bluuebunny/crossref_metadata_2025_split huggingface dataset:
C-reactive protein and ground-glass opacity as predictors for intractable interstitial lung disease in patients with systemic sclerosis under cyclophosphamide treatment regardless of concomitant glucocorticoids
Authors: Yoshida Yusuke , Sugimoto Tomohiro , Hosokawa Yohei , Suma Harumichi , Kobayashi Hiroki , Ishitoku Michinori , Kohno Hiroki , Tokunaga Tadahiro , Watanabe Hirofumi , Mokuda Sho , Nojima Takaki , Hirata Shintaro , Sugiyama Eiji 
Published: March 2021

Abstract

Objectives
Cyclophosphamide (CYC) has been proposed as a standard induction regimen for interstitial lung disease (ILD) associated with systemic sclerosis (SSc). However, there remain patients with SSc-ILD who are intractable to the therapy. This study aimed to identify factors associated with inadequate response to CYC and investigate how to treat SSc-ILD, especially in the need for glucocorticoids (GCs) combined with CYC.

Methods
This retrospective study included consecutive patients diagnosed with SSc-ILD and treated with CYC between 2009 and 2020. Logistic regression models were used to determine the prognostic factors indicating significant progression of ILD (SP-ILD). The clinical findings of patients treated with vs. without GCs were compared.

Results
Nineteen patients were registered, with a median age of 61.0 years. Fifteen were females, and five were classified into SP-ILD. Baseline high C-reactive protein (CRP) levels and non-widespread or localized ground-glass opacities (GGOs) predicted SP-ILD in multivariable analyses, and the cut-off level of CRP was 0.41 mg/dL. In clinical courses, SSc-ILD with high inflammation temporarily responded to CYC, regardless of the combined use of GCs; however, the therapeutic effects deteriorated soon after stopping CYC.

Conclusion
High CRP levels with non-widespread GGO predicted progressive ILD in patients with SSc treated with CYC.
The remarkable characteristics of the children with colchicine-resistant familial Mediterranean fever in Turkey
Authors: Sahin Nihal , Ozdemir Cicek Sumeyra , Pac Kisaarslan Aysenur , Poyrazoglu Muammer Hakan , Gunduz Zubeyde , Dusunsel Ruhan 
Published: March 2021

Abstract

Objectives
Colchicine is the fundamental treatment of familial Mediterranean fever (FMF). Still, 5–10% of patients are not in remission with colchicine treatment. A consensus could not be established for the definition of colchicine resistance in FMF. This study aimed to determine factors that help to predict colchicine resistance in pediatric FMF patients.

Methods
Patients with FMF that age of diagnosis was under 18 years old were included in our study. Fifty colchicine responsive and 33 colchicine-resistant patients were stratified as groups 1 and 2, respectively. Patients’ clinical and laboratory findings were evaluated. Logistic regression analysis was used to determine the risk factors of colchicine-resistant FMF. Receiver operating characteristic (ROC) curve analysis was used to identify and compare the predictive performances of colchicine-resistant FMF models.

Results
Homozygous exon 10 MEFV mutations were frequent in group 2 (Group 1: 34 (68%), group 2: 32 (97%), p = .013). Univariate analysis showed that the age of onset of symptoms, age of diagnosis, chronic arthritis, myalgia and diarrhea during attacks, and the number of attacks, high ISSF and Pras score, high C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) values under colchicine treatment were risk factors for colchicine-resistant FMF. With multivariate analysis, the number of attacks (OR 1.418, CI (95%) 1.149–1.750, p = .001) and high ESR values (OR 1.129, CI (95%) 1.059–1.204, p&lt;.001) were detected as independent risk factors for colchicine-resistant FMF.

