bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sense of coherence and perception of self-influence on the disease course among patients with schizophrenia including quality of life – pilot studies
Authors: Biczak Joanna , Iniewicz Grzegorz , Cichocki Łukasz 
Published: November 2021

Cel pracyAktualne badania kliniczne wskazują na wiele czynników mogących mieć wpływ zarówno pozytywny, jak i negatywny na występowanie kolejnych epizodów choroby u pacjentów z rozpoznaniem schizofrenii. Głównym celem tej pracy była wstępna analiza związku pomiędzy poczuciem koherencji i wpływu na przebieg choroby a jakością życia uwarunkowaną aktualnym stanem zdrowia osób chorych na schizofrenię.MetodaBadanie przeprowadzone zostało wśród 50 chorych, u których zdiagnozowano schizofrenię zgodnie z kryteriami ICD-10, i którzy na przestrzeni 2 lat od ostatniej hospitalizacji doświadczyli/ bądź nie kolejnego epizodu schizofrenii. W celu dokonania oceny aktualnego poczucia koherencji, wpływu na przebieg choroby i jakości życia uczestnicy poproszeni zostali o wypełnienie: Kwestionariusza Orientacji Życiowych (SOC-29), Krótkiej Skali Poczucia Wpływu na Przebieg Choroby – Wersja dla Schizofrenii i Kwestionariusza Poczucia Jakości Życia.WynikiAnaliza statystyczna wykazała brak istotnych różnic pod względem poczucia koherencji, wpływu na przebieg choroby, czy jakości życia pomiędzy osobami z nawrotem i pozostającymi w remisji. Równocześnie w obu porównywanych grupach zaobserwowano występowanie związku pomiędzy poczuciem koherencji i jakością życia. W grupie osób z nawrotem choroby odnotowano także korelację jakości życia w sferze metafizycznej (duchowej) z poczuciem wpływu na przebieg choroby.WnioskiPrzeprowadzone badanie pilotażowe nasuwa przypuszczenie, że niezależnie od aktualnego stanu zdrowia, u pacjentów z rozpoznaniem schizofrenii to poczucie koherencji w sferze zaradności i sensowności może być ściśle powiązane z psychofizyczną, psychospołeczną i podmiotową sferą jakości ich życia.
Changes in self-reported emotional and behavioral problems of Polish adolescents in 2000 and 2013
Authors: Konowałek Łukasz , Srebnicki Tomasz 
Published: November 2021

Cel pracyOpisujemy zmiany w samoopisie problemów emocjonalnych i behawioralnych polskich nastolatków na przestrzeni 13 lat. Chociaż już wcześniej opisywaliśmy podobne zmiany w populacji 16 latków, do tej pory nie mieliśmy dostępu do danych dla szerszego przedziału wiekowego.MetodaDo oceny nasilenia problemów emocjonalnych i behawioralnych posłużyliśmy się kwestionariuszem Youth Self Report (YSR). Porównaliśmy mediany wyników oraz przeprowadziliśmy analizy regresji przy uwzględnieniu czynników takich jak wiek i płeć. Przeprowadziliśmy analizę regresji logistycznej z użyciem wyników z obszaru klinicznego.WynikiMediany wyników większości skal były wyższe po 13 latach, chociaż różnice nie były duże. Uzyskaliśmy efekt moderacji płci i wieku. Wyniki z obszaru klinicznego na skalach problemów z uwagą oraz problemów z myśleniem były półtora raza częstsze w grupe badanej z roku 2013.WnioskiNie stwierdzamy istotnych różnic w samoopisie problemów emocjonalnych i behawioralnych polskich nastolatków w latach 2000-2013. Zaobserwowaliśmy inne sposoby radzenia sobie z presją psychiczną u chłopców i dziewcząt: chłopcy raportowali więcej problemów z niedostosowaniem oraz zachowań eksternalizacyjnych, a dziewczęta raportowały więcej problemów na wszystkich skalach.
Optimizing over the Closure of Rank Inequalities with a Small Right-Hand Side for the Maximum Stable Set Problem via Bilevel Programming
Authors: Coniglio Stefano , Gualandi Stefano 
Published: November 2021

