bluuebunny/crossref_metadata_2025_split huggingface dataset:
Why Orthopaedic Residents Must Be Exposed to and Taught Value-Based Care
Authors: Murrey Daniel B. , Bosco Joseph A. , Jevsevar David S. , Koenig Karl 
Published: March 2021

Abstract:
The shift to value-based care is changing the practice of medicine. In order to prepare our orthopaedic trainees to survive in a value-based health-care environment, we must expose them to and educate them about value-based programs. This creates both challenges and opportunities for training programs. Academic medical centers (AMCs) will need to carefully consider how to adopt value-based programs and agreements, and assess whether they need alternative facilities, partnerships, or processes in order to be successful. Process improvement principles to adapt physician behavior, the introduction of outcome metrics into the surgical decision-making process, and the development of team-based care can greatly enhance the likelihood of success. AMCs should embrace these challenges to ensure that their residents are well-prepared for the future.
Geological Implications for Gas Saturation of Bottom Sediments in Sedimentary Basins in the Southeastern Sector of the East Siberian Sea
Authors: Gresov A.I. , Yatsuk A.V. 
Published: March 2021

Abstract
—We present research results for the geologic structure of the De Long, Aion, and Pegtymel sedimentary basins of the East Siberian Sea. The materials of geological surveys and drilling in their land area and island surroundings, the data obtained from geophysical surveys conducted by Dal’morneftegeofizika, MAGE, and Sevmorgeologiya, and the seismic and deep-drilling data on the U.S. sector of the Chukchi Sea are summarized and analyzed. Pre-Paleozoic strata and the sedimentary cover have been identified throughout the sections of the sedimentary basins, which suggests the existence of a geologic “cover–basement” boundary rather than an arbitrary called “acoustic basement” horizon. The data on the geologic structure and gas saturation of the upper parts of the sedimentary sections were obtained during the study and gas-geochemical testing of core samples and bottom sediments from coastal shallow wells and corers. Gas contained in the rocks and bottom sediments in the study area includes hydrocarbon gases (HCGs) (СН4, С2–С5, and their unsaturated homologues), СО2, Н2, Не, N2, Ar, and, seldom, CO and H2S. The data on gas saturation of bottom sediments and the geochemical parameters of their syngenetic and epigenetic gases are presented. Areas of abnormal saturation of sediments with CO2, СН4, other HCGs, H2, and He (&gt;5, 0.05, 0.001, 0.005, and 0.005 cm3/kg, respectively) have been identified, and maps of the gas saturation patterns in bottom sediments have been compiled. It is established that both gas saturation and distribution are determined mainly by the geologic evolution, tectonics, magmatism, geocryologic conditions, lithologic composition, catagenesis, coal content, bituminosity of sedimentary rocks, and oil and gas potential of the study area.
An Awakening Magmatic System beneath the Udina Volcanic Complex (Kamchatka): Evidence from Seismic Unrest of 2017–2019
Authors: Kugaenko Yu.A. , Saltykov V.A. , Koulakov I.Yu. , Pavlov V.M. , Voropaev P.V. , Abkadyrov I.F. , Komzeleva V.P. 
Published: March 2021

