bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functional outcomes in the inpatient rehabilitation setting following severe COVID-19 infection
Authors: Olezene Cameron Spencer , Hansen Elizabeth , Steere Hannah K. , Giacino Joseph T. , Polich Ginger R. , Borg-Stein Joanne , Zafonte Ross D. , Schneider Jeffrey C. 
Published: March 2021

Objective
To characterize the functional impairments of a cohort of patients undergoing inpatient rehabilitation after surviving severe COVID-19 illness, in order to better understand the ongoing needs of this patient population.

Methods
This study consisted of a retrospective chart review of consecutive patients hospitalized for COVID-19 and admitted to a regional inpatient rehabilitation hospital from April 29th to May 22nd, 2020. Patient demographics, clinical characteristics and complications from acute hospitalization were examined. Measures of fall risk (Berg Balance Scale), endurance (6 Minute Walk Test), gait speed (10 Meter Walk Test), mobility (transfer and ambulation independence), cognition, speech and swallowing (American Speech and Hearing Association National Outcomes Measurement System Functional Communication Measures) were assessed at rehabilitation admission and discharge.

Results
The study population included 29 patients and was 70% male, 58.6% white and with a mean age of 59.5. The mean length of acute hospitalization was 32.2 days with a mean of 18.7 days intubated. Patients spent a mean of 16.7 days in inpatient rehabilitation and 90% were discharged home. Patients demonstrated significant improvement from admission to discharge in measures of fall risk, endurance, gait speed, mobility, cognition, speech and swallowing, (p< 0.05). At discharge, a significant portion of the population continued to deficits in cognition (attention 37%; memory 28%; problem solving 28%), balance (55%) and gait speed (97%).

Conclusion
Patients admitted to inpatient rehabilitation after hospitalization with COVID-19 demonstrated deficits in mobility, cognition, speech and swallowing at admission and improved significantly in all of these domains by discharge. However, a significant number of patients exhibited residual deficits at discharge highlighting the post-acute care needs of this patient population.
Zaratustra e o Fracasso Pedagógico
Authors: De Brito Maria dos Remédios 
Published: March 2021

Zaratustra e o fracasso pedagógico 1
Resumo: O presente texto toma o Prólogo da obra Assim Falou Zaratustra, precisamente, aquilo que se pode chamar de fracasso pedagógico. O argumento é que Zaratustra não fracassa ao dialogar com o povo na praça do mercado, mas faz desse encontro o seu primeiro ato fundamental de formação e aprendizado.
Palavras-chave: Zaratustra; Formação; Fracasso Pedagógico.
Zaratustra y el fracaso pegagogico 1
Resumen: El presente texto toma el prólogo de la obra Así habló Zaratustra, precisamente, lo que podría llamarse el fracaso pedagogico. El argumento es que Zaratustra no fracasa deja de diálogo con las personas en la plaza del mercado, pero este encuentro su primer acto fundamental de la formación y el aprendizaje.
Palabras clave: Zaratustra; Formación; El fracaso pedagógico.
Zarathustra and the pedagogical failure 1
Abstract: The following text takes the prologue of Thus Spoke Zarathustra, precisely, that which may be called a pedagogical failure. The argument herein is that Zarathustra does not fail when he dialogues with people in the market square; instead he turns this encounter into his first fundamental act of formation and learning.
Keywords : Zarathustra; Formation; Pedagogical Failure
Data de registro: 30/01/2020
Data de aceite: 27/05/2020
[1] 'Pedagógico é relativo à pedagogia, que tem como etimologia gr. Paidagõgía, direção ou educação da criança. Do lat. Paedagõga (lex), lei que serve de guia'. (Cf: Dicionário Houaiss da língua portuguesa. Instituto Antonio Houaiss. Rio de Janeiro: Objetiva, 2001.) Contudo, gostaria de enfatizar que o termo "pedagógico" não será entendido neste trabalho como um conjunto de métodos, de direção, de técnicas de ensino e de condução. A sua utilização demanda, neste estudo, sentidos de criação, tornar-se, superar-se, ou seja, constituir-se. Dessa maneira, inspira uma perspectiva formativa. É assim que este termo pode ser lido neste texto, ou seja, toma uma leitura diferenciada do que seja a sua própria etimologia.
Kollaborative Wege in die Smart City
Authors: Ortiz André , Ludwig Dorothea , Pollmüller Frithjof , Becker Daniela , Noll Florian 
Published: March 2021

