bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of temperature on the activity of the trigeminal nerve in the rat meningeal sheath
Authors: Fedorina A.I. , Gafurov O.Sh. 
Published: December 2021

Migraine is a debilitating neurological disorder that affects approximately 1 billion people worldwide. It is known that migraine is associated with the activity of the trigeminal nerve, therefore, many studies are aimed at studying changes in the activity of the meningeal nerve fibers. It is known that inflammatory processes accompanied by temperature rise are often accompanied by headaches. Therefore, we investigated the effect of temperature increase on trigeminal nerve activity. It turned out that temperature increase leads to a significant increase in the frequency of action potentials in the trigeminal nerve.
Key words: migraine, trigeminal nerve, cluster analysis, action potential.
Effect of combined action of arsenic and antimony compounds on renal function in the subchronic test
Authors: Shestakov N.A. , Aizman R.I. , Ogudov A.S. , Chuenko N.F. 
Published: December 2021

The study was conducted on male Wistar rats. We used 4 mathematically related series of doses prepared by sequential dilution of water from a man-made lake according to the scheme: arsenic: 0.15 - 0.05 - 0.016 - 0.0055, antimony: 0.68 - 0.227 - 0.075 - 0.025 mg/l. The animals were examined before inoculation (background), on days 40 and 90 of the experiment, taking into account the processes of cumulation of chemical elements in the kidneys. New data on the nature of nephrotoxic effects of arsenic and antimony in the long-term combined intake into the body of laboratory animals have been obtained.
Key words: water from a man-made lake, arsenic and antimony compounds, Wistar rats, nephrotoxicity.
Analysis of the content of nitric oxide (II) metabolites rats of different ages
Authors: Belova Y.I. , Yakovleva O.V. 
Published: December 2021

Nitrogen monoxide is a gas transmitter that is an important intermediary in many organ systems, especially in the central nervous system. Nitrogen monoxide is involved in the relaxation of smooth vascular muscles, activation of neurons and responsible for the cytotoxicity of macrophages. The study of change nitrogen oxide metabolite concentration helps to determine its effects on human and animal organs. The study was carried out on laboratory animals of different ages. We used a spectrophotometric method to determine the level of metabolites based on the reaction of nitrites to the Griss reagent. We noted that the maximum level of metabolites NO was observed in newborn animals at the age of 4 days. In addition, metabolite concentrations decreased gradually by 14-15 days of life, reaching a minimum of 30 days
Key words: nitrogen monoxide, rats, age, metabolites of nitrogen monoxide, spectrophotometry.
The relationship between the component composition of the body and the rate of aging of student youth
Authors: Bragina A.M. 
Published: December 2021

Were examined 120 young men and young women. The analysis of the component composition was carried out using bioimpedance analysis by the MEDASS device. The coefficient of the aging rate was calculated according to the formula of A.G. Gorelkina. A correlation was established between the components of body composition and the rate of aging. The probability of accelerated aging of the body increases in the presence of excess fat mass. 25% of young men and 18.3% of young women belong to the risk group with an increased content of adipose tissue and a reduced content of skeletal muscles.
Key words: aging, biological age, body component composition, students.
The role of K-channels in the formation of a nociceptive signal in the rat trigeminal nerve
Authors: Buglinina A.D. , Verkhoturova T.M. , Gafurov O.Sh. , Koroleva K.S. , Sitdikova G.F. 
Published: December 2021

The central problem of this work is to elucidate the mechanisms of pain in migraine and to establish the role of Kv channels in regulating the excitability of meningeal afferents of the trigeminal nerve that form a pain signal in migraine. The study was conducted on a preparation of an isolated rat skull. It was found that Kv-channel inhibitors 4-aminopyridine (100 microns and 1 mM) and tetraethylammonium (5mm) lead to an increase in the excitability of trigeminal nerve afferents, at the same time, this effect was partially removed by a nonsteroidal anti–inflammatory agent - naproxen, and was not sensitive to sumatriptan, a classic anti-migraine drug.
Key words: migraine, K-channels, trigeminal nerve, 4-aminopyridine, tetraethylammonium, naproxen, sumatriptan.
Prospects for digitalization of the environmental monitoring system
Authors: Viderker M.A. , Rassadina E.V. 
Published: December 2021

