bluuebunny/crossref_metadata_2025_split huggingface dataset:
Serial Change in Echocardiographic Parameters and Cardiac Failure in End-Stage Renal Disease
Authors: FOLEY ROBERT N. , PARFREY PATRICK S. , KENT GLORIA M. , HARNETT JOHN D. , MURRAY DAVID C. , BARRE PAUL E. 
Published: May 2021

Abstract.
Echocardiographic abnormalities are the rule in patients starting dialysis therapy and are associated with the development of cardiac failure and death. It is unknown, however, whether regression of these abnormalities is associated with an improvement in prognosis. As part of a prospective cohort study with mean follow-up of 41 mo, 227 patients had echocardiography at inception and after 1 yr of dialysis therapy. Improvements in left ventricular (LV) mass index, volume index, and fractional shortening were seen in 48, 48, and 46%, respectively. Ninety patients had developed cardiac failure by 1 yr of dialysis therapy. Twenty-six percent of the remaining 137 patients subsequently developed new-onset cardiac failure. The mean changes in LV mass index were 17 g/m2 in those who subsequently developed cardiac failure compared with 0 g/m2 among those who did not (P = 0.05). The corresponding values were -8 versus 0% for fractional shortening (P < 0.0001). The associations between serial change in both LV mass index and fractional shortening and subsequent cardiac failure persisted after adjusting for baseline age, diabetes, ischemic heart disease, and the corresponding baseline echocardiographic parameter. Regression of LV abnormalities is associated with an improved cardiac outcome in dialysis patients. Serial echocardiography adds prognostic information to one performed at baseline.
Comparison of Mortality Risk for Dialysis Patients and Cadaveric First Renal Transplant Recipients in Ontario, Canada
Authors: RABBAT CHRISTIAN G. , THORPE KEVIN E. , RUSSELL J. DAVID , CHURCHILL DAVID N. 
Published: May 2021

Abstract.
In population-based studies, renal transplantation has been shown to improve survival compared to dialysis patients awaiting transplantation in the United States. However, dialysis mortality in the United States is higher than in Canada. Whether transplantation offers a survival advantage in regions where dialysis survival is superior to that in the United States is uncertain. This study examines a cohort of 1156 patients who started end-stage renal disease (ESRD) therapy and were wait-listed for cadaveric renal transplantation in the province of Ontario, Canada between January 1, 1990 and December 31, 1994. Patients were followed from wait-listing for renal transplant (n = 1156), to cadaveric first renal transplant (n = 722), to death, or to study end (December 31, 1995). The annual crude mortality rates for wait-listed dialysis patients and transplanted patients were 5.0 and 3.4%, respectively. In Cox proportional hazards models, mortality in wait-listed patients was associated with increased age and diabetes, but not time from onset of ESRD to wait-listing. Factors associated with death following transplantation include older age, diabetes, and longer time spent on the waiting list before transplantation. In a time-dependent Cox regression model, the relative risk of death after transplantation compared to dialysis varied in a time-dependent manner. Covariates associated with increased risk included older age, diabetes, and time from onset of ESRD to wait-listing. The average relative risk (RR) of dying was 2.91 (95% confidence interval [CI], 1.34 to 6.32) in the first 30 d after transplantation, but was significantly lower 1 yr after transplantation (RR 0.25; 95% CI, 0.14 to 0.42), indicating a beneficial long-term effect when compared to wait-listed dialysis patients. This long-term benefit was most evident in subgroups of patients with diabetes (RR 0.38; 95% CI, 0.17 to 0.87) and glomerulonephritis (RR 0.13; 95% CI, 0.04 to 0.39) as the cause of ESRD. The survival advantage associated with renal transplantation is evident in this cohort of patients with a lower wait-listed dialysis mortality than that reported previously in the United States. The magnitude of the treatment effect is consistent across studies.
Elevated Levels of Serum Sulfite in Patients with Chronic Renal Failure
Authors: KAJIYAMA HIROSHI , NOJIMA YOSHIHISA , MITSUHASHI HIDEKI , UEKI KAZUE , TAMURA SHIGEO , SEKIHARA TETSUO , WAKAMATSU RYOUJI , YANO SHINTARO , NARUSE TAKUJI 
Published: May 2021

