bluuebunny/crossref_metadata_2025_split huggingface dataset:
Revisiting the Post-glitch Relaxation of the 2000 Vela Glitch with the Neutron Star Equation of States in the Brueckner and Relativistic Brueckner Theories
Authors: Shang Xinle , Li Ang 
Published: December 2021

Abstract
We revisit the short-term post-glitch relaxation of the Vela 2000 glitch in the simple two-component model of the pulsar glitch by making use of the latest realistic equations of states from the microscopic Brueckner and the relativistic Brueckner theories for neutron stars, which can reconcile with the available astrophysical constraints. We show that to fit both the glitch size and the post-glitch jumps in frequency derivatives approximately 1 minute after the glitch, the mass of the Vela pulsar is necessarily small, and there may be demands for a stiff equation of state (which results in a typical stellar radius larger than ∼12.5 km) and a strong suppression of the pairing gap in the nuclear medium. We discuss the implications of this result on the understanding of pulsar glitches.
Spatial Variation in Temperature and Density in the IC 63 PDR from H2 Spectroscopy
Authors: Soam Archana , Andersson B-G , Karoly Janik , DeWitt Curtis , Richter Matthew 
Published: December 2021

Abstract
We have measured the gas temperature in the IC 63 photodissociation region (PDR) using the S(1) and S(5) pure rotation lines of molecular hydrogen with SOFIA/EXES. We divide the PDR into three regions for analysis based on the illumination from γ Cas: sunny, ridge, and shady. Constructing rotation diagrams for the different regions, we obtain temperatures of T
ex =

562

−
43

+
52

K toward the ridge and T
ex =

495

−
25

+
28

K in the shady side. The H2 emission was not detected on the sunny side of the ridge, likely due to the photodissociation of H2 in this gas. Our temperature values are lower than the value of T
ex = 685 ± 68 K using the S(1), S(3), and S(5) pure rotation lines, derived by Thi et al. using lower spatial resolution ISO-SWS data at a different location of the IC 63 PDR. This difference indicates that the PDR is inhomogeneous and illustrates the need for high-resolution mapping of such regions to fully understand their physics. The detection of a temperature gradient correlated with the extinction into the cloud, points to the ability of using H2 pure rotational line spectroscopy to map the gas temperature on small scales. We used a PDR model to estimate the FUV radiation and corresponding gas densities in IC 63. Our results shows the capability of SOFIA/EXES to resolve and provide detailed information on the temperature in such regions.
Édifier le monument du roi en 1547
Authors: Chiron Pascale 
Published: December 2021

En 1547 parut un recueil contenant un récit du rituel funèbre et les « deux sermons funèbres » prononcés par Pierre Du Chastel lors des obsèques de François I er . La dramaturgie visuelle et sonore y édifie un monument du prince à valeur parénétique ; les oraisons, jouant de leur lieu d’énonciation originel, inscrivent le decorum royal dans la langue. Mais ce monument du prince qui devrait être incontestable trouve des résistances qui illustrent la place de l’auteur et de son éditeur dans cet acte d’édification.
Diderot et les Projets de monument pour le dauphin
Authors: Cammagre Geneviève 
Published: December 2021

Pour Diderot, sans avoir la technique de l’artiste, l’homme de lettres peut concevoir l’idée organisatrice d’une œuvre. Quand Cochin lui commande au début de 1766 un projet de tombeau pour le dauphin, il en conçoit cinq, décrits dans deux lettres à Sophie Volland. L’article étudie ses variations sur le thème imposé de la réunion future des époux : de la scène de tendresse conjugale jusqu’au réalisme macabre. Ses projets n’ont pas été retenus mais ont eu une influence sur l’art funéraire à la fin du siècle.
Le philosophe au temple de Mémoire. Poèmes-monuments et inscriptions en vers à la gloire de Descartes
Authors: Chométy Philippe 
Published: December 2021

La poésie fixe à jamais dans les mémoires l’image des grands hommes. Elle contribue du XVII e au XVIII e siècle à la monumentalisation de Descartes. Épitaphes gravées, médailles, livres imprimés, estampes, lettres manuscrites, crâne : tous les supports sont bons, en vers français, latins ou néerlandais, pour servir à sa renommée. S’il s’est créé un mythe national autour de Descartes, c’est aussi parce que sa représentation en héros de la philosophie reçoit une empreinte poétique profonde.
Un déficit de représentation ? Sentiment de représentation et participation électorale dans une ancienne municipalité communiste
Authors: Hadj Belgacem Samir 
Published: December 2021

