bluuebunny/crossref_metadata_2025_split huggingface dataset:
NHẬN XÉT KẾT QUẢ ĐIỀU TRỊ NGỘ ĐỘC CHÌ CẤP Ở TRẺ EM DO DÙNG “THUỐC CAM”
Authors: Thị Hồng Đinh , Ngọc Duy Lê , Thị Mai Hồng Trương 
Published: December 2021

Mục tiêu: Nghiên cứu một số đặc điểm lâm sàng, cận lâm sàng và đánh giá hiệu quả điều trị ngộ độc chì ở trẻ em do sử dụng “thuốc cam”. Đối tượng và phương pháp nghiên cứu: mô tả, cắt ngang trên 89 trẻ, tại Bệnh viện Nhi Trung ương, trong thời gian từ 6/2012 đến 6/2021. Kết quả: 60,7% trẻ dưới 1 tuổi; 47,2% trẻ được bôi vì tưa miệng. Triệu chứng lâm sàng: thay đổi tri giác (40,4%), co giật (48,3%), da xanh (82%), nôn (61,8%), tiêu chảy (29,2%). Cận lâm sàng: 80% xquang có tăng cản quang đầu xương dài; giãn não thất 9,4%; xuất hiện sóng động kinh trên điện não đồ 19,4%. Dịch não tủy biến đổi với protein tăng cao (1,64 ± 1,36 g/l) trong khi tế bào bình thường hoặc tăng nhẹ (9,8 ± 24,89 bạch cầu). Nồng độ chì máu trung bình lúc nhập viện 108,39 ± 55,8 µg/dl. Sau 30 ngày điều trị nồng độ chì máu giảm 49,7%, sau 1 năm giảm 71,3% và chì niệu đã tăng thải nhanh tại T5 và T30 với giá trị cao nhất là 5,664 mg/l. Tỷ lệ tử vong là 6/89 trẻ (6,7%). Kết luận: Biểu hiện lâm sàng của ngộ độc chì thường gặp là co giật, thay đổi tri giác và thiếu máu. Biến đổi dịch não tủy theo kiểu protein tăng, tế bào bình thường. Nồng độ chì máu giảm dần và chì niệu tăng dần trong quá trình điều trị. Tỷ lệ tử vong là 6,7%
Avaliação dos estágios de comportamento alimentar de indivíduos com obesidade em ambulatório da atenção especializada
Authors: Luz Cássia Regina , Farias Fernanda Bezerra Queiroz , Neves Josué Guedes , Macedo Ana Beatriz , Cabrini Daniele 
Published: December 2021

Introdução: O questionário de avaliação do Estágio de Prontidão para Mudança de Comportamento baseado no Modelo Transteórico avalia comportamentos relacionados à alimentação e prática de atividade física. Dessa forma é possível investigar o efeito dos tratamentos na mudança do comportamento de indivíduos com obesidade e propor intervenções necessárias. Objetivo: Analisar os efeitos de uma intervenção educativa em saúde para o tratamento da obesidade sobre o comportamento alimentar e a atividade física de indivíduos com obesidade. Material e Método: A intervenção constituiu-se de cinco oficinas educativas em grupo. Analisou-se 27 questionários aplicados na primeira oficina e na última oficina. Esse questionário avalia os cinco estágios de comportamento (pré-contemplação, contemplação, preparação, ação, manutenção) em quatro domínios (porções de alimentos, gorduras, frutas e verduras e atividade física). Resultados: A avaliação global, realizada por meio da frequência de respostas, demonstra que, na primeira oficina, 40,7% apresentavam-se em estágio de pré-ação (pré-contemplação, contemplação ou preparação). Na última oficina, apenas 19,6% permaneceram nesse estágio. Portanto, 81,4% encontravam-se em estágio de ação (ação ou manutenção) ao final das oficinas. Os domínios com melhor desempenho foram porções de alimentos e atividade física com uma redução dos indivíduos em pré-ação de aproximadamente 27%. Conclusão: A intervenção desenvolvida demonstrou-se eficaz na evolução dos estágios de prontidão para a mudança de comportamento alimentar e de atividade física. A evolução foi favorável porque a maioria dos indivíduos com obesidade participantes das oficinas educativas estavam, ao final, mais motivados para mudar seu comportamento.
PROFIL PERESEPAN OBAT ANTIHIPERTENSI PERIODE JANUARI 2019 SAMPAI DENGAN DESEMBER 2019 DI PUSKESMAS TANGKAHAN DURIAN KECAMATAN BERANDAN BARAT KABUPATEN LANGKAT
Authors: Sylvia Br. Ginting Ovalina , Taroreh Nahdiah 
Published: December 2021

