bluuebunny/crossref_metadata_2025_split huggingface dataset:
Allelopathic effects of leachates of Juglans regia L., Populus tremula L. and juglone on germination of temperate zone cultivated medicinal and aromatic plants
Authors: Zubay Péter , Kunzelmann Jakob , Ittzés András , Németh Zámboriné Éva , Szabó Krisztina 
Published: January 2021

AbstractThe environmental benefits of agroforestry systems are well known. However, current knowledge of potential allelopathic interactions is inadequate. The decrease in soil fertility, the increasingly rhapsodic distribution of precipitation, and the special metabolism and cultivation of medicinal and aromatic plants are all harbingers of medicinal-agroforestry systems. The authors aimed to discover the allelopathic effects ofJuglans regiaL. andPopulus tremulaL. on germination of medicinal and aromatic plants cultivated in a temperate zone. Accordingly, an in vitro germination trial was conducted with leachates of these trees and two juglone concentrations. These allelopathic effects were evaluated for germination vigour, germination rate, and total fresh weight of seedlings of twelve different species. A pronounced species specificity was observed in tolerance of seeds and seedlings to the allelopathic effect ofPopulusandJuglans. In four of the species studied, the allelopathic effect may inhibit germination, but only initially. Poppy and angelica proved to be the most sensitive to the treatments. The following species had relative tolerance to the allelochemicals, so further research under natural conditions is suggested for:Althea officinalisL. (9.34 ± 5.04–68.66 ± 13.62 GR%),Anethum graveolensL. (12.00 ± 2.00–100.00 ± 6.12 GR%),Cannabis sativaL. (72.66 ± 9.02–91.34 ± 1.16 GR%),Dracocephalum moldavicaL. (38.00 ± 2.00–80.00 ± 17.44 GR%),Linum usitatissimumL. (44.66 ± 2.00–58.00 ± 3.46 GR%), andSatureja hortensisL. (52.00 ± 28.22–82.00 ± 8.00 GR%). The aim would be to introduce them into agroforestry systems.
Improving parity games in practice
Authors: Di Stasio Antonio , Murano Aniello , Prignano Vincenzo , Sorrentino Loredana 
Published: January 2021

AbstractParity gamesare infinite-round two-player games played on directed graphs whose nodes are labeled with priorities. The winner of a play is determined by the smallest priority (even or odd) that is encountered infinitely often along the play. In the last two decades, several algorithms for solving parity games have been proposed and implemented in , a platform written in OCaml. includes theZielonka’s recursive algorithm(, for short) which is known to be the best performing one over random games. Notably, several attempts have been carried out with the aim of improving the performance of in , but with small advances in practice. In this work, we deeply revisit the implementation of by dealing with the use of specific data structures and programming languages such asScala,Java,C++, andGo. Our empirical evaluation shows that these choices are successful, gaining up to three orders of magnitude in running time over the classic version of the algorithm implemented in .
Contribution of non-native galliforms to annual variation in biomass of British birds
Authors: Blackburn Tim M. , Gaston Kevin J. 
Published: January 2021

AbstractMillions of individuals of two species of non-native galliform birds, the Common Pheasant (Phasianus colchicus) and Red-legged Partridge (Alectoris rufa) are released into the British countryside annually in late summer, supplementing established breeding populations of these two species. The biomass of birds involved in these releases has been compared to the British breeding bird biomass. However, the validity of this comparison is compromised because the biomass of wild birds varies across the year due to reproduction, mortality and migration. How the biomass of Common Pheasants and Red-legged Partridges compares to that of other British bird species in late summer, or across the whole year, is currently unknown. Here, we produce estimates of how British bird biomass varies across the year, to assess the contribution of the two non-native galliforms to this variation. We show that overall British bird biomass is probably lowest around the start of the breeding season in April, and peaks in late summer and autumn. We estimate that around a quarter of British bird biomass annually is contributed by Common Pheasants and Red-legged Partridges, and that at their peak in August these two species represent about half of all wild bird biomass in Britain.
Reducing the Nighttime Fears of Young Children Through a Brief Parent-Delivered Treatment—Effectiveness of the Hungarian Version of Uncle Lightfoot
Authors: Kopcsó Krisztina , Láng András , Coffman Mary F. 
Published: January 2021