Abstract
—The Udina volcanic complex located in the southeastern part of the Klyuchevskoy group of volcanoes in Kamchatka remained dormant for several thousand years, but the magmatic system beneath the area may be awakening judging by seismic unrest. Seismicity in the area is characterized by data from permanent regional seismic stations and campaign local stations, as well as by data of the Kamchatka earthquake catalog. Seismic activity having nucleated at shallow depths in the vicinities of the Udina volcanoes since October 2017 may reflect a beginning cycle of volcanism. The earthquakes are mainly long-period (LP) 0.5–5 Hz events, which are commonly attributed to the movement of viscous magma and resonance phenomena in magma conduits. Such earthquakes may be a response to inputs of new magma batches to the plumbing system that feeds the volcanoes and thus may be precursors of volcanic unrest. Seismic campaigns of May–July 2018 near the Udina complex provided more rigorous constraints on earthquake coordinates and origin depths and showed that most of the earthquakes originated within 5 km beneath the Bolshaya Udina Volcano. Seismic tomographic inversion using the LOTOS code revealed a zone of high P-wave velocities, low S-wave velocities, and a high vP/vS ratio directly beneath the volcano. Such a combination of parameters typically occurs in active volcanic areas and marks intrusion of partially molten magma and/or liquid fluids. The velocity anomaly detected in 2018 is shallower than that recovered in 2014–2015. The seismic evidence, along with the available geological and geophysical data, record the movement of viscous magma related to the Udina feeding system in the middle crust, which is implicit proof for connection between the intermediate crustal and deep mantle magma sources renewed after a long lull.
Causes of the Occurrence of A-Type Volcanic Rocks in Active Continental Margins (Southern Sikhote-Alin, Russian Far East)
Authors: Grebennikov A.V. , Maksimov S.O. 
Published: March 2021

Abstract
––New isotope-geochemical data on the volcanic complexes of the South Yakut and Martel volcanic depressions in southern Primorye are presented. Their formation in the early Eocene (54.3 Ma) and Late Cretaceous (83.5 Ma), respectively, is evidenced by U–Pb zircon dating (LA-ICP-MS). Based on the geochemical characteristics, it is concluded that the volcanics are typical A-type igneous rocks. Their formation coincides with the sudden change in the vector of motion of the Pacific slab with respect to the continent in the Campanian and Paleocene–Eocene, which caused destruction of the slab with its probable discontinuity and the injection of the subslab asthenosphere. The effect of mantle fluids on the continental lithospheric-rock melting determined the generation of magmas with the specific geochemical features of A-type igneous rocks. The regularities of their composition are due to the deep-seated reduced F-rich fluids that caused the intense differentiation of magmas accumulating fluidized melts enriched in mobile components in the apical part.
Data-Driven Integration to Delineate Zonal Isolation and Casing Deterioration Using Advanced Ultrasonic Technology – A Blueprint to Well Integrity Evaluation
Authors: Khan Mohammad Rasheed , Ahmed Hassaan , Bari Abdul , Rashid Kamran , Ali Syed Dost , Zubair Talha , Anjum Usman 
Published: March 2021

Abstract
State-of-the-art advanced ultrasonic measurement through the Leaky-Lamb wave imaging technique (more commonly known as the flexural waveform analysis) was introduced nearly two decades ago to expand the envelope beyond which the classical pulse-echo evaluation operated. This technology has proven to be a game-changer in cement evaluation through provision of an integrated analysis which deconvolutes beyond the casing-cement interface and investigates further into the third interface. In this work, we integrate the cutting-edge analysis provided by ultrasonic flexural mode with the classical pulse-echo approach to yield a novel well-integrity evaluation blueprint. Subsequently, it is shown how this workflow is applied to an ultra-high pressure (UHP) exploratory well for integrity evaluation which will aid in future optimization of completion strategies and constitute a continuous improvement cycle for other wells. The subject well faced potential integrity related uncertainties due to fishing and cementing related issues.
A three-tier approach was adopted to develop the blueprint, starting off with problem identification with respect to the various operations and incidents that occurred on this well. Next, based on the anticipated problems, associated solutions to evaluate the same were investigated by considering the technologies and standard procedures practiced by the industry. Finally, based on the previous two steps, a multi-physics approach was adopted that makes use of a combination of pulse-echo and flexural ultrasonic analysis, in addition to multiple well integrity workflows. Consequently, combination of flexural attenuation and acoustic impedance allows for a comprehensive evaluation of the medium behind the casing through the Solid-Liquid-Gas map. Simultaneously, it is possible to quantify casing thickness and internal radius variations through pulse-echo amplitude and resonance frequency characterization. Furthermore, the Third-Interface-Echo analysis is conducted to determine annulus geometry descriptions and produce a unique in-situ casing centralization measurement.
The proposed well integrity blueprint contains various building blocks that are key to evaluation processes and provide a linkage-based approach to delineate potential problems. Accordingly, application of this blueprint illustrated the investigative approach it delivers with respect to cement barrier classification and casing condition assessment
Challenging Catenary Coiled Tubing Thru Tubing Screen Deployment Operation Offshore Borneo
Authors: Jong Seng Wei , Yong Yee Tzen , Azizan Yusri , Hampson Richard , Hj Abd Rani Rudzaifi Adizamri , Muhammad Khairul Amilin , Gurmin Ian 
Published: March 2021

