bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Osteocalcin in Middle-Age Women With and Without Type2 Diabetes Mellitus
Authors: Hadeer I. Jassim  , Ammar L. Hussein  
Published: December 2024

Background: Diabetes mellitus is a chronic disease that affects people of all ages. It's caused by deficiencies in insulin action and secretion, leading to long-term hyperglycemia. This can harm key organs such as the kidneys, heart, eyes, nerves, and blood vessels. Managing diabetes requires significant lifestyle changes and can impact both the patient and their family. Small and bone-specific, osteocalcin (OCN) is a non-collagen protein that is mostly present in bone. It is a sensitive marker of bone formation and primarily attaches to the extracellular matrix of bone after being carboxylated. Small amounts of OCN are also released into the bloodstream, where it aids in glucose and fat metabolism.
Objective: Our study aimed to examine the effect of Osteocalcin, Parathyroid hormone, Estrogen and HbA1c on middle-aged women who had type 2 diabetes compared to those who did not.
Patients and Methods: The study involved 90 middle-aged women, including 60 with type 2 diabetes, and 30 healthy women. The Sandwich enzyme-linked immunosorbent assay was used to measure OCN, PTH, and E2 hormone levels in women with and without type 2 diabetes. HbA1c levels were measured using the Cobos system. The statistical analysis was performed using SPSS software.
Results: In T2DM women, serum OCN, PTH, E2, and HbA1c levels were compared with non-diabetic women. T2DM women had significantly lower levels of serum OCN and PTH, and significantly higher levels of HbA1c than healthy women. Serum E2 levels were also significantly lower in T2DM women. OCN had a positive correlation with HbA1c and negative correlations with PTH and E2.
Conclusion: Significant change was detected in this study in the level of OCN, PTH and E2 between patients and controls. Investigations of serum OCN can be participated in the future as predictive marker for osteoporosis in diabetic women.
Keywords: Osteocalcin, parathyroid hormone, estrogen, Type2 diabetes mellitus.
The Existence of Health Literacy in Science Education: A Systematic Literature Review
Authors: Salim Fitrah Amalia , Mahanal Susriyati , Susanto Hendra 
Published: December 2024

Health literacy is an interesting thing to study in science learning. The purpose of this Systematic Literature Review (SLR) is to determine the trend of health literacy publications in scopus indexed journals and the potential for empowering health literacy in science learning. The keywords used were "health literacy" and "student" on the search menu in the scopus database and met the criteria for further analysis as many as 22 articles. Researchers use the PRISMA model to include and exclude articles. The findings obtained are the trend of health literacy publications in science learning in the form of types of research, year distribution, keywords, researcher nationality and international collaboration. The potential for health literacy in science learning can enrich students' knowledge about disease prevention, the integration of science learning with technology can improve students' skills in obtaining health information, community involvement with science learning has the potential to increase student awareness and responsibility, innovative science learning supports the empowerment of student health literacy. The implication in this study is that health literacy can be empowered through innovative learning models in science learning.
Conceptual foundations of I. Ya. Yakovlev's didactics and modern technologies of independent work of students in a pedagogical university
Authors: Danilova Lyudmila Nikolaevna 
Published: December 2024

The article is devoted to the study of the conceptual foundations of I.Ya. Yakovlev's didactics. The work presents an analytical description of the technologies of independent work, self-development, self-education in the pedagogical system of the educator of the Chuvash people. Based on the content of federal state educational standards of higher education, the author proves the relevance of I.Ya. Yakovlev's didactic system in modern conditions of the implementation of the &quot;Core of Higher Pedagogical Education&quot;, their innovative nature, the effectiveness of the organization of the educational process in the Simbirsk Chuvash Teachers' School. The work presents the results of the analysis of modern curricula in the direction of training &quot;Psychology and Pedagogy of Preschool Education&quot; for the presentation of a description of technologies and the amount of time for completing assignments for independent work. The study of I.Ya. Yakovlev's didactic system is built taking into account the knowledge, ethnocultural, personological paradigms and on the principles of consistency and competence. The results of the study, obtained on the basis of theoretical analysis of pedagogical literature and normative regulators of education, have a methodological nature, are consonant with the requirements for the results of the formation of universal, general professional and professional competencies. The author presented a substantive analysis of the author's and advanced technologies for the 18th century for organizing the classroom and extracurricular work of students: reading, retelling, taking notes on pedagogical literature, research, project, essay-reasoning, developing logic and critical thinking. The described technologies require reconstruction in new socio-cultural conditions, they can be recommended for use in the educational process of a modern university.
ВИЩА ОСВІТА УКРАЇНИ В УМОВАХ РОСІЙСЬКО – УКРАЇНСЬКОЇ ВІЙНИ В УКРАЇНСЬКОМУ ЗАКОНОДАВСТВІ
Authors: КАНІЩЕВ Григорій , ТУР Ірина 
Published: December 2024

