bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cognitive performance in pain is predicted by effort, not goal desire
Authors: Pickering Jayne , Attridge Nina , Inglis Matthew 
Published: November 2021

Background
Pain’s disruptive effects on cognition are well documented. The seminal goal-pursuit account of pain suggests that cognitive disruption is less likely if participants are motivated to attended to a focal goal and not a pain goal.

Objectives
Existing theory is unclear about the conceptualisation and operationalisation of ‘focal goal’. This study aims to clarify how goals should be conceptualised and further seeks to test the theory of the goal-pursuit account.

Methods
In a pre-registered laboratory experiment, 56 participants completed an arithmetic task in high-reward/low-reward and pain/control conditions. Pain was induced via cold-water immersion.

Results
High levels of reported effort exertion predicted cognitive-task performance, whereas desire for rewards did not. Post-hoc analyses further suggest that additional effort in the pain condition compensated for pain’s disruptive effects, but when this extra effort was not exerted, performance deficits were observed in pain, compared to control, conditions.

Conclusion
Results suggest that ‘motivation’, or commitment to a focal goal, is best understood as effort exertion and not as a positive desire to achieve a goal. These results solidify existing theory and aid researchers in operationalising these constructs.
Computer tomography guided thoracoscopic resection of small pulmonary nodules in the hybrid theatre
Authors: Karampinis Ioannis , Rathmann Nils , Kostrzewa Michael , Diehl Steffen J. , Schoenberg Stefan O. , Hohenberger Peter , Roessner Eric D. 
Published: November 2021

Purpose
Thoracic surgeons are currently asked to resect smaller and deeper lesions which are difficult to detect thoracoscopically. The growing number of those lesions arises both from lung cancer screening programs and from follow-up of extrathoracic malignancies. This study analyzed the routine use of a CT-aided thoracoscopic approach to small pulmonary nodules in the hybrid theatre and the resulting changes in the treatment pathway.

Methods
50 patients were retrospectively included. The clinical indication for histological diagnosis was suspected metastasis in 46 patients. Technically, the radiological distance between the periphery of the lesion and the visceral pleura had to exceed the maximum diameter of the lesion for the patient to be included. A spiral wire was placed using intraoperative CT-based laser navigation to guide the thoracoscopic resection.

Results
The mean diameter of the lesions was 8.4 mm (SD 4.27 mm). 29.4 minutes (SD 28.5) were required on average for the wire placement and 42.3 minutes (SD 20.1) for the resection of the lesion. Histopathology confirmed the expected diagnosis in 30 of 52 lesions. In the remaining 22 lesions, 9 cases of primary lung cancer were detected while 12 patients showed a benign disease.

Conclusion
Computer tomography assisted thoracoscopic surgery (CATS) enabled successful resection in all cases with minimal morbidity. The histological diagnosis led to a treatment change in 42% of the patients. The hybrid-CATS technique provides good access to deeply located small pulmonary nodules and could be particularly valuable in the emerging setting of lung cancer screening.
Barriers and facilitators to physical activity in second-generation British Indian women: A qualitative study
Authors: Bhatnagar Prachi , Foster Charlie , Shaw Alison 
Published: November 2021

Aim
To understand the barriers to and motivations for physical activity among second-generation British Indian women.

Subject
Approximately 50% of British South Asians are UK-born, and this group is increasing as the second-generation also have children. Previous research into the barriers to and facilitators for physical activity has focused on migrant, first-generation populations. Qualitative research is needed to understand a) how we might further reduce the gap in physical activity levels between White British women and British Indian women and b) the different approaches that may be required for different generations.

Methods
Applying a socioecological model to take into account the wider social and physical contexts, we conducted semi-structured interviews with 28 Indian women living in Manchester, England. Interviews with first-generation British Indian women were also included to provide a comparator. Interviews were audio-recorded, transcribed, thematically coded and analysed using a grounded theory approach.

Results
Ways of socialising, concerns over appearance while being physically active, safety concerns and prioritising educational attainment in adolescence were all described as barriers to physical activity in second-generation British Indian women. Facilitators for physical activity included acknowledging the importance of taking time out for oneself; religious beliefs and religious groups promoting activity; being prompted by family illness; positive messages in both the media and while at school, and having local facilities to use.

