bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Use of the Oxygenated Airdrive<sup>TM</sup> Machine Perfusion System in Kidney Graft Preservation: A Clinical Pilot Study
Authors: Houtzager Julia H.E. , Hemelrijk Sebastiaan David , Post Ivo C.J.H. , Idu Mirza M , Bemelman Frederike J. , van Gulik Thomas M. 
Published: March 2021

<b><i>Background:</i></b> The shortage of donor kidneys has led to the use of marginal donors, e.g., those whose kidneys are donated after circulatory death. Preservation of the graft by hypothermic machine perfusion (HMP) provides a viable solution to reduce warm ischemic damage. This pilot study was undertaken to assess the feasibility and patient safety of the Airdrive<sup>TM</sup> HMP system in clinical kidney transplantation. <b><i>Methods:</i></b> Five deceased-donor kidneys were preserved using the oxygenated Airdrive HMP system between arrival at the recipient center (Amsterdam UMC) and implantation in the patient. The main study end-points were adverse effects due to the use of Airdrive HMP. Secondary end-points were clinical outcomes and perfusion parameters. All events occurring during the transplantation procedure or within 1 month of follow-up were monitored. <b><i>Results:</i></b> Five patients were included in this pilot study. No technical failures were observed during the preservation period using the Airdrive HMP. Mean perfusion parameters were: duration 8.5 h (3–15 h), pressure 25 mm Hg (18–25 mm Hg), flow 49.77 mL/min (19–58 mL/min), resistance 0.57 mm Hg/min/mL (0.34–1.3 mm Hg/min/mL), and temperature 8.2 °C (2–13°C). Mean cold ischemia time (CIT) was 20.2 h (11–29.5 h). No adverse events or technical failures were observed during preservation and transplantation or during the 1-month follow-up. <b><i>Conclusions:</i></b> This pilot study showed the feasibility of the use of the Airdrive HMP system with no adverse events in clinical kidney transplantation.
Potential Effects of Bariatric Surgery on the Incidence of Heart Failure and Atrial Fibrillation in Patients With Type 2 Diabetes Mellitus and Obesity and on Mortality in Patients With Preexisting Heart Failure: A Nationwide, Matched, Observational Cohort Study
Authors: Höskuldsdóttir Gudrún , Sattar Naveed , Miftaraj Mervete , Näslund Ingmar , Ottosson Johan , Franzén Stefan , Svensson Ann‐Marie , Eliasson Björn 
Published: March 2021

Background
Obesity and diabetes mellitus are strongly associated with heart failure (HF) and atrial fibrillation (AF). The benefits of bariatric surgery on cardiovascular outcomes are known in people with or without diabetes mellitus. Surgical treatment of obesity might also reduce the incidence of HF and AF in individuals with obesity and type 2 diabetes mellitus (T2DM).

Methods and Results

In this register‐based nationwide cohort study we compared individuals with T2DM and obesity who underwent Roux‐en‐Y gastric bypass surgery with matched individuals not treated with surgery. The main outcome measures were hospitalization for HF and/or AF and mortality in patients with preexisting HF. We identified 5321 individuals with T2DM and obesity who had undergone Roux‐en‐Y gastric bypass surgery between January 2007 and December 2013 and 5321 matched controls. The individuals included were 18 to 65 years old and had a body mass index >27.5 kg/m
2
. The follow‐up time for hospitalization was until the end of 2015 (mean 4.5 years) and the end of 2016 for death. Our results show a 73% lower risk for HF (hazard ratio [HR], 0.27; CI, 0.19–0.38), 41% for AF (HR, 0.59; CI, 0.44–0.78), and 77% for concomitant AF and HF (HR, 0.23; CI, 0.12–0.46) in the surgically treated group. In patients with preexisting HF we observed significantly lower mortality in the group who underwent surgery (HR, 0.23; 95% CI, 0.12–0.43).

