bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of 2D Nanoplatelets to Improve The Sensitivity in Hybrid Photodetector For Indirect X-Ray Imaging
Authors: Lee Jehoon , Yoo Kyunghan , Liu Hailiang , Kang Jungwon 
Published: October 2021

Abstract
In this paper, we attempted to improve the detection sensitivity of an indirect X-ray detector through using a hybrid active layer composed of a poly [N-90-heptadecanyl–2,7-carbazole-alt-5,5-(40,70-di-2-thienyl-20,10,30-benzothiadiazole)] (PCDTBT) organic semiconductor and cadmium selenide nanoplatelets (CdSe NPLs) colloidal inorganic semiconductors. First, different blending ratio in the active layer (i.e., 2:1, 1:1, 1:2 and 1:3) of PCDTBT:CdSe NPL were examined, a sensitivity of 0.057 mA/Gy∙cm2 was achieved using a 1:1 ratio due to the low series resistance (RS) and defect density in this configuration. Then, the oleic acid (OA) that was initially applied in the CdSe NPL surface was replaced with pyridine ligands, this was done because the pyridine ligand is a short-chain ligand that can help charge transfer by reducing the distance between NPLs in the active layer. In addition, an experiment was conducted to determine the optimal ligand exchange time. A detector with an PCDTBT:CdSe NPL active layer fabricated using pyridine ligand exchange achieved a sensitivity of 0.14 mA/Gy∙cm2 after an exchange time of 12 hours, this is an improvement of 155% compared to the detector using a PCDTBT:CdSe NPL with the original OA ligands. Lastly, the optimal thickness for the PCDTBT:CdSe NPL active layer was investigated. The highest mobility of 7.60 cm2/V∙s was recorded after fabricating the layer using spin-coating at 1900 rpm, the highest sensitivity of 0.20 mA/Gy∙cm2 was also achieved under these conditions. Compared to the initial state of the detector, our modifications improved the sensitivity of the PCDTBT:CdSe NPL detector by 255%.
Structural, Optical and Electrical Conductivity Studies in Polycarbazole and Its Metal Oxide Nano Composites
Authors: Talari Sankarappa , Raghavendra B. , Malge Amarkumar 
Published: October 2021

Abstract
Polycarbazole (PCz) has been synthesized by chemical oxidation method using APS as an oxidizing agent and PCz/CuO and PCz/Fe2O3 nanocomposites by in situ polymerization method for different wt% of CuO and Fe2O3 at room temperature. XRD patterns confirmed crystalline nature of samples. FTIR indicated strong interaction between PCz and nano fillers. The morphological and optical absorption studies were carried out using SEM and UV-Vis respectively. Addition of CuO or Fe2O3 to PCz decreased its direct and indirect band gaps. However, band gap showed a small change with dopant contents up to 30%. Urbach energy decreased with the addition of dopants. But Urbach energy of the composites increased with increasing dopants content from 10 to 30%. DC conductivity of PCz and its nanocomposites has been measured by following two probe technique in the temperature range from 300 K to 423 K. he conductivity of both the nanocomposites is found to be less than the pure PCz and it is found to increase with wt% of CuO or Fe2O3 as the case may be. The activation energy has been determined by fitting Arrhenius expression to the dc conductivity data at high temperature. The activation energy of polycarbazole is determined to be less than that of the composites. In both the composites, activation energy decreased and conductivity increased with the increase of dopant content.
Neuronal MD2 Induces Long-term Mental Impairments in Septic Mice by Facilitating Necroptosis and Apoptosis
Authors: Fan Zhongmin , Yin Lu , Li Yi , Ma Hongwei , Wu You , Guo Xiaofeng , Du Lixia , Wang Jiajia , Wang Shiquan , Hou Wugang , Dong Hailong , Fang Zongping , Zhang Xijing 
Published: October 2021

