bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multiparametric MRI assessment of response to convection-enhanced intratumoral delivery of MDNA55, an interleukin-4 receptor targeted immunotherapy, for recurrent glioblastoma
Authors: Mohan Suyash , Wang Sumei , Chawla Sanjeev , Abdullah Kalil , Desai Arati , Maloney Eileen , Brem Steven 
Published: July 2021

Background:
Glioblastoma (GBM) is the most common malignant brain tumor and carries a dismal prognosis. Attempts to develop biologically targeted therapies are challenging as the blood–brain barrier can limit drugs from reaching their target when administered through conventional (intravenous or oral) routes. Furthermore, systemic toxicity of drugs often limits their therapeutic potential. To circumvent these problems, convection-enhanced delivery (CED) provides direct, targeted, intralesional therapy with a secondary objective to alter the tumor microenvironment from an immunologically “cold” (nonresponsive) to an “inflamed” (immunoresponsive) tumor.

Case Description:
We report a patient with right occipital recurrent GBM harboring poor prognostic genotypes who was treated with MRI-guided CED of a fusion protein MDNA55 (a targeted toxin directed toward the interleukin-4 receptor). The patient underwent serial anatomical, diffusion, and perfusion MRI scans before initiation of targeted therapy and at 1, 3-month posttherapy. Increased mean diffusivity along with decreased fractional anisotropy and maximum relative cerebral blood volume was noted at follow-up periods relative to baseline.

Conclusion:
Our findings suggest that diffusion and perfusion MRI techniques may be useful in evaluating early response to CED of MDNA55 in recurrent GBM patients.
مدى الحاجة الى المعرفة العلمية لدى طلبة جامعة دهوك وعلاقتها ببعض المتغيرات
Authors: Sediq Siyar 
Published: July 2021

يهدف البحث الى تعرف مدى الحاجة الى المعرفة العلمية لدى طلبة جامعة دهوك وعلاقتها ببعض المتغيرات من وجهة نظرهم، تكونت عينة البحث من كليتي العلوم والادارة والاقتصاد في جامعة دهوك اذ بلغت(280) طالباً وطالبةً بواقع (135) طالباً وطالبةً من كلية العلوم و(145) طالباً وطالبةً من كلية الادارة والاقتصاد، ولتحقيق أهدافه أعد الباحث أداةً خاصة بتطبيق مدى الحاجة للمعرفة العلمية، حيث تكونت في صورتها النهائية من(32) فقرة، استخدام الباحث معامل ارتباط بيرسون، والمتوسط الحسابي والانحراف المعياري، واختبار (z-test)، توصل الى مايلي:
1- بلغت نسبة فقرات الاستبانة عند طلبة كلية العلوم للحاجة المعرفية العلمية عند الطلاب (%61.93) وعند الاناث (%64.23) وهي نسبة متوسطة .
2- بلغت نسبة فقرات الاستبانة عند طلبة كلية الادارة والاقتصاد للحاجة المعرفية العلمية عند الطلاب (%59.2) وعند الاناث (%61.82) وهي نسبة متوسطة.
3- لا توجد فروق ذات دلالة إحصائية بين درجات وجهتي نظر افراد عينة البحث في كليتي (العلوم، والادارة والاقتصاد) في الحاجة الى المعرفة العلمية.
4- لا توجد فروق ذات دلالة إحصائية بين درجات وجهتي نظر افراد عينة البحث من الطلاب (الذكور) في كليتي (العلوم، والادارة والاقتصاد) في الحاجة الى المعرفة العلمية.
5- لا توجد فروق ذات دلالة إحصائية بين درجات وجهتي نظر افراد عينة البحث من الطالبات (الاناث) في كليتي (العلوم، والادارة والاقتصاد) في الحاجة الى المعرفة العلمية.
Ahmet Haşim᾿in Şiirlerinde Farsça Unsurlar
Authors: Abbas Faik , Mohammed Jumaa 
Published: July 2021

