bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uncovering Modern Clinical Applications of Fuzi and Fuzi-Based Formulas: A Nationwide Descriptive Study With Market Basket Analysis
Authors: Tai Chi-Jung , El-Shazly Mohamed , Tsai Yi-Hong , Csupor Dezső , Hohmann Judit , Wu Yang-Chang , Tseng Tzyy-Guey , Chang Fang-Rong , Wang Hui-Chun 
Published: April 2021

Background: As time evolved, traditional Chinese medicine (TCM) became integrated into the global medical system as complementary treatments. Some essential TCM herbs started to play a limited role in clinical practices because of Western medication development. For example, Fuzi (Aconiti Lateralis Radix Praeparata) is a toxic but indispensable TCM herb. Fuzi was mainly used in poor circulation and life-threatening conditions by history records. However, with various Western medication options for treating critical conditions currently, how is Fuzi used clinically and its indications in modern TCM are unclear. This study aimed to evaluate Fuzi and Fuzi-based formulas in modern clinical practices using artificial intelligence and data mining methods.Methods: This nationwide descriptive study with market basket analysis used a cohort selected from the Taiwan National Health Insurance database that contained one million national representatives between 2003 and 2010 used for our analysis. Descriptive statistics were performed to demonstrate the modern clinical indications of Fuzi. Market basket analysis was calculated by the Apriori algorithm to discover the association rules between Fuzi and other TCM herbs.Results: A total of 104,281 patients using 405,837 prescriptions of Fuzi and Fuzi-based formulas were identified. TCM doctors were found to use Fuzi in pulmonary (21.5%), gastrointestinal (17.3%), and rheumatologic (11.0%) diseases, but not commonly in cardiovascular diseases (7.4%). Long-term users of Fuzi and Fuzi-based formulas often had the following comorbidities diagnosed by Western doctors: osteoarthritis (31.0%), peptic ulcers (29.5%), hypertension (19.9%), and COPD (19.7%). Patients also used concurrent medications such as H2-receptor antagonists, nonsteroidal anti-inflammatory drugs, β-blockers, calcium channel blockers, and aspirin. Through market basket analysis, for the first time, we noticed many practical Fuzi-related herbal pairs such as Fuzi–Hsihsin (Asari Radix et Rhizoma)–Dahuang (Rhei Radix et Rhizoma) for neurologic diseases and headache.Conclusion: For the first time, big data analysis was applied to uncover the modern clinical indications of Fuzi in addition to traditional use. We provided necessary evidence on the scientific use of Fuzi in current TCM practices, and the Fuzi-related herbal pairs discovered in this study are helpful to the development of new botanical drugs.
Correlations Between Cognitive Functions and Clinical Symptoms in Adolescents With Complex Post-traumatic Stress Disorder
Authors: Shin Yee Jin , Kim Sun Mi , Hong Ji Sun , Han Doug Hyun 
Published: April 2021

Introduction: Complex post-traumatic stress disorder (C-PTSD) is characterized by the typical symptoms of PTSD, in addition to affective dysregulation, negative self-concept, and disturbances in interpersonal relationships. Children and adolescents with C-PTSD have been reported to have deficits in emotional and cognitive functions. We hypothesized that the following are associated with the severity of C-PTSD symptoms: (1) adolescents with C-PTSD who show deficits in emotional perception and cognitive functions, including executive function and attention; and (2) deficits in neurocognitive functions.Methods: Information on 69 adolescents with PTSD, aged 10–19 years, was gathered from seven shelters. All participants were assessed using complete clinical scales, including the C-PTSD Interview and Depression, Anxiety, and Stress Scales, and neurocognitive function tests, including the emotional perception, mental rotation, and modified Tower of London tests.Results: Adolescents with C-PTSD were more likely to have a history of sexual assault, dissociation, and self-harm than those with PTSD. The total and subscale scores of the C-PTSD Interview Scale in adolescents with C-PTSD were higher than that in adolescents with PTSD. In addition, neurocognitive functions, including emotional perception, attention, and working memory, were correlated with the severity of C-PTSD symptoms.Discussion: Adolescents with C-PTSD experienced more serious clinical symptoms and showed more deficits in neurocognitive functions than adolescents with PTSD. Clinicians should pay careful attention toward the emotional and neurocognitive functions when assessing and treating patients with C-PTSD.
أحكام الامتناع عن الفعل في المسؤولية عن الفعل الشخصي
Authors: عبد مثنى محمد 
Published: April 2021

