bluuebunny/crossref_metadata_2025_split huggingface dataset:
A felnőtt korú cukorbetegek laboratóriumi vizsgálatainak elemzése hazánkban
Authors: Safadi Heléna , Lám Judit , Tislér András , Keresztes Katalin , Belicza Éva 
Published: December 2024

Bevezetés: A cukorbetegség a csökkenő incidenciája ellenére
továbbra is jelentős terhet ró a hazai ellátórendszerre, ugyanakkor a gondozási
gyakorlatról szisztematikus, nemzeti szintű felmérés ez idáig nem készült.
Célkitűzés: A hazai cukorbeteg-ellátás elemzése a javasolt
laboratóriumi vizsgálatok elvégzésének mértéke alapján, a rendelkezésre álló,
adminisztratív adatok tükrében. Módszer: Kutatásunkat a Nemzeti
Egészségbiztosítási Alapkezelőnél 2010–2021 között rendelkezésre álló
igénybevételi adatokból végeztük. Retrospektív kohorszvizsgálattal elemeztük a
cukorbetegek gondozása során, a szakmai irányelvek alapján kivitelezendő
laboratóriumi tesztek elvégzési arányát 4 kohorszban 4 éves megfigyelési
periódusban, valamint többváltozós logisztikus regressziós elemzéssel tártuk fel
a tesztek elvégzését befolyásoló tényezőket. Eredmények: A
vizsgálatba 128 115 beteget vontunk be. Kicsivel több mint 70%-uknál a 4 év
során legalább 3 különböző évben történt vércukor- és szérumkreatinin-vizsgálat,
míg HbA1c-, vizeletglükóz- és vizeletketonteszt a betegek 50–60%-a
esetén valósult meg. Az első antidiabetikum-kiváltást követő 4 évben kevesebb
mint 30%-ban történt LDL-koleszterin-, illetve vizeletalbumin-vizsgálat. A
pandémia hatása tetten érhető a vizsgálati arányok csökkenésében 2020–2021-ben.
A tesztek elvégzésének kisebb a valószínűsége férfiak, a fiatalabb korcsoportok,
valamint a csak metformint és/vagy szulfanilureát szedők esetén. Az eredmények
időben romló tendenciát mutatnak. Megbeszélés: Az eredmények
rámutatnak arra, hogy szükség van a cukorbeteg-ellátás feladat- és felelősségi
köreinek pontosabb meghatározására, a laboratóriumi vizsgálatok megvalósulását
segítő informatikai eszközök, emlékeztetőrendszerek és elérhető kapacitások
biztosítására, illetve az érintett betegpopuláció ismereteinek fejlesztésére.
Kutatásunk limitációja, hogy az adatokból a labortesztek eredménye nem, csak
elvégzésük ténye ismerhető meg, és a magánellátásban, illetve a ’point-of-care’
módon végzett tesztek nem jelennek meg benne. Következtetés: A
hazai érvényes szakmai irányelv fényében, csak a kapcsolódó laboratóriumi
teszteket vizsgálva megállapítható, hogy a cukorbeteg-ellátás működésének és a
mögöttes adatszolgáltatásnak vannak fejlesztendő területei. Az integrált ellátás
kialakítása, a feladatok és a hatáskörök egyértelmű meghatározása, a
’point-of-care’ vizsgálatok és a laboratóriumi vizsgálatok eredményeinek
beemelése az adatszolgáltatásba jelentősen hozzájárulhat a hazai
diabetesgondozás fejlődéséhez. Orv Hetil. 2024; 165(52): 2047–2060.
Legal Approaches in International Trade Compliance
Authors: Shakhnazarov B. A. 
Published: December 2024

