bluuebunny/crossref_metadata_2025_split huggingface dataset:
PSV-10 The effects of maternal programming on postnatal growth and inflammation in neonatal dairy bull calves
Authors: Barney Amanda , Lally Jordan , Gately Rachael , Hoffman Maria L 
Published: October 2021

Abstract
Neonatal dairy calves are highly susceptible to respiratory and digestive diseases. A mechanism that could be predisposing calves to disease is maternal programming. We hypothesized that high milk production and/or mastitis infection during gestation will 1) affect postnatal growth and development 2) cause increased inflammation in neonatal dairy bull calves. Calves (n = 45) were selected from dams classified has high producers (HI; Top 25% for herd M305; n = 7), high producers with high SCC (HIMAST; SCC test during pregnancy over 200,000 cells/mL; n = 15), moderate producers (MOD; lower 60% for herd M305; n = 17) or moderate producers with high SCC (MODMAST; n = 6). Calves were transported to the University of Rhode Island at 24 hrs of age. Body weights and body measurements (crown rump length (CRL), skull length (SL), skull width (SW), Girth, Height) were collected at 24 hrs (Initial) and at weaning (8 weeks). C-reactive protein (Abclonal, Woburn, MA) and Malondialdehyde (Abcam, Cambridge, MA) analyses were performed on plasma samples collected 72 hrs post travel. Data were analyzed in SAS using repeated measures (BW and growth measurements) and proc mixed (inflammatory biomarkers). As expected, an effect of time was observed on calf BW, CRL, SL, SW, Girth and Height (P ≤ 0.01). However, no difference in calf BW, CRL, SL, SW, Girth and Height were observed between groups (P&gt;0.05). No effect of dam milk production and/or SCC during gestation was observed on CRP or MDA concentrations at 72 hrs post travel (P ≥ 0.17). In conclusion, high maternal milk production and/or mastitis infection during gestation does not affect calf BW and body measurements when analyzed overtime. Correlation analyses will be performed to better understand the relationship between maternal programming and calf growth. Additional inflammatory biomarkers are also going to be evaluated.
PSV-1 Injectable trace mineral supplementation on grazing beef cows: Effect on subsequent offspring birth weight and weaning weight
Authors: Pancini Stefania , Currin John , Stewart Jamie L , Clark Sherrie , Redifer Tracey , Wege Dias Nicholas W , Timlin Claire L , Sales Alvaro , Mercadante Vitor R G 
Published: October 2021

Abstract
This study evaluated the effect of an injectable multi-mineral complex supplementation on grazing beef cows on subsequent offspring birth weight (BW) and adjusted weaning weight (AWW). Experiment 1 included 1,128 Angus crossbred multiparous suckled cows, from 9 locations in Virginia, that were randomly assigned to one of two treatments: 1) One dose of an injectable trace mineral (6 mL; Multimin® 90, Multimin USA, Ft. Collins, CO) at 71.4±16.8 d of lactation (n = 560); or 2) a negative control with no trace mineral injection (n = 568). In experiment 2, 986 Angus crossbred multiparous suckled cows, at 7 locations in Virginia, were randomly assigned to one of two treatments: 1) Two doses of an injectable trace mineral (6 mL; Multimin® 90) at 118.3±17 days before calving and at 67.7±17.4 d of lactation (n = 494); or 2) negative control with no trace mineral injection (n = 492). All cows had ad libitum access to forage and water, and received additional mineral supplementation in form of mineral blocks. Calves were weaned at approximately 7 months of age, and 205-day AWW was calculated based on birth day, age of weaning and age of dam. No differences between treatments were detected for BW (33.7±1.01 kg; P = 0.50) and AWW (212.2±5.0 kg; P = 0.25) when only one dose of injectable trace mineral was administered to the dam at early lactation. Similarly, when two doses of injectable trace mineral were administrated BW (35.6±1.1 kg; P = 0.70) and AWW (259.4±6.1 kg; P = 0.83) did not differ between treatments. In conclusion, one or two doses of injectable trace mineral administrated at late gestation and/or during lactation had no effect on offspring BW and AWW.
PSV-3 Ovarian dynamics of brahman cows submitted to five-day or twelve-day progesterone-based estrus synchronization protocol
Authors: Filho Ramiro Oliveira , Paiva Rafael R , de Melo Gabriela Dalmaso , Cardoso Rodolfo C , Perry George A , Lamb G Cliff C , Pohler Ky G 
Published: October 2021

