bluuebunny/crossref_metadata_2025_split huggingface dataset:
Table-to-Text Generation with Accurate Content Copying
Authors: Yang Yang , Cao Juan , Wen Yujun , Zhang Pengzhou 
Published: August 2021

Abstract
Table-to-text generation is an important task in natural language generation that aims to generate smooth, informative text based on structured data. In this paper, we propose a novel transformer-based autoregressive model that incorporates table content copying and language model based generation. At first, we propose a word transformation method to process a target text. By using target text containing fields and position information, we can help the model learn the relationship between target text and table and gain the position of where to copy. We then propose two auxiliary learning goals: table-text constraint loss and copy loss. Table-text constraint loss is introduced to effectively model table inputs, whereas copy loss is exploited to precisely copy word fragments from a table. In addition, we change the maximization-based text search strategy to reduce the probability of problems such as sentence repetition and inconsistency. On the WIKIBIO dataset, our model improves its BLUE scores from 45.47 to 46.87 and ROUGE scores from 41.54 to 42.28, outperforming state-of-the-art baseline models on automatic evaluation metrics. On the ROTOWIRE test set, compared with the best baseline model, our model gets 4.29% higher on CO metric, and 1.93 points higher on BLEU.
In Situ Atomic-Scale Observation of Dislocation Climb and Grain Boundary Transformation in Nanostructured Metal
Authors: Chu Shufen , Liu Pan , Zhang Yin , Wang Xiaodong , Song Shuangxi , Zhu Ting , Zhang Ze , Han Xiaodong , Sun Baode , Chen Mingwei 
Published: August 2021

Abstract
We report atomic-scale observations of grain boundary (GB) dislocation climb in nanostructured Au during in situ straining at room temperature. Climb of a dislocation occurs by stress-induced reconstruction of two atomic columns at the edge of an extra half atomic plane in the dislocation core. Different from the conventional belief of dislocation climb by destruction or construction of a single atomic column at the dislocation core, the new atomic route is demonstrated to be energetically favorable by Monte Carlo simulations. Our in situ observations also reveal GB transformation through dislocation climb, which suggests a means of controlling microstructures and properties of nanostructured metals.
Complementary Approaches for Military Women with Chronic Pelvic Pain: A Randomized Trial
Authors: Crisp Carol D , Baldi Robert , Fuller Matthew , Abreu Eduardo , Nackley Andrea G 
Published: August 2021

Abstract
Introduction: Active-duty (AD) women suffer with chronic pelvic pain (CPP) while providers tackle diagnoses and treatments to keep them functional without contributing to the opioid epidemic. The purpose of this study was to determine the effectiveness of non-invasive, self-explanatory mindfulness-based stress reduction (MBSR) or self-paced healthy lifestyle (HL) interventions on CPP in AD women.Methods: We conducted a six-week interventional prospective study with AD women aged 21–55 at Mountain Home (MTHM), Idaho. Women were randomly assigned to MBSR (N = 21) or HL (N = 20) interventions. The primary outcome was pain perception. Secondary outcomes were depression and circulating cytokine levels.Results: Women in the MBSR group exhibited reduced pain interference (P < .01) and depression (P < .05) alongside decreased IL-4 (P < .05), IL-6 (P < .05), eotaxin (P < .05), MCP-1 (P = .06), and IL-1ra (P < .01) and increased VEGF (P < .05). Those in the HL group did not have changes in pain, however, did exhibit reduced depression (P < .05) alongside decreased GM-CSF (P < .05) and increased TNFα (P < .05), SDF-1 (P < .01), and IL-1ra (P < .01).Conclusion: AD women receiving MBSR or HL had reduced depression scores and altered circulating cytokine levels, however only those receiving MBSR had reduced pain perception. Findings support MBSR as an effective and viable behavioral treatment for AD women suffering from CPP.
The Effect of Heat Treatment on Fracture Behavior in ENiCrFe-7 Weld Overlay Cladding Materials
Authors: Guo Peiliang , Han H.G. 
Published: August 2021

