bluuebunny/crossref_metadata_2025_split huggingface dataset:
South Africa in the Installation Phase of a New Techno-economic Paradigm
Authors: Stewart Peter 
Published: August 2021

Abstract
South Africa’s situation of financialization, low growth, unemployment, and inequality is linked here to the ‘installation phase’ of a new technology as described by Carlotta Perez. South Africa’s informational economy is examined, and the role of the financial sector is summarized. The article then considers the strengths and weaknesses of the manufacturing and service sectors, and the embeddedness in them of digital technologies. The article concludes by supporting manufacturing as the best route to a new productive economic core while other sites of digital industry take deeper root. The need to shape finance to more national ends is also affirmed.
Does Linguistic Similarity Affect Early Simultaneous Bilingual Language Acquisition?
Authors: Gampe Anja , Quick Antje Endesfelder , Daum Moritz M. 
Published: August 2021

Abstract
It is well established that L2 acquisition is faster when the L2 is more closely related to the learner’s L1. In the current study we investigated whether language similarity has a comparable facilitative effect in early simultaneous bilingual children. The similarity between each bilingual child’s two languages was determined using phonological and typological scales. We compared the vocabulary size of bilingual toddlers learning different pairs of languages. Results show that the vocabulary size of bilingual children is indeed influenced by similarity: the more similar the languages, the larger the children’s vocabulary.
Emergence of a Bilingual Grammar: Word Order Differences in Monolingual Basque vs. Bilingual Basque-Spanish Predicative Constructions
Authors: Lantto Hanna 
Published: August 2021

Abstract
This article compares the monolingual Basque predicative constructions with bilingual Basque-Spanish predicative constructions. The speech data for the study were collected in the Greater Bilbao area of the Basque Country between 2005 and 2012. The results suggest that code-switching may trigger the convergence of predicative constructions and have a significant impact on the general word order patterns. The monolingual predicative constructions in the data mostly follow the canonical Basque sxv word order (~81%), but the bilingual predicative constructions diverge from this word order in that the predicative element is located in a post-verbal position, as in Spanish (~80%). The Spanish lexical elements seem to be strongly associated with the corresponding Spanish construction, the word order of which is then applied to otherwise Basque predicative constructions. I explain the predominance of the Spanish word order in the bilingual constructions by a combination of processing-related factors and sociolinguistic factors.
Directional Idioms in English and Welsh: A Usage-Based Perspective on Language Contact
Authors: Rottet Kevin J. 
Published: August 2021

Abstract
The English verb-particle construction or phrasal verb (pv) has undergone dramatic semantic extensions from the expression of literal motion events (the ball rolled down the hill) – a pattern known as satellite-framing – to idiomatic figurative uses (the company will roll out a new plan) where selection of the particle is motivated by Conceptual Metaphors. Over the course of its long contact with English, Welsh – also satellite-framed with literal motion events – has extended the use of its verb-particle construction to replicate even highly idiomatic English pv s. Through a case study of ten metaphorical uses of up and its Welsh equivalent, we argue that this dramatic contact outcome points to the convergence by bilingual speakers on a single set of Conceptual Metaphors motivating the pv combinations. A residual Celtic possessive construction (lit. she rose on her sitting ‘she sat up’) competes with English-like pv s to express change of bodily posture.
Complex Items and Units in Extra-Sentential Code Switching. Spanish and English in Gibraltar
Authors: Goria Eugenio 
Published: August 2021

Abstract
As is well-known, code-mixing is particularly frequent at clause boundaries and with elements expressing pragmatic meaning. However, most of the literature has focussed on switching of simple elements such as conjunctions and discourse markers. This paper, in contrast, analyses clause peripheral switching involving two complex constructions: left dislocations and pseudo-clefts. The data are from English-Spanish bilingual conversations recorded in Gibraltar. A great majority of the bilingual constructions in the corpus belong to a few types occurring with a restricted set of lexical items. A vast amount of such highly recurrent strings in the data confirm the hypothesis that complex multi word strings that are switched together constitute units in code-mixing, i.e. they are processed as single lexical items.
Investigating a Substance Abuse Screening in a Trauma Setting
Authors: Tuli Rahul , Romero Stephanie Anne , Figueroa Cesar , Tay Erika , Saadat Soheil , Barrios Cristobal 
Published: August 2021

