bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect on healing rates of wounds treated with direct cold atmospheric plasma: a case series
Authors: Ernst Jennifer , Tanyeli Murat , Borchardt Thomas , Ojugo Moses , Helmke Andreas , Viöl Wolfgang , Schilling Arndt F , Felmerer Gunther 
Published: November 2021

Objective: The response of different critical acute and hard-to-heal wounds to an innovative wound care modality—direct application of cold atmospheric plasma (CAP)—was investigated in this clinical case series. Method: Over an observation period of two years, acute wounds with at least one risk factor for chronification, as well as hard-to-heal wounds were treated for 180 seconds three times per week with CAP. CAP treatment was additional to standard wound care. Photographs were taken for wound documentation. The wound sizes before the first CAP treatment, after four weeks, after 12 weeks and at wound closure/end of observation time were determined using image processing software, and analysed longitudinally for the development of wound size. Results: A total of 27 wounds (19 hard-to-heal and eight acute wounds) with a mean wound area of 15cm2 and a mean wound age of 49 months were treated with CAP and analysed. All (100%) of the acute wounds and 68% of the hard-to-heal wounds healed after an average treatment duration of 14.2 weeks. At the end of the observation period, 21% of hard-to-heal wounds were not yet closed but were reduced in size by >80%. In 11% of the hard-to-heal wounds (n=2) therapy failed. Conclusion: The results suggested a beneficial effect of additional CAP therapy on wound healing. Declaration of interest: This work was carried out within the research projects ‘Plasma for Life’ (funding reference no. 13FH6I04IA) with financial support from the German Federal Ministry of Education and Research (BMBF). In the past seven years AFS has provided consulting services to Evonik and has received institutional support by Heraeus, Johnson & Johnson and Evonik. There are no royalties to disclose. The Department for Trauma Surgery, Orthopaedics and Plastic Surgery received charitable donations by CINOGY GmbH. CINOGY GmbH released the di_CAP devices and electrodes for the study. WV and AH were involved in the development of the used di_CAP device (Plasmaderm, CINOGY GmbH). WV is shareholder of the outsourced start-up company CINOGY GmbH.
Telemedicine versus face-to-face care for treatment of patients with lower extremity ulcers
Authors: Gamus Alexander , Keren Elad , Kaufman Hanna , Brandin Gila , Peles Daniel , Chodick Gabriel 
Published: November 2021

Objective: Lower extremity ulcers (LEUs) are associated with a decline in patients' quality of life (QoL). Better healthcare availability in remote regions, facilitated by telemedicine (TM), may improve patient wellbeing. The aim of this study was to compare the QoL of patients treated via synchronous video TM with that of patients treated with standard face-to-face (FTF) care. Method: The study was performed in a large health services provider in Israel (Maccabi Healthcare Services). TM was used in four remote locations; the FTF method was applied in two regional clinics. The treatment protocol was performed by a nurse and supervised by the regional physician in both treatment modes. A validated Wound-QoL questionnaire in Hebrew was used to assess patient outcomes. Results: A total of 83 patients were treated via TM and 94 patients were treated FTF. The mean QoL for patients treated via TM was 0.546±0.249 compared with 0.507±0.238 for the FTF group. A similarity relating to outcomes in both treatment methods was demonstrated by a difference of 0.039 (95% confidence interval –0.33–0.111) and p=0.291. The probability of the difference being within the limits of the interval in a replicated study was 83.4%. The equivalence/non-inferiority was established within the accepted Δ=0.12 range. Conclusion: The results indicated no reduced QoL for patients with LEUs treated with telemedicine versus with standard FTF care. Declaration of interest: The authors have no conflicts of interest.
Incidence and risk factors for pressure injuries in adults in specialised medical care: a prospective observational study
Authors: Stoltenberg Sanna , Kotila Jaana , Heikkilä Anniina , Kvist Tarja , Junttila Kristiina 
Published: November 2021

