bluuebunny/crossref_metadata_2025_split huggingface dataset:
Leveraging Clinical Informatics Tools to Extract Cumulative Anthracycline Exposure, Measure Cardiovascular Outcomes, and Assess Guideline Adherence for Children With Cancer
Authors: Noyd David H. , Berkman Amy , Howell Claire , Power Steve , Kreissman Susan G. , Landstrom Andrew P. , Khouri Michel , Oeffinger Kevin C. , Kibbe Warren A. 
Published: October 2021

PURPOSE Cardiovascular disease is a significant cause of late morbidity and mortality in survivors of childhood cancer. Clinical informatics tools could enhance provider adherence to echocardiogram guidelines for early detection of late-onset cardiomyopathy. METHODS Cancer registry data were linked to electronic health record data. Structured query language facilitated the construction of anthracycline-exposed cohorts at a single institution. Primary outcomes included the data quality from automatic anthracycline extraction, sensitivity of International Classification of Disease coding for heart failure, and adherence to echocardiogram guideline recommendations. RESULTS The final analytic cohort included 385 pediatric oncology patients diagnosed between July 1, 2013, and December 31, 2018, among whom 194 were classified as no anthracycline exposure, 143 had low anthracycline exposure (< 250 mg/m2), and 48 had high anthracycline exposure (≥ 250 mg/m2). Manual review of anthracycline exposure was highly concordant (95%) with the automatic extraction. Among the unexposed group, 15% had an anthracycline administered at an outside institution not captured by standard query language coding. Manual review of echocardiogram parameters and clinic notes yielded a sensitivity of 75%, specificity of 98%, and positive predictive value of 68% for International Classification of Disease coding of heart failure. For patients with anthracycline exposure, 78.5% (n = 62) were adherent to guideline recommendations for echocardiogram surveillance. There were significant association with provider adherence and race and ethnicity ( P = .047), and 50% of patients with Spanish as their primary language were adherent compared with 90% of patients with English as their primary language ( P = .003). CONCLUSION Extraction of treatment exposures from the electronic health record through clinical informatics and integration with cancer registry data represents a feasible approach to assess cardiovascular disease outcomes and adherence to guideline recommendations for survivors.
Ladies Aid as Labor History
Authors: Fahrenthold Stacy D. 
Published: October 2021

AbstractIn the Arabic-speaking mahjar (diaspora), the plight of the working poor was the focus of women’s philanthropy. Scholarship on welfare relief in the interwar Syrian, Lebanese, and Palestinian diaspora currently situates it within a gendered politics of benevolence. This article reconsiders that frame and argues for a class-centered reassessment of “ladies aid” politics exploring the intersections of women’s relief with proletarian mutual aid strategies. Founded in 1917, the Syrian Ladies Aid Society (SLAS) of Boston provided food, shelter, education, and employment to Syrian workers. SLAS volunteers understood their efforts as mitigating the precarities imposed on Syrian workers by the global capitalist labor system. Theirs was both a women’s organization and a proletarian movement led by Syrian women. Drawing from SLAS records and the Syrian American press, the article centers Syrian American women within processes of working-class formation and concludes that labor history of the interwar mahjar requires focus on spaces of social reproduction beyond the factory floor.
Effects of Prolonged Sitting with or without Elastic Garments on Limb Volume, Arterial Blood Flow, and Muscle Oxygenation
Authors: KUROSAWA YUKO , NIRENGI SHINSUKE , TABATA IZUMI , ISAKA TADAO , CLARK JOSEPH F. , HAMAOKA TAKAFUMI 
Published: October 2021

ABSTRACT

Purpose
The physiological response induced by acute prolonged sitting is not fully understood. Therefore, we examined the effects of 8-h constant sitting on microcirculation and associated factors in the lower extremity among healthy males. We also evaluated the protective effects of lower-pressure thigh-length elastic compression garments on these parameters.

Methods
Nine healthy males (age, 22.6 ± 1.4 yr; body mass index, 22.4 ± 1.8 kg·m−2) completed the 8-h constant sitting experiment. Following baseline measurements, each subject was randomized to wear a lower-pressure elastic garment on the right or left leg from the inguinal region to the ankle joint, with the noncompressed contralateral leg as a control. Circumferences of the calf and malleolus, extracellular water contents, blood flow and shear rate of the dorsal metatarsal artery, and oxygen dynamics in the gastrocnemius muscles were measured in both extremities before and during 8-h constant sitting.

