bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute Respiratory Distress Syndrome Caused By Human Adenovirus In Adults: A Prospective Observational Study In Guangdong, 2019–2020
Authors: Wu Zhan , Zhang Rong , Liu Dongdong , Liu Xuesong , Zhang Jierong , Zhang Zhihui , Chen Sibei , He Weiqun , Li Yimin , Xu Yonghao , Liu Xiaoqing 
Published: August 2021

Abstract
Background: Viral causes of acute respiratory distress syndrome (ARDS) are mostly limited to influenza. However, adenovirus has been emerging as a cause of ARDS with a high mortality rate and described in adults are rare.Methods: We conducted a prospective, single-center observational study of viral pneumonia with ARDS and confirmed adenovirus-associated ARDS in adults at our quaternary referral institution between March 2019 and June 2020. We prospectively analyzed clinical characteristics, laboratory test results, radiological characteristics, viral load from nasopharyngeal swabs and endotracheal aspirates, treatments, and outcomes for the study participants.Results: The study enrolled 143 ARDS patients, including 47 patients with viral pneumonia-related ARDS, among which there were 14 adenovirus-associated ARDS patients, which accounted for 29.79% of the viral pneumonia-related ARDS cases. Among the adenovirus-associated ARDS patients, 78.57% were men with a mean age of 54.93 ± 19.04 years. Adenovirus-associated ARDS patients had no specific clinical characteristics, but they presented with shortness of breath and fever, and their initial chest radiographic findings were multifocal or showed diffuse opacity. The viral load and the positivity rate in the lower respiratory tract were higher than that of the upper respiratory tract in the patients with adenovirus-associated ARDS, and 85.71% of the patients had a significant decrease in the number of CD3+CD4+ T cells during the early stage. All patients required invasive mechanical ventilation treatment. The average time from shortness of breath to the application of invasive ventilation was 24 hours. The median duration of invasive mechanical ventilation was 22 days (14–75 days). Six patients (42.86%) required renal replacement therapy, and three patients (21.43%) required extracorporeal membrane oxygenation support. Additionally, 85.71% of the 14 adenovirus-associated ARDS patients survived.Conclusion: Adenovirus infection is an important cause of virus-related ARDS. The positivity rate of adenovirus infection in lower respiratory tract secretions was higher than that in upper respiratory tract secretions in these patients. Most of the patients had a significant decrease in the number of CD3+CD4+ T cells during the early stage. Early identification and intervention to prevent disease progression are essential for reducing the mortality rate in these patients.Trial registration: ChiCTR1900022822. Registered 27 April 2019, https://www.chictr.org.cn/showproj.aspx?proj=38064
Support Vector Machine for Stock Movement Direction Prediction with Sparsity for Feature Selection
Authors: Miao Maoxuan , Wu Jinran , Cai Fengjing , Fu Liya , Wang You-Gan 
Published: August 2021

Abstract
In the stock market, accurate prediction of stock price movement direction can effectively increase the profits for investors. However, the stock price is an extremely complex dynamic system with strong fluctuation, proper selection of technical indicators can potentially improve the accuracy of the direction prediction. We propose a novel sparse least squares support vector machine (LSSVM) by combining recursive feature elimination (RFE) and Relief via a weight parameter. Specially, the benefit if this hybrid is three fold: (1) accounting for any intrinsic correlations among the features, (2) more effective prediction due to the sparse framework capable of removing some “noise” features completely; and (3) simultaneously select technical indicators according to the feature ranking and accounts for possible interactions and possible non-linear effects among the features. Three stock datasets from the liquor and spirits concept are analyzed to demonstrate the superiority of our proposed new framework providing sparse solutions resulting in more accurate predictions and higher returns among all seven considered classifiers.
Overview of National Health Reporting in the EU and Quality Criteria for Public Health Reports – Results of the Joint Action InfAct
Authors: Thissen Martin , Seeling Stefanie , Achterberg Peter , Fehr Angela , Palmieri Luigi , Tijhuis Mariken J. , Unim Brigid , Ziese Thomas 
Published: August 2021

