bluuebunny/crossref_metadata_2025_split huggingface dataset:
Yield and growth characteristics of a high oil–protein soybean with enhanced diacylglycerol acyltransferase
Authors: AL‐Amery Maythem , Battaglia Martin , Serson William , Sadeghpour Amir , Lee Chad D. , Knot Carrie , Swiggart Ethan , Safari‐Katesari Hadi , Hildebrand David 
Published: December 2021

AbstractIntroduction of the VgDGAT1A gene in soybean [Glycine max (L.) Merr.] genotypes increased both protein and oil content and resulted in earlier maturation compared with commonly cultivated soybean genotypes (i.e., Jack). However, the effect of VgDGAT1A gene on the length of the vegetative, reproductive, and the overall growth period of soybean has not been thoroughly evaluated. A randomized complete block design consisting of two transgenic soybean genotypes with VgD1‐1 and VgD1‐2 highly active acyl‐CoA: diacylglycerol acyltransferase (DGAT) from ironweed [Vernonia galamensis (Cass) Less.] and nontransgenic control (Jack) was evaluated in field studies in 2015 and 2016 in Lexington, Kentucky. Levels of sucrose accumulation and seed weight were calculated for the three genotypes. Soybean grain yield, seed weight, and seed number were similar among all genotypes in both years. Modified genotypes reached the R7 (beginning of physiological maturity) stage earlier, and the rate of dry weight accumulation in individual seeds ranged between 2.8 to 4.4 mg seed−1 day−1 and was not different in comparison with the control (range: 3.4–4.7 mg seed−1 day−1). While days to reach R7 was shorter in VgD, there were no differences among genotypes for pod weight (PW), seed weight (SW), pod sucrose (PS), or seed sucrose (SS) concentrations. Linear plateau and cubic models were the best fit for seed weight for both years. These results indicated that despite earlier maturation in VgD genotypes, seed growth, and final soybean yield were similar among VgD and Jack.
Cardiac arrest due to liquid nicotine intoxication: a case report
Authors: Iida Atsuyoshi , Fujiwara Yuki , Nojima Tsuyoshi , Naito Hiromichi , Nakao Atsunori , Mikane Takeshi 
Published: December 2021

BackgroundWith the introduction of electronic cigarettes, reports of nicotine intoxication due to ingestion of large amounts of liquid nicotine have increased. This report presents a rare case of cardiac arrest due to nicotine intoxication that was successfully treated with appropriate respiratory and circulatory support.Case PresentationA 55‐year‐old man ingested 600 mg of liquid nicotine and developed sinus bradycardia followed by asystole. Appropriate and prompt resuscitation led to the return of spontaneous circulation. He was admitted to the intensive care unit and discharged 24 days later without any medical sequelae of nicotine intoxication.ConclusionIngestion of a large amount of liquid nicotine, as in this case, can result in lethal bradycardia followed by cardiac arrest. Prompt basic life support by paramedic produced good neurological outcomes. Emergency physicians should be aware of the symptoms and appropriate treatment of severe nicotine intoxication.
Network Localization of Unconscious Visual Perception in Blindsight
Authors: Kletenik Isaiah , Ferguson Michael A. , Bateman James R. , Cohen Alexander L. , Lin Christopher , Tetreault Aaron , Pelak Victoria S. , Anderson Clark Alan , Prasad Sashank , Darby Richard Ryan , Fox Michael D. 
Published: December 2021

ObjectiveBlindsight is a disorder where brain injury causes loss of conscious but not unconscious visual perception. Prior studies have produced conflicting results regarding the neuroanatomical pathways involved in this unconscious perception.MethodsWe performed a systematic literature search to identify lesion locations causing visual field loss in patients with blindsight (n = 34) and patients without blindsight (n = 35). Resting state functional connectivity between each lesion location and all other brain voxels was computed using a large connectome database (n = 1,000). Connections significantly associated with blindsight (vs no blindsight) were identified.ResultsFunctional connectivity between lesion locations and the ipsilesional medial pulvinar was significantly associated with blindsight (family wise error p = 0.029). No significant connectivity differences were found to other brain regions previously implicated in blindsight. This finding was independent of methods (eg, flipping lesions to the left or right) and stimulus type (moving vs static).InterpretationConnectivity to the ipsilesional medial pulvinar best differentiates lesion locations associated with blindsight versus those without blindsight. Our results align with recent data from animal models and provide insight into the neuroanatomical substrate of unconscious visual abilities in patients. ANN NEUROL 2022;91:217–224
Rare‐earth metal‐catalyzed hydroboration of unsaturated compounds
Authors: Nie Kun , Han Yinfeng , Wang Changan , Cheng Xueli 
Published: December 2021

