bluuebunny/crossref_metadata_2025_split huggingface dataset:
Double-Janus linear sigma models and generalized reciprocity for Gauss sums
Authors: Ganor Ori J. , Sun Hao-Yu , Torres-Chicon Nesty R. 
Published: May 2021

Abstract
We study the supersymmetric partition function of a 2d linear σ-model whose target space is a torus with a complex structure that varies along one worldsheet direction and a Kähler modulus that varies along the other. This setup is inspired by the dimensional reduction of a Janus configuration of 4d $$ \mathcal{N} $$
N
= 4 U(1) Super-Yang-Mills theory compactified on a mapping torus (T2 fibered over S1) times a circle with an SL(2, ℤ) duality wall inserted on S1, but our setup has minimal supersymmetry. The partition function depends on two independent elements of SL(2, ℤ), one describing the duality twist, and the other describing the geometry of the mapping torus. It is topological and can be written as a multivariate quadratic Gauss sum. By calculating the partition function in two different ways, we obtain identities relating different quadratic Gauss sums, generalizing the Landsberg-Schaar relation. These identities are a subset of a collection of identities discovered by F. Deloup. Each identity contains a phase which is an eighth root of unity, and we show how it arises as a Berry phase in the supersymmetric Janus-like configuration. Supersymmetry requires the complex structure to vary along a semicircle in the upper half-plane, as shown by Gaiotto and Witten in a related context, and that semicircle plays an important role in reproducing the correct Berry phase.
Summing over geometries in string theory
Authors: Eberhardt Lorenz 
Published: May 2021

Abstract
We examine the question how string theory achieves a sum over bulk geometries with fixed asymptotic boundary conditions. We discuss this problem with the help of the tensionless string on $$ {\mathrm{\mathcal{M}}}_3\times {\mathrm{S}}^3\times {\mathbbm{T}}^4 $$

ℳ
3

×

S
3

×

T
4

(with one unit of NS-NS flux) that was recently understood to be dual to the symmetric orbifold SymN ($$ {\mathbbm{T}}^4 $$

T
4

). We strengthen the analysis of [1] and show that the perturbative string partition function around a fixed bulk background already includes a sum over semi-classical geometries and large stringy corrections can be interpreted as various semi-classical geometries. We argue in particular that the string partition function on a Euclidean wormhole geometry factorizes completely into factors associated to the two boundaries of spacetime. Central to this is the remarkable property of the moduli space integral of string theory to localize on covering spaces of the conformal boundary of ℳ3. We also emphasize the fact that string perturbation theory computes the grand canonical partition function of the family of theories ⊕N SymN ($$ {\mathbbm{T}}^4 $$

T
4

). The boundary partition function is naturally expressed as a sum over winding worldsheets, each of which we interpret as a ‘stringy geometry’. We argue that the semi-classical bulk geometry can be understood as a condensate of such stringy geometries. We also briefly discuss the effect of ensemble averaging over the Narain moduli space of $$ {\mathbbm{T}}^4 $$

T
4

and of deforming away from the orbifold by the marginal deformation.
A natural mechanism for approximate Higgs alignment in the 2HDM
Authors: Draper Patrick , Ekstedt Andreas , Haber Howard E. 
Published: May 2021

Abstract
The 2HDM possesses a neutral scalar interaction eigenstate whose tree-level properties coincide with the Standard Model (SM) Higgs boson. In light of the LHC Higgs data which suggests that the observed Higgs boson is SM-like, it follows that the mixing of the SM Higgs interaction eigenstate with the other neutral scalar interaction eigenstates of the 2HDM should be suppressed, corresponding to the so-called Higgs alignment limit. The exact Higgs alignment limit can arise naturally due to a global symmetry of the scalar potential. If this symmetry is softly broken, then the Higgs alignment limit becomes approximate (although still potentially consistent with the current LHC Higgs data). In this paper, we obtain the approximate Higgs alignment suggested by the LHC Higgs data as a consequence of a softly broken global symmetry of the Higgs Lagrangian. However, this can only be accomplished if the Yukawa sector of the theory is extended. We propose an extended 2HDM with vector-like top quark partners, where explicit mass terms in the top sector provide the source of the soft symmetry breaking of a generalized CP symmetry. In this way, we can realize approximate Higgs alignment without a significant fine-tuning of the model parameters. We then explore the implications of the current LHC bounds on vector-like top quark partners for the success of our proposed scenario.
Dispersive CFT sum rules
Authors: Caron-Huot Simon , Mazáč Dalimil , Rastelli Leonardo , Simmons-Duffin David 
Published: May 2021

