bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Influencing Press Ganey Ambulatory Surgery Scores in Patients Undergoing Upper Extremity Procedures
Authors: Weir Tristan B. , Zhang Tina , Jauregui Julio J. , Aneizi Ali , Sajak Patrick M.J. , Schneider Matheus B. , Gilotra Mohit N. , Abzug Joshua M. , Henn R. Frank , Akabudike Ngozi M. 
Published: June 2021

Introduction:
We sought to determine whether patient and surgical factors are associated with the Press Ganey Ambulatory Surgery Survey (PGAS) satisfaction scores in patients undergoing outpatient upper extremity procedures.

Methods:
A retrospective review of a single academic urban hospital's Press Ganey database was performed for patients undergoing upper extremity procedures. PGAS scores above an a priori threshold were considered satisfied. Logistic regression analyses for the PGAS Total and Provider Scores were performed to determine the predictors of patient satisfaction.

Results:
Of the 198 patients included, the mean age was 49.6 ± 17.1 years and 55% were men. For the Total Score, multivariable analysis showed significantly less satisfaction with continuous catheter peripheral brachial plexus nerve blocks (CC-PNBs) (odds ratio [OR], 0.37; P = 0.008) and internet surveys (OR, 0.39; P = 0.007), but smokers had surprisingly more satisfaction (OR, 4.90; P = 0.016). For the Provider Score, a multivariable analysis showed less satisfaction with CC-PNBs (OR, 0.45; P = 0.035), internet surveys (OR, 0.46; P = 0.026), and geographic location (OR, 0.40; P = 0.005). Preoperative Patient-Reported Outcomes Measurement Information System scores were not associated with the PGAS scores.

Discussion:
Factors influencing satisfaction in patients undergoing upper extremity procedures may be modifiable (CC-PNBs and survey administration method) or nonmodifiable (geographic location) and may influence future reimbursement.
A Descriptive Study on Risk Factors for Common Non-Communicable Diseases among the Students of a Nursing Training School Attached To a Tertiary Care Hospital of West Bengal
Authors: Das Kamalika , Das Palash 
Published: June 2021

Introduction: Several risk factors would be the predominant cause of non-communicable diseases among the young adolescents girls life style modification maybe the methodology for health promotion & prevention of such non-communicable disease prevalence.
Objectives: To identify the several predisposing factors responsible for non-communicable health problems among the young adolescence.
Materials & Methods: Sample size was 212 and sampling technique was complete enumeration. A descriptive study was conducted where data analyzed through statistical methods like, chi square test.
Result: Study shows majority of the adolescent less than 20yers old and mostly from rural origin and non vegetarian. Most of them had the habit of vegetable & fruit intake though there was no case of addiction but only 56% were habituated with exercise.
Conclusion: Unhealthy diet pattern, lack of regular exercise would be the predominant cause of different non-communicable disease pattern where LSM is the best way to rectify the situation.
Effectiveness of Telemedicine Interventions In Diabetes Management At Primary Care Settings In Asia: A Systematic Review Protocol
Authors: Das Amity , Kaushal Pawna , Agarwal Disha , Sharma Megha 
Published: June 2021

Background: This systematic review will focus on the effectiveness of Telemedicine interventions on diabetic management at primary care settings in Asia. The objectives of this systematic review and meta-analysis are to synthesize the clinical effectiveness and to compare the effectiveness of Telemedicine interventions in the diabetes management in Asia.
Methodology: The conducting and reporting of this review will adhere to the PRISMA guidelines. The search strategy will include MeSH terms related to Diabetes, Telemedicine, Diabetic management, Primary Healthcare, Effectiveness, and Asia to find relevant studies. Other synonymous words will be searched using Boolean operator “AND”/”OR” on PUBMED, EMBASE, SCOPUS, COCHRANE. Randomized controlled trials examining the effectiveness of telemedicine interventions in the management of Diabetes Mellitus patients at Primary Care settings in Asia will be included. A random effects meta-analysis will be conducted with the REVMAN software version 5.3.5. Cumulative and comparative meta-analysis will be done with STATA software version SE16.
Discussion: This review and meta-analysis will be among the first to give an extensive purview on the effectiveness of telemedicine in diabetes management at Primary Care settings in Asian population.
Systematic review registration: The protocol has been registered at the International Prospective Register of Systematic Reviews (PROSPERO registration number: 42021210002).
Planning for resilience of water networks under earthquake hazard
Authors: Uma S R , Scheele Finn , Abbott Elizabeth , Moratalla Jose 
Published: June 2021

