bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS SENTIMEN KELUHAN PENGGUNA PADA GAME SUPREMACY 1914 MENGGUNAKAN ALGORITMA K-MEANS CLUSTERING
Authors: Cevin Jery , Gultom David , Orlando Nikolas , Hendrik Fery Herdiatmoko  
Published: January 2025

Penelitian ini bertujuan menganalisis keluhan pengguna untuk pengembangan game Supremacy 1914 dengan memanfaatkan 1000 ulasan berbahasa Indonesia di Google Playstore. Ulasan ini diproses melalui tahapan preprocessing, seperti pemisahan kata (tokenizing), penyaringan (filtering), penghapusan kata tidak penting (stop word), dan pengubahan kata ke bentuk dasar (stemming). Data yang telah diproses dikelompokkan menggunakan metode K-Means menjadi tiga kelompok (cluster), yang divisualisasikan dalam bentuk wordcloud. Cluster 0 mencakup ulasan umum dengan kata-kata seperti "bagus", "seru", dan "mantap", sedangkan Cluster 1 fokus pada masukan terkait kualitas game dan pengalaman pengguna. Penelitian ini diharapkan membantu pengembang mengidentifikasi kebutuhan pengguna lebih cepat, meningkatkan kepuasan, dan mendukung pengembangan game secara berkelanjutan.
Investigation of the effect of acute exercise on oxidative stress and thiol-disulfide homeostasis in soccer players
Authors: Aktas Yakup , Celik Hakim , Daglı Seyda Nur , Erel Ozcan , Neselioglu Salim 
Published: January 2025

The aim of this study was to investigate the effects of acute exercise on oxidative stress and thiol-disulfide homeostasis in male soccer players. Thirty-two male soccer players from Şanlıurfa 11 Nisan Sports Club, a Turkish Football Federation Regional Amateur League (RAL) team, with a mean age of 21.36±0.56 years, a mean body weight of 70.58±1.60 kg, a mean height of 178.31±1.62 cm, and a mean body mass index (BMI) of 22.16±0.26 kg/m², with a sports history of at least 7 years, who regularly train 2 hours a day, 5 days a week, participated voluntarily in the study. After a 15-minute warm-up exercise, the Conconi Test was performed until fatigue was reached. Pre- and post-exercise oxidative stress levels and thiol-disulfide homeostasis (TDH) parameters were analyzed by an automated spectrophotometric method. SPSS 26 (Statistical package for social sciences) package program was used in the statistical analysis of the data. “Paired sample t test” was used to determine the differences between the pre-test and post-test. The significance between the differences was determined at P<0.05 level. Although an increase in oxidative stress levels was observed after exercise, this increase was not statistically significant (p>0.05). When thiol-disulfide homeostasis before and after exercise was compared, it was found that post-exercise values were significantly higher (p<0.05). This study, it is noteworthy that the negative effects of acute exercise on oxidative stress were not observed in soccer players in the literature. This may be explained by the strengthening of the antioxidant defense mechanisms of the participating soccer players due to their long-term sports history and the related positive adaptations. It is thought that regular and long-term exercise is effective in maintaining thiol-disulfide balance by strengthening the body’s antioxidant defense system, thus reducing the negative effects of oxidative stress and minimizing disease risks.
SLFCNet: an ultra-lightweight and efficient strawberry feature classification network
Authors: Xu Wenchao , Wang Yangxu , Yang Jiahao 
Published: January 2025

Background
As modern agricultural technology advances, the automated detection, classification, and harvesting of strawberries have become an inevitable trend. Among these tasks, the classification of strawberries stands as a pivotal juncture. Nevertheless, existing object detection methods struggle with substantial computational demands, high resource utilization, and reduced detection efficiency. These challenges make deployment on edge devices difficult and lead to suboptimal user experiences.

Methods
In this study, we have developed a lightweight model capable of real-time detection and classification of strawberry fruit, named the Strawberry Lightweight Feature Classify Network (SLFCNet). This innovative system incorporates a lightweight encoder and a self-designed feature extraction module called the Combined Convolutional Concatenation and Sequential Convolutional (C3SC). While maintaining model compactness, this architecture significantly enhances its feature decoding capabilities. To evaluate the model’s generalization potential, we utilized a high-resolution strawberry dataset collected directly from the fields. By employing image augmentation techniques, we conducted experimental comparisons between manually counted data and the model’s inference-based detection and classification results.

