bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health Behaviors and Wellbeing among those “LIVING” with Metastatic Cancer in the Deep South
Authors: Bail Jennifer R , Bail Sumanth V , Cagle Jessica , Tiesi Koriann , Caffey Jayla , Bakitas Marie , Demark-Wahnefried Wendy 
Published: March 2021

Abstract
Background: Approximately 5 million Americans are living with metastatic cancer. Metastatic cancer survivors (MCS) are at risk for poor health behaviors, which may negatively influence wellbeing.Methods: Using a modified Dillman’s method, 542 MCS were mailed a survey querying physical and mental health (PROMIS® measures), health behaviors, and supportive care interest. Returned surveys were double-key entered into REDCap®. Data were analyzed using SPSS.Results: Two hundred and seventy-seven surveys were returned (51% response). Respondents (51% female; 88% Caucasian; 12% African-American; Mage=65 years; Msurvivorship=38 months; 23% female cancers, 23% melanoma, 21% gastrointestinal, 15% genitourinary, 12% pulmonary, and 6% other) reported low daily fruit and vegetable (F&V) intake (M=4.1) and weekly minutes of moderate-to-vigorous physical activity (PA) (M=41.9), with 66% of respondents having overweight or obesity. While mean scores for physical (M=43.6) and mental (M=47.7) health were considered “good,” scores in the “fair” to “poor” ranges were observed (40% physical; 23% mental). MCS meeting PA (≥150 min per week) and dietary (≥5 daily servings of F&V) guidelines reported better physical (p=.003; p=.056) and mental (p=.033, p=.549) health respectively, compared to MCS who were not. While current supportive care use was low (12%), future interest was high (57%), with greatest interest for nutrition (46%), MCS support group (38%), and gardening (31%).Conclusions: Our findings suggest that engaging in regular PA and consuming more F&Vs may enhance physical and mental health among MCS. Future research may explore supportive care approaches with high interest, such as gardening, to aid MCS in improving key health behaviors.
Assessing phytotoxicity and accumulation of trace elements to Lactuca sativa of a contaminated shooting range soil
Authors: Cesynaite Jurate , Praspaliauskas Marius , Sujetoviene Gintare 
Published: March 2021

Abstract
Shooting range soil contamination with heavy metals is a common problem around the world. Usually, lead is the primary contaminant in the shooting ranges. Extreme concentrations of trace elements create a toxic living environment for various plants. The purpose of this study was to evaluate the effect on lettuce (Lactuca sativa L.) grown in contaminated shooting range soil. The results showed that physiological parameters root elongation, shoot length and fresh biomass per plant were negatively affected, especially in the most contaminated site in the shooting range. At the most contaminated shooting range site shoots accumulated higher concentrations of Ni and Zn, roots – Cu, Ni, and Zn. The roots of plants grown in the most contaminated soil accumulated significantly higher concentrations of Cu, Ni, and Sb than the reference and accumulation of Cu, Fe, Mn, Ni, Sb and Zn in the roots of the plants grown in the most contaminated site was higher compared to shoots. Bioaccumulation factor of Cu and Ni in plants from the most contaminated site was significantly higher than the reference. Metals absorbed by L. sativa were accumulated in root and lower metal translocation in shoots was determined, except for Mn.
Effect of two insect diets on the intestinal commensal microbiome of healthy Salmo trutta vr. trutta
Authors: Józefiak Agata , Nogales-Mérida Silvia , Rawski Mateusz , Mikołajczak Zuzanna , Kierończyk Bartosz , Włodarek Jan , Mazurkiewicz Jan 
Published: March 2021

