bluuebunny/crossref_metadata_2025_split huggingface dataset:
Female Genital Mutilation/Cutting in the Swiss HIV Cohort Study: A Cross-Sectional Study
Authors: Mauri Fabio , Cottler-Casanova Sara , Cavassini Matthias , Stoeckle Marcel , Wandeler Gilles , Schmid Patrick , Braun Dominique L , Scherrer Alexandra , Bernasconi Enos , Calmy Alexandra , Abdulcadir Jasmine 
Published: November 2021

Abstract
BackgroundFemale genital mutilation or cutting (FGM/C) is the practice of partial or total removal or injury of the external female genitalia for non-medical reasons. It has been documented in at least 30 countries and, as a result of migration, in high-income countries too. FGM/C causes various negative health complications, and may increase the risk of acquiring human immunodeficiency virus (HIV).Our study aims to generate descriptive statistics about FGM/C among HIV positive migrant women included in the Swiss HIV cohort study (SHCS).MethodsThe Swiss HIV Cohort study (www.SHCS.ch) is a national, prospective cohort study with ongoing community and hospital enrolment of HIV-positive individuals in Switzerland. Two questions on history of FGM/C and previous discussion about it with a healthcare professional were administered by treating infectious disease specialists during the 6-monthly routine visits occurring between June and December 2019. We included all women aged above 18 years, born in one of the 30 countries where FGM/C is prevalent, in care for an HIV-infection and recorded in the Swiss HIV Cohort Study.ResultsOur findings show that FMG/C is common (21%) in the SHCS female population originating from Africa. Such data may be largely underestimated given the 33.6% of non-respondents. The vast majority (70%) of the women reporting to have been cut had never discussed FGM/C with a health professional before the study.Conclusions FMG/C is common in the SHCS female population originating from Africa, but often overlooked by health professionals working with this population. FGM/C screening, diagnosis, care and prevention could be improved significantly through training and information.Trial registration: Not Applicable
Developmental brain structural atypicalities in autism: A voxel-based morphometry analysis
Authors: Wang Hui , Ma Zeng-Hui , Xu Ling-Zi , Yang Liu , Ji Zhao-Zheng , Tang Xin-Zhou , Liu Jing-Ran , Li Xue , Cao Qing-Jiu , Liu Jing 
Published: November 2021

Abstract
Background
Accumulating structural Magnetic Resonance Imaging (sMRI) studies have showed atypicalities in developmental changes of structural regional brain in autism, with largely inconsistent results.
Methods
The current study investigated the brain structural abnormal features of autistic individuals aged 6~30 years. We included 52 autism individuals and 50 age, gender, and IQ matched typically developing individuals (TD), who were divided into three groups: childhood (6-12 years old), adolescent (13-18 years old) and adulthood (19-30 years old). Whole brain volume and Voxel-Based Morphometry (VBM) analyses were employed on the sMRI data collected from our participants.
Results
We found no significant difference in the volume of whole brain, gray matter and white matter between autism and TD groups of the three age groups. For VBM analyses, the volumes of gray matter in right superior temporal gyrus and right inferior parietal lobule in children autism group were smaller than those in TD group; the volume of gray matter in left inferior parietal lobule in adolescent autism group was larger than that in TD group; the volume of gray matter in right middle occipital gyrus in adult autism group was larger than that in TD group, and the gray matter in left posterior cingulate gyrus was smaller than that in TD group.
Conclusions
Findings suggest autism individuals showed different atypical brain regions of gray matter volume in childhood, adolescent, and adulthood relative to their normal peers respectively, indiciating that it is essential to take developmental perspectives into consideration when exploring brain structural abnormalities in autism.
Rice Husk-Derived Mesoporous Silica Nanostructure for Supercapacitors Application: A Possible Approach for Recycling Bio-Waste into a Value-Added Product
Authors: Araichimani P. , Prabu K.M. , Kumar G. Suresh , Karunakaran Gopalu , Surendhiran S. , Shkir Mohd. 
Published: November 2021

