bluuebunny/crossref_metadata_2025_split huggingface dataset:
SISTEM PENUNJANG KEPUTUSAN PENENTUAN JENIS TANAMAN HIAS DI TAMAN KOTA
Authors: Hernando Luki , Mardiansyah Yopy 
Published: April 2021

Abstract: Currently in almost every city around the world that loves flowers, including ornamental plants,. All cities are aggressively arranging their landscaping to compensate for motorized vehicle pollution or the arrangement of city parks planted with decorative gardens with the aim of greening the city. Sometimes there are problems in making decisions to determine suitable and good ornamental plants for planting in the city, in a decision that takes a long time. Determination of the types of ornamental plants to be planted through several factors such as leaf shape, color, stems and branches, roots and soil. On these issues, the authors conducted research on the determination of ornamental plants for city parks in the form of a decision support system application using the Analytical Hoerarchy Process (AHP) method. Keywords: analytical hoerarchy process (AHP); decisionnsupporttsystem (SPK), Abstrak: Saat ini hampirrdi setiap kota di seluruh dunia yang menyukai bunga termasuk tanaman hias, Semua kota gencar menata pertamanannya untuk mengimbangi polusi kendaraan bermotor maupun untuk penataan taman kota yang ditanami tamanan hias bertujuan untuk menghijaukan kota. Terkadang terdapat masalah dalam pengambilan keputusan untuk menentukan tanaman hias yang cocok dan bagus umtuk ditanam pad ataman kota, dalam pengambilan keputusan yang dilakukan terkadang memakan waktu yang cukup lama . Penentuan jenis tanaman hias yang akan ditanam melalui beberapa faktor seperti bentuk daun, warna, batang dan cabang, akar dan Tanah. Atas permasalahan tersebut penulis melakukan penelitian tentang penentuan tanaman hias untuk taman kota yang berupa aplikasi sistem pendukug keputusan yang menggunakan metode Analytical Hoerarchy Process (AHP). Kata kunci: proses analisis hirarkie (AHP); sistem pendukung keputusan (SPK)
‘The wish to paint’: Bowen and the Visual Arts
Authors: Waldron Michael 
Published: April 2021

Throughout her life, Elizabeth Bowen maintained a rich network of artist friends and acquaintances. She often attended exhibitions and was an astute, sometimes caustic critic in letters as well as reviews. Her short tenure as an art student is an often mentioned but rarely, if ever, explored biographical fact, yet it was a key moment in her creative development. It is perhaps unsurprising then that she began to write while ‘still under the influence of … the wish to paint.’ This essay considers Bowen's significant relationship with the visual arts, from her art training and networks to her critical engagement and deeply visual prose. In childhood, Bowen was taught to paint by Elizabeth Yeats and forged a lasting friendship with Mainie Jellett, one of Ireland's great modernists. In 1918, Bowen enrolled at the LCC Central School of Arts and Crafts but, convinced she lacked the requisite artistic talent, she withdrew from her studies after only two terms. This sense of failure plunged her into an artistic crisis from which writing offered a creative way forward. Tellingly, Bowen later reflected that her earliest stories ‘had the character of a last hope’. In describing the best of her writing as ‘verbal painting’, Bowen offers us a lens through which to conceptualise the dynamic dialogue between her more experimental prose and visual modernism. Drawing together aspects of her artistic formation, milieu, and taste, this essay ultimately seeks to provide a series of layered contexts to enrich our understanding of Bowen's fictions, including The Last September (1929) and To the North (1932).
Dynamic Changes in Microbiome Composition Following Mare’s Milk Intake for Prevention of Collateral Antibiotic Effect
Authors: Kushugulova Almagul , Löber Ulrike , Akpanova Saniya , Rysbekov Kairat , Kozhakhmetov Samat , Khassenbekova Zhanagul , Essex Morgan , Nurgozhina Ayaulym , Nurgaziyev Madiyar , Babenko Dmitriy , Markó Lajos , Forslund Sofia K. 
Published: April 2021

