bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accusing and Identifying theKalku: The Perception of Sorcery in Mapuche Society (Seventeenth to Eighteenth Centuries)
Authors: Ambrogio Oriol 
Published: July 2021

AbstractThis article examines accusations of sorcery as a way to understand the perceptions of sorcery among the Mapuche of central-southern Chile during the colonial period. Local communities believed that illnesses and unfortunate events were caused by the actions of sorcerers, known as kalku, and therefore consulted ritual healers and diviners, the machi and dugul, to identify and punish the supposed evildoers. In accusing local members of being kalku, the ritual specialists expressed a precise perception of sorcery and developed clear strategies for counteracting the sorcerers. This article argues that the accusations of sorcery became political and social instruments in the hands of the local authorities and that they shaped the meaning of sorcery and its perception among the Mapuche.
Estimating Adult Death Rates From Sibling Histories: A Network Approach
Authors: Feehan Dennis M. , Borges Gabriel M. 
Published: July 2021

AbstractHundreds of millions of people live in countries that do not have complete death registration systems, meaning that most deaths are not recorded and that critical quantities, such as life expectancy, cannot be directly measured. The sibling survival method is a leading approach to estimating adult mortality in the absence of death registration. The idea is to ask survey respondents to enumerate their siblings and to report about their survival status. In many countries and periods, sibling survival data are the only nationally representative source of information about adult mortality. Although a vast amount of sibling survival data has been collected, important methodological questions about the method remain unresolved. To help make progress on this issue, we propose reframing the sibling survival method as a network sampling problem. This approach enables a formal derivation of statistical estimators for sibling survival data. Our derivation clarifies the precise conditions that sibling history estimates rely on, leads to internal consistency checks that can help assess data and reporting quality, and reveals important quantities that could potentially be measured to relax assumptions in the future. We introduce the R package siblingsurvival, which implements the methods we describe.
Occupational Inflexibility and Women's Employment During the Transition to Parenthood
Authors: Ishizuka Patrick , Musick Kelly 
Published: July 2021

AbstractThe typical U.S. workplace has adapted little to changes in the family and remains bound to norms of a workweek of 40 or more hours. How jobs are structured and remunerated within occupations shapes gender inequality in the labor market, and this may be particularly true at the critical juncture of parenthood. This study provides novel evidence showing how the inflexibility of occupational work hours shapes new mothers' employment. We use a fixed-effects approach and individual-level data from nationally representative panels of the Survey of Income and Program Participation (N = 2,239 women) merged with occupational characteristics from the American Community Survey. We find that women in pre-birth occupations with higher shares working 40 or more hours per week and higher wage premiums to longer work hours are significantly less likely to be employed post-birth. These associations are small in magnitude and not statistically significant for men, and placebo regressions with childless women show no associations between occupational inflexibility and subsequent employment. Results illustrate how individual employment decisions are jointly constrained by the structure of the labor market and persistent gendered cultural norms about breadwinning and caregiving.
Žižek
Authors: Gane Mike 
Published: July 2021

Abstract
Two very substantial new books by Slavoj Žižek were published in early 2020; they are at two different ends of the spectrum that runs from obscure Hegelian-Lacanian philosophical reflections (Sex and the Failed Absolute) to uninhibited short Maoist-Leninist political “interventions” (A Left That Dares to Speak Its Name). Žižek claims to have completed an intellectual system (continuing the idea of earlier essays) that, as a philosophical foundation, currently informs his political writings. The review follows the sexual problematic through Žižek's philosophy (its antihumanist ethical and political orientations) to the politics of “the impossible” act or event.
Suv420 enrichment at the centromere limits Aurora B localization and function
Authors: Herlihy Conor P. , Hahn Sabine , Hermance Nicole M. , Crowley Elizabeth A. , Manning Amity L. 
Published: July 2021

