bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genomics and transcriptomics landscapes associated to changes in insulin sensitivity in response to endurance exercise training
Authors: Takeshita Louise Y. , Davidsen Peter K. , Herbert John M. , Antczak Philipp , Hesselink Matthijs K. C. , Schrauwen Patrick , Weisnagel S. John , Robbins Jeremy M. , Gerszten Robert E. , Ghosh Sujoy , Sarzynski Mark A. , Bouchard Claude , Falciani Francesco 
Published: December 2021

AbstractDespite good adherence to supervised endurance exercise training (EET), some individuals experience no or little improvement in peripheral insulin sensitivity. The genetic and molecular mechanisms underlying this phenomenon are currently not understood. By investigating genome-wide variants associated with baseline and exercise-induced changes (∆) in insulin sensitivity index (Si) in healthy volunteers, we have identified novel candidate genes whose mouse knockouts phenotypes were consistent with a causative effect on Si. An integrative analysis of functional genomic and transcriptomic profiles suggests genetic variants have an aggregate effect on baseline Si and ∆Si, focused around cholinergic signalling, including downstream calcium and chemokine signalling. The identification of calcium regulated MEF2A transcription factor as the most statistically significant candidate driving the transcriptional signature associated to ∆Si further strengthens the relevance of calcium signalling in EET mediated Si response.
Self-selective ferroelectric memory realized with semimetalic graphene channel
Authors: Jung Sungchul , Park Jinyoung , Kim Junhyung , Song Wonho , Jo Jaehyeong , Park Hyunjae , Kong Myong , Kang Seokhyeong , Sheeraz Muhammad , Kim Ill Won , Kim Tae Heon , Park Kibog 
Published: December 2021

AbstractA new concept of read-out method for ferroelectric random-access memory (FeRAM) using a graphene layer as the channel material of bottom-gated field effect transistor structure is demonstrated experimentally. The transconductance of the graphene channel is found to change its sign depending on the direction of spontaneous polarization (SP) in the underlying ferroelectric layer. This indicates that the memory state of FeRAM, specified by the SP direction of the ferroelectric layer, can be sensed unambiguously with transconductance measurements. With the proposed read-out method, it is possible to construct an array of ferroelectric memory cells in the form of a cross-point structure where the transconductance of a crossing cell can be measured selectively without any additional selector. This type of FeRAM can be a plausible solution for fabricating high speed, ultra-low power, long lifetime, and high density 3D stackable non-volatile memory.
Exceptional points in oligomer chains
Authors: Downing Charles Andrew , Saroka Vasil Arkadievich 
Published: December 2021

AbstractSymmetry underpins our understanding of physical law. Open systems, those in contact with their environment, can provide a platform to explore parity-time symmetry. While classical parity-time symmetric systems have received a lot of attention, especially because of the associated advances in the generation and control of light, there is much more to be discovered about their quantum counterparts. Here we provide a quantum theory which describes the non-Hermitian physics of chains of coupled modes, which has applications across optics and photonics. We elucidate the origin of the exceptional points which govern the parity-time symmetry, survey their signatures in quantum transport, study their influence for correlations, and account for long-range interactions. We also find how the locations of the exceptional points evolve as a function of the chain length and chain parity, capturing how an arbitrary oligomer chain transitions from its unbroken to broken symmetric phase. Our general results provide perspectives for the experimental detection of parity-time symmetric phases in one-dimensional arrays of quantum objects, with consequences for light transport and its degree of coherence.
Configurable pixelated skyrmions on nanoscale magnetic grids
Authors: Zhang Xichao , Xia Jing , Shirai Keiichiro , Fujiwara Hiroshi , Tretiakov Oleg A. , Ezawa Motohiko , Zhou Yan , Liu Xiaoxi 
Published: December 2021

AbstractTopological spin textures can serve as non-volatile information carriers. Here we study the current-induced dynamics of an isolated magnetic skyrmion on a nanoscale square-grid pinning pattern formed by orthogonal defect lines with reduced magnetic anisotropy. The skyrmion on the square grid can be pixelated with a quantized size of the grid. We demonstrate that the position, size, and shape of skyrmion on the square grid are electrically configurable. The skyrmion center is quantized to be on the grid and the skyrmion may show a hopping motion instead of a continuous motion. We find that the skyrmion Hall effect can be perfectly prohibited due to the pinning effect of the grid. The pixelated skyrmion can be harnessed to build future programmable racetrack memory, multistate memory, and logic computing device. Our results will be a basis for digital information storage and computation based on pixelated topological spin textures on artificial pinning patterns.
Quantitative analysis of non-equilibrium systems from short-time experimental data
Authors: Manikandan Sreekanth K. , Ghosh Subhrokoli , Kundu Avijit , Das Biswajit , Agrawal Vipin , Mitra Dhrubaditya , Banerjee Ayan , Krishnamurthy Supriya 
Published: December 2021