Modern conditions imply the need for compliance procedures, the use of civil law instruments of due diligence, assurances and guarantees, etc., for the implementation of international trade relations, including various kinds of economic restrictions. Compliance with the requirements of international trade law has a significant impact on the development of industrial and trade relations complicated by a foreign element. The process of ensuring compliance with the requirements of international trade law refers to international trade compliance. When implementing international trade compliance procedures, it is important to ensure legal monitoring and control over export-import relations, in particular, international trade transactions, logistics, settlements, customs procedures, administrative and other mandatory requirements of the national legislation of exporting and importing countries, etc. In a dynamically changing environment, international trading companies must adapt to the new rules in order to ensure stability and legitimacy of cross-border trade operations, while respecting ethical and legal standards.The purpose of the paper is to study international trade compliance and determine its legal nature, propose the most effective legal compliance practices in the field of international trade and good practices for working with various regulatory requirements, develop proposals for optimizing legal educational programs in the field of international trade compliance, suggest new ideas for the use of automated solutions in the field of compliance and systematization of sanctions and anti-sanction restrictions.
Maternal factors affecting foetal outcome in rural area of district Amritsar, Punjab
Authors: Kaur Harpreet , Singh Rana Ranjit , Sharma Nishant 
Published: December 2024

Background: Birth weight not only indicates health of mother, nutrition and quality of life but also a pivotal factor in determining growth, survival and development of children. The key aspect influencing birth weight is maternal factors. Stress during pregnancy also affects a child's growth and development. So the present study was planned to assess the maternal factors affecting foetal outcomes. The level of stress among antenatal women was also determined in the study.
Methods: A prospective observational type of study was conducted from January to March, 2022. All the registered antenatal women were followed till outcome of pregnancy. Information was collected on predesigned and pretested proforma. Data analysis was done using SPSS version- 23.
Results: A total of 114 antenatal were registered in rural field practice area under Department of Community Medicine, SGRDIMSAR, Amritsar. There were 108 singleton live births and 6 miscarriages among registered antenatal women. Almost half (47.2%) of subjects got their pregnancy registered before 12 weeks. Recommended more than minimum 4 antenatal visits were conducted in almost half (49.1%) of women. Three fourth (75.9%) women in first trimester of pregnancy were suffering from moderate stress while 24.1% women were suffering from low stress.
Conclusions: In the present study maternal factors found to be significantly associated with birth weight of newborn were maternal age at first child, timing of 1st Antenatal visits, weight gain during pregnancy, number of Td (Tetanus diptheria) doses taken and consumption of IFA tablets. Perceived stress score (PSS) was also found to be significantly associated with birth weight of newborn.
Prevalence of low back pain and associated disability among women between 45-65 in Ernakulam district Kerala: a community-based cross-sectional study
Authors: Nazar Nija Musliyamveettil Abdul , C. Menon Jaideep , Kartha Niveditha 
Published: December 2024

Background: Low back pain is one of the most common health issues encountered worldwide. About 80% of the global population would have had an episode of LBP at some stage of life. Many of the musculoskeletal disorders develop in middle age and can be chronic lasting years, necessitating contact with health care providers.
Methods: A community-based cross-sectional study was conducted among 360 women in the age group of 45-65 years residing in Ernakulam (Kochi Corporation) for the past 6 months. Low back pain among women was assessed based on the Orebro musculoskeletal pain questionnaire. A modified Oswestry Low Back Pain Disability Questionnaire was used to measure the disability level. Participants were selected using cluster sampling (proportionate probability sampling). Data was analysed using IBM SPSS software version 20, Chicago USA.
Results: The mean age of study subjects was 55.49±7.01. Overall, the prevalence of low back pain was found to be 53.1%. Many women with low back pain experienced moderate disability (79.2%). The low back pain was influenced by socio-demographic variables that include age, diabetic status, presence of dyslipidaemia, presence of trauma (p<0.05). Disability was influenced by age, history of trauma, history of dyslipidemia, family type (joint) (p<0.05).
Conclusions: Prevalence of low back pain among women was comparatively higher than reported in other studies from India and was associated with a moderate degree of disability.
Clinical, radiological, and histopathological characteristics of patients with endobronchial lesions on fiberoptic bronchoscopy at a tertiary care hospital in central Karnataka region
Authors: Hatti Shubham S , Sangolli Basavaraj Sureshbabu , H N Jagadeesh , HM Virupaksha , SA Meghana 
Published: December 2024

