bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physical examination, serum biochemical, and coagulation abnormalities, treatments, and outcomes for dogs with toxicosis from α-amanitin–containing mushrooms: 59 cases (2006–2019)
Authors: Kaae Jennifer A. , Poppenga Robert H. , Hill Ashley E. 
Published: February 2021

OBJECTIVE
To report history, physical examination findings, clinicopathologic abnormalities, treatments, and outcomes of dogs with confirmed α-amanitin toxicosis resulting from ingestion of α-amanitin–containing mushrooms, and to report whether any differences were significant between survivors and nonsurvivors.

ANIMALS
59 dogs.

PROCEDURES
Medical records of all dogs with confirmed α-amanitin toxicosis presented to a northern California emergency and specialty veterinary hospital between January 2006 and July 2019 were reviewed for signalment; body weight; history; physical examination findings including rectal temperature at presentation; results of serum biochemical analyses, coagulation tests, and a test for the detection of α-amanitin in urine; treatments; and outcomes. Differences for each were compared between survivors and nonsurvivors.

RESULTS
Among the 59 dogs, 36 were < 1 year of age; 56 had variable clinical signs that included vomiting, diarrhea, anorexia, and weakness or lethargy; and 22 had rectal temperatures > 39.2°C (102.5°F) at presentation. Cases were seen throughout the calendar year. At presentation, alanine aminotransferase activity was mildly to markedly increased in 97% of dogs, hypoglycemia was noted in 78%, and coagulation times were prolonged in 91%. Most dogs that rapidly decompensated died; however, 13 dogs survived to hospital discharge and completely recovered.

CONCLUSIONS AND CLINICAL RELEVANCE
Ability to recognize dogs with α-amanitin toxicosis on the basis of clinical signs, physical examination findings, and clinicopathologic test results is essential because mushroom ingestion is rarely observed and immediate treatment is necessary. Dogs that have marked hypoglycemia or coagulopathy may have a poor prognosis.
Intelligent Design and Imaginary Worlds in Cost-Effectiveness Claims: An Overview of Commentaries in INNOVATIONS in Pharmacy from July 2016 to February 2017
Authors: Langley Paul C 
Published: February 2021

Over the past 30 years, thousands of modeled cost-effectiveness studies have been published. Whether this effort has been worthwhile is debatable. For supporters of modeled cost-effectiveness studies, this effort has been worthwhile because the modeled claims are intended to inform health care decision makes. To opponents, the effort is seen as largely a waste of time because the claims are typically non-evaluable. Rather than subscribing to the standards of normal science in its focus on hypothesis testing through experimentation and replication, opponents have viewed practitioners in health technology assessment as being content to develop imaginary worlds with no thought to their role in practical decision-making. Given this ongoing commitment to constructing imaginary worlds, the purpose of this commentary is bring together the various commentaries, together with supporting publications that have appeared in INNOVATIONS in Pharmacy since mid-2016. This is in response to requests from faculty and graduate students at the College of Pharmacy, University of Minnesota for an overview of the arguments presented to date in support of a new research program that rejects imaginary constructs in favor of credible, evaluable and replicable claims to support formulary decision making.

Type: Commentary
Pemetaan Spectral Accelaration Daerah Yogyakarta Dengan Pendekatan Probabilistic Seismic Hazard Analysis
Authors: Nurhidayatullah Eka Faisal , Kurniati Dwi 
Published: February 2021

