bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Maternal Postpartum Quality of Life Instrument (MPQOLI): Development and Psychometric Evaluation in an Exploratory Sequential Mixed-Method Study
Authors: Mokhtarian-Gilani Tahereh , Kariman Nourossadat , Nia Hamid Sharif , Doulabi Mahbobeh Ahmadi , Nasiri Malihe 
Published: January 2021

Abstract
Background and Objective: There is no comprehensive instrument for the assessment of postpartum quality of life (QOL). This study was conducted to develop the Maternal Postpartum Quality of Life Instrument (MPQOLI) and assess its psychometric properties.Materials and Methods: This methodological study was conducted in 2019–2020 using an exploratory sequential mixed-method design. A qualitative study and a literature review were conducted to generate MPQOLI items. Through purposeful sampling, 590 postpartum women were recruited to respond the instrument. Face and content validity were assessed qualitatively and quantitatively and construct validity was assessed through exploratory and confirmatory factor analyses and convergent and discriminant validity assessments. Reliability was also assessed through different methods, including Cronbach’s alpha and McDonald’s Omega.Results: Eight items were deleted in content validity assessments and eighteen items were deleted in item analysis. Participants responded the 31-item MPQOLI. During exploratory factor analysis, fifteen items were deleted and the remaining sixteen items were loaded on five factors labeled perceived support, sexual relationship, bonding with newborn, breastfeeding and newborn care, and satisfaction with postpartum transition. These five factors explained 53.26% of the total variance. Confirmatory factor analysis confirmed the five-factor structure of MPQOLI with a CMIN/DF of 2.192, an RMSEA of 0.057, a χ2 of 206.087, a PCFI of 0.738, a PNFI of 0.705, a CFI of 0.942, and an IFI of 0.943. Average variance extracted was more than 0.5 and more than maximum shared squared variance, confirming convergent and discriminant validity, respectively. Reliability was also confirmed with Cronbach’s alpha values of 0.70–0.907 and an intraclass correlation coefficient of 0.919.Conclusion: The sixteen-item MPQOLI is a valid and reliable instrument for postpartum QOL assessment. It includes items on the different aspects of postpartum QOL and can be used for the early diagnosis of impaired postpartum QOL. Further studies are needed to assess the psychometric properties of MPQOLI in different cultures and communities.
The Differential Urine Proteome Analysis of a Ventilator-induced Lung Injury Rat Model by Label-free Quantitative and Parallel Reaction Monitoring Proteomics
Authors: Qin Weiwei , Zhang Xiao , Chen Lingnan , Li Qiujie , Zhang Benwang , Sun Lixin , Han Wei 
Published: January 2021

Abstract
Background: Urine is a promising resource for biomarker research. Therefore, the purpose of this study was to investigate potential urinary biomarkers to monitor the disease activity of ventilator-induced lung injury (VILI). Methods: In the discovery phase, a label-free data-dependent acquisition (DDA) quantitative proteomics method was used to profile the urinary proteomes of VILI rats. For further validation, the differential proteins were verified by parallel reaction monitoring (PRM)-targeted quantitative proteomics.Results: In all, 727 high-confidence proteins were identified with at least 1 unique peptide (FDR ≤1%). Compared to the control group, 110 proteins (65 upregulated, 45 downregulated) were significantly changed in the VILI group (1.5-fold change, P<0.05). The canonical pathways and protein-protein interaction analyses revealed that the differentially expressed proteins were enriched in multiple functions, including oxidative stress and inflammatory responses. Finally, thirteen proteins were identified as candidate biomarkers for VILI by PRM validation. Among these PRM-validated proteins, AMPN, MEP1B, LYSC1, DPP4 and CYC were previously reported as lung-associated disease biomarkers. SLC31, MEP1A, S15A2, NHRF1, XPP2, GGT1, HEXA, and ATPB were newly discovered in this study. Conclusions: Our results suggest that the urinary proteome might reflect the pathophysiological changes associated with VILI. These differential proteins are potential urinary biomarkers for the activity of VILI.
An Outbreak Investigation of Burkholderia Cepacia Infections Related With Contaminated Chlorhexidine Mouthwash Solution in a Tertiary Care Center in Turkey.
Authors: Bilgin Huseyin , Gelmez Gülşen Altınkanat , Bayrakdar Fatma , Sayın Elvan , Gül Fethi , Pazar Nazlı , Culha Gulcan , Yildiz Serap Suzuk , Cinel İsmail , Korten Volkan 
Published: January 2021

