bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cheminformatic Profiling and Hit Prioritization of Natural Products with Activities against Methicillin-Resistant Staphylococcus aureus (MRSA)
Authors: Oselusi Samson O. , Egieyeh Samuel A. , Christoffels Alan 
Published: June 2021

Several natural products (NPs) have displayed varying in vitro activities against methicillin-resistant Staphylococcus aureus (MRSA). However, few of these compounds have not been developed into potential antimicrobial drug candidates. This may be due to the high cost and tedious and time-consuming process of conducting the necessary preclinical tests on these compounds. In this study, cheminformatic profiling was performed on 111 anti-MRSA NPs (AMNPs), using a few orally administered conventional drugs for MRSA (CDs) as reference, to identify compounds with prospects to become drug candidates. This was followed by prioritizing these hits and identifying the liabilities among the AMNPs for possible optimization. Cheminformatic profiling revealed that most of the AMNPs were within the required drug-like region of the investigated properties. For example, more than 76% of the AMNPs showed compliance with the Lipinski, Veber, and Egan predictive rules for oral absorption and permeability. About 34% of the AMNPs showed the prospect to penetrate the blood–brain barrier (BBB), an advantage over the CDs, which are generally non-permeant of BBB. The analysis of toxicity revealed that 59% of the AMNPs might have negligible or no toxicity risks. Structure–activity relationship (SAR) analysis revealed chemical groups that may be determinants of the reported bioactivity of the compounds. A hit prioritization strategy using a novel “desirability scoring function” was able to identify AMNPs with the desired drug-likeness. Hit optimization strategies implemented on AMNPs with poor desirability scores led to the design of two compounds with improved desirability scores.
Hemşirelik Öğrencilerinin Covid-19 Pandemi Sürecinde Sağlık Bilişleri ile Depresyon Anksiyete Stres Düzeyleri Arasındaki İlişkisi
Authors: YILDIRIM KESKİN Alev , MOLU Birsel 
Published: June 2021

Giriş ve Amaç: Hemşirelik öğrencilerinin Covid-19 pandemi sürecinde sağlık bilişleri ile depresyon, anksiyete ve stres düzeyleri arasındaki ilişkiyi saptamak amacıyla yapılmıştır.
Gereç ve Yöntemler: Tanımlayıcı ve kesitsel nitelikte olan bu çalışmanın evrenini hemşirelik birinci, ikinci, üçüncü ve dördüncü sınıfta okuyan toplam 245 öğrenci, örneklemini ise 20.06.2020-20.07.2020 tarihleri arasında araştırmaya katılmayı kabul eden 175 öğrenci oluşturmuştur. Veriler araştırmacılar tarafından oluşturulan veri toplama formu, Depresyon Anksiyete Stres (DASS-21) ve Sağlık Bilişleri Ölçeği ile toplanmıştır. Verilerin tanımlayıcı istatistikleri hesaplanmış ve Mann-Whitney U testi, Kruskal-Wallis testi, Post Hoc testlerden Dunn Bonferroni, Spearman Korelasyon analizi uygulanmıştır.
Bulgular: Öğrencilerin Depresyon Anksiyete Stres Ölçeği (DASS-21) toplam puan ortalamasının 15.58±11.78, Sağlık Bilişleri Ölçeği puan ortalamasının 62.41±9.91 ve orta düzeyde olduğu saptanmıştır. DASS-21 Ölçeği alt boyutları ile Sağlık Bilişleri Ölçeği alt boyutları arasında anlamlı bir ilişki bulunmuştur (p
Analisis Kondisi Atmosfer Saat Banjir dan Tanah Longsor (Studi Kasus : Nganjuk, 14 Februari 2021)
Authors: Diniyati Estri , Fa’iz Dwitrisna Muhammad , Mulya Aditya 
Published: June 2021