Water networks are vulnerable to earthquakes and failures of network components can result in a lack of availability of services, sometimes leading to relocation of the community. In New Zealand, there are statutory requirements for the water network providers to address the resilience of infrastructure assets. This is done by identifying and managing risks related to natural hazards and planning for appropriate financial provision to manage those risks. In addition to this, the impact from the Canterbury region earthquakes has accelerated the need for understanding the potential risk to critical infrastructure networks to minimise socio-economic impact. As such, there is a need for developing pragmatic approaches to deliver appropriate hazard and risk information to the stakeholders.
Within the context of improving resilience for water networks, this study presents a transparent and staged approach to risk assessment by adopting three significant steps: (i) to define an earthquake hazard scenario for which the impact needs to be assessed and managed; (ii) to identify vulnerable parts of the network components; and (iii) to estimate likely outage time of services in the areas of interest. The above process is illustrated through a case study with water supply and wastewater networks of Rotorua Lakes Council by estimating ground motion intensities, damage identification and outage modelling affected by number of crews and preferred repair strategies.
This case study sets an example by which other councils and/or water network managers could undertake risk assessment studies underpinned by science models and develop resilience management plans.
Characterisation of transport resilience and measures to enhance resilience in the recovery after the 2016 Kaikōura earthquake
Authors: Mason Dougal , Brabhaharan Pathmanathan 
Published: June 2021

The Ward to Cheviot section of State Highway 1 is a key lifeline transport route that runs through the Kaikōura township. It is a strategically important link in the national state highway network, connecting the North Island via the Wellington-Picton ferry to the city of Christchurch in the South Island. Its strategic importance and vulnerable location between the mountainous Kaikōura range and the Pacific Ocean make it a critical transportation route in the national transport network. The route has been a focus for understanding the resilience of transport networks from as far back as 2000, when this section was used as a pilot study in early research into transport resilience. A further resilience assessment of this section was completed as part of a national state highway resilience study in mid-2016. Subsequently, the Mw 7.8 Kaikōura earthquake struck the northeast of the South Island on 14 November 2016, triggering thousands of large landslides and causing severe disruption to the transport network. The damage and disruption caused by the earthquake was comparable to that assessed in pre-earthquake studies of the resilience of the state highway. Landslides and embankment failures caused the most damage and disruption to the transport infrastructure, with the Main North Line railway closed for over 9 months and State Highway 1 closed for over a year. Post-earthquake landslides and debris flows triggered by storms caused additional damage and disruption during the recovery phase. Post-earthquake assessment of the corridor resilience was carried out to identify measures to enhance resilience as part of the recovery works. These measures included realigning the road and rail away from the steep hillsides, engineered works to reduce the potential for slope failure, and engineered works to reduce the potential for inundation of the corridor. The resilience assessments also enabled tactical and operational measures to be put in place to ensure safety while allowing the recovery operations to proceed in the context of enhanced risk associated with storm events and potential aftershocks.
Strengthening heritage tunnels to enhance the resilience of Wellington’s transport network
Authors: Gkeli Eleni , Brabhaharan Pathmanathan , Novakov Dejan , Arumugam Siva , Mookaiya Gunasekaran 
Published: June 2021

Wellington city is characterised by steep hilly terrain, and as such several tunnels have been constructed since the beginning of the last century to provide critical transport access in the city. These tunnels are still used today as part of the city’s transport routes, while also being an integral part of the city’s history and heritage.
Wellington is among the most seismically active areas in New Zealand. Three major active faults located within the Wellington Region and the proximity to the subduction zone are the main contributors to the high seismicity. The aging tunnels were designed and constructed prior to the advent of earthquake design standards and are subject to deterioration. Hence, they require maintenance and strengthening to ensure operational integrity and resilience to earthquake and other hazard events. Authorities have been supported by the authors in managing the risk through identifying key vulnerabilities, and prioritisation and implementation of strengthening measures. Best practice investigation and strengthening techniques have been applied through the process to ensure resilience and cost effectiveness.
The paper presents case histories that highlight the value of investigations and assessment in understanding the risks, and novel strengthening measures developed to enhance resilience while preserving the heritage of the tunnels. Case histories include the seismic strengthening of the Hataitai Bus Tunnel, the Northland and Seatoun road tunnels and the investigation and assessment of the iconic Wellington Cable Car tunnels.
ON A CLASS OF MEROMORPHIC STARLIKE FUNCTIONS WITH NEGATIVE COEFFICIENTS
Authors: DIXIT K. K. , PAL S. K. 
Published: June 2021