Abstract
We give a unified treatment of dispersive sum rules for four-point correlators in conformal field theory. We call a sum rule “dispersive” if it has double zeros at all double-twist operators above a fixed twist gap. Dispersive sum rules have their conceptual origin in Lorentzian kinematics and absorptive physics (the notion of double discontinuity). They have been discussed using three seemingly different methods: analytic functionals dual to double-twist operators, dispersion relations in position space, and dispersion relations in Mellin space. We show that these three approaches can be mapped into one another and lead to completely equivalent sum rules. A central idea of our discussion is a fully nonperturbative expansion of the correlator as a sum over Polyakov-Regge blocks. Unlike the usual OPE sum, the Polyakov-Regge expansion utilizes the data of two separate channels, while having (term by term) good Regge behavior in the third channel. We construct sum rules which are non-negative above the double-twist gap; they have the physical interpretation of a subtracted version of “superconvergence” sum rules. We expect dispersive sum rules to be a very useful tool to study expansions around mean-field theory, and to constrain the low-energy description of holographic CFTs with a large gap. We give examples of the first kind of applications, notably we exhibit a candidate extremal functional for the spin-two gap problem.
All-order quartic couplings in highly symmetric D-brane-anti-D-brane systems
Authors: Hatefi Ehsan , Sundell Per 
Published: May 2021

Abstract
We compute six-point string amplitudes for the scattering of one closed string Ramond-Ramond state, two tachyons and two gauge fields in the worldvolume of D-brane-anti-D-brane systems in the Type II superstring theories. From the resulting S-matrix elements, we read off the precise form of the couplings, including their exact numerical coefficients, of two tachyons and two gauge fields in the corresponding highly symmetric effective field eheory (EFT) Lagrangian in the worldvolume of D-brane-Anti-D-brane to all orders in α′, which modify and complete previous proposals. We verify that the EFT reproduces the infinite collection of stringy gauge field singularities in dual channels. Inspired by interesting similarities between the all-order highly symmetric EFTs and holographic duals of Vasiliev’s higher spin gravities à là Nilsson and Vasiliev, we make a proposal for tensionless limits of D-brane-anti-D-brane systems.
Arginine-dependent immune responses
Authors: Martí i Líndez Adrià-Arnau , Reith Walter 
Published: May 2021

AbstractA growing body of evidence indicates that, over the course of evolution of the immune system, arginine has been selected as a node for the regulation of immune responses. An appropriate supply of arginine has long been associated with the improvement of immune responses. In addition to being a building block for protein synthesis, arginine serves as a substrate for distinct metabolic pathways that profoundly affect immune cell biology; especially macrophage, dendritic cell and T cell immunobiology. Arginine availability, synthesis, and catabolism are highly interrelated aspects of immune responses and their fine-tuning can dictate divergent pro-inflammatory or anti-inflammatory immune outcomes. Here, we review the organismal pathways of arginine metabolism in humans and rodents, as essential modulators of the availability of this semi-essential amino acid for immune cells. We subsequently review well-established and novel findings on the functional impact of arginine biosynthetic and catabolic pathways on the main immune cell lineages. Finally, as arginine has emerged as a molecule impacting on a plethora of immune functions, we integrate key notions on how the disruption or perversion of arginine metabolism is implicated in pathologies ranging from infectious diseases to autoimmunity and cancer.
Is it the coracobrachialis superior muscle, or is it an unidentified rare variant of coracobrachialis muscle?
Authors: Olewnik Łukasz , Zielinska Nicol , Gołek Łukasz , Aragonés Paloma , Sanudo Jose Ramon 
Published: May 2021

AbstractThe coracobrachialis muscle (CBM) originates from the apex of the coracoid process, in common with the short head of the biceps brachii muscle, and from the intermuscular septum. The CBM demonstrates variability in both the proximal and distal attachment, with some extremely rare varieties, such as the coracobrachialis superior, coracobrachialis longus and coracocapsularis muscle. This case report describes an extremely rare variant of the coracobrachialis superior muscle, or a very rare variant of the CBM. Our findings highlight the importance of muscle variants in the shoulder region, especially the coracoid region, and are significant for radiologists, anatomists, physiotherapists and surgeons specializing in the shoulder joint.
Testing for equality of distributions using the concept of (niche) overlap
Authors: Parkinson-Schwarz Judith H. , Bathke Arne C. 
Published: May 2021

