bluuebunny/crossref_metadata_2025_split huggingface dataset:
Revisión bibliográfica sobre la memoria histórica de pandemias anteriores en revisiones de enfermería sobre COVID-19: una realidad secularmente documentada
Authors: Leon Molina Joaquin , Hellin Gil M Fuensanta , Abad Corpa Eva 
Published: August 2021

Introducción: Las revisiones sobre COVID-19 deberían reflejar antecedentes históricos de anteriores pandemias. Objetivo: Nos planteamos mapear el contenido de revisiones recientes, en el área de enfermería sobre COVID-19, para comprobar si se hace alusión a crisis sanitarias por epidemias y enfermedades infecciosas. Metodología. Revisión narrativa descriptiva. Se consultaron la Web de la Ciencia, PubMed y Lilacs para identificar las revisiones; se consultó el contenido de los documentos para detectar la presencia de descriptores y términos relativos a las pandemias anteriores al siglo XXI de la humanidad, atendiendo a los criterios de inclusión y objetivos del estudio. Resultados: Sólo en 11 documentos de los 192 identificados se localizaron reseñas pertinentes. Conclusiones: Pueden existir reticencias a la hora de utilizar documentación publicada hace más de un siglo; sin embargo, sería aconsejable no perder la memoria histórica de crisis pandémicas que ha padecido la humanidad durante milenios.
Introduction: Reviews for COVID-19 should reflect historical antecedents from previous pandemics.Objective: We plan to map the content of recent reviews in the nursing area on COVID-19 to see if it refers to health crises due to epidemics and infectious diseases.Methodology: Descriptive narrative review. The Science Web, PubMed and Lilacs were consulted to identify the reviews; The content of the documents was consulted to detect the presence of descriptors and terms related to pandemics prior to the 21st century of humanity, taking into account the inclusion criteria and objectives of the study.Results: Relevant reviews were found only in 11 documents of the 192 identified.Conclusions: There may be reluctance to use documentation published more than a century ago; However, it would be advisable not to lose the historical memory of pandemic crises that humanity has suffered for millennia
Can India Go in for Pre- School / Pre- Verbal Eye Screening Now with Red Reflex? - A Feasibility Study
Authors: Gupta Himika , Singh Ravikant , Ernam Sunila Sanjeev 
Published: August 2021

Aims: To study the feasibility and challenges for early vision screening of the 0-6 yr preverbal/ preschool children in both urban and rural settings of India using the simple Red Reflex test.
Study Design:Operational research.
Place and Duration of Study: Four settings (two urban and two rural) were designed to target the 0-6year old children. Model I .Pre School (Urban slum Population), Model II. Health Centre (Urban Hospital), Model III. Immunization OPD of Municipal Hospital (Rural hospital) Model IV. Anganwadi Centre (Rural Population) was designed and conducted July 2017 –Dec 2017 (6 months).
Methodology: All models were conducted as single day vision screening camps except Model III which was an opportunistic screening for a period of 3 months (July – Sept 2017). Vision screening was done using Red Reflex test and follow up was done for three months. Data was analyzed on MS Excel and expressed in proportions / percentages.
Results: Maximum children (155) were screened in Model I. Out of the 301 total children screened 33 (10.96%) had abnormal Red Reflex test. The yield was maximum 6 (17.14%) in Model III. Urban health centre Model I was the most time efficient model(average 0.74 minutes/child).
Conclusions: Single day screening of population based cohort is time efficient but opportunistic screening using universal immunization programme model had maximum yield.
Production environment and managerial techniques in explaining productivity growth in Brazilian beef cattle production
Authors: Martins Maristela M. , Spolador Humberto F. S. , Njuki Eric 
Published: August 2021

