bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utilizing Telemedicine for Delivery of Postoperative Care Following Minimally Invasive Gynecologic Surgery
Authors: Radtke Steven , Umeh Randle , Chavez Martha , Curiel Zuleika , Mendez Karla 
Published: August 2021

Objectives:
Determine if patient satisfaction is greater after delivering postoperative care via telemedicine following minimally invasive gynecologic surgery.

Materials and Methods:
University-based outpatient clinic; Randomized controlled trial (Canadian Task Force classification I). Females between 18 and 60 years of age scheduled to undergo laparoscopic hysterectomy or laparoscopic excision of endometriosis were invited to participate. Eligible patients were randomized to receive postoperative care either through a traditional office visit or via telemedicine. PSQ-18 satisfaction surveys were performed by phone after the visit.

Results:
Forty-one patients were analyzed out of which 25 were in the office group and 16 in the telemedicine group. Groups were homogenous to age (41.4 vs. 43.3 p. 48), body mass index (31.9 vs. 30.6 P = 0.52), distance in miles from home (12.7 vs. 12.4 P = 0.92), and parity (P = 0.51). PSQ-18 questionnaire was scored and each category was compared between the office and telemedicine groups. When comparing medians (interquartile range), the general satisfaction and time spent with doctor categories were significantly higher in the telemedicine group (4.0 [4.0, 4.5] vs. 4.5 [4.5, 5.0] P = 0.05), (4.0 [4.0, 4.5] vs. 4.5 [4.0, 5.0] P = 0.05). The remainder of the categories analyzed were not different between groups Technical Quality (4.0 [3.8, 4.5] vs. 4.5 [3.9, 5.0] P = 0.13), Interpersonal Manner (4.0 [4.0, 4.5] vs. 4.5 [4.0, 5.0] P = 0.34), Communication (4.5 [4.0, 4.5] vs. 4.5 [4.3, 5.0] P = 0.21), Accessibility and Convenience (4.0 [3.5, 4.5] v 4.0 [3.6, 4.5] P = 0.84). A chart review was performed, examining the first 30 days after surgery. One (4%) patient in the office group went to the ER after postoperative visit, and 0 in the telemedicine group (P = 0.42).

Conclusion:
Postoperative care via telemedicine after gynecologic surgery results in higher patient satisfaction.
Assessment of Tubal Patency with Selective Chromopertubation at Office Hysteroscopy versus Modified Minilaparoscopy in Infertile Women
Authors: Roy Kallol Kumar , Gajapathy Sheela Rangamani , Rai Rakhi , Zangmo Rinchen , Das Anamika , Singhal Seema 
Published: August 2021

Objectives:
Tubal factor is the leading cause of female infertility. Diagnostic hysterolaparoscopy with chromopertubation plays a pivotal role in its evaluation. Office hysteroscopy (OH) has gained popularity as the outpatient procedure for diagnostic purposes. OH being a less invasive approach, the current study was undertaken to compare the accuracy of assessment of tubal patency with chromopertubation at OH with modified minilaparoscopy in infertile patients.

Materials and Methods:
The present study was a pilot study conducted from March 2017 to August 2018. Eighty patients were recruited. OH was done without anesthesia. Diluted methylene blue dye was injected. The eddy current of blue dye, “Visualizable flow” at ostium, and disappearance of blue dye from the uterine cavity through ostium was documented as evidence of patent tubal ostium. In case of tubal occlusion, uterine cavity became blue due to backflow of dye. After OH, minilaparoscopy with chromopertubation was performed under general anesthesia. Both tubes were assessed separately for tubal patency.

Results:
All patients underwent OH followed by minilaparoscopy in the same sitting. OH was 87.5% sensitive with positive predictive value of 95.2%. Compared to minilaparoscopy, OH is 85.6% accurate in predicting tubal patency. The area under receiver operating curve was 0.96 (SE is 0.15 with 95% confidence interval of 0.93–0.99, P < 0.001). It implies that, OH should correctly identify all laparoscopic cases with probability of 0.96.

