bluuebunny/crossref_metadata_2025_split huggingface dataset:
Renal Alterations Induced by Chronic Exposure to Therapeutic Doses of Antihypercholestremic Atorvastatin
Authors: Al-Doaiss Amin , Jarrar Yazun , Shati Ali , Alfaifi Mohammad , Al-Kahtani Mohammed , Jarrar Bashir 
Published: January 2021

Background:
Atorvastatin (ATOR) is widely used for the treatment and prevention of hypercholesterolemia and
various diseases, such as cardiovascular complication, with little data about the histopathological and ultrastructural renal
alterations that might be induced by this drug.

Objectives:
The present study was undertaken to investigate the potential toxicity of therapeutic doses of atorvastatin on the
microanatomy and ultrastructure of renal tissues from Wistar albino rats.

Methods:
Adult male Wistar albino rats received an oral daily dose of 5 mg/kg body weight for 90 consecutive days.
Biopsies from both kidneys of each study rat were taken for histopathological and ultrastructural examination.

Results:
ATOR-treated rats exhibited glomerular, tubular, and interstitial histological alterations, including degeneration,
necrosis, hyaline droplets, edema, cortical hemorrhages, mesangial hypercellularity, and blood capillary dilation and
congestion. In addition, ATOR exposure increased the activity of glucose-6-phosphate dehydrogenase and alkaline
phosphatase with a concurrent reduction in proteins and neutral mucosubstances content of the glomeruli and renal cells.
Moreover, ATOR-treated animals demonstrated glomerular ultrastructural alterations, consisting mainly of capillary tuft
dilatation, glomerular basement membrane thickening, and mesangial cell proliferation. The renal cells of the proximal
tubules demonstrated damaged mitochondria, degenerative cellular changes, endoplasmic reticulum dilatation, lysosomal
and autophagosome activation, nuclear alteration, myelin figure formation, and microvilli disorganization.

Conclusion:
The findings of the present work may indicate that ATOR can induce renal histological, histochemical, and
ultrastructural alterations that may affect kidney and other vital organ function.
THE EFFECT OF ACCOUNTABILITY AND TRANSPARENCY OF VILLAGE FUND MANAGEMENT
Authors: Ladewi Yuhanis , Supriadi Taufiq , Sjam Juska Meidy Enyke , * Welly , * Agista , Subowo Hery 
Published: January 2021

ABSTRACTÂ Purpose â€” The purpose of this study is to investigate and analyze the Effect of Accountability and transparency on the management of survey village funds in Merapi Selatan District and Pulau Pinang District, Lahat Regency. This research was conducted because there are phenomena associated with accountability and transparency in the management of village funds.Design/methodology/approach â€” The methodology used in this study consists of the type of this research is descriptive and associative research. The variables in this study are Accountability, Transparency, and Village Fund Management. The population in this study were 23 villages in Merapi Selatan and Pulau Pinang Districts, each village consisting of 3 respondents. Total questionnaires were distributed as many as 69 questionnaires, because there are some limitations of the questionnaire returned as many as 33 questionnaires and were processed.Findings â€” Based on the results of research conducted on all data obtained in 33 respondents in Merapi Selatan District and Pulau Pinang District, it was found that accountability significantly affected village fund management, while transparency did not significantly influence village fund management.Practical Implications â€” This research shows that accountability determines each activity and the final results of village government implementation activities must be accountable to the village community in accordance with statutory provisions.Â Originality/value â€” The test used in this research is the validity test, the reliability test, the classic assumption test, the hypothesis test, and the coefficient of determination test.Keywords â€” village fund management, accountability, transparency.Â
AN INVESTIGATION THE RELATIONSHIP BETWEEN ORGANIZATIONAL CULTURE AND EXTERNAL CUSTOMER SATISFACTION ORIENTATION (An Empirical Study of four stars hotels in Tripoli- Libya)
Authors: Zaroug Yousef Ali Mohamed , Thoyib Armanu , Hadiwidjojo Djumilah , Solaimun Ir 
Published: January 2021

