bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Channel Estimation-and-Artificial Noise Cancellation Imperfection on Artificial Noise-Aided Energy Harvesting Overlay Networks
Authors: Ho-Van Khuong , Do-Dac Thiem 
Published: February 2021

Abstract
EHONs (Energy Harvesting Overlay Networks) satisfy stringent design requirements such as high energy-and-spectrum utilization efficiencies. However, due to open access nature of these networks, eavesdroppers can emulate cognitive radios to wire-tap legitimate information, inducing information security to become a great concern. In order to protect legitimate information against eavesdroppers, this paper generates artificial noise transmitted simultaneously with legitimate information to interfere eavesdroppers. Nonetheless, artificial noise cannot be perfectly suppressed at legitimate receivers as for its primary purpose of interfering only eavesdroppers. Moreover, channel information used for signal detection is hardly estimated at receivers with absolute accuracy. As such, to quickly evaluate impact of channel estimation-and-artificial noise cancellation imperfection on secrecy performance of secondary/primary communication in ANaEHONs (Artificial Noise-aided EHONs), this paper firstly proposes precise closed-form formulas of primary/secondary SOP (Secrecy Outage Probability). Then, computer simulations are provided to corroborate these formulas. Finally, various results are illustrated to shed insights into secrecy performance of ANaEHON with key system parameters from which optimum parameters are recognized. Notably, secondary/primary communication can be secured at different levels by flexibly adjusting various parameters of the proposed system model
An Environmentally Friendly Phosphorus-Modified Cellulose/Silica Hybrid Hydrogel for Fire Prevention and Firefighting
Authors: Nabipour Hafezeh , Shi Hu , Wang Xin , Hu Xiangming , Song Lei , Hu Yuan 
Published: February 2021

Abstract
Wildfires have been recognized as a natural incident in some forests, however, fire season is now more severe and extensive, even in tropical rainforests in which fire could have damaging impacts. A hydrogel is a 3-D polymeric structure encompassing cross-linked and hydrophilic macromolecules. In comparison with water, hydrogels have shown some superiorities in terms of water-binding, cooling, and sealing, which make them be applied in forest fire prevention programs for improving fire-extinguishing performance. In this study, an environmentally friendly phosphorus-modified cellulose/silica hybrid hydrogel was prepared based on the modified methylcellulose by 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide–itaconic acid (DOPO-ITA) and silica nanoparticles. The storage (G') and loss (G") moduli increased with the increment of silica nanoparticles content, owing to the role of silica nanoparticles as crosslinking agent. In the fire prevention experiments, the grass treated with the methylcellulose@DOPO-ITA@silica hybrid hydrogel shows self-extinguishing behavior, whereas those treated with ordinary water or methylcellulose hydrogel can be easily ignited after one week. In the firefighting experiments, the methylcellulose@DOPO-ITA@silica hybrid hydrogel displays much shorter extinguishing time and lower consumption volume than ordinary water and the methylcellulose@DOPO-ITA hydrogel. This work presents an environmentally-friendly, non-toxic, and biodegradable cellulose-based hybrid hydrogel for fire prevention and firefighting of wildfires.
Abnormal CD8 T cells induce and track Alzheimer’s-like neurodegeneration
Authors: Wheeler Christopher , Panwar Akanksha , Rentsendorj Altan , Jhun Michelle , Cohen Robert , Cordner Ryan , Gull Nicole , Pechnick Robert , Duvall Gretchen , Mardiros Armen , Golchian David , Schubloom Hannah , Jin Lee-way , Dam Debby Van , Vermeiren Yannick , De Reu Hans , De Deyn Peter Paul , Black Keith 
Published: February 2021

