bluuebunny/crossref_metadata_2025_split huggingface dataset:
PHILOLOGISTS STUDENTS’ PROFESSIONAL COMPETENCIES FORMATION IN THE LESSON SELF-ANALYSIS PROCESS
Authors: Любов Пархета  
Published: October 2021

The article deals with the applicants' professional competencies formation in higher education in the process of self-analysis of Ukrainian literature lessons during pedagogical practices.Pedagogical practice in a higher education institution is one of the most important problems in the philology teacher's training system for practical activities in secondary schools of various types. It is a link between theoretical learning and future independent work at school. In the process of practice, theoretical knowledge acquired during training is consolidated and deepened, professional skills and abilities are developed, pedagogical thinking and creative abilities are developed, the process of formation of professional and personal qualities is intensified.Attention is paid to the peculiarities of literature lessons, the task of practical training. Ukrainian literature as a subject is the main subject of anthropology at school. Great importance was attached to these lessons by the outstanding Ukrainian pedagogue-humanist, philologist V. O. Sukhomlinsky.Among other disciplines of literature, the teacher paid special attention. In the literary work, he saw the breadth and versatility that opens space for students to think, moral and aesthetic activities. Literature as a subject, said V. Sukhomlinsky, opens the way to an independent research approach in the analysis of both the individual artistic image and the work of art as a whole. A number of practical skills that students must master in the process of different types of practices are considered. During pedagogical practice, the student-trainee must master the basics of constructive-planning, communicative-teaching, organizational, and research skills and implement them in the conditions of independent work. Algorithms for analysis and self-analysis of lessons of Ukrainian literature are presented. When evaluating a literature lesson, it is necessary to take into account such general didactic criteria as normativeness, organization, the logic of flow, scientific content, optimal methods and techniques, educational content, developmental orientation.
Conception of Culture in the Mediative Process
Authors: Trubayeva E. 
Published: October 2021

The purpose of this paper is to highlight the integrated features of the “mediation” concept in the mediation and cultural context.
The methodology. The study investigates this issue by using the basic methods and principles of cultural studies as well as a number of theoretical research methods (analysis and synthesis, comparative (compared the views of scientists, traditions, values of different cultures), and terminological analysis.
The results. The paper highlights the understanding of the notion “culture” in the mediation process that is analyzed as a means of successful communication of equal partners in a cross­cultural environment in the age of globalization. It investigates the issues of culturological empathy as a leading component of the process of interaction of individuals in a multicultural society, which determines the effective conflict­free human activity without losing their individuality. It is proved that the understanding of culturological features reveals the potential of new opportunities that ensure the coherence of actions of social actors based on the relevant cultural values.
The topicality of this paper is in the generalization of the theoretical concepts in the modern science as for interpretation of interrelations of the phenomenon of culture and mediation.
The practical significance presupposes the ways of implementation of the theoretical cultural principles in the mediation process that enhances the performance.
Dariusz Kotecki, Zrozumieć Apokalipsę? Szkice egzegetyczno-teologiczne (Biblioteka Szkoły DABAR 1; Rzeszów: Bonus Liber 2021)
Authors: Podeszwa Paweł Adam 
Published: October 2021

Recenzja książki: Dariusz Kotecki, Zrozumieć Apokalipsę? Szkice egzegetyczno-teologiczne (Biblioteka Szkoły DABAR 1; Rzeszów: Bonus Liber 2021). Ss. 294. 21 PLN. ISBN 978-83-66566-78-1
Damage identification in steel plate using FRF and inverse analysis
Authors: Khatir Samir , Abdel Wahab Magd , Tiachacht Samir , Le Thanh Cuong , Capozucca Roberto , Magagnini Erica , Benaissa Brahim 
Published: October 2021

Metaheuristic algorithms have known vast development in recent years. And their applicability in engineering projects is constantly growing; however, their deferent exploration and exploitation techniques cause the engineering problems to favor some algorithms over others. This paper studies damage identification in steel plates using Frequency Response Function (FRF) damage indicator to detect and localize the healthy and damaged structure. The study is formulated as an inverse analysis, investigating the performance of three new metaheuristic algorithms of Wild Horse Optimizer (WHO), Harris Hawks Optimization (HHO), and Arithmetic Optimization Algorithm (AOA). The objective function is based on measured and calculated FRF damage indicators. The results showed that the case of four damages with different damage severity levels presented a good challenge where the HWO algorithm was shown to have the best performance. Both in convergence speed and CPU time.
EFFECT OF PARENTERAL INFLUENZA VACCINATION ON THE CELL COMPOSITION AND ITS MICROBIOTA OF THE OROPHARYNGEAL SECRETION IN PATIENTS WITH CHRONIC INFLAMMATORY DISEASES OF THE UPPER RESPIRATORY TRACT
Authors: Timchenko M.D. , Timchenko S.V. , Volosevich L.I. 
Published: October 2021