Abstract
The effect of heat treatment (as-weld, 615℃/48h) on fracture behavior in ENiCrFe-7 weld overlay cladding material was investigated. There were more NbC precipitates in the interdendrites for the heat treatment one after 615℃/48h than that of as-weld, which resulted in the lattice distortion in the interdendrites reduced by the heat treatment. As a result, the fractography was classified as brittle and transgranular fracture and the interdendrites played a major role in the failure of as-weld Alloy ENiCrFe-7, and the fractography was ductility fracture for the heat treatment one after 615℃/48h.`
In Silico Molecular Docking Approach Against Enzymes Causing Alzheimer’s Disease Using Borassus Flabellifer Linn
Authors: Abraham Jason Tom , Maharifa H. Noorul Samsoon , Hemalatha S 
Published: August 2021

Abstract
Alzheimer’s disease is a life-threatening neurodegenerative disorder. About 50 million people across the globe are affected by this disease. At final stages, this disease causes patients to lose cognitive ability, memory and brain cells to the point of being totally depend on other individuals for livelihood. The incidence of this disease is increasing across the world in the recent years, making the need of a better drug an urgency. Existing drugs show various side-effects and natural sources of medicinal drugs are being explored. In this study, we explore the activity of natural compounds isolated through GCMS analysis from the haustoria of palmyra palm against two major Alzheimer’s disease-causing enzymes, β-amyloid and Acetylcholinesterase. The binding affinity of these compounds against the target proteins and their pharmacokinetic properties were checked. Among the 37 compounds docked, 5 compounds showed good binding affinity and pharmacokinetic properties. These natural compounds showed a potential as a drug against Alzheimer’s disease. Further research is needed to study the synergistic activity of the compounds in live cells.
Omitting Surgery In Esophageal Cancer Patients With Complete Response After Neoadjuvant Chemoradiotherapy: A Systematic Review And Meta-Analysis
Authors: Park Jaehyeon , Yea Ji woon , Park Jaewon 
Published: August 2021

Abstract
Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is a standard treatment modality for locally advanced esophageal cancer. However, patients who achieve clinical complete response (cCR) after nCRT have been reported to have better prognosis. Further, the role of surgery in these patients is controversial. Thus, this meta-analysis aimed to evaluate whether surgery is still useful in patients with cCR after nCRT. We systematically reviewed the MEDLINE, PubMed, Embase, Cochrane library, and Scopus databases for studies on surgical efficacy in complete responders after concurrent chemoradiotherapy for esophageal cancer. The publication date was set to January 1, 2010–January 31, 2020. The hazard ratio (HR) and risk ratio was used to compare 2-year overall survival (OS), disease-free survival (DFS), incidence of locoregional failure, distant metastasis and treatment mortality between the nCRT and the nCRT plus surgery groups. Six articles involving 609 patients were included. There was a significant benefit of nCRT for OS (HR = 0.80, 95% confidence interval [CI] = 0.64–0.99, p = 0.04), but not for DFS (HR = 1.19, 95% CI = 0.41–3.46, p = 0.75). The nCRT group tended to have lower mortality than the nCRT plus surgery group (risk ratio = 0.15, 95% CI = 0.02–1.18, p = 0.07). Omitting surgery provides better OS in complete responders after nCRT. Adding surgery could increase the morbidity and mortality and decrease the quality of life. Thus, nCRT alone could be a feasible approach for patients with cCR.
Study on the Mechanism of Lupenone for Treating type 2 Diabetes by Integrating Pharmacological Evaluation and Network Pharmacology
Authors: Xu Feng , Wu Hongmei , Wang Yuanmin , Yang Ye , Wang Xiangpei 
Published: August 2021

Abstract
Background: Lupenone (LUP) is the active ingredient of Rhizoma Musae, which has good anti-diabetes effects, but the underlying mechanism is unclear. In this study, animal experiments combined with network pharmacology were used to explore the mechanism of LUP for treating diabetes. Methods: Type 2 diabetic rats with insulin resistance (IR) were induced by a high-fat diet and streptozotocin. the fasting blood glucose (FBG), index of oxidative stress, blood lipids, and IR-related targets in skeletal muscle and adipose were detected. a network pharmacology-based strategy was also adopted to clarify the mechanism of LUP for treating diabetes by improving IR. Results: LUP decreased the FBG levels and synthesis of glycogen, improved oxidative stress and lipid metabolism disorders, and increased the gene and protein expression of insulin receptor, insulin receptor substrate (IRS)-1, IRS-2, glucose transporter type 4 (GLUT-4) in skeletal muscle and peroxisome proliferator-activated receptor γ, IRS-1, IRS-2, GLUT-4 in adipose. Network pharmacology analysis revealed that LUP improves IR by multiple targets (like INS, TP53, TNF, SRC and ESR1) and signal pathways. Conclusion: These results suggested that the mechanism of LUP for treating diabetes is closely related to improving IR. LUP has the potential to develop as a new drug for the treatment of type 2 diabetes.
Tailoring plasmon excitations in α − T3 armchair nanoribbons
Authors: Iurov Andrii , Zhemchuzhna Liubov , Gumbs Godfrey , Huang Danhong , Fekete Paula , Anwar Farhana , Dahal Dipendra , Weekes Nicholas 
Published: August 2021

