bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of portable air filtration on reducing indoor aerosol counts: preclinical observational trials
Authors: Lee Jung Hoon , Rounds Max , McGain Forbes , Schofield Robyn , Skidmore Grant , Wadlow Imogen , Kevin Kevin , Stevens Ashley , Marshall Caroline , Irving Lou , Kainer Marion , Buising Kirsty , Monty Jason 
Published: April 2021

AbstractObjectiveTo assess the effectiveness of aerosol filtration by portable air cleaning devices with high efficiency particulate air (HEPA) filters used in addition to standard building heating ventilation and air-conditioning (HVAC).MethodsTest rooms, including a hospital single-patient room, were filled with test aerosol to simulate aerosol movement. Aerosol counts were measured over time with various portable air cleaning devices and room ventilation systems to quantify the aerosol concentration reduction rate and overall clearance rate.ResultsPortable air cleaners were very effective in removing aerosols, especially for the devices with high flow rate. In a small control room, the aerosols were cleared 4 to 5 times faster with portable air cleaners than the room with HVAC alone. A single bed hospital room equipped with an excellent ventilation rate (∼ 14 air changes per hour) can clear the aerosols in 20 minutes. However, with the addition of two air cleaners, the clearance time became 3 times faster (in 6 minutes and 30 seconds).ConclusionsPortable air cleaning devices with HEPA filtration were highly effective at removing aerosols. To clear aerosols (above 90% clearance) in under 10 minutes requires around 25 air changes per hour; readily feasible with air cleaners. Inexpensive portable air cleaning devices should be considered for small and enclosed spaces in health care settings such as inpatient rooms, personal protective equipment donning/doffing stations, and staff tea rooms. Portable air cleaners are particularly important where there is limited ability to reduce aerosol transmission with building HVAC ventilation.
Interfacing Live Cells with Surfaces: A Concurrent Control Technique for Quantifying Surface Ligand Activity
Authors: Robitaille Michael C. , Christodoulides Joseph A. , Calhoun Patrick , Byers Jeff M. , Raphael Marc P. 
Published: April 2021

AbstractSurface ligand activity is a key design parameter for successfully interfacing surfaces with cells - whether in the context ofin vitroinvestigations for understanding cellular signaling pathways or more applied applications in drug delivery and medical implants. Unlike other crucial surface parameters, such as stiffness and roughness, surface ligand activity currently lacks a standardized measurement approach that can be readily paired with live cell investigations. To fill this void, we have developed a concurrent control technique for characterizingin vitroligand surface activity. Pairs of gold-coated glass chips were biofunctionalized with RGD ligand in a parallel workflow: one chip forin vitroapplications and the other for surface plasmon resonance (SPR) based RGD activity characterization. Recombinant αVβ3integrins were injected over the SPR chip surface as mimics of the cellular membrane bound receptors and the resulting binding kinetics parameterized to quantify ligand activity. These activity measurements were correlated with cell morphological features, measured by interfacing MDA-MB-231 cells with thein vitrochip surfaces on the live cell microscope. We show that the SPR concurrent control approach has multiple advantages based on the facts that SPR is a standardized technique and has the sensitivity to measure ligand activity across the most relevant range of extracellular surface densities. Furthermore, by pairing both SPR andin vitroapproaches, a comparison of the results can provide biological insights into the nature of cellular adhesion and dynamics.
Mega- and meta-analyses of fecal metagenomic studies assessing response to immune checkpoint inhibitors
Authors: Heirali Alya , Chen Bo , Wong Matthew , Schneeberger Pierre HH , Rey Victor , Spreafico Anna , Xu Wei , Coburn Bryan A. 
Published: April 2021

