bluuebunny/crossref_metadata_2025_split huggingface dataset:
Attachement, personnalité et violence conjugale psychologique chez des femmes en psychothérapie
Authors: Cloutier Gabrielle , Nolin Marie-Chloé , Côté Laurence , Sabourin Stéphane , Bellemare Vincent 
Published: January 2021

Puisque la violence conjugale psychologique (VCP) perpétrée par les femmes représente une problématique ayant une importante prévalence, la présente étude vise à expliquer le lien entre les deux dimensions de l’attachement et la VCP via les traits de la personnalité. L’échantillon est composé de femmes consultant en thérapie individuelle ou de couple au Service de consultation de l’École de psychologie de l’Université Laval qui ont rempli des questionnaires mesurant l’attachement, les traits de la personnalité et la VCP. L’analyse effectuée afin de tester les hypothèses est l’analyse acheminatoire. L’agréabilité s’est avérée être un médiateur significatif du lien entre l’anxiété d’abandon et la VCP et du lien entre l’évitement de l’intimité et la VCP, alors que l’extraversion est un médiateur du lien entre l’évitement de l’intimité et la VCP. Le modèle comprenant les deux dimensions de l’attachement et les cinq traits de la personnalité explique 12 % des variations de la VCP.
Digital Humanities Approaches to Literary Translation
Authors: Sun Yifeng , Li Dechao 
Published: January 2021

Abstract
Digital humanities (DH), which first started as the compilation, digitization, and visualization of ample amounts of archival works of particular writers and artists (such as the projects of Rossetti Archive and William Blake Archive) at the beginning of the twenty-first century, has witnessed exponential expansion over the last decade. The recent rapid advances in modern computing and information technology have given rise to more new digital tools and methods, including hypermedia, data visualization, text mining and digital mapping, and so on, all of which have been applied in DH to foster systematic and scholarly study of these digital resources. Such a study has a distinctive interdisciplinary nature.
Ecotech, Alienation, and Science Realism in the Chinese Cyborg Novel Waste Tide
Authors: Jiang Yuqin 
Published: January 2021

Abstract
There is a long list of Western cyberpunk fiction, but people seldom know that there is cyborg literature in China. Chen Qiufan's Waste Tide is an example of Chinese cyborg fiction. It exposes the cyborg's alienation from the development of high technology and a sick society. Mimi's cyborg transformation to be Mache-Mimi highlights body politics and biopolitics, which represents her deep oppression from hierarchy and patriarchy. It is a process of denaturalization and dehumanization. This novel represents a critical realism of global development and environmental protection. It uncovers the veil which hides the crime of global capitalism and its oppression on the developing countries. The suffering of Mimi exposes the potential robbing truth of global capitalism. Furthermore, it blames the slow violence and hegemony on the people on the lowest rung of society in the high-technology world. But the author expects humanitarianism to save this cyborg world. He follows humanitarianism and hopes that love will help people walk out of the trap of capitalism. It approves the value humanity should establish on the self- and social fulfilment. Technology and the existence of humans should be harmoniously connected and cooperate for realizing the wholeness of humanity.
EVALUACIÓN DE LAS CONDICIONES LABORALES DE LOS EGRESADOS DE CARRERAS TÉCNICAS UNIVERSITARIAS EN TELA, ATLÁNTIDA, HONDURAS
Authors: Marín González Oger Roberto 
Published: January 2021

El presente trabajo pretende evaluar las condiciones laborales de los egresados de carreras técnicas universitarias en Tela, Atlántida, Honduras y la relación que existe entre la condición laboral, la pobreza objetiva y la pobreza subjetiva. Esta investigación tiene un enfoque mixto ya que se hacen análisis de datos cuantitativos y cualitativos, el trabajo es de tipo exploratorio. Por otra parte, se hace uso del paquete estadístico SPSS para el cálculo de coeficientes de correlación entre las variables, los datos fueron obtenidos mediante la aplicación de una encuesta estructurada a través de la plataforma de Google Docs. El estudio concluye que las carreras técnicas universitarias en Tela han contribuido a mejorar el acceso al mercado laboral de los egresados, pero no influye en la mejora de la calidad de dichos empleos. Por otra parte, la pobreza subjetiva muestra menores niveles en comparación con la pobreza objetiva, el hecho de poseer un empleo influye en la percepción de la pobreza en los egresados de carreras técnicas universitarias en Tela.
Thymic stromal lymphopoietin production in DN32.D3 invariant natural killer T (iNKT) cell line and primary mouse liver iNKT cells
Authors: Choi Jun-Pyo , Woo Yeon Duk , Losol Purevsuren , Kim Sae-Hoon , Chang Yoon-Seok 
Published: January 2021

Background
Invariant natural killer T (iNKT) cells are known as the fast responder in allergic inflammation and the source of interleukin (IL)-4, IL-13, and interferon-gamma. Absence of iNKT cells down-regulated thymic stromal lymphopoietin (TSLP) production at the early stage of type 2 immune responses in the airway. However, it has not been reported whether iNKT cells are able to produce TSLP via stimulation of T-cell receptor (TCR).

