bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of Nonlinear Pressure-Flow Characteristics of a Spring-Loaded Pressure Relief Valve Based on Computational Fluid Dynamics Simulation
Authors: Wu Chengshuo , Li Shiyang , Li Qianqian , Wu Peng , Huang Bin , Wu Dazhuan 
Published: April 2021

Abstract
In this study, the nonlinear pressure-flow characteristics of a spring-loaded pressure relief valve (PRV), which is used in the automotive fuel supply system for pressure control is analyzed, and its characteristics are improved by means of geometrical modifications of the valve structure. Given the complexity of the coupling mechanism between the valve internal flow characteristics and spring system, a quasi-steady computational fluid dynamics (CFD) method is introduced to predict the nonlinear pressure-flow characteristic curve of the valve and the accuracy is validated by experimental data. The total hydraulic force on the valve spool and diaphragm are divided into three parts according to the loading position and the correlation between the internal flow characteristics, hydraulic force, and pressure-flow characteristics of the valve are explained by CFD analysis and visualization. The results show that the quasi-steady CFD method can accurately predict the trends of the valve nonlinear pressure-flow characteristic curve, which is mainly determined by the hydraulic force produced in the middle chamber of the valve. When the valve opening reaches a certain value, a main vortex would be formed in the middle chamber and lead to the sudden increase of hydraulic force which causes the fluctuation of the pressure-flow characteristic curve of the valve. It is also found that the toggle point for the flow regimes seen in the valve is affected by the geometric structure of the middle chamber and the pressure-flow characteristics can be improved by the round corner size modification.
Application of the OMERACT Grey-scale Ultrasound Scoring System for salivary glands in a single-centre cohort of patients with suspected Sjögren’s syndrome
Authors: Fana Viktoria , Dohn Uffe M , Krabbe Simon , Terslev Lene 
Published: April 2021

