bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nurse-led Intervention Improves Survival Following Severe Hypoglycaemia in Type 2 Diabetes Irrespective of Baseline Risk Characteristics.
Authors: Pearson Sam Matthew , Kietsiriroje Noppadol , Whittam Beverley , Birch Rebecca J. , Campbell Matthew D , Ajjan Ramzi A 
Published: July 2021

Abstract
BackgroundRecent evidence suggests severe hypoglycaemia may pose a risk of premature mortality to individuals with type 2 diabetes. Evidence surrounding strategies to mitigate this risk is currently lacking as is evidence regarding risk stratification of such patients. MethodsWe performed a post-hoc analysis from a previously published RCT studying the impact of a structured nurse led intervention following severe hypoglycaemia. A Cox regression model was used to identify baseline characteristics associated with increased mortality and to adjust for differences between study groups. Kaplan Meier (KM) curves were created to demonstrate differences in outcome between study groups across a number of variables.Results124 participants (mean age 75, 57% male) were included in analysis. Diabetes severity score, age and insulin use were found to correlate with mortality, while other variables including HbA1c and presence of established cardiovascular disease showed no correlations. When comparing KM curves between study groups, the intervention appeared to be beneficial irrespective of glycaemic control, presence of vascular disease, diabetes severity score or age.ConclusionIn this analysis, only diabetes severity score, age and insulin use were significantly associated with death following severe hypoglycaemia in the community. A structured nurse-led intervention appears to reduce the risk of death irrespective of age, co-morbidities or type of treatment. Trial registrationData is taken from a previously published randomised controlled trial with trial registration NCT04422145.
Hyperspectral Imaging and Convolutional Learning for Sugariness Prediction: Example of Syzygium Samarangense
Authors: Chen Chih-Jung , Yan Yung-Jhe , Huang Chi-Cho , Chien Jen-Tzung , Chu Chang-Ting , Jang Je-Wei , Chen Tzung-Cheng , Lin Shiou-Gwo , Shih Ruei-Siang , Ou-Yang Mang 
Published: July 2021

Abstract
Sugariness is one of the most important indicators to measure the quality of Syzygium samarangense, which is also known as the wax apple. In general, farmers used to measure sugariness by testing the extracted juice of the wax apple products. Such a destructive way to measure sugariness is not only labor-consuming but also a wasting of products. Therefore, non-destructive and quick techniques for measuring sugariness would be significant for wax apple supply chains. Traditionally, the non-destructive method to predict the sugariness or the other indicators of the fruits was based on the reflectance spectra or Hyperspectral Images (HSIs) using linear regression such as Multi-Linear Regression (MLR), Principal Component Regression (PCR), and Partial Least Square Regression (PLSR), etc. However, these regression methods are usually too simple to precisely estimate the complicated mapping between the reflectance spectra or HSIs and the sugariness. This study presents the deep learning methods for sugariness prediction using the reflectance spectra or HSIs from the bottom of the wax apple. A non-destructive imaging system fabricated with two spectrum sensors and light sources is implemented to acquire the visible and infrared lights with a range of wavelengths. In particular, a specialized Convolutional Neural Network (CNN) with hyperspectral imaging is proposed by investigating the effect of different wavelength bands for sugariness prediction. In the experiments, the ground-truth value of sugariness is obtained from a commercial refractometer. The experimental results show that using the whole band range between 400 nm and 1700 nm achieves the best performance in terms of Brix error. CNN models attain the Brix error of ±0.552, smaller than ±0.597 using Feedforward Neural Network (FNN). Significantly, the CNN’s test results show that the minor error in Brix interval 0-10°Brix and 10-11°Brix are ±0.551 and ±0.408, these results indicate that the model would have the capability to predict if sugariness is below 10°Brix or not, which would be similar to the human tongue. These results are much better than ±1.441 and ±1.379 by using PCR and PLSR, respectively. Moreover, this study provides the test error in each Brix interval within one °Brix, and the results show that the test error is varied considerably within different Brix intervals, especially on PCR and PLSR. On the other hand, FNN and CNN obtain robust results in terms of test error.
Natural Killer/T-Cell Lymphoma in Children and Adolescents: Clinicopathologic and Gene Expression Profiling Study of 22 Cases
Authors: Guannan Wang , Wugan Zhao , Xudong Zhang , Dandan Zhang , Chongli Zhang , Wencai Li 
Published: July 2021

