bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐Performance Flexible Micro‐Supercapacitors Printed on Textiles for Powering Wearable Electronics
Authors: Guo Hua , Jiang Zhen , Ren Dayong , Li Shengxia , Wang Jialin , Cai Xiaobing , Zhang Dongxing , Guo Qiuquan , Xiao Junfeng , Yang Jun 
Published: February 2021

AbstractFabrication of flexible micro‐supercapacitors (MSCs) on textiles as miniaturized power supplies for wearable electronics is still a great challenge. In this work, we proposed a facile protocol to fabricate MSCs directly on textiles by combining inkjet printing and extrusion printing. Benefiting from its multi‐step printing strategy, the textile‐based MSCs still maintain their unique porous electrode structure as well as rapid electron transferability. Compared with only extrusion printing, the MSCs with a multi‐step printing strategy exhibit a remarkably enhanced electrochemical performance (8.8 mF cm−2 @0.5 mA cm−2, 1.0 mF cm−2 @5 mF cm−2), an elongated cycle life (6000 times), and superior mechanical flexibility (2000 times @90°). Moreover, benefiting from the digital printing capability, flexible MSCs in serials can be directly prepared and conveniently integrated with conductive textiles to support wearable electronics systems. This simple printing method would show extensive potential in the fabrication of energy‐based devices and wearable functional electronics.
Design, Synthesis, and Evaluation of Fungicidal Activity of Novel Pyrazole‐Containing Strobilurin Derivatives†
Authors: Hao Zesheng , Wang Weibo , Yu Bin , Qi Xin , Lv You , Liu Xiaoyu , Chen Haoyin , Kalinina Tatiana A. , Glukhareva Tatiana V. , Fan Zhijin 
Published: February 2021

Main observation and conclusionIn searching for novel fungicidal leads, a series of pyrazole‐containing strobilurins were rationally designed, synthesized and characterized. Bioassay indicated that compound I‐7 displayed excellent fungicidal activity against a broad spectrum of plant pathogens such as Gibberella zeae, Rhizoctonia cerealis, Sclerotinia sclerotiorum, Phytophthora infestans, Physalospora piricola and Pellicularia sasakii with EC50 of 0.16, 0.02, 0.72, 0.07, 0.77 and 0.65 μg/mL, respectively, which were 3—10 times more potent than the positive control azoxystrobin against the corresponding pathogens. Moreover, like azoxystrobin and kresoxim methyl, I‐7, displayed excellent protective activity against P. sorghi. Molecular docking validated that I‐7 and azoxystrobin would share a similar binding mode with cytochrome bc1 complex. This study demonstrates that I‐7 is a promising fungicidal candidate for further development.
Organic Multiple Redox Semi‐Solid‐Liquid Suspension for Li‐Based Hybrid Flow Battery
Authors: Zhang Xuefeng , Zhang Peiyao , Chen Hongning 
Published: February 2021

AbstractLi‐based hybrid flow batteries are very promising in the energy storage market for their high cell voltage and scale‐up flexibility. However, the low volumetric capacity of catholyte has limited their practical application. A novel concept of organic multiple redox semi‐solid‐liquid (MRSSL) suspension was proposed and demonstrated by taking advantage of active materials in both liquid and solid phases in the suspension. In this study, high solubility of 2,2,6,6‐tetramethylpiperidine‐1‐oxyl (TEMPO) in the liquid phase and high reversibility of 10‐methylphenothiazine (MPT) composite in the solid phase were employed to develop a high‐performance and low‐cost organic MRSSL Li‐based hybrid flow battery. It achieved a small voltage gap (<0.1 V) between liquid and solid phase, high cell voltage (≈3.4 V) and high energy density (260 Wh L−1). Due to the synergistic interactions between the liquid‐phase TEMPO and the solid‐phase MPT, the viscosity of the MRSSL suspension was significantly reduced. An intermittent‐flow‐mode test of TEMPO‐MPT MRSSL suspension was conducted, which proved that the suspension had an applicable cycling performance with high volumetric capacity (50 Ah L−1). The organic MRSSL suspension concept offers a new approach to increase the volumetric capacity and energy density of Li‐based hybrid flow batteries by combining various low‐cost solid and liquid organic active materials.
Flow cytometric analysis of pollen and spores: An overview of applications and methodology
Authors: Kron Paul , Loureiro João , Castro Sílvia , Čertner Martin 
Published: February 2021

