bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pigeonpea (Cajanus cajan L.) Growth, Yield and Monetary Influence by Drip Irrigation and Mulch in Vertisols of Madhya Pradesh
Authors: Jadav Mohan Lal , Raidas Dhanesh K. , Kumawat Narendra , Girothia O.P. , Bhagat D.V. , Choudhary S.K. 
Published: October 2021

Background: Farmers are facing many constraints related with pigeonpea cultivation therefore proper resources management and scientific practices can increase the production and productivity of pigeonpea. Drip and mulching can be a way to achieve the goal of more crop per drop.
Methods: The field experiments were conducted during kharif season of year 2016-17 and 2017-18. The study area is located (23°16'48'' N-latitude, 77°21'36'' E-longitude) in Madhya Pradesh. The experiment was laid out in vertisols with twenty seven treatment combinations consisting of three mulching, three discharge rate (2 lph-D1, 4 lph-D2 and 8 lph-D3) and three irrigation levels viz. 60% CPE (I1), 80% CPE (I2) and 100% CPE (I3). Well treated bold seeds of pigeonpea (TJT-501) were dibbed in soil on ridge-furrow land configuration. Result: The plant height was maximum in 2 lph (175.78 cm), I2 (176.10 cm) and number of branches, number of pods per plant, seeds per pod also followed the same trend. Maximum yield was registered with D1 (16.48 q/ha) followed by D2 (14.91 q/ha) and D3 (14.46 q/ha). Irrigation level I2 (16.01 q/ha) registered 13.77% higher seed yield than I1 (14.07 q/ha). In case of discharge rate, B:C decreased as rate increased. Among irrigation level treatments, lowest value (1.26) of B:C recorded with 60% CPE whereas highest B:C (1.56) was registered with 80% CPE, which is at par with 100% CPE (1.52). It can be concluded that pigeonpea cultivation is not economical with mulch and 100% supply of irrigation during kharif. It is viable to supply irrigation as per CPE only at branching, flowering and pod development stages.
The place of child development in evaluations related to custody in Turkey
Authors: AYDOS Sebahat , KÖKSAL AKYOL Aysel 
Published: October 2021

The aim of this study is to examine the reports prepared in the process of deciding the custody of children in divorced families in the context of child development. The reports evaluated in the scope of the research were evaluated by the method of document review and the results were found in the context of child development and the best interest of the child. In this context, a total of 107 reports related to custody were examined. The results from findings show that while evaluations regarding custody are expressed in many places with the emphasis on the development of the children, the reports contain little information about the development of the child. When the child's best interest is considered to be the most important component of child development, it is seen that as a result of these depictions, developing a new system in order to protect the best interest of the child, which is one of the top principles of the law related to custody, and carrying out an evaluation that focuses on child development is necessary.
Organization of Six-Cylinder Tractor Diesel Working Process
Authors: Kuharonak G. M. , Klesso M. , Predko A. , Telyuk D. 
Published: October 2021

The purpose of the work is to consider the organization of the working process of six-cylinder diesel engines with a power of 116 and 156 kW and exhaust gas recirculation. The following systems and components were used in the experimental configurations of the engine: Common Rail BOSСH accumulator fuel injection system with an injection pressure of 140 MPa, equipped with electro-hydraulic injectors with seven-hole nozzle and a 500 mm3 hydraulic flow; direct fuel injection system with MOTORPAL fuel pump with a maximum injection pressure of 100 MPa, equipped with MOTORPAL and AZPI five-hole nozzle injectors; two combustion chambers with volumes of 55 and 56 cm3 and bowl diameters of 55.0 and 67.5 mm, respectively; cylinder heads providing a 3.0–4.0 swirl ratio for Common Rail system, 3.5–4.5 for mechanical injection system. The recirculation rate was set by gas throttling before the turbine using a rotary valve of an original design. The tests have been conducted at characteristic points of the NRSC cycle: minimum idle speed 800 rpm, maximum torque speed 1600 rpm, rated power speed 2100 rpm. It has been established that it is possible to achieve the standards of emissions of harmful substances: on the 116 kW diesel engine using of direct-action fuel equipment and a semi-open combustion chamber; on the 156 kW diesel using Common Rail fuel supply system of the Low Cost type and an open combustion chamber.
Use of GPS at research of roads & a vehicle
Authors: Mishuta D. V. , Мikhailov V. G. , Sirai M. V. 
Published: October 2021

