bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction of Academic Motivation Based on Variables of Personality Traits, Academic Self-Efficacy, Academic Alienation and Social Support in Paramedical Students
Authors: Ahmadi Ahmad , Ziapour Arash , lebni Javad Yoosefi , Mehedi Nafiul 
Published: March 2021

Background Academic motivation is one of the indices of success in scientific activities. Therefore, the goal of the present research is to predict academic motivation based on variables of personality traits, academic self-efficacy, academic alienation, and social support in students studying in different fields of paramedicine. Method The research was correlation-descriptive in which 183 paramedical university students in the academic year of 2019-2020 were selected by a two-stage cluster random sampling method, studying in the Kermanshah University of Medical Sciences. The data were collected through the Vallerand Academic Motivation questionnaire, NEO Personality Inventory Test, Sherer Self-Efficacy questionnaire, Fleming Social Support questionnaire, and Johnson Academic Alienation, and the collected data were analyzed (Pearson correlation coefficient and multiple regression) using SPSS V.22 software. Findings The results showed that personality traits of extroversion ([Formula: see text]), openness to experience ([Formula: see text]), conscientiousness ([Formula: see text]), and self-efficacy could predict academic motivation, significantly; but neuroticism ([Formula: see text]), and academic alienation ([Formula: see text]) reversely related to academic motivation. Self-efficacy ([Formula: see text]) could significantly predict academic motivation. There was also a significant relationship between social support and academic motivation. Conclusion The results of the research illustrated that some of the personality traits and self-efficacy had a positive role in predicting academic motivation among paramedical students, and neuroticism and alienation had a reverse negative role in academic motivation. Therefore, in order to promote the academic level of students, it is necessary to improve the harmful effects of self-efficacy and some personality traits that improve better learning performance and quality.
Comparison of the Effect of Traffic Park-Based and School-Based Educational Interventions on Safe Road Crossing in Yazd Elementary School Students
Authors: Zare Asma , Dehghanitafti Abbas Ali , Rahaei Zohreh , Jambarsang Sara , Tolide Marzieh 
Published: March 2021

Introduction Traffic accidents are one of the most important health problems that cause many deaths every year. Scientific-practical interventions are needed to prevent traffic accidents. This study aimed to compare the effectiveness of traffic-based and school-based interventions on the safe road crossing in Yazd elementary school students. Methods This interventional study was conducted on 132 students (66 males and 66 females) in two groups of school-based and traffic park-based intervention. A questionnaire was used to determine the safe crossing behavior score. Then, an educational intervention was administered to both groups. Two months after the intervention, safe crossing behavior was evaluated in both groups. Finally, the data were analyzed using SPSS software version 22. Results In both groups, the score of safe crossing behavior was significantly increased after the intervention. The school-based group had significantly better behaviors compared to the traffic park-based group (P=0.001). There was a significant difference in the mean score of behavior between males and females and the intervention had a greater effect on female students (P=0.017). Conclusion Educational interventions and especially school-based intervention can be effective in improving the students' safe crossing behaviors.
Research on coupled vibrations of driveshaft–rear axle system based on nonlinear hybrid model
Authors: Zou Lin , Lie Yujun , Jia Bing , Qin Ao , Xu Jinli 
Published: March 2021

The transmission shaft–rear axle system is consisted of universal joint, hypoid gear pair, tapered roller bearing, and half shaft. In this article, as a combination of system dynamics and structure dynamics, a hybrid dynamic model of the bending–torsional–shaft vibration of the driveshaft main reducer was established to study its noise vibration harshness performance. Through dynamic frequency sweep analysis, it is found that the natural frequency of torsional vibration of the system is 53.96 Hz. Getting the natural frequency of the torsional vibration of the systems being 57 Hz by the bench tests and Adams simulations. The correctness of the nonlinear hybrid model of the driveshaft–rear axle system is proved. This research will be beneficial to the design, monitoring, and fault detection of the automobile transmission system.
Trastuzumab and pertuzumab in hemodialysis: A case report
Authors: Gaertner Kelly M , Poornima Indu G , Hilton Christie 
Published: March 2021