Â ABSTRACTÂ Purpose â€” This research was conducted to study the effect of information sharing and information quality toward supply chain integration and farmer business performance.Design/methodology/approach â€” The type of this research is quantitative explanatory research. The data used in this study are primary data obtained by questionnaire. The sampling method uses multistage proportional random sampling, sample obtained amount 200 farmers. Data analysis in this study uses path analysis method with SPSS 23.Findings â€” The results of this research indicate that the quality of information is not significant to the integration of supply chain and farmer business performance. Information sharing has a positive and significant effect toward supply chain integration and farmer business performance, supply chain integration has a positive and significant effect toward farmer business performance.Practical Implications â€” Increasing global business competition and efforts to shorten product life cycles are the two main factors that encourage businesses to change their focus from competitive competition to mutually beneficial relationships and cooperation to improve business performance.Originality/value â€” The main objective of supply chain activities for business activities is a crucial element because with these activities the goods produced can reach the end consumers.Keywords â€” Information Sharing, Information Quality, Supply Chain Integration, Enterprise Performance.
INTRODUCING INDONESIAN CRITICAL VIEWS FOR SOCIO-ENVIRONMENTAL ACCOUNTING STUDIES: INSIGHT FROM TAN MALAKAâ€™S THOUGHT
Authors: Shahib Habib Muhammad , Sukoharsono Eko Ganis , Achsin M. , Prihatiningtias Yeney Widya 
Published: January 2021

PurposeÂ â€” This research tries to introduce one of the critical thoughts typical of Indonesia, namely Tan Malaka's view, which can be used in socio-environmental accounting studies.Design/methodology/approachÂ â€” This research uses a narrative literature review method, this article then compiles the Tan Malaka critical methodology pattern that focuses on the role of the government as a regulator, supervisor, and executor of socio-environmental issues to present an accountability framework for social-environmental issues to present an accountability framework for social-environmental issues.FindingsÂ â€” This result of this research shows that the development of paradigmatic studies in the field of accounting opens up great opportunities to complement, refine and even present concepts to new accounting models that are in line with the demands of the times, as in this article shown, which borrows Tan Malaka's thoughts. This thought has a role as a methodological basis for presenting the concept of social-environmental accountability typical of Indonesia, which is strongly influenced by the active political movements of the elements of society.Practical ImplicationsÂ â€” This research encourages the presence of socio-environmental accounting studies without forgetting the context of locality and the dynamic people's political aspirations.Originality/valueÂ â€” In particular, the framework of this research is composed of the aspiration of people affected by socio-environmental problems that do the political movement, together with NGOs, to protest the socio-environmental issues.Keywords Socio-Environmental, Accounting, Critical, Methodology, Tan MalakaPaper Type Research Paper.
A HOLISTIC CONCEPT OF NEUROINCOME AS A SOLUTION OF THE â€œTYRANY BOTTOM LINE â€œIN WORKPLACE
Authors: Leniwati Driana , Sukoharsono Eko Ganis , Prihatiningtias Yeney Widya , Purwanti Lilik 
Published: January 2021

PurposeÂ â€” This research aims to formulate a holistic concept of neuroincome.Design/methodology/approachÂ â€” The data collected are from various commercial bank employeesâ€™ experience with variation grade and position, local and international bank in Indonesia. Based on a spiritualist paradigm, the data are analysed by intuition using Taubat, Zikir, Doa, and Tafakur (TZDT) method within the framework of Neuro-Psycho Spiritual (NPS) methodology. The NPS methodology is used as an integrated science to study humans holistically by including materialistic, psycho, and spiritual dimensions. Â While the intuition in TZDT frame is a tool utilized to analyze data that relies entirely on God's guidance in the form of intuition and sense.FindingsÂ â€” The result of the study is a holistic concept of neuroincome in the form of â€œextraâ€ income and physical goods possible converted financially, earned by an individual as his/her working compensation stimulated by companyâ€™s tool/policy/system in workplace such as bonuses financially or bonus in the form of distribution of company shares, incentives, fringe benefits, performances allowances, job allowances, award, facilities and other related financial compensation. The positive stimuli happened if the nerves stimulate the release of hormone to perceive income in positive attitude such as empathy, helpful and sincerity. The negative stimuli happened if the nerves perceive the income excessively so it could make unethical actions or fraud. Then, qonaâ€™ah (sufficient sense) and modesty are found intuitively as a solution of â€œtyranny bottom lineâ€ in workplace. These attitudes stimulate a resurrection of the harmony of materialistic, psycho, and spiritual consciousness to live in a holistic way and bring closer to God in everyday working life.Practical ImplicationsÂ â€” The holistic concept of neuroincome is explained through Neuro-Psycho Spiritual (NPS) methodology.Originality/valueÂ â€” Authors are using various commercial bank employeesâ€™ experience with variation grade and position, local and international bank in Indonesia as their subject.Keywords Income, neuroscience, psychology, spirituality, spiritualist paradigm, consciousnessPaper Type Research PaperÂ
De Gentse Feesten. Nieuw licht op het ontstaan in 1843: een succesvol mercantiel initiatief
Authors: Devriese Luc , Brysse Adrien 
Published: January 2021

