bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH PEMBERIAN EKSTRAK ETANOL HERBA BANDOTAN (Ageratum conyzoides) TERHADAP PENURUNAN KADAR KOLESTEROL TOTAL DAN TRIGLISERIDA PADA MENCIT (Mus musculus) HIPERLIPIDEMIA
Authors: Puspita Indah , Fakhruddin Fakhruddin , Irawan Yogie 
Published: November 2021

Pendahuluan: Hiperlipidemia merupakan suatu keadaan patologis yang disebabkan oleh kelainan dari metabolisme lipid darah yang umumnya ditandai dengan meningkatnya kadar trigliserida, kolesterol total, Low Density Lipoprotein (LDL) serta penurunan kadar High Density Lipoprotein (HDL)Metode: Penelitian ini menggunakan mencit putih jantan sebanyak 20 ekor yang terlebih dahulu diinduksi propiltiurasil dan diet pakan tinggi lemak. Pengujian terdiri dari 5 kelompok, yaitu kelompok kontrol positif (simvastatin 1,3 gr/kgBB), kelompok kontrol negatif (Na CMC 0.5%) dan kelompok perlakuan dengan pemberian ekstrak etanol herba bandotan dengan dosis 0,5 gr/kgBB; 1,5 gr/kgBB dan 2 gr/kgBB melalui oral selama 14 hari.Hasil: Hasil uji statistika ANOVA menyatakan terdapat pengaruh Herba Bandotan dalam menurunkan kadar kolesterol total dan trigliserida yang sebanding dengan kontrol positif dengan hasil (p< 0,05). Kemudian pada uji LSD menyatakan kelompok perlakuan dengan dosis 2 gr/kgBB memiliki kemampuan paling baik diantara kelompok perlakuan dosis ekstrak lainnyaKesimpulan: Terdapat pengaruh pemberian ekstrak etanol herba bandotan (Ageratum conyzoides) terhadap penurunan kadar kolesterol total dan trigliserida pada mencit hiperlipidemia Kata Kunci:Herba bandotan (Ageratum conyzoides), hiperlipidemia, kolesterol total, trigliserida,
PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN KARAMUNTING (Rhodomyrtus tomentosa (Ait.) Hassk.) TERHADAP KADAR KOLESTEROL DAN TRIGLISERIDA PADA MENCIT PUTIH HIPERLIPIDEMIA
Authors: Anggraeni Lucky Novia , Fakhruddin Fakhruddin , Irawan Yogie 
Published: November 2021

Pendahuluan: Hiperlipidemia merupakan salah satu faktor risiko dari penyakit kardiovaskular yang disebabkan oleh terbentuknya aterosklerosis pada pembuluh darah. Hiperlipidemia dapat terjadi karena faktor genetik serta gaya hidup yang tidak sehat. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol daun karamunting (Rhodomyrtus tomentosa (Ait.) Hassk.) terhadap kadar kolesterol total dan trigliserida pada mencit putih hiperlipidemia.Metode: Pada penelitian ini menggunakan 20 ekor mencit putih jantan yang terbagi menjadi 5 kelompok mencit hiperlipidemia yaitu kelompok kontrol positif (Simvastatin 0,026 mg/20grBB), kelompok kontrol negatif (Na CMC 0,5%) sedangkan kelompok perlakuan ekstrak etanol daun karamunting dosis 14 mg/20grBB, 28 mg/20grBB dan 56 mg/20grBB. Pengukuran kadar kolesterol total dan trigliserida dilakukan pada hari ke-0, hari ke-14 dan hari ke-28. Presentase penurunan kadar kolesterol total dan trigliserida darah mencit dianalisis menggunakan Uji One Way Anova dan Post Hoc LSD.Hasil: Berdasarkan hasil uji statistika menyatakan bahwa tidak ada perbedaan signifikan pada penurunan kadar kolesterol total kelompok kontrol positif dengan kelompok perlakuan dosis 56 mg/20grBB dengan nilai signifikan (p > 0,05) dan tidak ada perbedaan signifikan pada penurunan kadar trigliserida kelompok kontrol positif dengan kelompok perlakuan dosis 14 mg/20grBB, 28 mg/20grBB dan 56 mg/20grBB dengan nilai signifikan (p > 0,05).Kesimpulan: Ekstrak etanol daun karamunting dosis 56 mg/20grBB dapat memberikan penurunan kadar kolesterol total dan trigliserida pada mencit hiperlipidemia.Kata Kunci : daun karamunting, kolesterol total, trigliserida, hiperlipidemia
FAMÍLIA, ESCOLA E TRANSIÇÃO ECOLÓGICA: UMA REVISÃO INTEGRATIVA DA LITERATURA NACIONAL
Authors: Guisso Luciane , Motta Cibele 
Published: November 2021

