bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamic characteristics of students’ communicative behavior in social networks
Authors: Nikishina Vera B. , Sokolskaya Marina V. , Musatova Oksana A. , Zapesotskaya Irina V. , Danilova Alina V. , Balykina Anna М. 
Published: November 2021

Dynamic characteristics of social networks users' behavior represent the toolkit for diagnosing the character and orientation of cyber communication. This study aims to analyze the communicative behavior of youth after transitioning directly from direct communication to communication via technology for the purpose of defining opportunities and determining manipulation potential on communicants. Sixty-two (62) active participants of social networks were selected to answer the questions of the questionnaire. Further, on the grounds of the provided statistics of their accounts, quantitative characteristics of dynamics of cyber communication of participants' communicative behavior were analyzed using descriptive statistics and r-criterion of Spearman rank correlation. From the results, decrease in the level of intellectual communication of the youth in cyberspace provides a high level of the youth manipulative availability in social networks. Hypotheses about measurability of dynamic characteristics of cyber communication, as well as the communication vector shift from small groups into big ones were confirmed.
Keywords: dynamic characteristics of communication, cyber communication, social networks, meme, repost, post.
Video and media technologies in the educational space as a form of mental representation of students of different cultures
Authors: Zvonova Elena V. , S. Babieva Nigina , Mamedova Alisa V. , Tarabakina Lyudmila V. , Pestereva Nikol A. , Kerimova Izumrud A. 
Published: November 2021

The search for conditions to create a developing learning environment, methods and means of teaching is the main objective of psychological science. The relevance of the problem under study is due to the active development of intercultural communication processes, in which advertising plays an important role. This circumstance requires the inclusion of video and media technologies in the training of specialists in the field of advertising. The purpose of the paper is to describe the course and the results of the study of imaginal representations in advertising aimed at promoting goods in different cultures. The leading method in the study of this problem was the semantic differential which allows one to identify the difference in the semantic content of the commercial of a popular drink produced by an international company. Fifty students who are representatives of religious and non-religious cultures, aged between 18 and 30 participated in the study. The authors of the paper put forward the assumption that since social representations are formed and depicted in different cultures which are different from the social representations of other cultures, the content of the advertising text will be interpreted in different ways. This can affect people’s behavior of different cultures. The content of imaginal representations was studied in the process of perceiving the advertisement of a popular drink. The results of the study showed a significant difference in the content of imaginal representations of the experimental groups. However, the study showed that this difference did not influence consumers’ behavior. The materials of the paper may be useful for psychologists studying intercultural differences, as well as specialists in advertising psychology, when developing advertising texts for multicultural goods and services.
Keywords: video and media technologies, imaginal representations, advertisement, culture, types of cultures, behavior.
Enhancement of Educators’ Digital Competences in the Acquisition Programming Fundamentals in Programming Environment Scratch
Authors: Medveckis Arturs , Pigozne Tamara , Tomsons Dzintars 
Published: November 2021

Life-long learning, including development of professional competence, is an essential paradigm of the 21st century. The goal of this research is to analyse the quality and efficiency of the educators’ professional competence enhancement programme dubbed “Fundamentals of Programming in Visual Programming Environment Scratch” in accordance with the following criteria: organization, lecturer’s competence, quality of handouts, content, expectations, usefulness, applicability, and the overall assessment of the programme. The target group of the research is 98 educators of Latvia. Data was collected using close and open questions to ensure triangulation of data. Results were analysed using SPSS 20. The correlation coefficient was used to analyse the data. Per the results of the analysis, the acquisition of the professional competence enhancement programme, educators have significantly improved their knowledge in programming, as well as the digital competence in general
Keywords: educators’ professional competence; digital competence; fundamentals of programming; programming environment; Scratch.
Digitalization in international and mass education: A model proposal for Turkey
Authors: Gezici Hikmet Salahaddin , Taşpınar Yasin , Kocaoglu Mustafa 
Published: November 2021

