bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnostic Utility of BAP1, EZH2 and Survivin in Differentiating Pleural Epithelioid Mesothelioma and Reactive Mesothelial Hyperplasia: Immunohistochemical Study
Authors: Hakim Sarah Adel , Abou Gabal Hoda Hassan 
Published: April 2021

Background: Epithelioid mesothelioma (EM) is the commonest subtype of malignant pleural mesothelioma. Its histopathological discrimination from reactive mesothelial hyperplasia (RMH) could be challenging. Thus, an immunohistochemical panel is mandatory for better discrimination. BAP1 is a newly identified diagnostic marker whose loss is specific to malignant mesothelioma. EZH2 overexpression is reported in different cancers, but its relation to BAP1 in malignant mesothelioma has not been fully understood. Survivin expression is said to be significantly higher in EM than in non-neoplastic pleural tissue, but its diagnostic utility as an immunohistochemical marker has not been thoroughly investigated in this field. To the best of our knowledge, no previous studies have been conducted to assess the diagnostic accuracy of the combined use of these three nuclear markers (BAP1, EZH2 and Survivin) in discriminating pleural EM from RMH.Methods: This retrospective study includes two groups: 81 cases of pleural EM and 67 cases of RMH, retrieved from the archives of Pathology Department of Ain Shams University Hospitals and Ain-Shams University Specialized Hospital during the period from January 2016 to December 2019. An immunohistochemical study was performed using BAP1, EZH2 and Survivin antibodies.Results: There were highly statistically significant relations between study groups as regards the studied markers (p = 0.001 for each). The specificity was 100% for all combinations of immunohistochemical markers. Sensitivity of any combination of the immunohistochemical markers used in this study was found to be higher than the sensitivity of any of these markers used individually. The combination of all three markers showed the highest diagnostic accuracy (95.9%) and the highest sensitivity (92.6%). However, the combination of Survivin and EZH2 yielded the same diagnostic accuracy and sensitivity.Conclusion: Adding EZH2, Survivin and BAP1 to the diagnostic IHC panel for differentiating pleural EM and RMH could enhance diagnostic sensitivity. Moreover, Survivin is a potentially promising marker in this context, especially when combined with EZH2.
MARINE TRAFFIC ON MEDITERRANEAN SEAS AND ITS DIVISIONS
Authors: CHIROSCA Ana-Maria , RUSU Liliana 
Published: April 2021

The Mediterranean Sea is the largest sea in the world and its most important sub-divisions regarding maritime traffic are the Ionian Sea, Tyrrhenian Sea, Ligurian Sea, Balearic Sea, Alboran Sea, Aegean Sea and the Adriatic Sea.
This paper analyses how marine traffic has evolved in this area over the centuries, considering the historical traffic corridors (such as the Adriatic-Ionian Transport Corridor), the climate, the different sea-level rise due to climate change, and the wave heights and its period.
Water circulation on Mediterranean is affected on a short time scale due to weather changes, and especially due to changes in salinity and temperature that could make the sea more stratified by the end of the 21st cen-tury.
Regarding the complex meteorological factors, the high number of islands, islets, narrow passages, canals and submerged rocks in the waters, Mediterranean Sea remains one of the most important shipping routes with significant tanker traffic and unfortunately one of the areas with higher risk of maritime accidents, 75% of the shipping accidents being recorded in Aegean Sea.
Political and legal tradition of the East: the problem of understanding
Authors: Lomakina Irina 
Published: April 2021

