bluuebunny/crossref_metadata_2025_split huggingface dataset:
Benefit of 18F-FDG PET/CT in Treatment Naïve Nasopharyngeal Carcinoma
Authors: Yang Shan-Shan , Wu Yi-Shan , Chen Wei-Chao , Zhang Jun , Xiao Su-Ming , Zhang Bao-Yu , Liu Zhi-Qiao , Chen En-Ni , Zhang Xu , OuYang Pu-Yun , Xie Fang-Yun 
Published: June 2021

Abstract
Background
We aimed to testify the advantage of positron emission tomography and computed tomography(PET/CT) in diagnosing cervical lymph nodes and staging nasopharyngeal carcinoma, and investigate whether PET/CT could bring about benefit in survival and serve for individualized treatment.
Methods
A total of 2759 patients were enrolled in this study. 460 biopsied cervical lymph nodes were named cohort A. Cohort B consisted of 1093 T3N1M0 patients who received both PET/CT and magnetic resonance imaging(MRI), while Cohort C contained 1377 T3N1M0 patients who underwent MRI alone. Cohort D enrolled 838 patients receiving concurrent chemoradiotherapy(CCRT) with or without induction chemotherapy(IC) to develop radiologic score model to guide IC.
Results
In cohort A, the sensitivity, accuracy, and area under the curve of PET/CT were much higher than those of MRI (96.7%versus88.5%, p < 0.001; 88.0%versus81.1%,p < 0.001; 0.863versus0.796,p < 0.05) in diagnosing metastatic lymph nodes. In cohort B, MRI staged T3N0-3M0 patients showed non-different survival rates, as they were the same T3N1M0 if staged by PET/CT. Besides, patients staged by PET/CT + MRI showed higher survival rates than those staged by MRI alone(p < 0.05), regardless of the Epstein–Barr virus DNA load. Interestingly, SUVmax-N, nodal necrosis and extranodal extension were highly predictive of survival. Radiologic score model based on these factors performed well(C-index = 0.72) in risk stratification. The identified high-risk patients undergoing IC + CCRT had higher 5-year failure-free survival than those receiving CCRT alone(p = 0.0064).
Conclusion
PET/CT showed advantage in staging by accurate diagnosis of lymph nodes and contributed to survival benefit. PET/CT carried prognostic factor could identify high-risk patients and guide individualized treatment.
Smart Computational Light Microscopes (SCLMs) of Smart Computational Imaging Laboratory (SCILab)
Authors: Fan Yao , Li Jiaji , Lu Linpeng , Sun Jiasong , Hu Yan , Zhang Jialin , Li Zhuoshi , Shen Qian , Wang Bowen , Zhang Runnan , Chen Qian , Zuo Chao 
Published: June 2021

Abstract
Computational microscopy, as a subfield of computational imaging, combines optical manipulation and image algorithmic reconstruction to recover multi-dimensional microscopic images or information of micro-objects. In recent years, the revolution in light-emitting diodes (LEDs), low-cost consumer image sensors, modern digital computers, and smartphones provide fertile opportunities for the rapid development of computational microscopy. Consequently, diverse forms of computational microscopy have been invented, including digital holographic microscopy (DHM), transport of intensity equation (TIE), differential phase contrast (DPC) microscopy, lens-free on-chip holography, and Fourier ptychographic microscopy (FPM). These computational microscopy techniques not only provide high-resolution, label-free, quantitative phase imaging capability but also decipher new and advanced biomedical research and industrial applications. Nevertheless, most computational microscopy techniques are still at an early stage of "proof of concept" or "proof of prototype" (based on commercially available microscope platforms). Translating those concepts to stand-alone optical instruments for practical use is an essential step for the promotion and adoption of computational microscopy by the wider bio-medicine, industry, and education community. In this paper, we present four smart computational light microscopes (SCLMs) developed by our laboratory, i.e., smart computational imaging laboratory (SCILab) of Nanjing University of Science and Technology (NJUST), China. These microscopes are empowered by advanced computational microscopy techniques, including digital holography, TIE, DPC, lensless holography, and FPM, which not only enables multi-modal contrast-enhanced observations for unstained specimens, but also can recover their three-dimensional profiles quantitatively. We introduce their basic principles, hardware configurations, reconstruction algorithms, and software design, quantify their imaging performance, and illustrate their typical applications for cell analysis, medical diagnosis, and microlens characterization.
Electrical Properties of PZT Under High-Pressure Stress Pulse Effects of Loading Frequency and Circuit Load
Authors: Wang Ruizhi , tang enling , Yang Guolai , Han Yafei , Chen Chuang , Chang Mengzhou , Guo Kai , He Liping 
Published: June 2021