Este trabalho visa apresentar uma revisão integrativa da literatura nacional referente a família, escola e transição para a escolaridade. Assim, realizou-se uma busca de artigos científicos nas bases de dados SciELO e Pepsic, para mapear a produção nacional sobre o tema nos últimos dez anos (2006-2016). Mediante a combinação de palavras-chaves, encontraram-se 17 artigos que discutem a relação entre família e escola e como ocorre a transição da criança pequena para o contexto escolar. A análise dos artigos evidenciou que a entrada da criança na escola tende a ser vivenciada tanto pela família quanto pela criança como período de estresse, pois envolve a adaptação de todos. O clima familiar positivo permeado por práticas educativas do tipo indutivas e a participação ativa na vida escolar das crianças possibilitam que as famílias experimentem esse momento de transição para a escolarização de forma mais satisfatória.
Prevalence and Associations of General Practice Registrars’ Management of Atopic Dermatitis: A Cross-Sectional Analysis from the Registrar Clinical Encounters in Training Study
Authors: Willems Anneliese , Tapley Amanda , Fielding Alison , Tng Er Tsing Vivian , Holliday Elizabeth , Van Driel Mieke L , Ball Jean , Davey Andrew , Patsan Irena , FitzGerald Kristen , Spike Neil , Magin Parker 
Published: November 2021

Introduction: Atopic dermatitis (AD) is a chronic inflammatory condition which imposes substantial burden upon patients and their families. As a frequent primary care presentation, general practice (GP) trainees must develop adequate skills in AD diagnosis and management.
Objectives: We aimed to explore the prevalence and associations of GP registrars’ management of patients with AD.
Methods: This study used data from the Registrar Clinical Encounters in Training (ReCEnT) project, an ongoing cohort study of the clinical and educational experience of Australian GP registrars. Registrar, patient, and consultation factors were independent variables in multivariable logistic regression with outcome factor ‘diagnosis/problem being AD’.
Results: From 2010-2019, 2,783 registrars (96% response rate) provided data from 381,180 consultations. AD was encountered in 0.6% of consults. AD was more likely to be seen in patients aged 0-1 years and patients from a non-English speaking background. AD was less likely to be seen in Aboriginal or Torres Strait Islander patients. Learning goals were more likely to be generated for AD and these consultations were associated with registrars seeking information or assistance. AD was strongly associated with a medication being prescribed, of which the most prescribed medications were mild or moderate potency topical corticosteroids.
Conclusions: Our findings suggest that, similar to other dermatological presentations, registrars find AD challenging to manage. There may be some gaps in AD management knowledge and application.
Patients with Hidradenitis Suppurativa Negatively Perceive Both Medical and Euphemistic Appellations of Their Disease: A Study From Turkey
Authors: Akoglu Gulsen , Esme Pelin , Yildiz Irem 
Published: November 2021

Background: The use of medical terms and folk names (euphemisms) affect a patient’s understanding of diseases and perceptions of severity.
Objectives: We determine the psychological effects on patients with hidradenitis suppurativa of medical and folk names of their disease.
Methods: This was a cross-sectional and exploratory study conducted at a tertiary referral university hospital in Turkey. A questionnaire on the medical and folk names of hidradenitis suppurativa was administered to 31 males and 25 females.
Results: The patients expressed that they found the medical term hidradenitis suppurativa to be incomprehensible because it is a foreign term. When hearing it for the first time, it evoked negative responses such as confusion and worry about their health. Half of the patients preferred their doctors to use a more understandable and pronounceable name. More than 80% of patients expressed feeling depressed and stigmatized by the folk name of their disease. They preferred the terms boils, abscesses, or hidradenitis when referring to their disease.
Conclusion: Both medical and folk names for hidradenitis suppurativa have negative effects on patients, and most patients feel stigmatized by either term.
Efeito dos Antivirais de Ação Direta nos parâmetros bioquímicos da Síndrome Metabólica em pessoas com hepatite C
Authors: Rocha Mariana Balhego , Ziolkowski Mariana Ilha , Bittencourt Raqueli Altamiranda , Quintana Luciane Dias , Bender Eduardo André 
Published: November 2021