Hipertensi merupakan suatu keadaan dimana terjadi peningkatan tekanan darah di atas ambang batas normal. Hipertensi perlu mendapat penanganan, salah satunya adalah upaya penanganan antihipertensi dengan terapi pemberian farmakologis antihipertensi. Penelitian ini bertujuan untuk mengetahui Kualitas Produk Obat Generik Berlogo (OGB) PT. Phapros Tbk Medan di Wilayah Medan Timur dan untuk mengetahui Profil Peresepan Obat Antihipertensi Periode Januari 2019 sampai dengan Desember 2019 di Puskesmas Tangkahan Durian Kecamatan Berandan Barat Kabupaten Langkat. Penelitian ini merupakan penelitian deskriptif yang pengumpulan data secara retrospektif. Penelitian ini telah dilaksanakan dengan mengambil data resep dari Januari 2019 sampai Desember 2019. Populasi dalam penelitian ini adalah seluruh resep-resep yang ada di Puskesmas Tangkahan Durian Periode Bulan Januari sampai dengan Desember 2019 sebanyak 583. Pengambilan sampel menggunakan Total sampling sehingga besar sampel adalah sebanyak 583 orang. Hasil Penelitian didapat bahwa Obat antihipertensi yang tersedia di Puskesmas Tangkahan Durian adalah Amlodipine 10 mg, Captopril 25 mg dan Nifedipine 10 mg, Presentase Penggunaan Obat Antihipertensi di Puskesmas Tangkahan Durian Periode Bulan Januari 2019 sampai dengan Bulan Desember 2019 yang paling sering diresepkan adalah Amlodipine 10 mg. Saran dalam penelitian ini diharapkan dengan adanya penelitian ini Puskesmas Tangkahan Durian terus berkontribusi memberikan pengobatan kepada masyarakat khususnya penyakit hipertensi untuk mencegah terjadinya komplikasi penyakit.
Kata kunci: Peresepan Obat Antihipertensi
RASIONALITAS PENGGUNAAN OBAT TUBERKULOSIS PARU DI PUSKESMAS PANGKALAN SUSU KABUPATEN LANGKAT SUMATERA UTARA
Authors: Zulfikri Zulfikri , Ainun Nur 
Published: December 2021

Tuberkulosis adalah penyakit menular yang disebabkan oleh Mycobacterium Tuberculosis. Penyakit TB masih menjadi permasalahan utama dalan bidang kesehatan terutama di Indonesia. Keberhasilan pengobatan TB sangatlah penting untuk mengurangi penularan penyakit dan kematian pasien TB. Salah satu faktor yang mempengaruhi keberhasilan pengobatan yaitu penggunaan obat yang rasional. Penelitian ini bertujuan untuk mengetahui apakah pemakaian obat TB di Puskesmas Pangkalan Susu Kecamatan Pangkalan Susu Kabupaten Langkat Sumatera Utara sudah rasional atau belum. Penelitian ini dilakukan dengan metode pengambilan data dari rekam medis pasien TB paru di Puskesmas Pangkalan Susu. Total sampel 24 orang pasien TB paru selama tahun 2019. Hasil penelitian menunjukkan bahwa ketepatan penggunaan obat Anti Tuberkulosis di Puskesmas Pangkalan Susu Kecamatan Pangkalan Susu Kabupaten Langkat Sumatera Utara pada periode 2019 yaitu tepat indikasi 100%, tepat pasien 100%, tepat pemilihan obat 100%, tepat lama pemakaian obat 95,83% dan tepat dosis 100%.
Kata kunci: Tuberkulosis, Obat Anti Tuberkulosis, Pasien TB, Rasional
PROFIL PENGGUNAAN OBAT ANTIHIPERTENSI PADA PERIODE SEPTEMBER 2019 SAMPAI DENGAN SEPTEMBER 2020 DI RSUD KOTA PINANG
Authors: Sylvia Br. Ginting Ovalina , Pasaribu Khairinah 
Published: December 2021

