bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotional Eating After Manipulating Emotion Regulation: A Laboratory Study in Adolescents
Authors: Debeuf Taaike , Verbeken Sandra , Volkaert Brenda , Michels Nathalie , Blechert Jens , Braet Caroline 
Published: October 2021

AbstractIt is often assumed that emotional eating occurs when an individual is unable to utilise emotion regulation (ER) to cope with stress. In this stress exposure study, we explored whether manipulating participants’ ER strategies (rumination or self-compassion) influenced their stress-related affect and food consumption. Fifty-three adolescents (Mage = 14.72) were included; half of the participants were instructed to use rumination as their ER strategy, and half were instructed to use self-compassion. We could not demonstrate that the ER strategies differently affected stress-related affect. However, we did find that increased Happiness following ER self-compassion predicted reduced High-Fat Sweet food consumption, whereas increased Happiness following ER rumination instead led to greater High-Fat Sweet food consumption. In participants who ruminated, food consumption reduced feelings of Frustration, but not Boredom or Happiness. Post-hoc exploration revealed that only ER self-compassion, not ER rumination, normalised levels of stress-related affect. The results highlight the need for more research into the complex relationship between ER strategies, affect states, and food types in their effect on emotional eating.
Powerless in the Virgin Islands: Emergency Department and Wound Care Clinic Utilization Following the 2017 Hurricanes Irma and Maria on St. Thomas, U.S. Virgin Islands
Authors: Christopher Kenneth E , Kitsantas Panagiota , Farrell-Sealey Sherla , Hunte-Ceasar Tai 
Published: October 2021

Abstract

Objective:
The main objective of this work was to characterize the prevalence of acute medical needs by examining emergency department (ED) and outpatient wound care clinic (WCC) visits before, during, and after the 2017 Hurricanes Irma and Maria, in St. Thomas, United States (U.S.) Virgin Islands.

Methods:
Descriptive statistics and logistic regression were used to assess associations between the occurrence of the storms and visits due to injuries and chronic conditions presented to the ED and WCC from September 1, 2016 to May 31, 2018.

Results:
ED visits increased and the rate of injury care was higher during the storms (12 patient visits per day) than before or after the storms (9 patient visits per day). WCC visits increased during (12%) and after the storms (45%), and were associated with patients 60 years and older. The odds of ED and WCC visits due to injury during the storms were significantly higher (odds ratio [OR]: 1.28, 95% confidence interval [CI]: 1.17, 1.40) than prior to the storms. The odds for visits due to injuries were 1.19 (95% CI: 1.12, 1.28) times higher after the storms.

Conclusions:
Increases occurred in ED and WCC visits for injury care during the storms and in WCC visits after the storms. Public health preparedness mandates understanding how major hurricanes impact the prevalence of acute medical needs, and the factors that influence decisions to seek medical care, in their wake.
PRESIDENTS AND THE CONDITIONAL CORE-SWING TARGETING OF THE NATIONAL SUBSIDY IN SOUTH KOREA, 1989–2018
Authors: Kim Wooseok 
Published: October 2021

AbstractIn this article, I present a theory of conditional core-swing targeting that focuses on the competition for majority control in legislative elections to explain how presidents use their strong budgetary powers to manipulate the distribution of the national subsidy in South Korea. Presidents whose parties already possess a legislative majority are expected to favor core municipalities to strengthen the foundations of their majority constituency, whereas those who seek majority control are predicted to prioritize swing municipalities in an effort to cross the majority threshold. Presidents are also anticipated to respond to the electoral cycle by shifting subsidies to riskier municipalities when elections approach. Using a novel data set on national subsidy allocations that spans three decades, I find evidence in favor of the hypotheses. This article demonstrates that the beneficiaries of distributive favoritism are not fixed, and that politicians can engage in complex and varied targeting strategies to achieve their objectives.
COVID-19 Contact Tracing and Privacy Rights in Ghana: A Critical Analysis of the Establishment of Emergency Communications System Instrument, 2020 (EI 63)
Authors: Gawu Delali A , Mensah Richard Obeng 
Published: October 2021