Results
The SLFCNet model achieves an average precision of 98.9% in the mAP@0.5 metric, with a precision rate of 94.7% and a recall rate of 93.2%. Notably, SLFCNet features a streamlined design, resulting in a compact model size of only 3.57 MB. On an economical GTX 1080 Ti GPU, the processing time per image is a mere 4.1 ms. This indicates that the model can smoothly run on edge devices, ensuring real-time performance. Thus, it emerges as a novel solution for the automation and management of strawberry harvesting, providing real-time performance and presenting a new solution for the automatic management of strawberry picking.
Knowledge, attitudes, practices, and vaccination coverage of medical students toward hepatitis B virus in North Sudan, 2023
Authors: Mohamed Osama M.I. , Mohammedali Hassan S.H. , Mohamed Shimaa N.A. , Ahmed Hussein A.S. , Mohamedsalih Alaa A.M. , Abdalgani Ola M.A. , Mohammedosman Tebian A.A. , Ali Alaa A.A. , Ali Thuiba A.H. , Amin Othman N.O. , Issak Mohamed A. , Abdelaziz Mohamed O. 
Published: January 2025

Background
Hepatitis B virus (HBV) is a global health issue, particularly among healthcare personnel, including students because of its occupational exposure pattern. Healthcare Workers and medical students are recommended to have better knowledge, attitudes and good practices and vaccination toward infection control in general and HBV in particular. This study aimed to assess the knowledge, attitudes, and practices of medical students from North Sudan regarding HBV and its vaccination coverage.

Methods
A cross-sectional study was conducted from January to June 2023 among medical students in North Sudan. Data were collected using a structured scale using online Google Forms. Descriptive and comparative analyses were performed using SPSS version 26. Statistical significance was set at p ≤ 0.05.

Results
A total of 426 medical students were included in the study. The majority had good knowledge about HBV (86%) and its transmission methods (77%). The majority showed a favorable attitude (77%). The practice score was however very low (15.5%). Older age and advanced academic level were significantly associated with good knowledge (aOR: 3.9; CI 95% [3.69–12.92]; p = 0.016, and aOR: 2.6; CI 95% [1.16–6.15]; p = 0.020, respectively). Only a third of the students were vaccinated (33.0%), with only a few of them received complete doses (18.6%).

Conclusion
Students from medical colleges in North Sudan had good knowledge and favorable attitudes toward HBV. However, good practice was low. Older age and advanced academic level were significantly associated with knowledge level. Vaccination coverage was also low among the students in this study.
The inter-trial and inter-session reliability of Theia3D-derived markerless gait analysis in tight versus loose clothing
Authors: Augustine Sylvia , Foster Richard , Barton Gabor , Lake Mark J. , Sharir Raihana , Robinson Mark A. 
Published: January 2025

Background
Gait analysis is traditionally conducted using marker-based methods yet markerless motion capture is emerging as an alternative. Initial studies have begun to evaluate the reliability of markerless motion capture yet the evaluation of different clothing conditions across sessions and complete evaluation of the lower limb and pelvis reliability have yet to be considered. The aim of this study was to evaluate the inter-trial, inter-session and inter-session-clothing variation and root mean square differences between tight- or loose-fitting clothing during walking.

Method
Twenty-two healthy adult participants walked along an indoor walkway whilst eight video cameras recorded their gait in either tight- or loose-fitting clothing. A commercial markerless motion capture system (Theia3D) provided gait kinematics for evaluation.

Results
Reliability results showed average inter-trial variation of <2°, inter-session variation of <3° and inter-session-clothing variation <3.5°. Root mean square differences (RMSD) between clothing conditions were <2°.

Discussion
Pelvis variations were smaller than those at the hip, knee and ankle. Our results showed smaller variation than in previous studies which may be due to updates to software. The demonstration of the reliability of markerless motion capture for gait analysis in healthy adults should prompt further evaluation in clinical conditions and reconsideration of multi-assessor marker-based gait analysis protocols, where variation is highest.
Basis of single-seed formation in chestnut: cytomorphological observations reveal ovule developmental patterns of Castanea henryi
Authors: Qiu Qi , Tian Xiaoming , Wu Guolong , Wu Juntao , Yuan Deyi , Fan Xiaoming 
Published: January 2025

Background
Many plants, including those commonly found in the Fagaceae family, produce more flowers and ovules than mature fruits and seeds. In Castanea henryi, an ovary contains 16–24 ovules, but only one develops into a seed. The other ovules abort or otherwise fail to fully develop, but the reason for this is unknown. Such a strict reproductive screening mechanism is rare in plants.

