bluuebunny/crossref_metadata_2025_split huggingface dataset:
KOMITMEN MANAJEMEN, PENGETAHUAN K-3 & SIKAP K-3 DENGAN PENERAPAN SMK-3 PADA PEKERJA
Authors: Sidauruk Silvana 
Published: January 2021

The application of sophisticated technology, machines, installations, and hazardous materials are increasing in relation to industrialization. These could facili-tate the production activities, however they could also give potential danger. This research is intended to identify the correlation and influence between commitment of management, the knowledge of safety, and attitude toward safety in regards to the implementation of OHS management system among the workers of PT. X Batam Shipyard Company. This is an analytical correlative research with a cross-sectional design. The research subjects are 63 persons, consist of supervisors and employees who work at the production division of PT. X Batam. The type of analy-sis used Pearson Product Moment Correlation and multiple regression tests. The result shows that there is a positively significant correlation and influence between commitment of management, the knowledge of safety, and attitude toward safety in regards to the implementation of OHS management system (R = 0651; p = 0.000), which has 42,4% contribution simultaneously. The result shows that commitment of management give the higher correlation and influence to the implementation of OHS management system (r=0,495; p=0,000), which has 22,13% contribution, followed by attitude toward safety (r=0,372; p=0,003) which has 12,17% contribution, and the knowledge of safety (r=0,321; p=0,010) which has 8,1% contribution.
Investigation of Fermentation Regimes for the Production of Low-alcohol and Non-alcohol Beers
Authors: Petelkov Ivan , Shopska Vesela , Denkova-Kostova Rositsa , Ivanova Kristina , Kostov Georgi , Lyubenova Velislava 
Published: January 2021

The combination of modified mashing method and arrested fermentation for the production of low-alcohol and non-alcohol beers was studied. Therefore, five regimes for fermentation of wort with reduced fermentable sugar content with top-fermenting yeast strain at low temperatures and pitching rates were investigated. According to the fermentation dynamic results the decrease in the fermentation temperature from 10 °C to 5 °C at pitching rate of 109 Colony Forming Units cm−3 ( CFU cm−3 ) led to significantly reduced concentrations of ethanol and secondary metabolites in beer. The temperature decrease from 10 °C to 7 °C at pitching rate of 107 CFU cm−3 resulted in a decrease in the alcohol concentration and increase in all the secondary metabolite concentrations except for the vicinal diketones concentration. Data show that yeast biomass does not grow at 5 °C and at inoculum concentration of 107 CFU cm−3, which makes fermentation impossible. Fermentation kinetics using Monod's model supplemented with product inhibition was also investigated. Up to 1.7 % of alcohol accumulates in the beer in some of the variants within 7 days. At low fermentation temperatures, yeast biomass utilizes part of the substrate to maintain its vital activity under stress fermentation conditions, which leads to a reduction in the amount of alcohol synthesized. The synthesis and reduction of the secondary metabolites was delayed compared to conventional beer fermentation. The sensory evaluation of the beers produced showed that the most appealing beer was the one produced at 10 °C and pitching rate of 109 CFU cm−3.
Estimulación multisensorial temprana desde la metodología Montessori: Reflexiones para su aplicación en condiciones de distanciamiento social.
Authors: Sailema Torres Ángel Aníbal , Acosta Bones Silvia Beatriz , Zapata Mocha Esmeralda Giovanna , Estupiñan Guamani Milena Aracely 
Published: January 2021

