bluuebunny/crossref_metadata_2025_split huggingface dataset:
User-Centered Development of a Web Platform Supporting Community-Based Health Care Organizations for Older Persons in Need of Support: Qualitative Focus Group Study
Authors: Biehl Verena , Becker Heidrun , Ogrin Alenka , Reissner Alenka , Burger Johannes , Glaessel Andrea 
Published: March 2021

Background
The ongoing changes in population demographics increase the relevance of dignified aging across Europe. Community-based health care (CBHC) organizations are necessary to provide sustainable strategies for organizing care for older persons in need of support. To support the digitalization of these organizations, new business models and suitable web platforms are necessary.

Objective
This study, which is part of the European Active and Assisted Living (AAL) project called “ICareCoops”, aimed to explore concepts, approaches, and workflows of CBHC organizations to achieve a comprehensive understanding of extant services offered and relevant requirements to support these services with information and computer technology (ICT) solutions.

Methods
A qualitative study with six focus groups (FGs) with 40 participants was conducted in Switzerland and Slovenia to identify potential stakeholders’ needs and requirements for the user-centered development of a web platform. Data were collected from three different stakeholder groups: (1) older persons in need of support as care receivers, (2) significant others of older persons in need of support, and (3) managers or care providers of CBHC organizations. A semistructured interview guide with open questions was used for data collection. FG sessions were audio-recorded and transcribed verbatim. Thematic content analysis was used to analyze the content of the FG sessions. To assist with further web platform development, the responses of the FG participants were translated into user stories to describe technical requirements.

Results
By analyzing the transcripts, five main categories were identified: (1) ICT usage behavior of users, (2) challenges of web platform usage, (3) content and technical requirements for the web platform, (4) form and services of CBHC organizations, and (5) rationales of CBHC organizations. The main issues identified were the need for seniors to have individual contact with the CBHC organization and the possibility to coordinate routine services via the web platform, such as ordering meals-on-wheels or booking a caregiver to accompany an older person to the doctor.

Conclusions
The majority of participants showed a lack of familiarity with the usage of ICT. Nevertheless, they were open-minded regarding web platform usage to facilitate workflows and to benefit CBHC organizations. Cooperatives as an organizational model demonstrate a high potential to address users’ needs. Therefore, the web platform offers an essential tool for innovative health care models in the future. Searching for care services, contacting care providers, and communicating with care providers was preferred via personal contact and seemed to be the key element for user acceptance and for the successful implementation of a web platform like “ICareCoops” to support CBHC organizations.
Using Machine Learning Imputed Outcomes to Assess Drug-Dependent Risk of Self-Harm in Patients with Bipolar Disorder: A Comparative Effectiveness Study
Authors: Nestsiarovich Anastasiya , Kumar Praveen , Lauve Nicolas Raymond , Hurwitz Nathaniel G , Mazurie Aurélien J , Cannon Daniel C , Zhu Yiliang , Nelson Stuart James , Crisanti Annette S , Kerner Berit , Tohen Mauricio , Perkins Douglas J , Lambert Christophe Gerard 
Published: March 2021

Background
Incomplete suicidality coding in administrative claims data is a known obstacle for observational studies. With most of the negative outcomes missing from the data, it is challenging to assess the evidence on treatment strategies for the prevention of self-harm in bipolar disorder (BD), including pharmacotherapy and psychotherapy. There are conflicting data from studies on the drug-dependent risk of self-harm, and there is major uncertainty regarding the preventive effect of monotherapy and drug combinations.

Objective
The aim of this study was to compare all commonly used BD pharmacotherapies, as well as psychotherapy for the risk of self-harm, in a large population of commercially insured individuals, using self-harm imputation to overcome the known limitations of this outcome being underrecorded within US electronic health care records.