Abstract
We synthesized mesoporous SiO2 nanomatrix using rice husks as a precursor through a facile thermal combustion process. XRD, FTIR, EDX, and TEM analyses were used to validate the produced mesoporous SiO2 nanomatrix. Electrochemical measurements were used to determine the specific capacitance of mesoporous SiO2 nanomatrix, and the results showed that the specific capacitances are 216, 204, 182, 163, 152, 142, 135, 133, 124.4, 124 F/g at current densities of 0.5, 1, 2, 4, 6, 8, 10, 12, 14, and 16 A/g. The benefit of impurities, as well as the large surface area and mesoporous structure of rice husk derived SiO2 nanostructures, allow Faradaic redox reactions at the electrode surface and the resulting supercapacitive behavior. This research might lead to a low-cost technique of producing supercapacitor electrodes using rice husk-derived SiO2 as a precursor.
Evaluating the effectiveness of a transdiagnostic universal prevention program for both internalizing and externalizing problems in children: Two feasibility studies
Authors: Kishida Kohei , Hida Noriko , Ishikawa Shin-ichi 
Published: November 2021

Abstract
Background
The present study examined the effectiveness of the Universal Unified Prevention Program for Diverse Disorders (Up2-D2) for internalizing and externalizing problems for children aged 9−11 years.
Methods
We used two feasibility studies. The Up2-D2 entailed 12 sessions delivered by teachers; each session was developed based on cognitive-behavioral and positive psychological interventions. In Studies 1 and 2, 58 elementary school children aged 9−11 and 73 elementary school children aged 10−11 attended the Up2-D2. The teachers in Study 1 received 1.5 hours of on-site teacher training for learning rationales for interventions, how to run the program, and received ongoing supervision by professionals with mental health expertise. In contrast, the teachers in Study 2 were given self-learning DVD materials in place of on-site training and ongoing supervision.
Results
Mixed models revealed that general difficulties, which is total score of both internalizing and externalizing problems, decreased in Study 1 but not in Study 2. Additional analyses for children with subclinical general difficulties revealed that general difficulties, internalizing problems, and externalizing problems decreased in Study 1, whereas in Study 2, general difficulties and internalizing problems decreased, except for externalizing problems.
Conclusions
These results suggest that on-site teacher training and ongoing supervision are imperative for improving general difficulties in children at a universal level. In addition, universal preventive interventions by classroom teachers without on-site training and continuous supervision might be efficacious for reducing general difficulties and internalizing problems for children with subclinical difficulties.
Comparison of Retention and Fracture Load of Endocrowns Made from Zirconia and Zirconium Lithium Silicate After Aging: An in-Vitro Study
Authors: Sahebi Majid , Ghodsi Safoura , Berahman Parsia , Amini Amirhesam , Zeighami Somayeh 
Published: November 2021

Abstract
Background: This study aimed to compare retention and fracture load in endocrowns made from zirconium lithium silicate and translucent zirconia.Methods: Fifty-six intact human maxillary molars after being mounted in acrylic resin, were scanned to acquire biogeneric copies. Specimens underwent standard endodontic treatment and were prepared for endocrown up to 2 mm above the cementoenamel junction. The specimens were randomly divided into two groups of 28 and endocrowns were designed using biogeneric copies and milled from high-translucent zirconia disks (Zr) and zirconium lithium silicate blocks (ZLS). After cementation with dual cure resin cement, all the specimens underwent thermomechanical aging and pull-out retention test and compressive test were conducted (14 specimens were used for each test in each group, n=14) and failure modes in both tests were evaluated.Results: Independent samples t-test showed significant difference between the retention of Zr (271.5 N ±114.31) and ZLS (654.67 N ±223.17) groups (p value = 0.012). Compressive test results were also significantly different between Zr (7395.07 N ±1947.42) and ZLS (1618.3 N ±585) (p = 0.002). Failure mode of retention test was primarily adhesive failure at the cement-restoration interface in Zr group and cement-tooth interface in ZLS group. Failure modes of fracture test for Zr group were 7 non-restorable fractures and one restorable fracture while 6 specimens resisted compressive loads up to 8500 N without fracture. ZLS group showed 7 restorable and 7 non-restorable failures.Conclusions: Zr endocrowns showed significantly lower retention and higher fracture strength. Both materials seem to be suitable for fabrication of endocrown in clinical setup.
SARS-CoV-2 as a Trigger in the Development of Tourette’s-Like Symptoms: A Case Report
Authors: Hazan Sabine , Jordan Sheldon 
Published: November 2021

