bluuebunny/crossref_metadata_2025_split huggingface dataset:
Active Cytomegalovirus Infection in Acute Respiratory Distress Syndrome Patients: Incidence, Risk Factors, and Clinical Outcomes
Authors: Zhang Zhihui , Li Rujian , Zheng Yongxin , Zhan Qianyi , Zang Qing , Zhao Ruixue , Rao Qing , Zhang Jierong , Huang Yongbo , Liu Xiaoqing , Li Yimin 
Published: June 2021

Abstract
Background: Acute respiratory distress syndrome (ARDS) patients have been reported to have a high seroprevalence of cytomegalovirus (CMV). However, the role of active CMV infection in ARDS patients has not been clearly established.Objective: This study aimed at determining the incidence, risk factors, and clinical outcomes of active cytomegalovirus (CMV) infection in acute respiratory distress syndrome (ARDS) patients.Methods: We retrospectively reviewed medical records for ARDS patients who had been admitted to the intensive care unit (ICU) from January 1st, 2018 to December 31st, 2020 at a national teaching hospital in China. Study participants were divided into active CMV infection and non-active infection groups based on CMV DNAemia within a 28-day hospitalization period in ICU. Clinical features, laboratory findings, treatment measures, and clinical outcomes were compared between the two groups.Results: Among 168 ARDS patients, 31 (18.5%) exhibited active CMV infection within the 28-day hospitalization period in ICU. In multivariate logistic regression analysis, monocyte counts, hemoglobin levels, blood transfusion, and septic shock were significantly independently associated with active CMV infection (p < 0.05). Oxygenation (PaO2/FiO2) of active CMV infection patients was worse than for non-active CMV infection (p < 0.05). Duration of invasive mechanical ventilation, 28-day ventilator-free days, length of ICU stay, and 28-day all-cause mortality rates in active CMV infection patients were significantly higher than in those without active CMV infection (p < 0.05).Conclusions: Active CMV infection is common among critically ill ARDS patients. Monocytes, hemoglobin, blood transfusion, and septic shock are risk factors for active CMV infection, which has a negative effect on oxygenation. Moreover, active CMV infection is associated with several adverse prognoses. Prospective studies should be performed to evaluate the impact of prophylactic antiviral therapy for prognoses among ARDS patients.
Determinants of adherence to iron-folic acid supplementation among postnatal mothers in Addis Ababa referral hospitals, Ethiopia
Authors: Taye Tigist Alemu , Sinaga Mesele , Taye Abonesh 
Published: June 2021

Abstract
Abstract: In Ethiopia, adherence to iron-folic acid supplementation is disappointingly low were only 5% took more than 90 tablets during their pregnancy; however, only limited data are available on the determinant factors of non-adherence. Therefore, the aim of this study was to identify determinants of adherence to iron-folic acid supplementation among postnatal mothers in three referral hospitals of Addis Ababa, Ethiopia.Purpose:Methods: An institutional based unmatched case-control study was conducted on 240 women who have been at postnatal care. Data were collected using interviewer administered questionnaire. Data were entered and analyzed using EpiData and SPSS version 20.0, respectively. Bivariate and multivariate logistic regressions were employed to identify the determinants at p-value < 0.25 and < 0.05 respectively.Results: The major determinant factors of adherence to iron-folic acid supplementation were, mothers age group 29-33 [AOR=1.66, 95% CI: 2.010-0.0492], ANC initiation time [AOR=4.21, 95% CI: 2.3-10.6], counseling on IFAS [AOR=3.89, 95% CI: 1.8-8.4], time taken to travel to health facility [AOR=3.17,95% CI:1.35-7.4], gravidity [AOR=2.08,95%CI:1.06-4.09], morning sickness [AOR 0.33, 95% CI: 0.15-0.69] and planned pregnancy [AOR=4.2, 95%CI: 1.6-10.9].Conclusion: This study highlighted age of participants, planned pregnancy, antenatal care initiation time, morning sickness, gravidity, counseling and distance to health facility are factors that have independently associate with adherence. Counseling should be given for clients on the correct dosage and duration of supplementation for prevention of anemia and neural tube defects.
For evidence-based clinical long-term follow-up of childhood cancer survivors, risk stratification is required
Authors: Klingensmith James D. 
Published: June 2021

