bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kupu-Kupu Sebagai Daya Tarik Ekowisata Di Kawasan Pariwisata Lebih, Gianyar, Bali
Authors: Dalem Anak Agung Gde Raka 
Published: April 2021

Penelitian tentang kupu-kupu sebagai daya tarik ekowisata di kawasan pariwisata Lebih, Gianyar dilaksanakan pada tahun 2019. Tujuan penelitian ini adalah untuk mengetahui jenis-jenis kupu-kupu yang ditemukan di kawasan tersebut serta mengetahui potensinya sebagai daya tarik ekowisata. Sampel kupu-kupu diambil melalui eksplorasi lokasi-lokasi penelitian, serta data lain diambil melalui wawancara. Kupu-kupu yang ditemukan di lokasi ini diidentifikasi kemudian dicatat. Potensi kupu-kupu sebagai daya tarik ekowisata dianalisis berdasarkan persepsi wisatawan. Lokasi dimana kupu-kupu telah dipakai sebagai daya tarik ekowisata, serta bagaimana membuat paket ekowisata berbasis kupu-kupu (jika ada) dilaporkan. Hasil studi ini menunjukkan bahwa ada 30 species kupu-kupu teridentifikasi di Kawasan Pariwisata Lebih. Berdasarkan hasil observasi serta wawancara dapat disimpulkan, bahwa ekowisata berbasis kupu-kupu atau produk ekowisata berbasis kupu-kupu sudah ada satu buah di Kawasan Pariwisata Lebih. Kawasan Pariwisata Lebih memiliki potensi untuk mengembangkan ekowisata berbasis kupu-kupu. Potensi ini dapat dilihat dari adanya kupu-kupu beragam, 30 jenis sebagai atraksi ekowisata. Potensi ini dapat ditingkatkan dengan keberadaan atraksi lainnya termasuk diantaranya keberadaan atraksi budaya dan atraksi buatan. Dari segi aksesibilitas: Kawasan Pariwisata Lebih termasuk relatif mudah diakses, khususnya oleh fasilitas transport yang dikelola berbasis online. Keberadaan fasilitas pariwisata di kawasan Lebih telah meningkat. Dukungan untuk pengembangan Kawasan Pariwisata Lebih telah diberikan oleh pemerintah. Setelah menetapkan sembilan desa serta beberapa desa di sekitarnya sebagai kawasan pariwisata, pemerintah serta pihak-pihak lainnya telah mengembangkan fasilitas dan menyelenggarakan even-even pariwisata pada kawasan ini.

Kata Kunci— Bali, ekowisata, Kawasan Pariwisata Lebih, kupu-kupu, potensi ekowisata
3. Ottawa through the Eyes of Refugee Children
Authors: Berti Rosalynn 
Published: April 2021

The objective of this research was to expand our understanding of the lived experiences of refugee children arriving in Canada. For this study, I collected drawings from thirteen recently arrived refugee children living in a transitional house in downtown Ottawa, Ontario. The children were prompted to draw a picture of their experience of arriving in Canada. Nine of the thirteen drawings portrayed a narrative of journey through the drawing of flags and various forms of transportation. Five of the children included a drawing of themselves, their facial expressions conveying how they felt about arriving in Canada. Six of the drawings portrayed positive emotions, the children expressing thankfulness or eagerness to be in Canada. Four of the drawings did not present a clearly distinguishable tone, suggesting neutrality or avoidance of the task. Three of the drawings portrayed negative emotions, including fear and grief. These drawings demonstrate that the experience of arriving in Canada is complex, not easily simplified to broad generalizations. The participants told unique stories and expressed an array of emotions ranging from excitement to grief, justifying an approach focused on the individual lived experiences. This research project provided space for thirteen children to tell their stories, stepping out from behind the veil of statistics-directed, adult-directed, or outsider-directed narratives and personalizing the refugee resettlement process.
5. The Effect of Climate Variability on Lake Water Balances and Water Quality in the Apex River Watershed, Baffin Island, Nunavut
Authors: Boomer Hannah 
Published: April 2021

