bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Presença de um Núcleo de Atendimento Educacional e sua Contribuição para a Atenuação de Dificuldades de Leitura e Escrita / The Presence of an Educational Center and its Contribution to the Attenuation of Difficulties in Reading and Writing
Authors: Borges Silas Baleeiro , Almeida Maria Antonieta Pereira Tigre 
Published: November 2021

Resumo: O presente artigo tem por finalidade a busca por estratégias que possam atenuar os déficits de leitura e escrita da rede municipal de educação no município de Aracatu – Bahia. Os objetivos da pesquisa são: Investigar as etapas de construção de um Núcleo de Atendimento Educacional Especializado no município de Aracatu – Ba; Identificar as práticas educativas de inclusão necessárias a um espaço escolar inclusivo; Analisar práticas positivas que poderão ser usadas para contribuir no bom desempenho em leitura e escrita. A metodologia utilizada foi pesquisa de campo com levantamento de informações de professores e coordenadores que atuam nas escolas no ano de 2021, coletando informações e as transformando em dados qualitativos e quantitativos. Conclui-se que o núcleo será um suporte para que professores e famílias entendam como lidarem com situação de crianças com diagnósticos e a maneira como serão incluídas sob um novo olhar de um espaço escolar inclusivo. Palavras – chave: Atendimento Educacional; Educação; Inclusão; Leitura/Escrita. Abstract: The purpose of this article is to search for strategies that can attenuate reading and writing deficits in the municipal education network in the city of Aracatu – Bahia. The research objectives are: To investigate the stages of construction of a Specialized Educational Service Center in the city of Aracatu – Ba; Identifying the educational practices of inclusion necessary for an inclusive school space; Analyze positive practices that can be used to contribute to good performance in reading and writing. The methodology used was field research with a survey of information from teachers and coordinators who work in schools in 2021, collecting information and transforming it into qualitative and quantitative data. It is concluded that the nucleus will be a support for teachers and families to understand how to deal with the situation of children with diagnoses and how they will be included under a new perspective of an inclusive school space.Keywords: Educational Service; Education; Inclusion; Reading/Writing.
Electroencephalogram patterns with the presence of an unknown musical stimulus
Authors: Costa Ana Clara Pereira Resende da , Davi Ramos Camila , Ferreira-Jorge Amanda Rosa , Campos Marcos , Destro-Filho João-Batista , Frosi Rosa Pedro 
Published: November 2021

The cerebral activity presents different behaviors in different situations and levels of consciousness, especially under musical stimulation. Signals of the central nervous system may disclose bioelectrical patterns, since listening to rhythmic sequences activates specific brain areas. In this paper, we analyze 42 neurologically normal Brazilian individuals, submitted to musical stimulation based on a procedure consisting of three different steps, during which the volunteer is kept with closed eyes. The first step is associated with the preliminary control silence period, without any stimulus, as the volunteer remains at rest. The second step consisted of unknown music stimulation. Finally, the third step involves post-music rest. Quantitative signal analysis computes the power spectrum time variations. Results point out stronger changes in gamma and high gamma waves (30 – 100 Hz). Even though the clinical rhythms (0 – 30 Hz) change throughout the whole period of the experiment, quantitative differences at gamma and high gamma bands are remarkably greater. Particularly, when comparing the initial silent period and the final post-stimulation silent one, bioelectrical differences are only highlighted by gamma and high gamma rhythms. In consequence, this paper points out that the EEG analysis of cognitive issues related to musical perception cannot disregard gamma and high gamma waves.
A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol
Authors: Izumi Yukitoshi , Cashikar Anil G. , Krishnan Kathiresan , Paul Steven M. , Covey Douglas F. , Mennerick Steven J. , Zorumski Charles F. 
Published: November 2021

