bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERBEDAAN INDIVIDU SEBAGAI FAKTOR PENYEBAB STRES KERJA PADA TENAGA KESEHATAN AKIBAT PANDEMI COVID-19: NARRATIVE LITERATURE REVIEW
Authors: Tamara Tashya Angelie , Wulandari Ratna Dwi 
Published: December 2021

Coronavirus disease yang dikenal dengan sebutan COVID-19 telah merenggut jutaan nyawa di seluruh dunia. Tenaga kesehatan sebagai seseorang yang berperan penting dalam meningkatkan derajat kesehatan masyarakat dituntut untuk bisa melakukan pelayanan terpadu yang optimal bagi masyarakat. Tekanan atau tuntutan yang dirasakan oleh tenaga kesehatan akibat pandemi COVID-19 dapat mempengaruhi kesehatan mental tenaga kesehatan, salah satunya dapat menyebabkan stres kerja. Stres dapat terjadi salah satunya dipengaruhi oleh cara individu dalam merespon tekanan yang diperoleh di tempat kerjanya. Individu yang dapat mengendalikan tekanan dari luar dengan baik dapat terhindar dari stres. Tujuan dari penelitian ini adalah untuk menganalisis perbedaan individu sebagai faktor penyebab stres kerja pada tenaga kesehatan akibat pandemi COVID-19. Jenis penelitian ini berupa narrative literature review dengan populasi jurnal sebanyak 113 artikel. Setelah, melalui proses screening, penilaian kualitas, ekstrasi data, dan kesesuaian dengan kriteria inklusi penelitian, maka diperoleh 16 artikel sebagai artikel rujukan yang dapat digunakan dalam penelitian ini. Hasil penelitian menunjukan terdapat 4 faktor perbedaan individu yang menyebabkan stres kerja pada tenaga kesehatan akibat pandemi COVID-19, yaitu persepsi negatif tentang COVID-19, pengalaman kerja yang kurang, rasa khawatir tentang COVID-19, seperti khawatir terinfeksi COVID-19 dan khawatir dapat menularkan COVID-19 pada kerabat/ keluarga terdekat, terakhir berupa dukungan sosial dari keluarga maupun rekan kerja yang rendah.Pemerintahan dan instansi terkait diharapkan dapat memperhatikan kesehatan mental tenaga kesehatan. Selain itu, tenaga kesehatan diharapkan tetap melakukan hal-hal positif yang dapat membangun semangat kerja selama masa pandemi COVID-19.
Tyrania cicha i zawoalowana według traktatu „De tyranno” Bartolusa de Saxoferrato
Authors: Szymańska Aleksandra 
Published: December 2021

The paper is devoted to the tacit and veiled tyranny, a concept developed by Bartolus de Saxoferrato in his treatise On the Tyrant (De tyranno), widely regarded as an outstanding representative of the commentator school. In addition to his strictly legal work, which consists of commentaries on individual parts of the Corpus iuris civilis, he is also the author of political and legal treatises, dealing with important topics for the inhabitants of late medieval Italy. In the treatise, he decided to discuss in detail the theme of tyranny from the perspective of a jurist interested in solving the concrete problems that tyrant rule could cause in practice. He developed ways to classify rule as tyrannical, defining and outlining its various types, so that once a tyrant is removed from power, its legal consequences can be examined, including whether legal acts committed during tyranny are valid.
The aim of this article is to analyse the tacit and disguised tyranny presented in the treatise De tyranno, to identify its essential characteristics and point out the features that distinguish it from manifest tyranny. The analysis covers the types of tyranny, the ways of hiding a tyrant, threats to rights and freedoms in the case of hidden tyranny, methods of exposing the hidden tyrant, ways of eliminating tyranny, and the validity of actions performed during tyranny. The examination of these aspects is intended not only to allow an understanding of Bartolus’ conception, but also to provide an answer to the question of the purpose singling out this form of tyranny serves.
A veiled tyrant is one who rules a community against the law, hiding this fact behind some sort of veil. As a legal category, the distinction between tyranny ex defectu tituli and ex parte exercitii is fundamental. The distinction between a manifest and hidden tyrant does not have such far-reaching consequences. Tacit and veiled tyranny are sometimes treated as transitional categories. On many points, the comments applicable to manifest tyrants also apply to veiled tyrants. The purpose of distinguishing this category is to make the problem clearer — to state that a tyrant is also someone who seemingly has nothing to do with power or has little authority. Bartolus undertook to define and characterise this form of tyranny, indicating the legal instruments that could be used to deal with the undesirable political phenomenon as long as it had not yet assumed its mature form. The jurist considered it expedient to distinguish the category of a hidden tyrant so that they could be identified and held accountable under the law, although they did not formally possess any power or had very little of it, as a usurper or as one guilty of harming citizens.
HUBUNGAN SIKAP, NORMA SUBYEKTIF DAN PERSEPSI KENDALI PERILAKU TERHADAP NIAT KTH DALAM BUDIDAYA TANAMAN ENERGI DI YOGYAKARTA
Authors: Nugroho Adi , Maulana Ahdiar Fikri , Utomo Singgih , Oktalina Silvi Nur , Nugroho Prasetyo , Wiyono Wiyono 
Published: December 2021

