bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autopreening behaviour may convey information about internal social state in Arabian babbler (Turdoides squamiceps) allopreening dyads
Authors: Fulmer Andrew Goldklank , Hauber Mark E. 
Published: February 2021

Abstract
When individuals groom or preen one another (allopreening), vulnerability and physical access allow for information about hierarchy and bonds to be exchanged, in addition to basic health benefits. During these interactions, individuals may also self-direct grooming/preening (autopreening). We investigate autopreening in a cooperatively breeding passerine bird, the Arabian babbler (Turdoides squamiceps) in the specific context of allopreening interactions. Auto- and allogrooming (the mammalian analogue behaviours) may occur in sequence together, with some species socially facilitating allogrooming by autogrooming. We here consider the possibility of similar associations between autopreening and allopreening. Using a two-year database of 35 individuals in 8 social groups, we assessed the social factors that predict the occurrence of autopreening and its timing in the context of allopreening dyad formation. We ask if there is a social dimension to this behaviour, and specifically find evidence that it may represent displacement and/or subordinate behaviour. The relative age of individuals in preening dyads and the behaviour of recipients prior to social approach significantly predicted the behaviour of recipients as the preening dyad was formed: recipients were less likely to autopreen before approaching older actors to begin an allopreening bout. When recipients autopreened, actors were more likely to make the approach. Recipients that did not autopreen or otherwise conspicuously display were significantly more likely to approach the actor without first autopreening. We suggest that autopreening in these bouts is a socially modulated behaviour representative of uncertainty and/or subordination.
Heritability and characteristics of resin ducts in Pinus oocarpa stems in Michoacán, Mexico
Authors: Fabián-Plesníková Irenka , Sáenz-Romero Cuauhtémoc , Cruz-De-León José , Martínez-Trujillo Miguel , Sánchez-Vargas Nahum M. , Terrazas Teresa 
Published: February 2021

Abstract
Despite the extensive distribution and use of Pinus oocarpa in Mexico, knowledge on the range of genetic variation and magnitude of quantitative parameters of the defensive structures of the species is rare. Our study attempts to fill this gap by providing a comprehensive assessment of resin duct traits in mother trees and their offsprings in an open-pollinated trial of P. oocarpa. Resin ducts are fundamental structures of the defense mechanisms of the coniferous trees. They vary depending on the age of the tree, the genotype, the species, and may be influenced by environmental factors. We investigated intraspecific variation among families of the resin duct system in secondary vascular tissues (wood and inner bark) of P. oocarpa trees. Our study attempts to explore the variance and the possible genetic control of these defensive structures. We hypothesized that the resin duct features analyzed would vary with the tree’s genetic make-up. We analyzed samples from two groups of trees. First, from mature mother trees selected as superior in resin yield. Second, from their six-year-old off-springs established in a progeny trial. Axial and radial ducts showed differences in their size and quantity, between wood and bark and between ages. The axial duct density showed differences among families, and the heritability estimates were moderate. In P. oocarpa trees selected as phenotypically superior in resin yield, the size of its constitutive resin ducts is a less variable trait, and the differences in axial duct density can be attributed to genetic factors.
Subseasonal Predictability of Arctic Ocean Sea Ice Conditions: Bering Strait and Ekman-Driven Ocean Heat Transport
Authors: Lenetsky Jed E. , Tremblay Bruno , Brunette Charles , Meneghello Gianluca 
Published: February 2021

AbstractWe use ocean observations and reanalyses to investigate the subseasonal predictability of summer and fall sea ice area (SIA) in the western Arctic Ocean associated with lateral ocean heat transport (OHT) through Bering Strait and vertical OHT along the Alaskan coastline from Ekman divergence and upwelling. Results show predictive skill of spring Bering Strait OHT anomalies in the Chukchi Sea and eastern East Siberian Sea for June and July SIA, followed by a sharp drop in predictive skill in August, September, and October and a resurgence of the correlation in November during freeze-up. Fall upwelling of Pacific Water along the Alaskan coastline—a mechanism that was proposed as a preconditioner for lower sea ice concentration (SIC) in the Beaufort Sea the following summer—shows minimal predictive strength on both local and regional scales for any months of the melt season. A statistical hindcast based on May Bering Strait OHT anomalies explains 77% of July Chukchi Sea SIA variance. Using OHT as a predictor of SIA anomalies in the Chukchi Sea improves hindcasts from the simple linear trend by 35% and predictions from spring sea ice thickness anomalies by 24%. This work highlights the importance of ocean heat anomalies for melt season sea ice prediction and provides observational evidence of subseasonal changes in forecast skill observed in model-based forecasts of the Chukchi Sea.
A Real-Time Algorithm to Identify Convective Precipitation Adjacent to or within the Bright Band in the Radar Scan Domain
Authors: Zhang Zhe , Qi Youcun , Li Donghuan , Zhu Ziwei , Yang Meilin , Wang Nan , Yang Yin , Hu Qiyuan 
Published: February 2021

