bluuebunny/crossref_metadata_2025_split huggingface dataset:
Toward a “human being to commodity model” as an explanation for men's violent, sexual consumption of women
Authors: Yeh Marie A. , Eilert Meike , Vlahos Aphrodite , Baker Stacey Menzel , Stovall Tony 
Published: May 2021

AbstractThis research proposes a consumer behavior model that highlights how women may be valuated across a continuum of living human being to commodity. We use the social epidemic of men's sexual violence against women to build a model that reframes sexual violence as men's violent consumption of women. Our model describes the process through which men can think about women as a commodity. We propose different paths through which commoditization occurs—men perceiving women as instrumental, interchangeable, and violable, as well as denying their subjectivity and autonomy—which can lead to violent consumption (the commitment of sexual violence). While sexual violence is a complex problem that defies easy solutions, we believe our nuanced and concrete model is more informative to actions to stop sexual violence than existing theories. We also discuss the role of other factors, including the marketplace, in enabling, attenuating, and reversing this process.
The influence of time, resource, and gender ideology on the division of domestic work in Korea
Authors: Ryu Soomin , Kim Jinhee 
Published: May 2021

AbstractThe paper examines how time availability, relative monetary contribution, and gender ideology are related to a couple's contribution to domestic work in South Korea, using data from the Korean Longitudinal Survey of Women and Families. OLS regressions with fixed effects indicate that couples' hours worked were significantly associated with their own and their spouse's time spent on domestic work. The wife's relative wage was another essential determinant in the division of domestic work between wife and husband. Although the wife's gender ideology was not a significant factor for her domestic work time, a husband whose wife had more gender‐equitable attitudes was more likely to devote time to domestic work. Going beyond earlier studies, we also present new evidence for gender display: the wife's relative wage had a curvilinear relationship with the couple's time spent on domestic work. The broader implications of the main findings are also discussed.
Understanding digital consumers' well‐being in Asia: The moderating roles of digital natives and privacy concerns
Authors: Kwak Youshin , Kim Jeeyeon , Kim Yeolib , Choi Jeonghye 
Published: May 2021

AbstractAs digital technologies permeate our lives, the effect of digital device use on well‐being has become a hot‐button issue. In this research, we focus on digital usage and digital shopping via online and mobile devices and investigate their relationships with well‐being using a public data from South Korea. Overall, online usage and online shopping increase well‐being, whereas mobile usage and mobile shopping decrease it. Interestingly, these relationships are complex and idiosyncratic as including digital natives and privacy concerns as moderators provides varied results. Among digital natives, the positive effect of online usage on well‐being decreases whereas the negative effects of mobile usage and mobile shopping on well‐being increase. Furthermore, privacy concerns weaken the effects of mobile usage and online shopping on well‐being.
Association between resistin gene (−420 C > G) polymorphism and acne vulgaris
Authors: Akcılar Raziye , Dizen Namdar Nazlı , Arslan Utku Selve 
Published: May 2021

AbstractBackgroundAcne vulgaris (AV) is the most prevalent inflammatory skin disease and develops on the face and upper trunk. Resistin, a member of the cysteine‐rich secretory proteins family, is an adipokine expressed primarily in macrophages and monocytes; it has a role to play in the inflammatory period.AimsThis study's purpose was to detect whether known resistin gene (−420 C > G) polymorphism plays a role in the pathogenesis of AV.MethodsPatients with AV (n = 94) and healthy controls (n = 94) were enrolled in this investigation. Resistin gene (−420 C > G) polymorphism was decided by PCR‐RFLP procedure.ResultsThe distribution of genotype frequencies of resistin gene (−420 C > G) polymorphism was significantly different between the AV and healthy controls (p = 0.002). We found that the resistin gene (−420 C > G) CG genotype exhibited a significant association with decreased acne vulgaris risk.ConclusionsOur study is the first report investigating the relationship between the risk of AV and resistin gene (−420 C > G) polymorphism in the Turkish population. Resistin gene (−420 C > G) polymorphism is related to AV pathogenesis. CG genotype has a protective role and may be linked to a reduced risk of AV development. Furthermore, studies are needed to verify these findings in other populations.
Estimation of energy expenditure using the oral 13C‐bicarbonate technique in privately owned adult and senior dogs of three different body sizes
Authors: Marcussen Caroline , Jørgensen Ea Meng , Lemire‐Dilling Nickie , Tauson Anne‐Helene 
Published: May 2021

