bluuebunny/crossref_metadata_2025_split huggingface dataset:
An implicit integration scheme with consistent tangent modulus for Leblond’s model of transformation-induced plasticity in steels
Authors: Wölfle Christoph Hubertus , Krempaszky Christian , Werner Ewald 
Published: December 2021

AbstractThermomechanical treatments involving solid-state phase transformations play an important role for the manufacturing of functional and reliable components in many engineering applications. Accordingly, numerical investigation and optimization of such processes require considering thermoelastoplasticity under the influence of ongoing transformations and in particular the impact of transformation-induced plasticity (TRIP). While a number of elaborate plasticity models have been proposed for the description of TRIP, none of them seem to have received much prevalence in applications due to their complexity or hard to determine model parameters. Instead, the overwhelming majority of applied research either relies on simplistic formulations dating back to early phenomenological approaches or neglects TRIP altogether. In this work, we therefore provide an accessible, straightforward and easy-to-implement solution scheme for the TRIP model proposed by Leblond et al. which, despite being widely recognized, is hardly ever employed in full form. Specifically, we employ implicit backward-Euler integration and an elastic–plastic operator split approach to update the stresses in order to obtain a simple and concise algorithm for which we then derive the corresponding consistent tangent modulus. Furthermore, the work contains an application of the solution scheme to a symmetrically cooled plate and an in-depth discussion of the influence of TRIP by means of this tractable numerical example. Specifically, we highlight the discrepancies arising in transient and residual stresses and strains compared to the conventional $$J_2$$

J
2

-plasticity approach where the phase transformation is accounted for merely by adapting the yield strength of the compound.
Cross ratios and cubulations of hyperbolic groups
Authors: Beyrer Jonas , Fioravanti Elia 
Published: December 2021

AbstractMany geometric structures associated to surface groups can be encoded in terms of invariant cross ratios on their circle at infinity; examples include points of Teichmüller space, Hitchin representations and geodesic currents. We add to this picture by studying cocompact cubulations of arbitrary Gromov hyperbolic groups G. Under weak assumptions, we show that the space of cubulations of G naturally injects into the space of G-invariant cross ratios on the Gromov boundary $$\partial _{\infty }G$$

∂
∞

G

. A consequence of our results is that essential, hyperplane-essential, cocompact cubulations of hyperbolic groups are length-spectrum rigid, i.e. they are fully determined by their length function. This is the optimal length-spectrum rigidity result for cubulations of hyperbolic groups, as we demonstrate with some examples. In the hyperbolic setting, this constitutes a strong improvement on our previous work [4]. Along the way, we describe the relationship between the Roller boundary of a $$\mathrm{CAT(0)}$$

CAT
(
0
)

cube complex, its Gromov boundary and—in the non-hyperbolic case—the contracting boundary of Charney and Sultan. All our results hold for cube complexes with variable edge lengths.
Selective Valve Removal for Melody Valve Endocarditis: Practice Variations in a Multicenter Experience
Authors: Davtyan Arpine , Guyon Peter W. , El-Sabrout Hannah R. , Ponder Reid , Ramchandar Nanda , Weber Rachel , Zayed Wagih , Ratnayaka Kanishka , Nigro John J. , Moore John W. , Bauser-Heaton Holly , Alshawabkeh Laith , Reeves Ryan R. , Levi Daniel , Aboulhosn Jamil , Justino Henri , Bradley John , El-Said Howaida G. 
Published: December 2021

