bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimental study on the expression and diagnostic significance of I-FABP in acute intestinal ischemia
Authors: Li Haikun , Wang Minhua , Zhu Xiansen , Zhou Xiaoqing , Yang Bin , Yin Qinghui , Liu Xiaoping , Zeng Xiangfu , Hu Yan , Zeng Xiangtai 
Published: November 2021

Objective: To detect the expression and distribution of I-FABP in intestinal tissue and the changes of serum concentrations at different time of acute intestinal ischemia, and explore the significance and mechanism of I-FABP in early diagnosis of acute ischemic bowel disease. Methods: The selected 96 healthy adult SD rats were randomly divided into the experimental group and control group; 48 in each group. Each group was randomly subdivided into 6 groups with 8 rats in each group. The superior mesenteric artery was ligated in the experimental group and the peritoneal switch operation was performed in the control group. The venous blood samples were extracted from each group rats’ right ventricle at 0.5 h, 1 h, 2 h, 4 h, 8 h, 12 h after the operation and the concentration of I-FABP was tested respectively. Then the rats were killed, and the diseased intestinal tubes were cut out for paraffin sections. The I-FABP in intestinal tissue was stained by routine HE staining and direct immunofluorescence staining. Results: The I-FABP was mainly expressed in the epithelial villi of intestinal mucosa, and there was a small amount of expression in the intestinal submucosa and even the muscularis. Within 1 hour of intestinal ischemia, the number of I-FABP positive granules in the intestine and intestinal cavity increased gradually, and then gradually decreased after 1 hour. The difference has statistically significant between the experimental group and the control group (P < 0.05). The serum I-FABP: In the experimental group, the serum I-FABP concentration began to increase at 0.5 h, and reached a peak at 1 h (290. 24 ± 156.69) μg·L–1, then gradually decreased. Compared with the control group, the difference was statistically significant (P < 0.05). Conclusion: I-FABP usually mainly exists in the epithelial cells of intestinal mucosa. When acute intestinal ischemia occurs, the epithelial cells of intestinal mucosa permeability changes; I-FABP expression rapidly releases to intestinal tissue and intestinal cavity, and is absorbed into the blood. Therefore, I-FABP has certain clinical significance in early diagnosis and treatment of acute intestinal ischemia.
Teleonomía y función biológica. Una investigación sobre las raíces y las virtualidades de la teleonomía según Konrad Lorenz
Authors: Durieux Montoya Laura 
Published: November 2021

Esta investigación trata de la cosmovisión reflexiva y crítica sobre el papel de la finalidad en la biología elaboradas por Konrad Lorenz. Se trata de una investigación en filosofía y no en biología, por lo que las principales aportaciones de Lorenz a la Etología se insertan en el marco teórico definido por los conceptos de (i.) organismo en Kant, (ii.) evolución adaptativa en Darwin y (iii.) recuperación de la finalidad como teleonomía. Lorenz rechaza la teleología de raigambre aristotélica, y propone un modelo teórico en biología de raíces kantianas y hartmantianas. Se trata de un modelo explicativo en biología. Mi intención en esta investigación radica en explorar las raíces y las virtualidades del modelo explicativo de la finalidad en biología propuesto por el etólogo austriaco.
About uniformly Lindelöf spaces
Authors: Kanetov Bekbolot E. , Saktanov Ulukbek A. , Zhanakunova Meerim O. 
Published: November 2021

Abstract
The idea of Lindelöfness is one of the most important in General Topology. There have been some variants in defining uniformly Lindelöfness of uniform spaces. For example, uniform A-Lindelöfness in the sense of L.V. Aparina [1], uniform B-Lindelöfness in the sense of A.A. Borubaev [2], uniform I-Lindelöfness in the sense of D.R. Isbell [5].
In this paper we propose a new approach to the definition of a uniform analogue of Lindelöfness. We introduce and study uniformly Lindelöf spaces.
Optimization of the loading pattern of the PWR core using genetic algorithms and multi-purpose fitness function
Authors: Kubiński Wojciech , Darnowski Piotr , Chęć Kamil 
Published: November 2021