Abstract.
Sulfite, a well known air pollutant, is toxic for humans, especially those with sulfite hypersensitivity. Sulfite is also generated endogenously, during normal metabolism of sulfur-containing amino acids. Mammalian tissues contain the enzyme sulfite oxidase, which detoxifies both endogenous and exogenous sulfite by oxidation to sulfate. Deficiency of sulfite oxidase in humans is fatal, demonstrating its physiologic importance. Nevertheless, information about serum and tissue levels of sulfite in normal and pathologic conditions is limited. Using a sensitive HPLC assay, it is shown here that sera from patients with chronic renal failure (CRF) contain significantly higher amounts of sulfite than those from healthy subjects. Mean ± SD of serum sulfite in healthy subjects (n = 20) was 1.55 ± 0.54 μM, whereas those in patients under maintenance hemodialysis (HD patients; n = 44) and CRF patients before introducing dialysis therapy (pre-HD patients; n = 33) were 3.23 ± 1.02 μM (P < 0.01) and 3.80 ± 3.32 μM (P < 0.01), respectively. Among pre-HD patients, serum sulfite was positively correlated with serum creatinine (r = 0.714, P < 0.0001), and negatively with serum albumin (r = -0.407, P = 0.0188), hematocrit (r = -0.524, P = 0.0017), and total cholesterol (r = -0.375, P = 0.0318). There was no significant association between sulfite and patient age, gender, or leukocyte counts. Multiple regression analysis revealed serum creatinine as the sole independent predictor of serum sulfite levels. Each HD treatment was associated with approximately 27% reduction in serum sulfite levels, suggesting the presence of a dialyzable form in serum. Thus, these results indicate that reduced glomerular filtration is a factor that determines serum sulfite levels. Chronic elevation in serum sulfite levels might contribute to tissue or organ dysfunction in patients with CRF.
Effect of Uremia and Dialysis Modality on Mononuclear Cell Apoptosis
Authors: MARTÍN-MALO ALEJANDRO , CARRACEDO JULIA , RAMÍREZ RAFAEL , RODRIGUEZ-BENOT ALBERTO , SORIANO SAGRARIO , RODRIGUEZ MARIANO , ALJAMA PEDRO 
Published: May 2021

Abstract.
The aim of this study was to evaluate the effect of both uremia itself and hemodialysis (HD) membranes on the induction of apoptosis. Four groups of subjects were evaluated: 21 nondialyzed (Non-D) patients, 10 continuous ambulatory peritoneal dialysis (CAPD) patients, and 53 HD patients who were on hemophan, cuprophan, cellulose acetate, AN69, and polysulfone; control subjects were nine healthy volunteers. Circulating mononuclear cells were obtained before dialysis and cultured for 48 h. Mean percentage of apoptosis was analyzed by a FACScan flow cytometer using Annexin V-FITC. Cell apoptosis was increased in Non-D patients (11.5 ± 5.5%) compared with control subjects (2.1 ± 0.7%, P < 0.001) and CAPD patients (7.0 ± 5.8%, P < 0.05). In patients on HD with cuprophan, apoptosis was higher than in control subjects and Non-D and CAPD patients. In Non-D patients, apoptosis was inversely correlated with renal creatinine clearance (r = -0.62, P = 0.003). Cell apoptosis was higher in hemophan than the other HD membranes. In seven patients on hemophan, switching to polysulfone resulted in decreased apoptosis (P < 0.01). Mononuclear cell circulation through mini-dialyzers made of different types of membranes (cuprophan, hemophan, cellulose acetate, AN69, and polysulfone) prouced a significant increase in apoptosis. However, there was a marked difference in the percentage of apoptosis induced by these five membranes, being significantly increased in hemophan and cuprohan compared with the other three membranes. Similar results were obtained when whole blood from healthy donors was circulated through the mini-dialyzers, showing that mononuclear cell apoptosis was increased in hemophan and cuprophan compared with polysulfone. In conclusion, uremia and membrane characteristics may independently affect the mononuclear cell apoptosis.
A Discourse Analysis Study of Graffiti at Secondary Schools in Jordan
Authors: Ta'amneh Mohammad Abd Alhafeez Ali 
Published: May 2021

