bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supragingival Microbiome Alternations as a Consequence of Smoking Different Tobacco Types and Its Relation to Dental Caries
Authors: Al-Marzooq Farah , Kawas Sausan Al , Rahman Betul , Shearston Jenni A. , Saad Hiba , Benzina Dalenda , Weitzman Michael 
Published: September 2021

Abstract
This study aimed to assess the effect of smoking different tobacco types on the supragingival microbiome and its relation to dental caries. Forty supragingival plaques were collected from smokers of a single tobacco type and non-smokers seeking treatment at the University Dental Hospital Sharjah, UAE. DMFT (decayed, missing and filled teeth) was determined for all participants who were divided into two groups: no-low caries (NC-LC: DMFT= 0-4; n=18) and moderate-high caries (MC-HC: DMFT= 5-20; n=22). 16S rRNA gene was sequenced using third-generation sequencing with Nanopore technology. Microbiome composition and diversity were compared. Caries were most common among cigarette smokers. Supragingival microbiota were significantly altered among smokers of different tobacco types. In cigarette smokers, cariogenic bacteria from genus Streptococcus (including S. mutans) were significantly more among subjects with NC-LC, while Lactobacilli (including L. fermentum) were more among subjects with MC-HC. In medwakh smokers, several periodontopathogens were significantly elevated in subjects with NC-LC, while other pathogenic bacteria (as Klebsiella pneumoniae) were more in those with MC-HC. Cigarette and alternative tobacco smoking had a significant impact on the supragingival microbiome. Dysbiosis triggered by smoking can be a predisposing factor to caries. Tobacco cessation and oral health-promoting strategies are required to prevent dental caries when the oral microbiome is disturbed.
Exploring Housing Policies in Five Swedish Municipalities: Alternatives and Priorities
Authors: Heller Christina , Ekstam Lisa , Haak Maria , Schmidt Steven M. , Slaug Björn 
Published: September 2021

Abstract
Introduction: Housing shortage due to population growth within metropolitan areas, combined with an ageing population has put pressure on current housing provision policies in Sweden. Thus, there is an urgent need to develop sustainable housing policies to accommodate the growing number of seniors in accessible home environments. This study aimed to gain an in-depth understanding of how municipalities currently address housing accessibility issues and to explore what types of policy solutions they consider for the future.Material and methods: Five Swedish municipalities were selected to represent a diversity of the population, housing provision approaches, and geographical areas. To understand current housing policies, two key actors (e.g. public officials, housing adaptation grant managers, city architects, etc.) from each municipality participated in semi-structured interviews (N=10). Subsequently, those key actors, two senior citizens, and three researchers participated in a research circle to explore future policy solutions. Data were analyzed using content analysis.Results: The interviews revealed common approaches to deal with housing accessibility issues such as regular renovations and maintenance, individual adaptations based on specific needs, and seeking collaboration with private housing actors on housing provision matters. Possible measures suggested for the future included increasing the national coordination of housing accessibility policies, amending legislation to only allow the construction of housing according to strengthened accessibility standards, and introducing economic incentives for seniors to move from housing with poor accessibility to more accessible accommodations,Conclusions: Municipalities struggle with the lack of accessible and affordable housing for the ageing population. The results suggest that collaboration needs to be improved between all actors involved in housing policies. The overall housing standard in Sweden is high, but preventive measures within the current law may be needed to strengthen the construction of more accessible and affordable housing for the population ageing in place.
Influence of Impulse Moments On Single-Frequency Torsional Oscillations of Nonlinearly Elastic Bodies
Authors: Sokil Mariia , Andrukhiv Andriy , Fedushko Solomiia , Kryvinska Natalia , Syerov Yuriy , Yurkiv Maria 
Published: September 2021

Abstract
Analytical study of the impulse moment influences on the nonlinear torsional oscillations in the homogeneous constant cross-section of a body under classical boundary conditions of the first, second, and third types has been developed. For the case when the elastic material properties meet the body close to the power law of elasticity, mathematical models of the process are obtained. They are the boundary value problems for an equation of hyperbolic type with a small parameter at the discrete right-hand side. The latter expresses the effect of pulse momentum on the oscillatory process. The peculiarities of resonant oscillations are established. Relative torsional oscillations of a nonlinear elastic body that rotates around the axis with a constant portable angular velocity are considered, taking into account the periodic action of pulse momentum acting in a fixed cross-section. The reliability of the obtained calculation formulas is confirmed.
Effects of Process Factors on Performances of Liquid Membrane-Based Transfer of Indole-3-Acetic Acid
Authors: Diaconu Ioana , Pârvulescu Oana Cristina , Topală Sorina Laura , Dobre Tănase 
Published: September 2021