Abstract
We have calculated and investigated the electronic states, dynamical polarization function and the plasmon excitations for α − T3 nanoribbons with armchair-edge termination. The obtained plasmon dispersions are found to depend significantly on the number of atomic rows across the ribbon and the energy gap which is also determined by the nanoribbon geometry. The bandgap appears to have the strongest effect on both the plasmon dispersions and their Landau damping. We have determined the conditions when relative hopping parameter α of an α − T3 lattice has a strong effect on the plasmons which makes our material distinguished from graphene nanoribbons. Our results for the electronic and collective properties of α − T3 nanoribbons are expected to find numerous applications in the development of the next-generation electronic, nano-optical and plasmonic devices.
Gene cloning, functional expression and characterization of a novel GH46 chitosanase from Streptomyces avermitilis (SaCsn46A)
Authors: Guo Jing , Wang Yi , Gao Wenjun , Wang Xinrou , Gao Xin , Man Zaiwei , Cai Zhiqiang , Qing Qing 
Published: August 2021

Abstract
A novel glycoside hydrolase (GH) family 46 chitosanase (SaCsn46A) from Streptomyces avermitilis was cloned and functionally expressed in Escherichia coli Rosetta (DE3) strains. SaCsn46A consists of 271 amino acids, which includes a 34-amino acids signal peptide. The protein sequence of SaCsn46A shows maximum identity (83.5%) to chitosanase from Streptomyces sp. SirexAA-E. Then the mature enzyme was purified to homogeneity through Ni-chelating affinity chromatography with a recovery yield of 78% and the molecular mass of purified enzyme was estimated to be 29 kDa by SDS-PAGE. The recombinant enzyme possessed a temperature optimum of 45 oC and a pH optimum of 6.2, and it was stable at pH ranging from 4.0 to 9.0 and below 30 oC. The Km and Vmax values of this enzyme were 1.32 mg∙mL− 1, 526.32 µM∙mg− 1∙min− 1, respectively (chitosan as substrate). The enzyme activity can be enhanced by Mg2+ and especially Mn2+, which could enhance the activity about 3.62-fold at a 3 mM concentration. The enzyme can hydrolyze a variety of polysaccharides which linked by β-1,4-glycosidic bonds such as chitin, xylan and cellulose, but it could not hydrolyze polysaccharides linked by α-1,4-glycosidic bonds. The results of thin layer chromatography and HPLC showed that the enzyme exhibited an endo-type cleavage pattern and could hydrolyze chitosan to glucosamine (GlcN) and (GlcN)2. This study demonstrated that SaCsn46A is a promising enzyme to produce glucosamine and chitooligosaccharides (COS) from chitosan.
Design of Hybrid Narrow-Band Plasmonic Absorber Based on Chalcogenide Phase Change Material in the Infrared Spectrum
Authors: Oliveira Israel Alves , Souza I. L. Gomes , Rodriguez-Esqu V. F. 
Published: August 2021

Abstract
Structures absorbing electromagnetic waves in the infrared spectral region are important optical components in key areas such as biosensors, infrared images and thermal emitters, and require special attention from reconfigurable devices. We propose a three-dimensional metal-dielectric plasmonic absorber with a layer of PCM's (Phase Change Materials). The phase shift effects of PCMs are analyzed, and it is possible to obtain a displacement control in the resonant absorption peaks between the amorphous and crystalline states using the Lorentz-Lorenz relation. Aided in this empirical relation, we analyzed the absorption shift in the intermediate phases between them. The geometric parameters of the structure with the pcm material layer in the semi-crystalline state were optimized to present strong absorption for normal incidence. The effects of the oblique incidence for the TM and TE polarization modes were also analyzed. Our results demonstrate that PCMs have great potential for reconfigurable nanophotonic devices.
LMWF5A Demonstrates an Anti-Inflammatory Mode of Action and Similar Drug Targets to Dexamethasone in Activated PBMC
Authors: Frederick Elizabeth D. , Hausburg Melissa A. , Thomas Gregory W. , Bar-Or David 
Published: August 2021