Energy policy in the world has changed due to the climate crisis. As a result, the need for renewable energy supply is increasing. Trees in the forestry sector are a reliable source of biomass for renewable energy production. Community forests could play an important role in supplying biomass-based renewable energy production. The study aims to understand the attitude, subjective norms, and perceived behavioural control on Farmers Forest Group's intention in cultivating trees for energy in Yogyakarta Province. The Theory of Planned Behaviour approach was used to analyse the correlation between Attitudes, Subjective Norms, and Perceived Behavioural Control on Forest Farmers Group Intention in cultivating trees for renewable energy. A survey using an online questionnaire was conducted on Forest Farmers Groups in four districts in DI Yogyakarta; Sleman, Kulonprogo, Bantul, and Gunungkidul. The survey results were analysed using non-parametric statistics.The results showed a significant positive correlation between Attitudes, Subjective Norms, and Perceived Behavioural Control on the Forest Farmers Group's Intention to cultivate trees for renewable energy. The study provides policymakers and privates with insight into working with the farmers when they are about to implement biomass-based renewable energy programs
SOFT SKILLS FORMATION IN FUTURE TEACHERS IN THE PROCESS OF TEACHING THE COURSE “COACHING TECHNOLOGIES IN EDUCATION”
Authors: Zelenska Lyudmila 
Published: December 2021

the article reveals the meaning of the concept of soft skills, their role and significance for professional development and career growth. Based on the analysis of the Professional Standard for the professions “Primary school teacher”, “General secondary school teacher”, “Primary school teacher” (with a diploma of junior specialist) (identified a list of flexible skills that must have a modern teacher. Emphasis is placed on the importance of developing soft skills in applicants for higher pedagogical education at the stage of their professional training.
Based on the study of educational programs for higher education at the bachelor’s level in specialties 013 Primary education, 014 Secondary education (by subject specialization) the ways of their formation in the educational process are determined. The curriculum of the elective discipline of the general cycle of training “Coaching technologies in education” has been developed and tested as an additional resource for the formation of future teachers’ communication skills, leadership competencies, self-management skills, intellectual skills.
Predictive Value of Immune Genomic Signatures from Breast Cancer Cohorts Containing Data for Both Response to Neoadjuvant Chemotherapy and Prognosis after Surgery
Authors: Zhu Yidan , Iwamoto Takayuki , Kajiwara Yukiko , Takahashi Yuko , Kochi Mariko , Shien Tadahiko , Taira Naruto , Toyooka Shinichi , Doihara Hiroyoshi 
Published: December 2021

