bluuebunny/crossref_metadata_2025_split huggingface dataset:
Die „Big Five“ der Invasivität – Sinnhaftigkeit von Drainagen, Sonden und Kathetern in der kolorektalen Chirurgie
Authors: Koch Franziska , Green Martina , Dietrich Melanie , Moikow Lutz , Ritz Jörg-Peter 
Published: October 2021

ZusammenfassungDas perioperative Management bei kolorektalen Resektionen ist häufig durch tradierte Vorgehensweisen und ausgeprägtes Sicherheitsdenken gekennzeichnet. Evidenzbasierte Maßnahmen, wie sie in
Fast-Track- oder ERAS-Programmen etabliert wurden, werden hingegen seltener standardisiert angewandt. Viele Patienten erhalten daher im Rahmen elektiver kolorektaler Chirurgie weiterhin
routinemäßig zentralvenöse Zugänge, Periduralkatheter, Blasenkatheter, Drainagen und/oder Magensonden („Big Five“ der Invasivität). In dieser Arbeit wird die aktuell vorhandene Evidenz zu
diesen Maßnahmen in der kolorektalen Chirurgie dargestellt. Zudem werden Ergebnisse mit Bezug zu den „Big Five“ aus dem eigenen Zentrum vorgestellt. Diese Arbeit zeigt auf, dass die „Big
Five“ der Invasivität klinisch nicht erforderlich und mit fehlender Evidenz belegt sind. Zudem führen sie häufig zu einer Einschränkung des Patienten.
Systematische Übersichtsarbeit: aortale Komplikationen nach intravesikaler Bacillus Calmette-Guérin-Behandlung
Authors: Buerger Matthias , Kapahnke Sebastian , Omran Safwan , Müller Verena , Hinterseher Irene , Greiner Andreas , Frese Jan Paul 
Published: October 2021

Zusammenfassung
Hintergrund Aortale Pathologien nach intravesikaler
BCG-Applikation (BCG: Bacillus Calmette-Guérin) stellen eine
seltene Komplikation nach der Behandlung von nicht muskelinvasiven Harnblasentumoren dar. Das
Ziel dieser Studie war es, eine deskriptive Analyse der bisher publizierten Studien im Rahmen
einer systematischen Übersichtsarbeit durchzuführen und die besonderen Herausforderungen der
Diagnosestellung und Behandlung dieser seltenen Komplikation zu diskutieren.
Material und Methode Es erfolgte eine Literaturrecherche in den
Datenbanken PubMed (1949–2021) und Web of Science (1900–2021) mit den Suchtermini
„mycobacterium“ OR „bovis“ OR „BCG“ AND „aorta“ OR „aneurysm“. In einem stufenweisen
Bewertungsverfahren wurden Publikationen mit folgenden Einschlusskriterien in die finale
Datenauswertung eingeschlossen: Originalarbeit, Volltextverfügbarkeit in englischer oder
deutscher Sprache und aortale Komplikation nach intravesikaler BCG-Instillation.
Ergebnisse In 55 publizierten Arbeiten wurden insgesamt 60
Einzelfälle beschrieben. BCG-induzierte, mykotische Aortenaneurysmen können in allen Segmenten
der Aorta auftreten, wobei das infrarenale Aortensegment am häufigsten betroffen war (65%
aller Fälle). Häufig handelte es sich um sakkuläre (65%) Aussackungen mit (28%) oder ohne
Aortenruptur (63%). Begleitinfektionen in anderweitigen Geweben waren typisch (65%). Die
Diagnose beruhte auf der Kombination aus pathologischen und mikrobiologischen Analysemethoden.
Ein gängiger Therapiealgorithmus war die chirurgische Infektsanierung (85%) und die
antimykobakterielle Therapie (83%). Gleichzeitig durchgeführt führten sie zu einem
Langzeitüberleben von 81%. Eine Protheseninfektion nach initialem Aortenrepair mit
alloplastischem Material (n = 40) entwickelte sich im Verlauf bei 10 Patienten (25%).
Diskussion Die Diagnosestellung beruht auf der Probengewinnung
jeglichen infizierten Gewebes und der Kombination aus passender Anamnese, Klinik und
Laboranalysen. Die Kombination aus chirurgischer Infektsanierung und pharmakologischer
Begleittherapie scheint die besten Ergebnisse zu erzielen. Bereits bei der Initialoperation
sollte die Möglichkeit eines autologen oder allogenen Aortenersatzes evaluiert werden, da das
Risiko eines Protheseninfektes nach Verwendung alloplastischer Materialien hoch ist.
Surgeon-modified Stentgrafts für komplexe Aortenrekonstruktionen – was ist möglich?
Authors: Geisler Antonia , Steiner Sabine , Schmidt Andrej , Scheinert Dierk , Branzan Daniela 
Published: October 2021

