bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of Trochlear Dysplasia and Associations with Patellofemoral Pathology (166)
Authors: DeVries Clarabelle , Bomar James , Pennock Andrew 
Published: October 2021

Objectives: Patellar instability is a common condition of adolescents with an incidence of 29 to 43 per 100,000. Trochlear dysplasia has been found in up to 85% of those with recurrent patellar instability and has been found in association with ACL rupture. However, the prevalence of trochlear dysplasia in the general population has not yet been defined. The purpose was to define the prevalence of trochlear dysplasia as defined by ultrasound in a skeletally mature population and characterize associations of trochlear dysplasia with patellofemoral pathology. Methods: Skeletally mature adolescents and parents aged 50 and under presenting to orthopedics clinics were recruited from 2019 to 2020. Those with a history of intra-articular fracture, total knee arthroplasty, and syndromic ligamentous laxity or neuromuscular disease were excluded. Surveys were collected detailing any history of knee symptoms and surgery as well as an abbreviated Anterior Knee Pain Score (AKPS) with a score of 4 or greater being considered positive. Ultrasounds were obtained of bilateral knees and the osseous sulcus angle of the trochlea as well as the trochlear depth were measured (Figure 1). Basic descriptive statistics are reported. Results: One hundred and two patients (203 knees) were studied. The mean osseous sulcus angle was 144.1±6.8° and the mean trochlear depth was 5.5±1.4mm. The distribution of outcomes of interest can be found in Table 1. High grade trochlear dysplasia was defined as two standard deviations from the mean which was shown to be a sulcus angle ≥158˚ or a trochlear depth of ≤3mm. Prevalence of high grade trochlear dysplasia based on sulcus angle was 3.0% and 5.9% based on trochlear depth. In the presence of high grade trochlear dysplasia as defined by osseous sulcus angle, there was a 32 times increased risk of previous patellar instability (p=0.007) and 10 times increased risk of a positive AKPS (p=0.016). All those with high grade trochlear dysplasia as defined by osseous sulcus angle had a history of, or current, patellofemoral pain. Conclusions: The prevalence of trochlear dysplasia in the general population is approximately 6%. There are significant associations of trochlear dysplasia not only with patellar instability but also with patellofemoral pain. Use of ultrasound to diagnose trochlear dysplasia may prove to be a rapid and useful tool in guiding patient education and treatment decisions.
Outcomes following Medial Patellofemoral Ligament Reconstruction with Allograft (177)
Authors: Markus Danielle , Hurley Eoghan , Shontz Edward , Campbell Kirk , Jazrawi Laith , Strauss Eric 
Published: October 2021

Objectives: Medial patellofemoral ligament reconstruction (MPFLR) using allograft tissue has several potential benefits including the absence of donor site morbidity, ability to predict graft parameters, and decreased operative time. The purpose of this study was to evaluate the outcomes of patients following MPFLR with allograft. Our hypothesis was that there would be a low rate of recurrent instability, and excellent clinical outcomes reported. Methods: A retrospective review of athletes who underwent MPFL Reconstruction, with a minimum of 12-month follow-up was performed. Recurrent instability (including re-dislocation and subluxation), Visual Analogue Scale (VAS) score, Kujala score, satisfaction, and whether they would undergo the same surgery again, were evaluated. Results: Overall, follow up was attained for 131 patients with 141 knees (73.4%). The mean patient age of 25.0 years, 67.4% females, and mean time to follow-up was 46.8 months (12-111). At final follow up, the mean VAS score was 1.4 ± 2.0, the mean Kujala score was 84.8 ± 15.6, the mean satisfaction score was 84% ± 26.0, and 117 (83.0%) would undergo the same procedure again if required. There was 17 (12.0%) patients that had recurrent instability, with 2 being re-dislocations (1.4%). A further procedure was performed in 14 patients (9.9%). There were no intra-operative complications in our series. Conclusions: There was a low rate of recurrent instability following MPFLR with allograft, with excellent patient reported outcomes, and a low complication rate.
Return to Play (RTP) and Performance in the Women’s National Basketball Association (WNBA) Following Anterior Cruciate Ligament (ACL) Reconstruction (194)
Authors: Tramer Joseph , Khalil Lafi , Ziedas Alexander , Abbas Muhammad , Mehran Nima , Okoroha Kelechi 
Published: October 2021