تترتب مسؤولية فاعل الضرر عن خطأه اذا الحق المخطيء ضررا بالغير، وهو امر لاخلاف عليه فقها وقانونا، وهو ما يعر ف بـ (الخطا الايجابي). فمتى وقع الضرر قامت مسؤولية المخطيء. ولا فرق هنا بين ناقص الاهلية او عديمها أو كاملها، فكل من الحق ضررا بالغير تحمل فاعل الضرر المسؤولية عن فعله. ولكن الامر ليس سيان بالنسبة للخطا السلبي، فهل تطبق قواعد الخطا الايجابي في حالة ارتكاب الضرر نتيجة لخطأ سلبي؟. بمعنى آخر هل يتحمل فاعل الضرر المسؤزولية عن الخطا السلبي؟ وهنا تندرج صورة من صور الخطا السلبي او وهي (الامتناع عن الفعل)، وهو الحالة التي يلتزم فيها الفرد بعدم القيام بعمل في الوقت الذي يفرض عليه القانون احيانا القيام بعمل. أو يفرض عليه الواجب القيام بعمل معين. أشكالية البحث: وهنا تثور أشكالية تتلخص في ما ياتي:
1– ما هو الحكم القانوني في حالة امتناع الفرد عن القيام بعمل مفروضا عليه بحكم القانون او بحكم الواجب القانوني العام؟
2– هل يتساوى اثر الامتناع عن الفعل الذي يفرضه الواجب القانوني العام، مع الاثر الذي تفرضه النصوص القانونية الخاصة؟
3– هل يتساوى الحكم على الممتنع ناقص الاهلية، والممتنع كامل الاهلية؟
4– ماهو الحكم اذا كان الممتنع ناقص الاهلية، بمعنى ان يكون الضرر ترتب على امتناع شخصا ما عديم الاهلية؟ 5– وأخيرا ما هو موقف الفقه الاسلامي من هذه المسألة بالذات، وما هي اراء الفقهاء في الموضوع. هذه الاشكاليات جميعها سوف نجيب عنها في هذا البحث ان شاء الله تعالى.
أوجه القصور في الصياغة التشريعية لقوانين الوظيفة العامة
Authors: جعفر رشا محمد 
Published: April 2021

بصدور الدستور الحالي استبشر رجال القانون بصدور العديد من الإصلاحات القانونية وعلى الأخص في مجال الوظيفة العامة , لأهمية الوظيفة العامة باعتبارها تكليف وطني وخدمة اجتماعية يستهدف القائم بها المصلحة العامة وخدمة المواطنين في ضوء القواعد القانونية النافذة وهذا الحكم يتوافق وأحكام الدستور النافذ، فهي خدمة من نوع خاص تهدف إلى تحقيق المصلحة العامة وهي تتكون من الصلاحيات والواجبات والمسؤوليات التي تناط قانوناً للموظف ليؤديها وفق أهداف الدائرة خدمة للمصلحة العامة . فهي ليست امتيازاً لمن يلتحق بها أو تفضلا على الجماهير,لان خدمة الموظف للمواطنين واجب يفرضه القانون عليه ويحاسبه إذا اخل به .
ونظراً للتطور الحاصل في الوظيفة العامة كونها توفر العديد من الوسائل التي تستعين بها الإدارة من اجل تقويم السلوك المعوج وكشف المخالفات المالية والإدارية والجرائم التي يرتكبها العاملين و إبلاغ النتائج التي يتم التوصل إليها لجهات الاختصاص لاتخاذ الإجراء المناسب بشأنها، نلاحظ صدور القوانين والقواعد التي تنظم الوظيفة بشكل مستمر ليواكب تطور العصر ولمواكبة التطور القانوني للخدمة العامة ,وسد أوجه القصور والفراغ لتطوير التشريعات والقوانين وتحديثها باستمرار. ويشكل بحثنا هذا محاولة للكشف عن ابرز اوجه القصور الذي تضمنتها القوانين الصادرة بشأن الوظيفة العامة.
Matrices progresivas de Raven: punto de corte para preescolares 4 - 6 años
Authors: Ramírez Benítez Yaser , Jiménez-Morales Rodneys Mauricio , Díaz Bringas Miriela 
Published: April 2021

