bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of climate change on livestock productivity: A review
Authors: Madziga I. I. 
Published: March 2021

Climate change is a long-term shift in the statistics of the weather such as temperature, radiation, and wind and rainfall characteristics of a particular region. Sustainability in livestock production system is largely affected by climate change. A disproportion between metabolic high temperature production inside the animal body and its dissipation to the surroundings results to heat stress under high air temperature and humid climates. The foremost reaction of animals under thermal weather is an increase in respiration rate, rectal temperature and heart rate. The anticipated rise in temperature due to climate change is likely to aggravate the heat stress in livestock, adversely affecting their productive and reproductive performance and even death in extreme cases. The predicted negative impact of climate change on agriculture would also adversely affect livestock production by aggravating the feed and fodder shortages. The paper mainly reviews the impacts of climate change on livestock productive performance.
Le changement climatique est un changement à long terme dans les statistiques météorologiques telles que la température, le rayonnement et les caractéristiques du vent et des précipitations d'une région particulière. La durabilité du système de production de bétail est largement affectée par le changement climatique. Une disproportion entre la production métabolique à haute température à l'intérieur du corps de l'animal et sa dissipation dans l'environnement entraîne un stress thermique sous des températures élevées de l'air et des climats humides. La réaction la plus importante des animaux sous temps thermique est une augmentation de la fréquence respiratoire, de la température rectale et de la fréquence cardiaque. L'augmentation prévue de la température due au changement climatique est susceptible d'aggraver le stress thermique du bétail, affectant négativement ses performances productives et reproductives et même la mort dans les cas extrêmes. L'impact négatif prévu du changement climatique sur l'agriculture aurait également un effet négatif sur la production animale en aggravant les pénuries d'aliments et de fourrage. Le document passe principalement en revue les impacts du changement climatique sur les performances de production de bétail.
A review of strategies aimed at adapting livestock to volatile climatic conditions in Nigeria
Authors: Oyeniyi F. G. , Ewuola E. O. 
Published: March 2021

Despite their crucial importance, limited information exists about how livestock are affected by climate change in Nigeria. Changing climatic patterns are manifested through occurrences like abrupt temperature increase, dwindling rainfall pattern, rise in spells of drought and flood. These conditions exert different effects across the geographical landscape of the country, which can broadly be classed as Semiarid, Sahel and Derived Savannah, respectively as well as Forest and Montane. Livestock provide humans with the full complement of amino acids, which are the only known natural suppliers of Vitamin B12 and equally supply iron, calcium, iodine and zinc. In addition, livestock accounts for 40% of Agricultural Gross Domestic Product and significantly contributes to enhancing rural livelihood. Stress conditions are induced in livestock by harsh weather conditions that reduce the feed available to them as well as impede growth rate and reproduction efficiency and disease incidence which may eventually result in death. In the light of the livestock benefits to humanity, it is necessary to devise means of making their climate resilient. Some of the proven strategies include animal genetic improvement for stress tolerance, growing disease resistant, early maturing and drought tolerant crops, selecting for and rearing climate tolerant animal species and breeds.

Malgré leur importance cruciale, il existe peu d'informations sur la manière dont le bétail est affecté par le changement climatique au Nigéria. Le changement des modèles climatiques se manifeste par des événements tels que l'augmentation brutale de la température, la diminution des précipitations, l'augmentation des périodes de sécheresse et d'inondation. Ces conditions exercent des effets différents sur le paysage géographique du pays, qui peuvent être globalement classés comme semi-aride, sahélien et savane dérivée, respectivement, ainsi que forêt et montagne. Le bétail fournit aux humains le complément complet d'acides aminés, qui sont les seuls fournisseurs naturels connus de vitamine B12 et fournissent également du fer, du calcium, de l'iode et du zinc. En outre, l'élevage représente 40% du produit intérieur brut agricole et contribue de manière significative à l'amélioration des moyens d'existence ruraux. Les conditions de stress sont induites chez le bétail par des conditions météorologiques difficiles qui réduisent les aliments disponibles pour eux et entravent le taux de croissance, l'efficacité de la reproduction et l'incidence des maladies qui peuvent éventuellement entraîner la mort. À la lumière des avantages de l'élevage pour l'humanité, il est nécessaire de concevoir des moyens de rendre leur résilient climatique. Certaines des stratégies éprouvées comprennent l'amélioration génétique animale pour la tolérance au stress, la culture de cultures résistantes aux maladies, à maturation précoce et à la sécheresse, la sélection et l'élevage d'espèces et de races animales tolérantes au climat.
Exploring National Culture Impact on Logistics Performance
Authors: Kesavan Deepak P. , Deif Ahmed M. 
Published: March 2021

