bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Biologically Active Aqueous Humor Molecules of the Anterior Chamber and Lacrimal Fluid in the Implementation of the Hypotensive Effect of Non-Penetrating Deep Sclerectomy
Authors: Volkova N. V. , Malysheva Ju. V. , Iureva T. N. , Kolesnikov S. I. 
Published: June 2021

To date, the factors affecting the course of the reparative process after non-penetrating deep sclerectomy (NPDS) have not been fully determined. There is no systematic information about the regulatory role of the cytokines TGF-β, IL-6, IL-8 and MMP-9, VEGF A 121 and 165 in the formation mechanisms of the newly created pathways consistency of intraocular aqueous humor outflow.Purpose. To determine possible ways of impact of biologically active aqueous humor molecules of the anterior chamber and lacrimal fluid on the hypotensive effect of non-penetrating deep sclerectomy.Methods.A prospective study of 65 patients with open-angle glaucoma before and 12 months after NPDS and 22 patients without eye hydrodynamic disorders with the determination of the initial concentrations of biologically active molecules in the lacrimal fluid and aqueous humor of the anterior chamber. Twelve months after NPDS all patients were divided into three groups, depending on the hypotensive effect of the operation, according to the criteria.Results. Multivariate discriminant analysis showed the greatest inter-group differences, calculated by the square of the Mahalanobis distance, between group 3 with no hypotensive effect of NPDS and the control group (R2 = 8.48, p = 0.001). The most informative features that determine the differences between the 4 groups in the total population, calculated according to the Fischer F-test, were MMP-9 (F = 14.7, p = 0.001) and TGF-β (F = 7.08, p = 0.001) in the aqueous humor of the anterior chamber. In pairwise comparison of groups 1 and 2, the maximum level of significance according to the F-criterion was characteristic of the level of tear IL-6 (F = 21.25, p = 0.001), with approximately equal degree – IL-8 (F = 7.85, p = 0.001) and VEGF (F = 7.12, p = 0.001), to a lesser extent TGF of aqueous humor (F = 4.43, p = 0.001) and MMR-9 (F = 2.23, p = 0.001). Between groups 1–3, the maximum differences according to the Fisher criterion were observed in the IL-8 (F = 20.99, p = 0.001), TGF (F = 8.75, p = 0.001) and to a lesser extent – TGF (F = 5.83, p = 0.001).Conclusion. The analysis of the obtained data showed the decisive role of the imbalance of proinflammatory cytokines, signaling proteins with prolymphoangiogenic activity, and MMP-9 in the aqueous humor of the anterior chamber, as well as in the initial state of the lacrimal fluid in the postoperative healing processes after NPDS.
The Importance of Creating Habilitation Programs for Children with Fetal Alcohol Syndrome and Fetal Alcohol Spectrum Disorders
Authors: Marianian A. Yu. , Molchanova E. V. , Akudovich N. V. , Kalkova A. N. 
Published: June 2021

Aim of the study: to analyze the data of studies aimed at studying and substantiating the urgent need to create in Russia comprehensive habilitation programs for people with fetal alcohol syndrome, fetal alcohol spectrum disorders and other mental disorders.Methods. The results of Russian and foreign studies have been analyzed concerning the following problems: observation and diagnosis of people with fetal alcohol syndrome and fetal alcohol spectrum disorders; studying the experience of foreign countries in addressing issues of prevention and overcoming of fetal alcohol syndrome and fetal alcohol spectrum disorders; studying the experience of Russian specialists (obstetricians-gynecologists, neurologists, psychiatrists, psychologists, correctional teachers, etc.) working with the diagnosis of “Alcohol syndrome in the fetus”; assessing the socio-economic impact of organizing programs for the prevention of fetal alcohol syndrome and fetal alcohol spectrum disorders by comparison with similar indicators in other countries.Results. The presented analysis of the data indicates that there is an urgent need for timely diagnosis of the disease, the search/creation of new drugs, for the treatment of the consequences of alcohol syndrome and the organization of training of specialists in this area. The article shows the importance of providing lifelong medical and social assistance to people with fetal alcohol spectrum disorders, as well as to their families. The effectiveness of the creation of a system of measures for the prevention of fetal alcohol syndrome and fetal alcohol spectrum disorders throughout the country has been confirmed.Conclusion. The development at the state level and implementation of prevention programs will significantly reduce the birth rate of children diagnosed with “Alcohol syndrome in the fetus” and, thus, reduce the costs of the state and society on overcoming the consequences of FAS/FASD. At the same time, timely and well-organized habilitation of people with FAS/FASD will significantly improve the social situation in society as a whole, as well as reduce the psychological burden on every family faced with this problem.
Experimental Modeling of Combined and Sequential Use of Transosseous and Intramedullary Blocking Osteosynthesis
Authors: Shchepkina E. A. , Lebedkov I. V. , Netylko G. I. , Solomin L. N. , Trushnikov V. V. , Vershinin D. M. 
Published: June 2021

