bluuebunny/crossref_metadata_2025_split huggingface dataset:
Information and Scientific Impact of Advanced Therapies in the Age of Mass Media: Altmetrics-Based Analysis of Tissue Engineering
Authors: Santisteban-Espejo Antonio , Martin-Piedra Miguel Angel , Campos Antonio , Moran-Sanchez Julia , Cobo Manuel J , Pacheco-Serrano Ana I , Moral-Munoz Jose A 
Published: July 2021

Background
Tissue engineering (TE) constitutes a multidisciplinary field aiming to construct artificial tissues to regenerate end-stage organs. Its development has taken place since the last decade of the 20th century, entailing a clinical revolution. TE research groups have worked and shared relevant information in the mass media era. Thus, it would be interesting to study the online dimension of TE research and to compare it with traditional measures of scientific impact.

Objective
The objective of this study was to evaluate the online dimension of TE documents from 2012 to 2018 using metadata obtained from the Web of Science (WoS) and Altmetric and to develop a prediction equation for the impact of TE documents from altmetric scores.

Methods
We analyzed 10,112 TE documents through descriptive and statistical methods. First, the TE temporal evolution was exposed for WoS and 15 online platforms (news, blogs, policy, Twitter, patents, peer review, Weibo, Facebook, Wikipedia, Google, Reddit, F1000, Q&A, video, and Mendeley Readers). The 10 most cited TE original articles were ranked according to the normalized WoS citations and the normalized Altmetric Attention Score. Second, to better comprehend the TE online framework, correlation and factor analyses were performed based on the suitable results previously obtained for the Bartlett sphericity and Kaiser–Meyer–Olkin tests. Finally, the linear regression model was applied to elucidate the relation between academics and online media and to construct a prediction equation for TE from altmetrics data.

Results
TE dynamic shows an upward trend in WoS citations, Twitter, Mendeley Readers, and Altmetric Scores. However, WoS and Altmetric rankings for the most cited documents clearly differ. When compared, the best correlation results were obtained for Mendeley Readers and WoS (ρ=0.71). In addition, the factor analysis identified 6 factors that could explain the previously observed differences between academic institutions and the online platforms evaluated. At this point, the mathematical model constructed is able to predict and explain more than 40% of TE WoS citations from Altmetric scores.

Conclusions
Scientific information related to the construction of bioartificial tissues increasingly reaches society through different online media. Because the focus of TE research importantly differs when the academic institutions and online platforms are compared, basic and clinical research groups, academic institutions, and health politicians should make a coordinated effort toward the design and implementation of adequate strategies for information diffusion and population health education.
A Deep Neural Network for Estimating Low-Density Lipoprotein Cholesterol From Electronic Health Records: Real-Time Routine Clinical Application
Authors: Hwang Sangwon , Gwon Chanwoo , Seo Dong Min , Cho Jooyoung , Kim Jang-Young , Uh Young 
Published: July 2021

Background
Previously, we constructed a deep neural network (DNN) model to estimate low-density lipoprotein cholesterol (LDL-C).

Objective
To routinely provide estimated LDL-C levels, we applied the aforementioned DNN model to an electronic health record (EHR) system in real time (deep LDL-EHR).

Methods
The Korea National Health and Nutrition Examination Survey and the Wonju Severance Christian Hospital (WSCH) datasets were used as training and testing datasets, respectively. We measured our proposed model’s performance by using 5 indices, including bias, root mean-square error, P10-P30, concordance, and correlation coefficient. For transfer learning (TL), we pretrained the DNN model using a training dataset and fine-tuned it using 30% of the testing dataset.

Results
Based on 5 accuracy criteria, deep LDL-EHR generated inaccurate results compared with other methods for LDL-C estimation. By comparing the training and testing datasets, we found an overfitting problem. We then revised the DNN model using the TL algorithms and randomly selected subdata from the WSCH dataset. Therefore, the revised model (DNN+TL) exhibited the best performance among all methods.

Conclusions
Our DNN+TL is expected to be suitable for routine real-time clinical application for LDL-C estimation in a clinical laboratory.
Subsurface Geology and Hydrothermal Alteration of The Patuha Geothermal Field, West Java: A Progress Report
Authors: Utama Peter Pratistha 
Published: July 2021

