bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between chronic pain and psychosocial aspects in patients with haemophilic arthropathy. A cross‐sectional study
Authors: Ucero‐Lozano Roberto , López‐Pina José Antonio , Ortiz‐Pérez Alba , Cuesta‐Barriuso Rubén 
Published: December 2021

AbstractBackgroundPain is a major characteristic in haemophilic arthropathy. Identifying the psychosocial variables affected by pain can help when addressing these patients.AimTo assess the relationship between perceived intensity of chronic pain and joint damage, kinesiophobia, catastrophism, anxiety and perceived quality of life in adult patients with haemophilic arthropathy.MethodsMulticentre cross‐sectional descriptive study. Seventy‐seven adult patients with haemophilic arthropathy were recruited. The usual and maximum pain intensity (Visual Analog Scale), joint status (Haemophilia Joint Health Score), Kinesiophobia (Tampa Scale of Kinesiophobia), catastrophism (Pain catastrophizing scale), anxiety (State‐Trait Anxiety inventory) and perceived quality of life (36‐Item Short Form Health Survey) were evaluated. The correlation between usual and maximum pain intensity with quantitative variables was obtained with Spearman`s correlation test. Kruskal‐Wallis one‐way ANOVA analysed differences in perceived pain according to the severity and type of treatment, and development of inhibitors.ResultsThe usual intensity of perceived pain correlated positively with catastrophism, kinesiophobia, and state and trait anxiety. The same results were obtained when analysing the maximum perception of pain. We found an inverse correlation between the physical component of perceived quality of life and usual and maximum pain intensity perceived by patients.ConclusionPsychosocial factors affect the painful experience of patients with haemophilic arthropathy. Pain intensity affects the quality of life of these patients.
Deification as a Philosophical Problem: A Lutheran Reconstruction
Authors: Vainio Olli‐Pekka 
Published: December 2021

AbstractIn the most general terms, deification means participation in the divine nature, which starts the process where the believer is supposed to transform into the likeness of Christ. This article applies analytic tools to Lutheran theology in order to make sense of its central features. I aim to construct a model for the anthropology of deification which aims to function within these parameters to provide an account which satisfies the desiderata Lutheran theology has for the idea of deification and which does not commit itself to views that are obviously philosophically problematic. I offer arguments for a particular metaphysical construal of Luther’s idea of deification, while acknowledging that it leaves some questions unanswered. Finally, I make a suggestion for Lutherans as well as theologians from other traditions, to consider a metaphysical model developed by Peter van Inwagen as a possible parsimonious way of thinking about deification.
Gloriously Intertwined: A Bavinckian Account of the Single Organism of Dogmatics and Ethics
Authors: Xu Ximian 
Published: December 2021

AbstractRecent Bavinck studies show that Herman Bavinck (1854–1921) is not only a dogmatician but also an ethicist. This article seeks to demonstrate that, by intertwining dogmatics and ethics in a doxological way, that is, glorifying and exalting God in wonder and praise, Bavinck describes these two disciplines as inter‐independent yet intimately related; together they compose a single organism. Yet, Bavinck does not fully explicate the organic interconnection between dogmatics and ethics. Given this, I would like to take a step further to propose a Bavinckian analogical account of the two disciplines: ethics is embodied dogmatics, and dogmatics is ensouled ethics; together they constitute the organism of systematic theology. As such, dogmatics and ethics are understood to be two sub‐disciplines of systematic theology, which aims to promote flourishing life in light of God’s self‐revelation. Such a systematic theology serves to validate the due place of Christian theology in the academy.
A novel computer‐aided method for direct measurements and visualization of gingival margin changes
Authors: Kuralt Marko , Fidler Aleš 
Published: December 2021