Conclusions
Bariatric surgery may reduce risk for HF and AF in patients with T2DM and obesity, speculatively via positive cardiovascular and renal effects. Obesity treatment with surgery may also be a valuable alternative in selected patients with T2DM and HF.
Status Threat: Moving the Right Further to the Right?
Authors: Parker Christopher Sebastian 
Published: March 2021

Abstract
Over the last few years, right-wing movements have proliferated among Western democracies. Although much of the growth has taken place across the “pond” in Europe, this phenomenon is not confined to that continent. As recent events make clear, the United States is another major case. In this essay, I offer a theory of the emergence of reactionary movements, fueled by status threat, using the United States as a case. To demonstrate the explanatory range of the theory (and measure), I focus on immigration, impeachment, and support for Donald Trump in the 2020 election. Examining self-identified Republicans only, I argue that status threat motivates the reactionary wing of the GOP in the United States. Drawing on data culled from a national sample, I find support for my expectation that, beyond ideology and racism, status threat furnishes a new explanation for reactionary preferences. I close with a discussion of the implications.
Add Business and Stir
Authors: Blanchard Kathryn D. 
Published: March 2021

Abstract
This essay makes a case for teaching an interdisciplinary undergraduate course at the intersection of religion, ecology, and business. At a basic level, this approach gets students with diverse intellectual orientations and career interests in the same room; letting business and environmental studies majors work together on these questions fosters a variation on interfaith engagement. More deeply, it creates space for them to develop critical self-awareness about their own ethical commitments. The fact that no single instructor can be an expert in all three fields should not prevent us from stepping boldly into uncharted territory. The degradation of the earth is an interdisciplinary problem that requires interdisciplinary solutions, and each of us has something to contribute right now even if we cannot do it all. As teachers and lifelong learners, we can and must model intellectual humility even as we look for ways to take decisive individual and collective action.
Echoes of Plato’s Apology of Socrates in Luke-Acts
Authors: Reece Steve 
Published: March 2021

Abstract
As a literate and well-educated person, the author of the Gospel of Luke and the Acts of the Apostles (“Luke”) would have been familiar with Plato’s Apology of Socrates, one of the most widely-known ancient Greek texts in the Mediterranean world in the 1st century CE. Indeed, it appears that “Luke” may have used his, and his readers’, familiarity with stories about the life, trial, and death of Socrates, and with the account in Plato’s Apology of Socrates specifically, as an interpretive tool in three “trial” scenes narrated in Luke-Acts: those of Jesus, Peter, and, most obviously, Paul.
The Named Jew and the Name of God
Authors: Windsor Lionel J. 
Published: March 2021

Abstract
A connection between Paul’s charges against his interlocutor in Rom 2:21–22 and Josephus’s account of a notorious Jewish teacher in Rome (A.J. 18.81–84) is a catalyst for re-examining the purpose, topic, and argument of Rom 2:17–29. The foreground issue is not the soteriological status of Jews, but the effectiveness of typical Jewish law-based teaching to solve human foolishness, wickedness, and impiety. Paul reframes the discourse topic to demonstrate that typical Jewish law-based educational activity is ineffective in bringing about God’s glory among the nations. The interlocutor is thus a foil for Paul’s own eschatologically conceived apostolic ministry.
Size-related boldness is not altered by stomach flushing in a terrestrial salamander
Authors: Salvidio Sebastiano , Costa Andrea , Oneto Fabrizio 
Published: March 2021

Abstract
Animal personality is a relatively neglected field in amphibian research. In this study we assessed the influence of stomach flushing, a non-lethal technique used in amphibian dietary studies, on the boldness behaviour of the cave salamander Speleomantes strinatii. The time of emergence from a shelter located in an unfamiliar environment (a proxy for individual boldness) was measured in 26 cave salamanders before and after stomach flushing, while 14 non-flushed salamanders were tested as controls. Boldness was a repeatable behaviour for salamanders and larger individuals emerged from their shelter more rapidly than smaller ones. Linear mixed model analysis showed that flushing, sex and body condition had no effect on this behaviour. These findings are promising in the framework of the study of salamander personality. In particular, our results will be useful when exploring the relationship between individual trophic strategy and boldness, aggression or exploration behaviours in terrestrial salamanders.
Elsewhere and Otherwise
Authors: Toscano Alberto 
Published: March 2021

Abstract
This text introduces the symposium on Fredric Jameson’s Allegory and Ideology (2019), the second volume in his six-part The Poetics of Social Forms. It frames the debate with a brief exploration of some of the figures and problems of allegory that appear across Jameson’s œuvre, and surveys some of the Marxist conceptualisations of allegory that have shaped Jameson’s approach, as it straddles allegories of the commodity and allegories of utopia. The musical investigation of the nexus of allegory and affect, and the presentation of political allegory as primarily concerned with the disjunction between (national and international) levels are also touched upon as salient dimensions of Jameson’s theorising.
Antoine Lacassagne. De la chaire de Radiobiologie expérimentale (1941-1951) à la chaire de Médecine expérimentale (1951-1954)
Authors: Corvol Pierre 
Published: March 2021