AbstractHydrological hazards usually occur after heavy precipitation, especially during strong convection. Therefore, accurately identifying convective precipitation is very helpful for hydrological warning and forecasting. However, separating the convective, bright band (BB), and stratiform precipitation is found to be challenging when the convection is adjacent to or within the BB region. A new convection/BB/stratiform precipitation segregation algorithm is proposed in this study to resolve this challenging issue. This algorithm is applicable for a single radar volume scan data in native (polar) coordinates and consists of four processes: 1) check the freezing (0°C) level to roughly assess whether convection is occurring or not; 2) identify the convective cores through analyzing composite reflectivity (maximum reflectivity for a given range gate among all the sweeps), vertically integrated liquid water (VIL), VIL horizontal gradient, and reflectivity at the levels of 0°, −10°, and above −10°C; 3) delineate the whole convective region through the seeded region growing method by taking account of the microphysical differences between the BB and convective regions; and 4) delineate BB features in the stratiform region. The proposed algorithm utilizes the physical characteristics of different precipitation types for precisely segregating the convective, BB, and stratiform precipitation. This algorithm has been tested with radar data of different precipitation events and evaluated with three months of rain gauge data. The results show that the proposed algorithm performs consistently well for challenging precipitation events with the convection adjacent to or within a strong BB. Furthermore, the proposed algorithm could be used to improve the vertical profile of reflectivity (VPR) correction and reduce the overestimation of rainfall in the BB precipitation region.
A Cost-Benefit Analysis of an Overseas Volunteer Mission to the Local Healthcare System
Authors: Gachabayov Mahir , Latifi Lulejeta A. , Rivera Renato , Baluyot Fancy S. , Latifi Rifat 
Published: February 2021

Background The aim of this study was to comparatively evaluate the sustainability and cost-benefit of the Operation Giving Back Bohol surgical volunteerism mission (SVM) carried out in Bohol Province, Philippines, over twelve consecutive missions. Methods This was a cost-benefit analysis of prospectively collected financial data from twelve consecutive surgical volunteerism missions held between 2006 and 2018. The overall cost of an SVM and cost per patient were the endpoints of interest. Disability-adjusted life years (DALYs) and costs thereof were calculated for each patient undergoing surgery in the twelve SVMs. Results A mean of 112 ± 22 patients were included per year of the SVM. A statistically significant increasing trend in the overall cost of SVMs over time was found ( R2 = .469; P = .014). A nonsignificant decreasing trend in the cost per patient over time was found ( R2 = .007; P = .795). A total of 8811.71 DALYs were averted in the twelve SVMs. DALYs averted per year ranged between 474.02 (2009) and 969.16 (2012). Cost per a DALY averted ranged between $466.9 (2006) and $865.6 (2009). Comparison of the latter with GDP per capita showed that this SVM was “very cost-effective.” Conclusion The SVM contributes substantially to the health care system both clinically and financially. A total of 8812 DALYs were averted in these twelve SVMs. Costs per a DALY averted did not significantly change over the mission years. Increasing the number of patients served has increased the total cost of the mission with no impact on the cost per patient.
Incidental Findings on Whole-body Computed Tomography in Major Trauma Patients: Who and What?
Authors: Liu Ping-Yuan , Kuo Ling-Wei , Liao Chien-Hung , Hsieh Chi-Hsun , Bajani Francesco , Fu Chih-Yuan 
Published: February 2021

