bluuebunny/crossref_metadata_2025_split huggingface dataset:
EPIDEMIOLOGIA DO VÍRUS MAYARO NA AMÉRICA LATINA ENTRE 2009 A 2019
Authors: Barros Elizabeth Regina de , Pires Rayllany Maylly Turbe , Amorim Murilo Tavares , Holanda Gustavo Moraes 
Published: June 2021

O vírus Mayaro (MAYV), é um arbovírus transmitido pela picada de artrópodes hematófagos, identificado no Brasil em 1955 nas proximidades do rio Guamá, Pará. Entre seus sintomas clínicos destacam-se a febre alta, as artralgias, a cefaleia, a dor ocular e o vômito. A falta de investimentos dos órgãos governamentais, de pesquisas e de vigilâncias epidemiológicas sobre o MAYV, e a habilidade de deslocamento entre espécies, representam os grandes desafios encontrados para se estabelecer a proporção de suas patologias. Neste trabalho, o objetivo foi indicar as características gerais, desafios clínicos, epidemiológicos e evolução viral, que podem resultar em viremias intensas ou alterações imunológicas, através da revisão de literaturas indexadas. Os resultados demostram que fatores ambientais, atividades antrópicas e o crescimento urbano, proporcionaram condições favoráveis para a proliferação do vetor e expansão do vírus pela América Latina, e que os principais países afetados pelo vírus foram Argentina, Bolívia, Brasil, Colômbia, Equador, Guatemala, Haiti, Honduras, México, Panamá, Peru, Uruguai e Venezuela. Em virtude do risco que significa a saúde humana, o vírus MAYV torna-se significativo no que diz respeito a instalações e consolidações de medidas de controle, monitoramento e combate, que possam ser eficazes, para a diminuição de epidemias e endemias na América Latina, assim contribuindo melhor para os serviços de saúde pública.
APRESENTAÇÃO
Authors: FRANÇA Juliana de Sá , SCHRÖDER Luciane Thomé 
Published: June 2021

Prezadas leitoras, prezados leitores! Compreendendo a importância das discussões sobre a prática de estágio curricular pelos cursos de graduação que visam a formar professores, o volume 17, número 41, ano 2021, da Revista Trama apresenta o dossiê Práticas de estágio(s) em discussão. Assim, neste espaço, primou-se pela divulgação de trabalhos que permitem problematizar e (res)significar o papel do estágio supervisionado em cursos de licenciaturas - de modo especial, em Letras -, visto sua obrigatoriedade e a importância que a atividade desempenha enquanto vínculo colaborativo entre a universidade e a escola, portanto, com a sociedade. [...]*TEXTO COMPLETO EM PDF
Bacteriemia por Bacillus cereus y lesiones cerebrales en un adolescente con leucemia linfoide aguda.
Authors: Calderón Gasca Alejandra , Buitrago Escobar Jorge , Luengas Monroy Miguel , Godoy Cordobés Javier 
Published: June 2021

La infección por Bacillus cereus frecuentemente se presenta como una intoxicación alimentaria, no obstante, es una causa rara de bacteriemia, especialmente en pacientes inmunocomprometidos. Se presenta el caso de un paciente adolescente diagnosticado con leucemia linfoide aguda de precursores B, quien durante el curso de una neutropenia febril posterior a la primera fase de quimioterapia, tuvo una bacteriemia por Bacillus cereus, con desarrollo de lesiones cerebrales isquémicas y un desenlace fatal, a pesar del tratamiento antibiótico y del soporte en la unidad de cuidado intensivo. En conclusión, la infección por B. cereus es una causa de infección, especialmente en los pacientes con neutropenia febril, con significativas complicaciones y potencial desenlace fatal. Debe analizarse cuidadosamente su reporte en los hemocultivos, encontrándose frecuentemente en infecciones asociadas a cateteres centrales con perfiles de resistencia al tratamiento con clindamicina y quinolonas, por lo cual el tratamiento empírico con vancomicina es una opción apropiada.
Supervivencia de mujeres jóvenes con cáncer de mama en el Instituto de Cancerología Las Américas entre 2007 y 2016.
Authors: Montoya Restrepo María , Barcenas Carlos , Gómez Wolf Rodolfo , Cock Rada Alicia , Castaño Vasquez Mileny , García García Héctor 
Published: June 2021

