bluuebunny/crossref_metadata_2025_split huggingface dataset:
Smart interfaces to assist the operator in the context of industry 4.0 with a 5S human-centric approach
Authors: Rojas Mario , Maldonado-Romo Javier , Mendez Juana Isabel , Ponce Pedro , Molina Arturo 
Published: December 2024

Abstract
This paper explores the integration of haptic gloves and virtual reality (VR) environments to enhance industrial training and operational efficiency within the framework of Industry 4.0 and Industry 5.0. It examines the alignment of these technologies with the Sustainable Development Goals (SDGs), mainly focusing on SDG 8 (Decent Work and Economic Growth) and SDG 9 (Industry, Innovation, and Infrastructure). By incorporating a human-centric approach, the study leverages haptic gloves to provide realistic feedback and immersive experiences in virtual training environments. The gloves enable intuitive interaction, enhancing the training efficacy and reducing real-world operational errors. Using the 5S principles—Social, Sustainable, Sensing, Smart, and Safe—this research evaluates the system’s impact across various dimensions. The findings indicate significant improvements in user comfort, productivity, and overall well-being, alongside enhanced sustainability and operational efficiency. However, challenges related to realistic hand-object interactions and algorithmic enhancements were identified. The study underscores the importance of continuous improvement and cross-disciplinary collaboration to advance the usability and effectiveness of these technologies. Future research should focus on customization, AI-driven adaptability, sustainability, real-world scalability, and comprehensive impact assessment to further develop smart interfaces in industrial settings. This integration represents a transformative opportunity to enhance workplace safety, skills development, and contribute to global sustainable development goals.
Exploring Coping Strategies Among Ukrainian Refugee Adolescents
Authors: Chabursky Sophia , Walper Sabine 
Published: December 2024

Abstract: Theoretical Background: The war in Ukraine has led to the displacement of countless families, subjecting children and adolescents to significant stressors such as trauma from the conflict, loss, and the challenges of adapting to a new culture upon resettlement. To deal with these stressors, they develop and employ a variety of coping strategies. Aim: This study aimed to identify and explore the innate coping strategies employed by Ukrainian refugee adolescents as they adapt to life in Germany after displacement in order to better understand how to support them during such a difficult time of crisis. Method: We conducted 25 semi-structured interviews with Ukrainian refugees aged 12 – 18 years, covering topics from their escape from Ukraine to their everyday life in Germany. The data were holistically analyzed using Braun and Clarke’s thematic analysis method. The themes identified, representing the coping strategies employed by the refugees, were examined in light of Lazarus and Folkman’s psychological stress and coping theory, which distinguishes between emotion-focused and problem-focused coping. Results: The analysis revealed a multifaceted approach to coping, encompassing both emotion-focused and problem-focused strategies. Many participants prioritized educational pursuits and future planning, adopting a proactive approach to their new challenges. Maintaining familiar routines from their life in Ukraine provided a sense of continuity and stability amid change. Emotional regulation, facilitated by creative activities and social support, emerged as a critical coping theme. Building and maintaining social connections were key for emotional support and integration. Some adolescents coped by distancing themselves from distressing aspects of their past or present, while others engaged in reflecting on past experiences, sometimes finding solace and at other times experiencing sorrow. Notably, despite facing adversities, a sense of optimism was observed in some adolescents, indicating an adaptive and resilient mindset. Discussion and Conclusion: The study underscores the importance of holistic support for refugee children and adolescents that acknowledges and works with their innate coping strategies. It highlights the complexity of the refugee experience, where growth and struggle coexist, and the need for tailored interventions to support young refugees in not only immediate challenges but also in long-term mental health.
Past and Future Climate‐Driven Changes of Agricultural Land in Central Europe
Authors: Torbenson M. C. A. , Esper J. , Brázdil R. , Büntgen U. , Olesen J. E. , Semarádová D. , Vlach M. , Urban O. , Balek J. , Kolář T. , Rybníček M. , Pernicová N. , Reinig F. , Martinez del Castillo E. , Jones P. D. , Trnka M. 
Published: December 2024