Abstract
Background: We report a nosocomial outbreak caused by Burkholderia cepacia that occurred among six patients admitted in the medical and surgical intensive care unit between 04 March 2019 and 02 April 2019 in Istanbul, Turkey. Methods: The outbreak investigation was launched on 11 March 2019 five days after the detection of B. cepacia in four different patients. We defined potential reservoirs and started environmental screening. We sampled the liquid solutions used in patient care activities. Pulse-field gel electrophoresis (PFGE) was performed to determine the genetic relatedness of environmental and patient samples.Results: B. cepacia was isolated in tracheal aspiration cultures of six patients. Three out of six patients developed healthcare-associated pneumoniae due to B. cepacia. Environmental cultures in the ICUs revealed B. cepacia growth in 2% chlorhexidine-gluconate mouthwash solution that been used in the colonized patients as well as in samples obtained from the unused products. PFGE revealed the patient and a specific batch of chlorhexidine mouthwash solution samples had a 96% similarity. Conclusion: Contamination of medical solutions used in critical patient care could cause outbreaks and should be detected early by infection control teams.
COVID-19 Screening By Anti-SARS-CoV-2 Antibody Seropositivity: Clinical And Epidemiological Characteristics, Comorbidities, And Food Intake Quality
Authors: Macedo-Ojeda G , Muñoz-Valle JF , Yokogawa-Teraoka P , Machado-Sulbarán AC , Loza-Rojas MG , Arredondo AC García , Tejeda-Constantini R , Vega-Magaña AN , González-Estevez G , García-Chagollán M , Zepeda-Nuño JS , Hernández-Bello J 
Published: January 2021

Abstract

Background: Developing countries have reported lower molecular diagnostic testing levels due to a lack of infrastructure and resources. Therefore, antibody tests represent an alternative to detect exposure to SARS-CoV-2 and analyze possible risk factors in them. This study aimed to describe and compare the clinical and epidemiological characteristics and the quality of food intake between individuals with a positive or negative test to antibodies against SARS-CoV-2.Methods: Mexican individuals of diverse ages and sex, that attended to detect anti-SARS-CoV-2 antibody seropositivity from July to November 2020 were included. A survey was applied to identify the clinical and epidemiological characteristics and food intake quality in negative and positive individuals for anti-SARS-CoV-2 antibodies. These variables were compared using the Chi-square test, Kruskal Wallis, Fisher's exact test, or t-student.Results: In this study, a total of 1,799 individuals participated; 42% were positive for SARS-CoV-2. It was found that seropositive subjects were older and that diabetes was more prevalent in them (p <0.01). No differences were identified in the blood type nor vaccination against influenza between seronegative and seropositive cases. Cough, respiratory distress, muscle pain, joint pain, and anosmia were more prevalent in seropositive cases than in those seronegative (p<0.0001). The IgM or IgM+IgG seropositive cases presented anosmia more frequently than those with only IgG antibodies (p<0.05). The dietary patterns and individual food intake habits were similar in both groups, except for the most consumed type of fat (p = 0.006). Seronegative cases showed to consume monounsaturated fats more frequently than other types of fats, whereas seropositive subjects have more regular consumption of polyunsaturated fats.Conclusion: This study confirms the association between being anti-SARS-CoV-2 seropositive with older age and the presence of diabetes mellitus. Furthermore, it suggests muscle and joint pain could also be considered major criteria for discriminating patients with suspected COVID-19 seropositivity. Moreover, the results suggested polyunsaturated fats as a possible new risk factor associated with COVID-19, and anosmia as a marker of active disease. This finding will be of interest to investigate in further studies regarding the type of fat consumed and the risk of infection by SARS-CoV-2.
New insights into Oniscidea (Crustacea: Isopoda) mitogenome structural features and phylogenetic placement of targeted taxa using mitogenomic and nuclear data
Authors: Yang Lina , Chen Ruru , Zhang Rui , Dimitriou Andreas C. , An Jianmei 
Published: January 2021