Conclusions
Barriers to physical activity in second-generation Indian women were very similar to those already reported for White British women. Public health measures aimed at women in the general population may also positively affect second-generation Indian women. First-generation Indian women, second-generation children and Muslim women may respond better to culturally tailored interventions.
Assessment of knowledge of drug-food interactions among healthcare professionals in public sector hospitals in eThekwini, KwaZulu-Natal
Authors: Osuala Emmanuella Chinonso , Tlou Boikhutso , Ojewole Elizabeth Bolanle 
Published: November 2021

BackgroundFoods and the nutrients they contain can interact with drugs and thereby interfere with their therapeutic safety and efficacy. Adequate knowledge of healthcare professionals (HCPs) about drug-food interactions can help in preventing potential drug-food interactions among patients. This study aimed to assess the knowledge of HCPs about common drug-food interactions.MethodsA cross-sectional study was carried out among 459 HCPs from three public hospitals in eThekwini district, KwaZulu-Natal between November 2018, and January 2019. Informed consent was obtained from the HCPs, and a structured questionnaire was thereafter administered. Data were analysed using SPSS® version 25. Factors associated with knowledge of the HCPs were determined using logistic regression analysis.ResultsOf the 459 participants, 22.2% (n = 102) were doctors, 11.3% (n = 52) pharmacists, 63.8% (n = 293) nurses and 2.6% (n = 12) dietitians. Most of the HCPs were females 79.7% (n = 366), the mean age of the HCPs was 38.61±0.48. The knowledge score of the HCPs was 22.66±0.25 out of an overall score of 46. The HCPs poorly identified food types that interact with drugs and correct administration time of drugs relative to meals. Being a pharmacist (OR: 14.212, CI: 4.941–40.879, p<0.001), doctor (OR: 5.223, CI: 2.146–12.711, p<0.001), or a dietitian (OR: 5.476, CI: 1.103–27.191, p = 0.038) was associated with higher knowledge of drug-food interactions.ConclusionThe HCPs in this survey had low drug-food interaction knowledge. These findings suggest the need for additional training and educational courses for the HCPs on drug-food interactions.
The Professional Identity: Concept and Significance for Improving the Efficiency of Education of Law Students
Authors: Kalashnik Natalya , Neimark Maria , Kiseleva Elena 
Published: November 2021

The article deals with the problem of forming the professional identity of law students. Domestic and foreign approaches to the definition of the concept of "professional identity" are analyzed, the authors’ definition of professional identity is proposed. It is justified that an important condition for the formation of the professional identity of law students is their inclusion in real professional activities, interaction with representatives of various legal professions and persons interested in obtaining legal assistance. This organization of the educational process allows you to study the peculiarities of activity in the performance of duties in various legal specialties, which contributes to the formation of professional identity. The main stages of the development of professional identity fall on the period of study at the university, while practical training of students plays an important role, as a form of organizing educational process when mastering of the educational program happens in the invironment where students perform certain types of work related to future professional work and aimed at the formation, consolidation, development of practical skills and competencies in the profile of the corresponding educational program. Based on the analysis of normative legal acts, an option is proposed to implement practice-based training of students, which allows you to study the content of various legal specialties. It is noted that such development of the educational process will allow students to choose preferred options for legal work, which will ultimately contribute to successful professional growth. It was established that strengthening the practical-oriented part of the educational process in universities will eliminate the existing systemic gap between the level of qualifications of students during study and the degree of effectiveness of their subsequent professional identity as an important condition for the correct choice of the professional sphere.
Long-Term Statin Use, Total Cholesterol Level, and Risk of Colorectal Cancer: A Prospective Cohort Study
Authors: Zhang Yin , Wu Kana , Chan Andrew T. , Meyerhardt Jeffrey A. , Giovannucci Edward L. 
Published: November 2021

INTRODUCTION:
Statin use has been examined as a potential chemopreventive strategy against colorectal cancer (CRC). Previous studies have not been able to investigate this topic with adequate follow-up time or disentangle the effects of statin use and total cholesterol level. We investigated prospectively this topic.

METHODS:
Eligible participants (100,300 women and 47,991 men) in the Nurses' Health Study and Health Professionals Follow-Up Study were followed for up to 24 years. Cox proportional hazards models were used to estimate hazard ratios and 95% confidence intervals.

