bluuebunny/crossref_metadata_2025_split huggingface dataset:
Key Signatures of Magnetofossils Elucidated by Mutant Magnetotactic Bacteria and Micromagnetic Calculations
Authors: Amor Matthieu , Wan Juan , Egli Ramon , Carlut Julie , Gatel Christophe , Andersen Ingrid Marie , Snoeck Etienne , Komeili Arash 
Published: December 2021

AbstractMagnetotactic bacteria (MTB) produce single‐stranded or multi‐stranded chains of magnetic nanoparticles that contribute to the magnetization of sediments and rocks. Their magnetic fingerprint can be detected in ancient geological samples and serve as a unique biosignature of microbial life. However, some fossilized assemblages bear contradictory signatures pointing to magnetic components that have distinct origin(s). Here, using micromagnetic simulations and mutant MTB producing looped magnetosome chains, we demonstrate that the observed magnetofossil fingerprints are produced by a mixture of single‐stranded and multi‐stranded chains, and that diagenetically induced chain collapse, if occurring, must preserve the strong uniaxial anisotropy of native chains. This anisotropy is the key factor for distinguishing magnetofossils from other populations of natural magnetite particles, including those with similar individual crystal characteristics. Furthermore, the detailed properties of magnetofossil signatures depend on the proportion of equant and elongated magnetosomes, as well as on the relative abundances of single‐stranded and multi‐stranded chains. This work has important paleoclimatic, paleontological, and phylogenetic implications, as it provides reference data to differentiate distinct MTB lineages according to their chain and magnetosome morphologies, which will enable the tracking of the evolution of some of the most ancient biomineralizing organisms in a time‐resolved manner. It also enables a more accurate discrimination of different sources of magnetite particles, which is pivotal for gaining better environmental and relative paleointensity reconstructions from sedimentary records.
Near‐Surface Geomechanical Properties and Weathering Characteristics Across a Tectonic and Climatic Gradient in the Central Nepal Himalaya
Authors: Medwedeff William G. , Clark Marin K. , Zekkos Dimitrios , West A. Joshua , Chamlagain Deepak 
Published: December 2021

AbstractShallow bedrock strength controls both landslide hazard and the rate and form of erosion, yet regional patterns in near‐surface mechanical properties are rarely known quantitatively due to the challenge in collecting in situ measurements. Here we present seismic and geomechanical characterizations of the shallow subsurface across the central Himalayan Range in Nepal. By pairing widely distributed 1D shear wave velocity surveys and engineering outcrop descriptions per the Geological Strength Index classification system, we evaluate landscape‐scale patterns in near‐surface mechanical characteristics and their relation to environmental factors known to affect rock strength. We find that shallow bedrock strength is more dependent on the degree of chemical and physical weathering, rather than the mineral and textural differences between the metamorphic lithologies found in the central Himalaya. Furthermore, weathering varies systematically with topography. Bedrock ridge top sites are highly weathered and have S‐wave seismic velocities and shear strength characteristics that are more typical of soils, whereas sites near valley bottoms tend to be less weathered and characterized by high S‐wave velocities and shear strength estimates typical of rock. Weathering on hillslopes is significantly more variable, resulting in S‐wave velocities that range between the ridge and channel endmembers. We speculate that variability in the hillslope environment may be partly explained by the episodic nature of mass wasting, which clears away weathered material where landslide scars are recent. These results underscore the mechanical heterogeneity in the shallow subsurface and highlight the need to account for variable bedrock weathering when estimating strength parameters for regional landslide hazard analysis.
Late Cretaceous Paleoceanographic Evolution and the Onset of Cooling in the Santonian at Southern High Latitudes (IODP Site U1513, SE Indian Ocean)
Authors: Petrizzo Maria Rose , MacLeod Kenneth G. , Watkins David K. , Wolfgring Erik , Huber Brian T. 
Published: December 2021