AbstractAimTo introduce and validate a computer‐aided method for direct measurements and visualization of gingival margin (GM) changes.Materials and MethodsThe method consists of five main steps: digital model acquisition, superimposition, computer‐aided GM detection, distance calculation between the GM curves, and visualization. The precision of the method was evaluated with repeatability and reproducibility analysis (n = 78 teeth). The method's repeatability was evaluated by repeating the algorithm on the same digital models by two operators. The reproducibility was evaluated by repeating the algorithm on two consecutive digital models obtained with a scan−rescan process at the same time point on the same patient. For demonstration, the proposed method for direct measurements of GM changes was performed on patients who had undergone root coverage procedures and treatment of periodontal disease.ResultsExcellent repeatability was found for both intra‐ and inter‐operator variability, that is, 0.00 mm, regarding computer‐aided GM detection. The reproducibility of computer‐aided GM detection evaluated on scan−rescan models was 0.10 mm.ConclusionsThe presented method enables the evaluation of GM changes in a simple, precise, and comprehensive manner through non‐invasive acquisition and superimposition of digital models.
Use of the deep learning approach to measure alveolar bone level
Authors: Lee Chun‐Teh , Kabir Tanjida , Nelson Jiman , Sheng Sally , Meng Hsiu‐Wan , Van Dyke Thomas E. , Walji Muhammad F. , Jiang Xiaoqian , Shams Shayan 
Published: December 2021

AbstractAimThe goal was to use a deep convolutional neural network to measure the radiographic alveolar bone level to aid periodontal diagnosis.Materials and MethodsA deep learning (DL) model was developed by integrating three segmentation networks (bone area, tooth, cemento‐enamel junction) and image analysis to measure the radiographic bone level and assign radiographic bone loss (RBL) stages. The percentage of RBL was calculated to determine the stage of RBL for each tooth. A provisional periodontal diagnosis was assigned using the 2018 periodontitis classification. RBL percentage, staging, and presumptive diagnosis were compared with the measurements and diagnoses made by the independent examiners.ResultsThe average Dice Similarity Coefficient (DSC) for segmentation was over 0.91. There was no significant difference in the RBL percentage measurements determined by DL and examiners (). The area under the receiver operating characteristics curve of RBL stage assignment for stages I, II, and III was 0.89, 0.90, and 0.90, respectively. The accuracy of the case diagnosis was 0.85.ConclusionsThe proposed DL model provides reliable RBL measurements and image‐based periodontal diagnosis using periapical radiographic images. However, this model has to be further optimized and validated by a larger number of images to facilitate its application.
High serum iron markers are associated with periodontitis in post‐menopausal women: A population‐based study (NHANES III)
Authors: Costa Susilena Arouche , Ribeiro Cecilia Claudia Costa , Moreira Ana Regina Oliveira , Carvalho Souza Soraia de Fátima 
Published: December 2021

AbstractAimTo investigate the association between increased serum markers of iron (ferritin and transferrin saturation) and the severity and extent of periodontitis in post‐menopausal (PM) women.Materials and MethodsData from 982 PM women participating in NHANES III were analysed. Exposures were high ferritin (≥300 μg/ml) and transferrin saturation (≥45%). The primary outcome was moderate/severe periodontitis defined according to Centers for Disease Control and Prevention and the American Academy of Periodontology. The extent of periodontitis was also assessed as outcome: proportion of sites affected by clinical attachment loss ≥4 mm and probing depth ≥4 mm. Crude and adjusted prevalence ratio (PR) and mean ratio (MR) were estimated using Poisson regression.ResultsThe prevalence of moderate/severe periodontitis was 27.56%. High ferritin was associated with moderate/severe periodontitis in the crude (PR 1.55, p = .018) and in the final adjusted model (PR 1.53, p = .008). High ferritin and transferrin saturation levels were associated with a higher proportion of sites with clinical attachment loss ≥4 mm (p < .05).ConclusionsThe increasing serum iron markers seem to contribute to periodontitis severity and extent in PM women.
Ecology of planktonic ciliates in a changing world: Concepts, methods, and challenges
Authors: Weisse Thomas , Montagnes David J.S. 
Published: December 2021