AbstractIn this paper, we propose a new non-parametric test for equality of distributions. The test is based on the recently introduced measure of (niche) overlap and its rank-based estimator. As the estimator makes only one basic assumption on the underlying distribution, namely continuity, the test is universal applicable in contrast to many tests that are restricted to only specific scenarios. By construction, the new test is capable of detecting differences in location and scale. It thus complements the large class of rank-based tests that are constructed based on the non-parametric relative effect. In simulations this new test procedure obtained higher power and lower type I error compared to two common tests in several settings. The new procedure shows overall good performance. Together with its simplicity, this test can be used broadly.
In Vitro 1H NMR Metabolic Profiles of Liver, Brain, and Serum in Rats After Chronic Consumption of Alcohol
Authors: Pravdivtseva Mariya S. , Shevelev Oleg B. , Yanshole Vadim V. , Moshkin Mikhail P. , Koptyug Igor V. , Akulov Andrey E. 
Published: May 2021

AbstractThe impact of alcohol on the body can be investigated with NMR spectroscopy in vitro, which can detect a wide range of metabolites but preparing samples includes tissue biopsy. Blood sampling is less invasive, but blood metabolic content might not reflect the changes occurring in other tissues. Thus, this study aimed to investigate the liver, brain, and serum metabolism and evaluate the link between tissues and serum metabolic content. Two experimental groups with ten outbred rats each were provided intragastrically with water (control group) and 50% ethanol solution (alcohol group) for 28 days. 1H NMR spectroscopy in vitro was performed on the brain cortex, liver, and serum samples. Student’s t test with Holm–Bonferroni correction was used to investigate significant differences between groups. Partial least-squares discriminant analysis (PLS-DA) and two-way ANOVA were performed to compare liver and serum, brain and serum. In all, 38, 37, and 21 metabolites were identified in the liver, brain, and serum samples, respectively. Significant differences for three metabolites were found in the liver (alanine, proline, and glutathione, p < 0.002) and four in serum (lactate, betaine, acetate, and formic acid, p < 0.002) were detected between the control and alcohol groups. The contents of glucose, betaine, and isoleucine were correlated (r > 0.65) between serum and liver samples. PLS-DA determined separation between all tissues (p < 0.001) and between control and alcohol groups only for liver and serum (p < 0.001). Alcohol had a more substantial effect on liver and serum metabolism than on the brain.
The Saami and the Karen — common experience and differences: a comparative perspective
Authors: Szpak Agnieszka , Ochwat Maria 
Published: May 2021

AbstractThis paper offers a comparative perspective on a specific issue of the indigenous peoples of the Saami and the Karen. The groups being compared are from Europe and Asia, selected on the basis of their particular circumstances of living in more than one State. However, while the Saami are a relatively well-treated people that enjoy a form of cultural autonomy; the Karen are in a far worse situation with regard to their legal position as well as actual living conditions. The authors examine the cultural, political, and legal aspects of the Saami and the Karen situations and compare their common experience and aspirations. The article attempts to answer the question as to what the similarities and differences between the two indigenous peoples are and what lessons can be learned by those peoples that may be helpful in realizing their aspirations.
The Fundamental Group of a Noncommutative Space
Authors: van Suijlekom Walter D. , Winkel Jeroen 
Published: May 2021

AbstractWe introduce and analyse a general notion of fundamental group for noncommutative spaces, described by differential graded algebras. For this we consider connections on finitely generated projective bimodules over differential graded algebras and show that the category of flat connections on such modules forms a Tannakian category. As such this category can be realised as the category of representations of an affine group scheme G, which in the classical case is (the pro-algebraic completion of) the usual fundamental group. This motivates us to define G to be the fundamental group of the noncommutative space under consideration. The needed assumptions on the differential graded algebra are rather mild and completely natural in the context of noncommutative differential geometry. We establish the appropriate functorial properties, homotopy and Morita invariance of this fundamental group. As an example we find that the fundamental group of the noncommutative torus can be described as the algebraic hull of the topological group $(\mathbb Z+\theta \mathbb Z)^{2}$

(
ℤ
+
𝜃
ℤ
)

