bluuebunny/crossref_metadata_2025_split huggingface dataset:
Candidate Regulatory Sequence Elements for Cell Cycle-Dependent Transcription in Saccharomyces cerevisiae
Authors: Wolfsberg Tyra G. , Gabrielian Andrei E. , Campbell Michael J. , Cho Raymond J. , Spouge John L. , Landsman David 
Published: November 2021

Recent developments in genome-wide transcript monitoring have led to a rapid accumulation of data from gene expression studies. Such projects highlight the need for methods to predict the molecular basis of transcriptional coregulation. A microarray project identified the 420 yeast transcripts whose synthesis displays cell cycle-dependent periodicity. We present here a statistical technique we developed to identify the sequence elements that may be responsible for this cell cycle regulation. Because most gene regulatory sites contain a short string of highly conserved nucleotides, any such strings that are involved in gene regulation will occur frequently in the upstream regions of the genes that they regulate, and rarely in the upstream regions of other genes. Our strategy therefore utilizes statistical procedures to identify short oligomers, five or six nucleotides in length, that are over-represented in upstream regions of genes whose expression peaks at the same phase of the cell cycle. We report, with a high level of confidence, that 9 hexamers and 12 pentamers are over-represented in the upstream regions of genes whose expression peaks at the early G1, late G1, S, G2, or M phase of the cell cycle. Some of these sequence elements show a preference for a particular orientation, and others, through a separate statistical test, for a particular position upstream of the ATG start codon. The finding that the majority of the statistically significant sequence elements are located in late G1 upstream regions correlates with other experiments that identified the late G1/early S boundary as a vital cell cycle control point. Our results highlight the importance of MCB, an element implicated previously in late G1/early S gene regulation, as most of the late G1 oligomers contain the MCB sequence or variations thereof. It is striking that most MCB-like sequences localize to a specific region upstream of the ATG start codon. Additional sequences that we have identified may be important for regulation at other phases of the cell cycle.[A companion website to this manuscript is available fromhttp://www.ncbi.nlm.nih.gov/CBBresearch/Landsman/Cell_cycle_data]
Impacts of COVID-19 on patterns of meat and seafood consumption: evidence from Australia
Authors: Rolfe John , Rajapaksa Darshana , De Valck Jeremy , Star Megan 
Published: November 2021

PurposeIn 2020, mechanisms to limit the chain of transmission of coronavirus disease 2019 (COVID-19) in Australia led to widespread restrictions on population mobility and business operations. Such conditions provide a natural experiment that may help to provide insights into consumer behaviour and future trends in food consumption. The overall objective of this study is to explore the possible impacts of COVID-19 on meat consumption patterns in Australia, both in the short and medium term, and to explore whether there have been impacts on the underlying drivers for consumption.Design/methodology/approachThe research reported in this paper analyses the impacts of COVID-19 on meat and seafood consumption in Australia, drawing on a national random survey of 1,200 participants in June 2020. Survey data on past and current consumption rates are compared to respondent estimates of their future consumption behaviour, and ordered probit models are used to identify whether consumption changes can be explained by socio-demographic, attitudinal or economic factors.FindingsTwo potential scenarios were evaluated to explore future consumption trends. The first “acceleration” scenario is that the restrictions would encourage people to speed up existing declines in meat consumption, perhaps taking more account of credence factors such as health, animal welfare and environmental issues. The second “transformation” scenario is that people will change consumption patterns, perhaps moving more towards home-cooked meals and increased consumption. Slightly stronger support was found for the transformation scenario, indicating that consumption rates for most meats and seafood will be stable or increase over the next five years.Originality/valueThis study capitalises on changed social and economic settings generated by COVID-19 to test the effects on consumption of meat (chicken, beef, pork, lamb) and seafood at a national level. Ordered probit models are applied to evaluate participant data on their future intentions for meat consumption to test two scenarios, finding stronger support for the “transformative” scenario than the “accelerate” scenario.
International mobile marketing: a satisfactory concept for companies and users in times of pandemic
Authors: Florido-Benítez Lázaro 
Published: November 2021

