bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of DSC (differential scanning calorimetry) thermograms of milk fat
Authors: Shamilova Maltam , Hajiyeva Sevinj 
Published: November 2021

The object of current research is the oxidation and melting properties of milk fat samples in different heating rates. One of the most problematic issues is the evaluation dependence of temperature and oxidation time regarding to heat flow, and the estimation of attitude of enthalpy values to heating rates. In order to gain a comprehensive assessment of oxidation and melting properties of milk fat samples on differential scanning calorimeter in various heating rates, it is necessary to conduct experimental studies.
The analysis was performed using the dynamic option of the differential scanning calorimetry (DSC) with the following sample heating rates: 2.5, 4, 5, 7.5, 10, 12.5, 15 °C⋅min–1. Analyses were performed on 14 samples of milk fat, thus, for each heating rate were intended to two milk fat samples.
As a result of the analysis, in the proper heating rates increased, it was found, that the oxidation properties of milk fat depend on the heating rates on DSC examination. In the thermal DSC analysis, the start temperature (Ts) (inlet), the onset temperature (Ton), and the maximum heat flow-peak temperatures (Tp) of oxidation were rising gradually. All the value of oxidation increased gradually with increasing heating rate, only in the Tend values were chainable among all heating rates. However, the oxidation time of milk fat is inversely proportional to the various heating rates in DSC. The oxidation enthalpy was calculated according to the heating rates too. The masses of the samples differ from each other, albeit slightly, which the individuality in the value of enthalpy could be explained through this ratio and duration of exothermic. The melting point considers the important indicator to explain the purity of samples. Melting curves of extracted milk fat samples on DSC were characterized by endothermic behavior and observed with the mild peaks, the first and the second distinct peaks due to the low-melting triacylglycerols (with high unsaturated fatty acids content) and high-melting fats, which present in milk fat.
In concluded results, the characteristics of DSC oxidation curves are melting point due to the chemical structure of the fatty acids which milk fat samples contain.
Removal of chromium (VI) ions from aqueous solutions
Authors: Obushenko Tetiana , Tolstopalova Nataliia , Chyrieva Mariia 
Published: November 2021

The object of the research is the flotoextraction of chromium (VI) ions from model and real waste waters. Hexavalent chromium compounds pose a serious hazard to surface and ground waters and can have mutagenic and carcinogenic effects on living organisms. The study of the process of flotoextraction as a method of purifying waste water from heavy metals using the example of chromium (VI) ions is an important task. The paper considers flotoextraction of chromium (VI) ions using a cationic surfactant – hexadecylpyridinium chloride and butyl alcohol as the organic phase. The dependences of the process efficiency on the presence of a cationic surfactant, the flotoextraction time, the type of organic extractant, the nature of the collector and the surfactant: Cr molar ratio, the initial concentration of pollutants, and the pH of the initial solution were obtained. Certain rational conditions for flotation allow removing 98–99.6 % of pollutants. The method was tested on real wastewater.
The importance of this study is emphasized by the fact that flotoextraction has a number of features and advantages. In particular, the possibility of multiple concentration of pollutant ions in small volumes of an organic solvent and the possibility of its further regeneration. In this case, a much smaller amount of an organic solvent is used and the process is not limited by the distribution constant (compared to the extraction method). Flotoextraction is also characterized by the absence of foam (compared to the flotation method) and the absence of large amounts of wet sludge (compared to the reagent method). The proposed method provides a sufficient level of chromium ions removal from wastewater, and can also be used in systems for local wastewater treatment with the subsequent return of water to the technological process. This will ensure a reduction in costs for the consumption of water resources, discharge of wastewater into water bodies, and also limit the ingress of harmful substances into the environment.
Assessement of neonatal sepsis and associated factors among neonates admited neonatal intensive care unit in selected public hospitals in Somali Region, Ethiopia
Authors: NUR Abdikani , OSMAN Mohamed 
Published: November 2021

