bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of brainstem auditory evoked response and biochemical markers in patients of alcohol use disorder
Authors: Siddiqui Mudassir Anis , Srivastava Divya , Choudhary Sandeep 
Published: December 2021

Objectives:
Data available on brainstem auditory evoked response (BAER) and its correlation with biochemical parameters in patients of alcohol use disorder (AUD) in Indian population is scanty. Therefore, this study was undertaken to focus on the effects of AUD on BAER and liver enzymes.

Materials and Methods:
This case-control study included 40 males in the study group who had AUD and 40 healthy males in the control group in the age group of 20–60 years. The BAER was performed using octopus NCS/ EMG/EP (Clarity) machine. The levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase and serum bilirubin were estimated in all the subjects.

Results:
We observed a highly significant increase in the absolute latencies of waves III and V and interpeak latencies (IPL) I-III and I-V of BAER in the patients of AUD in this study. Significant increase in the liver enzymes and especially AST/ALT ratio of patients of AUD was seen which indicated towards subclinical alcoholic hepatitis. The latencies of waves of EPs (waves III, V, IPL I-III and IPL I-V) were positively correlated with the biochemical parameters and duration of AUD.

Conclusion:
Our findings indicated that AUD lead to the increase in brainstem transmission time and also lead to subclinical alcoholic hepatitis which is reflected by the increase in the liver enzymes. We concluded that chronic alcohol consumption affected the auditory pathways and delayed the auditory transmission time which was suggestive of possible demyelination of auditory tracts.
Perivascular histamine receptors mediate vasosensory reflex responses elicited by thermal nociceptive stimuli in anaesthetised rat models
Authors: Revand Ravindran , Singh Sanjeev K. 
Published: December 2021

Objectives:
Reflex responses elicited by intra-arterial (i.a) instillation of nociceptive agents are known as vasosensory reflex responses. The present study was designed to demonstrate the vasosensory reflex responses evoked by thermal nociceptive stimuli in anaesthetised rat models and to examine the role of perivascular histamine receptors in mediating these responses.

Materials and Methods:
In this study, saline at different temperatures (0°C/30°C/55°C) was instilled retrogradely into the femoral artery to stimulate the perivascular nociceptive terminals and the respiratory movements, BP and ECG were recorded for 10 min. Experiments were performed in four groups of rats. Two groups were dedicated to study the temperature-induced reflex cardiorespiratory (CVR) responses after i.a instillation of cold (0°C) and warm saline (55°C). The responses in these groups were compared with the responses after instillation of normal saline at room temperature (30°C) in a separate group of rats that served as time matched control group. Another group of rats was pre-treated with pheniramine and the responses elicited by warm saline were studied.

Results:
Instillation of warm saline produced immediate (2–6 s) hyperventilatory, hypotensive and bradycardiac responses which were short-lived, while equivolume of normal saline at room temperature did not. Cold saline also elicited the CVR changes of similar quality as that of warm saline but of lesser quantity which were not significantly different from the control group. Pre-treatment with pheniramine significantly attenuated the warm saline-induced reflex responses.

Conclusion:
Activation of perivascular sensory nerve terminals by thermal nociceptive stimuli elicits vasosensory reflex responses altering CVR parameters. Perivascular histamine receptors play a significant role in mediating the temperature-induced vasosensory reflex responses.
Holocord spontaneous pneumorrhachis in the setting of refractory emesis
Authors: Houston Rebecca , Fiani Brian , Musch Brian , Tayag Emilio 
Published: December 2021

Background:
Pneumorrhachis (PNR) is the presence of air within the spinal canal and may be either intramedullary or extramedullary in location. The etiology is most commonly iatrogenic or traumatic in nature. Treatment is dependent on underlying cause and physical exam.

Case Description:
Herein, we describe the second case in the literature of spontaneous holocord PNR in a young patient without risk factors. A 22-year-old male with no past medical history presented to the hospital for 2 days of vomiting and cramping in his hands and feet secondary to severe dehydration. He recently started a new job as a manual laborer and had to leave work early 2 days prior due to overexertion working outside in heat ranging from 100 to 120 degrees Fahrenheit. CT abdomen and pelvis demonstrated spontaneous pneumomediastinum and extramedullary PNR extending upward from L3 throughout the thoracic spine to the upper limit of the scan. Subsequent CT cervical and thoracic spine showed the full length of the extradural air from C2-T12 and again at L3.

