bluuebunny/crossref_metadata_2025_split huggingface dataset:
Business Vulnerability and Credit Access for Agriculture-Based Micro and Small Women Entrepreneurs
Authors: Martokoesoemo Dewi Ratna Sjari , Sinaga Bonar M. , Kusnadi Nunung , Syaukat Yusman 
Published: March 2021

Micro and Small Industries (MSIs) constitute the largest share of Indonesia’s manufacturing sector and play an important role in providing employment opportunities and value-added creation. However, their business sustainability and scaling up are often hindered by various factors, one of which is access to credit. The subsidized loan scheme provided by the government, namely People’s Business Credit (KUR), appears to be insufficiently attractive to entrepreneurs, especially to Micro and Small Women Entrepreneurs (MSWEs). Employing a logit regression method and utilizing the BPS-Statistics Indonesia’s 2015 MSI survey data, this study aims to investigate factors affecting MSWEs’ decision to apply for bank loans and factors contributing to the approval of their credit applications by banks. The results show that MSWEs have low participation in credit borrowing, partially due to business vulnerability and self-rationing attitude, while credit application rejection is caused mainly by banks’ conservative approach to MSWEs. Practical implications of the findings are discussed.
A Decomposition Analysis of Fertility: Evidence from DKI Jakarta and East Nusa Tenggara
Authors: Mangunsong Farma 
Published: March 2021

Fertility control has been one of the priorities of development in Indonesia. However, the 2000 and 2010 population censuses showed an increase in fertility indicators. To identify the sources of increased fertility in developed and less developed areas, DKI Jakarta and East Nusa Tenggara Provinces were selected for comparison. Using 2000 and 2010 census data, the decomposition analysis shows that the increase in Total Fertility Rate (TFR) of DKI Jakarta was dominated by the increase in nuptiality rate, while the increase in TFR of East Nusa Tenggara was mainly caused by the increase in Marital Fertility Rate (MFR). The highest increase in the proportion of married women in DKI Jakarta occurs in the age group of 15-19 years old, followed by the age group of 20–24 years old. The increase in MFR in East Nusa Tenggara occurs in nearly all age groups, particularly in the age groups of 30–34 and 35–39 years old. Identifying the sources of the increase in TFR is important for population policy to support population growth control, fertility reduction, and human resource quality improvement. The main suggestions based on the findings are the promotion of higher educational level and the benefits of postponing marriage among the younger age groups in DKI Jakarta as well as the use of contraceptive methods to control birth rate in East Nusa Tenggara.
The Role of Banking Services in Determining the Destination Countries for Indonesia’s Non-Oil and Gas Export
Authors: Satriani Rini , Machmud T. M. Zakir 
Published: March 2021

This study aims to examine whether the risk factor and banking services play a significant role in determining not only the export performance of a country but also the pattern of export destination markets, with the reference to the case of Indonesia. These two indicators are interrelated because the risk factor in export transactions can be mitigated by banking sector. Using the data of export Letter of Credits (LCs) for non-oil and gas exports of Indonesia as a banking instrument to mitigate special risk transactions to 102 export destination countries as well as a panel data methodology for the 2011–2018 period, this study discovers that the risk of export destination countries affects the decline in non-oil and gas exports of Indonesia to the alleged high-risk countries that are non-traditional export markets of Indonesia by 8.34%. In contrast, the LCs only significantly affect the increase in non-oil and gas exports of Indonesia to the lowand medium-risk countries by 0.024–0.029%, most of which are traditional export markets of Indonesia. It implies that banking sector in general does not have the appetite for providing financing for Indonesian exporters attempting to penetrate non-traditional export markets. This result underlines that commercial banks in Indonesia have a significant role in shaping the pattern of destination countries for Indonesian export. Consequently, government intervention is essentially needed by assuming or sharing part of the risk with state banks supposing the government continues to expect exporters to be able to penetrate into the non-traditional countries.
ITGB6 may promote proliferation and invasion in pancreatic cancer
Authors: Zhong Chao , Li Zhi-Xi , Yang Ling-Jing , Wu Gang , Xiang Bo , Wang Yu-Lan , Zhou Qing 
Published: March 2021