AbstractEstimating entropy production directly from experimental trajectories is of great current interest but often requires a large amount of data or knowledge of the underlying dynamics. In this paper, we propose a minimal strategy using the short-time Thermodynamic Uncertainty Relation (TUR) by means of which we can simultaneously and quantitatively infer the thermodynamic force field acting on the system and the (potentially exact) rate of entropy production from experimental short-time trajectory data. We benchmark this scheme first for an experimental study of a colloidal particle system where exact analytical results are known, prior to studying the case of a colloidal particle in a hydrodynamical flow field, where neither analytical nor numerical results are available. In the latter case, we build an effective model of the system based on our results. In both cases, we also demonstrate that our results match with those obtained from another recently introduced scheme.
Ag(i)-Promoted homo-dimerization of 2-(alk-2-yn-1-onyl)-1-alkynylbenzenes via a [4 + 2] cycloaddition of benzopyrylium ions: access to structurally unique naphthalenes
Authors: Baire Beeraiah , Santhi Jampani 
Published: December 2021

Discovery and development of a Ag(i)-promoted, homodimerization of benzopyrylium ions (generated from 2-(alk-2-yn-1-onyl)-1-alkynylbenzenes) via a [4 + 2] cycloaddition, for the synthesis of naphthalenes is reported.
Lärm und Herz-Kreislauf-Erkrankungen
Authors: Hahad Omar , Röösli Martin , Daiber Andreas , Münzel Thomas 
Published: December 2021

ZusammenfassungUmgebungslärm stellt einen bedeutsamen umweltbezogenen Risikofaktor für die öffentliche Gesundheit dar. Die Europäische Umweltagentur gibt an, dass mindestens 20% der europäischen Bevölkerung schädlichen Tag-Abend-Nacht-Lärmpegeln von 55 Dezibel (dB) ausgesetzt sind, wobei die Weltgesundheitsorganisation zum Schutz der Bevölkerung, abhängig von der Lärmquelle, bis zu 10 dB tiefere Grenzwerte empfiehlt. Chronischer Lärm kann mit alltäglichen Aktivitäten und dem Schlaf interferieren und mentale sowie physiologische Stressreaktionen auslösen, die langfristig das Risiko für Herz-Kreislauf-Erkrankungen erhöhen können. Daher sind zwingend präventive Maßnahmen an der Quelle inklusive lärmreduzierender bautechnischer Veränderungen notwendig, um die Einhaltung von Lärmgrenzwerten zu gewährleisten und die Bevölkerung vor den negativen gesundheitlichen Auswirkungen des Lärms zu schützen.
Oral Hygiene Practice among 18-year-old Norwegian Adolescents Using Health Belief Model: A Cross-Sectional Study
Authors: Nasir Elwalid Fadul , Vu Johnny 
Published: December 2021

AbstractObjectives The aim was to compare oral hygiene practice (brushing/flossing) among 18 years old from two regions, Hordaland County, Norway, and possible perceptional correlates using the Health Belief Model.Materials and Methods The participants from six municipalities from the south district with high prevalence of dental caries to six municipalities from the rest of Hordaland county, with low prevalence of dental caries (control), using a web-based questionnaire. Statistical analyses: the Mann–Whitney U test was used and the t-test for independent samples. Bivariate and logistic regression analyses to examine associations.Results A total of 416 people participated. The south district’s participants had lesser percentage brushing twice a day and flossing at least once a day, they significantly visited lesser the dental service, perceived more susceptibility to dental caries, and lower benefits of brushing/flossing compared with the controls. Girls (odds ratio [OR]: 0.34) who perceived higher severity of dental caries (OR: 1.86), higher self-identity (OR: 2.14), and lesser barriers to brushing (OR: 0.14) had higher odds to brushing twice a day compared with their counterparts. Girls (OR: 0.34) who perceived higher severity of dental caries (OR: 2.34), higher benefits (OR = 2.8), and lesser barriers to flossing (OR = 0.23) had higher odds to flossing at least once a day compared with their counterparts.Conclusion South district’s participants significantly had some of risk factors to the recommended brushing/flossing practice compared with the control and these might help in explaining the difference in oral hygiene practice.
Role of Advanced MRI Techniques in the Quantitative Assessment of Liver Fat—A Multimodality-Based Comparative Study of Diagnostic Performance in a Tertiary Care Institute
Authors: Patil Santosh B. , Cannane Seetharaman , Poyyamoli Santhosh , Anand Rinoy R. , Kasi Venkatesh 
Published: December 2021