Abstract
The research on the discharge characteristics of PZT under conventional applications has made good progress. In theory, the piezoelectric equation can be used to describe the relationship between stress and electrical output. However, existing studies have shown that the relationship becomes nonlinear under high-pressure stress pulses. To study the effect of loading frequency and circuit load on the electrical output performance of PZT under high-pressure stress pulse, the experiment was carried out based on the split Hopkinson pressure bar and a dynamic & static universal test machine. The effects of different circuits load on the output voltage under high-frequency and low-frequency high-pressure stress pulses are analyzed. Both theory and experiments prove that the critical open-circuit measurement resistance (Rcritial) of PZT decreases with the load frequency. The output voltage is positively correlated with the load resistance when the load resistance is less than Rcritial. It is confirmed by loading different circuits (diodes are added in different positions) that reverse positive charge appears at the negative pole of the material during the stress unloading stage. PZT have the maximum dischargeable strain Tunder the high-pressure stress pulses. PZT no longer generates induced charges when the strain is greater than h. When constant strain rate loading makes PZT completely release energy, its open-circuit output voltage is proportional to the strain rate.
Enhanced Ammonia Sensing By Cost-Effective ZnO Thin Films Through Yttrium Doping
Authors: Ravichandran K. , Santhosam A. Jansi , Omar M. Aldossary , Ubaidhulla Mohd 
Published: June 2021

Abstract
Yttrium (Y) doped (doping concentration - 0, 1, 3 and 5 wt%) ZnO thin films were deposited using spray pyrolysis technique. The structural, surface morphological, optical and compositional properties were analysed using X-Ray diffraction (XRD), Atomic Force Microscopy (AFM), UV-vis NIR spectrophotmetry (UV), photoluminescence study (PL) and elemental composition analysis. Ammonia vapour sensing properties such as response/recovery, stability and repeatability were studied at room temperature. XRD results confirmed that the prepared samples have hexagonal wurtzite structure. ZnO:Y thin film with 5 wt% yttrium doping exhibits excellent sensing response of 99, fast response/recovery times of 29 s/ 7 s which may be due to the existence of oxygen vacancies in the case of ZnO:Y (5 wt%) film sample confirmed by photoluminescence (PL) study. These oxygen vacancies attract more electrons and thus enhance the gas sensing. In addition, increase in the number of active sites caused by the substitution of Y3+(trivalent) ions into the Zn2+ (divalent) regular sites as confirmed by the observed M-B (Moss-Burstein) effect also causes an enhancement in the gas sensing. Surface roughness, another reason for the enhanced sensitivity, has been confirmed by AFM.
Effect of de-trending climatic parameters on temporal changes of reference evapotranspiration in the eastern Himalayan region of Sikkim, India
Authors: Pandey Vanita , Taloh Indira , Pandey P. K. 
Published: June 2021

AbstractReference Evapotranspiration (ET0) is an essential factor in irrigation scheduling, climate change studies, and drought assessment. The study's main objective was to identify the influences of detrending input climatic parameters (CPs) on ET0 using linear and nonlinear approaches throughout 1980–2015 in Gangtok, East Sikkim, India. The benchmark values of ET0 were calculated using the global standard FAO56 Penman–Montieth equation. The ET0-related CPs included for the analysis are maximum temperature (Tmax), minimum temperature (Tmin), maximum relative humidity (RHmax), minimum relative humidity (RHmin), and sunshine duration (SSH). The linear and nonlinear trends in various CPs affect ET0 change. Linearly detrended series was obtained by linear regression method whereas, nonlinearly detrended series was obtained using the Complete Ensemble Empirical Mode Decomposition with Adaptive Noise method. Twenty-three scenarios, including the original scenario, 11 scenarios in Group 1 (CPs de-trended linearly), and 11 scenarios in Group 2 (CPs de-trended nonlinearly) were generated. Influences of Tmax and SSH were more substantial than the influences of other CPs for both Group 1 and Group 2. The SSH masked the weak influence of other CPs. The effects of the trends in CPs, especially of SSH and Tmax, were clearly shown. The ET0 values decreased significantly during 1980–2015; however, no significant decreasing trend was observed in the case of SSH, during the same period. The nonlinear detrending gave closer results to the benchmark values as compared to linear detrending because of non-monotone variations of the ET0 and CPs. Therefore, the results from nonlinear detrending were more plausible as compared to linear detrending. The diminishing trend of ET0 prompted an overall alleviation of the dry spell, hence there would be a somewhat lower risk of water use in the study region.
Nutrient's response to water transfer in an urban river-network
Authors: Wang Hua , Liu Zhiqi , Feng Xiangyu , Yuan Weihao , Zeng Yichuan 
Published: June 2021

