bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH LAYANAN INFORMASI MELALUI DARING TERHADAP PENINGKATAN MINAT STUDI LANJUT KE PERGURUAN TINGGI PADA SISWA SMA N 3 SUKOHARJO
Authors: Mahmuddah Dewi Edmawati  , Aldila Fitri Radite Nur Maynawati  , Candra Giri Murti  
Published: October 2021

Abstrak: Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh layanan informasi secara daring dapat meningkatkan minat siswa SMA N 3 Sukoharjo untuk melanjutkan studinya ke Perguruan Tinggi. Metode dalam penelitian ini peneliti menggunakan metode kuantitatif ekperimen. Penelititan kuantitatif tidak mempermasalahkan hubungan antara peneliti dengan subyek penelitian karena hasil penelitian lebih banyak tergantung dengan instrumen yang digunakan dan terukur variabel yang digunakan, dari pada intim dan keterlibatan emosi antara peneliti dengan subyek yang diteliti. Hasil penelitian adalah ada pengaruh yang signifikan terhadap pemberian layanan informasi secara daring kepada siswa kelas XI MIPA 3 SMA Negeri 3 Sukoharjo tahun pelajaran 2020/2021 untuk melanjutkan pendidikanya ke Perguruan Tinggi. Hasil penelitian dengan menggunakan perhitungan uji Paired Sample T-Test pada Pre Test dan Post Test menunjukkan nilai Signifikansi (2-tailed) 0,000 < 0,05 , artinya menunjukkan adanya perbedaan yang signifikan antara variabel awal dengan variabel akhir. Ini menunjukkan terdapat pengaruh yang bermakna terhadap perlakuan yang diberikan pada masing-masing variabel. Sehingga dapat disimpukan bahwa: “Terdapat pengaruh pemberian layanan informasi secara daring mengenai studi lanjut terhadap minat siswa kelas XI MIPA 3 SMA Negeri 3 Sukoharjo tahun pelajaran 2020/2021 untuk melanjutkan pendidikanya ke Perguruan Tinggi.
Kata Kunci : layanan informasi, daring, minat studi lanjut
IMPLEMENTASI PEMBELAJARAN PENDIDIKAN AGAMA ISLAM BERBASIS INTERNET DI SMA NEGERI 1 PAMEKASAN
Authors: Zulkarnayn Diki , Thoha Mohammad 
Published: October 2021

The implementation of Internet-Based Islamic Education Learning at SMAN 1 Pamekasan feels increasingly needed to be used as an alternative in fostering students' motivation and enthusiasm for learning, especially PAI learning. This study aims to examine teachers and students in innovating internet-based PAI learning, the obstacles experienced by teachers and students in implementing internet-based PAI learning, and also the implications of internet-based PAI learning at SMAN 1 Pamekasan. The focus of research in this study are: (1) How is the implementation of Internet-based PAI learning media at SMAN 1 Pamekasan? (2) What are the barriers to Internet-based PAI learning at SMAN 1 Pamekasan? (3) What is the solution to the obstacles to Internet-based PAI learning at SMAN 1 Pamekasan?
This study uses a qualitative approach which intends to understand the phenomenon of what is experienced by the research subject. Data collection techniques carried out by researchers are interviews, non-participant observations, and documentation of a number of related sources. Data analysis during the research and after the research took place using data reduction, data presentation, and data verification for field studies.
The results of the study indicate that: First, the implementation of internet-based PAI learning at SMAN 1 Pamekasan is quite adequate and is highly responded to by the principal, teachers, especially students. Although not 100% but with internet-based PAI learning, it is easy for teachers and students to carry out learning in class, which was originally boring to be fun and more efficient. Students who miss lessons can directly access learning by using the internet. Second, obstacles. Internet-based PAI learning at SMAN 1 Pamekasan is by providing training to PAI teachers regarding the implementation of internet-based learning, so that teachers who are less able to operate the internet can be helped by other PAI teachers. Third, student learning solutions and the use of internet-based PAI learning implementation at SMAN 1 Pamekasan, can be seen from the activeness of students in class and the results of student evaluations. To the principal of SMAN 1 Pamekasan for always providing support to teachers, especially PAI teachers related to internet media for the advancement of education at SMAN 1 Pamekasan. This support is by involving teachers in workshops or training on the implementation of internet-based PAI learning.
Kata Kunci: Pembelajaran PAI, Berbasis Internet
Dynamical Chaos and Lateral Transport of a Passive Scalar in the Annular Reverse Jet Flow
Authors:   Institute of Applied Physics, RAS, Reutov V. P. ,   Institute of Applied Physics, RAS, Rybushkina G. V. 
Published: October 2021