AbstractGuidelines for management of Melody transcatheter pulmonary valve (TPV) infective endocarditis (IE) are lacking. We aimed to identify factors associated with surgical valve removal versus antimicrobial therapy in Melody TPV IE. Multicenter retrospective analysis of all patients receiving Melody TPV from 10/2010 to 3/2019 was performed to identify cases of IE. Surgical explants versus non-surgical cases were compared. Of the 663 Melody TPV implants, there were 66 cases of IE in 59 patients (59/663, 8.8%). 39/66 (59%) were treated with IV antimicrobials and 27/66(41%) underwent valve explantation. 26/59 patients (44%) were treated medically without explantation or recurrence with average follow-up time of 3.5 years (range:1–9). 32% of Streptococcus cases, 53% of MSSA, and all MRSA cases were explanted. 2 of the 4 deaths had MSSA. CART analysis demonstrated two important parameters associated with explantation: a peak echo gradient ≥ 47 mmHg at IE diagnosis(OR 10.6, p < 0.001) and a peak echo gradient increase of > 24 mmHg compared to baseline (OR 6.7, p = 0.01). Rates of explantation varied by institution (27 to 64%). In our multicenter experience, 44% of patients with Melody IE were successfully medically treated without valve explantation or recurrence. The degree of valve stenosis at time of IE diagnosis was strongly associated with explantation. Rates of explantation varied significantly among the institutions.
Finite-Dimensionality of Tempered Random Uniform Attractors
Authors: Cui Hongyong , Cunha Arthur C. , Langa José A. 
Published: December 2021

AbstractFinite-dimensional attractors play an important role in finite-dimensional reduction of PDEs in mathematical modelization and numerical simulations. For non-autonomous random dynamical systems, Cui and Langa (J Differ Equ, 263:1225–1268, 2017) developed a random uniform attractor as a minimal compact random set which provides a certain description of the forward dynamics of the underlying system by forward attraction in probability. In this paper, we study the conditions that ensure a random uniform attractor to have finite fractal dimension. Two main criteria are given, one by a smoothing property and the other by a squeezing property of the system, and neither of the two implies the other. The upper bound of the fractal dimension consists of two parts: the fractal dimension of the symbol space plus a number arising from the smoothing/squeezing property. As an illustrative application, the random uniform attractor of a stochastic reaction–diffusion equation with scalar additive noise is studied, for which the finite-dimensionality in $$L^2$$

L
2

is established by the squeezing approach and that in $$H_0^1$$

H
0
1

by the smoothing framework. In addition, a random absorbing set that absorbs itself after a deterministic period of time is also constructed.
Cost-effectiveness of noninvasive telemedical interventional management in patients with heart failure: health economic analysis of the TIM-HF2 trial
Authors: Sydow Hanna , Prescher Sandra , Koehler Friedrich , Koehler Kerstin , Dorenkamp Marc , Spethmann Sebastian , Westerhoff Benjamin , Wagner Christoph J. , Liersch Sebastian , Rebscher Herbert , Wobbe-Ribinski Stefanie , Rindfleisch Heike , Müller-Riemenschneider Falk , Willich Stefan N. , Reinhold Thomas 
Published: December 2021

Abstract
Background
Noninvasive remote patient management (RPM) in patients with heart failure (HF) has been shown to reduce the days lost due to unplanned cardiovascular hospital admissions and all-cause mortality in the Telemedical Interventional Management in Heart Failure II trial (TIM-HF2). The health economic implications of these findings are the focus of the present analyses from the payer perspective.

Methods and results
A total of 1538 participants of the TIM-HF2 randomized controlled trial were assigned to the RPM and Usual Care group. Health claims data were available for 1450 patients (n = 715 RPM group, n = 735 Usual Care group), which represents 94.3% of the original TIM-HF2 patient population, were linked to primary data from the study documentation and evaluated in terms of the health care cost, total cost (accounting for intervention costs), costs per day alive and out of hospital (DAOH), and cost per quality-adjusted life year (QALY). The average health care costs per patient year amounted to € 14,412 (95% CI 13,284–15,539) in the RPM group and € 17,537 (95% CI 16,179–18,894) in the UC group. RPM led to cost savings of € 3125 per patient year (p = 0.001). After including the intervention costs, a cost saving of € 1758 per patient year remained (p = 0.048).

Conclusion
The additional noninvasive telemedical interventional management in patients with HF was cost-effective compared to standard care alone, since such intervention was associated with overall cost savings and superior clinical effectiveness.