Abstract
BackgroundPrevious studies of immune-related gene signatures (IGSs) in breast cancer have attempted to predict the response to chemotherapy or prognosis and were performed using different patient cohorts. The purpose of this study was to evaluate the predictive functions of various IGSs using the same patient cohort that included data for response to chemotherapy as well as the prognosis after surgery.MethodsWe applied five previously described IGS models in a public dataset of 508 breast cancer patients treated with neoadjuvant chemotherapy. The prognostic and predictive values of each model were evaluated, and their correlations were compared.ResultsWe observed a high proportion of expression concordance among the IGS models (r: 0.56-1). Higher gene expression scores of IGSs were detected in aggressive breast cancer subtypes (basal and HER2-enriched) (P < 0.001). Four of the five IGSs could predict chemotherapy responses and two could predict 5-year relapse-free survival in cases with hormone receptor-positive (HR+) tumors. However, the models showed no significant differences in their predictive abilities for hormone receptor-negative (HR-) tumors.ConclusionsIGSs are, to some extent, useful for predicting prognosis and chemotherapy response; moreover, they show substantial agreement for specific breast cancer subtypes. However, it is necessary to identify more compelling biomarkers for both prognosis and response to chemotherapy in HR- and HER2+ cases.
Response Mechanism of Sediment Organic Matter of Plateau Lakes in Cold and Arid Regions to Climate Change: a Case Study of Hulun Lake, China
Authors: Wang Wenwen , Zhao Li , Li Wei , Chen Junyi , Wang Shuhang 
Published: December 2021

Abstract
Lake organic matter is one of the important forms of terrestrial carbon, and its sedimentary evolution is affected by many factors such as climate and source. However, few studies have been conducted on the bidirectional feedback mechanism between the sedimentary evolution of organic matter and climate change in cold and arid lakes. Historical variations of the sediment organic matter (SOM) and source construction of Hulun Lake, a typical lake in the cold and arid region of China, were studied by multiple methods. The interactions and feedback mechanisms between the sedimentary evolution, climate change, and source construction change were also discussed. Overall, the characteristic indexes of the SOM showed obvious and uniform characteristics of periodical changes. The indexes were relatively stable before 1920, and fluctuated from 1920 to 1979. Since the 1980s, the total organic carbon, carbon stable isotope, and fluorescence intensity of the protein-like component in the water extractable organic matter in the SOM has increased, while the carbon to nitrogen ratio decreased. The absolute dominant contribution of terrestrial source to the SOM had changed, and the relative average contribution rate of autochthonous source increased from 17.6% before 1920 to 36.9% after 2000. The increase of temperature, strong evaporation concentration effect, and the source construction change are the important driving factors of the sedimentary evolution of organic matter in Hulun Lake.
Screening the antifungal properties of essential oils against Phytophthora colocasiae
Authors: Kalhoro Muhammad Talib , Zhang Hong , Kalhoro Ghulam Mujtaba , Faqir Yahya , Wang Fukai , Nabi Farhan , Chen Tianhong , Gao Zhixian 
Published: December 2021

Abstract
Recently Microbicidal and micro-static activities of naturally obtained botanicals have been extensively explored, generally in response to the devastating apprehension of consumers towards the safety of edible products. However, scientists are paying more interest in using bio pesticides and phytochemicals that constitute environmentally favorable, non-toxic, long-lasting, and productive substitutes for preventing many hazardous plant pathogens. This research aimed to investigate the antifungal capabilities of sage and tea tree essential oils towards taro leaf blight, the most important cause of worldwide production losses. Using synthetic fungicides is a rapid and effective approach for controlling plant diseases, but it also creates human health risks, environmental threats, and chances of pathogen resistance. The essential oils of sage and tea tree were obtained by microwave-assisted hydro-distillation, and their chemical components were analyzed using FTIR spectroscopy. The main components of the oil were Thujone and Terpinen-4-ol, in sage and tea, respectively. A casual disease agent isolated from symptomatic taro leaves is used as a test fungus and identified as Phytophthora colocasiae. The antifungal properties of both essential oils were evaluated against mycelium, sporangium, zoospores, leaf necrosis, and corm lesions. Repeated experiments showed that the minimum concentrations for obtaining 100% inhibition of mycelium, zoospore germination, sporangia formation, and leaf necrosis were estimated at 2.5 and 5.0 mg/mL of sage and tea tree oils, respectively. Outcomes of this study provide an allusion for the prevention and curation of plant diseases promptly, economically, and environmentally by using phytochemicals and plant essential oil derivatives.
Converting the existing disease surveillance from a paper-based to an electronic-based system using District Health Information System (DHIS-2) for real-time information: The Lebanese experience
Authors: Youssef Dalal , Yaghi Ayat , Jouny Abbas , Abou-Abbas Linda , Chammaa Houssam , Ghosn Nada 
Published: December 2021