AbstractThe latest Cenomanian to Santonian sedimentary record recovered at IODP Expedition 369 Site U1513 in the Mentelle Basin (SE Indian Ocean, paleolatitude 60°S at 85 Ma) is studied to interpret the paleoceanographic evolution in the Southern Hemisphere. The planktonic foraminiferal assemblage changes, the depth ecology preferences of different species, and the surface and seafloor temperature inferred from the stable isotopic values measured on foraminiferal tests provide meaningful information to the understanding of the Late Cretaceous climate. The hothouse climate during the Turonian‐Santonian, characterized by weak latitudinal temperature gradients and high atmospheric CO2 concentrations, is followed by a progressive cooling during the Campanian. At Site U1513 the beginning of this climatic transition is nicely recorded within the Santonian, as indicated by an ∼1‰ increase in δ18O values of planktonic foraminifera suggesting a decline in surface water paleotemperatures of 4°C. The onset of cooling is mirrored by changes in the planktonic foraminiferal assemblages including extinctions among surface and deep dwellers, appearances and diversification of newly evolving taxa, and changes from predominantly epifaunal oxic to infaunal dysoxic/suboxic taxa among co‐occurring benthic foraminifera. Overall, the data presented here document an interval in the Santonian during which the rate of southern high latitude cooling increased. Both surface and bottom waters were affected, although the cooling signal is more evident in the data for surface waters. This pattern of cooling ascribes the deterioration of the Late Cretaceous climate to decreased CO2 in the atmosphere and changes in the oceanic circulation correlated with enhanced meridional circulation.
An Efficient and Compact Monopole Antenna Backed With Square Loop EBG Structure for Medical Wireless Body Area Network Applications
Authors: Darabi Maryam , Mohajeri Farzad 
Published: December 2021

AbstractIn this paper, a compact, low‐profile, and simple monopole antenna is presented that is operated at the frequency of 2.4 GHz in industrial scientific medical band. The monopole antenna is based on the simple rectangular microstrip patch with a rotated T‐shaped slot. Furthermore, a 2 × 2 electromagnetic band‐gap (EBG) array is used in this design to act as an isolator between the antenna and the human body, which additionally increases the performance of the proposed antenna. The final design has an overall size of only 0.9λg × 0.9λg × 0.034λg (60 × 60 × 2.3 mm3) where λg is the guided‐wavelength with respect to RO4003 substrate at the resonant frequency of 2.4 GHz. This can make the structure a good candidate for wireless body area network applications. A prototype of the designed EBG‐based antenna is fabricated over a widely available RO4003 substrate. The measurement results show a gain of 6.52 dBi, a front to back ratio of 12.12 dB, and a total efficiency of 79.87% around the resonant frequency. Furthermore, numerical studies are conducted to evaluate the specific absorption rate (SAR) of the proposed design, which shows by introducing the EBG structure, more than 96% reduction in SAR level is obtained. All simulations are carried out by CST microwave studio software.
From Stream Flows to Cash Flows: Leveraging Evolutionary Multi‐Objective Direct Policy Search to Manage Hydrologic Financial Risks
Authors: Hamilton Andrew L. , Characklis Gregory W. , Reed Patrick M. 
Published: December 2021

AbstractHydrologic variability can present severe financial challenges for organizations that rely on water for the provision of services, such as water utilities and hydropower producers. While recent decades have seen rapid growth in decision‐support innovations aimed at helping utilities manage hydrologic uncertainty for multiple objectives, support for managing the related financial risks remains limited. However, the mathematical similarities between multi‐objective reservoir control and financial risk management suggest that the two problems can be approached in a similar manner. This paper demonstrates the utility of Evolutionary Multi‐Objective Direct Policy Search for developing adaptive policies for managing the drought‐related financial risk faced by a hydropower producer. These policies dynamically balance a portfolio, consisting of snowpack‐based financial hedging contracts, cash reserves, and debt, based on evolving system conditions. Performance is quantified based on four conflicting objectives, representing the classic tradeoff between “risk” and “return” in addition to decision‐makers’ unique preferences toward different risk management instruments. The dynamic policies identified here significantly outperform static management formulations that are more typically employed for financial risk applications in the water resources literature. Additionally, this paper combines visual analytics and information theoretic sensitivity analysis to improve understanding about how different candidate policies achieve their comparative advantages through differences in how they adapt to real‐time information. The methodology presented in this paper should be applicable to any organization subject to financial risk stemming from hydrology or other environmental variables (e.g., wind speed, insolation), including electric utilities, water utilities, agricultural producers, and renewable energy developers.
Reservoir Attributes Display Cascading Spatial Patterns Along River Basins
Authors: Faucheux Nicky M. , Sample Andrew R. , Aldridge Caleb A. , Norris David M. , Owens Conner , Starnes Victoria R. , VanderBloemen Spencer , Miranda Leandro E. 
Published: December 2021