Conclusion:
Spontaneous PNR is an uncommon, typically self-limited condition in which air is introduced into the spinal axis. Anatomic predisposition makes the extradural, dorsal cord in the cervicothoracic region the most common location. Patients are rarely symptomatic, and treatment is supportive in nature once secondary causes with high rates of morbidity and mortality are ruled out.
Pediatric brain abscess – etiology, management challenges and outcome in Lagos Nigeria
Authors: Kanu Okezie Obasi , Ojo Omotayo , Esezobor Christopher , Bankole Olufemi , Olatosi John , Ogunleye Ezekiel , Asoegwu Chinyere , Eghosa Morgan , Adebayo Bamidele , Oladele Rita , Nwawolo Clement 
Published: December 2021

Background:Brain abscess in children is a neurosurgical emergency with potentially catastrophic outcome despite the advances made in neuroimaging techniques and antibiotic therapy. Symptoms are nonspecific and may vary with the child’s age, location, size, numbers and stage of abscess, and the primary source of infection. Treatment is usually with broad-spectrum antibiotics in combination and surgical evacuation in most cases or antibiotics alone in selected cases with clear-cut indications. This study was to document clinical characteristics, etiological factors, and spectrum of bacteriologic agents responsible for pediatric brain abscess in an African city, the challenges and management outcome over the study period.Methods:This was a retrospective study over an 11-year period involving 89 children who presented with brain abscess. Information of interest was extracted from the medical records of each participant. The results from data analysis were presented in charts and tables.Results:Eighty-nine children aged 0.85–15.7 years (median age of 6.4 years) met the inclusion criteria. The male-to-female ratio was 1.8:1. Headache (80%), fever (78%), and hemiparesis (78%) were the most common symptoms. Brain imaging deployed was CT scan in 56 (63%), MRI in 9 (10%), and transfontanel ultrasound scan in 24 (27%) children. Seventy-one (80%) children had antibiotics with surgical evacuation while 18 (20%) children received only antibiotics. In 19 (27%) children, the culture of the abscess was negative. In 53 (75%) children, Gram-positive aerobic organisms were isolated. A total of 75 patients (84%) had a favorable outcome.Conclusion:Pediatric brain abscess still poses significant public health challenge, especially in resource-limited regions. Successful management of brain abscess requires high index of suspicion for early diagnosis, referral, and intervention.
Esthesioneuroblastoma with recurrent dural metastases: Long-term multimodality treatment and considerations
Authors: Deng Hansen , McDowell Michael M. , Gersey Zachary C. , Abou-Al-Shaar Hussam , Snyderman Carl H. , Zenonos Georgios A. , Lunsford L. Dade , Gardner Paul A. 
Published: December 2021

Background:
Esthesioneuroblastoma (ENB) is a rare malignant disease and treatment protocols have not been standardized, varying widely by disease course and institutional practices. Management typically includes wide local excision through open or endoscopic resection, followed by radiotherapy, chemotherapy, and stereotactic radiosurgery. Tumor control can differ on a case-by-case basis. Herein, the complex management of a rare case of recurrent disease with multiple dural metastases is presented.

Case Description:
A 60-year-old patient was diagnosed with ENB after presenting with anosmia and epistaxis. The patient underwent combined endonasal and transfrontal sinus craniofacial resection, followed by proton beam radiation therapy and chemotherapy. Subsequently, he developed a total of 25 dural metastases that were controlled with repeated Gamma Knife Radiosurgery (GKRS). In spite of post-treatment course that was complicated by radiation necrosis and local vasculopathy, the patient made significant recovery to functional baseline.

Conclusion:
The management of ENB entails multimodality and multidisciplinary care, which can help patients obtain disease control and long-term survival. Recurrent ENB dural metastases can behave as oligometastatic disease manageable with aggressive focal GKRS. As prognosis continues to improve, chronic treatment effects of radiation in such cases should be taken into consideration.
Should the direct aspiration first pass technique be advocated over the stent-retriever technique for acute ischemic stroke? A systematic review and meta-analysis of 7692 patients
Authors: Negida Ahmed , Ghaith Hazem S. , Gabra Mohamed Diaa , Aziz Mohamed Abdelalem , Elfil Mohamed , Al-Shami Haider , Bahbah Eshak I. , Kanmounye Ulrick Sidney , Esene Ignatius , Raslan Ahmed M. 
Published: December 2021

