bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of Various Traumatic Events Including Sexual Trauma in a Clinical Sample of Patients With an Eating Disorder
Authors: Kjaersdam Telléus Gry , Lauritsen Marlene Briciet , Rodrigo-Domingo Maria 
Published: August 2021

Objective: Eating disorder (ED) and trauma have often been associated, and there is evidence that early experiences of traumatic events are associated with subsequent ED. Research results point toward an increased prevalence of sexual trauma in individuals with ED, and it has been suggested that sexual trauma precedes and contributes to the development of ED. The aim of this study was to assess the prevalence of sexual trauma as well as other types of traumatic life events in a clinical sample of children, adolescents, and adults with ED.Method: Patients (N = 329), median age 16.9 [Interquartile Range (IQR):4.5], diagnosed with various EDs in a specialized ED unit were included.Results: The majority (67%) of patients with ED reported at least one traumatic life event at time of assessment such as bullying (32%), loss (24%), or accidents (11%). Nineteen per cent of the patients reported having been the victim of a sexual trauma or another sexual traumatic event distributed as follows in terms of severity: 13% had been the victim of a negative experience associated with sex; 57% reported having experienced sexual assault other than rape; and 30% had been the victim of severe forms of sexual assault. The median time between the sexual trauma and the ED diagnosis was 3.4 years (IQR: 6.6). The median time between the sexual trauma and the onset of ED symptoms was 0 years (IQR: 5). The study results imply that the sexual trauma could be experienced either prior to or after onset of ED symptoms.Conclusions: Sixty-seven per cent of the patients with an ED reported traumatic life events at time of assessment, whereby 19% reporting negative sexual experiences or sexual abuse. However, sexual trauma does not necessarily play a causal role in the development of EDs.
Quantifying the Impact of Phenoconversion on Medications With Actionable Pharmacogenomic Guideline Recommendations in an Acute Aged Persons Mental Health Setting
Authors: Mostafa Sam , Polasek Thomas M. , Sheffield Leslie J. , Huppert David , Kirkpatrick Carl M. J. 
Published: August 2021

Introduction: Polypharmacy and genetic variants that strongly influence medication response (pharmacogenomics, PGx) are two well-described risk factors for adverse drug reactions. Complexities arise in interpreting PGx results in the presence of co-administered medications that can cause cytochrome P450 enzyme phenoconversion.Aim: To quantify phenoconversion in a cohort of acute aged persons mental health patients and evaluate its impact on the reporting of medications with actionable PGx guideline recommendations (APRs).Methods: Acute aged persons mental health patients (N = 137) with PGx and medication data at admission and discharge were selected to describe phenoconversion frequencies for CYP2D6, CYP2C19 and CYP2C9 enzymes. The expected impact of phenoconversion was then assessed on the reporting of medications with APRs.Results: Post-phenoconversion, the predicted frequency at admission and discharge increased for CYP2D6 intermediate metabolisers (IMs) by 11.7 and 16.1%, respectively. Similarly, for CYP2C19 IMs, the predicted frequency at admission and discharge increased by 13.1 and 11.7%, respectively. Nineteen medications with APRs were prescribed 120 times at admission, of which 50 (42%) had APRs pre-phenoconversion, increasing to 60 prescriptions (50%) post-phenoconversion. At discharge, 18 medications with APRs were prescribed 122 times, of which 48 (39%) had APRs pre-phenoconversion, increasing to 57 prescriptions (47%) post-phenoconversion.Discussion: Aged persons mental health patients are commonly prescribed medications with APRs, but interpretation of these recommendations must consider the effects of phenoconversion. Adopting a collaborative care model between prescribers and clinical pharmacists should be considered to address phenoconversion and ensure the potential benefits of PGx are maximised.
Adverse Childhood Events and Health Biomarkers: A Systematic Review
Authors: Soares Sara , Rocha Vânia , Kelly-Irving Michelle , Stringhini Silvia , Fraga Sílvia 
Published: August 2021

