Reduced engagement of visual attention in children with autism spectrum disorder
Authors: McLaughlin Christopher S , Grosman Hannah E , Guillory Sylvia B , Isenstein Emily L , Wilkinson Emma , Trelles Maria del Pilar , Halpern Danielle B , Siper Paige M , Kolevzon Alexander , Buxbaum Joseph D , Wang A Ting , Foss-Feig Jennifer H 
Published: May 2021

A common example of social differences in autism spectrum disorder is poor modulation of reciprocal gaze, including reduced duration of eye contact and difficulty detecting the aim of another’s gaze. It remains unclear, however, whether such differences are specific to the social domain, or are instead indicative of broader alterations in processes of visual engagement and disengagement in autism spectrum disorder. To assess whether children with autism spectrum disorder experience altered engagement of visual attention, and whether such processes are specific to social stimuli, we implemented a gap-overlap eye-tracking paradigm consisting of both social and nonsocial images with children with autism spectrum disorder ( n = 35) and typical development ( n = 32). Children with autism spectrum disorder demonstrated a significantly reduced overall gap effect (i.e. difference in saccade latency to peripheral stimuli between overlap and gap trials) compared with the controls. This reduction spanned both social and nonsocial conditions. Our findings suggest that children with autism spectrum disorder experience alterations in general processes of engagement of visual attention, and that these alterations are not specific to the social domain, but do associate with cognitive functioning. Affected processes of visual engagement in autism spectrum disorder may contribute to features like poor reciprocal gaze, but social-specific symptoms of autism spectrum disorder likely originate from other subcortical processes or higher order cognition. Lay abstract Limited eye contact and difficulty tracking where others are looking are common in people with autism spectrum disorder. It is unclear, however, whether these are specifically social differences; it is possible that they are a result of broader alterations in engaging and disengaging visual attention. We used eye-tracking technology with children with autism spectrum disorder ( n = 35) and typical development ( n = 32), showing them both social and nonsocial imaging to test their visual attention. Children with autism spectrum disorder had a significant difference in how long it took them to look from an image in the middle to one on the side, depending on whether the middle image stayed on the screen or flashed off before the one on the side appeared. This difference was present for both social and nonsocial images, and was related to cognitive ability for only the children with autism spectrum disorder. Our findings suggest that children with autism spectrum disorder have differences in general processes of engaging visual attention that are not specifically social in nature, and that these processes may relate to cognitive ability in autism spectrum disorder. Affected processes of visual engagement in autism spectrum disorder may contribute to symptoms like reduced eye contact, but social-specific symptoms of autism spectrum disorder likely do not stem from reduced visual engagement alone.