bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evidence for equilibrium exciton condensation in monolayer WTe2
Authors: Sun Bosong , Zhao Wenjin , Palomaki Tauno , Fei Zaiyao , Runburg Elliott , Malinowski Paul , Huang Xiong , Cenker John , Cui Yong-Tao , Chu Jiun-Haw , Xu Xiaodong , Ataei S. Samaneh , Varsano Daniele , Palummo Maurizia , Molinari Elisa , Rontani Massimo , Cobden David H. 
Published: December 2021

AbstractWe present evidence that the two-dimensional bulk of monolayer WTe2 contains electrons and holes bound by Coulomb attraction—excitons—that spontaneously form in thermal equilibrium. On cooling from room temperature to 100 K, the conductivity develops a V-shaped dependence on electrostatic doping, while the chemical potential develops a step at the neutral point. These features are much sharper than is possible in an independent-electron picture, but they can be accounted for if electrons and holes interact strongly and are paired in equilibrium. Our calculations from first principles show that the exciton binding energy is larger than 100 meV and the radius as small as 4 nm, explaining their formation at high temperature and doping levels. Below 100 K, more strongly insulating behaviour is seen, suggesting that a charge-ordered state forms. The observed absence of charge density waves in this state is surprising within an excitonic insulator picture, but we show that it can be explained by the symmetries of the exciton wavefunction. Therefore, in addition to being a topological insulator, monolayer WTe2 exhibits strong correlations over a wide temperature range.
A commentary on the paper: ‘Evaluation of spice and herb as phytoderived selective modulators of human retinaldehyde dehydrogenases using a simple in vitro method’
Authors: Bilska-Wilkosz Anna 
Published: December 2021

Abstract
It is commonly known that aldehyde dehydrogenases (ALDHs) are a promising therapeutic target in many diseases. Bui et al.—the authors of the paper I am discussing here (Biosci Rep (2021) 41(5): BSR20210491 https://doi.org/10.1042/BSR20210491)—point that there is a lack of research on the use of spices and herbs as the sources of naturally occurring modulators of ALDH activity. In order to carry out this type of research, the authors prepared ethanolic extracts of 22 spices and herbs. The main objective of the study was to investigate retinaldehyde dehydrogenases (RALDHs), of which retinal is the main substrate and ALDH2, the mitochondrial isoform, having acetaldehyde as the main substrate.
The obtained results indicated that the tested extracts exhibited differential regulatory effects on RALDHs/ALDH2 and some of them showed a potential selective inhibition of the activity of RALDHs.
A Systematically Conducted Scoping Review of the Evidence and Fidelity of Treatments for Verb and Sentence Deficits in Aphasia: Sentence Treatments
Authors: Hickin Julie , Cruice Madeline , Dipper Lucy 
Published: December 2021

Purpose:
This review article synthesizes and evaluates the evidence for sentence production treatments in aphasia, systematically charting impairment-based and functional communication outcomes. It reports (a) the level of evidence and fidelity of sentence treatments; (b) the impact of treatment on production of trained and untrained verbs and sentences, functional communication, and discourse; and (c) the potential active ingredients of treatment.

Method:
The search included studies from January 1980 to June 2019. The level of evidence of each study was documented, as was fidelity in terms of treatment delivery, enactment, and receipt. Studies were also categorized according to treatment methods used.

Results:
Thirty-three studies were accepted into the review and predominantly constituted Level 4 evidence (e.g., case control studies and case series). Thirty studies (90%) described treatment in sufficient detail to allow replication, but dosage was poorly reported, and fidelity of treatment was rarely assessed. The most commonly reported treatment techniques were mapping (10 studies: 30%), predicate argument structure treatment (six studies: 18%), and verb network strengthening treatment (five studies: 15%). Production of trained sentences improved for 83% of participants, and improvements generalized to untrained sentences for 59% of participants. Functional communication was rarely assessed, but discourse production improved for 70% of participants.