AbstractConsidering reservoirs as linear fragments in a basin's river network could improve understanding, predictability, and management efficiency. We looked for general cascading spatial patterns across five categories of reservoir attributes: land cover, morphology and hydrology, fish habitat, fish assemblages, and fisheries. Attributes were pulled from various databases for large reservoirs (>100 ha) located in the United States. 16 widely distributed river basins, each including a minimum of 15 large reservoirs, were selected for analysis. Using analysis of covariance with basin as the class variable, we tested each attribute as a linear function of catchment area, which is an index of reservoir position in the basin. The majority of reservoir attributes displayed log‐linear patterns as catchment area increased, indicating that reservoirs act as members of a larger network just as river reaches do. Several patterns were detected including attributes with no apparent lengthwise arrangement along the basin; cascading spatial patterns in which attributes increase or decrease from upstream to downstream within a basin; and attributes that increase with catchment area in some basins, decrease in others, or may simply remain constant throughout the basin. We conclude that each pattern may have different implications for management, and that the effectiveness with which most management activities influence reservoirs is likely to increase or decrease along river basins.
Facile synthesis of N-aryl phenothiazines and phenoxazines via Brønsted acid catalyzed C–H amination of arenes
Authors: Xia Wang , Zhou Zi-An , Lv Jie , Xiang Shao-Hua , Wang Yong-Bin , Tan Bin 
Published: December 2021

An organocatalytic C–H amination of azonaphthalenes with phenothiazines and phenoxazines has been established. N-naphthyl phenothiazine and phenoxazine structures which are of significance in various fields could now be accessed in high efficiency.
Investigation on insulation properties of HFO‐1336mzz(E) and N2/CO2 mixtures as SF6 substitutes in gas‐insulated electrical applications
Authors: Gao Zhanyang , Luo Yunbai , Peng Ruichao , Wang Xiaoxiao , Yu Ping , Zhou Wenjun 
Published: December 2021

AbstractThe emissions of SF6 have been restricted owing to 3400 years of atmospheric lifetime and high global warming potential (GWP) as an insulating gas in gas‐insulated electrical equipment. In this study, HFO‐1336mzz(E) and N2/CO2 mixtures are proposed as SF6 substitutes for their short atmospheric lifetime, low GWP and superior insulation performance. The GWP of HFO‐1336mzz(E) is only 18 and its atmospheric lifetime is days to weeks. The breakdown voltage of 25% HFO‐1336mzz(E) and N2/CO2 mixtures is about 85% that of pure SF6 under alternating current. The self‐recovery ability of HFO‐1336mzz(E) and CO2 mixtures is superior to that of HFO‐1336mzz(E) and N2 mixtures. The decomposition characteristic of HFO‐1336mzz(E) shows that a tiny amount of its gas might initiate a carbonisation reaction to form carbon after multiple breakdown tests, which is verified by observations using energy dispersive X‐rays spectroscopy and scanning electron microscope. The acute toxicity test of HFO‐1336mzz(E) indicates that the gas is non‐toxic. The results show that HFO‐1336mzz(E) and N2/CO2 mixtures are potential substitutes for SF6 in electrical applications.
Hochverarbeitete Lebensmittel und ihre Bedeutung für die Genese ernährungsmitbedingter Erkrankungen
Authors: Fedde Svenja , Rimbach Gerald , Schwarz Karin , Bosy-Westphal Anja 
Published: December 2021

ZusammenfassungHochverarbeitete Lebensmittel sind Teil eines modernen Lebensstils und machen in Deutschland ca. 46 % der täglichen Energieaufnahme aus. Querschnitts- und Kohortenstudien belegen Assoziationen zwischen dem Verzehr hochverarbeiteter Lebensmittel und nichtübertragbaren Erkrankungen (Übergewicht, Diabetes, Krebs, Herz-Kreislauf-Erkrankungen sowie Depressionen). Als Ursache für diesen Zusammenhang werden neben einer hohen Energiedichte und einer veränderten Lebensmittelmatrix eine ernährungsphysiologisch unausgewogene Zusammensetzung, ein hoher glykämischer Index, sowie abträgliche Zusatzstoffe und Kontaminanten durch Verarbeitung und Verpackung diskutiert. Um die anteilige Bedeutung dieser potenziellen Mechanismen zu verstehen und eine wissenschaftlich begründete, risikoassoziierte Definition hochverarbeiteter Lebensmittel zu geben, sind sowohl Interventionsstudien als auch eine bessere Erfassung der Zusammensetzung der verzehrten verarbeiteten Lebensmittel in prospektiven Kohortenstudien nötig.
Intermolecular correlations of liquid and glassy CS2 studied by synchrotron radiation x-ray diffraction
Authors: Mizuno Yuki , Zhao Yuansheng , Akiba Hiroshi , Kohara Shinji , Ohara Koji , Tucker Matthew G. , McDonnell Marshall T. , Yamamuro Osamu 
Published: December 2021

