bluuebunny/crossref_metadata_2025_split huggingface dataset:
How information technology capability influences organizational agility: empirical evidences from Indian banking industry
Authors: Panda Sukanya , Rath Santanu Kumar 
Published: October 2021

PurposeThe purpose of this paper is to highlight a precise investigation of the relationship between information technology (IT) capability and organizational agility along with the moderating impact of environmental factors on this association.Design/methodology/approachPre-tested structured questionnaires were administered during a matched-pair field survey to collect primary responses from 300 business and IT personnel working in various public and privately owned banking groups functioning in India. The structural equation modeling approach has been used for data analysis.FindingsThe two-folded research findings are first, IT capability enables organizational agility (studied as business process and market responsive agility), while IT capability has more effect on market responsive agility. Second, the environmental factors (studied as environmental diversity and hostility) possess a significant effect on the IT-agility relationship and, thereby, suggest that a more diverse and less hostile environment is required for the firms to build up superior IT capability for realizing enhanced agility.Originality/valueThe authors have studied IT capability as a first-order factor, organizational agility and environmental factors as second-order factors and by meticulously examining their critical dimensions this study greatly contributes to the existing IT-agility literature. The derived inferences provide various implications for the bank and IT managers to emphasize on superior IT capability for generating enhanced organizational agility.
Mindfulness and study engagement: mediating role of psychological capital and intrinsic motivation
Authors: Ali Muhammad , Khan Ali Nawaz , Khan Mubbsher Munawar , Butt Atif Saleem , Shah Syed Hamad Hassan 
Published: October 2021

PurposeThis study aims to analyze the relationship between mindfulness and study engagement focusing on the mediating mechanism between the relationships proposed. Based on the conservation of resources (COR) theory, the authors examine whether psychological capital (PsyCap) and intrinsic motivation mediate the relationship between mindfulness traits and study engagement.Design/methodology/approachPath analysis was conducted to test the hypothesized relationships among a sample of 428 international students studying in Chinese universities in Shanghai.FindingsThe results support the hypothesized relationships and imply that mindfulness is an essential antecedent of study engagement and more mindful students are more engaged in studying. Besides, the relationship between self-rated mindfulness and study engagement is mediated by PsyCap and intrinsic motivation.Research limitations/implicationsFor universities, these findings help develop unique educational strategies to resolve issues related to study involvement. The study has several theoretical and practical implications.Originality/valueThe current study explored the relationship between mindfulness and study engagement in international students studying in Chinese universities – an understudied context in higher education. The authors find that mindfulness has positive effects on study engagement through PsyCap and intrinsic motivation.
Optimization of structural parameters for the sound absorption performance of a cellular ceramic foam
Authors: Sun J.X. , Liu P.S. 
Published: October 2021

PurposeThe purpose of this paper is to provide an optimization schedule of structural parameters for the sound absorption performance of a cellular ceramic foam in the sound frequency range of 200–4,000 Hz.Design/methodology/approachThe cellular ceramic foam with porosity of about 60–75% and the pore size of about 1–7 mm was successfully prepared by using natural zeolite powder as the main raw material. For this ceramic foam, the sound absorption performance was measured, and the absorption structure was optimized by some important structural parameters. With orthogonal experiment, optimization of structural parameters was found for absorption performance. By means of the range analysis method, the main factor is known to influence the performance of ceramic foam.FindingsThe present ceramic foam may have good absorption performance although at relatively low frequencies of 400–4,000 Hz while structural parameters of sample are appropriately combined. With orthogonal experiment, optimization of structural parameters for the absorption performance was found to be as follows: sample thickness, 25 mm; porosity, 73.5%; pore size, 4–5 mm and air gap depth, 20 mm. To influence the performance, sample thickness is the main factor, air gap depth is the second and both of pore size and porosity would have a relatively slight effect.Originality/valueThis paper presents a method to optimize the structural parameters of a cellular ceramic foam for sound absorption performance by means of orthogonal experiment.
A molecular classification of moles and its use in filiation tests
Authors: Wenk Robert E. , Peterson John , Baird Michael 
Published: October 2021

