bluuebunny/crossref_metadata_2025_split huggingface dataset:
Water Culture at the Sanctuary of Amphiaraos at Oropos: A Quantitative Reexamination of Three Inscriptions
Authors: Androvitsanea Anna 
Published: October 2021

Three 4th-century inscriptions found in situ at the Sanctuary of Amphiaraos at Oropos constitute an instance of ancient “open government data,” providing access to public information on planned and implemented building projects. The inscriptions document the construction of a drainage system and a bath complex in detail, as well as the rehabilitation of a fountain and two bath complexes. They discuss the scope of work, budgetary and time constraints, and responsible individual, providing valuable information about the topography of the site and the history of its development. The complexity and adaptation of the hydraulic system, part of the expansion and transformation of the sanctuary, offer new insights into the evolution of ancient hydraulic science and on the different techniques used to store and distribute water and to influence the micro-climate of a site and its experience by visitors.
Bathing Beauties. Hygiene, Hydrotherapy, and the Female Nude: An Early Hellenistic Bronze Case-Mirror from Elis
Authors: Stewart Andrew , Liston Maria A. 
Published: October 2021

A Greek bronze case-mirror showing four naked young women showering under a waterfall in a rocky landscape, discovered in a late 4th-century grave at Stafidokampos near the ancient city of Elis, and published by Xeni Arapoyanni in 1999, raises a number of questions about women’s health, hygiene, and personal care in early Hellenistic Greece. After remarks on the scene’s embossing or toreutic technique, its origins and typology are discussed and its participants identified with the aid of Pausanias, who visited the area around 170 CE. They are the Ionides, four nymphs worshiped at a healing spring that fed into the river Kytheros at Eleian Herakleia, about fifty stades from Olympia. Presumably this mirror was specially crafted to market to women seeking a cure there, and was bought by or for the occupant of the grave in which it was found. Analysis in July 2016 of the associated human remains revealed that they belonged to an adult female about 30-35 years old and a child about 10. The woman’s skeleton shows that she suffered from a chronic inflammatory joint disease, possibly rheumatoid arthritis. The resulting pain and swelling of her joints evidently drove her to the Ionides’ spring in search of a cure. At the very least, the warm water would have eased her joint pain and given her some relief from her symptoms.
Created at the Water’s Edge: Poetics and Politics in Greek Foundation Myths
Authors: Feldman Cecelia A. 
Published: October 2021

Stories are meaningful and the stories that a community tells about itself are particularly ripe with information. The foundation myths of many cities in the Mediterranean include a source of water or claim mythological ancestors that are progeny of local water sources. This paper takes as its focus the foundation myths of several Greek communities – Ephesos, Samos, and Halikarnassos – as a way to argue for the centrality of water, both in practical terms and for identity formation. The question remains, however, why the geographical feature included in these foundation myths is overwhelmingly a water source. These narratives could easily achieve the same purpose with the inclusion of a host of other distinguishing geographical features. I argue that including reference to local water sources in these foundation narratives connect to the practical but also the ideological importance of water for a community. In this paper I argue that the emphasis on local water sources, which was further emphasized in the visual and material record, expresses the centrality of water in the understanding of “place” and in the construction of civic identities.
Maternal and Infant Immune Repertoire Sequencing Analysis Identifies Distinct Ig and TCR Development in Term and Preterm Infants
Authors: Le Brian L , Sper Renan , Nielsen Sandra C A , Pineda Silvia , Nguyen Quoc-Hung , Lee Ji-Yeun , Boyd Scott D , MacKenzie Tippi C , Sirota Marina 
Published: October 2021