Results
Compared with baseline values, 8-h constant sitting caused enlargement of circumferences (calf, 2.4% ± 0.7%; malleolus, 2.7% ± 1.4%), retention of extracellular water in lower extremity muscles (10.1% ± 1.78%), deterioration of the blood flow (61.4% ± 16.2% of baseline) and shear rate of the dorsal metatarsal artery, and decrease in oxygenated hemoglobin and total hemoglobin levels in the gastrocnemius muscle (P < 0.05, respectively). When subjects wore the lower-pressure thigh-length compression garment, a significant reduction of these effects was observed (P < 0.05, for all).

Conclusions
Prolonged sitting for 8 h induced edema, as well as deterioration of the arterial blood flow, shear rate, and microcirculation in lower limb muscles. Conversely, application of the lower-pressure elastic garment successfully prevented the pathophysiological deterioration associated with prolonged sitting.
Cultural adaptation, validity and reliability of the Turkish version of the Örebro Musculoskeletal Pain Questionnaire in acute and subacute neck pain
Authors: Şimşek Şule , Yağcı Nesrin , Şenol Hande 
Published: October 2021

Background/aims The Örebro Musculoskeletal Pain Questionnaire is categorised as a ‘yellow flag’ pain-associated psychological distress screening tool, which predicts long-term disability. The aim of this study was to assess the validity and reliability of the Turkish translation of the Örebro Musculoskeletal Pain Questionnaire in patients with acute and subacute neck pain. Methods The test–retest reliability and internal consistency were assessed with the intraclass correlation coefficient and Cronbach's α. Construct validity was assessed with a visual analogue scale, the Neck Disability Index and the Fear Avoidance Belief Questionnaire. Results Cronbach's α value was found to be 0.790, test–retest reliability was 0.99. The intraclass correlation coefficient was 0.999 (95% confidence interval: 0.998–0.999; P=0.000). The Örebro Musculoskeletal Pain Questionnaire showed a moderate positive correlation with the Neck Disability Index (r=0.544; P=0.0001), a weak correlation with the Fear Avoidance Belief Questionnaire (r=0.264; P=0.0001) but no correlation with the visual analogue scale. Conclusions The Turkish version of the Örebro Musculoskeletal Pain Questionnaire is a valid, reliable and acceptable screening tool in patients with acute and subacute neck pain.
What About Wood?—“Nonwood” Construction Experts' Perceptions of Environmental Regulation, Business Environment, and Future Trends in Residential Multistory Building in Finland
Authors: Aaltonen Aleksi , Hurmekoski Elias , Korhonen Jaana 
Published: October 2021

Abstract
Despite the sustained interest in multistory wood-frame construction (WMC) along with an expanding bioeconomy, the rate of market uptake has been modest outside North America. Changing environmental values and regulation are expected to boost WMC adoption along with an expanding bioeconomy, yet the future prospects of WMC are typically explored with an empirical focus on the actors that are already active in WMC. To address the possible bias, this paper elicits the views of nonwood actors (i.e., construction company managers and executives in the areas of procurement and project planning with no prior experience in WMC), through 10 semistructured interviews. The results indicate that the nonwood actors do not necessarily oppose WMC as such, but there remain competitive barriers for a major market growth of WMC related to, for example, lack of standardization and significant enough productivity benefits to motivate adopting a new potentially risky construction practice. Based on comparisons with previous literature, the most notable differences in opinions between wood actors and nonwood actors regarded the direction and strength of the impact of consumer preferences on WMC demand. While acknowledging that this is a crude comparison without statistical significance, one can observe similarities in the distribution of answers for the questions unrelated to WMC, but more dispersion for those addressing WMC. Yet, while the attitudes toward wood as a construction material seem to differ, both the wood and nonwood actors seem to regard the doubling of the market share of WMC in Finland by 2030 as feasible.
Sex-based differences in the manifestations and complications of sickle cell disease: Report from the Sickle Cell Disease Implementation Consortium
Authors: Masese Rita V. , Bulgin Dominique , Knisely Mitchell R. , Preiss Liliana , Stevenson Eleanor , Hankins Jane S. , Treadwell Marsha J. , King Allison A. , Gordeuk Victor R. , Kanter Julie , Gibson Robert , Glassberg Jeffrey A. , Tanabe Paula , Shah Nirmish ,   on behalf of the Sickle Cell Disease Implementation Consortium
Published: October 2021

