bluuebunny/crossref_metadata_2025_split huggingface dataset:
Towards Data Driven Stamping Process Modelling by Optical Inline Monitoring of Cutting Surface Parameters
Authors: Lorenz Maximilian , Menzl Matthias , Donhauser Christian , Layh Michael , Pinzer Bernd R. 
Published: April 2021

Abstract
Stamping is a wide-spread production process, applied when massive amounts of the ever-same cheap parts are needed. For this reason, a highly efficient process is crucial. The cutting process is sensitive to a multitude of parameters. A process that is not correctly adjusted is subject to considerable wear and therefore not efficient. Unfortunately, the precise dependencies are often unknown. A prerequisite for optimal, reproducible and transparent process alignment is the knowledge of how exactly parameters influence the quality of a cutting part, which in turn requires a quantitative description of the quality of a part. A data driven approach allows to meet this challenge and quantify these influences. We developed an optical inline monitoring system, which consists of a image capturing, triangulation and image processing, that is capable of deriving quality metrics from 2D images and triangulation data of the cutting surface, directly inside the machine and without affecting the process. We identify features that can be automatically turned into quality metrics, like fraction of the burnish surface or the cut surface inclination. As an application, we show that the status of tool wear can be inferred by monitoring the burnish surface, with immediate consequences for predictive maintenance. Furthermore, we conclude that connecting machine and process parameters with quality metrics in real time for every single part enables data driven process modelling and ultimately the implementation of intelligent stamping machines.
Preoperative ALBI grade predicts the outcomes in non-B non-C HCC patients undergoing primary curative resection
Authors: Tsai Yu-Chieh , Sou Fai-Meng , Liu Yueh-Wei , Yong Chee-Chien , Huang Pao-Yuan , Cho Wei-Ru , Hu Tsung-Hui , Tsai Ming-Chao , Wu Yi-Ju , Chen Ding-Wei , Chuang Ching-Hui , Hsiao Chang-Chun 
Published: April 2021

Abstract
Background The albumin-bilirubin (ALBI) grade has been validated as a significant predictor for hepatocellular carcinoma (HCC). However, there is little information about the ALBI grade in patients with non-B non-C HCC (NBNC-HCC) receiving surgery. Aim This study aimed to evaluate ALBI grade as a prognostic factor in patients with NBNC-HCC after primary curative resection. Method This retrospective study enrolled 2137 HCC patients, who received HCC resection between January 2001 and April 2016 at Kaohsiung Chang Gung Memorial Hospital. With exclusion criteria of patients who had chronic hepatitis B or chronic hepatitis C, and prior HCC treatment before resection and received liver transplantation and BCLC stage B or C, finally we enrolled 168 NBNC-HCC patients who received primary curative resection. ALBI score used for grading as well as clinic opathologic features was analyzed, the formula of ALBI score was log10 [albumin (mg/dL) x 17.1] x 0.66 – albumin (g/dL) x 0.85. Result There were 66 (39.3%), 98 (58.3%), and 4 (2.4%) patients who were stratified into ALBI grade I, II, and III, respectively. Patients with ALBI grade II/III had older age (p = 0.002), hypoalbuminemia (p <0.001), and Child Pugh B (p = 0.009), they also had poor overall survival compared with those with ALBI grade I (p = 0.003). The patients without liver cirrhosis had better survival rate in ALBI grade 1 group (P = 4 0.012). In multivariate analysis, tumor number (p = 0.001) and tumor stages (pTNM stages) (p = 0.007) were independent prognostic factors for recurrence. In predictors for mortality, AFP (p = 0.004), ALBI grade (p = 0.004), tumor number (P=0.003) and tumor stages (pTNM stages) (p <0.001) were independent prognostic factors. Conclusion Preoperative ALBI grade can be used to predict the mortality in patients with NBNC-HCC after primary curative resection.
A comparative note on the ethnomedicinal plants used by the Kattunaikka and Paniya tribes of Nilambur forest, Malappuram district, Kerala, (India)
Authors: M CHITHRA , Pillai Geetha S 
Published: April 2021

