bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantitative investigation of dose accumulation errors from intra-fraction motion in MRgRT for prostate cancer
Authors: Bosma L S , Zachiu C , Ries M , Denis de Senneville B , Raaymakers B W 
Published: January 2021

Abstract
Accurate spatial dose delivery in radiotherapy is frequently complicated due to changes in the patient’s internal anatomy during and in-between therapy segments. The recent introduction of hybrid MRI radiotherapy systems allows unequaled soft-tissue visualization during radiation delivery and can be used for dose reconstruction to quantify the impact of motion. To this end, knowledge of anatomical deformations obtained from continuous monitoring during treatment has to be combined with information on the spatio-temporal dose delivery to perform motion-compensated dose accumulation (MCDA). Here, the influence of the choice of deformable image registration algorithm, dose warping strategy, and magnetic resonance image resolution and signal-to-noise-ratio on the resulting MCDA is investigated. For a quantitative investigation, four 4D MRI-datasets representing typical patient observed motion patterns are generated using finite element modeling and serve as a gold standard. Energy delivery is simulated intra-fractionally in the deformed image space and, subsequently, MCDA-processed. Finally, the results are substantiated by comparing MCDA strategies on clinically acquired patient data. It is shown that MCDA is needed for correct quantitative dose reconstruction. For prostate treatments, using the energy per mass transfer dose warping strategy has the largest influence on decreasing dose estimation errors.
An SECE array of piezoelectric energy harvesting
Authors: Wu P H , Lin J T , Lo Y C , Shu Y C 
Published: January 2021

Abstract
The paper studies the electrical response of an array of piezoelectric oscillators attached to the synchronized electric charge extraction (SECE) interface circuit. The analytic estimate of output power is derived and presented through the matrix formulation of generalized Ohm’s law (charging on capacitance) for the case of parallel (series) connection of energy harvesters. These formulations mainly depend on the proposed equivalent load impedances which are independent of external resistive loads. It therefore offers an advantage of enabling harvested power independent of DC output voltage and making the harvester array desirable for broadband energy scavenging. The proposed framework is subsequently validated both numerically and experimentally. The results show that the power output and bandwidth of an SECE-based array are superior to that based on the standard energy harvesting circuit. Further, it is found that the behavior of an SECE array electrically arranged in parallel connection is different from that connected in series. The former demonstrates the output power higher than the latter, while the latter exhibits roughly uniform peak power in frequency response. However, the experiment indicates the unexpected power drop deviated significantly from the prediction in the array of harvesters connected in series. Such a discrepancy is explained as a result of comparatively serious leakage current in the reverse-biased diodes.
Non-classicalities exhibited by the superposition of Schrödinger’s cat state with the vacuum of the optical field
Authors: Mishra Karunesh Kumar , Yadav Dhiraj , Shukla Gaurav , Mishra Devendra Kumar 
Published: January 2021

Abstract
Superposition of two coherent states, the Schrodinger’s cat state, can exhibit different nonclassical properties having foundational applications in quantum information processing. We consider the ‘superposition of Schrodinger’s cat state with the vacuum state (SCVS)’ of the optical field. We discuss different witness of nonclassicality properties such as lower- and higher-order squeezing (viz., squeezing, Hong & Mandel’s fourth-order squeezing, amplitude-squared squeezing) and sub-Poissonian photon statistics. Further, we discuss the negativity of the Wigner function of SCVS indicating the nonclassicality of the state under investigation. We find that the vacuum state contribution in SCVS exhibits different nonclassicalities under some conditions stronger where the nonclassicalities exhibited by the state without vacuum state contribution are weaker.
A Small Actively Controlled High-resolution Spectrograph Based on Off-the-shelf Components
Authors: Jones H. R. A. , Martin W. E. , Anglada-Escudé G. , Errmann R. , Campbell D. A. , Baker C. , Boonsri C. , Choochalerm P. 
Published: January 2021

