bluuebunny/crossref_metadata_2025_split huggingface dataset:
Total Hip Arthroplasty for Complex Primary Hips – A Tertiary Center Experience
Authors: Vidyarthi Amit Ranjan , Barman Riddhideb , Kisku Lawrence , Akhtar Mohammad Nasim , Keshkar Sanjay 
Published: December 2021

Background:
Total hip arthroplasty (THA) surgery for complex primary hips are challenging not only for its technical difficulties but also for increased risk of complications, thus requiring detailed planning to ensure successful operation. This paper aims to present the pattern of complex primary hips presenting for total hip replacement and the challenges and complications.

Materials and Methods:
This was a retrospective study in which records of patients who had THA from 2015 to 2019 were analyzed for the demography, pattern of complex primary hip, and the surgical challenges and complications. Outcome of follow-up results was analyzed by clinical (Harris Hip Score) and radiological evaluation at 6 weeks, 3 months, and 2 years.

Results:
One hundred THAs were done during the study period, out of which 42 THAs in 29 patients (16 unilateral and 13 bilateral THAs) were of complex primary hip. Majority of them were of ankylosing spondylitis (38.1%) followed by posttraumatic avascular necrosis of femoral head (23.8%). The main difficulties were related to soft-tissue contracture, completely fused hip, and removal of hardware in old operated hip fracture. Postoperatively, majority of the patients had anemia (7 patients, 16.6%), followed by postoperative dislocation in 2 patients (4.7%). Outcome of follow-up results was analyzed by clinical (Harris Hip Score) and radiological evaluation at 6 weeks, 3 months, and 2 years, and the overall outcome was satisfactory in 95% of the patients.

Conclusion:
Complex THA is challenging and needs to assess properly and to be done meticulously. The surgical exposure and subsequent placement of components can be significant challenges in complex THA which can be tackled by using proper instrumentation and modular implants. With proper surgical technique, proper instrumentation, and proper implantation, one can expect good-to-excellent results even in complex THA.
Effectiveness of Megestrol for the Treatment of Patients with Atypical Endometrial Hyperplasia or Endometrial Endometrioid Adenocarcinoma (Stage IA, Well Differentiated)
Authors: Akhavan Setareh , Sabet Fahimeh , Mousavi Azam-Sadat , Gilani Mitra Modarres , Hasani Shahrzad Sheikh 
Published: December 2021

Objective:
We aimed to evaluate treatment responses and recurrence rate of atypical endometrial hyperplasia (AEH) and endometrial endometrioid adenocarcinoma (EA) with Stage IA Grade 1 to megestrol in Iranian patients who are candidates for medical treatments.

Methods:
In a retrospective cohort study that was conducted on 50 patients with AEH and 22 patients with EA who were referred to the oncology clinic of Imam Khomeini Hospital, Tehran, Iran, during 2006–2016, we recruited all patients with AEH or EA of Stage IA Grade 1 and their disease was diagnosed during endometrial curettage with or without hysteroscopy. Patients were initially treated with 160 mg of megestrol daily, along with aspirin up to 3 months, and then after 3–4 weeks of discharge of the drugs, patients underwent curettage with hysteroscopy.

Findings:
The patients with AEH had 31 complete responses and five progressive diseases, and the patients with EA had seven complete responses and seven progressive diseases. After treatment, 25 cases with AEH and 5 cases with EA had an intention to get pregnant, whereas eight patients with AEH and 1 case with endometrial cancer became pregnant. Recurrence occurred in the 2 cases with AEH and 2 cases with endometrial cancer which the time of recurrence in the patients with AEH was longer than in patients with endometrial cancer (P = 0.011).

Conclusion:
Megestrol is an effective therapeutic agent in endometrial hyperplasia or low-grade endometrial cancer patients who are willing to conserve their childbearing.
Patients’ Satisfaction with the Community Pharmacy Services in Iran
Authors: Saffaei Ali , Moghaddas Azadeh , Sabzghabaee Ali Mohammad 
Published: December 2021

Objective:
This study aimed to measure patient satisfaction with community pharmacy in Isfahan, Iran, in 2019.

Methods:
In this cross-sectional study (2019), we selected 104 pharmacies located in the second largest city of Iran (Isfahan) based on systematic random sampling and at least five clients at different times of a day who finished the process of obtaining medications from the pharmacies were randomly selected for a short and structured interview using the Persian version of the MacKeigan and Larson questionnaire for measuring patients' satisfaction with pharmacy services.

