bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE LEGAL ENTITY OF BAITUL MAAL WAT TAMWIL (BMT) AS A MICRO FINANCIAL INSTITUTION IN INDONESIA
Authors: Rijal Moh Syaifur 
Published: August 2021

The purpose of this study is to analyze the legal status and accountability of Baitul Maal Wat Tamwil (BMT) as a financial institution in Indonesia, because so far BMT has two main functions, the first, Baitul Maal as a non-profit institution that distributes zakat, infaq and alms, and the second, Baitul Tamwil is an institution whose function is to collect and to distribute commercial funds. This research uses normative research using a statutory approach and a conceptual approach. The results of this study indicate that the legal status of BMTs so far can only be established with the status of a cooperative or limited liability company. It refers to the characteristics possessed by BMT itself. The form of BMT accountability follows the form of liability that exists in the form of a BMT legal entity, if the loss is caused by the management or organs, the management or organs are jointly and severally responsible, but otherwise if the management or organs can prove then the management or organs are not jointly responsible for the losses incurred by BMT.
AN ANALYSIS OF INDEPENDENT CHARACTER OF PRIMARY SCHOOL STUDENTS IN LEARNING FROM HOME DURING THE COVID-19 PANDEMIC (A Case Study at SD Muhammadiyah 8 Surabaya)
Authors: Haiq Umar , Martati Badruli , Setiawan Fajar 
Published: August 2021

This research aims to determine the process of the development of the independent character of elementary school students in learning from home during the Covid-19 pandemic at SD Muhammadiyah 8 Surabaya in grades 4, 5, and 6 by referring to the achievement of indicators of independent character values and the obstacles that arise in their achievement. By using a qualitative approach, the discussion will be presented in a descriptive explanation. The research subjects are 99 upper-class student respondents (4, 5, and 6) at SD Muhammadiyah 8 Surabaya. The research is carried out only by taking data on March, April, and May 2020 as the research scope. In this research, data are collected giving online questionnaire observation techniques to students, accompanied by parents, and having direct interviews with class teachers and subject teachers. The discussion in this research shows that the level of development of the independent character of students has been built with an average of being in the category of culture and development even though there are still obstacles because they require assistance, either directly or indirectly from parents and teachers.Keywords: Character, Independence, Covid-19 Pandemic
Association Between Cardiac Enzyme Elevation and Clinical Prognosis of Neurosurgical and Neurocritically Ill Patients
Authors: Lee Jung Hwa , Lee Yun Im , Ahn Joonghyun , Ryu Jeong-Am 
Published: August 2021

Abstract
To investigate whether cardiac troponin (cTn) elevation is associated with in-hospital mortality and major adverse cardiac events (MACEs) in neurosurgical and neurocritically ill patients. Among neurosurgical patients admitted to the intensive care unit (ICU) from January 2013 to December 2019, those whose serum cTnI levels were obtained within 7 days after ICU admission were included. Propensity score matching was used. Each patient with cTnI elevation was matched to one of control patients. The primary endpoint was in-hospital mortality and the secondary outcome was MACE. cTnI elevation was shown in 702 (11.7%) of 6,004 patients. After propensity score matching, 617 pairs of data were generated by 1:1 individual matching without replacement. In multivariable analysis of overall and propensity score-matched population, cTnI elevation were associated with in-hospital mortality (adjusted odds ratio [OR]: 2.78, 95% confidence interval [CI]: 1.95 – 3.95 and adjusted OR: 1.77, 95% CI: 1.20 – 2.62, respectively). In addition, cTnI elevation were associated with MACE (adjusted OR: 3.75, 95% CI: 2.43 – 5.78 and adjusted OR: 4.04, 95% CI: 2.24 – 7.29, respectively). In this study, cTnI elevation was associated with in-hospital mortality and MACEs in neurosurgical and neurocritically ill patients.
Association Between Cardiac Enzyme Elevation and Clinical Prognosis of Neurosurgical and Neurocritically Ill Patients
Authors: Lee Jung Hwa , Lee Yun Im , Ahn Joonghyun , Ryu Jeong-Am 
Published: August 2021