Abstract
Production decline caused by sand ingress was observed on 2 offshore oil wells in Brunei waters. Both wells were completed with a sub-horizontal openhole gravel pack and were subsequently shut in as the produced sand would likely cause damage to the surface facilities.
In an offshore environment with limited workspace, crane capacity and wells with low reservoir pressures, it was decided to intervene the wells using a catenary coiled tubing (CT) vessel. The intervention required was to clean out the sand build up in the wells and install thru-tubing (TT) sand screens along the entire gravel packed screen section.
Nitrified clean out was necessary due to low reservoir pressures while using a specialized jetting nozzle to optimize turbulence and lift along the deviated section. In addition, a knockout pot was utilized to filter and accommodate the large quantity of sand returned.
The long sections of screens required could not be accommodated inside the PCE stack resulting in the need for the operation to be conducted as an open hole deployment using nippleless plug and fluid weight as well control barrier. A portable modular crane was also installed to assist the deployment of long screen sections prior to RIH with CT.
Further challenges that needed to be addressed were the emergency measures. As the operation was to be conducted using the catenary system, the requirement for an emergency disconnect between the vessel and platform during the long cleanout operations and open hole deployment needed to be considered as a necessary contingency. Additional shear seal BOPs, and emergency deployment bars were also prepared to ensure that the operation could be conducted safely and successfully.
Advance Live-Well Deployment System in Caspian Sea Wells
Authors: McClean C. , Parra D. , Piven A. , Rhahimov K. , Hadiaman F. 
Published: March 2021

Abstract
Over the past years the usage of coiled tubing as a prefer method to deploy long and heavy guns in highly deviated wells has been widely spread in the oil industry to provide a single run without killing the well, perforate in underbalance conditions, reduce risks and improve job efficiency. The three wells are located in the Caspian Sea. In two wells, the objective was to isolate lower intervals and perforate a new zone through tubing and casing between two packers. On the other well, the objective was to perforate a new interval through casing after running a new completion and isolate lower production zones.
Due to the challenges involving gross length of the new intervals, guns size, well deviation and live deployment needs several techniques were evaluated. The best approach was to use an Advance Live-Well Deployment (ALWD) system to deploy and retrieve the guns with a tube wire-enabled Coiled Tubing Telemetry (CTT) system focus on both safety and cost saving compare with conventional wireline perforating. Extensive job planning involved coiled tubing (CT) simulations to reach target depths, shock loading modeling to ensure forces are within CT string limitations, system integration test to verify deployment/reverse technique procedure and system communication to electrically activate guns.
CTT integrated sensor assembly was used during deployment/reverse operation with a tension, compression and torque (TCT) sub-assembly to monitor accurate upward/downward forces. In addition, CTT logging adapter assembly was used for depth correlation and electrical guns activation. The ALWD system; composed by connectors and deployment blow out preventor (BOP), prove to be an efficient way to run, perforate and retrieve gross intervals of 212 m, 246 m and 104 m with guns successfully. During all these jobs several lessons learnt were created in order to improve the deployment/reverse procedure for future jobs including not only operational steps but also deployment/reverse bottom-hole assembly (BHA) configurations.
Based on the success of these case histories, the ALWD combined with CTT system has been proven to be the preferred method when dealing with long perforation intervals in life well conditions, thru-tubing environment.
Case Study of Underbalance Coiled Tubing Drilling to Increase Well Productivity and Ultimate Recovery in Tight Gas Reservoir Onshore Field, Abu Dhabi
Authors: Ladmia Abdelhak , Culen Martin , Al Katheeri Abdulla Bakheet , Al Hosani Fahad Mustfa Ahmed , Edmonstone Graham F. J. , Mantilla Alfonso , Baslaib Mohamed Ahmed , Nabil Ihab Mohamed , Yousfi Fawad Zain , Al Hosani Mariam Ahmed , Almenhali Salem Saleh , El Shahat Ayman , Abdulsallam Fouad , Al-Khatib Haitham Mohamed , Al Jaberi Fawzi Omar , Al Beshr Huda , Mcneilly Kevin Dean 
Published: March 2021

