bluuebunny/crossref_metadata_2025_split huggingface dataset:
Can combined multiparametric magnetic resonance imaging of the prostate and prostate-specific antigen density improve the detection of clinically significant prostate cancer
Authors: Yadav Kuldeep , Sureka Binit , Elhence Poonam , Choudhary Gautam Ram , Pandey Himanshu , Garg Pawan Kumar , Yadav Taruna , Khera Pushpinder Singh 
Published: May 2021

Objective:
The objective of the study was to validate PIRADS v2 on 3T MRI with secondary assessment if combination of the PIRADS v2 and PSA density improves detection of clinically significant prostate cancer.

Materials and Methods:
We conducted a prospective study evaluating 58 patients with PSA value of >4 ng/ml from July 2017 to December 2019. Transrectal ultrasonography (TRUS) guided targeted biopsy was performed via cognitive targeting followed by systemic 12 core biopsy. Two cognitive fusion-targeted biopsy cores were added for each lesion in patients who had suspicious or equivocal lesions on mpMRI. The PI-RADS scoring system version 2.0 (PI-RADS v2) was used to describe the MRI findings.

Results:
Total of 112 lesions of 58 patients were assessed via mpMRI followed by TRUS guided biopsy. A PI-RADS v2 score of ≥4 irrespective of PSA density categories and a PI-RADS v2 score of 3 with PSA density of ≥0.15 ng/mL/cc, yielded the highest overall prostate cancer and clinically significant prostate cancer detection rate. Contrary to, a PI-RADS v2 score of ≤3 and a PSA densitay of <0.15 ng/ mL/mL(low risk group), which yielded no clinically significant prostate cancer.

Conclusion:
Both PIRADS v2 score and PSA density are eminently sensitive and specific in the detection of clinically significant prostate cancers individually. However the combination of PIRADS v2 and PSA density significantly improved the accuracy of clinically significant prostate cancer detection. Patients with combination of PIRADS v2 score3 3 and PSA density3 0.15 ng/ml/cc should undergo prostate biopsy.
Hypofractionated radiotherapy versus conventional radiotherapy in early glottic cancer T1-2N0M0
Authors: Kachhwaha Avni , Jakhar Shankar Lal , Syiem Tanya , Sharma Neeti , Kumar Harvinder Singh , Sharma Ajay 
Published: May 2021

Objective:
Glottic cancer has an excellent probability of cure. The early glottic cancer is usually treated by radiotherapy with different fractionation schedules. The aim of this study was to compare conventional versus hypofractionated radiotherapy with respect to overall survival and disease-free survival.

Materials and Methods:
A total of fifty patients with T1-2N0M0 glottic cancer with no previous treatment history were prospectively randomized into two arms. In Arm A (Study), patients received a total of 55 Gy in 20# at 2.75 Gy/#, 5 days a week. In Arm B (Control), patients received a total of 66 Gy in 33# at 2 Gy/#, 5 days a week. Disease response was evaluated by the WHO criteria at the end of treatment, then at 1, 2, and 3 months to complete their 6-month follow-up. Overall survival and disease-free survival were evaluated at 1, 2, and 3 years.

Results:
Overall, 100% of patients in the study arm and 96% of patients in the control arm had complete response after 6 months. Overall survival rates at 1, 2, and 3 years were 96%, 96%, and 88%, respectively, in the study arm, while in the control arm, these values were 92%, 84%, and 80%, respectively, and the difference was not statistically significant (P > 0.05). Disease-free survival at 3 years was 88% in the study arm and 80% in the control arm.

Conclusion:
The study suggests that hypofractionated regimen may be better in local control and symptomatic relief with the added advantage of shorter treatment time, which offers better patient compliance and advantageous in busy setups where there is heavy patient load.
Utilization of Airlift Fermenters in the Mass Propagation of Pseudomonas and AureobasidiumSpecies for the Bioremediation of Crude Oil Polluted Aquatic Environments
Authors: Ejianreh E.L. , Aransiola E.F. , Adebimpe A.I. , Solomon B.O. 
Published: May 2021

