bluuebunny/crossref_metadata_2025_split huggingface dataset:
Smart Dustbin Using IOT Notification
Authors: Singh Anuradha , Tiwari Prabhakar 
Published: July 2021

Abstract
In today's world, we frequently witness rubbish bins or dust bins are located in cities and in public places due to overflowing the daily growth in the garbage. This generates an unsanitary environment for humans and a foul odor in the surrounding area, which contributes to the spread of lethal illness and human diseases. Avoid to this, our purpose is constructing for a "Smart Dustbin Using IOT Notifications." Several rubbish bins may be found all through the cities or even on campuses in this proposed system; those kind of waste can is equipped such as a embedding gadget at a cheap price that supports track the height of the waste cans, as well as this is unique identification for everyone rubbish bin in the city, making it is easy to classify which rubbish bins has been fully mode. That gadget will broadcast is level together with unique ID specified when it hits the threshold limit. These facts can be viewed by concerned authorities over the internet from their location, allowing them to take rapid action to clean the trash cans. The government began a number of projects to improve the country's cleanliness. This paper is beneficial to the government's "SWACHH BHARAT ABHIYAN" project. Waste management is currently one of the world's most pressing issues, regardless of whether a country is developed or developing. The main problem with trash management is that garbage in public locations overflows well before the next cleaning operation begins. It therefore leads to different hazards, such as a faulty door and ugliness in the area, which may be the source of disease transmission. This effort is based on a smart waste system to avoid any potentially dangerous scenarios and to ensure public cleanliness and health. The primary goal for this paper aims to develop an intelligent waste alert system collection by the sending a notification to a municipality web application immediate dust bin clean and a notification to a Municipality web application waste fill levels. These procedures are facilitated with a sensors built of ultrasonic waves these are connected to an UNO (Arduino Uno) and checks the levels of the waste inside the dust bin, sending and a notification to the municipality web application if the bin has been fully mode. The entire procedure is supported by an embedded module that utilities IOT facilitation. With the help of this system, the Municipality authorities can monitor and follow up on the in near real - time, the condition of waste collection. In addition, to the appropriate corrective actions might perhaps be adjusted. To accomplish this, an Android application has been created and connects to the web application. Sends an alarm and from micro - controller to the city workplace and to keep an eye on the removal process from afar performed through the employees, eliminating manual inspection and confirmation procedure to transfer the data, the Wi-Fi chip is required and notifications is to the Android app.
Women’s decision in family planning use and its determinants in Ethiopia. A systematic review and meta-analysis protocol
Authors: Anbesu Etsay Woldu , Aychiluhm Setognal Birara , Alemayehu Mussie 
Published: July 2021

Abstract
Background: Low uptake of contraceptive use have much consequence. Despite this effect, less emphasis was given to women’s decision-making on family planning use in Ethiopia. Though there are studies conducted in different parts of the country on women’s decision-making in family planning use, there are inconsistent findings. Thus, this systematic review and meta-analysis aimed to determine the pooled prevalence of women’s decision-making in family planning use and its determinants in Ethiopia.Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline will be followed to develop the review protocol. All observational studies will be retrieved using Medical Subject Heading (Mesh) terms or keywords from online databases PubMed, CINAHL, Google Scholar, and grey literature. The quality of the studies will be critically assessed using Joanna Briggs Institute checklist. Heterogeneity among studies will be examined using I-squared statistics. Funnel plots and Egger’s test will be used to examine Publication bias. The Meta-analysis will be performed using STATA version 14 software. Statistical significance will be determined at 95% CI.Discussion: Improving women’s autonomy on decision-making on reproductive health services including contraceptive use has a substantial advantage. There are studies on women's decision-making in family planning use, however, there are inconsistent findings. Therefore, this review aims to determine the pooled prevalence of women’s decision-making in family planning use and its determinants in Ethiopia. The finding from this systematic review and meta-analysis will help to inform policymakers to develop appropriate interventions to improve women's decision-making in family planning use.
Development and validation of a prognostic model to predict clinical deterioration in hospitalized patients with COVID-19
Authors: Azadbakht Javid , Kooraki Soheil , Rashedi Sina , Kowsari Hamed , Tabibian Elnaz 
Published: July 2021

Abstract
Objectives

We aimed to develop and validate a prognostic model to predict clinical deterioration defined as either death or intensive care unit admission of hospitalized COVID-19 patients.
Methods

