bluuebunny/crossref_metadata_2025_split huggingface dataset:
University students’ perceptions towards using exemplars dialogically to develop evaluative judgement: the case of a high-stakes language test
Authors: Chong Sin Wang 
Published: July 2021

AbstractThe revived interest in the notion of ‘evaluative judgement’ in higher education is motivated by commitment of researchers and practitioners to effectively implement learning-oriented assessment and cultivate this high-order cognitive ability to develop students’ capacity for self-regulated learning. Recent studies have examined the affordances and constraints of using exemplars to develop students’ evaluative judgement in the fields of Education, Nutrition, Biology, and English for Academic Purposes. The present study, which focuses on use of exemplars in IELTS, analyzes patterns of teacher-students dialogues and 129 university students’ perceptions of using exemplars to develop their understanding of assessment standards of IELTS academic writing tasks. Qualitative data were collected through an online questionnaire, individual semi-structured interviews, and workshop observations. Findings suggest that the IELTS instructor/researcher utilized various interactive strategies to develop students’ hard, soft, and dynamic dimensions of evaluative judgement. Students identified affordances and limitations of using exemplars for language test preparation. Implications related to dialogic exemplar use to develop students’ evaluative judgement are discussed in light of the findings.
The effect of 4-hexylresocinol administration on SCC-9 cells: mass spectrometric identification of proteins and cDNA microarray analysis
Authors: Kang Yei-Jin , Kim Seong-Gon 
Published: July 2021

Abstract
Background
In stress situations, bacteria produce dormancy-inducing factors to stop cell growth. The dormancy-inducing factors may have an inhibitory effect on tumor cell growth. Here we analyzed the differentially expressed protein profiles after 4-hexylresorcinol (4HR), one of the dormancy-inducing factors, administration using in vitro oral squamous carcinoma cells (SCC-9).

Method
The control group was SCC-9 cells culture without 4HR administration. The experimental group received 10 μg/mL of 4HR. Collected proteins from each group were loaded for 2D electrophoresis. Among the separated proteins, 20 differentially expressed proteins were selected and processed for LC-MS/MS.

Results
In proteomic analysis, the expression of keratin 1, keratin 10, and histone H2B were increased. In cDNA microarray assay, the genes related to the cellular differentiation (involucrin, keratin 13, 14) were highly expressed in the 4HR treated group (fold ratio > 2.0; Table 2). Interestingly, histone family was upregulated in the cDNA microarray assay.

Conclusion
The administration of 4HR on SCC-9 cells increased epithelial cell differentiation markers and histone.
Catheter-induced anaphylaxis and determination of the causative catheter in a patient undergoing neuroendovascular surgery: a case report
Authors: Sugiyama Yuki , Numata Kaori , Watanabe Natsuko , Urasawa Masatoshi , Murakami Toru , Murakami Ikuko , Koyama Jun-Ichi , Kawamata Mikito 
Published: July 2021

Abstract
Background
Anaphylaxis caused by a catheter itself used for endovascular surgery is rare, and a method for detection of a causative catheter has not been established. We report a case of catheter-induced anaphylaxis in which the causative catheter was successfully detected.

Case presentation
A 47-year-old male underwent neuroendovascular surgery. During surgery, blood pressure suddenly dropped and the level of tryptase indicated the occurrence of anaphylaxis. There were 24 candidate agents for the cause of anaphylaxis including 8 catheters. We performed the basophil activation test by directly mixing the catheter with blood. One catheter coated with a hyaluronic acid product showed a positive reaction, and we confirmed the result by a modified skin test using an elution solution of the catheter. Later, we successfully completed the neuroendovascular surgery without the catheter.

Conclusions
The methods used in this case can be useful for the detection of the causative agent in catheter-induced anaphylaxis.
Opportunities for dietitians to promote a healthy dietary intake in pregnant women with a low socio-economic status within antenatal care practices in the Netherlands: a qualitative study
Authors: Super Sabina , Beulen Yvette H. , Koelen Maria A. , Wagemakers Annemarie 
Published: July 2021

Abstract
Background
A healthy dietary intake during pregnancy is important for maternal and child health. However, pregnant women with a low socio-economic status often fail to meet dietary guidelines and requirements for healthy nutrition. Dietitians may play an important role in providing nutritional advice during pregnancy because midwives often experience a lack of nutritional knowledge, time and skills to provide adequate advice. However, there is limited research on the support that dietitians can offer in antenatal care practices for pregnant women. Therefore, this study aims to explore the opportunities for dietitians to support pregnant women with a low socio-economic status in concurrent antenatal care practices in the Netherlands.

