bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indole-3-propionic acid reduces lipid peroxidation induced by potassium iodate in porcine thyroid
Authors: Iwan Paulina , Karbownik-Lewinska Malgorzata 
Published: February 2025

Abstract
Iodine is a trace element indispensable for thyroid hormone biosynthesis but its deficiency is a global problem. Programs of iodine prophylaxis are frequently based on salt iodization with the use of potassium iodate (KIO3), which, however, reveals potential prooxi-dative properties. Indole-3-propionic acid (IPA), deamination product of tryptophan, is an effective antioxidant without prooxidative properties. We have shown in our previous study that melatonin is able to reduce lipid peroxidation caused by KIO3. Taking into account the similarity between melatonin and IPA we decided to evaluate potential protective effects of this compound against KIO3-induced lipid peroxidation in porcine thyroid homogenates. In the current study thyroid homogenates were incubated in the presence of different concentrations of KIO3 without/with IPA. Six experiments were performed with different concentrations of IPA. Malondialdehyde+4-hydroxyalkenals (MDA+4-HDA) concentration (LPO index) was measured spectrophotometrically. IPA reduced in concentration-dependent manner (with statistical significance for concentrations of 10 mM, 7.5 mM, 5.0 mM) KIO3-induced lipid peroxidation, but only when KIO3 was used in concentrations of 10 mM and 7.5 mM, which are close to physiological iodine concentration in the thyroid (i.e. ~10 mM). In conclusion, IPA might be considered as a pharmacological agent to be used for protection against prooxidative effects of iodates.
Osmotic fragility during in vitro erythrocyte cytotoxicity induced by aluminium chloride, lead acetate or mercuric chloride in hyposmolar sucrose media
Authors: Igbokwe Nanacha Afifi , Igbokwe Ikechukwu Onyebuchi 
Published: February 2025

Abstract
Erythrocyte death by eryptosis or erythronecrosis may induce erythrocyte shrinking or swelling with increase in osmotic resistance or fragility as indication of cytotoxicity. We investigated heterogeneous cytotoxic outcomes during in vitro exposure of goat erythrocytes to aluminium chloride, lead acetate or mercuric chloride using erythrocyte osmotic fragility (EOF) testing. The metallic salt solution (MSS) was added to 4.0 μL of high (100 mosmol/L) and low (250 mosmol/L) hyposmolar sucrose media at 0.3 or 0.4 mosmol/L concentration during testing of the osmotic fragility of 5.0 μL of blood from 10 goats. Hemolysis induced in the media (with and without MSS) was estimated in the supernatant with spectrophotometer at 540 nm. Osmotic stabilization or destabilization was calculated with probability for each test. Inducible osmotic resistance (IOR) was the ratio of mean stabilization to destabilization in both high and low hyposmolar media. Each MSS induced both osmotic resistance (stabilization) and fragility (destabilization) in varied media concentrations, with greater likelihood (P) of stabilization (0.93) or destabilization (0.77) in high or low media hyposmolarity, respectively. The EOF outcomes of the goats diverged within the group. High IOR induced by mercuric chloride (2.90) and low IOR by lead acetate (0.07) and aluminium chloride (0.04) reflected high stabilizing and destabilizing outcomes, respectively. In conclusion, MSS induced dual EOF outcomes (stabilization or destabilization) on the fragility domain, suggesting occurrence of both eryptosis (as stabilization) and erythronecrosis (as destabilization) at low exposure level, whereby biphasic, nonmonotonic or hormetic response to MSS toxic action might exist.
Cardioprotective effect of citicoline against arsenic trioxide-induced injury in H9C2 cell line
Authors: Fallah Fahimeh , Aminzadeh Azadeh 
Published: February 2025