This study involved the design and fabrication of airlift fermenters for the mass propagation of a consortium of three microorganisms (Pseudomonas aeruginosa, Pseudomonas fluorescence and Aureobasidium pullulans). The efficacy of the blend in the bioremediation of simulated crude oil polluted water systems environments was also tested with a view to generating more data on crude oil degrading microorganisms for bioremediation purposes. The organisms were separately grown on a gyratory shaker at 120 rpm and at 30 °C until notable growths were observed. Equal volume of the grown organisms (500 ml) of mixed culture was used as inoculum for the 4.5 L of medium in the 7 L airlift fermenter. Thereafter, this was transferred into the 45 litres medium in the 70 L fermenter until significant growth was observed at room temperature. Culture broths were withdrawn at intervals for the determination of biomass and residual hydrocarbon concentrations. The product from the 70 L fermenter was introduced into simulated polluted water systems from which samples were withdrawn weekly. Analyses for residual hydrocarbon contents were carried out using appropriate analytical techniques. The results showed that 78.5% hydrocarbon removal was observed in the 7 L fermenter after 72 h, while that of the 70 L fermenter was 97.8% after 180 h of fermentation. Polluted water sample treated with the microbes experienced 96.4% removal after 10 weeks of treatment. It was observed further that the application of NPK fertilizer biostimulant aided microbial activities in the removal of petroleum hydrocarbons than urea, cow dung and poultry droppings. The study has demonstrated that effective bioremediation of crude oil polluted water systems could be achieved through the application of biostimulants with mass propagated crude oil degrading organisms using airlift fermenter systems.
Keywords: Pseudomonas aeruginosa; Pseudomonas fluorescence; Aureobasidium pullulans; Airlift fermenter; Bioremediation; Biostimulation; Bioaugmentation.
Phylogenetic analysis of hydrocarbon degrading bacteria associated with crude oil polluted soil from Mesogar community, Delta State, Nigeria
Authors: Olukunle O.F. 
Published: May 2021

This study was carried out to isolate hydrocarbon-degrading bacteria associated with oil polluted soil samples collected from Mesogar community of Delta State, Nigeria. The samples were aseptically collected and the bacteria isolated according to standard microbiological techniques. The isolates with hydrocarbon biodegradative ability were screened on MSM supplemented with 2% crude oil using spectrophotometric method. The amount of crude oil degraded by the highest hydrocarbon degrader was determined using gas chromatographic (GC) assay. A total of seven bacterial isolates were molecularly identified using the 16S rRNA gene sequencing method. The sequences were compared to those deposited in NCBI using the basic local alignment tool (BLAST) algorithm. Phylogenetic analysis of 16S rRNA gene sequences was carried out to determine the evolutionary relationships of the isolated bacterial species. The isolates were identified to have remote similarities with Alcaligenes faecalis SH179a, Alcaligenes faecalis subsp. Phenolicus, Bacillus thuringiensis serovar konkukian, Ochrobactrum anthropi, Alcaligenes faecalis SH179b, Uncultured soil bacterium clone and Alcaligenes faecalis IVN45. Strain OFBR 4 had the highest degrading ability. The use of molecular methods for rapid and accurate detection of diverse strains of hydrocarbon-degraders is of utmost necessity in bioremediation.
Keywords: Phylogenetic analysis, oil polluted soil, biodegradative, hydrocarbon degrader, 16S rRNA gene and crude oil.
AN INSTRUCTIONAL SCENARIO (LESSON PLAN): THE IMPORTANCE OF ARTERIAL PULSE
Authors: Vogiatzaki Eirini , Nikolopoulou Anastasia 
Published: May 2021

<p>This article aims to present a lesson plan entitled: "An instructional scenario: The Importance of Arterial pulse". This teaching plan lasts for one teaching hour. It was carried out with modern educational form through the Cisco WebEx Meetings platform and concerns the course Nursing Theory II for the 3rd Class of Vocational High School (EPAL), specializing in Nursing of the Health, Welfare &amp; Wellness Sector. This lesson plan was implemented in the context of the training of B2 level ICT trainees, organized by the Institute of Educational Policy (IEP) with the co-financing support of Greece and the European Union. The article aims to present a teaching plan so that students can deepen their knowledge in the topic of Vital Signs with emphasis on the importance of arterial pulse. More specifically, students learn to define what an arterial pulse is, to list the points where the arterial pulse is taken, and to state each time the arterial pulse should be taken. The strategy on which it was based is collaborative learning. In particular, through the working groups, the participation and the interaction with the students are reinforced. Students were asked to complete interactive exercises created in the e-me content, then work on a collaborative document (google forms), and at the end of the course fill in a worksheet for feedback.</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0747/a.php" alt="Hit counter" /></p>
The Effect of the Examples Non Examples Learning Model on the Active Learning of PAK of Class VIII Students of SMP Negeri 2 Lumbanjulu, Tobasa Regency, 2019/2020 Academic Year.
Authors: Pakpahan Darma Wati 
Published: May 2021

