bluuebunny/crossref_metadata_2025_split huggingface dataset:
MENOPAUSAL HORMONAL THERAPY AND BREAST CANCER
Authors: Бахидзе Е.В. , Беляева А.В. , Берлев И.В. , Анисимов В.Н. , Беляев А.М. 
Published: August 2021

Наиболее распространенным методом лечения климактерического синдрома является менопаузальная гормональная терапия (МГТ), однако безопасность ее применения, в связи с риском развития и рецидива рака молочной железы (РМЖ), до сих пор является предметом дискуссии. В обзоре приводятся результаты рандомизированных контролируемых исследований этой проблемы. Показано, что МГТ повышает риск развития РМЖ и рецидива заболевания после лечения. Риск РМЖ, развивающегося у женщин, получающих МГТ, зависит от ИМТ, длительности приема и дозы препаратов и выше у худых женщин, чем у женщин с повышенным ИМТ, а также выше у женщин, принимающих комбинированную МГТ (эстроген и прогестаген), по сравнению с женщинами, принимающими только эстрогенную терапию. Обнаружено, что у женщин, принимавших МГТ, чаще развивались гормонозависимые формы рака, но к моменту диагностики заболевания выявлялись более распространенные стадии и чаще обнаруживались метастазы в лимфатические узлы по сравнению с женщинами, не принимавшими МГТ. Риск рецидива РМЖ меньше при применении низких доз вагинального эстрогена. Альтернативным вариантом купирования менопаузальных расстройств у пациенток на фоне и после лечения РМЖ может стать применение гормона эпифиза мелатонина, поскольку наряду с его геропротекторными свойствами он способен подавлять рак на этапах инициации, прогрессирования и метастазирования и обладает способностью уменьшать токсические последствия противоопухолевых препаратов при одновременном повышении их эффективности.
The most common treatment for menopausal syndrome is menopausal hormone therapy (MHT), however, the safety of MHT, due to the risk of developing and recurrent breast cancer (BC), is still a matter of debate. The review presents the results of randomized cohort studies of this issue. It has been shown that MHT increases the risk of developing of breast cancer and disease recurrence after treatment. Risk of breast cancer developing in women getting MHT, depends on body mass index (BMI), duration of hormone use and dose of drugs, and is greater in thin women comparing with women with increased BMI, and also greater in estrogen-progestin combined MHT users comparing with estrogen-only users. It was found that in women using MHT hormone-dependent forms of cancer developed more often, but by the time of diagnosis, disease was found in more advanced stage and metastases in lymph nodes were found more often comparing with patients who did not use MHT. Risk of breast cancer recurrence is less with the use of low doses of vaginal estrogen. An alternative option for the relief of menopausal disorders in breast cancer patients during and after treatment is using of pineal gland hormone melatonin, since, along with its anti-aging properties, it is able to suppress cancer at the stages of initiation, progression and metastasis and has the ability to reduce the toxic effects of anticancer drugs while increasing their effectiveness.
AGING FOOT SYNDROME: PATIENTS SCREENING AND ROUTING
Authors: Горелик С.Г. , Ильницкий А.Н. , Прощаев К.И. , Осипова О.А. , Бутикова Е.С. , Фесенко Э.В. 
Published: August 2021

В статье показано, что при оказании медицинской и социальной помощи пациентам старших возрастных групп целесообразно обращать внимание не только на наличие соматических заболеваний и общих гериатрических синдромов, но и проводить скрининг локальных гериатрических синдромов, таких как, в частности, синдром возрастной стопы, которые также влияют на функциональный статус пациентов. Применение скрининга синдрома возрастной стопы, маршрутизации пациентов, а также мер восстановительного лечения позволяют поддерживать на должном уровне состояние общей двигательной активности пациента и качества жизни.
The article proves that when providing medical and social care to patients of older age groups, it is advisable to pay attention not only to the patients’ somatic and geriatric status, but also to perform screening of local geriatric syndromes that affect the patients’ functional status, such as, in particular, aging foot syndrome. Implementation of rehabilitation treatment measures that we propose allows to maintain the patients’ mobility level and consequently their general functional capability level and quality of life.
RELATIONSHIP OF KIDNEY FUNCTIONS WITH GERIATRIC SYNDROMES IN ELDERLY AND OLD WOMEN
Authors: Курмаев Д.П. , Булгакова С.В. , Захарова Н.О. , Тренева Е.В. , Николаева А.В. 
Published: August 2021

