bluuebunny/crossref_metadata_2025_split huggingface dataset:
Micro-Anatomical Characterization of African Native Monotypic Genera - Anogeissus (DC.) Guill and Quisqualis Linn (Combretaceae)
Authors: Akinsulire Opeyemi Philips , Oladipo Olaniran Temitope , Akomolede Aderemi Lucas 
Published: July 2021

Abstract
This study was designed to explore the micro-anatomical characteristics of leaf and petiole of two unstudied West African native monotypic genera - Anogeissus and Qusqualis in Combretaceae with a view to characterizing the taxa, providing useful research-based information for identification. The samples were prepared following standard procedures. The light microscopic study of the transverse sections of the leaves in A. leiocarpus revealed a thick upper and lower cuticle while the cuticle on both leaf surfaces in Q. indica remain thin. The midrib vascular bundle of the leaf in Q. indica is characterized by arc-shape and starch grains were observed in the parenchyma cells of the ground tissue. The uniseriate rows of lamina epidermis were oval, squared, rectangular or polygonal in Q. indica while it was rectangular or slightly oval in A. leiocarpus. Vascular bundle in the leaves and petioles of both taxa were collateral. Simple, slender and short unicellular non-glandular trichomes were also observed in the leaf and petiole micro-anatomy of both taxa. It was concluded that the micro-anatomical features of the leaves and petioles are important parameters of characterization, used in the identification of the studied taxa.
Does body mass index have an effect on the prevalence of various symptoms of polycystic ovary syndrome and their associated risk factors?
Authors: Kaur Raminder , Kaur Maninder , Suri Vanita 
Published: July 2021

The present cross-sectional study is an attempt to understand the effect of body mass index (BMI) on the prevalence of various symptoms of polycystic ovary syndrome (PCOS) and to evaluate its associated risk factors.
A total of 250 PCOS women diagnosed by Rotterdam Criteria (2003), age ranging from 18–45 years, attending OPD of Gynaecology and Obstetrics of PGIMER, Chandigarh, India were enrolled in the study. All the participants were divided in three groups according to their body mass index (BMI). The polycystic ovaries (83.2%) were the most frequently occurring symptoms of PCOS followed by hirsutism (74.4%), oligomenorrhea (60%), seborrhea (45.2%) and acne (40%). Category wise frequency distribution showed higher prevalence of symptoms among women in overweight/obese category, which were further supported by correspondence analysis. Results of multivariate analysis revealed that marital status, type of diet, socio-economic status and physical activity level were potential risk factors contributing to severe manifestations of PCOS symptoms.
Obesity denoted as an important risk factor can exaggerate many symptoms of PCOS and also be a causative factor for menstrual disturbance.
Complex Polypathology Infectious, Rheumatological, Neurological and Orthopedic – Real Challenge for Functional Rehabilitation - Case Report
Authors: Cristiana Libu , Gabriela Iliescu Mădălina , Maria Bobe Zoe , Cristina Arghir Oana , Dana-Maria Bilous , Ana-Maria Ionescu , Bogdan Obadă , Irina Albadi , Doinita Oprea 
Published: July 2021

Abstract
Introduction. Infectious and autoimmune rheumatic diseases (ARDs) are closely linked. Apart from the challenging, sometimes differential, diagnosis between these conditions, it is recognized that microbes play an important role in the pathogenesis of the latter. Material and method. We present the case of a 45-year-old female patient from our rehabilitation department, with complex pathology (infectious, neurological, rheumatological and orthopedic pathology) that began more than 15 years ago. The patient’s pathological history began insidiously at theage of 30 when she was diagnosed with neurotoxoplasmosis. She received anticoagulant, antiepileptic, steroidal, antibiotic and antihelmintic treatment. After four years, the patient shows insidious onset of inflammatory pain in the large joints and in 2010 is diagnosed with seropositive rheumatoid arthritis, according to American College of Rheumatism/European League against rheumatism (ACR/EULAR) criteria with symmetric impairment of the large joints (shoulder, elbow, hip, knee, ankle). Despite the treatment with disease-modifying anti-rheumatic drugs (DMARDs) received, in the following years she needed 4 arthroplasties in the large joints due to osteonecrosis. Conclusions. On clinical grounds, infections, especially chronic infections, can cause a plethora of autoimmune phenomena, thus mimicking ARDs. Therefore, the differential diagnosis between ARDs and infectious diseases is sometimes challenging as they often display similar clinical manifestations. It is highlighted that the immune system can be our friend or our foe considering that its function and dysregulation are the common denominators in autoimmune and infectious diseases. In the era of new drugs and new therapeutic strategies, safety of the patients should always be our first concern.
Effects of flattening filter (FF) and flattening filter-free (FFF) beams on small-field and large-field dose distribution using the VMAT treatment plan
Authors: Plaza Dominika J. , Orzechowska Klaudia M. , Ślosarek Krzysztof T. 
Published: July 2021