Methods
The IBM MarketScan administrative claims database was used to compare self-harm risk in patients with BD following 65 drug regimens and drug-free periods. Probable but uncoded self-harm events were imputed via machine learning, with different probability thresholds examined in a sensitivity analysis. Comparators included lithium, mood-stabilizing anticonvulsants (MSAs), second-generation antipsychotics (SGAs), first-generation antipsychotics (FGAs), and five classes of antidepressants. Cox regression models with time-varying covariates were built for individual treatment regimens and for any pharmacotherapy with or without psychosocial interventions (“psychotherapy”).

Results
Among 529,359 patients, 1.66% (n=8813 events) had imputed and/or coded self-harm following the exposure of interest. A higher self-harm risk was observed during adolescence. After multiple testing adjustment (P≤.012), the following six regimens had higher risk of self-harm than lithium: tri/tetracyclic antidepressants + SGA, FGA + MSA, FGA, serotonin-norepinephrine reuptake inhibitor (SNRI) + SGA, lithium + MSA, and lithium + SGA (hazard ratios [HRs] 1.44-2.29), and the following nine had lower risk: lamotrigine, valproate, risperidone, aripiprazole, SNRI, selective serotonin reuptake inhibitor (SSRI), “no drug,” bupropion, and bupropion + SSRI (HRs 0.28-0.74). Psychotherapy alone (without medication) had a lower self-harm risk than no treatment (HR 0.56, 95% CI 0.52-0.60; P=8.76×10-58). The sensitivity analysis showed that the direction of drug-outcome associations did not change as a function of the self-harm probability threshold.

Conclusions
Our data support evidence on the effectiveness of antidepressants, MSAs, and psychotherapy for self-harm prevention in BD.

Trial Registration
ClinicalTrials.gov NCT02893371; https://clinicaltrials.gov/ct2/show/NCT02893371
Effectiveness of an Integrated Care Package for Refugee Mothers and Children: Protocol for a Cluster Randomized Controlled Trial
Authors: Al Azdi Zunayed , Islam Khaleda , Khan Muhammad Amir , Khan Nida , Ejaz Amna , Khan Muhammad Ahmar , Warraitch Azza , Jahan Ishrat , Huque Rumana 
Published: March 2021

Background
Thousands of Rohingya refugee mothers at the world’s largest refugee camp located in Bangladesh are at risk of poor mental health. Accordingly, their children are also vulnerable to delayed cognitive and physical development.

Objective
The aim of this study is to evaluate the effectiveness of an integrated care package in reducing the prevalence of developmental delays among children aged 1 year and improving their mothers’ mental health status.

Methods
This is a parallel, two-arm, single-blind, cluster randomized controlled trial (cRCT). A total of 704 mother-child dyads residing at the Kutupalong refugee camp in Cox’s Bazar, Bangladesh, will be recruited from 22 clusters with 32 mother-child dyads per cluster. In the intervention arm, an integrated early childhood development and maternal mental health package will be delivered every quarter to mothers of newborns by trained community health workers until the child is 1 year old. Our primary outcome is a reduction in the prevalence of two or more childhood developmental delays of infants aged 1 year compared to the usual treatment. The secondary outcomes include reduced stunting among children and the prevalence of maternal depression. We will also assess the cost-effectiveness of the integrated intervention, and will further explore the intervention’s acceptability and feasibility.

Results
At the time of submission, the study was at the stage of endpoint assessment. The data analysis started in December 2020, and the results are expected to be published after the first quarter of 2021.

Conclusions
This study will address the burden of childhood developmental delays and poor maternal mental health in a low-resource setting. If proven effective, the delivery of the intervention through community health workers will ensure the proposed intervention’s sustainability.

Trial Registration
ISRCTN Registry ISRCTN10892553; https://www.isrctn.com/ISRCTN10892553

International Registered Report Identifier (IRRID)
DERR1-10.2196/25047
Impact of the COVID-19 Pandemic on Older Adults: Rapid Review
Authors: Lebrasseur Audrey , Fortin-Bédard Noémie , Lettre Josiane , Raymond Emilie , Bussières Eve-Line , Lapierre Nolwenn , Faieta Julie , Vincent Claude , Duchesne Louise , Ouellet Marie-Christine , Gagnon Eric , Tourigny André , Lamontagne Marie-Ève , Routhier François 
Published: March 2021

Background
The COVID-19 pandemic has drastically changed the lives of countless members of the general population. Older adults are known to experience loneliness, age discrimination, and excessive worry. It is therefore reasonable to anticipate that they would experience greater negative outcomes related to the COVID-19 pandemic given their increased isolation and risk for complications than younger adults.