IntroductionThe ITGB6 gene encoding a protein that can regulate the integrin v6 heterodimer protein expression in different status was shown to play an important role in multiple human cancers, such as brain cancer, colon cancer and oral cancer, and is related to clinical progression. This study aims to explore the function and the mechanism of the ITGB6 gene or protein in pancreatic cancer.Material and methodsWe examined the expression of ITGB6 in pancreatic cancer using immunohistochemistry and analyzed the relationship between the expression of ITGB6 and the clinicopathologic features in pancreatic cancer patients. In addition, a bioinformatic method was used to analyze the ITGB6 mRNA level in pancreatic tumor tissues compared with normal pancreatic tissues and to analyze the correlation between high KIF23 expression and prognosis in pancreatic cancer patients. Moreover, colony formation assay, MTT assay, cell scratch, cell invasion and western blot assays in vitro and a xenograft mouse model in vivo were performed to analyze the effect of KIF23 on proliferation and invasion of pancreatic cancer cells.ResultsIncreased expression of ITGB6 was significantly correlated with poor clinical outcome in both our clinical data and TCGA data of pancreatic cancer. Furthermore, functional assays revealed that ITGB6 knockdown in vivo and in vitro might inhibit cancer cell proliferation and the ability of invasion or migration.ConclusionsOur data suggest that ITGB6 is associated with pancreatic cancer malignant progression. Hence, ITGB6 may serve as a potential target of pancreatic cancer for future research, and further study is needed.
Security in Quantum Computing
Authors: Petrache Ana Lavinia , Suciu George 
Published: March 2021

Quantum key distribution will bring more confidentiality and privacy of communication in the future ICT world and will solve the eavesdropping issue. Domains regarded are e-government, e-commerce, e-health, transmission of biometric data, intelligent transport systems and more. So far, quantum researches focus on using properties of the qubit to bring improvements in technologies from our days. The purpose of this paper is to describe the quantum encryption methods. These methods can bring more efficiency of security in existing communications. In this matter, many encryption architectures have been proposed. As an example, the QKD architecture is presented in this paper.
The use of specialized products of children’s dietary medical nutrition for children with organic aciduria (acidemia)
Authors: Семенова Н.А. , Шестопалова Е.А. , Лязина Л.В. , Куцев С.И. 
Published: March 2021

Целью данного исследования было изучить эффективность и переносимость специализированных продуктов детского диетического лечебного питания у детей с наследственными нарушениями обмена аминокислот с рождения до трех лет. Проведено открытое, многоцентровое, проспективное, неконтролируемое исследование. В исследование включены 8 пациентов с установленным диагнозом в возрасте от рождения до 2 лет 11 месяцев. Пациенты были распределены на группы в зависимости от диагноза и вида исследуемого продукта (ИП). Оценка эффективности проводилась в соответствии с принципами надлежащей клинической практики, на основании полученных клинических и лабораторных данных. На протяжении всего исследования все пациенты успешно принимали ИП. Диспепсических явлений, аллергических реакций, ухудшения соматического и неврологического статуса не зарегистрировано ни в одном случае. На фоне лечения зафиксированы оптимальные уровни нейротоксичных метаболитов в крови и моче. Показана высокая клиническая эффективность ИП у детей с наследственными нарушениями обмена аминокислот с рождения до трех лет.
To assess the efficacy, safety and tolerability of the products specialized children's dietary nutritional therapy in children with Inherited disorders of amino acid metabolism from birth to three years. 8 children from birth to 2y 11m with verified diagnoses were enrolled in this open-label multicenter prospective non-controlled study. Patients were separated to the groups depending on diagnose and nutritional treatment products. Clinical efficacy of the products was assessed according to the Good Clinical Practice guidelines based on clinical and laboratory tests. All patients taken nutritional treatment products throughout the study. No dyspepsia, allergic reactions, impairment of somatic and neurological status were reported. After the treatment, levels of neurotoxic metabolites in the blood and urine were optimal. Nutritional therapy is highly effective in children with Inherited disorders of amino acid metabolism from birth to three years.
Press conference «Nutritional care in COVID-19»
Authors: Гируцкая Е.О. 
Published: March 2021