Patuha geothermal field is one of the geothermal fields in West Java. Developed by PT Geo Dipa Energi (Persero) since 2014, the geothermal field produced electricity, with installed capacity amounted to 55 MWe. Patuha geothermal system is vapour-dominated system. The geothermal manifestations are located at approximately 2,100 m asl. The Patuha field consists of three main upflow zones, namely Kawah Putih, Kawah Ciwidey, and Kawah Cibuni. This study analyzed the drill cuttings from 3 wells as the primary data with total depths ranging from 1,581 to 2,166 m with the well’s highest stable temperatures measured of ±230°C. The three wells selected for this research—PPL 02, PPL 04, and PPL 07—were analyzed to describe the rock properties and estimate the prospect areas of present-day geothermal exploration in Patuha. The objective of this paper is to develop a better understanding of the subsurface geology and its correlation to the dynamic processes (i.e., hydrothermal alteration) in Patuha geothermal field. The hydrothermal minerals are formed by near-neutral pH fluids and are characterized by quartz, calcite, clays (smectite, illite, chlorite), wairakite, epidote, and actinolite. The existence of acidic fluids is evident by the formation of acidic hydrothermal minerals e.g., anhydrite at various depth of the studied wells, particularly at PPL 07 which is located around Sugihmukti-Urug area. Moreover, the previous studies by Reyes (1990), Layman and Soemarinda (2003), Rachmawati et al. (2016), Elfina (2017) on hydrothermal minerals, geothermal manifestation characteristics, fluid geochemistry, and conceptual model are adapted to improve the analysis and interpretation of this paper.
La metáfora de la confrontación y los argumentadores razonables
Authors: Gascón José Ángel 
Published: July 2021

Las discusiones argumentativas comúnmente se describen en términos confrontativos, pero no está claro que la argumentación sea necesariamente confrontativa. Aquí argumento que la confrontación no es un elemento esencial de la argumentación y de hecho debe evitarse porque desalienta el comportamiento razonable. La razonabilidad, caracterizada aquí como una disposición a modificar las creencias propias ante buenos argumentos, es puesta en peligro por las metas confrontativas. Eso nos da una razón para rechazar la confrontación en la argumentación, pues la razonabilidad contribuye a algunos de los mayores bienes que la argumentación puede producir.
Experimentos de soborno desde la perspectiva de su validación de constructo
Authors: Senci Carlos Maximiliano 
Published: July 2021

El artículo desarrolla un desafío a la validez de constructo de los experimentos de soborno consistente en que las motivaciones sociales no supervienen meramente de las características intrínsecas de los individuos, sino que dependen de factores contextuales, particularmente normativos, que otorgan contenido a dichas motivaciones. El déficit teórico que presenta el constructo de soborno se evidencia en una incompleta teorización de dicha dimensión normativa en la operacionalización del constructo de soborno, lo que se traduce en la falta de inclusión de operaciones que representen dicha dimensión a nivel concreto de la parametrización y la búsqueda de correlatos empíricos.
On The Legal Sanction Against Marriage Registration Violation in Southeast Asia Countries: A Jasser Auda’s Maqasid Al-Shariah Perspective
Authors: Harisudin M Noor , Choriri Muhammad 
Published: July 2021

The legal sanction on marriage registration violations was intended to create equity within households and fulfill every citizen’s constitutional rights. However, the law enforcement efforts encountered some problems, especially in three Southeast Asia countries: Indonesia, Malaysia, and Brunei Darussalam. This article investigated the diversity of regulations on marriage registration violations in the countries and analyzed how Jasser Auda’s maqasid al-shariahperspective viewed the type of legal sanctions there. This study found that there were regulations on marriage registration violations in each country. However, while Malaysia and Brunei Darussalam imposed both financial penalty and imprisonment, Indonesia only charged fines for the culprits. In Jasser Auda’s perspective, the regulations in the countries, except Indonesia, were in line with maqasid al-shariah because firstly, they aimed at maintaining harmony in marriage and contained the aspect of serving the depth and breadth of public interest (maslahah) in terms of necessities (daruriyat). Secondly, the regulations had traversed basic conceptual approach and systems analysis.
HISTÓRIA DA ÁFRICA E DA CULTURA AFRO-BRASILEIRA: O QUE DIZEM OS PROFESSORES DE HISTÓRIA E OS JOVENS ESTUDANTES
Authors: Nogueira Camilla , Silva Júnior Astrogildo Fernandes 
Published: July 2021

O presente texto apresenta resultados finais de uma dissertação que foi desenvolvida no Programa de Pós-graduação em Educação pela Universidade Federal de Uberlândia (PPGED/UFU). Tem como objetivo identificar e refletir sobre as formas que conteúdos relacionados à História da África e cultura afro-brasileira vem sendo trabalhada na Escola Municipal Machado de Assis, localizada no município de Ituiutaba, MG, Brasil. Trata-se de uma pesquisa qualitativa que recorreu a diferentes instrumentos: a observação das aulas de História e confecção de notas de campo, a técnica do grupo focal e a entrevista com os professores de História. Acredita-se que essa investigação possa colaborar com a formação dos professores de História e suas práticas em sala de aula, sobretudo o que tem sido produzido no campo epistemológico da lei 10.639/03.
Aktivitas Sitotoksik dan Antiproliferasi Fraksi n-Heksan Biji Al-pukat (Percea americana Mill.) Terhadap sel T47D
Authors: Rahmawati Juwita , Maryati Maryati 
Published: July 2021