Abstract
Sepsis-associated encephalopathy (SAE) is a complication of sepsis that has high morbidity rates. Long-lasting depression is a major mental health disorder in patients with SAE that results in a substantial decrease in quality of life and economic burden. However, the underlying mechanism of SAE is unclear, and effective treatments are not available. In the current study, we explored the role of apoptosis and necroptosis related to depression in sepsis. In a mouse model of cecal ligation and puncture (CLP), we detected mental impairments by the open field test, elevated-plus maze and forced swimming test on the fourteenth day. Moreover, apoptosis- and necroptosis-associated proteins and morphological changes were examined in the hippocampus of the septic mice. These mice showed depression-like behaviors at 14 days after CLP, with substantial increases in neuronal apoptosis and necroptosis. Importantly, we found that apoptosis and necroptosis were related according to Ramsay’s rule in the brains of the septic mice. Inhibiting the function of MD2, the crosstalk mediator of apoptosis and necroptosis, in neurons effectively reduced neuronal loss and alleviated depression-like behaviors in the septic mice. These results suggest that neuronal death in the hippocampus contributes to the mental impairments in SAE and that inhibiting neuronal MD2 is a new strategy for treatment of mental health issues in sepsis by inhibiting necroptosis and apoptosis.
Solid Waste Material Reuse Analysis: Filling the Road Subgrade with Riverway Silt and Sediment
Authors: Wang Qingzhou , Kong Liying , Tseng Ming-Lang , Song Yang , Wang Hongyu 
Published: October 2021

Abstract
This study proposes to explore solid waste material (SWM) reuse with the riverway silt and sediment, and examines the impacts of chemical composition on the road construction through sensitivity analysis. Considering the characteristics of silt mixture, it is necessary to investigate the modified materials to improve the mechanical feasibility for subgrade filling. In this study, modification schemes for construction waste and garbage slag presented well mechanical properties and environmental benefits in sensitivity analysis, especially for the high-water content silt modified by the garbage slag and lime mixture. The results indicate the lime-improved silt with medium water content is a cheap and high-performance material compared to the original silt. Moreover, modified silt demonstrated superior features in particle size, permeability and bearing capacity. Among six lime-improving schemes, the California bearer ratio (CBR2.5) increased from 7.1 to 19.6, while the minimum CBR2.5 was 2.45 times to the original silt. At last, this study proposes the engineering measures to improve the silt mixture subgrade to prevent heavy metals from polluting the water and soil environment. Further implications were also discussed.
Effect of cadmium sorption by river sediments on longitudinal dispersion
Authors: Nasrabadi Mohsen , Mazdeh Ali Mahdavi , Omid Mohammad Hossein 
Published: October 2021

AbstractThis paper concerns the cadmium sorptive effects by river bed sediments on longitudinal dispersion coefficient in an open-channel flow via experimental and numerical study. For this purpose, a circular flume was used with mean diameter of 1.6 m and a width of 0.2 m. The adsorbing bed was considered as a thin layer of the sediment particles with mean diameter of 0.53 mm and three sediment concentrations of 3, 12, and 20 gr/lit. To determine the sorption parameters of the sediments, some experiments were conducted with three cadmium concentrations of 150, 460, and 770 ppb. Then, the dispersion experiments were carried out with and without the bed sediments with the same cadmium concentration as the sorption experiments. A numerical model was then developed to solve the advection–dispersion equation with considering the sorption term by river bed sediments. The longitudinal dispersion coefficients were estimated by comparing the experimental and numerical breakthrough curves. The results showed that, with increasing the sediment concentrations, the sediment sorption rate increased and the longitudinal dispersion coefficient decreased by about 38, 36 and 33 percent, respectively, for cadmium concentrations of 150, 460 and 770 ppb. In addition, by increasing the cadmium concentrations, the changes in the longitudinal dispersion coefficient are decreased. Furthermore, a relationship was developed using non-dimensional longitudinal dispersion as a function of the new parameter of sorption ratio. From a practical point of view, the results of this study demonstrated that, at the presence of riverbed sediment, the cadmium is longitudinally dispersed with more delay in comparison with no sediment at the river bed.
Exercise and Creatine Supplementation to Augment the Adaptation of Exercise Training Among Breast Cancer Survivors Completing Chemotherapy: Protocol for an Open-label Randomized Controlled Trial (the THRIVE Study)
Authors: Patel Darpan I , Gonzalez Angela , Moon Crisann , Serra Monica , Bridges Preston Blake , Hughes Daniel , Clarke Geoffrey , Kilpela Lisa , Jiwani Rozmin , Musi Nicolas 
Published: October 2021

Background
In breast cancer survivors, chemotherapy-induced muscle loss has been shown to be attenuated with structured resistance exercise. Creatine supplementation can increase bioenergetics in skeletal muscle, which helps to improve overall strength and endurance and reduce muscular fatigue. Therefore, we hypothesize that adding creatinine supplementation to exercise training will accelerate improvements in strength, endurance, and bioenergetics in breast cancer survivors.

