bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changing the face of academic skills workshops
Authors: Mansfield Sheryl 
Published: March 2021

The flipped approach offers flexibility in the way students learn and was adopted within Learning Development workshops to improve academic skills. Academic skills are predominantly taught using passive content, however the flipped approach looks to change the emphasis and provide active opportunities to understand taught knowledge. The sessions were delivered alongside self-paced, online, asynchronous content to scaffold academic skills and feed-forward guidance to inform summative assessment preparation. The objective was to assess the effectiveness of the flipped approach in delivering academic skills. A cohort of 50 first year students completed three face-to-face academic skills sessions together with the asynchronous content. Each were themed to develop different academic skills using subject specific examples. Attendance data was collected and a survey was used to evaluate the asynchronous content and measure the self-perceived academic confidence levels of students. To measure the success of the flipped approach this data was analysed together with the number of attempts at each e-tivity and the formative and summative grades. Results demonstrated those who attended two or more sessions (57.7% +/- 1.43) had a significantly higher summative score (p=0.041) than those who attended 1 or less (51.7% +/- 2.73). The summative grades and the number of attempts at the asynchronous content demonstrated a positive linear relationship for e-tivity 1 to 3. Overall the academic confidence improved in nearly a third of all students for each e-tivity and 17 students (54.8%) stated that they preferred the flipped approach in developing their academic skills. This emphasises that the flipped approach is an effective method to improve summative grades and deliver academic skills.
REGISTRATION ON THE WEBSITE OF THE MEDIA AND REQUIREMENTS FOR PERSONAL DATA IN RUSSIAN LEGISLATION
Authors: Ивлиев П.В. 
Published: March 2021

Аннотация. В статье рассматриваются нормы российского законодательства, регламентирующие правовые аспекты работы с персональными данными. Освещены термины сопутствующие персональным данным, исследуются актуальные проблемы работы средств массовой информации с персональными данными. Затрагиваются некоторые особенности разрешения споров относительно незаконного использования персональных данных.
Annotation. The article examines the norms of Russian legislation that regulate the legal aspects of working with personal data. The terms related to personal data are highlighted; the actual problems of the work of the media with personal data are investigated. Some features of dispute resolution regarding the illegal use of personal data are touched upon.
LEGAL CULTURE AND ITS ROLE IN A LEGAL STATE
Authors: Логинов С.Н. , Филимонов Д.Г. 
Published: March 2021

Аннотация. В статье дается характеристика содержания понятий «правовая культура» и «правовое государство», выделяются особенности взаимоотношения этих понятий между собой. Констатируется отсутствие единого мнения исследователей по вопросу содержания и функций правовой культуры, рассматриваются ряд ее определений. Явление правовой культуры характеризуется с точки зрения деятельностного, качественного, аксиологического, социологического, структурно-функционального подходов. Выделяются и характеризуются сопутствующие правовой культуре явления как правосознание и правовое поведение. В статье рассматриваются уровни правовой культуры личности и общества, их показатели и факторы. Отражается уровень овладения правовой культурой гражданами нашего государства, а также обоснована необходимость формирования высокого уровня правовой культуры населения и методы стимулирования ее повышения. Отражены функции правовой культуры в государстве.
Annotation. The article describes the content of the concepts "legal culture" and "legal state", highlights the features of the relationship between these concepts. The lack of consensus among researchers on the content and functions of legal culture is stated, and a number of its definitions are considered. The phenomenon of legal culture is characterized from the point of view of activity, qualitative, axiological, sociological, structural and functional approaches. The phenomena accompanying the legal culture are distinguished and characterized as legal consciousness and legal behavior.
lncRNA SNHG6 improves placental villous cell function
in an in vitro model of gestational diabetes mellitus
Authors: Meng Qian , Zhang Fang , Chen Haixia , Xu Wen , Chu Chu , Fu Fengqing , Xia Fei 
Published: March 2021