Iqaluit, Nunavut is currently facing a water shortage as its population rises, and its drinking water reservoir, Lake Geraldine, is increasingly insufficient. The City of Iqaluit is currently looking into alternative sources of drinking water to supplement this reservoir. This study investigates the effects of inter-annual climate variability on the water chemistry of twenty Arctic lakes in a continuous permafrost region, and the potential implications of these changes on drinking water availability. The twenty lakes are located in the Niaqunguk (Apex) river watershed, Baffin Island, Nunavut (which is adjacent to the Lake Geraldine watershed at Iqaluit) were sampled annually during late July between 2014-2017. Ion concentrations and stable isotopes were measured for each lake annually throughout the study period to compare variability between lakes and between years. Water chemical and physical properties are used to gain insight into the inputs and outputs of each lake, and the changes in estimated water balance between years. This information will be used to determine the impact of different hydrological conditions on water chemistry. Results of water isotope tracers of the twenty lakes indicate that there are important year-to-year changes in the water stable isotopes, indicating inter-annual variations in evaporation rates, suggesting that these lakes are sensitive to changes in summer climatic conditions. Preliminary analyses of the ionic concentrations of the lakes suggest that ion concentrations generally decrease throughout the study period, and largely vary together, signifying the hydrological processes controlling the lake water balances are related to climate variability. This research will provide insights into the hydrologic response of lakes in a continuous permafrost region to long-term climatic change.
The Magic Circle: An Exploration in Immersive Theatre
Authors: Baker Amanda 
Published: April 2021

When discussing theatre, most people will imagine a traditional audience-actor relationship, likely in a proscenium setting; the actors on stage inhabit the world of the story while audience members remain passive bystanders. Immersive theatre challenges this convention by bringing the audience into the world of the story. Comparable to being immersed in water, the audience members are fully submerged in this new world; senses are engaged and heightened, and curiosity is peaked. The audience becomes a part of the story world alongside the actors as the border between the real and the fictional becomes blurred. In the world of games and digital media, this border is known as the “magic circle”, a space with unique rules and values separate from day-to-day reality. Though this metaphor was created to describe a game space, it can be argued that audience members in immersive theatre performances have become “players” themselves.
In this project, I explore the “play” aspect of immersive theatre, with a particular focus in the area of pervasive gaming. This project includes research from a variety of theatre practitioners, theorists, and game designers including Janet Murray, Josephine Machon, Katie Salen and Eric Zimmerman. Inspired by that research, I am creating a pervasive game designed to be played in and around the city of Kingston. The goal of this project is to further understand the ways in which theatre and gaming are intrinsically linked while experimenting with form and pushing the boundaries of the magic circle.
Countering Violent Extremism in Canada and Abroad
Authors: Ibrahim Nora Abdelrahman 
Published: April 2021

Terrorism and violent extremism have undoubtedly become among the top security concerns of the 21st century. Despite a robust agenda of counterterrorism since the September 11, 2001 attacks, the evolution of global terrorism has continued to outpace the policy responses that have tried to address it. Recent trends such as the foreign fighter phenomenon, the rampant spread of extremist ideologies online and within communities, and a dramatic increase in terrorist incidents worldwide, have led to a recognition that “traditional” counterterrorism efforts are insufficient and ineffective in combatting these phenomena. Consequently, the focus of policy and practice has shifted towards countering violent extremism by addressing the drivers of radicalization to curb recruitment to extremist groups. Within this context, the field of countering violent extremism (CVE) has garnered attention from both the academic and policy-making worlds.
While the CVE field holds promise as a significant development in counterterrorism, its policy and practice are complicated by several challenges that undermine the success of its initiatives. Building resilience to violent extremism is continuously challenged by an overly securitized narrative and unintended consequences of previous policies and practices, including divisive social undercurrents like Islamophobia, xenophobia, and far-right sentiments. These by-products make it increasingly difficult to mobilize a whole of society response that is so critical to the success and sustainability of CVE initiatives. This research project addresses these policy challenges by drawing on the CVE strategies of Canada, the US, the UK, and Denmark to collect best practice and lessons learned in order to outline a way forward.
Study of chlorophylls and carotenoids in Sansevieria hyacinthoides leaves
Authors: Velma V. , Kyslychenko V. , Velma S. , Popyk А. 
Published: April 2021

