bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Perioperative Outcomes Between Precise and Routine Segmentectomy for Patients With Early-Stage Lung Cancer Presenting as Ground-Glass Opacities: A Propensity Score-Matched Study
Authors: Wu Xianning , Li Tian , Zhang Chuankai , Wu Gao , Xiong Ran , Xu Meiqing , Su Dan , Xie Mingran 
Published: April 2021

IntroductionSegmentectomy is widely used for early-stage lung cancer presenting as single or multiple ground-glass opacities (GGOs). Precise segmentectomy is the recommended procedure in China. However, clinically, most routine segmentectomies are performed using only high-resolution computed tomography (CT). The aim of this study was to evaluate the effect of two segmentectomy approaches for GGOs in the lung.MethodsFrom January 2020 to September 2020, 55 precise segmentectomies performed with real-time guidance using 3D reconstruction and 343 routine segmentectomies for patients with single or multiple GGOs were performed as uniportal procedures. To reduce bias related to outcomes, preoperative clinical factors were used for propensity score matching (1:1); 55 precision and 55 routine segmentectomies were selected and further analyzed. Perioperative outcomes, namely operation time, blood loss, resection margins, number of removed lymph nodes, postoperative pulmonary function (1 month after surgery), length of postoperative stay, and postoperative complications were compared between the two groups.ResultsPatients constituted 43 men and 67 women, with an age range of 25–68 years (median: 53 years). No significant differences were seen between the groups regarding blood loss, complications, histological type, and postoperative pulmonary function, and there were no 30-day postoperative deaths in either group. The median operation time for the Precision group (74 min) was longer than in the Routine group (55 min) (p &lt;0.01), and the number of removed lymph nodes in the Precision group (5 ± 1.1) was higher than in the Routine group (3 ± 0.8) (p &lt;0.01). Chest tube duration days and postoperative stay days were similar in both groups; however, the rate of air leakage on postoperative day 1 was higher in the Precision group (p = 0.020). All patients in the Precision group had adequate resection margins. Four patients (7.3%) undergoing complex segmentectomy in the Routine group had inadequate resection margins and required resection of additional lung tissue.ConclusionRoutine segmentectomy can significantly shorten the operation time and might prevent postoperative air leakage in uniportal segmentectomy for lung GGOs. However, precision segmentectomy may be more precise for complex cases, ensuring adequate resection margins and lymph node dissection.
Shexiang Baoxin Pill, a Proprietary Multi-Constituent Chinese Medicine, Prevents Locomotor and Cognitive Impairment Caused by Brain Ischemia and Reperfusion Injury in Rats: A Potential Therapy for Neuropsychiatric Sequelae of Stroke
Authors: Qin Zong-Shi , Zheng Yu , Zhou Xi-Dan , Shi Dong-Dong , Cheng Dan , Shek Chun Shum , Zhan Chang-Sen , Zhang Zhang-Jin 
Published: April 2021

Ischemic stroke is a common type of cerebrovascular event and also the leading cause of disability. Post-stroke cognitive impairment occurs frequently in stroke survivors. Shexiang Baoxin Pill (SBP) is a proprietary Chinese medicine, initially used to treat cardiovascular diseases. Herein, we aim to explore the effects of SBP on oxygen glucose deprivation and reoxygenation (OGD/R) in neuronal cells (CATH.a) and cerebral ischemia/reperfusion injury induced post-stroke cognitive impairment in middle cerebral artery occlusion (MCAO) rat model. MCAO rats received two doses of oral SBP treatment (28 or 56 mg/kg) after 1 h of operation and once daily for 2 weeks continuously. Behavioral tests, immunoblotting, and immunofluorescence were examined after 14 days. Current data suggest that SBP enhanced cell viability and downregulated apoptosis via activating the PI3K/Akt signaling pathway in CATH. a cells. Furthermore, 14 days of SBP treatment promoted the recovery of learning and locomotor function in the MCAO rats. SBP up-regulated the expression of p-Akt, p-GSK3β, as well as the expression of NMDAR1, PSD-95, and AMPAR. Also, SBP down-regulated the expression of p-CaMKII. These results indicated that long-term SBP treatment might be a potential option for cognitive impairment induced by the ischemic stroke.
Minoxidil-Coated Lysozyme-Shelled Microbubbes Combined With Ultrasound for the Enhancement of Hair Follicle Growth: Efficacy In Vitro and In Vivo
Authors: Liao Ai-Ho , Huang Yu-Jhen , Chuang Ho-Chiao , Wang Chih-Hung , Shih Cheng-Ping , Chiang Chien-Ping 
Published: April 2021

