bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and Preclinical Evaluation of Virus Like Particle Vaccine Against COVID-19 Infection
Authors: C Ismail Yilmaz , Ipekoglu Emre , Yildirim Muzaffer , Evcili Irem , Yilmaz Naz , Bulbul Artun , Turay Nilsu , Aydin Yagmur , Guvencli Nese , Gungor Bilgi , Saraydar Berfu , Bartan Asli Gulce , Ibibik Bilgehan , Bildik Tugce , Baydemir İlayda , Cam Sefa Burak , Dede Eda Ciftci , Gizer Merve , Erganis Osman , Sarac Fahriye , Uzar Serdar , Enul Hakan , Adiay Cumhur , Aykut Gamze , Polat Hivda , Tekin Saban , Zeytin Hasan E. , Korkusuz Petek , Gursel Ihsan , Gursel Mayda 
Published: July 2021

Background Vaccines that incorporate multiple SARS-CoV-2
antigens can further broaden the breadth of virus-specific cellular and
humoral immunity. This study describes the development and
immunogenicity of SARS-CoV-2 VLP vaccine that incorporates the 4
structural proteins of SARS-CoV-2. Methods VLPs were generated
in transiently transfected HEK293 cells, purified by multimodal
chromatography and characterized by tunable resistive pulse sensing,
AFM, SEM, and TEM. Immunoblotting studies verified the protein
identities of VLPs. Cellular and humoral immune responses of immunized
animals demonstrated the immune potency of the formulated VLP vaccine.
Results Transiently transfected HEK293 cells reproducibly
generated vesicular VLPs that were similar in size to and expressing all
four structural proteins of SARS-CoV-2. Alum adsorbed, K3-CpG ODN
adjuvanted VLPs elicited high titer anti-S, anti-RBD, anti-N IgG,
triggered multifunctional Th1 biased T cell responses, reduced virus
load and prevented lung pathology upon live virus challenge in
vaccinated animals. Conclusion These data suggest that VLPs
expressing all four structural protein antigens of SARS-CoV-2 are
immunogenic and can protect animals from developing COVID-19 infection
following vaccination.
Brucellosis Reemergence after a Decade of Quiescence in Palestine, 2015-2017: a Seroprevalence and Molecular Characterization Study
Authors: Ashhab Yaqoub , Aljanazreh Bessan , Alzatari Khaled , Tamimi Asmaa , Alsaafeen Mohammad , Hassouneh Waheed 
Published: July 2021

Brucellosis is an endemic disease in many developing countries and
ranked by the World Health Organization among the top seven “neglected
zoonoses”. Although a Palestinian brucellosis control program was
launched in 1998, the disease reemerged after 2012. Interestingly, a
similar reemerging pattern was reported in the neighboring Israeli
regions. The aim of this work was to characterize the reemerging strains
and delineate their genetic relatedness. During 2015-2017, blood samples
from 1324 suspected patients were analyzed using two serological tests.
Seropositive samples were cultured, and their DNAs were analyzed by
different genetic markers to determine the involved Brucella
species and rule out any possible involvement of the Rev.1 vaccine
strain. The rpoB gene was sequenced from 9 isolates to screen for
rifampicin resistance mutations. Multi Locus VNTR Analysis (MLVA-16) was
used for genotyping the isolates. The molecular analysis showed that all
isolates were B. melitensis strains unrelated to the Rev.1
vaccine. The rpoB gene sequences showed four single nucleotide
variations (SNVs) not associated with rifampicin resistance. MLVA-16
analysis clustered the isolates into 22 unique genotypes that belong to
the East Mediterranean lineage. Altogether, our findings show that the
reemergence of brucellosis was due to B. melitensis strains of
local origin, the Palestinian and Israeli control programs’ weaknesses
could be a major factor behind the reemergence of the disease. However,
other socioeconomic and environmental factors must be investigated.
Moreover, strengthening brucellosis control programs and enhancing
cooperation between all stakeholders is essential to ensure long-term
program outcomes to fight brucellosis.
Pengaruh Harapan Pelanggan Dan Kualitas Pelayanan Terhadap Kepuasan Pelanggan Pada PDAM Kabupaten Buleleng
Authors: Subawa Komang Arta , Telagawathi Ni Luh Wayan Sayang 
Published: July 2021