AbstractIn December 2019, the world woke up to the news of a novel coronavirus (COVID-19). Since then, governments across the globe have deployed various measures to contain the spread of the disease. The government of Ghana, among other measures, issued the Establishment of Emergency Communications System Instrument, 2020 (EI 63) to establish an emergency communications system to aid contact tracing during public health emergencies. This executive instrument has been criticized for illegally “legalizing” the breach of the privacy rights of electronic communications network subscribers in Ghana. This article critically analyses EI 63 in relation to the right to privacy of communication enshrined in Ghana's 1992 Constitution. It argues against the constitutionality of EI 63, calls for its revocation and replacement with an act of Parliament enacted with due regard for Ghana's legislative framework on the protection of the right to privacy of communication.
Coordinated control of a 3DOF cartesian robot and a shape memory alloy-actuated flexible needle for surgical interventions: a non-model-based control method
Authors: Liang Fan , Traughber Bryan J. , Biswas Tithi , Guo Gordon , Muzic Raymond F. , Podder Tarun K. 
Published: October 2021

SummarySuccess of any needle-based medical procedures depends on accurate placement of the needle at the target location. However, accurate targeting and control of flexible self-actuating (active) needle are challenging. We have developed a shape memory alloy-actuated flexible needle steered by a 3D Cartesian robot and performed a comparative study of four, non-model-based, coordinated control methodologies for the combined robot steering and flexible-needle insertion process for surgical interventions. Investigated four controllers are: proportional–integral–derivative (PID), PID with the cubic of positional error term (PID-P3), static PID sliding mode controller, and robust adaptive PID sliding mode controller (RAPID-SMC). Relative efficacies of these controllers are demonstrated by performing experiements using a tissue-mimicking soft material phantom. Results from experiments have reavealed that RAPID-SMC is superior to other three controllers.
Adult Day Program Directors’ Experiences Managing the COVID-19 Pandemic
Authors: Vervaecke Deanna , Owaisi Rumia B. , Meisner Brad A. 
Published: October 2021

AbstractAdult day programs (ADPs) provide community-based supervised recreational services to older adults living with chronic conditions and their caregivers. Most ADPs continued operating during the pandemic, tasking directors with the responsibility of managing the complexities of the coronavirus disease (COVID-19) pandemic. This study explored how ADP directors managed and experienced the COVID-19 pandemic. Semi-structured interviews were conducted with 18 ADP directors from a large health care region in Ontario. Thematic analysis resulted in four themes that detailed how participants: 1) responded to the pandemic with adapted services; 2) navigated the pandemic responses within systems and organizations, and with each other, clients, and caregivers; 3) felt personally during the pandemic; and 4) gained new insights on their clients and the importance of ADPs in the health care system due to the pandemic. Findings highlight pre-existing and emerging gaps and opportunities within ADP service provision for clients and caregivers, as well as service providers and directors.
Quantifying seed and establishment limitation to seedling recruitment of arable weeds: an example of barnyardgrass (Echinochloa crus-galli)
Authors: Selig Christian , de Mol Friederike , Westerman Paula R. , Gerowitt Bärbel 
Published: October 2021

AbstractThe establishment of plants in an ecosystem is limited by the availability of seeds and the availability of suitable sites for establishment. Describing plant population dynamics through the relative strength of seed and establishment limitation is an important concept in the study of natural ecosystems. To date, it is unclear whether this concept can be applied to describe populations of annual weeds in agricultural fields. Using a recruitment function, we show that limitation parameters prove valuable in describing seedling recruitment in weed populations. We conducted a seed addition experiment in three cornfields (Zea maysL.) and recorded seedling recruitment in populations of the economically important weed barnyardgrass [Echinochloa crus-galli(L.) P. Beauv.]. Seed predation, competition with other weeds, and seed burial were prevented. We estimated the strength of seed and establishment limitation in the population with two parameters:n, which is the number of microsites, andb, which is the suitability of those sites to support a seedling. We further estimated the relative proportions of density-dependent and density-independent establishment limitation in the seedling population. Recruitment rates ofE. crus-galliranged from 31% to 36% across all evaluated seed densities and fields, which is high compared with results from other seed addition studies. Two of the three monitored populations were predominantly establishment limited at the highest evaluated seed density of 2,400 added seeds m−2. Further knowledge about the relative strength of limitations in other weed populations will provide important information on how effective different weed management strategies can be.
The Southern Ocean Radiative Bias, Cloud Compensating Errors, and Equilibrium Climate Sensitivity in CMIP6 Models
Authors: Schuddeboom A. J. , McDonald A. J. 
Published: October 2021

