bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relay oral therapy in febrile urinary tract infections caused by extended spectrum beta-lactamase–producing Enterobacteriaceae in children: A French multicenter study
Authors: Lignieres Gabriel , Birgy André , Jung Camille , Bonacorsi Stéphane , Levy Corinne , Angoulvant François , Grimprel Emmanuel , Dommergues Marie Aliette , Gillet Yves , Craiu Irina , Rybak Alexis , De Pontual Loic , Dubos François , Cixous Emmanuel , Gajdos Vincent , Pinquier Didier , Andriantahina Isabelle , Soussan-Banini Valérie , Georget Emilie , Launay Elise , Vignaud Olivier , Cohen Robert , Madhi Fouad 
Published: September 2021

ObjectivesWe need studies assessing therapeutic options for oral relay in febrile urinary tract infection (FUTI) due to ESBL–producing Enterobacteriaceae (ESBL-E) in children. Amoxicillin-clavulanate/cefixime (AC-cefixime) combination seems to be a suitable option. We sought to describe the risk of recurrence at 1 month after the end of treatment for FUTI due to ESBL-E according to the oral relay therapy used.Materials and methodsWe retrospectively identified children <18 years who were included in a previous prospective observational multicentric study on managing FUTI due to ESBL-E between 2014 and 2017 in France. We collected whether children who received cotrimoxazole, ciprofloxacin or the AC-cefixime combination as the oral relay therapy reported a recurrence within the first month after the end of treatment. Then, we analyzed the susceptibility drug-testing of the strains involved.ResultsWe included 199 children who received an oral relay therapy with cotrimoxazole (n = 72, 36.2%), ciprofloxacin (n = 38, 19.1%) or the AC-cefixime combination (n = 89, 44.7%). Nine (4.5%) patients had a recurrence within the first month after the end of treatment, with no difference between the 3 groups of oral relay (p = 0.8): 4 (5.6%) cotrimoxazole, 2 (5.3%) ciprofloxacin and 3 (3.4%) AC-cefixime combination. Phenotype characterization of 249 strains responsible for FUTI due to ESBL-E showed that 97.6% were susceptible to the AC-cefixime combination.ConclusionsThe AC-cefixime combination represents an interesting therapeutic option for oral relay treatment of FUTI due to ESBL-E as the recurrence rate at 1 month after the end of treatment was the same when compared to cotrimoxazole and ciprofloxacin.
Accuracy of perceived glaucoma risk by patients in a clinical setting
Authors: Hou Chiun-Ho , Lee Jiahn-Shing , Lin Ken-Kuo , Liu Laura , Lee Yung-Sung , Pu Christy 
Published: September 2021

ObjectiveTo determine whether patients attending the ophthalmology department underestimate their glaucoma risks.MethodWe conducted a cross-sectional survey with a final study population of 1203 individuals from two medical centers in Taiwan during January 1–June 30, 2019. The “High concern” group was defined as the set of patients who rated themselves as having low risk but who had been rated by physicians as having medium or high risk of developing glaucoma over the next year.ResultsApproximately 12% of the respondents belonged to the “High concern” group. For those with education at the college level or higher, the interaction term was estimated to be 0.294 (95% CI = 0.136–0.634). Marginal effect calculations revealed significant sex-based differences in the effect of knowledge at specific age intervals.ConclusionsA considerable proportion of patients attending the ophthalmology department underestimate their glaucoma risks. Misjudgment of glaucoma risks can lead to delays in seeking of medical attention. Glaucoma education should be designed according to each patient’s education level and sex, as its effect is not consistent across different education and sex clusters.
Pilot study on the value of Raman spectroscopy in the entity assignment of salivary gland tumors
Authors: Meyer Till Jasper , Gerhard-Hartmann Elena , Lodes Nina , Scherzad Agmal , Hagen Rudolf , Steinke Maria , Hackenberg Stephan 
Published: September 2021

Background
The entity assignment of salivary gland tumors (SGT) based on histomorphology can be challenging. Raman spectroscopy has been applied to analyze differences in the molecular composition of tissues. The aim of this study was to evaluate the suitability of RS for entity assignment in SGT.

Methods
Raman data were collected in deparaffinized sections of pleomorphic adenomas (PA) and adenoid cystic carcinomas (ACC). Multivariate data and chemometric analysis were completed using the Unscrambler software.

