bluuebunny/crossref_metadata_2025_split huggingface dataset:
HIPTCN: Prospective Observational Study of Hypocoagulated Head Trauma Patients with Normal Admission Computed Tomography Scan
Authors: Duarte-Batista Pedro , Farinha Nuno Cubas , Marques Renata , Pinheiro João Páscoa , Silva João , Tuna Rui , Reis José Hipólito , Antunes Cristiano , Machado Maria João , Lemos Samuel Sequeira , Branco Jessica , Roque Diogo , Simão Diogo , Simas Nuno , Teixeira Wilson , Felício Cátia , Ferreira Miguel , Cunha Eduardo , Rocha Luís , Figueiredo Gonçalo , Noronha Carolina , Pinto Vasco , Silva Filipe , Ferreira Ana , Sousa Osvaldo 
Published: June 2021

Introduction: Our national protocol for traumatic brain injury dictates that hypocoagulated patients with mild trauma and initial tomography scan with no intracranial traumatic changes must be hospitalized for 24 hours and do a post-surveillance tomography scan. The main goal of this study was to evaluate the clinical relevance of these measures.Material and Methods: A prospective observational study was undertaken in four hospitals. Adult hypocoagulated traumatic brain injury patients with a normal tomography scan were included. The main outcomes evaluated were rate of delayed intracranial hemorrhage, rate of admission in a neurosurgical department, rate of complications related with surveillance and rate of prolonged hospitalization due to complications. An analysis combining data from a previously published report was also done.Results: A total of 178 patients were included. Four patients (2.3%) had a delayed hemorrhage and three (1.7%) were hospitalized in a neurosurgery ward. No cases of symptomatic hemorrhage were identified. No surgery was needed, and all patients had their anticoagulation stopped. Complications during surveillance were reported in seven patients (3.9%), of which two required prolonged hospitalization.Discussion: The rate of complications related with surveillance was higher than the rate of delayed hemorrhages. The initial period of in-hospital surveillance did not convey any advantage since the management of patients was never dictated by neurological changes. Post-surveillance tomography played a role in deciding about anticoagulation suspension and prolongation of hospitalization.Conclusion: Delayed hemorrhage is a rare event and the need for surgery even rarer. The need for in-hospital surveillance should be reassessed.
Pelatihan Teknik Menulis Best practice Bagi Kepala Sekolah di PKG Banjarmasin Tengah
Authors: Novitawati Novitawati , Purwanti Ratna - , Sulaiman Sulaiman , Prastitasari Herti 
Published: June 2021

Tujuan kegiatan pelatihan untuk meningkatkan pengetahuan kepala sekolah dalam menulis Best Practice. Metode yang digunakan dalam pelatihan ini meliputi ceramah, tanya jawab dan diskusi. Peserta pengabdian adalah kepala sekolah TK di lingkungan PKG Banjarmasin Tengah yang berjumlah 37 peserta. Kegiatan pengabdian masyarakat ini dilakukan pada bulan November tahun 2020 selama dua hari. Kegiatan pelatihan berjalan lancar, peserta mendapatkan pengetahuan tentang penulisan Best practice mengenai orisinalitas, inovatif, elaborative, inspiratif, empirik dan aplikatif. Hasil Best practice dapat direflikasi, dimanfaatkan dan atau dikembangkan baik di sekolah sendiri maupun di sekolah lain. Kegiatan pengabdian seperti ini dapat dilakukan secara rutin baik di gugus yang sama maupun di gugus yang berbeda dengan sasaran Kepala sekolah yang benar-benar membutuhkan pelatihan penulisan Best Practice. The purpose of the workshop activities is to increase the principal's knowledge in writing Best Practice. The methods used in this workshop include lectures, question and answer and discussion. The community service participants were the kindergarten headmaster in the PKG Banjarmasin Tengah, totalling 37 participants. This community service activity was carried out in November 2020 for two days. The workshop activities run smoothly, and participants get knowledge about writing best practices regarding originality, innovation, elaborative, inspirational, empirical and applicative. Best practice results can be replicated, utilized, or developed in their schools and other schools. Community service activities like this can be carried out routinely in the same cluster or different clusters with the target of the principal who needs a best-practice writing workshop.
Upaya Peningkatan Interaksi Sosial Pada Penerima Manfaat di Panti Sosial Bina Laras Budi Luhur
Authors: Azkia Laila , P Reski , Alfisyah Alfisyah 
Published: June 2021

