bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Clinical Efficacy and Urodynamic Changes Using Single-incision Slings (MiniArc® vs. Solyx™) for the Treatment of Female Stress Urinary Incontinence
Authors: Chiang Fook Chin , Sun Ryan , Chang Yu-Jun , Li Yi-Ing , Sun Mou-Jong 
Published: November 2021

Objective:
To compare the clinical efficacy and urodynamic parameter changes between the MiniArc and the Solyx sling for the treatment of female urodynamic stress incontinence (USI).

Materials and Methods:
One-hundred and thirty (MiniArc n = 79, BS-Solyx n = 51) patients were included in this study. Cough stress test (ST), pad test (PT), Incontinence Impact short form Questionnaire (IIQ-7), Urogenital Distress Inventory six-item questionnaire (UDI-6), Sexual Questionnaire-Short Form (PIS-Q), and urodynamic parametric changes were assessed to determine objective and subjective outcomes following the procedure. Objective cure was defined as negative ST and PT <2 g and subjective cure was defined as “No” to the answer of UDI-6 Question #3. Predictors of surgical failure were also determined.

Results:
All Solyx users, as opposed to 91.1% of MiniArc patients, obtained objective cure at postoperative 3 months (P = 0.042). No significant difference in subjective cure rates (93.7% vs. 90.2% at 3-months (P = 0.513); 89.9% vs. 80.4% at 1 year for Solyx and MiniArc patients, respectively (P = 0.126)) and improvement scores in UDI-6 and IIQ-7 were observed. The Solyx group incurred more de novo urgency (17.6% vs. 6.3% at 3 months (P = 0.042); 23.5% vs. 7.6% at 1 year (P = 0.01)). Both procedures yielded significant decrements in maximal urethral closure pressure (P < 0.001) and average flow rate (P = 0.015). The preoperative PT and sling type were strong predictors of surgical failure, where the Solyx tape reported lower odds (odds ratio = 0.174, P = 0.02) compared to the MiniArc sling.

Conclusion:
Single-incision mini-slings are safe and effective treatment for female USI. The Solyx SIS demonstrated superiority over the MiniArc in this study based on its higher objective cure rate and lower risk for surgical failure.
Comparison of Surgical Results and Postoperative Recurrence Rates by Laparoscopic Sacrocolpopexy with Other Surgical Procedures for Managing Pelvic Organ Prolapse
Authors: Kotani Yasushi , Murakamsi Kosuke , Kai Sayaka , Yahata Tamaki , Kanto Akiko , Matsumura Noriomi 
Published: November 2021

Objectives:
Pelvic organ prolapse (POP) is relatively high for a gynecologic disease. Laparoscopic sacrocolpopexy (LSC) is currently the main surgical option for managing POP. The priority of the surgical treatment is preventing recurrence after the surgery. We presented the surgical outcome and recurrence rate of LSC and compared the data of LSC with that of other surgical procedures for managing POP to examine the effectiveness of LSC over other them.

Materials and Methods:
We compared the results of 138 cases of LSC with other conventional procedures, namely 30 cases of total vaginal hysterectomy (TVH) combined with colporrhaphy anterior and posterior, 66 cases of the Manchester operation, and 68 cases of colpocleisis. We compared the age, body mass index, operative time, blood loss volume, postoperative hospital stay duration, rate of complications, recurrence rate, reoperation rate, and the cumulative recurrence rate after 10 years.

Results:
The complication rate of LSC, TVH, the Manchester operation, and colpocleisis was 2.2%, 3.3%, 3.0%, and 4.4%; the recurrence rate 2.8%, 3.5%, 4.5%, and 8.7%; and the cumulative recurrence rate after 10 years 3.7%, 4.6%, 8.8%, and 18.2%. There was no significant difference between LSC and the other three groups.

