bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of spontaneous resolution of umbilical hernia in children
Authors: Kaur Manvinder , Grandpierre Viviane , Oltean Irina , Weir Arielle , Nasr Ahmed 
Published: June 2021

ObjectiveThe aims were to describe the management of umbilical hernias, to define postoperative complications, and to identify the characteristics of patients that were more likely to have spontaneous resolution of their hernia.MethodsAll patients referred for umbilical hernia at the Children’s Hospital of Eastern Ontario from January 1990 to April 2017 were examined via retrospective chart review. Spontaneous resolution of umbilical hernia was examined using binary logistic regression.ResultsWe included 2621 patients presenting with an umbilical hernia. A total of 1587 (60.5%) patients underwent surgical repair at a median age of 3.6 years (IQR 2.3–5.4). Surgical complications consisted of infection (n=3), bleeding (n=3), hematoma (n=3), and anesthesia-related complications (n=3). For every one-unit increase in defect size, the odds of a spontaneous resolution of the hernia were 5% lower while controlling for prematurity and the presence of comorbidities [adjusted odds ratio (aOR)=0.95; 95% confidence intervel (CI) 0.93 to 0.97]. Premature babies were 80% less likely to experience hernia resolution compared with non-premature babies (aOR=0.20; 95% CI 0.03 to 0.74).ConclusionThe odds of spontaneous resolution were lower for premature babies and were negatively correlated with defect size.
Weak decays of bottom-charm baryons: $$\mathcal {B}_{bc}\rightarrow \mathcal {B}_bP$$
Authors: Han Jia-Jie , Zhang Rui-Xiang , Jiang Hua-Yu , Xiao Zhen-Jun , Yu Fu-Sheng 
Published: June 2021

AbstractAfter the discovery of the double-charm baryon $$\Xi _{cc}^{++}$$

Ξ

cc

+
+

by LHCb, one of the most important topics is to search for the bottom-charm baryons which contain a b quark, a c quark and a light quark. In this work, we study the two-body non-leptonic weak decays of a bottom-charm baryon into a spin-1/2 bottomed baryon and a light pseudoscalar meson with the short-distance contributions calculated under the factorization hypothesis and the long-distance contributions considering the final-state-interaction effects. The branching fractions of all fifty-seven decay channels are estimated. The results indicate that $$\Xi _{bc}^+\rightarrow \Xi _b^0\pi ^+$$

Ξ

bc

+

→

Ξ
b
0

π
+

, $$\Xi _{bc}^{0}\rightarrow \Xi _{b}^{-}\pi ^+$$

Ξ

bc

0

→

Ξ

b

-

π
+

and $$\Omega _{bc}^0\rightarrow \Omega _b^-\pi ^+$$

Ω

bc

0

→

Ω
b
-

π
+

decay modes have relatively large decay rates and thus could be used to experimentally search for the bottom-charm baryons. The topological diagrams and the SU(3) symmetry of bottom-charm baryon decays are discussed.
Pacing of late Pliensbachian and early Toarcian carbon cycle perturbations and environmental change in the westernmost Tethys (La Cerradura Section, Subbetic zone of the Betic Cordillera, Spain)
Authors: Silva Ricardo L. , Ruhl Micha , Barry Cillian , Reolid Matías , Ruebsam Wolfgang 
Published: June 2021

Abstract

Detailed assessment of high-resolution elemental and isotopic geochemical datasets collected from the marl–limestone alternations cropping out at La Cerradura (Subbetic domain of the Betic Cordillera, Spain) and chrono- and chemostratigraphic correlation with the reference Mochras borehole (Cardigan Bay Basin, UK) unveiled valuable new insights into understanding of late Pliensbachian–early Toarcian palaeoenvironmental dynamics in a key geographical area between the northern European seaway and the Tethys Ocean. This study shows that deposition in the study area took place under dominantly oxic water column conditions, indicated, for example, by the generalized lack of enrichment in organic matter and redox metals typically associated with anoxia and euxinia. Carbon isotope stratigraphy (δ
13
C
TOC
) allowed recognition of the
spinatum
(=
emaciatum
in the Submediterranean Province), Pliensbachian–Toarcian, and early Toarcian Oceanic Anoxic Event negative carbon isotopic excursions and the late Pliensbachian positive carbon isotopic excursion. It is here suggested that the observed periodic changes in lithology and sedimentary geochemistry occur at orbital frequencies (i.e. long and short eccentricity and, tentatively, precession), hinting at an astronomical control of the local–regional climate and environment during the Pliensbachian and Toarcian in the mid- to low-latitude South Iberian palaeomargin area.
Kaposi Sarcoma Incidence, Burden, and Prevalence in United States People with HIV, 2000–2015
Authors: Peprah Sally , Engels Eric A. , Horner Marie-Josèphe , Monterosso Analise , Hall H. Irene , Johnson Anna Satcher , Pfeiffer Ruth M. , Shiels Meredith S. 
Published: June 2021

