bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bone scintigraphy and positron emission tomography in the early diagnosis of MRONJ
Authors: Pergolini Daniele , Mohsen Mohamed , Tenore Gianluca , Palaia Gaspare , Magnifico Lorenzo , Del Vecchio Alessandro , Romeo Umberto 
Published: February 2025

Abstract

Objectives
The aim of this study is to evaluate the bone scintigraphy (BS) and positron emission tomography (PET) in the early diagnosis of medication-related osteonecrosis of the jaws (MRONJ) and their possible use in the identification of patients at risk for MRONJ.

Material and methods
Thirty-one patients treated with ONJ-related drugs and who had undergone BS or PET for the evaluation of bone lesions were included in the study. The jaws of each patient were divided into four areas. For each area, the presence of pathological tracer uptake was evaluated and related to the eventual MRONJ development. Sensitivity, specificity, and predictive values of both techniques were determined. The latency from the finding of pathological tracer uptake in BS or PET to the clinical diagnosis of MRONJ and the odds ratio were also calculated.

Results
Sensitivity and specificity of BS for MRONJ prediction were, respectively, 83.3 and 87.5%. Positive and negative predictive values were, respectively, 73.2 and 92.8%. The odds ratio was 35. Sensitivity of PET was 33.3%, specificity was 94.9%, and positive and negative predictive values were 70.0 and 80.0%, respectively. The odds ratio was 9.333. All values were statistically significant.

Conclusions
BS and PET may be accurate techniques for an early prediction of MRONJ.
Semiotics of artificial intelligence: enunciative praxis in image analysis and generation
Authors: Dondero Maria Giulia 
Published: February 2025

Abstract
This paper explores the relation between images and databases in a twofold way. The first part examines image databases as sources for image computational analysis, while the second part studies image databases as sources for image generation (notably through the generative artificial intelligence model Midjourney). Image analysis and image generation will be analyzed through the concept of enunciative praxis. Traditionally, enunciative praxis concerns cultural transformations over the long term (the relation between sedimentation and innovation); in our case it will be used notably to study the generation of new images through old, traditional ones.
Sudden Unexpected Death and Alcohol Addiction: Case Report on Disulfiram Use
Authors: Kondratavičiūtė Gabija , Banionis Dalius , Laima Sigitas , Chmieliauskas Sigitas , Vasiljevaitė Diana , Petreikis Paulius , Badaras Robertas 
Published: February 2025

Background: Disulfiram is a type of medication widely prescribed in order to cease alcohol consumption. When used with alcohol, the ‘disulfiram-alcohol reaction’ occurs, causing nausea and vomiting. Disulfiram blocks alcohol dissolving enzymes thus increasing acetaldehyde concentration and inducing the above-mentioned symptoms. These undesirable symptoms are similar to the side effects that occur to oncological patients after the administration of chemotherapy.Materials and methods: Descriptive research method was used. The literature focusing on alcohol, medications and drug consumption was reviewed.Case report: The primary abstinence at the beginning of treatment with Disulfiram does not guarantee that alcohol usage will not get manifested again at the further stages of treatment. Alcohol addiction forces patients to search for a way to avoid the unwanted reactions. Sometimes, patients tend to be quite ingenious while trying to suppress the arising side effects. In many cases, it involves the usage of additional medication.Conclusions: When alcohol addiction overpowers, the patient tries to reduce the undesirable symptoms and may even die if alcohol is combined with disulfiram. Death may occur due to the cardio and neurotoxic effects of acetaldehyde.
Experiences of Nursing Students Working with Nurses during Clinical Practice
Authors: Šulskytė Justė , Spirgienė Lina 
Published: February 2025

