bluuebunny/crossref_metadata_2025_split huggingface dataset:
Taste receptors in chronic rhinosinusitus, what is the evidence? A systematic review
Authors: Chen Jonathan H. , Song Christopher I. , Hura Nanki , Saraswathula Anirudh , Seal Stella M. , Lane Andrew P. , Rowan Nicholas R. 
Published: December 2021

AbstractBackgroundBitter and sweet taste receptors (T2Rs and T1Rs), respectively, are involved in the innate immune response of the sinonasal cavity and associated with chronic rhinosinusitis (CRS). Growing evidence suggests extraoral TRs as relevant biomarkers, but the current understanding is incomplete. This systematic review synthesizes current evidence of extraoral taste receptors in CRS.MethodsPubMed, Embase, Cochrane, Web of Science, and Scopus were reviewed in accordance with Preferred Reporting Items for Systemic Reviews and Meta‐Analyses guidelines and included studies of genotypic and phenotypic T2R/T1R status in CRS patients.ResultsTwenty‐two studies with 3845 patients were included. Seventeen studies evaluated genotype and 10 evaluated taste phenotypes. Four of 6 studies examining the haplotype distribution of the T2R, TAS2R38, demonstrated increased AVI/AVI haplotype (“nontaster”) frequency in CRS. Meanwhile, 2 studies demonstrated decreased bitter sensitivity in CRS with nasal polyposis (CRSwNP), whereas 3 other studies reported decreased bitter sensitivity only in CRS without nasal polyposis (CRSsNP). Findings regarding sweet sensitivity were mixed. Three studies with cystic fibrosis patients (n = 1393) were included. Studies investigating the association between clinical outcomes and TAS2R38 alleles were limited, but the nonfunctional combination of AVI/AVI was associated with increased utilization of sinus surgery and, in CRSsNP patients, with poorer improvement of symptoms postoperatively.ConclusionBoth genotypic and phenotypic assessments of T2Rs suggest a potential association with CRS, particularly CRSsNP. However, limited evidence and mixed conclusions cloud the role of T2Rs in CRS. Future investigations should aim to increase diverse populations, broaden institutional diversity, examine T1Rs, and utilize uniform assessments.
Dynamics of Quantum Correlation and Entropic Uncertainty in Spin‐12$\frac{1}{2}$ Alternating Transverse Ising Model
Authors: Jiang Tian‐Yi , Fang Yu‐Yan , Li Ying‐Hong , Xu Xin‐Ye , Liu Jin‐Ming 
Published: December 2021

AbstractBy implementing the quantum renormalization group method, the effective Hamiltonian of the spin‐ Ising model with regularly altering strengths of both the magnetic fields and the exchange couplings are first derived analytically. Then, tripartite quantum discord (QD) and entropic uncertainty (EU) of the Ising model and their quantum phase transitions are investigated. Moreover, the quantum critical points and correlation length exponents of the model are analyzed, and both the block–block EU and the site–site EU are discussed through numerical calculations. It is found that under the system size increasing, the first derivatives of both tripartite QD and block–block EU show nonanalytic and scaling behaviors near the critical point. Furthermore, the strong quantum correlations among multi‐particles do not necessarily lead to the decrease of EU, as the site–site EU in the vicinity of the critical point increases due to competitions among quantum correlations. The findings may offer new insights into utilizing EU as an observable of the quantum phase transitions.
Measurement of Photonic Topological Charge Using a Generalized Ring Pearcey Phase
Authors: Zhou Xiaoyan , Pang Zihao , Zhao Daomu 
Published: December 2021

AbstractAn effective method capable of measuring the topological charges of optical vortex beams by using a generalized ring Pearcey (GRP) phase is proposed theoretically and demonstrated experimentally in this paper. The number and orientation of fringes in the diffraction patterns respectively reveal the modulus and sign of topological charges. One can also tell the sign by observing the rotation of fringes during propagation. Moreover, the measurement of high‐order topological charges is shown to be significantly affected by the elliptical parameter in the GRP phase. Finally, the physical principle of these measurements is unveiled by applying the stationary phase approach. This work offers an alternative way of evaluating the photonic topological charges in vortex beams.
Synthesis of ultraviolet curable bisphenol‐based epoxy acrylates and comparative study on its physico‐chemical properties
Authors: D. Desai Prashil , N. Jagtap Ramandand 
Published: December 2021