Abstract
The increased logistics complexity due to supply chain globalization requires deeper understanding of a country's logistics performance. This performance is usually captured through infrastructure, services, and procedure elements and is understood in operational and economical terms. This exploratory research adds a social view to understand logistics performance variation across countries through focusing on their national culture dimensions. Using secondary data from the international Logistics Performance Index (LPI) report as well as the scores from Hofstede national culture dimension surveys, the impact of national culture on logistics performance was explored. Statistical results showed Power Distance and Uncertainty Avoidance dimensions were found to have a negative correlation with LPI while Individualism as well as Long-Term Orientation were both positively correlated to LPI. This cultural understanding adds to the growing social literature research on logistics performance and can guide logistics managers in their decisions regarding where and when to locate their resources.
Samenhang in beleid op het terrein van veiligheid en justitie
Authors: Blank Jos , van Heezik Alex 
Published: March 2021

Policy coherence in the area of safety and justice – A longitudinal analysis of service delivery per euro spent in the S&J sector during the period 1980-2016
In the safety and justice policy area, there is a strong intertwining between performances of the various sectors, such as police, judiciary and prison system. The question is whether policy takes these interdependencies into account sufficiently. Are the resources used – from a broader wealth perspective – optimally allocated amongst the various safety and justice provisions? The authors answer this question on the basis of an integrated time series analysis of the productivity development of the Dutch safety and justice system in the period 1980-2016. The analysis shows that productivity of safety and justice services has hardly changed since 1980. At best, in 2016, citizens will receive as much value per euro of taxpayers’ money as in 1980, but probably slightly less. It is striking, however, that the S&J system as a whole operates more efficient than the sum of its parts (the individual sectors). There have been substantial changes in the allocation of resources over time. Obviously money from the police was transferred to the judiciary and municipalities.
Todos os caminhos levam a Cedamusa: o antimodernismo pós-moderno de Padre∕Dom Rifan na constituição do neotradicionalismo da Administração Apostólica Pessoal São João Maria Vianney
Authors: Zaquieu-Higino Paulo Victor 
Published: March 2021

Atualmente, observa-se o crescimento do número de adeptos às vertentes conservadoras de movimentos políticos e religiosos no cenário brasileiro e mundial. No catolicismo, destacam-se os chamados tradicionalistas, representantes da ala ultraconservadora da Igreja. Os “tradicionalistas de Campos”, em específico, encontram-se divididos entre as ideias apologéticas do Concílio de Trento, as exigências da sociedade (pós)moderna e a reforma proposta pelo Vaticano II, necessitando desenvolver adaptação do seu modo de comunicar seu ideal antimodernista, sem romper sua identidade idealizada. Nesse contexto, é produzida nova identidade (a Administração Apostólica Pessoal São João Maria Vianey) dentro de uma pluralidade de identidades, comunicando-se com estas, ainda que para negá-las – a Igreja Pós Conciliar e a sociedade onde está inserida. Portanto, nesta pesquisa, pretende-se analisar o ethos discursivo de Padre/Dom Rifan, nos seus livros Quer agrade, quer desagrade, escrito quando era porta voz da cismática União sacerdotal São João Maria Vianney, e o livro Sementes, escrito como bispo e administrador apostólico da referida Administração Apostólica. A partir da metodologia e referencial teórico da Análise do Discurso de filiação francesa, busca-se uma compreensão das bricolagens feitas pelo atual bispo administrador, que constituem o neotradicionalismo da Administração Apostólica, a qual, inspirada por seu líder, desenvolve um antimodernismo pós-moderno.

