bluuebunny/crossref_metadata_2025_split huggingface dataset:
Business value of cognitive analytics technology: a dynamic capabilities perspective
Authors: Majhi Siddharth Gaurav , Mukherjee Arindam , Anand Ambuj 
Published: October 2021

Purpose
Novel and emerging technologies such as cognitive analytics attract a lot of hype among academic researchers and practitioners. However, returns on investments in these technologies are often poor. So, identifying mechanisms through which cognitive analytics can add value to firms is a critical research gap. The purpose of this paper is to theorize how cognitive analytics technologies can enable the dynamic capabilities of sensing, seizing and reconfiguring for an organization.

Design/methodology/approach
This conceptual paper draws on the extant academic literature on cognitive analytics and related technologies, the business value of analytics and artificial intelligence and the dynamic capabilities perspective, to establish the role of cognitive analytics technologies in enabling the sensing, seizing and reconfiguring capabilities of an organization.

Findings
Through arguments grounded in existing conceptual and empirical academic literature, this paper develops propositions and a theoretical framework linking cognitive analytics technologies with organizations’ dynamic capabilities (sensing, seizing and reconfiguring).

Research limitations/implications
This paper has critical implications for both academic research and managerial practice. First, the authors develop a framework using the dynamic capabilities theoretical perspective to establish a novel pathway for the business value of cognitive analytics technology. Second, cognitive analytics is proposed as a novel antecedent of the dynamic organizational capabilities of sensing, seizing and reconfiguring.

Originality/value
To the best of the authors’ knowledge, this is the first paper to theorize how cognitive analytics technologies can enable dynamic organizational capabilities, and thus add business value to an organization.
Medicine and the Body in Second‐Wave Feminist Histories of the Nineteenth Century
Authors: ARNOLD‐FORSTER AGNES 
Published: October 2021

AbstractThe 1970s was a crucial decade in the historiography of medicine, and it also witnessed a new political movement. This article will explore the relationship between medical history and second‐wave feminism and argue that 1970s feminists made the idea of the nineteenth century and its medical system work for their political cause. Not only did many of them find in that century the origin point of their own conflict with the medical profession, they also claimed that the medical care they received was founded on the form and methodologies of medical knowledge that arose in the 1800s. Moreover, I contend that the importance of the nineteenth century to many feminist scholars was related to second‐wave feminism's reassertion of the physical body in the construction of personal identity and its related privileging of embodied, experiential knowledge over objective or disembodied forms of expertise.
Influence function methods to assess the effectiveness of influenza vaccine with survey data
Authors: Tian Mingmei , Yu Jihnhee , Lillvis Denise F. , Vexler Albert 
Published: October 2021

AbstractObjectiveTo examine a robust relative risk (RR) estimation for survey data analysis with ideal inferential properties under various model assumptions.Data sourcesWe employed secondary data from the Household Component of the 2000–2016 US Medical Expenditure Panel Survey (MEPS).Study designWe investigate a broad range of data‐balancing techniques by implementing influence function (IF) methods, which allows us to easily estimate the variability for the RR estimates in the complex survey setting. We conduct a simulation study of seasonal influenza vaccine effectiveness to evaluate these approaches and discuss techniques that show robust inferential performance across model assumptions.Data collection/Extraction methodsDemographic information, vaccine status, and self‐administered questionnaire surveys were obtained from the longitudinal data files. We linked this information with medical condition files and medical event to extract the disease type and associated expenditures for each medical visit. We excluded individuals who were 18 years or younger at the beginning of each panel.Principal findingsUnder various model assumptions, the IF methods show robust inferential performance when the data‐balancing procedures are incorporated. Once IF methods and data‐balancing techniques are implemented, contingency table‐based RR estimation yields a comparable result to the generalized linear model approach. We demonstrate the applicability of the proposed methods for complex survey data using 2000–2016 MEPS data. When employing these methods, we find a significant, negative association between vaccine effectiveness (VE) estimates and influenza‐incurred expenditures.ConclusionsWe describe and demonstrate a robust method for RR estimation and relevant inferences for influenza vaccine effectiveness using MEPS data. The proposed method is flexible and can be extended to weighted data for survey data analysis. Hence, these methods have great potential for health services research, especially when data are nonexperimental and imbalanced.
Transitioning to renewable energy in Sydney: Relational and co‐evolving energy geographies
Authors: Vaughan Alexander , Webber Sophie 
Published: October 2021

