bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of fluoxetine and imipramine on the improvement of depressive-like behaviors and HPA axis (hypothalamic-pituitary-adrenal cortex) activity – an animal model
Authors: Khaleel Raghad Abdulsalam , Shareef Saja Majeed , Hameed Zinah Essam , Alsaraf Khulood Majid , Nassar Maadh Fawzi 
Published: November 2021

Depression is one of the most common mental disorders and numerous medications are used to reduce the psychotic symptoms.
The aim of this study was to evaluate the therapeutic effects of two commonly used antidepressant drugs, including Fluoxetine (Flx) and Imipramine (IMP) to improve depressive-like behaviors as well as the activity of hypothalamic pituitary-adrenal cortex (HPA).
Methods: Initially, 40 adult male albino rats weighing 25±5g were selected for this experimental study. The animals were kept or housed in separate cages under standard temperature (25±1°C) and light-dark conditions (12 hours light/dark cycle). Rats were divided into four groups: each group containing 10 rats, control, immobility stress, Flx receiver, and IMP receiver. Polyethylene restrainer was used to induce immobility stress for 14 days. Finally, the parameters of IMT, ST, serum levels of corticosterone and glucose were evaluated in all four mentioned groups.
Results: The results showed that the patient group's immobility time (IMT) increased compared to the control group, but the patient group's swimming time (ST) decreased compared to the control group. The effect of immobility stress on IMT, ST, corticosterone, and glucose factors in the patient group was increasing and decreasing, respectively, whereas the effect of Flx drug on these mentioned factors was decreasing, increasing and respectively, while the effect of IMP on all mentioned factors was decreasing and increasing, respectively.
Conclusion: Based on the results, it can be concluded that the antidepressant Flx and IMP drugs have various effects on the HPA activity, and the application of immobility stress causes depressive-behavior. Moreover, Flx is more effective than IMP in the treatment of depressive behaviors
Development of a method for maintaining the performance of drilling fluids during transportation by Platform Supply Vessel
Authors: Maryanov Denis 
Published: November 2021

The object of research is the process of transportation of drilling fluid used for lubrication and cooling of drilling equipment of offshore oil production platforms. The subject of the study is the stratification of the density of the drilling fluid along the height of the cargo tank in which it is transported. The technology of transportation of drilling fluid on the Platform Supply Vessel is considered. A problematic point in ensuring this process is that during the transportation of drilling fluids, due to the action of gravitational forces on organic and inorganic compounds in their volume, there is a latent change in their dispersion over the volume of the fluid. This leads to the stratification and stratification of the fluid density along the height, as well as to the formation of sediments at the bottom of the cargo tanks, in which the drilling fluid is transported. The study is aimed at developing a technology that maintains a constant value of the density of the drilling fluid along the depth of the tank in which it is transported. The studies were carried out in the vessel system for transporting drilling fluid of a specialized marine vessel of the Platform Supply Vessel type with a deadweight of 5850 tons. It is experimentally established that for a transportation time of 6–36 hours, the density stratification of the drilling fluid is 3.04–32.04 %. As a method that ensures the minimum stratification of the density of the drilling fluid during its transportation, it is proposed to use an additional X-shaped circulation of the drilling fluid in the volume of adjacent cargo tanks. Studies have confirmed that the density stratification over a time period of 6–36 hours decreases to a range of 2.30–9.01 %. The complex use of additional X-shaped circulation and simultaneous air supply to the bottom of the cargo tank provides a density stratification value of 0.73–2.93 %. The proposed technology was tested on a specialized seagoing vessel of the Platform Supply Vessel type with a deadweight of 5850 tons and can be used on offshore vessels that ensure the operation of offshore oil production platforms.
Development of the system of energy and resource saving during the operation of the gas pumping unit
Authors: Kologrivov Mykhailo , Buzovskyi Vitalii 
Published: November 2021