The purpose of this work are consideration of use of GPS for a research of roads and modeling of the vehicle/wheel machines (WM).Implementation for this problem of the measuring registering complex on a basis the Raspberry Pi 3/4 minicomputer, the GN-803G sensor and creation of the software in the language C/C ++ is considered.The obtained information about GPS and approaches of selection of necessary data from the messages on the basis of the NMEA 0183 standard submitted in the text ASCII form with the fields divided by a comma is analyzed. An assessment of opportunities of use of the obtained information is given.The scheme of connection of the GN-803N module to Raspberry 3/4 through the GPIO protocol is developed and proved.Reduction of the obtained data to a constant step with use of a polynom of Lagrange of the 2-nd order on three points of a variable step is considered.It is recommended at further use of this corrected data array in process modeling of the car application of a method of interpolation CatMull-Rom on the 4-th points at the fixed step. Program fragments are given in C/C ++.It is offered in the territory of RB during the determining of relative distances and a binding to cards at conversion it is possible to use the simplified linear formula lat_m= 112297,6196∙ Ddec lat , lon_m= 63215,444 ∙ Ddec lon .The offered technique of application of GPS, software, received data are planned to be used for a research of influence of the driver and road conditions on the movement of the vehicle and the subsequent their application when modeling in Matlab/ Simulink, and also in problems of preliminary debugging of management systems by self-driving vehicles.
Antimicrobial Activity, In Vitro Anticancer Effect (MCF7 Breast Cancer Cell Line), Antiangiogenic and Immunomodulatory Potentials of Populus Nigra L. Buds Extract
Authors: Kis Brigitta , Pavel Ioana Zinuca , Avram Stefana , Moaca Elena Alina , Juan Martina Herrero San , Schwiebs Anja , Radeke Heinfried H. , Muntean Delia , Diaconeasa Zorita , Minda Daliana , Oprean Camelia , Bojin Florina , Dehelean Cristina Adriana , Soica Codruta , Danciu Corina 
Published: October 2021

Abstract
Purpose: The aim of this study was to evaluate the antioxidant potential, antimicrobial activity, the in vitro anticancer effect (MCF7 breast cancer cell line), as well as the antiangiogenic and immunomodulatory potential of Populus nigra L. bud (Pg) extract collected from the western part of Romania.Results:Populus nigra L. bud extract presents an important antioxidant activity, due to the rich phytochemical composition. Regarding the biological activity, results have shown that poplar bud extract presents a significant inhibitory activity against Gram-positive bacteria and a dose-dependent decrease of MCF7 tumor cell viability with an IC50 of 66.26 µg/mL, while not affecting healthy cells. Phenomena of early apoptotic events at the maximum concentration tested (150 µg/mL) were detected by Annexin V-PI double staining. The extract induced G0/G1 phase cell cycle arrest. In addition, Pg extract showed antiangiogenic potential on the chorioallantoic membrane. Also, at the highest concentration (150 µg/mL), good tolerability and no signs of toxicity upon vascular plexus were observed. Moreover, in low concentrations, the Pg extract had immunomodulatory activity on primary human dendritic cells by upregulating IL-12 and IL-23 subunits.Conclusion:The study concludes that poplar bud extract elicited antioxidant activity, antitumor properties on the breast cancer cell line, followed by an antiangiogenic effect and an immunomodulatory potential on human primary dendritic cells. The biological activity of Populus nigra L. buds extract may open new directions of research on the topic addressed.
The incidence and localization of arterial Fenestrations of the human brain and their Association to brain aneurysms
Authors: Czyżewski Wojciech , Hoffman Zofia , Korulczyk Patrycja , Torres Kamil , Staśkiewicz Grzegorz 
Published: October 2021