We weten allemaal dat het stadsbestuur een aardig woordje meespreekt in de organisatie van de jaarlijkse Gentse Feesten. En dat al heel lang, sinds het allereerste begin in 1843 namelijk. Het was dat bestuur dat toen inging op een petitie van handelaars om de feesten te organiseren. Het bepaalde wanneer de feesten zouden doorgaan: eerst in juni, later in juli en nog later meer bepaald in de week van de eenentwintigste, de Belgische nationale feestdag. En niet minder belangrijk: de stad subsidieerde vanaf het begin de diverse evenementen die het succes van de feesten zouden uitmaken.
Traditioneel wordt de stichting in 1843 in verband gebracht met een initiatief van de gemeentebestuurders, genomen op aandringen van de fabrikanten, om de vele wijkkermissen terug te brengen tot één enkel veel korter feest.
De Gentse Sint- Jacobskerk, parel van ons kunstpatrimonium
Authors: Beyaert Marc 
Published: January 2021

De Sint-Jacobskerk een van de erkende monumentale kerken van het Gentse, waarvan de geschiedenis bijna duizend jaar teruggaat: tot het jaar 1093. Dan werd immers de eerste, houten kapelkerk op de huidige locatie gebouwd. Het was meteen de oudste kerk gewijd aan de H. Jacobus in het hele gebied dat nu de Benelux vormt.
Zonderlinge en bijzondere Gentse straatnamen: Sint-Antoniuskaai en Kolveniersgang
Authors: Devriese Luc 
Published: January 2021

Een van de meest populaire heiligen in onze streken was Sint-Antonius. Dat was een belangrijke vroegchristelijke figuur (derde-vierde eeuw) die in kerkelijke teksten meestal onderscheiden wordt van een andere Sint-An tonius (‘van Padua’) door de toevoeging eremijt of abt. De Antonius ie ons hier bezig houdt, trok zich in een Egyptische woestijn terug en als werd als het ware de verpersoonlijking van de asceet, de heremiet of eremijt. Hij zou geleefd hebben van 251 tot 356, en dus 105 jaar geworden zijn. De heiligennaam kan dus tot verwarring leiden, vandaar ook de betiteling Antonius ‘de Grote’ of ‘van Egypte’ voor de sint in de titel hierboven.
Van de scholierenbeweging, via de landdagbeweging, naar een volksbeweging? Pol De Mont (1857-1931)
Authors: Wils Lode 
Published: January 2021

De veelzijdige literator Pol De Mont (1857 -1931) droeg gedurende decennia aanzienlijk bij tot de ontwikkeling van de Vlaamse taalbeweging in de richting van een nationale volksbeweging. Hij was een van de initiatiefnemers in de organisatie van een katholieke Vlaamse scholierenbeweging in de jaren 1870. Na zijn overgang naar het vrijzinnig liberalisme werd hij een voorvechter van de samenwerking van confessionele en vrijzinnige flaminganten, en van de democratische verruiming van hun beweging. Hij beleed heel sterk de völkische verbondenheid van Vlaanderen met Duitsland, sympathiseerde in de Eerste Wereldoorlog met het activisme, en werd een anti-Belgisch nationalist.__________
From the student movement via the ‘Landdag’ [Diet] movement towards a popular movement? Pol De Mont (1857-1931)
The protean belletrist Pol De Mont (1857-1931) was for many decades instrumental in the Flemish movement’s transition from a predominantly linguistic movement towards a mass national movement. De Mont played a leading role in the organisation of a Catholic Flemish student movement in the 1870s, and, following his conversion to secular liberalism, became an ardent proponent of an augmented collaboration between confessional and non-denominational flamingants, and of a democratic enlargement of the movement. Moreover, De Mont would profess the völkisch [folkish] union between Flanders and Germany, sympathise with the activist movement during the First Word War, and ultimately proclaim himself an anti-Belgian nationalist.
Daens: de making-of. Over de film Daens (1992) en de Daensmythe
Authors: Willems Gertjan 
Published: January 2021

