bluuebunny/crossref_metadata_2025_split huggingface dataset:
A case series of SARS-CoV-2 reinfections caused by the variant of concern Gamma in Brazil
Authors: Naveca Felipe Gomes , Nascimento Valdinete Alves , Nascimento Fernanda , Ogrzewalska Maria , Pauvolid-Corrêa Alex , Araujo Mia Ferreira , Arantes Ighor , Rocha Batista Érika Lopes , Álvares Magalhães Alessandro Leonardo , Vinhal Fernando , Mattos Tirza Peixoto , Riediger Irina , Carmo Debur Maria do , Grinsztejn Beatriz , Veloso Valdiléa G , Brasil Patricia , Rodrigues Rodrigo Ribeiro , Rovaris Darcita Buerger , Fernandes Sandra Bianchini , Fernandes Cristiano , Abdalla Santos João Hugo , Abdalla Lígia Fernandes , Costa-Filho Rubens , Silva Marineide , Souza Victor , Costa Ágatha Araújo , Mejía Matilde , Brandão Maria Júlia , Gonçalves Luciana Fé , Silva George Allan , de Jesus Michele Silva , Pessoa Karina , Guerra Corado André de Lima , Gomes Duarte Debora Camila , Machado Ana Beatriz , de Azevedo Zukeram Ketiuce , Valente Natalia , Lopes Renata Serrano , Pereira Elisa Cavalcante , Appolinario Luciana Reis , Rocha Alice Sampaio , Lopez Tort Luis Fernando , Sekizuka Tsuyoshi , Itokawa Kentaro , Hashino Masanori , Kuroda Makoto , Wallau Gabriel Luz , Delatorre Edson , Gräf Tiago , Siqueira Marilda Mendonça , Bello Gonzalo , Resende Paola Cristina 
Published: November 2021

SummaryThe rapid spread of the SARS-CoV-2 Variant of Concern (VOC) Gamma during late 2020 and early 2021 in Brazilian settings with high seroprevalence raised some concern about the potential role of reinfections in driving the epidemic. Very few cases of reinfection associated with the VOC Gamma, however, have been reported. Here we describe 25 cases of SARS-CoV-2 reinfection confirmed by real-time RT-PCR twice within months apart in Brazil. SARS-CoV-2 genomic analysis confirmed that individuals were primo-infected between March and December 2020 with distinct viral lineages, including B.1.1, B.1.1.28, B.1.1.33, B.1.195 and P.2, and then reinfected with the VOC Gamma between 3 to 12 months after primo-infection. The overall mean cycle threshold (Ct) value of the first (25.7) and second (24.5) episodes were roughly similar for the whole group and 14 individuals displayed mean Ct values < 25.0 at reinfection. Sera of 14 patients tested by plaque reduction neutralization test after reinfection displayed detectable neutralizing antibodies against Gamma and other SARS-CoV-2 variants (B.1.33, B.1.1.28 and Delta). All individuals have milder or no symptoms after reinfection and none required hospitalization. The present study demonstrates that the VOC Gamma was associated with reinfections during the second Brazilian epidemic wave in 2021 and raised concern about the potential infectiousness of reinfected subjects. Although individuals here analyzed failed to mount a long-term sterilizing immunity, they developed a high anti-Gamma neutralizing antibody response after reinfection that may provide some protection against severe disease.
Respiratory symptoms of Swiss people with Primary Ciliary Dyskinesia
Authors: Goutaki Myrofora , Hüsler Leonie , Lam Yin Ting , Koppe Helena M. , Jung Andreas , Lazor Romain , Müller Loretta ,   Swiss PCD research group, Pedersen Eva SL , Kuehni Claudia E. 
Published: November 2021

