bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determination of the Optimal Size and Location of an Electricity Generation Plant That Uses Lignocellulosic Residues From Costa Rican Northern
Authors: Valverde Juan Carlos , Arias Dagoberto , Campos Roel , Masís Charlyn , Jiménez María Fernanda , Brenes Laura 
Published: August 2021

Abstract
The northern zone of Costa Rica has extensive forestry and agro-industrial development, which generates a large number of lignocellulosic residues that do not have an economic value but could represent a vast energy potential. Therefore, the objective of this study was to determine the optimal size and location of an electricity generation plant from the forest and agro-industrial biomass. The researchers worked with two forest species residues (Gmelina arborea and Tectona grandis) and two agro-industrial residues (Anana comosus and Saccharum officinarum), representing the most extensive cultivations in the region. The material was characterized, then GIS layers of the species cultivation areas were analyzed and related to the roads and protected areas to define the twelve potential points where the power plant should be installed. Later the optimal supply radius of the plant and the optimal site conditions were determined. The study determined that the tree species have an average caloric power of 19059.50 kJ/kg, significantly higher than the agro-industrial ones (16684.9 kJ/kg). It was determined that 1,056,527.67 tons of dry biomass are generated per year, 6.5% of the biomass is arboreal, and 79.97% comes from A. comosus. Also, it was determined that the optimal supply radius for the plant is 30 km. Longer distances make the project financially unviable. Considering this, the annual energy potential of the twelve points was evaluated, which varied from 4.06 to 101.82 MW. Point eleven was determined the best positioned by the biomass source and optimal environmental conditions for establishing the power plant.
A Novel Method for Efficient Electrochemical Treatment of Actual Dyeing Wastewater With Energy Saving
Authors: Yao Jiachao , Lv Sini , Wang Zeyu , Hu Liyong , Chen Jun 
Published: August 2021

Abstract
Electro-oxidation is a promising technology for wastewater treatment with bio-refractory organic and nitrogen pollutants; however, the high energy-demanding hinders its wide application. In this study, a novel method by regulating the significant parameter during electro-oxidation process timely for actual dyeing wastewater treatment with energy saving was studied. Operating factors (i.e., flow rate, initial pH value, electrode distance, and current density) were investigated for chemical oxygen demand (COD) and ammonia removal, and results indicated that current density was the key factor which obviously influenced the electrochemical performance. Indirect oxidation by active chlorine was then confirmed as the main reaction pathway for pollutants oxidation, and the relationship between the current density and the generation of active chlorine was established, suggesting that a large part of the generated active chlorine was not utilized effectively. Subsequently, a novel method by variation of current density timely based on the reaction mechanism was proposed; results indicated that, with similar pollutant removal efficiency, energy consumption could be reduced from 31.6 kWh/m3 to 20.5 kWh/m3. Additionally, the novel system was further optimized by Box-Behnken design: COD and ammonia removal efficiencies could reach 71.8% and 100% respectively, and energy-demanding could be reduced by 45.6%.
How Do Multiple Kernel Functions in Machine Learning Algorithms Improve Precision in Flood Probability Mapping?
Authors: Baig Muhammad Aslam , XIONG Donghong , Rahman Mahfuzur , Islam Md. Monirul , Elbeltagi Ahmad , Yigez Belayneh , Rai Dil Kumar , Tayab Muhammad , Dewan Ashraf 
Published: August 2021