Abstract

Introduction: The aim of the study was to evaluate the influence of flattening filter (FF) and flattening filter-free (FFF) beams on small-field and large-field dose distribution using the VMAT treatment plan.

Material and methods: Dose distribution calculations were performed for the VMAT technique in two locations: the larynx (small irradiation field; average 30.1 cm2) and gynecology (large irradiation field; average 173.1 cm2) using X-6MV flattening filter (FF) and flattening filter-free (FFF) beams. The following values were compared: the number of monitor units, minimum doses, average doses in PTV and maximum average doses in OaR (spinal cord – in larynx radiotherapy, bladder and rectum - in gynecological radiotherapy) and RPI (Radiation Planning Index) coefficient.

Results and Discussion: The performed statistical tests indicate that there is a significant difference (p <0.05) between the number of monitor units in the irradiation of large (gynecological) fields between the FF and FFF beams. The dose distributions show no statistically significant differences between the flattening filter and flattening-free filter beams (regardless of the field size).

Conclusions: Due to the smaller number of monitor units, it is recommended to use flattening filter beams (FF) for large-field radiotherapy.
Sustainable Tourism as a Driving Force in Regional Development of Remote Regions in Siberia: An Integrated Operational Framework
Authors: Vitálišová Katarína , Borseková Kamila , Blam Inna 
Published: July 2021

Abstract
Regional development based on sustainable tourism is one of the options of developing remote regions, which are usually disadvantaged due to their distance, but can have a certain competitive advantage based on their remoteness. The present paper offers in-depth analysis of the tourism potential in selected remote regions of Russia, the Altai Mountains and Lake Baikal with the aim to explore the specific features of their sustainable tourism development and to propose an integrated operational framework for sustainable tourism and regional development usable for similar regions across the world. The proposed integrated operational framework helps to achieve a tricky balance between economic resurrection of remote areas and environment conservation, which is possible only with the proper co-integration of tourists with the community, and local economic development with the environment. It presents a set of drivers and their mutual relations to achieve the successful sustainable tourism development in remote regions in Russia and across the world. The present research results contribute to a knowledge bank that could serve as a useful guide for academics and policymakers involved with sustainable development, geography or environmentally sensitive tourism.
FE Analysis of the Symptomatic Navicular - A Case Report
Authors: Prodanovic Nikola , Savic Suzana Petrovic , Ristic Branko , Jovanovic Zoran , Radivojcevic Uros , Stepanovic Zeljko , Kolak Djordje , Andric Kristina , Prodanovic Tijana , Stojanovic Bojan , Andric Nikola 
Published: July 2021

Abstract
The accessory navicular (AN) is a bony formation located on the medial side of the foot, proximal to the navicular and continuous with the posterior tibialis tendon. It emerges as a developmental variant due to the presence of the secondary ossification center adjacent to the primary center of the navicular. It is regarded as a physiological and anatomical variant. In most instances, this is an incidental finding. Radiographic values are used to define three types of AN based on its relationship with the navicular. The symptomatic AN causes pain in the medial portion of the bone, a decreased range of motion and discomfort with shoe wearing. In case of recurrent symptoms, following an inadequate diagnosis and treatment, it can result in acquired flatfoot. Our case study examined the condition of asymptomatic AN in a young man with both flatfeet, who was initially treated conservatively, and then, after the failed response to the therapy, surgically. Following the Kidner procedure (excision with the reattachment of the insertion in the posterior tibialis tendon) and rehabilitation, the patient reports no subjective symptoms in the period of 12-month monitoring. An objective examination was conducted with the use of FE analysis during weight-bearing. We determined a reduction in total weight-bearing and the pressure distribution to the lateral side of the foot, metatarsal, and the heel region.
Estimating Emissions of Harmful Exhaust Components by Aircraft Engines During the Takeoff and Landing Cycle in Airport Space
Authors: Głowacki Paweł , Kalina Piotr , Kawalec Michal 
Published: July 2021