ABSTRACTBackgroundMostly derived from chart reviews, where symptoms are recorded in a nonstandardised manner, clinical data about primary ciliary dyskinesia (PCD) are inconsistent, which leads to missing and unreliable information. We assessed the prevalence and frequency of respiratory symptoms and studied differences by age and sex among an unselected population of Swiss people with PCD.MethodsWe sent a questionnaire that included items from the FOLLOW-PCD standardised questionnaire to all Swiss PCD registry participants.ResultsWe received questionnaires from 74 out of 86 (86%) invited persons or their caregivers (age range: 3–73 years; median age: 23), including 68% adults (≥18 years) and 51% females. Among participants, 70 (94%) reported chronic nasal symptoms, most frequently runny nose (65%), blocked nose (55%), or anosmia (38%). Ear pain and hearing problems were reported by 58% of the participants. Almost all (99%) reported cough and sputum production. The most common chronic cough complications were gastroesophageal reflux (n=11; 15%), vomiting (n=8; 11%), and urinary incontinence (n=6; 8%). Only 9 participants (12%) reported frequent wheeze, which occurred mainly during infection or exercise, while 49 persons (66%) reported shortness of breath; 9% even at rest or during daily activities. Older patients reported more frequent nasal symptoms and shortness of breath. We found no difference by sex or ultrastructural ciliary defect.ConclusionThis is the first study that describes patient-reported PCD symptoms. The consistent collection of standardised clinical data will allow us to better characterise the phenotypic variability of the disease and study disease course and prognosis.Take home messageDetailed information about patient-reported PCD symptoms will help characterise the phenotypic variability of the disease and could inform the development of individualised treatment strategies for patients.
Modelling the effect of the interaction between vaccination and non-pharmaceutical measures on COVID-19 incidence
Authors: Canga Atsegine , Bidegain Gorka 
Published: November 2021

AbstractSince December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly from Wuhan (China) across the globe, affecting more than 200 countries by mid-2021, with over 190 M reported cases and around 4 M fatalities. During the first year of the pandemic, affected countries implemented a variety of non-pharmaceutical interventions to control virus transmission. In December 2020, countries started administering several authorised vaccines under a limited supply scenario. In this context, the aim of this study was to develop a SEIR-type continuous-time deterministic disease model, to determine the impact of interaction between different vaccination scenarios and levels of protection measures on disease incidence. For this, the model incorporates (i) a protection measure including low (self-protection), medium (mobility limitation), high (closure of indoor facilities) and very high (lockdown) protection levels, (ii) quarantine for confirmed cases, and (iii) vaccination rate and efficacy of four type of vaccines (Pfizer, Moderna, Astra Zeneca or Janssen). The model was verified and evaluated using the response timeline and vaccination strategies and rates in the Basque Country (N. Spain). Once the model performance was validated, different initial phase (when 30% of the population is vaccinated) vaccination scenarios were simulated, including (i) a realistic vaccine limited supply scenario, and (ii) four potential full vaccine supply scenarios where a unique vaccine type is administered. Some differences in disease incidence were found between vaccination scenarios for low and medium-level protection measures. However, regardless of the administered vaccine, a high-level protection scenario is the most effective to control the virus transmission and disease mortality in the studied initial phase of vaccination. The results obtained here may vary in further studies since there may be some unpredictable factors/covariates. With this in mind, the model here could be easily applied to other regions or countries, modifying the strategies implemented and initial conditions.
Structural insights into the mechanism of nucleotide regulation of pancreatic KATP channel
Authors: Wang Mengmeng , Wu Jing-Xiang , Ding Dian , Duan Xinli , Ma Songling , Lai Lipeng , Chen Lei 
Published: November 2021

AbstractATP-sensitive potassium channels (KATP) are metabolic sensors that convert the intracellular ATP/ADP ratio to the excitability of cells. They are involved in many physiological processes and implicated in several human diseases. Here we present the cryo-EM structures of the pancreatic KATP channel in both the closed state and the pre-open state, resolved in the same sample. The nucleotides bind at the inhibitory sites of the Kir6.2 channel in the closed state but not in the pre-open state. Structural comparisons reveal the mechanism for ATP inhibition and Mg-ADP activation, two fundamental properties of KATP channels. Moreover, the structure also uncovers the activation mechanism of diazoxide-type KATP openers.
The effect of consumer resistance to innovation on innovation adoption: the moderating role of customer loyalty
Authors: Sun Yang , Ding Wenmei , Weng Chen , Cheah Isaac , Cai Helen Huifen 
Published: November 2021

