bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differentiating stages of reward responsiveness: Neurophysiological measures and associations with facets of the behavioral activation system
Authors: Pegg Samantha , Jeong Hee Jung , Foti Dan , Kujawa Autumn 
Published: January 2021

AbstractThe Research Domain Criteria (RDoC) positive valence systems domain include multiple aspects of reward responsiveness with potential to elucidate the understanding of motivational and hedonic deficits in psychological disorders. There is a need for reliable and valid methods to delineate behavioral and biological processes underlying stages of reward responsiveness. Event‐related potentials (ERPs) offer a promising method for examining the temporal dynamics of reward processing, but the literature has mainly focused on the feedback stage and often single components. We investigated the electrophysiological aspects of reward anticipation and initial response to reward using an ERP monetary incentive delay task in 114 emerging adults. Principal component analysis was used to derive temporally and spatially distinct ERP components sensitive to reward processing. Components that reflect initial engagement toward a cue indicating potential reward (cue‐P3) and anticipation of possible reward feedback (stimulus‐preceding negativity; SPN) emerged in the anticipatory stage. In the initial response to reward stage, a reward positivity (RewP) was found. We further tested the association between ERPs and self‐reported facets of the behavioral activation system. Greater self‐reported reward responsiveness was associated with heightened response in the anticipatory stage (i.e., cue‐P3, SPN). Self‐reported drive was positively associated with RewP, but fun‐seeking was negatively associated with RewP. Additional components were observed beyond those identified in prior work, warranting future research on temporal dynamics of reward processing across stages. Furthermore, examination of a broader range of reward‐related ERPs in clinical populations has the potential to more precisely characterize alterations in positive valence systems in psychopathology.
Blame Attribution Asymmetry in Human–Automation Cooperation
Authors: Liu Peng , Du Yong 
Published: January 2021

AbstractHuman–automation cooperation has become ubiquitous. In this concept, automation refers to autonomous machines, robots, artificial intelligence, and other autonomous nonhuman agents. A human driver will share control of semiautonomous vehicles (semi‐AVs) with an automated system and thus share responsibility for crashes caused by semi‐AVs. Research has not clarified whether and why people would attribute different levels of blame and responsibility to automation (and its creators) and its human counterpart when each causes an equivalent crash. We conducted four experiments in two studies (total N = 1,045) to measure different responses (e.g., severity and acceptability judgment, blame and responsibility attribution, compensation judgment) to hypothetical crashes that are caused by the human or the automation in semi‐AVs. The results provided previously unidentified evidence of a bias, which we called the “blame attribution asymmetry,” a tendency that people will judge the automation‐caused crash more harshly, ascribe more blame and responsibility to automation and its creators, and think the victim in this crash should be compensated more. This asymmetry arises in part because of the higher negative affect triggered by the automation‐caused crash. This bias has a direct policy implication: a policy allowing “not‐safe enough” semi‐AVs on roads could backfire, because these AVs will lead to many traffic crashes, which might in turn produce greater psychological costs and deter more people from adopting them. Other theoretical and policy implications of our findings were also discussed.
Oral health status and oral health‐related quality of life in children with attention‐deficit hyperactivity disorder and oppositional defiant disorder
Authors: Jamali Zahra , Ghaffari Parisa , Aminabadi Naser Asl , Norouzi Sanaz , Shirazi Sajjad 
Published: January 2021

AbstractAimsOral diseases can affect various aspects of life in patients with attention deficit hyperactivity disorder/oppositional defiant disorder (ADHD/ODD). This study aimed to assess the oral health status and oral health‐related quality of life (OHRQOL) in ADHD/ODD children.MethodsForty ADHD/ODD and 80 control children aged 3‐7 years old were included in the study. Gingival index (GI), dmft score, and the pediatric oral health‐related quality of life (POQL) questionnaire were used to determine the oral health status and OHRQOL, respectively.ResultsThe mean dmft and GI were significantly higher in the ADHD/ODD group than the control group (P = .002 andP = .001). In the ADHD/ODD children, the total score of OHRQOL and the mean scores of the emotional, physical, role, and social domains were lower than that in the control group (P = .0004,P = .027,P = .002,P = .014, andP = .043, respectively). Poisson's regression showed that there was a significant relationship between OHRQOL and dmft scores (P‐value < .001). However, the association between GI and OHRQOL scores was not significant.ConclusionHigher dmft and GI scores were found in children with ADHD/ODD than the control children. A lower POQL score was detected in ADHD/ODD patients, which translates to a better level of OHRQOL.
The Color of Electoral Success: Estimating the Effect of Skin Tone on Winning Elections in Mexico
Authors: Campos‐Vazquez Raymundo M. , Rivas‐Herrera Carolina 
Published: January 2021