Endobronchial lesions, originating from the bronchial wall, range from benign to malignant and include types such as squamous cell carcinoma, adenocarcinoma, and small cell carcinoma. They usually have similar clinical and radiological presentation making it difficult to distinguish them from one another. Fiberoptic bronchoscopy is one of the important tools for diagnosing and sampling of endobronchial lesions. Thus, in this study, we aim to identify Histopathological characteristics of lesions, besides noting their clinical and radiological profile. To evaluate the clinical, radiological, and histopathological profile of endobronchial characteristics identified through fiberoptic bronchoscopy. This was a retrospective study of Clinical, radiological and Histopathological characteristics of 29 patients, who had endobronchial lesions on fiberoptic bronchoscopy during the period of March 2020 - July 2023 at Respiratory medicine department, BMC&H, Chitradurga The majority (62.5%) of patients were between ages of 46 and 60, most (65.51) of them being males. Majority of the patients were smokers (55.17%). On bronchoscopy, Globular type of lesion (46.4%) was most common endobronchial lesion detected. A mass lesion (62.06%) was the most common radiological finding. Histo-pathologically, majority of lesions were malignant (96.55%) with Squamous cell carcinoma (37.5%) being the most common lesion. Most lesions were malignant, majority of which, presented radiologically as mass, encountered most often in males, as risk factors like smoking are common in males. Most common endobronchial lesion was an exophytic lesion and commonly involving the right main bronchus. As squamous cell carcinoma is central in location and frequently associated with smoking, it was the most common (42.85%) histopathological variant.
Toxicity of Phytochemical Monoterpenes against the Rice Weevil (Coleoptera: Curculionidae)1
Authors: Swapna Majjari , Jeyarani S. , Suganthi A. , Preetha G. , Uma D. , Sharmila Jeya Sundara D. 
Published: December 2024

Abstract
Postharvest insect pests pose a significant threat during product storage, diminishing both the quantity and quality of stored goods. Recently, plant-based pesticides have emerged as a promising alternative for managing storage pests. Plant essential oils are rich in biologically active monoterpenes, which have shown considerable potential as pest control agents due to their toxicity to insects. The purpose of the study was to assess the toxicity of six monoterpene compounds (citral, β-citronellol, eucalyptol, geraniol, β-myrcene, and thymol) against rice weevil, Sitophilus oryzae L. (Coleoptera: Curculionidae). Among the tested monoterpenes, thymol and geraniol exhibited the highest contact toxicity, with 50% lethal concentration (LC50) values of 63.16 and 70.77 μl/cm2 against S. oryzae, respectively, at 72 h after treatment, followed by β-citronellol and citral. The fumigant activity of the compounds tested at concentrations ranging between 20.0 and 100.0 μl/ml of air was highest with β-citronellol (LC50 of 22.12 μl/ml of air), followed by citral (LC50 of 32.23 μl/ml of air) at 72 h after exposure. β-Myrcene and geraniol also exhibited fumigant toxicity but at levels lower than β-citronellol or citral. Among the six monoterpenes, geraniol showed highest repellent activity of 90.00% ±1.44%, followed by β-citronellol (75.00% ± 2.88%) and citral (71.75% ± 1.25%) at 4 h of exposure at 7.5 μl/cm2. In sum, the six tested monoterpenes exhibited moderate to high toxicity against S. oryzae, suggesting that they have the potential to be developed and used as effective alternatives for managing S. oryzae in stored products.
Reproducibility of the Time of Intraocular Pressure Peaks During Water-drinking Test in Patients Treated for Open-angle Glaucoma
Authors: Susanna Carolina TN , De Moraes C. Gustavo , Alhadeff Paula , Susanna Bianca , Susanna Fernanda , Germano Renato Antunes Schiave , Susanna Remo 
Published: December 2024

Purpose: To evaluate the reproducibility and between-eyes symmetry of time of the intraocular pressure (IOP) elicited with the water drinking test (WDT) in treated glaucomatous patients.Methods: Prospective cohort study that included ninety-nine patients, 198 eyes of treated primary open-angle glaucoma patients. All patients underwent the WDT performed in two consecutive visits without any change in the therapeutic regimen. The interval between tests was 4 to 6 months. The test was performed at the same time of the day (4.00PM +/- one hour). The reproducibility of time of the IOP peak and the relationship between peak times between fellow eyes during the two consecutive WDT sessions were assessed.Results: 59.6% and 71% of IOP peaks occurred at the same time during the two WDT sessions in right and left eyes, respectively. In the first and second WDT sessions, the agreement in IOP peak times between eyes was 60% and 63%, respectively. Conclusion: There was modest reproducibility in the time of IOP peaks between two consecutive WDT sessions, as well as moderate agreement in the time of peaks between fellow eyes. In light of these findings, clinicians should avoid performing simplified versions of the WDT to evaluate IOP peaks.
Detection of urine circulating tumor DNA using droplet digital PCR for predicting hepatocellular carcinoma recurrence
Authors: Zhang Xin , Huang Pei-Xin , Ma Bin , Guo De-Zhen , Huang Ao , Liu Wei-Ren , Ding Zhen-Bin , Shi Ying-Hong , Fan Jia , Zhou Jian , Huang Jun-Feng , Fu Xiu-Tao 
Published: December 2024