Cet article envisage le lien entre représentation et participation électorale pour les habitant·es des cités de logement social. Au-delà de leur seule perception, il étudie l’articulation entre la participation et les liens avec les représentant·es. À partir d’une enquête socio-historique au Blanc-Mesnil, ville anciennement communiste, il formule plusieurs hypothèses concernant la faiblesse du sentiment de représentation politique qui prédomine parmi les habitant·es des cités de logement social. L’enquête rend compte de la montée de l’abstention au cours des années 1980. La contestation de la représentation par les élu·es de la majorité de gauche se déploie durant les années 1990-2010. Des porte-parole émergent alors pour tenter de représenter les habitant·es des cités au sein de l’exécutif municipal. Leurs difficultés, tant à se faire reconnaître comme des interlocuteurs et interlocutrices légitimes qu’à participer à la liste de gauche, renforcent la défiance vis-à-vis des élu·es de la majorité. Ces porte-parole et candidat·es à la représentation (presque exclusivement masculins) participent activement à la construction du sentiment de représentation parmi les habitant·es. Dans le cadre public, ils insistent en particulier sur l’importance de la représentation sociale et territoriale et sur la connaissance des difficultés des habitant·es. Cependant, en variant les situations d’énonciation, l’identification aux représentant·es peut aussi prendre une dimension ethno-raciale, qui demeure largement circonscrite au « texte caché », car jugée illégitime.
La guerre civile espagnole et Hollywood : l’impossible transgression
Authors: Elefteriou-Perrin Véronique 
Published: December 2021

La dimension internationale des hostilités qui débutent en Espagne en juillet 1936 ainsi que leur couverture journalistique et documentaire massive, l’implication d’une partie des citoyens des États-Unis mais aussi la popularité des intrigues filmiques liées aux guerres font de ce conflit un motif attractif pour les studios cinématographiques américains. Comment toutefois rendre compte des enjeux idéologiques du conflit et des camps en présence alors même que s’opposent les prises de position et les formes d’action tant dans la société américaine que dans l’industrie du film ? Le pragmatisme commercial et la politique de censure qui régissent les studios, associés dans ce moment particulier de l’histoire mondiale aux réalités propres à l’opinion publique des États-Unis – isolationnisme, refus de tout bellicisme –, font obstacle aux projets hollywoodiens de documentation visuelle de la tragédie espagnole en cours.
Le roman sentimental Regency , entre continuités et ruptures (2000-2020)
Authors: Boussahba-Bravard Myriam 
Published: December 2021

La romance sentimentale produite aux États-Unis participe aujourd’hui à l’industrie du divertissement, marché mondial soutenu par la traduction. Vendu ou emprunté en édition papier ou numérique, le roman d’amour est téléchargé sur des liseuses, tablettes, téléphones et ordinateurs. Les intrigues de la romance historique sont souvent ancrées dans l’histoire anglaise et écossaise, surtout la Régence. Ainsi, l’attitude des personnages féminins et masculins face aux injonctions sociales de genre et de classe apporte une valeur « exotique » qui résonne chez les consommatrices-électrices jouissant de l’égalité formelle entre les sexes dans les démocraties occidentales. Cette consommation massive du fait historique, authentique, questionne néanmoins l’historicité de l’entreprise fictionnelle.
Multiparametric Magnetic Resonance Imaging, 68Ga Prostate-Specific Membrane Antigen Positron Emission Tomography–Computed Tomography, and Respective Quantitative Parameters in Detection and Localization of Clinically Significant Prostate Cancer in Intermediate- and High-Risk Group Patients
Authors: Kubihal Vijay , Sharma Sanjay , Kumar Rakesh , Seth Amlesh , Kumar Rajeev , Kaushal Seema , Sarangi Jayati , Gupta Ravikant , Das Chandan Jyoti 
Published: December 2021

Objectives:
The objective of this study was to evaluate the diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) and 68Ga prostate-specific membrane antigen positron emission tomography–computed tomography (PSMA PET-CT) and respective quantitative parameters (Ktrans – influx rate contrast, Kep – efflux rate constant, ADC – apparent diffusion coefficient, and SUVmax ratio – prostate SUVmax to background SUVmax ratio) in detection and localization of clinically significant prostate cancer (CSPCa) in D’Amico intermediate- and high-risk group patients (prostate-specific antigen [PSA] >10 ng/ml).

Methodology:
The study included thirty-three consecutive adult men with serum prostate specific antigen >10ng/ml, and systematic 12 core prostate biopsy proven prostate cancer. All the 33 patients, were evaluated with mpMRI, and 68Ga PSMA PET-CT. The biopsy specimens and imaging were evaluated for 12 sectors per prostate by a predetermined scheme.

