bluuebunny/crossref_metadata_2025_split huggingface dataset:
Success criteria-based impacts of risk factors on education building projects in southwestern Nigeria
Authors: Adedokun Olufisayo Adewumi , Egbelakin Temitope , Adedokun Deborah Oluwafunke , Adafin Johnson 
Published: November 2021

Purpose
Despite the huge capital outlay in tertiary education building projects (TEBP), these projects undoubtedly failed in meeting the set objectives of cost, time and quality, among others. Therefore, rather than the impacts of risks on the overall project performance, which is common in the construction management literature, the purpose of this study is to assess the impacts of risk factors on the criteria for measuring the success of public TEBP.

Design/methodology/approach
The paper adopted a quantitative research method where the data collection was via a questionnaire survey. The researcher administered 452 questionnaires to the client representatives, consultants and contractors involved in building projects across five public tertiary education institutions in Ondo State, Nigeria. Of 452 questionnaires, 279 were retrieved and suitable for the analysis, translating to a 61.73% response rate. The reliability analysis of the research instrument showed 0.965 and 0.807, via Cronbach’s alpha test, indicating high reliability of the instrument used for data collection.

Findings
The study found different risk factors affecting the criteria for measuring the success of TEBP. For instance, the environmental risk factor significantly impacted completion to cost, while financial and political risk factors significantly impacted completion to time. In addition, while environmental, legal and management risks significantly impacted end-user satisfaction, safety performance was significantly impacted by logistic, legal, design, construction, political and management risks. Besides, the logistic, legal, design, construction, financial, political and management risk factors impacted profit. However, despite profit being one of the criteria for measuring the success of building projects, it recorded the highest risk impacts amounting to 41% variance.

Research limitations/implications
The findings are limited to the public tertiary education building projects procured via competitive tendering; therefore, the results might differ when considering other procurement methods.

Practical implications
The practical implication is that rather than focusing on all risk factors, the project stakeholders could give adequate attention to the significant risk factors impacting each of the parameters for measuring the success of education building projects.

Originality/value
The study revealed specific risk factors impacting the criteria for measuring the success of TEBP, which extend beyond the use of the overall project performance approach.
Consumer interpretations of fashion sustainability terminology communicated through labelling
Authors: Ritch Elaine L. 
Published: November 2021

PurposeThe purpose of this research is to examine how consumers interpret and understand sustainable fashion production and how this informs their fashion consumption practice.Design/methodology/approachThe research adopts an interpretivist approach with in-depth interviews with 28 participants. Sampling criterion sought consumers already engaged with sustainable production – professionally working mothers – to explore how their sustainability knowledge was evaluated for sustainable fashion claims. Garment labels that descripted facets of sustainable production were introduced to encourage discourse of sustainable fashion knowledge.FindingsThe findings illustrate that sustainable fashion production is not understood and efforts to apply sustainability concepts were often misunderstood which led to scepticism for higher pricing and marketing claims. Despite this, there was concern for the wider implications of sustainability.Research limitations/implicationsLimitations include the small sample from one geographical area (Edinburgh), despite the richness of the data collected.Practical implicationsThe research offers practical advice for fashion marketers to educate consumers through effective communication strategies how sustainable fashion concepts improve consumer concerns surrounding fashion production.Social implicationsThe research indicates increased concern for fashion sustainability, something that fashion retailers should be mindful of.Originality/valueThere has been little research examining consumer interpretation of sustainable fashion terminology, and this research adds to understanding how sustainability is evaluated within fashion production.
Moderated mediation and J-curve emergence in path models: an information systems research perspective
Authors: Kock Ned 
Published: November 2021

