bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cementation exponent estimate in carbonate reservoirs: A new method
Authors: Shirazy Adel , Khayer Keyvan , Shirazi Aref , Ansari Abdolhamid , Hezarkhani Ardeshir 
Published: September 2021

There are two approaches for measuring hydrocarbon saturation: well log interpretation and usually developed formulas. Archie’s equation is one of the most fundamental equations used for water saturation calculation. Archie’s equation includes three factors: cementation factor, tortuosity and saturation exponent. Archie determines these factors based on lab results in sandstone and provides fixed value for them. Carbonate reservoirs have a variety of textures, shapes and distribution of pores; therefore, the mentioned factors, especially cementation are not considered constant. In this study, the relationship between cementation factor and density log was examined because cementation factor is defined as a parameter that has a close relationship with density. By calculating the matrix density and accordance factor between the matrix density and cementation factor from core’s analysis, a log will be generated that can estimate the variation of cementation factor around the borehole. This method is useable for calculating the cementation factor in carbonate rocks.

Keywords: Cementation factor, carbonate reservoir, density, new method, exponents.
Pulmoner emboli vakalarında AngioJet yardımı ile yapılan reolitik farmako-mekanik trombektomi uygulamalarında anestezi deneyimimiz
Authors: İNANGİL Gökhan 
Published: September 2021

Amaç: Bu çalışmada pulmoner emboli endikasyonu ile reolitik trombektomi uygulanan olgulardaki erken dönem anestezi deneyimlerimizi sunmayı amaçladık.
Gereç ve Yöntem: Eylül 2016-Mayıs 2018 tarihleri arasında pulmoner emboli tanısı ile hibrit ameliyathanede AngioJet reolitik trombektomi uygulanan 25 hasta retrospektif olarak incelendi. Hastaların demografik verileri, ameliyat sırasında ve sonrasında gelişen komplikasyonlar değerlendirildi.
Bulgular: AngioJet yardımı ile reolitik trombektomi uygulanan toplam 25 hastada (11 erkek, 14 kadın; ort. yaş 61,4 ± 14,9 yıl; dağılım 22-83 yıl) lokal anestezi ile birlikte sedasyon uygulamalasının tercih edildiği görüldü. İşlem esnasında bradikardi ve öksürük sık olarak karşımıza çıkan yan etkiler olarak belirlendi. İki hastamızda öksürük sonrası hemoptizi gelişti. Hasta pozisyonuna veya anesteziye bağlı komplikasyon gelişmedi.
Sonuç: Gelişen yeni cerrahi ve perkütan girişimsel tekniklere paralel olarak anestezi uzmanları da uygun anestezi planı ve yönetim stratejisi oluşturmalıdır. Perkütan temelli girişimsel yöntemlerin, özellikle hibrit ameliyathanelerde ve kardiyak anestezi prensipleri uygulanarak yakın monitörizasyon ile izlenmesi gerektirmektedir. Bununla beraber oluşabilecek komplikasyonlar ve acil cerrahi embolektomi ihtiyacı oluşabileceği akılda tutulmalıdır.
Klinik ön tanı ve elektrofizyolojik tanılar arasındaki tutarsızlık: 3. basamak elektronörofizyoloji laboratuvarı retrospektif verileri
Authors: ALTUNIŞIK Erman , ARIK Ali 
Published: September 2021

