bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recycling paper industry: Analysis of raw material consumption in Indonesia
Authors: Romas M S , Martini S 
Published: May 2021

Abstract
The recycling paper industry has a good potential market. The industry used recycled paper such as Old Corrugated Containers (OCC), Old Newspaper (ONP), mixed waste paper, and Sorted White Ledger (SWL) as raw material. In Indonesia, commonly, the industry got the raw material of about 50% by importing. The government provides regulation to ensure the sustainability of the industrial activity, that is the process of importing recycled paper and internal regulation to increase local raw materials. The objectives of the research were to study the chosen raw material for the recycling paper industry and to analyze the positioning strategy of consumption raw material for the recycling paper industry in Indonesia. This research used a qualitative description method by the Analytical Hierarchy Process (AHP) and Strength Weakness Opportunities Threat (SWOT) analysis. The data were obtained from a questionnaire distributed to the paper industry, paper researcher, and relevant agencies. Based on AHP, the strength criteria to choose raw material is the regulation and availability of raw material with values 0.323 and 0.243; and the alternative chosen is recycled paper raw material import. The result of SWOT analysis, the recycling paper industry in Indonesia, has an Internal Factor Analysis Strategy (IFAS) 0.05, and an External Factor Analysis Strategy (EFAS) - 0.03. That showed from SWOT quadrant matrix, the position coordinate point of IFAS and EFAS in quadrant II. That means the positioning strategy is diversification. The government, recycling paper industry, and relevant agencies to corporate to increase the collecting rate of recycled paper.
Agglomeration of Pt nanoparticles on the g-C3N4 surface dominated by oriented attachment mechanism and way of inhibition
Authors: Yan Fengpo , Zhang Hao , Zhang Yu , Yang Fugui 
Published: May 2021

Abstract
0.3 mol% platinum loaded g-C3N4 sample was prepared by photoreduction method to study the long-term stability of photocatalysts. For the first time, we have discovered the oriented attachment (OA) mechanism growth of Pt nanoparticles on g-C3N4 solid surface, which is completely different from Ostwald ripening (OR) or particle migration and coalescence (PMC) that previously reported. The Pt nanoparticles perform Brownian motion on the surface of g-C3N4 support under the collision of liquid molecules, then two or more nanoparticles attach together via the crystallographic orientation to construct larger ones. Al2O3 film prepared by atomic layer depositon was introduced to inhibit the Brownian motion of Pt nanoparticles. It is found that as the increase of the Al2O3 growth cycles, the photocatalytic hydrogen production of Pt/g-C3N4 coated by Al2O3 increase from 1.14 mmolg−1h−1 to 2.08 mmolg−1h−1 and then decrease to 1.4 mmolg−1h−1, and the apparent quantum efficiency (QE) also increase from 1.2% to 2.1% and then decrease to 1.4%. Meanwhile, the long-term stability of photocatalyst always increases. This work has revealed new pathway of photocatalytic nanoparticle growth on solid surface and proposed the method to prevent it.
A brief overview about the use of different bioactive liposome-based drug delivery systems in Peritoneal Dialysis and some other diseases
Authors: Singh Sandeep Kumar , Kumar Umesh , Guleria Anupam , Kumar Dinesh 
Published: May 2021

Abstract
Peritoneal dialysis (PD) is a promising way of treatment used for patients suffering from End-Stage Renal Failure (ESRF). Liposomes are nanocarriers comprised of lipid bilayers encapsulating an aqueous core. Liposomes are extensively used as drug delivery systems and several liposomal nanomedicines have been approved for clinical applications. Nanomedicine constitutes a new direction in peritonitis prevention using peritoneal dialysis (PD). In case of PD; there is a more risk of bacterial infection in the peritoneal cavity along with subcutaneous tunnel and catheter existing site. These infections are the most common complications associated with prolonged peritoneal dialysis (PD) therapy. To prevent such complications, patients used to treat with suitable antibiotic. Nanocarriers consist of assembly of nano-sized vehicles planned to deliver encapsulated/loaded bioactive(s) to the specific target (tissues or organs) and have provided prominent improved therapeutic efficacy for PD patients. The advantage of bioactive loaded nanocarrier has the efficient capacity to deliver at target specific site in PD. This review focuses mainly on the current use of different liposomal encapsulated bioactive compounds in drug delivery systems in the case of PD and other human diseases and briefly highlights the importance and use of different liposomal encapsulated antimicrobial agents to improve the PD technique.
Economic feasibility of wood-based structures—Improving urban carbon neutrality strategies
Authors: Talvitie Ilmari , Vimpari Jussi , Junnila Seppo 
Published: May 2021