AbstractPollen grains are the male gametophytes in a seed‐plant life cycle. Their small, particulate nature and crucial role in plant reproduction have made them an attractive object of study using flow cytometry (FCM), with a wide range of applications existing in the literature. While methodological considerations for many of these overlap with those for other tissue types (e.g., general considerations for the measurement of nuclear DNA content), the relative complexity of pollen compared to single cells presents some unique challenges. We consider these here in the context of both the identification and isolation of pollen and its subunits, and the types of research applications. While the discussion here mostly concerns pollen, the general principles described here can be extended to apply to spores in ferns, lycophytes, and bryophytes. In addition to recommendations provided in more general studies, some recurring and notable issues related specifically to pollen and spores are highlighted.
Socio‐ecological lessons from the multiple landfalls of Hurricane Georges
Authors: Van Bloem Skip J. , Martin Patrick H. 
Published: February 2021

AbstractOver the course of 16 d in the fall of 1998, Hurricane Georges made landfall on five Caribbean Island nations, two U.S. states, and two territories. Along its path, it impacted nearly every type of built environment and terrestrial and marine ecosystem found in the Caribbean and the southeastern United States. We reviewed ecological and sociological research related to Georges in order to demonstrate the potential power of regional synoptic networks despite notable gaps that existed at the time. Most studies examined various effects and responses within four years of the storm, though a few reported longer‐term results. Reduction in forest stem density was the most reported ecological effect and ranged from 7% to 51% among sites in different forest types. Forests previously impacted by Hurricane Hugo in 1989 showed lower mortality from Georges than forests with longer hurricane‐free intervals. Rivers in the storm's path exported heavy loads of sediment to marine systems. For example, 5–10 million tons of sediment was transported to marine systems from Puerto Rico, and suspended sediments increased tenfold in coastal Louisiana. Economic costs directly related to Hurricane Georges ranged from 5% to 200% of annual GDP in the year after the storm. Sociological research indicated that children and college students exposed to Hurricane Georges experienced elevated effects on mental health such as anxiety and depression for up to 2.5 yr. Established research areas and longitudinal studies were valuable in understanding hurricane effects in the context of long‐term trends but fragmented research capacity reduced both local and regional synthetic efforts. Georges provides a template of how future integrated research programs could provide a deeper understanding of how nature, urbanization, human culture, and societal norms interact, respond, and recover from a major hurricane. However, future studies should avoid using the Saffir‐Simpson scale as a shorthand indicator or predictor of storm effects because topographic, historical, ecological, political, infrastructural, and societal factors interact to alter storm effects. The breadth of topics addressed in the research produced after Georges shows the potential for transformative, regionally synthetic research that spans whole watersheds and nearshore areas while integrating ecological and social sciences.
Malignancy rates and initial management of Thy3 thyroid nodules in a district general hospital: The ‘Reading’ experience
Authors: Nair Dilip , Kandiah Shivanthi , Rourke Thomas , Corbridge Rogan , Nagala Sidhartha 
Published: February 2021

AbstractBackgroundUltrasound‐guided fine‐needle aspiration cytology is the gold standard for investigating thyroid nodules. Stratifying the Thy3 thyroid nodule risk of malignancy is essential for clinical decision‐making. According to the Royal College of Pathologists Guidance (2016), the rate of malignancy for Thy3a is 5–15% and for Thy3f 15–30%. Our aim was to investigate the malignancy rate and the initial management of Thy3 nodules in our institution.MethodsA retrospective review was undertaken of 115 patients with Thy3 cytology results from thyroid fine‐needle aspirations performed between January 2015 and June 2020 at a single centre. A total of 90 out of 115 patients underwent surgery.ResultsOf the 90 patients, we had a 40% malignant rate (36/90). Specifically, 14 of 34 (41.1%) Thy3a and 22 of 56 (39.2%) Thy3f nodules were malignant. Of the malignant lesions, 52.7% (19/36) were follicular thyroid carcinoma. 58.8% (10/17) of male patients and 35.6% (26/73) of female patients had a malignant histology. Eighteen patients eventually needed a completion thyroidectomy.ConclusionCompared with national data, we showed a higher risk of malignancy in Thy3 nodules in our centre. Our study should encourage other centres to audit their own data. We propose setting up a national Thy3 registry as a basis to promote research in improving preoperative diagnosis of indeterminate thyroid nodules.
Implementation of weighted essentially non‐oscillatory scheme for unsteady and steady compressible flow in pressure‐based algorithm
Authors: Balaj Mojtaba , Djavareshkian Mohammad Hassan 
Published: February 2021