This research aimed to examine the customer effect expectations and service quality of customer satisfaction at PDAM Buleleng Regency both partial and simultan. The research design used a quantitative causal. PDAM Buleleng Regency customers as subject and the customer expectation, service quality, customer satisfaction as object,. The sample amounted 80 people. The data from questionnaire and then analyzed used multiple linear regression analysis. The results showed: (1) there are significant effect between customer expectations to customer satisfaction, (2) between service expectations to customer satisfaction had a positive and significant effect, (3) between service quality to customer satisfaction had a significant effect.
Pengaruh Kompensasi Terhadap Prestasi Kerja Pada PT Garuda Agung Kencana
Authors: Putra Gede Tresna Adi , Bagia I Wayan 
Published: July 2021

This study aims to influence the compensation on work performance at PT. Garuda Agung Kencana. The research design used in this study is causal quantitative. The subjects of this study were all employees of PT. Garuda Agung Kencana The object of this study focuses on the variables of compensation and work performance. The population of this study was 55 people. Data collection was performed by questionnaire method, which was then analyzed by simple linear regression. The results obtained in this study indicate that compensation has a positive and significant effect on work performance at PT. Garuda Agung Kencana by 64.6%
Numerical Investigation of the Stability and Spintronic Properties of Selected Quaternary Alloys
Authors: Popoola Adewumi I. , Akinpelu S. Babatunde 
Published: July 2021

The use of electronic charge and spins (spintronics) has been proposed for much better data storage. This class of material is believed to have excellent capability for data integrity, low dynamic power consumption and high-density storage that showcases excellent protection against data loss. The spintronic and related properties have been investigated on four newly proposed quaternary alloys (NbRhGeCo, NbRhGeCr, NbRhGeFe and NbRhGeNi) through the first-principles calculation method of the Density Functional Theory (DFT). Specifically, the phonon frequencies, elastic stabilities, and the electronic structure were systematically studied in the full Heusler structure. The results predict that NbRhGeFe and NbRhGeCr are elastically and structurally stable. Both NbRhGeFe and NbRhGeCo are half-metals with ferromagnetic character, but NbRhGeCo is unfortunately elastically unstable. NbRhGeCr and NbRhGeNi are non-magnetic metallic alloys in their spin channels. All the results predict NbRhGeFe to be the only suitable among all the four alloys for spintronic application.
The Relationship between the Elements of Marketing Mix and Consumer Behavior during Environmental Uncertainty:
Authors: Raewf Manaf B. , Thabit Thabit H. , Jasim Yaser A. 
Published: July 2021

Many companies are facing difficulties such as sales reduction due to the changing of consuming behavior during the period of crises. However, this research aims to understand consumer behavior, and identify influences on consumer behavior during environmental uncertainty, as well as, providing a conclusion for companies to handle the issues related to consumer needs during environmental uncertainty and crisis like COVID-19 pandemic. Therefore, managers are getting confused during the process of making marketing decisions. In addition, COVID-19 as a result of being a global pandemic, the global economy greatly affected and led to a financial crisis caused by the occurred lockdown, where the impact is not due to the disparity between supply and demand as the previous financial crisis. The researchers distributed questionnaires electronically during COVID-19 lockdown to analyze the consumer behavior in two cities of Iraq by using SPSS software, Cronbach’s Alpha, and Person Correlation were used to test the four hypotheses of research. The researchers concluded that environmental uncertainty clearly effects on the principles of consumer behavior. Moreover, during crises and pandemics such as COVID-19, the behavior of consumers is going to be changed. Additionally, the main findings were the positive relation of consumers' behavior with the price, quality, and the availability of product. While, there is a negative relation with advertisements.
Academic Hardiness in Students with Leukimia at SMA Terbuka Gambut
Authors: Zwagery Rika Vira 
Published: July 2021

This research aims to determine the academic hardiness in leukimia student. Academic hardiness is a resilient personality and strength in dealing with all academic difficulties that pressure students. The research subject was conducted on a High School Student at Sekolah Terbuka who had Leukimia. The Research method used Qualititative methods to provide an overview of academic hardiness. This study used observation and interview techniques. The results found that although the subject is a cancer patient who has limitations but he has an Academic Hardiness because it has good social support from parents and positive self-perception
The Effect of Information Services Toward Confidence Students’ in Expressing Opinions
Authors: Hutasuhut Dina Hidayati , Fadlan Muhammad Noer 
Published: July 2021