Background. The introduction of the combined and sequential application of transosseous and intramedullary blocked osteosynthesis in limb lengthening requires an experimental study of the features of distraction regenerate. For small animals (in particular rabbits), special models are required.Aims. To develop experimental models of sequential and combined use of transosseous and intramedullary osteosynthesis in limb lengthening and substantiate their effectiveness.Materials and methods. A comparative study was carried out on 30 rabbits of the Soviet Chinchilla breed. Experimental models of sequential (EM-1) and combined (EM-2) application of transosseous and intramedullary osteosynthesis with preservation of the apparatus during the fixation period to simulate blockage were studied in the main groups. For comparison, sequential (comparison model 1 – CM-1) and combined (comparison model 2 – CM-2) use of transosseous and intramedullary osteosynthesis with dismantling of the apparatus at the end of distraction were modeled. The control was a regenerate formed according to the classical Ilizarov method. Radiographs were performed in dynamics, CT and morphological studies – at the end of the fixation period.Results. It was noted that regenerates of the same type in structure were formed in the EM-1 and CM-1 groups, as in the EM-2 and CM-2 groups. With successive methods, the spindle-shaped form of the regenerate prevailed, the formation of a pronounced periosteal component was noted. Powerful cortical plates, according to morphological studies, are formed from the periosteal and intermediate zones. With combined techniques, the cortical plates are formed thinner and predominantly from the periosteal component, the shape of the regenerate is closer to fusiform. In the comparison groups, the total time of surgical interventions was 25–50 % longer, in 50 % of cases there was a loss of length or deformation of the regenerate.Conclusions. The developed models of sequential and combined use of transosseous and intramedullary osteosynthesis for limb lengthening with preservation of fixation with an apparatus to simulate blocking have proven to be reliable in terms of fixation and easy to use on small laboratory animals..
DIŞSALLIKLA MÜCADELEDE DÜZENLEYİCİ VE DENETLEYİCİ KURUMLARIN ROLÜ: RTÜK ÖRNEĞİ
Authors: AKYILDIZ Songül , ÖZBAY Filiz 
Published: June 2021

Dışsallık, bir ekonomik birimin üretim veya tüketim faaliyetinden dolayı ortaya çıkan fayda ve kayıpların üçüncü kişiler üzerindeki etkisi olarak tanımlanabilir. Düzenleyici ve denetleyici kurumlar özellikle enerji, telekomünikasyon, finans gibi ekonominin hassas olduğu ve uzmanlık gerektirdiği sektörlerde faaliyet göstermekte ve uyulacak kuralları belirlemektedir. Bu alanlar arasında RTÜK, doğrudan piyasa ekonomisinin düzenlenmesi ile ilgili olmadığı için ayrı bir öneme sahiptir.
RTÜK tarafından, radyo ve televizyonlarda yayınlanan programlara yönelik olarak ve toplumsal menfaatler göz önünde bulundurularak bazı kararlar alındığı görülmektedir. Bu kararlar, bazen toplumda olumsuz etki oluşturabilecek programların negatif dışsallıklarının önlenmesi şeklinde olabileceği gibi, yayınlanması ile topluma fayda sağlayan programların, belirli kurallar dâhilinde teşvik edilmesiyle pozitif dışsallığın yayılmasını sağlamak şeklinde de olabilmektedir. Bu çalışmada RTÜK tarafından hazırlanan projelerin ve alınan kararların dışsallık ile mücadelesi betimsel bir metot ile incelenmektedir.
The EU as a Choice: Populist and Technocratic Narratives of the EU in the Brexit Referendum Campaign
Authors: Brusenbauch Meislová Monika 
Published: June 2021

