bluuebunny/crossref_metadata_2025_split huggingface dataset:
Zinc as a complementary treatment for cancer patients: a systematic review
Authors: Hoppe C. , Kutschan S. , Dörfler J. , Büntzel J. , Büntzel J. , Huebner Jutta 
Published: January 2021

AbstractZinc is a trace element that plays an important role in the immune system and cell growth. The role of zinc in cancer treatment has been discussed for some time, however without reaching an evidenced-based consensus. Therefore, we aim to critically examine and review existing evidence on the role of zinc during cancer treatment. In January 2019, a systematic search was conducted searching five electronic databases (Embase, Cochrane, PsychINFO, CINAHL and PubMed) to find studies concerning the use, effectiveness and potential harm of zinc therapy on cancer patients. Out of initial 5244 search results, 19 publications concerning 23 studies with 1230 patients were included in this systematic review. The patients treated with zinc were mainly diagnosed with head and neck cancer and underwent chemo-, radio- or concurrent radio-chemotherapy. Interventions included the intake of different amounts of zinc supplements and oral zinc rinses. Outcomes (primary endpoints) investigated were mucositis, xerostomia, dysgeusia, pain, weight, dermatitis and oral intake of nutrients. Secondary endpoints were survival data, quality of life assessments and aspects of fatigue, immune responses and toxicities of zinc. The studies were of moderate quality reporting heterogeneous results. Studies have shown a positive impact on the mucositis after radiotherapy. No protection was seen against mucositis after chemotherapy. There was a trend to reduced loss of taste, less dry mouth and oral pain after zinc substitution. No impact was seen on weight, QoL measurements, fatigue, and survival. The risk of side effects from zinc appears to be relatively small. Zinc could be useful in the prevention of oral toxicities during irradiation. It does not help in chemotherapy-induced side effects.
Why the COVID-19 Pandemic Could Increase the Corporate Saving Trend in the Long Run
Authors: Demary Markus , Hasenclever Stefan , Hüther Michael 
Published: January 2021

AbstractGiven the global trend in corporate saving over the last decades, the COVID-19 crisis raises doubts about the persistence of companies’ saving behaviour due to the losses which have occurred in many companies caused by the isolation of households and by lockdowns. Before the pandemic, corporate net lending activities had been increasing for decades due to various factors ranging from the rise in uncertainty after the global financial crisis to the increased reliance on internal funding for research and development expenditures. In Germany, the rise in corporate saving was accompanied by an increase in equity capital and a reduction in the corporate sector’s reliance on bank loans. This article argues that the coronavirus crisis is most likely to interrupt the trend in corporate saving in the short run due to the decline in companies’ revenues. Nonetheless, similar to the pattern observed in the aftermath of the financial crisis, it seems reasonable to conjecture that the COVID-19 shock will strengthen corporate saving in the long run as companies may attempt to restore their liquidity and equity capital buffers to better prepare for future shocks. This will in turn create downward pressure on real interest rates and complicate the conduct of monetary policy.
Traffic congestion and economic context: changes of spatiotemporal patterns of traffic travel times during crisis and post-crisis periods
Authors: Moyano Amparo , Stępniak Marcin , Moya-Gómez Borja , García-Palomares Juan Carlos 
Published: January 2021

AbstractThis paper aims to evaluate the impacts of the economic context on traffic congestion and its consequential effects on private vehicle accessibility. We conduct a long-term analysis of spatiotemporal traffic congestion patterns in Madrid (Spain), comparing two urban realms: the 2008 economic crisis and the following post-crisis situation. We apply TomTom Speed Profiles data to assess daily variations in traffic congestion and their changes between both periods, and Twitter data to capture spatial patterns of the daily pulse of the city. Increased traffic, a by-product of economic recovery, resulted in higher congestion, particularly during peak hours. Nevertheless, these changes are spatially uneven. In the city core, an increase in congestion is relatively temporally homogeneous, while in the peripheral suburban zones, there has been only a marginal increase in travel times. On the other hand, in the urban outskirts, increased traffic congestion is more severe but visibly different between north and south. These differences have strong social connotations: over 40% of the population experienced a dramatic increase in travel times (more than 25%) during peak hours. Moreover, low-income groups are more likely to live in the more affected southern districts, suffering most the negative consequences of increased congestion.
The Austrian school of Madrid
Authors: Matarán López Cristóbal 
Published: January 2021

