bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of a Mobile Transdiagnostic Emotion Regulation Intervention for University Students: A Micro‐Randomized Trial
Authors: Laure Tajda , Remmerswaal Danielle , Konigorski Stefan , Engels Rutger C. M. E. , Boffo Marilisa 
Published: December 2024

ABSTRACTIncreasing mental health problems among university students highlight the need for scalable, effective solutions. We have developed a transdiagnostic mobile intervention called ROOM, promoting adaptive emotion regulation (ER) skills among university students. Understanding how the intervention works and optimising content and delivery is essential for creating an effective and adaptive system. Therefore, this study aimed to optimise ROOM through a sequential explanatory mixed‐methods design, combining a Micro‐Randomized Trial (MRT), evaluating within‐person effects using repeated randomisation, with user experience interviews. 161 university students (82% females) participated in a 3‐week MRT to assess the intervention proximal outcomes, that is, participants' positive and negative emotional states after completing intervention exercises. Additionally, we evaluated impact on distal outcomes (i.e., distress symptoms and ER skills), and user experience by combining objective (e.g., exercise completion rates) and subjective (e.g., exercise likability and helpfulness ratings) engagement patterns with insights from the semi‐structured interviews (n = 18). Upon receiving the intervention, positive emotional states increased and negative ones decreased. The effect on positive emotional states gradually decreased over time while the effect on negative emotional states remained stable throughout the 3‐week intervention period. Distress symptoms and ER skills either remained stable or improved over the 3 weeks, which indicated the intervention's safety. Overall, engagement patterns and interview data show that the intervention was well received, students enjoyed this study design and found context‐sensitive content recommendations highly relevant.
Heterogeneity During the Formation of Waterborne Barrier Coating Revealed by Cryogenic Transmission Electron Microscopy
Authors: Du Haiqin , Xu Yifan , Yan Qiangqiang , Liu Zhongqi , Drumright Ray , Zheng Chen , Zhang Zheng , Song Amy , Zhang Pilan , Cui Shiwen , Zhou Guangrong , Nie Zhihong , Xu Yifei 
Published: December 2024

AbstractImaging the film formation process of waterborne barrier coatings in situ with nanoscopic resolution is very challenging, which limits the understanding of the underlying mechanisms and rational design of the materials. Here this challenge is tackled using in situ cryogenic transmission electron microscopy (cryoTEM) in combination with electron tomography (cryoET), which allows 3D imaging of the process with <1 nm resolution. By monitoring the film formation process of poly(ethylene‐co‐methacrylic acid) (EMAA) ionomer dispersion, onion‐like nano‐aggregates are captured. These aggregates can be removed by weakening the interactions between EMAA particles via adding amino alcohol coalescing agents or increasing the EMAA neutralization degree, which improves the barrier property of the coating simultaneously, indicating the importance of these heterogeneities to the material performance. The study benefits a better understanding of the formation kinetics of waterborne coatings, and demonstrates cryoTEM as an efficient method for studying the film formation process in situ.
A fiber‐based deterioration modeling framework for reinforced concrete structures subject to spatially non‐uniform corrosion patterns described by limited information
Authors: Bernardini Davide , Ruta Daniela , Di Re Paolo , Paolone Achille 
Published: December 2024

AbstractReinforced concrete structures are often subject to significantly non‐uniform corrosion patterns. In real situations, the information available about deterioration is incomplete and sometimes is reduced to qualitative judgments formulated by inspectors based on in‐situ surveys. This work proposes a practice‐oriented fiber‐based modeling approach capable to model arbitrary spatial distributions of corrosion characterized by limited information. The approach is based on the partition of the structure into pieces, regions and zones and by the use of degradation laws for material parameters. Local and global deterioration scales are introduced to facilitate consistent specification of material parameters on the basis of qualitative judgments. The penetration of deterioration beyond the exposed surfaces is modeled by the concepts of exposition zone and deterioration attenuation laws. The approach has been implemented in a macroelement of arbitrarily corroded beam‐column in OpenseesPy and validated by comparison with 16 experimental tests of columns with different section types, corrosion intensities, axial load and confinement levels. Results show that strength and ultimate drift can be predicted with remarkable accuracy.
When MNC Subsidiaries Are Caught in a Political Crisis: The Case of Mozambique
Authors: Finocchi Emiliano , Mudambi Susan M. , Oetzel Jennifer , Feinberg Susan 
Published: December 2024