AbstractPregnancies, including ones that follow sexual assaults, occasionally produce hydatidiform moles. The alleged fathers (AFs) of moles have been tested for paternity by identifying the mole's locus phenotype—the one or two visible paternal obligate alleles (POAs) per locus. The probability that the mole inherited the POAs from the AF was divided by the probability that the mole inherited the POAs from a random man. This likelihood ratio (LR) would increase if the mole's specific genotype was known. Moles are generated in five different ways that produce five distinct genotypes. Examining a mole's multilocus STR profile reveals a mole's pathogenesis, determines locus genotypes, and increases paternity LRs.
Efficacy of PD‐1/PD‐L1 inhibitors in patients with non‐small cell lung cancer and brain metastases: A real‐world retrospective study in China
Authors: Sheng Jiamin , Li Hui , Yu Xiaoqing , Yu Sizhe , Chen Kaiyan , Pan Guoqiang , Xie Mingying , Li Na , Zhou Zichao , Fan Yun 
Published: October 2021

AbstractBackgroundThere is only limited knowledge of the treatment responses and clinical outcomes of immune checkpoint inhibitors (ICIs) in driver gene‐negative non‐small cell lung cancer (NSCLC) patients with brain metastases (BM). This study aims to assess the efficacy of immunotherapy in these patients in a real world setting.MethodsNSCLC‐BM patients without driver gene mutations who received ICIs were retrospectively identified between July 2017 and December 2019. The primary observation endpoint was intracranial objective response rate (iORR), and secondary objectives were objective response rate (ORR), intracranial and systemic progression‐free survival (iPFS, PFS), and overall survival (OS).ResultsWe reviewed 1578 patients with lung cancer and BM. According to the exclusion criteria, 41 patients were finally enrolled. Among these 41 patients, iORR was 36.6% (95% confidence interval [CI] = 21.2%–52.0%), whereas iPFS was 6.8 (95% CI = 3.32–10.35) months. Additionally, ORR, PFS, and OS were 24.4% (95% CI = 10.7%–38.1%), 6.2 (95% CI = 4.57–7.83) months and 13.7 (95% CI = 11.20–16.26) months, respectively. ICIs combined with concurrent radiotherapy group exhibited preferred iORR (p = 0.030) compared with no radiotherapy group, and ICIs plus chemotherapy showed improved OS (p = 0.024) compared to ICI monotherapy. Moreover, the lines of ICI treatment ≥2 (p = 0.005) and derived neutrophil‐to‐lymphocyte ratio (dNLR) ≥3 (p = 0.010) were independently negative factors for OS.ConclusionIn NSCLC‐BMs patients lacking driver genes, ICIs exhibited an effective drug regime. A combination of ICIs with concurrent radiotherapy showed a better intracranial response, whereas ICIs plus chemotherapy were associated with superior OS.
Fluid administration during routine colonoscopy is not clinically significant: a randomized controlled trial
Authors: Ganguly Timothy , Bierton Christopher , Islam Asif , Chan Lily , Smithers Lisa , Murphy Elizabeth 
Published: October 2021

AbstractBackgroundRetrospective studies have questioned the benefits of intravenous (IV) fluids during routine colonoscopies given they are performed on well patients who experience limited fluid loss, consume clear fluids up until 2 h prior and low IV volumes typically infused. This trial aims to assess the impact of IV fluid on hypotension and electrolyte changes amongst patients undergoing colonoscopy.MethodsParticipants undergoing colonoscopies were randomized (single blinded) to IV fluid or no IV fluid. Primary outcomes were equivalence of intraoperative hypotensive episodes (>20% drop in systolic blood pressure (SBP)) and changes in serum electrolytes post procedure. Secondary outcomes included patient reported outcome measures (PROMs).ResultsOf the 470 participants enrolled, 84/235 (35.7%) from the IV fluids group and 88/230 (38.3%) from the no IV fluids group experienced a hypotensive event (difference in prevalence −2.5, 95% CI −11.3, 6.3). Fourteen participants in each group required clinical intervention to provide haemodynamic support (difference in prevalence −0.1, 95% CI −4.4, 4.2). Postoperative electrolytes changes and PROMs were similar for both groups.ConclusionWhilst definitive recommendations for IV fluid use during routine colonoscopy are not possible as this trial was underpowered to show equivalence between the groups for hypotensive events, there was no clinically meaningful difference between the groups. These findings provide important data for meta‐synthesis and for planning future work.
Simple and reliable method for the application of Seprafilm® during laparoscopic surgery
Authors: Shimizu Hiroki , Kuriu Yoshiaki , Arita Tomohiro , Kiuchi Jun , Yamamoto Yusuke , Konishi Hirotaka , Morimura Ryo , Shiozaki Atsushi , Ikoma Hisashi , Kubota Takeshi , Fujiwara Hitoshi , Okamoto Kazuma , Otsuji Eigo 
Published: October 2021

