bluuebunny/crossref_metadata_2025_split huggingface dataset:
Qatar Biobank: COVID-19 biorepository project
Authors: Afifi Nahla , Fthenou Eleni , El Deeb Marwa , Frenneaux Michael , Al Thani Asma , Latif Al Khal Abdul 
Published: October 2021

Background: The rapid spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its resulting disease (COVID-19) is one of the greatest global public health crisis of the recent decades. The COVID-19 Biorepository is a national project aimed to support the high demand of biomedical research by multiple groups and the need to have access to high quality, curated clinical data, and specimens contributing to the understanding of, and response to, the COVID-19 pandemic and its impacts in Qatar. Methods/Case presentation: Patients with a laboratory diagnosis of COVID-19, who were Qatar residents that could communicate in Arabic, English, Hindi, and Urdu were eligible to participate in the study. COVID-19 diagnosed patients were recruited at the time of their disease period from the main three public hospitals (Communicable Disease Center, Cuban, and Hazm Mebaireek Hospitals) serving as isolation facilities of symptomatic patients in Qatar, during a 7-month period from March 2020 until September 2020. Consented participants were followed up on a weekly basis until recovery, and then monthly for a year. Sociodemographic and clinical data were collected in electronic questionnaires via a face-to-face interview by trained Qatar Biobank (QBB) staff. Results: A total of 2097 consented participants were recruited up to September 2020, males (N = 1050) and females (N = 1047), with a mean age of 41 years (SD: 15.5). 61.0% of the participants had at least one follow up while 27% adhered to monthly follow up visits. Data was collected for 99.7% of the participants, while the follow up process is still ongoing. In total there are 107,171 high quality specimens in the biorepository including plasma, erythrocytes, buffy coat, serum, PAXgene whole blood, nasopharyngeal secretions, and DNA. Conclusion: The COVID-19 Biorepository is a national asset to illuminate the pathophysiological and identify markers of disease prognosis as well as to describe the clinical features and epidemiology of COVID-19 in Qatar and worldwide.
Development of an in-house COVID-19 serology ELISA Test
Authors: Chowdhury Shazeda , Taleb Sara , Elgamal Mahmoud , Hassan Nesyia , Nomikos Michail , Hssain Ali Ait , Zughaier Susu M 
Published: October 2021

Background: COVID-19 pandemic created an unprecedented demand for reagents and diagnostic tools to confirm COVID-19 cases. Thus, the development of a robust in-house diagnostic test is considered of high importance. Within a few days after exposure, the human body produces specific antibodies that recognize the surface proteins of the invading SARS-CoV-2 virus. Therefore, virus specific immunoglobulins are neutralizing antibodies and their appearance in the blood is a good sign of immunity. The aim of this study was to develop an in-house COVID-19 serology ELISA test to quantify induced antibody responses. This test can help identify convalescent plasma donors with high antibody titers that can be used to treat other patients. Methods: Spike protein antigen is highly expressed in SARS-CoV-2. Recombinant protein corresponding to the spike receptor-binding domain (RBD), which binds to specific antibodies circulating in COVID-19 patients’ blood was used as the antigen in this colorimetric ELISA test. Briefly, a 96-microtiter well plate was coated with RBD protein, where serum dilutions were added. Antibody titers were detected using an anti-human IgG- peroxidase labelled antibody and the substrate o-phenylenediamine dihydrochloride; measured at optical density (OD) of 450 nm (). Results: The in-house quantitative serology test was validated using serum samples collected from severe COVID-19 patients (n = 282) admitted to the intensive care unit at Hamad General Hospital. Serum samples from non-COVID-19 (n = 10) were used as a negative control. We detected high antibody titers in ~90% of COVID-19 sera. In contrast, no SARS-CoV-2 specific antibodies were detected in the serum of non-infected subjects (n = 6), pooled human serum collected before 2019, or Middle East Respiratory Syndrome (MERS) infected subjects (n = 3) confirming the specificity and the sensitivity of this in-house serology test. Conclusion: This in-house quantitative serology test is sensitive, specific, and inexpensive. The test can address the rising issue of COVID-19 supply chain globally and foster the capacity-building efforts envisioned by Qatar University.
вast crops in russia and abroad: the state, problems and prospects of their processing
Authors: Новиков Э.В. , Басова Н.В. , Безбабченко А.В. 
Published: October 2021

