bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study On The Influence of Fiber Cutting Angle On Cutting Force In Ultrasonic Assisted Cutting CFRP Disc
Authors: Wang Xiaobo , Song Chaosheng , Li Lulu , Jiao Feng 
Published: December 2021

Abstract
Carbon fiber reinforced plastics (CFRP) is a new type of composite material that is widely used in the aviation field, the influence mechanism of fiber cutting angle on cutting force is analyzed, a theoretical model of ultrasonic assisted cutting force for CFRP is established, ultrasonic assisted longitudinal-torsional cutting experiments of CFRP disc are carried out, and compared with normal cutting process. According to the experimental results, the radar map of the cutting force along the circumference of CFRP unidirectional laminates is established, which show that the cutting force can be reduced by ultrasonic assisted cutting compared with ordinary cutting. Under the three cutting modes, the fiber cutting angle has a great influence on the tangential force, and the radial force of the same fiber cutting angle is less than the tangential force, the maximum radial force appeared near the fiber cutting angle of 120°, while the minimum tangential force and the minimum radial force both appear near the parallel direction cutting at 0°. The research results can be used for reference in the processing of CFRP and other composite materials.
Global Warming Signals in Brazil and its Macro-Regions - Trend Analysis of Distributional Characteristics Characteristics
Authors: Pellenz Jessica de Lima da Vida , de Mattos Leonardo Bornacki 
Published: December 2021

Abstract
The aim of this research is to study global warming signals across Brazil. This investigation uses approximately 60 years of daily temperature data set and applies a recent trend test proposed by Rivas and Gonzalo (2020) which analyses not only the average but also different distributional characteristics. Besides, the test provides robust results for both I(0) and I(1) processes. We found significant trends in almost all characteristics in the analysis of the whole country. The mean and the maximum are increasing over time and the dispersion measures indicate decreasing trends. For the region analysis, we found out that, apart from the South, which does not appear to be drastically affected by global warming, the other regions present clear signs of global warming.
Are cultural safety definitions culturally safe? A review of 42 cultural safety definitions in an Australian cultural concept soup
Authors: (Ngiyampaa) Mark Lock , (Wiradjuri) Megan Williams , (Saltwater Gomeroi) Atalanta Lloyd-Haynes , Burmeister Oliver , Came Heather , (Wiradjuri) Linda Deravin , Browne Jennifer , Alvarez Maria Jose Lopez , Yorta) Troy Walker (Yorta , Biles Jessica , (Barunggam) Danielle Manton , Randell-Moon Holly , Zaccone Sophie , Otmar Renée , Kendall Elizabeth , Flemington Tara , Hastings Aqua , (Wiradjuri) Jayne Lawrence , (Wiradjuri) Faye McMillan AM , (Gamilaraay) Bindi Bennett 
Published: December 2021

Abstract
Cultural safety is a keystone reform concept intended to improve First Nations Peoples’ health and wellbeing. Are definitions of cultural safety, in themselves, culturally safe? A purposive search of diverse sources in Australian identified 42 definitions of cultural safety. Structuration theory informed the analytical framework and was applied through an Indigenist methodology. Ten themes emerged from this analysis, indicating that cultural risk is embedded in cultural safety definitions that diminish (meddlesome modifications and discombobulating discourse), demean (developmentally dubious and validation vacillations), and disempower (professional prose, redundant reflexivity, and scholarly shenanigans) the cultural identity (problematic provenance and ostracised ontology) of First Nations Australians. We offer four guidelines for future definitional construction processes, and methodology and taxonomy for building consensus based of definitions of cultural safety. Using this approach could reduce cultural risk and contribute to improved workforce ability to respond to the cultural strengths of First Nations Australians.
Metformin significantly lowers the mortality rate in diabetic COVID-19 patients
Authors: Korkusuz Ramazan , Karandere Faruk , Okay Fatih , Koçoğlu Hakan 
Published: December 2021

