bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hepatitis B Virus Infection as a Risk Factor for Developing Diabetes Mellitus: A Meta-Analysis of a Large Observational Studies
Authors: Sari Mutiara Nindya , Agdelina Clarissa , Bahri Darlene , Permata Nadya Regina , Trixie Joue Abraham 
Published: September 2021

Background: There are a lot of theories about how Hepatitis B Virus (HBV) infection affects many diseases, one of them is Diabetes Mellitus (DM). However, the relation remains controversial between DM and HBV as an infection. This study aims to evaluate HBV infection as a risk factor for developing DM.Method: A systematic review was performed using medical search engines such as Pubmed, ScienceDirect and GoogleScholar. References until February 2021 that met the inclusion criteria were reviewed. The primary outcome was the prevalence of DM. Authors also perform Subgroup analyses based on study type. The extracted data were analyzed using RevMan 5.4 application.Results: A total of 20 studies were analyzed with 245,468,411 subjects included. In which divided into two groups, patients with HBV infected group and non infected HBV group. Authors found that there is a statistically difference between patients with HBV infected groups and non infected HBV groups on the primary outcome which is the prevalence of DM (OR 1.24; 95% CI, 1.10-1.41; p = 0.0006). Authors also found the same results based on study type both in case-control (OR = 1.76; 95% CI: 1.08-2.85; p = 0.02) and cross-sectional (OR = 1.40; 95% CI: 1.05-1.85; p = 0.02) studies. Meanwhile in Cohort studies the results show no statistically significant difference between the two groups (OR = 1.07; 95% CI: 0.87-1.33; p = 0.52). Conclusion: HBV infected patients have a higher risk of developing DM than patients without HBV infection.
Features of microcirculation in psoriatic arthritis
Authors: Shishkin A. N. , Nikolaeva A. A. 
Published: September 2021

The literature review presents data on features of microcirculation in patients with psoriatic arthritis (PsA). The immune inflammation underlying PsA leads to increased permeability of the vascular wall, deposition of the immune complexes in it, a decreased capillary blood flow, and vascular sensitivity to sympathetic stimulation. In combination with impaired blood rheology during inflammation, these changes have a significant effect on the state of the microvasculature. Increased vascular permeability and a damaged connection between the endothelium and the extracellular matrix in PsA cause the formation of the capillaries with a pathological structure. Microscopic examination of the synovial membrane of patients with PsA shows vascular tortuosity, branching, and elongation. The duration, activity of articular inflammation, as well as severity of psoriasis are associated with the degree of microcirculatory disorders in PsA. The pathomorphological changes in the vessels of patients with PsA are detected not only in the articular tissues but also in the skin, which indicates dysregulation of angiogenesis in general. The mechanisms of the formation of new vessels with a pathological structure are not fully understood. However, most likely, an imbalance of the factors of angiogenesis and antiangiogenesis plays an important role. There is growing evidence that vascular endothelial growth factor (VEGF), transforming growth factor-beta (TGF-beta) and platelet growth factor (PDGF) are involved in the pathogenesis of PsA. At the moment, the issue of early diagnosis of PsA remains relevant, especially in cases with minor skin changes and rheumatoid-like joint lesions. Information on microcirculation obtained by capillaroscopy, video capillaroscopy, and fluorescence microscopy provides additional opportunities for a differential diagnosis of PsA, a determination of activity, and a prognosis of the disease.
Studi Literatur: Pelaksanaan Promotif dan Preventif Upaya Program Kesehatan Jiwa pada Puskesmas di Indonesia
Authors: Patricia Patricia Lydia Honey , Suryawati Chriswardani , Budiyanti Rani Tiyas 
Published: September 2021

