bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accompagnement par les référents professionnels et professionnalisation des stagiaires en formation de moniteur éducateur
Authors: Vidal Nathalie 
Published: September 2021

En quoi la formation en alternance, et plus particulièrement l’accompagnement réalisé en stage par les référents professionnels sont des éléments qualitatifs porteurs dans les processus de professionnalisation des stagiaires moniteurs éducateurs ? Basée sur le concept de représentation en psychologie sociale, l’étude présentée consiste en un croisement des points de vue des stagiaires et des référents professionnels. Les quatre entretiens menés auprès des référents ainsi que les quarante-deux questionnaires de stagiaires première année et les trante-sept questionnaires des stagiaires deuxième année sont analysés au moyen de deux logiciels de lexicométrie, ALCESTE et LEXICO. Les résultats mettent en avant la notion de « solidarité professionnalisée » et la nature d’« accompagnement au quotidien par une équipe pluridisciplinaire » de l’activité comme éléments saillants de ce qui se transmet de génération professionnelle en génération professionnelle.
Comparative Analysis of Alternative Splicing Profiles in Th Cell Subsets Reveals Extensive Cell Type–Specific Effects Modulated by a Network of Transcription Factors and RNA-Binding Proteins
Authors: Mir Quoseena , Lakshmipati Deepak K , Ulrich Benjamin J , Kaplan Mark H , Janga Sarath Chandra 
Published: September 2021

Abstract
Alternative splicing (AS) plays an important role in the development of many cell types; however, its contribution to Th subsets has been clearly defined. In this study, we compare mice naive CD4+ Th cells with Th1, Th2, Th17, and T regulatory cells and observed that the majority of AS events were retained intron, followed by skipped-exon events, with at least 1200 genes across cell types affected by AS events. A significant fraction of the AS events, especially retained intron events from the 72-h time point, were no longer observed 2 wk postdifferentiation, suggesting a role for AS in early activation and differentiation via preferential expression of specific isoforms required during T cell activation, but not for differentiation or effector function. Examining the protein consequence of the exon-skipping events revealed an abundance of structural proteins encoding for intrinsically unstructured peptide regions, followed by transmembrane helices, β strands, and polypeptide turn motifs. Analyses of expression profiles of RNA-binding proteins (RBPs) and their cognate binding sites flanking the discovered AS events revealed an enrichment for specific RBP recognition sites in each of the Th subsets. Integration with publicly available chromatin immunoprecipitation sequencing datasets for transcription factors support a model wherein lineage-determining transcription factors impact the RBP profile within the differentiating cells, and this differential expression contributes to AS of the transcriptome via a cascade of cell type–specific posttranscriptional rewiring events.
TEG Parameters Maximum Amplitude, Reaction Time Predicts Sepsis-Induced Coagulopathy and Mortality: A Prospective, Observational Study
Authors: Li Xin , Wang Liang , Liang Yingjian , Li Lu , Li Xiaotong , Zhang Zhidan , Zhang Xiaojuan 
Published: September 2021

Abstract

Introduction:
The diagnostic and prognostic value of thromboelastogram (TEG) in sepsis has not been determined. This study aimed to assess whether TEG is an early predictor of coagulopathy and is associated with mortality in patients with sepsis.

Methods:
In total, 518 patients with sepsis on the intensive care unit (ICU) admission were prospectively evaluated. We measured TEG and conventional coagulation tests on preadmission to ICU and observed for the development of 1 and 3 days and 1, 3, and 7 days, respectively. Multivariable logistic regression was utilized to determine the odds of ICU/hospital mortality. The parameter of TEG (maximum amplitude, reaction time; MA/R ratio) was calculated to evaluate sepsis-induced coagulopathy. The patients were divided into three groups: MA/R0 group (MA/R = 5-14 mm/min); MA/R1 group (MA/R <5 mm/min); and MA/R2 group (MA/R >14 mm/min).

