bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hydrodynamic drag reduction of shear-thinning liquids in superhydrophobic textured microchannels
Authors: Gaddam Anvesh , Sharma Himani , Ahuja Ratan , Dimov Stefan , Joshi Suhas , Agrawal Amit 
Published: August 2021

AbstractSuper-hydrophobic textured surfaces reduce hydrodynamic drag in pressure-driven laminar flows in micro-channels. However, despite the wide usage of non-Newtonian liquids in microfluidic devices, the flow behaviour of such liquids was rarely examined so far in the context of friction reduction in textured super-hydrophobic micro-channels. Thus, we have investigated the influence of topologically different rough surfaces on friction reduction of shear-thinning liquids in micro-channels. First, the friction factor ratio (a ratio of friction factor on a textured surface to a plain surface) on generic surface textures, such as posts, holes, longitudinal and transverse ribs, was estimated numerically over a range of Carreau number as a function of microchannel constriction ratio, gas fraction and power-law exponent. Resembling the flow behaviour of Newtonian liquids, the longitudinal ribs and posts have exhibited significantly less flow friction than the transverse ribs and holes while the friction factor ratios of all textures has exhibited non-monotonic variation with the Carreau number. While the minima of the friction factor ratio were noticed at a constant Carreau number irrespective of the microchannel constriction ratio, the minima have shifted to a higher Carreau number with an increase in the power-law index and gas fraction. Experiments were also conducted with aqueous Xanthan Gum liquids in micro-channels. The flow enhancement (the flow rate with super-hydrophobic textures with respect to a smooth surface) exhibited a non-monotonic behaviour and attenuated with an increase in power-law index tantamount to simulations. The results will serve as a guide to design frictionless micro-channels when employing non-Newtonian liquids.
ReOpen demands as public health threat: a sociotechnical framework for understanding the stickiness of misinformation
Authors: Tripodi Francesca Bolla 
Published: August 2021

AbstractIn the absence of a national, coordinated, response to COVID-19, state and local representatives had to create and enforce individualized plans to protect their constituents. Alongside the challenge of trying to curb the virus, public health officials also had to contend with the spread of false information. This problematic content often contradicted safeguards, like masks, while promoting unverified and potentially lethal treatments. One of the most active groups denying the threat of COVID is The Reopen the States Movement. By combining qualitative content analysis with ethnographic observations of public ReOpen groups on Facebook, this paper provides a better understanding of the central narratives circulating among ReOpen members and the information they relied on to support their arguments. Grounded in notions of individualism and self-inquiry, members sought to reinterpret datasets to downplay the threat of COVID and suggest public safety workarounds. When the platform tried to flag problematic content, lack of institutional trust had members doubting the validity of the fact-checkers, highlight the tight connection between misinformation and epistemology.
A life cycle assessment of the environmental impacts of cattle feedlot finishing rations
Authors: Werth Samantha J. , Rocha Alice S. , Oltjen James W. , Kebreab Ermias , Mitloehner Frank M. 
Published: August 2021

Abstract
Purpose
A life cycle assessment was performed for the production of a total mixed ration (TMR) fed to finishing feedlot cattle in California, USA. The goal was to determine the climate change impact of the feed supply chain associated with the production of 1 kg finishing TMR (kg CO2e/kg TMR). A secondary goal was to compare the climate change impact of feed versus finished beef (kg CO2e/kg live weight).

Methods
The TMR was based on feeds commonly fed to finishing cattle in California. The Livestock Environmental Assessment and Performance Partnership (LEAP) guidelines were followed for inventory data collection. System boundaries included the production of crops and feed additives, transportation of TMR components, and compound feed production. Data were sourced from national databases and Ecoinvent™ unit process data. Three scenarios were assessed as a result of allocation at the transportation step: Scenario A (100% empty return load); Scenario B (50% empty return load): and Scenario C (0% empty return load). Energy, mass, and economic allocation, and system expansion of dried distillers grain solubles (DDGS) were assessed for sensitivity analysis. Total feedlot emission data from Stackhouse-Lawson et al. (2012) were used to compare to impacts of TMR production.

