bluuebunny/crossref_metadata_2025_split huggingface dataset:
TIPOLOGI FASAD RUMAH ADAT BATAK TOBA
Authors: Sihotang Koriana M. , Naibaho Polin DR , Aritonang Emmy Ria 
Published: October 2021

Batak Tobaâ€™s traditional houses is one of the relics of batak tribe tradition that up to now still many abandon the values ofÂ philosophy and beauty and create a natural picture that is considered to have soul. Batak traditional house is a building thatÂ characterizes the house or typical of the tribe of Batak which symbolizes the culture and characteristics of theÂ batakÂ community. Discussion in this research about typology facade of traditional Batak Toba house building in Tomok Village, HutaÂ Bolon and Huta Siallagan. Facade typology discussed in this research is the front view, the use of materials, dimensions, theÂ use of color, the placement of doors and windows of traditional houses of Batak Toba in Samosir. The research method usedin this research is qualitative, that is describing the existing condition data of facade design from some custom house of BatakÂ Toba which is located from three different villages namely Tomok Village, Huta Siallagan and Huta Bolon. Data analysis in thisÂ qualitative research is to search and arrange systematically data obtained from the results of field notes and documentationby organizing into categories, describing in units, synthesizing, arranging into patterns and making conclusions.
Willem Einthoven y su aporte a la Medicina
Authors: Padilla Cuadra Juan Ignacio 
Published: October 2021

Willem Einthoven, creador del electrocardiógrafo, nos permitió darle uso clínico al estudio de la actividad eléctrica cardiaca. Las mejoras que introdujo al galvanómetro de cuerda hicieron posible el uso de esta técnica como método diagnóstico universalmente reconocido. Se realiza una reseña biográfica de este científico incluyendo el desarrollo del electrocardiograma y situaciones de interés en relación con este invento.
Recocimiento de Electrocardiograma
Authors: Cairol Andres 
Published: October 2021

Paciente masculino de 52 años, conocido hipertenso, cardiópata, con antecedente de haber tenido un infarto agudo al miocardio hace 6 años, el cual hace 4 días fue sometido a una intervención quirúrgica para la colocación de un cardio desfibrilador. A su llegada al servicio de emergencias refiere que siente dolor en el sitio de la incisión donde le colocaron el desfibrilador y que además tiene leve dificultad para respirar. Es clasificado como CTAS II según la escala canadiense de triage y es valorado de manera inmediata por un médico el cual en el examen físico encuentra: paciente sin datos de dificultad para respirar, dolor en el sitio quirúrgico, más no en el resto del tórax consciente alerta, a la auscultación cardiaca presenta ruidos cardiacos con una frecuencia muy elevada y no se logra distinguir ningún soplo. Presenta murmullo vesicular normal y no hay datos de ruidos agregados. Los signos vitales al ingreso son: frecuencia cardiaca en 220 y sube a 250 por minuto, frecuencia respiratoria en 18, Presión arterial 96/ 50 mmHg.
Historia de la Medicina Frederic Foley: De Neurocirujano a Urólogo
Authors: Padilla Cuadra Juan Ignacio 
Published: October 2021

Federic Eugene Basil Foley fue un médico estadounidense quien inventó la sonda vesical que recibe su nombre. Inicialmente, tuvo interés en convertirse en neurocirujano mientras trabajaba junto a Harvey Cushing. Sin embargo, terminó dedicándose a la urología, donde realizó su mayor aporte.
Revisión de Farmacología de Urgencias ¿Cómo revertir el efecto de medicamentos anti trombóticos en sangrado grave?
Authors: Padilla Cuadra Juan Ignacio 
Published: October 2021

El uso frecuente de fármacos con efectos antitrombóticos obliga al médico encargado del servicio de emergencias a conocer exhaustivamente su farmacología y muy especialmente como revertir sus efectos. Cuando un enfermo se presenta con un sangrado que puede estar relacionado con algún medicamento que afecta la hemostasia es conveniente conocer el uso de antídotos específicos, factores de coagulación y algunos hemoderivados.
10 Recomendaciones para Tratar Neumonía Nosocomial
Authors: Padilla Cuadra Juan Ignacio 
Published: October 2021

