bluuebunny/crossref_metadata_2025_split huggingface dataset:
Renoprotective action of mucosa-adhesive phytogel "Biotrit" in rats, treated with oral application peroxide sunflower oil
Authors: Stepan V. T. 
Published: February 2021

Aim. Determine the renoprotective activity of oral “Biotrit” gel when exposed to peroxide sunflower oil (PSO).Methods. PSO was obtained by heating the oil at +180 ° C for 60 minutes in the presence of 1.5% H2O2. Used mucosa-adhesive phytogel "Biotrit", containing bioflavonoids from wheat leaves. Rats received oral applications of PSO at a dose of 0.5 ml/rat for 5 days. A part of the rats received 30 minutes before the application of the PSO application of the “Biotrit” gel. The activity of elastase, catalase, urease, lysozyme and the content of MDA were determined in the kidneys. The ratio of catalase and MDA was calculated the API index, and the ratio of the relative activities of urease and lysozyme – the degree of dysbiosis.Results. In rats treated with PSO, the activity of elastase, urease, and MDA content increased but lysozyme activity and the API index decreased in the kidneys. Applications of the gel "Biotrit" reduce the activity of elastase, urease, increase the activity of lysozyme and the API index.Conclusion. Consumption of PSO causes the development of nephropathy; Oral applications of the gel "Biotrit" prevent the development of peroxide nephropathy.
Correlation of body composition with depression level
Authors: Kusari Nertila , Sukova-Stojmanovska Daniela , Elezi Abdulla 
Published: February 2021

Background: The purpose of this paper is to determine the impact of body development and composition on the depression level, and to determine which of the morphological and body composition parameters have higher impact on the manifestation of depression in women aged 19 to 30 years.Methods: The study was conducted on the sample of 50 voluntarily selected test subjects. From 83 women presented at the fitness center “Fitnes Center Mall” in the city of Gjakova for the purposes of this study are voluntarily involved 50 women aged 19 to 30 years with an average age of 23.2 years. For the purpose of this paper were applied 11 body composition variables and one test for measuring depression levels.Results: The obtained results show that the multiple correlation coefficient between the predictor and the criterion system is quite high R = 0.962. This relation shows that the common variability between the two systems is 93% (R Square = 0.926). Predictive variables that has the influence in the manifestation of depression level are: Height of the body body (HEIG) t=2.784; p<0.008, Body weight (WEIG) t=-2.194; p<0.034, and Body mass index (BMI) t=2.908; p<0.006. Conclusions: The research results show that Height of the body, Body weight, and Body mass index affect in the rate of depression level. Research shows that although mental and physical health are two separate concepts, yet they are still in a strong relationship, physical condition affects in mental state.
Telemedicine in neurosurgery during SARS-CoV2 Pandemic
Authors: Golebiowska Maria , Golebiowska Beata 
Published: February 2021

Introduction and purposeFirst large scale introduction and research of telecommunication in medicine was conducted in year 1977. However, until current SARS-CoV-2 Pandemic, telemedicine has been used only in emergency interventions or in cases in which only remote healthcare provision services were available. Healthcare was forced to implement telemedical changes in a scale broader beyond imagination, in order to limit the risk of COVID transmission and preserve the scarce healthcare resources. Especially in surgical fields, such as neurosurgery, which strongly depend on on-site procedures, this time has been extremely demanding. The aim of the study is to present the current views and effectiveness of implementation of telemedicine in neurosurgery during SARS-CoV2 pandemic. Substantial articles on implementation and challenges of telemedicine in neurosurgery from period 02.2020-09.2020 were analyzed. Current state of knowledgeWithin 581 articles of PubMED database, 15 substantial articles on advancements of telemedicine in neurosurgery during SARS-CoV2 Pandemic were included in the review. 60% of the articles discussed telemedicine implementation and improvements made, 40% of the articles discussed the legislative changes, telemedicine recommendations and good pratices. Most of the articles noted the significant increase in provision of services using telemedicine and high satisfaction of patients and professionals from the remote visits. However, many challenges of the technology has been encountered including difficulties in conducting proper remote examination, lack of standarized protocols, concerns of the ethical and social matters, such as patient’s confidentiality and privacy concerns, digital illiteracy in patients, and the need for more advanced hardware and more secure software for the provision of high quality services. Conclusions Reviewed research presents significant improvements in introduction of telemedicine in neurosurgical field in times of COVID Pandemic, however due to many multidisciplinary concerns regarding telemedicine implementation, face-to-face examination and communication still should take priority over the telemedicine interventions in the non-emergency future.
Impact of coronavirus disease (Covid-19) within the third trimester of pregnancy
Authors: Boychuk A. V. , Khlibovska O. I. , Yakymchuk Y. B. 
Published: February 2021