AbstractKnowledge about energy requirements (ER) of dogs is important in order to provide dogs with an appropriate energy supply. In this study, the oral 13C‐bicarbonate technique (o13CBT) was used to estimate energy expenditure (EE) in 50 privately owned dogs of different body sizes (small: Danish–Swedish Farmdog (DSF, n = 16), medium: Beagle (n = 15), large: Labrador Retriever (n = 19)), of different ages (adult: 2–7 years (n = 33), senior: ≥8 years (n = 17)). The aim was to evaluate the feasibility of the method in the field and to get more information about ER of dogs. All dogs were measured twice, on two separate days under standardized, resting conditions. The dogs were fasted overnight prior to measurements, which were carried out in home environment. Only measurements of dogs resting calmly were included in the statistical analyses. No significant difference (p > 0.05) in EE was found between days of measurements. The EE measured in Labrador Retrievers (405 kJ (97 kcal)/kg BW0.75/day) was significantly lower (p < 0.001) than of Beagles (530 kJ (127 kcal)/kg BW0.75/day) and DSF (497 kJ (119 kcal)/kg BW0.75/day), the difference between Beagles and DSF being non‐significant. Senior dogs had significantly lower (p < 0.001) EE values than adult dogs with least square means (LSM) of 441 kJ (105 kcal)/kg BW0.75/day and 513 kJ (123 kcal)/kg BW0.75/day respectively. Analysed within breeds, EE of senior Labrador Retrievers (370 kJ (88 kcal)/kg BW0.75/day)) was significantly lower (p < 0.01) than adults (439 kJ (105 kcal)/kg BW0.75/day), as well as in DSF (453 kJ (108 kcal)/kg BW0.75/day and 541 kJ (129 kcal)/kg BW0.75/day for senior and adult dogs respectively). However, the EE was not significantly different (p > 0.05) between adult (548 kJ (131 kcal)/kg BW0.75/day) and senior (499 kJ (119 kcal)/kg BW0.75/day) Beagles. This study suggests that when measured under standardized resting conditions, the o13CBT can provide reliable results of EE and be a helpful tool to get more knowledge about ER of dogs of different sizes, breeds and ages.
Grapiprant: A snapshot of the current knowledge
Authors: Sartini Irene , Giorgi Mario 
Published: May 2021

AbstractGrapiprant is the pioneer member of the novel piprant class, a potent and specific antagonist of the prostaglandin E2 receptor 4. It has been approved in veterinary medicine for the control of pain and inflammation associated with osteoarthritis in dogs at the dose regimen of 2 mg/kg once a day by the FDA and EMA (for pain only) in 2016 and 2018, respectively. The aim of this narrative review was to report the analytical methods, pharmacokinetics, pharmacodynamics and safety of grapiprant in several animal species using the best available published scientific evidence. In conclusion, most of the analytical methods proposed for grapiprant detection are simple, reliable, sensitive and validated. The pharmacokinetics show discrepancies between animal species. The therapeutic efficacy seems more suited to chronic rather than acute pain.
A genetic variant in toll‐like receptor 5 is linked to chemokine levels and hepatocellular carcinoma in steatohepatitis
Authors: Nischalke Hans Dieter , Fischer Janett , Klüners Alexandra , Matz‐Soja Madlen , Krämer Benjamin , Langhans Bettina , Goeser Felix , Soyka Michael , Stickel Felix , Spengler Ulrich , Nattermann Jacob , Strassburg Christian P. , Berg Thomas , Lutz Philipp 
Published: May 2021