The article deals with the complex legal tradition (the tradition of traditions) of the East determining the ways of civilizational development of all non-European peoples being involved in the non-Western cultural ecumene. It is noted that the complex Eastern legal tradition has received an ambiguous assessment in the theoretical and legal discourse. Its various interpretations being repletet with negative connotations are largely associated with ideological preferences stemming from the liberal idea that there is no law in the East, and Eastern despotism has preserved political culture for many years making it an appendage of totalitarian statehood. Ideological cliches are repeated from one textbook to another, they are met in a range of monographs on foreign history and the history of political and legal thought. This article provides an alternative view on the understanding of Eastern statehood with its attributes of “duty”, “responsibility”, “collectivism” having become fundamental staples of the Eastern complex legal tradition. It is noted that the material conditions of social life and the mentality projected on the state-legal life have created a special type of public administration, which contrary to forecasts of an “imminent death”, shows miracles of vitality to this day. The article describes in sufficient detail the Confucian doctrine with its non-legal from the point of view of Western culture methods of education and edification, which in fact became a prologue to the communitarian projects of the future. The article proves that the study of the fundamental provisions of the Eastern tradition makes it possible to question the established narratives that “the past of the West is in the East” and “the East is the resource margin of the advanced world”. The modern world is multi-faceted, so understanding the Eastern complex legal tradition gives reason to better understand yourself through the prism of another. Therefore, the article actualizes the understanding that the Eastern type of legal tradition has an internal logic of development and this type is neither better nor worse than the Western one.
Removal of Mo/Si multilayer coatings on fused silica substrates by wet chemical etching
Authors: Toyoda Mitsunori , Yokoyama Ryo , Waki Shuntaro , Kakudate Toshiyuki , Chen Jun 
Published: April 2021

Abstract
This work examined a novel etching procedure for the complete removal of Mo/Si multilayer coatings, as a means of reusing valuable mirror substrates employed in extreme ultraviolet imaging. A multilayer coating deposited on a fused silica substrate was etched with an alkaline solution containing potassium ferricyanide and sodium hydroxide, and the entire coating was removed within 60 min. The root mean square roughness and power spectrum density characteristics were subsequently assessed and the resulting values were equivalent to those before the deposition of the coating. These results demonstrate that such coatings can be removed while maintaining the original surface figure.
Kinetic progress in post-synthetic doping of 2D perovskite nanoplatelets
Authors: Zhang Ruohu , Qu Junfeng , Chen Zizi , Wang Chunlei , Xu Shuhong 
Published: April 2021

Abstract
Room-temperature post-synthetic doping in perovskite has drawn much attention for its looser condition and controllable doping. Compared with direct synthesis, the kinetic progress in post-synthetic doping is unique and may provide new methods for the manipulation of doping. In this work, the kinetic progress during post-synthetic doping in 2D perovskite nanoplatelets (NPLs) is studied. It was found that in spite of the feeding ratio, the concentration of dopant precursor can also affect post-synthetic doping progress. Afterwards, Mn was doped into 2D perovskite NPLs through fixed-volume doping and fixed-concentration doping for comparison and both methods can realize white-light emission.
Pré-natal na atenção primária, adequação das consultas e avaliação da assistência í s gestantes: revisão integrativa
Authors: de Freitas Moreno Rodrigues Adriene , Lievore Candido Cecí­lia , Palmeira Campos Greice Kelly , Simoura Barcellos José Emí­lio , Rodrigues Luciano Antonio , Seidel Tássia Sabrina 
Published: April 2021

Objetivo: avaliar a assistência í s gestantes na atenção primária í saúde e a adequação das consultas de pré-natal. Método: trata-se de uma revisão integrativa de literatura, descritiva de abordagem qualitativa, realizada no ano de 2019. Utilizou-se artigos da Biblioteca Virtual em Saúde (BVS), através dos seguintes descritores padronizados no DeCS: qualidade da assistência í saúde, cuidado pré-natal e saúde da mulher, resultando em 107 artigos. Após filtragem com os critérios de inclusão/exclusão, seguida de uma leitura criteriosa em resposta ao problema de pesquisa, totalizou numa amostra de 14 artigos. Resultados: destes, onze artigos tiveram em suas conclusões a necessidade de mudanças no acompanhamento pré-natal. Conclusão: a pesquisa possibilitou a visualização das dificuldades relacionadas í gestão, a união da equipe multiprofissional, da capacitação e aperfeiçoamento dos profissionais de saúde, da melhoria das consultas de pré-natal e também da diferença na qualidade da assistência prestada í s mulheres negras e indí­genas.
Глибинне навчання для аудіо-додатків
Authors: Логвін A. 
Published: April 2021