Relevance. Until recently, the issues of changes in immunological and microbiological parameters of the oropharynx in vaccinated against viral infections remain insufficiently covered.
Objective: to determine the effect of parenteral influenza vaccination on the cellular and microbial composition of the oropharyngeal secretion in patients with chronic inflammatory diseases of the upper respiratory tract with the presence of anamnestic antibodies to vaccine strains of viruses.
Materials and methods. Oropharyngeal secretion samples of 18 patients with chronic inflammatory diseases of the upper respiratory tract studied before and 3, 12, and 36 weeks after vaccination with inactivated split influenza vaccine. As control 25 donors were used. The cell composition of the sediment was determined. A microbiological study of the oropharyngeal secretion was performed.
Results. At 3 and 12 weeks after vaccination, vaccinated patients significantly changed the relative rates of entry into the oropharyngeal secretion of lymphocytes and the composition of its microbiota while maintaining its total number. After 36 weeks, the cell composition and the representation of pathogenic and opportunistic microflora practically returned to baseline with a significant increase in the total microbiota.
Conclusions. Parenteral administration of inactivated split vaccine to persons with chronic inflammatory diseases of the upper respiratory tract with the presence in the blood of anamnestic antibodies to vaccine strains of viruses is accompanied by a simultaneous temporary increase in lymphocyte representation with a simultaneous decrease in the number of transfusion microflora in the oropharyngeal secretion.
CORRELATION OF GLYCOSYLATED HEMOGLOBIN LEVELS WITH AUDITORY AND VISUAL REACTION TIME IN DIABETICS
Authors: Patil Shweta , Phatale Sangita , Malipatil Basavaraj 
Published: October 2021

Relevance. Diabetes mellitus is a group of metabolic disorders wherein hyperglycemia occurs either due to lack of insulin secretion and/or reduced insulin sensitivity of the tissues. One of the commonest complications of diabetes is neuropathy and its severity will depend on how long and how high the hyperglycemia has been prevalent. Chronic hyperglycemia in diabetes affects the peripheral nerves and slows psychomotor responses in persons who do not have proper glycemic control. This decreased psychomotor response because improper glycemic control affects the reaction time in diabetics.
Objective: to assess and compare the auditory and visual reaction time in group-1 and group-2 diabetics and to correlate it with glycosylated hemoglobin (HbA1c) levels in both the groups.
Methods. The study was conducted on 60 subjects aged between 40-50 years after obtaining the permission of the ethical committee of our institution. The group consisted of 60 well-controlled diabetic patients (HbA1c < 7%) with a history of diabetes for 1-10 years attending the medical OPD of Basaveshwar teaching and general hospital, Gulbarga. Diabetics with HbA1c 5-6% were grouped as group-1 and those with HbA1c 6-7% as group 2. The visual reaction time for a green and red light and auditory reaction time for tone and click sound were measured by using reaction time apparatus 2x4, Anand agencies Pune. HbA1c was done by the micro-column method.
Results. The visual and auditory reaction time of diabetics with HbA1c 5-6% was faster as compared to the diabetics with HbA1c 6-7% with P< 0.001 and a statistically significant positive correlation was found between HbA1c levels and the visual and auditory reaction time.
Conclusion. Poor glycemic control slows psychomotor responses and thus affects the visual and auditory reaction time.
Magnetically sensitive nanocomplex enhances antitumor efficacy of dendritic cell-based immunotherapy
Authors: Khranovska N. , Skachkova O. , Gorbach O. , Inomistova M. , Orel V. 
Published: October 2021