Conclusion:
LSC seems to be an effective surgical option that requires a higher skill level than other surgical methods and has a longer operative time, lesser operative invasion, and a lower long-term recurrence rate. We will actively recommend LSC to those when appropriate.
Salivary Proteome Profile of Women during Fertile Phase of Menstrual Cycle as Characterized by Mass Spectrometry
Authors: Saibaba Ganesan , Rajesh Durairaj , Muthukumar Subramanian , Sathiyanarayanan Ganesan , Aarthy Archunan Priya , Archunan Govindaraju 
Published: November 2021

Objectives:
Ovulation is such a critical physiological process that its noninvasive detection based on salivary constituents has several advantages in humans. Hence, the present study is proposed to identify the ovulatory-specific proteins in saliva in order to detect ovulation phase.

Materials and Methods:
Samples were collected from women volunteers. The procedure adopted was approved by the Institutional Human Ethical Committee (DM/2014/101/38), Bharathidasan University. The saliva samples were collected from thirty healthy female volunteers, with a prior written consent. One-way analysis of variance was used to calculate protein concentration and band intensity using SPSS 16 software (SPSS Inc., Cary, NC, USA). The salivary protein expression pattern during different phases of menstrual cycle was analyzed using gel-based high resolution-liquid chromatography-mass spectrometry/mass spectrometry and matrix-assisted laser desorption ionization-time of flight/time of flight. Further, bioinformatics tools were adopted to annotate the proteins identified at various phases of menstrual cycle.

Results:
As many as 530 proteins showed up in the saliva during ovulatory phase, whereas there were only 251 proteins identified during postovulatory phase. The functional annotation of salivary proteins revealed that the proteins got assigned to the class of “extracellular proteins” which are concerned with regulatory functions. The 16 unique and/or differentially expressed protein spots appeared during ovulatory phase, among which Cystatin-S, Prolactin-inducible protein, Cystatin-A, Cystatin-SN, BPI fold-containing family A member 2, Alpha-tubulin N-acetyltransferase 1, Carbonic anhydrase-6, Protein LEG1 homolog, Hemoglobin subunit beta, and Pancreatic alpha-amylase were identified.

Conclusion:
Total salivary proteome profile has been listed with respect to various phases of menstrual cycle. Among the protein listed, Cystatin-S offers a biomarker protein and/or indicator of ovulatory phase. However, extensive validation is required before arriving to a candidate bio-marker protein.
Step-wise Technical Description of Performing Ureteric Tunnel Dissection in Laparoscopic Radical Hysterectomy
Authors: Limbachiya Dipak , Kumari Rashmi 
Published: November 2021

Objectives:
Technical description of performing ureteric tunnel dissection in laparoscopic radical hysterectomy (LRH) surgery.

Materials and Methods:
This is a retrospective analysis. A total of 91 patients of the International Federation of Gynaecology and Obstetrics Stage IA2, IB1, and IB2 of cervical cancer were operated by the same surgeon between January 2015 and December 2019 were analyzed.

Results:
The median time for one side ureteric tunnel dissection was 3 min 15 s (range 2 min 35 s– 6 min 18 s). None of the cases were converted to laparotomy. The patients' median hospital stay was 2 days (range 1–4 days). There were no short-term or long-term complications related to ureteric tunnel dissection.

Conclusion:
This analysis explains the descriptive methodology of operative technique, especially for ureteric tunnel dissection in LRH. This technique is easily reproducible and replicable, with chances of marginal or negligible complication rates.
Comparative effectiveness and tolerability of targeted agents combined with chemotherapy in patients with HER2-positive gastroesophageal cancer
Authors: Yan Yin-Hong , Lei Xiao-Yi , Hu Wei-Ping 
Published: November 2021

Background:
Gastric cancer (GC) or gastroesophageal junction (GEJ) cancer with HER2 overexpression is highly invasive, with a poor prognosis. With the development of new targeted agents, which agents have ideal therapeutic effects must be determined. This network meta-analysis analyzed the effectiveness and tolerability of targeted agents combined with chemotherapy in HER2-positive GC/GEJ cancer.

Methods:
Public databases were searched from the date of inception to October 22, 2020. Randomized controlled trials (RCTs) on targeted agent-related regimens for HER2-positive advanced GC or GEJ cancer were included. Subgroup analyses based on publication language, first-line treatment, second/third-line treatment, and HER2 staining intensity were performed.