This research aims to determine the effect of information services on confidence in expressing opinions in student online lectures. The method used in this study is a quantitative method. This type of research is a quasi-experimental with the type of Pre test-post test one group design. The subjects in this study were 30 students in semesters 1 and 3 who had low confidence in expressing their opinions. The instrument used is a self-confidence scale in expressing opinions. Instruments are given before and after the implementation of information services. Data were analyzed using the Wilcoxon test. Pre-test data in the experimental group obtained an average = 73.5 while the post-test data obtained an average = 119.30. This data is in accordance with the Wilcoxon level test obtained Jcount = 132 while Jtable = 105. Based on the critical value table J for the Wilcoxon marked level test for n = 30, = 0.05 the hypothesis is accepted. That is, there is a significant effect of providing information services on confidence in expressing opinions on online student recovery.
Research of senior high school students’ economic culture formation in the conditions of development of the digital education environment
Authors: Grass Tatiana Petrovna , Petrishchev Vladimir Innokentievich 
Published: July 2021

The aim of the work is to study, analyze the state and model of the process senior high school students’ economic culture formation Materials and methods. The main research methods are theoretical analysis of scientific, psychological and pedagogical literature on the research problem, study and generalization of experience on the problem; observation, questioning, conversation, qualimetry, testing, method of expert assessments; ascertaining and formative experiment; analysis of the study; methods for mathematical statistical processing, statistical processing empirical data. The study was conducted on the basis of Krasnoyarsk State Pedagogical University named after V.P. Astafiev with bachelor’s degree and master’s degree students, high school students, teachers from educational institutions, students of universities and secondary professional educational institutions of Krasnoyarsk and Krasnoyarsk Territory. The obtained dependencies and research data made it possible to form a model of the senior high school students’ economic formation in the context of the development of the digital educational environment of the region, describing the degree of formation of each component at each level.
Justice as a function of a democratic state
Authors: Svirin Yury Alexandrovich , Gureev Vladimir Aleksandrovich , Shestov Sergej Nikolaevich , Fomenko Elena Vladimirovna , Gorbunov Mikhail Alexandrovich 
Published: July 2021

The authors analyze the history of the development of the judicial system in Russia and conclude that the court is a priori inherent in the function of legal proceedings, but the court does not always administer justice. The purpose of the study is to determine the essential features of justice, to analyze the relationship between justice and legal proceedings, to analyze the judicial process in Russia from a historical point of view, to determine the ratio of judicial and presidential power in Russia. A historical analysis of the development of the judiciary in Russia and its independence in certain historical segments was carried out; the essence of justice was determined; the independence of such legal categories as legal proceedings and justice was proved, it was proved that legal proceedings are a priori inherent in the judicial system, while justice was carried out only in democratic states where the independence of the judiciary from other authorities is ensured.
OPTIMALISASI SIMULASI, UMPAN BALIK, DAN SUPERVISI AKADEMIK UNTUK MENINGKATKAN KINERJA GURU DALAM PENERAPAN PEMBELAJARAN SAINTIFIK DI SMAN 1 PASIR SAKTI TAHUN PELAJARAN 2018/2019
Authors: Sumaryono Joko 
Published: July 2021