ABSTRACTIn political crises, subsidiary‐level managers of multinational corporations (MNCs) face critical decisions around managing investment risk. Given the potentially existential threat posed by political crises, this study examines subsidiary responses to political risk. The focus is on the effect of firm crisis experience, threat perception, and managerial social embeddedness on the stay‐or‐exit decisions. With data from senior managers of 107 MNCs in Mozambique, we test three hypotheses. We find that the crisis experience of the MNC is a significant predictor of managers' threat perceptions (H1). While threat perception positively affects the likelihood of subsidiary exit (H2), the social embeddedness of the subsidiary manager dampens that relationship (H3). Threat perception does not necessarily drive exit likelihood, as subsidiaries led by socially embedded managers with high levels of social interactions with Mozambican and foreign friends are less likely to exit. These findings contribute to the literature on subsidiary‐level political risk management and underscore the significance of social embeddedness and crisis experience in shaping subsidiary resilience to political instability. For managers, these results highlight the value of fostering strong local networks and crafting flexible risk management strategies. Such insights are crucial for navigating the complexities of international markets during political turmoil.
Lead Mediated Lipopolysaccharides Exacerbates Fatty Liver Processes in High‐Fat Diets‐Induced Mice
Authors: Nie Penghui , Hu Liehai , You Tao , Jia Tiantian , Xu Hengyi 
Published: December 2024

ABSTRACTObesity leads to a variety of health risks, and lead, which is ranked second in Agency for Toxic Substances and Disease Registry's priority list of harmful substances, may be more harmful to individuals that are obese. C57BL/6 mice were fed a normal diet or a high‐fat diet with or without exposure to 1 g/L lead exposure in drinking water for 8 consecutive weeks. Serum and hepatic biochemistry analysis, histopathological observation, and RT‐qPCR were used to explore the potential mechanism of liver damage in obese individuals after Pb exposure, and fecal microbiota transplantation was performed to investigate the role of the gut microbiota in the progression of fatty liver disease. We found that the progression of fatty liver disease induced by high‐fat diets was accelerated by chronic lead intake. In addition, the occurrences of liver injury in recipient mice suggested the role of the gut microbiota. These findings indicated that the combination of lead and a HFD exacerbated hepatic lipotoxicity by activating LPS‐mediated inflammation, and that gut microbiota disorders and impaired intestinal barrier function play pivotal roles in the progression of fatty liver disease.
Advances in posterity of visualization in paradigm of nano‐level ultra‐structures for nano–bio interaction studies
Authors: Ghosh Aishee , Gupta Abha , Jena Snehasmita , Kirti Apoorv , Choudhury Anmol , Saha Utsa , Sinha Adrija , Kumari Shalini , Kujawska Małgorzata , Kaushik Ajeet , Verma Suresh K. 
Published: December 2024

AbstractThe progression in contemporary scientific field is facilitated by a multitude of sophisticated and cutting‐edge methodologies that are employed for various research purposes. Among these methodologies, microscopy stands out as a fundamental and essential technique utilized in scientific investigations. Moreover, due to the continuous evolution and enhancement of microscopic methodologies, nanotechnology has reached a highly developed stage within modern scientific realm, particularly renowned for its wide‐ranging applications in the fields of biomedicine and environmental science. When it comes to conducting comprehensive and in‐depth experimental analyses to explore the nanotechnological aspects relevant to biological applications, the concept of nano–biological interaction emerges as the focal point of any research initiative. Nonetheless, this particular study necessitates a meticulous approach toward imaging and visualization at diverse magnification levels to ensure accurate observations and interpretations. It is widely acknowledged that modern microscopy has emerged as a sophisticated and invaluable instrument in this regard. This review aims to provide a comprehensive discussion on the progress made in microscopic techniques specifically tailored for visualizing the interactions between nanostructures and biological entities, thereby facilitating the exploration of the practical applications of nanotechnology in the realm of biological sciences.
Effects of Amino Acid Supplementation on the Growth Performance of Broiler Chicks Challenged With Coccidiosis: A Meta‐Analysis
Authors: Izadi Yazdanabadi Fatemeh , Moghaddam Gholamali , Abbasabadi Mehdi , Akbari Mohsen , Mohammadi Bahram Satlikh , Khosravi Parvin , Sabzekar Hossein , Farrokhi Reza 
Published: December 2024

