bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self‐Healing Titanium Dioxide Nanocapsules‐Graphene/Multi‐Branched Polyurethane Hybrid Flexible Film with Multifunctional Properties toward Wearable Electronics
Authors: Zhou Jianlin , Liu Han , Sun Yangyi , Wang Chaoxia , Chen Kunlin 
Published: May 2021

AbstractThe integration of self‐healing capabilities into flexible electronics arouses extensive attention. The application of self‐healing electronics with multifunctional properties in a variety of exceptional environments has been identified to be significantly challenging and not yet proven to be fully viable thus far. In the present study, the self‐healing octadecane loaded titanium dioxide nanocapsules (OTNs)‐graphene/multi‐branched polyurethane (PU) hybrid flexible multifunctional film is successfully prepared. The prepared film exhibits a novel self‐repair capability that consists of disulfide bonds in the leading chains for efficient self‐healing of PU damage, as well as multiple amino groups in the branches for damage between OTNs‐graphene and PU. Impacted by the constructed self‐healing system and well‐dispersed OTNs‐graphene, the prepared flexible film demonstrates a prominent performance in piezoresistive sensing and a desirable outcome of ultraviolet protection properties, which can effectively prolong its service life, especially when used outdoors. Moreover, the film exhibits thermal insulating properties, capable of offering a suitable route for thermal protection of bio‐integrated wearable electronic devices system. Thus, this self‐healing multifunctional film is promising in wearable electronics, human–machine interaction, artificial intelligence devices, etc.
Stretchable and Self‐Healable Organohydrogel as Electronic Skin with Low‐Temperature Tolerance and Multiple Stimuli Responsiveness
Authors: Liang Yongzhi , Liang Haiyi 
Published: May 2021

AbstractThe design and fabrication of electronic skin that mimics the human somatosensory system has attracted a great deal of attention. However, existing materials could hardly achieve the unique characteristics that natural skin possesses, including excellent mechanical flexibility, self‐healing ability, the sensory ability of tension, pressure, temperature, humidity, and the ability to secrete sweat through various sensory receptors and nervous pathways. In this paper, a new type of stretchable (over 2150%), tough (over 4 MJ m−3), conductive (up to 1.68 S m−1), and self‐healable (self‐healing efficiency up to 100%) organohydrogel with low‐temperature tolerance (stretchable below −50 °C) and multiple stimuli responsiveness is prepared by a simple “one‐pot” strategy at room temperature. The synthesized electronic skin with this organohydrogel can detect slight changes in tension, pressure, temperature, and humidity, and even distinguish between saline and alkaline solutions, showing high sensitivity in the broad strain window. This organohydrogel also has application prospects in humanoid robotics, flexible energy storage technologies, and health‐monitoring devices.
Aqueous Rechargeable Multivalent Metal‐Ion Batteries: Advances and Challenges
Authors: Pan Zhenghui , Liu Ximeng , Yang Jie , Li Xin , Liu Zhaolin , Loh Xian Jun , Wang John 
Published: May 2021

AbstractAqueous rechargeable multivalent metal‐ion batteries (ARMMBs) have a great potential to meet the future demands in the wide spectrum of energy storage applications, ranging from wearables/portables to large‐scale stationary energy storage. This is owing to the abundance of the electrode materials, their eco‐friendliness, high safety, fast‐charging capability, high power density, and long‐cycling capability. There has been considerable progress in ARMMBs over the past ten years. However, their rather narrow operating voltage window and insufficient energy density are still the main barriers to their use as alternative power sources to replace the widely used lithium‐ion batteries. In this overview, the key advantages and current challenges for ARMMBs with respect to the cathode materials, electrolytes, metal anodes, and their integrations into full cells are first examined. The recent approaches in addressing these key challenges are then looked into, focusing on the new designs of advanced electrode materials, electrolytes, and also their interfaces. Finally, perspectives on the near‐future development of ARMMBs are presented, together with a brief roadmap, where one of main pursuits will be to translate ARMMBs from current laboratory prototypes to commercialization/industrialization.
FRET‐Integrated Polymer Brushes for Spatially Resolved Sensing of Changes in Polymer Conformation
Authors: Besford Quinn A. , Yong Huaisong , Merlitz Holger , Christofferson Andrew J. , Sommer Jens‐Uwe , Uhlmann Petra , Fery Andreas 
Published: May 2021