PurposeJ-curve relationship analyses can provide valuable insights to information systems (IS) researchers. This paper aims to discuss moderated mediation in IS research and the related emergence of J-curve relationships.Design/methodology/approachBuilding on an illustrative study in the field of IS, the author Lays out three steps to combine moderation and J-curve analyses, with the goal of more fully understanding the underlying moderated mediation relationships. The paper proposes a new segmentation delta method to test for J-curve emergence, as part of this framework.FindingsThe paper shows, in the context of this study, the complementarity of moderation and J-curve analyses.Research limitations/implicationsCurrently, IS researchers rarely conduct moderation and J-curve analyses in a complementary way, even though there are software tools, and related methods, which allow them to do so in a relatively straightforward way.Originality/valueThe analyses were conducted with the software WarpPLS, a widely used tool that allows for moderated mediation and J-curve analyses, in a way that is fully compatible with the set of steps presented in this paper.
Program evaluation practices and the training of PhD students in STEM
Authors: Reeves Philip M. , Claydon Jennifer , Davenport Glen A. 
Published: November 2021

Purpose
Program evaluation stands as an evidence-based process that would allow institutions to document and improve the quality of graduate programs and determine how to respond to growing calls for aligning training models to economic realities. This paper aims to present the current state of evaluation in research-based doctoral programs in STEM fields.

Design/methodology/approach
To highlight the recent evaluative processes, the authors restricted the initial literature search to papers published in English between 2008 and 2019. As the authors were motivated by the shift at NIH, this review focuses on STEM programs, though papers on broader evaluation efforts were included as long as STEM-specific results could be identified. In total, 137 papers were included in the final review.

Findings
Only nine papers presented an evaluation of a full program. Instead, papers focused on evaluating individual components of a graduate program, testing small interventions or examining existing national data sets. The review did not find any documents that focused on the continual monitoring of training quality.

Originality/value
This review can serve as a resource, encourage transparency and provide motivation for faculty and administrators to gather and use assessment data to improve training models. By understanding how existing evaluations are conducted and implemented, administrators can apply evidence-based methodologies to ensure the highest quality training to best prepare students.
Recent advances in structural studies of the Legionella pneumophila Dot/Icm type IV secretion system
Authors: Kitao Tomoe , Kubori Tomoko , Nagai Hiroki 
Published: November 2021

AbstractThe intracellular bacterial pathogen Legionella pneumophila utilizes the Dot/Icm type IV secretion system to translocate approximately 300 effector proteins to establish a replicative niche known as the Legionella‐containing vacuole. The Dot/Icm system is classified as a type IVB secretion system, which is evolutionarily closely related to the I‐type conjugation systems and is distinct from type IVA secretion systems, such as the Agrobacterium VirB/D4 system. Although both type IVA and IVB systems directly transport nucleic acids or proteins into the cytosol of recipient cells, the components and architecture of type IVB systems are much more complex than those of type IVA systems. Taking full advantage of rapidly developing cryo‐electron microscopy techniques, the structural details of the transport apparatus and coupling complexes in the Dot/Icm system have been clarified in the past few years. In this review, we summarize recent progress in the structural studies of the L. pneumophila type IVB secretion system and the insights gained into the mechanisms of substrate recognition and transport.
The association between elevated serum interleukin‐22 and the clinical diagnosis of axial spondyloarthritis: A retrospective study
Authors: Sagiv Michal , Adawi Mohammad , Awisat Abid , Shouval Aniela , Peri Regina , Sabbah Firas , Rosner Itzhak , Kessel Aharon , Slobodin Gleb 
Published: November 2021