Abstract
Cardiotoxicity is one of the most serious adverse effects of exposure to arsenic. It has been shown that cytidine 5′-diphosphocholine or citicoline exerts a variety of biological functions, including anti-inflammatory and antioxidant activities. The aim of current study was to investigate the effect of citicoline on arsenic trioxide (ATO)-induced cardiotoxicity in H9C2 cells. H9C2 cardiac cells exposed to ATO for 24 h to induce cytotoxicity. The cells were pre-incubated with citicoline for 72 h prior to the exposure to ATO. The effect of citicoline on cell viability was investigated by MTT method. Malondialdehyde (MDA), total thiol groups, and total antioxidant power (TAP) levels were also evaluated. The results indicated that citicoline could effectively enhanced cell viability of H9C2 cells exposed to ATO. Treatment with ATO increased MDA levels, while pretreatment with citicoline reduced lipid peroxidation. Moreover, it could enhance total thiol contents and TAP levels. Taken together, our data suggest that citicoline has protective effects against ATO-induced oxidative stress in H9C2 cells, that could be attributed to inhibition of oxidative stress and its antioxidant effects.
DYNAMIC CAPABILITIES AND CATUR PARAMITHA: THE MEDIATION AND MODERATION ROLE FOR BUSINESS PERFORMANCE
Authors: Indrawati Ayu Desi , Triaryati Nyoman , Arsawan Wayan Edi 
Published: February 2025

Ketidakkonsistenan temuan hubungan orientasi kewirausahaan dan kinerja bisnis ini mendorong perlunya melakukan investigasi lanjutan untuk memperjelas hubungan kedua konstruk sekaligus menambah literatur relevan. Riset ini bertujuan untuk menginvestigasi kapabilitas dinamis dan Catur Paramitha sebagai mediator dan moderator dalam pengaruh orientasi kewirausahaan pada kinerja bisnis dan juga menguji pengaruh orientasi kewirausahan, kapabilitas dinamis, dan Catur Paramitha pada kinerja bisnis. Penelitian ini menggunakan pendekatan kuantitatif yang melibatkan 300 unit UKM kerangka sampel di Indonesia danvdianalisis dengan software SmartPLS. Hasil temuan mengindikasikan tingkat orientasi kewirausahaan yang kuat akan meningkatkan kemampuan dinamis UKM organisasi, sehingga tercipta sumber daya unik, langka, dan berharga sebagai kompetensi inti untuk menciptakan kinerja bisnis yang unggul. Selanjutnya, kapabilitas dinamis berperan menambah (mediasi parsial komplementer) pengaruh orientasi kewirausahaan pada kinerja bisnis, dan Catur Paramitha sebagai nilai kearifan local memiliki peran memperkuat (moderasi) pengaruh orientasi kewirausahaan pada peningkatan kinerja bisnis UKM. Penelitian ini menyoroti pentingnya peran orientasi kewirausahaan, kapabilitas dinamis, dan Catur Paramitha sebagai sumber daya unggulan organisasi dalam mewujudkan kinerja bisnis yang optimal.
Authors: Cahyanti N. N. A. T. , Asih I. A. R. A. , Widihati I. A. G. 
Published: February 2025

ABSTRAK
Korosi merupakan fenomena alam yang dapat merusak material logam seperti baja St-37 dan juga menyebabkan degradasi struktur serta penurunan kinerja material logam. Beberapa penelitian telah dilakukan untuk mengembangkan inhibitor korosi sebagai solusi yang efektif. Salah satu bahan alam yang digunakan sebagai inhibitor korosi adalah ekstrak daun lemon, yaitu senyawa kimia yang ditambahkan ke lingkungan korosif untuk menghambat atau mencegah reaksi oksidasi logam. Penelitian ini bertujuan untuk mengetahui laju korosi baja St-37 dalam media korosif NaCl dan HCl serta efisiensi inhibisi penggunaan inhibitor ekstrak daun lemon dengan berbagai konsentrasi untuk mencegah korosi. Daun lemon diekstraksi menggunakan metode maserasi, kemudian ekstrak tersebut diuji kandungan metabolit sekundernya. Laju korosi ditentukan menggunakan metode kehilangan berat. Hasil uji fitokimia menunjukkan bahwa ekstrak daun lemon positif mengandung alkaloid, fenol, flavonoid, tanin, dan tanin terkondensasi. Laju korosi terendah baja St-37 pada media korosif NaCl dan HCl masing-masing sebesar 0,1685 dan 0,0658 mmpy (millimetre per year), dan efisiensi inhibibisi tertinggi untuk melindungi media korosif masing-masing sebesar 96,6963 dan 40,3065%, dicapai pada konsentrasi inhibitor 500 ppm. Pengurangan laju korosi dan efisiensi penghambatan oleh ekstrak daun lemon pada baja S-37 dalam media korosif HCl lebih baik daripada dalam media NaCl.
Kata kunci: Efisiensi inhibisi, Inhibitor, Korosi, Laju korosi, Lemon
ABSTRACT
Corrosion is a natural phenomenon that can damage metal materials such as St-37 steel and also causes structural degradation and decreased performance of metal materials. Several studies have been conducted to develop corrosion inhibitors as an effective solution. One of the natural products used as a corrosion inhibitor is lemon leaf extract, a chemical compound added to corrosive environments to inhibit or prevent metal oxidation reactions. This study aimed to determine the corrosion rate of St-37 steel in NaCl and HCl corrosive media and the inhibition efficiency of using lemon leaf extract inhibitors with varying concentrations to prevent corrosion. Lemon leaves were extracted using the maceration method, and then the extract was tested for secondary metabolite content. The corrosion rate was determined using the weight loss method. The results of the phytochemical test showed that lemon leaf extract positively contained alkaloids, phenols, flavonoids, tannins, and condensed tannins. The lowest corrosion rate of the St-37 steel in the NaCl and HCl corrosive media of 0.1685 and 0.0658 mmpy (millimeter per year), respectively, and the highest efficiency of the inhibitor to protect corrosive media of 96.6963 and 40.3065%, respectively, were achieved at the inhibitor concentration of 500 ppm. The corrosion rate reduction and the inhibition efficiency by lemon leaf extract on the S-37 steel in HCl corrosive media was better than in NaCl media.
Keywords: Corrosion, Corrosion rate, Inhibition efficiency, Inhibitor, Lemon
Experimenting with Sensorimotor Play to Enhance Learning Attention and Cognitive Function in Children at TK SPNF SKB Denpasar
Authors: Ratini Ni Kadek , Narta Dewi Anak Ayu Nyoman Trisna , Nugraha Made Hendra Satria , Utama Anak Agung Gede Eka Septian 
Published: February 2025