IntroductionProbiotics and prebiotics are widely used for recovery of the human gut microbiome after antibiotic treatment. High antibiotic usage is especially common in children with developing microbiome. We hypothesized that dry Mare’s milk, which is rich in biologically active substances without containing live bacteria, could be used as a prebiotic in promoting microbial diversity following antibiotic treatment in children. The present pilot study aims to determine the impacts of dry Mare’s milk on the diversity of gut bacterial communities when administered during antibiotic treatment and throughout the subsequent recovery phase.MethodsSix children aged 4 to 5 years and diagnosed with bilateral bronchopneumonia were prescribed cephalosporin antibiotics. During the 60 days of the study, three children consumed dry Mare’s milk whereas the other three did not. Fecal samples were collected daily during antibiotic therapy and every 5 days after antibiotic therapy. Total DNA was isolated and taxonomic composition of gut microbiota was analyzed by 16S rRNA amplicon sequencing. To assess the immune status of the gut, stool samples were analyzed by bead-based multiplex assays.ResultsMare’s milk treatment seems to prevent the bloom of Mollicutes, while preventing the loss of Coriobacteriales. Immunological analysis of the stool reveals an effect of Mare’s milk on local immune parameters under the present conditions.
Plasma Oxylipins: A Potential Risk Assessment Tool in Atherosclerotic Coronary Artery Disease
Authors: Le D. Elizabeth , García-Jaramillo Manuel , Bobe Gerd , Alcazar Magana Armando , Vaswani Ashish , Minnier Jessica , Jump Donald B. , Rinkevich Diana , Alkayed Nabil J. , Maier Claudia S. , Kaul Sanjiv 
Published: April 2021

Background: While oxylipins have been linked to coronary artery disease (CAD), little is known about their diagnostic and prognostic potential.Objective: We tested whether plasma concentration of specific oxylipins may discriminate among number of diseased coronary arteries and predict median 5-year outcomes in symptomatic adults.Methods: Using a combination of high-performance liquid chromatography (HPLC) and quantitative tandem mass spectrometry, we conducted a targeted analysis of 39 oxylipins in plasma samples of 23 asymptomatic adults with low CAD risk and 74 symptomatic adults (≥70% stenosis), aged 38–87 from the Greater Portland, Oregon area. Concentrations of 22 oxylipins were above the lower limit of quantification in &gt;98% of adults and were compared, individually and in groups based on precursors and biosynthetic pathways, in symptomatic adults to number of diseased coronary arteries [(1) n = 31; (2) n = 23; (3) n = 20], and outcomes during a median 5-year follow-up (no surgery: n = 7; coronary stent placement: n = 24; coronary artery bypass graft surgery: n = 26; death: n = 7).Results: Plasma levels of six quantified oxylipins decreased with the number of diseased arteries; a panel of five oxylipins diagnosed three diseased arteries with 100% sensitivity and 70% specificity. Concentrations of five oxylipins were lower and one oxylipin was higher with survival; a panel of two oxylipins predicted survival during follow-up with 86% sensitivity and 91% specificity.Conclusions: Quantification of plasma oxylipins may assist in CAD diagnosis and prognosis in combination with standard risk assessment tools.
Effects of Harvest and Fertilization Frequency on Protein Yield and Extractability From Flood-Tolerant Perennial Grasses Cultivated on a fen Peatland
Authors: Nielsen Claudia Kalla , Stødkilde Lene , Jørgensen Uffe , Lærke Poul Erik 
Published: April 2021

Paludiculture, and in particular the cultivation of perennial grasses as biomass feedstock for green biorefineries, may be an economic and environmentally sustainable option for agricultural peatlands in temperate regions. However, the optimal biomass quality for protein extraction from flood-tolerant grasses is largely unknown. The aim of this study was to define the combined effect of harvest and fertilization frequency, with one to five annual cuts, on protein yield and extractability for the grasses tall fescue (TF) and reed canary grass (RCG), cultivated on an agricultural fen peatland in Denmark.The content of protein fractions was determined according to the Cornell Net Carbohydrate and Protein System (CNCPS). We assessed protein extractability by lab-scale biorefinery techniques using a screw-press followed by acid precipitation of true protein. The two methods were compared to correlate potential extractable protein yields with actual biorefinery outputs. We found the highest annual biomass and crude protein (CP) yields in the two cut treatments, with 13.4 and 15.6 t dry matter (DM) ha−1 year−1, containing 2.9–3.4 t CP ha−1 year−1for TF and RCG, respectively. The highest neutral-extractable (fractions B1and B2) true protein yields of 1.1 and 1.5 t ha−1 year−1were found in the two cut treatments, representing 39% (TF) - 45% (RCG) of total CP. Using biorefining techniques, we were able to precipitate up to 2.2 t DM ha−1 year−1of protein concentrate, containing up to 39% CP. Significant correlations between methods were found, with a distinct relationship between CNCPS fractions B1+ B2and CP yield of the protein concentrate, indicating the suitability of the CNCPS as an indicator for extractable protein yields. Biomass and CP yields were not significantly improved beyond two annual cuts. However, timing and harvest frequencies significantly affected plant maturity and consequently extractable CP contents and protein concentrate yields. We conclude that TF and RCG are promising feedstocks for green biorefineries due to high biomass, extractable CP, and protein concentrate yields, and highlight the potential of flood-tolerant grasses, cultivated on wet agricultural peatlands, for an enhanced valorisation beyond the common utilisation for bioenergy.
Real-World Methotrexate Dose on Clinical Effectiveness and Structural Damage of Certolizumab Pegol With Rheumatoid Arthritis
Authors: Nozaki Yuji , Hidaka Toshihiko , Ri Jinhai , Itami Tetsu , Tomita Daisuke , Okada Akinori , Ashida Chisato , Ikeda Fusayo , Yamamoto Atsuhiro , Funahashi Keiko , Kinoshita Koji , Matsubara Tsukasa , Funauchi Masanori , Matsumura Itaru 
Published: April 2021