Abstract
Background: There have been few studies on large-scale samples regarding natural killer/T-cell lymphoma (NKTCL) in children and adolescents for the low incidence of NKTCL in this age group. The clinical, histopathological and molecular features of 22 young people with NKTCL were evaluated. The aim of the present study was to provide a better understanding of the clinicopathological aspects of this rare entity of lymphoma.Results: There were 15 male and 7 female patients (male/female, 2.14:1) with a median age of 15 years. The results revealed that the nasal site was the most involved region while non-nasal sites were observed in 27.3% out of all cases, and exhibited histopathological and immunohistochemical features similar to the cases in adults. Seven (36.8%) out of all the 19 patients during the follow-up died of the disease, and the median follow‑up period was 44 months. Moreover, patients treated with radiotherapy/chemotherapy showed significantly inferior OS compared with the untreated patients. High mutation frequencies were detected including KMT2C (5/5), MST1 (5/5), HLA-A (3/5) and BCL11A (3/5), which involved in modifications, tumor suppression and immune surveillance. Conclusion: NKTCL in children and adolescents is a rare type of T/NK cell neoplasms. This disease is difficult to distinguish from other EBV-related disorders in young people. Furthermore, active treatment is necessary after the diagnosis of NKTCL is confirmed.
The curl of angular velocity and its mechanical significance
Authors: GuangYi PU , Cheng-Xi Pu 
Published: July 2021

Abstract
The curl of the vector field is widely used in modern field theory, fluid mechanics, mathematics, electromagnetic field, and other fields. In this paper, by introducing an auxiliary vector parameter (We called 𝑷𝑼⃗⃗⃗⃗⃗⃗ ) whose direction satisfies the right-hand thread rule the mathematical expression of angular velocity vector curl (𝛁×𝝎⃗⃗⃗ ) was obtained by analogy with the method of defining velocity vector curl (𝛁×𝒗⃗⃗ ). We also pointed out that the laminar flow of viscous fluid in a circular pipe (Hogen-Poiseuille flow) in nature is a typical real example of angular velocity vector curl (𝛁×𝝎⃗⃗⃗ ). Moreover, a concise mathematical equation (Equation(11)) was given, which could be used to describe some motion characteristics of vortex ring theoretically; Therefore, the motion of a single vortex ring has the dual characteristics of the velocity curl(𝛁×𝒗⃗⃗ ) and the angular velocity curl(𝛁×𝝎⃗⃗⃗ ) at the same time.
Rufausnutzung zwischen Lauterkeitsrecht und Markenschutz: Umwege und Auswege
Authors: Heizmann Reto , Loacker Leander D. 
Published: July 2021

Im Wettbewerb zwischen Unternehmen kommt es immer wieder vor, dass sich Produzenten insbesondere bei der Produktbezeichnung an bereits etablierte Bezeichnungen von Fabrikaten ihrer Mitbewerber anlehnen, um Assoziationsvorteile zu generieren. Entsprechende Sachverhalte werfen Fragen sowohl des Lauterkeits- wie auch des Immaterialgüterrechts auf. Ihre sachgerechte Beantwortung sollte sich nicht nur auf technische Fragen des Vor- bzw. Nachrangs der jeweils angerufenen Abwehrnormen beschränken, sondern muss der Grundsatzkonzeption der beiden Rechtsgebiete und ihrem Zusammenspielgebührend Rechnung tragen. Ein aktueller Entscheid des Handelsgerichts Bern gibt Anlass dazu.
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Dans le cadre de la concurrence entre entreprises, il n’est pas rare que des producteurs adoptent des désignations de produits déjà établies par leurs concurrents afin de générer des avantages associatifs. Ces situations soulèvent des questions qui relèvent à la fois du droit de la concurrence déloyale et du droit de la propriété intellectuelle. La réponse appropriée ne doit pas se limiter à des questions techniques de priorité ou de subordination des normes défensives, mais doit dûment tenir compte de la conception fondamentale de ces deux domaines du droit et de leur interaction. Une décision récente du tribunal de commerce de Berne donne lieu à cette réflexion.
Histopathological Study of Gastric Lesions and its Correlation with Mucin Histochemistry and Helicobacter Pylori Infection
Authors: Deka Alankrita , Sharma Adity , Bhuyan Ratna K , Paul Sanjay LN 
Published: July 2021