Inflammatory cells, including macrophages and microglia, synthesize and release the oxysterol 25-hydroxycholesterol (25HC), which has antiviral and immunomodulatory properties. Here, we examined the effects of lipopolysaccharide (LPS), an activator of innate immunity, on 25HC production in microglia, and the effects of LPS and 25HC on CA1 hippocampal synaptic plasticity and learning. In primary microglia, LPS markedly increases the expression of cholesterol 25-hydroxylase (Ch25h), the key enzyme involved in 25HC synthesis, and increases the levels of secreted 25HC. Wild-type microglia produced higher levels of 25HC thanCh25hknock-out (KO) microglia with or without LPS. LPS treatment also disrupts long-term potentiation (LTP) in hippocampal slices via induction of a form of NMDA receptor-dependent metaplasticity. The inhibitory effects of LPS on LTP were mimicked by exogenous 25HC, and were not observed in slices fromCh25hKO mice.In vivo, LPS treatment also disrupts LTP and inhibits one-trial learning in wild-type mice, but notCh25hKO mice. These results demonstrate that the oxysterol 25HC is a key modulator of synaptic plasticity and memory under proinflammatory stimuli.SIGNIFICANCE STATEMENTNeuroinflammation is thought to contribute to cognitive impairment in multiple neuropsychiatric illnesses. In this study, we found that a proinflammatory stimulus, LPS, disrupts hippocampal LTP via a metaplastic mechanism. The effects of LPS on LTP are mimicked by the oxysterol 25-hydroxycholesterol (25HC), an immune mediator synthesized in brain microglia. Effects of LPS on both synaptic plasticity and one-trial inhibitory avoidance learning are eliminated in mice deficient in Ch25h (cholesterol 25-hydroxylase), the primary enzyme responsible for endogenous 25HC synthesis. Thus, these results indicate that 25HC is a key mediator of the effects of an inflammatory stimulus on hippocampal function and open new potential avenues to overcome the effects of neuroinflammation on brain function.
Delirium in the NICU: A Point Prevalence Study
Authors: Siegel Elana J. , Groves Alan M. , Silver Gabrielle , Hojsak Joanne , Lim C. Anthoney , Traube Chani 
Published: November 2021

OBJECTIVES
Delirium is a well-described complication of critical illness, with occurrence rates of &gt;25% in the PICU, and associated morbidity. Infants in the NICU are likely at risk. There have been no previous screening studies to quantify delirium rates in the neonatal population. We hypothesized that delirium was prevalent in term neonates in the NICU. In this pilot study, our objective was to estimate prevalence using a validated pediatric delirium screening tool, which has not yet been tested in NICUs.

METHODS
In this point prevalence study, all term or term-corrected infants admitted to the NICU on designated study days were screened for delirium using the Cornell Assessment of Pediatric Delirium.

RESULTS
A total of 149 infants were eligible for screening over 8 study days. A total of 147 (98.6%) were successfully screened with the Cornell Assessment of Pediatric Delirium. Overall, 22.4% (n = 33) screened positive for delirium. Delirium was more commonly detected in children on invasive mechanical ventilation (67% vs 17%, P &lt; .01) and those with underlying neurologic disorders (64% vs 13%, P &lt; .01). A multivariate logistic regression revealed that neurologic disability and mechanical ventilation were both independently associated with a positive delirium screen (aOR: 12.3, CI: 4.5–33.6 and aOR: 9.3, CI: 2.5–34.6, respectively).

CONCLUSIONS
Our results indicate that delirium likely occurs frequently in term-equivalent infants in the NICU. Further research is necessary to establish feasibility, validity, and interrater reliability of delirium screening in this population.
Melatonin Administration Patterns for Pediatric Inpatients in a Tertiary Children’s Hospital
Authors: Procaccini David E. , Kudchadkar Sapna R. 
Published: November 2021

OBJECTIVES
Melatonin has been trialed with reported increasing use for sleep dysregulation and prevention of ICU delirium in critically ill adults; however, reports of use in hospitalized pediatric patients are limited. We anecdotally observed an increase in prescribing of melatonin in our tertiary care children’s hospital and therefore aimed to retrospectively characterize prescribing practices over time.

METHODS
Melatonin dispensing data over a 4-year time frame were extracted. Melatonin doses were categorized as being either ICU or non-ICU administered and dosed during daytime versus nighttime, respectively. Descriptive statistics were used to characterize patients who were administered melatonin, dosing information, and quantitative change in annual melatonin orders between areas. The comparison of daytime versus nighttime melatonin administrations and ratio of administrations between ICU and non-ICU areas for each study year were compared via χ2 test.