Lysozyme (Lyz) is an antimicrobial peptide, a safe adjunct, and it has been indicated that Lyz can promote vibrissae follicle growth by enhancing the hair-inductive capacity of dermal papilla cells in mice. The present study produced a new type of minoxidil (Mx)-coated antifungal Lyz-shelled microbubble (LyzMB) for inhibiting bacteria and allergies on the oily scalp. The potential of Mx-coated LyzMBs (Mx-LyzMBs) combined with ultrasound (US) and the role of LyzMB fragments in enhancing hair follicle growth were investigated. Mx grafted with LyzMBs were synthesized and the loading efficiency of Mx on cationic LyzMBs was 20.3%. The biological activity of Lyz in skin was determined using an activity assay kit and immunohistochemistry expression, and the activities in the US+Mx-LyzMBs group were 65.8 and 118.5 μU/mL at 6 and 18 h, respectively. In hair follicle cell culture experiments, the lengths of hair follicle cells were significantly enhanced in the US+Mx-LyzMBs group (108.2 ± 11.6 μm) compared to in the US+LyzMBs+Mx group (44.3 ± 9.8 μm) and the group with Mx alone (79.6 ± 12.0 μm) on day 2 (p &lt; 0.001). During 21 days of treatment in animal experiments, the growth rates at days 10 and 14 in the US+Mx-LyzMBs group increased by 19.4 and 65.7%, respectively, and there were significant differences (p &lt; 0.05) between the US+Mx-LyzMBs group and the other four groups. These findings indicate that 1-MHz US (applied at 3 W/cm2, acoustic pressure = 0.266 MPa) for 1 min combined with Mx-LyzMBs can significantly increase more penetration of Mx and LyzMB fragments into skin and enhance hair growth than Mx alone.
The Effects of TIME-IN on Emotion Regulation, Externalizing, and Internalizing Problems in Promoting School Readiness
Authors: Weymeis Henk , Van Leeuwen Karla , Braet Caroline 
Published: April 2021

Children’s readiness for school is often threatened by the occurrence of both externalizing and internalizing problems. Previous research has shown that Positive Behavioral Interventions and Supports (PBIS) is particularly effective for fostering children’s behavioral skills and reducing externalizing problems. However, whether PBIS can enhance children’s emotional skills and reduce internalizing problems is less clear. Therefore, TIME-IN was developed, which extends PBIS by also including emotional support systems. It was tested whether TIME-IN was effective for (a) improving emotion regulation and (b) reducing depressive symptoms. Furthermore, it was tentatively explored whether TIME-IN is accompanied by more than natural fluctuations in both children’s externalizing and internalizing problems. The effectiveness of TIME-IN was evaluated in a non-randomized study, in which an intervention group was compared with a matched control group. Both research questions were addressed in a sample consisting of 81 children between 8 and 12 years of age with special educational needs. Questionnaires for teachers (i.e., TRF), children (i.e., FEEL-KJ and CDI), and their parents (i.e., CBCL) were administered at the beginning (T0) and the end of the school year (T1) using multi-informant assessment. Only indicative evidence was found for the hypothesis that TIME-IN improved children’s emotion regulation. Practical implications, strengths, and limitations were discussed.Clinical Trial Registration:This work was retrospectively registered at International Standard Registered Clinical/soCial sTudy Number (ISRCTN) registry ISRCTN54456609 (Weymeis, 2017). Registered 28 March 2017.
Changes in Vitamin A Levels and the Effect of Early Vitamin A Supplementation on Vitamin A Levels in Infants Throughout the First 6 Months of Life: A Prospective Cohort Study in Chongqing, China
Authors: Liu Huan , Chen Qixiong , Yu Linchao , Yang Ting , Chen Jie , Miao Jingkun , Li Tingyu 
Published: April 2021

