bluuebunny/crossref_metadata_2025_split huggingface dataset:
The iTHRIV Commons: a cross-institution information and health research data sharing architecture and web application
Authors: Loomba Johanna Jean , Wasson Glenn S , Chamakuri Ravi Kiran Reddy , Dash Pabitra Kumar , Patterson Stephen G , Potter Mary M A , Krisch Jason Edward , Tenzer Martha M , Johnston Karen C , Brown Don E 
Published: November 2021

Abstract

Objective
The integrated Translational Health Research Institute of Virginia (iTHRIV) aims to develop an information architecture to support data workflows throughout the research lifecycle for cross-state teams of translational researchers.

Materials and Methods
The iTHRIV Commons is a cross-state harmonized infrastructure supporting resource discovery, targeted consultations, and research data workflows. As the front end to the iTHRIV Commons, the iTHRIV Research Concierge Portal supports federated login, personalized views, and secure interactions with objects in the ITHRIV Commons federation. The canonical use-case for the iTHRIV Commons involves an authenticated user connected to their respective high-security institutional network, accessing the iTHRIV Research Concierge Portal web application on their browser, and interfacing with multi-component iTHRIV Commons Landing Services installed behind the firewall at each participating institution.

Results
The iTHRIV Commons provides a technical framework, including both hardware and software resources located in the cloud and across partner institutions, that establishes standard representation of research objects, and applies local data governance rules to enable access to resources from a variety of stakeholders, both contributing and consuming.

Discussion
The launch of the Commons API service at partner sites and the addition of a public view of nonrestricted objects will remove barriers to data access for cross-state research teams while supporting compliance and the secure use of data.

Conclusions
The secure architecture, distributed APIs, and harmonized metadata of the iTHRIV Commons provide a methodology for compliant information and data sharing that can advance research productivity at Hub sites across the CTSA network.
Drugstore Beetle Damage Pattern of Glue Paste-Lined Oil Paintings
Authors: Lee Wen-Yuan , Liu Kai-Yuan , Wu Wan-Yu , Tsai Cheng-Lung , Wu Wei-An , Li Hou-Feng 
Published: November 2021

Abstract
A glue paste lining is a traditional conservation treatment used to reinforce the aged canvas of oil paintings. Several insect infestation cases concerning glue paste-lined oil paintings have been reported around the world, particularly in European countries. In 2008, Chimei Museum, a private museum located in Tainan, Taiwan, was affected by a severe beetle infestation of oil paintings. To confirm the infesting insects and to quantify the damage pattern for further development of control and monitoring methods, three severely damaged paintings were examined along with the restoration procedure. A total of four insect species were collected. The drugstore beetle, Stegobium paniceum (L.) (Coleopter: Ptinidae), was the primary pest found in all three paintings investigated and was identified based on morphological and genetic data. Thrips and booklice were considered secondary pests, and a Pteromalid wasp was speculated to have a parasitic relationship with the drugstore beetle. Drugstore beetle larvae mainly bored into the glue paste layer and original canvas and required only 5.94 ± 1.38 mm3 of feed to grow from egg to pupa. Their bores were not evenly distributed, and most of them were found in the shaded area covered by the stretcher and outer frame. The body length of drugstore beetles varied, ranging from 1.67 to 2.75 mm, which may explain the various sizes of exit holes on gummed tape surrounding the frame. Detailed and quantified information on drugstore beetle’s pattern of damage provided in this study will be beneficial for further developing conservation practices and inspection methods.
Criminalization, Securitization and other Forms of Illegalizing Indigenous Contestations in Chile: Responses from Constitutional Law and Inter-American Jurisprudence on Mapuche People’s Rights
Authors: Eichler Jessika , Barnier-Khawam Pablo 
Published: November 2021