In the context of the maximum stable set problem, rank inequalities impose that the cardinality of any set of vertices contained in a stable set be, at most, as large as the stability number of the subgraph induced by such a set. Rank inequalities are very general, as they subsume many classical inequalities such as clique, hole, antihole, web, and antiweb inequalities. In spite of their generality, the exact separation of rank inequalities has never been addressed without the introduction of topological restrictions on the induced subgraph and the tightness of their closure has never been investigated systematically. In this work, we propose a methodology for optimizing over the closure of all rank inequalities with a right-hand side no larger than a small constant without imposing any restrictions on the topology of the induced subgraph. Our method relies on the exact separation of a relaxation of rank inequalities, which we call relaxed k-rank inequalities, whose closure is as tight. We investigate the corresponding separation problem, a bilevel programming problem asking for a subgraph of maximum weight with a bound on its stability number, whose study could be of independent interest. We first prove that the problem is [Formula: see text]-hard and provide some insights on its polyhedral structure. We then propose two exact methods for its solution: a branch-and-cut algorithm (which relies on a family of faced-defining inequalities which we introduce in this paper) and a purely combinatorial branch-and-bound algorithm. Our computational results show that the closure of rank inequalities with a right-hand side no larger than a small constant can yield a bound that is stronger, in some cases, than Lovász’s Theta function, and substantially stronger than bounds obtained with standard inequalities that are valid for the stable set problem, including odd-cycle inequalities and wheel inequalities. Summary of Contribution: This paper proposes two original methods for solving a challenging cut-separation problem (of bilevel type) for a large class of inequalities valid for one of the key operations research problems, namely, the max stable set problem. An extensive set of experimental results validates the proposed methods. All the source code and data sets are available online on GitHub.
Improving timeliness in the neglected tropical diseases preventive chemotherapy donation supply chain through information sharing: A retrospective empirical analysis
Authors: Kasparis Elena , Huang Yufei , Lin William , Vasilakis Christos 
Published: November 2021

Background
Billions of doses of medicines are donated for mass drug administrations in support of the World Health Organization’s “Roadmap to Implementation,” which aims to control, eliminate, and eradicate Neglected Tropical Diseases (NTDs). The supply chain to deliver these medicines is complex, with fragmented data systems and limited visibility on performance. This study empirically evaluates the impact of an online supply chain performance measurement system, “NTDeliver,” providing understanding of the value of information sharing towards the success of global health programs.

Methods
Retrospective secondary data were extracted from NTDeliver, which included 1,484 shipments for four critical medicines ordered by over 100 countries between February 28, 2006 and December 31, 2018. We applied statistical regression models to analyze the impact on key performance metrics, comparing data before and after the system was implemented.

Findings
The results suggest information sharing has a positive association with improvement for two key performance indicators: purchase order timeliness (β = 0.941, p = 0.003) and—most importantly—delivery timeliness (β = 0.828, p = 0.027). There is a positive association with improvement for three variables when the data are publicly shared: shipment timeliness (β = 2.57, p = 0.001), arrival timeliness (β = 2.88, p = 0.003), and delivery timeliness (β = 2.82, p = 0.011).

Conclusions
Our findings suggest that information sharing between the NTD program partners via the NTDeliver system has a positive association with supply chain performance improvements, especially when data are shared publicly. Given the large volume of medicine and the significant number of people requiring these medicines, information sharing has the potential to provide improvements to global health programs affecting the health of tens to hundreds of millions of people.
Change in treatment burden among people with multimorbidity: Protocol of a follow up survey and development of efficient measurement tools for primary care
Authors: Hounkpatin Hilda O. , Roderick Paul , Morris James E. , Harris Scott , Watson Forbes , Dambha-Miller Hajira , Roberts Helen , Walsh Bronagh , Smith Dianna , Fraser Simon D. S. ,   on behalf of the ARC Wessex Treatment Burden Group
Published: November 2021

