bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surgical management of an extensive spinal epidural abscess: illustrative cases
Authors: Eroshkin Aleksey , Romanukha Dmytro , Voitsekhovskyi Serhiy 
Published: January 2021

BACKGROUNDExtensive spinal epidural abscesses (SEAs) occupying three or more spinal regions are rare. This study aimed to address the key dilemma of surgical treatment for holospinal epidural abscesses, i.e., to determine the required scope of surgery and minimize surgical trauma with adequate purulent drainage.OBSERVATIONSTwo patients with extensive SEAs were treated at the Neurosurgery Department of the Central Hospital of Ministry of Internal Affairs of Ukraine from 2018 to 2020. Both patients had a neurological deficit and general inflammatory response syndrome. Spinal magnetic resonance examinations were performed, showing that the first and second patients had extensive SEAs at T11/S1 and C2/L1, respectively. Both underwent minimally invasive abscess drainage via intra- and translaminar access at the most caudal point using an epidural silicone catheter in the cranial direction along the entire length of the abscess.LESSONSTo achieve the key goal of extensive SEA treatment, i.e., to prevent the development of a persistent neurological deficit, immediate effective spinal canal decompression should be performed. Access method and scope should meet the requirements of spinal canal decompression and purulent content aspiration to the greatest possible extent while inducing minimal trauma.
[68Ga]-DOTATATE PET/CT and PET/MRI in the diagnosis and management of esthesioneuroblastoma: illustrative cases
Authors: Roytman Michelle , Tassler Andrew B. , Kacker Ashutosh , Schwartz Theodore H. , Dobri Georgiana A. , Strauss Sara B. , Capalbo Alyssa M. , Magge Rajiv S. , Barbaro Marissa , Lin Eaton , Osborne Joseph R. , Jana Ivanidze  
Published: January 2021

BACKGROUNDEsthesioneuroblastoma (ENB), also known as olfactory neuroblastoma, is a rare sinonasal neuroectodermal malignancy with a slow onset of symptoms, favorable 5-year survival, and a propensity for delayed locoregional recurrence. Current treatment options include resection, adjuvant radiotherapy, and/or chemotherapy; however, because of its rarity and location, determining the optimal treatment for ENB has been challenging.OBSERVATIONSENBs strongly express somatostatin receptors (SSTRs), particularly SSTR2, providing a molecular target for imaging and therapy.LESSONsThe authors present a case series of ENBs imaged with [68Ga]-DOTATATE PET/MRI and PET/CT and discuss the emerging role of [68Ga]-DOTATATE PET for ENB diagnosis, staging, and treatment response monitoring.
Endovascular treatment of a ruptured posterior fossa pure arterial malformation: illustrative case
Authors: Chua Melissa M. J. , Gupta Saksham , Essayed Walid Ibn , Donnelly Dustin J. , Ziayee Habibullah , Vicenty-Padilla Juan , Das Alvin S. , Lai Rosalind P. M. , Izzy Saef , Aziz-Sultan Mohammad Ali 
Published: January 2021

BACKGROUNDPure arterial malformations (PAMs) are rare vascular anomalies that are commonly mistaken for other vascular malformations. Because of their purported benign natural history, PAMs are often conservatively managed. The authors report the case of a ruptured PAM leading to subarachnoid hemorrhage (SAH) with intraventricular extension that was treated endovascularly.OBSERVATIONSA 38-year-old man presented with a 1-day history of headaches and nausea. A computed tomography scan demonstrated diffuse SAH with intraventricular extension, and angiography revealed a right posterior inferior cerebellar artery–associated PAM. The PAM was treated with endovascular Onyx embolization.LESSONSTo the authors’ knowledge, only 2 other cases of SAH associated with PAM have been reported. In those 2 cases, surgical clipping was pursued for definitive treatment. Here, the authors report the first case of a ruptured PAM treated using an endovascular approach, showing its feasibility as a treatment option particularly in patients in whom open surgery is too high a risk.
Analisis Kualitatif Kandungan Fenolik dalam Fraksi Etil Asetat dan Fraksi Metanol dari Ekstrak Kulit Jagung (Zea mays L.)
Authors: Suputri Yuniarthi Dwi , Ananto Agus Dwi , Andayani Yayuk 
Published: January 2021