Na fase crônica da hepatite C pode ocorrer manifestações extra-hepáticas, como doenças cardiometabólicas, que estão entre as principais causas de morte por doenças crônicas não transmissíveis no mundo. Objetivo: Avaliar a prevalência de Síndrome Metabólica (SM) e as características de uma coorte de pacientes com hepatite C de Uruguaiana/RS e prever o efeito dos Antivirais de Ação Direta nos parâmetros bioquímicos da SM. Métodos: Trata-se de um estudo de Coorte Retrospectiva, em que as variáveis sociodemográficas, antropométricas, pressóricas e bioquímicas foram coletadas a partir de prontuários. Foi utilizado os critérios da International Diabetes Federation para a classificação da SM. A análise estatística envolveu os testes de Kolmogorov-Smirnov, teste t de Student e qui-quadrado de Pearson, regressão logística binária. Resultados: Foi possível verificar alta prevalência de SM na maioria dos pacientes e traçar um perfil dos indivíduos. O tratamento composto por Sofosbuvir e Daclatasvir não influenciou na glicemia e HDL-c, mas apresentou menores chances de hipertrigliceridemia após o tratamento. Considerações finais: Os resultados demonstram relevância e permitem criar metas eficazes de cuidado aos pacientes com hepatite C e comorbidades. O desenvolvimento de ações de prevenção, planejamento e estratégias econômicas influenciam positivamente no bem-estar dos pacientes e na alocação de recursos públicos, reduzindo os custos com essas doenças.
Impacto do cuidado farmacêutico nos desfechos clínicos de um paciente com diabetes tipo 2 em uso de insulina: relato de caso
Authors: BAYER MILLENA , BORBA HELENA HIEMISCH  LOBO 
Published: November 2021

Na equipe interdisciplinar, o farmacêutico atua no tratamento do diabetes utilizando seus conhecimentos sobre medicamentos para garantir que as necessidades do paciente sejam atendidas. Este estudo objetivou avaliar os desfechos clínicos de um paciente com diabetes tipo 2 (DM2) em uso de insulina, assistido pelo cuidado farmacêutico realizado por residentes em saúde da família, em unidade básica de saúde do município de Piraquara, PR. Trata-se de um relato de caso no qual os dados foram obtidos a parir de um estudo de coorte descritivo. Inicialmente, foram identificados os problemas relacionados à farmacoterapia e após seis meses de acompanhamento farmacoterapêutico obteve-se redução de 2,06% na hemoglobina glicada e de 206 mg/dL na glicemia de jejum. Este relato demonstrou que o cuidado farmacêutico teve impacto positivo sobre o controle metabólico do paciente. São necessários estudos envolvendo amostras maiores para melhor estabelecer o impacto dos serviços farmacêuticos no cuidado ao paciente com DM2.
Chemical Composition and Biological Activities of Eugenia caryophyllata Thunb Essential Oil
Authors: Abdellah Fatiha , Boubakeur Badra , Ayad Noura , Boukraa Laid , Hammoudi Si Mohamed , Abdelhak Boumedienne , Benaraba Rachida 
Published: November 2021

Aims: In this study the antibacterial and antioxidant activities of the essential oil of Eugenia caryophyllata were investigated.
Study design: The study contains determination of the chemical composition of the essential oil of E. caryophyllata and the in vitro evaluation of the antibacterial and antioxidant activity of this oil.
Place and Duration of Study: The study was carried out at the laboratory of research on local animal products of Ibn-Khaldoun University, Tiaret, Algeria during the period from December 2020 to March 2021.
Methodology: The essential oil composition was characterized by gas chromatography/mass spectrophotometrical analyses. The antibacterial activity of this oil was tested against four pathogenic bacteria: Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 33862, Bacillus cereus ATCC 11778 by using disc diffusion method and agar incorporation method to determine the Minimum Inhibitory Concentration (MIC) of the tested oil. The antioxidant activity was evaluated by using DPPH radical scavenging, hydrogen peroxide scavenging assays and ferric reducing antioxidant power (FRAP) assay.
Results: Our results have shown a greater antibacterial effect of E. caryophyllata essential oil against all the bacterial tested strains with inhibition zone diameters varied from 17.5 to 20.5 mm and minimal inhibition concentration (MIC) ranged between 0.8 μl / ml and 4.4 μl / ml, B. cereus and S. aureus are the most sensitive species with a MIC value of 0.8 μl / ml, however P. aeruginosa is the most resistant species with a MIC value of 4.4 μl / ml. The result of the antioxidant effect showed that the essential oil of E. caryophyllata is a powerful antioxidant that expresses a higher antioxidant activity than the standard antioxidants: gallic acid, vitamin C and BHT.
Conclusion: The obtained results suggest that the essential oil of E. caryophyllata has a strong antibacterial and antioxidant effect and it may be an alternative natural source medicine to prevent and treat many diseases caused by pathogenic bacteria and oxidative stress.
Consumers’ Sustainable Choice between Gas and Electric Scooter
Authors: Balanquit Daisy Lily M. , G. Asinas Reann , De Veyra Alyssa R. 
Published: November 2021