Abstract
The low molecular weight fraction of human serum albumin (LMWF5A) has proven immunomodulatory activity via its effects on multiple inflammatory mediators and transcription factors. This biologic drug is currently being evaluated for the treatment of conditions characterized by hyperactive or persistent immune responses. To gain further insight into the mechanism of action of LMWF5A, an unbiased investigation of its effects on activated immune cells was performed. Peripheral blood mononuclear cells (PBMC) were treated with vehicle control or LMWF5A and stimulated with lipopolysaccharide (LPS), LPS/interferon γ, or interleukin (IL)-4/IL-13 for 24h. Differential gene expression analysis by RNAseq was performed to determine transcriptional changes due to LMWF5A treatment in each stimulation condition. Ingenuity Pathway Analysis software was employed to reveal overall biological trends observed in the RNAseq datasets and to identify compounds with comparable or contrasting activities to LMWF5A. Analysis of each RNA dataset revealed broad anti-inflammatory and pro-resolving activities for LMWF5A, with predicted inhibition of key pro-inflammatory mediators and functions as well as activation of some anti-inflammatory mediators. Upstream regulator analysis confirmed these activities and identified the corticosteroid dexamethasone as the most significantly similar regulator. Further comparison of LMWF5A and dexamethasone revealed similar, but not identical, targets and directional regulation. This study supports our current knowledge on the mode of action of LMWF5A and provides new hypotheses for future investigations. Due to its analogous biological effects with dexamethasone and known safety profile, LMWF5A may be used to treat conditions that are supported for dexamethasone with fewer or less harmful side effects.
Carbon Black Nanoparticles Exposure Induces Intestinal Flora Dysbiosis and Consequent Activation of Gut-liver Axis Leading to Liver Lipid Accumulation in Zebrafish
Authors: Liu Qingqing , Wang Bing , Wang Shengchen , Jing Hongyuan , Xu Shiwen 
Published: August 2021

Abstract
BackgroundCarbon black nanoparticles (CBNPs) are a major carbonaceous nanomaterial, which have been widely left in the environment. The integrity of the gut-liver axis function is critical to the survival of animals. Therefore, we studied the effects of three concentrations of CBNPs (50, 100, 200 mg/L) on zebrafish intestines, liver and intestinal flora. ResultsThe results showed that CBNPs exposure could reduce the diversity of intestinal flora, change the structure of core microbial populations, enhance the permeability of the intestinal mucosal barrier, and cause changes in genes related to tight junctions in intestinal tissues. The H&E staining and Oil red O staining showed that CBNPs exposure would lead to vacuolar degeneration and lipid accumulation in zebrafish liver. Further detection of glycolipid metabolism related genes showed that CBNPs exposure induced the up-regulation of glycolysis related genes PFKFB3, LDHA, and LEPr, reduces the expression of glycogen synthase kinase GSK-3b, and increases lipid transport and production related genes PPAR-α, PPAR-γ, LIPC, apoa4, Fabp2 and Fabp11 expression. ConclusionsIn brief, our data demonstrated that CBNPs exposure induced intestinal microflora disturbance in zebrafish can lead to liver lipid accumulation.
Experimental Validation and Numerical Simulation of Flexible and Micro-scale Roll Gap Control Technology
Authors: Yang Tingsong , Chen Qifa , Feng Yanfeng , Hai Yang , Du Fengshan 
Published: August 2021

Abstract
To obtain a better ability of strip flatness control, this paper proposes a new flexible and micro-scale roll gap control technology. According to the principle of roll profile electromagnetic control technology (RPECT), a new electromagnetic control rolling mill with the function of roll profile control and large diameter ratio rolling is designed and built. To analyze the flatness control ability of this mill, a comprehensive finite element model (FEM) is established and verified, which includes a FEM for predicting the electromagnetic control roll profile and a FEM of rolling process. The simulation results show that the crown control ability of RPECT is stronger than the quadratic crown control ability, and the effect of tension on the roll gap shape crown is small. The results in the indentation experiment and the rolling experiment show that increasing the roll crown of electromagnetic control roll can adjust the strip shape form edge wave to non-wave, and middle wave. The feasibility of using RPECT to adjust the roll gap shape has been verified, and the roll gap control goal of uniform transverse size distribution can be achieved.
The Unexpected Relationship Between Extreme Shear Events and AMO
Authors: qiu weiteng , yan xiaodong 
Published: August 2021