Topicality. Sansevieria hyacinthoides (L.) Druce belongs to the Asparagaceae family. The plant is native to African countries. It has been introduced and naturalized in some countries of America, Asia, Australia and Europe. This species is grown as an ornamental plant in many countries, and as a medicinal plant in Africa.
Aim. To determine the quantitative content of chlorophylls a and b and the amount of carotenoids in Sansevieria hyacinthoides leaves freshly collected and dried.
Materials and methods. The quantitative content was determined by the spectrophotometric method. This method allows determining the amount of chlorophyll a and b and carotenoids by the characteristics of the absorption spectra without their prior separation.
Results and discussion. The amount of chlorophyll a and b in the dried leaves was almost 7 times higher than in the freshly collected ones (1.82 ± 0.036 mg/g vs. 0.25 ± 0.005 mg/g, and 2.08 ± 0.038 mg/g vs. 0.29 ± 0.006 mg/g, respectively). The quantitative content of the amount of carotenoids differed by 3.6 times (0.05 ± 0.001 mg/g in freshly collected leaves, and 0.18 ± 0.004 mg/g in the dried raw material).
Conclusions. The quantitative content of the amount of carotenoids, chlorophyll a and chlorophyll b in freshly collected and dried leaves of Sansevieria hyacinthoides has been determined by the spectrophotometric method. The dried plant raw material of Sansevieria leaves has a higher content of biologically active substances: chlorophyll a – 1.82 ± 0.036 mg/g, chlorophyll b – 2.08 ± 0.038 mg/g, and the amount of carotenoids – 0.18 ± 0.004 mg/g.
Prospects of creating a new medicine based on biologically active substances of bearberry leaves for correction of the metabolic syndrome
Authors: Chaika N. , Koshovyi O. , Mazen M. , Kravchenko A. , Kovalyova A. , Kireyev I. 
Published: April 2021

Topicality. The metabolic syndrome is pathogenetically interrelated metabolic disorders in the condition of a sick person. A large set of factors is involved in its occurrence. Risk factors include genetic predisposition, overeating, insulin resistance, obesity, bad habits, hypodynamics, stress and unfavorable environmental conditions. First of all, defects of the lipid and carbohydrate metabolism provoke a cascade of genetic, metabolic, hormonal, nervous, inflammatory and other reactions and disorders in cells, tissues and organs, causing the metabolic syndrome and associated diseases, such as diabetes, kidney and gallstone disease, hypertension, platelet hyperaggregation, etc. Therefore, the rational use of synthetic and herbal medicines in the complex correction of these disorders can slow down the development of the metabolic syndrome.
Aim. To develop the method for obtaining a dry modified extract from bearberry, study its chemical composition, hypoglycemic and hypolipidemic activity in order to determine the prospects of its use for the correction of the metabolic syndrome.
Materials and methods. The study object was a dry extract of bearberry leaves modified with cysteine. HPLC and spectrophotometry were used to analyze the extract obtained. The hypoglycemic and hypolipidemic activity of dry extracts of bearberry was studied in rats with insulin resistance.
Results and discussion. The method for obtaining a dry modified extract from bearberry leaves was developed by adding cysteine. Phenologlycoside (arbutin), 2 phenolic acids (gallic and ellagic), 6 flavonoids, 8 saponins were identified in the extract, and their quantitative content was determined. Hyperoside and catechin were dominant among flavonoids, and ursolic acid, uvaol, and lupeol prevailed among saponins. The content of the main groups of phenolic compounds was determined in the extract by spectrophotometry. The introduction of the dry extract from bearberry leaves modified with cysteine has a normalizing effect on metabolic disorders on the background of a high-fructose diet; therefore, it can be a promising agent for the correction of the metabolic syndrome.
Conclusions. As a result of the research conducted, a new dry extract from bearberry leaves modified with cysteine has been created. The phytochemical composition, hypoglycemic and hypolipidemic activities of the extract have been studied, indicating the prospects for its use to correct the metabolic syndrome.
The pharmacoepidemiological analysis of the influenza pharmacotherapy in Ukraine
Authors: Balitska O. , Zlahoda V. , Hryhoruk Yu. , Cordon O. 
Published: April 2021