Résumé
Il s’agit de la création de la chaire de Radiobiologie expérimentale, dont Antoine Lacassagne fut le titulaire de 1941 à 1951, et de sa transformation en chaire de Médecine expérimentale pour le même de 1951 à 1954. On étudie les rapports donnés à ces occasions : de Robert Courrier, professeur de Morphologie expérimentale et endocrinologie (1938-1966), présenté à l’assemblée des professeurs du 12 janvier 1941, d’Emmanuel Fauré-Frémiet, professeur d’Embryogénie comparée (1928-1954), ibid., puis la « Présentation des titres et travaux de Lacassagne, candidat à la chaire de Radiobiologie expérimentale », du même auteur, lue le 25 mai 1941. On dispose aussi d’un « Rapport en faveur d’une chaire de Médecine expérimentale », par Robert Courrier, présenté le 26 novembre 1950. L’ensemble montre la place de la recherche sur le cancer dans les chaires de Médecine du Collège de France, où le regroupement de disciplines s’est avéré être un terrain favorable à son essor.
La création de la chaire d’Histoire des religions au Collège de France (1880) : les rapports de Jules Soury et d’un savant anonyme [Ernest Renan]
Authors: Henriet Patrick 
Published: March 2021

Résumé
En 1880 fut créée au Collège de France une chaire d’Histoire des religions. Il s’agissait là d’un des moments forts de l’institutionnalisation de cette discipline en France. Il n’y eut pas alors d’élection, mais une nomination par le ministère. La presse rendit largement compte de l’affrontement entre les deux candidats. Jules Soury était alors le représentant d’un anticléricalisme virulent qui allait bien au-delà du catholicisme et qui affirmait que les religions étaient un archaïsme dont les sociétés évoluées finiraient par se débarrasser. Le pasteur Albert Réville, qui l’emporta, était quant à lui le représentant du protestantisme libéral. On conserve aux Archives Nationales deux rapports défendant l’opportunité de cette création. L’un est de Jules Soury lui-même. Quant à l’autre, anonyme, nous pensons pouvoir l’attribuer à Ernest Renan. Nous publions ces deux textes inédits avec des notes explicatives.
Rapid Warming of Sea Surface Temperature along the Kuroshio and the China Coast in the East China Sea during the Twentieth Century
Authors: Sasaki Yoshi N. , Umeda Chisato 
Published: March 2021

AbstractIt has been reported that the sea surface temperature (SST) trend of the East China Sea during the twentieth century was a couple of times larger than the global mean SST trend. However, the detailed spatial structure of the SST trend in the East China Sea and its mechanism have not been understood. The present study examines the SST trend in the East China Sea from 1901 to 2010 using observational data and a Regional Ocean Modeling System (ROMS) with an eddy-resolving horizontal resolution. A comparison among two observational datasets and the model output reveals that enhanced SST warming occurred along the Kuroshio and along the coast of China over the continental shelf. In both regions, the SST trends were the largest in winter. The heat budget analysis using the model output indicates that the upper-layer temperature rises in both regions were induced by the trend of ocean advection, which was balanced in relation to the increase of surface net heat release. In addition, the rapid SST warming along the Kuroshio was induced by the acceleration of the Kuroshio. Sensitivity experiments revealed that this acceleration was likely caused by the negative wind stress curl anomalies over the North Pacific. In contrast, the enhanced SST warming along the China coast resulted from the ocean circulation change over the continental shelf by local atmospheric forcing.
Assessing the Influence of Complex Terrain on Severe Convective Environments in Northeastern Alabama
Authors: Katona Branden , Markowski Paul 
Published: March 2021

AbstractStorms crossing complex terrain can potentially encounter rapidly changing convective environments. However, our understanding of terrain-induced variability in convective storm environments remains limited. HRRR data are used to create climatologies of popular convective storm forecasting parameters for different wind regimes. Self-organizing maps (SOMs) are used to generate six different low-level wind regimes, characterized by different wind directions, for which popular instability and vertical wind shear parameters are averaged. The climatologies show that both instability and vertical wind shear are highly variable in regions of complex terrain, and that the spatial distributions of perturbations relative to the terrain are dependent on the low-level wind direction. Idealized simulations are used to investigate the origins of some of the perturbations seen in the SOM climatologies. The idealized simulations replicate many of the features in the SOM climatologies, which facilitates analysis of their dynamical origins. Terrain influences are greatest when winds are approximately perpendicular to the terrain. In such cases, a standing wave can develop in the lee, leading to an increase in low-level wind speed and a reduction in vertical wind shear with the valley lee of the plateau. Additionally, CAPE tends to be decreased and LCL heights are increased in the lee of the terrain where relative humidity within the boundary layer is locally decreased.
Simple Endoscopic Application of Laryngeal Keel Stent
Authors: Sweed Ahmed Hassan , Mobashir Mohamed , Mohamed Abd Elraof Said , Elsayed Ahmed Ibrahim , Elmalt Ashraf , Elshora Mohamed Elsayed 
Published: March 2021