Abstract
BackgroundAn ethnobotanical survey was conducted to explore the indigenous knowledge of the Kattunaikka and Paniya tribes of Nilambur forest, Malappuram District, Kerala, India and to highlight the uses of the diverse flora. Ethnobotanical inventory of an area contain raw data, abundant of idea and application of knowledge of certain people and it is an important area that deserves serious attention. This study aims to record the traditional knowledge of the tribal inhabitants Kattunaikka and Paniya of Malappuram district, Kerala state, India.MethodsData were collected through questionnaire survey, interviews with key informants (knowledgeable elders, religious leaders and other individuals), and field observations. Interviews and discussions were conducted in Malayalam (the local language) using a checklist of topics. The collected specimens were cross-checked for their local names with the help of key informants and development agents. The specimens are preserved in the CMPR Herbarium. Medicinally important parts of some plants were collected and preserved in Formalin Acetic Acid (FAA) solution for further reference. Each species were checked for its Ayurvedic uses with the help of available literature like Ayurvedic Pharmacopoeia of India and other books [13] and similarity and dissimilarity in uses were analysed.ResultsThis paper provides information about 79 medicinal plant species used by the two tribes to manage 38 ailments / conditions, either as single plant remedies or in combination. Of the 79 species recorded, 64 species (81%) were found to be used in the Ayurvedic system of medicine and 65% for similar conditions. One point of interest is that there was not even a single species commonly used by the two tribes as single plant remedy for a similar condition or ailment.ConclusionThe indigenous knowledge of these tribal traditional healers has been disappearing due to lack of followers for this valuable knowledge, as well as their migration to places outside of the forest. Use of plants among the two tribes reflects their interest in ethno-medicine and further investigation on under-explored species may lead to the discovery of novel pharmaceutical products.
Whose responsibility is it to address the needs of persons with mental health problems? Development of a scale to assess how stakeholders distribute responsibilities across geo-cultural contexts
Authors: Iyer Srividya , Pope Megan , Taksal Aarati , Mohan Greeshma , Rangaswamy Thara , Loohuis Heleen , Shah Jai , Joober Ridha , Schmitz Norbert , Ramachandran Padmavati , Malla Ashok 
Published: April 2021

Abstract
Background

Individuals with mental health problems have multiple, often inadequately met needs. Responsibility for meeting these needs frequently falls to patients, their families/caregivers, and governments. Little is known about stakeholders' views of who should be responsible for these needs and there are no measures to assess this construct. This study’s objectives were to present the newly designed Whose Responsibility Scale (WRS), which assesses how stakeholders apportion responsibility to persons with mental health problems, their families, and the government for addressing various needs of persons with mental health problems, and to report its psychometric properties.
Methods

The 22-item WRS asks respondents to assign relative responsibility to the government vis-à-vis persons with mental health problems, government vis-à-vis families, and families vis-à-vis persons with mental health problems for seven support needs. The items were modelled on a World Values Survey item comparing the government’s and people’s responsibility for ensuring that everyone is provided for. We administered English, Tamil, and French versions to 57 patients, 60 family members, and 27 clinicians at two early psychosis programs in Chennai, India, and Montreal, Canada, evaluating test-retest reliability, internal consistency, and ease of use.
Results

Test-retest reliability (intra-class correlation coefficients) ranged from excellent to good across stakeholders (patients, families, and clinicians); settings (Montreal and Chennai), and languages (English, French, and Tamil). Internal consistency estimates (Cronbach’s alphas) ranged from acceptable to excellent. The WRS scored average on ease of comprehension and completion. Scores were spread across the 1–10 range, suggesting that the scale captured variations in views on how responsibility for meeting needs should be distributed. On select items, scores at one end of the scale were never endorsed, but these reflected expected views about specific needs (e.g., Chennai patients never endorsed patients as being substantially more responsible for housing needs than families).
Conclusions

The WRS is a promising measure for use across geo-cultural contexts to inform mental health policies, and to foster dialogue and accountability among stakeholders about roles and responsibilities. It can help researchers study stakeholders’ views about responsibilities, and how these are shaped by and shape sociocultural contexts and mental healthcare systems.
Characteristics of General Soils, Natural Saltlicks and Artificial Saltlicks for Wild Asian Elephants (Elephas Maximus) Conservation in the Western Forests of Thailand
Authors: Chaiyarat Rattanawat , Kanthachompoo Salisa , Thongthip Nikorn , Yuttitham Monthira 
Published: April 2021