Abstract
The National Cancer Survivorship Initiative (NCSI) advocated reorganizing clinical follow-up care in England depending on cancer type and therapy, with levels ranging from Level 1 (assisted self-management) to Level 3 (intensive follow-up) (consultant-led care). The goal of this research was to use a large population-based cohort of pediatric cancer survivors to investigate the risks of major adverse health outcomes related with NCSI Levels of clinical treatment. SPNs—5 percent (two-fold expected), 14 percent (four-fold expected), and 21 percent (eight-fold expected) by 45 years from diagnosis among non-leukaemic survivors assigned to NCSI Levels 1, 2, and 3; non-neoplastic death—2 percent (two-fold expected), 4 percent (three-fold expected), and 8 percent (seven-fold expected); non-fatal infections—2 percent (two-fold expected), 4 percent (three-fold expected); non- As a result, the total cumulative risks of any negative health outcome were 21%, 45%, and 69%, respectively. Despite its simplicity, the risk stratification tool offers evident and substantial discrimination in terms of long-term cumulative and excess risks of major unfavorable outcomes between survivors allocated to various NCSI Levels.
Application of ImageJ Software for the Quantification of Hand Joint
Space Narrowing in Patients with Rheumatoid Arthritis
Authors: Minh Nui Nguyen , Nguyen Nga Phi Thi , Ngoc Chau Nguyen , Duy Tien Tran , Huy Thong Nguyen , Do Binh Nhu , Viet Tien Tran 
Published: June 2021

Background:
ImageJ software is used to quantify the joint space width (JSW) of hand
and wrist in patients with rheumatoid arthritis (RA) as well as in the healthy control group.

Method:
Forty-one RA patients and 31 healthy controls were included in this study. All of 72 participants
underwent digital radiography of the bilateral hand and wrist; then, all the images were
opened by ImageJ software to measure the width of wrist and hand joint space (total 2160 joints).
Joint space narrowing (JSN) was defined if the width was less than the mean - 2SD of the control
group.

Result:
The mean JSW of all sites of wrist and hand joints of RA patients were significantly reduced
as compared to those in the control group (p<0.001). There were 37/41 (90.24%) RA patients
who had JSN in at least one joint in hand or wrist. In total, 70.89% of joints on the right and
68.46% of joints on the left wrist and hand had JSN.

Conclusion:
ImageJ software is simple and convenient that helps rheumatologists quantify the
width of joint space for diagnosis and follow-up in RA patients.
Relationship between Gentamicin Administration and Ductal Patency in
Very Low Birth Weight Infants
Authors: Cakir Ufuk , Tayman Cuneyt 
Published: June 2021

Background:
Patent Ductus Arteriosus (PDA) is associated with adverse clinical outcomes
in very low birth weight (<1500g) infants.

Objective:
In our study, it was aimed to investigate the effect of gentamicin treatment, which is frequently
used for early-onset sepsis on ductal patency.

Method:
We performed a single-center retrospective review of charts of preterm infants <32
weeks gestation with birth weight <1500 grams born between June 1, 2015 and December 31, 2019
at the neonatal intensive care unit. All infants underwent an echocardiogram (ECHO) at 72 hours.
To determine the effect of gentamicin treatment on hemodynamically significant PDA (hsPDA),
we compared the frequency and duration of gentamicin administration between infants with hsPDA
and without hsPDA.