Conclusions:
The evidence for sentence treatments is predominantly generated from Level 4 studies. Treatments were effective for the majority of participants regarding trained sentence and discourse production. However, there is inconsistent use of statistical analysis to verify improvements, and diverse outcome measures are used, which makes interpretation of the evidence difficult. The quality of sentence treatment research would be improved by agreeing a core set of outcome measures and extended by ascertaining the views of participants on sentence treatments.
Finite element design of a vibrational membrane to reduce distortion in a bone‐conduction implant transducer
Authors: Shin D. H. , Seong K. W. , Kim M. N. , Lee K. Y. 
Published: December 2021

AbstractThis paper describes the finite element design of a vibrational membrane with a cantilever structure to reduce distortion in bone conduction implant (BCI) transducers. To derive the optimal number of cantilevers, a model of ideally aligned components was established based on the structure of a previously proposed transducer, and mechanical vibration analysis was performed using different numbers of cantilevers (two to five). Under the same conditions, similar analyses were performed using vibrational membranes misaligned with the transducer magnet by 0.1 and 0.2 mm. Then, the standard deviations were calculated from the analysis results to numerically compare the magnitudes of vibrations between cantilevers for each cantilever shape. The larger the number of cantilevers, the smaller the standard deviation in both the alignment and misalignment cases. Moreover, from the analysis result, it was confirmed that using a vibrational membrane composed of five cantilevers can reduce distortion in BCI transducers.
Green preparation of nano‐silver aqueous solution using fructose and evaluation of its antibacterial potential for cut carnation flowers
Authors: Pang Zhenpei , Lin Guidong , Wu Yuheng , Li Hongmei , Sun Yunhao , Zhou Hongjun , He Shenggen 
Published: December 2021

AbstractThe green synthesis of nano‐silver (NS) has gained increasing attention owing to its cost‐effectiveness and environmental friendliness. Herein, a novel one‐step green preparation method of stable NS aqueous solution using Tollens reagent as the silver ion source, D‐fructose as the reduction agent, and polyvinyl pyrrolidone as the stabilizing and capping agent is reported. The prepared NS solution had a pH value of 7.10, with approximately spherical NS particles in the range of 13.95–87.36 nm. The resulting NS solution was stable under normal temperature, boiling water bath, and acidic environment. The NS solution had a remarkable absorption peak at 410 nm in its ultraviolet–visible spectrum. The dynamic light scattering/Zeta analysis showed the average particle size of the NS aqueous solution was 183.5 nm, polymer dispersion index was 0.282, and the zeta potential of the green synthesized NS was –18.0 mV. Moreover, the NS solution exerted a strong inhibitory effect on the growth of the bacteria isolated from the vase water of cut carnation ‘Prince’ flowers. These findings indicate that the obtained NS solution is potentially a practical and effective antibacterial agent for preserving cut carnations and other cut flowers.
Co‐optimization of active power curtailment, load shedding and spinning reserve deficits through hybrid approach: Comparison of electrochemical storage technologies
Authors: Nikolaidis Pavlos , Poullikkas Andreas 
Published: December 2021

AbstractUnder the constraints of fossil‐fuel reserves depletion and climate change, the expansion of intermittent renewable generation creates a lot of power integration issues which undeniably disturb the overall system stability. Optimally planned, electricity storage systems are capable of managing the variability and uncertainty of renewable energy sources, guaranteeing power balance and ensuring feasible and economical operation. Here, the outcomes derived by a Genetic algorithm‐driven priority list approach is provided, which effectively quantifies the impact of intermittent renewable energy sources on total production cost and the benefits of electricity storage. The experimental evaluation on three benchmark scenarios shows that cost improvements exist in terms of thermal generation improvement, lower renewable generation curtailment and load shedding avoidance cost. Zinc‐air battery offers the highest net present value at relatively low PV penetration levels. Increased penetration levels favour Li‐ion batteries followed by Pb‐acid and Vanadium‐redox flow batteries. In general, the viability of each storage device depends on the renewable penetration level, promoting the technologies with lower capital costs at limited shares, whereas at higher contribution frameworks systems with higher performance features become preferable.
Ablösung der In-Vitro-Diagnostika-Richtlinie auf die In-Vitro-Diagnostika-Verordnung (IVDR) 05/2022 und Programm für die BDDH-Veranstaltung im Rahmen des GTH-Kongresses 2022 in Leipzig
Authors: Sucker Christoph , Kappert Günther , Koscielny Jürgen 
Published: December 2021

