bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERAN KONSELOR DALAM PENANAMAN PENDIDIKAN ANTIKORUPSI BAGI SISWA SMPN 5 KEPANJEN
Authors: Abdi S Fairus 
Published: February 2021

Abstract: Corruption comes from the Latin "corruputio" or "corruptus" meaning damage or corruption (Samidan, 2011). Meaning of the word corruption is corruption, literally, malice, depravity, dishonesty, can be bribed, immoral, deviations from the Holiness (Karsona, 2013). Corruption may be defined as a misappropriation or misuse of State money and private for personal benefit or others. The Act of corruption can also damage a country in terms of economy and education. Corruption in Indonesia is already very worrying, and needs to be eradicated altogether, during the handling of the corruption eradication more done in the form of repressive actions, namely the Act provides punishment by holding the corruptor. Other strategies in the fight against corruption, one of them with preventive action or prevention of the occurrence of corruption, this action which is considered the most effective way to prevent the occurrence of corruption, namely through education pathways. This type of research is a case study, Bungin (2003) describes research case study is a study that is comprehensive, intensive, detailed and insightful as well as more directed in an effort to elucidate the issues or phenomena the contemporary nature and immediacy. Anti-corruption education modules can be delivered through the role of the Counselor/teacher BK through granting information services by delivering anti-corruption education values for students of JUNIOR HIGH SCHOOL. Anti-corruption education could be developed back-related media provided against the students.
Keywords: Anti-corruption Education, Counselors, Students
PENGEMBANGAN PANDUAN PERMAINAN TRADISIONAL BENTENG UNTUK MENINGKATKAN KECERDASAN EMOSIONAL SISWA SDN LAWANGAN DAYA PAMEKASAN
Authors: Ishlakhatus Sa’idah Ziyadul Haq Annajih, 
Published: February 2021

Penelitian ini bertujuan untuk mengembangkan panduan permainan tradisional benteng sebagai media dalam meningkatkan kecerdasan emosional siswa. Pengembangan panduan permainan tradisional benteng sebagai media untuk meningkatkan kecerdasan emosional siswa, peneliti menggunakan prosedur penelitian dan pengembangan R&D (research and development) Borg & Gall. Efektifitas produk panduan permainan benteng berdasarkan kesesuaian produk terhadap karakteristik pengguna, yaitusiswa kelas VI SD dan juga kesesuaian produk dengan indikator perkembangan kecerdasan emosional siswa. Hal ini dapat dilihat dari hasil pengamatan sebelum dan sesudah menggunakan panduan permainan tradisional benteng. Hasil uji keefektifan produk panduan permainan tradisional benteng adalah nilai t hitung > t tabel (4.827 > 2.160) sehingga penggunaan produk panduan permainan tradisional benteng efektif dalam meningkatkan kecerdasan emosional.
From Reading to Writing Argumentative Texts: Strategies as a Bridge
Authors: Dallagi Maha 
Published: February 2021

Reading and Writing differ in accordance with the position of the learner and depend on the process of retrieving ideas from the text or formulating ideas into a written text. Reading process becomes a writing process when it turns from a receptive skill into a productive one. Wittrock (1989, p. 347) explains that “These well-known differences are summarized best by the commonly accepted belief that writing is the process of putting meaning on written pages, whereas reading is the process of getting meaning from the written pages”. Nevertheless, and despite the different aspects of the two skills, a large and growing body of the literature has investigated and highlighted the existence of common points and the conversion from Reading to Writing. This paper investigated the conversion of Receptive strategies into productive strategies in the writing of argumentative essays by 147 Tunisian University students. Results revealed the strong connection of the two sets of strategies and recommends teachers to raise students’ awareness of the latter to enhance their proficiency level. The aim of this study was to assess the relationship and connection between Reading and Writing in English as a Foreign Language context, and more particularly in the Tunisian University Setting. This study argues in favor of focusing on that connection while teaching Reading and Writing argumentative texts to non-native speakers.
Виявлення впливу акторів горизонтального рівня на стан економічної безпеки інтегрованої промислової структури на основі оцінки фінансової складової
Authors: Христенко Л.М. , Чорна О.Ю. , Білоус Я.Ю. 
Published: February 2021

