bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post-traumatic intracranial pseudo-aneurysms of posterior circulation: a comprehensive review of an under-diagnosed and rare entity
Authors: Palmieri Mauro , Pesce Alessandro , Zancana Giuseppa , Armocida Daniele , Maiese Aniello , Cirelli Carlo , Santoro Antonio , Frati Paola , Fineschi Vittorio , Frati Alessandro 
Published: October 2021

AbstractTraumatic aneurysms are rare and the total number of cases involving the posterior circulation (TIPC) is even smaller. Traumatic brain injury (TBI) may be responsible not only of rupture in brain aneurysm (BrA) pre-existing to trauma, but it has been identified also as a possible pathogenetic cause of TIPC formation in patients not affected by intracranial vascular lesions. A complete literature review was performed of all reported cases regarding rupture of BrA with SAH resulting from TIPC not previously identified at the first radiological screening. A representative case of a left posterior inferior cerebellar artery (PICA) pseudo-aneurysm caused by left vertebral artery’s dissection is reported. We show a unique complete collection of all 34 cases. Despite their rarity, TIPCs are associated with a significant morbidity and mortality rate, as high as 40–60%. Of the 22 patients with good neurological status (64.7%), we did not notice a significant correlation with regard to the location of the aneurysm, type of treatment, or clinical onset. Early recognition of a pseudo-aneurysm and adequate treatment seem to be the most important prognostic factor for these patients. Despite their rarity, TIPCs are associated with a significant morbidity and mortality rate. A TIPC should be suspected in case of delayed deterioration in head‐injured patient and should be investigated with angiography. Conservative management is worsened by poor prognosis and the goal of treatment is to exclude the aneurysm from circulation with surgical or endovascular methods as soon as possible.
Evaluation of field visit planning heuristics during rapid needs assessment in an uncertain post-disaster environment
Authors: Hakimifar Mohammadmehdi , Balcik Burcu , Fikar Christian , Hemmelmayr Vera , Wakolbinger Tina 
Published: October 2021

AbstractA Rapid Needs Assessment process is carried out immediately after the onset of a disaster to investigate the disaster’s impact on affected communities, usually through field visits. Reviewing practical humanitarian guidelines reveals that there is a great need for decision support for field visit planning in order to utilize resources more efficiently at the time of great need. Furthermore, in practice, there is a tendency to use simple methods, rather than advanced solution methodologies and software; this is due to the lack of available computational tools and resources on the ground, lack of experienced technical staff, and also the chaotic nature of the post-disaster environment. We present simple heuristic algorithms inspired by the general procedure explained in practical humanitarian guidelines for site selection and routing decisions of the assessment teams while planning and executing the field visits. By simple, we mean methods that can be implemented by practitioners in the field using primary resources such as a paper map of the area and accessible software (e.g., Microsoft Excel). We test the performance of proposed heuristic algorithms, within a simulation environment , which enables us to incorporate various uncertain aspects of the post-disaster environment in the field, ranging from travel time and community assessment time to accessibility of sites and availability of community groups. We assess the performance of proposed heuristics based on real-world data from the 2011 Van earthquake in Turkey. Our results show that selecting sites based on an approximate knowledge of community groups’ existence leads to significantly better results than selecting sites randomly. In addition, updating initial routes while receiving more information also positively affects the performance of the field visit plan and leads to higher coverage of community groups than an alternative strategy where inaccessible sites and unavailable community groups are simply skipped and the initial plan is followed. Uncertainties in travel time and community assessment time adversely affect the community group coverage. In general, the performance of more sophisticated methods requiring more information deteriorates more than the performance of simple methods when the level of uncertainty increases.
Hitchhiking or hang gliding? Dispersal strategies of two cereal-feeding eriophyoid mite species
Authors: Majer Agnieszka , Laska Alicja , Hein Gary , Kuczyński Lechosław , Skoracka Anna 
Published: October 2021

