bluuebunny/crossref_metadata_2025_split huggingface dataset:
The World after COVID-19: the Necessity of Transition to a New Development Paradigm
Authors: Bondarenko V. M. 
Published: October 2021

This article is a continuation of a large-scale research devoted to the identification of patterns of human community development, which has been conducted by the author for many decades.Purpose: is to study the possible transformation of the world after the COVID-19 pandemic from the perspective of the need to switch to a new, crisis-free development paradigm, which is a logical continuation of the previous author's works.Methods: the study is based on the application of a complex of general scientific methods, including analysis, generalization, comparison, etc., and is based on an interdisciplinary approach. The results and conclusions of the work are based on the use of the author's methodological tools, which were formed within the framework of the general research direction.Results: the article analyzes the current state of the global world in the absence of effective ways out of the deepest crisis that has long gripped almost the entire world and has been multiplied by the COVID-19 pandemic. The study of the fundamental works of foreign scientists has shown that their main thesis is that the future of the world lies in the transition to a new development paradigm (NDP), but to fully understand it, it is necessary to develop a new scientific paradigm (NSP). Based on the use of the author's development of the NSP, it is demonstrated that the future of the world depends on the choice of a development model. The author has proved the necessity and possibility of transition to a new development paradigm based on the synchronous development and implementation of a single development strategy for the global world and each country separately.Conclusions and Relevance: after the COVID-19 pandemic, the world will change only if there is a transition to a new crisis-free paradigm for the development of the human system. The NSP developed by the author can become the tool that allows you to give a complete understanding of the NDP, and see what the world can and should be like after the coronavirus pandemic.
Tejido mamario ectópico en vulva: reporte de caso y revisión sistemática de la literatura
Authors: Buitrago-Flechas Sandra Marcela , Barrera-Latorre Sandra Johana , Morante-Caicedo Carolina 
Published: October 2021

Objetivo: reportar el caso de una paciente con diagnóstico de tejido mamario ectópico en vulva, y realizar una revisión de la literatura acerca del diagnóstico, tratamiento y pronóstico de esta condición en esta localización. Materiales y métodos: paciente de 49 años consulta por masa vulvar dolorosa a un centro privado de nivel medio de complejidad ubicado en Bogotá, Colombia. Se realizó ecografía de la lesión y posteriormente escisión quirúrgica; la histopatología mostró tejido mamario ectópico sin malignidad. Se realizó una búsqueda en las bases de datos PubMed, Embase, Cochrane, LILACS y Scielo, con las palabras clave “Vulva”, “Glándulas mamarias”, “ectópico”, “Vulva”, “Breast” y “Ectopic”, y se incluyeron reportes y series de caso de mujeres con tejido mamario en vulva confirmado por histopatología. Resultados: se identificaron 184 títulos, de los cuales 94 fueron finalmente incluidos para un total de 126 casos. El 57,9% eran tumores benignos, con un 95% en mujeres menores de 50 años; y el 42,06% eran tumores malignos, el 92 % en mujeres mayores de 50 años. El diagnóstico se realizó por clínica, con imágenes diagnósticas complementarias, marcadores tumorales e inmunohistoquímica en algunos casos. Se realizó escisión local en el 91% de los casos de patología benigna y 43% de patología maligna, siendo el método diagnóstico y terapéutico. Conclusiones: el tejido mamario ectópico en vulva debe ser considerado como parte del diagnóstico diferencial de masas a nivel vulvar con diferente pronóstico en mujeres pre y posmenopáusicas. Se requieren más estudios para una mejor caracterización de la patología y definir el tratamiento ideal en términos de recaída y supervivencia.
Urban Competitiveness in Developing Economies
Authors: Pérez Brito Antonio Emmanuel , Vázquez Carrillo Ileana del Socorro , Rodríguez Morayta Gaspar , López Jiménez Gustavo , Sabido Ponce Rafael Eduardo 
Published: October 2021

Las ciudades del mundo en desarrollo tienen diferentes niveles de competitividad y sostenibilidad a pesar de estar clasificadas en la misma categoría. Cada uno de ellos tiene antecedentes históricos, composición social, situación económica y política, herencia cultural y características geográficas diversas que han definido su lugar en el mundo global. Por esta variedad, así como por necesidades, problemas y desafíos relacionados con el desarrollo urbano, las ciudades han tenido resultados contrastantes: innovación y progreso para alguna de ellas, crisis o estancamiento para algunas otras y retroceso en otras.
O “corpo-migrante” e Bourdieu: corpo e incorporação no contexto migratório / Bourdieu and the ‘migrant-body’: embodiment in the migratory context
Authors: Ennes Marcelo Alario 
Published: October 2021