IntroductionThe purpose of this research was to investigate whether lncRNA SNHG6 has an effect on the pathogenesis of gestational diabetes mellitus (GDM).Material and methodsPlacental tissue was collected from patients with GDM and from pregnant women without GDM. Expression of lncRNA SNHG6 and EZH2 in the placental tissue was detected by qRT-PCR, immunohistochemistry (IHC), and western blotting. An in vitro cell model for GDM using high-dose glucose was employed to measure relative expression of mRNA and proteins by RT-qPCR and WB assay, and cell viability, apoptosis rate, invasion cell number, and wound healing rate by CCK-8, flow cytometry, transwell assay, and wound healing assay, respectively. Correlation between miRNA-26a-5p and EZH2 was investigated with a dual-luciferase reporter assay.ResultsCompared with the control placenta, lncRNA SNHG6 and EZH2 mRNA expression levels were significantly depressed and EZH2 protein expression was significantly downregulated in GDM placenta tissues (p < 0.001, respectively). In the in vitro cell model, lncRNA SNHG6 overexpression significantly improved high-dose glucose-induced HTR-8/SVneo cell function losses, including proliferation, migration, and invasion, by significantly depressing miRNA-26a-5p via regulation of EZH2 expression. The dual-luciferase reporter assay revealed that miRNA-26a-5p could target to EZH2 in HTR-8/SVneo cells.ConclusionsExpression of lncRNA SNHG6 in the placenta of patients with GDM is abnormally decreased. Overexpression of lncRNA SNHG6 improved HTR-8/SVneo cell function via regulation of the miRNA-26a-5p/EZH2-H3K27me3 pathway in an in vitro GDM model.
Anti-tumor effects of isoliquiritigenin in Bcl-2/Bax and PCNA expression of T24 human bladder cancer cells
Authors: Huang Zhanbin , Wu Qianmei , Wang Zhong 
Published: March 2021

IntroductionThe aim of this study was to investigate the proliferation and apoptosis of T24 after treatment with isoliquiritigenin (ISL) and to explore the underlying mechanism.Material and methodsT24 cells were divided into 6 groups and cultured. The five experimental groups were seeded into medium with 10, 20, 40, 80, and 160 µM ISL and the control group was administered with 0.01% DMSO. The cell morphology was observed using an optical microscope. The proliferation of cells and half maximal inhibitory concentration (IC50) were determined and calculated by MTS. Cell cycle and apoptosis were evaluated by flow cytometry. The migration ability of cells was detected by wound healing assay. The expression of B-cell lymphoma 2 (Bcl-2), Bcl-2-associated X protein (Bax), and proliferating cell nuclear antigen (PCNA) was determined by RT-qPCR and western blot.ResultsAt 24 h after treatment with ISL, morphology revealed that cell number diminished and the cell volume shrank with increasing concentration. According to the results of MTS, ISL significantly inhibited the T24 cell proliferation in a dose- and time-dependent manner. Flow cytometry showed that ISL could block the replication of T24 cell DNA from S phase to G2, therefore promoting cell apoptosis. Wound healing assay showed that at 48 h after treatment with ISL, the migration of T24 cells was remarkably inhibited. The results of RT-qPCR and Western blot revealed that after 24 h of treatment, the expression levels of Bcl-2 and PCNA were down-regulated, and the expression level of Bax was increased in the different dose of the ISL treated group.ConclusionsISL possesses detrimental effects on the viability of BC cell T24 in a dose-dependent manner via blocking the cell cycle and inducing apoptosis by down-regulation of PCNA and Bcl-2 expression and up-regulation of Bax expression.
Differential serum interferon-β levels in autoimmune thyroid diseases
Authors: Cheng Chao-Wen , Tang Kam-Tsun , Fang Wen-Fang , Lee Ting-I , Lin Jiunn-Diann 
Published: March 2021

IntroductionInterferon (IFN)-β is known as an environmental trigger for the occurrence of autoimmune thyroid disease (AITD). However, the association of another type-1 IFN, IFN-β, with AITD is unknown.Material and methodsIn the study, we explored the association of serum IFN-β levels with AITD in an ethnic Chinese (i.e., Taiwanese) population. We enrolled 160 patients with Graves’ disease (GD), 47 patients with Hashimoto’s thyroiditis (HT), and 119 healthy controls. Serum IFN-β and B-cell activating factor (BAFF) levels were quantified in healthy controls at the baseline and in patients with AITD either prior to receiving medication or while under medication. Thyroid function and thyroid-stimulating hormone receptor antibody (TSHRAb) levels were measured at the time of serum collection.ResultsSerum IFN-β levels were lower in the HT group than in the control group (p = 0.031). A significant inverse correlation was observed between IFN-β and TSHRAb levels in men with GD (r = –0.433, p = 0.044). Serum IFN-β levels were also negatively associated with BAFF levels in men with GD, HT, and AITD (r = –0.320, p = 0.032; r = –0.817, p = 0.047; and r = –0.354, p = 0.011, respectively), but not in women with GD, HT, or AITD.ConclusionsSerum IFN-β levels were lower in HT patients. Correlations of serum IFN-β with TSHRAb and BAFF levels were found to be gender-specific. Further well-designed studies with larger sample sizes are required to confirm our findings.
Predictive risk factors for worse outcomes in COVID-19 patients with different clinical features at baseline
Authors: Schiaroli Elisabetta , Gidari Anna , Brachelente Giovanni , Bastianelli Sabrina , Villa Alfredo , Ferri Carla , Francisci Daniela 
Published: March 2021