There is a debate as to whether internationalization should be a target or a means to achieve goals with broader perspectives. Digitalization, on the other hand, is a de facto trend that permeates all communicative, economic and social areas. For this purpose, the study aimed to examine literature on the field and the findings of the researchers on the issue were included. The research also discussed the internationalization and digitalization efforts carried out in the world and in Turkey. An internationalization model proposal for the Turkish higher education system is presented in outline, taking the best practices around the world into account. Model involves a digitalization-oriented education approach that aims to increase the opportunities for students to get support from their families and to minimize their socio-economic difficulties. The contributions of a massification provided by digitalization to international education have been revealed in this study.
Keywords: digitalization; education; internationalization; massification; Turkey.
PROPERTIES OF BOILER FUEL COMPOUNDED BY NARROW FUEL FRACTIONS
Authors: Shevchenko K. , Grigorov A. , Sinkevich I. 
Published: November 2021

In order to improve the performance properties, in particular viscosity-temperature, of boiler fuel, it is proposed to combine them with narrow fuel fractions obtained by thermal destruction of secondary polymer raw materials (low pressure polyethylene and polypropylene).
When compounding grade 100 fuel oil with narrow fuel fractions, the values ​​of density are reduced to 865 (873) kg / m3, conditional viscosity to 2.50 (2.63) deg. um., pour point up to 8 (13) °C), sulfur content up to 0.17 wt%. and the lower heat of combustion increases to 43606 (43850) kJ / kg. At the same time, there is a gradual decrease in the value of the flash point to 114 (127) °C.
This reduction is a negative point, which leads to increased fire safety of fuel oil during its use, storage, pumping and transport. However, the values of the flash point, according to the requirements of regulatory documentation, are within acceptable limits. That is, the value of this indicator can limit the content of fuel oil in narrow fuel fractions.
It is determined that the rational concentration of narrow fuel fractions in the composition of fuel oil grade 100, is within 30% of the mass. Within these limits, there is a permissible decrease in flash point values – an indicator that characterizes the fire hazard of fuel oil during its use, storage, pumping and transportation against the background of improving other performance properties of fuel oil.
The production of the proposed compound boiler fuel on the one hand allows to expand the raw material base of the process by involving in the production process secondary polymer raw materials – solid waste subject to mandatory disposal, on the other – to meet existing demand for boiler fuel by increasing its production.
HEAT FLOWS INTEGRATION OF DISTILLATION AND EPURATION COLUMNS INTO THE PRODUCTION PROCESS OF RECTIFIED ETHYL ALCOHOL
Authors: Riabova I. , Hariev A. , Hariev L. , Gorbunov K. 
Published: November 2021

Today, ethyl alcohol is widely used in many industries. Ethanol production processes from any organic matter often involve rectification, which is an energy-intensive process. The constant increase in the cost of energy leads to a significant growth of the cost of production. Reducing the unit energy consumption can solve a range of important issues: first, that of decreasing production cost, and secondly, that of nationwide dependence on external energy suppliers. A detailed analysis of the thermal energy potential of technological flows aimed at solving the problem of reducing energy consumption inspires the development of more energy-efficient solutions for organizing this processes.
The search for alternative solutions demonstrates that one of the methods of reducing the unit energy consumption for ethanol production, in particular one that does not require a total restructuring of the production lines, is the method of integration of processes based on pinch analysis.
The extraction of these technological flows was carried out on the basis of the regulatory documentation of the hardware-technological scheme of the centralized ethyl alcohol head fraction distillation plant and the energy audit report of that plant, which was carried out at one of the alcohol enterprises of Ukraine.
A distillation and a purification column were selected from the centralized ethyl alcohol distillation plant for thermal integration of the existing process. The thermal and material balances of the ethyl alcohol head fraction distillation plant columns were calculated.
To maximize the energy potential of the heat flows, the principles of pinch design were applied and a grid diagram of heat exchanger networks was designed.
To maximize the recovery of thermal energy, the difference ΔTmin was set to - 3ºC. This led to the need to use energy-efficient heat exchange equipment. A significant reduction in the use of external utilities (by 48% for cold utilitie and by 38% for hot utilitie) for selected heat flows and a short payback period for the project (approximately three months) makes this solution viable.
Eﬀect of the combination of theophylline and budesonide on production of proinﬂammatory cytokines by blood cells of patients with chronic obstructive pulmonary disease
Authors: Kadushkin A. G. , Taganovich A. D. , Movchan L. V. , Talabaeva E. I. , Plastinina A. V. , Shman T. V. 
Published: November 2021

