bluuebunny/crossref_metadata_2025_split huggingface dataset:
An analysis of population using Multiple Linear Regression Analysis
Authors: Perdana Adityo Cakra , Rachman Rais , Palinggi Monika Datu Mirring 
Published: February 2021

Abstract
Makassar is one of the metropolitan cities located in South Sulawesi Province, the rapid progress of Makassar city makes Makassar as the destination of Eastern Indonesia as a center of education, health, job search and so on. Of course, this led to the emergence of new activity centers or new settlements that led to the rise of travel, resulting in a decrease in the level of road services. The purpose of this study is to analyze the trip generation of residents in the Puri Yuhana Permai housing and Bukit Khatulistiwa housing estates by using variables of the number of family members, the number of family members working, the number of families attending school/college, income, motorcycle ownership and private car ownership. Use the multiple linear regression method SPSS 25.0. The results of the research on each housing estate show that the variables that have a significant effect on the rise of the population journey on the housing of Puri Yuhana Permai and Bukit Khatulistiwa are the number of working (X5) and the number of who attend school (X6). This can be seen in the model of multiple linear regression equations namely Y = 0.202 + 0.570 X5 + 0.501X6 for Puri Yuhana Permai housing. Y = 0.182 + 0.378 X5 + 0.249X6 for Bukit Khatulistiwa housing
Time series modeling by using exponential smoothing technique for river flow discharge forecasting (case study: Cabenge, Walanae, and Cenranae rivers system)
Authors: Lukman Melly , Tanan Benyamin 
Published: February 2021

Abstract
The exponential smoothing technique is a time series modelling technique that can be used for forecasting. This technique is very important for use in hydrology to determine trends and predict future river flow conditions. In this study, 4 Exponential Smoothing Techniques were analyzed, namely Single Exponential Smoothing, Double Exponential Smoothing, Double Exponential Smoothing (Winters), and ARIMA to predict the flow of the Cabenge river on SWS Walanae - Cenranae. From the results of the study of the four Exponential Smoothing Techniques, Triple Exponential Smoothing (Winters) Of the 4 ES Techniques analyzed in this study, Triple Exponential Smoothing (TES) provides a more accurate forecasting value than Single Exponential Smoothing (SES), Exponential Smoothing Dual Smoothing (DES), and the Autoregressive Difference Moving Average (ARIMA). Triple Exponential Smoothing (TES) has smaller error values for MAPE, MAD, and MSD than SES and DES, and the comparison of forecasting discharge with measured discharge values shows a KN value of 93%. To predict the flow of the Cabenge river in SWS Walanae - Cenranae it is recommended to use the Triple Exponential Smoothing (Winters) Technique.
Electric bicycles with solar panels
Authors: Patoding Hestikah Eirene , Palebangan Reynold , Silolongan Maryanto D. 
Published: February 2021

Abstract
Solar energy is energy in the form of rays and heat from the sun. This energy can be harnessed by using a series of technologies such as solar panels. Solar panels are devices that consist of solar cells that convert light into electrical energy. The use of solar panels for battery charging on electric bicycles is the topic of this research. The process of developing an electric bicycle with solar power consists of several stages, starting from the preparation of the bicycle, the development design, the manufacture of the solar panel frame and holder, to the assembly and testing process. The result of this research is an electric bicycle uses a 24V, 12Ah battery with a charging time of 9 hours 33 minutes, using a 250 Watt DC motor. The maximum speed of an electric bicycle with solar panels is as expected, which is 20 km/hour with a distance of 16 km and a load of 89 kg. Mileage and travel time are affected by the weight of the rider.
Effect of variations in the composition of additives on the performance of petung bamboo charcoal briquettes
Authors: Suluh Sallolo , Bontong Yafet , Baan Anastasia , Labiran Roni , Patintingan Mersilina L. , Silka  
Published: February 2021