Results:
Four hundred and ten patients were included. At enrolment, 10.73%, 65.85%, and 23.41% of the patients had lower, normal, and higher MA/R state, respectively. Compared to MA/R0 group, patients with lower and higher MA/R both had significantly increase risk of hospital mortality (hazards ratio [HR] 2.83 [95% confidence interval [CI] 1.577-5.079], P < 0.01); (HR 1.982 [95% CI 1.073-3.66], P = 0.029), respectively (adjusted with Acute Physiology and Chronic Health Evaluation [APACHEII] score) and ICU mortality (HR 2.512 [95% CI 1.301-4.852], P = 0.006); (HR1.644 [95% CI 1.024-2.639], P = 0.002) (adjusted with APACHEII score). Patients with higher MA/R had significantly increase risk of hospital mortality APACHE II score (HR 1.635 [95% CI 1.016-2.632], P = 0.043).

Conclusions:
In our cohort of patients with severe sepsis, coagulopathy defined by MA/R ratio was associated with increased risk of ICU/hospital mortality.
Evolving trends of distance learning for basic education in Namibia: A parental perspective during Covid-19 lockdown
Authors: Strauss Annaly M. , Bipath Keshni 
Published: September 2021

Ingenious technology-driven education has become prevalent during the COVID-19 pandemic in schools. This article solicits pre-primary to Grade 12 learners' parents’/ guardians’ views and experiences of distance learning in Namibia during the COVID-19 lockdown. The study employs a mixed-methods research design to gather and analyse data. The analysis of the qualitative data revealed the following main themes: 1) Barriers to distance learning, and 2) Suggestions to overcome these challenges. The sub-themes were: 1) Communication, 2) Teaching and learning 3) Economic challenges, and 4) Materials and equipment. The results of a quantitative analysis revealed that 73,7% of the participating parents’ children had not received any form of education, and 23,7% affirmed that their children had received some education. 53% of the parents whose children had received an education were very dissatisfied. Therefore, the participating parents’ expectations of e-learning were not positively associated with the provision thereof. Lack of digital literacy prevented teachers from actively engaging with learners in digital communities.
Addressing the challenge of over-crowdedness in English First Additional Language (EFAL) classrooms
Authors: Ntsala Sekanse Abiner , Ramabenyane Mamosebatho Julia , Koen Mariette , Loock Irma 
Published: September 2021

This paper lends itself to extenuating the impact of over-crowdedness in the intermediate phase EFAL classrooms. An in-depth investigation into the causes of poor performance in the intermediate phase EFAL classrooms revealed over-crowdedness as one of the main possible causes. The pedagogical impediments that result from this phenomenon affect the intermediate phase EFL teachers more due to the curriculum requirements of this subject. The study was conducted in the Motheo Education District, in the Free State Province. The data was collected qualitatively, through the use of a group interview, semi-structured interviews and observations. The interviews focused on both well-performing and poor performing schools, while the observations focused on the well-performing schools. The data, which was analysed thematically, revealed the following practices that can benefit EFAL teachers working in overcrowded intermediate phase classrooms: effective planning and preparation, the integration of skills, constructive teaching, explicit instruction, a selective approach, notetaking and the process approach. The study was premised on the theory of hope, as the insights from well-performing schools expound the importance of not losing hope and remaining motivated to mitigate contextual factors.
Profesor Tadeusz Estreicher (1871–1952) – chemik, kriogenik, historyk nauki, miłośnik sztuki, humanista, tłumacz i patriota
Authors: Rafalska-Łasocha Alicja 
Published: September 2021

Chemik Tadeusz Estreicher, uczeń prof. Karola Olszewskiego, zajmował się głównie kriogeniką, jego działalność obejmowała również wiele innych dziedzin nauki, kultury i sztuki. Swój czas poświęcał on też na działalność społeczną, szczególnie w czasie pobytu i pracy na uniwersytecie w szwajcarskim Fryburgu.
Po odzyskaniu niepodległości prof. Tadeusz Estreicher wrócił do kraju i rozpoczął pracę organizacyjną i naukową. Związany był z Wydziałem Filozoficznym (Katedra Chemii), Oddziałem Farmaceutycznym UJ i krakowską Akademią Sztuk Pięknych.
W 1939 r. został aresztowany w trakcie Sonderaktion Krakau i przebywał w obozie w Sachsenhausen. Po powrocie do Krakowa brał udział w tajnym nauczaniu, a po zakończeniu wojny powrócił do pracy w I Zakładzie Chemicznym Collegium Chemicum przy ul. Olszewskiego 2.
Po jego śmierci, w nekrologu, jaki ukazał się w czasopiśmie Nature, John Read napisał: „Będąc przede wszystkim chemikiem, Estreicher był wielkim erudytą i miał wiele różnorodnych zainteresowań. Ten wybitny uczony mógłby przyjąć za swoje motto: Homo sum humani: nihil a me alienum puto.”
Celem artykułu jest przypomnienie postaci Tadeusza Estreichera i uzupełnienie jego biografii o nowe wątki dotyczące jego zainteresowań sztuką i kontaktów ze środowiskiem artystycznym Krakowa.
Probabilidade: as relações entre conceitos e contextos a partir de um recurso didático
Authors: Barbosa Kátia Xavier Rodrigues , De Melo Diógenes Maclyne Bezerra 
Published: September 2021