Ablösung der In-Vitro-Diagnostika-Richtlinie auf die In-Vitro-Diagnostika-Verordnung (IVDR) 05/2022 (Christoph Sucker, Günther Kappert)
Planmäßig soll am 26.05.2022 die bisher geltende In-Vitro-Diagnostika-Richtlinie durch die In-Vitro-Diagnostika-Verordnung (IVDR) ersetzt werden und würde dann an diesem Tag unmittelbar rechtlich wirksam.
Therapie-Adhärenz bei Patient*innen mit Mukoviszidose im Erwachsenenalter
Authors: Kerscher Dirk , Hammer Sabine , Jung Michael 
Published: December 2021

Zusammenfassung
Hintergrund Um die Folgen der Progression von Mukoviszidose möglichst gering zu halten, benötigen Patient*innen ein Konzept für lebenslange medikamentöse Interventionen und intensive Physiotherapie, gepaart mit einer sehr hohen Therapie-Adhärenz. Durch die Erhöhung der durchschnittlichen Lebenswartung auf über 50 Jahre bei über der Hälfte der Betroffenen stehen medizinische Fachkräfte vor neuen Herausforderungen bei der Versorgung. Die nötigte Implementierung von Übergangsprogrammen für junge Erwachsene, aus den Kinderambulanzen heraus, sind jedoch noch immer nicht flächendeckend vollzogen. Niedrige Raten bei der Adhärenz verdeutlichen die problematische Situation.
Ziel Erfassung der Wahrnehmung von jungen Erwachsenen mit Mukoviszidose in Bezug auf Faktoren, die einen Einfluss auf ihre Therapie-Adhärenz haben.
Methode Das Erleben der Behandlungen sowie die Adhärenz beeinflussenden Faktoren wurden anhand von Leitfadeninterviews (n = 10) erhoben. Die Auswertung erfolgte mithilfe der inhaltlich strukturierenden Inhaltsanalyse nach Kuckartz.
Ergebnisse Es zeigt sich ein komplexes Gesamtbild von Einflussfaktoren, mit einem auffälligen Wechselverhalten zwischen Adhärenz und Non-Adhärenz zu medizinisch notwendigen Therapien. Aus Sicht der Befragten ist die partizipative Entscheidungsfindung der zentrale Ansatzpunkt zur Förderung der Adhärenz, Minderung des Wechselverhaltens und Stärkung der Bewältigung und Aufrechterhaltung von Selbstwirksamkeit.
Schlussfolgerung Die Ergebnisse geben Implikationen für die Ausbildung von Physiotherapeut*innen und Mediziner*innen bezüglich theoretischer Grundlagen zum Gesundheitsverhalten, zur Verhaltensänderung, Adhärenz und zu Entscheidungsprozessen von Patient*innen.
Modulating Autoimmunity against LDL: Development of a Vaccine against Atherosclerosis
Authors: Marchini Timoteo , Abogunloko Tijani , Wolf Dennis 
Published: December 2021

AbstractAtherosclerosis is a chronic inflammatory disease of the arterial wall that leads to the build-up of occluding atherosclerotic plaques. Its clinical sequelae, myocardial infarction and stroke, represent the most frequent causes of death worldwide. Atherosclerosis is a multifactorial pathology that involves traditional risk factors and chronic low-grade inflammation in the atherosclerotic plaque and systemically. This process is accompanied by a strong autoimmune response that involves autoreactive T cells in lymph nodes and atherosclerotic plaques, as well as autoantibodies that recognize low-density lipoprotein (LDL) and its main protein component apolipoprotein B (ApoB). In the past 60 years, numerous preclinical observations have suggested that immunomodulatory vaccination with LDL, ApoB, or its peptides has the potential to specifically dampen autoimmunity, enhance tolerance to atherosclerosis-specific antigens, and protect from experimental atherosclerosis in mouse models. Here, we summarize and discuss mechanisms, challenges, and therapeutic opportunities of immunomodulatory vaccination and other strategies to enhance protective immunity in atherosclerosis.
Influence of Sodium Hypochlorite and Chlorhexidine on the Dynamic Cyclic Fatigue Resistance of XP Endo Shaper Instruments
Authors: Tanomaru Alexandra Aparecida , Limoeiro Ana Grasiela , de Jesus Soares Adriana , Junior Elson Lopes Medeiros , Campos Gabriel Rocha , Hamasaki Sílvia Kaoru , Nascimento Wayne Martins , Horta Luiz Meton , Goulart Paula Avelar da Silva Ribeiro , do Couto Viviane Rangel , Alves Patrícia Bastos , Magalhães Verônica , Campos Danilo De Luca , Frozoni Marcos 
Published: December 2021