Представлен анализ состояния, проблем и перспектив производства и переработки лубяных культур в России и зарубежных странах, используя многолетние собственные и другие исследования. Показано, что: с 2010 года площади посева лубяных культур в РФ увеличивались, но при этом, она, входя в тройку лидеров по производству льняных тканей, пока отстает от зарубежных стран по темпам роста первичной и глубокой переработки, по-прежнему остается проблема покупки нового технологического оборудования силами льнопенькозаводов. Основными производителями лубяных культур являются СНГ, Аргентина, Канада, США, Индия, Чехия, Германия, Франция, Бельгия, Голландия, Казахстан и другие. Определены в РФ: основные регионы возделывания лубяных культур; динамика роста цен на технологическое оборудование и волокно первичной переработки; состав и цены различных линий их первичной переработки; мировые производители льняных тканей. Сформулированы причины, тормозящие эффективность первичной и глубокой переработки лубяных культур в РФ.
The analysis of the state, problems and prospects of production and processing of bast crops in Russia and foreign countries is presented, using many years of own and other research. It is shown that: since 2010, the area of sowing of bast crops in the Russian Federation has increased, but at the same time, it is one of the three leaders in the production of linen fabrics, while it lags behind foreign countries in terms of growth rates of primary and deep processing, there is still a problem of buying new technological equipment by 31 flax mills. The main producers of bast crops are the CIS, Argentina, Canada, the USA, India, the Czech Republic, Germany, France, Belgium, the Netherlands, Kazakhstan and others. The following are defined in the Russian Federation: the main regions of cultivation of bast crops; the dynamics of price growth for technological equipment and fiber of primary processing; the composition and prices of various lines of their primary processing; world manufacturers of linen fabrics. The reasons hindering the effectiveness of primary and deep processing of bast crops in the Russian Federation are formulated.
Hardness and Conductivity of Die Forged ZYK530 Magnesium Alloy
Authors: CAO Fenghong , XU Yaohui , CHEN Chang , QIN Zhaohui , DENG Chi 
Published: October 2021

The relationship among the microstructure, hardness and electrical conductivity of the as-forged ZYK530 Mg alloy after heat treatment was analyzed and studied using a microscope, X-Ray Diffractometer, eddy current conductivity meter, and Vickers microhardness tester, to explore optimum heat treatment process of ZYK530 Mg alloy. The results show that: with the prolongation of holding time, the electrical conductivity and microhardness show the same change trend, both of which show an oscillatory upward trend, and then decrease in an oscillatory downward trend after reaching the peak value. There is a linear positive correlation between the conductivity and the hardness, and the fitting results of the conductivity and hardness are in good agreement with the measured results; combined with the actual production, when the heat-treatment is 480 ℃ × 8 h + 220 ℃ × 3 h, the highest hardness is 79.2 HV, the electroconductivity is 36.2%IACS, and the comprehensive performance is the best, which is the best heat treatment process.
Three new species of the subterranean genus Guiodytes from Guangxi, China (Coleoptera: Carabidae: Clivinini)
Authors: Huang Sunbin , Zhou Jiajun , Tian Mingyi , Faille Arnaud 
Published: October 2021

Three new species of the genus Guiodytes Tian, 2013 are described from the limestone caves of Guangxi Zhuang Autonomous Region, southern China: Guiodytes weii Huang & Faille sp. nov. and Guiodytes yueliangensis Huang & Tian sp. nov. from Dapo Dong and Huang Dong caves, respectively, in Huanjiang County, northernmost Guangxi; Guiodytes inexpectatus Tian & Zhou sp. nov. from the Zhuzhu Dong cave in Longzhou County, southwestern Guangxi. All of the six known species of Guiodytes are endemic to Guangxi, ranging from the southwest to the northernmost. A modified key to species and a distribution map for Guiodytes are provided.
The Modeling and Optimal Control of a Hybrid Propulsion System for an Ice-Capable Tanker
Authors: Zhou Yi , Pazouki Kayvan , Norman Rosemary 
Published: October 2021