Palavras-chave: Catolicismo. Antimodernismo. Tradicionalismo. Ethos Discursivo.
Experiencias de victimización en mujeres sin hogar del sur de España
Authors: Alonso Pardo Alicia , Palacios Ramírez José , Iniesta Martínez Almudena 
Published: March 2021

La feminización de la pobreza ha dado lugar a un aumento del número de mujeres sin hogar. El objetivo de este trabajo, basado en una investigación cualitativa, es conocer la presencia de experiencias de victimización en población sin hogar femenino tanto de manera previa a la situación de calle como durante la misma. Los resultados han puesto de manifiesto el impacto que tiene la vulnerabilidad y violencia de género en sus trayectorias biográficas. Asimismo, muestran cómo la vulnerabilidad sexual está muy presente en la experiencia de sinhogarismo femenino entendida como una particularidad de género de esta población.
The feminisation of poverty has give rise to the number of homeless women. The aim of this work, based on a qualitative research methodology, is to know about the existence of victimisation experiences among the women homeless population both before and during the homeless situation. The results have shown vulnerability and gender´s violence impact on biographical trajectories of the interviewed women. As well, it showed how the sexual vulnerability has a significant presence in the women homelessness experience, being possible understanding that as a real gender particularity.
Therapeutic targeting with DABIL‐4 depletes myeloid suppressor cells in 4T1 triple‐negative breast cancer model
Authors: Parveen Sadiya , Siddharth Sumit , Cheung Laurene S. , Kumar Alok , Shen Jessica , Murphy John R. , Sharma Dipali , Bishai William R. 
Published: March 2021

In many solid tumors including triple‐negative breast cancer (TNBC), upregulation of the interleukin‐4 receptor (IL‐4R) has been shown to promote cancer cell proliferation, apoptotic resistance, metastatic potential, and a Th2 response in the tumor microenvironment (TME). Since immunosuppressive cells in the TME and spleen including myeloid‐derived suppressor cells (MDSCs) and tumor‐associated macrophages (TAMs) also express the IL‐4R, we hypothesized that selective depletion of IL‐4R‐bearing cells in TNBC would result in the direct killing of tumor cells and the depletion of immunosuppressive cells and lead to an enhanced antitumor response. To selectively target IL‐4R+ cells, we employed DABIL‐4, a fusion protein toxin consisting of the catalytic and translocation domains of diphtheria toxin fused to murine IL‐4. As anticipated, DABIL‐4 has potent cytotoxic activity against TNBC cells both in vitro and in vivo. We demonstrate in the murine 4T1 TNBC model that DABIL‐4 significantly reduces tumor growth, splenomegaly, and lung metastases. Importantly, we also show that the administration of DABIL‐4 results in the selective depletion of MDSCs, TAMs, and regulatory T cells in treated mice, with a concomitant increase in IFN‐γ+ CD8 effector T cells in the TME. Since the 4T1 antitumor activity of DABIL‐4 was largely diminished in IL‐4R knockout mice, we postulate that DABIL‐4 functions primarily as an immunotherapeutic by the depletion of MDSCs, TAMs, and regulatory T cells. NanoString analysis of control and treated tumors confirmed and extended these observations by showing a marked decline of mRNA transcripts that are associated with tumorigenesis and metastasis. In conclusion, we demonstrate that DABIL‐4 targeting of both tumor and immunosuppressive host cells likely represents a novel and effective treatment strategy for 4T1 TNBC and warrants further study.
Therapeutic RNA Delivery for COVID and Other Diseases
Authors: Dobrowolski Curtis , Paunovska Kalina , Hatit Marine Z. C. , Lokugamage Melissa P. , Dahlman James E. 
Published: March 2021

AbstractRNA can alter the expression of endogenous genes and can be used to express therapeutic proteins. As a result, RNA‐based therapies have recently mitigated disease in patients. Yet most potential RNA therapies cannot currently be developed, in large part because delivering therapeutic quantities of RNA drugs to diseased cells remains difficult. Here, recent studies focused on the biological hurdles that make in vivo drug delivery challenging are described. Then RNA drugs that have overcome these challenges in humans, focusing on siRNA to treat liver disease and mRNA to vaccinate against COVID, are discussed. Finally, research centered on improving drug delivery to new tissues is highlighted, including the development of high‐throughput in vivo nanoparticle DNA barcoding assays capable of testing over 100 distinct nanoparticles in a single animal.
3D Stacked Near‐Field Electrospun Nanoporous PVDF‐TrFE Nanofibers as Self‐Powered Smart Sensing in Gait Big Data Analytics
Authors: Lo Wei Cheng , Chen Chih Chia , Fuh Yiin Kuen 
Published: March 2021

