bluuebunny/crossref_metadata_2025_split huggingface dataset:
Platelet Indices as Potential Monitoring Biomarkers in COVID-19: A New Hope
Authors: Khalid Attika , Saeed Sami , Rehan Madeeha , Arif Nadia 
Published: April 2021

Objective: To investigate the relationship between established acute inflammatory markers in COVID-19 patients with Mean platelet volume (MPV) and Platelet large cell ratio (P-LCR).
Materials and Methods: This was a retrospective longitudinal study conducted at Fauji Foundation Hospital, Rawalpindi from 10th June to 10th August 2020. Biochemical parameters i.e. CRP, serum ferritin, LDH, and pro-BNP as well as hematological parameters (MPV and P-LCR) were noted once every week during admission of all the COVID-19 positive patients.Data were analyzed using IBM-SPSS version 23. Repeated measure ANOVA using a generalized linear model was done to check the trend of values during the duration of their stay. Pearson Correlation analysis and regression models were estimated to check the relationship of MPV and P-LCR with C- reactive protein, serum Ferritin, LDH, and pro-BNP. P-values less than 0.05 were considered statistically significant.
Results: The mean age of the studied group was 55.47 (SD=±15.0) years with the female to male ratio being 2:1. Mean platelet volume showed a statistically significant positive correlation with the established set of inflammatory markers other than pro-BNP with a p-value of less than 0.05.P-LCR however showed a positive correlation with CRP (p-value of less than 0.05) only with no significant correlation with other biochemical markers.
Conclusion: MPV is reported on routine complete blood count report (CBC). It is readily available at even the most under-resourced health centers; therefore reporting the platelet indices does not require extra testing, sampling, or reagent cost. A statistically significant positive correlation amongst the established acute inflammatory markers and relatively understudied platelet indices (MPV) in COVID-19 provides a cost-effective, readily available, and time-efficient tool for marking disease progression.
Connection between Galaxies and H i in Circumgalactic and Intergalactic Media: Variation according to Galaxy Stellar Mass and Star Formation Activity
Authors: Momose Rieko , Shimizu Ikkoh , Nagamine Kentaro , Shimasaku Kazuhiro , Kashikawa Nobunari , Kusakabe Haruka 
Published: April 2021

Abstract
This paper systematically investigates the comoving megaparsec-scale intergalactic medium (IGM) environment around galaxies traced by the Lyα forest. Using our cosmological hydrodynamic simulations, we investigate the IGM–galaxy connection at z = 2 by two methods: (i) cross-correlation analysis between galaxies and the fluctuation of Lyα forest transmission (δ
F) and (ii) comparison of the overdensity of neutral hydrogen (H i) and galaxies. Our simulations reproduce observed cross-correlation functions (CCFs) between Lyα forest and Lyman-break galaxies. We further investigate the variation of the CCF using subsamples divided by dark matter halo mass (M
DH), galaxy stellar mass (M
⋆), and star formation rate (SFR) and find that the CCF signal becomes stronger with increasing M
DH, M
⋆, and SFR. The CCFs between galaxies and gas density fluctuation are also found to have similar trends. Therefore, the variation of δ
F–CCF depending on M
DH, M
⋆, and SFR is due to varying gas densities around galaxies. We find that the correlation between galaxies and the IGM H i distribution strongly depends on M
DH as expected from linear theory. Our results support the ΛCDM paradigm, confirming a spatial correlation between galaxies and IGM H i, with more massive galaxies being clustered in higher-density regions.
Revealing a New Black Widow Binary 4FGL J0336.0+7502
Authors: Li Kwan-Lok , Jane Yap Y. X. , Hui Chung Yue , Kong Albert K. H. 
Published: April 2021

Abstract
We report on the discovery of a promising candidate for a black widow (BW) millisecond pulsar binary, 4FGL J0336.0+7502, which shows many pulsar-like properties in the 4FGL-DR2 catalog. Within the 95% error region of the LAT source, we identified an optical counterpart with a clear periodicity at P
orb = 3.718178(9) hr using the Bohyunsan 1.8 m Telescope, the Lulin One-meter Telescope, the Canada–France–Hawaii Telescope, and Gemini-North. At the optical position, an X-ray source was marginally detected in the Swift/X-Ray Telescope archival data, and the detection was confirmed by our Chandra/ACIS DDT observation. The spectrum of the X-ray source can be described by a power-law model of Γ
x
= 1.6 ± 0.7 and

