bluuebunny/crossref_metadata_2025_split huggingface dataset:
Moradas do belo na educação
Authors: Hardt Lúcia Schneider 
Published: April 2021

O artigo destaca a reflexão sobre o belo, abordado no campo filosófico, para pensar os seus possíveis desdobramentos pedagógicos. Ancorado em vários autores, por vezes até dissonantes entre si, o artigo pretendeu priorizar o exercício de uma prática ainda necessária: superar o pensamento dualista, em que as lentes estariam focadas em destacar um dos lados para extinguir os demais. A morada do belo depende de muitas perspectivas, não será possível aprisioná-lo em um só lugar, conceito ou autor. O belo movido pela arte, pelo trágico e pela vida escapa sempre de apressadas conclusões e quer nos ver em movimento para sofisticar ainda mais as possíveis expressões deste existir humano. O destino da reflexão é o campo da educação, com o intuito de devolver a ela o direito a pensar e fazer o belo se materializar nas inúmeras possibilidades de formação humana.Palavras-chave: Belo. Filosofia da Educação. PedagogiaThe homes of beauty in educationABSTRACT The article highlights the reflection on the beauty, approached in the philosophical field, to think about its possible pedagogical consequences. Anchored by several authors, sometimes even dissonant with each other, the article intended to prioritize the exercise of a still necessary practice: overcoming dualistic thinking, where lenses would be focused on highlighting one side to extinguish the others. The home of beauty depends on many perspectives, it will not be possible to imprison it in one place, concept or author. Beauty, moved by art, tragic and life, always escapes hasty conclusions and wants to see us moving to further sophisticate the possible expressions of this human existence. The fate of reflection is the field of education in order to return to it the right to think and make the beauty materialize in the countless possibilities of human formation.Keywords: Beauty. Philosophy of Education. Pedagogy,Moradas de la belleza en la educaciónRESUMENEl artículo destaca la reflexión sobre lo bello, abordado en el campo filosófico, para pensar en sus posibles consecuencias pedagógicas. Anclados por varios autores, a veces incluso disonantes entre sí, el artículo pretendía priorizar el ejercicio de una práctica aún necesaria: superar el pensamiento dualista, donde las lentes se centrarían en resaltar un lado para extinguir los otros. La morada de la belleza depende de muchas perspectivas, no será posible encarcelarla en un solo lugar, concepto o autor. La belleza, movida por la arte, lo trágico y la vida, siempre escapa a conclusiones apresuradas y quiere vernos en movimiento para sofisticar aún más las posibles expresiones de esta existencia humana. El destino de la reflexión es el campo de la educación para devolverle el derecho a pensar y hacer que lo bello se materialice en las innumerables posibilidades de la formación humana.Palabras clave: Bello. Filosofía de la Educación. Pedagogía.
Bölgesel Kalkınmada Yerel Yönetimlerin Rolü: Konya Örneği
Authors: ARSLAN Erdal , ÇETİNER Tuğçe 
Published: April 2021

