bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multitarget Stool RNA Test for Noninvasive Detection of Colorectal Neoplasia in a Multicenter, Prospective, and Retrospective Cohort
Authors: Barnell Erica K. , Kang Yiming , Barnell Andrew R. , Kruse Kimberly R. , Fiske Jared , Pittz Zachary R. , Khan Adnan R. , Huebner Thomas A. , Holmes Faith L. , Griffith Malachi , Griffith Obi L. , Chaudhuri Aadel A. , Wurtzler Elizabeth M. 
Published: May 2021

INTRODUCTION:
Effective colorectal cancer (CRC) prevention and screening requires sensitive detection of all advanced neoplasias (CRC and advanced adenomas [AA]). However, existing noninvasive screening approaches cannot accurately detect adenomas with high sensitivity.

METHODS:
Here, we describe a multifactor assay (RNA-FIT test) that combines 8 stool-derived eukaryotic RNA biomarkers, patient demographic information (smoking status), and a fecal immunochemical test (FIT) to sensitively detect advanced colorectal neoplasias and other non-advanced adenomas in a 1,305-patient, average-risk, prospective cohort. This cohort was supplemented with a 22-patient retrospective cohort consisting of stool samples obtained from patients diagnosed with AA or CRC before treatment or resection. Participants within these cohorts were evaluated with the RNA-FIT assay and an optical colonoscopy. RNA-FIT test results were compared with colonoscopy findings.

RESULTS:
Model performance was assessed through 5-fold internal cross-validation of the training set (n = 939) and by using the model on a hold out testing set (n = 388). When used on the hold out testing set, the RNA-FIT test attained a 95% sensitivity for CRC (n = 22), 62% sensitivity for AA (n = 52), 25% sensitivity for other non-AA (n = 139), 80% specificity for hyperplastic polyps (n = 74), and 85% specificity for no findings on a colonoscopy (n = 101).

DISCUSSION:
The RNA-FIT assay demonstrated clinically relevant detection of all grades of colorectal neoplasia, including carcinomas, AAs, and ONAs. This assay could represent a noninvasive option to screen for both CRC and precancerous adenomas.
Miss Tacuarembó: The Transformation of Gender and Genre in Argentinian Musicals
Authors: Ponti Martín 
Published: May 2021

AbstractThis article examines Natalia Oreiro, a film and television star who has contributed to representations of on-screen queer subjectivities in Latin America. I examine her film Miss Tacuarembó (Sastre 2010) as a musical that resignifies heteronormative notions of gender commonly found in popular family film genres. I consider the film’s layered intertexts such as choreography, pop songs, and telenovelas, as well as the role of Oreiro in resignifying those intertextual codes as signs of queerness. This article thus reveals the ways in which intertexts disrupt this formulaic family and young adult film.
DETEKSI BUKTI DIGITAL ONLINE GAMBLING MENGGUNAKAN LIVE FORENSIK PADA SMARTPHONE BERBASIS ANDROID
Authors: Sah Andrian , Riadi Imam , Prayudi Yudi 
Published: May 2021

Internet as media to do political movement. Since that, the Indonesian people understand internet-based activities until this current progress. Use of internet in Indonesia most frequently utilize units to access internet, namely, handphone, laptop/notebook, Personal Computer (PC), and tablet. Media used to access internet include mobile (47.6%), computer (1.7%) and both (50.7%). Use of internet increases so that criminal action rate is higher; for example, online gambling. In general, online gambling is done using smartphone. However, today smartphone can load more than one type of online gambling. So speedy progress of online gambling must contain criminal action. Criminal action is taken by involving smartphone having online gambling with impact on challenge to prove digital evidences and analyze it. Online gambling is a crime or criminal action being social problems resulting in negative impacts such as morale and mental disorders in society, especially young generation. Questions asked in this study are how to find characteristic of online gambling and digital evidences available to smartphone. This study focuses on characteristic and digital evidences in smartphone based on facts found in thing of evidence. Based on results of study, we found some types of online gambling in smartphone. Characteristic and digital evidences found in smartphone were found by using forensic media, namely, XRY. Forensic media of XRY were used to find thing of digital evidence in smartphone, such as, ID, Password and transaction of online gambling via social applications.
KECANDUAN GADGET DALAM INTERAKSI SOSIAL PADA REMAJA SMA DAERAH BANTUL DAN SLEMAN
Authors: Huda Husna nuur 
Published: May 2021

