bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of the COVID-19 pandemic in the Portuguese population: Consumption of alcohol, stimulant drinks, illegal substances, and pharmaceuticals
Authors: Fernandes Sara , Sosa-Napolskij Milaydis , Lobo Graça , Silva Isabel 
Published: November 2021

Background
The measures implemented by governments worldwide to control and prevent the spread of the COVID-19 have impacted the populations and directly influenced individuals’ quality of life and consumption habits.

Objective
This work investigates the Portuguese population’s changes in alcohol, stimulants drinks, illegal substances, and pharmaceutical consumptions habits during the COVID-19 pandemic.

Methods
An online questionnaire comprising seven groups of questions–with one group referring to alcohol, stimulant drinks, illegal substances, and pharmaceuticals consumption habits–was made available to the general adult population of mainland Portugal from the 26th January through the 31st of March 2021. After applying the inclusion criteria, 1666 questionnaires were selected and analysed using descriptive and inferential statistics.

Results
Our results show that 48.9% of the participants have alcohol drinking habits and increased their alcohol consumption by 16% after the beginning of the COVID-19 pandemic lockdown. Furthermore, 8.7% of the respondents felt the need to increase their consumption of stimulant drinks, especially coffee, the most consumed stimulant drink (77.9%). We also observed that of the 3.1% of respondents who are usual consumers of illegal substances, 26.9% increased their consumption of these substances during the COVID-19 pandemic. Concerning pharmaceuticals, 23.2% of the respondents expressed their need to take a therapeutic drug after the start of the COVID-19 pandemic. The profile of common consumers of alcohol, stimulant drinks, illegal substances, and pharmaceuticals in the COVID-19 pandemic context is contrasting and varies according to gender, age, and employment status.

Conclusions
The COVID-19 pandemic led to an increase in the consumption of alcohol, stimulant drinks, illegal substances, and pharmaceuticals prescribed to treat anxiety, depression, and sleep changes in the Portuguese population. These new consumption patterns have probably aggravated domestic violence, mental diseases, and impairment of family quality of life in the Portuguese population.
Association Between Peripheral Blood Monocyte Count and Mucosal Healing in Japanese Patients With Ulcerative Colitis
Authors: Furukawa Shinya , Ikeda Yoshio , Yagi Sen , Miyake Teruki , Shiraishi Kana , Tange Kazuhiro , Hashimoto Yu , Mori Kenichirou , Ninomiya Tomoyuki , Suzuki Seiyuu , Shibata Naozumi , Murakami Hidehiro , Ohashi Katsuhisa , Hasebe Aki , Tomida Hideomi , Yamamoto Yasunori , Takeshita Eiji , Hiasa Yoichi 
Published: November 2021

INTRODUCTION:
Monocytes play an important role in innate immunity. Some epidemiological evidence indicates an association between peripheral blood monocytes and ulcerative colitis (UC). The association between peripheral blood monocytes and mucosal healing (MH), however, remains unclear. We evaluated this issue in patients with UC.

METHODS:
Study subjects consisted of 272 Japanese patients with UC. Monocyte counts were taken in the morning after overnight fasting. Monocyte count was divided into tertiles based on the distribution of values among all study subjects. Information on clinical remission was obtained from medical records. MH was assessed using the Mayo endoscopic subscore.

RESULTS:
The mean monocyte count was 360.1 ± 155.3/mm3. Rates of clinical remission, MH, and complete MH were 61.0%, 66.2%, and 27.9%, respectively. High monocyte count was significantly inversely associated with clinical remission, MH, and complete MH (adjusted odds ratio [OR] 0.45 [95% confidence interval [CI]: 0.23–0.89], OR 0.45 [95% CI: 0.23–0.89], and OR 0.48 [95% CI: 0.23–0.97], respectively). Patients were also classified according to C-reactive protein (CRP) levels; in the low CRP group (<0.1 mg/dL), high monocyte count was independently inversely associated with complete MH but not with clinical remission or MH (OR 0.33 [95% CI: 0.10–0.92], P for trend = 0.027). In the high CRP group, there was no association between monocyte count and clinical outcomes.

