bluuebunny/crossref_metadata_2025_split huggingface dataset:
Artificial neural network classification of asteroids in the M1:2 mean-motion resonance with Mars
Authors: Carruba V , Aljbaae S , Domingos R C , Barletta W 
Published: March 2021

ABSTRACT
Artificial neural networks (ANNs) have been successfully used in the last years to identify patterns in astronomical images. The use of ANN in the field of asteroid dynamics has been, however, so far somewhat limited. In this work, we used for the first time ANN for the purpose of automatically identifying the behaviour of asteroid orbits affected by the M1:2 mean-motion resonance with Mars. Our model was able to perform well above 85 per cent levels for identifying images of asteroid resonant arguments in term of standard metrics like accuracy, precision, and recall, allowing to identify the orbital type of all numbered asteroids in the region. Using supervised machine learning methods, optimized through the use of genetic algorithms, we also predicted the orbital status of all multi-opposition asteroids in the area. We confirm that the M1:2 resonance mainly affects the orbits of the Massalia, Nysa, and Vesta asteroid families.
MRI-active inner regions of protoplanetary discs. I. A detailed model of disc structure
Authors: Jankovic Marija R , Owen James E , Mohanty Subhanjoy , Tan Jonathan C 
Published: March 2021

ABSTRACT
Short-period super-Earth-sized planets are common. Explaining how they form near their present orbits requires understanding the structure of the inner regions of protoplanetary discs. Previous studies have argued that the hot inner protoplanetary disc is unstable to the magnetorotational instability (MRI) due to thermal ionization of potassium, and that a local gas pressure maximum forms at the outer edge of this MRI-active zone. Here we present a steady-state model for inner discs accreting viscously, primarily due to the MRI. The structure and MRI-viscosity of the inner disc are fully coupled in our model; moreover, we account for many processes omitted in previous such models, including disc heating by both accretion and stellar irradiation, vertical energy transport, realistic dust opacities, dust effects on disc ionization, and non-thermal sources of ionization. For a disc around a solar-mass star with a standard gas accretion rate ($\dot{M}\, \sim \, 10^{-8}$ M⊙ yr−1) and small dust grains, we find that the inner disc is optically thick, and the accretion heat is primarily released near the mid-plane. As a result, both the disc mid-plane temperature and the location of the pressure maximum are only marginally affected by stellar irradiation, and the inner disc is also convectively unstable. As previously suggested, the inner disc is primarily ionized through thermionic and potassium ion emission from dust grains, which, at high temperatures, counteract adsorption of free charges on to grains. Our results show that the location of the pressure maximum is determined by the threshold temperature above which thermionic and ion emission become efficient.
HD 143006: circumbinary planet or misaligned disc?
Authors: Ballabio G , Nealon R , Alexander R D , Cuello N , Pinte C , Price D J 
Published: March 2021

ABSTRACT
Misalignments within protoplanetary discs are now commonly observed, and features such as shadows in scattered light images indicate departure from a co-planar geometry. VLT/SPHERE (Very Large Telescope/Spectro-Polarimetric High-​contrast Exoplanet REsearch) observations of the disc around HD 143006 show a large-scale asymmetry and two narrow dark lanes that are indicative of shadowing. ALMA (Atacama Large Millimeter/submillimeter Array) observations also reveal the presence of rings and gaps in the disc, along with a bright arc at large radii. We present new hydrodynamic simulations of HD 143006, and show that a configuration with both a strongly inclined binary and an outer planetary companion is the most plausible to explain the observed morphological features. We compute synthetic observations from our simulations, and successfully reproduce both the narrow shadows and the brightness asymmetry seen in infrared scattered light. Additionally, we reproduce the large dust observed in the mm continuum, due to a 10 Jupiter-mass planet detected in the CO kinematics. Our simulations also show the formation of a circumplanetary disc, which is misaligned with respect to the outer disc. The narrow shadows cast by the inner disc and the planet-induced ‘kink’ in the disc kinematics are both expected to move on a time-scale of ∼5–10 yr, presenting a potentially observable test of our model. If confirmed, HD 143006 would be the first known example of a circumbinary planet on a strongly misaligned orbit.
The size and pervasiveness of Ly α–UV spatial offsets in star-forming galaxies at z ∼ 6
Authors: Lemaux B C , Fuller S , Bradač M , Pentericci L , Hoag A , Strait V , Treu T , Alvarez C , Bolan P , Gandhi P J , Huang K-H , Jones T , Mason C , Pelliccia D , Ribeiro B , Ryan R E , Schmidt K B , Vanzella E , Khusanova Y , Le Fèvre O , Guaita L , Hathi N P , Koekemoer A , Pforr J 
Published: March 2021