AbstractCoupled Model Intercomparison Project Phase 6 (CMIP6) models are analyzed using an established cloud clustering methodology. This enables a comparison of cloud representation in models and observations. The simulation of stratocumulus clouds over the Southern Ocean is shown to have changed substantially from earlier generation models. The CMIP6 models analyzed show stratocumulus clouds now occur more often in simulations than in International Satellite Cloud Climatology Project (ISCCP) observations, but are not bright enough compared to Clouds and the Earth's Radiant Energy System (CERES) data. This is in contrast to the “too few, too bright” problem, which has characterized prior model simulations of stratocumulus clouds, particularly over the Southern Ocean. The cloud clusters also enable the calculation of mean and compensating shortwave cloud radiative effect (SW CRE) errors from model data. The compensating errors are shown to be much larger than mean errors suggesting the CMIP6 models still have much to improve in their cloud representation. A statistically significant negative relationship between the mean and compensating errors in SW CRE over the Southern Ocean is identified. This relationship is observed elsewhere, but is only significant over the Southern Ocean. This implies model tuning efforts are hiding biases in the representation of clouds in this region. CMIP6 models have been shown to have a higher equilibrium climate sensitivity (ECS) relative to CMIP5 simulations. The link between ECS and SW CRE mean and compensating errors is investigated but no evidence of a relationship between these variables was found.
TEC Map Completion Through a Deep Learning Model: SNP‐GAN
Authors: Pan Yang , Jin Mingwu , Zhang Shunrong , Deng Yue 
Published: October 2021

AbstractThe limited availability of ground receiver stations causes an approximate 52% of data gaps in Massachusetts Institute of Technology (MIT)‐ total electron content (TEC) global maps. The completed TEC maps are highly desirable for both scientific research and space weather applications. Compared to the conventional image inpainting methods, the deep learning methods using generative adversarial networks (GANs) offer an effective image inpainting tool. We adapt the Spectrally Normalized Patch GAN (SNP‐GAN) for the TEC map completion using a traditional complete TEC data source, the International Global Navigation Satellite System TEC (IGS‐TEC) maps, as the training data. For 10‐fold cross‐validation of 20‐year IGS‐TEC data, SNP‐GAN reduces the root mean squared error (RMSE) by more than 30% compared to our previous model, the deep convolutional GAN with Poisson blending (DCGAN‐PB). Two case studies using MIT‐TEC data for 2013 and 2016 storms also demonstrate that SNP‐GAN outperforms DCGAN‐PB in terms of recovering equatorial and low latitude TEC structures. Meanwhile, the end‐to‐end styled generator of SNP‐GAN saves time in the map completion step by avoiding iterative mapping used in DCGAN‐PB. Both deep learning methods not only preserve the large‐scale TEC structures well, but also reveal mesoscale (100–1,000 km) TEC structures that are missing in IGS‐TEC. This work represents an important progress for efficient and automatic TEC map completion with high accuracy.
A package for the automated classification of images containing supernova light echoes
Authors: Bhullar A. , Ali R. A. , Welch D. L. 
Published: October 2021