Dit artikel onderzoekt hoe Louis Paul Boons historische roman Pieter Daens (1971) en, in het bijzonder, Stijn Coninx’ biopic Daens zich verhouden tot hun historisch onderwerp, de Aalsterse priester en politicus Adolf Daens (1839-1907). Het artikel toont hoe deze Daensvertellingen bijdragen tot de Daensmythe, die twee dimensies kent. Enerzijds een persoonlijke dimensie met de heroïsering van Daens, anderzijds een politiek-historische dimensie waarbij Daens en het daensisme gelijkgesteld worden met de bredere daensistische beweging en het ontstaan van de christendemocratie in Vlaanderen. De Daensmythe en de filmische popularisering ervan zorgden er mee voor dat Daens kon uitgroeien tot een historisch symbool dat zich flexibel laat inzetten in hedendaagse politiek-ideologische discoursen.__________
Daens: the making of. On the movie Daens (1992) and the ‘Daens myth’
This article analyses how Louis Paul Boon’s historical novel Pieter Daens (1971), and more particularly, Stijn Coninx’ biopic Daens correspond to their historical subject, the priest-politician Adolf Daens (1839-1907) from the town of Aalst. The article illustrates how these narrations have contributed to the Daens myth, which is comprised of two dimensions. On the one hand, it entails a personal dimension, deifying Daens. On the other hand, the myth contains a political-historical dimension, in which the figure of Daens and ‘daensism’ are equated with the broader ‘Daensic’ movement and even the origins of Christian democracy in Flanders. The ‘Daens myth’ and its popularization via film have contributed to the emergence of Daens as a historical symbol that can be used versatilely in contemporary political-ideological discourses.
Santiago apóstol combate a los moros en el Perú
Authors: Casasola Gómez Armando Iván 
Published: January 2021

Entre las manifestaciones culturales más relevantes y difundidas a lo largo de América Latina se encuentran las danzas, fiestas y representaciones de moros y cristianos; su origen hispánico es indudable y la mayoría de ellas están ligadas al culto hacia el apóstol Santiago, quien, como patrón de España y estandarte en la lucha contra los musulmanes durante la Reconquista, tiene una participación importante dentro de las representaciones; aunque también suelen representarse episodios de otras latitudes y en honor de diferentes santos católicos, su eje central siempre es la lucha entre el cristianismo y el Islam.
En nuestro país, se ha estudiado el tema en obras tan importantes como La danza de Moros y Cristianos (1972), de Arturo Warman; La historia de Fernando y Alamar. Contribución al estudio de las danzas de Moros y Cristianos en Puebla (México) (1984), de Gisela Beutler; y Moros y Cristianos. Una batalla cósmica (2001), de Alfonso Alfaro y Jorge Vértiz, por mencionar algunos.
Ambiguity Tolerance and Prospective Specialty Choice Among Third-Year Medical Students
Authors: Babenko Oksana , Linkiewich Delane , Lodewyk Kalee , Lee Ann 
Published: January 2021

Introduction: Poor tolerance of ambiguity is consequential in clinical practice, and has been linked to avoidance of family medicine, in which there is inherently more ambiguity. This study aimed to investigate the relationship between tolerance of ambiguity and prospective specialty choice of medical students in their third year of medical school. This stage of medical training is of particular importance as students develop clinical reasoning skills and encounter clinical ambiguity.
Methods: This was a cross-sectional study using an online survey. Sixty-one third-year medical students (62% response rate) from a large Canadian university completed the survey with a validated measure of ambiguity tolerance (the 29-item Tolerance of Ambiguity in Medical Students and Doctors scale) and their top three specialty choices. Specialty choices were subsequently grouped into two categories: family medicine (FM) and non-family medicine (non-FM) specialties.
Results: There was no significant mean difference in tolerance of ambiguity between students who reported interest in FM and students interested in non-FM specialties. Similarly, we observed no significant difference in tolerance of ambiguity between female and male students. Older students reported higher levels of ambiguity tolerance. Older students were also more likely to report FM as one of their top three specialty choices.
Conclusion: Qualitative studies are needed to explore possible reasons for the observed results, including the effects of digital information resources and clinical decision-making tools on medical students’ ambiguity tolerance. Medical educators should be aware that some students may require explicit training in how to respond to ambiguity.
RELAÇÃO ENTRE PROFESSOR E ALUNOS VÍTIMAS DE ABUSO: A INSERÇÃO NO CONTEXTO ESCOLAR
Authors: Miranda Dediane Alves Silva , Ferraz Rita de Cássia Souza Nascimento 
Published: January 2021