AbstractEurope is expected to experience major climatic shifts during the 21st century but the impact on agricultural productivity from such changes is uncertain. Here, we combine proxy, instrumental, and model data to assess interannual to multi‐centennial changes in central European agroclimate over the past 2,000 years and projections into the near future. Whereas early 21st century conditions are rare but not fully unprecedented, more than half of the area that was considered highly productive throughout the Common Era in central Europe currently falls outside of that definition. This trend will likely continue as even the most conservative climate projections push central Europe outside the range of past natural variability of changes to agroclimatic zones. Reconstructed extremes prior to the instrumental record align well with contemporary documentary records of societal upheaval. Forecasted changes to the main agroclimatic drivers require substantial adaptation in land use and agricultural management strategies of considerable costs.
Adiabatic and Non‐Adiabatic Electron Heating at Quasi‐Perpendicular Collisionless Shocks
Authors: Lalti A. , Khotyaintsev Yu. V. , Graham D. B. 
Published: December 2024

AbstractThe relative contribution of adiabatic and non‐adiabatic processes to electron heating across collisionless shocks remains an open question. We analyze the evolution of suprathermal electrons across 310 quasi‐perpendicular shocks with Alfvénic Mach numbers in the normal‐incidence frame ranging from 1.7 to 48, using in situ measurements of Earth's bow shock by the Magnetospheric Multiscale (MMS) spacecraft. We introduce a novel non‐adiabaticity measure derived from the electron distribution function and based on Liouville's theorem. Our results reveal, for the first time, that the electron heating mechanism is governed by the Alfvénic Mach number in the de Hoffman‐Teller frame , with a transition from predominantly adiabatic to non‐adiabatic heating occurring at . Furthermore, by examining the spectral index of the suprathermal electron distribution, we find that for shocks exhibiting dominant non‐adiabatic electron dynamics, the observed electron heating is consistent with the predictions of the stochastic shock drift acceleration (SSDA) mechanism.
Mars Nightside Ionospheric Response During the Disappearing Solar Wind Event: First Results
Authors: Ram L. , Rout D. , Sarkhel S. 
Published: December 2024

AbstractWe investigated, for the first time, the impact of the disappearing solar wind (DSW) event [26–28 December 2022] on the deep nightside ionospheric species using MAVEN data sets. An enhanced plasma density has been observed in the Martian nightside ionosphere during extreme low solar wind density and pressure periods. At a given altitude, the electron density surged by ∼2.5 times, while for ions (NO+, O2+, CO2+, C+, N+, O+, and OH+), it enhanced by > 10 times, respectively, compared to their typical average quiet‐time periods. This investigation suggests that an upward ionospheric expansion likely took place in a direct consequence to the contrasting low dynamic/magnetic pressure and relatively higher nightside ionospheric pressure (by 1–2 orders) causing an increased ionospheric density. Moreover, the day‐to‐night plasma transport may also be a contributing factor to the increased plasma density. Thus, this study offers a new insight about planetary atmosphere/ionosphere during extreme quiescent solar wind periods.
Experimental Evidence for Reaction‐Induced Weakening of (Carbonated) Serpentinite Fault Gouges
Authors: Eberhard L. , Niemeijer A. R. , Plümper O. 
Published: December 2024

AbstractThe seismic potential of faults depends on the local mineralogy and can change upon mineral reactions. We conducted friction experiments on serpentinite, carbonate and carbonated serpentinite fault gouges at temperatures from 400°C to 630°C, under 100 MPa effective normal stress and fluid saturated conditions. Pure serpentinite fault gouges exhibited unstable slip with significant strain‐hardening. Carbonate‐bearing serpentinite fault gouges showed stable sliding at temperatures <500°C, but displayed unstable stick‐slip behavior and strong strain weakening at temperatures ≥500°C. Microstructural analyses revealed localization and the formation of olivine and pyroxene from devolatilization reactions at temperatures ≥500°C. The degree of devolatilization increased near major slip planes and was enhanced by higher temperature and carbonate content, as shown by three‐dimensional micro‐computer tomography analyses. Nano‐scale transmission electron microscopy analyses revealed the absence of hydrous and carbonate phases along major slip planes. We attribute the strong weakening and unstable slip behavior in carbonated serpentinite fault gouges to the formation of nano‐sized anhydrous phases of olivine and pyroxene along the slip plane. Our results indicate that serpentinized fault zones may experience seismic event nucleation at temperatures approaching the thermodynamic stability limit of serpentine. This suggests that the absence of seismic events cannot exclusively be attributed to serpentinization. The formation of carbonates, through replacive and additive carbonation, can explain aseismic deformation in transform faults, but at elevated temperatures, devolatilization reactions in carbonated serpentinites cause strong localization and strain weakening, accompanied by laboratory seismicity.
Surface Wave Development and Ambient Sound in the Ocean
Authors: Thomson Jim , Yang Jie , Taylor Robert , Rainville E. J. , Zeiden Kristin , Rainville Luc , Brenner Samuel , Ballard Megan , Cronin Meghan F. 
Published: December 2024