Kecanduan gadget adalah salah satu aspek masalah penggunaan smartphone yaitu lama waktu pemakaian, tentu saja dampak yang ditimbulkan dari kecanduan teknologi ini memilki sisi positif dan negatif, namun disini penulis tidak membahas dampak dari gadget tersebut karna sudah banyak diteliti. Penelitian ini bertujuan untuk mengemukakan argumen dari beberapa partisispan yang bisa dikatakan kecanduan gadget sehingga dapat diketahui apa penyebab remaja kecanduan gadget, dan kita bisa melihat kecenderuangan remaja terhadap gadget lebih digunakan kearah mana? Bisa jadi sebagai hiburan, informasi, maupun untuk menanggulangi kesulitan. Penelitian ini merupakan penelitian lapangan (field research) dengan metode kualitatif. Pendekatan penelitian ini menggunakan fenomenologi dengan mendeskripsikan pengalaman kehidupan manusia tentang sesuatu fenomena tertentu seperti yang dijelaskan oleh partisipan. Teori yang akan dipakai diantaranya adalah Teori Weber memperkenalkan "makna" sebagai konsep teori tindakan dasar dan menggunakannya untuk membedakan tindakan dari perilaku yang dapat diamati: "Perilaku manusia, apakah eksternal atau internal, aktivitas, tidak berbuat atau pasif mengikuti sesuatu yang terjadi, akan disebut dengan "tindakan" jika dan selama aktor melekatkan makna subjektif kepada perilaku tersebut. Dan teori Interaksionalisme simbolik Harbert Blumer, proses-proses interaksi yaitu tindakan sosial yang dicirikan oleh orientasi timbal-balik langsung dan penyelidikan-penyelidikan terhadap proses-proses tersebut didasarkan secara khusus kepada konsep interaksi yang menitikberatkan ciri-ciri simbolik tindakan sosial. Dengan demikian peneliti dapat mengetahui argumen partisipan sehingga melatar belakangi mereka kecanduan gadget, dan dapat dilihat bagaimana interaksi sosial mereka dilihat dari syarat-syarat terjadinya interaksi sosial. Kata kunci: kecanduan teknologi, interaksi sosial.
Bangkolo: Aplikasi Vulnerability Identification Berbasis Hybrid Apps
Authors: Hariyadi Dedy , Fazlurrahman Fazlurrahman , Wijayanto Hendro 
Published: May 2021

Keamanan merupakan hal penting dalam sistem maupun jaringan dalam melindungi data informasi. Tingginya tingkat laporang celah keamanan dari Edgescan menunjukkan masih minimnya pengembang sistem dan jaringan dalam hal menutamakan keamanan. Information System Security Assesment Framework (ISSAF) merupakan metodologi penetration testing yang dikembangkan oleh Open Information Systems Security Group. Dalam framework tersebut terdiri dari tiga fase, yaitu Planing and Preparation, Assessment dan Reporting, Clean-up and Destroy Astefacts. Dalam melakukan Vulnerabilities Identification diperlukan tools untuk mengetahui potensi celah keamanan dalam bentuk laporan. Ini sangat diperlukan untuk mempermudah analisis, penggunaan dan meminimalisir biaya pentesting. Selama ini tools pentesting kebanyakan masih menggunakan model Command Line Interface (CLI) sehingga sulit digunakan oleh orang awam. Sehingga diperlukan tools berbasis Graphic User Interface (GUI). Dengan pendekatan Hybrid Apps dapat dikembangkan aplikasi pentesting berbasis Graphic User Interface yang memanfaatkan kelebihan teknologi native dan web. Bangkolo merupakan aplikasi untuk pentesting yang dikembangkan dari framework ISSAF dan pendekatan Hybrid Apps.
Penerapan Fungsi Green dari Persamaan Poisson pada Elektrostatika
Authors: Khairi Fathul , Malahayati  
Published: May 2021

The Dirac delta function is a function that mathematically does not meet the criteria as a function, this is because the function has an infinite value at a point. However, in physics the Dirac Delta function is an important construction, one of which is in constructing the Green function. This research constructs the Green function by utilizing the Dirac Delta function and Green identity. Furthermore, the construction is directed at the Green function of the Poisson's equation which is equipped with the Dirichlet boundary condition. After the form of the Green function solution from the Poisson's equation is obtained, the Green function is determined by means of the expansion of the eigen functions in the Poisson's equation. These results are used to analyze the application of the Poisson equation in electrostatic.
A novel methodology for power loss allocation of both passive and active power distribution systems
Authors: Hota Ambika Prasad , Mishra Sivkumar , Mishra Debani Prasad , Salkuti Surender Reddy 
Published: May 2021