DISCUSSION:
Our findings suggest that peripheral blood monocyte count can be used as a serum supplemental marker for MH in UC patients with low CRP levels.
The Effect of Participatory Budgeting, Information Asymmetry, and Organizational Commitment on Budgetary Slack
Authors: Sarwendhi Rezza Arlinda 
Published: November 2021

This study aims to analyze budgetary slack at the management level.Â This budgetary slack is viewed from several independent variablesÂ consisting of participatory budgeting, information asymmetry, andÂ organizational commitment by making managers spread across the city of Surabaya as the research samples. Participatory budgeting is budgeting that involves all levels of personnel in preparing the budget. The opportunity for employees to participate in preparing the budget is closely related to the level of budgetary slack. Information asymmetry is the difference in information held between the principal and theÂ agent. Organizational commitment can be interpreted as a situationÂ where the executives stay in an organization where they work and areÂ committed to their work. This study uses a quantitative approachÂ involving multiple linear regression analysis. The results show thatÂ participatory budgeting has no effect on budgetary slack, whileÂ information asymmetry and organizational commitment have an effectÂ on budgetary slack.
Towards temperature controlled retinal laser treatment with a single laser at 10 kHz repetition rate
Authors: Mordmüller Mario , Kleyman Viktoria , Schaller Manuel , Wilson Mitsuru , Theisen-Kunde Dirk , Worthmann Karl , Müller Matthias A. , Brinkmann Ralf 
Published: November 2021

Abstract
Laser photocoagulation is one of the most frequently used treatment approaches in ophthalmology for a variety of retinal diseases. Depending on indication, treatment intensity varies from application of specific micro injuries down to gentle temperature increases without inducing cell damage. Especially for the latter, proper energy dosing is still a challenging issue, which mostly relies on the physician’s experience. Pulsed laser photoacoustic temperature measurement has already proven its ability for automated irradiation control during laser treatment but suffers from a comparatively high instrumental effort due to combination with a conventional continuous wave treatment laser. In this paper, a simplified setup with a single pulsed laser at 10 kHz repetition rate is presented. The setup combines the instrumentation for treatment as well as temperature measurement and control in a single device. In order to compare the solely pulsed heating with continuous wave (cw) tissue heating, pulse energies of 4 µJ were applied with a repetition rate of 1 kHz to probe the temperature rise, respectively. With the same average laser power of 60 mW an almost identical temporal temperature course was retrieved in both irradiation modes as expected. The ability to reach and maintain a chosen aim temperature of 41 °C is demonstrated by means of model predictive control (MPC) and extended Kalman filtering at a the measurement rate of 250 Hz with an accuracy of less than ±0.1 °C. A major advantage of optimization-based control techniques like MPC is their capability of rigorously ensuring constraints, e.g., temperature limits, and thus, realizing a more reliable and secure temperature control during retinal laser irradiation.
Machine Learning for the Relationship of High-Energy Electron Flux between GEO and MEO with Application to Missing Values Imputation for Beidou MEO Data
Authors: Cui Ruifei , Jiang Yu , Tian Chao , Zhang Riwei , Hu Sihui , Li Jiyun 
Published: November 2021

AbstractWe consider the problem of building the relationship of high-energy electron flux between Geostationary Earth Orbit (GEO) and Medium Earth Orbit (MEO). A time-series decomposition technique is first applied to the original data, resulting in trend and detrended part for both GEO and MEO data. Then we predict MEO trend with GEO data using three machine learning models: Linear Regression (LR), Random Forest (RF), and Multi-Layer Perceptron (MLP). Experiment shows that RF gains best performance in all scenarios. Feature extraction analysis demonstrates that the inclusion of lagged features and (possible) ahead features is substantially helpful to the prediction. At last, an application of imputing missing values for MEO data is presented, in which RF model with selected features is used to handle the trend part while a moving block method is for the detrended part.
Preparation and characteristics of sepiolite-waterborne polyurethane composites
Authors: Xu Tong , Xu Hong , Zhong Yi , Zhang Linping , Qian Di , Hu Yelei , Zhu Yuanzhao , Mao Zhiping 
Published: November 2021

