bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Different Technique of Eliciting the Planter Reflex in Term Neonates
Authors: Taksande Amar , Rao Rupesh , Yedve Sachin , Jameel Patel Zeeshan , Meshram Revat 
Published: June 2021

Background: Planter reflex is still an essential part of the neurological examination. The usual plantar reflex involved bending of the big toe or no response. There is a positive Babinski signal with corticospinal dysfunction, which involves big toe dorsal flexion and the accompanying fanning of the other toes. It’s one of the infant reflexes that disappers as the infant nervous system grows. The plantar reaction is primarily extensive in stable, term neonates. Many have researched this reflex's accuracy but very few studies have analyzed the various techniques of the planting reflex.
Objective: To assess the five different technique of eliciting the plantar reflex in newborn babies.
Materials and Methods: In this cross-sectional study, the eligible healthy newborn will be given the different methods for the elicitation of the plantar reflex i.e. Oppenheim sign, Gordon sign, Gonda’s sign, Chaddock sign, and Schaefer sign. During this procedure, we will record the baseline RR, HR, and SpO2 before, and after the procedure. Three pediatric residents of the different years will be selected for examining the newborn reflexes throughout the study period.
Results: After completion of the study, we will come to know the negative likelihood ratio, negative predictive value, positive predictive, specificity, positive likelihood ratio, and sensitivity of the Oppenheim sign, Gordon sign, Gonda’s sign, Chaddock sign, and Schaefer sign.
Conclusion: The study will probably give us information about the sensitivity and specificity of the Oppenheim sign, Gordon sign, Gonda’s sign, Chaddock sign, and Schaefer sign for the elicitation of the plantar reflex in the neonates.
Importance of Risk Communication and Risk Analysis in Medical Device Industry
Authors: Sharma Akash , Luthra Gaurav 
Published: June 2021

In medical device industry the risk management plays a very vital role. There should be proper communication from each and every stakeholder related to risk management of each respective department, it can be Production, Design and Development or Quality Control and all other departments. In this current research work the role of risk analysis which had been done accordingly ISO 14971 for risk management of medical device using FMEA is implemented. FMEA (Failure Mode and Effects Analysis) plays important role in risk analysis by having several steps for mitigation of risk. Also it had been used for identifying hazard of each risk throughout the lifecycle of the medical device. Risk communication should be advanced so, that the risk identified can be easily controlled by taking appropriate risk control measures. In any medical device industry risk analysis should be done properly and as well the risk communication channel should be strong for proper and immediate action. In this research paper practically the role of Risk communication and risk analysis is covered. Risk management of any of the organization can only be effective if the risk analysis is done strongly and the communication related to risk is proper. In this research FMEA analysis for risk analysis is done on a medical device and also the communication from risk manager to the other entire stakeholders of the risk management from various departments are fully taken into the consideration.
Study on Prevalence of Hyperlipidemia among Medical Students in Wardha District – A study Protocol
Authors: Pawar Pooja , Tirpude Saroj , Parwe Shweta , Nisargandha Milind 
Published: June 2021

Background: Hyperlipidemia is a therapeutic word that indicates unusually increased levels of lipids in the blood, which is generally termed as increased cholesterol. There are mainly 2categories of cholesterol known as high-density lipoprotein, also known as good cholesterol and low-density lipoprotein, also called as bad cholesterol. However, hyperlipidemia can be inherited, resulting in an unhealthy lifestyle and sedentary lifestyle and regular intake of oily food, junk food , fatty food rich in cholesterol, etc.
Aim: Aim is to study the Prevalence of hyperlipidemia among medical students in Wardha District.
Objectives: To determine the dietary pattern among medical students and evaluate the level of lipid profile among medical students.
Methodology: Cross-sectional observational study will be done on medical students of the Wardha district. Based on a well-structured questionnaire on each student's dietary schedule and by collecting fasting blood sample for lipid profile test to observe the level of HDL and LDL in the blood and to observe the Prevalence of hyperlipidemia among medical students in Wardha district of 18 and above years of age group. Written consent of the subject will be taken before collecting their blood samples.
Results: The result will be analyzed statistically based on the study.
Conclusion: Conclusion will be based on observation and analyzed data.
Association of Peripartum Cardiomyopathy with Pre-eclampsia and Maternal Outcome
Authors: Abbas Sabreena , Yousfani Sajida , Shaikh Fouzia , Sultana Farhat , Shaikh Najma , Tahira Sidra 
Published: June 2021