PurposeThe purpose of the study is to construct a relationship model between the consumer resistance to innovation (CRI) and innovation adoption, and the study selected the customer loyalty as the moderating variable.Design/methodology/approachBased on questionnaire survey and regression model analysis, the study analyses the psychological processes and formation mechanisms that they either resist or adopt innovation by exploring users' attitudes towards smartphone application updates.FindingsThe results showed that innovation resistance negatively affected innovation adoption, and consumers are more likely to adopt innovations simply under the influence of customer loyalty. In addition, the moderating effect of customer loyalty is different in that how the three dimensions of innovation resistance influence innovation adoption. From the perspective of affective response, when consumers become emotionally disgusted with innovative products, loyalty can hardly change their minds. When consumers' resistance to innovation comes more from cognitive evaluation or functioning, loyalty is more likely to change their resistance.Originality/valueThe paper tests mechanism between customer resist the new product and new product adoption and the moderate effect of customer loyalty.
Profiling food festivals by type, name and descriptive content: a population level study
Authors: Kesgin Muhammet , Murthy Rajendran , Lagiewski Rick 
Published: November 2021

PurposeThis research aims to classify and describe food festivals and examine the patterns in food festival naming and festival descriptions in online media.Design/methodology/approachThis research represents the first population-level empirical examination of food festivals in the United States using a purpose-built dataset (N = 2,626). Methodology includes text mining to examine food festival communications.FindingsFood festival size varies across local and regional spheres within the country. Food festivals employ geographical (place-, destination-based) associations in their names. Food festivals' descriptions and online communications showcase a welcoming environment predominantly emphasizing family-oriented and live entertainment experiences. Food festivals across the country show common naming patterns based on the elements of longevity, recurrence, location name, brand name, geographic scope, theme, and occasion.Originality/valueThe study makes an original contribution to the theory and practice by identifying festival forms, styles, functions, and their diversity. A population level examination of food festivals does not currently exist. Therefore, this research will serve as a foundation for scholarly work in the future and as a benchmark for evaluating current and future research.
Characterization of the shopping preferences and needs of low-income consumers living in food deserts
Authors: Mogil Samantha , Hill Evanah , Quinlan Jennifer 
Published: November 2021

PurposeLack of access to supermarkets and fresh produce continues to be a problem for low income consumers in many countries. The purpose of this research was to identify the shopping preferences and needs of such consumers in the Eastern U.S. Additionally, the research sought to determine the interest and preferences of low income consumers in a mobile grocery intervention which would provide neighborhoods with a consistent, convenient shopping experience.Design/methodology/approachA mixed methods approach included conducting focus groups in low-income neighborhoods in Philadelphia, Pennsylvania, U.S.A. and a quantitative survey (n = 202) administered via Survey Monkey to low-income consumers. Thematic analysis was conducted on focus group data and surveys were administered and analyzed to assess applicability of themes identified to consumers over a larger geographic area.FindingsResults indicated that consumers in food desert neighborhoods reported an interest in purchasing a wide range of food staples, household goods, and personal items from any shopping intervention. Participants indicated a need for a more convenient overall shopping experience for a range of foods and goods in addition to fresh food choices. Findings indicate that mobile interventions to increase food access may benefit from expanding products available through the intervention beyond fresh produce and perishable goods.Originality/valueThis research explored purchasing preferences with low income consumers living in food deserts. It identifies products and goods they would prefer to see in an intervention to increase food access and is unique in that it explores the wants and preferences of consumers living in food deserts.
Children’s menus in shopping centre restaurants: a multicentric study
Authors: Viegas Cláudia , Lima João , Afonso Cláudia , Toth András Jozsef , Bálint Illés Csaba , Bittsánszky András , Šatalić Zvonimir , Vidaček Filipec Sanja , Fabijanic Valeria , Duran Samuel , Torres Jairo Alonso , Spinelli Monica , Matias Andrea , Souza Pinto Ana Maria , Rocha Ada 
Published: November 2021