Abstract
This article examines, based on the available information and authors’ self-assessments, the environmental impact of turbine engine exhaust gases effect on the environment in the airport space during engines flight phases in the landing and takeoff cycle (LTO). The attention of aviation professionals is drawn to the fact that the amount of exhaust from the turbine engine is so significant that it may adversely change the ambient air at the airport. Consequently, increased emission level of carbon monoxide (CO), hydrocarbons (HC) during engine start-up and idle may pose a threat to the health of ramp staff. Also, high emission levels of nitrogen oxides (NOx) during takeoff, climb, cruise and descent is not without importance for the environment around the airport space. The paper gives CO2, HC, CO and NOx emission estimations based on ICAO Engine Emission Data Bank and the number of passenger operations at a medium-sized airport. It also provides calculation results of aircraft CO2, HC, CO and NOx emission using average times of aircraft maneuvers taken from aircraft Flight Data Recorder (FDR) in the LTO cycle various aircraft types at the airport. The latter, based on actual maneuvering times, lead to significantly reduced estimates of toxic exhaust gas emission volumes.
The study of the theoretical approaches to the event management in order to form the brand of a higher education institution
Authors: Kotvitska A. A. , Yakovlieva O. Yu. 
Published: July 2021

Aim. To study the features of the events held by the institution of higher education and their impact on the formation of a positive image of the institution.
Materials and methods. The following research methods were applied: theoretical (analysis and synthesis of scientific literature and normative sources, generalization, classification, analytical, comparative and logical), empirical (description, comparison). The scientific data and normative documents concerning events and the system of branding formation of a higher education institution were used.
Results. The study of scientific papers on the event management and event marketing has been conducted. The meaning of the concept of “event” has been defined. The goals and objectives of events held in the educational space have been formulated. The types of events have been studied. The main types, content and examples of events that are advisable to hold in a higher education institution are given: informational, scientific, festive, socio-cultural, image-making. Such criteria for classification of events as openness of events, the number of the audience involved, types of the tasks performed, goals of the event, the audience involved and directions of work of a higher education institution have been proposed. The principles of a “successful event” of a higher education institution have been defined. The stages of organizing events of a higher education institution have been proposed. The expediency of conducting a survey after the event has been determined in order to identify the advantages and disadvantages of the event, form the purpose of attending the event by different participants, improve the quality of events and determine the impact on the image of the institution.
Conclusions. The stages of the event management in higher education institutions have been suggested. The meaning of events has been defined; their objectives, tasks and classification, have been determined. The principles of the event organization, factors that determine the effectiveness of events and the advantages of events as marketing communication tools have been formed.
Situation Analysis of the Drug Registration in Vietnam from 2009 To 2019
Authors: Thi Hai Yen Nguyen , Ngan Thai Hue 
Published: July 2021

Vietnam is classified into the group of emerging pharmaceutical countries (Pharmerging) according to the classification of IMS Health since 2008. In order to achieve the potential, it is necessary to have a clear understanding of the status of drugs registered for circulation in Viet Nam. However, research on this issue has not been popular, lacked updating, and has not shown continuous change over a long period of time. Therefore, the study is conducted with the desire to provide an overview of the status of drug registration in Vietnam in the period 2009-2019. Classify "Drugs" according to the Law on Pharmacy No. 105/2016/QH13. Pharmaceutical and biological drugs are classified into 27 groups according to ATC codes based on Circular 30/2018/TT-BYT and Vaccine. 19 groups of dosage forms, classified according to the Vietnam Pharmacopoeia V. In the period 2009-2019, Vietnam has 45,801 registered drug registration numbers. In which, domestic drugs with 28,388 numbers (62%). India and South Korea are the 2 countries with the most number of registrations, accounting for 33.9% and 17.3% respectively. Chemico-pharmaceutical finished products registered with 42,245 numbers (92.2%). The group of drugs for treating parasites and anti-infections is the most registered with 27.1%. Oral and parenteral administration, infusion are the two main forms of administration, of which tablets are the most registered dosage form, accounting for 46.4%. Paracetamol is the most registered active ingredient with a total of 2262 registration numbers. Drugs produced domestically have partly met the needs of the people to use drugs, but there is still an imbalance between the pharmacological groups and registered active ingredients. Domestic pharmaceutical enterprises need to increase investment in and research active ingredients and drug groups with few registered numbers.
Keywords
Drug registration number, active pharmaceutical ingredient, drug registration, period of 2009-2019, Vietnam.
References
Features of metropolitan area governance models
Authors: Pavlov Yu. V. , Khmeleva G. A. 
Published: July 2021