Background: This systematic review aimed to summarize evidence reporting epigenetic and/or neuro-immuno-endocrine embedding of adverse childhood events (ACEs) in children, with a particular focus on the short-term biological effect of those experiences.Methods: A search was conducted in PsycINFO®, PubMed®, Isi Web of Knowledge and Scopus, until July 2019, to identify papers reporting the short-term biological effects of exposure to ACEs.Results: The search identified 58 studies, that were included in the review. Regarding exposure, the type of ACE more frequently reported was sexual abuse (n = 26), followed by life stressors (n = 20) and physical abuse (n = 19). The majority (n = 17) of studies showed a positive association between ACEs and biomarkers of the immune system. Regarding DNA methylation 18 studies showed more methylation in participants exposed to ACEs. Two studies presented the effect of ACEs on telomere length and showed that exposure was associated with shorter telomere length.Conclusion: Overall the associations observed across studies followed the hypothesis that ACEs are associated with biological risk already at early ages. This is supporting evidence that ACEs appear to get “under the skin” and induce physiological changes and these alterations might be strongly associated with later development of disease.
Surgical Outcomes of Robotic Resection for Sigmoid and Rectal Cancer: Analysis of 109 Patients From a Single Center in China
Authors: Peng Jianhong , Li Weihao , Tang Jinghua , Li Yuan , Li Xueying , Wu Xiaojun , Lu Zhenhai , Lin Junzhong , Pan Zhizhong 
Published: August 2021

Background: Robotic colorectal surgery has been increasingly performed in recent years. The safety and feasibility of its application has also been demonstrated worldwide.However, limited studies have presented clinical data for patients with colorectal cancer (CRC) receiving robotic surgery in China. The aim of this study is to present short-term clinical outcomes of robotic surgery and further confirm its safety and feasibility in Chinese CRC patients.Methods: The clinical data of 109 consecutive CRC patients who received robotic surgery at Sun Yat-sen University Cancer Center between June 2016 and May 2019 were retrospectively reviewed. Patient characteristics,tumor traits, treatment details, complications, pathological details, and survival status were evaluated.Results: Among the 109 patients, 35 (32.1%) had sigmoid cancer, and 74 (67.9%) had rectal cancer. Thirty-seven (33.9%) patients underwent neoadjuvant chemoradiotherapy. Ten (9.2%) patients underwent sigmoidectomy, 38 (34.9%) underwent high anterior resection (HAR), 45 (41.3%) underwent low anterior resection (LAR), and 16 (14.7%) underwent abdominoperineal resection (APR). The median surgical procedure time was 270 min (range 120–465 min). Pathologically complete resection was achieved in all patients. There was no postoperative mortality. Complications occurred in 11 (10.1%) patients, including 3 (2.8%) anastomotic leakage, 1 (0.9%) anastomotic bleeding, 1 (0.9%) pelvic hemorrhage, 4 (3.7%) intestinal obstruction, 2 (1.8%) chylous leakage, and 1 (0.9%) delayed wound union. At a median follow-up of 17 months (range 1–37 months), 1 (0.9%) patient developed local recurrence and 5 (4.6%) developed distant metastasis, with one death due to disease progression.Conclusions: Our results suggest that robotic surgery is technically feasible and safe for Chinese CRC patients, especially for rectal cancer patients who received neoadjuvant treatment. A robotic laparoscope with large magnification showed a clear surgical space for pelvic autonomic nerve preservation in cases of mesorectal edema.
Total Psoas Muscle Area as a Marker for Sarcopenia Is Related to Outcome in Children With Neuroblastoma
Authors: Ritz Annika , Froeba-Pohl Alexandra , Kolorz Julian , Vigodski Victor , Hubertus Jochen , Ley-Zaporozhan Julia , von Schweinitz Dietrich , Häberle Beate , Schmid Irene , Kappler Roland , Lurz Eberhard , Berger Michael 
Published: August 2021