Objective: To determine the Prevalence of Pre-eclampsia in women with peripartum cardiomyopathy (PPCM) and to compare the maternal outcome in cases of PPCM who develop pre-eclampsia with those cases who are normotensive.
Study design: This is a prospective observational study.
Setting: Study carried out at department of Gynecology and Obstetrics, Liaquat university hospital Hyderabad from 20th February 2019 to 19th February 2020.
Materials and methods: This prospective observational study was conducted in department of Gynecology and Obstetrics and department of Cardiology Liaquat University Hospital Hyderabad. Inclusion criteria were patients admitted with a diagnosis of peripartum cardiomyopathy diagnosed clinically and confirmed by echocardiography. Exclusion criteria were cases with multiple pregnancies, smokers, those with chronic hypertension and chronic renal disease or diabetes. We assessed patients for pre-eclampsia. Outcome measures studied were serious maternal complications like Pulmonary oedema, Cardiogenic shock, intensive care unit admission, and death.
Results: During one year study period, there were 71 cases of peripartum cardiomyopathy. The mean age of patients was 29.77±6.8 years. Pre-eclampsia was seen in 62% cases of Peripartum cardiomyopathy. Mean ejection fraction was 33.24±6.49. In patients of PPCM, serious maternal complications including cardiogenic shock 11(15.5%) cases, intensive care unit admission 10(14.1%) cases, pulmonary oedema 35(49.3%) cases and prolonged hospitalization 58(81.7%) cases.
Conclusion: We conclude that pre-eclampsia has high prevalence in patients with PPCM. Both when combined, significantly increase the chances of serious maternal complications including death.
Perceptions of Athletes about Usage of Painkiller Medications for Fatigue Slackening during Sport Trainings
Authors: Javed Saeed , Naseer Abida , Gill Sajjad Ali , Ayub Fehmida , Shariff Abd Rahim Mohd , Din Badar Mohy ud , Sonfada Usman Ibn , Khan Imran U. , Gul Faryal , Naveed Qasid , Javed Waheed 
Published: June 2021

Objective: The purpose of the present research was to find out the perceptions of athletes about the usage of painkiller medications for fatigue relief while their sport trainings.
Methodology: The data was collected from the athletes (n-80) having vast sport experiences who belonged to two public sector universities through online questionnaires. Afterwards, the collected data was edited into SPSS (v.26) and further analyzed the responses through descriptive statistics.
Results: The majority of the athletes affirmed their intake of painkiller medications for the purpose of getting relief to their working group of muscles without claiming any harm or threat physically.
Conclusion: These painkillers may be a source of less fatigue and provision of better blood flow to the working muscles of the athletes. Therefore, the athletes should use the painkillers with consultation of the doctor so that they may save themselves from their side effects if any.
A Comparative Evaluation of Efficacy of Mustadi Yapan Bastiand Baladi Yapan Basti in the Management of Oligozoospermia-Study Protocol
Authors: Ahire Abhijit Murlidharrao , Parwe Shweta , Nisargandha Milind 
Published: June 2021