Tujuan dari pengabdiaan masyarakat ini adalah meningkatkan interaksi sosial pada penerima manfaat dan sebagai upaya rehabilitasi sosial penyandang disabilitas mental melalui komunikasi dua arah. Pengabdian ini dilaksanakan oleh tim pengabdi yang terdiri atas 3 orang dosen dan juga beberapa orang mahasiswa. Metode pelaksanaan pengabdian ini adalah dengan cara partisipatoris. Sasaran pengabdian ini adalah penerima maanfaat atau disebut juga klien atau penghuni Panti di Panti Sosial Bina Laras Budi Luhur. Tim pengabdi melakukan komunikasi dua arah dengan penerima manfaat. Komunikasi yang dilakukan merupakan upaya peningkatan interaksi sosial penerima manfaat. Setelah dilakukan komunikasi dua arah, beberapa penerima menjadi lebih mudah dalam mengutarakan apa yang dipikirkan dan apa yang dirasakan. Melalui kegiatan ini diperoleh bahwa penerima manfaat mampu berinteraksi dengan baik dengan orang di luar Panti. Selanjutnya penerima manfaat diharapkan dapat bersosialisasi dengan masyarakat luas nantinya setelah keluar dari Panti. This community service aims to increase social interaction with beneficiaries and as an effort to social rehabilitation of persons with mental disabilities through two-way communication. This service was carried out by a service team consisting of 3 lecturers and also several students. The method of implementing this service is participatory. The target of this service is the beneficiaries or also known as clients or residents of the orphanage at the Bina Laras Budi Luhur Social Home. The service team communicates in two ways with the beneficiaries. The communication carried out to increase the social interaction of the beneficiaries. After two-way communication, some recipients find it easier to express what they think and what they feel. Through this activity, it was found that the beneficiaries were able to interact well with people outside the orphanage. Furthermore, beneficiaries are expected to be able to socialize with the wider community after leaving the orphanage.
THE IMPLEMENTATION OF PROBLEM BASED LEARNING MODEL WITH STEM (SCIENCE, TECHNOLOGY, ENGINEERING, MATHEMATICS) APPROACH TO TRAIN STUDENTS’ SCIENCE PROCESS SKILLS OF XI GRADERS ON CHEMICAL EQUILIBRIUM TOPIC
Authors: Awalin Nabila Aurelia , Ismono Ismono 
Published: June 2021

This study aims to determine the improvement of learning outcomes and students’ science process skills by implementation PBL (Problem Based Learning) model with STEM (Science, Technology, Engineering, Mathematics) based on chemical equilibrium topic. The method in this research is quantitative descriptive with One-Group Pretest-Postest design. The subjects of this study were students of Mathematics and Natural Sciences XI graders in State Senior High School 1 Pulung, Ponorogo Regency. Data method is; observation, questionnaires, and tests. Technical data analysis used is; analysis of study results data, analysis of observations of learning implementation, analysis of student activities, analysis of learning outcomes completeness, and analysis of student responses. The results in this study were: (1) the mean percentage of the implementation of PBL model based on STEM in the chemical equilibrium topic was 89.26%; (2) the category of improvement for all indicators of Science Process Skills observing and conclusion that respectively 0.82 and 0.89 are included in the high category, for the skills to formulate problems, formulate hypotheses, determine variables, and analyze data respectively of 0.64 ; 0.42; 0.67; 0.68 and can be categorized as moderate; (3) the learning outcomes of students in the realm of knowledge have increased classically with n-gain of 0.62 in the moderate category; and the last (4) learning by implementation the STEM-based PBL model on chemical equilibrium material received a positive response from students based on the results of the questionnaire, the percentage was 83%.
Comprehensive Operational Assessment Eliminates Significant Lost Time on a 3-Year Development Project in Nigeria
Authors: Akinyamoju Benedict , Irving Don , Olofin Abiodun , Browne Christopher , Loo Enrique , Greenwood Jeremy 
Published: June 2021

