bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Novel Approach to First-Rib Resection in Neurogenic Thoracic Outlet Syndrome
Authors: Li Yueying , Liu Yanxi , Zhang Zhan , Gao Xuehai , Cui Shusen 
Published: November 2021

Objectives: The treatment for neurogenic thoracic outlet syndrome (NTOS) conventionally involves first-rib resection (FRR) surgery, which is quite challenging to perform, especially for novices, and is often associated with postoperative complications. Herein, we report a new segmental resection approach through piezo surgery that involves using a bone cutter, which can uniquely provide a soft tissue protective effect.Methods: This retrospective study involved the examination of 26 NTOS patients who underwent piezo surgery and another group of 30 patients who underwent FRR using the conventional technique. In the patient group that underwent piezo surgery, the rib was first resected into two pieces using a piezoelectric device and subsequently removed. In the patient group that underwent conventional surgery, the first rib was removed as one piece using a rib cutter and rongeurs.Results: The piezo surgery group had significantly shorter operative time (96.85 ± 14.66 vs. 143.33 ± 25.64 min, P &lt; 0.001) and FRR duration (8.73 ± 2.11 vs. 22.23 ± 6.27 min, P &lt; 0.001) than the conventional group. The posterior stump length of the residual rib was shorter in the piezo surgery group than in the conventional group (0.54 ± 0.19 vs. 0.65 ± 0.15 cm, P &lt; 0.05). There were no significant differences in postoperative complications and scores of the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire, the Cervical Brachial Symptom Questionnaire (CBSQ), and the visual analog scale (VAS). Even the TOS index (NTOS Index = [DASH + (0.83 × CBSQ) + (10 × VAS)]/3) and patient self-assessments of both the groups showed no significant differences. Univariate analyses indicated that the type of treatment affected operative time.Conclusion: Our results suggest that piezo surgery is safe, effective, and simple for segmental FRR in NTOS patients. Piezo surgery provides a more thorough FRR without damaging adjacent soft tissues in a relatively short duration and achieves similar functional recovery as conventional techniques. Therefore, piezo surgery can be a promising alternative for FRR during the surgical treatment of NTOS.
Antimicrobial Resistance and Genomic Characterization of Six New Sequence Types in Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates from Pakistan
Authors: Irum Sidra , Naz Kanwal , Ullah Nimat , Mustafa Zeeshan , Ali Amjad , Arslan Muhammad , Khalid Kashaf , Andleeb Saadia 
Published: November 2021

Pseudomonas aeruginosa (P. aeruginosa) is a major bacterial pathogen associated with a variety of infections with high mortality rates. Most of the clinical P. aeruginosa isolates belong to a limited number of genetic subgroups characterized by multiple housekeeping genes’ sequences (usually 5–7) through the Multi-Locus Sequence Typing (MLST) scheme. The emergence and dissemination of novel multidrug-resistant (MDR) sequence types (ST) in P. aeruginosa pose serious clinical concerns. We performed whole-genome sequencing on a cohort (n = 160) of MDR P. aeruginosa isolates collected from a tertiary care hospital lab in Pakistan and found six isolates belonging to six unique MLST allelic profiles. The genomes were submitted to the PubMLST database and new ST numbers (ST3493, ST3494, ST3472, ST3489, ST3491, and ST3492) were assigned to the respective allele combinations. MLST and core-genome-based phylogenetic analysis confirmed the divergence of these isolates and positioned them in separate branches. Analysis of the resistome of the new STs isolates revealed the presence of genes blaOXA-50, blaPAO, blaPDC, blaVIM-2, aph(3′)-IIb, aac(6′)-II, aac(3)-Id, fosA, catB7, dfrB2, crpP, merP and a number of missense and frame-shift mutations in chromosomal genes conferring resistance to various antipseudomonal antibiotics. The exoS, exoT, pvdE, rhlI, rhlR, lasA, lasB, lasI, and lasR genes were the most prevalent virulence-related genes among the new ST isolates. The different genotypic features revealed the adaptation of these new clones to a variety of infections by various mutations in genes affecting antimicrobial resistance, quorum sensing and biofilm formation. Close monitoring of these antibiotic-resistant pathogens and surveillance mechanisms needs to be adopted to reduce their spread to the healthcare facilities of Pakistan. We believe that these strains can be used as reference strains for future comparative analysis of isolates belonging to the same STs.
Clusters of Survivors of COVID-19 Associated Acute Respiratory Failure According to Response to Exercise
Authors: Vitacca Michele , Paneroni Mara , Malovini Alberto , Carlucci Annalisa , Binda Chiara , Sanci Vincenzo , Ambrosino Nicolino 
Published: November 2021