Introduction Drug and alcohol consumption are often associated with trauma-related injuries. Various studies have been conducted which have shown the benefits of screening and brief intervention (SBI) tools for alcohol consumption. Despite their success, there are few SBI tools utilized for substance use and minimal reports of computerized versions. We hypothesized that a computerized SBI tool for drug use would be effective at identifying patients at risk of substance abuse in a trauma setting. Methods This was a prospective evaluation of a computerized alcohol and drug screening and brief intervention survey derived from the National Institute on Drug Abuse. The survey was given to all eligible trauma patients at UCI’s Level 1 trauma facility between February 2019 and March 2020. Based on self-reported answers, a substance involvement (SI) score was generated which classified a patient’s drug abuse risk as none (0), low (1-3), moderate (4-26), or high (27+). Statistical tests were then used to examine associations between demographic variables and risk categorization. Results A total of 1801 patients completed the entire survey. Of those, 346 (19.3%) patients reported use of illicit drugs: 10 for non-medical prescription use (.6%), 308 (17.1%) for non-prescription drug use, and 28 (1.6%) for both. Secondary analysis revealed a greater number of males were eligible for further SI assessment (25.1% vs 11.0%, P < .001). Of those, a greater proportion of men were classified as moderate/high risk (81.6% vs 61.5%, P < .001). Further breakdown revealed a greater proportion of patients ≤25 years old reported use of drugs compared to >85 years old (37.0% vs .5%, P < .001). In contrast to the self-reported data, there was an overall positive rate of toxicology of 48.51%. Conclusion The analysis shows that the electronic survey identifies patients at risk of drug abuse, allowing for real-time intervention. Furthermore, it is granular enough to specify at-risk groups. However, a lower self-reported rate, as expected, was elucidated. Further studies to evaluate for improved screening and targeted intervention are warranted.
Combating misinformation: The effects of infographics in verifying false vaccine news
Authors: Domgaard Shawn , Park Mina 
Published: August 2021

Objective: False news about vaccination shared in digital spaces is a major problem that harms informed health choices. Drawing from processing fluency theory, we propose that an infographic – a visual representation of information – reduces cognitive load, thereby helping people retain and process the necessary information to discern truth from falsehood in health news. Design: Web-administered experiment. Setting: US web-based experiment on Qualtrics. Method: A national sample of participants was randomly assigned to one of the three conditions: a news literacy infographic, the same information but text-only, or a control group (a blank page). After the short intervention, study participants were shown false news about vaccinations and asked to make judgements about this news. Results: Our study found that people in the infographic condition were better able to verify false news than others. They also showed lower trust in false news articles and higher confidence in their judgement than those in the control condition. Conclusion: Findings further our understanding of how visuals accompanied by text, such as an infographic, can improve the quality of health education. During the current problem of digital spaces filled with misinformation, using a short intervention with visuals can help audiences determine the credibility of information they encounter about vaccines.
Impact of Environmental Tax on Comparative Advantage of Food and Food Products: A Study of G20 Countries in Light of Environmentally Sensitive Goods
Authors: Mahajan Alisha , Majumdar Kakali 
Published: August 2021

Many countries are under constant fear that environmental policies might negatively influence the international competitiveness of polluting industries. In this study, we aim to evaluate the relationship and impact of the environmental tax on comparative advantage of trade in food and food products industry, considered to be one of the highly environmentally sensitive industries. This study also investigates, whether this relationship differs among countries covered in G20, with the help of correlation analysis. We select panel autoregressive distributed lag approach for this study as it can analyse long-run as well as short-run association even when the variables are stationary at different orders of integration. Using panel data from G20 countries over the period of 21 years that is from 1994 to 2015, it is concluded that when we allow environmental taxes to interact with the revealed comparative advantage (RCA) of G20 nations, the overall impact of the environmental tax on the RCA is negative in the long period. It is therefore suggested that countries should follow Porter hypothesis to stimulate innovations resulting from strict environmental regulations that affect the environment in least possible manner. JEL Codes: C01, C23, C33, F18, O57, Q5
E-scooter accidents: A rising cause of kidney injury
Authors: Bianchi Alberto , Gallina Sebastian , Cianflone Francesco , Tafuri Alessandro , Cerruto Maria Angela , Antonelli Alessandro 
Published: August 2021

