bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retrospective and prospective approaches of coronavirus publications in the last half-century: a Latent Dirichlet allocation analysis
Authors: Danesh Farshid , Dastani Meisam , Ghorbani Mohammad 
Published: March 2021

PurposeThe present article's primary purpose is the topic modeling of the global coronavirus publications in the last 50 years.Design/methodology/approachThe present study is applied research that has been conducted using text mining. The statistical population is the coronavirus publications that have been collected from the Web of Science Core Collection (1970–2020). The main keywords were extracted from the Medical Subject Heading browser to design the search strategy. Latent Dirichlet allocation and Python programming language were applied to analyze the data and implement the text mining algorithms of topic modeling.FindingsThe findings indicated that the SARS, science, protein, MERS, veterinary, cell, human, RNA, medicine and virology are the most important keywords in the global coronavirus publications. Also, eight important topics were identified in the global coronavirus publications by implementing the topic modeling algorithm. The highest number of publications were respectively on the following topics: “structure and proteomics,” “Cell signaling and immune response,” “clinical presentation and detection,” “Gene sequence and genomics,” “Diagnosis tests,” “vaccine and immune response and outbreak,” “Epidemiology and Transmission” and “gastrointestinal tissue.”Originality/valueThe originality of this article can be considered in three ways. First, text mining and Latent Dirichlet allocation were applied to analyzing coronavirus literature for the first time. Second, coronavirus is mentioned as a hot topic of research. Finally, in addition to the retrospective approaches to 50 years of data collection and analysis, the results can be exploited with prospective approaches to strategic planning and macro-policymaking.
A question of balance: study–work–life, perspectives from accounting students
Authors: Beatson Nicola J. , de Lange Paul , Oosthuizen Heinrich 
Published: March 2021

Purpose
Students have a finite amount of time that they can allocate between commitments of study–work–life. Striking a balance between these competing activities is an individual conundrum and this study aims to explore the impact of extramural activities and paid employment on the academic performance of accounting students.

Design/methodology/approach
Guided by Carroll’s model of school learning, the authors adopt a quantitative approach where they survey (N = 264) and gather responses (n = 195) from students with respect to their choices regarding spare time outside study. These perceptions are then compared to their academic performance. Quantitative responses were subsequently triangulated with interview findings to provide in-depth analysis.

Findings
Findings provide greater understanding for educators of the student lived experience, which reveals that the work, study and life balance is individually nuanced and is largely driven by the individual’s perceived level of interference from work, which is a significant predictor of academic performance.

Originality/value
Analysis of the determinants of student learning includes prior academic achievement, confidence with numbers, critical thinking, gender and prior accounting knowledge. Yet, little is known about the implication of activities outside the formal curriculum. This study addresses this void in the literature and provides a much-needed link back to accounting faculty’s pedagogical approaches as they adapt to a cohort’s learning behaviour. This study also adds to the debate on the need for more discussion with faculty to allow alternate arrangements based on extramural activities and employment commitments. Greater understanding of study–work–life balance for students provides an opportunity for new dialog between faculty and students.
Relative energy production determines effect of repowering on wildlife mortality at wind energy facilities
Authors: Huso Manuela , Conkling Tara , Dalthorp Daniel , Davis Melanie , Smith Heath , Fesnock Amy , Katzner Todd 
Published: March 2021

Abstract

Reduction in wildlife mortality is often cited as a potential advantage to repowering wind facilities, that is, replacing smaller, lower capacity, closely spaced turbines, with larger, higher capacity ones, more widely spaced. Wildlife mortality rates, however, are affected by more than just size and spacing of turbines, varying with turbine operation, seasonal and daily weather and habitat, all of which can confound our ability to accurately measure the effect of repowering on wildlife mortality rates.

We investigated the effect of repowering on wildlife mortality rates in a study conducted near Palm Springs, CA. We controlled for confounding effects of weather and habitat by measuring turbine‐caused wildlife mortality rates over a range of turbine sizes and spacing, all within the same time period, habitat and local weather conditions. We controlled for differences in turbine operation by standardizing mortality rate per unit energy produced.

We found that avian and bat mortality rate was constant per unit of energy produced, across all sizes and spacings of turbines.