Abstract
Background: To investigate whether cardiac troponin (cTn) elevation is associated with in-hospital mortality and major adverse cardiac events (MACEs) in neurosurgical and neurocritically ill patients. Methods: Among neurosurgical patients admitted to the intensive care unit (ICU) in a tertiary hospital from January 2013 to December 2019, those whose serum cTnI levels were obtained within 7 days after ICU admission were included. Propensity score matching was used. Each patient with cTnI elevation was matched to one of control patients. The primary endpoint was in-hospital mortality and the secondary outcome was MACE. Results: cTnI elevation was shown in 702 (11.7%) of 6,004 patients. After propensity score matching, 617 pairs of data were generated by 1:1 individual matching without replacement. Rates of in-hospital mortality in the overall population and the propensity score-matched population were higher for patients with cTnI elevation than for those without cTnI elevation (p < 0.001 and p = 0.003, respectively). In addition, MACEs were more common in patients with cTnI elevation than in those without cTnI elevation in the overall population and the propensity score-matched population (both p < 0.001). In multivariable analysis of overall and propensity score-matched population, cTnI elevation were associated with in-hospital mortality (adjusted odds ratio [OR]: 2.78, 95% confidence interval [CI]: 1.95 – 3.95 and adjusted OR: 1.77, 95% CI: 1.20 – 2.62, respectively). In addition, cTnI elevation were associated with MACE (adjusted OR: 3.75, 95% CI: 2.43 – 5.78 and adjusted OR: 4.04, 95% CI: 2.24 – 7.29, respectively). In survival analysis, the mortality rate of patients with cTnI elevation was significantly higher than in those without cTnI elevation for the propensity score-matched population (28.8% vs. 19.3%, log-rank test, p < 0.001).Conclusions: In this study, cTnI elevation was associated with in-hospital mortality and MACEs in neurosurgical and neurocritically ill patients.
The Seasonal Evolution of Subglacial Drainage Pathways Beneath a Soft-bedded Glacier
Authors: Hart Jane K. , Young David S. , Baurley Nathaniel R. , Robson Benjamin A. , Martinez Kirk 
Published: August 2021

Abstract
Subglacial hydrology is a key element in glacier response to climate change, but investigations of this environment are logistically difficult. Most models are based on summer data from glaciers resting on rigid bedrocks. However a significant number of glaciers rest on soft (unconsolidated sedimentary) beds. Here we present a unique multi-year instrumented record of the development of seasonal subglacial behavior associated with an Icelandic temperate glacier resting on a deformable sediment layer. We observe a distinct annual pattern in the subglacial hydrology based on self-organizing anastomosing braided channels. Water is stored within the subglacial system itself (till, braided system and ‘ponds’), allowing the rapid access of water to enable glacier speed-up events to occur throughout the year, particularly in winter.
Effects of Maternal Cannabis Use on the Newborn at Delivery and the Perinatal Period
Authors: Edet Angela , Cheng Philip Y. , Bhattacharyya Mouchumi , Kozik Teri M. 
Published: August 2021

Abstract
Background To evaluate if Activity Pulse Grimace Appearance Respiration (APGAR) scores and birthweight at delivery are different amongst newborns exposed to cannabis in utero compared to those who were not exposed to cannabis in utero. Also the rate of perinatal complications to the newborn was also examined. Methods This is a retrospective cohort study utilizing patient’s electronic health records that gave birth at a community hospital in the central valley of California in 2019. Exposure was defined as cannabis detected on universal urine toxicology testing completed on admission to hospital prior to birth/delivery. This was compared with urine toxicology testing that was negative for cannabis exposure. Results No significant difference between mothers who use cannabis and mothers who do not use cannabis during pregnancy in terms of the newborn’s one minute or five minute APGAR score. A significant difference between mothers who use cannabis compared to mothers who did not was found, in terms of the newborn’s birthweight. The rate of perinatal complications to the newborn was negligible at delivery and in the immediate perinatal period in our particular study. Conclusion To guide interventions in women of child bearing age in regards to illicit drug use in pregnancy particularly cannabis utilization. The medical knowledge of cannabis use in pregnancy is growing steadily and through continued further research; the body of knowledge can continue to grow in regards to outcomes in the newborn and the growing child.
Occurrence and characterisation of naphthenic acid fraction components in oil residues stranded on the shoreline of Chedabucto Bay, Nova Scotia, Canada
Authors: Yang Zeyu , Zhang Gong , Yang Chun , Shah Keval , Hollebone Bruce , Laforest Sonia , Lambert Patrick , Brown Carl 
Published: August 2021

Abstract
Purpose

This study aimed to investigate the occurrence, fate, and behaviour of oil components 46 years post-spill by analysing polar naphthenic acid fraction components (NAFCs).
Methods