Graphical abstract
Cluster capacity functionals and isomorphism theorems for Gaussian free fields
Authors: Drewitz Alexander , Prévost Alexis , Rodriguez Pierre-François 
Published: December 2021

AbstractWe investigate level sets of the Gaussian free field on continuous transient metric graphs$$\widetilde{{\mathcal {G}}}$$G~and study the capacity of its level set clusters. We prove, without any further assumption on the base graph$${\mathcal {G}}$$G, that the capacity of sign clusters on$$\widetilde{{\mathcal {G}}}$$G~is finite almost surely. This leads to a new and effective criterion to determine whether the sign clusters of the free field on$$\widetilde{{\mathcal {G}}}$$G~are bounded or not. It also elucidates why the critical parameter for percolation of level sets on $$\widetilde{{\mathcal {G}}}$$G~vanishes in most instances in the massless case and establishes the continuity of this phase transition in a wide range of cases, including all vertex-transitive graphs. When the sign clusters on$$\widetilde{{\mathcal {G}}}$$G~do not percolate, we further determine by means of isomorphism theory the exact law of the capacity of compact clusters at any height. Specifically, we derive this law from an extension of Sznitman’s refinement of Lupu’s recent isomorphism theorem relating the free field and random interlacements, proved along the way, and which holds under the sole assumption that sign clusters on$$\widetilde{{\mathcal {G}}}$$G~are bounded. Finally, we show that the law of the cluster capacity functionals obtained in this way actually characterizes the isomorphism theorem, i.e. the two are equivalent.
Distinct prognostic value of different portal hypertension-associated features in patients with primary biliary cholangitis
Authors: Burghart Lukas , Halilbasic Emina , Schwabl Philipp , Simbrunner Benedikt , Stättermayer Albert Friedrich , Petrenko Oleksandr , Scheiner Bernhard , Bauer David , Pinter Matthias , Boztug Kaan , Mandorfer Mattias , Trauner Michael , Reiberger Thomas 
Published: December 2021

AbstractBackgroundPrimary biliary cholangitis (PBC) may progress to cirrhosis and clinically significant portal hypertension (CSPH). This study assesses different features of CSPH and their distinct prognostic impact regarding decompensation and survival in patients with PBC.MethodsPatients with PBC were identified during a database query of our digital patient reporting system.ResultsA total of 333 PBC patients (mean age 54.3 years, 86.8% females, median follow-up 5.8 years) were retrospectively assessed and 127 (38.1%) showed features of CSPH: 63 (18.9%) developed varices, 98 (29.4%) splenomegaly, 62 (18.6%) ascites and 20 (15.7%) experienced acute variceal bleeding. Splenomegaly, portosystemic collaterals and esophageal varices were associated with an increased 5-year (5Y) risk of decompensation (15.0%, 17.8% and 20.9%, respectively). Patients without advanced chronic liver disease (ACLD) had a similar 5Y-transplant free survival (TFS) (96.6%) compared to patients with compensated ACLD (cACLD) but without CSPH (96.9%). On the contrary, PBC patients with cACLD and CSPH (57.4%) or decompensated ACLD (dACLD) (36.4%) had significantly decreased 5Y survival rates. The combination of LSM < 15 kPa and platelets ≥ 150G/L indicated a negligible risk for decompensation (5Y 0.0%) and for mortality (5Y 0.0%). Overall, 44 (13.2%) patients died, with 18 (40.9%) deaths attributed to CSPH-related complications.ConclusionIn PBC, features of CSPH may occur early and indicate an increased risk for subsequent decompensation and mortality. Hence, regular screening and on-time treatment for CSPH is crucial. Combining LSM and platelets serves as a valuable preliminary assessment, as LSM < 15 kPa and platelets ≥ 150G/L indicate an excellent long-term outcome.
Socio-legal systems and implementation of the Nash solution in Debreu–Hurwicz equilibrium
Authors: Haake Claus-Jochen , Trockel Walter 
Published: December 2021