IntroductionSex-based clinical outcome differences in sickle cell disease (SCD) remain largely unknown despite evidence that female sex is associated with an increased lifespan. To better characterize sex-based differences in SCD, we assessed pain, treatment characteristics, laboratory measures and complications among males and females currently enrolled in the Sickle Cell Disease Implementation Consortium (SCDIC) registry.MethodsThe SCDIC consists of eight comprehensive SCD centers and one data coordinating center that received funding from the National Heart Lung and Blood Institute to improve outcomes for individuals with SCD. Eligibility criteria included: 15 to 45 years of age and a confirmed diagnosis of SCD. Self-report surveys were completed and data were also abstracted from the participants’ medical records.ResultsA total of 2,124 participants were included (mean age: 27.8 years; 56% female). The majority had hemoglobin SS SCD genotype. Females had worse reports of pain severity (mean (SD) T-score 51.6 (9.6) vs 49.3 (10), p<0.001), more vaso-occlusive episodes (p = 0.01) and a higher occurrence of 3 or more hospital admissions in the past year (30.9% vs. 25.5, p = 0.03). On multivariable analysis, males had higher odds of acute chest syndrome (odds ratio (OR) 1.4, p = 0.002), cardiovascular (OR 1.70, p<0.001) and musculoskeletal (OR 1.33, p = 0.0034) complications and lower odds of depression (OR 0.77, p = 0.0381). Females had higher fetal hemoglobin levels with and without hydroxyurea use (9.6% vs 8.5%, p = 0.03 and 3% vs 2.2%, p = 0.0005, respectively).ConclusionOur data suggests that sex differences in clinical outcomes do occur among individuals with SCD. Future research needs to explore the mechanisms underlying these differences.
Exploring the nasopharyngeal microbiota composition in infants with whooping cough: A test-negative case-control study
Authors: Rocafort Muntsa , Henares Desiree , Brotons Pedro , Barrabeig Irene , Launes Cristian , Merdrignac Lore , Valenciano Marta , Domínguez Angela , Godoy Pere , Muñoz-Almagro Carmen 
Published: October 2021

Purpose
The purpose of this study was to characterize the nasopharyngeal microbiota of infants with possible and confirmed pertussis compared to healthy controls.

Methods
This prospective study included all infants <1 year with microbiologically confirmed diagnosis of pertussis attended at a University Hospital over a 12-month period. For each confirmed case, up to 2 consecutive patients within the same age range and meeting the clinical case definition of pertussis but testing PCR-negative were included as possible cases. A third group of asymptomatic infants (healthy controls) were also included. Nasopharyngeal microbiota was characterized by sequencing the V3-V4 region of the 16S rRNA gene. Common respiratory DNA/RNA viral co-infection was tested by multiplex PCR.

Results
Twelve confirmed cases, 21 possible cases and 9 healthy controls were included. Confirmed whooping cough was primarily driven by detection of Bordetella with no other major changes on nasopharyngeal microbiota. Possible cases had limited abundance or absence of Bordetella and a distinctive microbiota with lower bacterial richness and diversity and higher rates of viral co-infection than both confirmed cases and healthy controls. Bordetella reads determined by 16S rRNA gene sequencing were found in all 12 confirmed cases (100%), 3 out of the 21 possible cases (14.3%) but in any healthy control.

Conclusion
This study supports the usefulness of 16S rRNA gene sequencing for improved sensitivity on pertussis diagnosis compared to real-time PCR and to understand other microbial changes occurring in the nasopharynx in children <1 year old with suspected whooping cough compared to healthy controls.
Determinants of birthplace among middle-to lower-class women in Indonesia: A study using the Indonesian Demographic and Health Survey
Authors: Pranata Angga Kresna , Wahyudi Andri Setiya , Handoyo Lukman , Efendi Ferry 
Published: October 2021

Background
One of the factors contributing to a high maternal mortality rate is the utilization of non-healthcare facilities as a birthplace for women. This study analyzed determinants affecting birthplace in middle-to lower-class women in Indonesia.