Results:
In total, 13 articles were included. The trastuzumabderuxtecan (TraD) and pertuzumab plus trastuzumab and chemotherapy (PerTraChemo) regimens were considered to have high effectiveness but low tolerability. In the subgroup analysis, PerTraChemo still had high effectiveness with low tolerability as the first-line therapy. As the second- or third-line therapy, TraD and lapatinib plus chemotherapy (LapChemo) had high effectiveness and moderate tolerability. In terms of overall survival (OS) time, PerTraChemo had a relative advantage in the immunohistochemistry (IHC) 2+/in situ hybridization (ISH)+ population, whereas TraD, PerTraChemo, and trastuzumab plus chemotherapy (TraChemo) had a relative advantage in the IHC3+ population.

Conclusion:
TraD had relative advantages as the second- or third-line therapy and in the IHC3 + population. PerTraChemo is a potential first-line therapy, but it requires further confirmation because the JACOB phase III clinical trial failed to confirm the superiority of PerTraChemo over TraChemo with regard to OS.
The prevalence of irritable bowel syndrome among Saudi population in Riyadh by use of Rome IV criteria and self-reported dietary restriction
Authors: Amin Hussein S. , Irfan Farhana , Karim Syed I. , Almeshari Saif M. , Aldosari Khaled A. , Alzahrani Abdullah M. , Almogbel Adnan T. , Alfouzan Saad M. , Alsaif Anas A. 
Published: November 2021

Background:
Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal disorder. Diet may play a role in triggering the symptoms. We aimed to measure the prevalence of IBS and its types, and its association with food restrictions among the Saudi population, using the Rome IV criteria.

Methods:
A cross-sectional study was conducted in the outpatient clinics of three major hospitals in Riyadh in conjunction with an electronic survey which was shared on social media. A total of 1,319 subjects (706 males and 613 females) completed a questionnaire of four domains (sociodemography, Rome IV, food restriction, and herbs) between Nov 2019 and February 2020. Convenience sampling was used.

Results:
IBS was diagnosed in 104 subjects (7.9%) and, of these, 52% were IBS-M (mixed) type. The prevalence was higher in women than in men (4.9% vs. 3.0%; P = 0.006). A significant association was found between the presence of IBS symptoms and low income (P = 0.010), and not working (P < 0.0001). Most of the IBS patients showed food restriction related to milk (P < 0.0001) and legumes (P = 0.0029), besides other types of food and drinks.

Conclusions:
IBS is less common among the Saudi population. A female gender, low family income, and working status, have the highest association with IBS. The foods most often restricted were legumes and milk. Future community studies may present an opportunity to relate with cultural differences and food preferences.
Urbain anthropocène
Authors: Mirza Vincent 
Published: November 2021

La notion d’urbain anthropocène se constitue à la confluence de deux transformations majeures des mondes contemporains en mettant l’accent sur les relations entre la crise environnementale et les enjeux urbains du XXIème siècle. L’urbain anthropocène constitue donc un cadre d’intelligibilité afin de réfléchir au lien entre l’urbanisation accélérée de la planète et la crise climatique qui remettent en cause l’habitabilité de la terre.
Prva Jugoslavija in »njena« diaspora v Braziliji
Authors: Zobec Miha 
Published: November 2021

Avtor se v prispevku ukvarja z jugoslovansko diasporo v Braziliji v obdobju med vojnama. Jugoslovanska diaspora je bila kot rezultat skupnih slovenskih in hrvaških prizadevanj usklajena s težnjami prve Jugoslavije po društvenem organiziranju na jugoslovanski osnovi, vendarle pa so bile osnove povezovanja južnoslovanskih priseljencev v Braziliji prisotne že pred prvo svetovno vojno. Jugoslovanska diaspora v Braziliji je bila zelo krhka, njeni odnosi z »domovino« pa površinski. K temu sta botrovala pomanjkanje zanimanja Jugoslavije za vzdrževanje trdnih odnosov s »svojo« skupnostjo v Braziliji kot tudi brazilska politika nacionalizacije priseljencev. Odsotnost jugoslovanskih prizadevanj so v skrbi za skupnost skušali nadomestiti izseljenski aktivisti, a so njihove akcije pogosto vodile k še večji fragmentaciji skupnosti. Avtor pozornost posveča tudi diaspori izseljencev iz Julijske krajine, katere del se je identificiral z jugoslovansko diasporo, del pa je deloval samostojno.
HUBUNGAN ASUPAN ENERGI DAN PROTEIN DENGAN STATUS GIZI SANTRI DI PESANTREN NURUL FALAH MEULABOH TAHUN 2019
Authors: Fakri Saiful , Jananda Ita 
Published: November 2021