Abstract
We present the design and testing of a prototype in-plane echelle spectrograph based on an actively controlled fiber-fed double-pass design. This system aims to be small and efficient with the minimum number of optical surfaces—currently a collimator/camera lens, cross-dispersing prism, grating and a reflector to send light to the detector. It is built from catalog optical components and has dimensions of approximately 20 × 30 cm. It works in the optical regime with a resolution of >70,000. The spectrograph is fed by a bifurcated fiber with one fiber to a telescope and the other used to provide simultaneous Thorium Argon light illumination for wavelength calibration. The positions of the arc lines on the detector are processed in real time and commercial auto-guiding software is used to treat the positions of the arc lines as guide stars. The guiding software sends any required adjustments to mechanical piezo-electric actuators which move the mirror sending light to the camera removing any drift in the position of the arc lines. The current configuration using an sCMOS detector provides a precision of 3.5 milli-pixels equivalent to 4 m s−1 in a standard laboratory environment.
Probing the Properties of Gaia-CRF2 Quasars at the Faintest Magnitudes
Authors: Liao Shilong , Qi Zhaoxiang , Cao Zihuang , Tang Zhenghong 
Published: January 2021

Abstract
Gaia data release 2 (DR2) provides the best non-rotating optical frame aligned with the radio frame (ICRF) thanks to the inclusion of about half-million quasars in the five-parameter astrometric solution. We cross-match with Gaia DR2 the quasars from Large Quasar Astrometric Catalogue, Sloan Digital Sky Survey and LAMOST, obtaining 208,743 new sources (denominated as KQCG), and most of them are fainter than G = 19. Given their crucial diagnostic role for characterizing the properties of the celestial reference frame, we aim to probe more accurately the properties of the reference frame at the faintest magnitudes. Combining them with the quasars already identified in DR2, we estimate the moving mean of parallaxes and proper motions. The features of the proper motion are analyzed by means of vectorial spherical harmonics; the scalar field of parallaxes is expanded into spherical harmonics to investigate their spatial correlation, which reveals an angular scale of systematics of ≈18° with a rms amplitude of 13 μas. The global moving mean of the parallaxes and proper motions are calculated. The amplitude of proper motion bias can be up to ∼10 μas yr−1 in some sky regions for both components, and these biases seem to be related to the patterns of the scanning law. The reference frame exhibits a (−6, −5, −5) ± 1 μas yr−1 spin in the northern hemisphere and a spin of (0, +1, +3) ± 1 μas yr−1 in the southern one, which may be caused by the star contamination. The quadrupolar anisotropy of the proper motion filed is analyzed, where a significant quadrupolar signal (the largest component’s amplitude is up to −15 μas yr−1) is found.
Thermodynamics of warped anti-de Sitter black holes under scattering of scalar field *
Authors: Gwak Bogeun 
Published: January 2021

Abstract
We investigate the thermodynamics and stability of the horizons in warped anti-de Sitter black holes of the new massive gravity under the scattering of a massive scalar field. Under scattering, conserved quantities can be transferred from the scalar field to the black hole, thereby changing the state of the black hole. We determine that the changes in the black hole are well coincident with the laws of thermodynamics. In particular, the Hawking temperature of the black hole cannot be zero in the process as per the third law of thermodynamics. Furthermore, the black hole cannot be overspun beyond the extremal condition under the scattering of any mode of the scalar field.
Refining the cold atom pressure standard
Authors: Shen Pinrui , Madison Kirk W , Booth James L 
Published: January 2021

Abstract
In our previous work (Shen et al 2020 Metrologia
57 025015; Booth et al 2019 New J. Phys.
21 102001), we have reported the first primary quantum pressure standard based on the loss rate of cold rubidium atoms from a magnetic trap. We have shown that this standard is self-calibrating. That is, the single parameter required to quantify the pressure or particle flux impinging on the sensor atoms,

σ

t
o
t

v

, can be determined experimentally. In this paper, we refine our procedure to extract the trap loss rate coefficient by expressing the measured trap loss rate of the rubidium atoms as a convolution of the universal loss rate expression from Shen et al (2020 Metrologia
57 025015) and Booth et al (2019 New J. Phys.
21 102001) with the energy distribution of the rubidium atoms in the trap. We report improved

