bluuebunny/crossref_metadata_2025_split huggingface dataset:
CHOLINERGIC AGONISTS AGAINST COVID-19 IN HUMANS. RESULTS FROM A RANDOMIZED OPEN LABEL PILOT TRIAL
Authors: Angulo Orlando , Restrepo Hector Fabio , León Higuera José Gabriel , Leon Garcia Mario , Mendive Fernando , Politi Matteo 
Published: September 2021

Background:

Since the SARS-CoV-2 pandemic emerged in December 2019, it has triggered 4.4 million deaths and strained health systems across the world. Yet more than a year and a half since the pandemic emerged, therapeutic drugs to treat COVID-19 disease are limited.

Objective

To investigate the therapeutic potential of a nicotinic Cholinergic Agonists Mixture (CAM), delivered daily as oral drops and as nasal spray, in alleviating ten common COVID-19 related symptoms in 80 symptomatic human adults with confirmed SARS-CoV-2.

Methods

This randomized open-label pilot trial recruited 80 symptomatic adults with confirmed SARS-CoV-2 infection after RT-PCR+ test less than five days. Participants were recruited from databases of several Colombian hospitals and were randomly assigned to the control group, which received the Standard of Care (SOC) treatment (outpatient treatment), or the intervention group, which received SOC combined with the Cholinergic Agent Mixture (CAM + SOC). Both groups received their treatment for a total of 14 days. The duration of symptoms was compared across the 14-day period.

Results:

This study found statistically significant reductions in symptom duration for 5 out of 10 symptoms, including dyspnea (reduction of 4.43 days [95% CI: 2.70 ; 6.15], p <0.0001), cough (reduction of 3.18 days [95% CI: 1.29 ; 5.06], p=0.0089), cephalea (reduction of 3.13 days [95% CI: 1.53 ; 4.72], p= 0.0019), muscle fatigue (reduction of 4.18 days [95% CI: 2.03 ; 6.32], p=0.0019) and general malaise (reduction of 5.98 days [95% CI: 4.20 ; 7.76], p <0.0001).The study found no significant reductions in the duration of the following symptoms: fever, ageusia, anosmia, chest tightness, and nasal congestion.

Conclusion:

In comparison to the control group, the intervention group witnessed statistically significant and clinically relevant reductions in the duration of 5 out of 10 common COVID-19 disease symptoms within two weeks.

This includes a reduction of approximately 4.4 days in the duration of dyspnea, a symptom that appears to be strongly correlated to severe COVID-19 disease and admission to Intensive Care Units.

Further studies are needed to confirm these preliminary findings and to evaluate whether this specific nicotinic cholinergic agonists mixture could have implications for public health.
Analisis Pengambilan Keputusan Strategi Bisnis dalam Meningkatkan Penjualan Pada Usaha Langgang
Authors: Redaputri Appin Purisky , Alfarizi Dion 
Published: September 2021

Abstract
Kemplang Tunu (panggang) is one of the typical snack products from South Sumatra that is very popular by the community. Langgang's business is a new roast camper business established in June 2020.This research on business actors is a first step strategy in business development do that it can last in the long term, this triggers researchers to find out what alternative strategies are in accordance with Langgang's efforts in increasing sales. This research uses descriptive qualitative with Soft Systems Methodology (SSM) and Analytical Hierarchy Process (AHP) method and Expert Choice application as a tool in processing data supporting system decision making. The results of this study showed that internal factors four sub-criteria and external factors four sub-criteria. The results of the decision-making model using Analytical Hierarchy Process (AHP) stated that the alternative business strategy in Langgang business is the development of a new type of taste with an assessment of (0.387), sales via e-commerce with an assessment of (0.290), opening oulet with an assessment of (0.192) and selection of suppliers with an assessment of (0.131).