Objective
This study aims to synthesize the existing research on the impact of the COVID-19 pandemic, and associated isolation and protective measures, on older adults. The secondary objective is to investigate the impact of the COVID-19 pandemic, and associated isolation and protective measures, on older adults with Alzheimer disease and related dementias.

Methods
A rapid review of the published literature was conducted on October 6, 2020, through a search of 6 online databases to synthesize results from published original studies regarding the impact of the COVID-19 pandemic on older adults. The Human Development Model conceptual framework–Disability Creation Process was used to describe and understand interactions between personal factors, environmental factors, and life habits. Methods and results are reported following the Preferred Reporting Items for Systematic Reviews and Meta-analyses Statement.

Results
A total of 135 records were included from the initial search strategy of 13,452 individual studies. Of these, 113 (83.7%) studies were determined to be of level 4 according to the levels of evidence classification by the Centre for Evidence-Based Medicine. The presence of psychological symptoms, exacerbation of ageism, and physical deterioration of aged populations were reported in the included studies. Decreased social life and fewer in-person social interactions reported during the COVID-19 pandemic were occasionally associated with reduced quality of life and increased depression. Difficulties accessing services, sleep disturbances, and a reduction of physical activity were also noted.

Conclusions
Our results highlight the need for adequate isolation and protective measures. Older adults represent a heterogeneous group, which could explain the contradictory results found in the literature. Individual, organizational, and institutional strategies should be established to ensure that older adults are able to maintain social contacts, preserve family ties, and maintain the ability to give or receive help during the current pandemic. Future studies should focus on specific consequences and needs of more at-risk older adults to ensure their inclusion, both in public health recommendations and considerations made by policy makers.
Echo Chamber Effect in Rumor Rebuttal Discussions About COVID-19 in China: Social Media Content and Network Analysis Study
Authors: Wang Dandan , Qian Yuxing 
Published: March 2021

Background
The dissemination of rumor rebuttal content on social media is vital for rumor control and disease containment during public health crises. Previous research on the effectiveness of rumor rebuttal, to a certain extent, ignored or simplified the structure of dissemination networks and users’ cognition as well as decision-making and interaction behaviors.

Objective
This study aimed to roughly evaluate the effectiveness of rumor rebuttal; dig deeply into the attitude-based echo chamber effect on users’ responses to rumor rebuttal under multiple topics on Weibo, a Chinese social media platform, in the early stage of the COVID-19 epidemic; and evaluate the echo chamber’s impact on the information characteristics of user interaction content.

Methods
We used Sina Weibo’s application programming interface to crawl rumor rebuttal content related to COVID-19 from 10 AM on January 23, 2020, to midnight on April 8, 2020. Using content analysis, sentiment analysis, social network analysis, and statistical analysis, we first analyzed whether and to what extent there was an echo chamber effect on the shaping of individuals’ attitudes when retweeting or commenting on others’ tweets. Then, we tested the heterogeneity of attitude distribution within communities and the homophily of interactions between communities. Based on the results at user and community levels, we made comprehensive judgments. Finally, we examined users’ interaction content from three dimensions—sentiment expression, information seeking and sharing, and civility—to test the impact of the echo chamber effect.

Results
Our results indicated that the retweeting mechanism played an essential role in promoting polarization, and the commenting mechanism played a role in consensus building. Our results showed that there might not be a significant echo chamber effect on community interactions and verified that, compared to like-minded interactions, cross-cutting interactions contained significantly more negative sentiment, information seeking and sharing, and incivility. We found that online users’ information-seeking behavior was accompanied by incivility, and information-sharing behavior was accompanied by more negative sentiment, which was often accompanied by incivility.