Objective: Rheumatoid arthritis (RA) treatments have markedly advanced with the introduction of biological agents, e. g., tumor necrosis factor (TNF) inhibitors. TNF inhibitors are demonstrated to be quite effective in combination with methotrexate (MTX), and sufficient doses of both agents are important to control RA's disease activity. However, not all RA patients can be treated with high-dose MTX due to contraindications related to the antimetabolite action of MTX or to tolerability concerns. In daily practice, this has resulted in reduced effectiveness of TNF inhibitors. We sought to determine whether the concomitant use of dose of MTX affected the clinical effectiveness, retention rate, and side effects of certolizumab pegol (CZP) for treating RA in a real-world setting. CZP is a pegylated–conjugated Fab' fragment of a humanized anti-TNF antibody that has high affinity to TNF.Patients and Methods: We divided Japanese RA patients treated with CZP (n = 95, 25–83 years old) into groups based on those with (n = 65) and without (n = 30) concomitant MTX and those treated with a high dose (≥8 mg, n = 41) or low dose (1– &lt;8 mg, n = 24) of MTX. We retrospectively analyzed the concomitant MTX doses' effects and side effects and the patient retention rate.Results: There were no significant differences among the CZP groups with and without MTX or the groups receiving the high vs. low MTX doses in the retention rate, the low disease activity rate, or the inhibitory effect in radiographic joint damage.Conclusion: CZP has the potential to be a useful biological agent to control RA's disease activity and the bone destruction in patients who cannot tolerate a sufficient MTX dose.
Methodological Quality Assessment of Budget Impact Analyses for Orphan Drugs: A Systematic Review
Authors: Abdallah Khadidja , Huys Isabelle , Claes Kathleen , Simoens Steven 
Published: April 2021

Objectives: This research aims to evaluate the methodological quality of budget impact analyses for orphan drugs and to provide suggestions for future analyses.Methods: Conference abstracts and peer-reviewed literature on budget impact analyses were collected through searches of Pubmed and Embase. ISPOR good practice guidelines were used as a methodological standard for budget impact analyses. Examined parameters encompassed: perspective, target population, data sources, intervention and comparator(s), time horizon, scope of costs, discounting, validation, assumptions and sensitivity analysis.Results: Seventy studies on individual orphan drugs and 21 studies on a combination of orphan drugs analyzing budget impact were identified. Overall, analyses considered a third-party payer perspective, reported periodic budget impacts over a one-to-five-year time horizon, and did not apply discounting. A dynamically fluctuating population and costs beyond drug costs were accounted for in 18.7% and 51.7% of studies, respectively. Input data were retrieved from published literature, clinical trials, registries, claims databases, expert opinions, historical data and market research. Assumptions were mostly made about population size and intervention/comparator(s) market uptake, but these assumptions were rarely justified and their impact was insufficiently explored through sensitivity analyses. Budget impact results were rarely validated.Conclusion: Existing budget impact analyses for orphan drugs are concise, vary greatly and are of substandard methodological quality. To eliminate possible bias in future budget impact analyses, future studies should adhere to national or ISPOR good practice guidelines on budget impact analysis.
Feasibility of Using Commercially Available Accelerometers to Monitor Upper Extremity Home Practice With Persons Post-stroke: A Secondary Data Analysis
Authors: de Castro Kate N. , Donoso Brown Elena V. , Miller Neilan Rachael , Wallace Sarah E. 
Published: April 2021