Results
The Raman spectra detected in ACC samples were mostly assigned to nucleic acids, lipids, and amides. In a principal component-based linear discriminant analysis (LDA) 18 of 20 tumor samples were classified correctly.

Conclusion
In this proof of concept study, we show that a reliable SGT diagnosis based on LDA algorithm appears possible, despite variations in the entity-specific mean spectra. However, a standardized workflow for tissue sample preparation, measurement setup, and chemometric algorithms is essential to get reliable results.
The Photoromance: A Feminist Reading of Popular Culture, Paola Bonifazio (2020)1
Authors: Buonanno Milly 
Published: September 2021

Review of: The Photoromance: A Feminist Reading of Popular Culture, Paola Bonifazio (2020)
Cambridge: MIT Press, 248 pp.,
ISBN 978-0-26253-923-9, p/bk, $29.95
Viaggio sulla luna: Voyage dans la Lune (Georges Méliès, 1902), Antonio Costa (2013)
Cabiria: (Giovanni Pastrone, 1914). Lo spettacolo della Storia, Silvio Alovisio (2014)
Ma l’amor mio non muore! (Mario Camerini, 1913): La diva e l’arte di comporre lo spazio, Stella Dagna (2014)
La presa di Roma - 20 Settembre 1870 (Filoteo Alberini, 1905): La nascita di una nazione, Giovanni Lasi (2015)
I topi grigi: (Emilio Ghione, 1918) Il romanzo cinematografico di Za la Mort, Denis Lotti (2018)
Authors: Bertellini Giorgio 
Published: September 2021

Review of: Viaggio sulla luna: Voyage dans la Lune (Georges Méliès, 1902), Antonio Costa (2013)
Milan: Mimesis, 120 pp.,
ISBN 978-8-85751-624-0, p/bk, €10.00

Cabiria: (Giovanni Pastrone, 1914). Lo spettacolo della Storia, Silvio Alovisio (2014)
Milan: Mimesis, 114 pp.,
ISBN 978-8-85752-157-2, p/bk, €8.00

Ma l’amor mio non muore! (Mario Camerini, 1913): La diva e l’arte di comporre lo spazio, Stella Dagna (2014)
Milan: Mimesis, 96 pp.,
ISBN 978-8-85752-296-8, p/bk, €8.00

La presa di Roma - 20 Settembre 1870 (Filoteo Alberini, 1905): La nascita di una nazione, Giovanni Lasi (2015)
Milan: Mimesis, 108 pp.,
ISBN: 978-8-85753-048-2, p/bk, €9.00

I topi grigi: (Emilio Ghione, 1918) Il romanzo cinematografico di Za la Mort, Denis Lotti (2018)
Milan: Mimesis, 98 pp.,
ISBN 978-8-85755-214-9, p/bk, €9.00
Genome-wide polygenic analysis of multiple sclerosis markers
Authors: Timasheva Ya. R. , Nasibullin T. R. , Tuktarova I. A. , Erdman V. V. , Galiullin T. R. , Zaplakhova O. V. , Bakhtiiarova K. Z. 
Published: September 2021

Objective: to perform a genome-wide polygenic analysis of multiple sclerosis (MS) markers in the ethnic groups of Bashkirs, Russians, and Tatars living in the Republic of Bashkortostan (Russian Federation).Patients and methods. Genotyping was performed using allele-specific polymerase chain reaction (PCR) and PCR-restriction fragment length polymorphism analysis of genes of the human leukocyte differentiation antigens CD6 (rs17824933), CD40 (rs6074022), CD58 (rs2300747), CD86 (rs9282641), transcription factors SOX8 (rs2744148) and ZBTB46 (rs6062314), beta-mannosidase MANBA (rs228614), C-type lectin domain CLEC16A (rs12708716), ribosomal protein S6 kinase B1 RPS6KB1 (rs180515), and long noncoding RNA gene PVT1 (rs759648) in 644 patients with MS and 1408 controls. Multilocus analysis of the disease associations with combinations of genotypes and alleles of the studied polymorphic loci was performed using the APSampler algorithm.Results and discussion. We determined the distribution of genotype and allele frequencies of the studied polymorphic loci in the ethnic groups of Bashkirs, Russians, and Tatars. We also observed disease associations with CD58 (rs2300747) and RPS6KB1 (rs180515) polymorphic loci in Russian men, CD86 (rs9282641) in Russian, PVT1 (rs759648) in Tatar women, CD40 (rs6074022) in Bashkir men, and identified 19 combinations of genotypes and/or alleles significantly associated with MS.Conclusion. Based on the genome-wide polygenic analysis of MS markers, we identified ethno- and gender-specific combined markers of the disease susceptibility.
Enhanced shuffled frog leaping algorithm with improved local exploration and energy-biased load reduction phase for load balancing of gateways in WSNs
Authors: Adamuthe Amol , Pathan Abdulhameed 
Published: September 2021