Conclusions
Our findings revealed the existence and degree of an echo chamber effect from multiple dimensions, such as topic, interaction mechanism, and interaction level, and its impact on interaction content. Based on these findings, we provide several suggestions for preventing or alleviating group polarization to achieve better rumor rebuttal.
THE YORÙBÁ’S PEACEFULNESS ENHANCED BY AN INFORMAL PEACE EDUCATION
Authors: Olayinka Akintayo Sunday 
Published: March 2021

This paper is a review of the southwest Nigerian Yorùbá and their
recognized peacefulness in the context of Nigeria as a country. It
attempts to address the peacefulness amidst the Nigeria unstable
circumstances and in comparison, with the established peaceful societies
(PS). The first part of the paper provides a concise discussion about
peace and conflict studies as it developed in the West followed by an
outline of conflicts in Nigeria and amongst the Yorùbá to identify a gap
for this inquiry. The paper suggests the Yorùbá multireligious community
provides some clues to how peacefulness could be retained in a society.
Similarly, it suggests the roles informal peace education play in
supporting people of different beliefs but same culture to retain their
harmony. The author, nevertheless, left a challenge to move the study of
PS beyond the agrarian and rural communities to investigate more modern
societies for peacefulness.
NOTE: This article is taken from part of chapter 2 and the
conclusion of the author’s doctoral thesis, with a few amendments.
NUMERICAL COMPARISON OF RUNGE-KUTTA (RK5) AND NEW ITERATIVE METHOD (NIM) FOR SOLVING METASTATIC CANCER MODEL
Authors: Iyanda Falade Kazeem , Tunde Tiamiyu Abd`Gafar , Isa Umar 
Published: March 2021

This paper attempts to present and employ Runge-Kutta Method of fifth-order (RK5) and New Iterative Method for the numerical solution of metastatic cancer model which occur in two compartments of cancer environment. These methods have been proved to be powerful mathematical tools for various phenomena in biomathematics and it is extremely effective for linear and non-linear systems of differential equations. Our numerical experiments illustrate the effect of parameters on cancer models which are responsible for the spread or reduction of cancer cells through the boundary of an organ tissue. The results obtained are compared with analytical solutions and show that (RK5) and NIM are powerful numerical techniques to solve systems of differential equations. Finally, all computations and algorithms are implemented using MAPLE 18 software version.
Activismo e investigación: recuperando el concepto de neutralidad valorativa en la formación de tipos ideales
Authors: Cáñez Cota Antonio 
Published: March 2021

El presente artí­culo discute la propuesta metodológica weberiana de tipo ideal como una manera de encontrar neutralidad-libertad valorativa en la investigación social contemporánea, la cual exige un mayor involucramiento de los investigadores con los problemas prácticos que ocurren a su alrededor. En la actualidad, el individualismo metodológico es una de las metodologí­as más utilizadas, su fundación se sostiene en las aportaciones de Max Weber, que se pueden resumir en tres: la primera se refiere a la transparencia de la cuestión valorativa del investigador; la segunda es la construcción de una acción racional de tipo ideal como instrumento de interpretación con alta disciplina cientí­fica; por último, se muestra el manejo de la información empí­rica para imputar una relación causal apropiada para el contexto histórico que se analiza. La principal aportación del artí­culo es que muestra cada una de las fases del método de elaboración de tipos ideales, con el fin de ofrecer una alternativa para el tránsito entre la investigación y el activismo: separar y explicitar los valores teóricos-conceptuales de los prácticos-emocionales.
El estudio de la puesta en acto de las polí­ticas educativas en clave microfí­sica
Authors: Villagran Carla Andrea 
Published: March 2021

