bluuebunny/crossref_metadata_2025_split huggingface dataset:
CONTENT AND QUALITY OF CHATGPT AS A SOURCE OF DEMENTIA INFORMATION: COMPARATIVE ANALYSES
Authors: Dosso Jill , Kailley Jaya , Angus Payton , Robillard Julie 
Published: January 2025

Abstract
There is significant demand for easily accessible, reliable online health information from older adults and their families (Soong et al., 2020). Online information about Alzheimer’s Disease and dementia ranges in quality from misleading and predatory to supportive and evidence-based (Robillard & Feng, 2016). ChatGPT was released to the public in November 2022 and is a well-known example of a new class of online tools, Large Language Models, which are generative artificial intelligence systems that can produce fluent, coherent answers to users’ questions based on extensive training data. In this work, we use a validated evaluation tool (Robillard et al., 2018) to evaluate the quality and content of information about dementia from ChatGPT-3.5 at two time points (2023, 2024) and from two versions of the model (free GPT-3.5, paid GPT-4). Prompts were developed using questions extracted from the FAQ pages of national dementia organization websites in Canada, USA, and Mexico. We found that all versions of ChatGPT were unbiased, remind the user to speak to a physician, and took an appropriately balanced tone. GPT-4, unlike GPT-3.5, links to specific, identifiable, dated sources for its claims including scientific research. All forms of ChatGPT had a high Flesch-Kincaid Grade Level, indicating moderate readability. Results indicate that ChatGPT, particularly GPT-4, can be a relatively high-quality source of dementia information for non-expert users. However, it is limited in its ability to link users to local resources. Findings can inform older adults, care partners, and healthcare professionals in their decision-making around use of this new tool.
NURSING HOME ADMISSION FROM RESIDENTIAL CARE FACILITY: NATIONAL HEALTH AGING TRENDS STUDY (NHATS) 2011–2019
Authors: Son Jung Yoen , Marriott Deanna J , Struble Laura , Weiyun Chen , Larson Janet 
Published: January 2025

Abstract
Limited studies have examined risk factors for nursing home admission among residents in residential care facilities (RCF), and prior research is limited by short follow-ups, which are insufficient to observe changes in health and nursing home admission. This study aimed to (1) identify baseline factors associated with transfers to a nursing home and (2) identify time-varying factors associated with transfer to a nursing home over 8 years, using a national dataset from the National Health Aging Trends Study (NHATS) collected between 2011 and 2019. We conducted Cox proportional hazards regression to examine candidate predictors (chronic conditions, hospitalization, sleep disturbances, mental health, physical performance, difficulties in activities of daily living (ADL), self-reported health, social and physical activity, and sociodemographic) associated with nursing home admission. Employing backward elimination, we built parsimonious final models for analysis. The analytic sample included 970 participants (mean age at baseline=85.7 years, 67.2% women, 83.1% White, mean length of stay at baseline=2.3 years) and 143 had transferred to nursing homes over 8 years. Those who had better physical performance at baseline (HR=0.83,CI=0.79-0.88) and were college educated (HR=0.58,CI=0.37-0.86) demonstrated a significantly lower risk for nursing home admission over 8 years. Residents who maintained physical activity (HR=0.56,CI=0.37-0.86), better physical performance (HR=0.87,CI=0.80-0.94), and fewer ADL difficulties (HR=1.13,CI=1.02-1.26) were at lower risk for nursing home admission over 8 years. Our findings can assist in identifying older adults in RCFs at risk of nursing home admission. Strategies to promote physical function and physical activity could be helpful to avoid/delay such admission.
THE COGNITIVE DECLINE TOWARD DEMENTIA AMONG NURSING HOME RESIDENTS
Authors: Hayajneh Audai 
Published: January 2025