Abstract
Sporadic Alzheimer’s disease, the most common neurodegenerative disorder of aging, is characterized by cerebral plaques and neurofibrillary tangles. Experimental rodents develop plaques but neither tangles nor substantial neurodegeneration under conditions that guarantee Alzheimer’s in humans, suggesting rodents lack critical co-initiation factors. Accumulation of antigen-reactive memory CD8 T cells increases with aging, and was recently revealed as a hallmark of human Alzheimer’s. The impact of this process on disease initiation, however, has not been established because age-related T cell changes are muted in rodents. We developed a mouse model of human-like CD8 T cell aging that promotes antigen-reactive memory CD8 T cell accumulation. Here we show that these “hiT” mice develop all major hallmarks of Alzheimer’s with aging, including tangle-like inclusions and substantial neurodegeneration. Antigen-reactive CD8 T cells analogous to those in hiT mice increased in Alzheimer’s brain, but decreased earlier in blood, where their loss effectively distinguished the Alzheimer’s continuum from aging controls. Our findings establish a clinically relevant mouse model for sporadic Alzheimer’s and show that age-related immune dysfunction critically contributes to its initiation. They also identify useful immune-based targets to track and potentially treat human Alzheimer’s, while validating a model system to examine age-related disease immuno-biology more generally.
Earthquake Vulnerability in the Himalaya by Integrated Multi-Criteria Decision Models
Authors: Malakar Sukanta , Rai Abhishek K 
Published: February 2021

Abstract
Himalaya is one of the most seismo-tectonically active mountain on the surface of the earth. Recurring moderate and high magnitude earthquakes are not uncommon in this region. This paper maps the earthquake vulnerability in the Himalayan seismo-tectonic zone using integrated multi-criteria decision models. Several factors influence the earthquake vulnerability in a region, such as the social, geotechnical, structural, and physical parameters. We have used the analytical hierarchy process (AHP) approach to determine the weights of various parameters, which have been further used in the VIseKriterijumska Optimizacija I Kompromisno Resenje (VIKOR) and Grey Relational Analysis (GRA) method to develop earthquake vulnerability maps for the study area. The map generated by AHP-VIKOR reveals that 12.93% of the Himalayan region is highly vulnerable, 26.39% moderately vulnerable, and 60.67% of the area is relatively low vulnerable. On the other hand, the AHP-GRA method reveals that 9.75% of the region is high vulnerability zone, 20.26% moderate, 70% as a relatively low vulnerable zone. A high correlation between the final vulnerability maps generated from AHP-VIKOR and AHP-GRA further validates our result. The results of this paper may be useful for the various hazard mitigation and infrastructure planning agencies in the Himalayan seismicity zone.
The impact of the COVID-19 response on the provision of other public health services in the U.S.: A cross sectional study
Authors: Kintziger Kristina W. , Stone Kahler W. , Jagger Meredith , Horney Jennifer A. 
Published: February 2021

Abstract
Background

Funding and staff formerly dedicated to routine public health tasks (e.g., responding to communicable and non-communicable diseases, investigating foodborne outbreaks, conducting routine surveillance) and services (e.g., environmental health, substance abuse, maternal-child health) may no longer be available in many public health departments due to the COVID-19 response. The objective of this study was to assess the extent to which staffing for essential public health services has been redirected to the COVID-19 response.
Methods

This is a cross-sectional study using a survey distributed through the Qualtrics platform. Individuals (N = 298) working in public health across governmental and academic public health departments in the U.S. during the ongoing COVID-19 pandemic response were surveyed. Survey items measured multiple domains including professional experience (i.e., training, years of experience, content expertise, job functions), mental and physical health status (i.e., generalized anxiety, depression, burnout), and career plans (i.e., pre-pandemic vs. current career plans).
Results

The total number of content expertise areas and programmatic functions covered by individual public health workers increased between January and September of 2020, with 26% (73 of 282) of respondents reporting an increase in both. The total number of respondents working in infectious disease and preparedness remained constant, while declines were reported in program evaluation (-36%) and health education (-27%) and increases were reported in disease investigation (+ 35%).
Conclusions

The provision of many essential public health functions and tasks have been limited or eliminated while the U.S. public health workforce responds to the COVID-19 pandemic. These findings highlight opportunities for funding and professional development of public health systems, both during and after the COVID-19 response, to help ensure the continuity of essential public health services, staffing sustainability, and preparedness for future public health emergencies in the U.S.
Trial registration:
Not applicable.
Simple Mobile technology health management tool for people with severe mental illness: a randomised controlled feasibility trial
Authors: Röhricht Frank , Padmanabhan Raguraman , Binfield Paul , Mavji Deepa , Barlow Sally 
Published: February 2021