AbstractThis article analyses the geographies and politico‐economic dynamics of Sydney’s multiscalar renewable energy transition. Sydney’s energy economy seems to be dominated by marketisation, privatisation, and fossil fuel‐generated electricity, yet simultaneously a decentralised renewable energy transformation is unfolding. In this context, we ask how do politico‐economic and technical changes co‐evolve within the renewable energy transition? What tensions exist among different actors, institutions, and markets across changing energy geographies? Drawing from field research, including key informant interviews with various renewable energy stakeholders, we characterise the renewable energy transition in Sydney as inherently relational and in tension rather than as simplistically binary. In particular, three dynamics of relationality considered here are foundational in the push and pull of energy geographies in Sydney: fossil fuels and renewable energy sources; neoliberalisation and democratisation; and system and local scales as sites of action. After mapping those out, we conclude by questioning the long‐term impact of neoliberalisation on emergent, more democratic approaches to energy.
Anti‐proliferative activity of Ensete superbum Roxb. Cheesman extract and its active principles on human colorectal cancer cell lines
Authors: Mathew Nimisha Sarah , Kurrey Nawneet Kumar , Bettadaiah Bheemanakere Kempaiah , Negi Pradeep Singh 
Published: October 2021

AbstractEnsete superbum Roxb. Cheesman (wild banana) is a plant traditionally used for the treatment of fever and diarrhea. On a preliminary screening, the ripe peel aqueous extract (PA) exhibited higher cytotoxicity (cell viability of 49% against HCT‐15 at 75 µg/ml; and 46% against Caco2 at 50 µg/ml), superior anti‐inflammatory (IC50 of 0.49 µg/ml), and greater anti‐mutagenic activity at 500 µg/plate compared to the aqueous extracts of seed (SA), flower (FA) and bract (BA). Therefore, we further evaluated the anti‐proliferative activity of PA and its fractions. The ability to inhibit the growth of cell lines (HCT‐15 and Caco2) was used for the bio‐guided fractionation and isolation of active compounds in PA using chromatographic techniques. Multiple extractions of the PA yielded the peel dioxane fraction (PD), and column fractionation of PD yielded eight compounds, of which three (Compound D—PDD, Compound E—PDE, and Compound G—PDG) possessed higher cytotoxic activity. At 10 µg/ml, the cell viability of HCT‐15 was 50.1%, 46.5%, and 61.9%, respectively; Caco2 was 98.2%, 62.9%, and 64.7%, respectively, for PDD, PDE, and PDG. These compounds also showed apoptotic effect as evidenced by measuring the mitochondrial membrane potential, dual staining (acridine orange/ethidium bromide), DNA fragmentation, and the ROS status in colorectal cell lines. The UPLC‐HRMS/MS, FTIR, and NMR data revealed the active compounds as quercetin‐3‐O‐rutinoside, 3,5‐dimethoxy‐4‐hydroxybenzoic acid, and 4′,5,7‐trihydroxyflavone. These findings indicate the anti‐proliferative potential of PA, and warrant further investigation of its active principles in the amelioration of colorectal cancer in in vivo models.Practical ApplicationThe potential of an underutilized crop as a source of therapeutic agents for colon cancer was established, as the study showed a high cytotoxic activity of wild bananas against HCT‐15 and Caco2 cell lines. Bioactivity guided fractionation of peel fraction identified the active compounds present in wild banana, and their anticancer activity was attributed to the induction of cell death. The study indicated that wild banana has the potential to inhibit the growth of colon cancer cells.
Cavernous sinus thrombosis followed by brain ischaemia in a type‐1 diabetic patient: a persistent endodontic infection report
Authors: Pereira Rodrigo S. , Guerra Raphael C. , Hochuli‐Vieira Eduardo , Alves Flávio R. F. 
Published: October 2021

