bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolic Profiling Indicates Diversity in the Metabolic Physiologies Associated With Maternal Postpartum Depressive Symptoms
Authors: Bränn Emma , Malavaki Christina , Fransson Emma , Ioannidi Maria-Konstantina , Henriksson Hanna E. , Papadopoulos Fotios C. , Chrousos George P. , Klapa Maria I. , Skalkidou Alkistis 
Published: June 2021

Background: Postpartum depression (PPD) is a devastating disease requiring improvements in diagnosis and prevention. Blood metabolomics identifies biological markers discriminatory between women with and those without antenatal depressive symptoms. Whether this cutting-edge method can be applied to postpartum depressive symptoms merits further investigation.Methods: As a substudy within the Biology, Affect, Stress, Imagine and Cognition Study, 24 women with PPD symptom (PPDS) assessment at 6 weeks postpartum were included. Controls were selected as having a score of ≤ 6 and PPDS cases as ≥12 on the Edinburgh Postnatal Depression Scale. Blood plasma was collected at 10 weeks postpartum and analyzed with gas chromatography–mass spectrometry metabolomics.Results: Variations of metabolomic profiles within the PPDS samples were identified. One cluster showed altered kidney function, whereas the other, a metabolic syndrome profile, both previously associated with depression. Five metabolites (glycerol, threonine, 2-hydroxybutanoic acid, erythritol, and phenylalanine) showed higher abundance among women with PPDSs, indicating perturbations in the serine/threonine and glycerol lipid metabolism, suggesting oxidative stress conditions.Conclusions: Alterations in certain metabolites were associated with depressive pathophysiology postpartum, whereas diversity in PPDS physiologies was revealed. Hence, plasma metabolic profiling could be considered in diagnosis and pathophysiological investigation of PPD toward providing clues for treatment. Future studies require standardization of various subgroups with respect to symptom onset, lifestyle, and comorbidities.
Vaccine Information Seeking Behavior Among Pregnant Women in Khartoum State, Sudan: A Hospital-Based Cross-Sectional Study
Authors: Sabahelzain Majdi M. , Ibrahim Zienab A. , Hamad Sahar A. B. , Finnegan Gary 
Published: June 2021

Objective: This study aims to explore vaccine information-seeking behavior and its determinants among pregnant women in Khartoum state, Sudan. The findings from this study will be used to inform further development of policies and interventions in Sudan to increase vaccine acceptance and demand.Methods: A hospital-based cross-sectional study was conducted in two public hospitals, Omdurman maternity and AL-Saudi hospitals in Omdurman, Khartoum state, from February to April 2020.Results: We interviewed 350 pregnant women in the two hospitals. Our findings showed that one-third of pregnant women (35.7%) searched for information about vaccines. The vast majority searched for this information before pregnancy and during pregnancy (34.4 and 59.2%, respectively). They primarily searched for topics related to vaccine schedules and vaccine side effects (28.8% for each). The main sources of vaccine-related information consumed by pregnant women were healthcare professionals, particularly doctors (40%), and the internet (20.8%). Findings showed that a high level of education was associated with a greater likelihood of searching for additional vaccine information. Moreover, those who perceived their family to have a high income were more likely to search for information. Additionally, pregnant women with low confidence in vaccines were more likely to be involved in searching for additional vaccine information. This highlights the need for high-quality, easily accessible information that addresses their needs.Conclusion: Our findings showed that confidence in vaccine influences seeking for relevant information. We recommend the development of client-centered communication interventions to help increasing vaccine confidence and consequently vaccine acceptance and demand.
Physical Therapists as Partners for Community Fall Risk Screenings and Referrals to Community Programs
Authors: Vincenzo Jennifer L. , Hergott Colleen , Schrodt Lori , Perera Subashan , Tripken Jennifer , Shubert Tiffany E. , Brach Jennifer S. 
Published: June 2021