The objective: to evaluate the ability of the combination of theophylline and budesonide to suppress proinﬂammatory cytokine production byblood cells in patients with chronic obstructive pulmonary disease (COPD).Subjects and Methods. Peripheral blood mononuclear cells (PBMCs) or whole blood cells of COPD patients (n = 27) were incubated with budesonide (10 nM), theophylline (1 μM), or the combination thereof and stimulated with phytohemagglutinin (PHA) or phorbol myristate acetate (PMA) and ionomycin. The enzyme immunoassay was used to evaluate the secretion of thymic stromal lymphopoietin (TSLP), macrophage migration inhibitory factor (MIF), interleukin 17A (IL-17A), IL-33, and other mediators of PBMC cells, and induced PHA. The ﬂow cytometry was used to analyze intracellular production of proinﬂammatory cytokines stimulated by PMA/ionomycin in T-helpers (CD4+) and cytotoxic T-lymphocytes (CD8+).Results. Theophylline reduced the secretion of IL-4 and IL-17A by PBMC cells. The combination of budesonide with theophylline inhibited the synthesis of IL-4, IL-5, IL-8, IL-13, IL-17A, IL-33, TSLP, MIF by PBMC cells as well as the production of IL-4, IL-8, tumor necrosis factor-α, and interferon-γ by cytotoxic T-lymphocytes and T-helpers. The combination of theophylline and budesonide had a more pronounced inhibitory eﬀect on the production of IL-4 and IL-8 by PBMC cells as well as the synthesis of IL-4 by CD4+ T-cells and IL8 by CD8+ T-lymphocytes versus the eﬀect of monotherapy with budesonide.
Surgical treatment of patients with HIV-associated respiratory tuberculosis and diﬀerent immune status
Authors: Shugaeva S. N. , Suzdalnitskiy A. E. , Savilov E. D. 
Published: November 2021

The objective of the study: to evaluate the impact of HIV infection on the nature and results of surgical interventions in respiratory tuberculosis (RTB) patients with the relevance of their immune status.Subjects and Methods. An ambispective observational study with continuous sampling included 565 patients above 18 years old who underwent surgical interventions. The study participants were divided into RTB+HIV Group (90 patients) with HIV-associated respiratory tuberculosis and RTB Group which included 475 HIV negative patients with respiratory tuberculosis. In RTB+HIV Group, patients were divided into three subgroups: with CD4-lymphocyte count below 200 cl/μL (n = 41), 200-499 cl/μL (n = 26), and 500 or more cl/μL (n = 23).Results. Compared to RTB Group, RTB+HIV Group was found to have less frequent resection surgery (24%; p < 0.0001; OR = 3.0) with acomparable frequency of collapsed surgery (4%; p > 0.05) and much more frequent thoracic diagnostic surgery (11%; p < 0.0001; OR = 10.6) and extrathoracic surgery (50%; p < 0.0001; OR = 6.8). In RTB+HIV Group, patients with CD4-lymphocyte count below 200 cells/μL (46%; p < 0.05) who had no resection surgery predominated, and the rate of collapsed surgery was 2.4% (p < 0.0001). There were no statistically signiﬁcant diﬀerences in the incidence of postoperative complications for each individual type of surgery when stratifying participants by CD4-lymphocyte count in the intergroup comparison, as well as in RTB+HIV Group.
Comparison of variants of anesthesia for left atrial appendage occlusion in patients with atrial fbrillation
Authors: Pevzner D. V. , Merkulova I. A. , Alieva A. K. , Gadzhibekov N. Ch. , Avetisyan E. A. , Kochergin N. A. , Ganyukov V. I. 
Published: November 2021

