bluuebunny/crossref_metadata_2025_split huggingface dataset:
Medicinal benefits and scientific justification of Commiphora mukul (Muqil): A review
Authors: Bhat Shabir Ahmad , Rather Shameem Ahmad 
Published: February 2021

Commiphora mukul (Muqil or Guggul), oleo-gum, has been in use for thousands of years as a medicine in Unani and Ayurvedic medicinal systems. It was primarily used for swellings, inflammation, piles, arthritis and urinary disorders. Among its various types Muqil-I-Arzaq, a gum, having reddish hue is considered to be the best form of Muqil for medicinal purposes. It has been revealed to inhibit the nuclear factor-kb, a regulator of inflammatory response, and act as a potent antagonist to the receptors of androgens, mineralocorticoides, and glucocorticoides. Muqil is a versatile herb with diverse medicinal benefits which demand scientific validation. A coherent review of properties, medicinal benefits, traditional uses and scientific studies of Muqil, along with the overall processes involved from collection to consumption is judiciously described in this paper. The aim of this review is to provide a base for multiple research works, validating Commiphora mukul in different chronic ailments.
keywords: Commiphora mukul, Inflammation, Muqil, Nuclear factor-KB, Unani
History of Ayurvedic System of Medicines: From Prehistoric to Present
Authors: Tiwari S. B. , Singh S. D. , Verma Amit Kumar , Awasthi Divyank , Rastogi Arun Kumar 
Published: February 2021

Ayurvedic system of medicine is considered the most ancient system of the world. In the prehistoric times medicinal plants were used by the various tribes. Evidence suggests that the people of Indus valley civilization followed this system of medicines. The Vedic and post Vedic period saw the rapid development of Ayurveda supported by the efforts of Charaka, Susrutra and Vagbhata etc. Buddhist monks played important role in the propagation of Ayurveda. However, the invasion of Muslims after 10th century destroyed Ayurveda and Unani system of medicines flourished in the country. Pre independence period again saw the emergence of Ayurveda. After Independence it attains new height with its incorporation into the Drug and Cosmetic Act. The preparation of Ayurvedic Pharmacopoeia helps in the standardization of Ayurvedic drugs to compete at global level with allopathic system of medicines.
Keywords: ayurvedic system, Vedic and post Vedic period, Charaka, Susrutra and Vagbhata, Ayurvedic drugs
QSAR and docking studies of 3, 5-dimethylpyrazole as potent inhibitors of Phosphodiesterase-4
Authors: Mahgoub Mohamed Hiba Hashim , Mohammed Hussien Amna Bint Wahab Elrashid , Mohammed Saeed Ahmed Elsadig 
Published: February 2021

A quantitative structure-activity relationship (QSAR) study was performed to develop a model on a series of 3, 5-dimethylpyrazole containing furan moiety derivatives which exhibited considerable inhibitory activity against PDE4B. The obtained model has correlation coefficient (r) of 0.934, squared correlation coefficient (r2) of 0.872, and leave-one-out (LOO) cross-validation coefficient (Q2) value of 0.733. The predictive power of the developed model was confirmed by the external validation which has (r2) value of 0.812. These parameters confirm the stability and robustness of the model to predict the activity of a new designed set of 3,5-dimethyl-pyrazole derivatives (I-XV), results indicated that the compound III, V, XIII, and XV showed the strongest inhibition activity (IC50 = 0.2813, 0.5814, 0.6929, 0.6125μM, respectively) against PDE4B compared to the reference rolipram with (IC50=1.9μM). Molecular docking was performed on a new designed compound with PDE4B protein (3o0j). Docking results showed that compounds (X and IX) have high docking affinity of -36.2037 and -33.2888 kcal/mol respectively.
Keywords: QSAR, molecular docking, pyrazole derivatives, PDE4 inhibitors, anti-inflammatory.
The Antimicrobial Activity of Quercus Infectoria Extracts Against Bacteria Isolated from Wounds Infection
Authors: Hanon Noor Ameer , Abd Fouad Najm 
Published: February 2021