Esse artigo tem como objetivo analisar se o jogo da memória “será que vai acontecer?”, enquanto recurso didático, permite que os estudantes consigam transferir a aprendizagem de um determinado contexto para outro contexto. Tomamos como fundamentação teórica para análise, os tipos de contextos proposto por Ole Skovsmose (2000). No procedimento metodológico realizamos uma pesquisa de campo e organizamos em três momentos. O primeiro, consistiu na aplicação de uma atividade diagnóstica pré-jogo, no contexto da semi-realidade, para identificar que compreensão os alunos tinham sobre os conceitos de probabilidade. No segundo momento, foi aplicado o jogo Será que vai acontecer? no contexto da matemática pura para que os alunos fossem se apropriando dos conceitos e se familiarizando com os termos que representam os respectivos conceitos. Por fim, foi aplicada uma nova atividade diagnóstica no contexto da semi- realidade para verifica verificar se os alunos conseguiram transferir a aprendizagem de um determinado contexto para o outro. Os resultados dessa análise permitiram perceber que os estudantes tiveram 100% de aproveitamento no conceito certo, fazendo associação de um contexto da matemática pura para o contexto da semi-realidade. No entanto, não teve muita influência no conceito de talvez aconteça e impossível pela natureza particular das situações e distintas em cada um dos contextos.

This article aims to analyze whether the memory game “will it happen?”, as a didactic resource, allows students to transfer learning from a given context to another context. We take as theoretical foundation for analysis, the types of contexts proposed by Ole Skovsmose (2000). In the methodological procedure, we carried out a field research and organized it into three stages. The first consisted in the application of a pre-game diagnostic activity, in the context of semi-reality, to identify what understanding the students had about the concepts of probability. In the second moment, the game Will it happen? in the context of pure mathematics, so that students could take ownership of the concepts and become familiar with the terms that represent the respective concepts. Finally, a new diagnostic activity was applied in the semi-reality context to verify if students were able to transfer learning from one context to another. The results of this analysis allowed us to realize that the students had 100% success in the right concept, associating a context of pure mathematics to the context of semi-reality. However, it did not have much influence on the concept of maybe happening and impossible due to the particular nature of the situations and distinct in each context.
EVALUATION OF THE ENGLISH LANGUAGE TEACHING PROGRAM OF THE FACULTY OF EDUCATION, UNIVERSITY OF BENGHAZI USING THE PEACOCK MODEL: TOWARDS QUALITY EDUCATION
Authors: Laurel Regilito D. , Belting Annabelle C. , Almansouri Ennaji Omran 
Published: September 2021

<p>The English Language Teaching (ELT) is a theory and practice of English teaching and learning for the welfare of the non-native students whose language is not English. It is an English language degree in exploring the application of the language development and current practice in teaching and testing. The study aims to identify the aspects of the English Language Teaching (ELT) and how do the aspects of the English Language Teaching (ELT) program should be maintained and improved based on the Peacock’s Model and Evaluation. The study employs the quantitative and qualitative descriptive research design and method. The study comprised seventeen (17) alumni of the Faculty of Education, English Department, University of Benghazi, Libya as these participants had experienced the evaluation of the English Language Teaching program to be maintained and to be improved in the Faculty of Education. Purposive sampling is utilized in the study because it is non-probability which is known as judgmental, subjective, and selective sampling. Results show that participants are encouraged to be a reflective teacher when they start teaching and taught to evaluate themselves as a teacher which is vital and important in ELT profession in the Faculty of Education and in English as a Foreign Language, show to promote flexibility in using different teaching practices in different situation and classroom management skills in terms of participation, show that there is adequate training and teaching skills and balances of teacher-centered and student-centered learning on its courses in ELT in terms of experimentation, show to avoid overlapping information between different courses and are ready to teach ELT of the program in the university in terms of application, and show that participants are encouraged to reflect on their past experiences as a language learners and are encouraged to be a reflective teacher in their teaching process in terms of cooperation.</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0863/a.php" alt="Hit counter" /></p>
Prof. Dr. Michel Zerah
Authors: De Oliveira Ricardo Santos , Ballestero Matheus Fernando Manzolli 
Published: September 2021