Abstract
Coiled Tubing Drilling (CTD) has been growing and developed rapidly through the last two decades. There have been numerous highly successful applications of CTD technology in Alaska, Canada, Oman and the United Arab Emirates (Sharjah Sajaa and Dubai Murgham fields), among other places. Currently, Saudi Arabia has undertaken a campaign for the last seven years that has shown successful results in gas reservoirs.
ADNOC initiated a trial Coiled Tubing Underbalanced Drilling (CTUBD) project in the onshore tight gas reservoirs in Abu Dhabi, United Arab Emirates beginning operations 1-December-2019. The initial trial will consist of three (3) wells. The purpose of the trial is to assess the suitability of CTUBD for drilling the reservoir sections of wells in these fields, and further application in others.
The reason for choosing coiled tubing for drilling the reservoir sections is based upon the high H2S content of the reservoir fluids and the premise that HSE can be enhanced by using a closed drilling system rather than an open conventional system.
The three wells will be newly drilled, cased and cemented down to top reservoir by a conventional rig. The rig will run the completion and Christmas tree before moving off and allowing the coiled tubing rig to move onto the well. The coiled tubing BOPs will be rigged up on top of the Christmas tree and a drilling BHA will be deployed through the completion to drill the reservoir lateral.
The wells will be drilled underbalanced to aid reservoir performance and to allow hole cleaning with returns being taken up the coiled tubing / tubing annulus. The returns will be routed to a closed separation system with produced gas and condensate being primarily exported to the field plant via the production line, solids sparge to a closed tank or pit and the drilling fluid re-circulated. The primary drilling fluid will be treated water; however, nitrogen may be required for drilling future wells in the field and will be required regardless for purging gas from the surface equipment during operations. A flare will also be required for emergency use and for start-up of drilling. If the trial proves a success, a continuous drilling plan will be put in place.
Intervention Multi-Skilled Crew Reduces Personnel on Board, Footprint and Costs
Authors: Hillier Jill , Bruce Wayne , Arnold James , Delot Marc 
Published: March 2021

Abstract
This paper will highlight the advantages of multi-skilling intervention personnel on offshore installations. Crew members are from different service lines including Wireline, Slickline, Coiled Tubing and Gas Lift (completions). It will discuss how a multi-skilled crew is formed, specific scenarios on how they are utilized and how to develop and maintain the competencies of these personnel.
Through Multi-skilling personnel there is a potential to reduce crew sizes up to 50% for some standard intervention operations. Multi-skilling personnel during the 2020/2021 global pandemic has become critical as personnel movements across regions have become limited or nonexistent in some cases.
Reducing personnel on board has several benefits including lower personnel and logistics costs, lower carbon footprint of transportation of personnel, higher utilization of personnel, and motivating and retaining high skilled personnel as they learn new skills. It also allows for local personnel to be used for multiple operations permitting lower cost interventions to continue during a major global crisis.
Implementing Business Analytics Software to Optimize Coiled Tubing Operations: A Digital Approach to Operations Efficiency
Authors: Bautista Alarcon Xaymaca , Torres Carlos 
Published: March 2021