Amaç: Bu çalışmanın amacı elektrofizyoloji laboratuvarına yönlendirilen hastaların ön tanısı ile elektronöromiyografi incelemesi sonrası ortaya konulan elektrofizyolojik tanı uyumunun araştırılmasıdır.
Gereç ve Yöntem: Retrospektif dizayn edilen bu çalışmaya elektrofizyoloji laboratuvarına 2019 yılı içinde başvuran ve elektronöromiyografi incelemesi yapılan 1314 hasta dahil edildi. Hastalara ait yaş, cinsiyet gibi sosyodemografik özellikler, ön tanı, ön tanının yapıldığı klinik, elektrofizyolojik inceleme sonucunda elde edilen tanı, ön tanı ile elektrofizyolojik inceleme sonrasında elde edilen tanının tutarlılığı gibi veriler medikal kayıtlardan elde edildi.
Bulgular: Çalışmaya 784’ü (%59,7) kadın, 530’u (%40,3) erkek toplam 1314 hasta dahil edildi. Elektronöromiyografi sonuçlarına göre hastaların %61,4’inin (n=807) incelemesi normal olarak değerlendirildi. Hastaların %34,9’inde (n=458) ön tanılarla elektronöromiyografi tanıları uyumlu bulunurken, %3,7’ne (n=49) ise ön tanılardan farklı patolojik elektrofizyolojik tanılar konuldu. Ön tanılarla elektronöromiyografi tanıları arasında uyum oranlarına bakıldığında poliomyelit, periferik sinir hasarı ve kranial nöropati ön tanılarının tanısı ile uyum oranları diğer ön tanılardan anlamlı derecede yüksekti. Erkek cinsiyetin tanı uyumu kadın cinsiyete oranla anlamlı derecede yüksek saptandı. Yaş arttıkça tanı uyumunun yaşla korele olarak arttığı görüldü.
Sonuç: Elektronöromiyografi sadece tanı koymada değil ayırıcı tanı yapma ve ön tanıyı dışlama konusunda da kullanılmaktadır. Tetkik öncesinde ayrıntılı nörolojik muayene yapılması ve uygulayıcı hekimin bilgilendirilmesi gereksiz bazı işlemleri azaltabilir
Relationship of multiple myeloma with ABO blood groups
Authors: YANARDAĞ AÇIK Didar , BANKİR Mehmet , AVCİ Begüm Seyda 
Published: September 2021

Aim: Multiple myeloma is a heterogeneous, incurable haematological cancer that occurs as a result of the clonal proliferation of plasma cells. The impact of blood groups on human diseases and/or their role in the prognosis of the disease has attracted the attention of scientists since the discovery of blood groups. We investigated the blood group distribution of multiple myeloma patients and whether their blood groups are related to immunoglobulin type.
Materials and Methods: 75 multiple myeloma patients and 73128 control group were included in the study, which was planned retrospectively. The statistical evaluation was performed by using Statistical Package for Social Sciences (SPSS) software for Windows 20 (IBM SPSS Inc., Chicago, IL). The normal distribution of the data was evaluated with the Kolmogorov-Smirnov test.
Results: In multiple myeloma patients, the rate of A and B blood groups was low, and the rate of O and AB blood groups was high. Heavy chain IgA ratio was higher in B blood group compared to other blood groups. On the other hand, IgG ratio was found higher in O blood group compared to other blood groups.
Conclusion: A relationship has been found between immunoglobulin type and blood types in multiple myeloma. More comprehensive studies are needed on this subject.
CHOOSING A QUALITY CRITERION FOR EVALUATING THE FORECAST OF NONLINEAR NON-STATIONARY PROCESSES
Authors: Belas Andrii O. , Bidyuk Petro I. 
Published: September 2021

Background. The problem of forecasting nonlinear nonstationary processes presented in the form of time series is very relevant, since such series can describe dynamics of the processes in both technical and economic systems. To establish the best model, various metrics are used to assess the quality of forecasts, such as R^2, RMSE, MAE, MAPE. However, in many tasks, when optimizing the model according to the selected criterion, the model becomes worse in relation to another criterion. Therefore it is important to understand which metric must be used to optimize and assess the quality of the forecast in the given task.
Objective. The aim of the paper is to develop a criteria base for assessing forecasts of nonlinear nonstationary processes, as well as an approach to choosing a metric in accordance to the specificity of the set forecasting problem.
Methods. The paper presents a comparative analysis of the basic metrics for the regression problem, their theoretical and practical meaning, advantages and disadvantages in various cases. New approaches are proposed based on the results of the analysis.
Results. Based on the analysis of the selected data, it is shown that by optimizing the model according to the selected criterion, the model becomes worse in relation to another criterion. A criterion basis for assessing forecasts of nonlinear nonstationary processes has been formed, as well as an approach to the selection of a quality criterion in accordance with the specifics of the set forecasting problem. To minimize an absolute error, the RMSE (MSE, R^2) and MAE metrics are analysed and recommended, depending on the need to work with outliers. The RMSLE metric is proposed for solving the problems of minimizing the relative metric, for solving the shown problems of the MAPE metric for this class of problems.
Conclusions. The paper shows the importance of choosing a metric that must be used to optimize and assess the quality of the forecasts in the given task. The obtained criterion base and approach can be used in further research to solve practical prob- lems in modelling and forecasting nonlinear nonstationary processes and to develop new methods or general method for solving such problems.
Medial and Lateral Patellar Instability Leading to Medial Patellofemoral Ligament and Lateral Retinaculum Reconstruction
Authors: Stokey Phillip J. , Kennedy Hannah V. , Cross Jeffery M. , Sohn David H. 
Published: September 2021

Case:
Combined medial and lateral patellar instability is exceptionally rare with only 3 reported cases to date. Here, we present the case of a 37-year-old White woman with multiple recurrent medial and lateral patellar instability. After failure of conservative care with bracing and therapy, she underwent surgical stabilization with medial and lateral allograft reconstruction.