публікацію присвячено питанням законодавчих змін у вищій освіті України під впливом нинішньої російсько – української війни. Підкреслюється, що ця війна призвела до великих зрушень у житті нашої держави. Зокрема, до переміщення вищих навчальних закладів по території України. Всі зазначені вище зміни не могли не призвести до великих зрушень у системі вищої освіти нашої держави. Насамперед, це розірвання відповідних наукових і навчальних зв’язків із країною – агресором. Також до таких змін слід віднести перебудову роботи українських науковців, викладачів і студентів відповідно до реалій військового часу. Як матеріал, використано аналітичні звіти щодо стану української науки і освіти в умовах воєнного стану, підготовлені українськими науковцями, а також нормативно – правові акти України – закони і підзаконні акти – що регламентують діяльність у вищезгаданій сфері.
ДЕЯКІ АСПЕКТИ БЕЗПЕКИ ОСВІТНЬОГО СЕРЕДОВИЩА У КОНТЕКСТІ НАЦІОНАЛЬНОЇ БЕЗПЕКИ УКРАЇНИ
Authors: РЮТІН Віталій 
Published: December 2024

Обґрунтована безпекова проблематика освітнього середовища в умовах військового стану. Освітнє безпекове середовище представлено відносно понять «державна безпека» та «національна безпека». Наведені кількісні характеристики дають підстави розглядати негативні тенденції в освітньому середовищі як потенційні загрози національній безпеці та національним інтересам України
НАВЧАННЯ В БЕЗПЕЦІ: НОВА РЕАЛЬНІСТЬ ДЛЯ УКРАЇНСЬКОЇ ОСВІТИ
Authors: ЯЗАН Наталія , ФІЛІПЕНКО Наталія 
Published: December 2024

У доповіді розглянуто важливі аспекти створення безпечних умов для учасників освітнього процесу. Особливу увагу приділено не лише стандартним заходам, таким як охорона території, впровадження систем відеоспостереження та тривожних кнопок, а й впровадженню експериментальних проєктів. Такі проєкти реалізуються у тісній взаємодії з усіма причетними службами та відомствами, включаючи правоохоронні органи, соціальні служби, місцеві громади та адміністрації закладів освіти. Новаторські підходи до забезпечення безпеки спрямовані на підвищення рівня комунікації між учасниками освітнього середовища, вдосконалення профілактичних заходів і створення єдиної системи реагування на потенційні загрози.
Indonesian midwives’ experiences in delivering childbirth services: A qualitative study
Authors: Ningrum Mudy , Soraya Desi 
Published: December 2024

Background: Quality healthcare services during childbirth are essential for the safety of mothers and newborns. Despite global efforts to improve maternal and neonatal health, many challenges remain, particularly in low-resource settings. Midwives play a vital role in ensuring safe childbirth and improving maternal and neonatal outcomes.
Objective: This study aimed to explore midwives’ experiences in delivering childbirth services in Ungaran City, Central Java Province, Indonesia.
Methods: A descriptive phenomenological was employed. Data were collected in June 2021 through semi-structured interviews with six midwives. Colaizzi’s methods were used to analyze the data.
Results: The findings revealed two main themes: 1) Challenges commonly faced in childbirth services, which include subthemes of economic and pragmatic concerns, socio-cultural beliefs and traditions, perceived necessity of midwifery services, access to services, and public perception of the knowledge and skills of childbirth providers; and 2) Reasons for choosing home childbirth, with subthemes of economic factors, cultural and ritualistic perceptions, access to health facilities, and comfort.
Conclusion: This study highlights the importance of addressing economic and socio-cultural factors to improve maternal healthcare in rural areas. Collaboration between midwives and traditional birth attendants can enhance trust and ensure safer outcomes. Future studies are needed to explore how to integrate these practices for improved healthcare delivery.
The extent of sexual and reproductive health services utilization among adolescents in Abuja, Nigeria: A cross-sectional study
Authors: Onuh Josephine Akor , Pacial Rachelle Gay Rosario 
Published: December 2024

