bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proximal Üreter Taşlarının Tedavisinde Uygulanılan İki Farklı Litotripsi Tekniğinin Karşılaştırılması
Authors: ARAZ Şeyhmuz , ASLAN Rahmi , SEVİM Mehmet , TAKEN Kerem 
Published: December 2021

Amaç: Proximal üreter taşı olan hastalarda Üreteroskopik lazer litotripsi (LL) ve pnömotik litotripsi (PL) tedavi yöntemlerinin etkinliklerinin ve güvenirliğinin araştırılması amaçlandı.
Gereç ve yöntem: 1 ekim 2013 ile 1 ekim 2018 tarihleri arasında kliniğimizde proximal üreter taşı nedeniyle Üreteroskopik LL veya PL tedavisi uygulanan 244(LL:139, PL:105) hastanın dosyaları retrospektif olarak incelendi. Sonuçlar, tedaviden 1 gün ve 1 ay sonra direkt üriner sistem grafisi, üriner ultrasonografi, kontrastsız bilgisayarlı tomografi veya intravenöz ürografi görüntülemeleri ile değerlendirildi. Üreteroskopik LL ve PL tedavi yöntemlerinin ameliyat süreleri, hastanede yatış süreleri, taşsızlık oranları ve komplikasyon oranları karşılaştırıldı.
Bulgular: Bu çalışmaya LL grubuna 139(%56.9), PL grubuna 105(%43.1) hasta olmak üzere toplam 244 hasta dahil edildi. LL grubunda 101 (%72.6) erkek, 38 (%27.42) bayan hasta, PL grubunda ise 79 (%75.2) erkek, 26 (%24.8) bayan hasta mevcuttu. LL grubuna alınan hastaların yaş ortalaması 44.47 ±15.702 yıl, PL grubuna alınan hastaların yaş ortalaması ise 41.24±13.723 yıl olarak saptandı. LL grubunda taş boyutları ortalaması 11.26±3,752 mm, PL grubunda ise 10.98± 4,572 mm olarak saptandı. LL grubunda taşların taraf dağılımı sağ %57.6, sol %42.4; PL grubunda ise sağ %43.8, sol %56.2 olarak saptandı. Majör Komplikasyon oranları sırasıyla %6.4 ve %9.4 olarak tespit edildi(P>0,05). Postoperatif 1. Ay Taşsızlık oranları LL grubunda %87.1, PL grubunda ise %81 olarak izlendi(P>0,05). Postoperatif hastanede yatış süreleri LL grubu 17.12±4,511 saat, PL grubunda ise 25.26±29,657 saat olarak tespit edildi(P
Strategi Meningkatkan Daya Saing dan Upaya Bertahan Saat Pandemi Covid 19 Pada Usaha Kecil dan Menengah PT Sasak Maiq Batu Layar Lombok Barat
Authors: Artika Ida Bagus Eka , Irianto Irianto , Marini Ida Ayu Ketut , Helmida Baiq Ertin 
Published: December 2021

The sustainability of PT Sasak Maiq, in West Lombok Regency, as one of the Small and Medium Enterprises has recently been threatened by the Covid - 19 pandemic which began to hit Indonesia in early 2020. PT Sasak Maiq is concerned about this because it has an impact on reducing turnover sales of their products. This requires a strategic study, to be able to maintain the existence of PT Sasak Maiq in the Covid-19 pandemic, which cannot be predicted when it will end. This research is a descriptive study with the aim of knowing which strategies are suitable to be applied in order to maintain the existence of PT Sasak Maiq in the future. The data is sourced from stakeholders, with an analysis technique in the form of environmental analysis (SWOT Analysis). The results showed that the suitable strategy to be applied to maintain the sustainability of PT Sasak Maiq is the ST strategy, which is in the form of a diversification strategy, by creating the new unique product, strengthening the online marketing network, maintaining a price strategy, maintaining relationships with marketing networks both at domestic and abroad, so that it can maintain demand for its products.
Analysis of Antenatal Care Visit at the Work Area of Kilasah Health Centre Serang City in 2019
Authors: Novelia Shinta , Rukmaini  , Tohir Mulliawati 
Published: December 2021