Abstract
With climate change, hydro-climatic hazards, i.e., floods in the Himalayas regions, are expected to worsen, thus, likely to affect humans and socio-economic growth. Precisely, the Koshi River basin (KRB) is often impacted by flooding over the year. However, studies on estimating and predicting floods still lack in this basin. This study aims at developing flood probability map using machine learning algorithms (MLAs): gaussian process regression (GPR) and support vector machine (SVM) with multiple kernel functions including Pearson VII function kernel (PUK), polynomial, normalized poly kernel, and radial basis kernel function (RBF). Historical flood locations with available topography, hydrogeology, and environmental datasets were further considered to build flood model. Two datasets were carefully chosen to measure the feasibility and robustness of MLAs: training dataset (location of floods between 2010 and 2019) and testing dataset (flood locations of 2020) with thirteen flood influencing factors. The validation of the MLAs was evaluated using a validation dataset and statistical indices such as the coefficient of determination (r2: 0.546~0.995), mean absolute error (MAE: 0.009~0.373), root mean square error (RMSE: 0.051~0.466), relative absolute error (RAE: 1.81~88.55%), and root-relative square error (RRSE: 10.19~91.00%). Results showed that the SVM-Pearson VII kernel (PUK) yielded better prediction than other algorithms. The resultant map from SVM-PUK revealed that 27.99% area with low, 39.91% area with medium, 31.00% with high, and 1.10% area with very high probabilities of flooding in the study area. The final flood probability map could add a greatt value to the effort of flood risk mitigation and planning processes in KRB.
Horizontal transfer of the n-TASE gene cluster in Burkholderia seminalis TC3.4.2R3 inferred from phylogenetic and molecular methods
Authors: Tsui Sarina , Araújo Welington Luiz 
Published: August 2021

Abstract
This study describes the n-TASE cluster in Burkholderia seminalis TC3.4.2R3, which was present in B. contaminans (CP046609.1), but absent in other related Burkholderia species. Phylogeny, comparative genomics and molecular analysis indicated it is not common to B. seminalis species, presenting similarity with homologous genes presents Aquamicrobium sp. SK-2 and B. contaminans LMG23361, probably acquired by an HGT (Horizontal Gene Transfer) event. It was not possible to determine which was the most likely donor strain of the n-TASE cluster. The HGT event did not occur in all strains of the Bcc group, nor in the B. seminalis, but it did occur punctually in the strain B. seminalis TC34.2R3. It has a correlation in biotechnological applications related processes. Aiming at understanding the involvement of the n-TASE cluster in the interaction of this bacterium in the environment, genes in this cluster will be inactivated, next.
Case Report: Both Mother and Child With Chronic HBV Infection Were Clinically Cured After PEG-IFN Treatment
Authors: Bi Xiaoyue , Zeng Zhan , Sun Fang-fang , Lin Yan-jie , Yang Liu , Li Ming-hui , Xie Yao 
Published: August 2021

Abstract
Background：Interferon is significant for chronic hepatitis B patients to get ideal treatment endpoint—functional cure, and is widely used as a first line therapy.Case presentation：We reported two cases of consanguineous patients with chronic hepatitis B. Case 1 was a 36-year-old woman with chronic hepatitis B for 13 years. Case 2 and case 1 were mother-child relationship. At the age of 2, HBsAg and HBeAg of case 2 were found to be positive during physical examination, and they received antiviral therapy together. Both mother and child were treated with Peginterferon (PEG-IFN).　Based on antiviral therapy, through prolonged interferon therapy or combined with oral medication of individualized treatment, they both achieved clinical cure.Conclusion：The outcome of the two patients suggests not only the significance of individualized antiviral therapy but also a high correlation between the response to interferon antiviral therapy and genetic background.
Investigating The Prevalence of Alcohol Consumption and Its Related Factors in 13 To 17-Year-Old Adolescents: Data Extraction From 55 Eastern Mediterranean Countries
Authors: farnia vahid , Jouybari Touraj Ahmadi , salemi safora , rahami Bahareh , moradinazar mehdi , alikhani mostafa , Majd Tahereh Mohammadi , Bahadorinia shahab 
Published: August 2021

Abstract
Background

Alcohol consumption has become very common among adolescents in recent years and its prevalence varies in different countries. The aim of this study was to investigate the prevalence of alcohol consumption and related factors in adolescents aged 13 to 17 years living in the Eastern Mediterranean Region (EMR).
Methods

The present study was a cross-sectional study that was performed on 191228 adolescents (girl, 51.1% of total) aged 13 to 17 years in 55 EMR countries. In this study, the data that were collected by the World Health Organization from students were used. In order to investigate the factors affecting alcohol consumption, univariate and multivariate logistics models with 95% confidence limits were used.
Results