Abstract
A 3 year, 23 well project drilled by a major operator in Nigeria was challenged to develop methodologies to optimize every aspect of drilling for a development project to reduce total project time and costs.
The team of operator and service company personnel created an approach that systematically examined and challenged the efficiency of all tasks. They then developed and implemented innovative methods to save time by both analyzing repetitive, lengthy, or troublesome operations and challenging many status quo rig activities. The culture of continually challenging the causes of invisible lost time (ILT) that developed resulted in the creation of several critical performance improvement methodologies each of which are explained in detail.
The multiple focus areas where process improvements were made included hole cleaning efficiencies, optimizing the ROP to deliver shortest well time from drilling out the casing shoe to landing the next casing, anti-collision practices to drill out conductors with a separation factor of less than 1.0, BHA design efficiencies for equipment standardization and faster make up and break down times, managing differential sticking risks, improving survey times, and developing best practices to side-track with a point-the-bit Rotary steerable system. Exact times were tracked to establish the required baselines and drilling optimization services were introduced to modify the drilling practices to reach the technical limit.
The technical limit for ROP was achieved and best practices developed in this environment for effective hole cleaning, ease of tripping, and improved tripping speeds of the BHA at the end of every run saved 38.25 days over 15 wells. Average ROP's were improved by 48% in the 17 ½" section and 57% in the 12 ¼" section. The new anti-collision methodology saved 5 hours per well. BHA assembly and tool download efficiencies saved 11.47 days. Wellbore strengthening techniques prevented seepage losses and reduced stuck pipe events. Surveying improvements saved 11.78 days and new sidetracking practices saved 5 hours per sidetrack. Tasks that could be done in parallel to the critical path were identified and tasks on the critical path were performed more efficiently. ILT elimination in drilling processes saved a total of 96 days of rig time over an established performance baseline during this 23 well project. The operator set two records for the fastest drilled and completed conventional offshore wells in Nigerian history.
A Reversible shearing DNA-based tension probe for cellular force measurement
Authors: Li Hongyun , Hu Yuru , Sun Feng , Chen Wei , Liu Zheng 
Published: June 2021

Abstract
Cells can sense and respond to molecular forces ranging from a few pN to tens of pN through mechanosensitive receptors with an astounding diversity of mechanisms. DNA-based molecular tension sensors have been instrumental in studying the importance of mechanical forces in many biological systems. However, the respective shortcomings of these sensors, for instance, the irreversible rupture of tension gauge tether (TGT) under force and relatively limited dynamic range of the hairpin probes, limited our understanding of the molecular details of mechano-chemo-transduction in living cells. Here, we developed a reversible shearing DNA-based tension probe (RSDTP) for probing molecular pN-scale forces between 4-60 pN transmitted by cells. Using RSDTPs to study integrin-mediated mechanotransduction, we could real-time distinguish the differences of force-bearing integrins without perturbing adhesion biology in living cells.
A Pilot Study of Possible Anti-Inflammatory Effects of The Specific Carbohydrate Diet in Children with Juvenile Idiopathic Arthritis
Authors: Berntson Lillemor 
Published: June 2021

Abstract
Background: To explore possible anti-inflammatory effects of the specific carbohydrate diet in children with juvenile idiopathic arthritis. This diet has shown anti-inflammatory effect in children with inflammatory bowel disease.Methods: Twenty-two patients with juvenile idiopathic arthritis (age 6.3–17.3 years), with ≤ 2 inflamed joints and an erythrocyte sedimentation rate < 30 mm/h, were included in this explorative study. Fifteen children completing four weeks on the diet were evaluated. A dietician introduced parents and children to the diet, and two follow-ups were performed during the intervention. Conventional laboratory tests and multiplex analyses of 92 inflammatory proteins were used. Short-chain fatty acids in faecal samples were examined.Results: The diet significantly decreased morning stiffness (p = 0.003) and pain (p = 0.048). Physical function, assessed through the child health assessment questionnaire, improved (p = 0.022). Arthritis improved in five of the seven children with arthritis; in those seven, multiplex analyses showed a significant decrease in nine inflammatory proteins, including TNF-alpha (p = 0.028), after four weeks. Faecal butyrate, analysed in all 15 participants, increased significantly (p = 0.020).Conclusion: The specific carbohydrate diet may have significant positive effects on arthritis in children with juvenile idiopathic arthritis, but further studies are needed.Clinical Trials Identifier: NCT04205500, 2019/12/17, retrospectively registered. URL:https://register.clinicaltrials.gov.
The Environmental-adjusted Energy Efficiency of China’s Construction Industry: A Three-stage Undesirable SBM-DEA Model
Authors: Chen Yufeng , Ma Lihua , Zhu Zhitao 
Published: June 2021