Розкрито принципи застосування глибокого навчання для нейронних мереж щодо розпізнавання аудіо-сигналів. Відокремлено області подання звуку. Підкреслено, що дослідження буде обмежено аудіо-сигналами. Описано принципи розбиття сигналу на складові елементи та їх вилучення із аудіо запису. Наведено схему формування розподілу аудіо-сигналу та запропоновано загальний підхід до задачі розпізнавання аудіо-сигналів. Він умовно поділений на три окремі етапи: обробка аудіо-запису та його перетворення у частотно-часову область, побудова спектрограми та її перетворення на формат з подальшим виведенням послідовності ознак у вигляді векторів. Визначений коефіцієнт накладання та середньозважений коефіцієнт перекриття (частковий збіг). Сформовано низку значень на основі проведеного експерименту, які показали, що на характеристики / параметри аудіо-додатків, сформовані за допомогою нейронної мережі з глибоким навчанням, має вплив метод підготовки даних, додавання шарів та формування спектру одиниць, що покращує результат за рахунок помноженого часу навчання, те саме стосується і періодичних з'єднань.
Estudo Etnobotânico de Plantas Medicinais Utilizadas por alguns Moradores de Três Comunidades Rurais do Município de Cabaceiras do Paraguaçu/Bahia
Authors: Rodrigues Eliete Serra , De Brito Noelma Miranda , De Oliveira Vania Jesus Santos 
Published: April 2021

As pesquisas etnobotânicas envolvem levantamentos nas sociedades tradicionais sobre o uso dos vegetais na farmacopeia caseira, bem como questões culturais e econômicas da população, além das interações do homem com o meio ambiente. A Etnobotânica é o estudo do conhecimento da flora de uma região, que se preocupa com os sujeitos e com os seus saberes, reúne informações dos que mantiveram relações com os vegetais e com elementos culturais de um povo. Objetivou-se realizar um estudo etnobotânico de plantas medicinais utilizadas em três comunidades rurais do município de Cabaceiras do Paraguaçu/BA. Foram aplicados 286 questionários aos membros das comunidades em suas residências. Para a análise dos dados, empregou-se a frequência relativa. Os participantes foram investigados quanto ao perfil socioeconômico e ao uso das plantas medicinais. Foram identificadas 45 espécies medicinais pertencentes a 25 famílias botânicas. As famílias Lamiaceae e Asteraceae foram as duas famílias botânicas mais representativas no estudo etnobotânico. A família Lamiaceae foi a mais representativa em número de espécies utilizadas como medicinais, e as espécies mais citadas foram capim santo (Cymbopogon citratus Stapf.), erva cidreira (Lippia alba L.), boldo (Plectranthus barbatus Andrews) e hortelã (Mentha spicata L.). As plantas são adquiridas nos quintais das casas, usadas na forma de chá ou infuso. As folhas foram as partes da planta mais utilizadas. Evidenciou-se a importância da realização de estudos etnobotânicos como forma de resgatar e evitar a perda dos saberes tradicionais das comunidades de Jacarezinho, Nova Aparecida e Pé de Serra, e a conservação de espécies medicinais da flora da região.
Non-dimensional method of capacity limit states for the assessment of the safety level in the structures of large panel buildings.
Authors: BIERANOWSKI Piotr , BARYŁKA Adam 
Published: April 2021

In the article deals with the European safety issues of large-panel buildings from the point of view of exceeding the ULS. The proprietary assessment method was proposed under the name: Dimensional Limit States Method, which is dedicated to the assessment of the safety level in the structures of large-panel buildings. The work was based on many years of computer research conducted by the author. In the paper uses the proprietary construction model of the Wk-70 system building, presents the results for vertical reinforcement inserts.
Meningkatkan Kemampuan Motorik Halus Anak Melalui Finger Painting Menggunakan Tepung Singkong
Authors: Wahyuni Rizki , Erdiyanti  
Published: April 2021