В феврале 2021 г. в онлайн-режиме состоялась пресс-конференция «Лечебное питание при COVID-19». На ней рассказывалось о результатах проспективного открытого сравнительного наблюдательного исследования по оценке влияния смеси специализированного питания на способность пациентов с COVID-19 к восстановлению здоровья. Исследование проводилось под эгидой Национальной ассоциации клинического питания и метаболизма на базе 5 центров в Москве, Санкт-Петербурге, Екатеринбурге и Омске. Согласно его результатам, к стандартным методам ведения больных стоит добавить нутритивную поддержку: в специализированном питании нуждаются около 60-70% пациентов c COVID-19.
In February 2021, an online press conference entitled «Nutritional care in COVID-19» was held. It presented the results of a prospective, open-label, comparative observational study evaluating the effect of specialty food mix on the ability of COVID-19 patients to recover. The study was conducted under the auspices of the National Association for Clinical Nutrition and Metabolism at 5 centers in Moscow, St. Petersburg, Yekaterinburg and Omsk. According to its results, nutritional support should be added to the standard methods of patient management: about 60-70% of patients with COVID-19 need specialized nutrition.
Retrieval of stratospheric aerosol size distribution parameters using satellite solar occultation measurements at three wavelengths
Authors: Wrana Felix , von Savigny Christian , Zalach Jacob , Thomason Larry W. 
Published: March 2021

Abstract. In this work, a novel approach for the determination of the particle size distribution (PSD) parameters of stratospheric sulfate aerosols is presented. For this, ratios of extinction coefficients obtained from SAGE III/ISS (Stratospheric Aerosol and Gas Experiment III on the International Space Station) solar occultation measurements at 449, 756 and 1544 nm were used to retrieve the mode width and median radius of a size distribution assumed to be monomodal lognormal. The estimated errors at the peak of the stratospheric aerosol layer, on average, lie between 20 % and 25 % for the median radius and 5 % and 7 % for the mode width. The results are consistent in magnitude with other retrieval results from the literature, but a robust comparison is difficult, mainly because of differences in temporal and spatial coverage. Other quantities like number density and effective radius were also calculated. A major advantage of the described method over other retrieval techniques is that both the median radius and the mode width can be retrieved simultaneously, without having to assume one of them. This is possible due to the broad wavelength spectrum covered by the SAGE III/ISS measurements. Also, the presented method – being based on the analysis of three wavelengths – allows unique solutions for the retrieval of PSD parameters for almost all of the observed extinction spectra, which is not the case when using only two spectral channels. In addition, the extinction coefficients from SAGE III/ISS solar occultation measurements, on which the retrieval is based, are calculated without a priori assumptions about the PSD. For those reasons, the data produced with the presented retrieval technique may be a valuable contribution for a better understanding of the variability of stratospheric aerosol size distributions, e.g. after volcanic eruptions. While this study focuses on describing the retrieval method, and a future study will discuss the PSD parameter data set produced in depth, some exemplary results for background conditions in June 2017 are shown.
Atmospheric carbon dioxide variations across the middle Miocene climate transition
Authors: Raitzsch Markus , Bijma Jelle , Bickert Torsten , Schulz Michael , Holbourn Ann , Kučera Michal 
Published: March 2021

Abstract. The middle Miocene climate transition ∼ 14 Ma marks a fundamental step towards the current “ice-house” climate, with
a ∼ 1 ‰ δ18O increase and a
∼ 1 ‰ transient δ13C rise in
the deep ocean, indicating rapid expansion of the East Antarctic Ice Sheet
associated with a change in the operation of the global carbon cycle. The
variation of atmospheric CO2 across the carbon-cycle perturbation has
been intensely debated as proxy records of pCO2 for this time interval
are sparse and partly contradictory. Using boron isotopes (δ11B) in planktonic foraminifers from Ocean Drilling Program (ODP) Site 1092 in the South
Atlantic, we show that long-term pCO2 varied at 402 kyr periodicity
between ∼ 14.3 and 13.2 Ma and follows the global δ13C variation remarkably well. This suggests a close link to
precessional insolation forcing modulated by eccentricity, which governs the
monsoon and hence weathering intensity, with enhanced weathering and
decreasing pCO2 at high eccentricity and vice versa. The ∼ 50 kyr lag of δ13C and pCO2 behind eccentricity in our
records may be related to the slow response of weathering to orbital
forcing. A pCO2 drop of ∼ 200 µatm before 13.9 Ma
may have facilitated the inception of ice-sheet expansion on Antarctica,
which accentuated monsoon-driven carbon cycle changes through a major
sea-level fall, invigorated deep-water ventilation, and shelf-to-basin shift
of carbonate burial. The temporary rise in pCO2 following Antarctic
glaciation would have acted as a negative feedback on the progressing
glaciation and helped to stabilize the climate system on its way to the
late Cenozoic ice-house world.
Seismic monitoring of urban activity in Barcelona during the COVID-19 lockdown
Authors: Diaz Jordi , Ruiz Mario , Jara José-Antonio 
Published: March 2021