ABSTRACT
Centromere structure and function are defined by the epigenetic modification of histones at centromeric and pericentromeric chromatin. The constitutive heterochromatin found at pericentromeric regions is highly enriched for H3K9me3 and H4K20me3. Although mis-expression of the methyltransferase enzymes that regulate these marks, Suv39 and Suv420, is common in disease, the consequences of such changes are not well understood. Our data show that increased centromere localization of Suv39 and Suv420 suppresses centromere transcription and compromises localization of the mitotic kinase Aurora B, decreasing microtubule dynamics and compromising chromosome alignment and segregation. We find that inhibition of Suv420 methyltransferase activity partially restores Aurora B localization to centromeres and that restoration of the Aurora B-containing chromosomal passenger complex to the centromere is sufficient to suppress mitotic errors that result when Suv420 and H4K20me3 is enriched at centromeres. Consistent with a role for Suv39 and Suv420 in negatively regulating Aurora B, high expression of these enzymes corresponds with increased sensitivity to Aurora kinase inhibition in human cancer cells, suggesting that increased H3K9 and H4K20 methylation may be an underappreciated source of chromosome mis-segregation in cancer.
This article has an associated First Person interview with the first author of the paper.
The Bardet–Biedl syndrome complex component BBS1 controls T cell polarity during immune synapse assembly
Authors: Cassioli Chiara , Onnis Anna , Finetti Francesca , Capitani Nagaja , Brunetti Jlenia , Compeer Ewoud B. , Niederlova Veronika , Stepanek Ondrej , Dustin Michael L. , Baldari Cosima T. 
Published: July 2021

ABSTRACT
Components of the intraflagellar transport (IFT) system that regulates the assembly of the primary cilium are co-opted by the non-ciliated T cell to orchestrate polarized endosome recycling and to sustain signaling during immune synapse formation. Here, we investigated the potential role of Bardet–Biedl syndrome 1 protein (BBS1), an essential core component of the BBS complex that cooperates with the IFT system in ciliary protein trafficking, in the assembly of the T cell synapse. We demonstrated that BBS1 allows for centrosome polarization towards the immune synapse. This function is achieved through the clearance of centrosomal F-actin and its positive regulator WASH1 (also known as WASHC1), a process that we demonstrated to be dependent on the proteasome. We show that BBS1 regulates this process by coupling the 19S proteasome regulatory subunit to the microtubule motor dynein for its transport to the centrosome. Our data identify the ciliopathy-related protein BBS1 as a new player in T cell synapse assembly that functions upstream of the IFT system to set the stage for polarized vesicular trafficking and sustained signaling.
This article has an associated First Person interview with the first author of the paper.
Forecasting Airport Transfer Passenger Flow Using Real-Time Data and Machine Learning
Authors: Guo Xiaojia , Grushka-Cockayne Yael , De Reyck Bert 
Published: July 2021

Problem definition: Airports and airlines have been challenged to improve decision making by producing accurate forecasts in real time. We develop a two-phased predictive system that produces forecasts of transfer passenger flows at an airport. In the first phase, the system predicts the distribution of individual transfer passengers’ connection times. In the second phase, the system samples from the distribution of individual connection times and produces distributional forecasts for the number of passengers arriving at the immigration and security areas. Academic/practical relevance: To our knowledge, this work is the first to apply machine learning for predicting real-time distributional forecasts of journeys in an airport using passenger level data. Better forecasts of these journeys can help optimize passenger experience and improve airport resource deployment. Methodology: The predictive system developed is based on a regression tree combined with copula-based simulations. We generalize the tree method to predict distributions, moving beyond point forecasts. We also formulate a newsvendor-based resourcing problem to evaluate decisions made by applying the new predictive system. Results: We show that, when compared with benchmarks, our two-phased approach is more accurate in predicting both connection times and passenger flows. Our approach also has the potential to reduce resourcing costs at the immigration and transfer security areas. Managerial implications: Our predictive system can produce accurate forecasts frequently and in real time. With these forecasts, an airport’s operating team can make data-driven decisions, identify late passengers, and assist them to make their connections. The airport can also update its resourcing plans based on the prediction of passenger flows. Our predictive system can be generalized to other operations management domains, such as hospitals or theme parks, in which customer flows need to be accurately predicted.Funding: This work was funded by Eurocontrol (APOC Business Process Reengineering Big Data Study) [Grant 15-220643-AWP6.3.1].Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2021.0975 .
In-hours acute home visits by advanced nurse practitioners in primary care: a qualitative study
Authors: Wells Alison , Tolhurst Edward 
Published: July 2021