Aims: To investigate consumers’ sustainable choice behavior between gas and electric scooters, as predicted by consumers’ felt responsibility for sustainability anchored on norm activation theory.
Study Design: Quantitative research approach using cross-sectional online survey design.
Place and Duration of Study: The data came from faculty employees of a state university in the Philippines between August to September 2020.
Methodology: 109 responses from faculty employees were analyzed. Hypotheses were tested for regression using Jamovi.
Conclusion: This study added empirical evidence on the applicability of consumers’ felt responsibility for sustainability as a predictor of sustainable choice behavior and answered the call for more studies that would promote a better understanding of the concept of sustainable consumption. The findings provided important implications on how marketers and managers can promote pro-environmental products such as electric scooters and boost sustainable consumption among buyers in an identified community.
Assessment of Right Ventricular Function and Structure in Children with Idiopathic Dilated Cardiomyopathy
Authors: Ahmed El-Fiky Drahem Mansour , El-Nemr Shimaa Basyony , El-Rasoul Tolba Osama Abd Rab , El-Shahaby Waleed Ahmed 
Published: November 2021

Background: Dilated cardiomyopathy (DCM) refers to dilating the ventricles and dysfunction of their systolic functions (predominantly the left ventricle) with or without congestive heart failure. In children, it is the most common form of heart muscle disease. We aimed to evaluate the right ventricular functions and structure using speckling tracking echocardiography in children with dilated cardiomyopathy and correlate this parameter with other echocardiographic findings.
Methods: This observational Case-Control Study was carried out on 75 subjects. They were subdivided into two groups: Group 1: 50 patients with dilated cardiomyopathy Group 2: 25 healthy children matched for age and sex. Patients were evaluated by M-mode echocardiography, Transthoracic 2DE Examination (TTE), Tissue Doppler Examination (TDE) and Speckling Tracking Technique.
Results: Left ventricle (LV) and right ventricle (RV) systolic dysfunction was evidenced by a significant decrease of mitral and tricuspid annular systolic velocities and a significant decrease of LV and RV global systolic strain and a significant decrease of LV and RV Ejection fraction (EF). LV and RV diastolic dysfunction were evidenced by a significant decrease of mitral and tricuspid annular diastolic velocities (E’/A’) and a significant increase of LV and RV Myocardial Perfusion Imaging (MPI). LV and RV global strains were significantly reduced in comparison to controls, suggesting that the dilated cardiomyopathy is a diffuse disease.
Conclusion: In DCM patients, RV had significant systolic and diastolic dysfunction mainly elicited by the Tissue Doppler imaging (TDI) beside LV affection secondary to the interventricular interaction. TDI and 2D-STE add value to interpreting the findings and the dependency of RV systolic and diastolic functions on each other in DCM patients.
Evaluation of the Vitamins and Possible Nutrient Composition of Local and Improved Specie of Guava Flesh (Psidium guajava)
Authors: Oguazu C. E. , Adimora K. H. , Anajekwu B. A. , Dike C. C. , Ikimi C. G. 
Published: November 2021

Background and Objectives: Guava (Psidium guajava) belongs to the family Myrtaceae. It has been cultivated in Nigeria one of the most common fruits in Nigeria. It has become popular because of its availability almost throughout the year. The objective of this study is to evaluate the nutritional and vitamin contents of the flesh of the local and improved guava species.
Materials and Methods: Proximate components were determined using the AOAC method for the moisture, ash, crude lipid, nitrogen content (crude protein) and Carbohydrate. Vitamins A, B1, B2, B3, B6 and B12 were analyzed using standard methods.
Results: The result showed that moisture and carbohydrate content of the improved white guava flesh is low compared with the local white guava species (9.8825 and 14.4015%) and (56.378 and 62.802%), respectively. The ash, fat, fibre and protein content of the improved white guava flesh are high compared with the local guava species (11.25 and 5.15%), (5.55 and 1.335%), (6.6145 and 6.5865%) and (10.325 and 8.225%). Improved White guava flesh is relatively low in Vitamin A, vitamin B3, vitamin B6 and vitamin C compared to local white guava flesh, while the local white guava flesh is relatively poor in vitamin B1, vitamin B2 and vitamin E compared to improved white guava flesh.
Conclusion: The present findings suggest guava flesh as a considerable source of nutrients in the diet and may have health and economic benefits due to its vitamins, and nutritional composition.
Comparative Effect of Different Treaments in Field Pea (Pisum sativum L.)
Authors: Sree Tharuna , Dayal Abhinav , Rai Prashanth Kumar 
Published: November 2021