Objective
We aimed to evaluate TSLP production from iNKT cells by TCR specific stimulations with anti-CD3/CD28 antibodies and α-galactoceramide (α-GalCer).

Methods
DN32.D3 iNKT cell line was stimulated with anti-CD3/CD28 antibodies, and TSLP production was measured in culture supernatants. Next, to confirm the TSLP production in primary mouse iNKT cells, the cells were sorted using α-GalCer-CD1d tetramer from mouse liver, and stimulated with anti-CD3/CD28 antibodies and α-GalCer. Then, cytokine productions were evaluated by enzyme-linked immunosorbent assay and quantitative polymerase chain reaction.

Results
TCR specific stimulation in DN32.D3 cells induced TSLP production as well as signature cytokines of iNKT cells. On the other hand, isolated primary mouse iNKT cells from liver did not show any induction of TSLP by TCR specific stimulations including anti-CD3/CD28 antibodies and α-GalCer, on the contrary to other cytokines.

Conclusion
This study suggested the possibility of TSLP production in iNKT cells, especially from DN32.D3 although primary mouse liver iNKT cells showed a different result.
Entrepreneurship Education and Venture Intention of Female Engineering Students in A Nigerian University
Authors: Peter Fred , Eze Sunday , Osigwe Kelechi , Peter Adeshola , Adeyemi Emmanuel , Okologbo Chibogu , Asiyanbola Temitope 
Published: January 2021

The significant changes taking place in the world have offered new opportunities for male and female-owned businesses. This study investigated the impact of entrepreneurship education and venture intention of female engineering students in Nigeria. A descriptive research design was used. Copies of the questionnaire were distributed to collect quantitative data on the link between entrepreneurship education and venture intentions of Landmark university female engineering students. The sample size for this study was determined based on the entire population of 32. This study used purposive random sampling techniques for the selection of the respondent. Hence, each participant was given an equal chance of being chosen from the population in no particular order. Regression analysis was used to analyse the stated hypotheses through a statistical package for social science (SPSS). The findings revealed that effective implementation of entrepreneurship education elements stimulate students’ entrepreneurial activities, particularly among female engineering students. This study advanced knowledge and concluded that entrepreneurship education elements such as pedagogy, educators’ competence, and learning environment have a significant impact on venture intention.
Agreement in Pathologic Interpretation of Liver Biopsy Specimens in Posttransplant Hepatitis C Infection
Authors: Younossi Zobair M. , Boparai Navdeep , Gramlich Terry , Goldblum John , George Peggy , Mayes James 
Published: January 2021

Abstract
Hepatitis C virus–related disease is rapidly becoming the most common indication for orthotopic liver transplant (OLT) in the United States. Although post-OLT hepatitis C viremia is universal, 40% to 60% of patients develop recurrent chronic hepatitis C. Distinguishing recurrent chronic hepatitis C infection from acute rejection may be difficult because of overlapping histopathologic features. To improve our diagnostic accuracy we undertook a study to determine interobserver and intraobserver agreement between pathologists examining post-OLT liver biopsy specimens in patients from our transplant database. Clinical data and microscopic sections from 26 patients with hepatitis C virus–related OLT were reviewed. Biopsy specimens were obtained because of abnormal liver enzymes (21/26) or routine post-OLT follow-up (5/26), representing both early (18 ± 11 days) and late (252 ± 206 days) post-OLT periods. Unidentified sections were examined by an experienced pathologist in a randomly assigned order and reexamined 6 weeks later in the same fashion by the initial reviewer and a second experienced pathologist. Interobserver and intraobserver agreement was calculated using κ statistic. The intraobserver agreement was 81% with a κ coefficient of 0.67 (P = .001). The interobserver agreement was 78% with a κ coefficient of 0.60 (P &lt; .001). The early post-OLT biopsy specimens (18 ± 11 days) were the most difficult to interpret.
Intrapericardial Yolk Sac Tumor Associated With Acute Myocarditis
Authors: Sicari Marie C. , Fyfe Billie , Parness Ira , Rossi Anthony , Unger Pamela 
Published: January 2021