Abstract
Background:
Severe mental illness (SMI) is associated with care delivery problems due to the patient’s psychosocial impairment and corresponding functional disability. Current routine appointment systems do not adequately foster recovery care and are not systematically capturing information suggestive of urgent care needs.
This study aimed to assess the
feasibility, acceptability, and potential clinical benefits of a
mobile technology health management tool to enhance community care
in people with severe mental illness.
Methods:
This randomised-controlled feasibility pilot study utilised mixed quantitative (measure on subjective quality of life as primary outcome; questionnaires on self-management skills, medication adherence scale as secondary outcomes) and qualitative (thematic analysis) methodologies. The intervention was a simple interactive technology (Short Message Service (SMS) communication system called ‘Florence’, and had three components: medication and appointment reminders, daily individually defined wellbeing scores and optionally coded request for additional support. Eligible participants (diagnosed with schizophrenia, schizoaffective disorder or bipolar disorder ≥ 1 year) were randomised (1:1) to either treatment as usual (TAU) or TAU and the technology-assisted intervention.
Results:
The health technology tool appeared to offer a practicable and acceptable intervention for patients with SMI in managing their condition. Recruitment and retention data indicated feasibility, the qualitative analysis identified suggestions for further improvement of the intervention. Preliminary results suggest that service users engaged well and benefited from SMS reminders and from monitoring their individual wellbeing scores. The care coordinators did not utilise the intervention per protocol due to a variety of organisational barriers. Quantitative analysis of outcomes (including a patient-reported outcome measure (PROM) on subjective quality of life, self-efficacy/competence and medication adherence) did not reveal significant differences between groups over time, given high baseline scores. The wellbeing scores, however, were positively correlated with all outcome measures.
Conclusion:
It is feasible to conduct an adequately powered full trial to evaluate this intervention. Inclusion criteria should be revised to include service users with a higher level of need and clinicians should receive more in-depth assistance in managing the tools effectively. The preliminary data suggests that this intervention can aid recovery care and individually defined wellbeing scores are highly predictive of a range of recovery outcomes; they could, therefore, guide the allocation of routine care resources.
Trial registration
ISRCTN 34124141; retrospectively registered, date of registration 05/11/2019.
Microwave assisted ultrafast immobilization of CuO nanostructures in paper matrices for antimicrobial applications
Authors: Aggrawal Sudiksha , Pradhan Debabrata , Mohanty Paritosh 
Published: February 2021

Abstract
CuO nanoflakes with dimension of 50-150 nm × 200 nm were successfully immobilized on the surface of cellulose fibers by an ultrafast (5 min reaction time), scalable microwave assisted method. The achievement of high retention of CuO upto 70% has been phenomenal as the immobilization was carried out in the absence of any linker, binder or retention aid. The successful recyclability of the CuO immobilized paper matrices upto five consecutive cycles while retaining 87% of immobilized CuO nanostructures in paper matrices has been unprecedented. The antimicrobial activities of the paper matrices have been investigated by deactivating both G. trabeum and E. coli . The CuO immobilized paper matrices have desisted the growth of G. trabeum for upto 28 days, which is phenomenal and completely deactivated E. coli of the CFU in order of 10 7 in the presence of visible light with exposure time of 2 h only.
In silico exploration of phytoconstituents from Phyllanthus emblica and Aegle marmelos as potential therapeutics against SARS-CoV-2 RdRp
Authors: Pandey Khushboo , Lokhande Kiran Bharat , Swamy K. venkateswara , Nagar Shuchi , Dake Manjusha 
Published: February 2021

Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide has increased the importance of computational tools to design a drug or vaccine in reduced time with minimum risk. Earlier studies have emphasized the important role of RNA-dependent RNA polymerase (RdRp) in SARS-CoV-2 replication as a potential drug target. In our study, comprehensive computational approaches were applied to identify potential compounds targeting RdRp of SARS-CoV-2. To study the binding affinity and stability of the phytocompounds from Phyllanthus emblica and Aegel marmelos within the defined binding site of SARS-CoV-2 RdRp, they were subjected to molecular docking, 100ns molecular dynamics (MD) simulation followed by post-simulation analysis. Further, to assess the importance of features involved in the strong binding affinity, molecular field-based similarity analysis was performed. Based on comparative molecular docking and simulation studies of the selected phytocompounds with SARS-CoV-2 RdRp revealed that, EBDGp possess stronger binding affinity (-23.32 kcal/mol) and stability than other phytocompounds and reference compound, Remdesivir (-19.36 kcal/mol). Molecular field-based similarity profiling has supported our study in the validation of the importance of the presence of hydroxyl groups in EBDGp, involved in increasing its binding affinity towards SARS-CoV-2 RdRp. Molecular docking and dynamic simulation results confirmed that EBDGp has better inhibitory potential than Remdesivir and can be an effective novel drug for SARS-CoV-2 RdRp. Furthermore, binding free energy calculations confirmed the higher stability of the SARS-CoV-2 RdRp-EBDGp complex. These results suggest that the EBDGp compound may emerge as a promising drug against SARS-CoV-2 and hence requires further experimental validation.
Increase energy use efficiency and economic benefit with reduced environmental footprint in rice production of central China
Authors: Yuan Shen , Zhan Xuewu , Xu Le , Ling Xiaoxia , Peng Shaobing 
Published: February 2021