AbstractPolymer brush surfaces that alter their physical properties in response to chemical stimuli have the capacity to be used as new surface‐based sensing materials. For such surfaces, detecting the polymer conformation is key to their sensing capabilities. Herein, we report on FRET‐integrated ultrathin (<70 nm) polymer brush surfaces that exhibit stimuli‐dependent FRET with changing brush conformation. Poly(N‐isopropylacrylamide) polymers were chosen due their exceptional sensitivity to liquid mixture compositions and their ability to be assembled into well‐defined polymer brushes. The brush transitions were used to optically sense changes in liquid mixture compositions with high spatial resolution (tens of micrometers), where the FRET coupling allowed for noninvasive observation of brush transitions around complex interfaces with real‐time sensing of the liquid environment. Our methods have the potential to be leveraged towards greater surface‐based sensing capabilities at intricate interfaces.
Synthesis of a Boron–Imidazolate Framework Nanosheet with Dimer Copper Units for CO2 Electroreduction to Ethylene
Authors: Shao Ping , Zhou Wei , Hong Qin‐Long , Yi Luocai , Zheng Lirong , Wang Wenjing , Zhang Hai‐Xia , Zhang Huabin , Zhang Jian 
Published: May 2021

AbstractFundamental understanding of the dependence between the structure and composition on the electrochemical CO2 reduction reaction (CO2RR) would guide the rational design of highly efficient and selective electrocatalysts. A major impediment to the deep reduction CO2 to multi‐carbon products is the complexity of carbon–carbon bond coupling. The chemically well‐defined catalysts with atomically dispersed dual‐metal sites are required for these C−C coupling involved processes. Here, we developed a catalyst (BIF‐102NSs) that features Cl− bridged dimer copper (Cu2) units, which delivers high catalytic activity and selectivity for C2H4. Mechanistic investigation verifies that neighboring Cu monomers not only perform as regulator for varying the reaction barrier, but also afford distinct reaction paths compared with isolated monomers, resulting in greatly improved electroreduction performance for CO2.
Security and privacy with opacity‐based state observation for finite state machine
Authors: Zhang Zhipeng , Xia Chengyi , Chen Shengyong 
Published: May 2021

AbstractTopics on security and privacy are very fundamental and important in the Internet of Things (IoT). In this paper, we explore the impact of state observation on the opacity of IoT, which is modeled by Moore‐type finite state machine. Firstly, to characterize the intrusion estimator under the event‐state observation, a multi‐linear algebraic expression is proposed through the Boolean semi‐tensor product (STP), and on the basis of the novel representation, the validation criterion is given by some matrix manipulations. Subsequently, considering that the input information may not be measured due to the physical shielding of the system against external intruders, we continue to discuss the opacity with state observation by a permutation structure matrix. Meanwhile, the verification of opacity with event‐state observation is generalized to the one with only state observation. Finally, we offer an example to illustrate the effectiveness of the newly proposed method. Taken together, the current results are helpful to provide a novel theoretical approach for investigating the privacy‐preserving problem in the area of IoT and complex cyber‐physical networks.
MiR‐3130‐5p is an intermediate modulator of 2q33 and influences the invasiveness of lung adenocarcinoma by targeting NDUFS1
Authors: Zhan Juan , Sun Shenghua , Chen Yixing , Xu Chaoqun , Chen Qinwei , Li Minjie , Pei Yihua , Li Qiyuan 
Published: May 2021

AbstractGenome‐wide association studies (GWAS) have reported a handful of loci associated with lung cancer risk, of which the pathogenic pathways are largely unknown. We performed cis‐expression quantitative trait loci (eQTL) mapping for 376 lung cancer related GWAS loci in 227 TCGA lung adenocarcinoma (LUAD) and reported two risk loci as eQTL of miRNA. Among the miRNAs in association with lung cancer risk, we further predicted and validated miR‐3130‐5p as an intermediate modulator of risk loci 2q33 and the tumor suppressor NDUFS1. We assessed the phenotypic impacts of the interaction between miR‐3130‐5p and NDUFS1 in both lung cancer cell lines and mice xenograft models. As a result, miR‐3130‐5p directly regulates the expression of NDUFS1 and the corresponding tumor invasiveness, migration and epithelial‐mesenchymal transition (EMT). Our findings provide important clues for the pathogenic mechanism of 2q33 in lung carcinogenesis which informs clinical diagnosis and prognosis of LUAD.We performed a cis‐eQTL analysis for 376 lung cancer risk loci based on the expression profiles of 251 miRNAs in a cohort of 227 TCGA lung adenocarcinoma. We report a novel pathogenic pathway of 2q33 via miR‐3130‐5p and NDUFS1.
Influence of parents, peers, and media on adolescents' consumer knowledge, attitudes, and purchase behavior: A meta‐analysis
Authors: Mishra Anubhav , Maity Moutusy 
Published: May 2021