Objectives: The incidence of ACL injuries in WNBA athletes has been on the rise, despite the high rates of ACL injury there is a paucity of recent research examining the effect of ACL reconstruction on RTP and performance in these athletes. This cohort study seeks to quantify the effect of ACL reconstruction on RTP and performance on WNBA athletes. Methods: All ACL tears sustained in the WNBA from 1997-2018 were identified. BMI, age and position at the time of injury were collected for each player. RTP rates were calculated and performance data was collected for each player before and after injury to determine changes in playing time and statistical performance. Players who successfully RTP after ACL reconstruction were compared to a group of healthy controls who were matched by age, years of experience, position, height, and BMI. Statistics at one year and three years’ post-injury were compared to assess acute and longitudinal changes in performance relative to pre-injury baseline. Results: A total of fifty-nine WNBA players sustained an isolated ACL tear during the study period. Forty-one (69.5%) were able to RTP. There was no difference in demographic characteristics between forty-one players and matched controls. Following RTP athletes played an average of 7.5±12.8 fewer games, 5.1±9.2 fewer minutes per game, and scored 3.7±5.0 less points per game in their first year compared to the year prior to injury. (Table1) When compared to matched controls, WNBA players returning from ACL reconstruction demonstrated a significant decline in games played, games started, minutes per game, rebounds, assists, and blocks per game in their first season after RTP. These differences resolved by year three post-surgery (Table 2). Conclusions: There is a high RTP rate following ACL reconstruction in WNBA athletes. Players may experience a decrease in playing time and performance initially when returning to play, however these variables were found to return to baseline over time.
Application of Machine Learning Algorithms in the Prediction of Prolonged Postoperative Opioid Use in Patients Undergoing Elective Shoulder Arthroscopy (215)
Authors: Lu Yining , Lavoie-Gagne Ophelie , Karhade Aditya , Forlenza Enrico , Schwab Joseph , Cole Brian , Verma Nikhil , Forsythe Brian 
Published: October 2021

Objectives: Recovery after shoulder arthroscopy can be impaired by sustained postoperative opioid use, yet there are few validated risk calculators for this outcome. The purpose of this study is to develop and validate a machine learning algorithm that can reliably and effectively predict sustained opioid use in patients following elective shoulder arthroscopy. Methods: A retrospective review of an institutional outcomes database was performed at a tertiary academic medical center to identify adult patients who underwent shoulder arthroscopy between January 1, 2014 and October 1, 2019. Extended postoperative opioid consumption was defined as opioid consumption at least 150 days following surgery. Five machine learning algorithms were developed to predict this outcome. Performance of the algorithms were assessed through discrimination, calibration, and decision curve analysis. Results: Overall, of the 1504 patients included, 132 (8.8%) demonstrated sustained postoperative opioid consumption. The factors determined for prediction of prolonged postoperative opioid prescriptions were preoperative opioid use, age, median percentage of population in patient zip code living at the federal poverty line, preoperative pain score, duration of symptoms, BMI. The random forest model achieved the best performance based on discrimination (AUC = 0.78), calibration, and decision curve analysis. This model was integrated into a web-based open-access application able to provide both predictions and explanations. Conclusions: If externally validated in independent populations, the algorithm developed presently could effectively guide preoperative screening in patients at high risk for extended postoperative opioid prescriptions. Early identification and interdisciplinary counseling in high-risk cases can optimize both resource allocation and surgical outcomes.
Update On Performance And Return To Sport After Biceps Tenodesis In Professional Baseball Players (226)
Authors: Erickson Brandon , Chalmers Peter , Dangelo John , Ma Kevin , Rowe Dana , Ciccotti Michael , Romeo Anthony 
Published: October 2021