The article develops a methodological basis for choosing the optimal model for managing the agglomeration of settlements. The existing agglomeration problems and the need to accelerate growth due to the agglomeration effect form a challenge to the agglomeration governance system. For an adequate response it is important to understand the capabilities of governance models. These capabilities can be expressed through the description of the features of the models.For a large-scale description of the features of models, it is necessary to form groups of features, characterize each feature, compare the models according to the degree of its manifestation, and, if possible, explain the reason for the differences. The article investigates research papers within the framework of the theory of municipal reformers, the theory of public choice, in particular on the issues of centralization / decentralization of municipalities, intermunicipal cooperation, the efficiency of the economy of the public sector. The authors used general scientific methods of analysis, synthesis, grouping, comparison.The revealed features make it possible to assess the governance model in terms of what the agglomeration will receive from its implementation. All features are combined into five groups: economic, social, administrative efficiency, democratization, stability. The study revealed 29 features, presented their explanation and degree of development, depending on the type of governance model.As a result of the study, the possibilities for justifying the feasibility of introducing models have increased. The authors represented scientific novelty by a more complete list of the features of models, a more detailed presentation of them, the approach of presenting information “from features”, a convenient grouping that allows you to use the characteristic to assess the effectiveness of the activities of government authorities. The study can be useful for civil servants in charge of agglomeration processes.
Business strategy design methodologies: from product design to platform design
Authors: Vasilieva E. V. 
Published: July 2021

The article presents an analysis of modern methodologies that are successfully used for the development of innovative products and ecosystem platforms. The paper describes the tools of the “Jobs To Be Done” approach. The author highlights the differences between the two concepts “Jobs-As-Activities” and “Jobs-As-Progress”. The study emphasizes the importance of studying the digital client path. The publication presents by step-by-step an algorithm for constructing a strategy for bringing a new offer to the market based on the “Jobs To Be Done” method. The article presents examples of filling in the Job stories Canvas, interview framework in “Jobs To Be Done” format, Process Making Forces Canvas.The study shows the tools that are successfully used in creating a business strategy based on an ecosystem platform. The paper substantiates the importance of customer-oriented approach and switching to an ecosystem approach to the development of a business model. The author highlights the benefits from the ecosystem of the user, business owner and partners.The study gives an overview of ecosystem types according to the Gartner classification with examples in Russian ecosystems. The author provides tools of the Platform Design (Platform Innovation Kit) which allow you to develop an integrated environment for the development of the customer experience, to improve consumer goods and services: VRIO framework, a Matrix of Motivation, the Ecosystem Platform Relations Canvas, Training Mechanism Canvas, Value Proposition Canvas and Platform Business Models Canvas. These tools expand the design thinking portfolio.
Synthesis, Characterization And Assessment of Anti Microbial Behaviour of Goat Faecal Mediated Silver Nanoparticles- Fed on Tirumala Hills
Authors: Shakir Basha S  , Ashok Thulluru  , Naresh Babu C  , Chithra Shekar C  , Jagadeesh P  , Mohammed Idress N S  , Praveena R  , Sravan Kumar C  , Anil A  
Published: July 2021