Results:
MpMRI Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) score ≥3 showed higher sensitivity than 68Ga PSMA PET-CT (96.3% vs. 82.4%), with similar specificity (54.5% vs. 54.5%) (n = 33 patients, 396 sectors). Combined use of MRI and 68Ga PSMA PET-CT in parallel increased sensitivity (99.5%) and NPV (98.7%) for detection of CSPCa and combined use of MRI and 68Ga PSMA PET-CT in series increased specificity (71.8%) and PPV (71.5%) (n = 33 patients, 396 sectors). ADC showed a strong negative correlation with Gleason score (r = −0.77), and the highest discriminative ability for detection and localization of CSPCa (area under curve [AUC]: 0.91), followed by Ktrans (r = 0.74; AUC: 0.89), PI-RADS (0.73; 0.86), SUVmax ratio (0.49; 0.74), and Kep (0.24; 0.66).

Conclusion:
MpMRI PI-RADS v2 score and 68Ga PSMA PET-CT (individually as well as in combination) are reliable tool for detection and localization of CSPCa. Quantitative MRI and 68Ga PSMA PET-CT parameters have potential to predict Gleason score and detect CSPCa.
Utility and feasibility of a six-color multiparametric flow cytometry for measurable residual disease analysis in plasma cell myeloma in resource-limited settings with 5-year survival data
Authors: Sharma Praveen , Singh Sachdeva Man Updesh , Varma Neelam , Bose Parveen , Aggarwal Ritu , Malhotra Pankaj 
Published: December 2021

Introduction:
Treatment of multiple myeloma (MM) has evolved over decades with the introduction of novel therapeutic strategies. Response rates has significantly improved; however, there is a need for more sensitive techniques to study the residual disease other than conventional means. We evaluated the feasibility and utility of a two-tube six color multiparametric flow cytometry (MFC) assay for measurable residual disease (MRD) detection in MM patients on treatment.

Methodology:
Pretitrated cocktails containing antibodies against CD38, CD138, CD45, CD19, CD56, CD81, CD27, and cytoplasmic kappa and lambda light chains were used in the combination of two tubes and were acquired on a flow cytometer. Limit of detection was determined through dilution and spiking experiments with a limit of 0.01%.

Results:
Of the 62 patients screened, 58 patients were included in the final study cohort (day 100 postautologous stem cell transplant and at the end of induction chemotherapy). Twenty-eight patients (48%) revealed the presence of MRD in bone marrow on MFC (median = 0.12, range = 0.01–5.89%). Out of 28 MFC-MRD positive patients, only 16 patients showed M band on immunofixation-electrophoresis (IFE) (MRD+/IFE+, 57%), and rest of them were IFE negative (MRD+/IFE-, 42%). Patients with MRD positive status at the end of induction chemotherapy or day 100 posttransplant had an inferior overall survival (P = 0.009) and progression-free survival (P = 0.0002) than those with MRD negativity.

Conclusion:
We have demonstrated the impact of MRD testing in MM using MFC with a long follow-up data, suggesting its routine incorporation in monitoring the disease independent of the immunofixation status.
Fluorescent spectroscopic assessment before and after radiation treatment in oral cavity cancer and its clinical correlation
Authors: Akram Mohammad , Afrose Ruquiya , Katiyar R. K. 
Published: December 2021

Background:
Biochemical changes in irradiated malignant tissue lead to altered autofluorophores status which should be different for cancerous tissue (residual/recurrence) and irradiated normal tissue. If this irradiated tissue is examined through fluorescent spectroscopy, we can find the spectroscopic changes occurring after the completion of treatment which can be helpful in evaluating treatment response.

Methods:
Punch biopsy sample was examined through fluorescent spectroscopy in oral cavity cancer patients before and after definitive radiation treatment. The change in spectroscopic pattern before and after radiation treatment was recorded and assessed.

Results:
Final analysis was done in 36 samples. In irradiated tissue, it has been observed that there was increase in the intensity of collagen fluorescence. It was found that the Half width half maximum (HWHM) is more in case of preirradiated sample. The decrease in the HWHM in case of irradiated sample shows the decrease in the number of cells (cell density as compared to that in preirradiated sample). These spectral findings are well-explained pathophysiologically and clinically as amount of collagen are increased in irradiated tissues due to loss of cancerous cells and regeneration of collagen cross-links (fibrosis) and reproduction of normal tissue as a response to radiation treatment.