Objectives: To assess neonatal sepsis and associated factors among neonates admitted neonatal intensive care unit in selected public hospitals in Somali region, Ethiopia. Methods: Institution based cross sectional study design was conducted in selected public hospitals. Data was collected using structured questionnaire adopted from other literature, entered into Epi-data version 3.1 and then was exported to SPSS version 23 for analysis. Frequency was used for descriptive analysis. Bivariate analysis was used to determine the association between different risk factors and the outcome variable. Those variables which have significant association at 5% significance level and fulfilling the minimum requirement of 0.2 level of significance with neonatal sepsis was entered for further analysis to multivariate analysis, significance was taken at α = &lt; 0.05. Results: The overall prevalence of this study was 42.9% CI = (38.4-47.8) and associated factors was age of the neonate AOR = 0.085 (CI = 0.01, 0.73), Residence shown AOR = 2.567 (CI = 1.01, 6.5) Gestational age AOR = 1.869 (CI = 1.05, 3.31), Meconium stained Amniotic fluid AOR = 2.718 (CI = 1.89, 6.74), Antenatal care AOR = 8.933 (CI = 4.9, 15.9), and Mechanical ventilation after birth OR = 3.376 (CI = 1.65, 6.88). Conclusions: The present study found that the overall prevalence of neonatal sepsis in selected hospitals was 42.9%. The study identified, Age of the neonate, Residence, Gestational age, Meconium stained amniotic fluid. Antenatal care, Mechanical ventilation after birth. The findings underscore the importance of routine assessment and close monitoring of neonates. It is therefore recommended to have more skilled health personnel and advanced equipment while providing maternal and new-born health care services.
ASSESSMENT OF THE ENVIRONMENTAL SAFETY FACTORS OF PLAY-GROUNDS USING THE RANK CORRELATION METHOD
Authors: Stadnik V. 
Published: November 2021

The process of rapid development in modern cities has led to a significant number of playgrounds being located in confined areas, near roads with heavy vehicle traffic (including tram tracks), next to short-term parking spaces and refuse containers. Particular attention is paid to unauthorised parking which is caused by a lack of designated parking spaces. In addition, in residential areas of modern megacities there is a lot of infill development, which is an additional source of noise and dust. Thus, a significant number of playgrounds are located in areas with excessive anthropogenic load.
The materials presented in the article describe the current condition of playgrounds in most big cities of Ukraine. Particular importance is attached to the factors which are connected with vehicle traffic, for example noise pollution, air dustiness and pollutant emissions.
At the first stage, a list of factors affecting the environmental safety of children's playgrounds in urbanised areas was compiled and analysed.
The next stage involves the development of a questionnaire and the direct assessment of the influencing factors by the experts involved. The article considers the factors that are rarely considered in the study of the impact of individual anthropogenic factors of the environment on public health, however, in modern conditions they cannot be neglected.
The final stage consists of data processing and formation of conclusions. Using the method of rank correlation, the main factors of influence on the objects of research are identified.
The results of the research stated in the article can be used in further study of the subject and in the development of methods to eliminate the influence of the most significant factors affecting the ecological safety of children's playgrounds.
Contamination by Hazardous Elements in Low – Priced Children’s Plastic Toys Bought on the local Markets of Karachi, Pakistan
Authors: Gul Dur-e-Shahwar , Gul Anam , Tanoli Asad Khan , Ahmed Tehseen , Ahmed Mubashir 
Published: November 2021

Abstract
Children’s plastics toys maybe contain toxic metals to which infants and young children can be orally exposed and may pose acute or chronic adverse health effects. The objectives of this research were to evaluate the total metal concentrations (TMCs) of Pb, Cd, Cr, Ni, Zn, Cu, and Mn in children’s plastic Toys Bought in the local markets of Karachi, Pakistan, and compared TMCs to different regulatory limits. Total 44 children’s plastic toys sourced in the Karachi local markets had analyzed by an atomic absorption spectrophotometer for heavy metals contaminations. These toy samples had divided into two groups; Plastic toys (DCT) and Plastic toys with paints or coatings (DPCT). For plastic toys, 83% (19) of samples had TMCs that exceeded European Union (EU) toy safety regulation limits for Pb, and 65% (15) of samples that exceeded for Cd. For plastic toys with paints or coating, 43% (9) of samples had TMCs that exceeded EU migration limits for Pb and 24% (5) for Cd. More than 20 samples exceeded the United States Consumer Product Safety Commission (U.S. CPSC), Canadian, and Bureau of Indian Standards (BIS) toy safety regulation limits. In toys samples (n = 44) very high TMCs of Pb (64%), Cd (45%), Cr(5%), and Ni (2%) were observed. Zn, Cu, and Mn TMCs were also existing but below the Regulation limits. The Contamination levels of Pb, Cd, Cr, and Ni and smaller extent of Zn, Cu, and Mn still pose health issues in children and may cause serious problems in their health.
Liquid-Liquid Nanogenerator basing on Aqueous-Aqueous Interface
Authors: Jiang Long-Long , Lu Ye , Yu Yang , Wang Dehua , Hu Han , Liu Yang , Yu Jing , Zhang Jun , Ma Qingming , Wang Xiaoxiong 
Published: November 2021