Avocado plants are widely used as traditional medicine in Indonesia. This research aimed to determine the cytotoxic and antiproliferation activity of avocado seed extract and fractions on the T47D breast cancer cell line. Extraction was done by maceration method using 96% ethanol, then fractionation was done by liquid-liquid partition using n-hexane, chloroform, and ethyl acetate. Cytotoxic and antiproliferation tests were done by the MTT method. Apoptosis activity was investigated by the double staining method, using acridine orange-propidium iodide as a staining reagent. Results showed that the n-hexane fraction of avocado seed had a cytotoxic activity with IC50 27.9 µg/mL. N-hexane fraction of avocado seed inhibited proliferation and induced apoptosis of T47D cell line.
Production of Disease-Free Olive Seedlings with Artificial Intelligence and Biotechnological Methods
Authors: Galatali S. , Balci M. A. , Akguller O. , Kaya E. 
Published: July 2021

It is an inevitable fact that the applications of machine learning and artificial intelligence technologies in agricultural biotechnology approaches, whose applications are increasing rapidly in almost every field, will have an important place in determining the future fate of agriculture. Applications in which artificial intelligence is adapted to biotechnological processes such as breeding, in vitro culture studies, germplasm preservation, disease-free plant production, genetic transformation, and other genetic analyzes are becoming increasingly common. In the current study is highlighted the potential benefits between artificial intelligence and agricultural technologies. As with many plant species, viral diseases have negative effects on fruit yield, life span, and quality of olive varieties, which are important in economy. Elimination of viruses from the plant with traditional methods is quite laborious, takes a lot of time, and often fails to produce successful results. However, new protocols have been developed to eliminate persistent pathogens. These protocols include techniques such as heat application (thermotherapy), chemical therapy (chemotherapy), tissue culture methods (meristem culture). When these techniques are applied alone or together, it may be possible to obtain anti-virus plants. Artificial intelligence technology will make it possible to benefit from the method to be used in the most efficient way by revealing which of these biotechnological methods can be used in the most effective and optimal conditions, and the possible advantages and disadvantages as a result of comparing with others.
The Impact of Maternal, Perinatal, and Early Infancy Period on the Eruption Timing of the First Primary Tooth
Authors: Georgiadou Aikaterini I. , Ritsas Athanasios , Arhakis Aristidis 
Published: July 2021

Aim: The aim of this study is to identify and review the literature on effect of perinatal and early infancy factors on the eruption chronology of the first deciduous tooth.
Materials and methods: A PubMed database literature survey regarding the influence of maternal, perinatal and early infancy period factors on eruption timing of the first primary tooth covering the period from January 1964 to 2020 was conducted.
Results: Maternal factors such as smoke exposure during pregnancy, gestational age or even Vitamin D levels could possibly affect the eruption timing. Strong association was evident between some perinatal factors like infant’s birth weight or ethnicity and primary teeth eruption chronology, as opposed to infant’s birth length or sex. Many studies indicated that prematurity could lead to delayed eruption timing, while other studies do not confirm that allegation. Additionally, weight gain during early infancy period seems to have a great effect on eruption timing, whereas feeding method’s impact is not clarified yet.
Conclusion: Eruption timing of the first primary tooth is not influenced by only one specific factor. Several conditions may act together and increase the risk of delayed or accelerated teeth eruption, occurring additively or even synergistically. The association between perinatal and early infancy factors and eruption timing of the first primary tooth needs further controlled studies as well as research in a wider spread of ethnicities.
Data on Biogas Production Quality: Evidence from the Wastewater Treatment Plant of Durrës
Authors: Sefa Stela , Floqi Tania , Sefa Julian 
Published: July 2021

The wastewater treatment plant (WWTPD) located in Durrës, responsible for a treatment area of 205,000 inhabitants, employs the tertiary advanced wasterwater treatment to generate biogas from activated sludge for self use. The biogas collected from the anaerobic digestion tank feed the boiler and the co-generation unit which is then transformed to power its own energy grid. In order to evaluate the quality of biogas produced by anaerobic digestion of WWTPD’s sludge, is measured the percentage of CH4 and CO2 from the biogas production during a three years period (2016 – 2018).
From the performed analyses has resulted a percentage of CH4 up to 75% and 25% CO2 in 2016. While the lowest percentage of CH4 in 2018 with respectively 70% CH4 and 30% CO2.
Based on the value measurements, qualitative results of biogas parameters show that physicochemical and biochemical processes are performed under strict conditions and anaerobic digestion is performed according to standards.
Method of kurtosis in estimating the measurement uncertainty during calibration of the electrical resistance measures using a potentiometer
Authors: Zakharov Igor , Botsiura Olesia , Semenikhin Valerii 
Published: July 2021