Daerah Istimewa Yogyakarta (DIY) memiliki tingkat aktivitas seismik yang tinggi, sudah berulang kali mengalami kejadian bencana gempa yang merugikan. Berbagai upaya untuk meminimalisir dampak bencana gempa bumi sudah dilakukan sebelumnya. Salah satunya yaitu dengan menerbitkan dan memperbaharui peta gempa secara berkala. Indonesia sedari lama menggunakan gempa sebagai acuan perencanaan infrastruktur, yaitu sejak tahun 1983 hingga yang terbaru yaitu peta gempa tahun 2017. Namun gempa berkekuatan 6,3 SR yang terjadi pada bulan Mei 2006 menunjukkan masih banyak bangunan terutama engineered yang hancur. Melihat begitu dahsyatnya dampak yang ditimbulkan oleh gempa tersebut maka mitigasi lebih lanjut terkait dengan bencana gempa perlu dilakukan untuk meminimalisir kerugian apabila bencana sejenis kembali terjadi dikemudian hari. Perlu dilakukan pembuatan peta gempa berskala mikro (daerah) guna perencanaan, estimasi kerusakan bangunan, korban jiwa dan kerugian secara ekonomi akibat kejadian gempa dimasa datang mengingat peta gempa yang dirilis pemerintah sampai saat ini masih berskala makro (nasional). Tujuan penelitian ini yaitu menganalisis angka percepatan tanah permukaan dengan luaran berupa peta gempa berskala mikro pada wilayah provinsi Yogyakarta. Data gempa diperoleh dari rekaman gempa dengan maksimum radius 500 km dari pusat kota Yogyakarta yang telah dipublikasi oleh USGS antara tahun 1900 sampai dengan 2020. Declustering dilakukan terhadap data historis dan sebaran peta gempa sehingga hanya digunakan gempa utama dengan magnitude ≥ 5 Mw. Dalam studi ini digunakan fungsi atenuasi Campel-Bozorgonia NGA (2008) untuk gempa Sesar, Atkinson-Boore Worldwide Data NGA (2003) intraslab dan interface untuk gempa subduksi benioff serta megahtrust. Nilai spectral acceleration (Sa) diperoleh dengan menggunakan pendekatan Probabilistic Seismic Hazard Analysis (PSHA). Hasil analisis probabilistik percepatan gerakan tanah kemudian dikembangkan menjadi peta pada beberapa periode ulang gempa. Berdasarkan hasil penelitian diperoleh peta probabilitas terlampaui 7% dalam 75 tahun didapatkan nilai spectral acceleration percepatan tanah puncak (PGA) berada dikisaran 0,525 – 0,688g, periode pendek 1,055 – 1,7g serta periode 1 detik 0,535 -0,695g. Pada peta probabilitas terlampaui 2% dalam 50 tahun diperoleh nilai spectral acceleration PGA yaitu 0,6 – 0,79g, periode pendek 1,325 – 2,1 g serta periode panjang 0,65 -0,85 g. Sedangkan pada peta probabilitas terlampaui 2% dalam 100 tahun, nilai spectral acceleration PGA berada diantara 0,66 – 0,86g, periode pendek 1,625 – 2,465g serta periode 1 detik 0,755 -0,995g. Tingkat aktivitas kegempaan pada klaster subduksi megathrust 1 serta sesar opak dilihat dari a-value, b-value serta Mc ditengarai memicu adanya peningkatan nilai spectral acceleration wilayah Yogyakarta dibanding peta hazard tahun 2017.
Perancangan Sistem Peringatan Longsor dan Deteksi Pergeseran Tanah Menggunakan Metode Telemetri
Authors: Sunardi Sunardi , Arifianto Teguh , Hartisa Anindira Listy , Darmawan Arief , Wirawan Willy Artha 
Published: February 2021

