bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring SMEs' behavioral intentions of participating in platform-based innovation ecosystems
Authors: Wei Fenfen , Feng Nanping , Xue Jinqi , Zhao Ruxiang , Yang Shanlin 
Published: August 2021

PurposeSmall- and-medium sized enterprises (SMEs) significantly contribute to the success of platform-based innovation ecosystems (PIEs). However, less is known about their behaviors and behavioral intentions (BIs) toward participating in PIEs. Considering that SMEs' BIs directly influence their behaviors and reveal the underlying logic of their behaviors, this study, therefore, focuses on SMEs' BIs and explores the antecedents to reveal the rational effects on BIs of the participation.Design/methodology/approachAn extended framework is proposed to understand SMEs' BIs toward the participation and empirically tested with data from a sample of 189 Chinese SMEs based on partial least squares structural equation modeling (PLS-SEM).FindingsThe results show that (1) the framework has a good fit in the context of PIEs and a large predictability of SMEs' BIs toward the participation; (2) as expected, SMEs' BIs are directly positively affected by their attitudes (ATTs), subjective norms (SNs) and platform leaders (PLs), while indirectly positively influenced by perceived usefulness (PU) and ease and negatively influenced by perceived risks (PRs) via mediation effects and (3) surprisingly, BIs are directly negatively affected by platforms probably because of the potential collaborative risks based on platforms.Originality/valueThis study enriches PIE literature by focusing on complementors and proposing a framework of SMEs' BI toward joining PIEs, and it also expands the application of BI–behavior theories in the context of PIEs by offering a BI–behavior perspective to analyze the rational logic of SMEs' behaviors of participating to PIEs. Practically, the main findings not only benefit SMEs to better understand their BIs and to make a wise choice toward the participation, but provide implications for PLs to proactively design interventions for attracting SMEs’ complementors.
Comparative effect of short-term credit granted to agriculture on agricultural added value in the West African countries
Authors: Oloukoi Laurent 
Published: August 2021

PurposeThe paper analyzes the response of agricultural value added to credit and real interest rate shocks in the West African Economic and Monetary Union (WAEMU) and make a short-term comparative effect analysis of credit granted to the agricultural sector on agricultural value added among member countries.Design/methodology/approachFirst, in order to estimate impulse response functions (IRFs) and study shocks, a panel VAR model is used. Second the paper uses an autoregressive distributed lag (ARDL) model with the associated error correction model to make a comparative analysis of the effect of agricultural credit on agricultural value added in the WAEMU.FindingsResults shows that: (1) credit stimulates agricultural value added only in the medium and long term; (2) in the case of WAEMU, credit only becomes a means of lifting the constraint of capital underutilization after three years; (3) short-term credit granted to agriculture in WAEMU has a weak and differentiated effect on agricultural value added from one country to another.Practical implicationsIt is imperative to implement a policy of lowering real short-term interest rates. Moreover, a monetary policy that favors direct financing of agriculture to the detriment of that oriented toward market financing is to be prioritized.Originality/valueThe originality of this paper is that it makes the link between macroeconomics and agriculture. It shows how the monetary instrument can be manipulated to improve the performance of agriculture. Actually, in WAEMU, the financing of agriculture is provided by the market. This paper proposes a new approach which is direct financing. The paper offers possibilities for the coordination of agricultural policies in the WAEMU.
The impact of economic growth, trade openness and manufacturing on CO2 emissions in India: an autoregressive distributive lag (ARDL) bounds test approach
Authors: Karedla Yaswanth , Mishra Rohit , Patel Nikunj 
Published: August 2021

PurposeThe purpose of this study is to examine the impact of economic growth, trade openness and manufacturing on CO2 emissions in India.Design/methodology/approachThe study employed autoregressive distributive lag (ARDL) bounds test approach and uses CO2 emissions, trade, manufacturing and GDP per capita to examine the relationship using an annual time series data from World Development Indicators during 1971 to 2016.FindingsResults depict that there exists a long-run relationship between CO2 emissions and other variables. Trade openness significantly reduces CO2 emissions, whereas manufacturing and GDP have a significant and positive impact on CO2 in the long run.Research limitations/implicationsThe findings of the study contribute to the body of knowledge by providing new evidence on the relationship between developmental metrics and the environment. These findings are critical for policymakers and regulatory bodies to focus on economic development without jeopardizing environmental degradation.Practical implicationsIn order to keep its commitment to sustainability, India needs to develop policies that encourage cleaner production methods and establishment of non-polluting industries. Simultaneously, it must disincentivize industries that emit CO2 by policy frameworks such as carbon taxes, pollution taxes or green taxes.Originality/valueNone of studies examine at how these environmental factors interact in India. Kilavuz and Dogan (2020) used the same variables, but their scope was limited to Turkey. As a result, the study is the first to examine this relationship for India, contributing to the body of knowledge on economic growth, manufacturing, trade openness and environmental concerns.
How do changes in family role status impact employees? An empirical investigation
Authors: Perrigino Matthew B. , Kossek Ellen Ernst , Thompson Rebecca J. , Bodner Todd 
Published: August 2021