Background:The present meta-analysis aimed to synthesize evidence from all published studies with head-to-head data on the outcomes of a direct aspiration first pass technique (ADAPT) and the stent-retriever (SR) in acute ischemic stroke (AIS) patients.Methods:We searched PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials from inception to March 2021 for relevant clinical trials and observational studies. Eligible studies were identified, and all relevant outcomes were pooled in the meta-analysis random-effects model of DerSimonian-Laird.Results:Thirty studies were included in the meta-analysis with a total of 7868 patients. Compared with the SR, the ADAPT provides slightly higher rates of successful recanalization (RR 1.06, 95% CI [1.02 to 1.10]) and complete recanalization (RR 1.20, 95% CI [1.01 to 1.43]) but with more need for rescue therapy (RR 1.81, 95% CI [1.29 to 2.54]). There were no significant differences between the two techniques in terms of mortality at discharge, mortality at 90 days, change in the National Institutes of Health Stroke Scale score, the favorable outcome (modified Rankin scale (mRS) of 0-2), time to the groin puncture, or frequency of complications as intracerebral hemorrhage (ICH), symptomatic intracranial hemorrhage (sICH), embolus in a new territory (ENT), hemorrhagic infarction, parenchymal hematoma, subarachnoid hemorrhage, or procedural complications (allP> 0.05).Conclusion:Current evidence supports the use of the ADAPT technique to achieve successful and complete recanalization while considering the higher need for rescue therapy in some patients.
The Delang Isolect: A Synchronic Description on Its Phonemic System, Retention, and Innovation
Authors: Budhiono Ralph Hery 
Published: December 2021

Problem to be discussed in the research is how does the phonemic system of the Delang and its retention and innovation to be compared with its proto Austronesia (PAN). This research is aimed to identify the character of the Delang descriptively, out from its status either as an independent language or just a dialect or subdialect of a certain language. The research hopefully can give more knowledge contributions especially for the speaker and the community at large. This is a descriptive research with synchronic-qualitative approach. The data will be 200 basic lexicons from Swadesh that is compiled by the language mapping team of Balai Bahasa Kalimantan Tengah in 2019. The analysis is started from the description of the Delang phonemic system. The phonemic retention and innovation come from comparing the lexicons with its Blust ‘s PAN. Based on the analysis the writer underlined some conclusions. The isolect has 5 vowels and 18 consonants. Some protophonemes, like *a and *u in certain positions, are maintained, while some other phonemes are innovated or substituted. Some secondary innovations found, namely prothesis, syncope, metathesis, aphaeresis, and fortition.AbstrakPenelitian ini bertujuan untuk mengidentifikasi isolek Delang secara lebih mendalam, terlepas dari statusnya sebagai bahasa mandiri atau dialek dari bahasa lain. Penelitian ini diharapkan dapat memberikan pengetahuan kepada penutur isolek Delang khususnya dan masyarakat pada umumnya terkait dengan sistem, pemertahanan, dan inovasi fonemik dalam isolek itu. Metode yang digunakan dalam penelitian ini ialah deskriptif dengan pendekatan sinkronis-kualitatif. Data yang merupakan 200 kata dasar Swadesh dikumpulkan tahun 2019 oleh tim pemetaan Balai Bahasa Kalimantan Tengah dan berupa data mentah yang belum ditranskripsikan. Analisis dimulai dari deskripsi sistem fonemis isolek itu. Retensi dan inovasi fonemik didapatkan dari perbandingan antara 200 kosakata dasar isolek itu dan PAN versi Blust. Berdasarkan analisis diperoleh beberapa simpulan. Isolek Delang memiliki 5 vokal dan 18 konsonan. Beberapa fonem proto, seperti *a dan *u, pada posisi tertentu dipertahankan, sedangkan fonem lain diinovasikan atau diubah. Inovasi sekunder yang didapatkan ialah protesis, sinkope, metatesis, afaeresis, dan fortisi.
Development of Cloud-Based Co-Parenting Strengthening System
Authors: Engel Mychael Maoeretz , Setiawan Jenny Lukito , Indriati Lisa 
Published: December 2021

Co-parenting emphasizes how couple manage their relationship in the parenting domains and carry out their role as parents. Based on research conducted by Feinberg and colleagues (2012), there are four overlapping domains of co-parenting: (1) child rearing agreement; (2) support/undermining partner’s parenting; (3) joint family management; and (4) division of labor. The interference of mobile-based technology is needed on the co-parenting relationship between the couple with reference to the four domains of co-parenting. The method used was the Systems Development Life Cycle (SDLC) model. It was divided into six stages of the process: requirement analysis, system design, implementation, system testing, system deployment, and system maintenance. In implementation, the system at an early stage has four main features: (1) child’s activity scheduling and reminder; (2) co-parenting’s education contents; (3) partner’s feedback; and (4) co-parenting’s assessment. The results that are proven by experts, agreed that educational content in the application is very necessary for more knowledge for parents, UI/UX design that is friendly and easy to understand by users, as well as the use of the latest reliable and flexible technology.
Penerapan Model Flipped Classroom Berbantuan Kahoot dalam Meningkatkan Keterampilan Menulis Teks Eksposisi
Authors: Anggraeni Rosita Dwi , Khaerunnisa Khaerunnisa 
Published: December 2021