Findings:
The reliability of the questionnaire was confirmed after distributing 520 among the patients (r = 0.958). No significant difference was observed between sex, marital status, housing status, and total satisfaction score based on the results. In addition, there was a significant difference between educational levels, location, job status, insurance status, real income, and total score of satisfaction (P < 0.05). Our results revealed acceptable satisfaction in some aspects, such as paying attention to pharmacists, the general condition of the pharmacy, and their technical competence. On the other hand, the patients were not satisfied enough in different aspects, for example, counseling, accessibility to their needed drugs, and expenses.

Conclusion:
Patient satisfaction needs to be improved and enhanced in the case of counseling the patients on their medications, and drug accessibility and expenses remain the primary source of dissatisfaction in the studied population, which should be noted by the Iranian Food and Drug Organization and other related authorities.
FAMILY DOG: resistência pela arte surda
Authors: Menezes Ronny Diogenes de , Souza Fabio Marques de 
Published: December 2021

O objetivo desse artigo é apresentar as Artes Surdas como forma de resistência e denúncia da opressão sofrida por Surdos. Para isso, iremos apresentar a base do pensamento ouvintista opressor, que entende essas pessoas como portadoras de uma enfermidade que precisa ser curada. Porém, essa mesma base determinou o surgimento da Surdidade, que representa a luta de cada Surdo para assegurar a sua existência no mundo. Na sequência discutiremos como o óleo sobre tela, Family Dog, da artista plástica Surda, Susan Dupor, denuncia essa opressão e nos revela a realidade sensível do mundo dos Surdos. Por fim, concluímos que, através das Artes Surdas, é possível conhecer o outro, e nesse caminho humanizar a nossa relação com eles.
POLA DISTRIBUSI PEMASARAN GULA MERAH DI KABUPATEN ENREKANG (Studi Kasus Penrajing Gula Merah Desa Batu Mila Kec.Maiwa)
Authors: Suradi Suradi , Hakim Hakim , Nurdin Zulkifli 
Published: December 2021

Gula merah merupakan salah satu produk sektor agroindustri dengan potensi pasar yang cukup baik, sehingga Perlu untuk dikembangkan. Penelitian ini bertujuan untuk mengetahui: 1) Jenis saluran Distribusi yang digunakan pada sistem pemasaran gula merah di Desa Batu Mila Kecamatan Maiwa; 2) Mengetahui Margin, Biaya serta Keuntungan Pemasaran pada sistem pemasaran gula merah di Desa Batu Mila; 3) Mengetahui Efisiensi pemasaran pada berbagai jenis saluran Distribusi pemasaran gula merah di Besa Batu Mila Kecamatan Maiwa. Pengumpulan data dilakukan melalui survei wawancara dan kuesioner dengan reponden penelitian. Data diolah dengan menggunakan rumus margin dan efisiensi pemasaran. Hasil penelitian menujukan (1) Saluran distribusi pada sitem pemasaran gula merah di Desa Batu Mila Kecamatan Maiwa Kabupaten Enrekang terdapat empat saluran, saluran pertama melibatkan pedagang pengecer sebagai pedagang perantara di dalamnya, saluran kedua terdapat pedagang pengumpul dan pedagang pengecer sebagai pedangan perantara, saluran ketiga juga melibatkan dua pedagang perantara yaitu pedagang besar serta pedagang pengecer sebelum sampai ke konsumnen, serta saluran terakhir tidak terdapat pedagang perantara hanya melibatkan pengrajin dengan konsumen. (2) biaya pemasaran setiap lembaga pemasaran pada empat jenis sistem distribusi gula merah berbeda.
PENGARUH MOTIVASI KERJA DAN DISIPLIN KERJA TERHADAP TERHADAP KINERJA KARYAWAN
Authors: Idrus Ilham , Hakim Hakim , Kamaruddin Yasif 
Published: December 2021

