bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Algae Society BioArt Design Lab: Exploring Multispecies Entanglements and Making Kin with Algae
Authors: Harrower Juniper , Felice Gene , Parker Jennifer , Espinel José Carlos , Harris David , Hillary Fiona , Ribeaux Tiare 
Published: December 2021

Abstract
The Algae Society BioArt Design Lab is a global collective of interdisciplinary researchers working together with algae as nonhuman international research partners. As a collaborative group of artists, scientists, and scholars, they experiment and coproduce with algae, seeking to highlight complex human interdependence and kinship with algal beings. Here the founding members introduce the Algae Society and share a collective collage of their evolving artistic works while reflecting on each researcher’s process, materiality, and aesthetic considerations. With these works, they endeavor to shift our perspectives from human-centric exceptionalism to greater appreciation and cultural reframing of our responsibility as participants in multispecies worlding.
Just an artifact? The concordance between peer review and bibliometrics in economics and statistics in the Italian research assessment exercise
Authors: Baccini Alberto , De Nicolao Giuseppe 
Published: December 2021

Abstract
During the Italian research assessment exercise (2004–2010), the governmental agency (ANVUR) in charge of its realization performed an experiment on the concordance between peer review and bibliometrics at an individual article level. The computed concordances were at most weak for science, technology, engineering, and mathematics. The only exception was the moderate concordance found for the area of economics and statistics. In this paper, the disclosed raw data of the experiment are used to shed light on the anomalous results obtained for economics and statistics. In particular, the data permit us to document that the protocol of the experiment adopted for economics and statistics was different from the one used in the other areas. Indeed, in economics and statistics the same group of scholars developed the bibliometric ranking of journals for evaluating articles, managing peer reviews and forming the consensus groups for deciding the final scores of articles after having received the referee’s reports. This paper shows that the highest level of concordance in economics and statistics was an artifact mainly due to the role played by consensus groups in boosting the agreement between bibliometrics and peer review.
Researching women and men 1996–2020: Is androcentrism still dominant?
Authors: Thelwall Mike , Abdullah Abrizah , Fairclough Ruth 
Published: December 2021

Abstract
This article assesses the balance of research concerning women and men over the past quarter century using the crude heuristic of counting Scopus-indexed journal articles relating to women or men, as suggested by their titles or abstracts. A manual checking procedure together with a word-based heuristic was used to identify whether an article related to women or men. The heuristic includes both explicit mentions of women and men, implicit mentions, and a set of gender-focused health issues and medical terminology. Based on the results, more published articles now relate to women than to men. Moreover, more than twice as many articles relate exclusively to women than exclusively to men, with the ratio increasing from 2.16 to 1 in 1996 to 2.25 to 1 in 2020. Monogender articles mostly addressed primarily female health issues (maternity, breast cancer, cervical cancer) with fewer about primarily male health issues (testicular cancer, pancreatic cancer, health needs of men who have sex with men). Some articles also explicitly addressed gender inequality, such as empowering women entrepreneurs. The findings suggest that the androcentrism of early science has eroded in terms of research topics. This apparent progress should be encouraging for women researchers and society.
Quasi-Idealized Numerical Simulations of Processes Involved in Orogenic Convection Initiation over the Sierras de Córdoba
Authors: Singh Itinderjot , Nesbitt Stephen W. , Davis Christopher A. 
Published: December 2021

Abstract
The Sierras de Córdoba (SDC) range in Argentina is a hotspot of deep moist convection initiation (CI). Radar climatology indicates that 44% of daytime CI events that occur near the SDC in spring and summer seasons and that are not associated with the passage of a cold front or an outflow boundary involve a northerly low-level jet (LLJ), and these events tend to preferentially occur over the southeast quadrant of the main ridge of the SDC. To investigate the physical mechanisms acting to cause CI, idealized convection-permitting numerical simulations with a horizontal grid spacing of 1 km were conducted using Cloud Model 1 (CM1). The sounding used for initializing the model featured a strong northerly LLJ, with synoptic conditions resembling those in a previously postulated conceptual model of CI over the region, making it a canonical case study. Differential heating of the mountain caused by solar insolation in conjunction with the low-level northerly flow sets up a convergence line on the eastern slopes of the SDC. The southern portion of this line experiences significant reduction in convective inhibition, and CI occurs over the SDC southeast quadrant. The simulated storm soon acquires supercellular characteristics, as observed. Additional simulations with varying LLJ strength also show CI over the southeast quadrant. A simulation without background flow generated convergence over the ridgeline, with widespread CI across the entire ridgeline. A simulation with mid- and upper-tropospheric westerlies removed indicates that CI is minimally influenced by gravity waves. We conclude that the low-level jet is sufficient to focus convection initiation over the southeast quadrant of the ridge.
The Mesoscale Response to Global Warming over the Pacific Northwest Evaluated Using a Regional Climate Model Ensemble
Authors: Mass Clifford F. , Salathé Eric P , Steed Richard , Baars Jeffrey 
Published: December 2021