Bacteria that cause wound infections were isolated and diagnosed from patients, who were hospitalized at the Martyr Al-Sadr Hospital from October 2019 to April 2020. Antibacterial effect of Quercus infectoria extract (aqueous and alcoholic) on the isolated bacteria has been studied. The results showed that the alcoholic extract has a higher antibacterial effect than the aqueous extract against Gram-positive bacteria like Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus saprophyticus except Micrococcus roseus, which the effect of aqueous extract was higher than alcoholic extract, whereas aqueous and alcoholic extracts showed the same effect against Streptococcus sp.. The alcoholic extract has higher antibacterial effect than the aqueous extract against Gram-negative bacteria (Escherichia coli, Pseudomonas sp., Enterococcus faecalis, Shigella dysnteriae, Enterobacter sakazkii, citrobcter freundii and Alcaligenes faecalis) except proteus sp., which the aqueous extract was higher than alcoholic extract.
KORELASI KETERAMPILAN MEMBACA PEMAHAMAN DAN KETERAMPILAN MENULIS TEKS LAPORAN HASIL OBSERVASI SISWA KELAS VII SMP NEGERI 4 PARIAMAN
Authors: Putri Diana , R. Syahrul 
Published: February 2021

ABSTRACT This research focus on the describing skill correlation of reading understanding and skill text writing report observation results of the seventh grade students of SMP Negeri 4 Pariaman. This type of research is quantitative research with correlational methods. The sample of this research is students of SMP Negeri 4 Pariaman amounted 42 students. The data of this research are the score of the reading comprehension skill test results and the score of the test results in the writing skills of the report text of the seventh grade students of SMP Negeri 4 Pariaman. Based on the research, it can be concluded that there is a significant relationship between reading skills understanding of the report writing skills in the text of the observation results of seventh grade students of SMP Negeri 4 Pariaman. Based on analysis data and discussion, there are several conclusion obtained. First, the skill of Report Writing Text Results of Observation of seventh grade Students of SMP Negeri 4 Pariaman is in good qualification (80.95). Second, the skill of reading Comprehension of seventh grade Students of SMP Negeri 4 Pariaman is in good qualification (80.36). Kata kunci: Korelasi, Membaca Pemahaman, Menulis, Teks Laporan Hasil Observasi
PENGARUH TEKNIK PEMBELAJARAN THINK TALK WRITE (TTW) BERBANTUAN MEDIA GAMBAR BERSERI TERHADAP KETERAMPILAN MENULIS TEKS FABEL
Authors: Wahyuni Nendi Dwi , Thahar Harris Effendi 
Published: February 2021

ABSTRACT The purpose of this writing is to research the influence of TTW’s learning by using picture in series as the media towards class VII of SMP Negeri 2 2X11 Enam Lingkung’s students’ skill on writing fable. The data of this research are the students’ scores of writing fables. It is collected by doing the test of writing fable toward the sample before and after using TTW’s technique by using picture in series. The result of this technique is using T-test formula. The result of this research showing 1) the writing skill of fable before and after using TTW’s technique of picture in series are in “Lebih dari Cukup” (LdC) qualification; 2) the writing skill of fable before and after using TTW’s technique of picture in series are in the “Baik Sekali” (BS) qualification and 3) as the result of using T-test formula showing that the writing skill of fable before and after using TTW’s technique of picture in series giving very good influence towards the students’ skill of writing fable text in class VII of SMP Negeri 2 2X11 Enam Lingkung. Kata kunci: Pengaruh, TTW Berbantuan Media Gambar Berseri, Keterampilan Menulis Teks Fabel
PENGARUH MODEL PEMBELAJARAN KOOPERATIF TIPE THINK TALK WRITE (TTW) BERBANTUAN MEDIA AUDIOVISUAL TERHADAP KETERAMPILAN MENULIS TEKS PERSUASI SISWA KELAS VIII SMP NEGERI 8 PADANG
Authors: Mulyani Riska , R., Syahrul 
Published: February 2021