Abstract
Introduction: This study evaluates the effect of glycemic control and anti-diabetic agents on the prognosis of diabetic COVID-19 patients. Method: The study includes diabetic patients who were treated and followed up in our hospital because of COVID-19 between 1 June 2020 and 1 January 2021. Patients with any additional comorbidity were excluded from the study. The demographic data of the patients, physical examination findings, laboratory tests, and radiological examination results were obtained retrospectively from the hospital records system.Results: A total of 207 diabetic patients consisted of 125 (60.4%) males and 82 (39.6%) females were included to this study. The mortality rate in cases using metformin was found to be statistically significantly lower than in cases using other drugs (p=0.016; p<0.05). No statistically significant difference was found between the HbA1c and glucose measurements of the cases according to mortality (p>0.05).Discussion: Metformin treatment in diabetic patients diagnosed with COVID-19 should not be stopped, other than in cases with severely hypoxic advanced stage chronic renal failure. Metformin can be recommended as a preventative drug to increase survival in diabetic patients with COVID-19. Nevertheless, there is a need for more evidence and more extensive studies to investigate the protective effects of metformin in COVID-19 patients and in similar viral infections.
Substance P/NK1R antagonistic effect of 17-Trifluoromethyl phenyl trinor prostaglandin F2α in Breast cancer
Authors: Mutukuru Mayuri , T.M Vijayakumar 
Published: December 2021

Abstract
17-Trifluoromethyl phenyl trinor prostaglandin F2α (17-TPGF2α) is extracted from Zinc data base, but its value for inhibiting breast cancer through SP/NK1R system remains unknown. This study was designed to investigate the potential antagonist effect of 17-TPGF2α through NK1Receptor. The effect of 17-TPGF2α on the proliferation and apoptosis of breast cancer cell lines were determined through invitro cell lines. Based on invitro results we planned to investigate anticancer activity in Female Balb/c and used SC injection of DMBA for cancer induction. Oral administration of 17-TPGF2α significantly suppress the tumor volume as compared with an untreated group. The serum parameters like ALP, AST and ALT and haematological parameters were normalized in test treated group. Histological examination revealed normal histoarchitecture of mammary gland and focal areas showed minimal inflammatory cell infiltration. There is no necrosis is seen both test treated and standard treated group when compared with Disease group. All these findings concluded that 17-TPGF2α may have potential as a novel antitumor candidate for breast cancer.
The Effect of Covid -19 Pandemic On Eye-Related Emergency Department Visits: A Comparison of Tertiary Eye Care Hospital Two -Year Results
Authors: Yılmaz Mevlüt , Ceylanoglu Kubra Serbest , Sen Emine Malkoc 
Published: December 2021

Abstract
Purpose: The aim of study is to examine the clinical and demographic impact of the Covid 19 pandemic on emergency department admissions to a tertiary eye care hospital.Methods: Records of admissions to the ophthalmology emergency department during a one-year period before the pandemic (group 1) and during the pandemic (group 2) were retrospectively reviewed between March 15, 2019, and March 15, 2021. Application numbers, demographic characteristics of patients were recorded. The cases were grouped by age and diagnosis, and the findings were compared within and between the groups. Results: A total of 161 941 patients (Group 1: 103 178 and Group 2: 58 763) were admitted to the emergency department of our hospital within 2 years. All admission diagnoses were significantly lower in the pandemic period than in the pre-pandemic period (p:0.001). However, the rate of sight-threatening cases or cases requiring urgent treatment (retinal diseases, uveitis, etc.) was significantly higher in the pandemic period than in the pre-pandemic period (p:0.001). The most common admission diagnoses were ocular infectious/inflammatory diseases while the foreign body on the ocular surface/ocular trauma group was second. Admissions for allergic and infectious diseases were significantly less during the pandemic period (p: 0.001, p: 0.002 respectively).Conclusion: The Covid 19 pandemic has led to significant changes in the application numbers, demographic features and reasons for admissions to the emergency department.
Gender Audit as Basis in Developing Modules for GAD Focal Persons in Mati, Davao Oriental, Philippines
Authors: Villegas Jhonnel 
Published: December 2021