The object of research is the fuel gas system of a gas turbine engine. The study of the use of secondary energy resources of the gas-pumping unit at the compressor station of the main pipeline has been carried out. The work of a gas turbine engine, including the work of the fuel gas system, is considered. The main drawback of the fuel gas system is revealed – ineffective use of excess gas pressure. An informational analysis of the options that eliminate the identified drawback is carried out. It is shown that in order to eliminate the disadvantage, it is advisable to use a turbo-expander at the compressor station to utilize the excess pressure of the fuel gas. It is also shown that the operation of a fuel gas turboexpander to drive an additional air compressor as part of a gas turbine engine is impractical. An expander-generator set with the generation of additional electricity at the compressor station is recommended for use.
Modeling the operation of the utilization system made it possible to recommend constructive proposals for its improvement. A schematic diagram of a system for the complex utilization of excess pressure of fuel gas and heat of combustion products from the operation of a gas turbine engine is proposed. The system of complex utilization includes parts-generator unit, heat exchanger for cooling process gas and heat exchanger for firing gas. Regenerative heating of fuel gas up to 250 °С reduces energy consumption for heating it up to the ignition temperature.
A model of a robot installation of the type GPU 16/56-1.44 (Ukraine) is carried out. It is determined that when a component engine of the J-59 (Ukraine) type with a shaft power of 16 MW operates, it is possible to additionally receive 102 kW of electricity and save 64 m3/h of fuel gas. It is revealed that the subcooling of the process gas does not play a significant role in reducing energy consumption during its transportation. It is recommended to use the process gas to heat the cold fuel gas stream downstream of the turboexpander to positive temperatures. The integrated utilization system is not a simple connection of an expander-generator set and two heat exchangers along the flow of the fuel gas. As a result of its operation, a significant reduction in the consumption of fuel gas and electricity is achieved. The disadvantages that hinder the implementation of a comprehensive disposal system are identified. This is the use of equipment for generating electricity at a compressor station. It is uncharacteristic for the operation of the station and requires additional qualifications in service. It is also required that the characteristics of industrial expander-generator sets correspond to the fuel gas consumption of a gas turbine engine.
Development of information supplement of reporting forms as an effective way of business management
Authors: Hevchuk Anna , Shevchuk Liudmyla 
Published: November 2021

The object of research is the information support of settlement operations as an effective way of business management to minimize risks and their consequences in the agricultural sector in today's global economy. This study is due to the lack of accounting practices, namely the low informativeness of reporting forms for business management, which needs to be improved in terms of settlement operations, which should be aimed at the efficient use of resources by agricultural companies.
The analysis of the current state of reporting as information support of business management calculations is carried out. It is determined that the internal and financial reporting does not contain sufficient information on the settlement operations of business units, especially taking into account the emergence of new settlement instruments and a system of support for their implementation, including agricultural receipts. The use of agricultural receipts as a new financial calculation tool and an alternative mechanism for agribusiness lending requires informational reporting, which allows to increase the efficiency of management decisions. The study used the stages of modeling the calculation management process for users. For their implementation, the main directions for supplementing the content and components of financial statements f. No. 1 «Balance Sheet» (Statement of Financial Position) and f. No. 5 «Notes to the annual financial statements» are suggested. Management reporting is proposed, namely «Report on the status of settlements within accounts payable» and «Report on the status of settlements within accounts receivable». As well as the development of Section 4 «Risk Report» and Section 5 «Liquidity and Liabilities» of the Management Report. This provides an opportunity to generate useful, objective and relevant information adapted to the taxonomy of financial reporting (according to international financial reporting standards) in Ukraine. This information will assist company management, current and potential investors, lenders and other lenders in making effective management decisions. Compared to similar known methods, the proposed approaches allow to effectively manage the business, providing a high level of control over the state of settlements. The received information support will allow to minimize losses through the impact on risks due to the predictability of their potential consequences, which will contribute to the observance of financial independence and development of the agricultural sector.
Development of a method for producing a healthy drink based on fermented beet juice
Authors: Stetsenko Natalia , Goyko Iryna 
Published: November 2021

The object of research is a method of producing a fermented drink from natural raw materials, the consumption of which will provide the human body with probiotics, prebiotics, vitamins and antioxidants. The work used general scientific research methods, in particular, analysis and synthesis, as well as physicochemical methods for determining the composition and properties of raw materials and the finished product. Beetroot and its juice are insufficiently used in the food and processing industries, therefore this particular type of raw material has great reserves and prospects for creating health products. The work is aimed at improving the method of obtaining fermented beet juice enriched with ginger extract. For the production of the drink, the root crops of the Cylindra variety were chosen, which had a high content of dry substances and sugars, and were also characterized by a better storage capacity with minimal losses of biologically active substances. It has been established that when obtaining juice, it is advisable to process crushed pectolytic beets with the enzyme preparation Fructocyme MA-X-Press (manufacturer Russia). This makes it possible to increase the juice yield by 14.9 %, the amount of dry matter by 2.1 % and the sugar content by 1.7 %. To ferment the juice used bacterial preparations of lacto- and bifidobacteria in the amount of 5 % by weight of raw materials. The fermentation was carried out at a temperature of 37 °C for 24 hours. It was found that when using the preparation of B. longum bifidobacteria, which have good stability in an acidic medium, a higher fermentation rate is achieved. To enrich the drink with substances with antioxidant properties, ginger root extract was used. The health-improving effect of the fermented drink is due to the use of exclusively natural plant materials and the use of probiotic cultures of microorganisms in the technological process, which improve the functioning of the gastrointestinal tract and are factors that stimulate the immune system.
An audit of HIV-infected Patients Admitted to Helen Joseph Hospital in Johannesburg, South Africa
Authors: Yudelowitz Gregory , Ive Prudence , Fox Mathew 
Published: November 2021

ABSTRACT

Background: South Africa has the largest HIV-infected population and treatment programme in the world. ART access has increased since 2004 with the current policy of universal test and treat (UTT). South Africa has had some success toward the UNAIDS 90-90-90 targets but high numbers of HIV related complications and treatment failure persist despite universal access to ART. The aim of this study was to assess the proportion of patients admitted to a general medical ward with HIV infection and to calculate the median CD4 count of these patients.