Introduction. Assessment of pregnancy, fetal status, diagnosis of placental insufficiency (PI) in pregnant women with coronavirus COVID-19, is a topical issue in obstetric practice and is of great social value for the birth of healthy children.The aim of our study was to analyze the impact of coronavirus disease on pregnancy and fetal status.Methods and materials. An examination of 25 pregnant women who relapsed into Covid-2019, who were treated at Public Non-profit Enterprise Ternopil Municipal City Hospital No. 2. The control group consisted of 25 pregnant women with a physiological course of pregnancy, who gave birth to live full-term infants with mass-growth characteristics according to gestational age. The condition of the fetus was assessed according to ultrasound, cardiotocography. Criteria for inclusion in the study were laboratory confirmed by COVID-19 by polymerase chain reaction (PCR).Results and discussion. It was found that coronavirus disease was present in pregnant women 21 (84.0%) in mild form, 4 (16.0%) patients had pneumonia, but did not require hospitalization and did not require artificial ventilation, and were treated at home by a family doctor. The main complaints of patients were fever in 84.0% (21 pregnant women), cough - in 78.0% (19 pregnant women), myalgia - in 62.0% (15 pregnant women), headache - 84.0% (21 pregnant women) , sore throat - in 40.0% (10 pregnant women), general weakness in 70.0% (17 pregnant women). And 6 pregnant women (20%) of those surveyed had a mild asymptomatic course of the disease. The condition of the fetus was assessed by ultrasound and CTG of the fetus. Decrease in amplitude of oscillations less than 3 beats / min, absence of accelerations, emergence of decelerations, testify to the expressed signs of a hypoxia of a fruit and demand timely treatment and the decision of a question of urgent delivery.
Entrevista com Alessandra Izabel de Carvalho, Professora Associada da Universidade Estadual de Ponta Grossa e Editora da Revista de História Regional
Authors: Maleval Isadora Tavares , Atallah Cláudia , Cesco Susana 
Published: February 2021

Entrevista para a Revista Maracanan, n. 26 - "História Regional: novas perspectivas", jan.-abr. 2021.
Assessment of physical land suitability by GIS-based fuzzy AHP for rubber plantation at the Nam Dong district, Thua Thien Hue province
Authors: TRAN Thi Minh Chau , LE Dinh Huy , LE Ngoc Phuong Quy , NGUYEN Thi Hai , TRAN Trong Tan , TRINH Ngan Ha 
Published: February 2021