Introducción: Dentro de las prioridades más importantes está la atención a la primera infancia. Con la llegada del COVIC 19, esto se ha visto grandemente afectado, provocando la necesidad de replantearse de diferentes maneras. En el contexto educativo debido al distanciamiento social ha provocado tener que migrar de la modalidad presencial a la online. Objetivo: Reflexionar sobre la factibilidad de la Metodología Montessori, para la estimulación multisensorial de niños con o sin necesidades educativas especiales, en condiciones de distanciamiento social. Metodología: El estudio siguió una metodología descriptiva, no experimental, mediante el empleo de métodos teóricos y empíricos y la RSL (Revisión Sistemática de Literatura), permitió consultar 46 fuentes obteniendo como Resultados: La Identificación de 13 estudios potenciales que contribuyeron a sistematizar los fundamentos teóricos sobre la factibilidad de la Metodología Montessori, facilitando la concreción de 4 teorías esenciales: 1. Relación del Diagnóstico con el proceso de Intervención en edades tempranas. 2. La estimulación multisensorial base del desarrollo Infantil. 3. Los materiales y recursos didácticos favorecen el aprendizaje significativo y el desarrollo integral del niño.4. La estimulación multisensorial temprana a niños con necesidades educativas especiales asociadas o no a discapacidad en condiciones de distanciamiento social un desafío permanente. Conclusiones: La sistematización de las teorías precedentes en torno a la Metodología Montessori resaltan su factibilidad, pertinencia y aplicabilidad para la estimulación multisensorial temprana en niños con o sin necesidades educativas especiales, sin embargo se evidencian limitaciones debido a los escasos estudios realizados en relación con su aplicabilidad en condiciones de aislamiento social, a esto se une la necesidad de capacitación y preparación del personal docente y del contexto familiar para su optimización, así como la migración de los modelos pedagógicos presenciales hacia modelos pedagógicos virtuales.
El comercio justo en el contexto del desarrollo sostenible
Authors: Salas Castelo Edison Marcelo , Arguello Guadalupe Carla Sofía , Guapi Auquilla Andrea Patricia 
Published: January 2021

Introducción. El comercio justo nace de la necesidad de una alternativa al comercio tradicional desde la visión capitalista, el cual no ha encontrado la forma de impulsar el desarrollo de las naciones de manera equitativa. Mas aun, un gran número de autores subrayan la responsabilidad del comercio tradicional sobre el crecimiento de la desigualdad y el empobrecimiento de muchas naciones a nivel global. Ante este fracaso del comercio tradicional, el comercio justo surge para plantear una forma nueva de intercambio comercial basado en el respeto, el diálogo, la equidad entre productores y consumidores y la responsabilidad ambiental Objetivos. Analizar los principios del comercio justo, sus principios, los obstáculos para su adopción y aplicación y las tareas a realizar y la articulación que existe entre el comercio justo y los objetivos de desarrollo sostenible propuestos por el Programa de Naciones Unidas para el Desarrollo. Metodología. Para la realización de este trabajo de investigación se empleó la metodología de análisis documental, incluyendo documentos relevantes sobre el objeto de investigación. Diferentes recursos bibliográficos fueron analizados, con especial énfasis en el contexto latinoamericano. Resultados. Existen muchas barreras para que los pequeños productores adopten e implementen proyectos bajo este esquema de comercio alternativo, tales como costos demasiado elevados de las certificaciones, débil representación de los productores en las organizaciones que deciden los criterios para otorgar las certificaciones de comercio justo, bajo nivel de conocimiento de los ciudadanos sobre las principios y actividades del comercio justo, falta de recursos económicos y financieros de los productores, entre otros. Conclusiones. El acceso al esquema del comercio justo es más fácil para organizaciones de productores grandes, con mayor experiencia en temas como la exportación, con estructuras organizacional maduras, por poner unos pocos ejemplos, lo cual causa que pequeños productores sean cada vez más marginalizados. Sin embargo, el comercio justo bien aplicado es, sin duda, una ventajosa herramienta para el desarrollo sustentable.
Legacies of Love, Peace and Hope: How Bioethics Education can Overcome Hatred and Divide
Authors: Macer Darryl R.J. 
Published: January 2021

In our pursuit of a good life (eubios), both individuals and societies, need to educate themselves on the pursuit of love of life in all domains, self-love, love of others, loving good and love of life. In this paper I reflect on my own journey through growing up in Christchurch, and experiences around the world, that are the basis for that conclusion. In our efforts to pursuit bioethics education we can enhance peaceful and harmonius coexistence in our world, through nurturing good decisions that we should all make.
Kajian Potensi Sumber Daya Perikanan di Kecamatan Ampenan Kota Mataram Provinsi Nusa Tenggara Barat
Authors: Wilandari Saponi , Sinaga Walson Halomoan , Nuraini Yenni 
Published: January 2021