Penelitian mengenai penerapan model pembelajaran flipped classroom berbantuan kahoot dalam meningkatkan keterampilan menulis teks eksposisi kelas x bertujuan untuk meningkatkan minat siswa terhadap mata pelajaran bahasa Indonesia khususnya keterampilan menulis. Pada saat pandemi covid-19 proses belajar mengajar tidak lagi dilakukan di kelas melainkan di rumah masing-masing dengan pembelajaran daring, sehingga pengajar dituntut untuk kreatif dalam menggunakan model dan media pembelajaran yang dapat membangun suasana belajar yang efektif agar tercapainya tujuan pembelajaran. Penerapan model pembelajaran flipped classroom berbantuan kahoot ini telah diterapkan pada kelas x SMA Triguna Utama bertujuan membangun minat belajar siswa pada keterampilan menulis teks eksposisi pada pembelajaran daring. Hasil dari penelitian adalah kefektifan pada saat pembelajaran daring dengan menerapkan model pembelajaran flipped classroom berbantuan kahoot dan juga nilai tes siswa yang mengalami peningkatan dan mencapai KKM yang ditentukan sekolah.
Analisis Penerapan Sistem Penunjang Keputusan Pemberi Kredit Mobil Pada PT. Astra Daihatsu Cabang Kramat Jati
Authors: Hendrian Senna , Himawan Imam 
Published: December 2021

Tujuan Penelitian adalah untuk menghasilkan sistem penunjang keputusan pemberi kredit mobil pada PT. Astra Daihatsu cabang Kramatjati. Membantu proses pengambilan keputusan penentuan pemberian kredit mobil pada PT. Astra Daihatsu cabang Kramatjati. Permasalahan yang dihadapi adalah proses pengambilan keputusan penentuan pemberian kredit mobil belum dilakukan secara sistematis. Metode penelitian yang dilakukan ini adalah dengan menggunakan metode Simple Additive Weighting (SAW). Metode SAW merupakan salah satu metode untuk membantu menyusun suatu prioritas dari berbagai pilihan dengan menggunakan beberapa kriteria. Karena sifatnya yang multi kriteria, SAW cukup banyak digunakan dalam penyusunan prioritas. SAW juga memberikan penilaian lebih tepat karena didasarkan pada nilai kriteria dari bobot preferensi yang sudah di tentukan. Selain itu, penulis juga melakukan penelitian dengan metode pengumpulan data dengan cara Observasi, Wawancara dan Dokumentasi. Pembuatan laporan-laporan. Analisis Sistem Penunjang Keputusan Pemberi Kredit Mobil pada PT. Astra Daihatsu Cabang Kramatjati telah berhasil dibangun dengan menggunakan aplikasi berbsais bahasa java Netbeans dan basis data MySQL. Sistem pendukung keputusan dengan menggunakan metode Simple Additive Weighting (SAW) ini dirancang untuk mempermudah proses seleksi kelayakan kredit mobil pada PT. Astra Daihatsu Cabang Kramatjati dimana semua proses dari mulai rekap data Admin, Mobil, dll, hingga proses penilaian dan penentuan bobot nilai dilakukan secara sistematis. Hasil pengujian fungsional menunjukan bahwa fungsi-fungsi yang terdapat pada aplikasi berjalan dengan baik dan sesuai dengan kebutuhan dan rancangan. Pembuatan laporan-laporan seluruh kegiatan dari mulai rekap data admin, hingga rekap hasil analisis dapat dengan mudah dilakukan, karena data yang diinput disimpan dalam basis data, yang mana dapat diolah setiap waktu. Kata Kunci: Sistem Penunjang Keputusan (SPK), Kredit mobil, Simple Additive Weighting (SAW), Daihatsu.
Hubungan konsep diri dengan interaksi sosial siswa SMPN 253 Jakarta
Authors: Noviyanti Adeliya , Miskanik Miskanik , Sunarto T 
Published: December 2021

