bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gambaran Tingkat Pengetahuan Remaja Tentang Seks Bebas Pada Masa Pademi COVID-19 di SMP Negeri 4 Pupuan
Authors: Ariyanti Kadek Sri 
Published: September 2021

Latar belakang: Seks bebas bebas merupakan salah satu permasalahan remaja yang harus mendapat perhatian yang khusus. Tingginya angka seks bebas pada remaja dipengaruhi oleh berbagai faktor, salah satunya adalah pengetahuan yang kurang terkait seks bebas.
Tujuan: Penelitian ini bertujuan untuk mengetahui gambaran tingkat pengetahuan remaja tentang seks bebas di SMP Negeri 4 Pupuan.
Metode: Jenis penelitian ini adalah deskriptif dengan rancangan cross sectional. Jumlah populasi sebanyak 299 orang siswa, sampel dalam penelitian ini berjumlah 171 orang, pengambilan sampel dengan cara random sampling , uji statistik menggunakan SPSS. Instrumen dalam penelitian ini menggunakan kuesioner yang disebarkan secara online melalui google form. Analisa data dengan cara deskriptif untuk memperoleh distribusi frekuensi variabel.
Hasil: Dari hasil penelitian diperoleh tingkat pengetahuan remaja tentang seks bebas dalam kategori cukup baik yaitu sebanyak 75%.
Rekomendasi: Sekolah diharapkan untuk meningkatkan kegiatan ekstrakurikuler yang terkait dengan kesehatan reproduksi remaja untuk meningkatkan pengetahuan siswa.

Kata kunci: Pengetahuan, Remaja, Seks Bebas.
Gambaran Peran Kader Kesehatan dalam Menyukseskan Program KB Pada Masa Pandemi Covid-19 di Wilayah Kerja Puskesmas Marga I
Authors: Ariyanti Kadek Sri 
Published: September 2021

Latar belakang: Kondisi pandemi menimbulkan kekhawatiran adanya lonjakan kelahiran bayi atau baby boom pasca pandemi Covid-19. Peran kader kesehatan dalam menyukseskan program KB dalam situasi ini sangat diperlukan, mengingat kecemasan masyarakat untuk datang ke tempat layanan kesehatan cukup tinggi.
Tujuan: Penelitian ini bertujuan untuk mengetahui gambaran peran kader kesehatan dalam menyukseskan program KB pada masa Pandemi Covid-19 di Wilayah Kerja Puskesmas Marga I.
Metode: Jenis penelitian ini adalah deskriptif dengan rancangan cross sectional. Populasi dalam penelitian ini adalah kader kesehatan di Wilayah Kerja Puskesmas Marga I dengan jumlah 125 orang. Sampel berjumlah 124 orang yang diambil dengan teknik total sampling. Instrumen dalam penelitian ini menggunakan kuesioner yang disebarkan secara online melalui google form. Analisa data dengan cara deskriptif untuk memperoleh distribusi frekwensi variabel.
Hasil dan Kesimpulan: Dari hasil penelitian diperoleh bahwa kader kesehatan yang memberikan informasi tentang KB sebanyak 67%. Informasi yang diberikan sebagian besar melalui whatsapp yaitu sebesar 63%. Sebagian kecil kader memberikan informasi melalui leaflet/brosur (43%) dan melakukan kunjungan rumah (40%).
Rekomendasi: Kader lebih gencar memberikan informasi tentang KB pada masa pandemi Covid-19 sebagai upaya untuk menyukseskan program KB di Indonesia.
Identification and validation of hub genes for diabetic retinopathy
Authors: Peng Li , Ma Wei , Xie Qing , Chen Baihua 
Published: September 2021

Background
Diabetic retinopathy (DR) is characterized by a gradually progressive alteration in the retinal microvasculature that leads to middle-aged adult acquired persistent blindness. Limited research has been conducted on DR pathogenesis at the gene level. Thus, we aimed to reveal novel key genes that might be associated with DR formation via a bioinformatics analysis.

Methods
The GSE53257 dataset from the Gene Expression Omnibus was downloaded for gene co-expression analysis. We identified significant gene modules via the Weighted Gene Co-expression Network Analysis, which was conducted by the Protein-Protein Interaction (PPI) Network via Cytoscape and from this we screened for key genes and gene sets for particular functional and pathway-specific enrichments. The hub gene expression was verified by real-time PCR in DR rats modeling and an external database.

