bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between core stability and athletic performance in female university athletes
Authors: De Bruin Marizanne , Coetzee Derik , Schall Robert 
Published: August 2021

Background: Questions remain as to whether core stability represents a single or more components, how to assess core stability, and if a relationship exists with athletic performance in different sport codes.
Objectives: To investigate the relationship between core stability and athletic performance in female university athletes.
Methods: Eighty-three female athletes (hockey, netball, running, soccer and tennis) participated in this quantitative, cross-sectional study. The isometric back extension (IBE), lateral flexion (LF) and abdominal flexion (AF) tests were used to measure core strength and endurance. The core stability grading system using a pressure biofeedback unit was applied to measure core neuromuscular control (NMC). Athletic performance was assessed using the 40 m sprint, T-test, vertical jump (VJ) and the medicine ball chest throw (MBCT). Correlations between the core stability tests and the athletic performance tests were determined, overall and separately by sport. The effect of core stability on athletic performance was analysed using ANCOVA.
Results: Most correlations were weak (r=0.10–0.39), although a very strong correlation was found between LF (strength) and VJ (r=0.90). When considered separately, moderate correlations (r=0.40–0.69) were found between core strength, endurance and motor control with certain athletic performance tests in all five sport codes. In runners, strong correlations (r=0.70–0.89) occurred between AF (endurance) and VJ, and in tennis players between IBE (strength) and the sprint.
Conclusion: Correlations were found between core stability and athletic performance, although most correlations were negligible or weak. Athletic performance in different sport codes is associated with different components of core stability.
Pengaruh Ekstrak Daun Mimba (Azadirachta indica) terhadap Histamin Daging Ikan Tongkol Abu
Authors: Witria Witria , Zainuri Muhammad 
Published: August 2021

Abstrak
Ikan tongkol (Thunnus tonggol) tergolong dalam family scrombidae yang diketahui memiliki kandungan histamin tinggi yang dapat menyebabkan keracunan bagi konsumen. Berbagai upaya dapat dilakukan untuk menurunkan kandungan histamin, salah satunya dengan menggunakan daun mimba (Azadirachta indica). Tujuan penelitian ini adalah untuk menentukan efektivitas pemberian ekstak daun mimba terhadap perkembangan histamin ikan tongkol. Ekstraksi daun mimba menggunakan metode maserasi selama 2 hari. Sampel ikan tongkol berukuran panjang tubuh 30 cm yang didiamkan pada suhu ruang selama 5 jam dijadikan sebagai sampel penelitian ini. Perlakuan yang dibgunakan berupa perendaman ekstrak daun mimba dengan konsentrasi 5%, 25%, dan 50%. Analisis histamin menggunakan perangkat HPLC dan pengolahan data dengan program SPSS. Hasil penelitian menunjukkan kandungan histamin perlakuan kontrol, 5%, 25%, dan 50% secara berurutan sebesar 60,03; 49,63; 50,54; dan 53,81 ppm. Hasil uji SPSS menyatakan bahwa pemberian konsentrasi ekstrak daun mimba sebesar 5% lebih efektif untuk menghambat perkembangan kandungan histamin ikan togkol. Konsentrasi ekstrak daun mimba sebesar 5%, 25%, dan 50% secara berurutan dapat menurunkan kandungan histamin ikan tongkol dengan nilai efektivitas sebesar 17,15%, 15,80%, dan 10,36%.
Ineffective Communication: The Uninformed Injured Worker
Authors: Vanderhooft Jan Eric 
Published: August 2021

Background:
Effective communication has been demonstrated to impact patient health outcomes, specifically in improving symptom resolution, safety, function, and emotional well-being, and to lower malpractice claims. I hypothesized that the communication process with patients with Workers’ Compensation is inadequate.

Methods:
Prospectively, claimants presenting for an independent medical evaluation or an impairment rating were assessed concerning the education that they received with regard to their claim. Basic principles were based on the Utah Labor Commission Employee’s Guide to Workers’ Compensation and an employee information sheet.

Results:
There were 556 consecutive claimants assessed. None of the participants expressed any familiarity with the employee information sheet. Although there was a mean of 12 months since the date of claim to the evaluation, 536 participants (96.4%) were effectively unaware of the principles surrounding their claim; of these participants, 6 had attorneys and 23 had prior industrial claims. Of the 3.6% of participants who had received the State Employee Guide, 5 had a prior evaluation with the medical director of the Labor Commission, 6 had located the information online, and 9 had been provided information by their nurse-case manager. Even with this information, the context or importance of the information was not well understood. There were 16.4% of participants who were aware of the mileage compensation. Two claimants were aware that the insurer, not the employer, was responsible for managing the claim, 2 claimants were aware that their claim was open for life, and 1 claimant was aware that claimants could change physicians.