siswa di sekolah diharapkan mampu menjalin interaksi sosial yang positif dan dinamis dengan seluruh warga sekolah. Kenyataanya masih terdapat siswa yang belum mampu berinteraksi sosial secara optimal. Konsep diri ditengarai berhubungan dengan keadaan ini. Penelitian ini bertujuan untuk mengetahui hubungan antara konsep diri dengan interaksi sosial siswa SMPN 253 Jakarta. Penelitian ini adalah penelitian kuantitatif dengan menggunakan metode korelasi. Data diperoleh melalui penyebaran kuesioner kepada siswa. Sampel dalam penelitian ini berjumlah 60 siswa dengan menggunakan teknik random sampling. Hasil penelitian mengungkapkan bahwa terdapat hubungan antara konsep diri dengan interaksi sosial siswa SMPN 253 Jakarta.
Clinical application of AIMS65 score to predict outcome in patients with acute upper gastrointestinal bleeding
Authors: Maharjan Kijan , Mandal Rajesh Kumar , Shrestha Sanjay 
Published: December 2021

BACKGROUND: Acute upper gastrointestinal bleeding (AUGIB) is a potentially life-threatening condition that requires rapid assessment in the emergency department. The current available scores are complex and have not been widely used in clinical practice. AIMS65 score is a simple score that can be used to risk stratify patients with AUGIB.
METHODS: This was a descriptive cross-sectional study done at a single tertiary centre, NAMS, Bir Hospital among the patients presenting with AUGIB from August 2018 to January 2019. AIMS65 scores were calculated in patients presenting with acute UGIB by allotting 1 point each for albumin level < 3g/dl, INR > 1.5, alteration in mental status, systolic blood pressure ≤90 mm Hg, and age ≥65 years. Risk stratification was done during the initial 12 hours of hospital admission.
RESULTS: A total of 84 patients consisting of 68 males and 16 females were enrolled in our study, with age ranging from 27 to 80 years. ICU admission, endoscopic therapy and blood transfusion were required in 22,44 and 49 patients respectively. In-patient mortality, the need for blood transfusion, endoscopic therapy or ICU admission were higher in those with AIMS65 score ≥ 2 showing statistically significant positive association (p=0.000).
CONCLUSION: AIMS65 score is a simple non-endoscopic risk score that can be applied in patients of acute upper gastrointestinal bleeding to risk stratify and to predict in-patient mortality, the need for blood transfusion, endoscopic therapy or ICU admission.
'A Kind of Sensory, Strange Thing to Experience': Speaking Environmental Disaster in the
Sea Empress Project
Archive
Authors: Cooper Timothy 
Published: December 2021

Abstract

This article explores embodied encounters with the
Sea Empress
oil spill of 1996 and their representation in oral narratives. Through a close reading of the personal testimonies collected in the
Sea Empress Project
archive, I examine the relationship between intense sensory experiences of environmental change and everyday interpretations of the disaster and its legacy. The article first outlines the ways in which this collection of voices reveals sensory memories, embodied affects and narrative choices to be deeply entwined in oral representations of the spill, disclosing a 'sensory event' that created a powerful awareness of both environmental surroundings and their relationship to everyday social processes. Then, reading these narratives against-the-grain, I argue that narrators' accounts tell a paradoxical story of a disaster that most now wish to forget, and reveal an ambivalent legacy of environmental change that is similarly consigned to the past. Finally, I relate this social forgetting of the
Sea Empress
to the wider history of environmental consciousness in modern Britain.
Faktor Pendukung Pendewasaaan Usia Perkawinan
Authors: Angraini Wulan , Amrullah Hilma , Febriawati Henni , Yanuarti Riska 
Published: December 2021

Introduction: Maturity of age marriage (PUP) plays as an important role in implementation of population development and family planning programs that aimed in improving quality of life. The proportion of adolescents in Province Bengkulu who know about family development is still below national figure, which is only 61,67%. Purpose: it is known factor maturity age marriage in Province Bengkulu. Methods: Design research cross-sectional used secondary data from Performance Survey and Accountability Program (SKAP) in 2019. Research time July to December 2020. The research population who were successfully interviewed was 69,662 families. The sample research was coverage in Province Bengkulu were 341 people. Data analysis are univariable and bivariable chi-square. Results: 71.6% of adolescents in Bengkulu Province plan to get married when they are 21 years old for women and 25 years for men. Gender is factor enabling that influences maturity of age marriage (p-value=0.013 OR: 1,89 CI 95%: 1,16-3,07). Residence of adolescents (p-value=0.374) and wealth index of adolescents (p value=0.491) did not have a significant relationship with maturity of age marriage of adolescent in Bengkulu Province. Conclusion: Understanding of the ideal age for marriage needs to be give early as possible to prevent child marriage. Interventions related to maturity age marriage in rural areas need to be increased for adolescents through PLB which is an extension of the BKKBN.