bluuebunny/crossref_metadata_2025_split huggingface dataset:
The contextual method of Academician Verbitsky: is a revolution in didactics possible?
Authors: Smirnov I. P. 
Published: April 2021

Introduction. The article provides an overview of the most notable pedagogical innovations (project method, programmed teaching, pedagogy of cooperation), mastered at the scientific level, but not widely used in educational practice. Special attention is paid to the paradigm of contextual education developed by the Academician of the Russian Academy of Education, Head of the Department of Social and Pedagogical Psychology in Sholokhov Moscow State University for the Humanities, A. A. Verbitsky and his scientific school. This paradigm accumulates many effective forms, methods and means, substantiated within the framework of various innovative approaches; however, it finds application only on the experimental sites of individual creative teachers of Russia.The aimof the present publication is to investigate the reasons for the rejection by educational practice to apply pedagogical innovations, conditions and prospects.Methodology and research methods. The author analyses the works of A. A. Verbitsky's scientific school, consistently developing the paradigm of contextual education in monographic and dissertation research, mastering it in the long-term teaching practice of the leading Russian university in the field of intelligent systems in humanities and applied humanities.Results and scientific novelty. The author rejects the widespread opinion about the inhibition of innovations by the conservative pedagogical environment and shows their ideological incompatibility between the centralised management of education and the autocracy of Russian society as a whole. It is proved that the imperative of the perception of pedagogical innovations by education is a change in the social environment.Practical significance. The author's assessments and conclusions create methodological prerequisites for developing a discussion about the mission of pedagogical science and the conditions for its development in modern Russian society. Thus, it could explain why the “didactocentrism”, proclaimed by John Amos Comenius, prevails in Russian education.
AVALIAÇÃO DO USO DE ANTIDEPRESSIVOS E ANSIOLÍTICOS POR ACADÊMICOS DO CURSO DE ENFERMAGEM
Authors: Coimbra Marla Brenda Pires , Araujo Renata Aparecida Faria de , Lemos Patricia de Lima , Ribeiro Lorena Araujo , Lisboa Helen Cristina Fávero 
Published: April 2021

Pesquisas evidenciam sintomas depressivos e de ansiedade entre acadêmicos de enfermagem, que mediante expectativas, desafios e incertezas ao longo do curso, ainda convivem com condições estressantes relacionadas ao paciente, sendo frequente nesse momento, o início do uso de psicofármacos. O estudo teve como objetivo avaliar o uso de antidepressivos e ansiolíticos por acadêmicos do curso de Enfermagem. Trata-se de estudo transversal, descritivo e analítico, que utilizou questionário contendo informações sociodemográficas, econômicas e sobre uso de antidepressivos e ansiolíticos. Realizou-se o teste de qui-quadrado de Pearson para verificar associação entre as variáveis utiliza antidepressivos/ansiolíticos e sociodemográficas/econômicas. Foram entrevistados 79 alunos e destes, 13 (16,4%) afirmaram fazer uso do medicamento. Em relação ao psicofármaco usado, os ansiolíticos foram os mais citados (52,63%), prevalecendo a prescrição por psiquiatra (46,15%), a maioria fazendo uso diário (92,31%), iniciado a medicação após ingresso na Universidade (61,54%) e nunca realizado alteração da dosagem sem consultar o médico (61,54%). Um percentual de 76,92% assegurou ter conhecimento sobre os efeitos adversos e declararam saber que a remoção do medicamento deve ser feita de maneira gradual (84,62%), no entanto 53,85% afirmaram ter interrompido o tratamento em algum momento sem consultar o médico. Na análise bivariada não houve associação entre as variáveis. Verificou-se a necessidade de ações voltadas para o acolhimento e escuta dos acadêmicos da área de enfermagem em relação aos transtornos depressivos e de ansiedade, e quanto ao uso racional e seguro dos psicofármacos, minimizando o sofrimento mental e as consequências do uso indevido dos fármacos.
Badania procesu żelowania zaczynów cementowych przeznaczonych do uszczelniania otworów przewiercających płytkie poziomy gazonośne
Authors:   Instytut Nafty i Gazu – Państwowy Instytut Badawczy, Rzepka Marcin , Kędzierski Miłosz ,   Instytut Nafty i Gazu – Państwowy Instytut Badawczy
Published: April 2021