Oil residues and sediment samples were collected from the shoreline of Chedabucto Bay, Nova Scotia, Canada, at sites affected by the 1970 Arrow oil spill, in June 2016. Sediments were extracted with Soxhlet extraction; NAFCs were separated through a silica gel column firstly, then analysed by high-performance liquid chromatography–high-resolution mass spectrometry (HPLC-HRMS).
Results and discussion

In all samples, the most abundant NAFC species were those having only oxygen as the heteroatom (Oo species, o indicating the number of oxygen atoms, from 1 to 8) and a high degree of saturation. O2 species accounted for 50–70% of all Oo species. NAFCs with sulphur heteroatoms were the second abundant species, then by those containing both nitrogen and oxygen heteroatoms. NAFCs in most Arrow oil residues had higher levels of oxygen species, especially for heavier molecular weight congeners, than the oil remaining stored in the sunken tanker. Environmental sediment samples, collected from near a marina away from the spill site, mainly contained a biological contribution with obviously recent petroleum oil input, whereas all Arrow oil residues were composed mainly of NAFCs that are characteristic of petroleum, and varied abundance between sites.
Conclusions

Characteristics of NAFCs from different sources varied from each other. Site-specific environmental conditions played a major role in controlling the fate and behaviour of oil components, including NAFCs.
Oxidative Medicine and Cellular Longevity Hsa_circ_0013731 mediated by E2F1 inhibits ferroptosis in hepatocellular carcinoma cells by sponging miR-877-3p and targeting SLC7A11
Authors: Fang Shiji , Chen Weiqian , Ding Jiayi , Zhang Dengke , Zheng Liyun , Song Jingjing , Tu Jianfei , Zhao Zhongwei , Qiu Rongfang , Weng Qiaoyou , Lu Chenying , Yang Yang , Ji Jiansong 
Published: August 2021

Abstract
Background: The regulatory loop between circular RNAs and microRNAs has a vital role in cell death. Ferroptosis is the form of iron-dependent cell death, which is distinct from necroptosis and apoptosis. Increasing evidences showed that ferroptosis is an important form of cell death in hepatocellular carcinoma.Methods: Real-time PCR were used to examine the expression level of circ_0013731 in hepatocellular carcinoma tissues. Edu and colony formation were performed to detect the cell proliferation. A luciferase reporter assay was used to determine the relationship between circ_0013731, miR-877-3p and SLC7A11. ChIP-qPCR assays were performed to examine the potential binding of E2F1 to the circ_0013731 promoter. Iron Assay Kit (Sigma Aldrich) was used to detect total iron or Fe2+. C11 BODIPY 581/591 staining and flow cytometer were used to examine the Lipid ROS. The role of circ_0013731 was examined in xenograft tumors model. Results: We revealed that the expression level of circ_0013731 was elevated in hepatocellular carcinoma. Moreover, E2F1 promote the transcription of circ_0013731. Overexpression of circ_0013731 promoted cell growth and inhibited ferroptosis in SMMC-7721 and QGY-7703 in vitro. miR-877-3p was proved as the direct target of circ_0013731. Then, inhibition of miR-877-3p enhanced cell growth and inhibited ferroptosis. Further mechanism research demonstrated that circ_0013731 upregulated the expression level of SLC7A11 by sponging miR-877-3p. Finally, circ_0013731 promoted HCC growth via miR-877-3p/ SLC7A11 axis in vivo.Conclusions: Our data reveal that circ_0013731 mediated by E2F1 facilitates cell growth and suppressed the ferroptosis via miR-877-3p/ SLC7A11 axis in hepatocellular carcinoma. Therefore, circ_0013731 could be acted as potential therapeutical target for hepatocellular carcinoma.
Comparison of Double-Lumen Tube and EZ-Blocker for Lung Separation in Thoracic Surgery - A Randomised Controlled Clinical Trial
Authors: Risse Joachim , Szeder Karsten , Schubert Ann-Kristin , Wiesmann Thomas , Dinges Hanns-Christian , Feldmann Carsten , Wulf Hinnerk , Meggiolaro Karl Matteo 
Published: August 2021