Abstract
Countries and cities alike have set carbon neutrality goals for the near future. Urban areas are experiencing an increased demand for new housing developments, and buildings are responsible for one third of all greenhouse gas emissions. The relative share of construction emissions is increasing as energy production is de-carbonizing. Wooden structures have showcased potential in substantially decreasing these emissions. However, for the construction industry to utilize environmentally friendly products, the cost efficiency needs to be determined. Prior research does not present conclusive results regarding the construction costs or value of wooden buildings. This study aims to determine the economic feasibility of wood-based structures in housing.
We approach this by estimating the effect of wood on Finnish dwelling prices through hedonic regression analyses. Dwelling prices are analysed with transaction data from the Helsinki metropolitan area. It is provided by the Central Federation of Finnish Real Estate Agencies. The data represents occurred transactions between 1999 and 2018. The study discovers that a wooden structure has a positive price effect in the Helsinki metropolitan region suggesting an economically feasible opportunity to create low carbon urban housing. In the city of Helsinki, the effect is statistically significant (+8.85%) whereas no significance is found in either Espoo or Vantaa. The results suggest that in Helsinki, a direct financial benefit exists for both the city and private developers. For other cities, the study encourages the increase of consumption of wood due to its environmental properties. The study implies that wooden construction is an economically feasible solution in mitigating climate change. As this may provoke an increased demand for wood in construction, further research should be conducted to analyse its effects on the economy and the environment.
Portraits, Facial Perception, and Aspect-Seeing
Authors: Vrahimis Andreas 
Published: May 2021

Abstract
Is there a substantial difference between a portrait depicting the sitter’s face made by an artist and an image captured by a machine able to simulate the neuro-physiology of facial perception? Drawing on the later Wittgenstein, this paper answers this question by reference to the relation between seeing a visual pattern as (i) a series of shapes and colours, and (ii) a face with expressions. In the case of the artist, and not of the machine, the portrait’s creative process involves the ability to see both aspects. From the perspective of the image’s viewer, the distinction is more difficult to draw. I address this difficulty by further distinguishing between two attributes of portraits: their representational accuracy, and their ability to convey the artist’s reflection on her experience of seeing the sitter face-to-face. While artificial intelligence can mimic this latter reflective ability, it cannot exactly reproduce it.
Lowering the density: ants associated with the myrmecophyteTillandsia caput-medusaediminish the establishment of epiphytes
Authors: Vergara-Torres Carmen Agglael , Díaz-Castelazo Cecilia , Toledo-Hernández Víctor Hugo , Flores-Palacios Alejandro 
Published: May 2021

AbstractAnts benefit myrmecophytic plants by two main activities defending them from herbivores and offering nutrients. Ants’ territorial defence behaviour also benefits their myrmecophytic plants; in the case of trees, this behaviour includes eliminating structural parasites (epiphytes and lianas). These benefits could also occur with myrmecophytic epiphytes by decreasing the abundance of competing epiphytes. In two subunits of a tropical dry forest in the centre of Mexico, we (i) recorded the diversity of ants associated with the myrmecophyte Tillandsia caput-medusae, and experimentally tested: (ii) the effect of the ants associated with the myrmecophyte in the removal of its seeds and the seeds of other sympatric non-myrmecophyte species of Tillandsia; and (iii) if seed remotion by ants corresponds with epiphyte load in the preferred (Bursera copallifera) and limiting phorophyte species (B. fagaroides, Ipomoea pauciflora and Sapium macrocarpum). In five trees per species, we tied seed batches of T. caput-medusae, T. hubertiana, T. schiedeana and T. recurvata. One seed batch was close, and the other far away from a T. caput-medusae with active ants. Between forest subunits, ant richness was similar, but diversity and evenness differed. Ants diminish seed establishment of all the Tillandsia species; this effect is stronger in the forest subunit with a large ant diversity, maybe because of ant competition. Seed remotion by ants is independent of phorophyte species identity. Although ants can provide benefits to T. caput-medusae, they also could be lowering their abundance.
The Second of Two One-Year, Multicenter, Open-Label, Repeat-Dose, Phase II Safety Studies of PrabotulinumtoxinA for the Treatment of Moderate to Severe Glabellar Lines in Adult Patients
Authors: Lorenc Z Paul , Adelglass Jeffrey M , Avelar Rui L , Baumann Leslie , Beer Kenneth R , Cohen Joel L , Cox Sue Ellen , Dayan Steven H , Dover Jeffrey S , Downie Jeanine B , Draelos Zoe Diana , Goldman Mitchel P , Gross John E , Joseph John H , Kaufman-Janette Joely , Moy Ronald L , Nestor Mark , Schlessinger Joel , Smith Stacy R , Weiss Robert A 
Published: May 2021