La neumonía es una de las infecciones más frecuentes adquiridas a nivel nosocomial, especialmente la asociada a la ventilación mecánica. Para asegurar una mejor evolución del paciente es importante seguir ciertas reglas. Estas incluyen la escogencia inicial de tratamiento, tiempo de administración, descalación de antibióticos y, finalmente, el traslape a tratamiento oral cuando la condición del enfermo lo permite. En esta revisión se intenta contestar algunas de estas interrogantes según la evidencia disponible y se emiten recomendaciones prácticas en el manejo de la neumonía nosocomial.
Signo de Monte Fuji
Authors: Juan Ignacio  
Published: October 2021

Masculino 61 años, portador de un tumor invasivo de base de cráneo a nivel de fosa anterior es sometido a resección extensa del miso. Aunque en el postoperatorio inmediato cursa muy estable, se considera que es de alto riesgo de fístula de líquido cefalorraquídeo. Esto amerita colocación de drenaje lumbar externo. El paciente evoluciona hacia el deterioro del estado de conciencia por lo que se decide realizar tomografía axial de cabeza.
Troponinas cardiacas: Correlación entre el valor real y la injuria miocárdica
Authors: Vargas Fonseca Wadgner Antonio , Rojas Mora Erick José , Navas Gámez Daniela María 
Published: October 2021

Las troponinas son parte de estructuras miocárdicas que se liberan durante el proceso infarction de daño tisular generado por los diferentes tipos de infarto o de patologías que pueden llegar a producir un efecto deletéreo en la estructura muscular. Han formado parte de los diferentes métodos de diagnóstico e incluso de seguimiento, aunque el nivel de concentración definido no ha sido estandarizado. Además, se intenta hacer una correlación entre las diferentes isoformas y su utilidad a corto y largo plazo. Es por esto que es importante mantener la perspectiva de que los marcadores de daño miocárdico orientan al clínico en la objetividad diagnóstica.
Variability in reference evapotranspiration and moisture availability in three agroclimatic zones of Punjab, India
Authors: S. AATRALARASI  , P.K.KINGRA  , R.K.SETIA  , SOM PAL SINGH  
Published: October 2021

A research study was undertaken to estimate reference evapotranspiration (ETO), moisture index (MI) and aridity index (AI) and analyse their trends in different locations/zones of Punjab. Annual and seasonal ETO was observed to be highest in south-west and lowest in north-east zone. North-east zone experienced increasing trend in annual as well as seasonal ETO. Districts within the central zone had large variability within the zone. MI and AI were in the order of north-east zone followed by Central zone and South-west zone indicating better moisture availability conditions in north-east. Mean difference in annual and seasonal MI and AI also indicated statistical similarities within the districts of north-east and south-west zones but different from other zones. Thus, increasing trend of ETO in north-east region and higher ETO range in south-west zone along with severe moisture availability necessitates the need for more careful planning of water resources in the region.
Incidence forecasting of new invasive pest of coconut rugose spiraling whitefly (Aleurodicus rugioperculatus) in India using ARIMAX analysis
Authors: K.ELANGO  , S. JEYARAJAN NELSON  , P.DINESHKUMAR  
Published: October 2021

The rugose spiraling whitefly (RSW), Aleurodicus rugioperculatus Martin is a new invasive pest occurring in several crops including coconut since 2016 in India from Tamil Nadu, Karnataka, Kerala and Andhra Pradesh. The population dynamics of new invasive whitefly species, A. rugioperculatus study indicated that RSW was found throughout the year on coconut and the observation recorded on weekly interval basis shows that A. rugioperculatus population escalated from the first week of July 2018 (130.8 nymph/ leaf/ frond) reaching the maximum during the first week of October (161.0 nymph/ leaf/ frond) which subsequently dwindled to a minimum during April. Due to variation in the agro-climatic conditions of different regions, arthropods show varying trends in their incidence also in nature and extent of damage to the crop. Inﬂuence of weather parameters on rugose spiralling whitefly incidence is lacking, which is essential for developing management strategies. The forecasting model to predict rugose spiralling whitefly incidence in coconut was developed by ARIMAX model of weekly cases and weather factors. In exploring different prediction models by fitting covariates to the time series data, ARIMA (0,2,1) with Maximum temperature was found best model for predicting the rugose spiralling whitefly incidence and all covariates were found non-significant predictors except maximum temperature.
Population dynamics of aphid and coexisting predators in tomato agroecosystem
Authors: SHIVANI KHOKHAR  , KRISHNA ROLANIA  
Published: October 2021