Abstract
A kind of organic/inorganic composite material composed of waterborne polyurethane and sepiolite was prepared in this work. Sepiolite was organically modified by three kinds of silane coupling agents, and then compounded with waterborne polyurethane through layer-by-layer method in order to prepare composite materials. X-ray diffraction (XRD) and Fourier transform infrared (FTIR) show the crystal and chemistry structure of sepiolite samples, and confirmed the preparation of organic sepiolite. Scanning electron microscope (SEM) and energy dispersive X-ray spectroscopy (EDS) showed the surface microstructure and elemental content of sepiolite and organic sepiolite, and was consistent with the XRD results. Transmission electron microscope (TEM) examination of waterborne polyurethane composites surfaces showed that sepiolite particles were regularly dispersed in the waterborne polyurethane matrix. Thermal resistance of waterborne polyurethane composites was determined by thermogravimetry analyzer (TG) and derivative thermogravimetry analyzer (DTG), differential scanning calorimetry (DSC), gas chromatography (GC), and mass chromatography (MS). Mechanical behavior was examined by tensile strength tester, showed higher break strength than that of the control waterborne polyurethane. Therefore, organically modified sepiolite was considered to be a kind of wonderful inorganic material that could be used to improve the thermal stability and mechanical property of polymer.
Exposure to toxic occupations and their association with Parkinson’s disease: a systematic review with meta-analysis
Authors: Chambers-Richards Tamara , Su Yingying , Chireh Batholomew , D’Arcy Carl 
Published: November 2021

Abstract

Objectives
Earlier longitudinal reviews on environmental and occupational toxins and Parkinson’s disease (PD) risk have limitations. This study aimed to determine the strength of association between three types of toxic occupational exposures and the occurrence of PD by diagnostic methods.

Methods
A search was conducted of EMBASE, PubMed/Medline, Toxnet, LILACS, and Cochrane Library databases for longitudinal studies that assessed toxic occupational exposure, Parkinsonian, or related disorders, diagnosed by International Classification of Diseases (ICD) codes, medical records, or confirmation by a neurologist/nurse, and published in the English language from January 1990 to July 2021. Pooled risk ratios (RR) estimates were produced using random-effects models. Systematic review with meta-analysis synthesized the results. Study quality, heterogeneity, and publication bias were examined. High-quality articles that met the inclusion criteria were analyzed.

Results
Twenty-four articles were used in the analyses. The pooled RR for electromagnetic exposure and PD were (RR=1.03, 95% confidence interval [CI] 0.91–1.16) while the pooled RR between PD and metal and pesticide exposure were (RR=1.07, 95% CI 0.92–1.24) and (RR=1.41, 95% CI 1.20–1.65), respectively. Pooled RR for methods of diagnosis and their associations with PD were: confirmation by a neurologist or nurse (RR=2.17, 95% CI 1.32–3.54); ICD codes (RR=1.14, 95% CI 1.03–1.26), and medical records (RR=1.06, 95% CI 0.92–1.21).

Conclusions
Our systematic review provides robust evidence that toxic occupational exposures are significant risk factors for PD especially those diagnosed by neurologists or nurses using standardized methods.
Rapid Analysis of Visual Receptive Fields by Iterative Tomography
Authors: Eiber Calvin D. , Huang Jin Y. , Chen Spencer C. , Zeater Natalie , Pietersen Alexander N. J. , Protti Dario A. , Martin Paul R. 
Published: November 2021