Abstract

Background
PrabotulinumtoxinA is a 900-kDa botulinum toxin type A produced by Clostridium botulinum.

Objectives
The authors sought to investigate the safety of prabotulinumtoxinA for treatment of glabellar lines.

Methods
This was a multicenter, open-label, repeat-dose, 1-year phase II safety study. Adults with moderate to severe glabellar lines at maximum frown, as independently assessed by both investigator and patient on the validated 4-point photonumeric Glabellar Line Scale (0 = no lines, 1 = mild, 2 = moderate, 3 = severe), were enrolled. On day 0, patients received an initial treatment (IT) of 20 U prabotulinumtoxinA (4 U/0.1 mL final vacuum-dried formulation injected into 5 glabellar sites). On and after day 90, patients received a repeat treatment (RT) if their Glabellar Line Scale score was ≥2 at maximum frown by investigator assessment. Safety outcomes were evaluated throughout the study.

Results
The 570 study patients received a median total dose of 60 U, that is, 3 treatments. Sixty-one patients (10.7%) experienced adverse events (AEs) assessed as possibly study drug related; 6.5% experienced study drug–related AEs after the IT. With each RT, progressively lower percentages of patients experienced study drug–related AEs. Eight patients (1.4%) experienced study drug–related AEs of special interest: 5 experienced eyelid ptosis (0.9%), 3 eyebrow ptosis (0.5%), 1 blepharospasm (0.2%), and 1 blurred vision (0.2%). Seven patients (1.2%) experienced serious AEs, but none were study drug related. A total of 4060 serum samples were tested for antibotulinum toxin antibodies; no seroconversion was observed.

Conclusions
The safety of RTs of 20 U of prabotulinumtoxinA for moderate to severe glabellar lines was confirmed in this second phase II study based on a broad range of outcomes.

Level of Evidence: 2
Characterization of a novel moderate-substrate specificity amino acid racemase from the hyperthermophilic archaeon Thermococcus litoralis
Authors: Kawakami Ryushi , Kinoshita Chinatsu , Kawase Tomoki , Sato Mikio , Hayashi Junji , Sakuraba Haruhiko , Ohshima Toshihisa 
Published: May 2021

ABSTRACT
The amino acid sequence of the OCC_10945 gene product from the hyperthermophilic archaeon Thermococcus litoralis DSM5473, originally annotated as γ-aminobutyrate aminotransferase, is highly similar to that of the uncharacterized pyridoxal 5ʹ-phosphate (PLP)-dependent amino acid racemase from Pyrococcus horikoshii. The OCC_10945 enzyme was successfully overexpressed in Escherichia coli by coexpression with a chaperone protein. The purified enzyme demonstrated PLP-dependent amino acid racemase activity primarily toward Met and Leu. Although PLP contributed to enzyme stability, it only loosely bound to this enzyme. Enzyme activity was strongly inhibited by several metal ions, including Co2+ and Zn2+, and nonsubstrate amino acids such as l-Arg and l-Lys. These results suggest that the underlying PLP-binding and substrate recognition mechanisms in this enzyme are significantly different from those of the other archaeal and bacterial amino acid racemases. This is the first description of a novel PLP-dependent amino acid racemase with moderate substrate specificity in hyperthermophilic archaea.
TSSFinder—fast and accurateab initioprediction of the core promoter in eukaryotic genomes
Authors: de Medeiros Oliveira Mauro , Bonadio Igor , Lie de Melo Alicia , Mendes Souza Glaucia , Durham Alan Mitchell 
Published: May 2021