Abstract
This paper describes how business analytics novel software tools combined with advanced data management techniques can be integrated to management workflows and decision-making processes of a Coiled Tubing Service Company (CTSC).
An advanced data wrangling process (transforming and mapping data) was designed and implemented to unify current and historical coiled tubing operational data into a single data set. The latter was regularly updated with the latest operational information through an automated data querying process that eliminated the need for manually repeating the data wrangling. A Business Analytics Software (BAS) was used to accelerate the engineering of a Data Analytics (DA) process, identify correlations and trends, design data models, and create relevant Key Performance Indicators (KPI). Finally, BAS visualization tools were used to prepare and publish comprehensive cloud-based Business Intelligence (BI) dashboards and reports.
The BI dashboard allows the coiled tubing company to quickly perform accurate and efficient analysis of the KPI trends of its coiled tubing units and well interventions. The cloud-based Dashboard enables the CTSC to:
Effectively identify Coiled Tubing Strings utilization, costs, failures, vendors, and design performance trends based on factual data, thus enabling informed pipe management decisions. Clearly Identify high performance coiled tubing units and crews and make strategic decisions for high profile jobs. Identify equipment failures, non-productive time (NPT) trends and define, implement, and monitor maintenance and asset management strategies to tackle the failures with mayor impact on operations performance. Easily incorporate fresh operational data and detect record-breaking operations. Improve Customer Relationship Management by a quickly responding to customer inquiries for tailor-made operations performance reports. Decrease workload on repetitive processes by enabling reports generation with relevant and accurate data faster that previous methods in place. Quickly customize and create accurate documentation compiling relevant performance data in a consistent and standardized fashion. Perform well interventions technical analysis.
The contemporary approach to integrate BI Software to coiled tubing operations is a step change in how service companies and operators are analyzing and monitoring performance (efficiency, safety, and quality) to differentiate from each other, optimize results and minimize costs. This paper describes an example of a simple yet sophisticated and effective way of incorporating digital tools in the oilfield services processes by utilizing in house talent and resources.
Quercetin: A Potential Candidate for the Treatment of Arthritis
Authors: Goyal Ahsas , Agrawal Neetu 
Published: March 2021

:
Diet plays a significant role in ensuring healthy life and the bioactive compounds present in food and medicinal plants may be developed as drugs that combat various illnesses. A bioactive flavanoid, quercetin which is a dietary component possesses numerous health-promoting effects. In preclinical models of rheumatoid arthritis, gouty arthritis and osteoarthritis, quercetin has shown significant joint protective effects. Taking into account the significance of this compound, the present review discusses its anti-arthritic properties, demonstrating its mechanism of action for the treatment of arthritis with its therapeutic potential.
Large-scale Prediction of Drug-Protein Interactions Based on Network
Information
Authors: Li Xinsheng , Ma Daichuan , Ren Yan , Luo Jiesi , Li Yizhou 
Published: March 2021

Background:
The prediction of drug-protein interaction (DPI) plays an important role in drug
discovery and repositioning. Unfortunately, traditional experimental validation of DPIs is expensive and
time-consuming. Therefore, it is necessary to develop in silico methods for the identification of potential
DPIs.

Method:
In this work, the identification of DPIs was performed by the generated recommendation of the
unexplored interaction of the drug-protein bipartite graph. Three kinds of recommenders were proposed to
predict the potential DPIs.

Results:
The simulation results showed that the proposed models obtained good performance in crossvalidation
and independent test.

Conclusion:
Our recommendation strategy based on collaborative filtering can effectively improve the
DPI identification performance, especially for certain DPIs lacking chemical structure similarity or genomic
sequence similarity.