This prospective, multicenter study investigated 172 consecutive hospitalized COVID-19 patients who underwent a chest computed tomography (CT) scan between March 20 and April 30, 2020 (development cohort), as well as an independent sample of 40 consecutive patients for external validation (validation cohort). The clinical, laboratory, and radiologic data were gathered, and logistic regression along with receiver operating characteristic (ROC) curve analysis was performed.
Results

The overall clinical deterioration rates of the development and validation cohorts were 28.4% (49 of 172) and 30% (12 of 40), respectively. Seven predictors were included in the scoring system with a total score of 15: CT severity score\(\ge\)15 (Odds Ratio (OR)=6.34, 4 points), pleural effusion (OR = 6.80, 2 points), symptom onset to admission ≤ 6 days (OR = 2.44, 2 points), age\(\ge\)70 years (OR = 2.44, 2 points), diabetes mellitus (OR = 2.24, 2 points), dyspnea (OR = 2.17, 1.5 points), and abnormal leukocyte count (OR = 1.89, 1.5 points). The area under the ROC curve for the scoring system in the development and validation cohorts was 0.823 (CI [0.751–0.895]) and 0.558 (CI [0.340–0.775]), respectively.
Conclusion

This study provided a new easy-to-calculate scoring system with external validation for hospitalized COVID-19 patients to predict clinical deterioration based on a combination of seven clinical, laboratory, and radiologic parameters.
Aflatoxin Exposure among Children of age 12-59 Months in Butajira District, South-Central Ethiopia: a community based cross-sectional study
Authors: Ayele Mary , Haile Demewoz , Alonso Silvia , Sime Heven , Abera Adugna , Balcha Kifle Habte , Roba Kedir Tej , Guma Geremew Tasew , Endris Bilal Shikur 
Published: July 2021

Abstract
Background

The continued provision of safe food, free of aflatoxin remains a huge challenge in developing countries. Despite several favourable climatic conditions that facilitate aflatoxin contamination in Ethiopia, there is little information showing aflatoxin exposure in children. Therefore, this study assessed aflatoxin exposure among young children in Butajira district, South-Central Ethiopia.
Methods

Community based cross-sectional study stratified by agro-ecology was employed in Health and Demographic Surveillance Site (HDSS) of Butajira. The study included 332 children aged 12–59 months and were selected by simple random sampling technique using the HDSS registration number as a sampling frame. We collected data on dietary practice and aflatoxin exposure. Aflatoxin M1 concentration in urine was measured by Enzyme-Linked Immunosorbent assay (ELISA).
Results

Detectable urinary Aflatoxin M1 was found in 62.4% (95% CI: 56.9–67.5%) of the children at a level ranging from 0.15 to 0.4ng/ml. Children living in lowland agro-ecological zone had [AOR = 2.11 (95% CI; 1.15, 3.88] about 2 folds higher odds of being exposed to aflatoxin as compared to children living in highland agro-ecological zone. Children at lower socio-economic status [AOR = 0.27 (95% CI; 0.14, 0.50] and medium socio-economic status [AOR = 0.47 (95% CI; 0.25, 0.87] had 73% and 53% lower odds of being exposed to aflatoxin as compared to children in the higher socio-economic status, respectively.
Conclusions

Aflatoxin exposure among young children was very high in South-Central Ethiopia. This high aflatoxin exposure might emphasize the need for aflatoxin exposure mitigation strategies in Ethiopia. Further research is required to assess long-term aflatoxin exposure and its association with child growth and development.
PENGARUH PROMOSI MEDIA SOSIAL, CELEBRITY ENDORSER, DAN PERCEIVED QUALITY TERHADAP KEPUTUSAN PEMBELIAN
Authors: Sisnuhadi Sisnuhadi , Sirait Stefanus Kevin 
Published: July 2021