Conclusion:
After thorough study in a large number of samples, we may be able in the future to grade the alteration in fluorescence of collagen obtained after radiation treatment in terms of complete, partial, or no response.
Effect of high-dose intravenous ascorbic acid on cancer patients following ketogenic diet
Authors: Sebastian Stelvin , Paul Aby , Joby Joel , Saijan Sanjo , Vilapurathu Jobin Kunjumon 
Published: December 2021

Background:
The role of ascorbic acid in cancer therapy is mainly due to its structural similarity with glucose. When supplemented intravenously in high dose, ascorbic acid can get into the cancer cells and induce apoptosis by causing mitochondrial damage.

Aim:
The aim was to study the efficacy of high-dose intravenous (IV) ascorbic acid as monotherapy in cancer patients following ketogenic diet and its role in improving the quality of life.

Results:
C-reactive protein (CRP) and erythrocyte sedimentation rates (ESRs) were considered as parameters to determine the efficacy of the treatment, and substantial decrease in both the levels was observed within 1-week treatment. CRP levels declined from 3.1946 ± 3.2508 mg/L to 1.0606 ± 0.6706 mg/L (P = 2.27E-10), whereas ESR levels declined from 64.1333 ± 38.8253 mm/h to 31.6 ± 16.5520 mm/h (P = 0.0041). A decline in these parameters shows the association of ascorbic acid in reducing the inflammatory response in cancer. The renal effect of ascorbic acid was also studied by analyzing the creatinine level pre- and postascorbic acid treatment sessions, and it raised from 0.8526 ± 0.22904 to 1.1666 ± 0.2894 mg/dL (P = 1.18E-14). This showed the renal impact of ascorbic acid.

Conclusion:
The study highlighted the clinical benefit of IV ascorbic acid in the reduction of inflammatory response in cancer patients. The renal adverse events associated with ascorbic acid alarm the use with caution and therapeutic drug monitoring for ascorbic acid.
Active Surveillance of Adverse Events Following Coronavirus Disease 2019 Immunization in the Elderly Population
Authors: Tiwari Surya Pratap Singh , Anil Bhandari , Monika Rathore , Lokendra Sharma , Aditya Sharma , Smita Jain , Madhav Agarwal 
Published: December 2021

Background:
Vaccine against coronavirus disease 2019 (COVID-19) was rolled out in India to prevent the infection caused by severe acute respiratory syndrome coronavirus 2. We aimed at investigating the adverse events following immunization (AEFI) associated with the first dose of Covishield (ChAdOx1 nCoV-19) vaccine in the elderly population (60 and above).

Methodology:
An observational study, conducted among 463 vaccinated individuals at multiple community health centers in Jaipur, of AEFIs associated with the first dose of Covishield vaccine. We investigated these AEFIs through telephonic interviews, using pharmacovigilance per forma provided from the Indian Pharmacopoeia Commission, Ghaziabad.

Results:
Four hundred and sixty-three people responded to the telephone survey. About 7.7% (36/463) of the respondents experienced AEFIs. Of these, commonly reported systemic AEFI were fever (47.2%), fatigue (38.8%), dizziness (5.5%), and diarrhea (2.7%), and local AEFI were injection site soreness (27.7%) and itching with rash (2.7%) AEFI reported in the age group (60–70) was higher (8.7%, 26/297) than those above 70 (6.2%, 10/166). Females (9.9%, 20/202) were associated with higher AEFI than males (6.1%, 16/261). More than one-third (43.8%, 203/463, P = 0.001) were hesitant before vaccination. Respondents in the age group of 60–70 years (55.2%, 164/297) were more hesitant than those above 70 (23.4%, 39/166). There is no association between gender and AEFI status and age group and respondent's AEFI.

Conclusion:
Only 7.7% of the respondents experienced AEFIs associated with ChAdOx1 nCoV-19, though all were mild and self-limiting. There were no serious events requiring hospitalization, and most AEFIs improved within few days. Vaccine hesitancy among 43.8% of the respondents could be attributed to the unscientific information on social media.
Cultural Competence Assessment in a Health-Care University
Authors: Balachandran Parvathy , Krishna Devika Maya , Janakiram Chandrashekar 
Published: December 2021

Introduction:
Cultural competence of health-care professionals has a vital role in health-care system. The first step toward this orientation is the assessment of cultural competence level of clinical graduate students.

Objective:
The objective of the study was to assess the cultural competence of clinical graduate students of various courses in a health-care university, Kerala, India.

Methods:
A cross-sectional study was conducted among 398 clinical graduate students in a health-care university in Kerala, India. The self-administered questionnaire had 27 items adapted from various validated scales. Data analysis was done by the analysis of variance (ANOVA) using SPSS software (version 23). P < 0.05 was considered statistically significant.