Abstract
Background: Health reporting shall provide up-to-date health-related data to inform policy-makers, researchers and the public. To this end, health reporting formats should be tailored to the needs and competencies of the target groups and provide comparable and high-quality information. Within the Joint Action on Health Information ‘InfAct’, we aimed at gaining an overview of health reporting practices in the EU Member States and associated countries, and developed quality criteria for the preparation of public health reports. The results are intended to facilitate making health information adequately available while reducing inequalities in health reporting across the EU.Methods: A web-based desk research was conducted among EU Member States and associated countries to generate an overview of different formats of national health reporting and their respective target groups. To identify possible quality criteria for public health reports, an exploratory literature review was performed and earlier projects were analysed. The final set of criteria was developed in exchange with experts from the InfAct consortium. Results: The web-based desk research showed that public health reports are the most frequently used format across countries (94%), most often addressed to scientists and researchers (51%), politicians and decision-makers (41%). However, across all reporting formats, the general public is the most frequently addressed target group. With regards to quality criteria for public health reports, the literature review has yielded few results. Therefore, two earlier projects served as main sources: the ‘Evaluation of National and Regional Public Health Reports’ and the guideline ‘Good Practice in Health Reporting‘ from Germany. In collaboration with experts, quality criteria were identified and grouped into eight categories, ranging from topic selection to presentation of results, and compiled in a checklist for easy reference.Conclusion: Health reporting practices in the EU are heterogeneous across Member States. The assembled quality criteria are intended to facilitate the preparation, dissemination and access to better comparable high-quality public health reports as a basis for evidence-based decision-making. A comprehensive conceptual and integrative approach that incorporates the policy perspective would be useful to investigate which dissemination strategies are the most suitable for specific requirements of the targeted groups.
Tracking Excess of Maternal Deaths Directly and Indirectly Associated With COVID-19 in Brazil: A Nationwide Database Analysis
Authors: Guimarães Raphael Mendonça , Reis Lenice Gnocchi Costa , Gomes Maria Auxiliadora Souza Mendes , Magluta Cynthia , de Freitas Carlos Machado , Portela Margareth Chrisostomo 
Published: August 2021

Abstract
Background
The COVID-19 pandemic brought a new challenge to maternal mortality in Brazil. Throughout 2020, Brazil registered 549 maternal deaths, mainly concentrated in second and third-trimester pregnant women. The objective of this study was to verify the excess of maternal deaths that occurred in Brazil caused directly and indirectly by Covid-19 in the year 2020. In addition, we sought to identify clinical social and health care factors associated with these maternal deaths, when they were directly caused by Covid-19.
Methods
We performed nationwide analyses, based on data from the Mortality Information System (SIM), for general deaths and maternal deaths, and the Influenza Epidemiological Surveillance System (SIVEP-Influenza), for estimates of female and maternal deaths due to COVID-19. The methodological approach adopted two distinct techniques. First, we estimated the excess maternal mortality and the breakdown of the excess between total and COVID-19 deaths. Then, we estimated the odds ratios of occurrence of symptoms, comorbidities, social determination proxies, and hospital care aspects between COVID-19 maternal and childbearing age female deaths. We chose women of childbearing age (15 to 49 years) as a reference because sex and age introduce differentials in the risk of COVID-19 death.
Results
Most of maternal deaths occurred during pregnancy in all months of 2020 (µ = 59.8%, SD = 14.3%, range 50%-100%). Even considering the excess mortality due to COVID-19 for the childbearing age female population, maternal mortality was more penalized. Clinical variables suggest that the chances of occurrence of symptoms among maternal deaths were like those observed in the deaths of women of childbearing age. On the other hand, the odds of being a black woman, living in a rural area and being hospitalized out of the residence municipality among maternal deaths were 44%, 61%, and 28% higher than control group. Odds of hospitalization, ICU admission, and invasive ventilatory support use among maternal deaths were, respectively, 4.37, 1.73, and 1.64 times as control group.
Conclusions
Differences between the two groups of deaths are significantly associated with social determination and (in)adequate obstetric care. Year 2021 has been more severe for maternal mortality. We need to increase immunization and monitoring among pregnant women immediately.
Integration of Satellite Observation and Dust Trajectory Modeling for Dust Transport and Dispersion Monitoring
Authors: Alizadeh Faezeh , Falahatkar Samereh , Afzali Afsaneh 
Published: August 2021

