bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identifying the causal relationship between gut microbiota and lymphoma disease: a Mendelian randomization study and meta-analysis
Authors: Huang Ruizhe , Liu Boyi , Zhang Wenchao , Tian Jie , Yu Kaiwei , Chen Danna 
Published: February 2025

IntroductionIncreasing evidence from observational studies and clinical trials suggests that gut microbiota (GM) are associated with lymphoma. However, it is unclear whether there is a causal relationship between GM and lymphoma.Material and methodsTo evaluate the causal relationship between GM and lymphoma, we conducted a two-sample Mendelian randomization analysis based on the genome-wide association study (GWAS). GWAS summary statistics of the GM were obtained from the MiBioGen study that including 211 taxa. GWAS summary statistics of four lymphomas were obtained from the IEU Open GWAS study. Then, we systematically performed sensitivity analyses and heterogeneity analysis to verify the reliability of our findings. Finally, we used an external cohort for validation and performed a meta-analysis of the positive results.ResultsWe identified 37 causal relationships between GM and lymphoma. The results of the sensitivity analyses demonstrated the reliability of the MR analysis. Furthermore, the combined meta-analysis yielded nine significant results, with the most notable being Terrisporobacter (MetaOR = 2.39, 95% CI = 1.07–5.32, p = 0.03), which was identified as a pathogenic factor for diffuse large B-cell lymphoma (DLBCL). Methanobrevibacter (MetaOR = 0.49, 95% CI = 0.27–0.92, p = 0.03) was identified as a protective factor against DLBCL. Cyanobacteria (MetaOR = 1.94, 95% CI = 1.24–3.03, p = 0.004) were identified as a pathogenic factor for FL.ConclusionsOur study identified a causal relationship between gut microbes and four lymphoma diseases. To further confirm the causal relationship, external validation was performed, thereby providing new insights into the subsequent mechanisms by which gut microbes mediate lymphoma development.
Uncertainty in the projected Antarctic contribution to sea level due to internal climate variability
Authors: Caillet Justine , Jourdain Nicolas C. , Mathiot Pierre , Gillet-Chaulet Fabien , Urruty Benoit , Burgard Clara , Amory Charles , Chekki Mondher , Kittel Christoph 
Published: February 2025

Abstract. Identifying and quantifying irreducible and reducible uncertainties in the Antarctic Ice Sheet (AIS) response to future climate change is essential for guiding mitigation and adaptation policy decision. However, the impact of the irreducible internal climate variability, resulting from processes intrinsic to the climate system, remains poorly understood and quantified. Here, we characterise both the atmospheric and oceanic internal climate variability in a selection of three Coupled Model Intercomparison Project Phase 6 (CMIP6) models (UKESM1-0-LL, IPSL-CM6A-LR, and MPI-ESM1.2-HR) and estimate their impact on the Antarctic contribution to sea-level change over the 21st century under the SSP2-4.5 scenario. To achieve this, we use a standalone ice-sheet model driven by the ocean through parameterised basal melting and by the atmosphere through emulated surface mass balance estimates. The atmospheric component of internal climate variability in Antarctica has a similar amplitude in the three CMIP6 models. In contrast, the amplitude of the oceanic component strongly depends on the climate model and its representation of convective mixing in the ocean. A low bias in sea-ice production and an overly stratified ocean lead to a lack of deep convective mixing which results in weak ocean variability near the entrance of ice-shelf cavities. Internal climate variability affects the Antarctic contribution to sea-level change until 2100 by 45 % to 93 % depending on the CMIP6 model. This may be a low estimate, as the internal climate variability in the CMIP models is likely underestimated. The effect of atmospheric internal climate variability on the surface mass balance overwhelms the effect of oceanic internal climate variability on the dynamical ice-sheet mass loss by a factor of 2 to 5, except in the Dronning Maud area and the Amundsen, Getz, and Aurora basins, where both contributions may be similar depending on the CMIP model. Based on these results, we recommend that ice-sheet model projections consider (i) several climate models and several members of a single climate model to account for the impact of internal climate variability and (ii) a longer temporal period when correcting historical climate forcing to match present-day observations.
Enhancing human–robot collaboration with thermal images and deep neural networks: the unique thermal industrial dataset WLRI-HRC and evaluation of convolutional neural networks
Authors: Süme Sinan , Ponomarjova Katrin-Misel , Wendt Thomas M. , Rupitsch Stefan J. 
Published: February 2025