Background: Gastric disorders are responsible for a great deal of mortality and morbidity and are one of the most common encountered problems in clinical practice. H. Pylori infection is responsible for majority of acid peptic disease and is also a known carcinogen. Intestinal metaplasia is considered a precancerous lesion. We studied the incidence of H. pylori infection and mucin histochemistry of different gastric lesions.
Methods: This study was conducted for a period of 1 year, in 50 gastric specimens received for histopathological study in the Department of Pathology, AMCH. Slides were stained with routine H&E and Giemsa for H. pylori detection. PAS/AB stain (at pH 2.5 & pH 1.0) was done to study mucin histochemistry.
Results: Out of 50 cases, 58% cases were malignant and 42% cases were benign. H. Pylori was seen in 42% cases. IM was observed in 40% of gastric lesions. IM was more common in malignant lesions. On subclassification, Type 1 and 2 IM were seen almost equally in both benign and malignant gastric lesions, but Type 3 IM was more common in malignant lesion. Incidence of IM was higher in intestinal than diffuse adenocarcinoma. A statistically significant association was seen between H. Pylori infection and IM.

Conclusion: Routine detection of H. pylori by special stains and mucin study in all gastric biopsy specimens helps in early detection of precancerous gastric lesions.
Impact of Haemodialysis on Coagulation Profile in Chronic Kidney Disease
Authors: Raja Veena , Ganapathy Shivashekar , Karthikean Suresh Kumar , Das Prakash Pradhiksha 
Published: July 2021

Background
Chronic kidney disease (CKD) with its high prevalence, morbidity and mortality is an important public health problem. Considering the nature of the haemodialysis process, it has a considerable impact on the coagulation profile. To find out the variations in Platelet count, Prothrombin time (PT), International Normalised Ratio (INR) and Activated Partial Thromboplastin Time (aPTT) before and after haemodialysis patients.
Materials and Methods:
This prospective observational study of Coagulation profile and platelet count in pre and post hemodialysis patients with chronic renal failure was conducted on 150 CKD patients in the Department of Pathology, SRM Medical College Hospital & Research Centre. p value <0.05 was considered to be statistically significant.
Results
In this study, there was significant reduction in platelet count from mean 2.29 cells/cu.mm in pre dialysis to 2.03 cell/cu.mm in post dialysis. There was a significant prolongation in both PT and aPTT values in post dialysis
Conclusion
These findings expose CKD patients to higher risk of bleeding disorders, which may have a role in increasing the rate of patient mortality and morbidity. In the light of this study, there is a need for nephrologist to monitor the coagulation profile and platelet count of CKD patients on dialysis, and treat any derangements in the same, so as to improve outcome for these patients.
Leptomeningeal Metastasis from Carcinoma Breast: A Case of Unknown to Known
Authors: Soman Princy S , A Hemalatha , R Kalyani , V Lakshmaiah 
Published: July 2021

Leptomeningeal metastasis is known to occur as an initial presentation in solid tumors. The presentation of meningeal symptoms before the diagnosis of primary tumor is seen in 10-20% cases. Though the sophisticated radiological imaging is available, Cerebrospinal Fluid (CSF) analysis for tumor cells remains the gold standard method for diagnosis. Incidence of brain metastasis from primary carcinoma breast is about 3-8% only.
We present a case of young female who presented with neurological symptoms and misdiagnosed as meningitis on Magnetic Resonance Imaging (MRI), but later after CSF analysis it was diagnosed as metastases from carcinoma breast.
Glomeruli Sparing Pattern of Unclassified Renal Cell Carcinoma: A Rare Neoplasm
Authors: Nagarajan Deepa , Mallya Mrinal , Shah Mita 
Published: July 2021

Unclassified renal cell carcinoma (URCC), an aggressive form of renal cell carcinoma (RCC), represents 0.7– 5 .7% of renal tumours. Glomerular sparing in renal neoplasms (GS) is defined as a unique growth pattern in which tumour cells overrun intact glomeruli.
An elderly woman presented with symptoms of left flank pain for three months along with fullness in the abdomen. On clinical and radiological examination, a renal mass was revealed and operated upon. A diagnosis of URCC with a glomerular sparing pattern was made on histopathological examination. The pathological details of this rare neoplasm are presented in this article.
Myoid Hamartoma of Breast - A Rare Mesenchymal Lesion
Authors: Joseph Elizabeth , Joseph Dahlia , Thomas Blessy Mary , Joy Jaison Verghese 
Published: July 2021