Objective
The primary objective is to determine the effects of combining creatine supplementation with exercise on modulating strength and physical function in breast cancer survivors by comparing these effects to those of exercise alone. The secondary objectives are to determine if creatine supplementation and exercise can increase the intramuscular storage of creatine and improve body composition by comparing this intervention to exercise alone.

Methods
We aim to test our hypothesis by conducting an open-label randomized controlled trial of 30 breast cancer survivors who have completed chemotherapy within 6 months of enrollment. Eligible participants will be equally randomized (1:1) to either a creatine and exercise group or an exercise-only group for this 12-week intervention. Individuals who are randomized to receive creatine will be initially dosed at 20 g per day for 7 days to boost the availability of creatine systemically. Thereafter, the dose will be reduced to 5 g per day for maintenance throughout the duration of the 12-week protocol. All participants will engage in 3 center-based exercise sessions, which will involve completing 3 sets of 8 to 12 repetitions on chest press, leg press, seated row, shoulder press, leg extension, and leg curl machines. The primary outcomes will include changes in strength, body composition, and physical function in breast cancer survivors. The secondary outcomes will be intramuscular concentrations of creatine and adenosine triphosphate in the vastus lateralis, midthigh cross-sectional area, and quality of life.

Results
As of October 2021, a total of 9 patients have been enrolled into the study. No unexpected adverse events have been reported.

Conclusions
Creatine is being studied as a potential agent for improving strength, endurance, and bioenergetics in breast cancer survivors following chemotherapy. The findings from our trial may have future implications for supporting breast cancer survivors in reversing the muscle loss experienced during chemotherapy and improving their physical function and quality of life.

Trial Registration
ClinicalTrials.gov NCT04207359; https://clinicaltrials.gov/ct2/show/NCT04207359

International Registered Report Identifier (IRRID)
PRR1-10.2196/26827
Incontri tra controcultura e sperimentazione fototestuale nella rivista "ABRACADABRA"
Authors: Comensoli Regaida 
Published: October 2021

Nel panorama artistico e letterario del Novecento nasce un prodotto ibrido, sviluppatosi sull’onda lunga del fenomeno Beat: le riviste underground autoprodotte. Il carattere innovativo di queste pubblicazioni non riguarda i soli contenuti, bensì anche e soprattutto la grafica, poliedrica e anticonvenzionale, ispirata alle libertà formali introdotte dalle avanguardie storiche. Fra il 1977 e il 1981 viene stampata ABRACADABRA, rivista di poesia sperimentale nata dall’incontro tra il traduttore Marcello Angioni, l’artista Harry Hoogstraten e il poeta di origine ticinese Franco Beltrametti (Locarno, 1937-1995). ABRACADABRA è un tipico esempio di pubblicazione del periodo, territorio di confine sulle cui pagine venivano sperimentati diversi gradi di interazione tra specifici linguaggi, testandone potenzialità e cortocircuiti.
Keywords: riviste autoprodotte, ABRACADABRA, controcultura, Franco Beltrametti, guerriglia semiologica.
Fotografie testi segni. Note sull’opera di Guido Guidi
Authors: Serena Tiziana 
Published: October 2021

Il testo indaga la relazione fra fotografie, rappresentazioni verbali e segniche nell’opera di Guido Guidi (1941-). Con la materia testuale e segnica, nitida e definita, offuscata e mobile, sino a divenire oggetto dell’immagine, sin dagli anni Settanta, Guidi conduce una sperimentazione linguistica sull’autonomia e l’intraducibilità del senso della fotografia.
Keywords: Guido Guidi, fotografia, materia figurativa, materia testuale, fotografia contemporanea.
Longitudinal Plasma Lipidome and Risk of Type 2 Diabetes in a Large Sample of American Indians With Normal Fasting Glucose: The Strong Heart Family Study
Authors: Miao Guanhong , Zhang Ying , Huo Zhiguang , Zeng Wenjie , Zhu Jianhui , Umans Jason G. , Wohlgemuth Gert , Pedrosa Diego , DeFelice Brian , Cole Shelley A. , Fretts Amanda M. , Lee Elisa T. , Howard Barbara V. , Fiehn Oliver , Zhao Jinying 
Published: October 2021