AbstractPromoter annotation is an important task in the analysis of a genome. One of the main challenges for this task is locating the border between the promoter region and the transcribing region of the gene, the transcription start site (TSS). The TSS is the reference point to delimit the DNA sequence responsible for the assembly of the transcribing complex. As the same gene can have more than one TSS, so to delimit the promoter region, it is important to locate the closest TSS to the site of the beginning of the translation. This paper presents TSSFinder, a new software for the prediction of the TSS signal of eukaryotic genes that is significantly more accurate than other available software. We currently are the only application to offer pre-trained models for six different eukaryotic organisms: Arabidopsis thaliana, Drosophila melanogaster, Gallus gallus, Homo sapiens, Oryza sativa and Saccharomyces cerevisiae. Additionally, our software can be easily customized for specific organisms using only 125 DNA sequences with a validated TSS signal and corresponding genomic locations as a training set. TSSFinder is a valuable new tool for the annotation of genomes. TSSFinder source code and docker container can be downloaded from http://tssfinder.github.io. Alternatively, TSSFinder is also available as a web service at http://sucest-fun.org/wsapp/tssfinder/.
Cost-Effectiveness of 1-Time Universal Screening for Chronic Hepatitis B Infection in Adults in the United States
Authors: Toy Mehlika , Hutton David , Harris Aaron M , Nelson Noele , Salomon Joshua A , So Samuel 
Published: May 2021

AbstractBackgroundAn estimated 862 000 to 2.4 million people have chronic hepatitis B infection (CHB). Hepatitis B screening is recommended for pregnant women and populations with increased CHB risk. However, diagnosis rates remain low, with only 33% of people with CHB aware of their infection. This study aimed to assess the cost-effectiveness of universal adult screening for CHB.MethodsWe used a Markov model to calculate the costs, population health impact, and cost-effectiveness of 1-time universal screening and CHB monitoring and treatment compared with current practice. Sensitivity analysis was performed on model parameters to identify thresholds for cost-saving or cost-effectiveness based on a willingness to pay of $50 000/quality-adjusted life-year. The analysis assumed testing would be performed during routine healthcare visits and that generic tenofovir or entecavir would be dispensed for treatment. Testing costs were based on Medicare reimbursement rates.ResultsAt an estimated 0.24% prevalence of undiagnosed CHB, universal hepatitis B surface antigen (HBsAg) screening in adults aged 18–69 years is cost-saving compared with current practice if antiviral treatment drug costs remain below $894/year. Compared with current practice, universal screening would avert an additional 7.4 cases of compensated cirrhosis, 3.3 cases of decompensated cirrhosis, 5.5 cases of hepatocellular carcinoma, 1.9 liver transplants, and 10.3 hepatitis B virus–related deaths at a saving of $263 000/100 000 adults screened.ConclusionsUniversal HBsAg screening of adults in the US general population for CHB is cost-effective and likely cost-saving compared with current CHB screening recommendations.
Using a Community-Based Participatory Research Model to Encourage Parental Involvement in Their Children’s Schools
Authors: Keller JoDee G , Miller Claudia , LasDulce Chance , Wohrle Rachel G 
Published: May 2021

AbstractParental engagement with their children’s education has been shown to have positive effects for children’s academic outcomes; thus, learning ways to increase parental engagement can be beneficial for students. Because of the importance of understanding schools in the context of the community and the essential role that community can play in supporting schools, community-based participatory research (CBPR) may be a particularly effective approach to data collection because it engages community partners as well as parents and school personnel, and it gains information that leads to meaningful interventions. This study explored the use of CBPR within an economically and ethnically diverse school community with the intent of developing strategies to foster increased parental participation in their children’s education. Social workers and social work students facilitated focus groups with parents and community stakeholders to explore ways to increase parental engagement in their children’s school and to identify barriers to engagement. The article identifies next steps based on the recommendations of participants and describes the outcomes of preliminary implementation of these steps.
Certification and Professional Preparation of School Social Workers, School Psychologists, and School Counselors
Authors: Mitchell Brandon , Frey Andy , Kelly Michael S 
Published: May 2021