COVID-19 survivors are associated with acute respiratory failure (ARF) and show a high prevalence of impairment in physical performance. The present studied aimed to assess whether we may cluster these individuals according to an exercise test. The presented study is a retrospective analysis of 154 survivors who were admitted to two hospitals of Istituti Clinici Scientifici Maugeri network, Italy. Clinical characteristics, walked distance, heart rate (HR), pulse oximetry (SpO2), dyspnoea, and leg fatigue (Borg scale: Borg-D and Borg-F, respectively) while performing the six-minute walking test (6MWT) were entered into unsupervised clustering analysis. Multivariate linear regression identified variables that were informative for the set of variables used for cluster definition. Cluster 1 (C1: 86.4% of participants) and Cluster 2 (C2: 13.6%) were identified. Compared to C1, the individuals in C2 were significantly older, showed significantly higher increase in fatigue and in dyspnoea, greater reduction in SpO2, and a lower HRpeak during the test. The need of walking aids, time from admission to acute care hospitals, age, body mass index, endotracheal intubation, baseline HR and baseline Borg-D, and exercise-induced SpO2 change were significantly associated with the variables that were used for cluster definition. Different characteristics and physiological parameters during the 6MWT characterise survivors of COVID-19-associated ARF. These results may help in the management of the long-term effects of the disease.
Relationship between Sea Surface Drag Coefficient and Wave State
Authors: Shi Jian , Feng Zhihao , Sun Yuan , Zhang Xueyan , Zhang Wenjing , Yu Yi 
Published: November 2021

The sea surface drag coefficient plays an important role in momentum transmission between the atmosphere and the ocean, which is affected by ocean waves. The total air–sea momentum flux consists of effective momentum flux and sea spray momentum flux. Sea spray momentum flux involves sea surface drag, which is largely affected by the ocean wave state. Under strong winds, the sea surface drag coefficient (CD) does not increase linearly with the increasing wind speed, namely, the increase of CD is inhibited by strong winds. In this study, a sea surface drag coefficient is constructed that can be applied to the calculation of the air–sea momentum flux under high wind speed. The sea surface drag coefficient also considers the influence of wave state and sea spray droplets generated by wave breaking. Specially, the wave-dependent sea spray generation function is employed to calculate sea spray momentum flux. This facilitates the analysis not only on the sensitivity of the sea spray momentum flux to wave age, but also on the effect of wave state on the effective CD (CD, eff) under strong winds. Our results indicate that wave age plays an important role in determining CD. When the wave age is >0.4, CD decreases with the wave age. However, when the wave age is ≤0.4, CD increases with the wave age at low and moderate wind speeds but tends to decrease with the wave age at high wind speeds.
Expression Patterns of miR398, miR167, and miR159 in the Interaction between Bread Wheat (Triticum aestivum L.) and Pathogenic Fusarium culmorum and Beneficial Trichoderma Fungi
Authors: Salamon Sylwia , Żok Julia , Gromadzka Karolina , Błaszczyk Lidia 
Published: November 2021