AbstractPlankton ecologists ultimately focus on forecasting, both applied and environmental outcomes. We review how appreciating planktonic ciliates has become central to these predictions. We explore the 350‐year‐old canon on planktonic ciliates and examine its steady progression, which has been punctuated by conceptual insights and technological breakthroughs. By reflecting on this process, we offer suggestions as to where future leaps are needed, with an emphasis on predicting outcomes of global warming. We conclude that in terms of climate change research: (i) climatic hotspots (e.g. polar oceans) require attention; (ii) simply adding ciliate measurements to zooplankton/phytoplankton‐based sampling programs is inappropriate; (iii) elucidating the rare biosphere's functional ecology requires culture‐independent genetic methods; (iv) evaluating genetic adaptation (microevolution) and population composition shifts is required; (v) contrasting marine and freshwaters needs attention; (vi) mixotrophy needs attention; (vii) laboratory and field studies must couple automated measurements and molecular assessment of functional gene expression; (viii) ciliate trophic diversity requires appreciation; and (ix) marrying gene expression and function, coupled with climate change scenarios is needed. In short, continued academic efforts and financial support are essential to achieve the above; these will lead to understanding how ciliates will respond to climate change, providing tools for forecasting.
High‐pressure granulite facies re‐equilibration and zoisite–biotite dehydration melting during decompression of an ultrahigh‐pressure garnet clinopyroxenite from the island of Fjørtoft, Norway
Authors: Liu Penglei , Massonne Hans‐Joachim 
Published: December 2021

AbstractA garnet clinopyroxenite from the island of Fjørtoft, Western Gneiss Region (WGR) in Norway, has experienced a complex metamorphic evolution demonstrated by studies involving petrographic observations, mineral chemistry, phase equilibria modelling and geothermobarometry. This rock, originally an eclogite, documents ultrahigh‐pressure (UHP) conditions higher than 3.5 GPa (Stage 1), witnessed by Ca‐rich garnet inclusions in kyanite. The UHP assemblage was pervasively re‐equilibrated at high‐pressure (HP) granulite facies conditions around 1.75 GPa and 870°C, during which and/or somewhat before Ca‐poor garnet, sodian diopside, zoisite and biotite formed (Stage 2a). Dehydration melting of zoisite and biotite (Stage 2b) took place at similar pressure–temperature conditions. The produced melt was poor in Si and rich in alkalis and crystallized mainly to analcime + plagioclase + K‐feldspar. Oriented composite inclusions of quartz + amphibole + phengite ± garnet, found in clinopyroxene, are interpreted to have resulted from interaction between a fluid (hydrous melt and/or aqueous fluid) and clinopyroxene at the early retrogression Stage 3. Stage 1 resulted from deep subduction of the rock. Stage 2 followed after early exhumation probably due to stagnation at a hot and thickened orogenic root. Consequently, other HP granulite facies metabasites, which are similar to the studied garnet clinopyroxenite and widespread in the northwestern WGR, could have been transformed from former eclogite at this stage, too. In addition, this study provides a direct link between the generation of peralkaline melts and crustal anatexis in collision zones and new insights into the retrograde formation of oriented mineral inclusions in HP‐UHP minerals.
Readiness for hospital discharge in primary caregivers for children with acute lymphoblastic leukaemia
Authors: Lu Feng , Zhang Ge , Zhao Xiufang , Luo Biru 
Published: December 2021

AbstractAimTo investigate existing status and factors affecting the readiness for hospital discharge in primary caregivers for children with acute lymphoblastic leukaemia in China.BackgroundAcute lymphoblastic leukaemia is the most common childhood cancer, but there is not enough research on the readiness for hospital discharge.DesignA cross‐sectional study was performed by convenience sampling and questionnaire survey.MethodsA self‐developed questionnaire of general and clinical characteristics of patients, self‐developed questionnaire of general status of family and primary caregivers, questionnaire of readiness of hospital discharge scale and social support rating scale for primary caregivers were delivered to 264 primary caregivers of childhood acute lymphoblastic leukaemia patients. Data collection was carried out 24 h before discharge at bedside. In this study, the STROBE checklist was followed.ResultsIn total, 253 patients aged 0–16 years, including their primary caregivers in the hospital, were included from November 2016 to August 2017. Based on the readiness scale, the total mean score of readiness was 157.36. Based on the social support scale, the total mean score was 42.17. According to multivariate analysis, periods of chemotherapy (p < .001), complications (p = .019), family economic situation (p = .023), understanding of leukaemia (p < .001), objective support (p = .004), subjective support (p < .001) and availability of support (p = .045) were the main influencers of readiness.ConclusionsThe readiness for hospital discharge in primary caregivers for childhood lymphoblastic leukaemia patients is not satisfactory in China.Relevance to clinical practiceThis study has implications for public health administration, asking for better community services and disease education. In addition, more effort should be made to provide high‐quality family and primary caregiver assessments and discharge education by nurses.
Organizational Dischronization: On Meaning and Meaninglessness, Sensemaking and Nonsensemaking
Authors: Alvesson Mats , Jonsson Anna 
Published: December 2021