Amaç: Bu çalışma ile kalkınmada yerel yönetimlerin rolünü ortaya koymak, Konya’nın yerel kalkınmasına fayda sağlamak ve yeni kalkınma stratejilerinin geliştirilmesinde yararlanılabilecek örnek bir çalışma gerçekleştirerek literatüre katkıda bulunmak hedeflenmiştir.
Tasarım/Yöntem: Araştırmada tesadüfi örneklem yöntemlerden biri olan kota örneklem yöntemiyle belirlenen 150 katılımcıya ulaşılmış ve 100 katılımcıdan geri dönüş sağlanarak anket çalışması yapılmıştır. Anket sorularında 5’li Likert ölçeği kullanılmıştır. Ulaşılan sonuçlar SPSS 15.0 programı ile analiz edilmiştir.
Bulgular: Analiz sonuçlarına bakılarak, kalkınmada yerel aktörlerin üstlendikleri rollerin ve karşılaşılan sorunların birçok noktada benzerlik gösterdiğini söylemek mümkündür. Yerelde hizmet sağlamaları nedeniyle bölge koşullarına hâkim olan yerel aktörlerin birçoğu kaynak sıkıntısı çekmekte ve ortaklaşa çalışmada zorluklar yaşamaktadır.
Sınırlılıklar: Örneklemin yalnızca Konya ilindeki yerel aktörlerden oluşması, anket sorularının Konya ilinin kalkınma düzeyine ve kalkınma sorunlarının nedenlerini ortaya koymaya yönelik olarak hazırlanması çalışmanın sınırlılıklarıdır.
Özgünlük/Değer: Konuyla ilgili literatür taraması yapılmış ve benzer birkaç çalışmaya ulaşılmış olmasına rağmen Konya ili özelinde bir araştırmaya rastlanmamıştır. Bu nedenle konu özgün bir değer taşımaktadır. Ayrıca kalkınma ve yerel yönetim konuları üzerine hazırlanmış multidisipliner bir araştırma olması da çalışmanın değerini arttırmaktadır.
Immune Responses in an Infant with Congenital Heart Disease and Severe COVID-19&nbsp;
Authors: Licciardi Paul , Wurzel Danielle , Neeland Melanie , Anderson Jeremy , Abo Yara-Natalie , Do Lien Anh Ha , Donato Celeste , Bines Julie , Toh Zheng Quan , Higgins Rachel , Jalali Sedi , Cole Theresa , Subbarao Kanta , McMinn Alissa , Dohle Kate , Haeusler Gabrielle , McNab Sarah , Alafaci Annette , Overmars Isabella , Clifford Vanessa , Lee Lai-Yang , Daly Andrew , Buttery Jim , Bryant Penelope , Burgner David , Steer Andrew , Tosif Shidan , Konstantinov Igor , Duke Trevor , Pellicci Dan , Crawford Nigel 
Published: April 2021

Abstract
Children have lower hospitalisation and mortality rates for coronavirus disease-2019 (COVID-19) than adults; however, younger children (<4 years of age)1 may develop more severe disease than older children. To date, the immune correlates of severe COVID-19 in young children have been poorly characterized. We report the kinetics of immune responses in relation to clinical and virological features in an infant with acute severe COVID-19. Systemic cellular and cytokine profiling showed initial increase in neutrophils and monocytes with depletion of lymphoid cell populations (particularly CD8+ T and NK cells) and elevated inflammatory cytokines. Expansion of memory CD4+T (but not CD8+T) cells occurred over time, with predominant Th2 bias. Marked activation of T cell populations observed during the acute infection gradually resolved as the child recovered. Significant in vitro activation of T-cell populations and robust cytokine production, in response to inactivated SARS-CoV-2 stimulation, was observed 3 months after infection indicating durable, long-lived cellular immune memory.
Diverse key nitrogen cycling genes nifH, nirS and nosZ associated with mangrove rhizosphere soils of Pichavaram as revealed by culture dependent and independent analysis.
Authors: Viswanathan Baskaran , ramalingam Prabavathy vaiyapuri 
Published: April 2021

Abstract
PCR-DGGE and culturable diversity analysis of nitrogenase gene nifH and denitrifying genes nirS and nosZ affiliated with heterotrophic and unculturable bacterial communities associated with rhizosphere of A. marina, R. mucronata, S. maritima and S. brachiata revealed the dominance of gammaproteobacterial community across the rhizospheres. Sequence analysis of the PCR-DGGE profiles of nifH genes clustered to unculturables, while majority of the nirS and nosZ genes clustered with unculturables with few culturable groups viz., Pseudomonas sp. and Halomonas sp. Culturable analysis reflected the dominance of Gammaproteobacteria as both nitrogen fixers and denitrifiers while other groups like Firmicutes and Alphaproteobacteria were very less represented among nitrogen fixers, and denitrifiers respectively. A total of 16 different genera were identified as nitrogen fixers and denitrifiers. BOX-PCR analysis of Mangovibacter, Vibrio, Bacillus and Catenococcus isolated in this study showed varied fingerprinting patterns compared to their respective positive controls reported earlier from this ecosystem, indicating they may be novel.
Study the impact of A nanomixture of carbon black and clay on the mechanical properties of A series of irradiated natural rubber/ butyl rubber blend
Authors: Alshangiti Dalal 
Published: April 2021