Calibration of electrical resistance measures is considered by the indirect method, which is realized through measuring the voltage drop across the series-connected reference and calibrated resistors. The biases of the estimates of the measurand and the combined standard uncertainty due to the nonlinearity of the measurement model were calculated. The distribution laws of the input quantities in the calculation of the expanded uncertainty were taken into account by the kurtosis method. An example of measurement uncertainty evaluating during calibration of single-size electrical resistance measure R331 with a nominal resistance of 1000 Ω by comparing its value using a potentiometer R345 with the value of the calibrated reference standard is considered. Estimates of the measurand and its standard and expanded uncertainties obtained using the proposed method showed good agreement with the estimates obtained using the Monte Carlo method.
Reliable instrumental metering of natural gas is the key to Ukraine’s energy independence
Authors: Kovalenko Alina 
Published: July 2021

By virtue of geographical and historic factors, Ukraine has been playing an important role in oil and natural gas deliveries to European energy markets. Such status is basically attributed to the fact that West and Central European countries, while being rather big consumers of natural hydrocarbons, have shortage in their own energy resources.
On the other hand, major natural gas and oil reserves are concentrated in the Russian Federation, Caspian region and the Gulf area. Currently Ukraine has become a major juncture in the transit of gas and oil from Russia and Kazakhstan to European markets. The expected increase in consumption of natural hydrocarbon resources, as well as their uneven distribution make Ukraine, owing to its suitable geographical location and the developed gas and oil network, an “energy bridge” between the exporting countries and consumers in the industrialized Europe.
In the article the author considers the modern gas supply system of Ukraine. The author carried out a study on the technical feasibility of calibration of flow meters on the environment of natural gas under pressure. Currently in Ukraine calibration is performed only in the air. This does not make it possible to reduce the error in the instrumentation of natural gas. Given the volume of natural gas consumption in the country (about 20 billion m3/year), this leads to huge non-production losses, negative impact on economic performance and inflated cost for end users. The European experience was analyzed: PTB, DNV, PIGSAR, SICK, INOTECH. Modernization of the gas industry of Ukraine is proposed.
Duhamel Procedure untuk Hirschsprung’s Disease Anak di RS Syaiful Anwar Malang
Authors: Wibowo Herry 
Published: July 2021

Abstract— The diagnosis of Hirschprung's disease is made with barium enema and rectal biopsy in full thickness. The Duhamel procedure was performed in 8 cases in 2008 for cases of Hirschsprung's disease. Age range of patients 7 months to 11 years. The average body weight when operated on is 7-21 kg. Morbidity and mortality after surgery were not launched. Anorectal myectomy with low anterior resection, the Duhamel-Martin procedure, and the Soave pull-through endorectal procedure are the most acceptable methods for surgical management. Hirschsprung's disease was treated in Syaiful Anwar Hospital Malang in 2008 with the following data: 1 person in January (1 year), 1 person in February (6 years), 1 person in March (7 years), 3 people in April ( 7 months, 4 years and 2 years), 2 people in August 2008 (7 months and 11 years). Enlarged abdomen with bloating, repeated constipation and sometimes aborted. Withdrawal procedures that work with endorectal withdrawal procedures, all show long results
Keywords: duhamel technique, hirschsprung's disease, constipation, infant

Abstrak— Diagnosis penyakit Hirschprung dibuat dengan barium enema dan full-thickness rectal biopsy. Duhamel procedure telah dilakukan pada 8 kasus pada tahun 2008 untuk kasus Hirschsprung's disease. Rentang usia penderita 7 bulan hingga 11 tahun. Berat badan rata – rata saat dioperasi 7 – 21 kg. Morbiditas dan mortalitas setelah operasi tidak dilaporkan. Anorectal myectomy dengan low anterior resection, Duhamel-Martin procedure, dan Soave endorectal pull-through procedure adalah metode yang paling dapat diterima untuk penatalaksanaan bedah. Didapatkan Kasus penyakit Hirschsprung's yang berobat di Rumah Sakit Syaiful Anwar Malang selama tahun 2008 dengan data sebagai berikut yaitu 1 orang di Januari (1 tahun) , 1 orang di Februari (6 tahun), 1 orang Maret (7 bulan), 3 orang April (7 bulan, 4 tahun dan 2 tahun), 2 orang Agustus 2008 (7 bulan dan 11 tahun). Tiap penderita mengalami riwayat abdominal distention dengan gejala perut kembung berulang, konstipasi dan kadang –kadang disertai mual. Delapan penderita yang menjalani operasi dengan prosedur endorectal pullthrough , semuanya menunjukkan hasil jangka panjang yang memuaskan.
Kata kunci: tehnik duhamel, penyakit hirschsprung's , konstipasi, infant