bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peer influence in adolescent drinking behavior: A meta-analysis of stochastic actor-based modeling studies
Authors: Ivaniushina Valeria , Titkova Vera 
Published: April 2021

Objectives
To measure the effects of peer influence and peer selection on drinking behavior in adolescence through a rigorous statistical approach designed to unravel these interrelated processes.

Methods
We conducted systematic searches of electronic databases, thesis collections and conference proceedings to identify studies that used longitudinal network design and stochastic actor-oriented modeling to analyze drinking behavior in adolescents. Parameter estimates collected from individual studies were analyzed using multilevel random-effects models.

Results
We identified 26 articles eligible for meta-analysis. Meta-analyses for different specifications of the peer influence effect were conducted separately. The peer influence effect was positive for every specification: for average similarity (avSim) mean log odds ratio was 1.27 with 95% confidence interval [0.04; 2.49]; for total similarity (totSim) 0.46 (95% CI = [0.44; 0.48]), and for average alter (avAlt) 0.70 (95% CI = [-0.01; 1.41]). The peer selection effect (simX) was also positive: 0.46 (95% CI = [0.28; 0.63]). Conversion log odds ratio values to Cohen’s d gives estimates from 0.25 to 0.70, which is considered as medium to large effect.

Conclusions
Advances in methodology for social network analysis have made it possible to accurately estimate peer influence effects free from peer selection effects. More research is necessary to clarify the roles of age, gender, and individual susceptibility on the changing behavior of adolescents under the influence of their peers. Understanding the effects of peer influence should inform practitioners and policy makers to design and deliver more effective prevention programs.
Cesión de fármacos desde liposomas en distintos medios biorrelevantes
Authors: Toro Azahara I. , De Jesús Valle María José 
Published: April 2021

Los liposomas constituyen sistemas vesiculares ideales para la liberación controlada y vectorización de fármacos a través de su administración pulmonar, debido a su similitud con las membranas celulares y su gran versatilidad.
El citrato de sildenafilo, representa un óptimo modelo de fármaco para ser incorporado en estas vesículas lipídicas para el tratamiento de la hipertensión pulmonar.
El objetivo del trabajo fue caracterizar el comportamiento de los liposomas cargados con sildenafilo y evaluar la cesión del fármaco en distintos medios biorrelevantes.
Se elaboraron liposomas de dos tamaños (0.45 y 0.20 micras) mediante sonicación. Posteriormente se llevó a cabo el ensayo de liberación del fármaco en diferentes medios biorrelevantes (fluido plasmático simulado SBF, fluido pulmonar simulado SPF y PBS).
Según los resultados obtenidos se observó una velocidad de liberación del fármaco más sostenida y constante a lo largo del tiempo en el caso de los liposomas, independientemente del medio. En los medios PBS y SPF, se liberó una mayor cantidad de fármaco desde los liposomas con mayor tamaño (0,45 µm), sin embargo, en el SBF las cinéticas de cesión de ambos tamaños de liposomas (0,45 y 0,20 µm) son muy similares, no encontrándose diferencias significativas en el tiempo o cantidad de fármaco liberada.
Supervivencia de los niños con Leucemia Linfoide Aguda manejados con protocolo Basado en ALL-IC-BFM 2009 en Bogotá D.C. Colombia.
Authors: Ozaeta Daniel , Casallas Alexander , Martínez Leila , Castillo Angélica , Baquero Olga , Cobos Olga 
Published: April 2021

Introducción: La Leucemia Linfoide Aguda es la neoplasia más frecuente en la infancia y por ello, la estrategia de tratamiento y el acceso a cada una de las intervenciones son aspectos definitorios en la curación del paciente. Objetivos: determinar la supervivencia global y libre de evento de pacientes con Leucemia Linfoide Aguda tratados con estrategia basada en el protocolo Leucemia Linfoide Aguda Intercontinental Berlín Frankfurt y Münster (ALL-IC-BFM 2009) contando con un programa de seguimiento administrativo permanente al cual ingresa el paciente una vez se le realiza el diagnostico oncológico. Al igual que establecer la supervivencia de los pacientes según el grupo de riesgo asignado y describir la tasa de recaída en el grupo evaluado. Métodos: se siguieron por 4 años 51 pacientes menores de 18 años con diagnóstico de Leucemia Linfoide Aguda, tratados con la estrategia ALL-IC-BFM 2009 que entraron al programa de atención integral del paciente oncológico de la Clínica Infantil Colsubsidio. Estudio observacional de cohorte prospectiva con análisis de supervivencia. Resultados: La supervivencia global para la cohorte a 4 años fue del 71.1 %, mientras que la supervivencia libre de evento fue del 69.4 %. La supervivencia global según los grupos de riesgo fue del 89 %, para el riesgo estándar de 85.2 %, para el grupo de riesgo intermedio y de 39.8 % para el grupo de riesgo alto. Conclusiones: La supervivencia global se comportó como la reportada en la región, sin embargo, los resultados obtenidos en los pacientes de riesgo estándar e intermedio superaron la supervivencia global.
جرائم السيبرانية المرتكبة عبر الوسائط الرقمية
Authors: العتيبي أ. زياد بن محمد عادي 
Published: April 2021