AbstractThe reduction of unsaturated compounds is one of the most widely applied transformations in organic synthesis. Aggressive reductants, highly pressurized hydrogen gas, and stoichiometric amount of metal salts used have greatly burdened the environment, stimulating the development of catalytic approaches with milder and greener conditions. In this context, the hydroboration has attracted great attention, and great progress has been achieved in the past decades. Due to the great performance of rare‐earth complexes in numerous organic transformations, such complexes are also employed as catalysts in the hydroboration of different unsaturated compounds. The current review summarized recent works of rare‐earth complexes catalyzed hydroboration of various unsaturated compounds, covering the publications mainly in past 5 years albeit with alkenes as exception. The transformations are mainly classified into two categories: hydroboration of C–C and C–hetero unsaturated compounds, and some closely related works are also discussed, such as rare‐earth catalyzed direct borylation of C–H bonds.
A review of behavioral treatments for sleep disturbances in civilians who have experienced trauma
Authors: Roche Laura , McLay Laurie , Sigafoos Jeff , Whitcombe‐Dobbs Sarah 
Published: December 2021

AbstractSleep disturbances have frequently been associated with trauma and post‐traumatic stress disorder (PTSD). Effective treatments for sleep disturbances are therefore likely to be indicated for individuals who have experienced trauma. With the aim of advancing evidence‐based practice in this area, this review focuses on studies evaluating behavioral treatments for sleep disturbances among civilians who have experienced trauma. Seventeen studies were identified that met inclusion criteria. Data were extracted from each study on (a) the type of sleep disturbance experienced, (b) assessments used, (c) treatment procedures, (d) outcome measures, and (e) main findings. Research quality was also evaluated. The results of these 17 treatment studies were generally positive, but ratings of the strength of the research varied from strong to weak. Overall, this review finds evidence to support the use of behavioral treatments for sleep disturbances resulting from experiences of trauma. The implications of these findings for clinical practice are discussed.
Deterministic transfer of thin carbon nanotube film
Authors: Park Minsuk , Ju Sang‐Yong 
Published: December 2021

AbstractAlthough successfully implemented for optoelectronic devices of two‐dimensional materials, deterministic transfer for thin single‐walled carbon nanotube (SWNT) film has not been realized. Herein, we report a transfer method of few hundreds nanometer‐thick SWNT film to a desired prepatterned substrate position with few micrometer precision. This method comprises poly(methyl methacrylate) (PMMA)‐coated SWNT film, creating surface anisotropy on both sides for SWNT film transfer, and two sets of translators manipulating the film to desired position and angle. Especially, adsorption and desorption of PMMA‐coated SWNT film by each translator were modulated by use of interfacial water which not only promotes PMMA side to the transient sample loader via water capillary and releases the final substrate with capillary assisted sliding. Successful transfer of thin SWNT film with few tens of micrometer precision was achieved and will be beneficial for the preparation of high‐end optoelectronic devices.
Solvation structure of phosphonium ionic liquid/CH3SCN mixture as electrolytes for Li‐ion batteries: Infrared pump‐probe spectroscopic studies
Authors: Sahu Prabhat Kumar , Kim Jungyu , Park Kwanghee , Kim Eunchan , Mondal Saptarsi , Kwak Kyungwon , Cho Minhaeng 
Published: December 2021

AbstractLithium‐ion battery (LIB) electrolytes based on room‐temperature ionic liquids (RTIL) are promising as safe and sustainable LIB electrolytes. However, there are no reports on the solvation structure and dynamics of RTIL due to the existence of various solvation species in RTIL. Here, we investigated the solvation structure and dynamics of binary mixtures of the phosphonium ionic liquid, tributyl(2‐methoxyethyl)phosphonium bis(trifluoromethanesulfonyl)imide (P444102TFSI), and methylthiocyanate (CH3SCN), with ultrafast mid‐IR Spectroscopy. The changes of vibrational and rotational dynamics of CH3SCN∙∙∙Li+ complex and free CH3SCN with an increase in CH3SCN concentration suggest the presence of at least four solvation species, providing superior resolving power for various solvation species existing in complex LIB electrolytes. Our experimental results show that the environment of free CH3SCN and CH3SCN∙∙∙Li+ complex changes drastically with change in CH3SCN mole fraction and Li salt concentration in the mixture. We expect that this can affect the Li‐ion transport mechanism in the IL‐based electrolytes.
Fetal alcohol spectrum disorders (FASD) and youth firesetting: A call on criminal justice, emergency responder, and fire prevention specialists to become informed
Authors: Brown Jerrod , Spiller Vanessa , Carter Megan , Osmonson Kathi , Porth Don , Bishop‐Deaton Deanna , Jozan Amy 
Published: December 2021