O presente artigo tem como objetivo central a análise de algumas obras de Pierre Bourdieu tendo em vista sua contribuição para o desenvolvimento de uma agenda de pesquisa em torno da ideia do “corpo-migrante”. Esta agenda visa compreender como o corpo é socialmente produzido no contexto migratório e como isto resulta nas relações sociais e de poder das quais o imigrante é parte. O artigo foi elaborado com base em (re)leituras de obras de Bourdieu com foco na ideia de incorporação e corpo e a partir de um levantamento bibliográfico por meio do qual foram identificados alguns artigos que já fazem o diálogo entre conceitos bourdieusianos e a questão migratória, e outros que tratam do corpo no contexto migratório mas sem problematizá-lo teoricamente. Como resultado, sugiro que Bourdieu nos oferece elementos suficientes para apreender e compreender o “corpo-migrante” como resultado de relações de força e poder que geram a inserção, o posicionamento e o reposicionamento de imigrantes em campos específicos em que atuam. This article sets out to analyse a number of works by Pierre Bourdieu, focusing specifically on his contribution to the development of a research agenda surrounding the ‘migrant-body.’ This agenda aims to understand how the body is socially constructed in the context of migration, and how this results in the social and power relations in which the migrant becomes embedded. The article is based on (re)reading Bourdieu’s books with a focus on his ideas of embodiment and the body. Additionally, a review of the literature enabled two groups of articles to be identified, the first comprising texts that already develop a dialogue between Bourdieu’s concepts and the topic of immigration, while the second group studies the body in the migration context without problematizing the issue theoretically. In the conclusion, I suggest that Bourdieu offers us enough elements to understand the ‘migrant-body’ as an outcome of power and social relations that generate the insertion, positioning and re-positioning of migrants within the specific fields in which they act.
PENGEMBANGAN BAHAN AJAR E-MODUL MATA KULIAH GAMBAR TEKNIK II DI PRODI PENDIDIKAN TEKNIK BANGUNAN
Authors: Andrey Andrey , Maulana Arris 
Published: October 2021

Abstrak
Penelitian ini dilatarbelakangi oleh adanya covid-19 yang menimbulkan kebosanan bagi siswa dan Berkurangnya motivasi siswa untuk mendalami materi pembelajaran khususnya pada mata kuliah Menggambar Teknik 2. Tujuan dari penelitian ini adalah untuk membuat E-Module bahan ajar mata kuliah Gambar Teknik 2 Metode penelitian yang digunakan adalah metode 4D yang penerapannya dilakukan sampai dengan proses pengembangan produk. Analisis yang dilakukan dengan menyebarkan lift dengan Likert sebagai skala yang digunakan untuk mengubahnya menjadi data. Kuesioner disebarkan kepada ahli media, ahli materi dan mahasiswa yang sudah mengikuti mata kuliah Gambar Teknik 2 sebelumnya, kemudian dihitung rata-ratanya. Hasil yang diperoleh adalah skor dengan rata-rata keseluruhan sebesar 4,3 yang termasuk kategori baik. Kesimpulan dari penelitian yang dilakukan adalah bahan ajar yang dikembangkan termasuk dalam kategori layak, dan dapat digunakan sebagai bahan ajar pada mata kuliah Gambar Teknik 2.
Kata kunci: Covid-19, Bahan ajar, E-modul, Gambar teknik 2

Abstract
This research was motivated by covid-19 which caused boredom for students and Reduced motivation from students to explore the learning material especially in the Engineering Drawing course 2. The purpose of this study is to create E-Module teaching materials for the Engineering Drawing course 2. The research method used is the 4D method, the application of which is carried out up to the product development process. Analysis which is done by spreading the lift with a Likert as the scale used for turn it into data. The questionnaire was distributed to media experts, material experts and student that already followed the previous Engineering Drawing courses 2, then calculate the average. The results obtained are a score with an overall average of 4.3 which is included good category. The conclusion of the research conducted is the teaching materials developed is included in the feasible category, and can be used as teaching material in the Engineering Drawing courses 2.
Keywords: Covid-19, Learning material, E-modul, Engineering Drawing courses 2
A New Simulation Layer Optimization and Permeability Upscaling Method for Preserving Critical Reservoir Heterogeneity
Authors: Li Dachang , Ionescu Corneliu-Liviu , Muftakhidinov Baurzhan , Haynes Byron , Yergaliyeva Bakyt 
Published: October 2021