PurposeDespite the proliferation of work–family research, a thorough understanding of family role status changes (e.g. the gaining of elder or child caregiving responsibilities) remain under-theorized and under-examined. The purpose of this paper is to conceptualize various forms of family role status changes and examine the ways in which these changes influence various employee outcomes.Design/methodology/approachData were collected as part of the work–family health study. Using a longitudinal, three-wave study with two-time lags of 6 months (n = 151 family role status changes; n = 392 individuals with family role stability), this study uses one-way analysis of variance to compare mean differences across groups and multilevel modeling to examine the predictive effects of family role status changes.FindingsOverall, experiences of employees undergoing a family role status change did not differ significantly from employees whose family role status remained stable over the same 12-month period. Separation/divorce predicted higher levels of family-to-work conflict.Originality/valueThe work raises important considerations for organizational science and human resource policy research to better understand the substantive effects of family role status changes on employee well-being.
Examining the integration of continuous improvement and strategic planning in select pharmaceutical companies in India: a case study
Authors: Kaur Harjit , Kaushik Sanjay 
Published: August 2021

PurposeThe objective of the study is to examine the extent to which pharmaceutical companies in India rely on traditional planning approaches rather than the new learning approach to strategic planning. In addition to that, the study also seeks to examine the perceived ability of the pharmaceutical companies in India to integrate continuous improvement goals and product quality into the overall strategic planning and success in implementing total quality management (TQM) programs examined through three particular continuous improvement mindsets.Design/methodology/approachThe study collected data from select pharmaceutical companies in India through survey technique using a standardized questionnaire through online mode. A descriptive statistical analysis is performed to examine the extent of integration of strategic planning and continuous improvement in the select pharmaceutical companies in India.FindingsThe results of the study indicate that pharmaceutical companies in India still rely greatly on traditional planning methods for strategic planning. However, a shift is also observed toward adoption of best practice management and modern strategic management techniques. The study also demonstrates that continuous improvement goals and strategies are included into the corporate strategic planning.Research limitations/implicationsThe study employs only descriptive statistics, and no hypotheses are generated in the study because the objective is not to generalize the findings. The process of formulating quality goals and integrating them with strategy is typical to any company. Therefore, the findings cannot be generalized. The findings of the study do not given any insights into the strategic quality management process due to online mode of data collection. Also, the focus on the study is on the internal management of quality in an organization and factors in the external environment or in the value chain outside the firm, influencing strategic management of quality are beyond the scope of present study.Practical implicationsConsidering the significance of quality of products, an understanding of the link between quality and strategic goals helps the managers in pharmaceutical industry to align the strategic planning goals with quality goals ensuring that the entire organization moves in same strategic direction.Originality/valueThe strong focus quality in pharmaceutical industry in India has given impetus to development of well-managed quality programs on the shop-floor to remain competitive and survive in the highly competitive global markets. However, no such study is conducted so far to understand the extent to which continuous improvement or TQM practices are integrated into strategic planning in the pharmaceutical companies in India.
Disrupted macrophage metabolic reprogramming in aged soleus muscle during early recovery following disuse atrophy
Authors: Fix Dennis K. , Ekiz H. Atakan , Petrocelli Jonathan J. , Mckenzie Alec M. , Mahmassani Ziad S. , O'Connell Ryan M. , Drummond Micah J. 
Published: August 2021