AbstractWind, wave, and acoustic observations are used to test a scaling for ambient sound levels in the ocean that is based on wind speed and the degree of surface wave development (at a given wind speed). The focus of this study is acoustic frequencies in the range 1–20 kHz, for which sound is generated by the bubbles injected during surface wave breaking. Traditionally, ambient sound spectra in this frequency range are scaled by wind speed alone. In this study, we investigate a secondary dependence on surface wave development. For any given wind‐speed, ambient sound levels are separated into conditions in which waves are 1) actively developing or 2) fully developed. Wave development is quantified using the non‐dimensional wave height, a metric commonly used to analyze fetch or duration limitations in wave growth. This simple metric is applicable in both coastal and open ocean environments. Use of the wave development metric to scale sound spectra is first motivated with observations from a brief case study near the island of Jan Mayen (Norwegian Sea), then robustly tested with long time‐series observations of winds and waves at Ocean Station Papa (North Pacific Ocean). When waves are actively developing, ambient sound levels are elevated 2–3 dB across the 1–20 kHz frequency range. This result is discussed in the context of sound generation during wave breaking and sound attenuation by persistent bubble layers.
Enhancing Short‐Term Wind Speed Prediction Capability of Numerical Weather Prediction Through Machine Learning Methods
Authors: Zeng Zhaoliang , Wu Honglei , Liu Zhaohua , Zhao Linna , Liang Zhaoming , Liang Zhehao , Wang Yaqiang 
Published: December 2024

AbstractAccurate forecasting of wind speed is essential for daily life and social production. While numerical weather prediction products are widely used, they rely on global data and mathematical models to solve atmospheric dynamics' equations, often failing to capture localized micrometeorological phenomena accurately. Factors such as surface conditions, land‐sea differences, and topography, particularly in coastal areas, further impact the accuracy of wind speed forecasts. This study presents a new method to enhance short‐term wind speed forecasting along China's coast by incorporating local and neighborhood spatiotemporal information. The approach integrates meteorological data from adjacent grid points as new inputs in the LightGBM, CatBoost, and XGBoost algorithms. Stacking ensemble technique is then employed to effectively combine with the aforementioned foundational models. Two sets of experiments are conducted: Experiments 1 exclude surrounding information, while Experiments 2 include it. Each set consists of five experiment groups: annual, spring, summer, autumn, and winter. Within each group, four models are tested: XGBoost, LightGBM, CatBoost, and stacking. Results show that incorporating surrounding site information improves forecast accuracy. In all five groups with added surrounding site information, the stacking model performs best. Compared to ECMWF forecast data, the stacking model improves wind speed forecast accuracy from 53.3%, 50.9%, 55.2%, 53.0%, and 54.0% to 77.2%, 73.1%, 76.7%, 78.2%, and 77.1%, respectively. These findings demonstrate the potential effectiveness of the proposed method for improving short‐term wind speed forecasts in China's coastal areas.
Spatially and Temporally Detailed Water and Carbon Footprints of U.S. Electricity Generation and Use
Authors: Siddik Md Abu Bakar , Shehabi Arman , Rao Prakash , Marston Landon T. 
Published: December 2024

