bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gender Differences in Symptom Presentation and Treatment Outcome in Children and Youths With Eating Disorders
Authors: Coelho Jennifer S. , Suen Janet , Marshall Sheila , Burns Alex , Geller Josie , Lam Pei-Yoong 
Published: July 2021

Abstract
Background. To address the gaps in the literature examining eating disorders among males and gender minority youths, a prospective study was designed to assess gender differences in eating disorder symptom presentation and outcomes. Muscularity concerns may be particularly relevant for male youths with eating disorders, and were included in assessment of eating disorder symptom presentation. Methods. All male youths who presented for specialized eating disorder treatment at one of two sites were invited to participate, along with a group of matched females, and all youths who did not identify with the sex assigned to them at birth. Youths completed measures of eating disorder symptoms, including muscularity concerns, and other psychiatric symptoms at baseline and end of treatment.Results. A total of 27 males, 28 females and 6 trans youths took part in the study. At baseline, Kruskal-Wallis tests demonstrated that trans youths reported higher scores than cisgender male and female youths on measures of eating pathology (Eating Disorder Examination – Questionnaire (EDE-Q) and the body fat subscale of the Male Body Attitudes Scale (MBAS)). These analyses demonstrated that there were no differences between cisgender male and female youths on eating disorder symptoms at baseline. However, repeated measures ANOVA demonstrated that males had greater decreases than did females in eating pathology at discharge than did females, based on self-reported scores on the EDE-Q, MBAS, and Body Change Inventory. Conclusions. Gender differences in eating pathology appeared at baseline, with trans youths reporting higher levels of eating pathology than cisgender youths, though no differences between cisgender males and females emerged at baseline for eating disorder symptom presentation. Contrary to expectations, there were no gender differences in measures of muscularity concerns. Males demonstrated greater eating disorder symptom improvements than females, suggesting that male adolescents may have better treatment outcomes than females in some domains.
Cross-Modal Environment Self-Adaptation During Object Recognition in Artificial Cognitive Systems
Authors: Miralles David , Garrofé Guillem , Parés Calota , González Alejandro , Serra Gerard , Soto Alberto , de Beeck Hans Op , Masson Haemy Lee , Sevillano Xavier 
Published: July 2021

Abstract
The cognitive connection between the senses of touch and vision is probably the best-known case of cross-modality. Recent discoveries suggest that the mapping between both senses is learned rather than innate. These evidences open the door to a dynamic cross-modality that allows individuals to adaptively develop within their environment. Mimicking this aspect of human learning, we propose a new cross-modal mechanism that allows artificial cognitive systems (ACS) to adapt quickly to unforeseen perceptual anomalies generated by the environment or by the system itself. In this context, visual recognition systems have advanced remarkably in recent years thanks to the creation of large-scale datasets together with the advent of deep learning algorithms. However, such advances have not occurred on the haptic mode, mainly due to the lack of two-handed dexterous datasets that allow learning systems to process the tactile information of human object exploration. This data imbalance limits the creation of synchronized multimodal datasets that would enable the development of cross-modality in ACS during object exploration. In this work, we use a multimodal dataset recently generated from tactile sensors placed on a collection of objects that capture haptic data from human manipulation, together with the corresponding visual counterpart. Using this data, we create a cross-modal learning transfer mechanism capable of detecting both sudden and permanent anomalies in the visual channel and still maintain visual object recognition performance by retraining the visual mode for a few minutes using haptic information. Here we show the importance of cross-modality in perceptual awareness and its ecological capabilities to self-adapt to different environments.
Right Ventricular Free Wall Strain for Detection of Anthracycline Induced Cardiac Toxicity
Authors: Attar Armin , Azizi Fatemeh , Abtahi Firoozeh , Karimi Mojtaba 
Published: July 2021

