bluuebunny/crossref_metadata_2025_split huggingface dataset:
A scoping review of patient engagement activities during COVID-19: More consultation, less partnership
Authors: Cadel Lauren , Marcinow Michelle , Sandercock Jane , Dowedoff Penny , Guilcher Sara J. T. , Maybee Alies , Law Susan , Kuluski Kerry 
Published: September 2021

Background
The COVID-19 pandemic has had a devastating impact on healthcare systems and care delivery, changing the context for patient and family engagement activities. Given the critical contribution of such activities in achieving health system quality goals, we undertook to address the question: What is known about work that has been done on patient engagement activities during the pandemic?

Objective
To examine peer-reviewed and grey literature to identify the range of patient engagement activities, broadly defined (inclusive of engagement to support clinical care to partnerships in decision-making), occurring within health systems internationally during the first six months of the COVID-19 pandemic, as well as key barriers and facilitators for sustaining patient engagement activities during the pandemic.

Methods
The following databases were searched: Medline, Embase and LitCOVID; a search for grey literature focused on the websites of professional organizations. Articles were required to be specific to COVID-19, describe patient engagement activities, involve a healthcare organization and be published from March 2020 to September 2020. Data were extracted and managed using Microsoft Excel. A content analysis of findings was conducted.

Results
Twenty-nine articles were included. Few examples of more genuine partnership with patients were identified (such as co-design and organizational level decision making); most activities related to clinical level interactions (e.g. virtual consultations, remote appointments, family visits using technology and community outreach). Technology was leveraged in almost all reported studies to interact or connect with patients and families. Five main descriptive categories were identified: (1) Engagement through Virtual Care; (2) Engagement through Other Technology; (3) Engagement for Service Improvements/ Recommendations; (4) Factors Impacting Patient Engagement; and (5) Lessons Learned though Patient Engagement.

Conclusions
Evidence of how healthcare systems and organizations stayed connected to patients and families during the pandemic was identified; the majority of activities involved direct care consultations via technology. Since this review was conducted over the first six months of the pandemic, more work is needed to unpack the spectrum of patient engagement activities, including how they may evolve over time and to explore the barriers and facilitators for sustaining activities during major disruptions like pandemics.
What do malaria program officers want to learn? A survey of perspectives on a proposed malaria short course in Nigeria
Authors: Ajumobi Olufemi , Afolabi Rotimi Felix , Adewole Adefisoye , Balogun Muhammad Shakir , Nguku Patrick , Ajayi IkeOluwapo O. 
Published: September 2021

Background
In disease control, the program officers are vital to the successful implementation of control strategies. However, poor knowledge of the disease and its control, staff attrition, and lack of intentional training for new staff can lead to under-performance and ineffectiveness of interventions. Thus, the Nigeria Field Epidemiology and Laboratory Training Program, in collaboration with National Malaria Elimination Program, planned a malaria short course (MSC) to strengthen the capacity of current program managers and incoming staff. To guide the development of the curriculum for the MSC, we conducted a needs assessment survey to ascertain the perceived usefulness of the MSC, the priority rating of MSC thematic domains and associated factors.

Methods
Overall, 384 purposively selected respondents across ten states and the Federal Capital Territory in Nigeria were interviewed. These comprised malaria and non-malaria control program staff at state, local government area (LGA) and ward levels. We administered a structured questionnaire to elicit information on socio-demographics, training needs, priority malaria thematic domains, perceived course usefulness and willingness of ministries/organizations to release staff to attend the MSC. Data were analyzed using descriptive and inferential statistics at p<0.05.

Results
Mean age was 43.9 (standard deviation: 7.6 years), 172 (44.8%) were females. Of the 384 respondents, 181 (47.1%), 144 (37.5%) and 59 (15.4%) were at the ward, LGA and state levels, respectively. Seventy-two (18.8%) had never worked in malaria control program. Majority (98.7%, n = 379) reported the need for further training, 382 (99.5%) opined that the course would be useful, and all affirmed their employers’ willingness towards their participation at the training. Respondents rated high the domains of basic malariology, malaria treatment, malaria prevention, surveillance/data management, use of computers, leadership skills, program management and basic statistics. Predictors of malaria topical domains’ high rating were gender (odds ratio (OR) = 6.77; 95% CI:3.55–12.93) and educational qualifications (OR = 0.48; 95% CI:0.26–0.89).