AbstractPhotocuring resins have emerged as cutting‐edge technology in coatings, adhesives, composites, additive manufacturing, and so forth. In the present work, different bisphenol, namely A, F, and S, were used to synthesize low molecular weight epoxy resin, which was further reacted with acrylic acid monomer to form bisphenol‐based epoxy acrylate (BEA). The BEA resins were formulated using reactive diluents, trimethylolpropane triacrylate, and hexanediol diacrylate in the ratio of 0–40 wt% at the increment of 10 wt% alongside a fixed quantity photoinitiator. These resins were then cast into dumbbell‐shaped specimens by irradiating them under ultraviolet (UV) light. The structural elucidation of BEA resins was performed using Fourier transform infrared, nuclear magnetic resonance, and UV–Vis spectroscopy. The formulated resins were also studied for their rheological properties. Further, the UV cured specimens were evaluated for mechanical, thermal, contact angle, and extent of curing. These outcomes were utilized for establishing the structure–property relationship based on the functionality, reactivity, and molecular structure of synthesized BEA resins, which controllers the design architecture and cross‐linking density of UV‐cured specimens.
Fabrication and thermomechanical properties of carbonized Luffacylindrica‐reinforced high‐density polyethylene composites
Authors: Ioannou Ioannis , Kyriacou Paraskevas , Pantelas Marios , Pashalidis Ioannis , Makris John , Rallis Spyros , Kostas Giachalis , Avraam Kyriakos , Krasia‐Christoforou Theodora 
Published: December 2021

AbstractThe lifecycle of a material and the environmental trace is becoming a dominant parameter on material's selection process. The present study focuses on the fabrication and thermomechanical characterization of fully recycled composite materials based on high‐density polyethylene (HDPE) reinforced with bio‐natural inclusions of carbonized Luffa cylindrica (c‐LC). Materials fabrication was realized by applying the twin roll mill process, which enabled the production of a series of polymer composites with variable c‐LC content. The morphological and thermomechanical characteristics were investigated by means of scanning electron microscopy and dynamic mechanical analysis, respectively. Morphological results indicate a reinforcing geometry of the inclusions, while the thermomechanical characterization verifies the reinforcement of HDPE thermoplastic with the biochar inclusions thus paving the way to the use of such fully‐recycled biochar thermoplastic composite materials on structural and semi‐structural applications.
Disclosing the relationship between citation structure and future impact of a publication
Authors: Huang Shengzhi , Qian Jiajia , Huang Yong , Lu Wei , Bu Yi , Yang Jinqing , Cheng Qikai 
Published: December 2021

AbstractEach section header of an article has its distinct communicative function. Citations from distinct sections may be different regarding citing motivation. In this paper, we grouped section headers with similar functions as a structural function and defined the distribution of citations from structural functions for a paper as its citation structure. We aim to explore the relationship between citation structure and the future impact of a publication and disclose the relative importance among citations from different structural functions. Specifically, we proposed two citation counting methods and a citation life cycle identification method, by which the regression data were built. Subsequently, we employed a ridge regression model to predict the future impact of the paper and analyzed the relative weights of regressors. Based on documents collected from the Association for Computational Linguistics Anthology website, our empirical experiments disclosed that functional structure features improve the prediction accuracy of citation count prediction and that there exist differences among citations from different structural functions. Specifically, at the early stage of citation lifetime, citations from Introduction and Method are particularly important for perceiving future impact of papers, and citations from Result and Conclusion are also vital. However, early accumulation of citations from the Background seems less important.
ZnV2O4‐Textured Carbon Composite Contacting a ZIF‐8 MOF Layer for a High Performance Non‐Aqueous Zinc‐Ion Battery
Authors: Naskar Souvik , Deepa Melepurath 
Published: December 2021

