bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced Manufacturing Execution System “MES” Through a Smart Vision System
Authors: El Zant Chawki , Charrier Quentin , Benfriha Khaled , Le Men Patrick 
Published: April 2021

AbstractThe level of industrial performance is a vital issue for any company wishing to develop and acquire more market share. This article presents a novel approach to integrate intelligent visual inspection into “MES” control systems in order to gain performance. The idea is to adapt an intelligent image processing system via in-situ cameras to monitor the production system. The images are thus analyzed in real time via machine learning interpreting the visualized scene and interacting with some features of the MES system, such as maintenance, quality control, security, operations, etc. This novel technological brick, combined with the flexibility of production, contributes to optimizing the system in terms of autonomy and responsiveness to detect anomalies, already encountered, or even new ones. This smart visual inspection system is considered as a Cyber Physical System CPS brick integrated to the manufacturing system which will be considered an edge computing node in the final architecture of the platform. This smart CPS represents the 1st level of calculation and analysis in real time due to embedded intelligence. Cloud computing will be a perspective for us, which will represent the 2nd level of computation, in deferred time, in order to analyze the new anomalies encountered and identify potential solutions to integrate into MES. Ultimately, this approach strengthens the robustness of the control systems and increases the overall performance of industrial production.
Semantic Enrichment of 3D Models Based on Ontology Integration
Authors: Nzetchou Stéphane , Durupt Alexandre , Eynard Benoit , Remy Sébastien 
Published: April 2021

AbstractThe rise of new technologies has led to a growth in the number of 3D models. They can come from various source, hence they are heterogeneous and complex. The level of 3D data access is often a function of the user’s expertise since the 3D data are often registered to different file formats. Some file formats do not show the data tree, as IGES. For using information inside a 3D model, that does not show a data tree, each company adopts his own system that will allow him to access easily to 3D model in order to exploit the hidden knowledge within the models. In this article, we are going to speak about technologies that helps user to exploit and knowledge coming from different file formats. In addition, we are going to present a system named VAQUERO that uses ontology to access, store and share knowledge coming from 3D models.
Design for Manufacturing and Assembly: A Method for Rules Classification
Authors: Favi Claudio , Mandolini Marco , Campi Federico , Cicconi Paolo , Raffaeli Roberto , Germani Michele 
Published: April 2021

AbstractThe paper provides a method to acquire, process, and represent DfMA rules to help designers and engineers in the development of mechanical products compliant with manufacturing and assembly technology. This research work wants to define a general method able to link DfMA design guidelines (knowledge engineering) with geometrical product features that are available by the investigation of the 3D model. Numerical parameters of design features are related to design guidelines for the identification of manufacturing and assembly issues within the analysis of the 3D model.
Generation of Entrepreneurship Environments for New Product Development
Authors: Martin-Doñate Cristina , Lucena-Muñoz Fermín , García-Cabrera Lina Guadalupe , Mercado-Colmenero Jorge Manuel 
Published: April 2021

AbstractThe economic environment demands companies to be able of innovating and presenting new products and technologies. However, current industrial environments are composed of big established companies, small or medium family businesses and regional clusters. This business map does not comply with the dynamism required for detecting needs and proposals in form of new products that meet the current customer requirements. The creation of start-ups in the field of engineering is considered as a possibility to cover a growing market in designing high technological products. However, despite the importance and economic impact of the start-ups for less industrialized environments the courses in the engineering field do not include activities that contextualize theoretical knowledge and entrepreneurship. The paper presents the results of creating an entrepreneurial environment focused on the student as entrepreneurial unit. In this context, a series of new activities based on new design proposals have been developed on the basis of new technical solutions for industrial companies. The new designs have been presented as minimum viable products. The technical knowledge required for making the new designs has been complemented with entrepreneurial training. The results show an increase in students' willingness to create small companies based in new products as an employment option at the end of their studies.
Multicriteria Decision Making Methods in Engineering Design: An Application on Medical Devices
Authors: Renzi Cristina , Leali Francesco 
Published: April 2021

AbstractThe design of medical devices is challenging, due to strict geometry specifications and criteria belonging to several disciplines. The aim of this paper is to provide a design methodology which seems to lack in the literature of design of biomedical devices. In particular, the case study proposed in this paper concerns with the design of Bone-Biopsy (BB) needle devices. Following the design process of Pahl and Beitz, a functional analysis is carried out, to point out the interfaces between parts of existing BB needles. A morphology matrix is used to generate alternatives for the cannula holder, the core part of the product. Generated alternatives have been ranked and scored by means of the Pugh’s Controlled Convergence method according to the decision makers' opinions. In this work, the design peculiarities related to the BB needles which have been pointed out could be extended for guiding the design of other biomedical devices.
Smart Tightening Development for Aeronautical Bolted Assemblies in an Industry 4.0
Authors: Foissac Charly , Daidie Alain , Segonds Stephane , Chirol Clément 
Published: April 2021