AbstractCentral nervous system damage resulting from prenatal exposure to alcohol, often referred to as fetal alcohol spectrum disorders (FASD), commonly manifests as lacking cognitive functioning, problem solving, impulsivity, memory, executive functioning, and social skill deficits. For individuals with FASD, these brain‐based deficits translate into impulsive behaviors and poorly thought‐out decision‐making, coupled with an inability to anticipate and recognize the sometimes very severe consequences of their behaviors. Not unexpectedly, individuals with FASD frequently find themselves disproportionately involved in the criminal justice system and mental health services. For some individuals with FASD, these behaviors can also include firesetting. First responders, like other health and legal professionals, are often unable to recognize the behavioral indicators of FASD, primarily due to a lack of training. As a result, firesetting behaviors are often attributed to deliberate, willful acts of delinquency, a desire to damage property, thrill seeking, or as attempts for personal gain, rather than being viewed as maladaptive attempts to solve problems by individuals who lack the tools to do this in more appropriate ways. These same skill deficits also present when individuals with FASD are interviewed about their involvement in such behaviors, sometimes resulting in confabulation, suggestibility, and false confessions. Further education and training in FASD are vital for first responders if they are to better support individuals with FASD and minimize their chances of becoming involved in firesetting behaviors. Furthermore, this training and education will help ensure that first responders can intervene in more appropriately when crisis situations do occur. This article will outline key behavioral symptoms of FASD as well as provide first responders with suggestions as to how to best support individuals when FASD is suspected. The brief quote that follows highlights some of the key challenges facing individuals with FASD and how poor decision‐making and impulsiveness can result in severe consequences for the individual and those around them.
Trends in a study on thermal runaway mechanism of lithium‐ion battery with LiNixMnyCo1‐x‐yO2 cathode materials
Authors: Zhang Hao , Wang Li , He Xiangming 
Published: December 2021

AbstractSafety failure, especially the “thermal runaway (TR),” result in safety anxiety and hinder the fast development of LIBs. Understanding the process and mechanism are the premise of mitigation TR. In this perspective, we briefly review the progress of the TR study of LIBs and then discuss the recent works on the mechanism study of LIB with different cathodes. We present our latest data of LiNixMnyCo1‐x‐yO2 cathode TR study and rethink the role of liquid electrolytes in TR. At last, we discuss the current‐best known knowledge of investigating the TR mechanism and briefly summarize the strategies for TR alleviation.
Alkynylgold(I) C3‐Chiral Concave Complexes: Aggregation and Luminescence
Authors: Zhang Jing , Schaly Astrid , Chambron Jean‐Claude , Vincent Bruno , Zorn Nathalie , Leize‐Wagner Emmanuelle , Jean Marion , Vanthuyne Nicolas 
Published: December 2021

AbstractChiral gold(I) acetylide trinuclear complexes 1–3 based on the cyclotribenzylene platform and terminal PR3 ligands (R=Ph, Et, and Cy, respectively), were characterized and their light emission studied. They exhibited long‐lived blue phosphorescence in CHCl3 and a weak fluorescence in the UV. In MeOH/CHCl3 mixtures of >1:1 volume ratio, 1 and 2 exhibited a new emission band at ca. 540 nm that developed at the expense of the UV emission. DLS studies demonstrated the presence of molecular aggregates of Ø 30–80 nm. The green emission observed in MeOH‐rich solvent mixtures was therefore induced by aggregation, and could originate from Au⋅⋅⋅Au interactions. The AIE spectrum of 3 was observed only in solutions containing 99 % of MeOH, and correlated with its solid state emission. The AIE profiles of the enantiomers of 1 differed from that of rac‐1, suggesting that the latter is a true racemate.
Multifaceted Role of Microalgae for Municipal Wastewater Treatment: A Futuristic Outlook toward Wastewater Management
Authors: Goswami Rahul Kumar , Agrawal Komal , Verma Pradeep 
Published: December 2021