AbstractThis article critically examines the contemporary ‘securitization paradigm’ adopted throughout the Chilean jurisdiction. Emphasis is placed on its explicit misuse and its arbitrary effects on the Mapuche people in light of Chile’s anti-terrorism legislation. The law thereby assumes a twofold function. ‘Judicialization strategies’ are employed by different organs of the State, resulting in the criminalization and ultimately the silencing of indigenous protest and forms of representation in the public space. These potentially transform relations between the State and its subjects, demanding a repositioning of indigenous agendas and representation under the constitutional umbrella. Conversely, judicialization also assumes a mediating role through the virtuous effects of international law and Inter-American human rights jurisprudence. The newly commencing constitutional era may further spur such developments, potentially exerting essential decolonizing effects on State institutions and society at large.
Use of a Fluorophore to Tag Arthropods for Mark-Release-Recapture Type Research
Authors: Hagler James R , Hull Allya M , Casey Miles T , Machtley Scott A 
Published: November 2021

Abstract
We examined the feasibility of externally marking insects with the liquid fluorescent forensic theft deterrent, SmartWater (SmartWater CSI, LLC.). We sprayed captive Lygus hesperus (Knight) (Hemiptera: Miridae), Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae), and Hippodamia convergens Guérin-Méneville (Coleoptera: Coccinellidae) with SmartWater fluorophore, and then qualitatively examined them for fluorescence by visual inspection under ultraviolet (UV) light and quantitatively measured them with a multiwavelength microplate fluorometer. The results indicate that this product has enormous potential as a taggant for L. hesperus and B. tabaci. However, the marking efficiency for H. convergens was only adequate. The advantages and limitations of using SmartWater as a biological marker for arthropod mark-release-recapture research are discussed.
Bed site selection by female North American black bears (Ursus americanus)
Authors: Mansfield Susan A , Rogers Lynn L , Robison Sean , Powell Roger A 
Published: November 2021

Abstract
Sleep is important for memory consolidation and maintaining metabolic homeostasis, but sleep can expose animals to inclement weather and predators. Consequently, selection of sleeping sites is important. We tested three sets of hypotheses related to selection of bed sites by female American black bears (Ursus americanus) at two study sites. During 2009–2013, we outfitted 14 female black bears west of Ely, Minnesota, with Global Positioning System collars that reported bear locations every 10 min. We visited 101 bed sites, each identified from clusters of estimated locations where a bear was on site for ≥4 h on two or more occasions, and recorded bed characteristics, forest composition, canopy closure, and ground cover. We matched each bed site with a control site where we collected the same data. During 1987–1991, we outfitted three female black bears south of Ely with very high-frequency transmitter collars and walked with the bears to collect detailed behavioral data. We used the written data records to identify 62 bed sites where bears slept ≥2 h and where bed characteristics were documented. We matched each bed site with a control site approximately 6 h different when the bear was active. Of the bed sites, 132 were used during night and 31 during day. The two study areas differed in the amount of lowland habitats. At both sites, female bears chose bed sites disproportionately in lowland sites with high canopy cover and next to a tree, especially a white pine. Female bears with cubs selected upland bed sites more often than did females without cubs and also more often selected sites adjacent to a tree with coarse bark, which cubs could climb easily. Distances to roads and houses did not affect selection of bed sites by females either with or without cubs.
Mesenteric desmoid tumor after robot-assisted laparoscopic cystectomy with bladder replacement: a case report
Authors: Fukuhara Sotaro , Yoshimitsu Masanori , Yano Takuya , Chogahara Ichiya , Yamasaki Rie , Ebara Shin , Okajima Masazumi 
Published: November 2021

Abstract
Desmoid tumors are a very rare disease associated with familial adenomatous polyposis, surgical trauma and hormonal factors. Surgical trauma is a critical trigger for sporadic desmoid tumors. Tumor development has been reported, and laparoscopic surgery has become more widely performed than the conventional open surgery. However, a few cases of desmoid tumors have developed after robot-assisted surgery. When desmoid tumors develop after cancer surgery, they are often difficult to distinguish from cancer recurrence. This differentiation is important for patients with bladder cancer because it helps determine the treatment plan. However, very few cases of mesenteric desmoid tumors after cystectomy for bladder cancer have been reported. Herein, we present a case of desmoid tumor that developed following robot-assisted laparoscopic cystectomy for bladder cancer. The tumor was resected via minilaparotomy with laparoscopic assistance for diagnostic treatment.
Quality of Care Indicators for Hospital Physical Therapy Units: A Systematic Review
Authors: Angel-Garcia Daniel , Martinez-Nicolas Ismael , Salmeri Bianca , Monot Alizée 
Published: November 2021