Background: Nowadays most upcoming disease that affecting 8 to 12% of the world population is Infertility.The affected area of this problem have no bar irrespective of metro cities as well as small towns population..Modern treatment with steroids and other medication and interventions shows limited results.Bastichikitsa itself is the best remedies explained in Ayurved text for the treatment of ksheenshukra.Yapan Basti in Ayurveda is known for its action as balya, i.e. giving strength to the sharirdhatu.Incase of Oligozoospermia there is vitiation and loss of formation process of shukradhatu properly as per Ayurveda. Using YapanBasti,the strength of Shukradhatu can be regain and ultimately correction can be seen in oligozoospermia cases. By doingbastikarma,we are trying to establish and confirm the role of yapanbastiexplained in Ayurvedonoligozoospermia.
Aims and objectives: To study the efficacy of MustadiYapan Bastion sperm count sperm motility, semen volume.SemenPH,abnormal sperm count along with serum testosterone,GH and FSH level in the management of Oligozoospermia in comparison with BaladiYapanBasti.
Methodology: Age ranging between 25 to 50 years will be considered for the study. Secondly Sperm count < 15 million/ml will be consider for the study, also the patients who shows cardinal symptom i.ePratyatmakaLakshana of KshinaShukra, Pathological sample of Semen sample must suggestive of oligozoospermia will be considered for the study.30 Patients in each group will be given Basti for 16 days as explained in classics of Ayurveda .The process of giving basti will be using bastiputak,Basti will be prepared as per the niruhabasti preparation method.Bastigamankal and bastipratyagamankal will be observed properly.Follow-up will be taken after 28thday from starting of treatment.
Results: Results will be drawn from the observations of objective parameters.
Conclusion: MustadiYapanBasti will be effective in oligozoospermia.
Outcomes of Newly Diagnosed Patients of Peripartum Cardiomyopathy at Liaquat University Hospital, Hyderabad, Sindh, Pakistan
Authors: Razzaq Atiya , Memon Shahid Hussain , Arain Zain Islam , Khushk Suhayb Ahmad , Ali Anwar , Bhutto Abdul Qadir 
Published: June 2021

Objective: To determine the outcomes of newly diagnosed patients of peripartum cardiomyopathy at Liaquat University Hospital, Hyderabad.
Methodology: Total 91 patients of peripartum cardiomyopathy were included. A detailed medical history and base line equitable investigations were done. Patients were kept under observation for 7 days during their hospital stay and study outcomes were recorded. Descriptive statistics were calculated. Stratification was done and post stratification chi square test or fisher exact test was applied. Two sided P-value ≤0.05 was considered as significant.
Results: The overall mean age was 29.06±4.71 years. Total 73.6% patients were belonged to urban and 26.4% belonged to rural areas. 52.7% patients had normal delivery while 40% had C-section and 6.6% had instrumental assisted deliveries. As far as outcomes are concerned, 65.9% patients had congestive heart failure, 12.1% patients had arrhythmias, 35.2% patients admitted in ICU, 64.8% patients admitted in recovery and 7.7% patients were died.
Conclusion: In a prospective cohort with PPCM, most women recovered; however, rates of CHF were observed significantly in patients with diabetes mellitus and hypertension. In-hospital mortality was comparatively less frequent but it was significantly associated in women having age less than 30 years.
A Comparative Study on the Efficacy of Kantkari and Vasa Lozenges in Children with Kasa (Cough)-Study Protocol
Authors: Ali Sabir , Rathi Renu , Rathi Bharat 
Published: June 2021

