bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengembangan Media Teka-Teki Silang (TTS) untuk Pembelajaran Tematik Kelas VI SD
Authors: Darinah Darinah , Sukirno Sukirno 
Published: December 2021

Penelitian ini bertujuan untuk mengembangkan media pembelajaran TTS pada pembelajaran tematik di kelas VI SD. Penelitian ini merupakan Research and Development (R&D). Penelitian ini dilakukan di Gugus Untung Suropati, Sampel dalam penelitian ini dipilih secara cluster random sampling dari keseluruhan populasi adalah 11 kelas yang dijadikan kelas eksperimen dan kelas kontrol. Hasil penelitian menunjukkan bahwa: (1) Tahap penyusunan dan pengembangan media TTS ditempuh melalui 3 tahapan, yaitu menganalisis kebutuhan guru, menganalisis kebutuhan siswa, dan mengembangkan media TTS sebagai media pembelajaran tematik di kelas VI SD, (2) Validitas media TTS dinyatakan valid melalui penilaian dari hasil validasi ahli I dan II, saran dan masukan yang baik untuk dikembang-kannya produk media, serta respon pengguna media TTS. Dari hasil analisis validator diperoleh rata-rata presentase berturut-turut sebesar 78% dan 74,34%, dalam kategori sangat baik dan layak digunakan dalam kegiatan pembelajaran tematik kelas VI SD, dan (3) Tingkat keefektifan media TTS pada pembelajaran tematik dapat diketahui dari hasil uji coba produk yang menunjukkan bahwa hasil belajar pada kelas eksperimen yang menggunakan media TTS pada materi tema 9 pembelajaran tematik lebih baik daripada kelas kontrol yang menggunakan pembelajaran konvensional (buku teks). Media TTS juga mendapat respon baik oleh peserta didik.
Study of clinical features of patients with chronic eczema
Authors: Fomina L.V. , Dashchuk A.M. , Dobrzhanska E.I. 
Published: December 2021

Objective — s to study the clinical features of chronic eczema (CE) in 96 patients aged 18 to 78 years.
Materials and methods. The study was carried out in the city clinical dermatovenerological dispensary No. 5 in Kharkov. All patients gave written informed consent to participate in the study.The majority of them (66.7 %) were between 31 and 50 years old. The duration of dermatosis in 6.3 % of the surveyed persons ranged from 6 months to 1 year, in 33.3 % — from 1 year to 5 years, in 42.7 % — from 5 to 10 years, in 17.7 % — over 10 years. The most frequent causes of exacerbation in 51.1 % were neuropsychiatric trauma and stress, in 15.6 % — dise­ases of internal organs and acute respiratory diseases, in 13.5 % — contact with chemicals. In all patients, dermatosis was recurrent. Most often, the surveyed patients complained of moderate intensity itching (51 %) and severe sleep disturbances (66.7 %). Moderate leukocytosis and accelerated ESR were found in 21.9 % of patients, eosinophilia — in 5.1 %.
Results and discussion. 96 patients with chronic eczema aged 18 to 78 years were under observation. The diagnosis of chronic eczema was based on anamnestic data, patients’ complaints of itchy skin of varying intensity, objective examination of the patient, as well as recurrences of dermatosis for more than 1 year. The largest number of patients had dermatosis from 5 to 10 years. Chronic eczema in the observed patients was recurrent. The duration of remission was (4.9 ± 0.2) months. The duration of exacerbation was (6.1 ± 0.2) weeks. To characterize the severity of chronic eczema, a scoring system was used, according to which the average severity was (2.63 ± 0.08) points.According to the degree of skin lesions, the forms of dermatosis were limited and widespread. Patients complained of skin itching of varying intensity: more often itching of moderate intensity, periodic; painful, persistent, with an insurmountable need to scratch; short-term; no itching.Also, patients noted sleep disturbance in the form of difficulty falling asleep, sudden awakening at night and lack of a feeling of rest after waking up in the morning. 39 patients had bad habits (smoking, alcohol abuse).Сlinical analysis of blood revealed moderate leukocytosis, accelerated ESR, eosinophilia, signs of secondary infection.
Conclusions. The average age of the patients ranged from 31 to 50 years. All examined patients had recurrent dermatosis. The average degree of its severity was (2.63 ± 0.08) points. Most often, patients complained of moderate intensity itching (51 %) and severe sleep disturbances (66.7 %). In 21.9 % of the examined patients moderate leukocytosis and accelerated ESR were revealed, in 5.1 % — eosinophilia.
Molecule which changed the view on skin treatment
Authors: Fedorich L.Ya. 
Published: December 2021