The overall prevalence of alcohol consumption in adolescents was 18.2%, which was 19.2% and 17.3% in boys and girls, respectively. Multivariate analysis showed that using marijuana for more than 10 days in a month (OR = 6.27, 95%CI: 5.12–7.68), smoking (OR = 3.68, 95%CI: 3.52–3.84), having sex (OR = 3.39, 95%CI: 3.24–3.55), being alone for more than 10 days (OR = 1.84, 95%CI: 1.66–2.037), having insomnia most of the time (OR = 1.68, 95%CI: 1.54–1.83), having suicide plan (OR = 1.47, 95%CI: 1.39–1.57), being 16 and older (OR = 1.41,95%CI: 1.33–1.48), being alone sometimes (OR = 1.41,95%CI: 1.33–1.48), daily activity (OR = 1.24, 95%CI: 1.19–1.29), being beaten for 1–9 days a month (OR = 1.20, 95%CI: 1.14–1.26) increased the chances of consuming alcohol, respectively. Parental supervision most of the time and parental awareness sometimes reduced the likelihood of consuming alcohol.
Conclusions

Due to the high prevalence of alcohol consumption among adolescents living in EMR countries, it is suggested that educational, preventive and health intervention programs be conducted to raise students’ awareness of the effects of alcohol consumption in schools.
The Effects of Flaxseed Supplementation On Circulating Adipokines Concentration in Patients With Ulcerative Colitis
Authors: Morshedzadeh Nava , Rahimlou Mehran , Shahrokh Shabnam , Karimi Soheila , Chaleshi Vahid , Mirmiran Parvin , Zali Mohammad Reza 
Published: August 2021

Abstract
Introduction: Inflammatory bowel disease (IBD) is one of the most common gastrointestinal diseases that can affect people of all ages. Adipokines secreted from adipose tissue have been shown to play an important role in the pathogenesis of ulcerative colitis (UC). The aim of this study was to evaluate the effect of supplementation with your seed on the concentrations of adiponectin, resistin and visfatin in patients with UC.Methods: This trial is an open-labeled randomized controlled trial which conducted among 70 patients with UC. Patients were randomly divided into two groups: flaxseed and control. Patients in the intervention were received 30 g/day flaxseed powder for 12 weeks. Anthropometric, nutritional and biochemical factors of patients were evaluated at the beginning and end of the intervention period.Results: Totally, 64 patients (36 men and 28 women) with mean age of 31.12 ± 9.67 included in the final analysis. There wasn’t any significant difference between two groups in term of baseline weight and height (P>0.05). After the 12 weeks' intervention, flaxseed supplementation led to a significant reduction in the resistin (-4.85 ± 1.89 vs. -1.10 ± 2.25, P<0.001) and visfatin concentration (-1.33± 1.14 vs. -0.53 ± 1.63, P=0.018). Moreover, we found a significant increase in the adiponectin levels after the flaxseed supplementation (3.49 ± 1.29 vs. -0.35 ± 0.96, P<0.001).Conclusion: It has been reported in this study that flaxseed supplementation could exert beneficial effects on adipokine levels in patients with UC. Trial registration: IRCT registration no. IRCT20180311039043N1
Anti-OJ (Anti-isoleucyl-tRNA Synthetase) Autoantibody- Positive Anti-synthetase Syndrome: a Case Report
Authors: Gu Ji-Na , Yan Wang , Gao Qiao-Ling , Chen Lin 
Published: August 2021

Abstract
Background: Anti-OJ (anti-isoleucyl-tRNA synthetase) autoantibody-positive anti-synthetase syndrome(ASS) is a rare systemic autoimmune diseases that manifest as an inflammatory myopathy and interstitial lung diseas.Case presentation: We present a case of anti-OJ antibody-positive ASS with recurrent joint pain, fever, significantly elevated inflammatory markers, occult myositis but no interstitial pneumonia in a 75-year-old male patient. The patient was misdiagnosed for more than one year. Recurrent hepatocellular carcinoma (HCC) was confirmed after 1 year of the diagnosis of ASS, and the clinical symptoms were relieved after surgical resection. Conclusion: We report this rare case of anti-OJ antibody-positive ASS with atypical manifestations to raise awareness of the disease for clinicians.
The Study of Machine Learning for Wire Rupture Prediction in WEDM
Authors: Chou Ping Hsien , Hwang Yean-Ren , Yan Bling-Hwa 
Published: August 2021