Objectives: Physical therapists (PTs) are integral team members in fall prevention in clinical settings; however, few studies have investigated PTs' engagement in pro-bono community-based falls prevention. Therefore, we aimed to describe the characteristics of PTs and physical therapist assistants (PTAs) in the United States who conduct community-based fall screenings, the reach of screenings, their knowledge and utilization of the Centers for Disease Control and Prevention's fall-risk screening toolkit (STEADI, Stopping Elderly Accidents, Deaths, and Injuries), and therapists' knowledge and referrals to evidence-based programs (EBPs) and community resources.Methods: A cross-sectional survey distributed to a convenience sample of PTs/PTAs in the United States through news-blasts, and social media.Results: Four hundred and forty-four therapists who worked with older adults completed the survey. Approximately 40% of the respondents (n = 180) conduct screenings, most frequently annually. People who screen tend to be PTs with &gt;20 years of experience, work in outpatient/wellness or academia, and be involved in the least amount of direct patient care. The majority (n = 344, 77.5%) of survey respondents were somewhat to very familiar with the STEADI, and ~84% (n = 114) of respondents who were very familiar with the STEADI (n = 136) use the toolkit to conduct community-based, pro-bono fall risk screenings. Twenty-six percent (n = 14) out of the 53 PTAs who responded to the survey conduct falls screenings in the community. Of the PTs/PTAs who conduct community-based fall screenings (n = 180), ~ 75% (n = 136) are aware of and refer older adults to EBPs. Over half also refer to Silver Sneakers and/or senior centers.Discussion: PTs and PTAs are key partners in evidence-based multifactorial fall prevention in the community. Data helps inform community organizations that most PTs who engage in community-based fall risk screening utilize the STEADI toolkit and refer to community-based programs. Community organizations seeking PT partners to engage in fall risk screenings and promote referrals to local resources or EBPs will likely have the most success collaborating with local physical therapy education programs or physical therapy clinic managers.
Willingness to Participate in Alcohol Prevention Interventions Targeting Risky Drinking Employees. The WIRUS Project
Authors: Thørrisen Mikkel Magnus , Bonsaksen Tore , Skogen Jens Christoffer , Skarpaas Lisebet Skeie , Sevic Aleksandra , van Mechelen Willem , Aas Randi Wågø 
Published: June 2021

Background: The extent to which eligible individuals in a target population are willing to participate in interventions is important when evaluating the efficacy of public health interventions.Objectives: As part of a process evaluation of an ongoing randomized controlled trial, this study aimed to identify the proportion of risky drinkers who were willing to participate in an alcohol prevention intervention in an occupational health setting, and correlates for such willingness.Methods: Risky drinking employees from 22 companies in Norway were identified through an alcohol screening survey. Risky drinkers' (N = 779) willingness to complete a health examination and to be randomized into an alcohol prevention intervention (digital or face-to-face intervention, or control) was recorded by personnel from occupational health services. The proportion of employees who were willing to participate was assessed on 31 potential correlates (sociodemographic, alcohol-related, work-related, and lifestyle/daily activity). Adjusted (multiple logistic regression) analyses were utilized to explore associations between potential correlates and willingness to participate.Results: Altogether, 38.1% of employees were willing to participate in prevention interventions. In the adjusted analysis, only 5 out of 31 potential correlates were significantly associated with willingness to participate. Managers were more than twice as willing to participate than workers (OR = 2.17, p &lt; 0.01). Willing employees had less workplace decision latitude (perceived control over workplace decisions and less possibility of utilizing personal skills in the job) (OR = 0.62, p &lt; 0.05), and were more overcommitted with exorbitant work ambition and need for approval (OR = 1.49, p &lt; 0.05). Willing employees had to some extent less alcohol-related impaired work performance (presenteeism, OR = 0.78, p &lt; 0.05), and they spent less time on care activities (OR = 0.84, p &lt; 0.05).Conclusions: Reaching four out of ten with risky drinking habits for prevention interventions strengthens the rationale for targeting this public health problem in occupational health care settings. In particular, this study suggests the importance of ensuring secure commitment among workers, who were less willing til participate than managers. Nevertheless, tailoring recruitment and implementation strategies based on easily identifiable correlates may be onerous.
Surgical Site Infections Are Associated With Higher Blood Loss and Open Access in General Thoracic Practice
Authors: Aeschbacher Pauline , Nguyen Thanh-Long , Dorn Patrick , Kocher Gregor Jan , Lutz Jon Andri 
Published: June 2021