AbstractThis paper describes the downscaling of an ensemble of 12 general circulation models (GCMs) using the Weather Research and Forecasting (WRF) Model at 12-km grid spacing over the period 1970–2099, examining the mesoscale impacts of global warming as well as the uncertainties in its mesoscale expression. The RCP8.5 emissions scenario was used to drive both global and regional climate models. The regional climate modeling system reduced bias and improved realism for a historical period, in contrast to substantial errors for the GCM simulations driven by lack of resolution. The regional climate ensemble indicated several mesoscale responses to global warming that were not apparent in the global model simulations, such as enhanced continental interior warming during both winter and summer as well as increasing winter precipitation trends over the windward slopes of regional terrain, with declining trends to the lee of major barriers. During summer there is general drying, except to the east of the Cascades. The 1 April snowpack declines are large over the lower-to-middle slopes of regional terrain, with small snowpack increases over the lower elevations of the interior. Snow-albedo feedbacks are very different between GCM and RCM projections, with the GCMs producing large, unphysical areas of snowpack loss and enhanced warming. Daily average winds change little under global warming, but maximum easterly winds decline modestly, driven by a preferential sea level pressure decline over the continental interior. Although temperatures warm continuously over the domain after approximately 2010, with slight acceleration over time, occurrences of temperature extremes increase rapidly during the second half of the twenty-first century.Significance StatementThis paper provides a unique high-resolution view of projected climate change over the Pacific Northwest and does so using an ensemble of regional climate models, affording a look at the uncertainties in local impacts of global warming. The paper examines regional meteorological processes influenced by global warming and provides guidance for adaptation and preparation.
Money and Household Consumption Expenditure in Developing Asia: Some Panel ARDL Evidence
Authors: Mahanty Ghanashyama , Rout Himanshu Sekhar , Mishra Swayam Prava 
Published: December 2021

The role of money in influencing real economic activities has been a long-standing debate in macroeconomics. As per the Keynesian theory, household consumption expenditure plays a significant role in promoting economic growth. Given the rapid consumption-led growth pattern in the emerging Asia Pacific region, in this article, we attempt to assess the role of money in influencing household consumption expenditure, which propels economic growth. We employ a panel data set from 2005–2018 for 10 emerging Asian economies, covering Bangladesh, Cambodia, India, Indonesia, Malaysia, Pakistan, Philippines, Sri Lanka, Thailand and Vietnam. Given the region’s heterogeneous nature, we employ a variant of the popular St Louise equation model with autoregressive distributed lag model (ARDL) panel framework based on pooled mean group (PMG) and dynamic fixed effect (DFE) models developed by Pesaran and Shin to study the underlying relationships. Both PMG and DFE models suggest a strong positive relationship between money and household consumption expenditure both in the long run and short run. After allowing for control variables such as government final consumption expenditure and interest rate, the relationships continue to hold steady. Further, the relationship holds true across both narrow (M1) and broad money (M3) measures. The government final consumption expenditure and interest rates do not have influence on household consumption expenditure in the long run, but they have an influence in the short run. JEL Codes: C23, O16, O47, E51, E31, E21
Economic Growth and Electricity Consumption in India: An Econometric Analysis
Authors: Aneja Ranjan , Mathpal Megha 
Published: December 2021

The purpose of this study is to analyse the long-run causal relationship among the per capita electricity consumption ( PCEC) and per capita gross domestic product ( PCGDP), urban population ( UP) and employment ( EMP) pattern in India over the period of 1991–2018. To analyse the long-run association Johansen co-integration test has been used. The results of the Granger-causality test imply that there exists a bidirectional causal relationship between the PCEC and PCGDP whereas there exist unidirectional causality from EMP and UP to PCGDP. Jel Codes: L52, C53, P1
Processing Adipose Tissue to Make it More Stable When Used for Refilling: A Morphologic and Immunohistochemistry Evaluation
Authors: Sabbatini Maurizio , Faruggio Serena , Verna Giovanni , Magnelli Valeria , Dondero Francesco , Boldorini Renzo , Cannas Mario , Grossini Elena 
Published: December 2021