AbstractThis paper focuses on the current situation and the historical development of Austrian Economics in Madrid. We will analyse the formation of this School as the result of the thesis defended by Joaquín Reig Albiol in the late fifties and the current economic debate surrounding the fractional reserve and other complex issues. In this half-century tour, we will explore three different generations of Austrian economists in Spain, whilst demonstrating that a distinct branch of the Austrian School is today live and well in Madrid. Eventually, we will discover how the Spanish Austrian economists have applied praxeology to contemporary political and economic problems and conclude that a vigorous and growing economic school of thought exists in Madrid.
Wie normativ ist die Kommunikationswissenschaft?
Authors: Geise Stephanie , Klinger Ulrike , Magin Melanie , Müller Kathrin Friederike , Nitsch Cordula , Riesmeyer Claudia , Rothenberger Liane , Schumann Christina , Sehl Annika , Wallner Cornelia , Zillich Arne Freya 
Published: January 2021

ZusammenfassungKommunikationswissenschaftliche Forschung ist durch die strukturellen Rahmenbedingungen geprägt, unter denen sie entsteht – etwa durch das Wissenschaftssystem, die gesellschaftlichen Erwartungen an Wissenschaft und das Mediensystem des jeweiligen Landes. Die quantitative Inhaltsanalyse untersucht im Vergleich zwischen Deutschland und den USA, inwiefern sich solche Rahmenbedingungen auf die normativen Vorstellungen auswirken, die Autorinnen aus diesen Ländern in ihren Zeitschriftenaufsätzen zum Ausdruck bringen. Hierzu wenden wir ein dreistufiges Vorgehen zur Identifikation, Systematisierung und Kategorisierung von „Sollensvorstellungen“ an und schlagen damit erstmals ein methodisches Verfahren vor, mit dem sich die Normativität von Fachzeitschriftenaufsätzen messen lässt, ohne die zu erfassenden Werte und Normen vorab festzulegen. Indikator für die Normativität der Aufsätze sind die darin artikulierten Sollensvorstellungen und konkreten Handlungsempfehlungen, die sich an verschiedene Gruppen richten können. Die Befunde zeigen keinen Unterschied im Grad der Normativität, wohl aber in den Schwerpunkten, die dabei gesetzt werden: Sollensvorstellungen und Handlungsempfehlungen in den deutschen Aufsätzen konzentrieren sich stärker auf Medien und Journalismus als auf unmittelbare Forschungsgegenstände des Fachs. Die US-amerikanischen Aufsätze hingegen weisen mit Schwerpunkt auf einem gelungenen gesellschaftlichen Zusammenleben stärker über das Fach hinaus und appellieren häufiger an die Verantwortung individueller Akteurinnen. Die Ergebnisse machen deutlich, dass strukturelle Unterschiede – auch vermittelt über die Forschungsgegenstände – die normativen Vorstellungen prägen, die Wissenschaftlerinnen leiten und von ihnen geäußert werden. Damit ruft die Studie die normative Prägung der Kommunikationswissenschaft ins Bewusstsein und liefert neue Erkenntnisse über das Selbstverständnis des Fachs.
Entrepreneurial ecosystems in an interconnected world: emergence, governance and digitalization
Authors: Bouncken Ricarda B. , Kraus Sascha 
Published: January 2021