Antecedentes: La incidencia de Cáncer de Mama (CaMa) en jóvenes latinoamericanas es 20 %, en Colombia fluctúa entre 10 y 24 %. Su gravedad se atribuye al diagnóstico en estadios avanzados, mayor frecuencia de tumores triple negativo y HER2+. Objetivo: Describir la supervivencia global (SG) de mujeres ≤40 años con CaMa infiltrante operadas en el Instituto de Cancerología Las Américas auna (Medellín-Colombia), entre 2007-2016. Materiales y métodos: Estudio de seguimiento de una cohorte retrospectiva con datos del registro institucional. La supervivencia se calculó desde el diagnóstico hasta la fecha del último control médico o muerte. Se elaboraron curvas de supervivencia de Kaplan Meier y se compararon con log rank test. Resultados. En el periodo se operaron 4.059 mujeres, de estas 390 (9.6 %) tenían ≤40 años, 365 pacientes cumplieron criterios de inclusión. Al diagnóstico 67 (18.3 %) estadio I, 152 (41.6%) estadio II, 140 (38.3%) estadio III y 6 (1.6%) estadio IV. Por subtipos moleculares hubo 87 (24.1 %) Luminal A, 152 (42.1 %) Luminal B HER2-, 72 (19.9 %) Luminal B HER2+, 17 (4.7 %) HER2- enriquecido y 33 (9.1 %) Triple Negativo. 24.4 % de pacientes fueron HER2-positivas. Tuvieron recaída loco-regional 34 (9.3 %) pacientes y 132 (36.2 %) desarrollaron metástasis a distancia. La mediana de seguimiento fue 60 meses (rango 8-142 meses) y la SG de 81.3% (IC95 %: 76.3-85.4). La SG de tumores triple negativo fue la más baja, 67.7% (IC95 %: 48-81.3). Conclusiones. Se encontró mayor porcentaje de pacientes con cáncer Luminal B y HER2 positivo a lo reportado en la literatura. La SG fue similar a las reportadas por otros estudios y menor en estadios avanzados y tumores triple negativo.
Desafios e recomendações para o cuidado intensivo de adultos críticos com doença de coronavírus 2019 (COVID-19)
Authors: Antunes Fernandes Cibelle , Morais da Cunha Aline , Cristine Ritter Contini Hemkemaier Elise , Da Silva do Carmo Karyne , Vitória Pereira Moraes Tamine , Pereira dos Santos Thaís , Fernandes Álvares da Silva Júlia , Eduardo Paiva Bezerra de Melo Luis , Caetano Mateus Natalia 
Published: June 2021

Resumo: A pandemia pela doença de coronavírus 2019 (COVID-19) representa enorme desafio para o sistema de saúde em todo o mundo. Foi nosso objetivo revisar e sintetizar os principais desafios associados ao cuidado intensivo do paciente adulto crítico com COVID-19 e apresentar evidências de recomendações. Trata-se de revisão integrativa de literatura, baseada na experiência de outros países, que tem o potencial de instrumentalizar os profissionais de saúde intensivistas para a prática assistencial ao paciente crítico com COVID-19. Dentre os principais desafios a serem enfrentados pelas equipes de unidades de terapia intensiva (UTI), evidenciados pela literatura, sintetizamos nesse trabalho: a manifestação clínica e diagnóstico para isolamentos rápidos; o manejo da insuficiência respiratória aguda; o papel das terapias medicamentosas reaproveitadas, experimentais e adjuvantes; a prevenção de infecções para pacientes e profissionais; a gestão da mortalidade de pacientes e o gerenciamento da equipe de UTI. O estado atual de conhecimento sobre a COVID-19 é considerado insuficiente e cheio de lacunas, o que configura outro desafio e enseja a necessidade de realização de mais pesquisas clínicas.
Palavras-Chave: COVID-19; Unidade de Terapia Intensiva (UTI); Desafios e Recomendações.
Factor Affecting Farmer Perceptions of the Implementation of Corporate Farming (Case Study at Tani Maju Sejahtera Cooperative, Malang District, East Java Province)
Authors: Dahoklory Matheus , Koestiono Djoko , Toyiba Hery 
Published: June 2021