This research aims to explore the thematic meanings of graffiti written on the walls and desks at secondary public schools in the Directorate of Education for the Qasabat Irbid District during the second semester of the academic year 2020/2021. The data comprise 207 written graffiti taken from different locations. Braun and Clarke's (2006) Thematic Analysis and Fairclough's (1995) Critical Discourse Analysis are adopted to account for the data thematically and linguistically. The findings of the study show that the qualitative and quantitative data fall into three main discourse themes: Religious, Political, and Emotional. Each one has been classified into subcategories accordingly. The results also show that the highest percentage of the discourse theme domains is related to the emotional one which constitutes the half of data. The lexical features indicate that the language of the graffiti is simple. Yet, it presents a complete thought. Languages and language variations are also identified.
Ritual de dança e gastronomia como viés de educação ambiental numa comunidade negra do município de São Francisco do Conde-Bahia-Brasil
Authors: Santos da Paixão Angélica , Dacach Fernandez Marchi Cristina Maria , Dos Santos Edvaldo Hilário 
Published: May 2021

O presente trabalho expõe o resultado das ações da equipe de educação ambiental da Secretaria Municipal do Meio Ambiente, junto aos moradores da Ilha do Paty pertencente a Prefeitura de São Francisco do Conde-BA e ressalta a importância das ações de sensibilização ambiental entre os povos e comunidades tradicionais. Objetiva demonstrar uma experiência no campo da educação ambiental não formal, sugerida pela Política Nacional de Desenvolvimento Sustentável dos Povos e Comunidades Tradicionais, assim como, na Política Nacional de Educação Ambiental, baseada no tripé, diagnóstico, sensibilização e ações efetivas, num estudo de caráter descritivo, exploratório e bibliográfico, resultando num levantamento de impactos ambientais, seguido de momentos de reflexão e promoção de gestos concretos de reversão dos processos de geradores da degradação, culminando num processo gradativo de auto reconhecimento das atitudes degradadoras em relação ao ambiente local e às diversas possibilidades de minimização dos impactos gerados.
Conceptualización de la Hoja de vida de lector como instrumento de evaluación formativa en la educación superior
Authors: Ojeda-Avellaneda Ana Cecilia , Torres-Lizarazo David Fernando , Monsalve-Flórez Jhon Alexánder 
Published: May 2021

El objetivo de este artículo de investigación es conceptualizar la Hoja de vida de lector como instrumento de evaluación formativa al inicio de la Educación Superior. Con el fin lograr tal propósito, el Grupo de Investigación Cultura y Narración en Colombia (Cuynaco) se basa en el paradigma hermenéutico-interpretativo de las Ciencias Sociales y en el método documental de investigación con carácter proyectivo. Por tanto, se realiza, en primer lugar, una revisión de la literatura en torno a instrumentos de valoración metacognitiva; por la escasez de investigaciones al respecto, se propone una aproximación al análisis bibliométrico del tema y un diálogo entre los instrumentos de evaluación hallados. En segundo lugar, se expone una aproximación teórica alrededor de conceptos tales como Hoja de vida, Lector y Evaluación formativa. A partir de lo anterior, surge la definición de Hoja de vida de lector, como un instrumento metacognitivo con características formativas particulares en comparación con los existentes.
Remembering the Return from Exodus: An Analysis of a Salvadoran Community’s Local History Reenactment
Authors: Huezo Stephanie M. 
Published: May 2021