A descriptive study was conducted - correlational in several schools in the provinces of Cienfuegos and Matanzas to determine a cut-off of the preschool child 4 to 6 years. Standardization sample (N1) and validation sample (N2): two samples were used. N1 was composed of 406 children: 108 4 years 102 5 years 196 6 years. N2 was composed of 130 children: 30 to 4 years, 50 with 5 years and 50 to 6 years. The receiver -operator curve method was used to select the cut. The validity of the test was obtained through correlation with two reasoning tasks (Similarities - Differences and numerical operations). The Cronbach's alpha indicated the reliability of the test. The test presents suitable for application in presch ool psychometric properties. The cutoffs selected showed appropriate values to detect intellectual risk in preschool.
Construcción y Validación de una Escala para evaluar Indicadores Físicos y Psicoemocionales de Estrés
Authors: Oros de Sapia Laura B. , Neifert Ivan 
Published: April 2021

El propósito de este trabajo es presentar el proceso de construcción y validación del cuestionario de indicadores físicos y psicoemocionales de estrés el cual permite realizar un examen rápido de la sintomatología que experimenta una persona que es expuesta a situación de tensión psicológica. La versión preliminar fue sometida a una prueba piloto con el fin de estudiar sus propiedades psicométricas y, luego de ser modificada, fue administrada a una muestra de 356 sujetos de ambos sexos de la provincia de Entre Ríos. Se obtuvieron buenos indicadores de fiabilidad, validez factorial, validez constructiva y poder discriminativo de los ítem. La escala resultante es de tipo Likert y consta de 22 síntomas que el sujeto debe valorar según el grado de aparición (Nunca, Rara vez, A veces si - A veces no, recuentemente, Siempre). De acuerdo a los resultados del análisis factorial, existen tres dimensiones subyacentes a este conjunto de ítems: a) déficit cognitivo y estado anímico, b) nerviosismo y dificultad para la relajación, y c) síntomas físicos.
Improvement of in-plane uniformity of cathodoluminescence from ZnO luminescent layers for electron beam excitation assisted optical microscope
Authors: Nakamura Atsushi , Inami Wataru , Yamamoto Ryo , Imai Yuma , Kobayashi Shun , Kawata Yoshimasa 
Published: April 2021

Abstract
We fabricated flat and homogeneous Al2O3/ZnO/Al2O3 heterostructure luminescent layers by atomic layer deposition (ALD) to serve as a nanometer-scaled light source for high-spatial-resolution optical microscopy based on electron beam excitation (EXA). A smooth surface was obtained by inserting an Al2O3 buffer layer and an Al2O3 barrier layer resulting in brighter and more uniform cathodoluminescence (CL) compared with that from a directly deposited ZnO layer. The root mean square (rms) value determined by atomic force microscope drastically decreased from 2.4 nm (for typical ZnO film) to 0.5 nm (for the six-layer pairs of the Al2O3/ZnO/Al2O3 heterostructure). The CL brightness increased by two times of that in the Al2O3/ZnO/Al2O3 heterostructure due to a waveguide effect. However, the increase in the number of the layer pairs from one to six reduced the CL brightness by half. The CL emission variability was about 30% improved that is supposed to enable high-resolution using Al2O3/ZnO/Al2O3 luminescent layers for an EXA microscope.
Laser oscillation of an organic distributed-feedback laser at the edge of a mini stopband
Authors: Miura Taiki , Kanagasekaran Thangavel , Shimotani Hidekazu , Tanigaki Katsumi 
Published: April 2021