RESULTS:
We documented 2,924 incident CRC cases during follow-up. In fully adjusted analyses, longer duration of statin use was associated with higher risk of colon cancer (hazard ratios, the 95% confidence interval was 1.09, 0.95–1.25 for 1–5 years; 1.16, 0.99–1.36 for 6–10 years; 1.08, 0.81–1.44 for 11–15 years; 1.85, 1.30–2.61 for >15 years; vs never users, P = 0.004 for trend) rather than rectal cancer. The risk elevation was driven by proximal colon cancer (1.16, 0.98–1.38 for 1–5 years; 1.19, 0.98–1.45 for 6–10 years; 1.25, 0.89–1.74 for 11–15 years; 2.17, 1.46–3.24 for >15 years; vs never users, P = 0.001 for trend) rather than distal colon cancer. The results remained robust in analyses among participants with hypercholesterolemia or who never received screening. Total cholesterol level was not associated with CRC risk.

DISCUSSION:
This study does not support benefit of statin use in CRC chemoprevention or any association between total cholesterol level and CRC risk. On the contrary, long-term statin use may be associated with increased colon cancer risk (driven by proximal colon cancer).
Visibilités digitales du religieux. Introduction
Authors: Catellani Andréa , Servais Olivier , Douyère David 
Published: November 2021

le présent dossier vise à investiguer les formes d’expression et de mise en visibilité digitales du religieux et les raisons de son expansion numérique. Ces formes de mise en visibilité peuvent être opérées par des dévots (Favret-Saada, 2017), des activistes, des acteurs religieux placés en position latérale ou marginale dans leur communauté (Campbell, 2021), ou mises en place par des institutions et des mouvements religieux de types différents. Il s’agit d’examiner à la fois les discours, les images (car le digital porte et enclot d’autres médias, que sont la langue, l’écriture, la parole et l’image, le son et la musique), les dispositifs numériques eux-mêmes et les ergonomies développant le service religieux proposé, mais d’examiner aussi les contextes économiques et socio-politiques qui peuvent motiver, expliquer ou fonder ces communications, dans le cadre d’une vision non pas sociologique mais centrée sur l’information et la communication, soit la production de sens dans une situation d’altérité, recourant à diverses médiations techno-sémiotiques. Il s’agit également de considérer les pratiques (Duteil-Ogata, Jonveaux, 2020) de production et de mobilisation de ces dispositifs, ainsi que leurs théorisations. Car le numérique religieux n’est pas seulement un ensemble de données rendues accessibles en réseau, c’est aussi le fruit d’une incitation, d’une pensée du public et du langage (Douyère, 2020, p. 49-50), une forme de continuation de la pratique, portés par une communauté, en conflit ou non sur ces questions.
Understanding Imagination in Entrepreneurship
Authors: Lecuna Antonio 
Published: November 2021

Abstract
Using interviews to explore the role imagination plays in the South American Nikkei phenomenon (a fusion of Japanese haute cuisine with Peruvian ingredients) and employing the alternate templates research strategy to analytically compare three entrepreneurial behaviors (adaptive bricolage, strategic planning, and transformative effectuation), this case study found that the current theoretical boundary conditions are insufficient to separate the three archetypes. Therefore, based on data, new concepts are proposed to explain entrepreneurial behaviors where they overlap (e.g., creative imagination as a bridging construct of the entrepreneurial process). A novel entrepreneurial trilemma and a behavioral model focused on the conceptual overlaps are introduced to frame the new concepts and to visually depict the relationships between them.
Increasing student involvement in research: a collaborative approach between faculty and students
Authors: Knight Stacey L. , Hale Regina L. , Chisholm LeAnn. J. , Moss Patti , Rolf Carmen , Wenner Lori 
Published: November 2021

Abstract
Baccalaureate nursing curriculum generally include a research or evidence-based practice course, but students may have little opportunity for specific application of the research process during their nursing education. Using Modeling and Role-modeling as a theoretical framework, a scholarly collaboration between faculty and student was developed to promote a unique and engaging undergraduate research endeavor. Faculty researchers developed an exploratory community-based research study to survey the local population about the immediate and lingering physical, financial, psychological, and emotional effects of Hurricane Harvey on the community. The project allowed students to gain invaluable knowledge about the research process, time management techniques, application of theory to the practice setting, community health assessment, collaboration among team members, and achieve student learning outcomes. Student participation in this research project provided necessary collaboration and leadership experiences that will benefit students during school and in their professional practice.
Similarity of mirative and contrastive focus: three parameters for describing attention markers
Authors: Yliniemi Juha 
Published: November 2021

