bluuebunny/crossref_metadata_2025_split huggingface dataset:
Falso negativo en serología de VHC debido a interferencia por crioglobulinas
Authors: Recio Comí Gemma , Molina Clavero Carmen , Calabuig Ballester Sandra , Benavent Bofill Clara , Picó-Plana Ester , Martín Grau Carla , Gutiérrez Fornés Cristina , Sans Mateu Mᵃ Teresa 
Published: February 2021

Resumen

Objetivos
Las crioglobulinas (CG) son proteínas séricas que precipitan en frío in vitro. Se sabe que las CG causan interferencias analíticas en diversos tipos de análisis clínicos, lo que se traduce en resultados incorrectos. Presentamos el caso de una paciente diagnosticada erróneamente de crioglobulinemia esencial debido a la interferencia de las CG en la serología del virus de la hepatitis C (VHC).

Presentación del caso
Es el caso de una paciente edad avanzada edad con fallo renal agudo que requirió hemodiálisis urgente. Ante la ausencia de infecciones u otras patologías asociadas a la producción de CG, se estableció el diagnóstico de fracaso renal agudo causado por una crioglobulinemia esencial. Sin embargo, se obtuvo un resultado positivo inesperado al analizar la carga viral del VHC. De este modo, se sospechó de la presencia de una infección por VHC, con resultado falso negativo en la serología, causado por la interferencia in vitro de las CG. Esto se confirmó al repetir la serología en suero calentado a 37 °C. Finalmente, se estableció el diagnóstico de crioglobulinemia secundaria a infección por VHC.

Conclusiones
Este caso evidencia que la presencia de CG en sangre puede interferir en la correcta interpretación de los resultados de diversos tipos de análisis clínicos. La identificación de las CG y el tratamiento previo del suero son cruciales a la hora de evitar resultados incorrectos y establecer un diagnóstico certero.
Amino acid metabolism disorders and PAH gene mutations in Southeastern Anatolia Region
Authors: Öz Özlem , Akbulut Emiş Deniz , Karadağ Müjgan Ercan , Gönel Ataman , Koyuncu İsmail 
Published: February 2021

Abstract

Objectives
Inborn errors of metabolism are generally autosomal recessive inherited disorders. The incidence and genetic features of neonatal metabolic disorders vary significantly by regions and populations. In this study, we aimed to determine the amino acid metabolism disorders and evaluate the genetic test results of these patients retrospectively.

Methods
The blood samples collected from heel blood and dried on filter cards in the neonatal screening program, were analyzed for amino acid metabolism disorders by (LC)-MS/MS method. Patients with suspected metabolic diseases were diagnosed with NGS method.

Results
Amino acid metabolism disorders were detected in 66 of 2,104 patients who were screened for suspected neonatal metabolic disorders. Sixty-two of 66 patients were diagnosed with phenylketonuria, the rest of them were diagnosed with tyrosinemia type I, arginosuccinate lyase deficiency, citrullinemia type 1 and Maple Tree syrup disease. The most common PAH gene mutations were c.1208C>T (A403V).

Conclusion
Phenylketonuria was the most common disease among amino acid metabolism disorders in Şanlıurfa. There were different allele frequencies compared to the PAH mutations reported in previous studies. This may be due to the different characteristics of the populations and also the high rate of consanguineous marriage in our region.
The Current State of Transatlantic Relations: Déjà vu All Over Again?
Authors: Csizmazia Gábor 
Published: February 2021

Abstract
While the United States and Europe share a set of basic values and interests, debates across the Atlantic do repeatedly occur, particularly since the end of the Cold War. Transatlantic relations under the Trump Administration have experienced noticeable political tensions that were last witnessed under the Bush Administration in the early years of the millennium. There is a sense of déjà vu in Europe, given that despite Donald J. Trump’s unusual rhetoric, the issues in hand are not necessarily new. Washington’s take on the international order and transatlantic relations is best described by the concept of conservative internationalism, which differs from other U.S. foreign policy approaches yet continues to be in contrast with the more liberal views in Europe.
Political and Economic Feasibility of Contracted American Liquefied Natural Gas for Energy Security in Poland and the Baltic States – Can the American Government Help?
Authors: Kulander Christopher 
Published: February 2021