Abstract
An occult intrapericardial yolk sac tumor occurred in a 3-year-old girl with a fatal outcome. At autopsy, a 5.5-cm mass surrounded the base of the heart and compressed the left atrium posteriorly. Histologically, the tumor was a pure yolk sac tumor. Postmortem chemical analyses of the blood revealed an α-fetoprotein level greater than 7000 μg/L. Acute myocarditis of both ventricles was also found.
Recommended Policies for Uses of Human Tissue in Research, Education, and Quality Control
Authors: Grizzle William , Grody Wayne W. , Noll Walter W. , Sobel Mark E. , Stass Sanford A. , Trainer Thomas , Travers Henry , Weedn Victor 
Published: January 2021

Abstract
As recipients of tissue and medical specimens, pathologists and other medical specialists regard themselves as stewards of patient tissues and consider it their duty to protect the best interests of both the individual patient and the public. The stewardship of slides, blocks, and other materials includes providing, under appropriate circumstances, patient materials for research, education, and quality control. The decision to provide human tissue for such purposes should be based on the specific (ie, direct patient care) and general (ie, furthering medical knowledge) interests of the patient and of society. The same standards of responsibility should apply to all medical professionals who receive and use specimens. This document proposes specific recommendations whereby both interests can be fostered safely, ethically, and reasonably.
Reference Standardization and Analytical Performance of a Liquid Homogeneous High-Density Lipoprotein Cholesterol Method Compared With Chemical Precipitation Method
Authors: Halloran Paul , Roetering Hinke , Pisani Thomas , van den Berg Bea , Cobbaert Christa 
Published: January 2021

Abstract
Background.—The use of high-density lipoprotein cholesterol (HDL-C) levels as a risk factor for coronary heart disease necessitates an accurate and precise method for measuring HDL-C. The Centers for Disease Control and Prevention HDL-C reference method (RM) and designated comparison method (DCM) are time-consuming, expensive, and impractical for routine clinical use. We evaluated the Liquid N-geneous (LN-gen) HDL-C assay (Genzyme Diagnostics, Cambridge, Mass) to determine if this homogeneous reagent meets the National Cholesterol Education Program requirements for HDL-C evaluation.
Design.—Accuracy of the LN-gen HDL-C assay was compared in combination with phosphotungstic acid (PTA) precipitation with DCM HDL-C for normotriglyceridemic serum specimens (triglycerides &lt;2.0 g/L) and with RM HDL-C for specimens with triglycerides levels ≥2.0 g/L.
Setting.—Genzyme Diagnostics (with RM and DCM assayed by Pacific BioMetrics Inc, Seattle, Wash) and the Lipid Reference Laboratory of the University Hospital Rotterdam, The Netherlands.
Results.—Linear regression to DCM (n = 90) was (LN-gen = 1.015 DCM + 0.01 g/L, r = 0.993, SE = 0.015 g/L) and (PTA = 1.004 DCM − 0.017 g/L, r = 0.980, SE = 0.025 g/L), with a mean percent bias to DCM of 3.3% and −2.8% for LN-gen and PTA, respectively. The comparison with RM (n = 69) showed an increased mean bias for PTA (−5.8%) as compared with LN-gen (1.5%). The correlation and regression equations were (LN-gen = 1.020 RM − 0.002 g/L, r = 0.985, SE = 0.017 g/L) and (PTA = 1.042 RM − 0.032 g/L, r = 0.984, SE = 0.018 g/L). The precision of LN-gen was confirmed at &lt;2.1% coefficient of variation, and the total error was calculated to be ≤7.7% for both normotriglyceride and elevated triglyceride specimens at HDL-C decision points of 0.35 g/L and 0.60 g/L.
Conclusions.—The LN-gen HDL-C assay offers a cost-effective convenient method for meeting the 1998 precision, bias, and total error recommendations of the National Cholesterol Education Program.
Sarcomatoid Collecting Duct Carcinoma
Authors: Fukunaga Masaharu 
Published: January 2021