Latar Belakang:
Kesehatan mental masih menjadi permasalahan kompleks yang mendapat perhatian khusus oleh seluruh dunia, termasuk di Indonesia. Banyaknya kasus yang meningkat menyebabkan menurunnya produktivitas masyarakat. Puskesmas sebagai penyedia pelayanan kesehatan memiliki fungsi mengedepankan upaya promotif dan preventif untuk meningkatkan derajad kesehatan jiwa di masyarakat.
Tujuan :
Penelitian ini bertujuan untuk menganalisis gambaran pelaksanaan Promotif dan Preventif upaya kesehatan jiwa pada Puskesmas yang dapat dilihat dari unsur SDM kesehatannya, metode yang digunakan untuk mencapai tujuan dan sarana/prasarana yang digunakan dalam mendukung pelaksanaan kegiatan.
Metode Penelitian:
Penelitian ini merupakan penelitian yang menggunakan simplified approach systematic literatur review. Pencarian literatur yang digunakan meliputi Science Direct, Pubmed, SpringerLink dan Google Scholar Literatur dengan kata kunci serta kriteria inklusi dan eksklusi yang telah ditetapkan.
Hasil :
Hasil penelitian menyatakan bahwa pelaksanaan upaya promotif dan preventif kesehatan jiwa di Indonesia berbeda dengan di luar negeri dalam tingkat perkembangannya. Pelaksanaan upaya kesehatan jiwa pada puskesmas di Indonesia sudah berjalan baik namun belum maksimal karena masih kurangnya pengetahuan keluarga, fasilitas dan infrastruktur yang seadanya sehingga perlunya pelatihan bagi kader kesehatan jiwa dan perawat dalam mengedukasi masyarakat, melakukan pendeteksian dini maupun penjangkauan pasien jiwa
Kesimpulan:
Pelaksanaan upaya promotif dan preventif oleh puskesmas tidak terlepas dari peran dan dukungan dari semua pihak terutama kader kesehatan jiwa dan pemberdayaan masyarakat. Ketersediaan sumber daya manusia yang memadai dan kompeten, mekanisme pelaksanaan yang sesuai dengan waktu dan program serta sarana dan prasarana merupakan prioritas penting dan menjadi tolak ukur keberhasilan program.
Managerial experience, fixed asset, and capital structure
Authors: Giovanni Axel , Muharam Harjum , Hirawati Heni , Sijabat Yacobo P 
Published: September 2021

This study empirically investigates the effect of managerial experience on capital structure and the role of fixed assets as the moderating variable in this relationship. Our research sample is all firms in the infrastructure, utilities, and transportation sectors listed at the Indonesian Stock Exchange in 2014-2018 based on the purposive sampling method. We analyze the research data with the ordinary least square (OLS) method. The results of our regression analysis show that managerial experience negatively affects capital structure. However, we find that fixed assets do not moderate the relationship between managerial experience and capital structure. Further analysis indicates that fixed assets moderate the relationship between managerial experience (MANXEP) and capital structure when MANEXP is measured with internal experience but not with the external one. Besides, the relationship between managerial experience and capital structure is significant when the fixed asset ratio is moderate or high. Overall, these findings indicate that studies on the effects of top managers/ CEOs’ characteristics on firms’ policies or performance should obtain and analyze more detailed measures of the CEOs’ characteristics or the context variables.
Placer y malestar en el trabajo: estudio de caso en futbolistas profesionales de equipos antioqueños
Authors: Cadavid Suárez Ricardo , Gañán Moreno Anderson , Orejuela Gómez Johnny Javier 
Published: September 2021

Esta investigación describe las experiencias de placer y malestar en el trabajo de un grupo de futbolistas profesionales de equipos antioqueños. Metodológicamente se clasifica como estudio de caso, de alcance descriptivo, de enfoque cualitativo y de corte transversal. Se presenta la entrevista realizada a cinco futbolistas profesionales. Con relación a los resultados, los sujetos entrevistados dicen experimentar placer cuando reciben reconocimiento y cuando se cumplen con las condiciones de trabajo, también a raíz de las amistades que se generan, y al tener buenas relaciones con los directivos del club y con la hinchada. Por otro lado, refieren que experimentan malestar cuando no hay un reconocimiento de orden económico esperado, cuando no hay óptimos espacios para entrenar o para concentrarse, además ante la planificación inadecuada para los momentos de entrenamiento o la recuperación de lesiones, y por los desencuentros con otros compañeros de trabajo.
La escuela y la migración: experiencias de niños venezolanos en Colombia
Authors: Millan Otero Katy Luz , Duran Palacio  Nicolasa María , Rodríguez Marin Laura Andrea , García Hincapié Andrea 
Published: September 2021

