bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Relaxation Time in Piezoelectric Hollow Cylinder by Finite Element Technique
Authors: Alqahtani Zuhur , Abbas Ibrahim , El‐Bary Alaa A. , Almuneef Areej 
Published: February 2025

ABSTRACTThis study examines the thermo‐electro‐elastic responses of a long hollow cylindrical piezoelectric material due to a pulse heating flux on its surface. Formulations suggested by Lord and Shulman for generalized piezothermoelastic systems are used. The response of the vessel is modeled under axisymmetric conditions, leading to the formulation of three coupled governing equations: the motion, Maxwell and the energy formulations. The finite element approach is used to solve these equations numerically. The Newmark time‐marching methodology is used to derive the temporal evolution. The presentation of novel numerical results provides insights into the dynamic behaviors of the piezoelectric cylinder under transient heat settings. The responses of pulse heating flux and relaxation time on the coupling between mechanical, thermal and electrical fields are highlighted in this work, providing useful.
High prevalence of small intestinal bacterial overgrowth and intestinal methanogen overgrowth in endometriosis patients: A case–control study
Authors: Halfon Philippe , Estrade Jean‐Philippe , Penaranda Guillaume , Choucroun Nathalie , Bouaziz Jérôme , Nicolas‐Boluda Alba , Retornaz Frédérique , Gurriet Brice , Plauzolles Anne 
Published: February 2025

AbstractObjectiveThe purpose of this study is to raise awareness of small intestinal bacterial overgrowth (SIBO) and intestinal methanogen overgrowth (IMO) prevalence among patients with endometriosis to improve global recommendations in the standard of care for endometriosis.MethodsThis case–control study included a cohort of 1027 women who underwent the lactulose breath test (LBT) during their healthcare check‐up to diagnose SIBO and/or IMO from November 2021 to June 2023. One hundred and forty‐eight endometriosis patients were selected based on magnetic resonance imaging or a histological assessment. Each were matched with an equal number of women without endometriosis based on the exact age.ResultsSIBO/IMO prevalence was significantly higher among women with endometriosis, with up to 136 out of 148 who tested positive, 91.9% (95% confidence interval [CI] 86.3–95.7%) against 123 in the control group, 83.1% [76.1–88.8%], P = 0.0223. Women with endometriosis showed a significantly higher incidence of altered transit than those without (85.8 vs. 71%, P = 0.0019) and an increased prevalence of constipation (67.8 vs. 44.7%, P = 0.0017) and dizziness (44.8 vs. 28.7%, P = 0.0245). Overall, methane overgrowth accounted for up to 63.2% in women with endometriosis who tested positive for methane overgrowth. SIBO H2 was associated with a higher risk of developing diarrhea (P = 0.0027), whereas those positive for IMO were at a higher risk of developing acid reflux (P = 0.0132).ConclusionAbnormal digestive overgrowth should be assessed in all endometriosis cases, as this approach could offer a new therapeutic strategy.
Unravelling the Nuances of Data With Quantile Regression: A Comprehensive Tutorial
Authors: Mabire‐Yon Renaud 
Published: February 2025

ABSTRACTIn applied psychology, traditional statistical methods often provide only a broad overview, potentially overlooking nuanced variable relationships. This article presents a comprehensive tutorial on quantile regression (QR), a statistical modelling technique ideally suited for psychological data analysis. Unlike conventional regression, QR examines relationships across different quantiles of the data distribution, revealing complex dynamics and offering robustness to non‐normality and heteroscedasticity. We demonstrate its utility through a practical example, analysing the relationship between age and life satisfaction, supported by annotated R code. The tutorial emphasises grounding QR in a sound theoretical framework and introduces the quantile loss approach as an alternative to p value interpretation. By providing both theoretical understanding and practical tools, this tutorial aims to empower researchers to improve the depth and reproducibility of their findings in psychological research.
Microplastics Exposure Causes the Growth Hormone Resistance on the Stem Cell
Authors: Zhang Meng , Zhang Ruoting , Kong Yuebing , Li Jiawen , Wang Guoxia , Wu Deyi , Lan Hainan , Wu Min 
Published: February 2025