AbstractAchieving and sustaining growth depends on the effective work of multiple and interconnected actors—such as e.g. governments, the private sector, society, universities, entrepreneurs and many others—who build an ecosystem, i.e. a social and economic environment for innovative and entrepreneurial endeavors. The underlying idea is that firms do not just compete with each other through well-developed stand-alone strategies to achieve advantages over their rivals, uniquely relying on their own resources, knowledge, and capabilities, but rather base their business models on shared resources, network externalities, knowledge spill-overs, local endowments, and governmental support. This introductory article offers a wide array of topics, methods and fields of application within the field of entrepreneurial ecosystems as well as a theorizing about potential fruitful future areas of research within the field, concentrating on legitimation and identification processes in ecosystems, possibly culminating towards a meta-identity of the ecosystem.
Three Risks That Caution Against a Premature Implementation of Artificial Moral Agents for Practical and Economical Use
Authors: Herzog Christian 
Published: January 2021

AbstractIn the present article, I will advocate caution against developing artificial moral agents (AMAs) based on the notion that the utilization of preliminary forms of AMAs will potentially negatively feed back on the human social system and on human moral thought itself and its value—e.g., by reinforcing social inequalities, diminishing the breadth of employed ethical arguments and the value of character. While scientific investigations into AMAs pose no direct significant threat, I will argue against their premature utilization for practical and economical use. I will base my arguments on two thought experiments. The first thought experiment deals with the potential to generate a replica of an individual’s moral stances with the purpose to increase, what I term, ’moral efficiency’. Hence, as a first risk, an unregulated utilization of premature AMAs in a neoliberal capitalist system is likely to disadvantage those who cannot afford ’moral replicas’ and further reinforce social inequalities. The second thought experiment deals with the idea of a ’moral calculator’. As a second risk, I will argue that, even as a device equally accessible to all and aimed at augmenting human moral deliberation, ’moral calculators’ as preliminary forms of AMAs are likely to diminish the breadth and depth of concepts employed in moral arguments. Again, I base this claim on the idea that the current most dominant economic system rewards increases in productivity. However, increases in efficiency will mostly stem from relying on the outputs of ’moral calculators’ without further scrutiny. Premature AMAs will cover only a limited scope of moral argumentation and, hence, over-reliance on them will narrow human moral thought. In addition and as the third risk, I will argue that an increased disregard of the interior of a moral agent may ensue—a trend that can already be observed in the literature.
Health Benefits of Fermented Bamboo Shoots: The Twenty-First Century Green Gold of Northeast India
Authors: Behera Prapti , Balaji Seetharaman 
Published: January 2021

AbstractThe word “bamboo” reminds us of “a hollow stick,” but it is filled with a plethora of health benefits. The tribals of northeastern India ferment these beneficial bamboo shoots for the goodness of mankind. Fermentation is an important age-old biotechnological procedure used for the preservation of food products. Fermented bamboo shoots form the niche for many microorganisms, and this confers positive effects and advantages in many ways. These magical shoots have tremendous health benefits like anti-cancer, anti-oxidant, anti-aging, cardioprotective, weight loss, probiotics, to name a few. Apart from health benefits, fermented bamboo shoots form important functional foods and have industrial and economical values. Though these are commonly found and started in the tribal area, and local markets, today, they are valuable all around the world, as popular as gold. Hence, fermented bamboo shoots are referred as “green gold” of India. This review briefs about various health benefits, advantages, disadvantages, future scope, and finally the economic values of fermented bamboo shoots, the “green gold” of the twenty-first century.
Effects of a Trans-Galactooligosaccharide on Minerals Content of Common Carp (Cyprinus carpio L.) Tissues
Authors: Ziółkowska Ewa , Bogucka Joanna , Mazurkiewicz Jan , Rawski Mateusz , Różański Szymon , Stanek Magdalena 
Published: January 2021

