bluuebunny/crossref_metadata_2025_split huggingface dataset:
Video Dokumenter Informasi Kesenian Sisingaan Pada Dinas Pendidikan dan Kebudayaan Kabupaten Subang
Authors: Sanni M. Ifran , Nurcahya Alifya , Kurniawan Taufiq 
Published: April 2021

In the field of information, audio visual is one of the supporting media in delivering effective information, and is more attractive in its presentation. One of them is sisingaan art from Subang Regency, West Java. Currently, the art of sisingaan requires the design of media in the form of audio-visual because in presenting information on the existing side arts, there is no latest information on the latest side arts. The purpose of this study is to design audio-visual based media so that it can be useful and become an attraction for the community and art craftsmen regarding matters related to the arts of Subang district and increasing the number of sisingaan uses every year. The research methodology carried out during this research is problem analysis method, data collection method, design analysis method and media production concept method which includes preproduction, production and postproduction. After analyzing the above problems, the researchers designed a video for the Sisingaan art information of Subang Regency which is used to provide historical information and a very important lion shape icon. From the design of the art information video, it is hoped that the public will know more about the historical value and the lion symbol icon in the secondary arts of Subang Regency which cannot be removed or replaced with anything.
Extreme Programming Dalam Perancangan Sistem Informasi Jasa Fotografi
Authors: Andriansyah Doni , Nulhakim Lukman 
Published: April 2021

Jasa termasuk kedalam sektor perdagangan yang cukup banyak pelaku usahanya. Tak jarang banyak pelaku usaha yang saling adu strategi untuk memenangkan persaingan bisnis. Salah satunya adalah dengan memanfaatkan teknologi informasi. Website merupakan media yang paling banyak mereka gunakan dalam mempromosikan jasa yang mereka tawarkan. Hal ini tentu saja untuk menjawab permasalahan klasik yang timbul, yaitu pelanggan diharuskan datang langsung ke workshop untuk melakukan pemesanan jasa. Pencatatan transaksi masih dilakukan secara manual sehingga sangat rentan rusak, tercecer, atau bahkan hilang. Tujuan penelitian ini adalah untuk membangun sebuah website yang mampu melayani pemesanan jasa oleh pelanggan dan melakukan pencatatan secara otomatis. Metode yang digunakan dalam pengembangan sistem adalah Extreme Programming yang terdiri dari tahapan perencanaan,perancangan, pengkodean, dan pengujian.
Kata Kunci : extreme programming, jasa, sistem informasi, fotografi
Pemanfaatan Mikrokotroller Untuk Monitoring Suhu Pada Ruangan Server Pada Dinas Komunikasi Dan Informatika Kota Tangerang
Authors: Ilamsyah Ilamsyah , Tamam Iqbal 
Published: April 2021

Untuk mendukung tugas pokok dan memberikan pelayanan terbaik kepada masyarakat dalam bentuk pelayanan komunikasi dan informatika, Dinas Kominfo Kota Tangerang mempunyai sebuah ruangan yang digunakan untuk menyimpan server (aplikasi dan database), Perangkat jaringan (router,hub, dll), Server digunakan dalam rentang waktu yang lama maka kualitas hardware perlu dijaga. Karena sangat pentingnya peran ruangan server, perlu di monitoring secara berkala. Namun permasalahan yang ada pada Dinas Kominfo Kota Tangerang masih menggunakan pengukuran manual serta tidak adanya pencatatan suhu harian pada ruang server dan pada ruangan server hanya mempunyai 3 buah pendingin ruangan (AC) air conditioner, namun belum cukup untuk mencegah terjadinya overheat pada ruangan sever sebab air conditioner digunakan hanya untuk ruangan sedangkan server harus memiliki pendingin yang khusus yang dekat dengan server. Sehingga memerlukan sistem monitoring jarak jauh yang dapat dipantau secara realtime memungkinan dalam pencatatan suhu pada ruangan server. Hasil dari penelitian ini adalah membangun sebuah alat monitoring suhu dengan menggunakan Arduino menggunakan sensor DHT 22 yang berfungsi untuk mengambil data berupa suhu hasil pengukuran dapat tercatat pada website secara real time dan akurat. Alat ini dikembangkan dengan metodeperancangan menggunakan diagram blok loop tertutup dan terbuka serta metode prototype menggunakan metode waterfall.
Kata Kunci : Ruang Server, Monitoring, Arduino Uno
MEDIA PROMOSI ANIMASI MOTION GRAPHIC PADA PT.TIRTA KARYA BUANA
Authors: Ariyanto Kukoh Mey , Zainudin M. N Achmad , Aulia Fajar Alfie 
Published: April 2021