Conclusions
A malaria short course is a necessity and appropriate for program officers at different levels of health administration in Nigeria to achieve malaria elimination, taking into consideration the challenges of human resource retention. The outcome of this study should inform the curriculum and the delivery of the MSC.
There Is More Than Meets the Eye: Success Stories of a Visual Impaired Student and Lecturer
Authors: Delport Danri Hester 
Published: September 2021

Although Higher Education Institutions have come a long way in including students with disabilities, many students still experience exclusion or "otherness" among their abled peers. Currently, there is a gap in research where the focus is on the abilities and success stories of such individuals rather than their disabilities, the barriers they face, or the adjustments made to meet their needs. This research aims to share the success stories of a visually impaired student and his visually impaired lecturer at a South African University. Semi-structured, in-depth individual interviews were used as collection instruments where after the data was analyzed. The appreciation for friends outweighed the physical barriers. Through perseverance and hard work, the disabled student proved her teacher wrong by successfully entering university and completing her Ph.D.. Both participants looked beyond their limitations and realized their capabilities.[Meskipun usaha untuk mewujudkan perguruan tinggi inklusif sudah dilakukan sejauh ini, tetapi banyak mahasiswa difabel yang masih merasakan ‘keberbedaan’ dirinya dari mahasiswa lain. Inklusi penyandang disabilitas harus mengarah pada peningkatan partisipasi dalam tatanan yang menghasilkan siswa, teman, atau guru terbaik. Saat ini, ada kesenjangan dalam penelitian yang fokusnya adalah pada kemampuan dan kisah sukses individu tersebut daripada disabilitas mereka, hambatan yang mereka hadapi, atau penyesuaian yang dilakukan untuk memenuhi kebutuhan mereka. Penelitian ini bertujuan untuk berbagi kisah sukses seorang mahasiswa tunanetra sekaligus dosen tunanetranya di Universitas Afrika Selatan. Melalui ketekunan dan kerja keras, para difabel dalam tulisan ini membuktikan apa yang dianggap tidak mungkin. Kedua subyek melampaui keterbatasan mereka dan menyadari kemampuan mereka.]
Aberrant expression of PI3K/AKT signaling is involved in apoptosis resistance of hepatocellular carcinoma
Authors: Wang Zhuangqiang , Cui Xiaopeng , Hao Gaopeng , He Jiefeng 
Published: September 2021

Abstract
Phosphatidylinositol 3-kinase (PI3K)/AKT signaling is a crucial pathway for cell survival and proliferation, which are regulated by several growth factors and activated receptors. Upregulated PI3K/AKT signaling molecules were reported in several cancers and they are associated with altered cellular functions, leading to oncogenesis. Here, we have examined the implications of elevated PI3K/AKT expression in the apoptosis resistance of human hepatocellular carcinoma (HCC) Huh7 cells. We showed that PI3K/AKT signaling is significantly upregulated in Huh7 cells by quantitative polymerase chain reaction and protein expression analysis. Also, perversely upregulated PI3K/AKT signaling Huh7 cells are highly resistant to treatment with chemotherapy drugs (docetaxel and sorafenib) and acquired apoptosis resistance through downregulation of tumor suppressor protein PTEN (phosphatase and tensin homolog deleted on chromosome ten). Hence, we have investigated the effect of PTEN overexpression on apoptosis induction in Huh7 cells. We showed that PTEN overexpressed Huh7 cells became more sensitive toward the aforesaid drugs and induced apoptotic cell death due to intracellular reactive oxygen species (ROS) generation. Concurrently, the overexpression of PTEN leads to the activation of mitochondria facilitated intrinsic apoptosis, evidenced by upregulated cytochrome C, caspase 3, and caspase 9. Collectively, our data suggest that the aberrant expression of PI3K/AKT signaling contributes to apoptosis resistance in HCC.
Production of a homogeneous seismic catalog based on machine learning for northeast Egypt
Authors: Moustafa Sayed S. R. , Mohamed Gad-Elkareem A. , Metwaly Mohamed 
Published: September 2021