Abstract
Background The balance of the intestinal commensal microbiome of fish and other animals plays an important role in the physiological processes of healthy animals, contributes to the defense against pathogens, stimulates the immune system and facilitates nutrient metabolism. In the last decade, the use of insects in fish nutrition has been increasing exponentially, although little is known regarding the effects of insect meals on the fish gastrointestinal tract. The aim of this study was to evaluate the effect of two insect diets containing mealworm (MW) and superworm (SW) on the microbiome of the digesta of sea trout fingerlings and the relative abundances of different taxa among communities under controlled conditions.Results The insect meals produced a similar weight gain and survival rate to sea trout fed fishmeal. The most abundant bacterial phylum in all the treatment groups was Firmicutes followed by Proteobacteria and Actinobacteria, and significant differences in the amount of Cyanobacteria were observed in the SW group. Conclusions The insect meals did not produce differences in the three most abundant phyla in the sea trout digesta. However, the effect of each type of meal on the lower taxonomic levels was evident, particularly in the case of the superworm meal. These microbiome differences indicated that mealworm meal was more related to fishmeal than superworm meal. Our results highlight the potential effects of insect meals, such as mealworm and superworm meals, on the microbiota of sea trout.
Dynamic Thiol Disulphide Homeostasis in Patients with Surfer’s Eye: A Case-Control Study
Authors: Akcam Hanife Tuba , Erel Ozcan 
Published: March 2021

Abstract
Purpose
The role of oxidative stress in the pathogenesis of pterygium is still unclear. However, abnormal thiol disulfide homeostasis levels are involved in the pathogenesis of various systemic or ocular diseases. We aim to analyze dynamic thiol disulphide homeostasis in patients suffering from conjunctival pterygium using a contemporary technique.
Methods
Thirty-eight subjects suffering from pterygium and 35 age-gender matched healthy volunteers were recruited for study. For each case, total thiol, disulfide and native thiol levels in blood were obtained. Additionally, ratio of disulfide over total thiol, native thiol over total thiol and disulfide over native thiol were computed.
Results
The level of median native thiol was lower in pterygium group (318.2 µmol /L vs 333.4 µmol /L) and median disulfide was slightly higher in pterygium group (24.3 µmol /L vs 22.8 µmol /L) compared to control group. Both disulfide over total thiol and disulfide over native thiol ratios were higher in pterygium group, ratio of native thiol over total thiol was found to be higher in control group. Nevertheless, none of those differences were statistically significant at 95% confidence level. Notably, correlation test pointed to a negative correlation both between pterygium grade and native thiol and between total thiol and pterygium grade in pterygium group (P = 0.03 and 0.02 respectively).
Conclusion
A negative correlation hinting that slightly weakened dynamic thiol disulphide homeostasis in subjects with pterygium, a local ocular disease. Further studies with larger sample sizes may shed light on this potential relationship and justify systemic antioxidant therapies in these cases.
Evaluation of GIS based Ranking and AHP methods in selecting the most suitable site: A case study in Kayseri, Turkey
Authors: Günen Mehmet Akif 
Published: March 2021

Abstract
Demand for renewable energy sources is increasing since traditional energy sources (i.e., coal, oil, and natural gas) have limited reserves and cause high greenhouse gas emission. Suitable site selection for new generation renewable resources is vital in large-scale projects. In this paper, suitable sites for solar photovoltaic (PV) power plants were selected for a Kayseri, Turkey case. Geographic information systems and multi criteria decision-making (MCDM) methods were integrated to exploit and construct the best location for solar PV power plants. In this context, three main, twelve sub-criteria, and their indicators were determined by considering expert opinion and previous studies. The rank based (i.e., rank sum, rank reciprocal weights, and rank order centroid weights) and analytical hierarchical process (AHP) methods were used to determine the weights of the criteria. The suitability maps created according to the calculated weights were divided into 5 levels (i.e., excellent, good, fair, low, poor site). To compare the success of MCDM methods, 33 existing installed PV power plants were randomly selected and used for validation. It was determined that the rank reciprocal method was the most successful in selection of the most suitable site. Four MCDM methods determined that the Sarız, Tomarza, and Incesu districts of Kayseri were the most suitable sites.
Recovery of Respiratory Muscle, Physical Functions, and Dyspnea After Lobectomy for Lung Cancer
Authors: Ichikawa Tsuyoshi , Yokoba Masanori , Horimizu Yu , Yamaguchi Saki , Kawakami Akiko , Oikawa Satoru , Takeichi Haruka , Katagiri Masato , Toyokura Minoru 
Published: March 2021