ABSTRAKProduksi tanaman jagung yang semakin meningkat menyebabkan peningkatan limbah kulit jagung semakin tinggi. Kulit jagung dapat dimanfaatkan dalam bidang kesehatan dan berpotensi sebagai antioksidan. Kulit jagung mengandung senyawa fenolik dan flavonoid yang dapat bertindak sebagai antioksidan. Tujuan dari penelitian ini adalah untuk mengetahui kandungan senyawa pada fenolikfraksi etil asetat dan fraksi metanol kulit jagung. Ekstraksi kulit jagung dilakukan dengan metode maserasi menggunakan pelarut etanol 96%. Fraksinasi ekstrak etanol kulit jagung dilakukan dengan fraksinasi bertingkat menggunakan pelarut metanol dan etil asetat. Kedua fraksi yang diperoleh kemudian dianalisis secara kualitatif dengan metode Kromatografi Lapis Tipis. Fase diam yang digunakan adalah plat silica gel G60F254 dan fase gerak yang digunakan adalah kombinasi eluen kloroform: etil asetat: n-butanol: asam format (5:2:2:1). Hasil pemisahan ditandai dengan munculnya noda bercak saat diamati dengan sinar UV 254 nm dan 366 nm. Nilai Rf bercak yang muncul kemudian dihitung lalu dibandingkan dengan nilai Rf literatur untuk mengidentifikasikan senyawa yang terpisah. Hasil analisis kualitatif fraksi etil asetat dan fraksi metanol kulit jagung menunjukkan keberadaan senyawa fenolik. Hasil ini ditunjukkan dengan munculnya noda bercak dengan nilai Rf 0,75 yang memiliki kemiripan dengan nilai Rf asam galat (0,76). Kata kunci : Kulit jagung; Kromatografi lapis tipis; Analisis kualitatif. ABSTRACTCorn production keeps increasing causing increasing in corn husk waste. Cornhusk can be used in medical field and have potential as an antioxidant. Cornhusk contains phenol and flavonoid metabolites that can act as antioxidants. The aim of this study is to determine the presence of phenol metabolites in ethyl acetate and methanol fraction of cornhusk. Cornhusk extraction was carried out by a maceration method using ethanol 96%. Fractionation of ethanolic cornhusk extract was carried out by liquid-liquid extraction using a separating funnel with methanol and ethyl acetate solvent. The two fractions then analyzed qualitative by Thin Layer Chromatography. The stationary phase used is silica gel G60F254. The mobile phase used is a combination of chloroform: ethyl acetate: n-butanol: formic acid (5:2:2:1). The separation result marked by the presence of stains when observed by UV 254 nm and 366 nm light. The Rf value then measured and compared to Rf value in the literature to determine the separated substance. The qualitative analysis result of corn husk ethyl acetate fraction and methanol fraction indicated the presence of phenolic metabolites. This result is showed by the presence of stain with Rf value 0,75 that has similarity with Rf value of gallic acid (0,76). Keywords : Cornhusk; Thin layer chromatography; Qualitative analysis.
Kepatuhan Ibu Hamil Dalam Mengkonsumsi Tablet Fe (Ferrum) Terhadap Kejadian Anemia Di Desa Langgenharjo Kecamatan Juwana
Authors: Pratiwi Yulia , Safitri Tya 
Published: January 2021