ABSTRACTThe purpose of this study was categorized into three. First, to describe the text writing skills of the experimental class persuasion students. Second, to describe the text writing skills of the control class students' persuasion. Third, to describe the influence of the cooperative learning which was Think Talk Write (TTW) model assisted by audiovisual media in writing skill related to the persuasive text of class VIII students of SMP Negeri 8 Padang. The type of study was quantitative with quasi-experimental research. The design of this study was static by two groups. The population in this study was VIII grade students of SMP Negeri 8 Padang who were enrolled in 2018/2019 academic year about 252 students. The sample in this study was 64 students that consist of two classes, namely class VIII A as the experimental class and class VIII D as the control class that was taken by using purposive random sampling technique. There were several results of this study. They were: First, persuasive text writing skill of the experimental class students was in the category Very Good (BS) with an average score of 85.94. Second, persuasive text writing skill of control class students was in the category Good (B) with an average score of 76.82. Third, the working hypothesis (H_1) was received at the level of α = 0.05 and degrees of freedom (dk) = (n1 + n2) -2 because of tcount>ttable, which is 4.23> 1.70. In other words, the use of model cooperative learning type Think Talk Write assisted by audiovisual media has a significant effect on the persuasive writing skills of class VIII students of SMP Negeri 8 Padang. Therefore, the cooperative learning type Think Talk Write (TTW) model could be used as an alternative in learning persuasive text writing skill at the junior secondary level. Kata kunci: Pengaruh, Think Talk Write , Media Audiovisual, Teks Persuasi
«Literatura y nación. Preliminares de historia literaria. (Una Antología)», de Marcelino Menéndez Pelayo
Authors: Moyano Arellano Claudio 
Published: February 2021

Reseña del libro Literatura y nación. Preliminares de historia literaria. (Una Antología) (estudio y edición de Joaquín Álvarez Barrientos, Pamplona, Urgoiti Editores, 2019), de Marcelino Menéndez Pelayo, .
Women Empowerment : Latkapuan Menanam Sebagai Upaya Mewujudkan Ketahanan Pangan di Tengah Pandemi Covid-19
Authors: Sampoerno Sampoerno , Septiana Wahyu , Tatiwakeng Diemas , Pakpahan Julios Carlos , Nugroho Christian Adi , Putra Yulius Farchan Dwi , Palupi Dewi Retno , Prasetyo Rian Adi , Dewi Malinda , Apriani Shela , Martins Mathelda Evania Oktiasni Eulalia 
Published: February 2021

Latkapuan menanam merupakan program kegiatan yang dilakukan oleh mahasiswa Fakultas Ilmu Sosial dan Ilmu Komunikasi Universitas Kristen Satya Wacana sebagai bentuk dari pengabdian mahasiswa kepada masyarakat. Program ini ditujukan untuk ibu-ibu bhayangkari yang tinggal di asrama Pusdik Binmas Lemdiklat Polri, Banyubiru. Latkapuan menanam juga merupakan bentuk pemberdayaan perempuan di tengah kondisi pandemic covid-19. Latkapuan menanam memiliki tujuan untuk meningkat kemampuan ibu-ibu bhayangkari dalam kegiatan menanam dengan cara memanfaatkan lahan pekarangan dan limbah rumah tangga. Metode pelaksanaan program latkapuan menanam diawali dengan sosialisasi program, pelaksanaan program yang meliputi pelatihan, monitoring, dan pemberian awards kepada peserta latkapuan menanam.
MyDispense: Lessons from Global Collaboration in Developing a Pharmacy Educational Simulation Tool
Authors: Costelloe Marian T 
Published: February 2021

The current focus on global workforce development in pharmacy provides a perfect stage for continued and extended collaboration between educators, researchers, and practitioners. One such global educational project is the MyDispense Project, which is a collaborative journey that started with an educational need. MyDispense is an online pharmacy simulation tool that teaches dispensing skills to students. Development of the tool began as a need for Australian pharmacy students, but has been customized for other parts of the world as well. Since the project’s launch in 2010, the ongoing use and development of the tool is a compelling story of success for global collaboration in pharmacy education. Lessons can be learned from this collaborative endeavour.

