bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors, diagnosis, and treatment of peri‐implantitis: A cross‐cultural comparison of U.S. and European periodontists’ considerations
Authors: Polymeri Angeliki , Loos Bruno G. , Aronovich Sharon , Steigmann Larissa , Inglehart Marita R. 
Published: August 2021

AbstractBackgroundPeri‐implantitis (PI) is a growing concern in the dental community worldwide. The study aimed to compare U.S. versus European periodontists’ considerations of risk factors, diagnostic criteria, and management of PI.MethodsA total of 393 periodontists from the United States and 100 periodontists from Europe (Germany, Greece, Netherlands) responded to anonymous surveys electronically or by mail.ResultsCompared to U.S. periodontists, European respondents were younger, more likely to be female and placed fewer implants per month (9.12 vs 13.90; P = 0.003). Poor oral hygiene, history of periodontitis, and smoking were considered as very important risk factors by both groups (rated > 4 on 5‐point scale). European periodontists rated poor oral hygiene (4.64 vs 4.45; P = 0.005) and history of periodontitis (4.36 vs 4.10; P = 0.006) as more important and implant surface (2.91 vs 3.18; P = 0.023), occlusion (2.80 vs 3.75; P < 0.001) and presence of keratinized tissue (3.27 vs 3.77; P < 0.001) as less important than did U.S. periodontists. Both groups rated clinical probing, radiographic bone loss, and presence of bleeding and suppuration as rather important diagnostic criteria. They rated implant exposure/mucosal recession as relatively less important with U.S. periodontists giving higher importance ratings than European periodontists (3.99 vs 3.54; P = 0.001). Both groups nearly always used patient education, plaque control and mechanical debridement when treating PI. U.S. periodontists were more likely to use antibiotics (3.88 vs 3.07; P < 0.001), lasers (2.11 vs 1.68; P = 0.005), allograft (3.39 vs 2.14; P < 0.001) and regenerative approaches (3.57 vs 2.56; P < 0.001), but less likely to use resective surgery (3.09 vs 3.53; P < 0.001) than European periodontists.ConclusionsU.S. and European periodontists’ considerations concerning risk factors, diagnosis and management of PI were evidence‐based. Identified differences between the two groups can inform future educational efforts.
Counterfactual approach on the effect of metabolic syndrome on tooth loss: A population‐based study
Authors: Souza Marina Leite , Nascimento Gustavo G. , González‐Chica David Alejandro , Peres Karen Glazer , Peres Marco Aurélio 
Published: August 2021

AbstractBackgroundThis study aimed to investigate the effect of metabolic syndrome (MetS) on tooth loss in adults from a population‐based sample.MethodsCross‐sectional analysis based on data from a cohort study (2009 to 2014) with adults from Southern Brazil. MetS (exposure), lack of functional dentition and number of lost teeth (outcomes) were assessed using self‐reported, laboratory and clinical data. Possible confounders included sex, age, family income, education level, smoking status, and sugar consumption. The effect of MetS on the outcomes was estimated using conventional logistic or negative binomial regression models. Marginal structural modeling (MSM) with stabilized weights (a counterfactual analytical method) was also used to enhance group comparability and estimate causal effects.ResultsA total of 1,283 participants had available information for the outcomes. Individuals with MetS were more likely to experience a lack of functional dentition than those without MetS (odds ratio [OR] from logistic regression, 1.7; 95% CI, 1.0 to 2.9; OR from MSM, 3.2; 95% CI, 2.3 to 4.6). Moreover, the number of teeth lost was 20% higher in participants with MetS compared with those without MetS in conventional analysis (mean ratio [MR], 1.2; 95% CI, 1.1 to 1.3). The MR increased to 1.7 (95% CI, 1.5 to 2.0) when using MSM.ConclusionOur findings provide evidence on the effect of MetS on tooth loss.
The “oral” history of COVID‐19: Primary infection, salivary transmission, and post‐acute implications
Authors: Marchesan Julie Teresa , Warner Blake M. , Byrd Kevin Matthew 
Published: August 2021

