bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short- and long-term warming effects of methane may affect the cost-effectiveness of mitigation policies and benefits of low-meat diets
Authors: Pérez-Domínguez Ignacio , del Prado Agustin , Mittenzwei Klaus , Hristov Jordan , Frank Stefan , Tabeau Andrzej , Witzke Peter , Havlik Petr , van Meijl Hans , Lynch John , Stehfest Elke , Pardo Guillermo , Barreiro-Hurle Jesus , Koopman Jason F. L. , Sanz-Sánchez María José 
Published: December 2021

AbstractMethane’s short atmospheric life has important implications for the design of global climate change mitigation policies in agriculture. Three different agricultural economic models are used to explore how short- and long-term warming effects of methane can affect the cost-effectiveness of mitigation policies and dietary transitions. Results show that the choice of a particular metric for methane’s warming potential is key to determine optimal mitigation options, with metrics based on shorter-term impacts leading to greater overall emission reduction. Also, the promotion of low-meat diets is more effective at reducing greenhouse gas emissions compared to carbon pricing when mitigation policies are based on metrics that reflect methane’s long-term behaviour. A combination of stringent mitigation measures and dietary changes could achieve substantial emission reduction levels, helping reverse the contribution of agriculture to global warming.
PINK1 signalling in neurodegenerative disease
Authors: Whiten Daniel R. , Cox Dezerae , Sue Carolyn M. 
Published: December 2021

Abstract
PTEN-induced kinase 1 (PINK1) impacts cell health and human pathology through diverse pathways. The strict processing of full-length PINK1 on the outer mitochondrial membrane populates a cytoplasmic pool of cleaved PINK1 (cPINK1) that is constitutively degraded. However, despite rapid proteasomal clearance, cPINK1 still appears to exert quality control influence over the neuronal protein homeostasis network, including protein synthesis and degradation machineries. The cytoplasmic concentration and activity of this molecule is therefore a powerful sensor that coordinates aspects of mitochondrial and cellular health. In addition, full-length PINK1 is retained on the mitochondrial membrane following depolarisation, where it is a powerful inducer of multiple mitophagic pathways. This function is executed primarily through the phosphorylation of several ubiquitin ligases, including its most widely studied substrate Parkin. Furthermore, the phosphorylation of both pro- and anti-apoptotic proteins by mitochondrial PINK1 acts as a pro-cellular survival signal when faced with apoptotic stimuli. Through these varied roles PINK1 directly influences functions central to cell dysfunction in neurodegenerative disease.
AMIC Technique for the Treatment of Chondral Injuries of the Hand and Wrist
Authors: de Vega Pau López-Osornio , Bauxauli Vicente Carratalà , Corella Fernando , Andrade Cristóbal Martínez 
Published: December 2021

AbstractScaffolds, either alone or combined with cultured chondrocyte cells, are an effective treatment for chondral or osteochondral defects of the knee and ankle joints.Scaffolds are a more sophisticated solution and have some advantages compared with the isolated use of the more traditional treatments of microfractures or nanofractures.In addition, scaffolds represent a less complicated technique and a less expensive treatment compared with chondrocyte culture treatments, which are accessible by very few patients.In the present article, we detail the surgical technique and provide advices and tips for the treatment of ostecochondral hand and wrist lesions using the Chondro-Gide (Geistlich Pharma AG, Wolhausen, Switzerland) scaffold and its patented autologous matrix-induced chondrogenesis (AMIC, Geistlich Pharma AG) technique.
Four-Corner Fusion with Locking Dorsal Circular Plate versus Headless Compression Screws: A Clinico-Radiological Comparative Study
Authors: Melibosky Francisco R. , Jorquera Rene A. , Saxton Felipe Z. , Orellana Pablo , Junqueras Diego , Azócar Camila 
Published: December 2021