Abstract
Background:Double lumen tube (DLT) intubation is the most commonly used technique for lung separation. Bronchial blockers (BB) are an alternative, especially for difficult airways. The EZ-bronchial blocker (EZB) is the newest device of the BB family. Methods:A randomised, controlled trial was conducted in 80 patients undergoing elective thoracic surgery using DLT or SLT plus EZB for lung separation (German Clinical Trial Register DRKS00014816). The objective of the study was to compare the clinical performance of EZB with DLT. Primary endpoint was total time to successful lung separation. Secondary endpoints were time subsections, quality of lung collapse, difficulty of intubation, any complications during the procedure, incidence of objective trauma of the oropharynx and supraglottic space and intubation-related subjective symptoms.Results:74 patients were included, DLT group (n = 38), EZB group (n = 36). Median total time for lung separation [IQR] in DLT group was 234 seconds [207 to 294] versus 298 seconds [243 to 369] in EZB group (P=0.007). Quality of lung collapse was equal in both groups, DLT group 89.5% were excellent vs. 83.3 % in the EZB group (P=0.444). Inadequate lung collapse in five patients of the EZB group resulted in unsuccessful repositioning attempts and secondary DLT placement. Endoscopic examinations revealed significantly more carina trauma (P=0.047) and subglottic haemorrhage (P=0.047) in the DLT group. Additionally, postoperative subjective symptoms (sore throat, hoarseness) were more common in the DLT group, as were speech problems.Conclusions:Using the EZB results in prolonged lung separation compared to DLT, prima facie with equal quality of lung collapse for the thoracic surgeon. Five crossover cases demonstrated the superiority of the use of left-sided DLT especially in the indication for EZB for a right open thoracotomy or right video-assisted thoracoscopic surgery (VATS). Using the EZB showed only little evidence for reducing objective airway trauma e.g. less carina trauma as well as subjective complaints.Trial registration:German Clinical Trial Register DRKS00014816, prospectively registered on 07.06.2018https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00014816
Resistance Traits and Molecular Characterization of Multidrug-resistant Acinetobacter baumannii Isolates from an Intensive Care Unit of a Tertiary Hospital in Guangdong, Southern China
Authors: Chen Zhuo-Ran , Guo Hui-Wu , Pan Qing , Fu Mao-Zhang , Qiu Ying-Kui , Liu Jun , Wong Nai-Kei , Huang YuanChun 
Published: August 2021

Abstract
Purpose: This study aims to characterize antimicrobial resistance (AMR), with particular reference to carbapenems and aminoglycosides, in MDR A. baumannii isolates recovered from an intensive care unit in a tertiary hospital. Methods: A. baumannii (n = 95 strains) isolated from patients were subjected to antimicrobial susceptibility test (AST) by Vitek 2 Compact system to determine minimum inhibitory concentrations, followed by genotyping by enterobacterial repetitive intergenic consensus-PCR (ERIC-PCR). Resistance genes of interest were PCR-amplified and sequenced. Results: All isolates were qualified as MDR, with a resistance rate of >80% to 8 antimicrobials tested. In terms of beta-lactamase detection, the blaOXA23 and blaTEM-1 genes were detected frequently at 92.63% and 91.58%, respectively. The metallo-β-lactamase genes blaIMP, blaVIM, and blaNDM were undetected. Aph (3’)-I was detected in 82 isolates (86.32%), making it the most prevalent aminoglycoside-modifying enzyme (AMEs) encoding gene. In addition, ant (3”)-I was detected at 30.53%, while 26.32% of the strains harboured an aac (6')-Ib gene. ERIC-PCR typing suggested moderate genetic diversity among the isolates, which might be organized into 10 distinct clusters, with Cluster A (n = 86 isolates or 90.53%) being a dominant cluster of epidemic clones.Conclusions: Substantial fractions of the A. baumannii strains prevailing in the ICU were MDR clones exhibiting extremely high resistance to carbapenems and aminoglycosides as monitored throughout the study period. They principally belonged to a single cluster of isolates carrying blaOXA23 and armA co-producing different AMEs genes.
The Cryoprotective Potential of Propolis Supplemented in Frozen-Thawed Bull Semen: Biochemical and Physiological Findings
Authors: Yeni Deniz , Gülhan Mehmet Fuat , İnanç Muhammed Enes , Avdatek Fatih , Güngör Şükrü , Türkmen Ruhi , Tuncer Pürhan Barbaros , Tasdemir Umut 
Published: August 2021