Background: Sarcopenia describes a generalized loss of skeletal muscle mass, strength, or function. Determined by measuring the total psoas muscle area (tPMA) on cross-sectional imaging, sarcopenia is an independent marker for poor post-surgical outcomes in adults and children. Children with cancer are at high risk for sarcopenia due to immobility, chemotherapy, and cachexia. We hypothesize that sarcopenic children with neuroblastoma are at higher risk for poor post-operative outcomes.Patients and Methods: Retrospective analysis of children with neuroblastoma ages 1–15 years who were treated at our hospital from 2008 to 2016 with follow-up through March 2021. Psoas muscle area (PMA) was measured from cross-sectional images, using computed tomography (CT) and magnetic resonance imaging (MRI) scans at lumbar disc levels L3-4 and L4-5. tPMA is the sum of the left and right PMA. Z-scores were calculated using age- and gender-specific reference values. Sarcopenia was defined as a tPMA z-score below −2. A correlation of tPMA z-scores and sarcopenia with clinical variables and outcome was performed.Results: One hundred and sixty-four children with workup for neuroblastoma were identified, and 101 children fulfilled inclusion criteria for further analysis, with a mean age of 3.92 years (SD 2.71 years). Mean tPMA z-score at L4-5 was −2.37 (SD 1.02). Correlation of tPMA z-score at L4-5 with weight-for-age z-score was moderate (r = 0.54; 95% CI, 0.38, 0.66). No association between sarcopenia and short-term outcome was observed. Sarcopenia had a sensitivity of 0.82 (95% CI, 0.62–0.93) and a specificity of 0.48 (95% CI 0.36–0.61) in predicting 5-year survival. In a multiple regression analysis, pre-operative sarcopenia, pre-operative chemotherapy in the NB2004 high-risk group, unfavorable tumor histology, and age at diagnosis were associated with 5-year survival after surgery, with hazard ratios of 4.18 (95% CI 1.01–17.26), 2.46 (95% CI 1.02–5.92), 2.39 (95% CI 1.03–5.54), and 1.01 (95% CI 1.00–1.03), respectively.Conclusion: In this study, the majority of children had low tPMA z-scores and sarcopenia was a risk factor for decreased 5-year survival in children with neuroblastoma. Therefore, we suggest measuring the tPMA from pre-surgical cross-sectional imaging as a biomarker for additional risk stratification in children with neuroblastoma.
Relaciones tempranas y nacimiento del self
Authors: Sassaroli Sandra , Lorenzini Roberto 
Published: August 2021

Este articulo versa sobre nuestra hipotesis acerca del nacimiento de la idea del otro y del Self en un sistema cognitivo que vive y aprende. Este nacimiento tiene origen en la relacion de vinculacion. Presentaremos nuestra hipotesis sobre la filiacion de las relaciones de vinculacion y apego, que este de acuerdo con el principio motivacional .
El aumento de la capacidad predictiva y, sobre la base de estas premisas, revisaremos las teorias tradicionales de la vinculacion desde Bowlby hasta la actualidad. Por ultimo, reexaminaremos nuestros trabajos previos y estableceremos nuevas conexiones entre los tipos de relaciones de vinculacion las reglas que gobiernan la adquisicion del conocimiento (criterios epistemologicos).
Los efectos patógenos de la psicoterapia
Authors: Semerari Antonio 
Published: August 2021

Pademos considerar la psicoterapia como un proceso capaz de cambiar las estructuras de significado de una persona tanto para mejorar como para empeorar. Este articulo se propone superar una dimension anecdotica de las errores en la terapia y afrontar los efectos patogenos a partir de observaciones clinicas intentando dar respuesta a tres tipos de cuestiones relativas a:
a ) Determinar la fenomenologia clinica de la patologia indicada por la psicaterapia .
b) Analizar primero de que mecanismos directos de relacion entre terapia y paciente pueden originarse.
c ) Detectar los indicios precoces de cambia patogeno que pueden servir al terapeuta para modificar sus intervenciones.
Sobre la elaboracion del duelo en terapia familiar
Authors: Espina Alberto , Gago Josu , Pérez María Mar 
Published: August 2021

La elaboracion del duelo desde los origenes de la psicologia y de la psicoterapia con la depresion .En este articulo se trata del estudio de los fenomenos de duelo desde una perspectiva cientifica y con una aproximacion clinica de inspiracion sistemica .
Counseling y psicoterapia desde una perspectiva evolutiva
Authors: Marcia James E 
Published: August 2021

En este articulo se vera la relacion entre tres enfoques teoricos en la psicologia evolutiva: la teoria psicoanalitica del ego. La teoria de las relaciones objetales, y la teoria del desarrollo cognitivo. Se parte del supuesto que los tres postulan objetivos con procesos similares. Todos juntos ofrecen el marco de trabajo para el desarrollo del counseling de la psicoterapia. Se ilustran algunos puntos concretos con casos clinicos.
La entrevista evolutiva
Authors: Villegas Besora Manuel 
Published: August 2021

En este articulo se considera la entrevista terapéutica como una clase particular de discurso que puede ser analizado a dos niveles : a) expresivo, relativo a la complejidad epistemologica ‹le su enunciacion y b) constructivo, relativo al grado de desarrollo socio-cognitivo que manifiesta. Esta doble perspectiva, se basa en la descripcion constructivo-genética de Jean Piaget y su escuela, ofrece una vision evolutiva de la entrevista terapéutica y da origen a un modelo de analisis aplicable a cualquier entrevista, independientemente del modelo de adscripcion del terapeuta.
Los modelos teóricos , los tratamientos y las entrevistas de evaluación en la asistencia clínica en salud mental : informe sobre una encuesta realizada los C. A.P y C.A.P.I.P de Catalunya
Authors: Mitjavila Merce , Miró María Teresa , Bachs Jordi 
Published: August 2021