Penelitian ini bertujuan untuk mengetahui tingkat pencapaian perkembangan motorik halus anak di kelas B Kelompok Bermain Nur’Ain Mola Selatan Kabupaten Wakatobi. Tehnik pengumpulan data yang digunakan adalah observasi, dokumentasi dan penilaian. Sedangkan model yang dipilih untuk melakukan tindakan yaitu siklus model Kemmis dan Mc Taggart yang memiliki empat tahapan yakni perencanaan, tindakan, observasi dan refleksi. Data perkembangan motorik halus anak diperoleh melalui observasi dan dokumentasi selanjutnya dianalisis dengan menggunakan presentase. Penelitian dilakukan dua siklus, setiap siklus dilakukan dua kali pertemuan. Hasil penelitian menunjukkan bahwa finger painting menggunakan tepung singkong dapat meningkatkan perkembangan motorik halus anak kelas B KB Nur’ain Mola Selatan Kabupaten Wakatobi. Hal ini dapat dilihat hasil observasi yang menunjukkan bahwa perkembangan motorik halus anak mengalami perubahan yang sangat baik. Pada pra siklus atau sebelum dilakukan tindakan penelitian anak yang dikatakan tuntas mencapai 23,07%, pada siklus I anak yang tuntas mencapai 61,53% dan pada siklus II anak yang tuntas mencapai 84,61%. Hal ini menunjukkan peningkatan dari penelitian awal sampai siklus II keterampilan motorik halus semakin meningkat dan dapat dikatakan berhasil karena telah sesuai dengan indikator tingkat pencapaian yakni 75%.
Peran Orangtua dalam Pendidikan Anak Usia Dini di Masa Pandemi Covid-19
Authors: Tanjung Rahmadani 
Published: April 2021

Penelitian tindakan ini bertujuan untuk mendiskripsikan peran orang tua dalam implementasi homeschooling pada anak usia dini di masa pandemi covid-19, serta mengetahu hasil belajar yang diperoleh anak melalui homeschooling. Penelitian ini merupakan penelitian kualitatif study kasus. Informann penelitian satu keluarga, dengan Informansi utama orangtua, dan Informann pendukung anak, paman, dan guru. Data diperoleh dengan wawancara dan observasi partisipan pada keluarga. Data kemudian diolah dengan menggunakan analisis tema. Hasil yang didapat diperoleh dari penelitian ini adalah orang tua mengkondisikan lingkungan keluarga sebaik mungkin untuk menunjang pendidikan anak, hal ini dibuktikan dengan diputarkan ayat-ayat Al-Qur’an setiapmalam, orang tua selalu meluangkan waktu untuk anak dan komunikasi yang baik dalam keluarga. Selanjutnya adanya komitmen dan peran aktif orang tua dalam pelaksanaan metode homeschooling anak nusia dini juga memiliki dampak positif untuk kemampuan akademik maupun non akademik anak.
Fitting an Analytic Magnetic Field to a Prestellar Core
Authors: Bino Gianfranco , Basu Shantanu 
Published: April 2021

Abstract
We deploy and demonstrate the capabilities of the magnetic field model developed by Ewertowski & Basu by fitting observed polarimetry data of the prestellar core FeSt 1–457. The analytic hourglass magnetic field function derived directly from Maxwell’s equations yields a central-to-surface magnetic field strength ratio in the equatorial plane, as well as magnetic field directions with relative magnitudes throughout the core. This fit emerges from a comparison of a single plane of the model with the polarization map that results from the integrated properties of the magnetic field and dust throughout the core. Importantly, our fit is independent of any assumed density profile of the core. We check the robustness of the fit by using the POLARIS code to create synthetic polarization maps that result from the integrated scattering and emission properties of the dust grains and their radiative transfer, employing an observationally motivated density profile. We find that the synthetic polarization maps obtained from the model also provide a good fit to the observed polarimetry. Our model fits the striking feature of significant curvature of magnetic field lines in the outer part of FeSt 1–457. Combined with independent column density estimates, we infer that the core of size R
gas has a mildly supercritical mass-to-flux ratio and may have formed through dynamical motions starting from a significantly larger radius R. A breakdown of flux freezing through neutral-ion slip (ambipolar diffusion) could be responsible for effecting such a transition from a large-scale magnetic field structure to a more compact gas structure.
Electron Spectrum for the Prompt Emission of Gamma-Ray Bursts in the Synchrotron Radiation Scenario
Authors: Liu Kuan , Lin Da-Bin , Li Jing , Li Yu-Fei , Lu Rui-Jing , Liang En-Wei 
Published: April 2021