Breast reconstruction has gained from lipofilling the possibility to recover the aesthetic outcome of anatomical profile in a more natural appearance. However, until today, the long-term graft survival remains unpredictable, and sometimes it does not guarantee a well-adequate aesthetic result. In the present work, the morphological changes, occurring in fat mass used for refilling, harvested by the Coleman’s procedure or through the washing/fragmenting procedure were analysed. Adipocyte size; immunohistochemistry against CD8, CD31, CD68 and M2-type macrophages and catalase enzyme, were analysed in vitro on fat mass cultured for 4 weeks. Our observation reveals an increase of connective tissue around the mass and a high number of immune cells occurrence in fat mass harvested by the Coleman’s procedure. Instead, the washing/fragmented procedure would reduce the number of immune cells within the fat mass, increase the size of adipocytes, and cause a wider presence of active vessels profile and greater catalase expression. We hypothesize that the fat mass processed by the Coleman’s procedure would remain more reactive due to a higher number of immune and macrophages cells, prone to develop cystic formation, leading to a suboptimal integration in the recipient site. On the other hand, the conditions more prone to realize an optimal integration would occur in the fat mass processed by the washing/fragmenting procedure: a reduced number of immune cells, low amount of connective tissue, presence of larger adipocytes. Follow-up monitoring did support our conclusion, as we observed a reduction of re-intervention for refilling procedure in patients treated with the washing/fragmenting procedure.
Selection of the optimal first ear for sequential bilateral cochlear implantation in children
Authors: Kim Hantai , Ha Jungho , Gil Eun Sol , Jang Jeong Hun , Park Hun Yi , Choung Yun-Hoon 
Published: December 2021

Objectives When there is a difference in hearing on both ears, where to perform the first cochlear implantation (CI) becomes an important issue. The purpose of the study was to evaluate which ear should be chosen for the first implantation in sequential bilateral CI with a long inter-implant period. Methods The study population consisted of 34 severe-to-profound sensorineural hearing loss pediatrics with the inter-implant period of ≥3 years between the first CI (CI-1) and the second CI (CI-2) before the age of 19 (mean of inter-implant period: 7.1-year). The patients were classified into Group A (CI-1 was performed on the ear with better hearing), Group B (CI-1 on the ear with worse hearing), or Group C (symmetrical hearing in both ears). Speech intelligibility test results were compared between the groups. Results The monosyllabic word scores of CI-1 were excellent in Groups A (91.7±7.9%) and B (92.5±3.6%) but slightly lower in Group C (85.7±14.9%) before the second implantation ( P = .487). At 3 years after the second implantation, all groups demonstrated excellent scores in the bilateral CI condition (95.9±3.0% in Group A; 99.1±.8% in Group B; 97.5±2.9% in Group C, P = .600). However, when the patients were tested in using CI-2 only in Groups A and B after using bilateral CI for 3 years, the scores were inconsistent in Group A (79.6±23.9%; range: 22.2-94.4%), while those were higher and more constant in Group B (92.9±4.8%; 86.8-100.0%). Conclusions The first CI is strongly recommended to perform on a worse hearing ear if they had different hearing levels between ears. Even with the first CI on a worse hearing ear, its performance never deteriorates. In addition, if they receive the second CI several years later, it will be likely that the second one functions better.
Combining flanged intrascleral IOL fixation with Glaucoma Surgery: Initial experience
Authors: Pathak-Ray Vanita , Bansal Aashish K , Malhotra Varun 
Published: December 2021