Keywords: Kemplang Panggang, Decision Making, Business Strategy, Analytical Hierarchy Process (AHP), Expert Choice

Abstrak
Kempang Tunu (Panggang) ialah produk olahan istimewa dari Sumatera Selatan dan sangat digemari oleh masyarakat. Usaha Langgang ialah usaha kemplang panggang yang baru didirikan pada bulan Juni 2020. Penelitian pelaku usaha ini merupakan strategi langkah awal pada pengembangan usaha hingga mencapai bertahan sampai jangka panjang, hal ini memicu peneliti untuk mencari tahu alternatif strategi apa yang sesuai dengan usaha Langgang dalam meningkatkan penjualan. Penelitian ini menggunakan kualitatif dekriptif dengan Soft Systems Methodology (SSM) dan metode Analytical Hierarchy Process (AHP) serta aplikasi Expert Choice sebagai alat dalam mengolah data sistem penunjang pengambilan keputusan. Hasil Penelitian ini menunjukkan bahwa faktor internal terdapat empat sub-kriteria dan faktor eksternal terdapat empat sub-kriteria. Hasil model pengambilan keputusan dengan menggunakan Analytical Hierarchy Process (AHP) menyatakan bahwa alternatif strategi bisnis pada usaha Langgang yaitu pengembangan jenis rasa baru dengan penilaian sebesar (0,387), penjualan via e-commerce dengan penilaian sebesar (0,290), membuka oulet dengan penilaian sebesar (0,192) dan pemilihan supplier dengan penilaian sebesar (0,131).

Kata kunci: Kemplang Panggang, Pengambilan Keputusan, Strategi Bisnis, Analytical Hierarchy Process (AHP), Expert Choice
Pengambilan Keputusan dalam Menentukan Lokasi Usaha pada Jasa Treatment Eternal.Lab Menggunakan Analytical Hierarchy Process
Authors: Rinova Dora , Imanuel.T Febrianto 
Published: September 2021

Abstract
Treatment Eternal.Lab is a business engaged in the services of washing shoes, bags, hats and helmets. There are several things that must be improved by eternal.lab treatment in order to survive and compete in the future. Decision making in determining the right location will have an impact on the development of the business in the future, then, there needs to be a strategy in determining the location of the business. Taking into account the segments and costs in determining the location will be able to deny profits to thebusiness. Analytical hierarchy process becomes the preferred method to see the location of the business where itis prioritized based on the criteria that influence in determining the location of the business on the treatment services Eternal.Lab. The author uses the expert choice tool to find out the value of each criterion and sub-criteria against alternative locations that have previously been selected. Obtained 4 (four) criteria that become determinants in determining the location of the business, namely facilities, rental costs, market environment, and physical condition of the location. Based on the results of the tests conducted, obtained alternative locations that are prioritized is the Queen's labuhan with an assessment weight (0.406).
Keywords: Decision Making, Business Location Selection, Business Location Strategy, Analytical Hierarchy Process

Abstrak
Treatment Eternal.Lab merupakan bisnis bergerak di bidang jasa pencucian sepatu, tas, topi dan helm. Terdapat beberapa hal yang harus dibenahi oleh treatment Eternal.Lab agar dapat bertahan dan bersaing kedepannya. Pengambilan keputusan dalam menentukan lokasi yang tepat akan berdampak pada perkembangan usaha tersebut kedepannya maka, perlu adanya strategi dalam menentukan lokasi usaha. Dengan mempertimbangkan segmen dan biaya dalam menentukan lokasi akan dapat meningkarkan keuntungan pada usaha. Analytical hierarchy process menjadi metode yang dipilih untuk melihat lokasi usaha dimana yang lebih di prioritaskan berdasarkan kriteria yang berpengaruh dalam menentukan lokasi usaha pada jasa treatment Eternal.Lab. Penulis menggunakan alat expert choice untuk mengetahui nilai setiap kriteria dan sub-kriteria terhadap alternatif lokasi yang sebelumnya sudah dipilih. Diperoleh 4 (empat) kriteria yang menjadi penentu dalam menentukan lokasi usaha yaitu fasilitas, biaya sewa, lingkungan pasar, dan kondisi fisik lokasi. Berdasarkan hasil dari pengujian yang dilakukan maka diperoleh alternatif lokasi yang lebih di prioritaskan adalah labuhan Ratu dengan bobot penilaian (0,406).
Kata kunci: Pengambilan Keputusan, Pemilihan Lokasi usaha, Strategi lokasi usaha, Analytical Hierarchy Process
Perputaran Perputaran Modal Kerja, Likuiditas dan Leverage, Memacu Rentabilitas Perusahaan
Authors: Buniarto Edwin Agus 
Published: September 2021