AbstractObjectiveThere is an unmet need for a reliable biomarker for the differentiation of axial spondyloarthritis (AxSpA) from its mimickers. Serum levels of interleukin‐22 (IL‐22) have previously been found to be significantly elevated in patients with AxSpA compared with healthy individuals or persons with osteoarthritis.MethodsConsecutive patients with established or suspected AxSpA were enrolled. The clinical data, as well as results of laboratory and imaging studies, were acquired from patients’ charts. The final diagnosis of definite or probable SpA, or an alternative diagnosis, was determined, and the serum levels of IL‐22 were examined by enzyme‐linked immunosorbent immunoassay.ResultsInterleukin‐22 levels were significantly higher in patients with definite AxSpA (29 patients) compared with patients with alternative diagnoses (14 patients) and healthy volunteers (16 individuals; P < 0.001 for both comparisons). The sensitivity and specificity of the serum IL‐22 for the AxSpA diagnosis were 0.68 (95% CI 0.49‐0.84) and 0.86 (95% CI 0.68‐0.95), respectively, for the cut‐off value of 5 pg/mL. In patients with AxSpA, serum IL‐22 levels did not correlate with modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Ankylosing Spondylitis Disease Activity Score (ASDAS), or serum C‐reactive protein.ConclusionSerum IL‐22 levels are elevated in patients with the clinical diagnosis of AxSpA and can potentially serve as an independent biomarker for the differentiation of AxSpA from its non‐inflammatory mimickers.
Aspirin for the prevention of pre‐eclampsia in women with pre‐existing diabetes: Systematic review
Authors: Zen Monica , Haider Rabbia , Simmons David , Peek Michael , Nolan Christopher J. , Padmanabhan Suja , Jesudason Shilpa , Alahakoon Thushari I. , Cheung Ngai Wah , Lee Vincent W. 
Published: November 2021

BackgroundThere is a lack of evidence for pre‐eclampsia prophylaxis with aspirin in women with pre‐existing diabetes mellitus (DM).AimsTo examine the evidence for aspirin in pre‐eclampsia prophylaxis in women with pre‐existing DM.Material and MethodsAn electronic search using Ovid MEDLINE, Embase, CinicalTrials.gov and the Cochrane CENTRAL register of controlled trials through to February 2021 was performed. Reference lists of identified studies, previous review articles, clinical practice guidelines and government reports were manually searched. Randomised controlled trials (RCTs) of aspirin vs placebo for pre‐eclampsia prophylaxis were included. Articles were manually reviewed to determine if cohorts included women with DM. The systematic review was performed following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses statement. Data from included trials were extracted independently by two authors who also independently assessed risk of bias as per the Cochrane Handbook criteria version 5.1.0. Data were analysed using Rev‐Man 5.4.ResultsForty RCTs were identified, of which 11 included a confirmed subset of women with DM; however, data were insufficient for meta‐analysis. Meta‐analysis of 930 women with DM, from individual patient data included in a systematic review and unpublished data from one of the 11 RCTs, showed a non‐significant difference in the outcome of pre‐eclampsia in participants treated with aspirin compared to placebo (odds ratio 0.58; 95% CI 0.20–1.71; P = 0.33).ConclusionsPre‐eclampsia risk reduction with aspirin prophylaxis in women with pre‐existing DM may be similar to women without pre‐existing DM. However, randomised data within this meta‐analysis were insufficient, warranting the need for further studies within this high‐risk group of women.
Atypical de Winter ECG pattern may be the mirror image of ST elevation
Authors: Wang Jian , Li Jingsen , Diao Shuling , Xu Huipu , Ding Faming 
Published: November 2021

AbstractBackground: The de Winter ECG pattern of ST‐segment depression and tall symmetrical T waves, known as an ST elevation equivalent, accounts for approximately 2% of patients with occlusion of the proximal left anterior descending (LAD) coronary artery. The classic de Winter pattern is restricted to cases without ST elevation. However, mixed cases with different types of ST deviation have been described. Here, we describe an interesting case as an example of an ST elevation myocardial infarction (STEMI) equivalent, showing transient transmural ischemia of the inferolateral myocardium, with ECG changes that mimic the de Winter pattern.
Population‐based study of multisystem inflammatory syndrome associated with COVID‐19 found that 36% of children had persistent symptoms
Authors: Kahn Robin , Berg Stefan , Berntson Lillemor , Berthold Elisabet , Brodin Petter , Bäckström Fredrik , Compagno Michele , Fasth Anders , Lingman Framme Jenny , Horne AnnaCarin , Hätting Josefin , Król Petra , Kukka Antti J , Mossberg Maria , Månsson Bengt , Nordenhäll Charlotta , Idring Nordström Selma , Khammari Nyström Fatine , Palmblad Karin , Rasti Reza , Rudolph André , Rydenman Karin , Sundberg Erik , Säve‐Söderbergh Eva , Altman Maria 
Published: November 2021

