bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute respiratory distress syndrome (ARDS) after pressurized intraperitoneal aerosol chemotherapy with oxaliplatin: a case report
Authors: Thibaudeau Emilie , Brianchon Corinne , Raoul Jean-Luc , Dumont Frédéric 
Published: October 2021

Abstract
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new drug delivery method for intraabdominal cavity chemotherapy. It combines the benefits of a minimally invasive approach (low morbidity and easy to repeat) with the pharmacokinetic advantages of intraperitoneal administration and tolerance seems excellent. We would like to report one case of a serious adverse event, acute respiratory distress syndrome, which is likely related to oxaliplatin administration; all signs disappeared within a few days.
Comparison of nonlinear solvers within continuation method for steady-state variably saturated groundwater flow modelling
Authors: Anuprienko Denis 
Published: October 2021

Abstract
Nonlinearity continuation method, applied to boundary value problems for steady-state Richards equation, gradually approaches the solution through a series of intermediate problems. Originally, the Newton method with simple line search algorithm was used to solve the intermediate problems. In the present paper, other solvers such as Picard and mixed Picard–Newton methods are considered, combined with slightly modified line search approach. Numerical experiments are performed with advanced finite volume discretizations for model and real-life problems.
“Hope it’s not just the honeymoon phase”: online discursive portrayals of migrant domestic helpers
Authors: Ho Janet 
Published: October 2021

AbstractThis paper examines online discursive representations of migrant domestic helpers (MDHs) by Hong Kong employers. Unlike existing research, which concentrates on the experiences of MDHs from their own perspectives, this study focuses on positive narrations about MDHs by their employers. Using critical discourse analysis, this study identified the discursive strategies deployed to portray MDHs in more than 2,000 Facebook posts. The findings reveal that, although the interlocutors attempted to commend the MDHs in their employ, they also emphasised their own superiority by portraying themselves as gastronomic experts, good educators, and benefactors, thus developing an ideological paradox. Another dimension of ideological ambivalence concerned the discursive conflict between their high expectations from the MDHs and their underlying belief that domestic work neither requires skills nor deserves high pay. Taken together, these factors are responsible for the entrenchment of the inferior image of MDHs in Hong Kong society, despite the persistent endeavours of activist groups to spread awareness of their exploitation.
Toxic effects of formaldehyde and the protective effect of docosahexaenoic acid in Drosophila
Authors: Hua Yanli , Ma Chao , Huang Shuyi , Wang Ruomeng , Chen Jian , Guo Qing , Zhou Jiaojiao , Zhu Hemin , Li Wenjie 
Published: October 2021

Abstract
Formaldehyde (FA) is a commercially important chemical applied in industry and scientific research. However, FA has a distinct impact on learning and memory. Although the mechanisms of FA toxicity have been well studied, additional research is required to establish the mechanisms of neuroprotection in cases of FA exposure. Docosahexaenoic acid (DHA) is a polyunsaturated fatty acid with a variety of health benefits, including the enhancement of learning and memory. In this study, we investigated the neuroprotective effects of DHA in Drosophila melanogaster that had ingested FA. Our data suggested that DHA enhanced reproductive processes, leading to an increase in the number of eggs, larvae, and adults. Surprisingly, we found that DHA had a mild protective effect against FA-induced impairments in learning and memory.
Hermann Kantorowicz’ Vortrag auf dem ersten Soziologentag 1910
Authors: Haferkamp Hans-Peter 
Published: October 2021

ZusammenfassungAls eine Art Entsandter der Freirechtsbewegung und Vertreter der Jurisprudenz sprach Hermann Kantorowicz auf Einladung von Max Weber vor dem Ersten Soziologentag 1910 in Frankfurt a. M. Sein Vortrag war in mehreren Perspektiven bedeutsam. Zunächst musste Kantorowicz seine Thesen aus dem berühmten „Kampf um die Rechtswissenschaft“ von 1906 präzisieren, um zu einer klaren Bestimmung des Verhältnisses zwischen Rechtswissenschaft und Soziologie zu gelangen. Dies führte zu klaren Abgrenzungen zu anderen „Freirechtlern“, insbesondere zu Eugen Ehrlich und den in Frankfurt anwesenden Ernst Fuchs und Hans Wüstendörfer. Viel deutlicher arbeitete er auch die Grundlagen einer Methodologie der Rechtswissenschaft heraus, wofür er sich erstmals zu Heinrich Rickert bekannte. Schließlich wurde schon in Frankfurt deutlich, dass sich die Annäherung an die Empirie für Kantorowicz als Durchgangsstadium erweisen würde, da bereits hier die drängende Problematik einer Wertphilosophie durchschimmerte, die ihn in späteren Jahren immer stärker interessieren sollte. Obwohl der Vortrag bei Max Weber große Zustimmung fand, löste die Diskussion große Kontroversen aus, die mit zur baldigen Krise der Deutschen Gesellschaft für Soziologie beitrugen.
Copper(I) iodide-based organic–inorganic hybrid compounds as phosphor materials
Authors: Hei Xiuze , Fang Yang , Teat Simon J. , Farrington Colin , Bonite Megan , Li Jing 
Published: October 2021