Objective: comparison of general anesthesia (GA) and intravenous conscious sedation during left atrial appendage occlusion (LAAO).Materials and Methods. The study included 120 patients from LAAO Register at the National Medical Research Center of Cardiology, who were divided into GA (n = 100) and intravenous sedation (n = 20) groups. In-hospital outcomes were assessed, as well as outcomes and data of transesophageal echocardiography (TEE) at 45 days and 6 months.Results. 3 patients required intraoperative conversion of the anesthetic method to GA. The duration of the procedure, the time of ﬂuoroscopy, the amount of contrast medium, and the technical success did not diﬀer signifcantly between the two groups. The incidence of in-hospital complications in the GA group was 10%, and 15% in the intravenous sedation group (p = 0.453). There were no statistically signifcant diﬀerences between the groups in long-term outcomes and TEE data after 45 days and 6 months.Conclusion. Combined intravenous sedation with local anesthesia is an eﬀective and fairly safe method of anesthesiological support for implantation of the occluder of the left atrial auricle. It can be used in patients with a high risk of GA, with predictable difculties of tracheal intubation, as well as if the patient wishes accordingly. The limitations of the use of intravenous sedation in combination with local anesthesia are anatomical variants of SFM that are difcult for occluder implantation, as well as the patient's low tolerance to ECG in consciousness.
Nosocomial meningitis laboratory criteria in ICU patients: 5-year surveillance
Authors: Kurdyumova N. V. , Usachev D. Yu. , Savin I. A. , Ershova O. N. , Gadzhieva O. A. , Shifrin M. A. , Danilov G. V. , Burov A. I. 
Published: November 2021

Introduction. Nosocomial meningitis (NM) is one of the leading complications in neurosurgery due to high mortality and disability rates.Objective. The study was aimed to determine the reference values of laboratory parameters to diagnose NM in neurosurgical patients in the intensive care unit (ICU).Results. The incidence of NM in neurosurgical patients in ICU was 8.4 (95% CI 6.8–10. 0) per 100 patients. The dominant microbial agents of NM were coagulase-negative staphylococci, A. baumannii, and K. pneumoniae. We revealed the increase in leukocytosis, C-reactive protein, and blood procalcitonin in patients with infectious complications of other systems, regardless of NM presence. Episodes of hyponatremia and an increase in body temperature ≥ 38.0 occurred signifcantly more often in patients with NM. Changes in cerebrospinal ﬂuid (CSF) cytosis, glucose, lactate, and the CSF/blood glucose ratio can serve as reliable criteria in the NM diagnosis.Conclusions. The diagnosis of NM is most likely when the increase in CSF cytosis > 65 cells/μL, CSF lactate > 4.2 mmol/L is observed, the decrease in the CSF glucose < 2.6 mmol, and CSF/blood glucose ratio < 0.45 is found.
Associations of molecular genetic predictors of type 2 diabetes mellitus with hyperglycemia in extremely low birth weight infants
Authors: Mironov P. I. , Mingazov N. N. , Valiev R. R. , Lekmanov А. U. 
Published: November 2021