Aphids generally attack vegetative plant parts, preferably leaves, and devitalize the plant by sucking the cell sap. Thorough knowledge of pest-predator ecology and their interaction is requisite to initiate timely pest management strategies. Therefore, we aimed to study the population dynamics of aphids and their predators on tomato in Hisar, Haryana during Rabi, 2016-17 and 2017-18. We observed two dominant aphid species viz., Aphis gossypii and Myzus persicae and three aphidophagous predator groups viz., coccinellids, spiders and syrphid fly maggots in the tomato agroecosystem. Aphid infestation started during the 9th standard meteorological week (SMW) and attained a peak during the 12th SMW (22.65 aphids per three leaves per plant). Aphid population exhibited highly significant negative correlation with minimum temperature (r= -0.917**), maximum temperature (r= -0.895**) and wind speed (r= -0.809**). However, it was positively correlated with morning relative humidity (r= 0.933**) and evening relative humidity (r= 0.856**). We used Principal component analysis (PCA) to reduce the dimensions of data and variables were transformed into principal components (PC) to explain the nature and extent of the relationships among different variables. PC1 and PC2 capture 57.6 and 20.3% of the variability in the data, respectively. Aphid predators exhibited a significant positive correlation with the prey population suggesting a positive density-dependent response.
Comunicación y populismo 2.0 en la nueva política española:
Authors: González Castro Jacob 
Published: October 2021

Objetivo: El objetivo principal de esta investigación consiste en analizar, desde el punto de vista de la Comunicación, el acercamiento que dos partidos de reciente creación en España, Unidas Podemos y Vox, ejercen hacia una corriente en auge en toda Europa: el populismo. Se pretende así detectar posibles semejanzas y diferencias en las que hayan podido incurrir ambas formaciones a este respecto.
Diseño/metodología/enfoque: Esta investigación analiza, mediante la técnica del análisis de contenido, las publicaciones que los dos partidos han realizado por medio de sus cuentas de Facebook y Twitter, acotando estas al período correspondiente a la campaña electoral que concluyó con la celebración de la primera de las dos elecciones generales que tuvieron lugar en España durante el año 2019, concretamente el 28 de abril.
Resultados: Los resultados confirman que, tanto Unidas Podemos como Vox, actúan como partidos que abrazan una nueva modalidad de populismo para llegar al mayor número de votantes posible. Adoptan, por tanto, una estrategia semejante, a pesar de sus diferencias ideológicas, cuyo antagonismo queda patente en la adaptación que cada uno de ellos hace de este pensamiento político.
Limitaciones/implicaciones: Las principales limitaciones de esta investigación se hallan en el número de partidos analizados, en las plataformas de comunicación estudiadas, así como en el período electoral. La ampliación de estas variables ofrecería, a su vez, un incremento de los resultados.
Originalidad/contribución: La aceptación que la sociedad española ha demostrado del populismo no conllevaba hasta ahora, y a diferencia de como ocurría en la mayor parte de los países de Europa, la entrada en el Congreso de un partido de ideología de extrema derecha. Un nuevo actor que llega, con una gran acogida por parte de la ciudadanía, para disputar un espacio al resto de formaciones, siguiendo la misma estrategia comunicativa que su mayor opositor.
Clasificación JEL: D72; D83
Assessment of antimycobacterial activities of pure compounds extracted from Thai medicinal plants against clarithromycin-resistantMycobacterium abscessus
Authors: Sirichoat Auttawit , Kham-ngam Irin , Kaewprasert Orawee , Ananta Pimjai , Wisetsai Awat , Lekphrom Ratsami , Faksri Kiatichai 
Published: October 2021