AbstractElectricity generation in the United States entails significant water usage and greenhouse gas emissions. However, accurately estimating these impacts is complex due to the intricate nature of the electric grid and the dynamic electricity mix. Existing methods to estimate the environmental consequences of electricity use often generalize across large regions, neglecting spatial and temporal variations in water usage and emissions. Consequently, electric grid dynamics, such as temporal fluctuations in renewable energy resources, are often overlooked in efforts to mitigate environmental impacts. The U.S. Department of Energy (DOE) has initiated the development of resilient energyshed management systems, requiring detailed information on the local electricity mix and its environmental impacts. This study supports DOE's goal by incorporating geographic and temporal variations in the electricity mix of the local electric grid to better understand the environmental impacts of electricity end users. We offer hourly estimates of the U.S. electricity mix, detailing fuel types, water withdrawal intensity, and water consumption intensity for each grid balancing authority through our publicly accessible tool, the Water Integrated Mapping of Power and Carbon Tracker (Water IMPACT). While our primary focus is on evaluating water intensity factors, our dataset and programming scripts for historical and real‐time analysis also include evaluations of carbon dioxide (equivalence) intensity within the same modeling framework. This integrated approach offers a comprehensive understanding of the environmental footprint associated with electricity generation and use, enabling informed decision‐making to effectively reduce Scope 2 water usage and emissions.
Sphk1/S1P pathway promotes blood-brain barrier breakdown after intracerebral hemorrhage through inducing Nlrp3-mediated endothelial cell pyroptosis
Authors: Feng Mengzhao , An Yuan , Qin Qi , Fong Iat-Hang , Zhang Kaiyuan , Wang Fang , Song Dengpan , Li Mengyuan , Yu Min , Yeh Chi-Tai , Chang Junlei , Guo Fuyou 
Published: December 2024

AbstractIntracerebral hemorrhage (ICH) is a severe stroke subtype with high mortality and limited therapeutic options. The blood-brain barrier (BBB) breakdown post-ICH exacerbates secondary brain injury, highlighting the need for targeted therapies to preserve the BBB integrity. We aim to investigate the role of the Sphk1/S1P pathway in BBB breakdown following ICH and to evaluate the therapeutic potential of Sphk1 inhibition in mitigating this breakdown. Using a combination of human patient samples, mouse models of ICH, and in vitro cellular assays, we assessed the expression levels of Sphk1/S1P after ICH and changes of the BBB after ICH. The Sphk1 inhibitor PF543 and siRNAs were utilized to explore the pathway’s impact on BBB integrity and the underlying mechanisms. The results indicate significant upregulation of Sphk1/S1P in the peri-hematomal brain tissue after ICH, which correlates with increased BBB leakage. Pharmacological inhibition of Sphk1 with PF543 attenuates BBB leakage, reduces hematoma volume, and improves neurological outcomes in mice. At the molecular and ultrastructural level, Sphk1 inhibition protects the BBB integrity by preserving tight junction proteins and suppressing endothelial transcytosis. Furthermore, mechanistic studies reveal that Sphk1 promotes Nlrp3-mediated pyroptosis of brain endothelial cells through the ERK1/2 signaling pathway. Taken together, the Sphk1/S1P pathway plays a critical role in ICH-induced BBB breakdown, and its inhibition represents a promising therapeutic strategy for ICH management.
CARM1-mediated OGT arginine methylation promotes non-small cell lung cancer glycolysis by stabilizing OGT
Authors: Lin Luyao , Yuan Qingxia , Gu Jiayi , Bai Guangyu , Cong Xianling , Hu Qianying , Hou Jingyao , Jin Xin , Liu Xiangxiang , Huang Baiqu , Zhang Yu , Lu Jun 
Published: December 2024

AbstractO-GlcNAcylation catalyzed by O-GlcNAc transferase (OGT) plays an important role in the regulation of tumor glycolysis. However, the mechanism underlying OGT regulation remains largely unknown. Here, we showed that coactivator associated arginine methyltransferase 1 (CARM1) sensed changes of extracellular glucose levels in non-small cell lung cancer (NSCLC) cells. Increased glucose upregulated CARM1 and OGT. CARM1 methylated OGT at arginine 348, promoting its stability through binding of the deubiquitinase USP9X. The arginine methylation of OGT increased global O-GlcNAcylation levels, thereby promoting glycolysis in NSCLC cells. OGT arginine methylation also upregulated c-Myc expression and promoted the proliferation of NSCLC cells in vitro and in vivo. Consistently, OGT expression was positively correlated with CARM1 in human NSCLC samples. The present findings shed light on the mechanism underlying the stabilization of OGT by arginine methylation in response to changes of glucose concentration. The study also clarified the role of the CARM1-USP9X-OGT axis in glycolysis in NSCLC, providing a potential new target or therapeutic strategy in NSCLC.
Chromosome architecture and low cohesion bias acrocentric chromosomes towards aneuploidy during mammalian meiosis
Authors: Bellou Eirini , Zielinska Agata P. , Mönnich Eike Urs , Schweizer Nina , Politi Antonio Z. , Wellecke Antonina , Sibold Claus , Tandler-Schneider Andreas , Schuh Melina 
Published: December 2024