У статті розкрито зміст поняття «економічна безпека інтегрованої промислової структури»; доведена значущість фінансової складової як функціонального елементу у структурі системи економічної безпеки інтегрованої промислової структури та її акторів, оцінка якої дозволить оперативно встановити фактичний стан економічної безпеки інтегрованої промислової структури й виявити напрями його зміни під впливом станів акторів; запропонована методика виявлення впливу акторів горизонтального рівня на стан економічної безпеки інтегрованої промислової структури через визначення відправної позиції та змін у зонах ризиків діяльності інтегрованої промислової структури та її акторів за оцінками швидких показників-індикаторів фінансової складової; проведено апробацію запропонованої методики на прикладі інтегрованої промислової структури – ТОВ «Метінвест Холдинг».
Проблематика ототожнення інтелектуальної та розумової праці
Authors: Крамчанінова М.Д. , Касаткіна М.В. , Лєдовська A.I. 
Published: February 2021

У статті розглянута змістовна сутність розумової та інтелектуальної праці. На основі науково-інформативної бази авторами зроблена спроба критичного аналізу різних підходів до розуміння феномену інтелектуальної праці, а також узагальнення ряду її специфічних характеристик і критеріїв.Інтелектуальну працю розглянуто як якісно новий вид трудової діяльності, що має у своїй основі творчу працю та новації як результат.В ході дослідження авторами визначено фактори, що впливають на психофізіологічні показники індивідуумав процесі здійснення їм інтелектуальної діяльності. Також наведено класифікацію складових інтелектуальної праці на основі обліку видів інтелектуальної діяльності. Результати дослідження актуальної проблеми ототожнення інтелектуальної праці з розумовою, дозволили обґрунтувати необхідність її відокремлення. Що обумовлено значною сутнісною відмінністю інтелектуальної праці та її специфікою, яка вимагає зміни існуючих підходів до нормування та пошуку нових, більш нетрадиційних способів вимірювання продуктивності творчої діяльності.
Стратегії міжнародного маркетингу транснаціональних корпорацій в умовах глобалізації
Authors: Птащенко О.В. , Кущ Я.М. 
Published: February 2021

У статті розглянуто основні маркетингові стратегії транснаціональних корпорацій в умовах глобалізації, а також їх вплив на міжнародну торгівлю та концепцію міжнародного маркетингу.
Сучасний процес глобалізації світової економіки в цілому вимагає постійного розвитку та вдосконалення бізнес-стратегій.
Головною метою транснаціональної корпорації на міжнародному ринку виступає пошук та максимальне збільшення прибутку, який корпорація отримує від своєї діяльності на національний ринках.
Досить зрозумілим є той факт, що специфіку маркетингу транснаціональної корпорації можна пояснити специфікою діяльності ТНК. Особливості маркетингу транснаціональної корпорації полягають у необхідності централізувати маркетингову діяльність на різних локальних та національних ринках, а також координувати цю діяльність по всьому світу. Це пояснює важливість розробки маркетингової стратегії для транснаціональних корпорацій.
La radio en el ecosistema mediático del siglo XXI: estudio de caso en Portugal
Authors: Canavilhas João 
Published: February 2021

Desde que aparece la televisión, la muerte de la radio se anuncia como cercana. A pesar de todas las amenazas, el medio continúa vivo e, incluso, gana nuevos públicos en un escenario hostil para un medio centenario. La realidad muestra que la radio transformó sus debilidades en fuerzas y se adecuó al nuevo ecosistema de una forma más rápida que cualquier otro medio. Las razones de esta veloz y exitosa adaptación están relacionadas con la simplicidad del soporte y con el lenguaje unisensorial usado, pero también con una capacidad inaudita para el reajuste a nuevas situaciones. En este trabajo se identifican los rasgos que hacen de la radio una superviviente y se analiza la forma como se adaptó al nuevo ecosistema, ilustrando cada caso con ejemplos de programas radiofónicos portugueses.
The Cancer-Testis Long Non-coding RNA PCAT6 Facilitates the Malignant Phenotype of Ovarian Cancer by Sponging miR-143-3p
Authors: Tan Xiaofang , Shao Yang , Teng Yue , Liu Siyu , Li Weijian , Xue Lu , Cao Yuepeng , Sun Chongqi , Zhang Jinhong , Han Jing , Wu Xiaoli , Xu Hanzi , Xie Kaipeng 
Published: February 2021