Abstract
Identifying an energy-efficient system with low energy use, low global warming potential (GWP), and high profitability is essential for ensuring the sustainability of the agro-environment. Given the global importance of China’s rice production, this study determines energy, environmental, and economic performances of transplanted (TPR) and direct-seeded rice system (DSR) in central China. The results showed that total energy inputs for TPR and DSR were 31.5 and 22.8 GJ ha− 1 across two growing seasons, respectively. Higher energy input for TPR primarily resulted from extra energy use of the nursery beds and transplanting. Higher energy output of DSR (202.5 GJ ha− 1) over that of TPR (187.7 GJ ha− 1) was due to a slightly higher yield from DSR. Therefore, DSR exhibited significantly higher energy use efficiency than that of TPR. Lower specific energy for DSR (2.78 MJ kg− 1) relative to TPR (4.02 MJ kg− 1) indicated that the energy used to produce per unit of rice grain could be reduced by 30.8% by adopting DSR. On average, GWP of DSR was reduced by 5.6% compared with TPR. Moreover, DSR had a 55.8% higher gross return and a 25.7% lower production cost than those of TPR. Overall, compared with TPR, DSR has the potential to increase gross economic return and energy output with reduced energy input and emissions. Therefore, this study suggests that DSR is an environmentally-sound and economically-viable production system. As such, DSR is noted as an energy-efficient and climate-smart production system that could be used by policymakers and farmers to achieve not only improvements in the environment but also financial benefits.
Extracting and physicochemical properties of carotenoprotein from shrimp processing waste by proteases-mediated hydrolysis
Authors: Pourashouri Parastoo , Mirsadeghi Hojat , Khodanazary Aynaz 
Published: February 2021

Abstract
In this study, carotenoprotein from Pacific white shrimp (Litopenaeus vannamei) processing waste was extracted with the aid of alcalase (CP-A) and pepsin (CP-P) at various levels (0-4 units/100g waste) for different times (0–240 min). Recovery of carotenoids and protein increased with increasing enzymes levels (3 unit/g) and hydrolysis times until 180 min (p<0.05). The extracted carotenoprotein by pepsin and alcalase consisted of 72.11-75.32% protein contents and carotenoids were in the range of 330-530 µg/g samples. The phenylalanine, lysine, methionine and valine as essential amino acids were high at CP-A and CP-P. The dominant non-essential amino acids in carotenoproteins were aspartic acid, glutamic acid, glycine and alanine. It was rich in mono and polyunsaturated fatty acids. The CP-A showed higher DHA and EPA (8.52 and 6.49%) than CP-P (5.55 and 5.49%). The saturated fatty acids were reduced after enzymatic hydrolysis and contents were higher in carotenoproteins. The extracted samples showed a significant amount of mineral contents. Sodium, phosphorus, magnesium and potassium contents were found to be higher in CP-A. The lead and copper reduced as a result of hydrolysis. Therefore, carotenoprotein from processing residue of pacific white shrimp could be used as the value-added nutritious enriching food or feed powder.
The Surface Wind Influence on the Heat Fluxes Variability on the South Atlantic
Authors: Lindemann Douglas , Avila-Diaz Alvaro , Pezzi Luciano , Rodrigues Jackson , Freitas Rose Ane , Coelho Lucas , Alonso Marcelo , Cerón Wilmar L. 
Published: February 2021