To synthesize, characterize, and to assess the anti-microbial activity of silver nanoparticles (AgNPs) induced by goat fecal matter. The AgNPs were processed by the microwave heating method and the characterization was accomplished by employing various spectroscopic approaches such as UV-Visible, FTIR spectroscopy, XRD, Particle size, and Zeta potential analysis. The lmax for both extracts were found at 426& 438nm. The wideband corresponded to O-H stretching vibrations at 3384.0 cm-1, 3273.9 cm-1 and 3366.2 cm-1, bands at 2918.5 cm-1, 2922.5 cm-1, 2853.2 cm-1, and 2850.2 cm-1 corresponded to the N–H and C–H stretching. The bands at 1638.1 cm-1, 1651.9, and 1686.5 cm-1 corresponded to the C=C stretch. Bands of 1460.3 cm-1, 1450.4 cm-1, 1409.2 cm-1 and 1376.3 cm-1 corresponded to C-N, C-C bond stretching vibrations. The stretch of C-O indicates bands at 1159.7 cm-1, 1033.2 cm-1, and 1032.8 cm-1. The synthesized AgNPsdemonstrated good anti-microbial activity on gram +Ve (S.aureus) and gram -Ve (E.coli) bacteria. Bio/Green synthesized AgNPs have shown improved biological performance, this tends to minimize production cost, pollution-free, less chemical usage, and stable generation of nanoparticles.
Desafios para a realização de Pesquisas Educacionais
Authors: Ferreira Teixeira Cauê , Pires André , Renda Vitorino Artur José 
Published: July 2021

Pesquisas e planejamentos educacionais têm esbarrado em inúmeras dificuldades, principalmente metodológicas, para desenvolver-se. Neste artigo, discutiremos as dificuldades existentes em pesquisas educacionais referentes Ã linguagem, Ã s relações entre a pedagogia e as outras ciências humanas, aos riscos do abstracionismo pedagógico, aos desafios para que a Pedagogia estabeleça uma metodologia própria e Ã postura do pesquisador ante seu objeto, que constantemente constitui-se como outro sujeito. Objetivamos, assim, contribuir para reflexões acerca da importância do desenvolvimento de pesquisas educacionais que não enveredem por um abstracionismo pedagógico, tampouco por um teoricismo vago.
O congado vai para a escola e a escola vai para o congado
Authors: Fonseca Marcus Vinícius , Siqueira Silva Fabiana 
Published: July 2021

Nesse artigo apresentamos aspectos ligados Ã uma experiência singular envolvendo o congado e a escola que ocorre na Associação dos Pais e Amigos dos Excepcionais de Ouro Preto (APAE-OP), onde surgiu um grupo de congado como parte de um projeto pedagógico e se firmou como elemento de culto Ã Nossa Senhora do Rosário. Analisamos essa experiência através de um estudo de caso que procurou caracterizar o congado em Ouro Preto, sua emergência dentro da escola e seus desdobramentos pedagógicos. Procuramos destacar a singularidade dessa experiência demonstrando como ela está relacionada com a dinâmica de uma cidade onde a cultura negra se manifesta com intensidade.
PENGARUH LIKUIDITAS, PROFITABILITAS, UKURAN PERUSAHAAN, KOMISARIS INDEPENDEN TERHADAP AGRESIVITAS PAJAK DAN PENGUNGKAPAN CSR SEBAGAI MODERASI
Authors: Erlina Magdalena 
Published: July 2021

This study aimed to analyze the effect of liquidity, profitability, firm size, independent commisioner toward tax aggressiveness and moderated by corporate social responsibility (CSR) disclosure in Indonesian mining companies listed on Indonesian Stock Exchange (IDX). This research used quantitative approach with descriptive and verification method. A sample of companies using purposive sampling technique and research data comes from financial reports, annual reports and annual reports of CSR disclosure of mining companies listed on the IDX and published in the period 2018-2019. Partial least square (PLS)-Structural Equation Model (SEM) was used as the method of analysis to examine the effect of the above variables supported by SmartPls 3.0 software system. The results shows that partially profitability affect significantly toward tax aggressiveness. However, liquidity, firm size, and independent commissioner have no partial effect on tax aggressiveness. As for the moderating effect, the result also shows that CSR disclosure does not significantly affect to strengthen or weaken the correlation between liquidity, profitability, firm size and independent commissioner toward tax aggressiveness.
Keywords: Liquidity, Profitability, Firm Size, Independent Commissioner, CSR Disclosure, Tax Aggressiveness