Results:
During the study period, 792 patients were evaluated. Gentamicin was given to more infants
with hsPDA than to those without hsPDA (89.2% vs. 64.6%, p<0.001), and the duration of
therapy was longer in those infants with hsPDA (7 days vs. 9 days, p<0.001). The area under the
curve for duration of gentamicin was 0.772 (%95 CI: 0.742-0.804, P=0.0001), sensitivity: 59 (%95
CI: 53-65), specificity: 82 (%95 CI: 78-88), with a cut-off day for duration of gentamicin >7 days.

Conclusion:
In our study, it was found that ductal contraction decreased and hsPDA rate increased
as the rate and duration of gentamicin increased.
Developing a Standardized Review Process of Pharmacogenomics Resources for Psychotropic Medications
Authors: Stoneberg Maja , Petry Natasha , Grindeland Carlina , Roemmich Monte , Massmann Amanda , Baye Jordan , Schultz April 
Published: June 2021

Background:
The impact of personalized medicine is potentially enormous, but the genetic
results are often difficult to integrate into health settings. A number of research studies are
emerging to aid in translating pharmacogenomics into clinical practice.

Objective:
We aimed to create a standardized process to guide the implementation of dose adjustment
recommendations into the electronic health record (EHR).

Materials and Methods:
Monographs were created for selected drug-gene pairs, allowing for a
standardized review of available evidence. A scoring template was developed to assess whether the
evidence presented in the drug monograph qualified the mentioned drug-gene pair for Clinical Decision
Support (CDS) within the EHR.

Results:
Of nine medications reviewed, only one drug-gene pair qualified for a CDS proposal to
the institution’s governing pharmacogenomics committee.

Conclusion:
This project resulted in the development of a standard process for reviewing pharmacogenomics-
related literature, allowing for more CDS proposals to be accepted.
Importancia y Efectos De La Sentencia T-194 De 1999
Authors: Arismendy Martínez Oscar , Kerguelén Durango Eduardo , Alarcón Orlando Ramón , Ruiz Mestra Javir 
Published: June 2021

El veinticinco (25) de marzo de mil novecientos noventa y nueve (1999), la Sala Cuarta de Revisiónde Tutelas de la Corte Constitucional, profirió la sentencia T 194 de 1999 sobre la acción de revisiónde las sentencias proferidas por el Tribunal Superior del Distrito Judicial de Montería y la CorteSuprema de Justicia en el trámite del proceso radicado bajo el número T 175.217. en contra de laCorporación E léctr ica de la Costa Atlántica CORELCA ––, y la sociedad de economía mixta,comercial e industrial del Estado Empresa Multipropósito Urrá S.A., en la cual se estimó laspeticiones de Álvaro León Obando Moncayo 3 en nombre y representación de los afiliados a laAs ociación de Productores para el Desarrollo Comunitario de la Cié naga Grande de LoricaASPROCIG de solicitar ordenar a las entidades demandadas: 1) suspender las actividades que losvulneran; 2) iniciar la ejecución de los proyectos de compensación y miti gación; 3) adelantar losestudios de impacto que se omitieron; 4) poner en práctica los planes de manejo, mitigación ycompensación con participación efectiva de la comunidad, y 5) suspender el llenado de la presa hastaque se adopten las medidas necesaria s para no causar más daño a la población y el medio ambiente.En general, la Corte revocó parcialmente los fallos proferidos por la Sala de Casación Penal de laCorte Suprema de Justicia el 8 de septiembre de 1998 y la Sala Penal del Tribunal Superior del DistritoJudicial de Montería el 3 de julio de 1998 dando razón a los peticionarios y, en su lugar, tutelo losderechos de los afiliados a la Asociación de Productores para el Desarrollo Comunitario de la CiénagaGrande de Lorica ASPROCIG --, a la participa ción y a un medio ambiente sano; y confirmó lasentencia de segunda instancia, en cuanto negó el amparo de los derechos a la vida, la salud y eltrabajo. Bajo esta perspectiva, esta investigación pretende analizar la importancia y efectos de estefallo en la sociedad, en especial, por lo s límites que en él se fija a los organismos de control y laratificación de la capacidad sancionadora que los órganos adm inistrativos locales tienen sobre lasafectaciones por la construcción de las obras civiles de la hidroeléctrica Urrá I, y la desviación del ríosinú.
El abordaje del trabajo se hizo desde mecanismos alternativos al principio de proporcionalidad parajust ificar la preferencia de un derecho sobre otro resultante de un proceso ponderativo, y que la teoríade impacto del activismo judicial de McCann (1994), Feeley y Rubin (1998), Gerald Rosenberg(1991) y Cesar Rodríguez (2012) son un buen ejemplo de ello , en tal sentido, nuestra idea es que elactivismo judicial, puede ser, al menos en algunos casos, o en relación a algunos aspectos, altamentesatisfactorio.
KEHIDUPAN SOSIAL EKONOMI PETANI NILAM DI DESA TAIKAKO, KEC. SIKAKAP, KAB. KEPULAUAN MENTAWAI
Authors: Murni Yanti , Ansofino Ansofino , Meldawati Meldawati 
Published: June 2021