Abstract
Educational leaders are faced with the difficult task of providing optimal services to all students. Among their many challenges is to choose between a variety of professionals whose mission is to improve outcomes by addressing largely nonacademic risk factors that affect students’ ability to benefit from their educational experiences. Specialized instructional support personnel are often hired to help remove barriers to learning and improve student outcomes; however, certification requirements for these professionals vary by discipline and state. The purpose of this article is to replicate Altshuler and Webb's analysis of certification requirements for school social workers, school psychologists, and school counselors. To do so, the authors adopted a comparative case study approach to collect, identify, compare, and contrast extant documents related to state certification, including degree, education-specific coursework, practicum/internship experiences, and examination requirements. Results indicate that although school social work certification has become more rigorous, its requirements remain more varied across all categories reviewed compared with those for school psychologists and school counselors. The article concludes with recommendations for practice, policy, and research.
Seasonal metabolic flexibility is correlated with microclimate variation in horned larks and house sparrows
Authors: Oboikovitz Paige , Swanson David L 
Published: May 2021

Abstract
Maximum and minimum metabolic rates in birds are flexible traits and such flexibility can be advantageous in variable climates. The climatic variability hypothesis (CVH) posits that more variable climates should result in greater metabolic flexibility for geographically distinct populations. Whether the CVH applies to sympatric species occupying microclimates differing in variability is unknown. Microclimates of open habitats are likely more variable than those of sheltered habitats. If the CVH extends to microclimates, we expect birds from open habitats to show greater flexibility than those from sheltered habitats. To test this extension of the CVH, we compared seasonal variation in microclimates and metabolic rates for sympatric horned larks Eremophila alpestris, which occupy open habitats, and house sparrows Passer domesticus, which occupy sheltered habitats. We measured operative temperature (Te, an integrative measure of the thermal environment), summit metabolic rate (Msum, maximal cold-induced metabolic rate), and basal metabolic rate (BMR, minimal maintenance metabolic rate) in summer and winter. For both winter and summer, daily minimum Te was similar between open and sheltered habitats but maximum Te was higher for open habitats. Winter microclimates, however, were colder for open than for sheltered habitats after accounting for convective differences. Both species increased Msum in winter, but seasonal Msum flexibility was greater for larks (43%) than for sparrows (31%). Winter increases in BMR were 92.5% and 11% for larks and sparrows, respectively, with only the former attaining statistical significance. Moreover, species * season interactions in general linear models for whole-organism metabolic rates were significant for BMR and showed a similar, although not significant, pattern for Msum, with greater seasonal metabolic flexibility in horned larks than in house sparrows. These results suggest that extending the CVH to sympatric bird species occupying different microclimates may be valid.
Reading Achievement of Deaf Students: Challenging the Fourth Grade Ceiling
Authors: Mayer Connie , Trezek Beverly J , Hancock Gregory R 
Published: May 2021

AbstractHistorically it has been reported that deaf students do not achieve age-appropriate outcomes in reading, with this performance often being characterized in terms of a fourth grade ceiling. However, given the shifts in the field during the past 20 years (e.g., widespread implementation of newborn hearing screening, advances in hearing technologies), it would be timely to question whether this continues to serve as a meaningful benchmark. To this end, the purpose of this study was to investigate reading outcomes of a Canadian cohort of school-aged deaf learners (N = 70) who all used listening and spoken language as the primary mode of communication. Specifically, the goal was to establish whether their achievement approached that of their hearing age peers and to identify demographic factors influencing performance (i.e., gender, unilateral/bilateral hearing loss, personal amplification, level of auditory functioning, grade placement, additional disabilities, home language). Results indicate that participants obtained standard scores in the average range on both the Basic Reading and Reading Comprehension clusters of the Woodcock Johnson III-Diagnostic Reading Battery (Woodcock et al., 2004), surpassing the fourth grade reading achievement ceiling often reported for this population.