bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vers une écologisation de la gouvernance de la santé
Authors: Blanc Nathalie 
Published: September 2021

Cet article traite de l’évolution de la relation entre la nature et l’environnement urbain au cours des XIX e et XX e siècles, et même jusqu’au XXI e siècle en Europe et aux États-Unis, une relation qui a été principalement abordée en termes de santé publique. L’aménagement de l’espace et les règles d’urbanisme ont longtemps été les outils d’un engagement politique s’intéressant à toutes les dimensions de la vie afin de surveiller et contrôler les atteintes qui pourraient lui être portées, et in fine de la préserver. La prise en compte des dimensions environnementales dans les politiques territoriales de santé conduit à revoir les liens aménagement/nature ainsi que le rôle des différents acteurs impliqués dans les politiques de santé.
Le principe d’analogie en littérature comparée et l’unicité de l’œuvre
Authors: Franco Bernard 
Published: September 2021

Le point de départ de la démarche comparative semble être la ressemblance. Plus généralement, l’analogie est à la fois principe créateur et modalité de lecture d’une œuvre : on écrit d’après une littérature existante, on lit d’après ses lectures précédentes. Néanmoins, le sens propre à une œuvre et qui garantit son unicité se dégage de la différence. Par l’étude des parallèles, qui se distingue de celle des dettes, des sources et de tout type de dérivation, la poétique comparée, derrière le constat de l’analogie, tire précisément l’interprétation des œuvres de l’analyse des différences.
Chinese Philosophical Foundation of the Variation Theory of Comparative Literature
Authors: Wang Chao 
Published: September 2021

La théorie des variations a suscité un grand intérêt dans les études internationales sur la littérature comparée ; il demeure néanmois un certain espace pour une exploration et un développement plus poussés. L’élaboration théorique de la littérature comparée repose en général sur des sources philosophiques sous-jacentes. Par exemple, les études d’influence issues de l’école française reposent sur la philosophie positiviste, et les études de parallèles propres à l’école américaine sont fondées sur l’herméneutique et l’esthétique de la réception. De fait, une théorie des variations est introduite dans le contexte académique chinois. Peut-on alors identifier son fondement philosophique chinois ? Dans l’ensemble, il ne provient pas d’une école de philosophie moderne ou contemporaine, mais il est enraciné dans les idées de variation qui prennent leur cohérence dans les discours philosophiques chinois anciens, tels que « Trois connotations de changements » (易 之 三名). Ces expressions philosophiques ont fourni une matière idéologique et un socle méthodologique pour la théorie des variations.
Photographic Assessment of Intermittent Exotropia Using a Translucent Cover
Authors: Chung Seung Ah , Rhiu Soolienah , Park Aram , Yu Jaeeun 
Published: September 2021

Purpose:
To evaluate the validity of the photographic assessment with a translucent cover that is clinically available for the evaluation of intermittent exotropia.

Methods:
Photographs of 270 patients who cooperated for the prism and alternate cover test (PACT) were reviewed. Full-face images were obtained with a digital camera while a translucent cover was placed in front of either eye. The change in distance from the medial canthus to the nasal limbus with occlusion was measured and the photographic angle was estimated by three independent ophthalmologists based on representative photographs. These two measurements were correlated with the angle measured using the PACT, and clinical features related to the discrepancy between the photographic angle and the angle measured with the PACT were determined.

Results:

Patients with intermittent exotropia of 27.0 ± 6.1 prism diopters (PD) showed a 4.5 ± 3.3 mm exodrift and an estimated angle of 29.0 ± 4.3 PD on the photographs with occlusion. The exodrift distance and photographic angle were positively correlated with the angle of PACT (
r
= 0.256,
P
< .001 and
r
= 0.546,
P
< .001, respectively). Of the 47 patients with a discrepancy of greater than 8 PD, 38 patients (80.9%) were regarded as having a photographic angle that was larger than the angle of PACT, which was more common in older patients, in those with a small distance angle, and when taking off the spectacles.

Conclusions:
Photographs with a translucent cover can reveal the latent components of intermittent exotropia. However, the photographic angle might differ from the real angle, particularly in older patients with a small angle and with the spectacles off.