2

.
The Limits of Computation
Authors: Powell Andrew 
Published: May 2021

AbstractThis article provides a survey of key papers that characterise computable functions, but also provides some novel insights as follows. It is argued that the power of algorithms is at least as strong as functions that can be proved to be totally computable in type-theoretic translations of subsystems of second-order Zermelo Fraenkel set theory. Moreover, it is claimed that typed systems of the lambda calculus give rise naturally to a functional interpretation of rich systems of types and to a hierarchy of ordinal recursive functionals of arbitrary type that can be reduced by substitution to natural number functions.
Polycyclic aromatic hydrocarbons (PAHs) in soils of an industrial area in semi-arid Uzbekistan: spatial distribution, relationship with trace metals and risk assessment
Authors: Bandowe Benjamin A. Musa , Shukurov Nosir , Leimer Sophia , Kersten Michael , Steinberger Yosef , Wilcke Wolfgang 
Published: May 2021

AbstractThe concentrations, composition patterns, transport and fate of PAHs in semi-arid and arid soils such as in Central Asia are not well known. Such knowledge is required to manage the risk posed by these toxic chemicals to humans and ecosystems in these regions. To fill this knowledge gap, we determined the concentrations of 21 parent PAHs, 4,5-methylenephenanthrene, 6 alkylated PAHs, and biphenyl in soils from 11 sampling locations (0–10, 10–20 cm soil depths) along a 20-km transect downwind from the Almalyk metal mining and metallurgical industrial complex (Almalyk MMC), Uzbekistan. The concentrations of Σ29 PAHs and Σ16 US-EPA PAHs were 41–2670 ng g−1 and 29–1940 ng g−1, respectively. The highest concentration of Σ29 PAHs occurred in the immediate vicinity of the copper smelting factory of the Almalyk MMC. The concentrations in topsoil decreased substantially to a value of ≤ 200 ng g−1 (considered as background concentration) at ≥ 2 km away from the factory. Low molecular weight PAHs dominated the PAH mixtures at less contaminated sites and high molecular weight PAHs at the most contaminated site. The concentration of Σ16 US-EPA PAHs did not exceed the precautionary values set by the soil quality guidelines of, e.g., Switzerland and Germany. Similarly, the benzo[a]pyrene equivalent concentration in soils near the Almalyk MMC did not exceed the value set by the Canadian guidelines for the protection of humans from carcinogenic PAHs in soils. Consequently, the cancer risk due to exposure to PAHs in these soils can be considered as low.
Nāgārjunian-Yogācārian Modal Logic versus Aristotelian Modal Logic
Authors: Schumann Andrew 
Published: May 2021

AbstractThere are two different modal logics: the logic T assuming contingency and the logic K = assuming logical determinism. In the paper, I show that the Aristotelian treatise On Interpretation (Περί ερμηνείας, De Interpretatione) has introduced some modal-logical relationships which correspond to T. In this logic, it is supposed that there are contingent events. The Nāgārjunian treatise Īśvara-kartṛtva-nirākṛtiḥ-viṣṇoḥ-ekakartṛtva-nirākaraṇa has introduced some modal-logical relationships which correspond to K =. In this logic, it is supposed that there is a logical determinism: each event happens necessarily (siddha) or it does not happen necessarily (asiddha). The Nāgārjunian approach was inherited by the Yogācārins who developed, first, the doctrine of causality of all real entities (arthakriyātva) and, second, the doctrine of momentariness of all real entities (kṣaṇikavāda). Both doctrines were a philosophical ground of the Yogācārins for the logical determinism. Hence, Aristotle implicitly used the logic T in his modal reasoning. The Madhyamaka and Yogācāra schools implicitly used the logic K = in their modal reasoning.
Steady-State Serum IgG Trough Levels Are Adequate for Pharmacokinetic Assessment in Patients with Immunodeficiencies Receiving Subcutaneous Immune Globulin
Authors: Li Zhaoyang , McCoy Barbara , Engl Werner , Yel Leman 
Published: May 2021

