bluuebunny/crossref_metadata_2025_split huggingface dataset:
Robust Segmentation of Cellular Ultrastructure on Sparsely Labeled 3D Electron Microscopy Images using Deep Learning
Authors: Machireddy Archana , Thibault Guillaume , Loftis Kevin G. , Stoltz Kevin , Bueno Cecilia E. , Smith Hannah R. , Riesterer Jessica L. , Gray Joe W. , Song Xubo 
Published: May 2021

SummaryA deeper understanding of the cellular and subcellular organization of tumor cells and their interactions with the tumor microenvironment will shed light on how cancer evolves and guide effective therapy choices. Electron microscopy (EM) images can provide detailed view of the cellular ultrastructure and are being generated at an ever-increasing rate. However, the bottleneck in their analysis is the delineation of the cellular structures to enable interpretable rendering. We have mitigated this limitation by using deep learning, specifically, the ResUNet architecture, to segment cells and subcellular ultrastructure. Our initial prototype focuses on segmenting nuclei and nucleoli in 3D FIB-SEM images of tumor biopsies obtained from patients with metastatic breast and pancreatic cancers. Trained with sparse manual labels, our method results in accurate segmentation of nuclei and nucleoli with best Dice score of 0.99 and 0.98 respectively. This method can be extended to other cellular structures, enabling deeper analysis of inter- and intracellular state and interactions.
XANES reflects coordination change and underlying surface disorder of zinc adsorbed to silica
Authors: Nelson Joey 
Published: May 2021

Zinc K-edge X-ray absorption near-edge structure (XANES) spectroscopy of Zn adsorbed to silica and Zn-bearing minerals, salts and solutions was conducted to explore how XANES spectra reflect coordination environment and disorder in the surface to which a metal ion is sorbed. Specifically, XANES spectra for five distinct Zn adsorption complexes (Znads) on quartz and amorphous silica [SiO2(am)] are presented from the Zn–water–silica surface system: outer-sphere octahedral Znads on quartz, inner-sphere octahedral Znads on quartz, inner-sphere tetrahedral Znads on quartz, inner-sphere octahedral Znads on SiO2(am) and inner-sphere tetrahedral Znads on SiO2(am). XANES spectral analysis of these complexes on quartz versus SiO2(am) reveals that normalized peak absorbance and K-edge energy position generally decrease with increasing surface disorder and decreasing Zn–O coordination. On quartz, the absorption-edge energy of Znads ranges from 9663.0 to 9664.1 eV for samples dominated by tetrahedrally versus octahedrally coordinated species, respectively. On SiO2(am), the absorption-edge energy of Znads ranges from 9662.3 to 9663.4 eV for samples dominated by tetrahedrally versus octahedrally coordinated species, respectively. On both silica substrates, octahedral Znads presents a single K-edge peak feature, whereas tetrahedral Znads presents two absorbance features. The energy space between the two absorbance peak features of the XANES K-edge of tetrahedral Znads is 2.4 eV for Zn on quartz and 3.2 eV for Zn on SiO2(am). Linear combination fitting of samples with a mixture of Znads complex types demonstrates that the XANES spectra of octahedral and tetrahedral Znads on silica are distinct enough for quantitative identification. These results suggest caution when deciphering Zn speciation in natural samples via linear combination approaches using a single Znads standard to represent sorption on a particular mineral surface. Correlation between XANES spectral features and prior extended X-ray absorption fine structure (EXAFS) derived coordination environments for these Znads on silica samples provides insight into Zn speciation in natural systems with XANES compatible Zn concentrations too low for EXAFS analysis.
Designing food experiences for well-being: a framework advancing design thinking research from a customer experience perspective
Authors: Batat Wided , Addis Michela 
Published: May 2021

Purpose
Literature from across design studies and innovation management, as well as food marketing research evidence, is examined to highlight the interdisciplinary and experiential research approaches to food consumption and well-being. This conceptual paper aims to address the need to expand the food industry’s goals by considering its contributions to the consumer’s overall food well-being. Food experience design (FED) seeks to understand how food professionals can design healthy and pleasurable food experiences aimed at enhancing people’s food well-being. FED does so by proposing a holistic and integrative framework.

Design/methodology/approach
This approach examines design thinking by conducting an analysis of the multidisciplinary literature. This paper addresses the gap in the literature by advancing the theoretical and empirical understanding of food design thinking through the lenses of experiential theory and consumer well-being.

Findings
This review paper clarifies the scope of FED scholarship and offers a call for collective efforts to establish a focused body of knowledge that leads food marketing professionals and scholars to adopt an experiential perspective to food consumption and production focused on experiential pleasure of food as a driving force for consumer’s well-being.