Abstract
The aim of the study was to determine the frequency of occurrence and the most common locations of the fenestration of the cerebral arteries, i.e. developmental anomalies consisting of segmental vessel splitting and also the correlation between their presence and the formation of intracranial aneurysms.
6,545 patients in Independent Public Teaching Hospital No. 4 in Lublin in years 2009-2019 who have undergone the angio-CT examination of the head were retrospectively analyzed. The incidence of vascular fenestration was 0.75%, of which 75% were women and 25% men. Reported vascular anomalies most often occurred in the anterior parts of the circle of Willis – ACA (30.61%), AComA (22.45%) and also in BA (30.61%). It has been shown that the occurrence of different types of fenestrations was similar in the group of men and women. There have been diagnosed 11 cases of intracranial aneurysms among patients with observed fenestration (22.45%). For comparison, the incidence of cerebral aneurysms in Western Europe and the US ranges from 2% to 6%. It leads to the conclusion that among patients with fenestration, this type of vascular anomaly occurs much more often, hence they require more frequent control.
A mHealth-based Nursing Model for the Health Outcomes of the Discharged Patients with Nasopharyngeal Carcinoma: a Pilot RCT
Authors: Liao Tingting , Qiu Liyan , Zhu Jingwen , Li Jiayan , Zhang Yanxin , Yang Li 
Published: October 2021

Abstract
Background: Nasopharyngeal carcinoma (NPC) is the most prevalent cancer in China, accounting for an incidence rate of 12.5/37 in Guangxi, which is the highest in the world. Although chemoradiotherapy offers more effective cancer treatment, it also causes a variety of acute and chronic side effects, seriously affecting the quality of life. NPC has evolved into a chronic disease with most patients opting for home-based rehabilitation. Therefore, efforts on improving the home-based extended care services to improve the quality of life of patients are booming. The Chinese government encourages the use of internet technology for expanding the prospect of nursing. Methods: An experimental design was applied for this study. The study enrolled 116 discharged patients who were re-examined in the Radiotherapy Department of the First Affiliated Hospital of Guangxi Medical University from November 2019 to February 2020. The patients were divided into a test and a control group (n = 58 cases in each group) using the IBM SPSS STATISTICS 20.0 random number generation method. The control group was subjected to routine discharge guidance and follow-up, while the experimental group was implemented with a mobile health (mHealth)-based continuous nursing intervention model. The scores of the side effects, cancer fatigue, and quality of life were compared between the two groups of patients for 3, 6, and 12 months, respectively after discharge from the hospital.Results: This study included a total of 114 patients, and there was no significant difference in the baseline data between the two groups. After 6 and 12 months of intervention, the severity of radiation toxicity and side effects, scores of cancer-related fatigue, and quality of life (symptom field) of the patients in the interventional group were significantly lowered statistically compared to those in the control group.Conclusion: This study is based on the mHealth continuous nursing intervention model, which can better guide discharged patients to master the correct rehabilitation nursing methods, and reduce the side effects of radiotherapy and cancer fatigue.Trial registration: This study was retrospectively registered as a randomized controlled trial in the Chinese Clinical Trial Center. Registration Date: January 12, 2021, Registration Number: ChiCTR2100042027.
A Content Analysis of the Highly-Cited Articles in Medical Education: Commitment to Addressing Change and Reliance On Theory
Authors: Malekahmadi Parisa , Yazdan-Nik Ahmad-reza , Amouzadeh Mohammad , Yamani Nikoo , Compton-Lilly Catherine , Roberts Trudie 
Published: October 2021