AbstractIntroductionSeprafilm® has been used to prevent postoperative adhesion. However, it is challenging to insert and apply Seprafilm during laparoscopic surgery because of its fragility and sticky nature caused by moisture. Some studies have reported how to apply Seprafilm into a surgical site during laparoscopic surgery; however, some required special equipment with additional costs, and some were technically difficult to use. Herein, we introduced our simple method for applying Seprafilm during laparoscopic surgery.Material and Surgical TechniqueSeprafilm was cut into three equal rectangle‐shaped pieces and left to absorb moisture for a few minutes. All three pieces of Seprafilm were placed on the gauze, and the gauze was folded in half and grasped by forceps. The gauze with Seprafilm was inserted through a 12‐mm trocar and placed at the surgical site close to the target place. The gauze functioned as a working station and prevented Seprafilm from directly attaching to the surrounding tissue, which allowed the surgeons to handle it with ease. The gauze was used to press Seprafilm onto the target area and could be easily removed through a 12‐mm trocar. Through this method, Seprafilm was successfully applied in all cases and the average time of applying one sheet was 100 seconds. There was no small bowel obstruction within 30 days after surgery.DiscussionThis method neither requires special training nor special equipment only used for Seprafilm. Moreover, it can be easily introduced to every surgeon for the application of Seprafilm during laparoscopic surgery.
Participation of Victorian Thoroughbreds in the racing industry: a whole‐of‐population benchmark
Authors: Flash ML , Crabb HK , Hitchens PL , Firestone SM , Stevenson MA , Gilkerson JR 
Published: October 2021

The proportion of Thoroughbred (TB) horses that commence training and eventually race, is an important industry‐level indicator of how successful it is at producing horses suitable for racing. It is also of interest to the wider community and is central to the issue of whether there is overbreeding in the Australian TB industry. This study investigated the training and racing records for the 2005 and 2010 Victorian TB foal crops to determine the proportion of TBs that train and race, and the age of entering training and first race start. Subsets of the foal crop were also examined to determine if premier yearling sale cohorts would produce selection bias. The Australian Stud Book (ASB) registered 7662 TB horses born in Victoria in 2005 (n = 4116) and 2010 (n = 3546). Of these, 5614 (73%) entered training and 4868 (64%) started in at least one race. Fourteen percent (n = 1045) of the study cohort had their first race start as 2‐year‐olds and 35% (n = 2644) had their first start as 3‐year‐olds. A higher proportion of TB horses that attended premier yearling sales entered training (93%) and raced (84%). This study established a baseline for training and racing milestones, such as the proportion and age that horses commenced training, and age of first start using population‐level data. It also established that the use of subsets of the population can introduce selection bias.
A homozygous loss‐of‐function mutation in FBXO43 causes human non‐obstructive azoospermia
Authors: Wu Huan , Zhang Xin , Shen Qunshan , Liu Yiyuan , Gao Yang , Wang Guanxiong , Lv Mingrong , Hua Rong , Xu Yuping , Zhou Ping , Wei Zhaolian , Tao Fangbiao , He Xiaojin , Cao Yunxia , Liu Mingxi 
Published: October 2021