Currently, digitalization affects various sectors of the economy. The state plays a significant role in regulating digitalization. Digital transformation opens up great prospects for the ecology and nature management industry. The main advanced technologies that will allow the industry to reach a qualitatively new level are big data, the Internet of Things and artificial intelligence. The introduction of digital technologies and platform solutions into an integrated environmental monitoring system will allow to quickly carry out integrated collection, processing and analysis of data, forecasting and management decisions on environmental protection issues, and ensure the openness of data and decisions made.
Key words: digital technologies, digitalization, digital economy, ecology, nature management, environmental monitoring.
Personalized approach in optimizing the treatment of acute pancreatitis
Authors: Vlasov A.P. , Trofimov V.A. , Al-Kubaysi S.S. , Myshkina N.A. , Muratova T.A. , Umnov L.N. , Khachaturov M.Yu . 
Published: December 2021

In order to determine the effectiveness of the use of remaxol based on a personalized approach in patients with acute pancreatitis, based on the establishment of gene polymorphism of integrin beta-3 (T1565C, ITGB3), integrin alpha-2 (C807T, ITGA2), fibrinogen (G(-455)A, FGB) and plasminogen activator inhibitor (5G(-675)4G, SERPINE1), a study of 84 patients with acute pancreatitis of varying severity was conducted. As a result of the study, it was proved that in order to increase the effectiveness of treatment of patients with severe acute pancreatitis upon admission, in addition to clinical, laboratory and instrumental studies, it is necessary to conduct genetic testing of the genotypes of the polymorphism of the GPIIa gene (T1565C), ITGA2 (C807T), FGB (G(-455)A) and SERPINE1 (5G(-675)4G) to develop a personalized approach in the treatment of this severe category of patients.
Key words: acute pancreatitis, genotype, DNA diagnostics, genetic testing of genotypes, personalized medicine.
The effect of mixed rot from the present tinder (Fomes fomentarius (L.:Fr.) Gill.) on the accumulation of heavy metals in the hanging birch (Betula pendula Roth.)
Authors: Gnusarev S.S. , Mitrofanova N.A. , Churakov B.P. 
Published: December 2021

A study was conducted on the effect of mixed rot from the present tinder on the accumulation of heavy metals (copper, zinc, nickel, cadmium, lead, cobalt, iron) by hanging birch
Keywords: real tinder, mixed rot, heavy metals, hanging birch.
Morphofunctional assessment of platelet activity correction in hyperbaric blood oxygenation
Authors: Goriachaia M.N. , Altynbaeva E.N. , Ruzov V.I. , Slobodnyuk Н.А. 
Published: December 2021

100 patients with functional class II-III exertional angina were examined. The subjects underwent a 10-day course of hyperbaric oxygenation (HBO) in the 1.2 ATA mode for 40 minutes, against the background of standard therapy for coronary heart disease (IHD). Before and after HBO, the platelet link of hemostasis and the elastic properties of the platelet membrane were assessed. Assessment of the effect of the HBO course on the functional state of platelets, depending on their aggregation activity, showed that in patients with initially normal platelet aggregation, there is a tendency to a decrease in spontaneous aggregation, in contrast to patients with initial hypoaggregation, HBO promoted a significant increase in spontaneous aggregation. The use of a 10-day course of HBO was accompanied by a reaction of reducing the elasticity of the platelet biomembrane.
Key words: aggregation; atomic force microscopy; platelet membrane; hyperbaric oxygenation.
Sexual dimorphism in the physical development of boys and girls of the northern region with an established dysplastic phenotype
Authors: Ilyushenko N.A. , Gainutdinova Yu.O. , Eskindyrova Z.B. , Ragozina O.V. , Shevnin I.A. , Jafarova B.Z. 
Published: December 2021

The article analyzes the data of an anthropometric and somatotypological study of 164 boys and 93 girls of the northern region, different sexual somatotypes with different severity of signs-phenes of undifferentiated connective tissue dysplasia. It was found that 44% of boys and 22% of girls with d, according to sexual somatic differentiation, correspond to the biological sex, 34% of boys and 53% of girls have mild gender dysplasia in the form of mesomorphy, and 19% of boys and 21% of girls have signs of sex inversion. Undifferentiated connective tissue dysplasia affects the severity of morphotypological differences between sexual somatotypes and the appearance of signs of gracialization within them.
Key words: northern region, adolescence, sexual dimorphism, undifferentiated connective tissue dysplasia.
Large-size (1.7 × 1.7 mm2) β-Ga2O3 field-plated trench MOS-type Schottky barrier diodes with 1.2 kV breakdown voltage and 109 high on/off current ratio
Authors: Otsuka Fumio , Miyamoto Hironobu , Takatsuka Akio , Kunori Shinji , Sasaki Kohei , Kuramata Akito 
Published: December 2021