Background: It has been reported that long non-coding RNAs (lncRNAs) play critical roles in tumorigenesis. However, their roles in ovarian cancer (OC) remain to be elucidated. The aim of this study was to uncover the function and underlying mechanisms of PCAT6 in OC.Methods: The expression pattern of PCAT6 in OC was analyzed in the GSE137238, GSE143897 and Gene Expression Profile Interactive Analysis (GEPIA) datasets. Kaplan–Meier Plotter online software was used for survival analysis. Loss-of-function assays and gain-of-function assays were used to assess the function of PCAT6 in OC development. Moreover, small-RNA sequencing, bioinformatic analysis, luciferase assays and rescue experiments were carried out to clarify the potential mechanism of PCAT6 in OC.Results: PCAT6 expression was significantly increased in OC tissues and positively correlated with advanced stages and with poor overall survival, progression-free survival and post-progression survival. Knockdown of PCAT6 in A2780 and SKOV3 cells inhibited OC cell proliferation, migration and invasion. In contrast, Overexpression of PCAT6 exerted the opposite effects on OC cells. Notably, PCAT6 bound to miR-143-3p and affected the expression of transforming growth factor (TGF)-β-activated kinase 1 (TAK1). Subsequent rescue assays confirmed that upregulation of miR-143-3p decreased the PCAT6 overexpression-induced promotion of proliferation, migration and invasion. Moreover, downregulation of miR-143-3p reversed the PCAT6 knockdown-induced inhibition of proliferation, migration, and invasion.Conclusions: Our findings demonstrate that PCAT6 plays an oncogenic role in OC and may be useful as a therapeutic target for OC.
Modeling a Sustainable, Self-Energized Pine Dust Pyrolysis System With Staged Condensation for Optimal Recovery of Bio-Oil
Authors: Charis Gratitude , Danha Gwiranai , Muzenda Edison , Nhubu Trust 
Published: February 2021

This simulation study explores sustainable improvements that could be made to a pine dust pyrolysis system to eliminate total dependence on external electrical energy supply and improve the yield of high-quality dry bio-oil. The components, stoichiometric yield and composition of oil, char and gas were modeled in ChemCAD using data from literature and results from biomass characterization and pyrolysis. A fast pyrolysis regime was used to increase the overall yield of dry oil fraction recovered and the char by-product was utilized to make the system energy self-sufficient. The optimization study focused on the condensation system whose parameters were varied at the provided optimum pyrolysis temperature. The recommended temperature for the primary condenser was 96–110°C which yielded 23.3–29.8 wt% dry oil with 2.4–4.4 wt% water content. The optimum temperature for the secondary condenser was 82°C whose bio-oil (∼2.92 wt%) had a moisture content of 7.5–10 wt% at constant primary condenser temperature between 96–110°C. The third condenser could be operated at ambient temperature. The results were validated using both information reported in literature and results from the previous experimental study. Such a simple model built by careful selection of the model bio-oil components is useful in estimating the optimal parameters for the biomass pyrolysis staged condensation system.
Outcome Predictors of Biopsy-Proven Myeloperoxidase-Anti-Neutrophil Cytoplasmic Antibody-Associated Glomerulonephritis
Authors: Ge Yifei , Yang Guang , Yu Xiangbao , Sun Bin , Zhang Bo , Yuan Yanggang , Zeng Ming , Wang Ningning , Mao Huijuan , Xing Changying 
Published: February 2021

ObjectiveTo determine the prognostic values of histopathologic classification of myeloperoxidase-anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis and other clinical and laboratory features at the time of presentation on renal and patient survival associated with myeloperoxidase-ANCA-associated glomerulonephritis (MPO-ANCA-GN).MethodsA total of 112 patients diagnosed with MPO-ANCA-GN from October 2005 to December 2018 were enrolled. The baseline clinical characteristics, renal histopathological data, and risk factors predictive of renal and patient survival were retrospectively analyzed.ResultsAll 112 patients underwent renal biopsy. Disease in 32 patients was classified as focal, 26 as mixed, 29 as crescentic, and 25 as sclerotic. Over a median follow-up period of 41.5 months, there were 44 patients dialysis-dependent. The renal survival rate was significantly higher in the focal group than the other groups (p &lt; 0.001) and significantly lower in the sclerotic group (p &lt; 0.05). In addition, disease histopathologically classified as sclerotic (p = 0.044), high serum creatinine level (≥320 μmol/L, p &lt; 0.001), low albumin (&lt;30 g/L, p = 0.024) and hemoglobin level (&lt;90 g/L, p = 0.044) were associated with a greater risk of ESRD. After follow-up, 70 (62.5%) of 112 patients survived. Old age (≥60 years, p = 0.018) and low serum albumin (&lt;30 g/L, p = 0.006) was significant risk factor for patient survival.ConclusionAmong patients with MPO-ANCA-GN, those with poor renal function, disease histopathologically classified as sclerotic, and lower albumin and hemoglobin levels were risk factors for ESRD, while older age and low serum albumin level were associated with a greater risk for all-cause mortality.
Carbon-Based Materials as Catalyst Supports for Fischer–Tropsch Synthesis: A Review
Authors: Valero-Romero María José , Rodríguez-Cano Miguel Ángel , Palomo José , Rodríguez-Mirasol José , Cordero Tomás 
Published: February 2021