Abstract

This study aims to determine the effect of working capital turnover, liquidity and solvency on profitability in food and beverage sub-sector companies in the Indonesian Capital Market for the 2016-2020 period. Working capital turnover variable is calculated using the Working Capital Turnover ratio, liquidity is measured using Current Ratio, solvency is measured using Debt to Assets Ratio and Profitability is measured using Return on Assets.
This type of research is quantitative using the classic assumption test, multiple linear regression analysis and partial test. The sampling technique uses the purposive sampling method. The results of the analysis that have been done, show that the working capital turnover, liquidity and solvency significantly influence the profitability of the company.
This is evidenced by the results of correlation analysis which shows the value of r = 0.831 which means there is a strong relationship between working capital turnover, liquidity and solvency to profitability. Partially, each independent variable significantly influences profitability.

Keywords: Working Capital Turnover, Liquidity, Solvency, Return on Assets
IMPLEMENTASI ABSEN FINGERPRINT Di SMK YAPURA 1 BOGOR
Authors: Prayudha Ridhan Anggihadi , Afrianto Yuggo 
Published: September 2021

<div>Seiring dengan perkembangan teknologi maka dilakukan pengembangan berbagai aplikasi yang dapat merubah sistem kerja Mesin absen sidik jari atau fingertprint adalah suatu mesin yang digunakan untuk mengetahui dan mendata kehadiran dengan mengidentifikasi tekstur sidik jari sebagai media pendataan Mesin absensi tidak dapat berdiri sendiri melainkan harus terkoneksi dengan sebuah jaringan komputer Absensi sidik jari digital yang digunakan berbasis IP yang bergantung pada sistem komputer. IP di atur secara manual pada mesin absensi sidik jari digital dan pada saat penginstalan software absensi tersebut. Tujuan penelitian ini adalah membantu memantau kehadiran guru secara maksimal, membantu manage atau merekap absensi para guru menggunakan aplikasi fingerprint. Adapun manfaat yang diperoleh dari penelitian ini yakni meningkatkan kedisiplinan dan memudahkan absensi kehadiran guru dan siswa mempelajari proses absensi mulai dari scan sidik jari ke mesin fingerprint hingga pengiriman laporan ke pusat database absen. Metode analisi, implementasi dan pengujian. </div><div>Kata kunci : absensi, fingerprint</div><h1 style="margin-top: 4.35pt; margin-right: .2pt; margin-bottom: .0001pt; margin-left: 36.0pt; text-align: justify; line-height: 115%;"><span style="font-size: 11.0pt; line-height: 115%; font-weight: normal; mso-bidi-font-weight: bold;" lang="id">Seiring dengan perkembangan teknologi maka dilakukan pengembangan berbagai aplikasi yang dapat merubah sistem kerja Mesin absen sidik jari atau fingertprint adalah suatu mesin yang digunakan untuk mengetahui dan mendata kehadiran dengan mengidentifikasi tekstur sidik jari sebagai media pendataan Mesin absensi tidak dapat berdiri sendiri melainkan harus terkoneksi dengan sebuah jaringan komputer</span><span style="font-size: 11.0pt; line-height: 115%; font-weight: normal; mso-bidi-font-weight: bold;" lang="id">Absensi sidik jari digital yang digunakan berbasis IP yang bergantung pada sistem komputer. IP di atur secara manual pada mesin absensi sidik jari digital dan pada saat penginstalan software absensi tersebut. Tujuan penelitian ini adalah membantu memantau kehadiran guru secara maksimal, membantu manage atau merekap absensi para guru menggunakan aplikasi fingerprint. Adapun manfaat yang diperoleh dari penelitian ini yakni meningkatkan kedisiplinan dan memudahkan absensi kehadiran guru dan siswa mempelajari proses absensi mulai dari scan sidik jari ke mesin fingerprint hingga pengiriman laporan ke pusat database absen. Metode analisi, implementasi dan pengujian. </span></h1><h1 style="margin-top: 4.35pt; margin-right: .2pt; margin-bottom: .0001pt; margin-left: 36.0pt; text-align: justify; line-height: 115%;"><span style="font-size: 11.0pt; line-height: 115%;" lang="id">Kata kunci :</span><span style="font-size: 11.0pt; line-height: 115%; font-weight: normal; mso-bidi-font-weight: bold;" lang="id"> absensi, fingerprint <em style="mso-bidi-font-style: normal;"></em></span></h1>
RANCANG BANGUN SISTEM REKOMENDASI PEMILIHAN WEDDING ORGANIZER MENGGUNAKAN METODE SIMPLE ADDITIVE WEIGHTING
Authors: Agusti Astri Yolanda , Br.Ginting Novita , Primasari Dewi 
Published: September 2021