Abstract
The conditions for determining the oscillation wavelength of organic distributed-feedback (DFB) lasers were investigated by employing 5,5″-bis(biphenyl-4-yl)-2,2′:5′,2″-terthiophene (BP3T) single crystals with various thicknesses as an active layer. Analysis using experimentally obtained refractive indexes revealed that the oscillation wavelengths of some BP3T DFB lasers are at the edge of a stopband, whereas the others are at an edge of a mini stopband, which satisfies the phase-matching condition among different transverse modes and has not been considered in DFB lasers so far. The coupling of different transverse modes was verified by finite-element optical-waveguide simulations of the BP3T DFB laser.
TREND POLA ASUH ORANG TUA DALAM MODEL PEMBELAJARAN BLENDED LEARNING PADA MASA PANDEMI COVID-19
Authors: Anggraeni Cindra Suryaputri , Hidayati Nur , K Khoirulliati , Farisia Hernik 
Published: April 2021

This study discusses parenting styles in assisting students’ learning with blended learning model in RA. Sunan Ampel, Pasuruan. During the Covid-19 pandemi, RA Sunan Ampel implemented a blended learning model by combining online and offline learning. The instrument used in this study was a questionnaire distributed online to 11 parents of RA students as respondents. The results showed that almost parents have a authoritative parenting style indicated by parents’ attitude in engaging children to learning while playing. Meanwhile, such parents also applied permissive parenting characterized by parents’ intervention on children’s activites and no force for children to learn. Besides that, parents with authoritarian showed that they obey strict rules and punishments when children broke the rules. Above all, such uninvolved parenting implemented during the covid-19 indicated by negligent attitude of parents in engaging students’ learning.
Value of Neutrophil-Lymphocyte Ratio (NLR), Monocyte-Lymphocyte Ratio (MLR), Absolute Lymphocyte Count (ALC) and Procalcitonin in Patients in Covid-19 Monitoring (PDP) at Dr. Saiful Anwar Malang Hospital
Authors: Octavia Umi Fatma , Chozin Iin Nur , Sugiri Yani Jane 
Published: April 2021

Background: The Covid-19 pandemic which is currently sweeping the world is an infectious disease that has only recently been identified and provides challenges for experts in dealing with and overcoming its spread. Fast and precise diagnostics are needed for the appropriate management of Covid-19. The value of the neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), absolute lymphocyte count (ALC) have been investigated for their potential and ability as a diagnostic and prognostic approach. In Indonesia alone the spread of Covid-19 is quite high and alarming. Evidence of characteristics and clinical manifestation of Covid-19 is imperative.
Methods: This study was an observational analytic study of hematological laboratory parameters that measured the values of NLR, MLR, ALC, and procalcitonin in patients under Covid-19 monitoring. All data were obtained from the medical records of patients treated in the isolation ward of the emerging and re-emerging infectious disease at Dr. Saiful Anwar Hospital Malang. This study also compared these variables between groups of patients confirmed by Covid-19 and those that were not confirmed, in order to identify the characteristics of patients in Covid-19 monitoring at Dr. Saiful Anwar Hospital Malang.
Results: From 40 study subjects, the average age of all subjects was 49.58 ± 16.42 years. The confirmed cases of Covid-19 tend to be younger compared to the unconfirmed, in the age range of 15-49 years . The majority of the sex of the study subjects were male, with the predominance of the female in the confirmed patient group. The most prominent complaints are coughing and shortness of breath, while the most common co-morbidity is hypertension. The NLR, MLR, ALC, and procalcitonin values of patients confirmed Covid-19 did not differ significantly from those unconfirmed. The length of stay between the two groups was 7.8 ± 2.44 days for Covid-19 confirmed patients and 5.65 ± 3.08 days for unconfirmed Covid-19 patients.
Conclusion: The results of this study show that patients with suspicion of Covid-19 in Dr. Saiful Anwar Hospital Malang are dominated by young adults . There were no significant differences of NLR, MLR, ALC, and Procalcitonin in either confirmed and non-confirmed Covid-19 patients.
Metástasis de los simulacros y metástasis digital en "La novela perfecta" de Carmen Boullosa
Authors: López Pellisa Teresa 
Published: April 2021