[
J Pediatr Ophthalmol Strabismus
. 2021;58(5):331–338.]
Reduced-form setting under model uncertainty with non-linear affine intensities
Authors: Biagini Francesca , Oberpriller Katharina 
Published: September 2021

<p style='text-indent:20px;'>In this paper we extend the reduced-form setting under model uncertainty introduced in [<xref ref-type="bibr" rid="b5">5</xref>] to include intensities following an affine process under parameter uncertainty, as defined in [<xref ref-type="bibr" rid="b15">15</xref>]. This framework allows us to introduce a longevity bond under model uncertainty in a way consistent with the classical case under one prior and to compute its valuation numerically. Moreover, we price a contingent claim with the sublinear conditional operator such that the extended market is still arbitrage-free in the sense of “no arbitrage of the first kind” as in [<xref ref-type="bibr" rid="b6">6</xref>].	</p>
Les écrits de la discorde. Le procès de Belle-Île et la fabrique du cartulaire de Quimperlé (vers 1110-1130)
Authors: Queney Lucile 
Published: September 2021

Composé à la fin des années 1120, le cartulaire de l’abbaye de Quimperlé est fortement marqué par le procès relatif à la possession de Belle-Île-en-Mer, gagné par l’abbaye cornouaillaise contre celle de Redon, une dizaine d’années plus tôt. La violence exprimée par le rédacteur quimperlois dans son « Opuscule » est révélatrice d’un souvenir toujours vif qui est à l’origine de ce cartulaire composite, rassemblant tant l’histoire du monastère que les diverses chartes attestant de ses possessions. Revendiqué comme une protection juridique, le manuscrit répond aussi, dans ses choix d’organisation et de sélection, à des enjeux mémoriels et de gestion des biens de l’abbaye. Le conflit pour Belle-Île est central dans cette affaire et il atteste de la mobilisation des réseaux de soutien des deux abbayes pour appuyer leur légitimité. Cette concurrence s’inscrit dans les mutations sociales et ecclésiales de ce début de xiie siècle, ce qui explique l’implication, dans ce conflit très local, du pape et du duc de Bretagne.
Un tabellionage princier : les tabellions du comté de Dunois au xve siècle
Authors: Mouftiez Vincent 
Published: September 2021

Seigneurie princière, le comté de Dunois (créé en 1439 au profit de Jean, bâtard du duc d’Orléans) fut le siège d’un tabellionage dont une centaine de registres ont été conservés. Leur étude permet d’étudier le travail quotidien des tabellions, ces notaires du nord de la France, qui ont été l’objet d’un renouveau historiographique au cours des dernières années. Ils témoignent de l’uniformité des pratiques du tabellionage dans le Nord du royaume au xve siècle et nous permettent de connaître les méthodes de travail (les jours, les lieux), les origines, les activités économiques et l’intégration dans la société des tabellions. L’étude d’un cas particulier montre le parcours professionnel d’un homme, à partir de l’échelon le plus bas (clerc du bailliage) jusqu’au poste de tabellion. L’étude de son patrimoine foncier et de ses alliances matrimoniales illustre son ascension sociale : il devient membre de l’élite dunoise et intègre la noblesse locale.
Analyses of the gut bacteriomes of four important Drosophila pests
Authors: Lin Qingcai , Zhai Yifan , Chen Hao , Qin Dongyun , Zheng Li , Gao Huanhuan 
Published: September 2021

AbstractSeveral Drosophila species (Diptera: Drosophilidae) have become serious economic pests of berry and soft-skinned stone fruits around the world. Prominent examples are Drosophila suzukii (Matsumura), D. melanogaster (Meigen), D. hydei (Sturtevant), and D. immigrans (Sturtevant). Information on the biology and ecology of Drosophila is important for a better understanding of these important fruit pests and, ultimately, for fruit protection. In this study, the gut bacteriomes of these four Drosophila species were surveyed and the differences among bacterial communities were characterised. The 16S rRNA genes of gut microbes were sequenced by Illumina MiSeq technology (Illumina, San Diego, California, United States of America), followed by α-diversity and β-diversity analyses. The results show that bacteria of the family Enterobacteriaceae (Kluyvera and Providencia; phylum Proteobacteria) dominated all four Drosophila species. Specific dominant gut bacterial communities were found in each Drosophila species. The dominant families in D. melanogaster and D. suzukii were Enterobacteriaceae, Comamonadaceae, and Acetobacteraceae. In the intestine of D. hydei, Enterobacteriaceae had a proportion of 56.99%, followed by Acetobacteraceae, Spiroplasmataceae, and Bacillales Incertae Sedis XII. In D. immigrans, besides Enterobacteriaceae, Alcaligenaceae, Flavobacteriaceae, Xanthomonadaceae, Comamonadaceae, and Sphingobacteriaceae also had high relative abundance. These data expand current knowledge about the putative function related to gut microbes – for example, the metabolism of carbohydrates, amino acids, inorganic ions, lipids, and secondary metabolites. This knowledge provides a basis for further metatranscriptomic and metaproteomic investigations.
The National Chest Pain Centers Program: Monitoring and Improving Quality of Care for Patients with Acute Chest Pain in China
Authors: Xiang Ding-Cheng , Jin Yin-Zi , Fang Wei-Yi , Su Xi , Yu Bo , Wang Yan , Wang Wei-Min , Wang Le-Feng , Yan Hong-Bing , Fu Xiang-Hua , Zheng Zhi-Jie , Labresh Kenneth A. , Huo Yong , Ge Jun-Bo 
Published: September 2021