Abstract
This research presents a new approach which addresses the conversion of earthquake magnitude as a supervised machine-learning problem through a multistage approach. First, the moment magnitude (M
w) calculations were extended to lower magnitude earthquakes using the spectral P-wave analyses of the vertical component seismograms to improve the scaling relation of M
w and the local magnitude (M
L) of 138 earthquakes in northeastern Egypt. Second, using unsupervised clustering and regression analysis, we applied the k-means clustering technique to subdivide the mapped area into multiple seismic activity zones. This clustering phase created five spatially close seismic areas for training regression algorithms. Supervised regression analysis of each seismic area was simpler and more accurate. Conversion relations between M
w and M
L were calculated by linear regression, general orthogonal regression (GOR), and random sample consensus (RANSAC) regression techniques. RANSAC and GOR produced better results than linear regression, which provides evidence for the effects of outliers on regression accuracy. Moreover, the overall multistage hybrid approach produced substantial improvements in the measured-predicted dataset residuals when individual seismic zones rather than all datasets were considered. In 90% of the analyzed cases, M
w values could be regarded as M
L values within 0.2 magnitude units. Moreover, predicted magnitude conversion relations in the current study corresponded well to magnitude conversion relations in other seismogenic areas of Egypt.
The antioxidant Rutin counteracts the pathological impact of α-synuclein on the enteric nervous system in vitro
Authors: Christmann Anne , Gries Manuela , Scholz Patrik , Stahr Pascal L. , Law Jessica Ka Yan , Schulte Steven , Martin Monika , Lilischkis Rainer , Ingebrandt Sven , Keck Cornelia M. , Schäfer Karl-Herbert 
Published: September 2021

Abstract
Motoric disturbances in Parkinson’s disease (PD) derive from the loss of dopaminergic neurons in the substantia nigra. Intestinal dysfunctions often appear long before manifestation of neuronal symptoms, suggesting a strong correlation between gut and brain in PD. Oxidative stress is a key player in neurodegeneration causing neuronal cell death. Using natural antioxidative flavonoids like Rutin, might provide intervening strategies to improve PD pathogenesis. To explore the potential effects of micro (mRutin) compared to nano Rutin (nRutin) upon the brain and the gut during PD, its neuroprotective effects were assessed using an in vitro PD model. Our results demonstrated that Rutin inhibited the neurotoxicity induced by A53T α-synuclein (Syn) administration by decreasing oxidized lipids and increasing cell viability in both, mesencephalic and enteric cells. For enteric cells, neurite outgrowth, number of synaptic vesicles, and tyrosine hydroxylase positive cells were significantly reduced when treated with Syn. This could be reversed by the addition of Rutin. nRutin revealed a more pronounced result in all experiments. In conclusion, our study shows that Rutin, especially the nanocrystals, are promising natural compounds to protect neurons from cell death and oxidative stress during PD. Early intake of Rutin may provide a realizable option to prevent or slow PD pathogenesis.
Unmanned aerial vehicle evasion manoeuvres from enemy aircraft attack
Authors: Evdokimenkov Veniamin N. , Kozorez Dmitriy A. , Rabinskiy Lev N. 
Published: September 2021

Abstract
One of the most important problems associated with the combat use of unmanned aerial vehicles remains to ensure their high survivability in conditions of deliberate countermeasures, the source of which can be both ground-based air defence systems and fighter aircraft. For this reason, the study and optimization of evasive manoeuvres of an unmanned aerial vehicle from an enemy aircraft attack remains relevant. Based on the game approach, the authors of this paper propose an algorithm for guaranteeing control of the trajectory of an unmanned aerial vehicle, which ensures its evasion from an enemy air attack. The study of the influence of tactically significant indicators of the manoeuvrability of an unmanned aerial vehicle on the effectiveness of the evasion manoeuvre was carried out. The model predictions are presented, reflecting the degree of influence of unmanned aerial vehicle manoeuvring capabilities on achieving a positional advantage when solving the problem of evading air enemy attack.
Placental findings in singleton stillbirths: a case-control study from a tertiary-care center in India
Authors: Tiwari Purnima , Gupta Madhavi M. , Jain Shyama Lata 
Published: September 2021

Abstract

Objectives
Placental examination in a case of stillbirth can provide insight into causative/associated factors with fetal demise. The aim of this study was to compare placental and umbilical cord pathologies in singleton stillbirth and livebirth placentas, and to find prevalence of various associated maternal and fetal clinical factors.