O presente estudo objetivou analisar a postura adotada pelo professor, em sala de aula, em relação ao aluno vítima de violência doméstica. A pesquisa foi realizada em duas escolas da rede municipal de Itapetinga-BA, focalizando 03 crianças do 4º ano do Ensino Fundamental I e suas respectivas professoras. Foram utilizados como instrumentos a observação e a entrevista semiestruturada. Os dados foram organizados nos seguintes eixos: a) a escola e sua relação com a criança vítima de Violência Doméstica; b) a atuação do professor em relação com a criança vítima de Violência Doméstica. Os dados sinalizaram a necessidade que os professores têm de refletirem e se posicionarem acerca das suas ações e posturas em relação a alunos, no cotidiano escolar, vítima de violência doméstica. Visualizamos as situações de interação entre as crianças apenas nos momentos de brincadeiras, troca de figurinhas e bate papos distantes dos conteúdos e atividades desenvolvidas. Por fim, concluímos que a postura do professor no enfretamento da violência contra criança e adolescente é de suma importância para garantir o mínimo de integridade para estes indivíduos que teve seus direitos violados.
STATE-RECOGNIZED MARRIAGE AND LIBERAL NEUTRALITY
Authors: Reitan Eric 
Published: January 2021

Abstract
While Ralph Wedgwood has recently argued that state recognition of marriage can be justified in a way consistent with the demands of political liberalism, Clare Chambers argues that such a policy violates the politically liberal state’s requirement of neutrality with respect to diverse reasonable conceptions of the good—and she thinks Wedgwood’s case to the contrary relies on a “lax” reading of the neutrality requirement, not the “strict” reading that preserves political liberalism’s distinctiveness. I argue that there is a way of reading Wedgwood that sees his defense of state-recognized marriage as attempting to meet the requirements of strict neutrality—a reading that sees state recognition of marriage as a “neutral facilitating policy,” that is, a policy that helps marriage-affirming reasonable doctrines overcome a disadvantage they would face (relative to other reasonable doctrines) absent policy intervention by the state. I conclude, however, that a state policy that refuses to recognize polyamorous marriages may not qualify as a neutral facilitating policy, and hence that Wedgwood’s argument may fail to support the policy regime he favors but might support a more permissive marital policy.
DO DIVISION PUZZLES PROVIDE A REASON TO DOUBT THAT YOUR ORGANISM WAS EVER A ZYGOTE?
Authors: Hershenov David , Hershenov Rose 
Published: January 2021

AbstractA number of philosophers maintain that the destruction of an embryo in the first 2 weeks after fertilization is not morally problematic as it is metaphysically impossible for any human organism to then have existed. We contend that the typical adult human organism was once a zygote so there is no metaphysical shortcut to justify early abortion. We show that five arguments against human organisms ever having been zygotes fail. All of the arguments have to do with one variant or another of the zygote or early embryo dividing. They do not provide any reason to believe that since some adult organisms are not identical to zygotes due to earlier divisions, none could have been.
Central Nervous System Infections
Authors: Caulfield Anna Finley , Blackburn Brian G. 
Published: January 2021

Central nervous system (CNS) infections are associated with a high morbidity and mortality. Fortunately, the incidence of acute community-acquired bacterial meningitis has declined with the advancement and implementation of vaccination programs over the past 30 years. Treatment with corticosteroids, along with initial antimicrobial therapy, has also decreased the morbidity and mortality of patients with acute Streptococcus pneumoniae meningitis in developed countries. Molecular diagnostic testing may become a helpful tool to identify bacterial pathogens for targeted treatments. This review covers common CNS infections with a focus on the diagnosis and initial management of the adult patient suspected of having acute meningitis and encephalitis.
Key words: acute meningitis, brain abscess, chronic meningitis, encephalitis, ventriculitis