Hemos diagnosticado como metástasis de los simulacros a la patología que se produce en algunos textos cuya temática gira en torno a la realidad virtual. La podemos detectar cuando analizamos la función del incremento de niveles de simulación, a través de lo que hemos denominado metadiégesis digital. Con esta herramienta podemos diseccionar los diversos niveles de virtualidad y realidad virtual generados por máquinas digitales en los textos literarios y cinematográficos de ciencia ficción, partiendo de las teorías de Gérard Genette. A partir de su concepto de “metadiégesis”, proponemos el sintagma “metadiégesis digital”, para hacer referencia a todos aquellos relatos en segundo grado que están generados por la tecnología digital. De este modo, siempre que los personajes de un texto desarrollen parte de la historia en un entorno de realidad virtual o en el ciberespacio, convivirán con diversos planos de realidad textual (real y digital), siendo la metadiégesis digital el nivel narrativo producido por la máquina. Aplicaremos el concepto de metástasis de los simulacros a La novela perfecta de Carmen Boullosa.
Apuntes sobre el realismo en las narraciones visuales actuales. El ejemplo de la adaptación cinematográfica del cómic "María y yo" de Miguel Gallardo por Félix de Castro
Authors: Touton Isabelle 
Published: April 2021

Se analiza primero la manera como se plantea la cuestión del "realismo" (sus dimensiones estéticas, sociológicas, pragmáticas, editoriales…) según los lenguajes narrativos y soportes artísticos involucrados (novela, cine, cómic). Luego, se parte de dos novelas gráficas de 2007 (Arrugas, de Paco Roca, y María y yo, de Miguel Gallardo) y sus adaptaciones cinematográficas (Arrugas, película de animación de Ignacio Ferrero, y María y yo, documental de Félix Fernández de Castro), para intentar mostrar en qué medida esta última obra, al mezclar acercamientos "realistas" o "idealistas", logra aprehender un objeto digno de interés desde varias miradas respetadas en su singularidad, llevar a cabo una reflexión acerca del estatuto de lo real (en el que incluye la imaginación utópica), y consigue influir en la realidad.
Around Which Stars Can TESS Detect Earth-like Planets? The Revised TESS Habitable Zone Catalog
Authors: Kaltenegger L. , Pepper J. , Christodoulou P. M. , Stassun K. , Quinn S. , Burke C. 
Published: April 2021

