bluuebunny/crossref_metadata_2025_split huggingface dataset:
THREE LINKED ENZYME LOCI IN FISHES: IMPLICATIONS IN THE EVOLUTION OF VERTEBRATE CHROMOSOMES
Authors: Morizot Donald C , Wright David A , Siciliano Michael J 
Published: April 2021

ABSTRACT
A three-point linkage group comprised of loci coding for adenosine deaminase (ADA), glucose-6-phosphate dehydrogenase (G6PDH), and 6-phosphogluconate dehydrogenase (6PGD) is described in fish of the genus Xiphophorus (Poeciliidae). The alleles at loci in this group were shown to assort independently from the alleles at three other loci—isocitrate dehydrogenase 1 and 2, and glyceraldehyde-3-phosphate dehydrogenase 1. Alleles at the latter three loci also assort independently from each other. Data were obtained by observing the segregation of electrophoretically variant alleles in reciprocal backcross hybrids derived from crosses between either X. helleri guentheri or X. h. strigatus and X. maculatus. The linkage component of X2 was significant (&lt;0.01) in all crosses, indicating that the linkage group is conserved in all populations of both species of Xiphophorus examined. While data from X. h. guentheri backcrosses indicate the linkage relationship ADA—6%—G6PDH—24%—6PGD, and ADA—29%—6PGD (30% when corrected for double cross-overs), data from backcrosses involving strigatus, while supporting the same gene order, yielded significantly different recombination frequencies. The likelihood of the difference being due to an inversion could not be separated from the possibility of a sex effect on recombination in the present data. The linkage of 6PGD and G6PDH has been shown to exist in species of at least three classes of vertebrates, indicating the possibility of evolutionary conservation of this linkage.
BRICS countries and the construction of conflict in the Women, Peace and Security Open Debates
Authors: Hamilton Caitlin , Pagot Rhaíssa , Shepherd Laura J 
Published: April 2021

Abstract
The Women, Peace and Security (WPS) agenda is a diverse field of practice comprised of numerous actors, activities and artefacts. Conventional accounts of WPS development and implementation tend to reproduce a narrative that positions states located in the global North as ‘providers’ of WPS, and those in the South as ‘recipients’. This assumption in turn prescribes, and proscribes, forms of WPS engagement and has a constitutive effect on the agenda itself, as shown by post- and de-colonial analyses of the WPS agenda. This article seeks to explore the WPS practices of a group of states that in many ways challenge these North/South and provider/recipient binaries by explicitly positioning themselves as operating beyond and across them: the BRICS countries, comprised of Brazil, Russia, India, China and South Africa. In this article, we explore how constructions of conflict within the WPS practices of BRICS states relate to the acknowledgement of, and commitment to, the agenda more broadly. We ultimately argue that the BRICS' commitment to the WPS agenda is driven more by identity-making geopolitical considerations, including geostrategic interests, than a politics of peace.
MRI Features of Free Liquid Silicone in the Transgender Female Breast
Authors: Sonnenblick Emily B , Chaudhry Shivani , Lee Karen A , Jaffer Shabnam , Fang Frank , Ting Jess , Margolies Laurie R 
Published: April 2021

Abstract

Objective
To define MRI features of free liquid silicone injection (FLSI) of the breast in transgender women considering surgical management.

Methods
This study was IRB–approved. MRI images from transgender women with FLSI imaged between 2009 and 2019 were reviewed. Presence and location of fibrotic masses (FMs) in the breast(s) and pectoralis muscle and patterns of granulomas were correlated with clinicopathologic findings. Background enhancement was quantified. Comparisons were performed using two-tailed Fisher exact and Student’s t test.

Results
Of 21 transgender women with FLSI (mean age 46.8 years), 13/21 (61.9%) had a dominant FM measuring over 4 cm; these were limited to breast and pectoralis in 6/21 (28.6%), breast in 9/21 (42.9%), and pectoralis only in 2/21 (9.5%). Four of 21 patients (19.0%) had no FMs, and 4/21 (19.0%) had masses under 4 cm. Mean size of the dominant FM was 7.4 cm (range 4–12 cm). FMs were enhancing in 5/13 (38.5%) and contained T2 high signal granulomas in 8/13 (61.5%). While 18/21 (85.8%) of cases showed mild to moderate overall background enhancement, the majority 7/13 (61.5%) of dominant FM were non-enhancing. About half of cases (11/21, 52.4%) had diffuse foci, and half (10/21, 47.6%) had diffuse foci and masses throughout the breast and pectoralis muscle. These foci and masses displayed T2 high signal in 13/21 (61.9%). There were no occult carcinomas observed.

