bluuebunny/crossref_metadata_2025_split huggingface dataset:
Community norms of the Muscle Dysmorphic Disorder Inventory (MDDI) among gender minority populations
Authors: Nagata Jason M. , Compte Emilio J. , McGuire F. Hunter , Lavender Jason M. , Brown Tiffany A. , Murray Stuart B. , Flentje Annesa , Capriotti Matthew R. , Lubensky Micah E. , Obedin-Maliver Juno , Lunn Mitchell R. 
Published: July 2021

Abstract
Purpose
Representing the pathological extreme pursuit of muscularity, muscle dysmorphia (MD) is characterized by a pervasive belief or fear around insufficient muscularity and an elevated drive for muscularity. Despite evidence of heightened body image-related concerns among gender minority populations, little is known about the degree of MD symptoms among gender minorities, particularly based on Muscle Dysmorphic Disorder Inventory (MDDI) scores. The objective of this study was to assess community norms of the MDDI in gender-expansive people, transgender men, and transgender women.

Method
Data from participants in The PRIDE Study, an existing study of health outcomes in sexual and gender minority people, were examined. We calculated means, standard deviations, and percentiles for the MDDI total and subscale scores among gender-expansive people (i.e., those who identify outside of the binary system of man or woman; n = 1023), transgender men (n = 326), and transgender women (n = 177). The Kruskal-Wallis test was used to assess group differences and post hoc Dunn’s tests were used to examine pairwise differences.

Results
Transgender men reported the highest mean MDDI total score (30.5 ± 7.5), followed by gender-expansive people (27.2 ± 6.7), then transgender women (24.6 ± 5.7). The differences in total MDDI score were driven largely by the Drive for Size subscale and, to a lesser extent, the Functional Impairment subscale. There were no significant differences in the Appearance Intolerance subscale among the three groups.

Conclusions
Transgender men reported higher Drive for Size, Functional Impairment, and Total MDDI scores compared to gender-expansive people and transgender women. These norms provide insights into the experience of MD symptoms among gender minorities and can aid researchers and clinicians in the interpretation of MDDI scores among gender minority populations.
Development of prototype hat patterns for elderly women based on three-dimensional modeling
Authors: Jun Jungil , Ryoo Youngshil , Choi Kuengmi , Park Sunmi 
Published: July 2021

AbstractPopulation aging is a global phenomenon, and the elderly population has a higher economic capability today than that in the past. Thus, this population is considered to be a growing consumer group that enjoys both consumer and leisure life. In this study, we developed prototype hat patterns for elderly women that can be used for developing close-fitting hats, helmets, masks, and smart headwear. Three-dimensional (3D) head scan data of elderly women were employed herein, and the data were classified into three groups with common head size and head shape. The target group was selected from a high-frequency group among the classified groups, and a standard head form representing the target group was developed using averaging and wire frame generation techniques. Four hat types were considered, design baselines were developed for each type, and prototype patterns were designed for each hat type using a flattening technique. The suitability of the developed prototype hat patterns was subsequently verified. Our results showed that all four prototype patterns had errors less than 5 mm2 (1.40%). The hat patterning method proposed in this study is expected to improve the wearing comfort of high-value-added products designed for the elderly.
A relationship between the incremental values of area under the ROC curve and of area under the precision-recall curve
Authors: Zhou Qian M. , Zhe Lu , Brooke Russell J. , Hudson Melissa M. , Yuan Yan 
Published: July 2021