AbstractCommon carp (Cyprinus carpio L.) is a dominant fish species in aquaculture, and as it is a stomachless species, absorption and digestion of nutrients take place in the intestine. The aim of the study was to evaluate the effects of a prebiotic on the content of selected minerals found in the meat, gills, and skeleton of common carp. The research applied trans-galactooligosaccharide (GOS) prebiotic produced by enzymatic transgalactosylation of milk lactose by whole cells of Bifidobacterium bifidum. The following diets have been applied: control diet without feed additives (C), diet 2 (B1) with 1% of GOS, and diet 3 (B2) with 2% of GOS. In the freeze-dried samples, concentrations of the analyzed metals were determined using atomic absorption spectroscopy (AAS). The content of phosphorus was determined using colorimetric method. The analyses confirmed that the highest level of Mg was detected in the skeleton of fish fed with 1% GOS (2.51 g kg−1) and was significantly higher compared the control treatment (2.11 g kg−1) (P < 0.05). Zn content in fish meat fed with 1% GOS (35.41 mg kg−1) was significantly higher (P < 0.05) than in the control group (24.59 mg kg−1). The tissue that accumulated the greatest amount of Zn was the gills. GOS had a positive effect on Fe accumulation in the meat, gills, and skeleton. It has been concluded that supplementation of feed with 2% GOS significantly influenced the positive correlations between Mg and P in the meat and skeleton, Fe–Ca correlation in gills, and Fe–Zn correlation in the skeleton.
Socioeconomic status and global physical self-concept of adolescents: a multilevel structural equation modeling approach
Authors: Vollmer Johannes , Lohmann Julia , Giess-Stüber Petra 
Published: January 2021

AbstractThe global physical self-concept (GPSC) is a central part of one’s self-definition in adolescence and plays an important role in adolescents’ physical and psychological health. Socioeconomic status (SES) can be assumed to have an impact on GPSC, but this relationship has received little attention thus far. We investigated, therefore, the direct and indirect relationships between SES factors, such as parental educational level, occupational status, and family income, and adolescents’ GPSC. A sample of 966 adolescents from 47 9th-grade classes was examined. Multilevel structural equation modeling was used for the analyses. The results revealed an indirect positive effect of parental educational level on adolescents’ global physical self-concept. The effect was completely mediated by parental occupational status, parental sport participation, adolescents’ social resources, and adolescents’ physical exercise and sport activity. The tested model explained 28% of the variance in adolescents’ global physical self-concept. Implications for the development of suitable interventions to improve the global physical self-concept of adolescents are derived.
Immune Cell Infiltration into the Brain After Ischemic Stroke in Humans Compared to Mice and Rats: a Systematic Review and Meta-Analysis
Authors: Beuker Carolin , Strecker Jan-Kolja , Rawal Rajesh , Schmidt-Pogoda Antje , Ruck Tobias , Wiendl Heinz , Klotz Luisa , Schäbitz Wolf-Rüdiger , Sommer Clemens J. , Minnerup Heike , Meuth Sven G. , Minnerup Jens 
Published: January 2021

AbstractAlthough several studies have suggested that anti-inflammatory strategies reduce secondary infarct growth in animal stroke models, clinical studies have not yet demonstrated a clear benefit of immune modulation in patients. Potential reasons include systematic differences of post-ischemic neuroinflammation between humans and rodents. We here performed a systematic review and meta-analysis to summarize and compare the spatial and temporal distribution of immune cell infiltration in human and rodent stroke. Data on spatiotemporal distribution of immune cells (T cells, macrophages, and neutrophils) and infarct volume were extracted. Data from all rodent studies were pooled by means of a random-effect meta-analysis. Overall, 20 human and 188 rodent stroke studies were included in our analyses. In both patients and rodents, the infiltration of macrophages and neutrophils preceded the lymphocytic influx. Macrophages and neutrophils were the predominant immune cells within 72 h after infarction. Although highly heterogeneously across studies, the temporal profile of the poststroke immune response was comparable between patients and rodents. In rodent stroke, the extent of the immune cell infiltration depended on the duration and location of vessel occlusion and on the species. The density of infiltrating immune cells correlated with the infarct volume. In summary, we provide the first systematic analysis and comparison of human and rodent post-ischemic neuroinflammation. Our data suggest that the inflammatory response in rodent stroke models is comparable to that in patients with stroke. However, the overall heterogeneity of the post-ischemic immune response might contribute to the translational failure in stroke research.
Macro and micro grouting process and the influence mechanism of cracks in soft coal seam
Authors: Yu Hui , Jia Housheng , Liu Shaowei , Liu Zhihe , Li Baoyu 
Published: January 2021