The article presents issues related to the sealing slurry technology concerning gelling processes (i.e., static built-up of gel strength of cement slurries). Based on research conducted around the world, it can be concluded that the rate of gelling of the cement slurry has an important role in the process of preventing possible gas exhalations from the annular space. After the cement slurry is pumped into the borehole (especially in zones with shallow gas horizons), the so-called migration (exhalation) of the formation medium (i.e. uncontrolled outflow of e.g. gas from the annular space) may occur. The most important caused of gas migration from the shallow horizons after casings cementation are the inability to maintain a certain overpressure by the column of the binding cement slurry and too long binding of the cement slurry after pumping into the borehole. The initially liquid cement slurry, when pumped out of the casing, acts as a liquid, creating a certain hydrostatic pressure on the deposit. e.g. gas. However, after some time, the period of building the static gel strength (SGS) starts until the cement sets. The SGS building process, i.e. gelling of the cement slurry, reduces the ability to transmit hydrostatic pressure to the reservoir. The Oil and Gas Institute – National Research Institute has tested a number of cement slurry formulations characterized by different gelling and bonding times. Slurries were made on the basis of three typed of latex with the symbols L1, L2, L3, two types of water glass with symbols S1, S2, amorphous silica with the symbol CB, nano-components based on n-SiO2 and n-Al2O3 with the symbols NS and NA as well as high-molecular weight polymer with the symbol GS. Different amounts of setting accelerator were used with the tested slurries. Tests were carried out for eighteen cement recipes, which made it possible to select the optimal compositions of slurries with short gelling and setting times. The samples containing one of the types of latex in the appropriate concentration, the GS polymer, as well as those containing n-SiO2 and n-Al2O3, showed a very advantageous course of the gelation plot (static build-up of gel strength). Their TT transition times, reflecting the course of gelation, ranged from several to several tens of minutes (which is a proof of high ability to prevent gas migration from shallow gas accumulations). The cement slurries developed at the Oil and Gas Institute – National Research Institute, due to their good technological parameters, could be used in the process of cementing casing strings.
AULAS DE TROMPETE VIRTUAIS EM MEIO À PANDEMIA DA COVID-19 NO PROJETO ORQUESTRA JOVEM DO RIO GRANDE DO SUL: UM RELATO DE EXPERIÊNCIA
Authors: Soares Isac Costa 
Published: April 2021

Resumo: Trago neste texto, um relato de experiência relacionado às atividades e aulas de trompete que ocorreram durante a pandemia da Covid-19 no projeto Orquestra Jovem do Rio Grande do Sul[1] no período de 01 de março a 17 de dezembro de 2020. Abstract: I bring in this text, an experience report related to the activities and trumpet classes that occurred during the Covid-19 pandemic in the Youth Orchestra of Rio Grande do Sul project from March 1st to December 17th, 2020.
Automedicação de psicofármacos entre estudantes universitários de odontologia e medicina
Authors: Leite Lessa Araujo Aida Felisbela , Cristina Ribeiro Mara , Dias Vanderlei Aleska 
Published: April 2021

A vida acadêmica dos estudantes universitários exige dedicação e horas de estudos, de forma que muitos jovens para suportar o estresse e cansaço utilizam psicofármacos visando minimizar essas sensações. O objetivo desta pesquisa foi avaliar o uso de psicofármacos entre estudantes de medicina e odontologia. Trata-se de estudo descritivo, observacional, analítico e transversal, com 1.111 estudantes de duas instituições de ensino superior, regularmente matriculados nos cursos de medicina e odontologia, com idade igual ou superior a 18 anos. Foi aplicado um questionário estruturado com questões objetivas. As análises estatísticas foram realizadas no programa SPSS 22, e o nível de significância estabelecido como p < 0,05. O uso de psicofármacos ao longo da vida foi informado por 36,7%, enquanto 14,7% fez uso no último mês. A frequência de uso de psicofármacos é maior em situações de estresse, perda familiar ou submissão a cirurgias pelos estudantes. 37,2% afirmaram que obtiveram os medicamentos sem prescrição médica. As classes farmacológicas mais utilizadas foram ansiolíticos, antidepressivos e psicoestimulantes. Estes últimos foram mais consumidos por estudantes de medicina (p<0,05; OR: 2,12). Entre os fatores precipitantes para início do uso estão a demanda do curso (41,6%), outros fatores (33,7%) e problemas familiares (29,1%). 90,8% afirmaram ter consciência dos riscos quanto ao uso. O estudo verificou alta prevalência de uso não prescrito de psicofármacos entre os estudantes. Diante das necessidades encontradas, faz-se necessária a busca por estratégias de orientação e prevenção pelas universidades.
Jogo didático no ensino de conceitos lean na disciplina de administração de obras
Authors: Viana Marina Ribeiro , Santos Débora de Gois , Vasconcelos Carlos Alberto 
Published: April 2021