Methods
This case-control study was conducted at a tertiary-care center in India over a period of 20 months. About 250 women who delivered stillborn fetus ≥28 weeks’ gestation and 250 maternal-age-matched controls were recruited. Sociodemographic and clinical details were noted and placental gross and microscopic examination was done. Placental findings were compared between stillbirth and livebirth (overall), preterm stillbirth and preterm livebirth as well as term stillbirth and term livebirth in six categories – placenta gross, cord gross, membranes gross, maternal vascular malperfusion, fetal vascular malperfusion and inflammatory response. Prevalence of 11 maternal and fetal factors were studied in all categories of placental findings in both livebirth and stillbirth.

Results
Placental findings in all six categories were significantly associated with stillbirths (p<0.05). The placental findings associated with stillbirth with highest odds included placental hypoplasia (OR 9.77, 95% CI 5.46–17.46), necrotizing chorioamnionitis (OR 9.30, 95% CI 1.17–73.96) and avascular villi (OR 8.45, 95% CI 3.53–20.25). More than half of the women with stillbirths had medical disorders (n=130, 52.0%) and the most prevalent was hypertensive disorder (n=45, 18.0%).

Conclusions
Changes in placenta are associated with development of stillbirth. Therefore, antenatal investigations to identify placental dysfunction should be investigated to determine whether these reduce stillbirth. Also, placental examination in a case of stillbirth can detect/diagnose many maternal/fetal conditions and thereby can help in preventing future stillbirths.
Innovación Tecno-Educativa “Google”. Plataformas Digitales, Datos y Formación Docente
Authors: Saura Geo , Díez Gutiérrez Enrique Javier , Rivera Vargas Pablo 
Published: September 2021

Las plataformas digitales están generando los avances más significativos en la innovación educativa global. La pandemia mundial de Covid-19 está acelerando la expansión de las plataformas digitales en educación. Google es la corporación tecnológica que, a través de Google for Education, está liderando la innovación educativa mediante sus plataformas digitales. A partir de este contexto, el objetivo del presente artículo es analizar la innovación en las prácticas educativas y en la formación del profesorado, a través de las plataformas digitales de Google. Desde un enfoque cualitativo basado en la implementación de una etnografía digital y una tecnografía, se han analizado en profundidad ocho sitios web de Google que tienen relación con la formación docente y los datos. Los resultados del estudio muestran que, a través de la API de Classroom, se están generando (1) nuevos procesos de control tecno-educativo, (2) nuevas dinámicas extractivas de los datos y (3) nuevas relaciones rentistas con la industria tecnológica. Junto a ello, se observa que la formación docente para la innovación tecno-educativa en Google se basa en un desarrollado profesional piramidal mediante certificaciones docentes, y en “comunidades educativas Google” que se auto-forman y expanden las herramientas y las lógicas de mercado de la corporación tecnológica.
The stock market as a casino: Associations between stock market trading frequency and problem gambling
Authors: Mosenhauer Moritz , Newall Philip W. S. , Walasek Lukasz 
Published: September 2021

Abstract

Background and aims
Personal investors decrease their stock market investment returns by trading frequently, which the behavioral finance literature has primarily explained via investors' overconfidence and low levels of financial literacy. This study investigates whether problem gambling can help account for frequent trading in a sample of active gambler/investors, as suggestive of frequent trading being in part driven by a behavioral addiction to gambling-like activities.

Methods
A retrospective cross-sectional study of 795 US-based participants, who reported both being active gamblers and holding stock market investments. Recollected stock trading activity (typical portfolio size, purchases and sales of stocks) was compared with scores on the Problem Gambling Severity Index, a financial literacy scale, and a measure of overconfidence.

Results
Self-reported relative stock portfolio turnover was positively associated with problem gambling scores. This association was robust to controls for financial literacy, overconfidence, and demographics, and occurred equally among investors of all self-reported portfolio sizes.