Abstract
We fabricated high forward and low leakage current trench MOS-type Schottky barrier diodes (MOSSBDs) in combination with a field plate on a 12 μm thick epitaxial layer grown by halide vapor phase epitaxy on β-Ga2O3 (001) substrate. The MOSSBDs, measuring 1.7 × 1.7 mm2, exhibited a forward current of 2 A (70 A cm−2) at 2 V forward voltage and a leakage current of 5.7 × 10–10 A at −1.2 kV reverse voltage (on/off current ratio of > 109) with an ideality factor of 1.05 and wafer-level specific on-resistance of 17.1 mΩ · cm2.
Impact of graphene-molecular interaction on collective orientation barrier for organic film growth
Authors: Nagai Sae , Inaba Yuta , Nishi Toshio , Tomiya Shigetaka 
Published: December 2021

Abstract
The temperature-dependent molecular orientation variation of pentacene (PEN) on a graphene-covered substrate (PEN/Gr) was investigated via p-polarized multiple-angle incidence resolution spectrometry (pMAIRS). The temperature regime of the orientation transition of PEN/Gr was different from that of PEN/SiO2. The collective orientation barrier (COB), an energy barrier that molecules need to overcome to form a standing orientation, was estimated via pMAIRS. Consequently, the COB of PEN/Gr was found to be 10 times larger than that of PEN/SiO2. This indicated that the COB is valuable for understanding the effect of substrate interaction on molecular orientation.
Theoretical analysis of the inverse Edelstein effect at the LaAlO3/SrTiO3 interface with an effective tight-binding model: important role of the second d

xy
subband
Authors: Arai Shoma , Kaneta-Takada Shingo , Duc Anh Le , Tanaka Masaaki , Ohya Shinobu 
Published: December 2021

Abstract
The two-dimensional electron gas formed at interfaces between SrTiO3 and other materials has attracted much attention since extremely efficient spin-to-charge current conversion has been recently observed at these interfaces. This has been attributed to their complicated quantized multi-orbital structures with a topological feature. However, there are few reports quantitatively comparing the conversion efficiency values between experiments and theoretical calculations at these interfaces. In this study, we theoretically explain the experimental temperature dependence of the spin-to-charge current conversion efficiency using an 8 × 8 effective tight-binding model considering the second d

xy
subband, revealing the vital role of the quantization of the multi-band structure.
Hubungan Kekuatan Otot Lengan terhadap Keterampilan Shooting Free Throw dalam Permainan Bola Basket pada Siswa Ekstrakurikuler SMP Negeri 6 Kota Sukabumi
Authors: Mulyo Akbar chandra 
Published: December 2021

Skripsi Jurusan Pendidikan Jasmani Kesehatan dan Rekreasi Fakultas Keguruan dan Ilmu Pendidikan Universitas Muhammadiyah Sukabumi.
Peneliti ini di latar belakangi oleh keadaan shooting free throw yang masih kurang dari yang di harapkan di ekstrakurikuler SMP Negeri 6 Kota Sukabumi, oleh karena itu penulis ini bertujuan untuk mengetahui hubungan antara kekuatan otot lengan dengan keterampilan shooting free throw.
Penelitian ini merupakan penelitian korelasi, dengan menggunakan metode kuantitatif, variabel yang digunakan dalam penelitian ada dua variabel, dengan variabel bebas dalam penelitian ini adalah kekuatan otot lengan X sedangkan variabel terikat dalam penelitian ini adalah Shooting free throw Y. Populasi dalam penelitian ini adalah siswa ekstrakurikuler bola basket dengan menggunakan sempel jenuh yang berjumlah 16 orang. Teknik pengumpulan data yang digunakan adalah tes. Teknik analisis data yang digunakan yaitu uji korelasi dan uji signifikan dengan taraf signifikasi 5%. Dalam proses penghitungan data menggunakan bantuan computer program SPSS 23.
Hasil penelitian menunjukan adanya hubungan yang signifikan antara variabel x dengan variabel y atau kekuatan otot lengan dengan shooting free throw di ekstrakurikuler SMP Negeri 6 Kota Sukabumi.
Phytool, a ShinyApp to homogenise taxonomy of freshwater microalgae from DNA barcodes and microscopic observations
Authors: Canino Alexis , Bouchez Agnès , Laplace-Treyture Christophe , Domaizon Isabelle , Rimet Frédéric 
Published: December 2021