AbstractObjective This study evaluated the dynamic cyclic fatigue resistance of the XP-Endo Shaper (XPS), associated with chlorhexidine digluconate (CHX) or sodium hypochlorite (NaOCl) in two different formulations: gel (G) or liquid (L).Materials and Methods Sixty XPS were used in an artificial stainless-steel canal, and the files were fully immersed in the irrigating solution throughout the experiment until the fracture. The files were divided into six groups (n = 10) based on the irrigation solution used: NaOCl(L), NaOCl(G), CHX(L), CHX(G), natrosol gel (NAT) (control), and lubricating oil (LO) (control). The artificial canal was manufactured 1.5 mm wide, 20 mm long, and, 3.5 mm deep with a straight cervical segment measuring 14.29 mm; an apical segment of 4.71 mm with 3 mm radius; and 90 degrees of curvature apical 1 mm long straight segment. Resistance to cyclic fatigue was determined by recording the number of cycles to fracture (NCF).Results The CHX(G), CHX(L), and OIL (LO) groups showed no significant difference between them and presented longer time to fracture (p > 0.05). NaOCl(L) shows the lowest NCF without significant differences between NaOCl(G) and NAT. The NCF of the NaOCl(G) was statistically similar to the CHX(L) and statistically lower than the CHX(G) and OIL groups. NAT did not present a statistical difference of the NaOCl(L), NaOCl(G), and presented a significantly lower NCF than the CHX(G) (p < 0.01).Conclusion The use of CHX(G) resulted in increased cyclic fatigue resistance of the XPS instruments compared to NaOCl or LO.
Antifungal Activity of Beluntas “Indian Camphorweed” (Pluchea indica) Ethanol Extract on Candida albicans In Vitro Using Different Solvent Concentrations
Authors: Demolsky Wayan Larissa , Sugiaman Vinna Kurniawati , Pranata Natallia 
Published: December 2021

Abstract
Objective Oral candidiasis is an infection caused by pathogenic fungi Candida albicans, with a considerably high prevalence of 20 to 72%. Indian camphorweed (Pluchea indica) also known as “beluntas” as the local name has been known as a traditional medicine in Indonesia. The objective of this study is to research the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) of beluntas ethanolic extract against the growth of C. albicans.
Materials and Methods The MIC and MFC were measured by microdilution assay and total plate count respectively with a variation of solvents (DMSO 1%, 10%, and 4%) and beluntas extract with concentrations between 0.3125 and 200 mg/mL. Amphotericin and nystatin were used as a comparison.
Statistical Analysis One-way analysis of variance and posthoc Tukey test were used to determine the significant difference between treatments.
Results It was found that the MIC ranged from 50 to 200 mg/mL in the test with DMSO 10% solvent and MFC was found to be at a concentration of 200 mg/mL. However, there is a significant inhibitory effect and killing effect from DMSO 10% against C. albicans (p = 0.000). MIC was also found within concentrations of 100 mg/mL of beluntas extract in DMSO 4%. In this study, the DMSO 4% concentration neither showed significant inhibitory effects nor killing effects; therefore, the result was acceptable (p = 0.357).
Conclusion Ethanol extract of beluntas (P. Indica) has the potential of being an antifungal agent with inhibitory activity in concentrations ≥100 mg/mL, which is similar to nystatin (p = 0.278). The MFC for the extract was above 100 mg/mL, which cannot be measured with this method as a higher concentration of DMSO is needed, which had a toxic effect on the tested fungi.
Therapeutic IGF-I receptor inhibition alters fibrocyte immune phenotype in thyroid-associated ophthalmopathy
Authors: Fernando Roshini , Caldera Oshadi , Smith Terry J. 
Published: December 2021

SignificanceTeprotumumab, a therapeutic IGF-I receptor inhibitor, dramatically alters the clinical course of thyroid-associated ophthalmopathy (TAO) and has recently become the only medical therapy for TAO thus far approved by the US FDA. Introduction of teprotumumab has resulted in a paradigm shift in the clinical management of TAO. Here, we demonstrate that teprotumumab and other IGF-I inhibitors attenuate MHC II and B7 expression in fibrocytes in TAO, both in vitro and in patients treated with the drug in vivo. This inhibition is associated with substantial reductions in two key inflammatory cytokines implicated in TAO. Thus, the current findings provide a plausible mechanism underlying the therapeutic responses to teprotumumab.
Experimental amplitude and frequency control of a self-excited microcantilever by linear and nonlinear feedback
Authors: Higuchi Eisuke , Yabuno Hiroshi , Yamamoto Yasuyuki , Matsumoto Sohei 
Published: December 2021