Abstract
Background: Reports have been surfacing surrounding CNS-associated symptoms in individuals affected by coronavirus disease 19 (COVID-19). Tourette syndrome is a neuropsychiatric disorder with usual onset in childhood. Gut microbiota can affect central physiology and function via the microbiota-gut-brain axis. The authors of this case report describe Tourette’s-like symptoms in a patient resulting from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection disrupting gut microbiota. Case Presentation: This case involves a 16-year-old female that developed acute onset Tourette’s-like symptoms along with neuropsychiatric symptoms after exposure to and infection from SARS-CoV-2. The patient had negative nasopharyngeal (NP) real-time reverse transcription-PCR (RT-PCR) tests for SARS-CoV-2 on five occasions from August of 2020 through June of 2021. The patient’s symptoms continued to worsen over the next six months until next-generation sequencing (NGS) revealed SARS-CoV-2 in her stool. Her treatment was adjusted as NGS revealed SARS-CoV-2 in her stool. Repair of the gastrointestinal microbiota, treatment with nutraceutical and pharmaceutical agents, as well as alterations in her surroundings resulted in dramatic improvement in the microbiome and a significant reduction of symptoms.Discussion: The use of (RT-PCR) testing to determine the presence or absence of SARS-CoV-2 may be inadequate and inaccurate for individuals that have been exposed to the virus. In addition, the impact of SARS-CoV-2 infection of the GI tract may cause significant havoc in the gut microbiota. Additional testing, eradication of infectious agents, as well as restoration of the gut microbiome are needed to effectively manage and treat this condition. The patient’s symptoms worsened over the next six months until next-generation sequencing (NGS) revealed SARS-CoV-2 in her stool and her treatment was adjusted. Treatment with nutraceuticals and alterations in her surroundings was followed by a more normal microbiome and a dramatic reduction in symptoms.
Twenty-First Century Drought Analysis Across China using CMIP6 Under Climate Change
Authors: Zhang Gengxi , Gan Thian Yew , Su Xiaoling 
Published: November 2021

Abstract
Under global warming, according to results obtained from offline drought indices driven by projections of general circulation models (GCMs), future droughts in China will worsen but the results are not consistent. We analyzed changes in droughts covering the entire hydrologic cycle using outputs of GCMs of the 6th Coupled Model Intercomparison Project (CMIP6) for SSP2-4.5 and SSP5-8.5 climate scenarios, and compared the results with that of popular, offline drought indices (the self-calibrating Palmer Drought Severity Index (scPDSI), Standardized Precipitation Evapotranspiration Index (SPEI) and Standardized Precipitation Actual Evapotranspiration Index (SPAEI)). Among meteorological, agricultural, and hydrological drought indices tested under both SSP scenarios, the results obtained from SPAEI and scPDSI agree better with univariate drought indices than SPEI. scPDSI generally agrees well with agricultural droughts (Standardized Soil Moisture Index with the surface soil moisture content; SSIS). Future droughts estimated using soil moisture analysis are more widespread than that from precipitation and runoff analysis in humid regions of South China by the end of the 21st century. In arid northwestern China and Inner Mongolia, drought areas and severity based on scPDSI and SSIS forced with the SSP scenarios show obvious decreasing trends, in contrast to increasing trends projected in humid regions. Trends projected using SPEI contradict those projected by other drought indices in non-humid regions. Therefore, selecting appropriate drought indices are crucial in project representative future droughts and meaningful information needed to achieve effective regional drought mitigation strategies under climate warming impact.
Fast and Effective Catalytic Degradation of an Organic Dye by Eco-friendly Capped ZnS and Mn doped ZnS nanocrystals
Authors: Ouni Sabri , Mohamed Naim Bel Haj , Chaaben Noureddine , Bonilla-Petriciolet Adrian , Haouari Mohamed 
Published: November 2021