Background: Maternal mortality rate (MMR) in Indonesia was 359/100,000 live births, while in Banten Province it reaches 264 cases. The high rate of maternal and infant mortality is partly due to the frequency of irregular pregnancy check-ups. This is a problem because not all pregnant women check their pregnancy regularly so that abnormalities that arise in pregnancy cannot be detected as early as possible.
Objective: This study aimed to analyze factors related to antenatal care (ANC) visits in the Kilasah Health Center Work Area Serang City in 2019.
Methodology: The research method used was correlation research with a cross sectional study approach. The research sample was 91 midwives in the Work Area of ​​the Kilasah Health Center, Serang City.
Results: From the results of the study, it was known that factors related to ANC visits in the Kilasah Health Center Work Area include knowledge (p = 0.023), education (p = 0.000), and family support (p = 0.004).
Conclusions and Suggestions:. It is hoped that the the Health Centre more intensive in providing health education, so that public health knowledge will increase and there will be changes in public health behavior towards the better.
Overview of Nurses Perception about Caring Based on Technology in the ICU and ER of Jember Region Hospital
Authors: Rohmawati Nur , Ardiana Anisah , Rosyidi Muhammad Nur Kholid 
Published: December 2021

Caring in acute and critical care rooms has a more complex and dynamic nature due to unstable patient conditions and requires more attention from nurses. Nurses' technological competence represents their caring based on nursing science practice. This study aimed to find out how nurses’perception of caring based on technology in the Intensive Care Unit and Emergency Room in Jember Region. This study used a quantitative method based on a descriptive survey. This study used a total sampling, with a total of 47 nurses as respondents. The researcher used a demographic questionnaire and modification of caring attribute, professional self-concept, and technological influence scale to collect data. In this study, univariate analysis was applied to analyze the data. The median score was 68, as the scores approach the maximum score of 76. This study demonstrates that nurses have a good perception toward caring based on technology. The conclusion on this study is nurses perception of caring based on technology are generally positive. To further improve nurses' perceptions of caring expressed through technological competence, the researcher advises the managerial department to facilitate education and training on technological competence in order to provide better care and caring to patients.
Keywords: Caring Based on Technology; Nurses; Perception
INCOME ANALYSIS OF VEGETABLE TRADERS IN AIKMEL TRADITIONAL MARKET AIKMEL SUB DISTRICT EAST LOMBOK REGENCY
Authors: Amin Muhammad 
Published: December 2021

Market is a place for public facilities to complete the needs of the community and is a center for community commerce. Not only that, the market continues to play a role for price stability, where market value is one of the benchmarks for assessing inflation.
The purpose of this study was to determine the income of vegetable traders in Aikmel Traditional Market, Aikmel District, East Lombok Regency and to find out the obstacles faced by vegetable traders in running their business at Aikmel Traditional Market, Aikmel District. The determination of the research area was carried out by purposive sampling, namely based on certain considerations in accordance with the research objectives. Considerations for choosing the Aikmel Traditional Market where the research was conducted, because the Aikmel Market is classified as the type of vegetables that are sold, it is very complete and the traders there pick them up quite close to the source of the farmers, besides that the Aikmel market provides comfort and peace when transacting. The sampling method is by using the census method.
Climate changes and trends over India
Authors: THAPLIYAL V. , KULSHRESTHA S.M. 
Published: December 2021

Based on the instrumental observations of over a century available in India, attempt is made
to study if there is a clear-cut evidence of any climate change or trend over .India with particular reference to
rainfall, surface temperature, atmospheric pressure and total ozone. The study concludes that while there are year to year random. fluctuations in these atmospheric variables and there are certain epochal increases and decreases in respect of rainfall and .surface temperature, .there appears to be no systematic climate charge or trend over India. There IS also no evidence of ozone depletion over India.
Estimation of soil temperature by Harmonic analysis
Authors: KULSHRESTHA MANJUSHA , SHEKH A. M. 
Published: December 2021

Soil temperatures recorded at 5.10 and 20 cm depth at Anand station of Gujarat state for the period of 1982-93 were analyzed by harmonic analysis and tested it for the year 1998. The amplitude of the soil temperature wave for the various depths decreases from a maximum of 5.76° C in the first harmonic to 0.96°C in the third harmonic. First, second and third harmonic explained 55 to 76 percent, 18 to 37 percent and 2 to 4 percent of the total variance, respectively. Total percentage of total variance covered by the three harmonics at different depths are in the range of 95 to 97 percentage for the period of 1982-93 normalized data series which shows the applicability of harmonic analysis in describing soil temperatures.

