bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on the height of primary school students in Zhuzhou and analysis of influencing factors of short stature
Authors: Ye Xiao-min , Tang Qiong , Yang Yi-can , Wen Xiang-Lan 
Published: February 2025

ObjectiveTo construct a growth curve for children aged 6–12 years residing in Zhuzhou, assess the height distribution among local elementary school students, and analyze the factors contributing to short stature.MethodsWe measured the heights of children from 110 elementary schools in Zhuzhou using cluster sampling. A total of 106,864 samples of children aged 6–12 years were collected and divided into 25 age groups, each spanning three months. The Lambda-Mu-Sigma (LMS) method was employed to calculate the 3rd, 10th, 25th, 50th, 75th, 90th, and 97th percentiles of height for each age group. Children below the 3rd percentile according to the national growth curve made in 2005 were considered to be short stature. The heights of boys and girls in Zhuzhou were compared with the national average heights from 2005. The height growth curve was constructed using the curve estimation function of SPSS software and the influencing factors for the prevalence of short stature were identified using logistic regression analysis based on data obtained from parental questionnaires.ResultsThe prevalence of short stature among children aged 6–12 years in Zhuzhou was found to be 3.97%. Boys exhibited a significantly higher incidence of short stature at 4.53% compared to girls at 3.37%. Children residing in suburban areas showed a notably higher prevalence of short stature (5.80%) compared to their urban counterparts (3.67%), with these disparities proving statistically significant. Logistic regression analysis identified several contributing factors for short stature in this population, including low birth weight, inadequate daily physical activity (less than 0.5 h), father's educational qualification of junior college level or below, short stature of parents, insufficient sleep duration, and male gender.ConclusionTo improve children's height in Zhuzhou, it's important for them to exercise for over 30 min daily and sleep for more than 10 h each night. Regular monitoring of growth and nutrition is crucial. Health education for families with less educated fathers and early intervention for children with short-statured parents are also key strategies.
Pharmacovigilance analysis of polatuzumab plus bendamustine and rituximab treatment protocol: identifying comprehensive safety signals using FDA database
Authors: Wu Fang , Wang Siliang , Xu Xihui , Zhang Weihui , Zhou Jie , Niu Runyan , Cai Wenting , Yang Yonggong , Liu Mengying , Zhang Jinping 
Published: February 2025

BackgroundThe combination of polatuzumab, bendamustine and rituximab (pola+BR) was authorized for the treatment of relapsed or refractory Diffuse large B cell lymphoma (DLBCL). This study used the FDA database to identify safety signals related to the treatment protocol.MethodsThe adverse events (AEs) from 2019Q1 to 2023Q3 were analyzed by calculating the reporting odds ratio. Severe and non-severe cases were compared using either an independent samples t-test or chi-squared (χ2) test. Additionally, a score sheet was employed to prioritize the signals.ResultsIn all database, 58 significant signals were detected within 1,597 patients accepting the treatment protocol. Common AEs like neutropenia, thrombocytopenia, and peripheral neuropathy, as well as other AEs like anaemia, sepsis, cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome (ICANS) were a major focus. In addtion, 51.7%, 45.6% and 1.7% were sorted into low, moderate and high priority in term of clinical importance, respectively. Unexpected significant signals included intestinal obstruction, epilepsy, deep vein thrombosis, haemorrhage, increased blood lactate dehydrogenase and hypercalcemia.ConclusionOur study identified significant AE signals for pola+BR through realworld disproportionality analysis data and analyzed the severity and clinical priority of these signals, which can assist clinicians in managing related AEs.
Socio-demographic factors associated with mental health disorders among rural women in Mymensingh, Bangladesh
Authors: Khan Rizwana , Akter Fahmida , Rahman Musarrat , Amin Nuhu , Rahman Mahbubur , Winch Peter J. 
Published: February 2025