Indonesia merupakan negara yang rentan terhadap bencana hidrometeorologi karena memiliki potensi pembentukkan awan konvektif yang besar. Pada tanggal 14 Februari 2021, bencana banjir dan longsor melanda wilayah Nganjuk yang menyebabkan kerugian baik harta maupun jiwa. Oleh karena itu, penelitian ini bertujuan untuk mengkaji kondisi atmosfer saat kejadian banjir dan tanah longsor di wilayah Nganjuk. Hasil penelitian menunjukkan bahwa terdapat fenomena La Nina yang sedang aktif di wilayah Indonesia dengan ditandai anomali suhu muka laut di Indonesia menjadi lebih hangat sebesar 1-2℃. Selain itu, terdapat juga pola konvergensi angin yang melewati wilayah Nganjuk sehingga memperbesar potensi pembentukkan awan konvektif pada wilayah tersebut. Berdasarkan citra satelit Himawari-8, dengan menggunakan teknik RGB dan teknik CCO menunjukkan bahwa terdapat awan cumulonimbus yang berinisiasi menjadi awan cumulonimbus multisel. Awan multisel ini menutupi sebagian besar wilayah Jawa Timur pada pukul 08.00-18.00 UTC dengan suhu puncak di wilayah Nganjuk mencapai -77,4℃. Nilai indeks labilitas atmosfer sebelum terbentuknya awan yaitu CAPE sebesar 1600-2200 J/kg dan TT index sebesar 43,5-44. Pada pukul 08.00 UTC, divergensi di lapisan 1000-900 mb menunjukan nilai -0,027s-1 hingga -0,013s-1, kemudian vortisitas sebesar 0,013-0,04 s-1. Nilai kelembapan di permukaan sebelum terbentuknya awan sebesar 80-85% kemudian meningkat saat awan telah memasuki fase tumbuh hingga punah yaitu sebesar 90-100%. Dari hasil tersebut menandakan kondisi atmosfer sedang labil sehingga mendukung terjadinya pertumbuhan awan konvektif. Hasil ini didukung dengan data pengamatan hujan pada wilayah Nganjuk dimana sebagian besar intensitas curah hujan pada wilayah tersebut termasuk dalam kategori hujan lebat hingga hujan sangat lebat mencapai 162 mm/hari.
INVENTARISASI TUMBUHAN OBAT DAN PEMANFAATANNYA SECARA TRADISIONAL OLEH MASYARAKAT DI DESA AMESIU KABUPATEN KONAWE, SULAWESI TENGGARA
Authors: Alkawi Alkawi , Rondonuwu Sendy Beatrix , Kandou Febby Ester Fany 
Published: June 2021

ABSTRACT Amesiu village is one of the areas that has a considerable potency of medicinal plants. This study aims to inventory the types of plants used as medicine and to study the utilization of medicinal plants in the village of Pondidaha Pondidaha District Konawe. This study uses qualitative deskrpative method with data collection techniques through interviews, observations, and documentation. The data of the research results are analyzed descriptively and presented in the form of descriptions, tables and images. The results showed that in Amesiu Village there are 39 species of 27 plant families used by the community as traditional medicine materials. Organs or parts of plants that are utilized as the manufacture of medicinal herbs, namely roots, rhizomes, tubers, stems, bark, leaves, fruits and seeds. The most widely used part of plants as medicine is leaves. The processing process is done by boiling, shredded, pounded and burned. The most widely used way of processing is boiled. Types of diseases that can be treated with medicinal plants as many as 31 types of diseases. Keywords : Inventory, Medicinal Plants, Amesiu Village ABSTRAKDesa Amesiu merupakan salah satu wilayah yang memiliki potensi tumbuhan obat yang cukup banyak. Penelitian ini bertujuan untuk menginventarisasi jenis-jenis tumbuhan yang dimanfaatkan sebagai obat dan untuk mengkaji pemanfaatan tumbuhan obat di Desa Amesiu Kecamatan Pondidaha Kabupaten Konawe. Penelitian ini menggunakan metode deskrptif kualitatif dengan teknik pengumpulan data melalui wawancara, observasi, dan dokumentasi. Data hasil penelitian dianalisis secara deskriptif dan disajikan dalam bentuk deskripsi, tabel dan gambar. Hasil penelitian menunjukkan bahwa di Desa Amesiu terdapat 39 spesies dari 27 famili tumbuhan yang dimanfaatkan oleh masyarakat sebagai bahan pengobatan tradisional. Organ atau bagian tumbuhan yang dimanfaaatkan sebagai pembuatan ramuan obat yaitu akar, rimpang, umbi, batang, kulit batang, daun, buah dan biji. Bagian tumbuhan yang paling banyak digunakan sebagai obat yaitu daun. Proses pengolahan dilakukan dengan cara direbus, diparut, ditumbuk dan dibakar. Cara pengolahan yang paling banyak digunakan adalah direbus. Jenis penyakit yang dapat diobati dengan tumbuhan obat sebanyak 31 jenis penyakit. Kata kunci : Inventarisasi, Tumbuhan Obat, Desa Amesiu
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL SPONS (Mycale vansoesti Sensu) YANG DIKOLEKSI DARI KEPULAUAN MANTEHAGE
Authors: Lampongajo Stela Mahdalena , Yudistira Adithya , Rumondor Erladys 
Published: June 2021