PurposeThe aim of this study is to identify and characterize kids' menu offer in fast-food and traditional restaurants located in shopping centres in five different countries.Design/methodology/approachAn observational cross-sectional study is carried out, though a study was performed in all restaurants located in shopping centres from main cities, in five countries: Brazil, Chile, Croatia, Hungary and Portugal. A tool for assessing the quality of menus is used for the analysis (Kids Menu Healthy Score (KIMEHS)). Menu prices between countries were compared.FindingsA total of 192 kids' menus were collected, 44 in Portugal, 57 in Brazil, 66 in Chile, 15 in Hungary and 10 in Croatia. All the countries have average negative KIMEHS values for the menus, indicating that the offer is generally poor in terms of healthy options. The cost of children's menus in European countries is generally low. In Brazil, the price is significantly more expensive, which may limit the accessibility by social economically deprived populations. No significant differences were found in the average cost of meals from different restaurants typology. Traditional/Western restaurants present the highest price.Practical implicationsGlobally, kids' menus are composed by unhealthy food items, pointing to the need of improvements in food availability, aiming to promote healthy food habits among children.Originality/valueThis study presents innovative data on children's menus, allowing for characterization of meals offered to children and comparison between different countries.Key pointsKids’ menus are composed by unhealthy food items.Improvement of kids' menus quality will promote children food habits.Healthier out-of-home food consumption will contribute to public health.
Brain drain in microfinance institutions: the role of gender and organizational factors
Authors: Nourani Mohammad , Mia Md Aslam , Saifullah Md. Khaled , Ahmad Noor Hazlina 
Published: November 2021

Purpose
Uncontrollable brain drain (employees’ turnover) has been found to hamper humanitarian and sustainable objectives of socially oriented organizations. Hence, this study aims to explore the roles of gender and organizational-level factors on the rate of employees’ turnover in microfinance institutions (MFIs).

Design/methodology/approach
The study used an unbalanced panel data of 235 MFIs spanning the period 2010–2019. Based on the availability of the required data set on the World Bank catalogue (in collaboration with Microfinance Information Exchange-MIX Market), this study covers four South Asian countries, namely, Bangladesh, India, Pakistan and Sri Lanka. Then, the authors analyzed the data using the conventional panel data regression techniques (e.g. fixed effects model and random effects model).

Findings
The regression results revealed that women leaders (board members) could significantly reduce the employee turnover rate of MFIs. Although the efficiency wage hypothesis is supported in this study, it depends on the profit orientation of the MFIs. This study also confirmed that financial sustainability and donations have helped MFIs to reduce their employees’ turnover, which reiterates the image and brand value effect of MFIs. Moreover, the overall gender development and legal status (e.g. Bank and Non-Bank Financial Institutions) have also been found to have an effect on employees’ turnover based on the sub-sample analysis.

Originality/value
To the best of the authors’ knowledge, the study is among the first to investigate the impact of gender and institutional characteristics on employees’ turnover based on a large and recent panel dataset from selected South Asian countries.
Segmenting children’s active school travel behaviour: insights on caregivers’ perceived risks and social norms
Authors: Saleme Pamela , Pang Bo 
Published: November 2021