AbstractThe aims of the present study were to evaluate the efficacy of a brief intervention, and to determine for whom the treatment works. 73 children between 3 and 8 years of age with significant nighttime fears were enrolled in an intervention group (n = 36) or in a waitlist group (n = 37). The intervention involved a 5-week parent delivered therapy. Assessments took place at baseline, post-treatment, and 20 weeks following baseline. In the intervention group, compared with the waitlist group, nighttime-related fears and phobic symptoms decreased more, whereas adaptive nighttime behavior increased to a greater extent. The more time children spent with exposure and relaxation games during the intervention, the more their separation anxiety and maladaptive nighttime behavior were reduced. Girls’ fear of darkness was reduced to a greater extent. The present study provides support for the use of parent-delivered therapy in the treatment of childhood nighttime fears.
Loss and damage from climate change and implicit assumptions of sustainable development
Authors: Boda Chad S. , Faran Turaj , Scown Murray , Dorkenoo Kelly , Chaffin Brian C. , Nastar Maryam , Boyd Emily 
Published: January 2021

AbstractLoss and damage from climate change, recognized as a unique research and policy domain through the Warsaw International Mechanism (WIM) in 2013, has drawn increasing attention among climate scientists and policy makers. Labelled by some as the “third pillar” of the international climate regime—along with mitigation and adaptation—it has been suggested that loss and damage has the potential to catalyze important synergies with other international agendas, particularly sustainable development. However, the specific approaches to sustainable development that inform loss and damage research and how these approaches influence research outcomes and policy recommendations remain largely unexplored. We offer a systematic analysis of the assumptions of sustainable development that underpins loss and damage scholarship through a comprehensive review of peer-reviewed research on loss and damage. We demonstrate that the use of specific metrics, decision criteria, and policy prescriptions by loss and damage researchers and practitioners implies an unwitting adherence to different underlying theories of sustainable development, which in turn impact how loss and damage is conceptualized and applied. In addition to research and policy implications, our review suggests that assumptions about the aims of sustainable development determine how loss and damage is conceptualized, measured, and governed, and the human development approach currently represents the most advanced perspective on sustainable development and thus loss and damage. This review supports sustainable development as a coherent, comprehensive, and integrative framework for guiding further conceptual and empirical development of loss and damage scholarship.
Single nucleotide polymorphisms in interleukin-6 attenuates hepatocytes injury in hypoxia/re-oxygenation via STAT3 signal pathway mediated autophagy
Authors: Tang Hongwei , Fang Hongbo , Guo Wenzhi , Cao Shengli , Guo Danfeng , Zhang Huapeng , Gao Jie , Zhang Shuijun 
Published: January 2021

AbstractIschemia-reperfusion injury (IRI) is inevitable during liver surgery, and it is an important factor affecting the prognosis of patients. IL-6 rs1800796 single nucleotide polymorphisms (SNPs) can promote synthesis and secretion of IL-6 and protect hepatocytes from IRI. In this study, we investigated the mechanisms by which IL-6 alleviates hepatic IRI. We transfected lentivirus which carries IL-6 rs1800796 to L02 cells and constructed the cell line (L02-IL6) with a high expression of IL-6. The biological function of IL-6 SNPs was explored through a cell model of hypoxia-reoxygenation (H/R). Cell viability was evaluated by CCK8 and Real-Time Cell Analysis (RTCA), and found that the viability of the L02-IL6 cells was higher than that of the control group (P < 0.01). Flow cytometry assay showed that the rate of apoptosis was significantly decreased in L02-IL6 cells. Furthermore, in comparison with the control group, the level of cleaved-caspase3, which is an important marker of apoptosis, was dramatically decreased. These differences showed that the sequence variants at rs1800796 of the IL-6 gene could improve the resistance against H/R. Moreover, the levels of autophagy-related proteins, such as LC3 and Beclin-1, were upregulated in L02-IL6 group on H/R injury, which means IL-6 could alleviate apoptosis via activating the autophagy pathway. And we also found that the STAT3 signal pathway was activated. Next, we investigated whether the exogenous treatment with IL-6 affect hepatocytes and thus play a protective role. We pre-treated the L02 cells with recombinant human IL-6 for 12 h and then made H/R treatment. We found the treatment with 100 ng/ml IL-6 alleviated the damage of L02 cells and inhibited the apoptosis. And the further study revealed the pre-treatment with IL-6 activated the STAT3 signaling pathway in the L02 cells and then caused the activation of autophagy and apoptosis inhibition. IL-6 might play a critical role in alleviating hepatic IRI, through its modulation of the STAT3 signaling pathway, and activation of autophagy. Recombinant human IL-6 might be a potential therapeutic target in hepatic IRI.
Discrete Harmonic Functions in the Three-Quarter Plane
Authors: Trotignon Amélie 
Published: January 2021