Research limitations/implications
The review paper addresses the need to expand the food industry’s goals by considering its contributions to the consumer’s overall food well-being. FED seeks to understand how food professionals can design healthy and pleasurable food experiences aimed at enhancing people’s food well-being. FED does so by proposing a holistic and integrative framework.

Practical implications
This research provides designers with the operative tools to create innovative food experiences and increase the food well-being of consumers. Toward that end, designers need to extend their skills and evolve their language and competencies to create valuable dialogues with other stakeholders involved. Collaboration requires many other premises. This paper contributes to the discussion by identifying and clarifying them.

Originality/value
This research highlights the imperative to take multidisciplinary, transformative and experiential approaches to researching food innovation strategies from a consumer’s well-being perspective.
Challenges in combatting female genital mutilation: narratives of black Sub-Saharan African (BSSA) women in the English west Midlands region
Authors: Nyashanu Mathew , Mguni Maureen 
Published: May 2021

Purpose
It is believed that more than 120 million women have undergone female genital mutilation (FGM) and more than 2 million young girls are at risk of undergoing FGM. FGM is practiced in different parts of the world. With globalisation and the increased movement of people across the globe, FGM is now a global problem. While ending FGM remains a priority, the approaches and strategies being used have generated contested views across the social divide. The purpose of this study is to explore the challenges in combatting FGM as experienced by Black Sub-Saharan African (BSSA) women in Diaspora.

Design/methodology/approach
This qualitative study used a phenomenological approach. Narratives were collected from 40 BSSA women from 20 Sub-Saharan African countries living in the English West Midlands region. A thematic approach underpinned by the four phases of data analysis in the Silences Framework were used to analyse the data.

Findings
The research study found that stigmatisation of survivors, utilisation of graphic images in FGM awareness, exclusion of practising communities’ gatekeepers in FGM interventions, conflation of religion and FGM practice and obsession with securing a conviction were obstacles in combating FGM. Diaspora community-driven studies exploring FGM and contested notions in addressing it from women perspectives are scarce.

Originality/value
This study pulls together the experiences of BSSA women and their perspectives on contested notions in combating FGM in the UK. The debate asserts the growing need to consider gender sensitive radical interventions, which involves educating perpetrators and gatekeepers among FGM practising communities.
Response measures to COVID-19 in prisons and other detention centers
Authors: Alves da Costa Filipa , Neufeld Maria , Hamad Mohamed , Carlin Eric , Ferreira-Borges Carina 
Published: May 2021

Purpose
The purpose of this paper is to summarize activities being undertaken by the World Health Organization (WHO) Regional Office for Europe to prevent and control COVID-19 in and beyond prisons, activities specifically designed to increase information sharing and to support Member States, to comment on potential impacts of these initiatives at country-level responses and to underline the need for a rights-based approach to managing the pandemic, including the right to vaccination.

Design/methodology/approach
The Health in Prisons Programme (HIPP) of the WHO Regional Office for Europe worked with partner organizations to review regularly the evidence on best practices in prison health and use it to inform policy recommendations at the global level. HIPP issued overarching guidance and specific tools to support implementation of measures to prevent and control the spread of COVID-19 in prisons and other custodial settings. Moreover, to monitor the emergence of outbreaks, the HIPP developed a minimum data set for countries voluntarily to report COVID-19 cases and identify situations in need of direct support.

Findings
Since May 2020, the WHO has periodically received data from Member States, leading to the development of country-specific bulletins to support countries and, whenever appropriate, to organize virtual missions to further support ministries and public health bodies responsible for managing COVID-19 in prisons.

Originality/value
The development of a specific set of indicators for prisons enables exploring data in a disaggregated manner. Monitoring response measures developed in prison enables judging their appropriateness to minimize the spread of SARS-CoV2 in prisons and alignment with guidance issued by the WHO.
Predictive power of training design on employee performance: an empirical approach in Pakistan's health sector
Authors: Bhatti Mitho Khan , Soomro Bahadur Ali , Shah Naimatullah 
Published: May 2021

PurposeThe purpose of this study is to ascertain the role of training design on employee performance in the health sector of Pakistan.Design/methodology/approachThis cross-sectional study applies random sampling to select respondents among Pakistan's trained health nurses. The study uses a survey questionnaire as a primary tool to collect the data. The 306 completed questionnaires form the study sample, with their data analyzed to find the results.FindingsStructural equation modeling shows the positive and significant roles of training content and learning style on employee performance. In contrast, the study finds the role of the trainer on nurses' employee performance in Pakistan to be insignificant.Practical implicationsThis research generally makes a valuable contribution to the training literature, particularly in Pakistan. Employers need to provide more training programs to reduce the cost of recruiting and training new staff members. Furthermore, the study recommends the provision of feedback to employees after training so they become aware of areas where they can improve their performance. This study's findings warrant consideration in the current training and development environment, and by policymakers and health sector planners of the Pakistani government.Originality/valueThis research study will help researchers to fill the gap in the international investigation by testing the training design and performance factors.
Pricing contract design of a multi-supplier-multi-retailer supply chain in hybrid electricity market
Authors: Zhu Zhenning , Kong Lingcheng , Aisaiti Gulizhaer , Song Mingzhen , Mi Zefeng 
Published: May 2021