Methods
In this study, controlled pollination scheme were adopted, and conventional paraffin embedding and semi-thin sectioning techniques, followed by microscopy, were used for cytological studies of ovule development in C. henryi.

Results
Pollination affected not only the process of ovule development, but also the proportion of ovules that formed mature embryo sacs. Approximately 53.53% of the ovules in the pollinated treatment developed normally, while only 16.55% of the ovules in the unpollinated treatment developed into mature embryo sacs with a seven-cell, eight-nucleated structure. Failure to form mature embryo sacs and the abnormal divisions of the zygote, respectively, were the reasons for the pre- and post-fertilization ovule failures. Our findings not only provide basic information on the reproductive biology and also information on seed production of C. henryi.
Importance of Rodents and Bandicoots in the diet of the Tasmanian Masked Owl
Authors: Todd Michael K. , Kavanagh Rodney P. , Spencer Chris P. , Bell Phil J. , Mooney Nick J. , Munks Sarah A. 
Published: January 2025

ABSTRACT
The food requirements of owls are critical to their conservation management. This study quantified the diet of the Tasmanian Masked Owl Tyto novaehollandiae castanops at 17 sites in eastern Tasmania, through the examination of regurgitated pellets. Mammals dominated the diet at all but one of the sites, with introduced rodents (mostly introduced Black Rat Rattus rattus and House Mouse Mus musculus) prominent in the diet at all sites. Bandicoots (mostly the Eastern Barred Bandicoot Perameles gunnii) were an important food item in diet collections south of Hobart. There was a wider range of larger-sized mammals in the diet of the Tasmanian Masked Owl than is usually found in the diet of the mainland Australian Masked Owl Tyto novaehollandiae. The prey species most common in the diet appears to vary across Tasmania and the findings suggest there is a focus on particular food sources at a particular locality. Prey partitioning between the sexes may account for some of this variation since this owl has a large degree of sexual dimorphism by size.
van der Waals Doping and Room Temperature Resonant Tunneling Observed in Black Phosphorus/Germanium Sulfide Transistors
Authors: Alhazmi Abrar , Alolaiyan Olaiyan , Alharbi Majed , Alghamdi Saeed , Alsulami Awsaf , Alamri Faisal , Albawardi Shahad , Aljalham Ghadeer , Alsaggaf Sarah , Alhamdan Khalid , Amer Moh. R. 
Published: December 2021

Abstractvan der Waals semiconductors have proven to be exceptional for electronic and photonic applications. Although most research is extensively focused on some transition metal dichalcogenides materials (MX2) such as MoS2, WS2, WSe2, and MoSe2, studies on 2D metal monochalcogenides such as germanium sulfide (GeS) has been widely under investigated, mainly due to the high contact resistance GeS devices exhibit. Here, a van der Waals field‐effect transistor (VdW‐FET) based on GeS is investigated and resonant tunneling behavior is shown at room temperature due to VdW doping via black phosphorus (BP), evident by the observation of multiple decades of negative differential resistance (NDR) during doping transient state. These NDR decades are caused by confinement of carriers inside the double barrier quantum well, which allows tunneling to occur for discrete energy levels. Moreover, a noticeable conductivity switch from a low p‐type to a high n‐type is observed, with a conductivity enhancement of 2 orders of magnitude compared to pristine GeS devices. The underlying mechanism behind the observed NDR and the conductivity switch is discussed and it is shown that these phenomena are likely caused by phosphorus doping due to BP sublimation, evident by the detected P‐Ge Raman peak in the measured Raman spectra. The results can open doors for electrical oscillators and switching devices for the next generation of nanoelectronics.
Substrate Viscoelasticity Amplifies Distinctions between Transient and Persistent LPS‐Induced Signals
Authors: Zhou Yu‐Wei , Wu Yu 
Published: December 2021