AbstractCentral nervous system infections and cavernous sinus thrombosis are associated with high mortality rates and may be a consequence of oral infection propagation. A 24‐year‐old woman has attended a private dental office with a pain complaint in the upper right central incisor and had the endodontic treatment completed. However, the patient returned to the dental office reporting pain in the same tooth and the presence of swelling. Then, the root canal was retreated. After one week, the patient presented to a Basic Health Unit with a history of vomiting and convulsion crisis followed by loss of consciousness. A computed tomography exam showed cavernous sinus thrombosis and brain ischaemic areas. The present report describes a rare case of cavernous sinus thrombosis followed by brain ischaemia in a type‐1 diabetic patient, associated with persistent endodontic infection, with subsequent patient’s death.
“Why do dogs pant?”: Characteristics of parental explanations about science predict children's knowledge
Authors: Mills Candice M. , Danovitch Judith. H. , Mugambi Victoria N. , Sands Kaitlin R. , Pattisapu Fox Candice 
Published: October 2021

AbstractUsing a new method for examining parental explanations in a laboratory setting, the prompted explanation task, this study examines how characteristics of parental explanations about biology relate to children's knowledge. Parents (N = 148; Mage = 38; 84% female, 16% male; 67% having completed college) of children ages 7–10 (Mage = 8.92; 47% female, 53% male; 58% White, 9.5% Black, 9.5% Asian) provided answers to eight how and why questions about biology. Parents used a number of different approaches to address the questions, including providing more mechanistic responses to how questions and more teleological responses to why questions. The characteristics of parental explanations—most notably, how frequently parents provided correct responses—predicted children's performance on measures of verbal intelligence and biological knowledge. Additional exploratory analyses and implications for children's learning are discussed.
Influence of renewable energy sources on the scheduling on thermal power stations and its optimization forCO2reduction
Authors: Mathi Ramalingam , Jayalalitha Subbaiahan 
Published: October 2021

AbstractThe thermal power of the total power demand accounts for the total of 60% in India, with the penetration of the nonconventional energy sources the grid management becomes a tedious job in maintaining the grid stability, and adding to the woes the environmental norms become stricter as it is a tough job to maintain to lesser CO2emissions in the atmosphere. Hence this article aims with the integration of the grid management with the renewable energy sources and reduction of CO2and also strives for the grid stability with the smart grid. And the thermal scheduling optimization is done with the novel bat algorithm.
1008. STIGMATODACTYLUS DALAGANGPALAWANICUM: Orchidaceae
Authors: S. Robinson Alastair 
Published: October 2021

SummaryStigmatodactylus dalagangpalawanicum A.S. Rob. is a miniature orchid endemic to the highest reaches of the ultramafic Mount Victoria massif in central Palawan, the Philippines. Its habitat and ecology are described and additional background to this relatively poorly documented genus provided.
Long‐term ecosystem nitrogen limitation from foliar δ15N data and a land surface model
Authors: Caldararu Silvia , Thum Tea , Yu Lin , Kern Melanie , Nair Richard , Zaehle Sönke 
Published: October 2021

AbstractThe effect of nutrient availability on plant growth and the terrestrial carbon sink under climate change and elevated CO2 remains one of the main uncertainties of the terrestrial carbon cycle. This is partially due to the difficulty of assessing nutrient limitation at large scales over long periods of time. Consistent declines in leaf nitrogen (N) content and leaf δ15N have been used to suggest that nitrogen limitation has increased in recent decades, most likely due to the concurrent increase in atmospheric CO2. However, such data sets are often not straightforward to interpret due to the complex factors that contribute to the spatial and temporal variation in leaf N and isotope concentration. We use the land surface model (LSM) QUINCY, which has the unique capacity to represent N isotopic processes, in conjunction with two large data sets of foliar N and N isotope content. We run the model with different scenarios to test whether foliar δ15N isotopic data can be used to infer large‐scale N limitation and if the observed trends are caused by increasing atmospheric CO2, changes in climate or changes in sources and magnitude of anthropogenic N deposition. We show that while the model can capture the observed change in leaf N content and predict widespread increases in N limitation, it does not capture the pronounced, but very spatially heterogeneous, decrease in foliar δ15N observed in the data across the globe. The addition of an observation‐based temporal trend in isotopic composition of N deposition leads to a more pronounced decrease in simulated leaf δ15N. Our results show that leaf δ15N observations cannot, on their own, be used to assess global‐scale N limitation and that using such a data set in conjunction with an LSM can reveal the drivers behind the observed patterns.
Revisiting ‘America's Penal Experiments’ 100 Years Later
Authors: RUBIN ASHLEY T. 
Published: October 2021