Abstract

Background:
The introduction of combination antiretroviral therapy (cART) has led to a significant reduction in Kaposi sarcoma (KS) incidence among people with HIV (PWH). However, it is unclear if incidence has declined similarly across key demographic and HIV transmission groups and the annual number of incident and prevalent KS cases remains unquantified.

Methods:
Using population-based registry linkage data, we evaluated temporal trends in KS incidence using adjusted Poisson regression. Incidence and prevalence estimates were applied to CDC HIV surveillance data, to obtain the number of incident (2008–2015) and prevalent (2015) cases in the United States.

Results:
Among PWH, KS rates were elevated 521-fold [95% confidence intervals (CI), 498–536] compared with the general population and declined from 109 per 100,000 person-years in 2000 to 47 per 100,000 person-years in 2015, at an annual percentage change of −6%. Rates declined substantially (Ptrend &lt; 0.005) across all demographic and HIV transmission groups. Of the 5,306 new cases estimated between 2008 and 2015, 89% occurred among men who have sex with men. At the end of 2015, 1,904 PWH (0.20%) had been diagnosed with KS in the previous 5 years.

Conclusions:
A consistent gradual decline in KS incidence has occurred among PWH in the United States during the current cART era. This decrease is uniform across key demographic and HIV transmission groups, though rates remain elevated relative to the general population.

Impact:
Continued efforts to control HIV through early cART initiation and retention in care need to be maintained and possibly expanded to sustain declines.
The Design of Firms: Part 2 - Competitive Advantage
Authors: Dong Andy , Kleinsmann Maaike , Snelders Dirk 
Published: June 2021

Abstract
One of the essential aspects of a company's design is its source of competitive advantage. Extrapolating from Raymond Loewy's famous design strategy acronym, MAYA—the Most Advanced Yet Acceptable Principle—and treating the firm as the object of design, this article explains the competitive advantage of firms from a design perspective. Our design-based recommendation for the competitive advantage of firms is to focus on shaping heterogeneity-based advantages of the firm in ways its paying customers would deem valuable. The novelty and conventionality dynamics of its industry will influence the degree of heterogeneity of the firm. Firms can shape their heterogeneity-based advantages through policies relating to organizational structure, routines, and product portfolio to name a few. Going beyond the role of a design in creating rents above and beyond what other firms can imagine, our claim focuses on the ways in which heterogeneity is a fundamental driver of its competitive advantage. If correct, the design-based view suggests that the ideal level of heterogeneity of the firm relative to current competitive conditions and evolution paths adopted by the firm and its competitors is more fundamental to firm profitability than its resources.
Policy Instrumentation: The Object of Service Design in Policy
Making
Authors: Trippe Helena Polati 
Published: June 2021

Abstract
Service design, as a practice and an area of research, has been at the forefront of the debates surrounding innovation, technology, and organizational change. More recently, service design is deployed as a means to drive public sector efficiency and address the growing complexity of public service delivery. This article examines the application of service design to policy making in order to situate service design at the intersection of research on public services, design, and policy design. Furthermore, it will explore how conceiving of policy instruments as design artifacts might provide a way to think about the object of policy design and government action.
Healthcare workers as a sentinel surveillance population in the early phase of the COVID-19 pandemic
Authors: Venkatachalam Indumathi , Conceicao Edwin Philip , Aung May Kyawt , How Molly Kue Bien , Wee Liang En , Sim Jean Xiang Ying , Tan Ban Hock , Ling Moi Lin 
Published: June 2021

Introduction:
Healthcare workers (HCWs) are a critical resource in the effort to control the COVID-19 pandemic. They are also a sentinel surveillance population whose clinical status reflects the effectiveness of the hospital’s infection prevention measures in the pandemic.