Results
Two significant gene modules were identified. Significant key genes were predominantly associated with mitochondrial function, fatty acid oxidation and oxidative stress. Among all key genes analyzed, six up-regulated genes (i.e., SLC25A33, NDUFS1, MRPS23, CYB5R1, MECR, and MRPL15) were highly and significantly relevant in the context of DR formation. The PCR results showed that SLC25A33 and NDUFS1 expression were increased in DR rats modeling group.

Conclusion
Gene co-expression network analysis highlights the importance of mitochondria and oxidative stress in the pathophysiology of DR. DR co-expressing gene module was constructed and key genes were identified, and both SLC25A33 and NDUFS1 may serve as potential biomarker and therapeutic target for DR.
Identification of Children with Disabilities in Government Primary Schools of Hyderabad District - Survey
Authors: Jyothi V. Ananda 
Published: September 2021

Disability can be defined as any limitation or restriction to perform developmentally appropriate activities which are desired by society. The International Classification of Functioning, Disability and Health: Children and Youth Version (ICF-CY) defined disability as, “neither purely biological nor social but instead the interaction between health conditions, environmental and personal factors.” It described disability at three levels: 1. An impairment in body function or structure, such as a cataract which prevents the passage of light and sensing of form, shape, and size of visual stimuli;, 2. A limitation in activity, such as the inability to read or move around; 3. A restriction in participation, such as exclusion from school. Children with disabilities require interventions and support, Difficulty in oral language 1. Slow development in speaking words or sentences (also referred to as,late talkers) 2. Pronunciation problems 3. Difficulty learning new words; slow vocabulary growth 4. Difficulty finding the right word to use when speaking 5. Difficulty understanding and following simple (one-step) directions 6. Difficulty understanding questions 7. Difficulty recognizing or learning rhyming words 8. Lack of interest in storytelling.
Students with learning disabilities are among the most vulnerable-at chronic risk for "not learning" under the aforementioned conditions, for long-term academic and social problems, and for lifelong debilitating side-effects of their classroom experiences. 30 Government Primary schools from class 1 to 5 were identified in Hyderabad district and 3200 children were screened to identify whether they have hearing and speech impairment, Intellectual Disability, Autism, Attention Deficit Hyperactivity Disorder and learning Ethical norms were followed in this study for collecting the data. Care has been taken to meet the ethical requirements in this research study, during developing the screening camp while discussion with the teachers and children. Out of 3200 children 660 children were identified with different disabilities and referred to the concerned Institutes for detailed evaluation and intervention services. There is an urgent and substantial need to identify as early as possible those young children in need of services. The need for early identification of learning disabilities is highly related to potential.
Influence of Pre and Post Emergence Herbicides on Weed Dynamics, WCE and Yield of Pigeon Pea under Rainfed Conditions
Authors: Nimbargi Yusufali A. , Mavarkar Narayan S. , Rathod Pandit S. , Ganapathi . , Nandish M. S. 
Published: September 2021

A field experiment was conducted at ICAR-KVK, Kalaburgi, during Kharif seasons of 2018-19 and 2019-20 to adjudge the efficacy of pre and post emergence herbicides against diverse weed flora in pigeonpea ecosystem. The experiment was laid out in RCBD with 11 treatments comprising of different pre-emergent herbicides viz., Pendimethalin, Pendimethalin 30 EC + Imazethapyr 2 EC and post-emergence premix product herbicides such as Imazamox 35 WG + Imazethapyr 35 WG, Propaquizafop 2.5% + Imazethapyr 3.75%w/w ME and their different dosages with cultural methods were compared with weed free check and weedy check treatments. Among the different pre and post emeregent herbicides tested against different weed flora, post emergent application of Propaquizafop 2.5% + Imazethapyr 3.75% w/w ME @ 2000 ml ha-1 at 20-25 days recorded significantly lower weed density, weed dry weight, highest weed control efficiency (91.36%) and lowest weed index (8.78%) and higher grain yield (1209 kg ha-1 ), net returns (` 43,036 ha-1) and benefit cost ratio (2.35) followed by Propaquizafop 2.5% + Imazethapyr 3.75% w/w ME @ 1500 ml ha-1 at 20-25 DAS, Imazamox 35 WG + Imazethapyr 35 WG at 100 g ha-1 at 20-25 DAS and HW at 20 and IC 40 and 60 DAS.
An Evaluation on Sealing Ability of Calcium Silicate-Based Cements and Glass Ionomer Cement as Perforation Repair Materials
Authors: Shivakumar Vanishree H. , Tegginamani Anand S. , Dicksit Daniel Devaprakash , Zamzuri Ahmad Termizi B 
Published: September 2021