Objective — to study the modern classification, mechanisms of action and clinical effects of vitamin A derivatives, to analyze retinoid for local treatment of various dermatoses with a universal mechanism of action at the epidermis and dermis levels.
Materials and methods. A review of the literature and an analysis of the results of international clinical trials of drugs based on the natural retinoid of the first generation — tretinoin (retinoic acid) is presented. The works of dozens of authors since 1980s to the present day are analyzed. Most sources provide detailed information on the results of topical retinoids in acne therapy, which are the base of clinical guidelines. Long-term (6 months or more) studies of retinoic acid-based preparations carried out in recent decades have discovered the unique clinical effects of tretinoin in the treatment of skin photoaging, actinic keratosis, etc. They are achieved due to the effect of tretinoid on the nuclear receptors of keratinocytes and fibroblasts.
Results and discussion. The molecular mechanisms of action of retinoic acid, realizing the cellular and tissue effects of the most studied retinoid, are systematized and grouped in a single review. It has been proven that a unique feature of tretinin is its ability to activate directly all subtypes of RARs- and, indirectly, RARs-nuclear receptors of skin cells. A new modern drug for external use is presented — AltrenoТМ lotion containing micronized 0.05 % tretinoin in combination with sodium hyaluronate, soluble collagen and glycerin. This combination exhibits the expected clinical efficacy in acne therapy and prevents side effects such as dryness, redness and exfoliation. AltrenoТМ is approved for use in children of 9 years of age and older.
Conclusions. Tretinoin (retinoic acid) is a modern powerful retinoid with a universal mechanism of action, recommended for the treatment of acne.
Calculation of the Shaping of a Space Umbrella Antenna During Strong Bending of Radial Rods Connected Along Parallels by Tensile Cables
Authors: Russkikh S. V. , Shklyarchuk F. N. 
Published: December 2021

Abstract—
A cyclically symmetric umbrella antenna is considered, the frame of which consists of flexible inextensible radial rods connected in nodes along parallels by tensile cables. In the initial transport position, the multilink rods are packed in packages oriented in the direction of the system axis. After the packing ties are removed, the rods are deployed in radial planes under the action of elastic springs connecting the links, and are fixed in rectilinear positions at a given angle with respect to the axis, at which all cables connecting the same type of rod nodes take the form of regular polygons, while remaining loose. Further, under the action of the force of a damping hydraulic cylinder with pre-compressed springs, the root parts of all rods are slowly turned to the stops. In the final position, the radial rods, connected at the nodes by tensioned cables, take a curved shape. The tensile stiffnesses of the cables are determined so that the radial and axial coordinates of the nodes of the curved rods coincide with the coordinates of the points of the given surface of revolution.
A model of strong bending of a flexible inextensible rod is constructed taking into account the unknown radial reactions of tensioned cables acting on it at the nodes. The links of the rod are considered as “cantilever” elements connected in series at the nodes in local coordinate systems, which can make large displacements and turns. The bending of each element is described by two specified functions, the shrinkage of the element due to bending is taken into account in a quadratic approximation. The obtained nonlinear deformation equations of the system, taking into account the geometric connections at the nodes, are solved by the method of successive approximations with respect to the unknown reactions of the cables. The obtained values of the reactions are then used to determine the required tensile stiffness of the cables at the given coordinates of the nodes.
As an example of the calculation, a parabolic antenna is considered for various numbers of radial rods and components of links. The estimates of the accuracy of the proposed computational model of the antenna shaping are carried out.
A Study of the ST Changes in the aVR Lead on 12-Lead ECG to Identify Infarct - Related Artery (IRA) in Patients With Acute Inferior Wall Myocardial Infarction
Authors: Mahaseth Aditya , Nepal Bikas , Karki Biplave , Ghimire Jeet , Pandey Naveen , Shah Prashant , Karki Prahlad 
Published: December 2021