Summary. Background: One of the major factors restricting in vivo efficacy of dendritic cells (DCs) based immunotherapy is the inefficient migration of these cells to the lymphoid tissue, wherein DCs activate antigen-specific T cells. A fundamentally new approach for the possibility of enhancing the antitumor effects of DC-based immunotherapy may be the use of magnetically sensitive nanocomplexes to increase the target delivery of DCs to the lymph nodes of the recipient. Aim: To study the antitumor and immunomodulatory effects of the DC-nanovaccine with magnetosensitive properties and its influence on the immunosuppressive tumor microenvironment in mice with sarcoma 37. Materials and Methods: The antitumor, antimetastatic and immunomodulatory effects of DCs loaded with magnetic nanocomplex under magnetic field (MF) control in mice with sarcoma 37 have been investigated. Results: Combined therapy contributed to a significant reduction in tumor volume and weight compared to the control group of mice and mice that received the DC vaccine without MF. Therapy with magnetically sensitive DC nanovaccine with and without the addition of the MF was accompanied by a significant down-regulation of the level of FoxP3, transforming growth factor β, interleukin (IL)-10 and vascular endothelial growth factors, mRNA expression in tumor tissues. A significant increase in interferon-γ and IL-4 mRNA expression was found in mice treated with the magnetically sensitive DC nanovaccine under MF control. Conclusion: A significant increase in the antitumor efficacy of the DC vaccine can be achieved using magnetosensitive nanocarriers of tumor antigens under MF control.
Neutrophil to lymphocyte ratio as a prognostic marker for non-metastatic renal cell carcinoma — does it add to what we already know?
Authors: Rawoot S. , Punatar C. , Singh V. , Anand A. , Shah B. , Nagaonkar S. , Joshi V. 
Published: October 2021

Summary. Aim: To study the correlation of pre-operative neutrophil to lymphocyte ratio (NLR) with pathological stage, Fuhrman grade, sarcomatoid differentiation, tumor necrosis and lymph node positivity and its prognostic role in non-metastatic renal cell carcinoma (non-mRCC). Materials and Methods: This retro-prospective, observational study was done at a tertiary care center in Mumbai, India. All patients with non-mRCC from July 2015 to April 2018 were included. Patients with co-existing systemic infection, prior immunotherapy, and long-term steroids were excluded. NLR closest to surgery, but within one month prior to surgery was used. Patients were stratified as NLR ≥ 3.0 or < 3. NLR was correlated with known prognostic factors by Pearson’s correlation. Results: 113 patients, aged 18–81 years (83 males and 30 females) were included. 75% had clear cell RCC. 62% had stage 1 disease. 58% patients had Fuhrman Grade 2. 10 patients had lymph node metastasis, 6 had sarcomatoid differentiation, 40 had tumor necrosis. The NLR was < 3 in 72 patients. Statistically significant correlation between NLR and tumor stage (p = 0.0054) as well as NLR and tumor necrosis (p = 0.0128) was shown. Conclusions: NLR correlates significantly with higher T stage and tumor necrosis. NLR may be integrated with well-established prognostic markers to improve the accuracy of prognostic scores.
Can SARS-CoV-2 change individual radiation sensitivity of the patients recovered from COVID-19? (experimental and theoretical background)
Authors: Chekhun V.F. , Domina E.A. 
Published: October 2021

Summary. R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of the National Academy of Science of Ukraine has been studying the mechanisms and specificities of individual radiation sensitivity (IRS) formation in professionals who work in the field of ionizing radiation, cancer patients and representatives of other population groups. Our data based on the use of G2-test in in vitro irradiated blood lymphocytes in late G2-period of cell cycle indicated an increased carcinogenic risk in professionals with high IRS. We suggest that the COVID-19 pandemic could make significant adjustments in the formation of IRS in professionals who have survived the disease and continue to work with ionizing radiation (IR). Increased systemic inflammatory activity, which persists for a long time in COVID-19 patients, in combination with low-dose range irradiation (professionals who continue to work with IR) and with local irradiation in the high-dose range (radiation therapy for cancer patients) may affect IRS. Repeated determination of IRS in professionals who have had COVID-19 infection, using chromosomal G2-radiation sensitivity assay will answer the question: can SARS-CoV-2 coronavirus affect the IRS? The proposed hypothesis of the radiosensitivity evolution needs further experimental validation using a set of radiobiological indices to clarify the mechanism of IRS formation following COVID-19 infection. The detected changes (increase) of human IRS after COVID-19 must be taken into account for personalized planning of radiotherapy of COVID-19 cancer patients.
Considerações Sobre a Terapia de Captura de Nêutrons pelo Boro
Authors: Campos Tarcisio Passos Ribeiro de 
Published: October 2021