AbstractA pressure‐based semi‐implicit procedure has been developed for the computation of compressible flows on a system with collocated finite volume formulations. The method includes the implementation of a high‐order accurate weighted essentially non‐oscillatory scheme within the pressure‐based algorithm which employs an approximate Riemann solver for the computation of the cell face inviscid fluxes. The developed scheme is applied to the computation of unsteady compressible flow through a shock tube which experiences various Mach numbers, and the computations are compared with an analytical solution. The computations indicate that the developed procedure leads to sharp discontinuity representation without creation of spurious oscillations. Then, the developed numerical method is utilized to investigate unsteady two‐dimensional flow for a lax configuration and the results are compared with the results of the similar scheme in the density‐based algorithm. At the end, the investigation of steady compressible flows in bump and wedge channel is considered. The simulations show a considerable improvement over the existing pressure‐based method. The investigations show that the developed method is suitable for studying compressible steady and unsteady flows.
Vapor–liquid behavior of phenol and cumene in ternary and quaternary mixtures
Authors: Sprakel Lisette MJ , Bargeman G , Sanchez Lara G , Schuur B 
Published: February 2021

AbstractBACKGROUNDAlthough phenol is a key intermediate in the plastics and polycarbonate industry, it is also a toxic component that requires removal from dilute aqueous streams, potentially by liquid–liquid extraction (LLX). For LLX, cumene is suggested as a solvent as it is already present in processes in the polycarbonate industry. For the recovery of cumene from phenol by distillation, knowledge on vapor–liquid equilibrium (VLE) behavior is important, in combination with how this is affected by other components possibly present as an impurity or explicitly added as a solvent. This was investigated in this work.RESULTSThe binary cumene–phenol system shows a tangent pinch in the binary VLE diagram. Addition of a range of impurities and solvents showed that hydrogen bond accepting compounds strongly improve the relative volatility of the mixture, whereas dodecane, not capable of forming hydrogen bonds, has a negative effect on the relative volatility.CONCLUSIONAddition of polar components with hydrogen bonding abilities, i.e. ketones or ethers, affected the relative volatility of cumene over phenol the most positively. Combining two types of components results in similar effects, and clear synergistic effects could not be shown based on current VLE measurements. Addition of an apolar component in combination with polar components with hydrogen abilities had only a minor effect on the relative volatility. © 2021 The Authors. Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).
The Complex Genetic Landscape of Hereditary Ataxias in Turkey and Implications in Clinical Practice
Authors: Vural Atay , Şimşir Gülşah , Tekgül Şeyma , Koçoğlu Cemile , Akçimen Fulya , Kartal Ece , Şen Nesli E. , Lahut Suna , Ömür Özgür , Saner Nazan , Gül Tuğçe , Bayraktar Elif , Palvadeau Robin , Tunca Ceren , Pirkevi Çetinkaya Caroline , Gündoğdu Eken Aslı , Şahbaz Irmak , Kovancılar Koç Müge , Öztop Çakmak Özgür , Hanağası Haşmet , Bilgiç Başar , Eraksoy Mefkure , Gündüz Ayşegül , Apaydın Hülya , Kızıltan Güneş , Özekmekçi Sibel , Siva Aksel , Altıntaş Ayşe , Kaya Güleç Zeynep E. , Parman Yeşim , Oflazer Piraye , Deymeer Feza , Durmuş Hacer , Şahin Erdi , Çakar Arman , Tüfekçioğlu Zeynep , Tektürk Pınar , Çorbalı M. Osman , Tireli Hülya , Akdal Gülden , Yiş Uluç , Hız Semra , Şengün İhsan , Bora Elçin , Serdaroğlu Gül , Erer Özbek Sevda , Ağan Kadriye , İnce Günal Dilek , Us Önder , Kurt Semiha G. , Aksoy Dürdane , Bora Tokçaer Ayşe , Elmas Muhsin , Gültekin Murat , Kumandaş Sefer , Acer Hamit , Kaya Özçora Gül D. , Yayla Vildan , Soysal Aysun , Genç Gençer , Güllüoğlu Halil , Kotan Dilcan , Özözen Ayas Zeynep , Şahin Hüseyin A. , Tan Ersin , Topçu Meral , Topçuoğlu Esen Saka , Akbostancı Cenk , Koç Filiz , Ertan Sibel , Elibol Bülent , Başak A. Nazlı 
Published: February 2021

