bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Opioids and Psychoactive Drugs on Blood Lipid and Glucose Indices;
A Systematic Review of Population-Based Evidences
Authors: Rezaei Azam , Rezaei Maryam 
Published: August 2021

Background:
Based on a common belief among people, narcotic substances and psychoactive
drugs may help to reduce blood glucose and lipid profile leading to reduced risk of cardiovascular
diseases. This hypothesis has been verified in several studies; however, there is no conclusive
agreement on the reducing effects of opium and other opioid derivatives on blood glucose
and lipids. In the present review, we collected all related literature to evaluate the effects of opioids
and psychoactive drugs abuse in altering blood glucose and lipid profile, and discuss their longterm
effects.

Methods:
A systematic literature search was performed in January 2021 using “lipid profile”, “glucose”,
and “opium” including all their equivalents, main derivatives and similar terms. The data
were then extracted and reported qualitatively.

Results:
Overall, 46 articles with 37407 participants were included after several step–by-step procedures
of article selection. Findings of this study suggested that opioids may reduce blood glucose
and low-density lipoproteins, while increasing triglyceride. However, these effects are temporary,
and long-term substance abuse exacerbates glucose and lipid-associated diseases such as diabetes
and atherosclerosis.

Conclusion:
Although there are many confounding factors that may affect the results of the included
literature; however, based on the findings of these studies, the long-term beneficial effects of
opioids on lipid profile and blood glucose cannot be accepted.
Dynamics and Interplay between Autophagy and Ubiquitin-proteasome system Coordination in Skeletal Muscle Atrophy
Authors: Singh Ajay , Yadav Aarti , Phogat Jatin , Dabur Rajesh 
Published: August 2021

Abstract:Skeletal muscles are considered the largest reservoirs of the protein pool in the body and are critical for the maintenances of body homeostasis. Skeletal muscle atrophy is supported by various physiopathological conditions that lead to loss of muscle mass and contractile capacity of the skeletal muscle. Lysosomal mediated autophagy and ubiquitin-proteasomal system (UPS) concede the major intracellular systems of muscle protein degradation that result in the loss of mass and strength. Both systems recognize ubiquitination as a signal of degradation through different mechanisms, a sign of dynamic interplay between systems. Hence, growing shreds of evidence suggest the interdependency of autophagy and UPS in the progression of skeletal muscle atrophy under various pathological conditions. Therefore, understanding the molecular dynamics and associated factors responsible for their interdependency is necessary for the new therapeutic insights to counteract muscle loss. Based on current literature, the present review summarizes the factors that interplay between autophagy and UPS in favor of enhanced proteolysis of skeletal muscle and how they affect the anabolic signaling pathways under various conditions of skeletal muscle atrophy.
COMPOSITE RESIN RESTORATION WITH FIBER REINFORCED COMPOSITE AFTER ROOT CANAL TREATMENT OF NECROTIC PULP TOOTH WITH GUMBOIL
Authors: Natalia Dessy , Kristanti Yulita 
Published: August 2021

Gumboil is inflammation reaction in the gum caused by pulp infection. Gumboil is seen as an oral lesion characterized by a soft erythematous papule where a periapical abcess is draining into the oral cavity. An adequate root canal treatment can cure gumboil and remove bacteria from the root canal. To support the success of root canal treatment, final restoration used in this case is composite resin restoration with reinforcing fiber (short fiber reinforced composite). The purpose of this treatment was to restore the functions of tooth in mastication and preserving the supporting tissue. A female patient age 23 years old came with complaints of pain in the lower right mandibular molar accompanied by swelling of the gums around the teeth since a week ago. Swelling is intermittent since last 3 months. The tooth have been restored for about 3 years ago. Clinical examination showed a positive percussion, positive palpation, negative vitality, and negative mobility. Radiographic examination showed bifurcation and periapical lesions. Root canal treatment is performed with crown down preparation technique and followed by direct composite resin restoration with short fiber reiforced composite. The success of root canal treatment followed by composite resin restoration with short fiber reinforced fiber is marked by the absence of complaints as well as the dissappearance of gumboil.
Actitudes hacia la pandemia y su relación con la resiliencia en estudiantes de medicina peruanos
Authors: Garayar-Peceros Humberto , Prado-Martínez Fanny , Cortez-Soto Andrea G. , Niño de Guzmán Solange , García-Gutiérrez Julia G. , Alarco J. Jhonnel 
Published: August 2021

