pasien geriatri rawat inap RSUD Benyamin Guluh periode 2015-2020. Data yang diamati berupa regimen pengobatan, serum kreatinin, efektivitas terapi dan efek samping. Rasionalitas pendosisan dinilai berdasarkan kesesuaian dosis dengan referensi/formula Guisti Hayton. Efektivitas terapi tercapai jika penurunan VAS <50% dan kejadian efek samping dapat diamati pada catatan perkembangan pasien pada rekam medis. Uji statistik Chi Square dilakukan untuk mengetahui hubungan antara rasionalitas pendosisan dengan efektivitas terapi dan efek samping. Dari 100 kasus sebanyak 35 kasus mendapatkan pendosisan yang rasional dan 65 kasus pengobatan yang tidak rasional. Pendosisan rasional dengan efektivitas tercapai sebesar 85.7% dan tidak tercapai 14.3%, pendosisan tidak rasional dengan efektivitas tercapai sebesar 83.1% dan tidak tercapai sebesar 16.9%. Sedangkan efek samping tidak ditemukan pada kelompok rasional ataupun tidak rasional. Tidak terdapat hubungan yang signifikan antara rasionalitas dosis dengan efektivitas (p>0,05) maupun kejadian efek samping.
Representações da Mãe-África nas poesias moçambicana e afro-brasileira
Authors: Santos Donizeth 
Published: May 2021

Através da análise dos poemas “Sangue negro”, da poeta moçambicana Noémia de Sousa, “Regressão” e “Elo”, do poeta afro-brasileiro Oliveira Silveira, o artigo mostra que a Mãe-África é representada na poesia moçambicana como a mãe negra biológica, a nação, e o continente africano, enquanto que na afro-brasileira, além de ser a progenitora da raça negra, o continente africano é também a terra prometida, o paraíso perdido.
"Candid camera?" (Da presença e usos do fotográfico em alguma poesia portuguesa contemporânea)
Authors: Pereira Paulo Alexandre 
Published: May 2021

No presente artigo, examina-se a presença e funcionalidade do paradigma fotográfico em alguma poesia portuguesa contemporânea, procurando-se ilustrar a diversidade das suas incidências ideotemáticas e das estratégias de composição poética que com ele se conexionam.
Revisitações poéticas e pictóricas da Ilha de Moçambique
Authors: Secco Carmen Lucia Tindó 
Published: May 2021

A reescrita de Moçambique com a pena da poesia e as tintas dos afetos. Paisagens: poesia, pintura e história. O entrecruzamento de povos, culturas e saberes no chão moçambicano de heranças múltiplas.
The Effects of Perceived Leader Emotional Intelligence and Group Prototypicality on Subordinate Whistleblowing Intentions
Authors: Geng Xin 
Published: May 2021

ABSTRACT
While prior research has examined the impact of ethical leadership on subordinates' whistleblowing intentions, a leader's specific characteristics, such as emotional intelligence and group prototypicality, are underexplored. As with leadership style, they can play an important role in creating a control environment that facilitates fraud prevention, detection, and deterrence. This study examines the effects of perceived leader emotional intelligence and group prototypicality on the subordinate's intention to blow the whistle to the leader. Results indicate that a subordinate is more likely to blow the whistle when the leader is perceived as having high emotional intelligence or group prototypicality. Both relationships are mediated by the subordinate's trust in the leader. Moreover, the mediating effect of the subordinate's trust in the leader on the relationship between perceived leader emotional intelligence and subordinate whistleblowing intentions is stronger when the leader's group prototypicality is high. Academic and practical implications are discussed in the paper.
Data Availability: Data are available upon request.
The Effectiveness of a Proactive, Three-Level Strategy to Identify People With Prediabetes in a Large Workforce With Employer-Sponsored Health Insurance
Authors: Herman William H. , Joiner Kevin , Hurst Thomas , McEwen Laura N. 
Published: May 2021

OBJECTIVE
Rates of diagnosis of prediabetes and uptake of the National Diabetes Prevention Program (NDPP) are low. We evaluated a proactive three-level strategy to identify individuals with prediabetes in a population with employer-sponsored health insurance.