AbstractAimOur aim was to describe the outcomes of multisystem inflammatory syndrome in children (MIS‐C) associated with COVID‐19.MethodsThis national, population‐based, longitudinal, multicentre study used Swedish data that were prospectively collected between 1 December 2020 and 31 May 2021. All patients met the World Health Organization criteria for MIS‐C. The outcomes 2 and 8 weeks after diagnosis are presented, and follow‐up protocols are suggested.ResultsWe identified 152 cases, and 133 (87%) participated. When followed up 2 weeks after MIS‐C was diagnosed, 43% of the 119 patients had abnormal results, including complete blood cell counts, platelet counts, albumin levels, electrocardiograms and echocardiograms. After 8 weeks, 36% of 89 had an abnormal patient history, but clinical findings were uncommon. Echocardiogram results were abnormal in 5% of 67, and the most common complaint was fatigue. Older children and those who received intensive care were more likely to report symptoms and have abnormal cardiac results.ConclusionMore than a third (36%) of the patients had persistent symptoms 8 weeks after MIS‐C, and 5% had abnormal echocardiograms. Older age and higher levels of initial care appeared to be risk factors. Structured follow‐up visits are important after MIS‐C.
GELAD chemotherapy with sandwiched radiotherapy for patients with newly diagnosed stage IE/IIE natural killer/T‐cell lymphoma: a prospective multicentre study
Authors: Zhu Yang , Tian Shu , Xu Lan , Ma Yujie , Zhang Wenhao , Wang Lifeng , Jin Lina , Liu Chuanxu , Zhu Chuanying , Li Zhichao , Hao Siguo , Zhong Hua , Ding Hao , Tao Rong 
Published: November 2021

SummaryEarly‐stage natural killer/T‐cell lymphoma (NK/TCL) patients usually receive a combination of chemotherapy and radiotherapy, but the optimal treatment approach has not yet been established. This study aimed to investigate the efficacy and safety profile of a novel chemotherapy regimen and sandwiched radiotherapy in early‐stage NK/TCL. Patients with newly diagnosed stage IE/IIE disease were eligible. Patients were initially treated with two courses of the GELAD regimen (gemcitabine 1·0 g/m2 day 1, etoposide 60 mg/m2 days 1–3, pegaspargase 2000 units/m2 day 4, and dexamethasone 40 mg days 1–4), followed by intensity‐modulated radiotherapy (IMRT; 50–56 Gy in 25–28 fractions) and two additional courses of GELAD chemotherapy. A total of 52 patients were enrolled. The overall response rate and complete response rate per Lugano 2014 criteria were 94·2% and 92·3% respectively. With a median follow‐up of 32 months, the estimated four‐year overall survival rate and progression‐free survival rate were 94·2% [95% confidence interval (CI), 83·2% to 93·1%] and 90·4% (95% CI, 78·4% to 95·9%) respectively. The most common adverse events were related to pegaspargase. Haematological toxicities were mild, with grade 3/4 neutropenia in 15·4% of patients. Our study provides a new approach with high activity and improved safety for the treatment of early‐stage NK/TCL patients. This study was registered at www.clinicaltrials.gov as NCT02733458.
Parents experiences of having an infant with early onset group B streptococcus infection
Authors: McLeod Emma , Mason Celia , Swainston Katherine 
Published: November 2021