Conclusion
MRI performed on symptomatic FLSI patients considering surgical treatment is helpful in assessing the extent of silicone infiltration and fibrotic reaction of the breast and pectoralis muscle.
ABO Genetic Variation in Neanderthals and Denisovans
Authors: Villanea Fernando A , Huerta-Sanchez Emilia , Fox Keolu 
Published: April 2021

AbstractVariation at the ABO locus was one of the earliest sources of data in the study of human population identity and history, and to this day remains widely genotyped due to its importance in blood and tissue transfusions. Here, we look at ABO blood type variants in our archaic relatives: Neanderthals and Denisovans. Our goal is to understand the genetic landscape of the ABO gene in archaic humans, and how it relates to modern human ABO variation. We found two Neanderthal variants of the O allele in the Siberian Neanderthals (O1 and O2), one of these variants is shared with an European Neanderthal, who is a heterozygote for this O1 variant and a rare cis-AB variant. The Denisovan individual is heterozygous for two variants of the O1 allele, functionally similar to variants found widely in modern humans. Perhaps more surprisingly, the O2 allele variant found in Siberian Neanderthals can be found at low frequencies in modern Europeans and Southeast Asians, and the O1 allele variant found in Siberian and European Neanderthal is also found at very low frequency in modern East Asians. Our genetic distance analyses suggest both alleles survive in modern humans due to inbreeding with Neanderthals. We find that the sequence backgrounds of the surviving Neanderthal-like O alleles in modern humans retain a higher sequence divergence than other surviving Neanderthal genome fragments, supporting a view of balancing selection operating in the Neanderthal ABO alleles by retaining highly diverse haplotypes compared with portions of the genome evolving neutrally.
Introduction
Authors: Young Elliott 
Published: April 2021

Abstract
The introduction provides an overview of the broad sweep of immigrant incarceration from the late nineteenth century through the present. Although the number of immigrants in detention today based on immigration charges is higher than ever, if we consider all forms of incarceration, including mental asylums and people being imprisoned for drug and alcohol charges, the rates of institutionalization in the mid-twentieth century rival that of the last two decades. Furthermore, even though the Immigration and Naturalization Service policy shifted in the early to mid-1950s to paroling immigrants while they applied for asylum rather than detaining them, this was also the moment when hundreds of thousands of Mexicans were being detained for short periods of time and returned to Mexico. In the late 1980s and 1990s, criminal and immigration laws merged to mandate deportation for immigrants who had committed even minor offenses decades earlier.
Poll Vaulting
Authors: Phelps Charles E. , Madhavan Guru 
Published: April 2021

Abstract
This chapter provides a set of real-world examples of how the process used for decision-making dramatically affected the outcome and shows how different voting rules would have led to different choices. Examples include the 2000 U.S. presidential election (Bush vs. Gore, with Nader intervening) and the choice of finalist candidates in the 2016 U.S. presidential election (Clinton vs. Trump). It also includes a famous vote by 11 wine judges in France in 1976 (sometimes called “Judgment of Paris”), where we have the actual preferences of the judges. American wines won the blind taste-testing, shocking the French and eventually leading to the “democratization of the wine world . . . a watershed in the history of wine.” This chapter shows that even votes by small numbers of people can have significant effects and that the choice of voting method in part determined which wine “won” the contest.
Imagination and Reality
Authors: Wellman Henry M. 
Published: April 2021

Abstract
This chapter focuses on children’s ability to separate the imagined from the real and does so through a focus on imaginary companions. Imaginary companions appear in many forms; they can have physical forms (a puppet friend), or they can be purely mental creations. Typically, imaginary companions have ideas, emotions, and desires separate from the child’s, and thus they are saturated in theory-of-mind understandings. Although some authorities and many parents worry that imaginary companions are a particularly good example of children’s inability to separate the imagined from the real, research shows that young children easily distinguish between fantasy and fact, between the mental and the real, between imagined entities and real physical ones. Moreover, children who have imaginary companions not only distinguish between mind and reality, but also show numerous theory-of-mind strengths.
Illuminating the Mind
Authors: Stoltz Jonathan 
Published: April 2021

Abstract
This book provides readers with an introduction to epistemology within the Buddhist intellectual tradition. It is designed to be accessible to those whose primary background is in the “Western” tradition of philosophy and who have little or no previous exposure to Buddhist philosophical writings. The book examines many of the most important topics in the field of epistemology, topics that are central both to contemporary discussions of epistemology and to the classical Buddhist tradition of epistemology in India and Tibet. Among the topics discussed are Buddhist accounts of the nature of knowledge episodes, the defining conditions of perceptual knowledge and of inferential knowledge, the status of testimonial knowledge, and skeptical criticisms of the entire project of epistemology. The book seeks to put the field of Buddhist epistemology in conversation with contemporary debates in philosophy. It shows that many of the arguments and debates occurring within classical Buddhist epistemological treatises coincide with the arguments and disagreements found in contemporary epistemology. The book shows, for example, how Buddhist epistemologists developed an anti-luck epistemology—one that is linked to a sensitivity requirement for knowledge. Likewise, the book explores the question of how the study of Buddhist epistemology can be of relevance to contemporary debates about the value of contributions from experimental epistemology, and to broader debates concerning the use of philosophical intuitions about knowledge.
Inference
Authors: Stoltz Jonathan 
Published: April 2021