Abstract
Running a fine grid model with 107 - 109 of cells is possible using a supercomputer with 103 - 106 of CPUs but may not be always cost-effective. The most cost-effective way is to use a coarse grid model that is much smaller but with static/dynamic profiles very close to the fine grid model. This paper proposes a new layer optimization and upscaling method with the aim for creating a consistent coarse grid model. Unlike the industry's existing layer optimization and upscaling methods, the proposed method performs layer optimization and upscaling fully integrated with the Lorenz coefficient and curves (LCC). Coarse grid layers and their permeabilities are created by minimizing the difference between fine and coarse grid LCCs. The process consists of static and dynamic optimizations. The former is measured by LCC while the latter by pressure, GOR, and water-cut. A new LCC-based permeability upscaling method is developed to preserve the fine grid multiphase flow behaviors. A satisfactory coarse grid model is achieved when both static and dynamic criteria are met. The proposed method has been successfully applied to a giant carbonate oil field in the Caspian Sea that consists of a matrix dominated platform and a fracture/karst dominated rim. Due to the field's complex geology and high H2S content (15%), a dual porosity, dual permeability compositional model has been created to model compositional sour crude flow within and between the matrix and fracture/karst features. The reservoir drive mechanisms are fluid expansion, miscible gas injection and aquifer drive. The reservoir is undersaturated and has an abnormally high initial reservoir pressure. The fine-grid static model contains 104 million cells (370×225×625×2) and the optimized upscaled coarse-grid dynamic model has 8.3 million cells (370×225×50×2). The upscaled model can be run efficiently on the company's existing HPC infrastructure with a maximum of 64 CPUs. Excellent matches of the Lorenz coefficient maps for reservoir total/zones and Lorenz curves at all wells between the fine and coarse grid models have been achieved. Matches on the dynamic variables, e.g., pressure, gas breakthrough time, and GOR growth, in all producers are within the defined acceptable tolerances. The high quality of the static and dynamic matches between the coarse- and fine-grid models confirms that the reservoir properties of the coarse-grid model is very close to the fine-grid model and can be used a base model for history matching and uncertainty analysis.
Numerical effects on the simulation of surfactant flooding for enhanced oil recovery
Authors: Akinyele Olaitan , Stephen Karl D. 
Published: October 2021

Abstract
Numerical simulation of surfactant flooding using conventional reservoir simulation models can lead to unreliable forecasts and bad decisions due to the appearance of numerical effects. The simulations give approximate solutions to systems of nonlinear partial differential equations describing the physical behavior of surfactant flooding by combining multiphase flow in porous media with surfactant transport. The approximations are made by discretization of time and space which can lead to spurious pulses or deviations in the model outcome. In this work, the black oil model was simulated using the decoupled implicit method for various conditions of reservoir scale models to investigate behaviour in comparison with the analytical solution obtained from fractional flow theory. We investigated changes to cell size and time step as well as the properties of the surfactant and how it affects miscibility and flow. The main aim of this study was to understand pulse like behavior that has been observed in the water bank to identify cause and associated conditions. We report for the first time that the pulses occur in association with the simulated surfactant water flood front and are induced by a sharp change in relative permeability as the interfacial tension changes. Pulses are diminished when the adsorption rate was within the value of 0.0002kg/kg to 0.0005kg/kg. The pulses are absent for high resolution model of 5000 cells in x direction with a typical cell size as used in well-scale models. The growth or damping of these pulses may vary from case to case but in this instance was a result of the combined impact of relative mobility, numerical dispersion, interfacial tension and miscibility. Oil recovery under the numerical problems reduced the performance of the flood, due to large amounts of pulses produced. Thus, it is important to improve existing models and use appropriate guidelines to stop oscillations and remove errors.
Thru-Hole Epitaxy: Is Remote Epitaxy Really Remote?
Authors: Jang Dongsoo , Ahn Chulwoo , Lee Youngjun , Lee Seungjun , Lee Hyunkyu , Kim Donghoi , Kwon Young-Kyun , Choi Jaewu , Kim Chinkyo 
Published: October 2021