AbstractAdolescents are considered a critical consumer segment due to their huge spending power and significant influence in family purchase decisions. Parents, peers, and media are the three essential socialization agents that significantly influence adolescents' consumer knowledge (awareness), attitudes (attitude toward ad, brand, and price), and purchase behavior via the process of consumer socialization. This meta‐analysis investigates the impact of these agents by integrating findings from 36 studies, including 194 relationships among 29,209 adolescent respondents. The study examines the moderating role of various cultural dimensions (individualistic, power distance, and masculinity), publication year, and age. The findings reveal that peers have the maximum number of significant effects, followed by media and parents. Parents and peers have a stronger impact on adolescents' attitudes toward brand in cultures that are high in individualism and power distance. The effects for many focal relationships are stronger in recent publications, which confirms the critical influence of the external environment, including access to the Internet and social media. Age, culture, and publication year moderate key relationships. The study contributes to consumer socialization literature and has practical implications for marketers interested in teenage consumers.
Dental stem cell banking: Techniques and protocols
Authors: Khaseb Sanaz , Orooji Mahdi , Pour Majid Ghasemian , Safavi Seyed Mohammadreza , Eghbal Mohammad Jafar , Rezai Rad Maryam 
Published: May 2021

AbstractDental tissue‐derived stem cells (DSCs) provide an easy, accessible, relatively noninvasive promising source of adult stem cells (ASCs), which brought encouraging prospective for their clinical applications. DSCs provide a perfect opportunity to apply for a patient's own ASC, which poses a low risk of immune rejection. However, problems associated with the long‐term culture of stem cells, including loss of proliferation and differentiation capacities, senescence, genetic instability, and the possibility of microbial contamination, make cell banking necessary. With the rapid development of advanced cryopreservation technology, various international DSC banks have been established for both research and clinical applications around the world. However, few studies have been published that provide step‐by‐step guidance on DSCs isolation and banking methods. The purpose of this review is to present protocols and technical details for all steps of cryopreserved DSCs, from donor selection, isolation, cryopreservation, to characterization and quality control. Here, the emphasis is on presenting practical principles in accordance with the available valid guidelines.
Electrochemical Reduction of Carbon Dioxide on 3D Printed Electrodes
Authors: Vaněčková Eva , Bouša Milan , Shestivska Violetta , Kubišta Jiří , Moreno‐García Pavel , Broekmann Peter , Rahaman Motiar , Zlámal Martin , Heyda Jan , Bernauer Milan , Sebechlebská Táňa , Kolivoška Viliam 
Published: May 2021

AbstractRising levels of atmospheric carbon dioxide (CO2) intensify global warming. Electrochemical reduction of CO2 allows its conversion into value‐added chemicals. This work presents the first application of 3D printing to manufacture catalysts for this process. Carbon nanotube‐based electrodes printed by fused deposition modeling were functionalized by copper electroplating. The combination of scanning electron microscopy and electrochemical characterization revealed that the electroplating leads to randomly positioned hemispherical copper microparticles with charge transfer characteristics approaching those of planar interfaces. The activity of catalysts was inspected in the saturated solution of CO2 in aqueous KHCO3 electrolyte by monitoring the concentration of formate (HCOO−) as one of reaction products. The Faradaic efficiency vs. electrode potential dependence found in this work is comparable to characteristics reported for conventionally prepared micro‐structured copper catalysts. Procedures devised and implemented in this work pave the way for the development of 3D printed electrocatalysts with controlled micro‐architecture, activity and product selectivity.
Silver(I)‐N‐heterocyclic carbene complexes challenge cancer; evaluation of their anticancer properties and in silico studies
Authors: Şahin‐Bölükbaşı Serap , Cantürk‐Kılıçkaya Pakize , Kılıçkaya Ozan 
Published: May 2021