Objectives: Determine the return to sport (RTS) rate and performance upon RTS in professional baseball players who underwent biceps tenodesis. Methods: All professional baseball pitchers who underwent biceps tenodesis between 2014 and 2017 were included. Players with concomitant rotator cuff repair were excluded. Demographic and performance data (preoperative and postoperative) were recorded for each player. Performance metrics were then compared between the biceps tenodesis and matched control (no history of biceps tenodeses) groups. Results: 14 players (average age 27±4 years; 12 pitchers, 2 position outfielders) were included. Most (79%) were open subpectoral tenodeses while one was an arthroscopic biceps transfer and one was arthroscopic suprapectoral. Fixation methods included cortical button (42%), interference screw (25%), suture anchor (25%) and drill holes (8%). Most players (79%) underwent concomitant procedures (43% underwent SLAP repair). Among the 14 players, 2 were unable to RTS, 5 RTS but to a lower level, and 7 RTS at the same or a higher level. Thus, overall, while 86% (12/14) were able to RTS, 50% (7/14) were able to return to the same or a better level and 50% were either unable to return or returned to a lower level. Among pitchers specifically, 100% (12/12) were able to return to play, but only 50% (6/12) were able to return to the same or a higher level. For those players who did return to play, it took 245±84 days, their performance was unchanged and did not differ from matched controls. Conclusions: While 86% of professional baseball players returned to sport following biceps tenodesis, only 50% returned at the same or higher level. No decline in performance was noted in players who successfully returned. Open subpectoral tenodesis is the most common tenodesis technique performed on professional baseball players.
All-Suture and Solid Medial Row Anchors Produce Similar Clinical Outcomes for Double Row Suture Bridge Rotator Cuff Repair (227)
Authors: Feldman John , Ochsner Mims , Fleisig Glenn , Tatum Rob , Grosz Lindsay , Hart Karen , Dugas Jeffrey , Emblom Benton , Cain E. Lyle 
Published: October 2021

Objectives: All-suture anchor use for rotator cuff repair is increasing. Potential benefits of these anchors include less bone loss from anchor hole drilling and decreased injury to the chondral surface with anchor pullout. Minimal evidence exists comparing clinical outcomes of all suture to solid medial row anchor fixation in double row suture bridge rotator cuff repair. The purpose of this study was to compare patient-reported outcomes for rotator cuff tears treated with all-suture medial row anchors to those treated with more traditional solid anchors. The null hypothesis was that there is no difference in outcomes between the all-suture and solid anchor rotator cuff repairs. Methods: Three sports medicine fellowship trained surgeons performed rotator cuff repairs using the double row suture bridge technique with minimum 3 years of follow up. Patients were separated into two groups based on whether or not they received all-suture or solid anchor fixation for the medial row of their repair. All lateral row fixation was performed with solid anchors. Primary outcomes were evaluated with telephone follow-up and included the American Shoulder and Elbow Surgery Score (ASES), Single Assessment Numeric Evaluation (SANE), and Visual Analog Scale (VAS). The Rehabilitation protocol was the same for all subjects in the study. Results: 3 sports medicine fellowship trained orthopaedic surgeons performed 153 rotator cuff repairs. 91 of these subjects had all-suture fixation of the medial row and 62 received solid anchor fixation. Follow up was 3.6 years ± 0.6 for the all-suture group and 3.7 years ± 0.6 in the solid anchor group (p= 0.28). ASES scores were 92 ± 16 in the all-suture group and 90 ± 17 in the solid group (p =0.35). SANE scores were 91 ± 13 in the all-suture and also 91 ± 13 in the solid anchor cohort (p = 0.97). VAS scores were 1.1 ± 2.0 in the all-suture and 0.7± 1.8 in the solid anchor group (p=0.17). There were no significant differences between groups with regards to re-operation rate or anchor configuration. Conclusions: All suture anchors used in medial row fixation for double row suture bridge rotator cuff repairs have similar clinical outcomes to rotator cuff tears treated in similar fashion with solid medial row anchors.
Significance of the Acromiohumeral Distance on Stress Radiography for Predicting Healing and Function after Arthroscopic Repair of Massive Rotator Cuff Tears (231)
Authors: Jeon Young Dae , Jeong Hyeon Jang , Oh Joo Han 
Published: October 2021