AimTo describe salivary gland involvement in patients suspected of Sjögren’s syndrome (SS) using the OMERACT Ultrasound Scoring System for SS. Next, using different ultrasound cut-offs, to assess the performance of the scoring system for diagnosis and fulfilment of 2016 ACR/EULAR SS classification criteria.MethodsAll patients referred to our department with a suspicion of SS in a 12-month period were included. All underwent grey-scale ultrasound of the parotid and submandibular glands prior to clinical examination, Schirmer’s test, unstimulated salivary flow, blood samples including autoantibody analysis. Labial biopsy was performed according to clinicians’ judgement. Images of the four glands were scored 0–3 according to the scoring system and a consensus score was obtained using a developed ultrasound atlas.ResultsOf the 134 patients included in the analysis, 43 were diagnosed with primary SS (pSS) and all fulfilled the 2016 American College of Rheumatology (ACR)/EULAR classification criteria. More patients with pSS compared with non-pSS had score ≥2 in at least one gland (72% vs 13%; p<0.001). In patients with score ≥2 in any gland, significantly more had positive autoantibodies, sialometry, Schirmer’s test and positive labial biopsy compared with those with scores ≤1. The best ultrasound cut-off value for diagnosing pSS was ≥1 gland with a score ≥2 (sensitivity=0.72, specificity=0.91).ConclusionThe OMERACT Ultrasound Scoring System showed good sensitivity (0.72) and excellent specificity (0.91) for fulfilling 2016 ACR/EULAR criteria using cut-off score >2 in at least one gland. Our data supports the use of ultrasound for diagnosing pSS and supports incorporation of ultrasound in the classification criteria.
Production and electromagnetic decay of hyperons: a feasibility study with HADES as a phase-0 experiment at FAIR
Authors: Adamczewski-Musch J. , Belyaev A. , Blanco A. , Blume C. , Charlotte C. , Borisenko D. S. , Charlotte C. , Chlad L. , Chudoba P. , Ciepał I. , Derichs A. , Dittert D. , Dreyer J. , Esmail W. , Fateev O. , Fonte P. , Friese J. , Fröhlich I. , Förtsch J. , Galatyuk T. , Georgadze I. , Golosov O. , Golubeva M. , Greifenhagen R. , Grunwald M. , Grzonka D. , Guber F. , Gumberidze M. , Harabasz S. , Heinz T. , Heybeck B. , Höhne C. , Holona M. ,   (HADES collaboration and PANDA@HADES collaboration), Holzmann R. , Huck H. , Ierusalimov A. , Imre M. , Ivashkin A. , Kämpfer B. , Kampert K-H. , Kardan B. , Kedych V. , Khomyakov V. , Koenig I. , Koenig W. , Kohls M. , Kornakov G. , Kornas F. , Kotte R. , Kozela A. , Kozlov V. , Kres I. , Kuboś J. , Kugler A. , Kulessa P. , Ladygin V. , Lalik R. , Le Galliard C. , Lebedev A. , Lebedev S. , Linev S. , Lopes L. , Lorenz M. , Lykasov G. , Malige A. , Markert J. , Matulewicz T. , Michel J. , Morozov S. , Müntz C. , Naumann L. , Nowakowski K. , Orfanitsky S. , Otto J. -H. , Patel V. , Pauly C. , Pechenov V. , Pechenova O. , Perez Andrade G. , Petukhov O. , Pfeifer D. , Piasecki K. , Pietraszko J. , Prozorov A. , Przygoda W. , Pysz K. , Ramstein B. , Rathod N. , Regina J. , Reshetin A. , Reznikov S. , Rieger J. T. , Ritman J. , Rodriguez-Ramos P. , Rost A. , Rustamov A. , Salabura P. , Saraiva J. , Schild N. , Schwab E. , Schönning K. , Scozzi F. , Seck F. , Selyuzhenkov I. , Serdyuk V. , Shabanov A. , Singh U. , Smyrski J. , Sobiella M. , Spies S. , Strikhanov M. , Ströbele H. , Stroth J. , Sumara K. , Svoboda O. , Szala M. , Szewczyk J. , Taranenko A. , Tlusty P. , Traxler M. , Wagner V. , Wasiluk M. , Weber A. A. , Wendisch C. , Wintz P. , Włoch B. , Zbroszczyk H. P. , Zherebzova E. , Zhilin A. , Zinchenko A. , Zumbruch P. 
Published: April 2021

AbstractA feasibility study has been performed in order to investigate the performance of the HADES detector to measure the electromagnetic decays of the hyperon resonances$$\Sigma (1385)^{0}$$Σ(1385)0, $$\Lambda (1405)$$Λ(1405) and$$\Lambda (1520)$$Λ(1520) as well as the production of double strange baryon systems$$\Xi ^{-}$$Ξ- and $$\Lambda $$Λ$$\Lambda $$Λ in p + p reactions at a beam kinetic energy of$$4.5\,{\mathrm{GeV}}$$4.5GeV. The existing HADES detector will be upgraded by a new Forward Detector, which extends the detector acceptance into a range of polar angles that plays a crucial role for these investigations. The analysis of each channel is preceded by a consideration of the production cross-sections. Afterwards the expected signal count rates using a target consisting of either liquid hydrogen or polyethylene are summarized.
Quantum cosmology with dynamical vacuum in a minimal-length scenario
Authors: Gusson M. F. , Gonçalves A. Oakes O. , Furtado R. G. , Fabris J. C. , Nogueira J. A. 
Published: April 2021