This research was conducted to determine the main influences and physical factors of land suitability for rubber plantation in the Nam Dong district, Thua Thien Hue province. Six factors such as soil type, soil texture, soil thickness, slope, soil pH and soil organic matter content were considered. Results indicate that soil thickness is has the highest role on the land suitability analysis while soil pH has the lowest. The physical land suitability of rubber plantation was divided into 4 levels: very suitable (10.1%), suitable (15.5%), slightly suitable (3.6%), and currently not suitable (70.8%). This research provides important information for rubber cultivation in projected agricultural land use planning of the Nam Dong district.
Nghiên cứu này được thực hiện nhằm xác định sự ảnh hưởng của các yếu tố tự nhiên đến sự thích nghi đất đai của loại hình sử dụng đất trồng cây cao su trên địa bàn huyện Nam Đông, tỉnh Thừa Thiên Huế. Có 6 yếu tố được xem xét trong nghiên cứu này bao gồm: loại đất, thành phần cơ giới, tầng dày canh tác, độ dốc, độ chua và hàm lượng mùn trong đất. Kết quả nghiên cứu chỉ ra rằng tầng dày canh tác là yếu tố có ảnh hưởng lớn nhất đến việc sử dụng đất trồng cây cao su, trong khi đó độ chua là yếu tố có ảnh hưởng ít nhất. Sự thích nghi tự nhiên của loại hình sử dụng đất trồng cây cao su được chia thành 4 mức độ bao gồm rất thích nghi (10,1%), thích nghi (15,5%), tương đối thích nghi (3,6%) và hiện taị không thích nghi (70,8%). Nghiên cứu này cung cấp những thông tin cần thiết và hữu ích cho việc quy hoạch sử dụng đất trồng cây cao su trên địa bàn huyện Nam Đông.
Goal Attainment Scaling: A Framework for Research and Practice in the Intellectual and Developmental Disabilities Field
Authors: Shogren Karrie A. , Dean Evan E. , Burke Kathryn M. , Raley Sheida K. , Taylor Julie Lounds 
Published: February 2021

Abstract
Goal setting and attainment is often a targeted outcome in the intellectual and developmental disabilities field; however, standardizing the measurement of attainment of individualized goals is challenging. The purpose of this article is to introduce a four-domain framework that provides a series of questions to research and evaluation teams in planning for the use of goal attainment scaling (GAS) as an outcome measure at the individual or aggregate level. We intend to stimulate discussion and ongoing work to further systematize how GAS is used in (a) intervention research to establish evidence-based practices and (b) practice to assess the extent to which interventions and supports lead to intended outcomes. The goal is to promote a clear planning process to inform data collection on individualized goal attainment outcomes that are rooted in goals and outcomes valued by people with intellectual and developmental disabilities.
A Pilot Study of a Future Planning Program for Siblings of People With Intellectual and Developmental Disabilities
Authors: Lee Chung E. , Burke Meghan M. 
Published: February 2021

AbstractGiven the increased longevity of people with intellectual and developmental disabilities (IDD), future planning programs are becoming increasingly common. However, although siblings are likely to fulfill caregiving roles for people with IDD, siblings have not been included in future planning interventions. The purpose of this study was to evaluate the outcomes and feasibility of the Sibling Training for Early future Planning (STEP) program. Using quantitative and qualitative data, 18 siblings of individuals with IDD participated in the study. After completing the STEP program, participants demonstrated significantly improved feelings of empowerment, disability connectedness, family communication, and knowledge of adult disability services. The STEP program was also feasible given high attendance, low attrition rates, and high participant satisfaction. Implications for research and practice are discussed.
Full optical SESAM characterization methods in the 1.9 to 3-µm wavelength regime
Authors: Heidrich Jonas , Gaulke Marco , Alaydin Behcet Ozgur , Golling Matthias , Barh Ajanta , Keller Ursula 
Published: February 2021

Semiconductor saturable absorber mirrors (SESAMs) are widely used for modelocking of various ultrafast lasers. The growing interest for SESAM-modelocked lasers in the short-wave infrared and mid-infrared regime requires precise characterization of SESAM parameters. Here, we present two SESAM characterization setups for a wavelength range of 1.9 to 3 µm to precisely measure both nonlinear reflectivity and time-resolved recovery dynamics. For the nonlinear reflectivity measurement, a high accuracy (<0.04%) over a wide fluence range (0.1–1500 µJ/cm2) is achieved. Time-resolved pump-probe measurements have a resolution of about 100 fs and a scan range of up to 680 ps. Using the two setups, we have fully characterized three different GaSb-SESAMs at an operation wavelength of 2.05 µm fabricated in the FIRST lab at ETH Zurich. The results show excellent performance suitable for modelocking diode-pumped solid-state and semiconductor disk lasers. We have measured saturation fluences of around 4 µJ/cm2, modulation depths varying from 1% to 2.4%, low non-saturable losses (∼ 0.2%) and sufficiently fast recovery times (< 32 ps). The predicted influence of Auger recombination in the GaSb material system is also investigated.
Constructing an achromatic polarization-dependent bifocal metalens with height-gradient metastructures
Authors: Xiong Xiang , Wang Xi , Wang Zhenghan , Gao Yajun , Peng Ruwen , Wang Mu 
Published: February 2021