Abstract
The vertical shear–the change in wind speed with height-of horizontal winds is a serious threat to the safety of aircraft. Yet their global distribution is not fully understood. We creatively used a precise method to calculate different types of vertical shear at four isobaric surfaces during the period of 1979~2018. The occurrence of severe shear events has increased by 19%, and they mostly occur over the equatorial ocean and within the mid-high latitude zone of the Northern hemisphere, while light shear event occurrence has been reduced by 21%. Variations of severe shear are modulated by the Atlantic Multidecadal Oscillation (AMO), which affects the frequency of shear events by influencing the intertropical convergence zone (ITCZ). Our study implies that severe shear events are regulated by internal climate variability.
Should the susceptibility of cervid to coronaviruses be a matter of concern?
Authors: Lopes Luciano Rodrigo 
Published: August 2021

Abstract
The susceptibility of the white-tailed deer (Odocoileus virginianus) to SARS-CoV-2 has highlighted cervids as a new coronavirus reservoir. Cervids are known hosts for other coronaviruses (such as bovine-like coronavirus) and can harbour several pathogens that cause serious diseases in humans. Moreover, herds of cervids are largely distributed among wildlife and are in close contact with humans, who often hunt or rear these animals The increased incidence of severe acute coronavirus 2 (SARS-CoV-2) infections, especially in American countries, which serve as habitats for many cervids, including the white-tailed deer and other closely related species, can favour the transmission of coronaviruses from humans to wild animals. In this context, this letter briefly discusses some points that underscore the occurrence of SARS-CoV-2 infections in cervids as a matter of concern.
Machine learning and deep learning techniques to support the clinical diagnosis of arboviral diseases: A systematic review
Authors: Neto Sebastião Rogério da Silva , Oliveira Thomás Tabosa , Teixeira Igor Vitor , de Oliveira Samuel Benjamin Aguiar , Sampaio Vanderson Souza , Lynn Theo , Endo Patricia Takako 
Published: August 2021

Abstract
Background: NTDs primarily affect the poorest populations, often living in remote, rural areas, urban slums or conflict zones. Arboviruses are a significant NTD category spread by mosquitoes. Dengue, Chikungunya, and Zika are three arboviruses that affect a large proportion of the population in Latin and South America. The clinical diagnosis of these arboviral diseases is a difficult task due to the concurrent circulation of several arboviruses which present similar symptoms, inaccurate serologic tests resulting from cross-reaction and co-infection with other arboviruses. Objective: The goal of this paper is to present evidence on the state of the art of studies investigating the automatic classification of arboviral diseases to support clinical diagnosis based on ML and DL models. Method: We carried out a SLR in which Google Scholar was searched to identify key papers on the topic. From an initial 963 records (956 from string-based search and 7 from single backward snowballing technique), only 15 relevant papers were identified. Results: Results show that current research is focused on the binary classification of Dengue, primarily using Tree based ML algorithms and only one paper was identified using DL. Five papers presented solutions for multi-class problems, covering Dengue (and its levels) and Chikungunya. No papers were identified that investigated models to differentiate between Dengue, Chikungunya, and Zika. Conclusions: The use of an efficient clinical decision support system for arboviral diseases can improve the quality of the entire clinical process, thus increasing the accuracy of the diagnosis and the associated treatment. It should help physicians in their decision-making process and, consequently, improve the use of resources and the patient's quality of life.
Nucleic Acid Sequence Composition of the Oxford – AstraZeneca Vaccine ChAdOx1 nCoV-19 (AZD1222, Vaxzevria)
Authors: Radukic Marco T. , Le Dinh To , Müller Kristian M. 
Published: August 2021

Abstract
The vaccine ChAdOx1 nCoV-19 has been widely used, but its purity has been disputed because of rare side effects. We used Nanopore sequencing to assess the sequence and genetic purity of a vaccine dose. As we were lacking a reference sequence for the antigen cassette, we provide the obtained annotated sequence of the full vector to aid further studies on this topic. Our sample adhered to the published data, was highly pure (>99.97%), and no copy of the E1 gene as a predictor on replication-competent escape mutants was found.