AbstractPurposeGut microbiota have been associated with response to immune checkpoint inhibitors (ICI) including anti-PD-1 and anti-CTLA-4 antibodies. However, inter-study difference in design, patient cohorts and data analysis pose challenges to identifying species consistently associated with response to ICI or lack thereof.Experimental DesignWe uniformly processed and analyzed data from three studies of microbial metagenomes in cancer immunotherapy response (four distinct data sets) to identify species consistently associated with response or non-response (n=190 patient samples). Metagenomic data were processed and analyzed using Metaphlan v2.0. Meta- and mega-analyses were performed using a two-part modelling approach of species present in at least 20% of samples to account for both prevalence and relative abundance differences between responders/non-responders.ResultsMeta- and mega-analyses identified five species that were concordantly significantly different between responders and non-responders. Amongst them,Bacteroides thetaiotaomicronandClostridium bolteaerelative abundance (RA) were independently predictive of non-response to immunotherapy when data sets were combined and analyzed using mega-analyses (AUC 0.59 95% CI 0.51-0.68 and AUC 0.61 95% CI 0.52-0.69, respectively).ConclusionsMeta- and mega-analysis of published metagenomic studies identified bacterial species both positively and negatively associated with immunotherapy responsiveness across four published cohorts.
Finding trafficked children through crowdsourcing: a usability evaluation
Authors: Goh Dion Hoe-Lian , Lee Chei Sian , Zhou Quan , Guo Hang 
Published: April 2021

PurposeThe purpose of this paper is to investigate how perceived usability and user characteristics influence the intention to use a crowdsourcing application for finding potentially trafficked children. As part of this effort, the authors also attempt to uncover the usability concerns surrounding the use of this application.Design/methodology/approachThe authors first describe Zhongxun, which is the application used in the present paper. Next, they conducted a survey eliciting usability perceptions of Zhongxun. A total of 287 participants were recruited for the survey which used constructs adapted from the Computer System Usability Questionnaire as well as various demographic variables. Hierarchical regression analysis was used to ascertain factors influencing intention to use Zhongxun. Participants' qualitative feedback was also analyzed to derive themes pertaining to areas of improvement.FindingsThe results showed that system usefulness was the factor that most positively influenced intention to use Zhongxun, followed by information quality and interface quality. Interestingly, a higher level of education was negatively associated with intention to use the application. Qualitative feedback suggested various ways of improving Zhongxun's functionality. Participants recommended the incorporation of gamification mechanisms as a new feature of the application. Cultivating awareness of Zhongxun was also suggested as a means to attract new users.Practical implicationsThe work can help inform the design of crowdsourcing applications for finding missing and potentially trafficked children, as well as similar systems. Implications include the need for simplicity of design, communication strategies to attract new and retain existing users, and instilling confidence in the quality of crowdsourced contributions.Originality/valuePrior research in evaluating the usability of crowdsourcing applications has been performed but not in the context of finding missing and potentially trafficked children. The task of finding such children is markedly different from previous usage contexts and could impact perceptions of usability and usefulness. Hence, the present study attempts to plug this research gap.
Examining drivers and outcomes of social media brand engagement
Authors: Leckie Civilai , Dwivedi Abhishek , Johnson Lester 
Published: April 2021

PurposeThis study empirically examines a set of drivers (i.e. social media involvement, self-brand congruence, firm image and relationship age) of consumers’ social media brand engagement (SMBE), which subsequently influences consumer outcomes (i.e. consumer satisfaction, brand trust and perceived value).Design/methodology/approachData were collected using a self-administered online survey of 340 social media users. Structural equation modelling was employed to test the conceptual model.FindingsFindings indicate that social media involvement, self-brand congruence and firm image are significant drivers of SMBE, while relationship age is not. SMBE subsequently impacts consumer satisfaction, brand trust and perceived value.Research limitations/implicationsThis study contains some limitations associated with cross-sectional research. It does not investigate consumer engagement with other entities (e.g. other commercial brands) through the use of social media.Practical implicationsThese findings call for marketing managers and social media brand managers to pay attention and invest resources in the significant drivers of SMBE. They also provide insights on enhancing SMBE to strengthen consumer–brand relationships.Originality/valueBased on consumer–brand relationship marketing and consumer psychology of brands, this study investigates brand-related relational drivers and outcomes of SMBE, thereby deepening understanding of consumer engagement in digital environments.
The synergistic impact of motivations on sustained pro-environmental consumer behaviors: an empirical evidence for single-use plastic products
Authors: Pham Chuong Hong , Nguyen Hung Vu , Le Mai Thi Thu , Do Long Thanh , Nguyen Phuong Thi Tung 
Published: April 2021