تناولت هذه الورقة مفهوم الجرائم السيبرانية وبيان أشكالها،خصائصها، أركانها ودوافعها، حيث أدى تطور تقنية المعلومات في القرن العشرين إلى ظهور أشكال جديدة و مستحدثة من الجرائم التي لم تعتاد عليها البشرية وأصبح الفضاء السيبراني مسرحاً لها، حيث يستطيع المجرم من خلال هذا الفضاء تمرير هجماته بشكل سريع وخفي ولا يترك في الغالب أثر لجريمته حتى أصبح من المصعب على المحققين والمختصين اكتشاف أو إثبات الجريمة؛ لأنها ارتكبت في مسرح افتراضي غير ملموس ولا حدود له وأصبحت الأدلة التقليدية غير قادرة على إثبات هذه الجرائم ولا تستطيع مجاراتها ، وبالتالي يُصعب إدانة المتهم الأمر الذي أدى إلى ظهور تساؤل عن ماهية الجرائم السيبرانية، أشكالها ،خصائصها، أركانها، ودوافعها وحيث أن التحول الرقمي أحد الركائز الأساسية لتحقيق رؤية المملكة 2030 لتنمية البنية التحتية الرقمية ، ونظراً لأهميتها فقد ناقش البحث مفهوم الجرائم السيبرانية من حيث أشكالها ،خصائصها، أركانها، ودوافعها ، وقد توصلت الدراسة إلى العديد من النتائج والتوصيات أبرزها بأن المجرم السيبراني يستغل الأزمات وأن من أبرز أساليب التصيد الإلكتروني خلال هذه الفترة من الدراسة وما تشهده البلاد في مواجهة جائحة كورونا هي التصيد بإسم كورونا(COVID-19)،وكذلك ضرورة تدخل المشرع في اصدار نظام خاص ومستقل بالإجراءات الجزائية الرقمية بما يواكب التحول الرقمي الذي تشهده المملكة.
Notes sur le phénomène érotique
Authors: Henry Michel 
Published: April 2021

Cet article présente des notes préparatoires inédites de Michel Henry sur le phénomène érotique. Ces notes sont essentiellement relatives à la préparation des ouvrages « Philosophie et phénoménologie du corps » et « L’essence de la manifestation », mais également et plus tardivement de son livre « Incarnation ». Maine de Biran est au cœur de ce projet, mais Michel Henry lit et commente également ses contemporains, dont Sartre qui est sans doute celui qui reçoit le plus d’attention de sa part.
Le concept henryen de « réalité ». Sur le sens du noème, de l’objet et de l’étant dans la phénoménologie matérielle.
Authors: Lheureux Julien 
Published: April 2021

Cette étude propose d’étudier le concept de réalité, dans le cadre de l’élaboration d’une philosophie première et d’une philosophie qui entend thématiser les modes de la révélation. La voie prise est, en quelque sorte, celle « par la négative », puisque J. Lheureux part d’une enquête sur le rôle du noème et sur le sens de l’irréalité (donc sur le plan de l’extériorité et de sa déréalisation) chez M. Henry — perspective profondément originale. L’analyse des déplacements que M. Henry opère par rapport à Husserl et son enquête sur l’idée est particulièrement fine et montre comment le refus husserlien de l’objectivisme est repris et rejoué dans la compréhension henryenne de la réalité, au gré d’un « procédé d’idéalisation de l’être transcendant » qui vise à « faire refluer le tout de la réalité dans l’auto-apparaître de la Vie ».
La question de « l’autre langage »
Authors: Leclercq Jean 
Published: April 2021