AbstractNon‐aqueous zinc‐ion battery (ZIB) comprising a zinc vanadate@textured carbon (ZnV2O4@TC) composite cathode and Zn‐anode demonstrates an improved Zn(II)‐ion storage response, in terms of cyclability (230 mAh g−1 after 200 cycles, 84.9 % retention) and rate capability compared to pristine ZnV2O4 (175 mAh g−1 after 200 cycles, 45.4 % retention). TC reduces the aggregation of ZnV2O4 nanoparticles, allows abundant interaction with electrolyte, affords short ion diffusion pathways, serves as electrically conducting interconnects, and buffers the volume alterations thus imparting rapid kinetics and improved cycling stability. This performance is even better by the inclusion of a ZIF‐8 metal‐organic framework (MOF) layer at the separator, facing the cathode. ZIF‐8 due to its nanoporous structure encompassing Zn−N based polyhedral clusters, efficiently confines Zn(II) ions at cathode during discharge and allows their facile diffusion through its open channels during charge thus maximizing Zn(II) ion storage capacity and reversibility and its highly crystalline robust structure also enhances the ZIB durability. This achievement is in line with the development of cost‐effective, easily implementable non‐aqueous ZIB that avoids the issues associated with aqueous electrolyte of limited potential stability window, corrosion of current collectors over time, and cell degradation and also offers long term stability and capacity.
Evaluation of approaches for accommodating interactions and non‐linear terms in multiple imputation of incomplete three‐level data
Authors: Wijesuriya Rushani , Moreno‐Betancur Margarita , Carlin John B. , De Silva Anurika P. , Lee Katherine J. 
Published: December 2021

AbstractThree‐level data structures arising from repeated measures on individuals clustered within larger units are common in health research studies. Missing data are prominent in such studies and are often handled via multiple imputation (MI). Although several MI approaches can be used to account for the three‐level structure, including adaptations to single‐ and two‐level approaches, when the substantive analysis model includes interactions or quadratic effects, these too need to be accommodated in the imputation model. In such analyses, substantive model compatible (SMC) MI has shown great promise in the context of single‐level data. Although there have been recent developments in multilevel SMC MI, to date only one approach that explicitly handles incomplete three‐level data is available. Alternatively, researchers can use pragmatic adaptations to single‐ and two‐level MI approaches, or two‐level SMC‐MI approaches. We describe the available approaches and evaluate them via simulations in the context of three three‐level random effects analysis models involving an interaction between the incomplete time‐varying exposure and time, an interaction between the time‐varying exposure and an incomplete time‐fixed confounder, or a quadratic effect of the exposure. Results showed that all approaches considered performed well in terms of bias and precision when the target analysis involved an interaction with time, but the three‐level SMC MI approach performed best when the target analysis involved an interaction between the time‐varying exposure and an incomplete time‐fixed confounder, or a quadratic effect of the exposure. We illustrate the methods using data from the Childhood to Adolescence Transition Study.
Naringenin protects swine testis cells from bisphenol A‐induced apoptosis via Keap1/Nrf2 signaling pathway
Authors: Chen Huijie , Chen Jianqing , Shi Xu , Li Lu , Xu Shiwen 
Published: December 2021

AbstractBisphenol A (BPA) has caused serious pathologies in varying organs of humans and animals, especially reproductive organs. Naringenin (NRG) is a flavanone compound that has shown protective effects against several environmental chemicals through suppression of oxidative stress and activation of nuclear factor erythroid 2‐related factor 2 (Nrf2) pathway. Herein, we described the discovery path of NRG inhibition on apoptosis in BPA exposed swine testis (ST) cells through targeting Kelch‐like ech‐associated protein (Keap1). We found that NRG could specifically bound to the active residues of DGR domain in Keap1, thereby activating Nrf2 signaling pathway, and then increasing the levels of SOD, GPx and CAT, and finally inhibiting oxidative stress and mitochondrial apoptosis induced by BPA in ST cells. Altogether, our results showed that NRG inhibits oxidative stress and mitochondrial apoptosis induced by BPA in ST cells by targeting Keap1/Nrf2 signaling pathway, indicating that NRG could serve as an antagonistic therapy against BPA.
The contribution of the Eco‐Management and Audit Scheme to the environmental performance of manufacturing organisations
Authors: Marrucci Luca , Daddi Tiberio 
Published: December 2021