Abstract
Background.—Collecting duct carcinoma has recently been recognized as a distinct entity among renal cell carcinomas and shows aggressive clinical behavior.
Design.—A fatal case of collecting duct carcinoma with sarcomatoid features in an 80-year-old man is described, and the results of immunohistochemistry and flow cytometric analysis are presented.
Results.—The tumor, which was white and had infiltrating margins in the cortex and medulla, consisted of adenocarcinomatous and sarcomatous components. The adenocarcinomatous component was characterized by tubular arrangement of atypical cells with high-grade nuclear features and desmoplastic stroma. The sarcomatous component had a malignant fibrous histocytoma-like appearance. The tumor cells in the adenocarcinomatous area were positive for cytokeratin 19, Ulex europaeus agglutinin I, peanut agglutinin, and soybean agglutinin. The tumor was DNA diploid. The patient died of disease 3 months after diagnosis.
Conclusion.—This study suggests that sarcomatoid collecting duct carcinoma may be one of the most aggressive tumors of the kidney.
The Antigenic Heterogeneity of the Bile DuctEpithelium in Alcoholic Liver Disease
Authors: Chedid Antonio , Mendenhall Charles L. , Moritz Thomas E. 
Published: January 2021

AbstractThe chronic alcoholic patient is usually immunosuppressed, but the significance of this phenomenon in terms of bile duct injury is unclear. The immunoreactivity of the bile duct cells was examined in a series of 69 frozen liver biopsy specimens obtained from patients with alcoholic liver disease, comprising 29 cases of cirrhosis, 26 of alcoholic hepatitis, 10 cases of alcoholic fatty liver, and 4 specimens from normal livers. Liver diseases such as primary biliary cirrhosis and human hepatic allograft rejection, known to have an autoimmune basis, share the characteristic feature of damage to the bile duct epithelial cells. In both instances the damage seems to be immune mediated, but the nature of the antigens involved is not established. We used the avidin-biotin-peroxidase complex method to test in alcoholic liver disease for the expression of a battery of surface antigen markers that have been incriminated in tissue injury and are usually present in lymphoid cells but also expressed by epithelium. In this study we investigated the expression of the following molecules: HLA class I (ABC) and class II (HLA-DR, HLA-DP, HLA-DQ), CD29, CD45RA, CD45RO, CD56, interleukin 1 (IL-I), IL-2, IL-4, interferon (IFN-γ), tumor necrosis factor β, and transforming growth factor β1 (TGF-β1). The bile duct epithelial cells strongly expressed HLA-ABC in all cases, CD56 in 47 of 55, IL-4 in 15 of 41, TGF-β1 in 14 of 25, and CD29 in 4 of 25 cases. The other markers including IFN-γ, HLA-DR, HLA-DP, and HLA-DQ were not expressed by bile duct cells. The expression of HLA class I agrees with previous observations while the absence of class II expression does not. The expression by the bile duct epithelium of CD56 confirms our own previous report. A new observation is the finding of molecules such as IL-4, TGF-β1, and CD29 strongly expressed in the bile ducts cells. The presence of these molecules, taken together with the lack of IFN-γ expression, contradicts previous speculations that attributed to IFN-γ a role in the induction of major histocompatibility antigens and adhesion molecules in immune-mediated alcoholic liver disease.
Metanephric Adenoma–like Tumors of the Kidney: Report of 3 Malignancies With Emphasis on Discriminating Features
Authors: Pins Michael R. , Jones Edward C. , Martul E. Vazquez , Kamat Brinda R. , Umlas Joel , Renshaw Andrew A. 
Published: January 2021

Abstract
Background.—Metanephric adenoma is a very rare benign renal tumor; only 80 well-documented cases have been reported to date. We have seen several renal tumors that were originally incorrectly diagnosed as metanephric adenoma.
Design.—We present 3 unusual renal tumors (2 primary and 1 metastatic), each of which illustrates important pathologic features useful in discriminating metanephric adenoma from malignant mimics.
Results.—Case 1 involved a 46-year-old man with multiple small, cortical, solid, papillary (chromophil) renal cell carcinomas in his right kidney; the patient developed multiple, histologically identical, solid, papillary (chromophil) carcinomas in the opposite kidney 17 months later. Case 2 involved a 32-year-old woman with a 14-cm right renal tumor who developed soft tissue and bone metastases over a 17-year period. Case 3 involved a 52-year-old woman who presented with a 1.8-cm corticomedullary renal nodule, which eventually proved to represent a metastasis from a poorly differentiated (insular) carcinoma of the thyroid. All 3 tumors superficially resembled metanephric adenoma and consisted of primitive, dark-staining cells arranged in tubules or sheets. Each tumor, however, also had features inconsistent with the diagnosis of metanephric adenoma, including multifocal lesions with a variable nuclear-cytoplasmic ratio and diffuse cytokeratin 7 and epithelial membrane antigen immunopositivity in case 1, a 14-cm-diameter tumor with occasional mitoses in case 2, and a distinct fibrous capsule with capsular and vascular invasion in case 3. In addition, all 3 tumors lacked the cytologic features of bland overlapping nuclei with imperceptible cytoplasm consistently seen in metanephric adenoma.
Conclusion.—Adherence to strict histopathologic criteria will discourage misdiagnosis of a malignant or potentially malignant renal neoplasm as the rare and always benign metanephric adenoma.
Biliary Lymphoepithelioma-like Carcinoma Not Associated With Epstein-Barr Virus
Authors: Kim Young-Bae , Park Young-Nyun , Han Jee-Young , Hong Ki-Chun , Hwang Tae-Sook 
Published: January 2021