Abstract
Purpose: To characterize respiratory muscle strength, physical functions, and dyspnea in patients receiving pulmonary rehabilitation following lobectomy for non-small cell lung cancer.Methods: This retrospective study included non-small cell lung cancer patients who underwent lobectomy via video-assisted thoracoscopic surgery or posterolateral thoracotomy and pulmonary rehabilitation between September 2013 and March 2018. Maximum mouth inspiratory and expiratory pressures, 6-minute walking distance, quadriceps force, and modified Medical Research Council dyspnea scale score were evaluated before surgery, at discharge, and at post-lobectomy months 1 and 3.Results: Data from 41 eligible patients were analyzed. At discharge, maximum mouth inspiratory and expiratory pressures, 6-minute walking distance, and modified Medical Research Council dyspnea scale score were lower than pre-operative values, but quadriceps force was unchanged. The maximum mouth inspiratory pressure and 6-minute walking distance returned to pre-operative values at post-lobectomy month 1, and maximum expiratory pressure and modified Medical Research Council dyspnea scale score improved at month 3. During sub-analysis, maximum mouth inspiratory pressure and modified Medical Research Council dyspnea scale score after video-assisted thoracoscopic surgery (n = 24) improved to pre-operative levels at post-lobectomy month 1, whereas patients in the posterolateral thoracotomy group (n = 17), it improved at 3 months.Conclusions: After lobectomy for non-small cell lung cancer, patients undergoing pulmonary rehabilitation had their respiratory muscle strength, physical functions, and dyspnea improve to pre-operative levels at post-lobectomy month 3. Moreover, video-assisted thoracoscopic surgery may be more beneficial than posterolateral thoracotomy in the early post-operative recovery of inspiratory muscle strength and dyspnea.
A new nonlinear mathematical model for forecasting the waves of the COVID-19 epidemic
Authors: Yaghoby Reza 
Published: March 2021

Abstract
Social distance and Hospitals' capacity are two very important factors in the COVID-19 pandemic, which usually change over time. Nevertheless, studies on forecasting this pandemic have not approximately considered these changes in their models. In this study, we accordingly provided a new nonlinear diffusion model by considering these changes for forecasting the COVID-19 outbreak in Iran. This new model generally indicated that it can well follow and predict the trends of the new cases, new recoveries and daily deaths relevant to Iran’s COVID-19 epidemic. In this model, some outcomes also indicated that this model can detect some-things about the management style of the COVID-19 epidemic in Iran. Therefore, since this model could follow three waves of the COVID-19 outbreak in Iran, it can be used in mitigation strategies for the better management of the COVID-19 epidemic in Iran and even other world countries.
Association between the modified Nutrition Risk in Critically Ill (mNUTRIC) score and clinical outcomes in the intensive care unit: A secondary analysis of a large prospective observational study
Authors: Wang Na , Wang Mei-Ping , Jiang Li , Du Bin , Zhu Bo , Xi Xiu-Ming 
Published: March 2021

Abstract
Background: Malnutrition in intensive care unit (ICU) patients is associated with adverse clinical outcomes. The nutrition risk in the critically ill score (NUTRIC) was proposed as an appropriate nutritional assessment tool in critically ill patients. This score uses interleukin-6 (IL-6), a biomarker that is not always available. This prospective observational study was conducted to identify the nutritional risk in ICU patients using the modified NUTRIC (mNUTRIC) score (which does not include IL-6) and to explore the relationship between 28-day mortality and high mNUTRIC scores.Methods: The data were extracted from The Beijing Acute Kidney Injury Trial (BAKIT). This trial was a prospective, observational, multi-centre study conducted in 30 ICUs at 28 tertiary hospitals in Beijing, China, from March 1 to August 31, 2012. In total, 9049 patients were admitted consecutively, and 3107 patients with complete clinical data were included in this study. The predictive capacity of the mNUTRIC score was studied by receiver operating characteristic (ROC) curve analysis. The significance level was set at 5%.Results: Among the 3107 patients, the 28-day mortality rate was 17.4% (540 patients died). High nutritional risk patients were older (P<0.001), with higher illness severity scores than low nutritional risk patients. Multivariate analysis revealed that the mNUTRIC score was an independent risk factor for 28-day mortality and mortality increased with increasing scores (p = 0.000). The calculated area under curve (AUC) for the mNUTRIC score was 0.763 (CI 0.740 - 0.786).Conclusions: Nearly 28.2% of patients admitted to the ICU were at risk of malnutrition, and a high mNUTRIC score was associated with increased ICU length of stay and higher mortality.Trial Registration: This study was registered at www.chictr.org.cn (registration number Chi CTR-ONC-11001875). Registered on 14 December 2011.Key words:The modified nutrition risk in critically ill score, Intensive care unit, Mortality
Biofuels from wastes in the Marmara Region, Turkey: Potentials and constraints
Authors: Ocak Semra , Acar Sevil 
Published: March 2021