ABSTRACTWith the large range of applications for plastic products, the potential hazards of polystyrene microplastics (PS‐MPs) as a hazardous substance have been widely concerned. Mesenchymal stem cells (MSCs) are important cells in the body with high self‐renewal ability, multidirectional differentiation potential and low immunogenicity. Growth hormone (GH) has important biological regulatory effects on MSCs. However, the toxicological effects of PS‐MPs on the role of GH in hMSCs are unclear yet. In this work, we explored the effects of PS‐MPs on the biological activity of GH in hMSCs. Initially, we conducted experiments to investigate the cellular behavior of GH in hMSCs. It is noteworthy that poststimulation with PS‐MPs, there was a significant reduction in the quantity of GH entering the cytoplasm, with almost negligible distribution observed in the cell nucleus. Consequently, we proceeded to examine the GH/GHR‐mediated signaling pathways. The data revealed that poststimulation with PS‐MPs, the downstream signaling pathways, including JAK2‐STATs1/3/5, were significantly downregulated. To elucidate this intriguing finding, we delved further into the molecular mechanisms underlying the desensitization of GH/GHR signaling induced by PS‐MPs. Experimental data demonstrated that the entry of PS‐MPs into the cells resulted in a significant increase in intracellular reactive oxygen species (ROS), leading to cellular senescence. In summary, PS‐MPs may induce desensitization of GH signaling in hMSCs through the ROS‐induced cellular senescence. This study provides crucial insights into the biological effects of PS‐MPs on the GH bioactivity in hMSCs.
Effect of Nano Selenium on Cadmium Chloride‐Induced Infertility in Male Wistar Rats
Authors: Taromsari Shahrbano , Eidi Akram , Mortazavi Pejman , Modaresi Mehrdad 
Published: February 2025

ABSTRACTSelenium (Se) is an essential trace element with well‐documented health benefits, including antioxidative, anti‐inflammatory, antiapoptotic, and anticarcinogenic properties. Selenium nanoparticles (nano‐Se) represent an advanced Se delivery system characterized by superior bioavailability and a reduced risk of Se‐related toxicity. This study investigates the protective efficacy of nano‐Se against cadmium chloride (CdCl2)‐induced infertility in adult male Wistar rats. The experimental design involved random allocation of the rats into nine groups: a healthy control group, a vehicle control group, three groups receiving nano‐Se alone at 0.05, 0.1, and 0.2 mg/kg b.w./day, a group exposed to CdCl2 to induce infertility, and three CdCl2‐exposed groups treated with nano‐Se. After 30 days of treatment, the animals were euthanized for biochemical and histopathological assessments. The findings revealed that nano‐Se administration ameliorated the detrimental effects of treatment CdCl2 on serum testosterone levels. Additionally, nano‐Se significantly reduced malondialdehyde levels and enhanced the activity of antioxidant enzymes in testicular homogenates. Histological analyses further demonstrated that nano‐Se preserved the structural integrity of testicular tissue in the CdCl2‐induced fertility model. Nano‐Se modulated apoptotic pathways, as evidenced by the suppression of Bax expression and upregulation of Bcl2 expression in testicular tissue. Furthermore, nano‐Se mitigated the overexpression of aquaporin‐9 in CdCl2‐exposed rats. Collectively, these results provide robust biochemical, histological, and biochemical evidence supporting the potential therapeutic utility of nano‐Se in mitigating testicular dysfunction.
To Fill a Hollow Core: Roles of Firm Knowledge When Outsourcing Core Component During Technological Change
Authors: Park Woo‐Yong , Khurshid Faisal , Tangpong Chanchai 
Published: February 2025

ABSTRACTThe innovation literature has been marked by contrarian views regarding the roles of firms' knowledge accumulation with regards to outsourced core components. To reconcile these views, we draw on the behavioral theory of the firm and the technological evolution literature in hypothesizing firms' local search as a mechanism by which firms' accumulated knowledge affects their product performance. Firms' in‐house knowledge can expose them to an accumulated knowledge trap, as firms' accumulated knowledge tends to escalate their local search for a solution to a new technological challenge, but the impact of the local search on performance is unlikely to be materialized. We maintain that firms' accumulated knowledge can make them more prone to the accumulated knowledge trap before rather than after the dominant technology has emerged. We further hypothesize that prior exploratory experiences and suppliers' outsourced component knowledge can reduce firms' susceptibility to such a knowledge trap before the dominant technology emergence, but their moderating roles fade away after the dominant technology emergence. Data from the U.S. Hybrid Electric Vehicle drivetrain market support our hypotheses. Our findings enrich the current literatures on the behavioral theory of the firm and technological evolution while reconciling the contrarian views in the innovation literature.
Evaluation of ecotoxicological effects of sophorolipids on duckweed, Spirodela polyrrhiza
Authors: Shao Junqian , Li Guangshun , Jiang Rongyue , Jin Zhigang , Han Huipei , Huo Yanfeng , Xun Shangpei , Ma Xiaojing 
Published: February 2025

