bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scientific and Methodological Approaches to Creating a System of Pedagogical Diagnostics of the Level of Training and Development of Primary School Graduates
Authors: Kuznetsova M. , Vinogradova Natalya 
Published: August 2021

The article discusses the problem of obtaining reliable information about the level of educational achievements of junior schoolchildren during
their transition to the next stage of school education. The implementation of the development goals of students at the initial stage of schooling, set by the Federal State Educational Standard of Primary General Education, requires pedagogical diagnostics, which makes it possible to establish the cause of the difficulties that children have in the course of studying various subjects. This ensures the timely intervention of the teacher in the learning process to provide each younger student with pedagogical assistance and support, which makes it possible to eliminate the individual difficulties that arise in him.
Personalized Priority Policies in Call Centers Using Past Customer Interaction Information
Authors: Hathaway Brett Alan , Emadi Seyed Morteza , Deshpande Vinayak 
Published: August 2021

To increase revenue or improve customer service, companies are increasingly personalizing their product or service offerings based on their customers' history of interactions. In this paper, we show how call centers can improve customer service by implementing personalized priority policies. Under personalized priority policies, managers use customer contact history to predict individual-level caller abandonment and redialing behavior and prioritize them based on these predictions to improve operational performance. We provide a framework for how companies can use individual-level customer history data to capture the idiosyncratic preferences and beliefs that impact caller abandonment and redialing behavior and quantify the improvements to operational performance of these policies by applying our framework using caller history data from a real-world call center. We achieve this by formulating a structural model that uses a Bayesian learning framework to capture how callers’ past waiting times and abandonment/redialing decisions affect their current abandonment and redialing behavior and use our data to impute the callers’ underlying primitives such as their rewards for service, waiting costs, and redialing costs. These primitives allow us to simulate caller behavior under a variety of personalized priority policies and hence, collect relevant operational performance measures. We find that, relative to the first-come, first-served policy, our proposed personalized priority policies have the potential to decrease average waiting times by up to 29% or increase system throughput by reducing the percentage of service requests lost to abandonment by up to 6.3%. This paper was accepted by Vishaul Gaur, operations management.
Implementing Environmental and Social Responsibility Programs in Supply Networks Through Multiunit Bilateral Negotiation
Authors: Feng Qi , Li Chengzhang , Lu Mengshi , Shanthikumar J. George 
Published: August 2021

Involving suppliers deep in the supply chain is critical for the success of environmental and social responsibility (ESR) initiatives. Administering ESR programs throughout a complex supply network, however, is challenging. In this paper, we apply a multiunit bilateral bargaining framework to coordinate ESR investments in a general supply network and analyze to what extent an ESR initiator should directly engage the higher-tier suppliers as opposed to delegating that responsibility to the first-tier suppliers. Our bargaining framework not only generalizes the conventional Shapley value approach by allowing the flexibility of modeling imbalanced power distribution among the firms but also provides an explicit way of implementing the resulting gain sharing among the firms through negotiated contract terms. We show that the eventual structure of ESR negotiation relationships can be derived by finding a shortest path tree in the supply network with the arc cost defined as the logarithm of the negotiating parties’ relative bargaining power. These developments allow us to analyze ESR implementation in generally extended supply networks. We find that the ESR initiator tends to delegate ESR negotiations to a supplier that is strong in negotiations with higher-tier suppliers. When the supply network is complex (i.e., wide and deep), directly engaging all suppliers can lead to a larger gain by the initiator than fully delegating the negotiations with higher-tier suppliers to the first-tier ones. However, as the network gets increasingly complex, the ESR initiator tends to directly engage a reduced percentage of higher-tier suppliers. We further extend our analysis to situations where the ESR relationships are sequentially formed in a decentralized manner, where the benefit of ESR depends on the collective choice of the firms’ investment levels, where multiple ESR programs are implemented in the network, and where ESR investments depend on the negotiation relationships.This paper was accepted by David Simchi-Levi, operations management.
Optimal Auction Duration: A Price Formation Viewpoint
Authors: Paul Jusselin , Thibaut Mastrolia , Mathieu Rosenbaum 
Published: August 2021