AbstractMany receptive fields in the early visual system show standard (center-surround) structure and can be analyzed using simple drifting patterns and a difference-of-Gaussians (DoG) model, which treats the receptive field as a linear filter of the visual image. But many other receptive fields show nonlinear properties such as selectivity for direction of movement. Such receptive fields are typically studied using discrete stimuli (moving or flashed bars and edges) and are modelled according to the features of the visual image to which they are most sensitive. Here, we harness recent advances in tomographic image analysis to characterize rapidly and simultaneously both the linear and nonlinear components of visual receptive fields. Spiking and intracellular voltage potential responses to briefly flashed bars are analyzed using non-negative matrix factorization (NNMF) and iterative reconstruction tomography (IRT). The method yields high-resolution receptive field maps of individual neurons and neuron ensembles in primate (marmoset, both sexes) lateral geniculate and rodent (mouse, male) retina. We show that the first two IRT components correspond to DoG-equivalent center and surround of standard [magnocellular (M) and parvocellular (P)] receptive fields in primate geniculate. The first two IRT components also reveal the spatiotemporal receptive field structure of nonstandard (on/off-rectifying) receptive fields. In rodent retina we combine NNMF-IRT with patch-clamp recording and dye injection to directly map spatial receptive fields to the underlying anatomy of retinal output neurons. We conclude that NNMF-IRT provides a rapid and flexible framework for study of receptive fields in the early visual system.
Libellus Auguriorum: asztrológiai táblázatok
Authors: Zsoldos Endre 
Published: November 2021

Az OSZK Kézirattárában található a Libellus Auguriorum (Oct. Lat. 761) című 17–18. századi kézirat. Lőcsén készült, a szerző személye ismeretlen. Mint a címe is állítja, a kézirat jóslatokat tartalmaz (1. ábra).1
A szöveg 36 lapot foglal el (1–36r). A 2r–3r oldalakon (2. ábra) ’Primus’ címszó alatt 42 úgynevezett ’váratlan esemény’ van felsorolva, melyek bekövetkezése esetére vonatkoznak a jóslatok. Ezek a Hold égi pozíciójától függenek, az égitestnek a zodiákusban elfoglalt helyzete mutatja meg, hogy az adott esemény bekövetkezte esetén mi várható. Mivel mind a tizenkét állatövi csillagképhez tartozik 42 jóslat, így összesen 504-et tartalmaz belőlük a kézirat.
Features and relationships of metabolic syndrome components in men with androgen deficiency. Part 2. Disorders of carbohydrate and purine metabolism. Retrospective study data
Authors: Pavlova Z. Sh. , Grevina V. Yu. 
Published: November 2021

Introduction. Currently, few epidemiological data on a relation between impaired purine and carbohydrate metabolism and testosterone deficiency in overweight men due to adipose tissue and metabolic syndrome (MS) are available.Aim: to study relationships between disturbances in carbohydrate and purine metabolism and testosterone level in men with adipose tissue excess and MS.Materials and Methods. There were enrolled 64 overweight men to the study. The patients were divided into 3 groups based on the body mass index (BMI): group 1 – with overweight (n = 24), group 2 – with the first degree of obesity (n = 21), group 3 – with the second and third degree of obesity (n = 19). A correlation analysis was carried out between the data on carbohydrate and purine metabolism related to testosterone level and body composition, as well as additionally assessing the level of inter-group difference.Results. A relationship between the parameters of carbohydrate and purine metabolism and the level of total testosterone has been established along with overdeveloped adipose tissue. A weak negative correlation was found across the sample between testosterone and glucose, insulin, and the НОМА-IR (Homeostasis Model Assessment of Insulin Resistance) index. i.e., the higher the glucose level, the higher НОМА-IR index, and the lower the testosterone level. In addition, it was found that along with increasing BMI it was paralleled with higher insulin level. The number of patients with fasting blood glucose levels above 5.6 mmol/L and insulin resistance also increased. In the group with I degree of obesity, a negative correlation was found between the levels of total testosterone and uric acid.Conclusion. Thus, the thesis is confirmed that the more significant the violation of carbohydrate and purine metabolism, the more profound could be androgenic deficiency. Thus, it is obvious that normalization of body composition and removal of excessive adipose tissue would provide a more effective solution in choosing a strategy to treat androgen deficiency and disorders of carbohydrate and purine metabolism in overweight men.
Effect of complications on survival after lung cancer surgery
Authors: YAKŞİ Osman , KILIÇGÜN Ali , ERSEN Ezel , SARBAY İsmail , ÜNAL Mehmet , TURNA Akif , KAYNAK Kamil 
Published: November 2021