Introduction: E-scooters recently gained mass expansion, leading to increased use-related injuries, most commonly head trauma, facial, and extremity fractures, while abdominal trauma with kidney involvement is less frequent. Here we present two cases of e-scooter-related high-grade blunt kidney trauma. Case reports: The first case was a 24-year-old male presenting with right abdominal pain after e-scooter autonomous right fall. Focused assessment with sonography for trauma (FAST) was negative, while abdominal CT showed a 3 cm middle-renal laceration. Six-day CT showed minimal urinary extravasation. Neither anemization nor impaired kidney function was observed; the patient was discharged after 9 days. The second case was a 42-year-old male presenting with right flank pain and ipsilateral chest pain after autonomous right fall. Thoracic X-ray revealed multiple rib fractures, while abdominal echography showed a non-homogeneous right kidney with a 1.5 cm perirenal fluid layer. Abdominal CT revealed 2.5 × 4 × 3.5 cm full-thickness middle-upper renal parenchyma laceration and confirmed the perirenal hematoma, while demonstrating two hepatic lesions. A series of CT and ultrasounds confirmed the stability of the aforementioned lesions and reduction of the perirenal hematoma; laboratory findings didn’t show anemization nor impaired renal function. The patient was discharged after 10 days. Discussion: Widespread usage of e-scooter is accompanied by an uptick in traumatic events. The chance of renal trauma increases when lateral fall occurs. In our cases patients were hemodynamically stable, the kidney injury severity was high-grade, and non-operative management was effective. Conclusion: E-scooter accidents could lead to high-grade renal injuries, amenable of non-operative management; these events are expected to raise.
Socioeconomic Position and Late-Onset Dementia: A Nationwide Register-Based Study
Authors: Appel Andreas M. , Brønnum-Hansen Henrik , Garde Anne H. , Hansen Åse Marie , Ishtiak-Ahmed Kazi , Islamoska Sabrina , Mortensen Erik L. , Osler Merete , Nabe-Nielsen Kirsten 
Published: August 2021

Objectives Previous research on the association between socioeconomic position (SEP) and dementia has not sufficiently accounted for the complex relationship between education and occupation. We investigated the independent and joint effects of educational attainment and occupation-based SEP on dementia. Methods We used register-based information about educational attainment, occupation-based SEP, and dementia from 1,210,720 individuals. Information about cognitive ability at conscription was available for a subsample of men. Results When mutually adjusted, lower educational attainment and occupation-based SEP were associated with higher dementia risk in a dose–response manner. Higher occupation-based SEP partly mitigated the higher dementia risk associated with lower educational attainment. After adjusting for cognitive ability in a subgroup of men, only unskilled work was associated with higher dementia risk. Discussion Occupation-based SEP is independently associated with dementia and may mitigate the higher dementia risk associated with short education. Future research should elucidate the mechanisms underlying social inequality in dementia.
Invasive Microsporum canis infection as a presenting complaint of late-diagnosed HIV infection
Authors: Xia Xiu-Jiao , Liu Ze-Hu 
Published: August 2021

A 43-year-old male barber presented with 1 year history of a painful, itchy plaque on the dorsal hand. Microsporum canis was recovered from pus of the lesion. Serologic testing for human immunodeficiency virus (HIV) antibody was positive, with a CD4+ count of 81 cells per cubic millimeter. Invasive cutaneous Microsporum canis infection is uncommon and can be suggestive of HIV infection or other conditions of immunocompromise.
Chlamydia trachomatis anorectal infections by LGV (L1, L2 and L2b) and non-LGV serotypes in symptomatic patients in Buenos Aires, Argentina
Authors: La Rosa Luciana , Svidler López Laura , Entrocassi Andrea C , López Aquino Deysi , Caffarena Dolores , Büttner Karina A , Gallo Vaulet María L , Rodríguez Fermepin Marcelo 
Published: August 2021