Abstract
It is well known that the micro scale deviations of mechanical properties of a sample can be detected by measurement methods that use microcantilever as resonators. Those methods use the natural frequency shift of a resonator, thus we need to recognize the frequency shift caused by the effects of a sample on a resonator with high sensitivity and accuracy. Experimental approaches based on self-excited oscillation enable the detection of these shifts even when the resonator is immersed in a high-viscosity environment. In the present study, we experimentally and theoretically investigate the nonlinear characteristics of a microcantilever resonator and their control by nonlinear feedback. We show that the steady-state response amplitude and the corresponding response frequency can be controlled by cubic nonlinear velocity feedback and cubic nonlinear displacement feedback, respectively. Furthermore, the amplitude and frequency of the steady-state self-excited oscillation can be controlled separately. These results will expand application of measurement methods that use self-excited resonators.
Improving the accuracy of the neuroevolution machine learning potential for multi-component systems
Authors: Fan Zheyong 
Published: December 2021

Abstract
In a previous paper Fan et al (2021 Phys. Rev. B 104, 104309), we developed the neuroevolution potential (NEP), a framework of training neural network based machine-learning potentials using a natural evolution strategy and performing molecular dynamics (MD) simulations using the trained potentials. The atom-environment descriptor in NEP was constructed based on a set of radial and angular functions. For multi-component systems, all the radial functions between two atoms are multiplied by some fixed factors that depend on the types of the two atoms only. In this paper, we introduce an improved descriptor for multi-component systems, in which different radial functions are multiplied by different factors that are also optimized during the training process, and show that it can significantly improve the regression accuracy without increasing the computational cost in MD simulations.
Polarized light-aided visual-inertial navigation system: global heading measurements and graph optimization-based multi-sensor fusion
Authors: Xia Linlin , Liu Ruimin , Zhang Daochang , Zhang Jingjing 
Published: December 2021

Abstract
Polarized skylight is as fundamental a constituent of passive navigation as the geomagnetic field. With regard to its applicability to outdoor robot localization, a polarized light-aided visual-inertial navigation system (VINS) modelization dedicated to globally optimized pose estimation and heading correction is constructed. The combined system follows typical visual simultaneous localization and mapping (SLAM) frameworks, and we propose a methodology to fuse global heading measurements with visual and inertial information in a graph optimization-based estimator. With ideas of‘adding new attributes of graph vertices and creating heading error-encoded constraint edges’, the heading, as the absolute orientation reference, is estimated by the Berry polarization model and continuously updated in a graph structure. The formulized graph optimization process for multi-sensor fusion is simultaneously provided. In terms of campus road experiments on the Bulldog-CX robot platform, the results are compared against purely stereo camera-dependent and VINS Fusion frameworks, revealing that our design is substantially more accurate than others with both locally and globally consistent position and attitude estimates. As a passive and tightly coupled navigation mode, the polarized light-aided VINS can therefore be considered as a tool candidate for a class of visual SLAM-based multi-sensor fusion.
Information entropy, fractional revivals and Schrödinger equation with position-dependent mass
Authors: Iqbal Shahid 
Published: December 2021

Abstract
Information entropy has played a key role in a wide range of disciplines, for instance, classical and quantum information processing, quantum computing, quantum dynamics and quantum metrology. Here, we develop an information theoretic formalism using Shannon entropy, to investigate the quantum dynamics of Hamiltonian systems with position-dependent mass. Such systems are of fundamental interest in many areas, for instance, condensed matter, mathematical physics and foundations of quantum mechanics. We explore the phenomenon of fractional revivals for the temporal evolution of wave-packet solutions of Schrödinger equation with position-dependent mass by studying, analytically and numerically, the time-development of Shannon information entropy in position and momentum spaces. It is shown by our numerical results that the effect of spatially varying mass on the fractional revivals can not be fully harnessed using conventional measures, for instance, autocorrelation function. However, based on our numerical analysis it is concluded that information entropy is not only more sensitive to identify the fractional revivals but it also better elucidates the effect of position-dependent mass on the structure of fractional revivals in the form of symmetry breaking.