Abstract
The aim of this study was to investigate the ovarian response of Brahman cows submitted to two different estrus synchronization protocols and to determine the estrus response and ovulation time. A total of 153 Brahman cows were randomly assigned to receive one of the following estrus synchronization protocols: 1) CIDR insert and an injection of prostaglandin F2α (25 mg, PGF) on Day -5 and CIDR removal with PGF on Day 0 (CIDR5; n = 77); 2) CIDR insert on Day -12 and an injection of PGF on Day -12, Day -5 and Day 0 upon CIDR removal (CIDR12; n = 76). Estrotect breeding indicator patches were placed on Day 0 and cows were artificially inseminated (AI) 12h after estrus detection; cows not detected in estrus after 96h received TAI coupled with 100 µg of GnRH. Ovarian dynamics were observed during the protocol and follicular diameter were measured every 12h after AI until ovulation. Cows synchronized with CIDR12 had increased follicular diameter (CIDR5, 10.19 ± 0.51 vs. CIDR12, 13.12 ± 0.52 mm; P = 0.01) and decreased serum concentrations of progesterone (CIDR5, 1.68 ± 0.12 vs. CIDR12, 0.81 ± 0.12 ng/ml; P &lt; 0.01) at CIDR removal. The percentage of cows exhibiting estrus did not differ between treatments (CIDR5, 66.2 vs. CIDR12, 64.5%; P = 0.25). No difference was observed in ovulation rate (CIDR5, 94.1 vs. CIDR12, 94.1%; P = 0.6). Time of estrus expression and ovulation time after CIDR removal did not differ (CIDR5, 59.9 ± 2.3 vs. CIDR12, 61.5 ± 2.3h; P = 0.71 and CIDR5, 88.1 ± 2.6 vs. CIDR12, 90.9 ± 2.6h; P = 0.75; respectively). In conclusion, extended length of CIDR with additional PGF increased follicular diameter and decreased concentrations of progesterone but did not influence estrus response and ovulation time in Brahman cows.
PSII-17 The differential expression pattern of messenger RNA for key hepatic glycogen metabolizing proteins is consistent with hepatic glycogen content in suckling pigs
Authors: DeGiorgio Chloe , Elefson Sarah , Lindemann Merlin D , Matthews James C 
Published: October 2021

Abstract
The effect of developmental age (d) on expression of genes responsible for hepatic glycogen (GLY) synthesis and degradation, glucose flux, and GLY content, was determined in crossbred pigs euthanized (n = 6) at birth (d 0, pre-suckle), 1, 3, 7, 14, and 21 d. Liver GLY content and relative abundance of mRNA (RT-PCR) was determined. The relative content of liver mRNA was determined in 2 experiments, d 0, 1, 3, 7 (Experiment 1) and d 0, 1, 7, 14, 21 (Experiment 2). Within each experiment, data were analyzed using the GLM procedure of SAS. Fisher’s protected LSD procedure was used to separate treatment means. Day 0 (76.0) GLY content (mg/g) decreased (P &lt; 0.01) 82% from d 0 to d 1, increased (P &lt; 0.05) from d 1 (13.8) through d 14 (28.4), and did not differ (P = 0.07) between d 1 and 21. In Experiment 1, mRNA content of GLY synthesis proteins GYG1 and GYS1 was greatest (P &lt; 0.01) at d 3 and 7; and 1 and 3; respectively, whereas mRNA content of GLY degrading proteins PGM1, PGM2, and PGM5 was greatest (P ≤ 0.01) at d 1; d 0; and d 1 and 7; respectively. In Experiment 2, mRNA content of GLY synthesis proteins GBE1 and GYS1 was greatest (P &lt; 0.01) at d 0 and 21; and d 1 and 21; respectively, whereas mRNA content of GLY degrading proteins AGL, PGM2, PGM2L, and PGM5 was greatest (P &lt; 0.01) at d 21; d 0; d 7, 14, and 21; and d 14 and 21; respectively. Glucose transporter SGLT1 mRNA content was greatest (P &lt; 0.01) at d 14 and 21. These findings indicate that the pattern of mRNA content of key hepatic GLY degradation and synthesis proteins was consistent with GLY content of suckling pigs.
PSII-18 The effects of fish oil supplementation on markers of inflammation and skeletal muscle and adipose growth in pigs
Authors: Okamoto Lillian L , Reichhardt Caleb C , Lopez Sierra , Alberto Anthony F , Briggs Reganne K , Smith Laura A , Batistel Fernanda , Thornton Kara J 
Published: October 2021