ABSTRAKSelama kehamilan, tubuh wanita memerlukan lebih banyak darah untuk mendukung pertumbuhan bayi. Wanita hamil berisiko tinggi mengalami anemia defisiensi besi. Wanita hamil membutuhkan zat besi tambahan untuk memasok oksigen ke bayi. Untuk itulah wanita hamil perlu mengkonsumsi Fe untuk mensuplai kebutuhan darah. Kepatuhan dalam konsumsi tablet Fe merupakan hal yang perlu diperhatikan. Tujuan penelitian ini adalah untuk mengetahui bagaimana pengaruh kepatuhan ibu hamil dalam konsumsi tablet Fe terhadap tingkat kejadian anemia di Desa Langgenharjo, Kecamatan Juwana. Penelitian ini menggunakan jenis rancangan observasional analitik dengan pendekatan cross sectional, observasi atau pengumpulan data, serta pemberian edukasi di Desa Langgenharjo. Metode yang digunakan dalam penelitian adalah metode kuantitatif yang bersifat deskriptif non eksperimental. Instrumen penelitian yang digunakan dalam peneltian ini berupa kuesioner dan edukasi. Data dianalisis dengan SPSS 22,0 dengan menggunakan uji normalitas, uji Chi-Square. Hasil penelitian menunjukan bahwa tidak terdapat hubungan antara kepatuhan ibu hamil dalam mengkonsumsi tablet Fe terhadap tingkat kejadian anemia dengan p (value) 0,229.Kata kunci : Kepatuhan; Ibu hamil; Konsumsi; Tablet Fe.ABSTRACTDuring pregnancy, a woman's body needs more blood to support the baby's growth. Pregnant women are at high risk for iron deficiency anemia. Pregnant women need extra iron to supply oxygen to the baby. For communication, pregnant women need to take iron to supply blood. Compliance with the consumption of Fe tablets is something that needs attention. The purpose of this study was to see how compliance of pregnant women in consuming Fe tablets on the incidence of anemia in Langgenharjo Village, Juwana District. This research used an analytic observational design with a cross sectional approach, observation or data, as well as providing education in Langgenharjo Village. The method used in this research is quantitative quantitative which is descriptive non-experimental. The research instruments used in this research were questionnaires and education. Data were analyzed using SPSS 22.0 using normality test, Chi-Square test. The results showed that there was no effect between pregnant women in consuming Fe tablets on the incidence rate of anemia with p (value) 0.229.Keywords : Compliance; Pregnant women; Consumption; Fe Tablet.
Faktor yang Berhubungan dengan Perilaku Pencegahan HIV/AIDS pada Kelompok LSL di Kota Palu
Authors: Septiani  
Published: January 2021

LSL adalah singkatan yang menggambarkan Laki-laki berhubungan Seks dengan Laki-laki. LSL adalah salah satu kelompok berisiko tinggi penularan HIV/AIDS, karena perilaku seksual mereka adalah anal dan seks oral. Berdasarkan data dari Dinas Kesehatan Kota Palu pada tahun 2019 bahwa 94 kasus HIV terjadi pada LSL. Tujuan dari penelitian ini adalah untuk mengetahui faktor yang berhubungan dengan perilaku pencegahan HIV/AIDS pada kelompok LSL di Kota Palu. Jenis penelitian adalah kuantitatif dengan pendekatan cross sectional. Populasi berjumlah 284 orang, setelah menggunakan rumus slovin didapatkan sampel sebanyak 74 orang yang diambil melalui teknik snawball sampling. Analisis data menggunakan univariat dan bivariat menggunakan uji chi-square dengan nilai α<0,05. Hasil penelitian menunjukkan beberapa variabel yaitu: pengetahuan (p= 0,037), sikap (p= 0,005), dan dukungan petugas kesehatan (p = 0,000) berhubungan dengan perilaku pencegahan HIV/AIDS pada kelompok LSL di Kota Palu. Kesimpulan: Ada hubungan antara pengetahuan, sikap, dukungan petugas kesehatan dengan perilaku pencegahan HIV/AIDS pada kelompok LSL di Kota Palu, disarankan kepada LSL untuk meningkatkan perilaku pencegahan dengan menggunakan kondom secara konsisten dan memanfaatkan layanan konseling dan tes HIV, dan petugas kesehatan dapat memberikan bantuan perawatan dan konseling tanpa stigma dan diskriminasi.
Role of the Kazakhstan-German Cooperation in Improving Scientific Tools for Evaluation of Vocational Education Programs
Authors: Karstina S. G. , Zechiel O. N. , Machado C. 
Published: January 2021