The use of carbon-based materials as catalyst supports for Fischer–Tropsch synthesis (FTS) is thoroughly reviewed. The main factors to consider when using a carbonaceous catalyst support for FTS are first discussed. Then, the most relevant and recent literature on the topic from the last 2 decades is reviewed, classifying the different examples according to the carbon structure and shape. Some aspects such as the carbon textural properties, carbon support modification (functionalization and doping), catalyst preparation methods, metal particle size and location, catalyst stability and reducibility, the use of promoters, and the catalyst performance for FTS are summarized and discussed. Finally, the main conclusions, advantages, limitations, and perspectives of using carbon catalyst supports for FTS are outlined.
Risk Factors and Outcomes of Klebsiella pneumoniae Infection Before and After Allogeneic Hematopoietic Cell Transplantation
Authors: Gavriilaki Eleni , Sakellari Ioanna , Chatzikonstantinou Thomas , Mallouri Despina , Batsis Ioannis , Katsifa Eleni , Papadimitriou Stergios , Panteliadou Alkistis , Baldoumi Eirini , Demosthenous Christos , Bousiou Zoi , Constantinou Varnavas , Sotiropoulos Damianos , Anagnostopoulos Achilles 
Published: February 2021

Objectives:Klebsiella pneumoniae carbapenemase (KPC)–producing K. pneumoniae (KPC-Kp) emerge as a major healthcare concern worldwide. Despite the significance of infections before and after allogeneic hematopoietic cell transplantation (alloHCT), the burden of KP infections has not been extensively evaluated.Methods: We studied the incidence, risk factors, and outcomes of consecutive alloHCT recipients with Kp isolates before and after alloHCT.Results: Among 424 patients who underwent alloHCT in 2008–2018, we studied two groups: those with Kp isolates before (group 1, 52 patients) and those with Kp isolates after alloHCT (group 2, 66 patients). prE-transplant infections were associated with post-transplant infections (p = 0.010), despite secondary prophylaxis. KPC-Kp was isolated in 29% of group 1, and 80% of group 2. Both groups were characterized by a significant burden of moderate–severe acute graft- vs.-host disease (GVHD) [cumulative incidence (CI) of 44.5 and 61.9%, respectively] and severe chronic (CI of 56.7 and 61.9%). Kp infections and GVHD were independent predictive factors of treatment-related mortality (TRM) in both groups.Conclusions: Our study highlights the significant impact of Kp infections on TRM, with GVHD consisting an important underlying factor. As prophylactic measures did not improve rates of post-transplant infections, innovative interventions need to be further investigated to address this major healthcare concern.
Early Initiation of Anticoagulation Improves the Long-Term Prognosis in Patients With Antiphospholipid Syndrome Associated Portal Vein Thrombosis
Authors: You Hanxiao , Zhao Jiuliang , Huang Can , Tian Xinping , Li Mengtao , Zeng Xiaofeng 
Published: February 2021