Abstract
Omega-3 fatty acids have immunomodulatory and anti-inflammatory effects. The objective of this project was to determine the effects of fish oil, a source of omega-3 fatty acids, on genes involved in inflammation and growth of skeletal muscle tissue after an LPS challenge. Male Landrace-New Hampshire weaned piglets (BW 8.21±0.83 kg) were used in a randomized complete block design and assigned to two treatments: 1) basal diet (n=7) and 2) basal diet plus 3% fish oil added (n = 7). Treatments were fed for 35 d. On d 34, an LPS challenge was performed and 24 h later, piglets were euthanized and skeletal muscle samples were collected from the longissimus lumborum and biceps femoris. Total mRNA was isolated and markers of inflammation [cyclophilin (Cyclo), nuclear factor kappa beta subunit-1 (NF-kB), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6)], skeletal muscle growth [paired box transcription factor-7 (Pax7), myogenic factor-5 (Myf5), myoblast determination factor-1 (MyoD), myogenin (MyoG)] and adipose growth (peroxisome proliferator activated receptor (PPARy), leptin, and adiponectin) were analyzed. Cyclophilin abundance was increased (P = 0.03) in fish-oil piglets compared to control piglets. Other markers of inflammation (TNF-α, IL-6, NF-kB) were not affected (P &gt; 0.05) by fish-oil supplementation. Abundance of Myf5 was lower (P = 0.03) in fish oil piglets than control piglets. Other myogenic regulatory factors (Pax7, MyoD, MyoG) were not (P &gt; 0.05) altered by treatment. Abundance of PPARy, leptin or adiponectin was not affected (P &gt; 0.05) by fish-oil supplementation. Muscle location influenced (P &lt; 0.01) abundance of leptin and adiponectin, with abundance being higher in the biceps femoris than in the longissimus lumborum. No other genes analyzed were impacted by muscle location (P &gt; 0.05). Our findings suggest that supplementation of omega-3 fatty acids via fish-oil may affect the inflammatory response and skeletal muscle growth. Further research is needed to evaluate the impact of these results on animal production.
Arabidopsis fibrillin 1-2 subfamily members exert their functions via specific protein–protein interactions
Authors: Torres-Romero Diego , Gómez-Zambrano Ángeles , Serrato Antonio Jesús , Sahrawy Mariam , Mérida Ángel 
Published: October 2021

Abstract
Fibrillins (FBNs) are plastidial proteins found in photosynthetic organisms from cyanobacteria to higher plants. The function of most FBNs remains unknown. Here, we focused on members of the FBN subgroup comprising FBN1a, FBN1b, and FBN2. We show that these three polypeptides interact between each other, potentially forming a network around the plastoglobule surface. Both FBN2 and FBN1s interact with allene oxide synthase, and the elimination of any of these FBNs results in a delay in jasmonate-mediated anthocyanin accumulation in response to a combination of moderate high light and low temperature. Mutations in the genes encoding FBN1s or FBN2 also affect the protection of PSII under the combination of these stresses. Fully developed leaves of these mutants have lower maximum quantum efficiency of PSII (Fv/Fm) and higher oxidative stress than wild-type plants. These effects are additive, and the fbn1a-1b-2 triple mutant shows a stronger decrease in Fv/Fm and a greater increase in oxidative stress than fbn1a-1b or fbn2 mutants. Co-immunoprecipitation analysis indicated that FBN2 also interacts with other proteins involved in different metabolic processes. We propose that these fibrillins facilitate accurate positioning of different proteins involved in distinct metabolic processes, and that their elimination leads to dysfunction of those proteins.
Progenitor and close-in circumstellar medium of type II supernova 2020fqv from high-cadence photometry and ultra-rapid UV spectroscopy
Authors: Tinyanont Samaporn , Ridden-Harper R , Foley R J , Morozova V , Kilpatrick C D , Dimitriadis G , DeMarchi L , Gagliano A , Jacobson-Galán W V , Messick A , Pierel J D R , Piro A L , Ramirez-Ruiz E , Siebert M R , Chambers K C , Clever K E , Coulter D A , De K , Hankins M , Hung T , Jha S W , Jimenez Angel C E , Jones D O , Kasliwal M M , Lin C-C , Marques-Chaves R , Margutti R , Moore A , Pérez-Fournon I , Poidevin F , Rest A , Shirley R , Smith C S , Strasburger E , Swift J J , Wainscoat R J , Wang Q , Zenati Y 
Published: October 2021