Abstract
Many countries across the globe, including the Philippines, have implemented Gender and Development (GAD) policies to reduce gender biases and promote equality. However, mainstreaming efforts have been challenging due to the scarce availability of learning resources in the local context. This study is an initiative to provide the GAD Focal Point System (GFPS) in the Department of Education – City of Mati with a primary reference in training their GAD Focal Persons on Gender Sensitivity, GAD Planning, and Budgeting (GPB). The coverage is based on their learning needs and gaps determined through participatory strategies involving the school administrators, teachers, students, and parents. Also, the results of the gender audit using the Gender Mainstreaming Evaluation Framework (GMEF) are used as a baseline in module development. The framework presents strategic directions that agencies need to follow to advance across stages. It was found that Mati’s primary and secondary schools are in the initial stages of gender mainstreaming. As such, GAD’s basic concepts and definitions are introduced, along with various forms of gender-based violence and the appropriate mechanisms to address them aptly. The essential steps in planning and budgeting are also detailed, providing an active experience among the participants. It is imperative to sustain GAD capacity-building initiatives to catalyze a more directed and engaged policy framework.
Perceptions and key challenges towards sustainable condominium housing development in Gondar City, Ethiopia.
Authors: Bantayehu  
Published: December 2021

Abstract
Condominium houses were one of the housing typologies that differed in administration, shared resources, and activity delivered in the houses. The study focused on the perception of condominiums and the challenges of their sustainability. The researcher followed qualitative and quantitative research approaches in which 357 samples were taken through probability sampling techniques from a total of 3346 condominium residents. Primary data gathered through questionnaires, interviews, and observations, as well as secondary data gathered through document review, were combined and analyzed using SPSS version 20 and presented in a table and wordily with explanations. The finding shows that the residents have a positive perception of condominiums in social and cultural diversification, resource sharing, the accumulation of dry waste, accommodating social services and facilities, and reducing travel costs. On the other hand, they perceived that the quality of house, administration and management system of the resources, local community involvement and infrastructural integration were poor; areas of floor and corridor were not uniform and narrow; the cost and renting were high. The challenges to sustaining the condominium housing development were affordability, quality of the house, building and neighborhoods, cost variation, low loan return and administration system.
Assessment of Gas Hydrate Resources in Ross Sea Area, Antarctica Based on Inversion of Gravity and Magnetic Data
Authors: Wang wei , Wan meng , Sun miaojun , Jiang weijie , Xu ping 
Published: December 2021

Abstract
The Ross Sea is located between Victoria Land and Mary Bird Land in West Antarctica. In this paper, the published gravity and magnetic data in the Ross Sea area are fused with the high-precision gravity and magnetic data measured by the ship. Then, The gravity anomaly data is used to invert the Moho depth by the Parker-Oldenburg method; the magnetic anomaly data is used to invert the Curie depth of the Ross Sea area by the power spectrum method. Finally, according to the inversion results of the Moho depth and Curie depth, the high-precision heat flow distribution in the Ross Sea area is calculated. And compared with the actual measured heat flow value and other inversion results, it shows that this inversion result has obtained a higher resolution. At the same time, the geothermal gradient is calculated by heat flow and thermal conductivity. According to the temperature-pressure equation for formation and storage of gas hydrate, the thickness of the gas hydrate stability zone in the study area was quantitatively calculated.
A Probabilistic Trust Model for Cloud Services Using Bayesian Networks
Authors: Hosseinnezhad Mihan , Azgomi Mohammad Abdollahi , Dishabi Mohammad Reza Ebrahimi 
Published: December 2021