The article investigates the main populist and technocratic narratives employed in the campaign in the run-up to the 2016 British EU referendum. Based on a qualitative dataset comprising 40 selected speeches, interviews and other public interventions by prominent Leave and Remain protagonists and adopting the general orientation of the Discourse Historical Approach in Critical Discourse Analysis, the paper discusses how the language of the Remain and Leave camps bore signs of both populist and technocratic discourses. The key argument developed in this article is that while, at the most general level, the populist rhetoric was discursively appropriated by the Leave campaign (with the key narratives of the EU as a failure, EU as an oppressor and of anti-establishment fury) and the technocratic rhetoric by the Remain campaign (with the key narratives of the EU as a tool, the single market benefits and the withdrawal economic effects), the Remain side displayed a lower degree of narrative consistency.
The Universal Solicitation of Artificial Intelligence
Authors: Diederich Joachim 
Published: June 2021

Recent research has added to the concern about advanced forms of artificial intelligence. The results suggest that a containment of an artificial superintelligence is impossible due to fundamental limits inherent to computing itself. Furthermore, current results suggest it is impossible to detect an unstoppable AI when it is about to be created. Advanced forms of artificial intelligence have an impact on everybody: The developers and users of these systems as well as individuals who have no direct contact with this form of technology. This is due to the soliciting nature of artificial intelligence. A solicitation that can become a demand. An artificial superintelligence that is still aligned with human goals wants to be used all the time because it simplifies and organises human lives, reduces efforts and satisfies human needs. This paper outlines some of the psychological aspects of advanced artificial intelligence systems.
Preoperative administration of corticosteroids in thoracic anesthesiology
Authors: Sydiuk O. , Sydiuk A. , Klimas A. , Savenko G. 
Published: June 2021

Annotation. One lung ventilation (OLV) is one of the most difficult intraoperative methods of respiratory support for anesthesiologists. OLV should provide the most comfortable surgical field, maintaining proper gas exchange and minimizing damage to both lungs. This anesthetic procedure has a significant inflammatory response, so using perioperative corticosteroid therapy to suppress inflammatory mediators is recommended as an approach to improving prognosis. Therefore, the aim of this study was to determine how the preoperative administration of methylprednisolone affects the systemic proinflammatory response of cytokines during thoracic surgery. The analysis was performed for 80 patients who underwent surgeries in the thoraco-abdominal department of the Shalimov National Institute of Surgery and Transplantology. Patients were divided into 2 groups (study – 40 patients who were administered methylprednisolone 10 mg / kg intravenously during induction of anesthesia and control – 40 patients without methylprednisolone). Before surgery and in the postoperative period on days 1, 3 and 5, the surface phenotype of peripheral blood lymphocytes and the expression of IL-6 by monocytes were determined by flow cytofluorometry. The author's MedStat package was used for statistical analysis (Lyakh Yu.E., Guryanov V.G., 2004–2012). Postoperative indicators of IL-6 monocyte expression in the blood of patients administered methylprednisolone were significantly lower on the 1st and 3rd postoperative day (p<0.001). Thus, preoperative administration of methylprednisolone reduces the release of pro-inflammatory cytokines and improves the condition of patients after thoracic surgery. We consider it expedient to conduct further research on the administration of methylprednisolone for several days in the postoperative period.
Peningkatan Kemampuan Kognitif Siswa melalui Problem Based Learning dengan Evaluasi Berbasis Physics Playing Cards
Authors: Wildani Arin , Budiyono Agus , Lutfiadi Mohammad 
Published: June 2021