Abstract
A scarcity of studies have examined the factors associated with mild cognitive impairment (MCI) as well as moderate cognitive impairment-as considered as dementia- among nursing home residents (NHRs). The aim of this study was to recognize the nature of relationship between the health risk variables, such as comorbidities, length of stay at hospital, the quality of life, the occurrence of depression, disability, and frailty, and dementia in NHRs. The study deployed cross-sectional design, using a convenient sample of 182 nursing home residents. The settings of the study were in the middle region of Jordan. Both stages of the MCI and dementia were determined through Montreal cognitive assessment (MoCA). Bivariate and multivariate analyses were utilized to explore the relationship between the health risk variables, and each of the MCI and dementia. There were significant differences between the stages of cognitive impairment (The MCI and dementia) in terms of age, the quality of life, comorbidities, depression, frailty. The variation in mental ability scores was dependent on the marital status of the participants, the monthly income, recently hospitalized, the level of depression, and frailty among older adults residing at nursing homes. The results of this study contribute significantly to building a healthcare management protocol to deal with nursing home residents with depressive symptoms as well as the deferral of the trajectory of development of dementia among those risky residents.
A MODIFIED MULTIFACTORIAL INTERVENTION FOR OLDER ADULTS WITH DIFFERENT KNEE OSTEOARTHRITIS SEVERITY
Authors: Aree-Ue Suparb , Roopsawang Inthira , Saraboon Natthayawadee 
Published: January 2025

Abstract
Knee osteoarthritis (OA) is a common health condition affecting older adults’ health worldwide. Several modalities to mitigate disease severity have been implemented; however, whether those interventions benefit all stages of disease severity has not been explored. This quasi-experimental study aimed to compare the effect of a modified multifactorial intervention program on health outcomes between older adults with mild and moderate knee OA severity. Ninety prospective participants who met the inclusion criteria were assigned into Group 1 (mild symptoms) or Group 2 (moderate symptoms). The modified multifactorial intervention program—health education about knee OA, weight control, quadriceps exercise, and home visits—was delivered to both groups lasting 12 weeks. The health outcomes (weight, psychological well-being, muscle strength, and knee OA severity) were assessed at baseline, 8-, and 12-week after enrollment using standard self-reported questionnaires and a 30-second sit-to-stand test. Data were analyzed using descriptive, independent-t-test, MANCOVA, and repeated measure MANOVA. Results revealed that the remaining 85 participants’ age ranged from 60 to 85 years, with a mean age of 68.8 years (SD = 8.6 years); almost were females (95.2%; n = 79). Although knee OA severity and psychological well-being significantly differed between the groups at baseline, there was no interaction effect on other dependent variables. Weight and muscle strength evaluated by a 30-second sit-to-stand test has no significant difference between groups. Results can be concluded that the modified multifactorial intervention program is beneficial to promote better knee joint function and health among older people with mild and moderate knee OA.
CHRONIC OBSTRUCTIVE PULMONARY DISEASE SELF-MANAGEMENT USING TECHNOLOGY IN DAILY LIFE: A PILOT STUDY
Authors: Woo Seoyoon , Ferrell Anastasiya , Chulak Jamy 
Published: January 2025

Abstract

Rationale
Self-management is crucial to preventing lung function decline and improving the quality of life but is rarely performed daily in people with chronic obstructive pulmonary disease (COPD). During the COVID-19, they were forced to use telemedicine and telerehabilitation for support. However, the extent to which such technology is used to manage COPD remains unknown. This study aimed to examine the use of technology for COPD self-management and its barriers and facilitators.

Methods
A cross-sectional study using an online survey method was conducted. People with COPD(N=102; mean age=44years) completed a set of questionnaires, including the Self-Management Assessment Scale and the Media and Technology Usage and Attitudes Scale, and open-ended questions. Descriptive statistics, multiple regressions, and the interpretative thematic approach were used to analyze the data.

Results
Compared to mobile device usage(94.2%), only 3.9% used it to self-manage COPD. However, over 60% expressed a willingness to use mobile apps for self-management. eHealth literacy significantly predicted both Media and Technology Usage(β=0.70,p=0.001) and Attitudes(β=0.20,p&lt; 0.001). COPD self-efficacy significantly predicted all five domains of self-management needs: knowledge(β=0.33,p=0.003), goals for future(β=0.36,p=0.02), daily routines(β=03,p=0.004), emotional adjustment(β=0.53,p&lt; 0.001), and social support(β=0.51,p=0.02). Barriers to using mobile apps included their reliability, forgetfulness, and usability, just to name a few. Mobile apps for COPD self-management can be more attractive if they feature monitoring and recording of symptoms and provide relevant resources.