Conclusion:
OH chromopertubation can be used as an alternative to laparoscopy for assessing tubal patency with added advantages of lack of requirement of anesthesia, minimal cost, and better patient acceptance. Moreover, the procedure is less time-consuming and less invasive with high sensitivity and moderate specificity.
Camptothecin enhances 131I-rituximab-induced G1-arrest and apoptosis in Burkitt lymphoma cells
Authors: Kumar Chandan , Sharma Rohit , Repaka Krishna Mohan , Pareri Aanchal Udaynath , Dash Ashutosh 
Published: August 2021

Background:
Rituximab is a chimeric monoclonal antibody against CD20. It is an established immunotherapeutic agent for non-Hodgkin's lymphoma. Even though rituximab has been used in clinics for decades, only 50% of the patients respond to rituximab therapy. To enhance the in vitro effect of rituximab, it was labeled with Iodine-131 (131I) and combined effect of 131I-rituximab and camptothecin (CPT) was studied on a tumor cell line expressing CD20.

Objective:
The aim is to study the magnitude of cell killing and the underlying mechanism responsible for enhancing in vitro therapeutic efficacy.

Materials and Methods:
Rituximab was labeled with 131I by the iodogen method. Raji cells were pretreated with CPT (250 nM) for an hour followed by 131I-rituximab (0.37 and 3.7 MBq) and incubated for 24 h in a humidified atmosphere of CO2 incubator at 37°C. Subsequently, Raji cells were harvested and thoroughly washed to carry out studies of cellular toxicity, apoptosis, cell cycle, and mitogen-activated protein kinase (MAPK) pathways.

Results:
Maximal inhibition of cell proliferation and enhancement of apoptotic cell death was observed in the cells treated with the combination of CPT and 131I-rituximab, compared to controls of CPT-treated and 131I-rituximab-treated cells. Raji cells undergo G1 arrest after 131I-rituximab treatment, which leads to apoptosis and was confirmed by the downregulation of bclxl protein. Expression of p38 was decreased while an increase in phosphorylation of p38 was observed in the combination treatment of CPT and 131I-rituximab.

Conclusions:
It was concluded from the findings that CPT enhanced 131I-rituximab-induced apoptosis, G1 cell cycle arrest and p38 MAPK phosphorylation in Raji cells.
Hepatocyte paraffin-1, CD10, and CD34 immunostaining as a diagnostic aid in cytologic diagnosis of hepatic cancer
Authors: Agarwal Anushree , Handa Uma , Kundu Reetu , Sachdev Atul , Kochhar Suman 
Published: August 2021

Background:
Cytomorphological distinction between hepatocellular carcinoma and metastatic tumors to the liver may be difficult, especially when these have poor differentiation. The present study was done to assess the diagnostic utility of hepatocyte paraffin-1 (HepPar-1), CD10, and CD34 in differentiating hepatocellular carcinoma from metastatic carcinoma.

Materials and Methods:
Ultrasound-guided fine-needle aspiration was performed on 50 patients with space-occupying lesions of liver suspicious for malignancy on clinical/radiologic findings. The cytological assessment was done on smears stained with May–Grünwald–Giemsa and hematoxylin and eosin. Cell blocks were prepared, and immunostaining for HepPar-1, CD10, and CD34 was done.

Results:
In these 50 patients, hepatocellular carcinoma was diagnosed in 7 and metastatic tumors in 43 cases. The sensitivity of smears in diagnosing hepatocellular carcinoma was 100% and the specificity was 95.3%, while the sensitivity and specificity of cell block were 100%. A canalicular pattern of CD10 immunoreactivity had a 100% positive predictive value for diagnosing hepatocellular carcinoma. CD10 had a sensitivity of 57.1% and 41.9% in identification of HCC and metastatic tumors, respectively. For the diagnosis of hepatocellular carcinoma, the sensitivity of CD34 was 85.7% and the specificity of sinusoidal pattern of immunoreactivity was 100%. The sensitivity and specificity of granular cytoplasmic staining pattern of HepPar-1 were 100% in hepatocellular carcinoma.

Conclusions:
The staining patterns of HepPar-1, CD10, and CD34 are highly specific in distinguishing hepatocellular carcinoma from metastasis. These three immunomarkers should be included in the immunocytochemical panel for differentiating hepatocellular carcinoma from metastatic carcinoma to the liver.
Effects of fluoridated tooth paste on medically erosive enamel in bonded primary teeth during maxillary arch expansion in cleft palate patient
Authors: Qasim Aisha Akram , Alani Baraa W. , Al Qassar Sarmad S. Salih 
Published: August 2021

AIMS:
This study searched the effects of fluoridated toothpaste on the enamel surface of deciduous molars eroded by different pediatric liquid medicaments which were encircled by orthodontic bands by gravimetric analysis method.