ABSTRAK Penelitian ini dilakukan untuk mengeksplorasi dampak promosi media sosial, celebrity endorser, dan perceived quality terhadap keputusan pembelian pada produk SuperTrack Clothing di Daerah Istimewa Yogyakarta. Regresi linier berganda diterapkan untuk signifikansi antar variabel, dan uji koefisien determinasi. Variabel independen dalam penelitian ini yaitu promosi media sosial, celebrity endorser, dan perceived quality sedangkan variabel dependen dalam penelitian ini adalah keputusan pembelian. Penelitian ini menemukan bahwa bahwa semakin gencar promosi media sosial akan meningkatkan keputusan pembelian, semakin terkenal celebrity endorser akan meningkatkan keputusan pembelian, semakin kuat perceived quality yang dimilliki konsumen, akan mendorong peningkatan keputusan pembelian. Kata Kunci: promosi media sosial, celebrity endorser, perceived quality, dan keputusan pembelian ABSTRACT This research was conducted to explore the impact of social media promotion, celebrity endorsers, and perceived quality on purchasing decisions on SuperTrack Clothing products in the Special Region of Yogyakarta. Multiple linear regression was applied for significance between variables, and the coefficient of determination test. The independent variables in this study are social media promotion, celebrity endorser, and perceived quality, while the dependent variable in this study is the purchase decision. This study found that the more intense social media promotion will increase purchasing decisions, the more well-known celebrity endorsers will improve purchasing decisions, the stronger the perceived quality that consumers have, will encourage an enhance in purchasing decisions.Keywords: social media promotion, celebrity endorser, perceived quality, and purchasing decisions
Efektifitas Penggunaan Kembang Sepatu sebagai Indikator Alam untuk Identifikasi Senyawa Asam Basa
Authors: T Nur Elisa Hawa , Mulyanti Sri 
Published: July 2021

Asam dan basa merupakan suatu zat yang dapat mengionisasi ion H+ dan ion OH- dalam larutan. Untuk mengidentifikasi suatu zat yang bersifat asam dan basa bisa menggunakan indikator bahan alam. Penelitian ini bertujuan untuk mengetahui komposisi jumlah kembang sepatu dan air yang digunakan sebagai pelarut, dengan bahan, alat dan metode sederhana. Metode penelitian ini menggunakan uji optimalisasi. Hasil dari penelitian ini memiliki perbedaan respon bahan yang bersifat asam maupun basa saat diidentifikasi menggunakan kembang sepatu yang sudah digiling dengan pelarut air menggunakan jumlah Kembang Sepatu (KS) yang berbeda yaitu A terdiri dari 5 buah KS, B 10 buah KS, dan C 15 buah KS. Perubahan warna tersebut seiring dengan perubahan struktur dari senyawa metabolit sekunder yang terkandung pada kembang sepatu yakni antosianin pada setiap kondisi pH. Percobaan dengan jumlah kembang sepatu yang sedikit dan air yang lebih sedikit menunjukkan degredasi warna di setiap percobaan. Percobaan yang menggunakan kembang sepatu dan air yang lebih banyak terlihat bahwa warna yang dihasilkan semakin pekat akan tetapi degredasi warnanya tidak berubah secara signifikan jika dibandingkan dengan pengujian pada kode A1 (kembang sepatu dengan jeruk manis), A2 (kembang sepatu dengan jeruk nipis), A3 (kembang sepatu dengan cuka), A4 (kembang sepatu dengan soda kue), dan A5 (kembang sepatu dengan sabun cair). Kembang sepatu dapat dijadikan sebagai indikator alam karena pada kembang sepatu terdapat struktur senyawa antosianin pada setiap pH.
Silica-Rice Husk as Adsorbent of Cr (VI) Ions Prepared through Sol-Gel Method
Authors: Rodiah Siti , Huljana Mifta , Al Jabbar Jauharuddin Luthfi , Ichsan Chairul , Marzuki Hasan 
Published: July 2021

One of the heavy metals contained in the textile industry wastewater is chromium (Cr). Chromium hexavalent ions (Cr6+) are highly toxic and its accumulation in the human body will cause various negative impacts. This study aimed to determine the characteristics of silica synthesized by the sol-gel method to gain homogeneity and high purity. Synthesized silica was calcined at 700°C for 4 hours and its performance to adsorb Cr(VI) ions in textile wastewater was investigated. The presence of -OH group from silanol (–Si-OH) was appeared at wavenumber 3367.70 cm-1, meanwhile siloxane functional groups were recorded at 1056.99 cm-1 and 784.38 cm-1 due to the O-Si-O asymmetric stretching and Si-O bending vibration. Optimum conditions of silica to adsorb Cr(VI) ions took place at pH 2 and contact time of 90 minutes by adsorption efficiency of 75,65% and followed the Freundlich isotherm.
Embolismo pulmonar masivo y trombo en ventrículo derecho post-infarto agudo de miocardio
Authors: Mera-Martínez Paulo Francisco , Guerrero-Montero Aida Gabriela , Araujo Prado Laura María , Portillo Miño José Darío 
Published: July 2021