AbstractSevere acute respiratorysyndrome coronavirus 2 (SARS‐CoV‐2), the causative agent of COVID‐19, has led to more than 3.25 million recorded deaths worldwide as of May 2021. COVID‐19 is known to be clinically heterogeneous, and whether the reported oral signs and symptoms in COVID‐19 are related to the direct infection of oral tissues has remained unknown. Here, we review and summarize the evidence for the primary infection of the glands, oral mucosae, and saliva by SARS‐CoV‐2. Not only were the entry factors for SARS‐CoV‐2 found in all oral tissues, but these were also sites of SARS‐CoV‐2 infection and replication. Furthermore, saliva from asymptomatic individuals contained free virus and SARS‐CoV‐2‐infected oral epithelial cells, both of which were found to transmit the virus. Collectively, these studies support an active role of the oral cavity in the spread and transmission of SARS‐CoV‐2 infection. In addition to maintaining the appropriate use of personal protective equipment and regimens to limit microbial spread via aerosol or droplet generation, the dental community will also be involved in co‐managing COVID‐19 “long haulers”—now termed Post‐Acute COVID‐19 Syndrome. Consequently, we propose that, as SARS‐CoV‐2 continues to spread and as new clinical challenges related to COVID‐19 are documented, oral symptoms should be included in diagnostic and prognostic classifications as well as plans for multidisciplinary care.
Predictors of Intimate Partner Violence Victimization by Multiple Partners Over a Period of 8 Years
Authors: Stein Sara F. , Galano Maria M. , Grogan‐Kaylor Andrew C. , Clark Hannah M. , Ribaudo Julie M. , Graham‐Bermann Sandra A. 
Published: August 2021

AbstractIntimate partner violence (IPV) is a pervasive social issue with broad physical and mental health implications. Although 35%–56% of women report IPV victimization with more than one violent partner, few studies have identified factors that increase the risk of experiencing IPV across multiple partners (i.e., IPV reengagement). In the current study, multilevel modeling was used to examine the roles of trauma exposure, mental health, and sociodemographic factors in the risk for reengagement in a sample of women (N= 120) with IPV victimization. Participants were drawn from a randomized control trial of an intervention for mothers who had experienced IPV. The results revealed that more psychological but less sexual IPV was associated with increased reengagement. Higher degrees of posttraumatic reexperiencing symptoms were associated with less reengagement. Depressive symptoms were also significantly associated with reengagement such that lower levels of positive affect and increased somatic symptoms were associated with increased reengagement. Higher income levels and less housing instability were associated with more reengagement, βrange= −.13–.16. Finally, compared to the control condition, participation in the intervention program was significantly associated with lower levels of reengagement at 8‐year follow‐up, β = −.75,p= .001. These findings suggest that it is not what happened (i.e., experiences of abuse) but rather a woman's posttraumatic experience (i.e., posttraumatic stress and depressive symptoms) that creates risk for reengagement. The findings support the long‐term effectiveness of a brief intervention in reducing reengagement.
Discussing a challenging document focused on land use: The first bibliometric analysis of Laudato Si′
Authors: Mourao Paulo Reis , Martinho Vítor Domingues 
Published: August 2021

AbstractWe live in challenging times on several levels, and in this context the second encyclical, Laudato Si′ (LS), of Pope Francis, published in 2015, has provided a special challenge for academics. As Pope Francis suggested in 2015, societies are challenged to modify the paradigms of life to achieve more sustainable development. LS has quickly become a widely quoted document, often used by academics. This paper is the first bibliometric research about LS aiming to analyze this encyclical and explore several works published about LS between 2015 and 2020. To this end, we studied all documents published in the Web of Science Core Collection (238) and Scopus (222) about the topic Laudato Si in‐depth and analyzed them using bibliometric methods. The results show that there are scientific fields focused on studying LS in particular, namely religious sciences and the fields of sustainability and environment studies. We also observed a small amount of networking among the authors publishing about LS.
Trends and patterns of neurotology drug prescriptions on a nationwide insurance database
Authors: Goshtasbi Khodayar , Abouzari Mehdi , Abiri Arash , Ziai Kasra , Lehrich Brandon M. , Risbud Adwight , Bayginejad Soha , Lin Harrison W. , Djalilian Hamid R. 
Published: August 2021

