bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neotropical Ostracode Oxygen and Carbon Isotope Signatures - Implications for Calcification Conditions
Authors: Wrozyna Claudia ,   Juliane Meyer2,   Martin Dietzel3,   Werner E. Piller4
Published: August 2021

Abstract

Calcitic valves of non-marine ostracodes are important geochemical archives. Investigations of the relationship between the isotopic ranges of modern ostracode populations and their host water provide important information on local or regional conditions and influences. Here we present the first δ18Oostracode and δ13Costracode dataset of the freshwater ostracode species Cytheridella ilosvayi along with characterization of the precipitating water - chemical composition, δDwater, δ18Owater, δ13CDIC values - covering a large geographical range (Florida to Brazil). With this data we extended a newly developed approach based on the estimation of δ18O values of monthly equilibrium calcites as references for the interpretation of δ18Oostracode values.The expected apparent oxygen isotope fractionation between CaCO3 - and H2O is correlated with temperature with smaller values occurring at higher temperatures as valid at isotope equilibrium (δ18Ocalcite_eq). Additional to a species-specific offset, unusual high deviations of δ18Oostracode vs. δ18Owater values most likely reflect the time lag between valve calcification and sampling. Coincidence between δ18Oostracode and δ18Ocalcite_eq is restricted to few months indicating a seasonal calcification of Cytheridella. There is a characteristic pattern in its difference between mean δ18Oostracode and δ18Ocalcite_eq which implies that Cytheridella provides a synchronous life cycle in its geographical range with two calcification periods in spring (May, June) and autumn (October). This ubiquitous life cycle of Cytheridella in the entire study area is considered to be phylogenetically inherited. It might have originally been adapted to environmental conditions but has been conserved during the migration and radiation of the group over the Neotropical realm.
Long-term Health Benefits to Newly Diagnosed Type-2 Diabetes from Short-term Continuous-subcutaneous Insulin Injection Therapy
Authors: Zhang Wanjun , KE Weijian , HE Qun , Bian Qiao , GUO Huijie , LIU Liehua , ZHENG Dantong , LI Yanbing , XIA Yinghua 
Published: August 2021

Abstract
BackgroundContinuous-subcutaneous insulin injection (CSII) therapy to type 2 diabetes mellitus (T2DM) patients generated short-term health benefits. Our aims were to investigate long-term health benefits of CSII monotherapy, in combination with metformin and pioglitazone, or with sitagliptin. MethodsIn this randomized clinical trial, patients were treated for around 90 days and were monitored for one year. Demographic and laboratory data were analysed using the UKPDS_OM2 program to estimate 20-year health benefits. Multiple linear regression model was used to identify factors associated with changes of each health benefit.ResultsFor the 134 treated patients, most health benefit indicators were improved significantly, except for renal failure. For example, life expectancies increased by 0.41±0.48 year and quality-adjusted life expectancy (QALE) by 0.45±0.46 year (p<0.001). Reductions in 20-year risk were: amputation by 70.6%, ulcer 66.7%, blindness 57.1%, stroke 45.5%, myocardial infarction 43.5%, all-causes of death 20.5%, ischaemic heart disease 6.7%, with heart failure < 0.1%. However, no difference in benefits was found among the three therapeutic protocols. Health benefits were lower for older patients, for females in amputation and ulcer risk, and for smokers in blindness risk. ConclusionsShort-term CSII therapy produced significant and multiple long-term health benefits (based on simulated risk analyses) to T2DM patients and benefits were modified by age, sex and smoking factors. The three therapeutic protocols produced the same benefits. Trial registration The clinical trial was registered in ClinicalTrials.gov on November 15, 2011, with the registration number: NCT01471808.
The Process of Regional Trauma System Development in Shenzhen, China: An 8-Year Journey
Authors: Zhang Guixi , Leung Gilberto Ka Kit , Lo Chung Mao , Lo Richard Kwong-Yin , Wong John , Maier Ronald Vitt , Bulger Eileen M. , Fan Joe King Man , Fu Xiaobing 
Published: August 2021