Abstract
In the search for life in the cosmos, NASA’s Transiting Exoplanet Survey Satellite (TESS) mission has already monitored about 74% of the sky for transiting extrasolar planets, including potentially habitable worlds. However, TESS only observed a fraction of the stars long enough to be able to find planets like Earth. We use the primary mission data—the first two years of observations—and identify 4239 stars within 210 pc that TESS observed long enough to see three transits of an exoplanet that receives similar irradiation to Earth: 738 of these stars are located within 30 pc. We provide reliable stellar parameters from the TESS Input Catalog that incorporates Gaia DR2 and also calculate the transit depth and radial velocity semiamplitude for an Earth-analog planet. Of the 4239 stars in the Revised TESS HZ Catalog, 9 are known exoplanet hosts—GJ1061, GJ1132, GJ3512, GJ685, Kepler-42, LHS1815, L98-59, RRCae, and TOI700—around which TESS could identify additional Earth-like planetary companions. Thirty-seven additional stars host yet unconfirmed TESS Objects of Interest: three of these orbit in the habitable zone—TOI203, TOI715, and TOI2298. For a subset of 614 of the 4239 stars, TESS has observed the star long enough to be able to observe planets throughout the full temperate, habitable zone out to the equivalent of Mars’ orbit. Thus, the Revised TESS Habitable Zone Catalog provides a tool for observers to prioritize stars for follow-up observation to discover life in the cosmos. These stars are the best path toward the discovery of habitable planets using the TESS mission data.
The Anatomy of an Unusual Edge-on Protoplanetary Disk. II. Gas Temperature and a Warm Outer Region
Authors: Flores C. , Duchêne G. , Wolff S. , Villenave M. , Stapelfeldt K. , Williams J. P. , Pinte C. , Padgett D. , Connelley M. S. , van der Plas G. , Ménard F. , Perrin M. D. 
Published: April 2021

Abstract
We present high-resolution 12CO and 13CO 2–1 ALMA observations, as well as optical and near-infrared spectroscopy, of the highly inclined protoplanetary disk around SSTC2D J163131.2–242627. The spectral type we derive for the source is consistent with a 1.2 M
⊙ star inferred from the ALMA observations. Despite its massive circumstellar disk, we find little to no evidence for ongoing accretion on the star. The CO maps reveal a disk that is unusually compact along the vertical direction, consistent with its appearance in scattered light images. The gas disk extends about twice as far away as both the submillimeter continuum and the optical scattered light. CO is detected from two surface layers separated by a midplane region in which CO emission is suppressed, as expected from freeze-out in the cold midplane. We apply a modified version of the tomographically reconstructed distribution method presented by Dutrey et al. to derive the temperature structure of the disk. We find a temperature in the CO-emitting layers and the midplane of ∼33 K and ∼20 K at R < 200 au, respectively. Outside of R > 200 au, the disk’s midplane temperature increases to ∼30 K, with a nearly vertically isothermal profile. The transition in CO temperature coincides with a dramatic reduction in the submicron and submillimeter emission from the disk. We interpret this as interstellar UV radiation providing an additional source of heating to the outer part of the disk.
Cyber- ou Cerbère-thérapie ? À propos de la visio- ou téléconsultation au temps de la covid-19
Authors: Bormans Christophe 
Published: April 2021

La pandémie de covid-19 et la période de confinement ont bouleversé la pratique psychanalytique standard et le cadre analytique traditionnel mis en place par Freud. Analystes et analysants étant, les uns dans l’impossibilité de recevoir, les autres dans celle de se déplacer, la psychanalyse laïque a dû s’adapter. Afin de garder le lien analytique, bon nombre de psychanalystes ont dû pratiquer autrement : fini l’usage du divan, place à l’internet, aux messageries instantanées, aux appels téléphoniques ou vidéo, bref, à ce que l’on pourrait appeler la télé- ou visioanalyse. Au-delà de ces cyber-préfixes, peut-on toujours parler de « psychanalyse » ? Tenter de répondre à cette interrogation, c’est d’abord s’apercevoir que Freud avait déjà, de son temps, anticipé bon nombre des évolutions de la pratique qu’il a fondée, en détaillant même assez précisément les avantages et inconvénients de celles-ci. Plus globalement, s’il n’est pas possible de nier ses ressorts thérapeutiques, une telle évolution semble plutôt opérer un retour en arrière sur le chemin même de l’invention de la psychanalyse, précisément en ce qu’elle semble participer d’un retour à l’hypnose et à la suggestion, dont Freud ne manque pas de se départir au moment même de l’acte fondateur de la psychanalyse. Aussi, le discours qui soutient ce type de thérapie semble céder sur les trois conceptions spécifiques – et intimement nouées – que Freud a forgées pour sa pratique, que sont l’inconscient, le transfert et les résistances.