Optimal Auction Duration in Financial Markets In the considered auction market, market makers fill the order book during a given time period while some other investors send market orders. The clearing price is set to maximize the exchanged volume at the clearing time according to the supply and demand of each market participant. The error made between this clearing price and the efficient price is derived as a function of the auction duration. We study the impact of the behavior of market takers on this error to minimize their transaction costs. We compute the optimal duration of the auctions for 77 stocks traded on Euronext and compare the quality of the price formation process under this optimal value to the case of a continuous limit order book. Continuous limit order books are usually found to be suboptimal. Order of magnitude of optimal auction durations is from 2–10 minutes.
Laser-driven resonant magnetic soft-x-ray scattering for probing ultrafast antiferromagnetic and structural dynamics
Authors: Schick Daniel , Borchert Martin , Braenzel Julia , Stiel Holger , Tümmler Johannes , Bürgler Daniel E. , Firsov Alexander , von Korff Schmising Clemens , Pfau Bastian , Eisebitt Stefan 
Published: August 2021

Time-resolved resonant magnetic scattering in the soft-x-ray range is a powerful tool for accessing the spatially resolved and element-specific spin dynamics in magnetic materials. So far, the application of this photon-demanding technique was limited to large-scale facilities. However, upgrades to diffraction-limited storage rings supporting only x-ray pulses beyond 100 ps, and the shift of x-ray free-electron lasers toward attosecond pulses aggravate the competition for beamtime in the picosecond time window, which is of utmost relevance for magnetism research. Here we present the development of a lab-based instrument providing sufficient photon flux up to 1.5 keV photon energy covering the soft-x-ray resonances of transition and rare-earth metal atoms. Our setup features the mandatory tunability in energy and reciprocal space in combination with sub-10 ps temporal resolution, exploiting the broadband emission of a laser-driven plasma x-ray source, which is monochromatized to about 1 eV bandwidth by a reflection zone plate. We benchmark our approach against accelerator-based soft-x-ray sources by simultaneously probing the laser-induced magnetic and structural dynamics from an antiferromagnetically coupled Fe/Cr superlattice. Our development lays the foundation for laser-driven resonant scattering experiments to study ultrafast ordering phenomena of charges, spins, and orbitals.
Availability, affordability and stock-outs of commodities for the treatment of snakebite in Kenya
Authors: Ooms Gaby Isabelle , van Oirschot Janneke , Okemo Dorothy , Waldmann Benjamin , Erulu Eugene , Mantel-Teeuwisse Aukje K , van den Ham Hendrika A , Reed Tim 
Published: August 2021

Background
Annually, about 2.7 million snakebite envenomings occur globally. Alongside antivenom, patients usually require additional care to treat envenoming symptoms and antivenom side effects. Efforts are underway to improve snakebite care, but evidence from the ground to inform this is scarce. This study, therefore, investigated the availability, affordability, and stock-outs of antivenom and commodities for supportive snakebite care in health facilities across Kenya.

Methodology/principal findings
This study used an adaptation of the standardised World Health Organization (WHO)/Health Action International methodology. Data on commodity availability, prices and stock-outs were collected in July-August 2020 from public (n = 85), private (n = 36), and private not-for-profit (n = 12) facilities in Kenya. Stock-outs were measured retrospectively for a twelve-month period, enabling a comparison of a pre-COVID-19 period to stock-outs during COVID-19. Affordability was calculated using the wage of a lowest-paid government worker (LPGW) and the impoverishment approach. Accessibility was assessed combining the WHO availability target (≥80%) and LPGW affordability (<1 day’s wage) measures. Overall availability of snakebite commodities was low (43.0%). Antivenom was available at 44.7% of public- and 19.4% of private facilities. Stock-outs of any snakebite commodity were common in the public- (18.6%) and private (11.7%) sectors, and had worsened during COVID-19 (10.6% versus 17.0% public sector, 8.4% versus 11.7% private sector). Affordability was not an issue in the public sector, while in the private sector the median cost of one vial of antivenom was 14.4 days’ wage for an LPGW. Five commodities in the public sector and two in the private sector were deemed accessible.