How is the orientation of molecular liquids ordered on cooling? What are the basic structures of molecular glasses, e.g., close to the crystalline structure or some special structures such as icosahedral cluster? These are long-standing questions in liquid and glass physics. We have constructed a novel cryostat to prepare simple molecular glasses by vapor deposition and performed in situ synchrotron radiation x-ray diffraction experiments. The glassy state of a simple molecule CS2, which cannot be vitrified by normal liquid quenching, was successfully prepared with this instrument, and its diffraction data were collected in a wide Q-range of 0.16–25.7 Å−1 with a high-energy diffractometer at BL04B2, SPring-8. The diffraction data of liquid CS2 were also recorded in a wide temperature range of 160–300 K. These diffraction data were analyzed with molecular dynamics simulations and reverse Monte Carlo modelings to investigate orientational correlation. From the obtained 3D structure models, the orientational correlation between neighboring CS2 molecules was investigated quantitatively as a function of temperature. At room temperature, the parallel and T-shaped arrangements are preferred for the nearest neighbor correlation. On cooling, these arrangements are developed gradually, and its rate became prominent below the melting temperature (162 K). In the glassy state, the slipped-parallel arrangement is dominant as well as the T-shaped arrangement. Both arrangements appear in the CS2 crystal, indicating that the structure of glassy CS2 is close to that of crystalline CS2.
Co-delivery of paclitaxel and doxorubicin using polypeptide-engineered nanogels for combination therapy of tumor
Authors: Yang Jie , Jin Rui-Mei , Wang Shen-Yan , Xie Xiao-Ting , Hu Wei , Tang Hong-Feng , Liu Bo 
Published: December 2021

Abstract
Loading of chemotherapeutic agents into nanoparticles has been demonstrated to be an effective strategy for cancer therapy. However, simultaneous delivery of different functional drugs to tumor sites for chemotherapy still remains challenging. In this study, nanogels formed by an engineered coiled-coil polypeptide PC10A were designed and prepared as a carrier for co-delivery of paclitaxel (PTX) and doxorubicin (DOX) through ultrasonic treatment and electrostatic adsorption. The drug loading content and encapsulation efficiency of PTX and DOX in the PC10A/PTX/DOX nanogels were 5.98 wt%, 70 wt%, and 8.55 wt%, 83 wt%, respectively. Because the polypeptide PC10A was non-toxic and biodegradable, the PC10A/PTX/DOX nanogels exhibited good biocompatibility. The in vitro and in vivo antitumor experiments showed that the PC10A/PTX/DOX nanogels possessed obviously synergistic therapy effect of tumors and lower side effects compared with free PTX/DOX. Therefore, the PC10A/PTX/DOX nanogels are promising to provide a new strategy for combination therapy of different functional drugs.
Adjusting the Benjamini–Hochberg method for controlling the false discovery rate in knockoff-assisted variable selection
Authors: Sarkar Sanat K , Tang Cheng Yong 
Published: December 2021

SummaryWe consider the knockoff-based multiple testing set-up of Barber & Candès (2015). for variable selection in multiple regression. The method of Benjamini & Hochberg (1995) and an adaptive version of it are adjusted to this set-up, transforming them to valid $p$-value-based, false discovery rate-controlling methods that do not rely on specifying the correlation structure of the explanatory variables. Simulations and real data applications show that the proposed methods are powerful competitors of the false discovery rate-controlling method of Barber & Candès (2015).
Brittle mineral prediction based on rock-physics modelling for tight oil reservoir rocks
Authors: Ba Jing , Hu Peng , Tan Wenhui , Müller Tobias M , Fu Li-Yun 
Published: December 2021