Abstract. This contribution introduces the use of convolutional neural networks to detect humans and collaborative robots (cobots) in human–robot collaboration (HRC) workspaces based on their thermal radiation fingerprint. The unique data acquisition includes an infrared camera, two cobots, and up to two persons walking and interacting with the cobots in real industrial settings. The dataset also includes different thermal distortions from other heat sources. In contrast to data from the public environment, this data collection addresses the challenges of indoor manufacturing, such as heat distortions from the environment, and allows for it to be applicable in indoor manufacturing. The Work-Life Robotics Institute HRC (WLRI-HRC) dataset contains 6485 images with over 20 000 instances to detect. In this research, the dataset is evaluated for implementation by different convolutional neural networks: first, one-stage methods, i.e., You Only Look Once (YOLO v5, v8, v9 and v10) in different model sizes and, secondly, two-stage methods with Faster R-CNN with three variants of backbone structures (ResNet18, ResNet50 and VGG16). The results indicate promising results with the best mean average precision at an intersection over union (IoU) of 50 (mAP50) value achieved by YOLOv9s (99.4 %), the best mAP50-95 value achieved by YOLOv9s and YOLOv8m (90.2 %), and the fastest prediction time of 2.2 ms achieved by the YOLOv10n model. Further differences in detection precision and time between the one-stage and multi-stage methods are discussed. Finally, this paper examines the possibility of the Clever Hans phenomenon to verify the validity of the training data and the models’ prediction capabilities.
Pemberian Psikoedukasi sebagai Upaya Meningkatkan Pengetahuan dan Kesadaran Terhadap Konseling dan Permasalahan Suicide pada Karyawan Instansi X Sumatera Selatan
Authors: Azkarina Meiska , Maharani Aisyah , Lestari Biancha Anisyah , Inayah Shifa , Appulembang Yeni Anna 
Published: February 2025

Pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan dan kesadaran komunitas terkait permasalahan yang terjadi di lingkungan instansi X. Metode penelitian dilakukan melalui asesmen, yaitu observasi tidak terstruktur dan juga pengumpulan data sekunder, lalu peningkatan pengetahuan dan kesadaran melalui metode psikoedukasi. Psikoedukasi dilakukan dalam bentuk pembuatan poster suicide prevention awareness dan banner “Ayo konseling” yang ditempatkan di lingkungan instansi X. Hasil psikoedukasi ini berguna untuk memberikan informasi terkait permasalahan konseling dan meningkatkan kepedulian akan tanda-tanda bunuh diri yang mungkin terjadi dan menjadi pendukung fasilitas di Bagian Psikologi biro SDM instansi X, hal ini dibuktikan salah satunya dengan kenaikan dalam jumlah karyawan yang datang untuk melakukan konseling pada tahun 2024 sekitar 15% lebih banyak dari keseluruhan data di tahun 2023.
The Discordance Between Pain and Imaging in Knee Osteoarthritis
Authors: Hill Brandon G. , Eble Stephanie , Moschetti Wayne E. , Schilling Peter L. 
Published: February 2025

Introduction:
Clinicians use imaging studies to help gauge the degree to which structural factors within the knee account for patients' pain and symptoms. We aimed to determine the degree to which commonly used structural features predict a patient's knee pain and symptoms.

Methods:
Using Osteoarthritis Initiative data, a 10-year study of 4,796 patients with knee osteoarthritis (KOA), participants' KOA was characterized by radiographs and MRI scans of the knee. Salient features were quantified with two established grading systems: (1) individual radiographic features (IRFs) and (2) MRI Osteoarthritis Knee Scores (MOAKS) from MRI scans. We paired participants' IRFs (24,256 readings) and MOAKS (2,851 readings) with side-specific Knee Injury and Osteoarthritis Outcome Scores (KOOS). We trained generalized linear models to predict KOOS from features measured in IRF and MOAKS. We repeated the analysis on four subsets of the cohort. The models' predictive performance was evaluated using root mean square errors and coefficient of determination (R2).

Results:
Neither radiographic features used to determine IRF grades nor MOAKS were predictive of patient pain or symptoms. MOAKS's performance was slightly more predictive of KOOS than IRF's. IRF's prediction of KOOS achieved a maximum R2 of 0.15 and 0.28 for MOAKS, indicating a low level of accuracy in predicting the target variable.