AbstractIn this article we are interested in finding positive discrete harmonic functions with Dirichlet conditions in three quadrants. Whereas planar lattice (random) walks in the quadrant have been well studied, the case of walks avoiding a quadrant has been developed lately. We extend the method in the quarter plane—resolution of a functional equation via boundary value problem using a conformal mapping—to the three-quarter plane applying the strategy of splitting the domain into two symmetric convex cones. We obtain a simple explicit expression for the algebraic generating function of harmonic functions associated to random walks avoiding a quadrant.
Interior Schauder Estimates for Elliptic Equations Associated with Lévy Operators
Authors: Kühn Franziska 
Published: January 2021

AbstractWe study the local regularity of solutions f to the integro-differential equation
$$ Af=g \quad \text{in } U $$

A
f
=
g

in

U

for open sets $U \subseteq \mathbb {R}^{d}$
U
⊆

ℝ

d

, where A is the infinitesimal generator of a Lévy process (Xt)t≥ 0. Under the assumption that the transition density of (Xt)t≥ 0 satisfies a certain gradient estimate, we establish interior Schauder estimates for both pointwise and weak solutions f. Our results apply for a wide class of Lévy generators, including generators of stable Lévy processes and subordinated Brownian motions.
New Model for Measuring Job Quality: Developing an European Intrinsic Job Quality Index (EIJQI)
Authors: Cascales Mira María 
Published: January 2021

AbstractThis article deals with the development of a new model for measuring job quality based on the intrinsic components of work, an European Intrinsic Job Quality Index. The objective is measure job quality on the basis of the characteristics inherent to the labour activity itself, and not from its financial rewards. First, we review the existing literature on current measurement models and justify the need for an index of this nature. Secondly, we explain the fundamental methodological decisions adopted for the construction of the index, and present the descriptive model, the indicators that make up each dimension, and the empirical model. Finally, we present the index scores by European Union countries within the framework of institutional theories. In this work, we have used a quantitative methodology, based on social indicator systems, and it has been carried out mainly with data from the European Working Conditions Survey (2015). The fundamental contribution of this article is the construction of a new model for measuring the quality of work, robust, valid and reliable, which will allow us to monitor the intrinsic job quality of the member countries, and thus provide relevant information that contributes to the framework of public policies.
How autism shows that symptoms, like psychiatric diagnoses, are 'constructed': methodological and epistemic consequences
Authors: Fellowes Sam 
Published: January 2021

AbstractCritics who are concerned over the epistemological status of psychiatric diagnoses often describe them as being constructed. In contrast, those critics usually see symptoms as relatively epistemologically unproblematic. In this paper I show that symptoms are also constructed. To do this I draw upon the demarcation between data and phenomena. I relate this distinction to psychiatry by portraying behaviour of individuals as data and symptoms as phenomena. I then draw upon philosophers who consider phenomena to be constructed to argue that symptoms are also constructed. Rather than being ready made in the world I show how symptoms are constructs we apply to the world. I highlight this with a historical example and describe methodological constraints on symptom construction. I show the epistemic problems with psychiatric diagnoses are also applicable to symptoms. Following this, I suggest that critics of psychiatric diagnoses should extend their criticism to symptoms or, if they still believe symptoms are relatively epistemologically unproblematic, should rethink their concerns over psychiatric diagnoses.
A maturity framework for autonomous solutions in manufacturing firms: The interplay of technology, ecosystem, and business model
Authors: Thomson Linus , Kamalaldin Anmar , Sjödin David , Parida Vinit 
Published: January 2021