PurposeIn the hybrid electricity market consisting of renewable and conventional energy, the generation output of renewable power is uncertain because of its intermittency, and the power market demand is also fluctuant. Meanwhile, there is fierce competition among power producers in the power supply market and retailers in the demand market after deregulation, which increases the difficulty of renewable energy power grid-connection. To promote grid-connection of renewable energy power in the hybrid electricity market, the authors construct different contract decision-making models in the “many-to-many” hybrid power supply chain to explore the pricing strategy of renewable energy power grid-connecting.Design/methodology/approachConsidering the dual-uncertainty of renewable energy power output and electricity market demand, the authors construct different decision-making models of wholesale price contract and revenue-sharing contract to compare and optimize grid-connecting pricing, respectively, to maximize the profits of different participants in the hybrid power supply chain. Besides, the authors set different parameters in the models to explore the influence of competition intensity, government subsidies, etc. on power pricing. Then, a numerical simulation is carried out, they verify the existence of the equilibrium solutions satisfying the supply chain coordination, compare the differences of pricing contracts and further analyze the variation characteristics of optimal contract parameters and their interaction relations.FindingsRevenue-sharing contract can increase the quantity of green power grid-connection and realize benefits Pareto improvement of all parties in hybrid power supply chain. The competition intensity both of power supply and demand market will have an impact on the sharing ratio, and the increase of competition intensity results in a reduction of power supply chain coordination pressure. The power contract price, spot price and selling price have all been reduced with the increase of the sharing ratio, and the price of renewable power is more sensitive to the ratio change. The sharing ratio shows a downward trend with the increase of government green power subsidies.Originality/valueOn the basis of expanding the definition of hybrid power market and the theory of newsvendor model, considering the dual-uncertainty of green power generation output and electricity market demand, this paper builds and compares different contract decision-making models to study the grid-connection pricing strategy of renewable energy power. And as an extension of supply chain structure types and management, the authors build a “many-to-many” power supply chain structure model and analyze the impact of competition intensity among power enterprises and the government subsidy on the power grid-connecting pricing.
Researcher attitudes toward data sharing in public data repositories: a meta-evaluation of studies on researcher data sharing
Authors: Thoegersen Jennifer L. , Borlund Pia 
Published: May 2021

PurposeThe purpose of this paper is to report a study of how research literature addresses researchers' attitudes toward data repository use. In particular, the authors are interested in how the term data sharing is defined, how data repository use is reported and whether there is need for greater clarity and specificity of terminology.Design/methodology/approachTo study how the literature addresses researcher data repository use, relevant studies were identified by searching Library Information Science and Technology Abstracts, Library and Information Science Source, Thomas Reuters' Web of Science Core Collection and Scopus. A total of 62 studies were identified for inclusion in this meta-evaluation.FindingsThe study shows a need for greater clarity and consistency in the use of the term data sharing in future studies to better understand the phenomenon and allow for cross-study comparisons. Furthermore, most studies did not address data repository use specifically. In most analyzed studies, it was not possible to segregate results relating to sharing via public data repositories from other types of sharing. When sharing in public repositories was mentioned, the prevalence of repository use varied significantly.Originality/valueResearchers' data sharing is of great interest to library and information science research and practice to inform academic libraries that are implementing data services to support these researchers. This study explores how the literature approaches this issue, especially the use of data repositories, the use of which is strongly encouraged. This paper identifies the potential for additional study focused on this area.
The USA–China trade policy uncertainty and inference for the major global south indexes
Authors: Akdag Saffet , Yildirim Hakan , Alola Andrew Adewale 
Published: May 2021