Abstract
This paper presents a new active power loss allocation (LA) scheme for fair allocation of losses among the end-user with due consideration to deregulation in power supply. In this deregulated environment, the developed technique assigns losses judiciously because it has simplified the difficulties lying with the division of cross-term power loss equation analytically without any assumptions and approximations. Further, it establishes a direct relationship between two end-voltages of a branch and its subsequent load currents, in terms of node-injected complex powers. This LA scheme assigns losses to the network participants with due consideration to their demands, power factors, and geographical locations in the network. Again, the strategy followed for remuneration of distributed generators (DGs) awards all benefits of network loss reduction (NLR) to the DG owners in terms of incentives/penalties after analyzing their actual impact towards system loss reduction. The effectiveness of the proposed method is not only investigated at different load levels but also with various types of DG power injection using a 33-bus radial distribution network (RDN) with/without DGs. The comparison results obtained signify the novelty of the present technique in contrast to other discussed established methods.
Revisión teórico-científica del marco conceptual de la emoción y el sentimiento y su aplicación al neuromarketing
Authors: Núñez-Cansado Marian , López López Aurora , Vela Delfa Cristina 
Published: May 2021

En primera instancia, este artículo aborda una revisión bibliográfica diacrónica de las principales aportaciones teóricas relativas a la delimitación del marco conceptual de la emoción y el sentimiento, para plantear, finalmente, una reflexión acerca de su aplicación en el ámbito de la investigación en neuromarketing. En los últimos años, los programas de investigación científica han optado, en mayor medida, por desmarcarse del que ha sido durante mucho tiempo el paradigma dominante en las teorías de la emoción -que unificaba el tratamiento de las nociones de emoción y sentimiento-, para inclinarse por definiciones capaces de significar las diferencias existentes entre ambos conceptos, desde una óptica multifactorial y diferencial. Por su parte, el análisis de la literatura científica sobre neuromarketing nos revela que, en la práctica, ambos términos se confunden. Se incurre, de este modo, en un neurocentrismo que ignora el papel de los sentimientos en la toma de decisión. Ciertamente, una gran mayoría de estudios, procedentes de la praxis en este campo, centran sus resultados en aspectos meramente fisiológicos-biológicos, y dejan a un lado datos relevantes relativos a los procesos cognitivos asociados a aspectos culturales, sociales y propios de los estilos cognitivos del sujeto; circunstancia que puede restar validez al constructo teórico y limitar bien la capacidad predictiva o la validez concurrente en el diseño de estas investigaciones.Por todo esto, con la revisión bibliográfica propuesta se aportará luz sobre la problemática científica existente en torno al manejo de las nociones de emoción y sentimiento, lo que contribuirá, a su vez, a la adopción de una perspectiva más crítica y acertada acerca de cuáles deberían ser realmente sus usos y aplicaciones en el ámbito de la investigación en general, y del neuromarketing en particular. En este sentido, es importante superar algunas de las actuales limitaciones concernientes a las metodologías mixtas e integradas con las que se mide y observa la actividad cerebral, y para ello las aclaraciones teórico-científicas que resultan de este estudio serán claves y dilucidadoras.
Use of Tensiomyography in Evaluating Sex-Based Differences in Resistance-Trained Individuals After Plyometric and Isometric Midthigh Pull Postactivation Potentiation Protocols
Authors: Herring Chad H. , Goldstein Erica R. , Fukuda David H. 
Published: May 2021