Background: Access to Sexual and Reproductive Health Services (SRHS) is crucial for adolescent health, yet their utilization remains low in many regions. In Abuja Municipal Area, the extent of SRHS use among female adolescents is unclear, prompting this study to assess the utilization level.
Objective: This study aimed to evaluate the extent of SRHS utilization among female adolescents in Abuja Municipal Area, Nigeria.
Methods: A cross-sectional descriptive study was conducted involving 214 female adolescents. Data were collected from February to July 2023 using a structured questionnaire, with responses analyzed to determine the extent of SRHS utilization. Statistical analysis was done using means, t-tests, and ANOVA to assess the impact of marital status, educational level, and other factors.
Results: The overall SRHS utilization among adolescents was low, with an average weighted mean of 1.50, categorized as "Not Extensive." Married adolescents used more SRHS than single adolescents, with a significant difference (t = -7.07, p <0.001) in services such as antenatal care (mean = 2.22 for married vs. 1.37 for single, p <0.001), contraceptive counseling (mean = 1.92 for married vs. 1.33 for single, p <0.001), and postnatal care (mean = 2.10 for married vs. 1.35 for single, p <0.001). Educational level did not significantly influence SRHS utilization, with p-values for contraceptive counseling (p = 0.287) and STI counseling (p = 0.155) showing no significant differences across primary, secondary, and tertiary education groups. Psychological, socio-cultural, and economic factors were major barriers to accessing SRHS.
Conclusion: The SRHS utilization among female adolescents in Abuja is insufficient, with marital status being a significant factor in service usage. To improve access, there is a need for targeted interventions, including education on SRHS and the development of informational materials, such as brochures, to enhance awareness and reduce barriers to access.
Цифровые платформы как инструмент реализации бартерных сделок в условиях ужесточения экономических санкций
Authors: Торжевский К.А. 
Published: December 2024

В статье рассматриваются возможности использования цифровых платформ в бартерной торговле. Исследуется роль бартера на современном этапе в условиях ужесточения экономических санкций и торговых войн на примере цифровой платформы, получившей патент в бюро США и Японии на перемещение ценностей с помощию технологии распределенного реестра (блокчейн) и являющейся интеллектуальной собственностью ее создателя.
The article discusses the possibilities of using digital platforms in barter trading. The role of barter at the present stage in the context of tightening economic sanctions and trade wars is being investigated. As an example, Veritaserum digital platform is given, which is a potentially disruptive technology, disintermediating banks, lawyers, stock and commodity exchanges, any centralized authorities.
ПЕПТИДНАЯ РЕГУЛЯЦИЯ КЛЕТОЧНОГО СТАРЕНИЯ
Authors: Ивко О.М. 
Published: December 2024

Клеточное старение — неспособность структур к пролиферации (дальнейшему делению) и репарации повреждений при сохранении метаболической активности. Ключевыми хорошо известными факторами клеточного старения являются процессы повреждения ДНК, укорочения теломер, развитие окислительного стресса и эпигенетических изменений. Вышеуказанные факторы провоцируют развитие провоспалительной среды, приводящей к ошибкам экспрессии генов и метаболической дизрегуляции, тем самым влияя на процесс развития возраст-ассоциированных заболеваний, способст вующих патологическим изменениям функций тканей и органов. Современные подходы фармакотерапии, направленной на замедление процессов клеточного старения, в основном сосредоточены на трех ключевых стратегиях: воздействие на сигнальные пути, обусловливающие клеточное старение, а также на конкретные факторы клеточного цикла (белковые структуры — рецепторы, белкипереносчики, биорегуляторы и так далее), улучшение элиминации клеточного «мусора» иммунной системой. У лиц пожилого возраста нарушается биорегуляция различных процессов клеточного цикла, а применение полипептидных комплексов способствует поддержанию нормальных функций организма, способствуя стимуляции синтеза белков-маркеров функциональной активности клеток.
Cellular aging is the inability of structures to proliferate (further division) and repair damage while maintaining metabolic activity. The key well-known factors of cellular aging are the processes of DNA damage, telomere shortening, the development of oxidative stress and epigenetic changes. The above factors provoke the development of a pro-inflammatory environment, leading to errors in gene expression and metabolic dysregulation, thereby affecting the development of age-related diseases that contribute to pathological changes in the functions of tissues and organs. Modern pharmacotherapy approaches aimed at slowing down the processes of cellular aging are mainly focused on three key strategies: influencing the signaling pathways that cause cellular aging, as well as specific factors of the cell cycle (protein structures — receptors, carrier proteins, bioregulators, and so on), improving the elimination of cellular debris by the immune systern pharmacotherapy approaches aimed at slowing down the processes of cellular aging are mainly focused on three key strategies: influencing the signaling pathways that cause cellular aging, as well as specific factors of the cell cycle (protein structures — receptors, carrier proteins, bioregulators, and so on), improving the elimination of cellular debris by the immune system. In the elderly, the regulation of various processes of the cell cycle is disrupted, and the use of polypeptide complexes helps to maintain normal body functions by stimulating the synthesis of proteins-markers of cell functional activity.
ИНСОМНИЯ КАК ТРАНСДИАГНОСТИЧЕСКИЙ ФЕНОМЕН У ПОЖИЛЫХ С ДЕПРЕССИВНЫМИ И ТРЕВОЖНЫМИ РАССТРОЙСТВАМИ
Authors: Мизинова Е.Б. , Караваева Т.А. , Васильева А.В. , Радионов Д.С. 
Published: December 2024