Conclusion
The predictive factors were determined for pediatric colchicine-resistant FMF in our study. The results will help to early diagnosis and treatment of chronic inflammation in FMF.
Structural design of cobalt phosphate on nickel foam for electrocatalytic oxygen evolution
Authors: Zhu Chunfeng , Yu Zhongyuan , Lin Tong , Li Jintang , Luo Xuetao 
Published: April 2021

Abstract
The elaborate design and synthesis of low-cost, efficient and stable electrocatalysts for the oxygen evolution reaction (OER), which may alleviate the current energy shortage and environment pollution, is still a great challenge. Herein, metal phosphonate precursors with controllable morphologies were synthesized in situ on the surface of nickel foam with different solvents, and could be easily converted into carbon- and nitrogen-doped cobalt phosphate through a calcination method. The OER catalytic performance of the final products was studied in detail. The results showed that the nanowire shaped samples of CoPiNF-800 synthesized with deionized water under hydrothermal conditions had the strongest electrochemical performance. They exhibited extraordinary catalytic activity with a very low overpotential of 222 mV at 100 mA cm−2, the smallest impedance and excellent electrochemical stability. These results not only demonstrate the possibility of preparing low-cost OER catalysts based on transition metal phosphate, but also aid our understanding of the controllable synthesis process of different morphologies.
High-resolution satellite-derived river network map reveals small Arctic river hydrography
Authors: Lu Xin , Yang Kang , Bennett Mia M , Liu Chang , Mao Wei , Li Ya , Zhang Wensong , Li Manchun 
Published: April 2021

Abstract
Small rivers (width <30 m) are crucial components of Arctic terrestrial river networks. Yet to date, spatial resolution limitations of commonly used satellite imagery have inhibited quantification of their hydrography. By merging newly available Sentinel-2 multispectral satellite imagery with 2-m ArcticDEM digital elevation data, we created a continuous actively-flowing river network map of the Colville (Kuukpik) River Basin (∼36 000 km2) in Alaska, which includes small rivers as narrow as 10 m. We quantified the river hydrography (stream order and river width, length,surface area, velocity, slope, sinuosity, and catchment area) of the Colville river network in detail, revealing the dominant role of small rivers. Our results show that: (1) small rivers occupy >80% of total river length and surface area of the Colville river network and drain >90% of the catchment area; (2) including numerous small rivers increases the peak of hillslope-channel travel time distribution (TTD) by ∼4 times and shortens the mean hillslope-channel travel time by at least an order of magnitude compared to coarser-resolution river hydrography products; and (3) 87% of the Colville River Basin’s carbon dioxide is emitted from small rivers. In sum, we show that small Arctic rivers greatly influence streamflow TTD and carbon cycle. These findings expand our understanding of Arctic river hydrography to a 10-m spatial resolution and raise prospects for tracking dynamic surface water processes with high-resolution satellite observations.
Vector partition functions and Kronecker coefficients
Authors: Mishna Marni , Rosas Mercedes , Sundaram Sheila 
Published: April 2021

Abstract
The Kronecker coefficients are the structure constants for the restriction of irreducible representations of the general linear group GL(nm) into irreducibles for the subgroup GL(n) × GL(m). In this work we study the quasipolynomial nature of the Kronecker function using elementary tools from polyhedral geometry. We write the Kronecker function in terms of coefficients of a vector partition function. This allows us to define a new family of coefficients, the atomic Kronecker coefficients. Our derivation is explicit and self-contained, and gives a new exact formula and an upper bound for the Kronecker coefficients in the first nontrivial case.
The diversity of macroalgae epiphytes on the thallus surface of Kappaphycus Spp in Serewe Bay, East Lombok
Authors: Ghazali M , Kurnianingsih R , Suryadi B F , Menip  , Widoretno W , Retnaningdyah C , Arumingtyas E L 
Published: April 2021

Abstract

Kappaphycus spp are seaweed that is widely cultivated by coastal communities. The community grows Kappaphycus spp because it has economically profitable. Although Seaweed cultivation often experienced failures caused by environmental, herbivorous, and epiphytic factors. This study aims to determine what type of epiphytes grow on the surface of the thallus Kappaphycus spp. Sampling was conducted at the seaweed cultivation location in Serewe Bay, East Lombok. The sampling stations were determined using the purposive sampling method. Data is displayed as a tabular form and analyzed descriptively. A total of 21 epiphytic species were found in K. alvarezii and K. striatum, namely Ulva compressa, Chaetomorpha crassa, Hypnea sp, H. valentiae, H. saidana, H. pannosa, Spyridia hypnoides, S. filamentosa, Heterosipnonia japonica, H. crispella, Ceramium cingulatum, Ceramium flaccidum, Antithamnionella breviramosa, C. clarionensis, Acantophora spicifera, Bostrichia tenella, Polisiphonia sp., Polisiphonia foetidissima, Tolypiocladia glomerulata, Wrangelia gordoniae, W. tanegana., One species is found only in Kappaphycus alvarezii namely Padina minor. Five species are found only in K. striatum, namely Dictyota mayae, Ceramium cimbricum, Laurencia papillosa, Amphiroa sp.
C. cimbricum is one species that found in two culture method. All environmental parameters are optimal, except for the brightness and water flow in the bottom culture method.
Ear disease determination on computer-assisted outer and middle ear images
Authors: Kadriyan H , Wijaya I G P S , Yudhanto D , Yuliyani E A , Mulyana H 
Published: April 2021