PurposeThis study’s purpose is to analyze the international mobile marketing (IMK) in order to stage the importance of this tool in the internationalization of companies. Our understanding of mobile marketing is constantly evolving, due to its high business penetration in a world globalized by technologies.Design/methodology/approachA review of the relevant literature on IMK, companies and customers is undertaken to understand the link between them. The paper begins by explaining the coronavirus disease 2019 is accelerating the change of the rules of the game in traditional and online commerce around the world. Furthermore, this study uses secondary data from organisation for economic co-operation and development (OECD), Sensor Tower, mobile marketing association (MMA), App Annie, among others, to support research results.FindingsThe results have shown that IMK has opened a melting pot of opportunities for companies and consumers in this period of pandemic; the potential of this tool is being redefined, in order to identify, anticipate and satisfy customers requirement profitably and efficiently. This study aims to provide an assessment of new concept of IMK and how this tool has to be integrated into the firm’s digital marketing strategies.Originality/valueThe study contributes to make better future decisions in the international digital expansion of companies by company executives and marketing experts. This paper provides a comprehensive framework intended to guide research efforts focusing on digital marketing as well as to aid practitioners in their quest to achieve IMK success.
Determining response time factors of emergency medical services during the COVID-19 pandemic
Authors: Mulyono Nur Budi , Pambudi Noorhan Firdaus , Ahmad Lukni Burhanuddin , Adhiutama Akbar 
Published: November 2021

Purpose
The lack of studies about the response time of emergency medical service during the coronavirus disease 2019 (COVID-19) pandemic in a dense city of a developing country has triggered this study to explore the factors contributing to a high response time of ambulance service to reach patients in need. An evaluation of contributing factors to the response time is necessary to guide decision-makers in keeping a high service level of emergency medical service.

Design/methodology/approach
This research employed an agent-based modeling approach with input parameters from interviews with emergency medical service staff in Bandung city, Indonesia. The agent-based model is established to evaluate the relevant contribution of the factors to response time reduction using several scenarios.

Findings
According to agent-based simulation, four factors contribute to the response time: the process of preparing crew and ambulance during the pandemic, coverage area, traffic density and crew responsiveness. Among these factors, the preparation process during the pandemic and coverage area significantly contributed to the response time, while the traffic density and crew responsiveness were less significant. The preparation process is closely related to the safety procedure in handling patients during the COVID-19 pandemic and normal time. The recommended coverage area for maintaining a low response time is 5 km, equivalent to six local subdistricts.

Research limitations/implications
This study has explored the factors contributing to emergency medical response time. The insignificant contribution of the traffic density showed that citizens, in general, have high awareness and compliance to traffic priority regulation, so crew responsiveness in handling ambulances is an irrelevant factor. This study might have different contributing factors for less dense population areas and focuses on public emergency medical services provided by the local government.

Practical implications
The local government must provide additional funding to cover additional investment for ambulance, crew and administration for the new emergency service deployment point. Exercising an efficient process in ambulance and crew preparation is mandatory for each emergency deployment point.

Originality/value
This study evaluates the contributing factors of emergency medical response time in the pandemic and normal situation by qualitative analysis and agent-based simulation. The performance comparison in terms of medical response time before and after COVID-19 through agent-based simulation is valuable for decision-makers to reduce the impact of COVID-19.
An IoT-based agriculture maintenance using pervasive computing with machine learning technique
Authors: Kailasam Swathi , Achanta Sampath Dakshina Murthy , Rama Koteswara Rao P. , Vatambeti Ramesh , Kayam Saikumar 
Published: November 2021

PurposeIn cultivation, early harvest offers farmers an opportunity to increase production while decreasing the chances of lower crop production rates, ensuring that the economy remains balanced. The significant reason is to predict the disease in plants and distinguish the type of syndrome with the help of segmentation and random forest optimization classification. In this investigation, the accurate prior phase of crop imagery has been collected from different datasets like cropscience, yesmodes and nelsonwisc . In the current study, the real-time earlier state of crop images has been gathered from numerous data sources similar to crop_science, yes_modes, nelson_wisc dataset.Design/methodology/approachIn this research work, random forest machine learning-based persuasive plants healthcare computing is provided. If proper ecological care is not applied to early harvesting, it can cause diseases in plants, decrease the cropping rate and less production. Until now different methods have been developed for crop analysis at an earlier stage, but it is necessary to implement methods to advanced techniques. So, the detection of plant diseases with the help of threshold segmentation and random forest classification has been involved in this investigation. This implemented design is verified on Python 3.7.8 software for simulation analysis.FindingsIn this work, different methods are developed for crops at an earlier stage, but more methods are needed to implement methods with prior stage crop harvesting. Because of this, a disease-finding system has been implemented. The methodologies like “Threshold segmentation” and RFO classifier lends 97.8% identification precision with 99.3% real optimistic rate, and 59.823 peak signal-to-noise (PSNR), 0.99894 structure similarity index (SSIM), 0.00812 machine squared error (MSE) values are attained.Originality/valueThe implemented machine learning design is outperformance methodology, and they are proving good application detection rate.
Disruptions in sourcing and distribution practices of supply chains due to COVID-19 pandemic: a sustainability paradigm
Authors: Sharma Vishal , Singh Amrinder , Rai Siddharth Shankar 
Published: November 2021

Purpose
The present research paper is an attempt to study how COVID-19 can affect the global sourcing practices of various supply chain intermediaries across the demand chain. This study aims to explore and is an attempt to understand the overall impact of COVID-19 on the sustainable operations of the firm such as sourcing, procurement, economic performance, social responsibility, consumption and distributions.