Methods: A clinical audit in which baseline data was collected from all patients admitted to a single medical unit at Helen Joseph Hospital in Johannesburg from September 2018 to January 2019. The number of admissions of people living with HIV (PLWH) was assessed and median CD4 count and viral loads were calculated. The indications for admission of PLWH and HIV-negative patients were also compared.

Results: The median CD4 cell count of PLWH was 67 cells/µl (IQR 23-259.5). Of the 794 medical admissions 42.4% were HIV-infected. Of the cohort of HIV-infected patients, over a quarter were newly diagnosed on admission. Furthermore, 46.1% of patients on treatment were failing ART. More than 10% of HIV-infected patients had interrupted treatment and 10.5% of patients previously known to be HIV-infected had not yet initiated treatment. AIDS-defining conditions accounted for 40.1% of the admissions.

Conclusion: Despite a policy of UTT, a high proportion of medical admissions to a public hospital in South Africa are in PLWH. Median CD4 counts remain low in hospitalised HIV positive patients despite universal access to ART. Large numbers of PLWH are not accessing or are disengaging from HIV care.
Evaluation of Growth Performance, Carcass Characteristics and Meat Quality of Shaziling Pigs and its Hybrids Crossbred with Berkshire Pigs
Authors: Chen C. , Deng Y. , Ren H.B. , Zhu J. , Cui Q.M. , Hu X.G. , Peng Y.L. 
Published: November 2021

Background: The Chinese Shaziling pig is representative of good meat quality but has been scarcely utilized on commercial farms because of the unpleasing growth and carcass traits. Methods: The growth performance, carcass characteristics, meat quality and fatty acids profile were analyzed among (Berkshire × Shaziling) × (Berkshire × Shaziling) (BS × BS), BS × S, Shaziling (S × S) and S × BS pigs. Result: BS × BS pigs exhibited higher growth rate and superior carcass performance. Each breed possessed desirable meat quality, as evidenced by moderate pH, color score, IMF content and shear force value, among which the performance of S × BS pigs was prominent. Take account of the contents of SFAs, MUFAs, PUFAs and PUFAs/SFAs value, the eating quality of S × BS pigs was favorable and the meat of BS × BS pigs, by contrast, was helpful for human health with advanced nutritional value. In summary, BS × BS pigs is more effective for commercial development of Shaziling pigs and providing healthy pork products.
Evaluation of teachers' views on the use of learning technologies in mathematics lessons in preschool and primary schools
Authors: Fariza Kinzhibayeva , Assel Akpayeva , Gulzhan Yergalieva , Marzhangul Mynzhassarova 
Published: November 2021

The purpose of this research is to evaluate the problems encountered in the process of realizing the continuity of preschool and primary school mathematics education and to determine the use of technology in mathematics education in line with the opinions of teachers. The research is a phenomenological study within the scope of qualitative research method. The research was conducted with 40 classroom teachers working in various primary schools in the province of Almaty, Kazakhstan, in the 2020-2021 academic year. The research data were collected with a semi-structured interview form prepared by the researcher and consisting of five open-ended questions, and analyzed with the descriptive method. As a result of the research, students were found to be prejudiced against the course, and the inadequacy of course materials, learning methods and techniques, and course activities were shown as the reasons that negatively affect education. In addition, it has been determined that the rate of teachers to prefer classical methods in education is much higher than new learning methods and techniques and use of technology.
Keywords: Mathematics; mathematics education; preschool mathematics education; primary school mathematics education; teachers’ opinion.
Social network activity of students in conditions of an epidemiological threat
Authors: Kalinina Natalia V. , Tkhugo Muliat M. , Shipovskaya Lyudmila P. , Matafonova Svetlana I. , Khudyakova Tatyana L. , Kazakova Lyubov I. 
Published: November 2021

The period of restrictions on social contacts introduced by the governments of different countries increased the time spent by users in social networks. The paper aims to analyze the Internet activity of students in social networks as a way of overcoming interaction difficulties in the context of an epidemiological threat. The research used the observation method and questionnaires to collect data for this research. The sample for the research consisted of 300 students between ages of 18 and 22, who were purposively sampled. Using content analysis and the statistical program for social sciences, the collected data were analyzed. As a result of the study, it was established that the Internet activity of students in social networks in the context of an epidemiological threat and globalization in general, determines the level of development and the content framework of a person's self-attitude.