Hamartoma is a local malformation resulting from faulty development in an organ. It was first described in breast in 1971 by Arrigoni et al and its occurrence in breast is very rare. This tumor is composed of breast lobules admixed with fibrous tissue and fibroadipose tissue. Myoid hamartoma, also called as muscular hamartoma , is composed of smooth muscle cells in addition to ducts, lobules, and stroma. Here, we report a case of myoid hamartoma which occurred in a 53year old lady with a lump in the right breast.
A capacitação dos professores tutores no programa pec-formação universitária através dos desafios da prática
Authors: Carneiro Maria Ângela Barbato , Sarti Hilda Lúcia Cerminaro 
Published: July 2021

O objetivo deste trabalho foi identificar, entre os professores tutores do PEC- Formação Universitária, os desafios encontrados na prática e detectar os desafios por ele provocados.Para alcançar este objetivo se utilizou uma metodologia qualitativa baseada no registro de depoimentos e entrevistas.
O trabalho desenvolveu-se em três etapas. A primeira consistiu no registro da declaração dos sujeitos obtidos durante as três primeiras reuniões mensais do projeto. A segunda teve a coordenação atuando como apoio através de reuniões ocorridas nos diversos locais de trabalho. A terceira etapa se concretizou por meio de entrevistas semi-estruturadas, buscando identificar quais os problemas ainda se mantinham, as soluções encontradas e os avanços conseguidos.
Verificou-se, no final, que os sujeitos haviam aprendido a utilizar novos espaços de aprendizagem além de terem se preparado melhor através do aprofundamento de estudos e do trabalho em grupo.
O papel dos valores religiosos em escolas públicas do interior paulista.
Authors: Lima Aline Pereira , Menin Maria Suzana de Stefano 
Published: July 2021

Pretendeu-se com esta pesquisa verificar a presença e uso de valores religiosos em salas segunda e terceira série, de escolas públicas de Presidente Prudente. Buscou-se investigar como professores lidam com valores religiosos e os motivos pelos quais isto é feito. Inicialmente foram escolhidas dez escolas, onde observou-se dez salas de segunda e dez salas de terceira série em diferentes períodos. Posteriormente, tendo como foco quatro escolas onde a incidência do uso de valores religiosos foi maior, constatou-se que os valores religiosos se fazem presentes nas escolas com as mais diversas finalidades, sendo as principais, disciplinar e moralizar.

Abstract:
This search aims to verify the presence and use of religious values in second and third grades of public schools in Presidente Prudente. The aim was to investigate how teachers deal with religious values and the reasons why this is done. Initially ten schools were chosen, where it was observed ten classrooms of second grade and ten third grades of rooms of different periods. Later, focusing on four schools where the incidence of religious values were higher, we concluded that these values were applied for diverse reasons, mainly, disciplinary and morality purposes.
Evolução do conceito de tecnologia em professores do ensino fundamental durante aplicação do projeto teckids
Authors: Veraszto Estéfano Vizconde , Silva Dirceu da , Miranda Nonato Assis de , Simon Fernanda de Oliveira 
Published: July 2021

O avanço tecnológico modifica hábitos e valores ao mesmo tempo em que antigos paradigmas estabelecidos têm sido colocados em xeque. O professor que antes dominava todo o conteúdo tem dado lugar a um novo tipo de profissional capaz de mobilizar os conhecimentos transformando-os em ação. Atualmente sentimos a necessidade de um professor capaz de organizar situações de aprendizagem com autonomia ao mesmo tempo em que seja capaz de refletir acerca de sua própria ação. Ao longo deste trabalho apresentaremos a forma como foi desenvolvido uma proposta de capacitação de Educação Tecnológica para professores do Ensino Fundamental, ao mesmo tempo em que pudemos classificar e analisar as opiniões que os mesmos apresentaram e como essas opiniões evoluíram durante o desenvolvimento do trabalho. Este levantamento é fundamental para se estabelecer um consenso, visto que a tecnologia é tratada de maneira bastante diversificada e na maioria das vezes de forma errônea.