BackgroundTreatment burden is the effort required of patients to look after their health and the impact this has on their functioning and wellbeing. It is likely treatment burden changes over time as circumstances change for patients and health services. However, there are a lack of population-level studies of treatment burden change and factors associated with this change over time. Furthermore, there are currently no practical screening tools for treatment burden in time-pressured clinical settings or at population level.Methods and analysisThis is a three-year follow-up of a cross-sectional survey of 723 people with multimorbidity (defined as three or more long-term conditions; LTCs) registered at GP practices in in Dorset, England. The survey will repeat collection of information on treatment burden (using the 10-item Multimorbidity Treatment Burden Questionnaire (MTBQ) and a novel single-item screening tool), sociodemographics, medications, LTCs, health literacy and financial resource, as at baseline. Descriptive statistics will be used to compare change in treatment burden since the baseline survey in 2019 and associations of treatment burden change will be assessed using regression methods. Diagnostic test accuracy metrics will be used to evaluate the single-item treatment burden screening tool using the MTBQ as the gold-standard. Routine primary care data (including demographics, medications, LTCs, and healthcare usage data) will be extracted from medical records for consenting participants. A forward-stepwise, likelihood-ratio logistic regression model building approach will be employed in order to assess the utility of routine data metrics in quantifying treatment burden in comparison to self-reported treatment burden using the MTBQ.ImpactTo the authors’ knowledge, this will be the first study investigating longitudinal aspects of treatment burden. Findings will improve understanding of the extent to which treatment burden changes over time for people with multimorbidity and factors contributing to this change, as well as allowing better identification of people at risk of high treatment burden.
Using allocative efficiency analysis to inform health benefits package design for progressing towards Universal Health Coverage: Proof-of-concept studies in countries seeking decision support
Authors: Fraser-Hurt Nicole , Hou Xiaohui , Wilkinson Thomas , Duran Denizhan , Abou Jaoude Gerard J. , Skordis Jolene , Chukwuma Adanna , Lao Pena Christine , Tshivuila Matala Opope O. , Gorgens Marelize , Wilson David P. 
Published: November 2021

Background
Countries are increasingly defining health benefits packages (HBPs) as a way of progressing towards Universal Health Coverage (UHC). Resources for health are commonly constrained, so it is imperative to allocate funds as efficiently as possible. We conducted allocative efficiency analyses using the Health Interventions Prioritization tool (HIPtool) to estimate the cost and impact of potential HBPs in three countries. These analyses explore the usefulness of allocative efficiency analysis and HIPtool in particular, in contributing to priority setting discussions.

Methods and findings
HIPtool is an open-access and open-source allocative efficiency modelling tool. It is preloaded with publicly available data, including data on the 218 cost-effective interventions comprising the Essential UHC package identified in the 3rd Edition of Disease Control Priorities, and global burden of disease data from the Institute for Health Metrics and Evaluation. For these analyses, the data were adapted to the health systems of Armenia, Côte d’Ivoire and Zimbabwe. Local data replaced global data where possible. Optimized resource allocations were then estimated using the optimization algorithm. In Armenia, optimized spending on UHC interventions could avert 26% more disability-adjusted life years (DALYs), but even highly cost-effective interventions are not funded without an increase in the current health budget. In Côte d’Ivoire, surgical interventions, maternal and child health and health promotion interventions are scaled up under optimized spending with an estimated 22% increase in DALYs averted–mostly at the primary care level. In Zimbabwe, the estimated gain was even higher at 49% of additional DALYs averted through optimized spending.

Conclusions
HIPtool applications can assist discussions around spending prioritization, HBP design and primary health care transformation. The analyses provided actionable policy recommendations regarding spending allocations across specific delivery platforms, disease programs and interventions. Resource constraints exacerbated by the COVID-19 pandemic increase the need for formal planning of resource allocation to maximize health benefits.
Age-related changes of color visual acuity in normal eyes
Authors: Yokoyama Sho , Tanaka Yoshiki , Kojima Takashi , Horai Rie , Kato Yukihito , Nakamura Hideki , Sato Hiroyuki , Mitamura Mari , Tanaka Kiyoshi , Ichikawa Kazuo 
Published: November 2021

Purpose
To evaluate the age-related change in color visual acuity (CVA) in normal eyes.