A mentalidade enxuta visa reduzir ou eliminar as atividades que não agregam valor ao produto através de melhorias contínuas e da redução de perdas. Trata-se de uma filosofia originada na década de 1990 e que, aos poucos, foi incorporada aos currículos dos cursos de Engenharia de Produção e Civil. Sob esse aspecto, por entender que a utilização de jogos didáticos pode ser eficiente, ao passo que estimula a participação e motiva os envolvidos, buscou-se investigar a utilização desse recurso pedagógico na difusão dos conceitos Lean entre futuros profissionais do setor. Diante do exposto, o presente trabalho originou-se de uma experiência com a aplicação do jogo Fábrica de Canetas em uma turma da graduação em Engenharia Civil. Para tal, foram realizadas simulações que permitiram abordar conceitos relativos à Produção Enxuta e ao gerenciamento da produção e, ao final, foi solicitado, aos integrantes dos grupos, a elaboração de um relatório sobre o que foi aprendido. Após a aplicação do jogo, foi possível observar maior participação dos discentes ao desenvolverem as atividades e ao comentar sobre os aspectos positivos e o que poderiam ser melhorados. Conclui-se, portanto, que os jogos podem auxiliar no ensino de teorias, sendo complementar ao que outrora fora visto em sala de aula.
Geographic variations in adherence to and persistence with adjuvant hormonal therapy for the privately insured women aged 18-64 with breast cancer in Texas
Authors: Kim Jung Hyun , Rajan Suja S. , Du Xianglin L. , Franzini Luisa , Giordano Sharon H. , Morgan Robert O. 
Published: April 2021

Abstract
Purpose: Objective of this study is to examine the geographical patterns of adjuvant hormonal therapy adherence and persistence and the associated factors in insured women aged 18-64 with early breast cancer in Texas. Methods: A retrospective cohort study was conducted by using claims data for population insured by Blue Cross Blue Shield of Texas (BCBSTX) from the year 2008 to 2013. Women diagnosed with early breast cancer who were taking tamoxifen or aromatase inhibitors (AIs) for adjuvant hormonal therapy with at least one prescription claim, from January 1, 2008 to December 31, 2012, and were enrolled through 2013, were identified. Adherence to adjuvant hormonal therapy and persistence on adjuvant hormonal therapy were calculated as outcome measures. Women without a gap between two consecutive dispensed prescriptions of at least 90 days in medication were considered as persistently taking the medications. Patient-level multivariate logistic regression models with repeated regional-level adjustments were used to determine the geographical variations and patient-level, provider-level, and area-level factors that were associated with adjuvant hormonal therapy adherence.Results: Of the 938 women in the cohort, 627 (66.8%) initiated adjuvant hormonal therapy. Most of the smaller HRRs have significantly higher or lower rates of treatment adherence and persistence rates relative to the median regions. The use of AHT varies substantially from one geographical area to another, especially for adherence, with an approximately two-fold difference between the lowest and highest areas and area-level factors were found to be significantly associated with the compliance of AHT. Conclusions: There are geographical variations in AHT adherence and persistence in Texas. Patient-level and area-level factors have significant associations explaining these patterns.
Developing an Energy Efficient Ubiquitous Agriculture Mobile Sensor Network Based Threshold Built-In Mac Routing Protocol (TBMP)
Authors: R Dhaya , R Kanthavel , A Ahilan 
Published: April 2021