The work carried out within the framework of the German-Kazakh project “GeKaVoс – Transfer of dual training in logistics, mechatronics and sustainable energy supply to Kazakhstan” can be considered as one of the crucial aspects of the contribution to improving the quality of system of technical and vocational education (TVET), the achievement of high rates of employment of graduates of the TVET system, improve the ratio of supply and demand in the labor market.As the analysis of the TVET system in Kazakhstan presented in the article shows, different forms of cooperation between participants of the educational process in the country (corporate partnership, industrial clusters, patronage of large and medium-sized enterprises over educational institutions, etc.) contribute to the development of a market-oriented education system. Monitoring and evaluation of the effectiveness of technical and vocational education, as well as identifying opportunities to improve its quality and scope require understanding of its nature, its functions, goals and key characteristics, the application of effective scientific tools to assess vocational technical education and training of trainers (tutors) (TVET).The paper shows that the success of the transfer of educational programs depends primarily on the willingness to work together of all the stakeholders, the creation of systematic structures of interaction in the development of educational programs of different levels, improving methods of forecasting demand not only for certain professions, but also for professional and pre-professional competencies. The purpose of scientific evaluation of the dual system and workplace training is to prove its effectiveness as an educational strategy that provides students with real work experience, where they can apply social and technical skills and develop them.
Online Courses: To Accept Impossible to Ignore
Authors: Lobova S. V. , Ponkina E. V. 
Published: January 2021

Online courses are changing the landscape of higher education. However, their adoption by the teaching community of Russian universities has not yet been fully studied. The conducted sociological research made it possible to assess the involvement of Russian university lecturers in the processes of digitalization of education, to determine the motives for their activities in creating and integrating online courses into the educational process, and to form an understanding of the acceptance of online learning by the Russian teaching community. The pyramid of acceptance of Cox and Trotter’s open educational resources is a repulsive idea for the study. The empirical basis of the study was the responses and opinions of teachers of Russian universities, representing different categories of universities.The results of the research can be of practical significance in determining the directions of social policy of education digitalization at the state level in terms of developing stimulating and motivating measures and measures to support and provide the necessary guarantees to lecturers, especially regional ones, during the transformation period.
Existence and asymptotic behavior of solutions for a class of semilinear subcritical elliptic systems
Authors: Arruda Suellen Cristina Q. , Figueiredo Giovany M. , Nascimento Rubia G. 
Published: January 2021

In this paper we study the asymptotic behaviour of a family of elliptic systems, as far as the existence of solutions is concerned. We give a special attention to the asymptotic behaviour of W and V as ε goes to zero in the system [Formula: see text] where [Formula: see text], W and V are positive potentials of [Formula: see text] class and Q is a p-homogeneous function with subcritical growth. We establish the existence of a positive solution by considering two classes of potentials W and V. Our arguments are based on penalization techniques, variational methods and the Moser iteration scheme.
Comparison of Long-term Ambulatory Function in Patients with Duchenne Muscular Dystrophy Treated with Eteplirsen and Matched Natural History Controls
Authors: Mendell Jerry R. , Khan Navid , Sha Nanshi , Eliopoulos Helen , McDonald Craig M. , Goemans Nathalie , Mercuri Eugenio , Lowes Linda P. , Alfano Lindsay N. ,   on behalf of the Eteplirsen Study Group
Published: January 2021