Teknologi wireless Fidelity (Wi-Fi) adalah bagian dari media komunikasi yang digunakan oleh banyak orang, seperti telepon dan TV, dengan teknologi wireless Wireless Local Area Network (WLAN) yang lebih dikenal dengan sebutan Wi-Fi, telah meningkatkan mobilitas pengguna, dan dapat mengatasi keterbatasan teknologi jaringan komputer yang menggunakan media berkabel. PT. Tirta karya Buana adalah penyedia ISP (Internet Service Provider) yang terletak di kota Tangerang dan sekitarnya, untuk mendapatkan layanan berkualitas dan dampaknya terhadap kepuasan masyarakat, maka media promosi diperlukan dengan media utama dalam bentuk animasi.Tujuan dari penelitian ini adalah untuk menginformasikan produk/layanan dan untuk menarik minat orang. Manfaat adalah bahwa calon pelanggan dapat dengan mudah mengetahui informasi yang ada pada PT. Tirta Karya Buana metode penelitiannya adalah: metode wawancara, observasi, konsep produksi media (KPM). Hasil penelitian ini adalah media promosi yang mencakup informasi tentang: harga produk, produk dan jasa, serta lokasi. Animasi ini akan diimplementasikan melalui YouTube dan media sosial. Melalui Motion Graphic media promosi dalam rangka menarik konsumen sehingga dapat meningkatkan jumlah konsumen yang ingin menggunakan jasa internet di PT. Tirta karya Buana.
Kata kunci: Wifi, Animasi, Promosi.
E-LEARNING DALAM PENGEMBANGAN PEMBELAJARAN KRIPTOGRAFI
Authors: Syaifuddin M , Hutagalung Juniar , Ganefri Ganefri 
Published: April 2021

Abstract: Cryptography is an important subject to study because it contains data security. In this course, there are algorithms where each algorithm has a different level of calculation process from one another. Testing has been done several times in the form of training on students and some of them still make mistakes in getting the results of the encryption and decryption process. These errors are caused by a lack of understanding of algorithms and calculations in cryptography. In cryptography, the accuracy of the calculation results is a top priority, because if one does the calculation which is called the encryption and decryption process it will result in an incorrect message/information. To anticipate these errors, this cryptography learning is assisted by a tool called crypTool. This tool is a companion in carrying out the encryption and decryption process to avoid errors in the calculation process. Keywords: Cryptography; E-Learning Abstrak: Kriptografi merupakan salah satu matakuliah yang penting untuk dipelajari, karena didalamnya memuat materi pengamanan data. Dalam matakuliah tersebut terdapat algoritma- algoritma dimana setiap algortima memiliki tingkat proses perhitungan yang berbeda satu dengan yang lainnya. Telah dilakukan beberapa kali pengujian dalam bentuk latihan terhadap mahasiswa dan dari sebagian dari mereka masih melakukan kesalahan dalam mendapatkan hasil proses enkripsi dan dekripsi. Kesalahan tersebut diakibatkan oleh kuranganya memahami algoritma dan perhitungan dalam kriptografi. Dalam kriptografi keakuratan hasil perhitungan menjadi prioritas utama, karena apabila salah dalam melakukan perhitungan yang disebut dengan proses enkripsi dan dekripsi maka akan menghasilkan sebuah pesan/informasi yang salah. Guna mengantisipasi kesalahan tersebut maka pembelajaran kriptografi ini dibantu dengan sebuah tools yang bernama cryptool. Tool ini bersifat pendamping dalam melakukan proses enkripsi dan dekripsi dengan maksud menghindari kesalahan didalam melakukan proses perhitungannya. Kata kunci: E-Learning; Kriptografi
Analisis Pelayanan Badan Administrasi Akademik dan Kemahasiswaan terhadap Kepuasan Mahasiswa STIE Yadika Bangil
Authors: RUMEFI UFI 
Published: April 2021