AbstractBecause of the continuous need for efficient therapeutic agents against various kinds of cancers and infectious diseases, the pharmaceutical industry has to find new candidates and strategies to develop novel and efficient drugs. They increasingly use computational tools in R&D stages for screening extensive sets of drug candidates before starting pre‐clinical and clinical trials. N‐Heterocyclic carbenes (NHCs) can be evaluated as good drug candidates because they offer both anti‐cancer and anti‐inflammatory features with their general low‐toxicity profiles. To date, different kinds of NHCs (Cu, Co, Ni, Au, Ag, Ru, etc.) have been synthesized and their therapeutic uses has been shown. Here, we have reviewed the recent studies focused on Ag(I)‐NHC complexes and their anti‐cancer activities. Also, existing examples of the usage of density functional theory and structure–activity relationship have been evaluated.
MultiGWAS: An integrative tool for Genome Wide Association Studies in tetraploid organisms
Authors: Garreta Luis , Cerón‐Souza Ivania , Palacio Manfred Ricardo , Reyes‐Herrera Paula H. 
Published: May 2021

AbstractThe genome‐wide association studies (GWASs) are essential to determine the genetic bases of either ecological or economic phenotypic variation across individuals within populations of the model and nonmodel organisms. For this research question, the GWAS replication testing different parameters and models to validate the results' reproducibility is common. However, straightforward methodologies that manage both replication and tetraploid data are still missing. To solve this problem, we designed the MultiGWAS, a tool that does GWAS for diploid and tetraploid organisms by executing in parallel four software packages, two designed for polyploid data (GWASpoly and SHEsis) and two designed for diploid data (GAPIT and TASSEL). MultiGWAS has several advantages. It runs either in the command line or in a graphical interface; it manages different genotype formats, including VCF. Moreover, it allows control for population structure, relatedness, and several quality control checks on genotype data. Besides, MultiGWAS can test for additive and dominant gene action models, and, through a proprietary scoring function, select the best model to report its associations. Finally, it generates several reports that facilitate identifying false associations from both the significant and the best‐ranked association Single Nucleotide Polymorphisms (SNPs) among the four software packages. We tested MultiGWAS with public tetraploid potato data for tuber shape and several simulated data under both additive and dominant models. These tests demonstrated that MultiGWAS is better at detecting reliable associations than using each of the four software packages individually. Moreover, the parallel analysis of polyploid and diploid software that only offers MultiGWAS demonstrates its utility in understanding the best genetic model behind the SNP association in tetraploid organisms. Therefore, MultiGWAS probed to be an excellent alternative for wrapping GWAS replication in diploid and tetraploid organisms in a single analysis environment.
New Magnetic and Luminescent Dy(III) and Dy(III)/Y(III) Based Tetranuclear Silsesquioxane Cages
Authors: Kulakova Alena N. , Nigoghossian Karina , Félix Gautier , Khrustalev Victor N. , Shubina Elena S. , Long Jérôme , Guari Yannick , Carlos Luis D. , Bilyachenko Alexey N. , Larionova Joulia 
Published: May 2021

AbstractWe report here the synthesis, structure, luminescence, and magnetic properties of three new cage‐like tetranuclear silsesquioxanes (Et4N)2[(PhSiO1..5)8(Y0.75Dy0.25O1.5)4(O)(NO2.5)6(EtOH)2(MeCN)2] and (Cat)2[(PhSiO1.5)8(DyO1.5)4(O)(NO2.5)6(EtOH)2(MeCN)2] (Cat=Et4N or Ph4P). They present a characteristic green‐yellow emission. The Y3+/Dy3+ compound displays in addition a field‐induced Single Molecule Magnet (SMM) behavior making it the first reported bifunctional magneto‐luminescent silsesquioxane.
Cross-Ecosystem Fluxes of Pesticides from Prairie Wetlands Mediated by Aquatic Insect Emergence: Implications for Terrestrial Insectivores
Authors: Kraus Johanna M. , Kuivila Kathryn M. , Hladik Michelle L. , Shook Neil , Mushet David M. , Dowdy Kelen , Harrington Rachel 
Published: May 2021