Background Chlamydia trachomatis (CT) can infect the anorectum producing various signs and symptoms. There is scarce literature regarding the differences between LGV and non-LGV CT anorectal manifestations. We compare the clinical spectrum of LGV and non-LGV infections. Methods Patients over 18 years with presumptive infectious anorectal symptoms were examined in two healthcare centres in Buenos Aires. The patients were studied and treated according to current sexually transmitted infection guidelines. Anorectal swabs were collected to detect and genotype CT. Results A three-year-long study on 317 patients with anorectal symptoms showed 45.11% CT infection (85% LGV strains). Of 140 samples, 92 were sequenced: 80/119 LGV (L2b 45%, L1 32.5% and L2 22.5%) and 12/21 non-LGV. Older age and HIV+ status were significantly higher in the LGV group. Anal discharge, bleeding, severe proctitis and anal ulcers were more common in the LGV group. Multivariate logistic regression analysis revealed that HIV infection, anorectal bleeding and oro-anal sex are independent predictors of LGV infection. Conclusions In patients with anorectal symptoms, LGV serovars predominate over non-LGV ones. Clinical manifestations are not pathognomonic of a specific biovar. If genotyping is not available, having clinical predictors may help to presume an LGV infection and define length of treatment.
Experimental and artificial neural network approach for prediction of dynamic mechanical behavior of sisal/glass hybrid composites
Authors: Ornaghi Heitor Luiz , Monticeli Francisco M , Neves Roberta Motta , Zattera Ademir José , Amico Sandro Campos 
Published: August 2021

The dynamic mechanical behavior (storage modulus, loss modulus, and tan δ) of hybrid sisal/glass composites was investigated in the temperature range of 30–210 °C, for two different volume percentages of reinforcement along with the different ratios of sisal and glass fibers. Based on the experimental outcome, an artificial neural network (ANN) approach was used to predict the dynamic mechanical properties followed by a surface response methodology (SRM). The ANN analysis showed an excellent fit with the storage modulus, loss modulus, and tan δ experimental data. In addition, the fitted curves with the ANN approach were used to propose equations based on SRM. The simulation result has shown that the ANN is a potential mathematical tool for the structure–property correlation for polymer composites and may help researchers in the development and application of their data, reducing the need for long experimental campaigns.
Central retinal thickness fluctuations in patients treated with anti-VEGF for neovascular age related macular degeneration
Authors: Ciucci Francesco , Ioele Giuseppina , Bardocci Antonio , Lofoco Giorgio , Antonelli Barbara , Gaetano Cristiano De , Polimanti Gabriele , Luca Michele De , Ragno Gaetano , Gattegna Roberto 
Published: August 2021

Purpose: This is a retrospective, single-center, non randomized interventional real life study, investigating the correlation between variability of central retinal thickness (CRT) and functional outcomes during 2 years of anti-VEGF therapy in patients treated for neovascular age related macular degeneration (nAMD). Background: CRT fluctuations can depend on various factors such as the correct timing of injections, the therapeutic algorithm, and the number of injections (NI) performed; it is important to understand if CRT fluctuations are responsible for worse visual outcomes and consequently to identify the correct ways to avoid or reduce them. Methods: Forty-one patients were treated for nAMD with aflibercept: 0.5 mg intravitreal aflibercept was administered every 4 weeks during the first 3 months, then bimonthly over the first year, and after the first year adopting a PRN regimen. Standard deviation of CRT (CRT/SD), BCVA, and NI were recorded. Correlation studies were performed by Pearson’s test, Ancova, and Principal Component Analysis. Results: A negative correlation was found between CRT/SD and final BCVA. In patients who lost more than 15 letters, CRT/SD mean was significantly higher in comparison with patients who lost less than 15 letters. Patients with final BCVA >65 letters showed lower CRT/SD values compared to patients with final BCVA ⩽65 letters. Multivariate analysis confirmed that in patients with higher baseline BCVA, improvement of BCVA was correlated to NI, and lower values of CRT fluctuations were observed. Conclusions: CRT fluctuations, even after an appropriate NI given per year, significantly influence BCVA; a proactive treatment algorithm appears crucial when treating patients with nAMD.
Clinicopathological Examination of Metaplastic Spindle Cell Carcinoma of the Breast: Case Series
Authors: Ishizuka Yumiko , Horimoto Yoshiya , Yanagisawa Naotake , Arakawa Atsushi , Nakai Katsuya , Saito Mitsue 
Published: August 2021