AbstractThis study evaluated the ecotoxicological effects of sophorolipids (SLs), biosurfactants with potential environmental applications, on the aquatic plant Spirodela polyrhiza (duckweed). Key growth indicators, including biomass, foliose thalli, and leaf area, were examined under varying SL concentrations. Results indicated that low to moderate SL concentrations (below 100 mg/L) had minimal adverse effects on duckweed growth, whereas higher concentrations (200–300 mg/L) significantly inhibited growth and triggered stress responses. Morphological and physiological assessments revealed that elevated SL concentrations caused substantial frond wilting, root hair damage, and reductions in photosynthetic pigments. Antioxidant responses, such as glutathione (GSH), malondialdehyde (MDA), and catalase (CAT) enzyme activities, increased adaptively at low to moderate SL concentrations but declined at higher levels, indicating severe oxidative stress. Despite these adverse effects, S. polyrhiza exhibited a remarkable ability to degrade SLs even at high concentrations, demonstrating the exceptional biodegradability of SLs. Overall, the findings emphasize the relative safety of SLs at low to moderate concentrations in aquatic environments, underscoring their potential as environmentally friendly surfactants when used responsibly.
Biochemical and Molecular Characterization of Soil‐Isolated Exoelectrogens and Evaluation of Their Electrochemical Properties via Single‐Chambered Mediator‐Free Microbial Fuel Cell
Authors: Dar Parvaiz Ahmad , Yahya Wan Zaireen Nisa , Khan Azmat Ali , Kumar Amit , Agrawal Sharad 
Published: February 2025

AbstractMicrobial fuel cells are utilized in electromicrobiology for the purpose of cleaning wastewater and producing electricity. Anaerobically, MFCs use microbial catalysis in the anodic compartment to transform the chemical energy stored in organic and inorganic molecular bonds. Using the soil sample, four exoelectrogens are isolated. Each of the four single‐chambered mediator‐less microbial fuel cell design are used to inject the extracted soil exoelectrogens. A nutritional medium is used to operate the reactors in batches of 15 days. The exoelectrogen ISO4 (Bacillus amyloliquefaciens strain NSB4), followed by ISO3 (cereus strain BXC6), ISO2 (Bacillus sp. (in: Bacteria) strain 4N), and ISO1 (Staphylococcus argenteus strain D7) achieve the best growth rates. On average, data on energy generation shows that MFCs with ISO4 have the maximum voltage and power density at 1024 mV external resistance (1 kΩ), followed by ISO3 at 609 mV, ISO2 at 560 mV, and ISO1 at 487 mV. Power densities of isolates are recorded as: 41.281 mW/m2, 29.241, 12.723, and 3.552 mW/m2 for ISO4, ISO3, ISO2, and ISO1, respectively. The research finds that the energy output of MFC reactors is affected by the exoelectrogen substrates. Cyclic voltammetry (CV) experiment demonstrates that exoelectrogens directly transport electrons to the anode surface via cytochromes and other substances associated with the cell membrane. It has been previously difficult to produce power from pure isolates, but new research reveals that this is no longer an issue. Pure cultures of exolectrogens use to generate current also show a broad substrate utilization spectrum, in line with previous studies.
Synthesis and Characterization of Novel Selenium Bearing 24‐ and 28‐Membered Macrocyclic Schiff Bases and Their Reactivity with Hg (II) Ion
Authors: Banerjee Bhaskar , Verma Rajaneesh Kumar , Jain Nidhi , Yadav Tarun , Alheetyc Mustafa A. , Yahya M. Z. A. , Singh Munendra , Verma Vinay Kumar , Singh Ram Chandra 
Published: February 2025

AbstractThe present study reports the synthesis of novel selenium containing 24 (1)‐ and 28 (2)‐membered macrocyclic Schiff base ligands and their reactivity with Hg(II) metal ion to form complex 3 and 4, respectively. The synthesis of the ligands are carried out by a simple condensation of 2,6‐dibenzoyl‐4‐methylphenol and bis(aminoethyl/propyl)selenides in [2+2] dipodal manner in dry acetonitrile solvent under inert atmosphere. Furthermore, the reaction between the 24‐ and 28‐membered selenium containing ligands and Hg(II) metal ion are carried out in dry methanol in argon atmosphere. Following the complexation of both the ligands, 1 (C50H48O2N4Se2) and 2 (C54H56O2N4Se2) when reacted with HgBr2 yields monometallic complexes 3 and 4 with molecular composition of C50H50O3N4Se2HgBr2 and C54H58O3N4Se2HgBr2, respectively, as calculated via elemental analysis and mass spectrometry. Moreover, the synthesized compounds are also characterized by various physicochemical techniques to determine the structure and reactivity, which includes UV–vis, FT‐IR, multinuclear (1H and 77Se) NMR, and cyclic voltammetry.
Epoxy and Fused Silica Composite for Radio Frequency and Microwave Applications
Authors: Kumar Surendra , Gupta Pallavi , Rajauriya Manisha 
Published: February 2025