Methods
In-depth interviews were conducted with 14 pregnant women with a low socio-economic status and 13 dietitians to identify barriers for healthy eating for pregnant women and the associated opportunities for dietitians to support these women in making healthy dietary changes.

Results
Four opportunities for dietitians to support pregnant women in making dietary changes could be discerned: (1) creating awareness of healthy and unhealthy eating patterns, (2) providing reliable and personally relevant information, (3) help identifying barriers and solutions for healthy eating and (4) making healthy eating manageable. Dietitians indicated that supporting pregnant women with a low socio-economic status in consuming a healthy diet requires the investment of sufficient time, effort and money.

Conclusions
Dietitians are trained and well-equipped to provide extensive support to pregnant women to promote a healthy dietary intake, especially when the complex interplay of barriers that pregnant women with a low socio-economic status experience for healthy eating needs to be addressed. In addition, there is a strong need for strengthening the collaboration between dietitians and midwives because midwives are the primary care provider for pregnant women in the Netherlands, but they often lack sufficient opportunities to provide adequate nutrition support. Strengthening this collaboration could promote that nutrition becomes a recurring and standard topic in antenatal care.
Principle of restoration ecology reflected in the process creating the National Institute of Ecology
Authors: Kim A. Reum , Lim Bong Soon , Seol Jaewon , Lee Chang Seok 
Published: July 2021

Abstract
Background
The creation of the National Institute of Ecology began as a national alternative project to preserve mudflats instead of constructing the industrial complexes by reclamation, and achieve regional development. On the other hand, at the national level, the research institute for ecology was needed to cope with the worsening conditions for maintaining biodiversity due to accelerated climate change such as global warming and increased demand for development. In order to meet these needs, the National Institute of Ecology has the following objectives: (1) carries out studies for ecosystem change due to climate change and biodiversity conservation, (2) performs ecological education to the public through exhibition of various ecosystem models, and (3) promotes regional development through the ecological industry. Furthermore, to achieve these objectives, the National Institute of Ecology thoroughly followed the basic principles of ecology, especially restoration ecology, in the process of its construction. We introduce the principles and cases of ecological restoration applied in the process.

Results
We minimized the impact on the ecosystem in order to harmonize with the surrounding environment in all the processes of construction. We pursued passive restoration following the principle of ecological restoration as a process of assisting the recovery of an ecosystem degraded for all the space except in land where artificial facilities were introduced. Reference information was applied thoroughly in the process of active restoration to create biome around the world, Korean peninsula forests, and wetland ecosystems. In order to realize true restoration, we pursued the ecological restoration in a landscape level as the follows. We moved the local road 6 and high-voltage power lines to underground to ensure ecological connectivity within the National Institute of Ecology campus. To enhance ecological diversity, we introduced perch poles and islands as well as floating leaved, emerged, wetland, and riparian plants in wetlands and mantle communities around the forests of the Korean Peninsula in the terrestrial ecosystem. Furthermore, in order to make the public aware of the importance of the intact nature, the low-lying landscape elements, which have disappeared due to excessive land use in most areas of Korea, was created by imitating demilitarized zone (DMZ) landscape that has these landscape elements.

Conclusions
The National Institute of Ecology was created in an eco-friendly way by thoroughly reflecting the principles of ecology to suit its status and thus the impact on the existing ecosystem was minimized. This concept was also designed to be reflected in the process of operation. The results have become real, and a result of analysis on carbon budget analysis is approaching the carbon neutrality.
Stereotactic cryoablation of large tumors of the sellar region with intraoperative CT scans—technical note
Authors: Patil Arun Angelo 
Published: July 2021

Abstract
Background
Cryoablation has been used by neurosurgeons in the past and is currently being used by other disciplines to treat kidney cancer, skin lesions, and cardiac conduction defects. Because the currently available cryogenic probes can safely create large lesions and the lesion generation (in the form of ice-ball) can be monitored on intraoperative CT images, cryoablation was used to treat large tumors in and around the sella. In this paper, the author describes a technique to perform this procedure.