AbstractBackgroundIncremental value (IncV) evaluates the performance change between an existing risk model and a new model. Different IncV metrics do not always agree with each other. For example, compared with a prescribed-dose model, an ovarian-dose model for predicting acute ovarian failure has a slightly lower area under the receiver operating characteristic curve (AUC) but increases the area under the precision-recall curve (AP) by 48%. This phenomenon of disagreement is not uncommon, and can create confusion when assessing whether the added information improves the model prediction accuracy.MethodsIn this article, we examine the analytical connections and differences between the AUC IncV (ΔAUC) and AP IncV (ΔAP). We also compare the true values of these two IncV metrics in a numerical study. Additionally, as both are semi-proper scoring rules, we compare them with a strictly proper scoring rule: the IncV of the scaled Brier score (ΔsBrS) in the numerical study.ResultsWe demonstrate thatΔAUC andΔAP are both weighted averages of the changes (from the existing model to the new one) in separating the risk score distributions between events and non-events. However,ΔAP assigns heavier weights to the changes in higher-risk regions, whereasΔAUC weights the changes equally. Due to this difference, the two IncV metrics can disagree, and the numerical study shows that their disagreement becomes more pronounced as the event rate decreases. In the numerical study, we also find thatΔAP has a wide range, from negative to positive, but the range ofΔAUC is much smaller. In addition,ΔAP andΔsBrS are highly consistent, butΔAUC is negatively correlated withΔsBrS andΔAP when the event rate is low.ConclusionsΔAUC treats the wins and losses of a new risk model equally across different risk regions. When neither the existing or new model is the true model, this equality could attenuate a superior performance of the new model for a sub-region. In contrast,ΔAP accentuates the change in the prediction accuracy for higher-risk regions.
Preparation and performance of insect virus microcapsules
Authors: Luo Meng , Zhu Dandan , Lin Juntao , Zhou Xinhua , Zheng Changge , Pu Xia 
Published: July 2021

AbstractBackgroundBiological pesticides, especially baculovirus, often lose their activity under the influence of external light, temperature, and other changes. This limited the application of them. The present study was aimed to prolong the biological activity and ensure the efficacy of a biological pesticide using microencapsulation technology.ResultsIn this study, gelatin/carboxymethylcellulose (CMC)-Spodoptera lituranucleopolyhedrovirus microcapsules were prepared. The morphological characteristics, apparent morphology, embedding rate, virus loading, particle size, laboratory virulence, and UV resistance of the microencapsulated virus, were tested. The best conditions for preparing gelatin /CMC-S. lituranucleopolyhedrovirus microcapsules include the gelatin/CMC ratio of 9:1, wall material concentration of 1%, core material/wall ration ratio of 1:2, re-condensation pH of 4.67, and curing time of 1 h. The prepared microcapsules ofS. lituranucleopolyhedrovirus exhibited a good external appearance and spherical shapes with an average particle size of 13 μm, an embedding rate of 62.53%, and a drug loading of 43.87%. The virulence test showed that the microencapsulated virus lost by 2.21 times of its initial activity than the untreated virus. After being treated with field exposure, the gelatin/CMC shell of the microcapsule can better protect the virus in the wild environment.ConclusionMicroencapsulation improves the tolerance ofS. lituranuclear polyhedrosis virus to ultraviolet radiation. These results will provide ideas for the research of stable and efficient baculovirus preparations and further promote the application and promotion of environmental friendly biological pesticides.
Correlation of primary tumor metabolic parameters with clinical, histopathological and molecular characteristics in breast cancer patients at pre-operative staging FDG-PET/CT study
Authors: AbdElaal Asmaa A. , Zaher Ahmed M. , Abdelgawad Marwa I. , Mekkawy Mohamed A. , Eloteify Lamiaa M. 
Published: July 2021

Abstract
Background
The aim of this prospective study was to evaluate the correlation of primary tumor metabolic activity parameters; maximum standardized uptake value (SUVmax) and tumor SUVmax/liver average SUV ratio (TLR) with clinical, histopathological and molecular characteristics of initial staging breast cancer (BC) patients using 18F-fluorodeoxyglucose (FDG) positron emission tomography / computerized tomography (PET/CT) scan.