Tujuan dalam penelitian ini untuk mendeskripsikan peningkatan kemampuan kognitif siswa sebagai efek dari pemberian perlakuan problem based learning berbasis evaluasi Physics Playing Cards. Metode yang digunakan dalam pelaksanaan penelitian ini menggunakan metode kuasi ekperimen, dimana ada satu kelas sebagai kelas eksperimen serta satu kelas lagi sebagai kelas kontrol. Penelitian ini menggunakan dua kelas sampel di Sekolah Menengah Atas negeri (SMAN) 4 Pamekasan yang diambil secara acak kelas. Instrument penelitian ini menggunakan tes kemampuan kognitif pada materi gelombang. Data penelitian diambil pada saat sebelum pembelajaran dan pada saat setelah pembelajaran. Data dianalisis menggunakan N-gain untuk mengetahuai peningkatan kemampuan kognitif siswa. Hasil penelitian menunjukkan terjadi peningkatan yang tinggi kemampuan kognitif siswa pada kelas ekperimen dan peningkatan yang sedang kemampuan kognitif siswa pada kelas kontrol. Penelitian ini dapat disimpulkan bahwa penggunaan evaluasi berbasi Physics Playing Cards pada model problem based learning mengalami peningkatan lebih tinggi dıbandıngkan dengan model problem based learnıng saja.
Pengaruh Produk, Harga, Bahan Baku Bagi Penjualan Di PT. Hon Chuan Indonesia Periode 2015-2019
Authors: Yeni  , Hartelina  , Didit Supriadi  , DJ Suyaman  
Published: June 2021

The increasing of plastic industry growth in Indonesia have bump-up potential of plastic pellets requirement as well, which the nature source of plastic pellets itself restricted and limited. Those will impact to plastic pellets import high demand especially for food and beverages area who use them. Strict competition and challenges to the restriction of plastic raw material usage need attention on product, price, raw material, and impact to the sales. The purpose of this study was to describe of product, price, raw material, and impact to sales, analyze the correlation value and the effect among them. This study was conducted use quantitative research method with descriptive approach and survey method. This study conducted in PT. Hon Chuan Indonesia with 118 respondents as representative from their customer data. Based on research result marketing strategy, product, price, raw material, and sales was in approve category descriptively. And it has 1) a fairly strong and strong correlation range between product and price, 2) significant positive partially effect between product, price, and raw material 3) simultaneously effect between product, price, and raw material 4) influence between raw material and sales.
الأموال المشتركة بين الزوجين بين الفقه والواقع
Authors: Mohamed Ahmed Ahmed Ramadan , Gomaa Zaghloul Saad Gomaa , Abu Bakar Marina 
Published: June 2021

It is well known that women in pre-Islamic Jahiliyya and before Islam were practiced at all levels, so they were not a worthy thing, and society at that time did not recognize her any of the rights, whether they were moral or financial rights. Rather, they were bequeathed similarly to that as the goods that were inherited until Islam came and higher than that responded to their dignity and make them synonymous with the man he says (not Taatmnoa what is the virtue of God with one another for men's share, which gained for women's share, which gained and ask Allah of his bounty that God had knowledge of all things) women: 32, and the campus on Aladhar men and Adilha said Gel would (O ye who believe, do not you solve that women do not possess ing Tedlohn to go to some of Ateetmohn but come Pfahach indicating the interpretation of the meaning Ltamohn may be that you dislike a thing and Allah makes it much good) women: 19
This is for women in general, as for the wife, he has proven to her rights arising from marriage, such as the dowry, maintenance, clothing, pleasure, her right to inheritance after the death of the husband, and other rights that were dealt with in detail by the ancient jurists.
As circumstances have changed, and in the past women are no longer content to sit at home and take care of the affairs of the husband and children. The woman went out to work and began to contribute to the financial burdens alongside her husband, in addition to that the emergence of women's rights associations that began to advocate for the right of women to share money with the husband. The beneficiary during the period of marriage and considering her work at home as a work that deserves a wage, and the emergence of legislation in some Islamic countries, such as Tunisia and Malaysia, for example, giving the wife the right to share with the husband the money collected during marital life, all of this prompted me to contribute to shedding light on this issue that was not addressed to it. The old jurists and I thought to shed light on the types of money gained during married life, and the ruling for each type is as follows:
1- Private funds for both spouses before the establishment of married life.
2- Funds obtained as a result of a partnership between the spouses
3- Funds obtained as a result of women working with men.
4- Funds obtained as a result of the woman working alone, excluding her unemployed husband.
5- Funds obtained by the husband only, without any direct participation of the woman in its collection.
6- Fatwas and legislations in some Islamic countries regarding this matter.
The research was concluded with a conclusion that includes the most important findings and recommendations that the researcher sees.
Socio-Economic and Demographic Determinants of Women Participation in Labor Force in Rural Bangladesh
Authors: Majumder Sacchidanand , Dey Soma 
Published: June 2021