AbstractSignificant advancements within the fields of digitalization, electrification, and automation have enabled the development, testing, and implementation of increasingly advanced autonomous solutions. Current examples of industrial automation promise significant economic and sustainability-oriented benefits for industrial customers. Yet, implemented autonomous solutions have rarely advanced beyond ‘islands of autonomy’. Although enabling initial improvements in the efficiency and effectiveness of operations, they have not led to the systemic process improvements that fully integrated site-wide solutions can achieve. It is becoming increasingly clear that the major challenges in this shift extend beyond technology to focus on business transformation and ecosystem relationships. Yet, extant research offers few insights into these domains. There is a need to develop a business-focused maturity framework for autonomous solutions to contribute to a predominantly technical discourse and support equipment actors and their wider ecosystems in commercializing autonomous solutions. Thus, the purpose of this paper is to investigate how industrial equipment manufacturers can align the development of technology, business models and ecosystem relationships for the advancement of autonomous solutions. We build on case studies that include 32 interviews from four industrial equipment manufacturers and their extended ecosystems of customers and partners. We capture our findings in a three-level maturity framework for industrial autonomous solutions. This framework unwraps the attributes of each level from the perspectives of technical system development, ecosystem configuration, and business model design and is complemented by three overarching principles for the successful commercialization of autonomous solutions.
1H, 13C and 15N chemical shift assignment of the stem-loop 5a from the 5′-UTR of SARS-CoV-2
Authors: Schnieders Robbin , Peter Stephen A. , Banijamali Elnaz , Riad Magdalena , Altincekic Nadide , Bains Jasleen Kaur , Ceylan Betül , Fürtig Boris , Grün J. Tassilo , Hengesbach Martin , Hohmann Katharina F. , Hymon Daniel , Knezic Bozana , Oxenfarth Andreas , Petzold Katja , Qureshi Nusrat S. , Richter Christian , Schlagnitweit Judith , Schlundt Andreas , Schwalbe Harald , Stirnal Elke , Sudakov Alexey , Vögele Jennifer , Wacker Anna , Weigand Julia E. , Wirmer-Bartoschek Julia , Wöhnert Jens 
Published: January 2021

AbstractThe SARS-CoV-2 (SCoV-2) virus is the causative agent of the ongoing COVID-19 pandemic. It contains a positive sense single-stranded RNA genome and belongs to the genus of Betacoronaviruses. The 5′- and 3′-genomic ends of the 30 kb SCoV-2 genome are potential antiviral drug targets. Major parts of these sequences are highly conserved among Betacoronaviruses and contain cis-acting RNA elements that affect RNA translation and replication. The 31 nucleotide (nt) long highly conserved stem-loop 5a (SL5a) is located within the 5′-untranslated region (5′-UTR) important for viral replication. SL5a features a U-rich asymmetric bulge and is capped with a 5′-UUUCGU-3′ hexaloop, which is also found in stem-loop 5b (SL5b). We herein report the extensive 1H, 13C and 15N resonance assignment of SL5a as basis for in-depth structural studies by solution NMR spectroscopy.
First successful case of percutaneous transabdominal thoracic duct embolization (PTTDE) for chylous ascites resulting from laparoscopic gastric cancer surgery
Authors: Yokokawa Hideyuki , Katsube Takao , Miyazawa Miki , Nishiguchi Ryohei , Asaka Shinichi , Yamaguchi Kentaro , Murayama Minoru , Kuhara Kotaro , Usui Takebumi , Yokomizo Hajime , Yoshimatsu Kazuhiko , Shimakawa Takeshi , Shiozawa Shunichi 
Published: January 2021

AbstractA 61-year-old woman underwent laparoscopy-assisted distal gastrectomy (LADG) with extragastric lymph node dissection (D2). Two months later, she was readmitted to hospital to be treated for chylous ascites. Oral intake was discontinued and total parenteral nutrition started, but increasing body weight and decreasing serum albumin concentration was not controllable. Percutaneous transabdominal thoracic duct embolization (PTTDE) was performed on the 8th day after the readmission. Five days after PTTDE, oral intake was resumed. Seventeen days after PTTDE, the patient was discharged without recurrence of ascites. She has remained asymptomatic. We describe here the first patient with chylous ascites two months after LADG with D2 dissection for early gastric cancer who was successfully treated by PTTDE.
Proteinuria in COVID-19: prevalence, characterization and prognostic role
Authors: Huart Justine , Bouquegneau Antoine , Lutteri Laurence , Erpicum Pauline , Grosch Stéphanie , Résimont Guillaume , Wiesen Patricia , Bovy Christophe , Krzesinski Jean-Marie , Thys Marie , Lambermont Bernard , Misset Benoît , Pottel Hans , Mariat Christophe , Cavalier Etienne , Burtey Stéphane , Jouret François , Delanaye Pierre 
Published: January 2021

Abstract
Background
Proteinuria has been commonly reported in patients with COVID-19. However, only dipstick tests have been frequently used thus far. Here, the quantification and characterization of proteinuria were investigated and their association with mortality was assessed.