Abstract
Saltlicks are a keystone resource of wildlife. This study aimed to compare the characteristics among general soil, natural saltlicks and artificial saltlicks in the natural forest of Salakphra Wildlife Sanctuary (SWS) and restoration habitat for elephant (Elephas maximus) in Kui Buri National Park (KNP), western Thailand. Twenty general soils, 33 natural and 35 artificial saltlicks were analyzed. The chemical compositions in natural saltlicks were not consistent. The K, Mg, Fe and Cu in natural saltlicks were higher than artificial saltlicks in both areas. The Ca and Zn in artificial saltlicks in SES were higher than natural saltlicks of KNP. The salinity in artificial saltlicks was highest and higher than in natural saltlicks in both areas and can provide supplemental Na, thereby increasing salinity in both areas. The artificial saltlicks cannot provide Ca, K, Mg, Fe and Cu when compared to natural saltlicks that can provide a primary target for elephants at these sites. The findings have consequences for conservation of elephants and other large herbivores by supplementing essential macro- and micro-nutrients in artificial saltlicks. The key resources can provide information to help maintain the wildlife health and fecundity of the region.
Impact of boron and indium doping on the structural, electronic and optical properties of SnO2
Authors: Filippatos Petros-Panagis , Kelaidis N , Vasilopoulou Maria , Davazoglou Dimitris , Chroneos Alexander 
Published: April 2021

Abstract
Tin dioxide (SnO2), due to its non-toxicity, high stability and electron transport capability represents one of the most utilized transition metal oxides in many optoelectronic devices such as photocatalytic devices, photovoltaics (PVs) and light-emitting diodes (LEDs). However, its wide bandgap reduces its charge carrier mobility and its photocatalytic activity. Doping with various elements is an efficient and low-cost way to decrease SnO2 band gap and maximize photocatalytic applications' potential. Here, we apply density functional theory calculations to examine the effect of p-type doping with B and In of SnO2 on its electronic and optical properties. Calculation predict the creation of shallow energy states in the band gap, near the valence band, when the dopant (B or In) is in interstitial position. In the case of substitutional doping, a significant decrease of the band gap is calculated. We also investigate the effect of doping on the surface sites of SnO2. We find that B incorporation in the (110) does not alter the gap while In causes a notable decrease. The present work highlights the significance of boron and indium doping in SnO2 both for solar cells and photocatalytic applications.
Serum IgG4 Levels at Diagnosis Can Predict Unfavorable Outcomes of Untreated Patients With IgG4-related Disease: A Japanese Single-Center Retrospective Study
Authors: Mizushima Ichiro , Konishi Masahiro , Sanada Hajime , Suzuki Kazuyuki , Takeji Akari , Zoshima Takeshi , Hara Satoshi , Ito Kiyoaki , Fujii Hiroshi , Yamada Kazunori , Kawano Mitsuhiro 
Published: April 2021

Abstract
Background

The outcomes of patients with IgG4-RD who are not treated are unclear. This study aimed to clarify these outcomes and identify the factors related to them.
Methods

We retrospectively evaluated various clinical features including laboratory data and involved organs at diagnosis in 107 patients with IgG4-RD, who were followed up for more than 6 months, at a single center in Japan. We compared the clinical features of the 27 untreated patients with those of the 80 patients treated with glucocorticoid. The patient outcomes were investigated, and logistic regression analysis was performed to identify factors related to them.
Results

The patients comprised 73 men and 34 women (median age 67 years). The untreated patients had significantly lower IgG4-RD responder index (9 vs 12) and fewer affected organs (1 vs 3) than did those treated with glucocorticoid. Of these 27 patients, 8 experienced deterioration of IgG4-RD after the diagnosis. In the age- and sex-adjusted logistic regression analysis, serum IgG4 elevation (per 100 mg/dL, odds ratio 1.194, 95% confidence interval 1.017–1.402) was the only significant factor related to disease deterioration in untreated patients with IgG4-RD, whereas not serum IgG4 levels (per 100 mg/dL, odds ratio 0.995, 95% confidence interval 0.921–1.075) but history of allergy (OR 3.134, 95% confidence interval 1.094–8.977, P = 0.033) related to deterioration in patients who underwent treatment.
Conclusions