ObjectiveEvidence suggests that voters’ prejudices may lead them to take information shortcuts in choosing political leaders. This study analyzes whether the skin tone of 12,798 candidates influenced the outcome of their electoral campaigns.MethodsTo determine the probability of winning an election, we estimate a linear regression where skin tone is used as an explanatory variable, with controls such as sex and political party. Based on the number of votes obtained by each candidate, we estimate an ordered logit model.ResultsCandidates with dark brown skin tones face a probability of winning that is 20–38 percent less than those with intermediate skin color. A one standard deviation increase in skin tone is associated with an 8 percent decrease in the probability of finishing in first place.ConclusionSkin color influences electoral outcomes. Public policies should therefore ensure equal access and true representativeness.
Disseminated Legionella micdadei infection in a liver transplant patient presenting as pulmonary nodules and a laryngeal lesion
Authors: Bond Allison R. , Bainbridge Emma , Doernberg Sarah B. , Babik Jennifer M. , Miller Steve , Khanafshar Elham , Henry Travis , David Abel , Russell Matthew , Brandman Danielle , Sherman Courtney B. , Yao Francis , Fung Monica 
Published: January 2021

AbstractWe report a liver transplant patient with disseminated Legionella micdadei infection with pulmonary, laryngeal, and suspected muscle involvement. This organism, which stains weakly acid‐fast, primarily affects immunocompromised patients. The diagnosis is difficult to make; in this case, the organism was identified via molecular diagnostics on laryngeal and pulmonary biopsy tissue.
Malaria and encephalopathy in a heart transplant recipient: A case report in the context of multiorgan donation
Authors: Vernaza Armando , Pinilla‐Monsalve Gabriel , Cañas Felipe , Carrillo Diana , David López Juan , Flórez Noel , Gomez‐Mesa Juan Esteban 
Published: January 2021

AbstractIntroductionMalaria is an endemic infection in tropical circles. It can be transmitted from mosquitoes bite, but exceptional cases have been attributed to multiorgan transplantation.Case reportThis is a 34‐year‐old woman who received a heart transplant for final‐stage dilated cardiomyopathy. Over the hospitalization, she developed fever, cephalalgia, and tonic‐clonic seizures with MRI findings compatible with posterior reversible encephalopathy. A thick blood smear revealed hemoparasitic forms of Plasmodium vivax. Afterward, malaria was also diagnosed in recipients of one kidney and liver of the same organ donor. First‐line treatment with artesunate was prescribed for 3 days and chloroquine with primaquine thereafter for 14 days. The patient was discharged and returned to the emergency department 5 days later, complaining of gastrointestinal symptoms and developed multiorgan failure that led to death.ConclusionWe report a case of malaria transmission through heart transplantation. Despite adequate and supervised treatment, it can be related to a fatal outcome. Malaria screening in organ donors should be considered in regions where endemicity can lead to rare cases of transmission by transplantation.
Divergence in phenotyping and genotyping analysis of the Lewis histo‐blood group system
Authors: Donta Ajaykumar , Gorakshakar Ajit C. , Ghosh Kanjaksha 
Published: January 2021