Background: Adherence to home practice rehabilitation programs is important for efficacy; however, adherence is challenging for many individuals post-stroke. Accelerometers have emerged as a potential means to support home practice. This secondary data analysis explored the use of a commercially available accelerometer with custom software to collect and analyze data to corroborate self-reported practice collected during a home program.Methods: The initial study was a single subject design trial that investigated the effect of preferred music listening on adherence to an upper extremity home practice program (Trial Number NCT02906956. ClinicalTrials.gov). The participants (n = 7) were post-stroke adults with aphasia and hemiparesis of the upper extremity. Participants completed home program exercises while wearing accelerometers and recorded practice times in a logbook. Data were collected, cleaned, processed, and analyzed to facilitate descriptive comparisons and clinical interpretations of accelerometer output data.Results: Across all participants, an average of 47% of data were captured and usable for analysis. Five out of seven participants self-reported longer practice times compared to accelerometer duration output by a mean of 66.5 s. Individual exercise set mean total angular velocity and standard deviation of acceleration demonstrated potential for use across time to monitor change.Conclusions: One challenge of integrating accelerometers into clinical practice is the amount of data loss and the steps for data processing. The comparisons of available accelerometer data to the self-reported logs, however, were generally representative. Future investigations should explore ways to increase data capture and accessibility of the data for feedback to the client and practitioner.
Cinquantenaire de la francophonie : le jubilé avant la traversée des siècles
Authors: Yongui Jean Paul 
Published: April 2021

La matrice originelle de la Francophonie est une idée de rassemblement dont la génialité a consolidé un mouvement associatif désormais cinquantenaire. Les institutions naissent des idées et se maintiennent par la vertu de la pensée constructive. Par conséquent, le cinquantième anniversaire de la Francophonie institutionnelle signifie d’abord que la force d’une idée a triomphé jusque-là de l’usure du temps. Ce demi-siècle convie ensuite à une cure de jouvence de la Francophonie, à une modernisation de ses institutions au premier rang desquelles l’Organisation internationale de la Francophonie, dans l’optique de pérenniser l’idéal de fraternité universelle par le partage de la langue française. Loin d’être un monde parfait, l’espace francophone souffre de dysfonctionnements qui l’exposent à des critiques fondées ou outrées. Dans l’encadrement de la théorie des régulations du sociolinguiste Paul Zang Zang, le présent article diagnostique les difficultés structurelles de la Francophonie. Aucun sujet n’est tabou : la langue française, la Charte d’Antananarivo 2005, la diffusion du livre francophone, le statut des langues autochtones, la crise des mobilités, la « francophobiphonie », l’humanitaire, le déficit de communication, les obstructions à l’inventivité. Au lendemain du cinquantenaire, la Francophonie devra faire face au défi de la traversée des siècles. Par le truchement de l’approche diachronique prospective, le présent article esquisse une palette de solutions destinées, dans l’immédiat, à préserver la symbiose absolue entre la Francophonie et la totalité du XXIème siècle. Objectivement, la gouvernance de la Francophonie du troisième millénaire ne peut rester captive de la rhétorique et des méthodes des années 1970. Par conséquent, le basculement du monde dans le XXIème siècle oblige la Francophonie institutionnelle à opérer sa propre transfiguration. Le présent article préconise ainsi une présence télévisuelle plus audacieuse de la noosphère francophone sur une planète Terre où Internet et la téléphonie mobile ont exacerbé la polyphonie des idiosyncrasies et des cultures. Dans ce monde nouveau proposé par l’actuel millénaire, le destin de la langue française s’accomplit par l’infiniment petit, avec les nanotechnologies, et via l’infiniment grand exploré par les technologies astronautiques. Forts de ce constat et faisant écho à la théorie des régulations, de nombreux chercheurs invitent à intégrer les fonctions cybernétiques dans les stratégies futures de diffusion du français.
Is Francophonie a cultural common ?
Authors: Micaëlli Jean-Pierre 
Published: April 2021

Les catégories économiques peuvent faire plus que qualifier un pan de la francophonie contemporaine. Elles peuvent aider à la penser. Ainsi, cet article présentera comment le cadre théorique d'Elinor Ostrom développé pour analyser les biens naturels communs (commons) présente un intérêt pour comprendre ce qu'est un commun culturel ; la francophonie en étant une forme particulière. Ce bien constitue le sujet et le collectif, repose sur une croissance continue du fonds culturel, est étendu et extensible, et se veut l'objet de communautés créatives. Certaines questions relatives à la francophonie contemporaine seront ensuite abordées à travers ce prisme. Celle-ci sera appréhendée comme un commun culturel à la fois résiliaire, résilient, et dont la gouvernance suppose un véritable cocktail institutionnel autrement plus complexe que celui mis en œuvre pour gérer les communs naturels.
La francophonie en Chine : perspectives linguistique et culturelle
Authors: Zhang Li 
Published: April 2021