AbstractIn this work, we consider effects of the dynamical vacuum in quantum cosmology in presence of a minimum length introduced by the GUP (generalized uncertainty principle) related to the modified commutation relation$$[{\hat{X}},{\hat{P}}] := \frac{i\hbar }{ 1 - \beta {\hat{P}}^2 }$$[X^,P^]:=iħ1-βP^2. We determine the wave function of the Universe$$ \psi _{qp}(\xi ,t)$$ψqp(ξ,t), which is solution of the modified Wheeler–DeWitt equation in the representation of the quasi-position space, in the limit where the scale factor of the Universe is small. Although$$\psi _{qp}(\xi ,t)$$ψqp(ξ,t)is a physically acceptable state it is not a realizable state of the Universe because$$ \psi _{qp}(\xi ,t)$$ψqp(ξ,t)has infinite norm, as in the ordinary case with no minimal length.
The waste rock of the Touro copper deposit in Galicia, Spain: challenges for its environmental characterization
Authors: Meuzelaar Tom , Núñez-Fernández Pablo , Martín-Izard Agustín , Arias-Prieto Daniel , Díaz-Riopa Fernando 
Published: April 2021

Characterization of metamorphic rocks to evaluate waste material acid rock drainage potential is particularly challenging as commonly used laboratory methods can result in its significant underprediction. Static tests were conducted for over 300 samples from the Touro copper project and indicate that carbon-based methods frequently overestimate acid neutralization potential due to the presence of both graphite and manganese–iron carbonates. The Modified Sobek method more accurately accounts for the buffering capacity of carbonates and does not account for graphite, although aluminosilicate dissolution kinetics need to be evaluated in the context of sulfide oxidation rates. Historic sulfur assays for the project relied on methods insufficient to fully digest metamorphosed sulfides and required correction. The more aggressive Leco method provides accurate sulfur estimates and has now been adopted for the project.
Static test metrics such as the net neutralization potential or neutralization potential ratio, therefore, can give misleading results when incorrect characterization methods are employed. Such metrics should be considered as screening level, used with caution, and complemented with careful field and laboratory kinetic tests. Preliminary humidity cell testing of five Touro samples suggests that terminal pH values for cells that have become acidic closely match predicted net acid generation (NAG) pH values. The NAG pH test avoids some of the challenges associated with sulfur and carbon predictions in metamorphic rocks as it directly buffers sulfide oxidation acidity with available material neutralization potential. As such, NAG pH has been adopted as the accepted project metric for segregating acid-generating from non-acid-generating waste.

Supplementary material:
All Touro project static and kinetic test data are available at
https://doi.org/10.6084/m9.figshare.c.5389948

Thematic collection:
This article is part of the Hydrochemistry related to exploration and environmental issues collection available at:
https://www.lyellcollection.org/cc/hydrochemistry-related-to-exploration-and-environmental-issues
Confidence Intervals for Stochastic Arithmetic
Authors: Sohier Devan , Castro Pablo De Oliveira , Févotte François , Lathuilière Bruno , Petit Eric , Jamond Olivier 
Published: April 2021

Quantifying errors and losses due to the use of Floating-point (FP) calculations in industrial scientific computing codes is an important part of the Verification, Validation, and Uncertainty Quantification process. Stochastic Arithmetic is one way to model and estimate FP losses of accuracy, which scales well to large, industrial codes. It exists in different flavors, such as CESTAC or MCA, implemented in various tools such as CADNA, Verificarlo, or Verrou. These methodologies and tools are based on the idea that FP losses of accuracy can be modeled via randomness. Therefore, they share the same need to perform a statistical analysis of programs results to estimate the significance of the results.
In this article, we propose a framework to perform a solid statistical analysis of Stochastic Arithmetic. This framework unifies all existing definitions of the number of significant digits (CESTAC and MCA), and also proposes a new quantity of interest: the number of digits contributing to the accuracy of the results. Sound confidence intervals are provided for all estimators, both in the case of normally distributed results, and in the general case. The use of this framework is demonstrated by two case studies of industrial codes: Europlexus and code_aster.
Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy
Authors: Goli Rahul , Li Jian , Brandimarto Jeff , Levine Lisa D. , Riis Valerie , McAfee Quentin , DePalma Steven , Haghighi Alireza , Seidman J. G. , Seidman Christine E. , Jacoby Daniel , Macones George , Judge Daniel P. , Rana Sarosh , Margulies Kenneth B. , Cappola Thomas P. , Alharethi Rami , Damp Julie , Hsich Eileen , Elkayam Uri , Sheppard Richard , Alexis Jeffrey D. , Boehmer John , Kamiya Chizuko , Gustafsson Finn , Damm Peter , Ersbøll Anne S. , Goland Sorel , Hilfiker-Kleiner Denise , McNamara Dennis M. ,   The IMAC-2 and IPAC Investigators, Arany Zolt 
Published: April 2021