Hipertensi masih menjadi penyakit kardiovaskular yang sampai saat ini prevalensinya diperkirakan terus bertambah di seluruh dunia. Hipertensi perlu mendapat perhatian khususnya dalam sistem pelayanan kesehatan dibidang farmasi dengan menjamin tersedianya obat-obatan. Tujuan penelitian ini adalah untuk mengetahui presentase Obat Antihipertensi pada Periode September 2019 sampai dengan September 2020 di RSUD Kota Pinang. Penelitian ini merupakan penelitian restrospektif. Populasi dalam penelitian ini adalah seluruh pasien hipertensi yang berobat di RSUD Kota Pinang pada periode Bulan September 2019 sampai dengan September 2020 sebanyak 492 orang berdasarkan data rekam medik di RSUD Kota Pinang. Pengambilan sampel menggunakan Simple Rando sampling sebanyak 83 orang. Obat antihipertensi adalah obat – obatan yang digunakan untuk mengobati hipertensi di RSUD Kota Pinang seperti candesartan 8 mg, candesartan 16 mg, Amlodipine 5 mg, Amlodipine 10 mg, Lisinopril 5 mg, Lisinopril 10 mg, captopril 12,5 mg dan Captopril 25 mg. Berdasarkan hasil penelitian didapatkan bahwa Profil Pasien di RSUD Kota Pinang adalah sebagian besar umur 61-70 Tahun, jenis kelamin sebagian besar perempuan, jenis perawatan sebagian besar adalah rawat jalan dan klasifikasi hipertensi sebagaian besar adalah sedang, Jenis Obat Antihipertensi yang digunakan di RSUD Kota Pinang Periode September 2019 sampai dengan September 2020 adalah candesartan 8 mg, candesartan 16 mg, Amlodipine 5 mg, Amlodipine 10 mg, Lisinopril 5 mg, Lisinopril 10 mg, captopril 12,5 mg dan Captopril 25 mg dan Presentase Obat Antihipertensi yang sering diresepkan pada Periode September 2019 sampai dengan September 2020 adalah Amlodipine 10 mg. Saran dalam penelitian diharapkan menjadi referensi awal dalam melanjutkan penelitian yang sama serta menambah variabel penelitian agar penelitian tersebut dapat semakin akurat.

Kata kunci: Obat Antihipertensi
O USO DAS GEOTECNOLOGIAS COMO FERRAMENTA DE AUXÍLIO NA ANÁLISE AMBIENTAL NO MUNICÍPIO DE JATAÍ GOIÁS
Authors: Cabral Souza Carine , Cristina da Cunha Márcia 
Published: December 2021

Resumo – As geotecnologias têm ocupado espaço no cenário mundial de forma a se expandir em diversas ciências, principalmente as que se preocupam com questões ambientais. As geotecnologias são importantes na realização de tarefas enquanto geográficas, e vem sendo aplicadas por profissionais atuantes na área. Portanto, o objetivo principal deste trabalho foi verificar quais são as principais geotecnologias utilizadas como ferramenta de auxílio na análise ambiental no município de Jataí-Goiás, Brasil. Como metodologia utilizada, baseamos no levantamento bibliográfico e na pesquisa em campo por meio de banco de dados espaciais. Incidimos também na obtenção de dados primários por meio de levantamento in loco em empresas e instituições públicas e privadas, para isso houve a aplicação de um questionário semiestruturado. Como resultado notamos que as geotecnologias mais utilizadas na análise ambiental em Jataí são: GNSS, Estação Total, Nível, Drone, Ploter, Bússola, Teodolito, Google Earth PRO, ArcGIS, AutoCAD, Topograph, MetricaTOPO, Qgis, Spring, Track Maker, DataGeosis e TopoEVN. Nos sites levantados em relação ao uso do banco de dados por meio das Geotecnologias estão entre os principais: SIEG, INPE, INMET. Concluímos, que as geotecnologias utilizadas como ferramenta de auxílio na análise ambiental são de suma importância para a eficácia dos trabalhos realizados no monitoramento ambiental.
Palavras-chave: Informações espaciais, agilidade, profissionais.
UJI STABILITAS SEDIAN LOTION ANTINYAMUK DENGAN VARIASI KONSENTRASI EKSTRAK BUNGA SUKUN (Artocarpus altilis) TERHADAP NYAMUK AEDES AEGYPTI
Authors: Setiawan Prayitno , Farid Nurfiddin , Yusuf Muhammad , Latelay Rio Markasi 
Published: December 2021