AbstractMacrophages settle in heterogeneous microenvironments rendered by other cells and extracellular matrices. It is well known that chemical stimuli direct macrophage behavior; however, the contributions of viscosity, which increases in inflammatory tissues but not in tumors, are ignored in immune responses including effective activation and timely attenuation. This paper demonstrates that transient lipopolysaccharide (LPS)‐treated macrophages benefit from elastic substrates, whereas viscoelastic substrates with similar storage moduli support the inflammatory responses of macrophages under persistent stimulations and consequently amplify the distinctions between the transient and persistent LPS‐induced transcriptional programs. Actin filaments (F‐actin) fluctuate in line with transcriptional profiles and can be mathematically predicted by a clutch‐like model. Moreover, viscosity modifies immune responses through transcription factors NF‐κB and C/EBPδ, which act as switches discriminating transient and persistent infections. Interestingly, enhanced immune responses, consistent with the lower activated states, are attenuated promptly by the actin nucleation‐related translocation of ATF3 to nuclei. These findings suggest that the substrate viscoelasticity induces more intense inflammation only in the case of persistent infection and promotes more sensitively perceiving the duration of infection through the F‐actin correlated transcription factors. In addition, it may facilitate the cognition of immune response in inflammatory and cancerous microenvironments and have a wide range of applications in inflammatory regulations.
Tumor‐Microenvironment‐Activatable Polymer Nano‐Immunomodulator for Precision Cancer Photoimmunotherapy
Authors: Liu Jing , He Shasha , Luo Yingli , Zhang Yue , Du Xiaojiao , Xu Cheng , Pu Kanyi , Wang Jun 
Published: December 2021

AbstractCancer nanomedicine combined with immunotherapy has become a promising strategy for treating cancer in terms of safety and potency; however, precise regulation of the activation of antitumor immunity remains challenging. Herein, a smart semiconducting polymer nano‐immunomodulator (SPNI), which responds to the acidic tumor microenvironment (TME), for precision photodynamic immunotherapy of cancer, is reported. The SPNI is self‐assembled by a near‐infrared (NIR)‐absorbing semiconducting polymer and an amphipathic polymer conjugated with a Toll‐like receptor 7 (TLR7) agonist via an acid‐labile linker. Upon arrival at tumor site, SPNI undergoes hydrolysis and triggers an efficient liberation of TLR7 agonist in response to the acidic TME for dendritic cell activation. Moreover, SPNI exerts photodynamic effects for direct tumor eradication and immunogenic cancer cell death under NIR photoirradiation. The synergistic action of released immunogenic factors and acidic‐TME‐activated TLR7 agonist can serve as an in situ generated cancer vaccine to evoke strong antitumor activities. Notably, such localized immune activation boosts systemic antitumor immune responses, resulting in enhanced cytotoxic CD8+ T infiltration to inhibit tumor growth and metastasis. Thereby, this work presents a general strategy to devise prodrug of immunotherapeutics for precise regulation of cancer immunotherapy.
Tough, Transparent, 3D‐Printable, and Self‐Healing Poly(ethylene glycol)‐Gel (PEGgel)
Authors: Wang Zhenwu , Cui Haijun , Liu Modan , Grage Stephan L. , Hoffmann Maxi , Sedghamiz Elaheh , Wenzel Wolfgang , Levkin Pavel A. 
Published: December 2021

AbstractPolymer gels, such as hydrogels, have been widely used in biomedical applications, flexible electronics, and soft machines. Polymer network design and its contribution to the performance of gels has been extensively studied. In this study, the critical influence of the solvent nature on the mechanical properties and performance of soft polymer gels is demonstrated. A polymer gel platform based on poly(ethylene glycol) (PEG) as solvent is reported (PEGgel). Compared to the corresponding hydrogel or ethylene glycol gel, the PEGgel with physically cross‐linked poly(hydroxyethyl methacrylate‐co‐acrylic acid) demonstrates high stretchability and toughness, rapid self‐healing, and long‐term stability. Depending on the molecular weight and fraction of PEG, the tensile strength of the PEGgels varies from 0.22 to 41.3 MPa, fracture strain from 12% to 4336%, modulus from 0.08 to 352 MPa, and toughness from 2.89 to 56.23 MJ m–3. Finally, rapid self‐healing of the PEGgel is demonstrated and a self‐healing pneumatic actuator is fabricated by 3D‐printing. The enhanced mechanical properties of the PEGgel system may be extended to other polymer networks (both chemically and physically cross‐linked). Such a simple 3D‐printable, self‐healing, and tough soft material holds promise for broad applications in wearable electronics, soft actuators and robotics.
Critical Review on Low‐Temperature Li‐Ion/Metal Batteries
Authors: Zhang Nan , Deng Tao , Zhang Shuoqing , Wang Changhong , Chen Lixin , Wang Chunsheng , Fan Xiulin 
Published: December 2021