RESULTS
Administration of melatonin increased 246.2% between years 1 and 3, with a shift from predominance in ICU to non-ICU areas over the study period (P &lt; .0001). The average dosing varied by age, with the most frequent dose being 5 mg (28.3%), predominantly in patients ≥12 years of age. Ninety-eight percent (n = 9434) of doses were scheduled for nighttime administration, suggesting an indication of sleep regulation. There were significantly more daytime administrations of melatonin in non-ICU areas (P &lt; .0001).

CONCLUSIONS
Prescribing of melatonin for pediatric inpatients has increased substantially over a 4-year period, despite limited research on dosing, in this single-center. Further research is needed to determine best practices for melatonin prescribing for hospitalized children.
OSMANLI’DAN CUMHURİYET’E AYDINTEPE’DE İDARİ YAPI VE NÜFUS
Authors: GÖKTAŞ Serdar 
Published: November 2021

Günümüzde Bayburt Vilayeti’nin ilçelerinden biri olan Aydıntepe (Hart), coğrafi konum itibariyle Doğu Karadeniz Bölgesi içerisinde yer almaktadır. Kuzey ve kuzeybatıdan Trabzon ve Gümüşhane, doğu ve güneyden Bayburt ile çevrelenen Hart Ovası ile Soğanlı sıradağlarından oluşan Aydıntepe ve çevresi, ilk çağlardan bu yana birçok kültür ve medeniyetin etki alanına girmiştir. Selçuklular öncülüğünde Türklerin Anadolu’da ilk yerleştiği coğrafyalardan biri olan Aydıntepe, Osmanlı Devleti’nin Bayburt ve çevresini fethiyle birlikte kesin olarak Türk-İslam egemenliğine girmiştir.
Aydıntepe, Osmanlı yönetimi altına girdikten sonra köy hüviyetiyle idari bünye içerisinde yer almıştır. XIX. yüzyıl’da ise yapılan idari düzenlemeyle birlikte Bayburt Kazası’na bağlı bir nahiye durumuna getirilmiştir. Bu çalışmada Osmanlı Devleti’nin son dönemi ve Cumhuriyetin ilk yıllarında idari bünyede nahiye olarak yer alan Aydıntepe’nin idari yapısı ve nüfus özellikleri çevresinde yaşanan olaylar da göz önüne alınarak değerlendirilmeye çalışılacaktır.
Osteological studies of skull base neurovascular area in reference to infratemporal approach to skull basec
Authors: Sharma Harsh 
Published: November 2021

Surgical approaches to the lateral skull base often lead to tearing of vessels and piecemeal removal of the tumour. This study is aimed to delineate exact relationship of the various foramina at the lateral skull base. The coronal dimensions of the jugular foramina are larger as compared to sagittal with right sided dominance also noticed in the case of carotid canal. The width of “Keel” separating the carotid and jugular foramina normally varies from 0.4 to1.4 centimetres and may not always suggest the erosion of the foramen of skull base scans, unless the erosion is associated with irregularity or demineralization the thickness of this keel really depends upon relative size of the vessels and location of foramina. Area between stylomastoid foramen, carotid canal and jugular foramen is roughly wedge shaped. The angle subtended by carotid and jugular at the stylomastoid foramen is about 36.84whereas the location of stylomastoid foramen and internal carotid axis pose an angle of 83:16. The angle subtended by stylomastoid and jugular at carotid on an average 59:31. The space between these structures is measured to be 0.642centimetres which can be verified on tomograms. By using these measurements, the precise location of the upper end of the vessels could be predicted, whereas the superior stump could be clamped with minimal exposure of the skull base and identification and location of the last four cranial nerves is found out. This could avoid injuries and subsequent morbidity while carrying out surgery in this region.
The Interrater and Intrarater Reliability of the Preterm Infant Oral Feeding Readiness Assessment Scale
Authors: kamran Faride , Sagheb Setare , Aghajanzade Mashid , Ebadi Abbas , Faryadras Yaser , Khatoonabadi Ahmad Reza 
Published: November 2021