Main body
Three large tumors in 3 patients were treated with this method. Age of the patients was 26–58 years with a male/female ratio of 2/1. Patient 1 had a non-secreting pituitary adenoma (measuring 8 × 8 cm) and presented with long-standing total visual loss in both eyes, severe headache, and seizures. She had previous resection and radiation therapy. Patient 2 had prolactinomas (measuring 5.1 × 4.6 cm) and presented with progressive loss of vision and diplopia. Patient 3 had recurrent craniopharyngioma (measuring 7.2 × 5 cm) with prior treatment with resection radiation and frequent drainage of the cyst. He presented with headache and progressive worsening of his vision.
The procedure was done on the CT table with intraoperative scans, using Patil stereotactic frame and argon cryoablation probe (Healthtronics). 3-D images were used to plan targets and trajectories. The probe was placed at the target via a trans-nasal trans-sphenoidal route. One to 3 lesions measuring 2.5–3 cm in diameter were made to ablate the tumor. Ice-ball formation was monitored live on CT images.
There is no complication. One patient had near-complete resolution of the tumor, two had partial resolution of their tumors, and all had resolution of their presenting symptoms at follow-up of 3–24 months (median 6 months). In one patient, symptoms reoccurred due to the formation of new tumor masses.

Short conclusion
Cryoablation of intracranial tumors and can be done safely and effectively. Live monitoring of lesion generation using CT imaging is a major advantage of this technique.
The journey of polycarbonate-based composites towards suppressing electromagnetic radiation
Authors: Sushmita Kumari , Madras Giridhar , Bose Suryasarathi 
Published: July 2021

Abstract
Electronic devices’ widespread usage has led to a new form of pollution, known as electromagnetic (EM) pollution, causing serious problems like equipment malfunctioning and affecting its reliability. This review article presents a comprehensive literature survey on the various polycarbonate (PC)-based materials for electromagnetic interference (EMI) shielding applications comprising of PC-based composites, blend composites, foams, and more recently, multilayered architectures. Following the state-of-the-art literature available from the previous decade, it is apparent that the properties (conductivity, permittivity and permeability) of nanofiller/fillers and nanocomposite processing/fabrication techniques control the EMI shielding properties in PC-based materials. Researchers have explored a variety of fillers, but high aspect ratio carbonaceous nanofillers have gained significant attention. Through morphological modifications of PC composites, one can obtain a percolation threshold as low as 0.021 wt% of carbon nanotubes (CNTs). However, higher connectivity of conductive filler need not necessarily lead to high EMI shielding performance. Thus, detailed insight into the shielding mechanism is also highlighted. This review article will help researchers design PC-based materials with superior EMI shielding performance coupled with good mechanical stability.

Graphical abstract
Bacterial gastroenteritis in children below five years of age: a cross-sectional study focused on etiology and drug resistance of Escherichia coli O157, Salmonella spp., and Shigella spp.
Authors: Uddin Mohammad Sharif , Rahman Md. Mijanur , Faruk Md. Omar , Talukder Asma , Hoq Md. Imranul , Das Suman , Islam K. M. Shariful 
Published: July 2021

Abstract
Background
Gastroenteritis is a common infectious disease in children, which results in high mortality and morbidity, especially in resource-poor countries. This study presents the selected main gastroenteritis causing bacteria, including Escherichia coli O157, Salmonella and Shigella species delineating their prevalence and resistance pattern to the clinically used antibiotics.

Results
A total of 346 stool specimens from children of clinically suspected gastroenteritis below five years have been obtained, and bacterial pathogens were recovered using selective media, biochemical and serologic tests. We found that 35 (10%) of them were confirmed bacterial gastroenteritis (BGE) with either Escherichia coli O157 (14%), Salmonella spp. (43%), and Shigella spp. (43%). Nevertheless, the prevalence of E. coli O157, Salmonella spp., and Shigella spp. in this study were documented as 1.45%, 4.34%, and 4.34%, respectively. Moreover, 2 (40%) of E. coli O157, 4 (26.67%) of Salmonella spp., and 14 (93%) of the Shigella spp. were found as multidrug-resistant. Nonetheless, Shigella spp. isolates showed 100%, 87%, and 73% resistance to cotrimoxazole, ciprofloxacin, and azithromycin respectively, while E. coli O157 showed 80% resistance to cotrimoxazole and 60% to ciprofloxacin and azithromycin. On the contrary, cotrimoxazole, ciprofloxacin, azithromycin, and tetracycline were resistant in 40%, 47%, 27%, and 53% of Salmonella spp. isolates respectively.