El motivo de la realizacion de este estudio descriptivo parte de la reflexion , acerca de la diversidad de modelos en el campo de la psicologia , psicologia cademica y psicologia aplicada.
Toxocara Seroprevalence and Risk Factor Analysis in Four Communities of the Wiwa, an Indigenous Tribe in Colombia
Authors: Waindok Patrick , Kann Simone , Aristizabal Andrés , Dib Juan Carlos , Strube Christina 
Published: August 2021

The life of the indigenous Wiwa tribe in northeast Colombia is characterized by lacking access to clean drinking water and sanitary installations. Furthermore, free-roaming domestic animals and use of yucca and/or manioc as a primary food source favor the transmission of soil-transmitted helminths, e.g., Toxocara canis and Toxocara cati, the roundworms of dogs and cats. Infection may result in the clinical picture of toxocarosis, one of the most common zoonotic helminthoses worldwide. To estimate the Toxocara seroprevalence in four different villages of the Wiwa community, serum samples from 483 inhabitants were analyzed for anti-Toxocara-antibodies. Overall, 79.3% (383/483) of analyzed samples were seropositive. Statistically significant differences were observed between the four villages, as well as age groups (adults > adolescents > children), while sex had no effect. The high seropositivity rate demonstrates the risk of zoonotic roundworm infections and potential clinical disease in vulnerable indigenous inhabitants.
PELATIHAN IDENTIFIKASI FORMALIN DAN BORAKS PADA MAKANAN SECARA SEDERHANA DI KELURAHAN PAMIJEN KABUPATEN BANYUMAS
Authors: Fitriana Adita Silvia , Royani Sri 
Published: August 2021

Formalin and borax are dangerous chemicals that are often misused as food preservatives. Various inspections have been carried out to minimize the use of formalin and borax in food, but there are still many formalin and borax in foods. The community, especially housewives, should have the ability to identify the presence of formalin and borax in food in order to protect family members from the exposure of those chemicals. Housewives in Pamijen Sub-District do not have knowledge and skills to identify formalin and borax content in food yet. Through this community service program, housewives in Pamijen Sub-District are expected to be able to test formalin and borax content in food independently. The program began with counseling about the food characteristics that contains formalin and borax; and the impact on health. This program continued with training on how to identify and practicing on how to detect formalin and borax in some food samples with a simple and an easy method. The results indicate that this program can increase patricipants’ knowledge about formalin and borax; and skills to identify them.
Keywords: preservatives, formalin, borax, food
Effect of Collaborative Writing Combined with Blog Online Learning on Indonesian EFL Learners’ Writing Skill across Motivation
Authors: Rahayu Rizki Anugrah Putri 
Published: August 2021

Abstract:

This study aims to investigate collaborative writing combined with blog online learning on the writing skill of Indonesian English foreign language (EFL) learners’ across their motivation. This research included a quasi experimental with the comparative time series. A quasi experimental study was employed by involving 61 learners of Senior High School. This research applied in into two groups: experimental and control. The treatment was conducted at 7 sessions, including the pre-test and post-test. The scores of pre-test and post-test in writing were used as a base of quantitative data analysis whereas the learners’ responses to motivation questionnaire were used to categorize their motivation. The result revealed that the collaborative writing combined with blog online learning on the writing was effective to enhance the learners’ writing skill. In addition, to apply the combination of collaborative writing and online blog learning, teacher should not worry about different levels of motivation among students where the students were motivated to use language.
HUMANIZATION OF BODY PENALTIES APPLIED TO THE MINISTERS OF THE CHURCH
Authors: Логунова Любовь Евгеньевна 
Published: August 2021