Objectives: Portal vein thrombosis (PVT) is a rare and severe clinical phenotype of antiphospholipid syndrome (APS) with a poor prognosis. Anticoagulation therapy is efficient but is associated with potentially severe bleeding episodes, especially for those patients with thrombocytopenia. We conducted this case-control study to explore the clinical features and associated factors of PVT in APS patients, the re-canalization rate of the PVT after anticoagulation and investigate the beneficial effects of early initiation of anticoagulation in patients with APS associated PVT.Methods: We enrolled patients with APS associated PVT as the case group, and age-, and entry-time-matched APS patients without PVT (1:2) as the control group. We explored the associated factors of PVT in APS patients using multivariate logistic regression analysis. The re-canalization rate of the PVT after anticoagulation was analyzed using the survival analysis.Results: A total of 34 patients (8 males and 26 females) with APS-PVT were enrolled, with a median follow-up time of 3 years (1.5, 7 years). Multivariate logistic regression analysis showed that thrombocytopenia (OR 6.4, 95%CI 1.561–26.218, P = 0.01), hypersensitive c-reactive protein &gt;3 mg/L (OR 4.57, 95%CI 1.426–14.666, P = 0.011), anti β2GPI positive (OR 5, 95%CI 1.816–13.772, P = 0.002) and aPL double-positive (OR 4.08, 95%CI 1.312–12.429, P = 0.013) were independent associated factors for PVT in APS. Survival analysis revealed that effective anticoagulation could increase re-canalization rate significantly (log-rank p = 0.001), with better prognosis (lower mortality rate, log-rank p = 0.045).Conclusions: PVT could be the first presentation of APS with insidious onset and atypical clinical symptoms and easily be misdiagnosed. For patients with APS, double aPLs positive, thrombocytopenia, and inflammation could be the associated factors of PVT. Early diagnosis and anticoagulation treatment can bring thrombus re-canalization thereby significantly improving the prognosis.
Active Surveillance of Asymptomatic, Presymptomatic, and Oligosymptomatic SARS-CoV-2-Infected Individuals in Communities Inhabiting Closed or Semi-closed Institutions
Authors: Ambrosis Nicolás , Martin Aispuro Pablo , Belhart Keila , Bottero Daniela , Crisp Renée Leonor , Dansey María Virginia , Gabrielli Magali , Filevich Oscar , Genoud Valeria , Giordano Alejandra , Lin Min Chih , Lodeiro Anibal , Marceca Felipe , Pregi Nicolás , Lenicov Federico Remes , Rocha-Viegas Luciana , Rudi Erika , Solovey Guillermo , Zurita Eugenia , Pecci Adali , Etchenique Roberto , Hozbor Daniela 
Published: February 2021

Background: The high COVID-19 dissemination rate demands active surveillance to identify asymptomatic, presymptomatic, and oligosymptomatic (APO) SARS-CoV-2-infected individuals. This is of special importance in communities inhabiting closed or semi-closed institutions such as residential care homes, prisons, neuropsychiatric hospitals, etc., where risk people are in close contact. Thus, a pooling approach—where samples are mixed and tested as single pools—is an attractive strategy to rapidly detect APO-infected in these epidemiological scenarios.Materials and Methods: This study was done at different pandemic periods between May 28 and August 31 2020 in 153 closed or semi-closed institutions in the Province of Buenos Aires (Argentina). We setup pooling strategy in two stages: first a pool-testing followed by selective individual-testing according to pool results. Samples included in negative pools were presumed as negative, while samples from positive pools were re-tested individually for positives identification.Results: Sensitivity in 5-sample or 10-sample pools was adequate since only 2 Ct values were increased with regard to single tests on average. Concordance between 5-sample or 10-sample pools and individual-testing was 100% in the Ct ≤ 36. We tested 4,936 APO clinical samples in 822 pools, requiring 86–50% fewer tests in low-to-moderate prevalence settings compared to individual testing.Conclusions: By this strategy we detected three COVID-19 outbreaks at early stages in these institutions, helping to their containment and increasing the likelihood of saving lives in such places where risk groups are concentrated.
Abnormal Expression of Dysferlin in Blood Monocytes Supports Primary Dysferlinopathy in Patients Confirmed by Genetic Analyses
Authors: Zhang Huili , Li Yaqin , Cheng Qiusheng , Chen Xi , Yu Qiuxia , Li Ze 
Published: February 2021

Objective: Dysferlin deficiency causes dysferlinopathy. This study aimed to expand the mutational spectrum of dysferlinopathies, to further study one case with diagnostic ambiguity, and to identify the diagnostic value of dysferlin expression in total peripheral blood mononuclear cells (PBMC).Methods: The clinical and molecular profiles of dysferlinopathies in eight Chinese patients were evaluated. We also conducted magnetic resonance imaging (6/8) and determined dysferlin protein expression in muscle (7/8) and PBMC (3/8).Results: Nine of the 13 DYSF mutations identified were novel. One patient was homozygous for the Gln111Ter mutation by genomic DNA sequencing but was found to be heterozygous by sequencing of cDNA from total PBMC. A daughter of this patient did not carry any Gln111Ter mutation. Abnormal muscle MRI with predominant involvement of the medial gastrocnemius and soleus muscle was observed in 5/6 patients. Dysferlin levels were significantly reduced (immunohistochemistry/immunoblot) or absent (immunohistochemistry) in muscle and total PBMC (26–39%) for most patients. Sarcoplasmic accumulation of dysferlin was detected in one patient.Conclusion: Genomic DNA sequencing detects frequent homozygous mutations, while fewer heterozygous mutations in cDNA are detected after posttranscription. Total PBMC may serve as an alternative to confirm diagnosis and to guide further testing in dysferlinopathies. Our results contribute to the mutational spectrum of dysferlinopathies.