ABSTRACTDesign of Landslide Potential Warning System and Land Shifting Using Telemetry Method: According to the 2019 BNBP Performance Report, landslides are the fourth most frequent disaster in Indonesia, so we need a telemetry tool for land shifting. This system consists of ATMega328 Microcontroller, Linear Variable Differential Transformer sensor and rheostat, accelerometer sensor, rain gauge tipping bucket, and HC-12 wireless communication module. Normally, LVDT sensor reads ground shift in the 0-20 mm range, rheostat shifting up to 66 mm, accelerometer sensor reads data less than 20 deg and rain gauge tipping bucket sensor generates the amount of rainfall below 50 mm/hour which is sent data regularly to user. Warning alarms installed in these prone area will sound if the LVDT sensor reads ground shift30 mm, rheostat51 mm, accelerometer sensor reads data more than 45°, and rain gauge tipping bucket sensor reads more than 70 mm/hour. This test produces measurable parameter data so that it can be displayed and provide warning information.Keywords: alarm warning; ATMega 328; land shifting; landslides; telemetry.ABSTRAKMenurut Laporan Kinerja BNBP 2019, tanah longsor merupakan bencana yang sering terjadi urutan keempat di Indonesia, sehingga perlu suatu alat telemetri terhadap pergeseran tanah. Sistem ini terdiri atas Mikrokontroler ATMega328, sensor Linear Variable Differential Transformer dan rheostat, sensor accelerometer, sensor rain gauge tipping bucket, dan modul komunikasi wireless HC-12. Normalnya, sensor LVDT membaca pergeseran tanah pada range 0-20 mm, rheostat mampu melakukan pergeseran hingga 66 mm, sensor accelerometer membaca data kurang dari 20 deg, dan sensor rain gauge tipping bucket menghasilkan jumlah curah hujan dibawah 50 mm/jam yang kemudian data dikirim secara rutin ke user. Alarm peringatan yang terpasang di daerah rawan tersebut akan berbunyi jika sensor LVDT membaca pergeseran tanah 30 mm, rheostat 51 mm, sensor accelerometer membaca data lebih dari 45 derajat, dan sensor rain gauge tipping bucket membaca data lebih dari 70 mm/jam. Pengujian ini menghasilkan data parameter yang terukur sehingga dapat ditampilkan dan memberikan informasi peringatan.Kata Kunci: alarm peringatan; ATMega 328; pergeseran tanah; tanah longsor; telemetri
Dampak Kebijakan Pembatasan Kegiatan Akibat Covid-19 Terhadap Kecepatan Perjalanan di Wilayah Sarbagita Dengan Menggunakan Google Maps Distance Matrix API
Authors: Sukmayasa I Made , Ariyanti Octaviani 
Published: February 2021

ABSTRACTThe Impact of the Covid -19 Activity Restriction Policy on Speed in Sarbagita Area Using Google Maps Distance Matrix API: The Sarbagita area has variations in dealing with Covid-19 with saveral policies from limiting community activities to implementing the concept of a new normal where international tourism and education mobility excluded. This policy certainly has an impact on the activities of travelers. Data collection was performed using the Google Maps Distance Matrix API to obtain travel speed data for 24 hours from 22 June to 8 September 2020. Descriptive quantitative analysis was deployed to explain speed variations through tables and graphs. Based on data analysis, it was found that at the beginning of the policy the average travel speed in the Sabagita area was higher than the travel speed after the restriction policy ended with decrease 0.4%-2.4%. In addition, there is fluctuation in peak hours based on travel speed data at the beginning of the implementation of the travel restriction policy and there is a equalibrium of activity travel patterns in which origin and destination due to the activities of the traveler has stabilized after the policy allows domestic tourists to go to Bali Island. These results are very important as material for evaluating policies that have been implemented regarding Covid-19 and transportation management in order to gain optimal results.Keywords: Covid-19; travel speed; google maps distance matrix API.ABSTRAKDaerah Sarbagita memiliki variasi dalam menghadapi Covid-19 dengan beberapa kebijakan dari pembatasan kegiatan masyarakat sampai dengan penerapan konsep tatanan kehidupan baru di wilayah bali dimana sektor pariwisata dan pendidikan masih belum berjalan. Kebijakan ini tentunya berdampak pada aktivitas pelaku perjalanan. Pengumpulan data dilakukan dengan menggunakan Google Maps Distance Matrix API untuk mendapatkan data kecepatan perjalanan selama 24 jam dari tanggal 22 Juni-8 September 2020. Analisa kuantitatif deskriptif digunakan untuk memperoleh hasil kecepatan melalui tabel dan grafik. Dari hasil analisa data diperoleh bahwa pada awal kebijakan kecepatan perjalanan rata rata di wilayah Sabagita lebih tinggi dari pada kecepatan perjalanan setelah kebijakan pembatasan berakhir dimana kecepatan menurun sebesar 0.4%-2.4%. Selain itu, terjadi fluktuasi terhadap jam sibuk berdasarkan data kecepatan perjalanan pada awal penerapan kebijakan pembatasan perjalanan dan terjadinya keseimbangan pola perjalanan dimana asal dan tujuan akibat aktivitas pelaku perjalanan kembali stabil setelah kebijakan diizinkannya wisatawan domestik menuju Pulau Bali. Hasil ini sangat penting sebagai bahan evaluasi terhadap kebijakan yang telah diterpakan terkait Covid-19 dan manajemen transportasi untuk memperoleh hasil yang optimal. Kata Kunci: Covid-19; kecepatan perjalanan; google maps distance matrix API
Dampak Ekonomi Pengoperasian Transjakarta Ditinjau dari Persepsi Pengguna
Authors: Rita Kurniati Ni Luh Wayan 
Published: February 2021