ABSTRACT
We present observations of SN 2020fqv, a Virgo-cluster type II core-collapse supernova (CCSN) with a high temporal resolution light curve from the Transiting Exoplanet Survey Satellite (TESS) covering the time of explosion; ultraviolet (UV) spectroscopy from the Hubble Space Telescope (HST) starting 3.3 d post-explosion; ground-based spectroscopic observations starting 1.1 d post-explosion; along with extensive photometric observations. Massive stars have complicated mass-loss histories leading up to their death as CCSNe, creating circumstellar medium (CSM) with which the SNe interact. Observations during the first few days post-explosion can provide important information about the mass-loss rate during the late stages of stellar evolution. Model fits to the quasi-bolometric light curve of SN 2020fqv reveal 0.23 M⊙ of CSM confined within 1450 R⊙ (1014 cm) from its progenitor star. Early spectra (&lt;4 d post-explosion), both from HST and ground-based observatories, show emission features from high-ionization metal species from the outer, optically thin part of this CSM. We find that the CSM is consistent with an eruption caused by the injection of ∼5 × 1046 erg into the stellar envelope ∼300 d pre-explosion, potentially from a nuclear burning instability at the onset of oxygen burning. Light-curve fitting, nebular spectroscopy, and pre-explosion HST imaging consistently point to a red supergiant (RSG) progenitor with $M_{\rm ZAMS}\approx 13.5\!-\!15 \, \mathrm{M}_{\odot }$, typical for SN II progenitor stars. This finding demonstrates that a typical RSG, like the progenitor of SN 2020fqv, has a complicated mass-loss history immediately before core collapse.
Two c’s in a pod: cosmology-independent measurement of the Type Ia supernova colour–luminosity relation with a sibling pair
Authors: Biswas Rahul , Goobar Ariel , Dhawan Suhail , Schulze Steve , Johansson Joel , Bellm Eric C , Dekany Richard , Drake Andrew J , Duev Dmitry A , Fremling Christoffer , Graham Matthew , Kim Young-Lo , Kool Erik C , Kulkarni Shrinivas R , Mahabal Ashish A , Perley Daniel , Rigault Mickael , Rusholme Ben , Sollerman Jesper , Shupe David L , Smith Matthew , Walters Richard S 
Published: October 2021

ABSTRACT
Using Zwicky Transient Facility (ZTF) observations, we identify a pair of ‘sibling’ Type Ia supernovae (SNe Ia), i.e. hosted by the same galaxy at z = 0.0541. They exploded within 200 d from each other at a separation of $0.6\,\mathrm{ arcsec}$ corresponding to a projected distance of only 0.6 kpc. Performing salt2 light-curve fits to the gri ZTF photometry, we show that for these equally distant ‘standardizable candles’, there is a difference of 2 mag in their rest-frame B-band peaks, and the fainter supernova (SN) has a significantly red salt2 colour c = 0.57 ± 0.04, while the stretch values x1 of the two SNe are similar, suggesting that the fainter SN is attenuated by dust in the interstellar medium of the host galaxy. We use these measurements to infer the salt2 colour standardization parameter, β = 3.5 ± 0.3, independent of the underlying cosmology and Malmquist bias. Assuming the colour excess is entirely due to dust, the result differs by 2σ from the average Milky Way total-to-selective extinction ratio, but is in good agreement with the colour–brightness corrections empirically derived from the most recent SN Ia Hubble–Lemaitre diagram fits. Thus we suggest that SN ‘siblings’, which will increasingly be discovered in the coming years, can be used to probe the validity of the colour and light-curve shape corrections using in SN Ia cosmology while avoiding important systematic effects in their inference from global multiparameter fits to inhomogeneous data sets, and also help constrain the role of interstellar dust in SN Ia cosmology.
Super stellar abundances of alkali metals suggest significant migration for hot Jupiters
Authors: Hands Tom O , Helled R 
Published: October 2021

ABSTRACT
We investigate the origin of the measured overabundance of alkali metals in the atmospheres of hot gas giants, relative to both their host stars and their atmospheric water abundances. We show that formation exterior to the water snow line followed by inward disc-driven migration results in excess accretion of oxygen-poor, refractory-rich material from within the snow-line. This naturally leads to enrichment of alkali metals in the planetary atmosphere relative to the bulk composition of its host star but relative abundances of water that are similar to the stellar host. These relative abundances cannot be explained by in situ formation which places the refractory elements in the planetary deep interior rather than the atmosphere. We therefore suggest that the measured compositions of the atmospheres of hot Jupiters are consistent with significant migration for at least a subset of hot gas giants. Our model makes robust predictions about atmospheric composition that can be confirmed with future data from JWST and Ariel.
New constraints on the minimum mass for thermonuclear lithium burning in brown dwarfs
Authors: Martín E L , Lodieu N , del Burgo C 
Published: October 2021