На фоне старения происходит увеличение числа заболеваний, ассоциированных с возрастом, гериатрических синдромов, способствующих развитию нарушений физической и функциональной активности, усиливается риск инвалидизации и смертности. Одним из широко распространенных заболеваний является ХБП, которая опасна не только сама по себе, но и как фактор прогрессирования других возраст-ассоциированных заболеваний и гериатрических синдромов, в том числе старческой астении и саркопении. У пациентов старших возрастных групп ХБП чаще встречается у женщин, чем у мужчин. Ряд исследователей изучают проблемы полиморбидности, развитие и прогрессирование гериатрических синдромов у пациентов с ХБП додиализной и диализной стадий. Несомненна отрицательная роль тяжелых поздних стадий ХБП в развитии старческой астении и саркопении, в то же время связь этих гериатрических синдромов с ранними додиализными стадиями ХБП изучена недостаточно. Поэтому представляет несомненный научный интерес выявление корреляции признаков саркопении и старческой астении у женщин пожилого и старческого возраста в зависимости от функции почек, стадии ХБП.
Against the background of aging, there is an increase in the number of diseases associated with age, geriatric syndromes that contribute to the development of disorders of physical and functional activity, the risk of disability and mortality increases. One of the widespread diseases is chronic kidney disease (CKD), which is dangerous not only in itself, but also as a factor in the progression of other age-associated diseases and geriatric syndromes, including frailty and sarcopenia. Among patients of older age groups, CKD is more common in women than in men. A number of researchers are studying the problems of polymorbidity, the development and progression of geriatric syndromes in patients with CKD in the pre-dialysis and dialysis stages. Undoubtedly, the negative role of severe late stages of CKD in the development of senile asthenia and sarcopenia, at the same time, the relationship of these geriatric syndromes with early pre-dialysis stages of CKD has been insufficiently studied. Therefore, it is of undoubted scientific interest to identify correlations between signs of sarcopenia and frailty in elderly and senile women, depending on renal function, stage of CKD.
INDICATORS OF ORAL FLUID AND THEIR CORRECTION BY MEANS OF HYGIENE IN ELDERLY PEOPLE WITH GENERAL SOMATIC DISEASES
Authors: Улитовский С.Б. , Алексеева Е.С. , Васянина А. А. , Калинина О.В. , Ермолаева Л. А. 
Published: August 2021

Приведены результаты исследования ротовой жидкости у лиц старшего возраста с соматической патологией, наблюдение за которыми проводили на протяжении 1 мес. Оценивали кислотно-осно' вное состояние ротовой жидкости, определяли вязкость ротовой жидкости. По результатам исследования ротовой жидкости и ее коррекции средствами гигиены у лиц старшего возраста с соматическими заболеваниями отмечали динамику показателей кислотно-осно'вного состояния ротовой жидкости, его сдвиг в щелочную сторону и положительную динамику состояния вязкости ротовой жидкости. Для обеспечения снижения риска неблагоприятных воздействий при изменении состояния ротовой жидкости необходим совместный подход с участием всех медицинских работников, учитывающий детерминанты здоровья и обеспечивающий разработку эффективных методов профилактики стоматологических заболеваний у лиц старшего возраста.
The results of the study of oral fluid in older persons with somatic pathology, which was followed for 1 month, are presented. The acid-base state of the oral fluid was evaluated, and the viscosity of the oral fluid was determined. According to the results of the study of oral fluid and its correction by means of hygiene in older persons with somatic diseases, the dynamics of the indicators of the acid-base state of the oral fluid, its shift to the alkaline side and the positive dynamics of the effect of the viscosity of the oral fluid were noted. To ensure that the risk of adverse effects from changes in the state of the oral fluid is reduced, a joint approach involving all health professionals is needed, taking into account the determinants of health and ensuring the development of effective methods for the prevention of dental diseases in older persons.
SOME ASPECTS OF IMPROVING THE MEDICAL AND SOCIAL REHABILITATION OF THE ELDERLY WHO PERMANENTLY LIVE IN GENERAL-TYPE BOARDING SCHOOLS
Authors: Меметов С.С. , Кобзев Ю.В. , Петрова В.Н. , Ким В.В. , Середа А. Н. 
Published: August 2021