σ

t
o
t

v

values for 87Rb–X (X = He, Ar, Xe, H2, N2, and CO2) collision pairs. All are systematically higher than our previously reported values, although the differences are less than 2%. The calibration factor of an ionization gauge for nitrogen obtained using the cold atom standard, i
g = 0.950 (19), agrees with the value obtained by NIST, i
g = 0.940 (26) calibrated against their orifice flow standard.
Surface blistering and deuterium retention behaviors in pure and ZrC-doped tungsten exposed to deuterium plasma
Authors: Zhang Xue-Xi , Qiao Li , Zhang Hong , Li Yu-Hong , Wang Peng , Liu Chang-Song 
Published: January 2021

Abstract
Surface blistering and deuterium (D) retention behaviors in pure tungsten (W) and 0.5 wt% ZrC-doped W alloy (WZC) exposed to D plasma have been investigated as a function of incident D fluence up to 2.6 × 1025 D m−2. Surface observations show that large-sized blisters (∼8–10 μm) and a few small blisters (<2 μm) are formed on the W samples. For WZC, the surface of the samples is covered by a high density of small blisters (<1 μm), and no blister larger than 2 μm is found. Cross section views show that the large-sized blisters originate from subsurface grain boundaries, and the small blisters originate from intra-granular cavities at depths much closer to the surface. The intra-granular blisters are preferentially formed on the grains with a normal direction close to [111] for both types of sample. The inter-granular blisters formed in pure W are significantly suppressed in WZC, and the fluence threshold for blister formation in WZC is lower than that in W. The D depth distributions indicate that the implanted D is mainly retained in the near-surface region of WZC and W. Besides, a higher and broader D peak is observed at a depth of between 0.1–0.25 μm in WZC, but the intensity and width of the D peak is lower and thinner in W. The desorption spectra of WZC shift to the lower temperature side as compared to W, and the total retained D amount in WZC and W is comparable in the fluence range of 2.8 × 1024–2.6 × 1025 D m−2.
Global water scarcity including surface water quality and expansions of clean water technologies
Authors: van Vliet Michelle T H , Jones Edward R , Flörke Martina , Franssen Wietse H P , Hanasaki Naota , Wada Yoshihide , Yearsley John R 
Published: January 2021

AbstractWater scarcity threatens people in various regions, and has predominantly been studied from a water quantity perspective only. Here we show that global water scarcity is driven by both water quantity and water quality issues, and quantify expansions in clean water technologies (i.e. desalination and treated wastewater reuse) to ‘reduce the number of people suffering from water scarcity’ as urgently required by UN’s Sustainable Development Goal 6. Including water quality (i.e. water temperature, salinity, organic pollution and nutrients) contributes to an increase in percentage of world’s population currently suffering from severe water scarcity from an annual average of 30% (22%–35% monthly range; water quantity only) to 40% (31%–46%; both water quantity and quality). Water quality impacts are in particular high in severe water scarcity regions, such as in eastern China and India. In these regions, excessive sectoral water withdrawals do not only contribute to water scarcity from a water quantity perspective, but polluted return flows degrade water quality, exacerbating water scarcity. We show that expanding desalination (from 2.9 to 13.6 billion m3month−1) and treated wastewater uses (from 1.6 to 4.0 billion m3month−1) can strongly reduce water scarcity levels and the number of people affected, especially in Asia, although the side effects (e.g. brine, energy demand, economic costs) must be considered. The presented results have potential for follow-up integrated analyses accounting for technical and economic constraints of expanding desalination and treated wastewater reuse across the world.
Deep decarbonization pathways in the building sector: China’s NDC and the Paris agreement
Authors: Xing Rui , Hanaoka Tatsuya , Masui Toshihiko 
Published: January 2021