Kültürel değerlerin en güçlü ve sağlıklı paylaşımı, kuşkusuz dil aracılığıyla gerçekleşmektedir. Dil olgusu, diğer olgular gibi dinamik bir yapıya sahip olarak her zaman başka diller ve siyasal-toplumsal değişimlerden etkilenmiştir. Bu çalışmada milli dili kendilerine has bir özellikte kullandıkları 20. yüzyılın Türk şiirinde önemli bir isim olan Ahmet Haşim’in tüm şiirlerinde kullanılan Farsça unsurlara dair bir deneme yaptık. Çalışmada Ahmet Haşim’in bütün şiirlerinde kaç unsur türü kullanılmıştır. Kullanılan unsurların tekrar sıklığı ne durumdadır, en çok ve en az kullanılmış unsurlar hangileridir, fiil çeşitleri , isim ve türleri hangi sıklıkta kullanılmıştır. Ön ekler, son ekler, birleşik isim, birleşik sıfat, isim tamlaması, sıfat tamlaması, zarf, ünlem edatları gibi kullanılan Farsça unsurları tek tek ele alınmaktadır. Haşim’in şiirinde geçtikleri unsurları manaları dikkate alınarak izahat verilmiştir. Böylece Haşim’in fikir ve sanat dünyasına dair ipuçlarına ulaşılarak, kullandığı Farsça unsurlarla Türkçeyi zenginleştirmiştir.
Арктичний регіон у зовнішній політиці США за адміністрації Д. Трампа
Authors: Bohdanova Tetiana , Cherevko Anna 
Published: July 2021

У статті проаналізовано Арктичний регіон у зовнішній політиці США за адміністрації Д. Трампа. Охарактеризовано нормативно-правову базу арктичної політики Д. Трампа, яка була оновлена у 2019-2020 рр. Виявлено, що зовнішньополітичні ініціативи Д. Трампа на арктичному напрямі орієнтовані на такі сфери: 1) військово-оборонна та мілітаризація Арктики (протидія Росії та Китаю, а також залучення до Арктики НАТО); 2) енергетична (зняття мораторію на видобуток нафти і газу на Алясці). Автори дійшли висновку, що політика США за президентства Д. Трампа відрізняється від політики Б. Обами та є більш жорсткою.
SISTEM MONITORING DAN KONTROL TANAMAN KOPI UNTUK SMART GREENHOUSE MENGGUNAKAN WIRELESS SENSOR NETWORK BERBASIS INTERNET OF THINGS
Authors: Fibriani Ike , Widjonarko Widjonarko 
Published: July 2021

Wireless yang telah ada dan banyak digunakan. Seperti salah satu contoh yaitu Wireless Sensor Network. Keunggulan dari penggunakan teknologi WSN yaitu data yang diperoleh dapat terkirim secara cepat dan efisien, serta informasi dapat terpantau secara langsung atau real time. ZigBee digunakan sebagai protokol untuk sistem Wireless Sensor Network ini, dimana penerapan ini digunakan sebagai Smart Greenhouse. Menggunakan 2 buah node yang dipasangkan 3 buah sensor, yaitu sensor DHT 11,YL-69 dan LDR dan 1 buah coordinator yang bertugas sebagai penerima data sensor dari kedua node dan melakukan upload pada web. Pada penelitian ini parameter yang digunakan yaitu RSSI dan daya sinyal. Pengujian RSSI dan daya menggunakan kondisi LOS dengan jarak 100 meter sampai 1000 meter dan NLOS dengan jarak 10 meter sampai 100 meter. Hasil dari pengujian RSSI pada kondisi NLOS didapatkan nilai tertinggi sebesar -56 dBm pada node 1 pada jarak 10 meter dan pada node 2 nilai tertinggi yaitu sebesar -57 dBm pada jarak 10 meter. Hasil dari pengujian packet loss pada kondisi NLOS node 1 dan node 2 didapatkan hasil yaitu 0%. hasil pengujian pada kedua kondisi dan jarak yang berbeda, secara garis hasilnya sama. pada kondisi jarak yang semakin jauh, nilai RSSI semakin kecil.
Circular Polarization of the Square, Circular, Triangle, and Hexagonal Microstrip Antenna
Authors: Nurhayati Nurhayati , Lutfia Paulen Aulia , Sobrinho Raimundo Eider Figueredo , De Oliveira Alexandre Manicoba , Filho JoÃ£o Francisco Justo , Fukusako Takeshi 
Published: July 2021