Abstract
Turkey as an energy importing country, is heavily dependent on fossil fuels, which causes an increase in environmental problems and raises concerns on energy security. However, biowastes offer a significant potential, especially in the Marmara Region of the country. In this study, the waste potential of the region for energy production is analyzed. Within this context, agricultural and livestock wastes are examined in terms of their amounts, theoretical energy potentials and costs to generate electricity. To evaluate economic costs, collection and feedstock costs for animal and agricultural wastes are handled in three different scenarios based on FAO’s assessment. Given the results for wastes and energy potentials, it has been deduced that biowastes can theoretically meet more than half of the electricity consumption of the region. The results of the cost analysis demonstrate that both direct combustion of agricultural wastes and conversion of animal wastes to biogas in CHP plants to produce electricity are economical according to several scenario options considering the LCOE and feed-in-tariff values.
Comparative assessment of LDL-C and VLDL-C estimation in Familial Combined Hyperlipidemia using Sampson’s, Martin’s and Friedewald’s equations
Authors: Vargas-Vázquez Arsenio , Bello-Chavolla Omar Yaxmehen , Antonio-Villa Neftali Eduardo , Mehta Roopa , Aguilar-Salinas Carlos A. , Cruz-Bautista Ivette 
Published: March 2021

Abstract
Background: Sampson et al developed a novel method to estimate very low-density lipoprotein cholesterol (VLDL-C) and low-density lipoprotein cholesterol (LDL-C) in the setting of hypertriglyceridemia. Familial Combined Hyperlipidemia (FCHL) is a common primary dyslipidemia in which lipoprotein composition interferes with LDL-C estimation. This study aimed to evaluate performance of LDL-C using this new method (LDL-S) compared with LDL-C estimated by Friedewald’s and Martin equation (LDL-F, LDL-M) in FCHL.Methods: Data were collected from 340 subjects with confirmed FCHL. Concordance for VLDL-C measured by ultracentrifugation and LDL-C estimated using these measures compared to Sampson’s, Martin’s and Friedewald’s equations was performed using correlation coefficients, root mean squared error (RMSE) and bias. We also assessed concordance of misclassified metrics according to LDL-C (<70 and <100mg/dL) and ApoB (<80 and <65mg/dL) thresholds.Results: Sampson’s equation was more accurate (RMSE 11.21 mg/dL; R2=0.88) compared to Martin’s (RMSE 13.15 mg/dL; R2=0.875) and the Friedewald equation (RMSE 13.7 mg/dL; R2= 0.869). When assessing performance according to LDL-C, Sampson’s had highest correlation and lowest RMSE compared to other equations (RMSE 19.99 mg/dL; R2=0.840). Comparing performance strength across triglyceride levels, Sampson’s showed consistently improved correlations compared to Martin’s and Friedewald’s formulas for increasing triglycerides and for the FCHL phenotype of mixed dyslipidemia. Sampson’s also had improved concordance with treatment goals.Conclusions: In FCHL, VLDL-C and LDL-C estimation using Sampson’s formula showed higher concordance with lipid targets assessed using VLDL-C obtained by ultracentrifugation compared with Friedewald’s and Martin’s equations. Implementation of Sampson’s formula could improve treatment monitoring in FCHL.
Microbiome-Gut-Brain-Axis communication influences metabolic switch in the mosquito Anopheles culicifacies
Authors: De Tanwee Das , Sharma Punita , Tevatiya Sanjay , Chauhan Charu , Kumari Seena , Singla Deepak , Srivas Vartika , Rani Jyoti , Hasija Yasha , Pandey Kailash , Mayur Kajla , Dixit Rajnikant 
Published: March 2021