Methods
This retrospective, observational, single center study included 153 patients, hospitalized with COVID-19 between March 28th and April 30th, 2020, in whom total proteinuria and urinary α1-microglobulin (a marker of tubular injury) were measured. Association with mortality was evaluated, with a follow-up until May 7th, 2020.

Results
According to the Kidney Disease Improving Global Outcomes staging, 14% (n = 21) of the patients had category 1 proteinuria (< 150 mg/g of urine creatinine), 42% (n = 64) had category 2 (between 150 and 500 mg/g) and 44% (n = 68) had category 3 proteinuria (over 500 mg/g). Urine α1-microglobulin concentration was higher than 15 mg/g in 89% of patients. After a median follow-up of 27 [14;30] days, the mortality rate reached 18%. Total proteinuria and urinary α1-microglobulin were associated with mortality in unadjusted and adjusted models. This association was stronger in subgroups of patients with normal renal function and without a urinary catheter.

Conclusions
Proteinuria is frequent in patients with COVID-19. Its characterization suggests a tubular origin, with increased urinary α1-microglobulin. Tubular proteinuria was associated with mortality in COVID-19 in our restropective, observational study.
Investigation on physicochemical properties of graphene oxide/nano-hydroxyapatite composites and its biomedical applications
Authors: Yang Zebin , Liu Jitao , Liu Jinkun , Chen Xiliang , Yan Tingting , Chen Qinghua 
Published: January 2021

AbstractGraphene oxide/nano-hydroxyapatite (GO/nHAP) composites were synthesized by simultaneous titration method. The GO powder was uniformly dispersed ultrasonically in a solution containing Ca(NO3)2. It was co-titrated with (NH4)2HPO4, during which NH3·H2O was used to maintain pH of about 10. Transmission electron microscopy (TEM) showed that HAP had a drusy acicular crystal structure with 100–200 nm length in the composite. The Ca2+ ions were attracted by the negatively charged oxygen functional groups present on GO sheets. They also oriented the growth of hydroxyapatite preferentially along (112) plane, which was also consistent with X-ray diffractometry (XRD) results. According to X-ray photoelectron spectroscopic (XPS) results, the peak intensities of the C–O and C–C groups increased in the GO/nHAP composite. However, the number of –COO– and C–O–C groups was reduced as well as the position of peaks shifted due to electrostatic interactions. These results were also corroborated with Fourier transform infrared spectroscopy (FTIR). MTT assay indicated that GO/nHAP composites had a significant effect on proliferation of 293T cells and good biomimetic mineralization as shown by in vitro bioactivity assays. EDS spectroscopy confirmed that the Ca/P ratio in calcium phosphate deposits was 1.62, which was close to the ratio of 1.64 in natural bone. The biological performance of GO/nHAP composite proved it to be a promising candidate for bone regeneration and implantation.
Total- and semi-bare noble metal nanoparticles@silica core@shell catalysts for hydrogen generation by formic acid decomposition
Authors: Santucci Marco , Ermini Maria Laura , Bresciani Giulio , Griesi Andrea , Gemmi Mauro , Pampaloni Guido , Marchetti Fabio , Voliani Valerio 
Published: January 2021

AbstractCatalysts are involved in a number of established and emerging chemical processes as well as in environmental remediation and energy conversion. Nanoparticles (NPs) can offer several advantages over some conventional catalysts, such as higher efficiency and selectivity. Nowadays, versatile and scalable nanocatalysts that combine activity and stability are still lacking. Here, we report a comprehensive investigation on the production and characterization of hybrid nano-architectures bringing a partial or total bare surface together with their catalytic efficiency evaluation on, as a proof-of-concept, the formic acid decomposition reaction. In this regard, formic acid (FA) is a convenient and safe hydrogen carrier with appealing features for mobile applications, fuel cells technologies, petrochemical processes and energetic applications. Thus, the design of robust catalysts for FA dehydrogenation is strongly demanded. Due to this, we produced and evaluated nano-architectures with various equilibrium between the size-increase of the active part and the barer catalytic surface. Overall, this work paves the way for the development of new approaches for green energy storage and safe delivery.