Abstract
Among Isopoda suborders the Oniscidea has the highest species richness, and is also the largest terrestrial group in the Crustacea. Terrestrial isopods are an excellent case to study adaptations related to sea-land transition. However, the monophyly of Oniscidea and the relationships of the main lineages has been debated over the last three decades. Aiming to further explore structural features of mitochondrial genome and investigate the phylogenetic relationships within Oniscidea, the mitogenomes and a series of nuclear markers of the oniscids Ligia exotica and Mongoloniscus sinensis were sequenced. The nuclear genome was represented by four nuclear genes analyzed in a separate dataset. The mitogenomes of L. exotica and M. sinensis were 16,018 and 14,978 bp in length, respectively. Both included 13 protein-coding genes, 2 rRNA genes, and 21 and 19 tRNA genes respectively, missing one and three tRNA genes respectively compared to the isopod ground pattern. The M. sinensis mitogenome had higher average A+T content (~75.3%) than any other isopod studied to date. Phylogenetic analyses confirmed the assignment of M. sinesis to Agnaridae, as well as the sister-group relationship of the family with Porcellionidae, one of the more derived Crinochaeta clades. On the other hand, the basal position of Ligia within Oniscidea and the close evolutionary relationship with the aquatic groups Valvifera, Shaperomatida and some Cymothoidea that were included in our analysis, is indicated.
Long-term health-related quality of life and burden of disease after intensive care: Development of a patient-reported outcome measure.
Authors: Malmgren Johan A , Waldenström Ann-Charlotte , Rylander Christian , Johannesson Elias , Lundin Stefan 
Published: January 2021

Abstract
BackgroundICU survivorship includes a diverse burden of disease. Current questionnaires used for collecting information about health-related problems and their relation to quality of life lack detailed questions in several areas relevant to ICU survivors. Our aim was to construct a provisional questionnaire on health-related issues based on interviews with ICU survivors and to test if this questionnaire was able to show differences between ICU survivors and a control group.MethodsThirty-two ICU survivors were identified at a post-ICU clinic and interviewed at least six months after ICU discharge. Using an established qualitative methodology from oncology, all dysfunctions and disabilities were extracted, rephrased as questions and compiled into a provisional questionnaire. In a second part, this questionnaire was tested on ICU survivors and controls. Inclusion criteria for the ICU survivors were ICU stay at least 72 hours with ICU discharge six months to three years prior to the study. A non-ICU treated control group was obtained from the Swedish Population Register, matched for age and sex. Eligible participants received an invitation letter and were contacted by phone. If willing to participate, they were sent the questionnaire. Descriptive statistics were applied.ResultsAnalysis of the interviews yielded 238 questions in 13 domains: cognition, fatigue, physical health, pain, psychological health, activities of daily life, sleep, appetite and alcohol, sexual health, sensory functions, gastrointestinal functions, urinary functions and work life.In the second part, 395 of 518 ICU survivors and 197 of 231 controls returned a completed questionnaire, the response rates being 76.2% and 85.3% respectively. The two groups differed significantly in 13 of 22 comorbidities. ICU survivors differed in a majority of questions (p ≤ 0.05) distributed over all 13 domains compared with controls.ConclusionsThis study describes the development of a provisional questionnaire to identify health-related quality of life issues and long-term burden of disease after intensive care.The questionnaire was answered by 395 ICU survivors. The questionnaire could identify that they experience severe difficulties in a wide range of domains compared with a control group.Trial registrationClinicalTrials.gov Ref# NCT 02767180
Personality traits predict regression of pelvic girdle pain after pregnancy: a longitudinal follow-up study.
Authors: Xiangsheng Tang , Long Gong , Yingying Shi , Xiao An , Ping Yi , Mingsheng Tan 
Published: January 2021