Introduction: One of the most challenging decisions is to assess the preterm infant’s transition from tube feeding to oral feeding. Thus, we require a reliable tool for determining the time to start oral feeding. This study aimed to measure the interrater and intrarater reliability of the Preterm Infant Oral Feeding Readiness Assessment scale (PIOFRA).
Materials and Methods: This study was an observational, cross-sectional study. The study participants were preterm infants who had been hospitalized in the Neonatal Intensive Care Unit of Shariati Hospital affiliated to Tehran University of Medical Sciences, between December 2017 and February 2018. The inclusion criteria were absence of neurological and gastrointestinal disorders or major congenital anomalies, Apgar score 3 or more in the first 1 minute, and 5 or more in the first 5 minutes. The exclusion criteria included family’s unwillingness to participate in the study, infant’s death, or a sudden change that affects neonates’ nutritional status, like cerebral hemorrhage or intestinal problems.
Results: The interrater and intrarater reliability of the total PIOFRA scale was good Intraclass Correlation Coefficients (ICC˃0.75). The interrater and intrarater reliability of most items were good and excellent, with weighted kappa more than 0.50, with the exception of lip posture and especially stress sign, with weighted kappa less than 0.40.
Conclusion: Generally, most items of the PIOFRA scale had acceptable interrater and intrarater reliability. Also, the interrater and intrarater reliabilities of the total POFRAs score was good.
Redes sociales: el carnaval, el mito y el héroe
Authors: Müller Maria Sara , Daraio Vanina 
Published: November 2021

En el presente documento intentaremos no recurrir a determinismos, ya sean apocalípticos o integrados (Eco, 2004), sino que apelaremos a generar nuevas lecturas y preguntas desde una perspectiva crítica. De esta forma, nos proponemos abordar -en torno a las redes sociales- algunas concepciones teóricas sobre la figura del carnaval y la máscara, como también, desarrollar articulaciones en torno a la noción de exposición y del mito del héroe para repensar la participación ciudadana en la red. Transversalmente, se intentarán evidenciar las posibles tensiones en relación a la mercantilización de la cotidianeidad, a través de la instauración de necesidades, el consumo incesante y la manipulación subjetiva que subyace en ciertas estrategias del mercado vía redes sociales, intensificadas más aún en épocas de COVID-19. La máscara y los personajes que encarnan se materializan como analizadores que permiten visualizar aquello que podría estar detrás, lo oculto, y asimismo, posibilitan distinguir entre –lo que aquí denominamos- las identidades inventadas (usuarios) y las identidades construidas históricamente, aquellas que nos nombran y nos dan pertenencia en una genealogía (el nombre propio). En el complejo ordenamiento social y simbólico que producen las redes, entendemos que existen expresiones de múltiples violencias: de género, ambiental, económica, psicológica, violencias sobre los derechos de grupos, sobre los valores colectivos. Es decir, bajo la lógica de la reproducción social de las desigualdades, para que haya héroes debe haber caídos.
La política migratoria de Trump y el acuerdo México-Estados Unidos: ¿Suficientes para el resguardo de la dignidad migratoria?
Authors: Salazar Urbina Daniel Stefano 
Published: November 2021

Desde épocas anteriores, México y Estados Unidos se sumergieron en un enfrentamiento que comprendió una variedad de causas. Ejemplos de esta afirmación lo constituyen políticas comerciales, de seguridad, migratorias, entre otras. Precisamente, uno de los aspectos que acentuó las rencillas entre los países mencionados, durante los últimos años, ha sido la disyuntiva relativa a los intentos de uniformizar las reglas para establecer un procedimiento migratorio seguro, transparente, no diferenciador y garante de los derechos humanos inherentes a todo migrante centroamericano. Al margen de que se suscribió un acuerdo migratorio entre México y Estados Unidos (la Declaración Conjunta) con el propósito de coadyuvar a aliviar el dilema anterior, no debe olvidarse que tal instrumento fue la respuesta a una rígida política migratoria dirigida por Donald Trump que afectó gravemente lo que se conoce como la dignidad migratoria de los individuos centroamericanos (propiedad humana que desprende el respeto e igual consideración que debe propenderse en favor de los migrantes para con el resto de la sociedad). De esta forma, el objetivo del presente trabajo es determinar la forma en que la irrestricta política migratoria norteamericana degradó la dignidad migratoria, a fin de comprobar si la estructuración de la Declaración Conjunta entre México y Estados Unidos constituyó una herramienta suficiente e idónea para aliviar los problemas que afectaban el tránsito migratorio centroamericano y, sobretodo, la dignidad migratoria.
PARTISIPASI PETANI TERHADAP PROGRAM REHABILITASI LAHAN REHAB KAWASAN MERU BETIRI DI DESA WONOASRI KECAMATAN TEMPUREJO KABUPATEN JEMBER
Authors: Firmana Charistandi , Widjayanthi Lenny 
Published: November 2021