Objectives: This study aimed to explore the changes in infant vitamin A (VA) status and the effect of early VA supplementation on VA level throughout the first 6 months of life.Methods: A prospective cohort study was conducted in Chongqing, China. A total of 1,016 healthy infants were enrolled at birth. Then, 930, 882, 854 and 822 healthy infants were followed up at postnatal day 7 and postnatal months 1, 3, and 6, respectively. Blood samples and dietary survey and physical development data were collected. Serum VA was measured by chromatography tandem-mass spectrometry and was classified according to the VA deficiency (VAD) criteria for older children aged 6–70 months (&lt;0.70, 0.70–1.05, ≥1.05 μmol/L). Normally distributed continuous variables are presented as the mean ± standard deviation. The categorical variables are described by the frequency and percentage (%). The reference interval for the VA level was the 2.5th−97.5th percentile. Changes in VA status with age and the relationship of VA supplementation with VA level were investigated by generalized estimating equations followed by Bonferroni post hoc test, controlling for the effects of feeding pattern and sex.Results: Infant VA levels increased significantly from 0.499 ± 0.146 to 1.061 ± 0.414 μmol/L with age at 6 months, even without VA supplementation (P &lt; 0.05). From birth to 6 months, the percentage of infants with a VA level &lt;0.70 μmol/L decreased from 88.6 to 19.5%. During follow-up, no infant demonstrated clinical VAD conditions, such as night blindness, conjunctival xerosis or Bitot's spots. Less than 7.0% of infants were underdeveloped in terms of weight, length and head circumference. The VA status of infants with VA≥0.588 μmol/L at birth gradually increased to adequate VA (VA ≥ 1.05 μmol/L) at 6 months. For these infants, there was no significant difference in VA level between the VA supplementation and non-supplementation groups (P &gt; 0.05). Infants with VA &lt;0.430 μmol/L at birth still had VA &lt;0.70 μmol/L at 6 months; in this group, VA levels increased by 0.08 μmol/L more among supplemented infants than among non-supplemented infants (P &lt; 0.05).Conclusions: A low VA level among neonates at birth may be a normal physiological state and may increase with age; thus, not all neonates may need early VA supplementation. More multicenter studies are needed to determine a new cutoff point for the diagnosis of neonatal VAD and the administration of nutritional intervention.
Undergraduates’ Reading Habit: A Study Based on South Eastern University of Sri Lanka
Authors: Abdullah M M A , Farhan M Y M , Mazahir S M M 
Published: April 2021

Reading makes a man perfect and it is very essential component to University students. Hence, students face various obstacles in developing reading habits. Therefore, with the aim of assessing students’ reading habits and identifying the changes and the factors infl uenced when they pursue education through online learning tools due to corona fears, the study was conducted with second year students of Department of Islamic Studies of South Eastern University of Sri Lanka. For this study, which was carried out using quantitative research methods, a fi lled questionnaire was obtained as primary data from 121 of the 174 students studying in the year through Google Forms, analyzed through MS Excel and the results were described. Secondary data such as research articles, journals, and web articles related to the topic were also used. At the end of the study, it was found that students’ reading habit was healthy, the amount of time they spent on daily reading varied, their reading habits have declined due to continuing education through online from home and factors such as lack of library, diffi culty in reading on electronic devices, home works, social media, laziness, workload, sleepiness and increase in data cost have more infl uence on their reading decline, they have the habit of reading from both hard and soft sources, most of them use their smartphones to read the soft copy, while reading through electronic devices they face various problems such as not being able to read for a long time, headache, numbness like reading a book in hand, boredom, inability to read small letters, wasting more time and forgetting easily,. The conclusion of this study was that the continuation of educational activities from home had a negative impact on the reading habits of the students for various reasons. However, the positive change in their reading habits after entering university has been a motivating force for them to continue reading under any circumstances. At the same time, where guidance is provided to overcome challenges, they face in developing reading habits, further positive improvements can be expected in their reading habits.
Análise da presença da atividade da enzima alfa-amilase salivar na espécie bovina
Authors: Oliveira Natan Dias de , Silva Anne Karoline  Mendes da , Bernis Valéria Magro Octaviano , Bernis Filho Walter  Octaviano 
Published: April 2021

A principal enzima salivar responsável pela digestão dos carboidratos é a alfa-amilase. Entretanto, estudos sobre a presença desta enzima em bovinos são escassos e as vezes contraditórios. Diante disso, o objetivo dessa pesquisa foi verificar a presença da atividade da enzima alfa-amilase em bovinos. O método usado para a determinação da enzima foi o colorimétrico modificado, utilizando para tal o kit comercial “Amilase Colorimétrica K003” ( Bioclin, Quibasa Química Básica Ltda, Belo Horizonte, MG, Brasil). A análise foi realizada mediante a visualização macroscópica da coloração após a amostra ser incubada com o substrato amido, e pela adição do iodo; o amido não hidrolisado adquire coloração azul/preta que diminui proporcionalmente à atividade enzimática, sendo comparado com um controle. Observou-se que nenhuma amostra apresentou resultados colorimétricos que apontam a presença da alfa amilase, sendo assim possível sugerir que, não há presença significativa desta proteína na saliva de bovinos que seja capaz de hidrolisar o amido.
Identifikasi Ekologi Sarang Elang Jawa (Nisaetus bartelsi) Di Taman Nasional Gunung Halimun Salak, Resort Gunung Salak I
Authors: Iskandar Ratih Ratna , Elfidasari Dewi , Pairah Pairah 
Published: April 2021