AbstractIntroduction Four-corner fusion is a technique for the treatment of carpal advanced collapse. It consists of scaphoid excision and arthrodesis of the lunate, triquetrum, hamate, and capitate bones. This can be accomplished with different kinds of osteosynthesis. In the first reports of the use of a circular plate, poor outcomes are described, with high rates of non-union, which decreased in later studies, which highlight certain aspects of the surgical technique.Objective To report our experience with four-corner fusion with the use of a dorsal locking plate (Xpode, Trimed Inc., Santa Clarita, CA, US), and compare it with another traditional fixation method (3.0-mm headless compression screws [HCSs], Synthes, Slothurn, Switzerland), with an emphasis on union, an assessment of the fincitonal outcomes, and the presence of complications.Material and Methods A comparative study of two prospective series of patients operated on through two fixation techniques for four-corner fusion using autologous bone graft from the iliac crest.The first group of patients, evaluated between 2010 and 2012, underwent osteosynthesis with 2 HCSs, with a minimum follow up of 18 months. The second group, evaluated between 2011 and 2014, underwent osteosynthesis with a dorsal locking plate, with a minimium foloow up of 12 months. The patients were operated on by four different surgeons in four centers.The patients were evaluated with radiographs to establish the presence of union and the time it took to occur. In case of doubt, union was confirmed through a computed tomography (CT) scan at 8 weeks postoperatrively. We also assessed the range of motion, the presence of complications, and function through the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire and a grip strength score.Results We achieved a union rate of 100% in both groups at similar times. In the dorsal locking plate group, we obtained better full range of motion, particularly in wrist extension, which was statistically significant (p = 0.0016), as well as lower DASH scores, which was also statistically significant (p = 0.0066). Complications were only present in two patients in the HCS group.Conclusion Both techniques are valid and reproducible for the treatment of wrists with scapholunate advanced collapse (SNAC) and scaphoid non-union advanced collapse (SLAC). Based on the outcomes, with the Xpode plate, the patients presented better ranges of motion and DASH scores; therefore it may be an excellent fixation option in the open four-corner fusion surgical technique. The entry point and configuration of the HCS are fundamental variables to analyze.The union rate of 100% obtained in the present study contrasts with the high rates of non-union reported in the literature published in the early 2000s.
Madelung Deformity: Diagnosis and Treatment Options
Authors: Oliveira Ricardo Kaempf de , Ribak Samuel , Brunelli João Pedro Farina , Aita Márcio , Delgado Pedro J. 
Published: December 2021

AbstractMadelung deformity (MD) comprises an increased volar and ulnar tilt of the joint facet of the distal radius, secondary to an idiopathic physeal dysplasia. Such change causes radial shortening and consequent distal ulnar prominence, along with wrist pain and loss of motion. Surgery becomes an option in patients with severe deformity that do not respond to conservative treatment.The classic surgical techniques are problematic for adults, as they are specific for children and adolescents, whose radial physis is still open. Very few papers discuss the treatment of adult patients; furthermore, most are focused on the distal radioulnar joint, and thus do not approach the origin of the pathology.When analyzing computed tomography scans with tridimensional reconstruction, a feature of MD, growth arrest of the volar and ulnar portions of the distal radius, is noted, causing the typical distal radius deformity that leads to lack of coverage of the lunate bone. That leads to palmar subluxation of the lunate bone and consequent radiocarpal instability.We herein describe the possibilities of treatment in different stages of evolution, summarizing the authors' view on MD.
Multiplexed sensing of biomolecules with optically detected magnetic resonance of nitrogen-vacancy centers in diamond
Authors: Kayci Metin , Fan Jilin , Bakirman Onur , Herrmann Andreas 
Published: December 2021

Significance
Bioassay applications that use magnetic nanotags to convert specific molecular interactions into a detectable magnetic dipole represent a rapidly advancing field of nanotechnology to develop next-generation diagnostics while providing the capability for simultaneous noninvasive manipulation in an external magnetic field. Although absorption, autofluorescence, scattering, photobleaching, blinking, and chemical quenching are major noise components for fluorescent markers in thick and opaque heterogeneous biological samples, they are not the significant limiting factors for the magnetic detection systems using magnetic nanotags. Here, we report progress toward a multiplexed magneto-DNA assay platform with position-indexed hydrogel microstructures decorated for sequence-specific nucleic acid detection and a complementary magnetic-imaging system using nitrogen-vacancy quantum centers in diamond.
Body and mind? Exploring physiological and psychological factors to explain endurance performance in cycling
Authors: Röthlin Philipp , Wyler Marco , Müller Beat , Zenger Nina , Kellenberger Katja , Wehrlin Jon Peter , Birrer Daniel , Lorenzetti Silvio , Trösch Severin 
Published: December 2021