Abstract
Objective To evaluate the accuracy of noninvasive imaging methods including gray-scale ultrasound, ultrasound shear wave elastography, unenhanced computed tomography (CT), and proton density fat fraction (PDFF) on magnetic resonance imaging (MRI) using three-dimensional (3D) multiecho multipoint chemical shift–encoded spoiled gradient echo (q-DIXON) sequence in the quantification of hepatic steatosis, with proton MR spectroscopy (H1-MRS) as the reference standard in Indian population.
Methods Our study included 100 consecutive adult patients referred to the department of radiology in our hospital for imaging of liver. Fat content of liver was recorded using MRI (H1-MRS and q-DIXON), unenhanced CT (average liver attenuation [ALI] and liver attenuation index [LAI]) and ultrasonography (USG) (gray-scale grading and shear wave elastography [SWE]). Data were analyzed by linear regression and Bland–Altman analysis for each technique compared with H1-MRS. The diagnostic performances of all the methods were compared using DeLong test, for detection of mild and moderate-to-severe hepatic steatosis, separately.
Results MRI q-DIXON PDFF showed excellent correlation (r = 0.917, r2 = 0.840) and strong agreement (1.48 ±3.01) with H1-MRS-derived PDFF measurements. Unenhanced CT-based methods showed moderate correlation with modest agreement (r = −0.826, r2 = 0.681, −40.18 ± 16.05 for ALI and r = −0.858, r2 = 0.735, 13.4 ± 15.3 for LAI) whereas USG gray-scale assessment showed low correlation (weighted Kappa value 0.366) with H1-MRS PDFF. No correlation was found between USG-SWE results and PDFF measured with H1-MRS. Comparison of areas under curve (AUCs) using DeLong test revealed that MRI q-DIXON method performed the best for diagnosis of hepatic steatosis compared with rest. For moderate to severe steatosis, MRI q-DIXON and unenhanced CT-based methods had comparable diagnostic performance with AUCs not showing statistically significant differences.
Conclusion MRI q-DIXON shows strongest correlation with MRS and should be preferred for estimation of hepatic fat, especially when MRS is not available. Unenhanced CT shows limited diagnostic performance in detecting mild steatosis; however, it certainly has a role in diagnosing moderate-to-severe hepatic steatosis, such as evaluating donor candidates for living donor liver transplantation. USG, using both the traditional four-grade visual assessment and elastography in the present form, appears to have limited role in liver fat quantification.
Low Efficacy of Medication Shortage Clinical Decision Support Alerts
Authors: Benson Nicole M. , Belisle Caryn , Bates David W. , Salmasian Hojjat 
Published: December 2021

Abstract
Objective We examined clinical decision support (CDS) alerts designed specifically for medication shortages to characterize and assess provider behavior in response to these short-term clinical situations.
Materials and Methods We conducted a retrospective analysis of the usage of medication shortage alerts (MSAs) that included at least one alternative medication suggestion and were active for 60 or more days during the 2-year study period, January 1, 2018 to December 31, 2019, in a large health care system. We characterized ordering provider behavior in response to inpatient MSAs. We then developed a linear regression model to predict provider response to alerts using the characteristics of the ordering provider and alert frequency groupings.
Results During the study period, there were 67 MSAs in use that focused on 42 distinct medications in shortage. The MSAs suggested an average of 3.9 alternative medications. Adjusting for the different alerts, fellows (p = 0.004), residents (p = 0.03), and physician assistants (p = 0.02) were less likely to accept alerts on average compared with attending physicians. Further, female ordering clinicians (p < 0.001) were more likely to accept alerts on average compared with male ordering clinicians.
Conclusion Our findings demonstrate that providers tended to reject MSAs, even those who were sometimes flexible about their responses. The low overall acceptance rate supports the theory that alerts appearing at the time of order entry may have limited value, as they may be presented too late in the decision-making process. Though MSAs are designed to be attention-grabbing and higher impact than traditional CDS, our findings suggest that providers rarely change their clinical decisions when presented with these alerts.
Periodised Carbohydrate Intake Does Not Affect Substrate Oxidation but May Contribute to Endurance Capacity
Authors: Salokannel Meri M. , Hakulinen Oona‐Mari , Ahtiainen Juha P. 
Published: December 2021