Abstract

Background:
The National Chest Pain Centers Program (NCPCP) is the largest nationwide, hospital-based, multifaceted, continuous quality improvement initiative, which aims to monitor and improve the quality of care for patients with acute chest pain. The accreditation of the standardized chest pain center is central to the project. The purpose of establishing chest pain centers is to develop a mechanism for “sending acute chest pain patients to a hospital with capabilities for the best treatment in the shortest time possible.”

Objectives:
This study aims to evaluate the effectiveness and implementation of the chest pain center accreditation and to identify factors that may influence its implementation in local settings.

Study Design and Methods:
Hospitals that have been accredited between January 2016 and September 2020 will be recruited in this study. We will conduct a self-controlled retrospective cohort study by comparing the care performance before, during, and after the accreditation. Measures for care performance will be selected based on the American College of Cardiology/American Heart Association clinical practice guidelines, which will be divided into prehospital processes, in-hospital processes, and in-hospital outcomes. For the implementation of the chest pain center accreditation, we will use a modified reach, effectiveness, adoption, implementation, maintenance (RE-AIM) framework to investigate the implementation process, and the consolidated framework for implementation research will be used to identify factors that emerge within the local context and influence the implementation fidelity and feasibility.

Progress to Date:
As of September 2020, there were 4,621 hospitals that registered the NCPCP, of which 1,507 hospitals were accredited. A total of 5,228,973 patients with a primary diagnosis on admission were enrolled from the registered hospitals, among which 34.6% were acute coronary syndromes.

Conclusions:
In this study, we proposed recommendations for improving the implementation of chest pain center accreditation, which will improve the quality of care for patients with acute chest pain and promote the sustainable development of chest pain center.

Trial Registration:
ClinicalTrials.gov, NCT04014972, registered July 10, 2019
Evaluation of two conservative different treatment protocols for symptomatic proximal deep caries management in molar teeth; an 18-month clinical report
Authors: Sherwood I. Anand , Divyameena B. , Ramyadharshini T. , Subashri V. , Banerjee Avijit 
Published: September 2021

Aim:
The primary aim of this clinical trial was to observe the clinical success in conservative management of symptomatic deep proximal caries in permanent molar teeth with two treatment pulpotomy with Biodentine and indirect pulp capping with calcium hydroxide.

Materials and Methods:
A total of 71 patients who reported to department for the management of symptomatic proximal deep carious lesions in molar teeth participated in the trial. Posttreatment clinical success at 18 months was defined as asymptomatic teeth positively responding to cold pulp sensibility test (only in indirect pulp capping) and absence of periapical infection. Chi-squared test and Kaplan–Meier survival analysis were done.

Results:
Chi-squared test revealed no significant association between pulp status and posttreatment follow-up in both the treatment groups. Kaplan–Meier survival analysis showed mean survival of pulpotomy procedure for moderate and ambiguous pulp as 66.16 and 67.77 weeks, respectively, with no significant difference for two different pulp statuses. In indirect pulp capping procedure, there was significant difference (P = 0.038) (Log-rank Mantel-Cox) between the two pulp status category with moderate pulpitis having mean survival period of 69.27 weeks and ambiguous pulp with 42.83 weeks.