AbstractObjectiveThe purpose of this review was to identify quality indicators described in the literature that may be used as quality measures in hospital physical therapy units.MethodsThe following sources were searched for quality indicators or articles: Web of Science, MEDLINE, IBECS, Latin American and Caribbean Health Sciences Literature, Cumulative Index of Nursing and Allied Health, Academic Search Complete, SportDiscus, SciELO, PsychINFO, Consejo Superior de Investigaciones Cientificas, and Scopus databases; the Agency for Healthcare Research and Quality, National Health System Indicator Portal, Joint Commission on Accreditation of Healthcare Organizations, and Organisation for Economic Co-operation and Development websites; and the National Quality Forum’s measures inventory tool. Search terms included “quality indicator,” “quality measure,” “physiotherapy,” and “physical therapy.” Inclusion criteria were articles written in English, Spanish, French, or Portuguese aimed at measuring the quality of care in hospital physical therapy units. Evidence-based indicators with an explicit formula were extracted by 2 independent reviewers and then classified using the structure-process-outcome model, quality domain, and categories defined by a consensus method.ResultsOf the 176 articles identified, only 19 met the criteria. From these articles and from the indicator repository searches, 178 clinical care indicators were included in the qualitative synthesis and presented in this paper. Process and outcome measures were prevalent, and 5 out of the 6 quality domains were represented. No efficiency measures were identified. Moreover, structure indicators, equity and accessibility indicators, and indicators in the cardiovascular and circulatory, mental health, pediatrics, and intensive care categories were underrepresented.ConclusionsA broad selection of quality indicators was identified from international resources, which can be used to measure the quality of physical therapy care in hospital units.ImpactThis review identified 178 quality of care indicators that can be used in clinical practice monitoring and quality improvement of hospital physical therapy units. The results highlight a lack of accessibility, equity, and efficiency measures for physical therapy units.
Documenting development of interdisciplinary collaboration among researchers by visualizing connections
Authors: Higgins Linden E , Smith Julia M 
Published: November 2021

AbstractIn 2015, a multidisciplinary group of academic researchers and extension personnel was awarded a US Department of Agriculture Coordinated Agricultural Project grant. The team’s goal was to understand human decision-making in the context of potential livestock disease outbreaks, investigating the impediments to increased adoption of biosecurity practices by producers from multiple perspectives. Counting publications and presentations was not deemed adequate evidence of growth of interdisciplinary collaboration. Instead, we took a developmental evaluation approach, collecting data to illuminate patterns of interconnectedness across disciplinary boundaries. These data, mapped annually on a baseline framework, reveal the team moving from disciplinary groups with disparate epistemologies and interests to a cohesive interdisciplinary team involved in many unexpected and emergent projects.
Understanding resistant hypertension
Authors: Bachinsky Alexandra , Jones Erin Leah , Thompson Tiffany , DePalma Sondra , Nicholas Joyce , Schmidt Eric 
Published: November 2021

ABSTRACT
Resistant hypertension affects about 17% of the US population. However, it is difficult to diagnose because of multiple factors that influence adequate treatment of BP, including patient lifestyle and comorbidities, improper therapeutic regimens, and secondary mechanisms. Possible causes of resistant hypertension include nonmodulator hypertension, which affects patients who have an inappropriate response to elevated sodium through the renin-angiotensin-aldosterone system. Early identification and frequent follow-up can help patients achieve BP goals more rapidly and may reduce morbidity and mortality associated with complications of hypertension, including cerebrovascular accident, cardiovascular disease, and kidney disease.
Adhesive capsulitis
Authors: Ricci Monica 
Published: November 2021

ABSTRACT
Adhesive capsulitis, a common primary care and orthopedic diagnosis often referred to as frozen shoulder, is a painful inflammatory process that leads to a mechanical block in active and passive range of shoulder motion. Risk factors include diabetes and thyroid dysfunction. Diagnosis is made based on physical examination, but can be augmented by diagnostic imaging. Nonsurgical management is the mainstay of treatment because the disease is self-limiting. However, some patients may need surgical intervention.
Effect of a PA-led arthritis center on hip and knee osteoarthritis care
Authors: Kelly McKayla , Aja Jacob , Turcotte Justin , MacDonald James 
Published: November 2021

ABSTRACT

Objective:
To evaluate the effect of an arthritis center on patient care and operational throughput.