Abstract
Land use/cover change was distinguished as one of the most local environmental consequences and has an important role in increasing dust due to land degradation. The aim of study was to identify the local dust storm sources in Khuzestan province (southwestern Iran) due to land use/cover change and their dispersion and transport modeling from these sources by Lagrangian particle HYSPLIT model. In the first part of study, Landsat images for 1984, 1992, 2002, and 2017 were used in order to produce the land use/cover maps and post classification comparison was applied for land use/cover change detection from 1984 to 2017. The results of change detection showed that wetland areas (Horolazim wetland and Shadegan international wetland) experienced sever changes and converted to probable dust storm centers. Subsequently, HYSPLIT model was performed in dust trajectory modeling from the detected dust storm centers for 365 days of 2016 in three elevation level. Aerosol optical depth (AOD) product of MODIS and air quality monitoring(AQM) data were used for HYSPLIT performance assessment. The findings of modeling showed that storms originated from detected dust storm centers can be transferred to the transboundary of Khuzestan province, especially in hot season. Therefore, focusing on national programs could be as valuable as international cooperation for mitigation and controlling dust storms in southwestern Iran.
Burden of Liver Cancer Attributable to Five Risk Factors by Specific Etiologies in 204 Countries and Territories
Authors: Li Yizhen , Wei Bajin , Deng Yujiao , Liu Yuanxing , Deng Xinyue , Xiang Dong , Hu Jingjing , Zheng Yi , Xu Peng , Yao Jia , Zhai Zhen , Zhou Linghui , Yang Si , Wu Ying , Zheng Shusen , Dai Zhijun 
Published: August 2021

Abstract
Background Liver cancer has caused a serious disease burden worldwide wherein prognostic risk factors may have had a significant role. However, previous studies have focused on liver cancer distributions and trend variations without analyzing the role of risk factors. Methods We assessed liver cancer burden attributable to five recognized risk factors as well as temporal trends from 1990 to 2019 based on the 2019 Global Burden of Disease Study. The risk exposure levels and their contributed burden were estimated by cause, sex, age, and location. Furthermore, the relationship between the risks and social-demographic index (SDI) was investigated. Results The total liver cancer burden attributable to risk factors is still increasing year by year in terms of death and disability-adjusted life years. However, the burden attributable to alcohol use and smoking has shown a downward trend in recent years. Risk-related burden in males was more than three times as that in females, the burden among the middle-aged and elderly was the most serious, and Central Asia, high-income Asia Pacific and East Asia exhibited the highest burden worldwide. The exposure levels of the five recognized risk factors were generally positively correlated with SDI value. However, the risk-related liver cancer burden first increased and then decreased with the SDI value. Conclusion These findings could help in understanding the role of prognostic risk factors in liver cancer burden, in promoting the development of relevant studies, and in proposing better prevention and control policies tailored to local conditions.
CERTAIN Program: Logic Model for System Level Planning and Evaluation of Innovative Education Delivery and Dissemination
Authors: Sun Yuqiang , Li Heyi , Tekin Aysun , Bogojevic Marija , Flurin Laure , Heise Katherine , Kashyap Rahul , Finch Alexander , Niven Alexander , Gajic Ognjen , Dong Yue 
Published: August 2021

Abstract
Background

CERTAIN (Checklist for Early Recognition and Treatment of Acute Illness and iNjury) has been shown to improve critical care process and patient outcomes in international ICUs with variable resources.
Methods