Im Mittelpunkt dieses Beitrags steht ein kollaborativer Ansatz zur Entwicklung eines dynamischen Wärmekatasters, das als Planungs­instrument für die Wärmewende in der Smart City und zur Erreichung des Ziels klimaneutraler Städte dienen soll. Vor diesem Hintergrund wird aufgezeigt, wie in einem transdisziplinären Technikentwicklungsprozess Elemente der Nutzer*innenbeteiligung zum Tragen kommen und wie auf diese Weise ein an die mehrschichtigen Anforderungen der Stakeholder angepasstes Instrumentarium entwickelt werden kann.
Intellectual Capital and Firm Performance of Listed Firms in Nigeria: Moderating Role of Corporate Governance
Authors: Adegbayibi Adesanmi Timothy 
Published: March 2021

The low performance of Nigerian firms despite investment in intellectual capital is a major concern. While studies have shown that corporate governance practices strengthens the subsisting relationship between investment in intellectual capital and performance in the developed economies, this moderating effect in Nigeria is yet to be adequately explored as research focus is limited to possible effects of intellectual capital and performance. It is against this background, this study investigated the moderating role of corporate governance on the relationship between intellectual capital and performance of listed non-financial companies in Nigeria. The study adopted ex-post facto research design, and data were drawn from the audited annual reports of fifty (50) listed non-financial firms for a period of 2007 to 2017. Multiple regression techniques were employed to test the relationship among the variables. The results of the study revealed that both intellectual capital and corporate governance drive financial performance as the relationship is found significant in all components. The study concluded that corporate governance moderated the effect of investment in intellectual capital on financial performance. The study recommends that Board of directors should adopt measurable corporate governance mechanism which strengthens and helps in investment strategy that increases and improves performance. Also, there is need to entrench corporate governance as a control strategy and impetus towards attaining organization’s goals.
Investigation on ultrasonic assisted friction stir welding of aluminum/steel dissimilar alloys
Authors: Hong Kairong , Wang Yong , Zhou Jianjun , Zhou Canfeng , Wang Luming 
Published: March 2021

Abstract
The extensive use of light metal material such as aluminum has brought about problems in its joining with steel. However, the weak metallurgical bonding between the dissimilar materials and the formation of hard and brittle intermetallic compounds (IMCs) lead to unsatisfactory joint strength. Aiming at achieving high-quality joining of aluminum and steel, 6061-T6 aluminum and 301L steel alloys were lap joined by ultrasonic assisted friction stir lap welding (UaFSLW) in this study. The UaFSLW joints were well formed with uniform flashes and even arc lines. The strong plastic flow of the aluminum material driven by the dual effects of mechanical stirring and ultrasonic vibration inhibited the excessive growth of the Al–Fe IMCs at the lap interface. Thanks to the enhanced metallurgical bonding and the effective control of the layer thickness of IMCs, the tensile load of the UaFSLW joint under 1,800 rpm reached 16.5 kN, which was an increase of 27.9% compared to that of the conventional FSLW joint.
On the inverse problem for nonlinear strongly damped wave equations with discrete random noise
Authors: Triet Nguyen Anh , Tuan Nguyen Huy , Phuong Nguyen Duc , O’ Regan Donal 
Published: March 2021

Abstract
In this paper, we consider the existence of a solution u(x, t) for the inverse backward problem for the nonlinear strongly damped wave equation with statistics discrete data. The problem is severely ill-posed in the sense of Hadamard, i.e., the solution does not depend continuously on the data. In order to regularize the unstable solution, we use the trigonometric method in non-parametric regression associated with the truncated expansion method. We investigate the convergence rate under some a priori assumptions on an exact solution in both L
2 and H

q
(q > 0) norms. Moreover, a numerical example is given to illustrate our results.
Modulatory effect of methanol extract of Annona muricata stem bark on mitochondrial membrane permeability transition pore in normal rat liver and monosodium glutamate-induced uterine hyperplasia
Authors: Olowofolahan Adeola Oluwakemi , Adewoye Funmilayo O. , Olorunsogo Olufunso Olabode 
Published: March 2021

Abstract

Objectives
Uterine fibroids are benign tumors that develop in many women of reproductive age. Surgery is the main approach to treatment while other options are also associated with adverse effects. Studies have shown that certain bioactive agents present in medicinal plants elicit their anti-tumor activity by induction of mitochondrial permeability transition (mPT) opening. This research therefore aimed at investigating the effect of methanol extract of Annona muricata (MEAM) on mPT pore opening in normal and monosodium glutamate-induced uterine hyperplasia using female Wistar rats.