Abstract. During the COVID-19 pandemic
lockdown, the city of Barcelona was covered by a dense seismic network consisting of up to 19 seismic sensors.
This network has provided an excellent tool to investigate in detail the
background seismic-noise variations associated with the lockdown measures.
Permanent stations facilitate comparing the seismic noise recorded during
the lockdown quieting with long-term variations due to holiday periods. On
the other hand, the data acquired by the dense network show the differences
between sites located near industrial areas, transportation hubs or
residential areas. The results confirm that the quieting of human activity
during lockdown has resulted in a reduction in seismic vibrations in the
2–20 Hz band that is clearly higher than during holiday seasons. This effect is
observed throughout the city, but only those stations not affected by very
proximal sources of vibration (construction sites, industries) are clearly
correlated with the level of activity denoted by other indicators. Our
contribution demonstrates that seismic amplitude variations can be used as a
proxy for human activity in urban environments, providing details similar to
those offered by other mobility indicators.
Efecto del suplemento de ácidos grasos omega 3 sobre el nivel de memoria en pacientes con alzhéimer leve del Hospital Víctor Lazarte Echegaray- EsSalud, Trujillo 2015
Authors: IIDENUT Renut , Tapia LLorca Litta Del Carmen 
Published: March 2021

Objetivo. El presente estudio tuvo como objetivo determinar el efecto del suplemento de ácidos grasos omega 3 sobre el nivel de memoria en pacientes con Alzheimer leve del Hospital Víctor Lazarte Echegaray- EsSalud, Trujillo 2015. Sujetos y métodos. La investigación fue un estudio experimental de serie cronológica, que evaluó a 20 pacientes con Alzheimer leve, entre 40 a 65 años, distribuidos en dos grupos: Grupo experimental (GE) con 10 pacientes tratados con omega-3; 720 mg /día y el grupo control (GO) con 10 pacientes suplementados con placebo durante el periodo de 16 semanas, con una observación basal y observaciones posteriores cada 4 semanas. Resultados. Ambos grupos fueron evaluados mediante el Test de alteración de memoria (TAM) en la semana O1, el grupo control y el grupo experimental presentaron un nivel de memoria deficiente (100%), En la comparación entre el grupo experimental vs control, en la semana 08 se encontró una mejoría altamente significativa (p<0,01) en la memoria total y la memoria remota semántica. Finalmente en la semana 16 se halló una mejoría altamente significativa (p<0,01) en la memoria inmediata, memoria remota semántica, memoria total y el tiempo de respuesta y una mejoría significativa (p<0,05) en la memoria de evocación libre y de evocación con pistas, todo esto a favor del grupo experimental tratado con omega 3. Conclusión. La suplementación de ácidos grasos Omega-3 presenta un efecto positivo en la mejora del nivel de memoria en pacientes con Alzheimer leve, pero no obtiene el puntaje requerido para ser considerado en un nivel adecuado.
Capacidades adquiridas: Al finalizar el artículo, los lectores podrán:a. Describir los cambios fisiopatológicos de la enfermedad de Alzheimer según su estadiob. Describir el impacto de la suplementación de omega 3 en el estadio leve de la enfermedad de Alzheimer.c. Proponer esquemas de suplementación profiláctica en el estadio 1 de la enfermedad de Alzheimer
Aceptabilidad y evaluación proteica de galletas integrales elaboradas con harina de cañihua (chenopodium pallidicaule), lactosuero y salvado de trigo.
Authors: IIDENUT Renut , Juárez Vilca Sandra , Quispe Avilés Milagros 
Published: March 2021