Conclusion:
This case provides an example of the condition and successful surgical follow-up.
Clinical Outcome of Kissing Mosaicplasty for Treatment of Asymmetric Medial Tibiotalar Osteoarthritis
Authors: Sifen Lena , Van Steyn Peter , Romash Michael M. 
Published: September 2021

Case:
We report a case of asymmetric medial ankle arthritis that was treated by medial malleolar osteotomy and oblique fibular osteotomy to expose and resurface both the medial talar dome and medial tibial plafond articular surfaces.

Conclusion:
This technique permitted a unique application of mosaicplasty in which osteochondral plugs were placed in a “kissing” orientation. The outcome seen here suggests the possibility of mosaicplasty as a viable option for treatment of localized ankle arthritis. In addition, this exposure technique is also applicable to treating isolated lesions of the medial tibial plateau.
Total Shoulder Arthroplasty in a Patient with Nail-Patella Syndrome
Authors: Kawashima Kenji , Terabayashi Nobuo , Asano Hiromi , Akiyama Haruhiko 
Published: September 2021

Case:
A 62-year-old woman with a medical history of nail-patella syndrome (NPS) presented with chronic right shoulder pain. Physical examination revealed that her right shoulder had a restricted range of motion. Radiograph of the shoulder revealed arthritic changes with glenohumeral joint space narrowing, inferior humeral head osteophytes, and posterior glenoid wear. The patient was successfully treated with total shoulder arthroplasty (TSA). The patient had an uneventful postoperative course and was satisfied with her quality of life at the 30-month follow-up.

Conclusion:
TSA may be successfully performed with careful reaming of the hypoplastic glenoid fossa in patients with NPS.
Isolated Open Dislocation of the Capitate
Authors: Janish Tyler , Blotter Robert 
Published: September 2021

Case:
We present a case of an isolated palmar, open dislocation of the capitate that occurred after a crush injury from an all-terrain vehicle rollover accident. The capitate was completely dislocated, rotated 90 degrees in the coronal plane with only soft-tissue attachments palmarly, and associated with a 4 cm open wound. A successful outcome was achieved via surgical reduction with percutaneous fixation. A follow-up at 44 months demonstrated good range of motion and no pain.

Conclusion:
Capitate dislocations are extremely rare. Prompt identification and surgical reduction can lead to successful outcomes.
Femoral Neck Over-Resection After Hip Arthroscopy Treated with Vascularized Fibula Autograft
Authors: Rodkey Daniel L. , Dickens Jonathan F. , Tintle Scott 
Published: September 2021

Case:
We describe a case of femoroacetabular impingement syndrome treated with labral repair and arthroscopic femoral osteoplasty in a 30-year-old man. The case was complicated by resection of 50% of the femoral neck resulting in high risk of an impending femoral neck fracture. The patient was treated with a vascularized fibula autograft and internal fixation.

Conclusion:
Complications of femoral neck over-resection can threaten the viability and structural integrity of the hip joint but may successfully be treated with vascularized fibula autograft.
Multi-reference Computational Method for De-novo Design, Optimization, and Repositioning of Pharmaceutical Compounds Illustrated by Identifying Multi-target SARS-CoV-2 Ligands
Authors: Alexandrov Vadim , Kirpich Alexander , Gankin Yuriy 
Published: September 2021