Abstract
This chapter introduces the Buddhist theory of inference. It begins with the distinction between “inference for oneself” and “inference for others,” and argues that what is of primary importance in epistemology is the category of “inference for oneself.” The chapter then lays out the standard features of the Buddhist account of inferential knowledge, including Dignāga’s appeal to “the three characteristics” of good evidence and Dharmakīrti’s account of three different types of evidence. The chapter concludes with a section on the topic of epistemic closure principles and how such principles might apply to Buddhist accounts of inferential knowledge.
Beatles Heritage Tourism in Liverpool
Authors: Brocken Michael 
Published: April 2021

Abstract
This chapter explores the tension between the Beatles’ story and Liverpool, with imagery and imagination conjuring up compelling beliefs that command narratives of authority. Such heritage strategies have smacked a little of desperation, perhaps masking the changed relationship between surviving Beatles fragments in Liverpool and popular-music heritage tourism across the globe. The rhetoric of the Beatles, Liverpool, and “the ’60s, man” today represents an outdated, white, gendered, anglophone rock meta-narrative in what is now a multifaceted global popular-music (tourism) marketplace. Liverpool’s position as the authentic site for Beatles and Merseybeat tourism and a World Heritage Site has never been more precarious. How can the city continue to attract Beatles tourists as the ’60sslip away into the annals of popular-music historiography? An additional question is how the Beatles’ legacy might be explained to visitors with little knowledge of them as a global popular-music phenomenon.
Artificial Intelligence in Health Care
Authors: Perakslis Eric D. , Stanley Martin 
Published: April 2021

Abstract
Although not always considered a domain of digital health, artificial intelligence (AI) and machine learning (ML) are inseparable, given that virtually all digital health tools utilize advance algorithm technologies. For example, a wearable device is not directly measuring sleep. It is measuring movement, electrical impulses, and other variables that are processed via algorithm and presented as a representation of sleep. Beyond digital devices, AI is being seen as a revolution in health care driven by the hopes that algorithms running on electronic medical record systems will predict when a patient is turning septic or that AI will free clinicians from tedious tasks. Much of this is coming true, but there is also a growing list of potential hazards such as trusting “black boxes,” racial bias, and poor technical execution. This chapter discusses ways to find the right balance between the progress and problems of AI in health care.
Floating Grandparents
Authors: Qi Xiaoying 
Published: April 2021

Abstract
The chapter supplements the conventional image of vulnerable “left behind” children and elderly in the villages and towns in China from which mobile young adults depart to seek employment in urban areas. By showing an increasing propensity of aged parents to provide childcare in the cities where their adult children are employed, it identifies an intergenerational dimension of the floating population of migratory workers. The chapter provides a more complete representation of internal migration and urbanization in contemporary China by examining the childcare provided by grandparents as a form of reproductive labor that enables the labor-force participation of their adult children and thus contributes to social reproduction. The change in the notions of family obligation initiated by young people has received much research attention; the chapter shows, however, that grandparents frequently initiate renegotiations of filial obligation. The chapter reconceptualizes intergenerational support by considering the importance of pre-exchange obligation, emotional attachment, and symbolic values in intergenerational interactions, factors conventional approaches typically ignore.
Crafting a New Compact in the Public Interest
Authors: Alexander Keith B. , Jaffer Jamil N. 
Published: April 2021

Abstract
Leaks of highly classified information, popular views of government national security efforts, and changes in the media environment in recent years have resulted in a significant decay in the relationship between the government and the media and public trust in both institutions. To correct this harmful trend, a significant recalibration of the government-media relationship and the establishment of a new compact between them would best serve the public interest. The government should be more transparent about its national security efforts and more self-critical in classification decisions and should explain national security activities it undertakes, defending and justifying classified programs in detail whenever possible. The press must likewise be willing to afford the government fair treatment, including noting government efforts to protect national security, and to appropriately balance civil rights and privacy. It is important that these institutions work together to establish new mores on classification, government transparency, and a more responsible approach to classified disclosures.
What We Owe Whistleblowers
Authors: Jaffer Jameel 
Published: April 2021