Penelitian ini dilakukan untuk mengetahui apakah pelayanan BAAK yang meliputi Sub bagian Sarana dan Prasarana (X1), Sub bagian Kemahasiwaan (X2), Sub Bagian Keuangan (X3) dan Sub bagian Akademik (X4) secara parsial maupun secara simultan berpengaruh terhadap kepuasaan mahaiswa (Y), Tujuan dalam penelitian ini adalah untuk mengetahui dan menjelaskan pengaruh Sub bagian Sarana dan Prasarana (X1), Sub bagian Kemahasiwaan (X2), Sub Bagian Keuangan (X3) dan Sub bagian Akademik (X4) secara parsial maupun secara simultan terhadap kepuasaan mahaiswa (Y) sample dalam penelitian ini adalah mahasiswa yang mempunyai frekuensi tingkat kunjungan pada BAAK lebih dari 12 kali dalam satu bulan. hasil penelitian didapatkan adjusted R skuare sebesar .815 hal ini berarti 81,5% variabel bebas mempengaruhi variabel terikat, Variabel X2 sampai dengan variabel X4 mempengaruhi variabel Y dengan nilai sig < 0,05 sedangkan variabel X1 tidak mempengaruhi variabel Y dengan nilai sig > 0,05.
Capturing Herder: a three-step approach to the identification of language ideologies using corpus linguistics and critical discourse analysis
Authors: Ajšić Adnan 
Published: April 2021

Recent lexical approaches to the identification of language ideologies focus on the application of quantitative corpus-linguistic techniques to large data sets as a way to minimise researcher inference and ensure more objective sampling methods, replicability of analytical procedures, and a higher degree of generalisability ( Fitzsimmons-Doolan, 2014 ; Subtirelu, 2015 ; Vessey, 2017 ; Wright and Brooks, 2019 ; and McEntee-Atalianis and Vessey, 2020 ). Based on two comprehensive, specialised research (11.6 million words) and comparator (22.4 million words) newspaper corpora, this study offers an examination of the effectiveness of the multivariate and univariate statistical techniques, and proposes a three-step approach whereby corpus linguistics and critical discourse analysis are combined to identify ( 1) thematic and ( 2) ideological discourses (cf. ‘d’/’D’ discourses; Gee, 2010 ), and ( 3) language ideologies. In contrast to recent contributions, it is argued that item frequency is not necessarily a reliable or effective indicator of language ideologies but, rather, of language-related discourses which can be examined for implicit and explicit language-ideological content. A combination of multivariate and univariate statistical techniques, and the three-step approach are shown to be a highly effective methodological solution for synchronic and diachronic language ideology and discourse research based on topically/discursively heterogeneous corpora.
Bilirubin Induces Pain Desensitization in Cholestasis by Activating 5-Hydroxytryptamine 3A Receptor in Spinal Cord
Authors: Kong Erliang , Wang Hongqian , Wang Xiaoqiang , Zhang Yan , Zhang Jinmin , Yu Weifeng , Feng Xudong , Sun Yuming , Wu Feixiang 
Published: April 2021