Abstract
Background: International experiences have shown that trauma system development significantly reduces preventable deaths and disabilities. During the 8-year study, the aim was to find solutions for trauma system development in Shenzhen, China, so as to reduce trauma mortality and morbidity. Methods: Introducing the ATLS® program to mainland China was started in 2013. A geospatial analysis of traumatic incidents was conducted in 2014. A regional trauma center was illustrated as an example to be used as a reference. The trauma audit meeting was introduced as an approach to continuous trauma quality improvement. The Shenzhen Trauma Surgery Committee was established to finalize the plan for designation of trauma care hospitals. The American College of Surgeons Trauma System Development Guidelines were translated into Chinese. Results: ATLS® provider course was held in Shenzhen and totally 205 doctors received training. A regional trauma center where adopted ATLS® principles as the standard for trauma resuscitation and early trauma care, with results showing significant improvements in trauma team organization, trauma resuscitation, definitive trauma care and a significant reduction in mortality among major trauma patients. The trauma audit meeting was introduced to 8 hospitals. A new trauma system plan for Shenzhen was set up and a consensus was reached on trauma center designation. The American College of Surgeons' “Resources for Optimal Care of the Injured Patient” was translated into Chinese and published in November 2020. Conclusion: The critical steps in establishing the framework for the Shenzhen trauma system included: geospatial analysis of traumatic incidents, trauma care training for providers, trauma center development, regional trauma center designation and development of trauma quality improvement programs. This practical approach can be replicated in other countries seeking to establish a trauma system. We are now working toward extension of this approach to other regions of mainland China.
Human Erythrocyte-Like Transformation of Synthetic Polymer Vesicles
Authors: Yoshida Eri 
Published: August 2021

Abstract
This paper describes that synthetic polymer vesicles undergo a human erythrocyte-like transformation in response to temperature changes. The normally biconcave discoid erythrocytes, i.e., the discocytes, are transformed into various shapes by their environmental stresses. Field emission scanning electron microscopy (FE-SEM) demonstrates that the spherical vesicles consisting of poly(methacrylic acid)-block-poly(n-butyl methacrylate-random-methacrylic acid), PMAA-b-P(BMA-r-MAA), transform into echinocyte-like crenate vesicles due to expansion by the component copolymers in being freed from the vesicle surface when heated in an aqueous methanol solution. An increase in the vesicle concentration transforms the spherical vesicles into stomatocyte-like cup-shaped vesicles via the membrane perforation or double invaginations followed by membrane coupling and fusion. Light scattering studies reveal the reversibility and repeatability of the transformations. These findings indicate that the erythrocyte transformations are attributed to the inherent property of the bilayer membrane. The polymer vesicles are helpful for a better understanding of the biomembrane.
Trends in COVID-19 Infected Cases and Deaths Based on Parametric and Nonparametric Regression Models
Authors: ARUNACHALAM RAJARATHINAM , PAKKIRISAMY TAMILSELVAN , Madhaiyan Ramji 
Published: August 2021

Abstract
The present investigation was carried out to study the trends in COVID-19 infected cases and deaths based on the parametric, exponential smoothing and non-parametric regression models by using COVID-19 cumulative infected cases and deaths due to infections The statistically most suited parametric models are selected based on the highest adjusted R2, significant regression co-efficient and co-efficient of determination (R2). Appropriate model is selected based on the model performance measures such as, Root Mean Square Error, Mean Absolute Error, Mean Absolute Percentage Error, assumptions of normality and independence of residuals. Nonparametric estimates of underlying growth functions are computed at each and every time points.
The cis-responsive element of Foot-and-mouth disease virus interacts with host cellular factor PCBP2 dependent on host specificity
Authors: Cheong JaeHun , Jang Jeong A , Ku Bok Kyung 
Published: August 2021