IntroductionIn Bangladesh, the reported prevalence of mental disorders among adults varies from 6.5% to 31.0%. This study aims to identify the socio-demographic factors associated with mental health disorders among rural women in Bangladesh.MethodWe enrolled 401 adult women from four sub-districts of Mymensingh district, Bangladesh. To determine the factors involved, we employed a modified version of the mental state examination (MSE) scale, in addition to questionnaires focusing on socio-demographic information, health, and well-being.ResultThe prevalence of mental health problems, measured by the MSE scale, was 26%. Even after controlling for potential confounders such as respondent's age, education level, spouse's schooling, household income, health status, domestic violence, family disharmony, social security, and support, household income remained significantly associated with behavioral problems. Individuals with higher incomes experience a lower prevalence of mental health disorders (Prevalence Ratio [PR] = 0.48; 95% CI 0.27-0.86). Poor physical health significantly correlated with behavior and mood (PR = 0.77; 95% CI 0.61-0.98). Older respondents encountered more challenges related to memory (PR = 1.42; 95% CI 1.13-1.79).DiscussionThese findings highlight the crucial role of addressing socio-demographic factors, like income and physical health, when promoting mental health among rural women in Bangladesh. By acknowledging and targeting these factors, interventions can be more tailored and effective, ensuring improved well-being and resilience within this population.
Utilizing metagenomic profiling and machine learning model to identify bacterial biomarkers for major depressive disorder
Authors: Wang Xuan , Cao Di , Zhang Hanlin , Chen Wei , Sun Jiaxin , Hu Huimin 
Published: February 2025

BackgroundMajor depressive disorder (MDD) is highly heterogeneous, which provides a significant challenge in the management of this disorder. However, the pathogenesis of major depressive disorder is not fully understood. Studies have shown that depression is highly correlated with gut flora. The objective of this study was to explore the potential of microbial biomarkers in the diagnosis of major depressive disorder.MethodsIn this study, we used a metagenomic approach to analyze the composition and differences of gut bacterial communities in 36 patients with major depressive disorder and 36 healthy individuals. We then applied a Support Vector Machine Recursive Feature Elimination (SVM-RFE) machine learning model to find potential microbial markers.ResultsOur results showed that the alpha diversity of the intestinal flora did not differ significantly in major depressive disorder compared to healthy populations. However, the beta diversity was significantly altered. Machine learning identified 8 MDD-specific bacterial biomarkers, with Alistipes, Dysosmobacter, Actinomyces, Ruthenibacterium, and Thomasclavelia being significantly enriched, while Faecalibacterium, Pseudobutyrivibrio, and Roseburia were significantly reduced, demonstrating superior diagnostic accuracy (area under the curve, AUC = 0.919). In addition, the gut bacteria performed satisfactorily in the validation cohort with an AUC of 0.800 (95% CI: 0.6334-0.9143).ConclusionThis study reveals the complex relationship between gut microbiota and major depressive disorder and provides a scientific basis for the development of a microbiota-based diagnostic tool for depression.
Exploring gendered racism and the mental health of rural Black women
Authors: Ezemenaka Christina J. , Burton Wanda Martin , Newman Sharlene 
Published: February 2025

BackgroundGendered racial microaggressions adversely impact Black college women’s mental health, but less is known about rural Black women’s mental health.ObjectiveExamine the association between gendered racism, depression, and psychological distress.MethodsThis cross-sectional study included 200 rural Black women from the Southeastern United States. Gendered racism was assessed using the Gendered Racial Microaggressions scale (GRMS). Linear regression was used to assess GRM subscales, depression (PHQ-9) and psychological distress (K6) as outcomes.ResultsOf the 200, 21.5% reported depression and 31% reported moderate psychological distress. Depression increased with increasing stress appraisal of gendered racism, p = 0.002.ConclusionGendered racial microaggressions impact the mental health of rural Black women.
Public perceptions and influencing factors of seasonal influenza vaccine uptake in Makkah region, Saudi Arabia: a cross-sectional study
Authors: Alharthi Mohammed S. , Alshehri Abdullah A. , Baali Fahad H. , Altuwairqi Nawaf Awd , Altalhi Meshari Hassan , Almalki Rayan Azib , Aljuaid Meshal Khalid , Algarni Majed A. , Alzahrani Mohmmed S. , Alorfi Nasser M. , Alruqayb Wadia S. 
Published: February 2025

