bluuebunny/crossref_metadata_2025_split huggingface dataset:
Videos para mejorar las habilidades prácticas y conocimientos de cuidadores de pacientes con accidente cerebrovascular
Authors: Sánchez-Huamash Claudia María , Cárcamo-Cavagnaro César 
Published: May 2021

Objetivo: Evaluar el efecto de videos educativos para mejorar las habilidades prácticas y conocimientos de los cuidadores informales de pacientes con accidente cerebrovascular. Materiales y métodos: Estudio pretest/postest. Los participantes fueron diez cuidadores de 18 a 65 años y de ambos sexos de pacientes en fase subaguda del accidente cerebrovascular. Se desarrollaron ocho videos educativos relacionados aposicionamientos, movilizaciones y transferencias, que se implementaron en la casa de los cuidadores y/o pacientes a lo largo de tres días (en el primer día, tres videos; segundo día, tres videos; y tercer día, dos videos). Cada video fue visualizado en una tableta por 30 minutos. Las habilidades prácticas y conocimientos se evaluaron antes y después de cada video, y finalmente, la satisfacción de los cuidadores. Se usaron tres instrumentos, una lista de chequeo para evaluar las habilidades prácticas, un cuestionario para evaluar los conocimientos y otro para la satisfacción. Resultados: El puntaje de las habilidades prácticas incrementó de 21,6 a 56,1 puntos (p0,001) y los conocimientos de 11,6 a 21,6 puntos (p0,001). Además, 7/10 de los cuidadores estaban muy satisfechos con los videos, 7/10 consideró fácil las palabras, 7/10 consideró fácil poner en práctica las indicaciones, 9/10 definitivamente recomendaría los videos y todos los consideraban útiles. Conclusión: Los videos educativos mejoran las habilidades prácticas y conocimientos de los cuidadores informales de pacientes con accidente cerebrovascular. Los videos educativos desarrollados podrían usarse para capacitar a los cuidadores sobre el manejo de estos pacientes.
Bayesian Estimation of the ETAS Model for Earthquake Occurrences
Authors: Ross Gordon J. 
Published: May 2021

ABSTRACT
The epidemic-type aftershock sequence (ETAS) model is widely used in seismic forecasting. However, most studies of ETAS use point estimates for the model parameters, which ignores the inherent uncertainty that arises from estimating these from historical earthquake catalogs, resulting in misleadingly optimistic forecasts. In contrast, Bayesian statistics allows parameter uncertainty to be explicitly represented and fed into the forecast distribution. Despite its growing popularity in seismology, the application of Bayesian statistics to the ETAS model has been limited by the complex nature of the resulting posterior distribution, which makes it infeasible to apply to catalogs containing more than a few hundred earthquakes. To combat this, we develop a new framework for estimating the ETAS model in a fully Bayesian manner, which can be efficiently scaled up to large catalogs containing thousands of earthquakes. We also provide easy-to-use software that implements our method.
Investigation of the Performance of Simplified Constitutive Models in Nonlinear 1D Effective Stress Ground Response Analysis
Authors: Bessette Caroline , Yniesta Samuel 
Published: May 2021

ABSTRACTSeveral building codes, such as the National Building Code of Canada, recommend that an effective stress ground response analysis be performed if a liquefiable stratum is identified within a soil profile. Although, constitutive models for total stress ground response analysis have been well verified against earthquake recordings, existing models for effective stress ground response analysis have yet to be thoroughly validated. This article investigates the predictions of five pore pressure models derived for effective stress ground response analysis. First, a dataset of five downhole arrays and two centrifuge experiments in which a potential of liquefaction was identified is presented. The profiles and ground-motion recordings are selected to represent a broad range of soil properties, ground-motion intensities, and excess-pore pressure generation levels. The differences between predictions of the effective stress models against commonly used 1D ground response total stress equivalent-linear and nonlinear analyses are evaluated. The predicted and measured motions are compared in terms of spectral response and amplification factor. The pore pressure response of all models is evaluated as a function of shear strain and found to agree well with published correlations representing the expected behavior of liquefiable soils. Although, the models show the ability to capture liquefaction triggering, the results indicate that for the selected dataset, total stress simulations were found to be, at least, as precise and accurate as the effective stress simulations. Therefore, simplified models for effective stress ground analysis should be used with caution by practicing engineers to predict surface spectra but can be used confidently to assess the potential for liquefaction triggering.
Canonical Correlation Analysis Based on Site-Response Proxies to Predict Site-Specific Amplification Functions in Switzerland
Authors: Panzera Francesco , Bergamo Paolo , Fäh Donat 
Published: May 2021