Background: The extension of roles within the primary care team is one approach recommended to address the shortage of GPs in the UK. A key aspect of care that advanced nurse practitioners (ANPs) can undertake is acute home visits. Aim: To evaluate the perspectives of ANPs performing acute in-hours home visits in primary care. Methods: Qualitative data were gathered in eight semi-structured interviews across a primary care locality, then analysed via a process of thematic analysis. Findings: Three key themes were identified: providing holistic care; engaging with the home setting; and negotiating role ambiguity. Conclusion: Practices wishing to involve ANPs in acute home visits should ensure clear definition and good understanding of the ANP role. Effective interprofessional relationships should be fostered with appropriate mentorship and clinical supervision to support ANPs in optimising their contribution to acute home visits.
Can PROMIS measures be used to create subgroups for patients seeking orthopaedic care?
Authors: George Steven Z. , Yan Xiaofang , Luo Sheng , Olson Steven A. , Reinke Emily K. , Bolognesi Michael P. , Horn Maggie E. 
Published: July 2021

Aims Patient-reported outcome measures have become an important part of routine care. The aim of this study was to determine if Patient-Reported Outcomes Measurement Information System (PROMIS) measures can be used to create patient subgroups for individuals seeking orthopaedic care. Methods This was a cross-sectional study of patients from Duke University Department of Orthopaedic Surgery clinics (14 ambulatory and four hospital-based). There were two separate cohorts recruited by convenience sampling (i.e. patients were included in the analysis only if they completed PROMIS measures during a new patient visit). Cohort #1 (n = 12,141; December 2017 to December 2018,) included PROMIS short forms for eight domains (Physical Function, Pain Interference, Pain Intensity, Depression, Anxiety, Sleep Quality, Participation in Social Roles, and Fatigue) and Cohort #2 (n = 4,638; January 2019 to August 2019) included PROMIS Computer Adaptive Testing instruments for four domains (Physical Function, Pain Interference, Depression, and Sleep Quality). Cluster analysis (K-means method) empirically derived subgroups and subgroup differences in clinical and sociodemographic factors were identified with one-way analysis of variance. Results Cluster analysis yielded four subgroups with similar clinical characteristics in Cohort #1 and #2. The subgroups were: 1) Normal Function: within normal limits in Physical Function, Pain Interference, Depression, and Sleep Quality; 2) Mild Impairment: mild deficits in Physical Function, Pain Interference, and Sleep Quality but with Depression within normal limits; 3) Impaired Function, Not Distressed: moderate deficits in Physical Function and Pain Interference, but within normal limits for Depression and Sleep Quality; and 4) Impaired Function, Distressed: moderate (Physical Function, Pain Interference, and Sleep Quality) and mild (Depression) deficits. Conclusion These findings suggest orthopaedic patient subgroups differing in physical function, pain, and psychosocial distress can be created from as few as four different PROMIS measures. Longitudinal research is necessary to determine whether these subgroups have prognostic validity. Cite this article: Bone Jt Open 2021;2(7):493–502.
Observation of rotational coherence in an excited state of CO+
Authors: Wan Y. X. , Fu B. T. , Xie H. Q. , Yu S. P. , Lei H. B. , Zhang F. B. , Zhang Z. H. , Qiao L. L. , Li G. H. , Zhao J. , Zhao Z. X. , Yao J. P. , Cheng Y. 
Published: July 2021