Kebutuhan asupan remaja di pondok pesantren cendreung rendah. Hal ini karena keterbatasan makanan yang disediakan di pesantren. Karena keterbatasan serta aktifitas remaja dipesanten lebih meningkat, kebutuhan zat gizi juga meningkat dari anak sekolah biasa. Ini dibuktikan berdasarkan data Riskesdes (2013) menyatakan status gizi remaja umur 16-18 tahun mengalami peningkatan dengan prevalensi sangat kurus sebesar 1,9%, remaja kurus 7,5%, dan gemuk 7,3%. Untuk mengetahui Hubungan Asupan Energi Dan Protein Dengan Status Gizi Santri Di Pesantren Nurul Falah Meulaboh Tahun 2019. Jenis penelitian ini adalah Deskriptif Analistik dengan menggunakan rancangan cross sectional. Sasaran penelitian ini adalah santri telah memiliki umur 12-15 tahun sebanyak 30 santri yang mondok Pesantren Nurul Falah Meulaboh.. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah secara purposive sampling.
Hasil uji statistik menggunakan chi square pada derajat kepercayaan 95% menunjukkan tidak terdapatnya hubungan yang signifikan antara pengetahuan ibu tentang zat gizi dengan status gizi balita yaitu dengan nilai (p>0,05). Tidak terdapat hubungan asupan energi dan asupan protein dengan status gizi pada santri di Pesantren Nurul Falah Meulaboh p = 0,068. Diharapkan melalui penelitian ini dapat menyusun menu makanan yang seimbang dan cukup untuk meningkatkan asupan energi dan asupan protein yang bervariasi bagi remaja di pesantren.
MENINGKATKAN HASIL BELAJAR TENTANG PENGURANGAN BILANGAN BULAT DENGAN MENGGUNAKAN MEDIA BALOK GARIS BILANGAN PADA SISWA KELAS V SD NEGERI 1 TELUK BETUNG
Authors: Mayang Alia 
Published: November 2021

Penelitian ini dilatarbelakangi oleh kesulitan siswa dalam menerima materi yang masih abstrak dan situasi pembelajaran yang kurang menarik, belajar yang membosankan, siswa terlihat kurang antusias mengikuti pembelajaran dan mematikan kreativitas siswa yang berdampak pada hasil belajar yang kurang optimal. Hal ini disebabkan oleh beberapa faktor salah satunya yaitu karena siswa masih berada dalam tahapan operasi konkret, penyajian materi yang kurang melibatkan intelektual, emosional, dan fisik, dalam kegiatan belajar dan pembelajaran lebih banyak berfokus pada penguasaan atas isi buku teks dan minimnya penggunaan media dan alat peraga, pelaksanaan pembelajaran masih monoton dan siswa tidak terlibat secara aktif serta minimnya bimbingan guru dalam mengatasi kesulitan siswa.Berdasarkan permasalahan tersebut, maka tujuan penelitian yang hendak dicapai adalah untuk meningkatkan Hasil Belajar tentang pengurangan bilangan bulat dengan menggunakan media balok garis bilangan pada siswa kelas V SD Negeri 1 Teluk Betung Kecamatan Karau Kuala.
Subjek penelitian ini adalah Siswa Kelas V SD Negeri 1 Teluk Betung yang berjumlah 15 orang.Pengumpulan data dilakukan melalui observasi dan tes sedangkan analisis data digunakan analisis deskriftif kuantitatif dan kualitatif. Hasil penelitian menunjukan bahwa : 1) Hasil belajar siswa diketahui bahwa rata-rata kelas untuk pertemuan pertama adalah 8,53 diatas indikator ketuntasan belajar dengan ketuntasan klasikal sebanyak 13 orang (86,66%) dengan perolehan nilai berkisar antara 6 sampai 10 dan untuk siklus 2 naik mernjadi 9,20 diatas indikator ketuntasan belajar dengan ketuntasan klasikal sebanyak 15 orang (100%) dengan perolehan nilai berkisar antara 8 sampai 10, 2) Peningkatan aktivitas siswa dalam kelompok pada siklus 1 hanya 7,74 meningkat menjadi7,97 di siklus 2. Kesimpulannya adalah penggunaan Media balok garis bilangan pada pengurangan bilangan bulat dapat meningkatkan hasil belajar siswa kelas V SD Negeri 1 Teluk Betung Kecamatan Karau Kuala Kabupaten Barito Selatan.
PENERAPAN MODEL PEMBELAJARAN COOPERATIVE LEARNING TIPE JIGSAW DALAM MENINGKATKAN MINAT DAN HASIL BELAJAR SISWA KELAS IX F SMP N 1 CANGKUANG, KABUPATEN BANDUNG
Authors: Drajat  
Published: November 2021