Methods
Mitochondria, isolated from rat liver were exposed to different concentrations (20, 60, 100, 140 and 180 μg/mL) of MEAM. The mPT pore opening, cytochrome c release, mitochondrial ATPase (mATPase) activity and the percentage lipid peroxidation were assessed spectrophotometrically. Histological effects of MEAM on the liver, brain and uterus of normal and MSG-treated rats were investigated.

Results
The in vitro results showed a significant induction of mPT pore opening by 2.4, 4.2 and 6.4 folds, release of cytochrome c and enhancement of mATPase activity at 100,140 and 180 μg/mL, respectively. However, oral administration of MEAM did not induce mPT pore opening, neither any significant release of cytochrome c nor enhancement of mATPase activity at all the dosages used. However, histological assay revealed the presence of MSG-induced cellular damage and uterine hyperplasia which was ameliorated by MEAM co-administration.

Conclusions
These findings suggest that MEAM contains phytochemicals that can ameliorate MSG-induced damage and uterine hyperplasia in rats; however, the mechanism might not be via upregulation of mitochondrial-mediated apoptosis.
The effects of combination of Zingiber officinale and Echinacea on alleviation of clinical symptoms and hospitalization rate of suspected COVID-19 outpatients: a randomized controlled trial
Authors: Mesri Mehdi , Esmaeili Saber Seied Saeid , Godazi Mohammadreza , Roustaei Shirdel Aboulfazl , Montazer Reza , Koohestani Hamid Reza , Baghcheghi Nayereh , Karimy Mahmood , Azizi Nemat 
Published: March 2021

Abstract

Objectives
Herbal medicines, as a treatment method, have received a great deal of attention. The effects of two herbal medicines namely Zingiber officinale and Echinacea on alleviation of clinical symptoms and hospitalization rate of suspected COVID-19 outpatients were examined.

Methods
A clinical trial with 100 suspected COVID-19 outpatients as participants was conducted. The participants were allocated randomly to two groups of 50 members. The intervention group received concurrent Zingiber officinale (Tablet Vomigone 500 mg II tds) and Echinacea (Tablet Rucoldup I tds) for seven days in addition to the standard treatment. The control group only received the standard treatment (Hydroxychloroquine). After seven days, alleviation of clinical symptoms and hospitalization rate were examined. In addition, 14 days after treatment, the hospitalization was assessed again by telephone follow up.

Results
The two groups were identical in terms of basic characteristics. Improvement level as to coughing, dyspnea, and muscle pain was higher in the intervention group (p value <0.05). There was no significant difference between the two groups in terms of the other symptoms. In addition, the hospitalization rate in the intervention and control groups were 2 and 6% respectively, which are not significantly different (p value >0.05).

Conclusions
Taking into account the efficiency and trivial side-effects of Zingiber officinale and Echinacea, using them for alleviation and control of the clinical symptoms in COVID-19 outpatients is recommended.
Crystal structure of poly[(m3-3-carboxyadamantane-1-carboxylato-κ3
O:O′:O″)-(phenanthroline-κ2
N,N′)sodium(II)], C24H23N2NaO4
Authors: Li-Hua Wang , Li-Li Liu , Shu-Hua Cao , Xi-Shi Tai 
Published: March 2021

Abstract
C24H23N2NaO4, monoclinic, P21/c (no. 14), a = 7.5246(5) Å, b = 22.554(2) Å, c = 11.3358(9) Å, β = 91.881(7)°,V = 1922.8(3) Å3, Z = 4, R

gt
(F) = 0.0496, wR

ref
(F
2) = 0.1184, T = 100K.
A Novel Three-Choice Touchscreen Task to Examine Spatial Attention and Orienting Responses in Rodents
Authors: Haddad Faraj L. , Ghahremani Maryam , De Oliveira Cleusa , Doornaert Ella E. , Johnston Kevin D. , Everling Stefan , Schmid Susanne 
Published: March 2021

AbstractMammalian orienting behavior consists of coordinated movements of the eyes, head, pinnae, vibrissae, or body to attend to an external stimulus. The present study aimed to develop a novel operant task using a touch-screen system to measure spatial attention. In this task, rats were trained to nose-poke a light stimulus presented in one of three locations. The stimulus was presented more frequently in the center location to develop spatial attention bias toward the center stimulus. Changes in orienting responses were detected by measuring the animals’ response accuracy and latency to stimuli at the lateral locations, following reversible unilateral chemogenetic inactivation of the superior colliculus (SC). Additionally, spontaneous turning and rotation behavior was measured using an open-field test (OFT). Our results show that right SC inactivation significantly increased the whole body turn angle in the OFT, in line with previous literature that indicated an ipsiversive orientating bias and the presence of contralateral neglect following unilateral SC lesions. In the touch screen orienting task, unilateral SC inactivation significantly increased bias toward the ipsilateral side, as measured by response frequency in various experimental conditions, and a very large left-shift of a respective psychometric function. Our results demonstrate that this novel touchscreen task is able to detect changes in spatial attention and orienting responses because of e.g. experimental manipulations or injury with very high sensitivity, while taking advantage of the touch screen technology that allows for high transferability of the task between labs and for open-source data sharing throughhttps://www.mousebytes.ca.
The Human Osteological Collection of Vilnius University
Authors: Kozakaitė Justina , Brindzaitė Rūta , Miliauskienė Žydrūnė , Žalnora Aistis , Jankauskas Rimantas 
Published: March 2021