BackgroundSeasonal influenza vaccination is essential for reducing the risk and impact of influenza. Makkah region in Saudi Arabia, a destination for millions of pilgrims during Hajj and Umrah, presents a unique context for this study. Therefore, this research investigates the prevalence and influencing factors of influenza vaccine uptake among the public in Makkah region, Saudi Arabia.MethodThis cross-sectional study was conducted in Saudi Arabia between February and June 2024. The main researcher developed the questionnaire, which was reviewed by five academics and then piloted with 20 individuals for validation. An online questionnaire was used, targeting residents aged 18 and over with internet access. A snowball sampling method was applied. Data were collected via Google Forms and analyzed using SPSS version 26, employing descriptive statistics such as frequencies, percentages, and means.ResultsThe total number of respondents is 450 participants, with a response rate of 4.5%. Most respondents were male (71.1%) and aged between 18 and 30 years (44.5%). Education levels varied, with 57.5% holding a bachelor’s degree. Vaccination uptake showed 65.1% had received the vaccine, with 31.1% confident it is safe. Despite this, 58.8% did not get vaccinated this season. Confidence in the vaccine’s effectiveness was 59.5%, though 41.2% reported breakthrough infections. Accessibility was generally rated easy (57.7%). Social pressure (17.4%), trust in health institutions (36.9%), and COVID-19 concerns (36.7%) significantly influenced vaccination decisions. The likelihood of vaccination next season displayed polarized views.ConclusionThis study provides significant insights about vaccine hesitancy that may inform future research endeavors and practical applications. Understanding the various factors that impact the adoption of influenza vaccines offers valuable insights for developing targeted interventions and public health policies to improve vaccination rates. This study enhances theoretical understanding and practical strategies to encourage influenza vaccination, thereby improving public health initiatives in the area and beyond.
How does pole length affect lower back muscle activity at different inclines and skiing intensities during double poling?
Authors: Ohlsson Marie Lund , Nilsson Marcus , Swarén Mikael 
Published: February 2025

PurposeThis study aimed to investigate how pole length, incline, and skiing intensity affect lower back muscle activation in elite cross-country skiers. This addressing a critical gap in understanding the biomechanical demands and risk of low back pain of double poling (DP).MethodEleven elite cross-country skiers performed skiing trials on a treadmill, varying in incline (flat vs. 6°), intensity (two self-selected speeds, training speed and racing speed), and pole lengths. Muscle activity was measured by surface electromyography on the erector spinae thoracic and lumbar muscles, on the left and right side. A motion capture system was used for kinematic analysis of the lower back-pole moment arm and the hip angle during the DP cycle.ResultsCompared to men, female skiers had a significantly higher (p &lt; 0.001), overall muscle activation for the m. erector spinae lumbar on both the left and right side (26% of MVC vs. 15% of MVC, and 28% of MVC vs. 22% of MVC, for the left and right side, respectively). No correlations were found, neither between muscle activation to the lower back-pole moment arm, or to the hip angle.ConclusionThe findings suggest that female skiers experience significantly higher lumbar erector spinae activation during DP, potentially indicating greater susceptibility to back-related issues. The results also highlight the need to tailor training and right adapted equipment to mitigate lower back stress, especially in flat terrain high-intensity conditions. The asymmetrical muscle activity and gender differences underscores the need for further investigation into biomechanical factors influencing back muscle engagement in cross-country skiing.
Economic analysis of Agaricus bisporus mushrooms production and the perspective of sharing economy
Authors: Schilla Filip , Mumladze Gaga , Soukupova Jana , Smutka Luboš 
Published: February 2025