Abstract
Two photoluminescent copper(I) iodide inorganic-organic hybrid materials have been synthesized and structurally characterized as 1D-Cu2I2(bpoe)2 (1) and 1D-Cu2I2(bbtpe-m)2 (2) (bpoe = 1,2-bis(pyridin-3-yloxy)ethane, bbtpe-m = 1,1′-(3-methylpentane-1,5-diyl)bis(1H-benzo[1,2,3]triazole). Both are chain-like structures composed of Cu2I2 rhomboid dimers connected by bidentate ligands. Their emission colors range from cyan to yellow with relatively high internal quantum yields in the solid state. The tunable band gap and emission color is achieved by varying the LUMO energies of the ligands. The structures are robust and remain stable up to T = 260 °C, and coupled with their efficient and adjustable luminescence, facile synthesis, and non-toxic nature, these compounds demonstrate potential as rare earth element (REE)-free phosphors.
Adolescent Dopamine Neurons Represent Reward Differently during Action and State Guided Learning
Authors: McCane Aqilah M. , Wegener Meredyth A. , Faraji Mojdeh , Rivera-Garcia Maria T. , Wallin-Miller Kathryn G. , Costa Vincent D. , Moghaddam Bita 
Published: October 2021

Neuronal underpinning of learning cause-and-effect associations in the adolescent brain remains poorly understood. Two fundamental forms of associative learning are Pavlovian (classical) conditioning, where a stimulus is followed by an outcome, and operant (instrumental) conditioning, where outcome is contingent on action execution. Both forms of learning, when associated with a rewarding outcome, rely on midbrain dopamine neurons in the ventral tegmental area (VTA) and substantia nigra (SN). We find that, in adolescent male rats, reward-guided associative learning is encoded differently by midbrain dopamine neurons in each conditioning paradigm. Whereas simultaneously recorded VTA and SN adult neurons have a similar phasic response to reward delivery during both forms of conditioning, adolescent neurons display a muted reward response during operant but a profoundly larger reward response during Pavlovian conditioning. These results suggest that adolescent neurons assign a different value to reward when it is not gated by action. The learning rate of adolescents and adults during both forms of conditioning was similar, supporting the notion that differences in reward response in each paradigm may be because of differences in motivation and independent of state versus action value learning. Static characteristics of dopamine neurons, such as dopamine cell number and size, were similar in the VTA and SN of both ages, but there were age-related differences in stimulated dopamine release and correlated spike activity, suggesting that differences in reward responsiveness by adolescent dopamine neurons are not because of differences in intrinsic properties of these neurons but engagement of different dopaminergic networks.SIGNIFICANCE STATEMENTReckless behavior and impulsive decision-making by adolescents suggest that motivated behavioral states are encoded differently by the adolescent brain. Motivated behavior, which is dependent on the function of the dopamine system, follows learning of cause-and-effect associations in the environment. We find that dopamine neurons in adolescents encode reward differently depending on the cause-and-effect relationship of the means to receive that reward. Compared with adults, reward contingent on action led to a muted response, whereas reward that followed a cue but was not gated by action produced an augmented phasic response. These data demonstrate an age-related difference in dopamine neuron response to reward that is not uniform and is guided by processes that differentiate between state and action values.
CDKL5 kinase controls transcription‐coupled responses to DNA damage
Authors: Khanam Taran , Muñoz Ivan , Weiland Florian , Carroll Thomas , Morgan Michael , Borsos Barbara N , Pantazi Vasiliki , Slean Meghan , Novak Miroslav , Toth Rachel , Appleton Paul , Pankotai Tibor , Zhou Houjiang , Rouse John 
Published: October 2021