Introducción: Los estudiantes de medicina son uno de los grupos poblacionales más afectados por la COVID-19. Objetivo: Determinar las actitudes hacia la pandemia por la COVID-19 y su relación con la resiliencia en estudiantes de medicina a inicios de la cuarentena en Perú.
Método: Se realizó un estudio transversal analítico en estudiantes de medicina de dos universidades de la ciudad de Ica en Perú. Las preguntas referidas a las actitudes hacia la pandemia fueron elaboradas por los autores y la resiliencia fue medida a través de la versión en español de la escala de resiliencia de Connor-Davidson (CD-RISC-10).
Resultados: Se incluyeron 431 encuestas virtuales correctamente llenadas. Los estudiantes con actitudes positivas hacia la pandemia tuvieron puntajes más elevados de resiliencia (p < 0.05). La mediana global de resiliencia fue de 31 (RIC: 27-35) y la correlación entre el puntaje total de las actitudes positivas y el puntaje total de la resiliencia fue positiva, baja, pero altamente significativa (Rho de Spearman = 0.34, p < 0.001).
Conclusiones: A inicios de la cuarentena por la COVID-19 en Perú, los estudiantes de medicina de la ciudad de Ica tenían actitudes positivas hacia la evolución de la pandemia. Estas actitudes positivas se correlacionaron significativamente con los niveles de resiliencia.
Mapeamento dos cursos de Pedagogia e do estado da arte sobre indicadores da Arte na Pedagogia
Authors: Nunes Ana Luiza Ruschel , Bulaty Andréia 
Published: August 2021

O objetivo do texto é mapear, descrever e sistematizar as pesquisas brasileiras que têm como foco de estudo a Arte na Pedagogia, pesquisando e mapeando os cursos de licenciatura em Pedagogia no Brasil e do estado da arte e do conhecimento das produções acadêmicas sobre a arte na Pedagogia, no período de 2006 a 2018, com a problemática investigada: Qual é o estado da arte e do conhecimento das produções da pesquisa acadêmicas sobre e da Arte na Pedagogia? A pesquisa é qualitativa delineada pela metodologia do Estado da Arte e do Conhecimento em que foi encontrado 43 produções científicas no período de 12 anos. O Brasil em 2018, tinha 2752 cursos de Pedagogia, destes 1333 cursos presenciais e 1389 EaD, sendo que no Paraná tem 183 cursos Pedagogia.
Post-Space Treatment Influences the Bond Strength In Endodontically Treated Teeth: A Systematic Review and Meta-Analysis of In Vitro Studies
Authors: Bohrer TC , Fontana PE , Rocha RO , Kaizer OB 
Published: August 2021

SUMMARY

Objectives:
This systematic review of in vitro studies investigated the influence of the post-space treatment used to remove the smear layer on the bond strength of the post to root canal dentin.

Methods and Materials:
In vitro studies included in this study were identified from PubMed/MEDLINE, Lilacs, and Scopus databases up until March 2019, without limits on publication year or language. Two reviewers independently selected the studies based on the inclusion and exclusion criteria, extracted the data, and evaluated the risk of bias of all studies. A random effects model was used for pairwise meta-analyses (control vs. post-space preparation groups) at a significance level of p&lt;0.05.

Results:
Of the 2,832 potentially eligible studies, 453 studies were selected for full-text analysis, and 75 were included in this systematic review. Only one study was considered to have a low risk of bias. Overall, post-space treatment significantly improves the bond strength to root canal dentin (p&lt;0.00001).