Abstract
Through water transfer, the hydrodynamic conditions of the river network can be improved, and the biochemical degradation of pollutants can be promoted, but at the same time, the endogenous release may be intensified. It is therefore possible to subdivide the response of nutrient content to water transfer into three components: (a) Direct Impact (DI) of dilution through water diversion, (b) Indirect Impact (II) by sediment release, and (c) Self Impact (SI) of nutrient degradation and attenuation of nutrients. By combining field investigation, laboratory experiment, and numerical simulation, the contribution weight of DI, II, and SI to the change of nutrient concentration was quantitatively analyzed. The results show that: (1) in the upper reaches of the river network, II plays a leading role in that the weight is more than 75%, and increasing the amount of water diversion increases the nutrient content; (2) SI plays a leading role in the tributary of the central part of the river network, the weight is more than 60%, and when the auxiliary pumping station is opened, the weight of II is less than 1%; (3) in the southeast of the river network, the nutrient release rate is sensitive to the change of hydrodynamics, and the weight of II is more than 90%. The results of this study can provide a reference for the formulation of a comprehensive hydrodynamic water quality management control scheme in the urban river network.
Water quality assessment of East Kolkata Wetland with a special focus on bioremediation by nitrifying bacteria
Authors: Saha Mousumi , Sarkar Agniswar , Bandyopadhyay Bidyut 
Published: June 2021

Abstract
East Kolkata Wetlands (EKW) is designated as International Ramsar site and are the hotspot for large-scale wastewater aquaculture practices. However, the continued surveillance of physicochemical properties of water and application of an eco-friendly approach are essential to ensure safe aquaculture practices. In the present study, we assessed the seasonal variation in physicochemical parameters of water across EKW and investigated the role of nitrifying bacteria as probiotics. We statistically analyzed various physicochemical properties of water samples from EKW. Results of the statistical analysis indicated a significant variation in all the physicochemical parameters across the selected water bodies of EKW (p &lt; 0.01). We isolated and enumerated Nitrosomonas sp. and Nitrobacter sp. and assessed their ability to degrade trichloroethylene (TCE). The role of Nitrosomonas sp. and Nitrobacter sp. were further investigated and established through a small-scale experiment. Two microbial isolates, NSW3 and NBW2, displayed superior TCE degradation ability at pH 5, and the application of these strains as probiotics were found to improve the quality of water and survival rate of fishes in the treated experimental tanks. Our findings suggest that the application of the above mixed bacterial cultures in aquaculture could be an effective and environment-friendly approach for safe and productive aquaculture operations.
The Saudi Ministry of Health’s Twitter Communication Strategies and Public Engagement During the COVID-19 Pandemic: Content Analysis Study
Authors: Alhassan Fatimah Mohammed , AlDossary Sharifah Abdullah 
Published: June 2021

Background
During a public health crisis such as the current COVID-19 pandemic, governments and health authorities need quick and accurate methods of communicating with the public. While social media can serve as a useful tool for effective communication during disease outbreaks, few studies have elucidated how these platforms are used by the Ministry of Health (MOH) during disease outbreaks in Saudi Arabia.

Objective
Guided by the Crisis and Emergency Risk Communication model, this study aimed to explore the MOH’s use of Twitter and the public’s engagement during different stages of the COVID-19 pandemic in Saudi Arabia.