Background: Kasa is the outcome due to release of obstructed Vayu resulting in the production of abnormal sound, which may be productive or dry. Kasa is one of the primary diseases of Pranavaha srotas, and can cause disturbances in other body functions. Prevalence of cough in India is 5% to 10% while acute cases of cough is 39% and chronic cases of cough is 29% reported in Maharashtra. This research drug is taken to check its efficacy on both the types of cough, dry as well as productive with acute or chronic origin. It has a good palatability and liked by children as it appears as candy. Many studies have been carried out on Kasa with different formulations so far like vati, churna, ghrita but they have no fast and long lasting action with different level of efficacy. Many lozenges are also available in the market but no studies have been done.
Objective: Comparative Study on the efficacy of Kantakari lozenges with Vasa lozenges in the clinical features of Kasa by subjective criteria such as Peenasa-(running nose), Kasa, Aruchi-(taste impliedness), kanthkandu(throat itching), kaphnishthivan (Sputum) and objective criteria as adventitious sound and AEC-absolute eosinophil count, TLC-total leucocytes count, and DLC-differential leucocyte count.
Materials and Methods: The present study is designed as a Double Blind, Randomized Controlled Study in which total 60 patients will be enrolled. Patients will be randomly divided (by computer generated sequence method) in two with 30 patients in each group. In group A, Vasa lozenges and in group B Kantkari lozenges will be given for 7 days. Assessment of the patients will be done on 3rd and 7th day during study after intervention and post treatment follow up will be taken on 14th& 21st day from the enrolled date.
Results: Efficacy of both the lozenges will be observed in subjective and objective outcomes. Conclusion: Kantkari lozenges (trial group) is expected to be more effective than Vasa lozenges (control group) in the management of Kasa as Vata, Kapha are more dominant in the pathology of Kasa in children and Kantakari is a good Vatakaphahar drug added with Pippali to act synergistically.
Atlanta Classification for Acute Pancreatitis- A Study Protocol
Authors: Singh Varun , Dhande Rajasbala Pradeep , Mishra Gaurav 
Published: June 2021

Background: Acute pancreatitis is one of the most common abdominal pathologies having variable outcome ranging from self limiting abdominal pain to high mortality and morbidity due to organ failure, over the past five decades, various classification systems have emerged to classify pancreatitis according to its severity , and the associated complications have emerged to classify acute pancreatitis and its various complications, such as Apache Scoring , Ct Severity , Modified Ct Severity ,Ransen and Atlanta Classification.
Objectives: We in our study will be classifying patients suffering from acute pancreatitis according to the revised Atlanta classification to divide them into interstitial edematous pancreatitis and necrotizing pancreatitis. The local complications will be classified according to CT imaging findings into acute necrotic collection, psuedocyst, acute necrotic collection and walled of necrosis. Organ failure will be assessed according to modified marshal scoring system into transient or persistent organ failure.
Methodology: We will be carrying forward our study on Siemens 16 slice computer tomography machine over a sample of 140 patients coming to the outpatient department of our hospital which will be followed by a routine clinical follow up of the patient to find out their prognosis.
Results: Will be tabulated at the end of the study using SPSS version 26 software.
Conclusion: The revised Atlanta classification for acute pancreatitis, in conjunction with the Modified Marshall Scoring System for organ failure, if found useful, in our series in improving the prognosis of the patients, then it can be incorporated in management.
Classical and Advanced Imaging for the Characterization of Pyrrolidone‐ and Caprolactam‐Based Materials
Authors: Puccetti Germain 
Published: June 2021

Abstract
Image analysis performs the quantitative extraction of information from the captured image by means of dedicated software taking into account spatial and spectral calibrations. This chapter provides the reader an overview of the most important types of imaging approaches and the nature of the information obtained. The optical imaging techniques will be separated by their information content, with the main types being classical reflectance imaging, fluorescence imaging, time‐resolved imaging, hyperspectral imaging, confocal imaging, and interferometric imaging. The chapter explores in more detail the macroscopic and microscopic imaging approaches used in the characterization of pyrrolidone‐ and caprolactam‐based materials. Seven main fields of application have a long history of using pyrrolidone‐based compounds: printing, medical applications, bio‐materials, antibacterial films and coatings, filtration, energy and electronic applications, and personal care/home care. Polymers help in the care of the surfaces and their protection against attacks of sugars and acids.
Pyrrolidone and Caprolactam‐Based Materials in Active Pharmaceutical Ingredient (API) Applications
Authors: Hood David K. , Ananthraman Srinivasan , Musa Osama M. 
Published: June 2021