<p>Pernikahan merupakan suatu acara sakral yang diselenggarakan dengan persiapan yang sangat matang. Demi memaksimalkan waktu dan biaya, beberapa calon pengantin menggunakan jasa sebuah <em>Wedding Organizer. Wedding Organizer</em> merupakan suatu jasa yang memberikan pelayanan khusus secara pribadi yang bertujuan untuk membantu calon pengantin dan keluarga calon pengantin dari mulai perencanaan sampai tahap pelaksanaan. Untuk membantu calon pengantin melakukan pemilihan <em>Wedding Organizer</em> diperlukan perhitungan khusus untuk masing-masing alternatif dengan kriteria yang dimiliki. Maka dari itu diperlukan sistem rekomendasi yang dapat memberikan solusi pemilihan <em>wedding</em> <em>organizer</em> dengan metode perhitungan <em>Simple Additive Weighting </em>(SAW). Konsep dasar metode <em>Simple Additive Weighting </em>(SAW)<em> </em>adalah mencari penjumlahan terbobot dari rating kinerja pada setiap alternatif pada semua atribut Metode pengembangan sistem yang digunakan penenilitian ini adalah <em>Waterfall</em>, dimana terdapat beberapa proses yang berjalan secara berurutan yaitu <em>Analysis</em>, <em>Design</em>, <em>Code</em>, dan <em>Test. </em>Hasil penelitian ini adalah sebuah sistem rekomendasi pemilihan <em>Wedding Organizer</em> menggunakan metode <em>Simple Additive Weighting </em>(SAW)<em> </em>dengan perancangan sistem menggunakn model UML yang menghasilkan <em>Use Case Diagram, Activity Diagram, Sequence Diagram, Class Diagram, Deployment Diagram, Design Database, </em>dan <em>Design Interface.</em></p>
ANALISIS DESKRIPTIF QUARTER-LIFE CRISIS PADA LULUSAN PERGURUAN TINGGI UNIVERSITAS KATOLIK MUSI CHARITAS
Authors: Riyanto Agustinus , Arini Diana Putri 
Published: September 2021