Abstract
Background: Periodic ingestion of a protein-rich blood meal by adult female mosquitoes causes a drastic metabolic change in their innate physiological status, which is referred to as ‘metabolic switch. Although the down-regulation of olfactory factors is key to restrain host-attraction, how the gut ‘metabolic switch’ modulates brain functions, and resilience physiological homeostasis remains unexplored. Methods: To uncover a possible correlation of gut metabolic switching and brain function, we carried out a comparative RNAseq analysis of naïve and blood-fed mosquito’s brain. Spatio-temporal expression of neuro-signaling and neuro-modulatory genes was monitored through Real-Time PCR. To establish a proof-of-concept, we followed LC/MS-based absolute quantification of different neurotransmitters (NT) and compared their levels in the brain as well as in the gut of the mosquitoes. To correlate how microbiome influences gut-brain-axis communication, we performed a comparative gut metagenomic analysis. Results: Our findings demonstrate that the protein-rich diet induces the expression of brain transcripts related to mitochondrial function and energy metabolism, possibly to cause a shift of the brain’s engagement to manage organismal homeostasis. A dynamic expression pattern of neuro-signaling and neuro-modulatory genes in both gut and brain, presumably a key to establish an active brain-distant organ communication. Disruption of this comunication through decapitation, does not affect the modulation of the neuro-modulator receptor genes in the gut. In parallel, an unusual and paramount shift in the level of the Neurotransmitters (NTs), from the brain to the gut after blood feeding, further supports the idea of the gut’s ability to serve as a ‘second brain’. Finally, a comparative metagenomics evaluation of gut microbiome population dynamics, highlighted that blood-feeding not only suppresses Enterobacteriaceae family member by 50%, but favors rapid proliferation of Pseudomonadales to 46% of the total community. Notable obesrvation of a rapid proliferation of Pseudomonas bacterial sp. in the gut correlates a possible cause for the suppression of appetite after blood-feeding. Additionally, an altered NTs dynamics of naïve and aseptic mosquitoes provide the initial evidence that gut-endosymbionts are key modulators for the synthesis of major neuroactive molecules. Conclusion: Our data establish a new conceptual understanding of microbiome-gut-brain-axis communication in mosquitoes.
Wormhole Attack Detection System for IoT Network: A Hybrid Approach
Authors: Bhosale Snehal Ajit , Sonavane S. S. 
Published: March 2021

Abstract
Many errors in data communication cause security attacks in Internet of Things (IoT). Routing errors which are prominent errors in IoT, degrade the quality of data communication. Many attacks like sinkhole attack, blackhole attack, selective forwarding attack and wormhole attack enter the network through network layer of the IoT. This paper has an emphasis on the wormhole attack detection because it is one of the most uncompromising attacks at the network layer of IoT protocol stack. The wormhole attack inserts wrong routes information in the network; it also alters the network information by causing failure of the location-dependent protocols thus defeating the purpose of routing algorithms. The wormhole attack is activated in the network by forming a tunnel between two long-distance nodes. These nodes create an illusion that they are directly connected and nearer to each other. They attract legitimate nodes to transmit data through them by advertising less hop-count. Most of the time, due to the presence of attack, packets take the long route and reduce their strength. This paper covers the design and implementation of an innovative intrusion detection system for the IoT that detects the wormhole attack and the attacker nodes. The presence of the wormhole attack is identified using location information of any node and its neighbor with the help of Received Signal Strength Indicator (RSSI) values and hop-count. The proposed system is energy efficient and hence it is beneficial for a resource-constrained environment of IoT. It also provides precise true-positive and false-positive detection rate.
Spherical Dielectric Resonator Antenna for 5G Application
Authors: kumar Ashok , Yaduvanshi Rajveer Singh 
Published: March 2021

Abstract
In this article Spherical DRA has been formulated , simulated and proto type developed. The detailed theoretical analysis along with simulations and measured results at 5.8 GHz have been presented in this article. The SDRA at 5.8 GHz covering 5G frewuenci band. The proposed design antenna provides the gain of 7.3 dB and return loss -25 dB. The measured results are in good match with simulated result. The proposed SDRA are good for 5G wireless networks, as well as other sub-6 band in wireless communication systems.