Purpose To report the initial clinical outcomes of combining glaucoma surgery with flanged intrascleral intraocular lens (F-SFIOL) fixation as a single stage procedure. Methods Retrospective, non-comparative case-series of eyes which underwent combined surgery for glaucoma with F-SFIOL and had at least 6-months of follow-up. A fellowship-trained senior glaucoma surgeon managed all the cases. Results Twelve-eyes of 10 glaucoma patients (8 males, 2 females) underwent F-SFIOL; only 8 of these eyes were combined with a glaucoma procedure. Mean age of patients was 55.1 ± 16.1 years (95%CI [44.4,73.2], median 61 years) and were followed-up for a mean of 21.0 ± 9.5 months, 95% CI [13.1,28.9], median 18 months. F-SFIOL was combined with trabeculectomy ± Mitomycin C in 4 eyes, Ahmed Glaucoma Valve in 3 eyes and needling of a pre-existing bleb in 1. Each eye had controlled intraocular pressure (IOP) at last follow-up (pre-procedure 29.1 ± 13.4 mmHg, 95% CI [17.9, 40.3], median 27 mmHg to 14.5 ± 3.2 mmHg, 95% CI [11.8, 17.1], median 13 mmHg, p = 0.006) and decreased need for number of anti-glaucoma medication (AGM) (pre-procedure 3.7 ± 1.1, 95% CI [2.8,4.6], median 4 to 0.7 ± 0.7, 95% CI [0.1,1.3] median 1, p < 0.001). In all the eyes, best corrected visual acuity (BCVA) was either stable or improved; only 1 eye had astigmatism worse than that pre-existing. In 1 eye IOL was explanted, with an additional procedure to control IOP. No serious long-term complications occurred in any subject. Conclusion The initial experience of single-stage F-SFIOL along with glaucoma surgery, both being performed by the same anterior-segment surgeon, is promising, thereby avoiding the cost, specialised skill, and potential complications of a posterior approach. Glaucoma surgery combined with and adapted to suture-less, flap-less, glue-less intra-scleral IOL fixation is hitherto unreported.
Recurrence of Breast Cancer After Primary Treatment: A Matched Comparison Study of Disease-Free Survival in Women Who Do and Do Not Receive Adjunctive Naturopathic Oncology Care
Authors: Standish L. J. , Sweet E. , Kim Eunjung , Dowd F. , McLaughlin Ryan , Chiang P. , Dale L. , Gaul M. , Andersen M. R. 
Published: December 2021

Purpose: To compare disease free survival experienced by women who received usual oncologic care compared to a cohort of women who received naturopathic oncology care in addition to usual care. Methods: Women with breast cancer who received naturopathic oncology (NO) care in Western Washington State (WA) (N = 176) were recruited to a prospective study of clinical health-related quality of life outcomes and then matched to women who received usual care (UC) only (N = 334). Results: Among 510 women with breast cancer stages 1 to 3, a total of 50 women (10%) experienced a disease-free survival (DFS) ending event within the observation period; 23 (6.8% of those in the UC cohort, and 27 (15.3% of those in the NO cohort ( P < .05). Although, women in the 2 cohorts received similar surgical, chemotherapy, and radiation treatment, women with breast cancer who received naturopathic oncology adjunctive care were less likely to use anti-estrogen therapy, and experienced poorer DFS (logrank test, P < .05). However, differences in DFS could not be shown to be due to cohort differences in anti-estrogen therapy, baseline HRQOL, or naturopathic oncology therapies prescribed. The stage 3 women in the naturopathic oncology group had more advanced disease at diagnosis. They were more likely to have 5 or more metastatic lymph nodes at baseline (18.5%) compared to their usual care matched control group (13%). Women in the naturopathic oncology group also had higher grade tumors at diagnosis. Conclusions: Results show that recurrence of breast cancer was associated with more advanced malignant lymph node involvement; and that naturopathic oncology services provided in 2009-2015 did not improve disease-free survival in these high-risk breast cancer patients.
The PKCγ neurons in anterior cingulate cortex contribute to the development of neuropathic allodynia and pain-related emotion
Authors: Zhang Xiao , Liu Peng , He Xiaolan , Jiang Zhenhua , Wang Qun , Gu Nan , Lu Yan 
Published: December 2021