The weekly observed and computed soil temperatures by harmonic analysis were in agreement and their differences were non significant by Chi-Square test.
Integrated control system of segetal vegetation in winter wheat crops in Forest-Steppe conditions
Authors: Ptashnik M.M. , Zaiats P.S. , Dudnyk S.V. , Brukhal F.J. , Oksimets O.L. 
Published: December 2021

As a result of many years of research in a stationary field experiment conducted in the conditions of the northern forest-steppe on Gray forest large-sawn light loamy soil, the regularities of the influence of methods of its main cultivation, doses and terms of herbicide application on the level of contamination of crops with segetal vegetation and the competitiveness of winter wheat in short-term crop rotation were established.It was found that the competitive pressure of weeds on winter wheat both for plowing and flat–cutting loosening to a depth of 20–22 cm was minimal and amounted to 6.9–13.2%, and the crop pressure on weed cenosis was noted in the range of 81.5–84.8%. The use of a herbicide based on D. R. prosulfuron (750 g/kg) increased this indicator to 90%.With flat-cutting loosening, the potential contamination of the upper 0–5-centimeter layer of soil, from which the bulk of weeds germinate, in the crops of the studied crop was 31.3–31.8% higher compared to plowing. Indicators of potential contamination and the rate of germination of weed seeds with this method of basic tillage caused a high level of actual weediness of winter wheat crops in a short-term crop rotation. However, systematic tillage without layer turnover ensured gradual self-cleaning of the lower part of the arable soil layer from weed seeds.The highest yield of winter wheat 6.11 t/ha of grain was obtained during plowing and the autumn period of application of the herbicide based on D. R. prosulfuron (750 g/kg) at a rate of 20 g/ha in the development phase of the BBCH 11–13. The use of the herbicide in autumn compared to spring periods provided an increase in the grain yield by 0.24–0.54 t/ha for plowing and by 0.48–0.64 t/ha for non – polar cultivation.Economically, the most appropriate technology for controlling segetal vegetation in winter wheat crops is recognized, which provides for plowing to a depth of 20–22 cm as the main tillage with the introduction of N80P60K80 and earning by-products of its predecessors into the soil. To increase the effectiveness of crop contamination control in the integrated plant protection system, it is also proposed to use autumn application of a herbicide based on D. R. prosulfuron (750 g/kg) at a dose of 20 g/ha in the phase of 2–3 leaves in the culture.
A Study on English Collocation Errors of Thai EFL Students
Authors: Boonraksa Thidakul , Naisena Suparvadee 
Published: December 2021

Collocation is an often-neglected language form that foreign language teachers and students should focus on to achieve competence in a target language. In this research, the researchers studied purposely to facilitate both second language teachers and students to produce correct and appropriate collocations. The purposes of this research were 1) to study the collocation error levels of Bachelor of Arts English and Business English students studying at Northern Rajabhat University, 2) to study the relationship between first language (L1) and second language (L2) transfer collocation errors in students&rsquo; writing, and 3) to compare the collocation errors between high-proficiency students, medium- proficiency students and low-proficiency students. The research sample included 285 Thai EFL students enrolled in second-year English and Business English programs at Northern Rajabhat University during the first semester of the academic year 2021. The research instrument was a collocation proficiency test with 54 questions, which was divided into 2 sections: 1) 36 questions with 4 multiple-choice tests, and 2) 18 Thai to English translation questions. The items were chosen from the Oxford 3000&trade;, and were common vocabulary appearing in various contexts. Research data were analyzed using mean, standard deviation, t-test (Dependent), and Friedman test.
The research found that 1) the level of Grammatical Collocation errors of high-proficiency EFL students was at a moderate level, medium-proficiency and low-proficiency EFL students were at a high level, and for Lexical Collocation errors, all three groups of students were at a high level; 2) the EFL students&rsquo;collocation errors were caused by the language transfer from their first language (L1) to their second language (L2), synonyms, and lack of collocation competency; and 3) the most Lexical Collocation errors found in all student groups were Adverb + Adjective. For Grammatical Collocation, all groups could use Verb + Preposition better than Noun + Preposition, and the high proficiency and medium proficiency students could perform Adjective + Preposition the least, whilst the low proficiency students were better at Adjective + Preposition.
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Rosai-Dorfman Disease of Bone and Soft Tissue
Authors: Garcia Roberto A. , DiCarlo Edward F. 
Published: December 2021