Abstract
A series of natural rubber/ butyl rubber NR/IIR blend loaded with N660 carbon black CB and triethoxy vinyl silane treated clay nano particles (TCNP) were prepared using gamma irradiation in the presence of polyfunctional monomer, trimethylolpropane triacrylate (TMPTA). The effect of incorporating different content of N660 carbon black and 5 part per hundred of rubber (phr) of treated clay on the mechanical properties of the prepared nano composites have been investigated. The additions of TCNP into CB/ rubber composites markedly increase their tensile strength due to the increase of the cross-link density. These results indicated that the TCNP may be enclosed or trapped in the occluded structure of CB. The effect of CB and TCNP content on the tensile strength (σ), elongation at break (εb %) and modulus of elasticity (E, MPa) of natural rubber/ butyl rubber NR/IIR blend have been investigated. The incorporation of 5 phr of TCNP into 30 phr carbon black loaded NR/ IIR composites results in the increased tensile strength value by about 60%. Finally, theoretical models were used to interpret the experimental results.
Wood carbon electrode in microbial fuel cell enhances chromium reduction and bioelectricity generation
Authors: Ni Hongyuhang , Khan Aman , Yang Zi , Gong Yuxin , Ali Gohar , Liu Pu , Chen Fengjuan , Li Xiangkai 
Published: April 2021

Abstract
Microbial Fuel Cell (MFC) remediate hexavalent chromium (Cr(VI)) in wastewater, but inefficient removal for wide scale. In this study, a wood carbon (WC) electrode was introduce in MFC to analyzed the Cr(VI) remediation mechanism and effect of WC on it. The results show that the Cr(VI) was completely removed with WC electrode as compare to the carbon cloth (31.12 ± 0.31%) and carbon felt (34.83% ± 0.12) within 48 hours. The maximum power density of the WC electrode was 62.59 ± 0.27 mW m− 2. Here in, WC might a good choice with a three-dimensional porous structure for Cr(VI) contaminated wastewater treatment and electricity generation in MFC.
Generation means analysis of traits related to lodging using two crosses of durum×emmer wheat
Authors: Mohammadi Majid , Mirlohi Aghafakhr , Majidi Mohammad Mahdi , Khedri Zahra , Rezaei Vahid 
Published: April 2021

Abstract
Lodging is one of the most important factors that affect wheat final yield. Emmer is a likely gene source to improve durum wheat; however, it is highly susceptible to lodging. The genetic studies of traits related to lodging in crosses of durum×emmer remains largely understudied. Here, we used progenies (six generations) derived from two crosses of durum×emmer in a generation means analysis (GMA) to determine gene action, inheritance, and genetic gain from selection in respect to plant height and its related traits. The results indicated that lodging resistance was significantly and negatively correlated with plant height and positively correlated with grain yield and mainly influenced by stem diameter. GMA results indicated that epistasis did not play an essential role in the genetic control of lodging related traits and almost the major portion of the genetic variation in these crosses resulted from additive gene actions. Also for all of the studied traits, the additive variance was higher than the dominance one. Narrow sense heritability was higher than 0.60 for most of the traits, and the genetic gain after one cycle of selection was positive for plant height and its components in both crosses. It was found that, selection in early generations may result in simultaneous reduction of plant height and increased stem diameter to improve lodging resistance in durum×emmer crossings.
Root K affinity drivers and photosynthetic characteristics in response to low potassium stress in K high-efficiency vegetable soybean
Authors: Liu Changkai , Wang Xue , Tu Bingjie , Li Yansheng , Chen Heng , Zhang Qiuying , Liu Xiaobing 
Published: April 2021