This article briefly presents the history of the human osteological collection stored at the Faculty of Medicine of Vilnius University. The birth of such collection can be traced back to the mid-19th century (1855) with the establishment of the Museum of Antiquities. Until the mid-20th century, human skeletal remains were gathered sporadically and selectively, by collecting either skulls or long bones. Since the late 20th century, the policy of selection has changed and nowadays the collection consists of systematically assembled anthropological material of scientific value. The assemblage currently comprises more than 9.000 skeletal remains dating back from the Mesolithic to the Late Modern Era.
Pendugaan Umur Simpan Tiwul Instan yang Dikemas dalam Aluminium Foil dan Polietilen dengan Metode Akselerasi Berdasarkan Pendekatan Kadar Air Kritis
Authors: Agustia Friska Citra , Rukmini Herastuti Sri , Naufalin Rifda , Ritonga Abdul Mukhlis 
Published: March 2021

Penelitian bertujuan untuk menentukan umur simpan tiwul instan tinggi protein yang dibuat dari tepung ubi kayu dengan perlakuan modifikasi mikrobiawi dan kimiawi yang dikemas dalam kemasan aluminium foil dan plastik polietilen yang dihitung menggunakan metode akselerasi berdasarkan pendekatan kadar air kritis. Penelitian ini menggunakan metode eksperimental. Modifikasi mikrobiawi dilakukan dengan memfermentasi ubi kayu dengan ragi tape 4% dan diinkubasi selama 6 jam, sedangkan perlakuan kimiawi adalah dengan cara merendam ubi kayu dalam larutan soda kue selama 15 menit. Tiwul instan selanjutnya dibungkus dalam kemasan aluminium foil dan kemasan plastik polietilen. Kadar air tiwul dan tekstur dianalisis selama penyimpanan. Pembuatan pola kurva isotherm sorpsi air dan penghitungan masa simpan produk juga dilakukan pada penelitian ini. Hasilnya, tiwul instan perlakuan modifikasi kimiawi pada ubi kayu mempunyai masa simpan sekitar dua kali lipat dari perlakuan modifikasi mikrobiawi, yaitu masing-masing selama 4,88 tahun dan 2,13 tahun (yang disimpan dalam polietilen) serta 8,55 dan 3,89 tahun (yang disimpan dalam aluminium foil). Kesimpulannya, pendekatan titik air kritis dapat dilakukan untuk mendeteksi masa simpan tiwul instan, baik yang dikemas dalam aluminium foil maupun kemasan polietilen yang dapat menghasilkan masa simpan tiwul instan.“High Protein Instant Tiwul” Shelf Life Packed with Aluminum Foil and Polyethylene Using Critical Moisture Content ApproachAbstractThe research aims to determine the shelf life of high protein instant tiwul made from cassava flour with chemical and microbial modification packed in aluminum foil and polyethylene plastic packaging using the acceleration method with the critical moisture content approach. Fermented cassava (at 4% concentration for 6 hours incubation) was used as microbial modification treatment while cassava immersed in baking soda solution for 15 minutes was also applied as chemical modification. Instant tiwul was then packaged using aluminum foil and polyethylene. Moisture content of instant tiwul was determined during storage while water sorption isotherm curve patterns was also generated. Instant tiwul of cassava with chemical modified treatment had twice in shelf life, longer than those of microbial modification treatment, resulting 4.88 and 2.13 years (using polyethylene package) while 8.55 and 3.89 years (using aluminum foil), respectively. As conclusion, critical moisture approach could be used in the detection of shelf life in instant tiwul with polyethylene and aluminum foil packaging.
A comparative study of topical fixed dose combination of brimonidine (0.2%) plus brinzolamide (1%) versus brimonidine (0.2%) plus timolol (0.5%) in patients of primary open angle glaucoma
Authors: Rastogi P S , Jain Kanupriya , Chander Ashish , Ansari Munavvar 
Published: March 2021