Influenza and other acute respiratory viral infections (ARIs) are the most common among human diseases that require timely medical attention and treatment with the most effective drugs.
The aim of the study is pharmacoepidemiological analysis of drugs for the treatment of influenza registered in Ukraine.
Materials and methods of research. The study was based on data from the State Register of Medicines of Ukraine, information on the results of the epidemic season of influenza and acute respiratory infections of the Center for Public Health of the Ministry of Health of Ukraine, declared drugs under the International Nonproprietary or Common Name in Ukraine as of January 2021. Methods: retrospective, descriptive and frequency analyzes.
Results and discussion. A pharmacoepidemiological analysis of influenza drugs in Ukraine was conducted. It was found that the incidence of influenza and SARS during the study period decreased by 3.1% of the total population. Fatalities due to influenza and SARS increased by 41 cases during the study period, which may be related to the coronavirus pandemic. According to the results of a marketing study of antiviral drugs, it was found that the largest share in the structure of registered trade names are interferons (11 trade names).
Conclusions. The analysis of the market showed that among the antiviral drugs registered in Ukraine for the studied period the dominance of domestic drugs is noted - 54% (respectively of foreign origin - 46%).
Analysis of the distribution of domestic analogues of antiviral drugs by manufacturers found that the largest (5 and 4 TN) belongs to LLC "Research and production company" Interpharmbiotek and FZ "Biopharma" Ltd., Ukraine, Bila Tserkva.
Key words: influenza; pharmacoepidemiological analysis; antiviral drugs
ELECTRONIC SIGNATURE IN THE IMPLEMENTATION OF MAIN DUTIES AND JUDICIAL INSTITUTION FUNCTIONS
Authors: Sudarsono  , Halim Abdul 
Published: April 2021

One of the important elements in the Electronic Court System (e-Court) is the electronic signature as regulated in article 26 of the Supreme Court Regulation No. 1 of 2019. In addition to the electronic litigation system, electronic signatures will also be very useful in the implementation of basic tasks of the judiciary, both in trial administration and general administration of the court. This research will discuss electronic signature in court administration as the main topic and will be elaborated with several related topics which include the task of the judicial institution, the electronic signature in the judicial system, person in charge of electronic signature in court administration, and the validity of documents with an electronic signature. The result of the research shows that electronic signature is crucial on implementation of court functions which are judicial function, regulatory function, and executive function performed by the court. Electronic signature creates the process of the case, trial, and general administration in court become more effective, efficient, and eco-friendly, and it also will increase public trust and security of the electronic transaction. Judicial documents that are electronically signed by authorized officials have legal force and legal consequences that can be used for legal remedies, evidence, and so on. For these reasons, it is necessary for the Supreme Court issuing the regulation on the implementation of electronic signatures in judicial institutions in performing their main tasks and functions.
The overview and role of heat shock proteins (HSP) especially HSP 60 and 70 in reproduction and other pathologies (a literature review)
Authors: Berestoviy V.O. , Mahmood Ahmad , Venckivska I.B. , Ginzburg V.G. , Sokol I.V. , Berestoviy O.O. , Govsieiev D.O. 
Published: April 2021

A search of peer-reviewed articles regarding heat shock proteins (HSP’s) especially HSP 60 and 70 was conducted in this review to understand its role in the development of various complications like miscarriage, preterm birth, tubal infertility and spontaneous abortion associated with chlamydial HSP 60 in IVF, male infertility, preeclampsia, cancer, immune system activation, autoimmune diseases, coronary heart disease, dysregulation of steroidal hormone from the endometrium and its up-regulation in stress response. ELISA, western blotting, immunofluorescence, and affinity chromatography were the most common methods researchers used to determine and separate HSP 60 and antibodies related to it. Heat shock proteins are responsible for normal folding of other proteins and prevent its abnormal folding and cause degradation of abnormally folded proteins, mitochondrial protein transport, DNA metabolism, regulation of apoptosis are their significant functions. HSP 60 is a homologue of bacterial HSP 60 (GroEL) and needs co-chaperonin HSP 10 for its proper functioning. Gynaecological and obstetrical complications were more prevalent in most studies. Pregnant women were mostly affected subjects. Abnormal HSP 60 leads to a high level of unfolded or misfolded proteins, which in turn activate other body systems to produce the clinical outcome. Some researchers stated that there is no association between preterm birth and HSP 60 & 70, chlamydial HSP 60 antibodies trigger tubal infertility, preeclamptic pregnancies has detectable HSP60 as compared to control, GroEL leads to tubal infertility and IVF failure, chlamydial (CHSP 60) activates autoimmunity. HSP60 seropositivity reduces the opportunities of ectopic pregnancy, levels of HSP 60 does not stay constant throughout the menstrual cycle in reference to control, while other opposed these conclusions in their research works. According to some researchers, HSP 60 is a risk factor for pregnancy-related pathologies development, and some other opposed this theory and considered HSP 60 as a safety factor for normal pregnancy outcome, according to this review harmful effect of HSP 60 dominate, in future further high-quality studies need to be done for better understanding.
Chronic monocytic leukemia with transformation into acute monocytic leukemia
Authors: Shponka I.S. , Pesotskaya L.A. , Korolenko H.S. , Hutnik I.O. , Murashevych B.V. , Nikonenko V.A. 
Published: April 2021