Abstract
Background
Anthracycline agents are routinely used for treatment of many types of malignancy, while imposing the risk for cardiotoxicity (AT-CMP). Although the right ventricle (RV) is more susceptible to cardiotoxicity, most of the studies have focused on left ventricle (LV) function for monitoring AT-CMP. In this study, we have focused on RV function before and after chemotherapy using two-dimensional speckle tracking Echocardiography (2D-STE).
Material and Methods
In this prospective study, newly diagnosed and untreated cancerous patients without previous cardiovascular diseases were enrolled. For all patients, baseline echocardiography was performed before the initiation of the anthracycline regimen and after 6 months of follow up when the chemotherapy was stopped. Several parameters of LV and RV function were measured using 3D echocardiography and STE techniques.
Results
60 patients were enrolled in the study. There was a significant decrease (P = 0.001) in RV fractional area change (53.57 %±4.36 vs. 45.66% ±6.19), RV Global longitudinal strain (GLS) (− 22.93%±1.95 vs. −18.53 ± 2.75), and RV free wall strain (FWLS) (− 25.75%±3.01 VS. −20.30 ± 3.78). There was a significant decline in LVEF (59.42 ± 6.36% vs. 51.1 ± 6.31%) and LV-GLS (-21.1 ± 1.8% vs -18.6 ± 2.6%) (both P = 0.001) as well. Among the parameters changed following chemotherapy, RV-FWLS was dropped to a pathological level in 25% of patients showing the highest potential for detection of anthracyclines effect on the myocardium.
Conclusion
Anthracycline therapy can induce subclinical RV dysfunction. RV-FWLS may be proposed as the most sensitive echocardiographic marker for monitoring AT-CMP. This finding needs to be confirmed in future and larger studies.
Dyslipidemia Associates with Respiratory Resistance Assessed by Forced Oscillation Technique in Asthmatic Children
Authors: Chanachon Pakvirin Nanakorn , Kanchongkittiphon Watcharoot , Jotikasthira Wanlapa , Kiewngam Potjanee , Sawatchai Adithep , Manuyakorn Wiparat 
Published: July 2021

Abstract
Purpose: This study evaluated the correlation between dyslipidemia and pulmonary function parameters assessed by spirometry and force oscillation technique in asthmatic children.Methods: Asthmatic children (aged 5–18 years old) were measured for fasting serum lipid profiles, including low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C) and C-reactive protein (CRP). Pulmonary function tests were assessed by spirometry and forced oscillation technique (FOT). Results: One hundred forty-one asthmatic children were enrolled with the mean (sd) age of 11.82 (3.38) years. Eighty-eight children (62.4%) were males, 64 children (45.4%) had dyslipidemia, and 20 (14.2 %) children were obese. Of 64 children with dyslipidemia, high LDL-C was the most common dyslipidemia (65.6%), followed by TC (57.8%), non-HDL-C (53.1%), TG (35.9%), and low HDL-C (15.6%). There were no significant differences in spirometry parameters and FOT parameters between asthmatic children who had dyslipidemia and normal lipid levels. Asthmatic children who had high LDL-C had significantly higher expiratory phase respiratory resistance at 5 Hz (R5), whole breath R20 and expiratory phase R20 evaluated by FOT than those with normal LDL-C (p < 0.05). There were no significant differences in weight, height, obesity status, and CRP level between children with high and normal LDL-C. Conclusion: The prevalence of dyslipidemia in children with asthma is high. LDL-C is associated with more elevated respiratory resistance assessed by FOT in asthmatic children. Intervention lowering LDL-C may have a benefit on lung function in asthmatic children.
3D Hotspot Matrix of Au Nanoparticles on Au Nanostructures with a Spacer Layer of Dithiol Molecules for Highly Sensitive Surface-Enhanced Raman Spectroscopy
Authors: Lee Dong-Jin , Kim Dae Yu 
Published: July 2021

Abstract
Engineering of efficient plasmonic hotspots has been receiving great attention to enhance the sensitivity of surface-enhanced Raman scattering (SERS). In the present study, we propose a highly sensitive SERS platform based on Au nanoparticles (AuNPs) on Au nanostructures (AuNSs) with a spacer layer of 1,4-benzenedimethanethiol (BDMT). The three-dimensional (3D) hotspot matrix has been rationally designed based on the idea of employing 3D hotspots with a vertical nanogap between AuNSs and AuNPs after generating large area two-dimensional hotspots of AuNSs. AuNP@BDMT@AuNSs are fabricated by functionalizing BDMT on AuNSs and then immobilizing AuNPs. The Raman signal of the AuNP@BDMT@AuNSs is approximately twelve times higher than that of AuNSs at 100 nM of rhodamine 6G. The AuNP@BDMT@AuNSs are then employed to detect thiram, which is used as a fungicide, with a detection limit of 13 nM. Our proposed platform thus shows significant potential for use in highly sensitive SERS sensors.
Effect of Electron and X-ray Irradiation on Microbiological and Chemical Parameters of Chilled Turkey
Authors: Bliznyuk Ulyana , Ananiev Vasily , Avdyukhina Valentina , Borshegovskaya Polina , Bolotnik Timofey , Ipatova Victoria , Ihalainen Yuri , Nikitina Zoya , Nikitchenko Alexander , Rodin Igor , Studenikin Felix , Khmelevskiy Oleg , Chernyaev Alexander , Shinkarev Oleg , Yurov Dmitry 
Published: July 2021