Introduction: Hospital-acquired pressure injuries are one of the most important indicators of quality patient care. It is important to identify high-risk patients to guide the implementation of appropriate prevention strategies. This can be done by using an assessment tool that covers the main risk factors for pressure injuries. Aim: The purpose of the study was to describe the incidence of pressure injuries and the associated risk factors among patients assessed with the Prevent Pressure Injury (PPI) risk assessment tool developed by the Helsinki University Hospital. Method: The study was conducted by selecting six wards from medical, surgical and neurological units. The target group were the patients being treated in the study units who gave their informed consent. The research data were retrieved from electronic patient records. Results: From the target group, 332 patients were eligible to participate in the study. The pressure injury risk was found to increase with longer hospital stays and older age. Surgical patients had an increased risk of pressure injuries compared to other specialty fields. A primary diagnosis of musculoskeletal or connective tissue disease, and secondary diagnoses of hypertension and cerebral haemorrhage, were linked with an increased pressure injury risk. A total of nine pressure injuries occurred in nine patients, with an incidence of 2.5% (stages II−IV). Conclusion: The observation and recording of pressure injuries in specialised medical care remain insufficient. Longer hospital stays, older age and surgery increase pressure injury risk. Also, patients' primary and secondary diagnoses may increase the pressure injury risk. Declaration of interest: The authors have no conflicts of interest to declare.
Giving travel advice in the uncertain age of COVID-19
Authors: Spinks Jacqueline , Balachandiran Kirishanthy , Birdseye James , Barker-Burnside Ceri , Cumiskey Kerry , Olufon Oluwakemi , Sanchez Adrian , Staines Robert , Wedgwood Kate , Beckett Gail 
Published: November 2021

As restrictions ease and more people holiday overseas, the importance of providing accurate travel health advice increases. Jacqueline Spinks and colleagues provide an overview of current guidance The COVID-19 pandemic has led to a dramatic drop in people travelling to other countries for pleasure; however, now that restrictions across the UK are easing, more people are seeking a break and a long-awaited holiday overseas. Practice nurses are uniquely placed to provide travel advice not just in relation to COVID-19 requirements and restrictions, but also to remind travellers of the importance of being prepared for all other communicable diseases and travel-related hazards. This article aims to provide a summary of the latest and up to date information in England (links to guidance covering the Devolved Administrations of Scotland, Wales and Northern Ireland are found in Box 1 ) and covers a summary of COVID-19, current guidance on travel during the pandemic, information about pre-planning for overseas travel, return from travel and information about being identified as a contact during travel, general travel advice; and ends with links to the most relevant guidance and information available.
Diagnosing COPD in general practice
Authors: Rodman Anne 
Published: November 2021

COPD prevalence is likely to be underestimated in the UK. Anne Rodman explores the current evidence base for diagnosing COPD Chronic obstructive pulmonary disease (COPD) is an umbrella term for several different pathological processes in the lungs of susceptible individuals. COPD should be considered in any patient who has symptoms and a history of exposure to risk factors for the disease. The cornerstone of COPD diagnosis is to identify risk factors for this preventable condition, recognise and investigate any symptoms that are not commonly found in COPD, and confirm that obstruction is present with correctly performed and interpreted spirometry. This article explores the current evidence base for diagnosing COPD, how to differentiate it from asthma and other conditions with similar symptoms, and the rationale for specialist referral.
Advanced practice education and development
Authors: Henderson Colette 
Published: November 2021

Colette Henderson looks at the importance of education and development for advanced practitioners UK government policy directives support the development of multidisciplinary advanced practice roles. Advanced practitioners must align their practice and subsequent continuing professional development (CPD) with four pillars of practice: clinical practice; facilitation of learning; leadership and evidence; and research and development. Lifelong learning is a mandatory requirement for healthcare practitioners. This article will focus on the importance of education and development for advanced practitioners and starts by providing some detail of the background development of advanced practice in the UK to justify the focus on ongoing achievement of capability across the four pillars.
Confinement Behavior
Authors: García-Castillo Fernando , Ramos-Soler Irene , García-del-Castillo José A. 
Published: November 2021