The aim of the study: to establish nursing students’ experiences of working as a team with nurses during clinical practice. Methods. The qualitative research was carried out between December 2023 and February 2024. 9 female students of the 4th year nursing programme at LSMU were interviewed. Approval for the study was obtained from the LSMU Bioethics Center (No. 2023-BEC2-396, 14 November 2023). Research results. Professional nurses were the key individuals who taught how to perform procedures, communicate with patients, encouraged professional improvement, and provided emotional support in difficult and stressful situations. The participants were pleased when the involved nurses were paying due attention to the process of training and showed the trainees from their own experience how to carry out procedures more effectively. The students positively commented on the nurses’ ability to teach students. According to the research participants, if the students themselves show initiative, nurses willingly involve them in critical situations. By motivating students, nurses can create a stronger bond with them, and, most importantly, encourage them to never give up, and to have more confidence in their own abilities. The experiences of nursing students depended on the course in which they were carrying out their clinical practice. Conclusions. Experiences in the clinical practice influence nursing students’ perceptions of the nursing profession and teamwork. Nursing students stated that they mostly worked in teams with nurses, learning by observing their actions and later trying out their own abilities in various nursing procedures.
Ориентализмы тематической группы «Сладкие блюда» в фразеологии южных славян (на фоне других языков)
Authors: Кузнецова И. В. 
Published: February 2025

Ориентализмы – слова разных групп тюркских, а также иранских и арабо-семитских языков. Язык османских турок был как источником заимствований, так и посредником проникновения ори-ентализмов (в первую очередь арабизмов и персизмов) в южнославянские языки-реципиенты. В статье анализируются устаревшие и активно употребляющиеся в наши дни на территории Южной Славии фразеологические единицы с компонентами ориентального происхождения, связанными с кухней Востока. Слова заимствовались вместе с реалиями – блюдами восточной кухни. Мы ограни-чились тематической группой «Сладкие блюда» (сахар, халва, рахат-лукум, пекмез, десерты из теста – пахлава, гурабия, мафиш, кадаиф и риса – сутлияш). Названия восточных сладостей вошли в язы-ки-реципиенты в результате языковой коммуникации, сопровождавшей диалог разных культур на протяжении нескольких веков. В статье приводятся некоторые лингвокультурологические и исто-рико-этимологические комментарии к фразеологическим единицам, а также толкование фразеоло-гических оборотов и компонентов, входящих в них. Это необходимо для понимания ментальности носителей того или иного языка, для ознакомления с культурным наследием народа.Материал исследования – данные словарей и интернет-источники. При обработке фразеологиче-ского материала применялись синхронно-описательный метод, метод анализа компонентов, метод лингвокультурологического анализа, прием выборки фразеологизмов из словарей и интернет-ре-сурсов. Привлечение фразеологического материала других языков (восточно- и западнославянских и неславянских) позволило выявить универсальность или национальную специфику анализируе-мой южнославянской фразеологической единицы. Фразеологический материал показывает, как в разные языки входили заимствования-ориентализмы восточной кухни, демонстрирует разный фразеологический потенциал восточных сладостей, ареальную проекцию фразеологизма (или от-сутствие таковой). В силу разных причин (исторических и существующих ныне) названия сладких блюд ориентальной кухни чаще встречаются в боснийских фразеологических единицах. Варианты фразеологизмов иллюстрируют параллельное использование в некоторых структурно-семантиче-ских моделях ориентализмов и славянизмов или германизмов. Фразеологизмы со «сладким» компо-нентом характеризуют как человека, так и внешний по отношению к нему мир.
Smear layer removal potential of a naturally occurring antioxidant: An in-vitro scanning electron microscopic study
Authors: Shenvi Suresh , Joshi Sonal B 
Published: February 2025

The primary objective of endodontic therapy is to thoroughly disinfect the root canal system. The smear layer formed during instrumentation presents a substantial impediment to optimal root canal disinfection, as it provides a medium for bacterial proliferation, hinders the penetration of disinfecting agents, and creates a physical barrier that undermines the efficacy of root canal sealers by obstructing the interface between the obturating core material and the dentinal tubules. Consequently, the removal of the smear layer is of utmost importance. This in vitro study assessed the efficacy of 20% N-acetyl-cysteine (NAC) and 17% ethylenediaminetetraacetic acid (EDTA) in removing the smear layer from root canal dentine. Ninety-two single-rooted teeth were instrumented and divided into two groups: 20% NAC for 1 minute, and 17% EDTA for 1 minute. Following irrigation, the samples were analyzed using scanning electron microscopy (SEM) to evaluate smear layer removal in the coronal, middle, and apical thirds of the root canals. No statistically significant difference was observed between 20% NAC and 17% EDTA in their ability to remove the smear layer across all sections of the root canal. 20% NAC demonstrates smear layer removal capability comparable to 17% EDTA as a final irrigant.
Single-visit MTA apexification: A progressive approach for immature teeth with Ellis Class IV fractures- case report
Authors: Balaji S , Panwar Neeraj Kant , Niharika Nishma , Stalin A Arivu , Dwivedi Viidii , Chaurasia Parth , Das Meghna 
Published: February 2025

