bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meta-analysis of SNP-environment interaction with heterogeneity for overlapping data
Authors: Jin Qinqin , Shi Gang 
Published: January 2021

AbstractMeta-analysis is a popular method used in genome-wide association studies, by which the results of multiple studies are combined to identify associations. This process generates heterogeneity. Recently, we proposed a random effect model meta-regression method (MR) to study the effect of single nucleotide polymorphism (SNP)-environment interactions. This method takes heterogeneity into account and produces high power. We also proposed a fixed effect model overlapping MR in which the overlapping data is taken into account. In the present study, a random effect model overlapping MR that simultaneously considers heterogeneity and overlapping data is proposed. This method is based on the random effect model MR and the fixed effect model overlapping MR. A new way of solving the logarithm of the determinant of covariance matrices in likelihood functions is also provided. Tests for the likelihood ratio statistic of the SNP-environment interaction effect and the SNP and SNP-environment joint effects are given. In our simulations, null distributions and type I error rates were proposed to verify the suitability of our method, and powers were applied to evaluate the superiority of our method. Our findings indicate that this method is effective in cases of overlapping data with a high heterogeneity.
Spatio-temporal evaluation of the emergency capacity of the cross-regional rain-flood disaster in the Yangtze River Economic Belt in China
Authors: Wang Qian , Chen Junfei 
Published: January 2021

AbstractThis paper assesses the emergency capacity of rain-flood disaster in provinces along the Yangtze River Economic Belt (YREB), China, from 2013 to 2017. In this study, the evaluation index system of emergency capacity on rain-flood disaster was built from the economic-social and environmental-natural aspects, and spatial auto-correlation analysis was used to analyze spatial differentiation characteristics of the emergency capacity. Then, the Spatial Durbin Model (SDM) was used to analyze the influence mechanism of the development level of economic-social factors (ESF) subsystem, environmental-natural factors (ENF) subsystem and the coupling level of these two subsystems on the emergency capacity of rain-flood disaster in provinces. The findings show that the emergency capacity distribution of rain-flood disaster in the YREB presented a “decreasing” spatial pattern of eastern, central and western regions. The development of two subsystems has produced spatial spillover effect and diffusion effect on the neighboring areas. There was a high coupling degree between these two subsystems in the YREB. Although spillover effect existed in space, the spillover did not depend on economic distance.
Application Possibilities of a New Preloaded Nasolacrimal Duct Intubation System
Authors: Mihailovic Natasa , Grenzebach Ulrike H. , Eter Nicole , Merté Ralph-Laurent 
Published: January 2021

Abstract
Introduction The LacriJet (FCI S. A. S. – France Chirurgie Instrumentation, Paris, France) represents a novel, simplified and preloaded system for monocanalicular or monocanaliculonasal nasolacrimal duct intubation. It is a further development of the Masterka and shall reduce the intubation time during the surgical procedure. The aim of the present study was to present first experiences with this system for different indications.
Material and Methods All patients who underwent nasolacrimal duct intubation with the LacriJet at the University of Muenster Medical Center in the period from March to November 2019 were included. The postoperative outcome was evaluated 3 to 6 months later.
Results In total, 12 nasolacrimal duct intubations with the LacriJet were performed at our center in the above-mentioned period. The main indication for intubation was congenital nasolacrimal duct obstruction (CNLDO). In addition, intubation was performed in cases with eye lid tumors involving the nasolacrimal duct, in a case of canalicular laceration and in a case of canaliculitis. In 3 cases, there was an early dislocation or a complete loss of intubation. Of these, 2 were cases with CNLDO and the third dislocation was due to manipulation by the patient. All in all, the functional results were satisfying.
Summary The use of the LacriJet is highly suitable for the treatment of CNLDO, stenting in canalicular laceration or lid tumours involving the lacrimal drainage system. However, the known disadvantages of monocanalicular intubation (dislocation, early loss of intubation) also occur with this type of system and a system briefing seems useful. The LacriJet therefore represents a modern and simple method for nasolacrimal duct intubation and can be used for various indications.
Serum Oxytocin Levels in Patients with Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis and their Association with Disease Activity
Authors: Yukselmis Ozkan , Oktayoğlu Pelin , Caglayan Mehmet , Mete Nuriye 
Published: January 2021

