bluuebunny/crossref_metadata_2025_split huggingface dataset:
What do stakeholders in the construction industry look for in non-financial disclosure and what do they get?
Authors: Hadro Dominika , Fijałkowska Justyna , Daszyńska-Żygadło Karolina , Zumente Ilze , Mjakuškina Svetlana 
Published: August 2021

Purpose
This study aims to verify whether non-financial disclosure in the construction industry (CI) responds to stakeholders’ information needs and explores the most frequent topics disclosed in terms of the environmental, social and governance (ESG) pillars.

Design/methodology/approach
This study uses a bag-of-words method and latent Dirichlet allocation to match stakeholders’ expectations with information disclosed by companies. This paper assesses the publicly available non-financial disclosure of the 46 European CI companies covered by the Refinitiv database with ESG scores.

Findings
This study provides two main findings. First, it shows the mismatch between stakeholders’ information needs and what they get in non-financial reporting. Despite non-financial information in CI disclosure, the information disclosed by many CI companies does not meet their users’ information needs. CI companies commonly focus on their sustainable products and health policy while omitting other topics of interest – the circular economy, unethical business behaviour, migrant policy and human trafficking. Second, this study indicates the defects of simple disclosure analysis based on keywords and highlights the importance of context in information analysis.

Practical implications
The proposed novel approach to text analysis offers several practical applications. It is a more effective tool for evaluating companies’ sustainability performance. It may be especially important to ESG rating providers. Additionally, the results may be of interest to companies wishing to improve their communication, and, in particular, to regulators and standard setters in two matters. The first is the need for more pressure to increase awareness among issuers to shift from disclosing large amounts of non-financial information to disclosing good quality non-financial information, which would be appropriate for meeting stakeholders’ expectations. The second is the necessity for deepening issuers’ understanding of the diverse stakeholders’ information needs, considering the substantial differences among industries and improving communication to meet them.

Originality/value
This study introduces text analysis that, apart from keywords, considers the context of these keywords’ appearances in a report’s narration. It allows a significantly improved understanding of the information disclosed and a more stable grounding for reasoning, leading to better and informed decisions. Moreover, this study verifies how the information disclosed matches stakeholders’ needs. Finally, it enriches the literature on sectoral analysis concerning non-financial disclosure.
Fatal bilateral pneumothoraces after electroacupuncture treatment: A case report and literature review
Authors: Yamaguchi Rutsuko , Makino Yohsuke , Torimitsu Suguru , Chiba Fumiko , Kihara Yuko , Iwase Hirotaro 
Published: August 2021

AbstractAcupuncture is practiced as a complementary medicine worldwide. Although it is considered a safe practice, pneumothorax is one of its most common serious complications. However, there have been few reports of deaths due to pneumothorax after acupuncture treatment, especially focused on electroacupuncture. We report an autopsy case of a man in his 60s who went into cardiopulmonary arrest and died immediately after receiving electroacupuncture. Postmortem computed tomography (PMCT) showed bilateral pneumothoraces, as well as the presence of numerous gold threads embedded subcutaneously. An autopsy revealed two ecchymoses in the right thoracic cavity and a pinhole injury on the lower lobe of the right lung, suggesting that the needles had penetrated the lung. There were marked emphysematous changes in the lung, suggesting that rupture of bullae might also have contributed to bilateral pneumothoraces and fatal outcome. The acupuncture needles may have been drawn deeper into the body than at the time of insertion due to electrical pulses and muscle contraction, indicating the need for careful determination of treatment indications and technical safety measures, such as fail‐safe mechanisms. This is the first case report of fatal bilateral pneumothoraces after electroacupuncture reported in the English literature. This case sheds light on the safety of electroacupuncture and the need for special care when administering it to patients with pulmonary disease who may be at a higher risk of pneumothorax. This is also the first report of three‐dimensional reconstructed PMCT images showing the whole‐body distribution of embedded gold acupuncture threads, which is unusual.
Per‐oral pancreatoscopy‐guided lithotripsy for the endoscopic management of pancreatolithiasis: A systematic review and meta‐analysis
Authors: Guzmán‐Calderón Edson , Martinez‐Moreno Belen , Casellas Juan A. , Aparicio José Ramón 
Published: August 2021