AbstractIn 1921, American prison administrator and reformer, Spencer Miller, was invited to describe America's recent penal developments to the Howard League for Penal Reform. This article reviews the context of Progressive Era American prisons to better understand Miller's remarks and their lessons for prison administrators and reformers today. It briefly describes the history of American prisons into the Progressive Era as well as some developments that were most relevant to Miller, viz., the reforms at Sing Sing under famed penal reformer and warden, Thomas Mott Osborne. Next, the article reviews Miller's statement to the Howard League for Penal Reform, including his inaccurate description of prison history, which can be read as a means of emphasising the extraordinary progress made by Osborne and, implicitly, by Miller at Sing Sing and as an example to the nation. Finally, it discusses Miller's abolitionism in the context of similar discussions taking place today.
Corrupting and Saving: Moral Contamination, Prison Education and Prison History
Authors: JOHNSTON HELEN 
Published: October 2021

AbstractThis article examines the ways in which prison has been seen as both a ‘school of crime’ and a school of reform; a place for potential further corruption, or through education in prison, a route away from criminality. It explores the methods used, since the early 19th Century, to protect those confined from the corrupting prison environment. In examining prison education in the 1920s, it argues that, despite significant changes in the wider penal system, changes in education and schooling within prison walls, continued to be slow, protracted in developing, and ineffectual in the challenge of reforming prisoners.
The modification of the thrombin generation assay for the clinical assessment of hypercoagulability in patients receiving heparin therapy
Authors: Benoit Remi , Nougier Christophe , Desmurs‐Clavel Helene , Simon Marie , Dargaud Yesim 
Published: October 2021

AbstractBackgroundHeparin diminishes thrombin generation (TG) because it decreases the survival time of thrombin in plasma. Under heparin therapy, the TG curve therefore does not reflect the true hemostatic status of the patient.AimWe investigated how far the in vitro addition of a heparin antagonist can restore the underlying TG capacity.Materials & MethodsFive different heparin antagonists were tested: polybrene, protamine sulfate, heparinase type 1, heparinase HEP‐TEM, and (Z‐GGR)2‐rhodamine (P2Rho).Results and ConclusionPolybrene, P2Rho, and heparinase HEP‐TEM effectively neutralized heparin at prophylactic and therapeutical doses of both low molecular weight and unfractionated heparin. The advantages and limits of each molecule and the most favorable combinations of TG‐trigger and antagonist are discussed.
Virtual reality interventions and the outcome measures of adult patients in acute care settings undergoing surgical procedures: An integrative review
Authors: Wang Shuli , Lim Siew Hoon , Aloweni Fazila Binte Abu Bakar 
Published: October 2021