ABSTRACT
Objectives Spondyloarthritis refers to a group of chronic inflammatory diseases that particularly involve the sacroiliac joints and spine but may also have an influence on extra-articular involvement in some patients. Oxytocin is a peptide hormone released from the hypothalamus and stored in the pituitary gland. It is known to have anti-inflammatory effects. The aim of this study was to investigate the serum levels of oxytocin and their potential association with disease activity and spinal mobility in patients with ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nrAxSpA).
Material and Methods Seventy-one patients with nrAxSpA, 38 patients with AS and 67 healthy control subjects were included in this study. Disease activity was assessed by the Bath Ankylosing Spondylitis Disease Activity Index, and spinal mobility by the Bath Ankylosing Spondylitis Metrologic Index. Laboratory examinations included complete blood count, ESR, CRP and oxytocin tests.
Results There was no significant difference in serum levels of oxytocin among the 3 groups (p=0.973). However, serum levels of oxytocin correlated negatively with both ESR (r=− 0.359, p=0.027), CRP (r=− 0.316, p=0.056) and BASDAI scores (r=− 0,448, p=0.005) in patients with AS. On the other hand, serum levels of oxytocin had a negative correlation only with ESR in patients with nrAxSpA (r=− 0.321 p=0.009).Conclusion This study lays the foundation for further studies that may aim to investigate how addition of oxytocin to the treatment regimen impacts on disease activity in patients with AS who exhibit particularly low levels of oxytocin during the active disease period.
Watching without Judging—Genius Awareness Techniques in Homeopathy
Authors: de Laporte Claudia 
Published: January 2021

AbstractHomeopathy is a holistic healing method for diseases of body and mind.Homeopathy and awareness-based healing methods have a lot in common. The important aspects of a mental healing process on the part of the treating person are empathic receptiveness, watching without judging and reflecting of the observed contents. On the part of the patient it is non-judgemental watching, catharsis and integration.The subtle watching of body, emotions and thoughts, applied in homeopathy, is closely related to meditative awareness techniques which nowadays are also used in psychotherapy.The reflection of the observed is done in homeopathy more by the resonant remedy than by words. With this individual remedy we ‘recognise’ our patients and we catalyse a cathartic awareness process. The primary objective of this awareness process is to help the patient understand and to accept himself, as he is, and subsequently to relax.While it is known that many mental disorders improve by becoming aware, this is less known for somatic diseases, although there are many studies which show a mental connection for a great part of physical diseases, and therefore similar techniques should work.The most important link between body and soul is the moderation of stressful and sympathetic states.Only in a relaxed parasympathetic state self-healing and repairing mechanisms and the immune system can work effectively and locomotor tensions get relief.Homoeopaths often deny the awareness-based effects of their healing method, because they fear homeopathy to be reduced to placebo medicine, in a time where homeopathy is attacked from many sides. As everywhere in medicine, the placebo effect is invited to ADD itself to the direct impact of our well-chosen remedies. Let us invite also the awareness effects described above, which are far more than only suggestive, by applying them more specifically.Homoeopaths should be proud of their genius and really holistic art of healing, which bundles substantial, psychic and energetic effects in an economical way and with very low side effects.
Influence of EPs 7630 on Antipyretic Comedication and Recovery from Acute Tonsillopharyngitis in Children: A Meta-analysis of Randomized, Placebo-Controlled, Clinical Trials
Authors: Seifert Georg , Funk Petra , Reineke Thorsten , Lehmacher Walter 
Published: January 2021

AbstractObjective Acute tonsillopharyngitis (ATP) is a common, seasonal infection of predominantly viral origin. Management is aimed at shortening the course of the disease and restoring the comfort of the patient. We performed a meta-analysis to investigate whether treatment with the Pelargonium sidoides extract EPs 7630 reduces the use of antipyretic comedication (i.e., acetaminophen) in children suffering from ATP.Methods Studies were identified from clinical trial registries and medical literature. Randomized, placebo-controlled, clinical trials investigating EPs 7630 in children with ATP and reporting the coadministration of paracetamol were eligible. Based on the raw data of eligible trials, we analyzed cumulative paracetamol use, as well as the ability to attend school at the end of treatment. Three trials including a total of 345 children aged 6 to 10 years and suffering from non-β-hemolytic streptococcal ATP were identified and eligible. Children were administered EPs 7630 or placebo for 6 days.Results Compared with placebo, EPs 7630 reduced the cumulative paracetamol dose by an average of 449 mg (95% confidence interval [CI]: 252–646 mg; p < 0.001). A total of 19.1% (EPs 7630) and 71.5% (placebo) of children were still unable to attend school at the end of the treatment (risk ratio = 0.28; 95% CI: 0.16–0.48; p < 0.001).Conclusion Our meta-analysis demonstrates that EPs 7630 reduced the use of antipyretic comedication and accelerated recovery.
Soilless culture systems.
Authors: Morgan Lynette 
Published: January 2021