Abstract
Background: Pelvic girdle pain (PGP) is a multifactorial condition with a partly unknown etiology. This condition can be mentally and physically compromising both during and after pregnancy. To provide all-around preventive measures to improve the recovery from PGP, it is a necessity for obstetricians and orthopaedists to develop predictive studies about the worse prognosis for this condition. Therefore, this study aims to determine whether personality traits can predict the consequences of long-term pregnancy-related PGP.Methods: This was a prospective study conducted from January 2015 to August 2018. A total of 387 pregnant women were enrolled in this study. According to whether they had experienced PGP during the past four weeks, the subjects were classified into no PGP and PGP groups. Persistent PGP after the pregnancy was deﬁned as a recurrent or continuous visual analog score (VAS) pain rating of ≥ 3 for more than one week. The Quick Big Five Personality Test (QBFPT) was used to assess personality traits. Data were obtained by mail or in the clinic. The authors collected data including age, BMI, educational level, annual household income, cesarean delivery, breastfeeding, unexpected sex of the baby, parity, sick leave, no or rare ability to take rest breaks at work, and PGP in the previous pregnancy. Results: Of 387 included women, 264 subjects experienced PGP during the pregnancy with a mean age of 26.3 ± 4.5 years. A total of 80 of 264 (30.3%) women experienced persistent PGP after the pregnancy. Persistent PGP after the pregnancy was associated with higher levels of neuroticism (OR= 2.12, P=0.001). Comparing women with persistent PGP, those who reported higher levels of extraversion and conscientiousness were more likely to recover from this condition (OR=0.65, P = 0.001; OR= 0.82, P = 0.01, respectively). Besides, neuroticism was positively associated with higher pain scores (r=0.52, P=0.005). However, extraversion and conscientiousness domains showed negative correlations with pain score (r=-0.48, P=0.003; r=-0.36, P=0.001).Conclusions: Personality traits were significantly associated with the outcomes of PGP.
A comparison of the analysis of methods for feature extraction and classification by Wavelet transform in SSVEP BCIs
Authors: Heidari Hoda , einalou zahra , Dadgostar Mehrdad , Hosseinzadeh Hamidreza 
Published: January 2021

Abstract
Most of the studies in the field of Brain-Computer Interface (BCI) based on electroencephalography have a wide range of applications. Extracting Steady State Visual Evoked Potential (SSVEP) is regarded as one of the most useful tools in BCI systems. In this study, different methods which includes 1) feature extraction with different spectral methods (Shannon entropy, skewness, kurtosis, mean, variance) and wavelet transform magnitude, 2) feature selection performed by various methods (decision tree, principle component analysis (PCA), t-test, Wilcoxon, Receiver operating characteristic (ROC)), 3) classification step applying k nearest neighbor (k-NN), support vector machines (SVM), Bayesian, multiple layer perceptron (MLP) were compared from the whole stream of signal processing. Through combining such methods, the effective overview of the study indicated the accuracy of classical methods. In addition, the present study relied on a rather new feature selection described by decision tree and PCA, which is used for the BCI-SSVEP systems. Finally, the obtained accuracies were calculated based on the four recorded frequencies representing four directions including right, left, up, and down. The highest level of accuracy was obtained 91.39%.
Impact of Haemophilus influenzae type b combination vaccination on asthma symptoms and pneumonia in 5-year-old children in rural Bangladesh: A longitudinal study and comparison with a previous cross-sectional study
Authors: TAKEUCHI HARUKO , Hasan S. M. Tafsir , Zaman Khalequ , Takanashi Sayaka , Hore Samar Kumar , Yeasmin Sultana , Ahmad Shaikh Meshbahuddin , Alam Md Jahangir , Jimba Masamine , Iwata Tsutomu , Khan Md Alfazal 
Published: January 2021