PurposeThe recent dynamics of trade policy, especially that is associated with the United States of America (USA) and China, has not only triggered policy adjustments in two economies, it has also implied an uncertainty spillover to other economies across the globe. Consequently, the current study attempts to examine the effect of uncertainties in the USA–China trade policies on stock market indexes. In addition, the cointegration evidence between the USA–China trade policy uncertainty index and of the leading Global South fragile quintet (Brazil, Indonesia, South Africa, India and Turkey) stock market indices is investigated.Design/methodology/approachMainly, the FMOLS and DOLS Granger causality analysis with cointegration coefficient estimators were employed for the dataset over the monthly data period of March 2003 and July 2019.FindingsAccordingly, the study found a long-term relationship between the USA–China Trade Policy Uncertainty index and the stock exchange indexes. In addition, a causal relationship was established from the change in the USA–China Trade Policy Uncertainty index to the change in the stock market indexes of almost all of the examined countries (Brazil, Indonesia, South Africa, India and Turkey). In addition, the nonlinear Autoregressive Distributed Lag approach further offers evidence of asymmetric relationship among the examined indicators.Originality/valueMoreover, this study contributed to the existing literature because it employed the indexes of BIST100, BOVESPA, BSE Sensex 30, IDX Composite and South Africa 40 in a novel approach. Thus, the study posited a useful policy guideline for associated economic uncertainties arising from the trade dispute, such as the case of the world’s two largest trading giants or partners (i.e. the USA and China).
Familiness and R&D investments
Authors: Damak Salma , Ben Mbarek Hela , Haj-Salem Issal 
Published: May 2021

PurposeThe purpose of this study is to investigate R&D investments in family firms.Design/methodology/approachThe socio-emotional wealth (SEW) perspective, considered as a dominant paradigm in the family business field, is the theoretical framework used to report different behaviors ascertained within family firms. This paper focuses on two dimensions of the SEW, namely, family control and influence and family identity. A suspected moderating role played by the firm’s life cycle stage on the dimensions is also investigated using panel data. To analyze the results, this paper uses the Smart PLS software on secondary data collected for 76 German family firms.FindingsThe empirical results reveal a negative influence of SEW on R&D investments. The prominent effect of the family control and influence dimension on R&D is higher in the first part of a firm life cycle.Research limitations/implicationsThe analysis of this study is subject to several caveats. First, to measure the R&D investment, this paper used R&D intensity computed as the total annual R&D expenses by total sales. Except for the fact that the use of proxies received several criticizes from scholars (Berroneet al., 2012) claiming how they do not directly relate to the essence of the dimensions measured. Second, this paper used two out of five FIBER dimensions only in the study. This paper took the right direction, but still, the complexity of SEW may not be fully captured following this approach (Berroneet al., 2012).Originality/valueThis study could be considered as an important extension of prior research investigating R&D in family firms. The authors provide a valid empirical construct, the FIBER scale, to capture non-monotonic behaviors in family firms and an enlargement of the family firms and innovation management field of research.
A causal model for health-related quality of life among Thai adolescents with congenital heart disease
Authors: Suratham Sathima , Prasopkittikun Tassanee , Srichantaranit Arunrat , Vongsirimas Nopporn 
Published: May 2021

PurposeThe objective of this study was to examine the causal relationships among sex, social support, disease severity, symptoms, physical activity, general health perception and health-related quality of life (HRQOL) in Thai adolescents with congenital heart disease (CHD).Design/methodology/approachA cross-sectional study was conducted using convenience sampling to recruit 200 Thai adolescents with CHD aged between 13 and18 years from four tertiary university hospitals in Bangkok. Interview method and self-administered questionnaires were used for data collection held between November 2018 and February 2019. Data were analyzed using path analysis to test the hypothesized model of the relationships.FindingsThe causal model of HRQOL revealed a good fit with the data. This model of relationship could explain 48% of the variances in HRQOL. Only direct effects of disease severity, symptoms and social support on HRQOL were found while indirect effects were not.Originality/valueDue to the lack of study focusing on factors influencing HRQOL in Thai adolescents with CHD, this empirical study provides the evidence in Thai literature. The modifiable influencing factors for HRQOL found in this study can be manipulated through psycho-educational intervention given to the adolescents and significant others, especially parents, to help increase quality of life in adolescents with CHD.
Educators’ experiences as K-12 students and efficacy for teaching in diverse schools
Authors: DeSantis Joshua , Christopher Cherish 
Published: May 2021

Purpose
Significant differences exist in the racial composition of America’s student and teacher populations. This reality is compounded by the racial re-segregation patterns affecting many schools and systems in the USA. These trends make it increasingly less likely that educators encounter racial diversity during their experiences as K-12 students and more likely that they encounter racial diversity as educators. This paper aims to present the results of a study designed to explore the consequences of this reality on those educators’ abilities to successfully reach their students?

Design/methodology/approach
The present study used a quantitative exploratory design. Data were analyzed to determine if educators’ experiences as K-12 students affected their present self-efficacy for teaching in diverse classrooms, their self-efficacy for using culturally responsive techniques, and their confidence in the merits of deploying these approaches in classrooms.

Findings
Data from the present study suggest that educators whose school experiences included significant interactions in racially diverse settings are significantly more likely to possess a higher level of self-efficacy than those who do not.

Originality/value
This study illuminates an unexplored consequence of school resegregation and lends support for efforts to diversify the teaching force and resist school resegregation.