Results
Forty female patients with newly diagnosed BC were enrolled in our study, age ranging from 31-78 years (mean 50.5 +/- SD11.7).
All the primary tumors were detected with mean SUVmax 10.8(+/-SD 7.9). The mean /median SUVmax values of primary tumor was higher in premenopausal , stage III and IV, Estrogen Receptors negative( ER-), Progesterone Receptors negative(PR-), Human epidermal growth factor receptor 2 positive ( Her2neu+) patients, high nuclear grade (GIII), triple negative molecular subgroup (TN) and positive axillary lymph node (ALNs) metastasis,(P= 0.003, 0.017, 0.113, 0.089 0.01 ,0.002 , 0.007 and 0.016 respectively).
The mean/median TLR values was higher in premenopausal ,Her2neu+, GIII, TN molecular subtype patients, stage III and IV and in patients with positive ALNs , ER- and PR - patients (P= 0.002, 0.0476 , 0.005 , 0.018 , 0.039 and 0.022, 0.095 and 0.129 respectively).
SUVmax of the primary lesion and TLR were moderately negatively correlated with the age of the patients (P= 0.005 and 0.008 respectively), also they were moderately positively correlated with the size of the primary tumor (P= 0.019 and 0.036 respectively). TLR was predictive of nodal involvement AUC= 0.612 (95% CI: 0.431-792). The overall sensitivity and specificity of PET/CT for axillary staging was 100 % and 60 %, respectively (P= 0.006).

Conclusion
The SUVmax of the primary tumor and TLR values had similar significant associations with different prognostic factors in BC but only TLR can predict nodal involvement.
Lipid droplets form a network interconnected by the endoplasmic reticulum through which their proteins equilibrate
Authors: Cottier Stéphanie , Schneiter Roger 
Published: July 2021

ABSTRACT
Lipid droplets (LDs) are globular intracellular structures dedicated to the storage of neutral lipids. They are closely associated with the endoplasmic reticulum (ER) and are delineated by a monolayer of phospholipids that is continuous with the cytoplasmic leaflet of the ER membrane. LDs contain a specific set of proteins, but how these proteins are targeted to the LD surface is not fully understood. Here, we devised a yeast mating-based microscopic readout to monitor the transfer of LD proteins upon zygote formation. The results of this analysis indicate that ER fusion between mating partners is required for transfer of LD proteins and that this transfer is continuous, bidirectional and affects most LDs simultaneously. These observations suggest that LDs do not fuse upon mating of yeast cells, but that they form a network that is interconnected through the ER membrane. Consistent with this, ER-localized LD proteins rapidly move onto LDs of a mating partner and this protein transfer is affected by seipin, a protein important for proper LD biogenesis and the functional connection of LDs with the ER membrane.
Tannic Acid Coated Carbon Nanotube Incorporated Polyamide Reverse Osmosis Membrane with High Separation Performance, Fouling Resistance, and Antibacterial Property
Authors: Zhao Afang , Li Qiang , Zhang Na , Deng Huining , Zhao Li , Xu Shicai , Zhang Junye , Baqiah Hussein 
Published: July 2021

Abstract
A polyamide-based nanocomposite reverse osmosis membrane was fabricated by introducing tannic acid coated carbon nanotubes (CNTs) into an oil-phase solution of trimesoyl chloride using an interfacial polymerization approach. The obtained membrane exhibits high permeate flux (67.6 L/m2h), salt rejection (99.4%), fouling resistance, antibacterial and anti-adhesion properties. After silver nanoparticles were embedded into the CNT pore channels, the permeate flux (73.1 L/m2h) and antibacterial property were further improved.
One-step Hydrothermal Synthesis of Unsupported Nickel Phosphide Catalyst for Direct Dehydrogenative Conversion of Methane to Hydrocarbons
Authors: Dipu Arnoldus Lambertus , Yamanaka Ichiro 
Published: July 2021

Abstract
Unsupported Ni2P catalyst synthesized by the hydrothermal method was studied for the direct dehydrogenative conversion of methane to hydrocarbons. The unsupported Ni2P catalyst showed smaller crystallite size and porous surface structure due to the absence of calcination and reduction at higher temperatures and exhibited better catalytic activity at 1173 K. It has been found that the simple hydrothermal method was effective for the synthesis of active unsupported Ni2P catalyst.
Factors Associated with National Health Insurance Coverage in Indonesia
Authors: Sukartini Tintin , Arifin Hidayat , Kurniawati Yulia , Pradipta Rifky Octavia , Nursalam Nursalam , Acob Joel Rey Ugsang 
Published: July 2021