Context.—
Rosai-Dorfman disease is a rare histiocytic proliferative disorder of unknown pathogenesis that may be diagnostically difficult in extranodal sites. It is commonly an unsuspected diagnosis when arising in bone and soft tissue, especially when it presents without associated lymphadenopathy. Its variable clinical presentation and nonspecific imaging findings make the diagnosis quite challenging, particularly in small biopsies. The problem is compounded by its less-characteristic histomorphologic features in comparison with nodal disease. Awareness of the potential diagnostic pitfalls in Rosai-Dorfman disease of bone and soft tissue should raise the degree of diagnostic accuracy.

Objective.—
To review the clinical manifestations, imaging characteristics, and histomorphologic features of Rosai-Dorfman disease of bone and soft tissue along with a brief discussion of its differential diagnosis, pathogenesis, and current management.

Data Sources.—
Thorough review of the literature with focus on clinical manifestations, imaging findings, key histomorphologic features, pathogenesis, and treatment.

Conclusions.—
The diagnosis of Rosai-Dorfman disease of bone and soft tissue may be quite challenging because of its variable clinical presentation and nonspecific imaging findings. It may be asymptomatic without systemic manifestations or associated lymphadenopathy. The definitive diagnosis relies on histopathologic identification of the characteristic S-100–positive histiocytes demonstrating emperipolesis. Bone and soft tissue lesions tend to have lower numbers of characteristic histiocytes and less conspicuous emperipolesis and often demonstrate areas of fibrosis or storiform spindle cell areas resembling fibrohistiocytic lesions. Awareness of these unusual features is necessary in order to consider Rosai-Dorfman disease in the differential diagnosis when confronting these rare and often misleading lesions.
Combination Therapy of Physical Activity and Dexamethasone for Cancer-Related Fatigue: A Phase II Randomized Double-Blind Controlled Trial
Authors: Yennurajalingam Sriram , Valero Vicente , Lu Zhanni , Liu Diane D. , Busaidy Naifa L. , Reuben James M. , Diaz Fleming Carolina , Williams Janet L. , Hess Kenneth R. , Basen-Engquist Karen , Bruera Eduardo 
Published: December 2021

Background: Despite the high frequency of cancer-related fatigue (CRF) and its debilitating effects on the quality of life of patients with advanced cancer, there are limited treatment options available. Treatments including physical activity (PA) or dexamethasone (Dex) improve CRF; however, they have lower adherence rates (PA) or long-term adverse effects (Dex). The aim of this study was to determine the feasibility of and preliminary results for the combination of PA and Dex in improving CRF. Methods: In this phase II randomized controlled trial, patients with advanced cancer and CRF scores of ≥4/10 on the Edmonton Symptom Assessment Scale were eligible. Patients were randomized to standardized PA for 4 weeks with either 4 mg of Dex (LoDex arm) or 8 mg of Dex (HiDex arm) twice a day for 7 days. Feasibility and change in the Functional Assessment of Cancer Illness Therapy-Fatigue subscale (FACIT-F) from baseline to day 8 and day 29 (primary outcome) were assessed. Secondary outcomes included changes in fatigue dimensions (FACIT-General, Patient-Reported Outcomes Measurement Information System [PROMIS]-Fatigue). Results: A total of 60 of 67 (90%) patients were evaluable. All patients were adherent to study medication. We found that 84% and 65% of patients in the LoDex arm and 96% and 68% of patients in the HiDex arm were adherent to aerobic and resistance exercise, respectively. The FACIT-F effect size in the LoDex arm was 0.90 (P<.001) and 0.92 (P<.001) and the effect size in the HiDex arm was 0.86 and 1.03 (P<.001 for both) at days 8 and 29, respectively. We found significant improvements in the Functional Assessment of Cancer Therapy-Physical (P≤.013) and the PROMIS-Fatigue (P≤.003) at days 8 and 29 in both arms. Mixed-model analysis showed a significant improvement in the FACIT-F scores at day 8 (P<.001), day 15 (P<.001), and day 29 (P=.002). Changes in the FACIT-F scores were not significantly different between patients in the 2 arms (P=.86). Conclusions: Our study found that the combination therapy of PA with Dex was feasible and resulted in the improvement of CRF. The improvement was seen for up to 3 weeks after the discontinuation of Dex. Further larger studies are justified.
ClinicalTrials.gov identifier: NCT02491632.
Una herramienta didáctica para la aplicabilidad del componente pragmático en E/LE
Authors: González Melón Eva 
Published: December 2021