Background: Duchenne muscular dystrophy (DMD) is a rare, X-linked, fatal, degenerative neuromuscular disease caused by DMD gene mutations. A relationship between exon skipping and dystrophin production in exon 51-amenable patients treated with eteplirsen (EXONDYS 51®) is established. Once-weekly eteplirsen significantly increased dystrophin, with slower decline in ambulatory function compared to baseline. Long-term treatment with eteplirsen leads to accumulation of dystrophin over time and observed functional benefits in patients with DMD. Objective: Compare long-term ambulatory function in eteplirsen-treated patients versus controls. Methods: Study 201/202 included 12 eteplirsen-treated patients assessed twice/year for ambulatory function over 4 years. Ambulatory evaluations (6-minute walk test [6MWT], loss of ambulation, and North Star Ambulatory Assessment [NSAA]) were compared with matched controls from Italian Telethon and Leuven registries. Results: At Years 3 and 4, eteplirsen-treated patients demonstrated markedly greater mean 6MWT than controls (difference in change from baseline of 132 m [95%CI (29, 235), p = 0.015] at Year 3 and 159 m [95%CI (66, 253), p = 0.002] at Year 4). At Year 4, a significantly greater proportion of eteplirsen-treated patients were still ambulant versus controls (10/12 vs 3/11; p = 0.020). At Year 3, eteplirsen-treated patients demonstrated milder NSAA decline versus controls (difference in change from baseline of 2.6, 95%CI [-6, 11]), however, the difference was not statistically significant; Year 4 control NSAA data were not available. Conclusion: In this retrospective matched control study, eteplirsen treatment resulted in attenuation of ambulatory decline over a 4-year observation period, supporting long-term benefit in patients with DMD.
Myocardial performance index in term appropriate and small for gestational age neonates - a cross sectional study
Authors: Vats K. , Choudhary S.K. , Kumar D. , Maria A. , Bandopadhyay T. 
Published: January 2021

BACKGROUND: It is known that small for gestational age (SGA) babies may be at an increased risk of cardiovascular diseases during adulthood. There is paucity of literature regarding comparative cardiac functions of SGA and appropriate for gestational age (AGA) babies in neonatal period. The present study was conceived to compare the cardiac function of term small and appropriate for gestational age (AGA) babies through a relatively novel echocardiographic index in early neonatal period. OBJECTIVES: To compare values of myocardial performance index (MPI) index (MPI = IVCT + IVRT/ET) at 48–72 hours of age among AGA and SGA babies. METHODS: Morphological and anthropometric assessment of serially born term babies was done at time of birth to recruit hundred each of AGA and SGA babies. Tissue Doppler Imaging (TDI) was done between 48–72 hours for each enrolled baby to assess both right and left ventricle MPI in each group. RESULTS: Mean±SD values for right ventricular MPI in AGA and SGA groups were 0.268 + 0.007 and 0.30 + 0.026 respectively ( p < 0.001). Mean±SD values for left ventricular MPI in AGA and SGA groups were 0.25 + 0.012 and 0.30 + 0.017 respectively ( p < 0.001). There was significant negative correlation between MPI values for either ventricles and the birth weight (spearmen’s rho of –0.66) ( p < 0.001). Mean±SD values for LVET in AGA and SGA group were 0.304 + 0.026 and 0.266 + 0.032 respectively ( p < 0.001). CONCLUSION: MPI had a higher absolute value in the SGA babies as compared to AGA babies. These observations point towards suboptimal cardiac performance among SGA babies as compared to AGA babies on the basis of myocardial performance index.
KISAH NABI NUH DALAM AL-QUR’AN (Pendekatan Intertekstual Julia Kristeva)
Authors: Khikmatiar Azkiya 
Published: January 2021

This article discusses the story of Noah in the Qur'an. As a story contained in the Qur'an and the Bible, the story of Noah is very important to find the the differences between them. Therefore, the used approach is intertextuality initiated by Julia Kristeva who tried to compare two narrations. By using this approach , we found many differences. In the structure of narration, al-Qur’an does many simplifications, so that the haplological principle becomes dominant in each fragment. However, in other fragments other principles are also found such as existence, modification, and conversion. The most basic difference between them is in theme of the story. The story of Noah in the Qur'an has monotheism or tauhid theme, while in the Bible the theme is human crime.
ДЕФЕКТИ КУЛЬТУРИ СПІЛКУВАННЯ МАЙБУТНІХ ПЕДАГОГІВ І ШЛЯХИ ЇХ ПОДОЛАННЯ
Authors: Ковальова О.В. , Гавриш О. Г. , Кудрявцева В. В. 
Published: January 2021