Abstract
At the heart of the European Union (“EU”) energy policy is energy security. Energy security is maintained, in part, by a diversification of supply. Despite the fact that the EU has prioritized diversification, its dependency on Russian natural gas has increased in recent years. Contemporaneously, the politicalrelationship between the EU and Russia has worsened. Construction of NordStream 2(“NS2”) will further establish Russia as the dominant supplier of natural gas to the EU while lessening the diversification of its energy supply. To further the EU’s stated goals of energy diversification and security, another steady source of natural gas imports for the countries along the Baltic Sea is needed. LNG importation assets in Poland and the Baltic states exist for this purpose. Unlike other EU members, these countries have demonstrated the economic and political will to curb the coercive influence ofRussian natural gas imports. America is awash in natural gas, with plenty for export and can sendincreasing volumes of LNG worldwide. In contrast to other sources, America is well located to supply Europe with secure LNG, and its importation should be a shared goal of the EU and America. Despite the desire of some American statesmen to use the “shale gas revolution” to further U.S. geopolitical goals; however, the U.S. hydrocarbon industry (unlike in Russia) is overwhelmingly controlled by private landowners and industry. The goal ofthe American, Polish, and the Balticstates should therefore be narrowly focusedon establishing free trade agreements and the encouragement of longer -term contractual relationships between America and Poland and the Baltic states.
Desee, Richard. (2019). Climate change and the future of democracy. Massachusetts, Estados Unidos: Editorial Springer
Authors: Villalobos Jiménez Alonso 
Published: February 2021

Reseña del libro "Climate change and the future of democracy", escrito por Richard Deese, Doctor en Historia y profesor de la Universidad de Boston. Reseña preparada por el profesor de la Escuela de Ciencias Políticas y Doctor en Ciencias Sociales por la Universidad de Potsdam (Alemania), Sr. Alonso Villalobos Jiménez.
Imaginario y simbología del agua en seis poemas de temática clásica de Jorge Luis Borges
Authors: Valenciano Minor Herrera 
Published: February 2021

El simbolismo del agua y el imaginario surgido entorno a esta constituyen una de las manifestaciones literarias más extensamente explotada por los autores latinoamericanos del Boom, pues este elemento teje una serie de relaciones intrincadas en las que se junta el mundo metafísico con el mundo físico; la consciencia con el inconsciente colectivo, la razón y la pasión.
El presente artículo muestra cómo el agua ocupa una posición esencial en algunos poemas de tema clásico (grecolatino) escritos por Jorge Luis Borges para desarrollar ideas como el olvido, la muerte, el tiempo y la discontinuidad, ya presentes en los imaginarios griego y romano (conocidos muy bien por el autor), y tan recurrentes en relatos épicos. Para tal fin se analizarán los poemas titulados Proteo, Brunanburh, En memoria de Angélica, Al espejo, Efialtes, publicados en el poemario titulado La rosa profunda (1975)y Heráclito, publicado en el poemario titulado La Moneda de Hierro (1976).
Risk of Exposure, Impact and Bio Safety Measure among Healthcare Workers in Covid19 Infection, In a Tertiary Care Teaching Hospital, Kolkata
Authors: Agarwal Dr. Urvashi , Deb Dr. Sujay Ranjan , Roy Dr. Arpan Dutta , Gupta Dr. Debkishore , Ghosh Dr. Sayantan , Kurian Dr. Berlin P , Shaji Jerin S , Paul Dr. Prolay 
Published: February 2021

Healthcare workers are the front liners in war against COVID 19 pandemic. Since this fight against the pandemic started, thousands of heath care workers have been infected with many paying the ultimate price with their lives in a bid to provide health care service to COVID 19 patients. Currently many are either in quarantine or in isolation. Still many are working with fear of virus and in under poor conditions without adequate protections. The potential for high exposure is generally higher in health care workers due to increased hospitalization, longer time exposure, failure to implement effective personal health protection, lack of training, monitoring of infection control protection mechanism. This has led to shortage of workforce in the health sector. Exposure to COVID 19 in the health care setting depends on the health care worker’s understanding of the infectious nature of the virus, the routes by which the virus is acquired, the techniques that are most hazardous and the safe working environment and practice. This work is therefore aimed at providing relevant information on the risk of exposure, the impact of virus on the health care workers and the required bio safety measures needed to keep the workers safe in the organization.
Broad Academic area of work: Service Quality Excellence in Health care
Keywords-: PPE (Personal protective equipments), BMW (Bio medical waste), donning and doffing (process of using and discarding PPEs), HCW (Health care workers), Nosocomial infection (Hospital acquired infection), Covid 19.
Церковнослов’янська лексика зі семантикою ‘Бог; Божа особа’ у староукраїнських текстах
Authors: ОСІНЧУК ЮРІЙ 
Published: February 2021