Methods:
A single-institution, retrospective review was conducted of patients with hip or knee osteoarthritis from January 2016 to October 2019. Our physician assistant (PA) led arthritis center opened in November 2017, and manages nonoperative treatment of osteoarthritis by formulating individualized treatment plans. Descriptive and inferential statistics comparing operational measures, treatment patterns, and patient satisfaction pre- and postcenter opening were performed.

Results:
Overall patient volume, new patient volume, and the proportion of new patients seen increased after the arthritis center opened. Encounters per patient and clinicians seen per patient decreased, while the rate of injections and surgery increased. Patient satisfaction improved after opening of the arthritis center.

Conclusions:
The establishment of a dedicated PA-led arthritis center is associated with improved access to care, operational efficiency, and patient satisfaction in patients with hip and knee osteoarthritis.
PA- and NP-led Ommaya clinics to manage leptomeningeal carcinomatosis
Authors: Leese Erika N. , Weeder Jamie L. , Manikowski Jesse J. , DeLaRue Angela M. , Conger Andrew R. , Mahadevan Anand , Vogel Victor G. , Mongelluzzo Gino J. , Gatson Na Tosha N. 
Published: November 2021

ABSTRACT

Objectives:
Physician assistants (PAs) and NPs are essential to quality care delivery. The need to demonstrate value and optimize PA and NP roles in neurology subspecialty clinics is unmet. We outline the development of a PA- and NP-led neuro-oncology procedural clinic and provide metrics to support the institutional and clinician value added.

Methods:
We designed a PA- and NP-led Geisinger Ommaya Clinic (GOC) to manage leptomeningeal carcinomatosis (LMC) with defined clinician roles and the GOC treatment protocol. A retrospective review of 135 patients (2012-2019) compared survival outcomes for patients treated on the protocol compared with those treated off the protocol.

Results:
Centralized care in the GOCs minimized shared physician encounters and improved PA and NP autonomy and utility. LMC therapy as part of the GOC protocol improved care continuity and survival outcomes.

Conclusions:
PA- and NP-led procedural clinics optimize use of these clinicians and open physician availability for nonprocedural duties. This research highlights the institutional patient and financial benefit while demonstrating the operational and leadership growth potential for PAs and NPs.
Critically appraising the 2018 United Network for Organ Sharing donor allocation policy: adding life boats or rearranging the deck chairs?
Authors: Truby Lauren K. , Farr Maryjane , Topkara Veli K. 
Published: November 2021

Purpose of review
Due to the growing mismatch between donor supply and demand as well as unacceptably high transplant waitlist mortality, the heart organ allocation system was revised in October 2018. This review gives an overview of the changes in the new heart organ allocation system and its impact on heart transplant practice and outcomes in the United States.

Recent findings
The 2018 heart allocation system offers a 6-tiered policy and therefore prioritizes the sickest patients on the transplant waitlist. Patients supported with temporary mechanical circulatory support devices are prioritized as Status 1 or Status 2, resulting in increased utilization of this strategy. Patients supported with durable left ventricular assist devices have been prioritized as Status 3 or 4, which has resulted in decreased utilization of this strategy. Broader geographic sharing in the new heart allocation system has resulted in prolonged donor ischemic times. Overall, the new heart allocation system has resulted in significantly lower candidate waitlist mortality, shorter waitlist times, and higher incidence of transplantation.