Conclusion:
Post-space treatment has a positive influence on the bond strength of the post to root canal dentin. In this review, the post-space treatments that improve the adhesive resistance of the post were ethanol, sodium hypochlorite, and ethylene diamine tetra-acetic acid (NaOCl + EDTA), NaOCl + EDTA + ultrasound, erbium-doped yttrium aluminium garnet laser (Er:YAG laser), neodymium-doped yttrium aluminium garnet laser (Nd:YAG laser), and diode laser.
ABOUT EXPLOSION FUNNEL OF THE GLACIER KOLKA
Authors: Бергер М.Г. 
Published: August 2021

Показано существование воронки выброса на месте ледника Колка. Охарактеризованы основные особенности строения и морфологии этой воронки и дано их объяснение.
The existence of an explosion funnel on the glacier Kolka place was shown. The main features of structure and morphology of this funnel were given and explained
DEVELOPMENT OF ENGINEERING GEOLOGICAL ZONING MAPS OF THE REPUBLIC OF NORTH OSSETIA-ALANIA SETT LEMENTS, AS THE BASIS OF SEISMIC MICROZONATION
Authors: Джгамадзе А.К. , Заалишвили В.Б. , Гогичев Р.Р. 
Published: August 2021

В результате проведения исследований созданы карты инженерно-геологического районирования территорий гг. Владикавказ, Беслан, Ардон, Алагир и Дигора. Материалы исследований, составляющие инженерно-геологическую основу карт сейсмического микрорайонирования, представлены в виде набора карт, выполненных в форме ГИС проекта, и содержат информацию, необходимую и достаточную для вы- деления однородных в инженерно-сейсмогеологическом отношении территориальных единиц
The zoning of cities Vladikavkaz, Beslan, Ardon, Alagir and Digora is completed. The results of research that are engineering-geological base of seismic microzonation maps are given as a set of maps in GIS project form, and contain the information necessary and sufficient for allocation of territorial units homogenous in engineer and seismo-geological respect.
SEISMIC HAZARD OF GANJA CITY
Authors: Аллахвердиева З.Г. 
Published: August 2021

Изучение сейсмического риска города Гянджа на наш взгляд имеет большое значение, так как этот город является вторым промышленным центром республики. Для имеющихся очагов сильных землетря- сений в районе г. Гянджи на основе магнитуды вероятного максимально сильного землетрясения по эмпирической формуле М. В. Шебалина для разных глубин и расстояний был вычислен сейсмический эффект. Результаты показывают, что очаги, расположенные на районе Гек-гель и Зурнабад с сейсмической точки зрения наиболее опасные. Вероятность создания опасного сейсмического эффекта от Дашкесанских, Ге- дебекских и Келбаджарских очагов мала
Investigation of seismic risk of Ganja city in our opinion is of a great importance, since this city is the second industrial center of the country. The seismic effect was calculated for existing sources of strong earthquakes in the area of Ganja city -based on the magnitude of probable maximum strong earthquake using the empirical formula of M. V. Shebalin for various depths and distances. The results show that focal points located in the areas Gek-gel and Zurnabad are most hazardous from seismic point of view. Probability of hazardous seismic effect occurrence from Dashkesan, Gedebeksk, Kelbadzhar focal points is small
ANALYSIS OF THE CONCEPTS OF SEISMIC ACTIONS ON THE CIVIL CONSTRUCTIONS
Authors: Чотчаев Х.О. 
Published: August 2021

При этом используется целый ряд современных принципов и подходов. Здесь, в частности, активно развивается вероятностный подход, приближающий оценку сейсмической ситуации к реальной. В то же время почти каждое разрушительное землетрясение высвечивает ряд все новых проблем или в очередной раз демонстрирует ограниченность наших знаний. В статье приводится анализ некоторых концепций сейсмических воздействий на инженерные сооружения. Любая территория в сейсмически опасном регионе подлежит специальному изучению на предмет дифференциации зон с различной сейсмической опасностью
In this case a whole series of contemporary principles and approaches is used. Here, in particular, actively is developed the probabilistic approach, which brings the estimation of seismic situation closer to real. At the same time almost each destructive earthquake luminesces a number of new problems or demonstrates again and again the limitedness of our knowledge. In the article the analysis of some concepts of seismic actions on the civil constructions is given. Any territory in the seismically dangerous region is a subject to special study to the object of the differentiation of zones with different seismic danger.
SOME PROBLEMS OF THE SEISMIC MICROZONATION PRACTICAL REALIZATION. FACTORS, WHICH FORM THE INTENSITY OF THE EARTHQUAKE
Authors: Заалишвили В.Б. 
Published: August 2021