Abstract
Construction industry is a pillar industry of China's national economy but its problems of high energy consumption, high pollution and low energy efficiency is increasingly prominent. The study on the energy efficiency of construction industry is of great significance for improving development quality and achieving the goal of energy saving and emission reduction. In this paper, a three-stage undesirable SBM-DEA model was employed to measure the energy efficiency in construction industry during 2005 -2016. The CO2 directly emitted by the construction industry and indirectly emitted in the production of building materials were used as the undesirable output and the three-stage framework was employed to analyze and eliminate the influence of external environment. The empirical results showed that low efficiency of management in the construction industry is an important factor leading to the low level of energy efficiency in China’s construction industry. For the energy efficiency value before and after adjustment, the “high-high” provinces has made full use of the superior external environment by their high management level, while the “high-low” provinces needs to fully realize the potential in promoting energy efficiency of its external environment by improving its own management of construction industry. On the contrary, the “low-high” provinces need to improve the external environment to ease its restrictions on the level of management in the construction industry. Environmental factors and management level should be considered simultaneously for different provinces to improve energy efficiency of construction industry.
Different molecular markers to identify the fertility of sugar beet monogerm germplasm resources
Authors: Shi Haoqi , Pi Zhi , Wu Zedong 
Published: June 2021

Abstract
Experiments were conducted to validate different molecular markers associated with sugar beet breeding using available sugar beet monogerm germplasm resources to explore their effectiveness in different sugar beet populations. We used multiple primer pairs to amplify sugar beet monogerm sterile and maintainer lines in order to verify their polymorphism. For the nucleus Rf1 locus genotype enzyme digestion was also required to verify. The results showed that three pairs of primers, TR1, s17 and 11E8M4S, produced polymorphism when amplifying sugar beet sterile and maintainer lines; primers o7 and AB-18, although polymorphic, did not correlate significantly with sugar beet fertility; primer cpSSR-2 did not produce significant band differences when amplifying sterile and maintainer lines, however, the number of single nucleotide sequence repeats of base A needed to be further verified as a basis for differentiating sugar beet fertility. The polymorphism of 15 pairs of primers related to sugar beet fertility identification was verified and TR1, s17 and 11E8M4S could be used to differentiate sugar beet sterile lines from the maintainer lines and used for subsequent Marker-Assisted Selection (MAS).
The Spatial Distribution of Tree Populations and Its Policy Drivers in Medieval Areas of Cities. Case Studies From East-central Europe
Authors: Mizgajski Andrzej , Trzaskowska Ewa , Dubis Lidiya , Zajączkowski Dominik , Borysiak Janina 
Published: June 2021