Introduction: Children need attention and education from their families, schools, and communities to support their development. Cognitive function, especially attention, is vital for their learning process. Previous studies have shown suboptimal cognitive function (average digit span test score of 4.31) and decreased attention during lessons, evidenced by frequent seat changes and talking. Enhancing these areas through sensorimotor play can create more engaging and enjoyable learning experiences for children.
Methods: This quasi-experimental study utilized consecutive sampling to determine a sample size of 30 children based on Pocock's formula. Two classes from TK SPNF SKB were randomly selected, and subjects were assessed for eligibility based on inclusion and exclusion criteria. The subjects were randomly divided into 15 children in the intervention group and 15 in the control group. The intervention group participated in sensorimotor play sessions three times a week for three weeks, totaling nine sessions, each lasting 30-35 minutes. The control group did not receive any intervention.
Results: Data analysis using paired sample t-tests demonstrated a significant improvement in the intervention group's learning attention (p = 0.001) and cognitive function (p = 0.001). Independent t-test results indicated an essential difference between the two groups post-intervention (p = 0.001).
Conclusion: Sensorimotor play effectively enhances attention and cognitive function in children.

Keywords: sensorimotor play, learning attention, cognitive function
Об уникальном опыте работы в СП «Вьетсовпетро» и особенностях коммуникации в интернациональном коллективе
Authors: СУЧКОВА Елена Валерьевна 
Published: February 2025

Автор – бывший сотрудник совместного российско-вьетнамского нефтедобывающего предприятия «Вьетсовпетро», флагмана нефтегазовой промышленности во Вьетнаме с мощной материально-технической базой, ресурсами и квалифицированными международными кадрами. В данном материале автор поделился опытом работы и преподавания вьетнамского языка для российских коллег и опытом создания коммуникационного мостика для большего понимания и сближения сотрудников, занимающихся важным делом для наших стран.
The author is a former employee of the joint Russian—Vietnamese oil production enterprise "Vietsovpetro", the flagship of the oil and gas industry in Vietnam with a powerful logistical base, resources and qualified international staff. In this article, the author shared her experience of working and teaching Vietnamese to Russian colleagues and the experience of creating a communication bridge for greater understanding and rapprochement of employees involved in an important matter for our countries.
Научные публикации на страницах "Известий Восточного института" (1900–1915 гг.): источниковедческий обзор
Authors: КАРАМАН Вадим Николаевич 
Published: February 2025