Abstract
The study demonstrates an application of genetic algorithms (GAs) in the optimization of the first core loading pattern. The Massachusetts Institute of Technology (MIT) BEAVRS pressurized water reactor (PWR) model was applied with PARCS nodal-diffusion core simulator coupled with GA numerical tool to perform pattern selection. In principle, GAs have been successfully used in many nuclear engineering problems such as core geometry optimization and fuel configuration. In many cases, however, these analyses focused on optimizing only a single parameter, such as the effective neutron multiplication factor (k
eff), and often limited to the simplified core model. On the contrary, the GAs developed in this work are equipped with multiple-purpose fitness function (FF) and allow the optimization of more than one parameter at the same time, and these were applied to a realistic full-core problem. The main parameters of interest in this study were the total power peaking factor (PPF) and the length of the fuel cycle. The basic purpose of this study was to improve the economics by finding longer fuel cycle with more uniform power/flux distribution. Proper FFs were developed, tested, and implemented and their results were compared with the reference BEAVRS first fuel cycle. In the two analysed test scenarios, it was possible to extend the first fuel cycle while maintaining lower or similar PPF, in comparison with the BEAVRS core, but for the price of increased initial reactivity.
Plasma technology to remove NOx from off-gases
Authors: Pawelec Andrzej , Chmielewski Andrzej G. , Sun Yongxia , Bułka Sylwester , Torims Toms , Pikurs Guntis , Mattausch Gösta 
Published: November 2021

Abstract
Operation of marine diesel engines causes significant emission of sulphur and nitrogen oxides. It was noticed worldwide and the regulations concerning harmful emissions were introduced. There were several solutions elaborated; however, emission control for both SOx and NOx requires two distinctive processes realized in separated devices, which is problematic due to limited space on ship board and high overall costs. Therefore, the electron beam flue gas treatment (EBFGT) process was adopted to ensure the abatement of the problem of marine diesel off-gases. This novel solution combines two main processes: first the flue gas is irradiated with electron beam where NO and SO2 are oxidized; the second stage is wet scrubbing to remove both pollutants with high efficiency. Laboratory tests showed that this process could be effectively applied to remove SO2 and NOx from diesel engine off-gases. Different compositions of absorbing solution with three different oxidants (NaClO, NaClO2 and NaClO3) were tested. The highest NOx removal efficiency (>96%) was obtained when seawater-NaClO2-NaOH was used as scrubber solution at 10.9 kGy dose. The process was further tested in real maritime conditions at Riga shipyard, Latvia. More than 45% NOx was removed at a 5.5 kGy dose, corresponding to 4800 Nm3/h off-gases arising from ship emission. The operation of the plant was the first case of examination of the hybrid electron beam technology in real conditions. Taking into account the experiment conditions, good agreement was obtained with laboratory tests. The results obtained in Riga shipyard provided valuable information for the application of this technology for control of large cargo ship emission.
Factores determinantes del tamaño del Sector no Lucrativo en las Comunidades Autónomas españolas
Authors: HernandezCalderón Milán Beatriz 
Published: November 2021

En este trabajo se analizan los factores determinantes del tamaño del Sector No Lucrativo en las Comunidades Autónomas españolas, a partir de las hipótesis que se derivan de las aportaciones teóricas más relevantes de la literatura económica en este ámbito. Para ello se realiza un análisis econométrico multivariante que somete a contraste las hipótesis propuestas por la teoría económica para las regiones españolas. Como fuente de información básica se utiliza la Encuesta a Directivos de Entidades, FONCE-2001. Los resultados del trabajo revelan que el tamaño del Sector No Lucrativo depende directamente: del tamaño del sector público y del sector de empresas lucrativas, lo que indica una relación de complementariedad entre los diferentes sectores institucionales y no de sustitución; del grado de heterogeneidad de demanda, lo que nos habla de que el Sector surge para atender parte de la demanda insatisfecha con la oferta de bienes colectivos; del grado de informa ción asimétrica lo que apunta que el Sector se dedica a la provisión de bienes de confianza; de la oferta de servicios de bienestar y de la sobrecarga del sector público, lo que muestra el papel que desempeña el Sector en la provisión y ampliación de los servicios de Bienestar; y del capital social que favorece la creación y promo ción de entidades no lucrativas desde el lado de la oferta.
Introducción a la gestión Stakeholder en las organizaciones no lucrativas. Una aproximación a través del estudio de casos*
Authors: HernandezSaz Gil M.ª Isabel 
Published: November 2021