The transition to dynamical chaos and the related lateral (cross-flow) transport of a passive scalar in the reverse annular jet flow generating two chains of wave-vortex structures are studied. The quasi-geostrophic equations for the barotropic (quasi-two-dimensional) flow written in polar coordinates with allowance for the beta-effect and external friction are solved numerically using a pseudospectral method. The critical parameters of the equilibrium flow with a complex “two-hump” azimuth velocity profile facilitating a faster transition to the complex dynamics are determined. Two regular multiharmonic regimes of wave generation are revealed with increasing flow supercriticality before the onset of Eulerian chaos. The occurrence of the complex flow dynamics is confirmed by a direct calculation of the largest Lyapunov exponent. The evolution of streamline images is analyzed by making video, thereby chains with single and composite structures are distinguished. The wavenumber-frequency spectra confirming the possibility of chaotic transport of the passive scalar are drawn for the basic regimes of wave generation. The power law exponents for the azimuth particle displacement and their variance, which proved the occurrence of the anomalous azimuth transport of the passive scalar, are determined. Lagrangian chaos is studied by computing the finite-time Lyapunov exponent and its distribution function. The internal chain (with respect to the annulus center) is found to be totally subject to Lagrangian chaos, while only the external chain boundary is chaotic. It is revealed that the cross-flow transport occurs only in the regime of Eulerian dynamical chaos, since there exists a barrier to it in the multiharmonic regimes. The images of fluid particles confirming the presence of lateral transport are obtained and their quantitative characteristics are determined.
DNA Damage Induced Cellular Senescence and It’s PTEN Armed Exosomes - The Warriors Against Prostate Carcinoma Cells
Authors: Karmakar Parimal , Chowdhury Sougata Ghosh , Ray Rachayeeta , Bhattacharya Debalina 
Published: October 2021

Abstract
Exosomes are one type of small extracellular vesicles having a size range of 30–150 nm and secreted by the endosomal compartment of most eukaryotic cells. It has been found that exosomes can serve as a communicating vehicle to transfer information among cells and thus can be associated with numerous physiological and pathological functions. In this study, we have isolated exosomes from two different human cancer cell lines. Isolated exosomes were characterized by scanning electron microscopy, DLS and by western blotting. It was observed that exosomes isolated from mock treated human lung epithelial carcinoma (A549) cells or Hela cells exerted growth arrest to the human prostate carcinoma (PC3) cells, but no growth arrest was observed in case of normal human lung fibroblast cell line (WI38). Additionally, exosomes isolated from PC3 cells have no effect on PC3 cells. This is also true for exosomes isolated from H2O2 induced senescent human lung cancer cells (A549). Analysis of exosome content by western blotting reveals the presence of PTEN in the exosome of lung cancer cells. Functional analysis of PTEN pathways in PC3 cells indicates the inactivation of Akt in exosome treated cells. Therefore, from our study we have concluded that exosomes secreted from A549 cells which contain functional PTEN, may be used for delivery of PTEN to cancer cells without functional PTEN.
Incidence and Risk Factors for Postoperative Venous Thromboembolism in Patients with Endometrial Cancer: Systematic Review and Meta-analysis
Authors: Zheng Xing , Hou XiaoYing , Wang Qing , Zhang Ying 
Published: October 2021

Abstract
Background: Venous Thromboembolism (VTE) is a leading reason of morbidity and mortality in endometrial cancer patients. There is no meta-analysis available on this topic so far. In order to identify relevant risk factors contributing to VTE and form strategies to prevent VTE, we conducted the present study to quantitatively analyze the data from studies with the incidence and risk factors among cases with endometrial cancer.Methods: PubMed, Embase and CNKI were searched for papers containing the key words “thromboembolism” “endometrial cancer” and their variants. Studies selection, data extraction, quality assessment of eligible studies were performed independently by two reviewers. Meta-analyses were conducted to determine postoperative VTE incidence rate and risk factors in endometrial cancer. Sensitivity analysis was used to verify the robustness of the results in the present study.Results: 8 studies were included in this meta-analysis totally. The pooled incidence rate for postoperative VTE was 7% (95% CI, 0.04 –0.09).The presence of age>60 (OR, 2.26), tumor size in uterine cavity(＞60mm) (OR, 5.68), tumor extension (CT/MRI) (OR, 5.59), FIGO stage (OR, 2.92), massive ascites (OR, 3.78), clear cell cancer (OR, 4.78) and CA125(＞35U/ml) (OR, 5.05) increase the likelihood of having postoperative VTE remarkably. Conclusions: The present study revealed that VTE is a prevalent complication in postoperative patients with endometrial cancer. The patients with the following risk factor including female elderly, large size of tumor, advanced endometrial cancer，massive ascites , elevated CA125 and special histology should be altered VTE occurrence.
Bioinformatics analysis of differentially expressed genes and their potentially interacting miRNAs in oral lichen planus
Authors: Zhang Churen , Sun Ruoran 
Published: October 2021