AbstractBackground & AimsBacterial translocation drives liver disease progression. We investigated whether functional genetic variants in toll‐like receptor 5 (TLR5), the receptor for bacterial flagellin, affect the risk for hepatocellular carcinoma (HCC).MethodsHealthy controls (n = 212), patients with alcohol abuse without liver disease (n = 382), and patients from a discovery cohort of alcohol‐associated cirrhosis (n = 372 including 79 HCC cases), a validation cohort of alcohol‐associated cirrhosis (n = 355 including 132 HCC cases), and a cohort of cirrhosis due to nonalcoholic steatohepatitis (NASH) (n = 145 including 62 HCC cases) were genotyped for the TLR5 rs5744174 and rs5744168 polymorphisms. Chemokine levels were measured by ELISA in patients' sera and supernatants of flagellin‐stimulated healthy monocytes.ResultsFrequency of the TLR5 rs5744174 TT genotype was similar in healthy controls (33%), controls with alcohol abuse (34%), and patients with alcohol‐associated cirrhosis in the discovery (28%), validation (33%), and NASH cohort (31%). The TT genotype was enriched in patients with versus without HCC in the discovery, validation, and NASH cohort (41% vs 25%; 39% vs 29%; 40% vs 24%; p < .05 each). This genotype remained a risk factor for HCC (OR = 1.9; p = .01) after multivariate correction for age, gender, diabetes, and carriage of the PNPLA3 148M variant. Interleukin‐8 induction in monocytes from healthy controls and serum levels of interleukin‐8 and CXCL1 from cirrhotic patients with the TT genotype were significantly increased versus C allele carriers.ConclusionThe TLR5 rs5744174 polymorphism, affecting immune response to flagellin, is linked to occurrence of HCC in cirrhosis caused by steatohepatitis.
An open‐label non‐inferiority randomised control trial comparing nebulised amphotericin B with oral itraconazole in patients with pulmonary aspergilloma
Authors: Ray Animesh , Manikanta Jagdeesh , Singh Komal , Gabra Pavan , Vyas Surabhi , Singh Gagandeep , Xess Immaculata , Sethi Prayas , Meena Ved Prakash , Soneja Manish , Sinha Sanjeev , Wig Naveet , Kabra SK 
Published: May 2021

AbstractBackgroundPulmonary aspergilloma (PA) is a common complication seen in patients with pulmonary tuberculosis sequelae. Antifungal therapy, including oral azoles, is commonly used though only surgical resection offers curative benefit. Local administration of amphotericin B, like intracavitary instillation, has been effective in aspergilloma patients though nebulised amphotericin B (nAB) has never been formally assessed.ObjectiveThe aim of this prospective, non‐inferior, open‐label, randomised control trial is to evaluate the efficacy and safety of nebulised amphotericin B compared to oral itraconazole therapy in the treatment of PA.Patients/MethodsDiagnosed cases of PA (n=33) were randomised into the control group receiving oral itraconazole (n=18) and intervention group receiving nebulised amphotericin B (n = 15). Response to treatment was assessed both clinically and radiologically at the end 6 months.Results and ConclusionThe number of patients showing overall improvement at the end of 6 months in the control arm(oral itraconazole) vs intervention arm(nebulised amphotericin B) was 65% (95% CI 38.3–85.8) and 67%(95% CI 38.4%–88.2%), respectively, in the intention‐to‐treat and 79% (95% CI 49.2%–95.3%), and 65% (95% CI 38.4%–88.2%), respectively, in the per‐protocol analysis. While there was no statistically significant difference between the intervention and control arm in both the analyses, non‐inferiority was shown in the per‐protocol but not in the intention‐to‐treat analysis. No major adverse events were noted in either group; however, a significant proportion of patients receiving nAB reported minor cough (40%), which, however, did not lead to discontinuation of therapy in any patients. Nebulised amphotericin B can be an effective therapeutic option for pulmonary aspergilloma patients.
Identifying associations between dental arch relationship scores, relative deprivation and other cleft audit outcomes. Part 2
Authors: Sullivan Zak Christopher , Van Eeden Simon , May Joanna , Flannigan Norah , Seshu Madhavi , Dominguez‐Gonzalez Susana 
Published: May 2021

AbstractIdentify associations between dental arch relationship scores, oral health status and deprivation index in patients with complete unilateral cleft lip and palate (UCLP) and bilateral cleft lip and palate (BCLP). Ninety‐two 5‐year‐old children with non‐syndromic complete UCLP and thirty‐nine 5‐year‐old children with non‐syndromic complete BCLP from the United Kingdom. Data were collected from the 5‐year audit outcomes submitted to the Cleft Registry and Audit Network (CRANE). The index of multiple deprivation (IMD) and Welsh index of deprivation were used to assess a relative measure of deprivation. Comparisons of 5‐year‐old index/BCLP Deciduous Dentition Yardstick outcome against IMD and dmft are performed using multivariable linear regression models. Both UCLP and BCLP had a high percentage of children with dmft >0 (47% and 49%, respectively). The mean dmft for the UCLP cohort was 2.8 and 2.6 for the BCLP cohort. In the UCLP group, a poorer 5‐year‐old index was associated with an increased dmft score (P = .023) and higher level of deprivation (P = .010). In the BCLP group, there was no significant associations between BCLP Deciduous Dentition Yardstick, dmft and IMD. A poorer dental arch relationship outcome may be associated with higher level of area deprivation and oral health status, in children with UCLP. Those with a poor outcome for the 5‐year‐old Index are more likely to have increased caries experience.
Situation analyses of caregivers’ knowledge on infant liquid formula in Japan: a cross‐sectional questionnaire‐based study
Authors: Mizutani Shinichiro , Takahashi Kenzo , Matsuura Masaaki 
Published: May 2021