Abstract
In this work a novel computational multi-reference poly-conformational algorithm is presented for design, optimization, and repositioning of pharmaceutical compounds. The algorithm searches for candidates by comparing similarities between conformers of the same compound and identifies target compounds whose conformers are simultaneously “close” to the conformers for each of the compounds in a reference set. The reference compounds can have very different MoAs, which directly and simultaneously shapes the properties of the target candidate compounds. The algorithm functionality has been validated in silico by scoring ChEMBL drugs against FDA-approved reference compounds which either had the highest predicted binding affinity to our chosen SARS-COV-2 targets or confirmed to be inhibiting such targets in-vivo. All our top scoring ChEMBL compounds also turned out to be either high-affinity ligands to the chosen targets (as confirmed separately in other studies) or showing significant efficacy in-vivo against those selected targets.In addition to method validation in silico search for new compounds within two virtual libraries from the Enamine database is presented. The library’s virtual compounds have been compared to the same set of reference drugs that we used for validation: Olaparib, Tadalafil, Ergotamine and Remdesivir. The large reference set of four potential SARS-CoV-2 compounds have been selected, since no drug has been identified to be 100% effective against the virus so far, possibly because each candidate drug was targeting only one particular MoA. The goal here was to introduce methodology for identifying potential candidate(s) that cover multiple MoA-s presented within a set of reference compounds.
Novel Combination of Quaternary AgFeNi2S4 Semiconductor In Graphene-TiO2 Nanocomposite For The Enhanced Electrophotocatalytic Reduction of CO2
Authors: Otgonbayar Zambaga , Oh Won Chun 
Published: September 2021

Abstract
For reduction of CO2 into hydrocarbon fuels, a quaternary AgFeNi2S4 semiconductor combined in Graphene-TiO2 nanocomposite material was synthesized via the Pechini method. The catalytic activity of the photocatalyst for photocatalytic and electrochemical CO2 evolution into hydrocarbon fuels was tested. The methanol yield under UV light was 8.679, 6.349, and 4.136 %, and the methanol yields under visible light were 6.291, 4.738, and 2.339 %, respectively. The stability and reusability of the photocatalyst remained high after a 4-cycle recycling test without a decrease in yield of the final photocatalytic CO2 reduction product. The enhanced photoreduction of CO2 through the as-prepared ternary photocatalyst can be ascribed to the catalyst's conformation and low recombination rate. In electrochemical CO2 reduction, the Faraday efficiency is the main parameter that defines the performance of the working electrode and the evolution of methanol. The Faraday efficiency of AFNSGT ternary nanocomposite was 44.25 %; this is an increase in the value of the Faraday efficiency, which proves that the design of the new nanocomposite successfully increases the activity of the working electrode and has a positive effect on the electrochemical reduction of CO2. The photocatalytic and electrochemical CO2 reduction data show that the preparation method, morphological state, and charge carrier properties of the photocatalyst are important for the catalytic activity and efficiency of the methanol evolution pathway.
Effects of Extended Feeding of Florfenicol Coated Medicated Diets on the Safety, Serum Biomarkers and Blood Cells Morphology of Nile Tilapia Oreochromis Niloticus (L.) Juveniles
Authors: Bardhan Avishek , Abraham Thangapalam Jawahar , Singha Jasmine , Saha Suchismita , Sarker Sudeshna , Patil Prasanna Kumar 
Published: September 2021

Abstract
Tilapia is one of the most consumed farmed fish, which requires the use of antibiotics in certain phases of its production. This study assessed the safety of 30 days of oral florfenicol (FFC)-dosing at 0-10 times the therapeutic dose (1X: 10 mg/kg biomass/day) in Oreochromis niloticus juveniles. Behavioural changes, feed consumption, mortality and biomass were evaluated. Besides, the levels of serum glucose, calcium, chloride, creatinine, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and blood cell morphology were determined at scheduled intervals. The 30 days of oral FFC-dosing caused 3.33% (1X) to 18.33% (10X) mortalities, reduced feed intake and biomass in a dose-dependent manner. The fish fed the therapeutic dose recorded 1.25 folds increase in biomass; while the control group recorded 1.45 folds increase in 30 days. No significant erythrocyte morphological alterations were observed in the 1X group compared to the control. However, marked morphological alterations like tear-shaped, spindle-shaped and degenerative erythrocytes in higher dosing groups indicated FFC cytotoxicity. All the serum biomarkers of O. niloticus increased significantly on day 10 and day 30 FFC-dosing in a dose-dependent manner, except for calcium and chloride, which reduced significantly during the dosing period. Within 2 weeks of suspension of FFC-dosing, the serum biomarker levels became normal except for alkaline phosphatase and creatinine. The recovery of biomass, feed intake, serum biomarker levels and erythrocyte morphological changes suggested that the FFC induced changes are reversible. This study has, thus, proclaimed the safety of FFC at the therapeutic dose in O. niloticus.
Tumor Angiogenesis at Baseline Identified by 18F-Alfatide II PET/CT May Predict Survival Among Patients with Locally Advanced Non-Small Cell Lung Cancer Treated with Concurrent Chemoradiotherapy
Authors: Wei Yuchun , Qin Xueting , Liu Xiaoli , Zheng Jinsong , Luan Xiaohui , Zhou Yue , Yu Jinming , Yuan Shuanghu 
Published: September 2021