La gestión de las Organizaciones No Lucrativas ha de orientarse tanto hacia la consecución de legitimidad social, como a la obtención de capacidades competitivas para hacer frente a los retos que tienen que afrontar. En este trabajo, se propone que la gestión Stakeholder permite alcanzar ambos requerimientos al fomentar la creación de capital social. El capital social existente en la red de relaciones de la organización se considera un recurso estratégico que favorece que la organización alcance sus objetivos organizativos. El estudio empírico se ha basado en la metodología cualitativa del estudio de casos, y el análisis realizado hace posible confirmar las proposiciones planteadas.
Valuación de activos intangibles con matemática difusa y su adecuación a normas contables españolas e internacionales
Authors: Mallo Paulino E. , Artola María Antonia , Morettini Mariano , Galante Marcelo J. , Pascual Mariano E. , Busetto Adrián R. 
Published: November 2021

El presente trabajo tiene por objetivo plantear una alternativa de valuación de activos intangibles a la luz de la importancia creciente que los mismos han adquirido en los últimos tiempos en relación a los bienes físicos o materiales.Específicamente, intentamos brindar una posibilidad de valuación de los bienes inmateriales a través de la utilización de la Matemática Difusa, y planteamos la compatibilidad de estas técnicas con los principios y requisitos de la información contable españoles e internacionales, a fin de que pueda incorporarse dicha valua ción a los estados contables preparados por las empresas.
Management of complex wounds treatment with a hydrofiber dressing in a public hospital in Bogota (Colombia)
Authors: Salazar Trujillo M. A. 
Published: November 2021

Objective. To evaluate the efficacy of the use of a last generation hydrofiber dressing with silver, for the treatment of complex wounds that are difficult to heal.Materials and research methods. A prospective observational case-follow-up study was carried out, which included patients with acute or chronic wounds that were difficult to heal, treated in the plastic surgery service of a public hospital in Bogota-Colombia, who underwent healing with hydrofiber dressings reinforced, with silver ions, benzethonium chloride and EDTA (Aquacel Agplus®, ConvaTec). The wound was monitored, evaluating infection control, exudate and biofilm, as well as the number of required dressings and the time required for the complete closure of the wound.Research results. A total of 55 patients were included, with a median age of 44 years. In all cases, a follow-up was carried out until the definitive closure of the wound. At the end of the study, it was observed that, in 35 (63.6 %) patients, the wounds evolved to complete closure by second intention in an average of 59.3 days, requiring 12.5 dressings. 20 (36.4 %) patients had adequate wound bed preparation for definitive surgical coverage with grafts, flaps or dermal substitutes, in an average of 31.4 days, requiring 6.5 dressings on average.33 (60.0 %) wounds were infected and adequate infection control was achieved on average with 5 dressings. A decrease in the direct and indirect signs of biofilm was achieved after 6 dressings.Conclusion. The results show that the dressing studied is effective to control exudate, infection and biofilm, as well as to prepare the bed for a definitive surgical coverage.
ВЛИЯНИЕ ДАВЛЕНИЯ ДЕТОНАЦИИ ВЗРЫВЧАТЫХ СОСТАВОВ НА ТЕПЛОТУ ВЗРЫВА
Authors: Сурначёв И.Н. , Певченко Б.В. , Курбатов А.В. , Пушкин Д.В. , Чеканов М.А. , Беляев В.А. , Петров Е.А. 
Published: November 2021

К настоящему времени накоплен большой объём калориметрических данных о теплоте (энергии) взрыва Q различных взрывчатых веществ (ВВ) и взрывчатых составов (ВС). Получены зависимости Q от начальной плотности ВВ Q(ρ0). Однако, на практике давление детонации в основном заряде можно менять, вызывая пересжатую детонацию, за счёт инициирования основного заряда мощным ВВ, поэтому практический интерес представляют зависимости теплоты взрыва от давления детонации Q(Р), которые можно получить на основе имеющихся зависимостей Q(ρ0) для индивидуальных ВВ, распространив их на ВС. Приведена методика определения зависимостей для расчёта теплоты взрыва различных ВС, включая алюминийсодержащие, как при нормальной так и при пересжатой детонации
A large volume of calorimetric data on the heat energy Q of explosion for various explosives (Es) and explosive compositions (EC) has been accumulated by now. The dependences of Q on the initial ES density Q (ρ0) are obtained. However, the detonation pressure in the base charge can be changed in practice causing super compressed detonation, due to the initiation of the base charge by a powerful explosive; therefore, the dependences of the explosion heat on the detonation pressure Q (P), which can be obtained on the basis of the available dependences Q (ρ0) for individual explosives is of practical interest as they can be applied to EC. A method to determine the dependences for calculating the heat of explosion of various aircraft, including aluminum-containing ones, both during normal and super compressed detonation is presented.
Employee Well Being and Work Life Balance as a Function of Job Satisfaction: The Moderating Role of Organisational Citizenship Behaviour
Authors: Adnan Muhammad , Bakhtawar Ayesha , Zahra Rakia Tul 
Published: November 2021