Abstract
This article addresses the heretofore unacknowledged similarity of mirative-like and contrastive-focus-like functions by describing data from Denjongke (Tibetic, sip), Bih (Chamic, Vietnam, ibh) and Nepali (Indo-Aryan, nep). The similarity between mirative-like and contrastive-focus-like functions in the aforementioned languages is captured by the notion of something being brought to the forefront of attention. Mirative-like semantics are shown to be epiphenomenal to attention-oriented phenomena, and the functional domain in which the morphemes operate is shown to be attention rather than knowledge structure. The morphemes in the study are described in terms of three parameters, which are put forward as potentially useful tools for describing similar morphemes in other languages: speaker versus addressee orientation, clausal versus phrasal scope, and anaphoric versus cataphoric use. The first two parameters form a fourfold table in which the heuristically named “mirative-like function” has clausal scope and is speaker-oriented (i.e. speaker signals that something has come to the forefront of their attention). “Contrastive-focus-like function”, on the other hand, has phrasal scope and is addressee-oriented (i.e. speaker intends to bring something to the forefront of the addressee’s attention). Cognitively, contrastive-focus-like function is shown to establish joint attention.
miR-150-5p affects AS plaque with ASMC proliferation and migration by STAT1
Authors: Bian Yuan , Cai Wenqiang , Lu Hongying , Tang Shuhong , Yang Keqin , Tan Yan 
Published: November 2021

Abstract
We explore miR‐150‐5p in atherosclerosis (AS). The AS model was constructed using Apo E−/− mice with an injection of the miR-150-5p mimic or an inhibitor. Pathological characteristics were assessed using Oil red O staining and Masson staining. Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and Western blot were used to analyze the expressions of microRNA-150-5p (miR-150-5p), STAT1, α-SMA (α-smooth muscle actin) and proliferating cell nuclear antigen (PCNA). Targetscan and dual-luciferase reporter assay were used to analyze the interaction between miR-150-5p and STAT1. The viability, migration, cell cycle and α-SMA and PCNA expressions in oxidized low-density lipoprotein (ox-LDL)-stimulated primary human aortic smooth muscle cells (ASMCs) were assessed using molecular experiments. miR-150-5p was reduced in both AS mice and ox-LDL-stimulated human aortic smooth muscle cells but STAT1 had the opposite effect. The miR‐150‐5p inhibitor alleviated the increase of lipid plaque and reduced collagen accumulation in the aortas during AS. Upregulation of α-SMA and PCNA was reversed by miR-150-5p upregulation. STAT1 was targeted by miR‐150‐5p, and overexpressed miR-150-5p weakened the ox-LDL-induced increase of viability and migration abilities and blocked cell cycle in ASMCs, but overexpressed STAT1 blocked the effect of the miR‐150‐5p mimic. This paper demonstrates that miR-150-5p has potential as a therapeutic target in AS, with plaque stabilization by regulating ASMC proliferation and migration via STAT1.
Rapid response of locally advanced oral squamous cell carcinoma to apatinib: A case report
Authors: He Jian , Zhang Yangyang , Gao Jin , Qian Liting 
Published: November 2021

AbstractThere are no effective therapeutic options for locally advanced head and neck squamous cell carcinoma (HNSCC). Additionally, there is no standard therapy for patients subjected to multiple lines of treatment. Angiogenesis plays a key role in tumor growth and metastasis. Therefore, inhibition of tumor angiogenesis is an important strategy for tumor therapy. Apatinib is a novel tyrosine kinase inhibitor that inhibits angiogenesis by targeting vascular endothelial growth factor receptor-2 (VEGFR-2). The effect of apatinib on HNSCC has not been clearly established. In this study, we administered apatinib in combination with anti-epidermal growth factor receptor (EGFR) targeted and systemic chemotherapy for the treatment of oral cancer and to achieve better disease outcomes. To avoid fatal bleeding, after achieving good clinical outcomes, the follow-up treatment plan was adjusted. The efficacy of apatinib combined with anti-EGFR targeted and systemic chemotherapy for the treatment of oral cancer has not been previously reported. Our findings show the therapeutic potential of apatinib for advanced HNSCC patients with multiple lines of chemotherapy, especially for patients with large neck masses.
Self-assembled multifunctional nanostructures for surface passivation and photon management in silicon photovoltaics
Authors: Hossain Mohammad Jobayer , Sun Mengdi , Doerk Gregory , Kik Pieter G. , Davis Kristopher O. 
Published: November 2021