Статья посвящена историографическому обзору научных публикаций на страницах "Известий Восточного института" в первые десятилетия его существования. Выделены научные направления, освещённые авторами, и то, как ими понимались эти направления и как они эволюционировали в отмеченный период. Отмечены проблемы, с которыми сталкиваются исследователи при обращении к изданиям первых лет XX века. Дана краткая характеристика развития самого журнала. Также часть материала отведена анализу не строго научных материалов (учебных и служебных), необходимых для понимания деятельности самого журнала.
The article is devoted to a historiographic review of academic publications on the pages of the " Oriental Institute Journal " in the first decades of its existence. The academic directions covered by the authors and how they understood these directions and how they evolved in the noted period are highlighted. The problems that researchers encounter when referring to publications of the first years of the 20th century are noted. A brief description of the development of the journal itself is given. Also, part of the material is devoted to the analysis of non-strictly academic materials (educational and service) necessary for understanding the activities of the journal itself.
Pengetahuan mengenai anestesi dan peran dokter spesialis anestesi pada mahasiswa psikologi Universitas Tarumanagara
Authors: Cheryl Claudia Angelica , Atzmardina Zita 
Published: February 2025

Pasien terkadang tidak menyadari bahwa dokter spesialis anestesi ialah seorang dokter spesialis dan memiliki peran di luar ruang operasi. Kurangnya pengetahuan tentang bidang anestesi dan peran dokter spesialis anestesi ini dapat membuat dokter spesialis anestesi merasa kurang dihargai. Oleh karena itu, kami merasa perlu untuk mengeksplorasi pengetahuan sebuah kepompok orang, dalam hal ini mahasiswa dari jurusan psikologi, tentang anestesi dan peran seorang dokter spesialis anestesi. Studi deskriptif ini dilakukan terhadap 118 mahasiswa psikologi yang diberikan kuesioner pengetahuan terkait anestesi dan peran dokter spesialis anestesi. Hasil studi didapatkan jumlah mahasiswa yang memiliki pengetahuan baik mengenai anestesi (49,2%), peran dokter spesialis anestesi (61,1%), dan baik anestesi maupun peran dokter spesialis anestesi (63,6%). Lebih dari 90% mahasiswa mengetahui bahwa dokter spesialis anestesi bertanggung jawab untuk memantau tanda vital pasien, dan mayoritas juga dapat mengidentifikasi komplikasi anestesi ringan atau berat. Hasil studi ini bertentangan dengan keyakinan bahwa masyarakat umum memiliki pengetahuan yang tidak memadai mengenai anestesi dan peran dokter spesialis anestesi.
Implementasi “Lima Prinsip Tepat” terapi anti hipertensi pada lansia di panti wreda
Authors: Tiranda Wisasti Gladys Chantika , Gunawan Shirly 
Published: February 2025

Hipertensi merupakan salah satu penyebab utama mortalitas dan morbiditas di Indonesia. Prevalensinya meningkat seiring bertambahnya usia. Pengobatan yang tepat akan mendukung keberhasilan pengelolaan hipertensi, terutama pada lansia. Pengobatan yang tepat melibatkan lima prinsip tepat: tepat pasien, tepat obat, tepat dosis, tepat waktu, dan tepat rute pemberian. Penelitian ini akan menggambarkan ketepatan penggunaan obat antihipertensi pada lansia di panti werda. Metode yang digunakan dalam penelitian ini ialah deskriptif dengan desain cross-sectional. Data diperoleh dari kuesioner dengan pemilihan sampel menggunakan teknik non-random sampling sesuai dengan kriteria inklusi. Subjek studi ini ialah lansia yang tinggal di panti werda di Tangerang dan Cibubur. Hasil studi menunjukkan bahwa 62 lansia di panti jompo menderita hipertensi, yang didominasi oleh perempuan (71%). Sebagian besar dari mereka menderita hipertensi derajat I (87,1%), hipertensi sistolik terisolasi (11,3%), dan hipertensi derajat II (1,6%). Amlodipin merupakan obat yang paling banyak digunakan sebagai monoterapi, sedangkan untuk kombinasi, amlodipin dan candesartan merupakan terapi kombinasi hipertensi yang paling banyak digunakan. Lima prinsip tepat dalam pengobatan (tepat pasien, tepat obat, tepat dosis, tepat waktu, dan tepat rute) telah diimplementasikan dengan cukup baik pada lansia yang mengonsumsi obat antihipertensi di panti werda.
Heeding the Song Unseen
Authors: Bell Anne 
Published: February 2025