Abstract
Solid nanogenerators often have a limited charge transfer due to the low contact area. Compared with solid-solid or solid-liquid nanogenerators, liquid-liquid nanogenerators can effectively increase the transferred charge. Limited by the fluidity of the liquid, the precise manipulation of the liquid morphology remains a challenge. In this work, using the surface tension of the droplet to fix the shape, we designed a new liquid-liquid triboelectric nanogenerator by using the immiscible aqueous-aqueous interface, achieving the contact surface charge transfer of 129 nC of a single droplet. This liquid-liquid nanogenerator has been proven to be applicable in humid environments, and the two-phase materials have good biocompatibility and can be used as a good carrier for drugs. Therefore, this nanogenerator is useful for future design of implantable devices and the design of a new type of bionic fully self-powered system has great potential. Meanwhile, such design established the foundation of aqueous electronics and more creation can be achieved by using this route.
Early Biomarkers Associated with P53 Signaling for Acute Radiation Injury
Authors: Li Weihong , Zhou Shixiang , Jia Meng , Li Xiaoxin , Li Lin , Wang Qi , Qi Zhenhua , Zhou Pingkun , Li Yaqiong , Wang Zhidong 
Published: November 2021

Abstract
Background: Rapid and accurate high-throughput estimation of radiation dose aims to help medical rescue in nuclear radiation accident. However, current methods of dose estimation are still lacking of speedy or accuracy. P53 signaling pathway plays an important role in DNA damage repair and cell apoptosis induced by ionizing radiation. The changes of radiation-induced P53 related genes in the early stage of ionizing radiation should compensate for the deficiency of lymphocyte decline and γ-H2AX analysis as novel biomarkers of radiation damage. Methods: Bioinformatic analysis was performed on previous data to find candidate genes from human peripheral blood irradiated in vitro. The radiation sensitivity and baseline levels of candidate genes were verified. The approximate threshold for guiding medical treatment was estimated for each gene, and four genes were combined to construct an effectively early dose estimation model of radiation.Results: Four p53-related genes, DDB2, AEN, TRIAP1 and TRAF4, were screened and verified their significant radiosensitivity. Their expressions were stable without gender or age difference in healthy population, but significantly up-regulated by radiation, with time specificity and dose dependence in 2h-24h after irradiation. Further studies showed these genes can be used as indicators for early medical treatment in acute radiation injury. The effective combination of the four genes could achieve a more accurate dose assessment and injury classification for large-scale wounded patients within 24 hours post exposure.Conclusions: This is the first time to investigate the potential biomarkers of ionizing radiation by systematic study. The effective combination of the four genes provides a new model for dose estimation and injury classification of a large number of exposed population in acute nuclear accidents, and also provides a new idea and method.
Systemic Immune-Inflammation Index as a Prognostic Marker of Late Recurrence in Operable Gastric Cancer: A Dual Center Study
Authors: Yekedüz Emre , Doğan İzzet , Kaya Dılşa Mızrak , Özgür İlker , Utkan Güngör , Vatansever Sezai , Demirci Salim , Akbulut Hakan , Ürün Yüksel 
Published: November 2021

Abstract
Aim
To evaluate the prognostic role of the systemic immune-inflammation index (SII) in patients with operable gastric cancer.
Methods
We assessed 354 patients with operable gastric cancer from tertiary centers in Turkey. SII was calculated by following formula: [neutrophil (cellsx109/L) x platelet (cellsx109/L)] / lymphocyte (cellsx109/L). The best cut-off value for SII was determined by using “receiver operating characteristics (ROC)” analysis. We used log-rank and Cox-regression analysis for survival analyses.
Results
One hundred twenty patients were in the late recurrence group (recurrences have developed 36 months after the surgery). SII was not a prognostic factor in the early recurrence group. However, relapse-free survival (RFS) was longer in SII-low patients than SII-high patients in the late recurrence group. In multivariable analysis, SII was the only independent prognostic factor for RFS in the late recurrence group (Hazard Ratio (HR): 5.42, 95% CI:1.18-24.82, p=0.03).
Conclusion
SII was an independent prognostic factor for RFS in GC patients with late recurrence. Late recurrence risk was higher in SII-high patients than SII-low patients. Inflammation contributes to tumor progression, invasion, and metastasis. Prolonged exposure to chronic inflammation could explain the results of this study.
Randomized Controlled Trial: Neostigmine for Intra-abdominal Hypertension in Acute Pancreatitis
Authors: He Wenhua , Chen Peng , Lei Yupeng , Xia Liang , Liu Pi , Zhu Yong , Zeng Hao , Wu Yao , Ke Huajing , Huang Xin , Cai Wenhao , Sun Xin , Huang Wei , Sutton Robert , Zhu Yin , Lu Nonghua 
Published: November 2021