Abstract
The use of petung bamboo as a raw material for making charcoal briquettes will reduce dependence on fossil fuel energy which is already depleting. The abundant condition of petung bamboo waste in Toraja comes from the rest of the party activities of tuka signs and solo signs that are useful for making houses / loud places for relatives and guests to sit. This research was conducted by making charcoal briquettes from petung bamboo waste by varying the composition of the sago adhesive and clay as an alternative energy source. The purpose of this research is to determine the optimal thermal efficiency. The method to be used is an experimental method using petung bamboo waste as an alternative fuel on the stove with a water boiling process. The results showed that B2 briquettes (a mixture of 175 grams of petung bamboo charcoal and 25 grams of clay reinforcement) were the most superior in terms of boiling 21 liters of water and produced a thermal efficiency of 70.39%.
The miRNA: a small but powerful RNA for COVID-19
Authors: Zhang Song , Amahong Kuerbannisha , Sun Xiuna , Lian Xichen , Liu Jin , Sun Huaicheng , Lou Yan , Zhu Feng , Qiu Yunqing 
Published: February 2021

AbstractCoronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a severe and rapidly evolving epidemic. Now, although a few drugs and vaccines have been proved for its treatment and prevention, little systematic comments are made to explain its susceptibility to humans. A few scattered studies used bioinformatics methods to explore the role of microRNA (miRNA) in COVID-19 infection. Combining these timely reports and previous studies about virus and miRNA, we comb through the available clues and seemingly make the perspective reasonable that the COVID-19 cleverly exploits the interplay between the small miRNA and other biomolecules to avoid being effectively recognized and attacked from host immune protection as well to deactivate functional genes that are crucial for immune system. In detail, SARS-CoV-2 can be regarded as a sponge to adsorb host immune-related miRNA, which forces host fall into dysfunction status of immune system. Besides, SARS-CoV-2 encodes its own miRNAs, which can enter host cell and are not perceived by the host’s immune system, subsequently targeting host function genes to cause illnesses. Therefore, this article presents a reasonable viewpoint that the miRNA-based interplays between the host and SARS-CoV-2 may be the primary cause that SARS-CoV-2 accesses and attacks the host cells.
RNA-SeQC 2: efficient RNA-seq quality control and quantification for large cohorts
Authors: Graubert Aaron , Aguet François , Ravi Arvind , Ardlie Kristin G , Getz Gad 
Published: February 2021

Abstract

Summary
Post-sequencing quality control is a crucial component of RNA sequencing (RNA-seq) data generation and analysis, as sample quality can be affected by sample storage, extraction and sequencing protocols. RNA-seq is increasingly applied to cohorts ranging from hundreds to tens of thousands of samples in size, but existing tools do not readily scale to these sizes, and were not designed for a wide range of sample types and qualities. Here, we describe RNA-SeQC 2, an efficient reimplementation of RNA-SeQC (DeLuca et al., 2012) that adds multiple metrics designed to characterize sample quality across a wide range of RNA-seq protocols.

Availability and implementation
The command-line tool, documentation and C++ source code are available at the GitHub repository https://github.com/getzlab/rnaseqc. Code and data for reproducing the figures in this paper are available at https://github.com/getzlab/rnaseqc2-paper.

Supplementary information
Supplementary data are available at Bioinformatics online.
Development and Validation of Stability-indicating RP-HPLC Method for Estimation of Pranlukast Hydrate in its Laboratory Mixture
Authors: Kalyankar Gajanan G , Desai Prakruti N , Prajapati Pintu B , Lodha Sandesh R , Joshi Shrikant V , Bodiwala Kunjan B , Mishra Ashish A , Shah Shailesh A 
Published: February 2021

Abstract
Pranlukast hydrate is an anti-asthmatic drug and used in the treatment of acute asthma. Stability-indicating RP-HPLC method for pranlukast hydrate has been developed and validated. The reverse phase high performance liquid chromatographic method was developed using Shimadzu Column: Kromosil 100 C18 (150 mm × 4.6 mm × 5 μm) and mobile phase Acetonitrile: 0.1% Glacial acetic acid (85: 15% v/v). Eluent was monitored with UV-detector at 262 nm with a flow rate of 0.5 mL/min, temperature maintained at 30°C. Stress testing was carried out in acidic, alkaline, oxidative, photolytic and dry heat degradation conditions. The method was validated as per the International Conference for Harmonization guidelines and includes specificity, accuracy, precision, linearity and limit of quantitation and detection parameters. A relative standard deviation &lt;2% indicates the developed method was precise. The accuracy of the method was represented by recovery studies ranging between 99.41 and 99.72%. In acid, alkaline, oxidative stress conditions, pranlukast hydrate degrades significantly and in photolytic, dry heat, hydrolytic conditions remain stable. This proposed method is suitable for the analysis of pranlukast hydrate in its laboratory mixture.
Assessment of ICESat-2 for the recovery of ocean topography
Authors: Yu Yao , Sandwell David T , Gille Sarah T , Villas Bôas Ana Beatriz 
Published: February 2021