Discussion:
Commonly used structural features from radiographs and MRI scans cannot predict KOA pain and symptoms—even when imaging features are codified by established grading systems like IRF or MOAKS. The predictive performance of these models is even worse as symptom severity worsens.

Level of Evidence:
IV
TO‘PLAMLAR USTIDA BAJARILADIGAN MINKOVSKIY AMALLARINI O‘QITISHNING ZAMONAVIY METODLARI
Authors: Nuritdinov Jalolxon , Tashxodjayev Abdug‘affor 
Published: February 2025

Mazkur maqolada Minkovskiy operatorlarining xususiy hollari bo‘lgan to‘plamlar ustida bajariladigan Minkovskiy amallarini o‘qitishda qo‘llaniladigan zamonaviy pedagogik texnologiyalar va innovatsion yondashuvlar muhokama qilinadi. Tadqiqot ishida nazariy tahlil, lokal va nolokal differensial geometriya, qatlamalar topologiyasi, qatlamalar nazariyasi va dinamik sistemalar nazariyasining geometrik hamda topologik usullaridan foydalanilgan. Ushbu maqolada to‘g‘ri chiziqda va tekislikda berilgan to‘plamlarning Minkovskiy yig‘indisi va ayirmasini hisoblashning turli usullari keltiriladi. Ushbu usullarni talabalarga o‘rgatishda qo‘llanilishi mumkin bo‘lgan metodlar, xususan, axborot texnologiyalaridan foydalanish, vizualizatsiya va interaktiv dasturlar yordamida darslarni boyitish yo‘llari tahlil qilinadi.
O‘ZBEKISTONDA YOSHLAR IJTIMOIYLASHUVIDA MILLIY-SIYOSIY MENTALITETNING O‘RNI
Authors: Yusupov Axrorjon 
Published: February 2025

Mazkur maqolada Mustaqillik yilarida O‘zbekistonda yoshlar ijtimoiylashuvida milliy-siyosiy mentalitetning o‘rni, yoshlarning siyosiy madaniyatini rivojlantirishning mafkuraviy omillari tashkil etishning huquqiy asoslarini mustahkamlanishi, yoshlarga oid davlat siyosatini takomillashtirish uchun respublikada olib borilgan islohatlar, qarorlar, farmonlar va ularning amaldagi natijalari ilmiy asosda tahlil etilgan. Maqolada tadqiq etilayotgan mavzu yuzasidan N.E.Soliyeva, X.I.Abduraxmonovlar tadqiqot ishlarini olib borgan bo‘lib, mazkur tadqiqotlarda O’zbekistonda yoshlar siyosiy faolligi, yoshlar ijtimoiylashuvida milliy-siyosiy mentalitetning o‘rni, siyosiy madaniyati, ma’naviy-mafkuraviy omillarini rivojlantirish o‘rganilgan. A.A.Jalilov, A.Z.Sharipov tomonidan esa yoshlarning innovatsion-kreativ yondashuvlari mustaqillik yillardagi jarayonlari umumiy tarzda tahlil etilgan. Mazkur ishimizda yuqorida sanab o‘tilgan tadqiqotchilarning ishlari muhim manbaviy asos bo‘lib xizmat qiladi. Shu sababli biz mazkur maqolada yoshlarning jamiyatimiz boshqaruvida yoshlarning ijtimoiy-siyosiy faolligini tadqiq etishni asosiy maqsad etib qo‘ydik. Shuningdek maqolada mustaqillikning dastlabki yillaridagi respublikadagi va xozirgi kunda yoshlarga etibor aniq tahlillar asosida qiyosiy o‘rganilgan. Shuningdek olingan tahlil natijalari asosida yoshlar faolligini rivojlantirish, samaradorligini oshirishga doir taklif va xulosalar ishlab chiqilgan.
Pendekatan Feminisme dalam Analisis Cerpen “Kunang-Kunang dalam Bir” Karya Djenar Maesa Ayu
Authors: Rauzatul Jannah  
Published: February 2025