Abstract
With the rapid adoption of cloud computing in the industry, there has been a significant challenge in managing trust between cloud service providers and service consumers. In fact, trust management in cloud computing has become very challenging given the urgent need for cloud service requesters to choose efficient, trustworthy and non-risky services. One of the most important factors that can be considered in the trust or distrust of a service by the applicant is the different quality of services related to the service. Therefore, approaches are needed to assess the trustworthiness of cloud services with respect to the values ​​of their Quality of Service (QoS). Given the uncertainty that exists for cloud services, it is more realistic to model their QoS parameters as random variables and also consider different dependencies between them. In this paper, a new trust model for cloud services is proposed using Bayesian networks. Bayesian network is a probabilistic graphical model that can be used as one of the best methods to control uncertainty. Using Bayesian network makes it possible to infer more accurate QoS values ​​will which leads to the selection of highly trustworthy services by several cloud service requesters. The results of the experiments show that the proposed trust model is highly accurate and significantly reduces the estimation error.
Policy Spotlight Effect in Critical Time-Sensitive Diseases
Authors: Lin Chih-Yuan , Chang Li-Chuan , Lee Yue-Chune 
Published: December 2021

Abstract
Background: Categorization of hospital emergency capability (CHEC) is a policy implemented worldwide to regionalize critical emergent care. The CHEC policy mainly uses time-based indicators as emergency care quality measurements.Objectives: We aimed to explore the CHEC policy spotlight effect on critical time-sensitive diseases with and without the influence of time-based surveillance indicators and guidelines. Research Design: We conducted a nationwide retrospective cohort study between 2005–2011. Regarding critical time-sensitive diseases, our study targeted acute ischemic stroke (AIS), ST-segment elevation myocardial infarction (STEMI), septic shock, and major trauma. We selected diagnosis and treatment guideline adherence as process quality measures and defined medical utilization, upward transfer rate, and short-term mortality rate as outcome indicators. Subjects: The Taiwan National Health Insurance 2005 Longitudinal Health Insurance Database contains one million random cases, including medical records and hospital information. Results: During this 7-year study AIS, STEMI, septic shock, and major trauma, respectively. AIS and STEMI cohorts had significantly higher rates of guideline adherence and better process quality than those of septic shock and major trauma cohorts. Furthermore, AIS and STEMI cohorts had a significant increase in diagnosis costs. Conclusion: The CHEC policy spotlight effect exists in critical time-sensitive diseases with time-based quality indicators. Importantly, disease entities without these indicators may experience decreases in diagnosis and treatment guideline adherence, indirectly jeopardizing their outcomes.
Increased Peripheral Blood Eosinophils May Indicate Acute Infection in Neonates
Authors: Wang Weiying , Zhao Yuan , Yuan Bi-Fen 
Published: December 2021

Abstract
BackgroundEosinophils are now being recognized for more varied functions such as antiviral and bactericidal effects. This study aimed to explore the association between increased blood eosinophils and frequent pathogens due to the infections in children. Methods A total of 2353 children with acute infections admitted to Guangzhou Women and Children's Medical Center from February 1, 2019 to January 31, 2020 were enrolled in the study. 277 children without infections were comprised the control group. Children’s age, peripheral blood parameters including white blood cells, eosinophils, C-reactive protein (CRP) were recorded. In addition, infection stage and departments the patients admitted to were investigated. The study protocol was approved by the institutional ethics committee of the Guangzhou Women and Children's Medical Center (NO.2020110819342581).Results Blood eosinophil numbers negatively correlated with the age of children, whereas had no relation to disease stage. The means of eosinophil for neonates (<0.1 year)，infancy (<1year) and children >1year with acute infections were 0.67±0.40, 0.40±0.68, 0.15±0.25 *109/L compared with control group matched for age(0.44±0.20, 0.45±0.27, 0.24±0.19*109/L, P <0.001, <0.001, 0.497, respectively). Among them, the mean of eosinophil in the neonates afflicted with acute infections was significantly higher than the others compared to age-matched controls (0.63±0.60 vs 0.44±0.20, P= 0.012). Areas under the curves (AUC) were 0.81 (95% CI 0.75–0.86) for eosinophil combined with CRP and 0.68 (95% CI 0.61–0.75) for CRP alone for acute infections in neonates (P=0.02). Patients admitted in ICU had higher eosinophils than outpatients (0.46±0.60 vs 0.16±0.24, P <0.001) but had no significant difference compared with control group (0.45±0.20, P >0.99). Conclusion Increased peripheral blood eosinophils may indicate acute infections among neonates. Eosinophil combined with CRP can contribute to evaluating this population.
Increased Risk of Internal Tumors in DNA Repair-Deficient Xeroderma Pigmentosum Patients: Analysis of Four International Cohorts
Authors: Nikolaev Sergey , Yurchenko Andrey A. , Sarasin Alain 
Published: December 2021