Background: The National Health Insurance (NHI) program is the Indonesian government's national health program. However, health insurance coverage has not been maximized. This study aims to analyze the factors associated with health insurance coverage in Indonesia. Methods: Cross-sectional data were obtained from the Indonesian Demographic and Health Survey 2017. A total of 39,580 respondents were selected using two-stage stratified cluster sampling. The data come from the DHS Questionnaire Phase 7. The variables include age, education level, wealth quintiles, residence, the number of children who are alive, marital status, current employment status, earnings, and health insurance status. The data were analyzed using chi-squared and binary logistic analyses. Results: The prevalence of health insurance coverage in the Indonesian population is 62.3%. Respondent age [AOR=0.875; 95% CI=0.763-0.967], education level [AOR=0.437; 95% CI=0.410-0.466], wealth quintile [AOR=0.762; 95% CI=0.713-0.815], residence [AOR=0.762; 95% CI=0.713-0.815], marital status [AOR=0.718; 95% CI=0.625-0.825] and earnings [AOR=1.245; 95% CI=1.177-1.316] are related to health insurance coverage. However, the number of children who are alive and respondents who were currently working were not significantly related to health insurance coverage in Indonesia. Conclusion: The government needs to pay attention to the characteristics and demographic conditions of the Indonesian population to be able to achieve maximum health insurance coverage. Maximum coverage through the provision of appropriate information should be promoted.
Case Report: Mycotic common carotid artery pseudoaneurysm in a child. A case report.
Authors: Imtinene Ben Mrad , Miri Rim , Melek Ben Mrad , Aloui Wafa , Mleyhi Sobhi , Ben Aba Neila , Ihsen Zairi , Kalfat Tawfik , Denguir Raouf 
Published: July 2021

Extracranial carotid artery aneurysms in children are extremely rare, nevertheless associated with a great potential of thromboembolic episodes and rupture especially those with mycotic origin. The surgical treatment is very challenging, and there is still a controversy concerning revascularisation after the resection of the aneurysm. In this manuscript, we report the observation of an 8-year-old boy with the medical history of Leukemia who is admitted urgently for a mycotic right common carotid artery aneurysm, occurring after a chemoport infection who was operated on in our cardiovascular surgery department with surgical resection and ligation. It is the second report in the pediatric literature of a mycotic pseudoaneurysm situated in the common carotid artery, but the first documented by medical imagery. Through this case, we highlight that ligation of the infected carotid artery can be a safe and efficient alternative especially in Children.
Transformation of Entrepreneurial Activity in the Field of Recreation and Tourism in the Conditions of Digitalization
Authors: Baranova A. , Vorobey E. 
Published: July 2021

After the advent of the Internet, travel planning has become a visual process. Potential tourists book hotels, studying their interior in advance; familiarize themselves with places of recreation and infrastructure of the receiving deprivation, without leaving the house.; comparing prices; study feedback from visitors, etc. The modern tourism business is forced to increasingly use information and communication tools in competition for the client. At present, it is not enough for entrepreneurs to create tourist and recreational infrastructure facilities, it is important to form unforgettable positive emotions, atmosphere and demonstrate this not only in the traditional format, but also with the use of digital technologies. Based on a study of publications, it was revealed that Russian economists consider entrepreneurship in the field of recreation and tourism not just as a risky and profitable activity, but as an innovative one. However, the authors describe mainly economic, political, social and natural risks, leaving out psychophysiological phenomena of stress in both entrepreneurs and consumers of services, which are currently aggravated.
The purpose of the article is to substantiate the role of a modern entrepreneur in the field of recreation and tourism in the conditions of digitalization and give recommendations that contribute to the further development of entrepreneurial activity in the conditions of digitalization.
Polacy u progu niepodległości
Authors: Gąsowski Tomasz 
Published: July 2021