IntroductionUrban agriculture, particularly mushroom cultivation in basements, offers a sustainable solution to climate change, land scarcity, and food security challenges. This article explores the viability of cultivating Agaricus bisporus (white button mushrooms) in basements, while also considering the potential of a sharing economy business model to address these issues.MethodsWe simulate basement and ground-level room conditions, comparing factors such as temperature, humidity, light exposure, and air quality, which are crucial for mushroom growth. Economic calculations are also included to assess costs and profits, allowing for a comparison of feasibility and cost-effectiveness between the two environments.ResultsThe basement environment proves more favorable for mushroom cultivation, with stable temperatures and higher humidity reducing energy requirements. Economic analysis shows that basement cultivation has lower initial and operational costs compared to ground-level spaces.DiscussionBasement cultivation of Agaricus bisporus offers a sustainable solution for urban agriculture, addressing food security and land scarcity. Integrating this practice into a sharing economy model could further enhance its feasibility, contributing to environmental sustainability and economic growth in cities.
Short-term effects of brachycephalic obstructive airway syndrome surgery on fitness and exercise in brachycephalic dogs
Authors: Goossens Juliette , Meyer-Lindenberg Andrea , Zablotski Yury , Schroers Maike 
Published: February 2025

IntroductionBrachycephalic obstructive airway syndrome (BOAS) significantly impacts the physical fitness of affected dogs. This study aimed to assess changes in physical fitness, as measured by vital signs and salivary cortisol and vasopressin concentrations, before and after BOAS surgery using a standardized fitness test.MethodsA prospective clinical study was conducted on 35 brachycephalic dogs, including 13 Pugs, 21 French Bulldogs, and one English Bulldog. A preliminary examination included clinical anamnesis and a general examination. Physical fitness was evaluated using a submaximal treadmill test consisting of three 5-minute runs followed by a recovery phase. Vital signs were monitored throughout the test and saliva samples were taken before, immediately after and 15 min after the test. Eighteen animals underwent surgery due to moderate to severe BOAS symptoms, while 17 animals that were free of symptoms were assigned to the control group.ResultsOne month post-OP (post-operatively), dogs that underwent BOAS surgery exhibited significant improvement in physical fitness based on vital signs. However, they remained significantly less fit than the control group. No statistically significant changes were observed in salivary cortisol or vasopressin concentrations before and after surgery.DiscussionBOAS surgery reduces clinical symptoms and improves physical fitness, but affected dogs continue to exhibit substantial limitations. The consistency of cortisol and vasopressin levels across both groups reinforces the hypothesis of a stress-induced HPA-axis dysfunction, yet the limited number of evaluable samples and external influences suggest that salivary stress hormones alone may not reliably indicate surgical success. Future studies should incorporate additional biomarkers and clinical assessments to better understand the physiological impact of BOAS and its treatment.
Model-Based Optimization of the Field-Null Configuration for Robust Plasma Breakdown on the HL-3 Tokamak
Authors: He Muwen , Yang Bin , Chen Yihang , Xu Xinliang , Zhu Xiaobo , Yang Jiaqi , Sun Jiang , Liu Panle , Li Bo , Ji Xiaoquan 
Published: February 2025

This paper introduces a self-consistent field-null optimization algorithm of a poloidal magnetic field that precisely accounts for the influence of vacuum vessel eddy currents. Building on existing poloidal field (PF) coil currents, the algorithm can refine these waveforms to achieve various target field-null configurations. Firstly, based on the TokSys toolbox, a response model, including the PF coils and vacuum vessel circuits for the HL-3 tokamak, is developed under the MATLAB® and Simulink™ framework. The resistivity parameters of the model are calibrated using experimental data obtained from single-coil discharge tests. Subsequently, an iterative method was employed to simultaneously solve the dynamic field-null optimization problem within a specified spatial region and precisely account for the effect of passive eddy currents. Typically, B⊥≤1 G within a large area can be obtained with this iterative scheme, which can be stably sustained for over 15 milliseconds to ensure the robustness of breakdown. Finally, a low-pass filtered PID controller is applied to the model to achieve precise control of the PF coils currents, confirming the feasibility of implementing the proposed algorithm in real experiments.
Pemberdayaan Masyarakat melalui Menejemen Bank Sampah Berbasis Website
Authors: Supriyanti Yuni Indah , Imron Rosyadi  , Hania Sumarni  , Hevi Novriani  , Kevin Ardiansa  
Published: February 2025