La francophonie connaît un développement rapide sur les plans linguistique et culturel en Chine depuis des années, qui se traduit par l’essor de l’enseignement du français dans les universités chinoises et des structures privées, la formation des plateformes des échanges culturels en Chine. Les dynamiques de cette prospérité proviennent de plusieurs parties : la Chine, la France, la Francophonie et aussi leur même conception de la culture. Le développement de la francophonie en Chine sera maintenu d’autant qu’il existe des potentialités de coopération culturelle entre la Chine et l’OIF en Afrique.
Sinergitas Antar Perguruan Tinggi Dalam Pelaksanaan Workshop Penulisan Jurnal Nasional Dan Internasional Secara Daring
Authors: Hamid Nasrullah  , Ari Waluyo  , K Prihartono Aksan Halim  , Wenny Marlini  , Uswatun Khasanah  , Wakhid Yuliyanto  
Published: April 2021

Sinergitas antar perguruan tinggi menjadi sebuah titik solusi bersama dalam mendorong para akademisi dalam mempublikasikan hasil riset para dosen/peneliti. Hal tersebut dapat terealisasi dengan saling berkomunikasi antar perguruan tinggi dengan mengadakan sebuah kegiatan. Kegiatan tersebut adalah pelaksanaan Workshop Nasional dengan Tema tips & trik tembus jurnal terakreditasi sinta dan workshop penulisan jurnal internasional bereputasi. Metode pelaksanaan kegiatan melalui aplikasi zoom meting sehingga dapat dijangkau dari berbagai daerah mulai dari sabang sampai merauke. Hasil polling zoom dari jumlah total 122 peserta yang mengisi dengan satu item pertanyaan tentang kepuasan peserta terhadap penyelenggaraan kegiatan menunjukkan jawaban peserta yang mengisi pada item sangat puas porsentasenya 62% dengan jumlah responden 76, selanjutnya pada item puas porsentasenya 37% dengan jumlah responden yang menjawab 45, selanjutnya item kurang puas porsentasenya 1% dijawab 1 responden dan tidak puas porsentase yang menjawab 0% responden. Dampak dari kegiatan tersebut adalah setiap lembaga di perguruan tinggi dapat memberika workshop pelatihan jurnal dilingkungan perguruan tinggi masing-masing 0.
Balkan Savaşları Esnasında Alman Salib-i Ahmer (Kızılhaç) Cemiyeti’nin İstanbul ve Edirne’de Yürüttüğü Sağlık Çalışmaları
Authors: Şimşek Muttalip 
Published: April 2021

1864’te imzalanan Cenevre Sözleşmesi’yle birlikte cephelerde askerî sağlık hizmetlerinin mükemmel bir şekilde yapılması anlayışı gelişmeye başlamış ve Avrupa’nın farklı ülkelerinde birbiri ardına Kızılhaç cemiyetleri kurulmuştu. Bunlardan birisi de Alman Kızılhaç teşkilatıdır ve bu kuruluş sadece Almanya’da değil dünyanın farklı bölgelerinde meydana gelen savaşlarda din ve milliyet ayrımı yapmaksızın cephelerde sağlık çalışması yürütmüştür. Alman Kızılhaçı özellikle Trablusgarp Savaşı (1911- 12), Balkan Savaşları (1912-13) ve Birinci Dünya Savaşı (1914-18) esnasında doktor, hemşire ve hastabakıcılardan oluşan ekiplerle Osmanlı cephelerinde hizmet etmiştir.Bu çalışmada, öncelikle Alman Salib-i Ahmer Cemiyeti’nin Balkan Savaşları’nın başlamasıyla birlikte hem Osmanlı Devleti’ne, hem de Balkan ülkelerine sağlık ekibi göndermek için nasıl bir seferberlik yürüttüğü açıklanacaktır. Daha sonra, sağlık ekiplerinin Almanya’daki üniversitelerde görev yapan tecrübeli doktorların idaresi altında uzman sağlık personeliyle birlikte İstanbul ve Edirne’de yürüttükleri çalışmalar detaylı bir şekilde değerlendirilecektir. Bunların yanında, Türk askerinin cephede oldukça zor şartlarda savaşmasına bağlı olarak ortaya çıkan kangren vakaları ve diğer ağır hastalıklara karşı verdiği mücadele ve Alman sağlık ekibinin Hilal-i Ahmer Cemiyeti’yle birlikte bu alanda yürütmeye çalıştığı hizmetler ortaya konacaktır. Ayrıca, Alman sağlık ekiplerinin kayıtları ışığında, tedavi edilen hastalara dair sayısal bilgiler verilerek, salgın hastalıklarla mücadele ve Ayastefanos (Yeşilköy) Karantina Merkezi’nin çalışmaları da burada detaylı bir şekilde değerlendirilecektir.