AbstractAimsTo evaluate the different types of virtual reality (VR) therapy received by adult patients undergoing surgical procedures in acute care settings and the outcome measures, as well as to highlight the acceptability and feasibility of VR approaches among patients and healthcare workers.DesignWhittemore and Knafl's integrative review method guided the analysis.Data sourcesSearches were conducted in ScienceDirect, ProQuest, Wiley Online Library, Medline, PsycINFO and PubMed and Google Scholar from 2000 to June 2021.Review methodsA systematic search on articles published in English was carried out with electronic databases and hand search references. Keywords searched included primary qualitative and quantitative studies that utilized VR therapy in surgical care settings.ResultsEighteen articles were reviewed, which reported the use of two main strategies: guided and interactive imagery therapy. The findings identified: (i) patient‐clinical outcome measures including the use of analgesics, vital signs, functional capacity and length of hospital stay; and (ii) patient‐reported experience measures including pain, anxiety and satisfaction level. Comfort, age, knowledge and attitude were key factors influencing the acceptability of VR among the patients, whereas cost‐effectiveness and infection control were two main factors affecting the feasibility of use among the health care workers.ConclusionVR therapy demonstrated potential improvements in both the patient‐clinical outcomes and patient‐reported experiences of those undergoing surgical procedures. However, the findings were inconsistent, which required further research to explore and establish the effectiveness of using VR in the context of acute care settings.ImpactVR distraction has been increasingly used as a non‐pharmacological method in managing pain, easing anxiety and optimizing other associated outcomes in patients undergoing surgical procedures. It is essential to examine the effectiveness of VR therapy on the adult patients’ outcomes in acute care settings with surgical procedures, as well as its acceptability and feasibility of use.
Transgenic approaches to opening up new fields of vasopressin and oxytocin research
Authors: Ueta Yoichi 
Published: October 2021

AbstractTransgenic approaches have been applied to generate transgenic rats that express exogenous genes in arginine vasopressin (AVP)‐ and oxytocin (OXT)‐producing magnocellular neurosecretory cells (MNCs) of the hypothalamic‐neurohypophyseal system (HNS). First, the fusion gene that expresses AVP‐enhanced green fluorescent protein (eGFP) and OXT‐monomeric red fluorescent protein 1 (mRFP1) was used to visualize AVP‐ and OXT‐producing MNCs and their axon terminals in the HNS under fluorescence microscopy. Second, the fusion gene that expresses c‐fos‐eGFP and c‐fos‐mRFP1 was used to identify activated neurons physiologically in the central nervous system, including MNCs, circumventricular organs and spinal cord. In addition, AVP‐eGFP x c‐fos‐mRFP1 and OXT‐mRFP1 × c‐fos‐eGFP double transgenic rats were generated to identify activated AVP‐ and OXT‐producing MNCs using appropriate physiological stimuli. Third, the fusion gene that expresses AVP‐chanelrhodopsin 2 (ChR2)‐eGFP and AVP‐hM3Dq‐mCherry was used to activate AVP‐ and OXT‐producing MNCs by optogenetic and chemogenetic approaches. In each step, these transgenic approaches in rats have provided new insights on the physiological roles of AVP and OXT not only in the HNS, but also in the whole body. In this review, we summarize the transgenic rats that we generated, as well as related physiological findings.
Exploring optimal stomatal control under alternative hypotheses for the regulation of plant sources and sinks
Authors: Dewar Roderick , Hölttä Teemu , Salmon Yann 
Published: October 2021

Summary

Experimental evidence that nonstomatal limitations to photosynthesis (NSLs) correlate with leaf sugar and/or leaf water status suggests the possibility that stomata adjust to maximise photosynthesis through a trade‐off between leaf CO2 supply and NSLs, potentially involving source–sink interactions. However, the mechanisms regulating NSLs and sink strength, as well as their implications for stomatal control, remain uncertain.

We used an analytically solvable model to explore optimal stomatal control under alternative hypotheses for source and sink regulation. We assumed that either leaf sugar concentration or leaf water potential regulates NSLs, and that either phloem turgor pressure or phloem sugar concentration regulates sink phloem unloading.

All hypotheses led to realistic stomatal responses to light, CO2 and air humidity, including conservative behaviour for the intercellular‐to‐atmospheric CO2 concentration ratio. Sugar‐regulated and water‐regulated NSLs are distinguished by the presence/absence of a stomatal closure response to changing sink strength. Turgor‐regulated and sugar‐regulated phloem unloading are distinguished by the presence/absence of stomatal closure under drought and avoidance/occurrence of negative phloem turgor. Results from girdling and drought experiments on Pinus sylvestris, Betula pendula, Populus tremula and Picea abies saplings are consistent with optimal stomatal control under sugar‐regulated NSLs and turgor‐regulated unloading.

Our analytical results provide a simple representation of stomatal responses to above‐ground and below‐ground environmental factors and sink activity.