ABSTRACT: QUARTER-LIFE CRISIS DESCRIPTVE ANALYSIS ON COLLEGE GRADUATES OF KATOLIK MUSI CHARITAS UNIVERSITY Quarter-life crisis is a phenomenon of anxiety over the age of 20, which is the transition from late adolescence to adulthood. The research objective was to reveal the quarter-life crisis phenomenon in freshmen graduates. Research participants were 115 graduate students for the 2019 and 2020 periods from the Catholic University of Musi Charitas. The analysis technique used is statistical description analysis, data collection using a quarter-life crisis scale which is given online using WhatsApp Group. Based on the research results, it was found that 86% of students experienced a quarter-life crisis. Based on the results of interviews, the anxiety experienced by students was related to careers which were considered difficult to find suitable jobs and feelings of being trapped with jobs because of financial needs. This research is a preliminary study to analyze the quarter-life crisis. It is hoped that this research can be continued to look at various other variables that are thought to have contributed to the quarter-life crisis. Keywords: quarter-life crisis, anxiety, college graduates Quarter-life crisis adalah fenomena kecemasan di usia 20 tahun keatas yang merupakan transisi masa remaja akhir menuju masa dewasa muda. Tujuan penelitian adalah mengungkap fenomena quarter-life crisis pada mahasiswa baru lulus. Partisipan penelitian adalah 115 mahasiswa lulusan periode 2019 dan 2020 dari Universitas Katolik Musi Charitas. Teknik Analisis yang digunakan adalah analisis deskripsi statistika, pengumpulan data menggunakan skala quarter-life crisis yang diberikan secara daring menggunakan whatsapp group. Berdasarkan hasil penelitian ditemukan ada 86% mahasiswa yang mengalami quarter-life crisis. Berdasarkan hasil wawancara, kecemasan yang dialami mahasiswa berhubungan dengan karir yang dianggap sulit untuk mencari pekerjaan yang sesuai dan perasaan terjebak dengan pekerjaan karena kebutuhan finansial. Penelitian ini merupakan penelitian awal untuk menganalisa quarter-life crisis, harapannya penelitian ini dapat diteruskan untuk melihat berbagai variabel lain yang diduga berkontribusi terhadap quarter-life crisis. Kata kunci : quarterlife-crisis, kecemasan, lulusan perguruan tinggi
HUBUNGAN ANTARA INTENSITAS PENGGUNAAN MEDIA SOSIAL INSTAGRAM DENGAN HARGA DIRI
Authors: Dalila Firda , Putri Asri Mutiara , Harkina Prida 
Published: September 2021

ABSTRACT: RELATIONSHIP BETWEEN THE INTENSITY OF INSTAGRAM SOCIAL MEDIA USAGE WITH SELF ESTEEM Self-esteem is formed by interactions with other people. At present, social interaction can not only be done in the real world but can also be done in the virtual world, through social media such as Instagram. This study aimed to determine the relationship between the intensity of Instagram social media usage and self-esteem. This research is a quantitative study with a correlational design. The sample in this study were 205 undergraduate students of Malahayati University, aged between 17 to 25 years. The data in this study were obtained using an Instagram social media intensity usage questionnaire and a self-esteem scale. The results of data analysis using Spearman's rho show that there is a significant positive relationship between intensity of Instagram social media usage and self-esteem. Keywords: Intensity of Social Media Usage, Instagram, Self Esteem Harga diri terbentuk dari interaksi dengan orang lain. Saat ini untuk melakukan interaksi sosial tidak hanya dapat dilakukan didunia nyata namun juga dapat dilakukan didunia maya, melalui media sosial seperti instagram. Penelitian ini bertujuan untuk mengetahui hubungan antara intensitas penggunaan media sosial instagram dengan harga diri. Penelitian ini merupakan penelitian kuantitatif dengan desain korelasional. Sampel dalam penelitian ini adalah 205 mahasiswa S1 Universitas Malahayati, berusia antara 17 sampai 25 tahun. Data dalam penelitian ini diperoleh menggunakan kuesioner intensitas penggunaan media sosial instagram dan skala harga diri. Hasil analisis data menggunakan Spearman’s rho menunjukkan bahwa terdapat hubungan positif yang signifikan antara intensitas penggunaan media sosial instagram dengan harga diri. Kata Kunci: Intensitas Penggunaan Media Sosial, Instagram, Harga Diri
Upaya Meningkatkan Hasil Belajar Passing Bawah Bola Voli	Dengan Pendekatan Pembelajaran Massed Practice
Authors: Imistauma Ahmad , Kusuma Lalu Sapta Wijaya , Imran Ali 
Published: September 2021