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With the effects of global warming, the North Sea Route has become an economic option for cargo transportation because of the shorter distance between East Asia and Europe. Generally, conventional mechanical propulsion systems installed in ice-capable tankers suffer from significant drawbacks because of poor fuel efficiency when sailing at low speed, therefore, advanced technologies have been applied such as diesel electric and nuclear-powered propulsion; however, drawbacks still exist. Hybrid propulsion is a more environmental-friendly, economical solution for ships with icebreaking capability, which can address the drawbacks in both diesel electric and nuclear power systems. In this paper, modeling of system components is presented and implemented in MATLAB Simulink. A primary control strategy is applied to the system to ensure system stability, and an advanced secondary strategy is developed and applied to the power sources to minimize fuel consumption. Given two scenarios, the simulation results of the hybrid propulsion system developed in this research and those of diesel electric propulsion systems with DC and AC distribution systems are compared and indicate that the hybrid system can offer up to 22.4% fuel savings over ice-loading condition, and 39.5% fuel reduction over the particular voyage of varying speed in open water is applied in this paper.

Introduction
In recent years, some sea routes that were previously blocked by ice have become increasingly accessible in the warmest months of the year due to the effects of global warming. Researchers have estimated that, by 2030, the percentage of Arctic shipping will have increased to 25% of cargo trade between Europe and Asia (Lasserre 2019).
Northern Sea Route (NSR) shipping provides benefits for international trade, but challenges still exist. Increasing carbon emissions have seriously impacted the Arctic environment (Hassol & Corell 2006). Table 1 shows the total number of ships using Heavy Fuel Oil (HFO) in Arctic waters in 2015, and associated black carbon emissions, as published by the IMO (Comer et al. 2017). As it is shown, oil tankers made up just 4.5% of all ships entering Arctic waters but despite their low proportion, they were responsible for 17% of black carbon emissions. Thus, an environmentally friendly and fuel-efficient propulsion system to reduce these emissions from tankers trading in Arctic waters is required.
Fatores motivacionais para o trabalho em instituições de ensino superior
Authors: Azevedo Leonardo Ferreira de , Teixeira Maria Waldilene Sousa , Gomes Filho Antoniel dos Santos 
Published: October 2021

O estudo da motivação tornou-se importante para as organizações, pois os colaboradores motivados tendem a permanecerem por mais tempo na empresa, além de produzirem com mais eficiência, assim, impactando no clima organizacional que tende a melhorar constantemente. Diante disso, a presente pesquisa teve como objetivo geral identificar os fatores motivacionais apresentados por colaboradores de Instituições de Ensino Superior (IES) por meio de uma revisão da literatura. Para tanto, buscou-se descrever os fatores para satisfação dos colaboradores das instituições de ensino superior; verificar as estratégias criadas para motivação dos colaboradores nas Instituições; identificar as principais teorias da motivação que fundamentam as estratégias da gestão de pessoas para motivar os colaboradores. Sobre a esfera metodológica adotou-se uma pesquisa de natureza básica com objetivo exploratório, utilizando-se da abordagem qualitativa, configurando-se como revisão de literatura sistemática. Com relação aos resultados obtidos verificou-se as variáveis que motivam os colaboradores dentro das IES como a presença de treinamento e desenvolvimento na organização, comunicação mais eficiente, evitando possíveis ruídos e conflitos entre as pessoas, além da percepção positiva dos colaboradores referente ao reconhecimento recebido. Também é perceptível, as relações interpessoais satisfatórias nas instituições, promovendo um ambiente de trabalho mais agradável e proveitoso para os funcionários das IES. Assim, pode-se concluir que as variáveis apresentadas neste estudo contribuem para a satisfação dos colaboradores nas IES.
Análise do conhecimento de estudantes da educação básica sobre dengue
Authors: Marinho Willian Rodrigues da Costa , Egidio Jonatha Anderson Fraga 
Published: October 2021