Serum IgG4 levels may be a useful predictor of unfavorable outcomes in untreated patients with IgG4-RD, who tend to have fewer affected organs and lower IgG4-RD responder index.
Dietary Inflammatory Potential and Risk of Breast Cancer: A Population-based Case-control Study in France (CECILE Study)
Authors: Hajji-Louati Mariem , Cordina-Duverger Emilie , Laouali Nasser , Mancini Francesca-Romana , Guénel Pascal 
Published: April 2021

Abstract
Background: Dietary regimens promoting inflammatory conditions have been implicated in breast cancer development, but studies on the association between pro-inflammatory diet and breast cancer risk have reported inconsistent results. Methods: We investigated the association between the inflammatory potential of diet and breast cancer risk in a case-control study in France including 872 breast cancer cases and 966 age-matched population controls. All women completed a food frequency questionnaire that was used to compute a Dietary Inflammatory Index (DII) based on the inflammatory weight of 33 dietary components. Results: The DII ranged from a median of -3.22 in the lowest quartile (anti-inflammatory) to +2.96 in the highest quartile (pro-inflammatory). The odds ratio contrasting quartile 4 to quartile 1 was 1.31 (95%CI: 1.00, 1.73; p -trend=0.02). Slightly higher odds ratios were observed in post-menopausal women, particularly those with body mass index >25kg/m 2 (odds ratio 1.62; 95%CI: 0.92, 2.83; p -trend=0.02), and among ever smokers (odds ratio 1.71; 95%CI: 1.11, 2.65; p-trend 0.01). The analyses by breast cancer subtype showed that the DII was associated with breast tumors that expressed either the estrogen (ER) or progesterone (PR) hormone receptors or the Human Epidermal Growth Factor Receptor-2 (HER2), but no association was seen for the triple negative breast tumor subtype. Conclusion: Our results add further evidence that a pro-inflammatory diet is associated with breast cancer risk with possible effect variation according to tumor subtype.
A Study On Increasing The Speed Limit of Axial Piston Pumps By Optimizing The Suction Duct
Authors: Fang Yu , Zhang Junhui , Xu Bing , Huang Chang-sheng , Lyv Fei , Guo Zhimin 
Published: April 2021

Abstract
The maximum delivery pressure and the maximum rotational speed determine the power density of axial piston pumps. However, increasing the speed beyond the limit always accompanies cavitation, leading to the decrease of the volumetric efficiency. The pressure loss in the suction duct is considered a significant reason for the cavitation. Therefore, this paper proposes a methodology to optimize the shape of the suction duct aiming at reducing the intensity of cavitation and increasing the speed limit. At first, a computational fluid dynamics (CFD) model based on the full cavitation model (FCM) is developed to simulate the fluid field of the axial piston pump and a test rig is set to validate the model. Then the topology optimization is conducted for obtaining the minimum pressure loss in the suction duct. Comparing the original suction duct with the optimized one in the simulation model, the pressure loss in the suction duct gets considerable reduction, which eases the cavitation intensity a lot. The simulation results prove that the speed limit can increase under several different inlet pressures.
Event-triggered Prescribed Settling Time Consensus Control of Uncertain Nonlinear Multiagent Systems with Transient Performance
Authors: Chen Zicong , Wang Jianhui , Zhang Li , Ma Kemao , Liu Yanhui 
Published: April 2021