Abstract
Preterm labor (PTL) is the leading cause of neonatal morbidity and mortality worldwide. Whereas many studies have investigated the maternal immune responses that cause PTL, fetal immune cell activation has recently been raised as an important contributor to the pathogenesis of PTL. In this study, we analyzed lymphocyte receptor repertoires in maternal and cord blood from 14 term and 10 preterm deliveries, hypothesizing that the high prevalence of infection in patients with PTL may result in specific changes in the T cell and B cell repertoires. We analyzed TCR β-chain (TCR-β) and IgH diversity, CDR3 lengths, clonal sharing, and preferential usage of variable and joining gene segments. Both TCR-β and IgH repertoires had shorter CDR3s compared with those in maternal blood. In cord blood samples, we found that CDR3 lengths correlated with gestational age, with shorter CDR3s in preterm neonates suggesting a less developed repertoire. Preterm cord blood displayed preferential usage of a number of genes. In preterm pregnancies, we observed significantly higher prevalence of convergent clones between mother/baby pairs than in term pregnancies. Together, our results suggest the repertoire of preterm infants displays a combination of immature features and convergence with maternal TCR-β clones compared with that of term infants. The higher clonal convergence in PTL could represent mother and fetus both responding to a shared stimulus like an infection. These data provide a detailed analysis of the maternal–fetal immune repertoire in term and preterm patients and contribute to a better understanding of neonate immune repertoire development and potential changes associated with PTL.
Cutting Edge: Circulating Exosomes with COVID Spike Protein Are Induced by BNT162b2 (Pfizer–BioNTech) Vaccination prior to Development of Antibodies: A Novel Mechanism for Immune Activation by mRNA Vaccines
Authors: Bansal Sandhya , Perincheri Sudhir , Fleming Timothy , Poulson Christin , Tiffany Brian , Bremner Ross M , Mohanakumar Thalachallour 
Published: October 2021

Abstract
Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) causes severe acute respiratory syndrome. mRNA vaccines directed at the SARS-CoV-2 spike protein resulted in development of Abs and protective immunity. To determine the mechanism, we analyzed the kinetics of induction of circulating exosomes with SARS-CoV-2 spike protein and Ab following vaccination of healthy individuals. Results demonstrated induction of circulating exosomes expressing spike protein on day 14 after vaccination followed by Abs 14 d after the second dose. Exosomes with spike protein, Abs to SARS-CoV-2 spike, and T cells secreting IFN-γ and TNF-α increased following the booster dose. Transmission electron microscopy of exosomes also demonstrated spike protein Ags on their surface. Exosomes with spike protein and Abs decreased in parallel after four months. These results demonstrate an important role of circulating exosomes with spike protein for effective immunization following mRNA-based vaccination. This is further documented by induction of humoral and cellular immune responses in mice immunized with exosomes carrying spike protein.
Orthodontic curriculum in Saudi Arabia
Authors: Al-Gunaid Talat Hasan , Eshky Rawah Talal , Alnazzawi Ahmed Abdulkarem 
Published: October 2021

OBJECTIVES:
This study aimed to assess the perception of orthodontic staff members around clinical learning outcomes (LOs) of the undergraduate orthodontic curriculum with a focus on dental schools in Saudi Arabia.

MATERIALS AND METHODS:
Twenty-three LOs were formulated, all of which were associated with skills required in the undergraduate orthodontics course. Orthodontic staff members were invited to provide their opinion regarding the curriculum using a Likert scale, whereby participants could answer each question on a scale from “Strongly Agree” to “Strongly Disagree.”

RESULTS:
Sixty-one teaching staff members agreed to partake in this study. The highest level of agreement among the participants pertained to conducting systematic orthodontic intraoral and extraoral examinations (100%), followed by explaining causes for space loss (98.3%). The lowest level of agreement was regarding executing a treatment plan for non-skeletal cases (62.2%) followed by skills of fabrication and activation of removable appliances (77%). Around 67.1% of the academics refused to allow dental students to select and bond orthodontic brackets.

CONCLUSION:
It is time to amalgamate the objectives and create a unified national list of LOs for all orthodontic curriculums across the country without any distinction of knowledge or skills required at the undergraduate level.
Testről és nevelésről
Authors: Lanszki Anita 
Published: October 2021

A mozdulatok oktatásának története a neveléstörténet figyelemre méltó területe, melynek kutatási paradigmája társadalom- és kultúrtörténeti vizsgálódásokat és egzakt dokumentumelemzést is feltételez. A Simonetta Polenghi, Németh András és Tomáš Kasper szerkesztésében, 2021-ben megjelent impozáns tanulmánykötet széleskörű áttekintést nyújt a századfordulótól az 1950-es évekig tartó időszak oktatási irányzatairól. A kötet szerzői a korszak európai országainak testneveléssel és mozdulatművészettel kapcsolatos trendjeit izgalmas nézőpontokból mutatják be. A tanulmányok megvilágítják, hogyan befolyásolták a 20. század első felének közegészségügyi, eszmetörténeti, művészeti és pedagógiai irányzatai test fejlesztését célzó oktatáspolitikai törekvéseket.
A magyarországi táncszínházi nevelés
Authors: Kun Attila 
Published: October 2021