The present paper is based on materials of different genres and different styles of Ukrai- nian written monuments of the 16th and the 17th centuries (acts, court documents, wills, deeds, documents of church and school fraternities, chronicles, works of religious, polemi- cal and fiction, memos of scientific and educational literature, liturgical literature, episto- lary heritage, etc.) which are included in the source database of the Dictionary of Ukrainian language of the 16th century and the first half of the 17th century and its unique lexical card index, which is stored at the Ukrainian Language Department in the I. Krypiakevych Institute of Ukrainian Studies of the National Academy of Sciences of Ukraine (Lviv). The composition and structural organization of Church Slavonic lexemes meaning ‘God; God’s face’ as well as their origin and history are studied.It was found that the register of this vocabulary included more than fifty phonetic and graphic Church Slavonic elements expressing the concept of ‘God; God’s face’ different in word-forming structure. The main attention is paid to the etymological analysis of the studied tokens, which was primarily to clarify their semantic etymon. It is established that the analyzed Church Slavonicisms are mostly semantic loans from the Greek language, which preserved their semantics from ancient times to the Old Ukrainian period.It is observed that some studied tokens often act as core components of various two-, three-, or four-membered lexicalized phrases. The most active multifunctional core com- ponent was the token Lord. It is established that fixed phrases and phraseologisms are of different types in structure, mostly two-component noun + adjective phrases (sporadically, there are other lexical-grammatical models, too: “noun + noun”, “preposition + adjective”). Much less observable are three-component formations (“noun + verb + pronoun“, “verb + pronoun + noun“) and four-component models (“verb + preposition + pronoun + noun”).It was found that the Church Slavonic words attested in the Ukrainian memos of the 16th and the 17th centuries did not undergo significant semantic changes in the process of formation of religious vocabulary. Some Church Slavonicisms have gone through a partial semantic modification, and some have acquired new semantics due to fixed phrases. Some words that point to God’s face are characterized by polysemy and synonymy.The evolution of the analyzed Church Slavonicisms is different. Some of them have survived to our time and are actively used in the Ukrainian literary language or dialects, while others function only in a special area: in the church practice of the Byzantine rite (Orthodox Church of Ukraine, Ukrainian Greek Catholic Church).
Impact of Lactobacillus cultures on production of B-vitamins, organic acids and biotransformation of soy isoflavones
Authors: Das S. , Mishra B.K. , Hati S. 
Published: February 2021

AbstractIn the study, four potent Lactobacillus cultures of L. rhamnosus K4E, L. plantarum RD7, L. fermentum K7, and L. fermentum K16 were considered for the production of B-vitamins, organic acids and biotransformation of soy isoflavones. L. plantarum RD7 showed the highest B2 production (0.84 μg mL−1) after 36 h, while L. fermentum K16 exhibited maximum B12 production (0.084 μg mL−1) after 12 h. L. rhamnosus K4E produced 0.24 μg mL−1 of folate after 12 h. Highest production of lactate (16.43 μg mL−1) and acetate (5.86 μg mL−1) was reported by L. rhamnosus K4E. L. plantarum RD7 showed maximum butyrate (0.253 μg mL−1) production compared to the other cultures. The highest bioconversion of soy aglycones was reported by L. rhamnosus K4E with 55.43% for daidzein and 72.30% for genistein, during soymilk fermentation. These potent cultures have a potential to be used as functional starter cultures for the production of functional fermented soy foods.
Reduced graphene oxide-chitosan flexible nanocomposites for efficient bacteria capture and photothermal ablation
Authors: Budimir Milica , Kleut Duška , Markovic Biljana Todorovic , Boukherroub Rabah 
Published: February 2021

AbstractOne of the major public health concerns today is bacterial infection-associated diseases. Traditional antibacterial therapies are becoming less efficient because frequent and inadequate use of antibiotics has caused mutations in bacteria that led to many antibiotic-resistant bacterial strains. It is, therefore, crucial to develop novel antibacterial materials and strategies that will successfully combat both gram-positive and gram-negative bacteria. In the present study, we will demonstrate a simple and efficient method for bacteria capture and elimination through photothermal ablation. The developed material consists of a flexible Kapton substrate, coated with reduced graphene oxide-chitosan (rGO-CS) thin films. Reduced graphene oxide has strong absorption in the near-infrared (NIR) region, while chitosan has the ability to bind bacteria through electrostatic interactions. The K/rGO-CS device proved to capture and efficiently eradicate both planktonic Gram-positive Staphylococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli) bacteria after 10 min of NIR (980 nm) irradiation.
İŞ KARAKTERİSTİKLERİNİN BİREYSEL İŞ PERFORMANSI ÜZERİNDEKİ ETKİSİNİ BELİRLEMEYE YÖNELİK SAĞLIK ÇALIŞANLARI ÜZERİNDE BİR ARAŞTIRMA
Authors: KAYA Metin , DİNÇ ELMALI Esra 
Published: February 2021