Abstract
Herring, CH, Goldstein, ER, and Fukuda, DH. Use of tensiomyography in evaluating sex-based differences in resistance-trained individuals after plyometric and isometric midthigh pull postactivation potentiation protocols. J Strength Cond Res 35(6): 1527–1534, 2021—The purposes of this study were to determine if there are sex-based differences in muscular contractile properties as measured by tensiomyography (TMG) and to determine if plyometrics or the isometric midthigh pull are effective methods of eliciting postactivation potentiation (PAP). Thirty strong, resistance-trained men (n = 15) and women (n = 15) underwent 3 testing days consisting of a PAP or control protocol, and pre-TMG and post-TMG and performance testing. Contractile properties from TMG were assessed in the gastrocnemius medial head (GMH), gluteus maximus (GM), rectus femoris (RF), and biceps femoris (BF). Performance testing included countermovement jumps (CMJs) and 30-m sprints. A time × sex interaction was found for GM delay time with women primarily influencing changes (mean difference = 2.74 ms) rather than men (mean difference = 1.32 ms). Main effects for time revealed an increase in GMH velocity of contraction (+0.004 mm·ms−1) and reductions in GM contraction time (−2.85 ms), GM delay time (−2.03 ms), RF delay time (−0.65 ms), CMJs (−2.74 cm), and 30-m time (0.05 seconds). Main effects for sex revealed greater values in women for GM contraction time (+15.50 ms), GM delay time (+6.65 ms), RF delay time (+2.26 ms), BF contraction time (+8.44 ms), BF delay time (+4.07 ms), BF maximal displacement (+2.27 mm), and 30-m time (+0.67 seconds), and lower values in women for GM velocity of contraction (−0.039 mm·ms−1) and CMJs (−13.46 cm).These findings may help practitioners optimize performance through enhanced assessments for injury risk, targeting specific muscles for training, and by selecting proper CAs and rest periods when using PAP.
Effects of Plyometric Jump Training on Electromyographic Activity and Its Relationship to Strength and Jump Performance in Healthy Trained and Untrained Populations: A Systematic Review of Randomized Controlled Trials
Authors: Ramirez-Campillo Rodrigo , Garcia-Pinillos Felipe , Chaabene Helmi , Moran Jason , Behm David G. , Granacher Urs 
Published: May 2021

Abstract
Ramirez-Campillo, R, Garcia-Pinillos, F, Chaabene, H, Moran, J, Behm, DG, and Granacher, U. Effects of plyometric jump training on electromyographic activity and its relationship to strength and jump performance in healthy trained and untrained populations: a systematic review of randomized controlled trials. J Strength Cond Res 35(7): 2053–2065, 2021—This systematic review analyzed the effects of plyometric jump training (PJT) on muscle activation assessed with surface electromyography during the performance of strength and jumping tasks in healthy populations across the lifespan. A systematic literature search was conducted in the electronic databases PubMed/MEDLINE, Web of Science, and SCOPUS. Only randomized controlled studies were eligible to be included in this study. Our search identified 17 studies comprising 23 experimental groups and 266 subjects aged 13–73 years, which were eligible for inclusion. The included studies achieved a median Physiotherapy Evidence Database score of 6. No injuries were reported among the included studies. Significant PJT-related improvements were reported in 7 of 10 studies and in 6 of 10 studies for measures of muscle activation during the performance of strength and jumping tasks, respectively. Moreover, a secondary correlational analysis showed significant positive relationships (r = 0.86; p = 0.012; r
2 = 0.74) between changes in muscle activation and changes in jump performance. However, from the total number (n = 287) of muscle activation response variables analyzed for strength and jumping tasks, ∼80% (n = 226) were reported as nonsignificant when compared with a control condition. In conclusion, PJT may improve muscle activation during the performance of strength and jumping tasks. However, conflicting results were observed probably arising from (a) studies that incorporated a large number of outcomes with reduced sensitivity to PJT, (b) methodological limitations associated to muscle activation measurement during strength and jumping tasks, and (c) limitations associated with PJT prescription. Future studies in this field should strive to solve these methodological shortcomings.
Analisis Pengaruh Koefisien Watermarking pada Citra RGB dengan Menggunakan Perbandingan DCT dan DWT
Authors: Masykuroh Kholidiyah 
Published: May 2021