ObjectivePancreatic stones result from chronic pancreatitis and can occur in the main pancreatic duct, pancreatic branches or parenchyma. Although extracorporeal shock wave lithotripsy (ESWL) is considered the first‐line treatment, per‐oral pancreatoscopy (POP) has emerged as a useful method for treating pancreatic stones. The aim of this systematic review and meta‐analysis was to determine the efficacy and safety of POP‐guided lithotripsy, electrohydraulic lithotripsy (EHL) and laser lithotripsy (LL), in patients with pancreatolithiasis.MethodsLiterature review was conducted in PubMed, OVID, MEDLINE and Cochrane Library databases for studies published up to August 2020.ResultsAltogether 15 studies were analyzed, of which 11 were retrospective and four were prospective. The studies comprised 370 patients, of whom 66.4% were male. The patients underwent 218 EHL and 155 LL. The pooled technical and clinical success rate of the overall POP was 88.1% and 87.1%. For EHL‐POP, the pooled technical success rate was 90.9% (95% CI 87.2%‐95.2%) and the pooled clinical success rate was 89.8% (95% CI 87.2%‐95.2%). While for LL‐POP, the pooled technical and clinical success rate was 88.4% (95% CI 85.9%‐95.1%) and 85.8% (95% CI 80.6%‐91.6%). In total 43 adverse events occurred (12.1%; 95% CI 8.7%‐15.5%).ConclusionPOP‐guided lithotripsy has a high rate of technical and clinical success for managing pancreatolithiasis with a low complication rate. Both EHL‐POP and LL‐POP achieve similar efficacy in the endoscopic therapy of pancreatolithiasis. Further large randomized controlled trials are needed to compare EHL‐POP and LL‐POP with ESWL and evaluate whether POP may replace ESWL as the first‐line management of pancreatolithiasis.
The predictive value of PET/CT for distant recurrences in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy
Authors: Kong Joseph C , Ryan Jennifer , Akhurst Timothy , Ngan Samuel Y , Michael Michael , Tie Jeanne , Warrier Satish K , Heriot Alexander G 
Published: August 2021

AbstractIntroductionIt is well recognized that pathological complete response (pCR) for locally advanced rectal cancer after neoadjuvant chemoradiotherapy (CRT) confers a positive survival advantage. Despite this, a small proportion of patients can develop distant recurrence, and these are the patients that will likely benefit from adjuvant therapy. This study aims to investigate the role of PET/CT as a functional imaging to stratify patients according to their risk of distant recurrence.MethodsThis is a retrospective analysis of a prospectively maintained database in a single quaternary teaching hospital from 2010 to 2019. All consecutive cases of locally advanced rectal cancer with restaging PET/CT were included. The primary outcome measure was 5‐year OS and distant recurrence‐free survival.ResultsA pCR and complete metabolic response (CMR) were identified in 47 (18%) patients and 73 (27.4%) patients respectively. Of these, 26 patients had both pCR and CMR and these patients remained free of local and distant recurrence at their last censored date. Patients with both pCR and CMR achieved the highest 5‐year overall survival of 96.2%, followed by those with pCR and incomplete CMR (iCMR) of 85.7%, non‐pCR and CMR of 85.1% and non‐pCR and iCMR of 83.1%. Independent predictors for 5‐year distant recurrence‐free survival were pathological and PET metabolic response, nodal staging and lymphovascular invasion (LVI).ConclusionIn conclusion, a PET/CT has the potential to better stratify patients of their risk of distant metastasis. However, a larger validation cohort is required before these findings can be translated to clinical utility.
Simultaneous genotyping of snails and infecting trematode parasites using high‐throughput amplicon sequencing
Authors: Hammoud Cyril , Mulero Stephen , Van Bocxlaer Bert , Boissier Jérôme , Verschuren Dirk , Albrecht Christian , Huyse Tine 
Published: August 2021