Abstract
I. Background: Foot-and-mouth disease virus (FMDV) is a highly contagious viral pathogen in cloven-hoofed animal including cattle and pig, yet progress in the molecular mechanisms of FMDV genome replication is notably lagging behind that for many RNA viruses. A positive single stranded RNA of FMDV encodes a single long open reading frame flanked by a long 5’-untranslated region (5’UTR) and a short 3’-UTR. The cis-responsive element (CRE) of 5’UTR is critical for FMDV genome replication. II. Methods and Results: Here, we described that poly(C)-binding protein 2 (PCBP2) is revealed as a CRE-binding cellular factor. The RNA immunoprecipitation experiment confirmed that the FMDV CRE interacts with PCBP2 protein. CRE derived from FMDV infection in pig bound stronger to PCBP2 protein of pig than cattle PCBP2, showing host specific RNA-protein interaction. In addition, PCBP2 interacts with FMDV 3B protein together with CRE. The interaction of PCBP and 3B protein with CRE also showed host-specific manners. III. Conclusions: These data suggest that cellular PCBP2 may serve as a host cellular factor of FMDV to facilitate viral replication through interaction with the viral genome and contribute to determine host susceptibility of FMDV variants. The inter-molecular interaction between cellular PCBP2 and FMDV 3B and CRE provides perspectives for antiviral strategy.
They forgot their “baby”?!: Factors that lead students to forget their cell phone
Authors: Rose Nathan , Doolen Abigail , O’Rear Andrea 
Published: August 2021

Abstract

Remembering intentions is critical for daily life, yet errors happen surprisingly often, even when there are fatal consequences, as in the “forgotten baby syndrome”. To study how people forget personally-important intentions, we took 192 students’ cell phones and attached an activity tracker to their clothes while they participated in an unrelated experiment in our lab. We examined how often students forgot to retrieve their cell phone (personally important task) and return the tracker (experimenter relevant task) when they left the lab, and whether it mattered if the instructions were explicitly encoded or not. Students only forgot the tracker 10-13% more often than their cell phone, and explicit instructions did not reduce forgetting; neither did longer, more distracting ongoing tasks. Between 60-70% of participants said the intention “popped into mind”. We suggest that PM intentions are “autonomically” encoded, yet even personally important tasks are forgotten at surprising rates.
Modelling Nigeria Male Mortality Using Functional Data Time Series Analysis Approach.
Authors: NDIKUBWIMANA Jean Bosco , F.K LAWAL , KARAMUZI James , DUKUNDE Angelique , GATABAZI Evariste , GASIGWA Joel , NGENDAHIMANA Frederic 
Published: August 2021

Abstract
Incidence and mortality rates are considered as a guideline for planning public health strategies and allocating resources. Several methods have been proposed and used for modeling mortalities of various countries. Among the leading mortality, models are the Lee-Carter model which has been used in various countries and adjudged to fit the mortality of these countries well. But it came with its own limitations as the model was used in a more developed nation. In this research work, we propose functional data analysis techniques to model Nigerian Male mortality using the data obtained from the Nigeria Bureau of Statistics from 1998-2010. We compared the results obtained using some parameters such as MAPE and MSE. From the results, we discovered that the improvement of the parameters of our model shows that it is better than the Lee-Carter model in analyzing Nigerian Male Mortality.
The Effect of Different Regimens of Vaccination against Pneumococcal Infection on the Clinical Course of Chronic Obstructive Pulmonary Disease: Focus on Changes in Sputum Microorganism Population
Authors: Kostinov M. P. , Protasov А. D. , Zhetkov А. V. , Shteyner M. L. , Tezikov Yu. V. , Lipatov I. S. 
Published: August 2021

The objective: development of the best vaccination regimen against pneumococcal infection in patients with chronic obstructive pulmonary disease (COPD) with consideration of changes in microbiological and clinical parameters.Subjects and Methods. 115 patients with COPD were randomized into 4 pneumococcal vaccination groups, they were examined and followed up for 4 years; 112 patients completed the study complying with the protocol. Detail medical history of all subjects was collected. To verify the diagnosis of COPD, all subjects underwent external respiratory function test and bronchodilator test (salbutamol, 400 μg) according to the standard method. The classic microbiological assessment was used in this study. The clinical effectiveness of vaccination was assessed. Statistical processing of the results was performed using StatPlus Pro 6.2.0.0 software (license number 2883).Results. Сonsecutive vaccination with pneumococcal conjugate and polysaccharide vaccines leads to decreased isolation rate of pneuniococcus from the sputum of CODP patients. The frequency of exacerbations, the need for antibiotic chemotherapy and hospitalizations also goes down.
Female Genital Mutilation/Cutting Education for Midwives and Nurses as Informed by Women’s Experiences: Protocol for an Exploratory Sequential Mixed Methods Study
Authors: Diaz Monica Pilar , Steen Mary , Brown Angela , Fleet Julie-Anne , Williams Jan 
Published: August 2021