Conclusions
Access to snakebite care is problematic in Kenya and seemed to have worsened during COVID-19. To improve access, efforts should focus on ensuring availability at both lower- and higher-level facilities, and improving the supply chain to reduce stock-outs. Including antivenom into Universal Health Coverage benefits packages would further facilitate accessibility.
Active rheumatoid arthritis in a mouse model is not an independent risk factor for periprosthetic joint infection
Authors: Trikha Rishi , Greig Danielle , Sekimura Troy , Cevallos Nicolas , Kelley Benjamin , Mamouei Zeinab , Hart Christopher , Ralston Micah , Turkmani Amr , Sassoon Adam , Stavrakis Alexandra , Bernthal Nicholas M. 
Published: August 2021

Introduction
Periprosthetic joint infection (PJI) represents a devastating complication of total joint arthroplasty associated with significant morbidity and mortality. Literature suggests a possible higher incidence of periprosthetic joint infection (PJI) in patients with rheumatoid arthritis (RA). There is, however, no consensus on this purported risk nor a well-defined mechanism. This study investigates how collagen-induced arthritis (CIA), a validated animal model of RA, impacts infectious burden in a well-established model of PJI.

Methods
Control mice were compared against CIA mice. Whole blood samples were collected to quantify systemic IgG levels via ELISA. Ex vivo respiratory burst function was measured via dihydrorhodamine assay. Ex vivo Staphylococcus aureus Xen36 burden was measured directly via colony forming unit (CFU) counts and crystal violet assay to assess biofilm formation. In vivo, surgical placement of a titanium implant through the knee joint and inoculation with S. aureus Xen36 was performed. Bacterial burden was then quantified by longitudinal bioluminescent imaging.

Results
Mice with CIA demonstrated significantly higher levels of systemic IgG compared with control mice (p = 0.003). Ex vivo, there was no significant difference in respiratory burst function (p = 0.89) or S. aureus bacterial burden as measured by CFU counts (p = 0.91) and crystal violet assay (p = 0.96). In vivo, no significant difference in bacterial bioluminescence between groups was found at all postoperative time points. CFU counts of both the implant and the peri-implant tissue were not significantly different between groups (p = 0.82 and 0.80, respectively).

Conclusion
This study demonstrated no significant difference in S. aureus infectious burden between mice with CIA and control mice. These results suggest that untreated, active RA may not represent a significant intrinsic risk factor for PJI, however further mechanistic translational and clinical studies are warranted.
Quantitative measurement of the histological features of alpha-1 antitrypsin deficiency-associated liver disease in biopsy specimens
Authors: Marek George , Collinsworth Amy , Liu Chen , Brantly Mark , Clark Virginia 
Published: August 2021

Background
Pathological mutations in Alpha-1 Antitrypsin (AAT) protein cause retention of toxic polymers in the hepatocyte endoplasmic reticulum. The risk for cirrhosis in AAT deficiency is likely directly related to retention of these polymers within the liver. Polymers are classically identified on liver biopsy as inclusion bodies by periodic acid schiff staining after diastase treatment and immunohistochemistry. However, characterization of the polymer burden within a biopsy sample is limited to a semi-quantitative scale as described by a pathologist. Better methods to quantify polymer are needed to advance our understanding of pathogenesis of disease. Therefore, we developed a method to quantify polymer aggregation from standard histologic specimens. In addition, we sought to understand the relationship of polymer burden and other histologic findings to the presence of liver fibrosis.

Methods
Liver samples from a well-categorized AATD cohort were used to develop histo-morphometric tools to measure protein aggregation.

Results
Whole-slide morphometry reliably quantifies aggregates in AATD individuals. Despite very low levels of inclusions present (0–0.41%), accumulation of globules is not linear and is associated with higher fibrosis stages. Immunohistochemistry demonstrates that fibrosis is associated with polymer accumulation and not total AAT. A proportion of patients were found to be “heavy accumulators” with a polymer burden above the upper 25% of normal distribution. Males had significantly more liver inclusions and polymer than females. These measurements also highlight interrelated phenotypes of hepatocellular degeneration and autophagy in AATD liver disease.