Perkembangan internet yang semakin pesat dan kemudahan akses informasi digital menjadi peluang terjadinya cybercrime. Teknik pengamanan diperlukan pada informasi yang akan dikirimkan melalui media transmisi baik wireless maupun wired. Melalui penerapan watermarking diharapkan informasi terjaga dari serangan, penyisipan, penghapusan data, dan penggantian data. Penelitian ini membahas perbandingan metode watermarking menggunakan Discrete Cosine Transform (DCT) dan Discrete Wavelet Transform (DWT) pada citra berwarna. Means Square Error (MSE) dan Peak Signal to Noise Ratio (PSNR) merupakan parameter uji untuk mengukur rasio perbandingan citra asli dan citra watermarking. Hasil pengujian menunjukkan bahwa perbedaan jenis transformasi yang digunakan mempengaruhi nilai SNR citra RGB. Citra RGB dengan menggunakan DCT memiliki nilai SNR yang lebih tinggi dibandingkan dengan DWT yang ditunjukkan dengan nilai SNR citra Peppers 30 dB. Nilai koefisien yang diberikan pada citra yang disisipkan bervariasi mulai dari 5, 10, dan 50. Nilai ini mempengaruhi nilai SNR citra RGB dengan transformasi DCT. Along with the rapid development of the internet and the ease of access to digital information, cybercrime has a chance to occur. Security techniques are needed for information to be transmitted via transmission media, either wireless or wired. The application of watermarking has an opportunity to protect the information from attacks, insertion, deletion, and data replacement. This research discusses the comparison of watermarking methods using Discrete Cosine Transform (DCT) and Discrete Wavelet Transform (DWT) on color images. Means Square Error (MSE) and Peak Signal to Noise Ratio (PSNR) are a method to test parameters for measure the original image's ratio to the watermark image. The test results showed that the different types of transformations affect the SNR value of the RGB image. RGB image using DCT has a higher SNR value than DWT, which is indicated by the SNR value of Peppers image 30 dB. The coefficient value given to the inserted image varies from 5, 10, and 50. This value affects the SNR value of RGB images with DCT transformation.
Occurrence and Source Apportionment of Polycyclic Aromatic Hydrocarbons (PAHs) in Green Mussel (Perna viridis) from Cilincing Waters of Jakarta Bay, Indonesia
Authors: Yogaswara Deny , Partono Tri , Satya Awalina 
Published: May 2021

Green mussels (Perna viridis) as sedentary organisms have been adopted as bioindicators in the marine environment for many decades. They have been potentially affected by anthropogenic activity and organic contaminants such as polycyclic aromatic hydrocarbons (PAHs) in an aquatic environment. This study aims to determine concentration, distribution and potential sources of PAHs in green mussel biomass obtained from Cilincing waters, Jakarta Bay. Fresh green mussels were collected from aquaculture facilities at Cilincing waters of Jakarta Bay with various size categories of shell length and were extracted with solvent n-hexane-dichloromethane mixture using Soxhlet method. The concentrate of sample extract was purified using silica gel/sodium sulfate anhydrous with n-pentene-DCM effluent in fractionation. Finally, the purified sample was injected into the GC-MS instrument. The result showed that the highest concentration of total PAH (TPAH) was 126.47 ng.g-1 wet weight (ww), founded in the guts from the biggest group of green mussel (length of 6.00 to 7.99 cm), and 3-aromatic rings were predominantly detected in all group sizes of green mussel. The result of the LMW/ HMW and diagnostic binary ratio indicated that PAH contamination is caused by a mixed source of petrogenic and pyrogenic processes. It may be due to the presence of oil spilled and petroleum waste from shipyard and cargo activities and atmospheric deposition. Based on excess cancer risk (ECR) value and the concentration level of PAH carcinogenic according to National Agency of Drug and Food Control (BPOM) regulation, PAH level in green mussels are acceptable and minor negative impact due to typical human consumption. Nevertheless, it needs to be circumspect to exploiting green mussels as seafood resources for daily consumption due to the carcinogenic content.
Bioactive Compounds, Cosmeceutical And Nutraceutical Applications of Green Seaweed Species (Chlorophyta)
Authors: Taher, Ph.D Prof. Muhammad , Ruslan Fatin Syazwani , Susanti Deny , Mohammad Noor Normawaty , Aminudin Nurul Iman 
Published: May 2021

Seaweeds are valuable marine plants that have garnered much attention from the public due to their high bioactive, nutrients and minerals content. Seaweeds have been used in multiple applications, including in cosmeceutical, nutraceutical and pharmaceutical industries. Nevertheless, this review will focus on the bioactive compounds of Chlorophyta and their potential application in nutraceutical and cosmeceutical industries. Chlorophyta are believed to possess a significant amount of nutrients and minerals, sufficient to meet the daily requirements of nutrients and minerals in the human body. Considering the nutritional aspect, deficiency in nutrients may lead to severe ailments, including heart disease, neurological disorder and cancer. The main compounds studied in this review are polysaccharides, proteins, amino acids, lipids, fatty acids, pigments, minerals, vitamins and secondary metabolites. Among all, polysaccharides are the most exploited compounds and used in many advanced applications in the nutraceutical and cosmeceutical industries. This review also offers insights into the beneficial biological properties of Chlorophyta, highlighting their potential in cosmeceutical and nutraceutical applications. Further research is required to highlight the Chlorophyta sp. aquaculture, its extraction method, and the most targeted bioactive compounds from the species. Therefore, the challenge is to increase public awareness of the promising application of this species in the nutraceutical and cosmeceutical industries.