Bu araştırmanın amacı, iş karakteristiklerinin bireysel iş performansı üzerindeki etkisini özellikle sağlık çalışanları açısından belirlemektir. Zor şartlar altında çalışan sağlık personelinin hangi performans türü üzerinde hangi iş karakteristiğinin etkili olduğu önemli bir bilgidir. Araştırmada veri toplama yöntemi olarak anket tekniğinden yararlanılmıştır. Araştırma, kamu ve özel hastanelerden tesadüfi olarak seçilen 527 katılımcı ile gerçekleştirilmiştir. Açıklayıcı faktör analizi ve çoklu doğrusal regresyon analizi sonuçlarına göre; iş karakteristiklerinin alt boyutlarından işin kimliği ve arkadaşlığın bireysel iş performansının tüm alt boyutlarını pozitif yönde etkilediği görülmüştür. Ayrıca özerkliğin zarar verici iş davranışını negatif yönde etkilediği, geri bildirimin görev performansını pozitif yönde etkilediği, beceri çeşitliliğinin ise görev ve içerik performansını pozitif yönde etkilediği sonucuna ulaşılmıştır.
JEL Kodları: D23, M12, M54
La Educación para los Derechos Humanos una necesidad apremiante en la actualidad
Authors: Bastidas Patiño Adriana del Pilar 
Published: February 2021

Antes de desarrollar esta editorial, quiero agradecer la deferencia que han tenido con la suscrita para participar en esta nueva edición de la Revista Investigium-IRE: Ciencias Sociales y Humanas. Es grato poder contribuir con el serio trabajo que viene desarrollando la Institución Educativa que otrora me permitió comprender que la misión que Dios me ha encomendado en esta vida; es poner a disposición de la educación mi profesión.
CHARACTERISTICS OF BREAD DOUGH MADE WITH THE USE OF VARIOUS MILLET FLOURSCHARACTERISTICS OF BREAD DOUGH MADE WITH THE USE OF VARIOUS MILLET FLOURS
Authors: Moeini Afsaneh , Masoud Shafafi Zenoozian Masoud Shafafi , Karazhiyan Hojjat , Rad Amir Hossein Elhami , Nia Ahmad Pedram 
Published: February 2021

Millets are gaining attention due to their many advantages in cultivation and overall nutritional benefits. Research has been carried out to explore the nutritional properties of various millets. However, the use of millets in today’s food processing is minimal as compared to wheat. Three minor millets, namely foxtail, proso, and pearl millets grown in Iran were used in this study. The water absorption characteristics and hardness of these millets have been investigated. The effect that millet flours incorporated in dough have on its rheology has been studied and compared with the effect of wheat on dough rheology. The moisture content of millets increased with an increase in the water temperature, and a regular increase in the water absorption capacity, too, was observed as the temperature rose. The hardness of the millet decreased with an increase in the moisture content of the grains. Pearl millet has been found to have the lowest hardness irrespective of the steeping time and temperature. Incorporation of millet in the dough adversely affected the dough rheology in terms of workability and baking quality. Proso millet highly negatively affected the dough rheology in terms of dough hardness, stability, and dynamic rheological properties. This research highlights the possibility to predict the water absorption characteristics of millet grains to be used to optimise the conditions under which millets are steeped in various bioprocessing operations. It is supposed that on performing proper baking trials to compare the properties of composite flours made from these millets, the results of the rheological studies will prove beneficial and the rheological properties and behaviour will be accurately correlated when the food is applied practically.
Miyofasiyal ağrı sendromunda tetik nokta enjeksiyonu ile tetik nokta enjeksiyon artı kinezyo bantlamanın etkinliğinin karşılaştırılması
Authors: YILMAZ Ebru 
Published: February 2021