Abstract
The paper has aimed at studying the transfer of indole 3-acetic acid (IAA) from a feed aqueous solution to a stripping aqueous solution of NaOH using a chloroform bulk liquid membrane and trioctylamine (TOA) as a ligand (L). Initial molar concentrations of IAA in the feed phase, cIAA,F0 (10-4-10-3 kmol/m3), of TOA in the membrane phase, cL,M0 (10-2 and 10-1 kmol/m3), and of NaOH in the stripping phase, cNaOH,S0 (10-2 and 1 kmol/m3), were selected as process factors. Their effects on the final values of IAA concentration in the feed phase (cIAA,Ff) and stripping solution (cIAA,Sf), extraction efficiency (EF), distribution coefficient (KD), and recovery efficiency (ER) were quantified using multiple regression equations. Regression coefficients were determined from experimental data, i.e., cIAA,Ff,ex=0.02-1×10-4 kmol/m3, cIAA,Sf,ex=0.22-2.58×10-3 kmol/m3, EF,ex=90.0-97.9%, KD,ex=9.0-46.6, and ER,ex=66.5-94.2%. It was found that cIAA,F0 had the most significant positive effect on cIAA,Ff and cIAA,Sf, whereas cNaOH,S0 had a major positive effect on EF, KD, and ER. A deterministic model based on mass transfer of IAA was developed and its parameters, i.e., mass transfer coefficient of IAA-L complex in the liquid membrane (0.08-1.15×10-6 m/s) and extraction constant (1033.9-1779.7 m3/kmol), were regressed from experimental data. The effect of cL,M0 on both parameters was significant.
Radiomics Derived Brain Age Predicts Functional Outcome After Acute Ischemic Stroke
Authors: Bretzner Martin , Bonkhoff Anna , Schirmer Markus , Hong Sungmin , Dalca Adrian , Donahue Kathleen , Giese Anne-Katrin , Etherton Mark , Rist Pamela , Nardin Marco , Regenhardt Robert , Leclerc Xavier , Lopes Renaud , Gautherot Morgan , Wang Clinton , Benavente Oscar , Cole John , Donatti Amanda , Griessenauer Christoph , Heitsch Laura , Holmegaard Lukas , Jood Katharina , Jiménez-Conde Jordi , Kittner Steven , Lemmens Robin , Levi Christopher , McArdle Patrick , McDonough Caitrin , Meschia James , Phuah Chia-Ling , Rolfs Arndt , Ropele Stefan , Rosand Jonathan , Roquer Jaume , Rundek Tatjana , Sacco Ralph , Schmidt Reinhold , Sharma Pankaj , Slowik Agnieszka , Sousa Alessandro Viana Oliveira e , Stanne Tara , Strbian Daniel , Tatlisumak Turgut , Thijs Vincent , Vagal Achala , Wasselius Johan , Woo Daniel , Wu Ona , Zand Ramin , Worrall Bradford B. , Maguire Jane , Lindgren Arne , Jern Christina , Golland Polina , Kuchcinski Grégory , Rost Natalia 
Published: September 2021

Abstract
While chronological age is one of the most influential determinants of post-stroke outcomes, little is known of the impact of neuroimaging-derived biological brain age. We here first examine whether radiomics analysis of the texture of brain T2-FLAIR MRI images can be used to predict brain age in stroke patients. We then assess the clinical determinants of accelerated brain aging and, finally, its impact on post-stroke functional outcomes. Leveraging a multisite cohort of 4,163 ischemic stroke patients, we show that older-appearing patients have more hypertension, diabetes mellitus, prior strokes, and smoking history and are more likely to develop worse post-stroke outcomes than their younger-appearing counterparts. Our results strengthen the importance of preventive medicine for maintaining brain health in stroke patients as they age and suggest a novel methodology to capture previously undescribed prognostic information available on commonly acquired MRI sequences during routine stroke care.
Low-Profile Visualized Intraluminal Support Stent for the Endovascular Treatment of Traumatic Internal Carotid Artery Pseudoaneurysms
Authors: Tan Song , Zhou Xiaobing , Lu Yuzhao , Lai Lingfeng , Huang Xiaofei , Li Bin , Wang Yang 
Published: September 2021