Trauma to developing teeth can disrupt root formation, leading to an open apex and complicating endodontic treatment. Apexification is essential in managing immature non-vital teeth to induce a calcified apical barrier for effective obturation. Traditionally, calcium hydroxide has been the material of choice, but it presents challenges such as extended treatment time and risk of root fractures. Mineral trioxide aggregate (MTA) has emerged as a reliable alternative, offering faster treatment with fewer complications.A 12-year-old male presented with a history of trauma to the maxillary central incisors (teeth 11 and 21), resulting in Ellis Class IV fractures. The trauma occurred six months prior during a fall. Clinical examination revealed pulpal necrosis, and radiographs confirmed incomplete root formation with open apices. The patient underwent root canal therapy, including pulpal debridement and one-visit apexification with MTA to induce an apical barrier. The MTA was compacted at the apical ends of the canals to provide immediate sealing.Root canal obturation was successfully completed, and radiographic follow-up demonstrated satisfactory apical sealing. The patient experienced no post-operative complications, and long-term follow-up will be conducted to monitor root maturation and tooth stability.MTA provides an efficient, biocompatible alternative to calcium hydroxide in apexification, offering faster treatment and reduced risk of root fracture. One-visit apexification with MTA can be considered a viable treatment for non-vital immature permanent teeth with open apices.
Customised vaginal dilator: A case report
Authors: Srivastava Ayush , Gopi Anup 
Published: February 2025

Vaginal agenesis, which occurs in approximately 1 in every 5,000 to 7,000 female births. In place of the vagina, there is typically a small pouch or dimple that is 1 to 4 cm in depth. The treatment may either be a surgical or non-surgical method, but the chosen method needs to be tailored to the individual’s needs. The non-surgical creation involves the dilator expansion methods that have been in use for decades. This involves the use of graduated dilators to gradually increase the caliber to a predetermined size.
Conventional and Molecular Characterization Based Microbial Assessment of Street Vended (Vada pav) Samples from Anand City, Gujarat, India
Authors: Mall D.P. , Patel V.H. , Subhash R. 
Published: February 2025

Background: Street foods offer convenient meal options for the consumer, but pose safety concerns if not handled or served with proper hygiene. The purpose of the present study was the microbial evaluation of street vended Vada pav samples sold at popular locations in Anand city using the conventional culture technique and molecular characterization via Polymerase Chain Reaction.
Methods: Duplicate samples were collected from seven different locations (n=14) across five zones: East (2), West (1), North (1), South (1), and Central (2) during June 2023. Staphylococcus aureus, Bacillus cereus, Escherichia coli, and Salmonella spp. were isolated and identified. For the microbial screening, bacterial enumeration, colony morphology, Gram's reaction, and biochemical characterization were performed. Amplification of nuc (S. aureus), nheA (B. cereus), phoA (E. coli), and 16S rRNA (Salmonella spp.) genes were carried out via Polymerase Chain Reaction assay.
Results: Total Viable Count (TVC) ranged from 3.93 to 6.08 log Colony Forming Units (CFU)/g while the Yeast and Mold Counts ranged from 2.30 to 4.28 log CFU/g. Using the conventional culture technique, the prevalence of S. aureus, B. cereus, and E. coli were found to be 3/14, 2/14, and 3/14, respectively; whereas based on molecular characterization, the prevalence was 0/14, 2/14, and 3/14, respectively. Salmonella spp. was not detected in any of the samples.
Conclusion: The study indicates a potential health hazard for consumers due to microbial contamination of street vended Vada pav samples. Consequently, it is crucial to regulate and improve hygienic practices in street food vendors.
Effect of Herb Urtica dioica as Feed Additive on Growth Performance, Serum Biochemical, Immune Response and Oxidative Parameters of Broilers
Authors: Mehboob Subata , Ganai Abdul Majeed , Sheikh G.G. , Beigh Y.A. , Nissa Shaista S. , Shubeena Sheikh 
Published: February 2025