Some events are drivers for a change in the way we live life. When these events are not controllable, as has been the case with the coronavirus pandemic, everything is precipitated and the mechanisms of change are accelerated regardless of the type of culture, society, or economy in which they take place. Possibly it is the circumstances that directly affect the health of the population that are the most critical and are the ones that cause the greatest concern and change.
This is the first time in history that we have had the opportunity to study lockdown behavior at a global level, analyzing how it affects citizens’ way of life. The most widespread restrictions in most countries of the world have revolved around increasing physical distance, lockdowns (total, by districts, or by specific areas), curfews (variable depending on the severity of the situation of each place), mandatory isolation in the case of testing positive for the infection, the suppression of all kinds of activities (cultural, sports, leisure), and the promotion of remote working to avoid, as much as possible, being in contact with others.
The two main characteristics of mandatory isolation are, on the one hand, complete physical isolation from family and friends and, on the other, the absolute restriction of free movement. Both measures, also being combined with other factors, can generate significant changes in the levels of anxiety and stress of confined people. This is due to these people experiencing emotions of fear regarding illness and death, the possible loss of their jobs, the consequent economic problems, and the probability of increasing their level of being sedentary as a result of not being able to go outside to exercise.
In this study, we propose, from a theoretical point of view, the precedents and consequences of lockdown behavior regarding the dimensions that we consider fundamental in people's lives. We analyze how lockdown influences lifestyle, from eating habits to sleeping patterns, digital behavior, physical activity, and emotional state, reaching the theoretical conclusion that all of these aspects can be significantly altered.
A feasibility study to assess the design of a multicentre randomized controlled trial of the clinical and cost-effectiveness of a caregiving intervention for people following hip fracture surgery
Authors: Smith Toby , Clark Lucy , Khoury Reema , Man Mei-See , Hanson Sarah , Welsh Allie , Clark Allan , Hopewell Sally , Pfeiffer Klaus , Logan Pip , Crotty Maria , Costa Matthew , Lamb Sarah E. 
Published: November 2021

Aims This study aims to assess the feasibility of conducting a pragmatic, multicentre randomized controlled trial (RCT) to test the clinical and cost-effectiveness of an informal caregiver training programme to support the recovery of people following hip fracture surgery. Methods This will be a mixed-methods feasibility RCT, recruiting 60 patients following hip fracture surgery and their informal caregivers. Patients will be randomized to usual NHS care, versus usual NHS care plus a caregiver-patient dyad training programme (HIP HELPER). This programme will comprise of three, one-hour, one-to-one training sessions for the patient and caregiver, delivered by a nurse, physiotherapist, or occupational therapist. Training will be delivered in the hospital setting pre-patient discharge. It will include practical skills for rehabilitation such as: transfers and walking; recovery goal setting and expectations; pacing and stress management techniques; and introduction to the HIP HELPER Caregiver Workbook, which provides information on recovery, exercises, worksheets, and goal-setting plans to facilitate a ‘good’ recovery. After discharge, patients and caregivers will be supported in delivering rehabilitation through three telephone coaching sessions. Data, collected at baseline and four months post-randomization, will include: screening logs, intervention logs, fidelity checklists, quality assurance monitoring visit data, and clinical outcomes assessing quality of life, physical, emotional, adverse events, and resource use outcomes. The acceptability of the study intervention and RCT design will be explored through qualitative methods with 20 participants (patients and informal caregivers) and 12 health professionals. Discussion A multicentre recruitment approach will provide greater external validity across population characteristics in England. The mixed-methods approach will permit in-depth examination of the intervention and trial design parameters. The findings will inform whether and how a definitive trial may be undertaken to test the effectiveness of this caregiver intervention for patients after hip fracture surgery. Cite this article: Bone Jt Open 2021;2(11):909–920.
Luminous efficiency improvement of polymer light-emitting diodes with platinum nanolayer at the PEDOT:PSS–ITO interface
Authors: Chen Sy-Hann , Hsu Pei-Ju 
Published: November 2021