A dengue é uma doença sistêmica causada por um vírus. A transmissão desta doença viral ocorre através de mosquitos do gênero Aedes. Atualmente o vírus da dengue passou a dispersar-se de forma eminente por países tropicais e subtropicais. Assim, a dengue vem configurando um quadro preocupante, uma vez que se tornou um problema de saúde pública em todo mundo. Atualmente busca-se controlar a doença e diminuir os riscos aos seres humanos, visto que não há cura até o momento. Neste sentido, as medidas socioeducativas apresentam um papel relevante no combate aos vetores da doença. O objetivo deste trabalho foi avaliar o conhecimento de estudantes do terceiro ano de escolas estaduais de Macaé sobre a dengue. Foram aplicados questionários aos alunos do terceiro ano das Escolas Estaduais Luiz Reid, Irene Meirelles e Matias Neto em Macaé. O questionário composto por 13 perguntas do tipo múltipla escolha, foi elaborado com base nas informações esperadas de um aluno de terceiro ano sobre o assunto. Após aplicação os questionários foram analisados e tabulados no programa de Excel® (Windows 2013) para confecção de gráficos e tabelas. Com base nos resultados, identificou-se que os estudantes sabem que o agente causador da dengue é um vírus (39%) e que a transmissão da doença se dá por meio do mosquito Aedes aegypti (54%). Os alunos ainda fazem confusão com relação aos problemas de saúde pública que contribuem para a expansão da dengue, (3%) deles não têm consciência que o lixo acumulado contribui para expansão da doença. Os sintomas da dengue ainda são desconhecidos por (19%) dos estudantes, talvez pelo desconhecimento dos termos médicos utilizados. O meio pelo qual os alunos ouvem falar sobre a dengue variou entre as escolas, sendo a televisão e a escola os meios mais citados. Os alunos reconhecem que a dengue pode ser prevenida e pode causar a morte, mas 18% responderam que já foi encontrado foco da doença em sua residência, apesar de dizerem que medidas de segurança são tomadas a fim de evitar a proliferação do mosquito em suas casas. Conclui-se que, a maioria dos alunos do terceiro ano das escolas estaduais de Macaé têm os conhecimentos básicos sobre a transmissão da dengue, porém o tema precisa ser melhor trabalhado em algumas escolas, bem como os estudantes precisam estar mais atentos às medidas de prevenção da disseminação da doença em suas casas.
Dynamics of a Reaction Diusion Brucellosis Model
Authors: Lolika Paride O. , Mushayabasa Steady 
Published: October 2021

To understand the effects of animal movement on transmission and control of brucellosis infection, a reaction diffusion partial differential equation (PDE) brucellosis model that incorporates wild and domesticated animals under homogeneous Neumann boundary conditions is proposed and analysed. We computed the reproductive number for the brucellosis model in the absence of spatial movement and we established that, the associated model has a globally asymptotically stable disease-free equilibrium whenever the reproductive number is less or equal to unity. However, if the reproductive number is greater than unity an endemic equilibrium point which is globally asymptotically stable exists. We performed sensitivity analysis on the key parameters that drive the disease dynamics in order to determine their relative importance to disease transmission and prevalence. For the model with spatial movement the disease threshold is studied by using the basic reproductive number. Additionally we investigate the existence of a Turing stability and travelling waves. Our results shows that incorporating diffusive spatial spread does not produce a Turing instability when the reproductive number R0ODE associated with the ODE model is less than unity. Finally the results suggest that minimizing interaction between buffalo and cattle population can be essential to manage brucellosis spillover between domesticated and wildlife animals. Numerical simulations are carried out to support analytical findings.
Evaluation of Dental Hygiene and Para-functional Habits in Oro-facial Pain among Patients Visiting Sharad Pawar Dental College & Hospital: A Questionnaire Based Cross Sectional Study
Authors: Tijare Raksha , Chhabra Kumar Gaurav , Reche Amit , Madhu Priyanka Paul , Agrawal Sakshi , Chandak Vaishnavi 
Published: October 2021