ABSTRACTEconomic Impacts of Transjakarta Operation Judging from User Perception: The Provincial Government of DKI Jakarta has used a service purchase scheme for public transport operators known as Buy The Service. In this study, an analysis of the Transjakarta passenger perception index will be carried out in terms of the economic impact of the Transjakarta operation using cross tabulation analysis and community satisfaction index. The perception of 461 Transjakarta users shows that the value of Transjakarta services is 85.69 with very good criteria which indicates that Transjakarta users feel happy seen from the economic impact with the lowest average repair value, the lowest average value, the value, the lowest average score, the lowest, 3.8 integration between transportation, and the range of Transjakarta service areas. Keywords: Transjakarta; Buy The Service; Perception Index.ABSTRAKPemerintah Provinsi DKI Jakarta telah menggunakan skema pembelian pelayanan kepada pihak operator angkutan umum yang di kenal dengan istilah Buy The Service. Pada penelitian ini, dilakukan analisis terhadap indeks persepsi penumpang Transjakarta ditinjau dari dampak ekonomi dari pengoperasian Transjakarta menggunakan analisis tabulasi silang dan indeks kepuasan masyarakat. Persepsi dari 461 pengguna Transjakarta menunjukkan bahwa nilai pelayanan Transjakarta sebesar 85,69 dengan kriteria sangat baik yang mengindikasikan bahwa pengguna Transjakarta merasa bahagia dilihat dari dampak ekonomi dengan nilai rata-rata tertinggi sebesar 3,85, Nilai terendah dan harus mendapat perhatian fokus perbaikan, yaitu integrasi antar angkutan, dan jangkauan wilayah pelayanan Transjakarta.Kata Kunci: Transjakarta; Buy The Service; Indek Persepsi
Standard values for temporal muscle thickness in the Japanese population who undergo brain check-up by magnetic resonance imaging
Authors: Katsuki Masahito , Narita Norio , Sasaki Keisuke , Sato Yoshimichi , Suzuki Yasuhiro , Mashiyama Shoji , Tominaga Teiji 
Published: February 2021