erg cm−2 s−1. The X-ray photon index and the low X-ray-to-γ-ray flux ratio (i.e., <1%) are both consistent with that of many known BW pulsars. There is also a hint of an X-ray orbital modulation in the Chandra data, although the significance is very low (1.3σ). If the pulsar identity and the X-ray modulation are confirmed, it would be the fifth BW millisecond pulsar binary that showed an orbitally modulated emission in X-rays.
Assessing the Stellar Population and the Environment of an H ii Region on the Far Side of the Galaxy*
Authors: Chené André-Nicolas ,   (VVV Survey), Benjamin Robert A. ,   (Glimpse Survey), Ramírez-Alegría Sebastian , Borissova Jura , Kurtev Radostin , Bidin Christian Moni , Mauro Francesco , Lucas Phil , Guo Zhen , Smith Leigh C. , Gonzalez-Fernandez Carlos , Ivanov Valentin D. , Minniti Dante ,   (VVV Survey), Anderson Loren. D. , Armentrout William. P. , Gonzalez Danilo , Herrero Artemio , Ramírez Karla Peña 
Published: April 2021

Abstract
We have investigated the stellar and interstellar content of the distant star formation region IRAS 17591-2228 (WISE H ii region GAL 007.47+0.06). It is associated with a water maser, whose parallax distance is

kpc, supported by independent measurements of proper motion and radial velocity. It is projected in the same direction as an extremely red (J−K

S
∼ 6 mag) group of stars, and a shell of mid-infrared emission. We qualify the group of stars as a cluster candidate, VVV CL177. Its radius spans between 0.′45 and 1′ and contains at least two young stellar objects with an extreme extinction near

mag. Yet more analysis will be required to determine if it is a real single cluster associated with the water maser. The 13CO emissions at the radial velocity of the maser corresponds to the mid-infrared emission.
Nonlinear Ion-acoustic Waves, Ion Holes, and Electron Holes in the Near-Sun Solar Wind
Authors: Mozer F. S. , Bonnell J. W. , Hanson E. L. M. , Gasque L. C. , Vasko I. Y. 
Published: April 2021

Abstract
Nonlinear ion-acoustic waves, ion holes, and electron holes have been observed on the Parker Solar Probe at a heliocentric distance of 35 solar radii. These time domain structures contain millisecond duration electric field spikes of several mV m−1. They are observed inside or at boundaries of switchbacks in the background magnetic field. Their presence in switchbacks indicates that both electron- and ion-streaming electrostatic instabilities occur there to thermalize electron and ion beams.
Construction of metronidazole capped in gold nanoparticles against Helicobacter pylori: antimicrobial activity improvement
Authors: Fateh Roohollah , Javadi Ali , Kardan-Yamch Jalil , Ali Rahdar Hossein , Amini Masumeh , Ghasemi Fatemeh , Azimi Akram , Davarpanah Masoumeh , Mohammadzadeh Razieh 
Published: April 2021

Introduction:Helicobacter pylori is considered a major agent causing gastritis and peptic ulcer disease. Unfortunately, the occurrence of increasing drug resistance to this bacterium would result in some difficulties in its treatment. Therefore, the application of nanotechnology has been suggested to resolve such problems. Nanoparticles usage in medical research has been expanded in recent years. Among nanometals, gold nanoparticles have exclusive features that can be used in such applications. Using nanotechnology in medical science could help mankind to solve this problem in the future.
Aim: Our aim in this research was to investigate the antimicrobial effect of gold nanoparticles on H. pylori strains.
Materials and methods: Gold nanoparticles were synthesized by the Turkevich method. Then, their size and dispersion were investigated using spectrophotometry, DLS, and TEM microscopy. Subsequently, the combination of metronidazole and gold nanoparticles was obtained by mixing method, and then the anti-helicobacter effects of the two were evaluated according to CLSI.
Results: The highest size of gold nanoparticles was between 12 and 9 nm, and the maximum absorbance was 522 nm; however, in conjugated state, the maximum absorbance was 540 nm, which indicated the accumulation of drug-conjugated nanoparticles in the conjugate state. Some changes indicated the binding of metronidazole to gold nanoparticles. Antimicrobial testing of gold nanoparticles and metronidazole did not affect the Helicobacter pylori. Therefore, the combination of gold nanoparticles and metronidazole had a 17-mm growth inhibition zone.
Conclusions: The anti-helicobacter effects of metronidazole significantly increased in conjugation with gold nanoparticles.
Dental fear and anxiety in children: a review of the environmental factors
Authors: Shindova Maria P. , Belcheva Ani B. 
Published: April 2021