Este artigo descreve a técnica de radioterapia chamada “Boron Neutron Capture Therapy” (BNCT), isto é, Terapia de Captura de Nêutrons por Boro. Serão abordados conceitos básicos em BNCT, em particular como esta técnica tem sido usada na tentativa de combater glioblastoma multiforme. Uma breve revisão histórica dos estudos clínicos feitos nas décadas de 50 e 60 será apresentada, incluindo resultados recentes do Laboratório Nacional de Brookhaven - BNL e do Instituto Tecnológico de Massachusetts - MIT. A experiência japonesa na área será comentada. Atualmente, novas ensaios clínicos no MIT e BNL foram iniciados, tentando obter a cura para o glioblastoma multiforme e melanoma intracranial periférico. Dados radiobiológicos e protocolos clínicos usados na Fase I do MIT serão apresentados. Considerações de como BNCT poderá ser aplicado no Brasil serão traçadas. O artigo aponta para a possibilidade de utilização da braquiterapia via Cf-252 acoplada à técnica de terapia de captura de nêutrons – NCT como uma alternativa simples e barata de implementação de BNCT no país.
Kegiatan Pengabdian Sirkumsisi dan Penyuluhan Kesehatan
Authors: Arfah Arni Isnaini , AM Nasrudin , Royani Ida , Rijal Syamsu 
Published: October 2021

Kegiatan yang berorientasi kepada masyarakat merupakan merupakan salah satu tridarma perguruan dibidang pengabdian. Dukungan dari berbagai pihak yang mengajak kerjasama dengan Fakultas Kedokteran UMI untuk mengadakan kegiatan bakti sosial dalam rangka Milad UMI ke 67 tahun dan Milad Fakultas Kedokteran ke 29 tahun. Oleh karena itu, kami dari Fakultas Kedokteran UMI bekerjasama dengan LPkM UMI, RS Ibnu Sina, dan Forum Komunikasi (Forkom) Kelapa Tiga menyalurkan bantuan tenaga dan materi di lokasi wilayah Kelapa Tiga Makassar berupa Sirkumsisi Massal dan Penyuluhan Kesehatan.
Kegiatan ini diagendakan pada tanggal 19 Juni 2021yang bertempatkan di Mesjid Al-Hilal, Jl.Kelapa Tiga. Kel.Ballaparang, Makassar, Sulawesi Selatan. Pelaksanaan kegiatan Sirkumsisi dengan jumlah total peserta sirkumsisi ada 44 orang dari 45 peserta yang mendaftar, untuk pergantian verban setelah sirkumsisi, kami arahkan anak-anak ke pihak Puskesmas setempat dengan kebutuhan bahan kami sediakan dari FK UMI. Penyuluhan Kesehatan dengan judul Demam Berdarah dan PHBS dengan peserta penyuluhan ada 55 orang. Untuk kegiatan penyuluhan dihadiri oleh orang tua anak-anak yang disirkum serta warga sekitar lokasi kegiatan. Tema penyuluhan membahas tentang penyakit demam berdaarah dan pentingnya perilaku hidup bersih dan sehat, sesuai keadaan saat ini kondisi cuaca yang kurang baik sehingga penyakit DBD dapat terjadi serta kondisi pandemik sekarang sehingga PHBS sangat penting untuk menjaga diri, keluarga, dan lingkungan sekitar.
Effect of Diabetes Self-Management Education (DSME) with and without Motivational Interviewing (MI) on Glycemic Control among Children and Adolescents with Type 1 Diabetes Mellitus: A Randomized Controlled Trial
Authors: Lertbannaphong Ornsuda , Hantanasiriskul Pimonsri , Kiattisakthavee Pornpimol , Ruangson Sunsanee , Sitdhiraksa Nantawat , Santiprabhob Jeerunda 
Published: October 2021

Background: Type 1 diabetes mellitus (T1DM) is a chronic disease that is difficult to control. Motivational interviewing (MI) is a collaborative style of communication that was designed to strengthen a person’s motivation and commitment to change and improve. We hypothesized that applying MI to diabetes care would lead to improved glycemic control and improved diabetes self-care behavior.
Methods: Subjects were T1DM patients aged 10-18 years with HbA1C ≥8% that were recruited from the Outpatient Diabetes Clinic during October 2016 - March 2017. Subjects were randomized into the diabetes self-management education (DSME) or DSME plus MI groups. HbA1C levels, diabetes knowledge test, and diabetes self-care behavioral questionnaire were performed.
Results: Thirty-five patients (17 DSME, 18 DSME + MI) completed the study. Baseline HbA1C was not significantly different between groups. At the end of the study, HbA1C levels were not significantly different within or between groups. From pre-intervention to post-intervention, diabetes knowledge scores were significantly increased, and self-care behavioral scores were significantly increased for dietary control and medical taking. Transition to the stages of change action stage was increased from 0 to 12 persons.
Conclusions: The effectiveness of MI on glycemic control was not found to be statistically significant at 6 months. However, continuation of DSME in T1DM patients is necessary for improving diabetes knowledge and care. Further study in a larger sample size with longer duration of MI and follow-up is needed to conclusively establish the value of MI on glycemic control in pediatric T1DM.
Renal Outcomes of Childhood IgA Nephropathy and Henoch Schönlein Purpura Nephritis
Authors: Chaiyapak Thanaporn , Pattaragarn Anirut , Supavekin Suroj , Piyaphanee Nuntawan , Lomjansook Kraisoon , Pooliam Julaporn , Sumboonnanonda Achra 
Published: October 2021