Установлены взаимосвязи амплитуд ускорений и спектров колебаний, особенности которых связаны с нелинейно-упругими и неупругими явлениями в грунтах при сильных воздействиях. Проведен анализ целого ряда факторов определяющих уровень сейсмической интенсивности. Показано, что созданы ус- ловия для составления карты сейсмического микрорайонирования не в традиционных единицах интен- сивностей, а непосредственно в единицах ускорений. Расчетный и инструментально-расчетный методы сейсмического микрорайонирования уже дают возможность представлять результаты в виде ускорений. Следовательно, в дополнение к традиционно используемым приращениям интенсивности, необходимо получать результаты основного инструментального метода сейсмического микрорайонирования также в виде ускорений. Предложены универсальные показатели, которые можно использовать для учета ускоре- ний в неявном виде, которые отличаются простотой получения и характеризуются большой общностью. Показана необходимость дальнейшего уточнения полученных показателей с целью стандартизации кри- териев.
The interrelations of the amplitudes of accelerations and oscillation spectra are established, whose special features are connected with the nonlinearly elastic and inelastic phenomena in the soils under the strong impact. The analysis of a whole series of the factors determining the level of seismic intensity is carried out. It is shown that the conditions for mapping of seismic zoning are created not in the traditional units of intensities, but directly in the accelerations unit. The calculated and instrumental-calculated methods of seismic zoning give the possibility to present the results in the form of accelerations. Consequently, in addition to the traditionally used intensity increments, it is necessary to obtain the results of the basic instrument method of seismic zoning also in the kind of accelerations. The universal indices are proposed, which can be used to account the accelerations implicitly, which are characterized by simplicity of obtaining and by large generality. The need for further refinement of the obtained indices for the purpose of the standardization of criteria is shown
ON THE SEISMIC HAZARD IN THE AZERBAIJAN TERRITORY
Authors: Маммадли Т.Я. 
Published: August 2021

Анализируются предыдущие и ныне действующие карты сейсмического районирования территории Азербайджана, методы их составления. Отмечается неадекватность этих карт на реальную сейсмическую опасность. Предлагается новый метод оценки сейсмической опасности. Выявлена высокая дифференциация сейсмической сотрясаемости территории Азербайджана в пространстве и по степени ее проявления.
The previous and now acting maps of the seismic zoning of the Azerbaijan territory, the methods of their composition are analyzed. The inadequacy of these maps to the real seismic danger is noted. The new method of evaluating the seismic danger is proposed. The high degree of the seismic shakability differentiation of the Azerbaijan territory in the space and according to the degree of its manifestation is revealed.
DEPENDENCE OF THE SPECTRAL CHARACTERISTICS OF SEISMIC WAVES ON THE STRUCTURE OF THE UPPER PART OF THE SECTION
Authors: Заалишвили В.Б. 
Published: August 2021