CERTAIN education program derived from this approach is designed, promoted, and implemented following the Logic model. Through the roadmap of the Logic model, we presented a dynamic, longitudinal implementation framework that had sufficient rigor yet offers flexibility to reach the need of the existing and emerging diversified medical education projects.
Results

Using the Logic model, the delivery of the CERTAIN education program is optimized to deliver relevant education content in various environments. During the COVID-19 outbreak, the implementational framework demonstrated that it could serve as an excellent template for effective response to global pandemics.
Conclusions

The Logical model is useful as a facilitation tool for planning and evaluating innovative education delivery and dissemination. The CERTAIN program provided an example for other continuous professional education projects.
Socio-Economic Productive Capacities and Energy Efficiency: Global Evidence by Income Level and Resource Dependence
Authors: Demiral Mehmet , Demiral Özge 
Published: August 2021

Abstract
This study tests the effects of productive capacities in socio-economic factors (human capital, transport, information-communication technology, institutions, private sector, and structural change) on energy efficiency in a sample of 125 countries. Energy efficiency is assessed by energy productivity (gross domestic product per unit of total primary energy supply) and energy intensity (total primary energy supply per capita). The world sample is divided into four income groups and an income-heterogeneous control group of non-renewable resource-dependent economies. The study utilizes cross-sectionally dependent and stationary panel data over the period 2000-2018. The analysis of variance shows that higher income groups monotonically have higher productive capacities and energy intensity. The regression results from appropriate fixed-effects and random-effects modeling reveal varied driver and barrier influences of the socio-economic factors on energy efficiency improvements (higher energy productivity and lower energy intensity). In some cases, predictors scale up both energy productivity and energy intensity indicating the issue of the rebound effect. Higher human capital capacity stimulates energy efficiency except for middle-income groups. Higher transport capacity reduces energy productivity, except for upper-middle-income economies, and tends to increase energy intensity for low-income and middle-income groups. The deployment of information-communication technologies is positively associated with energy productivity, except for low-income economies. Energy productivity performance of resource-dependent economies is improved by higher productive capacities in institutions and private sectors but impaired by structural change, whereas structural change drives energy efficiency in low-income economies. Additionally, the growth of gross national income per capita worsens energy efficiency for resource-dependent economies. Bidirectional feedback causalities are established between energy efficiency and its predictors in most cases. The heterogeneous findings are discussed for providing research and policy implications.
Assessment of Genetic Diversity Among Chinese High-Oleic Peanut Genotypes Using Miniature Inverted-Repeat Transposable Element Markers
Authors: Wang Chuan Tang , Song Guo Sheng , Wang Zhi Wei , Li Hong Ju , Han Hong Wei , Wang Xiu Zhen , Sun Xiu Shan 
Published: August 2021

Abstract
As compared with normal-oleic peanut, high-oleic peanut proved to be heart-healthier, and had prolonged shelf life and extended seed longevity. However, there have concerns about the genetic diversity of present-day high-oleic peanut cultivars, which relied heavily on high-oleic donors with F435 type FAD2 mutations. In the study, a total of 104 high-oleic peanut cultivars/lines/mutants from main breeding teams in China were used to assess their genetic diversity with AhMITE markers. Of all the 31 cultivars tested, those from CTW team had the highest genetic variability. Again, of all the 73 lines studied, those from CTW team ranked first in genetic diversity. As compared with cultivars from CTW and C&Y teams, greater genetic diversity was detected in new lines of both teams, indicating that recent breeding efforts had resulted in improved genetic diversity in high-oleic peanut.
On the Use of Self-Organizing Maps in Detecting Teleconnections. Part I: Spatial Aspects
Authors: Stryhal Jan , Beranová Romana , Huth Radan 
Published: August 2021