C’est sans doute en estimant que « l’histoire de l’existence du Christ a un sens phénoménologique fondamental » que Michel Henry cautionne son projet de travail sur le christianisme. Cette dimension de son œuvre constitue sans doute une crux interpretandi pour les spécialistes et l’on sait combien elle peut les gêner. De fait, les interrogations sont nombreuses : quand Henry parle du christianisme, est-il resté phénoménologue, s’agit-il même tout simplement encore d’une philosophie et, corollairement, est-il justifiable au gré des œuvres de la Raison de penser de la sorte les rapports historiques complexes entre ce que nous disons être le philosophique et le théologique ? Ce sont ces questions qu’il faut au moins poser sereinement dans le cadre de ce travail d’édition des notes préparatoires que nous proposons ici et où il est évident que s’y cherche un support de réflexion sur cet « autre » du langage dont Henry cherche ultimement à comprendre la provenance.
Michel Henry et l’humanisme marxien.
Authors: Haber Stéphane 
Published: April 2021

S. Haber tente de montrer combien le projet de relire l’œuvre de Marx au prisme d’une réévaluation philosophique, en elle-même justifiée et féconde, des descriptions « phénoménologiques » de la souffrance sociale, le conduit non seulement à entériner, même s’il en inverse la téléologie, l’idée althussérienne d’une coupure épistémologique dans l’œuvre de Marx, mais aussi à interpréter différemment, pour cette raison même, les deux« moments » de la pensée marxienne et ce qui caractérise la transition de l’un a l’autre : Les manuscrits de 1844 d’abord, dont Henry ne retiendrait que ce qu’ils doivent à Hegel, Le Capital ensuite, dont il méconnaitrait au contraire ce qu’il lui doit encore. C’est l’équation posée entre souffrance sociale/aliénation et praxis subjective qui est ici interrogée, sur l’horizon d’une théorie de l’« organisation collective », basée sur les concepts de « socialité » et de « coopération », minimisant du coup l’opérativité forte du concept phénoménologique de chair.
Ice Cream in the Cathedral: The Literary Failures and Social Success of Chinese Robot Poet Xiao Bing
Authors: Krenz Joanna 
Published: April 2021

Abstract
In May 2017, Xiao Bing, a popular Chinese chatbot built by Microsoft Research Asia, made her debut as a poet with Sunlight Has Lost Its Glass Windows, a collection marketed as the entirely created by artificial intelligence. She learnt the art of poetry by “reading” the works of 519 modern Chinese poets, and her “inspiration” comes from pictures provided first by her programmers and later by netizens, who upload photographs through her website. Xiao Bing’s emergence made a splash in Chinese society and raised grave concerns among the poets, who polemicized with her engineers. This essay traces Xiao Bing’s literary and media career, which includes both notable literary failures and notable commercial success, exploring her complex connections to technologies of power/knowledge as well as cultural phenomena that range from traditional Chinese poetry and poetry education to postmodern camp aesthetics. From within the renegotiation of the nature of poetry at the threshold of the posthuman era, I propose the critical notion of reading-as-playing to help poetry take advantage of its various entanglements and strictures in order to survive and co-shape the brave new world.
Circulating tumor DNA (ctDNA) as a pan-cancer screening test: is it finally on the horizon?
Authors: Duffy Michael J. , Diamandis Eleftherios P. , Crown John 
Published: April 2021

Abstract
The detection of cancer at an early stage while it is curable by surgical resection is widely believed to be one of the most effective strategies for reducing cancer mortality. Hence, the intense interests in the development of a simple pan-cancer screening test. Lack of sensitivity and specificity when combined with the low prevalence of most types of cancer types in the general population limit the use of most of the existing protein biomarkers for this purpose. Like proteins, tumor DNA also can be released into the circulation. Such circulating tumor DNA (ctDNA) can be differentiated from normal cell DNA by the presence of specific genetic alteration such as mutations, copy number changes, altered methylation patterns or being present in different sized fragments. Emerging results with test such as CancerSEEK or GRAIL suggest that the use of ctDNA can detect cancer with specificities >99%. Sensitivity however, is cancer type and stage-dependent, varying from approximately 40% in stage I disease to approximately 80% in stage III disease. It is important to stress however, that most of the studies published to date have used patients with an established diagnosis of cancer while the control population were healthy individuals. Although the emerging results are promising, evidence of clinical utility will require demonstration of reduced mortality following evaluation in a prospective randomized screening trial.
Circulating pro-gastrin releasing peptide (ProGRP) in patients with medullary thyroid carcinoma
Authors: Giovanella Luca , Fontana Martina , Keller Franco , Campenni’ Alfredo , Ceriani Luca , Paone Gaetano 
Published: April 2021

Abstract

Objectives
Serum calcitonin (CT) is pivotal in medullary thyroid cancer (MTC) management. Recently, progastrin releasing peptide (ProGRP) has been proposed as a candidate complementary tumor marker of MTC. As current data are sparse our study was undertaken to evaluate the distribution of ProGRP in patients with MTC and its relationship with the tumor burden. Additionally, serial measurement of CT, carcinoembryonic antigen (CEA) and ProGRP was evaluated in three patients undergoing tyrosine kinase inhibitors (TKI).