Abstract
The purpose of this work was to compare the effect of electron and X-ray irradiation on microbiological content and volatile organic compounds in chilled turkey meat. Dose ranges which significantly suppress the pathogenic microflora while maintaining the organoleptic properties of the turkey meat are different for electron and X-ray irradiation. According to the study it is recommended to treat chilled turkey using X-ray irradiation with the dose ranging from 0.5 kGy to 0.75 kGy, while in electron irradiation permissible doses should be within 0.25 kGy-1 kGy. Three main groups of volatile compounds: alcohols, ketones, and aldehydes were found in irradiated and non-irradiated samples of turkey meat. It was found that the total amount of aldehydes, which are responsible for the formation of a specific odor of irradiated meat products, increases exponentially with the increase in the absorbed dose for both types of irradiation. It was established that acetone can be used as a potential marker of the fact of exposure of low-fat meat products to ionizing radiation.
Accessing and Engaging with Antenatal Care: An Interview Study of Teenage Women
Authors: Shee Anna Wong , Frawley Natasha , Robertson Carolyn , McKenzie Anne Marie , Lodge Julie , Versace Vincent , Nagle Cate 
Published: July 2021

Abstract
BackgroundPregnant teenagers in rural and regional areas experience distinct disadvantages, that are not simply a function of their age, and these have a substantial impact on their health and that of their baby. Studies demonstrate that antenatal care improves pregnancy outcomes amongst pregnant women, especially adolescents. Understanding teenager’s views and experiences of pregnancy and motherhood is important to ensure antenatal care meets young women’s needs. This study explored teenage women’s experiences and perceptions of barriers and facilitators to engaging in pregnancy care in rural and regional Victoria, Australia.MethodsBetween February - October 2017, semi structured interviews were conducted with pregnant women aged ≤ 19 years from rural and regional areas. Interviews were audio-taped, professionally transcribed and thematic analysis undertaken.ResultsFour key themes emerged from the analysis of the transcripts of 16 interviews: Valuing pregnancy care, Interactions with Maternity Service, Woman-centred care, and Support systems. Teenage women primary motivation to attend care was to ensure their baby’s wellbeing and lack of engagement occurred when the relevance of antenatal care was not understood. Appointment flexibility and an accessible location was important; most participants were reliant on others for transport. Continuity of carer and respectful, non-judgement communication by staff was highly valued. Many young women had fractured families with pregnancy diminishing their social world, yet having a baby gave them purpose in their lives.ConclusionMaternity services and health professionals that provide flexible, adaptable women-centred care and support through pregnancy and early motherhood will assist young women’s engagement in antenatal care.
TMUB1 as a diagnostic and prognostic marker for colorectal cancer
Authors: Hao Tao , Liu Qian , Lv Xin , Qiu Jun , Zhang Haoran , Jiang Hai-Ping 
Published: July 2021

Abstract
BackgroundTransmembrane and ubiquitin-like domain-containing protein 1 (TMUB1) is overexpressed in a large number of liver and esophageal tumors. However, only a few reports on the clinical significance of TMUB1 in colorectal cancer (CRC) exist. MethodsHere, we evaluated the clinical significance and potential biological role of TMUB1 using bioinformatics analysis. Univariate and multivariate analyses were performed to evaluate the relationship of TMUB1 with clinicopathological features. Gene set enrichment analysis (GSEA) was performed to identify the biological function of TMUB1, while any associations between the expression of TMUB1 and the infiltration of 24 immune cells were analyzed using imple-sample GSEA. ResultsTMUB1 was significantly overexpressed in CRC tissues compared with normal controls. High expression of TMUB1 in CRC was associated with T stage, neotype, and residual tumor. Moreover, TMUB1 was identified as an independent factor of poor disease-free survival (DFS) and short overall survival (OS). GSEA demonstrated that TMUB1 was related to hypoxia, angiogenesis, adipogenesis, inflammatory response, IL6-JAK-STAT3 signaling, apoptosis, mitotic spindle, and IL2-STAT5 signaling. The expression of TMUB1 negatively correlated with the abundance of T helper cells, Tcm cells, macrophages, and Th2 cells, whereas it positively correlated with the abundance of several immune cell types, including CD56bright and CD56dim NK cells. ConclusionsTMUB1 may be a potential diagnostic and prognosis biomarker for colorectal cancer
Distribution of risks and Factors Associated with Unscreened Hypertension among Adults Living in Rural of Dano District, West Shewa, Oromia, Ethiopia, 2020: Community-based cross-sectional study
Authors: Regea Firaol 
Published: July 2021