Keywords: activity; epidemiological threat; social network; manifestations of activity; self-attitude
Algorithmic methodological and mathematical literacy of the future primary education teacher: Perspective of learning technology
Authors: Astambayeva Zhupat , Zhumabayeva Aziya , Romanova Marina , Nygymanova Nurbanu , Bazarbekova Rabiga , Nizamova Makhinur 
Published: November 2021

The relevance of the study is based on the development of algorithmic methodological and mathematical literacy of future primary school teachers, the use of knowledge, practical skills and abilities acquired at universities in real professional activities, in everyday life. In this regard, this article is aimed at determining the dynamics of the development of algorithmic methodological and mathematical literacy of the future teacher through exercises of various content and directions. The main bases of research on the development of algorithmic, methodological and mathematical literacy of the future teacher of primary education were taken as systematic, operational, anthropological, axiological and competence. Systematic platform for the development of literacy on the basis of a systematic position in teaching methodological and mathematical materials were considered. The research included algorithmic literacy of 68 new students, a survey of 3rd year students 38 3rd year students and 38 primary school teachers. The essence and methods of teaching exercises aimed at developing literacy were revealed. The materials of the article are practical assistance to young teachers of pedagogical higher educational institutions of specialties 6B013 – Pedagogy and methods of primary education, pedagogical colleges and schools.
Keywords: algorithmic methodological and mathematical literacy; functional literacy; algorithmic literacy; mathematical literacy; methodological literacy; exercises aimed at developing literacy.
Dashboard proposal implemented according to an analysis developed on the KNIME platform
Authors: Maraza-Quispe Benjamin , Quispe-Figueroa Ricardo Carlos , Valderrama-Solis Manuel Alejandro , Maraza-Quispe Benjamin 
Published: November 2021

The objective of the research is to develop a methodology to analyse a set of data extracted from a learning management system, in order to implement a dashboard, which can be used by teachers to make timely and relevant decisions to improve the teaching–learning processes. The methodology used consisted of analysing 9,257 records extracted through simple random sampling from a population of 100,000 records. The indicators analysed were number of accesses, course grades, time spent, number of courses enrolled and number of activities developed. The results show that the data analysis was carried out on the (o Konstanz Information Miner (KNIME) data mining analysis platform, and the model was implemented in five phases: requirements definition, model design, development, implementation and evaluation of results. The results are taken as a recommendation to design and implement a customised dashboard for teachers to identify observable behavioural patterns that allow them to make decisions to improve the teaching–learning processes of students.
Keywords: Analytics, dashboard, KNIME Learning, personalised, teaching
Formation of information and professional competence of primary school teachers with Online Education.
Authors: Uaidullakyzy Elmira 
Published: November 2021

The aim of this research is to provide the formation of knowledge and professional competence of primary school teachers with online education. The research was conducted in the summer term of 2020-2021. 436 primary school teachers who continue their studies in Kazakhstan participated in the research. For the research, 6 weeks of online training on professional competence was given to primary school teachers. The measurement tool called "Online Education and Vocational Competence", which was developed by the researchers and compiled by taking the opinion of experts in the field, was applied to primary school teachers. The data was shared with primary school teachers from the internet with an online questionnaire, and their participation was ensured and collected. The collected data were analyzed using the SPSS program. Frequency, percentage, average, standard deviation, minimum and maximum values ​​were used to analyze the data obtained from the Vocational Competence measurement tool.According to the results of the research, the information was examined and in the light of the obtained information, it was observed that the distance education and professional competence status of the primary school teachers showed positive results. Even though their opinions are high, it has been concluded that the online usage status of male teachers is higher than female teachers.
Keywords: Primary School Teacher, Zoom Application, Online Education, Professional Seniority, Distance Education
Information and communication technology and critical thinking in university students
Authors: Kremenkova Lucie , Plevová Irena , Pugnerova Michaela , Sedlakova Eva 
Published: November 2021

The 21st century is referred to as the digital age, which places demands not only on the ability to work with information but also on being able to understand them as well as evaluate its relevance. The aim of this paper was to find out how ICT competences affect the individual domains of critical thinking in university students. The sample consisted of 624 university students. The data were collected using the Critical Thinking Disposition Inventory (CTDI) and the Information and Communication Technology Competence (ICTC). The results of the correlation analyses revealed weak to medium relationships among all of the observed domains. The subsequent linear regression models showed that all of the domains of critical thinking were affected by ICT competences. In this context, the most interesting was the effect of ICT competences on open mindedness while the effect on the remaining factors of critical thinking was weaker.

Keywords: critical thinking; CTDI; ICTC; information and communication technology; university students