Methods
Tweets and corresponding likes and retweets were extracted from the official Twitter account of the MOH in Saudi Arabia for the period of January 1 through August 31, 2020. Tweets related to COVID-19 were identified; subsequently, content analysis was performed, in which tweets were coded for the following message types: risk messages, warnings, preparations, uncertainty reduction, efficacy, reassurance, and digital health responses. Public engagement was measured by examining the numbers of likes and retweets. The association between outbreak stages and types of messages was assessed, as well as the effect of these messages on public engagement.

Results
The MOH posted a total of 1393 original tweets during the study period. Of the total tweets, 1293 (92.82%) were related to COVID-19, and 1217 were ultimately included in the analysis. The MOH posted the majority of its tweets (65.89%) during the initial stage of the outbreak. Accordingly, the public showed the highest level of engagement (as indicated by numbers of likes and retweets) during the initial stage. The types of messages sent by the MOH significantly differed across outbreak stages, with messages related to uncertainty reduction, reassurance, and efficacy being prevalent among all stages. Tweet content, media type, and crisis stage influenced the level of public engagement. Engagement was negatively associated with the inclusion of hyperlinks and multimedia files, while higher level of public engagement was associated with the use of hashtags. Tweets related to warnings, uncertainty reduction, and reassurance received high levels of public engagement.

Conclusions
This study provides insights into the Saudi MOH’s communication strategy during the COVID-19 pandemic. Our results have implications for researchers, governments, health organizations, and practitioners with regard to their communication practices during outbreaks. To increase public engagement, governments and health authorities should consider the public’s need for information. This, in turn, could raise public awareness regarding disease outbreaks.
Contribution to the study of improving the aesthetics of the smile by repairing and reshaping the incisors with composite materials.
Authors: Stoica Alexandra Mihaela , Stoica Oana Elena , Kovacs-Ivacson Csinszka , Monea Monica Dana 
Published: June 2021

Abstract
Introduction. Dental aesthetics, although it seems something relative and difficult to evaluate, it is governed by a series of laws and rules that connect the dental disciplines, creating a unitary whole. It is structured by rules, perfected by artistic sense and by the inclination towards beauty of all specialists in dento-facial cosmetics.
The aim of the study is to highlight an overview of aesthetic factors to consider when restoring anterior teeth with direct composite materials.
Material and methods. A total of 25 patients were included in the study where the anterior teeth were restored using Gradia Direct Anterior (from GC) and Filtek Z550 (from3M-ESPE) composite kits, in perfect isolation using rubber damn, with a separate appointment after 24 hours for the polishing step, for which Rainbow Kit Technic and polishing Platina Hi-Gloss (from Prevest) paste were used. While the replacement of the tooth defect, we ensured that the composite increment, which we used should not be more than 2mm in thickness, and light cured for 20 seconds as the producer recommends. In none of all tooth shape modification (elongation in incisal zone) we did not modify the occlusion, by eliminating all premature contacts. All patients included in the study have signed the informed consent and agreed to participate in this research.
Results. From a total of 25 patients, we repaired 20 central incisors with the mesial (18 cases) or distal (2 cases) angles fractured, in different accidents, 5 cases with diastema by small shape of the crown or malposition of one of the central incisors.
Conclusions. Restoring the incisal angle or the incisal edge and refining a natural and improved smile of the patient is e very frequent dental intervention, especially nowadays when aesthetics plays an important role in the social society.
Fear and dental anxiety in children: a study of the contributing factors.
Authors: Pasca Maria , Pazitor Andreea , Esian Daniela , Stoica Oana Elena , Stoica Alexandra Mihaela , Bica Cristina Ioana 
Published: June 2021