Conclusion
These findings generate significant insights on the prevalence and antibiotic resistance of the three major gastroenteritis causing bacteria in the study area. Therefore, it will help physicians and policymakers selecting the right antibiotics in essential cases, particularly, reevaluation of recommending cotrimoxazole, ciprofloxacin, and azithromycin in the management of bacterial gastroenteritis.
Transcription factor UvMsn2 is important for vegetative growth, conidiogenesis, stress response, mitochondrial morphology and pathogenicity in the rice false smut fungus Ustilaginoidea virens
Authors: Xu Yuandi , Wu Shuang , Yu Zhaomeng , Moeketsi Emily Kolojane , Yang Zhixiang , Zhang Zhengguang , Zhang Haifeng 
Published: July 2021

AbstractTranscription factors (TFs) play critical roles in the control of development and pathogenicity of phytopathogens by directly or indirectly regulating the expression of downstream genes. Here, we identified and characterized a zinc finger TF UvMsn2 in Ustilaginoidea virens, a homolog of MoMsn2 from the rice blast fungus. Heterogenous complementation assay revealed that UvMsn2 fully restored the defects of the ∆Momsn2 mutant in vegetative growth, conidiation and pathogenicity. Deletion of UvMsn2 in U. virens led to a reduction of the pathogen in vegetative growth, aerial hyphae and conidiation. Additionally, the ∆Uvmsn2 mutant displayed defects in conidial morphology and germination, as well as mitochondrial morphology. Pathogenicity and toxicity assays revealed that the ∆Uvmsn2 mutant was non-pathogenic and less inhibitory to rice seed germination. The ∆Uvmsn2 mutant showed different sensitivity to various stresses. Further microscopic examination found that UvMsn2 was localized in both cytosol and nucleus, and translocated from cytosol to nucleus under the treatment of NaCl. Our results demonstrate that UvMsn2 is a critical TF that regulates the vegetative growth, conidiogenesis, stress response, mitochondrial morphology and virulence in the rice false smut fungus.
Maize catalases localized in peroxisomes support the replication of maize chlorotic mottle virus
Authors: Jiao Zhiyuan , Wang Juan , Tian Yiying , Wang Siyuan , Sun Xi , Li Siqi , Ma Wendi , Zhou Tao , Fan Zaifeng 
Published: July 2021

AbstractCo-infection of maize chlorotic mottle virus (MCMV) with a virus in the Potyviridae family, such as sugarcane mosaic virus, usually leads to maize lethal necrosis (MLN). Over the past decade, MCMV/MLN has emerged in many countries/regions of the world and resulted in serious yield loss in maize production. Although partial functions of some MCMV-encoded proteins have been identified, the host factors related to MCMV replication are poorly understood. Here, we show that maize peroxisomes can form aggregated bodies in MCMV-infected leaf cells. The dsRNA binding-dependent fluorescence complementation assay indicated that the aggregated peroxisomes in maize served as the major replication site of MCMV. In addition, our results revealed that all the three maize catalases were present mostly in peroxisomes in the presence or absence of MCMV. Furthermore, we determined that inhibition of catalase activity or induction of reactive oxygen species (ROS) in maize protoplasts significantly reduced the accumulation of MCMV RNA. In summary, this research reveals the replication site of MCMV and an important role of maize catalases in supporting virus replication. Our results are conducive to understanding the pathogenesis of MCMV and identifying targets for resistance breeding or gene regulation strategies.
Seizure frequency and obstetric complications at advanced maternal age: a preliminary observational study in women with epilepsy
Authors: Gao Hui , Hao Nanya , Liu Shanrui , Zhou Dong 
Published: July 2021

Abstract
Background
Seizure control during pregnancy and obstetric outcomes are of important concerns for women with epilepsy (WWE) and their families. Advanced maternal age (≥35 years) shows a growing trend in the society with changes of lifestyle, which also occurs in diseased populations. The advanced maternal age is an independent factor for some unsatisfying obstetric outcomes. In this study we explored the seizure control and obstetric complications associated with advanced maternal age in WWE.