AbstractDispersal shapes the dynamics of populations, their genetic structure and species distribution; therefore, knowledge of an organisms’ dispersal abilities is crucial, especially in economically important and invasive species. In this study, we investigated dispersal strategies of two phytophagous eriophyoid mite species:Aceria tosichella(wheat curl mite, WCM) andAbacarus hystrix(cereal rust mite, CRM). Both species are obligatory plant parasites that infest cereals and are of economic significance. We investigated their dispersal success using different dispersal agents: wind and vectors. We hypothesised that in both mite species the main mode of dispersal is moving via wind, whereas phoretic dispersal is rather accidental, as the majority of eriophyoid mite species do not possess clear morphological or behavioural adaptations for phoresy. Results confirmed our predictions that both species dispersed mainly with wind currents. Additionally, WCM was found to have a higher dispersal success than CRM. Thus, this study contributes to our understanding of the high invasive potential of WCM.
Blockchain-enabled real-time SLA monitoring for cloud-hosted services
Authors: Khan Kashif Mehboob , Arshad Junaid , Iqbal Waheed , Abdullah Sidrah , Zaib Hassan 
Published: October 2021

AbstractCloud computing is an important technology for businesses and individual users to obtain computing resources over the Internet on-demand and flexibly. Although cloud computing has been adopted across diverse applications, the owners of time-and-performance critical applications require cloud service providers’ guarantees about their services, such as availability and response times. Service Level Agreements (SLAs) are a mechanism to communicate and enforce such guarantees typically represented as service level objectives (SLOs), and financial penalties are imposed on SLO violations. Due to delays and inaccuracies caused by manual processing, an automatic method to periodically verify SLA terms in a transparent and trustworthy manner is fundamental to effective SLA monitoring, leading to the acceptance and credibility of such service to the customers of cloud services. This paper presents a blockchain-based distributed infrastructure that leverages fundamental blockchain properties to achieve immutable and trustworthy SLA monitoring within cloud services. The paper carries out an in-depth empirical investigation for the scalability of the proposed system in order to address the challenge of transparently enforcing real-time monitoring of cloud-hosted services leveraging blockchain technology. This will enable all the stakeholders to enforce accurate execution of SLA without any imprecisions and delays by maintaining an immutable ledger publicly across blockchain network. The experimentation takes into consideration several attributes of blockchain which are critical in achieving optimum performance. The paper also investigates key characteristics of these factors and their impact to the behaviour of the system for further scaling it up under various cases for increased service utilization.
Mint: MDL-based approach for Mining INTeresting Numerical Pattern Sets
Authors: Makhalova Tatiana , Kuznetsov Sergei O. , Napoli Amedeo 
Published: October 2021

AbstractPattern mining is well established in data mining research, especially for mining binary datasets. Surprisingly, there is much less work about numerical pattern mining and this research area remains under-explored. In this paper we proposeMint, an efficient MDL-based algorithm for mining numerical datasets. The MDL principle is a robust and reliable framework widely used in pattern mining, and as well in subgroup discovery. InMintwe reuse MDL for discovering useful patterns and returning a set of non-redundant overlapping patterns with well-defined boundaries and covering meaningful groups of objects.Mintis not alone in the category of numerical pattern miners based on MDL. In the experiments presented in the paper we show thatMintoutperforms competitors among which IPD,RealKrimp, andSlim.
Using structural equation modelling for understanding relationships influencing the middle school technology teacher’s attitudes toward STEAM education in Korea
Authors: Kim Young-Heung , Na Seung-Il 
Published: October 2021