ABSTRACT
The theory of substellar evolution predicts that there is a sharp mass boundary between lithium and non-lithium brown dwarfs, not far below the substellar-mass limit. The imprint of thermonuclear burning is carved on the surface lithium abundance of substellar-mass objects during the first few hundred million years of their evolution, leading to a sharp boundary between lithium and non-lithium brown dwarfs, so-called, the lithium test. The theoretical predictions can be tested by comparing with observations of lithium in the individual components of binaries with dynamical masses measured from orbital motions. New optical spectroscopic observations of the binaries DENIS J063001.4−184014AB and DENIS J225210.7−173013AB obtained using the 10.4-m Gran Telescopio de Canarias are reported here. They allow us to re-determine their combined optical spectral types (M9.5 and L6.5, respectively) and to search for the presence of the Li i resonance doublet. The non-detection of the Li i feature in the combined spectrum of DENIS J063001.4−184014AB is converted into estimates for the depletion of lithium in the individual components of this binary system. In DENIS J225210.7−173013AB, we report the detection of a weak Li i feature which we tentatively ascribe as arising from the contribution of the T3.5-type secondary. Combining our results with data for seven other brown dwarf binaries in the literature treated in a self-consistent way, we confirm that there is indeed a sharp transition in mass for lithium depletion in brown dwarfs, as expected from theoretical calculations. We estimate such mass boundary is observationally located at 51.48$^{+0.22}_{-4.00}\, M_\mathrm{Jup}$, which is lower than the theoretical determinations.
ALMA observations of the Extended Green Object G19.01−0.03 – I. A Keplerian disc in a massive protostellar system
Authors: Williams G M , Cyganowski C J , Brogan C L , Hunter T R , Ilee J D , Nazari P , Kruijssen J M D , Smith R J , Bonnell I A 
Published: October 2021

ABSTRACT
Using the Atacama Large Millimetre/submillimeter Array (ALMA) and the Karl G. Jansky Very Large Array (VLA), we observed the Extended Green Object (EGO) G19.01−0.03 with sub-arcsec resolution from 1.05 mm to 5.01 cm wavelengths. Our ∼0.4 arcsec ∼ 1600 au angular resolution ALMA observations reveal a velocity gradient across the millimetre core MM1, oriented perpendicular to the previously known bipolar molecular outflow, which is consistently traced by 20 lines of 8 molecular species with a range of excitation temperatures, including complex organic molecules (COMs). Kinematic modelling shows the data are well described by models that include a disc in Keplerian rotation and infall, with an enclosed mass of 40–70 M⊙ (within a 2000 au outer radius) for a disc inclination angle of i = 40○, of which 5.4–7.2 M⊙ is attributed to the disc. Our new VLA observations show that the 6.7 GHz Class II methanol masers associated with MM1 form a partial ellipse, consistent with an inclined ring, with a velocity gradient consistent with that of the thermal gas. The disc-to-star mass ratio suggests the disc is likely to be unstable and may be fragmenting into as-yet-undetected low-mass stellar companions. Modelling the centimetre–millimetre spectral energy distribution of MM1 shows the ALMA 1.05 mm continuum emission is dominated by dust, whilst a free–free component, interpreted as a hypercompact H ii region, is required to explain the VLA ∼5 cm emission. The high enclosed mass derived for a source with a moderate bolometric luminosity (∼104 L⊙) suggests that the MM1 disc may feed an unresolved high-mass binary system.
A detailed study of the bridge of excess X-ray emission between the galaxy clusters Abell 2029 and Abell 2033
Authors: Mirakhor M S , Walker S A , Runge J 
Published: October 2021

ABSTRACT
We examine Suzaku, XMM–Newton, and Chandra observations of the Abell 2029/2033 system to investigate the nature of a bridge of X-ray emission joining the two galaxy clusters. By modelling the contributions from the outskirts of the two clusters, and excluding the emission from the southern infalling group and the background group LOS9, we find a significant excess of X-ray emission between the two clusters at the level of 6.5–7.0σ, depending on the choice of model, that cannot be explained by the overlap of the clusters. This excess component to the surface brightness is consistent with being emission from a filament with roughly 1.0 Mpc wide. The derived emission measure for the gas associated with the filament yields an average gas density of $3.7^{+1.0}_{-0.7} \times 10^{-5}$ cm−3, corresponding roughly to 160 times the mean baryon density of the Universe. The Suzaku X-ray spectrum of the excess emission indicates that it is significantly colder ($1.4_{-0.5}^{+0.7}$ keV) than the cluster outskirts emission from the two clusters (∼5 keV), statistically consistent with the temperature expected from the hottest and densest parts of the warm–hot intergalactic medium. The geometry, density, and temperature are similar to those found from X-ray studies of the Abell 222/223 filament.