Abstract
Introduction:The Ministry of Public Health in Lebanon is in the process of converting the surveillance reporting from a cumbersome paper-based system to a web-based electronic platform (DHIS-2) to have real-time information for early detection of alerts and outbreaks and for initiating a prompt response.Objectives:This paper aimed to document the Lebanese experience in implementing DHIS-2 for the disease surveillance system. It also targets to assess the improvement of reporting rates and timeliness of the reported data and to disclose the encountered challenges and opportunities. MethodologyThis is a retrospective description of processes involved in the implementation of the DHIS-2 tool in Lebanon. Initially, it was piloted for the school-based surveillance in 2014; then its use was extended in May 2017 to cover other specific surveillance systems. This included all surveillance programs collecting aggregate data from hospitals, medical centers, dispensaries, or laboratories at the first stage. As part of the national roll-out process, the online application was developed. The customized aggregated-based datasets, organization units, user accounts, specific and generic dashboards were generated. More than 80 training sessions were conducted throughout the country targeting 1290 end-users including health officers at the national and provincial levels, focal persons who were working in all public and private hospitals, laboratories, and medical centers as well. Completeness and timeliness of reported data were compared before and after the implementation of DHIS-2. The unveiled challenges and the main lessons learnt during the roll-out process were discussed.ResultsFor laboratory-based surveillance, completeness of reporting increased from 70.8% in May to 89.6% in October. Timeliness has improved from 25% to 74%. For medical centers, an improvement of 8.1% for completeness and 9.4% in timeliness was recorded before and after training sessions. For zero reporting, completeness remains the same (88%) and timeliness has improved from 74% to 87%. The main challenges faced during the implementation of DHIS-2 were mainly infrastructural and system-related in addition to poor internet connectivity and limited workforce and frequent changes to DHIS-2 versions.ConclusionImplementation of DHIS-2 improved timeliness and completeness for aggregated data reporting. Continued on-site support, monitoring, and system enhancement are needed to improve the performance of DHIS-2.
Structural Basis for Control of Bacterial RNA Polymerase Pausing by a Riboswitch and its Ligand
Authors: Walter Nils , Chauvier Adrien , Porta Jason , Deb Indrajit , Ellinger Emily , Frank Aaron , Ohi Melanie 
Published: December 2021

Abstract
Folding of nascent transcripts can be modulated by the proximal RNA polymerase (RNAP) that carries out their transcription, and vice versa. A pause of RNAP during transcription of a preQ1 riboswitch (que-ePEC) is stabilized by a previously characterized template consensus sequence and the ligand-free conformation of the nascent RNA. Ligand binding to the riboswitch induces RNAP pause release and downstream transcription termination, however, the mechanism by which riboswitch folding modulates pausing is unclear. Here, we report single-particle cryo-electron microscopy reconstructions of que-ePEC in ligand-free and ligand-bound states. In the absence of preQ1, the RNA transcript is in an unexpected hyper-translocated state, preventing downstream nucleotide incorporation. Strikingly, upon ligand binding the riboswitch rotates around its helical axis, expanding the surrounding RNAP exit channel and repositioning the transcript for elongation. Our study reveals the tight coupling by which small nascent RNA structures and their ligands can functionally regulate the macromolecular transcription machinery.
miR-424-5p Combined with miR-17-5p Has High Diagnostic Efficacy for Endometriosis
Authors: Lin Chunli , Zeng Saili , Li Miaojie 
Published: December 2021