AbstractThis study describes a new stacked structure with porous nanofiber‐based piezoelectric nanogenerator by near‐field electrospinning. The 3D‐stacked porous nanofibers structure enhances the stress concentration effect such that the PVDF‐TrFE nanofibers can promote higher performance in electrical output. By mimicking the additive manufacturing in near‐field electrospinning (NFES) setup, structurally simple and piezoelectrically effective fabrication is capable of converting stacked porous PVDF‐TrFE nanofiber into a high‐performance sensor. The electrical voltage output performance is enhanced more than 2.7 times compared with primitive PVDF‐TrFE nanofiber. Furthermore, a self‐powered foot pressure recognition statistical system and an individual gait biometrics system are developed to provide gait recognition and a new biometrics technology. A personal sequence gait piezoelectric signal recognition rate of 86% is achieved by deep learning BiLSTM model. Furthermore, besides expanding the application area of self‐powered system to smart wearable device monitoring, this work also stimulates the evolution of big data analytics in the intelligent medical industry.
Supersensitive Sm2+‐Activated Al2O3 Thermometric Coatings for High‐Resolution Multiple Temperature Read‐Outs from Luminescence
Authors: Ćirić Aleksandar , Stojadinović Stevan , Ristić Zoran , Zeković Ivana , Kuzman Sanja , Antić Željka , Dramićanin Miroslav D. 
Published: March 2021

AbstractThe introduction of additional functionalities to materials is exceptionally important as it opens new applications for them. Aluminum, one of the most abundant and important materials, is coated with luminescent Sm2+‐doped γ‐aluminium oxide to impart thermometric functionality. Considering the potential industrial applications, two of the most widely used aluminum alloys, 6061 and 7075, are also coated. For this purpose, plasma electrolytic oxidation (PEO), an effective technique for producing hard ceramic coatings on various metal surfaces, is used. It is shown that thermometric coatings can be produced on aluminum in one‐step process by adding the raw precursor to the electrolyte. The valence reduction of Ln3+ to Ln2+ is achieved during the PEO process. The intense and broad (orange to deep red) emission from the coating shows supersensitivity to temperature changes over the 100–648 K range. The temperature is obtained from the coating emission using i) the emission intensity ratio method, ii) emission lifetime, and iii) emission band position with sensitivities of 4.8% K−1, 1.2% K−1, and 8 cm−1 K−1, respectively. Several applications would benefit from the thermometric coating's excellent temperature resolution of 0.04 K and the choice of three temperature read‐outs that facilitate the coating's use in different luminescence thermometry setups.
Electrophotocatalytic C−H Heterofunctionalization of Arenes
Authors: Huang He , Lambert Tristan H. 
Published: March 2021

AbstractThe electrophotocatalytic heterofunctionalization of arenes is described. Using 2,3‐dichloro‐5,6‐dicyanoquinone (DDQ) under a mild electrochemical potential with visible‐light irradiation, arenes undergo oxidant‐free hydroxylation, alkoxylation, and amination with high chemoselectivity. In addition to batch reactions, an electrophotocatalytic recirculating flow process is demonstrated, enabling the conversion of benzene to phenol on a gram scale.
One‐step Ethylene Purification from an Acetylene/Ethylene/Ethane Ternary Mixture by Cyclopentadiene Cobalt‐Functionalized Metal–Organic Frameworks
Authors: Wang Yutong , Hao Chunlian , Fan Weidong , Fu Mingyue , Wang Xiaokang , Wang Zhikun , Zhu Lei , Li Yue , Lu Xiaoqing , Dai Fangna , Kang Zixi , Wang Rongming , Guo Wenyue , Hu Songqing , Sun Daofeng 
Published: March 2021