Type: Commentary
COMPARISON BIOLARVICIDES POTENCIAL OF FRUIT SEEDS AND LEAF PAPAYA EXTRACTS (Carica papaya) ON Aedes aegypti
Authors: Corona Fidel , Joprang Freggy Spicano 
Published: February 2021

Introduction: Aedes aegypti is the major vector of dengue virus. Dengue virus can cause dengue hemorrhagic fever (DHF). DHF is dangerous because it can cause death. World Health Organization (WHO) noted Indonesia as state with the highest dengue cases in Southeast Asia. Effort to control A. aegypti vector that can be done is by using natural substances that have the effect of biolarvicides. This study aims to determine natural biolarvicides potencial of fruit seeds and leaf papaya (Carica papaya) extracts against A. aegypti larvae.
Methods: This study was an experimental study and conducted in 2016 using two groups of samples with the design before and after intervention. Samples were A. aegypti larval instar III and IV with the number of 10 larvaeper concentration and 10 larvae of control for each types of extracts. The concentration used was 0 mg / L (control), 50 mg / L, 100 mg / L, and 150 mg / L for both types of extracts, then observed at 6 hours, 12 hours, 18 hours, and 24 hours after exposure.
Results: This study using Kruskal Wallis test, p value = 0.352. (P> 0.05) means there is no significant difference in the effect of biolarvicides concentration between the two types of extracts that used to the number of dead larvae of A. aegypti.
Conclusion: Fruit seeds and leaf papaya extracts (C. Papaya L.) with concentrations of 50 mg / L, 100 mg/ L, and 150 mg / L are not effective to kill the larvae of A. aegypti. Other studies show concentrations above 21.9 ppm of leaf extract and 442 ppm of fruit seed extract can effectively kill larvae, therefore future studies are needed to determine effective extract concentrations to kill the larvae of A. aegypti.
A DESCRIPTIVE STUDY OF COMMUNITY HEALTH POST VISITORS IN TWO HAMLETS IN KELURAHAN PEJAGALAN
Authors: Astiarani Yunisa , Kristian Kevin 
Published: February 2021

Introduction: A community-based health post called ‘pos pembinaan terpadu’ (Posbindu) is a vital approach to NCDs prevention and control strategy in the community. However, the posts appear to receive low appreciation in urban areas, with less than 10% of the population at risk visiting the post. This study presented a descriptive evaluation in Posbindu visitors after half-year implementation in two hamlets in Pejagalan.
Methods: A survey-based study was conducted in two Posbindu, each in a hamlet. A self-questionnaire regarding sociodemography, NCDs status, risk factors, visiting frequency and health-seeking behaviour were asked to all visitors and collected during Posbindu schedule.
Results: Posbindu visitors in hamlet A and B (131 and 160) share common demographic characteristics, with women participation higher in both (Hamlet A= 90.1% and Hamlet B=80.6%) mostly in their 30-44 age group for hamlet A (38.9%) and 45-59 age group for hamlet B (50%). Homemakers and unemployed were more than 70% of the proportion with low education preceding (40%) in both hamlets. NCDs status slightly higher in hamlet A (54.1%) than in B (53.7%), with hypertension, occupied the most. More than 90% of visitors lack in physical activity. Health seeking behaviour is better in diabetes sufferer than hypertension.
Conclusion: Posbindu visitors are usually housewives or unemployed group due to limitation of schedule. School and workplace-based NCDs prevention program have to be in consideration. Open space facilities on increasing the community's physical activity and intensive health literacy are necessary to maintain their healthy life years.
THE RELATION BETWEEN WATER CONTENT IN CONTACT LENS AND DRY EYE SYNDROME (DES) IN STUDENTS OF ATMA JAYA CATHOLIC UNIVERSITY OF INDONESIA SCHOOL OF MEDICINE AND HEALTH SCIENCES
Authors: Benita Levina , Kuswidyati Cisca , Chriestya Febie 
Published: February 2021