Conclusions:
Workers’ Compensation programs were designed to expedite care and treatment while decreasing the adversarial environment for workplace injuries. Yet delays and confrontational events continue to be experienced by the injured worker. This often results in the impression that workplace injuries have worse outcomes for the same diagnosis. The lack of effective education with regard to the rights and responsibilities of the claimant may also lead to this poorer outcome. Given studies showing the benefits of patient education in preventing malpractice claims and improving health-care outcomes, it is suggested that improved patient education for the injured worker is warranted and may lead to improved outcomes with diminished adversarial events.
Bacteria-Targeted Fluorescence Imaging of Extracted Osteosynthesis Devices for Rapid Visualization of Fracture-Related Infections
Authors: López-Álvarez Marina , Heuker Marjolein , Sjollema Klaas A. , Dam Gooitzen M. van , Dijl Jan Maarten van , IJpma Frank F.A. , Oosten Marleen van 
Published: August 2021

Abstract
Purpose: Fracture-related infection (FRI) is a serious complication in orthopaedic trauma surgery worldwide. Especially the distinction of infection from sterile inflammation and the detection of low-grade infection are highly challenging. The objective of the present study was to explore the use of bacteria-targeted fluorescence imaging for enhanced detection of FRI on extracted osteosynthesis devices as a step-up towards real-time image-guided trauma surgery.Methods: Extracted osteosynthesis devices from 13 patients, who needed revision surgery after fracture treatment, were incubated with a near-infrared fluorescent tracer composed of the antibiotic vancomycin and the fluorophore IRDye800CW (i.e. vanco-800CW). Subsequently, the devices were imaged and vanco-800CW fluorescence signals were correlated to the results of microbiological culturing and to bacterial growth upon replica plating of the imaged devices on blood agar.Results: Importantly, compared to culturing, the bacteria-targeted fluorescence imaging of extracted osteosynthesis devices with vanco-800CW allows for a prompt diagnosis of FRI, reducing the time-to-result from days to less than 30 min. Moreover, bacteria-targeted imaging will provide surgeons with real-time visual information on the presence and extent of infection.Conclusion: Here we present the first clinical application of fluorescence imaging for detection of FRI. We conclude that imaging with vanco-800CW can provide early, accurate and real-time visual diagnostic information on FRI in the clinical setting, even in case of low-grade infections.
The Application of 3D Printing Technology in the Classification and Preoperative Planning of Complex Tibial Plateau Fractures
Authors: Chen Fuyang , Huang Chenyu , ling chen , Zhou Jinming , Wang Yufeng , Zhang Po , jiang xiao , xu xiaoming , jian jian , Li Jiayi , Wang LIMING , Yao Qingqiang 
Published: August 2021

Abstract
Background: Tibial plateau fracture is one of the common intra-articular fractures in clinic. And its accurate classification and treatment is a difficult problem for orthopedic surgeons. Our research aims to investigate the application value of 3D printing in the classification and preoperative planning of complex tibial plateau fractures.Methods: 28 cases of complex tibial plateau fractures diagnosed and treated in our hospital from January, 2017 to January, 2019.01 were analyzed. Preoperative spiral CT scan was performed and then DICOM data were input into the computer. We use Mimics to process data. And 3D printing technology was applied to print the 3D model of fracture (1:1). Combined with the 3D printed model, the tibial plateau fractures were subdivided into seven types according to the geometric plane of the tibial plateau. The surgical approach was determined on the 3D printed model. And then simulated operations such as accurate reduction of fracture and selection of plate placement were performed.Results: The reconstructed 3D model of tibial plateau fracture can accurately reflect the direction of fracture components displacement and the degree of plateau collapse. Also, it can help with the preoperative reconstructive plan for the tibial plateau fracture. The intraoperative fracture details were basically the same as the 3D printed model. And The fracture surface of the tibial plateau of all 28 patients was well improved in terms of restoring the anatomical structure.Conclusion: 3D printing technology can be used to guide the classification and preoperative planning of complex tibial plateau fractures.
Clinical Study of The Novel Antiseptic Olanexidine Gluconate in Gastrointestinal Cancer Surgery
Authors: Kubo Naoki , Furusawa Norihiko , Takeuchi Daisuke , Imai Shinichiro , Masuo Hitoshi , Umemura Kentaro , Terada Masaru 
Published: August 2021