AbstractSeveral methodological issues currently hamper the study of entire trematode communities within populations of their intermediate snail hosts. Here we develop a new workflow using high‐throughput amplicon sequencing to simultaneously genotype snail hosts and their infecting trematode parasites. We designed primers to amplify four snail and five trematode markers in a single multiplex PCR. While also applicable to other genera, we focused on medically and economically important snail genera within the superorder Hygrophila and targeted a broad taxonomic range of parasites within the class Trematoda. We tested the workflow using 417 Biomphalaria glabrata specimens experimentally infected with Schistosoma rodhaini, two strains of Schistosoma mansoni and combinations thereof. We evaluated the reliability of infection diagnostics, the robustness of the workflow, its specificity related to host and parasite identification, and the sensitivity to detect co‐infections, immature infections and changes of parasite biomass during the infection process. Finally, we investigated its applicability in wild‐caught snails of other genera naturally infected with a diverse range of trematodes. After stringent quality control the workflow allows the identification of snails to species level, and of trematodes to taxonomic levels ranging from family to strain. It is sensitive to detect immature infections and changes in parasite biomass described in previous experimental studies. Co‐infections were successfully identified, opening the possibility to examine parasite–parasite interactions such as interspecific competition. Together, these results demonstrate that our workflow provides a powerful tool to analyse the processes shaping trematode communities within natural snail populations.
Performance of methods to detect genetic variants from bisulphite sequencing data in a non‐model species
Authors: Lindner Melanie , Gawehns Fleur , te Molder Sebastiaan , Visser Marcel E. , van Oers Kees , Laine Veronika N. 
Published: August 2021

AbstractThe profiling of epigenetic marks like DNA methylation has become a central aspect of studies in evolution and ecology. Bisulphite sequencing is commonly used for assessing genome‐wide DNA methylation at single nucleotide resolution but these data can also provide information on genetic variants like single nucleotide polymorphisms (SNPs). However, bisulphite conversion causes unmethylated cytosines to appear as thymines, complicating the alignment and subsequent SNP calling. Several tools have been developed to overcome this challenge, but there is no independent evaluation of such tools for non‐model species, which often lack genomic references. Here, we used whole‐genome bisulphite sequencing (WGBS) data from four female great tits (Parus major) to evaluate the performance of seven tools for SNP calling from bisulphite sequencing data. We used SNPs from whole‐genome resequencing data of the same samples as baseline SNPs to assess common performance metrics like sensitivity, precision, and the number of true positive, false positive, and false negative SNPs for the full range of variant and genotype quality values. We found clear differences between the tools in either optimizing precision (Bis‐SNP), sensitivity (biscuit), or a compromise between both (all other tools). Overall, the choice of SNP caller strongly depends on which performance parameter should be maximized and whether ascertainment bias should be minimized to optimize downstream analysis, highlighting the need for studies that assess such differences.
Signs of life: Oxygen sensors confirm viability, measure oxygen consumption and provide rapid, effective contamination monitoring for field‐based tissue culture
Authors: Robinson Kelly J. , Armstrong Holly C. , Moss Simon E. W. , Oller Laura , Hall Ailsa J. , Bennett Kimberley A. 
Published: August 2021

Abstract

Understanding the ecology and evolution of wildlife and domesticated species requires knowledge of their physiological responses to environmental change and the constraints under which they operate. However, whole animal experiments are often limited in sample size and can be logistically and ethically challenging. Culture techniques represent a powerful approach, but are used infrequently in field research due to practical constraints. We used minimal tissue culture equipment in a remote field site for in vitro explant experiments using blubber from wild grey seals Halichoerus grypus. Assessing explant viability and detecting microbial contamination in remote field sites, where facilities are often small, unspecialised and more vulnerable to bacterial or fungal infection, present major challenges.

We investigated whether oxygen‐sensitive planar optodes (OSPO) in closed system respirometry could be used to assess oxygen consumption by blubber explants from suckling and fasting wild seal pups as a proxy for viability. We also explored whether OSPOs could provide rapid information on whole animal relevant physiological metrics by determining whether explant oxygen consumption correlated with the nutritional state of the animal, blubber depth and other tissue metabolic properties, including glucose uptake, lactate production and lipolysis.

