bluuebunny/crossref_metadata_2025_split huggingface dataset:
Similar surgical outcomes of the growing rod technique for treatment of early-onset scoliosis with versus without untreated intraspinal anomalies
Authors: Ma Hongru , Shi Benlong , Li Yang , Liu Dun , Liu Zhen , Sun Xu , Qiu Yong , Zhu Zezhang 
Published: March 2021

OBJECTIVE
The aim of this study was to compare the radiological and clinical outcomes of early-onset scoliosis (EOS) patients with or without intraspinal anomalies (IAs) managed with growing rods (GRs), and to evaluate the safety of the GR technique in EOS patients with untreated IAs.

METHODS
EOS patients undergoing GR placement between August 2008 and July 2017 were retrospectively reviewed. Patients with untreated IAs were classified into the EOS+IA group, and those without IAs into the EOS−IA group. The radiographic parameters including Cobb angle of the major curve, T1–S1 height, and apical vertebral translation were measured, and a detailed assessment of the neurological status was performed at each visit.

RESULTS
Seventy-six patients with EOS (32 boys, 44 girls) with an average age of 6.5 ± 2.3 years at initial surgery satisfied the inclusion and exclusion criteria, including 28 patients in the EOS+IA group and 48 patients in the EOS−IA group. The radiographic measurements were comparable between groups preoperatively, postoperatively, and at the latest follow-up. One patient in the EOS+IA group experienced sensory deficit in a unilateral lower extremity after initial surgery, and an intraoperative neurophysiological monitoring event was observed in a patient in the EOS−IA group. No permanent neurological deficit was observed in either group.

CONCLUSIONS
EOS patients with and those without IAs had comparable clinical and radiological outcomes of the GR technique. Repeated lengthening procedures may be safe for EOS patients with untreated IAs.
Prenatal ventriculomegaly: natural course, survival, and neurodevelopmental status
Authors: Kheiri Ghazaleh , Naderian Negin , Karami Sajedeh , Habibi Zohreh , Nejat Farideh 
Published: March 2021

OBJECTIVE
Prenatal ventriculomegaly is classified as mild, moderate, or severe based on the atrium diameter. The natural course and intrauterine progression of mild and moderate ventriculomegaly associated with the neurodevelopmental status of these children has been widely reported.

METHODS
One hundred twenty-two pregnancies with mild and moderate ventriculomegaly referred to the pediatric neurosurgery clinic of Children’s Medical Center between 2010 and 2018 were retrospectively studied. The authors collected demographic and first and sequential ultrasonographic information, associated abnormalities, information about pregnancy outcomes, and the latest developmental status of these children according to Centers for Disease Control and Prevention criteria by calling parents at least 1 year after birth.

RESULTS
The mean gestational age at the time of diagnosis was 29.1 weeks, and 53% of fetuses were female. The width of the atrium was registered precisely in 106 cases, in which 61% had mild and 39% had moderate ventriculomegaly. Information on serial ultrasound scans was collected in 84 cases in which ventriculomegaly regressed in 5, remained stable in 67, and progressed in 12 patients. Fourteen cases (29.7%) in the mild ventriculomegaly group and 6 cases (16.2%) in the moderate group had associated abnormalities, with corpus callosum agenesis as the most frequent abnormality. The survival rate was 80% in mild and 89.4% in moderate ventriculomegaly. Considering survival to live birth and progression of the ventriculomegaly, the survival rate was 100% in regressed, 97% in stable, and 41.6% in progressed ventricular width groups (p < 0.001). Neurodevelopmental status was evaluated in 73 cases and found to be normal in 69.8% of the cases; 16.4% of children had mild delay, and 5.4% and 8.2% of cases were diagnosed with moderate and severe delays, respectively.