of the Republic of Indonesia and is located in Jember Regency. Meru Betiri National Park (TNMB) is a conservation area that functions as a life support system which also acts as a means of supporting research, knowledge and education as well as supporting agricultural cultivation, recreation, and tourism and is directly adjacent to the village of Wonoasri, which is the fostered village of the Park. Meru Betiri National. Wonoasri Village was appointed as TNMB's target village because of its location which is one of the supporting villages for the conservation area. This study to study (1) the reasons why farmers participated in the land rehabilitstion program for rehabilitation land in the meru betiri area in Wonoasri Village, Tempurejo District, Jember Regency, (2) the participation process that occurred in the land rehabilitation program for the Meru Betiri area in Wonoasri Village, Tempurejo District, Jember Regency. The determination of the research area was carried out deliberately (purposive method). The research used qualitative method. research area used was Wonoasri Village, Tempurejo District, Jember Regency. The method of determining information in research that uses done purposively is selected with certain considerations and goals. The results showed that: (1) rehab farmers participate in the rehabilitation program for rehab land to conserve forests again, (2) Rehab farmers are directly involved in the planning process to evaluate economic benefits.
Keywords: Taman Nasional Meru Betiri, Wonoasri, Land Rehabilitation
Making the Computation of Approximations of Invariant Measures and Its Attractors for IFS and GIFS, Through the Deterministic Algorithm, Tractable
Authors: Cunha Rudnei Dias da , Oliveira Elismar R. 
Published: November 2021

Abstract

We present algorithms to compute approximations of invariant measures and its attractors for IFS and GIFS, using the deterministic algorithm in a tractable way, with code optimization strategies and use of data structures and search algorithms. The results show that these algorithms allow the use of these (G)IFS in a reasonable running time.
Explore Upper Limits of Bone Mineral Content And Density In Humans: A Study On Japanese Collegiate Sumo Wrestlers
Authors: Midorikawa Taishi , Torii Suguru , Ohta Megumi , Sakamoto Shizuo 
Published: November 2021

Abstract
The purpose of this study was to explore the upper limit of total bone mineral content (BMC, kg) and bone mineral density (BMD, g/cm2) in humans by estimating body composition of Sumo wrestlers. A total of 54 male college Sumo wrestlers were recruited for the study and assigned to 2 groups according to body weight (middleweight, 85-115 kg, n = 23 and heavyweight, >115 kg, n = 31). BMC, BMD, fat mass and lean soft tissue mass (LSTM) were measured using dual-energy X-ray absorptiometry (DXA) for the total and appendicular regions. Heavyweight Sumo wrestlers had significantly greater body weight, fat mass, and LSTM compared to middleweight Sumo wrestlers. Mean total BMC was significantly larger in heavyweight than middleweight Sumo wrestlers, respectively (The highest value was 4.16 kg.). Total BMD was significantly higher in heavyweight compared to middleweight Sumo wrestlers (The highest value was 1.59 g/cm2.), and was significantly correlated with body weight, but not with fat mass and LSTM. Based on the present and previous studies, the upper limit of total BMC and BMD in humans with 150 kg bodyweight might be around 5.0 kg and 1.60 g/cm2.
LaCl3 Treatment Improves the Agrobacterium-mediated Immature Embryo Genetic Transformation Efficiency in Maize
Authors: Liu Shengnan , Shi Yunlu , Guo Yan , Lu minhui 
Published: November 2021

Abstract
Agrobacterium

mediated genetic transformation of immature embryo plays an important auxiliary role in the study of gene function and molecular breeding in maize. However, the relatively low genetic transformation efficiency is still the bottleneck of the application of this method, especially in commercial scale production application. In this study, we found that pretreatment of immature embryos with LaCl 3 , a Ca 2+ channel blocker, could improve the infection efficiency of Agrobacterium tumefaciens , increase the proportion of resistant calluses, obtain more positive regenerated plantlets, and finally improve the transformation efficiency in maize. This optimization provides a new direction for improving the efficiency of plant genetic transformation mediated by Agrobacterium tumefaciens .