Abstract
In this study, the cryoprotective effect of different doses of propolis (P) on bull semen, which has strong pharmacological properties thanks to its rich phenolic components, was investigated biochemically and physiologically. Semen samples were collected from Simmental breed bulls via the artificial vagina and pooled. After dividing into five groups, control (C: no additive), and four different dose P (200, 100, 50, and 25 μg/mL) groups, the final concentration was diluted to 16×106 per straw. Semen samples were equilibrated at 4°C for approximately 4 hours, then placed in French straws and frozen. After thawing, sperm motility and kinetic parameters, DNA integrity by single-cell gel electrophoresis, sperm abnormalities by liquid fixation, and lipid peroxidation levels by the colorimetric method was analyzed by Computer-Assisted Semen Analyzer. P added to the diluent showed no effect on motility and kinetic parameters at P25 and P50 (p &gt;0.05), while P100 and P200 had a negative effect (p &lt;0.001). The addition of P (25 and 50) had a treatment effect on tail abnormality compared to C (p &lt;0.05). Especially P50 had a positive effect on tail length, tail DNA, and tail moment, while P100 and P200 caused DNA damage (p &lt;0.001). MDA levels increased in all P dose groups compared to C (p &lt;0.001). This study has clearly demonstrated that P25 and P50 supplements could be used therapeutically in the treatment of sperm abnormalities and prevention of DNA damage in post-thawed bull sperm.
Fine Mapping of A QTL Locus (QNFSP07-1) And Analysis of Candidate Genes For Four-Seeded Pods In Soybean
Authors: Li Yingying , Liu Chunyan , Wang Nannan , Zhang Zhanguo , Hou Lilong , Xin Dawei , Qi Zhaoming , Li Candong , Yu Yan , Jiang Hongwei , Chen Qingshan 
Published: August 2021

Abstract
The number of four-seeded pods is a quantitative trait in soybean [Glycine max (L.) Merr.] and is closely related to yield in terms of breeding. In this study, individuals with high ratio of four-seed pods which from chromosome segment substitution lines (CSSLs) that can be stably inherited were selected as the parent, and Suinong 14 (SN14) was used as recurrent parent to construct secondary mapping population via marker-assisted selection. The initial QTL mapping interval was 0.67 Mb and was located on Gm07. Based on the initial QTL mapping results, individuals that were heterozygous at the interval (36116118-37399738 bp) were screened, and the heterozygous individuals were subjected to inbreeding to obtain 13 F3 populations, with a target interval of 321 kb. Gene annotation was performed on the finely mapped interval, and 27 genes were obtained. Glyma.07G200900, Glyma.07G201200 were identified as candidate genes. qRT-PCR was used to measure the expression of the candidate genes at different developmental stages of soybean. The expression levels of the 2 candidate genes in terms of cell division (axillary buds, COTs, EMs) were higher than those in terms of cell expansion (MM, LM), and these genes play a positive regulatory role in the formation of four-seeded pods. Haplotype analysis shows that Glyma.07G201200 has two excellent haplotypes. Those results provide the information for gene map-based cloning and molecular marker assisted breeding of the number of four-seeded pod in soybean.
Food Insecurity is Associated with Additional Severe Maternal Hardships during Pregnancy: Results from the 2012-2014 California Maternal Infant Health Assessment
Authors: Laraia Barbara , Gamb Ryan , Saraiva Carina , Dove Melanie , Marchi Kristen , Braveman Paula 
Published: August 2021

Abstract
Background: Assess the associations between food insecurity and ten additional maternal hardships experienced during pregnancy.Methods: Data on 14,274 low-/middle-income women from the statewide-representative 2010-2012 California Maternal and Infant Health Assessment were used to estimate food security status and prevalence of additional maternal hardships. Multinomial logistic regression was used to assess the associations between food security status—secure, marginal, low and very low—and these hardships. Results: Food insecurity was common (23%) among all pregnant women in California. Among women with incomes at or below 400% of the income to federal poverty guideline ratio, nine of ten hardships were independently associated with food security status; only the respondent or someone close to the respondent having a problem with alcohol or drugs was not independently associated with food security status after adjusting for socioeconomic factors. Husband/partner losing a job, depressive symptoms, not having practical support and intimate partner violence were consistently associated with marginal, low and very low food security status. Each additional severe maternal hardship a woman experienced during pregnancy was associated with a 36% greater risk of reporting marginal food security (Relative Risk Ratio 1.36, 95% CI: 1.27, 1.47), 54% for low food security (Relative Risk Ratio 1.54, 95% CI: 1.44, 1.64), and 99% for very low food security (Relative Risk Ratio 1.99, 95% CI: 1.83, 2.15). Conclusions: Food security status was strongly linked with several serious maternal hardships that could jeopardize maternal and/or infant health. Policy implications: Services—including prenatal care and nutritional assistance—for a large proportion of pregnant women should address a wide range of serious unmet social needs including food insecurity.Significance Statement: During pregnancy, food insecurity is common and is strongly associated with additional severe maternal hardships that could threaten maternal and infant health.