Abstract
On June 20, 1986, amid the 12-year civil war in El Salvador (1980–1992), a group of displaced Salvadorans from the northern department of Chalatenango declared San José las Flores their home. As the war between the Salvadoran army and the Farabundo Martí National Liberation Front (FMLN) intensified in rural areas, many people left to find refuge in other parts of the country. Since the FMLN had an active presence in Chalatenango, the Salvadoran military bombed this region frequently, which transformed las Flores into a ghost town by 1984. Those Salvadorans who decided to hide instead of leaving the country or even the region faced treacherous conditions as they trekked through the mountainous terrain of Chalatenango fleeing from military operations. By 1986, many of these Salvadorans emerged from their precarious living to demand their right to live in San José las Flores. More than three decades after the repopulation of the town, and more than two decades since the signing of the peace accords, residents of las Flores continue to celebrate their history, without fail, every year, bearing witness to a reenactment of the events that led to their town’s repopulation. This article examines these anniversaries, especially its 30th anniversary in 2016, to understand how the town remembers, interprets, and transforms their local history. What prompts residents of las Flores to relive these events? How is social memory and trauma transmitted to the diverse audience in attendance? What does reenactment have to do with collective memory? This article argues that the performance of the repopulation of las Flores, enacted by former guerrilla soldiers, survivors of the war, and their children and grandchildren, demonstrates how the history, memories, and values of this town are transmitted from generation to generation. In Diana Taylor’s words, they remember their collective suffering, challenges, and triumphs through both archival and embodied memory.
The Relationship Between Hyperplastic Gastric Polyps And Helicobacter Pylori
Authors: ERDAL Harun , SAKİN Yusuf Serdar , ÇETİN Mehmet , ÇELİK Bülent , ÖNMEZ Attila , UYGUN Ahmet , GÜLŞEN Mustafa 
Published: May 2021

Objective
Helicobacter pylori (H. pylori) is a gram-negative bacterium. It is urease positive, mobile, microaerophilic, and spiral-shaped, and it settles in the stomach and the proximal duodenum. It is associated with chronic gastritis, stomach ulcers, duodenal ulcers, stomach cancer, and MALT lymphoma. It can also cause premalignant lesions, such as metaplasia and gastric atrophy. Although several studies are investigating the correlation between H. pylori and hyperplastic polyps (HPs) of the stomach, uncertainty in this regard continues.
Methods
Data from 5378 patients who underwent esophagogastroduodenoscopy at the Department of Gastroenterology, Gülhane Training and Research Hospital,
University Of Health Sciences between October 2016 and March 2019 were retrospectively analyzed, and patients with gastric polyps were evaluated for polyp pathologies and normal mucosa biopsies.
Results
Sixty-one stomach polyps were detected in 49 patients after the retrospective analysis of the data between October 2016 and March 2019. Of the polyps found, 36 were hyperplastic (73%). There was no statistically significant difference between HPs and the presence of H. pylori, age, gender, anatomical location of polyps in the stomach, size, number, presence of metaplasia, or atrophy. The mean age was statistically lower in H. pylori-positive cases.
Conclusions
No correlation was observed between HPs and the presence of H. pylori. There is a need for more extensive, multi-centered, and prospective studies evaluating the relationship between HPs and H. pylori.
Turkish instrument educators' distance education experiences related to instrument training during the COVID-19 pandemic
Authors: Okay Hasan H. 
Published: May 2021

This research aims to determine distance education experiences of Turkish instrument educators’ related to instrument training during the COVID-19 pandemic. As with other practice lessons in education, instrument training also collides with its own unique problems during pandemic. Therefore, it is thought that the experiences of Turkish instrument educators regarding the process will create new discussions. The research was conducted by analyzing the findings obtained from semi-structured interviews with 14 participants with a phenomenological model. Considering the findings of the study, it can be seen that distance education conditions affect the instrument educators and the instrument training process both positively and negatively, and these effects bring some practices to the experience of instrument training permanently, possibly irreversible from now on. In the study, it was seen that an important source of the problems experienced by the instrument educators during the distance education process was related to technical facilities, such as connection speed and software.

Keywords: Musical instrument educators, musical instrument training, COVID-19, the pandemic, distance education.
The evaluation of intercultural professional technology-based communicative competence formation for students
Authors: Mikhailova Tatyana , Duisekova Kulyash , Orazakynkyzy Farida , Beysembaeva Gulshat , Issabekova Saule 
Published: May 2021

The purpose of the study is to determine the evaluation of the Intercultural Professional-Technology based communication Based Communicative Competence Formation of Students. Overall 22 respondents of the 2nd year at a State university took part in the research like focus groups. The results were taken by the interview in the Google forms. The results of the analyzes showed that the development of the intercultural professional-communicative competence of natural studies students is considered to be a very important requirement, and the formation of their professional communication skills can open up great opportunities for the future career of students. Students’ interview has also shown that from methodological aspect a case study technology-based communication is highly valued. Therefore, effective ways of using communicative-cognitive case technology-based communication in the classroom were analyzed and an algorithm for working with it was developed.