Chronic myelomonocytic leukosis (CMML) is rarely diagnosed and amounts to 1 per 100 thousand of adults per year, more often in men over 60 years. The clinical case of the rare, prolonged course of myelodysplastic chronic myelomonocytic leukosis (MD-CMML) in a middle-aged woman with rapid transformation into acute monocytic leukemia (AMoL-M5в) with the atypical fulminant course is presented. A retrospective analysis of the course of the disease drew attention to the severe vasculitis suffered by the patient 19 years ago, which could be regarded as the debut of CML in the presence of characteristic pathological changes in the hemogram. Non-pronounced clinical manifestations in the form of moderate cervical lymphadenopathy, skin lesions in the form of transient erythema, spotty eruptions over the next 10 years, fit into the clinical picture of MD-CMML. A detailed picture of the disease was observed after viral infection, bronchitis, antibiotic therapy. Absence of significant blastemia and severe inhibition of normal hematopoiesis with expressed extramedular manifestations of the disease in the patient were not typical for the course of AMoL-M5b in this case. The progression of skin lesions was noteworthy, which gave reason for unfavorable prognosis. For several weeks, the spread of erythematous elements was observed throughout the body with itching, not controlled by antihistamines and corticosteroid drugs; the appearance of maculopapular rashes, merging in places; small-point hemorrhages like vasculitis over the entire surface of the skin. Notable was the development of severe hemorrhagic syndrome without severe thrombocytopenia, significant changes in the coagulogram, as a manifestation of early severe coagulopathy.
The experience of using dexmedetomidine as an adjuvant of anesthesia in ophthalmic surgery
Authors: Mynka N.V. , Kobelyatskyy Yu.Yu. 
Published: April 2021

Various techniques are applied to reduce the severity of postoperative pain and discomfort in patients. The purpose of this research work was to evaluate the effectiveness and safety of Dexmedetomidine as an adjuvant of anesthesia in ophthalmic surgery. The study included 80 patients who underwent corneal transplantation on the basis of Dnepropetrovsk Regional Clinical Ophthalmologic Hospital. Patients were divided into 2 groups: control (group K) – 30 men and main (group D) – 50 ones. Multicomponent balanced anesthesia was applied in both groups. Sibazone was administered as the sedative medicine in the group K, Dexmedetomedin was administered in the group D. The main criteria for evaluating the research results were hallmarked: hemodynamic stability during surgery, the amount of administered opiates, the severity of intraoperative pain syndrome by evaluating the ANI index (ANI – analgesia nociception index), the severity of postoperative pain syndrome and the frequency of postoperative nausea and vomiting (PONV). Both schemes of anesthesia allowed avoiding pronounced fluctuations in hemodynamic parameters and gas exchange at all stages of the study. Analyzing the severity of intraoperative pain, we found that in group K pain relief could be considered insufficient during the first 7 minutes of the most traumatic stage of the surgery, while in group D the ANI index did not fall below 50. Statistically significant differences were obtained on minute 1, 2, 5, 6, and 7 of the surgery. The number of episodes of insufficient anesthesia during the most traumatic stage of the surgery in group K was statistically significantly higher than in group D. Analyzing the quality of pain relief in the postoperative period it was determined, that the level of pain on the Visual Analog Scale (VAS) after awakening in both groups was equal to 0. At the next three stages of the study (2 hours, 6 hours after surgery, and the next morning), the level of pain in group K was significantly higher than in group D. In addition, it was determined that the need for narcotic analgesics and the number of episodes of postoperative nausea and vomiting in group K was statistically significantly higher than in group D. These given data allow us to conclude that Dexmedetomedin is the effective adjuvant of the anesthesia for corneal transplantation.