The vacuum ultraviolet (VUV) radiation is generated in the strong-field-ionized CO molecules through

2

+

1

resonance excitation with two-color femtosecond laser pulses. When scanning the relative delay between two pump pulses, the rotational-resolved VUV radiations show periodic oscillations lasting as long as 500 ps. Fourier analysis reveals that these oscillations correspond to rotational beat frequencies of the

A

2

Π

i

state of

C
O

+

, which is the result of multi-channel interference during the resonant excitation process. High resolution of Fourier transform spectra up to

0.067

c
m

−
1

allows us to obtain the fine energy levels of the

A

2

Π

i

state. The theoretical calculation is in good agreement with the experimental observation. This work reveals the rotational coherence of the ionic excited state and shows the prospect of rotational coherence spectroscopy in measuring fine structures of molecular ions.
Generation and transmission of phase-stable coherent multi-band linear frequency modulated signals
Authors: Li Baiyu , Wang Xi , Wei Wei , Xie Weilin , Dong Yi 
Published: July 2021

We present a coherent multi-band linear frequency modulated (LFM) signal generation and transmission system based on dual optical frequency combs (OFCs). In the proposed scheme, the two OFCs are phase-locked to ensure high coherence of the generated multi-band LFM signals. A round-trip phase correction is adopted to stabilize the time delay of the fiber transmission and enable the system to resist temperature variation. In the demonstration experiment, the generated multi-band LFM signals across L, S, and C frequency bands has a bandwidth of 200 MHz in each band. The root-mean-square (RMS) phase deviation of the multi-band signal is below

4
×

10

−
3

r
a
d

after 1.2 km fiber transmission. During 1°C temperature variation, the RMS phase drift is suppressed from 1 rad to 0.1 rad. The high signal coherence between different bands and the capability of resisting temperature variation are highly desired for a multi-band distributed radar system.
Comparative advantages of a type-II superlattice barrier over an AlGaSb barrier for enhanced performance of InAs/GaSb LWIR nBn photodetectors
Authors: Lee Hyun-Jin , Jang Ahreum , Kim Young Ho , Jung Han , Bidenko Pavlo , Kim Sanghyeon , Kim Minje , Nah Junghyo 
Published: July 2021

The barrier layer in InAs/GaSb LWIR nBn detector is usually composed of AlGaSb alloy, which has a non-negligible valence band offset and is sensitive to chemical solutions. In this work, we investigated a type-II superlattice (T2SL) barrier that is homogeneous with the T2SL absorber layer in order to resolve these drawbacks of the AlGaSb barrier. The lattice mismatch of the T2SL barrier was smaller than that of the AlGaSb barrier. At

−

70

m
V

and 80 K, the dark current density and the noise equivalent temperature difference of the nBn devices with the T2SL barrier were

4.4

×

1

0

−
6

A

/

c
m

2

and 33 mK, respectively.
Clinical manifestations and health outcomes associated with Zika virus infections in adults: A systematic review
Authors: Halani Sheliza , Tombindo Panashe E. , O’Reilly Ryan , Miranda Rafael N. , Erdman Laura K. , Whitehead Clare , Bielecki Joanna M. , Ramsay Lauren , Ximenes Raphael , Boyle Justin , Krueger Carsten , Willmott Shannon , Morris Shaun K. , Murphy Kellie E. , Sander Beate 
Published: July 2021

Background
Zika virus (ZIKV) has generated global interest in the last five years mostly due to its resurgence in the Americas between 2015 and 2016. It was previously thought to be a self-limiting infection causing febrile illness in less than one quarter of those infected. However, a rise in birth defects amongst children born to infected pregnant women, as well as increases in neurological manifestations in adults has been demonstrated. We systemically reviewed the literature to understand clinical manifestations and health outcomes in adults globally.