En los últimos años las transformaciones sociales, económicas y políticas de Venezuela han afectado la dinámica doméstica de la región y se han extrapolado más allá del continente, siendo la migración uno de sus efectos de mayor importancia histórica y coyuntural. El éxodo de los venezolanos hacia Colombia ha modificado no solamente la dinámica social del país de acogida, sino también las interacciones en las instituciones educativas, tras la incursión de niños y niñas migrantes. Esta investigación buscó analizar la experiencia de los niños venezolanos en las aulas de clase en la ciudad de Medellín. El horizonte de la investigación es cualitativo enmarcado en el método de estudio de caso que aporta descripciones densas con el propósito de interpretar y teorizar sobre la situación que es objeto de estudio. Se usó la entrevista semiestructurada y el mural de situaciones para la recolección de la información. Los hallazgos evidencian los desafíos que deben enfrentar los participantes en el nuevo país. En primer lugar, la xenofobia que por su condición de migrantes experimentan por parte de sus pares, quienes replican los estereotipos de los adultos exponiendo a los niños y niñas venezolanos a experiencias de “matoneo”. En segundo lugar, las dificultades para adaptarse al currículo colombiano y finalmente los tipos de duelo migratorios que deben elaborar, principalmente el duelo a la familia y amigos, a la lengua, la tierra y la cultura. Se discute el papel de la escuela como facilitador del proceso de inclusión de los estudiantes extranjeros.
Team idea mapping method: A brainstorming session for enhancing problem-solving skills in postgraduate medical biochemistry students as assessed by self-efficacy
Authors: Goswami Binita , Mahajan Rajiv , Jain Anju , Koner Bidhan Chandra 
Published: September 2021

Objectives:
The present study was conducted to evaluate the effect of Team Idea Mapping (TIM) sessions on the problem solving skills of postgraduate (PG) students of Biochemistry, as deduced from retro-pre self-efficacy questionnaire.

Materials and Methods:
The study was conducted enrolling students pursuing PG-MD course in Medical Biochemistry in a premier medical college. First TIM session was preceded by sensitization of PG students and departmental faculty. In total, four TIM sessions were conducted. Retro-pre self efficacy questionnaire was administered 3 months after the last session. Feedback from the students was collected immediately after last session and satisfaction index was also calculated.

Results:
The satisfaction index was highest (100) for items stating that TIM sessions promoted interactivity and participatory behaviorand lowest (78) for item stating that TIM sessions promoted reflective behavior respectively. The students expressed enhanced self-efficacy in understanding Biochemistry concepts, clinical application of Biochemistry, problem solving skills in Biochemistry, interpreting laboratory reports, participation in group works and clarifying problems with peers and seniors. However, the sessions were not as effective in instilling technical skills like trouble shooting for analyzer breakdowns.

Conclusion:
TIM is an effective tool for instilling problem solving skills in medical PG students, additionally fortifying their attitude to work in groups.
Possibilities of the indocyanine green dye application for evaluation of peculiarities of lymph outflow and metastasizing of colorectal cancer
Authors: Grubnik V. V. , Nikitenko R. P. , Mishchenko V. V. , Ilyashenko V. V. , Degtyarenko S. P. , Parfentiev R. S. , Kvasha A. N. 
Published: September 2021

Objective. Studying of velocity of prevalence of luminescent dye indocyanine green along lymphatic vessels in the large bowel surgery.
Materials and methods. Estimation of procedure for coloring of tumoral substrate and lymphatic vessels while performance of oncological operations was conducted. We performed laparoscopic resection of sigmoid colon in 7 patients, suffering tumors, and anterior rectal resection in 5 patients, having tumors of upper ampullary part of rectum, using indocyanine green dye.
Results. In Group I, consisting of 7 patients, surgical technique of no touch manipulations on the tumor before transection of feeding vessels (NTIT–operations) was applied, and in Group II, consisting of 5 patients, the tumor mobilization was done primarily. Application of indocyanine green dye helped a lot to establish localization and prevalence of the process in rectum.
Conclusion. Application of fluorescent dye indocyanine green on tumoral substrate before doing ligation of feeding vessels raises possibility of the complication occurrence, consisting of the cancer cells dissemination in abdominal cavity. While performing laparoscopic procedures in resection of the large bowel tumors it is expedient to ligate the feeding vessels primarily, with secondary manipulation– to dissect and mobilize the tumoral substrate.
Prognostic role of levels of extracellular histones H3 for diagnosis of early dysfunction of transplant after hepatic transplantation
Authors: Novruzov N. G. 
Published: September 2021