Conclusion
This study identified factors influencing the use of technology for COPD self-management. The findings can be considered in designing self-management intervention tools to help better manage COPD.
OLDER AGE AND DEPRESSION AS THE RISK FACTORS FOR HYPERTENSION AMONG NORTH KOREAN DEFECTORS
Authors: Chu Sang Hui , Kim Oksim , Kim Hokon 
Published: January 2025

Abstract
Observations indicate a low obesity prevalence among North Korean Defectors (NKRs), who fled to South Korea, attributed to undernourishment prior to their arrival. With an aging NKR demographic, there’s growing concern over chronic disease management, including hypertension. Previous studies reported a high or comparable prevalence of elevated blood pressure among NKRs, yet the influence of mental health on hypertension has been underexplored. Given the high rates of trauma-related conditions and depression within this group, these factors could significantly elevate hypertension risk. Understanding hypertension risk factors across different age groups could inform tailored management strategies for older NKRs. This study assessed the impact of mental health on hypertension among 449 NKRs categorized into three age groups: younger (&lt; 30 years; n=141), middle-aged (40-59 years; n=243), and older (≥ 60 years; n=65). The assessment of Post-Traumatic Stress Disorder (PTSD)/complex PTSD (CPTSD) employed the International Trauma Questionnaire (ITQ), covering six domains: re-experiencing, avoidance, sense of threat, affective dysregulation, negative self-concept, and disturbance in relationships. Hypertension and depression were identified through self-reported diagnoses. Logistic regression analysis revealed that, in addition to older age, depression was significantly associated with hypertension, but not PTSD/CPTSD, after controlling for gender, living alone, and residency period in South Korea. These findings suggest the necessity of prioritizing mental health improvement, especially depression, in hypertension management among NKRs. This work was supported by the Basic Science Research Program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education (2019R1I1A2A01058746).
OUTCOMES OF AN INTEGRATED HEALTH CARE AND COMMUNITY PROVIDER INTERPROFESSIONAL TEAM
Authors: Drost Jennifer , Hughes Michelle , Fosnight Sue , Marchiano Joseph , Hazelett Susan , Gareri Michele , Chrzanowski Brandi 
Published: January 2025

Abstract
Traditional medical care accounts for 10% of health outcomes, while social determinants of health account for over 60%. To address complex interactions between medical illness, social and behavioral health issues, and medications, effective care requires collaboration between medical and community-based providers. We have developed a collaborative interprofessional model of care between a health system and the local Area Agency on Aging (AAoA) called the Care Management Interdisciplinary Team (CMIT). CMIT care managers (social workers and nurses) complete evaluations of consumers focused on concerns around recent health care utilization (ED visits/hospitalizations), falls, medications, home safety, and behavioral health concerns. Care managers (CM) then present these complex older adults to the team, including geriatric medicine and pharmacy specialists, which develops care plans that are implemented by the CM and the consumer’s primary care physician. CM presented cases between January-December 2023 and worked to follow up at 3 months. Eighty-one consumers were presented to the CMIT team over a 1-year period. A 3-month follow up is available for 44 consumers (54%). Of those with 3-month follow ups, at baseline, 10 (23%) consumers had recent health care utilization episodes, 17 (39%) had concerns about falls, 17 (39%) had concerns about medications, 21 (48%) had home safety concerns, and 10 (23%) had behavioral health concerns. At the 3-month follow up, 5 consumers had improved health care utilization, 6 fewer had falls, 5 had medication changes, 13 had improved home safety concerns, and 7 had improved behavioral health concerns.
REDUCING OR STOPPING MEDICATIONS FOR CHRONIC PAIN: VIEWS AMONG COMMUNITY-DWELLING OLDER ADULTS
Authors: Noh Hyunjin , Jeong Haelim , Kan Denise , Lee Lewis 
Published: January 2025