Methods for biomonitoring of freshwater phytoplankton are evolving rapidly with eDNA-based methods, offering great complementarity with microscopy. Metabarcoding approaches have been more commonly used over the last years, with a continuous increase in the amount of data generated. Depending on the researchers and the way they assigned barcodes to species (bioinformatic pipelines and molecular reference databases), the taxonomic assignment obtained for HTS DNA reads might vary. This is also true for traditional taxonomic studies by microscopy with regular adjustments of the classification and taxonomy.
For those reasons (leading to non-homogeneous taxonomies), gap-analyses and comparisons between studies become even more challenging and the curation processes to find potential consensus names are time-consuming. Here, we present a web-based application (Phytool), developed with ShinyApp (Rstudio), that aims to make the harmonisation of taxonomy easier and in a more efficient way, using a complete and up-to-date taxonomy reference database for freshwater microalgae. Phytool allows users to homogenise and update freshwater phytoplankton taxonomical names from sequence files and data tables directly uploaded in the application. It also gathers barcodes from curated references in a user-friendly way in which it is possible to search for specific organisms. All the data provided are downloadable with the possibility to apply filters in order to select only the required taxa and fields (e.g. specific taxonomic ranks). The main goal is to make accessible to a broad range of users the connection between microscopy and molecular biology and taxonomy through different ready-to-use functions. This study estimates that only 25% of species of freshwater phytoplankton in Phytobs are associated with a barcode. We plead for an increased effort to enrich reference databases by coupling taxonomy and molecular methods. Phytool should make this crucial work more efficient.
The application is available at https://caninuzzo.shinyapps.io/phytool_v1/
Multimodal Imaging Characterization of Arteriolosclerotic Plaques in Retinal Vein Occlusion
Authors: Cicinelli Maria Vittoria , Sadiq Saena Arifeen , Mishra Shubhendu , Jampol Lee M. , Mirza Rukhsana G. 
Published: December 2021

BACKGROUND AND OBJECTIVES:
To investigate the multimodal imaging features and the clinical associations of arteriolosclerotic plaques in patients with retinal vein occlusion (RVO).

MATERIALS AND METHODS:
This was a retrospective case series of patients with RVO. Demographic and clinical characteristics were recorded at the time of RVO for each participant. Best-corrected visual acuity and central macular thickness were collected at baseline and observed for 1 year. Arteriolosclerotic plaques were identified on multimodal imaging, and their imaging features were summarized. Differences in demographic and clinical characteristics between eyes with arteriolosclerotic plaques and those with no arteriolosclerotic plaques were reported.

RESULTS:

Seventy-five eyes of 75 patients (39 males; mean age, 72.5 years) were included. Arteriolosclerotic plaques were identified in nine eyes (12%) as segmental, yellow, ill-defined creamy lesions in the arterioles' walls. Baseline macular edema was worse in eyes with arteriolosclerotic plaques than in eyes with no plaques (716.5 μm vs 539.7 μm). Arteriolosclerotic plaques did not interfere with blood flow and regressed in three eyes (33%). Eyes with plaques had worse best-corrected visual acuity (
P
< .001) and lower central macular thickness (
P
= .02) at 12 months than did eyes with RVO and no plaques.

CONCLUSIONS:
Arteriolosclerotic plaques suggest an ischemic or inflammatory involvement of the arteriolar branches in eyes with RVO and are associated with severe macular damage.