This research aims to examine how feminist values ​​are represented in the short story Kunang-Kunang in Bir by Djenar Maesa Ayu. Using descriptive qualitative research methods. Feminist literary criticism allows for in-depth analysis of themes, characters, and symbols related to issues of gender and inequality. In the analysis of this short story, gender inequality, social norms and symbolism were found. The results of this research show women's struggle in facing patriarchal norms and injustice that prevent women from achieving happiness. The symbolism used increases public criticism of ongoing gender inequality. It is hoped that this research can contribute to feminist literary studies and encourage awareness of the importance of women's freedom in making life decisions.
Entre teoria e prática: os conflitos internos nas organizações contrárias à ditadura à luz de militantes e militares
Authors: Alves Herik Eduardo Sousa , Pereira Josieuder Silva , Costa Victor Gabriel de Jesus Santos David 
Published: February 2025

O presente trabalho tem como objetivo discutir o surgimento, as discussões internas e o esfacelamento das organizações que atuaram contra a ditadura civil-militar brasileira instaurada a partir do golpe de 1964, a análise baseia-se na obra Orvil – Tentativas de Tomada de Poder (2012), escrita por militares da década de 1980 e reservada às altas patentes militares, neste estudo a literatura militar tem como objetivo apresentar as narrativas do governo autoritário sobre as organizações de esquerda, em contraponto, serão comparadas as narrativas com a obra Combate nas Trevas (1987), escrita pelo historiador e ex-membro do Partido Comunista Brasileiro, Jacob Gorender, no qual narra os fatos fundamentados na ciência história e na perspectivas dos militantes. O trabalho comparou as narrativas descritas por militares e por militantes em ambas as obras e as discutiu à luz da historiografia, apontando principalmente as inconsistências encontradas na obra escrita pelo tenente-coronel Lício Augusto Ribeiro Maciel e pelo tenente José Conegundes do Nascimento, ambos vinculados ao Centro de Informações do Exército (CIE).
DNA, Diversity and You at Cambridge Science Festival
Authors: Hull Duncan 
Published: February 2025

As part of Cambridge Science festival last weekend, I joined a group of about 40 volunteers from The Sanger and EBI at an event “DNA, diversity and you”. This was a series of education and outreach events designed to explore how differences in your genetic code make you different from other individuals, and what makes the humans different from other living things – with a bit of computational biology thrown in for good measure.
Join us to discuss the tyranny of content on Monday 5th July at 2pm BST
Authors: Hull Duncan 
Published: February 2025

If content is king, then his rule is tyrannical. Bill Gates once remarked that “Content is King” but In the kingdom of education, how much do educators oppressively inflict content on their learners? What can be done to reduce the tyranny of content? We’ll be discussing this via a paper by Christina I. Petersen et al, here’s the abstract: All welcome.
Manchester Digital and Higher Education in 2013
Authors: Hull Duncan 
Published: February 2025

Manchester Digital is the independent trade association for the thriving digital sector in the North West of England. Last night they held their AGM and elections for new members of their council. I was encouraged to stand for election, and alongside 19 other candidates, had to give a two-minute “manifesto” in a husting / lightning-talk format. Here’s roughly what […]
The Silicon Valley Meme: Coming to a Technology Cluster Near You …
Authors: Hull Duncan 
Published: February 2025

… if it hasn’t done already In California the streets aren’t paved with Gold, they are paved with Silicon. Many a Californian has made their fame and fortune from Silicon-based commerce. Facebook, Google, Twitter, Oracle, Apple the list goes on and on. Silicon paves the streets of Silicon Valley. Silly Valley is often imitated but rarely […]
Makey Christmas and a Hacky New Year!
Authors: Hull Duncan 
Published: February 2025

Our homes are full of technology that we typically take for granted and understand little. Your average smartphone or tablet, for example, is a “black box”, that deliberately discourages modification by tinkering and hacking. This Christmas, Danielle George takes three technologies we routinely take for granted – the light bulb, the telephone and the motor – and […]
Be nice to nerds … you may end up working for them
Authors: Hull Duncan 
Published: February 2025

Thought for the day: be nice to nerds because you might end of up working for them. This sound advice comes from DARPA defector and newly appointed Googler Regina Dugan (see picture below). What’s that you say? You’re not sure exactly what a nerd is? There are many definitions but the graphic below sums it up better than the Oxford English Dictionary ever could. But beware!
Nine ideas for teaching Computing at School from the 2017 CAS conference
Authors: Hull Duncan 
Published: February 2025