Introduction Trastuzumab and pertuzumab are recombinant humanized monoclonal antibodies targeting human epidermal growth factor receptor 2 (HER2). Currently, six reported cases on the use of trastuzumab in dialysis, and one on the use of pertuzumab, have been identified in the literature. This case is one of the first to describe the use of pertuzumab, and adds to currently available reports on the use of trastuzumab, in hemodialysis. Case report A female receiving hemodialysis three times per week was diagnosed with a clinical T2N1M0, hormone receptor-negative, HER2-positive, invasive ductal carcinoma of the breast. She received six cycles of neoadjuvant docetaxel, carboplatin, trastuzumab, and pertuzumab, with left ventricular ejection fraction (LVEF) remaining stable throughout. Following surgery, she continued dual HER2 blockade with trastuzumab and pertuzumab, after six cycles of which she was found on routine echocardiogram to have an asymptomatic decline in LVEF. Management & outcome: Following the decline in LVEF, trastuzumab and pertuzumab were held, and cardio-oncology was consulted. LVEF recovered within one month, after which she continued on single-agent trastuzumab to complete one year of HER2-directed therapy. Discussion To our knowledge, this is one of the first published cases describing the use of pertuzumab in a patient receiving hemodialysis. Though our patient did experience a reversible decline in LVEF following twelve cycles of combination trastuzumab and pertuzumab, this case demonstrates the relatively safe and effective use of pertuzumab in a patient with end-stage renal disease undergoing hemodialysis, and lends additional support to the use of trastuzumab in this particular patient population.
Publication rates of hematology/oncology abstracts presented at major pharmacy association meetings
Authors: Wooten Kiley M , Arnall Justin R , Bowser Kiarra M , J Pennell Laurie , Wade-Davis Jazmin N , Olin Jacqueline L , Taylor Margaret , Moore Donald C 
Published: March 2021

Introduction Professional conferences are where research findings are initially presented. Studies suggest many research ideas presented at conferences are never published. Previous studies have demonstrated that the full publication rate of abstracts presented at pharmacy meetings is approximately 20%. The objective of this study was to determine the full publication rate of hematology/oncology abstracts presented at major pharmacy organization annual meetings. Methods A systematic search of PubMed and Google Scholar was performed. Publication status was evaluated for hematology/oncology abstracts presented at annual meetings for the following organizations: American College of Clinical Pharmacy Annual Meeting, American Society of Health-System Pharmacists Midyear Clinical Meeting, Hematology/Oncology Pharmacy Association Annual Meeting, and International Society of Oncology Pharmacy Practitioners Annual Meeting. Data collected included the meeting of abstract presentation, number of authors, abstract study type, country of origin, journal of publication, and type of publication. Abstracts presented as trainee research were excluded. Results Of 451 oncology abstracts evaluated, the most common topic categories included pharmacotherapy (n = 244; 54.1%), clinical pharmacy practice (n = 84; 18.6%), and operational/compounding (n = 69; 15.3%). The overall publication rate was 17.5% (n = 79). Abstracts were published as full manuscripts over a spread of 48 different journals. Factors associated with full publication included abstracts with more than 5 authors (OR 3.86, 95% CI 2.32-6.43; p < 0.0001) and abstracts presented at oncology-focused pharmacy meetings (OR 2.92, 95% CI 1.49-5.72; p = 0.0018). Conclusion This study showed an overall publication rate of 17.5% for abstracts presented at pharmacy meetings, consistent with prior studies.
Plasma levels of tissue inhibitor of metalloproteinase-1 in patients with type 1 diabetes mellitus associate with early diabetic neuropathy and nephropathy
Authors: Papadopoulou-Marketou Nektaria , Whiss Per A , Eriksson Andreas C , Hyllienmark Lars , Papassotiriou Ioannis , Wahlberg Jeanette 
Published: March 2021