OBJECTIVEComprehensive assessment of alterations in lipid species preceding type 2 diabetes (T2D) is largely unknown. We aimed to identify plasma molecular lipids associated with risk of T2D in American Indians.RESEARCH DESIGN AND METHODSUsing untargeted liquid chromatography–mass spectrometry, we repeatedly measured 3,907 fasting plasma samples from 1,958 participants who attended two examinations (∼5.5 years apart) and were followed up to 16 years in the Strong Heart Family Study. Mixed-effects logistic regression was used to identify lipids associated with risk of T2D, adjusting for traditional risk factors. Repeated measurement analysis was performed to examine the association between change in lipidome and change in continuous measures of T2D, adjusting for baseline lipids. Multiple testing was controlled by false discovery rate at 0.05.RESULTSHigher baseline level of 33 lipid species, including triacylglycerols, diacylglycerols, phosphoethanolamines, and phosphocholines, was significantly associated with increased risk of T2D (odds ratio [OR] per SD increase in log2-transformed baseline lipids 1.50–2.85) at 5-year follow-up. Of these, 21 lipids were also associated with risk of T2D at 16-year follow-up. Aberrant lipid profiles were also observed in prediabetes (OR per SD increase in log2-transformed baseline lipids 1.30–2.19 for risk lipids and 0.70–0.78 for protective lipids). Longitudinal changes in 568 lipids were significantly associated with changes in continuous measures of T2D. Multivariate analysis identified distinct lipidomic signatures differentiating high- from low-risk groups.CONCLUSIONSLipid dysregulation occurs many years preceding T2D, and novel molecular lipids (both baseline level and longitudinal change over time) are significantly associated with risk of T2D beyond traditional risk factors. Our findings shed light on the mechanisms linking dyslipidemia to T2D and may yield novel therapeutic targets for early intervention tailored to American Indians.
Statistics as a discipline: A brief look to the past, the present and the future
Authors: Ojeda Ramírez Mario Miguel , Behar Gutiérrez Roberto , Grima Cintas Pere 
Published: October 2021

La estadística ha adquirido especial importancia en la era de la información y el conocimiento. Los profesionales y científicos, y también los ciudadanos, reconocen que ayuda a la recopilación, organización y análisis de datos, y que sus principios apoyan la interpretación y comunicación de los resultados obtenidos. Se acepta que es una metodología para obtener conocimiento, y así mismo una tecnología, que respalda diagnósticos, intervenciones y la toma de decisiones en contextos de incertidumbre. Este ensayo presenta una conceptualización amplia y justa de esta disciplina. También hace una caracterización de su misión y revisa brevemente su historia, tendencias y estado actual. Al final se presenta una breve visión de las perspectivas para el futuro.
Análisis comparativo de la formación de los docentes de idiomas en la educación superior ecuatoriana: la importancia de la Psicología
Authors: Narváez Carrión César Rafael , Pazmiño Calero Lucy Marina 
Published: October 2021

La formación universitaria en el Ecuador ha sufrido varios cambios en diversos ámbitos que incluyen el desarrollo curricular. El análisis de necesidades en la formación de profesionales en Pedagogía de la Enseñanza de los Idiomas Nacionales y Extranjeros ha incorporado diferentes componentes de carácter metodológico, tecnológico y social. Actualmente, dichos profesionales trabajan hacia la incorporación del aspecto psicológico. Todo ello, en vista de su importancia para la formación de los futuros profesionales, aunque no sea una tendencia absoluta. Es importante ratificarlo al tiempo que se analiza la base de las preferencias en materia metodológica y social de las diferentes prácticas de la docencia. El presente estudio se desprende del análisis efectuado para el diseño de la carrera de pedagogía de los idiomas nacionales y extranjeros en la Universidad Estatal de Bolívar. Como metodología se propone un análisis comparativo de las mallas curriculares de la universidad pública y privada para evaluar el grado de inclusión del componente psicológico y concluir con un análisis cuantitativo de la percepción de los docentes en cuanto al aporte de los profesionales en enseñanza del idioma inglés. En este aspecto se abordan específicamente los campos psicopedagógicos y de neurociencias. El estudio se respalda por una etapa de investigación bibliográfica con base en las consideraciones de las mallas curriculares. Los resultados muestran diferencias significativas del estudio de la psicología y sus afines entre la universidad pública y la privada, así como una apreciación de falta de relevancia de los aportes de los profesionales de idiomas en este campo.
Sensitivity analysis of design parameters of envelope enclosure performance in the dry-hot and dry-cold areas
Authors: Ni Pingan , Wang Wanjiang , Zheng Hanjie , Ji Wensi 
Published: October 2021