Methods
In total, 162 normal eyes (162 subjects, women: 52, men: 110, age range: 15–68 years) with best-corrected visual acuity (BCVA) ≥20/13 were enrolled. Fifteen colors from the New Color Test (chroma 6) were applied to Landolt “C” rings, white point D65 was applied as background, and a luminance of 30 cd/m2 was set for both the rings and the background. These rings were used to measure the chromatic spatial discrimination acuity as the CVA value, while changing the stimulus size. Correlations of the CVA value of each color and age were evaluated. Mean CVA values of all 15 colors (logarithm of the minimum angle of resolution) were compared between age groups in 10-year increments.

Results
Nine CVA values (red, yellow-red, red-yellow, green, blue-green, green-blue, purple, red-purple, and purple-red) were negatively correlated with age (all p<0.05); the remaining six (yellow, green-yellow, yellow-green, blue, purple-blue, and blue-purple), as well as BCVA were not. The age groups with the best to worst mean CVA values of 15 colors were as follows: 20–29 (mean ± standard deviation, 0.303 ± 0.113), 30–39 (0.324 ± 0.096), 10–19 (0.333 ± 0.022), 50–59 (0.335 ± 0.078), 40–49 (0.339 ± 0.096), and 60–69 (0.379 ± 0.125) years. There were statistically significant differences between mean CVA values of the following groups: 20–29 and 40–49 years; 20–29 and 60–69 years; 30–39 and 60–69 years (all p<0.01).

Conclusions
The CVA values related to the medium/long-wavelength-sensitive cones were more susceptible to aging than those related to the short-wavelength-sensitive cones. This differed from previous reports, and may be related to the difference in the range of foveal cone function evaluated with each examination.
Transparency in peer review: Exploring the content and tone of reviewers’ confidential comments to editors
Authors: O’Brien Bridget C. , Artino Anthony R. , Costello Joseph A. , Driessen Erik , Maggio Lauren A. 
Published: November 2021

Purpose
Recent calls to improve transparency in peer review have prompted examination of many aspects of the peer-review process. Peer-review systems often allow confidential comments to editors that could reduce transparency to authors, yet this option has escaped scrutiny. Our study explores 1) how reviewers use the confidential comments section and 2) alignment between comments to the editor and comments to authors with respect to content and tone.

Methods
Our dataset included 358 reviews of 168 manuscripts submitted between January 1, 2019 and August 24, 2020 to a health professions education journal with a single blind review process. We first identified reviews containing comments to the editor. Then, for the reviews with comments, we used procedures consistent with conventional and directed qualitative content analysis to develop a coding scheme and code comments for content, tone, and section of the manuscript. For reviews in which the reviewer recommended “reject,” we coded for alignment between reviewers’ comments to the editor and to authors. We report descriptive statistics.

Results
49% of reviews contained comments to the editor (n = 176). Most of these comments summarized the reviewers’ impression of the article (85%), which included explicit reference to their recommended decision (44%) and suitability for the journal (10%). The majority of comments addressed argument quality (56%) or research design/methods/data (51%). The tone of comments tended to be critical (40%) or constructive (34%). For the 86 reviews recommending “reject,” the majority of comments to the editor contained content that also appeared in comments to the authors (80%); additional content tended to be irrelevant to the manuscript. Tone frequently aligned (91%).

Conclusion
Findings indicate variability in how reviewers use the confidential comments to editor section in online peer-review systems, though generally the way they use them suggests integrity and transparency to authors.
‘I Have Made a Highway of Biainili’:
Authors: Çifçi Ali , Gökce Bilcan 
Published: November 2021

Abstract
After emerging in the Lake Van Basin of Turkey, the Urartian kingdom expanded its territory across Eastern Anatolia, Northwestern Iran, and Armenia between the late 9th and early 7th century BC. The high altitude of these regions and the climatic conditions, especially long and harsh winters with heavy snowfall, likely forced the Urartian monarchy to establish a reliable network of communication: new roads and new settlements along these roads were established between the capital city Tušpa and other parts of its territory. This study presents a reassessment of the archaeological and textual evidence on Urartian routes used for military campaigns, settlements located along these routes, ancient road remains and means of transportation.
Contramodules over pro-perfect topological rings
Authors: Positselski Leonid 
Published: November 2021