Abstract
Objectives Optimal treatment strategies for traumatic internal carotid artery (ICA) pseudoaneurysms are controversial. The low-profile visualized intraluminal support (LVIS) device is a braided stent with a metal coverage rate between traditional laser cut stents and flow diversion devices. We report here our therapy strategy using the LVIS stent-assisted coiling for treatment of traumatic ICA pseudoaneurysms.Methods Patients with traumatic ICA pseudoaneurysms treated by the LVIS stent-assisted coiling in our center between January 2015 to June 2021 were reviewed. The complications, radiographic, and clinical outcomes of these patients were analyzed.Results A total of 12 pseudoaneurysms in 12 patients were included. Immediate postoperative angiogram showed that six (50%) aneurysms were Raymond grade 1, four (33.3%) were grade 2, and two (16.7%) were grade 3. Two patients with severe primary cranial injury discontinued treatment after the procedure. During the follow-up of the other ten patients, two patients (20%) received additional coiling because of recanalization of the pseudoaneurysm. At the last angiographic follow-up examination, all aneurysms were Raymond grade 1. Postoperative multiple cerebral infarction occurred in two patients. Of the ten patients with a mean clinical follow-up of 32.2 ± 27.9 (median, 18) months, eight patients recovered well, one patient had right hemiplegia, and one patient died of airway damage, which was unrelated to the pseudoaneurysm.Conclusions LVIS stent-assisted coiling was a feasible approach for the treatment of traumatic ICA pseudoaneurysms.
Anticoagulant therapy in elderly patients with atrial fibrillation : A time series study using the nationwide claim database in Japan
Authors: Tsuji Noriko , TAKAHASHI Yoshimitsu , Sakai Michi , Ohtera Shosuke , Kaneyama Junji , Cho Kosai , KATO Genta , Ohtsuru Shigeru , Nakayama Takeo 
Published: September 2021

Abstract
Background and aim: The introduction of direct oral anticoagulants (DOACs) has greatly changed the use of anticoagulant therapy in patients with non-valvular atrial fibrillation (Af). However, few studies have reported on the current state of anticoagulant therapy at the national level. This study aimed to examine changes in the proportions of oral anticoagulant (OAC) prescriptions (4 DOACs and a vitamin K antagonist: VKA) in patients with non-valvular Af aged ≥65 years, taking into consideration the risk of cerebral infarction and bleeding.Methods: Anticoagulant prescriptions in outpatients with Af were temporally analyzed using the nationwide claims database in Japan. The proportion of anticoagulants prescribed to Af patients aged ≥65 years was determined. Trends in anticoagulant prescriptions were examined according to cerebral infarction and bleeding risk.Results: The proportion of anticoagulant prescriptions for 12,076 Af patients aged ≥65 years in Japan increased from 41% in 2011 to 56% in 2015. The proportion of prescriptions for DOACs surpassed that of VKA. An increase in DOAC prescriptions was accompanied by an increase in the proportion of anticoagulant prescriptions in each group according to the CHA2DS2-VASc and HAS-BLED scores. The proportion of anticoagulant prescriptions for patients with a high risk of developing cerebral infarction and bleeding showed a marked increase.Conclusion: Trends in anticoagulant prescriptions in patients with non-valvular AfAf in Japan showed a marked increase in DOAC prescriptions. The widespread use of DOACs greatly changes the profiles of cerebral infarction and bleeding risks, which are related to the prescription of anticoagulant therapy in patients with non-valvular Af.
Influence of phosphorus fertiliser blend on grain yield, nutrient concentration, and profitability of soyabean in the Southern Guinea Savanna of Ghana
Authors: Adjei-Nsiah Samuel , Ahiakpa John Kojo , Gyan Kwesi , Kanampiu Fred 
Published: September 2021

Abstract
We conducted on-farm trials in the southern Guinea Savanna of Ghana in 2016 and 2017 to evaluate soyabean response to three fertiliser blends to guide farmers towards profitable adoption of appropriate phosphorus (P) fertiliser blend for improved soyabean production. Old YARA Legume (OYL), New YARA Legume (NYL) and Triple Superphosphate (TSP) fertiliser blends were evaluated. In both years, the P fertiliser blends were evaluated in a Randomised Complete Block Design with 20, 30, and 40 kg P ha-1 application rates together with control. P fertiliser application increased soyabean yields by 1070 kg ha-1. In 2016, fertiliser blend use efficiency (BUE) ranged from 2.9 kg grain per kg fertiliser blend applied with the NYL applied at 40 kg P ha-1 to 7.4 kg grain per kg fertiliser blend applied with the TSP applied at 40 kg P ha-1 with significant differences between treatments. In 2017, BUE ranged from 2.5 kg grain per kg fertiliser blend applied with OYL applied at 40 kg P ha-1 to 9.2 kg grain per kg fertiliser blend applied with the TSP applied at 40 kg P ha-1 with significant differences between treatments. However, P use efficiency did not significantly differ between the different treatments both in the 2016 and 2017 trials. In both 2016 and 2017 trials, the highest benefit cost ratio was attained at the lowest application rate for all the three fertiliser blends suggesting the need to review the current application rate of 30 kg P fertiliser ha-1 promoted in northern Ghana. Furthermore, the provision of credit and/or subsidy for farmers by the government is required to enable uptake and utilisation of fertilisers by farmers.
Successful Therapy on Patients with Yolksac and Embrional Carcinoma by Surgery and Chemotherapy
Authors: Prasetya Fahmi Adhi , Djajalaksana Susanthy , Retnani Diah Prabawati , Isharanto Artono , Normahayu Indrastuti , Okta Shinta 
Published: September 2021