Zusammenfassung
Hintergrund Die enge anatomische Beziehung zu den Viszeralgefäßen macht die Behandlung der komplexen thorakoabdominellen Aortenpathologien zu einer Herausforderung. Im Notfall stehen zu ihrer endovaskulären Behandlung Off-the-Shelf-Prothesen und parallele Techniken zur Verfügung, alternativ kann für komplexe Aortenanatomien die Modifizierung herkömmlicher Stentgrafts durch die behandelnden Chirurginnen und Chirurgen erfolgen, im Sinne eines Surgeon-modified Stentgrafts (SMSG). Ziel der vorliegenden Publikation ist die Darstellung der Möglichkeiten und Ergebnisse, die dieses Verfahren bietet.
Ergebnisse Die Planung der Fenestrierungen des SMSG kann mittels manueller Messungen in Centerline of Flow-Rekonstruktionen der aortalen Computertomografie-Angiografie erfolgen. Vereinfacht und standardisiert wird die Planung des SMSG durch die Erstellung von personalisierten 3-D-Aortenmodellen und die Entwicklung von Algorithmen zur automatisierten Ermittlung der idealen Fenestrierungspositionen. Zur Herstellung des SMSG können die meisten zugelassenen Stentgrafts verwendet werden. Für die Anfertigung selbst sind unterschiedliche Techniken beschrieben. Außer der einfachen Fenestrierung ist auch die Erstellung von Mini-Cuffs, Directional Branches und Inner Branches beschrieben, weiterhin die Ergänzung von Diameter reducing Ties und das Vorladen von Führungsdrähten zur Erleichterung der Implantation. Die Behandlung mit SMSG zeigt gute Ergebnisse mit hohen technischen Erfolgsraten um 90–100% und niedriger 30-Tage-Mortalität, vor allem im Vergleich zur
offen-chirurgischen Behandlung ähnlicher PatientInnen. Auch die Rate an Endoleaks ist mit 0–14% akzeptabel. Langzeitergebnisse zur Nachhaltigkeit der modifizierten Stentgrafts sind bislang noch nicht verfügbar.
Schlussfolgerung Die Surgeon-modified Stentgrafts stellen eine sichere und machbare Ergänzung der Palette endovaskulärer Behandlungsoptionen für PatientInnen mit dringlichen komplexen thorakoabdominellen Aortenpathologien dar. Sie können im Rahmen eines individuellen Heilversuches eingesetzt werden und zeigen in der Literatur vielversprechende Ergebnisse.
Photoredox-Catalyzed Ring-Opening Addition Reaction between Benzyl Bromides and Cyclic Ethers
Authors: Hu Jinbo , Kuang Cuiwen , Ni Chuanfa , Gu Yucheng 
Published: October 2021

AbstractA novel nucleophilic reaction between cyclic ethers and benzyl bromides is achieved under photoredox catalysis. The reaction proceeds through a single-electron-transfer (SET) pathway rather than a common SN2 mechanism. By two steps of reduction and oxidation, a benzyl bromide heterolyzes to give a carbocation and bromide ion under mild conditions, and then a cyclic ether captures both the carbo­cation and bromide ion to afford the addition product.
Tandem Nickel-Catalyzed Dimerization/(4+2) Cycloaddition of Terminal Alkynes with Four-Membered Ring Ketones
Authors: Aïssa Christophe , Barday Manuel , Nicolas Eva , Higginson Bradley , Delmotte François , Appelmans Martin 
Published: October 2021

AbstractControlling the behavior of terminal alkynes in metal-catalyzed intermolecular tandem reactions is a formidable challenge despite the potential advantage offered by these strategies in modern synthesis. Herein, we describe that a nickel catalyst enables a tandem process involving the rapid dimerization of terminal alkynes into 1,3-enynes and the cycloaddition of these intermediates with an azetidinone, an oxetanone or benzocyclobutenones. Significantly, the slow or sequential addition of reagents and catalysts is not required to orchestrate their reactivity. These results are in stark contrast with previous cycloadditions of terminal alkynes with strained four-membered ring substrates, which previously led to oligomerization or cyclotrimerization, except in the case of tert-butylacetylene.
Novel Benzothiophene-Based Fluorescent Dye Exhibiting a Large Stokes Shift
Authors: Kaskova Zinaida M. , Bolt Yaroslav V. , Baleeva Nadezhda S. , Nelyubina Yulia V. , Andrianova Anastasia A. , Tsarkova Aleksandra S. 
Published: October 2021