AbstractIn this article we combine Debreu’s (Proc Natl Acad Sci 38(10):886–893, 1952) social system with Hurwicz’s (Econ Design 1(1):1–14, 1994; Am Econ Rev 98(3):577–585, 2008) ideas of embedding a “desired” game form into a “natural” game form that includes all feasible behavior, even if it is “illegal” according to the desired form. For the resulting socio-legal system we extend Debreu’s concepts of a social system and its social equilibria to a socio-legal system with its Debreu–Hurwicz equilibria. We build on a more general version of social equilibrium due to Shafer and Sonnenschein (J Math Econ 2(3):345–348, 1975) that also generalizes the dc-mechanism of Koray and Yildiz (J Econ Theory 176:479–502, 2018) which relates implementation via mechanisms with implementation via rights structures as introduced by Sertel (Designing rights: invisible hand theorems, covering and membership. Tech. rep. Mimeo, Bogazici University, 2001). In the second part we apply and illustrate these new concepts via an application in the narrow welfarist framework of two person cooperative bargaining. There we provide in a socio-legal system based on Nash’s demand game an implementation of the Nash bargaining solution in Debreu–Hurwicz equilibrium.
Policy Lessons From Medical Responses to the COVID-19 Crisis
Authors: Dosi Giovanni 
Published: December 2021

AbstractThis article discusses the medical/therapeutical responses to the COVID-19 pandemic and their political economy context. First, the very quick development of several vaccines highlights the richness of the basic knowledge waiting for therapeutical exploitation. Such knowledge has largely originated in public or non-profit institutions. Second, symmetrically, there is longer-term evidence that the private sector (essentially big pharma) has decreased its investment in basic research in general and has long been uninterested in vaccines in particular. Only when flooded with an enormous amount of public money did it become eager to undertake applied research, production scale-up and testing. Third, the political economy of the underlying public-private relationship reveals a profound dysfunctionality with the public being unable to determine the rates and direction of innovation, but at the same time confined to the role of payer of first and last resort, with dire consequences for both advanced, and more so developing countries. Fourth, on normative grounds, measures like ad hoc patent waivers are certainly welcome, but this will not address the fundamental challenge, involving a deep reform of the intellectual property rights regimes and their international protection.
Modern Monetary Theory: A Wrong Compass for Decision-Making
Authors: Drumetz Françoise , Pfister Christian 
Published: December 2021

AbstractIn the last few years, the so-called Modern Monetary Theory (MMT) has been gaining prominence in the media and the public. This article presents the MMT approach to money and monetary policy, and discusses its recommendations regarding fiscal policy and aggregate demand management, the structural policies it advocates as well as the international aspects of MMT. Overall, it appears that MMT is based on an outdated state of economic science and that its claims regarding economic policies are much exaggerated: The meaning of MMT is more that of a political manifesto than of a genuine economic theory.
Association Between Maternal HIV Stigma Among South Indian Mothers Living with HIV and the CD4 Count of Children Living with HIV
Authors: PhamDo Valerie , Nyamathi Adeline M. , Ekstrand Maria L. , Sinha Sanjeev , Yadav Kartik , Shin Sanghyuk S. 
Published: December 2021

AbstractHIV stigma takes a multidimensional toll on a mother’s ability to care for herself and subsequently may impact her ability to care for her child, particularly when mother and child are seroconcordant. A cross-sectional analysis was conducted to examine the association between maternal HIV stigma and child CD4 count in rural India. We assessed 108 mother–child dyads and found that a one-unit increase in community stigma fear decreased child CD4 count by 352 cells (95% CI = − 603, − 102), highlighting the need to develop a better understanding of the consequences of HIV-related stigma on the compounded burden of care in households where mother and child both live with HIV.
Influence of Material Deprivation on Clinical Outcomes Among People Living with HIV in High-Income Countries: A Systematic Review and Meta-analysis
Authors: Papageorgiou Vasiliki , Davies Bethan , Cooper Emily , Singer Ariana , Ward Helen 
Published: December 2021

AbstractDespite developments in HIV treatment and care, disparities persist with some not fully benefiting from improvements in the HIV care continuum. We conducted a systematic review to explore associations between social determinants and HIV treatment outcomes (viral suppression and treatment adherence) in high-income countries. A random effects meta-analysis was performed where there were consistent measurements of exposures. We identified 83 observational studies eligible for inclusion. Social determinants linked to material deprivation were identified as education, employment, food security, housing, income, poverty/deprivation, socioeconomic status/position, and social class; however, their measurement and definition varied across studies. Our review suggests a social gradient of health persists in the HIV care continuum; people living with HIV who reported material deprivation were less likely to be virologically suppressed or adherent to antiretrovirals. Future research should use an ecosocial approach to explore these interactions across the lifecourse to help propose a causal pathway.
Bridging theory and practice in ecosystem services mapping: a systematic review
Authors: Bitoun Rachel E. , Trégarot Ewan , Devillers Rodolphe 
Published: December 2021