Conclusion:
Pulpotomy with Biodentine yielded better results than compared to indirect pulp capping.
Comparative evaluation of pull-out bond strength of fiber post using different luting cements in endodontically treated teeth
Authors: Singh Neha , Garg Ashima , Mittal Rakesh 
Published: September 2021

Aim:
This study was aimed to evaluate and compare the pull-out bond strength of fiber post using glass ionomer cement (GIC), resin-modified glass ionomer cements (RMGIC), self-etch adhesive resin cement, and self-adhesive resin cement in endodontically treated teeth.

Materials and Methods:
Forty single-rooted teeth with single canal were decoronated, endodontically treated, post space were prepared and divided into four groups (n = 10) based on the cement used for luting the fiber post. Group 1: GIC, Group 2: RMGIC, Group 3: Self etch adhesive resin cement, Group 4: Self-adhesive resin cement. Pull-out test was evaluated for the prepared samples. Statistical analysis was performed using analysis of variance and Tukey's test (P = 0.05).

Results:
The mean pull-out bond strength of Group 4 was statistically higher than Group 1,2 and 3. Group 1 showed the least bond strength among all the groups.

Conclusion:
Within the limitation of this study, self-adhesive resin cements provide better bond strength of fiber post to root canal compared to self-etch adhesive resin cement and glass ionomer based cements.
Comparative evaluation of sealing ability of three bioactive obturation materials
Authors: Singla Meenu G , Panghal Sakshi 
Published: September 2021

Aim:
The aim of this study was to evaluate and compare the sealing ability of three obturating materials used with single-cone technique: C Point/Endosequence BC sealer, gutta-percha/Endoseal MTA and gutta-percha/GuttaFlow bioseal using bacterial leakage model with Enterococcus faecalis.

Materials and Methods:
Seventy-six extracted human single-rooted mandibular premolars with straight canals prepared using Hyflex CM up to 45/04 and assigned to 3 experimental groups according to the root canal filling material as Group A - C Point/Endosequence BC sealer; Group B - guttapercha/Endoseal MTA; Group C - guttapercha/GuttaFlow bioseal. Split-chamber bacterial leakage model was prepared and microleakage analysis was made every 24 h for up to 9 weeks. The presence of E. faecalis was confirmed by light microscopy and Gram staining.

Results:
A survival analysis was performed using Kaplan–Meier plots and a log-rank test and it was found that Group A showed the best apical seal followed by Group C and then Group B at the end of the observational period. The difference in bacterial leakage among Group A and C versus Group B was statistically significant (P < 0.05), but there was no significant difference between Group A and Group C.

Conclusion:
C Point/Endosequence BC sealer and GP/Guttaflow bioseal sealer has shown better apical seal with single-cone technique as compared to GP/Endoseal MTA.
Comparison of fracture resistance of endodontically treated mandibular first molars restored with different reinforcing materials with and without cusp capping
Authors: Singh Vaishnavi J , Mantri Shivkumar P , Paul Bonny , Dube Kavita A , Gupta Nishikumari , Ghosh Sayantani 
Published: September 2021

Aim:
This study aims to estimate and compare the fracture resistance of endodontically treated mandibular first molar restored with reinforced composite resin or cusp capping.

Materials and Methods:
Seventy-five freshly extracted intact mandibular molars were randomly divided into five groups. The teeth were embedded vertically into the self-cure acrylic lined with elastomeric impression material to a level 1 mm apical to the cement-enamel junction. Group 1 included intact teeth. After access preparation in Groups 2–5, canals were negotiated with 10 K file, cleaned shaped using K3XF NiTi rotary files, 17% Ethylenediaminetetraacetic acid, and 3% sodium hypochlorite. After drying, the canals were obturated with gutta-percha and Sealapex sealer. Group 2 teeth were restored using Cavit. In Groups 3–5, the access cavity floor was lined by resin-modified glass-ionomer cement. After etching, rinsing, and bonding, teeth were restored. Group 3 teeth with everX posterior as a base and 1.5 mm of occlusal nanohybrid composite. Group 4 teeth were restored with nanohybrid composite after bonding Interlig fiber circumferentially in the access cavity. In Group 5, after 2 mm cusp reduction, etching, and bonding, teeth were restored by cusp capping using nanohybrid composite. All specimens were subjected to a fracture test. The peak-load fracture value in Newton was recorded.

Results:
One-way analysis of variance test for intergroup comparison revealed a statistically significant difference between the groups (P = 0.011). Post hoc Tukey's test showed a significant difference (P = 0.005) between everX posterior and Cavit specimens. The Chi-square test results revealed that there is a significant difference (P = 0.0276) in the fracture pattern between the groups.