AbstractThe purpose of this study was to investigate the structural relationship between technology teachers’ attitudes toward STEAM education and the cooperation of instructional resources collaboration, school educational change receptivity, and instructional expertise and instructional efficacy. The population comprised about 3500 technology teachers working in middle schools in Korea, and the sample size was set at 650. Data were collected in parallel with postal surveys and online surveys. A total of 650 copies were distributed, of which 409 were recovered, and 283 copies were used for analysis after data cleaning. The Mplus 7 program was used for data analysis, and the significance level was set at 5%. First, we found that the suitability of the structural model established to clarify technology teachers’ attitudes toward STEAM education, instructional resource collaboration, school educational change receptivity, instructional expertise, and instructional efficacy was generally good, so the relationship between the variables was reasonably confirmed. Second, school educational change receptivity and instructional efficacy were found to have a direct effect on attitudes toward STEAM education. Third, the teachers’ instructional resources collaboration was confirmed to influence their attitudes toward STEAM education by mediating the school educational change receptivity and instructional efficacy, and their instructional expertise mediated their instructional efficacy. Fourth, school educational change receptivity was confirmed to influence attitudes toward STEAM education through the dual media of instructional expertise and instructional efficacy. Finally, instructional resource collaboration was confirmed to influence attitudes toward STEAM education through school educational change receptivity, instructional expertise, and instructional efficacy.
Is group work beneficial for producing creative designs in STEM design education?
Authors: Han Ji , Park Dongmyung , Hua Min , Childs Peter R. N. 
Published: October 2021

AbstractCreativity is a significant element in design education, and frequently a significant competency during recruitment for design professions. Group work and individual work are widely employed in higher education. Many studies have highlighted the merits of employing group work in design education, cultivating collaborative design abilities and fostering sought-after employability skills. Although the benefits of group work in design practice and education are widely recognised, few studies have shown evidence that group work outperforms individual work regarding creative design activities in higher education contexts. Therefore, the aim of this research is to explore whether group or individual work is more beneficial for fostering students in generating creative designs in STEM design education. A case study, involving two cohorts of second-year undergraduate students studying a UK Engineering degree Industrial Design programme, is reported. The case study compares the design outputs produced by the two cohorts tackling the same design challenge in a product design module but employing individual and group work, respectively. The case study results show that no significant differences have been found between the design outputs produced by group work and individual work, considering novelty, usefulness and overall creativity. Further analysis reveals that a student’s academic performance is not significantly related to the level of creativity of the design produced. This research indicates design educators should employ both group and individual work to complement each other in design education, and suggests potential solutions to enhance students’ design creativity.
Stereotactic radioablation for the treatment of ventricular tachycardia: preliminary data and insights from the STRA-MI-VT phase Ib/II study
Authors: Carbucicchio Corrado , Andreini Daniele , Piperno Gaia , Catto Valentina , Conte Edoardo , Cattani Federica , Bonomi Alice , Rondi Elena , Piccolo Consiglia , Vigorito Sabrina , Ferrari Annamaria , Pepa Matteo , Giuliani Mattia , Mushtaq Saima , Scarà Antonio , Calò Leonardo , Gorini Alessandra , Veglia Fabrizio , Pontone Gianluca , Pepi Mauro , Tremoli Elena , Orecchia Roberto , Pompilio Giulio , Tondo Claudio , Jereczek-Fossa Barbara Alicja 
Published: October 2021

Abstract
Purpose
We present the preliminary results of the STRA-MI-VT Study (NCT04066517), a spontaneous, phase Ib/II study, designed to prospectively test the safety and efficacy of stereotactic body radiotherapy (SBRT) in patientswith advanced cardiac disease and intractable ventricular tachycardia (VT).

Methods
Cardiac computed tomography (CT) integrated by electroanatomical mapping was used for substrate identification and merged with dedicated CT scans for treatment plan preparation. A single 25-Gy radioablation dose was delivered by a LINAC-based volumetric modulated arc therapy technique in a non-invasive matter. The primary safety endpoint was treatment-related adverse effects during acute and long-term follow-up (FU), obtained by regular in-hospital controls and implantable cardioverter defibrillator (ICD) remote monitoring. The primary efficacy endpoint was the reduction at 3 and 6 months of VT episodes and ICD shocks.

Results
Seven out of eight patients (men; age, 70 ± 7 years; ejection fraction, 27 ± 11%; 3 ischemic, 4 non-ischemic cardiomyopathies) underwent SBRT. At a median 8-month FU, no treatment-related serious adverse event occurred. Three patients died from non-SBRT-related causes. Four patients completed the 6-month FU: the number of VT decreased from 29 ± 33 to 11 ± 9 (p = .05) and 2 ± 2 (p = .08), at 3 and 6 months, respectively; shocks decreased from 11 to 0 and 2, respectively. At 6 months, all patients. showed a significant reduction of VT episodes and no electrical storm recurrence, with the complete regression of iterative VTs in 2/2 patients.