PurposeActive school travel (AST) programmes aim to change commuting behaviour to improve children's physical and mental health. However, very limited health education programmes for children use segmentation to create tailored solutions that understand the specific characteristics of each group of children and their caregivers in order to yield better results. The aim of this study is to use a statistical segmentation analysis (two-step cluster analysis) to gain insights on the examination of specific groups to design future health education interventions and campaigns that can improve children's health.Design/methodology/approachGuided by the Ecological and Cognitive Active Commuting (ECAC) framework, a market segmentation analysis was performed. An online survey was designed to collect data from caregivers of children between 5 and 12 years attending school and responsible for taking the child to and/or from school in Victoria and Queensland, Australia. Using 3,082 responses collected from Australian caregivers of primary school children, a two-step cluster analysis was performed.FindingsAnalysis revealed the most important variables for group formation were previous child walking behaviour, distance from school and caregiver income. Perceived risk of the physical environment was the most important psychographic segmentation variable for group formation, followed by social norms. Four distinct groups with different characteristics were identified from the analysis.Originality/valueThis is the first study that applies the ECAC framework to perform market segmentation in the AST context. Results revealed four market segments that demand different tailored solutions. Findings shed light on how to better design AST interventions and campaigns to promote children's health using segmentation techniques.
Women’s health concern in Jordan: knowledge, practice and barriers toward cervical cancer screening
Authors: Maabreh Roqia Saleem , Al-Husban Raya Yousef , Al-Akash Hekmat Yousef , Al-Shdayfat Noha 
Published: November 2021

PurposeCervical cancer (CC) is one of the most important health issues faced by women worldwide. The purpose of this study is to identify Jordanian women’s knowledge, barriers and measures pertaining to risk factors and screening choices of CC (Pap smear tests).Design/methodology/approachThis study applied a cross sectional design by collecting data from a convenient sample of 200 women between 20 and 70 years of age in health and public centers in Jordan. Data was then analyzed using the descriptive statistical tools of SPSS, version 21.FindingsThe findings revealed that 55.5% of the participants had no information about the Pap smear, and 75% did not know the risk factors. Moreover, 50% of the sample did not know where to take the test, and 50% reported a lack of encouragement from the husband to undertake the test. More than half of the participants (56.5%) expressed fear that cervical screening would be a painful examination even though they reported not having any previous experience with the test.Originality/valueBased on these findings, public education about CC screening is essential, including advertising and a campaign similar to the breast cancer awareness programs in Jordan, as a way of encouraging early screening to improve the health of women.
Corporate social responsibility disclosure and information asymmetry: does boardroom attributes matter?
Authors: Hamrouni Amal , Bouattour Mondher , Ben Farhat Toumi Nadia , Boussaada Rim 
Published: November 2021

PurposeThe current study aims to investigate the relation between corporate social responsibility (CSR) and information asymmetry, as well as the moderating effect of board characteristics (gender diversity, size and independence) on this relationship.Design/methodology/approachThis paper uses a panel data regression analysis with the system generalized method of moments (SGMM) estimator of nonfinancial French firms included in the SBF 120 index. The environmental and social disclosure scores are collected from the Bloomberg database, while financial data are collected from the FactSet database.FindingsThe empirical results demonstrate that environmental disclosure has a positive impact on the level of information asymmetry, while social disclosure has no effect on the information environment. Gender diversity and board independence negatively impact the opacity index, while board size has a positive effect. The presence of women in board composition has a substitution effect on the relationship between environmental disclosure and information asymmetry. There is no moderating effect of board size on the association between CSR disclosure and information asymmetry. However, the proportion of independent female directors and board independence operates as substitutes to social disclosure on reducing information asymmetry.Research limitations/implicationsAlthough the models include the most common control variables used in the literature, they omit some variables. Second, the results should be interpreted with caution and should not be generalized to the entire stock market since the sample is based on large French companies.Practical implicationsThe results of this study may be of interest to managers, investors and French market authorities since France is characterized by highly developed laws and reforms in the area of CSR. In addition, the paper leads to a better understanding of how women on the board, in particular, independent female directors, affect the relationship between CSR disclosure and information asymmetry. This could be of interest to French authorities, which has encouraged the appointment of women through the adoption of the Copé–Zimmermann law.Originality/valueFirst, to the best of the authors' knowledge, this is the first study to explore the moderating effect of board characteristics on the relationship between CSR and information asymmetry. Second, unlike previous studies using individual proxies to measure information asymmetry, the authors favor the opacity index of Andersonet al.(2009). They calculate this index by including a fifth individual measure, namely, share price volatility. The opacity index better describes the information environment of companies than individual measures since it reflects the perceptions of investors and analysts together.