AbstractAged skeletal muscle is characterized by poor muscle recovery following disuse coinciding with an impaired muscle pro‐inflammatory macrophage response. Macrophage inflammatory status is regulated by its metabolic state, but little is understood of macrophage metabolism and its relation to macrophage inflammation in the context of muscle recovery and aging. Therefore, the purpose of this study was to thoroughly characterize macrophage metabolism and inflammation in aged muscle during early recovery following disuse atrophy using single cell transcriptomics and functional assays. Young (4–5 months) and old (20–22 months) male C57BL/6 mice underwent 14 days of hindlimb unloading followed by 4 days of ambulatory recovery. CD45+ cells were isolated from solei muscles and analyzed using 10x Genomics single cell RNA sequencing. We found that aged pro‐inflammatory macrophage clusters were characterized with an impaired inflammatory and glycolytic transcriptome, and this dysregulation was accompanied by a suppression of HIF‐1α and its immediate downstream target, Glut1. As a follow‐up, bone marrow‐derived macrophages were isolated from a separate cohort of young and old mice at 4‐d recovery and were polarized to a pro‐inflammatory phenotype and used for glycolysis stress test, phagocytosis activity assay, and targeted GC‐MS metabolomics. Aged bone marrow‐derived pro‐inflammatory macrophages were characterized with impaired glycolysis and phagocytosis function, decreased succinate and an accumulation of glycolytic metabolic intermediates overall supporting reduced glycolytic flux and macrophage function. Our results indicate that the metabolic reprograming and function of aged skeletal muscle pro‐inflammatory macrophages are dysfunctional during early recovery from disuse atrophy possibly attributing to attenuated regrowth.
Group clinical supervision for allied health professionals
Authors: Gardner Marcus , McKinstry Carol , Perrin Byron 
Published: August 2021

AbstractObjectiveTo evaluate a group clinical supervision program for allied health professionals in a regional health service.DesignThis study used a mixed‐methods design including a cross‐sectional, quantitative survey of group clinical supervision participants and a focus group of facilitators.SettingA large regional health service in Victoria, providing hospital, community and mental health services.ParticipantsAllied health professionals and managers employed at the health service.InterventionsGroup clinical supervision, based on a critical reflection model, was implemented in 3 settings.Main outcome measureThe Clinical Supervision Evaluation Questionnaire was administered to group clinical supervision participants, with additional open‐ended questions included. The Clinical Supervision Evaluation Questionnaire tool consists of 3 subscales relating to the purpose, process and impact of group clinical supervision. A focus group was used to capture the perspectives of group clinical supervision facilitators.ResultsFifteen survey responses were received. The overall Clinical Supervision Evaluation Questionnaire score was 56.53 (standard deviation 7.66). Scores for the Process Subscale were higher than the Purpose and Impact subscales. Themes from the open‐ended survey questions included the following: value of multiple perspectives, opportunities for reflection, peer support and group process and structure. Themes from group facilitators’ focus group included the following: need for group clinical supervision, value of facilitator training and support, and sustainability.ConclusionGroup clinical supervision was perceived to be effective, enhancing reflection, learning and peer support. Organisational support, facilitator training, group structure and planning for sustainability were identified as critical factors for success. Interprofessional and cross‐organisational models of group clinical supervision are strategies that could help address issues relating to access to quality clinical supervision for rural allied health professionals.
Validity of cycloheximide chylomicron flow blocking method for the evaluation of lymphatic transport of drugs
Authors: Ryšánek Pavel , Grus Tomáš , Lukáč Peter , Kozlík Petr , Křížek Tomáš , Pozniak Jiří , Roušarová Jaroslava , Královičová Jana , Kutinová Canová Nikolina , Boleslavská Tereza , Bosák Jan , Štěpánek František , Šíma Martin , Slanař Ondřej 
Published: August 2021

Background and purposeLymphatic transport of drugs after oral administration is an important mechanism for absorption of highly lipophilic compounds. Direct measurement in lymph duct cannulated animals is the gold standard method, but non‐invasive cycloheximide chylomicron flow blocking method has gained popularity recently. However, concerns about its reliability have been raised. The aim of this work was to investigate the validity of cycloheximide chylomicron flow blocking method for the evaluation of lymphatic transport using model compounds with high to very high lipophilicity, that is, abiraterone and cinacalcet.Experimental approachSeries of pharmacokinetic studies were conducted with abiraterone acetate and cinacalcet hydrochloride after enteral/intravenous administration to intact, lymph duct cannulated and/or cycloheximide pre‐treated rats.Key resultsMean total absolute oral bioavailability of abiraterone and cinacalcet was 7.0% and 28.7%, respectively. There was a large and significant overestimation of the lymphatic transport extent by the cycloheximide method. Mean relative lymphatic bioavailability of abiraterone and cinacalcet in cycloheximide method was 28‐fold and 3‐fold higher than in cannulation method, respectively.Conclusion and implicationsCycloheximide chylomicron flow blocking method did not provide reliable results on lymphatic absorption and substantially overestimated lymphatic transport for both molecules, that is, abiraterone and cinacalcet. This non‐invasive method should not be used for the assessment of lymphatic transport and previously obtained data should be critically revised.
An international assessment of the adoption of enhanced recovery after surgery (ERAS®) principles across colorectal units in 2019–2020
Authors:   ESCP Enhanced Recovery Collaborating Group
Published: August 2021