Abstract
Contaminants alter the quantity and quality of insect prey available to terrestrial insectivores. In agricultural regions, the quantity of aquatic insects emerging from freshwaters can be impacted by insecticides originating from surrounding croplands. We hypothesized that, in such regions, adult aquatic insects could also act as vectors of pesticide transfer to terrestrial food webs. To estimate insect-mediated pesticide flux from wetlands embedded in an important agricultural landscape, semipermanetly and temporarily ponded wetlands were surveyed in cropland and grassland landscapes across a natural salinity gradient in the Prairie Pothole Region of North Dakota (USA) during the bird breeding season in 2015 and 2016 (n = 14 and 15 wetlands, respectively). Current-use pesticides, including the herbicide atrazine and the insecticides bifenthrin and imidacloprid, were detected in newly emerged insects. Pesticide detections were similar in insects emerging from agricultural and grassland wetlands. Biomass of emerging aquatic insects decreased 43%, and insect-mediated pesticide flux increased 50% along the observed gradient in concentrations of insecticides in emerging aquatic insects (from 3 to 577 ng total insecticide g–1 insect). Overall, adult aquatic insects were estimated to transfer between 2 and 180 µg total pesticide wetland–1 d–1 to the terrestrial ecosystem. In one of the 2 study years, biomass of emerging adult aquatic insects was also 73% lower from agricultural than grassland wetlands and was dependent on salinity. Our results suggest that accumulated insecticides reduce the availability of adult aquatic insect prey for insectivores and potentially increase insectivore exposure to insect-borne pesticides. Adult aquatic insects retain pesticides across metamorphosis and may expose insectivores living near both agricultural and grassland wetlands to dietary sources of toxic chemicals. Environ Toxicol Chem 2021;40:2282–2296. Published 2021. This article is a U.S. Government work and is in the public domain in the USA.
Abstract
Development of a novel hybrid cognitive model validation framework for implementation under COVID‐19 restrictions
Authors: Stone Paul B. , Nelson Hailey Marie , Fendley Mary E. , Ganapathy Subhashini 
Published: May 2021

AbstractThe purpose of this study was to develop a method for validation of cognitive models consistent with the remote working situation arising from COVID‐19 restrictions in place in Spring 2020. We propose a framework for structuring validation tasks and applying a scoring system to determine initial model validity. We infer an objective validity level for cognitive models requiring no in‐person observations, and minimal reliance on remote usability and observational studies. This approach has been derived from the necessity of the COVID‐19 response, however, we believe this approach can lower costs and reduce timelines to initial validation in post‐Covid‐19 studies, enabling faster progress in the development of cognitive engineering systems. A three‐stage hybrid validation framework was developed based on existing validation methods and was adapted to enable compliance with the specific limitations derived from COVID‐19 response restrictions. This validation method includes elements of argument‐based validation combined with a cognitive walkthrough analysis, and reflexivity assessments. We conducted a case study of the proposed framework on a developmental cognitive model of cardiovascular surgery to demonstrate application of a real‐world validation task. This framework can be easily and quickly implemented by a small research team and provides a structured validation method to increase confidence in assumptions as well as to provide evidence to support validity claims in the early stages of model development.
A heuristic international glimpse at SARS‐CoV‐2 effects on work‐home equilibrium and women
Authors: Gulotta Crystal J. , Madeira‐Revell Kirsten , Fendley Mary E. 
Published: May 2021

AbstractThis article takes a condensed look at the impact that SARS‐CoV‐2 has had on the work‐life balance of women engineers across the world in industry, military and academia. The same impact has been felt by all women, not only in science, as it is this gender status that inevitably ties women together, facing the same challenges, and cannot be separated by category of employment, or lack thereof. Studies from around the world give us insight into how the pandemic has instigated changes and influenced choices made between work and domestic demands. Globally, women are burdened with challenges that may compromise their progression in male‐dominated fields, such as engineering. Taking a glimpse at this issue for women through an international lens, we identify potential human factors methods to respond to this global problem, offering tools and forewarnings for improving our efforts in designing for, and maintaining equilibrium for women in engineering, technology, academia, and beyond.