Introducción: un trombo en ventrículo derecho y embolismo pulmonar post infarto agudo de miocardio sin elevación del ST es muy inusual. Es considerado una emergencia médica y es imperativo instaurar una opción terapéutica inmediata. Presentación del caso: paciente femenina de 80 años consulta a la sala de emergencias por síncope, dolor torácico y disnea persistente. Se confirmó síndrome coronario agudo por electrocardiograma y troponina I elevada. En estudios complementarios se encontró hallazgo incidental de trombo en el ventrículo derecho y un angio-TAC confirmó embolismo pulmonar masivo. Discusión: el trombo en ventrículo derecho y embolismo pulmonar masivo post infarto es un fenómeno muy raro en el escenario clínico debido a la instauración temprana de la terapia anti-isquémica. Es necesario mayor investigación para aclarar este fenómeno.
Palabras clave: Infarto agudo de miocardio; Trombo; Ventrículo derecho; Embolismo pulmonar masivo.
The Cardiovascular Benefits of Caffeinated Beverages: Real or Surreal? “Metron Ariston - All in Moderation”
Authors: Manolis Antonis A. , Manolis Theodora A. , Apostolopoulos Evdoxia J. , Melita Helen , Manolis Antonis S. 
Published: July 2021

:Caffeinated beverages are the most widely consumed beverages globally with coffee and tea as the two most prominent sources of caffeine. Caffeine content varies across different types of beverages. In addition to caffeine, coffee and tea have other biologically active compounds, and all may affect general and cardiovascular (CV) health. Moderate caffeine consumption (<300-400 mg/day), regardless of the source, is considered safe by both European and US Health Authorities, as it is not associated with adverse health and CV effects, while it may confer certain health benefits. There is a nonlinear association between coffee ingestion and CV risk; moderate coffee drinking is inversely significantly associated with CV risk, with the highest benefit at 2-4 cups per day, while heavy coffee drinking might confer increased risk. With regards to tea, due to a lower caffeine content per serving, its consumption is only limited by the total caffeine daily intake. Both these caffeinated beverages, coffee and tea, have additional phenolic compounds, with anti-oxidant and anti-inflammatory activities, which confer cardioprotective benefits. Of the several coffee compounds, chloroacetic acids and melanoidins offer such beneficial effects, while diterpenes may have unfavorable effects on lipids. Most of the tea ingredients (polyphenols) are cardioprotective. A major concern relates to energy drinks with their much higher caffeine content which puts individuals, especially adolescents and young adults, at high health and CV risk. All these issues are herein discussed, including pertinent studies and meta-analyses, pathogenetic mechanisms involved and relevant recommendations from health authorities.
The Regulatory Role of Pivotal MicroRNAs in the AKT Signaling Pathway in Breast Cancer
Authors: Taefehshokr Sina , Taefehshokr Nima , Derakhshani Afshin , Baghbanzadeh Amir , Astamal Reza Vaezi , Safaei Sahar , Abbasi Samane , Hajazimian Saba , Maroufi Nazila Fathi , Isazadeh Alireza , Hajiasgharzadeh Khalil , Baradaran Behzad 
Published: July 2021

:Breast cancer is the most prevalent type of cancer among women, and it remains the main challenge despite improved treatments. MicroRNAs (miRNAs) are a small non-coding family of RNAs that play an indispensable role in regulating major physiological processes, including differentiation, proliferation, invasion, migration, cell cycle regulation, stem cell maintenance apoptosis, and organ development. The dysregulation of these tiny molecules is associated with various human malignancies. More than 50% of these non-coding RNA sequences estimated have been placed on genomic regions or fragile sites linked to cancer. Following the discovery of the first signatures of specific miRNA in breast cancer, numerous researches focused on involving these tiny RNAs in breast cancer physiopathology as a new therapeutic approach or as reliable prognostic biomarkers. In the current review, we focus on recent findings related to the involvement of miRNAs in breast cancer via the AKT signaling pathway related to their clinical implications.
QbD-Enabled Systematic Development of Ileo-Colonic Targeted Novel Mucoadhesive Microspheres of Flurbiprofen
Authors: Pande Saikat , Vashi Janu , Solanki Ajay 
Published: July 2021

Background:
Flurbiprofen (FLBP), used in the treatment of ulcerative colitis, has a
short biological half-life. Frequent intake of FLBP may lead to some serious gastric complications,
which makes FLBP an ideal candidate for sustained release preparation to the Ileo-colonic region
of the gastrointestinal tract (GIT).