AbstractNon‐obstructive azoospermia (NOA) represents one of the most serious forms of male infertility caused by spermatogenic failure. Despite multiple genes found to be associated with human NOA, the genetic basis of this idiopathic disease remains largely unknown. FBXO43 is a direct inhibitor of the anaphase‐promoting complex/cyclosome (APC/C) E3 ligase and crucially important in mouse spermatogenesis. In this study, for the first time, we identified a homozygous nonsense mutation in FBXO43 c.1747C > T:p.Gln583X in two NOA brothers from a Chinese consanguineous family via whole‐exome sequencing. FBXO43 was absent from testicular tissue of the proband, and FBXO43‐immunostaining signals were invisible in the affected seminiferous tubules. Furthermore, in humans, FBXO43 defects cause meiotic arrest within early diplotene of prophase I. The results here demonstrate the pathogenicity of this loss‐of‐function mutation and confirmed that spermatocytes were unable to complete meiotic divisions without FBXO43 in humans. In mouse testicular protein extracts, three subunits of the APC/C, including ANAPC2, ANAPC8 and ANAPC10, were validated to interact directly with FBXO43, whereas no interactions were detected for FBXO43 and SKP1. This study furthers our understanding of the genetic basis of human NOA and provides insights into FBXO43 and male infertility.
Vascular epiphytes contribute disproportionately to global centres of plant diversity
Authors: Taylor Amanda , Zotz Gerhard , Weigelt Patrick , Cai Lirong , Karger Dirk Nikolaus , König Christian , Kreft Holger 
Published: October 2021

AbstractAimVascular epiphytes are ubiquitous components of wet tropical forests where they contribute substantially to local and regional plant diversity. While some basic epiphyte distribution patterns are relatively well studied, little effort has been made to understand the drivers responsible for constraining their global distribution. This study quantifies the substantial contribution of epiphytes to global gradients and centres of vascular plant diversity and explores whether epiphytes vary from terrestrial plants in relation to contemporary and historical environmental variables.LocationGlobal.Time periodPresent.Major taxa studiedTracheophyta.MethodsUsing a comprehensive epiphyte species list (EpiList 1.0), and distribution information for 27,850 epiphyte species derived from numerous literature sources, we describe the global biogeography of epiphytes. We use generalized linear mixed effects models to assess the relationship between epiphytic and terrestrial plant diversity, and contemporary and historical environmental predictors.ResultsEpiphytes substantially contribute to global centres of vascular plant diversity, accounting for up to 39% of the vascular flora in Neotropical regions. Epiphytes decrease in species numbers with increasing latitude at a rate three times faster than terrestrial plants, a trend that is driven mainly by the distribution of tropical forests and precipitation. Further, large regional differences emerge that are explained by several large endemic angiosperm families (e.g., Neotropical Bromeliaceae) that are absent in other tropical regions.Main conclusionsOur results show that epiphytes are disproportionately diverse in most global centres of plant diversity and play an important role in driving the global latitudinal diversity gradient for plants. The distribution of precipitation and tropical forest area emerge as major drivers of the latitudinal diversity gradient in epiphyte species richness. Finally, our findings demonstrate how epiphyte floras in different biogeographical realms are composed of different families and higher taxa, revealing an important signature of historical biogeography.
Search Club: Using peer support to develop search skills and share knowledge in a specialist NHS team
Authors: Nicholas Katie , Hopkins Emily , Jordan Liz , McCrossan Jo , Hunt Matt , Greenfield Katy 
Published: October 2021

AbstractThe newly‐formed Knowledge Management team at Health Education England (HEE) established an internal “Search Club” for their Knowledge Specialists to share good practice, exchange ideas, and discuss approaches to developing search strategies. The article describes how this was initiated and run online. The sessions improved the Knowledge Management team skills, and gave them an opportunity to share and learn from each other. A further benefit has been the creation of resources such as a “synonyms bank”, search strategies, and a bank of grey literature sources. These reduce duplication of effort, save time, and improve consistency across the team's output. D.I.
Children living with HIV in Europe: do migrants have worse treatment outcomes?
Authors: Chappell Elizabeth , Kohns Vasconcelos Malte , Goodall Ruth L. , Galli Luisa , Goetghebuer Tessa , Noguera‐Julian Antoni , Rodrigues Laura C. , Scherpbier Henriette , Smit Colette , Bamford Alasdair , Crichton Siobhan , Navarro Marissa Luisa , Ramos Jose T. , Warszawski Josiane , Spolou Vana , Chiappini Elena , Venturini Elisabetta , Prata Filipa , Kahlert Christian , Marczynska Magdalena , Marques Laura , Naver Lars , Thorne Claire , Gibb Diana M. , Giaquinto Carlo , Judd Ali , Collins Intira Jeannie ,   The European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC)
Published: October 2021