Abstract:
The technological breakthrough modifies habits and values at the same time that the established old paradigms have been in doubt. The teacher who first dominated the entire content has given rise to a new type of professional capable of mobilising the knowledge transforming them into action. Nowadays we need a kind teacher who capable of organizing situations of learning with autonomy and the same time, someone able to reflect on their own actions. Throughout this work we will present the way that was developed a proposal of Technological Education training for teachers of the elementary school at the same time that we classify and analyse the views they had and how these views have developed during the survey. This survey is crucial to establish a consensus, since the technology is seen through fairly diversified lenses and most of the time in an erroneous perspective.
Trabalho docente: uma categoria ontológica
Authors: Almeida José Luís Vieira de 
Published: July 2021

O objetivo geral do trabalho que permitiu a elaboração deste texto é compreender as mediações que se estabelecem entre docentes e estudantes como constituintes do trabalho docente. Trata-se de um trabalho de cunho teórico e bibliográfico. Discute-se, em primeiro lugar, o trabalho compreendendo-o como uma mediação. Em seguida, examina-se a mediação com base nas filosofias de Hegel, Marx, Lukács e Mészáros, portanto, numa perspectiva dialética. Inicia-se o exame da categoria em Hegel que a desenvolveu, passando-se, em seguida, a discuti-la em Marx que a compreendeu na perspectiva da Ontologia do Ser Social. Os outros autores a abordaram visando a análise do referencial marxista. Na segunda parte do texto, aborda-se a mediação como categoria ontológica e como referência para compreender o trabalho docente. Conclui-se o texto discutindo-se as possibilidades de
desenvolvimento dessa perspectiva teórica como práxis na sala de aula e destacando-se a necessidade de compreender a categoria trabalho docente como uma mediação ontológica.
A orientação sexual no contexto inclusivo: um estudo teórico
Authors: Leão Andreza Marques de Castro , Ribeiro Paulo Rennes Marçal 
Published: July 2021

O intuito do presente estudo é esboçar e refletir a questão da orientação sexual no cenário inclusivo. As fontes deste trabalho são artigos, dissertações, teses e livros que versam sobre os
temas da inclusão e sexualidade, aspectos estes inter-relacionados e indissociáveis. O assunto da sexualidade é um dos muitos que pode facilitar o processo de inclusão das pessoas com deficiências, pois está associada muito mais com o trabalho de expressão de sentimentos, atitude e de formação de valores morais, do que com conteúdos acadêmicos e científicos a ser dominado intelectualmente pelos alunos. Deste modo, a inserção da orientação sexual no contexto escolar decorre da necessidade de se propiciar uma educação geral dos alunos, a qual inclua a sexualidade. Os alunos detentores dos seus direitos precisam ter oportunidades de saber sobre a
sexualidade, de modo que tenham acesso às informações precisas que envolvam este tema, a fim de que não sejam reféns dos mitos e tabus. Para o êxito da inclusão dos alunos com deficiências implica em se considerar a sexualidade, visto que é uma necessidade básica do ser humano. Portanto, é mister políticas públicas e programas educacionais eficazes, que se atenham à relevância da orientação sexual ser efetivada no cenário escolar, de modo que todos estudantes inseridos nos bancos escolares possam desfrutar de uma educação inclusiva, a qual não exclua, mas sim inclua a sexualidade.
Conversando sobre a sexualidade adolescente – curso on-line para comunidade de educadores e educadoras do município de Presidente Prudente – SP
Authors: Mendes Patricia de O. e S. Pereira 
Published: July 2021

Compreender a adolescência em seus aspectos sócio-culturais, bem como dialogar a respeito da temática sexualidade e a forma como ela passa a ser encarada nesta etapa de
desenvolvimento humano, é de fundamental importância na formação de educadores e educadoras. O presente Projeto de Extensão faz parte da caminhada do Grupo de Pesquisa
Formação de Educadores e Educação Sexual da UDESC, que há mais de vinte anos desenvolve suas atividades aliando ensino, pesquisa e extensão, com a preocupação atual de estudar o uso das novas tecnologias. Esse curso on-line, direcionado aos educadores e educadoras do município de Presidente Prudente e demais educadores público interno da Universidade do Estado de Santa Catarina - UDESC, objetivou sensibilizar esses profissionais para a urgência de realizarem reflexões diante da adolescência e da sexualidade adolescente, com vistas à construção de ações comprometidas com uma educação sexual emancipatória. A metodologia on-line foi desenvolvida na plataforma MOODLE, que se caracteriza como um ambiente virtual de aprendizagem livre e envolveu a leitura de conteúdos distribuídos em módulos específicos, na realização de exercícios reflexivos a respeito do adolescente que o educador foi e do adolescente que esse educador educa. Os resultados apontados pelos docentes a partir das reflexões realizadas no curso revelaram uma maior sensibilização para temática, um interesse em aprofundamentos teórico metodológicos a respeito da adolescência e da sexualidade, assim como o planejamento de ações direcionadas para a implementação de propostas intencionais de educação sexual emancipatória nos espaços educativos onde atuam esses profissionais.