Bread wheat (Triticum aestivum L.) is an agronomically significant cereal cultivated worldwide. Wheat breeding is limited by numerous abiotic and biotic stresses. One of the most deleterious factors is biotic stress provoked by the Fusarium culmorum fungus. This pathogen is a causative agent of Fusarium root rot and Fusarium head blight. Beneficial fungi Trichoderma atroviride and T. cremeum are strong antagonists of mycotoxigenic Fusarium spp. These fungi promote plant growth and enhance their tolerance of negative environmental conditions. The aim of the study was to determine and compare the spatial (in above- and underground organs) and temporal (early: 6 and 22 hpi; and late: 5 and 7 dpi reactions) expression profiles of three mature miRNAs (miR398, miR167, and miR159) in wheat plants inoculated with two strains of F. culmorum (KF846 and EW49). Moreover, the spatial expression patterns in wheat response between plants inoculated with beneficial T. atroviride (AN35) and T. cremeum (AN392) were assessed. Understanding the sophisticated role of miRNAs in wheat–fungal interactions may initiate a discussion concerning the use of this knowledge to protect wheat plants from the harmful effects of fungal pathogens. With the use of droplet digital PCR (ddPCR), the absolute quantification of the selected miRNAs in the tested material was carried out. The differential accumulation of miR398, miR167, and miR159 in the studied groups was observed. The abundance of all analyzed miRNAs in the roots demonstrated an increase in the early and reduction in late wheat response to F. culmorum inoculation, suggesting the role of these particles in the initial wheat reaction to the studied fungal pathogen. The diverse expression patterns of the studied miRNAs between Trichoderma–inoculated or F. culmorum–inoculated plants and control wheat, as well as between Trichoderma–inoculated and F. culmorum–inoculated plants, were noticed, indicating the need for further analysis.
Experimental and Theoretical Investigations of a Modified Single-Slope Solar Still with an External Solar Water Heater
Authors: Alwan Naseer T. , Shcheklein Sergey E. , Ali Obed Majeed , Majeed Milia H. , Agyekum Ephraim Bonah 
Published: November 2021

One of the key impediments to the wide utilization of solar water desalination systems is limited production. Hence, this study aims at increasing the thermal performance of a single-slope solar still by increasing the surface area of evaporation and absorption exposed to sunlight. A hollow rotating cylinder was installed inside the still structure; this modified system was then joined with an outside solar water heater for productivity improvement. The obtained results show that a 0.5 rpm rotational speed ensured that the cylinder’s surface was kept wet. A mathematical model has been formulated using the finite difference method and the Fortran 90 programming language to assess the thermal performance productivity of two solar stills (conventional solar still (CSS) and modified solar still (MSS)) modelled under different conditions. The experimental and theoretical results are well agreed, with an error of 6.14%. The obtained results show that the maximum productivity recorded in July 2019 was about 11.1 L/m2 from the MSS and 2.8 L/m2 from the CSS, with an improvement rate ranging between 286% and 300% during June, July, August, and September 2019. The production cost per liter of distilled water from the modified and conventional solar stills was 0.0302 USD/L and 0.0312 USD/L, respectively, which indicates a noticeable reduction in the cost of distillate water production.
On a Generalized Convolution Operator
Authors: Sharma Poonam , Raina Ravinder Krishna , Sokół Janusz 
Published: November 2021

Recently in the paper [Mediterr. J. Math. 2016, 13, 1535–1553], the authors introduced and studied a new operator which was defined as a convolution of the three popular linear operators, namely the Sǎlǎgean operator, the Ruscheweyh operator and a fractional derivative operator. In the present paper, we consider an operator which is a convolution operator of only two linear operators (with lesser restricted parameters) that yield various well-known operators, defined by a symmetric way, including the one studied in the above-mentioned paper. Several results on the subordination of analytic functions to this operator (defined below) are investigated. Some of the results presented are shown to involve the familiar Appell function and Hurwitz–Lerch Zeta function. Special cases and interesting consequences being in symmetry of our main results are also mentioned.
Biofilm Formation and blaOXA Genes Detection Among Acinetobacter baumannii from Clinical Isolates in a Tertiary Care Kirtipur Hospital, Nepal
Authors: Ghimire Upasana , Kandel Rupesh , Neupane Mary , Shrestha Sanjit , K C Sudeep , Khanal Santosh , Joshi Dev Raj 
Published: November 2021