Metalenses possess the extraordinary capability to tailor the wavefront of light with compact metastructures. However, it remains challenging to eliminate chromatic aberration and realize multifunctionality. Here we report an achromatic bifocal metalens (ABM) made of three-dimensional standing nano blocks (SNBs). By introducing a height gradient to SNBs, the ABM can achieve achromatic focusing in the wavelength range of 760–1550 nm with two different focal lengths by merely orthogonally switching the linear polarization of the incident beam. Such an achromatic multi-functional element may have applications in polarization sensing/display and shared-aperture optics design, among many others.
Compact long-range single-photon imager with dynamic imaging capability
Authors: Jiang Peng-Yu , Li Zheng-Ping , Xu Feihu 
Published: February 2021

Single-photon light detection and ranging (LiDAR) has emerged as a strong candidate technology for active imaging applications. Benefiting from the single-photon sensitivity in detection, long-range active imaging can be realized with a low-power laser and a small-aperture transceiver. However, existing kilometer-range active imagers are bulky and have a long data acquisition time. Here we present a compact co-axial single-photon LiDAR system for kilometer-range 3D imaging. A fiber-based transceiver with a 2.5 cm effective aperture was employed to realize a robust and compact architecture, while a tailored temporal filtering approach guaranteed the high signal-to-noise level. Moreover, a micro–electro–mechanical system scanning mirror was adopted to achieve fast beam scanning. In experiment, high-resolution 3D images of different targets up to 12.8 km were acquired to demonstrate the long-range imaging capability. Furthermore, it exhibits the ability to achieve dynamic imaging at five frames per second over a distance of

∼

1

k
m

. The results indicate potential in a variety of applications such as remote sensing and long-range target detection.
Sialotranscriptomics of the argasid tick Ornithodoros moubata along the trophogonic cycle
Authors: Oleaga Ana , Soriano Beatriz , Llorens Carlos , Pérez-Sánchez Ricardo 
Published: February 2021

The argasid tickOrnithodoros moubatais the main vector of human relapsing fever (HRF) and African swine fever (ASF) in Africa. Salivary proteins are part of the host-tick interface and play vital roles in the tick feeding process and the host infection by tick-borne pathogens; they represent interesting targets for immune interventions aimed at tick control.The present work describes the transcriptome profile of salivary glands ofO.moubataand assesses the gene expression dynamics along the trophogonic cycle using Illumina sequencing.De novotranscriptome assembling resulted in 71,194 transcript clusters and 41,011 annotated transcripts, which represent 57.6% of the annotation success. Most salivary gene expression takes place during the first 7 days after feeding (6,287 upregulated transcripts), while a minority of genes (203 upregulated transcripts) are differentially expressed between 7 and 14 days after feeding. The functional protein groups more abundantly overrepresented after blood feeding were lipocalins, proteases (especially metalloproteases), protease inhibitors including the Kunitz/BPTI-family, proteins with phospholipase A2 activity, acid tail proteins, basic tail proteins, vitellogenins, the 7DB family and proteins involved in tick immunity and defence. The complexity and functional redundancy observed in the sialotranscriptome ofO.moubataare comparable to those of the sialomes of other argasid and ixodid ticks.This transcriptome provides a valuable reference database for ongoing proteomics studies of the salivary glands and saliva ofO.moubataaimed at confirming and expanding previous data on theO.moubatasialoproteome.
Bone strain index as a predictor of further vertebral fracture in osteoporotic women: An artificial intelligence-based analysis
Authors: Ulivieri Fabio Massimo , Rinaudo Luca , Piodi Luca Petruccio , Messina Carmelo , Sconfienza Luca Maria , Sardanelli Francesco , Guglielmi Giuseppe , Grossi Enzo 
Published: February 2021

Background
Osteoporosis is an asymptomatic disease of high prevalence and incidence, leading to bone fractures burdened by high mortality and disability, mainly when several subsequent fractures occur. A fragility fracture predictive model, Artificial Intelligence-based, to identify dual X-ray absorptiometry (DXA) variables able to characterise those patients who are prone to further fractures called Bone Strain Index, was evaluated in this study.