Seiring dengan penerapan Kurikulum 2013 maka pembelajaran saintifik menjadi bagian yang utama dalama pelaksanaan pembelajaran. Namun demikian, masih banyak keterbatasan dan kesulitan yang ditemui oleh para guru SMAN 1 Pasir Sakti. Hasil pengamatan pelaksanaan pembelajaran diperkuat dengan hasil wawancara dengan guru yang diobservasi setelah pelaksanaan pembelajaran menunjukkan para guru kesulitan dalam menerapkan pendekatan saintifik dengan kombinasi variasi metode pembelajaran kooperatif. Apalagi isu keterampilan abad 21 yang semakin menguat dan harus diintegrasikan dalam penerapan Kurikulum 2013 melalui pendekatan saintifik tersebut. Kesulitan mendapatkan sumber belajar berupa buku untuk pelajaran mengakibatkan kesulitan untuk membuat media yang mendukung pembelajaran. Kesulitan guru untuk mengintegrasikan variasi metode pembelajaran kooperatif dapat difasilitasi dengan adanya simulasi bersama. Hanya saja simulasi metode pembelajaran belum pernah dilakukan di SMAN 1 Pasir Sakti. Umpan balik yang positif berasal dari hasil simulasi akan sangat berperan dalam mendorong penerapan metode baru di kelas masing-masing.
Subjek dalam penelitian ini adalah para guru SMAN 1 Pasir Sakti yang teridentifikasi memiliki kemampuan cukup dalam menerapkan variasi metode dalam pembelajaran saintifik Tahun Pelajaran 2018/2019. Terdapat sebanyak 52 orang guru dari seluruh status guru, baik Pegawai Negeri Sipil maupun honorer. Para guru harus dapat menerapkan berbagai jenis metode dalam pembelajaran yang tertuang dalam RPP. Pelatihan secara internal, konsisten dan intens harus terus dilakukan di SMAN 1 Pasir Sakti. Pelatihan tersebut dilakukan dengan cara simulasi, presentasi, dan memberikan umpan balik.
Peningkatan kemampuan guru dalam merencanakan dan melaksanakan pendekatan saintifik dengan variasi penerapan metode kooperatif telah mencapai praktik pembelajaran yang lebih baik dalam kelas setiap guru. Simulasi, umpan balik, dan supervisi akademik menjadi alat yang tepat untuk meningkatkan kemampuan guru dan mempertahankannya praktik pembelajaran yang baik. Suasana sekolah menjadi lebih kondusif dan kompetitif karena dibangun dengan kebiasaan diskusi untuk meningkatkan kompetensi masing-masing guru dalam melaksanakan pembelajaran Saintifik di SMAN 1 Pasir Sakti. Meskipun belum semua variasi metode, hanya antara 10 s.d14 metode yang dikuasai dari 42 yang direncanakan. Pembinaan kepala sekolah sebagai pemimpin pembelajaran lebih berwibawa dan bermanfaat untuk disikapi segera dan setiap saat. Predikat kemampuan merencanakan pembelajaran saintifik pada siklus II, sudah tidak ada lagi predikat kurang dan cukup, yang ada predikat baik sebanyak 94,2%, dan sangat baik 5,8%. Predikat kemampuan melaksanakan pembelajaran saintifik pada siklus II, Pada siklus II, sudah tidak ada lagi predikat kurang dan cukup, predikat baik 90,4% dan predikat sangat baik 9,4%.
Kata Kunci: , , , Supervisi Akademik
Structural, Chemical and Optical Properties of Pure and Al-Doped Zno Thin Films Derived by Sol–Gel Dip Coating Process
Authors: Kadari Ali sadek , Ech-Chergui Abdelkader Nebatti , Mohamedi Mohamed walid , Zoukel Abdelhalim , Sabrina Tair , Mehdi Adjdir , Driss-Khodja Kouider , Amrani Bouhalouane 
Published: July 2021

Abstract
Pure and Al-doped ZnO thin films were successfully deposited with sol-gel dip coating on both substrates Si (100) and glass. The structural, chemical, morphological and optical properties as a function of the annealing temperature and dopant atomic concentration were investigated by means of X-ray diffraction, Energy dispersive X-ray, Scanning Electron Microscopy, and spectrophotometry. All the pure and doped films show a polycrystalline nature and hexagonal in structure. Accurate doping was proven by EDX. In addition, the SEM analysis revealed that the films possess uniform distribution throughout the surface and the grain dimension decreases with Al doping. From the transmittance measurements, it is see that all films are over 55% in the visible region and the band gap energy increases from 3.28 to 3.45 eV with the increase of Al concentration.
Eksplorasi Jamur-Jamur yang Berasosiasi dengan Penyakit Mati Meranting pada Tanaman Kakao di Kota Padang
Authors: Jamarun Nurbailis , Yulisyah Rummah , Nelly Novri 
Published: July 2021

Branch dieback is one of the primary diseases in cacao plants. The disease affects young shoots and twigs, causes leaves to die, and leaves them bare, interfering with photosynthesis. This study aimed to determine the causative pathogens in Padang City. The locations were: Sungai Sarik Kuranji, Lubuk Minturun Koto Tangah, and Teluk Kabung Bungus. The locations have the following criteria: age ? three years, the number of plants at the location ? 50 individuals, and found symptoms of branch dieback. The research used descriptive methods. The sample represented 10% of the total number of plants at the location, was collected randomly. The results found four species of fungi associated with the disease, namely Oncobasidium theobromae, Botrydiplodia theobromae, Fusarium decemcellulare, and Fusarium sp1.
Pathogenicity and Detection of Phytohormone (Gibberellic Acid and Indole Acetic Acid) Produced by Fusarium spp. that Causes Twisted Disease in Shallot
Authors: Lestiyani Ayu , Wibowo Arif , Subandiyah Siti 
Published: July 2021