AbstractWe report a simple two-step method for the synthesis of a novel highly fluorescent benzothiophene-based dye comprising five fused rings and exhibiting a large Stokes shift (Δλ = 152 nm or Δν = 5482 cm–1 in ethanol). Structural features of the obtained compound allow easy functionalization of the carbon core and open new possibility for the development of a series of new classes of fluorescent dyes.
A Systematic Approach to Reconciling Data Quality Failures: Investigation Using Spinal Cord Injury Data
Authors: Anantharama Nandini , Buntine Wray , Nunn Andrew 
Published: October 2021

Abstract
Background Secondary use of electronic health record's (EHR) data requires evaluation of data quality (DQ) for fitness of use. While multiple frameworks exist for quantifying DQ, there are no guidelines for the evaluation of DQ failures identified through such frameworks.
Objectives This study proposes a systematic approach to evaluate DQ failures through the understanding of data provenance to support exploratory modeling in machine learning.
Methods Our study is based on the EHR of spinal cord injury inpatients in a state spinal care center in Australia, admitted between 2011 and 2018 (inclusive), and aged over 17 years. DQ was measured in our prerequisite step of applying a DQ framework on the EHR data through rules that quantified DQ dimensions. DQ was measured as the percentage of values per field that meet the criteria or Krippendorff's α for agreement between variables. These failures were then assessed using semistructured interviews with purposively sampled domain experts.
Results The DQ of the fields in our dataset was measured to be from 0% adherent up to 100%. Understanding the data provenance of fields with DQ failures enabled us to ascertain if each DQ failure was fatal, recoverable, or not relevant to the field's inclusion in our study. We also identify the themes of data provenance from a DQ perspective as systems, processes, and actors.
Conclusion A systematic approach to understanding data provenance through the context of data generation helps in the reconciliation or repair of DQ failures and is a necessary step in the preparation of data for secondary use.
Sperm DNA Fragmentation
Authors: Karavolos Stamatios 
Published: October 2021

AbstractSperm DNA fragmentation refers to the accumulation of adducts as well as single- or double-strand DNA breaks and reflects the sperm DNA quality. Current data suggest that there are differences in sperm DNA quality among individuals with high or low fertility, and this observation has led to the idea that testing sperm DNA fragmentation could be a useful test of male fertility. However, sperm DNA fragmentation has become one of the most frequently debated topics in reproductive medicine, as there is no agreement about the optimal way to test for DNA fragmentation, the clinically significant level of sperm DNA fragmentation, as well as the best therapeutic options for infertile men. This article presents current evidence related to sperm DNA fragmentation and its role in managing male infertility.
Influence of Triple-Negative versus Luminal A Breast Cancer Subtype on Choice of Autologous versus Implant-Based Delayed-Immediate Breast Reconstruction
Authors: Dickey Ryan M. , Amaya Joshua , Teotia Sumeet S. , Haddock Nicholas T. 
Published: October 2021

Abstract
Background Triple-negative (TN) and luminal A breast cancer molecular subtypes have divergent clinical and prognostic characteristics for breast cancer patients. Our study aims to compare the reconstructive choice of these two groups from the time they receive a tissue expander (TE) to the time they complete autologous or implant-based breast reconstruction.
Methods A total of 255 patients who underwent delayed-immediate breast reconstruction with TE placement from 2013 to 2017 diagnosed with either TN (n = 73) or luminal A (n = 182) invasive breast cancer subtype seen by two surgeons at a single institution were identified. Preference of autologous and implant-based reconstruction was analyzed, along with TE complications, race, age, body mass index (BMI), smoking, adjuvant therapy, and comorbidities.
Results There was a significant difference in the choice of implant- or autologous-based reconstruction among these two groups (p < 0.05). A greater proportion of luminal A patients underwent implant-based reconstruction (63.47%) and a greater proportion of TN patients underwent autologous-based reconstruction (53.13%). With regard to TE outcomes, there was no significant difference between the two groups with regard to duration of TE placement by reconstructive type or TE surgical complications. Significantly, more TN patients underwent radiation therapy (p < 0.01) and neoadjuvant chemotherapy (p < 0.0001) than luminal A patients. BMI, comorbidities, radiation therapy, and overall TE complications were identified as predictive factors of patients electing for autologous reconstruction over implants.
Conclusion TN breast cancer patients mostly chose autologous-based reconstruction, while luminal A patients chose implant-based reconstruction. Both patient groups carried their TEs for similar duration with similar complication profile. Radiation therapy is likely a major factor in the decision for the type of delayed-immediate reconstruction among this population.
Preterm Newborn Adaptive Responses to Daily Nursing during Neonatal Intensive Care Unit Stay, Associate with Neurodevelopment, 2 Years Later
Authors: Bembich Stefano , Risso Francesco M. , Stan Nicoleta , Lamba Domitilla , Banova Carolina , Pagnini Arianna , Bin Maura , Trappan Antonella , Sanson Gianfranco 
Published: October 2021