RESEARCH DESIGN AND METHODS
We studied 64,131 insured employees, dependents, and retirees ≥18 years of age without diagnosed diabetes, 19,397 (30%) of whom were estimated to have prediabetes. Individuals with prediabetes were identified by 1) searching claims diagnoses and previously performed HbA1c test results, 2) risk stratifying people 40–64 years of age without diabetes, prediabetes, or documented normal HbA1c to identify individuals at higher risk and encourage them to be tested, and 3) using a media campaign to encourage employees not otherwise targeted to self-screen and, if at higher risk, to be tested.

RESULTS
Using claims and laboratory data, 11% of the population was identified as having prediabetes. Of those 40–64 years of age, 25% were identified as being at higher risk, and 27% of them were tested or diagnosed within 1 year. Of employees exposed to the media campaign, 14% were tested or diagnosed within 1 year. Individuals with prediabetes were older, heavier, and more likely to have hypertension and dyslipidemia. Testing and diagnosis were associated with receiving medical care and provider outreach. A total of 8,129 individuals, or 42% of those with prediabetes, were identified.

CONCLUSIONS
Analysis of existing health insurance data facilitated the identification of individuals with prediabetes. Better identification of people with prediabetes is a first step in increasing uptake of the NDPP.
Application of 2021 American Diabetes Association Glycemic Treatment Clinical Practice Recommendations in Primary Care
Authors: Colling Caitlin , Atlas Steven J. , Wexler Deborah J. 
Published: May 2021

OBJECTIVE
We aimed to identify the proportion of primary care patients meeting criteria for sodium–glucose cotransporter 2 inhibitors (SGLT2is) and glucagon-like peptide 1 receptor agonists (GLP-1 RAs) for cardiorenal comorbidities per 2021 American Diabetes Association (ADA) Standards of Care recommendations using readily available electronic health record (EHR) characteristics.

RESEARCH DESIGN AND METHODS
We applied 2021 ADA recommendations to a primary care cohort of 13,350 adults with type 2 diabetes (T2D).

RESULTS
We found that 33% of patients with diabetes would be eligible for an SGLT2i or GLP-1 RA based on cardiorenal comorbidities, 13% of patients met criteria for an SGLT2i based on heart failure or albuminuric chronic kidney disease (CKD), and 18% of patients met criteria for either agent based on atherosclerotic cardiovascular disease or CKD with an albumin-to-creatinine ratio of ≤300 mg/g.

CONCLUSIONS
This EHR algorithm identified one-third of primary care patients with T2D as meeting criteria for SGLT2i and GLP-1 RA based on strict comorbidity definitions according to 2021 ADA recommendations.
Headache, confusion, and behavioral changes - a HaNDL case report
Authors: Stolz Annaliese , Efendy Rachel , Apte Yogesh 
Published: May 2021

Background:
The clinical syndrome of headache and neurological deficits and cerebrospinal fluid lymphocytosis (HaNDL) is recognized as a self-limiting condition consisting of discrete episodes of neurological deficit associated with moderate to severe headache. The spectrum of neurological features most commonly include aphasia, sensory, and motor disturbances. However, confusion and agitation has also been described.

Case Presentation:
We present an unusual case of a 28-year-old male with recurrent hospital presentations for headache, confusion, and other neurological stigmata over a period of 15 days, culminating in a diagnosis of HaNDL following extensive investigations. He was treated empirically for viral encephalitis initially; however, there were no positive results on virology screening. In addition, autoimmune screens were also negative. He was then managed symptomatically and discharged from hospital with resolution of symptoms thereafter.

Conclusion:
The differential diagnoses for transient acute confusional disorders remain expansive, with HaNDL being one of the many rare causes. Rigorous testing is required to exclude infective, inflammatory, ischemic, structural, or iatrogenic pathology, whil HaNDL primarily remains a diagnosis of exclusion.
ТЕПЛООБМЕН ЭЛЕКТРОПРОВОДНОЙ ЖИДКОСТИ ПРИ БОЛЬШИХ ЗНАЧЕНИЯХ магнитного числа рейнольдса
Authors: Соловьев С.В. , Соловьева Т.С. 
Published: May 2021