Poles on the Brink of Independence
Due to the final fall of the Polish-Lithuanian Commonwealth, its inhabitants were pushed for 123 years into three completely different and essentially hostile state organisms. In such diverse conditions, a few succeeding generations experienced deep and multilateral civilizational transformations occurring in the 19th century and in the version typical for this part of Europe. In other words, modernity formed here bygone inhabitants and citizens of the Republic in various ways. It was important for further existence of the Polishness and nationality without the state. In this context, the key question arises: who of them, successors of the First Republic tradition, in the time of the Polish state revival, felt still Polish, ready for the construction and defence of the state? In other words, what social capital had the reviving Polish state – the Second Polish Republic – at its disposal in the time of its beginnings? Based on source materials, and primarily on data from the last population censuses and their statistical studies before the First World War, the author tried to estimate the potential number of Poles on the brink of independence. The analysis was connected with an important assumption that primarily these people would be both the main beneficiaries of this radically changed statehood and persons ready to co-shape it actively. The obtained results fit into few similar estimations made until now, constituting material for further reflections.
Wound hygiene survey: awareness, implementation, barriers and outcomes
Authors: Murphy Chris , Atkin Leanne , Hurlow Jenny , Swanson Terry , de Ceniga Melina Vega 
Published: July 2021

Objective: In light of the COVID-19 pandemic, which has resulted in changes to caseload management, access to training and education, and other additional pressures, a survey was developed to understand current awareness and implementation of the wound hygiene concept into practice one year on from its dissemination. Barriers to implementation and outcomes were also surveyed. Method: The 26-question survey, a mixture of multiple choice and free-text, was developed by the Journal of Wound Care projects team, in consultation with ConvaTec, and distributed globally via email and online; the survey was open for just over 12 weeks. Due to the exploratory nature of the research, non-probability sampling was used. The authors reviewed the outputs of the survey to draw conclusions from the data, with the support of a medical writer. Results: There were 1478 respondents who agreed to the use of their anonymised aggregated data. Nearly 90% were from the US or UK, and the majority worked in wound care specialist roles, equally distributed between community and acute care settings; 66.6% had been in wound care for more than 8 years. The respondents work across the spectrum of wound types. More than half (57.4%) had heard of the concept of wound hygiene, of whom 75.3% have implemented it; 78.7% answered that they ‘always’ apply wound hygiene and 20.8% ‘sometimes’ do so. The top three barriers to adoption were confidence (39.0%), the desire for more research (25.7%) and competence (24.8%). Overall, following implementation of wound hygiene, 80.3% reported that their patients' healing rates had improved. Conclusion: Respondents strongly agreed that implementing wound hygiene is a successful approach for biofilm management and a critical component for improving wound healing rates in hard-to-heal wounds. However, the barriers to its uptake and implementation demonstrate that comprehensive education and training, institutional support for policy and protocol changes, and more clinical research are needed to support wound hygiene.
3D-printed titanium implant combined with interleukin 4 regulates ordered macrophage polarization to promote bone regeneration and angiogenesis
Authors: Zhao Da-Wang , Ren Bing , Wang Hong-Wei , Zhang Xiao , Yu Ming-Zhi , Cheng Lei , Sang Yuan-Hua , Cao Shuai-Shuai , Thieringer Florian M. , Zhang Dong , Wan Yi , Liu Chao 
Published: July 2021

Aims The use of 3D-printed titanium implant (DT) can effectively guide bone regeneration. DT triggers a continuous host immune reaction, including macrophage type 1 polarization, that resists osseointegration. Interleukin 4 (IL4) is a specific cytokine modulating osteogenic capability that switches macrophage polarization type 1 to type 2, and this switch favours bone regeneration. Methods IL4 at concentrations of 0, 30, and 100 ng/ml was used at day 3 to create a biomimetic environment for bone marrow mesenchymal stromal cell (BMMSC) osteogenesis and macrophage polarization on the DT. The osteogenic and immune responses of BMMSCs and macrophages were evaluated respectively. Results DT plus 30 ng/ml of IL4 (DT + 30 IL4) from day 3 to day 7 significantly (p < 0.01) enhanced macrophage type 2 polarization and BMMSC osteogenesis compared with the other groups. Local injection of IL4 enhanced new bone formation surrounding the DT. Conclusion DT + 30 IL4 may switch macrophage polarization at the appropriate timepoints to promote bone regeneration. Cite this article: Bone Joint Res 2021;10(7):411–424.