Results
Total emissions were determined to be 0.630 kg CO2e/kg TMR for Scenario A, 0.576 kg CO2e/kg TMR for Scenario B, and 0.521 kg CO2e/kg TMR for Scenario C. Corn production, transportation, and liquid premix production were primary contributors to the life cycle impacts of TMR production. Mass-based allocation of DDGS was found to have the most significant effect on overall impacts of the finishing TMR, with a 42% increase in life cycle emissions compared to other allocation methods. For Scenario A, feed used in Angus feedlot production contributed to 76% of total Angus feedlot emissions. Additionally, feed used in Holstein feedlot production contributed to 58% of total Holstein feedlot emissions.

Conclusions and recommendations
The present study demonstrates a need to better assess the feed supply chain of feedlot beef production in order to accurately identify areas that have the most significant impacts on overall emissions. This may aid in minimizing impacts associated with feed production and, by extension, beef production. The present study may also serve to inform future decisions for improvements or alterations of the LEAP guidelines.
Wer besucht Mathematikvorkurse?
Authors: Karapanos Marios , Pelz Robert 
Published: August 2021

ZusammenfassungTeilnehmer und Nicht-Teilnehmer eines Mathematikvorkurses (N = 394) an einer Fachhochschule wurden auf Unterschiede in leistungsassoziierten Persönlichkeitsmerkmalen und schulischen Vorleistungen untersucht. Eine logistische Regressionsanalyse weist auf nur marginale Unterschiede in den erfassten Merkmalen zwischen den beiden Gruppen hin. Während Nicht-Teilnehmer zwar über einen etwas besseren Schulnotendurchschnitt verfügten, berichteten Teilnehmer eine leicht höhere mathematikbezogene Selbstwirksamkeitserwartung und allgemeine Misserfolgsängstlichkeit. Persönlichkeit und Leistungspotential scheinen bei der Teilnahmeentscheidung von nachrangiger Bedeutung zu sein. Als relevant erweisen sich aber lebensweltliche Umstände wie etwa die noch fehlende Unterkunft am Studienort und Zeitmangel. Die Ergebnisse legen nahe, dass Vorkurse weder vorrangig von Studienanfängern mit schlechteren Voraussetzungen besucht werden, noch von solchen mit besonders günstigen. Die intendierte kompensatorische Wirkung können sie damit nur teilweise entfalten.
Granny-Export? The Morality of Sending People to Care Homes Abroad
Authors: de Vries Bouke 
Published: August 2021

AbstractMany higher-income countries are struggling to make decent and affordable care available to their older populations. In response, some Germans are sending their ageing relatives to relatively high-end care homes within Eastern Europe and South-East Asia where the care tends to be more comprehensive and a lot cheaper. At the same time, this practice has caused much controversy within Germany, with some commentators calling it “inhumane” and “shameful.” The aim of this article is to show that such criticisms are exaggerated. Whereas sending people to care homes in lower-income countries can be immoral, I argue that the most promising objections against it do not always apply and, to the extent that they do, do not always provide decisive reasons against sending people abroad. These objections maintain that such expatriations harm three different groups of individuals, namely the emigrants themselves; their friends and relatives; and vulnerable members of the receiving societies.
Multimodal Autoencoder Predicts fNIRS Resting State From EEG Signals
Authors: Sirpal Parikshat , Damseh Rafat , Peng Ke , Nguyen Dang Khoa , Lesage Frédéric 
Published: August 2021

AbstractIn this work, we introduce a deep learning architecture for evaluation on multimodal electroencephalographic (EEG) and functional near-infrared spectroscopy (fNIRS) recordings from 40 epileptic patients. Long short-term memory units and convolutional neural networks are integrated within a multimodal sequence-to-sequence autoencoder. The trained neural network predicts fNIRS signals from EEG, sans a priori, by hierarchically extracting deep features from EEG full spectra and specific EEG frequency bands. Results show that higher frequency EEG ranges are predictive of fNIRS signals with the gamma band inputs dominating fNIRS prediction as compared to other frequency envelopes. Seed based functional connectivity validates similar patterns between experimental fNIRS and our model’s fNIRS reconstructions. This is the first study that shows it is possible to predict brain hemodynamics (fNIRS) from encoded neural data (EEG) in the resting human epileptic brain based on power spectrum amplitude modulation of frequency oscillations in the context of specific hypotheses about how EEG frequency bands decode fNIRS signals.
B-cell activating factor BAFF as a novel alert marker for the immunological risk stratification after kidney transplantation
Authors: Schuster Antonia Margarete , Miesgang N. , Steines L. , Bach C. , Banas B. , Bergler T. 
Published: August 2021