A tanulmány célja, hogy a magyarországi táncszínházi nevelési területén folyamatban lévő kutatás eddigi eredményeinek tükrében áttekintést adjon a hazai kortárs tánchoz köthető színházi nevelési célzatú tevékenységekről. A tanulmány számba veszi a részvételi táncszínházi nevelési programok hazai beágyazottságát a prózai színházi nevelési struktúra viszonylatában, valamint módszertani diverziójának történeti előzményeit, mindenkori finanszírozási formáit és aktivitásait.
Los retos de la Universidad Peruana en el contexto de la Globalización
Authors: Verónica Bazán Linares Magda , Pilar Gaona Portal Milagros del , Alberto Luis Grados Carlos , Lisseth Luna Acuña Maleyne , Ethel Peralta Roncal Liliana , Jiménez José Ángel Meneses 
Published: October 2021

La globalización es el fenómeno económico que impacta en diversas esferas de una sociedad, en las cuales genera numerosos cambios, siendo una de ellas el campo educativo. La educación, especialmente la universitaria ha tenido que adaptarse a estos cambios con el propósito de continuar brindando un servicio de acorde a las necesidades del mundo globalizado manteniendo su visión humanista, científica y tecnológica.
Las universidades peruanas sumándose a estos cambios asumieron el reto de la virtualización de sus sistemas de enseñanza aprendizaje, adaptando modelos pedagógicos, estrategias metodológicas y uso de recursos tecnológicos a las nuevas necesidades de una educación no presencial, en donde los docentes y estudiantes fortalecieron sus competencias digitales haciendo uso de diversos recursos tecnológicos disponibles en la web.
La UNAS al igual que las diferentes universidades nacionales e internacionales asumió el reto de una educación no presencial durante la emergencia sanitaria, este paso significó un cambio de su modelo pedagógico, adaptando la currícula académica al desarrollo de competencias digitales, al uso de estrategias, recursos y herramientas disponibles on line; todo ello a partir del análisis de sus procesos institucionales, administrativos, académicos y de investigación. Convirtiéndose así en ese ente dinamizador y de cambio que exige la globalización.

Globalization is economic phenomenon that impacts diversity spheres of a society, in which it generates numerous changes, one of them being educational field. Education, especially university education, has been adapted to these changes in order to continue providing a service in accordance with needs globalized world, maintaining humanistic, scientific and technological vision.
Peruvian universities, joining these changes, took on the challenge of virtualizing their teaching learning systems, adapting pedagogical models, methodological strategies and use of technological resources to new needs of virtual education, where teachers and students strengthened their skills making use various technological resources available on web.
UNAS like different national and international universities, has assumed the challenge of virtual education during health emergency, this step has been meant a change in its pedagogical model, adapting academic curriculum to development of digital skills, the use of strategies, resources and tools available online; all this from the analysis of its institutional, administrative, academic and research processes. Thus, becoming that dynamic and changing entity that globalization requires.
Resilience, fear of COVID-19 and their relationship with cognitive functioning and mood: a study on the administrative staff of the University of Western Macedonia, Greece
Authors: Flora Katerina , Georgiadou Triantafyllia , Megari Kalliopi , Grigoropoulos Iraklis , Chasiotis Vasilis 
Published: October 2021