Abstract

Soilless cultivation involves growing plants in containers, beds, trays, chambers or channels of a liquid or solid soilless medium. Soilless culture encompasses a wide range of horticultural production methods. These range from potted nursery crops in solid substrates or drip-irrigated greenhouse vegetable crops, to water culture methods. The latter is true 'hydroponics'. In modern times, hydroponics has become the term used to cover many forms of soilless production, both where a solid medium is used to support the plant and where only solution culture is employed.
Seed and seedling delivery systems.
Authors: Morgan Lynette 
Published: January 2021

Abstract

Crop establishment is a fundamental process in horticultural production. Seed and seedling delivery systems vary considerably between different types of crops, growing situations, and with level of mechanisation available. Large scale commercial crops are largely reliant on fully automated methods of both seeding and transplanting, but smaller scale operations may only use manual labour, or in combination with low technology automation.
Transcranial direct current stimulation and repeated sprint ability: No effect on sprint performance or ratings of perceived exertion
Authors: Alix‐Fages Carlos , Romero‐Arenas Salvador , Calderón‐Nadal Giancarlo , Jerez‐Martínez Agustín , Pareja‐Blanco Fernando , Colomer‐Poveda David , Márquez Gonzalo , Garcia‐Ramos Amador 
Published: January 2021

ABSTRACTThe role of transcranial direct current stimulation (tDCS) as an ergogenic aid is receiving attention from scientists to optimize sport performance. Most studies have examined the effects of tDCS on endurance performance during continuous tasks, while the effect of tDCS on high‐intensity intermittent tasks has been less investigated. Therefore, this study aimed to explore the acute effects of tDCS on sprint performance and ratings of perceived exertion (RPE) during a repeated sprint ability (RSA) task. Twenty‐five healthy males (age: 22.0 ± 2.5 years) participated in a randomized crossover study consisting of three experimental sessions (anodal, cathodal or sham tDCS) separated by 1 week. Each session consisted of (I) tDCS protocol (15 min at 2 mA applied over the dorsolateral prefrontal cortex [DLPFC]), (II) warm‐up and (III) RSA task (ten 30‐m running sprints separated by 30 s). Total time and RPE values were recorded for each sprint. The two‐way ANOVA applied on sprint time did not reveal a significant main effect of tDCS condition (p = .200) neither a significant tDCS condition × number of sprint interaction (p = .716). Similarly, no significant differences were observed for the fatigue index (p = .449), RSAmean (p = .200) or RPE after each sprint (p range = .116–.890). The magnitude of the differences between the tDCS conditions ranged from negligible to small (effect sizes ≤ 0.33). These results suggest that the application of tDCS over the DLPFC is not effective to increase sprint performance or reduce RPE during a RSA task.HIGHLIGHTS
Transcranial direct current stimulation (tDCS) is a non‐invasive brain stimulation technique that could modulate neuromuscular performance.
This study aimed to explore the short‐term effects of tDCS on sprint performance and ratings of perceived exertion (RPE) during a repeated sprint ability (RSA) task.
The application of either ANODAL or CATHODAL tDCS over the DLPFC for 15 minutes did not affect the sprint time of single repeated sprints or the overall metrics of RSA performance (RSAmean and fatigue index).
The application of either ANODAL or CATHODAL tDCS over the DLPFC for 15 minutes did not affect the ratings of perceived exertion measured during the repeated sprints task.
Numerical simulation of the soliton solutions for a complex modified Korteweg–de Vries equation by a finite difference method
Authors: Xu Tao , Zhang Guowei , Wang Liqun , Xu Xiangmin , Li Min 
Published: January 2021