Purpose Whole-body computed tomography (WBCT) scans are frequently used for trauma patients, and sometimes, nontraumatic findings are observed. We aimed to investigate the characteristics of patients with nontraumatic findings on WBCT. Methods From 2013 to 2016, adult trauma patients who underwent WBCT were enrolled. The proportions of nontraumatic findings in different anatomical regions were studied. Nontraumatic findings were classified and evaluated as clinically important findings and findings that needed no further follow-up or treatment. The characteristics of the patients with nontraumatic findings were analyzed and compared with those of patients without nontraumatic findings. Results Two hundred seventeen patients were enrolled in this study during the 3-year study period, and 89 (41.0%) patients had nontraumatic findings. Nontraumatic findings were found more frequently in the abdomen (69.2%) than in the head/neck (17.3%) and chest regions (13.5%). In total, 31.3% of the findings needed further follow-up or treatment. Patients with nontraumatic findings that needed further management were significantly older than those without nontraumatic findings (57.3 vs. 38.9; P < .001), particularly those with abdominal nontraumatic findings (57.9 vs. 41.3; P < .001). A significantly higher proportion of women were observed in the group with head/neck nontraumatic findings that needed further management than in the group without nontraumatic findings (56.3% vs 24.9%; P = .015). Conclusions Whole-body computed tomography could provide alternative benefits for nontraumatic findings. Whole-body computed tomography images should be read carefully for nontraumatic findings, particularly for elderly patients or the head/neck region of female patients. A comprehensive program for the follow-up of nontraumatic findings is needed.
Governance capacity and regulatory enforcement: street-level organizations in Beijing’s food safety reform
Authors: Yee Wai-Hang , Liu Peng 
Published: February 2021

How street-level organizations enforce regulations carries important governance implications. Through reviewing the regulatory enforcement literature and categorizing it into three broad governance modes, this article discusses the individual and organizational capacity prerequisites for street-level organizations to enact the corresponding government–society relationship and improve governance outcomes. Through analyzing enforcement challenges faced by street-level officers in Beijing’s recent food safety reform, the article also identifies the essential capacities for street-level organizations to regulate under a legal-hierarchical governance mode. The article hopes to inspire further research to uncover specific governance capacity requirements for other administrative organizations under different governance modes. Points for practitioners Apart from policy effectiveness, government regulators should also sometimes pay attention to their impacts on governance. Despite frontline regulators’ discretion, street-level organizations may improve governance outcomes by devising and implementing regulatory enforcement programs and strategies in line with the governance mode the government is engaged in as what they do enacts the specific government–society relationship in the governing process. Administrators in charge of street-level organizations may benefit from cultivating capacities essential to actualizing the respective governance mode. Absence of these capacities is likely to undermine governance effectiveness.
Predicting Risk of Recurrent Patellofemoral Instability With Measurements of Extensor Mechanism Containment
Authors: Weltsch Daniel , Chan Calvin T. , Mistovich R. Justin , Urwin John W. , Gajewski Christopher R. , Fabricant Peter D. , Lawrence J. Todd R. 
Published: February 2021

Background: Identifying risk factors for recurrent patellar dislocation after a primary dislocation may help guide initial treatment. Magnetic resonance imaging (MRI) measurements relating the alignment of the extensor mechanism to trochlear morphology have been shown to distinguish patients with dislocations from controls, but their usefulness in predicting the risk of a second dislocation is not known. Purpose: To identify the association of novel MRI measures of patellar containment with recurrent instability in pediatric patients presenting with a first-time patellar dislocation. Study Design: Cohort study (Prognosis); Level of evidence, 3. Methods: The study was conducted at a tertiary care children’s hospital (2005-2014) on patients (age, 8-19 years) with a first-time patellar dislocation. MRI measurements were made by 2 independent raters. Interobserver reliability was assessed for all measurements via an intraclass correlation coefficient (ICC). Only measurements with an ICC >0.8 were included. Univariable and multivariable logistic regression analyses were used to evaluate variables associated with recurrence. Results: A total of 165 patients with a median age of 14 years and a slight (57.6%) female predominance was identified. The median follow-up length of the whole cohort was 12.2 months (interquartile range, 1.6-37.1 months). Subsequent instability was documented in 98 patients (59.4%). MRI measurements with excellent correlation (ICC > 0.8) were the tibial tubercle to trochlear groove distance (TT-TG), the tangential axial width of the patella, the tangential axial trochlear width, the axial width of the patellar tendon beyond the lateral trochlear ridge (LTR), and the tibial tubercle to LTR distance. In univariate analysis, all mentioned MRI measurements had significant association with recurrent instability. However, after both backward and forward stepwise regression analyses, the tibial tubercle to LTR distance was the only independent predictor of recurrent instability ( P = .003 in both). Patients with a tibial tubercle to LTR distance value greater than –1 mm had a significantly higher rate of recurrent patellar dislocation (72%). Conclusion: Of numerous axial view MRI parameters, only the tibial tubercle to LTR distance demonstrated a statistically significant association with recurrent patellar instability upon multivariable logistic regression analysis during short-term follow-up of a pediatric population presenting with initial lateral patellar dislocation. Interobserver correlation of the tibial tubercle to LTR distance was good (ICC > 0.8) and similar to that of TT-TG.
“…[T]his is What We are Missing”: The Value of Communicating Infant Feeding Information Across Three Generations of African American Women
Authors: Woods Barr Alexis L. , Austin Deborah A. , Smith Jacquana L. , Schafer Ellen J. 
Published: February 2021