AbstractWireless sensor networks (WSNs) have grown widely due to their application in various domains, such as surveillance, healthcare, telecommunication, etc. In WSNs, there is a necessity to design energy-efficient algorithms for different purposes. Load balancing of gateways in cluster-based WSNs is necessary to maximize the lifetime of a network. Shuffled frog leaping algorithm (SFLA) is a popular heuristic algorithm that incorporates a deterministic approach. Performance of any heuristic algorithm depends on its exploration and exploitation capability. The main contribution of this article is an enhanced SFLA with improved local search capability. Three strategies are tested to enhance the local search capability of SFLA to improve the load balancing of gateways in WSNs. The first proposed approach is deterministic in which the participation of the global best solution in information exchange is increased. The next two variations reduces the deterministic approach in the local search component of SFLA by introducing probability-based selection of frogs for information exchange. All three strategies improved the success of local search. Second contribution of article is increased lifetime of gateways in WSNs with a novel energy-biased load reduction phase introduced after the information exchange step. The proposed algorithm is tested with 15 datasets of varying areas of deployment, number of sensors and number of gateways. Proposed ESFLA-RW variation shows significant improvement over other variations in terms of successful local explorations, best fitness values, average fitness values and convergence rate for all datasets. Obtained results of proposed ESFLA-RW are significantly better in terms of network energy consumption, load balancing, first gateway die and network life. The proposed variations are tested to check the effect of various algorithm-specific parameters namely frog population size, probability of information exchange and probability of energy-biased load reduction phase. Higher population size and probabilities give better solutions and convergence rate.
Commercial building load characteristics modeling considering equipment innate laws and various staff behaviors under demand response mechanism
Authors: Liu Xiaoou 
Published: September 2021

Abstract
At present, the traditional load model relies on a large number of historical data, ignoring the relationship between load demand and user behavior and the temporal and spatial distribution of load. To solve this problem, this paper proposes a modeling method of energy consumption characteristics of commercial office building considering the physical characteristics of energy consuming equipment and staff behavior factors. Firstly, the load of commercial office building is classified based on user behavior. Secondly, according to the proposed load classification method, a time distribution model associated with user behavior is established for each type of load energy consumption equipment, and the total load model of commercial office building is obtained. On this basis, the proposed model is expanded in both time and space, so that the total load model of commercial office building can be used to analyze energy consumption in different time scales and different regional areas. Through the combination of non-intrusive load decomposition and Markov chain, the energy consumption behavior of users is analyzed and simulated, and a refined load forecasting method of commercial office building considering equipment and user behavior under demand response mechanism is proposed. Finally, the example analysis shows that the proposed method can no longer depend on huge amounts of similar data for driving, can effectively reduce the impact of the original data on the load feature extraction, and has the ability to achieve load forecasting independently.
The diagnostic and prognostic value of miR-92a in gastric cancer: A systematic review and meta-analysis
Authors: Guo Hanxu , Wang Yuhang , Wang Zhicheng , Wang Zishu , Xue Sheng 
Published: September 2021

Abstract

Background
miR-92a is believed to have a significant role in the diagnosis and prognosis of different types of tumors, but the potential impact of its expression is still controversial due to the sample size. We conducted the meta-analysis to figure out whether miR-92a could be used as a detecting tool for assessing the prognosis of gastric cancer.

Method
A literature search was conducted by retrieving the Web of Science, PubMed, EMBASE, Chinese National Knowledge Infrastructure, VIP (Technology of Chongqing databases), and Wanfang databases (last updated by February 2020). The sensitivity (SEN), specificity (SPE), positive and negative likelihood ratios (PLR and NLR), diagnostic odds ratio (DOR), and area under the ROC curve (AUC) were pooled to explore the diagnostic performance of miR-92a. The pooled hazard ratios (HRs) and 95% CIs of miR-92a for overall survival (OS) were calculated to explore the prognostic performance of miR-92a.