AbstractBrazil is a key player in the global beef markets having generated 15% of global production, and approximately 20% of world exports in 2018. Productivity improvements will be indispensable if the Brazilian beef sector wants to maintain its position as a key player in both the domestic and international markets. In light of the aforementioned, this study makes two key contributions to the agricultural productivity literature on Brazil. First, it estimates the production technology used in the Brazilian beef cattle sector using stochastic production frontier methods that account for exogenous factors that impact the production environment. Second, using the estimated coefficients as weights, it decomposes a total factor productivity (TFP) index that tracks various sources of productivity growth including: technical efficiency, technological change, scale efficiency, and environmental efficiency. By utilizing farm‐level data this study generates deeper insights into the dynamics driving beef cattle production at the most disaggregated level. Results indicate that TFP growth averaged 1.73% per annum and was primarily driven by scale efficiency, which increased at 1.39%. Meanwhile, technical efficiency declined at a rate of −0.03% per annum. [EconLit Citations: D24, O13, Q15].
PtSe2/Pt Heterointerface with Reduced Coordination for Boosted Hydrogen Evolution Reaction
Authors: Wang Zongpeng , Xiao Beibei , Lin Zhiping , Xu Yaping , Lin Yan , Meng Fanqi , Zhang Qinghua , Gu Lin , Fang Baizeng , Guo Shaojun , Zhong Wenwu 
Published: August 2021

AbstractPtSe2 is a typical noble metal dichalcogenide (NMD) that holds promising possibility for next‐generation electronics and photonics. However, when applied in hydrogen evolution reaction (HER), it exhibits sluggish kinetics due to the insufficient capability of absorbing active species. Here, we construct PtSe2/Pt heterointerface to boost the reaction dynamics of PtSe2, enabled by an in situ electrochemical method. It is found that Se vacancies are induced around the heterointerface, reducing the coordination environment. Correspondingly, the exposed Pt atoms at the very vicinity of Se vacancies are activated, with enhanced overlap with H 1s orbital. The adsorption of H. intermediate is thus strengthened, achieving near thermoneutral free energy change. Consequently, the as‐prepared PtSe2/Pt exhibits extraordinary HER activity even superior to Pt/C, with an overpotential of 42 mV at 10 mA cm−2 and a Tafel slope of 53 mV dec−1. This work raises attention on NMDs toward HER and provides insights for the rational construction of novel heterointerfaces.
Knockdown circ_0040414 inhibits inflammation, apoptosis and promotes the proliferation of cardiomyocytes via miR‐186‐5p/PTEN/AKT axis in chronic heart failure
Authors: Feng Yanling , Yan Biao , Cheng Hongji , Wu Jinlei , Chen Qinxiu , Duan Yuexing , Zhang Peng , Zheng Dong , Lin Guixiong , Zhuo Yufeng 
Published: August 2021

AbstractPrevious studies have shown that circ_0040414 is highly expressed in the blood of patients with heart failure (HF), which suggests that circ_0040414 is associated with heart failure (HF). However, the functional involvement of circ_0040414 in HF and its potential mechanism remains unclear. Consistent with previous studies, our study showed that the expression of circ_0040414 in the peripheral blood of patients with chronic heart failure (CHF) was significantly higher than that of healthy control, which indicated that circ_0040414 could be used as a diagnostic biomarker in patients with CHF. In cardiomyocytes, circ_0040414 increased the level of proapoptotic proteins Bax, cleaved‐caspase 3 and reduced the expression of antiapoptotic protein Bcl‐2. It also promoted inflammatory factors IL‐6, TNF‐α, and IL‐β, but inhibited cell proliferation. In terms of mechanism, circ_0040414 upregulated the expression of phosphatase and tensin homolog (PTEN) through sponging miR‐186‐5p to inhibit AKT signaling activity. Our study uncovered a novel role and the mechanism of circ_0040414 in controlling CHF, enriched the molecular regulatory network in CHF, and may provide a possible strategy for the treatment of CHF.
Sample Preparation for Detection of Different Bacterial Strains by Matrix‐Assisted Laser Desorption/Ionization Time‐of‐Flight (MALDI‐TOF) Mass Spectrometry
Authors: Chac Denise , Kordahi Melissa , Brettner Leandra , DePaolo R. William 
Published: August 2021

AbstractMatrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS) provides a fast and easy means to identify culturable microorganisms to the species level. The sample preparation of microbial colonies for MALDI‐TOF analysis requires a suitable protein extraction method. While standard MALDI‐TOF sample preparation methods are well suited for the identification of and the discrimination between microorganisms belonging to different species, they are not disruptive enough to allow the discrimination between different strains of the same microorganism. More disruptive protein extraction methods lead to better discrimination power because they allow a better breakdown of bacterial cell membrane and a more efficient extraction of conserved microbial proteins that are specific to each species and strain. Here we describe how to extract proteins from single microbial colonies using formic acid and acetonitrile to disrupt cells prior to placing them on a target plate for MALDI‐TOF MS analysis. Contrary to other sample preparation methods for MALDI‐TOF MS, this approach allows the discrimination between different strains of microorganisms of the same species. Our approach also provides the groundwork data for building algorithms that allow the detection of specific microbial strains of interest, with a great potential for diagnostic applications in clinical settings. © 2021 Wiley Periodicals LLC.Basic Protocol: Protein extraction and MALDI‐TOF bio‐typing of phenotypically distinct bacterial species
Changes in the demand for CSR activities and stakeholder engagement based on research conducted among public relations specialists in Poland, with consideration of the SARS‐COV‐2 pandemic
Authors: Tworzydło Dariusz , Gawroński Sławomir , Opolska‐Bielańska Agata , Lach Mateusz 
Published: August 2021