MATERIALS AND METHODS:
A suitable orthodontic band was used to band each of the 110 non-carious exfoliated deciduous molars, and stored in artificial saliva. These teeth were divided randomly into fluoridated and non-fluoridated groups (50 teeth each), and 10 teeth were used as negative controls. The enamel surface of the fluoridated group was swabbed with fluoridated toothpaste for 5 minutes twice daily. Each group was subdivided into five clusters of 10 teeth each according to the type of medication used which included paracetamol, Adol, amoxicillin, Medazole (ME), and Viton (VI) according to a specific immersion cycle. The erosion induced in the enamel for all the teeth was evaluated by gravimetric analysis for different intervals.

RESULTS:
The results showed that the weight loss increased with increasing exposure to liquid medication for all groups, but this increase was smaller in the fluoridated group. The highest mean weight loss after 28 days was in VI, and the lowest was in ME (0.145 [0.005] mg; 0.08 [0.008] mg), respectively.

CONCLUSION:
The fluoridated toothpaste significantly reduced medically eroded enamel by oral medical syrups. The gravimetric method is valid for the detection of erosion on banded deciduous molars.
Therapeutic use of alpha lipoic acid in burning mouth syndrome
Authors: Roy Shubhabrata , Raj Deepa , Bhattacharyya Jayanta , Das Samiran , Goel Preeti 
Published: August 2021

Introduction:
Primary burning mouth syndrome (BMS) is a chronic pain disorder of the oral cavity without any apparent local or systemic etiologic factor. There is no specific therapy for primary BMS and treatment is basically supportive or symptomatic. There are many pharmacological and nonpharmacological approaches reported by different studies to alleviate pain in primary BMS. Alpha lipoic acid (ALA) has also been used as a therapeutic agent in BMS by many clinicians and researchers.

Aims:
The aim of this review and meta-analysis was to evaluate the double-blinded placebo controlled randomized clinical trials of ALA to determine its efficacy and potential as therapeutic agent in primary BMS. Six studies were selected for the systematic review after a thorough manual and electronic searching of the databases.

Methods:
Five out of the 6 selected studies were used for quantitative data synthesis.

Results and discussion:
The ALA therapy for 2 months provided symptomatic relief to more people in the study groups than in the placebo groups (risk ratio 2.34, 95% confidence interval [CI]: 1.71–3.19). The mean visual analog scale (VAS) scores of the test groups improved (decreased) after 2 months of ALA therapy (standardised mean difference [SMD] 0.72, 95% CI 0.20–1.24). When compared with placebo therapy, mean VAS scores improved (decreased) more with placebo than with ALA after 2 months of treatment (SMD −0.23, 95% CI: −0.70–0.24). The positive responders in the ALA groups presented less incidence of deterioration than the positive responders in placebo groups during the follow-up period.

Conclusion:
It was concluded from this meta-analysis that ALA could be used as a potential therapeutic agent in primary BMS. It should be administered in proper therapeutic doses and for sufficient time to elicit positive outcome. ALA can be used for a long time without any severe side effect and very few recipients complained about worsening of the situation. It certainly improves pain symptoms in a considerable number of patients when compared with placebo therapy.
CONCEPÇÕES E ABORDAGENS DO ENSINO DA GEOGRAFIA:
Authors: Soares Lucélia dos Reis Santos , Lobato Kelson Lucien Rodrigues 
Published: August 2021

Este artigo tem o objetivo de apresentar a importância do ensino de Geografia nos anos inicias da educação básica e suas principais abordagens, tradicional e crítica para o processo de ensino-aprendizagem. Tal processo com base nas abordagens teórico-metodológicas da ciência geográfica visa contribuir na formação de sujeitos críticos, analíticos e interativos, a partir da realidade social a qual estão inseridos. O estudo primou em realizar uma pesquisa bibliográfica, apresentando as diferentes concepções da Geografia para o ensino da disciplina nos anos iniciais. A pesquisa deteve-se também em compreender de que forma o livro didático pode contribuir na formação do sujeito com base nos pressupostos teórico-metodológicos que este recurso apresenta. Por fim, as reflexões apontam que existe uma intervenção pedagógica dos educadores ao ministrar aulas da disciplina nos anos iniciais, com base na abordagem geográfica presente no livro didático adotado. Nesse processo de formação inicial do conhecimento, o letramento geográfico e a alfabetização cartográfica auxiliam no melhor entendimento dos conteúdos ministrados, buscando romper com uma disciplina tradicional e enfadonha ao surgir a Geografia Crítica como nova proposta metodológica de ensino. Esta apresenta-se com maior potencial integrador diante das dimensões da realidade do cotidiano do aluno.
Palavras-chave
Ensino, Alfabetização cartográfica, Geografia.