ABSTRACTThis meta‐analysis aimed to evaluate the effects of amino acid supplementation on the growth performance of broiler chicks challenged with coccidiosis. Data were collected on authorship, publication year, study sample characteristics and outcomes of interest related to growth performance. Effect sizes were calculated for both overall effects and the individual effects of each amino acid. The effects of moderator factors, such as supplementation levels and duration, were also assessed, and bias was calculated. Works were obtained from PubMed, Elsevier, ScienceDirect, Wiley, Springer Link and Scopus databases, with the help of search engines like Google Scholar and ResearchGate, covering the period from 2013 to 2023. A random‐effects model was used. Thirteen works were included in the current analysis, examining the effects of arginine (n = 4), methionine (n = 6), threonine (n = 3) and glutamine (n = 3). Amino acid supplementation [0.326, CI 95% (0.297–0.355); p = 0.000], arginine [0.430, CI 95% (0.293–0.568); p = 0.000] and threonine [0.793, CI 95% (0.193–1.38); p = 0.009] significantly increased body weight. Amino acid supplementation [0.052, CI 95% (0.022–0.081); p = 0.000] and arginine [0.317, CI 95% (0.049–0.585); p = 0.000] also significantly increased feed intake. Higher levels of amino acids (≥1.50%) and longer supplementation periods (≥15 days) significantly increased body weight and feed intake, while reducing the feed conversion ratio. Funnel plots, fail‐safe N and Egger tests showed no evidence of bias. In conclusion, arginine supplementation has the potential to increase body weight and feed intake in poultry challenged with coccidiosis. Higher doses of amino acids and longer supplementation periods are recommended in such cases.
Excessive haemorrhage in a Great Dane with suspected von Willebrand disease following two routine corrective eyelid surgeries
Authors: Bekkat‐Berkani Desislava , Raszplewicz Joanna , Duffy Natalie 
Published: December 2024

AbstractA 7‐month‐old, male, entire Great Dane was presented for surgical treatment of bilateral scrolled cartilage abnormality of the nictitating membranes with concurrent macroblepharon and early‐entropion complex. The patient underwent two separate surgical interventions and experienced excessive haemorrhage, which was difficult to control after both procedures. A reduction in haemorrhage was observed following the administration of desmopressin acetate infusion. Von Willebrand disease type I was strongly suspected. This report discusses the importance of functional coagulation testing in contrast to reliance on results of prothrombin time and activated partial thromboplastin time clotting assays alone in diagnosing the underlying cause of prolonged surgical haemorrhage in dogs, particularly in breeds with hereditary coagulation disorders. It provides a brief summary on primary and secondary haemostasis, causes for delayed surgical haemorrhage and possible treatment options.
Healthcare Professionals' Experiences From the COVID‐19 Vaccination Program for the Homebound Population in Greece: A Cross‐Sectional Mixed‐Methods National Study
Authors: Papageorgiou Dimitra Iosifina , Vlachopoulos Nikolaos , Gavana Magda , Tahtalidou Zoi , Gialama Marilena , Avakian Ioanna , Ntenta Panagiota , Theodoropoulos Elias , Andreou Martha , Evangelidis Paschalis , Evangelidis Nikolaos , Nteli Despoina , Nteli Maria , Vitoris Ioannis , Avramidou Eleni , Nastas Theofilos , Bapka Aspasia , Zgouridou Aikaterini , Kokkali Stamatia , Ploukou Stella , Symintiridou Despoina , Paganas Aristofanis , Zeimbekis Doukas , Dandoulakis Michael , Giakoumis Anastasios , Haidich Anna Bettina , Smyrnakis Emmanouil 
Published: December 2024

ABSTRACTDuring the pandemic, mobile vaccination units administered COVID‐19 shots to homebound populations. This study explores the perspectives of public healthcare providers involved in Greece's COVID‐19 home vaccination program, aiming to identify challenges and inform improvements in delivering healthcare services at home. This is a cross‐sectional mixed‐methods survey with convergent design, conducted in public Primary Health Care facilities, using a questionnaire. Facilities from all Health Districts were invited. The study population included healthcare professionals and administrative staff engaged in vaccination units. Data were collected from April to July 2022. Quantitative data were analyzed using descriptive statistics and univariate linear regression analysis, while qualitative data underwent thematic analysis. Integration at the analysis phase enhanced understanding and reliability. The study was approved by the Bioethics Committee of the Aristotle University of Thessaloniki. A total of 1200 participants from 168 facilities across six Health Districts responded. The majority were nurses (34.1%) and general practitioners (24.7%). Participants unanimously praised the program's concept, aligning it with Primary Health Care and expressed readiness for future involvement, but reported time constraints. Those in larger groups found time management easier (1.68, 95% CI [1.28, 2.20], p < 0.001). Thematic analysis of 1070 text responses identified five themes, including guidance for implementation, resource availability, field challenges, professionals' skillsets, and public engagement. Collaboration with colleagues and authorities to address transportation problems proved vital for success. Understaffing and time constraints were evident. Integrating a new service into busy settings poses challenges, underscoring the need for problem‐solving and empowering healthcare personnel to address shortcomings.
Gleichwertige Lebensverhältnisse: was wir wissen und was nicht
Authors: Lorenz Astrid , Pischtschan Luisa 
Published: December 2024