AbstractEnvironmental management systems' effects on organisations' environmental performance are still an open issue. This study assesses the contribution of the Eco‐Management and Audit Scheme (EMAS) to corporate environmental performance. The study also investigates the correlation between the environmental and economic performance of organisations. Environmental indicators were collected from 268 environmental statements of Italian manufacturing firms, while economic indicators were obtained from the Orbis database. After analysing around 5000 indicators, the results indicated a slight deterioration in some organisations' environmental performance and an improvement in the economic performance. No correlation was found between environmental and economic performance. Moreover, around 60% of the organisations are not fully compliant with the standard requirements linked to the environmental statements. The results question the positive effects of environmental management systems on environmental performance.
Unfitness to stand trial and fetal alcohol spectrum disorder: Understanding and responding to FASD within the criminal justice system in New Zealand
Authors: Brookbanks Warren , McGinn Valerie , Chu Joanna Ting Wai 
Published: December 2021

AbstractFetal alcohol spectrum disorder (FASD) is an increasingly important issue in the New Zealand (NZ) Criminal Justice System (CJS). FASD may impact an offender's ability to participate meaningfully in the trial process, giving rise to the issue of unfitness to stand trial. Capacity to apprehend, comprehend, participate in, make decisions about and communicate within legal process intersect with the complexity and severity of charges. Courts are required to make a nuanced analysis of multiple and complex factors, merging medical and legal expertise into decisions made. We explore the nature of FASD and its implications for criminal justice in NZ. The legal and clinical issues in relation to fitness and FASD will be discussed.
Oil Cakes as Sustainable Agro‐Industrial Feedstock for Biocarbon Materials
Authors: Siva Sankari M. , Vivekanandhan S. , Misra M. , Mohanty A. K. 
Published: December 2021

AbstractThe demand for vegetable oil is increasing for both food and non‐food applications, which leads to the generation of a huge amount of oil cakes. The rising annual production requires alternative applications for sustainable operations of oil mills, especially those involved in non‐edible oil production. Hence, the value‐added uses of oil cakes such as environment remediation (metal absorption), composite fabrication (as fillers, reinforcements), nanoparticle synthesis (as reducing and stabilizing agent), and production of carbonaceous materials (as carbon source) were extensively explored in recent years. Among them, the thermochemical conversion of oil cakes into carbonaceous materials (biochar and activated carbon) received great interest as the demand for biocarbon materials increases exponentially. Oil cake‐derived biocarbon materials found a wide range of technological applications. With this perspective, recent developments in oil cake‐derived carbon materials and their diverse applications are reviewed.
NiAl‐LDH In‐Situ Derived Ni2P and ZnCdS Nanoparticles Ingeniously Constructed S‐Scheme Heterojunction for Photocatalytic Hydrogen Evolution
Authors: Wu Youlin , Li Youji , Zhang Lijun , Jin Zhiliang 
Published: December 2021

AbstractSurface modification of photocatalytic materials is a good choice for improving semiconductor activity. Simple surface modification strategy and abundant active site construction are the key factors to improve photocatalytic activity. Take NiAl‐LDH as the matrix, perform partial phosphating, and use the spatial confinement effect to generate highly dispersed Ni2P. Ni2P does not exist independently but on the 3D NiAl‐LDH's surface. The introduction of NiAl‐LDH‐P can improve the utilization of Zn0.5Cd0.5S on solar energy and speed up the transfer rate of photogenerated carriers. Ni2P makes the active sites of phosphide more abundant, and the unique electron distribution of phosphide is conducive to photon capture, thus accelerating the hydrogen precipitation rate in the composite photocatalyst. Partial phosphating retains the 3D framework of hydrotalcite. The well‐dispersed 0D to 3D S‐scheme heterojunction hybrid material is composed of three‐dimensional nano‐flowers and tiny nano‐particles alternately formed by countless nano‐sheets. The multi‐dimensional structured composite photocatalyst has abundant active sites, large specific surface area, and strong proton adsorption capacity, thus exhibiting more excellent photocatalytic hydrogen evolution performance. The maximum hydrogen production of the composite photocatalyst under 5 W LED simulated visible light for 5 h can reach 1982.43 μmol (39.64 mmol g−1 h−1) and the apparent quantum efficiency reached 6.22 % at 475 nm. The construction of the Zn0.5Cd0.5S/NiAl‐LDH‐P S‐scheme heterojunction changes the hydrogen evolution site from Zn0.5Cd0.5S to Ni2P, so that the conduction band position of the composite photocatalyst becomes higher, the reduction ability is enhanced, and the hydrogen evolution The site changed from Zn0.5Cd0.5S to Ni2P, which is more conducive to the generation of hydrogen, thereby improving the activity and stability of hydrogen production. The space design of 0D and 3D provides new thinking for the design of the closely contacted S‐scheme heterojunction photocatalytic. The application of surface modification strategies and the construction of abundant active sites point out the direction for further improving the composite photocatalytic activity.
Single Step Electrochemical Semi‐Exfoliated S‐Doped Graphene‐Like Structures from Commercial Carbon Fiber as Efficient Metal‐Free Catalyst for Hydrogen Evolution Reaction
Authors: Ersozoglu M. Giray , Gursu Hurmus , Gumrukcu Selin , Sarac A. Sezai , Sahin Yucel 
Published: December 2021