Methods
This review was registered prospectively with PROPSERO (CRD 42018096558). We systematically searched for studies in six databases from inception to the end of September 2020. There were no language restrictions. Critical appraisal was completed using the Joanna Briggs Institute Critical Appraisal Tools.

Findings
We identified 73 studies globally that reported clinical outcomes in ZIKV-infected adults, of which 55 studies were from the Americas. For further analysis, we considered studies that met 70% of critical appraisal criteria and described subjects with confirmed ZIKV. The most common symptoms included: exanthema (5,456/6,129; 89%), arthralgia (3,809/6,093; 63%), fever (3,787/6,124; 62%), conjunctivitis (2,738/3,283; 45%), myalgia (2,498/5,192; 48%), headache (2,165/4,722; 46%), and diarrhea (337/2,622; 13%). 36/14,335 (0.3%) of infected cases developed neurologic sequelae, of which 75% were Guillain-Barré Syndrome (GBS). Several subjects reported recovery from peak of neurological complications, though some endured chronic disability. Mortality was rare (0.1%) and hospitalization (11%) was often associated with co-morbidities or GBS.

Conclusions
The ZIKV literature in adults was predominantly from the Americas. The most common systemic symptoms were exanthema, fever, arthralgia, and conjunctivitis; GBS was the most prevalent neurological complication. Future ZIKV studies are warranted with standardization of testing and case definitions, consistent co-infection testing, reporting of laboratory abnormalities, separation of adult and pediatric outcomes, and assessing for causation between ZIKV and neurological sequelae.
Identification and engraftment of new bacterial strains by shotgun metagenomic sequence analysis in patients with recurrent Clostridioides difficile infection before and after fecal microbiota transplantation and in healthy human subjects
Authors: Verma Sandeep , Dutta Sudhir K. , Firnberg Elad , Phillips Laila , Vinayek Rakesh , Nair Padmanabhan P. 
Published: July 2021

Background
Recurrent Clostridioides diffícile infection (RCDI) is associated with major bacterial dysbiosis and colitis. Fecal microbiota transplantation (FMT) is a highly effective therapeutic modality for RCDI. While several studies have identified bacterial species associated with resolution of symptoms in patients, characterization of the fecal microbiome at the bacterial strain level in RCDI patients before and after FMT and healthy donors, has been lacking. The aim of this study was to examine the ability of bacterial strains from healthy donors to engraft in the gastrointestinal tract of patients with RCDI following FMT.

Methods
Fecal samples were collected from 22 patients with RCDI before and after FMT and their corresponding healthy donors. Total DNA was extracted from each sample and analyzed by shotgun metagenomic sequencing. The Cosmos-ID analysis platform was used for taxonomic assignment of sequences and calculation of the relative abundance (RA) of bacterial species and strains. From these data, the total number of bacterial strains (BSI), Shannon diversity index, dysbiosis index (DI), and bacterial engraftment factor, were calculated for each strain.

Findings
A marked reduction (p<0·0001) in the RA of total and specific bacterial strains, especially from phylum Firmicutes, was observed in RCDI patients prior to FMT. This change was associated with an increase in the DI (p<0·0001) and in pathobiont bacterial strains from phylum Proteobacteria, such as Escherichia coli O157:H7 and Klebsiella pneumoniae UCI 34. BSI was significantly lower in this group of patients as compared to healthy donors and correlated with the Shannon Index. (p<0·0001). Identification and engraftment of bacterial strains from healthy donors revealed a greater diversity and higher relative abundance of short-chain fatty acid (SCFA)-producing bacterial strains, including Lachnospiraceae bacterium 5_1_63FAA_u_t, Dorea formicigenerans ATCC 27755, Anaerostipes hadrusand others, in RCDI patients after FMT.

Interpretation
These observations identify a group of SCFA-producing bacterial strains from healthy donors that engraft well in patients with RCDI following FMT and are associated with complete resolution of clinical symptoms and bacterial dysbiosis.