AbstractSmart tightening development is part of the Industry 4.0 transformation with the introduction of smart tools, and preload in bolted assemblies is of major interest in today’s aircraft manufacturing process. So far, it has been difficult to estimate the importance of each parameter for tightening process quality, mainly because of the large number of combinations and configurations that exist.The present work aims at evaluating the effects and the interactions between different parameters that have to be taken in consideration in future torquing strategy. Many experimental tests have been conducted on an Automatica test bench using a Taguchi strategy and an analysis of the first main results is now presented, highlighting the complexity of the phenomena studied.All these points will help us to better understand tightening, so as to improve performance during installation, maintenance and repair.
Cold Working Process on Hard Metal Stacked Assembly
Authors: Pichon Guillaume , Daidie Alain , Fau Adeline , Chirol Clément , Benaben Audrey 
Published: April 2021

AbstractDesigned for aeronautical and automotive applications, the split sleeve cold expansion process is used to improve the fatigue life of bolted metallic parts. Although its application has been well tested on aluminum assemblies, hard metal applications are still being studied. This paper presents experimental results of double bolt joint assemblies under double shear fatigue tests after stacked split sleeve cold expansion. The behaviors of two sizes of assemblies with different degrees of expansion are investigated. S-N curves are the main indicators of this study but thermal aspects are also investigated to observe fretting in the specimens as bolts are preloaded. Bolt tension is a major parameter in assembly regarding fatigue life. Interference between those two phenomena is at the heart of this paper. The first results show that stacked cold expansion has a negative effect on mechanical performances, as it deteriorates the fatigue life of the assembly. However, an examination of these results provides a coherent explanation for the loss of performance that occurs.
Numerical Simulation and Experimentation of Additive Manufacturing Processes with Polyurethane Foams
Authors: Paquet Elodie , Le Loch Sébastien , Furet Benoit , Bernard Alain , Garnier Sébastien 
Published: April 2021

AbstractFoam Additive Manufacturing (FAM) is the additive manufacturing process allowing parts to be obtained by depositing layers of polyurethane foam using a high-pressure machine. This inexpensive technology allows large parts to be produced in a reduced time. However, the quality of the parts produced by the FAM technique is greatly affected by the various thermal phenomena present during manufacturing and by the geometrical deviations of the layers due to the expansion of the PU foam. Numerical simulation remains an effective analytical tool for studying these phenomena. The aim of this work is to build a geometric and thermal model predictive of the FAM process by the finite element method, the final objective of which is to provide temperature maps throughout the manufacturing process and also to choose the best 3D printing strategy to have a model with constant cords and the smallest possible form deviation. The proposed model and the various simulation techniques used are detailed in this article. This model is developed under the finite element code Rem3D, and validated by experimental tests carried out on a FAM machinery or a robot, an example of which is detailed in this article.
How Human Rights Cross-Pollinate and Take Root: Local Governments and Refugees in Turkey
Authors: Durmuş Elif 
Published: April 2021

AbstractThe human rights regime—as law, institutions and practice—has been facing criticism for decades regarding its effectiveness, particularly in terms of unsatisfactory overall implementation and the failure to protect the most vulnerable who do not enjoy the protection of their States: refugees. Turkey is the country hosting the largest refugee population, with around four million at the end of May 2020 (https://www.unhcr.org/tr/wp-content/uploads/sites/14/2020/06/UNHCR-Turkey-Operational-Update-May-2020.pdf). As an administratively centralised country, Turkey’s migration policy is implemented by central government agencies, but this has not proved sufficient to guarantee the human rights of refugees on the ground. Meanwhile, in connection with urbanisation, decentralisation and globalisation, local governments around the world are receiving increasing attention from migration studies, political science, law, sociology and anthropology. In human rights scholarship, the localisation of human rights and the potential role of local governments have been presented as ways to counter the shortcomings in the effectiveness of the human rights regime and discourse. While local governments may have much untapped potential, a thorough analysis of the inequalities between local governments in terms of access to resources and opportunities is essential. The Turkish local governments which form the basis of this research, operate in a context of legal ambiguity concerning their competences and obligations in the area of migration. They also have to deal with large differences when it comes to resources and workload. In practice, therefore, there is extreme divergence amongst municipalities in the extent to which they engage with refugee policies. This chapter seeks to answer the questionwhy and how certain local governments in Turkey come to proactively engage in policy-making that improves the realisation of refugees’ rights. Exploratory grounded field research among Turkish local governments reveals four main factors that enable and facilitate the engagement of local governments in refugee policies: (1) the capacity of and institutionalisation in local governments; (2) the dissemination of practices and norms surrounding good local migration and rights-based governance through networks; (3) the availability of cooperation and coordination with other actors in the field, and (4) political will. Collectively, these factors illustrate how a new norm—the norm that local governments can and ought to engage in policy-making improving the rights of refugees—is cross-pollinating and taking root among Turkish local governments. This understanding will provide valuable insights into how norms are developed, travel and are institutionalised within social and institutional networks, and how differences in access, capacity, political and cooperative opportunities may facilitate and obscure the path to policies improving human rights on the ground.
Human Rights Localisation and Individual Agency: From ‘Hobby of the Few’ to the Few Behind the Hobby
Authors: Sabchev Tihomir , Miellet Sara , Durmuş Elif 
Published: April 2021