AbstractMutations in the gene encoding the CDKL5 kinase are among the most common genetic causes of childhood epilepsy and can also give rise to the severe neurodevelopmental condition CDD (CDKL5 deficiency disorder). Despite its importance for human health, the phosphorylation targets and cellular roles of CDKL5 are poorly understood, especially in the cell nucleus. Here, we report that CDKL5 is recruited to sites of DNA damage in actively transcribed regions of the nucleus. A quantitative phosphoproteomic screen for nuclear CDKL5 substrates reveals a network of transcriptional regulators including Elongin A (ELOA), phosphorylated on a specific CDKL5 consensus motif. Recruitment of CDKL5 and ELOA to damaged DNA, and subsequent phosphorylation of ELOA, requires both active transcription and the synthesis of poly(ADP‐ribose) (PAR), to which CDKL5 can bind. Critically, CDKL5 kinase activity is essential for the transcriptional silencing of genes induced by DNA double‐strand breaks. Thus, CDKL5 is a DNA damage‐sensing, PAR‐controlled transcriptional modulator, a finding with implications for understanding the molecular basis of CDKL5‐related diseases.
Meaning in Life During Covid-19 Pandemic and Social Interaction Anxiety : The Relevant Facets
Authors: Gangopadhyay Mayurakshee 
Published: October 2021

The meaning of life is steadily altering in the Covid-19 pandemic scenario. Since birth, life and living have been the major preoccupation of every human being. However, there remains a constant possibility of death owing to a pandemic breakout. The ways of social interaction and associated psychosocial issues are also of great importance in the present condition. This study thus aimed at finding out the interrelationship between meaning in life and social interaction anxiety among young adults. The study used a quantitative research method with the help of the Meaning in Life Questionnaire by Steger and Social Interaction Anxiety Scale by Mattick and Clarke on 100 samples of both the Gender, i.e., male and female aged between 21 to 25 years. The findings showed that meaning in life has a significant negative correlation with social interaction anxiety. And social interaction anxiety is found out to be negatively predicted by meaning in life.
PRELIMINARY DEVELOPMENT OF RADIONUCLIDES RELEASE OF INDIVIDUAL DOSE CODE PROGRAM FOR RADIATION MONITORING PURPOSES
Authors: Pane Jupiter Sitorus , Udiyani Pande Made , Setiawan Muhammad Budi , Widodo Surip , Susila I Putu 
Published: October 2021

Environmental radiation monitoring is one of the important efforts in protecting society and the environment from radiation hazards, both natural and artificial. The presence of three nuclear research reactors and plans to build a nuclear power plant reactor prompted Indonesia to prepare a radiation monitoring system for safety and security (SPRKK). The goal of the study is to provide an appropriate method for developing radiation monitoring system to support the development of nuclear power plant in the near future. For this preliminary study, the author developed a code program using Gaussian distribution model approach for predicting radionuclide release and individual dose acceptancy by human being within 16 wind directions sectors and up to 50 km distance. The model includes estimation of source term from the nuclear installation, release of radionuclides source into air following Gaussian diffusion model, some of the release deposit to the land and entering human being through inhalation, direct external exposure, and resuspension, and predicted its accepted individual dose. This model has been widely used in various code program such as SimPact and PC-Cosyma. For this study, the model will be validated using SimPact code program. The model has been successfully developed with less than 5% deviation. Further study will be done by evaluating the model with real measuring data from research reactor installation and prepare for interfacing with real time radiation data acquisition and monitoring as part of radiation monitoring system during normal and accident condition.
Sedimentology and Ichnology of Paleozoic Estuarine and Shoreface Reservoirs, Morrow Sandstone, Lower Pennsylvanian of Southwest Kansas, USA
Authors: Buatois Luis A. , Mangano Gabriela M. , Carr Timothy R. 
Published: October 2021