Background:

Peripartum cardiomyopathy (PPCM) occurs in ≈1:2000 deliveries in the United States and worldwide. The genetic underpinnings of PPCM remain poorly defined. Approximately 10% of women with PPCM harbor truncating variants in
TTN
(TTNtvs). Whether mutations in other genes can predispose to PPCM is not known. It is also not known if the presence of TTNtvs predicts clinical presentation or outcomes. Nor is it known if the prevalence of TTNtvs differs in women with PPCM and preeclampsia, the strongest risk factor for PPCM.

Methods:

Women with PPCM were retrospectively identified from several US and international academic centers, and clinical information and DNA samples were acquired. Next-generation sequencing was performed on 67 genes, including
TTN
, and evaluated for burden of truncating and missense variants. The impact of TTNtvs on the severity of clinical presentation, and on clinical outcomes, was evaluated.

Results:

Four hundred sixty-nine women met inclusion criteria. Of the women with PPCM, 10.4% bore TTNtvs (odds ratio=9.4 compared with 1.2% in the reference population; Bonferroni-corrected
P
[
P
*]=1.2×10
–46
). We additionally identified overrepresentation of truncating variants in FLNC (odds ratio=24.8,
P
*=7.0×10
–8
), DSP (odds ratio=14.9,
P
*=1.0×10
–8
), and BAG3 (odds ratio=53.1,
P
*=0.02), genes not previously associated with PPCM. This profile is highly similar to that found in nonischemic dilated cardiomyopathy. Women with TTNtvs had lower left ventricular ejection fraction on presentation than did women without TTNtvs (23.5% versus 29%,
P
=2.5×10
–4
), but did not differ significantly in timing of presentation after delivery, in prevalence of preeclampsia, or in rates of clinical recovery.

Conclusions:
This study provides the first extensive genetic and phenotypic landscape of PPCM and demonstrates that predisposition to heart failure is an important risk factor for PPCM. The work reveals a degree of genetic similarity between PPCM and dilated cardiomyopathy, suggesting that gene-specific therapeutic approaches being developed for dilated cardiomyopathy may also apply to PPCM, and that approaches to genetic testing in PPCM should mirror those taken in dilated cardiomyopathy. Last, the clarification of genotype/phenotype associations has important implications for genetic counseling.
Ischemic Stroke With Atrial Fibrillation: Characteristics and Time Trends 2006 to 2017 in the Dijon Stroke Registry
Authors: Gabet Amélie , Guenancia Charles , Duloquin Gauthier , Olié Valérie , Béjot Yannick 
Published: April 2021

Background and Purpose:
Because of the aging population, an increase in the prevalence of atrial fibrillation (AF) is currently observed, thus leading to a rise in AF-related ischemic stroke (IS). We analyzed the current prevalence of AF among patients with IS, their characteristics, and temporal trends from 2006 to 2017 in the population-based Dijon Stroke Registry.

Methods:
We used data from the Dijon Stroke Registry, an ongoing population-based study that records all cases of acute stroke among residents of the city of Dijon. All patients with IS between 2006 and 2017 were included. Previous AF was defined if it was mentioned in the medical file before stroke and newly diagnosed AF if it was diagnosed during the diagnostic workup of patients with acute stroke.