Abstract
Background: Intra-abdominal hypertension (IAH) in acute pancreatitis (AP) is associated with deterioration in organ function. This trial aimed to assess the efficacy of neostigmine for IAH in patients with AP.Methods: In this single-centre, randomized trial, consenting patients with IAH within 2 weeks of AP onset received conventional treatment for 24 hours. Patients with sustained intra-abdominal pressure (IAP) ≥ 12 mmHg were randomized to receive intramuscular neostigmine (1 mg every 12 hours increased to every 8 hours or every 6 hours, depending on response) or continue conventional treatment for 7 days. The primary outcome was the change of IAP after randomization. Results: A total of 80 patients were recruited to neostigmine (n = 40) or conventional treatment (n = 40). There was no significant difference in baseline parameters. IAP levels were significantly lower in neostigmine group than conventional treatment group at 9 hour (13.8 ± 3.5 vs 15.0 ± 3.1, P = 0.038), 15 hour (13.3 ± 3.4 vs 14.7 ± 3.1, P = 0.015), and 168 hour (12.2 ± 2.7 vs 13.6 ± 3.5, P = 0.045) after randomisation. This effect was more pronounced in patients with baseline IAP ≥ 15 mmHg (all P ≤ 0.038). Stool volume was consistently higher in the neostigmine group during the 7-day period (all P < 0.05). Other secondary outcomes were not significantly different between the two groups.Conclusion: Neostigmine reduced IAP and promoted defecation in patients with AP and IAH. These results warrant a larger, placebo-controlled, double-blind phase III trial.Trial registration: Clinical Trial No: NCT02543658 (registered August /27, 2015). https://clinicaltrials.gov/ct2/show/NCT02543658
HD 74438: A tight spectroscopic quadruple as possible progenitor of sub-Chandrasekhar Type Ia supernovae
Authors: Merle Thibault , Hamers Adrian , Eck Sophie Van , Jorissen Alain , Swaelmen Mathieu Van der , Pollard Karen , Pourbaix Dimitri , Smiljanic Rodolfo , Zwitter Tomaz , Traven Gregor , Gilmore Gerard , Randich Maria Sofia , Gonneau Anaïs , Houriane Anna , Sacco Germano , Worley C. 
Published: November 2021

Abstract
Stars often form in multiple systems and may follow a complex evolution involving mass transfer and collisions, leading to mergers that are possible progenitors of Type Ia supernovae (SNe) [1, 2]. The progenitors of such explosions are still highly debated [3]. While binaries have received much attention so far, higher-order stellar systems show a wide variety of interactions especially in tight systems, like long-term gravitational effects playing a key role in triple (where they are called von Zeipel-Lidov-Kozai , [4, 5], hereafter ZLK, oscillations) and quadruple systems. Here we report on the properties of the first spectroscopic quadruple (SB4) found within a star cluster: the 2+2 hierarchical system HD 74438 [6]. Its membership in the open cluster IC 2391 makes it the youngest (43 My) SB4 discovered so far. The eccentricity of the 6 y outer period is 0.46 and the two inner orbits, with periods of 20.5 d and 4.4 d, and eccentricities of 0.36 and 0.15, are not coplanar. Using an innovative combination of ground-based high resolution spectroscopy [7, 8, 9, 10] and Gaia/Hipparcos astrometry [11, 12, 13, 14], we show that this system is undergoing secular interaction that likely pumped the eccentricity of one of the inner orbit higher than expected for the spectral types of its components. We compute the future evolution of HD 74438 by considering gravitational dynamics, stellar evolution, and binary interactions [15], and show that this system is an excellent candidate progenitor of sub-Chandrasekhar Type Ia supernova through white dwarf (WD) mergers. This specific type of SNIa better accounts for the chemical evolution of iron-peak elements in the Galaxy [16].
Diagnosis of Significant Liver Fibrosis in Patients With Chronic Hepatitis B By Using a Deep Learning-Based Data Integration Network
Authors: Liu Zhong , Wen Huiying , Zhu Ziqi , Li Qinyuan , Liu Li , Li Tianjiao , Xu Wencong , Hou Chao , Huang Bin , Li Zhiyan , Dong Changfeng , Chen Xin 
Published: November 2021