Microstrip antenna with circular polarization can be applied for many applications. Some microstrip antenna with square, circular, triangular, and hexagonal shape has been designed to get return loss, axial ratio, and radiation performance. We compare twelve microstrip antenna by maintaining its substrate dimension, feeding shape, and outer patch dimension. Even though antenna has a circular patch, it doesnt always produce circular polarization. From the simulation, we found that with add some structure, the antenna can reach multiband resonance from 1 to 6 GHz. The Circular patch antenna reached seven numbers of the multiband resonance frequency. The hexagonal patch antenna reaches the highest directivity as 9.53 dBi. The circular polarization is achieved for a square and Hexagonal patch shape with axial ratio value is 1.96 dB at 4 GHz and 1.26 dB at 4.1 GHz sequentially at phi 900 and theta 900.
Evaluación de una intervención cognitiva para los síntomas coronarios en la mujer: ensayo clínico no aleatorizado
Authors: Motta León Claudia Patricia 
Published: July 2021

El presente artículo tiene como objetivo determinar la eficacia de una estrategia de manejo cognitivo de los síntomas de enfermedad coronaria para mejorar las acciones de respuesta y los niveles de autoeficacia general en un grupo de mujeres participantes de un programa de rehabilitación cardiaca en dos instituciones de salud de la ciudad de Bogotá D.C.
La metodología utilizada fue un diseño tipo ensayo clínico controlado no aleatorizado. La intervención se realizó en cuatro sesiones con un encuentro semanal. Las acciones de respuesta y los niveles de autoeficacia fueron evaluados al inicio, dos y cinco semanas después de finalizar la intervención.
El análisis de resultados mostró una correlación positiva en el grupo experimental entre las acciones de respuesta y los niveles de autoeficacia general que se mantiene en la medición intermedia y final. Respecto a la autoeficacia la intervención no demostró mayor eficacia que la intervención convencional. Lo anterior comprueba la importancia de incluir elementos cognitivos y enfoque de género dentro de los programas de rehabilitación cardíaca.
Pendidikan Keuangan Keluarga, Kesadaran Keuangan dan Tingkat Personal Finance
Authors: Pahlevi Reza Widhar , Nashrullah Lazzuardi 
Published: July 2021

The purpose of this study was to determine the effect of financial education on the family, financial education on campus, peers, financial literacy and financial awareness on the level of student personal finance. The sampling technique uses a non probability sampling technique. While the sampling method uses incidental sampling, whoever by chance or fits as a data source, then continues using the purposive sampling method, namely the sam-pling technique with the consideration of students of the Faculty of Economics in Yogya-karta who have taken Financial Management courses and who have taken courses that concentrate on Finance. From these considerations, 103 respondents. The data analysis technique uses multiple regression analysis. The results showed that financial education in the family, financial literacy and financial awareness had a significant effect on student personal finance, while financial education on campus and peers had no effect on student personal finance. DOI: https://doi.org/10.26905/afr.v3i2.5840
Stability and Deformation Analysis of Landslide under Coupling Effect of Rainfall and Reservoir Drawdown
Authors: Shoaib Muhammad , Yang Wang , Liang Yang , Rehman Gohar 
Published: July 2021

Landslides, a devastating hazard, continue to happen, affecting the lives of thousands of people each year. Fluctuation in the Reservoir Water Level (FRWL) is one of the leading features disturbing the slope stability in reservoir areas, drawdown is more crucial than the rise to the stability of landslide. Latest studies grounded on field investigation and monitoring data propose that landslides in reservoir areas are initiated not solely by one issue like precipitation or FRWL, however conjointly by their joint actions. Zhulinwan landslide in Chongqing, China, Three Gorges Reservoir (TGR) area was analyzed by field investigation and numerical modelling to evaluate the characteristics of the landslide. The changes in landslide stability and deformation under the effect of reservoir drawdown and rainfall is analyzed using GEOSLOPE Software. The seepage analysis is done using SEEP W Model, afterward deformation and stability analysis using SLOPE W and SIGMA W respectively. The analysis confirmed that the coupling effect of reservoir drawdown at 1.2 m/d and rainstorm of once in 50 years return period makes the landslide unstable. Moreover, deformation at the same condition is maximum 0.049 m. The findings may be used by local authorities to help make decisions about slope stabilization in the event of a confirmed significant rainfall event. Doi: 10.28991/cej-2021-03091713 Full Text: PDF
Comparative Analytical Study on Crack Width of Reinforced Concrete Structures
Authors: Abu El Naas Ahmed A. , El Hashimy Hany M. , El Kashif Khaled F. 
Published: July 2021