В статье дана характеристика форм, причин и последствий бессонницы у пожилых. Приведены клинические особенности диссомнических нарушений при коморбидных депрессивных и тревожных расстройствах как чаще всего встречающейся психической патологии позднего возраста. Рассмотрены подходы российских и зарубежных авторов к диагностике и лечению инсомнии у пожилых. Проведен анализ преимуществ и недостатков фармакологического и психотерапевтического подходов в терапии нарушений сна в пожилом возрасте при коморбидных аффективных нарушениях.
The article describes the forms, causes and consequences of insomnia in the elderly. It shows the clinical features of dyssomnic disorders in comorbid depressive and anxiety disorders, as the most common mental pathology of old age. The approaches of Russian and foreign authors to the diagnosis and treatment of insomnia in the elderly are considered. The analysis of the advantages and disadvantages of pharmacological and psychotherapeutic approaches in the treatment of sleep disorders in old age with comorbid affective disorders is carried out.
ВЛИЯНИЕ ЭФИРНЫХ МАСЕЛ РАСТЕНИЙ НА УМСТВЕННУЮ РАБОТОСПОСОБНОСТЬ ПОЖИЛЫХ ЛЮДЕЙ
Authors: Ярош А.М. , Батура И.А. , Тонковцева В.В. , Синицын А.В. , Коваль Е.С. , Огаркова Е.-Е.В. 
Published: December 2024

Изучено влияние эфирных масел (ЭМ) 22 видов и сортов эфиромасличных растений на умственную работоспособность людей пожилого возраста при вдыхании ими воздуха, содержащего ЭМ в газообразном состоянии в концентрации 1 мг/м3 воздуха. Для исследования были использованы тест распознавания слов с пропущенными буквами и корректурная проба. Установлено, что распознание слов с пропущенными буквами стимулируется при небольшой (10–20 мин) длительности воздействия ЭМ, а затем эффект угасает. Напротив, наибольшее увеличение темпа выполнения корректурной пробы приходится на 30-минутный срок воздействия масел. ЭМ розмарина лекарственного, чабера садового, котовника кошачьего, бархатцев мелких, мяты перечной сортов Удайчанка и Украинская, гвоздичного дерева ускоряют как распознание слов с пропущенными буквами (при кратковременном воздействии), так и скорость выполнения теста корректурной пробы (при длительном воздействии).
The effect of essential oils (EOs) of 22 species and varieties of essential oil plants on the mental performance of elderly people when they inhaled air containing EOs in a gaseous state at a concentration of 1 mg/m3 of air was studied. For the study, a word recognition test with missing letters and a proofreading test were used. It has been established that recognition of words with missing letters is stimulated for a short (10–20 min) duration of exposure to EOs, and then the effect fades away. On the contrary, the greatest increase in the pace of performing the correction test occurs during the 30-minute period of exposure to EOs. EOs of rosemary, garden savory, catnip, small marigolds, peppermint varieties Udaychanka and Ukrainian, and cloves accelerate both the recognition of words with missing letters (with shortterm exposure to EO) and the speed of completing the proofreading test (with long-term exposure to EO).
GOOGLE TEACHABLE MACHINE: PEMANFAATAN MACHINE LEARNING BERBASIS CNN UNTUK IDENTIFIKASI CEPAT BATUAN MINERAL KALSIT, KUARSA DAN MAGNETIT
Authors: Johannes Albert Zicko , Bukit Minsyahril , Betan Agustinus D D , Tarigan Jonshon 
Published: December 2024