В работе рассмотрены вопросы зависимости спектральных характеристик сейсмических волн от строения верхней части разреза. Показано, что введение величины средневзвешенного периода коле- баний грунтов значительно повышает качество дифференциации грунтов различного вида. Приведены результаты анализа полевых данных в виде соотношений для расчетов плотностей грунтов различных видов. Рассмотрена зависимость спектрального состава сейсмических волн от мощности, физико-меха- нических свойств грунтов, слагающих грунтовую толщу, и гидрогеологических условий. На основе анализа данных сделан вывод о высокой целесообразности использования при сейсмиче- ском микрорайонировании мощных импульсных и вибрационных искусственных невзрывных источников. В работе использовались комплекс методов: полевые и численные (на физико-математических моделях) эксперименты, а также проведение экспериментов по анализу спектральных характеристик грунтов на лабораторных моделях. Особое внимание было уделено исследованию показателей поглощения сейсмической энергии в раз- личных видах грунтов. Показано, что использование расширенного типа показателей грунтов, в частности, за счет включения стандартных спектральных характеристик позволяет значительно повысить достоверность и надежность установления инженерно-геологического разреза грунтовой толщи и ее гидрогеоло- гических условий.
In the article were examine the dependence of the spectral characteristics of seismic waves on the structure of the upper part of the section. It is shown that the introduction of the value of the weighted mean period of oscillations of soils considerably increases the quality of the differentiation of the soils of different form. The results of the analysis of field data in the form of relationships for the calculations of terrain densities of different forms are given. The dependence of the spectral composition of seismic waves on the power, the physicomechanical conditions of the ground, component ground thickness, and hydrogeological conditions is examined. The conclusion about the high expediency of use with seismic city planning of powerful pulse and vibration artificial nonexplosive sources is made on the basis of data analysis. In the work there were used the complex of the methods: field and numerical (on the physico-mathematical models) experiments, and also conducting experiments according to the analysis of the spectral characteristics of soils on the laboratory models Special attention was given to a study of the absorption coefficients of seismic energy in different forms of soils. It is shown that use of the extended type of the indices of soils, in particular, due to the start of standard spectral characteristics makes it possible to considerably increase authenticity and reliability of the establishment of the geological engineering section of ground thickness and its hydrogeological conditions
DATABASE OF SEISMIC OBSERVATION NETWORK «VLADIKAVKAZ»
Authors: Заалишвили В.Б. , Мельков Д.А. , Кануков А.С. 
Published: August 2021

В связи с необходимостью изучения и последующего анализа малоизученного проявления особен- ностей воздействия активных разломов на ситуацию в городе и с целью изучения влияния различных типов грунтов и их физического состояния на сейсмический эффект на территории г. Владикавказа в августе 2004 г. создана локальная сеть сейсмологических наблюдений. Широкий спектр решаемых за- дач определяет особенности работы сети и соответствующей базы данных Создан набор программ для организации сбора, хранения и доступа к данным инженерных сейсмологических наблюдений на основе отечественных регистраторов Дельта-Геон .
In connection with the necessity of study and the following analysis of insufficiently researched occurrence of influence features of active faults on situation in the city and with the purpose to study influence of different soil types and their physical conditions on seismic effect local seismic observation network was created on the territory of Vladikavkaz city in August 2004. Wide spectrum of solving problems determines the features of network functioning and the corresponding database. Program set for data collection operation, storage and access to the data of engineering seismological observations was created on the basis of domestic recorders Delta-Geon .
GEO-ECOLOGICAL ANALYSIS OF THE COMPLEX GEOCHEMICAL POLYMETALLIC DZHIMIDON LAYER STUDIES RESULTS
Authors: Заалишвили В.Б. , Тигиева З.В. 
Published: August 2021

Техногенное воздействие человека на литосферу приводит к крупномасштабным изменениям в при- родной среде, активизирует развитие в ней ряда опасных процессов и служит причиной появления новых природно-техногенных явлений. В процессе поисков полезных ископаемых с целью заверки геофизических аномалий и уточнения их природы на Джимидонском участке была проведена литогеохимическая съемка по профилям. По результатам обработки геохимических данных было выделено 5 мультипликативных ореолов (аномалий). Сопоставление всех количественных геохимических и геофизических характеристик, позволяет сделать вывод, что некоторые геохимические аномалии, выявленные на Джимидонском месторождении, скорее всего, техногенного происхождения, образованные при транспортировке руды в результате ее потери и складирования, а также при разработке разведочных выработок
The technogenic action of man on the lithosphere leads to the large-scale changes in the natural medium, activates the development in it a number of dangerous processes and serves as a reason of the new naturaltechnogenic phenomena appearance. In the process of the mineral searches for the purpose of geophysical anomalies verification and refinement of their nature in the Dzhimidon site was the lithogeochemical survey along the profiles carried out. According to the results of geochemical data processing were isolated 5 multiplicative halos (anomalies). The comparison of all quantitative geochemical and geophysical characteristics, makes it possible to draw the conclusion that some geochemical anomalies, revealed on the Dzhimidon layer, most likely, has the technogenic origin, formed with the transport of the ore as a result of its loss and storing, and also with the development of prospectings