Methods
This study analyzed the 2017 Indonesian Demographic and Health Survey (IDHS) data. The total national sample size was 49,627 eligible women. Our sample included 11,104 women, aged 15–49, who had delivered babies and were of low-to-middle economic status. The type of survey dataset was individual record dataset. Data were analyzed with chi-square and multivariate logistic regression tests using Stata 16 software.

Results
About 64.99% middle to lower class women in Indonesia delivered in healthcare facilities. Women aged 45–49 (OR = 2.103; 95% CI = 1.13–3.93), who graduated from higher schools (OR = 2.885; 95% CI = 1.76–4.73), whose husbands had higher education (OR = 2.826; 95% CI = 1.69–4.74) and were employed (OR = 2.523; 95% CI = 1.23–5.17), who considered access to healthcare facilities was not a problem (OR = 1.528; 95% CI = 1.28–1.82), who had a single child (OR = 2.349; 95% CI = 1.97–2.80), and who lived in urban areas (OR = 2.930; 95% CI = 2.40–3.57) were determinants that significantly correlated with women giving birth in healthcare facilities.

Conclusion
This study provides insights for policymakers and healthcare centers in the community to strengthen access to healthcare services and devise health promotion strategies for pregnant mothers. Policy interventions designed for middle- to lower-class women should be implemented to support vulnerable groups.
Mobile interventions targeting common mental disorders among pregnant and postpartum women: An equity-focused systematic review
Authors: Saad Ammar , Magwood Olivia , Aubry Tim , Alkhateeb Qasem , Hashmi Syeda Shanza , Hakim Julie , Ford Leanne , Kassam Azaad , Tugwell Peter , Pottie Kevin 
Published: October 2021

IntroductionPregnant and postpartum women face major psychological stressors that put them at higher risk of developing common mental disorders, such as depression and anxiety. Yet, their limited access to and uptake of traditional mental health care is inequitable, especially during the COVID-19 pandemic. Mobile interventions emerged as a potential solution to this discontinued healthcare access, but more knowledge is needed about their effectiveness and impact on health equity. This equity-focused systematic review examined the effectiveness and equity impact of mobile interventions targeting common mental disorders among pregnant and postpartum women.Methods and resultsWe systematically searched MEDLINE, EMBASE, PsychINFO and 3 other databases, from date of database inception and until January 2021, for experimental studies on mobile interventions targeting pregnant and postpartum women. We used pooled and narrative synthesis methods to analyze effectiveness and equity data, critically appraised the methodological rigour of included studies using Cochrane tools, and assessed the certainty of evidence using the GRADE approach. Our search identified 6148 records, of which 18 randomized and non-randomized controlled trials were included. Mobile interventions had a clinically important impact on reducing the occurrence of depression (OR = 0.51 [95% CI 0.41 to 0.64]; absolute risk reduction RD: 7.14% [95% CI 4.92 to 9.36]; p<0.001) and preventing its severity perinatally (MD = -3.07; 95% CI -4.68 to -1.46; p<0.001). Mobile cognitive behavioural therapy (CBT) was effective in managing postpartum depression (MD = -6.87; 95% CI -7.92 to -5.82; p<0.001), whereas other support-based interventions had no added benefit. Results on anxiety outcomes and utilization of care were limited. Our equity-focused analyses showed that ethnicity, age, education, and being primiparous were characteristics of influence to the effectiveness of mobile interventions.ConclusionAs the COVID-19 pandemic has increased the need for virtual mental health care, mobile interventions show promise in preventing and managing common mental disorders among pregnant and postpartum women. Such interventions carry the potential to address health inequity but more rigorous research that examines patients’ intersecting social identities is needed.
Existence and multiplicity of nontrivial solutions to the modified
Kirchhoff equation without the growth and Ambrosetti–Rabinowitz conditions
Authors: Wang Zhongxiang , Jia Gao 
Published: October 2021