The twisted disease is one of the essential diseases in shallots caused by Fusarium spp. This study aimed to study pathogenicity and identify Fusarium species isolated from shallot plants with twisted symptoms in Nganjuk and Bantul areas. The Fusarium isolates were identified and then tested for pathogenicity levels and the effect of the hormones GA3 and IAA on shallot symptoms. Molecular identification using NF2 and NF4 successfully identified one isolate of Fusarium oxysporum, three isolates of F. acutatum, and three isolates of F. solani. Each of these species produces different symptoms. Pathogenicity test showed that all isolates had disease incidence reaching 100%, except isolates of F. solani1 causing wilt and F. solani3 causing twisted have the lower disease incidence were 77.8% and 77.7%, respectively. The investigation caused twisted shallot related to different symptoms was tested using the Thin Layer Chromatography (TLC) method. The result indicates that all isolates did not find IAA hormone. In contrast, the hormone GA3 was found in F. solani2 and F. solani3 isolates, caused bulb rot and twisted disease, respectively. Detection of IAA, GA3, and other hormones in shallot plants showed different symptoms should be studied further.
Vamos a construir paz todos: unidad didáctica para la reflexión acerca de la construcción social y cotidiana de la paz
Authors: Fuentes-Oliveros Alison Lorena , Arévalo-Olaya Fernanda Carolina 
Published: July 2021

En este artículo presentamos el proceso de construcción de la unidad didáctica Vamos a construir paz todos, fruto del trabajo de grado para obtener el título de Trabajadoras sociales. Optamos por el paradigma cualitativo y enfoque de educación popular en clave decolonial, como ejercicio reflexivo y práctico para trascender el ámbito académico y proyectar reflexiones acerca del papel que todos tenemos en la construcción social de la paz, proceso que integramos con nuestras prácticas cotidianas y nos compete como ciudadanos. Ubicamos los conceptos de construcción social de paz, cotidianidad, diálogo de saberes y subjetividad en la educación popular, la pedagogía y la didáctica. Como fruto del proceso investigativo, creamos una unidad didáctica que a través de tres mediaciones lúdicas, aporta premisas para la reflexión acerca de la construcción social de la paz.
El rol docente del tutor y supervisor de prácticas en Trabajo Social: construcción de la reflexividad y el compromiso durante la formación a través de la supervisión
Authors: Puig-Cruells Carmina 
Published: July 2021

Este texto profundiza en temas fundamentales para la formación de los trabajadores sociales y tiene como referencia el artículo “El rol docente del tutor de prácticas y el acompañamiento al estudiante” escrito en 2004. El artículo original lo motivó la necesidad de poner en claro los roles docentes que se ejercen en las prácticas por parte del tutor y del supervisor.
La utilización del artículo referido en el desarrollo de asignaturas de prácticas y supervisión, así como su aportación para entender la complejidad de las relaciones que se establecen durante las prácticas, lo hacen, aun hoy, un texto muy consultado y citado.
Sin embargo, el inevitable y enriquecedor avance del pensamiento, sumado a las modificaciones del contexto social, han ido generando en los últimos años la necesidad de su revisión y ampliación, e incluso su reformulación.
El texto que ahora se presenta contiene elementos conceptuales originales del artículo del 2004, adaptados a la actualidad, al mismo tiempo que se presentan nuevas propuestas de profundización sobre la formación práctica. Se desarrolla y amplía la conceptualización y metodología de la supervisión en el marco de las universidades como un espacio de reflexión y revisión de las prácticas en clave de desarrollo técnico y disciplinar. Al mismo tiempo, se profundiza en los diversos roles y tareas docentes del tutor y del supervisor en el acompañamiento del estudiante. Por todo ello se encontrarán algunos párrafos que necesitan ser entendidos en la época en que fueron escritos, aunque sobre ellos, se avanza con nuevas aportaciones.
Acerca de las metodologías de intervención en Trabajo Social
Authors: Mosquera-Becerra María Janeth 
Published: July 2021

El artículo busca aportar al debate acerca de las metodologías de intervención en Trabajo Social partiendo de la hipótesis de que la crisis societal actual , demanda nuevas formas de acción profesional, teniendo en consideración los procesos de Trabajo Social en los distintos campos de desempeño profesional en la sociedad contemporánea, lo cual requiere un análisis riguroso del objeto de Trabajo Social ,las formas como ha desarrollado su contenido teórico-metodológico y de la finalidad de la intervención profesional.
Acerca de la violencia simbólica en las relaciones intergenéricas de adolescentes
Authors: Solarte-Muñoz Maiber , Ortiz-Duque Paula Andrea 
Published: July 2021

El lenguaje verbal permite acercarnos a las representaciones que los y las adolescentes configuran de acuerdo a los apelativos usados en las relaciones intergenéricas, con lo cual se puedo comprobar la existencia de jerarquías respecto a la mujer, estereotipos y el temor a la exclusión, fundamentos de la violencia simbólica.