CONCLUSIONS
In spite of a high rate of missed data in our retrospective study, most patients with mild or moderate ventriculomegaly had a stable or regressed course. Most cases had near-normal developmental status. Prospective studies with a larger sample size and detailed developmental evaluation tests are needed to answer the questions related to the natural course, survival, and prognosis of prenatal ventriculomegaly.
Del relato mínimo a la narración aumentada: algunos ejemplos en el microrrelato español actual
Authors: Bustamante Valbuena Leticia 
Published: March 2021

En los primeros años del siglo XXI, el microrrelato se ha convertido en claro exponente de la narrativa híbrida, multiplataforma, hipermedial y transmediática. Estos fenómenos se manifiestan en diversos soportes y se difunden por medios de comunicación analógicos y digitales, aunque actualmente estos últimos ocupen un lugar destacado. El peculiar recorrido de algunos microrrelatos españoles contemporáneos puede demostrar cómo los principales rasgos definidores de este género –mundo referencial complejo, virtualidad narrativa y brevedad textual extrema- propician estas transformaciones. Además de constatar las mutaciones sufridas por estos textos en su periplo multiplataforma, al cotejar su análisis desde la teoría del microrrelato con las interpretaciones semióticas de los códigos que se combinan, se llegará a conclusiones reveladoras. Todos los planos del relato se verán comprometidos: se dotará de sentidos unívocos a indicios de la elipsis discursiva, se concretarán incertidumbres y vacíos intencionados en el plano de la historia y las referencias serán más directas. La duda fundamental es si realmente estamos ante la transformación de relatos mínimos de discurso brevísimo en narraciones aumentadas o si, por el contrario, el resultado coarta el poder de sugerencia, intrínseco al género).
Aspectos retóricos en el microrrelato hispánico
Authors: Garribba Aviva 
Published: March 2021

A pesar de que en ocasiones se ve la retórica como algo opuesto a la austeridad y esencialidad propia del microrrelato, el arte del bien decir tiene en realidad un papel esencial, pues algunas figuras retóricas resultan ser muy propias de este género y son empleadas justamente para alcanzar el resultado de un texto sumamente compacto y a la vez de efecto contundente.
Se analizan algunos aspectos del papel de la retórica en el microrrelato hispánico actual a través de los textos publicados en dos antologías recientes. Se describen las figuras retóricas más frecuentes y relevantes, su función y su posición en el texto.
Les saisons de Cy Twombly, à la lumière de Renoir
Authors: Mitjans Puebla Marta 
Published: March 2021

Cet article porte sur l’analyse iconographique de Four seasons (1993), par l’artiste contemporain Edwin Parker “Cy Twombly” (Cy Twombly, 1928 – 2011), à la lumière de deux créations du maître impressionniste Pierre-Auguste Renoir (1845 – 1919). La vague (1879) et Paysage bords de Seine (1879) sont deux œuvres où Renoir imprime un sceau qui capte l’éphémère à travers la couleur, le mouvement de la lumière et le pleinairisme. Four seasons est une œuvre qui ne peut pas être comprise comme création contemporaine sans étudier l’empreinte de Renoir dans l’abstraction lyrique américaine ̶ un sceau visible dans la technique, l’usage de la couleur, la thématique et le message de la création. Le besoin de saisir l’harmonie, à travers une création dans laquelle l’image et le texte se mêlent, représente l’évolution de la même œuvre de Renoir dans la contemporanéité : une création où le message unit image et langage, voire un poème visuel.
Alteration of m6A RNA Methylation in Heart Failure With Preserved Ejection Fraction
Authors: Zhang Beijian , Xu Yamei , Cui Xiaotong , Jiang Hao , Luo Wei , Weng Xinyu , Wang Yun , Zhao Yuhong , Sun Aijun , Ge Junbo 
Published: March 2021