AbstractAneuploidy in eggs is a leading cause of miscarriages or viable developmental syndromes. Aneuploidy rates differ between individual chromosomes. For instance, chromosome 21 frequently missegregates, resulting in Down Syndrome. What causes chromosome-specific aneuploidy in meiosis is unclear. Chromosome 21 belongs to the class of acrocentric chromosomes, whose centromeres are located close to the chromosome end, resulting in one long and one short chromosome arm. We demonstrate that acrocentric chromosomes are generally more often aneuploid than metacentric chromosomes in porcine eggs. Kinetochores of acrocentric chromosomes are often partially covered by the short chromosome arm during meiosis I in human and porcine oocytes and orient less efficiently toward the spindle poles. These partially covered kinetochores are more likely to be incorrectly attached to the spindle. Additionally, sister chromatids of acrocentric chromosomes are held together by lower levels of cohesin, making them more vulnerable to age-dependent cohesin loss. Chromosome architecture and low cohesion therefore bias acrocentric chromosomes toward aneuploidy during mammalian meiosis.
VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier
Authors: Martikainen Miika , Lugano Roberta , Pietilä Ilkka , Brosch Sofie , Cabrolier Camille , Sivaramakrishnan Aishwarya , Ramachandran Mohanraj , Yu Di , Dimberg Anna , Essand Magnus 
Published: December 2024

AbstractSemliki Forest virus (SFV) is a neuropathogenic alphavirus which is of interest both as a model neurotropic alphavirus and as an oncolytic virus with proven potency in preclinical cancer models. In laboratory mice, peripherally administered SFV infiltrates the central nervous system (CNS) and causes encephalitis of varying severity. The route of SFV CNS entrance is poorly understood but has been considered to occur through the blood-brain barrier. Here we show that neuroinvasion of intravenously administered SFV is strictly dependent on very-low-density-lipoprotein receptor (VLDLR) which acts as an entry receptor for SFV. Moreover, SFV primarily enters the CNS through the blood-cerebrospinal fluid (B-CSF) barrier via infecting choroid plexus epithelial cells which show distinctly high expression of VLDLR. This is the first indication of neurotropic alphavirus utilizing choroid plexus for CNS entry, and VLDLR playing a specific and crucial role for mediating SFV entry through this pathway.
Stable isotope evidence for pre-colonial maize agriculture and animal management in the Bolivian Amazon
Authors: Hermenegildo Tiago , Prümers Heiko , Jaimes Betancourt Carla , Roberts Patrick , O’Connell Tamsin C. 
Published: December 2024

AbstractOver the past decade, multidisciplinary research has seen the Amazon Basin go from a context perceived as unfavourable for food production and large-scale human societies to one of ‘garden cities’, domestication, and anthropogenically influenced forests and soils. Nevertheless, direct insights into human interactions with particular crops and especially animals remain scarce across this vast area. Here we present new stable carbon and nitrogen isotope data from 86 human and 68 animal remains dating between ce ~700 and 1400 from the Llanos de Mojos, Bolivia. We show evidence of human reliance on maize agriculture in the earliest phases before a reduction in the dietary importance of this crop between ce 1100 and 1400. We also provide evidence that muscovy ducks (Cairina moschata), the only known domesticated vertebrate in the South American lowlands, had substantial maize intake suggesting intentional feeding, or even their domestication, from as early as ce 800. Our data provide insights into human interactions with Amazonian ecosystems, including direct evidence for human management of animals in pre-colonial contexts, further enriching our understanding of human history in what was once considered a ‘counterfeit paradise’.