Objective. The aim of this study was to determine the prognostic role of extracellular histones in the diagnosis of early graft dysfunction after liver transplantation..
Materials and methods. The 93 recipients undergoing LDLT were enrolled in this prospective study. Blood samples of patients were collected on postoperative day 1 and histone levels in the plasma samples were measured with Total Histone H3 sandwich ELISA kits. 19 (20.4%) subjects had early graft dysfunction (EAD) which was diagnosed on postoperative day 7 according to Ol-thoff’s criteria, based on liver function tests and coagulation profiles. Other 74 (79.6%) recipients did not have EGD.
Results. Levels of circulating histones were depressed in patients with EGD (0,808±0.026, 95% (CI) 0.752-0.864) than in patients without EGD (0.820±0.017, 95% (CI) 0.786-0.854) (P=0.727). These differences were not significant. The sources of histones in the circulation are not etiologies specific and levels of total histone H 3 after 24 h of operation had not stronger predictive value with AUC 0.477 (95 % CI 0.329 to 0.625) for liver dysfunction. The AUC value of the total bilirubin (AUC 0.685, 95 % CI 0.546 to 0.825) in predicting early graft dysfunction outperformed other LFTs and was less than CRP (AUC 0.705, CI 0.573 to 0.838).
The optimal cutoff value of total bilirubin obtained from the analysis of ROC curves was 4,5 and surpassed all other parameters with a sensitivity of 94.4% and a specificity of 40.7% respectively for prognoses of EGD (P=0.012). The univariate analysis determined that postoperative neutrophils level and CRP were identified as independent risk factors for early graft dysfunction. Neutrophils had a higher predictive value for liver dysfunction than any other parameter within 24 h (Odds ratio (OR) 16.3; 95% CI: 1.7-156.3, P = 0.016).
Conclusion. Collectively, extracellular histone H3 levels were depressed, total bilirubin and CRP levels were elevated in patients with EGD, which can be used as early predictors for liver tissue damage and early allograft dysfunction in patients after liver transplantation.
Effect Isolation and identification of Listeria monocytogenes from aborted women with studing of its pathogenic
Authors: Abdalla M. S. , AL-Khatib G. M. , Alwan M. J. 
Published: September 2021

The isolation and identification of the bacterium L.monocytogenes among abortion in pregnant women were investigated in this research. One hundred and fifty samples including placental tissue and maternal blood were randomly collected from cases of abortion from AL-Habibia Teaching Hospital and AL-Yarmuk Teaching Hospital. These samples were taken from patients in 16 - 45 years of age. Listeria monocytogenes was isolated from three cases only, two of them
from AL-Habibia Teaching Hospital ,while the other one from AL-yarmuk Teaching Hospital. Their gestational age were 22 , 24 , and 28 weeks. Bacterial isolation was done by using routin and specific culture media and two methods for enrichment were preformed.
The biological and biochemical properties of the isolates as well as the pathogenicity of L.monocytogenes in mice were described in the original paper. Infected mice were died after 2 - 5 days post inoculation. The histopathological changes were acute suppurative inflammation in the begining « later on chronic granulomatous reaction were developed , within internal organs
The Risk of Perioperative Bleeding in Patients with Dual Antiplatelet Therapy
Authors: Domanskyy Taras M. , Gabriyelyan Artur V. , Beregovoy Oleg V. , Filianin Stanislav I. , Moshta Svitlana S. 
Published: September 2021

Background. Patients with dual antiplatelet therapy have high risk of perioperative bleeding. In this article we evaluated the risk of bleeding in patients whose antiplatelet therapy had not been canceled before coronary artery bypass grafting (CABG).
The aim. To investigate and evaluate the risk of intra- and postoperative bleeding in patients who underwent CABG during antiplatelet therapy.
Materials and methods. In the study, 47 case reports of patients with coronary heart disease who underwent CABG were evaluated. The patients were divided into 2 groups. The first group included 26 patients who discontinued antiplatelet therapy less than 5 days before the operation. The second group included 21 patients who discontinued antiplatelet therapy more than 5 days before the operation. Stratification of the risk of bleeding was performed using HAS-BLED Score for Major Bleeding Risk online calculator.
Results and discussion. The major bleeding risk was 5.1 ± 1.4% and 4.4 ± 1.6% in the first and in the second group, respectively. In spite of higher risk of bleeding in the first group, there was no significant difference in intra- and postoperative bleeding complications.
Conclusions. Candidates for surgical intervention who receive dual antiplatelet therapy have high risk of intra- and postoperative bleeding complications. In urgent cases when timely discontinuation of dual antiplatelet therapy is impossible and there is urgent need in the intervention, the latter must be performed. For patients who were prepared for CABG and discontinued dual antiplatelet therapy less than 5 days before the operation, sufficient volume of blood for transfusion must be provided.
Penyuluhan Kesehatan tentang Pentingnya Deteksi Dini Kanker Payudara dan Praktik Pemeriksaan Payudara Sendiri pada Remaja Putri melalui Zoominar
Authors: Novelia Shinta , Carolin Bunga Tiara 
Published: September 2021