Synthesis and applications. In the context of repowering a wind facility, our results suggest that the relative amount of energy produced, rather than simply the size, spacing or nameplate capacity of the replacement turbines, determines the relative rate of mortality prior to and after repowering. Consequently, in a given location, newer turbines would be expected to be less harmful to wildlife only if they produced less energy than the older models they replace. The implications are far‐reaching as 18% of US and 8% of world‐wide wind power capacity will likely be considered for repowering within ~5 years.
A new atypical short‐chain dehydrogenase is required for interfungal combat and conidiation in Trichoderma guizhouense
Authors: Zhu Hong , Zhang Jian , Gao Qi , Pang Guan , Sun Tingting , Li Rong , Yu Zhenzhong , Shen Qirong 
Published: March 2021

SummaryHypocrealean Trichoderma are the most extensively studied facultative mycoparasites against phytopathogenic fungi. Aerial hyphae of Trichoderma guizhouense can rapidly proliferate over Fusarium oxysporum hyphae, cause sporadic cell death and arrest the growth of the host. The results of the present study demonstrated that a unique short‐chain dehydrogenase/reductase (SDR), designated as TgSDR1, was expressed at a high level in T. guizhouense challenged by the hosts. Similar to other SDRs family members, the TgSDR1 protein contains a cofactor‐binding motif and a catalytic site. The subcellular localization assay revealed that the TgSDR1::GFP fusion protein translocated to lipid droplets in mycelia and conidia. The data obtained using reverse genetic approach indicated that TgSDR1 is associated with antifungal ability, plays an important role in providing reducing equivalents in the form of NADPH and regulates the amino sugar and nucleotide sugar metabolism in T. guizhouense upon encountering a host. Moreover, the TgSDR1 deletion mutant was defective in conidiation. Thus, TgSDR1 functions as a key metabolic enzyme in T. guizhouense to regulate mycotrophic interactions, defence against other fungi, such as F. oxysporum, and conidiation.
Validity and reproducibility of a semi‐quantitative food frequency questionnaire for Iranian adults
Authors: Mohammadifard Noushin , Haghighatdust Fahimeh , Kelishadi Roya , Bahonar Ahmad , Dianatkhah Minoo , Heidari Hossien , Maghroun Maryam , Dehghan Mahshid 
Published: March 2021

AbstractAimTo validate a semi‐quantitative food frequency questionnaire (SFFQ) and assess the dietary intake of Iranian adults.MethodsThis study was conducted among 113 healthy adults in Iran. We administered twelve 24‐hour dietary recalls (24DRs) during a year as a reference method. The 165‐item SFFQ was administered twice, along with the first and last 24DRs. To examine validity and reproducibility of SFFQ, the correlation coefficients (r) and de‐attenuated correlation coefficients and intra‐class correlation coefficient (ICC) between 24DRs and SFFQ were calculated. The Bland‐Altman method was used to assess agreement between the two methods.ResultsDe‐attenuated correlations varied from 0.42 (polyunsaturated fatty acids) to 0.62 (energy) (all P < .001) for nutrients and from 0.48 (oils and fats) to 0.65 (sweets) for food groups (all P < .05). We found reasonable reproducibility of SFFQ for both nutrients and food groups. ICC (95%CI) varied from 0.47 (0.15‐0.74) for saturated fatty acids to 0.64 (0.47‐0.76) for energy and from 0.43 (0.15‐0.62) for oils and fats to 0.58 for grains (0.31‐0.69). According to the Bland‐Altman plots, we observed an acceptable level of agreement between the two methods.ConclusionsWe found reasonable relative validity and acceptable reproducibility of SFFQ. This SFFQ can be used to classify individuals based on their dietary intake in our population.
Molecular characterization of chemosensory protein genes in Bactrocera minax (Diptera: Tephritidae)
Authors: Wang Zhao‐Xiang , Qi Zhen‐hua , Chen Jian , Wang Fu‐Lian , Gui Lian‐You , Zhang Guo‐Hui 
Published: March 2021