Methods
Seventy-eight, 125 and 62 sera from patients with MTC, non-medullary malignant and benign thyroid diseases were collected, respectively. ProGRP measurement was performed by Elecsys® assays on Cobas e601 platform (Roche Diagnostics).

Results
Significantly higher ProGRP levels were found in MTC compared to non-MTC patients. Among MTC patients ProGRP levels accurately discriminate patients with active from those with cured disease and, respectively, patients with loco-regional active disease from those with distant metastasis. Finally, ProGRP performed better than CT and CEA in monitoring the response to TKI therapy in three patients monitored serially.

Conclusions
Serum ProGRP is promising as a complementary tumor marker in MTC patients. Further studies will be required, mainly focused on monitoring ProGRP during TKI treatment for early detection of resistance and assessing its usefulness to avoid the observed false positive fluctuations that occur with CT and carcinoembryonic antigen.
Aroma components of tobacco powder from different producing areas based on gas chromatography ion mobility spectrometry
Authors: Qin Guangjiong , Zhao Guojie , Ouyang Canbin , Liu Jialei 
Published: April 2021

Abstract
Gas chromatography-ion mobility spectrum (GC-IMS) is used to analyze and compare the differences in aroma among different tobacco samples. The aroma substances in tobacco samples in Jilin Changchun are the richest, while those in Guangdong Nanxiong are the lowest. The concentrations of aroma substances such as decanal, 1-hydroxy-2-propanone, and 2-methylbutanol were the highest in Guangdong Nanxiong of the three. The concentration of 1-hexanol, cyclohexanone, pentanoic acid, and other aroma substances in Fujian Nanping was high. The concentration of 2-acetylfuran, 2-octanol, isopentanol, 3-methylvaleric acid, phenylacetic acid, and other aroma substances in Changchun area of Jilin Province was low. Through principal component analysis and similarity research, both tobaccos can be distinguished by their production areas and grades from the same.
Balancing information-structure and semantic constraints on construction choice: building a computational model of passive and passive-like constructions in Mandarin Chinese
Authors: Liu Li , Ambridge Ben 
Published: April 2021

AbstractA central tenet of cognitive linguistics is that adults’ knowledge of language consists of a structured inventory of constructions, including various two-argument constructions such as the active (e.g.,Lizzy rescued John), the passive (e.g.,John was rescued by Lizzy) and “fronting” constructions (e.g.,John was the one Lizzy rescued). But how do speakers choose which construction to use for a particular utterance, given constraints such as discourse/information structure and the semantic fit between verb and construction? The goal of the present study was to build a computational model of this phenomenon for two-argument constructions in Mandarin. First, we conducted a grammaticality judgment study with 60 native speakers which demonstrated that, across 57 verbs, semantic affectedness – as determined by further 16 native speakers – predicted each verb’s relative acceptability in thebei-passive andba-active constructions, but not the Notional Passive and SVO Active constructions. Second, in order to simulate acquisition of these competing constraints, we built a computational model that learns to map from corpus-derived input (information structure + verb semantics + lexical verb identity) to an output representation corresponding to these four constructions (+“other”). The model was able to predict judgments of the relative acceptability of the test verbs in theba-active andbei-passive constructions obtained in Study 1, with model-human correlations in the region ofr = 0.5 andr = 0.3, respectively. Surprisingly, these correlations increased (tor = 0.75 andr = 0.5 respectively) when lexical verb identity was removed; perhaps because this information leads to over-fitting of the training set. These findings suggest the intriguing possibility that acquiring constructions involves forgetting as a mechanism for abstracting across certain fine-grained lexical details and idiosyncrasies.
Tribological characteristics of polymer materials used for slide bearings
Authors: Walczak Mariusz , Caban Jacek 
Published: April 2021

Abstract
The automotive industry uses a variety of technologies and construction materials in production process. Knowledge of the characteristics of tribological material pairs cooperating with each other is useful for their selection from the safety point of view sliding pairs, in means of transport, and other machines. The aim of the contribution is the analysis of the characteristics of tribological ball-on-disc wear of polymeric materials used as sliding bearings. Tribological tests were carried out under dry friction for a polymer–metal pair of three types of materials. Among all three groups of the tested materials statistically significant differences (p < 0.05 in Student’s t-test) in wear were observed. The wear rate and friction coefficient of the sample were tested, and the signs of wear were submitted to SEM observations.
Set-theoretic solutions to the Yang–Baxter equation and generalized semi-braces
Authors: Catino Francesco , Colazzo Ilaria , Stefanelli Paola 
Published: April 2021