Results:

During the period 2014 to 2017, among the 796 patients with IS recorded in the Dijon Stroke Registry, 239 (30.0%) had AF, of whom 79 (9.9% of total patients with IS) had newly diagnosed AF, and 98 (12.3%) had previous AF treated with oral anticoagulants. Patients with IS with AF had more disabilities and a higher initial severity according to the National Institutes of Health Stroke Scale compared with those without AF. The age-adjusted prevalence of AF in patients with IS increased between 2006 and 2017 (+9% per time period), with an important increase in men aged 65 to 74 years (+81%) and women aged ≥85 years (+24%), and a significant decrease in women aged 65 to 74 years (−39%). The use of oral anticoagulant treatment in previous AF patients increased between 2006 and 2009 and 2014 and 2017 (29.3% to 61.3%,
P
<0.0001). However, 37.5% of patients with previous AF and CHADS
2
score ≥2 were not treated with OAC.

Conclusions:
The increase in AF prevalence in patients with IS could be related to a better diagnosis of this condition. The underuse of oral anticoagulation treatment was still observed.
Centrum Semiovale Perivascular Space and Amyloid Deposition in Spontaneous Intracerebral Hemorrhage
Authors: Tsai Hsin-Hsi , Pasi Marco , Tsai Li-Kai , Huang Chi-Ching , Chen Ya-Fang , Lee Bo-Ching , Yen Ruoh-Fang , Gurol M. Edip , Jeng Jiann-Shing 
Published: April 2021

Background and Purpose:
We explored whether high-degree magnetic resonance imaging–visible perivascular spaces in centrum semiovale (CSO) are more prevalent in cerebral amyloid angiopathy (CAA) than hypertensive small vessel disease and their relationship to brain amyloid retention in patients with primary intracerebral hemorrhage (ICH).

Methods:
One hundred and eight spontaneous ICH patients who underwent magnetic resonance imaging and Pittsburgh compound B were enrolled. Topography and severity of enlarged perivascular spaces were compared between CAA-related ICH (CAA-ICH) and hypertensive small vessel disease–related ICH (non-CAA ICH). Clinical and image characteristics associated with high-degree perivascular spaces were evaluated in univariate and multivariable analyses. Univariate and multivariable models were performed to evaluate associations between the severity of perivascular spaces in CSO and amyloid retention in CAA-ICH and non–CAA-ICH cases.

Results:

Patients with CAA-ICH (n=29) and non–CAA-ICH (n=79) had similar prevalence of high-degree perivascular spaces in CSO (44.8% versus 36.7%;
P
=0.507) and in basal ganglia (34.5% versus 51.9%;
P
=0.131). High-degree perivascular spaces in CSO were independently associated with the presence of lobar microbleed (odds ratio, 3.0 [95% CI, 1.1–8.0];
P
=0.032). The amyloid retention was higher in those with high-degree than those with low-degree CSO-perivascular spaces in CAA-ICH (global Pittsburgh compound B standardized uptake value ratio, 1.55 [1.33–1.61] versus 1.13 [1.01–1.48];
P
=0.003) but not in non–CAA-ICH. In CAA-ICH, the association between cerebral amyloid retention and the degree of perivascular spaces in CSO remained significant after adjustment for age and lobar microbleed number (
P
=0.004).

Conclusions:
Although high-degree magnetic resonance imaging–visible perivascular spaces are equally prevalent between CAA-ICH and non–CAA-ICH in the Asian cohort, the severity of magnetic resonance imaging–visible CSO-perivascular spaces may be an indicator of higher brain amyloid deposition in patients with CAA-ICH.
The Globalization of the “New Wave”
Authors: Leonova Olga 
Published: April 2021