Abstract
Background: Although the prevalence of bronchial asthma has been increasing worldwide since the 1970’s, the prevalence among 5-year-old children was significantly lower in 2016 than in 2001 in rural Bangladesh. We aimed to determine whether the Haemophilus influenzae type b (Hib) combination vaccination (without booster) started in 2009 contributed to this decrease.Methods: A case-control study was conducted among 1658 randomly selected 5-year-old children from Matlab, Bangladesh. Data on wheezing were collected using the International Study of Asthma and Allergies in Childhood questionnaire. The vaccination data were collected from the records of the Matlab Health and Demographic Surveillance System, while data on pneumonia were obtained from the clinical records of Matlab Hospital. Adjusted odds ratios (aORs) were calculated for the risk for wheezing. The reduction rate was calculated to determine the impact of the vaccination on pneumonia history between the present study and our previous study conducted in 2001 by using the following formula: (percentage of pneumonia cases in 2001 - percentage of pneumonia cases in 2016)/(percentage of pneumonia cases in 2001) times 100 (%).Results: Hib combination vaccination was a protecting factor against wheezing (aOR: 0.50; p = 0.010), while pneumonia at 1, 2, 3–4 years of age were risk factors for wheezing (aOR: 2.86, 3.19, 2.86; p = 0.046, 0.030, 0.030, respectively). The history of pneumonia was significantly lower in the 2016 study participants than those in 2001 both in the overall cohort and the wheezing group (paired t-test: p = 0.012, p < 0.001, respectively). Whereas the history of pneumonia decreased when the children grew older in the 2001 overall cohort, it peaked at the age of 2 years in 2016 wheezing group. The reduction rate decreased when children grew older in both the overall cohort and the wheezing group, however, it decreased faster in the wheezing group.Conclusions: Hib combination vaccination was a protective factor against wheezing in 0-year-old children. However, the effects of vaccination might have attenuated at the ages of 1-4 years, because no booster dose was administered. The addition of a booster dose might further decrease the prevalence of asthma and wheezing.
Soil Quality Evaluation Under Different Land Use Types in Kersa Sub-watershed, Eastern Ethiopia
Authors: Tefera Yared Mulat , Tehaye kibebew Kibret , Bedadi Bobe Bobe , Kedir Muktar Mohammed 
Published: January 2021

Abstract
Background: Soil quality, which can be inferred using indicators that interact synergistically, is affected by land use types and agricultural management practices. This study assessed the status of soil quality under three adjacent land uses (cultivated, grazing, and fallow) in Kersa subwatershed (622 ha). Soil samples were collected from the surface soil (0-20 cm depth) of the identified land uses with three replications and the soil quality parameters were analyzed. A minimum data set of soil quality indicators were selected from physical, chemical, and biological parameters using the literature review and expert opinion method. Linear scoring functions were used to give the unitless scores for the selected data sets, which were then integrated into a soil quality index (SQI).Results: The results revealed that bulk density, aggregate stability, pH, cation exchange capacity (CEC), available P, and soil organic carbon (SOC) had a significant difference in SQI among the different land uses. The soil quality indices were 0.69 for grazing land, 0.62 for cultivated land, and 0.59 for the fallow land. The SQI of all the land uses falls in the intermediate soil quality (0.55 < SQI < 0.70) class.Conclusion: In almost all the quality indicators assessed, the grazing land was superior to the cultivated and fallow lands. Therefore, implementing management practices that enhance soil quality like organic matter-controlled systems is imperative for sustainable agricultural production in the study area.