Abstract
Aims Vegetable soybean is highly demanded on potassium (K) application. Significant variations of K absorption and utilization exist in vegetable soybean. This study aim at exploring mechanisms of K absorption and utilization of high-efficiency in vegetable soybean by studying the characteristics of root K affinity-associated drivers and photosynthesis in vegetable soybean (edamame) (Glycine max (L.) Merr.).Methods Pot and hydroponic experiments were carried out to examine the characteristics of root K affinity-associated drivers and photosynthesis in vegetable soybean genotypes with different K efficiency. Two K high-efficiency vegetable soybean genotypes and two K low-efficiency genotypes were investigated in low K and normal K conditions. Results The root of K high-efficiency genotypes had a higher K+ affinity associated with higher maximum K+ uptake rate (Imax), but lower Michaelis constant for K+ absorption (Km) and lower compensation concentration for K+ uptake (Cmin). Seedlings of K high-efficiency genotypes also had higher root vigor (TTC reduction method) and greater absorbing activity (methylene blue method), especially in the low K condition. Besides, the root bleeding-sap rate per root length and K upward fluxes rate per root length of K high-efficiency genotypes in beginning seed stage were consistently higher than that of K low-efficiency genotypes. The root of K high-efficiency vegetable soybean genotypes exhibits K+ high-affinity and driving advantages. Photosynthetic parameters of K high-efficiency vegetable soybean genotypes were less affected by low K stress. Low K stress decreased the net photosynthetic rate of K high-efficiency genotypes by 6.1~6.9%, while that of K low-efficiency genotypes decreased by 10.9~15.7%. The higher Chl a/b ratio with enhanced relative content of Chl a in response to low K stress might be an adapted mechanism for K high-efficiency genotypes to maintain photosynthetic capacity.Conclusion Stronger root K affinity drivers associated with photosynthetic adaptability to low potassium stress are the key factors in determining the K high-efficiency of vegetable soybeans.
Assesment Of Protein Profile In Vitreus Samples Of Patients With Age-Related Macular Degeneration By Proteomic Approaches
Authors: Köse Hamza , Özkan Berna , Kanlı Aylin , Akpınar Gürler , Kasap Murat , Karabaş Levent 
Published: April 2021

Abstract
Background: To investigate the protein content in patients with age-related macular degeneration (AMD) with the aim of revealing the pathogenesis of the disease. Methods: Two groups were formed: 13 patients as the AMD group and 11 patients as the healthy control group. Vitreous samples were taken from both groups under sterile conditions and sent to the proteomics laboratory for proteomics analysis. In this study, we evaluated the proteome of vitreous samples of AMD and control groups using two-dimensional gel electrophoresis (2DE) coupled with MALDI-TOF/TOF.Results: We detected 11 proteins differentially regulated in the vitreous of AMD patients relative to healthy controls. The only protein that was up-regulated was Apolipoprotein E. We observed that Alpha 1-acid glycoprotein (AAG), Leucine-rich alpha-2-glycoprotein (LRG-1), Alpha-2-HS-glycoprotein, Haptoglobin, Alpha-Crystalline A Chain, Alpha- Crystalline B Chain, Immunoglobulin kappa constant, Beta-crystallin B2, Beta-crystallin A3, Beta-crystallin S levels were significantly decreased in patients with AMD. Conclusion: The detected proteins are related to biological regulation, retinal protection, and regulation of inflammation and angiogenesis processes. We believe that investigating these proteins will help to reveal the pathological mechanisms of AMD.
Knowledge and awareness regarding facemasks among medical professionals in a COVID dedicated hospital – Time for introspection and system strengthening.
Authors: Aggarwal Sulakshna , Bains Lovenish , Mishra Anurag , Dabaas Aashima , Goel Madhav , Perween Aiman Afsar 
Published: April 2021