The research was to know the influence of the Non Examples Examples Learning Model on the Active Learning of Students of Class VIII of SMP Negeri 2 Lumbanjulu, 2019/2020. Research hypothesis is that there is an influence between the Examples non Examples Learning Model on the Active Learning of Students of Class VIII of SMP Negeri 2 Lumbanjulu, 2019/2020 Academic Year. The population is all students in SMP Negeri 2 Lumbanjulu totaling 115 people. Samples were taken 30% from 115 people = 40 people. This study concludes that the influence of the Examples non Examples Learning Model on the Active Learning of PAK of Class VIII Students of SMP Negeri 2 Lumbanjulu 2019/2020 is 32.9%.Keywords: Examples non Examples Learning Model, Student Learning Active Activity
Pengaruh Model Pembelajaran Picture and Picture Terhadap Minat Belajar PAK Siswa Kelas VII SMP Negeri 2 DolokSanggul Tahun Pembelajaran 2019/2020
Authors: Silaen Elfira 
Published: May 2021

The purpose of this study was to determine the effect of Picture and Picture Learning Model on students’ interest in Learning Christian Religion Education of Grade VII in SMP Negeri 2 DolokSanggul Academic Year 2019/2020.The method used in this research is inferential statistical method. The population was all grade VII students of SMP Negeri 2 DolokSanggul Academic Year 2019/2020 with a total of 281 people and a sample of 32 people. Data were collected with a closed questionnaire of 35 items.The results of data analysis showed that the Picture and Picture Learning Model had a positive and significant effect on students’ interest in Learning Christian Religion Education of Grade VII in SMP Negeri 2 DolokSanggul Academic Year 2019/2020 with data analysis as follows: 1. Test requirements for analysis: a) A positive relationship test obtained rxy = 0.745 rtable = 0.349; b) Significant relationship test obtained tcount = 6.109 ttable = 1.697 between variable X with variable Y. 2. Influence test: a) Regression equation test obtained a regression equation with a regression determination coefficient r ^ 2 = 55, 5% and Fcount Ftable = 1.92 1.62, thus Ha and H0 were rejected. There is a positive and significant effect of the Picture and Picture Learning Model on students’ interest in Learning Christian Religion Education of Grade VII in SMP Negeri 2 DolokSanggul Academic Year 2019/2020. Keywords: Picture and picture Learning Model, Students’ Learning Interest, Christian Religion Education
Pengaruh Metode Problem Posing terhadap Berpikir Kritis dalam Pembelajaran Pendidikan Agama Kristen Siswa Kelas X SMA PGRI Siborongborong
Authors: Br. Sianturi Yuri Anty 
Published: May 2021

ABSTRACT The purpose of this study is to experience the positive and significant influence of the use of Problem Posing Methods on Critical Thinking during the Learning PAK Students Class X SMA PGRI Siborongborong 2020/2021 Learning Year. The methods used are quantitative methods. The population of students in class X SMA PGRI Siborongborong approximately 392 people and a sample taken from the 22% the number of 86 people. Data were collected with a positive closed questionnaire into 33 items. The results of the data analysis showed that there was a positive and significant effect of the Positive Problem Method on Critical Thinking in PAK Learning as evidenced by the analytical data: a) positive correlation test found rxy value = 0.364 rtabel (a = 0.05, n = 86) = 0.213. b) Significant relationship test obtained calculation value = 3,583 ttable (a = 0.05, dk = n-2 = 84) = 2,000. c) Regression of the equation. d) Regression determination (r2) = 13.3% thus H0 is rejected and Ha is accepted.Keywords: Problem Posing Method, Critical Thinking
Mencari Kerajaan Allah Dan Kebenarannya Dan Implementasinya Bagi Kehidupan Orang Kristen Masa Kini (Studi Eksegetis Matius 6:33)
Authors: Siketang Sonta 
Published: May 2021