Abstract
Background. Among the diseases of oral mucosa, oral lichen planus (OLP) is characterized by chronic autoimmune/autoinflammation. However, the etiology and pathogenesis of OLP were still limited. The aim of this research was to identify the differentially expressed genes and their potentially interacted miRNAs in OLP to provide a possible explanation of the pathogenesis of OLP and therapeutic biomarkers.Methods. The OLP microarray dataset (GSE52130) was download from the Gene Expression Omnibus (GEO) database. R software was used to identify differentially expressed genes between the OLP samples and normal oral mucosa. Functional enrichment analysis of DEGs, including Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, were conducted. Protein–protein interaction (PPI) network analysis was performed in the STRING database. CytoHubba in the Cytoscape software was applied to determining the top 10 hub genes, whose relative miRNA was identified through RNA Interactome Database.Results. Overall, 627 DEGs was identified in OLP samples, including 351 highly expressed genes and 276 lowly expressed genes. GO analysis indicated that the epidermal differentiation was mostly enriched. For the KEGG pathway, the DEGs in OLP samples were mostly involved in Staphylococcus aureus infection, Estrogen signaling pathway, Serotonergic synapse and Histidine metabolism. Top 10 hub genes including LOR, LCE3D, LCE3E, LCE1B, LCE2B, SPRR2E, SPRR2G, LCE2A, RPTN and CDSN were identified from the PPI network. The miRNA (hsa-miR-98-5p) was regarded as the mostly possible miRNA involved in OLP.
LncRNA-ENST00000543604 Exerts a Tumor-Promoting Effect via miRNA 564/AEG1 or ZNF326/EMT and Predicts The Prognosis of and Chemotherapeutic Effect in Colorectal Cancer
Authors: Wang Weimin , Zhou Zhen , Dai Xiaojun , Wang Haibo , Jin Jun , Min Ke , Wang Yunfan , Lv Mengying , Liu Yanqing , Zhou Yan 
Published: October 2021

Abstract
Background:Colorectal cancer is a common malignant tumor. Recent studies have found that lncRNAs play an important role in the occurrence and development of colorectal cancer.Methods:Based on high-throughput sequencing results of fresh CRC tissues and adjacent tissues, we identified lncRNA-ENST00000543604 (lncRNA 604) as the research object by qRT-PCR in CRC tissues and cells. The FISH method was used to detect the location of lncRNA 604 in cells, and its expression was detected on a tissue chip. We explored the mechanism of lncRNA 604 action by using luciferin reporter, qRT-PCR and Western blot assays. Kaplan-Meier survival analysis and a Cox regression model were used to analyze the correlation of lncRNA 604 and its regulatory molecules with the prognosis of and chemotherapy efficacy in CRC patients.Results:In this study, we found that the expression levels of lncRNA 604 were increased in CRC. LncRNA 604 could promote CRC cell proliferation and metastasis through the miRNA 564/AEG-1 or ZNF326/EMT signaling axis in vivo and in vitro. LncRNA 604 could predict the prognosis of CRC and was an independent negative factor. LncRNA 604 exerted a synergistic effect with miRNA 564 or ZNF326 on the prognosis of CRC. LncRNA 604 could improve chemoresistance by increasing the expression of AEG-1, NF-κB, and ERCC1.Conclusions:Our study demonstrated that lncRNA 604 could promote the progression of CRC via the lncRNA 604/miRNA 564/AEG-1/EMT or lncRNA 604/ZNF326/EMT signaling axis. LncRNA 604 is an independent and effective molecule for predicting the prognosis of CRC. LncRNA 604 could improve chemoresistance by increasing drug resistance protein expression.
Blue-Light Transmittance In Sunglasses Over Long-Term Irradiation Within A Solar Simulator
Authors: Masili Mauro , Duarte Fernanda Oliveira , Ventura Liliane 
Published: October 2021