AbstractThe B cell activating factor BAFF has gained importance in the context of kidney transplantation due to its role in B cell survival. Studies have shown that BAFF correlates with an increased incidence of antibody-mediated rejection and the development of donor-specific antibodies. In this study, we analyzed a defined cohort of kidney transplant recipients who were treated with standardized immunosuppressive regimens according to their immunological risk profile. The aim was to add BAFF as an awareness marker in the course after transplantation to consider patient’s individual immunological risk profile. Included patients were transplanted between 2016 and 2018. Baseline data, graft function, the occurrence of rejection episodes, signs of microvascular infiltration, and DSA kinetics were recorded over 3 years. BAFF levels were determined 14 d, 3 and 12 months post transplantation. Although no difference in graft function could be observed, medium-risk patients showed a clear dynamic in their BAFF levels with low levels shortly after transplantation and an increase in values of 123% over the course of 1 year. Patients with high BAFF values were more susceptible to rejection, especially antibody-mediated rejection and displayed intensified microvascular inflammation; the combination of high BAFF + DSA puts patients at risk. The changing BAFF kinetics of the medium risk group as well as the increased occurrence of rejections at high BAFF values enables BAFF to be seen as an awareness factor. To compensate the changing immunological risk, a switch from a weaker induction therapy to an intensified maintenance therapy is required.
Mutually Exclusive Expression of COL11A1 by CAFs and Tumour Cells in a Large panCancer and a Salivary Gland Carcinoma Cohort
Authors: Arolt Christoph , Hoffmann Franziska , Nachtsheim Lisa , Wolber Philipp , Guntinas-Lichius Orlando , Buettner Reinhard , von Eggeling Ferdinand , Quaas Alexander , Klußmann Jens Peter 
Published: August 2021

AbstractProcollagen 11A1 (COL11A1) is a central component of the extracellular matrix in many carcinomas, which is considered to be mainly produced by cancer associated fibroblasts (CAFs). As COL11A1 expression correlates with adverse prognosis and is implicated in chemoresistance, it is a promising putative target. For the first time, we used RNA in-situ hybridization to systematically identify the cells that produce COL11A1 in the ten most prevalent carcinoma types, lymphomas (n = 275) and corresponding normal tissue (n = 55; panCancer cohort). Moreover, as most salivary gland carcinomas (SGC) display distinct stromal architectures, we also analysed 110 SGC. The corresponding protein formation of COL11A1 was determined by MALDI-TOF–MS-Imaging. We report that colon, breast and salivary duct carcinomas are highly infiltrated by COL11A1 positive CAFs (CAFsCOL11A1) and might thus be promising candidates for antidesmoplastic or COL11A1-targeted therapies. The amount of CAFsCOL11A1 correlated significantly with tumour grade, tumour stage and nodal spread in the panCancer cohort. Significant associations between CAFsCOL11A1 and vascular invasion, perineural spread and nodal spread were observed in the SGC cohort. Also, we discovered that tumour cells of intercalated duct derived SGC and CAFs produce COL11A1 in a mutually exclusive manner. Our findings represent a novel mode of extracellular matrix production in carcinomas and could be highly relevant in the future. Our findings elucidate the mode of COL11A1 expression in very different carcinoma types and may aid to categorise tumours in the setting of possible future COL11A1-related therapies.
Psychometric properties and measurement invariance of the emotion regulation questionnaire in Chinese left-behind children
Authors: Chen Wei , Zhang Guyin , Tian Xue , Wang Li 
Published: August 2021