AbstractObjectiveTo examine neurotologists' 2013 to 2016 Medicare Part‐D data and evaluate commonly prescribed medications, longitudinal changes in prescribing patterns, presumed associated pathologies, and cost distribution across United States.MethodsComprehensive prescription data of Part‐D‐participating neurotologists was quiered from the 2013 to 2016 Medicare Part‐D database. Outcome variables consisted of the 25 most commonly prescribed + refilled medications, cost distribution per medication, presumed associated pathologies, and standardized prescription cost across United States.ResultsOf the 594 available U.S. neurotologists, 336 (57%) were found in the Medicare Part‐D database. In 2016, total prescription costs were $4 483 268 with an averaged $13 343 ± $18 698 per neurotologist. The three most frequently filled drugs were fluticasone propionate, ciprofloxacin, and triamterene‐hydrochlorothiazide. From 2013 to 2016, the greatest change in prescription pattern was observed with azelastine (+188%), montelukast sodium (+104%), mupirocin (+63%), and mometasone (−91%), whereas the greatest change in relative drug cost distribution was seen in ofloxacin, (+695.7%) neomycin‐polymyxin‐hydrocortisone (+262.1%), and mometasone (−83%). Triamterene‐hydrochlorothiazide, prednisone, montelukast, amoxicillin‐clavulanate, azelastine, spironolactone, and mupirocin had statistically significant increases in average number of prescriptions per physician, whereas ofloxacin and mometasone had significant decreases. Medications presumably treating Eustachian tube dysfunction, Meniere's disease, and vestibular migraine had the greatest percent changes across years. Cost distribution of four drugs increased upwards of 100%. Geographic analysis demonstrated that Southern and Midwest regions had higher standardized prescription costs.ConclusionsThis study is the first to analyze neurotologists' trends in prescribing patterns, regional prescription cost distributions, and commonly treated pathologies. This can lead to better standardization of prescribing patterns and cost in the future.
A novel view of computed tomography images similar to the visual field of otologic surgeons
Authors: Kadowaki Yoshinori , Hirano Takashi , Suzuki Masashi 
Published: August 2021

AbstractObjectivesIn preparation for endoscopic sinus surgery (ESS), the most important computed tomography (CT) image for otolaryngologists is the coronal plane image because it has a viewpoint similar to that of the surgical visual field. Contrastingly, otologic surgeons refer to axial and coronal plane images before ear surgery and must imagine the anatomical structure of the temporal bone by reconstructing three‐dimensional (3D) images in their minds. We propose a “surgical position view (SPV) image,” a novel viewpoint of CT images that enables otologic surgeons to see a perspective similar to the surgical visual field.MethodSagittal plane CT images of the temporal bone were created from axial plane images with multi‐planar reconstruction (MPR). Then, the SPV image was obtained by rotating it 90° to the supine position. The entire process can be performed anywhere in the hospital within 1 minute using the electronic medical record computer's image viewer.ResultsSPV images show anatomical structures of the temporal bone, external ear canal, mastoid cavity, sigmoid vein, facial nerve, ossicles, and cochlea, in a similar view to the actual ear surgery. Soft tissue such as cholesteatoma is depicted in the same concentration as the normal CT image.ConclusionThe SPV image enables an otologic surgeon to see the temporal bone CT image from the actual ear surgery viewpoint simply and quickly. It helps to visualize the 3D anatomical structure of the temporal bone and can be useful for ear surgery planning.Level of evidence5
Stimuli‐Responsive Hydrogels Based on Random Copolymers of the Sucrose Methacrylate
Authors: Gouvea Ricardo Santiago de Oliveira , Felisberti Maria Isabel 
Published: August 2021