AbstractThis paper aims to introduce a construction technique of set-theoretic solutions of the Yang–Baxter equation, calledstrong semilattice of solutions. This technique, inspired by the strong semilattice of semigroups, allows one to obtain new solutions. In particular, this method turns out to be useful to provide non-bijective solutions of finite order. It is well-known that braces, skew braces and semi-braces are closely linked with solutions. Hence, we introduce a generalization of the algebraic structure of semi-braces based on this new construction technique of solutions.
Challenges in management of transient hyperinsulinism – a retrospective analysis of 36 severely affected children
Authors: Hoermann Henrike , Roeper Marcia , Salimi Dafsari Roschan , Koestner Felix , Reinauer Christina , Mayatepek Ertan , Meissner Thomas , Kummer Sebastian 
Published: April 2021

Abstract

Objectives
Transient hyperinsulinism (THI) is a hypoglycemia disorder which resolves spontaneously within the first weeks or months of life. The pathomechanism of THI is not elucidated yet; however, it is known that perinatal stress predisposes for THI. We aimed to characterize the clinical phenotype and treatment of children with THI, and to identify options for improved management.

Methods
A retrospective analysis of 36 children with THI treated at the University Children’s Hospital Düsseldorf between 2007 and 2019 was performed.

Results
All children had risk factors for neonatal hypoglycemia or indicators of perinatal stress. Eighty three percent were diagnosed with hypoglycemia on day of life (DOL)1. None of the six diagnosed later had routine blood glucose screening and showed significantly lower blood glucose levels at the time of first blood glucose measurement compared to the children diagnosed on DOL1. Ninety seven percent of all children received intravenous glucose, 42% received continuous glucagon and 81% were started on diazoxide. Diazoxide withdrawal and subsequent fasting tests lacked standardization and were based on clinical experience. Three patients had a subsequent episode of hypoglycemia, after fasting studies only demonstrated “clinical” remission without proving the ability to ketogenesis.

Conclusions
Any kind of perinatal stress might pose a risk to develop THI, and postnatal monitoring for hypoglycemia still needs to be improved. Diazoxide is effective in children with THI; however, further studies are needed to guide the development of criteria and procedures for the initiation and discontinuation of treatment. Furthermore, establishing consensus diagnostic criteria/definitions for THI would improve comparability between studies.
Research on brightening modification of molecular sieves coated fly ash based on alkaline melting hydrothermal method
Authors: Gao Hangtian , Liu Jianan , Song Helong , Yang Jingkun , Mou Hongyan , Fan Huiming 
Published: April 2021

AbstractImproving the utilization rate of fly ash (FA) and realizing its resource utilization has always been a popular research topic in the application field of solid waste recycling. This paper aims to improve the basic brightness of fly ash (FA) before calcium carbonate coating, and realize the filling application of fly ash in medium and high-end paper. Taking advantage of the high brightness of molecular sieves (MS) (brightness ≥ 90 %ISO), the alkali melting hydrothermal synthesis (AM-HS) method was used to generate high brightness MS on the surface of fly ash. The results showed that the optimum conditions of alkali melting hydrothermal synthesis (AM-HS) modification were as follows: the mass ratio of sodium hydroxide to fly ash was 1:1, the time of hydrothermal modification was 6 h, the temperature of hydrothermal modification was 80 °C, and the brightness reached to 64.54 %ISO; The results of SEM, particle size analysis and ultrasonic vibration showed that the surface of fly ash is covered by MS and has strong binding effect.
A Most Notable Dwelling: The Domus Romana and the Urban Topography of Roman Melite
Authors: Lowe Benedict 
Published: April 2021

Abstract
This paper offers an overview of Roman Melite: the paper examines the epigraphic evidence for the topography of the urban centres of Gaulos and Melite in particular, the activities of wealthy benefactors and the civic government of the municipia through benefactions to the Temples to Apollo and Proserpina and dedications to the Imperial Cult. There is only limited evidence for the buildings themselves apart from the Domus Romana that was discovered on the outskirts of Rabat in 1881. The urban area appears to have been in decline by the fourth century AD despite the presence of a Late Roman see and Byzantine officials. The paper concludes with the abandonment of the island as a consequence of the Aghlabid sack of 870.