Desa Taikako is a village form three villages in Kecamatan Sikakap, Kabupten Kepulauan Mentawai. Most of the population is a traditional farmer with kinds of commodities such as coconut, clove, banana, taro and sago. Since 1960 when patchouli is popular in farmer and significance prices in 1997 was improve the economy of farmers. This article describe the growth of patchouli cultivation, socio-economic situation of farmers in Taikako during 1997-2010. Result is the patchouli cultivation well developed in terms of cultivation and plant area. These developments affected the patchouli price. The development of cultivation of patchouli effected to social and economic life of farmers in the period 1997-2010. Desa Taikako merupakan salah satu desa dari tiga desa yang berada di Kecamatan Sikakap, Kab. Kepulauan mentawai. Sebagian besar penduduknya adalah petani tradisional dengan jenis komoditi seperti kelapa, cengkeh, pisang, keladi, sagu. Masuknya tanaman nilam pada tahun 1960-an dan mengalami kenikan harga yang signifikan pada tahun 1997 telah meningkatkan ekonomi petani. Artikel ini akan menjelaskan perkembangan usaha budidaya tanaman nilam, keadaan sosial ekonomi petani nilam di Desa Taikako selama periode 1997-2010. Hasil penelitian menunjukkan bahwa usaha budidaya tanaman nilam di Desa Taikako mengalami perkembangan dengan baik dalam hal budidaya dan luas tanaman yang dikelola. Perkembangan tersebut dipengaruhi oleh nilai jual minyak nilam di pasaran. Perkembangan budidaya tanaman nilam berpengaruh positif terhadap kehidupan sosial ekonomi petani dalam periode 1997-2010.
Hubungan Lingkungan Keluarga Terhadap Hasil Belajar Sosiologi Di SMA Negeri 16 Padang
Authors: Rahayu Sri 
Published: June 2021