Abstract
Trees in the densely built-up historical cores of cities play an important role in increasing the aesthetic values of the cityscape as well as lowering the effect of the urban heat island. The research aimed to determine the spatial distribution of tree populations in the medieval parts of cities according to local policy. The investigation included three cities in Central and Eastern Europe: Poznań and Lublin in Poland and Lviv in Ukraine. The oldest parts of these cities share similar origins, the same continental biogeographical region, and comparable climatic conditions.This study considered indicators of occurrence, density, species composition, and spatial distribution; and the number of trees planted since the political transition to democracy has also been considered, taking into account the composition of their species. Local policy documents on greenery management, revitalisation, and adaptation to climate change were analysed.The study identified different types of management concerning trees. In Poznań, trees are actively introduced in public spaces, but private backyards are managed by their owners. In Lublin, although there are relatively few new plantings, there is the largest share of trees in the backyards and self-seeding is common. In Lviv, there are new plantings in private and public spaces. Lviv is distinguished by its large share of native trees, with naturally shaped crowns, and in Poznan and Lublin, new plantings include artificially shaped, small spherical crowns. The local policy documents don't contain operational directives regarding the cultural, environmental, social, and technical conditions for new planting.
ENgage YOung people earlY (ENYOY): A mixed-method study design for a digital transdiagnostic clinical – and peer- moderated treatment platform for youth with beginning mental health complaints in the Netherlands.
Authors: Doorn Marilon van , Popma Arne , Amelsvoort Thérèse van , McEnery Carla , Gleeson John , Öry Ferko , Jaspers Monique , Alvarez-Jiminez Mario , Nieman Dorien 
Published: June 2021

Abstract
• Background: The onset of mental disorders typically occurs between the ages of 12 and 25, and the burden of mental health problems is the most consequential for this group. Indicated prevention interventions to target individuals with subclinical symptoms to prevent the transition to clinical levels of disorders, even leading to suicide, have shown to be effective. However, the threshold to seek help appears to be high. Digital interventions could offer a solution, especially during the Covid-19 pandemic. This implementation study will investigate the digital indicated prevention intervention ENgage YOung people Early (ENYOY), the Dutch version of the original Moderated Online Social Therapy Platform (MOST+) from Australia. In addition, the relationship between stress biomarkers, symptoms and outcome measures of youth using the platform will be investigated in this study.• Methods: The MOST+ platform will be adapted, translated and developed for the situation in the Netherlands in collaboration with a Youth Panel. A prospective cohort of 125 young people (12-25 years) with beginning mental health complaints will be on the platform and followed for a year, of which 10 participants will have an additional smart watch and 10 participants will be asked to provide feedback about the platform. Data will be collected at baseline and after 3, 6 and 12 months. Outcome measures are Psychological Distress assessed with the Kessler Psychological Distress Scale (K10), Social and Occupational Functioning Assessment Scale (SOFAS), positive mental health indicators measured by the Positive Health Instrument, stress biomarkers with a smart-watch, website journeys of visitors, and feedback of youth about the platform. It will be a mixed-method study design, containing qualitative and quantitative measures. • Discussion: This trial will specifically address young people with emerging mental health complaints, and offers a new approach for treatment in the Netherlands. Considering the waiting lists in (Child and adolescent)-psychiatry and the increase in suicides among youth, early low-threshold and non-stigmatizing help to support young people with emerging psychiatric symptoms is of crucial importance. Moreover, this project aims to bridge the gap between child and adolescent and adult psychiatry.• Trial registration: Netherlands Trial Register ID NL8966, retrospectively registered.
Dynamic response of multi-degree-of-freedom systems with a Coulomb friction contact under harmonic excitation
Authors: Marino Luca , Cicirello Alice 
Published: June 2021

Abstract
This paper investigates the steady-state response of a multi-degree-of-freedom (MDOF) system with a Coulomb contact to harmonic excitation. Although discrete MDOF models are commonly used at early design stages to analyse the dynamic performances of engineering structures, the current understanding of the friction damping effects on MDOF behaviour is still limited due to the absence of analytical solutions. In this contribution, closed-form expressions of the continuous time response, the displacement transmissibility and the phase angle of each mass of the system are derived and validated numerically for 2DOF and 5DOF systems. Moreover, the features of the analytical response are investigated, obtaining the following results: (i) the determination of the minimum amounts of friction for which the resonant peaks become finite and (ii) for which stick-slip motion can be observed at high frequencies; (iii) an equation for the evaluation of invariant points for the displacement transmissibilities; (iv) a better understanding of phenomena such as the inversions of the transmissibility curves and the onset of additional resonant peaks due to the permanent sticking of the mass in contact. All these results show that MDOF systems exhibit significantly different dynamic behaviours depending on whether the friction contact and the harmonic excitation are applied to the same or different masses.