Objectives: Decreased acromiohumeral distance (AHD) is commonly detected in massive rotator cuff tears (mRCT). Most studies evaluating fixed humeral elevation have used preoperative or postoperative standardized radiography, and not stress radiography. We aimed to evaluate the role of preoperative AHD using stress radiography for healing and function after arthroscopic repair of mRCT. Methods: We analyzed the data of 113 patients who underwent arthroscopic repair of mRCT, whose postoperative cuff integrity was evaluated using magnetic resonance imaging at 1 year and whose functions were evaluated at a mean of 34.9 ± 17.8 months. Forty-seven patients showed healing failure. Propensity score matching (1-to-1) was performed between the healed and healing failure groups. 38 patients in each group were matched in the final analysis. We defined AHD and AHD_stress as the shortest distances from the inferior acromion to the superior humerus on standard anteroposterior and stress radiography (5.4 kg weight applied inferiorly in a neutral position), respectively. AHD difference (AHD_diff) was defined as the difference between AHD and AHD_stress. Results: There was no difference in the mean preoperative AHD between the healed (7.5 ± 2.0) and healing failure groups (6.9 ± 2.2, p = 0.234). AHD_diff was significantly higher in the healed (4.4 ± 2.1mm) than in the healing failure group (3.0 ± 2.0 mm, p = 0.002: cutoff, 3.2 mm). Patients with AHD_diff ≥3.2 mm showed lower healing failure (28.9% vs 71.1%, p < 0.001) and higher functional scores than those with AHD_diff <3.2 mm. AHD_diff was higher in the American Shoulder and Elbow Surgeons (ASES) ≥80 (4.9 ± 1.9 mm) than in the ASES <80 group (3.1 ± 2.1 mm, p = 0.024). Only postoperative AHD was related to postoperative functions (cutoff, 4.8 mm, p = 0.009) in the healing failure group. Conclusions: The AHD_diff measured using preoperative stress radiography can be another predictor of rotator cuff healing and function after arthroscopic repair of mRCT and would be helpful to determine appropriate treatment strategies.
Long Term Outcomes of Anterior Shoulder Instability in Throwers and Overhead Athletes at a Mean Follow-up of 15 years (240)
Authors: Shirley Matthew , Nauert Richard , Wilbur Ryan , LaPrade Matthew , Bernard Christopher , Song Bryant , Leland Devin , Krych Aaron , Camp Christopher 
Published: October 2021

Objectives: There is a paucity of literature regarding outcomes of anterior shoulder instability (ASI) in throwers and overhead athletes (OHA). The purpose of this study was to report the pathology, treatment strategies, and outcomes of ASI in throwers and overhead athletes utilizing an established US geographic population-based cohort. Methods: An established geographic database of more than 500,000 patients was used to identify athletes <40 years of age with ASI between 1994 and 2016. Medical records were reviewed to obtain demographics, type of sport, surgical details, and clinical outcomes. Patients were contacted after final clinical follow-up for patient reported outcomes (PRO). The Western Ontario Shoulder Instability (WOSI) score, return to sport at previous level of performance (RPP), rate of return to play (RTP) and time to RTP were recorded. Statistical analysis was performed comparing throwers to non-throwers and OHA to non-overhead athletes (NOHA). Results: The study population consisted of 171 patients, 114 NOHA and 57 OHA. Of the OHA, 40 were throwers. The mean follow-up was 14.7 ± 5.6 years for PRO’s and 11.7 ± 7.3 years for last clinical evaluation. No difference in overall instability events was seen in either group. Throwers were more likely to present with subluxations while non-throwers were more likely to present with frank dislocations. NOHA and non-throwers were more likely than OHA and throwers to have a history of trauma related to ASI, respectively ( P = <.001, P = .002). Throwers were more likely to undergo an open surgical procedure (45%) than non-throwers (15%) ( P = .038). The rate of recurrent instability between groups was similar. Throwers returned to sport at a lower rate than non-throwers, however this did not reach significance (64% vs 83%, P = .100). Throwers and OHA reported similar WOSI scores, RPP and time to RTP grouped by surgical or conservative management compared to non-throwers and NOHA, respectively. Conclusions: In a US cohort of patients, throwers and OHA had a similar number of instability events compared to non-throwers and NOHA, respectively. Non-throwers and NOHA were more likely to present with frank dislocation which is supported by the significantly higher rates of trauma in both groups. Notably, the WOSI score, RPP, rate of RTP and time to RTP showed no difference between throwers and OHA when compared to their non-throwing and NOHA counterparts.
Primary versus revision arthroscopic bridging reconstruction using dermal allograft: a clinical and radiographic analysis (243)
Authors: Wong Ivan , Sparavalo Sara , Ma Jie , Alkhatib Nedal 
Published: October 2021