Abstract
Effective pain control is vital in enhancing quality of life. As the dangers of adverse drug interactions are recognized, there is a shift towards reducing reliance on medications that could be ineffective or harmful (known as deprescribing) and a push for embracing non-drug methods in managing pain. However, limited research exists on how older adults perceive deprescribing. Therefore, this study aimed to understand the views of deprescribing among community-dwelling older adults living with multiple health conditions and chronic pain. Participants were recruited from the Alabama Area Agency on Aging offices. Eligible participants were 65+, Alabama residents living outside of nursing homes, cognitively intact, have more than one chronic illness and chronic pain, and take medications for the illnesses, including pain medicine. Individual, open-ended interviews were conducted by phone, asking about their experiences with taking multiple medications and thoughts about deprescribing. Thematic analysis of interviews with 30 participants revealed facilitators, barriers, and needs for deprescribing. Facilitators for deprescribing included interest in more holistic methods for pain management, concerns for long-term side effects, and desire for better quality of life, while barriers included fear of worsening pain, reluctance to change in medical regimen, and lack of support from healthcare providers. Needs for deprescribing included credible information from their healthcare providers about deprescribing and social support in deprescribing decision-making. These findings suggest that older adults may benefit from education and advocacy efforts designed to improve their knowledge and self-efficacy and healthcare providers’ willingness to openly communicate with older adults about deprescribing.
EFFECTIVENESS OF TARGETED WEB-BASED ADVERTISING WHEN RECRUITING OLDER ADULTS FOR A CLINICAL TRIAL
Authors: Baldyga Kathryn , Millar Courtney , Iloputaife Ike , Taffet George , Lipsitz Lewis 
Published: January 2025

Abstract
Recruiting older adults for clinical trials can be particularly challenging. Our objective was to determine if targeted web-based advertising is an effective recruitment strategy. The STAMINA Study (Senolytics To Alleviate Mobility Issues and Neurological Impairments in Aging) is a pilot 12-week study of the effects of intermittent Quercetin and Dasatinib on cognition and mobility in older adults with mild cognitive impairment and slow gait. Individuals were initially recruited using traditional strategies such as presentations and advertisements in clinical practices, subject registries, and community sites. After 10 months of slow recruitment rates, a web-based advertising company was used to deliver targeted online study advertisements based on an individual’s browsing history. Recruitment rates were calculated based on the total number of individuals engaged in each stage of the recruitment process, divided by the number of months the strategy was utilized. Web-based advertising reached more individuals (~40 individuals/month) compared to traditional methods (~5 individuals/month). Compared to traditional methods, web-based methods had at least twice the rate of expressed interest, telephone and in-person screening completion, eligibility, and enrollment. All individuals recruited from traditional methods completed the intervention, while 3 individuals recruited from web-based advertising dropped out. Those recruited using web-based advertisements tended to be younger compared to traditional methods, but were similar in racial distribution and education. Targeted web-based advertisements may be more effective in recruiting older adults for clinical trials than traditional recruitment methods, but need further evaluation of compatible study designs, potential population bias, and cost effectiveness.
IMPACT OF ART-BASED INTERVENTION ON BRAIN FUNCTIONAL CONNECTIVITY IN OLDER ADULTS ALONG THE ALZHEIMER’S CONTINUUM
Authors: Huang Chenshan , Yan Yuanjiao , Shi Yanhong , Lin Rong , Li Hong 
Published: January 2025

Abstract

Background
Combined art-based interventions (CAIs) are considered effective treatment options for older adults along the Alzheimer’s disease (AD) continuum; however, the neural mechanisms underlying associated changes in neurocognitive performance remain unclear. Thus, we aimed to investigate the impact of a CAI programme in older adults along the AD continuum and to understand its mechanism.