Conclusion
Quantitative inclusion analysis measures AAT accumulation in liver biopsy specimens. Quantification of polymer may identify individuals at risk for progressive disease and candidates for therapeutic interventions. Furthermore, these methods may be useful for evaluating efficacy of drugs targeting accumulation of AAT.
A case of effective use of interleukin 6 inhibitors in patients with ankylosing spondylitis with secondary amyloidosis
Authors: Erdes Sh. F. , Rumyantseva D. G. , Agafonova E. M. , Urumova M. M. , Starkova A. S. , Krasnenko S. O. 
Published: August 2021

Ineffectiveness of interleukin 6 inhibitors (iIL6), tocilizumab (TCZ) and sarilimumab in ankylosing spondylitis (AS) was shown in randomized clinical trials. However, there is ample evidence that IL6 is actively involved in the pathogenesis of this disease. In addition, the efficacy of iIL6 in patients with secondary AA-amyloidosis was established.Objective: to analyze the results of TCZ administration in AS, complicated by secondary AA-amyloidosis.Patients and methods. The analysis included 6 patients with AS with secondary AA-amyloidosis. All patients were HLA-B27 positive male. The average age of patients was 44±9.2 years, the average age of the disease onset was 16.3±7.9 years, the average duration of AS was 26.0±7.5 years. All 6 patients had pathomorphologic confirmed secondary AA-amyloidosis: all had kidney affection, 5 patients also had gastrointestinal tract affection and 2 had heart affection. As a first biological drug TCZ was prescribed in 2 patients, and 4 patients had previously received one or more inhibitors of tumor necrosis factor α. The average duration of TCZ treatment was 27.6 [3.0; 36.0] months.Results and discussion. During TCZ therapy, the level of CRP (M±σ) significantly decreased: from 81.1±74.5 to 1.2±0.8 mg/L (p<0.05), as well as daily proteinuria (Me [25th ; 75th percentile]): from 1.8 [1.0; 2.1] to 0.2 [0.1; 0.3] g/day (p<0.05) and AS activity indices – BASDAI (M±σ): from 6.2±1.6 to 3.3±0.9 (p<0.05 ); ASDAS-CRP (M±σ) from 4.6±1.1 to 2.04±0.7 (p<0.05). Positive dynamics was also noted in relation to a decrease in the number of patients with inflammatory back pain, arthritis and coxitis. A case of clinical and laboratory remission of AS on TCZ treatment is described. Conclusion. The presented data show that in certain clinical situations iIL6 can be highly effective in AS.
Metallurgical Failure Investigation of Fractured Spring Seals
Authors: Neidel A. , Cagliyan E. , Fischer B. 
Published: August 2021

Abstract
Elastic sealing elements used in combustion chamber assemblies of heavy-duty gas turbine engines used for power generation fractured from high cycle fatigue failure. The subject assembly was burner rig tested in a special testing facility. It was speculated that the affected spring seals likely failed due to forced excitation during burner rig testing, since no material imperfections or fabrication flaws, such as spot weld imperfections, were detected that could have contributed to the failure.
English L3 acquisition in heritage contexts: Modelling a path through the bilingualism controversy
Authors: Lorenz Eliane , Toprak Tugba Elif , Siemund Peter 
Published: August 2021

Abstract
The current study adds to research investigating the influence of bilingualism on third language (L3) acquisition, more specifically the assumption that the two previously acquired languages enhance the acquisition of an additional language. We here rely on data from 1,409 bilingual (Russian-/Turkish-German) and monolingual (German) students of grades seven and nine, sampled in schools across Germany. The relevant literature yields mixed and controversial results regarding bilingual advantages, yet it also suggests that L3 acquisition is a multidimensional process potentially affected by various linguistic and extra-linguistic factors. Thus, we examine the relationship between English proficiency (L2 or L3), reading comprehension in German and the heritage languages Turkish and Russian along with cognitive ability and socio-economic status by using several multi-group path analyses, a type of structural equation modelling. The proposed structural equation model of English proficiency can be successfully fitted for all participants investigated, i.e. for both the monolingual and bilingual learners, with the exception of the Turkish-German group when analyzed separately. Overall, the results do not suggest any obvious bilingual facilitation effects or general differences across the learner groups, yet minor differences between the monolingual and bilingual groups in various componential relationships are detected.
The effect of focus and the focus particlesamoon the exclusion of contextual alternatives in Serbian
Authors: Živković Ema , Sudimac Nina 
Published: August 2021