Background: Surgical site infections (SSIs) are the most costly and second most frequent healthcare-associated infections in the Western world. They are responsible for higher postoperative mortality and morbidity rates and longer hospital stays. The aim of this study is to analyze which factors are associated with SSI in a modern general thoracic practice.Methods: Data were collected from our department's quality database. Consecutive patients operated between January 2014 and December 2018 were included in this retrospective study.Results: A total of 2430 procedures were included. SSIs were reported in 37 cases (1.5%). The majority of operations were video-assisted (64.6%). We observed a shift toward video-assisted thoracic surgery in the subgroup of anatomical resections during the study period (2014: 26.7%, 2018: 69.3%). The multivariate regression analysis showed that blood loss &gt;100 ml (p = 0.029, HR 2.70) and open surgery (p = 0.032, HR 2.37) are independent risk factors for SSI. The latter was higher in open surgery than in video-assisted thoracic procedures (p &lt; 0.001). In the subgroup of anatomical resection, we found the same correlation (p = 0.043). SSIs are also associated with significantly longer mean hospital stays (17.7 vs. 7.8 days, p &lt; 0.001).Conclusion: As SSIs represent higher postoperative morbidity and costs, efforts should be made to maintain their rate as low as possible. In terms of prevention of SSIs, video-assisted thoracic surgery should be favored over open surgery whenever possible.
Analysis of Volatile Molecules Present in the Secretome of the Fungal Pathogen Candida glabrata
Authors: López-Ramos Juan Ernesto , Bautista Elihú , Gutiérrez-Escobedo Guadalupe , Mancilla-Montelongo Gabriela , Castaño Irene , González-Chávez Marco Martín , De Las Peñas Alejandro 
Published: June 2021

Candida albicans, Candida glabrata, Candida parapsilosis and Candida tropicalis are the four most common human fungal pathogens isolated that can cause superficial and invasive infections. It has been shown that specific metabolites present in the secretomes of these fungal pathogens are important for their virulence. C. glabrata is the second most common isolate world-wide and has an innate resistance to azoles, xenobiotics and oxidative stress that allows this fungal pathogen to evade the immune response and persist within the host. Here, we analyzed and compared the C. glabrata secretome with those of C. albicans, C. parapsilosis, C. tropicalis and the non-pathogenic yeast Saccharomyces cerevisiae. In C. glabrata, we identified a different number of metabolites depending on the growth media: 12 in synthetic complete media (SC), 27 in SC-glutamic acid and 23 in rich media (YPD). C. glabrata specific metabolites are 1-dodecene (0.09 ± 0.11%), 2,5-dimethylundecane (1.01 ± 0.19%), 3,7-dimethyldecane (0.14 ± 0.15%), and octadecane (0.4 ± 0.53%). The metabolites that are shared with C. albicans, C. glabrata, C. parapsilosis, C. tropicalis and S. cerevisiae are phenylethanol, which is synthesized from phenylalanine, and eicosane and nonanoic acid (identified as trimethylsilyl ester), which are synthesized from fatty acid metabolism. Phenylethanol is the most abundant metabolite in all fungi tested: 26.36 ± 17.42% (C. glabrata), 46.77 ± 15.58% (C. albicans), 49.76 ± 18.43% (C. tropicalis), 5.72 ± 0.66% (C. parapsilosis.) and 44.58 ± 27.91% (S. cerevisiae). The analysis of C. glabrata’s secretome will allow us to further our understanding of the possible role these metabolites could play in its virulence.
Factors affecting the documentation of spoken safety-netting advice in routine GP consultations: a cross-sectional study
Authors: Edwards Peter J , Bennett-Britton Ian , Ridd Matthew J , Booker Matthew , Barnes Rebecca K 
Published: June 2021

BackgroundPrevious studies have reported how often safety-netting is documented in medical records, but it is not known how this compares with what is verbalised and what factors might influence the consistency of documentation.AimTo compare spoken and documented safety-netting advice and to explore factors associated with documentation.Design and settingA cross-sectional study, using an existing GP consultations archive.MethodObservational coding involving classifying and quantifying medical record entries and comparison with spoken safety-netting advice in 295 video-/audio-recorded consultations. Associations were tested using logistic regression.ResultsTwo-thirds of consultations (192/295) contained spoken safety-netting advice that applied to less than half of the problems assessed (242/516). Only one-third of consultations (94/295) had documented safety-netting advice, which covered 20.3% of problems (105/516). The practice of GPs varied widely, from those that did not document their safety-netting advice to those that nearly always did so (86.7%). GPs were more likely to document their safety-netting advice for new problems (P = 0.030), when only a single problem was discussed in a consultation (P = 0.040), and when they gave specific rather than generic safety-netting advice (P = 0.007). In consultations where multiple problems were assessed (n = 139), the frequency of spoken and documented safety-netting advice decreased the later a problem was assessed.ConclusionGPs frequently do not document the safety-netting advice they have given to patients, which may have medicolegal implications in the event of an untoward incident. GPs should consider how safely they can assess and document more than one problem in a single consultation and this risk should be shared with patients to help manage expectations.
Protagoras et son procès d’impiété : peut-on soutenir une thèse et son contraire ?
Authors: Lenfant Dominique 
Published: June 2021