The result of semester mid-test in Academic Year 2014/2015 in sociology subject is low level. Base on te result, this study focused on influence of family environment to study result on sociology at SMA Negeri 16 Padang. This study uses a quantitative method with ex-post facto study approach. The population is 123 sociology students from class X of SMA Negeri 16 Padang, and sample is 44 students. Sampling was done by proportional random sampling technique. The research variables consist of a family environment variables (X) and variable Learning Outcomes (Y). data was collected through questionnaires. Questionare validity was tested by using the formula product moment correlation and reliability of the instrument was calculated using Cronbach Alpha formula. Prior to the data analysis first conducted the testing requirements analysis including normality test, homogeneity test. The data analysis technique used to test the hypothesis is the product moment correlation analysis technique. The results showed that: There is a significant positive effect between family environment and learning outcomes where the results count r is 0.423, greater than 0.266 ta­bles.. The results showed the better family environment will improve student learning outcomes.Hasil ujian tengah semester siswa pada Tahun Pelajaran 2014/2015 berada pada lelevel rendah pada mata pelajaran sosiologi. Atas dasar masalah tersebut penelitian ini difokuskan pada pengaruh lingkungan keluarga terhadap hasil belajar sosiologi di SMA Negeri 16 Padang. Penelitian ini menggunakan pendekatan kuantitatif. Jenis penelitian ini termasuk penelitian ex-post facto. Populasi penelitian ini adalah siswa kelas X SMA Negeri 16 Padang yang belajar mata pelajaran sosiologi yang berjumlah 123 orang. Dengan jumlah sampel sebanyak 44 orang siswa. Pengambilan sampel dilakukan dengan teknik proportional random sampling. Variabel penelitian terdiri dari variabel lingkungan keluarga (X) dan Variabel Hasil Belajar (Y). Data dikumpulkan melalui angket. Validitas angket dilakukan dengan mengunakan rumus korelasi product moment dan reabilitas instrumen dihitung dengan menggunakan rumus Alpha Cronbach. Sebelum dilakukan analisis data terlebih dahulu diadakan pengujian persyaratan analisis yang meliputi uji normalitas, uji homogenitas. Teknik analisis data yang dipakai untuk menguji hipotesis adalah dengan teknik analisis korelasi product moment. Hasil penelitian menunjukkan bahwa: Terdapat pengaruh positif signifikan antara lingkungan keluarga dengan hasil belajar sosiologi dimana hasil r hitung 0.423 lebih besar dari r tabel 0.266. Hasil penelitian menunjukkan semakin baik lingkungan keluarga maka akan meningkatkan hasil belajar siswa.
Dynamic simulation of a high altitude gantry crane with cable hoisting. Part one. 2D model
Authors: Jafari Mostafa , Kudryavtsev Evgeniy M. 
Published: June 2021

Introduction. Simulation of the 2D dynamic motion of a high altitude wide span gantry crane with a rope hoisting mechanism is addressed. Such large gantry cranes with a height of more than 50 meters, have been unstudied very well so far. A small swing angle of the payload, it's fast hoisting, and the fast motion of the trolley are critical for these cranes and, hence, they need to be analyzed in detail.
Materials and methods. The generalized formulation of the two-dimensional crane dynamics is efficiently performed and simulated in Mathcad. This is a single mass model that has a non-elastic cable. The formulation is derived using the Lagrange method, and differential equations are correctly solved using the Runge-Kutta method in Mathcad. In this model the crane is fixed, and all the subsystems are considered as rigid bodies without any deflection in terms of the trolley and the payload.
Results. The results are verified using MSC ADAMS (Academic) that indicates satisfactory convergence. The considerable influence of the payload oscillation on the trolley motion is visible in both Mathcad and ADAMS models. The implemented Mathcad code can be useful for students and researchers.
Conclusions. The maximum speed of the trolley is 1.716 m/s to prevent the payload swinging angle from exceeding 0.5 deg. The calculated velocity of the trolley is reasonable for such a large crane if limitations like wind effects and resonance are ignored.
Dampak Moderasi Locus of Control terhadap Efektivitas Sistem Informasi Keuangan pada Kantor Kecamatan di Kota Semarang, Provinsi Jawa Tengah
Authors: Septiawati Rohma , Astriani Devi , Kiryanto Kiryanto 
Published: June 2021