Abstract
Background

Surgical site infection (SSI) is a common complication of digestive surgery .Olanexidine gluconate (OLG) is a novel developed skin antiseptic and effective against a wide range of bacteria. The purpose of this study is to evaluate the bactericidal efficacy of OLG in gastrointestinal cancer surgery.
Methods

This retrospective study included a total of 281patients who underwent gastrointestinal cancer surgery (stomach or colon). There were two group: 223 patients were treated with OLG (OLG group), and 58 patients were treated with povidone-iodine (PVP-I) (control group). The efficacy and the safety outcomes were measured as the rate of surgical SSI within 30 days after surgery. In addition, we also conducted subgroups defined according to the surgical approach (open or laparoscopic) or primary lesion (stomach or colon).
Results

There was a significant difference in the rate of SSI between the control group and OLG group (10.3% vs. 2.7% ; p = 0.02). There was a significant difference in the SSI rate in superficial infection (8.6% vs. 2.2% ; p = 0.0345) but not in deep infection (1.7% vs. 0.5% ; p = 0.371). There was no significant difference between the control group and OLG group in the overall rate of adverse skin reaction (5.2% vs. 1.8% ; p = 0.157).
Conclusion

This retrospective study demonstrates that OLG is more effective than PVP-I for preventing SSI during gastrointestinal cancer surgery.
FPGA Based Hardware Abstraction of Quantum Computing System
Authors: Khalid Madiha , MUHAMMAD Najam ul Islam , Khokhar Umar Mujahid , Jafri Atif , Choi Hongsik 
Published: August 2021

Abstract
The number of transistors per unit area are increasing every year by virtue of Moore’s law. It is estimated that the current rate of evolution in the field of chip design will reduce the transistor to atomic scale by 2024. At atomic level the quantum mechanical characteristics dominate, affecting the ability of transistors to store information in the form of bits. The quantum computers have been proposed as one way to effectively deal with this predicament. The quantum computing circuits utilize the spinning characteristics of electron to store information. This paper describes a proposition of resource efficient FPGA based quantum circuit abstraction. A non-programmable embedded system capable of storing, introducing a phase shift in the qubit and its measurement is implemented. The main objective of the proposed abstraction is to provide a FPGA based platform comprising of fundamental sub blocks for designing quantum circuits. A primary quantum key distribution algorithm i.e BB84 is implemented on the proposed platform as a proof of concept. The distinguishing feature of the proposed design is the flexibility to enhance the quantum circuit emulation accuracy at the cost of computational resources. The proposed emulation exhibits two principal properties of the quantum computing i.e. parallelism and probabilistic measurement.
Olanzapine (5 mg) Plus Standard Triple Antiemetic Therapy for the Prevention of Multiple-Day Cisplatin Chemotherapy-Induced Nausea and Vomiting: A Prospective Randomized Controlled Study
Authors: Gao Jiali , Zhao Jun , Jiang Caihong , Chen Feng , Zhao Lanzhen , Jiang Ying , Li Hui , Wang Wenjuan , Wu Yungaowa , Jin Yilan , Da Lenggaowa , Liu Guang , Zhang Yajuan , Li Hongxia , Zhang Zewei , Jin Gaowa , Li Quanfu 
Published: August 2021