AbstractBackgroundSales of the first domestic liquid infant milk formula in Japan started in March 2019, and some local governments have started to stockpile the formula in case of disasters. This study aimed to assess caregivers’ knowledge of liquid formula to promote better utilization during disaster situations.MethodsA cross‐sectional, questionnaire‐based study was conducted between August 26 and October 4, 2019, in Aiiku Hospital and Aiiku Clinic (Minato Ward, Tokyo, Japan). Caregivers of infants at their 1‐, 3–4‐, and 6–7‐month medical check‐ups participated. Caregivers’ knowledge about the cup feeding method and handling of residual (left over) formula was evaluated. Caregivers were divided into high or low knowledge groups. Logistic regression analysis was performed to analyze the relation between caregivers’ information sources on liquid formula and each caregiver’s level of knowledge (high or low).ResultsOnly 10.5% of caregivers were included in the high knowledge group regarding the cup feeding method, whereas 83.1% of caregivers were included in the high knowledge group regarding handling of residual liquid formula. Only 8.1% of caregivers were included in the high knowledge group regarding both cup feeding and handling of residual liquid formula. Logistic regression analysis showed that none of the information sources (hospital/clinic, TV/newspaper/magazine/website, milk company’s website/advertisements, retail store, study meeting/event/social networking service, friend/infant’s grandmother, workplace) affected the caregivers’ knowledge.ConclusionsCaregivers’ knowledge on the cup feeding method and handling of left over liquid formula was insufficient. Proactive and correct provision of information is required to improve caregivers’ knowledge as this is an urgent infant safety issue in disaster situations.
Effect of different parietal hypoperfusion on neuropsychological characteristics in mild cognitive impairment
Authors: Yamaguchi Tatsuya , Tabuchi Hajime , Ito Daisuke , Saito Naho , Yamagata Bun , Konishi Mika , Takebayashi Minoru , Ikeda Manabu , Mimura Masaru 
Published: May 2021

AbstractBackgroundIn early‐stage amnestic mild cognitive impairment (aMCI), differences in the neuropsychological characteristics of each individual are subtle. We investigated differences in neuropsychological performance between aMCI patients with and without hypoperfusion in the medial parietal regions (MP). We further compared patients with hypoperfusion in the left and right lateral parietal regions.MethodsWe examined 165 aMCI patients (mean age: 76.8 ± 5.5 years; 87 women) who had undergone neuropsychological measurement and single‐photon emission computed tomography. We classified participants into two subgroups with and without hypoperfusion: MP hypoperfusion (+) and MP hypoperfusion (−); classification was based on Z‐scores (calculated by three‐dimensional stereotactic surface projection technique) of three regions of interest in the parietal lobes (i.e. MP regions including posterior cingulate cortex and precuneus and left and right inferior parietal lobules (lateral parietal regions)). The MP hypoperfusion (−) group was classified into left lateral parietal hypoperfusion (+) and right lateral parietal hypoperfusion (+) subgroups. We performed either univariate or multivariate ancova to compare neuropsychological scores for continuous variables between groups and examined dichotomous variables using χ2 tests.ResultsIn the overall aMCI sample, scores on logical memory delayed recall in the MP hypoperfusion (+) group were significantly lower than those in the MP hypoperfusion (−) group. Total scores on Rey‐Osterrieth Complex Figure Test delayed recall were also marginally lower in the MP hypoperfusion (+) group than in the MP hypoperfusion (−) group. Comparisons of neuropsychological test scores between the left and right lateral parietal hypoperfusion (+) groups revealed no significant differences.ConclusionsThe present findings suggest that MP hypoperfusion (+) is associated with more robust memory deficits than MP hypoperfusion (−). Combining neuropsychological tests and single‐photon emission computed tomography findings may be useful for early detection of cognitive decline in aMCI.
New revival phenomena for linear integro–differential equations
Authors: Boulton Lyonell , Olver Peter J. , Pelloni Beatrice , Smith David A. 
Published: May 2021