Abstract
In a bid to quantify the sensitivity of envelope enclosure’s design parameters in the dry-hot and dry-cold areas and to provide a reference for the local building performance design, this paper uses ANN modelling which combined with the improved Garson algorithm to calculate the connection weight sensitivity (CWS), the first-order sensitivity (RBD-S1 and DMIM-S1) and the global sensitivity (DMIM-delta) of the design parameters. These parameters were calculated by using different methods in SALib. Through the verification and analysis of the sensitive result, the applicability of the CWS and DMIM-delta was confirmed. Among the design parameters involved in this study, the sum of the sensitive values of S-D, S-N and S-A exceeds 60% in each performance label, and the sum of the sensitive values of WWR_S and WWR_N exceeds 20%. The performance design of envelope enclosure in this area requires applying reasonable shading components and appropriate optimisation of the North and South of WWR. After the sensitivity analysis process, the calculation efficiency of the model can be improved as far as possible without reducing the accuracy of the model in the later simplified calculation and multi-objective optimisation. The building performance simulation model has a high degree of non-linearity, and the interpretability of the model can be enhanced through the sensitivity analysis process. Although the internal calculation process is unknowable, the perception of the results caused by the input parameters is significantly enhanced.
Comparison of movement velocity and force-velocity parameters using a free video analysis software and a linear position transducer during unilateral and bilateral ballistic leg press
Authors: Martinopoulou Klimentini , Tsoukos Athanasios , Donti Olyvia , Katsikas Christos , Terzis Gerasimos , Bogdanis Gregory C. 
Published: October 2021

Abstract

Study aim: This study compared movement velocity and force-velocity profile parameters measured by a free video analysis software program, with the use of a high-speed video recording, and a validated linear position transducer (LPT).

Material and methods: Ten team-sports athletes performed double-leg and single-leg ballistic lower limb extensions on a leg press machine against a wide range of resistive loads. Each repetition was recorded by the LPT a high-speed camera (300 fps), and later analysed with a free video analysis software program.

Results: Mean and peak movement velocity presented high reliability (ICC: 0.990 and 0.988, p < 0.001) and agreement between the two measuring systems (systematic bias: –0.06 ± 0.04 and –0.01 ± 0.03 m/s, respectively). Force-velocity profile parameters were also similar: maximum velocity at zero load (Vo: 1.79 ± 0.15 vs. 1.78 ± 0.12 m/s, p = 0.64), slope (b: –1585 ± 503 vs. –1562 ± 438 N · s/m, p = 0.43), maximum force at zero velocity (Fo: 2835 ± 937 vs. 2749 ± 694 N, p = 0.41) and maximum power (1274 ± 451 vs 1214 ± 285 W, p = 0.38). Both measuring systems could similarly detect the individual force or velocity deficit (p=0.91).

Conclusion: In conclusion, a free video analysis software combined with a high-speed camera was shown to be a reliable, accurate, low bias and cost-effective method in velocity-based testing.
The impact of the covid-19 crisis on higher education
Authors: Luchian Ivan 
Published: October 2021

Abstract
The current pandemic crisis is unique in its kind, becoming a global cataclysm with a multilateral impact and an extended spread over time. Affecting all aspects of human activity, this crisis has inevitably affected the higher education system, and its consequences are manifesting both locally and internationally. The purpose of this paper was to establish the influence of crisis on the economic situation of higher education institutions. After studying of different institutions reports, analytical presentations of authors from different countries, as well as the author's communication with colleagues from different educational institutions during online academic meetings, it became possible to compile a complex picture of economic consequences of the COVID-19 crisis on higher education system. The research results showed an extremely uneven spread of the economic effects of the pandemic crisis. Thus, the least COVID-19 crisis has affected universities in industrially developed countries and the disastrous impact will manifested in developing countries. In addition, a dependence of evolution of economic situation of educational institutions of a complex of important factors was detected. It is about of change in living standard of the population, the capacity of the local authorities to manage the consequences of the pandemic, the changes in higher education policies, presiding students to do higher education, managerial ability to manage the economic and financial status of higher education institutions and others. Likewise, certain ways of solving economic problems have been outlined.