AbstractThe reservoir rocks from Chang-7 member of Yanchang Formation of Ordos Basin are characterised with heterogeneous fabric structures at the pore scale, and low porosity/permeability is exhibited at the macro scale. Precise prediction of reservoir brittleness is of great significance to oil production. Ultrasonic experiments are performed on tight sandstones collected from the target formation. A rock-physics model (RPM) is presented based on the Voigt–Reuss–Hill average (VRH), self-consistent approximation (SCA) and differential effective medium (DEM) theory. The brittleness characteristics relying on mineral composition, porosity and microcrack properties are explored by using the RPM. The Young's modulus increases and Poisson ratio decreases with increasing quartz content. Based on experimental, log and seismic data, brittle mineral analysis of rock physical model is performed at multiple scales. The model accuracy is verified by experimental data and well log data. The brittleness distribution is predicted on the basis of log and seismic data, which can be instructive for the reservoir rock fracturing in actual engineering operations.
Comparing Rheumatology Consultation Patterns Across Telehealth Platforms and Face-to-Face Clinic in the Military Health System
Authors: Loncharich Michael F , Desena David F , Collamer Angelique N , Edison Jess D 
Published: December 2021

ABSTRACT

Objective
To compare patterns of rheumatology consultations and outcomes across four different platforms in the Military Health System (MHS): face-to-face, synchronous telehealth, and two asynchronous telehealth platforms.

Methods
We conducted a retrospective review comparing face-to-face rheumatology consults during 2019 with teleconsultations from three virtual systems in the MHS: an asynchronous email-based system from May 2006 to Feb 2018, a web-based platform from 2014 to 2018, and synchronous telehealth consults from March 2020 to March 2021. Consults were reviewed for diagnosis, and if medical evacuation was required for consults originating OCONUS or if face-to-face follow-up was required for synchronous teleconsults. Diagnoses of interest included inflammatory arthritis, noninflammatory arthritis, crystalline arthritis, myositis, lupus, vasculitis, fibromyalgia, antibody positivity without diagnosis, symptoms without specified diagnosis, and a composite of other rheumatic diseases.

Results
Leading diagnoses across platforms were inflammatory arthritis, noninflammatory arthritis, and a composite of other diagnoses. Consultation modality influenced the type of cases seen. Inflammatory arthritis accounted for significantly more consults in the synchronous telehealth (38.4%) and email-based (40.9%) models than in the web-based (23.7%) and face-to-face (32.0%) models. The composite of other diagnoses was the leading diagnosis for the asynchronous web-based model (32.9%), which was significantly more than the synchronous telehealth and face-to-face consults. Synchronous models saw significantly more cases of crystalline arthritis, vasculitis, and fibromyalgia.
Email-based consultations resulted in medical evacuation in 25 cases and prevented evacuation in 5. Web-based consultations prompted medical evacuation in 100 cases. In the synchronous model, face-to-face follow-up was recommended in 142 (15%) cases.

Conclusions
Modality of consultation influences the type of cases seen. Both synchronous and asynchronous telerheumatology models were able to answer the consult question without referral for face-to-face evaluation in 79.9-85.0% of consults, suggesting teleconsultation is a viable method to increase access to high-quality rheumatology care.
Extensive triple vessel coronary artery disease in a young male with juvenile idiopathic arthritis
Authors: Tsabedze Nqoba , Seboka Mpoti , Mpanya Dineo , Solomon Ahmed 
Published: December 2021

ABSTRACT
The risk of cardiovascular disease in patients with chronic inflammatory joint conditions is substantially increased compared to the general population. We present a case of a 27-year-old male with a chronic history of juvenile idiopathic arthritis (JIA) who presented with denovo acutely decompensated chronic heart failure. He had no traditional risk factors for atherosclerotic cardiovascular disease (ASCVD). However, during his workup for dilated cardiomyopathy, he was found to have extensive triple vessel disease on coronary artery angiography, and this was subsequently thought to be the most likely aetiology for the dilated cardiomyopathy despite being of young age. The chronic JIA was identified as the principal risk factor for the ischaemic cardiomyopathy. Clinicians treating patients with rheumatological conditions should routinely screen for ASCVD, despite the absence of traditional cardiovascular risk factors.