This research analyzes the factors that influence farmers' perceptions of the implementation of agricultural corporations in advanced prosperous farmer cooperatives of the Malang district. This study uses binary logistic analysis. The determination of the location is done intentionally considering that the progressive, successful farmer cooperative is a cooperative formed by the government, which has become an experimental agricultural corporation in Purworejo Village, Ngantang District, Malang Regency. A simple random sampling technique selected Ninety-two farmers as respondents in this study. The factors analyzed in this study include the farmer's age, education, number of family dependents, land area, land status, and length of farming. The results showed that the education factor had no significant effect on the implementation of Corporate Farming. In contrast, the characteristics of age, number of family dependents, land area, land status, and length of farming had a significant effect on the opportunities for farmers to join Corporate Farming.
Keywords: Farmers, Perceptions, Corporate Farming, Binary Logistic
Penanganan Hukum Terhadap Praktek Prostitusi Melalui Media Elektronik
Authors: Pidada Ida Bagus Anggapurana , Wiratny Ni Ketut 
Published: June 2021

Praktek prostitusi terutama bagi perempuan dan anak sebagai salah satu bentuk tindak kejahatan yang sangat kompleks, tentunya memerlukan upaya penanganan yang bersifat komprehensif dan terpadu. Undang-Undang Informasi dan Transaksi Elektronik (ITE) yaitu UU No. 11 tahun 2008 turut memberikan ancaman pidana atas sebuah tindakan pelacuran online yang dikelola oleh si prostitusi kepada pelanggan-pelangganya. Adapun Pasal 27 ayat (1) UU ITE telah memberikan ancaman pidana namun hanya terbatas pada perbuatan yang mendistribusikan, mentransmisikan, atau membuat dapat diaksesnya informasi elektronik yang melanggar kesusilaan. Metode penulisan yang digunakan yakni metode yuridis normatif dengan pemaparan deskriptif kualitatif dengan menggunakan data primer dan sekunder. Hasil penelitian ini bertujuan untuk memberikan keadilan dam kepastian dalan penegakan hukum terhadap Tindak Pidana. Bagaimana memfungsikan Polri sesuai ketentuan Undang-undang Republik Indonesia Nomor 8 Tahun 1981 Tentang Hukum Acara Pidana (KUHAP) mempunyai kewenangan berdasarkan undang-undang untuk melakukan penyidikan tindak kejahatan. Permasalah prostitusi apabila dilakukan melalui media online ini dapat dikenakan hubungan yang lebih berat karena terjerat oleh yaitu Undang-Undang RI No.11 Tahun 2008 Tentang Informasi dan Transaksi Elektronik, Undang-Undang RI No.44 Tahun 2009 Tentang Pornografi dan KUHP digunakan untuk menjerat para pelakunya.
Hubungan Disiplin Kerja Terhadap Kinerja Karyawan Pada PT. Mensa Bina Sukses Makassar
Authors: Kurnia M Fakhruddin , Adisaputra Tran Fisman 
Published: June 2021

Penelitian ini bertujuan mengetahui tingkat kedisiplinan kerja terhadap peningkatan kinerja pegawai oleh pihak PT. Mensa Bina Sukses Makassar. Metode analisis perhitungan data dilakukan dengan menggunakan metode deskriptif dimana untuk mencari tingkat kedisiplinan karyawan terhadap peningkatan kinerja karyawan serta keterkaitan atau hubungan antara kedisiplinan karyawan terhadap peningkatan kinerja karyawan, serta menggunakan perhitungan analisis kualitatif untuk mencari pengaruh kedisiplinan karyawan terhadap kinerja karyawan. Hasil dari penelitian ini adalah dari hasil menggunakan metode analisis kualitatif didapatkan dari nilai pengaruh yang tinggi sebesar Y = 8,55 + 0,83 X, dimana ada pengaruh antara kedisiplinan dan kinerja karyawan. Dan sebagai masukan bagi perusahaan untuk lebih menegaskan kepada karyawannya dimana kesadaran disiplin kerja sangat berpengaruh terhadap peningkatan kinerja karyawan.
Rancang Bangun Sistem Informasi Pelayanan Surat Keterangan Berbasis Web (Studi Kasus : Desa Dawungan Kecamatan Masaran Kabupaten Sragen)
Authors: Fathoni Wihda  Nashir , Maryam Maryam 
Published: June 2021