ABSTRACTMycale sponges have potential as antioxidants. Mycale vansoesti Sensu is one of the dominant sponges in the Mantehage Islands, Manado. This study is a laboratory experimental study with the ethanol extract of Mycale Vansoesti Sensu sponge with the DPPH [1,1-diphenyl-2-picrylhydrazyl] method to analyze antioxidant activity using a spectrophotometer. The results of this study show that the antioxidant levels of the Mycale vansoesti Sensu Sponge in the waters of the island of Mantehage have antioxidant activity and the higher the concentration the higher the antioxidant content produced. The greatest antioxidant content is found in the Mycale vansoesti Sensu Sponge with a concentration of 0,35 mg / L. This shows that the extract of the Mycale vansosti Sensu sponge has vital potential as an antioxidant that provides added value in the pharmaceutical industry. Keywords: Antioxidant, DPPH, Mycale vansoesti Sensu, Mantehage Island. ABSTRAKSpons genus Mycale terdapat potensi sebagai antioksidan. Mycale vansoesti Sensu merupakan salah satu jenis spons yang cukup dominan dikepulauan Mantehage, Manado. Penelitian ini merupakan eksperimental laboratorium dengan pengujian terhadap ektrak etanol spons Mycale Vansoesti Sensu dengan metode DPPH [1,1-difenil-2-pikrilhidrazil] untuk menganalisis aktivitas antioksidan dengan menggunakan spektrofotometer. Hasil penelitian ini memperlihatkan kadar antioksidan dari Spons Mycale vansoesti Sensu di perairan pulau Mantehage mempunyai aktivitas antioksidan dan semakin tinggi konsentrasi semakin tinggi pula kadar antioksidan yang dihasilkan. Kadar antioksidan yang paling besar terdapat pada Spons Mycale vansoesti Sensu dengan konsentrasi 0,35 mg/L. Hal ini menunjukkan bahwa ekstrak spons Mycale vansosti Sensu memiliki potensi vital sebagai antioksidan yang memberikan nilai tambah dalam industri farmasi. Kata kunci : Antioksidan, DPPH, Mycale vansoesti Sensu, pulau Mantehage.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK BIJI BUAH DUKU Lansium domesticum TERHADAP BAKTERI STAPHYLOCOCUS AUREUS DAN ESCHERICHIA COLI
Authors: Pehino Albrita , Fatimawali Fatimawali , Suoth Elly J. 
Published: June 2021

ABSTRACT Duku (Lansium domesticum) provides many benefits for the community. Apart from the fruit which has high nutritional value, duku is believed by the community to have benefits. The study aims to learn about the antibacterial extract of my seed against the staphylococus aureus and escherichia coli. This study used the meseration method with ethanol as a solvent. The antibacterial activity test used the well diffusion method with a concentration of 10%, 20%, 30%, 40%. The positive control used was Ciprofloxacin and the negative control used was the CMC solution. Studies show that the suppression of extract is 10%, 20%, 30%, and 40% staphylococus aureus, the average drip zone is 11.3mm, 13.3mm, 13.6mm, 11,3mm, and escherichia coli, on average, 10 mm, 9,3mm, 10,3mm, 12,6 mm. The results suggest that the extract of the duku fruit has antibacterial activity against the growth of the staphylococcus aureus and escherichia coli. Keywords: Duku seed, Antibacterial, Antibacterial activity ABSTRAK Duku (Lansium domesticum) banyak memberikan manfaat bagi masyarakat. Selain buahnya yang mempunyai nilai gizi tinggi, duku dipercaya masyarakat memiliki manfaat untuk kesehatan. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak biji duku terhadap bakteri staphylococus aureus dan Escherichia coli. Penelitian ini menggunakan metode maserasi dengan pelarut etanol. Uji aktivitas antibakteri menggunakan metode difusi sumuran dengan konsentrasi 10%, 20%, 30%, 40%. Kontrol positif yang digunakan adalah Ciprofloxacin dan kontrol negatif yang digunakan adalah larutan CMC. Hasil penelitian menunjukan bahwa daya hambat ekstrak dengan konsentrasi 10%, 20%, 30%, dan 40% Staphylococcus aureus rata-rata zona beningnya 11,3mm, 13,3mm, 13,6mm, 11,3mm, dan Escherichia coli rata-rata zona beningnya 10 mm, 9,3mm, 10,3mm, 12,6 mm. Dari hasil yang didapatkan disimpulkan bahwa ekstrak biji buah duku memiliki aktivitas antibakteri terhadap pertumbuhan bakteri Staphylococcus aureus dan Escherichia coli. Kata Kunci:Biji buah duku, Antibakteri, Aktivitas antibakteri
ANALISIS GC-MS EKSTRAK METANOL DAN N-HEKSAN DARI BUNGA TELANG (Clitoria ternatea L.)
Authors: Ma'ruf Nurul Qalbiyyah , Antasionasti Irma , Fatimawali Fatimawali , Tallei Trina 
Published: June 2021