AbstractPoly(sucrose methacrylate‐co‐acrylic acid), P(SMA‐co‐AA), and poly(sucrose methacrylate‐co‐diethylene glycol methyl ether methacrylate), P(SMA‐co‐EG2MA), are synthesized by free radical polymerization using sucrose dimethacrylate as a crosslinker. The copolymers present one glass transition suggesting a random distribution of the comonomers. The copolymers–water interaction parameter χ is around 0.5, while Mc increases with SMA molar fraction. The kinetics of water swelling show a Fickian behavior for P(SMA‐co‐AA) richer in acrylic acid. The swelling is driven by the ionic character of the P(SMA‐co‐AA), except at pH = 2, and by the hydrophilicity of the SMA for the P(SMA‐co‐EG2MA). The temperature influences the swelling behavior of the P(SMA‐co‐EG2MA) due to the lower critical solution temperature (LCST) behavior. The pH‐ and thermoresponsiveness of the P(SMA‐co‐AA) and P(SMA‐co‐EG2MA) hydrogels are maintained by replacing the sensitive comonomers with SMA up to mass fractions of 85 and 20 wt%, respectively, ≈71 and 17 wt% of sucrose, a product from a renewable resource. The hydrolytic degradation of the hydrogels is more pronounced for copolymers richer in SMA and resulted in sucrose release. Hydrogels present viscoelastic behavior, and the P(SMA‐co‐AA) series is more resistant to compression. The xerogels of the copolymers richer in SMA show a foam‐like morphology with open cells.
Prevalence of Parkinson's Disease: A Community‐Based Study in China
Authors: Qi Shige , Yin Peng , Wang Linhong , Qu Ming , Kan Ge Lin , Zhang Han , Zhang Qingjun , Xiao Yize , Deng Ying , Dong Zhong , Shi Yan , Meng Jun , Chan Piu , Wang Zhihui 
Published: August 2021

AbstractBackgroundChina's socioeconomic and population structures have evolved markedly during the past few decades, and consequently, monitoring the prevalence of Parkinson's disease (PD) is crucial.ObjectiveThis study aimed to investigate the prevalence of PD within Chinese communities, particularly in older people.MethodsA nationwide study of 24,117 participants, aged 60 years or older, was carried out in 2015 using multistage clustered sampling. All participants were initially screened using a nine‐item questionnaire, from which those suspected of having PD were examined by neurologists and a diagnosis was given, according to the 2015 Movement Disorder Society Clinical Diagnostic Criteria.ResultsThe prevalence of PD was 1.37% (95% confidence interval 1.02%–1.73%) in people aged over 60 years. Thus, the estimated total number of people in China with PD could be as high as 3.62 million.ConclusionsAlthough the PD population prevalence percentage did not change significantly, the total number of PD sufferers has increased with the increased population, which poses a significant challenge in a rapidly aging population. © 2021 International Parkinson and Movement Disorder Society
Comparison between normal and reverse orientation of graft in functional and histomorphological outcomes after autologous nerve grafting: An experimental study in the mouse model
Authors: Lee Duk Hee , You Jooyoung , Jung Ji Won , Park Jong Woong , Lee Jung Il 
Published: August 2021

AbstractBackgroundAutologous nerve grafting has been considered the gold standard for the treatment of irreparable nerve gaps. However, the choice of effective proximodistal orientation of autografts (normal or reversed) is controversial. Therefore, we compared functional and histological outcomes between normal and reversed orientations of autografts in a mouse sciatic nerve model.Materials and methodsThirty C57BL/6J mice weighing 20–25 g were assigned to the donor, normally oriented autograft, and reverse‐oriented autograft groups (n = 10 per group). A 10‐mm section of the sciatic nerve was harvested from a donor mouse. Half the harvested nerve was grafted onto an irreparable gap in a recipient mouse using either a normal or reversed orientation. The sciatic functional index (SFI) was measured biweekly for up to 12 weeks postoperatively. Morphological analysis was performed using immunofluorescence staining for neurofilament (NF) and myelin protein zero (P0) in cross‐sectional and whole‐mount nerve preparations in 12 weeks postoperatively. Additionally, morphological analysis of the tibialis anterior muscle was performed using hematoxylin and eosin staining. NF or P0‐expressing axons were counted and cross‐sectional area (CSA) and minimum Feret's diameter of myofibers were measured.ResultsThe SFI recovered gradually up to 12 weeks after autografting, but there were no significant differences in the SFI between the normal and reversed orientations. The number of NF‐expressing axons in center of graft was significantly higher in the normal orientation than in the reversed orientation (P < .05). However, there were no significant differences in the number and mean intensity of P0‐expressing axons between the orientations. The CSA of myofibers was significantly larger in the normal orientation than in the reversed orientation (P < .05).ConclusionsNormally oriented autografts promote axonal regrowth and prevent neurogenic muscular atrophy compared with reverse‐oriented autografts. However, despite these positive histomorphometric effects, the proximodistal orientation of the autograft does not affect functional outcomes.
Matcha Green Tea Powder does not Prevent Diet‐Induced Arteriosclerosis in New Zealand White Rabbits Due to Impaired Reverse Cholesterol Transport
Authors: Hunjadi Monika , Sieder Claudia , Beierfuß Anja , Kremser Christian , Moriggl Bernhard , Welte René , Kastner Christine , Mern Demissew Shenegelegn , Ritsch Andreas 
Published: August 2021