Background: The present study examines the relationship between resilience, mood, fear for Covid-19, and cognitive functioning during pandemic Covid-19.
Methods: A cross-sectional web-based study was conducted from December 2020 to January 2021 among the administrative staff of the University of Western Macedonia, Greece. Data was collected using the Connor-Davidson Resilience Scale (CD-RISC), Depression, Anxiety, and Stress (DASS 21), fear of Covid-19 scales (FCV-19S), and Cognitive functioning self-assessment scale (CFSS). Univariate, bivariate, and multivariate analysis was performed using an independent Sample T-Test, Chi-Square Test, One-way ANOVA, Mann-Whitney U Test, Kruskal-Wallis H Test, Spearman's Rank-Order Correlations, Pearson product-moment correlations, and Simple Linear Regression. SPSS version 22 was used for data analysis and the statistical significance was considered at less than 0.05.
Results: Data of 88 university's administrative staff has undergone final analysis. Most of the respondents were females (78.4%), married (61.3%), middle-aged group (64.8%), held a post-graduate degree (56.8%) and 94.3% stated that they had not been sick with Covid-19. Our findings showed that the middle-aged group has statistically significantly higher fear on Covid-19 (P = 0.046), and more care of personal hygiene, stress (P = 0.040), than the young age group respectively. Women had a statistically significantly higher restriction to physical contact compared to men (P = 0.042), however, men had statistically significantly more trusted the results of clinical trials of Covid-19 vaccines than women (P = 0.039), respectively. There was statistically significant and negative correlation between Resilience (CD) and cognitive functioning (r = -0.412, n = 87, P < 0.001). Furthermore, the result of a simple linear regression showed that an increase of one in CD corresponded to a 0.287 decrease in cognitive functioning.
Conclusion: It is vital to continue monitoring the psychological and cognitive effects of the Covid-19 pandemic.
Karakteristik Marshall Campuran Aspal AC-WC Menggunakan filler Spent Bleaching Earth Sebagai Pengganti Abu Batu
Authors: Kurniawan Wawan 
Published: October 2021

Indonesia’s road crackdown commonly USES a flexible crackdown that a main ingredient on asphalt. One of the tools used in subthanizing aggregates with spent bleaching earth (SBE) replacing the filler SBE into teh mix of asphalt is predicted to enhance resiliencs SBE isa solid waste produced by the plants’s biofuel refinery, which included the exictence of B2 on this study aims to find out how much marshall’s characteristics affect the AC-WC asphalt replace the filler with SBE on at the first stage of testing got an optimum asphalt level next filler replacement will be done with SBE as big 0%, 25%, 50%, 75%, 100% and the result met the spesifications at SBE level 25%, with this research this waste of B2 could be used replace the filler in variations 25%
Pemanfaatan Limbah Plastik Untuk Pembuatan Paving block
Authors: Sudarno Sudarno 
Published: October 2021

Limbah plastik yang tadinya hanya sebagai barang buangan kotor, berbau dan banyak menimbulkan penyakit serta mencemari lingkungan, sebenarnya dapat dimanfaatkan menjadi berbagai macam bahan konstruksi ringan yang bermanfaat dalam kehidupan manusia. Hal ini karena selain dapat dimanfaatkan dari segi teknis, bahan olahan dari saMPah plastik juga memiliki nilai ekonomi yang tinggi. Penelitian ini bertujuan untuk mengurangi polusi limbah plastik yang mencemari lingkungan hidup dan mendapatkan campuran terbaik pada limbah plastik untuk pembuatan paving block, mengetahui besarnya nilai kuat tekan dan lentur paving block plastik dan agregat kasar, dengan membandingkan biaya per antara paving dari limbah plastik dan paving normal. Penelitian ini dilaksanakan di Laboratorium Uji Bahan, Jurusan Teknik Sipil Politeknik Negeri Manado. Metode yang digunakan dalam penelitian ini adalah experimental dengan simulasi pembebanan sebagai uji kuat tekan dan kuat lentur. Model paving block yang diteliti berupa paving block dengan bentuk persegi panjang berdimensi benda uji lebar = 10cm, tebal = 8cm dan panjang = 20cm. Hasil menunjukan bahwa paving normal mempunyai nilai mutu yang lebih kecil dari paving block dari limbah plastik yang diteliti, juga dari segi biaya paving block dari limbah plastik lebih murah dari pada paving block normal.
Môi trường trầm tích châu thổ và đá cát kết chứa dầu khí bể Nam Côn Sơn
Authors: Khac Tan Tran , Thuong San Ngo , Manh Toan Nguyen , Hai Dang Pham , Thi Thu Trang Hoang , Tho Tran 
Published: October 2021