ABSTRACT The butterfly pea flower (Clitoria ternatea L.) is a flower can grow as an ornamental plant or a wild plant with a single purple petal. This study aims to analyze the phytochemical compounds from butterfly pea flower. The method used is the extraction of dried powder of butterfly pea flowers using methanol and n-hexane solvent then analyzed using GC-MS. The analysis showed that there were 48 possible compounds detected in the methanol extract and 18 possible compounds detected in the n-hexane extract of butterfly pea flower. The compound from the methanol extract which had the highest peak were d-Mannose, d-Glycero-d ido-heptose, and Galacto-heptulose. While the compounds from the n-hexane extract that had the highest peak were Longipinocarvone, Acetic acid, 3-hydroxy-6-isopropenyl-4,8a-dimethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-2 -yl ester, and 10-12-Pentacosadiynoic acid. Keywords : Clitoria ternatea L, butterfly pea flower, GC-MS ABSTRAK Bunga Telang (Clitoria ternatea L.) merupakan bunga yang dapat tumbuh sebagai tanaman hias maupun tanaman liar dengan kelopak tunggal berwarna ungu. Penelitian ini bertujuan untuk menganalisis senyawa fitokimia dari bunga Telang. Metode yang digunakan yaitu ekstraksi serbuk kering bunga Telang menggunakan pelarut metanol dan n-heksan kemudian dianalisis menggunakan GC-MS. Hasil analisis menunjukkan bahwa terdapat 48 kemungkinan senyawa yang terdeteksi dalam ekstrak metanol dan 18 kemungkinan senyawa yang terdeteksi dalam ekstrak n-heksan bunga Telang. Senyawa dari ekstrak metanol yang memiliki puncak tertinggi yaitu d-Mannose, d-Glycero-d ido- heptose, dan Galacto-heptulose. Sedangkan senyawa dari ekstrak n-heksan yang memiliki puncak tertinggi yaitu Longipinocarvone, Acetic acid, 3-hydroxy-6-isopropenyl-4,8a-dimethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-2-yl ester, dan 10-12-Pentacosadiynoic acid.Kata kunci : Clitoria ternatea L, kembang Telang, GC-MS
UJI AKTIVITAS ANTELMINTIK EKSTRAK ETANOL DAUN SIRIH (Piper betle L.) TERHADAP CACING GELANG (Ascaris lumbricoides) SECARA IN VITRO
Authors: Sumual Priskila Feicy , Bodhi Widdhi , Lebang Julianri Sari 
Published: June 2021