AbstractThe hydrogen evolution reaction (HER) is the core of electrocatalysis and plays a crucial role in water splitting to obtain hydrogen. It has been inevitable to develop metal‐free catalysts in terms of sustainability, the environment, and economic feasibility. Carbon‐based materials are called metal‐free electrocatalysts and are regarded as one of the most promising candidates due to their abundant source, but they often show poor activity. The strategic aim of this study is to convert commercial carbon fiber into heteroatom‐doped graphene‐like surfaced fibers via an eco‐friendly and fast intercalation/semi‐exfoliation mechanism called Yucel's method. Furthermore, X‐ray photoelectron spectroscopy (XPS) verified that the intercalation has successfully taken place and that the heteroatoms (S, O) are connected to the graphene‐like structure by covalent bonds. The catalysts with 1 M H2SO4 showed superior HER performance compared to bare CF.
Symptoms and health‐related quality of life 5 years after catheter ablation of atrial fibrillation
Authors: Walfridsson Ulla , Hassel Jönsson Anders , Karlsson Lars O. , Liuba Ioan , Almroth Henrik , Sandgren Emma , Walfridsson Håkan , Charitakis Emmanouil 
Published: December 2021

AbstractObjectivesTo investigate the effect of catheter ablation (CA) on symptoms and health‐related quality of life (HRQoL) after 5 years, and analyze predictors of recurrence of symptoms.BackgroundThe primary indication for CA of atrial fibrillation (AF) is to reduce symptoms and improve HRQoL where long‐term follow‐up are sparse.MethodsIn this observational, long‐term, single‐center study, patients were recruited from Linköping University Hospital, Sweden. They were aged ≥18 years and had been referred for CA from November 2011 until June 2019. Arrhythmia‐specific symptoms and HRQoL were assessed by patient‐reported outcome measures (PROMs) with the Arrhythmia‐Specific questionnaire in Tachycardia and Arrhythmia (ASTA).ResultsIn the study were 1521 patients, 69% men, mean age 62 years. At baseline, 87% of the patients and at the 5‐year follow‐up 80% of those eligible filled out the ASTA questionnaire. At follow‐up, 50% reported freedom from symptoms, 18% had >50% symptom reduction, 14% had a minor reduction, while 18% reported no effect or a worsening of symptoms. Factors predicting symptoms were female gender (hazard ratio [HR]: 1.8; 1.2–2.8), body mass index ≥ 35 (HR: 3.9; 1.6–9.8), and ischemic heart disease (IHD) (HR: 2.6; 1.2–5.9). After 5 years, breathlessness during activity, weakness/fatigue, and tiredness were still the most common symptoms; regarding HRQoL they were impaired physical ability and deteriorated life situation.Conclusions and Clinical ImplicationsThis clinical cohort of patients with AF evaluated through PROMs showed that CA had long‐lasting effects on symptoms and HRQoL and that the use of PROMs in clinical routines was feasible. Factors predicting symptoms after CA were female gender, IHD, and obesity, an important reminder to encourage lifestyle management.