Objective This study aimed to evaluate if adaptive responses of very preterm newborns to neonatal intensive care unit (NICU) daily nursing, specifically bathing and weighing procedures are associated with their neurodevelopment after 2 years.Study Design Twenty-six very preterm newborns, with a gestational age <32 weeks, were enrolled. Infants' adaptive responses to daily nursing were evaluated, at 30 to 32 to 35 postmenstrual age (PMA) weeks by an observational sheet. Neurodevelopment was assessed at 24 months of corrected age by the Bayley Scales of Infant and Toddler Development, third edition. Autonomic, motor, and self-regulatory responses to NICU nursing were analyzed by Spearman's correlation coefficient and multivariate linear regression with Bayley's cognitive, language, and motor scales.Results Significant (p < 0.05) positive correlations of self-regulatory and autonomic responses to nursing with all Bayley's scales were found at 30- and 32-week PMA. At 35-week PMA, only self-regulatory responses had significant positive correlations with all Bayley's scales. When adjusted for birth weight and sex, the significant associations were confirmed only at 30- and 32-week PMA.Conclusion Very preterm newborn adaptive responses to NICU daily nursing reveal to be positively related to forthcoming neurodevelopment 2 years later, as early as the 30-week PMA. Helping preterm babies to adapt to daily NICU nursing may promote their future neurobehavior.Key Points
Miniaturized wireless, skin-integrated sensor networks for quantifying full-body movement behaviors and vital signs in infants
Authors: Jeong Hyoyoung , Kwak Sung Soo , Sohn Seokwoo , Lee Jong Yoon , Lee Young Joong , O’Brien Megan K. , Park Yoonseok , Avila Raudel , Kim Jin-Tae , Yoo Jae-Young , Irie Masahiro , Jang Hokyung , Ouyang Wei , Shawen Nicholas , Kang Youn J. , Kim Seung Sik , Tzavelis Andreas , Lee KunHyuck , Andersen Rachel A. , Huang Yonggang , Jayaraman Arun , Davis Matthew M. , Shanley Thomas , Wakschlag Lauren S. , Krogh-Jespersen Sheila , Xu Shuai , Ryan Shirley W. , Lieber Richard L. , Rogers John A. 
Published: October 2021

Significance
Early detection of infant neuromotor pathologies is critical for timely therapeutic interventions that rely on early-life neuroplasticity. Traditional assessments rely on subjective expert evaluations or specialized medical facilities, making them challenging to scale in remote and/or resource-constrained settings. The results presented here aim to democratize these evaluations using wireless networks of miniaturized, skin-integrated sensors that digitize movement behaviors and vital signs of infants in a cost-effective manner. The resulting data yield full-body motion reconstructions in the form of deidentified infant avatars, along with a range of important cardiopulmonary information. This technology approach enables rapid, routine evaluations of infants at any age via an engineering platform that has potential for use in nearly any setting across developed and developing countries alike.
COVID-19 lockdowns drive decline in active fires in southeastern United States
Authors: Poulter Benjamin , Freeborn Patrick H. , Jolly W. Matt , Varner J. Morgan 
Published: October 2021

Significance
The coronavirus pandemic, COVID-19, led to strict social-distancing guidelines that severely impacted human livelihood and economic activity. Workplace closures reduced travel, and early in spring 2020, improvements in air and water quality, reduced seismic activity, and reductions in greenhouse gas emissions were observed. COVID-19–related shutdowns emerged at the beginning of the prescribed fire season in the southeastern United States, where 80% of fires are human caused. Using active fire satellite observations and fuel treatment statistics, we estimated a 21% reduction in active fires from March to December 2020 (up to 40% on federal lands). This reduction in active fire may increase fire risk in the future and is detrimental to biodiversity and other ecosystem services inherent to fire-dependent ecosystems.
On the mechanisms of the influence of preliminary ionization on the plasma dynamics of nanosecond capillary discharges and the properties of discharge-based EUV lasers
Authors: Eliseev S , Samokhvalov A , Zhao Y P , Burtsev V 
Published: October 2021