Google Teachable Machine adalah aplikasi berbasis website yang dapat dimanfaatkan penggunanya untuk membuat suatu model machine learning tanpa perlu menulis kode. Aplikasi ini memanfaatkan Jaringan Saraf Konvolusional (CNN) dalam prosesnya. Pada penelitian ini dilakukan pemanfaatan Teachable Machine untuk membuat model machine learning yang dapat mengidentifikasi batuan mineral khususnya magnetit, kalsit, dan kuarsa. Prosedur penelitian dilakukan melalui beberapa tahapan yaitu: Pengumpulan Sampel, Klasifikasi Sampel (Dataset), Pelatihan Model (Training), dan Proses Evaluasi. Pengumpulan data sampel berupa gambar batuan mineral diperoleh dan diunduh dari Google. Data tersebut kemudian dibagi menjadi tiga kelas mineral yaitu magnetit, kalsit, dan kuarsa yang digunakan sebagai input pada aplikasi Teachable Machine. Pelatihan model pada Teachable Machine menggunakan input epochs 100, batch size 64, dan learning rate 0.0001. Hasil pemodelan Teachable Machine kemudian dievaluasi dan menunjukkan bahwa model yang diperoleh dapat mengenali mineral magnetit, kalsit, dan kuarsa dengan akurasi, presisi, recal, spesifisitas, dan nilai F1 rata-rata sebesar 91.11% (86.67%), 87.30%, 86.67%, 93.33%, dan 86.50%. Penelitian ini menunjukkan bahwa pemanfaatan Teachable Machine membantu melakukan identifikasi cepat, akurat dan mudah sehingga dapat memberikan kontribusi dalam mempercepat proses analisis batuan mineral, pengambilan keputusan, dan pengembangan strategi eksplorasi. Selain itu hasil ini menunjukkan aplikasi ini memiliki potensi pengembangan yang lebih luas dalam bidang-bidang ilmu yang beragam.
Kekerasan dalam Rumah Tangga (KDRT) yang Terjadi di Kota Bitung
Authors: Adam Rahmat S. , Mallo Nola T. S. , Tomuka Djemi 
Published: December 2024

Abstract: According to the Ministry of Women's Empowerment and Child Protection (PPPA) through the Online Information System for the Protection of Women and Children (SIMFONI PPA), in North Sulawesi 2023, the most dominant violence based on the location of the incidence is household. Bitung is the area with the second highest number of domestic violence cases in 2023. This study aimed to obtain the description of domestic violence cases in Bitung 2022. This was a retrospective and descriptive study using secondary data taken from the Women's Empowerment and Child Protection Service and Police Department in Bitung. The relationships between variables were analayzed with the chi-square test. The results showed that the majority of victims were children (74.5%) with the type of penance violence (45.8%). Most often the perpetrator was the father (38.2%). The chi-square test obtained p=0.008 for the relationship between victim and all types of violence; p=0,000 for the relationship between the relation of perpetrator and victim and all types of violence; and p=0.542 for the relationship between location and all types of violence. In conclusion, the majority of domestic violence in Bitung is penance violence with children as the victims, and the father as perpetrator. There is no relationship between location and all types of violence.
Keywords: types of violence; domestic violence; victim

Abstrak: Kementerian Pemberdayaan Perempuan dan Perlindungan Anak (PPPA) melalui Sistem Informasi Online Perlindungan Perempuan dan Anak (SIMFONI PPA) melaporkan bahwa di Sulawesi Utara pada korban kekerasan per tahun 2023 yang paling mendominasi berdasarkan tempat kejadian ialah rumah tangga. Kota Bitung merupakan daerah dengan posisi ke-2 kasus kekerasan per tahun 2023. Penelitian ini bertujuan untuk menganalisis kasus KDRT di Kota Bitung. Jenis penelitian ialah deskrptif restrospektif dengan menggunakan data sekunder diambil dari Dinas Pemberdayaan Perempuan dan Perlindungan Anak Kota Bitung serta Polisi Resort Kota Bitung tahun 2022. Uji statistik terhadap hubungan variabel menggunakan uji chi-square. Hasil penelitian mendapatkan bahwa mayoritas korban ialah kategori anak (74,5%) dengan jenis kekerasan penelantaran (45,8%) serta pelaku paling banyak ialah ayah (38,2%). Hasil uji chi-square mendapatkan nilai p=0,008 pada variabel korban dengan semua jenis kekerasan; p=0,000 pada variabel hubungan pelaku dengan korban terhadap semua jenis kekerasan; dan p=0,542 pada hubungan antara variabel kecamatan dengan semua jenis kekerasan. Simpulan penelitian ini ialah mayoritas kekerasan dalam rumah tangga yang terjadi di Kota Bitung ialah penelantaran dengan korban terbanyak ialah anak, pelaku yang berstatus ayah, namun hubungan wilayah kejadian dari setiap kasus tidak berkontribusi dalam terjadinya kekerasan dalam rumah tangga.
Kata kunci: jenis kekerasan; kekerasan dalam rumah tangga; korban