IntroductionCOVID-19 is characterized by a wide range of clinical expression and by possible progression to critical illness and death. Therefore it is essential to identify risk factors predicting progression towards serious and fatal diseases. The aim of our study was to identify laboratory predictive markers of clinical progression in patients with moderate/severe disease and in those with acute respiratory distress syndrome (ARDS).Material and methodsUsing electronic medical records for all demographic, clinical and laboratory data, a retrospective study on all consecutive patients with COVID-19 admitted to the Infectious Disease Clinic of Perugia was performed. The PaO2/FiO2 ratio (P/F) assessment cut‑off of 200 mm Hg was used at baseline to categorize the patients into two clinical groups. The progression towards invasive ventilation and/or death was used to identify critical outcome. Statistical analysis was performed. Multivariate logistic regression analysis was adopted to identify risk factors of critical illness and mortality.ResultsIn multivariate logistic regression analysis neutrophil/lymphocyte ratio (NLR) was the only significant predictive factor of progression to a critical outcome (p = 0.03) and of in-hospital mortality (p = 0.03). In ARDS patients no factors were associated with critical progression. Serum ferritin > 1006 ng/ml was the only predictive value of critical outcome in COVID-19 subjects with moderate/severe disease (p = 0.02).ConclusionsNeutrophil/lymphocyte ratio and serum ferritin are the only biomarkers that can help to stratify the risk of severity and mortality in patients with COVID-19.
TANGGAPAN TEOLOGIS TERHADAP PEMILIHAN KEPALA DAERAH DKI JAKARTA 2017-2022: SEBUAH REFLEKSI
Authors: Aritonang Arthur 
Published: March 2021

Artikel ini merefeksikan kembali peristiwa ketika Basuki Tjahaja Purnama (Ahok) maju kembali dalam kontestasi pada Pilkada DKI Jakarta beberapa tahun yang lalu. Persoalan Pilkada DKI Jakarta ini menjadi semakin sukar bermula ketika Pidato Ahok di Kepulauan Seribu pada 27 September 2016 diedit dan diunggah oleh Buni Yani ke media sosial. Pidato Ahok kemudian mengundang reaksi dari kalangan masyarakat Islam di Indonesia menuntut akan keadilan hukum di Indonesia. Ahok dianggap sebagai penista agama meskipun di kalangan Islam ada yang berpendapat berbeda bahwa ucapan Ahok tidak ada unsur menistakan agama Islam. Isu penistaan agama ini kemudian dipolitisasi oleh pihak lawan Ahok-Djarot baik melalui media sosial, ceramah yang dilakukan di masjid-masjid maupun dengan melakukan mobilisasi massa yang dengan tujuan yang sama yaitu membangun narasi politik untuk tidak memilih Ahok yang adalah orang ‘kafir’ (Kristen) dan juga keturunan etnis Tionghoa yang dianggap non-pribumi. Keberadaan Ahok ini merepresentasikan dari identitas pluralisme di Indonesia. Maka serangan politik identitas ini bertujuan untuk mengalahkan lawan politiknya tetapi secara langsung merupakan gerakan anti pluralisme. Melalui artikel ini penulis hendak menganalisis, memberikan tanggapan teologis dengan mengunakan pendekatan literatur kepustakaan maupun hasil wawancara. Temuan dari penelitian ini ialah, agar di masa mendatang jalannya pesta demokrasi dapat lebih beradab dan menempatkan agama pada porsi yang tepat yaitu membina karakter dan membangun spritualitas anak bangsa bukan malah sebaliknya masuk ke dalam ruang politik praktis yang nantinya dapat merusak martabat dari agama itu sendiri sekaligus menumpulkan kepekaan hati nurani anak bangsa dalam memilih calon pemimpin politik yang ingin mengabadikan dirinya bagi kepentingan orang banyak.
The digital competence of university students: a systematic literature review
Authors: Sánchez-Caballé Anna , Gisbert-Cervera Mercè , Esteve-Mon Francesc 
Published: March 2021