ABSTRACTGreen betel leaves are one of the native plants in Indonesia which are widespread in Manado, North Sulawesi. In green betel leaves plants, there are tannin compounds that can inhibit enzymes and interfere with the digestive metabolic processes of worms which can cause the death of worms. This study aims to determine the effect of green betel leaves ethanol extract on Ascaris lumbricoides worms. This research is a laboratory experiment with The post-test only with controlled group design. The tests used the betel leaves ethanol extract with concentrations of 5%, 10%, and 15% respectively. Worms was observed for 12 hours with intervals of 3 hours. The number of worm deaths was recorded every 3 hours and further, it was analysed with using the Kruskal Wallis test and it was continued with using the Mann Whitney test. Result showed that extract at concentration of 5% the number of worm deaths was 4 worms, a concentration of 10% was 7 worms, and at a concentration of 15% 9 worms. The statistical results showed that there was no significant difference between the number of worm deaths in the treatment group and negative control at p <0.05. The concentrations of 10 and 15 showed no significant difference with the positive control. It can be concluded that concentrations of 10% and 15% have the same anthelmintic activity but the best concentration is at a concentration of 10%. Keywords: Anthelmintic, Piper betle L., Ascaris lumbricoides ABSTRAKDaun sirih hijau merupakan salah satu tanaman asli di Indonesia yang tersebar luas di kota Manado, Sulawesi Utara. Pada tumbuhan daun sirih hijau terdapat senyawa tanin yang mampu menghambat kerja enzim dan mengganggu proses metabolisme pencernaan pada cacing yang dapat menyebabkan kematian cacing. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak etanol daun sirih hijau terhadap cacing Ascaris lumbricoides. Penelitian ini ialah eksperimental laboratorium dengan rancangan penelitian The post-test only with controlled group design. Pengujian dilakukan menggunakan ekstrak etanol daun sirih dengan konsentrasi 5%, 10%, dan 15%. Aktivitas cacing diamati selama 12 jam dengan interval waktu 3 jam. Jumlah cacing yang mati dicatat setiap 3 jam dan selanjutnya dianalisis menggunakan uji Kruskal Wallis dan dilanjutkan dengan uji Mann Whitney. Hasil pengujian menunjukkan pada konsentrasi 5% jumlah kematian cacing sebanyak 4 ekor, konsentrasi 10% sebanyak 7 ekor dan pada konsentrasi 15% sebanyak 9 ekor. Hasil statistik menunjukkan tidak ada perbedaan signifikan antara jumlah kematian cacing pada kelompok perlakuan dengan kontrol negatif pada p<0.05. Konsentrasi 10 dan 15 menunjukkan tidak ada perbedaan signifikan dengan kontrol positif. Dapat disimpulkan bahwa pada konsentrasi 10% dan 15% memiliki aktivitas antelmintik yang sama namun konsentrasi yang paling baik terdapat pada konsentrasi 10%. Kata kunci: Antelmintik, Piper betle L., Ascaris lumbricoides
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAN FRAKSI ASCIDIAN (Lissoclinum badium) DARI PERAIRAN PULAU MANTEHAGE
Authors: Woran Falinry , Wewengkang Defny S. , Jayanti Meilani 
Published: June 2021

ABSTRACTLissoclinum badium is a type of ascidian that contains bioactive compounds. This study aims to determine of presence of antibacterial activity from extracts and fractions of Lissoclinum badium collected from Mantehage Island Manado against Escherichia coli and Staphylococcus aureus bacteria. Samples were extracted by maceration method using 95% ethanol solvent and fractionated using solvents of chloroform, n-hexane and methanol. Antibacterial activity was carried out by the disk diffusion agar method. The results showed that the ethanol extracts an methanol fraction had activity to inhibit the growth of Escherichia coli bacteria with strong category. Meanwhile, against the Staphylococcus aureus the ethanol extracts, chloroform and n-hexane fractions had ability to inhibit the growth of bacteria with weak category.. Keywords: Antibacterial activity, Lissoclinum badium, Escherichia coli, Staphylococcus aureus. ABSTRAKLissoclinum badium merupakan salah satu jenis tunikata yang memiliki kandungan senyawa bioaktif yang dapat digunakan untuk pengobatan berbagai penyakit. Penelitian ini bertujuan untuk mengetahui adanya aktivitas antibakteri dari ekstrak dan fraksi Lissoclinum badium yang diperoleh dari Pulau Mantehage Manado terhadap Escherichia coli dan Staphylococcus aureus. Sampel diekstraksi dengan metode maserasi menggunakan pelarut etanol 95% dan fraksinasi menggunakan pelarut metanol, kloroform, dan n-heksan. Aktivitas antibakteri dilakukan dengan metode difusi agar cakram kertas. Hasil penelitian menunjukkan bahwa ekstrak etanol dan fraksi metanol memiliki aktivitas untuk menghambat bakteri Escherichia coli dan Staphylococcus aureus dengan daya hambat kuat. Sedangkan untuk fraksi kloroform dan fraksi n-heksan memiliki aktivitas untuk menghambat bakteri Staphylococcus aureus saja dengan daya hambat sedang. Kata kunci: Aktivitas antibakteri, Lissoclinum badium, Escherichia coli, Staphylococcus aureus.
Strategi Mengatasi Common Measures Bias dalam Balanced Scorecard
Authors: Faradiza Sekar Akrom , Nurmalia Vera Desy 
Published: June 2021