Objective:
The objective of this study was to investigate the potential of Eudragit coated chitosan
microspheres in delivering Flurbiprofen in a sustained manner to the Ileo-colonic region of the GIT
for treatment of ulcerative colitis.

Methods:
In the present study, mucoadhesive chitosan microspheres were prepared using the emulsion
solvent evaporation method by varying different process parameters. Optimized chitosan microspheres
were coated with Eudragit L-100 and Eudragit S-100. A 32 full factorial design was applied
for optimization. The effect of independent variables (Eudragit L-100 to Eudragit S-100 ratio
and stirring speed) on dependent variable i.e. percentage cumulative drug release (%CDR) at 3 h
and 24 h was evaluated. The optimized batch was evaluated by FT-IR, DSC study, XRD study and
SEM analysis.

Results:
Discrete spherical shape chitosan microspheres with entrapment efficiency of up to 95.4%
were obtained and selected for coating. Chitosan microspheres were coated successfully with different
ratios of Eudragit L-100 to Eudragit S-100. The release profile of the optimized batch matches
with the desired release profile. FLBP was found to be stable and molecularly dispersed in the polymer
matrix.

Conclusion:
Taken together it can be concluded that prepared microspheres may be considered as
a suitable for delivering FLBP to the Ileo-colonic region of the GIT in the treatment of ulcerative
colitis.
Contrast-induced Nephropathy in Non-cardiac Vascular Procedures, A Narrative Review: Part 1
Authors: Raffort Juliette , Lareyre Fabien , Katsiki Niki , Mikhailidis Dimitri P. 
Published: July 2021

:
Contrast-induced nephropathy (CIN) is animportant complication of iodinated contrast
medium (CM) administration, being associated with both short- and long-term adverse outcomes
(e.g. cardiorenal events, longer hospital stay and mortality). CIN has been mainly studied in relation
to cardiac procedures but it can also occur following non-cardiac vascular interventions. This
is Part 1 of a narrative review summarizing the available literature on CIN after non-cardiac vascular
diagnostic or therapeutic procedures for aortic aneurysm and carotid stenosis. We discuss the
definition, pathophysiology, incidence, risk factors, biomarkers and consequences of CIN in these
settings, as well as preventive strategies and alternatives to limit iodinated CM use. Physicians and
vascular surgeons should be aware of CM-related adverse events and the potential strategies to
avoid it. Clearly, more research in this important field is required.
Impact of COVID-19 on Gender Equality, Sexual and Reproductive Health Rights of Adolescent Girls and Young Women: A Narrative Review
Authors: Kumar Naina , Singh Amit Kant 
Published: July 2021

:
Adolescent girls and young women constitute a vulnerable population worldwide and an easy target to secondary impacts of a pandemic due to societal norms, existing age, gender-based inequalities, leading to a condition known as “second pandemic”. Due to local and national lockdowns to prevent coronavirus spread, educational institutions, workplaces, and health services have been shut down, making adolescent girls and women prone to sexual, physical exploitation, gender-based violence, educational, financial loss, lack of sexual and reproductive services. The present review briefs some of these secondary impacts of the COVID-19 pandemic on adolescent girls and women, which, if taken care of, can prevent many long-term consequences.

Methodology:
The literature was searched from governmental, non-governmental sites and agencies like WHO, UN, UNICEF, Guttmacher Institute, International Labor Organization, and English peer-reviewed journals, using the USA National Library of Medicine (Pubmed) database, the regional portal of Virtual Health Library, and Scientific Electronic Library Online. The data from the onset of the COVID-19 pandemic till March 2021 about the impact of COVID-19 on women and children were searched and studied. The descriptors used were school drop-out children, adolescent girls, women suffering at home/work, unmet need for contraception, unwanted pregnancies, unsafe abortion, child marriages, and female genital mutilation.

Results and Conclusion:
COVID-19 pandemic has resulted in a “hidden pandemic” against women and children. There is a skyrocketing rise in violence against women/girls, teenage pregnancies, school drop-outs, child marriages, abuse, and female genital mutilation. Hence, women and adolescent girls should be protected from the shadowing effects of the pandemic.