Integration of facies and trace-fossil evidence tests and refines depositional models constructed solely on the basis of physical sedimentology. In recent years, the petroleum industry has increasingly used trace-fossil analysis of cores as an aid in reservoir characterization. In particular, ichnologic data have been instrumental in the recognition of estuarine deposits and their distinction from open-marine facies (e.g., MacEachern and Pemberton, 1994). Previous ichnologic analyses of cores, however, have concentrated on post-Paleozoic reservoirs (e.g., Bockelie, 1991; Pemberton, 1992; Taylor and Gawthorpe, 1993; Howell et al., 1996; Martin and Pollard, 1996; MacEachern and Pemberton, 1997). The present study represents one of the first attempts to apply trace-fossil analysis to cores from Paleozoic reservoirs.
The Lower Pennsylvanian Morrow Sandstone contains oil and gas reservoirs in a wide variety of shallow and marginal-marine depositional environments. Delta-front, shoreface, and estuarine valley-fill reservoir sandstones are encased in offshore and estuarine mudstones (Sonnenberg, 1985; Krystinik and Blakeney, 1990; Sonnenberg et al., 1990; Wheeler et al., 1990). An integrated stratigraphic, sedimentologic, and ichnologic study provides a more accurate characterization of reservoir facies and geometry. This study allows distinction between marine-shoreface and estuarine valley-fill sandstones from four cores of the lower Morrow in southwestern Kansas. Core analysis subsequently was integrated with well-log information. Previous studies have emphasized the presence of estuarine valley-fills in the upper Morrow (Wheeler et al., 1990). Our integrated approach extends the estuarine valley interpretation into the lower Morrow. Within the midcontinent, trace fossils are useful in distinguishing different facies in estuarine incised valleys and marine shorefaces. Detailed study of biogenic structures provides high-resolution information to solve problems in facies, stratigraphic, and reservoir modeling. In some cases, they represent the only evidence available to develop a reasonable picture of depositional conditions and to estimate reservoir heterogeneity. The present study provides a detailed analysis of the sedimentary facies, documents the associated trace fossils, and illustrates how trace fossils are used to refine environmental interpretations of the lower Morrow sandstone reservoirs.
Paleoecology of the Permian (Wolfcampian) Phylloid Alga Calcipatera from an In Situ Occurrence in Kansas, U.S.A.
Authors: Sawin Robert S. , West Ronald R. 
Published: October 2021

In situ occurrences of the calcareous marine phylloid alga Calcipatera cottonwoodensis in the Permian Cottonwood Limestone Member (Beattie Limestone) occur in Greenwood County, Kansas, in association with platy algal packstones, which are the phylloid algal facies most commonly described in the literature. The in situ algal facies occurs in the upper 0.45 m of an exposure where it is overlain and underlain by algal packstones composed of transported and broken fragments of Calcipatera cottonwoodensis.
Calcipatera cottonwoodensis colonized coarse carbonate sands or carbonate mud substrates. During growth, carbonate mud accumulated in the cup-shaped thalli, and death followed when the rate of sedimentation exceeded the rate of algal growth. The three lithologies--substrate, cup-filling, and smothering--are easily recognized on polished surfaces.
Other members of the Calcipatera cottonwoodensis benthic community are Shamovella, encrusting and boring algae, foraminiferids, fenestrate and ramose bryozoans, brachiopods, bivalves, gastropods, trilobites, ostracodes, and echinoids. This occurrence and biotic association compares well with those described by Toomey (1976) and Wahlman (1988, 2002) from the Permian (Wolfcampian) of West Texas.
Reconstructing Late Cenozoic Stream Gradients from High-Level Chert Gravels in Central Eastern Kansas
Authors: Harbaugh John W. , Merriam Daniel F. , Howard Hugh H. 
Published: October 2021

Interpreting the evolution of Kansas' landscape east of the Flint Hills provides major challenges. In the Neogene (late Tertiary) and perhaps part of the Pleistocene, streams transported a variety of sedimentary materials, including chert gravels derived from the Flint Hills. Gentle intermittent uplift stimulated the stream system to cut down, locally removing and reworking the gravels to create stream-terrace deposits that consist mostly of chert pebbles, which now lie well above the floodplains of modern streams. By correlating the elevations of these gravels, the gradients of the trunk streams that deposited them can be reconstructed. Interestingly, these ancient streams flowed southeast at a little more than a foot per mile (0.2 m/km), roughly the same as the gradient of the trunk streams in the region today.
The evolving landscape in eastern Kansas also has been strongly influenced by an extensive network of fractures that is widespread in the midcontinent region and may be worldwide in extent. In northeastern Kansas, glaciation during the Pleistocene disrupted the southeasterly drainage and established the present location of the Kansas River. South of the Kansas River and its immediate tributaries, however, the general southeasterly drainage has been preserved.
We have made use of the wealth of topographic-elevation data now available in digital form known as DEMs or digital elevation models. Coupled with GIS procedures, the DEMs helped link the mapped distribution of chert gravels with hypothetical fitted surfaces that represent ancient stream gradients. Furthermore, DEM data placed in shaded-relief map form emphasize the influence of fractures in evolution of the drainage system.
Palynological Correlation of Atokan and Lower Desmoinesian (Pennsylvanian) Strata Between the Illinois Basin and the Forest City Basin in Eastern Kansas
Authors: Peppers Russel A. , Brady Lawrence L. 
Published: October 2021