Abstract
Smart agriculture has been a promising model with the intention of supervising farms by means of contemporary wireless technologies to enhance the quantity and quality of yield at the same time as minimizing the individual labor requirement. In addition the effective utilization of the Sensors as communication components that is the key one to monitor and manage soil, water, light, humidity, temperature. A Mobile Ad-hoc sensor node comprises sensors to gather real time environment from the agricultural land with the wireless communication technology and process the data before sharing information with other nodes in the network. On the other hand, the challenges have been enormously high path loss and lack of communication range under the environment when passing through soil, sand, water and other climatic conditions. As Wireless Sensor Networks (WSNs) has self-organized and adhoc wireless capability to monitor physical or environmental conditions, it can be used effectively in smart agriculture. As sensor nodes have been limited itself by means of power to be in active mode always, the design of such energy efficient Agriculture WSN is a paramount issue. Hence it has been planned to utilize the WSN as well as Ubiquitous technology for the smart agriculture with energy efficiency. With the purpose of build up a model, a Ubiquitous agriculture Mobile Sensor Network based Threshold built-in MAC Routing protocol (TBMP) has been proposed to make it fit for minimal resource utilization by comparing with the existing protocols IMR and PTSR. In addition, the testing will be done to monitor changes in environmental surroundings in the agricultural land smartly in order to obtain maximum usage of Ubiquitous concept by applying existing and proposed protocols.
Cannabidiol promotes neurogenesis in the dentate gyrus during an abstinence period in rats following chronic exposure to methamphetamine
Authors: Razavi Yasaman , Keyhanfar Fariborz , Haghparast Abbas , Shabani Ronak , Mehdizadeh Mehdi 
Published: April 2021

Abstract
Chronic methamphetamine (meth) abuse can lead to certain deficits in the hippocampal function by affecting the hippocampal neurogenesis and plasticity. To determine whether cannabidiol (CBD) can promote proliferation and maturation of neuronal progenitor cells, this study investigated the CBD effect on neurogenesis in the hippocampal dentate gyrus (DG) following chronic exposure to meth in rats. The rats received 2 mg/kg of meth twice a day for ten days. Next, immunofluorescence was performed to evaluate the effect of intracerebroventricular (ICV) administration of CBD (50 µg/5 µL) over an abstinence period (ten days) on the expression levels of neurogenesis markers, such as Ki67, NeuN, and doublecortin (DCX). Moreover, neuronal degeneration in the hippocampus was assessed using Nissl staining. According to our findings, repeated ICV administration of CBD improved cell proliferation and neurogenesis and increased the number of Ki-67 and DCX-positive cells in the abstinence period. Meanwhile, meth treatment subjects caused a significant decrease in the number of neurogenesis makers, as compared to the control group. The neurogenesis markers (Ki-67 and DCX) could be somewhat reversed, while NeuN did not show any significant increase in the CBD group. Our findings demonstrated that CBD can induce neuroprotective effects by modulating neurogenesis. Therefore, it can provide a promising therapeutic approach to improve cognitive performance following chronic exposure to psychostimulant drugs, including meth.
To Explore the Association Between Coagulation Function and Cerebral Microbleeds in Patients With Intracerebral Hemorrhage
Authors: Wang Zhenhua , Xiao Xinlan 
Published: April 2021