BackgroundInfection withMycobacterium abscessusis usually chronic and is associated with clarithromycin resistance. Increasing drug resistance is a major public-health problem and has led to the search for new antimycobacterial agents. We evaluated the antimycobacterial activity, toxicity, and synergistic effects of several plant secondary metabolites againstM. abscessus.MethodsTwenty-three compounds were evaluated for antimycobacterial activity against thirtyM. abscessusclinical isolates by broth microdilution to determine their minimum inhibitory concentration (MIC) values. Toxicity was evaluated using red and white blood cells (RBCs and WBCs). The compounds were used in combination with clarithromycin to investigate the possibility of synergistic activity.ResultsFive out of twenty-three compounds (RL008, RL009, RL011, RL012 and RL013) exhibited interesting antimycobacterial activity againstM. abscessus, with MIC values ranging from <1 to >128 μg/mL. These extracts did not induce hemolytic effect on RBCs and displayed low toxicity against WBCs. The five least-toxic compounds were tested for synergism with clarithromycin against seven isolates with inducible clarithromycin resistance and seven with acquired clarithromycin resistance. The best synergistic results against these isolates were observed for RL008 and RL009 (8/14 isolates; 57%).ConclusionsThis study demonstrated antimycobacterial and synergistic activities of pure compounds extracted from medicinal plants against clarithromycin-resistantM. abscessus. This synergistic action, together with clarithromycin, may be effective for treating infections and should be further studied for the development of novel antimicrobial agents.
Ultrasound Guided Femoral Nerve Block with Bupivacaine versus Bupivacaine and Tramadol for Postoperative Analgesia in Patients Undergoing Total Knee Arthroplasty under Spinal Anesthesia
Authors: Abo Farrag Mohammad Mostafa , Elahwal Laila , Maroof ElDomairy Hesham Mohammad , Okab Mohammad Ibrahem 
Published: October 2021

Background: Effective pain control in Total knee arthroplasty (TKA) is important for optimizing the rehabilitation process in order to achieve patient satisfaction with a good functional outcome as well as reduce hospitalization duration and costs. Combined use of aesthetic with tramadol has been reported to achieve a longer duration of sensory and motor block. The aim of this study is to evaluate the quality and duration of postoperative analgesia produced by ultrasound guided femoral nerve block (FNB) by bupivacaine versus (bupivacaine & tramadol) in patients undergoing total knee arthroplasty under spinal anesthesia.
Methods: This prospective randomized controlled double blinded study was carried out on 60 patients aged above 50 years; American Society of Anesthesiologists physical status (ASA) I-III scheduled for total knee arthroplasty under spinal anesthesia. Patients were randomized to one of two equal groups: Group I control (C): received FNB with 30 ml 0.25% bupivacaine. Group II tramadol (T): received FNB with 30ml 0.25% bupivacaine and 100 mg tramadol.
Results: Postoperative heart rate was significantly increased in group C than group T at 8h, 12h, 16h and 24h. Postoperative mean arterial blood pressure was significantly increased in group C than group T at 6h, 8h, 12h, 16h and 24h. There were 30 (100%) patients required rescue analgesia in group C and 19 (63.33%) patients in group T which was increased significantly in group C than group T. The time to first analgesic requirement was significantly decreased in group C than group T. Total morphine consumption was increased significantly in group C than group T. VAS was increased significantly in group C than group T at 6, 8, 12, 16 and 24 hours. Adverse effects were insignificantly different between both groups.
Conclusion: Adding tramadol (100 mg) to 0.25% bupivacaine (to a volume of 30 ml) during US guided FNB of TKA under spinal anesthesia was associated with better postoperative analgesia when compared with 0.25% bupivacaine alone.
In-vitro Study and In-vivo Predictions of Valsartan and Amlodipine Capsules through Micro Tablets
Authors: Binuraj K. , Sharma Maya , Zine Sandip 
Published: October 2021

Aim: The present research work was carried out to develop Valsartan and Amlodipine capsules using micro tablets and to evaluate the in-vitro drug release characteristics. The study was targeted to determine the systemic concentrations using in-vivo prediction.
Study Design: The in vivo parameters along with the marketed Valsartan and Amlodipine product was predicted using WinNonlin® software external prediction method.
Place and Duration of the Study: The present work was carried out at Pacific Academy of Higher Education and Research University, Udaipur between the duration of February-2019 to November-2019.
Methodology: The dissolution studies were performed for test and reference products in 900ml Phosphate buffer (pH 6.8), and the USP Type II apparatus at 50 RPM with a sinker. The in vivo pharmacokinetic prediction was performed using WinNonlin® Software. A mechanistic oral absorption model was built in Phoenix® WinNonlin® 8.2 software (Certara, Princeton, NJ, 08540, USA).
Results: The in-vitro dissolution studies were comparable between the test product and the reference product. The Similarity factor achieved was 61.7 and 84.8 for Amlodipine and Valsartan test product in comparison with the reference product. An average percent prediction error for Cmax and AUC for both Valsartan and Amlodipine achieved was less than 10% for all IVIVC models.
Conclusion: The relatively low prediction errors for Cmax and AUC observed strongly suggest that the Valsartan and Amlodipine IVIVC models are valid. The average percent prediction error of less than 10% indicates that the correlation is predictive and allows the associated dissolution data to be used as a surrogate for bioavailability studies.
A Study to Assess the Knowledge and Prevalence of Dialysis Induced Hypertension
Authors: Suthar Jineta , Yadav Daksha 
Published: October 2021