Conclusion
The STRA-MI-VT Study suggests that SBRT can be considered an alternative option for the treatment of VT in patients with structural heart disease and highlights the need for further clinical investigation addressing safety and efficacy.
Linking Availability Expectations, Bidirectional Boundary Management Behavior and Preferences, and Employee Well-Being: an Integrative Study Approach
Authors: Reinke Kathrin , Gerlach Gisela I. 
Published: October 2021

AbstractInformation and communication technologies enable employees to be available anywhere and anytime, raising availability expectations of work and nonwork contacts. Building on the theory of planned behavior and the person-environment fit theory, the present study examines how others’ availability expectations predict employees’ management of work and nonwork boundaries, and how these bidirectional boundary management behaviors relate to well-being. Results of structural equation modeling with data from 401 employees collected in two waves show that availability expectations of both coworkers and nonwork contacts predict how employees manage the boundaries of work and nonwork domains. Thereby, availability expectations are negatively related to segmentation of the two domains and coworkers' expectations show an indirect effect on employee well-being. Further, our study shows that work-nonwork and nonwork-work segmentation behavior have divergent effects on employee well-being, indicating that asymmetric boundary management behavior with high work-nonwork segmentation and low nonwork-work segmentation may be beneficial. Besides, moderation analyses underline the importance of enabling individuals to align their boundary management preferences with their actual behavior, especially when individuals have high work-nonwork segmentation preferences. By integrating and unveiling distinct antecedents of work-nonwork and nonwork-work segmentation behavior and their divergent effects on well-being, the present study contributes to a comprehensive framework for investigating and understanding bidirectional boundary management in the face of technology-enabled availability.
Hermaphroditism in fish: incidence, distribution and associations with abiotic environmental factors
Authors: Pla Susanna , Maynou Francesc , Piferrer Francesc 
Published: October 2021

AbstractThe distribution of hermaphroditism in fishes has traditionally been mainly explained by its dependence on biotic factors. However, correlates with major abiotic factors have not been investigated on a quantitative basis and at a global scale. Here, we determined the incidence of hermaphroditism in fish at the family and species level, tested the hypothesis that evolutionary relationships account for the poor presence of hermaphroditism in freshwater species, and tested the association of sexual systems with latitude, habitat type and depth. Functional hermaphroditism is reported in 8 orders, 34 families and 370 species of fishes, all teleosts. Sequential hermaphroditism predominates over simultaneous hermaphroditism at a ratio ~ 5:1 and protogyny (female-to-male sex change) predominates ~ 6:1 over protandry (male-to-female). We found 12 hermaphroditic species that can live in freshwater. However, seven of these species are from four primarily marine families while there are only five species from two mostly freshwater families. Protogynous and bi-directional sex changers have a tighter association with reef-associated tropical and subtropical habitats when compared to protandrous species, which tend to be more plastic in terms of distribution requirements. Finally, simultaneous hermaphrodite species live both in the deep sea and shallow waters in similar proportions. This study can be the basis for further research in specific groups for different purposes, including ecological and evolutionary issues as well as conservation and management of exploited species. Understanding the environmental correlates can help to forecast changes in the distribution or phenology of hermaphrodites in a global change scenario.
An Odd Coupling: Nietzsche and W.E.B. Du Bois on 21st Century Philosophy of Education
Authors: Verharen Charles C. 
Published: October 2021