A platinum (Pt) nanolayer was successfully deposited on indium titanium oxide (ITO) as a buffer layer for polymer light-emitting diodes (PLEDs) using a rapid and low-cost sputtering system at room temperature. With a 5 s Pt-dispersed ITO as the anode window substrate of the PLED, a maximum current efficiency of 4.00 cd/A was realized, which is notably higher than that of a typical PLED (1.13 cd/A). It was determined that the average current efficiency and electroluminescence intensity of the proposed PLED were enhanced by 2.5 times and 290%, respectively, compared to a typical PLED.
Double perovskite microcrystals-based white light-emitting diodes without reabsorption of multiphase phosphors
Authors: Yang Gang , Zhu Yongsheng , Li Xueguo , Huang Jinshu , Xu Xiumei , Ji Xiaoxu , Wang Aihua , Cheng Jinbing , Pan Gencai 
Published: November 2021

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Dating violence and associated factors among male and female adolescents in Spain
Authors: Vives-Cases Carmen , Pérez-Martínez Vanesa , Davó-Blanes MCarmen , Sánchez-SanSegundo Miriam , Gil-González Diana , G. Abiétar Daniel , Sánchez-Martínez Francesca , Forcadell-Díez Lluís , Pérez Glòria , Sanz-Barbero Belén 
Published: November 2021

Background
Dating Violence (DV) is a public health problem that is on the rise. In this paper, we aim to analyse different factors associated with DV victimization among female and male adolescents in Spain, considering socioeconomic circumstances, sexual orientation and the presence of different attitudes and experiences related to violence.

Methods
Cross-sectional data from a convenience sample of 640 ever-partnered adolescents aged 13 to 17 at schools in the cities of Alicante (n = 359, 50.1% girls) and Terrassa (n = 281, 51.9%) in the context of an educational intervention to promote healthy relationships. We calculated the prevalence of different forms of DV (physical, sexual and control and fear) and carried out multivariate regression models by sex.

Results
5.5% of girls and 8.7% of boys declared having suffered lifetime physical and/or sexual violence, while 22% of girls and 20.5% of boys reported control and/or fear victimization. The likelihood of DV was higher among migrants and those with foreign-born parents (aPR girls = 2.1 CI95%: 1.1–3.9; aPR boys = 1.9: CI95%: 1.0–3.6); prior experiences of abuse (aPR girls = 1.6; CI95%: 1.0–2.6; aPR boys = 1.7; CI95%: 1.1–2.6); and those who showed higher levels of machismo (aPR girls = 1.0; CI95%: 1.0–1.1; aPR boys = 1.0; CI95%: 1.0–1.1). In girls, DV increased among those who reported lesbian/bisexual orientation and poor relationship with teachers.

Conclusions
DV is socially patterned and increases among LGB adolescents (especially in the case of girls), migrants, and those with foreign-born parents, and adolescents who reported prior experiences of violence in childhood. Future DV prevention programs should consider social inequalities in the likelihood of DV and by reinforcing adolescents’ abilities to recognize social support sources and reject machismo and violence.
High variability in transmission of SARS-CoV-2 within households and implications for control
Authors: Toth Damon J. A. , Beams Alexander B. , Keegan Lindsay T. , Zhang Yue , Greene Tom , Orleans Brian , Seegert Nathan , Looney Adam , Alder Stephen C. , Samore Matthew H. 
Published: November 2021

Background
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a high risk of transmission in close-contact indoor settings, which may include households. Prior studies have found a wide range of household secondary attack rates and may contain biases due to simplifying assumptions about transmission variability and test accuracy.