Đường bờ biển là đới chuyển tiếp giữa môi trường trầm tích lục địa và môi trường trầm tích biển. Khu vực này chịu tác động của cả lục địa và biển. Châu thổ ven biển là kết quả quá trình trầm tích ở cửa các hệ thống sông; hình thái, địa tầng của châu thổ phụ thuộc vào các yếu tố khác nhau như trầm tích từ các sông vận chuyển đến, khu vực tiêu nước, hình thể địa hình dòng chảy vận chuyển ra biển và các yếu tố tác động của biển tái phân bố lại các vật liệu trầm tích ở đường bờ. Ngoài ra, vật liệu trầm tích còn có thể được cung cấp đến các đới ven biển dọc theo bờ từ nguồn ngoài khơi, không liên quan đến sông ngòi.
Các loại đá cát kết trầm tích môi trường châu thổ là đá chứa dầu khí chính trong địa tầng trầm tích ở nhiều nơi trên thế giới. Có 4 kiểu tướng và môi trường trầm tích được minh giải theo mẫu và biểu đồ vật lý giếng khoan ở các giếng khoan Lô 07/03 và Lô 04-1, bể Nam Côn Sơn. Các tướng này được mô tả tuần tự là đồng bằng châu thổ (delta plain), trước châu thổ (delta front), đồng bằng ven biển và tiền châu thổ (pro-delta).
A new ASAP Scoring System and Risk Table to predict second prostate biopsy outcomes
Authors: Ediz Caner , Akan Serkan , Kaya Terzi Neslihan , Ihvan Aysenur 
Published: October 2021

IntroductionThis study aimed to discuss the necessity of a second prostate biopsy in patients with atypical small acinar proliferation (ASAP) and to develop a scoring system and risk table to be used as new criteria for a second biopsy.Material and methodsThe study reviewed the data of 2,845 patients; who underwent transrectal ultrasonography-guided prostate biopsy in the period between January 2008 and May 2019. A total of 128 patients with ASAP were included in the study. The tPSA, fPSA, f/tPSA, and PSA-Density levels before the first and second biopsies and changes in the measured levels between the values obtained before the first and the second biopsies were recorded. “ASAP Scoring System and risk table” (ASS-RT) was evaluated before the second biopsy.ResultsThe mean age of 128 patients with ASAP was 62.9±7.8 years. The ASS-RT scores of prostate cancer patients were significantly higher compared to patients without prostate cancer (p: 0.001). In the ROC curve analysis of ASS-RT, the area under the curve was 0.804 and the standard error was 0.04. The area under the ROC curve was significantly higher than 0.5 (p:0.001). The cut-off point of ASS-RT scores in diagnosing cancer was ≥ 7 with 60.8% sensitivity and 80.5% specificityConclusionsThe cut-off value of 7 determined for the ASS-RT score in this study suggests that patients with ASS-RT scores of ≥7 should undergo a second prostate biopsy. We think that there may be no need for a second biopsy if the ASS-RT score is <7, especially for low-risk patients.
Effectiveness of honey therapy combined with photobiomodulation
in the treatment of oral lichen planus: a randomized placebo-controlled trial
Authors: Fathy Samhan Ahmed , Mohamed Abdelhalim Nermeen 
Published: October 2021

IntroductionOral lichen planus (OLP) is a chronic inflammatory disorder that commonly occurs in the skin and mucosa of the oral cavity. This study aimed to evaluate the effectiveness of honey therapy (HT) combined with photobiomodulation (PBM) in the treatment of OLP.MethodsThe study involved 46 patients aged 40–55 (48.15 ± 6.28) years with erosive or atrophic OLP in the buccal mucosa. They were randomly allocated to 2 groups: study group (HT/PBM) (<i>n</i> = 23) and placebo group (golden syrup/PBM) (<i>n</i> = 23). Both groups received PBM (980-nm gallium-aluminium arsenide) with a power output of 0.3 W, 3 sessions per week for 4 weeks. At the same time, each patient in the study group was instructed to apply pure commercial honey, while patients in the placebo group were instructed to apply golden syrup, during the whole treatment period. All patients were assessed at baseline and after the treatment via visual analogue scale (VAS), oral function scores, and evaluation of OLP clinical manifestation.ResultsPatients in both groups were homogeneous in terms of age and gender, as well as the 3 clinical assessment values (<i>p</i> > 0.05) before the treatment. In the study group, post-treatment results regarding VAS (<i>p</i> < 0.0001), oral function scores (<i>p</i> < 0.0001), and OLP clinical manifestation (<i>p</i> < 0.05) were statistically significantly better than those in the placebo group.ConclusionsHT combined with PBM reduced pain and improved OLP clinical manifestation and oral function scores in patients with OLP.