ABSTRACTEndurance athletes attribute performance not only to physiological factors, but also refer to psychological factors such as motivation. The goal of this study was to quantify the proportion of the variance in endurance performance that is explained by psychological factors in addition to the physiological factor VO2max. Twenty‐five athletes of the U17 Swiss Cycling national team (7f, 18 m, 15.3 ± 0.5 years) were examined in a cross‐sectional study with psychological factors and VO2max as independent variables and endurance performance in road cycling as dependent variable. Questionnaires were used to assess psychological factors (i.e. use of mental techniques, self‐compassion, mental toughness, achievement motivation, and action vs. state orientation). VO2max was measured by a step incremental cycle ergometer test of exhaustion. Endurance performance was measured in a cycling mountain time trial (1,320 m long, incline of 546 meters). A multiple regression model was created by using forward selection of regression model predictors. Results showed that higher VO2max values (β = .48), being male (β = .26), and higher achievement motivation (i.e. perseverance, β = .11) were associated with a better endurance performance. A more frequent use of one particular mental technique (i.e. relaxation techniques, β = .03) was associated with a worse endurance performance. Our study shows that a physiological factor like VO2max explains endurance performance to a large extent but psychological factors account for additional variance. In particular, one aspect of achievement motivation, namely perseverance, was associated with a better endurance performance.

HIGHLIGHTS
Endurance performance is explained by physiological (e.g. VO2max) and psychological (e.g. perseverance) factors
VO2max explains young cyclists’ endurance performance to a large extent
Perseverance explained performance beyond the influence of VO2max
Key comparison BIPM.RI(I)-K4 of the absorbed dose to water standards of the NRC, Canada and the BIPM in 60Co gamma radiation
Authors: Kessler C , Burns D , Downton B , McEwen M 
Published: December 2021

Main text
A new key comparison of the standards for absorbed dose to water of the National Research Council of Canada (NRC), Canada and the Bureau International des Poids et Mesures (BIPM) was carried out in the 60Co radiation beam of the BIPM in October 2020. The comparison result, based on the calibration coefficients for three transfer standards and evaluated as a ratio of the NRC and the BIPM standards for absorbed dose to water, is 0.9995 with a combined standard uncertainty of 3.4 parts in 103. The result agrees within the uncertainties with the comparison carried out in 2009. The results are analysed and presented in terms of degrees of equivalence, suitable for entry in the BIPM key comparison database.
To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/.
The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Insights into the surface responses of graphene oxide irradiated by an infrared femtosecond laser
Authors: Ding Ye , Li Qiang , Li Jingyi , Wang Lianfu , Yang Lijun 
Published: December 2021

Abstract
Graphene oxide (GO) has emerged as a unique and multifaceted novel material with a wide range of applications in electrochemistry and optoelectronic engineering. In these applications, the GO surface is characterized with different functional structures in the micro-nano scale, while the femtosecond laser is a promising and versatile tool for manufacturing these structures comparing with conventional approaches. However, the comprehensive surface responses and corresponding regimes of GO surface under femtosecond laser irradiation are not yet identified, which creates obstacles to the further application of femtosecond lasers in programming GO surfaces with specific nanopatterns. Herein, theoretical models characterizing the electrical response, i.e. the transient spatial and temporal distribution of infrared femtosecond laser-excited free electron density at the GO surface layers are established. The numerical simulations are carried out using the discontinuous Galerkin finite element algorithm with a 5 fs time step. The relationship between the laser polarized electric field and free electron density is revealed. On this basis, the surface plasma distribution is characterized, the accuracy of which is verified through the comparison of experimental ablation morphology. Thermal, morphological and chemical responses of the GO surface using different parameters are analyzed correspondingly, from which the formation and evolution mechanisms of surface nanopatterns with different features are explained. This work offers a new insight into the fundamental regimes and feasibility of ultrafast patterning of GO for the application of multifunctional device engineering.
Color Changes and Resistance Against Subterranean Termites Attack of Furfuryl Alcohol Impregnated Pine and Sengon Woods Through Graveyard Test
Authors: Sabrina P A , Hadi Y S , Nawawi D S , Abdillah I B , Pari R 
Published: December 2021