Kemumu Village was originally in the form of a village named Sido Mulya from the Dutch Colonization Transmigration Program in 1935 which came from Banyumas, and Kebumen, Central Java. In 2023 Kemumu won 2nd place in the Competition and in 2024 won first place at the Provincial level. With this achievement, of course, the Village assisted by related parties such as TP-PKK and POKDARWIS must strive to create tourist locations to be cleaner, more beautiful, neat and comfortable to visit. However, this effort is not balanced by the awareness of visitors in throwing garbage. Visitors still throw garbage carelessly at interesting tourist spots. This makes tourist locations unbeautiful. Kemumu as a biowealth-based ecotourism destination and agrotourism with tourist spots in swampy areas are filled with a lot of garbage. This causes pollution, the flow of water is obstructed. The 2018 DRTPM PKM program has succeeded in forming a waste artisan center and has succeeded in improving community skills in utilizing plastic waste into goods of economic value. However, along with the increase in knowledge, understanding and behavior of the community in utilizing plastic waste, it has an impact on the lack of plastic waste supply needed by craftsmen. Meanwhile, the people of Kemumu have the potential to produce plastic waste. Through PMP 2024, it tries to provide solutions on how to manage plastic waste in order to create a sustainable tourism village, and increase awareness in waste management, increase knowledge, waste management skills so that it can meet the needs of waste artisans and community income with socialization, training, technology application, mentoring, and evaluation methods. The results of PMP 2024 have been able to increase the knowledge, understanding and skills of partners in managing plastic waste so that waste artisans no longer have difficulty in obtaining raw materials. The Arga Tirta Waste Bank has been formed which is located in the Palak Siring Kemumu Field
Efektivitas Program Jemput Bola Terpadu sebagai Upaya Mempercepat Pelayanan oleh Dinas Kependudukan dan Pencatatan Sipil Kabupaten Sidoarjo
Authors: Ascarya Padma Galuh , Hertati Diana 
Published: February 2025

Program Jemput bola Terpadu merupakan inovasi pelayanan publik yang dilakukan oleh Disdukcapil Kabupaten Sidoarjo sebagai Upaya untuk dapat mempercepat pelayanan yang dapat menjangkau seluruh masyarakat Kabupaten Sidoarjo mendapatkan pelayanan yang mudah dan cepat untuk mengurus kepemilikan dokumen kependudukan. Target dari program Jemput Bola Terpadu ini adalah seluruh desa yang berada di Kabupaten Sidoarjo, fokus utama dari program Jemput Bola Terpadu ini adalah desa yang masih memiliki persentase rendah kepemilikan dokumen kependudukan. Metode penelitian dalam penelitian ini menggunakan pendekatan kualitatif yang menjelaskan objek sesuai dengan fakta yang terjadi di lapangan, Tipe penelitian ini menggunakan tipe deskriptif yang menunjukkan gambaran yang terjadi di lapangan berdasarkan fakta yang ada di lapangan. Selain itu tujuan dari program Jemput Bola Terpadu yaitu untuk memberi pengetahuan tentang pentingnya mencatatkan peristiwa kependudukan. Dengan ini tujuan penelitian ini untuk mengetahui seberapa efektif program Jemput Bola Terpadu yang dianalisis menggunakan teori efektivitas milik Sutrisno yang meliputi a) Pemahaman program b) Tepat waktu c) Tepat sasaran d) Tercapainya tujuan e) Perubahan nyata.