Nowadays, scepticism prevails about the trial of Protagoras, but the arguments in its favour are not conclusive : the chronology and the nature of the sources require a sharper analysis. In fact, the elaboration of biographical traditions in the Hellenistic period presents too many uncertainties to allow any assurance. One cannot affirm that the trial did or did not take place. Therefore one should not draw general conclusions from this case, as has been regularly done, when an effort has been made to denounce or else to deny the so-called Athenian intolerance. The meaning which modem scholars have given to the case is, in fact, irrelevant, especially when they use concepts such as “intellectual freedom” or “intolerance”.
The first appendix shows that the Aristotelian evidence on the trial of Protagoras is not improbable. The second appendix argues against the inconclusive arguments of sceptical scholars in favour of the historicity of the decree of Diopeithes.
İslâmî Sermaye Piyasası
Authors: ÖZ Ahmet , BADEM Mustafa 
Published: June 2021

İslâmî sermaye piyasaları, hisse senedi veya sukûk gibi yatırım araçlarının ihraç edildiği piyasalardır. Bu yatırım araçlarının vadesi bir yıldan fazladır. Dini hassasiyete sahip olan yatırımcılar uzun vadede birikimlerini değerlendirmek için bu yatırım araçlarından birine yönelirler. Yatırımcı, İslâmî sermaye piyasası araçlarından olan hisse senetlerini veya sukûk türlerinden birisini satın almayı tercih eder. Tercihi doğrultusunda çeşitli finans kurumları devreye girer. Yatırımcı bireysel olarak İslâm hukukuna uyumluluk noktasında doğru tespitler yapamayabilir. Şer’î endeksler, yatırım fonları ve çeşitli finans kurumları yatırımcının en doğru tercihi yapmasına yardımcı olurlar.
Ayrıca İslâm hukukuna uygun yatırım araçları, konvansiyonel ekonomik sistemde, İslâm hukukunun kurallarına uymayan yatırım araçlarına şer’î alternatifler sunar. Ortaya konulan bu alternatifler sayesinde zaman içerisinde, dini hassasiyetlere sahip olan insanların karşısına çıkabilecek iktisadi sıkıntılar engellenmiş olur. Ancak bu yapının İslâmî kurallara uygun olup olmadığının iyi bir şekilde araştırılması gerekir. Eğer yatırımcılar bireysel olarak konuya vâkıf değil ise yatırımlarını çeşitli İslâmî finans kurumları aracılığıyla yapabilir. Böylece dini ilke ve kurallara azami ölçüde bağlı kalmış olurlar.
Efectos sociales y culturales del turismo en las comunidades Roberto Barrios y La Cascada de Palenque, Chiapas, México
Authors: Ramon Hernandez Pedro 
Published: June 2021

El propósito de este trabajo es conocer los efectos sociales y culturales que provoca la actividad turística en las comunidades Roberto Barrios y La cascada, ambas en el municipio de Palenque, Chiapas, México. Esta investigación se desarrolla en dos etapas, la primera es una caracterización de ambas comunidades y sus respectivos atractivos turísticos. La segunda corresponde a la aplicación de una entrevista en profundidad, se platicó ampliamente con 22 personas de un universo de 35, que se seleccionaron con base en el tiempo de vivir en la comunidad, por tener alguna representación social y cultural, y por pertenecer a las dos agrupaciones que operan los dos centros turísticos.
Los resultados muestran que no existen evidencias significativas de los efectos social y cultural derivados de la presencia de turistas nacionales y extranjeros que visitan ambos atractivos. Se observa una disminución en la práctica de temas como: el religioso y algunas actitudes que están siendo adoptadas por los residentes de ambas comunidades, sobre todo jóvenes del sexo masculino. La participación de las mujeres en actividades turísticas es mínima.
A partir de estos resultados, se sugiere trabajar en el diseño de un programa integral orientado a reforzar los valores, las costumbres y tradiciones, sobre todo las de carácter religioso y gastronómico, así como conductas que permitan rescatar las costumbres y rituales de los residentes de generaciones pasadas en ambas comunidades, esto como una forma de conservación y fortalecimiento de las raíces indígenas locales que refuercen los aspectos culturales, particularmente en los jóvenes, pero que también se fortalezca el concepto de comunidad.
Wokół dramaturgicznego debiutu Felicjana Faleńskiego
Authors: Dybizbański Marek 
Published: June 2021