В статье изучена потребность пожилых лиц и инвалидов, постоянно проживающих в учреждении социального обслуживания с круглосуточным пребыванием, в мерах по медико-социальной реабилитации с учетом возрастнополовой структуры контингента, наличием группы инвалидности и индивидуальных программ реабилитации (абилитации) инвалида. Установлена необходимость совершенствования мер по медико-социальной реабилитации, обеспечению и совершенствованию трудовой занятости в условиях учреждений и развитию их досуга, что позволит значительно повысить качество жизни этого контингента лиц. Приведены примеры положительного опыта работы в этом направлении в других регионах РФ.
The article reflects the age and gender structure of the contingent of elderly people living in a General boarding house. The most common diseases in this category of persons, the presence of a disability group and individual programs for rehabilitation (habilitation) of the disabled person were established. The need for medical care, including medicines, was studied. There is a need to improve measures for medical and social rehabilitation, including in improving the employment of this contingent of people and the development of their leisure time. Examples of positive experience in this area among other regions of the Russian Federation are given.
Segregation control for ultrathin Ge layer in Al/Ge(111) system
Authors: Ohta Akio , Kobayashi Masato , Taoka Noriyuki , Ikeda Mistuhisa , Makihara Katsunori , Miyazaki Seiichi 
Published: August 2021

Abstract
An impact of the vacuum anneal of Al/Ge(111) structure on the Ge segregation has been investigated to get an insight into the precise control of ultrathin Ge crystalline growth. The Al/Ge(111) structure was prepared by thermal evaporation of Al on wet-cleaned Ge(111) and then vacuum annealed without air exposure to promote Ge formation on the Al surface. The Ge formation and its chemical bonding features were evaluated by X-ray photoelectron spectroscopy analysis. In addition, changes in the average Ge thickness depending on annealing temperature and time were crudely estimated. We found that the annealing temperature had a greater effect than time on the control of sub-nanometer scale Ge growth.
InGaN-based red light-emitting diodes: from traditional to micro-LEDs
Authors: Zhuang Zhe , Iida Daisuke , Ohkawa Kazuhiro 
Published: August 2021

Abstract
InGaN-based LEDs are efficient light sources in the blue–green light range and have been successfully commercialized in the last decades. Extending their spectral range to the red region causes a significant reduction in LED efficiency. This challenge hinders the integration of red, green, and blue LEDs based on III-nitride materials, especially for full-color micro-LED displays. We review our recent progress on InGaN-based red LEDs with different chip sizes from hundreds to tens of micrometers, including the epitaxial structures, device fabrication, and optical performance (peak wavelength, full-width at half-maximum, light output power, efficiency, temperature stability, and color coordinates).
Perbaikan Keandalan Sistem Distribusi
Authors: Muhtar Ali , Baqaruzi Syamsyarief 
Published: August 2021