Background: Henoch-Schönlein purpura nephritis (HSPN) is considered the systemic form of IgA nephropathy (IgAN). However, differing clinicopathological features and renal outcomes of children with IgAN and HSPN have been reported in some studies.
Methods: This study retrospectively reviewed children with IgAN and HSPN younger than 18 years, between January 2004 and December 2015. The clinicopathological characteristics at diagnosis and the renal outcomes after at least 1 year of follow-up were compared between the two groups.
Results: A total of 54 children, comprising 21 with IgAN and 33 with HSPN, were recruited. The children with HSPN were younger than the children with IgAN. Gross hematuria and nephritic syndrome at the initial presentation were more common in children with IgAN. Regarding the pathological findings, IgAN had greater chronicity than HSPN. After a median follow-up period from first presentation to renal outcomes measurement of 4.0 years (1.3-12.2) in children with IgAN and 4.2 years (1.1-11.4) in children with HSPN, the renal outcomes were better in the latter group. The incidence of chronic kidney disease (CKD) was 28.6% in children with IgAN and 6.1% in children with HSPN (p = 0.02). Complete recovery was observed more frequently in children with HSPN than in children with IgAN (57.1% in IgAN vs. 87.9% in HSPN, p = 0.01).
Conclusions: Childhood IgAN has greater chronicity and worse renal outcomes than childhood HSPN, with a lower rate of complete recovery and a higher frequency of CKD. We recommend long-term follow-up for CKD in children with IgAN.
Conocimientos locales y desarrollo sostenible en Perú. El proyecto SIPAM Agrosistemas de alta montaña
Authors: Pérez Galán Beatriz 
Published: October 2021

En esta contribución se reflexiona sobre las bases sociales y culturales de los sistemas agrícolas tradicionales en el caso de los pueblos indígenas al sur de los andes peruanos. El ejemplo se extrae del proyecto piloto “agroecosistemas de alta montaña, de Machupicchu al lago Titicaca” integrado al programa SIPAM (FAO-GEF).
Desde una perspectiva antropológica crítica y con el énfasis puesto en la matriz cultural de las prácticas agrícolas tradicionales indígenas en este texto se analiza la concepción estática, reificada, homogénea, y esencialista que es atribuida en la práctica por el discurso conservacionista y del desarrollo sostenible a los conocimientos locales indígenas en este proyecto, lo que dificultaría en la práctica su conservación.
Raspberry plant mycobiom under the influence of complex organic-mineral fertilizer viteri in the Central Forest Steppe of Ukraine
Authors: Mineralova V. , Parfenuk A. , Beznosko I. 
Published: October 2021

The results of research on the influence of foliar treatment of raspberry plants with organic fertilizer VITERI on the population size and species composition of micromycetes in the mycobiome of the rhizosphere and vegetative organs of raspberry plants of Joan J in the Central Forest-Steppe of Ukraine are presented. Microbiological, phytopathological, mycological methods and methods of sampling of raspberry plants during the growing season were used for the study. To determine the effect of VITERI fertilizer on the mycobiota of the rhizosphere and vegetative organs of raspberry plants during plant ontogeny, additional foliar treatment was performed with 1% aqueous solution of VITERI fertilizer. It was found that the population is dominated by fungi of following species: Septoria rubi, West, Aspergillus niger, V. Tiegh, Alternaria alternata, (Fr.) Keissl, Fusarium spp. These micromycetes are producers of mycotoxins and can cause disease in animals and humans, as well as contribute to biological contamination of agroecosystems. During foliar treatment of raspberry plants with VITERI fertilizer, a significant decrease in phytopathogenic load was observed in the phase of intensive fruiting compared to other phases of ontogenesis of raspberry plants.