bluuebunny/crossref_metadata_2025_split huggingface dataset:
Obstetrics student satisfaction with the use of video channels as a support method in the learning process
Authors: Vasco-Morales Santiago , Toapanta-Pinta Paola 
Published: April 2021

El internet con sus herramientas como las redes sociales y canales de video se ha convertido en un importante apoyo en la educación superior y también en las ciencias médicas. Dentro de este contexto es importante conocer el nivel de satisfacción del estudiante con las propuestas y métodos pedagógicos implementados por los docentes.
Objetivo: Establecer el nivel de satisfacción de los estudiantes de la carrera de Obstetricia, con el uso del canal de videos YouTube, en el aprendizaje de asignaturas básicas y clínicas.
Sujetos y método: Estudiantes matriculados que asisten regularmente a clases de primero y cuarto semestre de la carrera de Obstetricia – Universidad Central del Ecuador. Se evaluó las respuestas estandarizadas de una encuesta de satisfacción usando el programa estadístico SPSS
Resultado y conclusiones: Se encontró un grado de satisfacción positivo y conveniente acerca de la utilización de videos a través del canal YouTube, como instrumento de apoyo en el aprendizaje, por lo que se debe aprovechar estas plataformas para la difusión de videos didácticos e incentivar su uso.
Recomendamos hacer estudios prospectivos de cohortes para evaluar el impacto de los videos educativos en el proceso de aprendizaje.
SPERMIDINE MAINTAINS TELOMERE LENGTH AND DELAYS AGING
Authors: Sharma Priyanka , Jaiswal Rishi Kumar 
Published: April 2021

Spermidine, a natural polyamine, has been noticed for its anti-aging properties. Supplementation of this drug prolongs lifespan and diminishes the incidence of age-related pathology. In the human population, spermidine levels decrease as aging progresses, and a potential link between diminished endogenous spermidine levels and age-related declination has been studied. At the cellular level, autophagy is the prime mode of action of spermidine known to decline with the progress of aging, similarly contributing to the accretion of impaired macromolecules and organelles through aging. Epidemiological statistics support the concept, suggesting that elevated uptake of polyamine delays aging. Here, we overview the effect of autophagy on cellular processes and age-associated diseases, emphasizing the importance of these events to the hallmarks of aging.
There are numerous factors like shortening telomere, oxidative stress, mitochondrial damage, and impaired intracellular calcium signaling, which are influenced by the aging process. We hypothesize that spermidine supplements in the diet increase the telomere length. The proposed hypothesis also brings to light the differentially regulated genes involved in telomere maintenance and aging after spermidine treatment. Knowing the role of spermidine in telomere maintenance would help us understand the molecular mechanism of spermidine's effect on aging.
The frequency of non-alcoholic fatty liver disease in non-obese young medical professionals
Authors: Bilal Aziz  , Tazeen Nazar  , Muhammad Irfan  
Published: April 2021

Abstract
This cross-sectional study was conducted in Mayo Hospital, Lahore, from July 16, 2018 to January 15, 2019 to observe the frequency of occurrence of non-alcoholic fatty liver disease in non-obese young medical professionals. One hundred and fifty-three subjects were selected using Simple Random Sampling Technique. SPSS version 25.0 was used to analyse the data. Out of a total of 153 medical professionals, 67 (43.8%) were males and 86 (56.2%) were females, median age was 23 years (inter-quartile range of 5 years), mean BMI was 22.79 + 1.57 kg/m2, 122 (79.7%) subjects had normal texture of liver on ultrasonography and normal ALT levels, 21 (13.7%) had fatty liver with normal ALT levels, and 10 (6.5%) had fatty liver and elevated ALT levels (NASH). NAFLD and NASH are common ultrasonographic findings in seemingly healthy young adults with normal BMI. Awareness programmes should be carried out at the national level to educate the general public about the prevention and treatment of this disease through lifestyle and dietary modifications.
Continuous...
Salicin a promising ER, PR and HER2 binding molecule proving lethal against Hormone + and triple negative breast cancer cells
Authors: Vekaria Mrudul Pravinbhai , Tirgar Pravin 
Published: April 2021