Kantor Desa Dawungan merupakan instansi Pemerintahan di Desa Dawungan, Kecamatan Masaran, Kabupaten Sragen. Pembuatan surat keterangan merupakan salah satu pelayanan yang dilakukan Pemerintah Desa Dawungan terhadap masyarakat. Selama ini proses pembuatan surat keterangan masih dilakukan secara manual, masyarakat datang ke Kantor Desa untuk mengurus surat keterangan dan verifikasi oleh petugas. Sering kali masyarakat perlu berulang kali menuju Kantor Desa karena kurangnya beberapa persyaratan. Terbatasnya jam layanan kantor, menjadikan pelayanan ini kurang efektif dan efisien. Tujuan yaitu membangun sistem informasi pelayanan surat keterangan berbasis web. Sistem dikembangkan menggunakan metode waterfall, melalui lima tahapan yaitu Requirement Analysis, Design, Coding, Testing, dan Implementation. Sistem dibangun menggunakan bahasa pemrograman PHP dengan framework Codeigniter dan database MySQL. Hasil pengujian blackbox menyatakan bahwa jalannya fungsi sistem memperoleh hasil valid. Sedangkan pengujian SUS (System Usability Scale) mendapatkan nilai 72,2% yang masuk dalam kategori nilai acceptable. Sistem ini mampu memudahkan petugas kantor desa dalam melakukan pelayanan surat keterangan, meringkas waktu pekerjaan, masyarakat mampu membuat surat keterangan secara mudah dengan input data sesuai kebutuhan dan dapat diakses secara online di website
The Rival Afterlives of George Eliot in Textual and Visual Culture: A Bicentenary Reflection
Authors: O'Neill Helen Anne , Livesey Ruth 
Published: June 2021

Abstract
George Eliot (1819–80) received markedly less national and international acknowledgment during the bicentenary of her birth in 2019 than Charles Dickens did for his bicentenary in 2012. In seeking to understand why, this article conducts a comparative evaluation of Eliot and Dickens in textual and visual media to examine how and where enduring authorial celebrity is constructed. Using Google Books Ngrams, the presence of Dickens and Eliot in textual culture from the 1800s to 2000 is assessed. Eliot is found to keep pace with and/or supersede Dickens in this mass digital repository, a fact that sits at odds with her secondary position in twenty-first-century popular culture. The online catalog of the British Film Institute Reuben Library discloses that adaptations of Eliot's work in film and TV are vastly outnumbered by those of Dickens. We argue that this disparity between Eliot's textual and visual legacies can be traced to extrinsic factors relating to the idea of celebrity and the posthumous management of her reputation, combined with the robust afterlife of nineteenth-century insults about her appearance. At the same time, the intrinsic qualities of her works delimit their easy remediation into mass visual culture. Despite this, our methods of distant reading Eliot's vibrant afterlife in mass textual repositories open up new avenues for exploring her legacy beyond the bicentenary.
Revising the Record: Six Stylized Economic Facts About Pre-Covid US Residential Broadband Markets
Authors: Flamm Kenneth , Varas Pablo 
Published: June 2021

ABSTRACT
This article reviews available public data on the pre-COVID (2014–2018) residential broadband markets in the United States, and presents six data-driven stylized economic facts about these markets. Broadband was a significant household expenditure. There were very limited numbers of competing residential broadband Internet service providers (ISPs) in most local markets. Service prices have not decreased much over time. Quality competition seems quite important. There was very limited entry by new ISPs. Technological innovation in wireless drove much observed new entry.
Formación de estudiantes investigadores en ingenierías: acercamiento a su estado del arte
Authors: Carvajal-Hernández Rosario , Guerrero-Hernández Verónica , Téllez-Vera Erick de Jesús 
Published: June 2021