Bunga sukun diketahui memiliki kandungan senyawa flavonoid yang dapat dimanfaatkan sebagai antinyamuk. Tujuan penelitian ini untuk mengetahui basis formula sediaan lotion dari ekstrak bunga sukun (Artocarpus altilis)yang stabil secara fisik sebagai antinyamuk dan untuk mengetahui efektivitas variasi konsentrasi ekstrak dari formulasi lotion ekstrak bunga sukun sebagai antinyamuk. Metode penelitian ini merupakan penelitian eksperimental. Lotion antinyamuk ekstrak dibuat dalam 4 kelompok formula yaitu kelompok formula 1 konsentrasi konsentrasi 20%, kelompok formula 2 dengan konsentrasi 30%, kelompok formula 3 konsentrasi 40%, kelompok kontrol negativ tanpa menggunakan ekstrak dan kontrol positif dengan menggunakan lotion merek (Autan). Hasil Evaluasi kestabilan fisik sediaan lotion antinyamuk pada pengujian organoleptik, pH, homogenitas tidak terjadi perubahan kestabilan selama proses sebelum dan sesudah cycling test. Uji efek lotion menggunakan 100 ekor nyamuk (Aedes aegypti) yang dibagi dalam 5 kelompok perlakuan yang terdiri dari 20 ekor nyamuk, pengujian dilakukan tiga kali pengulangan dengan selang waktu 5 menit. Hasil penelitian menunjukan lotion antinyamuk ekstrak kosentrasi 20% dapat memberikan efek daya tolak nyamuk dilihat dari uji SPSS versi 24 menunjukan p>0,05 sehingga tidak ada perbedaan secara bermakna dengan kontrol positif. Hal tersebut dapat disimpulkan ekstrak bunga sukun memilik efek sebagai antinyamuk pada konsentrasi 20% terhadap nyamuk uji.Kata kunci: Bunga Sukun, Lotion, Nyamuk, Antinyamuk
Comparación de los adhesivos Single Bond TM Universal y Adper TM Single Bond 2 contra la microfiltración en restauraciones Clase II obturadas con resina Bulk Fill
Authors: CLAROS JALDIN GABRIEL ANDRE , Zamorano Vilar Cinthya Fabiola , Cáceres Sánchez Liliana 
Published: December 2021

RESUMEN
Introducción: Los sistemas adhesivos son parte muy importante para la rehabilitación oral, es por esto que el profesional debe estar constantemente actualizado con nueva información sobre los más recientes productos comercializados.
Objetivo: Determinar el grado de microfiltración marginal gingival en cavidades clase II, obturadas con la resina FiltekTM Bulk Fill (de incremento único), comparando 2 distintos sistemas adhesivos; el primero el adhesivo Single BondTM Universal (autograbante), sin grabado ácido y el segundo el adhesivo AdperTM Single Bond 2, con grabado ácido total.
Metodología: Se efectuó un trabajo prospectivo, analítico y transversal para evidenciar la microfiltración marginal gingival. Se utilizaron 25 piezas dentales posteriores, molares y premolares. Se aplicaron 2 preparaciones cavitarias estandarizadas clase II, sin cajón oclusal, ubicadas en caras proximales (mesial-distal), posteriormente ambas preparaciones fueron obturadas con resina FiltekTM Bulk Fill utilizando 2 sistemas adhesivos: el Single BondTM Universal (autograbante), sin grabado ácido; y el adhesivo AdperTM Single Bond 2 con grabado ácido total. Las muestras fueron sometidas a 200 ciclos de termociclado en una solución de azul de metileno al 1%, posteriormente fueron cortadas para evidenciar la microfiltración marginal.
Resultados: Se demostró que empleando ambos sistemas adhesivos existió microfiltración marginal; se encontró mayor microfiltración con el adhesivo Single BondTM Universal (autograbante) con un promedio de 44,7%; comparado al obtenido con el adhesivo AdperTM Single Bond 2, que tuvo un valor promedio de microfiltración de 26%; con promedios de microfiltración de 1,78 ± 1,25mm y 1,06 ± 1.16mm, respectivamente. El adhesivo AdperTM Single Bond 2 obtuvo un número de 10 muestras de 25, que no mostraron microfiltración alguna, contrastando con un número de 3 muestras de 25 sin microfiltración, con el adhesivo Single BondTM Universal (autograbante).
Conclusión: Se encontró una diferencia en el grado de microfiltración marginal a favor del sistema adhesivo AdperTM Single Bond 2, obteniendo este menor porcentaje en comparación con el sistema adhesivo Single Bond Universal, en su modalidad autograbante.
John Steinbeck and Korean Connections
Authors: Kim Wook-Dong 
Published: December 2021