AbstractThis essay contrasts Nietzsche’s remarks on elite education with W.E.B. Du Bois’ demand for democratized education. The essay takes their remarks as springboards for a twenty-first century philosophy of education rather than an historical account of their philosophies. Both thinkers cultivated Kant and Hegel’s dream that the spirit of freedom guided by reason would unite all the world’s peoples. Both held that education was key to realizing the dream. Their judgments about qualifying for education separated them. Nietzsche insisted that only the elite should receive the fullest measure of education. Du Bois believed that in the future virtually every human being would receive a university-level education. The essay’s principal point is to show how contemporary technology can make Du Bois’ dream a reality. An African philosopher’s working model demonstrates a path to universal university education.
Sensitivity of two SARS-CoV-2 variants with spike protein mutations to neutralising antibodies
Authors: Müller Katharina , Girl Philipp , Giebl Andreas , Gruetzner Stefanie , Antwerpen Markus , Khatamzas Elham , Wölfel Roman , von Buttlar Heiner 
Published: October 2021

AbstractSARS-CoV-2 infections elicit a humoral immune response capable of neutralising the virus. However, multiple variants have emerged with mutations in the spike protein amongst others, the key target of neutralising antibodies. We evaluated the neutralising efficacy of 89 serum samples from patients, infected with SARS-CoV-2 in the beginning of 2020, against two virus variants isolated from acutely infected patients and harbouring spike protein mutations. One isolate was assigned to lineage B.1.351 (MUC-IMB-B.1.351) whilst the other (MUC-484) was isolated from an immunocompromised patient, sharing some but not all mutations with B.1.351 and representing a transitional variant. Both variants showed a significant reduction in neutralisation sensitivity compared to wild-type SARS-CoV-2 with MUC-IMB-B.1.351 being almost completely resistant to neutralisation. The observed reduction in neutralising activity of wild-type-specific antibodies against both variants suggests that individual mutations in the spike protein are sufficient to confer a potent escape from the humoral immune response. In addition, the effect of escape mutations seems to accumulate, so that more heavily mutated variants show a greater loss of sensitivity to neutralisation up to complete insensitivity as observed for MUC-IMB-B.1.351. From a clinical point of view, this might affect the efficacy of (monoclonal) antibody treatment of patients with prolonged infections as well as patients infected with variants other than the donor. At the same, this could also negatively influence the efficacy of current vaccines (as they are based on wild-type spike protein) emphasising the need to thoroughly surveil the emergence and distribution of variants and adapt vaccines and therapeutics accordingly.
Head-to-head comparison of FNA cytology vs. calcitonin measurement in FNA washout fluids (FNA-CT) to diagnose medullary thyroid carcinoma. A systematic review and meta-analysis
Authors: Trimboli Pierpaolo , Giannelli Jacopo , Marques Bernardo , Piccardo Arnoldo , Crescenzi Anna , Deandrea Maurilio 
Published: October 2021

Abstract
Purpose
The sensitivity of cytology after fine needle aspiration (FNA-cytology) in detecting medullary thyroid carcinoma (MTC) is low. To overcome this problem, measuring calcitonin (CT) in washout fluid of FNA (FNA-CT) has been largely diffused and showed good performance. However, no evidence-based study exists comparing systematically the sensitivity of FNA-cytology and FNA-CT. This study aimed to systematically review the literature and collect data allowing a head-to-head comparison meta-analysis between FNA-cytology and FNA-CT in detecting MTC lesions.

Methods
The online databases of PubMed/MEDLINE and Scopus were searched until June 2021. Original articles reporting the use of both FNA-cytology and FNA-CT in the same series of histologically proven MTC lesions were included They were extracted general features of each study, number of MTC lesions (nodule and neck lymph nodes), and true positive and false negatives of both FNA-cytology and FNA-CT.

Results
Six studies were included. The sensitivity of FNA-cytology varied from 20% to 86% with a pooled value of 54% (95% CI 35–73%) and significant heterogeneity. The sensitivity of FNA-CT was higher than 95% in almost all studies with a pooled value of 98% (95% CI 96–100%) without heterogeneity. The sensitivity of FNA-CT was significantly higher than that of FNA-cytology.

Conclusions
FNA-CT is significantly more sensitive than FNA-cytology in detecting MTC. Accordingly, FNA-CT represents the standard method to use in patients with suspicious MTC lesions, combined with cytology.