ABSTRACT
We study the projected spatial offset between the ultraviolet continuum and Ly α emission for 65 lensed and unlensed galaxies in the Epoch of Reionization (5 ≤ z ≤ 7), the first such study at these redshifts, in order to understand the potential for these offsets to confuse estimates of the Ly α properties of galaxies observed in slit spectroscopy. While we find that ∼40 per cent of galaxies in our sample show significant projected spatial offsets ($|\Delta _{\rm {Ly}\alpha -\rm {UV}}|$), we find a relatively modest average projected offset of $|\widetilde{\Delta }_{\rm {Ly}\alpha -\rm {UV}}|$ = 0.61 ± 0.08 proper kpc for the entire sample. A small fraction of our sample, ∼10 per cent, exhibit offsets in excess of 2 proper kpc, with offsets seen up to ∼4 proper kpc, sizes that are considerably larger than the effective radii of typical galaxies at these redshifts. An internal comparison and a comparison to studies at lower redshift yielded no significant evidence of evolution of $|\Delta _{\rm {Ly}\alpha -\rm {UV}}|$ with redshift. In our sample, ultraviolet (UV)-bright galaxies ($\widetilde{L_{\mathrm{ UV}}}/L^{\ast }_{\mathrm{ UV}}=0.67$) showed offsets a factor of three greater than their fainter counterparts ($\widetilde{L_{\mathrm{ UV}}}/L^{\ast }_{\mathrm{ UV}}=0.10$), 0.89 ± 0.18 versus 0.27 ± 0.05 proper kpc, respectively. The presence of companion galaxies and early stage merging activity appeared to be unlikely causes of these offsets. Rather, these offsets appear consistent with a scenario in which internal anisotropic processes resulting from stellar feedback, which is stronger in UV-brighter galaxies, facilitate Ly α fluorescence and/or backscattering from nearby or outflowing gas. The reduction in the Ly α flux due to offsets was quantified. It was found that the differential loss of Ly α photons for galaxies with average offsets is not, if corrected for, a limiting factor for all but the narrowest slit widths (&lt;0.4 arcsec). However, for the largest offsets, if they are mostly perpendicular to the slit major axis, slit losses were found to be extremely severe in cases where slit widths of ≤1 arcsec were employed, such as those planned for James Webb Space Telescope/NIRSpec observations.
Asymmetry in histone rotation in forced unwrapping and force quench rewrapping in a nucleosome
Authors: Reddy Govardhan , Thirumalai D 
Published: March 2021

Abstract
Single molecule pulling experiments have shown that DNA in the nucleosomes unwraps in two stages from the histone protein core (HPC). The first stage, attributed to the rupture of the outer DNA turn, occurs between 3 and 5 pNs, and is reversible. The inner DNA turn ruptures irreversibly at forces between 9 and 15 pNs (or higher) in the second stage. Molecular simulations using the Self-Organized Polymer model capture the experimental findings. The unwrapping of the outer DNA turn is independent of the pulling direction. The rupture of the DNA inner turn depends on the pulling direction and involves overcoming substantial energetic (most likely electrostatic in origin) and kinetic barriers. They arise because the mechanical force has to generate sufficient torque to rotate the HPC by 180°. On the other hand, during the rewrapping process, HPC rotation is stochastic, with force playing no role. The assembly of the outer DNA wrap upon force quench nearly coincides with the unwrapping process, confirming the reversibility of the outer turn rupture. The asymmetry in HPC rotation during unwrapping and rewrapping explains the observed hysteresis in the stretch-release cycles in experiments. We propose experiments to test the prediction that HPC rotation produces kinetic barriers in the unwrapping process.
Conscious perception and perceptual echoes: a binocular rivalry study
Authors: Luo Canhuang , VanRullen Rufin , Alamia Andrea 
Published: March 2021