The paper focuses on the modified Kirchhoff equation \begin{align*}	-\left(a+b\int_{\mathbb{R}^N}|\nabla u|^2dx\right)\Delta u-u\Delta	(u^2)+V(x)u=\lambda f(u), \quad x\in \mathbb{R}^N, \end{align*} where	$a,b&gt;0$, $V(x)\in C(\mathbb{R}^N,\mathbb{R})$ and $\lambda&lt;1$ is a	positive parameter. We just assume that the nonlinearity $f(t)$ is	continuous and superlinear in a neighborhood of $t = 0$
and at infinity. By applying the perturbation method and using the cutoff function, we get
existence and multiplicity of nontrivial solutions to the revised equation.
Then we use the Moser iteration to obtain existence and multiplicity of
nontrivial solutions to the above original Kirchhoff equation. Moreover,
the nonlinearity f(t) may be supercritical.
Towards Export-Led Growth in the West Africa Sub Region Economies
Authors: Ayeni R. K. , FANNEH Momodou Mustapha 
Published: October 2021

The policy of import substitution dominated developing economies especially Sub-Sharan African countries up till 1970. The focus later shifted to pursuing growth through increased export. Recently, countries of the West Africa Sub-region are clamoring for a revisit of growth through import substitution policies. This study therefore delved into the question of whether ECOWAS countries should go for import substitution growth strategy, or to develop strategy that promotes export-led growth, following the law of comparative advantage or a considerable mix of the two strategies. Using an export-augmented neoclassical production function, the study tested how relevant is the Export-led Growth Hypothesis for the ECOWAS sub-region over the period 1980-2014.
Evidence does not offer a strong support for the Hypothesis in the short run but a strong evidence for improved capital stock and labor causing growth. However, long-run results suggest a significant relationship between export and growth but currently negative. A likely explanation of this negativity is that although exports, in the West African sub-regions has the tendency of increasing growth in the long run along with other factors of production, the present conditions of export, especially manufactured and agricultural exports, is experiencing a kind of “Import surge”. That is the import content of exports is high and the local content is low, thus reducing the spillover or multiplier effects. This was confirmed by the strong bilateral causality between export and import discovered in this study. A policy mix of import substitution and export promotion strategies was recommended for countries in this sub-region. Policies that will promote technological innovation in manufacturing and linkages with local suppliers alongside incentives to produce towards export are imperative. Production towards export should be focused on manufactured and agricultural products where each country has the highest comparative advantage so as to reduce the import content of the export.
" State of Knowledge of CSR Practice in Mining Companies in Africa "
Authors: Karambiri Ganabo Lacina 
Published: October 2021

This work is inspired by a number of observations or knowledge. Africa is rich in natural resources exploited by mining companies whose impact is damaging. The question of Corporate Social Responsibility (CSR) in the region therefore arises acutely. The reflection on CSR practice in mining companies in Africa allows to have a better visibility of the activity and the state of the existing texts, laws, standards, directives and principles which frame it. African countries implementing the EITI principles must publish annual reports on the status of revenue and payments of taxes, licenses and fees to local governments and the State. The application of international, regional and national instruments makes it possible to better organize the activity, and to formalize the responsibility of the miners in order to instill the development desired by the populations. Of the many possible determinants of responsible action, the authors describe the role that the network can play in managerial learning.
The Strategic Management Process for Innovation Activities of OMAN Telecommunication Company (OMANTEL)
Authors: Al Abri Sultan 
Published: October 2021

This research will investigate on the strategic management process of the entrepreneurship and innovation activities of Oman Telecommunication Company (OMANTEL). It will assess the chosen organization’s (Omantel) characteristic that is facilitating innovative process, implement activities that establishes an innovative environment within the structure of an organisation and analyse the strategic approach of the company’s innovation management. Moreso, this will also outline a discussion on the dynamics and characteristics of Omantel company and how the ICV policy could be improved; and will analyse as well the strategic management process adopted by Omantel company in driving entrepreneurship and innovation. To achieve these objectives, the relevant sources of information to be utilized include online articles, books and relevant entrepreneurship, innovation and SME journals. Finally, recommendations were made to improve the organization’s innovation process; foremost of which is a program that would provide new skills and knowledge to employees to foster creativity and innovation across organization.