A field study was conducted to investigate the various treatments that effect on growth and yield of field pea in RBD (Randomized block design) at Sam Higginbottom University of Agriculture Technology and Science, Prayagraj, Uttar Pradesh during march to May in 2020. The trail consists of 13 treatments combinations. The field pea varieties were used were IPF429. The treatments included T0- control, T1,T2,T3,-Gibberellic acid, T4,T5,T6- Neem leaf extract, T7,T8,T9-ZnSo4, T10T11T12- Naphthalene acetic acid(NAA). All Ten parameters treated with Ga3 shows good results in Yield and shows maximum in field emergence, plant height, Days to 50% flowering, Number of pods, Seed yield per plot, Biological Yield and Harvest index. T0 (Un primed) shows lowest of all treatments. Hence, priming with Gibberellic acid could recommended for pre sowing treatment for field pea.
Preliminary Assessment of Water Quality in Some Hydrocarbon-imparted Ogoni Communities in River State, Nigeria
Authors: Ganabel Caroline Barituka , Wachukwu Confidence Kinikanwo , Abbey Samuel Douglas , Nwokah Easter Godwin 
Published: November 2021

Aim: This study aimed to assess the quality of drinking water in some hydrocarbon-impacted Ogoni communities.
Study Design: The study employ a cross-sectional and analytical design using stratified sampling method.
Place and Duration of Study: Department of Medical Laboratory Science of Rivers State University, Giolee Global Resource Limited and Environmental Consultancy Services between March 2020 and March 2021.
Methodology: Water samples were collected from (20 hydrocarbon- impacted communities) in the 4 Local Government Area (LGAs) of Ogoni land. These water samples were analyzed to determine the physicochemical, bacteriological, heavy metal and total petroleum hydrocarbon (TPH) parameters using standard methods and operational procedures. The data obtained were subjected to descriptive statistical analysis. The general linearized model (GIG) was used to generate analysis of variance (ANOVA) mean and standard error and arrange, statistically significant was set as p-value of .05 (95% confidence limit). Pearson correlation test was used to calculate the correlation between TPH, Heavy metal, and physicochemical parameters in hydrocarbon and non-hydrocarbon impacted communities. All statistical analyses were performed using GraphPad Prism (Version 8).
Results: The results obtained for physicochemical parameters were pH 4.3±0.8 mg/l, EC 0.03±0.05 mg/l, DO 5.5±1.6 mg/l, Temp 25.0±0.0 mg/l, Mv 0.32±0.27 mg/l, Nitrite 0.0058±013 mg/l, Nitrate 0.1530±158 mg/l. These results were all below the recommended standard for Nigeria standard of drinking water quality (NSDWQ) and World Health Organization (WHO). The bacteriological analyses were carried out using multiple tubes technique (Most Probable Number), total coliform count, (TC), total heterotrophic count (THBC) and total fungal count (TFC). The results obtained were 0.941±2.397 cfu/ml, 89.3±176.6 cfu/ml, 297.8±144.4 cfu/ml, and 0.32±0.84 cfu/ml respectively. The p-values for TFC (<0.0002) were statistically significant. Heavy metal profiling was: Cr 0.194±0.320 mg/l, Cd 0.469±0.569 mg/l, Cu 0.211±0.348 mg/l, Pb 0.0336±0.20 mg/l, Fe 0.705±1.244 mg/l, Zn 0.258±0.249 mg/l, respectively. Generally, the concentration of heavy metal increased more than the standard recommended by NSDWQ and WHO except for Zn 0.255±0.249 mg/l, and Cu 0.56±0.50 mg/l, that is slightly lower than the acceptable limit recommended by WHO and NSWWQ. The sequences of heavy metal concentration were in Cd > Cr> Pb>Fe> Cu.>Zn. The statistical significance values for Pb p=.003 and for Zn p=.009 were statistically significant. The concentration of TPH were (349.9 ppm/ml) higher than the recommended values for NSDWQ and WHO.
Conclusion: The findings in this research reviewed a worrisome level of TPH and Pb, and which could have devastating impact on bacterial biodiversity.