AbstractPine (Pinus merkusiiJungh. & de Vriese) and sengon (Falcataria moluccana(Miq.) Barneby & J.W. Grimes) are common species of woods used for many purposes. Both species are known susceptible against subterranean termite attack. This study aims to analyze the effect of furfuryl alcohol impregnation on color changes and the resistance against subterranean termites of pinewood and sengon after in-ground test for one year. Furfurylated pine and sengon woods reached weight percent gain 31.2% and 79.1%, densities 0.93 g/cm3and 0.43 g/cm3, moisture content 3.27% and 2.88%, respectively. Furfurylated pine and sengon woods have lost weight 4.07% dan 2.09%, respectively, with the average resistance level of 9.8 on both woods while untreated pine and sengon woods lost weight were 59.02% and 35.58%, with resistance level 4 and 3.8, respectively. Resistance level scoring was conducted by refering to ASTM D1758-06. Higher resistance level and lower weight loss on both furfurylated woods compared to untreated woods showed that furfurylation could increase the wood resistance against termite attack.
Polyphenol contents and free radical scavenging activity of Pinus merkusii cone
Authors: Masendra  , Ngadianto A , Arifriana R , Maulidia F , Minorita W , Purba B A V , Lukmandaru G 
Published: December 2021

AbstractThis study aimed to investigate the polyphenol contents from thePinus merkusiicone extract and their antioxidant activity. The cone powder (40 mesh) was extracted withn-hexane, ethyl acetate, and methanol successively for six hours. The cone ofn-hexane, ethyl acetate, and methanol soluble extracts was subjected to total tannin content, total phenol content, total flavonoid content, and antioxidant measurements. The polyphenol contents were measured through the colorimetric method, while antioxidant activity was observed by inhibition of the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The results showed that total tannin content, total phenol content, total flavonoid content, and antioxidant activity of methanol soluble extract was higher than ethyl acetate andn-hexane soluble extracts. In this study, the high antioxidant activity of methanol soluble extract (IC50of 196.73±13.93 ppm) might due to the high concentration of total phenol content (545.38±54.07 mg GAE/g sample). It was suggested that theP. merkusiicone is potential as the antioxidant source.
Characteristics of impregnated wood by nano silica from betung bamboo leaves
Authors: Rahayu I , Pratama A , Darmawan W , Nandika D , Prihatini E 
Published: December 2021

Abstract
Abstract, Sengon (Falcataria moluccana Miq.) as a fast-growing wood species that has low quality. Therefore, wood modification is needed to improve its wood qualities. The objective of this study was to analyse the effect of monoethylene glycol (MEG) and nano silica of betung bamboo leaves impregnation treatment on physical, mechanical properties and durability of sengon wood. 5-years-old Sengon wood from community forest, MEG and nano silica (average size = 436.16 nm) from betung bamboo leaves were used. The impregnation solutions were consisted of water treated (untreated), MEG, MEGSilika 0.5% and MEGSilika 1%. Impregnation process with 0.5 bar (60 minutes) vacuum and 2.5 bar (120 minutes) pressure. Physical properties (density and colour alteration), mechanical properties (Modulus of Elasticity (MOE), Modulus of Rupture (MOR) and hardness) and durability against subterranean (Coptotermes curvignathus) attack. The results showed that the weight percent gain (WPG) and density of treated Sengon wood were increased as the nano silica concentration increased. While colour alteration (Δε) of treated samples were declining. Mechanical properties (MOE, MOR and hardness) were also improved. Durability based on laboratory tested against subterranean attack resulted that the percentage of termite mortality from the treated samples increased, while the percentage of weight loss decreased.
The first results of the seismic monitoring system of the Solntsevsky open pit coal mine area (on Sakhalin Island)
Authors: Kostylev D V , Boginskaya N V 
Published: December 2021