Abstract
Introduction: Dental fear and anxiety are an important issue affecting children’s oral health and clinical management, and also an insufficiently studied subject in dentistry.
Aim of the study: The aim of this study was to better understand the child patient - dentist versus dentist - child patient relationship and study the dental fear and anxiety of children in order to improve the dental office practice. Material and methods: In this study a personalized questionnaire was created and applied on a number of 333 children, in 4 schools from Mures county, Romania, on girls and boys between the ages of 8 and 13. The questionnaires used emoticons alongside words in order to better determine the state of anxiety created by the dental appointment and everything that it entails. All data and results obtained were analyzed using Excel and Graph Pad Prism 5.0 software.
Results: Out of 333 patients, 133 subjects (40%) were 8-10-year-old, 143 subjects (42.9%) 11 - 13 years and 57 subjects (17.1%) were over 14 years. 175 girls (52.6%) and 158 boys (47.4%) demonstrated their courage and desire in participating in our study. It was determined that fear of dental appointments was caused in children over 14 years of age. The state of relaxation is generally enjoyed by urban children (45%) and those aged 11-13 years (37.1%); the percentage of boys in this category is an interesting aspect (40.5%).
Conclusion: Dental anxiety is multifactorial and is far more complex than can be explained by a single contributing factor. The direct involvement of the child from the perspective of maintaining dental health, leads to the elimination of the state of fear and anxiety. Regular visits to the dental office, on the initiative of the child patient itself can reduce the anguish.
Inhibition of Haemoglobin Glycosylation, Glucose Uptake and In Vitro Antidiabetic Activities of Solvent Fractions from Daucus carota Seed
Authors: Tijjani Habibu , Imam Sadiq Adamu 
Published: June 2021

Abstract
Diabetes mellitus (DM) is a metabolic disorder which result from either absolute or relative insulin deficiency and may lead to dysfunction in some organ systems. Pancreatic α- glucosidase and α- amylase inhibition are an effective strategy to decrease levels of postprandial hyperglycemia through starch control breakdown. The aim of the study is to assess the in vitro antidiabetic activities of fractions from Daucus carota seed extract, a plant used traditionally for the treatment of diabetes mellitus. The aqueous extract (AQE) of Daucus carota seed was partitioned in ethyl acetate (EAE), n – hexane (HEX) and diethyl ether (DEE) to obtain the various fractions. The AQE and EAE expressed significant α – amylase inhibitory activity with IC50 values of 637.0±18.6 μg/mL and 603.0±25.8 μg/mL respectively. AQE, EAE, HEX and DEE expressed α – glucosidase inhibitory activity with IC50 value of 135.85±1.21, 147.59±0.57, 132.64±1.17, and 143.56±0.49 μg/mL respective compared with acarbose (ACA) with 5.42±0.20 μg/mL. Furthermore, DEE fraction expressed inhibitory effects on % glucose uptake in yeast cell comparable with metronidazole. All Daucus carota fractions expressed various inhibitory effects on haemoglobin glycosylation at a concentration of 200 – 1000 μg/mL. The results show that fractions from the aqueous seed extract of Daucus carota possess in vitro antidiabetic potentials with EAE and HEX fractions having most promising inhibitory activities against α-amylase and α-glucosidase respectively.
Can Corpus Consultation Compensate for the Lack of Knowledge in Legal Translation Training?
Authors: Giampieri Patrizia 
Published: June 2021

Abstract
It is generally assumed that a good knowledge of the legal field is a prerequisite to deliver legal translations. This paper will challenge this assumption by presenting a case study with third-year bachelor’s students who participated in a translation project. The students, enrolled in a course in translation practice, were trained in corpus consultation at the beginning of the academic year. Nearly at the end, they translated an extract of a supply contract without being trained in the legal field. They consulted a pre-compiled offline corpus and online bilingual dictionaries. The paper findings highlight that knowledge of the legal field would have certainly helped the students make more informed decisions and avoid some mistranslations. However, the major shortcomings were actually due to ineffective corpus or dictionary consultation. In particular, formulaic expressions and collocations were neglected. In light of the paper findings, it can be speculated that in translation training, effective corpus consultation may help users deliver high-quality legal translations. It also seemed that thorough knowledge of the legal field is not a prerequisite, at least as far as short texts are concerned.
Language- And Legal Culture Peculiarities in Selected Swiss Constitutional Acts Including a Translational Perspective
Authors: Iluk Łukasz 
Published: June 2021

Abstract
The subject of the analysis is linguaculture expressing linguistic and cultural differences occurring in every language of law. They relate to vocabulary and editing principles of law acts. It seems that preserving such differences in the target translation makes it possible to reveal specific legislation trends of a given country, which express political motivation. Their preservation in the translated text requires good knowledge of law and in-depth comparative analysis. The focus of the analysis in this text is on the expression of gender in the law texts and specifically, on the translation of feminatives and legal names relevant for cultural dimension of a given law system.