(1) Background: Acinetobacter baumannii has emerged as a leading cause of nosocomial infections as they are capable of evolving resistance to various classes of antibiotics. The ability of A. baumannii to form biofilm might also be associated with increased antibiotic resistance and hence treatment failure. This study was carried to associate the biofilm formation with the drug resistance pattern of A. baumannii and to detect blaOXA-23, blaOXA-24, and blaOXA-51 from carbapenem resistance isolates. (2) Methods: Among different clinical samples, a total of 19 Acinetobacter spp. were identified with conventional microbiological procedures. The biofilm production was determined by a quantitative adherence assay. The antimicrobial susceptibility test was carried out by the Kirby-Bauer disc diffusion method, carbapenemase production detection was confirmed by Modified Hodge Test. And target resistant genes were detected by polymerase chain reaction. (3) Results: Out of 90 clinical specimens, 64.44% (58/90) showed bacterial growth. Whereas, 32.75% (19/58) isolates were identified as A. baumannii. Among all A. baumannii isolates, 84.21% (16/19) were multidrug-resistance and 63.16% (12/19) carbapenem resistance phenotypically. blaOXA-51 was detected in all the isolates and blaOXA-23 was detected only in 63.16% (12/19) isolates. However, blaOXA-24 was not detected in any of the isolates. Among A. baumannii, 89.47% (17/19) isolates produced biofilm with 47.37% (9/19) strong biofilm producers. (4) Conclusions: In the majority of MDR A. baumannii, blaOXA-51 and blaOXA-23 were detected as the determinant factor for carbapenem resistance having a direct relation with biofilm formation. This study provided a valuable clue for the management of A. baumannii infections in clinical settings.
Perancangan Prototype Sistem Keamanan Parkir Otomatis Berbasis Radio Frequency Identification (RFID)
Authors: Rosmiati  , Pratama Hidayatullah , Arif Nuraeni 
Published: November 2021

Terjadinya kasus kehilangan kendaraan di wilayah kampus khususnya kendaraan roda dua dikarenakan oleh sistem pengawasan keluar masuk kendaraan yang masih menggunakan cara manual. Hal ini dapat mengganggu proses pembelajaran yang berjalan di kampus. Untuk meminimalisir terjadinya pencurian kendaraan dibutuhkan teknologi sistem keamanan parkir yang bekerja secara otomatis.
Prototype sistem keamanan parkir yang dirancang dalam penelitian ini menggunakan teknologi Radio Frequency Identifacation (RFID) yang terhubung dengan website. RFID ini berfungsi untuk mengidentifikasi pengunjung kampus. Metode identifikasi pada RFID ini menggunakan gelombang radio yang dapat mengirimkan data identitas objek secara nirkabel atau tanpa bantuan manusia. Prototype ini menggunakan RFID card, RFID reader, Sensor Ultrasonik HRC04, NodeMCU ESP32, Buzzer, Motor Servo, PHP, dan MYSQL.
Hasil dari penelitian ini berupa Prototype sistem keamanan parkir dengan menggunakan teknologi Radio Frequency Identification yang diharapkan dapat membantu petugas keamanan dalam mengawasi keamanan parkir di wilayah kampus.
Spatial suppression due to statistical regularities in a visual detection task
Authors: van Moorselaar Dirk , Theeuwes Jan 
Published: November 2021

AbstractIncreasing evidence demonstrates that observers can learn the likely location of salient singleton distractors during visual search. To date, the reduced attentional capture at high-probability distractor locations has typically been examined using so called compound search, in which by design a target is always present. Here, we explored whether statistical distractor learning can also be observed in a visual detection task, in which participants respond target present if the singleton target is present and respond target absent when the singleton target is absent. If so, this allows us to examine suppression of the location that is likely to contain a distractor both in the presence, but critically also in the absence, of a priority signal generated by the target singleton. In an online variant of the additional singleton paradigm, observers had to indicate whether a unique shape was present or absent, while ignoring a colored singleton, which appeared with a higher probability in one specific location. We show that attentional capture was reduced, but not absent, at high-probability distractor locations, irrespective of whether the display contained a target or not. By contrast, target processing at the high-probability distractor location was selectively impaired on distractor-present displays. Moreover, all suppressive effects were characterized by a gradient such that suppression scaled with the distance to the high-probability distractor location. We conclude that statistical distractor learning can be examined in visual detection tasks, and discuss the implications for attentional suppression due to statistical learning.
Analysis of High-precision TESS Photometry of the Black Hole X-Ray Binary Cygnus X-1: Evidence of Intrinsic Variability of the Luminous Blue Supergiant Component
Authors: Petretti Catherine , Guinan Edward 
Published: November 2021