Keywords: Intercultural Professional Communicative Competence, technology based communication, cognitive, intercultural.
Digital transformation of Russian society as a condition of forming young teachers’ professional identity in a big city
Authors: Volkov Yury G. , Chikarova Galina I. 
Published: May 2021

Digitalization affects every sphere of life including education. However, for it to be beneficial, it needs transfomation in order to fit the current situation or changes that have occurred in human life over a time.The purpose of this research is to consider the impact of the digital transformation of Russian society on the formation of young teachers’ professional identity. The constructivist approach and the "soft concepts" of identity that have developed within its framework, serve as the methodological basis of the proposed research. The results of the applied authors’ sociological study conducted in 2020 serve as the empirical basis of this study. The method of collecting information was an in-depth interview. The reseach concluded that digitalization has a positive impact on formation of professional identity of young teachers. We also note that, despite the fact that the forced transition to online education has increased the prestige of teaching, digitalization cannot be considered as an independent factor that is able to change the professional space so that it becomes more attractive for young professionals.

Keywords: mass digitalization, forced onlineization, digitalization of school education, online education, professional identity, young teachers, Russian megapolis.
Ecology and distribution of desert Truffles in Algeria.
Authors: Fortas Zohra , Dib-Bellahouel Soulef , Chevalier Gérard 
Published: May 2021

Abstract
This first study focuses on geographical distribution of desert truffles in Algeria, their diversity and their ecological requirements during growing seasons according to field surveys carried out during thirty years (1986–2016). Investigations in 61 productive sites of desert truffles spread over several bioclimatic areas revealed the presence of nine species to genera Terfezia, Tirmania and Picoa and their host plants Helianthemum spp. This study complements our earlier work on characterization of Terfezia and Picoa samples harvested throughout Algeria by macro-and micromorphological studies and by molecular phylogeny. Pedoclimatic factors were evaluated, host plants species were identified and mycorrhizal relationships of these fungi species under field conditions were examined. Results revealed that good natural yield desert truffles species is closely linked to intensity and distribution of rainfall, the temperature, frequency of storms during ascomata growing seasons. Nine desert truffles species grow on sandy loam soil and form with annual or perennial Helianthemum spp. endomycorrhizae on calcareous soil and also ectomycorrhizae without mantle on acidic soil in Helianthemum guttatum..
Development and validation of a LRP1B mutation-associated prognostic model for hepatocellular carcinoma
Authors: Xu Jian , Shen Xiaomin , Zhang Bo , Su Rui , Cui Mingxuan , Yan Li , Cao Yu 
Published: May 2021

Abstract
Purpose: To develop a LRP1B gene mutation based prognostic model for hepatocellular carcinoma (HCC) patients risk prediction. Methods: The LRP1B gene mutation rate was calculated from HCC patient samples. Meanwhile, differentially expressed genes according to LRP1B mutant were screened out for prognostic model establishment. Based on this innovative model, HCC patients were categoried into high and low-risk group. The immune status including immune cell infiltration ratio and checkpoints have been explored in two groups. Results: It can be shown here 11 genes demonstrate significant differences according to LRP1B status, which can better predict HCC patient prognosis. The accuracy of the model prediction is evaluated and approved by the AUC value. From the immune cell infiltration ratio analysis, there is a significant difference in the infiltration degree of 7 types of immune cells and 2 immune checkpoints between high and low-risk HCC patients. Meanwhile, LRP1B was tested as a prognostic marker in clinic to predict different stages for HCC with satisfied accurancy. Conclusion: This study has explored a potential prognostic biomarker and developed a novel LRP1B mutation-associated prognostic model for hepatocellular carcinoma, which provides a systematic reference for future better understanding of clinical research.