Background: Considering the increasingly high cost of poultry feed and the economic aspects of poultry rearing, search for organic feed supplements for optimal growth performance along with maintaining the health status of poultry has emerged as a challenge for animal nutritionists all over the world. Over the years, medicinal herbs have fascinated a lot of consideration for their important role as alternatives to antibiotic growth promoters in animals. These compounds display some important pharmacological and growth promoting effects in animals. With this background, exploratory research was designed to study the effects of a locally available medicinal herb, Urtica dioica at different levels on the performance, serum biochemical, immune response and oxidative parameters of broilers. Methods: A total of 120-day old commercial broiler chicks were purchased; randomly distributed into four treatment groups. The groups were distributed as; group T1-control offered basal diet, groups T2, T3, T4 offered basal diet supplemented with Urtica dioica leaf powder @ 1, 1.5 and 2% respectively on dry matter basis. A growth trial of five weeks followed by a metabolic trial of seven days was conducted at the end of the experiment. The economics for broiler production was also calculated. In addition to this different biochemical, immune and oxidative parameter were also analyzed at the end of the experiment following standard procedures. Result: Significant improvements in various production parameters viz. body weight, FCR, digestibility of DM, CP were observed in birds fed nettle as feed additive in comparison to control, however non-significant changes in the values of feed intake, digestibility of CF, EE and NFE among treatment groups was also recorded. On calculating the economics, a lower production cost per kg live weight gain and a higher profit/bird was calculated for treatment groups fed nettle as feed additive. Significant improvements in various biochemical, immune and oxidative parameters were also observed in birds of phytogenic supplemented groups in comparison to control.
Assessing the Challenges of India’s No-Employment Policy for International Students
Authors: Noori Mohammad Ozair , Mohammady Khanullah 
Published: February 2025

Abstract

International students often face significant financial challenges due to tuition fees, living expenses and restricted access to financial aid. This study examines the impact of financial stress on students' perceptions of the no-employment policy, perceived benefits of part-time work, and career development. Using Structural Equation Modelling (SEM) analysis on primary data, the study finds that higher financial stress is associated with negative perceptions of the employment restriction and a stronger belief in the benefits of part-time work. Moreover, these perceptions influence students’ views on career development, highlighting the broader implications of employment restrictions on international students financial and professional well-being. The findings suggest that policymakers should reconsider employment restrictions for foreign students, as allowing part-time work could provide crucial financial support while enhancing career development opportunities.
A novel mechanism of the cachexia-promoting action of chemotherapy drugs fluorouracil and cisplatin
Authors: Lima Edson , Zhang Guohua , Zhang Zicheng , Gao Song , Wu Hongyu , Flores Rene , Yousif Omar , Li Min , Rodney George , Li Yi-Ping 
Published: February 2025

Abstract

Chemotherapy often contributes to cachexia, a lethal comorbidity of cancer characterized by
muscle wasting, resulting in poor therapeutic outcomes. Previous studies have shown that
frequently prescribed chemotherapy medications fluorouracil and cisplatin are toxic to skeletal
muscle directly, particularly at supratherapeutic doses without causing muscle catabolism. Here,
we show that therapeutic doses of fluorouracil and cisplatin, indirectly stimulate muscle catabolism
to increase muscle wasting by potentiating the cachexia-inducing capacity of cancer. At therapeutic
doses that effectively reduce tumor volume, fluorouracil and cisplatin potentiate muscle wasting
in KPC tumor-bearing mice by stimulating KPC cell release of EVs enriched with Hsp70 and
Hsp90 that stimulate muscle catabolism. Fluorouracil and cisplatin stimulate EV release by
upregulating Rab27a/b via activating NF-κB. In contrast, non-cachectic cancer cells respond to the
drugs by releasing EVs not enriched with Hsp70/90. These data reveal a novel mechanism and
potential therapeutic strategies for the cachexia-promoting action of fluorouracil and cisplatin.
Life-cycle management of fetal short femur length caused by achondroplasia: A case report
Authors: Zhou Qing , Zhong huaxiang , Wu Qingsong , Luo Xu , Lu xueqin , Cong Wenjie 
Published: February 2025