Conclusion:
It is concluded that restoration using short fiber-reinforced composite improved the fracture resistance of endodontically treated mandibular molars. Cusp-capped teeth exhibited more favorable fractures. The combined use of fiber-reinforced composite and capping the cusps using nanohybrid composite could be a viable option to restore molar favorably.
Evaluation of 18FDG PET-CT-positive mediastinal-hilar lymph nodes in extrathoracic malignancies by EBUS-TBNA; correlation of SUVmax, and short-axis diameter with the final diagnosis
Authors: Luthra Kunal , Singh Jyoti 
Published: September 2021

Introduction:
Intrathoracic lymph node metastasis from extrathoracic neoplasms are rare. Primary malignancies that metastasize to mediastinal-hilar lymph nodes are head and neck , carcinoma breast ,and genitourinary. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)/endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is currently the preferred modality for mediastinal lymph node sampling.

Methods:
Fifty seven patients with extrathoracic malignancies with maximum standardized uptake value (SUVmax) of mediastinal-hilar lymph nodes greater than or equal to 2.5 were taken up for EBUS-TBNA. The histo-cytopathological results obtained from EBUS-TBNA were compared with SUVmax value and short-axis diameter of a lymph node as noted on EBUS.

Results:
Out of 74 sampled nodes, 49 (66.2%) were benign and 25 (33.8%) were malignant. The SUVmax range of benign nodes was 2.8–13 as compared to 3–18 of malignant nodes. The size range of malignant and benign nodes were 8–35 mm and 8–30 mm, respectively. The mean size of abnormal nodes (metastatic + granulomatous) was 17.5 (8–35 mm) and the mean SUVmax was 9.1 (3.4–18), and it was a statistically significant difference when compared to reactive (normal) nodes. At SUVmax cut-off 7.5, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) were 78.5%, 81.2%, 84.6%, and 74.2%, respectively for detecting abnormal nodes. At 13 mm size cut-off, sensitivity, specificity, PPV, NPV were 75.5%, 65%, 75%, and 72%, respectively, for detecting abnormal nodes.

Conclusion:
The majority of mediastinal-hilar nodes with increased metabolic activity are benign in nature. Size and SUVmax are poor predictors of metastasis in tuberculosis endemic region. There should be a restrictive attitude toward invasive diagnostic testing for mediastinal-hilar nodes in extrathoracic malignancies.
Tacrolimus Therapeutic Drug Monitoring and Correlation with Clinical Events – A Single-Center Prospective Study
Authors: Prabhu Mayoor V. , Karopadi Akash Nayak , Subhramanyam Sreepada V. , Pai B. H. , Nayak K. S. 
Published: September 2021

Background:
Tacrolimus exposure is estimated by trough levels (C0). Recent studies suggest that C0 may not accurately reflect the area under the curve (AUC) and may not correlate with clinical events like acute rejection (AR) and nephrotoxicity.

Materials and Methods:
In an open, prospective, single-center study, 29 consecutive recipients of renal transplantation underwent C0 along with 2-h (C2), 4-h (C4), and 6-h (C6) estimation of blood tacrolimus levels by enzyme-linked immunosorbent assay, 72 h after initiation with tacrolimus or after a change in its dosage. AUC was estimated by trapezoidal method. C0, C2, C4, and C6 levels were correlated with the AUC.

Results:
Thirty-six AUC estimations were made over a 2-year period. The best correlate was C6. Correlation coefficients were C0 – 0.868, C2 – 0.788, C4 – 0.839, and C6 – 0.904. C6 values accounted for 79% of the variability of the AUC. Six patients experienced AR, with 5 having C0 within the target range. C6 values correlated best with AUC in these patients (C0 – 0.970, C2 – 0.833, C4 – 0.942, and C6 – 0.970). This was statistically significant. Three patients developed tacrolimus toxicity. In these patients, the correlation coefficients were C0 – 0.551, C2 – 0.556, C4 – 0.77, and C6 – 0.941. By regression analysis, we developed predictive equations. The equation AUC = 12.126 + 2.81 × C0 + 2.92 × C6 best predicted the AUC.

Conclusions:
Overall C6 levels were more predictive of the AUC, accurately predicting AR and nephrotoxicity. Incorporating C6 may improve tacrolimus therapeutic drug monitoring.