AbstractThe goal of this paper is to investigate the relationship between focus and the inferences that listeners derive from utterances. While the function of focus is to generate a set of alternatives to the focused element, it can also evoke the implicature that the statement does not hold for the contextual alternatives, which is referred to as exhaustive meaning. Whether focus is exhaustive is a matter of cross-linguistic variation. This paper aims to assess exhaustive inferences in Serbian triggered by focus in situ marked by prosodic prominence and in the preverbal position, canonical sentences with neutral intonation, and the exclusive particlesamo‘only’. The participants were presented with the recorded test items, after which they were asked to express their judgement about the possibility of the contextual alternatives using a scale. The results indicated that there was no interpretative difference regarding exhaustive meaning between the sentences with the focused words marked with prosodic prominence and those with unmarked intonation. However, the sentences with the preverbal focused target word were judged as significantly more exhaustive than the canonical sentences with default intonation. Finally, the sentences with the focus particlesamowere interpreted mostly as not allowing other contextual interpretations.
Begrenzt dezentral gesteuerte Produktion – modelliert im Swimmingpool-Modell
Authors: Lonsdorfer Maxime , Scheunemann Merle , Maßmann Melanie , Gärtner Henner 
Published: August 2021

Abstract
Das Institut für Produkt- und Produktionsmanagement der HAW Hamburg forscht an der geeigneten Modellierung dezentraler Steuerungskonzepte für die Produktion zum Zwecke praxistauglicher Implementierungen. Zunächst wird der Einfluss der Entwicklung digitaler Technologien auf die historische Entwicklung klargestellt. Darauf aufbauend wird dargelegt, wie die HAW Hamburg ein so genanntes „Swimmingpool-Modell“ als Grundstein für die Forschung an dezentralen Steuerungskonzepten aufbaut und validiert.
Kompensation thermo-elastischer Maschinenfehler
Authors: Brecher Christian , Fey Marcel , Wittmann Marcel , Dehn Mathias 
Published: August 2021

Abstract
Die Nachfrage nach präziseren Werkzeugmaschinen steigt kontinuierlich. Aus diesem Grund müssen thermo-elastische Fehlerkompensationsmethoden unter thermischen Echtzeitbedingungen genauer werden. Die korrekte Parametrierung eines modellbasierten Korrekturansatzes für die Kompensation thermo-elastischer Maschinenfehler hat einen maßgeblichen Einfluss auf die Modellgenauigkeit. Insbesondere für die Langzeitkompensation der Maschinenfehler benötigt das Modell eine hohe Anpassungsfähigkeit aufgrund variierender Lasten. In diesem Beitrag wird eine Simulationsmodellarchitektur vorgestellt, die ein FEM-basiertes thermo-elastisches White-Box-Modell der Werkzeugmaschine mit Temperaturmessungen der Maschinenstruktur kombiniert. Die Messdaten der Temperatursensoren werden für eine prozessparallele Anpassung thermischer Modellparameter genutzt, um die Genauigkeit der Kompensationsmethode zu steigern.
Erprobung anwendungsadaptierter CVD-Diamantschichten beim Stanzen
Authors: Winter Sven , Stein Christian , Richter Karsten , Höfer Markus , Sittinger Volker , Psyk Verena , Kräusel Verena 
Published: August 2021

Abstract
CVD-Diamantschichten werden aktuell bei der spanenden Bearbeitung herausfordernder Werkstoffe eingesetzt und führen zu einer deutlichen Erhöhung der Standzeiten. Insbesondere nanokristalline Diamantschichten ermöglichen geringe Rauheiten bei gleichzeitig höchsten Härten. In der vorliegenden Studie wurden diese Schichten erstmals auf Hartmetall-Schneidstempel für das Stanzen von federharten Bändern appliziert und ihr Einfluss auf den Verschleiß untersucht. Untersuchungen mit Hubzahlen von bis zu 100.000 haben für Schichtdicken im Bereich von 8 μm sehr gute Ergebnisse gezeigt. Derartige Nano-Diamantschichten besitzen folglich großes Potenzial zur Reduzierung des Verschleißes von Hartmetallstempeln in Stanzprozessen.