Abstract
This work reports the fabrication and characterization of multifunctional, nanostructured passivation layers formed using a self-assembly process that provide both surface passivation and improved light trapping in crystalline silicon photovoltaic (PV) cells. Scalable block copolymer self-assembly and vapor phase infiltration processes are used to form arrays of aluminum oxide nanostructures (Al2O3) on crystalline silicon without substrate etching. The Al2O3 nanostructures are characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM), and spectroscopic ellipsometry. Injection-level dependent photoconductance measurements are used to determine the effective carrier lifetime of the samples to confirm the nanostructures successfully passivate the Si surface. Finite element method simulations and reflectance measurement show that the nanostructures increase the internal rear reflectance of the PV cell by suppressing the parasitic optical losses in the metal contact. An optimized morphology of the structures is identified for their potential use in PV cells as multifunctional materials providing surface passivation, photon management, and carrier transport pathways.
Imaging-based optical barcoding for relative humidity sensing based on meta-tip
Authors: Liu Yin , Li Xiaowei , Chen Yufeng , Geng Guangzhou , Li Junjie , Wang Yongtian , Huang Lingling 
Published: November 2021

Abstract
In a wide range of applications such as healthcare treatment, environmental monitoring, food processing and storage, and semiconductor chip manufacturing, relative humidity (RH) sensing is required. However, traditional fiber-optic humidity sensors face the challenges of miniaturization and indirectly obtaining humidity values. Here, we propose and demonstrate an optical barcode technique by cooperating with RH meta-tip, which can predict the humidity values directly. Such RH meta-tip is composed of fiber-optic sensor based on surface plasmon resonance (SPR) effect and graphene oxide film as humidity sensitizer. While SPR sensor is composed of multimode fiber (MMF) integrated with metallic metasurface. Dynamic time warping (DTW) algorithm is used to obtain the warp path distance (WPD) sequence between the measured reflection spectrum and the spectra of the precalibrated database. The distance sequence is transformed into a pseudo-color barcode, and the humidity value is corresponded to the lowest distance, which can be read by human eyes. The RH measurement depends on the collective changes of the reflection spectrum rather than tracking a single specific resonance peak/dip. This work can open up new doors to the development of a humidity sensor with direct RH recognition by human eyes.
The crystal structure of {N
1,N
2-bis[2,4-dimethyl-6-(4-(tert-butyl)phenyl)(phenyl)methyl]acenaphthylene-1,2-diimino-κ2
N, N′}-dibromido-nickel(II) – dichloromethane(1/2), C64H64Br2Cl4N2Ni
Authors: Guo Kun-Peng 
Published: November 2021

Abstract
C64H64Br2Cl4N2Ni, monoclinic, C2/c (no. 15), a = 31.9723(18) Å, b = 11.9826(6) Å, c = 18.4722(11) Å, β = 125.038(2)°, V = 5794.4(6) Å3, Z = 4, R

gt
(F) = 0.0536, wR

ref
(F
2) = 0.1640, T = 273.15 K.
Crystal structure of (E)-7-methoxy-2-((2-methoxypyridin-3-yl)methylene)-3,4-dihydronaphthalen-1 (2H)-one, C18H17NO3
Authors: Ma Guang-Qun , Zhao Feng-Lan , Meng Qing-Guo 
Published: November 2021

Abstract
C18H17NO3, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 7.4638(8) Å, b = 8.0392(8) Å, c = 12.6767(11) Å, α = 108.187(8)°, β = 94.029(7)°, γ = 95.071(8)°, V = 715.95(13) Å3, Z = 2, R

gt
(F) = 0.0573, wR

ref
(F
2) = 0.1460, T = 100.0(2) K.