SUMMARYThe Ice, Cloud and land Elevation Satellite 2 (ICESat-2) laser altimetry mission, launched in September 2018, uses six parallel lidar tracks with very fine along-track resolution (15 m) to measure the topography of ice, land and ocean surfaces. Here we assess the ability of ICESat-2 ocean data to recover oceanographic signals ranging from surface gravity waves to the marine geoid. We focus on a region in the tropical Pacific and study photon height data in both the wavenumber and space domain. Results show that an ICESat-2 single track can recover the marine geoid at wavelengths &gt;20 km which is similar to the best radar altimeter data. The wavelength and propagation direction of surface gravity waves are sometimes well resolved by using a combination of the strong and weak beams, which are separated by 90 m. We find higher than expected power in the 3–20 km wavelength band where geoid and ocean signals should be small. This artificial power is caused by the projection of 2-D surface waves with ∼300 m wavelengths into longer wavelengths (5–10 km) because of the 1-D sampling along the narrow ICESat-2 profile. Thus ICESat-2 will not provide major improvements to the geoid recovery in most of the ocean.
A proposed framework for reporting mass mortality (wreck) events of seabirds
Authors: Glencross Jacqueline S , Lavers Jennifer L , Woehler Eric J 
Published: February 2021

Abstract
There is an absence of quantitative criteria and definitions for unusual or anomalous mortality events involving birds, often referred to as “wrecks”. These events most commonly involve seabirds, although terrestrial bird wrecks have also been documented. Typically, the peer-reviewed literature investigating wreck events lacks the details necessary to further our understanding of the circumstances and potential causes of these events. This study reviewed the peer-reviewed literature for wrecks involving Ardenna seabirds (shearwaters), and included grey literature and data collected by citizen science (community) groups. Our results showed a significant time-lag between wreck events and when the data was published in the peer-reviewed literature, which did not occur in the grey literature. Both the grey and peer-reviewed literature were often skewed towards reporting larger wreck events, with only the citizen science dataset capturing smaller wrecks. We outline a proposed framework for reporting mortality events, including the use of quantitative categories to document the numbers of birds involved and taxon-specific thresholds. In doing so, we aim to establish a framework to aid in the quantitative reporting and analyses of future seabird wrecks.
Pragmatic comparative effectiveness study of multimodal fascia iliaca nerve block and continuous lumbar epidural-based protocols for periacetabular osteotomy
Authors: Albertz Megan , Whitlock Patrick , Yang Fang , Ding Lili , Uchtman Molly , Mecoli Marc , Olbrecht Vanessa , Moore David , McCarthy James , Chidambaran Vidya 
Published: February 2021