Therapeutics against breast cancer is a major research field, due to inefficiency or partial efficiency of existing therapeutics. An urge to discover better therapeutics always persists. Our objective is to study salicin against breast cancer cells, in order to find its therapeutic properties. To study the effect of salicin on breast cancer cells, we performed MTT assay on MCF-7 (hormone positive) and MDA-MB-231 (triple negative) breast cancer cell lines, we did brine shrimp lethality test (BSLT) assay to see the lethal effects of salicin. By the help of bioinformatics we tried to locate the targets that delineate salicin activity. Salicin was docked with estrogen receptor (ER), progesterone receptor (PR) and Human epidermal growth factor receptor 2 (HER2) to study its binding efficiency and possible targets of salicin. Salicin remarkably reduces cell viability both in MCF-7 and MDA-MB-231, along with being lethal to brine shrimps. These results together opine that salicin can be an effective therapeutics against breast cancer cells. The mechanism of action of salicin is probably through ER, PR and HER2 receptors because it can efficiently bind these receptors with minimum energy required for binding. This explains that salicin can easily bind to these receptors. These results together opine that salicin can be an effective therapeutics against breast cancer cells. The mechanism of action of salicin is probably through ER, PR and HER2 receptors because it can efficiently bind these receptors with minimum binding energy. ER, PR and HER2 are major reasons behind the disease pathogenicity depending on the type of breast cancer. According to our results salicin may either induce apoptosis or reduce cellular mitosis both via P53 dependent and independent pathway, which makes salicin a good choice of both hormone positive and negative breast cancer cells.
Ứng dựng nghiên cứu địa hóa trầm tích nông trong tìm kiếm thăm dò dầu khí trên biển và thềm lục địa Việt Nam
Authors: Le Hoai Nga  , Phi Ngoc Dong  , Do Manh Toan  , Nguyen Thi Thanh  , Nguyen Thi Tuyet Lan  , Nguyen Hoang Son  , Ho Thi Thanh  , Dao Ngoc Huong  , Bui Quang Huy  , Nguyen Thi Thanh Thuy  , Nguyen Thi Tham  , Nguyen Thi Thanh Nga  
Published: April 2021

Nghiên cứu địa hóa bề mặt đã được ứng dụng trong tìm kiếm thăm dò dầu khí hơn 100 năm qua và là một công cụ hữu dụng để giảm thiểu chi phí, giảm thiểu rủi ro trong công tác tìm kiếm thăm dò dầu khí hiện nay. Một số nghiên cứu khảo sát địa hóa trầm tích nông được các nhà thầu thực hiện tại các lô hợp đồng dầu khí trên biển và thềm lục địa Việt Nam đều có kết quả tốt phục vụ cho công tác định hướng tìm kiếm thăm dò.
Bài báo giới thiệu kết quả ứng dụng nghiên cứu địa hóa trầm tích nông trong tìm kiếm thăm dò dầu khí trên biển và thềm lục địa Việt Nam.
Özellikli Gruplarda ve Kronik Sağlık Sorunu Olan Bireylerde Kontrasepsiyon
Authors: AVCI Nihal , MECDİ KAYDIRAK Meltem , GÜNGÖR İlkay 
Published: April 2021