[
Ophthalmic Surg Lasers Imaging Retina
. 2021;52:650–657.]
Raça como algoritmo:
Authors: Amrute Sareeta 
Published: December 2021

Conectando o trabalho de software corporativo nos Estados Unidos e na Alemanha, este artigo analisa a racialização de engenheiros de software indianos majoritariamente masculinos por meio do trabalho temporário. Ao fazê-lo, mostro as conexões entre a violência anti-imigrante de hoje e o uso contínuo da raça para sedimentar as divisões do trabalho na indústria como um todo. Para explicar a racialização na indústria tecnológica, desenvolvo um conceito de raça como algoritmo enquanto um dispositivo para demonstrar e explicar como a raça se torna produtiva dentro das economias digitais, a fim de mostrar a flexibilidade da raça enquanto algo que funciona para criar ordens de classificação sensíveis ao contexto. Usando evidências coletadas através da observação em escritórios de tecnologia e por meio de entrevistas com programadores ao longo de cinco anos, percebi que a raça é uma variável essencial, mas continuamente repudiada dentro da construção de economias tecnológicas globais. A investigação se volta para racializações históricas do trabalho temporário e informal nas economias de plantation para iluminar como a informalidade marca trabalhadores cujos direitos podem ser silenciados e permite que as corporações neguem sua culpa em promover a discriminação dentro e fora da indústria da tecnologia, dentro de um campo político que divide “bons” e “maus” migrantes. A partir de evidências etnográficas que os trabalhadores de tecnologia indianos identificam em seus ambientes, este trabalho lê esses sinais como um antídoto para essas negações contínuas.
Palavras-chave: raça; algoritmo; trabalho.
Female forest owners as a market segment? Results from a marketing experiment in the context of a small forest service enterprise
Authors: Lähdesmäki Merja , Matilainen Anne 
Published: December 2021

Broad social changes are reflected in the forest owner structure, which has become increasingly diverse both demographically and in terms of objectives and values. This naturally also impacts forest owners’ interest towards using their forests as well as to their interest in purchasing various forest management services. This development highlights the need for service providers to better segment their clientele and plan their market communication accordingly. However, a surprisingly small amount of research has focused on the impact of marketing arguments for various forest owner segments.
This study provides a first attempt to analyse, through a real-life marketing intervention, how effective marketing arguments are at promoting first thinning to female forest owners. For this, three marketing messages were created and sent out to 300 forest owners in Finland. One message explained the importance of first thinning to provide maximal economic income from forests, one explained the importance of first thinning in relation to biodiversity protection and climate change mitigation, and a control message included no value arguments. The results indicate that contrary to our hypothesis, the marketing message with the economic arguments raised more interest towards the first thinning service among female forest owners than the one with biodiversity protection and climate change mitigation values. The results further show that the control message was found to generate the least interest towards first thinning. This indicates that incorporating value arguments do improve the impact of a marketing message. Key words Market segmentation, female forest owner, marketing argument, economic values, biodiversity values
Presentación
Authors: Stucchi Pierino 
Published: December 2021

Giuristi: Revista de Derecho Corporativo publica su cuarto número, confirmando su vocación como plataforma de difusión del conocimiento académico en el campo jurídico y el compromiso del equipo humano que impulsa cada una de sus ediciones.
Con una vocación internacional, nuestra revista, cuyo comité asesor está compuesto por docentes de cuatro continentes, publica contribuciones de académicos e investigadores de universidades con las cuales la Facultad de Derecho y Ciencias Sociales de ESAN mantiene importantes vínculos de amistad y de cooperación, así como de profesionales que, con enfoque académico, comparten su valiosa experiencia jurídica.
Reflexiones en torno al equilibrio económico financiero
Authors: Nalvarte Salvatierra Pierre 
Published: December 2021

El equilibrio económico financiero es un concepto que, desde un punto de vista matemático financiero, puede ser determinado de manera objetiva, más allá de lo que prescriban las normas legales vigentes.
Es importante ser conscientes de ello. Aun cuando una norma o una cláusula contractual establezcan un mecanismo de restablecimiento del equilibrio económico financiero, puede que este no se alcance en la realidad, pues, para ello, en estricto, se tendría que mantener la rentabilidad esperada o el valor actual neto, de conformidad con el costo del capital aplicable.
El verdadero equilibrio económico financiero sí es tomado en cuenta cuando se evalúa una adenda a un contrato de APP o cuando se estructura una nueva APP. En caso de que se estipule en un futuro contrato un mecanismo que pretenda verdaderamente restablecer el equilibrio económico financiero, este se tendría que materializar elaborando un flujo de caja y observando la TIR o el VAN, incluso cuando esto resulte más complejo.