AbstractMunicipal wastewater (MWW) or urban wastewater (UWW) is generated by the domestic consumption of freshwater, which contains a huge amount of nutrients. The release of unprocessed wastewater causes eutrophication and harms aquatic life. Moreover, ingestion of polluted MWW causes a severe negative impact on human health. Microalgae are unicellular, eukaryotic photosynthetic organisms and have the capability of nutrient assimilation in the presence of light. Moreover, the produced biomass can be used for the generation of value‐added bioproducts such as bioenergy. However, conventional microalgae‐based MWW treatment is not as sustainable on a commercial scale. Therefore, more advanced approaches using microalgae need to be integrated in wastewater cultivation systems to improve nutrient removal efficiency. Thus, the present review explores the use of microalgae for the removal of nutrients from MWW, provides an outlook of direct and indirect methods of nutrient uptake from wastewater and the effects of the influencing factors in biomass growth. Moreover, the review also gives insight into recent approaches used for MWW treatment and the applications of algal biomass resulting from treated wastewater. It is predicted that microalgae‐based MWW treatment systems will be a significant green approach to help eliminate nutrient loads and implement circular economy.
Genetic variants in Hippo pathway genes are associated with house dust mite‐induced allergic rhinitis in a Chinese population
Authors: Chen Min , Zheng Rui , Li Fei , Xin Jun‐Yi , Chen Si‐Lu , Zhu Xin‐Jie , Gu Xiang , Dai Meng‐Di , Yang Yi‐Fan , Chu Hai‐Yan , Zhang Zheng‐Dong , Lu Mei‐Ping , Cheng Lei 
Published: December 2021

AbstractBackgroundHouse dust mite (HDM)‐induced allergic rhinitis (AR) is a highly prevalent disease with bothersome symptoms. Genetic variants of the Hippo pathway genes play a critical role in the respiratory disease. However, no study has reported associations between variants of the Hippo pathway genes and HDM‐induced AR risk.MethodsForty‐three key genes in the Hippo pathway were selected from the Kyoto Encyclopedia of Genes and Genomes (KEGG), Reactome pathway database, and previous reported studies. A case‐control study of 222 cases and 237 controls was performed to assess the associations between 121 genetic variants in these genes and HDM‐induced AR risk. DNeasy Blood & Tissues Kits were used for extracting genomic DNA from the venous blood and Infinium Asian Screening Array BeadChips for performing genotyping. A logistic regression model was applied to evaluate the effects of variants on HDM‐induced AR risk. The false discovery rate (FDR) method was utilized to correct for multiple testing. The receiver operating characteristic (ROC) curve was plotted to obtain the cut‐off value of total IgE for the diagnosis of HDM‐induced AR. Histone modification and transcription factor binding sites were visualized by UCSC genome browser. Moreover, expression qualitative trait loci (eQTL) analysis was obtained from Genotype‐Tissue Expression (GTEx) database.ResultsWe found that rs754466 in DLG5 was significantly associated with a decreased HDM‐induced AR risk after FDR correction (adjusted odds ratio [OR] = 0.52, 95% confidence interval [CI] = 0.36–0.74, p = 3.25 × 10−4, PFDR = 3.93 × 10−2). The rs754466 A allele reduced the risk of HDM‐induced AR in the subgroup of moderate/severe total nasal symptom score (TNSS). Furthermore, rs754466 was associated with a high mRNA expression of DLG5. Additionally, histone modification and transcription factor binding sites were rich in the region containing rs754466.ConclusionOur findings indicated that rs754466 in DLG5 decreased the susceptibility to HDM‐induced AR.
Peripheral blood parameter abnormalities precede therapy‐related myeloid neoplasms after autologous transplantation for lymphoma
Authors: Bachiashvili Kimo , Francisco Liton , Chen Yanjun , Bosworth Alysia , Forman Stephen J. , Bhatia Ravi , Bhatia Smita 
Published: December 2021