Abstract
China’s economic growth has been largely relying on the consumption of coal. The country has realized that its economic development has to be free from dependence on fossil fuels. On 30 June 2015, China submitted its ‘Nationally Determined Contribution (NDC)’ in preparation for the Conference of Parties 21 (COP21). One of the important actions in China’s NDC is to lower carbon dioxide (CO2) emissions per unit of GDP by 60% to 65% from 2005 levels by 2030. This study examines the efforts from China’s building sector (i.e. urban residential, rural residential and service) in achieving the CO2 reduction target stated in China’s NDC. Furthermore, this study also explores the post-NDC era and looks into the opportunities towards deep decarbonization in the building sector by mid-century for contributing to the Paris agreement. The study covers 31 provincial regions of mainland China anddisparities of climate and socioeconomic indicators across regions are fully considered. We use a bottom-up cost optimization model called AIM/Enduse to evaluate the CO2 reduction potential brought by efficient technologies in China’s building sector. Five scenarios are designed to illustrate the emission pathways through 2050. The results show that, when energy constraint and emission target is introduced in mitigation scenarios, new generation biomass contribute a lot to emission reduction. Reduction potential in the nearly zero emission scenario is mainly from the urban residential sector, and to achieve deep decarbonization by 2050, it is important to bring a significant reduction of per-capita energy consumption in addition to ci improvement both in urban and rural households. Co-benefit analysis suggests that air pollutants can also be significantly reduced by deep decarbonization policies.
Local invariants of braiding quantum gates—associated link polynomials and entangling power
Authors: Padmanabhan Pramod , Sugino Fumihiko , Trancanelli Diego 
Published: January 2021

Abstract
For a generic n-qubit system, local invariants under the action of

S
L

(

2
,
C

)

⊗
n

characterize non-local properties of entanglement. In general, such properties are not immediately apparent and hard to construct. Here we consider two-qubit Yang–Baxter operators and show that their eigenvalues completely determine the non-local properties of the system. Moreover, we apply the Turaev procedure to these operators and obtain their associated link/knot polynomials. We also compute their entangling power and compare it with that of a generic two-qubit operator.
Biofabrication of spheroids fusion-based tumor models: computational simulation of glucose effects
Authors: Bustamante David J , Basile Elijah J , Hildreth Brady M , Browning Nathan W , Jensen S Alexander , Moldovan Leni , Petrache Horia I , Moldovan Nicanor I 
Published: January 2021

Abstract

In vitro tumor models consisting of cell spheroids are increasingly used for mechanistic studies and pharmacological testing. However, unless vascularized, the availability of nutrients such as glucose to deeper layers of multicellular aggregates is limited. In addition, recent developments in cells-only biofabrication (e.g. ‘scaffold-free bioprinting’), allow the creation of more complex spheroid-based structures, further exposing the cells to nutrient deprivation within these constructs. To explore the impact of glucose availability on such tumor-like structures, we used the CompuCell3D platform for modeling of tumor spheroids. By monitoring the types of cells, fusing pairs geometry and the distance between spheroids centers of mass, we made novel heuristic observations on how binary- and multi-spheroid fusions are impacted by glucose availability. At limiting glucose concentrations mimicking hypoglycemia we noted an abrupt collapse of the tumor spheroids, unexpectedly amplified by the contact with normal cell spheroids. At higher glucose concentrations, we found an increased intermixing of cancerous cells, strong anti-phase oscillations between proliferating and quiescent tumor cells and a structural instability of fusing tumor spheroids, leading to their re-fragmentation. In a model of tumor microenvironment composed of normal cell spheroids fusing around a tumoral one, the competition for glucose lead to either the tumor’s disappearance, to a steady state, or to its expansion. Moreover, the invasion of this microenvironment by individual tumor cells was also strongly depended on the available glucose. In conclusion, we demonstrate the value of computational simulations for anticipating the properties of biofabricated tumor models, and in generating testable hypotheses regarding the relationship between cancer, nutrition and diabetes.
Recent advancements towards large-scale flow diagnostics by robotic PIV
Authors: Scarano Fulvio , Jux Constantin , Sciacchitano Andrea 
Published: January 2021