PurposeThis paper employed the self-determination theory (SDT) to examine the synergistic impacts of intrinsic, extrinsic and prosocial motivations in promoting sustained pro-environmental consumption behaviors (PECB). To provide evidence for the study’s theoretical framework, the authors focus on the behavior of reducing single-use plastics.Design/methodology/approachA mall-intercept survey for consumption of single-use plastic products in three big cities of Vietnam (Hanoi, Da Nang and Ho Chi Minh city) was conducted to test the theoretical framework. In total, 468 consumers completed the questionnaires. Data were analyzed with SPSS and AMOS.FindingsIntrinsic and prosocial motivations are found to be significant predictors of sustained PECB. More importantly, beyond the direct effects of intrinsic and prosocial motivations, the authors also found positive interaction effects between intrinsic and extrinsic motivation and between intrinsic and prosocial motivation on encouraging sustained PECB.Originality/valueThis research offers a new insight for encouraging sustained PECB. Different from the extant perspectives which usually deal with initiating PECB, the authors emphasize sustaining the behavior. Moreover, this research examines the interaction effects between intrinsic and extrinsic motivations and between intrinsic and prosocial motivations in sustaining PECB.
A DfX-based approach for incorporating sustainability in infrastructure project planning
Authors: Marinelli Marina 
Published: April 2021

PurposeThis paper investigates how the “Design for Sustainability” mindset of the manufacturing sector can be effectively transferred in the context of construction and proposes appropriate implementation tools for the promotion of sustainability in infrastructure projects' planning and design.Design/methodology/approachThe Design for Excellence (DfX) approach is first investigated in the context of manufacturing through the review of related literature, and the goals of Design for Sustainability (DfS), in particular, are specified. The suggestions of the literature are used as a basis for the development of the conceptually equivalent goals in the context of infrastructure projects and to highlight the construction management strategies which qualify as potential DfS tools.FindingsThis paper presents how well-known construction planning and management methods, techniques or strategies such as cost–benefit analysis, sustainability-driven procurement, contractors' involvement in design, value-based design, building information modeling (BIM) and buildability review enable the holistic promotion of the triple bottom line in feasibility, design and procurement of infrastructure projects, when combined in the context of an integrated planning approach.Originality/valueThe DfX mindset has very limited presence in the construction literature. This paper attempts to conceptualize its scope in the context of infrastructure projects while putting the multidimensional concept of sustainability as primary planning and design consideration. The proposed planning approach and the systematic mapping of the respective implementation tools can facilitate the decision-makers to achieve the desired sustainability benefits, in line with their priorities.
Exploring the structure and emerging trends of construction health management: a bibliometric review and content analysis
Authors: Liang Huakang , Shi Xiaoxiao 
Published: April 2021