Objectives: Large or massive rotator cuff tears make up between 10-40% of all rotator cuff tears, yet there is no agreement on the best treatment. Previous studies have shown that acellular human dermal allograft (AHDA) can be used for bridging reconstruction with positive patient outcomes. The use of this surgical technique has not been extensively studied in the primary or revision surgical setting. The main objective of this study was to compare the clinical and radiographic outcomes of patients who received primary or revision arthroscopic bridging reconstruction. Methods: This study is a retrospective review of a sequential series of patients who underwent arthroscopic bridging reconstruction (ABR) using AHDA by the primary author (IW). A total of 130 patients underwent ABR between 2010 and 2018. The inclusion criteria were patients with completed Western Ontario Rotator Cuff (WORC) questionnaire, Disabilities of the Arm, Shoulder, and Hand (DASH) score, or both pre-operatively and at multiple post-operative timepoints. Patients with missing WORC scores were excluded from the study. Eighty-three patients were included following chart review. Patients with available post-operative MRIs were also used for radiological assessment by an independent MSK-trained radiologist. Post-operative MRIs were reviewed to assess for graft integrity and changes to rotator cuff muscle atrophy (using the Warner classification) and fatty degeneration (using the Goutallier classification). Results: There were 46 patients who received primary ABR and 37 who received revision ABR. Forty-eight patients had a post-operative MRI available for review (Primary: 25; Revision: 23). The demographics are summarized in Table 1. Both groups showed a significant improvement in WORC score post-operatively (p<0.001). Primary ABR resulted in higher post-operative WORC scores as compared to revision ABR (p=0.015; Figure 1). The incidence of complete re-tears in the primary group was 8% and 17.4% in the revision group. More than 35% of patients in the primary group showed improvement in fatty infiltration of the infraspinatus and supraspinatus muscles. There was a higher progression in muscle atrophy in the revision group as compared to the primary group (74% and 30%, respectively). Conclusions: Arthroscopic primary arthroscopic bridging reconstruction for large/massive rotator cuff tears using acellular human dermal allograft had better improvement in their WORC scores compared to revision group at the final follow-up. Although the revision group had improved at the two-year follow-up, these changes in WORC score were not sustained at the final follow-up while the improvements were maintained for the primary group. The primary group had a smaller re-tear rate, better fatty infiltration and muscle atrophy as compared to the revision group. This suggests that primary bridging reconstruction provides better outcomes than a revision surgery.
In the Asia-Pacific region, the COI DNA test revealed the divergence of the bivalve mollusc Mactra chinensis into three species; can these species be distinguished using shell coloration and sperm structure?
Authors: Reunov Arkadiy , Lutaenko Konstantin , Vekhova Evgenia , Zhang Junlong , Zakharov Evgeny , Sharina Svetlana , Alexandrova Yana , Reunova Yulia , Akhmadieva Anna , Adrianov Andrey 
Published: October 2021

AbstractAccording to COI DNA barcoding testing, the marine bivalve mollusc Mactra chinensis, which is native to the Asia-Pacific region, diverged into three species. These species were preliminary characterized as M. chinensis COI clade I, M. chinensis COI clade II and M. chinensis COI clade III. To find out whether it is possible to morphologically distinguish samples representing genetic clades, we examined the color of the shells and the structure of the spermatozoa. It was found that the number of detected coloration types exceeds the number of detected species. In addition, it was shown that individuals belonging to the same genetic clade can have shells of different colors. Consequently, it is impossible to choose one type of shell coloration as a species-specific trait. For sperm, the sperm morphological patterns found in each of the three species are consistent with the M. chinensis sperm model described in previous reports. However, the single sperm variant is also not applicable to discriminate between species derived from M. chinensis, since heterogeneous variants of spermatozoa differing in the length of the acrosomal rod were found. We hypothesized that genetic divergence of species could cause a shift towards predominance of one of the sperm variants, and that species-specific sperm morphs could be quantitatively dominant in molluscs belonging to different clades. However, the dominant sperm morphs were the same in COI clade I and COI clade III. Thus, dominant sperm morphs are useless as species-specific traits. However, shell color and sperm parameters are specific to different geographic regions, and it seems that unique environmental factors can determine shell color and sperm morphology. As a result, both shells and spermatozoa can be used to distinguish the geographical forms of M. chinensis, regardless of the belonging of the forms to a particular genetic clade. Here we propose the introduction of geographic identifiers, in which the shell color and parameters of sperm sets are used as morphological criteria to determine the geographical origin of mollusc specimens belonging to the M. chinensis species complex.