ABSTRACTThe aim of this study was to investigate whether periodising carbohydrate intake around specific training sessions will enhance endurance training adaptations.Seventeen healthy recreationally endurance‐trained males (n = 5) and females (n = 12) (27.5 ± 5.4 years) participated in a four‐week training intervention. Participants were divided into two groups: FASTED (stayed fasted between evening high‐intensity interval training session and low‐intensity training session in the following morning) and FED (no restriction in food intake). Pre‐ and post‐testing included peak oxygen uptake (VO2peak), anaerobic capacity, and 60 min submaximal running tests. Fasted venous blood samples were drawn for the determination of triglyceride and glucose concentrations.VO2peak increased in both FASTED (4.4 ± 3.0%, p = 0.001) and FED (4.6 ± 4.2%, p = 0.017), whereas maximal running velocity increased only in the FASTED (3.5 ± 2.7%, p = 0.002). Lactate concentrations in the anaerobic test after intervention were greater in FASTED than FED (p = 0.025‐0.041). Running time in the anaerobic test was improved in FASTED (from 64.1 ± 15.6–86.3 ± 23.2 s, p < 0.001) but not in FED (from 56.4 ± 15.2–66.9 ± 21.3 s, p = 0.099). Substrate oxidation did not change after intervention in either of the groups (p = 0.052–0.597). Heart rate was lower in the submaximal running test in FASTED (p < 0.001) but not in FED (p = 0.097).Training with periodised carbohydrate availability does not have any effect on substrate oxidation. However, it seems to enhance the capacity to perform high‐intensity exercise.
Signatures of intrinsic decoherence and weak measurement on quantum correlations
Authors: Bhuvaneswari S , Muthuganesan R , Radha R 
Published: December 2021

Abstract
In this article, we consider a pair of spin-1/2 particles with squeezing coupling serving as the physical carrier of quantum information. We then examine the dynamics of quantum correlation quantified by the entanglement and measurement-induced nonlocality (MIN) under the intrinsic decoherence. The impact of intrinsic decoherence on the dynamical behaviors of quantum correlations is investigated. We show that the MIN quantities are more robust, while intrinsic decoherence cause sudden death in entanglement. Besides, we highlight the role of spin squeezing coupling and external magnetic field on quantum correlation measures. Finally, we investigate the impact of weak measurement on MIN.
2nd International Conference on Computational Intelligence and Energy Advancements (ICCIEA-2021), September 11-12, 2021 Virtual Format
Authors: Gupta Nishu , Kumar Parvesh , Pali H. S. 
Published: December 2021

International Conference on Computational Intelligence and Energy Advancements (ICCIEA-2021) is a prestigious event organized with a motivation to provide an excellent platform for the academicians, researchers, engineers, industrial participants and budding students around the world to share their research findings with the global experts. The conference aimed to provide researchers and attendees with prospects for global collaboration and networking among universities and corporate organizations for promoting research. ICCIEA-2021 was conducted in virtual format owing to the pandemic situation during 11th to 12th September 2021. It involved all classes of academia having research orientation.
The conference was organized jointly by departments of ECE and ME, Vaagdevi College of Engineering and King Abdulaziz University, Rabigh, Saudi Arabia. As it was an event conducted in cyber form, the presentations were delivered using an online platform. Five different and parallel technical sessions were scheduled based upon the tracks of the articles and a Best Paper was awarded in each session. A total of 38 articles were selected for presentation after double blind peer review process. This proceeding issue compiles oral presentations that were presented by the authors and rigorously reviewed by a special committee designated by the editor team of the conference.
The organizing and editorial committee of the ICCIEA-2021 hopes you enjoy reading the articles published in this volume of the JPCS. Besides, we wish to thank all the authors and participants for providing their valuable contributions for this proceeding as well as the reviewers for their constructive recommendations and criticism aiding to improve the presented articles. We are confident that this issue will serve as a reference for computational intelligence, industrial automation, energy advancements and sustainable technologies in the world of scientific research, engineering and technology.
List of Organizing Committee, Steering Committee, Technical Program Committee, Industry Experts Committee, Editorial Committee, Invited Speakers, Organizing Institutions, Academic Partner are available in this pdf.
Design of Quad feed end-fire microstrip patch antenna for Airborne Systems
Authors: Gnanalakshmi V , Raaj Rahul , Suresh Kumar V 
Published: December 2021