В XVIII в. служители церкви, не преодолев еще существующих ранее сложностей, вынужденно столкнулись с новыми проблемами в виде непростых отношений со светской государственной властью. Священнослужители, являясь на тот момент обособленной сословной группой, во многом привилегированной, в то же время наказывались за отдельные проступки и преступления наравне с представителями податных сословий российского общества, в том числе и телесно. Болезненные телесные наказания в рассматриваемый период были широко применимы и разнообразны: битье кнутом, битье розгами, битье плетьми, битье шелепами, битье шпицрутенами, битье батогами и т. д. Цели назначения и применения телесных наказаний также разнились: одних наказывали с целью воспитания, наказывая других, пытались устрашить, в некоторых случаях наказание несло функцию превенции и т. п. Законодатель в рассматриваемый исторический период увидел в существующей практике применения телесных наказаний противоречие между важной социальной ролью, определяемой государством и церковью для церковнослужителей и их реальным положением в социуме. Анализ путей преодоления законодателем и церковной властью этого противоречия и явился целью настоящего исследования.
In the XVIII century, the ministers of the church, not having overcome the difficulties that still existed earlier, were forced to face new problems, in the form of difficult relations with the secular state power. The clergy, being at that time, a separate class group, largely privileged, at the same time, were punished for individual offenses and crimes on an equal basis with representatives of the taxable classes of Russian society, including physically. Painful corporal punishments in the period under review were widely applicable and varied: whipping, whipping with rods, whipping with whips, whipping with shelepami, whipping with shpitsruten, whipping with batogami, etc. The purpose of the appointment and application of corporal punishment also varied: some were punished for the purpose of education, punishing others, trying to intimidate, in some cases the punishment had the function of prevention, etc. The legislator in the historical period under review saw in the existing practice of the use of corporal punishment a contradiction between the important social role defined by the state and the church for churchmen and their real position in society. The purpose of this study is to analyze the ways in which the legislator and the church authorities overcome this contradiction.
Elevated ad libitum alcohol consumption following continuous theta burst stimulation to the left-dorsolateral prefrontal cortex is partially mediated by changes in craving
Authors: McNeill Adam M. , Monk Rebecca L. , Qureshi Adam W. , Makris Stergios , Cazzato Valentina , Heim Derek 
Published: August 2021

AbstractPrevious research indicates that following alcohol intoxication, activity in prefrontal cortices is reduced, linking to changes in associated cognitive processes, such as inhibitory control, attentional bias (AB), and craving. While these changes have been implicated in alcohol consumption behaviour, it has yet to be fully illuminated how these frontal regions and cognitive processes interact to govern alcohol consumption behaviour. The current preregistered study applied continuous theta burst transcranial magnetic stimulation (cTBS) to examine directly these relationships while removing the wider pharmacological effects of alcohol. A mixed design was implemented, with cTBS stimulation to right and left dorsolateral prefrontal cortex (DLPFC), the medial orbital frontal cortex (mOFC) and Vertex, with measures of inhibitory control, AB, and craving taken both pre- and post-stimulation.Ad libitumconsumption was measured using a bogus taste task. Results suggest that rDLPFC stimulation impaired inhibitory control but did not significantly increasead libitumconsumption. However, lDLPFC stimulation heightened craving and increased consumption, with findings indicating that changes in craving partially mediated the relationship between cTBS stimulation of prefrontal regions andad libitumconsumption. Medial OFC stimulation and AB findings were inconclusive. Overall, results implicate the left DLPFC in the regulation of craving, which appears to be a prepotent cognitive mechanism by which alcohol consumption is driven and maintained.
A Systematic Search for Outbursting AM CVn Systems with the Zwicky Transient Facility
Authors: van Roestel Jan , Creter Leah , Kupfer Thomas , Szkody Paula , Fuller Jim , Green Matthew J. , Rich R. Michael , Sepikas John , Burdge Kevin , Caiazzo Ilaria , Mróz Przemek , Prince Thomas A. , Duev Dmitry A. , Graham Matthew J. , Shupe David L. , Laher Russ R. , Mahabal Ashish A. , Masci Frank J. 
Published: August 2021

Abstract
AM CVn systems are a rare type of accreting binary that consists of a white dwarf and a helium-rich, degenerate donor star. Using the Zwicky Transient Facility (ZTF), we searched for new AM CVn systems by focusing on blue, outbursting stars. We first selected outbursting stars using the ZTF alerts. We cross matched the candidates with Gaia and Pan-STARRS catalogs. The initial selection of candidates based on the Gaia BP-RP contains 1751 unknown objects. We used the Pan-STARRS g-r and r-i color in combination with the Gaia color to identify 59 strong AM CVn candidates. We obtained identification spectra of 35 sources, of which 18 are high-priority candidates, and discovered nine new AM CVn systems and one magnetic CV that shows only He-ii lines. Using the outburst recurrence time, we estimate the orbital periods of the nine new AM CVn systems that are in the range of 29–50 minutes. We conclude that targeted follow up of blue, outbursting sources is an efficient method to find new AM CVn systems and we plan to follow up all candidates we identified to systematically study the population of outbursting AM CVn systems.