AbstractObjectivesThis study evaluated the red blood cell (RBC) Lewis phenotypes by simple haemagglutination technique and molecular genotyping in healthy individuals.BackgroundThe expression of Lewis antigen on RBCs is dependent on the interaction of FUT3 and FUT2 genes. Complexity of the genetic control of Lewis antigen expression and the error‐prone nature of Lewis phenotyping result in non‐genuine RBC Lewis phenotypes, which could be misleading.Materials and MethodsABO blood group and RBC Lewis phenotypes were determined by conventional haemagglutination tube techniques. FUT2 and FUT3 genotypes were analysed by polymerase chain reaction and direct DNA sequencing. The RBC Lewis phenotypes were also inferred from the FUT2 and FUT3 genotyping results.ResultsThe frequencies of RBC Lewis phenotypes typed by the conventional tube test were Le(a+b−) 19.63%, Le(a−b+) 49.32% and Le(a−b−) 31.05%, whereas the frequencies inferred from the FUT2 and FUT3 genotypes were Le(a+b−) 20.09%, Le(a−b+), 59.82%; Le(a−b−), 17.81%; and Le(a+b+), 5 (2.28%). The Le(a+b+) phenotype was not detected by the tube test, and a significant difference was observed in the frequencies of the determined Le(a−b−) and Le(a−b+) phenotypes.ConclusionThe phenotyping and genotyping of Lewis blood group system reveal a high rate of discordance in the frequencies of Lewis phenotypes among the healthy individuals.
Small‐scale field evaluation of the entomological efficacy and the residual activity of Fludora®Fusion WP‐SB indoor residual spraying againstAnopheles culicifacies s.l. in Gujarat, India
Authors: Kamaraju Raghavendra , Pant Chandra Shekhar , Uragayala Sreehari , Baharia Rajendra Kumar , Srivastava Harish Chandra , Yadav Rajpal S. 
Published: January 2021

AbstractObjectivesTo evaluate the entomological efficacy and the residual activity of indoor residual spraying with Fludora®Fusion 562.5 WP‐SB, a combination formulation containing clothianidin, a neonicotinoid and deltamethrin, a pyrethroid, against the main rural malaria vector,Anopheles culicifacies s.l., in India in a small‐scale trial.MethodsIn three study villages, suitable households were randomly allocated to five treatments: Fludora®Fusion 562.5 WP‐SB (target dose 225 mg active ingredient AI/m2); clothianidin 70 WG (target dose 200 mg AI/m2); K‐Othrine 250 WG (deltamethrin, target dose 25 mg AI/m2); Ficam VC 80 WP‐SB (bendiocarb, target dose 400 mg AI/m2) and unsprayed control. Insecticides were sprayed by hand compression sprayers with control flow valves and 8002E nozzles. Post‐spray cone bioassays were done on insecticide‐treated walls using a colonised, deltamethrin‐resistant strain ofAn. culicifacies. Mosquitoes were collected from treated rooms by different methods. The insecticide content on filter papers collected from the sprayed walls was determined by chemical assay to assess the spray quality.ResultsThe ratios of applied to target doses of insecticides were within 0.84 to 1.4, showing a good spray quality. The cone bioassays revealed residual action lasting 7 months for all insecticides without significant differences in mortality between different surfaces treated nor between the four treatment arms (P > 0.05). Considering all entomological parameters such as indoor resting density, excito‐repellency, blood‐feeding inhibition and delayed mortality, the overall efficacy of Fludora®Fusion WG‐SB was equal or better compared with other insecticides.ConclusionsFludora®Fusion showed overall equal or better efficacy than deltamethrin and bendiocarb alone against a pyrethroid‐resistant malaria vector population and can be considered as an alternative product for management of pyrethroid resistance in malaria vectors.
Genome‐wide occupancy of Arabidopsis SWI/SNF chromatin remodeler SPLAYED provides insights into its interplay with its close homolog BRAHMA and Polycomb proteins
Authors: Shu Jie , Chen Chen , Li Chenlong , Thapa Raj K. , Song Jingpu , Xie Xin , Nguyen Vi , Bian Shaomin , Liu Jun , Kohalmi Susanne E. , Cui Yuhai 
Published: January 2021