BACKGROUND: Lead avR is a valuable but mostly ignored lead in clinical electrocardiography. Recently, ST-segment depression in lead aVR during an inferior wall myocardial infarction has been suggested as a predictor of LCX artery involvement.
METHODS: This study was a single centre cross sectional observational study done in BPKIHS, Dharan from February 2018 to January 2020. Patients presenting to the OPD or emergency room of BPKIHS diagnosed as acute inferior wall myocardial infarction based on clinical symptoms, ECG and/or Cardiac tropinin I levels, and planned for coronary angiography, meeting the inclusion and exclusion criterias were included.
RESULTS: Among 134 cases, male:female ratio was 1.3:1. Overall, 38 patients (28.4%) were found to have aVR depression and 96 patients (71.6%) were without aVR depression. The culprit artery was found to be the right coronary artery in 95 patients (70.9%), the LCx in 39 patients (29.1%). The sensitivity and specificity of ST-segment depression in lead aVR for LCx as the culprit artery were 92.3% and 97.9% respectively. Positive predictive and Negative predictive value for LCx as the culprit arteries were 94.74% and 96.87%. The sensitivity, specificity, positive predictive value and negative predictive value for RCA as the culprit artery were 97.89%, 92.3%, 96.89% and 94.73% respectively.
CONCLUSION: Significant ST depression in aVR is associated with a higher specificity and good sensitivity for LCX lesions, the ST changes in this lead should be carefully examined in all patients who are suspected of having inferior wall myocardial infarction.
Ultrasound fetal biometry in third trimester in urban Nepalese population
Authors: Kayastha Bhuwan , Giri Shahjan Raj , Gurung Bibek , Panta Om Biju 
Published: December 2021

INTRODUCTION: Fetal biometry is an important component of fetal growth surveillance and can detect small for gestation age fetuses. However, we use growth curves from studies done in other high-income countries and do not have a standard of our own. This study aims to study the deviation of biometry and expected fetal weight from these curves in pregnancy with normal birth weight term deliveries.
METHODS: The study was a retrospective hospital record-based study including term delivery from 2018 May to 2020 January. All lowrisk patients visiting ultrasound OPD in our hospital in 3rd trimester were retrieved and included in the study. Patient with low AFI, major fetal anomaly, abnormal fetal heart rate, preterm delivery, birth weight less than 2500 gm (low birth weight), intrauterine fetal demise, preeclampsia or other complications were excluded from the study. Fetal biometry and expected fetal weight were evaluated. Data was entered in predesigned performa and analysis was performed with IBM SPSS 20.0.
RESULTS: A total of 590 ultrasound examinations done in 372 patients were included in the study. Mean age of the patients was 30.78+/-3.98 years, median age was 30 years (IQ range-5). Approximately 316(53.6%) patients were under 30 years of age, 198(33.6%) patients were between 30-35 and 76(12.9%) patients were above 35 years. Median gestational age at birth was 39 weeks and median birth weight was 3120 grams. Median and percentile for various biometry was calculated. EFW was below 50th percentile in 424(71.9%) according to WHO chart. The median percentile for EFW was 30.6 (IQ-33.6).
CONCLUSION: Expected fetal weight in Nepalese population is smaller than that predicted by WHO chart. Development of country specific fetal growth curve is recommended for accurate fetal growth surveillance.
Laparoscopic cholecystectomy during COVID-19 pandemic- Retrospective analysis of tertiary care centre
Authors: Laudari Uttam , Pradhan Rosi , Shrestha Dibesh , Timilsina Bibek , Sapkota Suhail , Karki Dimindra , Lamichhane Suraj , Parajuli Anuj 
Published: December 2021