Context.The so-called light echoes of supernovae – the apparent motion of outburst-illuminated interstellar dust – can be detected in astronomical difference images; however, light echoes are extremely rare which makes manual detection an arduous task. Surveys for centuries-old supernova light echoes can involve hundreds of pointings of wide-field imagers wherein the subimages from each CCD amplifier require examination.Aims.We introduce ALED, a Python package that implements (i) a capsule network trained to automatically identify images with a high probability of containing at least one supernova light echo and (ii) routing path visualization to localize light echoes and/or light echo-like features in the identified images.Methods.We compared the performance of the capsule network implemented in ALED (ALED-m) to several capsule and convolutional neural networks of different architectures. We also applied ALED to a large catalogue of astronomical difference images and manually inspected candidate light echo images for human verification.Results.ALED-m was found to achieve 90% classification accuracy on the test set and to precisely localize the identified light echoes via routing path visualization. From a set of 13 000+ astronomical difference images, ALED identified a set of light echoes that had been overlooked in manual classification.
Synthesis of Purines and Related Molecules by Cyclization ­Reactions of Heterocyclic Enamines
Authors: Langer Peter 
Published: October 2021

AbstractA great variety of pharmacologically relevant fluorinated purine analogues are available by cyclization reactions of heterocyclic enamines with 1,3-dielectrophiles. The reactions usually proceed with excellent regioselectivities. As electrophiles, 1,3-diketones, enaminones or 3-chloro-2-en-1-ones were used. Other synthetic strategies are based on inverse-electron-demand Diels–Alder reactions of heterocyclic enamines with triazines. Purine analogues were further functionalized by transition-metal-catalyzed CH-coupling reactions or oxidative cyclizations, giving rise to more complex polycyclic products. Amidino-C-glycosides in their reactions with 1,3-dielectrophiles afforded pyrimidine-C-glycosides. Multicomponent reactions of heterocyclic enamines afforded complex products, including spirocyclic derivatives.1	Introduction2	1,3-Diketones3	Enaminones4	3-Chloro-2-en-1-ones5	Triazines6	Transition-Metal-Catalyzed Functionalizations7	Pyrimidine-C-Nucleosides8	Multicomponent Reactions9	Conclusions
“I Didn't Realize How Hard It Was Going to Be Just Transitioning Back into Life”: A Qualitative Exploration of Outcomes for Survivors of Pediatric Septic Shock
Authors: Clark Jonna D. , Kraft Stephanie A. , Dervan Leslie A. , Di Gennaro Jane L. , Hurson Jill , Watson Robert S. , Zimmerman Jerry J. , Meert Kathleen L. ,   for the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators
Published: October 2021

AbstractRecovery following pediatric critical illness is multifaceted and complex. While most critically ill children survive, many experience morbidities in physical, emotional, cognitive, and social function. We aimed to deeply explore and describe the multidimensional impact of pediatric septic shock for affected children and their families at the granular level using exploratory qualitative methodology. We performed semistructured telephone interviews of adolescents and caregivers of children admitted with community-acquired septic shock to two tertiary pediatric intensive care units in the United States. Interviews were conducted within two years of hospital admission, and were recorded, transcribed, and analyzed using thematic analysis. Two adolescents and 10 caregivers were interviewed. Participants described meaningful and long-lasting outcomes of septic shock on multiple dimensions of their lives. The adolescents and caregivers described substantial negative consequences on physical health and function which resulted in increased medical complexity and heightened caregiver vigilance. The physical impact led to substantial psychosocial consequences for both the child and family, including social isolation. Most caregivers expressed that septic shock was transformational in their lives, with some caregivers describing posttraumatic growth. This preliminary study provides a novel, granular view of the multidimensional impact of septic shock in pediatric patients and their families. Exploring these experiences through qualitative methodology provides greater insight into important patient and family outcomes. Deeper understanding of these outcomes may support the development of meaningful interventions to improve quality of life for children and their families following critical illness.
Cardiac reparative therapy with adipose graft transposition procedure (AGTP) improves electrophysiological remodeling of chronic myocardial infarction
Authors: Adelino Recasens R , Galvez-Monton C , Martinez-Falguera D , Curiel C , Teis A , Marsal R , Rodriguez-Leor O , Sarrias A , Bazan V , Fadeuilhe E , Villuendas R , Aranyo J , Bayes-Genis A , Bisbal F 
Published: October 2021

Abstract

Background
Cardiac regeneration is a promising therapeutic option for patients with prior myocardial infarction (MI). Adipose graft transposition procedure (AGTP) is a cardiac reparative therapy consisting of the transposition of a vascularized adipose flap from the autologous pericardium over the epicardial scar area, which has shown to reduce the infarct size and improve the left ventricular function.