Kota Mataram merupakan salah satu kota yang ada di Nusa Tenggara Barat yang memiliki potensi perikanan dalam sektor budidaya, pengolahan, dan penangkapan. Kajian Potensi Sumber Daya Perikanan di Kecamatan Ampenan Kota Mataram merupakan salah satu langkah awal untuk menggali data dan informasi untuk menentukan bahan dan metode penyuluhan yang sesuai dengan kebutuhan guna mendorong percepatan pembangunan di sektor perikanan khususnya dan pembangunan nasional pada umumnya. Tujuan penelitian ini adalah mengkaji potensi SDA, SDM perikanan dan sosial perikanan di Kecamatan Ampenan, Kota Mataram, Provinsi Nusa Tenggara Barat. Alat yang digunakan dalam pengambilan data adalah borang dan kuisioner dengan materi kondisi umum Kecamatan Ampenan, kondisi umum sumber daya manusia, kondisi potensi sumber daya penunjang, dan kondisi perikanan. Data dikumpulkan dengan menggunakan metode wawancara dan metode observasi. Kecamatan Ampenan memiliki potensi perikanan mulai dari simber daya alam, sumber daya manusia, dan sumber daya penunjang. Permodalan pelaku usaha berasal dari modal sendiri. Rumah tangga perikanan (RTP) berjumlah 1.114 RTP dan sekitar 79,1% dari jumlah RTP yang ada berusaha dibidang penangkapan ikan (nelayan). Kelompok perikanan yang terbentuk sebanyak 54 kelompok.
Obesidade na adolescência: um perfil traçado atualmente através de revisão narrativa
Authors: Nascimento Maciel Borges do , Porto Murilo de Jesus , Souza Jaciara Pinheiro de , Guerra Maria de Fátima Santana de Souza , Araujo Ana Mara Borges , Andrade Walber Barbosa de , Santana Welde Natan Borges de , Santos Gilvania Piedade , Santana Antero Fontes de , Silva Sandra Regina Santana 
Published: January 2021

A obesidade consiste em uma condição clínica caracterizada pelo acúmulo excessivo de gordura no organismo, considerada uma doença genética multifatorial, agravadas por fatores ambientais, psicológicas, culturais, hereditários, alimentares, hormonais e metabólicos. A presente pesquisa tem como objetivo discutir sobre a obesidade na adolescência em período escolar através de uma revisão literatura. Como processo metodológico, tratra-se de um estudo de revisão narrativa simples. A coleta de dados para a realização deste estudo foi feito a partir de um levantamento bibliográfico através de busca eletrônica de artigos indexados no Scielo, Google Acadêmico, Lilacs, sites confiáveis, manuais do Ministério da Saúde. Como resutados apresentados, pode-se notar que, nos últimos anos, houve um grande número de casos de obesidade na infância e na adolescência. Várias pesquisas apontam que este crescimento repentino da obesidade pode estar associado com diversos fatores contribuintes como: maus hábitos alimentares, sedentarismo, fatores genéticos, nível socioeconômico e fatores emocionais. Estudos mostram que fatores genéticos têm grande influência no aumento da obesidade, sendo ela uma doença complexa e heterogênea. É importante ressaltar que fatores genéticos por si só não explicam o ganho de peso. Dessarte, a combinação de genes com os fatores supramencionados estão envolvidos no desenvolvimento das formas mais comuns da obesidade. Vários tratamentos foram mencionados durante essa revisão, sendo que a atividade física na adolescência juntamente com a MEV têm seu papel fundamental no tratamento e prevenção da obesidade.
EFEKTIFITAS PERASAN DAUN SIRIH HIJAU ( PIPER BETLE L.) SEBAGAI INSEKTISIDA ALAMI TERHADAP MORTALITAS BELALANG HIJAU (OXYA SERVILLE)
Authors: Rahmawati Anita 
Published: January 2021

Tanaman sirih merupakan tanaman hijau yang merambat dengan daun yang berbentuk hati. Tanaman dari keluarga PiperaceaeIni berasal dari Asia Selatan (India, Nepal, Bangladesh, Sri Langka) serta tumbuh luas di kawasan malaysia dan Indonesia.Tanaman ini potensial untuk di budidayakan karena dapat di gunakan sebagai anti septik dan obat luka.Tanaman ini tidak dipercaya efektif untuk mengobati berbagai penyakit, Salah satu contoh yaitu karies gigi.Dalam studi farmakologi, daun sirih hijau dapat digunakan sebagai obat analgesik, anti bisul, anti alergi, anti bakteri, anti jentik nyamuk, anti oksidan, dan anti serangga serta anti diabetes.Dalam penelitian ini perasan daun sirih hijau ditumbuk halus denan dosis 35ml, 45ml, dan 55ml. Desain penelitian menggunakan rancangan acak lengkp (RAL) dengan 3 perlakuan dan 3 kali pengulangan.
Berdasarkan hasil uji dan dapat diketahui bahwa hasil Asymp.Sig adalah 0,258> 0,05 dapat diartikan bahwa secara stastistik Ho diterima dan Ha ditolak. Data tersebut diperoleh dari hasil uji anova terhadap tiga kali perlakuan dan tiga kali pengulangan selama 12 jam dengan dosis yaitu 35 ml, 45 ml, dan 55 ml. Setelah data diuji menggunakan anova hasilnya tidak signifikan dan tidak perlu menggunakan uji lanjut.
Historia de la Escuela de Salud Pública del Perú (1964-1985). Antecedentes, desarrollo y comentarios.
Authors: Morales-Soto Nelson Raúl 
Published: January 2021