Abstract
In 2021, work began as a part of the implementation of the decision of the protocol of the Sakhalin branch of the Russian Expert Council on earthquake prediction, seismic hazard and risk assessment dated October 6, 2020 on detailed monitoring in the area of active coal mining at the Solntsevsky open pit coal mine (Sakhalin Island). New points of seismic monitoring were installed directly in the area of the open pit coal mine. Integration of real-time data received from the points in real time into a unified seismic monitoring system in the Sakhalin Region was ensured. The results of registration of seismic events of various origins since the commissioning of the stations are presented. A significant increase in the accuracy of the determined epicenters and the possibilities of determining earthquakes and industrial explosions has been noted. The results of the monitoring system for studying the landslide process in the area of the open pit coal mine, as well as the probable factors that caused the landslide, are shown. The developed monitoring system allows for representative registration of seismic events with ML ≥ 0.8 in the immediate vicinity of open pit coal mine, which makes it possible to control blasting operations with increased accuracy, as well as weak and possible induced seismicity formed as a result of a constant technogenic impact on the subsoil.
Study of the tectonic structure and modern geodynamics of the nickel-copper-sulfide Kun-Manyo deposit at the stage of its field the development
Authors: Potapchuk M I , Rasskazov I Yu , Usikov V I , Kryukov V G 
Published: December 2021

Abstract
Currently, the Kun-Manyo nickel-copper-sulfide deposit in the north of the Khabarovsk Krai is being prepared for development, with part of the reserves expected to be mined by underground mining. To justify the rational order of opening and excavation of sub-ore reserves it is necessary to have objective information on rock mass condition, which can be received as a result of complex geodynamic and geomechanical investigations.
The established geodynamic position of the deposit, determined by its location at the junction of actively interacting large tectonic elements of the Euro-Asian tectonic plate – the tectonic stress of the North Asian craton and the Amur plate, as well as within the modern Olekmo-Stanovo seismic zone, has allowed the massif of the field area to be classified as tectonically stressed.
An analysis of the data of the GPS-observation points on the territory of the Russian part of the Amur tectonic plate, the results of calculations of the vector field of velocities of modern movements of points, made within the framework of the ITRF – 2000 coordinate system, as well as the results of in-situ geomechanical studies of rock massifs of the Amur Plate’s rock-bump hazardous deposits, have made it possible to establish the current tectonic regime of the deposit area – a region of intense modern compression with a predicted intensity of more than 50 MPa. By methods of morphometric analysis and remote sensing, it has been found that the relative relief excesses were significant (700–1000 m), which may lead to an uncompensated horizontal component of geostatic stress. The most extended lineaments of the relief have predominantly southeasterly extension. The identified features of the tectonic structure and regional neotectonics have made it possible to determine the most probable direction and magnitude of the current main horizontal compression, which could be further used in solving various geomechanical problems in the exploitation of the field.
Development of the dual-channel frequency meter for measurements with hydrostatic pressure sensor
Authors: Stovbun N S , Gulyakov S A 
Published: December 2021

Abstract
The paper describes the process and the results of development of the dual-channel frequency meter, which function is to measure the output frequency generated by bottom-mounted pressure sensors. The sensors are actively used to monitor the marine environment. AVR family microcontrollers were used as the computing core of the presented device. This solution allows to obtain far lower power consumption, which is especially important when operating with no industrial power supply system in the coastal zone. As a result, we can deploy a reliable monitoring equipment capable of long-term saving data and if necessary transmit it for further processing. The developed frequency-meter is able to continually record the ambient temperature, atmospheric pressure and dynamically varying output frequency, which depends on hydrostatic pressure (sea level). To obtain more accurate data, we implemented a frequency measure method called reciprocal counter with lower relative error not affected by value of the output frequency. A laboratory experiment has been conducted, which confirms the suitability of the developed frequency meter for field-oriented conditions.