Methods
This parallel-arm randomised controlled trial was conducted between April 2021 and January 2023. Participants were randomised in a 1:1 ratio to either intervention group (IG) or waitlist control group (WG). The IG underwent a 16-week CAI programme. Neuropsychological assessments and magnetic resonance imaging were conducted before and after the intervention.

Results
After the intervention, the IG showed greater improvement in general cognitive function, language, and memory than the WG. Significant differences were observed in the functional connectivity (FC) values in the temporal and cerebellar anterior lobes, fusiform, inferior occipital, and lingual gyri, and perirhinal and visual cortices between the groups. Further analyses showed that FC values reduced in these regions in the IG. In addition, changes in FC values were positively correlated with those in neuropsychological test scores in the IG.

Conclusions
Our study suggests that the CAI programme can effectively improve general cognitive function, language, and memory in older adults along the AD continuum. These improvements may be changed due to decreases in FC in key brain regions, deepening the understanding of the neurocentral mechanisms that act as a tool for improving cognitive function.
TESTING THE IMPLEMENTATION FRAMEWORK FOR BEHAVIORAL AND LIFESTYLE INTERVENTIONS IN ALZHEIMER’S DISEASE (MOBILIZE)
Authors: Salisbury Dereck , Lin Vankee , Yu Fang 
Published: January 2025

Abstract

Introduction
Implementing multi-site behavioral intervention trials in Alzheimer’s disease (AD) has many unique challenges, leading to substantial variations in delivered intervention doses and cognitive findings. These issues can be addressed by the IMplementation Framework fOr Behavioral and LIfestyLe Interventions In AlZheimer’s DiseasE (MOBILIZE) that was developed to guide the design and implementation of behavioral interventions in AD.

Methods
This study systematically evaluated the implementation outcomes of the multi-site aerobic exercise and cognitive training (ACT) trial that employed MOBILIZE. Building on the person-centered care principle, MOBILIZE includes three implementation outcomes (screening, intervention adherence, and safety) with corresponding team processes to guide trial implementation. Screening was operationalized as the duration (days) between each screening visit, last screening visit to enrollment, and enrollment to first intervention session. Intervention adherence outcomes included: adherence (attendance), session dose adherence (calculated by dividing the number of sessions that achieved &gt;=70% of the prescribed session dose / total number of sessions completed), and days required to complete the prescribed 72 sessions. Safety was operationalized as the type, number, and severity of study-related adverse events (AEs). RESULTS. The sample (n=146) was 73.8±5.7 years in age and 23.4±2.1 on Montreal Cognitive Assessment score, with 48.0% female, and 91.8% white. Screening-to-enrollment averaged 117.4±71.7 days. Intervention adherence was 77.4%±28.3%. There was 9-study related adverse events. Screening-to-enrollment and intervention adherence differed across sites, mainly due to COVID-19 influence. CONCLUSIONS. MOBILIZE helped the ACT Trial achieve high intervention adherence and safety and may be particularly important for early-stage and multi-site trials in AD.
ANALYZING THE INFLUENCE OF MIDLIFE EMPLOYMENT TRAJECTORIES ON COGNITIVE AGING IN CHILE
Authors: Delaporte Magdalena , Behrman Jere 
Published: January 2025

Abstract
As the global population ages, understanding the factors contributing to healthy aging becomes increasingly crucial. This paper delves into the relationship between mid-life employment trajectories and later-life cognition, utilizing a Chilean longitudinal dataset. Employing the Group-Based Trajectory Model (GBTM), distinct employment trajectories for males and females between 1980 and 2016 are estimated. Subsequently, we link these trajectories to cognitive function scores to investigate the associations between individual trajectories and cognitive function in later life. Preliminary findings reveal significant associations between certain cognitive domains and labor force participation trajectories. We find four distinct labor force participation trajectories for men and women. Results show that men that have a high probability of continued employment demonstrate better cognitive outcomes, including orientation, memory, attention, and executive function. For women, a higher likelihood of working during between ages 30 to 60 correlates with improved performance in delayed memory, attention, and executive function. These results provide valuable insights for policymakers and practitioners seeking to enhance cognitive well-being among older adults.