Aim: This study aims to evaluate the feasibility of examining circulating tumor DNA (ctDNA) in urine samples from hepatocellular carcinoma (HCC) patients by droplet digital PCR (ddPCR) and to assess its value in predicting HCC recurrence after surgery.
Methods: HCC cases who accepted surgical resection were included. Perioperative urine, tissue and peripheral blood specimens were collected. Four hotspot mutants [TP53 -rs28934571 (c.747G>T), TRET -rs1242535815 (c.1-124C>T), CTNNB1 -rs121913412 (c.121A>G), and CTNNB1 -rs121913407 (c.133T>C)] were chosen for ctDNA analysis, and mutant allele frequency (MAF) was worked out. Sanger sequencing was performed on matched tumor tissues and peripheral blood mononuclear cells (PBMCs). The patients’ clinicopathologic characteristics were retrospectively analyzed. The predictive abilities of urine ctDNA for postoperative recurrence were evaluated using the Kaplan-Meier method.
Results: Forty-six patients were enrolled, and 18 patients (39.1%, 18/46) exhibited detectable circulating mutants, with the MAF in the range of 0.07% to 0.91%. The consistency test indicated moderate to substantial concordance between urine and paired tumor tissue mutations. The mutation level dropped dramatically or disappeared after surgery. Positive urine ctDNA before surgery was closely related to greater tumor size and recurrence. Kaplan-Meier curves revealed significantly shorter disease-free survival (DFS) for ctDNA-positive patients. Multivariate analysis identified detectable urine ctDNA as an independent risk factor for tumor recurrence. More than that, receiver operating characteristic (ROC) curves demonstrated that urine ctDNA had the largest area under the curve (AUC) for predicting HCC recurrence.
Conclusion: Detecting ctDNA in urine using ddPCR is feasible and holds significant potential for predicting and monitoring HCC recurrence.
Дослідження шляхів створення імпульсних генераторів терагерцового діапазону на кремнієвих IMPATT-діодах
Authors: Бичок Андрій Володимирович , Зоренко Олександр Вольтович , Соболєв Дмитро Вікторович , Волков Євгеній Георгійович 
Published: December 2024

Стаття присвячена розгляду питань, що стосуються пошуку шляхів створення імпульсних джерел потужності терагерцового діапазону. Представлені результати математичного моделювання енергетичних та імпедансних характеристик кремнієвих IMPATT-діодів у діапазоні частот 200-300 ГГц та елементів узгодження імпедансу напівпровідникової структури з імпедансом хвилеводної лінії передачі. На основі результатів розрахунків проведено оптимізацію діодних структур з метою отримання максимальних значень НВЧ-потужності в імпульсному режимі. Наведено параметри експериментальних зразків кремнієвих двопрогонових IMPATT-діодів, виготовлених з урахуванням даних математичного моделювання. Отримано імпульсну НВЧ потужність 0,416 Вт на частоті 233 ГГц при тривалості НВЧ імпульсу 35 нс.
Enhancing Students' Ability to Write Personal Experiences in Sundanese Language through a Contextual Learning Approach
Authors: Fitriani Fanny , Boeriswati Endry , Ekowati Sri Harini 
Published: December 2024