AbstractChemoreception is of great importance for survival of insects. Chemosensory proteins (CSPs) are believed to be involved in the perireceptor events of chemosensory system in many insect species, but this has not been clarified in the citrus fruit fly, Bactrocera minax, a serious dipteran pest of citrus crops. Previous studies indicated that four CSP genes were identified in many fly speices in Diptera. In the present study, we also identified four CSP genes in B. minax, namely BminCSP1–4, from a transcriptome database. All CSP proteins encoded by these genes bear the typical hallmarks of the CSP family: an N‐terminal signal peptide and the four highly conserved cysteine residues. Phylogenetic analysis comparing with other dipteran CSPs indicated that dipteran CSPs may evolved from three ancestral CSP genes, and revealed the sequence diversities of BminCSPs and showed that BminCSP1–4 are clustered in separate groups, indicating the possibility of their contrasting function in B. minax. Furthermore, the tissue distribution of the four CSP genes in adult B. minax was analyzed by real‐time quantitiative PCR. The results demonstrated that BminCSP3 are significantly transcriptionally enriched in antennae; BminCSP4 expressed primarily in heads; BminCSP1 and BminCSP2 showed high expressions in different tissues, such as antennae, abdomens and wings. Based on these findings, the different implications for the functions of BminCSPs are discussed. This study will offer a significant indication for further functional studies of the CSPs in B. minax.
Desflurane consumption with automated vapour control systems in two different anaesthesia machines. A randomized controlled study
Authors: Mostad Dagmar , Klepstad Pål , Follestad Turid , Pleym Hilde 
Published: March 2021

AbstractBackgroundIn general anaesthesia practice a fresh gas flow (FGF) of ≥0.5 L/min is usually applied. Automated gas delivery devices are developed to reduce volatile anaesthetic consumption by limiting gas flow. This study aimed to compare desflurane consumption between automated gas control devices compared to conventional low flow anaesthesia in the Flow‐I and Aisys anaesthesia machines, and to compare desflurane consumption between the two automated gas delivery devices. We hypothesised that desflurane consumption would be lower with automated gas delivery compared to conventional low flow anaesthesia, and that desflurane consumption could differ between the different gas delivery devices.MethodsWe allocated 160 patients undergoing robot‐assisted laparoscopic surgery into four groups, Flow‐I with automated gas control, Flow‐i with conventional low‐flow (1 L/min), Aisys with end tidal gas control and Aisys with conventional low flow. Patients were maintained at minimum alveolar concentration (MAC) 0.7‐0.8. Desflurane consumption was recorded after 9, 30 and 60 minutes of anaesthesia.ResultsAfter 60 minutes, compared to conventional low flow anaesthesia, automated gas delivery systems reduced desflurane consumption from 25.8 to 15.2 mL for the Aisys machine (P < .001) and from 22.1 to 16.8 mL for the Flow‐I (P < .001). Time to MAC 0.7 and stable FGF was shorter with Aisys endtidal control compared to Flow‐I automated gas control.ConclusionUnder clinical conditions, we found a reduction in desflurane consumption when using automated gas delivery devices compared to conventional low flow anaesthesia. Both devices were reliable in use.
17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex
Authors: Harrison David E. , Strong Randy , Reifsnyder Peter , Kumar Navasuja , Fernandez Elizabeth , Flurkey Kevin , Javors Martin A. , Lopez‐Cruzan Marisa , Macchiarini Francesca , Nelson James F. , Markewych Adrian , Bitto Alessandro , Sindler Amy L. , Cortopassi Gino , Kavanagh Kylie , Leng Lin , Bucala Richard , Rosenthal Nadia , Salmon Adam , Stearns Timothy M. , Bogue Molly , Miller Richard A. 
Published: March 2021

AbstractIn genetically heterogeneous mice produced by the CByB6F1 x C3D2F1 cross, the “non‐feminizing” estrogen, 17‐α‐estradiol (17aE2), extended median male lifespan by 19% (p < 0.0001, log‐rank test) and 11% (p = 0.007) when fed at 14.4 ppm starting at 16 and 20 months, respectively. 90th percentile lifespans were extended 7% (p = 0.004, Wang–Allison test) and 5% (p = 0.17). Body weights were reduced about 20% after starting the 17aE2 diets. Four other interventions were tested in males and females: nicotinamide riboside, candesartan cilexetil, geranylgeranylacetone, and MIF098. Despite some data suggesting that nicotinamide riboside would be effective, neither it nor the other three increased lifespans significantly at the doses tested. The 17aE2 results confirm and extend our original reports, with very similar results when started at 16 months compared with mice started at 10 months of age in a prior study. The consistently large lifespan benefit in males, even when treatment is started late in life, may provide information on sex‐specific aspects of aging.
Online Education in a Pandemic: Stress Test or Fortuitous Disruption?
Authors: Ronkowitz Kenneth , Ronkowitz Lynnette Condro 
Published: March 2021