Abstract
Background The study investigated the predictive value of tumor angiogenesis observed by 18F-ALF-NOTA-PRGD2 II (denoted as 18F-Alfatide II) positron emission tomography (PET)/computed tomography (CT) before concurrent chemoradiotherapy (CCRT) for treatment response and survival among patients with locally advanced non-small cell lung cancer (LA-NSCLC).Methods Patients with unresectable stage IIIA or IIIB NSCLC (AJCC Cancer Staging 7th Edition) who received CCRT were included in this prospective study. All patients had underwent 18F-Alfatide PET/CT scanning before CCRT, and analyzed parameters included maximum uptake values (SUVmax) of primary tumor (SUVP) and metastatic lymph nodes (SUVLN) and mean uptake value of blood pool (SUVblood). Tumor-to-background ratios (TBRs) were calculated. The ratios of SUVP to SUVblood, SUVLN to SUVblood, and SUVP to SUVLN were denoted as TBRP, TBRLN, and T/LN. Short-term treatment response, progression-free survival (PFS), and overall survival (OS) were evaluated.Results Of 38 enrolled patients, 28 completed CCRT. SUVP, SUVLN, TBRP, TBRLN and T/LN showed significant correlation with PFS (all P<0.05). SUVP was negatively correlated with OS (P=0.005). SUVP and TBRP were higher in non-responders than in responders (6.55±2.74 vs. 4.61±1.94, P=0.039; 10.49±7.58 vs. 7.73±6.09, P=0.023). Exploratory receiver operating characteristic curve analysis identified TBRP (area under the curve [AUC]=0.764, P=0.018), with a cutoff value of 6.52, as the only parameter significantly predictive of the response to CCRT, with sensitivity, specificity, and accuracy values of 71.43%, 78.57%, and 75.00%, respectively. ROC curve analysis also identified SUVP (AUC=0.942, P<0.001, cutoff value 4.64) and TBRP (AUC=0.895, P=0.001, cutoff value 4.95) as predictive of OS with high sensitivity (84.21%, 93.75%), specificity (100.00%, 66.67%), and accuracy (89.29%, 82.14%).Conclusions Evaluation of tumor angiogenesis by 18F-Alfatide Ⅱ at baseline may be useful in predicting the short-term response to CCRT as well as PFS and OS in patients with LA-NSCLC.
Analysis of E-mental Health Research: Mapping the Relationship between Information Technology and Mental Healthcare
Authors: timakum tatsawan , Song Min , Xie Qing 
Published: September 2021

Abstract
Background: E-mentalhealthcare is the convergence of digital technologies with mental health services. It has beendevelopedto fill a gap in healthcare for people who need mental wellbeing support and may never otherwise receive psychological treatment.This study aimed to apply text mining techniques to analyze the huge data of e-mental health researches and to report on research clusters and trends as well as the co-occurrence of biomedical and the use of information technology in this field.Methods: The e-mentalhealth research data was obtainedfrom 3,663 bibliographicrecords from Web of Science (WoS)and 3,172 full-text articlesfrom PubMed Central (PMC). The text mining techniques utilized for this study includedbibliometric analysis, information extraction, and visualization.Results: The e-mental health research topic trendsprimarily involvede-health care services and medical informatics research. The clusters of research comprise 16 clusters, which refer to mental sickness, ehealth, diseases, IT, and self-management. Based onthe information extraction analysis, in the biomedical domain, a “depression” entity was frequently detected and it pairs with other entities in the network with a betweenness centrality weighted at 0.046869 (eg. depression-online, depression-diabetes, depression-measure, and depression-mobile).The IT entity-relations of “mobile” were the most frequently found(weighted at 0.043466). The top pairs are related to depression, mobile health, and text message.Conclusions: E-mental health research trends focused on disease related-depression and using IT for treatment and prevention, primarily via online and mobile devices. Producing AI and machine learning are also being studied for e-mental healthcare. The results illustrate that physical sickness is likely to cause a mental health problem and identify the IT that was applied to help manage and mitigate mental health impacts.