Introduction: Dry Eye Syndrome (DES) is a multifactorial disease of the eye characterized by loss of homeostasis from the tear film and is accompanied by ocular symptoms. One of many factors that can cause DES is the use of contact lenses. This research was conducted to determine the relationship of water content in contact lenses with the occurrence of DES.
Methods: This research was conducted in 2019 with a cross-sectional study design with the Tear Break Up Time (TBUT) test, Schirmer test and questionnaire. The research respondents were students of Atma Jaya School of Medicine and Health Sciences (FKIK UAJ) whose eyes were examined as samples (n = 84). The water content of the respondent's contact lenses was obtained using a questionnaire. The inspection methods used to determine DES are TBUT test and Schirmer test. Data analysis using chi-square test with significance level of p <0.05.
Results: The prevalence of DES obtained in students with a water content <50% is 25.9%, while the DES in students with a water content >50% is 25.5% .
Conclusion: There is no significant relationship between water content in contact lenses with the occurrence of DES in FKIK UAJ students (p=0.963).
RELATIONSHIP BETWEEN SUCCESSFUL TREATMENT OF PULMONARY TUBERCULOSIS PATIENTS WITH THE AVAILABILITY OF TREATMENT SUPPORTER IN ATMA JAYA HOSPITAL
Authors: Dailami Fariz Abdul Mujib , Wiraharja Regina Satya , Chriestya Febie 
Published: February 2021

Introduction: One of the biggest health problems faced by community is pulmonary tuberculosis (TB).TB is an respiratory tract infectious disease caused by Mycobacterium Tuberculosis. World Health Organization (WHO) recommends TB treatment with Directly Observed Treatment Short-course (DOTS) strategy, one of which is through the help of treatment supporter (PMO or Pengawas Minum Obat) who supervises the patient during the treatment period.
Methods: This was an analytic descriptive study with cross sectional approach.. Respondents were taken by consecutive sampling, based on medical records at Atma Jaya Hospital. We applied inclusion criteria such as newly diagnosed TB patient with positive sputum smear microscopy results, adult TB patient who has finished 6 month of treatment and patients who have done sputum smear microscopy test after finishing their TB treatment. The exclusion criteria were TB-HIV patients and Milliary TB patients. After fulfilment of those criteria, a total of 81 respondents were selected. Data was analysed by Chi Square test (Fisher Exact test).
Results: Most of patients were 15-50 years old (70,4%) with mean age at 38.49±17.83 years old),male (53.1%), had family as treatment supporter (91.4%) and had successful TB treatment (74.1%). TB patients with treatment supporter had more successful treatment (66.7%) than TB patients with no treatment supporter (7.4%), however there was no significant among the avalibility of treatment supporter and the success of TB treatment (p=0.670).
Conclusion: Despite the insignificant result, this study gives good insight to implementation of TB DOTS strategy in Atma Jaya Hospital. The implementation of this strategy contributes to imbalance number of samples between patient with and without treatment supporter, leading to overestimate results on with TB treatment supporter group.
PENGARUH PROSES AKTIVASI KIMIA TERHADAP KARAKTERISTIK ADSORBEN DARI KULIT PISANG KEPOK (Musa acuminate L.)
Authors: Sa’diyah Khalimatus , Lusiani Cucuk Evi , Chrisnandari Rosita Dwi , Witasari Wianthi Septia , Aula Diah Lailatul , Triastutik Sinta 
Published: February 2021