Methods
In a prospective, longitudinal, multicentric study 172 female outpatients with at least one vertebral fracture at the first observation were enrolled. They performed a spine X-ray to calculate spine deformity index (SDI) and a lumbar and femoral DXA scan to assess bone mineral density (BMD) and bone strain index (BSI) at baseline and after a follow-up period of 3 years in average. At the end of the follow-up, 93 women developed a further vertebral fracture. The further vertebral fracture was considered as one unit increase of SDI. We assessed the predictive capacity of supervised Artificial Neural Networks (ANNs) to distinguish women who developed a further fracture from those without it, and to detect those variables providing the maximal amount of relevant information to discriminate the two groups. ANNs choose appropriate input data automatically (TWIST-system, Training With Input Selection and Testing). Moreover, we built a semantic connectivity map usingthe Auto Contractive Map to provide further insights about the convoluted connections between the osteoporotic variables under consideration and the two scenarios (further fracture vs no further fracture).

Results
TWIST system selected 5 out of 13 available variables: age, menopause age, BMI, FTot BMC, FTot BSI. With training testing procedure, ANNs reached predictive accuracy of 79.36%, with a sensitivity of 75% and a specificity of 83.72%.
The semantic connectivity map highlighted the role of BSI in predicting the risk of a further fracture.

Conclusions
Artificial Intelligence is a useful method to analyse a complex system like that regarding osteoporosis, able to identify patients prone to a further fragility fracture. BSI appears to be a useful DXA index in identifying those patients who are at risk of further vertebral fractures.
An economic analysis of the health-related benefits associated with bicycle infrastructure investment in three Canadian cities
Authors: Whitehurst David G. T. , DeVries Danielle N. , Fuller Daniel , Winters Meghan 
Published: February 2021

Objectives
Decision-makers are increasingly requesting economic analyses on transportation-related interventions, but health is often excluded as a determinant of value. We assess the health-related economic impact of bicycle infrastructure investments in three Canadian cities (Victoria, Kelowna and Halifax), comparing a baseline reference year (2016) with the future infrastructure build-out (2020).

Methods
The World Health Organization’s Health Economic Assessment Tool (HEAT; version 4.2) was used to quantify the economic value of health benefits associated with increased bicycling, using a 10-year time horizon. Outputs comprise premature deaths prevented, carbon emissions avoided, and a benefit:cost ratio. For 2016–2020, we derived cost estimates for bicycle infrastructure investments (including verification from city partners) and modelled three scenarios for changes in bicycling mode share: ‘no change’, ‘moderate change’ (a 2% increase), and ‘major change’ (a 5% increase). Further sensitivity analyses (32 per city) examined how robust the moderate scenario findings were to variation in parameter inputs.

Results
Planned bicycle infrastructure investments between 2016 and 2020 ranged from $28–69 million (CAD; in 2016 prices). The moderate scenario benefit:cost ratios were between 1.7:1 (Victoria) and 2.1:1 (Halifax), with the benefit estimate incorporating 9–18 premature deaths prevented and a reduction of 87–142 thousand tonnes of carbon over the 10-year time horizon. The major scenario benefit:cost ratios were between 3.9:1 (Victoria) and 4.9:1 (Halifax), with 19–43 premature deaths prevented and 209–349 thousand tonnes of carbon averted. Sensitivity analyses showed the ratio estimates to be sensitive to the time horizon, investment cost and value of a statistical life inputs.

Conclusion
Within the assessment framework permitted by HEAT, the dollar value of health-related benefits exceeded the cost of planned infrastructure investments in bicycling in the three study cities. Depending on the decision problem, complementary analyses may be required to address broader questions relevant to decision makers in the public sector.