Design/methodology/approach
This study uses a quantitative technique using data collected from 708 respondents. Structural equation modeling (SEM) has been applied to test the proposed model and hypothesis.

Findings
The findings of the study suggest that sourcing practices, distribution and sustainability considerations of manufacturers, suppliers, distributors and retailers are affected by COVID-19 to a great extent but the pandemic has also led to making supply chain intermediaries understand the changing dynamics of the business scenario which can help them in their own strategic and business evolution.

Research limitations/implications
The current disruptions throughout global delivery chains caused by COVID-19 affect badly, the already poor-performing supply chains. Hence, the present study provides fresh insight on how organizations can limit the ill effects of COVID-19 by safeguarding some of their key sustainable operations in a post-pandemic business scenario.

Originality/value
The present study takes into consideration how core supply functions such as sourcing, distribution and manufacturing and various sustainable operations are disrupted by pandemic and its after-effects. This knowledge base can help business organizations to mitigate such problems/disruptions in the future.
The impact of mental health information overload on community education programs to enhance mental health-care seeking
Authors: Bink Andrea B. , Corrigan Patrick 
Published: November 2021

Purpose
Education programs seek to increase the public’s mental health literacy so they are better able to, among other things, help others engage in care when in need. This task may be diminished when such programs overwhelm participants with too much information. In addition, participants might arrive to the program with information overload related to the covered health topic. Information overload about health topics has been shown to influence attitudes and behavioral intentions. The overall purpose of the current study was to examine the relationship between mental health information overload, topic interest, and care seeking recommendations.

Design/methodology/approach
The current study tested a path suggesting high mental health information overload diminishes interest in learning about mental health, which in turn reduces recommendations to others to seek appropriate help when in need. Participants completed online measures of mental health information overload, topic interest and recommendations for care seeking. The data set analyzed represents valid responses from 221 participants. Structural equation modeling was completed to confirm the path model hypothesized for this study.

Findings
Structural equation modeling showed satisfactory fit and significant betas for the hypothesized path.

Originality/value
This study adds to the emerging literature on the impact of health information overload and is the first to the best of the authors’ knowledge to measure mental health information overload. Program developers should consider information overload in the ongoing development of public mental health education programs.
Personal goals in consumers' adoption of mHealth services
Authors: Schuster Lisa , Parkinson Joy 
Published: November 2021

PurposemHealth services are effective and cost efficient, yet wide-scale adoption of these services by consumers has yet to be achieved, constraining their public health benefit. Further investigation of non-technological determinants of mHealth adoption is needed; specifically, the role of consumers' goals has received scant attention and forms the research focus.Design/methodology/approachStudy 1 comprised 20 interviews with participants who possess a health goal, with the data analysed using an abductive reasoning approach. Study 2 was a 15-min online survey (n = 653), with the data analysed using multi-group structural equation modelling.FindingsStudy 1 identified several antecedents to the desirability and feasibility of consumers' health goals, which influence their desire to use mHealth services. Study 2 shows significant differences in the determinants of mHealth service acceptance depending on whether consumers set concrete as opposed to abstract goals, but social acceptance of mHealth services of these services is important for both groups.Practical implicationsThe findings suggest emphasising the importance of health goals to achieving other consumer goals (e.g. work or travel goals), the efficacy of mHealth services relative to other service alternatives for achieving those health goals, and the social acceptance of mHealth services to increase their uptake.Originality/valueThis study is the first to use construal-level theory to improve understanding of the role of consumers' goals in the adoption of mHealth services. By identifying the antecedents to goal desirability and feasibility, it also broadens the model of goal-directed behaviour.
The profile of the Portuguese regarding the perception of financial literacy
Authors: Santos Eulália Maria Mota , Tavares Vasco Capela , Ratten Vanessa , Tavares Fernando Oliveira 
Published: November 2021

PurposeThe purpose of this study is to identify the profile of the Portuguese regarding the perception of financial literacy.Design/methodology/approachThe utilized methodology is based on a questionnaire survey that assesses the perception of financial literacy. The sample is composed of 830 Portuguese individuals over 18 years old.FindingsThe results show that the financial literacy scale presents a tri-factor structure with adequate validity and reliability levels. The three obtained factors are designated 1-2-year financial planning and goals, long-term saving and taste for numeric calculations.Originality/valueThe originality in this study is shown in the application of the cluster analysis, which demonstrates the formation of three clusters that present different perceptions of financial literacy, classifying the Portuguese into a cluster of high financial literacy and taste for numeric calculation, a cluster of low financial literacy and a cluster of financial planning and saving but without the taste for numeric calculation.
Evaluation of thermal and physical properties of PMMA/PMVEMA-ES blends as organic coating
Authors: Hisham Shameer , Tajuddin Hairul Anuar , Muhamad Sarih Norazilawati , Zakaria Nur Zarith Diana Diana , Zainal Abidin Zul Hazrin , Abdul Halim Norhana 
Published: November 2021