Doğurganlığın düzenlenmesi ve aile planlaması kavramları birbiri yerine kullanılan oldukça kapsamlı kavramlardır. Doğurganlığın düzenlenmesi hizmeti; riskli ve istenmeyen gebeliklerin önlenmesinin yanı sıra gebelik planlayan çiftler için ovulasyon zamanının belirlenmesinde önemli rol oynar. Sağlık bakım profesyonelleri tarafından sunulan kaliteli, etkin ve sürekli doğurganlığın düzenlenmesi hizmeti; adolesanlar, postpartum dönemdeki kadınlar, perimenopozal dönemdeki kadınlar, engelli kadınlar, mülteci kadınlar, erkekler gibi özellikli gruplarda ve kronik sağlık sorunu olan bireylerde morbidite ve mortalite oranlarının en aza indirilmesinde önemli rol oynayan koruyucu bir sağlık hizmetidir. Kullanılan kontrasepsiyon yönteminin sürekliliği ve etkinliği bireye özgü sunulan danışmanlık hizmeti ile yakından ilişkilidir. Bu nedenle sağlık bakım profesyonelleri özellikli gruplara ve kronik sağlık sorunu olan bireylere özgü doğurganlığın düzenlenmesi hizmeti vermelidir.
Doğurganlığın düzenlenmesi yöntemleri ile ilgili birçok çalışma olmasına rağmen özellikli grupların ve kronik sağlık sorunu olan bireylerin kontraseptif yöntem seçimine dair yapılan çalışma sayısı sınırlıdır. Bu bağlamda özellikli gruplara ve kronik sağlık sorunu olan bireylere yönelik uygun kontraseptif yöntemin belirlenmesine ve bu bireylere verilecek danışmanlık hizmetine yönelik çalışmalara ihtiyaç vardır. Bu derlemede amaç özellikli gruplara ve kronik sağlık sorunu olan bireylere uygun kontraseptif yöntemleri irdelemek ve sağlık bakım profesyonellerine yönelik güncel bir kaynak oluşturmaktır.
Hubungan Frekuensi Perawatan Payudara dengan Kelancaran Produksi ASI pada Ibu Nifas Hari ke 4
Authors: Qiftiyah Mariyatul , Rahmawati Eva Silviana , Utami Aris Puji , Hurin’in Nur Maziyah 
Published: April 2021

Abstrak. ASI memberi semua energi dan nutrisi yang dibutuhkan bayi selama 6 bulan pertama hidup bayi, sehingga dianjurkan untuk enam bulan pertama bayi hanya diberi ASI Ekslusif tanpa tambahan makanan atau minuman lain. Penelitian ini bertujuan untuk menganalisa hubungan frekuensi perawatan payudara dengan kelancaran produksi ASI pada ibu nifas hari ke 4. Metode penelitian yang digunakanan adalah analitik observasional dengan pendekatan cross sectional. Populasi dalam penelitian adalah seluruh ibu nifas hari ke 4 di BPS Asri dan Polindes Permata Bunda Tuban bulan Juli - AgustusTahun 2020, sampel penelitian adalah sebagian ibu nifas hari ke 4 di BPS Asri dan Polindes Permata Bunda Tuban bulan Juli – Agustus Tahun 2020. Teknik sampling yang digunakan dalam penelitian ini adalah simple random sampling. Variabel independen dalam penelitian ini adalah frekuensi perawatan payudara sedangkan variabel dependen dalam penelitian ini kelancaran produksi ASI. Analisis data dalam penelitian menggunakan korelasi Spearman dengan batasan signifikan jika p-value < 0,05. Analisa hasil penelitian menunjukkan p-value = 0,000 yang berarti terdapat hubungan antara frekuensi perawatan payudara dengan kelancaran produksi asi pada ibu nifas hari ke 4. Pentingnya ASI bagi bayi maka ibu nifas diharapkan selalu menjaga kelancaran ASI dengan cara melakukan perawatan payudara secara rutin dan benar.
Kata kunci. Perawatan payudara, ASI, Nifas

The Correlation between The Frequency of Breast Care and The Smooth Production of Breast Milk on Day 4 Postpartum
Abtract.Breastmilk provides all the energy and butrition a baby needs for the first 6 months of baby life. The firts six months only exclusive breastfeeding is provided for babies without any additional food or drink. This study aims to analyze the correlation between the breast care frequency and the smooth production of breastmilk in post-partum mothers on day 4. The research method was observational analytic with a cross-sectional approach. The study population was all-day 4 postpartum mothers and the study sample were some of the fourth days' postpartum mothers at BPS Asri and Polindes Permata Bunda Tuban in March-April 2020. The research sampling was simple random sampling. The independent variable was the frequency of breast care, while the dependent variable was the milk production smoothness. Data analysis used the Spearman correlation with significant limits of p-value <0.05. The analysis of the results showed a p-value=0.000, which means that there was a correlation between the breast care frequency and the breastmilk smooth production in postpartum mothers on day 4. The importance of breastfeeding for babies is that postpartum mothers are expected to always maintain the smooth running of breast milk by doing regular and correct breast care.
Keywords. Breast care, breast milk, postpartum
Analisis Perilaku Percobaan Bunuh Diri pada Klien Skizofrenia dengan Pendekatan Model Adaptasi Roy: Studi Kasus
Authors: Budiarto Eka 
Published: April 2021