AbstractHuman rights have been facing criticism on many fronts, including the challenges of the “enforcement gap” and the “citizenship gap”, laying bare the shortcomings with regard to the implementation of human rights law as well as regarding its protection of highly vulnerable groups such as refugees. Research on the effectiveness of human rights, the “localisation” of human rights through invocations and practices on the ground, the increased engagement of local authorities with human rights, are all responses to such challenges to some degree. Based on empirical research conducted within municipalities in four countries, this chapter focuses on a missing piece of the puzzle in terms of conceptual and empirical research: the role of “individual agency”. We adopt a socio-legal perspective on human rights and demonstrate that individual agency can make an important contribution to the effective implementation of human rights in the field of migration governance. Behind the black box of the state and local authorities, we find individuals who use human rights—as law, practice and discourse—in local policymaking, in circumstances where invoking human rights is not self-explanatory. Finally, we put forward the notion that reasons such as individual background, motivations, and interactions between individuals influence municipal officials’ engagement with human rights, and we reflect on the conceptual and practical implications that result from this.
G1-phase progression in pluripotent stem cells
Authors: ter Huurne Menno , Stunnenberg Hendrik G. 
Published: April 2021

AbstractDuring early embryonic development both the rapid increase in cell number and the expression of genes that control developmental decisions are tightly regulated. Accumulating evidence has indicated that these two seemingly independent processes are mechanistically intertwined. The picture that emerges from studies on the cell cycle of embryonic stem cells is one in which proteins that promote cell cycle progression prevent differentiation and vice versa. Here, we review which transcription factors and signalling pathways play a role in both maintenance of pluripotency as well as cell cycle progression. We will not only describe the mechanism behind their function but also discuss the role of these regulators in different states of mouse pluripotency. Finally, we elaborate on how canonical cell cycle regulators impact on the molecular networks that control the maintenance of pluripotency and lineage specification.
Wie gut ist das Wissen über sexuell übertragbare Infektionen in Deutschland?
Authors: Matthiesen Silja , von Rüden Ursula , Dekker Arne , Briken Peer , Cerwenka Susanne , Fedorowicz Claudia , Wiessner Christian 
Published: April 2021

Zusammenfassung
Hintergrund
Sexuell übertragbare Infektionen (STI) sind ein relevanter Risikofaktor für die sexuelle Gesundheit des Einzelnen und der Bevölkerung. Für eine zielgruppenspezifische Präventionsarbeit ist der Wissensstand zu STI in verschiedenen Bevölkerungsgruppen daher von besonderem Interesse.

Ziel
Ziel der vorliegenden Arbeit ist es, den Wissensstand zu neun STI in der deutschen Bevölkerung zu analysieren. Dafür werden Zusammenhänge mit soziodemografischen Variablen, sexualitätsbezogenen Merkmalen sowie der subjektiven Zufriedenheit mit dem Informationsstand untersucht.

Methode
Die GeSiD-Studie „Gesundheit und Sexualität in Deutschland“ erhob von 4955 Personen per Face-to-Face-Interview repräsentative quantitative Daten zum Wissensstand zu STI. Als Auswahlverfahren wurde eine zweifache Zufallsstichprobe gezogen. Dafür wurden zunächst 200 Sample Points (Gemeinden) in ganz Deutschland regional proportional ausgewählt. Anschließend wurde eine Zufallsstichprobe von Adressen über die jeweiligen Einwohnermeldeämter gezogen. Die Teilnahmequote betrug 30,2 %; das Durchschnittsalter lag bei 46,3 Jahren.

Ergebnisse
Wissen über HIV/Aids war in allen Altersgruppen weit verbreitet. Andere STI waren deutlich weniger bekannt. Besonders wenig informiert zeigten sich Ältere und Befragte mit niedrigem Bildungsstand, regionaler sozialer Benachteiligung sowie mit Migrationshintergrund. Eine höhere Anzahl von SexualpartnerInnen hing mit einem besseren Wissensstand zusammen. Gut informiert zeigten sich Personen, die sich nicht als heterosexuell beschreiben, sowie Personen, die schon einmal an einer STI erkrankt waren.