Abstract
Alpha rhythms (∼10Hz) in the human brain are classically associated with idling activities, being predominantly observed during quiet restfulness with closed eyes. However, recent studies demonstrated that alpha (∼10Hz) rhythms can directly relate to visual stimulation, resulting in oscillations, which can last for as long as one second. This alpha reverberation, dubbed perceptual echoes (PE), suggests that the visual system actively samples and processes visual information within the alpha-band frequency. Although PE have been linked to various visual functions, their underlying mechanisms and functional role are not completely understood. In this study, we investigated the relationship between conscious perception and the generation and the amplitude of PE. Specifically, we displayed two coloured Gabor patches with different orientations on opposite sides of the screen, and using a set of dichoptic mirrors, we induced a binocular rivalry between the two stimuli. We asked participants to continuously report which one of two Gabor patches they consciously perceived, while recording their EEG signals. Importantly, the luminance of each patch fluctuated randomly over time, generating random sequences from which we estimated two impulse-response functions (IRFs) reflecting the PE generated by the perceived (dominant) and non-perceived (suppressed) stimulus, respectively. We found that the alpha power of the PE generated by the consciously perceived stimulus was comparable with that of the PE generated during monocular vision (control condition) and higher than the PE induced by the suppressed stimulus. Moreover, confirming previous findings, we found that all PEs propagated as a travelling wave from posterior to frontal brain regions, irrespective of conscious perception. All in all our results demonstrate a correlation between conscious perception and PE, suggesting that the synchronization of neural activity plays an important role in visual sampling and conscious perception.
The Global Epidemiology of RSV in Community and Hospitalized Care: Findings From 15 Countries
Authors: Staadegaard Lisa , Caini Saverio , Wangchuk Sonam , Thapa Binay , de Almeida Walquiria Aparecida Ferreira , de Carvalho Felipe Cotrim , Njouom Richard , Fasce Rodrigo A , Bustos Patricia , Kyncl Jan , Novakova Ludmila , Caicedo Alfredo Bruno , de Mora Coloma Domenica Joseth , Meijer Adam , Hooiveld Mariëtte , Huang Sue , Wood Tim , Guiomar Raquel , Rodrigues Ana Paula , Danilenko Daria , Stolyarov Kirill , Lee Vernon Jian Ming , Ang Li Wei , Cohen Cheryl , Moyes Jocelyn , Larrauri Amparo , Delgado-Sanz Concepción , Le Mai Quynh , Hoang Phuong Vu Mai , Demont Clarisse , Bangert Mathieu , van Summeren Jojanneke , Dückers Michel , Paget John 
Published: March 2021

Abstract

Background
Respiratory syncytial virus (RSV) is one of the leading causes of acute respiratory tract infections. To optimize control strategies, a better understanding of the global epidemiology of RSV is critical. To this end, we initiated the Global Epidemiology of RSV in Hospitalized and Community care study (GERi).

Methods
Focal points from 44 countries were approached to join GERi and share detailed RSV surveillance data. Countries completed a questionnaire on the characteristics of their surveillance system.

Results
Fifteen countries provided granular surveillance data and information on their surveillance system. A median (interquartile range) of 1641 (552–2415) RSV cases per season were reported from 2000 and 2020. The majority (55%) of RSV cases occurred in the &lt;1-year-olds, with 8% of cases reported in those aged ≥65 years. Hospitalized cases were younger than those in community care. We found no age difference between RSV subtypes and no clear pattern of dominant subtypes.

Conclusions
The high number of cases in the &lt;1-year-olds indicates a need to focus prevention efforts in this group. The minimal differences between RSV subtypes and their co-circulation implies that prevention needs to target both subtypes. Importantly, there appears to be a lack of RSV surveillance data in the elderly.
Ultraconserved Elements Improve the Resolution of Difficult Nodes within the Rapid Radiation of Neotropical Sigmodontine Rodents (Cricetidae: Sigmodontinae)
Authors: Parada Andrés , Hanson John , D’Eiía Guillermo 
Published: March 2021