Abstract
The legal, political, and technological developments of the past twenty years have rendered us more reliant on whistleblowers even as the developments have made whistleblowing more difficult and more hazardous. To promote informed public debate about national security and to preserve the connection between democratic consent and government policy in this sphere, we should extend legal protection, in some circumstances, to government insiders who responsibly disclose official secrets without authorization. Affording leakers a “public value” defense against prosecution would have benefits beyond those usually cited. It would, among other things, reduce the disincentive to socially beneficial leaks, lend legitimacy to Espionage Act prosecutions, more closely align our legal regime with widely shared intuitions about moral responsibility, and restore the courts to an appropriately central role in protecting the public’s access to an essential channel of information.
Being and Freedom
Authors: Skorupski John 
Published: April 2021

Abstract
Being and Freedom is an account of ethics in Europe from the French Revolution: a phase of philosophical ethics whose influence ran far beyond philosophy, eventually dominating politics and religion in the West. Developments came from France, Germany, and Britain. This book is currently the only study that treats them together as a Europe-wide phenomenon. The first chapter covers the philosophical conflict at the heart of the French Revolution, between the individualism of the Enlightenment and two very different forms of holistic ethics: the old regime’s ethic of service and the radical-democracy of the Rousseauian left. Responses analysing modern freedom and democracy came from a series of French liberal thinkers. In Germany the reaction was to two revolutions seen as inaugurating modernity—the political revolution in France and the philosophical revolution of Kant. Here the fate of religion was critical; with it the metaphysics of being and freedom. The story is traced from Kant to Hegel’s idealist version of ethical holism. In Britain, Enlightenment naturalism remained the prevailing framework. It took different forms: ‘common sense’ and the theory of the sentiments in Scotland, utilitarianism in England. From these elements came a synthesis of European themes by John Stuart Mill—comparable in range but opposed to that of Hegel. This period’s ethical ideas remain the core of late modern ethics and the contested ground on which ethical disagreements take place today. The final chapter is a retrospective and assessment.
The renormalization group in curved space
Authors: Buchbinder Iosif L. , Shapiro Ilya L. 
Published: April 2021

Abstract
As the main purpose of renormalization is not to remove divergences but to get essential information about the finite part of effective action, this chapter discusses some of the existing methods of solving this problem; such methods can be denoted the renormalization group. First, the minimal subtraction renormalization group in curved space is formulated. Next, the chapter shows how the overall μ-independence of the effective action enables one to interpret μ-dependence in some situations. As an example, the effective potential is restored from the renormalization group and compared with the expression calculated directly in chapter 13. In addition, the global conformal (scaling) anomaly is derived from the renormalization group.
Introduction
Authors: Wyss Marco 
Published: April 2021

Abstract
After showcasing the discrepancy between Britain’s and France’s postcolonial security roles in Nigeria and Côte d’Ivoire, and Africa more generally, the introduction presents the major actors—Britain, France, Nigeria, and Côte d’Ivoire—their underlying motivations and positions, and how they were affected not only by global, but importantly also by local and regional circumstances. Therefore, and to set the scene for the comparative analysis of the making of the Anglo-Nigerian and Franco-Ivorian postcolonial security relationships, the introduction then provides an extensive discussion of Africa’s Cold War and African agency. Thereafter, it provides a discussion of sources and, finally, presents the architecture of the book.
Looking back and looking forward
Authors: Petchey Owen L. , Beckerman Andrew P. , Cooper Natalie , Childs Dylan Z. 
Published: April 2021

Abstract
After reading this book, what comes next? There is a lot that we decided to leave out of the book that we would have loved to put in. This chapter includes some pointers about what we left out, and what you could now start exploring. We also include a section on reproducibility, which covers the basics of what reproducibility is, why we might care about making our work reproducible, and what practical moves we can make towards achieving this.
Marks & Spencer
Authors: Murthy Sudhir Rama , Barry Mike , Ellis Justine Esta 
Published: April 2021

Abstract
The case of Marks & Spencer illustrates how a company has used a sustainability scorecard that awards provisional, bronze, silver, and gold ratings to participating suppliers to promote its sustainability programme. The scores are based on environment, human resources and ethical trade, and lean manufacturing. Suppliers undertake self-assessments of the scorecard at least once a year, which are subject to audit and assurance. The programme has delivered substantial savings through waste reduction and environmental efficiency amounting to over £600 million since 2007.
JD.com
Authors: Price Lydia J , Xiaowen Liu , Hua Ni Jing 
Published: April 2021

Abstract
JD.com is one of China’s largest e-commerce companies, capturing more than a quarter of the country’s $600 billion B2C market in 2017. It is seeking to become one of the world’s most trusted companies and is working with local farmers’ cooperatives, the Chinese, and a local internet business owner to create a programme called Running Chicken to source free-range chickens at scale from low-income farmers in Wuyi County in northern Hebei Province. JD buys chickens at three times the average market price provided that strict standards are adhered to and monitored. The result has been increased farmer incomes that have raised hundreds of families out of poverty and removed Wuyi County from the national poverty list. Pilots are underway to replicate the programme in other poverty-stricken counties of China.