Results
Nine articles containing 11 studies were included. The pooled SEN and SPE were 0.76 and 0.79. Besides, the pooled PLR and NLR were 3.7 and 0.30, and the pooled DOR was 12. AUC was 0.84, indicating a significant value of miR-92a in gastric cancer detection. For the prognostic analysis of miR-92a in gastric cancer, the univariate and multivariate data’s poor OS were 1.37 and 2.01.

Conclusion
The present meta-analysis demonstrated that miR-92a could be a potential biomarker for the detection of gastric cancer. miR-92a could also be used as a valuable indicator for predicting the prognosis of gastric cancer patients.
Ways to achieve efficient non-local vortex beam generation
Authors: Liu Wenzhe , Shi Lei , Zi Jian , Chan Che Ting 
Published: September 2021

Abstract
Based on the insights into the phenomenon of bound states in the continuum, a novel approach utilizing the momentum-space polarization morphologies of periodic structures to generate vortex beams (VBs) has been proposed. Such periodic structures modulate beams in a nonlocal way and require no precise alignment. However, the efficiency of such an approach has not been analyzed in detail, and the efficiency in previous realizations is far from optimized. Here, we analyze the factors affecting the efficiency of nonlocal VB generation. We show that the maximal efficiency cannot exceed 25% if the periodic structure carries only singlet resonances. To go beyond this limit, we propose two approaches to improve efficiency. We theoretically analyze the mechanisms and verify the approaches by full-wave simulations. Both of the approaches serve to improve the generation efficiency by several folds.
Building effective core/shell polymer nanoparticles for epoxy composite toughening based on Hansen solubility parameters
Authors: Ning Na , Qiu Yiping , Wei Yi 
Published: September 2021

Abstract
Particles have been demonstrated to toughen epoxy resins, especially for fiber-reinforced epoxy composites, and core/shell particles are one of them. It is known that not all particles toughen the same but most evaluations are through experimentation, and few studies have been conducted to accurately predict the particles’ toughening effect or guide the design of effective particles. In this study, efforts were made to find the control factors of core/shell particles, primarily interfacial compatibility and degree of dispersion, and how to predict them. Nanocomposites were fabricated by incorporating core/shell nanoparticles having various shell polymer compositions, especially their polarities. Their compatibility was estimated using a novel quantitative approach via adopting the theory of Hansen solubility parameters (HSP), in which the HSP of core/shell nanoparticles and the epoxy matrix were experimentally determined and compared. It was found that the HSP distance was a good predictor for particle dispersion and interfacial interaction. Particles having a small HSP distance (R
a) to the epoxy resin, represented by the polybutylacrylate core/polymethyl methacrylate shell particle having the smallest R
a of 0.50, indicated a uniform dispersion and strong interfacial bonding with the matrix and yielded outstanding toughening performance. In contrast, polybutylacrylate core/polyacrylonitrile shell particle having the largest HSP distance (6.56) formed aggregates and exhibited low interfacial interaction, leading to poor toughness. It was also demonstrated that HSP can provide an effective strategy to facilitate the design of effective core/shell nanoparticles for epoxy toughening.
A preliminary analysis of intonation patterns in Ecuadorian Cuencano Spanish
Authors: Portocarrero Alex , Stewart Jesse 
Published: September 2021

AbstractEl Cantado Cuencano“Cuencano singing” constitutes the hallmark of Cuencano Spanish: a widely spoken Andean dialect in the Ecuadorian province of Azuay. This colloquially described “singing” makes Cuencano Spanish one of the most distinct dialects of Ecuador. The aim of the present study is to provide a preliminary analysis of intonation patterns from common utterance types in this under documented dialect. A sample of 550 utterances from 11 categories that included declarative statements, yes/no questions, exclamative statements, wh-questions, imperatives, lists, conditionals, tag-questions, interjections, negative statements, and vocatives was collected from five male and five female participants. The tokens were analyzed acoustically and labeled using the Spanish Tones and Break Indices system (Sp_ToBI). Results reveal the presence of a tritonal pitch accent (PA), labeled as L + H* + L and the extensive use of bitonal PAs (namely, L + H*). These three phenomena mark the singing quality of Cuencano Spanish and make it stand out from the dialects of Ecuadorian Spanish.
Investigation of RASSF4 gene in head and neck cancers
Authors: Karagedik Emine H. , Pamuk Saim , Ataş Merve N. , Ulusan Murat , Aydemir Levent , Ergen Arzu 
Published: September 2021