Background: Tissue inhibitor of metalloproteinase-1 (TIMP-1) has been suggested as a marker for abnormal regulation of tissue remodelling in type 1 diabetes. Metalloproteinase-9 (MMP-9) has been associated with matrix turnover, and Neutrophil gelatinase associated lipocalin (NGAL) is a marker of tubular injury in diabetic nephropathy. The aim was to analyse these biomarkers to unmask early diabetic complications. Methods: Thirty-three type 1 diabetes patients, aged 20–35 years, and disease duration 20 ± 5.3 years were included. Along with clinical examination, neurophysiological measurements, routine biochemistry, plasma concentrations of TIMP-1, MMP-9 and NGAL were determined with immunoenzymatic techniques. Results: TIMP-1 correlated with abnormal unilateral and bilateral vibratory sense foot perception ( r = −0.49 and r = −0.51, respectively), foot neuropathy impairment assessment score (NIA; r = −0.55), neuropathy symptom assessment score ( r = 0.42), microalbuminuria ( r = 0.50) and eGFR ( r = −0.45). MMP-9 correlated with impaired foot NIA ( r = 0.51). Multiple regression analysis showed an association for TIMP-1 ( p = 0.004) with impaired neurophysiological examinations and renal dysfunction along with NGAL ( p = 0.016 and p = 0.015 respectively). Conclusions: This study suggests that plasma levels of TIMP-1, MMP-9 and NGAL may serve as useful biomarkers in unravelling subclinical neuropathy and nephropathy in type 1 diabetes.
Developing Culturally Tailored mHealth Tools to Address Sexual and Reproductive Health Outcomes Among Black and Latina Women: A Systematic Review
Authors: Chandler Rasheeta , Guillaume Dominique , Parker Andrea , Wells Jessica , Hernandez Natalie D. 
Published: March 2021

Background In addressing the sexual and reproductive health (SRH) disparities for Black and Latina women, there is a need for the development of innovative programs, framed using theoretical underpinnings that are culturally and contextually tailored so that they align with lived experiences. Mobile health (mHealth) interventions offer considerable potential as a means of providing effective SRH education and services. However, there has been a lack of research assessing culturally and contextually tailored mHealth SRH interventions for Black and Latina women. Method A comprehensive literature search was undertaken using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Literature was reviewed to evaluate whether a culturally and contextually tailored approach was utilized in the development and implementation of mHealth interventions for Black and Latina women. Results A total of 12 articles were included in our synthesis, which encompassed mobile phone–, telephone-, and computer-based mHealth interventions for Black and Latina women. Cultural and/or gender-specific tailoring was included in 10 studies. Reduction of risky sexual behaviors and increased contraception usage were reported in 92% ( n = 11) of the studies. Interventions that incorporated tailored content and fostered interaction reported high rates of follow-up. Conclusions Tailored mHealth interventions can be effective in promoting behavior change and improving SRH outcomes for Black and Latina women. However, there is a need for more research assessing user engagement and retention for Black and Latina women, and whether improvements in SRH outcomes are sustainable over the long term.
Anal and urinary incontinence in nulliparous women – Prevalence and associated risk factors
Authors: Okeahialam Nicola A , Thakar Ranee , Ilczyszyn Andrei , Sultan Abdul H 
Published: March 2021

Objective To establish the prevalence and risk factors of urinary and anal incontinence in nulliparous women. Study design Thirty-one catholic convents were sent a validated questionnaire to determine the prevalence and severity of urinary incontinence, and a similarly structured questionnaire to assess anal incontinence. Multivariable regression models were used to determine independent risk factors associated with the likelihood of urinary incontinence or anal incontinence. Main outcome measures Urine/faecal/flatal incontinence and symptom severity. Results Of 202 nuns, 167 (83%) returned the questionnaire. Twenty-two women were excluded due to history of childbirth. Of 145 nulliparous women, 56.2% reported urinary incontinence and 53.8% reported anal incontinence. Women aged 66–76 years had significantly increased odds of experiencing urinary incontinence in comparison to women aged 40–65 years: OR: 2.35 (95% CI: 1.02–5.45) ( p = 0.04). The risk of urinary incontinence was increased in women with a body mass index ≥ 30 in comparison to those with a body mass index < 19: OR: 6.25 (95% CI: 1.03–38.08) ( p = 0.04). With regards to anal incontinence, although none of the differences with age and body mass index groups reached statistical significance, there was a trend towards women in higher body mass index groups having an increased prevalence of anal incontinence. Current/previous hormonal replacement therapy was also associated with significantly increased odds of experiencing urinary incontinence: OR: 2.53 (95% CI: 1.01–6.36), ( p = 0.04). However, when adjusting for age and body mass index, there was no significant association with urinary incontinence. Conclusions This study highlights that while childbirth is an important risk factor, urinary incontinence and anal incontinence also occur in over 50% of nulliparous women. Additional studies are required to identify other risk factors that may be associated with incontinence in this population.
Systematic review of cost-effectiveness analysis of behavior change communication apps: Assessment of key methods
Authors: Hazel Cynthia Afedi , Bull Sheana , Greenwell Elizabeth , Bunik Maya , Puma Jini , Perraillon Marcelo 
Published: March 2021