Abstract
Purpose: Endometriosis (EMT) is a chronic benign disease with high prevalence. This study investigated the diagnostic value of serum miR-17-5p, miR-424-5p, and their combined expressions for EMT.Methods: A total of 80 EMT patients of reproductive age were included as the study subjects, and another 80 healthy women of reproductive age were selected as the control group. The whole blood samples of enrolled subjects were collected and clinical characteristics were recorded. The miR-17-5p, miR-424-5p, VEGFA, IL-4, and IL-6 levels in the serum were measured. ROC curve was used to evaluate the diagnostic efficacy of miR-17-5p and miR-424-5p expressions for EMT. Pearson correlation was performed to analyze the correlation of miR-17-5p and miR-424-5p with clinical indexes in EMT patients.Results: miR-17-5p and miR-424-5p were significantly downregulated in EMT patients. For the diagnosis of EMT, the AUC of miR-17-5p was 0.865 and cutoff value was 0.890 (91.3% sensitivity and 85% specificity), the AUC of miR-424-5p was 0.737 and cutoff value was 0.915 (98.8% sensitivity and 61.2% specificity), the AUC of miR-424-5p combined with miR-17-5p was 0.938 and cutoff value was 2.205 (93.8% sensitivity and 88.7% specificity), with the diagnostic efficacy higher than miR-424-5p or miR-17-5p alone. The expressions of miR-17-5p and miR-424-5p were negatively correlated with dysmenorrhea, infertility, pelvic pain, and rASRM stage, but not with age, BMI, menstrual disorder, and nulliparity. VEGFA, IL-4, and IL-6 were remarkably increased in EMT patients, and both were inversely associated with miR-17-5p and miR-424-5p.Conclusion: miR-424-5p combined with miR-17-5p has high diagnostic efficacy for EMT.
The Impacts of Positive Psychology and Individualism on Mental Health Status of the Elderly in China: Evidence From Chinese General Social Survey Data
Authors: Zhang Yujie 
Published: December 2021

Abstract
Background

Many previous studies have proved that positive psychology can promote mental health. However, little is known about how and when it promotes mental health in older adults.
Methods

The data of this study were sourced from the 2017 wave of Chinese General Social Survey (CGSS), involving 1,537 older adults aged 60 and above. OLS regression model was used to explore the impact of positive psychology on mental health of the elderly. Moreover, stata 16.0 was used to measure the moderating effect of individualism on the relationship between positive psychology and mental health.
Results

After controlling for demographic characteristics, socio-economic status and lifestyle factors, the regression results suggest that positive psychology was associated with mental health (coefficient = 0.112, p < 0.01). In addition, the positive relationship was significantly stronger for people who were older, married, lived in urban areas, with higher education and higher subjective social class position, and higher exercise frequency. Moreover, the moderating effect analysis results suggest that individualism strengthened the relationship between positive psychology and mental health.
Conclusions

This study reveals that positive psychology has a positive effect on mental health among the elderly, and the positive health effect shows significant age, marital status, living areas, education background, social class position and physical exercise inequalities. Furthermore, this study also provides new evidence indicating that individualism positively moderates the relationship between positive psychology and mental health. Promoting positive psychology can be a promising way for China to promote psychological care for the elderly in the future.
Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores.
Authors: De Wulf Peter , Smurova Ksenia , Stancari Stefania , Irene Carmela , Berto Giovanna , Iacovella Maria , Perticari Giulia , D'Ambrosio Ilaria , Damizia Michela , Giubettini Maria , Philippe Réginald , Baggio Chiara , Callegaro Elisabetta , Casagranda Andrea , Corsini Alessandro , Polese Vincenzo , Ricci Anna , Dassi Erik 
Published: December 2021

Abstract
Kinetochores assemble on centromeres (CENs) via histone H3 variant CENP-A and low levels of CEN transcripts. RNA polymerase II (RNAPII) activity is restrained by the CEN histone code, while CEN RNA concentrations are reduced by the nuclear exosome. Using S. cerevisiae, we add kinase Rio1 to this scheme as it downregulates RNAPII, and promotes CEN RNA turnover via exoribonuclease Rat1. Transcription factor Cbf1 and the assembled kinetochore further restrain CEN transcription. CEN transcripts exist as long (up to 11,000nt) and short RNAs (119±40nt), which may underlie CEN identity and kinetochore recruitment. While also curtailed by Rio1, Rat1, and the exosome, periCEN RNAs (<200nt) accumulate at levels that are one order of magnitude higher than the CEN transcripts. Depleting Rio1 causes CEN and periCEN RNA buildup, kinetochore malformation, and chromosome loss. Depleting human orthologue RioK1 leads to CEN RNA accumulation and micronuclei formation, suggesting that Rio1/RioK1 activity at centromeres is conserved.