Abstract
Background: The medical education community is reflecting increasingly on the role and nature of research in the field. Useful sources of data to include in these reflections are a description of the topics in which we are investing our energies, an analysis of the extent to which there is a sense of progress on these topics, and an examination of the mechanisms by which any progress has been achieved. The purpose of the present study was to provide an insight into the highly cited themes of research into medical education.Methods: This study is a content analysis of highly cited articles in medical education. An in-depth content analysis was conducted, identifying meaning units, which were compacted and coded with labels.Results: During a variety of topics, methods and strategies, 764 codes, 24 descriptive themes, and 7 categories were extracted from the content analysis as the most prominent. Categories for future medical education research were: Modern technology updating in medical education; Learner performance improving; Sociological aspects of medical education; Clinical reasoning; Research methodology concerns of medical education; Instructional design educational models; and Professional aspects of medical education.Conclusions: Medical education is in need of moving to a more theory and discovery driven approach and would profit from broadening its scope and reformation that might bring answers to new concerns. An emphasis on creating more systemic knowledge and theoretical models will nurture the generalizable scientific knowledge and will increase the medical education chance to drive the development of research on learning and instruction.
The Effect of Teaching Clinical Skills Through Social Networks on Nursing Students’ Clinical Skills in Crisis Handling: A Quasi- Experimental Study
Authors: Zaman-hosieni Mohammad , Mirtajaddini Mohamad hasan , Mehdipour-Rabori Roghayeh 
Published: October 2021

Abstract
Background: When a crisis occurs, nurses are at the forefront of providing care to patients in emergency rooms. The need for skilled nurses is increasing due to the crises and disasters that are occurring around the world. The aim of the study was to determine whether teaching clinical skills through social networks can affect nursing students’ clinical skills in crisis handling.Methods: This study was done in Iran in 2021. One hundred nursing students were selected by simple random sampling and divided into control and intervention groups. Nursing clinical skills in crisis questionnaires were used before and after intervention in two groups. Distance learning through social networks was done for a month. SPSS version 15 was used for data analysis. The significance level was 0.05.Results: There was no significant difference between the control and intervention groups before the intervention (P >0.05). The mean score of clinical skills in the control group increased from 60.82 before the study to 62.75 after the study, which was not statistically significant (P >0.05). The mean clinical skills of the intervention group increased from 58.02 before the intervention to 82.52 after the intervention, which was statistically significant (P < 0.001).Conclusions: This study showed nurses’ clinical skills are low during crises. Education through social networks can improve them and should be part of nursing education. The application of this low-cost and inexpensive method is recommended for improving clinical skills in nursing.
Integrating geo-linked electronic health records with neighborhood data to identify place-based barriers for diabetes management in a public healthcare system
Authors: Desai Riya , Nguyen Kim Hanh , Inamdar Pushkar , Rubinsky Anna D. , Hebert-DeRouen Mindy C. , Fields Jessica , Bibbins-Domingo Kirsten , Lyles Courtney R. 
Published: October 2021

Abstract
Background

Despite the body of research on place-based disparities in diabetes, there is room for advancing methods in this space by leveraging multiple datasets, including population census and clinical datasets. Specifically, healthcare systems can leverage geo-linked electronic health records (EHRs) to investigate geospatial clustering and identify social determinants of health.
Methods

We examined geographic clustering of poor diabetes control and corresponding structural and social determinants of health within San Francisco’s safety-net healthcare system. Specifically, we used EHR data to identify individual patient-level addresses and clinical outcomes for diabetes, using hot spot analysis to determine significant hot and cold clusters of diabetes control throughout San Francisco. In addition, by linking patient addresses to public datasets, we described the neighborhood-level conditions associated with hot spots.
Results

Our hot spot analysis showed 18.8% of patients with poor glycemic control (n = 2,126) clustered in hot spots, and 12.8% of patients with controlled diabetes clustered in cold spots. Neighborhoods of patients in hot spots had more Black, Latinx, Native American, and Native Hawaiian or Pacific Islander residents and more residents receiving SNAP benefits, experiencing unemployment, food insecurity, greater rent burden, and low grocery store access.
Conclusions

We present methodological advantages of hotspot analyses utilizing EHR data, as well as the value of combining these approaches with additional public population census data about neighborhood conditions. Moving forward, healthcare systems must partner with public health agencies to utilize EHR data as a means to evaluate structural interventions and eventually target investment in place-based health-enabling resources.
Community Perceptions of a Floodplain Buyout Program in Charlotte, North Carolina
Authors: Cardwell Julia 
Published: October 2021