Objetivo. Evaluar la aceptabilidad y la calidad proteica de galletas integrales elaboradas con harina de cañihua (Chenopodium pallidicaule), lactosuero y salvado de trigo. Materiales y métodos. El estudio fue prospectivo experimental. Se elaboraron 3 tipos de galletas, la galleta “A” (15% de harina de cañihua), la galleta “B” (30 % de harina de cañihua) y la galleta “C” (50% de harina de cañihua), adicionando a las tres galletas 17 % de lactosuero y 7% de salvado de trigo. Se probó la aceptabilidad de las galletas; aquella de mayor aceptación fue sometida a pruebas de calidad proteica en animales de experimentación: cómputo aminoacídico, Relación de Eficiencia Proteica (PER), Retención Neta de Proteína (NPR), Utilización Neta de Proteínas (NPU) y Digestibilidad Verdadera (DV), respectivamente. Resultados. La galleta “C” tuvo la mayor aceptabilidad. Respecto al Cómputo Aminoacídico, la galleta “C” no presentó aminoácidos limitantes; su PER fue de 1,74, su NPR fue de 1 ,71, el NPU fue de 74,25 y la DV tuvo como valor 71 ,1 siendo estos valores menores que el grupo control: de PER 1,9, NPR 1,8, NPU 83,22 y DV 79,9; respectivamente. Conclusión. La galleta con una sustitución de 50% de harina de cañihua fue la de mayor aceptación y de mejor valor nutricional.
Capacidades adquiridas: Al finalizar el artículo, los lectores podrán:a. Describir las características de las pruebas para valorar la calidad proteicab. Justificar las características nutricionales de la proteína de la harina elaborada a base de cañihua.c. Sustentar el empleo de harina de cañihua en la formulación de alimentos de consumo humano.
Impacto de la educación nutricional en el manejo del sobrepeso y obesidad
Authors: IIDENUT Renut , Revilla María Elena 
Published: March 2021

Los adultos pasan cerca del 60% del día en su centro laboral, siendo este un escenario importante para realizar una intervención nutricional que contribuya a combatir el incremento del sobrepeso y la obesidad; así como, sus consecuencias en la salud, como son diabetes mellitus tipo 2, enfermedad cardiovascular, y en el trabajo, como, ausentismo, presentismo y menor productividad. El ambiente laboral, en este sentido, permite desarrollar educación nutricional mediante el diseño intervenciones dirigidas relacionadas con la ingesta de alimentos, rutina y espacio compartido. Las intervenciones han demostrado tener una mejora significativa en los hábitos alimentarios disminuyendo el consumo de total de grasa dietaria e incrementando el consumo diario de frutas y verduras; como también en la pérdida de peso disminuyendo de 0.2 kg. a 6.4 kg. en un periodo de seguimiento de 2 a 18 meses. Además, los estudios refieren que las intervenciones más efectivas han incluido estrategias de promoción de salud como, educación nutricional, utilizando tecnología y la participación de los colaboradores, generando compromiso con los objetivos del programa.
Consenso 2: Tamizaje Nutricional CONSENSO 2: TAMIZAJE NUTRICIONAL
Authors: IIDENUT Renut , Cruz Robinson , Herrera Teresa , Windmueller Andrea , Yncio Carmen , López Rosana , Yucra Marlen , Mendez Carolina , Pérez Martha , Maffare Vadlimir , Alas Raquel , Mencomo Myrna , Maza Claudia , Franco Raquel , Nava Edna 
Published: March 2021

Los miembros y coordinadores de los capítulos nacionales integrantes del Comité Internacional para la Elaboración de Consensos y Estandarización en Nutriología (CIENUT), después de un proceso profundo de discusión y análisis, declaramos lo siguiente:

La detección precoz de problemas nutricionales, que pudiesen afectar el estado de salud de las personas o reagudizar una patología, es una parte fundamental del proceso de atención nutricional en todo nivel de atención. Por diversas circunstancias, existe una brecha significativamente grande de atención nutricional no cubierta por parte de profesionales de la nutrición, lo cual se ve reflejado en tasas elevadas de morbi-mortalidad que acarrean daños al paciente y gastos innecesarios a las instituciones, aspectos que pudieron evitarse oportunamente.
En este contexto, hemos elaborado el Consenso 2 denominado Tamizaje Nutricional; este consenso busca fijar los criterios técnicos y científicos, por los cuales se logre lo siguiente:

La implementación de herramientas de tamizaje nutricional en todo nivel de atención tomando en cuenta tanto su validez interna como externa.
La reglamentación básica necesaria para que sea el profesional de nutrición quién, en principio, sea el encargado de llevar a cabo la aplicación de herramientas de tamizaje y que, en caso no pudiese hacerlo por escasez de recurso humano, sea otro profesional de la salud debidamente capacitado tanto en la ejecución como en la importancia de los resultados.

Invocamos, además, a todas las instituciones que brindan atención nutricional suscriban este consenso y hagan todo lo necesario para que pueda implementarse en la forma más rápida posible.

Firmado el 14 de setiembre de 2019 en Lima, Perú.