AbstractBackgroundThe genetic and epidemiological features of hereditary ataxias have been reported in several populations; however, Turkey is still unexplored. Due to high consanguinity, recessive ataxias are more common in Turkey than in Western European populations.ObjectiveTo identify the prevalence and genetic structure of hereditary ataxias in the Turkish population.MethodsOur cohort consisted of 1296 index cases and 324 affected family members. Polymerase chain reaction followed by Sanger sequencing or fragment analysis were performed to screen for the trinucleotide repeat expansions in families with a dominant inheritance pattern, as well as in sporadic cases. The expansion in the frataxin (FXN) gene was tested in all autosomal recessive cases and in sporadic cases with a compatible phenotype. Whole‐exome sequencing was applied to 251 probands, selected based on the family history, age of onset, and phenotype.ResultsMutations in known ataxia genes were identified in 30% of 1296 probands. Friedreich's ataxia was found to be the most common recessive ataxia in Turkey, followed by autosomal recessive spastic ataxia of Charlevoix–Saguenay. Spinocerebellar ataxia types 2 and 1 were the most common dominant ataxias. Whole‐exome sequencing was performed in 251 probands with an approximate diagnostic yield of 50%. Forty‐eight novel variants were found in a plethora of genes, suggesting a high heterogeneity. Variants of unknown significance were discussed in light of clinical data.ConclusionWith the large sample size recruited across the country, we consider that our results provide an accurate picture of the frequency of hereditary ataxias in Turkey. © 2021 International Parkinson and Movement Disorder Society
Self‐Monitoring via Digital Health in Weight Loss Interventions: A Systematic Review Among Adults with Overweight or Obesity
Authors: Patel Michele L. , Wakayama Lindsay N. , Bennett Gary G. 
Published: February 2021

ObjectiveSelf‐monitoring is a core component of behavioral obesity treatment, but it is unknown how digital health has been used for self‐monitoring, what engagement rates are achieved in these interventions, and how self‐monitoring and weight loss are related.MethodsThis systematic review examined digital self‐monitoring in behavioral weight loss interventions among adults with overweight or obesity. Six databases (PubMed, Embase, Scopus, PsycInfo, CINAHL, and ProQuest Dissertations & Theses) were searched for randomized controlled trials with interventions ≥ 12 weeks, weight outcomes ≥ 6 months, and outcomes on self‐monitoring engagement and their relationship to weight loss.ResultsThirty‐nine studies from 2009 to 2019 met inclusion criteria. Among the 67 interventions with digital self‐monitoring, weight was tracked in 72% of them, diet in 81%, and physical activity in 82%. Websites were the most common self‐monitoring modality, followed by mobile applications, wearables, electronic scales, and, finally, text messaging. Few interventions had digital self‐monitoring engagement rates ≥ 75% of days. Rates were higher in digital‐ than in paper‐based arms in 21 out of 34 comparisons and lower in just 2. Interventions with counseling had similar rates to standalone interventions. Greater digital self‐monitoring was linked to weight loss in 74% of occurrences.ConclusionsSelf‐monitoring via digital health is consistently associated with weight loss in behavioral obesity treatment.
Registration of ‘Yellowstone’ yellow bean
Authors: Kelly James D. , Awale Halima E. , Wiersma Andrew T. , Cichy Karen A. , Wright Evan M. 
Published: February 2021

Abstract‘Yellowstone’ yellow bean (Phaseolus vulgaris L.) (Reg. no. CV‐340, PI 695270), developed by Michigan State University AgBioResearch, was released in 2020 as a determinate, virus‐resistant cultivar with highly desirable vibrant dry seed coat color. Yellowstone was developed using the pedigree breeding method to the F3 generation followed by pure line selection for disease, agronomic, and quality traits. In 4 yr of field trials, Yellowstone yielded 2,902 kg ha−1, flowered in 41 d, and matured in 94 d on average. Plants averaged 47 cm in height, with a lodging resistance score of 1.8 and seed weight of 46 g per 100 seed. Yellowstone is well adapted to growing conditions in Michigan and produces seed with an intense yellow seed coat color under local conditions. Yellowstone is resistant to lodging, which also contributes to the avoidance of white mold. Yellowstone exhibits the top necrosis reaction to strain NL 3 of Bean common mosaic necrosis virus conditioned by the I gene. Yellowstone produces seed that exceeds industry standards for export and packaging, and canning quality was rated acceptable for the yellow bean seed class.
Crystallographic molecular replacement using an in silico‐generated search model of SARS‐CoV‐2 ORF8
Authors: Flower Thomas G. , Hurley James H. 
Published: February 2021