Abstrak. Bunuh diri merupakan respon maladaptif dari rentang respon protektif diri. Bunuh diri terjadi sebagai akibat dari stress dan depresi yang disebabkan faktor psikososial yaitu kepribadian, psikodinamika, kegagalan yang berulang, faktor kognitif, dukungan sosial, pengalaman masa lalu, dan stressor lingkungan. Model adaptasi Roy memandang manusia sebagai makhluk biopsikososial dan memiliki permasalahan yang menuntut manusia beradaptasi dengan masalah tersebut. Tujuan penulisan artikel ini adalah memperoleh penjelasan empiris dan teoris terhadap faktor psikososial kaitannya dengan perilaku resiko bunuh diri. Studi kasus ini menggunakan metode deskriptif pada kasus kelolaan di rumah sakit jiwa. Pengelolaan stress yang adapatif merupakan upaya preventif terhadap perilaku resiko bunuh diri. Perilaku bunuh diri tidak akan terjadi apabila individu dapat menggunakan mekanisme koping adaptif yang didukung oleh sosial support, hubungan interpersonal, dan kemampuan memilih strategi koping sebagai faktor protektor. Perawat dalam mengelola klien dengan riwayat bunuh diri harus melibatkan keluarga dan masyarakat untuk mengoptimalkan penggunaan faktor protektor tersebut. Kata kunci: Adaptasi Roy, Depresi, Perilaku Bunih Diri, Psikososial, Stress
Behavior Analysis of Suicide Experiment with Roy's Adaptation Model Approach:
Case study
Abstract. Suicide is a maladaptive response of a range of self-protective responses. Suicide occurs as a result of stress and depression caused by psychosocial factors such as personality, psychodynamics, repetitive failure, cognitive factors, social support, past experiences, and environmental stressors. Roy's adaptation model regards the humans as biopsychosocial beings and has problems that demand the humans to adapt the problem. The purpose of this article is to obtain the empirical and theoretical explanations of psychosocial factors related to suicidal risk behavior. This case study uses descriptive methods in cases of management in a mental hospital. Adapatif stress management is a preventive effort against suicidal risk behavior. Suicidal behavior will not occur if individuals can use adaptive coping mechanisms supported by social support, interpersonal relationships, and ability to choose coping strategies as a protector factor. Nurses in managing clients with a history of suicide should involve families and communities to optimize the use of these protector factors.
Keywords : Roy's adaptation, Suicide Risk, Depression, Stress, Psychosocial
Preparation and optimization of the composition of novel nZVI/(Fe-Mn) binary oxide/bentonite adsorbent for removal of reactive yellow 145 dye (RY-145) from aqueous solution
Authors: Pham Thi Thanh Huyen  , Nguyen Binh Duong  , Quan Thi Thu Trang  , Pham Van Lam  
Published: April 2021