ObjectivesThe study explores parents lived experience of having an infant with early onset group B streptococcus (GBS).DesignThe study adopts a qualitative approach and a phenomenological framework with written autobiographical accounts as the method of data collection.MethodsTwenty‐seven parents wrote first‐hand accounts of their experience of having an infant with early onset GBS. Participants documented their experiences in their own way, reporting their thoughts and feelings, experiences, and events that were meaningful to them.ResultsFour themes were developed from data analysis: ‘bonding’; ‘grief’; ‘communication and information provision’; and ‘future family’.ConclusionsThe study findings demonstrate the complexity of emotions within parent’s experiences and highlight grief and loss as a core component of these experiences. Medical intervention, while acknowledged as being vital and in many cases lifesaving, was viewed as a disruption to early bonding experiences resulting in sadness and guilt. Variation in information provision, communication about this infection, and feeling that their infant’s illness and/or death were preventable added to the sense of loss. Breakdowns in interpersonal communications with partners and family were commonly described and experiences of early onset GBS had implications for decision‐making around future pregnancies.
Insecticide‐contaminated honeydew: risks for beneficial insects
Authors: Calvo‐Agudo Miguel , Tooker John F. , Dicke Marcel , Tena Alejandro 
Published: November 2021

ABSTRACTHoneydew is the sugar‐rich excretion of phloem‐feeding hemipteran insects such as aphids, mealybugs, whiteflies, and psyllids, and can be a main carbohydrate source for beneficial insects in some ecosystems. Recent research has revealed that water‐soluble, systemic insecticides contaminate honeydew excreted by hemipterans that feed on plants treated with these insecticides. This contaminated honeydew can be toxic to beneficial insects, such as pollinators, parasitic wasps and generalist predators that feed on it. This route of exposure has now been demonstrated in three plant species, for five systemic insecticides and four hemipteran species; therefore, we expect this route to be widely available in some ecosystems. In this perspective paper, we highlight the importance of this route of exposure by exploring: (i) potential pathways through which honeydew might be contaminated with insecticides; (ii) hemipteran families that are more likely to excrete contaminated honeydew; and (iii) systemic insecticides with different modes of action that might contaminate honeydew through the plant. Furthermore, we analyse several model scenarios in Europe and/or the USA where contaminated honeydew could be problematic for beneficial organisms that feed on this ubiquitous carbohydrate source. Finally, we explain why this route of exposure might be important when exotic, invasive, honeydew‐producing species are treated with systemic insecticides. Overall, this review opens a new area of research in the field of ecotoxicology to understand how insecticides can reach non‐target beneficial insects. In addition, we aim to shed light on potential undescribed causes of insect declines in ecosystems where honeydew is an important carbohydrate source for insects, and advocate for this route of exposure to be included in future environmental risk assessments.
Inequality in access to dental services in a market‐based dental care system: A population study from Norway 1975–2018
Authors: Jiang Nan , Grytten Jostein , Kinge Jonas Minet 
Published: November 2021

AbstractObjectiveTo examine income‐related inequalities in access to dental services from 1975 to 2018. In Norway, dental care services for adults are privately financed. This may lead to income‐related inequalities in access. In the early 1970s, that is, at the beginning of the study period, there were marked inequalities in access to dental services according to personal income. However, from the beginning of the 1970s, there has been a large increase in gross national income per capita in Norway as a result of the growth of the oil and gas industry. This increase in income also meant that people with a low income in 1975 had a rise in their level of income. According to the law of diminishing utility, an increase in income leads to higher consumption of dental services for people with a low level of income compared to people with a high level of income. The study hypothesis is that the inequalities in access to dental services that existed in 1975 became less over time.MethodsStatistics Norway collected samples of cross‐sectional health survey data for the following years: 1975, 1985, 1995, 2002, 2008, 2012 and 2018. For each sample, individuals 21 years and older were drawn randomly from the non‐institutionalized adult population using a two‐stage stratified cluster sample technique. Inequalities were measured using the concentration index. The dependent variable was the use of dental services during the last year, and the key independent variable was equivalized household income.ResultsThe concentration index for inequalities in use of dental services according to income decreased from 0.10 (95% CI = 0.09, 0.11) in 1975 to 0.04 (95% CI = 0.03, 0.05) in 2018. The decrease was particularly large from 2002 to 2012. This was a period with a large growth in gross national income.ConclusionPeople with a low income had a marked increase in their purchasing power from 1975 to 2018. This coincided with an increase in demand for dental care for this low‐income group.