Results:
The overall mean of the responses ranged from 2.81 (confidence interval [CI]: 2.70–2.93) to 4.50 (CI: 4.43–4.57). ANOVA revealed statistically significant differences between the courses in competencies related to specific competencies.

Conclusion:
Our findings suggest that cultural competence of health-care graduates can be improved by incorporating cultural competence training in the curriculum.
Relationship between Emotional Intelligence and Aggression Among Nursing Students in a Tertiary Institute
Authors: Gijwani Deeksha , Mathur Anmol , Batra Manu , Sharma Aditi 
Published: December 2021

Background:
Working with emotions is an important aspect of the nurse–patient relationship: the nurse will better manage his/her own emotions, and will also influence patient's emotions on investigations, treatments, fears, vision about disease, etc., Aggression is one of the important factors that significantly affect the performance of an individual.

Aim:
The aim of this study was to identify the level of emotional intelligence (EI) and aggression among nursing students and to assess its correlations with sociodemographic variables.

Materials and Methods:
A cross sectional study was done among 242 nursing students of various nursing colleges of Sri Ganganagar, Rajasthan. Data collection was done using two questionnaires one for emotional intelligence and another for aggression level. The results were determined using the mean, standard deviation, T test and Pearson's correlation coefficient with level of significance was set at P < 0.05.

Results:
There is a nonsignificant negative relationship of verbal aggression (r = −0.0192) with EI. Higher aggression was seen in male participants in the age group of 18–21 years and in the 1st year of nursing students (P ≤ 0.01).

Conclusion:
Males were more aggressive whereas females were found to be more emotionally intelligent in the current study.
Estimation of Fluoride Level in Drinking Water Samples of Raipur District, Chhattisgarh
Authors: Jain Anubhuti , Parakh Abhinav , Yunus G. Y. , Naveen N. , Jain Kamlesh Kumar , Agrawal Ruchi 
Published: December 2021

Background:
The fluoride intake in the general population derives chiefly from drinking water and dietary sources. The presence of fluoride in groundwater for drinking purposes may be beneficial or detrimental depending on its concentration and the amount ingested.

Objective:
The objective of the study was to estimate the concentration of fluoride in drinking water sources of Raipur district.

Methodology:
A descriptive cross-sectional study was carried out for fluoride mapping of Raipur district. Samples of drinking water were collected from 50 different sites of 20 villages. The concentration of fluoride in drinking water was analyzed using ion-selective electrode method.

Results:
In all the water samples analyzed, there was the presence of trace amount of fluoride, which ranged from 0.2 ± 1.22 ppm with the mean concentration of 0.411 ± 0.180 ppm.

Conclusion:
Fluoride levels in groundwater were in trace quantity and well below the optimal level of fluoride necessary for caries prevention.
Qualitative and Quantitative Evaluation of Bacterial Contamination of Toothbrushes Kept in Different Sanitary Settings
Authors: Thakur Meenakshi , Mittal Sudhir , Sharma Amit Kumar , Sharma Devender Kumar , Gupta Kamal K , Pathania Vasundhara 
Published: December 2021

Background:
Oral health is an integral part of general health and toothbrushes are the most commonly used oral hygiene aid. Unfortunately, proper care of toothbrush is often neglected and is kept in bathrooms which are a good place to harbor millions of microorganisms.

Aim:
To assess the bacterial contamination of toothbrushes for Streptococcus mutans, Staphylococcus aureus, Candida albicans, and Lactobacillus when kept in different sanitary settings before and after the use of disinfectant.

Materials and Methods:
A total of 60 volunteers were randomly selected between the age of 6–16 years. Toothbrushes were grouped into two categories: Group 1: Outside the bathroom. Group 2: Within the bathroom with attached toilet. Group 2 was further divided into two subgroups: Group 2 (i): Kept individually in separate containers. Group 2 (ii) kept with that of family members and siblings within the same container. The present study was carried for 3 months in two phases with the same participants both before and after the use of disinfectant.

Results:
Microbial contamination was highest in Streptococcus and least in Lactobacillus before and after the use of disinfectant when toothbrushes were kept outside the bathroom and microbial contamination was similar in both Streptococcus and Lacctobacilus when kept inside the bathroom with attached toilet in separate container and same container both before and after the use of disinfectant.

Conclusion:
A high level of pathogenic microorganisms were seen in toothbrushes kept in the bathroom for 3 months which were reduced by dipping them in 0.12-% chlorhexidine gluconate.