AbstractFused silica and epoxy composite are prepared and presented in this paper for the microwave applications. The mixing of the fused silica and epoxy is done using powder processing techniques. Fused silica particles are working as a filler material in the epoxy matrix. The dielectric loss of the fabricated fused silica and epoxy composite is found to be 0.002 at 9.5 GHz, which is lower than the dielectric loss (0.012) of the unfilled epoxy. The dielectric constant of the fabricated fused silica and epoxy composite (εr 2.5) approximately remains same as the unfilled epoxy. Thus, a new polymer–composite is formed for the low‐loss microwave propagation with improved mechanical and thermal properties because of the presence of the ceramic filler in epoxy matrix. The practical value holds good in agreement with the theoretical approaches.
Synthesis, Characterization, and Brine Shrimp (Artemia salina) Toxicity Evaluation of Nanocomposites Carrier Phytic Acid/Chitosan/Magnetic Iron Oxide Nanoparticles
Authors: Asey Monica Namizie , Abdullah Che Azurahanim Che , Abdelmonem Mohamed , Esa Norhaizan Mohd , Rahman Mohd Basyaruddin Abdul 
Published: February 2025

AbstractThe use of polymer‐coated magnetic iron oxide nanoparticles (MIONs) to deliver drugs to a specific target site is among the most efficient strategies. We have developed MIONs coated with chitosan (CS) polymer, preloaded with the phytodrug phytic acid (PTA), for drug delivery applications. To fully understand the crystalline structure and surface morphology of the prepared composite nanocarrier, it is thoroughly characterised by powder X‐Ray Diffraction, Fourier transform infrared spectroscopy, thermogravimetric analyses, vibrational sample magnetometer, and transmission electron microscopy. Additionally, brine shrimp (Artemia salina) are used to assess the in vitro toxicity of phytodrug‐loaded MIONs‐CS nanostructures. Our studies on brine shrimp have demonstrated that both the phytodrug and nanocomposite have excellent activity. As a result, our PTA‐loaded MIONs/CS nanocomposite can be recommended for real‐time diagnostic CS.
Measuring temperature in polyvinylpyrrolidone (PVP) solutions using MR spectroscopy
Authors: Gai Neville D. , Dong Ruifeng , van der Veen Jan Willem , Ouwerkerk Ronald , Pierpaoli Carlo 
Published: February 2025

AbstractBackgroundPolyvinylpyrrolidone (PVP) water solutions could be used for cross‐site and cross‐vendor validation of diffusion‐related measurements. However, since water diffusivity varies as a function of temperature, knowing the temperature of the PVP solution at the time of the measurement is fundamental in accomplishing this task.PurposeMR spectroscopy (MRS) could provide absolute temperature measurements since the water peak moves relative to any stable peak as temperature changes. In this work, the PVP proton spectrum was investigated to see if any stable peaks would allow for temperature determination. Reproducibility and repeatability for three scanners from three vendors were also assessed.MethodsA spherical 17 cm container filled with 40% PVP w/w in distilled water was used for the experiments. A Point REsolved Spectroscopy Sequence (PRESS) with water suppression was employed on three 3T scanners from different vendors—GE, Siemens, and Philips. Frequency separation (in ppm) between peaks was measured in a voxel at the location of a fiber optic temperature probe and mapped to probe measured temperature. The center peak of the first methylene proton triplet closest to water peak was selected for analysis in jMRUI due to its ease of identification and echo time shift invariance. Shift in ppm of the central methylene peak proton was mapped against measured temperatures.Repeatability and reproducibility across the three scanners were determined at room temperature using 10 repeated PRESS scans. MRS established ppm shift versus temperature relationship was used to predict temperature in different PVP phantoms which were then compared against fiber optic probe measured temperature values.ResultsSeveral 1H peaks were identified on all scans of the PVP phantom. The water peak moved by ∼−0.01 ppm/°C on the three scanners relative to a central methylene peak. The maximum mean absolute temperature difference over a temperature range of 18–35°C between the three scanners was 0.16°C while the minimum was 0.057°C. Repeatability on each scanner was excellent (std range: 0.00–0.14°C) over 10 repeated PRESS scans. Reproducibility across the three scanners was also excellent with mean temperature difference between scanners ranging between 0.1 and 0.4°C. Temperature values from MRS were within prediction bounds on the three scanners for another in‐house prepared 40% PVP phantom (maximum difference<0.3°C), while they were consistently overestimated for another 30% PVP phantom (<1°C) and underestimated for a CaliberMRI 40% PVP phantom (<2.8°C).ConclusionsPVP solutions exhibit stable proton peaks, one of which was used for assessing the temperature of the solution using MR proton spectroscopy. These measurements are fast and feasible with standard sequences and postprocessing MRS software and provide fundamental information for calibration of diffusion MRI using PVP solutions.
Urinary Diversion as Last Option After Failed Artificial Urinary Sphincter and Iatrogenic Devastated Bladder Outlet
Authors: Holm Henriette Veiby , Lumen Nicolaas , Ludwig Tim Alexander , Fisch Margit , Hofer Matthias , Brandes Steven , Kurtzman Jane , Simhan Jay , Venkatesan Krishnan , Gómez Reynaldo Guillermo , Nikolavsky Dmitriy , Tryfonyuk Liliya , Martins Francisco Estrócio 
Published: February 2025