Let $T^*_M(A, B, z_0)$ denote the class of functions
\[f(z)=\frac{a}{z}-\sum_{n=1}^\infty a_nz^n, a\ge 1, a_n\ge 0\]

regular and univalent in unit disc $U'=\{z:0<|z|<1\}$,

satisfying the condition
\[-z\frac{f'(z)}{f(z)}=\frac{1+Aw(z)}{1+Bw(z)}, \quad \text{ for } z\in U' \text{ and } w\in E\]

(where $E$ is the class of analytic functions $w$ with $w(0) = 0$ and $|w(z)| \le 1$), where $-1\le A < B \le 1$, $0\le B \le 1$ and $f(z_0) =1/z_0$ ($0<z_0<1$). In this paper sharp coefficient estimates, distortion properties and radius of meromorphic convexity for functions in $T^*_M(A, B, z_0)$ have been obtained. We also study integral transforms of functions in $T^*_M(A, B, z_0)$. In the last, it is proved that the class $T^*_M(A, B, z_0)$ is closed under convex linear combinations.
Seafloor Pipeline Detection With Deep Learning
Authors: Schøyen Vemund Sigmundson , Warakagoda Narada Dilp , Midtgaard Øivind 
Published: June 2021

This paper presents fast, accurate, and automatic methods for detecting seafloor pipelines in multibeam echo sounder data with deep learning. The proposed methods take inspiration from the highly successful ResNet and YOLO deep learning models and tailor them to the idiosyncrasies of the seafloor pipeline detection task.
We use the area between lines and Hausdorff line distance functions to accurately evaluate how well methods can localize (pipe)lines. The same functions also show promise as loss functions compared to standard mean squared error, which does not include the regression variables' geometrical interpretation.
The model outperforms the highest likelihood baseline by more than 35% on a region-wise F1-score classification evaluation while being more than eight times more accurate than the baseline in locating pipelines. It is efficient, operating at over eighteen 32-ping image segments per second, which is far beyond real-time requirements.
Effect of gestational age on levels of serum alkaline phosphatase isoenzymes in healthy pregnant women
Authors: Okesina A.B. , Donaldson D. , Lascelles P.T. , Morris P. 
Published: July 2002

AbstractObjectives: To confirm that the bone isoenzyme of alkaline phosphatase (ALP) contributes significantly to the increased ALP in normal pregnancy, and to determine the gestational age at which the increase occurs. Methods: Cross‐sectional determinations of serum total, bone and placental ALP were carried out in 67 normal pregnant women. The results were compared with those of 18 normal age‐matched non‐pregnant controls using Student's t‐test. Results: At both 31–32 weeks and 38 weeks of gestation, serum activities of bone ALP were increased significantly (P < 0.05 and P < 0.001, respectively) when compared with controls. The percentage contribution of bone ALP to the total was higher at 31–32 weeks and lower at 38 weeks when compared with the contribution from placental ALP. Conclusion: Knowledge of time of elevation of serum bone ALP activity in normal pregnancy will be helpful in the interpretation of elevated serum total ALP activity during pregnancy.
A 26–30 kDa developmentally‐regulated tauisoform localized within nuclei of mitotic humanneuroblastoma cells
Authors: Shea Thomas B. , Cressman Corine M. 
Published: July 2002