Background: Malignant mixed germ cell tumors account for 13-25% of all non seminoma germ cell tumors, almost all cases were found in males (85%), increased in the third decade, and had an average survival rate of 40-45%. With modern management the average 5-year survival rate can be over 80%.Case Report: We reported a case report in Saiful Anwar Malang Hospital, Indonesia, a young man, 26 years old with an malignant epithelial tumor derived from mediastinal or lung. The CT scan of the chest showed an lobulated solid mass of iso-hipodens on the anterior superior mediastinum, mass encompassing the aortic arch, left pulmonalis artery, subclavian artery. The result from transthoracic FNAB with USG guidance showed an malignant epithelial tumor derived from mediastinal or lung, impression of an adeno squamous carcinoma. The AFP, LDH, and NSE serum level was elevated. Patient underwent a surgical sternotomy and tumor debulking. The biopsy showed an malignant mixed germ cell tumor (yolksac and embrional carcinoma). These were confirming the diagnosis of malignant mixed germ cell mediastinal tumor (yolksac and embrinonal carcinoma). Patient received a combination bleomycin, etoposid, cisplatin 3 series chemoteraphy Â and evaluated.Conclusion: Some procedures like biopsy, tumor marker, could differentiate the subtype of mediastinal germ cell tumor. The multimodality treatment by combining surgical therapy (surgical sternotomy and tumor debulking) with chemotherapy could increase the survival rate of patients.
Active Annotation in Evaluating the Credibility of Web-Based Medical Information: Guidelines for Creating Training Data Sets for Machine Learning
Authors: Nabożny Aleksandra , Balcerzak Bartłomiej , Wierzbicki Adam , Morzy Mikołaj , Chlabicz Małgorzata 
Published: September 2021

Background
The spread of false medical information on the web is rapidly accelerating. Establishing the credibility of web-based medical information has become a pressing necessity. Machine learning offers a solution that, when properly deployed, can be an effective tool in fighting medical misinformation on the web.

Objective
The aim of this study is to present a comprehensive framework for designing and curating machine learning training data sets for web-based medical information credibility assessment. We show how to construct the annotation process. Our main objective is to support researchers from the medical and computer science communities. We offer guidelines on the preparation of data sets for machine learning models that can fight medical misinformation.

Methods
We begin by providing the annotation protocol for medical experts involved in medical sentence credibility evaluation. The protocol is based on a qualitative study of our experimental data. To address the problem of insufficient initial labels, we propose a preprocessing pipeline for the batch of sentences to be assessed. It consists of representation learning, clustering, and reranking. We call this process active annotation.

Results
We collected more than 10,000 annotations of statements related to selected medical subjects (psychiatry, cholesterol, autism, antibiotics, vaccines, steroids, birth methods, and food allergy testing) for less than US $7000 by employing 9 highly qualified annotators (certified medical professionals), and we release this data set to the general public. We developed an active annotation framework for more efficient annotation of noncredible medical statements. The application of qualitative analysis resulted in a better annotation protocol for our future efforts in data set creation.

Conclusions
The results of the qualitative analysis support our claims of the efficacy of the presented method.
Seedling Diversity Considerably Changes Near Localities in Three Salinity Zones of Sundarbans Mangrove Forest, Bangladesh
Authors: Helal Siddiqui ASM , Rahman Md. Masudur , Pitol Md. Najmus Sayadat , Islam Md. Akramul , Hasan Sk Md. Mehedi 
Published: September 2021