Energi listrik merupakan komoditi utama untuk menunjang kehidupan manusia di era digital saat ini. Penyaluran energi listrik dilakukan melalui pusat pembangkit besar di sejumlah lokasi. Sejak tiga dekade terakhir, terdapat banyak penelitian yang memfokuskan pada penggunaan DG untuk minimasi kerugian jarigan dan regulasi tegangan namun, sedikit yang memfokuskan kepada keandalan dari sistem jaringan distribusi energi listrik. Penelitian ini bertujuan untuk mengetahui dampak yang dihasilkan jika mengkoneksikan DG ke jaringan distribusi energi listrik. Data uji yang digunakan adalah system distribusi radial IEEE 33-bus. Algoritma PSO digunakan sebagai optimasi penentuan lokasi dan kapasitas dari DG. Hasil penelitian menunjukkan bahwa terdapat perbedaan system jaringan distribusi radial tanpa DG, dengan 1 DG dan 2 DG. Total rugi-rugi system distribus tanpa DG adalah 208,52 KW dan 334,38 KVAr, sedangkan 1 DG menghasilkan rugi-rugi 1,94% dari total rugi-rugi dan 2 DG menghasilkan 1,09% dari total rugirugi. Indicator keandalan system SAIDI tanpa DG yakni 4,7 jam/pelanggan.tahun dan mengalami perbaikan sebesar 27% dengan 2 DG. Sedangkan, inkator keandalan system SIAFI tanpa DG yakni 1,47 frekuensi/pelangggan.tahun mengalami perbaikan sebesar 4% dari dengan 2 DG. Sehingga dapat disimpulkan bahwa penambahan DG dengan algoritma optimasi PSO menunjukkan hasil berupa pengurangan rugi-rugi, perbaikan profil tegangan disetiap bus, serta perbaikan keandalan sistem distribusi.
Monitoring Kekenyalan Tahu Kedelai dengan Sensor Kapasitif Menggunakan Mikrokontroller Berbasis Android
Authors: Nur Laili Rizki Putri , Soelistianto Farida Arinie Soelistianto Arinie , Zakaria Nanak , Hidayati Nurul 
Published: August 2021

Tofu has the best quality vegetable protein because it has the most complete amino acid composition and is believed to have high digestibility (85% -98%). According to SNI 01-3142-1998 and SII No. 0270-1990 testing criteria for soy tofu based on smell, taste, color, appearance, or texture. Tofu soybeans are prone to physical or texture damage due to factors such as inappropriate pH levels and insufficient storage which results in damaged tofu. Therefore in this study, it is proposed to determine the elasticity of soy tofu with the parameters tested are the pH level in the manufacture of soy tofu, the storage temperature, and the capacitance value to see how thick the tofu is with a capacitive sensor using the capacitor principle. Where the parallel plate capacitor is a capacitor consisting of two parallel metal plates. The test results of all sensors are sent to the database and will be displayed on the page on the Android application which will provide real-time sensor output information to the user. Based on the results of testing on this system using a pH sensor, the pH value is around 3-4 which indicates that the pH level used is very good for use in tofu processing, at pH 4.56 with storage at 29 ° C the highest elastic capacitance value is 3.58. In testing data delivery, the throughput value is 4336,217 b / s and the smallest delay value is 0.017ms because the smaller the delay value, the better the quality of data transmission because there will be no delay in sending data.
O estado pós-democrático
Authors: CARVALHO Cristiane da Costa 
Published: August 2021

Resenha sobre a obra “Estado Pós-Democrático, neo-obscurantismo e gestão dos indesejáveis” escrita em 2017 por Rubens Roberto Rebello Casara, que revela no título a constatação de que o Estado atual é posterior ao Estado democrático e não pode ser caracterizado como democracia. No decorrer dos capítulos o autor esclarece essa percepção, explica quem são os indesejáveis e em que consiste o “neo-obscurantismo”.
Análise do programa de controle do tabagismo em um municí­pio de médio porte do Paraná
Authors: Rodrigues Pires Graziele Adrieli , Bossolani Charlo Patrí­cia , Martins Marques Francielle Renata Danielli , Rocha Covre Eduardo , Paiano Marcelle , Aparecida Salci Maria 
Published: August 2021