Abstract
Growing evidence indicates that the synchrotron radiation mechanism may be responsible for the prompt emission of gamma-ray bursts (GRBs). In the synchrotron radiation scenario, the electron energy spectrum of the prompt emission is diverse in theoretical works and has not been estimated from observations in a general way (i.e., without specifying a certain physical model for the electron spectrum). In this paper, we creatively propose a method to directly estimate the electron spectrum for the prompt emission, without specifying a certain physical model for the electron spectrum in the synchrotron radiation scenario. In this method, an empirical function (i.e., a four-order Bézier curve jointed with a linear function at high energy) is applied to describe the electron spectrum in log–log coordinates. It is found that our empirical function can well mimic the electron spectra obtained in many numerical calculations or simulations. Then, our method can figure out the electron spectrum for the prompt emission without specifying a model. By employing our method on observations, taking GRB 180720B and GRB 160509A as examples, it is found that the obtained electron spectra are generally different from that in the standard fast-cooling scenario and even a broken power law. Moreover, the morphology of electron spectra in its low-energy regime varies with time in a burst and even in a pulse. Our proposed method provides a valuable way to confront the synchrotron radiation mechanism with observations.
Anxiety impact during COVID-19: a systematic review
Authors: Batista Patricia , Duque Vitor , Luzio-Vaz Ana , Pereira Anabela 
Published: April 2021

Introduction: The COVID-19 epidemic has been causing serious physical, but also psychological effects in society. This systematic review sought to identify studies that describe COVID-19 related anxiety, and to understand the impact of anxiety assessment in defining strategies to be implemented in future studies.
Methodology: This systematic review included cross-sectional studies with no publication year limit. It was performed a systematic search through three databases, namely, PubMed, Science Direct and Web of Science using the descriptors “COVID-19” and “anxiety”. PRISMA criteria reporting of systematic reviews and meta-analyses were applied. Eligible articles were selected in accordance with inclusion and exclusion criteria. The inclusion criteria were: research articles related with anxiety measurement during the COVID-19 outbreak; interventions to reduce anxiety; and published in English.
Results: From 44 references, just four scientific articles were accepted for inclusion within this review. These studies were analyzed regarding their sample, methodology, instruments used, and its results.
Conclusions: This systematic review was based on published data at the onset of the pandemic, and it could serve as a basis for the development of implementations plans to improve anxiety disorders. The importance of this theme, the implications and potential directions for future investigations will be discussed.
Effects of Malaise trap spacing on species richness and composition of terrestrial arthropod bulk samples
Authors: Steinke Dirk , Braukmann Thomas WA , Manerus Laura , Woodhouse Allan , Elbrecht Vasco 
Published: April 2021

The Malaise trap is a popular device for assessing diverse terrestrial arthropod communities because it collects large samples with modest effort. A number of factors influence its collection efficiency, placement being one of them. For instance, when designing larger biotic surveys using arrays of Malaise traps we need to know the optimal distance between individual traps that maximises observable species richness and community composition. We examined the influence of spacing between Malaise traps by metabarcoding samples from two field experiments at a site in Waterloo, Ontario, Canada. For one experiment, we used two trap pairs deployed at weekly increasing distances (3 m increments from 3 to 30 m). The second experiment involved a total of 10 traps set up in a row at 3 m distance intervals for three consecutive weeks.
Results show that community similarity of samples decreases over distance between traps. The amount of species shared between trap pairs drops considerably at about 18 m trap-to-trap distance. This change can be observed across all major taxonomic groups and for two different habitat types (grassland and forest). Large numbers of OTUs found only once within samples cause rather large dissimilarity between distance pairs even at close proximity. This could be caused by a large number of transient species from adjacent habitats which arrive at the trap through passive transport, as well as capture of rare taxa, which end up in different traps by chance.
An Integrative Review of Mentoring Novice Faculty to Teach
Authors: Dahlke Sherry , Raymond Christy , Penconek Tatiana , Swaboda Nicholas 
Published: April 2021

Background:
Novice nursing faculty require support and guidance as they transition from clinical practice to teaching in an academic faculty. Mentoring is an important part of faculty development during the transitional experience. Currently, the learning needs of novice nursing faculty and the effects of formal mentorship programs are not well understood.

Method:
An integrative literature review was conducted from five electronic databases. The articles included in the review described primary research studies focused on formal mentorship programs that supported novice faculty in developing their teaching expertise and identified their learning needs.

Results:
The review yielded eight studies that explored different aspects of the mentoring experience. Socialization to Academia and Navigating Mentorship were two key themes developed from the data.

Conclusion:

Included studies described mentoring programs and a clear need for some type of formalized orientation and mentorship process or program to enhance novice nursing faculty transition to the academic setting and role.

[
J Nurs Educ
. 2021;60(4):203–208.]