Methods:
This was a retrospective cohort study conducted in Singapore General Hospital (SGH), a 1,822-bed tertiary hospital. Participants were all HCWs working in SGH during the study period. HCW protection measures included clinical workflows and personal protective equipment developed and adapted to minimise the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. HCW monitoring comprised staff contact logs in high-risk locations, twice-daily temperature monitoring, assessment of HCWs with acute respiratory illnesses (ARIs) in the staff clinic and, in the event of an exposure, extensive contact tracing, detailed risk assessment and risk-based interventions. HCW surveillance utilised monitoring data and ARI presentations and outcomes.

Results:
In the ten-week period between 6 January 2020 and 16 March 2020, 333 (17.1%) of 1,946 HCWs at risk of occupational COVID-19 presented with ARI. 32 (9.6%) screened negative for SARS-CoV-2 from throat swabs. Five other HCWs developed COVID-19 attributed to non-clinical exposures. From the nine COVID-19 exposure episodes investigated, 189 HCW contacts were identified, of whom 68 (36.2%) were placed on quarantine and remained well.

Conclusion:
Early in an emerging infectious disease outbreak, close monitoring of frontline HCWs is essential in ascertaining the effectiveness of infection prevention measures. HCWs are at risk of community disease acquisition and should be monitored and managed to prevent onward transmission.
Socrates (AP 14.1[-64])
Authors: Grillo Francesco 
Published: June 2021

Abstract
This article aims to investigate the identity of Socrates, the compiler of AP 14.1-64 (arithmetic problems and riddles). Leaving aside the traditional, but very uncertain, identification with Socrates the epigrammatist (D.L. 2.47), it is shown that the chronological conjecture by Carcopino 1926 (late 1st century BC-2nd century AD) no longer holds. A wider time frame is established (1st-4th centuries AD), although evidence from the (fairly) securely attributable poem (AP 14.1) seems to point to the mid-2nd century AD as the most plausible period of the poet’s activity. It is suggested that Socrates was a Pythagorising Middle Platonist associated with the philosopher Calvenus Taurus, even if his relationship with the Neo-Pythagorean and Middle Platonic traditions remains difficult to define precisely. The article also considers some of the relationships that have been shown to exist between diverging directions in Pythagoreanism (Delatte 1922), offering corrections for future attempts at Quellenforschung.
Knowing of Not-Knowing: the Outlines of a Critical Skepticism
Authors: Binkelmann Christoph 
Published: June 2021

Abstract
Sextus Empiricus’ definition of skepticism as a search for truth still poses great problems for research today. Perhaps the most urgent of these is: How can we reasonably assert the possibility of knowledge and at the same time deny its reality? The paper tries to solve this question by drawing attention to a hitherto neglected variant of skepticism: the so-called critical skepticism. In confrontation with Hume and Kant, Salomon Maimon develops a skeptical position which, with the help of transcendental argumentation, produces a knowing of not-knowing. Maimon defends with Kant (and against Hume) transcendental knowledge which at the same time offers a reason to reject with Hume and against Kant empirical knowledge. By doing so, he distinguishes a knowledge of possibility from a (non-)knowledge of reality, whereby the search for truth—expressed in the assumption that knowledge is possible—is and remains the only truth.
Olmi and Pasolini: Industrialisation, the underdog and ‘ecological eschatology’ in Manon finestra 2 (1956) and Grigio (1957)
Authors: Angeli Silvia 
Published: June 2021

This article focuses on the collaboration between Ermanno Olmi and Pier Paolo Pasolini. Two key figures of the Italian cinematic tradition, Olmi and Pasolini have joined efforts on two occasions, as the Bergamasque director asked Pasolini to provide a commentary for his short films Manon finestra 2 (1956) and Grigio (1957). Two very different products, the two shorts offer a very compelling take on the process of industrialisation taking place in Italy in the 1950s. While Manon presents a slightly more positive view of the transition that Italy has undergone, Grigio is unequivocal in its condemnation, putting forward an alarming thesis: in order for this new society to exist, differences must be erased, communities are to disappear and the least advantaged will be left behind. However, this proposition also has a more optimistic counterpart; namely, the idea that these very communities remain the roots and the true point of reference of our civilisation.
Community-Engaged Needs Assessment of Deaf American Sign Language Users in Florida, 2018
Authors: James Tyler G. , McKee Michael M. , Sullivan Meagan K. , Ashton Glenna , Hardy Stephen J. , Santiago Yary , Phillips David G. , Cheong JeeWon 
Published: June 2021