Motivasi kerja adalah hal yang sangat penting dalam meningkatkan suatu efektifitas kerja, karena orang yang memliki motivasi kerja yang baik akan berusaha dengan semaksimal mungkin agar pekerjaannya dapat berjalan dengan apa yang di inginkan.Tujuan dari penelitian ini Untuk mengetahui pengaruh motivasi kerja dan disipilin kerja terhadap kinerja karyawan serta mengetahui variabel mana yang lebih berpengaruh terhadap kinerja karyawan. Adapun metode analisis data yang digunakan dalam penelitian ini Menggunakan pendekatan kuantitatif untuk menganalisis hubungan antar variabel dengan angka atau skala numerik pada PT Industri Kapal Indonesia (IKI).Hasil dari penelitian ini menunjukkan beberapa kategori variabel yaknik, mayoritas responden pada variabel motivasi terbagi menjadi tiga, kategori tinggi memliki jumlah 19 orang presentase 12,4%, sedangkan kategori sedang berjumlah 72 orang presentase 47,1%, kategori rendah berjumlah 62 orang presentase 40,1%. Sedangkan pada variabel disiplin kerja mayoritas responden dalam kategori tinggi berjumlah 19 orang presentase 12,4%, adapun kategori sedang berjumlah 102 orang presentase 66,7% dan kategori rendah berjumlah 32 orang presentase 20,9%.Dapat di simpulkan bahwa menentukan variabel utama yang paling domina terhadap kinerja karyawan PT.Industri Kapal Indonesia diketahui bahwa kedisiplinan yang tinggi sangat mendominan 3,50% dengan adanya kesadaran dan kesedian keryawan untuk menaati semua peraturan dan norma-norma sosial yang berlaku di perusahaan.
The Menace of Drug Addiction in the Family: Challenges, Coping Strategies and Recommendations
Authors: Jamir Singh Paramjit Singh , Azman Azlinda , Drani Syazwani 
Published: December 2021

Malaysia is witnessing a significant impact of drug use among its population which has seen an upward trend in the last decade. Family members of drug users and drug abusers have borne the heaviest brunt and therefore, this research examines how the family member cope with the latter’s’ addiction. Eighteen (18) family members of drug users in Penang, Malaysia were interviewed in this qualitative research. Primary data gleaned from these in-depth interviews were analysed, and findings showed that family members adopted many different coping mechanism and strategies, namely emotional, avoidance, controlling, inactive, assertive and supportive in dealing with challenges of intra family drug addiction. External and internal resources as well as support systems were also accessed. Specifically, close relatives and counsellors from National Anti-drugs Agency were approached for emotional support and practical guidance. This research found affected family members who formed self-help and support groups as part of their coping strategies were able to discover meaningful and useful ways to deal with the destructive effects of drug abuse. Government and non-governmental agencies also assisted affected family members in offering practical help. However, it is important both government and non-governmental agencies play a more proactive role. The National Anti-drugs Agency in particular, it is recommended provide tailor made programmes and coping skills in addressing these traumatic situations and enable families deal with this destructive habit of addiction.
Faktor-Faktor Yang Mempengaruhi Loyalitas Anggota Dojang Di Yogyakarta
Authors: Mega Wijaya Petra Surya , Haiti Maklon 
Published: December 2021

The development of dojang in Yogyakarta shows a pleasant increase because of the increasing number of taekwondo matches on a regional, national and even international scale followed by a large number of dojangs in Yogyakarta. This makes the members of the dojang to compete with each other and even move from one dojang to another because they see that the other dojang is superior to the dojang he is currently attending.
This study aims to examine a number of variables that affect the loyalty of dojang members, including (1) brand image, (2) brand then, (3) satisfaction, (4) servqual, and (5) brand credibility. To answer the research objectives, 100 questionnaires were distributed randomly to a number of large dojang in Yogyakarta. The analytical tool used is multiple linear regression.
The results showed that there were 2 variables that significantly or strongly influenced the loyalty of dojang members, namely (1) brand image, and (2) servqual. While there are 3 variables that do not significantly affect the loyalty of dojang members, namely (1) brand trust, satisfaction, and (3) brand credibility.
Household income as a factor forming potential demand on the market of organic products
Authors: Shyian Dmytro , Herasymenko Yuliia , Ulianchenko Nataliia , Velieva Viktoriya , Kotelnikova Iuliia 
Published: December 2021