Background Breast/Chestfeeding remains a public health issue for African Americans, and increased rates would mitigate many health disparities, thus promoting health equity. Research Aims To explore the interplay of generational familial roles and meaning (or value) ascribed to communicating infant feeding information across three generations. Method This prospective, cross-sectional qualitative study used an asset-driven approach and was guided by Black Feminist Thought and Symbolic Interactionism. African American women ( N = 35; 15 family triads/dyads), residing in the southeastern United States were interviewed. Data were analyzed using thematic analysis. Results The older two generations described their role using assertive yet nurturing terms, while the younger generation carefully discussed the flexibility between their familial roles. Emergent themes described the meaning each generation attributed to communicating infant feeding information: “My Responsibility,” “Comforting,” “Bonding Experience,” “She Cared,” and “Gained Wisdom.” Conclusions Our findings have potential to contribute to achieving health equity in African American families. Future breast/chestfeeding promotion efforts may benefit from reframing the current approach to including protection language and not solely support language. Lactation professionals should further recognize and support strengths and resource-richness of intergenerational infant feeding communication within African American families using strength-based, empowerment-oriented, and ethnically sensitive approaches.
Benefits and harms of breast cancer mammography screening for women at average risk of breast cancer: A systematic review for the European Commission Initiative on Breast Cancer
Authors: Canelo-Aybar Carlos , Ferreira Diogenes S , Ballesteros Mónica , Posso Margarita , Montero Nadia , Solà Ivan , Saz-Parkinson Zuleika , Lerda Donata , Rossi Paolo G , Duffy Stephen W , Follmann Markus , Gräwingholt Axel , Alonso-Coello Pablo 
Published: February 2021

Objectives Mammography screening is generally accepted in women aged 50–69, but the balance between benefits and harms remains controversial in other age groups. This study systematically reviews these effects to inform the European Breast Cancer Guidelines. Methods We searched PubMed, EMBASE and Cochrane Library for randomised clinical trials (RCTs) or systematic reviews of observational studies in the absence of RCTs comparing invitation to mammography screening to no invitation in women at average breast cancer (BC) risk. We extracted data for mortality, BC stage, mastectomy rate, chemotherapy provision, overdiagnosis and false-positive-related adverse effects. We performed a pooled analysis of relative risks, applying an inverse-variance random-effects model for three age groups (<50, 50–69 and 70–74). GRADE (Grading of Recommendations Assessment, Development and Evaluation) was used to assess the certainty of evidence. Results We identified 10 RCTs including 616,641 women aged 38–75. Mammography reduced BC mortality in women aged 50–69 (relative risk (RR) 0.77, 95%CI (confidence interval) 0.66–0.90, high certainty) and 70–74 (RR 0.77, 95%CI 0.54–1.09, high certainty), with smaller reductions in under 50s (RR 0.88, 95%CI 0.76–1.02, moderate certainty). Mammography reduced stage IIA+ in women 50–69 (RR 0.80, 95%CI 0.64–1.00, very low certainty) but resulted in an overdiagnosis probability of 23% (95%CI 18–27%) and 17% (95%CI 15–20%) in under 50s and 50–69, respectively ( moderate certainty). Mammography was associated with 2.9% increased risk of invasive procedures with benign outcomes ( low certainty). Conclusions For women 50–69, high certainty evidence that mammography screening reduces BC mortality risk would support policymakers formulating strong recommendations. In other age groups, where the net balance of effects is less clear, conditional recommendations will be more likely, together with shared decision-making.
Neurofilament light chain in a phase 2 clinical trial of ibudilast in progressive multiple sclerosis
Authors: Fox Robert J , Raska Paola , Barro Christian , Karafa Matthew , Konig Victoria , Bermel Robert A , Chase Marianne , Coffey Christopher S , Goodman Andrew D , Klawiter Eric C , Naismith Robert T , Kuhle Jens 
Published: February 2021