Michel Zerah was born on May 22, 1956 in Paris, France. He finished his medical study in 1985 at Faculté de médecine de CRETEIL (Paris, France) and graduated in Neurosurgery in April, 1988.
Quickly took over as head of Clinic-Assistant of Paris Hospitals, “Service de Neurochirurgie de l’hôpital de Bicêtre” (1989) and as university professor (1998) at “Service de Neurochirurgie pédiatrique” of hospital group “Necker-Enfants Malades”.
Prof. Zerah was a great teacher and mentor to countless neurosurgeons, around the world and here in Brazil.
He participated in several courses and congresses, highlighting his unconditional dedication to teaching. With his knowledge, his humility and incredible charisma he made countless friends and students wherever he went. His lectures have always been unique experiences, approaching each subject in a masterly way, with emphasis on craniocervical transition diseases and spinal dysraphimos.
He has authored more than 261 scientific articles and several books and book chapters, with emphasis on lumbar lipomas surgery, Chiari, deposit diseases, among others. His last project was the development of fetal surgery at Necker Hospital.
Michel Zerah had an incredible ability to bring people together and, thus, he walked a path of respect, affection and friendship wherever he went.
He was head of the Pediatric Neurosurgery Service at Hospital Necker, Paris, France where he devoted a large part of his life, teaching and operating numerous children.
An immense and irreparable loss for everyone who knew him and who had the privilege of working and living with him.
Short Biography:

Head of the Pediatric Neurosurgery Service – Hospital Necker, Paris, France
President of the European Society for Pediatric Neurosurgery (ESPN)
President of the French Society of Pediatric Neurosurgery
Member of the French National Academy of Surgery
PhD in Mathematics, Statistics and Computer Science
Coordinator of the European Course on Pediatric Neurosurgery between 2002 and 2014.
Collaboration with the Society of Neurosurgery of Vietnam where he practiced solidarity work and trained numerous professionals.
324 communications or conferences in National or International Meetings
32 Chapters in Books
123 articles in Scientific Journal
Management of Pseudotumor Cerebri Secondary to Dural Venous Sinus Thrombosis in Children
Authors: Elsherbini Mohamed M , Badr Hatem , Kassem Mohamed , Khalil Amr Farid 
Published: September 2021

Background: The purpose of this study is to follow the clinical course and required management of children suffering from Pseudotumor cerebri (PTC) secondary to Dural Sinus Thrombosis (DST) to understand the natural history of a rare condition and its need for surgery as well as outcome after Cerebro-Spinal Fluid (CSF) diversion surgeries.
Methods: A retrospective consecutive case series study based on examining medical records of patients who were referred to neurosurgical pediatric clinic suffering from PTC secondary to DTS. Data review included patients’ archives for clinical, radiological, surgical records and follow up visits. Only patients below 18 years old were included.
Results: Fourteen patients met inclusion criteria, 7 of them required CSF diversion procedure, while the other 50% responded to medical conservative therapy. Headache improved immediately for most of the surgical group, while took 7 weeks to reach satisfactory results for medical group. Visual improvement took place for both groups approximately at the same time interval with average 5 weeks.
Conclusion: Surgical intervention in the form of CSF diversion procedure was required for 50 % of the patients, which is safe and effective line of treatment to prevent further deterioration of vision for case who were not responsive to medical therapy.
Imaging differentiation on extra-axial fluid collections: a clinical Image.
Authors: Gutierrez Pineda Felipe 
Published: September 2021