Abstract
In this paper, a Crank–Nicolson-type finite difference method is proposed for computing the soliton solutions of a complex modified Korteweg–de Vries (MKdV) equation (which is equivalent to the Sasa–Satsuma equation) with the vanishing boundary condition. It is proved that such a numerical scheme has the second-order accuracy both in space and time, and conserves the mass in the discrete level. Meanwhile, the resulting scheme is shown to be unconditionally stable via the von Nuemann analysis. In addition, an iterative method and the Thomas algorithm are used together to enhance the computational efficiency. In numerical experiments, this method is used to simulate the single-soliton propagation and two-soliton collisions in the complex MKdV equation. The numerical accuracy, mass conservation and linear stability are tested to assess the scheme’s performance.
Study of K*(892)0 and ϕ (1020) meson production in proton–proton and Pb–Pb collisions at

sNN

= 2.76 TeV
Authors: Ali Y , Ahmed M , Arif A , Ali Q , Tabassam U , Rubab U , Suleymanov M 
Published: January 2021

Abstract
In this paper, we describe a study of charged particle yield as a function of p

T
for K
*(892)0 and ϕ (1020) mesons in proton–proton (pp) and Pb–Pb collisions at

s

N
N

= 2.76 TeV in the central rapidity region of ∣y∣ < 0.5, in a p

T
range of 0 < p

T
< 15 GeV c
−1 in pp collisions and in a p

T
range of 0 < p

T
< 20 GeV c
−1 in Pb-Pb collisions. We also investigated a very important ratio, the nuclear modification factor, to study the effects of the medium in the most central region, i.e. 0%–5% centrality. For data simulation, we used the EPOS-LHC and EPOS-1.99 models. To check the validity of these models’ simulations, we compared the data obtained from these Monte Carlo simulation programs with ALICE experimental data for

s

N
N

= 2.76 TeV. It was concluded that the models’ predictions for the ϕ-meson in pp and for the most central Pb-Pb collisions disagreed with the ALICE data, and that the difference increased with p

T
. This may be connected with the essential role of collective parton behaviors which could not have been taken into account by the models. For K
*0 mesons, both programs gave almost the same predictions, and with p

T
in the interval p

T
> 3 GeV c
−1, the predictions were very close to the experimental data. Both models gave higher predictions for the soft p

T
interval and lower predictions for the hard interactions. The values of the R
AA distributions were lower than unity and both models were very close to the ALICE data. It is very interesting that the models were not able to describe the p

T
distributions, but they gave good predictions for their ratios. This may possibly be due to parton collective behaviors. We observed some additional suppression of K
∗0 at low values of p

T
with respect to ϕ-mesons, which may be related to the role of the masses of the particles in soft interactions. The rising trend for R
AA in the region from p

T
= 10 GeV c
−1 to 20 GeV c
−1 observed by the ALICE experiment was absent for the ϕ-mesons.
α-decay study of 218Ac and 221Th in 40Ar+186W reaction *
Authors: Hua Wei , Zhang Zhiyuan , Ma Long , Gan Zaiguo , Yang Huabin , Huang Minghui , Yang Chunli , Zhang Mingming , Tian Yulin , Zhou Xiaohong , Yuan Cenxi , Shen Caiwan , Zhu Long 
Published: January 2021

Abstract
In this study, 218Ac and 221Th nuclides were produced via the heavy-ion induced fusion evaporation reaction 40Ar + 186W. Their decay properties were studied with the help of the gas-filled recoil spectrometer SHANS and a digital data acquisition system. The cross section ratio between 222Pa and 218Ac was extracted experimentally, with measured value 0.69(9). Two new possible α decay branches to 221Th are suggested. The valence neutron configurations for the daughter 217Ra are discussed in terms of the hindrance factors.
The 15th SIAM PHYSICS CONGRESS (SPC2020)
Authors: Soonthornthum B , Aukkaravittayapun S , Kittara P 
Published: January 2021