This study describes a simple extraendolaryngeal technique to apply laryngeal keel in dealing with anterior commissure web/fibrosis. Standard extraendolaryngeal punctures were applied via 20‐gauge needles, 30° from the skin surface, in midline through the cricothyroid and thyrohyoid membranes. These needles were used as a conduit for the passage of 2/0 Prolene threads, which were retrieved through the laryngoscope by crocodile forceps. Both laryngoscopic ends of the Prolene threads were passed through a fabricated silastic sheet (keel stent) via a 22‐gauge free needle, and these ends were tied to have a secure internal knot. Steady traction was applied on the other 2 external threads until there was appropriate application of this keel stent within the vicinity of anterior commissure. Finally, these external ends were tied to have a secure external knot. A keel stent could be applied without the need for special instrumentation and with reasonable outcomes (proper healing of anterior commissure, satisfied voice outcome, and patent airway).
A Marxian Reply to Hahnel: The Relative Explanatory Power of Marx’s Theory and Sraffa’s Theory
Authors: Moseley Fred 
Published: March 2021

This paper critically examines Robin Hahnel’s 2017 book Radical Political Economy: Sraffa versus Marx and especially compares the relative explanatory power of Marx’s theory and Sraffa’s theory. Hahnel’s book argues that Sraffa’s theory is superior to Marx’s theory with respect to the following six subjects: prices, profit, technological change, crises, the environment, and moral critique (each one considered in a separate chapter). This paper challenges Hahnel’s arguments on all six subjects and argues that Marx’s theory has greater explanatory power than Sraffa’s theory and continues to be the best critical theory of capitalism. JEL Classification: B24, B51
Effects of acupuncture versus cognitive behavioral therapy on brain-derived neurotrophic factor in cancer survivors with insomnia: an exploratory analysis
Authors: Liou Kevin T , Garland Sheila N , Li Q Susan , Sadeghi Keimya , Green Jamie , Autuori Isidora , Orlow Irene , Mao Jun J 
Published: March 2021

Introduction: Decreased brain-derived neurotrophic factor (BDNF) is associated with poor sleep. This study examined the effects of acupuncture versus cognitive behavioral therapy for insomnia (CBT-I) on serum BDNF and sleep outcomes in cancer survivors with insomnia. Methods: This was an exploratory analysis of a randomized clinical trial (n = 160) comparing acupuncture versus CBT-I for cancer survivors with insomnia. Interventions were delivered over 8 weeks. Outcomes were assessed at baseline and week 8. Serum BDNF was evaluated with enzyme-linked immunosorbent assay (ELISA). Sleep was evaluated with the insomnia severity index and consensus sleep diary. Pearson correlations between BDNF and sleep outcomes were calculated. Data analysis was limited to 87 survivors who provided serum samples. Results: Among 87 survivors, the mean age was 61.9 (SD: 11.4) years, 51.7% were women, and 24.1% were non-White. Mean serum BDNF did not significantly increase in acupuncture (n = 50) or CBT-I (n = 37) groups. When analysis was restricted to patients with low baseline BDNF (i.e. levels below the sample median of 47.1 ng/mL), the acupuncture group (n = 22) demonstrated a significant 7.2 ng/mL increase in mean serum BDNF (P = 0.03), whereas the CBT-I group (n = 21) demonstrated a non-significant 2.9 ng/mL increase (P = 0.28). Serum BDNF was not significantly correlated with sleep outcomes (all P > 0.05). Conclusion: Among cancer survivors with insomnia and low baseline BDNF, acupuncture significantly increased serum BDNF levels; however, the clinical significance of this finding requires further investigation. Trial registration no. NCT02356575 (ClinicalTrials.gov)
Cancer Survivorship Care in Colombia: Review and Implications for Health Policy
Authors: Franco-Rocha Oscar Yesid , Carillo-Gonzalez Gloria Mabel , Garcia Alexandra , Henneghan Ashley 
Published: March 2021