Abstract
This paper proposes a method to determine the outer and middle ear disease from image files in computer data efficiently and developed the environment friendly unit. The proposed method starts its method by analyzing the accessed file. If a file is labeled as a file that needs to be classified, the proposed method collects the list of image files in the directory, then it starts to run CNN-based classification to determine the type of ear disease suffered by the patient based on the information contained in the input image. If an image file is detected as a certain outer and middle ear disease, that file will be given a label and its probability. The CNN engine work for classifying the input image captured by Endoscope Ear Cleaning Tool Kit. The classification machine was developed using 1800 images for 18 disease classes with each class having a sample of 100 to 105 sample images. The sample image was augmented from 900 patient data. The experimental result shows that the Ear Disease Determination on Computer-Assisted Outer and Middle Ear Images which is based on CNN has run properly which is indicated by 80% accuracy and potentially implemented for the rural health center facility.
Effects of mycorrhiza biofertilizer and additive intercropping with peanut on growth, bulb formation, N and P contents of several varieties of shallot
Authors: Wangiyana W , Jaya I K D , Sunarpi  
Published: April 2021

Abstract
Application of mycorrhiza biofertilizer to rice intercropped with soybean could increase growth and yield of rice. This study aimed to examine the effects of mycorrhiza biofertilizer application and intercropping with peanut relay-planted between double-rows of shallot on growth, N and P content, and harvest bulb number of several shallot varieties. The experiment was designed according to Split Split-Plot Design, testing three treatment factors, i.e. intercropping with peanut as the main plots (I0= without, I1= with intercropping), application of mycorrhiza biofertilizer as the sub-plots (M0= without, M1= with mycorrhiza application), and shallot varieties as the sub-sub-plots (V1= Bima Brebes, V2= Ketamonca, V3= Super Phillip). Results indicated that among the three treatment factors, mycorrhiza biofertilizer showed the most significant effects whereas intercropping did not show any significant effects. However, there were two-way interaction effects on some variables, and three-way interaction effect on harvest bulb number, with the highest average (12.8 bulb/clump) was on intercropped “Ketamonca” supplied with mycorrhiza biofertilizer whereas the lowest average (8.7 bulb/clump) was on monocropped “Bima Brebes” without mycorrhiza biofertilizer. Leaf N and P contents were also highest on peanut-intercropped shallot plants supplied with mycorrhiza biofertilizer, indicating the environmentally-friendly nature of using these treatments in increasing shallot productivity.
Good agricultural and postharvest handling practices of Cocoa pods in Lombok to meet Cocoa bean quality for the global market
Authors: Zainuri  , Sjah T , Prameswari N , Werdiningsih W , Tarmizi and 
Published: April 2021

Abstract
Despite being the third-largest cocoa export country globally, the quality of cocoa beans produced in Indonesia, including in West Nusa Tenggara, is low. This paper presents the critical role of good agricultural and postharvest handling practices on local cocoa beans’ quality. This paper’s source of information was obtained from the survey, laboratory trials, and secondary sources. Supporting information was also obtained through reviews of related literature. Good agricultural practice with no chemical application to support sustainable agriculture and postharvest handling practices to produce cocoa pods and cocoa beans that meet the international quality standard is critical. Postharvest handling of the pods, which covered the fresh cocoa beans’ fermentation process, produced a significantly better flavor of the dried cocoa beans. However, these practices have not yet been adopted by farmers in Lombok. Price incentives for the fermented beans may not be promising at the farmer’s level. Another reason is related to the fermentation technology itself, which is not appropriate for small-scale farmers’ conditions. Innovative technology for applying fermentation on the cocoa pods is essential to enhance the technology’s adaption by cocoa farmers.
Impact of Revegetation of Rhizopora apiculata and Rhizopora stylosa on The Development of Mangrove Vegetation in Teluk Jor, East Lombok
Authors: Didik S , Zulhalifah  , Abdul S 
Published: April 2021