Abstract
Background- There is a limited literature especially in India on the awareness regarding facemasks among medical professionals. Therefore the aim of the study is to assess the awareness, practices followed and problems faced in using different types of facemasks among medical professionals in a COVID dedicated hospital.Methodology- An e-survey via was conducted among medical professionals working in a tertiary care (COVID dedicated) hospital of North-India. The survey asked for the general demographic details, knowledge and awareness on facemask use, quality and various problems faced on regular or prolonged use, sanitization / disposal and recommendations to infected and non- infected people in community. Results- Survey was sent to around 368 medical professionals out of which a total of 150 participants completed the survey giving an overall response rate of 40.8%. The mean score was 9.8 +/- 2.375 out of 21 giving an overall correct rate of 46.67%. 38% and 31.33% participants knew the correct recommendations of facemasks to infected and non-infected people in the community respectively, Only 4.67% knew the correct sanitization procedures, 84% and 69.33% participants reported problems of discomfort on face and sweat issues respectively while 48.7% of the population felt some amount of breathlessness within 1-3 hours with N-95/FFP2 masks. Discussion- Awareness in this part of the world was low as compared to the western compared to countries (46.67%) which increases significantly with years of experience(p<0.001), however no such correlation of knowledge score with discipline of medical professionals was found. Since, it is the young medical force which is at the forefront to tackle the menace, therefore, institute should provide regular training and knowledge up gradation about the facemasks and adequate and accurate information needs to be disseminated to younger medical professionals via social media to prevent them from the risk of infection.
Distinct RPA domains promote recruitment and the helicase-nuclease activities of Dna2
Authors: Acharya Ananya , Kasaciunaite Kristina , Göse Martin , Kissling Vera , Guérois Raphaël , Seidel Ralf , Cejka Petr 
Published: April 2021

Abstract
The Dna2 helicase-nuclease functions in concert with the replication protein A (RPA) in DNA double-strand break repair. Using ensemble and single-molecule biochemistry, coupled with structure modeling, we demonstrate that the stimulation of S. cerevisiae Dna2 by RPA is not a simple consequence of Dna2 recruitment to single-stranded DNA. The large RPA subunit Rfa1 alone can promote the Dna2 nuclease activity, and we identified mutations in a helix embedded in the N-terminal domain of Rfa1 that specifically disrupt this capacity. The same RPA mutant is instead fully functional to recruit Dna2 and promote its helicase activity. Furthermore, we found residues located on the outside of the central DNA-binding OB-fold domain Rfa1-A, which are required to promote the Dna2 motor activity. Our experiments thus unexpectedly demonstrate that different domains of Rfa1 regulate Dna2 recruitment, and its nuclease and helicase activities. Consequently, the identified separation-of-function RPA variants are compromised to stimulate Dna2 in the processing of DNA breaks. The results explain phenotypes of replication-proficient but radiation-sensitive RPA mutants and illustrate the unprecedented functional interplay of RPA and Dna2.
Understanding the Factors that Affect the Appropriateness of Rheumatology Referrals
Authors: Broek-Altenburg Eline Van Den , Atherly Adam , Cheney Nick , Fama Teresa 
Published: April 2021

Abstract
Background: Reducing inappropriate referrals to specialists is a challenge for the healthcare system as it seeks to transition from volume to value-based healthcare. Given the projection of a severe shortage of rheumatologists in the near future, innovative strategies to decrease demand for rheumatology services may prove more fruitful than increasing the supply of rheumatologists. Efforts to increase appropriate utilization through reductions in capacity may have the unintended consequence of reducing appropriate care as well. This highlights the challenges in increasing the appropriate use of high cost services as the health system transitions to value based care. The objective of this study was to analyze factors affecting appropriateness of rheumatology services.Methods: This was a cross-sectional study of patients receiving Rheumatology services between November 2013 and October 2019. We used a proxy for “appropriateness”: whether or not there was any follow-up care after the first appointment. Results from regression analysis and physicians’ chart reviews were compared using an inter-rater reliability measure (kappa). Data was drawn from the EHR 2013-2019. Results: We found that inappropriate referrals increased 14.3% when a new rheumatologist was hired, which increased to 14.8% after wash-out period of 6 months; 15.7% after 12 months; 15.5% after 18 months and 16.7% after 18 months. Other factors influencing appropriateness of referrals included severity of disease, gender and insurance type, but not specialty of referring provider. Conclusions: Given the projection of a severe shortage of rheumatologists in the near future, innovative strategies to decrease demand for rheumatology services may prove more fruitful than increasing the supply of rheumatologists. Innovative strategies to decrease demand for rheumatology services may prove more fruitful than increasing the supply of rheumatologists. These findings may apply to other specialties as well. This study is relevant for health care systems that are implementing value-based payment models aimed at reducing inappropriate care.