Background: Spindle cell carcinoma (SpCC) of the breast is a rare histological type, a subtype of metaplastic carcinoma characterized by atypical spindle cell and epithelial carcinoma. The proportions of the spindle cell and epithelial components vary among tumours. Due to its rarity, biological characteristics of this disease have been poorly studied. Methods: In total, 10 patients with SpCC were surgically treated at our institution from January 2007 to December 2018. We retrospectively investigated these SpCC cases, focusing on the differences between spindle cell and epithelial components. Microsatellite status was also examined. Results: Nine cases were triple-negative breast cancer (TNBC). The rates of high tumour grade were 70% in spindle cell components and 56% in epithelial components ( P = .65), while the mean Ki67 labelling index were 63% and 58%, respectively ( P = .71). Mean programmed death ligand 1 (PD-L1) expression in these components was 11% and 1%, respectively ( P = .20). All 10 tumours were microsatellite stable. Patient outcomes of triple-negative SpCC did not differ from those of propensity-matched patients with conventional TNBC. Conclusions: Spindle cell components showed higher values in factors examined, although there was no statistically significant difference. Our data reveal that these 2 components of SpCC may be of different biological nature.
The Impact of Acne Treatment on Skin Bacterial Microbiota: A Systematic Review
Authors: Lam Megan , Hu Angie , Fleming Patrick , Lynde Charles W. 
Published: August 2021

Background Microbial strains such as Cutibacterium acnes have been examined as contributors to the pathogenesis of acne. Given the prevalence of the disease among adolescents and adults, the overutilization of antimicrobial agents may breed resistance and alter commensal microflora. Objectives To characterize the impact of acne treatment on the diversity and relative abundance of the cutaneous microbial community, particularly of the bacterial flora Methods An electronic search was conducted of Embase, MEDLINE, and the Cochrane Central Register of Controlled Trials (CENTRAL) on June 5, 2020. Interventional and observational studies examining patients receiving acne treatment with culture-independent, community-level analysis of the cutaneous microbiome were included. Results Nine studies with 170 treated acne patients were included. Five studies reported a significant change in alpha diversity following treatment, 3 of which examining systemic antibiotics reported significant increases in diversity. Two of 3 studies examining effects of benzoyl peroxide reported a decrease in diversity. However, trends in diversity were heterogeneous among studies. Conclusions While individual variability in microbiome composition, and study-level heterogeneity in study sampling techniques may limit quantitative synthesis, our results support findings that acne treatment, including those not considered to have antimicrobial properties, alters the composition of the cutaneous microbiome. PROSPERO registration: CRD42020190629
Risk of Developing Melanoma With Systemic Agents Used to Treat Psoriasis: A Review of the Literature
Authors: Semaka Amy , Salopek Thomas G. 
Published: August 2021

Background Psoriasis is a chronic inflammatory skin disease induced by autoimmune-like dysregulation of the immune system. Treatment options have drastically evolved in recent years, and treatment advances that target specific cytokines and other molecules involved in dysregulation have had a profound effect in controlling the disease. Objective We reviewed the literature to assess the risk of developing melanoma with conventional therapies and newer agents used to treat psoriasis. Methods A comprehensive literature search using Medline (via Ovid) and Embase was conducted. Results The majority of studies reviewed reported insignificant results. Potential risk for melanoma was identified for only 3 out of 15 anti-psoriatic treatments analyzed: adalimumab (relative risk 1.8, 95% CI 1.06-3.00), etanercept (relative risk 2.35, 95% CI 1.46-3.77) and infliximab (Empirical Bayes Geometric Mean 7.90, 95% CI 7.13-8.60). The confidence intervals provided are from prior studies. There are not enough collective data on newer agents to make any conclusions on risk. Conclusions We were unable to identify any substantial risk for developing melanoma due to the use of anti-psoriatic treatments. Until additional long-term registry data become available, it would be prudent to continue screening patients with psoriasis at baseline and periodically for melanoma when these agents are used.