AbstractTau isoforms migrating at 46–68 and 97–115 kDa were prominent within heat‐stableTriton‐soluble material, and were present in lesser concentration within Triton‐insolublecytoskeletons, derived from undifferentiated SH‐SY‐5Y human neuroblastoma cells. Conversely,a 26–30 kDa tau isoform was enriched in the cytoskeleton and detected at relatively minor levelswithin cytosolic fractions. Pulse labeling with 35S‐methionine indicated that this 26–30kDa small tau did not represent a breakdown product of larger isoforms. Since the nucleus isretained within the Triton‐insoluble cytoskeleton, additional cultures were fractionated ontosucrose to obtain purified nuclei. The vast majority of small tau was recovered within purifiednuclei. Small tau was reactive with tau antibodies directed towards N‐terminal, C‐terminal andcentral epitopes, further confirming that this small isoform was not derived from proteolyticcleavage of larger tau isoforms. Small tau demonstrated alkaline phosphatase‐sensitive reactivitywith multiple phospho‐dependent tau antibodies. Small tau was depleted within 3 days of retinoicacid‐induced differentiation, suggesting that the putative function of this isoform may be obsoletefollowing terminal differentiation of neurons.
Fava's Anger Attacks Questionnaire: evaluation of the French version in depressed patients
Authors: Morand P , Thomas G , Bungener C , Ferreri M , Jouvent R 
Published: July 2002

SummaryThe prevalence, symptomatology and correlates of anger attacks were studied in 103 depressed French patients, using a French version of the Anger Attacks Questionnaire. The prevalence of anger attacks during the previous month was 46.7%, and the most frequently reported symptoms were feeling of panic (85.1%), tachycardia (83.7%), and feeling out of control (81.3%). The occurrence of anger attacks was significantly associated with intensity of loss of control, and history of panic attacks. There was no significant association with age, gender, severity of depression or anxiety, history of suicidal attempts or mood disorder. Three weeks of treatment with serotoninergic antidepressants induced a significant decrease in anger attack prevalence.
Application of industrial scale genomics to discovery of therapeutic targets in heart failure
Authors: Mehraban Fuad , Tomlinson James E. 
Published: July 2002

AbstractIn recent years intense activity in both academic and industrial sectors has provided a wealth of information on the human genome with an associated impressive increase in the number of novel gene sequences deposited in sequence data repositories and patent applications. This genomic industrial revolution has transformed the way in which drug target discovery is now approached. In this article we discuss how various differential gene expression (DGE) technologies are being utilized for cardiovascular disease (CVD) drug target discovery. Other approaches such as sequencing cDNA from cardiovascular derived tissues and cells coupled with bioinformatic sequence analysis are used with the aim of identifying novel gene sequences that may be exploited towards target discovery. Additional leverage from gene sequence information is obtained through identification of polymorphisms that may confer disease susceptibility and/or affect drug responsiveness. Pharmacogenomic studies are described wherein gene expression‐based techniques are used to evaluate drug response and/or efficacy. Industrial‐scale genomics supports and addresses not only novel target gene discovery but also the burgeoning issues in pharmaceutical and clinical cardiovascular medicine relative to polymorphic gene responses.
Familial dilated cardiomyopathy: clinical features in French families
Authors: Mangin Laurence , Charron Philippe , Tesson Frédérique , Mallet Alain , Dubourg Olivier , Desnos Michel , Benaïsche Azziz , Gayet Christian , Gibelin Pierre , Davy Jean‐Marc , Bonnet Jacques , Sidi Daniel , Schwartz Ketty , Komajda Michel 
Published: July 2002

AbstractThe aims of the study were to analyze the clinical features, the penetrance and the mode of inheritance of 13 French families with dilated cardiomyopathy using diagnostic criteria recently established by a European collaboration.Methods:Screening consisted of physical examination, ECG and Echo of all the probands first degree relatives (n=118). Using major Echo criteria [ejection fraction (EF) < 45% or FS< 25% and left ventricular diameter (LVD) > 117% of the predictive value], or combined minor Echo/ECG criteria, relatives were classified as affected, unknown or healthy.Results:(1) Adult affected relatives (n=31) were identified with major Echo criteria in 74% of cases, and with combined minor Echo/ECG criteria in 26% of cases. (2) In the unknown relatives (n=21), the most common abnormality was an isolated left ventricular dilation (67%). (3) Mode of inheritance was autosomal dominant (AD) in 11 families and possibly autosomal recessive in two. (4) In AD families, the penetrance was incomplete in adults (72%), age‐related (O.R.: 1.3 per 10 years; 95% CI 1.03–1.56) and sex‐related [greater in men (87%) than in women (61%), actuarial survival curve: P < 0.002]. (5) Mortality related to end stage heart failure was 2.2 times as high as mortality related to sudden death (11% vs. 5%).Conclusions:(1) In the absence of a specific phenotype of FDC, the characterization of relatives appears more accurate when minor criteria were added. (2) Since high mortality (16%) and incomplete penetrance frequently give rise to small nuclei of clinically affected and alive relatives per family, the accurate model of penetrance that we proposed might be helpful in the future to enhance the statistical power of linkage analysis in this disease.
Crystal structures of a nicotine MATE transporter provide insight into its mechanism of substrate transport
Authors: Tanaka Yoshiki , Iwaki Shigehiro , Sasaki Akira , Tsukazaki Tomoya 
Published: June 2021