CONCEPTIONS AND APPROACHES WITH REGARD TO TEACHING GEOGRAPHY: the importance of Cartographic knowledge in the elementary school
Abstract
This article aims to present the importance of geography teaching in the initial years and the main traditional and critical approaches to the teaching-learning process. This process is based on the theoretical-methodological approaches of the science of geography science and aims to contribute to the formation of critical, analytical and interactive subjects, from the social reality into which they are inserted. The study focused on a bibliographical research, presenting the different conceptions of geography for the teaching of the discipline in the first years of the elementary school. The research also focused on understanding how the textbook can contribute to the formation of the subject based on the theoretical-methodological assumptions that this resource presents. Finally, the reflections indicate that there is a pedagogical intervention of teachers and educators in teaching the discipline in the initial years and develop the classes based on the geographical approach present in the textbook adopted. In this process of initial knowledge formation, geographic literacy and cartographic literacy aid in the best understanding of the contents taught. Seeking to break with a traditional and boring discipline, the emergence of Critical Geography presents a new methodological approach to teaching. This offers greater integrative potential in the face of the dimensions of student´s daily realities.
Keywords
Teaching, Cartographic literacy, Geography.
A Selective Bilingual Advantage in High School Students
Authors: Khotemlyansky Laura , Berge Jill 
Published: August 2021

The present study investigates the impacts of bilingualism on academic performance among high school students by using cognitive assessment scores as proxies for GPAs. As seminal works, finding a constant bilingual advantage (BA), are being increasingly disproved in favor a selective BA, task demand in working memory (WM) was introduced to examine this. A mixed method was used. Participants completed a self-assessment survey, rating their academic performance and beliefs regarding the bilingual advantage hypothesis. Then, the flanker and modified flanker tasks tested participants’ WM. Using measurements of the means, medians and p-test, it was discovered that bilingual students only outperformed monolinguals on the low demand regular flanker task while equally on all other tasks, not in accordance with the Executive Control Theory (ECT) commonly supported in recent works. Additionally, the survey revealed that both monolingual and bilingual students recognize the positive impacts of language on cognition, but not the application of cognition to increased school performance. By bringing awareness to this relationship, this could encourage more students to study a foreign language in high school, bridging the cognitive-linguistic gap.
Mental Health Ramifications of Social Distancing in the Elderly
Authors: Larson Thomas , Sierra Janette 
Published: August 2021

There were many unknown factors that arose from the spread of COVID-19 worldwide. Many researchers began to conduct research on questions surrounding this pandemic. One such question is how the COVID-19 pandemic affects people’s mental states. This is, of course, far too broad of a question to properly research, but this study narrows down that question to discover the effect of the pandemic on the elderly’s self-perceived loneliness and depression.
This question was researched using a survey design that collected quantitative data, which was then interpreted with qualitative statistics to better understand the meaning of the results. This survey was conducted in a nursing home in February of 2021. This nursing home is in Miami and a total of 40 participants were used in the data collection, though two were later omitted due to incomplete responses. In keeping with the common demographic of Miami, many of the participants were Spanish speaking, and the questionnaires and consent forms were translated and offered in both English and Spanish.
Of the 40 participants that responded, all used the Spanish translation forms. Because of how recent this pandemic is and the length of time it takes for professional researchers to report findings accurately, there are few resources. The data that does exist is from earlier phases in the COVID-19 pandemic, and thus rather indefinite.
Thermal legacy of a large paleolake in Taylor Valley, East Antarctica, as evidenced by an airborne electromagnetic survey
Authors: Myers Krista F. , Doran Peter T. , Tulaczyk Slawek M. , Foley Neil T. , Bording Thue S. , Auken Esben , Dugan Hilary A. , Mikucki Jill A. , Foged Nikolaj , Grombacher Denys , Virginia Ross A. 
Published: August 2021