ABSTRACTThe national seismic networks of Switzerland comprise more than 200 stations. At the station sites, the empirical amplification functions (EAFs) are routinely computed after each earthquake using a generalized inversion method based on separation of source, path, and site effects. The seismic stations are also characterized through geophysical measurements aiming to estimate shear-wave velocity profiles and horizontal-to-vertical spectral ratio of ambient vibrations (HVNR). Using this information, the correlation between the HVNR and EAF is assessed through canonical correlation. Once established, the canonical correlation is used to reconstruct the expected EAFpred at each considered station site in the dataset. The prediction is individually made for all seismic stations in the dataset, excluding every time the investigated station is from the calibration dataset; the reconstruction of the EAFpred is performed resorting to two parallel methods. The first method uses a combination of the canonical correlation parameters and Moran index, and the second one solves in a least-squares sense an overdetermined linear equation system including the canonical couples deemed as reliable. After a first round of predictions, a systematic lower EAFpred in soft sediment sites and a higher EAFpred in hard-rock sites is observed. A possible explanation for this behavior is found in the “normalization” to the Swiss standard rock profile in the computation of the EAF at the Swiss stations. Therefore, to reduce this effect, geological and geophysical parameters are considered in addition to the HVNR in the canonical correlation. We observe that the final solution improves when the least-squares solution approach is used with a combination of HVNR, VS30, and thickness of the ice cover at the last glacial maximum. Moreover, a blind test is performed using data not considered in the calibration dataset. The results highlight the ability of the method to provide an estimate of the site amplification over chosen frequency bins.
THE RELATIONSHIP BETWEEN THE SEVERITY OF MALOCCLUSION AND GINGIVAL STATUS IN STUDENTS OF SMPN 5 MARABAHAN
Authors: Ma’rifatullah Akhmad Aufayed , Wibowo Diana , Azizah Aulia 
Published: May 2021

ABSTRACTBackground: South Kalimantan experienced dental and mouth problems with a prevalence of 59,6%, so did Barito Kuala Regency with 68,66%. Malocclusion is a dental and oral health problem related to the disharmony between jaws and teeth. Many cases of malocclusion occur in children aged 12-14 years by 15,6% in the form of crowded teeth in South Kalimantan. Malocclusion is a factor that can cause food debris to stick to the interdental area between the crowded teeth, thus forming plaque accumulation. Plaque is the primary etiological factor that influences gingival status. Objective: This study aimed to determine the relationship between the severity of malocclusion and gingival status in students aged 12-14 years at SMPN 5 Marabahan. Method: This study used analytic survey research with cross sectional research design. The research population was all students of SMPN 5 Marabahan aged 12-14 years who born in March 2005 - January 2008, amounting to 88 people. The minimum sample size which determined by the proportion estimation formula was 47 people. The used sampling technique was simple random sampling technique with inclusion and exclusion criteria. Results: The distribution frequency of the study showed mild malocclusion of 55,3% and mild inflammation of 57,4%. Spearman analysis test results on the severity of malocclusion based on Mal I and gingival status based on GI showed a significance value of p = 0,045 (p < 0,05). Conlclusion: It could be concluded that there was a relationship between the severity of malocclusion and gingival status in students aged 12-14 years at SMPN 5 Marabahan.Keywords:Gingival Index, Gingival Status, Malalignment Index, Malocclusion, Permanent Tooth Occlusion Stage 2.
MANAGEMENT OF HSV-1 AND HSV-2 PRIMARY INFECTION IN ADULT PATIENT: A CASE REPORT
Authors: Kaban Bima Ewando , Riyanto Dahlia , Parmadiati Adiastuti , Radithia Desiana , Soebadi Bagus 
Published: May 2021