Abstract
We report the case of a 64-year-old man who presented with a hepatic mass and macronodular cirrhosis. The pathologic findings revealed a lymphoepithelioma-like carcinoma arising in the hepatobiliary tract that was morphologically identical to nasopharyngeal undifferentiated carcinoma. However, this tumor was not associated with Epstein-Barr virus infection in molecular studies. Macronodular cirrhosis associated with hepatitis C virus was present in the background liver.
Requirements for Accreditation by the College of American Pathologists Laboratory Accreditation Program
Authors: Hamlin William B. 
Published: January 2021

Abstract
The College of American Pathologists Laboratory Accreditation Program expects a participant laboratory or laboratory section to be able to demonstrate that it is in compliance with the Standards for Laboratory Accreditation. The program expects laboratories to demonstrate that they are continually taking steps to identify and correct deficient areas and improve performance, in compliance with the Clinical Laboratory Improvement Amendments of 1988 regulatory requirements, particularly those pertaining to proficiency testing performance, and participating as inspectors in the accreditation process.
Health Care Financing Administration/Clinical Laboratory Improvement Amendments of 1988
Authors: Wanamaker Virginia 
Published: January 2021

Abstract
The Health Care Financing Administration has introduced new concepts for the Clinical Laboratory Improvement Amendments of 1988 survey program. Surveyors now look at the laboratory as a whole as opposed to each regulatory requirement independently. This quality assurance approach allows the surveyor to assess the laboratory's ability to provide quality test results as well as identify and correct its own problems. Significant problems in laboratories are more easily identified using this method. Another new concept allows good performing laboratories to go longer between on-site surveys by completing a self-assessment questionnaire on alternate cycles. The Health Care Financing Administration is asking both surveyors and laboratories to evaluate these new approaches. The Health Care Financing Administration continues to work with the Food and Drug Administration through our Memorandum of Understanding to assess Food and Drug Administration requirements in hospitals and laboratories that provide transfusion services. Transfusion-related fatalities must be reported to the Food and Drug Administration and may be investigated by either the Health Care Financing Administration or the Food and Drug Administration. For fatalities needing investigation by both agencies, every effort will be made to conduct these jointly.
Immunohistochemical Profile of Myogenin and MyoD1 Does Not Support Skeletal Muscle Lineage in Alveolar Soft Part Sarcoma
Authors: Gómez JoséA. , Amin Mahul B. , Ro Jae Y. , Linden Michael D. , Lee Min W. , Zarbo Richard J. 
Published: January 2021

Abstract
Background.—The histogenesis of alveolar soft part sarcoma remains elusive. Myogenic origin is favored, although conflicting data on immunohistochemical demonstration of muscle-associated markers exist. Myogenin and MyoD1, transcription factors of the myogenic determination family, have crucial roles in commitment and differentiation of mesenchymal progenitor cells to myogenic lineage and in maintenance of skeletal muscle phenotype. Their immunohistochemical detection is specific in characterization of rhabdomyosarcoma.
Methods.—Antibodies for myogenin, MyoD1, desmin, and muscle-specific actin were employed on a large series of cases (n = 19) of formalin-fixed, paraffin-embedded alveolar soft part sarcoma.
Results.—Minimal scattered nuclear staining was seen with myogenin. All cases had pronounced, nonspecific granular cytoplasmic immunostaining with MyoD1; nuclei were negative. All tumors were negative for desmin and muscle-specific actin. Ultrastructural study in 10 cases failed to reveal features of skeletal muscle differentiation.
Conclusions.—Cytoplasmic staining with MyoD1 in alveolar soft part sarcoma may correspond to cross-reactivity with an undetermined cytoplasmic antigen. The lack of immunostaining with myogenin, MyoD1, desmin, and muscle-specific actin provides evidence against a myogenic origin for alveolar soft part sarcoma.