Dental fear and anxiety are psychological reactions that interfere significantly with daily life. They are problems suffered by many patients worldwide that remain a significant challenge to providing adequate dental care. The multifactorial etiology of children&rsquo;s dental fear and anxiety identifies the influence of many different risk factors in its development.
The aim of this review article is to analyse the scientific literature regarding the different factors associated with dental fear and anxiety in children. Our review of the literature presents a critical analysis of the contributing factors in dental environment that have been investigated in the literature and provides an insight into the possible explanations on the influence of these factors in pediatric patients.
Being familiar with these factors would facilitate behaviour management in anxious children. The findings of the literature review give grounds to undertake studies investigating the influence of contributing factors in all pediatric age subgroups.
Evaluation of serum vitamin D levels in COVID-19 positive critically ill adults
Authors: Alsegai Ola , Sridharan Kannan , Hammad Mona , Hammad Mustafa Mohamed 
Published: April 2021

Background: Contradictory evidence exists regarding the association between serum vitamin D levels and the severity and outcomes in coronavirus 2019 (COVID-19) infected patients. We undertook the present study to evaluate the serum vitamin D levels with the other laboratory biomarkers, and the outcomes in our critically ill patients.
Methods: A retrospective observational study was carried out in 58 critically ill adults. Details on their demographics, laboratory parameters such as 25-hydroxy vitamin D [25(OH)D] levels, interleukin-6, serum ferritin, lactate dehydrogenase, creatine kinase (CK), D-dimer, C-reactive protein, fibrinogen, procalcitonin, and erythrocyte sedimentation rate were retrieved. Serum 25(OH)D levels were categorized as follows: ≥50 nmol/L – normal; 30–49 – insufficient; and &lt;30 nmol/L – deficient. Post-hoc, we also compared the outcomes between those with 25(OH)D levels of 80 nmol/L and above, with those of &lt;80 nmol/L.
Results: Fifty-eight patients were recruited of which 31 (53.4%) died. Mean ± SD serum 25(OH)D levels amongst the study participants were 48.5 ± 27.7 nmol/L. Twenty-two (37.9%) individuals had insufficient 25(OH)D levels, and 15 (25.9%) were deficient. Eight (13.8%) participants had their serum 25(OH)D levels ≥80 nmol/L. Median (range) 25(OH)D levels were not significantly different between those who died compared to those alive [41 (20–162) vs. 41 (17–86) nmol/L; p = 0.8]. Significantly higher D-dimer levels were observed amongst those with &lt;80 nmol/L serum 25(OH)D levels. No significant differences were observed between 25(OH)D and other laboratory biomarkers except for elevated CK in patients with insufficient 25(OH)D levels.
Conclusion: We did not observe any significant differences in the serum 25(OH)D levels amongst our critically ill adults who died and who were alive at the time of their admission.
« Les faits sont toujours des amis »
Authors: Behr Michael , Zeller Odile , Brison Céline 
Published: April 2021

Tant les recherches singulières que les méta-analyses établissent que les grands courants en psychothérapie bénéficient tous d’une efficacité similaire. La psychothérapie centrée sur la personne et expérientielle obtient en particulier d’aussi bons résultats que la thérapie cognitivo-comportementale, surtout lorsque les recherches prennent en compte l’appartenance des chercheurs à une orientation particulière. De nombreuses recherches portant sur les thérapies avec des enfants ou des adolescents le démontrent également. Le travail thérapeutique centré sur la personne et expérientiel obtient même des résultats encore un peu meilleurs en comparaison avec la thérapie centrée sur la personne « classique ». Les recherches qualitatives confirment la théorie centrée sur la personne des processus des clients et relativisent le regard se portant exclusivement sur les symptômes. De même, il existe tellement de recherches spécifiques sur l’efficacité de l’Approche centrée sur la personne en fonction des troubles que les méta-analyses tenant compte de ces recherches singulières peuvent donner des mesures d’efficacité spécifiques en fonction des troubles. Dans des champs d’application voisins tels que la thérapie filiale (entre parents et enfants ou adolescents), l’entretien motivationnel, la méthode Gordon et dans tout le domaine scolaire et éducatif, les méta-analyses prouvent également l’efficacité significative de l’Approche centrée sur la personne. La recherche empirique en psychothérapie est associée historiquement à Rogers et à l’Approche centrée sur la personne. Sa formule « Les faits sont toujours des amis » le révèle comme un chercheur d’une rare exigence. La plupart des chercheurs cognitivo-comportementaux voient d’ailleurs la thérapie centrée sur la personne et expérientielle d’un bon œil. Les limitations de la méthode méta-analytique, en particulier dans le choix des recherches incluses, mènent, dans certains cas isolés, à des artefacts non fondés méthodologiquement, selon lesquels une méthode l’emporterait sur les autres.
Ce que peut la littérature. Lire Charlotte Delbo
Authors: Dunant Ghislaine 
Published: April 2021