Abstract
Compared to John Steinbeck's unusually great popularity in Japan, his popularity in South Korea has been regrettably scanty. The Twenty-Ninth International PEN Congress held in Tokyo in August 1957, however, paved the way for the proper introduction of Steinbeck to South Korea on a much greater scale. In-sob Zong's interview with Steinbeck in Tokyo played a central role in making the obscure American writer widely known to Korean readers. The topics discussed in the brief interview include (1) the negative impact of mass media, such as radio, television, and advertisements, on literary artists; (2) the extent to which American writers think and write freely; (3) the role of the writer as a social or political critic; and so on. In addition, this article examines how strenuously Steinbeck tried to fight vicious Communist propaganda with regard to United Nations forces allegedly dumping germs in the Korean peninsula during the Korean War. It also maintains that Steinbeck was greatly concerned with Korea and its civil war. His bedrock conviction for the future of Korea and its people is best articulated in a series of letters he wrote to Alicia Patterson, publisher of Newsday, in 1965–67.
Productividad y Función de Producción de Ingeniería para la Producción de Glucosiltransferasa por Fermentación
Authors: Paredes-Lizárraga Marco Antonio 
Published: December 2021

Se presenta un modelo de función de producción de ingeniería para modelar la producción de glucosiltransferesa por fermentación, con el objetivo de determinar la máxima producción, máxima productividad y elasticidad unitaria. A los datos del primer DOE publicados por Kawaguti et al. (2005) se les aplicó el método de regresión estadística restringida (con R2 =0.981, P=001) y optimización restringida en el software Excel® Solver®. Para fermentar, se utilizó melaza de caña (X1 gL-1), licor de maíz (X2 gL-1) y levadura (X3 gL-1) Erwinia Sp. en cantidades identificadas por el vector de insumos X=(X1, X2, X3). Para cada combinación óptima seleccionada, los pronósticos para producción de glucosiltransferasa, costo por experimento y productividad son: producción óptima en (129.39, 72.897, 16.77) con 5.78 UmL-1, $0.74 y 7.75 UmL-1$-1 respectivamente; para productividad máxima en (118.39, 42,14, 4) con 4.56, $0.31 y 14.48; para productividad óptima (elasticidad unitaria y rendimientos constantes) en (102.44, 36.48, 3.46) con 4.01, $0.27 y 14.73. Los rendimientos de escala y elasticidad inducen a explorar el vector (102.56, 36.52, 3.47) como centro del próximo diseño experimental secuencial, tal que en este diseño se logre una mejor aproximación a los rendimientos constantes y una productividad óptima global.
A view of global monsoons in observed and model climatology
Authors: SAHA K.R. , DOOL HUUG M. VAN DEN , SAHA SURANJANA 
Published: December 2021

A 17 - year (1979-95) January and July climatology obtained from a T 62/ 28 -level version of the National Centers for Environmental Prediction (NCEP) global spectral operational model is compared with a mean observed climatology for the same period obtained from its reanalysis project, with a view to finding out how well it captures some of the well-thrown characteristics of the global monsoon circulation generated seasonally by differential heating of the earth's surface by the sun in the course of its annual oscillation about the equator. Good correspondence between the two is found in the fields of mean monthly anomaly (deviation of monthly mean from the annual mean) of surface temperature, surface pressure, atmospheric circulation and total rainfall over most parts of the globe, barring a few exceptions mostly in circulation and rainfall.