Background: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous disease, in which its pathogenesis is very complex and far from defined. Here, we explored the N6-methyladenosine (m6A) RNA methylation alteration in patients with HFpEF and mouse model of HFpEF.Methods: In this case–control study, peripheral blood mononuclear cells (PBMCs) were separated from peripheral blood samples obtained from 16 HFpEF patients and 24 healthy controls. The change of m6A regulators was detected by quantitative real-time PCR (RT-PCR). A “two-hit” mouse model of HFpEF was induced by a high-fat diet and drinking water with 0.5 g/L of Nω-nitro-l-arginine methyl ester (L-NAME). MeRIP-seq was used to map transcriptome-wide m6A in control mice and HFpEF mice, and the gene expression was high-throughput detected by RNA-seq.Results: The expression of m6A writers METTL3, METTL4, and KIAA1429; m6A eraser FTO; and reader YTHDF2 was up-regulated in HFpEF patients, compared with health controls. Furthermore, the expression of FTO was also elevated in HFpEF mice. A total of 661 m6A peaks were significantly changed by MeRIP-seq. Gene Ontology (GO) analysis revealed that protein folding, ubiquitin-dependent ERAD pathway, and positive regulation of RNA polymerase II were the three most significantly altered biological processes in HFpEF. The pathways including proteasome, protein processing in the endoplasmic reticulum, and PI3K-Akt signaling pathway were significantly changed in HFpEF by Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis.Conclusions: The expression pattern of m6A regulators and m6A landscape is changed in HFpEF. This uncovers a new transcription-independent mechanism of translation regulation. Therefore, our data suggest that the modulation of epitranscriptomic processes, such as m6A methylation, might be an interesting target for therapeutic interventions.
Classification of Metastatic and Non-Metastatic Thoracic Lymph Nodes in Lung Cancer Patients Based on Dielectric Properties Using Adaptive Probabilistic Neural Networks
Authors: Lu Di , Yu Hongfeng , Wang Zhizhi , Chen Zhiming , Fan Jiayang , Liu Xiguang , Zhai Jianxue , Wu Hua , Yu Xuefei , Cai Kaican 
Published: March 2021

ObjectiveDielectric properties can be used in normal and malignant tissue identification, which requires an effective classifier because of the high throughput nature of the data. With easy training and fast convergence, probabilistic neural networks (PNNs) are widely applied in pattern classification problems. This study aims to propose a classifier to identify metastatic and non-metastatic thoracic lymph nodes in lung cancer patients based on dielectric properties.MethodsThe dielectric properties (permittivity and conductivity) of lymph nodes were measured using an open-ended coaxial probe. The Synthetic Minority Oversampling Technique method was adopted to modify the dataset. Feature parameters were scored to select the appropriate feature vector using a Statistical Dependency algorithm. The dataset was classified using adaptive PNNs with an optimized smooth factor using the simulated annealing PNN (SA-PNN). The results were compared with traditional Probabilistic, Support Vector Machines, k-Nearest Neighbor and the Classify functions in MATLAB.ResultsThe conductivity frequencies of 3959, 3958, 3960, 3978, 3510, 3889, 3888, and 3976 MHz were selected as the feature vectors for 219 lymph nodes (178 non-metastatic and 41 metastatic). Compared with the other methods, SA-PNN achieved the highest classification accuracy (92.92%) and the corresponding specificity and sensitivity were 94.72% and 91.11%, respectively.ConclusionsCompared with the other methods, the SA-PNN proposed in the present study achieved a higher classification accuracy, which provides a new scheme for classification of metastatic and non-metastatic thoracic lymph nodes in lung cancer patients based on dielectric properties.
Effects of Interleukin-1β in Glycinergic Transmission at the Central Amygdala
Authors: Solorza Jocelyn , Oliva Carolina A. , Castillo Karen , Amestica Gabriela , Maldifassi María Constanza , López-Cortés Xaviera A. , Barra Rafael , Stehberg Jimmy , Piesche Matthias , Sáez-Briones Patricio , González Wendy , Arenas-Salinas Mauricio , Mariqueo Trinidad A. 
Published: March 2021