Abstract
In this paper, we present the results of numerical investigations into the influence of preionization on the properties of extreme ultraviolet (EUV) lasers based on nanosecond capillary discharges. Prior to application of the main current pulse, gas inside the capillary is usually preionized by a separate current pulse with longer duration and lower amplitude, which creates plasma with minimal density on the capillary axis and maximal at the capillary wall. Magnetohydrodynamic simulations were performed for a range of prepulse parameters that defined different degrees of inhomogeneity of this initial profile. It was found that the plasma density distribution at the start of the main current pulse affects the cylindrical shock wave that takes place during the compression stage of a capillary discharge: A lower degree of radial inhomogeneity results in a steeper front of the shock wave. It is further shown that a steeper wave front results in a more concave electron density profile moments before the shock wave collapses on the capillary axis, when the EUV laser pulse presumably takes place, which may lead to a decrease in the rate of refraction losses. The proposed interpretation of the obtained numerical results correlates well with the available experimental data on the dependence of EUV laser pulse intensity and duration on the preliminary pulse amplitude.
The validity of triple contact line theory from hydrophilic to superhydrophobic surfaces
Authors: Taher Md Abu , Rajput Vinod K , Krishnan P K Navanith , Naraharisetty Sri Ram G 
Published: October 2021

Abstract
The anisotropic droplet formulation is generalized from hydrophilic to superhydrophobic surfaces. An experimental method to calibrate the ellipsoidal droplet volume on both hydrophilic and hydrophobic surfaces is presented. A broad range of contact angles (CAs) is produced on the copper and stainless-steel surfaces using femtosecond laser patterning. The effects of line spacing between the laser scanning on the formation of anisotropic CAs are discussed. The comparative study of the evolution of anisotropic CAs and droplet’s spreading dynamics are studied on both surfaces. According to the triple contact line (TCL) theory, CAs are determined by the TCL between droplet and surface rather than the contact area. We presented the mathematical formalism and the experimental validity of the TCL theory on ellipsoidal droplets over a broad range of CAs, from as low as 37°–172°. This work experimentally validated the TCL theory over a broad range of CAs with good confidence.
Critical study of partial discharge inception in voids: statistical behavior to stochastic nature
Authors: Zhang Rui , Zhang Qiaogen , Zhou Junjie , Guo Chong , He Xiaohui , Wu Zhicheng , Wen Tao 
Published: October 2021

Abstract
Although many studies have been done and advanced progress has been made in understanding partial discharge (PD) behavior in the void, this is not the case firinception of PD, especially its stochastic nature. The statistical behaviors of PD inception voltage (PDIV) and inception time delay (PDTD) inside the void were investigated in this study through repeated tests to observe the stochastic nature of PD inception. The results show that the PDIV and PDTD of the void are highly dispersed and obey Weibull and exponential distributions, respectively. The significant dispersion of PDIV can be attributed to the statistical time delay of PD inception. The lengthy inception delay is attributable to a lack of free electrons. The exponential distribution of PDTD indicates that free-electron generation is completely random; further, the stochastic nature of void PD inception is determined by the supply of free electrons. The test method (voltage rise rate, test time, and test time interval), void parameters (size, material, and surface condition), and background radiation determine PD inception by affecting the volume ionization or surface-emission process providing free electrons. Enhanced background ionization or significant increase in test voltage and test time allow for the effective detection of void defects during PD tests. This work contributes to an empirical understanding of the physical process of PD inception in voids and improving existing PD testing technologies.
Critical curves in NiFe/FeMn bilayers with varying antiferromagnetic layer thickness
Authors: Adams D J , Cimpoesu D , Benit S , Maurin D , Kern P R , Carara M , Spinu L 
Published: October 2021

Abstract
The effect of antiferromagnetic (AF) layer thickness on exchange bias was studied in a series of NiFe(50 nm)/FeMn(t) bilayers through both irreversible and reversible experiments at room temperature. The exchange bias was evaluated in the sample plane both through measurement of the major hysteresis loops and probing the reversible susceptibility. The critical curve was constructed to map the angular dependence of the magnetization switching and exchange bias, which is found to evolve as a function of AF layer thickness. Ferromagnetic resonance absorption was measured at several frequencies and angles, and angular-dependent absorption curves were plotted. A comparison is made between the recorded exchange bias using the three methods. The measurements reported are supported by simulations under a generalized Stoner–Wohlfarth model, and general limitations of the experiment are discussed.