Objetivo: Analisar os desfechos do tratamento para a cessação tabágica oferecido pelas Unidades Básicas de Saúde, inseridas no Programa de Controle do Tabagismo, de um municí­pio de médio porte do Estado do Paraná. Método: Pesquisa documental, descritiva, de abordagem quantitativa. Os dados utilizados incluí­ram os planos municipais e os documentos disponí­veis na Secretaria Municipal de Saúde do municí­pio do perí­odo de 2015 a 2019. Os resultados foram tabulados no Software Microsoft Excel 2016, analisados por estatí­stica descritiva e inferencial, aplicado o teste de qui-quadrado de Pearson com auxí­lio do ambiente estatí­stico EpiInfo versão 7.0. Resultados: Durante o perí­odo analisado, o municí­pio assistiu 2.339 usuários. Observou-se queda na procura e na efetividade do tratamento somado ao aumento nas taxas de abandono do tratamento. Conclusão: O municí­pio oferece atendimento í s pessoas tabagistas, conforme previsto pelo Programa Nacional de Controle do Tabagismo, contudo, apresenta fragilidades para que o mesmo ocorra de forma exitosa.
Percepções de pessoas com estomia intestinal acerca da sua qualidade de vida
Authors: Cardoso Silva Prisciane , Calcagno Gomes Giovana , Soares Mota Marina , Porto Gautério Daiane , Lopes dos Santos Fabiane , Portella Ribeiro Juliane 
Published: August 2021

Objetivos: conhecer a percepção de pessoas estomizadas intestinal acerca da sua qualidade de vida. Métodos: Estudo exploratório e descritivo de abordagem qualitativa. Realizado em um Serviço de Estomaterapia. Participaram do estudo 26 pessoas com estoma intestinal definitivo ou temporário com 18 anos ou mais. Os dados foram coletados em outubro e novembro de 2019, após aprovação do Comitê de ética em Pesquisa, sob parecer n°253/2019, por meio de questionário sociodemográfico e clí­nicos e entrevista semiestruturada. Os dados foram submetidos í Análise de Conteúdo. Resultados: A qualidade de vida de pessoas com estomia intestinal é afetada por complicações da estomia e as mudanças nos seus papéis sociais, bem como as alterações emocionais e fisiológicas decorrentes da estomização. Conclusões: Destaca-se que os efeitos positivos na qualidade de vida podem estar associados í forma como as pessoas reagem í sua própria estomia. A maioria dos participantes refere ter boa qualidade de vida.
URGENSI REGULASI PENYELENGGARAAN PERLINDUNGAN ANAK DI KABUPATEN KEDIRI
Authors: Djoko Siswanto  
Published: August 2021