AbstractLeft-behind children (LBC) is a group of children who live without their parents and receive less parental care and education. Compared with non-left-behind children (NLBC), LBC are more likely to develop emotional or behavior problems. This study aimed to explore the psychometric properties and measurement invariance of the Chinese version of the Emotion Regulation Questionnaire (ERQ) in Chinese LBC. A sample of 2960 middle school students (44.35% male, 55.28% female; age: 12 to 20 years) including LBC (n = 1365) and NLBC (n = 1595) was used. The exploratory factor analysis (EFA); confirmatory factor analyses (CFA); tests of measurement invariance; t-tests of gender and left-behind experience differences; tests of reliability and convergent, discriminant, and criterion validity were conducted. The results showed that two factors were extracted, and the CFA replicated the original two-factor structure (S-Bχ2/df ≈ 106.778/34, P < .001, CFI = .948, TLI = .932, RMSEA = .056 [.044, .068]). The measurement invariance of the ERQ across genders, LBC and NLBC was also confirmed. Males use expressive suppression (ES) significantly more than females (t = 2.63, p < .01), and LBC use ES significantly more than NLBC (t = 2.11, p < .05). The internal consistency coefficients for ES and cognitive reappraisal (CR) were acceptable, and the test-retest reliability was .62 and .68, respectively. Good convergent, discriminant and criterion validity were also demonstrated. It can be concluded that the ERQ is a valid measure for investigating the use of two different emotion regulation strategies among Chinese left-behind children.
Bulbophyllum lanterna, a new species in Dendrobiinae (Orchidaceae) from Madagascar
Authors: Hermans Johan , Rajaovelona Landy , Cribb Phillip 
Published: August 2021

SummaryA new species from Madagascar, Bulbophyllum lanterna Hermans, is described and illustrated. It is compared with similar species from section Lichenophylax. A preliminary conservation assessment is provided.
The mini player with diverse functions: extracellular vesicles in cell biology, disease, and therapeutics
Authors: Thakur Abhimanyu , Ke Xiaoshan , Chen Ya-Wen , Motallebnejad Pedram , Zhang Kui , Lian Qizhou , Chen Huanhuan Joyce 
Published: August 2021

Abstract
Extracellular vesicles (EVs) are tiny biological nanovesicles ranging from approximately 30–1000 nm in diameter that are released into the extracellular matrix of most cell types and in biofluids. The classification of EVs includes exosomes, microvesicles, and apoptotic bodies, dependent on various factors such as size, markers, and biogenesis pathways. The transition of EV relevance from that of being assumed as a trash bag to be a key player in critical physiological and pathological conditions has been revolutionary in many ways. EVs have been recently revealed to play a crucial role in stem cell biology and cancer progression via intercellular communication, contributing to organ development and the progression of cancer. This review focuses on the significant research progress made so far in the role of the crosstalk between EVs and stem cells and their niche, and cellular communication among different germ layers in developmental biology. In addition, it discusses the role of EVs in cancer progression and their application as therapeutic agents or drug delivery vehicles. All such discoveries have been facilitated by tremendous technological advancements in EV-associated research, especially the microfluidics systems. Their pros and cons in the context of characterization of EVs are also extensively discussed in this review. This review also deliberates the role of EVs in normal cell processes and disease conditions, and their application as a diagnostic and therapeutic tool. Finally, we propose future perspectives for EV-related research in stem cell and cancer biology.
Padé approximants on Riemann surfaces and KP tau functions
Authors: Bertola Marco 
Published: August 2021

AbstractThe paper has two relatively distinct but connected goals; the first is to define the notion of Padé approximation of Weyl–Stiltjes transforms on an arbitrary compact Riemann surface of higher genus. The data consists of a contour in the Riemann surface and a measure on it, together with the additional datum of a local coordinate near a point and a divisor of degree g. The denominators of the resulting Padé-like approximation also satisfy an orthogonality relation and are sections of appropriate line bundles. A Riemann–Hilbert problem for a square matrix of rank two is shown to characterize these orthogonal sections, in a similar fashion to the ordinary orthogonal polynomial case. The second part extends this idea to explore its connection to integrable systems. The same data can be used to define a pairing between two sequences of line bundles. The locus in the deformation space where the pairing becomes degenerate for fixed degree coincides with the zeros of a “tau” function. We show how this tau function satisfies the Kadomtsev–Petviashvili hierarchy with respect to either deformation parameters, and a certain modification of the 2-Toda hierarchy when considering the whole sequence of tau functions. We also show how this construction is related to the Krichever construction of algebro-geometric solutions.
Ghrelin Response to Acute and Chronic Exercise: Insights and Implications from a Systematic Review of the Literature
Authors: Ouerghi Nejmeddine , Feki Moncef , Bragazzi Nicola Luigi , Knechtle Beat , Hill Lee , Nikolaidis Pantelis T. , Bouassida Anissa 
Published: August 2021

Abstract
Background
Ghrelin is a peptide hormone predominantly produced by the stomach. It exerts a wide range of functions including stimulating growth hormone release and regulating appetite, food intake, and glucose and lipid metabolism. Since physical exercise affects all these aspects, a particular interest is accorded to the relationship between ghrelin and exercise. This systematic review aimed to summarize the current available data on the topic for a better understanding of the relationship.