The following reaserch intends for intensifying volleyball lower passing skills at 1st grade students in SMP Satu Atap 3 Pringgasela. This kind of Classroom Action Reaserch (CAR) aims to fix and increase learning quality and recover teachers to solve several learning problems at school. This reaserch uses Practice Massed Method in 2 Cycles that consists a plan, implementation, action, observation, and evaluation/reflection. The samples in this reaserchis 12 students from 1st grade. The results show that volleyball lower passusing massed practice method at 1st grade of SMP Satu Atap 3 Pringgasela increased from cycle 1 got 5 students (41.6%) passed and 7 students (58.3%) unpassed. And from cycle 2 shows 9 students (75%) passed and 3 students (25%) unpassed. According to the result can be stated an incrase occurs 33% in cycle 1 and 2.
Determinants of Capital Structure Using Profitability as Moderating in Indonesia’s Property and Real Estate Firms
Authors: Tamba Cecilia Anggie O. , Purwanto Purwanto 
Published: September 2021

The research aim is to examine determinant factors of Indonesia's property and real estate firms capital structure listed in the Indonesia Stock Exchange. This is a quantitative research which taken 72 observation data from 12 companies audited financial statement and fulfilled certain criteria. Processing through classical assumption tests and multivariate analysis with the help of the EViews 10 software instrument. The results show that tangibility assets, business risk, and firm size have a significant influence on capital structure partially, but sales growth and liquidity have insignificant. The determination coefficient is 42.83% and the proportion is included in the strong criteria. Profitability as a moderating variable weakens the effect of business risk but strengthens the effect of firm size on the debt to equity ratio, further determining the company's ability to pay off its debt which is of great concern to investors and creditors. Furthermore, as a consideration for choosing the composition of a good funding decision in Indonesia.
Elizabeth Bishop and Audre Lorde: Two Views of ‘Florida’ in the Global South Atlantic
Authors: Campbell Marvin 
Published: September 2021

This chapter investigates how the transnational crossings Elizabeth Bishop launched from the peninsular Florida and its Key into Haiti, Mexico, Aruba, and most famously, Brazil, across North & South, Questions of Travel and Geography III correspond to an analogous geographical arc on the part of Audre Lorde, in which the Southeastern United States, Oaxaca, Mexico, and the Virgin Islands inform an equally fluid and indeed oceanic space from her work of the 1980s onward, when Lorde began spending significant time in the Virgin Islands. As Bishop sought to ‘do more’ with Key West and its environs in than modernist predecessors like Wallace Stevens and Hart Crane by employing this island to make investments in gender, race, nation, and class, Audre Lorde brought racial and sexual difference to the fore of this liminal crossing across national borders and boundaries, hybridizing her own better documented investments in Yoruba myth with a trans-American consciousness lodged squarely in not only the Caribbean and the Southeast, but in Oaxaca, Mexico and the Southwest. Such a remapping reveals two outsider poets who stand at the center of a literary formation where twentieth century American and African-American poetics converge and clash.
Introduction: Milestones in the History of the Twentieth-Century Press
Authors: Bingham Adrian 
Published: September 2021

This introductory chapter offers a new interpretation of twentieth century British press history by examining the changing ways in which owners, editors and journalists sought to address the British public in five milestone years – 1903, 1938, 1969, 1986 and, more briefly, 2011. Each section offers a brief overview of the industry at each of these crucial moments, before considering how the press tried to adapt both to new political, social and commercial opportunities, and to the challenges of the shifting media landscape. The central focus is on the most widely circulating and influential national (usually London-based) daily newspapers as a way of exploring some of the key trajectories of the wider industry.