AbstractWe present and analyze a novel manifestation of the revival phenomenon for linear spatially periodic evolution equations , in the concrete case of three nonlocal equations that arise in water wave theory and are defined by convolution kernels. Revival in these cases is manifested in the form of dispersively quantized cusped solutions at rational times. We give an analytic description of this phenomenon, and present illustrative numerical simulations.
The Janus‐faced effects of COVID‐19 perceptions on family healthy eating behavior: Parent’s negative experience as a mediator and gender as a moderator
Authors: Mahmoud Ali B. , Hack‐Polay Dieu , Fuxman Leonora , Nicoletti Maria 
Published: May 2021

This research examines the effects of COVID‐19 perceptions and negative experiences during the pandemic time on parental healthy eating behavior and whether these relationships interact with a parent’s gender. We ran a survey of parents who had at least one child aged 3 to 17 years old living in the United Kingdom. We received 384 valid responses, which were analysed via a variance‐based structural equation modeling approach to test our hypotheses. The results revealed that COVID‐19 perceptions effects were Janus‐faced. While they indirectly and negatively impact healthy eating behavior mediated by triggering negative experiences during the pandemic, COVID‐19 perceptions, however, directly get parents, especially fathers, more engaged into healthy eating behavior – making COVID‐19 perceptions total effects positive on healthy eating behavior. This explorative model is novel in the sense that it is the first of its kind to cast light on how parental healthy eating behavior can be shaped in pandemic time. The research is particularly timely due to the uncertain times in which the research is situated, that is, the worldwide pandemic (also termed COVID‐19); the paper highlights how family eating practices can undergo dramatic shifts during acute crises.
The elusive link between eye‐movement patterns and facial expression recognition
Authors: Yitzhak Neta , Pertzov Yoni , Aviezer Hillel 
Published: May 2021

AbstractDifferent stereotypical facial expressions convey unique signals of muscular activity in distinct face regions. For example, the recognition of anger relies on decoding the downward drawing of the brows, while disgust recognition relies on decoding nose wrinkling and upper lip raising. Therefore, it is reasonable to assume that one’s ability to identify a facial expression is strongly influenced by the facial features that gaze was fixated upon. Indeed, a large body of research supports the claim that facial fixation distributions and emotion recognition are strongly associated: fixating information‐rich regions enhances emotion recognition, while suboptimal face‐scanning impedes it. Here, we offer a critical assessment of whether the data support this link. We critically review several bodies of research, examining the relationship between gaze exploration of facial expressions and emotion recognition, across different cultures, neuropsychological conditions, age, gender, as well as personal tendencies of facial visual exploration and different experimental conditions. Integrating results from these diverse fields suggests that compelling evidence regarding the manner that emotion recognition relies on visual scanning patterns has yet to emerge. While it is clear that certain facial features are differentially diagnostic for stereotypical emotion recognition, how that information is sampled and extracted remains elusive. We suggest that the dominant approach of examining the distribution of fixation locations may not be sufficient for solving this puzzle. Rather, using more complex eye‐tracking analyses and taking into account the extrafoveal processing are crucial for revealing the contribution of visual scanning to emotion recognition.
Formation of the Yangtze Three Gorges: Insights from detrital apatite fission‐track dating of sediments from the Jianghan Basin
Authors: Yang Chaoqun , Shen Chuanbo , Zattin Massimiliano , Yu Wu 
Published: May 2021

AbstractThe establishment of the course of the modern Yangtze River is a topic of ongoing debate, with the formation of the Three Gorges, incised in the Huangling Massif, representing the key event under discussion. Downstream of the Three Gorges, the Cenozoic succession of the Jianghan Basin has been investigated to detect the moment of incision into the Three Gorges. Detrital apatite fission‐track data from Eocene to Miocene sediments drilled in the Jianghan Basin suggest that material was supplied by the Dabie, Qinling and Jiangnan Orogens during Eocene to early Oligocene times. At late Oligocene, the source of sediments switched to the Huangling Massif, implying incision of the Three Gorges. We therefore propose that the modern Yangtze River system formed at the late Oligocene.