Abstract
Blue-light transmittance in sunglasses plays an important role for the consumer regarding eye health. Current standards do not have specific requirements for blue-light protection, as in the past. However, the literature has warned about the potential harms of blue light for the eye. The limits imposed in the past state that the average transmission in the 380 nm to 500 nm region should not exceed 1.2X the transmittance in the visible range (380 nm – 780 nm). This work investigates, besides the transmittance of blue light in sunglasses, whether those limits imposed aiming to eye health are respected. Additionally, this study examines the blue-light transmittances pre- and post-artificially aging the material in a solar simulator. Twelve samples of sunglasses were tested for compliance with a former standard and submitted to the aging process up to 2500 h within the solar simulator. The results showed relevant changes in the lenses over time, that is, they considerably lost their blue-light attenuation capabilities. The results suggest that the aging test should be carried out on sunglasses not only for ultraviolet radiation, as required by most standards, but also for blue light. Furthermore, the standards should comprise some constraints concerning the blue-light attenuation.
Nanocomposite Obtained in the Plasma of a Pulsed High Voltage Discharge Using Nickel Electrodes and PTFE
Authors: Kuryavyi Valerii Georgievich , Zverev Grigorii Aleksandrovich , Tkachenko Ivan Anatol'evich , Slobodyuk Arseny Borisovich , Gerasimenko Andrei Vladimirovich , Ustinov Aleksandr Yur'evich , Bouznik Vjacheslav Mihajlovich 
Published: October 2021

In the plasma of pulsed high-voltage discharge, initiated between nickel electrodes in air, when the fluoroplastic is placed in the discharge gap, powder nanocomposite material has been synthesized. The nanocomposite contains NiF2 nanoparticles less than 5 nm in size, dispersed in a matrix consisting of carbon and fluorocarbon substances. The carbonaceous substance contains nanoscale disordered graphite-like regions. The fluorocarbon component of the composite contains fragments of PTFE molecules and fluorocarbon molecular fragments that differ in structure from PTFE molecule’s structure. After annealing the composite in air at 773 K, the initial nanocomposite is transformed into a nanocomposite containing nanosized PTFE and nanoparticles of NiF2 less than 5 nm in size, scattered in a matrix composed of nanographite and low-layer nanosized graphene, after aneling at 1173 K into a material containing NiO nanoparticles less than 10 nm in size. After annealing of the initial nanocomposite in argon atmosphere at 1073 K, the obtained nanocomposite contains Ni nanoparticles with sizes less than 5 nm and carbon and fluorocarbon components. The magnetic susceptibility of the unannealed nanocomposite is investigated. A transition to the antiferromagnetic phase at 73 K was detected. At T = 4K, exchange bias interaction of the AFM / FM type takes place in the composite. There is divergence of the FC and ZFC curves, which can be explained by the presence of a superparamagnetic phase or a spin glass phase in the sample. The field dependences of the magnetic susceptibility measured at T = 300 K show sharp changes that occur at certain values of the magnetic field. Elucidation of the nature of these changes requires additional research.
COUNSELING. UNA PERSPECTIVA SISTÉMICA Y ECOLÓGICA
Authors: López Bátiz Mónica 
Published: October 2021

La perspectiva sistémica-ecológica del counseling, es el resultado de un análisis, discusión e integración entre los fundamentos filosóficos y antropológicos que aporta la educación familiar y los fundamentos epistemológicos que sustentan a la psicoterapia breve sistémica.
La educación familiar es un proceso de perfeccionamiento humano, que influye en todos los ámbitos de la vida del ser humano; su objeto de estudio es el perfeccionamiento de la persona desde y en la familia para alcanzar su plenitud.
La psicoterapia sistémica e una rama de la psicología aplicada que toma como fundamento a la Teoría General de los Sistemas (TGS) y a la cibernética para explicar la mente y la conducta humanas.
El objetivo de esta nota es aportar una perspectiva para integrar un estilo de counseling sistémico-ecológico. Se puntualizan los alcances, fines, principios, contenidos, recursos y las estrategias; así como algunas recomendaciones para
Borrelia spp. ASOCIADAS CON ANFIBIOS Y REPTILES
Authors: Colunga-Salas Pablo Francisco , Betancur-Garcés Y. Camilo , Ochoa-Ochoa Leticia M. , Guzmán-Cornejo Carmen , Sánchez-Montes Sokani , Becker Ingeborg 
Published: October 2021