AbstractThe majority of crystal structures are determined by the method of molecular replacement (MR). The range of application of MR is limited mainly by the need for an accurate search model. In most cases, pre‐existing experimentally determined structures are used as search models. In favorable cases, ab initio predicted structures have yielded search models adequate for MR. The ORF8 protein of SARS‐CoV‐2 represents a challenging case for MR using an ab initio prediction because ORF8 has an all β‐sheet fold and few orthologs. We previously determined experimentally the structure of ORF8 using the single anomalous dispersion (SAD) phasing method, having been unable to find an MR solution to the crystallographic phase problem. Following a report of an accurate prediction of the ORF8 structure, we assessed whether the predicted model would have succeeded as an MR search model. A phase problem solution was found, and the resulting structure was refined, yielding structural parameters equivalent to the original experimental solution.
Social innovation within transnational flows of knowledge: The example of student mobility from Bulgaria
Authors: Glorius Birgit 
Published: February 2021

AbstractTaking the example of Bulgarians who studied abroad, this paper explores the motives and practices of graduates regarding socially innovative knowledge transfer in order to deliver social benefits for the local community. The paper shows how both stayers and returnees act within a transnational social space, which develops and deepens during and after student mobility. Engaging in socially innovative knowledge transfer is motivated by altruistic stances, by a feeling of loyalty towards the home country and by the desire to lead a meaningful life. The effectiveness of knowledge transfer is related to framing conditions such as local knowledge and the existence of social networks, notably transnational social networks. The results show that the mobility of highly qualified young adults from and to Bulgaria aligns with major European mobility regimes, with an increase of circulatory mobility processes and thus an increase of circulating knowledge and social innovation.
16.2: Invited Paper: Evaluate the Repeatability and Reliability of Heterophoria Measurement Based on Display
Authors: Zheng Fuhao , Chen Bingzhen , Huang Pingping , Mei Jianhui , Chen Yuanyuan , Chen Shuang , Hou Fan , Chen Hao , Wang Yuwen 
Published: February 2021

Objective: To design a Heterophoria Test based on Display (DHT) for clinical work, and evaluate its reliability, repeatability and validity.Methods: We recruited 30 students (9 males, 21 females, Age 24.62±2.65), from Wenzhou Medical University, randomly, excluding high myopia, strabismus, anisometropia, eye disease and history of ophthalmological surgery, to preform two experiments. The first one is that we use DHT, Von Graefe test (VG), modified Thorington test (MT), Maddox rod test (MR), and Prism‐neutralized objective cover test (POCT) to detect heterophoria for near(0.33m), middle(0.77m) and far distance(3m). We use ICC and Bland‐Altman Analysis to evaluate repeatability and reliability of DHT. The second is that we use DHT to detect the change of phoria before and after 20‐minute prism adaptation for middle distance (0.77m), to evaluate the validity of DHT “Fig. 1”.Results: In the first experiment, the result of DHT has no statistic difference with MT, MR, and POCT(p>0.05). the result of VG has statistic difference with other measurements and shows more exophoria for far distance. There is no statistic difference among DHT, MR and POCT for middle distance. Except the result of DHT and POCT, MT and MR, having no statistic difference(p>0.05). Results of other methods are different with each other(p>0.05). ICC, mean difference and 95%LoA between DHT and MT, MR, VG, POCT for different distance are shown in Table 1. In terms to repeatability, ICC for 7 times measurement are 0.99, 0.97, 0.97 for far, middle and near distance, respectively. ICC, Mean difference and 95%LoA are shown in Table 1, too. In the second experiment, Heterophoria before prism adaptation has statistic difference with that after adaptation (t=5.016, p<0.001), compared with Karpicka's study using MT to detect the heterophoria difference (1) “Fig. 2”.Conclude: DHT has fairly remarkable repeatability and reliability for far and middle distance. It is more userfriendly than MT, VG, POCT and MR. But the reliability of near measurement should improve in the future.