Background: Sensitive and specific biomarkers for use in progressive multiple sclerosis (MS) have not been established. We investigate neurofilament light (NfL) as a treatment response biomarker in progressive MS. Objective: To evaluate whether ibudilast 100 mg/day alters serum and cerebrospinal fluid (CSF) levels of NfL in progressive MS. Methods: In a protocol-defined exploratory analysis from a 2-year, phase 2 clinical trial of ibudilast in progressive MS (NCT01982942), serum samples were collected from 239 subjects and a subset contributed CSF and assayed using single-molecule assay (SIMOA) immunoassay. A mixed model for repeated measurements yielded log(NfL) as the response variable. Results: The geometric mean baseline serum NfL was 31.9 and 28.8 pg/mL in placebo and ibudilast groups, respectively. The geometric mean baseline CSF NfL was 1150.8 and 1290.3 pg/mL in placebo and ibudilast groups, respectively. Serum and CSF NfL correlations were r = 0.52 and r = 0.78 at weeks 48 and 96, respectively. Over 96 weeks, there was no between-group difference in NfL in either serum ( p = 0.76) or CSF ( p = 0.46). After controlling for factors that may affect NfL, no effect of ibudilast on NfL in either serum or CSF was observed. Conclusion: Ibudilast treatment was not associated with a change in either serum or CSF NfL.
Aortic Remodeling After Custom-Made Candy-Plug for Distal False Lumen Occlusion in Aortic Dissection
Authors: Eleshra Ahmed , Rohlffs Fiona , Spanos Konstantinos , Panuccio Giuseppe , Heidemann Franziska , Tsilimparis Nikolaos , Kölbel Tilo 
Published: February 2021

Purpose: To report a single-center experience with the use of a custom-made Candy-Plug (CP) for distal false-lumen (FL) occlusion in subacute and chronic aortic dissection (AD). Materials and Methods: A retrospective single-center analysis was conducted on consecutive patients with subacute and chronic AD who were treated with a custom-made CP for distal FL occlusion using 3 design generations (CP I to CP III) from October 2013 to September 2019. Results: A custom-made CP was used in 57 patients. Of these, 34 patients (29 males, mean age 62±10 years) were treated with a CP I vs 23 patients (16 males, mean age 59±17 years) with CP II/III. Technical success was achieved in 57 (100%) patients. Clinical success was achieved in 54 (95%) patients; 33 (97%) in CP I group vs 21 (91%) patients in CP II/III group, p=0.116. The mean hospital stay was 10±8 days (9±5 days in CP I group vs 13±9 days in CP II/III, p=0.102). The 30-day computed tomography angiography (CTA) confirmed successful CP placement at the intended level in all patients within both groups. Early complete FL occlusion was achieved in 50 (88%) patients; 30 (88%) patients in CP I group vs 20 (87%) in CP II/III group, p=0.894. Follow up CTA was available in 44 (77%) patients. Of these; 30/34 (88%) patients in CP I group with mean follow-up 29±17 months) vs. 14/23 (61%) patients with mean follow-up 14±5 months in CP II/III group. Thoracic aortic remodeling was achieved in 34/44 (77%) patients; 25/30 (83%) patients in CP I group vs 9/14 (64%) patients in CP II/III group, p=0.197. The aneurysm size remained stable in 9/44 (20%) patients; 5/30 (17%) patients in CP I group vs 4/14 (29%) patients in CP II/III group, p=0.741. The thoracic aneurysm increased size was seen in 1/44 (2%) patient. This patient was in CPII/III group. Conclusion: CP technique using custom-made devices is technically feasible with a low mortality and morbidity, and a high rate of aortic remodeling. Both, the original design (CP I) and newer designs with a self-closing central sleeve (CP II and CP III) showed similar excellent outcomes.