Abstract
The remote epitaxy was originally proposed to grow a film, which is not in contact but crystallographically aligned with a substrate and easily detachable due to a van der Waals material as a space layer. Here we show that the claimed remote epitaxy is more likely to be nonremote `thru-hole' epitaxy. On a substrate with thick and symmetrically incompatible van der Waals space layer or even with a three-dimensional amorphous oxide film in-between, we demonstratively grew GaN domains through thru-holes via connectedness-initiated epitaxial lateral overgrowth, not only readily detachable but also crystallographically aligned with a substrate. Our proposed nonremote thru-hole epitaxy, which is embarrassingly straightforward and undemanding, can provide wider applicability of the benefits known to be only available by the claimed remote epitaxy.
Integrated immune networks in SARS-CoV-2 infected pregnant women reveal differential NK cell and unconventional T cell activation
Authors: Kedzierska Katherine , Habel Jennifer , Chua Brendon , Kedzierski Lukasz , Selva Kevin , Damelang Timon , Haycroft Ebene , Nguyen Thi , Koay Hui-Fern , Nicholson Suellen , McQuilten Hayley , Jia Xiaoxiao , Allen Lilith , Hensen Luca , Zhang Wuji , de Sandt Carolien van , Neil Jessica , Amanat Fatima , Krammer Florian , Wragg Kathleen , Juno Jennifer , Wheatley Adam , Tan Hyon-Xhi , Pell Gabrielle , Audsley Jennifer , Thevarajan Irani , Denholm Justin , Subbarao Kanta , Godfrey Dale , Cheng Allen , Tong Steven , Bond Katherine , Williamson Deborah , James Fiona , Holmes Natasha , Smibert Olivia , Trubiona Jason , Gordon Claire , Chung Amy , Whitehead Clare , Kent Stephen , Lappas Martha , Rowntree Louise 
Published: October 2021

Abstract
Although pregnancy poses a greater risk for severe COVID-19, the underlying immunological changes associated with SARS-CoV-2 infection during pregnancy are poorly understood. We defined immune responses to SARS-CoV-2 in pregnant and non-pregnant women during acute and convalescent COVID-19 up to 258 days post symptom onset, quantifying 217 immunological parameters. Additionally, matched maternal and cord blood were collected from COVID-19 convalescent pregnancies. Although serological responses to SARS-CoV-2 were similar in pregnant and non-pregnant women, cellular immune analyses revealed marked differences in key NK cell and unconventional T cell responses during COVID-19 in pregnant women. While NK, γδ T cells and MAIT cells displayed pre-activated phenotypes in healthy pregnant women when compared to non-pregnant age-matched women, activation profiles of these pre-activated NK and unconventional T cells remained unchanged at acute and convalescent COVID-19 in pregnancy. Conversely, activation dynamics of NK and unconventional T cells were prototypical in non-pregnant women in COVID-19. In contrast, activation of αβ CD4+ and CD8+ T cells, T follicular helper cells and antibody-secreting cells was similar in pregnant and non-pregnant women with COVID-19. Elevated levels of IL-1β, IFN-γ, IL-8, IL-18 and IL-33 were also found in pregnant women in their healthy state, and these cytokine levels remained elevated during acute and convalescent COVID-19. Collectively, our study provides the first comprehensive map of longitudinal immunological responses to SARS-CoV-2 infection in pregnant women, providing insights into patient management and education during COVID-19 pregnancy.
Safety and Efficacy of Two Doses of Tandospirone Citrate for Generalized Anxiety Disorder: A Multicenter Randomized Controlled Trial
Authors: Li Qingwei , Zhang Haiyin , Lin Guozhen , Shi Shenxun , Zhang Yingli , Ji Jianlin , Yang Lipeng , Li Jun , Li Xiuli , Yao Jun , Wu Wenyuan 
Published: October 2021

Abstract
Background

This study aimed to determine the safety and efficacy of different doses of tandospirone to treat generalized anxiety disorder (GAD).
Methods

This parallel randomized controlled trial involved patients with GAD from eight centers in China between 01/2012 and 09/2018. Patients were randomly assigned to 60 mg/day and 30 mg/day groups. The primary endpoint was the overall response rate at the end of week 6. The secondary endpoints included significant response rate, change in Hamilton Anxiety Scale (HAMA) total score, HAMA subscale score, Hamilton Depression Scale-17 (HAMD-17), and adverse drug reactions.
Results