Hyperglycemia in premature newborns is an independent risk factor for death, so blood glucose testing is widely used in the practice of neonatal intensive care units.Objective: to evaluate the associations of the frequency of carriage of allelic variants of polymorphic loci of genes predisposing to type 2 diabetes mellitus in newborns with extremely low body weight and hyperglycemia.Methods. The study design is prospective, controlled, single – center, non-randomized. Genomic DNA samples were studied in newborn infants with extremely low body weight (ELBW) (n = 105). Previously, we compared the distribution of allele frequencies of the studied genes between a group of newborns with ELBW and a population sample of adults (control). Then, the distribution of allele frequencies of the genes was compared depending on the presence of hyperglycemia in newborns with ELBW. For the analysis, loci with already known association with the development of type 2 diabetes mellitus were selected ‒ ADRB2 (rs1042713) and (rs1042714), ADRB3 (rs4994), GNB3 (rs5443), PPARA (rs4253778), PPARD (rs2016520), TCF7L2_IVS3 (rs7903146) and TCF7L2_IVS4 (rs12255372), PPARGC1A (rs8192678), MTHFR (rs1801131), PPARG (rs1801282), MTNR1B (rs10830963), SIRT1 (rs7069102).Results. In newborns with ELBW, we found a more frequent occurrence of the mutant allele A of the polymorphic locus rs8192678 in the PPARGC1A gene and the allele C of the polymorphic locus rs4253778 in the PPARA gene, in contrast to the adult population sample. But in newborns with ELBW, hyperglycemia is most likely associated with the carrier of the allele C rs1801282 of the PPARG gene (χ2 = 18.972, p < 0.001) and the allele T rs7903146 in the TCF7L2 gene (χ2 = 11.496, p < 0.001).Conclusions. The carriage of the allele С rs1801282 of the PPARG gene is characterized by the presence of a strong conjugation with hyperglycemia in newborns with extremely low body weight. It is desirable to monitor the level of glycemia in the conditions of neonatal intensive care units, taking into account the carriage of genes predisposing to hyperglycemia.
Clinical and economic assessment of the therapy of acute kidney injury in sepsis with continuous combined methods of renal replacement therapy
Authors: Polushin Y. . S , Dreval R. O. , Zabotina A. N. 
Published: November 2021

Objective: complex assessment of clinical and economic eﬀectiveness as well as saving of the state budget assets within the therapy of patients with sepsis/septic shock based on diﬀerent technologies of blood purification.Methods. Evaluation of direct and indirect costs of the eight blood purifcation methods. The target population includes adult patients 18+ with septic acute kidney injury. The study was conducted in compliance with acting Standards on Clinical Economic Studies used in the Russian Federation.The study methods included evaluation of existing randomized clinical studies and trials with data from network meta-analyses and systematic reviews of the target technologies. The direct medical and indirect non-medical costs were calculated and analyzed in respect of cost-eﬀectiveness and budget impact analyses.Results. Direct and indirect costs were calculated for the sorption devices oXiris (Baxter International Inc.), Toraymyxin (Toray Medical Co.), Alteco LPS Adsorber (Alteco Medical AB), Toxipak (POKARD NPF), Desepta.LPS (BIOTECH M NPP), CytoSorb (CytoSorbents Inc.), HA330 (Jafron Biomedical Co.), Desepta (BIOTECH M NPP) for two time-horizons: 1-year period and 5-years period with discounting. For both periods, the use of oXiris hemoflter results in the least economic burden for the state budget.Conclusion. The use of blood purifcation in septic patients therapy is associated with considerable direct and indirect fnancial expenses, the amount of which and consequential budget saving depend on the technology of blood purifcation applied. The actual tariﬀ compensation policy evidently demands revising.
Sepsis: source control
Authors: Kulabukhov V. V. , Zubareva N. A. , Yartsev P. A. 
Published: November 2021

Sepsis is a life-threatening condition, which is manifested by the development of organ dysfunction due to generalized inﬂammation caused by the infection of various nature. Timely lesion debridement combined with adequate antibiotic therapy are important components of the successful treatment of sepsis. At the moment, there is no consensus about the volume and time of intervention in the development of surgical sepsis. The article discusses modern approaches to solving the problem of adequate sanitation of the source of infection. The results of few randomized trials in this area are presented.Source control is absolutely essential for the successful treatment of sepsis. However, it is difcult to create a unifed algorithm for surgical control for all cases due to diﬀerent approaches depending on the infection location. Properly designed clinical trials are necessary to determine the optimal timing of surgery for sepsis and septic shock as least.