Methods
We compiled serological SARS-CoV-2 antibody test data and prior SARS-CoV-2 test reporting from members of 9,224 Utah households. We paired these data with a probabilistic model of household importation and transmission. We calculated a maximum likelihood estimate of the importation probability, mean and variability of household transmission probability, and sensitivity and specificity of test data. Given our household transmission estimates, we estimated the threshold of non-household transmission required for epidemic growth in the population.

Results
We estimated that individuals in our study households had a 0.41% (95% CI 0.32%– 0.51%) chance of acquiring SARS-CoV-2 infection outside their household. Our household secondary attack rate estimate was 36% (27%– 48%), substantially higher than the crude estimate of 16% unadjusted for imperfect serological test specificity and other factors. We found evidence for high variability in individual transmissibility, with higher probability of no transmissions or many transmissions compared to standard models. With household transmission at our estimates, the average number of non-household transmissions per case must be kept below 0.41 (0.33–0.52) to avoid continued growth of the pandemic in Utah.

Conclusions
Our findings suggest that crude estimates of household secondary attack rate based on serology data without accounting for false positive tests may underestimate the true average transmissibility, even when test specificity is high. Our finding of potential high variability (overdispersion) in transmissibility of infected individuals is consistent with characterizing SARS-CoV-2 transmission being largely driven by superspreading from a minority of infected individuals. Mitigation efforts targeting large households and other locations where many people congregate indoors might curb continued spread of the virus.
Japanese Merchants Diaspora in the 17th Century into Southeast Asia
Authors: Surya Riza Afita 
Published: November 2021

This study aimed to investigate the Japanese Diaspora in the 17th century into Southeast Asia. This article discussed critically the motives, process, and the effect of Japanese diaspora in the Southeast Asia. Reseacher utilized historical method with descriptive approach. The process being performed namely heuristics, critism, interpretation, and historiography. Japanese history regarding abroad migration is an interesting issue between scholars who studied migration, anthropology, and minority studies over the decades. Edo period in Japan is one of the most studied field for many scholars for Japanese studies, since it shaped the characteristic of Japanese culture until today. Trade of Japan is significant part of its economical development since the pre-modern era. In the 17th century, Japan established a solid trade network with Southeast Asia regions, namely Siam, Malacca, Cambodia, Vietnam and Manila. The emerge of maritime trade with Southeast Asia encouraged Japanese merchants to travel and create settlements in some regions. The Japanese diaspora was encouraged with vermillion seal trade which allowed them to do journey overseas and settled in some places, which eventually increased the number of Japanese merchants in the Southeast Asia. However, after the Sakoku policy there was restriction of trade relation ehich prohibited overseas maritime trade, except for China and Dutch. Sakoku policy caused Japanese merchants who stayed overseas could not return for many years, then they settled themselves as Japanese communities known as Nihon Machi in some places within Southeast Asia. History of early modern Japan between the 16th and 19th century provides a broader narratives of global history as it was surrounded by intense global interaction.
Dr. INFLUENCE OF JOB BURNOUT ON INTENTION TO QUIT AMONG HEALTH SERVICE EMPLOYEES IN SOUTHWESTERN NIGERIA
Authors: Adewa Kehinde , Tosin-Amos Aderonke , Ilori Taiwo Adeola 
Published: November 2021

This paper examined the influence of job burnout on intention to quit among health service employees in Southwestern Nigeria because there has been limited attention on the influence of job burnout on intention to quit. The study population is 18,295. A sample of 380 respondents were obtained using Yamane formula. Questionnaire was administered to Nurses, Administrators, Doctors, Technologists and Pharmacists with full employment status. Data was analysed with the use of Multiple regression aided by Path Analysis. The study revealed that job burnout significantly affect intention to quit. Emotional Exhaustion (t = 3.126, p < 0.05); Depersonalization (t = 0.930, p < 0.05); Personal Accomplishment (t = 1.773, p < 0.05). The study concluded that job burnout affects intention to quit among health service employees in Southwestern Nigeria.
Keywords: Job Burnout, Employment Alternative, Professional Commitment, and Social Support.