Objectives Deaf American Sign Language (ASL) users comprise a linguistic and cultural minority group that is understudied and underserved in health education and health care research. We examined differences in health risk behaviors, concerns, and access to health care among Deaf ASL users and hearing English speakers living in Florida. Methods We applied community-engaged research methods to develop and administer the first linguistically accessible and contextually tailored community health needs assessment to Deaf ASL users living in Florida. Deaf ASL users (n = 92) were recruited during a 3-month period in summer 2018 and compared with a subset of data on hearing English speakers from the 2018 Florida Behavioral Risk Factor Surveillance System (n = 12 589). We explored prevalence and adjusted odds of health behavior, including substance use and health care use. Results Mental health was the top health concern among Deaf participants; 15.5% of participants screened as likely having a depressive disorder. Deaf people were 1.8 times more likely than hearing people to engage in binge drinking during the past month. In addition, 37.2% of participants reported being denied an interpreter in a medical facility in the past 12 months. Conclusion This study highlights the need to work with Deaf ASL users to develop context-specific health education and health promotion activities tailored to their linguistic and cultural needs and ensure that they receive accessible health care and health education.
Microfracture Augmentation With Trypsin Pretreatment and Growth Factor–Functionalized Self-assembling Peptide Hydrogel Scaffold in an Equine Model
Authors: Zanotto Gustavo M. , Liesbeny Paul , Barrett Myra , Zlotnick Hannah , Frank Eliot , Grodzinsky Alan J. , Frisbie David D. 
Published: June 2021

Background: Microfracture augmentation can be a cost-effective single-step alternative to current cartilage repair techniques. Trypsin pretreatment combined with a growth factor–functionalized self-assembling KLD hydrogel (“functionalized hydrogel”) has been shown to improve overall cartilage repair and integration to surrounding tissue in small animal models of osteochondral defects. Hypothesis: Microfracture combined with trypsin treatment and a functionalized hydrogel will improve reparative tissue quality and integration as compared with microfracture alone in an equine model. Study Design: Controlled laboratory study. Methods: Bilateral cartilage defects (15-mm diameter) were created on the medial trochlear ridge of the femoropatellar joints in 8 adult horses (16 defects total). One defect was randomly selected to receive the treatment, and the contralateral defect served as the control (microfracture only). Treatment consisted of 2-minute trypsin pretreatment of the surrounding cartilage, subchondral bone microfracture, and functionalized hydrogel premixed with growth factors (platelet-derived growth factor and heparin-binding insulin-like growth factor 1). After surgery, all horses were subjected to standardized controlled exercise on a high-speed treadmill. Clinical evaluation was conducted monthly, and radiographic examinations were performed at 2, 16, 24, 32, 40, and 52 weeks after defect creation. After 12 months, all animals were euthanized. Magnetic resonance imaging, arthroscopy, gross pathologic evaluation of the joint, histology, immunohistochemistry, and biomechanical analyses were performed. Generalized linear mixed models (with horse as random effect) were utilized to assess outcome parameters. When P values were <.05, pairwise comparisons were made using least squares means. Results: Improved functional outcome parameters were observed for the treatment group, even though mildly increased joint effusion and subchondral bone sclerosis were noted on imaging. Microscopically, treatment resulted in improvement of several histologic parameters and overall quality of repaired tissue. Proteoglycan content based on safranin O–fast green staining was also significantly higher in the treated defects. Conclusion: Trypsin treatment combined with functionalized hydrogel resulted in improved microfracture augmentation. Clinical Relevance: Therapeutic strategies for microfracture augmentation, such as those presented in this study, can be cost-effective ways to improve cartilage healing outcomes, especially in more active patients.
Image-Guided Intra-articular Hip Injections and Risk of Infection After Hip Arthroscopy
Authors: Varady Nathan H. , Amen Troy B. , Abraham Paul F. , Chopra Ahab , Freccero David M. , Smith Eric L. , Martin Scott D. 
Published: June 2021