El género Borrelia es un grupo de bacterias helicoidales el cual está divide filogenéticamente en tres clados principales, el que comprende a las borrelias asociadas con reptiles, el que incluye al agente causal de la Fiebre Recurrente y el grupo de Borrelia burgdorferi s.l. Dada la importancia de las borrelias como agentes patógenos, el objetivo del presente trabajo fue recopilar la información existente hasta el 2017 acerca de las borrelias detectadas en los reptiles y sus garrapatas asociadas. Para ello se realizó una búsqueda bibliográfica exhaustiva. Se encontró un total de 26 artículos publicados. Un total de 20 especies de reptiles y anfibios han sido registradas como potenciales hospederos de Borrelia, destaca el orden Squamata con 17 especies, seguido por el orden Testudines con tres especies positivas para alguna especie de Borrelia. Asociados con los reptiles, se encontraron 11 especies de garrapatas duras (7 Amblyomma, 3 Ixodes, 1 de Dermacentor y 1 Hyalomma) positivas con al menos una especie de Borrelia. Los principales estudios en los cuales se han obtenido evidencias acerca de la presencia de Borrelia en reptiles se concentran en la zona centro de Europa, Portugal, Japón, Túnez, así como en el Este y Oeste de E.U.A. Con estos resultados, se mantiene la posibilidad de que este grupo de vertebrados como hospederos competentes que participan en el mantenimiento del ciclo selvático para algunas especies de Borrelia. Finalmente, consideramos necesario formar grupos interdisciplinarios para aumentar los estudios sobre las relaciones entre reptiles, sus ectoparásitos asociados y patógenos, con el fin de generar conocimiento que pueda ser de ayuda para la vigilancia epidemiológica en fauna silvestre y su relación con casos humanos.
Precatio Terrae y la Precatio omnium herbarum a un texto inacabado: las precationes herbarum de un recetario médico tardoantiguo
Authors: Ferraces Rodríguez Arsenio 
Published: October 2021

The Curae herbarum is a late antique medical recipe book made up of 64 chapters; it is mostly based on a Latin translation of the De materia medica by Dioscorides. Chapters 1–32 always end with a precatio to the plant so that it ‘comes with all its healing powers’. The article argues for an erudite origin for the precationes of the Curae herbarum, which borrow epithets, phraseology, and verbs of entreaty from the Precatio Terrae and the Precatio omnium herbarum. Moreover, the study of internal references in the precationes demonstrates that they were written with the intention of being placed before the medical recipes, but, for unknown reasons, were instead copied at the end of the chapters without ever occupying the place they were intended for.
Sofocle: Magia, Medicina, Religione
Authors: Zamperini Enrica 
Published: October 2021

In Sophocles’ tragedies the interweaving of medicine, religion and magic produces a lot of meanings and concepts that show the complexity of the Greek thought of the Fifth century. In his tragedies, Sophocles shows his interest both in the magical and religious medicine and in the new Hippocratic medical science. The aim of this paper is to analyze the conceptual and lexical intertwining that reflects this interest, focusing on the character of Oedipus. In fact, Oedipus is the hero who best embodies this duplicity. At the beginning of the drama he assumes a rational investigation method through which he tries to discover Laius’ murderer and then to heal Thebes from the plague that afflicts it. However, his responsibility emerges during the tragedy; Oedipus’ fault has divine origin and makes him the first cause of the evil of the city. In the Oedipus at Colonus, Oedipus’ body is released from the contamination that had made him the origin of the plague and the hero’s body turns into a sort of magic amulet to protect the polis that will guard it when he will be dead.
Gemas Uterinas y la Terapéutica de las Piedras en la Obra de Oribasio de Pérgamo
Authors: López Pérez Mercedes 
Published: October 2021

Uterine gems belong to a group of amulets, usually engraved on red minerals, such as jasper and carnelian; the most used is the hematite or “blood stone”. The iconography of the uterus in these gems refers to the mobility of the uterus, an idea already present in Plato's Timaeus (Pl., Ti. 91c.), and in the Greco-Roman medical texts, the wandering uterus theory. In this work we will complete the analysis of uterine gems with the use of stones as a therapeutic in the work of Oribasio de Pérgamo.