BackgroundCholestasis patients often suffer from pain desensitization, resulting in serious complications in perioperative period. This study was aim to investigate the mechanism of bilirubin in cholestasis mediating pain desensitization through 5-hydroxytryptamine 3A (5-HT3A) receptor activation in spinal dorsal horn (SDH).MethodsA cholestasis model was established by bile duct ligation (BDL) in rats. Pain thresholds of rats were measured after BDL or intrathecally injecting bilirubin in the presence or absence of agonist (mCPBG) and antagonists (ondansetron, bicuculline, or CGP55845). Expression of 5-HT3 receptors, and the affinity and binding mode of bilirubin to 5-HT3A receptor were determined. Effects of bilirubin on γ-aminobutyric acid (GABA) pathway and the interactions with 5-HT3A receptor were tested.ResultsBilirubin was elevated significantly in both serum and CSF in BDL rats, accompanied with the up-regulation of pain thresholds. Both of 5-HT3A receptor and GABAA receptor antagonists could reverse the increased pain threshold in BDL rats. Further, 5-HT3A and GABAA receptor expressions were increased in BDL rats or intervention with bilirubin. Molecular docking suggested that bilirubin entered the hydrophobic pocket pre-formed in 5-HT3A receptor with potential hydrogen bonding. Bilirubin also increased GABA concentrations in CSF and GABAergic spontaneous inhibitory postsynaptic current in spinal cord, and directly induced inward currents in HEK293 cells which were overexpressed 5-HT3A receptor by lentivirus.ConclusionIn conclusion, bilirubin induced pain desensitization in cholestasis by activating 5-HT3A receptor in spinal cord. The activation of 5-HT3A receptor might regulate pain threshold by acting on the GABA pathway.
Aerobic Versus Resistance Training Effects on Ventricular-Arterial Coupling and Vascular Function in the STRRIDE-AT/RT Trial
Authors: Lekavich Carolyn L. , Allen Jason D. , Bensimhon Daniel R. , Bateman Lori A. , Slentz Cris A. , Samsa Gregory P. , Kenjale Aarti A. , Duscha Brian D. , Douglas Pamela S. , Kraus William E. 
Published: April 2021

Background: The goal was studying the differential effects of aerobic training (AT) vs. resistance training (RT) on cardiac and peripheral arterial capacity on cardiopulmonary (CP) and peripheral vascular (PV) function in sedentary and obese adults.Methods: In a prospective randomized controlled trial, we studied the effects of 6 months of AT vs. RT in 21 subjects. Testing included cardiac and vascular ultrasoundography and serial CP for ventricular-arterial coupling (Ees/Ea), strain-based variables, brachial artery flow-mediated dilation (BAFMD), and peak VO2 (pVO2; mL/kg/min) and peak O2-pulse (O2p; mL/beat).Results: Within the AT group (n = 11), there were significant increases in rVO2 of 4.2 mL/kg/min (SD 0.93) (p = 0.001); O2p of 1.9 mL/beat (SD 1.3) (p = 0.008) and the brachial artery post-hyperemia peak diameter 0.18 mm (SD 0.08) (p = 0.05). Within the RT group (n = 10) there was a significant increase in left ventricular end diastolic volume 7.0 mL (SD 9.8; p = 0.05) and percent flow-mediated dilation (1.8%) (SD 0.47) (p = 0.004). Comparing the AT and RT groups, post exercise, rVO2 2.97, (SD 1.22), (p = 0.03), O2p 0.01 (SD 1.3), (p = 0.01), peak hyperemic blood flow volume (1.77 mL) (SD 140.69) (p = 0.009), were higher in AT, but LVEDP 115 mL (SD 7.0) (p = 0.05) and Ees/Ea 0.68 mmHg/ml (SD 0.60) p = 0.03 were higher in RT.Discussion: The differential effects of AT and RT in this hypothesis generating study have important implications for exercise modality and clinical endpoints.
Everolimus Related Fulminant Hepatitis in Pancreatic Neuroendocrine Tumor With Liver Metastases: A Case Report and Literature Review
Authors: Chang Shih-Chun , Tsai Chun-Yi , Liu Keng-Hao , Wang Shang-yu , Hsu Jun-Te , Yeh Ta-Sen , Yeh Chun-Nan 
Published: April 2021