Palynological correlation is made between Atokan and lower Desmoinesian strata in the Illinois basin and the Forest City basin in eastern Kansas. Spore data from previous studies of coals in the Illinois basin and other coal basins are compared with data from spore assemblages in coal and carbonaceous shale bands in a core drilled in Leavenworth County, Kansas. Correlations are based on first and/or last occurrences of 31 species common to the Illinois basin and eastern Kansas and on significant increases or decreases in abundance of several of those taxa. The oldest coal, which is 26 ft (8 m) above the top of the Mississippian, is early Atokan (early Westphalian B) in age and is approximately equivalent to the Bell coal bed in the Illinois basin. The Riverton coal bed at the top of the studied interval in Kansas is early Desmoinesian (early Westphalian D) and correlates with about the Lewisport coal bed in the Illinois basin. Three coal beds near the base of the Pennsylvanian in three cores drilled in Cherokee County, Kansas, which were also studied, range in age from late Atokan to early Desmoinesian.
As in other coal basins, Lycospora, borne by lycopod trees, greatly dominates the lower and middle Atokan spore assemblages in coals and shale, but spores from ferns, especially tree ferns, significantly increase in abundance in the upper Atokan and lower Desmoinesian. The pattern of change of dominance among Lycospora pellucida, L. granulata, and L. micropapillata in middle Atokan (Westphalian B-C transition) that has been demonstrated earlier in the Illinois basin and eastern Kentucky and Tennessee, also occurs in eastern Kansas. At least 10 species of spores, which appeared in the middle Atokan in other parts of the equatorial coal belt, also appeared at this time in eastern Kansas. Most of these species have their affinities with the ferns, which were adapted to drier habitats than lycopods. Thus, the climate may have become a little drier in the equatorial coal belt during middle Atokan.
Preliminary Identification of Ground-Water Nitrate Sources Using Nitrogen and Carbon Stable Isotopes, Kansas
Authors: Townsend M. A. , Macko S. A. 
Published: October 2021

Increasing nitrate-N in ground water is a problem in many areas with limited ground-water supplies, such as west-central Kansas. However, potential sources of nitrate-N are not known. Nitrate-N concentrations in ground water in the Hays study area in Ellis County, west-central Kansas, range from 0.9 to 26 mg/L. The δ15N signatures of the ground waters are more enriched (+16.8 to +28.7‰) than those of the soils (+8.4 to +13.7‰), strongly suggesting that nitrogen sources are not from mineralized and labile nitrogen present in the unsaturated zone. In this study, nitrate-N values greater than the U.S. EPA drinking water limit of 10 mg/L occur with δ15N values of greater than +10‰. This relationship between high nitrate-N concentrations and enriched δ15N values (greater than +10‰) in ground water has been observed in other studies in Kansas and is usually related to a human- and/or animal-waste source.
Soil cores collected near municipal wells had mean total nitrogen values of 1.2-15 mg/kg. Increased δ15N with depth in several of the cores suggests that microbial mineralization, denitrification, or volatilization processes caused the enriched δ15N signatures. Decreasing total nitrogen and nitrate-N values with depth also help support the idea of microbial processes.
Stable carbon isotopes provide supporting evidence that soils are not a major contributor to the observed nitrate-N concentration in the ground water. δ13C values of the dissolved organic carbon (DOC) in soils generally were more enriched (-11.6 to -18.8‰) while corresponding ground-water δ13C values were more depleted (-19.9 to -22.2‰), suggesting that the source of the DOC in ground water is not from the soils.