No significant difference was found in the overall response rate (65.7% vs 58.4%, P > 0.05) between 60 mg/day and 30 mg/day groups. The significant response rate (34.3% vs 22.6%, P = 0.032) was better in the 60 mg/day group. The reduction in HAMA total score, somatic anxiety factor, cardiovascular symptom factor, gastrointestinal symptom factor, and HAMD-17 score were better in the 60 mg/day group (all P < 0.05). The incidence of dizziness and gastrointestinal reactions of the 60 mg/day group was higher than that of the 30 mg/day group. However, there was no significant difference in the proportion of withdrawal due to adverse events.
Conclusions

For GAD treatment, the overall response rate of high-dose tandospirone was similar to that of low-dose tandospirone. The safety in the two groups was tolerable. Patients with good compliance might benefit from a high-dose regimen.
Trial registration:

The trial registration no. was NCT01614041(07/06/2012).
ABCD Approach At The #7119 Center, Telephone Triage System in Tokyo, Japan; A Retrospective Cohort Study
Authors: Sakurai Atsushi , Ohta Sachiko , Oda Jun , Muguruma Takashi , Abe Takeru , Morimura Naoto 
Published: October 2021

Abstract
Background
The algorithm and protocol of the #7119 telephone triage in Tokyo, Japan, had been originally established and consists of three steps. In this study, we investigated the outcome of patients treated with physiological abnormality (ABCD approach: A, airway; B, breathing; C, circulation, and D, dysfunction of central nervous system) in step 2 during the #7119 telephone triage and clarified the meaning of evaluation of this approach.
Methods
We retrospectively reviewed data from the Tokyo Fire Department from January 2016 to December 2017. Almost all the patients triaged using the ABCD approach were transferred to the hospital by ambulance and assigned severity by a physician. We divided patients into groups with combinations of 15 patterns including A, B, C, D, AB, AC, AD, BC, BD, CD, ABC, ABD, ACD, BCD, and ABCD. We compared the proportion of severe cases in each group using a Fisher's exact test, followed by residual analysis..
Results
We analyzed 13,793 cases triaged using the ABCD approach. In this analysis, 31% of total cases were assessed as severe cases. Groupwise analysis showed that the proportion of severe cases was significantly higher in the AD, BC, CD, ABD, and ABCD groups, while it was significantly less in the C and AB groups than in the total cases.
Conclusion
At the #7119 telephone triage, we can pick up the severe cases by the ABCD approach. This may contribute to the prompt transportation of severe patients to hospitals by dispatching ambulance cars using the #7119 telephone triage methods.
Study on the Correlation Between Homocysteine-related Dietary Patterns and Gestational Diabetes Mellitus Based on Reduced-rank Regression Analysis
Authors: Liu Yu-hong , Lu Ling-peng , Yi Min-hui , Shen Chun-yan , Wang Si-yu , Lu Gu-qin , Wu Hui 
Published: October 2021

Abstract
Background: This study aimed to evaluate the association between homocysteine-related dietary patterns and gestational diabetes mellitus. Methods: A total of 488 pregnant women at 24–28 weeks of gestation between January 2019 and December 2020 were included. Demographic characteristics, dietary intake, and multivitamin supplement intake information were collected using a food frequency questionnaire (FFQ); fasting venous blood samples were collected for serum index detection. Serum homocysteine (Hcy), folic acid, and B12 were selected as response variables, and hyperhomocysteinemia (hHcy)-related dietary patterns were extracted using the descending rank regression method. The relationship between the score of hHcy-related dietary patterns and GDM was analyzed using a multivariate logistic regression model. Results: Three hHcy-related dietary patterns were extracted. Only mode 2 had a positive and significant relationship with the risk of developing GDM. After adjusting for confounding factors, the risk of GDM was significantly increased in the highest quartile array compared with the lowest quartile of the pattern (OR=2.96, 95% Confidence Interval: 0.939–9.356, P=0.004). There was no significant correlation between dietary pattern 1 and GDM risk (P>0.05). Conclusions: Homocysteine-related dietary patterns were positively associated with gestational diabetes mellitus. Adjusting dietary patterns may contribute to the intervention and prevention of GDM.