Background While the PKCγ neurons in spinal dorsal horn play an indispensable part in neuropathic allodynia, the exact effect of PKCγ neurons of brain regions in neuropathic pain remains elusive. Mounting research studies have depicted that the anterior cingulate cortex (ACC) is closely linked with pain perception and behavior, the present study was designed to investigate the contribution of PKCγ neurons in ACC to neuropathic allodynia and pain-related emotion in newly developed Prkcg-P2A-Tdtomato mice. Methods The c-fos expression in response to innocuous stimulation was used to monitor the activity of PKCγ in CCI (chronic constriction injury of the sciatic nerve) induced neuropathic pain condition. Activating or silencing ACC PKCγ neurons by chemogenetics was applied to observe the changes of pain behavior. The excitability of ACC PKCγ neurons in normal and CCI mice was compared by patch-clamp whole-cell recordings. Results The PKCγ-Tdtomato neurons were mainly distributed in layer III-Vof ACC. The Tdtomato was mainly expressed in ACC pyramidal neurons demonstrated by intracellular staining. The c-fos expression in ACC PKCγ neurons in response to innocuous stimulation was obviously elevated in CCI mice. The patch clamp recordings showed that ACC PKCγ-Tdtomato neurons were largely activated in CCI mice. Chemogenetic activation of ACC PKCγ neurons in Prkcg-icre mice induced mechanical allodynia and pain-related aversive behavior, conversely, silencing them in CCI condition significantly reversed the mechanical allodynia and pain-related place aversive behavior. Conclusion We conclude that the PKCγ neurons in ACC are closely linked with neuropathic allodynia and pain-related emotional behaviors.
Long-term efficacy and safety of three times weekly dosing regimen of glatiramer acetate in relapsing multiple sclerosis patients: Seven-year results of the Glatiramer Acetate Low-frequency Administration (GALA) open-label extension study
Authors: Rieckmann Peter , Zivadinov Robert , Boyko Alexey , Selmaj Krzysztof , Alexander Jessica K. , Kadosh Shaul , Rubinchick Svetlana , Bernstein-Hanlon Emily , Stark Yafit , Ashtamker Natalia , Davis Mat D. , Khan Omar 
Published: December 2021

Objective Describe the long-term outcomes of early-start (ES) and delayed-start (DS) glatiramer acetate 40 mg/mL treatment three times weekly (GA40) for up to seven years in the Glatiramer Acetate Low-frequency Administration (GALA) study in patients with relapsing multiple sclerosis (RMS). Methods Patients were evaluated every three to six months. The primary efficacy endpoint was annualized relapse rate (ARR); additional endpoints were exploratory or post hoc. For efficacy, data from the entire exposure period were used for the ES and DS cohorts. For safety, exposure only under GA40 was considered. Results Of the patients who continued into the open-label extension (OLE), 580/834 (70%) ES and 261/419 (62%) DS completed the OLE. For the entire placebo-controlled and OLE study period, ARR was 0.26 for ES and 0.31 for DS patients (risk ratio = 0.83; 95% confidence interval [CI]: 0.70–0.99). ES prolonged median time to first relapse versus DS (4.9 versus 4.3 years; hazard ratio = 0.82; 95% CI: 0.6–0.96). OLE-only results showed DS patients experienced similar efficacy for relapse and disability outcomes as ES patients. Adverse events were consistent with the well-established GA safety profile. Conclusions GA40 treatment conferred clinical benefit up to seven years, resulting in sustained efficacy and was generally well tolerated in RMS patients.
Paramarkeyite, a new calcium–uranyl–carbonate mineral from the Markey mine, San Juan County, Utah, USA
Authors: Kampf Anthony R. , Olds Travis A. , Plášil Jakub , Burns Peter C. , Škoda Radek , Marty Joe 
Published: December 2021

AbstractThe new mineral paramarkeyite (IMA2021-024), Ca2(UO2)(CO3)3⋅5H2O, was found in the Markey mine, San Juan County, Utah, USA, where it occurs as a secondary phase on gypsum-coated asphaltum in association with andersonite, calcite, gypsum and natromarkeyite. Paramarkeyite crystals are transparent, pale green-yellow, striated tablets, up to 0.11 mm across. The mineral has white streak and vitreous lustre. It exhibits moderate bluish-white fluorescence (405 nm laser). It is very brittle with irregular, curved fracture and a Mohs hardness of 2½. It has an excellent {100} cleavage and probably two good cleavages on {010} and {001}. The measured density is 2.91(2) g cm–3. Optically, the mineral is biaxial (–) with α = 1.550(2), β = 1.556(2), γ = 1.558(2) (white light); 2V = 60(2)°; strong r > v dispersion; orientation: Y = b; nonpleochroic. The Raman spectrum exhibits bands consistent with UO22+, CO32– and O–H. Electron microprobe analysis provided the empirical formula (Ca1.83Na0.20Sr0.03)Σ2.05(UO2)(CO3)3⋅5H2O (+0.07 H). Paramarkeyite is monoclinic, P21/n, a = 17.9507(7), b = 18.1030(8), c = 18.3688(13) Å, β = 108.029(8)°, V = 5676.1(6) Å3 and Z = 16. The structure of paramarkeyite (R1 = 0.0647 for 6657 I > 2σI) contains uranyl tricarbonate clusters that are linked by Ca–O polyhedra to form heteropolyhedral layers. The structure of paramarkeyite is very similar to those of markeyite, natromarkeyite and pseudomarkeyite.