En la Presentación el Dr. Manuel Alberto Díaz de los Santos, Director General de Personal de Salud, Ministerio de Salud, apunta: “El libro que presentamos, es el resultado de la sistematización de aspectos históricos fundamentales del país y del extranjero para contextualizar el origen y procesos históricos de la Escuela; utilizando imágenes y relatos que entrelazan el proceso pasado-presente y perspectiva de futuro; alguno de estos materiales han sido recopilados de archivos históricos, fotográficos y publicaciones de la época. La obra tiene una estructura formal basada en capítulos y sub-capítulos, que son escenarios analizados de las etapas históricas de reconstrucción de la Escuela de Salud Pública del Perú y de cómo responde el Estado en los diversos períodos a la progresiva expansión de los servicios de salud y a la necesidad de formación y capacitación en salud pública. Igualmente, los autores comparten el interés de entender la salud pública peruana a partir de la historia de la Escuela de Salud Pública del Perú, logros y tensiones de cada período y las posibilidades y desafíos que ofrecen para el futuro de la salud pública peruana”.
The Effect of Magnesium on Reperfusion Arrhythmias in STEMI Patients, Treated With PPCI. A Systematic Review With a Meta-Analysis and Trial Sequential Analysis
Authors: Szapary Laszlo B. , Szakacs Zsolt , Farkas Nelli , Schonfeld Kristof , Babocsay Dora , Gajer Mate , Kittka Balint , Magyari Balazs , Hegyi Peter , Szokodi Istvan , Horvath Ivan G. 
Published: January 2021

Aims: The restoration of coronary circulation plays a crucial role in treating ST-segment elevation myocardial infarction (STEMI), however successful reperfusion with primary percutaneous coronary intervention (PPCI) may induce life-threatening arrhythmias. The relation between myocardial electrical instability, as a background factor in reperfusion arrhythmia, and magnesium administered periprocedurally is still questionable. Several randomized clinical trials have been conducted predominantly in the thrombolysis era. Due to the contradictory results of these studies, there is little evidence of the potential preventive effect of magnesium on reperfusion arrhythmias. The aim of our study is to review and meta-analytically analyze data from all studies published so far in the PPCI era, comparing STEMI patients who have undergone primary PCI and received either magnesium or a placebo before the reperfusion procedure.Methods and Results: Our meta-analysis follows the points in the PRISMA protocol and, meets all of their criteria. We conducted a search in five scientific databases using the following keyword combination: (myocardial infarction OR myocardial injury OR acute coronary syndrome OR acs OR stemi) AND magnesium. The 7,295 collected publications were filtered with the Endnote program by title, abstract and full-text based on predefined criteria. A statistical analysis was performed on three randomized-controlled trials using three common parameters, involving 336 patients Trial sequential analysis (TSA) was applied to assess the risk of random error associated with sparse data and multiple testing which can affect cumulative meta-analysis. The incidence of ventricular tachycardias (VTs) was not significantly increased in the non-magnesium control group. (OR: 1.36; CI: 0.619; −2.986, P = 0.263). For the ejection fraction (EF), a non-significant decrease was observed in the magnesium group by weighted mean difference calculation. (WMD: 7.262, 95% CI: −0.238; 0.053; P = 0.057). There was significant decrease in the infarct zone wall motion index (IZWMSI) in the magnesium treatment group. (WMD: 0.384, 95% CI: −0.042; 0.811, P = 0.015). Based on the TSA assessments, the results of all parameters are not significant, objectively demonstrating the lack of reasonable data pertaining to our question.Conclusions: The preventive effect of magnesium on reperfusion arrhythmia associated with primary PCI can still be considered contradictory based on previous studies. In our study, we found, that magnesium is ineffective with a very weak evidence, due to the small number of patients and the biases of the included studies, and a well-designed clinical trial is needed in this area, based on the TSA.
Age-Specific Imbalance of Circulating Tfh Cell Subsets and Its Association With Gout-Targeted Kidney Impairment
Authors: Huang Yefei , Wu Xinyu , Gui Lian , Jiang Yutong , Tu Liudan , Li Xiaomin , Jiang Boxiong , Wang Yina , Zheng Xuqi , Wei Qiujing , Li Qiuxia , Ou Jiayong , Chen Zena , Xie Ya , Lin Zhiming , Liao Zetao , Fang Linkai , Qiu Minli , Cao Shuangyan , Gu Jieruo 
Published: January 2021