La actual revisión de la literatura tiene como objetivo identificar la situación actual que presenta la investigación en el entorno de las ingenierías, específicamente en la formación de esta competencia en los estudiantes de educación superior en México abarcando desde el proceso educativo hasta el investigativo, con la finalidad de notificar los avances que se tienen en este país, ya que tales situaciones influyen directamente en el desarrollo de múltiples factores. A través de una revisión documental, se ahondo en los­ métodos y formas en las que se intenta enseñar la competencia de la investigación en los jóvenes universitarios en América Latina, para posteriormente contrastar su realidad con la de México. Lo anterior posibilitó conocer las opiniones y avances que se ha logrado en el ámbito de la investigación, particularmente en el desarrollo de la competencia investigativa en las Instituciones de Educación Superior en la zona de estudio, así como los actores involucrados en esta noble labor de generar y difundir el conocimiento. Finalmente, la enseñanza para saber investigar precisa del desarrollo de capacidades, análisis crítico, deber ético y compromiso con la sociedad que permitan dejar en claro los requerimientos y situaciones adversas que presenta la educación en este momento.
Investigation of different SWCNTs interaction with dopamine and serotonin anticancers: a theoretical study
Authors: Saghayimarouf Nastaran , Monajjemi Majid , Zare Karim , Shamel Ali 
Published: June 2021

Carbon nano tubes (CNTS) have two basic structure as single-walled and multi-walled based on hexagonal plexus of carbon atoms. CNTs can serve as platforms to conjugate other compounds specially in medications purposes by immobilization of biomolecules at their surface. Dopamine and serotonin are two biological molecules which have bifunctional activities as hormone and neurotransmitter. These two molecules have important roles as neurotransmitters in the central and peripheral nervous systems but serotonin functions as a mood regulator, while dopamine is connected to the “pleasure center”. In this article we optimized molecular and structural properties of connected dopamine and serotonin with SWNTS with four different diameters (7.0,7.5,7.7 and 10.0 nm) by using molecular quantum methods such as NMR shielding tensor data by B3LYP level of theory with 6-31 G(d) as a basis set, mk and frequency methods. Theoretical computations were performed to study NMR chemical shift data including magnetic shielding tensor (σ, ppm), shielding asymmetry (η), magnetic shielding anisotropy (σaniso), magnetic shielding isotropy (σiso) , skew of a tensor (Κ) and chemical shift anisotropy (Δσ) and span (Ω) at various rotation angles around a specific rotation , physical and chemical properties of atomic nuclei , frequency data by B3LYP/6-31g level of theory and POP method using gaussian 09 program.
Investigation of Complex Structural Designing of Mobile Facilities for Shipbuilding in Lithuanian Sea Region
Authors: ASTRAUSKAS Tadas , SAMOFALOV Michail 
Published: June 2021

In the paper, it is proposed to cover by a mobile moving facility the shipyard open site, in Klaipeda, Lithuania (the EU). The facility of 40 m span consists of transversal frames, which are arranged by the step of 6.0 m, and a system of braces. Two types of steel frames have been considered: trussed and continuous. The actions are specified according to the design codes (Eurocode 3) and climatological data. In dynamic analysis, the longitudinal direction is defined for an inertia action, simulating braking. For calculating, a special algorithm of three stages has been prepared. At the first stage, three calculation schemes of one transversal frame were created. For the proposed schemes of the mobile moving facility, the calculation of only a transversal frame is effective in the preliminary determination of the cross-sectional areas and of the total structural weight. At the second stage, the frames were joined by braces. A preliminary comparison of the calculation results of the models was carried out after the first and second stages of the analysis. At the third stage, the dynamic analysis was performed and the influence of the dynamic impact was estimated. Finally, we compared the calculation results of three different FEM models and chose the most appropriate one. To sum up the investigations, conclusions and recommendations are presented.
Preclinical Appraisal of Hematinic Potential of Mandura Bhasma for Treating Anemia
Authors: Khobragade Deepak S. , Potbhare Mrunali S. , Pimpale Awdhut , Wankhede Sagar B. , Tempe Chandrashekhar R. 
Published: June 2021