AbstractSigmodontine rodents (Cricetidae, Sigmodontinae) represent the second largest muroid subfamily and the most species-rich group of New World mammals, encompassing above 410 living species and ca. 87 genera. Even with advances on the clarification of sigmodontine phylogenetic relationships that have been made recently, the phylogenetic relationships among the 12 main groups of genera (i.e., tribes) remain poorly resolved, in particular among those forming the large clade Oryzomyalia. This pattern has been interpreted as consequence of a rapid radiation upon the group entrance into South America. Here, we attempted to resolve phylogenetic relationships within Sigmodontinae using target capture and high-throughput sequencing of ultraconserved elements (UCEs). We enriched and sequenced UCEs for 56 individuals and collected data from four already available genomes. Analyses of distinct data sets, based on the capture of 4634 loci, resulted in a highly resolved phylogeny consistent across different methods. Coalescent species-tree-based approaches, concatenated matrices, and Bayesian analyses recovered similar topologies that were congruent at the resolution of difficult nodes. We recovered good support for the intertribal relationships within Oryzomyalia; for instance, the tribe Oryzomyini appears as the sister taxa of the remaining oryzomyalid tribes. The estimates of divergence times agree with the results of previous studies. We inferred the crown age of the sigmodontine rodents at the end of the Middle Miocene, while the main lineages of Oryzomyalia appear to have radiated in a short interval during the Late Miocene. Thus, the collection of a genomic-scale data set with a wide taxonomic sampling provided resolution for the first time of the relationships among the main lineages of Sigmodontinae. We expect the phylogeny presented here will become the backbone for future systematic and evolutionary studies of the group.[Coalescent; Muroidea; Oryzomyalia; phylogenomics; polytomy; Rodentia; Sigmodontalia; species tree; UCEs.]
The discovery, distribution, and diversity of DNA viruses associated withDrosophila melanogasterin Europe
Authors: Wallace Megan A , Coffman Kelsey A , Gilbert Clément , Ravindran Sanjana , Albery Gregory F , Abbott Jessica , Argyridou Eliza , Bellosta Paola , Betancourt Andrea J , Colinet Hervé , Eric Katarina , Glaser-Schmitt Amanda , Grath Sonja , Jelic Mihailo , Kankare Maaria , Kozeretska Iryna , Loeschcke Volker , Montchamp-Moreau Catherine , Ometto Lino , Onder Banu Sebnem , Orengo Dorcas J , Parsch John , Pascual Marta , Patenkovic Aleksandra , Puerma Eva , Ritchie Michael G , Rota-Stabelli Omar , Schou Mads Fristrup , Serga Svitlana V , Stamenkovic-Radak Marina , Tanaskovic Marija , Veselinovic Marija Savic , Vieira Jorge , Vieira Cristina P , Kapun Martin , Flatt Thomas , González Josefa , Staubach Fabian , Obbard Darren J 
Published: March 2021

AbstractDrosophila melanogaster is an important model for antiviral immunity in arthropods, but very few DNA viruses have been described from the family Drosophilidae. This deficiency limits our opportunity to use natural host-pathogen combinations in experimental studies, and may bias our understanding of the Drosophila virome. Here, we report fourteen DNA viruses detected in a metagenomic analysis of 6668 pool-sequenced Drosophila, sampled from forty-seven European locations between 2014 and 2016. These include three new nudiviruses, a new and divergent entomopoxvirus, a virus related to Leptopilina boulardi filamentous virus, and a virus related to Musca domestica salivary gland hypertrophy virus. We also find an endogenous genomic copy of galbut virus, a double-stranded RNA partitivirus, segregating at very low frequency. Remarkably, we find that Drosophila Vesanto virus, a small DNA virus previously described as a bidnavirus, may be composed of up to twelve segments and thus represent a new lineage of segmented DNA viruses. Two of the DNA viruses, Drosophila Kallithea nudivirus and Drosophila Vesanto virus are relatively common, found in 2 per cent or more of wild flies. The others are rare, with many likely to be represented by a single infected fly. We find that virus prevalence in Europe reflects the prevalence seen in publicly available datasets, with Drosophila Kallithea nudivirus and Drosophila Vesanto virus the only ones commonly detectable in public data from wild-caught flies and large population cages, and the other viruses being rare or absent. These analyses suggest that DNA viruses are at lower prevalence than RNA viruses in D.melanogaster, and may be less likely to persist in laboratory cultures. Our findings go some way to redressing an earlier bias toward RNA virus studies in Drosophila, and lay the foundation needed to harness the power of Drosophila as a model system for the study of DNA viruses.
Examining Use of Dual Point Temperature Display in Servo-Control With Early Preterm Infants
Authors: Dail Robin B. , Tavakoli Abbas S. , Moseley Sherry L. , Bergstedt Victoria B. , Kuehn Devon , Chang Weili 
Published: March 2021

Background:
Previously, we recorded periods of time with foot higher than abdominal temperatures in association with infection in preterm infants. Monitoring dual temperatures may be an important tool to assess infant instability. Currently, incubators cannot measure and display dual temperatures in servo-control mode.