ABSTRACT Infection of Herpes Simplex Virus (HSV) type 1 and 2 causes medical problems throughout the world. HSV-1 infection often affects the oral regions and HSV-2 infection is the most prevalent cause of genital ulcerations. It is possible for HSV-2 to cause oro-labial herpes and HSV-1 to cause genital herpes. Primary HSV infection usually affects children or adolescent, whereas adults usually experience infection more frequently due to viral reactivation. Objective: To discuss the management of Primary HSV-1 and HSV-2 Infection which appears simultaneously in adults. Case report: a 33yearold female patient came to hospital with multiple painful ulcers in her tongue, buccal and labial mucosa, preceded by prodrome, followed with eruption and outbreak of vesicles on her skin. The first laboratory examination confirmed a high titer of reactive Immunoglobulin M (IgM) of anti-HSV-1 and Immunoglobulin M (IgM) anti-HSV-2. She was diagnosed to have Primary HSV-1 and HSV-2 Infection and treated with oral Acyclovir and Chlorine dioxide mouthwash with good healing. The clinical presentation, differential diagnosis and management of primary herpetic stomatitis are discussed. Conclusion: Correct diagnosis and treatment can restore well-being, avoid secondary problems for patients, and prevent the use of inappropriate drugs.Keywords : Herpes Simplex Virus, HSV-1, HSV-2, Management, Primary Herpes Infection
Strategi PIGELTIK Menuju Sekolah Adiwiyata di SMP Negeri 4 Bobotsari Purbalingga
Authors: Warsono Miswadi 
Published: May 2021

Strategi <em>PIGELTIK</em> Menuju Sekolah Adiwiyata di SMP Negeri 4 Bobotsari Purbalingga
Augmented Lateral Rectus Muscle Recession for treatment of Infantile Exotropia
Authors: Huang Lijuan , Li Ningdong 
Published: May 2021

Abstract
Background: For the majority of the patients, surgical treatment of primary infantile exotropia (PIE) with large exodeviation angels of more than 50 prism diopters (PD) is not satisfactory. We evaluate the effectiveness of augmented lateral rectus (LR) muscle recession in treatment of congenital exotropia with large deviation angles. Methods: A retrospective analysis was performed for 25 patients with congenital exotropia who had at least 60 prism diopters (PD). Augmented LR recession was performed using a hemi hang-back technique. The ocular alignment, ocular motility and binocular vision were evaluated pre- and postoperatively. Results: There were 14 male and 11 female affected individuals with congenital exotropia included in this study, with a mean age of (3.92±2.02) years (range, 1 - 7 years). The average exodeviation angle was (68.0±8.78) PD (range, 60 - 80 PD) preoperatively. All patients underwent bilateral LR recession, of whom 3 patients underwent bilateral inferior oblique muscle transposition in the same operation. The mean surgical dosage was (11.08±1.19) mm for each lateral rectus muclse. All patients did not have abduction deficiency after a large amount of lateral rectus recession. 21 of 25 patients (84.0%) acquired orthophoria at the primary gaze position at the final visit. 13 patients obtained binocular vision. Conclusions: Augmented bilateral LR recession is an effective and safe surgical procedure for treatment of congenital exotropia with large deviation angles.
Comparative analysis of latex transcriptomes reveals the potential mechanisms underlying rubber molecular weight variations between the Hevea brasiliensis clones RRIM600 and Reyan7-33-97
Authors: Xin Shichao , Hua Yuwei , Li Ji , Dai Xuemei , Yang Xianfeng , Udayabhanu Jinu , Huang Huasun , Huang Tiandai 
Published: May 2021

Abstract
Background: The processabilities and mechanical properties of natural rubber depend greatly on its molecular weight (MW) and molecular weight distribution (MWD). However, the mechanisms underlying the regulation of molecular weight during rubber biosynthesis remain unclear. Results: In the present study, we determined the MW and particle size of latex from 1-year-old virgin trees and 30-year-old regularly tapped trees of the Hevea clones Reyan7-33-97 and RRIM600. The results showed that both the MW and the particle size of latex varied between these two clones and increased with tree age. Latex from RRIM600 trees had a smaller average particle size than that from Reyan7-33-97 trees of the same age. In 1-year-old trees, the Reyan7-33-97 latex displayed a slightly higher MW than that of RRIM600, whereas in 30-year-old trees, the RRIM600 latex had a significantly higher MW than the Reyan7-33-97 latex. Comparative analysis of the transcriptome profiles indicated that the average rubber particle size is negatively correlated with the expression levels of rubber particle associated proteins, and that the high-MW traits of latex are closely correlated with the enhanced expression of isopentenyl pyrophosphate (IPP) monomer-generating pathway genes and downstream allylic diphosphate (APP) initiator-consuming non-rubber pathways. By bioinformatics analysis, we further identified a group of transcription factors that potentially regulate the biosynthesis of IPP. Conclusions: Altogether, our results revealed the potential regulatory mechanisms involving gene expression variations in IPP-generating pathways and the non-rubber isoprenoid pathways, which affect the ratios and contents of IPP and APP initiators, resulting in significant rubber MW variations among same-aged trees of the Hevea clones Reyan7-33-97 and RRIM600. Our findings provide a better understanding of rubber biosynthesis and lay the foundation for genetic improvement of rubber quality in H. brasiliensis.
The difference of lipid profiles between psoriasis with arthritis and psoriasis without arthritis and sex-specific downregulation of methotrexate on the apolipoprotein B/apolipoprotein A-1 ratio
Authors: Wang Bing , Deng Hui , Hu Yao , Han Ling , Huang Qiong , Fang Xu , Yang Ke , Wu Siyuan , Zheng Zhizhong , Nikhil Yawalkar , Zhang Zhenghua , Yan Kexiang 
Published: May 2021