Objective Evidence backing the effectiveness of mobile health technology is growing, and behavior change communication applications (apps) are fast becoming a useful platform for behavioral health programs. However, data to support the cost-effectiveness of these interventions are limited. Suggestions for overcoming the low output of economic data include addressing the methodological challenges for conducting cost-effectiveness analysis of behavior change app programs. This study is a systematic review of cost-effectiveness analyses of behavior change communication apps and a documentation of the reported challenges for investigating their cost-effectiveness. Materials and methods Four academic databases: Medline (Ovid), CINAHL, EMBASE and Google Scholar, were searched. Eligibility criteria included original articles that use a cost-effectiveness evaluation method, published between 2008 and 2018, and in the English language. Results Out of the 60 potentially eligible studies, 6 used cost-effectiveness analysis method and met the inclusion criteria. Conclusion The evidence to support the cost-effectiveness of behavior change communication apps is insufficient, with all studies reporting significant study challenges for estimating program costs and outcomes. The main challenges included limited or lack of cost data, inappropriate cost measures, difficulty with identifying and quantifying app effectiveness, representing app effects as Quality-adjusted Life Years, and aggregating cost and effects into a single quantitative measure like Incremental Cost Effectiveness Ratio. These challenges highlight the need for comprehensive economic evaluation methods that balance app data quality issues with practical concerns. This would likely improve the usefulness of cost-effectiveness data for decisions on adoption, implementation, scalability, sustainability, and the benefits of broader healthcare investments.
Arkansans’ Preferred COVID-19 Testing Locations
Authors: McElfish Pearl A. , Willis Don E. , Bryant-Moore Keneshia , Rojo Martha O. , Andersen Jennifer A. , Kaminicki Kyle F. , James Laura P. 
Published: March 2021

Introduction: A contributing factor to racial and ethnic disparities during the COVID-19 pandemic may be the accessibility and acceptability of COVID-19 testing. Previous studies found that access to testing has not been equitable across several sociodemographic indicators. This study documents the preferred testing locations and examines differences across sociodemographic factors with a specific focus on race and ethnicity. Methods: This study includes a primary analysis of cross-sectional data using a self-administered digital survey distributed to Arkansas residents using ARresearch, a volunteer research participant registry. The survey had 1288 responses, and 1221 met eligibility criteria for inclusion in the survey. Participants provided sociodemographic information and were asked to select up to 3 preferred testing locations from 12 options. Chi-square tests assessed differences in testing site preference across relevant sociodemographic groups. Results: Participants preferred drive-through clinics as their top location for COVID-19 testing, with 55% reporting this was their preferred method of testing. This pattern was consistent across all comparison groups (ie, age, sex, race/ethnicity, education, insurance status). Significant differences in testing location preference were observed across age, race and ethnicity, and education, with the most differences observed across race and ethnicity. Conclusion: This study reveals that race and ethnicity are important to consider when deciding where to offer COVID-19 testing. The preferences for testing locations among the most vulnerable demographics will be used to develop targeted responses aimed at eliminating disparities in COVID-19 in Arkansas.
Sex differences in the link between blood cobalt concentrations and insulin resistance in adults without diabetes
Authors: Chen Yong , Huang Haobin , He Xiaowei , Duan Weiwei , Mo Xuming 
Published: March 2021

Abstract
Background
Little is known about the effects of environmental cobalt exposure on insulin resistance (IR) in the general adult population. We investigated the association between cobalt concentration and IR.