AbstractThis paper contributes to close up studies of how members in organizations experience and act in relationship to what is broadly and vaguely referred to as institutionalized structures and practices. Based on a case study about scorecards, a quality control system, it is illustrated that this practice works poorly, because of inconsistent ideas of purpose and functioning. We introduce the concept of organizational dischronization (OD) to illuminate this. OD indicates a deviation from the ideal of shared or synchronized meanings, and the existence of diverging understandings and lack of clarification of this, in an organization. The paper challenges some core ideas of institutional theory (logics) and sensemaking, suggesting the use of counter concepts such is organizational illogics and nonsensemaking, thus opening up for a broader and less ‘smooth’ understanding of how institutions and sensemaking work than assumed in the literature.
Design and pilot testing of therapeutic clothing for hospitalized children
Authors: Hawkins Beth , Ventresco Courtney , Cummings Meghan , McCaffrey Kimberly , Willwerth Andrew J. , Blume Elizabeth D. , VanderPluym Christina 
Published: December 2021

AbstractPurposeThe purpose of this paper is to describe the design and pilot program of a parent designed clothing option for hospitalized infants and children and to better understand the importance and effects of hospital clothing on families. Little research has been done on how clothing a hospitalized child impacts the child's quality of life and their parent's perception of care. Research has been limited to clothing in adults and its relation to infection.Design and MethodsA pediatric outfit (the Georgie) for hospitalized infants and children was designed based on insight from bedside nursing, physicians, parents, and supply chain personnel. The garment was pilot tested on select patients from intensive care units of a large children's hospital. A pre‐ and post‐use questionnaire was disseminated with questions focused on aspects of the child's care, comfort in changing child's clothes/diapers, number of times the Georgie was used and comfort level of using the Georgie. Survey responses were summarized using descriptive statistics.ResultsParents overall response to the Georgie was positive with great value placed on having their child dressed. All parents (n = 5) responded that too many lines were an obstacle to having their child dressed. Compared to the hospital Johnny, the Georgie (80%, n = 4) was the most preferred when placement and securement of monitoring lines was taken into consideration with one parent preferring a blanket and diaper only. Nurses felt the benefit outweighed the added effort in dressing the patient. The majority of the nurses had a positive initial reaction to the Georgie (80%, n = 4) and felt the lines or external devices were “very secure/secure” (80%, n = 4) when the patient was wearing the Georgie.Practice ImplicationsImplementing a new family centered care initiative of dressing critically ill patients in the Georgie may improve patient and family's quality of life while hospitalized. A larger scale study is indicated to assess the importance of dressing hospitalized pediatric patients for their families, to clarify the effect on nursing care, to optimize ability to stabilize lines, and to understand logistical issues.
Different priming effects of empathy on neural processing associated with firsthand pain and nonpain perception
Authors: Ren Qiaoyue , Yang Ye , Wo Ye , Lu Xuejing , Hu Li 
Published: December 2021

AbstractThe shared‐representation model of empathy is still debated. One of the major questions is whether empathy‐eliciting stimuli depicting others’ pain selectively activate the representations of self‐pain. To address this issue, we assessed the priming effects of empathy‐eliciting pictures on firsthand pain and nonpain perception, as well as its associated neural processing. In Experiment 1, when compared with nonpainful pictures depicting individuals’ body parts with no injury, participants primed by painful pictures showing individuals’ body parts with injury reported higher ratings for perceived intensity, unpleasantness, and salience of nociceptive and auditory stimuli, but they only exhibited increased N2 amplitude in response to nociceptive stimuli. In Experiment 2, the results from another group of participants replicated the observations of Experiment 1 and validated the findings in the non‐nociceptive somatosensory modality. Importantly, participants’ concern ratings for priming pictures predicted their unpleasantness ratings for subsequent nociceptive stimuli, while participants’ attention ratings predicted their unpleasantness ratings for subsequent auditory and tactile stimuli. This finding implies that empathy for pain might influence pain and nonpain perception via different psychological mechanisms. In summary, our findings highlight the existence of pain‐selective representations in empathy for pain and contribute to a better understanding of the shared‐representation model of empathy.
Palaeohistological inferences of resting metabolic rates inConcornisandIberomesornis(Enantiornithes, Ornithothoraces) from the Lower Cretaceous of Las Hoyas (Spain)
Authors: Cubo Jorge , Buscalioni Angela D. , Legendre Lucas J. , Bourdon Estelle , Sanz Jose L. , de Ricqlès Armand 
Published: December 2021