ABSTRACTObjectivesTo describe functional outcomes and identify risk factors for artificial urinary sphincter (AUS) failure and need for urinary diversion (UD) in patients with iatrogenic devastated bladder outlet (DBO). Our hypothesis was that pelvic radiation or ablative therapy (RT/AT) increases the risk of complications compared to surgery alone.MethodsMulticenter, retrospective study of patients with complications from previous treatments, subsequent AUS failure and unsalvageable DBO, ultimately requiring UD between 2008 and 2020. Demographics, comorbidities, prior treatments, reconstructive attempts, and type of UD ± extirpative procedures were reviewed. The patients were divided into two groups according to their primary treatment: G1 (RT/AT±surgery) and G2 (surgery alone).ResultsWe identified 34 patients with DBO requiring UD after AUS failure. Primary diagnoses were prostate cancer (88.2%), anal cancer (2.9%), and benign prostatic obstruction (8.8%). Primary treatments were RT/AT±surgery in 27 (G1) and surgery alone in seven (G2). Complications included bladder outlet obstruction, fistulae, and urinary incontinence. Number of AUS implantations (range 1–4) and failed reconstructive attempts before UD (range 1–12) were more prevalent in G2. Time from completion of primary treatment to first complication was longer in G1, while from first complication to UD shorter in G1. Details regarding UD, extirpative procedures, and further complications are described.ConclusionsExposure to pelvic RT/AT and complexity of primary surgical treatments combined with AUS complications and repeated failed attempts at surgical reconstruction can generate a high‐risk patient profile associated with an unsalvageable DBO leading patients to ultimately opt for UD as a trade‐off for QoL.
Variation in the Definitions of Urinary Retention in Studies of Intravesical Botulinum Toxin for Idiopathic Overactive Bladder: A Narrative Systematic Review
Authors: Stavrou Stephanie , Paynter Jessica A. , Carins Thomas , Qin Kirby R. , Brennan Janelle 
Published: February 2025

ABSTRACTPurposeTo categorise and quantify definitions of urinary retention reported in studies assessing botulinum toxin (BoNT) injections for idiopathic overactive bladder (iOAB) syndrome.Materials And MethodsA narrative systematic review was conducted using three databases: EMBASE (via Ovid), PubMed, and SCOPUS. Inclusion criteria comprised studies published as full‐text articles in English involving adults receiving BoNT injections (any formulation) for iOAB syndrome, where urinary retention was reported as an outcome.ResultsFrom 1986 screened studies, 135 were assessed, and 57 met the eligibility criteria for the narrative systematic review. Reported rates of urinary retention varied widely, ranging from 0% to 42.6%. A definition of urinary retention was provided in 33 studies (57.9%), which were broadly categorised as follows.

Post‐void residual (PVR) volume threshold: 14 studies (21.5%).
Inability to void: 6 studies (9.2%).
Initiation of clean intermittent catheterisation (CIC): 6 studies (9.2%).
PVR volume threshold and initiation of CIC/indwelling catheterisation (IDC): 6 studies (9.2%).
Bladder symptoms and PVR volume threshold and initiation of CIC/IDC: 6 studies (9.2%).
Bladder symptoms and PVR volume threshold: 3 studies (4.6%).Notably, 24 studies (42.1%) omitted a definition altogether.ConclusionsUrinary retention rates varied significantly between studies, likely due to the heterogeneous definitions used. The omission of definitions in nearly half of studies further complicates efforts to accurately inform and consent patients regarding the risk of urinary retention and the need for CIC/IDC after intravesical BoNT injection. Standardised definitions are urgently needed to enhance research, improve clinical practice, and support informed patient counselling.