Background: Although intra-articular injections are important in the management of patients who may later undergo hip arthroscopy, conflicting data are available regarding the safety of such injections when administered within 3 months of surgery. Furthermore, despite the increasing use of image-guided intra-articular hip injections, it is unknown whether the type of imaging modality used is associated with infection after hip arthroscopy. Purpose: To assess the risk of infection associated with image-guided intra-articular injections before hip arthroscopy and, secondarily, compare that risk between ultrasound (US) and fluoroscopic (FL) guidance. Study Design: Cohort study; Level of evidence, 3. Methods: This was a retrospective cohort study of patients in a large national insurance database who underwent hip arthroscopy between 2007 and 2017. Patients were required to have continuous enrollment from at least 1 year before to 6 months after hip arthroscopy. Patient age, sex, geographic region, medical history, surgical details, and hip injections were collected. Patients who underwent injection ≤3 months preoperatively and >3 to ≤12 months preoperatively were compared with patients who did not undergo preoperative injection. Bivariate analyses and multivariable logistic regressions were used to assess the association between ipsilateral preoperative hip injection and surgical site infection within 6 months of surgery. Results: We identified 17,987 patients (36.3% female; mean ± SD age, 37.6 ± 14.0 years) undergoing hip arthroscopy, 2276 (12.7%) of whom had an image-guided hip injection in the year preceding surgery (53.0% FL). Patients who underwent intra-articular injection ≤3 months preoperatively had similar infection rates to patients who did not undergo preoperative injection in the year before surgery for both the FL (0.46% vs 0.46%; P≥ .995) and the US cohorts (0.50% vs 0.46%; P = .76). Results persisted in adjusted analysis (FL ≤3 months: OR, 1.04; 95% CI, 0.32-3.37; P = .94; US ≤3 months: OR, 1.19; 95% CI, 0.36-3.90; P = .78). Similar results were seen for patients undergoing injections >3 to ≤12 months preoperatively. Conclusion: Postoperative infection was rare in patients undergoing intra-articular hip injection ≤3 months before hip arthroscopy and was no more common than in patients not undergoing preoperative injection. Moreover, no differences were seen in infection risk between US and FL guidance. Although intra-articular hip injections should always be administered with careful consideration, these results do not suggest that these injections are uniformly contraindicated in the 3 months preceding hip arthroscopy.
Traduction française, adaptation culturelle et évaluation des propriétés psychométriques préliminaires de l’échelle des stratégies de protection comportementale liées à la consommation de cannabis
Authors: Côté José , Auger Patricia , Pagé Gabrielle M. , Cossette Sylvie , Coronado-Montoya Stephanie , Fontaine Guillaume , Chicoine Gabrielle , Rouleau Geneviève , Genest Christine , Lapierre Judith , Jutras-Aswad Didier 
Published: June 2021

Objectif: Les jeunes de 18 à 24 ans constituent la plus grande proportion de consommateurs de cannabis. Dans un contexte de légalisation de cette substance, il importe de promouvoir une consommation à moindre risque. L’échelle Protective Behavioral Strategies for Marijuana Scale (PBSM-17) permet d’identifier les stratégies de protection comportementale utilisées chez les consommateurs. Toutefois, cette échelle n’est pas disponible en français et n’est pas adaptée au contexte canadien. Cet article présente la démarche ayant mené à la traduction, l’adaptation culturelle et l’évaluation des propriétés psychométriques préliminaires du PBSM-17. Méthode: L’étude méthodologique s’est déroulée en six étapes. Les quatre premières étapes ont mené à la traduction et l’adaptation de l’échelle. La validation auprès de 12 jeunes a permis d’établir l’équivalence conceptuelle. L’évaluation des propriétés psychométriques a été réalisée auprès de 211 étudiants universitaires bilingues (61 % femme; âge moyen 22 ans). Résultats: La version traduite et adaptée présente des propriétés psychométriques préliminaires satisfaisantes : la cohérence interne est acceptable (α = 0,88); l’équivalence de critères (validité de construit) est établie entre la version française et la version anglaise ( t (210) = 1,04, p = 0,30 ; IC 95 % [-0,20, 0,63]). Les scores obtenus aux deux versions par le même participant s’avèrent fortement corrélées (r = 0,95, p < 0,001). Conclusion: Les résultats soutiennent l’utilisation de la version française du PBSM-17. Les stratégies de protection proposées peuvent être utilisées comme outil de mesure et représentent des comportements à adopter dans un contexte d’usage du cannabis à moindre risque.