Purpose:
To examine the usability of GE Healthcare's Giraffe OmniBed with research software to measure, display, and record dual temperatures, and their differences while in servo-control. In addition, nurses' perceptions of the use and display of dual temperatures and differences were evaluated.

Methods:
A multiple-case, mixed-methods design. Abdominal and foot temperatures were measured, displayed, and stored for 28 days for 14 preterm infants. Nurses were surveyed for satisfaction and preferences with the dual temperature display. Nurses noted abnormal temperature differences and infant condition in bedside journals.

Results:
Study infants were 26 to 31 weeks of gestational age and 670 to 1410 g. Abdominal, foot, and the abdominal-foot temperature difference was measured, recorded, and downloaded successfully in all infants over all days. Nurses liked using dual temperature display with the abdominal-foot temperature difference. Surveys indicated preferences for larger displays and alarms for abnormal values. Thermal instability, stimulation, and thermistor detachment were associated with abnormal thermal gradients. Two exemplar cases are presented.

Implications for Practice:
Monitoring dual temperatures adds information to the clinical assessment.

Implications for Research:
Studies are needed to examine relationships between abnormal thermal gradients and infections, infant stability, and nursing care along with the underlying physiologic mechanisms. Studies are needed for wireless dual temperature monitoring.
Decreasing Complete Blood Count Clotting Rates
Authors: Giddens Emily 
Published: March 2021

Background:
In premature and critically ill infants, a complete blood count (CBC) is commonly collected via the heel-stick method, which is preferred because of the ongoing requirements to preserve intravenous sites. However, because of sample clotting, these specimens are often rejected, leading to unnecessary repeat heel sticks, painful stimuli, and increased costs.

Purpose:
The purpose of this quality improvement project was to decrease the rate of clotted CBC samples obtained from neonates admitted in the neonatal intensive care unit.

Methods:
The RE-AIM translation model, which stands for Reach, Effectiveness, Adoption, Implementation, and Maintenance, was adopted to decrease the rate of clotted CBC samples through staff education, randomized audits of the staff's heel-stick technique, and the development and implementation of a standardized capillary blood sampling protocol. The primary outcome measure was the rate of clotted CBC samples, which was defined as the proportion of clotted CBC samples.

Results:
CBC clotted sample rates decreased by 27%, resulting in a cost saving of $1136, and overall CBC rejection rates decreased by 23%.

Implications for Practice:
All hospital units should provide staff with an evidence-based resource, recurrent education, and evaluation of skills to avoid unnecessary repeat heel sticks and prevent increased pain sensitivity, social hypervigilance, and avoidance behavior in early infancy.

Implications for Research:
Future efforts should focus on the long-term benefits of routine education and its effects on clotted sample rates and whether samples drawn by laboratory phlebotomy staff versus registered nurses/patient care technicians result in disproportionate rejection rates.
Risk Factors Associated With Long-term Feeding Problems in Preterm Infants
Authors: Fucile Sandra , Samdup Dawa , MacFarlane Vanessa , Sinclair McKenzie A. 
Published: March 2021

Background:
Infants who are born preterm are at a high risk of encountering feeding problems.

Purpose:
The aim of this scoping review is to identify risk factors associated with feeding problems that persist beyond infancy in children (aged 1-6 years) who were born preterm (<37 weeks' gestation).

Methods:
To perform this scoping review, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses framework was applied. To be included in this study, articles had to be published in peer-reviewed journals, had an empirical study design, examined feeding problems relating to the child's feeding ability or refusal to eat certain texture of foods, and assessed risk factors (age, weight, and medical conditions) associated with long-term feeding problems in children who were born preterm.

Results:
After abstract and full-text screening, a total of 9 articles meeting the inclusion criteria were included in this study. Findings from this study identified that gestational age and birth weight are significant risk factors and that sex, duration of mechanical ventilation, and length of tube feedings are potential risk factors.

Implications for Practice:
This study confirms that younger and smaller infants are at a high risk of encountering oral feeding difficulties and early interventions services should be focused on these preterm infants.

Implications for Research:
Evaluation of timing and intensity (dose) of early interventions strategies should be investigated to provide more targeted and effective interventions for younger and smaller preterm infants.