AbstractCare for the external and internal environment of the company, ethics and human resources, as well as the organizational culture, is a crucial element for the importance and competitive advantage of the company. It was especially noticeable during the SARS‐COV‐2 pandemic. Companies began to grapple with difficulties, which contributed to an increased interest in crisis management competencies. The pandemic has permanently changed the functioning of society and the image of many industries, including public relations. The analysis of changes in the demand of companies for CSR‐related activities after the pandemic becomes a valuable element of the direction of innovative research. Recognizing the interest, these aspects of the company were verified. The article uses data obtained in the course of the implementation of three independent research projects realized in Poland. The first study concerned crisis management from the perspective of a public relations agencies. The structures of the offer of public relations services (including CSR strategies) were examined. The responses of some public relations specialists regarding CSR and activities in this area after the COVID‐19 pandemic were extracted from the second research project. The last, third project involved specialists employed in PR agencies. The research area covered changes in the demand of companies for CSR‐related activities after the pandemic and the desired areas of training and personal development, with particular emphasis on CSR. The common denominator of all three projects is CSR campaigns and the way they are implemented by PR specialists.
What does it mean to be wild? Assessing human influence on the environments of nonhuman primate specimens in museum collections
Authors: Eller Andrea R. , Canington Stephanie L. , Saiyed Sana T. , Austin Rita M. , Hofman Courtney A. , Sholts Sabrina B. 
Published: August 2021

AbstractObjectivesNatural history collections are often thought to represent environments in a pristine natural state—free from human intervention—the so‐called “wild.” In this study, we aim to assess the level of human influence represented by natural history collections of wild‐collected primates over 120 years at the Smithsonian Institution's National Museum of Natural History (NMNH).Materials and MethodsOur sample consisted of 875 catarrhine primate specimens in NMNH collections, representing 13 genera collected in 39 countries from 1882 to 2004. Using archival and accession information we determined the approximate locations from which specimens were collected. We then plotted location coordinates onto publicly available anthrome maps created by Ellis et al. (Global Ecology and Biogeography, 2010, 19, 589), which delineate terrestrial biomes of human population density and land use worldwide since the 1700s.ResultsWe found that among primates collected from their native ranges, 92% were from an environment that had some level of human impact, suggesting that the majority of presumed wild‐collected primate specimens lived in an environment influenced by humans during their lifetimes.DiscussionThe degree to which human‐modified environments may have impacted the lives of primates currently held in museum collections has been historically ignored, implicating unforeseen consequences for collection‐based research. While unique effects related to commensalism with humans remain understudied, effects currently attributed to natural phenomena may, in fact, be related to anthropogenic pressures on unmanaged populations of primates.
Fatty acid profile and safety aspects of the edible oil prepared by artisans' at small‐scale agricultural companies
Authors: Bartkiene Elena , Bartkevics Vadims , Berzina Zane , Klementaviciute Jolita , Sidlauskiene Sonata , Isariene Ausra , Zeimiene Vaida , Lele Vita , Mozuriene Erika 
Published: August 2021