Abstract
During wire electrical discharge machining (WEDM), wire rupture may deteriorate workpieces' machined surfaces and increase the processing time. However, only a few referenced papers focused on wire rupture during past decades because of its complexity. In this research, Machine Learning (ML) technique was applied to analyze the relationship between manufacturing parameters and the chance of wire rupture. Three parameters, including gap voltage (GV), feed rate (FR), and water resistance (WR), were considered as training features, and a total of 298 sets were used to train an Artificial Neural Network (ANN). The results show that the prediction accuracy of wire rupture for 10 seconds in advance is above 85%.
The Effect of Uncertainty Training on the Improvement of Diagnostic Ability in Chinese Medical Students
Authors: Xia Xiaomeng , Zeng Yi , Pi Pixiang , Wu Xianqing , Fang Xiaoling , Chen Jianlin , Zhong Yan 
Published: August 2021

Abstract
Background: To evaluate the effect of the uncertainty training on improvement of students’ diagnostic ability. Methods: Data were collected on 70 fifth year medical students enrolled in the Case Discussion courses on Obstetrics and Gynecology in the spring of 2020. Of these students, 36 were in the uncertainty training group and 34 in the control group. The effect of training was evaluated by cognitively diagnostic assessment which mapped exam questions to 4 attributes assessing clinical reasoning and basic science knowledge. Results: Uncertainty training was able to improve students’ ability to use basic science concepts for inference and problem solving, and the ability to integrate complex clinical information to arrive at a diagnosis. But it could not improve students’ ability on the basic recall of foundational concepts and the ability to use basic science concepts in clinical reasoning. Medical students could do well in integrating complex clinical information although they didn’t recall basic science knowledge well. Conclusions: Uncertainty training could be used as an effective teaching method in Case Discussion course on Obstetrics and Gynecology. However, students still need to improve their basic knowledge besides the training.
Correlation Between Structural and Ionic Transport Properties of Lithium-ion Hybrid Gel Polymer Electrolytes Based PMMA-PLA
Authors: Mazuki Norfatihah , Kufian M.Z. , Nagao Y. , Samsudin Ahmad Salihin 
Published: August 2021

Abstract
In this work, the investigation on hybrid gel polymer electrolytes (HGPEs) comprising polymethyl methacrylate (PMMA)-polylactic acid (PLA) incorporate with LiTFSI were carried out. The HGPEs samples were characterized for their structural, thermal and ionic conduction properties via FTIR, XRD, DSC, and EIS. FTIR analysis show the indication of the interaction between PMMA-PLA hybrid polymer and LiTFSI with the appearance of peak and changes in peak shifting at the coordinating site from polymer blend. The DSC analysis shows that the glass transition temperature (Tg) of HGPEs was decreased as the LiTFSI content increases, suggesting that the HGPEs system has good thermal stability. The ionic conductivity was calculated based on the Cole-Cole plot and the incorporation of LiTFSI with 20 wt. % into hybrid polymer matrixes revealed the maximum ionic conductivity of 1.02 х 10-3 S cm-1 at room temperature as the amorphous phase increases. The dissociation of ions and transport properties of the PMMA-PLA-LiTFSI systems was determined via dielectric response approach and it was found that number density (ɳ), mobility (μ), and diffusion coefficient (D) of mobile ions follows ionic conductivity trend.
Prioritization of Indicators of the Quality of Care Provided to Older Adults with Frailty by Key Stakeholders from Five Canadian Provinces
Authors: Giguere Anik , Holroyd-Leduc Jayna M. , Straus Sharon E. , Urquhart Robin , Turcotte Véronique , Durand Pierre J. , Turgeon Alexis 
Published: August 2021