AbstractThe separation of ethylene (C2H4) from a mixture of ethane (C2H6), ethylene (C2H4), and acetylene (C2H2) at normal temperature and pressure is a significant challenge. The sieving effect of pores is powerless due to the similar molecular size and kinetic diameter of these molecules. We report a new modification method based on a stableftwtopological Zr‐MOF platform (MOF‐525). Introduction of a cyclopentadiene cobalt functional group led to new ftw‐type MOFs materials (UPC‐612andUPC‐613), which increase the host‐guest interaction and achieve efficient ethylene purification from the mixture of hydrocarbon gases. The high performance ofUPC‐612andUPC‐613for C2H2/C2H4/C2H6separation has been verified by gas sorption isotherms, density functional theory (DFT), and experimentally determined breakthrough curves. This work provides a one‐step separation of the ternary gas mixture and can further serve as a blueprint for the design and construction of function‐oriented porous structures for such applications.
Designing a Single Protein‐Chain Reporter for Opioid Detection at Cellular Resolution
Authors: Kroning Kayla E. , Wang Wenjing 
Published: March 2021

AbstractMu‐opioid receptor (MOR) signaling regulates multiple neuronal pathways, including those involved in pain, reward, and respiration. To advance the understanding of MOR's roles in pain modulation, there is a need for high‐throughput screening methods of opioids in vitro and high‐resolution mapping of opioids in the brain. To fill this need, we designed and characterized a genetically encoded fluorescent reporter, called Single‐chain Protein‐based Opioid Transmission Indicator Tool for MOR (M‐SPOTIT). M‐SPOTIT represents a new and unique mechanism for fluorescent reporter design and can detect MOR activation, leaving a persistent green fluorescence mark for image analysis. M‐SPOTIT showed an opioid‐dependent signal to noise ratio (S/N) up to 12.5 and was able to detect as fast as a 30‐second opioid exposure in HEK293T cell culture. Additionally, it showed an opioid‐dependent S/N up to 4.6 in neuronal culture and detected fentanyl with an EC50 of 15 nM. M‐SPOTIT will potentially be useful for high‐throughput detection of opioids in cell cultures and cellular‐resolution detection of opioids in vivo. M‐SPOTIT's novel mechanism can be used as a platform to design other G‐protein‐coupled receptor‐based sensors.
Direct Allylic C(sp3)−H and Vinylic C(sp2)−H Thiolation with Hydrogen Evolution by Quantum Dots and Visible Light
Authors: Huang Cheng , Ci Rui‐Nan , Qiao Jia , Wang Xu‐Zhe , Feng Ke , Chen Bin , Tung Chen‐Ho , Wu Li‐Zhu 
Published: March 2021

AbstractDirect allylic C−H thiolation is straightforward for allylic C(sp3)−S bond formation. However, strong interactions between thiol and transition metal catalysts lead to deactivation of the catalytic cycle or oxidation of sulfur atom under oxidative condition. Thus, direct allylic C(sp3)−H thiolation has proved difficult. Represented herein is an exceptional for direct, efficient, atom‐ and step‐economic thiolation of allylic C(sp3)−H and thiol S−H under visible light irradiation. Radical trapping experiments and electron paramagnetic resonance (EPR) spectroscopy identified the allylic radical and thiyl radical generated on the surface of photocatalyst quantum dots (QDs). The C−S bond formation does not require external oxidants and radical initiators, and hydrogen (H2) is produced as byproduct. When vinylic C(sp2)−H was used instead of allylic C(sp3)−H bond, the radical‐radical cross‐coupling of C(sp2)−H and S−H was achieved with liberation of H2. Such a unique transformation opens up a door toward direct C−H and S−H coupling for valuable organosulfur chemistry.
Improved event‐triggered sliding mode control of switched systems with disturbances
Authors: Wang Luyao , Yang Rongni , Zhang Huiyan 
Published: March 2021

AbstractThis paper is devoted to solving the problem of sliding mode control for discrete‐time switched systems with disturbances via an improved event‐triggered strategy. First, the switched sliding mode dynamics is obtained based on the pre‐designed sliding mode surface. Then, on the basis of the Lyapunov functional technique and the average dwell time approach, sufficient conditions for the existence of the concerned sliding mode dynamics are established. Third, the sliding mode control law is synthesized such that state trajectories of the considered switched system can be driven into the bounded sliding mode region and maintain there subsequently. Moreover, the event‐triggered scheme is proposed in close combination with key feature of sliding mode control, which is different from the most existing works. Finally, two examples including a single‐link robot arm system are given to show the effectiveness of the proposed design method.