In this study, a new composite of nZVI/(Fe - Mn) binary oxide/bentonite (IFMB) was synthesized and used as an adsorbent for the removal of reactive yellow 145 dye (RY- 145) from aqueous solution. Optimization of composition of IFMB composite for removal of RY - 145 dye was conducted with the help of surface response method (SRM). Three independent variables affecting to the RY-145 adsorption efficiency were selected for optimization study: Fe/Mn ratio (mol/mol), Bentonite content (wt. %) and nZVI content (wt. %). The study reveals that optimal compositions of IFMB composite for RY-145 removal was Fe/Mn = 1,75; Bentonite 9,46 wt. % and nZVI 16,97 wt. %. In the adsorption condition: adsorbent dose of 1g.L-1, initial dye concentration of 200 mg.L-1, contact time of 120 min at 120 rpm and at 25 oC, the adsorption capacity for RY-145 dye on IMFB composite is 197 mg.g-1. The value of RY-145 adsorption efficiency calculated by the model at the optimal point has been compared with the experimental value and the error is very small (0,36%). This proves that the RSM model has good repeatability.
Photocatalytic activities of NiFe2O4/nitrogen-doping graphene oxide synthesized by hydrothermal method
Authors: Nguyen Ngoc Minh  , Le Thi Cam Nhung  , Truong Cong Duc  , Nguyen Thi Lieu  , Nguyen Van Thang  , Dinh Quang Khieu  , Nguyen Thi Vuong Hoan  
Published: April 2021

The NiFe2O4/N-doped GO composites were successfully synthesized by the hydrothermal method from graphene oxide GO, urea, iron nitrat, and niken nitrat. GO was synthesized by a modifìied Hummers, method. The obtained composites exhibited photocatalytic activities for methylene blue degradation (MB) under visible light irradiation. MB photodegradation efficiency reaches 98% after 240 minutes of illumination. The NiFe2O4/N-doped GO (NF/GO-N) was of better photocatalytic than that of the NF and GO-N. A kinetic model was proposed by the combination of classical Langmuir-Hinshelwood kinetic model, the experimental data fit well the proposed model.
Fischer-Tropsch synthesis over Co/g-Al2O3 catalyst loaded on ceramic monolith-structured substrate
Authors: Do Pham Noa Uy  , Nguyen Manh Huan  , Hoang Van Loc  , Luc Minh Chien  , Nguyen Thi Chau Giang  , Truong Van Nhan  , Phan Minh Quoc Binh  , Nguyen Huu Luong  , Huynh Minh Thuan  
Published: April 2021

Cobalt-based catalyst supported on g-Al2O3­ was prepared by impregnation method and loaded on ceramic monolith-structured substrate by wash-coating slurry method. Physico-chemical properties of the catalysts were characterized by X-ray diffraction (XRD), Brunauer–Emmett–Teller (BET) specific surface area and H2 temperatured-programmed reduction (H2-TPR). Activity of the catalysts for Fischer-Tropsch synthesis was investigated in a tubular reactor in a temperature range of 200-275 oC at 20 bar and GHSV = 3000 h-1. Co/g-Al2O3 catalyst loaded on ceramic monolith-structured substrate enhanced efficacy of Fischer-Tropsch synthesis by increasing and stabilizing CO conversion and C5+ selectivity, compared to Co/g-Al2O3 powder catalyst.
Analisis Faktor Yang Mempengaruhi Belanja Daerah Kabupaten Sidoarjo Tahun Anggaran 2009 -2018
Authors: Pratama Bemby Agung 
Published: April 2021

Abstrak:
Penelitian ini bertujuan untuk menganalisis pengaruh Pertumbuhan Ekonomi,PAD dan DAU terhadap Belanja Daerah di Kabupaten Sidoarjo pada tahun 2009-2018. Penelitian ini merupakan penelitian kuantitatif dengan desain penelitian deskriptif dan Asosiatif.Data yang digunakan yaitu data time series PAD, dana perimbangan, dan belanja daerah pada website DJP Kemenkeu dan Badan Pusat Statistik (BPS) Kabupaten Sidoarjo tahun 2009-2018. Teknik pengumpulan data yaitu secara sekunder dengan mengumpulkan beberapa refrensi dari website DJP Kemenkeu dan BPS Sidoarjo.Teknik analisis data menggunakan statistika deskriptif, uji asumsi klasik, uji korelasi sederhana dan berganda, uji regresi dan uji hipotesis parsial (uji t) dan uji hipotesis simultan (uji F) dengan bantuan software SPSS.Hasil analisis menunjukkan secara uji (t) parsial Dana Alokasi Umum(DAU) berpengaruh signifikan terhadap belanja daerah,sedangkan pertumbuhan ekonomi dan Pendapatan Asli Daerah (PAD) tidak berpengarauh secara signifikan terhadap belanja daerah. Secara uji (f) simultan pertumbuhan ekonomi,pendapatan asli daerah (PAD) dan dana alokasi umum (DAU) berpengaruh signifikan terhadap belanja daerah.
Pengaruh Kualitas Pelayanan Dan Keputusan Terhadap Loyalitas Pelanggan
Authors: Azrullah Muhammad Mashudi 
Published: April 2021