BackgroundEverolimus, an immunosuppressant, is approved for the treatment of advanced renal cell carcinoma, metastatic hormone receptor-positive breast cancer, and pancreatic neuroendocrine tumors (P-NETs) but has been reported to be related to hepatitis B reactivation. Here, we present the first case of fatal fulminant hepatitis B reactivation in a man with P-NET accompanied by multiple liver metastases who received everolimus and octreotide long-acting repeatable (LAR).Case PresentationA 45-year-old male had a history of chronic hepatitis B infection. He was found to have a complicated liver cyst incidentally, and then he underwent biopsy, which disclosed a grade 2 neuroendocrine tumor (NET). Subsequent MRI of the abdomen and PET revealed a solid mass at the pancreatic tail with numerous liver tumors favoring metastases and peripancreatic lymph node metastases. Transarterial chemoembolization (TACE) of the right lobe of the liver was performed, and he started to take 5 mg everolimus twice a day and 20 mg octreotide LAR every month 8 days after the 1st TACE. No hepatitis B virus (HBV) prophylaxis treatment was administered. He then underwent laparoscopic distal pancreatectomy and splenectomy three and half months after the initial treatment of everolimus. He continued everolimus 5 mg twice a day and octreotide 20 mg every month after the operation. Three months later, hepatic failure occurred due to acute hepatitis B flare-up–related fulminant hepatic failure since other possible causes of hepatic failure were excluded. Five days after hepatic failure presented, hepatic failure was apparent, and pulseless ventricular tachycardia occurred. The patient expired after failed resuscitation.ConclusionA literature review of everolimus-related hepatitis B reactivation was conducted. In P-NET patients with chronic hepatitis B who will undergo everolimus treatment, HBV prophylaxis should be considered since fatal hepatitis B reactivation might occur under rare conditions.
The Impact of COVID-19 Pandemic Lockdown on the Incidence of New-Onset Type 1 Diabetes and Ketoacidosis Among Saudi Children
Authors: Alaqeel Aqeel , Aljuraibah Fahad , Alsuhaibani Mohammed , Huneif Mohammed , Alsaheel Abdulhameed , Dubayee Mohammad Al , Alsaedi Abdulaziz , Bakkar Ayman , Alnahari Ahmed , Taha Areej , Alharbi Khulood , Alanazi Yousef , Almadhi Samia , Khalifah Reem Al 
Published: April 2021

BackgroundOverburdened healthcare systems during the coronavirus disease (COVID-19) pandemic led to suboptimal chronic disease management, including that of pediatric type 1 diabetes mellitus (T1DM). The pandemic also caused delayed detection of new-onset diabetes in children; this increased the risk and severity of diabetic ketoacidosis (DKA). We therefore investigated the frequency of new-onset pediatric T1DM and DKA in Saudi Arabia during the COVID-19 pandemic and compared it to the same period in 2019.MethodsWe conducted a multicenter retrospective cohort study, including patients aged 1–14 years admitted with new-onset T1DM or DKA during the COVID-19 pandemic (March–June 2020) and the same period in 2019. We assessed factors including age, sex, anthropometric measures, nationality, duration of diabetes, diabetes management, HbA1c levels, glycemic control, cause of admission, blood gas levels, etiology of DKA, DKA complications, length of hospital stay, and COVID-19 test status.ResultDuring the lockdown, 106 children, compared with 154 in 2019, were admitted to 6 pediatric diabetes centers. Among the admissions, DKA was higher in 2020 than in 2019 (83% vs. 73%; P=0.05; risk ratio=1.15; 95% confidence interval, 1.04–1.26), after adjusting for age and sex. DKA frequency among new-onset T1DM and HbA1c levels at diagnosis were higher in 2020 than in 2019 (26% vs. 13.4% [P=&lt;0.001] and 12.1 ± 0.2 vs. 10.8 ± 0.25 [P&lt;0.001], respectively). Females and older patients had a higher risk of DKA.ConclusionThe lockdown implemented in Saudi Arabia has significantly impacted children with T1DM and led to an increased DKA frequency, including children with new-onset T1DM, potentially owing to delayed presentation.
Untargeted Metabolomic Profiling of the Correlation Between Prognosis Differences and PD-1 Expression in Sepsis: A Preliminary Study
Authors: Bu Y. , Wang H. , Ma X. , Han C. , Jia X. , Zhang J. , Liu Y. , Peng Y. , Yang M. , Yu K. , Wang C. 
Published: April 2021