The purpose of this study was to analyze the impact of locus of control moderation, the factors that affect the financial information system at the sub-district office in the city of Semarang. This study's population was 16 Districts Offices in Semarang City and obtained 54 questionnaires, then analyzed moderating regression analysis (MRA). From the research results of the impact of Locus of Control Moderation on the Effectiveness of Financial Information Systems at the District Office in Semarang City, Central Java Province, the results of the research on the first hypothesis, the influence of top management on the effectiveness of information systems, are to examine the influence of user satisfaction on the effectiveness of information systems, to examine the influence of organizational culture on the effectiveness of information systems. The effectiveness of information systems, to examine the effect of locus of control on the relationship between top management on the effectiveness of information systems, to examine the effect of locus of control between user satisfaction on the effectiveness of information systems from the results of the research resulted that it has a positive and significant effect. Tujuan penelitian ini adalah untuk menganalisis pengaruh moderasi locus of control, faktor-faktor yang mempengaruhi sistem informasi keuangan pada kantor kecamatan di kota Semarang. Populasi penelitian ini adalah 16 Kantor Kecamatan di Kota Semarang dan diperoleh 54 kuesioner, kemudian dianalisis analisis regresi moderasi (MRA). Dari hasil penelitian pengaruh Locus of Control Moderation terhadap Efektifitas Sistem Informasi Keuangan pada Kantor Kecamatan Kota Semarang Provinsi Jawa Tengah diperoleh hasil penelitian hipotesis pertama yaitu pengaruh manajemen puncak terhadap efektivitas sistem informasi, untuk menguji pengaruh kepuasan pengguna terhadap efektivitas sistem informasi, untuk menguji pengaruh budaya organisasi terhadap efektivitas sistem informasi. Efektivitas sistem informasi, untuk menguji pengaruh locus of control terhadap hubungan antara manajemen puncak terhadap efektivitas sistem informasi, untuk menguji pengaruh locus of control antara kepuasan pengguna terhadap efektivitas sistem informasi dari hasil penelitian menghasilkan pengaruh yang positif dan signifikan
Analisis Fraud Pentagon Terhadap Kecurangan Laporan Keuangan Pada Sektor Perusahaan Manufaktur
Authors: Yanti Delviana Dama , Munari Munari 
Published: June 2021

The purpose of this research is to see the effect of pentagon fraud that proxied by financial targets, nature of the industry, quality of external auditors, change of auditors, number of CEOs who frequently detect fraud in financial statements. Financial statement fraud in this study was measured using the proxies of Return on Assets, Receivables, selection of audit services at public accounting firms, changes in public accounting firms, changes in directors, and the number of CEO photos. The population in research study are use manufacturing companies who listed on the Indonesia Stock Exchange (BEI) in 2017-2019. This research uses a purposive sampling technique so, there are 48 financial reports from 25 manufacturing companies. The analytical method used in this research is multiple linear regression analysis with SPSS version 20. The results of this research indicate that financial targets, nature of industry, quality of external auditors and the number of CEOs who often don’t have a significant effect in the handling of fraudulent financial statements. Meanwhile, changes in auditors and changes in direction have a significant effect from pentagon fraud side on fraudulent financial statements.Tujuan penelitian ini adalah untuk menganalisis pengaruh moderasi locus of control, faktor-faktor yang mempengaruhi sistem informasi keuangan pada kantor kecamatan di kota Semarang. Populasi penelitian ini adalah 16 Kantor Kecamatan di Kota Semarang dan diperoleh 54 kuesioner, kemudian dianalisis analisis regresi moderasi (MRA). Dari hasil penelitian pengaruh Locus of Control Moderation terhadap Efektifitas Sistem Informasi Keuangan pada Kantor Kecamatan Kota Semarang Provinsi Jawa Tengah diperoleh hasil penelitian hipotesis pertama yaitu pengaruh manajemen puncak terhadap efektivitas sistem informasi, untuk menguji pengaruh kepuasan pengguna terhadap efektivitas sistem informasi, untuk menguji pengaruh budaya organisasi terhadap efektivitas sistem informasi. Efektivitas sistem informasi, untuk menguji pengaruh locus of control terhadap hubungan antara manajemen puncak terhadap efektivitas sistem informasi, untuk menguji pengaruh locus of control antara kepuasan pengguna terhadap efektivitas sistem informasi dari hasil penelitian menghasilkan pengaruh yang positif dan signifikan.