Abstract
Multiagent systems are often applied in unmanned aerial vehicle formations, multi-manipulator coordinated, traffic vehicle control and other fields, which have attracted a lot of attention from scholars. In this paper, considering the given transient performance of multiagent systems, its synchronization error converges to the predefined interval by designing the performance function. In the meanwhile, through the designed nonlinear transformation of synchronization error, a prescribed setting time tracking control is realized, which can ensure that the multiagent systems are uniformly bounded convergent. In addition, event-triggered strategy is introduced to economize the utilization of multiagent systems' communication resources. Finally, theoretical analysis and simulation research demonstrates the effectiveness of the proposed method.
Development of Markers for Identification and Maker-Assisted Breeding of Xa7&nbsp;Gene in Rice (Oryza sativa&nbsp;L.)
Authors: Liu Pengcheng , Mei Le , He Lumei , Xu Yiling , Zhang Yiting , Zeng Dali , Zhang Xiaoming , Qian Qian , Chen Xifeng , Ma Bojun 
Published: April 2021

Abstract
Utilization of resistance (R) genes to breed resistant cultivars is one of the most effective and economical approach to control rice bacterial blight (BB). Xa7, a dominant, broad-spectrum and durable BB-resistant gene, is an ideal gene resource to improve the resistance of rice varieties to bacterial blight, and this well-known gene with important breeding value has been cloned in our recent study. The isolation of Xa7 will facilitate its application in rice breeding by molecular maker-assisted selection (MAS). In this study, based on the specific sequences in the promoter of Xa7, a functional marker, named as MX7, was developed, which can effectively distinguish the dominant BB-resistant Xa7, the recessive BB-susceptible xa7 and the null allele from different rice varieties. Since MX7 is a dominant marker, it can't tell homozygous from heterozygous, a co-dominant marker closely linked to Xa7, named as M6, was developed simultaneously. After verified by amplification in numerous rice varieties and sequence alignment in RICE 3K database, it is proved that marker M6 is co-segregated with the Xa7 locus. In addition, the effectiveness and accuracy of the two markers were further validated by two F2 populations. Finally, the designed makers were effectively applied in MAS breeding to improve the BB-resistance of a susceptible variety. This study not only provides reliable functional markers for the identification of Xa7 gene in different rice materials, but also will contribute to the application of Xa7 gene in marker-assisted selection to breed rice varieties with durable disease resistance.
Lead Induced, VDR Taq and MAO-A Associated Energy Metabolism Reduction, and CD4+CD3+ Lymphocytes-Dependent Inflammation as Main Pathogenetic Events in Autism Spectrum Disorders
Authors: Harutyunyan Aida A , Harutyunyan Hayk A , Yenkoyan Konstantin B 
Published: April 2021

Abstract
Background

Autism Spectrum Disorder (ASD) is characterized by persistent deficits in social communication and interaction and restricted-repetitive patterns of behavior, interests, or activities. ASD is generally associated with chronic inflammatory states, which are linked to immune system dysfunction and/or hyperactivation. The latter might be considered as one of the factors damaging neuronal cells. Several cell types trigger and sustain such neuroinflammation.
Methods

In this study, we traced different markers of immune system activation on both cellular (immune cell phenotypes) and mediatory levels (production of cytokines) alongside adverse hematology and biochemistry screening in a group of autistic children. In addition, we analyzed the main metabolic pathways potentially involved in ASD development – energy (Krebs cycle components), porphyrin and neurotransmitter metabolism. Several ASD etiological factors like heavy metal intoxication and risk factors – genetic polymorphisms of the relevant neurotransmitters and vitamin D receptors were also analyzed. Finally, broad linear regression analysis allowed us to elucidate the possible scenario that led to the development of chronic inflammation in ASD patients.
Results

Our data strongly support the lead induced, VDR Taq and MAO-A associated mitochondrial dysfunction, and CD4 + CD3 + T-cell dependent immune system activation and chronic inflammation as the key pathogenetic events in autism spectrum disorders. Moreover, our data supports the CD4 + CD3 + T-cell dependence of mitochondrial dysfunction development in ASD patient reported in our previous study.
Limitations

Difficulties to obtain target biological material (in this case cerebrospinal fluid, CSF) from autistic children under the age of 6 years and the small population of such patients limited our data from the qualitative and quantitative points of view. Nevertheless, the huge range of complex and target measurements has done partially overlap this flaw.
Conclusions

We come to the conclusion that redox-immune cross-talk is considered a main functional cell damaging factor in ASD patients.