Abstract

Achondroplasia (ACH) is the most common non-lethal skeletal dysplasia and can lead to short femur length (FL), which is uncommon in the pediatric setting. This case report describes a case of fetal short FL caused by ACH, which was detected by routine ultrasonography during the 26th week of gestation in a 24-year-old woman. Based on the theory of the Bowen family system, the study followed the fetus and her family for 2.5 years, observed and analyzed the growth and development of the fetus, and provided psychological support to the family. In cases like this, life-cycle management is crucial and beneficial to ensure the healthy development and growth of the fetus with short femur length in the long term.
Visual quality after implantation of trifocal intraocular lenses with different diopter values in the two eyes
Authors: Zeng Yanfeng , Ma Qiyao , Qu Yuancheng , Wang Dongqing , Zhou Xiaoli , Wang Xiaoqin 
Published: February 2025

Abstract

This retrospective, non-randomized, comparative study aimed to evaluate visual quality and patient satisfaction after implantation of trifocal intraocular lens (IOL) with different diopter values in the two eyes.It was conducted from September 2021 to June 2023 at Lixiang Eye Hospital of Soochow University. Patients were divided into two groups.There were 62 eyes (31 patients) with IOL diopter difference > 1.0D (degree) in the study group and 62 eyes (31 patients) with IOL diopter difference ≤ 1.0D in the control group. Far, intermediate, and near vison, modulation transfer function (MTF), Strehl ratio (SR), higher-order aberrations, pupil shift during day and night, tertiary visual function, subjective visual quality in both groups were comparatively assessed.There were no statistically significant differences in uncorrected distance visual acuity (UDVA) and uncorrected intermediate visual (UIVA) for both eyes and the right eyes between the two groups. There were also no statistically significant differences in MTF, SR, simultaneous vision, fusion vision, coma, spherical aberration, VF-14-CN scores ,UDVA, UIVA and uncorrected near visual acuity (UNVA) for the left eyes between the two groups. UNVA levels of both eyes and the right eyes, higher-order, trefoil aberrations and glare were better in the control group than in the study group. Stereopsis was improved in the control group versus the study group. Night glare correlated with IOL diopter difference. The spectacle independence rate reached 100% in both groups.The study group had corrected anisometropia in both eyes, but stereopsis and near vision were inferior in these patients compared with the control group.
Perception and Confidence Levels of Dental Students and Newly Graduate Dentists during Prosthodontic Procedures
Authors: Almohefer Sami A. , Alkattan Rana K. , Aldakhayel Ghadah D. , Madfa Ahmed A. 
Published: February 2025

Background
Assessing students' perception of their dental school experience is a vital measure of the success and progress of dental education. Hence, the primary objectives of this research were to assess and examine the self-confidence levels of dental students and trainees at the University of Hail, Saudi Arabia, during prosthodontic procedures and to gauge their views on the quality of prosthodontic training.

Methods
Seventy-nine senior students and 39 new interns at the University of Hail, Saudi Arabia, were given surveys while keeping their identities anonymous. The participants were asked to evaluate their confidence level by using a Likert scale ranging from 1 to 5. The Mann-Whitney U test and chi-squared test were used to evaluate the statistical significance between the compared groups.

Results
49.2% of participants expressed contentment with the number of teeth identified for treatment. 89.8% of participants stated that increased practical experience would enhance their confidence in the field of prosthodontics. Approximately 49.5% of the participants surveyed stated they plan to pursue a specialized area in the coming years. Roughly 49.5% of the participants believed that their prosthodontic practice was at a moderate level. In general, this study's findings suggest that there were no significant differences between males and females (p > 0.05), except for rubber dam placement, follow-up appointment, and impression taking, where males exhibited greater confidence than females (p < 0.05). There were no significant differences between both groups in the treatment of different teeth (p > 0.05). Additionally, there were no significant differences (p > 0.05) in self-confidence levels for handling different indications for prosthodontic treatment.

Conclusion
The level of confidence during prosthodontic therapy in this study is regarded as neutral. Compared to the female and senior students, the male interns and students reported higher confidence.