Discussion and conclusions
This study provides support for the hypothesis that behavioral addiction to gambling-like activities is associated with frequent stock market trading. New investment products that increase the ease of trading may therefore be detrimental to some investors.
Marketing territorial una herramienta estratégica para el sector rural: Revisión bibliográfica
Authors: Burgos-Cañas Dario , Fonseca-Pinto Dora Esther , Fonseca-Pinto Carlos Arturo 
Published: September 2021

El presente artículo de revisión se basa en un estudio bibliográfico en el que se busca seleccionar analizar y sintetizar la literatura científicas sobre el marketing territorial como parte fundamental y estructural para el desarrollo del proyecto de investigación “Marketing territorial: una estrategia de desarrollo sostenible para las comunidades del corredor del roble en el municipio de Sotaquirá”, la revisión bibliográfica es de tipo documental de carácter científico, apoyada por las bases de datos como Scielo, Scopus, Dialnet, lens y el buscador de Google Académico, con un rango de búsqueda no menor a 5 años. Como resultados se evidencia que el marketing territorial ha generado las herramientas necesarias para ser utilizado como una estrategia de desarrollo social, económico, cultural y ambiental.
Winter Diet of an Eurasian Eagle Owl (Bubo bubo) Near the Yedikır Dam, Amasya (Turkey)
Authors: ÖZKOÇ Ömral Ünsal , SELÇUK Ahmet Yesari 
Published: September 2021

Abstract
Aim of study: The aim of this study was to contribute to the data on the diet of Eurasian Eagle Owl (Bubo bubo) in Turkey.
Area of study: This study was conducted near the Yedikır Dam (Amasya)
Material and methods: A total of 12 pellets of the Eurasian Eagle Owl collected in Yedikır Dam was analyzed. The remains of the skull and lower jaw were used for the identification of mammals.
Main results: 60 preys were identified to belong to 6 different taxa (5 Rodents and 1 Passerine). The main prey was Mus spp. (35.0%). Only one bird remain was recorded from pellets.
Highlights: Pellet analyses were the first step for understanding the diet of B. bubo. Considering, B. bubo is an opportunistic predator and can consume medium-sized mammals and large-sized birds. Hence, a diet study supported with remains that are directly collected from the nest or perching site and their surroundings will reveal more objectively prey preferences for this apex predator.
Morphological Traits of Silver Fir (Abies alba Mill.) in the Bosnian-Herzegovinian Provenance Test
Authors: HODZIC Mirzeta Memisevic , HALILOVIC Velid , ADVAGIC Admir , BALLIAN Dalibor 
Published: September 2021

Abstract
Aim of study: This research aims to determine if there are statistically significant differences among provenances of silver fir (Abies alba Mill.) as one of the most important tree species in Bosnia and Herzegovina, to choose a provenance with the best productivity for further silvicultural activities of silver fir in the country.
Material and methods: The height and diameter at breast height were measured, and the basal area and volume of silver fir trees were calculated in the silver fir provenance test. The test contains nine provenances from Bosnia and Hezegovina and was launched in 1991, with 5-year-old seedlings (3+2). The data were collected in 2013.
Main results: Variance analysis for all traits showed statistically significant differences among provenances. Average breast height diameter in 27-year-old plants for all provenances amounted to 11.0 cm, average height 8.4 m, average basal area 0.010342 m2, and average volume 0.070845 m3
Highlights: The research results confirmed the existence of variability among silver fir provenances in Bosnia and Herzegovina, considering the morphological indicators. Provenance Bosanski Petrovac showed the highest values of all traits, which implies it is the best provenance for the further activities on seed collecting and producing planting material for afforestation in Bosnia and Herzegovina.
The Effects of Cold Stratification, Cold Storage and Gibberellic acid (GA3) on Seed Germination of Bilberry (Vaccinium myrtillus L.)
Authors: BİLGİN Serap , ALIM Esra 
Published: September 2021

Abstract
Aim of study: The effects of cold stratification, cold storage and gibberellic acid (GA3) on seed germination of bilberry (Vaccinium myrtillus L.) were investigated.
Area of study: Ripe berries of V.myrtillus were collected from the Kaz Mountains (İda Mount) National Park-Balıkesir province in Turkey.
Material and methods: In the study five levels of cold moist stratification period, cold dry storage period (control, 15, 30, 60, 90 days) at +4 ºC and three dose of GA3 (control, 500, 1000, 1500 mg/L) treatments were applied. Data were tested independently by ANOVA according to three factors with three replications. 50 seeds were used for each treatment for each replication.
Main results: Cold stratifications, cold storage and GA3 treatments did not increase the germination percentage of bilberry seeds. Germination was found between 23-40% in all experiments.
Highlights: Different pretreatments are advised for increasing germination percentage of V. myrtillus L. seeds