Background:Skeletal muscle mass is an important factor for various diseases’ outcomes. The psoas muscle cross-sectional area on the abdominal computed tomography (CT), gait speed, and handgrip strength is used to measure it. However, it is difficult to measure the neurological patients’ muscle mass or function because (1) we do not perform abdominal CT. (2) Such patients have impaired consciousness, gait disturbance, paresis, and need of rest. Temporal muscle thickness (TMT) on magnetic resonance imaging (MRI) is now attractive for skeletal muscle volume indicator, but the reference values are not established. We herein investigated the standard value of the Japanese TMT using the brain check-up database by MRI.Methods:We retrospectively investigated 360 Japanese individuals from two institutions between 2017 and 2019. We measured TMT on the T1-weighted images in the previously reported way. The associations between TMT and other variables were analyzed.Results:TMT of 214 women and 146 men, ranging from 35 to 84 years old, was investigated. TMT ranged from 3.69 to 16.90 mm. Mean TMT values were significantly higher in men compared to women except for the over 70-year-old cohort. TMT was correlated to weight and body mass index in both sexes.Conclusion:This is the first retrospective study on the standard TMT values from the Japanese brain check-up database. Our results were just reference values, but these would be useful for further investigation in other neurosurgical and neurological diseases regarding muscle volume or sarcopenia.
Seizure outcome in moyamoya after indirect revascularization in pediatric patients: Retrospective study and literature review
Authors: Alramadan Abdullah , Ul Haq Anwar , Basindwah Sarah , Alshail Essam 
Published: February 2021

Background:
Moyamoya disease (MMD) is a unique cerebrovascular disorder characterized by progressive stenosis of anterior cerebral circulation. Moyamoya is not an uncommon disease in Saudi Arabia. Although a less common symptom of the disease, the incidence of seizure in MMD ranges from 6 to 30%. Indirect revascularization through Encephaloduroarteriosynangiosis technique is one of the surgical treatment options for MMD. In our cohort, we aim to evaluate seizure outcome in pediatric patients with moyamoya.

Methods:
Eleven patients with seizure as primary presentation for MMD over a period of 10 years were included in the study. All patients underwent EDAS surgery. All patients underwent pre- and postoperative assessment of multiple factors contributing to seizure outcome. Patients were evaluated for surgery control clinically and radiologically.

Results:
About 73% of MMD patients with seizures improved after EDAS surgery (P < 0.0005). Six patients out of 11 became seizure free. Patients with bilateral involvement of disease undergoing bilateral surgery had better seizure control than those undergoing unilateral surgery (P < 0.07).

Conclusion:
Patients with controlled seizure before surgery are more likely to be seizure free after intervention. Seizure outcome is favorable after indirect surgical revascularization in pediatric moyamoya patients.
A surgical case of C1 arch stenosis: A case report and review of literature
Authors: Yunoki Masatoshi 
Published: February 2021

Background:
Isolated symptomatic cervical stenosis of the atlas is quite rare; there have been 11 cases reported in literature.

Case Description:
A 76-year-old male presented with myelopathy attributed to C1 arch stenosis. Neuroimaging studies revealed posterior atlas compression of the spinal cord. Following a cervical laminectomy involving excision of the arch of the atlas, and the patient’s symptoms resolved.

Conclusion:
C1 stenosis resulting in cervical myelopathy due to posterior compression from the arch of the atlas is easily missed. Notably, C1 arch laminectomy may be very effective in resolving this entity.
Snowfall reduces the risk of chronic subdural hematoma onset: Analysis of an administrative database in Japan
Authors: Oda Kazunori , Aso Shotaro , Hattori Yujiro , Yamaguchi Fumio , Matsui Hiroki , Fushimi Kiyohide , Yasunaga Hideo , Morita Akio 
Published: February 2021

Background:
Chronic subdural hematoma (CSDH) is a frequently observed disease in neurosurgical practice. Although first snowfall has been considered to increase the onset of CSDH, few reports have assessed the relationship between snowfall and CSDH. In this study, we aimed to investigate the relationship between CSDH onset and first snowfall events.

Methods:
This retrospective study was based on the Japanese Diagnosis Procedure Combination inpatient database from July 1, 2010, to March 31, 2016, and on the global observation of snowfall events in Japan obtained from the Japan Meteorological Agency. We used a binomial approximation to evaluate the average number of CSDH patients after first snowfall events compared with that before first snowfall events. We calculated the odds ratio of CSDH onset on the first snowfall.