Fazit
Heterosexuelle Erwachsene in Deutschland sind unzureichend über STI informiert. Zielgruppenspezifische Anstrengungen zur Verbesserung des Wissens über STI sind nötig, um sexuelles Risikoverhalten zu vermindern und die Inanspruchnahme von Präventionsangeboten zu verbessern.
The role of (dynamic) capabilities in the transformation of a multi-organizational setting
Authors: Paavola Lauri 
Published: April 2021

AbstractThis paper analyzes the role of dynamic capabilities in the transformation of a multi-organizational setting. I conduct an embedded multi-case study in which the cases represent critical transformational events in the history of a shopping center. The five critical transformational events, which have exerted substantial influence on the organizations operating in the context, are concerned with the construction of new premises, modernization of existing premises, and the introduction of new services. I analyze and classify related (dynamic) capabilities of individual organizations, resulting in aggregated outcomes that determine the evolution of the entity. Applying an abductive case research strategy, I then generate five distinct theoretical results on the effects and the interconnectedness of the multi-organizational context, the individual organizations, and their dynamic capabilities.
Characterizing growth instability: new evidence on unit roots and structural breaks in countries’ long run trajectories
Authors: Russo Emanuele , Foster-McGregor Neil 
Published: April 2021

AbstractIn this paper we investigate whether long run time series of income per capita are better described by a trend-stationary model with few structural changes or by unit root processes in which permanent stochastic shocks are responsible for the observed growth discontinuities. For a group of advanced and developing countries in the Maddison database, we employ a unit root test that allows for an unspecified number of breaks under the alternative hypothesis (up to some ex ante determined maximum). Monte Carlo simulations studying the finite sample properties of the test are reported and discussed. When compared with previous findings in the literature, our results show less evidence against the unit root hypothesis. We find even fewer rejections when relaxing the assumption of Gaussian shocks. Our results are broadly consistent with the implications of evolutionary macro models which posit frequent growth shifts and fat-tailed distribution of aggregate shocks.
Suspect screening and targeted analysis of acyl coenzyme A thioesters in bacterial cultures using a high-resolution tribrid mass spectrometer
Authors: Cakić Nevenka , Kopke Bernd , Rabus Ralf , Wilkes Heinz 
Published: April 2021

AbstractAnalysis of acyl coenzyme A thioesters (acyl-CoAs) is crucial in the investigation of a wide range of biochemical reactions and paves the way to fully understand the concerned metabolic pathways and their superimposed networks. We developed two methods for suspect screening of acyl-CoAs in bacterial cultures using a high-resolution Orbitrap Fusion tribrid mass spectrometer. The methods rely on specific fragmentation patterns of the target compounds, which originate from the coenzyme A moiety. They make use of the formation of the adenosine 3′,5′-diphosphate key fragment (m/z 428.0365) and the neutral loss of the adenosine 3′-phosphate-5′-diphosphate moiety (506.9952) as preselection criteria for the detection of acyl-CoAs. These characteristic ions are generated either by an optimised in-source fragmentation in a full scan Orbitrap measurement or by optimised HCD fragmentation. Additionally, five different filters are included in the design of method. Finally, data-dependent MS/MS experiments on specifically preselected precursor ions are performed. The utility of the methods is demonstrated by analysing cultures of the denitrifying betaproteobacterium “Aromatoleum” sp. strain HxN1 anaerobically grown with hexanoate. We detected 35 acyl-CoAs in total and identified 24 of them by comparison with reference standards, including all 9 acyl-CoA intermediates expected to occur in the degradation pathway of hexanoate. The identification of additional acyl-CoAs provides insight into further metabolic processes occurring in this bacterium. The sensitivity of the method described allows detecting acyl-CoAs present in biological samples in highly variable abundances.
Solution to the Quantum Symmetric Simple Exclusion Process: The Continuous Case
Authors: Bernard Denis , Jin Tony 
Published: April 2021

AbstractThe quantum symmetric simple exclusion process (Q-SSEP) is a model for quantum stochastic dynamics of fermions hopping along the edges of a graph with Brownian noisy amplitudes and driven out-of-equilibrium by injection-extraction processes at a few vertices. We present a solution for the invariant probability measure of the one dimensional Q-SSEP in the infinite size limit by constructing the steady correlation functions of the system density matrix and quantum expectation values. These correlation functions code for a rich structure of fluctuating quantum correlations and coherences. Although our construction does not rely on the standard techniques from the theory of integrable systems, it is based on a remarkable interplay between the permutation groups and polynomials. We incidentally point out a possible combinatorial interpretation of the Q-SSEP correlation functions via a surprising connexion with geometric combinatorics and the associahedron polytopes.