Aims: The study evaluated the sealing ability of Biodentine, MTA Repair HP, and Glass ionomer cement as perforation repair materials by using a Stereomicroscopic analysis.
Study Design: Experimental in vitro study
Methodology: The access cavity was prepared on 45 samples of maxillary and mandibular teeth with a perforation of the standardized diameter of a No. 2 round bur at the bottom of the pulp chamber. All 45 samples were divided into three different experimental groups of 15 samples each. Group A (n=15), Group B (n=15) and Group C (n=15). The furcation repairs of the samples in groups A, B and C were carried out using Biodentine, MTA Repair HP and glass ionomer cement respectively. All sealed furcation perforation samples were stored at room temperature for 24 hours. Two layers of nail varnish were coated on all the surfaces to avoid dye penetration except for 2 mm around the area of the perforation site. After complete drying, all specimens were separately soaked in 2% methylene blue solution for 48 hours, cleaned with water and dried for 24 hours. They were sectioned buccolingually. The perforation wall of the sectioned sample with the greatest dye penetration was selected for microleakage analysis.
Results: The collected data from the three experimental groups were subjected to statistical analysis using one-way analysis of variance and Tukey's post hoc test for multiple comparisons of mean differences in dye penetration. The Biodentine group had the significantly lowest dye penetration length compared with the MTA Repair HP and glass ionomer cement groups (P<0.001).
Conclusion: Biodentine showed better sealing ability as a repair material for furcation perforations compared to the other two materials.
Synergistic Manipulation of Zn2+ Ion Flux and Nucleation Induction Effect Enabled by 3D Hollow SiO2/TiO2/Carbon Fiber for Long‐Lifespan and Dendrite‐Free Zn–Metal Composite Anodes
Authors: Xue Pan , Guo Can , Wang Nanyang , Zhu Kaiping , Jing Shuang , Kong Shuo , Zhang Xiaojie , Li Li , Li Hongpeng , Feng Yongbao , Gong Wenbin , Li Qiulong 
Published: September 2021

AbstractAqueous rechargeable zinc–metal batteries are a promising candidate for next‐generation energy storage devices due to their intrinsic high capacity, low cost, and high safety. However, uncontrollable dendrite formation is a serious problem, resulting in limited lifespan and poor coulombic efficiency of zinc–metal anodes. To address these issues, a 3D porous hollow fiber scaffold with well‐dispersed TiO2, SiO2, and carbon is used as superzincophilic host materials for zinc anodes. The amorphous TiO2 and SiO2 allow for controllable nucleation and deposition of metal Zn inside the porous hollow fiber even at ultrahigh current densities. Furthermore, the as‐fabricated interconnected conductive hollow SiO2 and TiO2 fiber (HSTF) possess high porosity, high conductivity, and fast ion transport. Meanwhile, the HSTF exhibits remarkable mechanical strength to sustain massive Zn loading during repeated cycles of plating/stripping. The HSTF with interconnected conductive network can build a uniform electric field, redistributing the Zn2+ ion flux and resulting in smooth and stable Zn deposition. As a result, in symmetrical cells, the Zn@HSTF electrode delivers a long cycle life of over 2000 cycles at 20 mA cm−2 with low overpotential (≈160 mV). The excellent cycling lifespan and low polarization are also realized in Zn@HSTF//MnO2 full cells.
A Shape‐Variable, Low‐Temperature Liquid Metal–Conductive Polymer Aqueous Secondary Battery
Authors: Fu Hao , Liu Guicheng , Xiong Lingyun , Wang Manxiang , Lee Jeongwoo , Ren Ren , Yang Woochul , Lee Joong Kee 
Published: September 2021