Abstract
Background: Methotrexate (MTX) has a protective effect against cardiovascular diseases (CVD), but the mechanism is unclear.Objective: To investigate the effect of MTX on lipid profiles and the difference between psoriasis without arthritis (PsO) and psoriatic arthritis (PsA).Methods: In this prospective study, we recruited 288 psoriatic patients (136 PsA and 152 PsO) who completed 12 weeks of MTX treatment. Total cholesterol (TC), triglycerides (TG), lipoprotein A [LP(a)], high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein (LDL), apolipoprotein A1 (ApoA1), and ApoB were measured.Results: Compared with sex and age-matched healthy controls, psoriatic patients had significantly (p<0.0001) higher levels of proatherogenic lipids and lower levels of anti-atherogenic lipids. PsA patients had a higher ApoB/ApoA1 ratio than PsO patients(p<0.05). Stepwise regression analysis found a positive correlation between the inflammatory marker hCRP and the psoriasis area severiy index (PASI), ApoB/ApoA1 ratio, BMI, and smoking. ApoB was positively associated with concomitant arthritis, diabetes and hypertension. MTX decreased the levels of pro-atherogenic and anti-atherogenic lipids. However, a significant reduction of the ApoB/ApoA1 ratio by MTX was only observed in male patients.Conclusion: PsA patients had a significantly higher percentage of concomitant disease than PsO. The decrease of MTX on CVD might be related with sex.Trial Registration: ChiCTR2000036192
Subcortical Structures and Creative Divergent Thinking: A Resting-State functional MRI Analysis
Authors: Gao Zhenni , Liu Xiaojin , Zhang Delong , Liu Ming , Hao Ning 
Published: May 2021

Abstract
This study aimed to testify whether spontaneous fluctuations in the subcortex contribute to creative divergent thinking. Individuals at high- and low levels of creativity were recruited and the resting-state fMRI data was collected. Seed-wise and dynamic functional connectivity (FC) were used to identify differences between the two groups. The topological properties of the subcortical network were measured, and their relationship with performance of creative divergent thinking was calculated using brain-behaviour correlation analyses. The results revealed higher FC between the putamen, pallidum, and thalamus in high creativity group (HCG) compared to low creativity group (LCG) within the subcortex. Whole-brain FC results showed stronger connection across subcortical (i.e., the thalamus and pallidum) and cerebral regions (i.e., the insula, middle frontal gyrus, and middle temporal gyrus) in HCG compared to LCG. In addition, the subcortical FC demonstrated a positive correlation with performance of creative thinking across the pallidum, putamen, and thalamus. Our findings may provide novel insights into the relationship between creative divergent thinking and the activities of the subcortex. It is likely that not only fronto-striatal dopaminergic pathways, but also “motor” pathways, are involved in creative thinking processing.
Synthesis of Amid-MCM-41-SO3H Electrospun Nanofiber Mat: Candidate for Trapping of Microorganisms
Authors: Golshekan Mostafa , Hemmati Hossein , Ashoobi Mohammad Taghi , Asadi Khatereh 
Published: May 2021

Abstract
In the present study, amid-MCM-41-SO3H nano-composite is fabricated through the electrospinning process, which will a significant step toward air filtration for removal of microrganism from air particularly ICU hospital. The filtration mechanism of the amid-MCM-41-SO3H composite is based on the interaction of nanofiber functionalized group (-SO3H) with surface active groups of lipids and protein of microorganisms such as SARS-CoV-2. For the characterization of the synthesized nano-composite, various instrumentation methods were used. the SEM and TEM showed that the MCM-41- SO3H nanoparticles were uniformly distributed throughout the fiber length. Fourier Transform Infrared (FT-IR) spectroscopy confirms with the synthesized Amid-MCM-41-SO3H filter. X-ray Diffractometry (XRD) pattern indicated that the structure of the MCM-41-SO3H composite was well-preserved after modification. These results suggested that the amid-MCM-41-SO3H composite has higher performance in interaction with similar NPs of virus.
Impacts of soil and water conservation measures and slope position on selected soil attributes at a watershed scale
Authors: Retta Melaku Alene , Addis Hailu Kendie , Beyene Tesfaye Feyisa 
Published: May 2021