Kulit pisang dianggap sebagai limbah yang tidak berguna dan menimbulkan pencemaran lingkungan. Namun sebenarnya, kulit pisang dapat digunakan sebagai bahan adsorben untuk mengikat ion logam berat karena mengandung selulosa dan pektin. Penelitian ini bertujuan untuk mengetahui karakteristik adsorben yang dihasilkan terhadap jenis aktivator yaitu aktivator asam dan basa. Pembuatan adsorben menggunakan bahan kulit pisang yang sudah dikeringkan dikarbonisasi pada suhu 400°C selama 1,5 jam. Setelah proses karbonasi, adsorben diaktivasi menggunakan aktivator basa (larutan NaOH) dan aktivator asam (larutan H2SO4) dengan konsentrasi 2 N selama 5 jam. Berdasarkan hasil penelitian, limbah kulit pisang kepok yang telah mengalami karbonasi memiliki kandungan yang terdiri dari 8,42% kadar air, 11,15% kadar abu, 24,65% kadar volatile matter, dan 55,78% kadar Fixed Carbon. Adsorben dengan aktivator basa memberikan nilai kadar air, abu, dan volatile matter yang lebih tinggi dibandingkan aktivator asam. Namun, nilai kadar fixed carbon dan daya serap adsorben terhadap iodium pada aktivator basa lebih rendah daripada aktivator asam. Pada aplikasi limbah nikel, aktivator basa memberikan nilai penurunan kadar nikel lebih tinggi daripada aktivator asam. Kata kunci : Adsorben, karakteristik, aktivator, kulit pisang kepok
La injusticia y el chinche
Authors: Velarde Héctor 
Published: February 2021

Uno está en todo; todo está en uno. Esta es la mejor manera de considerar la armonía universal. Así quedamos de acuerdo con casi todas las religiones respetables, con la razón desconfiada y con el equilibrio de las cosas si es que realmente existe.
El Gr an Todo es un hecho rotundo. Los pequeños todos son hechos naturalmente menores y a las partículas de los más pequeñitos no tenemos por qué quitarles su modesta evidencia aunque no logremos pescarla. Esto es muy lógico. Ahora bien, el Gran Todo es de índole divina, es Dios, puesto que presenta una serie de características sorprendentes: no principia ni acaba y es unidad al mismo tiempo, vive eternamente de sí mismo, están en todas partes, en fin, nos hace toda clase de demostracion es de su maravilloso ser sin que nosotros podamos comprender un palote de sus trucos. Negar estas prestidigitacion es de orden superiores negar la luz. De esta categor ía son todas las grandes verdades.
Las nuevas formas laborales en la economía del precariado. El caso de los repartidores a domicilio de las plataformas Rappi, Uber Eats y Glovo
Authors: Carrión Chulluncuy Joselyn , Ticona Fernández Dávila Rubén 
Published: February 2021

La economía neoliberal en su proceso de expansión y continua capacidad de reinvención se ha adaptado a los nuevos contextos de crisis económicas, y ha generado relaciones socioeconómicas bajo nuevas formas laborales y mecanismos de trabajo. Es así como desde la última década han surgido masivamente trabajos precarios en la denominada economía colaborativa que reproducen y extienden la continua informalización y precariedad del empleo en la sociedad peruana, ahora envuelta en el discurso del emprendedurismo. El objetivo del artículo es analizar las nuevas formas laborales emergentes en la economía del precariado, a partir del estudio de casos de los repartidores a domicilio de las plataformas Rappi, Uber Eats y Glovo. La metodología utilizada ha sido cualitativa, se realizó 12 entrevistas a profundidad, el trabajo de campo se aplicó entre el 2018-2019 en Lima Metropolitana.