Purpose. The purpose of the article is to analyze the situation of households in terms of income, expenditure, food quality, consumption of individual products and to assess the potential development opportunities for organic products market.
Methodology / approach. The dialectical method of cognition, the systematic approach to the study of economic phenomena and processes, the monographic method (the analysis of scientific achievements of domestic and foreign scientists on the assessment of income, cost structure, quality of life) were used in the research. The abstract-logical method (for theoretical generalizations and formulation of conclusions), the economic-statistical method (when assessing the reliability of differences between groups of households), the graphic method (when constructing graphical images), correlation analysis (to make a correlation between the level of consumption of meat and meat products based on the amount of income in the households) were used among the special methods of research. To assess the actual state of affairs, the authors used data from the statistical observation regarding the level of income and expenditures of the population of Ukraine according to 2018, which was called “Anonymous microdata on the main indicators of income, expenditures and living conditions of households”. The total number of households that responded to questions about their income level was 7698 from 8051, or 95.6 %.
Results. The article emphasizes that one of the important criteria for social protection is the quality of food supply in accordance with scientific norms and established standards. The income level and food consumption by households were compared. It was noted that in general the distribution of respondents in cash income levels was not considered to be normal. A clear correlation was established between the level of household income and the level of food consumption in both monetary and physical units. These differences were tested using the statistical method of t-test for comparing averages, which provided evidence of the difference between groups of households.
Originality / scientific novelty. For the first time, the level of discrepancies in income and food consumption between households was assessed using the t-test method of comparison of averages, which allowed establishing statistically a significant difference between groups in these indicators. The assessment of the impact of household income on the level of expenditures and consumption of certain types of food products has been further developed with the identification of promising focus groups for consumers of organic products.
Practical value / implications. The practical value of the results is that the identification of patterns allows to predict further trends in the level of consumption of certain types of food, particularly organic.
Social capital of the agricultural sphere: indicators of measurement for conditions of formation and results of use
Authors: Dymczyk Rafal , Shpykuliak Oleksandr , Hrytsaienko Mykola , Sакоvska Olena , Hrytsaienko Halyna 
Published: December 2021

Purpose. The aim of the article is to reveal the theoretical and methodological approaches to the assessment of social capital and to build a system of indicators of its formation and results of use in the agricultural sector.
Methodology / approach. The theoretical-and-methodological basis of the study are the conceptual provisions of economic theory, which allow determining the principles of creation and use of social capital. In the research we used methods of theoretical generalization, analysis and synthesis (to determine the object and objectives of the study); system approach (to identify components of social capital); systematization and classification (to determine the system of indicators that determine the formation and use of social capital); analysis of hierarchies (for comparative analysis of social capital of agricultural holdings).
Results. Based on a critical review of literature sources, scientific trends in the assessment of social capital were systematized. There are determined new conceptual approaches to the development of indicators of social capital of the agricultural sector for meso- and microlevels, which take into account industry specifics, are determined by groups of factors of its formation and results of use, and reflect the main components of social capital – innovation (norms), relational (trust) and structural (social networks) social capital. On the basis of the method of analysis of hierarchies the comparative it was carried out an estimation of factors of formation of social capital of two domestic agroholdings which results correspond to results of the analysis of indicators of results of its use
Originality / scientific novelty. The methodological bases of the analysis of social capital of the agrarian sphere through complex measurement of its components by means of system of indicators on meso- and microlevels taking into account branch features were improved, factors of formation and results of use of social capital were systematized.
Practical value / implications. The obtained results allow substantiating the key approaches to measuring the social capital of the agricultural sector, which makes it possible to obtain comprehensive information for decision-making regarding its further formation and effective use.
Luspatercept (Reblozyl)
Authors: Reimbursement Team  
Published: December 2021

CADTH recommends that Reblozyl should be reimbursed by public drug plans for the treatment of adult patients with very low- to intermediate-risk myelodysplastic syndromes (MDS)-associated anemia who have ring sideroblasts and require red blood cell (RBC) transfusions, if certain conditions are met.
Reblozyl should only be covered to treat patients who have failed or are not suitable for erythropoietin-based therapy.
Reblozyl should only be reimbursed if prescribed by a specialist in MDS and if the cost of Reblozyl is reduced. Reimbursement should only be renewed if Reblozyl shows benefit to the patient such that the patient no longer requires RBC transfusions.
PENGARUH PEMBELAJARAN JARAK JAUH DENGAN APLIKASI GOOGLE CLASSROOM TERHADAP EFEKTIVITAS BELAJAR BAGI SISWA PADA MATA PELAJARAN PENDIDIKAN AGAMA ISLAM SELAMA PANDEMI COVID-19 DI SMPN 1 PALIMANAN
Authors: Farhan Abdul , Nurlela Nurlela , Iwan Iwan 
Published: December 2021