This paper presents a comparative study for the cracking limit state according to design codes. It aims mainly to connect research findings with design code equations. Appropriate recommendations are reached and the various factors and parameters influencing crack width investigated. The most appropriate equation for crack width calculation can be found. This is done by creating an analytical and numerical program studied various factors and parameters affecting on the crack width. The Analytical study includes some variables affecting the crack width such as steel stress, concrete cover, flexural reinforcement ratio and rebar arrangement. A 3-D finite element analysis by ABAQUS were used to model and idealize the problem. The numerical results were compared with the analytical results. It was concluded that some codes did not take into account the impact of some major variables and cases on the crack width. Also, it was found that some codes are not clear in the region concerning the position of the crack width calculation and the values obtained for the crack width. For calculating crack width values, JSCE (2007) equation is the most appropriate equation as it takes into account the main parameters that affect crack width. Doi: 10.28991/cej-2021-03091720 Full Text: PDF
Optimizing Mixtures of Alkali Aluminosilicate Cement Based on Ternary By-Products
Authors: Long Hoang Vinh 
Published: July 2021

Portland cement is a popular binder but causes many adverse effects on the environment. That is due to the large consumption of raw materials and energy during production while emitting vast amounts of CO2. In recent years, Alkali Aluminosilicate Cement (AAC) has drawn much attention in research and development and promises to become a binder that can replace the traditional cement. In many studies of this binder, the content of the ingredients is often gradually changed to determine the optimal composition. The object of this paper is to optimize the composition of AAC using a combination of three by-products as the primary raw material, including Rush Husk Ash (RHA), Fly Ash (FA), and Ground Granulated Blast-Furnace Slag (GGBS). The investigation was conducted based on the critical parameter SiO2/Al2O3, and the D-optimal design. The FA and the GGBS were industrial product form, while the RHA was ground in a ball mill for 2 hours before mixing. The results show that this type of binder has setting time and soundness to meet standard cement requirements. While comparing to Portland cement, the AAC has a faster setting time, slower development of compressive strength in the early stages but a higher strength at the age of 56 days. According to the highest compressive strength at 28 days and high fly ash content, the optimal composition was RHA of 27.8%, FA of 41.8%, and GGBS of 15.4%, corresponding to the ratio SiO2/Al2O3 of 3.83. In addition, compressive strength at 28 days of the mortar specimens with the optimal binder and the ratio of water/ cement at 0.32 reached 63 MPa. Doi: 10.28991/cej-2021-03091724 Full Text: PDF
Who Was John Sampson Really Protecting?
Authors: Roberts Reilly Frances 
Published: July 2021

Begun in 1888, the Gypsy Lore Society (GLS) set out to describe and preserve Welsh Kale Romani customs, culture and language. Leaders in this effort were John Sampson, Francis Hindes Groome and Dora Yates, among others who took on the role of ethnographers, anthropologists and linguists. This paper raises the question, “Who Was John Sampson Really Protecting?” It is answered through an extensive examination of documented sources: birth records, census records, newspaper articles, Gypsy Lore Society Journals, academics on racism, and modern-day ethnography and anthropological practices. As well as family history; the archived memory of a Wood family member. It is premised on these facts – that John Sampson’s ethics, methods and emotional investment ignores the context and inhumane impact of his study, namely the everyday lives and voices of his subject matter. His goal was heavily influenced by the works of Charles Darwin and intellectualbaggage of the history of the world seen through British eyes; simply as a straight line from cultures to possess the deep roots of civilization itself. The purer and more hidden the better. The method used by John Sampson was to capture as much of the Welsh Kale culture and language by embedding himself in one family – the Wood family who he proclaimed spoke the “pure” Romanus language of the Abram Wood tribe of North Wales. His published work on this is The Dialect of the Gypsies of Wales: Being the Older Form of British Romani Preserved in the Speech of the Clan of Abram Wood” (1926). Against this intellectual stronghold fortressed inside a racially superior monolith, the story of Edward Wood, John Roberts and their extended family is told. Ethically however, his project also raises serious questions about the dichotomy of singling out the Wood family from others who also spoke Welsh Kale Romanus but were excluded from John Sampson’s studies. He and the GLS recast the Wood family in romantic Victorian terms to use as props with which to stage their inventions in widely published articles to a gullible audience. In this paper, the moral position taken is one of noncompliance with the Romanized recasting and politicizing of the “Pure” Gypsy that local authorities used as policy to rationalize the separation of families and force them into housing right up to the 1970s. What is called today, “Scientific Racism”. Concluding with the ways we are dealing with the intergenerational trauma and the collateral damage done to these Welsh Kale families. Asserting, our own voices and legacy have earned us a rightful place in the wider collective as we commit to standing together in our ethnicity, diversity, and authenticity with all Roma.
The Legality of Nadzir Waqf Land Managerin Islamic Philanthropy Studies (A Case Study in Tampan, Pekanbaru City)
Authors: Andriko Andriko , Offiyardi Offiyardi 
Published: July 2021