Learning to write by using Sundanese language in Junior High School get to attention from Sundanese teacher. When learning to write personal experience, students always feel difficult especially in using language. The most of result, students writing problems are spelling, punctuation and diction of Sundanese language. This research to increase students’ skill in writing personal experience through contextual approach. The method used in this research was classroom action research by combining qualitative and quantitative data and following Kemmis & Taggart’s research model approach, which consists of 4 stages in each cycle, i.e., planning, action/implementation, observation, and reflection. Qualitative data was analyzed by describing the action research process and the quality of students' ability to write short stories through the contextual approach, while quantitative data was analyzed using percentages. This study showed an increase in the ability to write personal experiences through a contextual approach starting from pre-action, cycle 1, cycle 2, and cycle 3. Cycle I, there was an increase in the average writing score, which became writing skills, which became 73.4, the number of learners who reached the minimum cut-off score was 12 learners or 48% of the total number of learners. In Cycle II, the average score of the learners' writing skills increased again to 78.76, there were 19 (76%) learners who scored ≥75, and in Cycle III, the average score of the learners' writing skills increased again to 84.64, all the learners met the KKM, where the lowest score was 77 and the highest score was 97. Finally, based on the research findings, the application of a contextual approach in writing personal experience with the Sundanese language makes the Sundanese language learning process more dynamic and fun.
Cintadiri.Id : Pencegahan dan Penanganan Self-Harm Berbasis Sistem Informasi
Authors: Faradiba Andi Tenri , Syihab Aisyah , Arsad Bambang Riono , Sumarno Rahayu , Prameswari Larashaty Putri , Aridin Icha Puspita , Bintang Arthan Laki , Wiraputra Ayala Muhammad 
Published: December 2024

Non-suicidal self-injury (NSSI) or self-harm is on the rise among Indonesian adolescents. As digital natives, they often turn to the internet for information, including mental health support. To address this issue, a team from the Faculty of Psychology and Informatics Engineering at Universitas Pancasila developed cintadiri.id, an information system designed to prevent and handle self-harm. The website offers a range of features, including psychoeducational articles, relaxation videos, a journaling tool, and consultations with psychologists. To evaluate the website's effectiveness, a survey was conducted among 30 participants aged 17-21. There are five questions given, such as "how attractive the design is", "how useful the website is", "how helpful". The results obtained an average value of 3.73 (scale 1-5) for all answers. This shows that the cintadiri.id website is feasible as a website that has the potential to prevent and handle self-harm. The development of this website and research on the use of websites as a tool to help handle self-are needed.

Abstrak
Perilaku melukai diri sendiri tanpa intensi untuk bunuh diri, yang dikenal dengan istilah self-harm semakin marak dilakukan di Indonesia, khususnya oleh remaja. Remaja saat ini merupakan digital native yang banyak mencari informasi di internet, termasuk mencari bantuan psikologis terkait masalah yang sedang mereka hadapi. Maka dibutuhkan suatu sistem informasi untuk membantu pencegahan dan penanganan self-harm yang dilakukan oleh remaja. Kebutuhan akan hal tersebut dapat dipenuhi dengan pembuatan website yang dilakukan oleh tim dari Fakultas Psikologi dan Teknik Informatika Universitas Pancasila. Website untuk mencegah dan menangani self-harm yang dibuat dinamakan cintadiri.id yang merupakan bentuk kegiatan pengabdian kepada masyarakat dengan jenis psikoedukasi secara online dan bersifat tetap. Pada website ini terdapat berbagai fitur, yaitu artikel psikoedukasi untuk mencegah self-harm, video relaksasi pernapasan untuk membantu pengguna menstabilkan emosi ketika merasakan emosi negatif berlebihan akibat peristiwa yang dihadapi, fitur journaling dan fitur bantuan layanan konsultasi psikologis dari Universitas Pancasila. Untuk mengetahui apakah website cintadiri.id memiliki kelayakan sebagai sistem informasi untuk mencegah dan menangani self-harm, maka dilakukan pengambilan data kepada 30 orang partisipan dengan rentang usia 17-21 tahun. Ada lima pertanyaan yang diberikan, seperti “seberapa menarik desainnya”, “seberapa berguna webnya”, “seberapa membantu”. Hasil diperoleh nilai rata-rata 3,73 (skala 1-5) untuk semua jawaban. Hal ini menunjukkan bahwa web cintadiri.id layak sebagai web yang berpotensi dapat mencegah dan menangani self-harm. Adapun pengembangan terhadap website ini masih terus dilakukan dan penelitian penggunaan website sebagai alat membantu penanganan self-harm masih perlu dilakukan.