AbstractAimThe Enhanced Recovery After Surgery (ERAS®) Society guidelines aim to standardize perioperative care in colorectal surgery via 25 principles. We aimed to assess the variation in uptake of these principles across an international network of colorectal units.MethodAn online survey was circulated amongst European Society of Coloproctology members in 2019–2020. For each ERAS principle, respondents were asked to score how frequently the principle was implemented in their hospital, from 1 (‘rarely’) to 4 (‘always’). Respondents were also asked to recall whether practice had changed since 2017. Subgroup analyses based on hospital characteristics were conducted.ResultsOf hospitals approached, 58% responded to the survey (195/335), with 296 individual responses (multiple responses were received from some hospitals). The majority were European (163/195, 83.6%). Overall, respondents indicated they ‘most often’ or ‘always’ adhered to most individual ERAS principles (18/25, 72%). Variability in the uptake of principles was reported, with universal uptake of some principles (e.g., prophylactic antibiotics; early mobilization) and inconsistency from ‘rarely’ to ‘always’ in others (e.g., no nasogastric intubation; no preoperative fasting and carbohydrate drinks). In alignment with 2018 ERAS guideline updates, adherence to principles for prehabilitation, managing anaemia and postoperative nutrition appears to have increased since 2017.ConclusionsUptake of ERAS principles varied across hospitals, and not all 25 principles were equally adhered to. Whilst some principles exhibited a high level of acceptance, others had a wide variability in uptake indicative of controversy or barriers to uptake. Further research into specific principles is required to improve ERAS implementation.
Lung transplantation outcomes after crossing low‐level donor specific antibodies without planned augmented immunosuppression
Authors: Courtwright Andrew M. , Kamoun Malek , Diamond Joshua M. , Kearns Jane , Ahya Vivek N. , Christie Jason D. , Clausen Emily , Hadjiliadis Denis , Patel Namrata , Salgado Juan C. , Cevasco Marisa , Cantu Edward E. , Crespo Maria M. , Bermudez Christian A. 
Published: August 2021

AbstractIt is unknown whether some donor specific antibodies (DSA) can be crossed at the time of lung transplant without desensitization or augmented induction immunosuppression. This study assessed whether crossing low‐level pre‐transplant DSA (defined as mean fluorescence intensity [MFI] 1000–6000) without augmented immunosuppression is associated with worse retransplant‐free or chronic lung allograft dysfunction (CLAD)‐free survival. Of the 458 included recipients, low‐level pre‐transplant DSA was crossed in 39 (8.6%) patients. The median follow‐up time was 2.2 years. There were 15 (38.5%) patients with Class I DSA and 24 (61.5%) with Class II DSA. There was no difference in adjusted overall retransplant‐free survival between recipients where pre‐transplant DSA was and was not crossed (HR: .98 [95% CI = .49–1.99], P = .96). There was also no difference in CLAD‐free survival (HR: .71 [95% CI = .38–1.33], P = .28). There was no difference in Grade 3 PGD at 72 h (OR: 1.13 [95% CI = .52–2.48], P = .75) or definite or probable AMR (HR: 2.22 [95% CI = .64–7.61], P = .21). Lung transplantation in the presence of low‐level DSA without planned augmented immunosuppression is not associated with worse overall or CLAD‐free survival among recipients with intermediate‐term follow‐up.
The generalist parasitoid Nasonia vitripennis shows more behavioural plasticity in host preference than its three specialist sister species
Authors: Kalyanaraman Dhevi , Gadau Jürgen , Lammers Mark 
Published: August 2021

AbstractHost preference is an important behaviour in parasitoid females as they must choose suitable hosts for their offspring. Preference includes location, recognition and acceptance of hosts. Both genetic and environmental factors can affect all those stages. Here, we focus on two factors (rearing history and experience) affecting host preference in the parasitoid wasp genus Nasonia (Hymenoptera: Chalcidoidea: Pteromalidae: Pteromalinae), which harbours both a host generalist (N. vitripennis) and several closely related specialists (N. giraulti, N. longicornis and N. oneida). We tested whether Nasonia females prefer the host that they developed in by rearing them on two different host species (Lucilia sericata and Calliphora vomitoria) for over 10 generations before testing them for their host preference. We then tested whether experience changes host preference by allowing the females to feed and oviposit on either host species before testing their host preference. Only the generalist N. vitripennis showed behavioural plasticity as the effect of rearing history on host preference was overruled by their experience with a different host species. In contrast, the three specialist species were not affected by long‐term rearing history and only shifted their host preference based on experience. In all four known Nasonia species, individual adult experience modulated host recognition, acceptance and preference.