Nigdy niewydany pierwszy ukończony dramat Felicjana Faleńskiego – Smutne dzieje powstania w Dalekarlii z 1867 roku – odpowiada programowym założeniom Victora Hugo, wedle których dzieło sztuki dramatycznej powinno być „przeszłością ożywioną na rzecz teraźniejszości”. Pisany pod wpływem świeżego wspomnienia powstania styczniowego traktuje o zrywie Szwedów przeciwko dominacji Danii w związku państw skandynawskich ustanowionym przez unię kalmarską u schyłku XIV wieku, przedstawia nadużycia Duńczyków i króla Eryka Pomorskiego, bunt szwedzkich możnowładców i mas ludowych pod dowództwem prostego górnika, obalenie króla, zdradę jednego z feudałów, zamach stanu, skrytobójstwo. Akcja została skomponowana według mechanizmów dziejowych znanych z szekspirowskich kronik z przydaniem w losie monarchy calderonowskiego pierwiastka rządów Bożej opatrzności nad światem ziemskiej historii.
Identification Of Physiotherapy Student Fitness At Poltekkes Kemenkes Surakarta
Authors: Handari Herdianty Kusuma , Kusumaningtyas Mei 
Published: June 2021

Background: The convenience provided by technology makes a person tend to reduce physical activity. In a long time it will certainly have an impact on one's fitness. This will also affect adolescents to young adults, where the average circle is students in college. Fitness is very important to support daily activities, without fitness someone will easily experience fatigue. Currently, students tend to do less physical activity because they lie too much or are sedentary as a result of technological advances. As a physiotherapy student who will treat patients later, fitness needs to be maintained since in the college. So far, fitness identification has never been done for students in health institutions, especially in physiotherapy students in the Poltekkes Kemenkes Surakarta, so this study aims to determine the fitness condition of physiotherapy students.
Methods: this research is a descriptive study by measuring 8 fitness components namely flexibility, balance, strength, explosive power, speed, agility, coordination and endurance in 226 physiotherapy students and the data analized descriptively using Ms. Excel.
Results: Based on the measurement results, it was found that flexibility, balance and strength were included in the good category, explosive power, agility and coordination were in the very poor category, speed and endurance were in the excellent category. The physiotherapy student fitness index shows an average value of 3.125, which means that student fitness is included in the fair category.
Conclusion: there is efforts should be made to maintain and improve the fitness of physiotherapy students in the Poltekkes Kemenkes Surakarta.
The Effect Of Breathing Relaxation And Lavender Aromatherapy On Insomnia In The Elderly
Authors: Mahyuvi Tata , Perbawani Dhian Restika , Suwardianto Heru 
Published: June 2021

Background: The elderly experience insomnia in the form of problems with symptoms of sleep disorders in the form of repeated difficulties in sleeping or maintaining sleep even though there is an opportunity to sleep. The objective of research was to analyze the effect of Breathing Relaxation Aromatherapy Combination Lavandula Angustifolia on Insomnia in the Elderly.
Methods: The design was a pre-experiment with approach the one group pretest-posttest design. The research population was elderly insomnia in elderly Posyandu and the sample was 21 peoples. The sampling research was total sampling. Variabel independent was Breathing Relaxation combination with lavender aromatherapy is relaxation using breathing techniques slowly and deeply, variabel dependen was insomnia level. Statistic test use Wilcoxon Signed Ranks Test
Results: The results showed that The Wilcoxon Signed Ranks Test ρ value = 0,000, H1 is accepted, meaning that there is an effect of the Breathing Relaxation and lavender aromatherapy on insomnia in the elderly. The combination of Breathing Relaxation and lavender aromatherapy increases the relaxation response in the elderly.
Conclusion: Effect of Breathing Relaxation combination of lavender aromatherapy (Lavandula angustifolia) is more effective in reducing insomnia levels in the elderly and is highly recommended and safe for the elderly)