INTRODUCTION: Laparoscopic cholecystectomy is the most commonly performed general surgical procedure. During the COVID-19 pandemic, general recommendation worldwide is to postpone elective surgeries as far as possible to decrease the resource utilization and also aerosol-related transmission among hospital staff and patients. We conducted this study to see the burden of gallbladder disease, their management and outcomes of all patients who presented to our centre during first wave of COVID-19 pandemic.
METHODS: We conducted a retrospective analysis of all patients who underwent laparoscopic cholecystectomy at the Hospital for Advanced Medicine and Surgery (HAMS) after the commencement of strict lockdown in the first wave of the COVID-19 pandemic. Ethical approval for the study was taken from Nepal Health Research Council. All the surgeries were performed as per HAMS interim policy for infection prevention and control during the COVID-19 pandemic. Data were extracted from the discharge sheet and outcomes in terms of duration of hospitalization, morbidity, mortality, and COVID -19 infection among patient and operating team staff after surgery were assessed.
RESULTS: Out of 110 cases operated for gallbladder disease, 90 patients were included in the study with complete data. The most common presentations were dyspepsia (28) and biliary colic (22). Patients were managed with laparoscopic cholecystectomy (79), percutaneous cholecystostomy (4), laparoscopic subtotal cholecystectomy (5), open cholecystectomy (1). The median duration of hospitalization 22 hours. There was no COVID-19 transmission among staff and patients.
CONCLUSIONS: Laparoscopic cholecystectomies are feasible during COVID-19 pandemic and safely performed following infection prevention guidelines. It can be still be performed in day case basis to decrease the bed occupancy and avoiding crowd in hospitals.
DRYING WHITE CABBAGE ON A CONVECTIVE DRYING BENCH
Authors: Petrova Zh. , Paziuk V. , Vishnevsky P. , Grakov D. , Grakov О. 
Published: December 2021

Known methods of production of dried cabbage are long-term production processes that take place within 12… 24 hours. Therefore, it is necessary to develop new methods of drying and intensification of this process.
The article presents experimental studies of the kinetics of the drying process of white cabbage with different energy supply and their combinations, such as convective, infrared and convective-infrared drying methods. The main criterion for choosing a rational mode of drying is the quality of raw materials after heat treatment, in particular the visual assessment of color by temperature.
During convective drying, the analysis of temperature regimes for process intensity and quality of raw materials was performed. The drying mode of 60ºC which satisfies all requirements for quality of material was chosen. To speed up the process, it is proposed to reduce the drying time by introducing a step mode of 80 / 60ºC, which also reduces the energy component.
Infrared radiation intensifies the process due to the rapid heating of the material, but in turn it burns. Therefore, a combined convective-infrared method is proposed in which the temperature in the product did not exceed 60 ° C. This method of drying showed good results with a shorter drying time.Infrared radiation intensifies the process due to the rapid heating of the material, but in turn it burns. Therefore, a combined convective-infrared method is proposed in which the temperature in the product did not exceed 60 ° C. This method of drying showed good results with a shorter drying time.
HEAT TRANSFER IN GRADIENT LAMINAR FLOWS
Authors: Avramenko A.A. , Tyrinov A.O. , Dmitrenko N.P. , Kovetska Yu.Yu. 
Published: December 2021

The development of new areas of research in the field of theoretical thermophysics requires reliable analytical solutions that could take into account the main aspects of physical parameters in the studied objects. One such analytical technique is symmetry groups.
On the basis of symmetry groups the problem of heat transfer in gradient laminar flows is solved in the paper. For the first time, the symmetries of the energy equation for the boundary layer at an arbitrary changing velocity at marching direction are obtained. Examples of the use of group analysis methods for the study of heat transfer in the boundary layer of an incompressible fluid are demonstrated. The problems of heat transfer in the boundary layer on a heat-conducting wall with a constant temperature and on a heat-insulated wall are considered. Analytical relations for temperature and heat transfer coefficients distribution are obtained.
PROSPECTS OF BIOMETHANE PRODUCTION IN UKRAINE
Authors: Geletukha G.G. , Matveev Yu.B. 
Published: December 2021