The status of natural seedlings near localities in the Sundarbans Mangrove Forest was assessed through a stratified random sampling method to observe seedling composition and diversity, importance value index, family importance value, and species evenness. A total of 63 sample plots of 3,990 m2 area were surveyed in three natural and anthropogenic influenced salinity zones of Sundarbans. A total of 16,166 seedlings of 15 species under 12 families were found. Family Euphorbiaceae showed the highest (59.59%) family relative density and Rhizophoraceae presented the highest (20%) family relative diversity Index (FRDI). The maximum family importance value (FIV) showed by Euphorbiaceae (66.26) and the maximum importance value index (IVI) of species has been observed in Excoecaria agallocha (114.74). Excoecaria agallocha showed the highest relative density (59.6%) and relative abundance (39.87%) where the highest relative frequency (15.27%) was observed by Heritiera fomes. The mean stem density and species diversity index in the whole survey area was 2701 stem ha-1 and 0.0009 correspondingly. The Shannon-Wienner's diversity index was 1.52 where the maximum Shannon-Wienner's diversity index was 2.708. The Simpson's diversity index and Dominance of Simpson index were 0.38 and 0.62 with Simpson's reciprocal index 2.632. The Species evenness index, Menhinick’s, and Margalef's indices were 0.561, 0.118, and 1.445 respectively. The Species diversity index of the three salinity zones were 0.0017, 0.0029, and 0.0035 respectively. The Shannon-Wienner's diversity index of Low Salinity Zone (LSZ), Moderate Salinity Zone (MSZ), and Strong Salinity Zone (SSZ) were 0.887, 1.369, and 1.845 correspondingly where LSZ (0.632) showed the highest Simpson's diversity index follow ed by MSZ (0.394) and SSZ (0.21). The Species evenness index for LSZ, MSZ, and SSZ were 0.346, 0.505, and 0.742 where Menhinick’s Index were 0.148, 0.210, and 0.207 respectively. The analysis showed poor diversity indices and the area was dominated by few species with few families. The status is also reduced with increasing salinity.
EKSPLORASI DAN PERBANYAKAN JAMUR TRICHODERMA SP. SEBAGAI BAHAN PEMBUATAN FUNGISIDA HAYATI DI DESA WATAS
Authors: Saleh Ahmad , Novia Nisa Salsabila  
Published: September 2021

The high intensity of plant disease due to pathogenic fungi in Watas Village makes the use of synthetic fungicides a common way to overcome this problem. Improper use of synthetic fungicides can be a long-term hazard, especially if used continuously. The Integrated Pest Management (IPM) program initiated by the government calls for the use of synthetic fungicides as a last resort and is recommended to use other types of fungicides such as biological fungicides. The fungus Trichoderma sp. is one of the microorganisms that can be used as a biological fungicide by the people of Watas Village. Community education and training programs on how to explore, propagate and manufacture biological fungicides from the fungus Trichoderma sp. then carried out in Watas Village with the farmer groups. The work program carried out by the University of Lampung Community Service Period I students in 2021 aims to provide insights to farmers in Watas Village about how to independently produce biological fungicides as a safe and appropriate solution to controlling plant diseases towards a sustainable agricultural system. Watas Village Farmers are very enthusiastic about participating in this program and hope to apply it in the cultivation process.

Keywords: Biological Fungicide, Trichoderma sp., Integrated Pest Management
MEMBANGKITKAN EKONOMI KELOMPOK WANITA TANI (KWT) OKRA DESA SUKANEGERI DENGAN PEMBUATAN SABUN CUCI PIRING
Authors: Wahyu rahmatulloh et al.  , Dian Risma Puteri  , Fika Yunita Sari  , Vega Nurmalita Sari  , Wahyu Dwi Amansyah  
Published: September 2021

Kelompok Wanita Tani (KWT) OKRA adalah sebuah organisasi masyarakat yang ada didesa Sukanegeri Kecamatan Bangunrejo Kabupaten Lampung Tengah. Dimana para anggotanya adalah masyarakat sekitar yang memiliki keinginan untuk mewujudkan tujuan bersama. Tujuan didirikannya KWT OKRA adalah untuk mengembangkan keterampilan terutama pada sektor pertanian dan sektor ekonomi kreatif masyarakat. Pada salah satu pelaksanaan Program Kerja Kuliah Kerja Nyata(KKN) Universitas Lampung Periode 1 Tahun 2021 di Desa Sukanegeri Kecamatan Bangunrejo Kabupaten Lampung Tengah adalah sosialisasi sekaligus pembuatan Sabun cuci piring guna meningkatkan keterampilan warga dan juga meningkatkan aksesibilitas warga terhadap sabun cuci piring. Sabun cuci piring merupakan kebutuhan skunder dimana sabun cuci piring selalu dibutuhkan setiap saat untuk semua kalangan masyarakat. Maka dari itu Pembuatan sabun cuci piring adalah satu produksi yang dapat membangkitkan ekonomi KWT OKRA Desa Sukanegeri.

Kata kunci: kwt okra, sabun cuci piring, ekonomi