Abstract
Undoped and Mn-doped ZnS nanocrystals encapsulated with thioglycolic acid were synthetized and characterized with different techniques, and finally tested in the photodegradation of a methyl orange in aqueous solution under UV and sunlight irradiations. FTIR and X-ray diffraction results confirmed the functionalization of these nanocrystals surface by thioglycolic acid and the formation of crystalline structures of ZnS and Mn-doped ZnS with cubic and hexagonal phases. Calculated average size of ZnS nanocrystals was in the range of 2 - 3 nm. It was observed a blue shift of the absorbance threshold and the estimated bandgap energies were higher than that of Bulk ZnS thus confirming the quantum confinement effect of charge carriers. Photoluminescence spectra of ZnS nanocrystals exhibited emission in the range of 410- 490 nm and the appearance of an additional emission band around 580 nm (2.13eV) connected to the 4𝑇1→ 6𝐴1 transition of the Mn2+ions. Photodegradation of methylene orange with undoped and Mn-doped ZnS-TGA nanocrystals was investigated. Dye adsorption prior to photocatalysis using nanocrystals was studied via kinetic experiments and statistical physics models. The maximum dye adsorption capacity on doped ZnS-TGA was ~ 26.98 mg/g. The adsorption kinetic was found to follow the pseudo-second-order kinetic model.According to the statistical physics results, the calculated adsorption energy was 22.47-23.47 kJ/mol and it showed that the dye adsorption was associated to the hydrogen interaction where the removal process was feasible and multi-molecular. The photocatalytic activity of undoped ZnS nanoparticles under UV irradiation showed better efficiency than doped nanocrystals thus indicating that manganese doping generated a dropping of the photocatalytic degradation of the dye. Dye degradation efficiency of 81.37% using ZnS-TGA nanocrystals was achieved after 6 min, which indicated that ZnMnS-TGA nanocrystals may be considered as an alternative low cost and environmental friendly material for facing water pollution caused by organic compounds via photodegradation processes.
Effectiveness of Herb-partitioned Moxibustion on the Navel for Pregnancy Outcomes in Patients With Recurrent Implantation Failure Undergoing in Vitro Fertilization and Embryo Transfer: A Study Protocol for a Randomized Controlled Trial
Authors: Xia Qingchang , Gao Shuzhong , Song Jingyan , Du Dongqing , Li Chunjing , Zhou Yue , Zhang Xiaobin , Dong Zhibin , Ma Yuning , Ma Yuxia 
Published: November 2021

Abstract
BackgroundRecurrent implantation failure (RIF) in the majority of patients undergoing in vitro fertilization and embryo transfer (IVF-ET) is caused by various factors such as maternal age, embryo quality, endometrial receptivity (ER) and immunity. The incidence of RIF is usually between 5and 10%. Previous studies have shown that herb-partitioned moxibustion on the navel is one of the treatment methods of acupuncture with a positive effect on pregnancy. However, its application in the treatment of RIF has not been reported. Therefore, this study aimed to explore the effectiveness of herb-partitioned moxibustion on the navel in improving the outcome of frozen embryo transfer (FET) in patients with RIF. MethodsThis study conducted a randomized controlled trial (RCT). It is planned to recruit 210 patients undergoing RIF for FET from Affiliated Hospital of Shandong University of Traditional Chinese Medicine and randomly divide them into the treatment group and the control group in a ratio of 1:1. The patient of the treatment group will be treated with herb-partitioned moxibustion on the navel once a week for three consecutive menstrual cycles. During the fourth menstrual cycle, will be induced to prepare the endometrium before embryo transfer. No intervention will be used in the control group for 3 menstrual cycles. However, in the fourth menstrual cycle, an artificial cycle will be induced to prepare the endometrium before embryo transfer. The conception outcome will be recorded after a 3-months follow-up. Primary outcome will be assessed as the ongoing pregnancy rate compared with the control group. Secondary outcomes include the endometrial type, resistance index (RI), pulsatility index (PI) of the bilateral uterine artery, endometrial blood flow, serum estradiol (E2), progesterone (P), biochemical pregnancy rate, implantation rate and clinical pregnancy rate. DiscussionIf the results confirm that the herb-partitioned moxibustion on the navel can improve IVF-ET outcomes in patients with RIF, it will be recommended for application in clinical practice.Trial registration:Chinese clinical trial registry (ChiCTR). Trial registration number: ChiCTR2100043954. Registered on 8 July 2021.
Aerobic Exercise Inhibited P2X7 Purinergic Receptors to Improve Cardiac Remodeling in Mice with Type 2 Diabetes
Authors: Wang Ting , Li Jianmin , Li Hui , Zhong Xin , Wang Luya , Zhao Shuyu , Liu Xuesheng , Huang Zhouqing , Wang Yonghua 
Published: November 2021