SUMMARYSPLAYED (SYD) is a SWItch/Sucrose Non‐Fermentable (SWI/SNF)‐type chromatin remodeler identified in Arabidopsis thaliana (Arabidopsis). It is believed to play both redundant and differential roles with its closest homolog BRAHMA (BRM) in diverse plant growth and development processes. To better understand how SYD functions, we profiled the genome‐wide occupancy of SYD and its impact on the global transcriptome and trimethylation of histone H3 on lysine 27 (H3K27me3). To map the global occupancy of SYD, we generated a GFP‐tagged transgenic line and used it for chromatin immunoprecipitation experiments followed by next‐generation sequencing, by which more than 6000 SYD target genes were identified. Through integrating SYD occupancy and transcriptome profiles, we found that SYD preferentially targets to nucleosome‐free regions of expressed genes. Further analysis revealed that SYD occupancy peaks exhibit five distinct patterns, which were also shared by BRM and BAF60, a conserved SWI/SNF complex component, indicating the common target sites of these SWI/SNF chromatin remodelers and the functional relevance of such distinct patterns. To investigate the interplay between SYD and Polycomb‐group (PcG) proteins, we performed a genome‐wide analysis of H3K27me3 in syd‐5. We observed both increases and decreases in H3K27me3 levels at a few hundred genes in syd‐5 compared to wild type. Our results imply that SYD can act antagonistically or synergistically with PcG at specific genes. Together, our SYD genome‐wide occupancy data and the transcriptome and H3K27me3 profiles provide a much‐needed resource for dissecting SYD’s crucial roles in the regulation of plant growth and development.
Financial development and natural resources: The dynamics of China’s outward FDI
Authors: Feng Ling , Ge Lulan , Li Zhiyuan , Lin Ching‐Yi 
Published: January 2021

AbstractThis paper studies the dynamics of China's outward FDI (OFDI) by examining the changing roles of host economy financial development and natural resources in the decision of OFDI destination choice. Using a country‐level panel data set of China's OFDI during 2003–2015, we find that Chinese multinationals show a strong and growing incentive of seeking natural resources of host economies, especially after the 2008 financial crisis, regardless of whether the host economy is a developed or developing economy. On the other hand, financial development of host economy is less relevant.
Specificity profile of αGal antibodies in αGalT KO mice as probed with comprehensive printed glycan array: Comparison with human anti‐Galili antibodies
Authors: Dobrochaeva Kira , Khasbiullina Nailya , Shilova Nadezhda , Knirel Yuriy , Obukhova Polina , Nokel Alexey , Kunetskiy Roman , Tsygankova Svetlana , Bello‐Gil Daniel , Costa Cristina , Mañez Rafael , Bovin Nicolai 
Published: January 2021

AbstractBackgroundThe α1,3‐galactosyltransferase gene‐knockout (GalT KO) mice are able to produce natural anti‐αGal antibodies apparently without any specific immunization. GalT KO mice are commonly used as a model immunological system for studying anti‐αGal responses to Gal‐positive xenografts in human. In this study, we compared the specificity of mouse and human αGal antibodies to realize the adequacy of the murine model.MethodsUsing hapten‐specific affinity chromatography antibodies against Galα1‐3Galβ1‐4GlcNAcβ epitope were isolated from both human and GalT KO mice blood sera. Specificity of isolated antibodies was determined using a printed glycan array (PGA) containing 400 mammalian glycans and 200 bacterial polysaccharides.ResultsThe quantity of isolated specific anti‐Galα antibodies corresponds to a content of <0.2% of total Ig, which is an order of magnitude lower than that generally assumed for both human and murine peripheral blood immunoglobulin, with a high predominance of IgM over IgG (95% vs 5%). Analysis using a printed glycan array has demonstrated that (a) antibodies from both species bind not only the Galα1‐3Galβ1‐4GlcNAcβ epitope, but also unrelated glycans; (b) particularly, for human (but not mouse) antibodies the best binders appear to be bacterial polysaccharides; (c) the profile of mouse antibodies is broader, it is noteworthy that they recognize a variety of human blood group B epitopes and even glycans without the α‐galactosyl residue.ConclusionsWe believe that the mouse model should be used cautiously in xenotransplantation experiments when the fine epitope specificity of antibodies is critical.
Heat Transfer Coefficient, Pressure Gradient, and Flow Patterns of R1234yf Evaporating in Microchannel Tube
Authors: Li Houpei , Hrnjak Pega 
Published: January 2021