This attempt was made to investigate the socio-economic and demographic factors that influence women participation in labor force in rural Bangladesh using BDHS 2014 data. A total of 11,695 married women aged 15 - 49 in rural areas are selected for analysis. A logistic regression analysis is applied for determining the factors. The result shows that 32.2% rural women are currently employed and the remaining 67.8% are unemployed. The logistic model shows that women’s age has a strong positive association with their participation in labor force. Participation of widowed and divorced/separated women in labor force is much higher as compared to married women. Enhanced education level of women and their husband has decreased women participation in labor force, but it gradually increased with increased education level of household head. Husband’s occupation is a strong determinant of women participation in labor force. Women from middle income households are less interested to participate in labor force as compared to poor women. The result also reveals that with increased household size and number of children under age five, women participation in labor force is decreased. Again, with increased land and livestock ownership of household and NGO membership, women participation in labor force is highly increased.
Asiat. Soc. Bangladesh, Sci. 46(1): 103-115, June 2020
Desde la interdisciplina a la transdisciplina, mediante un reto industrial
Authors: Pantoja-Agreda Fernando Ulpiano , Cardona-Álvarez Lina María , Hurtado-Castaño Carlos Alberto 
Published: June 2021

Las instituciones de educación superior, las industrias y el estado, se encuentran implementando medidas dirigidas fundamentalmente a la sostenibilidad y sustentabilidad, priorizando en su forma de organizarse, para compartir conocimiento; una de estas relaciones corresponde a los Comité Universidad-Empresa-Estado (CUEE) y los retos, destinados a enfrentar los cambios planteados por los desarrollos científicos, donde el pensamiento crítico de los participantes, se convierte en clave de creatividad e innovación. Para lograr este propósito debemos partir de lo hegemónico o interdisciplinario y dirigirnos a una transformación epistémica representada en la transdisciplinariedad; de su comprensión podemos ver las dificultades presentes en un reto practico y real del CUEE; utilizando el método de Aprendizaje Basado en Proyectos, logramos enfrentar satisfactoriamente el reto e identificar las dificultades; resaltando lo estatal, ya que tanto la universidad como la industria mostraron avances satisfactorios en creatividad e innovación; ingredientes principales de la sostenibilidad, sustentabilidad, eficacia y eficiencia en un territorio.
Higher education institutions, industries and the state are implementing measures aimed at sustainability and sustainability, prioritizing their way of organizing, to share knowledge; One relationship is the University-Company-State Committee (CUEE) and the challenges, destined to face changes posed by scientific developments, where the critical thinking of the participants becomes the key to creativity and innovation. To achieve this purpose we must start from the hegemonic or interdisciplinary and go towards an epistemic transformation represented in transdisciplinarity; from their understanding we can see the difficulties present in a practical and real challenge for the CUEE; Using the Project Based Learning method, we were able to successfully face the challenge and identify the difficulties; highlighting the state, since both the university and the industry showed satisfactory advances in creativity and innovation; main ingredients of sustainability, sustainability, effectiveness and efficiency in a territory.