Aims: To evaluate hematinic potential of mandura bhasma.
Study Design: Experimental study.
Place and Duration of Study: Institute of Pharmaceutical Education and Research, Wardha, Maharashtra, India. 6 Months.
Methodology: The anti-anaemic potential of Mandura bhasma in Wistar rats was investigated. Anaemia was induced in rats with phenyl hydrazine hydrochloride at a dose of 10 mg kg-1 body weight by oral administration. Anaemia was treated with mandura bhasma administered in three different doses based on body weight.
Results: In vivo investigation showed that though the dose of 6mg kg-1 body weight of mandura bhasm produced only a minimal antianaemic (hematinic) effect, oral daily dose of 11 mg kg-1 body weight and 22mg kg-1 body weight a produced a significant (P < 0.05) antianaemic effect when compared to standard drug ferrous sulphate indicating dose dependent activity.
Conclusions: The results indicate that Mandura Bhasm have very potential dose dependant hematinic activity and can be a safe and effective drug for treating anemia.
Impact of errors in spot size and spot position in robustly optimized pencil beam scanning proton‐based stereotactic body radiation therapy (SBRT) lung plans
Authors: Rana Suresh , Rosenfeld Anatoly B. 
Published: June 2021

AbstractPurposeThe purpose of the current study was threefold: (a) investigate the impact of the variations (errors) in spot sizes in robustly optimized pencil beam scanning (PBS) proton‐based stereotactic body radiation therapy (SBRT) lung plans, (b) evaluate the impact of spot sizes and position errors simultaneously, and (c) assess the overall effect of spot size and position errors occurring simultaneously in conjunction with either setup or range errors.MethodsIn this retrospective study, computed tomography (CT) data set of five lung patients was selected. Treatment plans were regenerated for a total dose of 5000 cGy(RBE) in 5 fractions using a single‐field optimization (SFO) technique. Monte Carlo was used for the plan optimization and final dose calculations. Nominal plans were normalized such that 99% of the clinical target volume (CTV) received the prescription dose. The analysis was divided into three groups. Group 1: The increasing and decreasing spot sizes were evaluated for ±10%, ±15%, and ±20% errors. Group 2: Errors in spot size and spot positions were evaluated simultaneously (spot size: ±10%; spot position: ±1 and ±2 mm). Group 3: Simulated plans from Group 2 were evaluated for the setup (±5 mm) and range (±3.5%) errors.ResultsGroup 1: For the spot size errors of ±10%, the average reduction in D99% for −10% and +10% errors was 0.7% and 1.1%, respectively. For −15% and +15% spot size errors, the average reduction in D99% was 1.4% and 1.9%, respectively. The average reduction in D99% was 2.1% for −20% error and 2.8% for +20% error. The hot spot evaluation showed that, for the same magnitude of error, the decreasing spot sizes resulted in a positive difference (hotter plan) when compared with the increasing spot sizes. Group 2: For a 10% increase in spot size in conjunction with a −1 mm (+1 mm) shift in spot position, the average reduction in D99% was 1.5% (1.8%). For a 10% decrease in spot size in conjunction with a −1 mm (+1 mm) shift in spot position, the reduction in D99% was 0.8% (0.9%). For the spot size errors of ±10% and spot position errors of ±2 mm, the average reduction in D99% was 2.4%. Group 3: Based on the results from 160 plans (4 plans for spot size [±10%] and position [±1 mm] errors × 8 scenarios × 5 patients), the average D99% was 4748 cGy(RBE) with the average reduction of 5.0%. The isocentric shift in the superior–inferior direction yielded the least homogenous dose distributions inside the target volume.ConclusionThe increasing spot sizes resulted in decreased target coverage and dose homogeneity. Similarly, the decreasing spot sizes led to a loss of target coverage, overdosage, and degradation of dose homogeneity. The addition of spot size and position errors to plan robustness parameters (setup and range uncertainties) increased the target coverage loss and decreased the dose homogeneity.