AbstractA shape‐variable aqueous secondary battery operating at low temperature is developed using Ga68In22Sn10 (wt%) as a liquid metal anode and a conductive polymer (polyaniline (PANI)) cathode. In the GaInSn alloy anode, Ga is the active component, while Sn and In increase the acid resistance and decrease the eutectic point to ‐19 °C. This enables the use of strongly acidic aqueous electrolytes (here, pH 0.9), thereby improving the activity and stability of the PANI cathode. Consequently, the battery exhibits excellent electrochemical performance and mechanical stability. The GaInSn–PANI battery operates via a hybrid mechanism of Ga3+ stripping/plating and Cl− insertion/extraction and delivers a high reversible capacity of over 223.9 mAh g−1 and an 80.3% retention rate at 0.2 A g−1 after 500 cycles, as well as outstanding power and energy densities of 4300 mW g−1 and 98.7 mWh g−1, respectively. Because of the liquid anode, the battery without packaging can be deformed with a small force of several millinewtons without any capacity loss. Moreover, at approximately ‐5 °C, the battery delivers a capacity of 67.8 mAh g−1 at 0.2 A g−1 with 100% elasticity. Thus, the battery is promising as a deformable energy device at low temperatures and in demanding environments.
Miniaturized VIS‐NIR Spectrometers Based on Narrowband and Tunable Transmission Cavity Organic Photodetectors with Ultrahigh Specific Detectivity above 1014 Jones
Authors: Xing Shen , Nikolis Vasileios Christos , Kublitski Jonas , Guo Erjuan , Jia Xiangkun , Wang Yazhong , Spoltore Donato , Vandewal Koen , Kleemann Hans , Benduhn Johannes , Leo Karl 
Published: September 2021

AbstractSpectroscopic photodetection plays a key role in many emerging applications such as context‐aware optical sensing, wearable biometric monitoring, and biomedical imaging. Photodetectors based on organic semiconductors open many new possibilities in this field. However, ease of processing, tailorable optoelectronic properties, and sensitivity for faint light are still significant challenges. Here, the authors report a novel concept for a tunable spectral detector by combining an innovative transmission cavity structure with organic absorbers to yield narrowband organic photodetection in the wavelength range of 400–1100 nm, fabricated in a full‐vacuum process. Benefiting from this strategy, one of the best performed narrowband organic photodetectors is achieved with a finely wavelength‐selective photoresponse (full‐width‐at‐half‐maximum of ≈40 nm), ultrahigh specific detectivity above 1014 Jones, the maximum response speed of 555 kHz, and a large dynamic range up to 168 dB. Particularly, an array of transmission cavity organic photodetectors is monolithically integrated on a small substrate to showcase a miniaturized spectrometer application, and a true proof‐of‐concept transmission spectrum measurement is successfully demonstrated. The excellent performance, the simple device fabrication as well as the possibility of high integration of this new concept challenge state‐of‐the‐art low‐noise silicon photodetectors and will mature the spectroscopic photodetection into technological realities.
Robust Jumping Actuator with a Shrimp‐Shell Architecture
Authors: Yu Kaiqing , Ji Xiaozhou , Yuan Tianyu , Cheng Yao , Li Jingjing , Hu Xiaoyu , Liu Zunfeng , Zhou Xiang , Fang Lei 
Published: September 2021

AbstractIt is highly desirable to develop compact‐ and robust‐film jumping robots that can withstand severe conditions. Besides, the demands for strong actuation force, large bending curvature in a short response time, and good environmental tolerance are significant challenges to the material design. To address these challenges, this paper reports the fabrication of a thin‐film jumping actuator, which exhibits a shrimp‐shell architecture, from a conjugated ladder polymer (cLP) that is connected by carbon nanotube (CNT) sheets. The hierarchical porous structure ensures the fast absorption and desorption of organic vapor, thereby achieving a high response rate. The actuator does not exhibit shape distortion at temperatures of up to 225 °C and in concentrated sulfuric acid, as well as when immersed in many organic solvents. This work avails a new design strategy for high‐performance actuators that function under harsh and complicated conditions.
Enhanced Charge Collection in Non‐Fullerene Organic Solar Cells Using Iridium Complex as an Electron Extraction Layer
Authors: Zhou Pengchao , Liu Yuling , Gu Jialu , Lian Hong , Lan Weixia , Liao Yingjie , Pu Huayan , Wei Bin 
Published: September 2021