The focus of this research is the influence of service quality and satisfaction on customer loyalty with a case study in “Café : Kofi” Bangil. This research method is quantitative, the subject of this study are customers of “Café : Kofi” Bangil. The sampling technique used was purposive sampling. With a total of 60 respondents. The result show multiple liniear regression test Y + 0,180 + 0,041 + 0,941 + e. shows that the influence of service quality variables is 0,041 an the effect of satisfaction variables is 0,941. Thus the more dominant variable influencing customer loyalty is the satisfaction variable. T-test results indicate that the service quality variable (X1) has no partial effect and is not significant. While the satisfaction variable is partially significant. Test the coefficient of determination R2 obtained 0,899 or 89,9% this means that customer loyalty is influenced by satisfaction variables.
Keywords : Quality Of Service, Satisfaction
Pengaruh Model Kepemimpinan dan Motivasi Kerja Terhadap Kinerja Pegawai Aparatur Sipil Negara
Authors: Mutohar Achmad 
Published: April 2021

The focus of this research is the influence of leadership models and work motivation on the performance of civil servants in the state. This research was conducted at the Sukomanunggal office, Surabaya, East Java. The research was conducted from May to July 2019. The type of research was primary data using a questionnaire. The population in this study includes 30 civil servants of the Sukomanunggal sub-district, Surabaya, who are also the sample in this study. The result shows that partially the leadership model variable and the work motivation variable have a significant effect on employee performance, and simultaneously the independent variable also has a significant effect on the dependent variable with a sig of 0,000. With multiple linear regression analysis Y = 0,531 + 0,375X1 + 0,454X2 + 2. As well as the coefficient of determination of 55,7%, while the remaining 44,3% is influenced by other factors outside the X variable used.
Keywords: Leadership Model, Work motivation, Employee Performance
A review on preclinical studies conducted with Homeopathic medicine Cephalandra indica as an Anti-hyperglycemic agent
Authors: Wakte Dr. Mitesh Santosh , Patil Aditya Dilipkumar 
Published: April 2021

Background –
Diabetes Mellitus a metabolic disorder affects the secretion of insulin from pancreas leading to hyperglycemia, if uncontrolled leads to complications triggered by free radical formed after oxidative stress. Homeopathic medicine Cephalandra Indica has shown antidiabetic activity in various potencies performed on preclinical studies on diabetic rat model. The present review highlights the pharmacological profile of homeopathic preparations Cephalandra Indica on preclinical studies and calculating the probable human equivalent dosage from preclinical studies for the pilot studies.
Method –
Articles published between January 1988 and December 2018 was included in review. Databases like PubMed – Medline, Google scholar were used for collecting the articles. Keywords like ‘Homeopathy’ or ‘Homoeopathy’, ‘Invitro’, ‘Invivo’ and ‘Cephalandra Indica’ were used. SABEH criteria were implemented for assessing methodology quality of articles.
Results –
Seven full text articles were included in review which had six Invivo studies and one Invitro study. This review article provided the scientific validation of high diluted homeopathic medicines pharmacological activity of Cephalandra Indica and probable mechanism of action confirmed through preclinical studies. Conversion of dosage from animal model to human dosage for pilot studies has been hypothetically proposed.
Conclusion –
Homeopathic medicine Cephalandra Indica has a therapeutic and safety profile with no toxicity observed in preclinical studies. The proposed hypothesis of conversion of dosage needs to be validated for further studies.