AbstractActive pharmaceutical ingredients (APIs) are the essential, active ingredients of pharmaceutical dosage forms and drug delivery systems. This chapter provides a comprehensive and systematic coverage of pharmaceutical and biomedical applications of pyrrolidone and caprolactam‐based materials in API applications. Antibiotics and antimicrobials are indispensable drugs for human and animal health and well‐being. The chapter also provides an explanation of the mechanism of action for the excipients in dosage forms ranging from conventional solids and liquids to novel solids and colloidal drug delivery systems. The modulation of solubility of poorly soluble drugs is a viable and safe approach for enhancing the drug's bioavailability. The drug development within the pharmaceutical industry has undergone a significant transformation. Prior to the late 1980s, drug candidates were primarily established by empirically‐based screening programs, where the leading candidates were mostly selected from chemical compounds that had already undergone significant technical investigation.
Safety and Toxicology of Caprolactams and Caprolactam‐Based Polymers
Authors: Kim Sang‐Tae , Schatz Anthony , Choi Christopher 
Published: June 2021

AbstractToxicology is more precisely the study of adverse effects on living organisms from exposure to chemicals, drugs, or biological agents. Acute toxicity describes the adverse effects arising from a single or short‐term exposure to a chemical. Quantitative structure activity relationships in silico toxicology is one type of toxicity assessment that uses computational methods to analyze, simulate, visualize, or predict the toxicity of chemicals. The chapter aims to evaluate the toxicity of caprolactam chemistries including monomer and polymer molecules. The toxicity of caprolactam and vinylcaprolactam has been summarized by numerous human health and environmental agencies worldwide. Caprolactam and vinylcaprolactam are high production lactams of aminocaproic acid. Caprolactam was tested in the NTP Carcinogenesis Testing Program using rats and mice. In humans, irritation of the skin and the mucous membranes were reported for caprolactam. Acute exposure to caprolactams may result in irritation and burning of the eyes, nose, throat, and skin in humans.
Pyrrolidone and Caprolactam‐Based Materials in Adhesion Related Applications
Authors: Hood David K. , Ananthraman Srinivasan , Musa Osama M. 
Published: June 2021

AbstractAdhesion is the process of attachment of substances due to the presence of intermolecular forces of attraction between them. Polyvinyl pyrrolidone (PVP) polymers have widespread use in the adhesive industry because of their favorable physicochemical properties. In an aqueous environment, the adhesive properties of pyrrolidone‐based materials are correlated to their polarities. Pressure sensitive adhesives (PSA) are an unusual class of adhesive polymers. A PSA composition should also exhibit high‐cohesive strength and elasticity. Lactam‐based vinyl monomers are widely employed in ultraviolet and electron beam curable adhesives commonly found in coatings, inks, optical materials, and packaging applications. Urea‐formaldehyde thermoset resins are one of the most important classes of adhesive resins for producing wood‐based panels. The adhesives were made by coaxial‐electrospinning of polycaprolactam as the core and PVP as the adhesive sheath. The resulting material was radiation‐crosslinked to yield matrices that were composed of fibrous layered materials.
The World Trade Center Health Program: Petitions for adding qualifying health conditions
Authors: Daniels Robert D. , Carreón Tania , Bilics Jessica A. , Reissman Dori B. , Howard John 
Published: June 2021

AbstractThe federally mandated World Trade Center Health Program provides limited health benefits for qualifying health conditions related to the 9/11 terrorist attacks. A qualifying health condition is an illness or health condition for which the member's exposure to airborne toxins, any other hazard, or any other adverse condition resulting from the 9/11 terrorist attacks is considered substantially likely to be a significant factor in aggravating, contributing to, or causing the illness or health condition. These qualifying health conditions are listed in federal regulations. The regulations also provide a process for amending this list. This commentary describes the methods developed for adding health conditions to the list of qualifying health conditions and discusses changes to the list that have occurred during the Program's 2011–2020 period.