Abstract
For four wide classes of topological rings

R

\mathfrak{R}

, we show that all flat left

R

\mathfrak{R}

-contramodules have projective covers if and only if all flat left

R

\mathfrak{R}

-contramodules are projective if and only if all left

R

\mathfrak{R}

-contramodules have projective covers if and only if all descending chains of cyclic discrete right

R

\mathfrak{R}

-modules terminate if and only if all the discrete quotient rings of

R

\mathfrak{R}

are left perfect.
Three classes of topological rings for which this holds are the complete, separated topological associative rings with a base of neighborhoods of zero formed by open two-sided ideals such that either the ring is commutative, or it has a countable base of neighborhoods of zero, or it has only a finite number of semisimple discrete quotient rings.
The fourth class consists of all the topological rings with a base of neighborhoods of zero formed by open right ideals which have a closed two-sided ideal with certain properties such that the quotient ring is a topological product of rings from the previous three classes.
The key technique on which the proofs are based is the contramodule Nakayama lemma for topologically T-nilpotent ideals.
Don’t Let the COVID-19 Crisis Go to Waste: Breaking Through the Status Quo & Flattening the Opioid Epidemic Curve
Authors: Bose Feler , Menzies Percy , Rottnek Fred 
Published: November 2021

Abstract
The objective of the paper is to understand the impact of the COVID-19 focusing event that resulted in a distinctive response by the Federal government. The paper focuses on the rapid deregulation that occurred in the opioid use disorder treatments. We frame the narrative using primarily the economic literature on deregulation during a crisis. The temporary deregulation has significantly increased access to treatment and medications and allows for the discovering of a different equilibrium. We also suggest other deregulations that need to be considered. In this paper, we suggest that the provisional deregulations should be made permanent to improve the outcome of the patients who abuse opioids.
Wolfhart Pannenberg’s Semiotic Doctrine of the Church: A Peircean Corrective
Authors: Hollingsworth Andrew 
Published: November 2021

Abstract
This paper aims to explore and critique Wolfhart Pannenberg’s use of semiotic concepts in his understanding and explanation of the church. He defines the church as “the fellowship of individual believers,” and a “sign of the future fellowship of humanity under God’s reign,” i. e. the future Kingdom of God. As he continues to articulate his doctrine of the church, Pannenberg employs semiotic concepts to articulate this notion of the church as a sign of the Kingdom of God. In this paper, I aim to explore Pannenberg’s use of semiotic concepts as they concern his understanding of the church and provide critique and a new way forward of understanding the church as a sign of the Kingdom of God. Though Pannenberg is right to employ semiotic concepts and terminology to expound upon and clarify this concept, he is wrong in the semiotic model of the sign and approach he chooses to employ. In what follows, I first summarize and explicate Pannenberg’s semiotic understanding of the church, and then I provide a critique and corrective of his semiotic preferences with the semiotic work of American philosopher Charles Sanders Peirce.
Anthropologie der Unsterblichkeit
Authors: Streubel Thorsten 
Published: November 2021

Zusammenfassung
Ich möchte in diesem Artikel aufzeigen, dass ein Leben oder zumindest eine Fortexistenz des Subjekts nach dem physischen Tod aus anthropologischer Sicht durchaus nicht ausgeschlossen, die Fortexistenz einer Person durch die (vermeintliche) Übertragung ihres Geistes auf eine Festplatte (mind-uploading bzw. whole brain emulation) dagegen aus prinzipiellen Gründen unmöglich ist. Beide Thesen lassen sich durch eine Reflexion auf die humane Verfassung begründen.
The Relationship Between Economic Structure and Political Violence in Latin America (1990–2019)
Authors: Balestra Anna 
Published: November 2021

Abstract
This paper provides evidence about the relationship between economic structure and political violence in Latin American countries in the period 1990–2019. The empirical analysis suggests that manufacturing activities are negatively associated with the number of terroristic attacks. On the contrary it exists a positive relationship between mining activities and political violence. A further analysis suggests that the relative size of manufacturing with respect to mining sector is negatively associated to terroristic attacks occurrence. Such relationship becomes stronger when it is associated to high levels of trade openness.