Abstract
Acquisition of flood risk properties is becoming an increasingly common practice for floodplain risk management. While these buyout programs are often seen as highly effective in achieving their primary goal—reducing flood risk—there are additional variables that should be considered when assessing overall effectiveness of these programs. These variables include equity concerns and post-buyout land use. This study examines the floodplain buyout program in Charlotte, North Carolina with special consideration for these additional variables, including the social variables that may impact the secondary success of floodplain buyout programs. The floodplain buyout program in Charlotte is seen as effective in reducing flood risk, but specific community and neighborhood experience with the buyout program differs significantly. While some communities feel that the flood buyouts were equitable and just, and are able to ascribe land uses to the vacant land that add community value, some communities have differing experiences. The study indicates the continued importance of community-specific examination fof the effectiveness of recovery programs.
Reactivating Hippocampal-Mediated Memories to Disrupt the Reconsolidation of Fear
Authors: Grella Stephanie , Fortin Amanda , Bladon John , Reynolds Leanna , Ruesch Evan , Gross Abby , Shpokayte Monika , Cincotta Christine , Zaki Yosif , Ramirez Steve 
Published: October 2021

Abstract
Memories are stored in the brain as cellular ensembles activated during learning and reactivated during retrieval. Using the Tet-tag system, we labeled dorsal dentate gyrus (dDG) neurons activated by positive, neutral or negative experiences with channelrhodopsin-2. Following fear-conditioning, these cells were artificially reactivated during fear memory recall. Optical stimulation of a competing positive memory was sufficient to disrupt reconsolidation, thereby reducing conditioned fear acutely and enduringly. Moreover, mice demonstrated operant responding for reactivation of a positive memory, confirming its rewarding properties. These results show that interference from a rewarding experience can counteract negative affective states. While interference induced by memory reactivation involved a relatively small set of neurons, we also found that activating a large population of randomly labeled dDG neurons was effective at disrupting reconsolidation. Importantly, reconsolidation-interference was specific to the fear memory. These findings implicate the dDG as a potential therapeutic node for modulating memories to suppress fear.
Characterizing and Quantifying Performance Heterogeneity in Cardiovascular Risk Prediction Models — A Step Towards Improved Disease Risk Assessment
Authors: Kartoun Uri , Khurshid Shaan , Kwon Bum Chul , Patel Aniruddh , Batra Puneet , Philippakis Anthony , Khera Amit , Ellinor Patrick , Lubitz Steve , Ng Kenney 
Published: October 2021

Abstract
Prediction models are commonly used to estimate risk for cardiovascular diseases; however, performance may vary substantially across relevant subgroups of the population. Here we investigated the variability of performance and fairness across a variety of subgroups for risk prediction of two common diseases, atherosclerotic cardiovascular disease (ASCVD) and atrial fibrillation (AF). We calculated the Cohorts for Heart and Aging in Genomic Epidemiology Atrial Fibrillation (CHARGE-AF) for AF and the Pooled Cohort Equations (PCE) score for ASCVD in three large data sets: Explorys Life Sciences Dataset (Explorys, n = 21,809,334), Mass General Brigham (MGB, n = 520,868), and the UK Biobank (UKBB, n = 502,521). Our results demonstrate important performance heterogeneity of established cardiovascular risk scores across subpopulations defined by age, sex, and presence of preexisting disease. For example, in CHARGE-AF, discrimination declined with increasing age, with concordance index of 0.72 [ 95% CI, 0.72–0.73 ] for the youngest (45–54y) subgroup to 0.57 [ 0.56–0.58 ], for the oldest (85–90y) subgroup in Explorys. The statistical parity difference (i.e., likelihood of being classified as high risk) was considerable between males and females within the 65–74y subgroup with a value of -0.33 [ 95% CI, -0.33–-0.33 ]. We observed also that large segments of the population suffered from both decreased discrimination (i.e., <0.7) and poor calibration (i.e., calibration slope outside of 0.7–1.3); for example, all individuals 75 or older in Explorys (17.4%). Our findings highlight the need to characterize and quantify how clinical risk models behave and perform within specific subpopulations so they can be used appropriately to facilitate more accurate and equitable assessment of disease risk.