Abstract
Background and aims:
Chronic hepatitis B virus (CHB) infection remains a major global health burden and the non-invasive and accurate diagnosis of significant liver fibrosis (≥F2) in CHB patients is clinically very important. This study aimed to assess the potential of the joint use of ultrasound images of liver parenchyma, liver stiffness values, and patients’ clinical parameters in a deep learning model to improve the diagnosis of ≥F2 in CHB patients.
Methods
Of 527 CHB patients who underwent US examination, liver elastography and biopsy, 284 eligible patients were included. We developed a deep learning-based data integration network (DI-Net) to fuse the information of ultrasound images of liver parenchyma, liver stiffness values and patients’ clinical parameters for diagnosing ≥F2 in CHB patients. The performance of DI-Net was cross-validated in a main cohort (n =155) of the included patients and externally validated in an independent cohort (n = 129), with comparisons against single-source data-based models and other non-invasive methods in terms of the area under the receiver-operating-characteristic curve (AUC).
Results
DI-Net achieved an AUC of 0.943 (95% confidence interval [CI]: 0.893-0.973) in the cross-validation, and an AUC of 0.901 (95% CI: 0.834-0.945) in the external validation, which were significantly greater than those of the comparative methods (AUC ranges: 0.774-0.877 and 0.741-0.848 for cross- and external validations, respectively, Ps < 0.01).
Conclusion
The joint use of ultrasound images of liver parenchyma, liver stiffness values, and patients’ clinical parameters in a deep learning model could significantly improve the diagnosis of ≥F2 in CHB patients.
A thermodynamic origin for the Cohen-Kaplan-Nelson bound
Authors: Ramakrishna Satish 
Published: November 2021

Abstract
The Cohen-Kaplan-Nelson bound is imposed on the grounds of logical consistency (with classical General Relativity) upon local quantum field theories. This paper puts the bound into the context of a thermodynamic principle applicable to a field with a particular equation of state in an expanding universe. This is achieved without overtly appealing to either a decreasing density of states or a minimum coupling requirement, though they might still be consistent with the results described.
Short Communication: A Within- and Across-country Assessment of the Genomic Diversity and Autozygosity of South African and Eswatini Nguni Cattle
Authors: Lashmar Simon Frederick , Visser Carina , Okpeku Moses , Muchadeyi Farai Catherine , Mapholi Ntanganedzeni Olivia , Marle-Köster Esté van 
Published: November 2021

Abstract
In southern Africa, the Nguni cattle breed is classified as an indigenous and transboundary animal genetic resource that manifests unique adaptation abilities across distinct agroecological zones. The genetic integrity of various ecotypes is under potential threat due to both indiscriminate crossbreeding and uncontrolled inbreeding. The aim of this study was to assess the genetic diversity and autozygosity that exists both across countries (ES: eSwatini; SA: South Africa) and within-country (SA), between purebred stud animals (SA-S) and research herds (SA-R). Subsets of 96 ES, 96 SA-S and 96 SA-R genotyped for 40 930 common SNPs were used to study inbreeding, runs of homozygosity (ROH) and heterozygosity (ROHet) profiles as well as population structure. The highest proportion (0.513) of the 3 595 ROH was &lt;4Mb in length, while the majority (0.560) of the 4 409 ROHet segments fell within the 0.5-1Mb length category. Inbreeding coefficients indicated low inbreeding (FROH range: 0.025 for SA-S to 0.029 for SA-R). Principal component (PCA) and population structure (K=5) analyses illustrated genomic distinctiveness between SA and ES populations, greater admixture for SA-R (mean±standard deviation proportion shared=0.631±0.353) compared to SA-S (mean±standard deviation proportion shared=0.741±0.123), and three subpopulations for ES. Overall, results illustrated that genetic distinctiveness in the Nguni resulted from both geographic isolation and exposure to different production strategies. Although no impending threat to genetic diversity was observed, further loss should be monitored to prevent endangerment of unique and beneficial indigenous resources.