BackgroundTherapy‐related myeloid neoplasms (t‐MN) are a leading cause of nonrelapse mortality after autologous peripheral blood stem cell transplantation (aPBSCT) in patients with Hodgkin lymphoma (HL) and non‐Hodgkin lymphomas (NHL). t‐MN patients treated at an earlier stage of disease evolution have a better prognosis, and this presents a need to identify patients at risk for t‐MN.MethodsUsing a prospective longitudinal study design, this study evaluated peripheral blood parameters pre‐aPBSCT and on day 100, at 6 months, 1 year, 2 years, and 3 years in 304 patients treated with aPBSCT. The relation between peripheral blood parameters and subsequent development of t‐MN was examined, and nomograms were developed to identify patients at risk for t‐MN.ResultsTwenty‐one patients developed t‐MN at a median of 1.95 years post‐aPBSCT. Hemoglobin, hematocrit, white blood cell, and platelet counts were lower among patients who developed t‐MN compared to those who did not; these differences appeared soon after aPBSCT, persisted, and preceded development of t‐MN. Older age at aPBSCT (hazard ratio [HR]per_year_increase = 1.08, P = .007), exposure to total body irradiation (TBI) (HR = 2.90, P = .04), and low 100‐day platelet count (HRincrease_per_unit_decline_in_PLT = 1.01, P = .002) predicted subsequent t‐MN. These parameters and primary diagnosis allowed identification of patients at high risk of t‐MN (eg, an HL patient undergoing aPBSCT at the age of 70 years with TBI and with a day 100 PLT between 100,000 and 150,000 would have a 62% probability of developing t‐MN at 6 years post‐aPBSCT).ConclusionsAbnormalities in peripheral blood parameters can identify patients at high risk for t‐MN after aPBSCT for HL or NHL, allowing opportunities to personalize close surveillance and possible disease‐modifying interventions.
Genome‐wide association mapping of Hagberg falling number, protein content, test weight, and grain yield in U.K. wheat
Authors: White Jon , Sharma Rajiv , Balding David , Cockram James , Mackay Ian J. 
Published: December 2021

AbstractAssociation mapping using crop cultivars allows identification of genetic loci of direct relevance to breeding. Here, 150 U.K. wheat (Triticum aestivum L.) cultivars genotyped with 23,288 single nucleotide polymorphisms (SNPs) were used for genome‐wide association studies (GWAS) using historical phenotypic data for grain protein content, Hagberg falling number (HFN), test weight, and grain yield. Power calculations indicated experimental design would enable detection of quantitative trait loci (QTL) explaining ≥20% of the variation (PVE) at a relatively high power of >80%, falling to 40% for detection of a SNP with an R2≥ .5 with the same QTL. Genome‐wide association studies identified marker‐trait associations for all four traits. For HFN (h2 = .89), six QTL were identified, including a major locus on chromosome 7B explaining 49% PVE and reducing HFN by 44 s. For protein content (h2 = 0.86), 10 QTL were found on chromosomes 1A, 2A, 2B, 3A, 3B, and 6B, together explaining 48.9% PVE. For test weight, five QTL were identified (one on 1B and four on 3B; 26.3% PVE). Finally, 14 loci were identified for grain yield (h2 = 0.95) on eight chromosomes (1A, 2A, 2B, 2D, 3A, 5B, 6A, 6B; 68.1% PVE), of which five were located within 16 Mbp of genetic regions previously identified as under breeder selection in European wheat. Our study demonstrates the utility of exploiting historical crop datasets, identifying genomic targets for independent validation, and ultimately for wheat genetic improvement.
Effects of trapped ions concentration on the dynamics of dust‐acoustic periodic travelling waves in dusty plasmas
Authors: Selim M.M. , Abdelaleem H. , El‐Bedwehy N.A. , El‐Shamy E.F. 
Published: December 2021

AbstractThis study is essentially an attempt to investigate the effects of trapped ions concentration on the dynamics of dust‐acoustic (DA) periodic travelling waves in dusty plasmas, which consist of dust fluid, trapped ions, and Maxwellian electrons. The physical nature of DA solitary and periodic travelling waves in the plasma model at hand is governed by a Korteweg‐de Vries (KdV) type equation. Bifurcation analysis of the Hamiltonian system is applied to demonstrate the probability of the presence of DA solitary and periodic travelling waves for the KdV type equation. A careful discussion illustrates that non‐linear phenomena of DA solitary and periodic travelling waves are modified due to the presence of the trapped ions concentration. It is found numerically that the negative amplitude of DA periodic travelling waves is amplified, as the trapping parameter that determines the number of the trapped ions is increased. The numerical simulation gives rise to significant highlights on the dynamics of solitary and periodic travelling waves in astrophysical environments such as Saturn's moon Enceladus.