AbstractGrouting is an important method to reinforce soft coal roadway, and the presence of primary cracks in the coal body has an important influence on the grouting effect. With the discrete element simulation method, the grouting process of the soft coal seam was simulated. The mechanism of primary cracks on grouting was revealed, while the influence of fracture characteristics and grouting pressure on the grouting effect was analyzed. The results demonstrated that grouting in the soft coal seam involves the stages of seepage, rapid splitting, slow splitting, and stability. Due to the presence of primary cracks, the grouting diffusion radius increased significantly. Under the slurry pressure, the tensile stress concentration was formed at the crack tip, and the slurry split the coal once the splitting pressure was reached. In addition, the distribution characteristics of fractures are found to have a great influence on the grouting effect. It is observed that smaller fracture spacing is associated with a larger slurry diffusion radius and thus easier penetration of the primary crack tips. The fracture angle affects the direction of fracture propagation. The secondary fracture formed by splitting is a tensile fracture, which is more likely to extend along the direction parallel to the maximum principal stress. Overall, these simulation results have guiding significance for the setting of reasonable spacing of grouting holes in the practice of grouting engineering.
Structural Correspondence Between Organizational Theories
Authors: Aksom Herman , Firsova Svitlana 
Published: January 2021

AbstractOrganizational research constitutes a differentiated, complex and fragmented field with multiple contradicting and incommensurable theories that make fundamentally different claims about the social and organizational reality. In contrast to natural sciences, the progress in this field can’t be attributed to the principle of truthlikeness where theories compete against each other and only best theories survive and prove they are closer to the truth and thus demonstrate scientific knowledge accumulation. We defend the structural realist view on the nature of organizational theories in order to demonstrate that despite the multiplicity of isolated and competing explanations of organization-environment relations these theories are still logically compatible and mutually consistent which, in turn, assures theoretical progress in the field. Although postulating different and incompatible ontologies, three most successful organization-environments theories, namely, contingency theory, new institutionalism and population ecology share the same explanations of the relations between organizations and environments at the structural level. Without this principle one would say that what occurs in the field of organization theory is a change rather than a progress.
Cultural Safety and Child Protection Responses in Hospitals: a Scoping Review
Authors: Flemington Tara , Lock Mark , Shipp Joanne , Hartz Donna , Lonne Bob , Fraser Jennifer Anne 
Published: January 2021

AbstractThe objective of this scoping review was to map the current practice and best evidence for embedding cultural safety in child protection responses for Aboriginal families in hospitals. Electronic databases were searched systematically and the reference lists examined. Efforts to reduce the risk of bias were made including using an inductive approach. Eight research papers were included following the exclusion of 25 papers for the final analysis. Three main themes in relation to what is necessary to embed cultural safety for Aboriginal families when child protection responses are raised in hospital were found. These were (a) relationships, (b) organisational processes and (c) culture. The analysis underscores the need for development of child protection strategies that focus on cultural safety rather than cultural competence alone. This provides some direction for policy and practice development in this field, and has also highlighted the deficiencies in evidence and urgent need for further research.
A Branch-and-Cut-and-Price Algorithm for the Electric Vehicle Routing Problem with Multiple Technologies
Authors: Ceselli Alberto , Felipe Ángel , Ortuño M. Teresa , Righini Giovanni , Tirado Gregorio 
Published: January 2021

AbstractWe provide an exact optimization algorithm for the electric vehicle routing problem with multiple recharge technologies. Our branch-and-cut-and-price algorithm relies upon a path-based formulation, where each column in the master problem represents a sequence of customer visits between two recharge stations instead of a whole route. This allows for massive decomposition, and parallel implementation of the pricing phase, exploiting the large number of independent pricing sub-problems. The algorithm could solve instances with up to thirty customers, nine recharge stations, five vehicles and three technologies to proven optimality. Near-optimal heuristic solutions were obtained with a general-purpose MIP solver from the columns generated at the root node.