Methods
This study was based on the epilepsy pregnancy registry at West China Hospital. Patients with epilepsy in this registry who were aged 35 or older when starting pregnancy were included in this study. Their basic demographics and detailed information on epilepsy management and obstetric issues in all trimesters and during 1-year follow-up after birth were documented and reviewed. Data were processed by IBM SPSS version 22.0. The demographic characteristics, seizure frequency, treatment change, obstetric complications, and outcomes were analyzed and compared.

Results
Fifteen patients were included in this study, with an average age of 36.32 ± 2.39 years at pregnancy, and 73.33% of them were primiparas. The change of seizure frequency during pregnancy was not in a clear pattern, but there was an increased incidence of tonic-clonic seizures during the mid- and last trimesters. More than 20% of the patients had obstetric complications throughout the trimesters, including vaginal bleeding, hypothyroidism, and pre-eclampsia. The pre-eclampsia seemed extraordinarily complicated with other conditions. However, none of the complications were related with malformations or poor outcome of babies after 1-year follow-up.

Conclusion
Advanced maternal age combined with WWE is associated with frequent common obstetric complications. Future controlled studies with large sample sizes are needed to explore the related risks in comparison with other WWE and non-epileptic populations.
The link between broiler flock heterogeneity and cecal microbiome composition
Authors: Lundberg Randi , Scharch Christian , Sandvang Dorthe 
Published: July 2021

Abstract
Background
Despite low genetic variation of broilers and deployment of considerate management practices, there still exists considerable body weight (BW) heterogeneity within broiler flocks which adversely affects the commercial value. The purpose of this study was to investigate the role of the cecal microbiome in weight differences between animals. Understanding how the gut microbiome may contribute to flock heterogeneity helps to pave the road for identifying methods to improve flock uniformity and performance.

Results
Two hundred eighteen male broiler chicks were housed in the same pen, reared for 37 days, and at study end the 25 birds with highest BW (Big) and the 25 birds with lowest BW (Small) were selected for microbiome analysis. Cecal contents were analyzed by a hybrid metagenomic sequencing approach combining long and short read sequencing. We found that Big birds displayed higher microbial alpha diversity, higher microbiome uniformity (i.e. lower beta diversity within the group of Big birds), higher levels of SCFA-producing and health-associated bacterial taxa such as Lachnospiraceae, Faecalibacterium, Butyricicoccus and Christensenellales, and lower levels of Akkermansia muciniphila and Escherichia coli as compared to Small birds.

Conclusion
Cecal microbiome characteristics could be linked to the size of broiler chickens. Differences in alpha diversity, beta diversity and taxa abundances all seem to be directly associated with growth differences observed in an otherwise similar broiler flock.
Acute pulmonary embolism in a patient with hepatitis C virus infection and hepatocellular carcinoma: a case report
Authors: Abdelnabi Mahmoud , Saleh Yehia , Almaghraby Abdallah , Tok Özge Özden , Abdelgawad Hoda , ElSamad Sherif Abd 
Published: July 2021

Abstract
Background
Cardiac metastases in hepatocellular carcinoma patients are infrequently encountered and usually associated with a very poor prognosis.

Case presentation
Hereby, we report a case of an acute pulmonary embolism (PE) on top of HCC with direct cardiac invasion to the right atrium (RA) through the inferior vena cava with another metastasis to the right ventricular apex in the form of highly mobile cauliflower mass protruding through the tricuspid valve into RA and nearly obliterating right ventricular outflow tract in a multi-centric hepatocellular carcinoma patient.

Conclusion
Acute dyspnea in a patient with a long history of hepatitis C virus infection raises the suspicion of acute PE due to either hypercoagulable state induced by malignancy or by cardiac extension of the tumor which usually carries high mortality rates. To the best of our knowledge, this case is the first case in the literature to show cardiac metastases in HCC with two different pathological mechanisms.