Pada dekade ini perhatian pemerintahan dunia kepada anak-anak semakin besar dan karena disebabkan oleh adanya Deklarasi tentang Hak-hak Anak Internasional pertama kali diadopsi oleh Liga Bangsa-Bangsa sehingga dengan pengakuan atas hak-hak khusus yang dimiliki oleh anak secara historis di mana telah diakui sejak tahun 1924. Pemerintah Indonesia telah meratifikasi Konvensi Hak Anak melalui Keputusan Presiden Nomor 36 Tahun 1990 tentang Pengesahan Convention on The Rights of The Child (Konvensi tentang Hak-hak Anak). Konsekuensi logis dari dorongan dunia internasional di atas, suka dan tidak suka memberi inspirasi kepada pemerintah daerah, khususnya Pemerintah Kabupaten Kediri, Provinsi Jawa Timur, untuk menindaklanjuti dengan menyusun sebuah regulasi atau peraturan daerah tentang Penyelenggaraan Perlindungan Anak. Dalam penelitian ini digunakan metode penelitian yang dipergunakan adalah deskriptif dengan menggunakan instrumen penelitian kuesioner dengan ditambah wawancara untuk mengkonfirmasi semua informasi yang telah dikumpulkan dengan teknik kuesioner 38 (tiga puluh delapan) Organisassi Perangkat Daerah (OPD). Temuan yang dapat diidentifikasi dalam penelitian ini untuk dijadikan materi muatan regulasi peraturan daerahKabupaten Kediri adalah: (1) bagaimanakahhak-hak anak diakui oleh pemerintah dan lembaga sosial; (2)kewajiban orang tua dan keluarga, kewajiban pemerintah daerah ( 3) tanggung jawab pemerintah daerah, masyarakat, orang tua dan/atau keluarga, dunia usaha dan lembaga ( 4) perlindungan khusus anak; (5) penanganan korban (6) pengasuhan dan pengangkatan anak; (7) larangan; ( 8) kabupaten layak anak; (9) forum anak; (10 )sistem data dan informasi anak; (11) pembinaan, pengawasan, pelaporan; (12) peran serta; (13 ) koordinasi; (14 ) pembiayaan.
THE MEDIATING ROLE OF JOB SATISFACTION BETWEEN HUMAN RESOURCE DEVELOPMENT AND PROJECT SUCCESS
Authors: Rao Umair Aitimad Rao , Muhammad Saeed Shahbaz Muhammad Saeed Shahbaz 
Published: August 2021

ABSTRACT

Purpose - Human resource development (HRD) is considered one of the most important components for the success of any project. The purpose of this study is to examine the impact of HRD activities (career development and team development) on project success by inquiring into job satisfaction.
Insights into the crystal chemistry of the serandite–schizolite–pectolite series
Authors: Lussier Aaron J. , Grice Joel D. , Friis Henrik , Poirier Glenn G. 
Published: August 2021

ABSTRACT
The compositional series {Na} [[M1+M2](Ca2XMn2–2X)Si3O8(OH)] includes the minerals serandite (X = 0), schizolite (X = 0.5), and pectolite (X = 1). Six crystals are structurally and chemically characterized in detail (four from Ilímaussaq, Greenland; two from Mont Saint-Hilaire, Québec, Canada): one serandite, one pectolite, and four schizolite crystals. Those originating from Greenland show up to 0.05 apfu LREE3+ (La + Ce + Pr + Nd + Eu + Gd). For each, all H atoms were located, and final R1 factors were below 4.4% (&lt;R1&gt; = 2.35%). The results are compared with previously published crystal structure data from an additional 16 samples, originating from worldwide (mostly) igneous environments. Across the series, for all investigated samples, Ca and Mn order preferentially at the octahedral M1 and M2 sites, respectively, following the exchange M2Ca + M1Mn ↔ M1Ca + M2Mn. Site-occupancies closely adhere to a two-site distribution coefficient, calculated here to be K = 20.0(5), for ideal mixing where activity coefficients approach unity. For the above order-disorder exchange, ΔHex is calculated to be –1.77 kcal. With knowledge of K, site assignment and species determination may be accurately made solely with compositional data, where 0 ≤ ΣCa &lt; 0.55 apfu, serandite; 0.55 ≤ ΣCa &lt; 1.45 apfu, schizolite; and 1.45 ≤ ΣCa ≤ 2 apfu, pectolite, with the dominant-constituent rule mandating M1Ca &lt; M1Mn (M2Ca &lt; M2Mn), serandite; M1Ca &gt; M1Mn (M2Ca &lt; M2Mn), schizolite; and M1Ca &gt; M1Mn (M2Ca &gt; M2Mn), pectolite. Polyhedral distortion and structural strain at the M1 and M2 sites, calculated using the equations of Robinson et al. (1971) and solutions to Kirchhoff network equations, respectively, show a predictable, cooperative variation across the entire compositional series; however, prominent discontinuities in distortion and strain behavior are observed for the schizolite composition.