Purpose The goal of this study is to investigate that how Employee Well-Being and Work-Life Balance affected Job Satisfaction in healthcare centers with the moderating role of Organizational Citizenship Behavior.
Design/Methodology/Approach: Research was carried out in a quantitative approach. The healthcare centers of Multan region were chosen at random. Using a convenient sampling strategy, a questionnaire was created to collect data from different healthcare centers situated in Multan region. The Cronbach’s Alpha and Discriminant Validity were used to assess the questionnaire's reliability in the pilot phase. Descriptive and inferential statistical techniques (using Smart PLS) were used to assess quantitative data.
Findings: Employee Well-being and Job satisfaction have a positive relationship, whereas Work-Life Balance and Job satisfaction have a negative relationship, according to the results of this study. Organizational Citizenship Behavior (OCB) moderates Employee Well-being and Work Life Balance to Job satisfaction. Employee Well-Being is one of the major strengths for employee productivity, according to the findings of this research. When professionals practice Organizational Citizenship Behavior, employees' job satisfaction begins to rise in healthcare centers.
Implications/Originality/Value: This study was a complete report on Multan's healthcare centers that will be highly beneficial and instructive for policymakers and administration staff of healthcare centers for employee’s development, and for researchers in the Multan region to alter programs and policies according to the requirement for achieving goals
espacios comunales en las montañas septentrionales del reino de Valencia (s. XIII-XVI).
Authors: Royo Pérez Vicent 
Published: November 2021

En este artículo, se pretende analizar la gestión de los espacios comunales en las comarcas de Els Ports, El Maestrat y L’Alcalatén, en el norte del reino de Valencia. Desde el siglo xiv, los concejos de la región asumen la dirección de los bienes comunales y desarrollan una compleja normativa que regula su uso. Esta legislación se contiene en los llibres d’establiments y es fruto del consenso alcanzado entre las instancias de poder presentes en el ámbito local. Nuestra intención es estudiar estas fuentes con el fin de conocer el régimen de aprovechamiento de los espacios comunales que implantan las villas y las comunidades rurales, un sistema que intenta preservar los derechos colectivos frente a los intereses particulares.
Palabras clave: Comunidad rural, espacios comunales, llibres d’establiments, reino de Valencia, siglos XIII-XVI.
Abstract: In this article, we try to analyse the management of communal areas in Els Ports, El Maestrat and L’Alcalatén region, in the north of the Kingdom of Valencia. From 14th Century, councils of the region took over the management of the communal lands and developed a series of rules aimed at regulating the use. These laws were contained in the llibre d’establiments and were result of consensus achieved between the different powers existing in the local area. Our aim is to study these sources with the purpose of knowing how towns and rural communities were administering communal areas, with a system intended to keep the communal rights above private interests.
Keywords: Rural community, communal areas, llibres d’establiments, Kingdom of Valencia, 13th-16th Centuries.
Identification of risk factors associated with national transmission and late presentation of HIV-1, Denmark, 2009 to 2017
Authors: van Wijhe Maarten , Fischer Thea K , Fonager Jannik 
Published: November 2021

Background
Despite availability of pre-exposure prophylaxis (PrEP), the incidence of HIV-1 in Europe remained stable the past decade. Reduction of new HIV-1 infections requires more knowledge about the profiles of high-risk transmitters and late presenters (LP).

Aim
We aimed to investigate risk factors associated with HIV-1 transmission clusters and late presentation with HIV-1 in Denmark.