By knowing the level of knowledge of patients about risk factors of dialysis induced hypertension, we will be able to be aware that the patients reduce the risk factor affecting dialysis induced hypertension patients undergoing maintenance hemodialysis. So, the objective of the study were to assess the knowledge and prevalence of dialysis induced hypertension among patient’s undergoing maintenance hemodialysis. A qualitative research study was used. The participants was all the dialysis induced hypertensive patients undergoing maintenance haemodialysis, data collection was done using a questionnaires and checklist, 100 were completed the data. Data were analysed by descriptive and inferential statistics. And according to statistical analysis results, there was no significant relationship between the knowledge and risk factor of dialysis induced hypertension patients.
Background: Intradialytic hypertension is an increase in blood pressure during or immediately after hemodialysis which results in post-dialysis hypertension, is often largely ignored. Patients undergoing hemodialysis will possibly raise blood pressure, because the role of the kidneys in blood homoeostasis is impaired, risk factors like chronic volume overload and a range of other risk factors might also contribute to high blood pressure.
Objectives: The objectives of this study were as follows, 1. Assess the knowledge and prevalence of dialysis induced hypertension among patients undergoing haemodialysis.

Find out the association between risk factors and knowledge of dialysis induced hypertension among patients undergoing haemodialysis.

Results: The clinical significance of dialysis induced hypertension lies in the fact that each of these possible risk factors may contribute to the development of dialysis induced hypertension, out of 100 participants 4 (4%) were in the age group of 21 to 30 years, 16 (16%) were in the age group of 31 to 40 years, 36 (36%) were in the age of 41 to 50 years, 44 (44%) were in the age group of the year above. As regard Gender, 63 (63%) were male and 37 (37%) were females. As regards 92 (92%) were Married and 08(08%) were Unmarried. Regarding prevalence 50 (50%) had hypertension before and 50 (50%) had hypertension after the dialysis. Out of 100 patients, all 100 samples were had increased dry weight, 13 were had volume overload, 77 were had poor dietary salt restriction, 24 were had a family history of hypertension, nil have pulmonary oedema, 03 were had hyperthyroidism, 15 were had diabetes, 04 were had the cardio vascular disorder, 08 were had anaemia. Out of the 100 samples, 15% of the samples had poor, 85 % of the samples had average knowledge on dialysis induced hypertension. Thus, dry weight was present in the entire patient undergoing hemodialysis. Descriptive statistics were used to assess the mean, frequency and percentage, inferential statistics like the Chi-Square test was used to test for association.
The Cell‐Isolation Capsules with Rod‐Like Channels Ensure the Survival and Response of Cancer Cells to Their Microenvironment
Authors: Hui Lanlan , Wang Deng , Liu Zhao , Zhao Yueqi , Ji Zhongzhong , Zhang Man , Zhu Helen He , Luo Wenqing , Cheng Xiaomu , Gui Liming , Gao Wei‐Qiang 
Published: October 2021

AbstractCurrent macrocapsules with semipermeable but immunoprotective polymeric membranes are attractive devices to achieve the purpose of immunoisolation, however, their ability to allow diffusion of essential nutrients and oxygen is limited, which leads to a low survival rate of encapsulated cells. Here, a novel method is reported by taking advantage of thermotropic liquid crystals, sodium laurylsulfonate (SDS) liquid crystals (LCs), and rod‐like crystal fragments (LCFs) to develop engineered alginate hydrogels with rod‐like channels. This cell‐isolation capsule with an engineered alginate hydrogel‐wall allows small molecules, large molecules, and bacteria to diffuse out from the capsules freely but immobilizes the encapsulated cells inside and prevents cells in the microenvironment from moving in. The encapsulated cells show a high survival rate with isolation of host immune cells and long‐term growth with adequate nutrients and oxygen supply. In addition, by sharing and responding to the normal molecular and vesicular microenvironment (NMV microenvironment), encapsulated cancer cells display a transition from tumorous phenotypes to ductal features of normal epithelial cells. Thus, this device will be potentially useful for clinical application in cell therapy by secreting molecules and for establishment of patient‐derived xenograft (PDX) models that are often difficult to achieve for certain types of tumors, such as prostate cancer.