У статті висвітлюється проблема неефективної культури спілкування майбутніх педагогів, бар’єри в спілкуванні та способи їх подолання. Автори підкреслюють, що майбутнім викладачам необхідно оволодіти майстерністю спілкування, щоб інформація для студентів була зрозумілою та якісною. Розрізняють вербальні і невербальні засоби спілкування. Серед невербальних засобів важливими є жести, особливості ходи, голосу, міміка, мікроміміка, поза, пантоміміка та дистанція.
У статті також зазначено, що відсутність культури спілкування породжує чимало дефектів у комунікації, яка порушує всі норми та правила мовленнєвого етикету. У даному дослідженні зауважено, що моральна культура спілкування, зокрема, включає: знання культурних моделей поведінки і уміння їх адекватно використовувати в кожній конкретній ситуації спілкування. Відсутність культури спілкування свідчить про бездуховність людини.
Автори виділяють декілька видів дефектних рівнів спілкування: моральний вакуум, відсутність моральної ініціативи, моральний камуфляж, моральний примітивізм, моральна нетерпимість.
У статті зазначено також, що бар’єри у спілкуванні у широку сенсі поділяються на внутрішні та зовнішні, але деякі науковці дають більш детальну класифікацію. Вони виділяють наступні типи бар’єрів: комунікативний, психологічний, інтелектуальний, бар’єри культурних упереджень, естетичний, мотиваційний, емоційний тощо.
Крім цього, автори надають рекомендації щодо подолання бар’єрів та дефектів спілкування, наприклад, навчитися застосовувати гумор у певних ситуаціях, постійно вдосконалюватися, навчитися уникати конфліктів, підвищувати рівень стресостійкості, навчитися коректно робити зауваження, слідкувати за своєю мовою тощо.
МЕТОДИЧНІ ЗАСАДИ ХОРМЕЙСТЕРСЬКОЇ ПІДГОТОВКИ МАЙБУТНІХ УЧИТЕЛІВ МУЗИЧНОГО МИСТЕЦТВА
Authors: Софроній З. В , Чурікова-Кушнір О. Д. 
Published: January 2021

У статті актуалізовано методичні засади хормейстерської підготовки майбутніх учителів музичного мистецтва. Проаналізовано здобутки вітчизняної диригентсько-хорової освіти та їх значення у формуванні сучасних методологічних орієнтирів і закономірностей організації процесу хормейстерської підготовки здобувачів вищої освіти. Обґрунтовано сутність, зміст і структуру хормейстерської підготовки майбутніх учителів музичного мистецтва у закладах вищої освіти.
Розглянуто зміст хормейстерської підготовки, можемо трактувати її як цілісний навчально-творчий процес, який охоплює усі види хормейстерської діяльності, починаючи з вибору хорового твору, його розучування, вивчення й закінчуючи виконанням у процесі концертного виступу. Зміст репетиційної роботи розглядається як взаємозв'язок хормейстера та творчого колективу, що відображає єдність хорового виконавства і технологічні особливості роботи з хором.
Визначено, що інтеграція різних видів диригентсько-хорової діяльності у процесі навчання дозволяє сформувати у здобувачів вищої освіти цілий комплекс фахових компетентностей (хормейстерських знань, умінь і навичок), досвід диригентсько-хорової діяльності й емоційно-творчого ставлення до роботи з хоровим колективом.
Доведено, що ефективність хормейстерської підготовки майбутніх учителів музичного мистецтва забезпечує методична система, основою якої є впровадження у теорію й практику вищої освіти національних та регіональних культурно-мистецьких цінностей, творчих досягнень і диригентсько-хорового досвіду видатних діячів хорового мистецтва, інноваційних технологій і сучасних засобів навчання.