Abstract
Objective A prospective randomized controlled trial was conducted to compare 5 mg olanzapine plus standard triple antiemetic therapy for the prevention of nausea and vomiting induced by multiple-day cisplatin chemotherapy. Methods Patients received 3-day cisplatin-based chemotherapy(25mg/m2/d) were given either 5mg olanzapine quadruple therapy (aprepitant, tropisetron, dexamethasone) or 5mg olanzapine-based triplet therapy. The primary end-point was the complete response(CR) in the overall phase(OP)(0-120h) between quadruple regimen group and triplet regimen group. The secondary end-points were the CR in the acute phase(AP)(0-24h), delayed phase(DP)(25-120h) between two groups. The first time of vomiting was also compared by Kaplan-Meier curves. The impact of chemotherapy induced nausea and vomiting(CINV) on the quality of life was assessed by the Functional Living Index-Emesis(FLIE). Aprepitant-related adverse effects (AEs) was also recorded. Results (1) The primary end-point CR during overall phase was 76.0% (45/59) vs 67.0% (41/61) between the quadruple regimen group and triplet regimen group(P =0.271). The secondary end-point CR during the AP was significantly higher in the quadruple group than in the triple group, which was 100.0%(59/59) vs 93.0%(57/61)(P=0.045). The difference between the groups was especially greater in the delayed phase(quadruple group 76.0% (45/59) vs triple group 67.0%(41/61)(P=0.271)). The rate of patients who achieved total protection in the overall phase was also larger in the quadruple group than in the triple group(28.8% (17/59) vs 23.0%(14/61)(P=0.463)). During the OP, the incidence of no vomiting in quadruple group and triple group was 93.2%(55/59) vs 80.3%(49/61)(P=0.038)respectively.(2) Kaplan-Meier curves of time to first emesis were obviously longer in the quadruple group than in the triple group(P=0.031). According to FLIE, no impact of CINV on daily life was defined as total score of questionnaire >108, this study exhibited identical life quality in quadruple group and the triplet group.(3) The most common aprepitant- and olanzapine-related AEs included sedation, fatigue and constipation. The occurrences between two groups were identical. Conclusion It may been recommended that combined 5mg olanzapine with aprepitant, tropisetron, dexamethasone quadruple therapy for the prevention of multiple-day cisplatin induced nausea and vomiting due to the better CINV control rate and safety.
Evaluating Anti-Inflammatory Potential of Etodolac Co-Crystals: Nitric Oxide, IL-6 And TNF-a As Potential Markers
Authors: Parashar Poonam , Gautam Shalini , Singh Neelu , Kanoujia Jovita , Yadav Abhishek , Singh Indu , Dwivedi Monika , Saraf Shubhini A 
Published: August 2021

Abstract
The present investigation deals with solubility enhancement of Etodolac (ETD) through co-crystals technique utilizing various co-formers and to evaluate their therapeutic efficacy against carrageenan-induced inflammation. Co-formers citric acid anhydrous and tartaric acid were selected to formulate ETD co-crystals to improve solubility and dissolution employing neat grinding technique. The prepared co-crystals were characterized for solubility enhancement, Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), powder X-ray diffraction (PXRD), in vitro dissolution and stability studies. The co-crystals were further investigated for in vivo studies to assess their potential to cure paw edema in mice. The outcome of the study illustrated significantly improved solubility and dissolution of ETD up to 6.15 folds using citric acid. Approximately a two-fold reduction in nitric oxide and cytokines levels was observed with optimized formulation. Also, substantial inhibition of inflammation was observed in paw edema induced animals. In sight of the above results the co-crystal approach could be an alternative for enhanced therapeutic potential.
Identification of Possible Inhibitors of SARS-CoV-2 Main Protease from some Bioactive Compounds of Artemisia annua: An in silico Approach
Authors: Johnson Titilayo Omolara , Adegboyega Abayomi Emmanuel , Ojo Oluwafemi Adeleke , Yusuf Amina Jega , Iwaloye Opeyemi , Ugwah-Oguejiofor Chinenye Jane , Asomadu Rita Onyekachukwu , Chukwuma Ifeoma Felicia , Ejembi Stephen Adakole , Ugwuja Emmanuel Ike 
Published: August 2021

Abstract
The inhibitory potential of Artemisia annua, a well-known antimalarial herb, against several viruses including the coronavirus is increasingly gaining recognition. The plant extract has shown significant activity against both the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the novel SARS-CoV-2, that is currently ravaging the world. It is therefore necessary to identify the bioactive compounds of the plants that are responsible for this activity, for the purpose of designing drugs against SARS-CoV-2. In this study, we employed in silico techniques comprising of molecular docking, binding free energy calculations, pharmacophore modelling as well as druglikeness, pharmacokinetics and toxicity predictions, to identify potential inhibitors of the SARS-CoV-2 main protease (Mpro) from 168 bioactive compounds of Artemisia annua. Rhamnocitrin, Isokaempferide, Kaempferol, Quercimeritrin, Apigenin, Penduletin, Isoquercitrin, Astragalin, Luteolin-7-glucoside and Isorhamnetin were ranked highest; with docking scores ranging from -7.84 to -7.15 kcal/mol compared with -6.59 kcal/mol demonstrated by the standard ligand. Rhamnocitrin, Isokaempferide and Kaempferol, like the standard ligand interacted with important active site amino acid residues like HIS 41, CYS 145, ASN 142, and GLU 166, among others. These compounds also possess acceptable druglike properties and safety profile. Hence, they could be considered for experimental studies and further development into drugs against SARS-CoV-2.
Anaerobic Biofilm Enriched With an Ammonia Tolerant Methanogenic Consortium to Improve Wastewater Treatment in The Fishing Industry
Authors: Alarcon Manuel , Ruiz-Tagle Nathaly , Gonzalez Fidelina , Jopia-Contreras Paz , Aspé Estrella , Urrutia Homero , Sossa Katherine 
Published: August 2021