Background
Female genital mutilation/cutting (FGM/C) is a complex and deeply rooted sociocultural custom that is innately entrenched in the lives of those who continue its practice despite the physical and psychological dangers it perpetrates. FGM/C is considered a significant independent risk factor for adverse maternal and fetal outcomes in pregnancy and childbirth. Several studies in high-income countries have explored the experiences and needs of women with FGM/C as well as the knowledge of the health professionals, particularly midwives and nurses, who care for them. However, to date, no studies have evaluated the implementation of education for health professionals in high-income countries to meet the specific needs of women with FGM/C.

Objective
This study aims to explore the impact of an FGM/C education program for midwives and nurses as informed by the experiences of women with FGM/C accessing maternity, gynecological, and sexual health services in South Australia.

Methods
This study will adopt a three-phase, exploratory sequential mixed methods design. Phase 1 will involve the exploration of women with FGM/C views and experiences accessing maternity and gynecological (including sexual health) services in South Australia. The findings from phase 1 will inform phase 2: the development of an educational program for midwives and nurses on the health and cultural needs of women with FGM/C. Phase 3 will involve the evaluation of the program by measuring midwives’ and nurses’ changes in knowledge, attitude, and practice immediately before and after the education as well as 4 months after completing the program. Phase 1 of this study has been approved by the Women’s and Children’s Health Network human research ethics committee (ID number 2021/HRE00156) and the University of South Australia human research ethics committee (ID number 204096).

Results
Phase 1 will commence in August 2021, with the interpretation of findings being undertaken by November 2021. Phase 2 will be developed and facilitated by February 2022, and the final phase of this study will begin in March 2022. This study is expected to be completed by February 2023.

Conclusions
The findings of this research will provide insight into the development and evaluation of education programs for midwives and nurses that includes collaboration with women from culturally and linguistically diverse backgrounds to address the specific cultural and health needs of communities.

International Registered Report Identifier (IRRID)
PRR1-10.2196/32911
PERSEPSI WISATAWAN TERHADAP EKSISTENSI KAWASAN WISATA ALAM PANTAI PANDAWA DESA KUTUH BADUNG BALI
Authors: Swabawa A. Agung Putu , Meirejeki I Nyoman , Setena Made 
Published: August 2021

Penelitian ini dilakukan di kawasan wisata pantai Pandawa desa Kutuh, kecamatan Kuta Selatan, Badung. Tujuan penelitian ini adalah Mendiskripsikan potensi-potensi dan daya tarik wisata yang ada di pantai Pandawa dan untuk mengetahui persepsi wisatawan terhadap produk wisata yang terdapat pantai Pandawa yang nantinya bisa digunakan sebagai bahan pertimbangan dalam melakukan perbaikan pengelolaan Kawasan pantai Pandawa. Pengumpulan data yang dilakukan dengan menggunakan metode metode servey, kuesioner, melakukan wawancara baik dengan pengelola maupun dengan wisatawan. Data dianalisis dengan teknik analisis kuantitatif, yaitu teknik analisis untuk menganalisa data kuantitatif dengan menggunakan statistik deskriptif yang digunakan untuk mengukur sifat, pendapat dan persepsi seseorang. Dari hasil analisis menunjukkan Potensi dan daya tarik yang terdapat di Pantai Pandawa yang bisa dikembangkan menjadi kawasan wisata atau produk wisata, meliputi: tebing kapur yang menjulang tinggi, pantai berpasir putih, rumput laut, laut biru yang jernih, taman terumbu karang (coral garden). Produk wisata kreatif yang bisa dikembangkan dengan melihat potensi yang ada di pantai Pandawa adalah museum bahari dan wisata budi daya dan kuliner rumput. Persepsi wisatawaan terhadap kondisi alam pantai Pandawa secara keseluruhan dalam katagori baik, namun masih ada persepsi wisatawan asing dalam katagori cukup terhadap prasarana umum yang perlu mendapatkan perhatian manajemen pantai Pandawa. Maka dalam rangka meningkatkan popularitas kawasan pantai Pandawa, perlu melakukan beberapa hal sebagai berikut: menata lingkungan alam yang ada di pantai Pandawa, perlu melestarikan adat istiadat yang ada dan meningkatkan kreasi seni budaya, meningkatkan kapasitas, jumlah dan kualitas prasarana umum, meningkatkan jumlah dan kualitas sarana paraiwisata, dan merperbaiki manajemen lingkungan dan manajemen operasional pantai Pandawa yang berbasis profesionalisme
Analysis and evaluation of urban socioeconomic dimensions
Authors: Eilaf Mourad Alashkar , Alekseev Yuri V. , Majorzadehzahiri Alireza 
Published: August 2021