The Computing At School (CAS) conference is an annual event for educators, mostly primary and secondary school teachers from the public and private sector in the UK. Now in its ninth year, it attracts over 300 delegates from across the UK and beyond to the University of Birmingham, see the brochure for details. One of the purposes […]
Animation 2012: Computer Science for Schools
Authors: Hull Duncan 
Published: February 2025

Computer Science as a subject in mainstream UK secondary education is in a pretty sorry state [1,2,3] but it’s not all doom and gloom. While many long suffering school children are being force-fed a nauseating diet of Excel, PowerPoint and Access others are enjoying a nutritious platter of Raspberry Pi, Hack to the Future and Animated fun.
Who is the World’s Largest Advertising Agency?
Authors: Hull Duncan 
Published: February 2025

Advertising agencies are everywhere, there is no escaping them. But who’s the daddy of the advertising world? The mother of all ad agencies? According to wikipedia, WPP is the “world’s largest advertising group by revenues”. This is hogwash. Some of the world’s largest ad agences are technology companies. For example, in descending order of revenue: Google Inc. is […]
A simple and useable classification of software by Aral Balkan via Wuthering Bytes
Authors: Hull Duncan 
Published: February 2025

It’s getting pretty hard to do anything these days that doesn’t involve software. Our governments, businesses, laboratories, personal lives and entertainment would look very different without the software that makes them tick. How can we classify all this software to make sense of it all? The likes of this huge list of software categories on wikipedia are pretty […]
Análisis de la viabilidad para crear e implementar una empresa sostenible de Autolavado en Seco
Authors: Figueroa Guillen Carlos , De Lara González Norma , Silva Jiménez Diego , González Mendoza Aaron , Ontiveros Ontiveros Martha Verónica 
Published: February 2025

El desarrollo sustentable y sostenible, hoy en día, guarda una estrecha relación respecto al uso moderado de los recursos naturales, uno de estos recursos es el agua, elemento vital para el ser humano. El propósito del presente estudio fue analizar la viabilidad de un proyecto enfocado en la formación y ejecución de un sistema de lavado de autos en seco como un proyecto que contemple el uso y el ahorro eficiente del recurso hídrico. Una investigación cuantitativa de campo, descriptiva y exploratoria, el desarrollo fue a partir del diseño y aplicación de un cuestionario que constó de 17 preguntas a una muestra de 337 automovilistas de las zonas de Colonia Panorama, Colonias del Río, San Cayetano, Bosques y Campestre, de la Ciudad de Aguascalientes, México. Se obtuvo un 83 % de aceptación del proyecto, establecido en $65.00 por servicio. Asimismo, tuvo un flujo neto de efectivo a valor presente neto de $283,128.71, una TREMA calculada en 21.75 % (incluyendo el riesgo al proyecto del 10 %), y una TIR proyectada de 34.76 %, superior a la TREMA. Se concluye que el proyecto es viable y favorece el costo del servicio de autolavado en seco.
Los Espacios de culto como experiencia educativa (I): Fundamentación pedagógica. La Basílica de la Sagrada Familia de Barcelona, un ejemplo paradigmático
Authors: Marín i Torné Francesc-Xavier , Navarro Guareño Angel-Jesús , De Montserrat Vallvé Anna , Aran Sala Eloi , Jarabo Fidalgo Anna Eva 
Published: February 2025

El presente artículo expone la riqueza pedagógica que tienen los espacios religiosos de culto dando muestra especial del magnífico ejemplo paradigmático que a este respecto representa la Basílica de la Sagrada Familia de Barcelona. El propósito principal es manifestar la necesidad de recuperar y reactualizar el uso de los espacios sacros, como espacios educativos vigentes, dado que esto es una urgencia pedagógica, por los beneficios y riqueza didáctica que esos mismos espacios nos proponen, así como por la realidad que hoy en día se da a estos espacios desde la perspectiva pedagógica. Esta tesis se establece, en un primer artículo, desde una fundamentación pedagógica, dando paso a dos artículos más que abordarán las perspectivas arquitectónica y teológica que avalan que los espacios de culto son unos espacios extraordinarios y únicos para generar y desarrollar auténticas experiencias educativas llenas de significado y de oportunidades para la educación del siglo XXI.