Purpose: This study aims to investigate the effect of complications on survival after lung cancer surgery.
Materials and Methods: This is a retrospective study of 802 patients who underwent surgical operations for lung cancer at two centers between January 2002 and December 2019. All patients were retrospectively evaluated according to age, gender, cancer stage, surgical technique, biochemical tests, pulmonary function tests, pulmonary risk index, length of the hospital stay, and the existing number of complications.
Results: In total, 802 patients (%84 males, %16 females) with a mean age of 60 years (range 19-88 years) were included in the study. 5-year overall survival rate was 62.3%. 224 complications occurred in 180 patients (22.4%). The ten most common complications, respectively, were prolonged air leak (54), pneumonia (22), arrhythmia (19), respiratory failure (15), hemorrhage (17), atelectasis (10), pneumothorax-expansion defect (7), arrest (7) bronchopleural fistula (7), subileus-ileus (6). Cancer stage, the existing number of complications, advancing age, and tumor size are parameters that significantly affect survival. The occurs of one or more complications significantly adversely affects survival.
Conclusion: Although the morbidity and mortality of lung cancer surgery have decreased in recent years, it is still high. Advanced stage lung cancer, advancing age, enlargement of tumor size and occurs of complications that negatively affect survival. Careful preoperative preparation may play a role in increasing long-term survival, as well as preventing complications, and decreasing early mortality.
Organizational Factors in Implementation of Patient Safety Culture in Hospitals: Systematic Literature Review
Authors: Darma Septin Srimentari Lely , Purwaningsih Purwaningsih , Ulfiana Elida 
Published: November 2021

Introduction: Patient safety culture is a program organized to minimize the risk of unexpected events and improve patient safety. This study is aimed to explain the relationship between organizational factors in the implementation of patient safety culture in hospitals based on empirical studies in the last five years.Method: ProQuest, ScienceDirect, Sage, CINAHL, and google scholar databases have been searched using indexed keywords in the Medical Subject Heading (MeSH) on 2015-2020. JBI's review with a cross-sectional study design used to assess research quality. The PRISMA flowchart was used to summarize the study selection process in the literature review with inclusion and exclusion criteria adjusted to the PICOS framework.Results: We found 13 journals that consist of three studies discuss about leadership, seven journals describe about resources, and three journals relate to organizational structure. Every country has a different characteristic in implementation of patient safety culture. The thirteen journals came from countries that divided in to three continents, there are Asia, Europe, and Africa. The results of this studyshow that leadership, resources, and, organizational structure can optimize the application of patient safety culture. Leadership support motivates health workers in the room in implementing a patient safety culture. Adequate resources reduce the risk of accidents at work, and an effective organizational structure creates good and conducive performance.Conclusions: Provide between three and five key words in alphabetical order, which accurately identify the paper’s subject, purpose, method and focus. Don't use words or terms in the title as keywords. These keywords will be used for indexing purposes. Keywords cannot be more than 5 words or phrases in alphabetical order
THE RELATIONSHIP OF PARTNER SUPPORT WITH VARIOUS ACTIVITIES OF THE ELDERLY HYPERTENSION
Authors: Angelina Farah Dwita , Haryanto Joni , Ulfiana Elida 
Published: November 2021

Hypertension is a health problem that many elderly suffer from. Blood pressure in the elderly with hypertension can be controlled in various ways, namely doing physical activity regularly, performing activities related to cognitive function, and controlling stress levels so as not to affect contractions or pulsations of the heart and nervous system that can cause blood pressure to increase. The purpose of this study was to determine the relationship of partner support with physical, mental, and social activities of the elderly with hypertension.This study used a correlational non-experimental design with a cross-sectional approach. The number of samples were 102 respondents in the Morokrembangan area, where the sampling used Nonprobability Sampling method, namely Purposive Sampling. The research instrument used partner support questionnaires, Global Physical Activity Questionnaire (GPAQ), mental health practices, social activities and demographic characteristics. The analysis used Spearman Rho test.The results of this study were there was a relationship between partner support with physical activity (p = 0.000; r = 0.589 ), mental activity (p = 0.000; r = 0.778 ), and social activity (p = 0.000; r = 0.671) with positive and unidirectional correlation.As you get older, daily activities will decrease too. The better the support provided by the partner, the higher the level of daily activities carried out by the elderly. Therefore, elderly couples are expected to provide mutual support in carrying out physical, mental, and social activities.