A 3 month – old male patient with a history of seizures presents to the Pediatric neurosurgery department with his parents, on initial evaluation a head circumference of 47.5 cm (> percentile 99 on the WHO chart) was seen. A brain MRI was performed and an extra axial fluid collections (Chronic subdural hematoma and benign external hydrocephalus) was diagnosed. His parents refer a normal delivery without any complication and the medical history and records denied any previous trauma.
A neurosurgical evacuation of the subdural hematoma was performed, and a complete improvement of his seizure was seen on 3 months follow up.
Benign external hydrocephalus (BEH) has been proposed as a risk factor for the presence of chronic subdural hematoma (SDH) in infants (1). The SDH formation in the presence of BEH has been reported to be a venous rupture either spontaneously or following minor trauma from the bridging veins traversing the subdural/subarachnoid space (Red arrow , image D ) that are stretched with enlarged extra?axial collections (2).
Epidemiologically there are striking similarities between these entities (3) that can be differentiated by some MRI findings.The signs that help us in the differentiation are: the subarachnoid layer visible (yellow arrow image B, showing a displaced subarachnoid layer downward by a fluid between it and the dura) the absence of the cortical vein sign and the differential on fluid intensity on T1-T2 weighted images (Images A,B,C,D) (4). Surgery evacuation is necessary for the patients with chronic subdural hematoma associated with BEH and neurological signs of increased intracranial pressure like macrocrania, seizures and altered level of consciousness (Image F , showing the subdural space without hematoma and the subarachnoid layer downward it ) (5).
La ciudad contemporánea: Identidad y patrimonio
Authors: Rocha Irving Samadhi Aguilar 
Published: September 2021

Esta reflexión crítica de corte teórico-filosófica toma como objeto de estudio la ciudad y, más específicamente, la transformación que ha sufrido esta idea o conceptualización frente a las nuevas formas de vida, de organización y de control, potencializadas por el desarrollo de la tecnología y la colonización del pensamiento y la vida.
Los habitantes de los pueblos o espacios rurales sufren transformaciones en su estilo de vida con la expansión de la ciudad o mancha urbana, generando la aparición de las formas de vida modernas y tecnológicas que se desarrollan en estas y a las cuales se adaptan. Las prácticas de agricultura poco a poco son desplazadas por las nuevas tecnologías de la urbanización; junto con ello las costumbres y tradiciones se modificarán creando una combinación entre lo urbano y lo rural, poniendo sobre la mesa la discusión en torno a la identidad de los habitantes. Un ejemplo de esto es el poblado de Ocotepec, en el estado de Morelos, cuyo proceso de urbanización resulta más que evidente. Lo interesante de Ocotepec consiste en el hecho de que en el 2014 la UNESCO le otorgó al pueblo el reconocimiento como patrimonio inmaterial cultural por sus costumbres del Día de Muertos, y además de que es considerado pueblo indígena. Esto fue posible porque frente a la expansión de la ciudad y su urbanización se contempló dentro del discurso político de la UNESCO el proteger este patrimonio. De aquí que se vuelva fundamental abordar los temas de la identidad, el patrimonio y las ciudades contemporáneas, caracterizadas como “machas urbanas”, lo que abre la reflexión en torno a las dos categorías que nos permitirán aquí analizar éstas: se trata del lugar y del no lugar, de la mano de Marc Augé.

This philosophical reflection takes the city as the object of study and specifically the transformation of this idea or this concept before the new forms of life, of organization and control, increased by the technological development and the colonization of thought and life.
The inhabitants of a town suffer transformations in their lifestyle with the expansion of a city or an urban spraw, generating new modern and technological ways of life. The agriculture becomes replaced by new technological urbanization and also the ways and traditions change, creating a combination between the country and the urban that questions the identity of their population. As an example of this there is a country called Ocotepec in the state of Morelos, Mexico. The most interesting part of this town is that in 2014 the UNESCO granted Ocotepec the cultural heritage recognition because of the day of the dead, and that it is considered a native country. From this point on becomes fundamental the approach to the subjects of identity, heritage and contemporary cities, also named urban spraws, that open a new reflection in two categories: one being space and the other not space, following Marc Augé proposal.