En este artí­culo desarrollamos algunas problematizaciones y reflexiones en torno a la construcción metodológica y conceptual para el estudio de la puesta en acto (Ball, Maguire & Braun, 2012) de polí­ticas educativas a nivel de las instituciones escolares. Proponemos un abordaje etnográfico (Rockwell, 1987, 1995) y una analí­tica microfí­sica (Deleuze, 2014) de los procesos de puesta en acto, centrados en la descripción de los efectos y modos de afectación que producen las polí­ticas una vez que llegan a las escuelas. Partimos de la premisa de que no estudiamos las escuelas sino “en” escuelas y atendiendo a los saberes y experiencias de los sujetos.
AUTOMATSKO GENERISANJE SKUPA PODATAKA ZA TRENIRANJE MODELA ZA AUTOMATSKO PREPOZNAVANJE OSOBE NA SLICI
Authors: Sabadoš Noemi 
Published: March 2021

Kvalitetni skupovi podataka su retko dostupni, što otežava treniranje kvalitetnih modela mašinskog učenja. Cilj ovog rada je generisanje skupa podataka koji bi mogao biti korišćen za obuku modela mašinskog učenja čiji bi cilj bio da uporedi slike ljudi sa slikama poznatih ličnosti i prepozna sličnosti u izgledu. Generisanje skupa podataka se vrši automatski, na osnovu unapred zadatih kriterijuma. Svrha kriterijuma je da učine skup podataka raznovrsnim, sa ciljem poboljšanja generalizacije nad njime obučenih modela. Podržani kriterijumi uključivanja slika u skup podataka su sledeći: (1) da li se osoba smeši ili ne, (2) specifikacija smera pogleda, (3) činjenica da li osoba ima: bradu, šiške, kosu, (4) da li osoba nosi naočare ili kapu i (5) da li osoba rukom zaklanja lice. Prikupljeni skup podataka sadrži slike o 100 glumca, koje su skinute sa interneta prema zadatim kriterijumima.
MITOS KECANTIKAN PEREMPUAN EKSTRA MELALUI IKLAN NIVEA “EXTRA CARE FOR EXTRA WOMEN”
Authors: Christina Christina , Vallerie Natasha Richie , Marta Rustono Farady 
Published: March 2021

Abstract Beautiful woman standards cannot be separated from the media construction of the meaning of beauty. The media displays the standard of beauty that is consumed every day by the people of Indonesia through content and also advertising. An advertisement cannot be separated from a visual character that is built in such a way that it can be an inspiration or can represent the product or service advertised, not only that the visual character in the ad also shows other aspects such as social values and norms, images and lifestyle. This aspects standard certainly affects the views of Indonesian women on beauty. Nivea realizes that every woman is beautiful and has their own potential, so Nivea creates an Nivea extra care for extra women ad. This study aims to determine the myth of extra female beauty from the Nivea Extra Care for Extra Women ad. His research methods are qualitative, Roland Barthes's semiotics and Oswald's semiotic marketing, related to beauty myths. The object is the Nivea Extra Care for Extra Women ad on Youtube. Keywords: Beauty Mthy, Semiotic Marketing, Barthes, Advertisement Abstrak Standar wanita cantik tidak lepas dari konstruksi media tentang makna kecantikan. Media menampilkan standar kecantikan yang dikonsumsi setiap hari oleh masyarakat Indonesia melalui konten dan juga iklan. Iklan tidak lepas dari karakter visual yang dibangun sedemikian rupa sehingga dapat menjadi inspirasi atau dapat merepresentasikan produk atau jasa yang diiklankan, selain itu karakter visual pada iklan tersebut juga menunjukkan aspek lain seperti nilai dan norma sosial, gambar dan gaya hidup. Hal-hal ini tentunya mempengaruhi pandangan wanita Indonesia tentang kecantikan. Nivea menyadari bahwa setiap wanita itu cantik dan memiliki potensi masing-masing, sehingga Nivea membuat iklan Nivea extra care untuk wanita ekstra. Penelitian ini bertujuan untuk mengetahui mitos kecantikan wanita ekstra dari iklan Nivea Extra Care for Extra Women. Metode penelitiannya kualitatif, semiotika Roland Barthes dan pemasaran semiotik Oswald, terkait mitos kecantikan. Objeknya adalah iklan Nivea Extra Care for Extra Women di Youtube. Kata kunci: Mitos Kecantikan, Pemasaran Semiotik, Barthes, Iklan