Abstract
Background
Xeroderma pigmentosum (XP) is a rare, autosomal, recessive DNA repair-deficiency disorder with a frequency of 1-3 per million livebirths in Europe and USA but with higher frequencies in isolated islands or in countries with a high level of consanguinity. XP is characterized by high incidence of skin cancers on sun-exposed sites. Recent improvement in life expectancy of XP patients suggests an increased risk of frequently aggressive and lethal internal tumors. Our purpose was to quantify relative risks of internal tumor development for XP patients by tumor type, XP-subtype, patients’ ages and ethnicity through comparison with the US general population.
Methods
We analyzed four independent international well-characterized XP cohorts (from USA, UK, France and Brazil) with a total of 434 patients, where 11.3% developed internal tumors and compared them to the American general population. We also compiled, through PubMed/Medline, a dataset of 89 internal tumors in XP patients published between 1958 and 2020.
Results
In the combined 4-XP cohort, relative risk of internal tumors was 34 (95% confidence interval (CI) 25-47) times higher than in the general population (p-value=1.0E-47) and tumor arose 50 years earlier. The XP-C group was at the highest risk for the 0-20 years old-patients (OR=665; 95% CI 368-1200; p-value=4.3E-30). The highest risks were observed for tumors of central nervous system (OR=331; 95% CI 171-641; p-value=2.4E-20), hematological malignancies (OR=120; 95% CI 77-186; p-value=3.7E-36), thyroid (OR=74; 95% CI 31-179; p-value=1.2E-8) and gynecological tumors (OR=91; 95% CI 42-193; p-value=3.5E-12). The type of mutation on the XPC gene is associated with different classes of internal tumors. The majority of French XP-C patients (80%) are originated from North Africa and carried the XPC delTG founder mutation specific from the South Mediterranean area. The OR is extremely high for young (0-20 years) patients with more than 1,300-fold increase for the French XPs carrying the founder mutation.
Conclusion
Because the age of XP population is increasing due to better sun-protection and knowledge of the disease, these results are of particular importance for the physicians to help in early prevention and detection of internal tumors in their XP patients. Few preventive blood analyses or simple medical imaging may help to better detect early cancer appearance in this population.
Significance of Early Acidosis in Predicting Early Mortality Among Flame Burned Patients in a Kenyan National Hospital
Authors: Mackutwa Edward Nandi , Khainga Stanley Ominde , Ndung'u James Muturi , Anangwe Charles Okwemba 
Published: December 2021

Abstract
Background: Burn pathophysiology, fluid therapy and mortality have been assessed by various laboratory parameters including lactate and base deficit serum markers. This study targeted flame injured cohort with an objective to determine the significance of early acidosis, through measurement of three acid base indices at admission in predicting 5-day (early) mortality among the flame burned patients.Methodology: A cohort study. Eighty flame injured patients presenting within 24 hours of incident were assessed for arterial blood pH, lactate and base deficit (BD). Mortality was recorded until day 28. Receiver operating characteristics curves were drawn; area under curve, cut offs, sensitivities and specificities for BD, lactate and pH were determined for 5-day mortality. The cut offs were used to derive contingency tables for calculation of predictive values. Odds ratios were calculated at 95% confidence interval. 28 day survival curve was generated. Level of significance was <0.05.Results: 28-day mortality was 39%. Five-day mortality was 24%. The latter was predicted by a lactate level of 2.36 mmol/L, BD of -10.05 mmol/L and pH of 7.344 with 75%,74% and 95% sensitivities respectively. Odds of patients dying at these levels or worse were 6.3, 11.4 and 36.9 respectively all with significant p-values.Conclusion: Arterial pH, base deficit and lactate are good predictors of 5-day mortality among fire victims in the Kenyan context.