Summary
The new United Network for Organ Sharing allocation policy confers significant advantages over the prior algorithm, allowing for decreased waitlist times and improved waitlist mortality without major impact on posttransplant survival.
Is single posterior approach sufficient for effective hemivertebra resection and correction of nonflexible curves? A prospective study
Authors: Ashour Mahmoud Ahmed , Zaher Naser Hussin , Elsayed Mohamed Nabil , EL Zahlawy Hany , Hussien Mohamed Ali , Elkhateeb Tameem Mohamed 
Published: November 2021

Background:
The purpose of this study was to evaluate the results of posterior-only resection of hemivertebrae in correction of congenital spinal deformities.

Methods:
Thirty consecutive patients with scoliosis, kyphosis, or kyphoscoliosis that was caused by congenital hemivertebra were included. Preoperative calculations of the curve degree and stiffness were obtained, and postoperative magnitude of corrections were calculated. The mean percentage of correction was measured. Intraoperative and postoperative complications were stated. The mean follow-up period was 48 mo.

Results:
The mean age of the patients was 11 yr. Scoliosis was found in 20 patients, pure kyphosis was found in six patients, and kyphoscoliosis was found in four patients. The deformity was in the thoracic region in nine patients, thoracolumbar region in 16, and lumbar region in five. Each patient had a single hemivertebra and primary posterior hemivertebra resection. The mean preoperative coronal Cobb angle in both the scoliosis and kyphoscoliosis patients was 49 degrees. The angle improved to a mean of 10.8 degrees at final follow-up with mean correction of 38.2 degrees. The mean preoperative local kyphosis angle in the kyphosis and kyphoscoliosis patients was 73.1 degrees. This improved to a mean of 21.1 degrees postoperatively with mean correction of 52 degrees. The mean preoperative regional angulation in those patients was 67.1 degrees, which improved to a mean of 24.6 degrees postoperatively with a mean correction of 42.6 degrees. Improvements in all these values were statistically highly significant (P < 0.001). Complications were recorded in six patients and included dural tear, pleural tear, and postoperative wound infection, which were managed.

Conclusions:
The posterior-only approach in hemivertebra resection can achieve good deformity correction and solid fusion with low risk of neurological complications.

Level of Evidence:
Level IV.
Surgical correction of Scheuermann’s kyphosis by posterior-only approach: a prospective study
Authors: Zayan Ibrahim Mohammed , Elkhateeb Tameem Mohamed , EL Zahlawy Hany 
Published: November 2021

Background:
The authors aimed to evaluate the clinical and radiographic results of the posterior-only approach in the treatment of Scheuermann’s kyphosis using pedicle screws with Ponte osteotomies.

Methods:
Twenty-one consecutive patients with Scheuermann’s kyphosis within the operative range were included in this prospective study. Patients were operated by a posterior-only approach using pedicle screws. Multiple Ponte osteotomies were performed at and around the apex. Mean operative time, blood loss, and any complications related to the procedure were reported. Patients were assessed radiographically by measuring thoracic kyphosis angle, lumbar lordosis angle, sagittal balance, and the Voutsinas index of kyphosis. Patients were assessed clinically using the Scoliosis Research Society questionnaire (SRS-22).

Results:
There were 18 male patients and 3 female patients with a mean age of 21 yr. The mean blood loss was 847.6 cc. The mean operative time was 196.9 min. The mean follow-up period was 36 mo. The mean preoperative thoracic kyphosis was 78.1±5.8 degrees, which improved to 41.9±3.7 degrees postoperatively. At the final follow-up, the mean thoracic kyphosis was 42.3±3.8 degrees. The mean lumbar lordosis was 71.1±3.4 degrees preoperatively, 51.6±1.7 degrees postoperatively, and 53.4±3.7 degrees at the final follow-up. The mean Voutsinas index of kyphosis was 19.6±7.6 preoperatively, which became 13.4±4.8 early postoperatively and 13.5±3.6 at the final follow-up. The SRS 22 questionnaire improved significantly from a mean of 2.7±1.3 preoperatively to 4.3±2.2 at the final follow-up.

Conclusions:
The posterior-only approach is a successful technique in treatment of Scheuermann’s kyphosis.

Level of Evidence:
Level IV.