Представлены результаты численного моделирования нестационарного конвективного теплообмена и магнитной гидродинамики электропроводной жидкости в сферическом слое при граничных условиях для температуры первого рода. Исследовано влияние величины магнитного числа Рейнольдса на эволюцию структуры течения жидкости, поле температуры, магнитной индукции и распределение чисел Нуссельта.
The results of numerical simulation of unsteady convective heat transfer and magneto hydrodynamics of an electrically conductive fluid in a spherical layer under boundary conditions for a temperature of the first kind are presented. The influence of the value of the magnetic Reynolds number on the evolution of the structure of the fluid flow, the field of temperature, magnetic induction and the distribution of Nusselt numbers is investigated.
The Preservation of English Oak in Marine Environments
Authors: Montgomery Wren , Schofield Eleanor , Sephton Mark A. , Watson Jonathan S. 
Published: May 2021

This study compares the chemical integrity of English Oak (Quercus robur) samples with an age range of four centuries by analysing the lignin degradation. The samples were collected from four historic British vessels and thus represent samples of diverse ages which have nonetheless experienced similar non-arboreal environments. We conclude that the Mary Rose, the oldest vessel studied and the recipient of the most intensive conservation efforts, has been well-preserved through treatment with PEG, and we present a baseline for assessing whether a ship has been biologically degraded.The work combines quantitative analytic chemistry techniques (e.g., THM-GC-MS) with the conservation of large historic artifacts.
La instrucción militar para formar ciudadanos útiles a la nación en la Escuela Industrial Militar de San Luis Potosí durante el porfiriato
Authors: Torres Nava René Alfredo 
Published: May 2021

Durante el porfiriato se establecieron diversas prácticas pedagógicas dentro del proyecto educativo, uno de ellos fue la instrucción militar tema que ha sido poco explorado. El análisis sobre la función la instrucción militar aporta nuevos enfoques a la historiografía de la educación y al estudio sobre el proyecto de Estado encaminados a la formación de ciudadanos, disciplinados y moralizados. En este artículo se analiza la instrucción militar dentro del proyecto educativo porfiriano, puntualizando en los siguientes ejes de análisis: cuál era su función y uso dentro de la educación pública, cómo fue llevada a la práctica la instrucción militar, y cuál era el interés por parte del gobierno de San Luis Potosí, en educar a los niños y jóvenes bajo los dispositivos disciplinarios de esta instrucción.
Семантична репрезентація властивостей їжі у свідомості осіб з орторексією
Authors: Lozova Olga , Fatieieva Maryna 
Published: May 2021

Мета. У статті представлені результати дослідження, метою якого було визначити семантичний простір до поняття «їжа» серед людей з нервовою орторексією. Термін «орторексія» розглядається як нав'язливе прагнення до «здорового й правильного харчування», яке призводить до значних обмежень у виборі їжі, впливає на різні сфери життя, може призвести до соціальної ізоляції.
Методи. У дослідженні використовувались методи вербального семантичного диференціалу та шкали інтуїтивного харчування-2 (Intuitive eating scale-2 в українській адаптації). Основними координатами семантичного простору були статистичні ряди вимірюваних величин, що характеризують взаємодію респондентів з їжею: тактильна привабливість, впорядкованість харчування, оцінка корисності та емоційного змісту їжі. Вибірка охопила 326 випробовуваних у віці від 18 до 68 років (77 чоловіків та 249 жінок). Середній вік становив 30;64 року, стандартне відхилення 11;61.
Результати. Семантичний простір сприйняття їжі респондентами з орторексією охарактеризовано переважанням таких критеріїв: перцептивної привабливості, порядку, корисності, емоційної атрибуції). Найменш важливим для осіб з орторексією виявився критерій перцептивної привабливості. Семантика таких властивостей їжі, як «смачність», «якість», «корисність», «краса», «натуральність» і «жирність» прямо корелює з субшкалами «інтуїтивність харчування», «безумовний дозвіл на приймання їжі», «їжа з огляду на фізичний голод, неемоційний», «покладаюся на сигнали голоду та ситості», «гармонія їжі й тіла».
Висновки. В результаті аналізу окреслено семантичний простір сприйняття їжі респондентами з орторексією. Гіпотезу про зв’язок між семантикою властивостей їжі та рівнями харчової інтуїції суб’єкта верифіковано повністю.