Abstract
Object:To verify the association between coagulation function and cerebral microbleeds(CMBs) in patients with intracerebral hemorrhage(ICH).Methods: A total of 193 patients underwent 3.0T magnetic resonance image(MRI) and were found ICH,they were divided into CMBs and non-CMBs groups. Indicators of coagulation function and some other flood and clinical data like prothrombin time (PT), activated partial thromboplastin time(APTT), international normalized ratio (INR) were enrolled.univariate and multivariate analysis were used to compare the difference between the two groups and screen risk factors. One or more receiver operating characteristic(ROC) curve were used to present the predictive value of the indicators for CMBs.Result: After a univariate analysis, the result showed that INR levels was significantly higher in the CMBs group than the non-CMBs group [1.06 (0.96, 1.12) vs. 0.97 (0.93, 1.03);P= 0.035), while there was no significant difference between PT, APTT, TT and FBI. To compare the baseline characteristic of the two groups showed that the age ,the proportion of a history of long-term antithrombotic treatment(AT), history of ischemic stroke(IS) and combination with a brain atrophy(BA) cases in the CMBs group was significantly higher than the non-CMBs group(each P < 0.05). Multivariate logistic regression analysis showed that age and IS were independent risk factors for CMBs in patients with ICH (OR:0.967, 95% CI: 0.936-0.998, P = 0.036; OR:2.016, 95% CI: 1.090-3.991,P = 0.044; respectively). ROC curves indicated that the area under curve(AUC) of age and IS for CMBs in patients with ICH was 0.610(95%CI:51.76%-70.32%) and 0.619(95%CI:53.32%-68.87%), respectively.Conclusion:Age and IS were the independent risk factor for CMBs in patients with ICH, among the coagulant indicators, INR showed a significantly higher level in the CMBs group than the non-CMBs group.
Degradation of Chitin using Chitinase Produced from Molecular Identified Bacteria
Authors: Aly Magda M , Seddiq Amna A , Baghdadi Afra M 
Published: April 2021

Abstract
Chitin and chitinolytic are beneficial enzymes for their biotechnological applications. Chitinases contribute to the generation of carbon and nitrogen in the ecosystem and can prohibit many fungal ailments that can threaten crop production worldwide. The goal of this work was the production and characterization of chitinase enzymes from bacteria isolated from the western region, Saudi Arabia for biocontrol fungal pathogens. Colloidal chitin from shrimp shells was prepared and used for isolation of chitinolytic bacteria on Mineral chitin agar medium from different sources. The most active isolates were AMM1which was characterized and identified as Alcaligenes aquatilis using 16SrRNA.. In conclusion, purified chitinase was success to produce from Alcaligenes aquatilis for medical uses and biocontrol process.
Optimal model of desalination planning under uncertainties in a water supply system
Authors: Wang Zongzhi , Ye Ailing , Liu Kelin , Tan Liting 
Published: April 2021

Abstract
A requirement for developing desalination in coastal regions suffering water scarcity is proposed to address the increased water demand and limited traditional water supply. The determination of plant capacity and water allocation scheme in a multiple-source water supply system, the first problem in planning desalination under stream flow and water demand uncertainties, remains a challenge. To address this gap, an interval-parameter two-stage stochastic programming model is developed in this study. The first-stage problem is to determine a proper desalination plant capacity, and the second is the water allocation scheme under uncertainties of natural stream flows, water demands, benefits and economic losses. The objective function is to maximize the net benefit of the system, and the cost function of desalination, including capital and operational costs, implying environmental impact, is linearized within a range of plant capacities to solve the model. The proposed approach is applied to an urban area of Weihai city in China to illustrate the validity of the model. The results suggest a capacity of 46 103 m3/d in 2030 and 56 103 m3/d in 2040. Sensitivity analyses of the parameters indicate that the unit price of electricity influences the utilization level of desalinated seawater, and a complementary relationship is observed between reclaimed water and desalinated seawater.
Constructing an Optimal Scar Tissue Mobilizer
Authors: Halverson Allie Claire 
Published: April 2021

Abstract
Background This project aimed to create a device optimal for mobilizing scar tissue. To do this, a Transcutaneous Electrical Nerve Stimulation (TENS) circuit and a rotating scar massage ball was constructed into one cohesive device. The TENS portion of the device aims to help relieve pain around the scar tissue, and the massager works to mobilize the scar tissue and relieve extra tension in the area. Mobilization of scar tissue can help patients who have undergone surgery or other physical trauma to attain proper skin function without pain and/or excessive tension. Results The rotating scar massage ball puts out 16 Newtons of centrifugal, rotating, force. This means that it is powerful enough to properly massage the area, but not too strong to the point where it would cause pain for the user. Conclusions This device utilizes two effective methods of pain relief and scar mobilization, making it optimal for the painless mobilization of scar tissue. It could be used by patients at home and by physical therapists in an office setting to help patients both mobilize their damaged, scarred tissue and relive pain around the affected area.