AbstractPerioperative pain management protocols have a significant impact on early surgical outcomes and recovery. We hypothesized that multimodal protocol including fascia iliaca compartment nerve block (MM-FICNB) would decrease the length of hospital stay (LOS) by facilitating earlier mobilization, without compromising analgesia, compared to a traditional lumbar epidural-based protocol (EP). Demographics/comorbidities, surgical/block characteristics and perioperative pain/mobilization data were collected from a prospectively recruited MM-FICNB group (N = 16) and a retrospective EP cohort (N = 16) who underwent PAO using similar surgical techniques, physical therapy/discharge criteria. Association of MM-FICNB group with LOS (primary outcome), postoperative pain, postoperative opioid requirements in morphine equivalent rates (MER) (mcg/kg/h) and time to complete physical therapy were tested using multivariable and survival regression. Patient and surgical characteristics were similar between groups. Median time for FICNB performance was significantly less than epidural (6 versus 15 min; P &lt; 0.001). LOS was significantly decreased in the MM-FICNB group (2.88 ± 0.72 days) compared to the EP group (4.38 ± 1.02 days); P &lt; 0.001. MM-FICNB group had significantly lower MER on POD1 (P = 0.006) and POD2 (P &lt; 0.001), with similar pain scores on all POD. MM-FICNB group was associated with decreased LOS and earlier mobilization (P &lt; 0.001) by covariate-adjusted multivariate regression. Cox proportional hazard regression model showed MM-FICNB subjects had 63 (95% CI 7–571, P &lt; 0.001) times the chance of completing physical therapy goals, compared to EP. Compared to EP, MM-FICNB protocol allowed earlier mobilization and decreased post-surgical hospitalization by 1.5 days, without compromising analgesia, with important implications for value-based healthcare and cost-effectiveness.
A rare case of pulmonary embolus after arthroscopic meniscus surgery
Authors: Hu Janie , Cox MaKayla , Yang Alexander 
Published: February 2021

Abstract
Although there is consensus that thromboprophylaxis is necessary for major orthopedic surgeries such a joint replacement, there is no widespread consensus on the need for thromboprophylaxis for minor arthroscopic surgery. Here, we present a case of deep vein thrombosis (DVT) and pulmonary embolism (PE) after a common arthroscopic meniscectomy in a healthy 20-year-old female collegiate athlete. The patient had no risk factors except for prior use of combined oral contraceptive pills (COCPs). Twenty hours after an uncomplicated right knee meniscectomy, patient presented to ED with right calf pain and cramping, and DVT was confirmed using ultrasound. One week later, patient presented again to ED with dyspnea and chest pain. PE was diagnosed on CT angiography. Despite the rarity of thromboembolic complications in minor arthroscopy surgery, the broadened use of thromboprophylaxis in patients with even few risk factors could prevent thromboembolic complications from occurring.
Using the Socio-ecological Model to Explore Facilitators and Deterrents of Tobacco Use Among Airmen in Technical Training
Authors: Porter Kathleen J , Krukowski Rebecca A , Bonilla Gloribel , McKenna Lisa , Talcott Gerald W , Little Melissa A 
Published: February 2021

ABSTRACT

Introduction
Military personnel have some of the highest rates of tobacco use in the USA. Within the Air Force, a common point of Airmen’s (re-)initiation of tobacco use is during technical training once the tobacco ban has been lifted. Unfortunately, little is known about what factors facilitate and deter tobacco use during technical training. The socio-ecological model, which emphasizes multiple levels of influence on behavior (e.g., personal, intrapersonal, and environmental), provides a strong and comprehensive basis for which to explore factors that may impact tobacco use during technical training.

Materials and Methods
Twenty-two focus groups were conducted among Airmen (n = 10), Military Training Leaders (MTLs, n = 7), and Technical Training Instructors (TTIs, n = 5). Semi-structured focus group protocols were developed based on the socio-ecological model and included questions intended to elicit factors that facilitated and deterred tobacco use during technical training. Focus groups were transcribed and then coded using a hybrid deductive-inductive process.

Results
At the personal level, five factors were identified that influenced tobacco use: choice, fit with lifestyle, associations with the tobacco experience, association with military job outcomes, and association with health outcomes. Three interpersonal level factors were identified: peer influence, leadership influence, and normative beliefs. There were two influential environmental level factors: pricing and promotion and access to tobacco. Except for normative beliefs, all personal, interpersonal, and environmental-level factors were discussed as having aspects that could either facilitate or deter tobacco use. Normative beliefs, an interpersonal-level factor, were only discussed as a facilitator of tobacco use.