Purpose
In this work, the blends of poly(methyl methacrylate), PMMA and poly(methyl vinyl ether-alt-maleic acid monoethyl ester), PMVEMA-ES are studied as organic coatings to evaluate the impact of intermolecular hydrogen bonding on the physical and thermal characteristics of the prepared coatings.

Design/methodology/approach
PMMA (Mw = 120,000 g mol-1) was chosen as our binder material. Due to the low adhesion property of PMMA on polar substrates, it was blended with PMVEMA-ES, which contains polar –COOH groups, to improve the adhesion and thermal properties of the coatings by forming intermolecular hydrogen bonds. A cross-hatch adhesion test was carried out to evaluate the adhesion strength of different ratios of PMMA/PMVEMA-ES blends as coatings. In addition, changes in the glass-transition temperature, Tg as the composition varies were studied using Differential Scanning Calorimetry, DSC. Then, glossiness and hiding power tests were also conducted to evaluate the physical properties of the prepared coatings.

Findings
Upon a closer look at the DSC results, it was found that blends consisting of 12.5, 25.0 and 87.5 wt. % PMMA were completely compatible due to the presence of only a single Tg in their thermograms. Other blend compositions showed two distinct Tgs, indicating partial compatibility. Furthermore, the addition of PMVEMA-ES caused the Tg of PMMA to shift to lower temperatures, a strong indication of intermolecular hydrogen bonding interactions between the two components. From the cross-hatch adhesion results, the addition of PMVEMA-ES improved the adhesion properties of PMMA coating, except for blends consisting of 62.5 and 75.0 wt. % PMMA possibly due to the partial incompatibility between the two components. These findings were further corroborated with the results of glossiness and hiding power measurements. The superior result was seen for the blend consisting of 12.5 wt. % PMMA with strong adhesion property, high glossiness, compatibility and high translucency.

Practical implications
PMVEMA-ES can potentially be used as an adhesion promoter in PMMA-based coating formulations.

Originality/value
This is the first report on the properties of PMMA/PMVEMA-ES blends as coatings.
Parents’ literacy on mobile advertising aimed at children: a cross - cultural approach
Authors: Robayo-Pinzon Oscar , Rojas-Berrio Sandra , Núñez-Gómez Patricia , Miguélez-Juan Blanca , García-Béjar Ligia 
Published: November 2021

Purpose
The use of mobile devices by children and adolescents is increasing significantly; therefore, it is relevant to research the level of advertising literacy (AL) of parents who act as mediators between children and mobile advertising. This study aims to explore the conceptual, moral and attitudinal dimensions of AL and its relationship with different styles of parental control.

Design/methodology/approach
A cross-sectional survey was applied simultaneously to a sample of parents with children between 5 and 16 years old in three Spanish-speaking countries: Mexico, Spain and Colombia. Participants from the three countries were recruited via online social media networks and were asked to fill in an online survey. A questionnaire, which has been adapted from previous literature to suit the mobile advertising context and the population of interest, was designed. Cross-country samples of varying sizes, with a predetermined quota of 200 participants for each country, were used. The total sample consisted of 1,454 participants.

Findings
Four factors of mobile AL were found, which, to a greater extent, correspond to the dimensions of AL proposed in the literature. The following are the dimensions that were identified: cognitive, moral, attitudinal and an emerging factor is known as “children’s perceived mobile AL.” Differences in parents’ perceived knowledge of mobile advertising, parental control styles and AL levels in the three countries were identified. Parents with an authoritative style were identified to have more knowledge than those with an indulgent style. Differences were also identified between countries concerning the amount of exposure that children have to mobile advertising, while no significant differences were found in the moral dimension.

Practical implications
Marketing practitioners and public policymakers must consider that parents differ in some dimensions of AL. Parents also seem to lack adequate knowledge about the advertising tools available to announcers that affect children and adolescents in a mobile communication environment. Therefore, government agencies should consider developing mobile digital media literacy programs for parents.

Originality/value
This paper explores the dimensions of AL applied to the mobile context and identifies the level of parental mobile AL in three Spanish-speaking countries, as well as the differences between these sub-samples concerning parental mobile AL profiles and parental control styles, thus expanding the literature on AL with a cross-cultural approach.