Vials containing blubber explants consumed significant amounts of oxygen compared to controls, showing tissues were metabolically active. Oxygen consumption differed between nutritional states and blubber tissue depth. These differences were reflected in other tissue metabolic properties. Dissolved oxygen levels remained consistent over 24 hr in 94% of control vials containing only culture media. In 6% of control vials extremely rapid oxygen consumption preceded, by 2–3 days, colour changes in the phenol‐red containing media that indicate lactic acidosis from microbial metabolic activity.

Oxygen use in control vials was, therefore, an effective monitoring system that provided vital early warning of media contamination, allowing stocks to be discarded, which prevented erroneous results and avoided waste of valuable field time and irreplaceable samples. OSPO are thus a useful tool for simultaneously assessing tissue oxygen consumption, investigating functional physiological differences and monitoring microbiological contamination in culture experiments, particularly in field laboratories studying live tissues from wildlife.
A range‐wide monitoring programme for a critically endangered nomadic bird
Authors: Stojanovic Dejan , Rayner Laura , Tulloch Ayesha , Crates Ross , Webb Matthew , Ingwersen Dean , Runge Claire , Heinsohn Robert 
Published: August 2021

AbstractNomads challenge the prevailing approach to species conservation because their unpredictable resource‐driven movements hamper data collection. We developed a monitoring approach to address the conservation needs of critically endangered, nomadic regent honeyeaters Anthochaera phrygia, whose unpredictable movements occur at a continental scale. We used species distribution models that incorporated lagged effects of environmental variation on habitat suitability to refine and prioritise monitoring. By incorporating lagged effects of weather on occurrence, we identified a priority area within which we selected sites to survey. We undertook 1695 surveys in 2016 at 777 priority sites, and in 2017, we conducted a further 1434 surveys at 859 sites. We discovered nesting regent honeyeaters at new locations, locating 218 regent honeyeaters over two years. We validated performance of our priority mapping with the 2016–2017 survey results and the results of Crates et al. (J. Wildl. Manage. 2017, 81, 669). Predictive performance of the priority monitoring range map was best at estimated model values of approximately 0.7 and declined at both higher and lower values. Water availability was an important predictor, but poor resolution of the underlying data used in SDMs (e.g. temporary water sources) may explain our model performance. By accounting for spatiotemporal weather variation, we show that regional habitat suitability within the range of regent honeyeaters varied dramatically among years. Incorporating dynamic weather conditions is a useful approach to designing monitoring programmes for nomads. Our approach shows how to compromise between the need to account for the dynamic environmental conditions that drive site occupancy of nomads and the practical logistic constraints of implementing monitoring with scarce resources.
Space use and social interactions of Central African slender‐snouted crocodiles Mecistops leptorhynchus (Bennett, 1835) in Loango National Park, Gabon
Authors: Kouman Christine Y. , Ebome Angel E. A. , Ahizi Michel N. , Ouattara Mamadou , Ouattara Allassane , Fairet Emilie , Shirley Matthew H. 
Published: August 2021

AbstractMecistops leptorhynchus (Bennett, 1935) is among the least studied crocodylians worldwide, and little information exists on its movement patterns and habitat use. Using VHF radio tracking, we determined home range, core use areas and spatio‐temporal interactions for 30 individual M. leptorhynchus (14 females and 16 males), as well as providing a preliminary assessment of their habitat preferences and emergence dynamics in the Echira and Ngové Rivers, Loango National Park (Gabon). During two periods in 2010 (March to June–106 days, and October to November–49 days) we recorded 447 relocations of all tagged individuals (mean of 15 relocations/crocodile). Individual home range varied from 3.03 to 164.83 ha (median = 17.91 ha) and core use area from 0.25 to 25.37 ha (median = 1.50 ha). Males exhibited the largest home ranges whereas females recorded the largest core areas. Subadults covered the largest areas at both spatial scale. These difference were not statistically significant. Interestingly, M. leptorhynchus showed more space sharing than other crocodylian species, though with significant temporal avoidance—likely an adaptive behaviour used to reduce risks of conflict in high density environments. Our emergence assessment, though potentially confounded by transmitter placement, indicated limited basking behaviour in this species with unknown effect on its detection probability. All individuals, irrespective of size and sex, principally used main water courses. Ultimately our findings provide the first data on M. leptorhynchus home range and social organisation, which may help direct targeted management strategies for this species.
What we know about intra‐operative radiation exposure and hazards to operating theatre staff: A systematic review
Authors: Gogos Sophia , Touzell Amy , Lerner Lori Beth 
Published: August 2021