AbstractThe aim of this study was to analyze the fatty acid (FA) profiles and mycotoxin and polycyclic aromatic hydrocarbon (PAH) concentrations in sea buckthorn (SB1, SB2), flaxseed (FL3, FL4, FL5), hempseed (HE6, HE7, HE8), camelina (CA9, CA10), and mustard (MU11) edible oils, prepared by artisans’ by artisanal at small‐scale agricultural companies in Lithuania. The dominant FAs were palmitic and oleic acids in SB; palmitic, stearic, oleic, linoleic, and α‐linolenic acids in FL; palmitic, stearic, oleic, linoleic, and α‐linolenic acids in HE; palmitic, oleic, linoleic, α‐linolenic, eicosenoic, and erucic acids in CA; and oleic, linoleic, α‐linolenic, eicosenoic, and erucic acids in MU. In SB2 oil samples, T‐2 toxin and zearalenone concentrations higher than 1.0 µg/kg were found (1.7 and 3.0 µg/kg, respectively). In sample FL4, an ochratoxin A concentration higher than 1.0 µg/kg was established (1.2 µg/kg); also, in HE8 samples, 2.0 µg/kg of zearalenone was found. None of the tested edible oils exceeded the limits for PAH concentration. Finally, because of the special place of edible oils in the human diet, not only should their contamination with mycotoxins and PAHs be controlled but also their FA profile, as an important safety characteristic, must be taken into consideration to ensure higher safety standards.
Blacklight‐Induced Hydroxylation of Arylboronic Acids Leading to Hydroxyarenes Using Molecular Oxygen and Tetrabutylammonium Borohydride
Authors: Kawamoto Takuji , Ryu Ilhyong 
Published: August 2021

AbstractA new simple protocol for the conversion of arylboronic acids to hydroxyarenes was achieved using molecular oxygen in the presence of tetrabutylammonium borohydride under blacklight irradiation (360 nm). A radical chain mechanism in which a superoxide ion (O2−.) plays a key role is proposed.
Cortical thickness in clinical moyamoya disease: A magnetic resonance imaging study
Authors: Tompkins Grace , Levman Jacob , Ijner Prahar , Shiohama Tadashi , Takahashi Emi 
Published: August 2021

AbstractMoyamoya disease (MMD) is a progressive cerebrovascular disorder, with an unknown pathogenesis and aetiology. MMD is characterized by steno‐occlusive changes at the terminal portion of the internal carotid artery (ICA), which is accompanied by variable development of the basal collaterals, also known as moyamoya vessels. Patients with MMD show variable patterns of brain damage and may experience recurrent multiple transient ischaemic attacks, intracranial bleeding and cerebral infarction. In this study, we investigate the potential for structural T1 magnetic resonance imaging (MRI) to help characterize abnormal cortical development in MMD clinically, with an analysis of both average and variability of regional cortical thicknesses. This study also included a machine learning analysis to assess the predictive capacity of the cortical thickness abnormalities observed in this research. This study included 993 MRI examinations from neurotypical controls and 269 MRI examinations from MMD patients. Results demonstrate abnormal cortical presentation of the insula, caudate, postcentral, precuneus and cingulate regions, in agreement with previous literature cortical thickness findings as well as alternative methods such as functional MRI (fMRI) and digital angiography. To the best of our knowledge, this is the first manuscript to report cortical thickness abnormalities in the middle temporal visual area in MMD and the first study to report on cortical thickness variability abnormalities in MMD.
Severe cytomegalovirus disease with encephalitis after CAR‐T cell therapy: A rare but potentially fatal complication
Authors: Cousin Elie , Belicard Félicie , Michel Laure , Pronier Charlotte , Lassalle Nicolas , Lamy Thierry , Houot Roch , Lhomme Faustine 
Published: August 2021

AbstractCytomegalovirus (CMV) is a ubiquitous herpes virus that develops lifelong latency following primary infection and can be reactivated following immune suppression. CMV encephalopathy has been described in few reports after hematopoietic stem cell transplantation and in patients with acquired immunodeficiency syndrome. To the best of our knowledge, CMV encephalopathy following CAR‐T cells infusion had not been previously reported. Initial CMV viral load and monitoring are crucial in patients with CAR‐T cells to allow early intervention with aggressive antiviral treatment without delay if needed.
Novel multinutrient human milk‐based human milk fortifier promotes growth and tolerance in premature infants
Authors: Gates Amy , Thompson Amy B. , Marin Terri , Waller Jennifer L. , Patel Jenny , Stansfield Brian K. 
Published: August 2021