Results:
We identified 8526 CSDH patients from the database. A total of 5573 (65.4%) were observed before first snowfall events, and 2953 (34.6%) after first snowfall events. The first snowfall of winter was significantly associated with a reduction in the occurrence of CSDH (odds ratio, 0.53; 95% confidence interval; 0.51–0.55). In subgroup analysis, only the first snowfall in October was not associated with reduction in the occurrence of CSDH.

Conclusion:
First snowfall events did not affect the onset of CSDH in Japan.
Computed tomographic analysis of cervical spine pedicles in the adult Indian population
Authors: Kumar Sanjeev , Saini Naresh Kumar , Singh Devender , Chadha Manish , Mehrotra Gopesh 
Published: February 2021

Background:
Cervical pedicle screw insertion is a technically demanding procedure that carries the risk of catastrophic damage to surrounding neurovascular structures. Here, we analyzed computed tomography (CT)-based three-dimensional cervical spine pedicle geometry to determine the level and sex-specific morphologic differences in the adult Indian population.

Methods:
The CT scans of 200 patients (2400 pedicles) without significant cervical spine pathology were collected. The mean pedicle width (PW), pedicle height (PH), pedicle axial length (PAL), and pedicle transverse angle (PTA) from C2 to C7 were measured.

Results:
The smallest mean PW was at C3 in both males (4.85 ± 0.73 mm) and females (4.31 ± 0.43 mm); 7.08% of all pedicles were found to have mean PW of <4 mm. The smallest mean PH was at C5 in both males (6.25 ± 0.67mm) and females (5.54 ± 0.52 mm). The smallest mean PAL was at C2 in both males (27.46 ± 1.69mm) and females (25.90 ± 1.88 mm). The mean PW, PH, and PAL were significantly greater in males than females at all levels (P < 0.05). The smallest mean PTA was at C3 in males (41.79 ± 2.53°) and at C7 in females (42.40 ± 2.27°).

Conclusion:
In the adult Indian population, the PW, PH and PAL were smaller than in the typical western population. Females had even smaller PW, PH and PAL as compared to males. We recommend that a small inventory of 3.5mm screws between 20mm to 30mm length be used in most cases where cervical pedicle screws are being used in the Indian population. However, individual vertebrae should be screened preoperatively with CT scans to exclude gross anatomical variations, especially in females and at the C3 and C4 levels.
Preoperative simulation of a middle cerebral artery aneurysm clipping using a rotational three-dimensional digital subtraction angiography
Authors: Kimura Yuiko , Mashiko Toshihiro , Watanabe Eiju , Kawai Kensuke 
Published: February 2021

Background:
In recent years, young neurosurgeons have had few opportunities to gain experience with clipping surgeries. The first author was sometimes surprised that she could not predict the anatomical relationships between the aneurysm and vessels during actual surgery. This study investigated the differences between the expected and actual operative findings during clipping surgery for aneurysms of the middle cerebral artery.

Methods:
Medical records for 15 patients who underwent rotational three-dimensional (3D) digital subtraction angiography (3D-DSA) before the clipping surgery were analyzed after the surgery. The anatomical relationships between the aneurysm and parent arteries were defined by the intraoperative findings just before clipping. The viewing direction to obtain this definitive perspective (virtual viewing direction) was measured. The angle between this viewing direction and the coordinate axis was denoted as the “virtual angle for clipping (VAC).”

Results:
The VAC between the X-axis and viewing direction on the XY-plane (VAC-XY) ranged from –43° to +73° (mean, +27°), and the angle between the XY-plane and viewing direction (VAC-Z) ranged from +25° to –34° (mean, 5.5°). The difference between the VAC-XY and mean angle was significantly larger in cases with hidden branches behind the aneurysm. In these cases, the virtual viewing direction visualized the neck of the aneurysm. There is no correlation between M1 length and VAC-XY or VAC-Z discrepancy.

Conclusion:
3D-DSA or 3D computed tomography angiography images visualizing the neck of the aneurysm should be obtained in combination with images obtained from the standard oblique angle.