AbstractThis study explores higher education and the ways in which the shutdown caused by the COVID‐19 pandemic have accelerated the evolution of online education. This movement from face‐to‐face (F2F) education to a virtual environment was forced and unplanned. It can be viewed as a stress test for digital teaching and learning in the higher education system. The study addresses course conversions and the progress of online education in response to the current crisis.
Stanford parameters stratify the risk of recurrence in gynecologic smooth muscle tumors of uncertain malignant potential
Authors: Travaglino Antonio , Raffone Antonio , Gencarelli Annarita , Caldarelli Carola , Granata Marcello , Santoro Angela , Zannoni Gian Franco , Mollo Antonio , Zullo Fulvio , Insabato Luigi 
Published: March 2021

AbstractSmooth muscle tumor of uncertain malignant potential (STUMP) is an ill‐defined category of neoplasms, which represent a diagnostic challenge. We aimed to assess whether the Stanford parameters, that is, high mitotic index (≥10/10HPF), significant atypia (moderate‐to‐severe), and coagulative tumor cell necrosis (CTCN), even when focal or ambiguous, may be used to stratify the risk of recurrence in gynecological smooth muscle tumor of uncertain malignant potential (STUMP). Electronic databases were searched from their inception to October 2019. All studies assessing the Stanford parameters in gynecological STUMP series were included. STUMPs were subdivided according to the presence of the three Stanford parameters: high mitotic index, significant atypia, and CTCN. A Kaplan–Meier survival analysis was performed for recurrence‐free survival; hazard ratio (HR) was calculated in each category. Fourteen studies with 219 STUMPs were included. In 15.5% of cases, none of the three Stanford parameters were present, with a recurrence risk of 5.9%; 2.7% of cases showed high mitotic index alone, with a recurrence risk of 0% (HR = not calculable); 43.8% of cases showed significant atypia alone, with a recurrence risk of 18.7% (HR = 3.3; p = 0.012); 26.5% of cases showed CTCN alone, with a recurrence risk of 17.2% (HR = 3.1; p = 0.029); and 11.4% of cases showed at least two Stanford parameters, with a recurrence risk of 32% (HR = 7.5; p = 0.003). Stanford parameters may stratify the risk of recurrence of STUMP. Significant atypia and CTCN, but not high mitotic index, may be stand‐alone risk factors for recurrence in STUMP. The presence of at least two Stanford parameters, even if equivocal (e.g., uncertain or focal CTCN, focal significant atypia, mitotic index around 10/10HPF), might still be enough to support a diagnosis of leiomyosarcoma. Further studies are necessary in this field.
Suicide prevention in Japan: Government and community measures, and high‐risk interventions
Authors: Okamura Kazuya , Ikeshita Katsumi , Kimoto Sohei , Makinodan Manabu , Kishimoto Toshifumi 
Published: March 2021

AbstractSuicide is one of the most critical issues worldwide. In Japan, more than 30 000 people died by suicide every year between 1998 and 2011, and the Japanese government, local governments, and various other agencies have been working on suicide prevention programs to reduce the suicide rate. While the number of suicides is still high (more than 20 000 per year), many specialists are striving to further reduce the number of suicides in Japan. The Japanese government has played a central role in suicide prevention through the enactment of several laws, and in recent years, suicide prevention has shifted from government to community‐specific measures. This review discusses the suicide prevention measures that have been taken so far: (1) policy strategies for suicide prevention by the Japanese government, (2) community suicide prevention, and (3) strategic studies for suicide prevention. Finally, as shown in the ACTION‐J study, we conclude that cooperation among related organizations in the community, not just one institution, is important for future suicide prevention, especially youth suicide prevention.
Zebrafish as a tractable model of human cardiovascular disease
Authors: Bowley George , Kugler Elizabeth , Wilkinson Rob , Lawrie Allan , van Eeden Freek , Chico Tim J. A. , Evans Paul C. , Noël Emily S. , Serbanovic‐Canic Jovana 
Published: March 2021