AbstractBackgroundThe objective of this study was to determine whether human milk supplemented with a novel human milk–based human milk fortifier (Novel HMF), compared with a bovine milk–based HMF (Bovine HMF), supports preterm infant growth through 36 weeks’ postmenstrual age (PMA).MethodsThis single‐center, prospective trial compared growth and nutrition outcomes of preterm infants provided a human milk–based diet (mother's own milk or donor milk) supplemented with a Novel HMF with historic controls provided Bovine HMF. Preterm infants with an estimated gestational age (EGA) between 23 and 33 weeks’ PMA and birth weight between 750 and 1800 g were eligible for study inclusion. Weight, length, and head circumference (HC) were monitored weekly. The occurrence of late‐onset sepsis, nil per os (NPO) days, necrotizing enterocolitis, metabolic acidosis, and serious adverse events were monitored.ResultsBirth weight, length, HC, and EGA were similar between the Novel HMF (n = 37) and Bovine HMF (n = 49) groups. The days to regain birth weight was shorter in the Novel HMF group (9.4 ± 4.0 vs 11.4 ± 4.8, P = .0343), with similar weight gain (g/day) from birth to 36 weeks’ PMA. Adjusted weight growth velocity (g/kg/day) was significantly higher in the Novel HMF group at 14 and 21 days but similar at 36 weeks’ PMA. The Novel HMF group experienced fewer NPO days with a similar total number of feeding days.ConclusionsA novel, multinutrient, human milk–based HMF is well tolerated and meets the nutrition needs of preterm infants.
Climate, fire and vegetation history from subtropical North Stradbroke Island (Minjerribah), eastern Australia, during the last three interglacials
Authors: Kemp Christopher , Tibby John , Barr Cameron , Arnold Lee 
Published: August 2021

ABSTRACTRecords of Australian palaeoclimate beyond the last glacial cycle are rare, limiting detailed analysis of long‐term climate trends and associated ecosystem responses. This study analyses a discontinuous pollen and charcoal record from Fern Gully Lagoon, North Stradbroke Island (Minjerribah), subtropical Queensland, Australia, which covers much of the last ~210 ,000 years. Climate variation is inferred from changes in vegetation, while analysis of micro‐ and macrocharcoal is used to infer fire activity. Pollen assemblages consist of ~40% rainforest taxa during marine isotope stage (MIS) 7a–c and early MIS 5. These are inferred to result from high rainfall in the Australian subtropics, which was also evident in north‐east and central Australia. Human impact from 21 ,000 years ago likely supressed post‐MIS 2 rainforest expansion to some extent. However, the increased Holocene abundance of herbs and grasses and reduced representation of aquatic taxa suggest that the Holocene was relatively dry when compared with early MIS 5 and MIS 7a–c. Similar MIS 5 and early MIS 7a–c climates, in contrast to a notably drier Holocene, suggest that the progressive interglacial drying trend most strongly recorded in central Australia was not a major feature of subtropical eastern Australian climates.
Tebipenem pivoxil hydrobromide—No PICC, no problem!
Authors: Sodhi Varun , Kronsberg Kelli A. , Clark Mickayla , Cho Jonathan C. 
Published: August 2021

AbstractTebipenem pivoxil hydrobromide is a novel orally bioavailable prodrug of tebipenem, a carbapenem antimicrobial, that binds to penicillin‐binding proteins, inhibiting the synthesis of the bacterial cell wall. This results in weakening of peptidoglycan, leading to lysis of bacterial cells. Tebipenem displays a broad spectrum of activity against anaerobic, gram‐positive, and gram‐negative pathogens, including extended‐spectrum β‐lactamase producing Enterobacterales. In a large phase 3 clinical trial (ADAPT‐PO), oral tebipenem pivoxil hydrobromide 600 mg every 8 h was shown to be non‐inferior to intravenous ertapenem 1 g every 24 h. Overall response at test of cure was 58.8% [264/449] in the tebipenem pivoxil hydrobromide group compared to 61.6% [258/419] in the ertapenem group for the treatment of complicated urinary tract infections, including acute pyelonephritis. At the test of cure, clinical cure rates were 93.1% and 93.6% and microbiological eradication was 59.5% and 63.5% with tebipenem pivoxil hydrobromide and ertapenem, respectively. The most common adverse reactions associated with tebipenem pivoxil hydrobromide are diarrhea, headache, and nausea. As with other carbapenems, tebipenem pivoxil hydrobromide is expected to have the potential to decrease the seizure threshold and will likely require renal dosage adjustment for patients with altered renal function due to high renal clearance. If approved in the United States, tebipenem pivoxil hydrobromide can serve as a potential oral antimicrobial option to decrease hospital length of stay and prevent hospital admissions due to resistant pathogens.