Pemeriksaan payudara sendiri atau SADARI hingga saat ini merupakan cara deteksi dini kanker payudara yang cukup efektif. SADARI mudah dilakukan dan bisa diterapkan kepada semua usia, baik remaja dan wanita dewasa. Dengan melakukan SADARI yang benar dan rutin, sebanyak 80 persen kanker payudara bisa ditemukan. Meski gerakan sangat mudah, nyatanya belum banyak wanita yang tergerak untuk melakukan SADARI. Penyuluhan deteksi dini kanker payudara dengan SADARI dilakukan dengan metode ceramah, demonstrasi dan praktik. Penyuluhan kesehatan terlaksana dengan baik. Sebagian besar peserta mengaku tidak mengerti tentang gejala kanker payudara dan mereka mengakui bahwa kegiatan ini memberikan banyak manfaat bagi mereka.
Upaya Pencegahan Seks Bebas dan Pemahaman Reproduksi Sehat pada Remaja
Authors: Ningsih Eka Sarofah , Susila Ida , Safitri Oktavia Dian 
Published: September 2021

Remaja wajib tahu tentang kesehatan reproduksi sehat agar memiliki memiliki infromasi yang benar mengenai proses reproduksi serta berbagai faktor masalah yang terjadi. Tujuan pendidikan kesehatan reproduksi pada remaja yaitu remaja bisa mengetahui pentingnya kesehatan reproduksi remaja pada masa pubertas. dampak negatif, mengetahui berbagai penyakit pada alat reproduksi serta bisa menjaga kebersihan dan kesehatan diri sendiri. Dengan mendapat informasi yang benar, diharapkan remaja memiliki sikap dan tingkah laku yang bertanggung jawab dalam proses reproduksi sehat. Metode pada pengabdian masyarakat saat ini yang digunakan adalah ceramah, diskusi dan tanya jawab. Hasil penelitian menunjukan bahwa: (1) Pemberian pemahaman kepada orang tua untuk mengatasi masalah seks bebas pada remaja (2) Upaya pencegahan seks bebas dengan pemahaman pendidikan kesehatan reproduksi serta dampak penyakit yang ditimbulkan (3) Usaha pencegahan dalam menanggulangi problema seksualitas remaja (4) Layanan informasi dalam aplikasi tentang pemahaman reproduksi sehat pada remaja.
Upaya Peningkatan Status Gizi Ibu Hamil di Masa Pandemi Covid-19 melalui Program Penyuluhan Rawat Jalan (PENYU RAJA) di Puskesmas Mojosari Kecamatan Mojosari Kabupaten Mojokerto
Authors: Hety Dyah Siwi , Susanti Ika Yuni , Anggreni Dhonna 
Published: September 2021

Kehamilan merupakan masa kritis di mana gizi ibu yang baik adalah faktor penting yang mempengaruhi kesehatan ibu dan anak. Masa kehamilan merupakan salah satu masa kritis tumbuh-kembang manusia yang singkat (window of opportunity). Kekurangan gizi yang terjadi di masa tersebut akan menimbulkan kerusakan awal pada kesehatan, perkembangan otak, kecerdasan, kemampuan sekolah, dan daya produksi yang bersifat menetap, tidak dapat diperbaiki. Salah satu upaya yang diharapkan dapat mendukung upaya peningkatan gizi pada ibu hamil, adalah dengan melaksanakan penyuluhan kesehatan tentang gizi ibu hamil melalui Antenatal Care (ANC) Terpadu. Pelayanan ANC Terpadu di batasi hanya hari selasa saja, tidak seperti sebelum ada pandemic covid-19 setiap hari selasa dan rabu. Hal ini untuk antisipasi penyebaran virus covid-19 di Puskesmas Mojosari.Tujuan Pengabmas ini adalah adanya peningkatan pemahaman, sikap serta perilaku ibu hamil tentang pentingnya kebutuhan gizi ibu hamil di masa pandemic Covid-19.
Pertemuan penyuluhan rawat jalan ini dilakukan 4-5 kali pertemuan pada ibu hamil yaitu pemberian materi tentang Gizi Ibu Hamil di masa pandemi Covid-19. Setelah pemberian materi di lanjutkan evaluasi. Evaluasi dilakukan sebanyak kurang lebih 2-3 kali untuk melihat kesesuaian dengan hasil kesepakatan fasilitator dengan peserta. Waktu pertemuan disesuaikan dengan jadwal ANC terpadu di Puskesmas Mojosari, yaitu setiap hari selasa.
Keberhasilan dari program ini di harapkan ibu hamil secara bersama-sama terus berkesinambungan serta selalu berdiskusi, tukar pendapat, tukar pengalaman akan pemenuhan pelayanan kesehatan ibu hamil khususnya tentang pentingnya kebutuhan gizi ibu hamil di masa pandemi Covid-19 yang telah dibimbing oleh fasilitator.