Abstract
An adequate representation by models and reanalyzes is fundamental since the coverage by observational data on the oceans is still limited. Therefore, this paper aims to evaluate the influence of the wind near the surface on the heat fluxes during the southern winter and summer seasons. Datasets from Coupled Model Intercomparison Project Phase 5 (CMIP5) and reanalyzes were used, in comparison to Objectively Analyzed Air - sea Fluxes (OAFlux) for the South Atlantic Ocean (SAO) during 1980-2005. Results point out an overestimation on the CMIP5 models and reanalyzes to reproduce the heat flux latent and sensible fluxes of SAO, mainly at medium and high latitudes. One possibility may be related the underestimating of surface wind speed, causing an impacts on the heat exchange between ocean and atmosphere. It was also possible to verify that the representation of heat flux, specific humidity, and air and ocean temperatures shows small biases (Mean Bias Error (MBE) to specific humidity (±5 kg.kg-1) and sensible heat flux (±10 W.m-2)). To the test Root Mean Square Error (RMSE)-observations Standard deviation Ratio (RSR), air temperature values are less than 1 °C, and for the wind with values greater than 2 m.s-1. There is less precision of CMIP5 models than OAFlux, resulting in low correlation values (between -0.3 and 0.3). On the other hand, the reanalyzes show small biases in air and ocean temperatures (between ±1 °C) and significant correlations (above 0.9) with the best performances for the NCEP and ERA5.
Synthesis of Nano-Crystalline Zr0.8Sn0.2TiO4 Powder by Choline-Chloride-Malonate Deep Eutectic Solvents
Authors: Wang Qi-feng , Gu Yong-jun , Li Qian , Huang Jin-liang , Chen Min , Gao Shun , Kim Bok-hee 
Published: February 2021

Abstract
Chloride-malonate deep eutectic solvent (Cm-DES) was applied to synthesize nano-crystalline Zr0.8Sn0.2TiO4 ceramic powder by using Zr(CH3COO)4, SnCl2∙2H2O and Ti(OCH3CH3)4 as raw materials. The nano-crystalline Zr0.8Sn0.2TiO4 powder was obtained at 450 °C, dramatically lower than that by solid state reaction. Meantime, the grain size of as-synthesized Zr0.8Sn0.2TiO4 powder at 450 °C is 10.7 nm. In the synthesized process, Cm-DES, as a solvent and template, affects the synthesis process and the time required for synthesis is greatly reduced. These results show that the Cm-DES is suitable and prospective for the synthesis of nano-crystalline Zr0.8Sn0.2TiO4 ceramic powder, which could contribute to reduce energy consumption and time cost.
The Role of Trust and Hope in Antipsychotic Medication Reviews in Primary Care Settings: A Realist Review.&nbsp;
Authors: Grünwald Lisa Marie , Duddy Claire , Byng Richard , Crellin Nadia , Moncrieff Joanna 
Published: February 2021

Abstract
Background: Increasing number of service users diagnosed with schizophrenia and psychosis are being discharged from specialist secondary care services to primary care, many of whom are prescribed long-term antipsychotics. It is unclear if General Practitioners have the confidence and experience to appropriately review and adjust doses of antipsychotic medication without secondary care support.Aim: To explore barriers and facilitators of conducting antipsychotic medication reviews in primary care for individuals with no specialist mental health inputDesign & Setting: Realist review in general practice settings. Method: A realist review has been conducted to synthesise evidence on antipsychotic medication reviews conducted in primary care with service users diagnosed with schizophrenia and/or psychosis. Following initial scoping searches and discussions with stakeholders, a systematic search and iterative secondary searches were conducted. Articles were systematically screened and analysed to develop a realist programme theory explaining the contexts (C) and mechanisms (M) which facilitate or prevent antipsychotic medication reviews (O) in primary care settings, and the potential outcomes of medication reviews.Results: Antipsychotic medication reviews may not occur for individuals with only primary care medical input. Several, often mutually reinforcing, mechanisms have been identified as potential barriers to carrying out meaningful reviews, including low expectations of recovery for people with severe mental illness, a perceived lack of capability to understand and participate in medication reviews, linked with a lack of information shared in appointments between GPs and Service Users, and perceived risk and uncertainty regarding antipsychotic medication and illness trajectory. Conclusions: The review identified reciprocal and reinforcing stereotypes affecting both GPs and service users. Possible mechanisms to counteract these barriers are discussed, including realistic expectations of medication, and the need for increased information sharing and trust between GPs and service users.