Interleukin-1β (IL-1β) is an important cytokine that modulates peripheral and central pain sensitization at the spinal level. Among its effects, it increases spinal cord excitability by reducing inhibitory Glycinergic and GABAergic neurotransmission. In the brain, IL-1β is released by glial cells in regions associated with pain processing during neuropathic pain. It also has important roles in neuroinflammation and in regulating NMDA receptor activity required for learning and memory. The modulation of glycine-mediated inhibitory activity via IL-1β may play a critical role in the perception of different levels of pain. The central nucleus of the amygdala (CeA) participates in receiving and processing pain information. Interestingly, this nucleus is enriched in the regulatory auxiliary glycine receptor (GlyR) β subunit (βGlyR); however, no studies have evaluated the effect of IL-1β on glycinergic neurotransmission in the brain. Hence, we hypothesized that IL-1β may modulate GlyR-mediated inhibitory activity via interactions with the βGlyR subunit. Our results show that the application of IL-1β (10 ng/ml) to CeA brain slices has a biphasic effect; transiently increases and then reduces sIPSC amplitude of CeA glycinergic currents. Additionally, we performed molecular docking, site-directed mutagenesis, and whole-cell voltage-clamp electrophysiological experiments in HEK cells transfected with GlyRs containing different GlyR subunits. These data indicate that IL-1β modulates GlyR activity by establishing hydrogen bonds with at least one key amino acid residue located in the back of the loop C at the ECD domain of the βGlyR subunit. The present results suggest that IL-1β in the CeA controls glycinergic neurotransmission, possibly via interactions with the βGlyR subunit. This effect could be relevant for understanding how IL-1β released by glia modulates central processing of pain, learning and memory, and is involved in neuroinflammation.
Association Between Commute Duration and Sickness Absence in the Context of China: Mechanism and Heterogeneous Effects
Authors: Wang Zicheng , Wu Qiushi , Guo Murong 
Published: March 2021

Background:Most employees in urban China have experienced a heavy commuting burden, which has become an urgent issue that should be solved in the new urbanization strategy process. However, the exploration of the relationship between the commute duration and sickness absence remains scant in China, and no direct discussion has been done to analyze the mechanism linking commute duration and sickness absence.Methods:Using a unique dataset of the 2013 China Matched Employer–Employee Survey, the present study applies a two-level random-intercept Poisson model to explore this association.Results:A long commute is significantly related with increased sickness absence. A longer commute is associated with poorer self-rated health status and a higher degree of psychological depression, and it is also highly related with a decrease in sleeping time. Moreover, an increased commuting duration is associated with lower work effort (working hours).Conclusion:Longer commute duration induces lower productivity through increased sickness absence, and the potential link of commute duration and sickness absence is mainly transmitted through health-related outcomes and work effort.
Elastic constant of dielectric nano-thin films using three-layer resonance studied by picosecond ultrasonics
Authors: Fukuda Hiroki , Nagakubo Akira , Ogi Hirotsugu 
Published: March 2021

Abstract
Elastic constants and sound velocities of nm order thin films are essential for designing acoustic filters. However, it is difficult to measure them for dielectric thin films. In this study, we use a three-layer structure where a dielectric nano-thin film is sandwiched between thicker metallic films to measure the longitudinal elastic constant of the dielectric film. We propose an efficiency function to estimate the optimal thicknesses of the components. We use Pt/NiO/Pt three-layer films for confirming our proposed method. The determined elastic constant of NiO deposited at room temperature is smaller than the bulk value by ∼40%. However, it approaches the bulk value as the deposition temperature increases. We also reveal that the uncertainty of the elastic constant of the Pt film insignificantly affects the accuracy of the determined elastic constant of NiO in this structure.
Improvement of self-heating effect in Ge vertically stacked GAA nanowire pMOSFET by utilizing Al2O3 for high-performance logic device and electrical/thermal co-design
Authors: Song Young Suh , Kim Sangwan , Kim Garam , Kim Hyunwoo , Lee Jong-Ho , Kim Jang Hyun , Park Byung-Gook 
Published: March 2021

Abstract
For improving self-heating effect (SHE) in Ge vertically stacked gate-all-around (GAA) nanowire (NW) p-type metal-oxide-semiconductor field-effect transistor (pMOSFET), aluminum oxide (Al2O3, alumina) is utilized for gate dielectric layer. From the high thermal conductivity of Al2O3, SHE is significantly improved. In order to validate the proposed device structure, technology computer-aided design simulation is performed through Synopsys Sentaurus three-dimensional tool. As a result, when Al2O3 is incorporated in Ge vertically stacked GAA NW pMOSFET, SHE can be remarkably improved from 534 to 419 K. In addition, the method of simultaneously accomplishing improvement of SHE and low gate leakage current (I
gate) have been specifically investigated and proposed with numerous simulation data.
PERBANDINGAN METODE DEMPSTER SHAFER DAN CERTAINTY FACTOR UNTUK DIAGNOSIS PENYAKIT TANAMAN TERONG (Studi Kasus Dusun Kejoren, Desa Gerbo, Kec. Purwodadi)
Authors: Basri Mohammad Hasan , Mahmudi Ali , Vendyansyah Nurlaily 
Published: March 2021