Abstract
Background

Diabetic cardiomyopathy (DCM), the main complication of diabetes mellitus, presents as cardiac dysfunction by ventricular remodeling. In addition, the inhibition of P2X7 purinergic receptors (P2X7R) alleviates cardiac fibrosis and apoptosis in Type 1 diatebes. However, whether exercise training improves cardiac remodeling by regulating P2X7R remains unknown.
Methods

Db/db mice spontaneously induced with type 2 diabetes and high-fat diet (HFD) and mice with streptozotin (STZ)-induced type 2 diabetes mice were treated by 12-week treadmill training. Cardiac functions were observed by two-dimensional echocardiography. Hematoxylin-eosin staining, Sirius red staining and transmission electron microscopy were respectively used to detect cardiac morphology, fibrosis and mitochondria. In addidion, real-time polymerase chain reaction and Western Blot were used to detect mRNA and protein levels.
Results

Studying the hearts of db/db mice and STZ-induced mice, we found that collagen deposition and the number of disordered cells signiଁcantly increased compared with the control group. However, exercise markedly reversed these changes, and the same tendency was observed in the expression of MMP9, COL-I, and TGF-β, which indicated cardiac fibrotic and hypertrophic markers, including ANP and MyHC expression. In addition, the increased Caspase-3 level and the ratio of Bax/Bcl2 were reduced by exercise training, and similar results were observed in the TUNEL test. Notably, the expression of P2X7R was greatly upregulated in the hearts of db/db mice and HFD+STZ-induced DM mice and downregulated by aerobic exercise. Moreover, we indicated that P2X7R knock out signiଁcantly reduced the collagen deposition and disordered cells in the DM group. Furthermore, the apoptosis levels and TUNEL analysis were greatly inhibited by exercise or in the P2X7R−/− group in DM. We found significant differences between the P2X7R−/−+DM+EX group and DM+EX group in myocardial tissue apoptosis and fibrosis, in which the former is significantly milder. Moreover, compared with the P2X7R−/−+DM group, the P2X7R−/−+DM+EX group represented a lower level of cardiac fibrosis. The expression levels of TGF-β at the protein level and TGF-β and ANP at the genetic level were evidently decreased in the P2X7R−/−+DM+EX group.
Conclusion

Aerobic exercise reversed cardiac remodeling in diabetic mice at least partly through inhibiting P2X7R expression in cardiomyocytes.
Stochastic model predictive control for spacecraft rendezvous and docking via a distributionally robust optimization approach
Authors: Zuoxun Li , Zhang Kai 
Published: November 2021

A stochastic model predictive control (SMPC) algorithm is developed to solve the problem of three-dimensional spacecraft rendezvous and docking with unbounded disturbance. In particular, we only assume that the mean and variance information of the disturbance is available. In other words, the probability density function of the disturbance distribution is not fully known. Obstacle avoidance is considered during the rendezvous phase. Line-of-sight cone, attitude control bandwidth, and thrust direction constraints are considered during the docking phase. A distributionally robust optimization based algorithm is then proposed by reformulating the SMPC problem into a convex optimization problem. Numerical examples show that the proposed method improves the existing model predictive control based strategy and the robust model predictive control based strategy in the presence of disturbance.

doi:10.1017/S1446181121000031