Abstract
Mangrove degradation has become a source of awareness, especially the government, such as the Indonesian government. This study aims to assess the effect of planting Rhizopora apiculata and Rhizopora stylosa on the growth and development of mangrove species diversity that grows naturally in Teluk Jor, East Lombok. Methods of data collection using the method of observation and transects. Furthermore, the first data were analyzed using descriptive statistics, and the second was the importance of value index analysis and Shannon-Wiener (H ’) analysis. In this study, five new species were found besides Rhizoproa apiculata and Rhizoproa stylosa. The new species are Avicennia marina, Ceriops tagal, Lumnitzera racemosa, Sonneratia alba, and Sonneratia casidaris. Furthermore, the highest index of importance was Sonneratia alba (tree 239.26, sapling 136.57, and seedling 66.89), and the lowest was Lumnitzera racemosa. Meanwhile, the diversity index is in the medium category, namely 1,451. In this case, the revegetation of two mangrove species in the study location significantly impacts mangrove vegetation growth and development. Therefore, the mangrove revegetation model in Teluk Jor can reference mangrove conservation in other areas.
The policy regime and shift of emissions trading scheme by Australian Labor Party and Emissions Reduction Fund by the coalition in Australia year 2013-2018
Authors: Zihniah Namirah 
Published: April 2021

Abstract
Emissions reduction policies for pollutant companies in Australia has become one issue that divides society and parliament. This study discusses the causes of the shifting of the Emissions Trading Scheme (ETS), a carbon pricing policy by the Australian Labor Party to the Emissions Reduction Fund (ERF) by the Coalition. This study used the political exchange concept by Bruno Dente which describes a mutually beneficial relationship between the Coalition (consisting of the Liberal Party and National Party) with business groups. In addition, Carter A. Wilson’s theory of policy regimes and policy regime change was used to see the presence of interest groups and stages in policy shifts. This study used a qualitative approach by collecting data from literature studies and the Australian institution’s website, Hansard. Based on the findings, political exchange between the Coalition and business groups encourages the creation of conditions where stressors / enablers, legitimacy crisis, and power shifts occur. The Coalition as opposition then weakens the ETS policy regime by the reigning Australian Labor Party (ALP). After the Coalition won the election, there was an ETS policy shift by ALP to become an ERF which passed through the House of Representatives and Senate, and was approved by Governor General in 2014.
Effects of climate change on dryland agriculture vegetation index in Nangapanda, East Nusa Tenggara
Authors: Buditama Gilang , Saiya Halvina G , Putri Nadya P 
Published: April 2021

Abstract
Dryland agriculture produces agricultural commodities in the food and plantation sectors. However, the potential for dryland agriculture in Indonesia is one of the agricultural bases, which is also threatened by climate anomalies. This research aims to examine one of the climatic factors, namely Land Surface Temperature (LST), which is influenced by environmental carrying capacity factors, namely the vegetation index on the productivity of dryland agriculture. The vegetation indexes used are NDVI, SAVI, and EVI, using Landsat 5 TM and Landsat 8 OLI imagery for 1999, 2004, 2009, 2014, and 2019 then analyzed by statistical regression tests. Another data used are temperature comparison data from the Meteorological Climatological and Geophysical Agency of Indonesia as known as Badan Meteorologi Klimatologi dan Geofisika (BMKG), agricultural productivity data from Statistics Indonesia as known as Badan Pusat Statistik (BPS), and Agricultural Counseling Agency of Nangapanda District as known as Badan Penyuluhan Pertanian (BPP). The result obtained from this research is that there is a significant inverse relationship between the vegetation index and LST. Later, the increase in LST can cause a decrease in the productivity of dryland agriculture.
Towards a low carbon solid waste management in West Papua
Authors: Prabawardani Saraswati , Hendri  , Karuniasa Mahawan , Syamsudin Kati , Maharani Cynthia , Munichputranto Fajar 
Published: April 2021