Enseñar español implica algo más que cubrir contenidos léxico-gramaticales e introducir a los alumnos en la herencia cultural o histórica del país que lo acoge. Olvidar que una lengua se inscribe en unas coordenadas pragmático-sociales tiende a convertirse con frecuencia en una asignatura pendiente en la enseñanza de una lengua extranjera, dada la subjetivad que entraña su tratamiento en el aula. La necesidad de concienciación de que nuestros estudiantes adquieran una competencia pragmático-intercultural[1]—además de una meramente lingüística— empieza a pesar sobre los hombros del profesor de E/LE por falta de herramientas didácticas específicas. Por todo ello, este artículo describe y presenta el funcionamiento del método RICA­ que pretende servir de apoyo para la comunidad docente y ofrecer un recurso para la enseñanza del componente pragmático.

[1]Según el MCERL (2002) “el alumno […] se convierte en plurilingüe y desarrolla una interculturalidad. Las competencias lingüística y cultural respecto a cada lengua se modifican mediante el conocimiento de la otra lengua y contribuyen a crear una conciencia, unas destrezas y unas capacidades interculturales” (MCERL, 2002, p. 47).
Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA
Authors: Lee Yo Han , Jang Hyun-Jun , Kim Sounkou , Choi Sun Sil , Khim Keon Woo , Eom Hye-jin , Hyun Jimin , Shin Kyeong Jin , Chae Young Chan , Kim Hongtae , Park Jiyoung , Park Neung Hwa , Woo Chang-Yun , Hong Chung Hwan , Koh Eun Hee , Nam Dougu , Choi Jang Hyun 
Published: December 2021

Background:Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation and imbalances in lipid metabolism in the liver. Although nuclear receptors (NRs) play a crucial role in hepatic lipid metabolism, the underlying mechanisms of NR regulation in NAFLD remain largely unclear.Methods:Using network analysis and RNA-seq to determine the correlation between NRs and microRNA in human NAFLD patients, we revealed that MIR20B specifically targets PPARA. MIR20B mimic and anti-MIR20B were administered to human HepG2 and Huh-7 cells and mouse primary hepatocytes as well as high-fat diet (HFD)- or methionine-deficient diet (MCD)-fed mice to verify the specific function of MIR20B in NAFLD. We tested the inhibition of the therapeutic effect of a PPARα agonist, fenofibrate, by Mir20b and the synergic effect of combination of fenofibrate with anti-Mir20b in NAFLD mouse model.Results:We revealed that MIR20B specifically targets PPARA through miRNA regulatory network analysis of nuclear receptor genes in NAFLD. The expression of MIR20B was upregulated in free fatty acid (FA)-treated hepatocytes and the livers of both obesity-induced mice and NAFLD patients. Overexpression of MIR20B significantly increased hepatic lipid accumulation and triglyceride levels. Furthermore, MIR20B significantly reduced FA oxidation and mitochondrial biogenesis by targeting PPARA. In Mir20b-introduced mice, the effect of fenofibrate to ameliorate hepatic steatosis was significantly suppressed. Finally, inhibition of Mir20b significantly increased FA oxidation and uptake, resulting in improved insulin sensitivity and a decrease in NAFLD progression. Moreover, combination of fenofibrate and anti-Mir20b exhibited the synergic effect on improvement of NAFLD in MCD-fed mice.Conclusions:Taken together, our results demonstrate that the novel MIR20B targets PPARA, plays a significant role in hepatic lipid metabolism, and present an opportunity for the development of novel therapeutics for NAFLD.Funding:This research was funded by Korea Mouse Phenotyping Project (2016M3A9D5A01952411), the National Research Foundation of Korea (NRF) grant funded by the Korea government (2020R1F1A1061267, 2018R1A5A1024340, NRF-2021R1I1A2041463, 2020R1I1A1A01074940, 2016M3C9A394589324), and the Future-leading Project Research Fund (1.210034.01) of UNIST.