AbstractWith the highest energy density ever among all sorts of commercialized rechargeable batteries, Li‐ion batteries (LIBs) have stimulated an upsurge utilization in 3C devices, electric vehicles, and stationary energy‐storage systems. However, a high performance of commercial LIBs based on ethylene carbonate electrolytes and graphite anodes can only be achieved at above −20 °C, which restricts their applications in harsh environments. Here, a comprehensive research progress and in‐depth understanding of the critical factors leading to the poor low‐temperature performance of LIBs is provided; the distinctive challenges on the anodes, electrolytes, cathodes, and electrolyte–electrodes interphases are sorted out, with a special focus on Li‐ion transport mechanism therein. Finally, promising strategies and solutions for improving low‐temperature performance are highlighted to maximize the working‐temperature range of the next‐generation high‐energy Li‐ion/metal batteries.
Mediating Colloidal Quantum Dot/Organic Semiconductor Interfaces for Efficient Hybrid Solar Cells
Authors: Kim Byeongsu , Baek Se‐Woong , Kim Changjo , Kim Junho , Lee Jung‐Yong 
Published: December 2021

AbstractEmerging semiconducting materials including colloidal quantum dots (CQDs) and organic molecules have unique photovoltaic properties, and their hybridization can result in synergistic effects for high performance. For realizing the full potential of CQD/organic hybrid devices, controlling interfacial properties between the CQD and organic matter is crucial. Here, the electronic band between the CQD and the polymer layers is carefully modulated by inserting an interfacial layer treated with several types of ligands. The interfacial layer provides a cascading conduction band offset (ΔEC), and reduces local charge accumulation at CQD/polymer interfaces, thereby suppressing bimolecular recombination; a thin thiol‐treated interfacial layer (≈6 nm) decreases shallow traps, resulting in higher short‐circuit current (JSC) and fill factor of hybrid solar cells. Based on these results, a high performance CQD/polymer hybrid solar cell is introduced that demonstrates a power conversion efficiency of 13.74% under AM 1.5 solar illumination. The hybrid device retains more than 90% of its initial performance after 402 days under ambient conditions.
Characterization of bone homeostasis in individuals affected by cardio‐facio‐cutaneous syndrome
Authors: Leoni Chiara , Viscogliosi Germana , Onesimo Roberta , Bisanti Cristian , Massese Miriam , Giorgio Valentina , Corbo Fabio , Tedesco Marta , Acampora Anna , Cipolla Clelia , Dell'Atti Claudia , Flex Elisabetta , Gervasoni Jacopo , Primiano Aniello , Rigante Donato , Tartaglia Marco , Zampino Giuseppe 
Published: December 2021

AbstractCardio‐facio‐cutaneous syndrome (CFCS) is a rare disorder characterized by distinctive craniofacial appearance, cardiac, neurologic, cutaneous, and musculoskeletal abnormalities. It is due to heterozygous mutations in BRAF, MAP2K1, MAP2K2, and KRAS genes, belonging to the RAS/MAPK pathway. The role of RAS signaling in bone homeostasis is highly recognized, but data on bone mineral density (BMD) in CFCS are lacking. In the present study we evaluated bone parameters, serum and urinary bone metabolites in 14 individuals with a molecularly confirmed diagnosis of CFCS. Bone assessment was performed through dual X‐ray absorptiometry (DXA); height‐adjusted results were compared to age‐ and sex‐matched controls. Blood and urinary bone metabolites were also analyzed and compared to the reference range. Despite vitamin D supplementation and almost normal bone metabolism biomarkers, CFCS patients showed significantly decreased absolute values of DXA‐assessed subtotal and lumbar BMD (p ≤ 0.05), compared to controls. BMD z‐scores and t‐scores (respectively collected for children and adults) were below the reference range in CFCS, while normal in healthy controls. These findings confirmed a reduction in BMD in CFCS and highlighted the importance of monitoring bone health in these affected individuals.