AbstractObjectivesTo assess the effect of migrant status on treatment outcomes among children living with HIV in Europe.MethodsChildren aged < 18 years at the start of antiretroviral therapy (ART) in European paediatric HIV observational cohorts where ≥ 5% of children were migrants (defined as born abroad) were included. Three outcomes were considered: (i) severe immunosuppression‐for‐age; (ii) viraemic viral load (≥ 400 copies/mL) at 1 year after ART initiation; and (iii) AIDS/death after ART initiation. The effect of migrant status was assessed using univariable and multivariable logistic and Cox models.ResultsOf 2620 children included across 12 European countries, 56% were migrants. At ART initiation, migrant children were older than domestic‐born children (median 6.1 vs. 0.9 years, p < 0.001), with slightly higher proportions being severely immunocompromised (35% vs. 33%) and with active tuberculosis (2% vs. 1%), but a lower proportion with an AIDS diagnosis (14% vs. 19%) (all p < 0.001). At 1 year after beginning ART, a lower proportion of migrant children were viraemic (18% vs. 24%) but there was no difference in multivariable analysis (p = 0.702), and no difference in severe immunosuppression (p = 0.409). However, there was a trend towards higher risk of AIDS/death in migrant children (adjusted hazard ratio = 1.51, 95% confidence interval: 0.96–2.38, p = 0.072).ConclusionsAfter adjusting for characteristics at ART initiation, migrant children have virological and immunological outcomes at 1 year of ART that are comparable to those who are domestic‐born, possibly indicating equity in access to healthcare in Europe. However, there was some evidence of a difference in AIDS‐free survival, which warrants further monitoring.
Do you lose by doing more? How organizational citizenship behavior directed to the organization relates to career development
Authors: Shang Congyong , Li Dongxu , Weng Qingxiong (Derek) 
Published: October 2021

AbstractBased on social exchange theory, we develop a moderated mediation model, which posits that the indirect relationship between organizational citizenship behavior directed to the organization (OCBO) and organizational reward growth via leader–member exchange (LMX) is moderated by employee political skill. Overall, two studies using cross‐sectional data and three‐wave data supported our model. Specifically, results suggest that (1) OCBO was positively related to LMX; (2) there was a stronger positive relationship between OCBO and LMX when employee political skill was high rather than low; (3) LMX mediates the relationship between OCBO and organizational reward growth; and (4) the indirect effect of OCBO in predicting organizational reward growth via LMX was stronger when employee political skill was high rather than low.
Youth psychopathology: Universal or culture‐specific? Testing the syndrome models of youth self‐report in Chinese population
Authors: Liu Jianghong , Chan Clare , Leung Patrick W. L. 
Published: October 2021

AbstractProblemThe debate on whether psychiatric symptoms are universal and to what extent they are affected by culture is generally divided between the universalist and relativist approaches.MethodsThis study compared Achenbach/Rescorla's model and Weisz's model of youth self‐report in 2521 Chinese adolescents (mean age = 12 years). Indigenous exploratory factor analyses were conducted to explore the factor structure of youth self‐report (YSR), and the derived models were tested with confirmatory factor analysis.FindingsThese analyses indicated good support of the Chinese YSR models for males and females. Further analyses revealed three syndromes, namely anxious/depressed, somatic complaints, and aggressive behaviors, which represented broad internalizing and externalizing factors. These syndromes consistently demonstrated high correlations across the different models, indicating their universal nature. Conversely, some unique factors emerged in the Chinese YSR model, such as weight concern and rule‐breaking behavior, which may reflect underlying culture‐bound factors.ConclusionsOur findings support a combined perspective to the universalist and relativist approaches, which argues that some syndromes including Anxious/Depressed, Somatic Complaints, Aggressive Behavior and Attention Problems are more likely to be universal in male adolescents, while a new emerging syndrome like Weight Concern may reflect the socioeconomic, culture, and lifestyle changes that are currently emerging in China.