Large diversity in the distribution and intensity of monsoon found over different regions due to land-sea configurations, cold and warm ocean surfaces and high mountain ranges appears to be well reflected in model and observed climatology. However, the concept of a single equatorial trough moving from one hemisphere to the other to cause advance and onset of monsoon appears to fail especially over warm oceans, where there appears to be evidence in favour of two troughs, one in each hemisphere. It is the equatorial trough in the summer hemisphere that moves to bring up the monsoon in that hemisphere. There appears to be some evidence to suggest an east-west movement of monsoons between major continents and oceans.
A study on the characterization of monsoon rainfall for sorghum (Sorghum Vulgare Pers) and its response to typical rainfall patterns
Authors: GHADEKAR S. R. , MISKIN R. B. 
Published: December 2021

Twenty eight years (1962-89) rainfall of Nagpur was analysed and the rainfall suitability at various probability levels for sorghum crop was studied. The total rainfall during kharif season (25-39th MW) was 861.50 mm. Normal rainfall/week exceeded 50 mm during 12 weeks (25-36th MW) which declined successively for three week (37-39th MW). The coefficient of variation (CY) ranged between 74.3% (25th MW), to 144.7% (39th MW). The rainfall at 50% probability level was well distrturbed during 12 week (25-36th MW)-ranging between 44.5 to 36.3 mm being adequate and sufficient (>20 mm/week) for sorghum crop considering its weekly demand (21-35 mm/week).
Typical rainfall patterns representing the situation were defined on the basis of their repetitiveness. Out of four typical rainfall patterns studied the one with lowest rainfall (458.4 mm /season and 30.56 mm/week) fetched the highest yield (865.0 kg/ha) which ensured adequate rains during the various growth stages except maturity. Excessive rainfall (>l00 mm/week) and deficient rainfall <20 mm/week) during every stage were inadequate. Rainfall atleast 30.56 mm/week was most adequate.
Dynamic rain model for linear stochastic environments
Authors: RITTER WALTER , MOSINO PEDRO , BUENDIA ENRIQUE 
Published: December 2021

To develop modem agriculture, a vision of an integral management is required, where the complexity of interactions between climatic, biological, economical, social and political factors involved in the food production must systematically be analyzed in a context of regional conditions.

At the same time, it is necessary to develop the ability to forecast both the climatic variations and their possible impact on society. The minimization of this impact on agriculture through consistent practices adequate to local climates, is not only commendable, but basically necessary, besides, the usefulness of these studies in acquiring a better knowledge of those areas with an inversion risk for agricultural and cattle rising development is high.

In this paper a statistical model is used to accomplish the objectives above mentioned. The rainfall variability in several areas of the Tlaxcala State (Mexico) is analyzed with due regard to both inter- and intra-annual relations, considering that the cumulative rainfall, in the former case, follows a logistic curve and in the latter it follows a linear, first order, stochastic process.
Upper troposphere circulation anomalies over Asia-Pacific region associated with the interannual variation of Indian summer monsoon
Authors: PAI D. S. , RAJEEVAN M. , DE U. S. 
Published: December 2021

Monthly mean vector wind and geopotential heights at 200 hPa of 67 radiosonde stations from Asia Pacific regions for the period 1963-1988 are used to examine the composite circulation anomaly patterns for the month of May and the monsoon season (June- September) with respect to good monsoon years and bad monsoon years (both associated with ENSO and not associated with ENSO). There are significant differences in the anomalous circulation features between good and bad monsoon years. During the month of May an anomalous anticyclonic (cyclonic) circulation over-central Asia and an anomalous cyclonic (anticyclonic) circulation over Pacific ocean were observed during good (bad) monsoon years. These anomalies persist in the subsequent monsoon season. The key mechanisms of the development of these anomalous circulation patterns and their consequences are discussed.