Je montre comment une œuvre littéraire a pu raccommoder le trou qu’a fait dans mon humanité la catastrophe d’Auschwitz. Charlotte Delbo fait voir les scènes vécues à Birkenau avec une écriture lucide jusqu’à l’épouvante et un regard d’empathie. Sa langue sait rendre les sensations vécues et créer des images visuelles dont la concision, les registres, les contrastes atteignent une beauté qui me soigne de l’effroi, et m’offrent une qualité d’émotion au moment où ce qui est décrit me dessoude de mon humanité. Ses livres racontent des solidarités qui ont permis à certaines de survivre, et comment la culture personnelle a pu agir pour agrandir la conscience de soi, la perspective de son destin. Son écriture prend le chemin inverse des images de l’extermination de masse. Pour lire une des plus grandes tragédies de l’histoire, elle accorde au lecteur de l’espace et du temps et montre la nécessité de ces deux notions pour exister comme sujet pour soi, dans la société, dans le monde.
Le rôle du cadre de santé dans la perte et la (re)construction de sens au travail à l’hôpital. Une étude exploratoire par entretiens semi-directifs auprès du personnel soignant
Authors: Moisson Virginie , Gardody Jérôme 
Published: April 2021

Cet article présente les résultats d’une étude qualitative exploratoire menée auprès d’infirmières confrontées à une construction/perte de sens au travail ainsi que le rôle que peut potentiellement jouer le cadre de santé dans cette relation. L’étude porte ainsi sur le management du sens au travail dans le contexte spécifique des établissements de santé. Il s’agit de répondre à la question de recherche : comment construire ou reconstruire le sens au travail dans les établissements de santé ? Une analyse de contenu des données recueillies à partir de 19 entretiens semi-directifs est réalisée et met en exergue les déterminants de ce qui fait sens et de ce qui nourrit la perte de sens pour le personnel soignant questionné. Il apparaît que les quatre dimensions du modèle SLAC (Sens/Lien/Activité/Confort) développé par Abord de Châtillon et Richard (2015) sont retrouvées dans les propos recueillis. En effet, au regard de nos résultats empiriques 3 dimensions (Lien, Activité et Confort) semblent constituer des facteurs de la construction de sens et des leviers pour sa reconstruction par les cadres de santé.
Some Basic Facts About Models, Nursing Conceptualizations, and Nursing Theories
Authors: Capers Cynthia Flynn 
Published: April 2021

ABSTRACT
The continuing education content pertinent to an introduction of models, nursing conceptualization, and nursing theories for nurses is specified. Teaching methods are described and illustrations given. The author states experiences in using these guidelines for continuing education to prepare practicing nurses for use of the Neuman Systems Model as a conceptualization for nursing practice.
Meeting the Continuing Education Needs of Nurses in Rural Settings
Authors: Anderson Jamie , Kimber Karen 
Published: April 2021

ABSTRACT
Access to continuing education (CE) for rural nurses is hampered by distance, cost factors, and the lack of sufficient personnel to provide coverage when nurses are away from work. Additionally, because rural nurses function as generalists rather than specialists, CE programs should focus on the generalist perspective. The Nevada Area Health Education Center (AHEC) has developed a partnership model for providing CE that addresses these considerations, bringing educational programs to the rural site eliminates travel, cost, and coverage problems for the hospitals. In turn, a close working relationship between AHEC and rural personnel to assess needs and coordinate the planning is critical. Attention to logistical detail is critical. The partnership model described is the foundation of a year-round CE program for nurses working in rural and frontier areas.
Self-Instructional Posters: One Way to Save Time and Money
Authors: Healey Kathleen M , Hoffman Marcia A 
Published: April 2021