AbstractThe bone histology of non‐avian theropods such asTroodon, early pygostylians such asConfuciusornis, and neornithines, is characterized by the post‐hatching formation of fibrolamellar complex. In contrast, the cortex of enantiornithine birds, likeConcornisandIberomesornis, is made of poorly vascularized parallel‐fibred tissue. The cortex of metatarsals ofConcornis lacustrisMCCM‐LH21006 is composed of a thin layer of lamellar endosteal bone and a thick layer of almost avascular parallel‐fibred periosteal bone organized into an inner part containing large spherical osteocyte lacunae and a few secondary osteons, and an outer part containing flattened osteocyte lacunae and lines of arrested growth. The cortex of metatarsals ofIberomesornissp. MCCM‐LH09681 is similar to the inner layer described inConcornis. Endosteal bone, and the outer layer of periosteal bone containing flattened osteocytes and lines of arrested growth, are missing inIberomesornis, suggesting that this specimen is a sub‐adult. Here we test statistically a hypothesis suggesting that the absence of post‐hatching formation of fibrolamellar bone in Enantiornithes may be a side effect of their low resting metabolic rates (RMR). For this, we construct a palaeobiological inference model including osteocyte lacunar density (explaining a significant fraction of variation in RMR) and phylogenetic eigenvectors as predictor variables. RMR inferred forConcornisandIberomesornisare significantly higher than those measured in extant ectotherms, but they are not significantly different from the RMR measured in a sample of extant arboreal perching Neornithes of similar body size. We conclude that the ‘intermediate physiological condition’ hypothesis is rejected.
Anesthesia for pediatric rigid bronchoscopy and related airway surgery: Tips and tricks
Authors: Wang Jue T. , Peyton James , Hernandez Michael R. 
Published: December 2021

AbstractBronchoscopy‐guided diagnostic and interventional airway procedures are gaining in popularity and prominence in pediatric surgery. Many of these procedures have been used successfully in the adult population but have not been used in children due to a lack of appropriately sized instruments. Recent technological advances have led to the creation of instruments to enable many more diagnostic and therapeutic procedures to be done under bronchoscopic guidance. These procedures vary significantly in their length and invasiveness and require vastly different anesthetic plans that must be easily adapted to situational and procedural changes. In addition to close communication between the anesthesiology and procedural teams; an understanding of the type of procedure, anesthetic requirements, and potential patient risks is paramount to a successful anesthetic. This review will focus on new rigid bronchoscopic procedures, goals for their respective anesthetic management, and unique tips and trick for how to maintain adequate oxygenation and ventilation in each scenario.
Developmental respiratory physiology
Authors: Trachsel Daniel , Erb Thomas O. , Hammer Jürg , von Ungern‐Sternberg Britta S. 
Published: December 2021

AbstractVarious developmental aspects of respiratory physiology put infants and young children at an increased risk of respiratory failure, which is associated with a higher rate of critical incidents during anesthesia. The immaturity of control of breathing in infants is reflected by prolonged central apneas and periodic breathing, and an increased risk of apneas after anesthesia. The physiology of the pediatric upper and lower airways is characterized by a higher flow resistance and airway collapsibility. The increased chest wall compliance and reduced gas exchange surface of the lungs reduce the pulmonary oxygen reserve vis‐à‐vis a higher metabolic oxygen demand, which causes more rapid oxygen desaturation when ventilation is compromised. This review describes the various developmental aspects of respiratory physiology and summarizes anesthetic implications.