Abstract
Background: Hypertension affects more than one quarter of adults worldwide and one in three peoples in developing countries. Although Hypertension is known to be a silent medical condition, there is limited information on the prevalence of unscreened hypertension and associated factors among rural dwellers in Ethiopia in general and Dano district in particular. Objective: To assess the prevalence of Unscreened hypertension and associated factors among adults living in the rural area of Dano district, West Shewa, Oromia, Ethiopia 2020.Methods and materials - A community-based cross-sectional study was employed. A multi-stage sampling technique was used to select 605 Adults from the rural community of Dano District from May 23 -July 5, 2020. Data were collected by trained BSc nurses and Public health officers. Standardized WHO STEPS survey tool was used to collect socio-demographic and behavioral characteristics of the participants. Standardized digital blood pressure device was used to measure Blood pressure. The mean score of three blood measurements was used to classify hypertension after intra-class correlation was tested. GmateTM blood glucose measuring device was used to measure blood sugar. Multivariable logistic regression analysis was done to identify factors independently associated with unscreened hypertension. Adjusted Odds Ratio with 95% CI was estimated to measure the strength of association. The level of statistical significance was declared at p-value < 0.05. The results presented by tables and figures. Result: The prevalence of Unscreened Hypertension was 14.6%, (95% CI: 11.95%, 17.4%). Being in age of 19-33 years[(AOR: 2.5,95%CI:( 1,6)], having family history of hypertension [AOR=3.1,95%CI:(1.23,7.77)],having other chronic disease [AOR=0.28,95%CI:(0.11, 0.72)], Participants’ health-seeking behaviour to hypertension[AOR=3.3,95%CI:(1.6,6.5)] and participants knowledge about hypertension[AOR=2.3,95%CI:(1.2,4.5)]were independently associated with unscreened Hypertension.Conclusion - The evidence from this study shows unscreened hypertension is prevalent among adults in the study area. Therefore, opportunistic screening of adults regardless of their age and health status is important.
Common laboratory mice are susceptible to infection with SARS-CoV2 beta variant
Authors: Kant Ravi , Kareinen Lauri , Smura Teemu , Freitag Tobias L. , Jha Sawan Kumar , Alitalo Kari , Meri Seppo , Sironen Tarja , Saksela Kalle , Strandin Tomas , Kipar Anja , Vapalahti Olli 
Published: July 2021

Abstract
Small animal models are of crucial importance for assessing COVID-19 countermeasures. Common laboratory mice would be well-suited for this purpose but are not susceptible to infection with wild-type SARS-CoV-2. Herein we show that the SARS-CoV-2 beta variant attains infectibility to BALB/c mice and causes pulmonary changes consistent with COVID-19.
Chronic lymphocytic leukemia; an incidental finding in a COVID-19 patient.
Authors: Sidhu Shazaf Masood , Muhammad Fabiha Ghulam , Arshad Ainan 
Published: July 2021

Abstract
We report a case of 57 years old male, with no prior comorbids functional class I, presented with a history of fever for one week along with shortness of breath and cough for 5 days. Upon workup his baseline CBC reported bicytopenia along with marked lymphocytosis which raised the suspicion and to confirm the diagnosis, his acute leukemia comprehensive panel was done which reported an incidental finding of Chronic lymphocytic leukemia along with concomitant COVID PCR positive. This patient also presented with Tumor Lysis Syndrome and Acute kidney Injury.
Severe azotemia in a young breeding ram following to acute urethral obstruction by throughout intra-luminal blood clots
Authors: Alidadi Nasser , Moradikia Mohammadhossein , Mohammaddavoodi Hesaam 
Published: July 2021