Digital competence is a pressing need for students in the 21st century. The present study is a systematic review of the literature on university students’ digital abilities. The methodology consisted of selecting documents (n=126) from three different databases (Scopus, Web of Science and ERIC) via peer review. The documents were selected for inclusion following predefined criteria and then analysed using a qualitative analysis software (ATLAS.ti). Digital competence is made up of several elements (information skills, content creation, communication, ethical skills, problem solving, technical skills/use and strategic skills). We identified that the most frequently-used terms in the literature are digital literacy and digital competence. However, the terminology used varies among authors. We also found that most authors do not believe that young people actually have the digital abilities that they are assumed to have. In other words, students do not have a high level of digital competence. Educational institutions therefore need to help them to develop this competence, which is so necessary in the context of 21st century education.
A COMPARISON OF THE PERFORMANCE OF CAGED LAYERS FED SORGIIUM GRAIN OR PEARL MILLET*
Authors: ODIBA J. Y. , SANFORD P. E. 
Published: March 2021

Two 280-day trials, each involving 468, 22-week-old caged commercial egg-strain pullets were conducted to Compare millet and sorghum grain as the main source of energy in laying diets. Diets containing 59.2 and 0, 41.0 and 24.0, 31.2 and 36.3 and 0 and 72.5% of sorghum grain and pearl millet, respectively, were studied in both trials The diets containing millet supported egg production, egg weight, feed conversion and egg shell thickness equivalent to those of the all-sorghum diet. Except in Trial 1, feed consumption of the pullets fed the millet-containing diets was not significantly lower than that of the pullets fed the all-sorghum diet. Haugh unit values tended to decrease as the level of millet was decreased. Feeding millet at a level as high as 72.5% Of the diet may have adverse effects on egg specific gravity and haugh units
GENETIC AND PHENOTYPIC ASSOCIATIONS OF JUVENILE BODY WEIGHTS AND EGG PRODUCTION TRAITS IN TWO STRAINS OF RHODE ISLAND CHICKENS
Authors: ONI O. O. , ABUBAKAR B. Y. , OGUNDIPE S. O. 
Published: March 2021

Data on body weight at 16 (WT16); 20 (WT20) weeks of age and at sexual maturity (WTSM) weight of first egg (WT1st), age at sexual maturity (ASM) and 120-d egg production (EN) were used to estimate genetic parameters in 636 hens of two strains of Rhode Island chikens. There were significant (P.01) differences between the two strains for all traits except for WTSM.The heritability estimates obtained ranged from 0.05 to 0.41 and 0.04 to 0.30 for strains 1 and 2 respectively. The genetic correlations obtained for the various traits were medium to high for the two strains. The phenotypic correlations were generally low but followed the same trend. The results indicate that selected stocks of the two strains would show improvements in egg production and age at sexual maturity if juvenile body weight (WT20) is employed as a selection criterion at housing for laying hens.
The Effect Of Season On The Yield And Nutritive Value Of Gliricidia Sepium And Leucaena Leucocephala
Authors: Odeyinka S. M. , Ademosun A. A. 
Published: March 2021

Four plots of Gliricidia and two plots of Leucuena were harvested at three monthly intervals to monitor dry matter yield, chemical composition and in vitro organic matter digestibility. The plants had been established (Gliricidia from stakes, Leucaena from seeds) and were spaced 1m apart on rows and 1m between rows. Each plot size was 6m x 6m.
There was no significant difference (P>0.05) in the dry matter yield of the two browse species. Season did not have significant (P>0.05) effect on the dry matter yield of Leucaena but had on that of Gliricidia (P<0.01). The early dry harvest produced the lowest yield for both Gliricidia and Leucaena and these were significantly lower than the yield from other harvests.
Season had significant effect (P<0.01) on the chemical composition of Leucaena except on the percent Acid Detergent Fibre (ADF) and lignin but season had no effect on the organic matter digestibilities of the two browse species: Leucaena was higher in nutritive value than Gliricidia.
PLANT PHYTATES AND OXALATES AND THEIR EFFECTS ON NUTRIENT UTILIZATION BY GOATS
Authors: ONWUKA C. F. I. 
Published: March 2021