IntroductionGreen tea is associated with decreased risk for cardiovascular disease and stroke. Matcha is a special kind of powdered green tea known for its use in the Japanese tea ceremony. Due to its influence on lipoprotein parameters, it has been postulated to exert antiatherogenic effects. This study investigates whether it modulates the high‐density lipoprotein (HDL) function and thereby influences the atherogenic process in an animal model with a strong influence on humans' situation.Methods and ResultsAfter a pretreatment phase based on a standard diet, 10 female New Zealand White (NZW) rabbits are fed a high‐fat diet for 20 weeks. The treatment group is additionally administered 1% matcha during the whole experiment. Long‐term matcha treatment leads to lowered HDL cholesterol, impaired cholesterol transport manifested by reduced in vitro cholesterol efflux capacity, reduced cholesteryl ester transfer protein (CETP)‐mediated cholesterol ester (CE) transfer between HDL and triglyceride‐rich particles, and reduced macrophage‐specific in vivo transfer, where ian increased absorption of cholesterol in the liver but a decreased secretion into bile is observed. Pulse wave velocity, assessed by nuclear magnetic resonance, is increased in matcha‐treated animals, and a similar trend is observed for atherosclerotic lesion formation.ConclusionLong‐term matcha green tea treatment of hypercholesterolemic rabbits cause impaired reverse cholesterol transport and increased vascular stiffness, and susceptibility for atherosclerotic lesion development.
The Impact of Enriched Resistant Starch Type‐2 Cookies on the Gut Microbiome in Hemodialysis Patients: A Randomized Controlled Trial
Authors: Kemp Julie Ann , Regis de Paiva Bruna , Fragoso dos Santos Henrique , Emiliano de Jesus Hugo , Craven Hannah , Z. Ijaz Umer , Alvarenga Borges Natalia , G. Shiels Paul , Mafra Denise 
Published: August 2021

IntroductionResistant starch type‐2 (RS2) can mitigate inflammation and oxidative stress in hemodialysis (HD) patients. However, there is still a lack of knowledge on the impact of the RS2 on the gut microbiota community in these patients. Thus, this study aims to evaluate the effects of enriched RS2 cookies on the gut microbiome in HD patients.Methods and ResultsThis comprises a randomized, double‐blind, placebo‐controlled trial of age‐, sex‐, and BMI‐matched patients and controls. The RS2 group receives enriched RS2 cookies (16 g d‐1 of Hi‐Maize 260, Ingredion) for 4 weeks, while the placebo group received cookies made with manioc flour. Fecal microbiota composition is evaluated by the 16S ribosomal RNA gene. Analysis of the microbiota reveals that Pielou's evenness is significantly decreased after RS2 supplementation. Notably, it is observed that RS2 intervention upregulates significantly 8 Amplicon Sequencing Variants (ASV's), including Roseburia and Ruminococcus gauvreauii, which are short‐chain fatty acids (SCFA) producers. Furthermore, it is associated with the downregulation of 11 ASVs, such as the pro‐inflammatory Dialister.ConclusionsRS2 intervention for 4 weeks in HD patients effectively alters SCFA producers in the gut microbiota, suggesting that it could be a good nutritional strategy for patients with chronic kidney disease (CKD) on HD.