Abstract
Urethral obstruction is a very important problem in small ruminants` flocks, as it affects breeding rams and so invaluable genetic reserves of the population. A three-years-old breeding ram referred to the teaching hospital with the owner`s compliant of lack of urination in previous two days. The ram was the only one in the flock which it had unlimited access to fat-tailed ewes. The other signs consisted of anorexia, reluctance to walking and final lateral recumbency. Severe depression, anuria, dribbling of blood drops from the glans and firmness of the enlarged penis in palpation were detected in the clinical examination. But noticeably there was no local subcutaneous edema and even swelling outside of the penis as it could be usually observed in urolithiasis. It was noticeable that the animal had remarkable bleeding tendency. An obvious splashing sound was heard using stethoscope auscultation on the right flank along. Abdominal paracentesis demonstrated a blood-tinged peritoneal fluid. Ultrasonography showed a completely distended urinary bladder. The animal died because of severe obstructive azotemia. The distended urinary bladder was opened and large amounts of blood-tinged urine flashed out. The urethra was incised but no urinary stones were detected in the lumen. Otherwise, an intra-luminal blood clotting at full length was detected following to the proximal internal hemorrhage. Obviously, this complex case may be confused with urolithiasis and should be exactly differentiated. There is no available reported data concerning the entity in literature. This case report is discussing the matter.
Identifications of multi-drug resistanturopathogens among infected patients from hospitals in Nablus-Palestine
Authors: Menawi Wafaa , Athamny Tamador , Khodair Lama , Mansour Haya , Shehadeh Mayce , Deen Rahaf Zain Al , Zaid Lama 
Published: July 2021

Abstract
Urinary tract infection UTI is the most common bacterial infection in the human population, and is considered to be a common cause of death all over the world. The increase in resistance in many bacterial strains prompted the researchers to do studies on it as well. This research aims to investigate the multi-drug resistant uropathogens among patients taking their care in Rafidia and Al Watani Hospitals and Patients Friends Society (Mostawsaf Al-Rahma) in Nablus-Palestine using the skills and knowledge that we have acquired during study at ANNU to apply it in our graduating project from January to July 2021 in Nablus, Palestine. 100 urine samples from UTI infected patients have been randomly selected from the medical laboratories related to health care facilities mentioned above after the approval of IRP and the directorate of Health Education. The bacterial species have been identified then their multidrug resistant activity has been investigated against several numbers of antibiotics. E.coli was the most frequent bacteria presented in the urine samples 39%, followed by S.epidermidis, Enterococcus, K.pneumoniae, and Pseudomonas respectively. Frome the gram-positive group 4 samples were resistante to the entire antibiotics being used, and in general the samples showed the highest resistance for ampicillin, followed by amikacin, ciprofloxacin, Gentamicin, Imipenem. From the gram-negative group 2 samples were resistante to the 5 antibiotics being used, and generally the samples showed the highest resistance for ciprofloxacin, followed by ceftazidime, gentamicin, imipenem, amikacin.
Macro- and microelements in some species of marine life from the Sea of Okhotsk
Authors: Stepanova Evgenia , Lugovaya Elena 
Published: July 2021

Introduction. Residents of northern regions have a diet low in essential macro- and microelements. The Sea of Okhotsk is an enormous source of fish and non-fish products. We aimed to determine mineral contents in marine fish, shellfish, and algae in order to assess if they could satisfy the daily requirement for these elements through fish and non-fish consumption.
Study objects and methods. Our study objects were saffron cod (Eleginus gracilis L.), blue-headed halibut (Reinhardtius hippoglossoides L.), commander squid (Berryteuthis magister L.), northern shrimp (Pandalus borealis L.), salted pink salmon caviar (Oncorhynchus gorbuscham L.), and kelp (Laminaria L.). The contents of 25 macro- and microelements were determined by atomic emission spectrometry and mass spectrometry with inductively coupled argon plasma.
Results and discussion. The absolute contents of macro- and microelements in the marine species were used to assess the proportion of the recommended daily requirement that they account for. Also, we performed a thorough comparative analysis of mineral quantities in the studied species of marine fish, pink salmon caviar, shellfish, and algae from the Sea of Okhotsk. Finally, we examined the elemental status of the coastal residents belonging to the “northern type” and identified their deficiencies of vital chemical elements.
Conclusion. Some chemical elements in the studied marine species from the Sea of Okhotsk (Magadan Region) satisfy over 100% of the daily human requirement for these minerals. Therefore, their products can be recommended as part of a northern diet in order to compensate for the deficiencies of certain minerals.