Abstract
Background: To meet the needs of older adults with frailty better, it is essential to understand which aspects of care are important from their perspective. We therefore sought to assess the importance of a set of quality indicators (QI) for monitoring outcomes in this population. Methods: In this mixed-method study, key stakeholders completed a survey on the importance of 36 QIs, and then explained their ratings in a semi-structured interview. Stakeholders included older adults with frailty and their caregivers, healthcare providers (HCPs), and healthcare administrators or policy/decision makers (DMs). We conducted descriptive statistical analyses of quantitative variables, and deductive thematic qualitative analyses of interview transcripts. Results: The 42 participants (8 older adults, 18 HCPs, and 16 DMs) rated six QIs as more important: increasing the patients’ quality of life; increasing healthcare staff skills; decreasing patients’ symptoms; decreasing family caregiver burden; increasing patients’ satisfaction with care; and increasing family doctor continuity of care.Conclusions: Key stakeholders prioritized QIs that focus on outcomes targeted to patients and caregivers, whereas the current healthcare systems generally focus on processes of care. Quality improvement initiatives should therefore take better account of aspects of care that are important for older adults with frailty, such as having a chance to express their individual goals of care, receiving quality communications from HCPs, or monitoring symptoms that they might not spontaneously describe. Our results point to the need for patient-centred care that is oriented toward quality of life for older adults with frailty.
The Impact of Complications on Short-Term Outcomes of Pelvic Peritoneum Reconstruction with Barbed Suture in Laparoscopic Rectal Resection for Rectal Cancer
Authors: Wen Jing , Shen Jian , Huang Qiushi , He Shan 
Published: August 2021

Abstract
Objective: This study aimed to evaluate the safety and short-term outcomes of pelvic peritoneum reconstruction with barbed sutures in laparoscopic rectal resection for rectal cancer. Methods: This is a retrospective cohort study conducted in Chengdu second’s people hospital. The clinicopathological data of 402 patients with rectal cancer admitted to our department hospital from January to December 2019 were collected. There was total of 402 patients, including 218 males and 174 females, with an average age of 68 years. Among them, 216 patients who underwent laparoscopic rectal resection with pelvic peritoneum reconstruction (PPR) were allocated into the PPR group, and 186 patients who underwent conventional laparoscopic rectal resection were allocated into a non-PPR group. All the patients received standard preoperative and postoperative treatments. Observational indicators (1) surgical and postoperative conditions; (2) postoperative pathological examination. (3) postoperative complications. Results (1) Surgery condition: all patients in the two groups underwent successful surgery without conversion to open surgery. There were no differences between the two groups in terms of surgical approach, resection margin, tumor size, postoperative T-stage, postoperative N-stage, positive lymph nodes, harvest lymph nodes, perineal wound infection, perineal hernia, postoperative pneumonia, postoperative hemorrhage, presacral fluid, or abscess. The operative time, blood loss, the incidence of anastomotic leakage, and small-bowel obstruction showed a significant difference between the two groups. Conclusion pelvic peritoneum reconstruction with barbed suture in laparoscopic rectal resection is safe and feasible for the treatment of rectal cancer, which can significantly reduce postoperative perineal-related complications.
Contact Friction Regulation of the UV Laser Textured PVA Hydrogel and Titanium Alloy Interface
Authors: Zhou Xiaopeng , Liu Zihao , Zhu Xiaowei , Cai Yan , Chen Jie , Cao Yu 
Published: August 2021

Abstract
The soft, hydrophilic and smooth surface of hydrogel displays extremely complex friction behavior. In this work, the ultraviolet laser post-processing created PVA hydrogel surface textures is found to be a one-step effective way for the contact friction regulation at the hydrogel-titanium alloy interface. Micro-grooves with various spacings and depths are fabricated by adjusting the laser scanline interval, laser energy density and the scanning times. Friction torques are measured by a strain-controlled parallel-plate rheometer to characterize frictional behaviors of micro-grooves. At the sliding velocity range of 0.085mm/s < v < 2.3mm/s, the effect of interlocking and ploughing force are the dominant origins of friction. Frictional stress increases with the decrease of the micro-groove spacing, but not with the increase of the micro-groove depth, which indicates that frictional stress doesn’t simply increase with an increase of hydrogel’s roughness. As the velocity increases from 2.3mm/s to 100mm/s, the surface wettability of textured hydrogel plays an important role in regulating friction. Both smooth hydrogel and laser textured hydrogels show stick-slip phenomenon which occurs in the same velocity range. These results take us a step closer to deriving a more effective, accurate, and dependable guideline for designing laser-textured surface grooves for sliding friction control of hydrogel applications.