Permasalahan yang dihadapi oleh para petani tanaman terong di Dusun Kejoren, Desa Gerbo Kecamatan Purwodadi adalah kerusakan tanaman terong yang disebabkan oleh serangan penyakit. Para petani sering mengalami kerugian pada musim panen, karena tanamanya mati terserang penyakit. Penyakit tersebut biasanya menyerang tanaman petani pada musim penghujan, sehingga tingkat kegagalan panen pada musim penghujan sangat tinggi. Kurangnya pengetahuan petani tentang penyakit dan cara menanggulangi menjadi penyebab dari tanaman terong mudah terserang penyakit.
Pada penelitian ini menggunakan metode Dempster Shafer dan Certainty Factor untuk membangun sistem pakar diagnosis penyakit tanaman terong. Data yang digunakan pada penelitian ini berupa data gejala, data penyakit, dan data solusi pengendalian yang didapatkan dari Balai Pengkajian Teknologi Pertanian Jawa Timur (BPTP), dan divalidasi oleh pakar yang ahli dalam bidang pertaniann.
Berdasarkan hasil pengujian dilakukan oleh 1 orang pakar didapatkan presentase setuju 70% dan kurang setuju 30%. Pengujian keakuratan perhitungan pada sistem dan perhitungan perhitungan manual dan didapatkan nilai presentase rata – rata error sebesar 3,65%. Dan metode yang lebih baik antara metode Dempster shafer dan Certainty Factor adalah metode Dempster-Shafer dengan nilai presentase hasil diagnosis yang sama dengan pakar sebesar 80%.
Kata kunci : Sistem Pakar, Terong, Dempster shafer, Certainty Factor.
RANCANG BANGUN ROBOT SAR SEBAGAI PENDETEKSI GAS BERACUN PRA EVAKUASI
Authors: Renaldi Bima , Adi Wibowo Suryo , Auliasari Karina 
Published: March 2021

Penelitian ini dilakukan untuk membuat dan merancang sebuah robot SAR sebagai pendeteksi gas beracun pra evakuasi untuk memeriksa keadaan pada tempat yang akan dilaksanakan evakuasi untuk keamanan dari tim penyelamat dan memperoleh infomasi terbaru dari tempat kejadian. Hal ini juga bertujuan untuk meminimalisir jatuhnya korban pra evakuasi seperti pada Tim SAR ataupun tim penyelamat lainnya khususnya diwilayah urban atau perkotaan. Robot pendeteksi gas ini dapat melakukan atau menampilkan hasil monitoring dari kadar kandungan gas disekitarnya lewat website. Disamping itu dengan kontrol yang bisa dilakukan lewat website akan membuat sistem robot menjadi lebih efisien dan efektif. Dari Hasil pengujian menunjukkan bahwa sensor diketahui memiliki rata-rata persentase error pada sensor MQ-7 sebesar 6,54%, Sensor MQ-135 sebesar 19,08% untuk deteksi gas Amonia dan 3,16% untuk Karbon Dioksida, serta 9,83% untuk sensor ultrasonic. . Jarak terjauh flame sensor untuk mendeteksi api secara optimal yaitu pada jarak 80cm dengan nilai voltage 1.74v dan tidak dapat lagi pendeteksi api pada jarak 84cm dengan nilai voltage 2.03v Robot SAR dapat beroperasi optimal selama 40 Menit. Website berjalan dengan baik pada beberapa web browser yang diujikan yaitu Mozila Firefox (47.0.2), Google Chrome (78.0.3) dan Microsoft Edge (44.1.0) karena aplikasi merupakan website responsive yang dibuat menggunakan pemrograman PHP. Metode Fuzzy Tsukamoto dapat berjalan dengan baik dan akurat pada sistem dengan rata – rata persentase error 0%.
PENERAPAN METODE SIMPLE ADDITIVE WEIGHTING UNTUK MENENTUKAN SISWA KURANG BERPRESTASI PADA JENJANG SEKOLAH DASAR BERBASIS WEB
Authors: Cahya Kusuma Firdaus Dwi , Achmadi Sentot , Wibowo Suryo Adi 
Published: March 2021