AbstractPatients with primary immunodeficiency diseases often require lifelong immunoglobulin (IG) therapy. Most clinical trials investigating IG therapies characterize serum immunoglobulin G (IgG) pharmacokinetic (PK) profiles by serially assessing serum IgG levels. This retrospective analysis evaluated whether steady-state serum IgG trough level measurement alone is adequate for PK assessment. Based on individual patient serum IgG trough levels from two pivotal trials (phase 2/3 European [NCT01412385] and North American [NCT01218438]) of weekly 20% subcutaneous IG (SCIG; Cuvitru, Ig20Gly), trough level-predicted IgG AUC (AUCτ,tp) were calculated and compared with the reported AUC calculated from serum IgG concentration-time profiles (AUCτ). In both studies, mean AUCτ,tpvalues for Ig20Gly were essentially equivalent to AUCτwith point estimates of geometric mean ratio (GMR) of AUCτ,tp/AUCτnear 1.0 and 90% CIs within 0.80–1.25. In contrast, for IVIG, 10%, mean AUCτ,tpvalues were lower than AUCτby >20%, (GMR [90% CI]: 0.74 [0.70–0.78] and 0.77 [0.73–0.81] for the two studies, respectively). Mean AUCτ,tpvalues calculated for 4 other SCIG products (based on mean IgG trough levels reported in the literature/labels) were also essentially equivalent to the reported AUCτ(differences <10% for all except HyQvia, a facilitated SCIG product), while differences for IVIG products were >20%. In conclusion, steady-state serum IgG levels following weekly SCIG remain stable, allowing for reliable prediction of AUC over the dosing interval using trough IgG levels. These findings indicate that measuring steady-state serum IgG trough levels alone may be adequate for PK assessment of weekly SCIG.
Bioreactance and fourth-generation pulse contour methods in monitoring cardiac index during off-pump coronary artery bypass surgery
Authors: Ylikauma Laura Anneli , Ohtonen Pasi Petteri , Erkinaro Tiina Maria , Vakkala Merja Annika , Liisanantti Janne Henrik , Satta Jari Uolevi , Juvonen Tatu Sakari , Kaakinen Timo Ilari 
Published: May 2021

AbstractThe pulmonary artery catheter (PAC) is considered the gold standard for cardiac index monitoring. Recently new and less invasive methods to assess cardiac performance have been developed. The aim of our study was to assess the reliability of a non-invasive monitor utilizing bioreactance (Starling SV) and a non-calibrated mini-invasive pulse contour device (FloTrac/EV1000, fourth-generation software) compared to bolus thermodilution technique with PAC (TDCO) during off-pump coronary artery bypass surgery (OPCAB). In this prospective study, 579 simultaneous intra- and postoperative cardiac index measurements obtained with Starling SV, FloTrac/EV1000 and TDCO were compared in 20 patients undergoing OPCAB. The agreement of data was investigated by Bland–Altman plots, while trending ability was assessed by four-quadrant plots with error grids. In comparison with TDCO, Starling SV was associated with a bias of 0.13 L min−1 m−2 (95% confidence interval, 95% CI, 0.07 to 0.18), wide limits of agreement (LOA, − 1.23 to 1.51 L min−1 m−2), a percentage error (PE) of 60.7%, and poor trending ability. In comparison with TDCO, FloTrac was associated with a bias of 0.01 L min−1 m−2 (95% CI − 0.05 to 0.06), wide LOA (− 1.27 to 1.29 L min−1 m−2), a PE of 56.8% and poor trending ability. Both Starling SV and fourth-generation FloTrac showed acceptable mean bias but imprecision due to wide LOA and high PE, and poor trending ability. These findings indicate limited reliability in monitoring cardiac index in patients undergoing OPCAB.
Thermodynamic Properties of the Superconducting State in Metallic Hydrogen: Electronic Correlations, Non-conventional Electron-Phonon Couplings and the Anharmonic Effects
Authors: Kostrzewa M. , Durajski A. P. , Kalaga J. K. , Szczȩśniak R. 
Published: May 2021

AbstractThermodynamical properties of the superconducting state in metallic hydrogen were determined on the basis of the model of two compressed hydrogen planes. We took into account both the on-site and the inter-site electronic correlations (UandK), as well as the relevant non-conventional electron-phonon coupling functions (gUandgK). We proved, within the Eliashberg formalism, that the maximum value of the critical temperature of transition into the superconducting state is about 200 K for the harmonic approximation, and about 84 K for the Morse anharmonic approximation. Omission of the electronic correlations results in a considerable overstatement of theTCvalue. On the other hand, theTCvalue is remarkably understated if the non-conventional interactions are disregarded. Other thermodynamic quantities, such as the order parameter, the jump in the specific heat value, the thermodynamic critical field, and the upper critical field, take the values for which the non-dimensional ratiosRΔ,RC,RHandRH2do not differ substantially from the predictions of the BCS theory.