Methods
A total of 1281 subjects aged more than 20 years with complete blood cobalt data were identified from the National Health and Nutrition Examination Survey (NHANES) 2015–2016 cycle. Blood cobalt levels were analyzed for their association with IR among all populations and subgroups by sex. Regression coefficients and 95% confidence intervals (CIs) of blood cobalt concentrations in association with fasting glucose, insulin and homeostatic model assessment of insulin resistance (HOMA-IR) were estimated using multivariate linear regression after adjusting for age, sex, ethnicity, alcohol consumption, body mass index, education level, and household income. A multivariate generalized linear regression analysis was further carried out to explore the association between cobalt exposure and IR.

Results
A negative association between blood cobalt concentration (coefficient = − 0.125, 95% CI − 0.234, − 0.015; P = 0.026) and HOMA-IR in female adults in the age- and sex-adjusted model was observed. However, no associations with HOMA-IR, fasting glucose, or insulin were found in the overall population. In the generalized linear models, participants with the lowest cobalt levels had a 2.74% (95% CI 0.04%, 5.50%) increase in HOMA-IR (P for trend = 0.031) compared with subjects with the highest cobalt levels. Restricted cubic spline regression suggested that a non-linear relationship may exist between blood cobalt and HOMA-IR.

Conclusions
These results provide epidemiological evidence that low levels of blood cobalt are negatively associated with HOMA-IR in female adults.
A cross-country study of skills and unemployment flows
Authors: Stijepic Damir 
Published: March 2021

AbstractUsing an international survey that directly assesses the cognitive skills of the adult population, I study the relation between skills and unemployment flows across 37 countries. Depending on the specifically assessed domain, I document that skills have an unconditional correlation with the log-risk-ratio of exiting to entering unemployment of 0.65–0.68 across the advanced and skill-abundant countries in the sample. The relation is remarkably robust and it is unlikely to be due to reverse causality. I do not find evidence that this positive relation extends to the seven relatively less advanced and less skill-abundant countries in the sample: Peru, Ecuador, Indonesia, Mexico, Chile, Turkey and Kazakhstan.
Lidocaine combined with magnesium sulfate preserved hemodynamic stability during general anesthesia without prolonging neuromuscular blockade: a randomized, double-blind, controlled trial
Authors: Paula-Garcia Waynice N , Oliveira-Paula Gustavo H , de Boer Hans Donald , Garcia Luis Vicente 
Published: March 2021

Abstract
Background
Lidocaine and magnesium sulfate have become increasingly utilized in general anesthesia. The present study evaluated the effects of these drugs, isolated or combined, on hemodynamic parameters as well as on the cisatracurium-induced neuromuscular blockade (NMB).

Methods
At a university hospital, 64 patients, ASA physical status I and II, undergoing elective surgery with similar pain stimuli were randomly assigned to four groups. Patients received a bolus of lidocaine and magnesium sulfate before the tracheal intubation and a continuous infusion during the operation as follows: 3 mg.kg− 1 and 3 mg.kg− 1.h− 1 (lidocaine - L group), 40 mg.kg− 1 and 20 mg.kg− 1.h− 1 (magnesium - M group), equal doses of both drugs (magnesium plus lidocaine - ML group), and an equivalent volume of isotonic solution (control - C group). Hemodynamic parameters and neuromuscular blockade features were continuously monitored until spontaneous recovery of the train of four (TOF) ratio (TOFR > 0.9).

Results
The magnesium sulfate significantly prolonged all NMB recovery features, without changing the speed of onset of cisatracurium. The addition of lidocaine to Magnesium Sulfate did not influence the cisatracurium neuromuscular blockade. A similar finding was observed when this drug was used alone, with a significantly smaller fluctuation of mean arterial pressure (MAP) and heart rate (HR) measures during anesthesia induction and maintenance. Interestingly, the percentage of patients who achieved a TOFR of 90% without reaching T1–95% was higher in the M and ML groups. Than in the C and L groups. There were no adverse events reported in this study.

Conclusion
Intravenous lidocaine plays a significant role in the hemodynamic stability of patients under general anesthesia without exerting any additional impact on the NMB, even combined with magnesium sulfate. Aside from prolonging all NMB recovery characteristics without altering the onset speed, magnesium sulfate enhances the TOF recovery rate without T1 recovery. Our findings may aid clinical decisions involving the use of these drugs by encouraging their association in multimodal anesthesia or other therapeutic purposes.

Trial registration
NCT02483611 (registration date: 06-29-2015).