Abstract
Globalization in the XXI century is an objective phenomenon that manifests itself as a complex system with many nonlinear relationships between its subjects and objects. Globalization of the “new wave” has a number of specific characteristics and trends. They have led to the emergence of negative consequences and unexpected results of globalization. These tendencies do not presuppose the process of de-globalization, but they are a sign of the passage from one model of globalization to another, from the monocentric structure of the world to the polycentric one, which affords ground for its nomination as “non-global globalization”. The article compares the approaches and achievements of Russian and Western globalistics.
The Intertextual Rhetoric of the Apostrophe to Zion (11QPsa XXII, 1–15)
Authors: Kim Hyun Woo 
Published: April 2021

Abstract
Considerable agreement has existed concerning the intertextual relations between the Apostrophe to Zion (Ap Zion) and Third Isaiah. But I propose to reread Ap Zion as a literary and theological response to the most famous lament over Zion, exemplified in the book of Lamentations. The common acrostic feature and leitmotif of Zion shared by Lamentations and Ap Zion clearly reflect the latter’s deliberate attention to the former. In this reconsideration, I argue that the much-acclaimed intertextuality between Ap Zion and Third Isaiah is the consequence of the pre-established Isaianic inner-biblical allusion (Second Isaiah) to Lamentations. To expand on this proposal, the paper will explore the multilayered intertextuality between Lam 2, Isa 49, and Ap Zion through classifying their lexical, thematic, structural, and theological associations.
Dawud al-Fatani’s Thoughts on Marriage in Īḍāḥu l-Bāb li-Murīdi l-Nikāḥ bi-l-Ṣawāb
Authors: Noor Zanariah , Lee Nazirah 
Published: April 2021

Abstract
This paper examines Sheikh Dawud al-Fatani’s Īḍāḥu l-bāb li-murīdi l-nikāḥ bi-l-ṣawāb (“Explanation of the chapter for the one who desires a good marriage”), which outlines his understanding and mastery of the jurisprudence of Islamic family law. Al-Fatani is a renowned nineteenth-century Malay Muslim scholar, and his work is widely referred to in Islamic education institutions in the region. A close scrutiny of Īḍāḥu l-bāb offers a profound understanding of nineteenth-century Malay Muslims’ view of the institution of marriage. The foci of this paper include the general concept of marriage in Islam; guidelines on spouse selection; the obligations of both husband and wife; and the law on inter-religious marriage. In summary, al-Fatani shows that marriage requires a meticulous consideration of all parties involved; after all, family is a paramount social unit that needs to be preserved to ensure stability in the development of a society.
Islamic Heritage and Morisco Identity
Authors: Debasa Ana María Carballeira 
Published: April 2021

Abstract
Through an assessment of the data recorded in two books of habices (Span., libros de habices – inventories of goods from Islamic pious endowments) dated 1527 and 1530, this study examines the situation of Morisco women in the Alpujarra, a rural area of Granada, just three decades after the forced conversion of the Muslim population to Christianity. Various aspects of the economic and social position of these women are explored, paying particular attention to their participation in the legal framework related to property ownership and the transfer of their possessions in the form of bequests. Although the study focuses primarily on the Morisco period, its most immediate precedent, Islamic and Mudéjar Granada, is not forgotten.
Between City, King, and Empire: Will the Real “Lady of Byblos” Please Stand Up?
Authors: Stahl Michael J. 
Published: April 2021

Abstract
Who was the goddess known anciently as the “Lady of Byblos”? Typically, scholars have tried to answer this question by identifying the goddess’s “true” proper name. By contrast, this article emphasizes the goddess’s primary identification by the city of Byblos as a social-political community in order to analyze the Lady of Byblos’s role in shaping Late Bronze Age Byblos’s political landscape, which included imperial, royal, and collective modes of governance. The goddess’s place in Byblos’s political-religious economy thus serves as a fruitful case study for better conceptualizing through the lens of religion the complex range of potential interactions in the ancient world between centralizing and decentralizing political forces as parts of a single social-political system. In this way, the Lady of Byblos may “stand up” not only as an integral member of Byblos’s social order and religious life, but also as an example of the fundamental role that deities played in shaping ancient political realities.