(Article History: Received November 11, 2020; Revised January 5, 2021; Accepted 28 February 2021) ABSTRAKSalah satu burung pemangsa yang terdapat di Indonesia adalah Elang Jawa (Nisaetus bartelsi). Taman Nasional Gunung Halimun Salak (TNGHS) adalah salah satu taman nasional yang ada di Indonesia. TNGHS merupakan salah satu habitat bagi Elang Jawa, hal ini dikarenakan kondisinya yang bisa dikatakan masih cukup baik dan data-data mengenai burung Elang Jawa di Kawasan TNGHS masih belum memadai. Oleh karena itu, diperlukan eksplorasi mengenai habitat populasi Elang Jawa di Kawasan TNGHS. Penelitian ini bertujuan untuk menjelaskan habitat dan sarang Elang Jawa yang meliputi lokasi, jenis pohon dan ciri-ciri pohon yang digunakan sebagai tempat meletakan sarang di TNGHS. Hal ini berguna untuk memberikan informasi tentang habitat sarang Elang Jawa pada Kawasan tersebut. Metode yang digunakan yaitu survei, pemantauan sarang, wawancara, pengumpulan dan analisis data. Berdasarkan hasil pengamatan N. bartelsi, menggunakan pohon Litsea cordata (Huru) dengan ketinggian 40-60 meter sebagai sarangnya, dan pohon Schima wallichii (Puspa) untuk bertengger. Kata Kunci: Elang Jawa; Habitat; Sarang; TNGHS ABSTRACTOne of the birds of prey found in Indonesia is the Javan Hawk Eagle (Nisaetus bartelsi). Mount Halimun Salak National Park (TNGHS) is one of the national parks in Indonesia. TNGHS is one of the habitats for Javanese eagles. This is because the conditions are still quite good and data on Javanese eagles in the TNGHS area are still inadequate. Therefore, it is necessary to explore the habitat of the Javan hawk population in the TNGHS area. This study aims to explain the habitat and nest of Javanese eagles which include location, tree species and tree characteristics used as a place to place nests in TNGHS. This is useful for providing information about the Javan hawk nest habitat in the area. The methods used are surveys, nest monitoring, interviews, data collection and analysis. Based on the observations of N. bartelsi, using the tree Litsea cordata (Huru) with a height of 40-60 meters as a nest, and the tree Schima wallichii (Puspa) for perching.Keywords: Javan hawk eagle; Habitat; Nest; TNGHS
Jenis-Jenis Tumbuhan Suku Zingiberaceae di Cagar Alam Pangi Binangga Sulawesi Tengah
Authors: Ramadanil Ramadanil , Rizaldi Reza , M Saleh M Fajri Ramadan , Ramawangsa Panji 
Published: April 2021

(Article History: Received 14 November 2020; Revised 15 December 2020; Accepted 5 January 2021) ABSTRAKPenelitian tentang keanekaragaman jenis jahe-jahean (Zingiberaceae) di Cagar Alam Pangi Binangga telah dilakukan dari bulan Oktober 2019 - Januari 2020. Penelitian bertujuan untuk mengkaji jenis-jenis tumbuhan yang tergolong Zingiberaceae di Cagar Alam Pangi Binangga. Penelitian dilakukan secara survei di lapangan, menggunakan metoda eksplorasi (jelajah). Identifikasi spesimen dilakukan di Laboratorium Biosistematika Tumbuhan Jurusan Biologi Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Tadulako. Hasil penelitian menunjukan terdapat sebanyak 8 jenis yang terdiri atas 4 marga. Jenis yang ditemukan adalah Alpinia eremoclamis, A. rubricaulis, Alpinia sp1, Alpinia sp2, Etlingera tubilabrum, Etlingera sp., Sulettaria sp. dan Zingiber sp.Kata kunci: Cagar Alam Pangi Binangga; Sulawesi Tengah; Zingiberaceae ABSTRACTResearch on Diversity of ginger (Zingiberaceae) in the Pangi Binangga Nature Reserve has been carried out from October 2019 - January 2020. The research was aimed to determine the species of plants belong to Zingiberaceae family in the Pangi Binangga Nature Reserve. The study was conducted by survey in the field, using exploration methods (exploring). Specimen identification was carried out at the Plant Biosystematics Laboratory, Department of Biology, Faculty of Mathematics and Natural Sciences, Tadulako University. The results showed as many as 8 species consisting of 4 genera. The species found were Alpinia eremoclamis, A. rubricaulis, Alpinia sp1, Alpinia sp2, Etlingera tubilabrum, Etlingera sp., Sulettaria sp. dan Zingiber sp.Keywords: Pangi Binangga Nature Reserve; Central Sulawesi; Zingiberaceae
The Influence of Cutting Age and Liquid Organic Fertilizer Dosage on The Yield of King Grass (Pennisetum purpupoides Schumach) as Source of Livestock
Authors: Berliana Yunida , Sihombing Juli Mutiara , Khairani Khairani , Wahyudi Erfan 
Published: April 2021