Abstract
The digestion efficiency of liquid industrial wastes increases when using bioreactors colonized by microbial biofilms. High concentrations of proteins derived from the fish processing industry lead to the production of ammonia, which inhibits methane production. Two bioreactors were constructed to compare methanogenic activity: one enriched with mMPA consortia (control bioreactor), and the second with NH3 tolerant consortia (treatment bioreactor). Ammonia tolerant activity was assessed by applying an ammonia shock (755 mg NH3/L). Methane production, consumption of total organic carbon (TOC) and the taxonomic composition of bacteria and archaea was evaluated using 16S rDNA in the acclimatization, ammonia shock, and recovery phases. The ammonia shock significantly affected both methane production and the consumption of TOC in the control reactor (p<0.05) and taxonomical composition of the microbial consortia (OTU). These values remained constant in the treatment reactor. The analysis of biofilm composition showed a predominance of Methanosarcinaceae (Methanomethylovorans sp., and probably two different species of Methanosarcina sp.) in bioreactors. These results demonstrate that using acclimated biofilms enriched with ammonia tolerant methanogens control the inhibitory effect of ammonia on methanogenesis.
WITHDRAWN: Chemical Modification of Nisin With Homocysteine Thiolactone And Its Antibacterial Activity
Authors: Özer Ezgi Demir , YILDIRIM Metin 
Published: August 2021

Abstract
The objective of this study was to prepare N-homocysteine conjugate of nisin, and to evaluate the effect of N-homocysteinylation reaction on the antibacterial activity of nisin. Progression of the modification was monitored by measuring free sulfhydryl groups, and by using both acetic acid urea polyacrylamide gel electrophoresis (AAU-PAGE) and tricine sodium dodecyl sulphate polyacrylamide gel electrophoresis (tricine SDS-PAGE). Optimum conditions to attain the maximum N-homocysteinylation degree (6.30%) were determined as 6 mg/mL nisin, 150 mM homocysteine thiolactone, 150 rpm shaker speed, 3.0 pH and 6 hrs reaction time. Antibacterial activity of N-homocysteinylated nisin was determined against Staphylococcus aureus ATCC 6538, Bacillus subtilis ATCC 6633, Lactococcus lactis ssp. cremoris AÜ, Enterococcus faecium ATCC 9097, Listeria monocytogenes NCTC 5348 and Escherichia coli RSKK. Of all the bacteria tested only the growth of E. faecium was inhibited slightly by modified nisin having just about 10% of antibacterial activity of unmodified nisin. Tricine SDS-PAGE analysis applied after trypsin and thermolysin hydrolysis showed that side chains of Lys12 and Lys22 were both modified with homocysteine thiolactone reaction.
A Green Energy Research: Forecasting of Wind Power For A Cleaner Environment Using Robust Hybrid Metaheuristic Model
Authors: Kerem Alper , Saygin Ali , Rahmani Rasoul 
Published: August 2021

Abstract
Wind is a stochastic and intermittent renewable energy source. Due to it’s nature, it is extremely hard to forecasting of wind power. Accurate wind power forecasting can be encouraging and motivating for investors to shed light on future uncertainties caused by global warming. Thus, CO2 and other greenhouse gases which are harmful to the environment will not be released into the atmosphere, while generating electrical energy. This paper presents a novel precise, fast and powerful hybrid metaheuristic wind power forecasting approach based on statistical and mathematical data from real weather stations. The model was developed as a hybrid metaheuristic algorithm based on Artificial Neural Networks (ANNs), Particle Swarm Optimization (PSO) and Radial Movement Optimization (RMO). Real-time wind data was gathered from Wind Measuring Stations (WMS) at two separate places in Burdur and Osmaniye cities, Turkey. The key contribution of this new model is the ability to perform wind power forecasting studies, without needing wind speed data, with high accuracy and rapid solutions. Also, it has been carried out wind power forecasting studies with high accuracy despite the height differences between the sensors. That is, for WMS-1 and WMS-2, it has succeeded the wind power forecasting at 61m and 60.3m using temperature (3m), humidity (3m), and pressure (3.5m) data. The performance results were presented in tables and graphs.