AbstractUltrathin iridium (Ir) complexes (e.g., bis[2‐(4,6‐difluorophenyl)pyridinato‐C2,N](picolinato)iridium(III) (FIrpic)) are first introduced as electron extraction layers (EELs) in non‐fullerene organic photovoltaics (OPVs), and a set of devices based on non‐fullerene materials is fabricated. It is demonstrated that this approach can rationally enhance the corresponding short current density and open circuit voltage and finally improve the photovoltaic performance of OPVs. Furthermore, optimized bilayer EELs using combined FIrpic and 8‐hydroxyquinoline lithium (Liq) are investigated. The resulting device presents excellent power conversion efficiency (PCE) of 15.85%, which is much higher than that of control device without FIrpic layer (14.6%). Moreover, Ir complexes show great universality when combined with other materials serving as EELs. This may provide an extra direction for further enhancement of OPVs performance.
Reproductive one health in primates
Authors: Moresco Anneke , Feltrer‐Rambaud Yedra , Wolfman Darcy , Agnew Dalen W. 
Published: September 2021

AbstractOne Health is a collaborative trans‐disciplinary approach to health; integrating human, animal, and environmental health. The focus is often on infection disease transmission and disease risk mitigation. However, One Health also includes the multidisciplinary and comparative approach to disease investigation and health of humans, animals, and the environment. One key aspect of environmental/ecosystem health is conservation, the maintenance of healthy, actively reproducing wildlife populations. Reproduction and reproductive health are an integral part of the One Health approach: the comparative aspects of reproduction can inform conservation policies or breeding strategies (in situ and ex situ) in addition to physiology and disease. Differences in reproductive strategies affect the impact poaching and habitat disruption might have on a given population, as well as ex situ breeding programs and the management of zoo and sanctuary populations. Much is known about chimpanzees, macaques, and marmosets as these are common animal models, but there is much that remains unknown regarding reproduction in many other primates. Examining the similarities and differences between and within taxonomic groups allows reasonable extrapolation for decision‐making when there are knowledge gaps. For example: (1) knowing that a species has very low reproductive rates adds urgency to conservation policy for that region or species; (2) identifying species with short or absent lactation anestrus allows ex situ institutions to better plan contraception options for specific individuals or prepare for the immediate next pregnancy; (3) recognizing that progestin contraceptives are effective contraceptives, but may be associated with endometrial hyperplasia in some species (inLemuridaebut not great apes) better guides empirical contraceptive choice; (4) recognizing the variable endometriosis prevalence across taxa improves preventive medicine programs. A summary of anatomical variation, endocrinology, contraception, pathology, and diagnostics is provided to illustrate these features and aid in routine physical and postmortem examinations as well as primate management.
Thalamic Influence on Slow Wave Slope Renormalization During Sleep
Authors: Jaramillo Valeria , Jendoubi Jasmine , Maric Angelina , Mensen Armand , Heyse Natalie C. , Eberhard‐Moscicka Aleksandra K. , Wiest Roland , Bassetti Claudio L. A. , Huber Reto 
Published: September 2021

ObjectiveSlow waves are thought to mediate an overall reduction in synaptic strength during sleep. The specific contribution of the thalamus to this so‐called synaptic renormalization is unknown. Thalamic stroke is associated with daytime sleepiness, along with changes to sleep electroencephalography and cognition, making it a unique “experiment of nature” to assess the relationship between sleep rhythms, synaptic renormalization, and daytime functions.MethodsSleep was studied by polysomnography and high‐density electroencephalography over 17 nights in patients with thalamic (n = 12) and 15 nights in patients with extrathalamic (n = 11) stroke. Sleep electroencephalographic overnight slow wave slope changes and their relationship with subjective daytime sleepiness, cognition, and other functional tests were assessed.ResultsThalamic and extrathalamic patients did not differ in terms of age, sleep duration, or apnea–hypopnea index. Conversely, overnight slope changes were reduced in a large cluster of electrodes in thalamic compared to extrathalamic stroke patients. This reduction was related to increased daytime sleepiness. No significant differences were found in other functional tests between the 2 groups.InterpretationIn patients with thalamic stroke, a reduction in overnight slow wave slope change and increased daytime sleepiness was found. Sleep‐ and wake‐centered mechanisms for this relationship are discussed. Overall, this study suggests a central role of the thalamus in synaptic renormalization. ANN NEUROL 2021;90:821–833