Abstract
This paper presents the heat transfer coefficient, pressure gradient, and flow pattern of R1234yf in a microchannel tube. Both heat transfer coefficient and pressure gradient are presented against real saturation pressure, while flow pattern captures at the exit of data points are presented in the same plot. The experiment was conducted on a 24-port microchannel tube with an average hydraulic diameter of 0.643 mm. The experiment covers mass flux from 100 to 200 kg m−2s−1, heat flux from 0 to 6 kW m−2, vapor quality from 0 to 1, and inlet saturation temperature from 10 to 30 °C. Comparing the correlations to the HTC measurements at very low quality (about 0.1), Gorenflo, D., and Kenning, D. (2010, Pool Boiling, in: VDI Heat Atlas, 2nd ed, Springer, pp. 757–788) agree with the results. As vapor quality increases, pressure gradient increases. The adiabatic pressure gradient is a strong function of mass flux and saturation pressure (temperature). Flow patterns of R1234yf are also affected by mass flux and saturation pressure. The heat transfer coefficient is a strong function of mass flux and heat flux. The saturation temperature has a smaller effect on HTC in the condition range (10 – 30 °C). Under the test range, the accelerating pressure drop is insignificant compared to friction. Comparing to the results, Mishima, K., and Hibiki, T. (1996, “Some Characteristics of Air-Water Two-Phase Flow in Small Diameter Vertical Tubes,” Int. J. Multiph. Flow, 22(4), pp. 703–712) and Muller-Steinhagen, H., and Heck, K. (1986, “A Simple Friction Pressure Drop Correlation for Two-Phase Flow in Pipes,” Accessed March 1, 2018)., 20, pp. 297–308.) have small mean absolute error (MAE) to predict local pressure gradient. For the heat transfer coefficient, Sun, L., and Mishima, K. (2009, “An Evaluation of Prediction Methods for Saturated Flow Boiling Heat Transfer in Mini-Channels,” Int. J. Heat Mass Transf, 52(23–24), pp. 5323–5329) and Gungor, K. E., and Winterton, R. H. S. (1986, “A General Correlation for Flow Boiling in Tubes and Annuli,” Int. J. Heat Mass Transf, 29(3), pp. 351–358) have an MAE less than 30%.
Parametric Analysis of Microfluidic Cooling Systems for Three-Dimensional-Stacked Silicon Microelectronics by Inferential Statistic Approaches
Authors: Moreno-Torres Tomas , Lorenzini Daniel , Joshi Yogendra , Hernandez-Guerrero Abel , Luviano-Ortiz J. Luis 
Published: January 2021

Abstract
This work is a numerical study of microfluidic cooling of integrated circuits (ICs), using embedded micropin-fins on a silicon chip. The study considers non-uniform chip heat fluxes (250–500 W/cm2) and variable pin fin density using DI water as coolant. A parametric analysis was performed, using the theory of design of experiments (DoE) in order to find the best performing configurations. The proposed factorial design considers six geometrical parameters resulting in 64 microfluidic cooling configurations. The pressure drop and average chip temperatures were obtained for each model to determine the importance of input parameters utilizing a statistical approach. Results from this optimization point to different suitable configurations in which the maximum device temperature is below 60 °C, under moderate pressure drops below 80 kPa. This work takes advantage of numerical models and statistical approaches to seek optimal designs of microfluidic cooling systems and to identify key parameters that have influence on their global performance. In addition, alternative configurations are also assessed for cases in which thermal or hydraulic parameters could be traded-off depending on the application. The results from this study are helpful for the design of chip thermal management with nonuniform power distribution.
Plastic Limit Analysis Using the Simplified Theory of Plastic Zones
Authors: Hübel Hartwig 
Published: January 2021

Abstract
The simplified theory of plastic zones (STPZ) was mainly developed to determine strain ranges and accumulated strains in the state of shakedown at cyclic loading between prescribed levels of loading. Kinematic hardening is an indispensable feature of the STPZ. The plastic limit load, however, is defined for monotonic loading and elastic–plastic material behavior without hardening. Simply assigning a zero value or a numerically very low value of the tangent modulus when applying the STPZ is generally not possible due to arising numerical instabilities. It is, therefore, not immediately obvious how the STPZ can be used to determine the maximum load level that can be applied to a structure without developing a kinematic mechanism. This paper describes the theory and the analysis steps required and provides some illustrative examples. Typically, between one and three linear elastic analyses and some local calculations are required to provide either the exact value or at least a reasonable estimate of a range of the plastic limit load, as well as of the associated stress and strain fields and displacements that are not provided by classical limit analysis.