AbstrakPenelitian ini bertujuan untuk mengetahui makna teologis “Kerajaan Allah dan kebenarannya” berdasarkan studi eksegetis Matius 6:33 dan untuk mengetahui implementasinya bagi kehidupan orang Kristen masa kini. Metode penelitian dalam penulisan karya ilmiah ini adalah metode kualitatif, yakni dengan pendekatan studi eksegetis. Di dalam penelitian dan pembahasan terdapat hasil, yaitu: kerajaan Allah adalah kegiatannya yang mengadakan ruang dan kebebasan bagi manusia yang tertindas, kerajaan itu datang dengan keadilan yang menyelamatkan, membebaskan manusia dari kuasa Mamon (harta, milik, nama, dll), membebaskan dari kekuatiran hidup pada saat ini dan pada waktu yang akan datang (makanan, minuman dan pakaian) serta memberikan kepadanya kepercayaan bahwa Allah sebagai Bapa yang menjaga dan memelihara kehidupannya sepenuhnya; mencari kerajaan Allah dan kebenarannya adalah perioritas orang Kristen; dan Allah akan memelihara orang yang mengutamakan Dia.Penelitian ini mengambil kesimpulan bahwa manusia diperintahkan Allah untuk mengutamakan mencari kerajaan Allah dan kebenarannya, karena hanya Allah saja yang berkuasa atas manusia dan hanya Dia saja yang benar, kemudian Yesus mengungkapkan ada janji yang akan diberikan Allah yang bagi orang yang mencari kerajaan Allah dan kebenarannya, yaitu pemeliharaan-Nya. Sebagai orang Kristen yang percaya kepada Yesus Kristus harus mengutamakan mencari kerajaan Allah dan kebenarannya dengan segenap hati, jiwa dan perbuatannya secara terus-menerus.Kata kunci : Kerajaan Allah, Kebenaran dan Pemeliharaan. Abstract This study aims to determine the theological meaning of "the kingdom of God and truth (exegetical study of Matthew 6:33) and to find out its implementation for the lives of Christians present time. The research method in writing scientific papers is a qualitative method, namely the exegetical study approach. In the research and discussion there are results, namely: the kingdom of God is an activity that provides space and freedom for oppressed humans, the kingdom comes with justice that saves, frees humans from the power of Mammon (property, property, name, etc.), frees from worries. live in the present and in the time to come (food, drink and clothing) and give him the confidence that God is the Father who keeps and takes care of his life completely; seeking the kingdom of God and its righteousness is a Christian priority; and Allah will take care of those who put Him first. This research concludes that humans are ordered by God to prioritize seeking God's kingdom and its truth, because only God alone has power over humans and only He is true, then Jesus revealed that there is a promise that God will give for those who seek God's kingdom and its truth. namely His care. As a Christian who believes in Jesus Christ, he must give priority to seeking the kingdom of God and its righteousness with all his heart, soul and deeds continuously.Keywords: Kingdom of God, Truth and Care
Analisis Integritas Dan Profesionalisme Guru Pendidikan Agama Kristen di SMP Se-Kecamatan Pangaribuan Tahun Ajaran 2020/2021
Authors: Sormin Lentina 
Published: May 2021

Abstrak : Tujuan penelitian ini adalah untuk mengetahui besarnya persentase Integritas Dan Profesionalisme Guru Pendidikan Agama Kristen di SMP Se-Kecamatan Pangaribuan Tahun Ajaran 2020/2021, dengan hipotesis Integritas Dan Profesionalisme Guru Pendidikan Agama Kristen di SMP Se-Kecamatan Pangaribuan Tahun Ajaran 2020/2021 ≥ 75% dari yang di harapkan. Populasi berjumlah 204 orang dengan sampel 62 orang. Data dikumpulkan dengan angket tertutup sebanyak 32 item yang disusun sendiri oleh peneliti berdasarkan indikator sesuai teori dan telah diuji validitas dan reliabilitasnya. Analisis data menggunakan rumus t-test 1 sampel, dan diperoleh data bahwa menurut responden Integritas Dan Profesionalisme Guru Pendidikan Agama Kristen di SMP Se-Kecamatan Pangaribuan Tahun Ajaran 2020/2021 ≥ 75% dari yang diharapkan yaitu sebesar 80,96% dengan thitungttabel sebesar 4,389 1,671, dengan demikian Ho ditolak dan Ha diterima.
A Cross Sectional Study to Assess the Levels of Depression and Anxiety in Patients with Chronic Obstruction Pulmonary Disease in a Tertiary Care Hospital
Authors: Sinha Richa , Gupta Trisha , Maheshwari Sonam 
Published: May 2021