AbstractBalanced Scorecard (BSC) is a comprehensive performance measurement. BSC is not only used financial indicators but also non financial indicators there are customer, internal process business and learning and growth perspective. By using BSC, evaluators have common and unique measures. When evaluate manager performance, evaluator tends to only use common measures and ignore unique measures. This is called common measures bias. This study aims to investigate whether dissaggregated and aggregated BSC and management communication can overcome common measures bias and intent to BSC approach. This study also will evaluate whether these approach will affect evaluator decision when allocated compensation. We conduct 2x2x2 experiment of undergraduate accounting students. Participant act as a senior manager and evaluate the performance of two divisions and then allocated the bonus. ANOVA repeated measurement are used to conduct hypothesis test. The results showed that dissaggregated BSC and management communication could not overcome common measures bias but effected management decision when allocated compensation.
Farm Business Feasibility of Pineapple Commodity after Volcanic Eruption in Ngancar District, Kediri, East Java Province
Authors: Himmati Risdiana , Purwaningsih Yunastiti , Suryantoro Agustinus 
Published: June 2021

This study aims to find and analyze the effect of the input factors of activities undertaken in farm businesses affected by a volcanic eruption on their farm business. This research concentrates on the feasibility of the planted commodity whether it can still be continued with the feasibility value based on the results of the R/C Ratio calculation or not. This study took place in a district located closest and suffered major damage due to the eruption of Mount Kelud in Ngancar District, Kediri Regency, East Java Province. This research used primary and secondary data. This study used the R/C Ratio method to analyze the feasibility of pineapple farm business in the Ngancar District, Kediri Regency. The results of the feasibility analysis of the pineapple farm business using the R/C Ratio show that the pineapple farm business is financially feasible after the eruption of Mount Kelud because it has an R/C ratio more than one.
Implementasi Algoritma Weighted Sum Model dalam Sistem Penjaminan Mutu Perguruan Tinggi
Authors: Pahlevi Ryan Fitrian 
Published: June 2021

Pemerintah Indonesia menyelenggarakan Sistem Penjaminan Mutu (SPM) Pendidikan Tinggi (PT) sebagai usaha dalam mewujudkan pendidikan yang bermutu. Muhammadiyah mengelola Perguruan Tinggi Muhammadiyah/‘Aisyiyah (PTMA) dengan manajemen proses bisnis SPM sebagai bentuk pencapaian mutu Standar Nasional Pendidikan Tinggi (SN-DIKTI). Penjaminan mutu PT ditetapkan dalam Standar Mutu. Banyaknya kriteria dan keterkaitan dengan kegiatan penjaminan mutu menjadi persoalan yang diangkat pada penelitian ini. Penelitian difokuskan pada analisis metode pengambilan keputusan Weighted Sum Model (WSM) dalam Sistem Pendukung Keputusan (SPK) menggunakan algoritma Weighted Sum Model serta pengujian algoritma tersebut dalam implementasi di SPM PTMA. Algoritma WSM digunakan dan diuji pada basis data standar mutu dengan variabel pembanding antar metode yaitu relevansi, ciri, akurasi, presisi, reliabilitas, efektivitas, efisiensi, kelebihan, dan kekurangan. Hasil dan analisis penelitian adalah penggunaan algoritma WSM untuk menentukan prioritas dari 11 Proses Bisnis PT menjadi informasi bagi Pimpinan PTMA dalam memprediksi kegiatan strategis. Proses Analisis telah dilakukan dan diperoleh bahwa algoritma WSM digunakan dalam SPM PTMA dengan skor penilaian uji coba adalah sebesar 94%.

Kata kunci - Sistem Penjaminan Mutu (SPM), Sistem Pendukung Keputusan (SPK), Perguruan Tinggi Muhammadiyah/’Aisyiyah (PTMA), Standar Mutu