AbstractBackgroundThe widespread adoption of minimally invasive surgery and increased use of intra‐operative fluoroscopy places surgeons and trainees at risk of cumulative occupational radiation exposure. Unfortunately, there is limited published data specific to surgeons on the potential health implications. This study aims to review current literature regarding the hazards of cumulative radiation exposure among operating theatre staff.MethodsA systematic review was conducted of four databases for studies reporting on cumulative intra‐operative radiation exposure for operating theatre staff and the hazards associated with prolonged and frequent use. References from relevant studies were screened for additional texts. English language studies, controlled trials and cross‐sectional studies were included. Abstracts and full‐text studies were assessed for relevance and eligibility independently by two authors using Covidence.ResultsSix studies were included, with cancer being the most commonly reported long‐term health hazard possibly associated with cumulative radiation exposure. A 1.85 fold greater prevalence of all cancers and 2.9 fold greater prevalence of breast cancer was reported amongst female orthopaedic surgeons compared to a sex‐ and age‐adjusted population, but the results were not replicated amongst other surgical specialties. Multiple limitations of quantifying health risks of intra‐operative radiation exposure were identified, including identifying a dose‐effect relationship and confounders such as nulliparity and maternal age.ConclusionThis article highlights the lack of robust evidence regarding the potential hazards of cumulative occupational intra‐operative radiation exposure. This study demonstrates the importance of developing standardised national radiation safety protocols for surgical colleges and subspecialties to minimise risks to operating theatre staff.
Vertical transmission of methicillin‐resistant Staphylococcus aureus at delivery and its clinical impact: An observational, prospective cohort study
Authors: Ogura Jumpei , Inayama Yoshihide , Sasamoto Naoko , Hirayama Takahiro , Ohara Tsutomu , Sakai Mie , Suzuki Haruka , Yasumoto Koji , Suginami Koh , Yamanoi Koji 
Published: August 2021

AbstractIntroductionMethicillin‐resistant Staphylococcus aureus (MRSA) infection has a significant clinical impact on both pregnant women and neonates. The aim of this study was to assess accurately the vertical transmission rate of MRSA and its clinical impacts on both pregnant mothers and neonates.Material and methodsWe conducted a prospective observational cohort study of 898 pregnant women who were admitted to our department and 905 neonates from August 2016 to December 2017. MRSA was cultured from nasal and vaginal samples taken from the mothers at enrollment and from nasal and umbilical surface swabs taken from neonates at the time of delivery. We examined the vertical transmission rate of MRSA in mother‐neonate pairs. We used multivariable logistic regression to identify risk factors for maternal MRSA colonization and maternal/neonatal adverse outcomes associated with maternal MRSA colonization.ResultsThe prevalence of maternal MRSA colonization was 6.1% (55 of 898) at enrollment. The independent risk factors were multiparity and occupation (healthcare provider) (odds ratio [OR] 2.35, 95% confidence interval [CI] 1.25–4.42 and OR 2.58, 95% CI 1.39–4.79, respectively). The prevalence of neonatal MRSA colonization at birth was 12.7% (7 of 55 mother‐neonate pairs) in the maternal MRSA‐positive group, whereas it was only 0.12% (one of 843 pairs) in the maternal MRSA‐negative group (OR 121, 95% CI 14.6–1000). When maternal vaginal samples were MRSA‐positive, vertical transmission was observed in four of nine cases (44.4%) in this study. Skin and soft tissue infections developed more frequently in neonates in the maternal MRSA‐positive group than in the MRSA‐negative group (OR 7.47, 95% CI 2.50–22.3).ConclusionsThe prevalence of MRSA in pregnant women was approximately 6%. Vertical transmission caused by maternal vaginal MRSA colonization was observed in four of nine cases (44.4%). Although our study includes a limited number of maternal MRSA positive cases, the vertical transmission of MRSA may occur in up to 44% of neonates of mothers with vaginal MRSA colonization. Maternal MRSA colonization may be associated with increased development of skin and soft tissue infections in neonates via vertical transmission.