ZusammenfassungIn einer Demokratie ist die Politik „responsiv“ gegenüber der Gesellschaft, d. h. sie reagiert auf deren Wünsche, Vorstellungen und Bedürfnisse. Dies ist eine Grundannahme der Demokratieforschung. Besonders für die in einer Verfassung genannten Anliegen sollte die Responsivitätsannahme zutreffen. Empirisch geprüft wurde dies aber bislang kaum für das in Deutschland verankerte Leitbild, gleichwertige Lebensverhältnisse zu gewährleisten. Wie wir in diesem Kapitel zeigen, ist der Wissensstand, an den Studien zu gleichwertigen Lebensverhältnissen anschließen können, beträchtlich, aber es bedarf mehr Forschung dazu, welche Themen Menschen bei der Beschreibung des Lebens vor Ort bewegen, was sie sich unter gleichwertigen Lebensverhältnissen vorstellen und was sie sich von der Politik wünschen. Zugleich liefert das Kapitel Informationen zur Politik gleichwertiger Lebensverhältnisse in Deutschland, die dabei helfen, die Ergebnisse der nachfolgenden Analyse einzuordnen, und eine Begründung unseres spezifischen Untersuchungsansatzes.
Beschreibungen der lokalen Lebensverhältnisse
Authors: Lorenz Astrid , Pischtschan Luisa 
Published: December 2024

ZusammenfassungWie lebt es sich vor Ort in Deutschland? Was macht für Menschen ihren Ort aus? Das wollten wir im ersten Teil unserer Gruppendiskussionen von den Teilnehmern in den 24 ausgewählten Kommunen wissen. Wie wir in diesem Kapitel zeigen, beschrieben sie ihren Ort vor dem Hintergrund von Mobilität. Dies könnte ihre Wahrnehmung und Bewertung gleichwertiger Lebensverhältnisse beeinflussen (Abschn. 4.1). Überall zeichneten die Gruppen ein positives Bild vom eigenen Ort und erwähnten sehr ähnliche Aspekte als wichtig für das Leben dort. Dabei bestanden aber teilweise Unterschiede zwischen Großstädten und kleineren Orten hinsichtlich der konkreten Inhalte, die angesprochen wurden (Abschn. 4.2). Die im Nachgang zu den Gruppendiskussionen durchgeführte anonyme Befragung der Teilnehmer bestätigte die überwiegend positive Darstellung des Lebens vor Ort (Abschn. 4.3).
Harnessing Trichoderma Mycoparasitism as a Tool in the Management of Soil Dwelling Plant Pathogens
Authors: Singh Srishti , Singh Alok Kumar , Pradhan Bhubaneswar , Tripathi Sudipta , Kumar Kewat Sanjay , Chand Sasmita , Rout Prangya Ranjan , Shahid Muhammad Kashif 
Published: December 2024

AbstractMaintaining and enhancing agricultural productivity for food security while preserving the ecology and environment from the harmful effects of toxicants is the main challenge in modern monoculture farming systems. Microbial biological agents can be a promising substitute for traditional synthetic pesticides to manage plant diseases. Trichoderma spp. are soil-dwelling ascomycete fungi and are common biocontrol agents against diverse phytopathogens. Trichoderma-based biocontrol techniques can regulate and control soil-borne plant diseases through mechanisms such as mycoparasitism, the production of antibiotics and hydrolytic enzymes, rhizo-sphere competence, the effective competition for available resources, induction of plant resistance and facilitation of plant growth. Numerous secondary metabolites produced by Trichoderma spp. are reported to prevent the development of soil-borne plant disease. Thus, Trichoderma spp. may have direct and indirect biological impacts on the targeted plant pathogens. Furthermore, this review discusses the convenient implications and challenges of applying Trichoderma-based strategies in agricultural settings. Overall, the assessment underscores the potential of Trichoderma as a sustainable and effective tool for mitigating soil-borne pathogens, highlighting avenues for future research and applications.
Local anaesthesia vs. brachial plexus block in trapeziometacarpal joint arthroplasty
Authors: Moshammer Maximilian , Klim Sebastian Martin , Glehr Reingard , Hauer Georg , Hecker Andrzej , Leithner Andreas , Glehr Mathias 
Published: December 2024