PurposeThe demanding nature of construction industry poses serious health risks to construction workers. In recent years, construction health management (CHM) has gained much attention to ensure a healthier and safer workplace. However, there is still lack of a systematic review to bring together the disaggregated studies and determine the development status of this research field. As essential for addressing health issues in construction industry, a bibliometric and content-based review on of previous CHM studies would be presented in this paper.Design/methodology/approachIn total, 753 journal articles published in Web of Science core collection from 1990 to 2020 were examined using a systematic review. Bibliometric analysis concentrated on the analysis of publication and citation pattern of CHM research while content analysis was employed to identify main health hazards, levels of analysis and topical focuses.FindingsThe results indicated that the USA was the leading country in this research domain. Five health hazards together with 17 research topics at different levels of analysis were classified to allow researchers to track the structure and temporal evolution of the research field. Finally, three emerging trends and a set of research agenda were proposed to guide future research directions.Originality/valueIt is the first to highlight the issues of occupational health management from the perspective of construction workers. It contributes to the field of construction health management by clarifying the knowledge structure, emerging trends and future research directions. It offers valuable guidance and in-depth understanding to researchers, practitioners and policymakers to further promote construction workers' health performance.
Internationalization of higher education in Korea: policy trends toward the pursuit of the SDGs
Authors: Jon Jae-Eun , Yoo Sung-Sang 
Published: April 2021

PurposeThe purpose of this paper is to analyze the policy trends for the internationalization of higher education in Korea, and suggest a future direction toward the pursuit of Sustainable Development Goals (SDGs).Design/methodology/approachThis paper presents a case study of Korea focusing on its internationalization in higher education. In order to analyze the government policy trends and institutional strategies for internationalization, the relevant literature and documents were analyzed.FindingsThe government policy for the internationalization of higher education in Korea has consisted of three stages: first, controlled outbound mobility; second, a major shift and focus on inbound mobility, recently along with intraregional cooperation for both directions of mobility in Asia and third, the beginning of efforts toward the pursuit of the SDGs, which needs to be expanded and systematized further.Originality/valueThis paper shows presents the comprehensive review of internationalization policies in Korean higher education, including the recent programs and changes at both the governmental and institutional levels. There has been a notable lack of discussion on the SDGs in relation to the internationalization of Korean higher education, which is addressed in this paper.
Emergency centre handover from the perspective of prehospital emergency care providers in Johannesburg, South Africa
Authors: Makkink Andrew William , Stein Christopher Owen Alexander , Bruijns Stevan Raynier 
Published: April 2021

PurposeThe purpose of this paper is to describe handover in the emergency centre from the perspective of prehospital emergency care providers in Johannesburg, South Africa. Reference to emergency centre handover from the prehospital perspective will have particular relevance to all deliverers of emergency centre handover.Design/methodology/approachA purposive, cross-sectional design addressed the study aim by using a purpose-designed, validated, paper-based questionnaire to collect data relating to prehospital emergency care personnel's perspectives on emergency centre handover.FindingsThere were 175 completed questionnaires collected from South African prehospital personnel within the Johannesburg area. The response rate was 175/290 or 62%. Training on handover was described as poor. There was a general appreciation of mnemonics and how well they ensured that all relevant information was handed over. However, this was countered by poor familiarity of common mnemonics. Perception of the accuracy of their own and observed prehospital handovers was generally positive. Handover length was generally perceived to be appropriate. The qualification of emergency centre personnel was perceived to impact on how handovers were received.Research limitations/implicationsThe study was limited to one geographical area and did not include all potential participants in the study area. The self-reported data collection meant that there was a risk of self-report bias. These factors may have negatively affected the generalisability of the data.Originality/valueThis paper seeks to describe perceptions related to emergency centre handover from the perspective of prehospital emergency care personnel. In doing so, it is postulated that there is the potential to use these findings to improve certain aspects of emergency centre handover.
Leveraging big data analytics capabilities in making reverse logistics decisions and improving remanufacturing performance
Authors: Bag Surajit , Luthra Sunil , Mangla Sachin Kumar , Kazancoglu Yigit 
Published: April 2021