Abstract

Objectives
RASSF gene family can inhibit the growth of RAS oncogene. This gene family is suggested to have a role in cell cycle control, apoptosis, cell migration, and mitosis control. This study evaluated RASSF4 gene expression levels, SNPs and serum levels in tissues dissected from both healthy individuals and patients diagnosed with head, and neck cancer.

Methods
RASSF4 gene expression levels were determined using the RT-PCR. Serum levels of RASSF4 were tested using the Enzyme-Linked Immuno Sorbent Assay technique in study groups. RASSF4 rs7896801 and rs884879 genotypes were identified using by the RT-PCR.

Results
No statistical difference was observed between study groups according to RASSF4 gene expression levels. According to SNP results, rs7896801 revealed a 2.4 fold increase of G-allele presence in patients (p=0.015). The increase in the presence of AA genotype was statistically significant for the control group (p=0.015). Distribution of genotypes and alleles for rs884879 showed a 2.2 fold increase in CC genotype for healthy group (p=0.031) however, the presence of T allele showed a significant increase in the patients (p=0.048).

Conclusions
We suggest that this study will play a pioneering role for the next studies on RASSF4 gene, especially on SNPs.
Low-perchlorate blue-flame pyrotechnic compositions
Authors: Juknelevicius Dominykas , Webb Rutger , Klapötke Thomas M. , Ramanavicius Arunas 
Published: September 2021

Abstract
An ammonium perchlorate (AP) and copper(II) benzoate pyrotechnic blue-flame composition was gradually “diluted” by adding an experimental perchlorate-free blue-flame composition based on aminoguanidinium nitrate (AGN), malachite, PVC powder and shellac resin. Flame’s luminous intensity and specific luminous intensity were recorded and analyzed. A copper-aminoguanidinium (CuAG) complex was also synthesized and tested as an energetic additive in perchlorate-free blue-flame composition. Green-flame color was observed when testing chlorine-free energetic compositions with CuAG.
The ionic conductivity of alkali aluminum germanium phosphate glasses – comparison of Plasma CAIT with two electrode DC measurements
Authors: Wiemer Jan L. , Rein Kevin , Weitzel Karl-Michael 
Published: September 2021

AbstractThe ionic conductivity of alkali aluminum germanium phosphates (MAGP) has been investigated by two different techniques, i.) a fs-Plasma-Charge Attachment Induced Transport (CAIT) approach and ii.) a classical two electrode DC approach. Amorphous MAGP samples of the composition M1.5Al0.5Ge1.5(PO4)3M=(Li–Cs) have been synthesized by the melt-quenching technique. Comparison of fs-Plasma-CAIT and DC data reveal that the ionic conductivities as well as the activation energies for ion transport agree within the error margins of the experiment. While conventional expectation suggests that a DC approach should fail because of spontaneous charge carrier blocking, this work demonstrates that DC measurements are a simple tool for quantifying ionic conductivities provided that only a small amount of charge has been transported in total.
Influence of Piston Friction on Resilient Modulus of Subgrade Soil
Authors: Yang Shu-Rong 
Published: September 2021

Abstract
The repeated load triaxial test has been commonly used to evaluate the resilient modulus of base, subbase, and subgrade soils. When conducting the resilient modulus test, if a load cell is placed outside the chamber to measure the axial load, the piston friction is included in the axial load, resulting in inaccuracy on the resilient modulus. Hence, piston friction needs correcting prior to the resilient modulus test when using the external load cell to measure the axial load. In this study, quasi-static and dynamic corrections of the piston friction were conducted under various displacement rates and confining pressures. Test results indicate that the piston friction increases with increasing confining pressure. A correlation model between the piston friction and the confining pressure was established. Besides, the influences of piston friction on the resilient modulus of A-7-5 soil compacted at the optimum moisture content were evaluated. Test findings demonstrate that the resilient modulus is overestimated when ignoring the piston friction, especially at low deviator stress. Procedures for the correction of the piston friction were established and presented.