Abstract
Self-organizing maps (SOMs) represent a popular classification tool, output of which has been used to link typical synoptic-scale circulation patterns to large-scale teleconnections, or modes of low-frequency circulation variability. However, recently there have been attempts to interpret SOM output directly as a continuum of teleconnections. In the present paper, we provide a theoretical study dealing with how predefined idealized modes of variability project onto SOM arrays. Three orthogonal modes are defined and their various linear combinations used to generate datasets of known structure. Multiple variants of SOMs that differ in their initialization are generated for SOMs of various shapes and sizes. The results show that how a mode projects on a SOM array is sensitive not only to data structure, but also to various SOM parameters. The leading mode of variability projects rather strongly on SOMs if its explained variance is markedly higher than that of the second-order mode; the remaining modes project considerably more weakly, and all modes tend to blend when their explained variance is close to each other, which leads to underrepresentation of some phases of modes and/or combinations of modes among the SOM patterns. Furthermore, non-linear features appear in SOM arrays even if the underlying modes of variability are strictly linear. The findings point to limitations in the applicability of SOMs in the research of teleconnections.
Blood Transfusion Had No Influence on the 5-year Biochemical Recurrence After Robot-assisted Radical Prostatectomy: A Retrospective Study
Authors: Han Jiwon , Jeon Young-Tae , Ryu Jung-Hee , Oh Ah-Young , Kim Hwanik , Bae Yu Kyung , Koo Chang-Hoon 
Published: August 2021

Abstract
BackgroundAlthough red blood cells (RBC) transfusion is known to be significantly associated with biochemical recurrence in patients undergoing open prostatectomy, its influence on biochemical recurrence after robot-assisted laparoscopic radical prostatectomy remains unclear. Therefore, this study aimed to validate the effect of RBC transfusion on the 5-year biochemical recurrence in patients undergoing robot-assisted laparoscopic radical prostatectomy. MethodsThis study retrospectively analyzed the medical records of patients who underwent robot-assisted laparoscopic radical prostatectomy at single tertiary academic hospital between October 2007 and December 2014. Univariate and multivariate Cox proportional hazard regression analysis was performed to identify any potential variables associated with 5-year biochemical recurrence. ResultsA total of 1311 patients were included in the final analysis. Of these, 30 patients (2.3%) were transfused with RBC either during robot-assisted laparoscopic radical prostatectomy or during their hospital stay, which corresponded to 5-year biochemical recurrence of 15.7%. Multivariate Cox proportional hazard regression analysis showed that RBC transfusion had no influence on the 5-year biochemical recurrence. Variables including pathologic T stage (Hazard ratio [HR] 3.5, 95% confidence interval [CI] 2.4-5.1 p < 0.001), N stage (HR 2.3, 95% CI 1.5-3.7, p < 0.001), Gleason score (HR 2.4, 95% CI 1.8-3.2, p < 0.001), and surgical margin (HR 2.0, 95% CI 1.5-2.8, p < 0.001) were independently associated with the 5-year biochemical recurrence.ConclusionsRBC transfusion had no significant influence on the 5-year biochemical recurrence in patients undergoing robot-assisted laparoscopic radical prostatectomy.
Advantages and Disadvantages of Different Coupling Methods of Plasma Antennas
Authors: Hadaegh Mostafa , Mohajeri Farzad 
Published: August 2021

Abstract
One of the important challenges in plasma antennas, is the coupling of RF signal to the plasma column. RF signal coupling has a significant effect on antenna efficiency, antenna implementation cost, structure implementation complexity, antenna pattern shape, and final structure weight and volume. In this article, firstly the various methods of coupling were introduced. Then capacitive coupling, direct coupling and sleeve coupling were presented and their advantages and disadvantages were mentioned. As a sample, a plasma folded monopole antenna with sleeve coupling was fabricated and measured. By comparison of the different coupling methods and as a result, one can conclude that the sleeve coupling method is the most suitable method. This method has the least sensitivity to change the dimensions. It is also easy and cheap to implement. In this type of coupling, the efficiency of the Nesta antenna is suitable and the coupling structure adds small weight and volume to the antenna structure.