PurposeThe study investigated the effect of big data analytics capabilities (BDACs) on reverse logistics (strategic and tactical) decisions and finally on remanufacturing performance.Design/methodology/approachThe primary data were collected using a structured questionnaire and an online survey sent to South African manufacturing companies. The data were analysed using partial least squares based structural equation modelling (PLS–SEM) based WarpPLS 6.0 software.FindingsThe results indicate that data generation capabilities (DGCs) have a strong association with strategic reverse logistics decisions (SRLDs). Data integration and management capabilities (DIMCs) show a positive relationship with tactical reverse logistics decisions (TRLDs). Advanced analytics capabilities (AACs), data visualisation capabilities (DVCs) and data-driven culture (DDC) show a positive association with both SRLDs and TRLDs. SRLDs and TRLDs were found to have a positive link with remanufacturing performance.Practical implicationsThe theoretical guided results can help managers to understand the value of big data analytics (BDA) in making better quality judgement of reverse logistics and enhance remanufacturing processes for achieving sustainability.Originality/valueThis research explored the relationship between BDA, reverse logistics decisions and remanufacturing performance. The study was practice oriented, and according to the authors’ knowledge, it is the first study to be conducted in the South African context.
Reducing uncertainties in innovation projects through intra-organisational collaboration: a systematic literature review
Authors: Fanousse Rola Imad , Nakandala Dilupa , Lan Yi-Chen 
Published: April 2021

PurposeThis article provides the first systematic review of literature on effective organisational practices for reducing innovation project uncertainties to promote project performance. Innovation is the lifeblood of organisations, while simultaneously being one of the most challenging processes to manage. This systematic review seeks to examine best practice for reducing uncertainties and thus mitigate the high failure rates in innovation projects.Design/methodology/approachThis paper provides a systematic review of the literature on innovation project management and encourages an understanding of how intra-organisational collaboration reduces uncertainty and thus increases project performance.FindingsBased on an analysis of the systematic literature review findings, the impact of intra-organisational collaboration in reducing uncertainties in innovation projects is uncovered. Three types of project uncertainties were found to be dominant in the context of innovation project management: task, technological and market uncertainties. Five dimensions of intra-organisational collaboration are also identified, namely collaborative relationship, collaborative leadership, communicating and sharing information, trust formation and joint decision-making.Originality/valueThe authors situate five intra-organisational collaboration dimensions as key mechanisms that yield organisational learning as an outcome. On the other hand, they also uncovered that organisational learning is a key enabler in the relationship between intra-organisational collaboration and task, market and technological uncertainties reduction. Therefore, intra-organisational collaboration is identified as a critical practice in enhancing the performance of innovation projects. The study proposes a multi-dimensional conceptual model, providing a mechanism for furthering a research agenda for improving the performance of innovation projects.
Do corporate social responsibility practices affect the relative efficiency of Egyptian conventional and Islamic banks?
Authors: Shahwan Tamer Mohamed , Habib Ahmed Mohamed 
Published: April 2021

PurposeThis study assesses the impact of corporate social responsibility (CSR) practices on the relative efficiency of conventional and Islamic Egyptian banks in the period 2012–2018.Design/methodology/approachA three-stage approach is adopted. First, data envelopment analysis (DEA) is used to assess the relative efficiency of Egyptian banks. Second, a CSR index is designed and used to assess the extent of aggregate CSR practices in Egyptian banks, together with their sub-dimensions. Third, a Tobit regression model is used to examine the impact of CSR on the technical efficiency of these banks.FindingsThere is no statistically significant difference between conventional and Islamic banks as regards their purely technical efficiency. Egyptian banks, on average, have achieved a medium score in their practices of CSR and conventional and Islamic banks have not shown significant differences, except in 2018. Moreover, the aggregate CSR practices positively affect the technical efficiency of Egyptian banks. The practices of the CSR sub-dimensions, apart from the community sub-dimension, also affect the banks' technical efficiency.Practical implicationsThe legislative institutions and the Central Bank should enhance CSR practices in Egyptian banks, particularly the practices related to customers and the community, in order to enhance the purely technical efficiency of these banks.Originality/valueThe paper is original in investigating the impact of CSR on banks' relative efficiency in Egypt.