Metode Jigsaw pada hakekatnya ialah sebuah model pembelajaran yang diutamakan kepada siswa, karena Peran guru sangatlah penting sebagai fasilitator. Tujuan dengan menggunakan metode ini yaitu untuk mengembangkan kerja sama tim, dan keterampilan belajar serta penguasaan pengetahuan yang mendalam secara pendidikan dengan ketidak mungkinan diperoleh siswa apabila dipelajari secara individual. Metode Jigsaw ini cocok dalam meningkatkan tujuan dan pencapaian pengajar dalam kontribusi terhadap pemahaman siswa. Sehingga siswa dapat melakukan pembelajaran dan sesekali dapat mengajarkannya kepada rekan –rekan sesama kelompok. Tidak selamanya di dalam sebuah proses ini, berjalan dengan lancar. Karena tedapat proses penghambatan yang muncul secara seketika dengan seringnya terjadi ketidak terbiasaan siswa terhadap model ini. Pengajar maupun peserta didik masih mengalami dengan terbiasanya menggunakan metode konvesional, diantaranya dengan memberikan materi secara satu arah. Adapun penghambat yang sering terjadi yaitu dengan kekurangannya waktu yang mengakibatkan proses ini menjadi lebih lama dari biasanya, sementara itu waktu yang dilaksanakan harus menyesuaikan dengan beban kurikulum yang disetujui. Bagi guru dalam memperhatikan metode ini harus lebih banyak memerlukan kemampuan lebih untuk menangani situasi dan penanganan yang berbeda. Pada Penelitian Tindakan Kelas (PTK) yang penulis lakukan ini ternyata terbukti bermanfaat untuk menjawab pertanyaan; Apakah melalui model pembelajaran cooperative learning tipe Jigsaw dapat meningkatkan hasil belajar siswa kelas IX F SMP Negeri 1 Cangkuang, Kabupaten Bandung pada materi Barisan dan Deret? Bagaimanakah minat belajar siswa kelas IX F SMP Negeri 1 Cangkuang, Kabupaten Bandung di dalam diskusi kelompok tentang materi Barisan dan Deret melalui model pembelajaran cooperative learning tipe Jigsaw? Ternyata hasilnya memuaskan.
KONFLIK INTERNAL ANTARA PEMERINTAH INDONESIA DENGAN GERAKAN SEPARATIS DI PAPUA
Authors: Putri Mardiani Indah , Anisah Ismi , Hasibuan Marlina , Fadilah Nur 
Published: November 2021