Conclusions
Taken together, study findings can be used to enhance the effectiveness of tobacco prevention and cessation programs for Air Force Technical Trainees. Specific strategies to support the reduction of tobacco use among Airmen are presented.
Stellar-mass black holes in young massive and open stellar clusters – V. comparisons with LIGO-Virgo merger rate densities
Authors: Banerjee Sambaran 
Published: February 2021

ABSTRACT
I study the contribution of young massive star clusters (YMCs) and open star clusters (OCs) to the present day, intrinsic merger rate density of dynamically assembled binary black holes (BBHs). The BBH merger event rate is estimated based on a set of state-of-the-art evolutionary models of star clusters, as presented in Banerjee (2021). The merger-event rates are obtained by constructing a cluster population of the Universe, out of the models, taking into account mass distribution of clusters and cosmic star formation and enrichment histories, as per observations. The model BBH merger rate density ranges from a pessimistic to a reference value of 0.5−37.9 yr−1 Gpc−3, for a LIGO-Virgo-like detector horizon. The reference rate well accommodates the BBH merger rate densities estimated from GWTC-1 and GWTC-2 merger-event catalogues. The computed models also yield differential BBH merger rate densities that agree reasonably with those from GWTC-1 and, as well, with the much more constrained ones from GWTC-2. These results suggest that dynamical interactions in YMCs and OCs can, in principle, alone explain the BBH merger rate density and its dependence on the merging-binary properties, as inferred from to-date gravitational-wave (GW) events. The cosmic merger rate density evolution also agrees with GWTC-2. The models predict a rate of ≈5 yr−1 Gpc−3 for eccentric LIGO-Virgo mergers from YMCs and OCs. The improving constraints on BBH merger rate density with mounting GW events will help constraining scenarios of star cluster formation across cosmic time and as well the relative contributions of the various compact binary merger channels.
Neuroform Atlas Stent for Treatment of Middle Cerebral Artery Aneurysms: 1-Year Outcomes From Neuroform Atlas Stent Pivotal Trial
Authors: Hanel Ricardo A , Yoon Nam , Sauvageau Eric , Aghaebrahim Amin , Lin Eugene , Jadhav Ashutosh P , Jovin Tudor G , Khaldi Ahmad , Gupta Rishi G , Johnson Andrew , Frei Donald , Loy David , Malek Adel , Toth Gabor , Siddiqui Adnan , Reavey-Cantwell John , Thomas Ajith , Hetts Steven W , Jankowitz Brian T , Zaidat Osama O 
Published: February 2021

Abstract

BACKGROUND
Heterogeneous effect of endovascular aneurysm therapy has been observed across different anatomic locations. There is a paucity of data for stent-assisted coiling of middle cerebral artery (MCA) aneurysms.

OBJECTIVE
To present the results of the MCA aneurysm group from the Neuroform Atlas (Stryker Neurovascular) investigational device exemption (IDE) trial.

METHODS
The Atlas IDE trial is a prospective, multicenter, single-arm, open-label study of wide-neck aneurysms (neck ≥ 4 mm or dome-to-neck ratio < 2) in the anterior circulation treated with the Neuroform Atlas Stent and approved coils. Follow-up was obtained immediately postprocedure and 2, 6, and 12 mo postoperatively. We herein describe safety and efficacy outcomes, and functional independence of the subjects with aneurysms from all segments of MCA.

RESULTS
A total of 35 patients were included (27 MCA bifurcation, 5 M1, 3 M2). The mean aneurysm size was 6.0 ± 1.8 mm, and the mean neck was 4.4 ± 1.2 mm. Technical procedural success was achieved in all patients. A total of 26 patients had follow-up digital subtraction angiography available at 12 mo, with 80.8% (21/26) having complete aneurysm occlusion. Twelve-month safety data were collected for 91.4% (32/35), 8.5% (3/35) had primary safety endpoint, all 3 major ischemic strokes. Mortality occurred in 2 patients beyond 30 d unrelated to procedure (1 gallbladder cancer and 1 fentanyl intoxication). At 1 yr, modified Rankin Score was 0 to 2 in 84.4% (27/32), 3 in 9.4%, and 3 patients were missing. Approximately 5.7% (2/35) of patients were retreated at 12 mo.

CONCLUSION
Stent-assisted coiling with the Neuroform Atlas Stent is a viable alternative to clipping for selected MCA aneurysms. Complete aneurysm occlusion rates have improved compared to historical data. Proper case selection can lead to acceptable endovascular results.