Abstract
Introduction
An established anaesthetic procedure used during total trapeziometacarpal joint (TMCJ) arthroplasty is the brachial plexus block (BPB). It was hypothesized that local anaesthesia (LA) provides advantages in overall cost, enables intraoperative assessment of the prosthesis, and minimises the anaesthetic risk. In this study, LA to BPB was compared and outcomes, safety, and overall patient satisfaction were analyzed.

Materials and methods
In this single-center cohort study, 32 patients (34 operated thumbs) who underwent total TMCJ arthroplasty between February 2018 and July 2021 were included. Two groups were formed depending on the anaesthetic method used. One group was operated under LA, and the other under BPB. Functionality scores were assessed preoperatively and three month postoperatively. Additionally, pain was assessed on the 1st and 12th postoperative day. Data on intraoperative pain and anxiety, overall satisfaction, pain medication use, and willingness to undergo the procedure again were gathered through a retrospective telephone survey.

Results
No significant differences between LA and BPB were found in terms of functional outcomes, pain reduction, and willingness to repeat the procedure. The analysis further showed significant differences in intraoperative anxiety (higher in the LA group; LA 1.69, SD: 2.65; BPB 0.28, SD: 0.58; measured using a numeric rating scale 0–10; p = 0.045), operation length (higher in BPB group; LA 39 min, SD: 7.46; BPB 45 min, SD: 7.02; p = 0.018) and overall setup time (higher in BPB group; LA 76 min, SD: 15.85; BPB 102 min, SD: 19.66; p < 0.001). No conversion from LA to another anaesthetic method was necessary.

Conclusion
The use of LA in total TMCJ arthroplasty is a practical and reliable alternative to the well-established BPB. LA reduces the cost of the procedure, necessity of an anaesthesiology team and the duration of the patients´ hospital stay. Patients should be actively involved in selecting the anaesthetic method to optimize the operative procedure and overall outcome.
Risk analyses for perioperative morbidities after aseptic knee revision arthroplasty
Authors: Abdelghany Ahmed , Migliorini Filippo , Peterlein Christian , Götze Christian , Koettnitz Julian 
Published: December 2024

Abstract
Introduction
Total lower limb arthroplasties are standard orthopedic surgeries that are steadily increasing in modern civilization. In proportion, the number of revision arthroplasties and the corresponding financial burden for healthcare systems will increase. The present clinical investigation analyzed morbidities after aseptic revision knee arthroplasty.

Methods
Data from 122 patients following aseptic revision TKA (total knee arthroplasty) were collected. The study collected information on systemic and surgical complications during hospitalization and follow-up, blood transfusion units, and changes in Hb and CRP levels. Hb and CRP were measured preoperatively and on postoperative days 1, 2, and 4. Statistical analyses were performed using IBM SPSS version 29.

Results
Significant differences were observed in systemic, surgery-related and blood transfusion rates and reasons for knee replacement changes based on age and gender. Of the patients, 38.5% received a full component change, 11.5% received a partial component replacement (either femoral or tibial), 30.3% had an isolated inlay change, and 19.7% underwent debridement only. Femoral and tibial loosening were more frequent in patients over 75 years and those with longer intervals between the initial operation and re-presentation (p = 0.001). Patients with movement deficits and malposition presented earlier for consultation (p = 0.02). Prolonged high CRP levels were significantly correlated with systemic complications, longer hospital stays, and extended operative times.

Conclusions
Aseptic knee revision arthroplasty is a complex procedure with perioperative morbidities that can significantly impact outcomes. Age and gender are crucial factors in managing complications during hospitalization and follow-up. Elderly patients, particularly those over 75 years, are more prone to aseptic loosening and require tailored preoperative preparation. The study underscores the importance of individualized patient care strategies to mitigate risks and improve outcomes in aseptic knee revision arthroplasty.
Trial registration: Not applicable.