If one descends the Tatshenshini River* in July, one is bound to come across the .hermit thrush hopping about under the poplar, willow and scrubby spruce. A reclusive bird, its name seems to suit its unassuming appearance and the sparse, rugged surroundings in which I first heard it sing.. Like a small brown robin deprived of its orange breast, it could easily pass unnoticed, and I myself would scarcely have paid it much attention had it not been for its song, a splash of delicate, resonant crystal and sparkling cascades. [...]
Water Supersaturated by Ultrafine Bubble CO2 for Maximizing Potential of Geological Sequestration
Authors: Aoki J. , Ueda R. , Suganuma T. , Goto A. , Okano Y. , Tamagawa T. 
Published: February 2025

Abstract
A conventional geological carbon dioxide (CO2) sequestration has risks of leakage and insufficient utilization of storage capacity. These undesirable phenomena are attributed to the separation of CO2 due to gravitational effects. Carbonated water injection is one approach to solve the technical challenges, however it has limited CO2 content per unit volume. Ultrafine bubble (UFB) technology has the potential to increase the CO2 content in the carbonated water, i.e. the water becomes supersaturated with CO2 by dispersing CO2-UFBs. The UFBs less than 1 μm in diameter have a small buoyancy and maintain the stability of them for a long duration. Because CO2-supersaturated water has the potential to suppress the reduction in sweep efficiency caused by the difference in viscosity with in-situ fluid, the risk of insufficient pore space utilization can be minimized. The knowledge of UFB under high pressure has rarely been reported and is crucial for designing CO2-UFB injection systems. Experiments on CO2-UFB under high pressure were carried out in this study. Five additives, i.e. trisiloxane, calcium carbonate particle, oleic acid, ethanol and saponin, were tested to make the UFB and the CO2 content more stable. A Simulation study was also conducted to examine effective injection strategies. As a result, the following conclusions were achieved: (1) 30-40 vol.% of CO2 can be dispersed in water as UFBs and maintained for approximately 120 minutes by using trisiloxane. However, the UFBs at high temperatures become unstable immediately. (2) The other additives, except for calcium carbonate particles, also have an effect on increasing the CO2 content in the water. The maximum increase ratio of the CO2 content in the solubility is 10%. (3) Numerical flow simulations have suggested that the CO2-UFB injection carries minimal risk of CO2-leakage to the surface and can improve sweep efficiency.
Downhole Venturi Flowmeter with Removable Orifice
Authors: Lowes E. M. , Cook T. 
Published: February 2025

Abstract
This paper presents the use of a downhole venturi flowmeter in a water injection dump flood well to monitor injection rates. The venturi installed downhole features a unique removable orifice which can be retrieved on wireline to facilitate an array of well interventions.
A proposal to convert a producing oil well in the Western Flank of the Cooper Basin, central Australia to a water injection dump flood well included fracture stimulation and ongoing downhole rate measurement to monitor injectivity. For downhole rate measurement, two preferred options were evaluated: regular memory production logs on slickline for intermittent measurement or downhole venturi with continuous measurement and surface output. Due to the higher ongoing intervention monitoring costs and the irregularity of the acquisition associated with a Memory Production Log, the venturi and pressure gauge combination emerged as the preferred option. At the time, venturis on the Australian market featured fixed orifices or wedges, limiting through bore access, and potentially hindering much needed fracture stimulation and future through tubing well intervention activities. A novel solution was needed.
Facing this challenge, the operator collaborated with their downhole gauge provider to conceptualize a bespoke, cost-effective venturi. This innovative solution features an orifice which could be removed and replaced on slickline. The resultant equipment not only satisfied the requirement to measure the rate of water injection but also allowed through bore access in the completion to facilitate fracture stimulation and well intervention activities, and offered flexibility to change the orifice size, accommodating various injection rates. The venturi flowmeter sub and downhole gauges were installed as part of the permanent completion in January 2024. After successful fracture stimulation of the well, the orifice tool was installed in the flowmeter sub. From the measured pressures either side of the orifice, a dump flood rate was inferred.
The collaboration has resulted in an efficient and versatile venturi design tailored to the specific needs of the well which also reduces ongoing intervention risk. Dependent on the performance of the dump flood it will be possible to retrieve and change out the orifice to suit the flowing conditions without needing to pull the completion.