Abstract
We report on Transiting Exoplanet Survey Satellite (TESS) high-precision photometry of the iconic non-eclipsing 5.60 days (O9.7Iab+black hole) binary Cygnus X-1. Previous ground-based photometry reveals low-amplitude (∼0.04 mag) ellipsoidal light-variations that arise from the tidal (and rotational) distortion of the O9.7Iab companion. Additional small light-variations have also been reported by many observers. Short-cadence TESS photometry was conducted over ∼27 days during 2019 July–August. The photometry shows the expected ∼5.60 days binary ellipsoidal variations, but in addition ∼0.01–0.03 mag complex quasi-periodic brightness variations. The observations were analyzed to investigate the underlying extra-binary variability. We also determined a new time of minimum light and calculated an updated period and light elements. The quasi-periodic, (non-binary) light-variations likely arise from the complex pulsations of the blue supergiant.
Un nombre en la torre de marfil. Psicoanálisis y psicología profunda a través de La historia interminable de M. Ende (1979)
Authors: Huertas Maestro Miguel 
Published: November 2021

El objetivo del artículo es abordar la relación entre psicoanálisis y arte -en este caso, literatura- entendiendo que este último arrastra intuiciones que posterior o paralelamente hipotetizadas por las disciplinas psi. Para ello, se parte del concepto de “arte visionario” de Carl Gustav Jung y de la noción de que el “artista precede” de Jacques Lacan para explorar la manera en la que una obra como La Historia Interminable (M. Ende) permite arrojar luz sobre los desarrollos teóricos de estos dos autores. En el caso de J. Lacan, los registros de lo simbólico, lo imaginario y lo real. En el caso de C. G. Jung, el viaje interior que supone el proceso de individuación y el contacto con arquetipos del inconsciente colectivo.
De las tertulias a la conspiración: la disputa por la belleza y las amistades peligrosas de Alejandro Malaspina en Madrid
Authors: Sánchez Arteaga Juan Manuel 
Published: November 2021

Este artículo revisa el periodo transcurrido por Malaspina en Madrid tras su “viaje alrededor del mundo”, hasta su detención en noviembre de 1795. A la luz de fuentes hasta ahora ignoradas por la historiografía malaspiniana, se analiza la participación de Malaspina en una disputa literaria en el Diario de Madrid, donde llegó a publicar bajo seudónimo cuatro cartas filosóficas sobre la belleza que constituyen un antecedente directo de su Meditación filosófica, su obra más personal, escrita en presidio tras su arresto. Por último, se analiza la relación de Malaspina con su vecina madrileña Fernanda O’Connock, marquesa de Matallana, mujer vinculada a la oposición política a Godoy y destacada agente conspiradora contra el primer ministro en dicho periodo, quien muy posiblemente tuvo un papel mucho más activo de lo que hasta ahora se le había reconocido en la conspiración Malaspina.
CD24 and IgM Stimulation of B Cells Triggers Transfer of Functional B Cell Receptor to B Cell Recipients Via Extracellular Vesicles
Authors: Phan Hong-Dien , Longjohn Modeline N , Gormley Delania J B , Smith Reilly H , Dang-Lawson May , Matsuuchi Linda , Gold Michael R , Christian Sherri L 
Published: November 2021

Abstract
Extracellular vesicles (EVs) are membrane-encapsulated nanoparticles that carry bioactive cargo, including proteins, lipids, and nucleic acids. Once taken up by target cells, EVs can modify the physiology of the recipient cells. In past studies, we reported that engagement of the glycophosphatidylinositol-anchored receptor CD24 on B lymphocytes (B cells) causes the release of EVs. However, a potential function for these EVs was not clear. Thus, we investigated whether EVs derived from CD24 or IgM-stimulated donor WEHI-231 murine B cells can transfer functional cargo to recipient cells. We employed a model system where donor cells expressing palmitoylated GFP (WEHI-231-GFP) were cocultured, after stimulation, with recipient cells lacking either IgM (WEHI-303 murine B cells) or CD24 (CD24 knockout mouse bone marrow B cells). Uptake of lipid-associated GFP, IgM, or CD24 by labeled recipient cells was analyzed by flow cytometry. We found that stimulation of either CD24 or IgM on the donor cells caused the transfer of lipids, CD24, and IgM to recipient cells. Importantly, we found that the transferred receptors are functional in recipient cells, thus endowing recipient cells with a second BCR or sensitivity to anti-CD24–induced apoptosis. In the case of the BCR, we found that EVs were conclusively involved in this transfer, whereas in the case in the CD24 the involvement of EVs is suggested. Overall, these data show that extracellular signals received by one cell can change the sensitivity of neighboring cells to the same or different stimuli, which may impact B cell development or activation.