Abstract
To design a quad feed end-fire microstrip patch antenna for airborne systems. Basically these type of antennas are most helpful for avoiding mid-air collisions between aircraft. The microstrip patch antenna is very small in size and it is less in weight. Due to small size and less weight, it offers an easy design and fabrication process. The microstrip patch antenna has radiating patch on one side and ground on the other side. They operate at microwave frequencies. The low profile structure of microstrip antenna offers its wide use in wireless communication. They are used as communication antenna on missiles. Traffic alert and Collision Avoidance System (TCAS) is an airborne system which is utilized to provide the service as last defense equipment for avoiding mid-air collisions between the aircraft. 1.03 GHz and 1.09 GHz are the transmitting and receiving frequencies of the existing TCAS antenna respectively. In airborne systems, low aerodynamic drag is required. FR4 epoxy is chosen as the substrate material whose dielectric constant is 4.4. 1.06GHz is chosen as the design frequency, since it is centre frequency between 1.03GHz and 1.09GHz. Microstrip patch antenna always radiates in the broadside direction which is along elevation plane. Due to metallic cap, microstrip patch antenna can also radiate in the end fire radiation which is along the azimuth plane. The ground plane must have very large dimensions than the patch. This microstrip patch antenna working at UHF (Ultra High Frequency) band is designed and their parameters like gain, directivity, return loss, VSWR (Voltage Standing Wave Ratio) and radiation pattern have been analyzed and simulated using ANSYS HFSS (High Frequency Structure Stimulator).
Performance Analysis of Linear Precoding in Downlink Based on Polynomial Expansion on Massive MIMO Systems
Authors: Thurpati Sammaiah , Mudavath Mahesh , Muthuchidambaranathan P. 
Published: December 2021

Abstract
The performance of linear precoding schemes in downlink Massive MIMO systems is dealt with in this paper. Linear precoding schemes are incorporated with zero-forcing (ZF) and maximum ratio transmission (MRT), truncated polynomial expansion (TPE), regularized zero force (RZF) in Downlink massive MIMO systems. Massive MIMO downlink output is evaluated with linear precoding included. This paper expresses the performance of achievable sum-rate linear precoding with variable signal-to-noise (SNR) ratio and achievable sum rate and several transmitter-receiver antennas, such as imperfect CSI, less complex processing, and inter-user interference. The transmitter has complete state information on the channel. The information narrates how a signal propagates to the receiver from the transmitter and reflects, for example, the cumulative effect of distance scattering, fading, and power decay. They show that the performance analysis of two linear precoding techniques, i.e., Maximum Ratio Transmission (MRT) and Zero Forcing (ZF) for downlink mMIMO output network over a perfect chain. The results show the improved ZF precoding achievable sum rate compared to the MRT precoding schemes and compared the average achievable rate RZF and TPE.
A smart Agriculture Irrigation System using sensor array based IOT
Authors: Murali Kola , Sridhar B. 
Published: December 2021

Abstract
The role of Agriculture is important to build a nation, since more than 58% of the population in our country is dependent on agriculture that means half of the population is investing in agriculture. However, many farmers are unfamiliar with intelligent irrigation systems designed to improve the water used for their crops. The proposed system is to precisely monitor the distribution of the water to crops. This IOT based system has a distributed wireless network of soil moisture sensors to monitor soil moisture. Other sensors such as temperature, humidity, rain, IR, LDR, foot. The gateway device also processes the detector’s information and transmits the data to the farmer. An algorithm was developed using threshold values for soil moisture and nutrients, and these values were programmed into a node com-based gateway to control water for irrigation. Complete sensor data is sent to the free cloud using NODEMCU and displayed on websites and apps. This proposed work presents extensive research on irrigation systems in smart agriculture.