The 15th Siam Physics Congress (SPC2020) was successfully held online during June 4–5, 2020. Initially, the Thai Physics Society with Mahidol University and Prince of Songkla University had planned to co-host the SPC2020 in Trang province in Southern part Thailand. Unfortunately, due to the coronavirus (COVID-19) pandemic throughout many countries all over the world and also in Thailand, the organizing committee had seriously considered this unexpected, serious and intense crisis on the health issue. Therefore, there came a decision that the congress should not be held physically, but the congress should instead utilize online internet connections through hubs hosted at the Thai Physics Society and its co-hosts. This is to keep up to the highest standard of health regulation and self-practice (from WHO) in avoiding the extremely serious pandemic. Consequently, the Thai Physics Society, Mahidol University and Prince of Songkla University had facilitated and hosted the SPC2020 as national teleconference during June 4–5, 2020.
List of titles Track(Session), Organizing Committee, Scientific Committee, Editorial Committee, Plenary Speakers, Organizing Institutions, Sponsors are available in this pdf.
Characteristic of Fe in tektite observed from XANES and UV-Vis spectroscopy
Authors: Paisarnsombat S , Monarumit N , Aimploysri S 
Published: January 2021

Abstract
Tektite is a geological sample formed as a result of a collision of the meteorite on the surface. An energy from the collision results in an excavation of the melted material into the Earth’s atmosphere and landed back on the surface further away from the impact site having glassy or crystalline textures. Tektite was deposited in Thailand and was identified as part of the Australasian strewn field. Chemical compositions of tektites have previously been studied. However, there is no study has established a relationship between composition and color of tektites. Thus, this study aims to relate the characteristic of color-center element, Fe, to the color of tektites using X-ray Absorption Near Edge Structure (XANES) and UV-Vis spectroscopy. Nine tektite samples were collected from Korat plateau and purchased from Thailand and Vietnam gem markets. XANES spectra of all (nine) samples show similar Fe K-edge pattern with pre-edge and E0 at 7080-7089 and 7118 eV, respectively. The spectrum is 100 percent matched with XANES structure of FeO standard suggesting Fe component of Fe2+ oxidation state in the sample. Seven, out of nine, samples establish similar UV-Vis broad absorption peak at 492-539 nm, which corresponds to absorption peak of Fe2+. The UV-Vis absorption spectrum cannot be obtained from two samples possibly due to high Fe-content in the samples. The calculated energy band gaps (E

g
) of the samples are in between 1.35 eV to 1.76 eV with maximum absorption in between 1.88 eV to 1.95 eV. The result is in consistent with a black color of the tektite. It indicates that cause of color in tektites is related to Fe-content and can be explained by the energy band. This study can be furthered compare with moldavite (green variety of tektite) in order to identify cause of color in impact-related materials like tektites, as well as to provide information for identification of synthetic and genuine moldavites and also for characterization of tektites sources using the component of various Fe oxidation states.
Constraints on dark matter annihilation from several IACTs’ cosmic ray electron spectrums
Authors: Duangchan Chaimongkol , Wechakama Maneenate 
Published: January 2021

Abstract
In dark matter self-annihilation events, highly energetic electron and positron pairs can be created in several different annihilation channels and propagate through space while losing their energies. The electrons can lose their energies by these mechanisms; the interaction with low-energy photons via inverse Compton scattering, synchrotron radiation due to interstellar magnetic fields, and ionization with neutral hydrogen atoms, resulting in high energy cosmic electron fluxes at the Earth’s location. Adopted electron spectrums from H. E. S. S., MAGIC, and VERITAS which are Imaging Atmospheric Cherenkov Telescopes (IACTs), we have found the constraints on dark matter annihilation in a range of TeV energies. The results show the stringent constraint on electron channels, and there are no significant differences in constraints between IACTs’ data sets.
A global view of stellar populations in M82
Authors: Suwannajak C , Duangphumek S 
Published: January 2021

Abstract
We present photometric and spectroscopic studies of the stellar content of M82, including the resolved halo stellar population and the halo globular clusters. M82 is a nearby peculiar galaxy that recently went through a close encounter with its more massive companion, M81. As a result, M82 has a high star formation activity and unusual stellar content. We studied the resolved stellar population using the imaging data from the Hubble Space Telescope (HST) data archive. Then, their metallicities were analyzed to understand a global view of the stellar populations in M82. We found that the old stellar population in M82 shows typical characteristics for a disk galaxy, while the young stellar population shows a sign of disruption as a result of the recent interactions.