Primary open-angle glaucoma (POAG), fundamentally results from impaired or suboptimal drainage of aqueous humor from the eye through the trabecular meshwork and/or uveoscleral pathways.: the purpose of our study was to compare the efficacy and safety of Brimonidine 0.2% plus Brinzolamide 1% versus Brimonidine 0.2% plus Timolol 0.5% in patients with Primary Open Angle Glaucoma. A total of 81 subjects including 84 eyes in group I (brimonidine plus timolol) and 78 eyes in group II (brimonidine plus brinzolamide) with open angle glaucoma were enrolled. The detailed glaucoma examination was done. IOP measurements at 9 am, 12 pm and 3 pm, during week 2, 4, 8 and 12 were used to assess efficacy. Adverse events were recorded. The statistical test used were Chi-square test, Unpaired t-test and Paired t-test. Majority of patients in group I obtained an IOP reduction of &#62;30% at 9.00 am 92.3%), 12.00 pm (91.3%) and 3.00 pm (86.2%) after 12 weeks of therapy. Majority of patients in group II obtained an IOP reduction of &#62;30% at 9.00 am (86.8%), 12.00 pm (87.7%) and 3.00 pm (71.9%) after 12 weeks of therapy. Both drugs can thus be useful as second line therapy in the management of patients with POAG uncontrolled on monotherapy. Moreover, each drug has provided significant mean IOP reduction after three month of therapy at all visits and at all times.
Proportion of various ophthalmic ailments and causes among the participants on their first visit to a tertiary care ophthalmic OPD- A cross sectional survey from south central Kerala
Authors: Lukose Sumi , Koshy Shaji P , Thomas Pramod 
Published: March 2021

Blindness, loss of eyesight, could be temporary or permanent. Damage to any portion of the eye, optic nerve or the brain that is responsible for this function results in visual impairment. The commonest causes for blindness are cataract, refractive errors, glaucoma, corneal opacities. Assess major causes of visual impairment among new patients visiting ophthalmology OPD. : Study conducted using a cross sectional survey design. Data collected from ophthalmology OPD of a tertiary care hospital.The proportion of ocular diseases, degree of blindness and causative factors were assessed and recorded. Patient’s visual impairment status was classified as mild, moderate, severe and blind according to WHO classification for visual impairment and blindness (Oct. 2019). Visual acuity, auto refraction, colour vision, intra ocular pressure measurement, slit lamp and fundus examinations were carried out. Data Entry: MS Excel. Statistics: chi square, proportions. There were 303 participants, 42.2% males and 57.8% females and 0.3% were blind, 1% severely visually impaired, 3.3% moderately impaired, 4% mildly impaired. Among the 106 diabetic patients, 30 diabetic retinopathy cases were observed. There were 1.02% participants with impaired colour vision, refractive errors 54.8%, cataract 35.4%, diabetic retinopathy 9.9%, glaucoma 9.2%. Refractive error and cataract were most frequent. Color blindness was less common. Cataract and glaucoma was not observed before 40 years of age. Visual impairment across regions are similar, refractive error and cataract were leading causes of visual impairment.
Cortical Activation Changes Associated with Autonomous Sensory Meridian Response (ASMR): Initial Case Report
Authors: Seifzadeh Sahar , Moghimi Ebrahim , Torkamani Fatemeh , Ahsant Negar 
Published: March 2021

The Autonomous Sensory Meridian Response (ASMR) is a unique phenomenon to provoke a sense of relaxation that has been proposed for a few years. This phenomenon suggests acoustic-visual stimuli for cultivating a peaceful environment for the mind as well as a tingling sensation. Some studies suggest that this phenomenon is comparable with mindfulness; surprisingly, published articles in this regard are growing increasingly to examine how it happens scientifically. Some studies have been done on neuroimaging techniques, including functional Magnetic Resonance Imaging (fMRI), biological methods such as heart rate and skin conductance, and questionnaires to assess the impact of ASMR videos. In this paper, we intend to determine the effect of ASMR videos on EEG signals. The FFT absolute power analysis (Pre versus Post ASMR) revealed a declined delta band power generally. On the other hand, there are no significant changes in theta band power. The central region demonstrated a rise in alpha band power as well as a slight decrease in the occipital region. Moreover, such an increase was evident in post-ASMR in the beta1 (Sensorimotor wave (12-15 Hz)) band frequency, generally, especially in the frontal region. Besides, Gamma 1 has been increased in the central region, and Gamma 2 has also be increased in frontoparietal regions in both hemispheres. These results indicate the cognitive process as well as sensorimotor, tingling sensations features of ASMR.