Latar belakang penelitian ini adalah dampak dari covid-19 khususnya dalam sektor pendidikan, dalam hal ini pendidikan mengalami siklus pembelajaran yang berubah dari metode luring ( luar jaringan) atau pembelajaran yang dilakukan di kelas menjadi metode daring (dalam jaringan) atau pembelajaran yang dilakukan dengan jarak jauh. Pembelajaran jarak jauh merupakan suatu alternatif yang perlu dilakukan oleh lembaga pendidikan untuk tetap menjalankan berlangsungnya proses kegiatan pembelajaran selama wabah covid-19. Salahsatu media yang bisa digunakan dalam proses pembelajaran jarak jauh yaitu dengan aplikasi google classroom. Adapun rumusan masalah dalam penelitian ini adalah: (1) Bagaimana Pembelajaran Jarak Jauh (PJJ) menggunakan aplikasi Google Classroom pada mata pelajaran PAI di SMPN 1 Palimanan?, (2) Bagaimana efektivitas belajar bagi siswa mata pelajaran PAI selama pandemi covid-19 di SMPN 1 Palimanan?, (3) Seberapa besar pengaruh penerapan Pembelajaran Jarak Jauh (PJJ) mata pelajaran PAI dengan menggunakan aplikasi Google Classroom terhadap efektifitas belajar bagi siswa di SMPN 1 Palimanan?. Untuk memperoleh hasil penelitian ini, peneliti menggunakan metode penelitian kuantitatif. Adapun teknik pengumpulan data yang digunakan dalam penelitian ini yaitu: Angket, wawancara, dan dokumentasi. Adapun data yang diperoleh dianalisis dengan melakukan uji variabel dan uji korelasi. Berdasarkan permasalahan di atas dan setelah dianalisis dapat disimpulkan bahwa: (1) Dalam Pembelajaran Jarak Jauh dengan Aplikasi Google Classroom Pada Mata Pelajaran PAI Selama Pandemi Covid-19 Di SMPN 1 Palimanan termasuk kedalam kategori baik. Karena rekapitulasi hasil perhitungan angket diperoleh hasil sebesar 85,5%. (2) Efektivitas Belajar Siswa Di SMPN 1 Palimanan masuk dalam kategori baik karena berdasarkan rekapitulasi hasil penghitungan angket mengenai efektivitas belajar diperoleh hasil sebesar 79,7% yang menunjukkan kategori baik. (3) Terdapat hubungan yang signifikan dan positif antara pembelajaran jarak jauh dengan aplikasi google classroom terhadap efektivitas belajar siswa, karena r bernilai positif. Hal ini dibuktikan dengan perhitungan korelasi dengan menggunakan uji hipotesis korelasi product moment dan didapat nilai koefisien korelasi r sebesar 0,650 yang menunjukkan pada korelasi yang cukup signifikan.
UJI VALIDITAS SABAROUD GLUKOSA AGAR HIPERTONIK UNTUK MENDETEKSI Candida sp
Authors: Widyanti Tuty , Basarang Mujahidah , Afiah Nurul 
Published: December 2021

Jamur merupakan agen yang juga memberi pengaruh pada penyakit paru disebabkan oleh Mycobacterium tuberculosis. Gejala umum infeksi jamur paru sama dengan infeksi tuberkulosis ataupun dengan mikroba lainnya. Infeksi jamur paru sering tidak terdiagnosa karena tidak ada gejala yang khas. Infeksi jamur paru sering menyertai penyakit lain sehingga pengobatan terhadap infeksi jamur paru sering terlambat diberikan. Identifikasi kultur konvensional dan dilanjutkan dengan tes biokimia membutuhkan waktu yang lama oleh karena itu diperlukan metode fenotip yang mudah, sederhana dan murah untuk mengidentifikasi antara Candida sp. Tujuan penelitian ini adalah mendeteksi keberadaan jamur dengan metode kultur dari sampel bilasan bronkus dan bilasan lambung. Penelitian ini merupakan penelitian eksperimental untuk mengetahui pertumbuhan jamur Candida sp yang diidolasi dari bilasan lambung dan bronkus suspek tuberculosis yang negatif BTA pada medium Sabaroud Agar Hipertonik. Hasil penelitian ditemukan 100% sampel menunjukkan pertumbuhan Candida sp dari sampel bilasan bronkus dan bilasan lambung tumbuh pada medium SDA Hipertonik 370C dengan rata-rata pertumbuhan 24 jam. Koloni Candida sp yang tumbuh pada medium SDA Hipertonik 370C akan tampak berwarna putih, halus, licin, ukuran koloni dari kecil sampai ukuran besar, jika koloni sudah berumur tua akan berwarna kecoklatan. Candida sp secara mikroskopik berbentuk bulat sampai lonjong dan memiliki pertunasan yang dinamakan budding.