Objective: In the present study, demographic profile, knowledge and motivation of COPD patients attending tertiary hospital, the level of anxiety and depression is assessed. Materials and Methods: This cross-sectional study was carried out on consecutive patients with COPD during their routine out- and in-patient visits in the tertiary care hospital during 4 months (April 2019 to July 2019). Physician confirmed cases of more than 1-year duration were included in the study. Thus 194 COPD patients were admitted in the ward. They were interviewed by using HADS scale and Modified Morisky scale. The diagnosis of COPD was confirmed by Chest X- ray and Spirometery test and a history of exacerbation or hospitalization over past 6 months was also obtained. The chi square-test, t-test and one-way analysis of variance were used in the univariate analyses, whilst regression was used in the multiple variable analyses.Results: A total of 194 COPD individuals, 124 Males and 70 Females were enrolled in the study. The mean age of the respondents was 49.16 ± 8.20 (25-62) years. The mean scores for anxiety and depression were 19.12± 2.38 and 11.54± 2.50 respectively. Both anxiety and depression scores were statistically significant between the gender. Among males 70 % cases were having no comorbid conditions; however, 57.10 % females were having more than two comorbid conditions. Conclusion: Present study illustrates that anxiety and depression are common in patients with COPD, furthermore, patients with depressive disorders have more comorbidities in comparison with patient with anxiety.
Abordagens de conceitos introdutórios de função por meio da resolução de problemas: uma experiência no estágio supervisionado
Authors: Ribeiro Dulcyene Maria , Corassa Thalia Falquievicz , Gonçalves Bruno 
Published: May 2021

O presente artigo apresenta considerações e reflexões acerca de algumas atividades realizadas com uma turma do 1° ano do Ensino Médio, com as quais trabalhamos com o conteúdo de introdução às funções, utilizando como metodologia de ensino-aprendizagem a resolução de problemas, conforme preconizada por Onuchic e Allevato (2011), Polya (1997) e Butts (1997), entre outros. Tais atividades foram desenvolvidas durante o estágio supervisionado, no primeiro semestre do ano de 2019, na disciplina de Metodologia e Prática de Ensino de Matemática – Estágio Supervisionado II, ofertada no quarto ano do Curso Licenciatura em Matemática da Universidade Estadual do Oeste do Paraná, campus de Cascavel. Além de relatar as atividades desenvolvidas e o trabalho realizado pelos alunos, apresentamos uma breve fundamentação sobre a resolução de problemas. Por fim concluímos que a prática realizada proporcionou aos professores em formação um rico processo de experimentar e refletir sobre a realização de atividades por meio da resolução de problemas e aos alunos do Ensino Médio a possibilidade de se envolverem e participarem de uma atividade em que puderam se expor, utilizar seus conhecimentos anteriores e aprenderem com os erros. What do you want to do ?New mailCopy
The Fundamentals of Typography
Authors: Ambrose Gavin , Harris Paul , Theodosiou Sallyanne 
Published: May 2021

Demonstrating the power and variety of typography from hand-drawn to kinetic, this fully updated new edition of The Fundamentals of Typography covers the principles of using type across a range of media.
Starting with a comprehensive introduction to the history of typography, the authors provide detailed explanations and inspirational examples of type usage from leading practitioners from around the world. With expanded practice exercises and four new case studies, this book gives students everything they need to know to use type effectively and creatively.
«Playback theatre» як форма «entertainment» у сучасній культурі
Authors: CHUMACHENKO Olena 
Published: May 2021

Розглянуто «рlayback theatre» як форму «еntertainment» у сучасній культурі. Окреслено, що «рlayback theatre», виступаючи різновидом інтерактивного театру імпровізації, включає в себе дві основні комплементарні практики, де є партиципативні й емерсивні аспекти. Охарактеризовано такі структурні елементи «рlayback theatre» як: «рідка скульптура» (заснована Дж. Фоксом); «трансформація», «хор», «п’ять елементів», «картина», «фото», «колаж», «Доміно», «Розетка», «Епізоди». «Playback theatre» як форма «еntertainment» у сучасній культурі виступає альтернативою «технообразам», підтримуючи традиційні «текстообрази» з властивою їм інтерпретаційною особливістю. Сутність «рlayback theatre» у сучасному контексті полягає у активізації «нового мистецтва» для виявлення розкриття внутрішнього потенціалу особистості.