Abstract
Background: The Ethiopian highlands are affected by soil loss caused by soil erosion resulted in soil properties deterioration. To reverse this, different soil and water conservation (SWC) measures were spatially practiced; however, the effect of SWC and slope gradient on soil properties is not studied well in the area. Hence, this study was conducted to evaluate the effects of SWC and slope gradient on selected soil physicochemical properties at Dawnt watershed, North-western Ethiopia. The treatments were a combination of four different SWC measures with three slope gradients replicated at three sites. Disturbed and undisturbed soil samples were collected from 0-20cm soil depth and physicochemical properties were determined following standard laboratory procedures. Results: The lab results depict that sand, bulk density, moisture, particle density, porosity, pH, organic carbon (OC), cation exchange capacity (CEC), total nitrogen, and available phosphorus were significantly (P<0.05) affected by SWC measures and slope gradient. High OC (2.44%), CEC (45cmol (+) kg-1), and moisture (19.55%) were obtained from Stone-Faced Soil Bund stabilized with Grass (SFSBG) and high available phosphorus (7.83ppm) from Soil Bund (SB) while lower bulk density (1.13gm/cm3) from SFSBG. Additionally, higher clay (41.67%) and moisture (19.81%) and lower bulk density (1.14g/cm3) were obtained from the lower slope. Higher pH (6.75) and OC (2.89%) were recorded at lower slope under SFSBG and lower pH and OC (6.03 and 1.02%) at the upper slope with non-conserved. Soil chemical properties, except available potassium, were increased down the slope.﻿Conclusion: The interactions of slope position and SWC measures affect soil texture; pH, organic carbon, and available phosphorus but do not affect soil bulk density, moisture content, particle density, total porosity, cation exchange capacity, total nitrogen, and available potassium. In generally, the soil properties were improved through integrating conservation practices with multipurpose grass species across the study watershed. Therefore, in the study watershed and other similar agro-ecologies, farmers should use integrated SWC measures to avert the rainfall-driven soil nutrient loss.
Cannabidiol and refractory epilepsy: parental and caregiver perspectives of participation in a compassionate access scheme
Authors: Harte Suzanne , Singh Yeeshu , Malone Stephen , Heussler Helen , Wallace Geoffrey 
Published: May 2021

Abstract
Background The Compassionate Access Scheme (CAS) being delivered through the Queensland Children’s Hospital is designed to allow access to an investigational purified Cannabidiol oral solution to paediatric patients with severe refractory epilepsy. The objectives of this study were to conduct semi-structured interviews to: 1. Understand families’ expectations and attitudes about the use of an investigational cannabinoid product for their child’s seizures; 2. Understand families’ perceptions of Cannabidiol’s efficacy for their child’s seizures; and other aspects of their child’s behaviour, quality of life and/or cognition.Methods Children aged 2-18 years had been enrolled in, or were enrolled in a compassionate access scheme for Cannabidiol at the time of the study. Semi-structured interviews (n=19) with parents or caregivers (n=23) of children diagnosed with refractory epilepsy were voice-recorded, transcribed and analysed to generate common themes.Results Key themes emerged relating to seizure activity, family and school engagement, drug safety and legal access, efficacy, clinical support, social acceptance of the medication and program delivery. The use of Cannabidiol was perceived to have benefits in relation to reducing the severity and frequency of seizure activity for some, but not all patients experiencing refractory epilepsy. For other patients, benefits included improved social engagement, wakefulness and a reduction of side effects related to a reduction of conventional medication dosage.Conclusion This study provided unique perspectives of families’ experiences managing untreatable epilepsy, their experiences with conventional and experimental pharmacological treatments and health services. Whilst families’ perceptions showed the use of Cannabidiol did not provide a therapeutic reduction in the seizure activity for all patients diagnosed with refractory epilepsy, it’s use as an additional pharmacological agent was perceived to provide other benefits by some patient families.