Purpose
To assess the impact of the AGTP on the electrophysiological remodeling of the post-MI scar by means of electrophysiological study (EPS), high density (HD) mapping, and 3D contrast-enhanced MRI (ceMRI).

Methods
A lateral MI was induced in 14 Landrace X Large White pigs by coil deployment at the first marginal branch of the circumflex artery. A 3D ceMRI, EPS and endocardial HD mapping were performed 2 (baseline) and 6 weeks post-MI (30 day post-treatment). Subjects were randomized to AGTP (n=8) or sham surgery (n=6) following baseline tests. Voltage and activation maps were blindly analyzed off-line with self-customized ParaView-based software. ceMRI was post-processed with ADAS3D. Conventional bipolar and unipolar voltage cut-offs were used (0.5–1.5mV and 6.7mV, respectively). Conduction velocity (CV) was determined for every pair of contiguous points. Areas of CV were quantified for every 0.2m/s steps (&lt;0.2 - 4 m/s).

Results
At follow-up, and compared to the sham group, the AGTP group showed a significant reduction of the border zone area in both bipolar voltage mapping (−18±50% vs +10±144%, p=0.043) and ceMRI (−2.0±1.7 vs +1.1±2.8g; p=0.047), as well as a reduction in dense scar mass by ceMRI (−1.1±0.7g vs. +0.6±0.9 g, p=0.001). The AGTP group had a significant reduction of the size of very-slow CV areas (&lt;0.2 m/s), compared to the sham group (−3.5±3.4 vs. +1.5±3.8 mm2, p=0.022), without differences in other CV ranges. EPS did not induce ventricular tachycardia in any subject at baseline, and only in 1 of the sham group at the follow-up.

Conclusions
Cardiac reparative therapy with AGTP of post-MI scar reduced the size of border zone tissue and very-slow conduction zones and could provide a protective effect against arrhythmic events in ischemic heart disease.

Funding Acknowledgement
Type of funding sources: Public grant(s) – National budget only. Main funding source(s): FIS grant - Instituto de Salud Carlos III
Short homology-directed repair using optimized Cas9 in the pathogen Cryptococcus neoformans enables rapid gene deletion and tagging
Authors: Huang Manning Y , Joshi Meenakshi B , Boucher Michael J , Lee Sujin , Loza Liza C , Gaylord Elizabeth A , Doering Tamara L , Madhani Hiten D 
Published: October 2021

Abstract
Cryptococcus neoformans, the most common cause of fungal meningitis, is a basidiomycete haploid budding yeast with a complete sexual cycle. Genome modification by homologous recombination is feasible using biolistic transformation and long homology arms, but the method is arduous and unreliable. Recently, multiple groups have reported the use of CRISPR-Cas9 as an alternative to biolistics, but long homology arms are still necessary, limiting the utility of this method. Since the S. pyogenes Cas9 derivatives used in prior studies were not optimized for expression in C. neoformans, we designed, synthesized, and tested a fully C. neoformans-optimized (Cno) Cas9. We found that a Cas9 harboring only common C. neoformans codons and a consensus C. neoformans intron together with a TEF1 promoter and terminator and a nuclear localization signal (Cno CAS9 or “CnoCAS9”) reliably enabled genome editing in the widely used KN99α C. neoformans strain. Furthermore, editing was accomplished using donors harboring short (50 bp) homology arms attached to marker DNAs produced with synthetic oligonucleotides and PCR amplification. We also demonstrated that prior stable integration of CnoCAS9 further enhances both transformation and homologous recombination efficiency; importantly, this manipulation does not impact virulence in animals. We also implemented a universal tagging module harboring a codon-optimized fluorescent protein (mNeonGreen) and a tandem Calmodulin Binding Peptide-2X FLAG Tag that allows for both localization and purification studies of proteins for which the corresponding genes are modified by short homology-directed recombination. These tools enable short-homology genome engineering in C. neoformans.