Mammalian models including non‐human primates, pigs and rodents have been used extensively to study the mechanisms of cardiovascular disease. However, there is an increasing desire for alternative model systems that provide excellent scientific value while replacing or reducing the use of mammals. Here, we review the use of zebrafish, Danio rerio, to study cardiovascular development and disease. The anatomy and physiology of zebrafish and mammalian cardiovascular systems are compared, and we describe the use of zebrafish models in studying the mechanisms of cardiac (e.g. congenital heart defects, cardiomyopathy, conduction disorders and regeneration) and vascular (endothelial dysfunction and atherosclerosis, lipid metabolism, vascular ageing, neurovascular physiology and stroke) pathologies. We also review the use of zebrafish for studying pharmacological responses to cardiovascular drugs and describe several features of zebrafish that make them a compelling model for in vivo screening of compounds for the treatment cardiovascular disease.LINKED ARTICLESThis article is part of a themed issue on Preclinical Models for Cardiovascular disease research (BJP 75th Anniversary). To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v179.5/issuetoc
Vertical bone augmentation utilizing a titanium‐reinforced PTFE mesh: A multi‐variate analysis of influencing factors
Authors: Urban Istvan A. , Saleh Muhammad H. A. , Ravidà Andrea , Forster Andras , Wang Hom‐Lay , Barath Zoltan 
Published: March 2021

AbstractObjectiveTo clinically evaluate the use of a titanium‐reinforced PTFE mesh for vertical bone augmentation (VBA) of deficient alveolar ridges.Materials and methodsThis case series documented consecutive patients treated for VBA with a newly developed PTFE mesh. VBA was performed in anterior and posterior, maxillary and mandibular arches using anorganic bovine bone combined with autogenous graft in a 1:1 ratio. Healing time from initial surgery to re‐opening was recorded. Baseline vertical deficiency, absolute bone gain (gross height gained), and relative gain (percentage of defect fill with respect to the baseline deficiency) were registered.ResultsFifty‐seven patients (65 defects) were included in the analysis. The mean baseline vertical deficiency was 5.5 ± 2.6 mm. The mean absolute bone gain was 5.2 ± 2.4 mm. A relative gain of 96.5 ± 13.9% was achieved. Overall, 89.2% of cases showed complete regeneration, which occurred in all sites with baseline deficiencies of <5 mm, in 95.6% of sites with 5–8 mm deficiencies, and in 89.4% of sites with >8 mm deficiencies. Each 1‐mm addition to the baseline height deficiency increased the likelihood of incomplete bone regeneration by 2.5 times. Defect location had a statistically significant but a limited clinical impact on the bone height gained (<0.5 mm). Complications were observed in three cases (3%).ConclusionsVertical bone augmentation with titanium‐reinforced PTFE mesh and a mixture of autologous bone and xenograft is a safe and predictable procedure. The extent of the baseline vertical deficiency influences the percentage of bone gained.
Meta‐analysis of landowner participation in voluntary incentive programs for provision of forest ecosystem services
Authors: Mitani Yohei , Lindhjem Henrik 
Published: March 2021

AbstractMany voluntary incentive programs for provision of forest ecosystem services (ES) have low participation rates, insufficient enrollment areas, and inefficient ecological outcomes. Understanding participation behavior in such programs has therefore become a crucial part of policy success. We synthesized a large body of literature on the behavior of nonindustrial private forest owners based on surveys of stated (intended) participation or data on actual participation in existing or hypothetical programs. Using metaregression analysis, we examined how methodological, program‐characteristic, and economic‐incentive variables affected participation rate estimates. Participation rates tended to be overestimated when landowner participation was elicited in hypothetical choice situations (compared with real situations) and when dichotomous choice surveys (compared with census data) were used. The marginal effect sizes were quite large, for example, a 31% increase with use of stated choices in hypothetical scenarios, and practitioners should therefore be aware of them. However, use of choice experiment surveys in a modified scenario based on existing programs had no effect on participation when all other determinants were controlled for. Participation rates decreased significantly as length of the contract increased and when there was no withdrawal option. These results suggest that perpetual contracts have a lower negative impact on participation than time‐limited contracts with a duration of over 50 years. We confirmed that as compensation amounts increased, participation increased. One‐time up‐front payments were more effective in increasing initial participation than annual payments for contracts of over 5 years. We identified the robust determinants and the effect sizes of those determinants on landowner participation rate estimates, thereby contributing to a better understanding of forest owner behavior and offering useful insights to enable researchers and resource managers to improve the design and efficiency of new and existing forest ES programs.