AbstractThe mapping and assessment of Ecosystem Services (ES) aims at better connecting environmental conservation, economic development, and human well-being. However, 60 years after the development of the ES concept, a persistent gap remains between the production of scientific knowledge on ES and its use in support of policy and management. Here, we report on a systematic review of the scientific literature that helps better understand key challenges and offers potential solutions to bridge this gap. The review considered four criteria: (1) how stakeholders participate to studies; (2) how usable ES maps are for decision-making; (3) what policy recommendations were made; and (4) what research recommendations were made. The analysis of 135 papers published between 2008 and 2020 revealed diverse technical and conceptual challenges that could prevent the effective use of ES concepts and methods outside the academic realm. The main challenges identified in the literature were the uncertainty levels of ES mapping outputs, issues of spatial scales, the understanding of ES interactions, and the need for temporal analysis. Many policies rely on mapped outcomes, creating a window of opportunity for the uptake of ES mapping into policy-making. However, it remains key to involve stakeholders early in the co-design of ES studies and to better understand their preferences and motivation to adopt ES mapping in their practices. The study shows that higher levels of learnability of ES mapping practices, further popularization to foster public awareness, and increased capacity building would facilitate the ES concept uptake into decision and policy-making.
Rich diversity in cultivated Finnish potato onions (Allium cepa var. aggregatum G. Don)
Authors: Suojala-Ahlfors Terhi , Heinonen Maarit , Tanhuanpää Pirjo , Antonius Kristiina 
Published: December 2021

AbstractPotato onion (Allium cepa var. aggregatum G. Don) remained the most widely grown onion type in Finland up to the 1950’s, after which the more productive cultivars of common onion replaced this vegetatively propagated onion type. The Finnish accessions have been maintained in two national plant genetic resources (PGR) collections since 1990’s but new samples have been obtained still later. In this research, we analysed the genetic diversity of potato onions and shallots, grown in home gardens and in PGR collection, and compared the uniformity of the two PGR collections. One hundred ten onion samples were analysed using eight microsatellite loci, which amplified 83 alleles in total. There was a large number of genetically different samples, forming four major groups in the dendrogram. The results show that there is still a lot of genetic diversity among the Finnish potato onions, even though they are propagated vegetatively. The rich diversity in the samples obtained from citizens reflects a valuable source of genetic resources maintained by home gardeners. The national collection has been updated on the basis of the results. To ensure the preservation of the rich onion heritage, efforts are needed to increase the availability of potato onion to home gardeners and commercial growers.
Comparison of the efficiency of the most effective heterogeneous nucleating agents for Poly(lactic acid)
Authors: Ageyeva Tatyana , Kovács József Gábor , Tábi Tamás 
Published: December 2021

AbstractWe selected the thirteen most effective nucleating agents for Poly(lactic acid) (PLA) from the literature, and synthesized and compounded them with two different PLA grades: 3001D (1.4% D-lactide content) and 3100HP (0.5% D-lactide content, considered PLLA). We determined the crystallinity and crystallization of PLA with different nucleating agents in identical conditions (same nucleating agent content, same cooling rate) with the help of differential scanning calorimetry. We compared the efficiency of each nucleating agent and found that for both PLA grades, Zinc PhenylPhosphonate was the most effective. However, even when nucleated PLA was injection molded into a cold mold (25 °C), it still could not fully crystallize during cooling and the heat deflection temperature did not increase significantly. The maximum achieved crystallinity, in this case, was between 32.4 and 35.7%. On the contrary, when a 90 °C “hot mold” and in-mold crystallization together were applied, the specimens achieved full crystallization during the injection molding cycle (crystallinity was between 44.5 and 50.0%), and the heat deflection temperature increased to an average of 88.8 °C. We also examined the mechanical properties of the nucleated PLA and found that the usage of nucleating agents together with a hot mold improved tensile strength, tensile modulus, and Charpy impact strength but decreased elongation at break.