The leaves of 37 browse species usually fed to ruminants in Nigeria were analysed for their phytic acid, pleytin - P and oxalic. The study indicated average phytic acid of phytic acid, i.e the mixed Ca and Mg salts contents ranged from 65.05 to 350.64 mg/g-1 in 18.32 - 100 mg g- and 0.10 -3.5 mg 100 mg. The Herbs leaves had the highest concentration Phytic acid while shrubs had the highest oxalate content. The in vivo trial with dwarf goats showed that, when maintained on browse and cassava peels, goats consumed 3.37 ±0.30 to 24.00 ±1.06 mg kg 1734 of phytic acid and 0.06 20.02 to 0.51 10.02 g d'W kg * 0.734 of oxalic acid. The CP, Ca and P intakes and excretion were also monitored. These two toxicants were correlated with protein; DM intake, DM digestibility and body weight Browse phytates and oxalates did not quite impair the performance of ruminant animals (Oke, 1996). Calcium animals significantly. Following digestion, nutrients sent into the soil Include Ca, P, N, C, being the main site of Zn etc.
Feedlot Performance and Carcass Characteristics of Steers Fed High-Energy Rations
Authors: Olayiwole M. B. , Ahmed M. B. , Bell T. D. 
Published: March 2021

THREE feeding trials, 24 [pure Zebu and Zebu x Friesian crossbred] steers per each, were conducted to compare 4 rations [treatments) at three different periods of the year.
Four equal and randomly distributed groups of steers were put on 4 different but iso-calorie rations. Levels of crude protein varied from 21.4 to 18.9% as shown in table 1. The steers were individually fed for 56 days to effect 1.12 kg. gain per head daily.
Digestibility levels of the four rations were determined [Table 2]. At slaughter, carcass data were obtained and analysed [Table 4]. Animal performance, and economics of the feeding operation data are presented in Table 3.
Results of these studies showed that the 30-20% cotton seed rations gave significantly [P <0.001] higher total liveweight gains, slightly heavier carcasses and better grades than the other two rations.
Considering results of all the parameters measured and Federal Government of Nigeria's concerted efforts to boost grains and meat production on large scales, ration 3 should be recommended. Because, with abundant supplies of grains and regular supplies of animals, faster throughput and increased gross return per feedlot per annum are feasible.
The Nature, Economics and Public Health Aspects of Bovine Brucellosis in Nigeria
Authors: Esuruoso G. O. 
Published: March 2021

BOVINE Brucellosis is a disease of cattle which causes abortions, retained placenta, inferillity and cconomic losses in calf pro duction in the affected herds. This disease has been diagnosed in various parts of the country (Efurioso, 1974). Although some herds were found to be free, others were moderately infected, while others still were heavily infected. Unfortunately, some of the heavily infected cattle herds were at the breeding centres from where animal were usually sold out to beginners about to start their own foundation herds. Therefore a trail of brucellosis could be followed to many of these herds.
From currently available information (Esuruoso & Hill, 1971; Esuruoso & Van Blake, 1972; Esuruoso 1974a & 1974b) it is estimated that direct losses due to bovine brucellosis alone in Oyo State is around ₦200,000 per 10,000 adult female cattle per annum. Losses in other parts of the country have been shown to be heavy in some places and low in others (Banerjee and Bhatty, 1970; Esurdoso, 1974b; Esaruoso, 1975; Nuru and Dennis, 1975) but can only be properly estimated when more work has been done to find out the status of most of the herds in relation to the incidence; only a very small percentage of herds in the northern state (Esurtoso, 1974b; Nuru and Dennis, 1975) have been investigated.
SCROTAL AND TESTICULAR DIMENSIONS IN SOME WEST AFRICAN BULLS
Authors: Osinowo O. , Dennis S. M. , Osori D. I. K. , Molokwu E. C. I. 
Published: March 2021

A series of studies were conducted to estimate testicular size from scrotal measurement and determine the relationship between testicular size, age and liveweight in some West African bulls. Repeatability estimate for scrotal circumference measurements between technicians was 0.96. scrotal circumference was highly correlated to paired testes weight (r = 0.88) and volume (r = 0.87). Testes weight and volume were reclosely related (r = 0.997) but their ration (g/cc)varied in 30 bulls from 0.962 to 1.119, with a mean and standard deviation of 1.027 + 0.029. The regression equation for estimating tests weight (Y) from scrotal circumference (X) was Y = 506.17 + 27.70X. Significant correlations existed between scrotal circumference and age (r from 0.59 to 0.79) or liveweight (r from 0.62 to 0.83) in N Dama, Bunaji and Sokoto-Gudali bulls. However, examination of the partial correlations showed that most of the age effects were attributable to changes in liveweight. Limited evidence indicate that young Bunaji bulls have larger testis than the other two breeds although they may be overtaken by Sokoto-Gudali bulls after 5 years of age