Abstract. Previous studies of the lakes of the McMurdo Dry Valleys have
attempted to constrain lake level history, and results suggest the lakes
have undergone hundreds of meters of lake level change within the last
20 000 years. Past studies have utilized the interpretation of geologic
deposits, lake chemistry, and ice sheet history to deduce lake level
history; however a substantial amount of disagreement remains between the
findings, indicating a need for further investigation using new techniques.
This study utilizes a regional airborne resistivity survey to provide novel
insight into the paleohydrology of the region. Mean resistivity maps
revealed an extensive brine beneath the Lake Fryxell basin, which is
interpreted as a legacy groundwater signal from higher lake levels in the
past. Resistivity data suggest that active permafrost formation has been
ongoing since the onset of lake drainage and that as recently as 1500–4000 years BP, lake levels were over 60 m higher than present. This coincides
with a warmer-than-modern paleoclimate throughout the Holocene inferred by
the nearby Taylor Dome ice core record. Our results indicate Mid to Late
Holocene lake level high stands, which runs counter to previous research
finding a colder and drier era with little hydrologic activity throughout
the last 5000 years.
A woman’s place: constructing women within true crime narratives
Authors: Franks Rachel 
Published: August 2021

Writers do not have to position the female body as a contested space: simultaneously conceived of as a commodity, honoured as a site of self-expression, and visualised as a vehicle for reproduction. This competition of ownership facilitates the commandeering of the female body for a variety of purposes such as the pursuit of financial or political gain. In this way, women who are central to true crime cases – as victims or as perpetrators – can be objectified by writers for the popular press in the rush to tell a story and, in some instances, marginalised, even as their stories are re-imagined. These ideas are explored through two cases that unfolded in Sydney, Australia, in the late-nineteenth century – the gang rape of Mary Jane Hicks and two murders ostensibly committed by Louisa Collins. A brief examination of the contemporary coverage of these cases unpacks how the bodies of both women were conscripted by writers for other purposes – first, to sell papers, and second, to argue for the abolition of the death penalty. This article then looks at the re-telling of these events in Frank C. Johnson’s Famous Detective Stories, which allowed mid-twentieth century true crime writers to re-ignite debates around publishing and punishment found in the original reportage. Almost 130 years after the first of these crimes took place, this article contends offering a feminist framework to review these, and similar, cases demonstrate circulation figures and discussions around the ethics of punishment are not dependent upon the appropriation of the female body.
‘Conflict cinema’ and hostile space in Northern Ireland and Palestine
Authors: Harrington Louise 
Published: August 2021

This article is concerned with narratives of ethno-religious conflict depicted in a genre I term ‘conflict cinema’. The two films under discussion, ’71 and Paradise Now, are largely set, respectively, in the cities of Belfast in Northern Ireland and Nablus in Palestine and represent the divisions and violent tension between enemy factions there. The intersection of the landscape of the conflicts and the bodies of the male protagonists who must negotiate them emphasizes the centrality of physically being ‘in place’ or ’out of place’ to ‘conflict cinema’. The soldier/colonizer Gary Hook in ’71 and the freedom fighters/terrorists Said and Khaled in Paradise Now travel through the enduring battlegrounds of their divided and politically unstable societies. Against the backdrop of ethno-religious conflict, both films focus on the ideal militant body that must be a machine or an automaton. I argue that through the screenwriters’ and filmmakers’ depiction of these bodies’ negotiations of conflict space, or in other words, the interface between the body and the unstable, urban conflict zone, ‘conflict cinema’ upsets overdetermined notions of the male militant body, thus manifesting the paradox of the dehumanised body that is also innately human.
Reverberation and the parodic: an invitation to the spaces of sound
Authors: Scicluna Josephine 
Published: August 2021

In The Politics of Aesthetics Jacques Rancière speaks of artistic practices ’as ways of “doing and making” that intervene in the general distribution of ways of doing and making’ (2013: 8). ‘Reverberation’ in the various dimensions explored by this paper is the compelling and parodic force, which signals the transformative potential of the spaces of music, word and sound collaborations. This paper will present the mixed impulse of parody as repetition with difference in Deleuze’s sense, or ironic ‘transcontextualisation’ (Hutcheon 2000: 32), contextualised by Foucault’s heterotopic thought, Steve Reich’s minimalist music, and Brian Eno’s recognition of ambient sound in 1975 (Howard 2004: 91). Also explored is Hutcheon’s investigation of the etymology of parody as ‘counter-song’, which suggests intimacy and accord. The latter understanding of parody will be of particular importance in a discussion of New Yorkbased band, The National.