A transporter of the multidrug and toxic compound extrusion (MATE) family, Nicotiana tabacum MATE2 (NtMATE2), is located in the vacuole membrane of the tobacco plant root and is involved in the transportation of nicotine, a secondary or specialized metabolic compound in Solanaceae. Here, we report the crystal structures of NtMATE2 in its outward‐facing forms. The overall structure has a bilobate V‐shape with pseudo‐symmetrical assembly of the N‐ and C‐lobes. In one crystal structure, the C‐lobe cavity of NtMATE2 interacts with an unidentified molecule that may partially mimic a substrate. In addition, NtMATE2‐specific conformational transitions imply that an unprecedented movement of the transmembrane α‐helix 7 is related to the release of the substrate into the vacuolar lumen.
Three‐Dimensional Printed Mechanically Compliant Supercapacitor with Exceptional Areal Capacitance from a Self‐Healable Ink
Authors: Kang Wenbin , Zeng Li , Ling Shangwen , Lv Chunzheng , Liu Jingfeng , Yuan Ruoxin , Zhang Chuhong 
Published: June 2021

AbstractKnown for its capability to architect tailored structures for the scaling of active materials in energy storage devices that cater for future electronics having stringent requirements on areal performance, 3D printing is receiving serious attention. However, lingering challenges originating from the notorious interfacial issue and weak component interaction restrain current devices from making a breakthrough in deliverable capacity and structural flexibility. In this work, the printed electrode delivers a record‐breaking electrical double layer (EDL) areal capacitance of 27.1 F cm−2 under an extremely large loading density of 134 mg cm−2. This translates to a deliverable record‐high EDL energy density of 1.26 mWh cm−2 for device performance, which even rivals the highest value reported from highly loaded pseudocapacitors. The bespoke devices are enabled by a strategically formulated 3D printable ink that initiates efficient autonomous room‐temperature self‐healing and strong interplay between constituting ink components. These contribute to interlayer coalescing for eliminated interlayer resistance for a solid electrochemical performance and printed electrodes of great mechanical compliance. By tapping into the huge potential of 3D printing, this work lays a solid foundation on which flexible devices with customized geometry, functionality, and outstanding performance for a broad range of applications can be readily realized.
Development of the inorganic nanoparticles reinforced alginate‐based hybrid fiber for wound care and healing
Authors: Weng Lin , Zhang Xiaolin , Fan Wei , Lu Yao 
Published: June 2021

AbstractIt is necessary for wound dressing constructed from fibers capable of overcoming external stretching and protecting injured skin. The limited mechanical performance of existing alginate fiber limits its biomaterial application. Herein, this issue can be addressed via incorporation of uniformly dispersed hydroxyapatite (HAP) and silica (SiO2) nanoparticles (NPs) in alginate (Alg) by microfluidic spinning technique. These NPs serve as a reinforcing phase to help the alginate‐based composite to develop outstanding mechanics. Both HAP‐Alg and SiO2‐Alg hybrid fibers exhibited excellent breaking elongation, 67.56 ± 6.85% and 52.08 ± 5.20% respectively, while that of breaking strength were 7.04 ± 0.58 MPa and 4.96 ± 0.59 MPa. Furthermore, in vitro cytotoxicity was explored by studying on the proliferation and migration of keratinocytes and fibroblasts, which illustrated no obvious cytotoxicity of the resulting alginate fibers loaded with HAP and SiO2 NPs. The artificial scratch assay demonstrated that the resulting alginate‐based composite fiber can assist the injured skin regeneration. This work provides a significant progress in the conception of developing NPs reinforced alginate‐based hybrid fiber which can withstand the large strain behavior and facilitate wound healing, making it an ideal candidate as wound dressings and fibrous scaffolds.