Objectives: The mortality rate of sepsis remains very high. Metabolomic techniques are playing increasingly important roles in diagnosis and treatment in critical care medicine. The purpose of our research was to use untargeted metabolomics to identify and analyze the common differential metabolites among patients with sepsis with differences in their 7-day prognosis and blood PD-1 expression and analyze their correlations with environmental factors.Methods: Plasma samples from 18 patients with sepsis were analyzed by untargeted LC-MS metabolomics. Based on the 7-day prognoses of the sepsis patients or their levels of PD-1 expression on the surface of CD4+ T cells in the blood, we divided the patients into two groups. We used a combination of multidimensional and monodimensional methods for statistical analysis. At the same time, the Spearman correlation analysis method was used to analyze the correlation between the differential metabolites and inflammatory factors.Results: In the positive and negative ionization modes, 16 and 8 differential metabolites were obtained between the 7-day death and survival groups, respectively; 5 and 8 differential metabolites were obtained between the high PD-1 and low PD-1 groups, respectively. We identified three common differential metabolites from the two groups, namely, PC (P-18:0/14:0), 2-ethyl-2-hydroxybutyric acid and glyceraldehyde. Then, we analyzed the correlations between environmental factors and the common differences in metabolites. Among the identified metabolites, 2-ethyl-2-hydroxybutyric acid was positively correlated with the levels of IL-2 and lactic acid (Lac) (P &lt; 0.01 and P &lt; 0.05, respectively).Conclusions: These three metabolites were identified as common differential metabolites between the 7-day prognosis groups and the PD-1 expression level groups of sepsis patients. They may be involved in regulating the expression of PD-1 on the surface of CD4+ T cells through the action of related environmental factors such as IL-2 or Lac, which in turn affects the 7-day prognosis of sepsis patients.
Non-invasive Urinary Biomarkers in Moyamoya Disease
Authors: Sesen Julie , Driscoll Jessica , Moses-Gardner Alexander , Orbach Darren B. , Zurakowski David , Smith Edward R. 
Published: April 2021

Introduction:A major difficulty in treating moyamoya disease is the lack of effective methods to detect novel or progressive disease prior to the onset of disabling stroke. More importantly, a tool to better stratify operative candidates and quantify response to therapy could substantively complement existing methods. Here, we present proof-of-principle data supporting the use of urinary biomarkers as diagnostic adjuncts in pediatric moyamoya patients.Methods:Urine and cerebrospinal fluid specimens were collected from pediatric patients with moyamoya disease and a cohort of age and sex-matched control patients. Clinical and radiographic data were paired with measurements of a previously validated panel of angiogenic proteins quantified by ELISA. Results were compared to age and sex-matched controls and subjected to statistical analyses.Results:Evaluation of a specific panel of urinary and cerebrospinal fluid biomarkers by ELISA demonstrated significant elevations of angiogenic proteins in samples from moyamoya patients compared to matched controls. ROC curves for individual urinary biomarkers, including MMP-2, MMP-9, MMP-9/NGAL, and VEGF, showed excellent discrimination. The optimal urinary biomarker was MMP-2, providing a sensitivity of 88%, specificity of 100%, and overall accuracy of 91%. Biomarker levels changed in response to therapy and correlated with radiographic evidence of revascularization.Conclusions:We report, for the first time, identification of a panel of urinary biomarkers that predicts the presence of moyamoya disease. These biomarkers correlate with presence of disease and can be tracked from the central nervous system to urine. These data support the hypothesis that urinary proteins are useful predictors of the presence of moyamoya disease and may provide a basis for a novel, non-invasive method to identify new disease and monitor known patients following treatment.