Background: It is important for dental care providers to make the correct diagnosis and treatment of the oro-facial region. For treatment planning, it is very crucial to eliminate the risk factors. In this study, we will evaluate dental hygiene and para-functional habits in oro-facial pain among patients visiting Sharad Pawar Dental College and Hospital.
Objectives: To assess the prevalence of oro-facial pain associated with oral hygiene practices and para-functional habits among patients visiting Sharad Pawar Dental College and Hospital. Also, explore the co-relation of dental hygiene, para-functional habits, and oro-facial pain.
Methodology: Patients from Sharad Pawar Dental College and Hospital are sorted for study. The current study will randomly recruit male and female participants of Sharad Pawar Dental College and Hospital encountered with oro-facial pain and unfamiliar oro-facial pain contributors. That will be sorted out via the convenient sampling method. Procedures in the contemporary study will be overseen in full accordance with the Public Health Department at SPDC and former the wince data collection, each contributor will be required to sign a written informed consent. Three interviewers will interview the contributors using a validated questionnaire at SPDC.
Expected Results: The expected result of this study will evaluate dental hygiene and para-functional habits of oro-facial pain among patients visiting Sharad Pawar Dental College and Hospital. In this study, we will evaluate the co-relation of dental hygiene, para-functional habits, and orofacial pain to find any significant association between these three factors.
Conclusion: This study will be conducted to assess the prevalence of orofacial pain associated with oral hygiene practices and para-functional habits among patients visiting Sharad Pawar Dental College and Hospital. Also we will evaluate the co-relation of dental hygiene, para-functional habits, and orofacial pain to find any significant association between these three factors.
Antibacterial, Antifungal Chalcone Derivatives as EGFR Inhibitors-Molecular Docking and ADMET Studies
Authors: Sattu Hemalatha , Nerella Indira rani , Tangeda Saritha Jyostna 
Published: October 2021

Aim: In our earlier research, we have synthesized series of substituted 1-(2, 5-dimethyl thiophene-3yl)-(4-substituted phenyl)-2-propene-1-one derivatives and evaluated them for their anti-bacterial and antifungal activity. In recent years, chalcone derivatives are proved for their varied pharmacological effects ranging from antimicrobial activity to anti-cancer effects. In this study, we have hypothesized the efficiency of our earlier synthesized anti-bacterial and antifungal chalcone derivatives for their potential inhibition of epidermal growth factor receptor protein (EGFR), through molecular docking studies.
Methodology: Molecular docking simulation studies are performed using the Glide XP module of Schrodinger Suite and ligand binding energies are also calculated.
Results: Molecular docking studies of the selected compounds against EGFR revealed docking scores ranging from -6.746 (compound 5) to -5.681 (compound 3) and also provided insight into binding conformations of the ligands in the EGFR protein environment. Additionally, molecular property and Absorption, Distribution, Metabolism, and Excretion (ADME) predictor analysis is also performed for the dataset ligands, which further provided the probable explanation for the binding potentials.
Conclusion: Among all the tested dataset ligands, compound 5 has shown the highest dock score (-6.746) with better ADME profiles. Binding energies in the protein-ligand interactions explain how fit the ligand binds with the target protein. Molecular docking studies of these anti-bacterial, antifungal chalcone derivatives provided deeper insights in understanding the probable conformations of these tested ligands in the EGFR protein environment.
Left Ventricular Hypertrophy (LVH) in Patients with Advanced Stages of Chronic Kidney Disease (CKD)
Authors: Khan Faiza Nafees , Begum Imtiaz , Raza Syed Ali , Hussain Sohail , Sidhwani Santosh Kumar , Wasti Hina 
Published: October 2021

Objective: To determine the left ventricular hypertrophy (LVH) prevalence in patients admitted with advanced stage of Chronic kidney disease at Ziauddin hospital.
Methodology: This was a cross-sectional study conducted in department of Nephrology of Ziauddin University Hospital, Karachi from January to July 2016. The inclusion criteria involved patients with CKD stages 3-5 undergoing two-dimensional M mode Doppler echocardiography. The sample size of the study was 147. LVH was considered as positive when Inter-ventricular-septal-wall-thickness in diastole (IVSd) >11 mm, Left-Ventricular-Septal-Wall-Thickness in diastole (LVPWd) >11 mm and Left-Ventricular-Mass-Index (LVMi) >131 g/m2 for men and > 100 g/m2 for women. The exclusion criteria included patients with terminal illness, on mechanical ventilator support, valvular heart diseases and congenital heart diseases, liver diseases and patients with acute kidney injury on chronic kidney disease.
Results: 88 male and 59 female patients were included. The mean duration of CKD was 7.02±1.60 years. 94(63.9%) study subjects were observed with left ventricular hypertrophy. A significant association of LVH was observed with gender and CKD Stages.
Conclusion: LVH can be easily diagnosed and assessed by M-mode or 2D echocardiography. The prevalence was high (60.5%) in stage 3–5 CKD patients.