Abstract
Solid waste is one of the main contributors to greenhouse gas (GHG) emissions. With an increasing population and Gross Domestic Regional Product (GDRP) of West Papua at 2.65% and 5.2% per annum, solid waste production will also be increased and GHG emissions. However, a specific amount of GHG emission in West Papua was yet to be determined due to the unavailability of solid waste generation across all districts within West Papua. This paper aims to assess solid waste generation by using a dynamic model system that involved total population and GDRP across West Papua as the main variables to measure the data above. This paper shows that 2 (two) scenarios to simulate the business as usual (BAU) process of existing waste management and proposed scenarios to reduce GHG emissions at a convenient level. Based on the BAU model, West Papua will produce 3.7 million tons of waste and 1.1 million tons CO2e in 2030. The proposed scenario suggests that West Papua should manage their waste of up to 118.297 tons/year to meet the NDC 29% emission reduction target. These models could be replicated to solve the same issues in different areas.
Acceleration for disasters: Evaluation of the disaster management act in Indonesia
Authors: Ayuni Qurattu , Arsil Fitra 
Published: April 2021

Abstract
This paper discusses disaster law evaluation in Indonesia after enacting Law Number 24 of 2007 concerning Disaster Management (Disaster Management Act). Several issues, such as the affirmation of the central and regional government’s authority, the role of Disaster Management Agency, and the accountability of emergency funds, are noteworthy to reform the Disaster Management Act in Indonesia. The methodology is legal, library-based research focusing mainly on primary and secondary sources. This paper argues that the amendment to the Disaster Management Act’s urgency is crucial to respond to some accelerations after a decade of the Disaster Management Act. Completing the Disaster Management Act is expected to be a comprehensive legal umbrella in guaranteeing citizens’ constitutional rights and duty when a disaster is in Indonesia.
Life cycle assessment of powder milk production in Indonesia
Authors: Silalahi Ursula C , Gozan Misri , Chairani Ellyna 
Published: April 2021

Abstract
The industry is a human activity established to process resources or materials into goods or products that humans can utilize. The dairy processing industry is one of the industries that process raw milk into various products, such as milk powder. The process of dairy processing industry activities not only produces a product but also contributes to environmental impacts. The main objective of this research determines the most potential environmental impact caused by the production process. The research will be conducted on milk powder products manufactured by PT X. The products chosen in this research are a product with a size of 40 grams per-sachet (product A) and product with a size of 200 grams per-sachet (Product B). The LCA research boundary is “gate to gate,” such as materials transportation from supplier, manufacturing process and management waste. The method used to determine the potential environmental impacts is life cycle assessment (LCA) method. Software SimaPro v.9.1 calculates the impact assessment. The calculations showed potential environmental impacts on product A and product B, such as Marine Ecotoxicity, Freshwater Ecotoxicity, and Human Toxicity. Based on the process stages of product A and product B, the potential environmental impact arises from the manufacturing process.
Adat law and culture: The local authority elements of Baduy tribe on environment preservation
Authors: Asteria Donna , Brotosusilo Agus , Soedrajad M R , Nugraha F N 
Published: April 2021

Abstract
Indonesia is a country that has cultural diversity and Adat law, one of which is the culture of the Baduy tribe. However, social and economic changes that impact the environment led researchers to identify how the Baduy tribe maintains an environment based on cultural and adat laws. This paper used observation and interview methods to identify the environmental preservation that the Baduy tribe has been doing. Baduy Luar has used modern goods, but Baduy Dalam still does not use it. Both do not cut down trees in protected forest areas and still rely on the river to meet their daily water needs, from farming, drinking, or only bathing and cleaning the furniture. They believe and trust “ancestral rules”. That beliefs make them trust to Pu’un as someone with authority, which always preserves that ancestral rules. Pu’un can decide on preserved their ancestral rule. These are fundamental aspects as the laws here represent how the culture tries to reserve the environment. That is much needed as the laws will not do it anymore to prevent environmental damage by society. However, this paper results can be used to build the culture and law for preserved the environment in national society with further study.