Introduction. Following any war, the destruction of cities causes severe damage to the lives of citizens, so urban planning and accelerating the process of renovation and development of a city is the priority of every country after the war, in order to reduce the damage caused by war. Since then, citizens can resume their normal living in their hometowns. The process of urban renovation and development takes a long time, and the main urban indicators should be regularly evaluated in different dimensions to find out whether the living environment has improved and the preset urban goals have been achieved.
Materials and methods. In this study, the process of renovation and development of the city of Homs was analyzed by evaluating the pre-selected social and economic indicators. The sign test and the Wilcoxon test were used to evaluate and compare the indicators before and after the war.
Results. The results of the research show that the null hypothesis of this research was rejected with a z-value of –3.137916 and a p-value of 0.002 in respect of the social dimension. Also, the zero hypothesis of this research is rejected in the economic dimension according to the results of the Wilcoxon test. The results show that the z-value is equal to –2.075 and the p-value is equal to 0.038, which is less than 0.50 and, hence, insignificant. The rejection of the null hypothesis and the large number of negative indicators in the social dimension indicate that the process of renovation and development of the city of Homs is very slow after the war and the city has not been able to approach the desired stable condition.
Conclusions. This research has found that only 11 indicators out of 45 improved in the process of renovation and development of the city of Homs after the war if compared to the pre-war period. In fact, more than 75 % of selected indicators were negative, and this shows the slow pace of urban renovation and development with an emphasis on the sustainable city of Homs.
The Urgency of Institutional Development of Cassava Industry in Daerah Istimewa Yogyakarta and Jawa Tengah
Authors: Maulida Yuhan Farah , Subejo  , Hardyastuti Suhatmini 
Published: August 2021

The study shows that there was variation in the process of cassava-based food production. In Daerah Istimewa Yogyakarta (DIY) and Central Java, the farming systems were still subsistence oriented as the members still carried out traditional farming and worked without practicing intensive farming. However, the cassava-based food processing had already been commercially oriented. Some farmers have successfully collaborated with the larger cassava industry who were profit and commercially oriented. Some agribusiness units required specific varieties, but others opened to any varieties of cassava. The various arrangements have created different patterns of partnership. There were three types of business partnerships namely (1) growers and small-scale manufacturers; (2) partnership among growers, raw material processors, food manufacturers, and distributors or sellers; and (3) partnership among growers, small or large manufacturers and distributors or sellers. Among those three patterns, some enterprises had already performed a business-oriented processing method and quality assurance which requires best quality of raw cassava. This is resulted in a better selling price. Business partnerships can guarantee the sustainability of business relationships among business units. A better upstream-downstream relation needs to be developed to prevent the risks of raw materials supply.
The Impact of a Structured Electronic Interacting Brainstorming Platform
Authors: Chen Wei , Trotman Ken T. , Zhang Xiaoyue (Jessica) 
Published: August 2021

SUMMARY
With the advancements in technology and the recent trends in how audit teams communicate, audit firms increasingly develop and rely on computer-mediated communications and online platforms in the conduct of audits. We examine the effects of two different electronic interacting brainstorming platforms, structured (idea inputs organized into trees and shown by categories/topics) and non-structured (idea inputs in chronological sequence), on audit team brainstorming performance. While the psychology literature suggests potential benefits from the structured brainstorming platforms, we find that, in a fraud hypothesis generation task, a structured brainstorming platform does not improve audit team fraud brainstorming performance (either quantity or quality of fraud hypotheses generated). Further, we find that a structured brainstorming platform reduces the differences in brainstorming performance and mental simulations between managers and seniors. This is because a structured brainstorming platform reduces managers' performance, although it has no negative effects on seniors' performance.
Data Availability: Contact the authors.