Purpose: This research aims to find out the legality of nadzir as the manager of the waqf lands in Islamic philanthropy perspective of it.Design/Method/Approach: The report on the replacement and dismissal of nadzir to the office of religious affairs of Tampan is not properly performed; thus of the 212 population, the writer takes 5 nadzirs as a sample analysed descriptive qualitative analysis with purposive sampling technique.Findings: The research shows that none of nadzir reports the replacement and dismissal to the local office of religious affairs (KUA). The nadzirs only know that waqifs hand waqf land over to them to be used by muslim, but not for the matter of the replacement and dismissal. In other words, nadzirs in Tampan have not developed a professional sense of duty due to the lack of socialization from KUA.Originality/Values: Furthermore, the impact of no report on retiring and shifted nadzir to KUA is mudharat in the system of administrations or report on waqf land. At worst, misuse of waqf land can occur. The report on the replacement and dismissal of nadzir in Tampan is inconsistent with article 221 of Law Number 41 of 2004. Verse 1 and 2 state that nadzir is obliged to report the replacement and dismissal of nadzir to local KUA.
ZIS (Zakat, Infaq And Alms) Funds Management Methods In Improving The Quality Of Mustahiq Life In BAZNAS Karanganyar
Authors: Rizki Darlin 
Published: July 2021

Purpose: This study aims to analyze the role of philanthropy (ZIS) in reducing poverty and improving the quality of life in the Karanganyar society district.Method: This type of research is field research using a qualitative descriptive approach and applying an intrinsic case study model. The research data was obtained from the annual report of BAZNAS Karanganyar, interviews, and field observations as well as literature study conducted as secondary data.Findings: The results of this study found that ZIS can solve various problems and contribute to improving the quality of life of the Karanganyar community. Through the collaboration of BAZNAS with the city government, there are more than 600 UPZs scattered to collect zakat in government agencies, private companies, and the community. ZIS is realized in 5 flagship programs of BAZNAS Karanganyar, which can encourage productivity (being) and simultaneously increase mustahik's participation in their environment, such as family, social, workplace, school, and so on. And mustahik have hope and optimism to improve the quality of life (becoming).Originality/Values: Provide information to the public how ZIS management methods in BAZNAS Karanganyar, relationships with the city government, and the synergy of BAZNAS programs to improve the quality of mustahik.life
Exploring national COVID-19 variability across sub-Saharan Africa
Authors: Amahazion Fikresus 
Published: July 2021

Background In early March 2020, coronavirus disease (COVID-19), an infectious disease caused by a novel coronavirus, was declared a pandemic by the World Health Organization. Since its emergence and global spread, the pandemic has been one of the greatest global crises in modern human history. Notably, in Sub-Saharan Africa (SSA), COVID-19-related burden and outcomes have been generally lower than many other parts of the world and substantially better than were initially feared. At the same time, there has been great heterogeneity in COVID-19 burden and outcomes between countries in the region, with some reporting particularly high incidence and death figures compared to others. What accounts for the significant cross-country variability apparent in SSA and why have some countries performed better than others? The present study investigates country-specific factors that may help to explain differences in COVID-19 outcomes across 48 countries in SSA. Methods A novel cross-sectional dataset, comprising a wide array of socio-demographic, political, economic, and health-related variables, is constructed through gathering data from publicly available sources. Descriptive statistics, correlation analyses, and multiple regression analyses are performed to reveal important country-level factors associated with COVID-19 deaths in SSA. Results Findings from statistical analyses show that in SSA COVID-19 deaths per million is positively associated with income inequality and median age, and negatively associated with population density. In contrast, a number of other variables, including gross national income (GNI) per capita, global connectivity, diphtheria, tetanus and pertussis (DTP) immunization coverage, the proportion of seats in parliament held by women, and political system or regime type, are not statistically significant. Conclusions Although findings from recent studies conducted in various settings around the world indicate that a range of socio-economic, demographic, political, and health-related factors may be linked with COVID-19 burden, the present investigation finds that COVID-19 deaths in SSA are associated with population density, median age, and income inequality.