ObjectiveGout is a chronic disease characterized by the deposition of monosodium urate (MSU) crystals in tissue. Study with a focus on adaptive immune response remains to be understood although innate immune response has been reported extensively in gout etiology. Our study attempted to investigate the association of gout-related immune cell imbalance with clinical features and comorbidity with renal impairment and the implicated pathogenesis via the assessment of T and B cell subsets in different activity phases or with immune effects combined with the analyses of clinical parameters.MethodsFifty-eight gout patients and 56 age- and sex-matched healthy individuals were enrolled. To learn the roles of circulating T cells, a lymphocyte profile incorporating 32 T cell subsets was tested from isolated freshly peripheral blood monocyte cells (PBMCs) with multiple-color flow cytometry. Furthermore, the collected clinical features of participants were used to analyze the characteristics of these differential cell subsets. Stratified on the basis of the level of creatinine (Cr, enzymatic method), all patients were categorized into Crlow (Cr ≤ 116 μmol/L) and Crhi (Cr &gt; 116 μmol/L) groups to exploit whether these gout-associated T cell subsets were functional in gout-targeted kidney dysfunction. The differentiation of B cells was investigated in gout patients.ResultsOur results show that CD 4+ T cells, Th2 cells, and Tc2 cells were upregulated, whereas Tc17 cells were downregulated. Tfh cells skewed toward the polarization of Tfh2 cells. Specifically, Tfh2 cells increased, but Tfh1 cells decreased, accompanied with aging for gout patients, suggesting that age might trigger the skewing of Tfh1/Tfh2 cell subsets to influence gout development. Moreover, Tfh2 cells were connected to renal dysfunction as well. No alterations of B cell subsets were observed in patients when compared to controls.ConclusionsOur data demonstrate age-specific dysfunctions of Tfh1/2 cells in gout occurrence, and Tfh2 cell upregulation is associated with gout-targeted renal dysfunction. However, Tfh2 cells may function in auto-inflammatory gout independent of helping B differentiation, and an in-depth study remains to be conducted.
Evaluation of Wearable Technology in Dementia: A Systematic Review and Meta-Analysis
Authors: Cote Alanna C. , Phelps Riley J. , Kabiri Nina Shaafi , Bhangu Jaspreet S. , Thomas Kevin “Kip” 
Published: January 2021

Background: The objective of this analysis was to systematically review studies employing wearable technology in patients with dementia by quantifying differences in digitally captured physiological endpoints.Methods: This systematic review and meta-analysis was based on web searches of Cochrane Database, PsycInfo, Pubmed, Embase, and IEEE between October 25–31st, 2017. Observational studies providing physiological data measured by wearable technology on participants with dementia with a mean age ≥50. Data were extracted according to PRISMA guidelines and methodological quality assessed independently using Downs and Black criteria. Standardized mean differences between cases and controls were estimated using random-effects models.Results: Forty-eight studies from 18,456 screened abstracts (Dementia: n = 2,516, Control: n = 1,224) met inclusion criteria for the systematic review. Nineteen of these studies were included in one or multiple meta-analyses (Dementia: n = 617, Control: n = 406). Participants with dementia demonstrated lower levels of daily activity (standardized mean difference (SMD), −1.60; 95% CI, −2.66 to −0.55), decreased sleep efficiency (SMD, −0.52; 95% CI, −0.89 to −0.16), and greater intradaily circadian variability (SMD, 0.46; 95% CI, 0.27 to 0.65) than controls, among other measures. Statistical between-study heterogeneity was observed, possibly due to variation in testing duration, device type or patient setting.Conclusions and Relevance: Digitally captured data using wearable devices revealed that adults with dementia were less active, demonstrated increased fragmentation of their sleep-wake cycle and a loss of typical diurnal variation in circadian rhythm as compared to controls.