Methods
An extensive computerized search was performed in the PubMed and SPORTDiscus databases for retrieving relevant articles. The search contained the following keywords: ghrelin, appetite-related peptides, gastrointestinal peptides, gastrointestinal hormones, exercise, acute exercise, chronic exercise, training, and physical activity. Studies investigating the effects of acute/chronic exercise on circulating forms of ghrelin were included.

Results
The initial search identified 840 articles. After screening, 80 articles were included. Despite a heterogeneity of studies and a variability of the findings, the review suggests that acute exercise suppresses acyl ghrelin production regardless of the participants and the exercise characteristics. Long- and very long-term exercise training programs mostly resulted in increased total and des-acyl ghrelin production. The increase is more noticeable in overweight/obese individuals, and is most likely due to weight loss resulting from the training program.

Conclusion
The review suggests that exercise may impact ghrelin production. While the precise mechanisms are unclear, the effects are likely due to blood flow redistribution and weight loss for acute and chronic exercise, respectively. These changes are expected to be metabolically beneficial. Further research is needed for a better understanding of the relationship between ghrelin and exercise.
Alliance matters: but how much? A systematic review on therapeutic alliance and outcome in patients with anorexia nervosa and bulimia nervosa
Authors: Werz Janina , Voderholzer Ulrich , Tuschen-Caffier Brunna 
Published: August 2021

Abstract
Purpose
Patients with eating disorders (ED) pose a high-risk group regarding relapse. The understanding of factors contributing to a better outcome is much-needed. Therapeutic alliance (TA) is one important, pantheoretical variable in the treatment process, which has shown to be connected with outcome. This review looks into a possible predictive effect of TA on outcome as well as related variables.

Methods
A systematic review with pre-determined inclusion criteria following the PRISMA guidelines was conducted for studies published since 2014. Three previous reviews including studies up until 2014 were analyzed for studies matching our inclusion criteria. A total of 26 studies were included.

Results
The results were heterogeneous between different patient groups. Regarding the predictive effect of TA, in adolescent samples, the TA of either the patients or their parents seems to impact outcome as well as completion. For adults, results are mixed, with a tendency to a greater impact of TA for anorexia nervosa (AN) patients, while some samples of adult bulimia nervosa (BN) patients did not find any relation between TA and outcome.

Conclusion
The effect of TA on clinical outcome depends on the patient group. TA has a greater impact on adolescents, irrespective of diagnosis, and on adults with AN. The examined studies have different limitations which include small sample sizes and questionable study design. The examination of motivation as a potential influencing factor is recommended.

Level of evidence
Level I, systematic review.
Blockchain-based green big data visualization: BGbV
Authors: Shahzad Iqra , Maqbool Ayesha , Rana Tauseef , Mirza Alina , Khan Wazir Zada , Kim Sung Won , Zikria Yousaf Bin , Din Sadia 
Published: August 2021

AbstractThe progression of Internet of Things (IoT) has resulted in generation of huge amount of data. Effective handling and analysis of such big volumes of data proposes a crucial challenge. Existing cloud-based frameworks of Big Data visualization are rising costs for servers, equipment, and energy consumption. There is a need for a green solution targeting lesser cost and energy consumption with tamper-proof record-keeping, storage, and interactive visualization with only demanded data. We have proposed a Blockchain-based Green big data Visualization (BGbV) solution using Hyperledger Sawtooth for optimum utilization of organization resources. BGbV will support current distributed data visualization platforms and guarantee benefits like security and data availability with lesser storage costs. It helps reduce costs by utilizing small resources that are already available and consume less energy, making it an environmentally friendly solution.