Tujuan dari artikel ini adalah untuk mengetahui Propaganda Gerakan Papua Merdeka yang dilaksanakan oleh Organisasi Papua Merdeka (OPM) melalui media cetak dan online menjadikan pesan-pesan OPM menyebar dengan cepat dan luas ke tengah-tengah masyarakat global, sehingga OPM cenderung mendapat perhatian dan dukungan dari dunia Internasional. Setelah terjadinya penyerangan kepada warga sipil oleh salah satu faksi OPM di Kabupaten Nduga, Papua, berbagai media, salah satunya portal utama media online OPM, freewestpapua.org, memberitakan kasus tersebut sesuai dengan perspektif masing-masing. Oleh karena gerakan OPM bertentangan dengan prinsip Negara Kesatuan Republik Indonesia, itu menjadi penting untuk kita mengetahui bagaimana OPM mencitrakan Pemerintah Indonesia dalam berita mengenai kasus tersebut. Setelah dilakukan analisis wacana kritis model Van Dijk terhadap teks berita yang dipilih secara purposif dari situs web freewestpapua.org, disimpulkan bahwa baik dalam struktur teks Makro, Superstruktur, maupun Mikro, meskipun pelaku penyerangan warga sipil adalah OPM sendiri, dan korbannya bukan orang Papua, situs propaganda online OPM, tetap mencitrakan Indonesia sebagai penjajah yang sadis, brutal, licik, dan biadab. Metode penelitian yang digunakan penulis adalah metode penelitian kualitatif yang dilandaskan oleh Teori dan penjelasan. Guna dari dipilihnya metode ini adalah untuk menilai terhadap bagaimana kondisi obyek yang alami.
Tourists’ characteristics in relation to expectations, satisfaction and loyalty in hotel industry
Authors: Santos Roldán Luna , Palacios Florencio Beatriz , Bolcha Peter 
Published: November 2021

Objective: This paper makes an effort in combining the hotel subsector with a specific geographic location and with three determined constructs.
Methods: This article uses a unique individual level dataset collected in Spain hotels and attempts to shed more light on three phases of consumer evaluation: expectations, satisfaction and loyalty. In order to relate the evaluation scores in these areas to sociodemographic characteristics of the consumers, we employ regression analysis.
Results: The results show that all dependent variables in hand are related to explanatory variables; often in directions assumed by theory or previous empirical studies. Specifically, we find that age, economic status and country of origin are statistically significantly related to consumer evaluation. One of the novelties of our study is inclusion of “exceeded expectations” variable that intends to measure positive or negative surprise with the service.
Conclusion: The knowledge of the existence of incidences of demographic variables on satisfaction, loyalty and expectations could not only, but should, lead to the formulation and implementation of differentiated strategies, segmented according to groups of individuals, focused on improving these indicators, adapting services to the demographic characteristics of the clients.
Synthesis and Characterization of Pectin Beads for the Smart Delivery of Agrochemicals
Authors: Pavithran P. , Marimuthu S. , Chinnamuthu C. R. , Lakshmanan A. , Bharathi C. , Kadhiravan S. 
Published: November 2021

Aim: The study was conducted to design pectin beads for achieving slow release of agrochemicals in wetlands via ion gelation method.
Place and Duration of the Study: The laboratory experiment was carried out at the Department of Nano Science & Technology, Tamil Nadu Agricultural University, Tamil Nadu during March-July 2021.
Methodology: Pectin beads were synthesized varying the concentrations of pectin (4, 6, 8, and 10 per cent) and calcium chloride (CaCl2) concentrations (0.5, 1, and 2 per cent). Calcium pectinate beads of different combinations were synthesized via ion gelation method. Calcium pectinate beads were characterized based on the recovery yield of beads, while surface characterization was done through Scanning electron microscope (SEM) and optical microscope to understand the topography of beads and assess the size of the beads respectively. Pore volume and surface area were also studied using BET (Brunauer-Emmett-Teller) analyzer.
Results: The yield of calcium pectinate beads were higher while using the concentration of pectin @ 4 per cent and CaCl2 @ 2 per cent as cross-linking agent. The spherical and smooth surface of beads was achieved with the concentrations of 6 and 2 per cent pectin and CaCl2 respectively, while beads were flat and smooth with concentration of pectin @ 4 per cent. Similarly, complete solubility of pectin was not achieved with concentrations of 8 and 10 per cent. BET results of beads showed that beads are non-porous in nature.
Conclusion: Pectin and CaCl2 concentrations @ 6 and 2 per cent respectively were found to be ideal for the delivery of agrochemical based on the yield and surface morphology.