Methods
Blood samples and epidemiological information were collected from newly diagnosed HIV-1 patients between 2009 and 2017. We genotyped pol genes and performed phylogenetic analyses to identify clusters. Risk factors for clustering and LP were investigated with partial proportional odds and logistic regression. Covariates included transmission mode, HIV-1 subtype, age, origin and cluster activity.

Results
We included 1,040 individuals in the analysis, 59.6% identified with subtype B and 48.4% in a cluster. Risk factors for clustering included Danish origin (odds ratio (OR): 2.95; 95% confidence interval (CI): 2.21–3.96), non-LP (OR: 1.44; 95% CI: 1.12–1.86), and men who have sex with men (MSM). Increasing age and non-B subtype infection decreased risk (OR: 0.69; 95% CI: 0.50–0.94). Risk for late presentation was lower for active clusters (OR: 0.60; 95% CI: 0.44–0.82) and Danish origin (OR: 0.43; 95% CI: 0.27–0.67). Non-Danish MSM had a lower risk than non-Danish heterosexuals (OR: 0.34; 95% CI: 0.21–0.55).

Conclusion
HIV-1 transmission in Denmark is driven by early diagnosed, young, subtype B infected MSM. These may benefit most from PrEP. Non-Danish heterosexual HIV-1 patients could benefit from improved communication to achieve earlier diagnosis and treatment.
ANALISIS PENGARUH SIKAP TERHADAP MINAT BELI ONLINE MELALUI DROPSHIPPER PADA MEDIA E-COMMERCE
Authors: Nursakdah Nursakdah , Saufi Akhmad , Rinuastuti Baiq Handayani 
Published: November 2021

Tujuan penelitian ini adalah untuk mengetahui pengaruh sikap kognitif, afektif, dan konatif terhadap minat beli online melalui dropshipper pada media e-commerce. Populasi dalam penelitian ini adalah individu/masyarakat NTB yang berminat untuk berbelanja online melalui dropshiper. Teknik penentuan sampel yang digunakan pada penelitian ini adalah non-probability sampling dengan metode convenience sampling. Dengan metode convenience sampling, responden yang berhak mengisi kuesioner tergantung sepenuhnya kepada kemudahan penelitian. Analisis yang digunakan dalam penelitian ini adalah analisis PLS. Hasil penelitian membuktikan bahwa sikap berpengaruh terhadap minat beli online melalui dropshipper. Kata Kunci: Sikap Kognitif, Afektif, Konatif dan Minat Beli
The economic profitability of cereal production systems in the context of adaptation to climate change: the case of millet
Authors: OUMAROU DAN-BAKI Abdoul Azizou , TARNO Mamane 
Published: November 2021

This article studies the economic profitability of the millet production in a context of adaptation to climatic changes by considering the techniques of adaptation to soil protection, namely, low wall girdles tree and half-moon in order to determine their impact on the economic profitability of the production of this cereal.The economic model of profitability developed by Gnanglé and al. [15] is used to analyze this effect. The data used in this paper is obtained from the ministry of agriculture of Niger (ECVM/A 2015) and consists of 3,985 households from two regions of Niger, namely, the Maradi and Diffa regions. The results show that the techniques of "belt of tree" and "half-moon" increase the economic profitability of the millet production and that the effects are, respectively, 0.19 and 0.054 in the two areas. The econometric results show that these techniques are profitable in both areas. Given the effectiveness of these techniques, this study suggests that producers increase these practices in order to mitigate the effects of climate change on the millet production in Niger. Lastly, the government must popularize these techniques and support their use for a better adaptation of agriculture in these zones to climate change.
SOCIAL AND ECONOMIC DEVELOPMENT MODELS IN THE Digital transformation era
Authors: Bondarenko Valentina , Aleshkovski Ivan 
Published: November 2021

The article analyses development regularities of human system and investigates possible social and economic development models in the era of digital transformation. The article demonstrates that there are three models that can be applied in the conditions of Industry 4.0 technological revolution with its rapidly emerging digital devices and technology breakthroughs of the 21st century. These models are shaped in accordance with their development purposes, which can establish different relations between state, society, business, and specific individuals. The authors convincingly show that there is only one model capable of providing sustainable development and creating a new model for economic development, which corresponds to digital technologies of the 21st century.