ABSTRACT
Getting staff to continuing education programs can be difficult due to time, staffing, and cost restraints. A self-instructional module combined with a teaching poster format has had a favorable response from participants. This format has the capability of reaching a higher number of participants and is both time- and cost-effective.
Blueprint for Proficient Practice: An Adult Medical-Surgical Nursing Orientation Program
Authors: Angelucci Donna , Todaro Arleen 
Published: April 2021

ABSTRACT
Medical-surgical nursing is a speciality that is long overdue for acknowledgment. Our hospital orientation program provides an integration of theory and practical experience using the principles of adult learning.
Faculty maintain "facilitator" rather than "instructional" roles and develop supportive and collaborative relationships with the new nurse. Its concise plan and design is intended to have a favorable impact on professional nursing practice and patient care outcomes. In addition, the program has promoted a recruitment advantage in today's arena of educational competitiveness.
A Psychoeducational Model for Changing Nurses' AIDS Knowledge, Attitudes, and Practices
Authors: Flaskerud Jacquelyn H 
Published: April 2021

ABSTRACT
A review of the research literature over the last five years reveals that nurses' knowledge of the human immunodeficiency virus (HIV) has improved dramatically. However, attitudes and fears about HIV and acquired immunodeficiency syndrome (AIDS) have not changed commensurately with nurses' knowledge. Also, there is evidence that nurses' clinical practice is not always safe. This paper summarizes the research literature and proposes a three-tiered psychoeducational model for changing knowledge and clinical skills, knowledge and attitudes, and attitudes alone. These approaches include information and demonstration, expression of attitudes and fears, role-playing, group discussions, practice in designing policies, and exposure to various socioculturel groups, to persons with HIV, and to religious, legal, and ethical spokespersons.
Data Collection as an Educational Process
Authors: Bostrom Janet , Dibble Suzanne , Rizzuto Carmela 
Published: April 2021

ABSTRACT
Data collection, an experiential method for learning about the research process, may affect the attitudes and future research involvement of nurse data collectors. This study describes the effects of the data collection experience on nurses' perceptions of nursing research and the research environment and on their plans for research involvement. Implications of using the data collection experience as an educational process about research are included.
Differentiating Impact Evaluation From Evaluation Research: One Perspective of Implications for Continuing Nursing Education
Authors: Waddell Donna L 
Published: April 2021

ABSTRACT
Practitioners of continuing nursing education need to be able to distinguish between impact evaluation and evaluation research reported in the literature. Failure to do so may lead to invalid conclusions or faulty decision-making. This article defines impact evaluation and evaluation research, compares them across seven dimensions, and describes their strengths and weaknesses.
Formative Evaluation of a Nursing Orientation Program: Self-Paced vs. Lecture-Discussion
Authors: Grant Patricia 
Published: April 2021

ABSTRACT
Formative program evaluation is a useful process to assess the effectiveness and stability of changes in a program over time. This process documented the effectiveness of changing a medical center nursing orientation program from traditional lecture-discussion to self-learning modules (SLMs). The results of the formative program evaluation confirmed that SLMs were the method of choice for most learners. SLMs focus on adult learning principles more than traditional methods, i.e., lecture-discussion. However, the results of this program evaluation also indicate that staff development educators need to vary teaching methods along with the use of SLMs.
Developing a Community-Wide HIV/AIDS Nurse Education Series: A Strategy for Success
Authors: Lachat Maryanne F , Cowen Edward R 
Published: April 2021

ABSTRACT
The need for continuing nursing education in the area of HIV/AIDS care and prevention has intensified. Planning community-wide HIV/AIDS programs is a challenge. This article describes a strategy that was successful in consolidating multiagency expertise and in establishing a framework for subsequent continuing education programs.
Individualized Enhancement Programs for Nurses that Promote Competency
Authors: Rath Darlyne , Boblin-Cummings Sheryl , Baumann Andrea , Parrott Eric , Parsons Marilyn 
Published: April 2021

ABSTRACT
Working in a cost-conscious health care environment changes the accessibility to conferences, workshops and other continuing education offerings. Educators, employers and individual nurses are compelled to be innovative in their approach to maintaining competency through continuing education (CE). Greater emphasis must be placed on effectively matching CE programs with carefully targeted learning needs. This article illustrates a four-phase approach to an individualized enhancement program that incorporates job expectations and competencies. The phases are: 1) completing a needs assessment, 2) defining learning objectives, 3) assessing available learning resources, and 4) evaluating the CE experience.