Introduction: The number of cancer survivors is increasing in Colombia, and health policy changes are necessary to meet their unmet needs and improve their health outcomes. Similar trends have been identified in developed countries, and positive changes have been made. Methods: We conducted a narrative review to provide an overview of Colombia’s social structure, health care system, and health care delivery in relation to cancer, with recommendations for improving cancer survivorship in Colombia based on the model of survivorship care in the United States. Results: We proposed general recommendations for improving cancer survivors’ care including (1) recognizing cancer survivorship as a distinct phase of cancer, (2) strengthening methods and metrics for tracking cancer survivorship, (3) assessing and monitoring cancer symptoms and quality of life of cancer survivors, (4) publishing evidence-based guidelines considering the social, economic, and cultural characteristics of Colombian population and cancer survivors’ specific needs. Conclusion: These recommendations could be used to inform and prioritize health policy development in Colombia related to cancer survivorship outcomes.
Exosomal miR-122-5p inhibits tumorigenicity of gastric cancer by downregulating GIT1
Authors: Jiao Yigang , Zhang Li , Li Jun , He Yuqi , Zhang Xin , Li Jingzhe 
Published: March 2021

Background: microRNAs (miRNAs) are non-coding RNAs with important roles in the progression of human cancers, including gastric cancer. Exosomes are extracellular vesicles, which could transfer numerous noncoding RNAs, such as miRNAs. Here, in our study, we intended to investigate the role of exosomal miR-122-5p in gastric cancer progression. Methods: Exosomes were isolated utilizing commercial kit or ultracentrifugation. Biomarkers of exosomes or epithelia-mesenchymal transition (EMT) were monitored by western blot. Expression levels of miR-122-5p and G-protein-coupled receptor kinase interacting protein-1 ( GIT1) were evaluated by quantitative reverse transcription-polymerase chain reaction (qRT-PCR) or western blot. Cell proliferation and apoptosis were assessed by colony formation assay, methyl thiazolyl tetrazolium assay and flow cytometry. Cell metastasis was evaluated via Transwell assay. The interaction between miR-122-5p and GIT1 was validated by dual-luciferase reporter assay. Furthermore, tumor growth in vivo was detected by xenograft assay. Results: Exosomes were successfully isolated. MiR-122-5p was downregulated in exosomes derived from the serum of gastric cancer patients. Exosomal miR-122-5p could hinder gastric cancer cell proliferation and metastasis in vitro and tumor growth in vivo. Knockdown of GIT1 also inhibited gastric cancer cell proliferation and metastasis. Exosomal miR-122-5p targeted GIT1 to alter cellular behaviors of gastric cancer cells. Conclusion: Exosomal miR-122-5p suppressed gastric cancer progression by targeting GIT1.
Epidemiology of Thyroid Carcinomas in North Macedonia (1999-2015)
Authors: Tanja Makazlieva , Olivija Vaskova , Sinisha Stojanoski , Nevena Manevska , Daniela Miladinova , Vesna Velikj Stefanovska 
Published: March 2021

Objective: We have set as objective to analyze epidemiological data of diagnosed thyroid carcinoma (TC) cases, incidence and prevalence rate by gender, age, histopathological type, and statistical regions in R. of N. Macedonia during the period 1999 to 2015. Material and Methods: Retrospective analysis of medical data collected from the 2 state thyroid departments. Inclusion criteria included newly diagnosed cases of TC in appropriate years for the period 1999 to 2015. We have evaluated: yearly incidence rate, incidence and prevalence by gender, age, the distribution in 8 statistical state regions and histopathological types and subtypes representation. Results: A total number of 422 TC patients were detected, average incidence rate of 1.22/105, with most prevalent papillary TCs79.5%, followed by follicular 10.9%, medullar 4.1%, anaplastic 3.1%, and other rare types with 2.3%. The highest incidence rate was detected in Skopje region, while the lowest in Southeast and the Polog region. The total prevalence rate for the female gender was 32.61/104 and for male 9.27/104 (f/m ratio = 3.52:1), with lowest female/male difference found in the elderly > 65 years (f/m = 2.21/1). Conclusion: Compared with regional epidemiological data we can conclude that Republic of N. Macedonia has very low incidence and prevalence rate, while female/male ratio was similar to that described in the literature. Our low incidence and prevalence rate may be due to 2 possible reasons, 1 would be insufficient diagnosis of only small portion of the real cases in the population, or the second reason may be a real low incidence resulting of specific etiopathogenetic circumstances.