Abstract
The present work reviews the recent developments in the domain of particle image velocimetry (PIV) with attention to its use for large-scale problems of interest for industrial aerodynamics. The article introduces the fundamental principles of flow seeding for large-scale experiments based on the helium-filled soap bubble (HFSB) technique. The measurement of flow tracers in a three-dimensional domain is presented, which is based on Lagrangian tracking methods. Furthermore, the concept of co-axial volumetric velocimetry is introduced and its combination with robotic arm manipulation is shown. The work presents two main examples of applications to aerodynamic problems: the first is the flow field around a propeller aircraft at wind tunnel free-stream velocity up to 50 m s−1, which to date is considered the boundary of large-scale PIV application with HFSB. The second example is the complex three-dimensional flow field around a cyclist at full scale. The work summarizes developments obtained in the last 3 years of research, demonstrating that the domain of PIV techniques is still undergoing vivid developments.
Positron impact excitation of lowest autoionizing state of potassium atom using distorted wave method with absorption and polarization potentials
Authors: William Noah Nzeki , Jobunga Eric Ouma , Singh Chandra Shekhar 
Published: January 2021

Abstract
Differential and integral cross-sections, as well as the alignment and lambda parameters for positron impact excitation of the lowest autoionizing state of potassium atom, have been calculated using a non-relativistic distorted wave method in the energy range of 18.9–1500 eV. The distortion potential in the initial and final channel state comprises a linear combination of static potential plus polarization and absorption potentials. The approximate Roothan-Hartree–Fock (RHF) wavefunctions Multi zeta wave functions given by Clementi and Roetti have been used. The inclusion of polarization and absorption potentials has improved integral cross-section and alignment parameter results. The integral cross sections have shown the near-threshold resonance structure revealed in electron impact excitation experimental results. Differential cross-section and lambda parameter results have been calculated and presented for future comparison since there are no other results available in the literature for positron impact excitation.
15% reduction in AC loss of a 3-phase 1 MVA HTS transformer by exploiting asymmetric conductor critical current
Authors: Jiang Zhenan , Song Wenjuan , Pei Xiaoze , Fang Jin , Badcock Rodney A , Wimbush Stuart C 
Published: January 2021

Abstract
An asymmetric dependence of the critical current on the direction of an applied magnetic field in HTS coated conductors has a non-trivial influence on the AC loss of coil windings. We report the modelled influence of real conductor critical current asymmetry on the AC loss characteristics of a 1 MVA HTS transformer design previously demonstrated by the Robinson Research Institute as well as a stand-alone coil having the same geometrical and electrical parameters as the low voltage (high current) winding of the transformer. We compare two commercial HTS conductors with distinctive differences in their critical current asymmetry and show a maximum variation of 15% and 29% in the calculated AC loss of the transformer and the stand-alone coil winding, respectively, when the conductor orientation is varied in the top and bottom halves of the windings. AC loss simulation giving consideration to asymmetric conductor critical current before winding the transformer could lead to substantial AC loss reduction even using the same amount of conductor and the same transformer design.
Home Blood Pressure Monitoring: Current Status and New Developments
Authors: Kario Kazuomi 
Published: January 2021

Abstract
Home blood pressure monitoring (HBPM) is a reliable, convenient, and less costly alternative to ambulatory blood pressure monitoring (ABPM) for the diagnosis and management of hypertension. Recognition and use of HBPM have dramatically increased over the last 20 years and current guidelines make strong recommendations for the use of both HBPM and ABPM in patients with hypertension. The accuracy and reliability of home blood pressure (BP) measurements require use of a validated device and standardized procedures, and good patient information and training. Key HBPM parameters include morning BP, evening BP, and the morning–evening difference. In addition, newer semi-automatic HBPM devices can also measure nighttime BP at fixed intervals during sleep. Advances in technology mean that HBPM devices could provide additional relevant data (e.g., environmental conditions) or determine BP in response to a specific trigger (e.g., hypoxia, increased heart rate). The value of HBPM is highlighted by a growing body of evidence showing that home BP is an important predictor of target organ damage, and cardiovascular disease (CVD)- and stroke-related morbidity and mortality, and provides better prognostic information than office BP. In addition, use of HBPM to monitor antihypertensive therapy can help to optimize reductions in BP, improve BP control, and reduce target organ damage and cardiovascular risk. Overall, HBPM should play a central role in the management of patients with hypertension, with the goal of identifying increased risk and predicting the onset of CVD events, allowing proactive interventions to reduce risk and eliminate adverse outcomes.