Biogas upgrading to quality of natural gas (NG) creates possibility to supply biomethane to the NG grid, easy transportation and production of electricity and heat in locations where there is guaranteed consumption of thermal energy. Biomethane as a close NG analogue can be used for heat and electricity production, as soon as motor fuel and raw material for chemical industry.
The International Energy Agency (IEA) estimates that the world's annual biomethane production potential is 730 bcm (20% of current world's NG consumption). World biomethane production reached almost 5 bcm/yr in 2019. According to forecast of the European Biogas Association the biogas and biomethane sector may almost double its production by 2030. According to IEA estimates, annual world biomethane production could reach 200 bcm in 2040 in case the sustainable development strategy is implemented
Currently, the Bioenergy Association of Ukraine estimates the potential for biogas/biomethane production in Ukraine using fermentation technology as 7,8 bcm/yr (25% of the country's current NG consumption). The roadmap of bioenergy development in Ukraine until 2050 envisages growth of biomethane production to 1,7 bcm in 2035 and up to 3 bcm in 2050.
Currently the prospects for green hydrogen development are well known. The authors support the need of hydrogen technologies as one of the way for production and use of renewable gases. However, they believe that biomethane has no less prospects.
Transporting of one cubic meter of biomethane through gas pipeline at 60 bar pressure transmits almost four times more energy than transporting of one cubic meter of hydrogen. This is fundamental advantage of biomethane. Another advantage is the full readiness of gas infrastructure for biomethane. Given the cost of gas infrastructure modernization to use hydrogen, it is more cost-effective to convert green hydrogen to synthetic methane.
Currently, biomethane is in average three times cheaper than green hydrogen, the cost of the two renewable gases is expected to equalize by 2050, and only further possible reduction in the cost of green hydrogen below $2/kg will make green hydrogen cheaper than biomethane. Therefore, the greatest prospects can be seen in the combination of the advantages of both renewable gases and conversion of green hydrogen into synthetic methane (power-to-gas process).
Authors believe that after adoption of legislation to support the development of biomethane production and use in Ukraine, the bulk of biomethane produced in the country will be exported to EU, where more favourable conditions for biomethane consumption are developed. As Ukraine's economy grows, more and more of the biomethane produced will be used for domestic consumption.
PROBLEMS OF BIOMASS ASH UTILIZATION FROM BOILER HOUSES IN UKRAINE
Authors: Kramar V.G. 
Published: December 2021

As result of the study, it was estimated that in 2019 in Ukraine the annual biomass ash formation to be utilized, amounted to 132 thousand tons, and in the future, subject to the goals of bioenergy development, it may increase almost 10 times until 2050. The main way to treat biomass ash in Ukraine is to bury it in landfills, partly use in landfills as an insulating material, and partly as fertilizer, mainly in homesteads. In Ukraine, the widespread use of biomass ash is limited by the lack of legal requirements for its utilization, absence of technical requirements for its use in the construction industry, complex procedure of state registration of pesticides and agrochemicals, which puts biomass ash in unequal competitition with the mineral fertilizers. Also, a certain barrier to the use of biomass ash as a fertilizer is its physical and chemical characteristics, which require special methods of its application. The increase in useful utilization of ash requires field research of its effectiveness as a fertilizer, development of different types of fertilizers based on biomass ash for different types of soils and crops and methods of their use with proven efficiency, development of the most efficient utilization methods of the ash, which does not meet the requirements of its use in agriculture, in other industries.
Streptococcus mutans Antibacterial Activity of 0.1% Lysozyme Tooth Paste as an Alternative for Children Below 3 Years Old in Preventing Early Childhood Caries (ECC) (Experimental Laboratory Study)
Authors: Octiara Essie , Sutadi Heriandi , Siregar Yahwardiah , Primasari Ameta 
Published: December 2021

One of many possible ways of preventing Early Childhood Caries (ECC) is by removing tooth debris. Fluoride tooth paste usage by children under 3 years old must follow recommended quantity, because of its possibility of being ingested which then might cause fluorosis. Lysozyme as an active element in a toothpaste is able to mediate bacterial aggregation and inhibit bacterial adhesion and also activate bacterial autolysin by destructing bacterial cell wall. This study aimed to compared Streptococcus mutans antimicrobial activity of non-fluoride lysozyme toothpaste of various concentration such as 0.025, 0.05, 0.1, and 0.2 %. This was an experimental research with post test only design. The tested tooth paste was lysozyme-contained with 0.025, 0.05, 0.1 and 0.2% concentrations. Children tooth paste containing fluoride, enzyme tooth paste and 0.2% chlorhexidine became the positive control. Test of S. mutans antibacterial activity used 3 methods: disc diffusion, well, and microtiter plate method. Analytical test used Anova one way with Bonferoni post hoc and p<0.05 significant level. The results showed that all concentrations of lysozyme tooth paste had inhibitory effect on the growth of S. mutans (p<0.05). The highest mean of S. mutans antibacterial activity in lysozyme tooth paste were on 0.1 and 0.2% concentrations. Conclusion stated that 0.1% concentration of lysozyme tooth paste can be used as an alternative tooth paste for children under 3 years old