Introduction: Grasses is one part of the forage, that it is necessary to support the production of grass management. The research was to determine the effect of cutting age and the use of liquid organic fertilizers (LOF) for king grass in overcoming the problem of forage feed availability.
Materials and Methods: This research was conducted at the experimental field in Faculty of Agriculture and Animal Husbandry, Universitas Tjut Nyak Dhien, Medan Tuntungan Subdistrict, North Sumatra. This research used a split plot design with two factors. The main-plot was the cutting age, include T1= 35 days; T2= 45 days; T3= 55 days. The sub-plot was the different dosage of LOF, such as P0= un-fertilization; P1= 50 l.ha-1; P2= 75 l.ha-1; P3= 100 l.ha-1. The parameters were analyzed the F-test and continued with the LSD at level of 5%.
Results: The cutting age significantly increased the tillers, yield of fresh matter, yield of dry matter, and storage capacity, but it had insignificant effect on the height of king grass with the highest increase was at the age of 55 days. The LOF doses significantly increased the height of king grass, tillers, and yield of fresh matter with the highest increase at the dose of 100 l.ha-1, but it had insignificant effect on yield of dry matter and storage capacity. Interaction between the cutting age with LOF significantly increase the highest of king grass height at 100 l.ha-1 of LOF + 55 days of 220.67 cm.
<b> ¿Qué comemos en la Escuela? Socialización y vida escolar en Guatemala</b><br/><i>What do we eat at school? Socialization and the school life in Guatemala<i>
Authors: Gómez-Guerra Susan I. , Jiménez-Tuy M. Virginia 
Published: April 2021

El proyecto de investigación sobre el cual fue elaborado este artículo, se orientó a analizar cómo los procesos de socialización influyen en la vida escolar y situación nutricional de niñas y niños que asisten a tres escuelas públicas ubicadas en zonas distintas; ya que se identificó que estudios anteriores centraban su atención en la medición cuantitativa del fenómeno de la nutrición y la alimentación. Desde un enfoque sociológico se plantearon varias unidades de análisis como: la vida escolar de la que se determinó la influencia de la tienda escolar, la interacción social entre niñas y niños y el rol educativo de los maestros. Todas esas influencias recibidas modifican la situación nutricional de niñas y niños; para identificar estos cambios en el comportamiento se procedió a la construcción de una guía de observación, una guía de entrevista y de grupo focal. A partir de la aplicación de estas técnicas y del análisis de la información obtenida, se identificó que la educación alimentaria-nutricional en las escuelas visitadas es no planificada, poco frecuente, no incluye a los familiares y se limita a consejos ocasionales pues los escolares entrevistados respondieron que no se les impartían charlas o talleres sobre el tema; aunque en contraste algunos maestros afirmaron darlas, el proceso no es el adecuado por lo anteriormente descrito.
Beneficios socieconómicos de las familias que pertenecen a las concesiones forestales comunitarias en Petén, Guatemala
Authors: Corzo Marquez Amilcar Rolando 
Published: April 2021

Las concesiones forestales comunitarias creadas en la década de los años noventa del siglo pasado, son una estrategia de conservación en la Reserva de la Biósfera Maya. La evidencia de monitoreo sobre la cobertura boscosa indica un impacto positivo en la conservación de los bosques. El estudio analiza el impacto socioeconómico a nivel del hogar en los grupos concesionarios comparándolos con grupos sin concesión. La evidencia indica que,aunque el efecto no es muy grande, los grupos que pertenecen a las concesiones tienen mayores ingresos, mejores condiciones de hogar, acceso a servicios de salud, mayor acceso a educación y percepciones sobre los recursos naturales y su conservación más afines a la teoría conservacionista. Pese a que hay diferencias socioeconómicas a favor de las concesiones, el acceso a esos beneficios es menor en las concesiones que se encuentran dentro de la Reserva, en contraposición a los grupos concesionarios urbanos que viven fuera de ella.