Amaç: Miyofasiyal ağrı sendromunun (MAS) altta yatan periferik ve merkezi nöral mekanizmaları olan kompleks patolojisi nedeniyle kronik dönemdeki tedavisinde zorluklara neden olmaktadır. MAS'da en yaygın kullanılan tedavi yöntemi olan tetik nokta enjeksiyonu (TNE) ile belli bir düzeyde ağrı giderilmesine rağmen, bu etki kısa bir süre devam eder ve genellikle birkaç tedavi seansı gerektirir. MAS tedavisine multidisipliner bir yaklaşım en yararlı tedavi seçeneği gibi görünmektedir ve birkaç çalışmada trapezius kasında MAS tedavisinde KT’nin faydalı etkisi olduğunu desteklemektedir. Bu çalışmanın amacı, trapezius kasında MAS tedavisinde tek başına TNE'nin ve TNE ile KT kombinasyonunun etkinliğini karşılaştırmaktır.
Yöntem: MAS'lu 40 hasta rastgele iki gruba ayrıldı (grup başına 20 hasta): Grup 1: TNE (1 ml betametazon dipropionat+3 ml lidokain+1 ml salin); Grup 2: TNE artı KT. Başlangıçta ve tedaviden 1-3 ay sonra görsel analog skala (VAS) ve boyun yetmezliği indeksi (NDI) kaydedildi.
Bulgular: Grup 1 ve Grup 2'de hastaların yaş ortalaması sırasıyla 45.9±12.49 ve 47.0±14.34 idi (Tablo 1). Her iki grupta da 1. ve 3. aylardaki VAS ve NDI skorları başlangıç değerine göre anlamlı olarak azalmasına rağmen 3. ayda VAS ve NDI skorları Grup 2'de Grup 1'e kıyasla anlamlı olarak daha düşüktü (p
Abandono do acompanhamento de saúde infantil em serviços de saúde: revisão sistemática
Authors: Machado Cruz Shibukawa Bianca , Patricio Rissi Gabrieli , Tognollo Borota Uema Roberta , Garcia Lopes Merino Maria de Fátima , Higarashi Ieda Harumi 
Published: February 2021

Objetivo: analisar evidências das razões dos familiares que levam ao abandono do acompanhamento de saúde do recém-nascido, lactentes e pré-escolares em serviços de saúde infantil. Método: revisão sistemática de evidências qualitativas nas fontes de informação: Web of Science, Science Direct, CINAHL, SCOPUS, BDENF, PUBMED, EMBASE, LILACS, ASSIA, Sociological abstracts, Open Gray, Google Acadêmico, Dart-e, Cybertesis, Open Thesis, PeerJ Prepint, MedRxiv, BioRxiv e PsycINFO. Os títulos e resumos serão examinados por dois revisores independentes e os estudos relevantes serão recuperados na íntegra. A síntese de dados será executada pela extração de todas as descobertas de todos os trabalhos incluídos, desenvolvimento de categorias para descobertas semelhantes e desenvolvimento de descobertas sintetizadas de pelo menos duas categorias. As descobertas qualitativas da pesquisa, serão agrupadas com a abordagem de meta-agregação. Os resultados finais sintetizados serão classificados e apresentados em um resumo dos resultados.
Comparison of preoperative high resolution computerized tomography of temporal bone with intra-operative findings in patients with cholesteatoma
Authors: Pilakkal Abdunnasar Moodem , Pillai Santhi Thankappan , Kunhanakkal Asif Iqbal 
Published: February 2021

<p class="abstract"><strong>Background:</strong> Aim was to study the correlation between high resolution computed tomography (HRCT) scan and intraoperative findings during surgery in cases of chronic otitis media with cholesteatoma.</p><p class="abstract"><strong>Methods:</strong> This was a descriptive study conducted on 72 patients with acquired cholesteatoma at Govt TD Medical College, Alappuzha for a period of 18 months. All the patients were subjected to HRCT of the temporal bone. Radiological correlation was done with the intra-operative findings. Sensitivity, specificity, positive and negative predictive values were calculated. </p><p class="abstract"><strong>Results:</strong> Total 24 (33.3%) patients had holotympanic cholesteatoma, 21 (29.2%) had involvement of the attic alone and 16 (22.2%) had attic and antrum involved. 100% correlation was found with bony wall erosions, whereas 96.9% and 75% sensitivity were noted in incus and stapes erosions respectively. 100% specificity was obtained in facial canal and sinus plate erosion, while a specificity of 96.9% in tegmen erosion and 98% in were seen in malleus erosion. By chi square test the difference in correlation was not significant (p value&gt;0.01). Good correlation was seen for lateral semicircular canal fistula. Contrast CT is more specific, but MRI with diffusion weighted sequences is the best in imaging cholesteatoma, especially residual lesions. </p><p class="abstract"><strong>Conclusions:</strong> Good correlation was found between HRCT scan and intra-operative findings in cases of cholesteatoma in relation to bony wall erosion of the surrounding structures. CT scan alone cannot differentiate soft tissue masses.</p>