Guru menyadari bahwa setiap siswa pastinya memiliki kemampuan yang berbeda-beda dalam menangkap materi yang diberikan pada saat kegiatan belajar mengajar dilaksanakan. apabila permasalahan tersebut tidak segera ditangani lama kelamaan dapat mempengaruhi tingkat kecerdasan masing-masing siswa. Oleh karena itu dibuatlah sistem untuk menentukan siswa kurang berprestasi agar guru dapat mengetahui dengan cepat kemampuan masing-masing siswa pada setiap mata pelajaran. Dalam pelakasanaannya sistem yang dibuat mempertimbangkan lima aspek kriteria penilaian dantaranya Nilai Ulangan Harian, Nilai Ujian Tengah Semester, Nilai Ujian Akhir Semester, serta Nilai Praktek dan Produk.
Sistem Pendukung Keputusan ini dibuat dengan menggunakan metode Simple Additive Weighting ( SAW ), yaitu mencari penjumlahan terbobot dari rating kinerja pada setiap alternatif pada semua atribut dengan proses normalisasi matriks keputusan (X) ke suatu skala yang dapat diperbandingkan dengan semua rating alternatif yang ada.
Dengan adanya Sistem Pendukung Keputusan ini dapat menjadi solusi bagi guru SDN Wedoro dalam menentukan siswa yang kurang berprestasi agar memperoleh perhatian khusus untuk meningkatkan prestasinya. Dan hasil pengujian dari penelitian ini berupa daftar sepuluh siswa kurang berprestasi di masing-masing pelajaran dalam satu semester, dengan tingkat akurasi sistem dalam menentukan siswa kurang berprestasi sebesar 80%.
PENGENALAN TOOLS KESELAMATAN KERJA MENGGUNAKAN AUGMENTED REALITY BERBASIS ANDROID
Authors: Suandi Suandi , Adi Wibowo Suryo , Auliasari Karina 
Published: March 2021

Kecelakaan kerja merupakan suatu kejadian yang sering sekali terjadi di tempat kerja. Kecelakaan kerja bisa menyebabkan pekerja mengalami luka-luka bahkan meninggal dunia. Masalah kecelakaan kerja di Indonesia masih tergolong tinggi. Menurut Bpjs Ketenagakerjaan (2019) terjadi kecenderungan kecelakaan kerja. Pada tahun 2016 terdapat 105.182 kasus kecelakaan kerja, tahun 2017 terdapat 123.041 kasus dan tahun 2018 terdapat 173.105 kasus.
Di era teknologi saat ini sudah hadir teknologi Augmented Reality (AR). Teknologi Augmented Reality (AR) merupakan teknologi yang dapat menggabungkan dunia maya dan nyata secara real time dan diproyeksikan menggunakan elektronik. Teknologi Augmented Reality (AR) dimanfaatkan dalam pembuatan aplikasi pengenalan tools keselamatan kerja menggunakan metode marker based tracking. Marker merupakan image target untuk mengenali dan menampilkan objek serta informasi yang terdapat didalam objek.
Hasil dari penelitian ini berupa aplikasi pengenalan tools keselamatan kerja. Tujuan pembuatan aplikasi ini yaitu untuk membantu para pekerja lebih mengetahui tools keselamatan kerja apa saja yang dibutuhkan saat bekerja sehingga dapat mengurangi angka kecelakaan kerja di Indonesia. Aplikasi pengenalan tools keselamatan kerja bisa menampilkan objek 3D alat keselamatan kerja dan rambu-rambu keselamatan kerja serta penjelasannya menggunakan audio dan narasi.