bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comparative Study on Antioxidant and Cytotoxic Potentials of Methanol Extract of Jatropha curcas Seeds and Leaves
Authors: Sulaimon Lateef Adegboyega , Ola-Mudathir Fausat Kikelomo , Abdullahi Bunyamin Alhassan , Mukhtar Ahmad Ila , Obuotor Efere Martins 
Published: December 2021

Many medicinal plants have been reported to exhibit protective effects against many physiological diseases as a result of their phytochemical components which are effective antioxidants. This study was aimed at comparing the phenolic and flavonoids contents, antioxidant and cytotoxic activities of methanol extract of Jatropha curcas seeds and leaves. The cytotoxicity level of J. curcas was assessed using the brine shrimp lethality test (BSLT). The antioxidant activity was determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, ferric reducing antioxidant power (FRAP), nitric oxide scavenging activities, 2, 2’-azino-bis-(3 ethyl benzothiazoline-6-sulphonic acid (ABTS) + scavenging activities and total antioxidant capacity. The total flavonoids and total phenols content (TPC) were carried out using aluminum chloride and Folin-Ciocalteu assay respectively. The results showed that J. curcas leaves have significant higher phenolic and flavonoids contents than the seeds. The total antioxidant capacity and FRAP were also significantly higher in the leaves than the seeds of J. curcas. Furthermore, the DPPH, ABTS and Nitric oxide scavenging activities were significantly higher in the leaves than the seeds. The J. curcas leaves have a higher LD50 than the seeds. In conclusion, this study suggests the antioxidant potency as well as the safety of the crude methanol extract of the leaves of J. curcas over the seeds.
Keywords: Jatropha curcas, antioxidant, cytotoxicity, flavonoids, brine shrimp lethality test, total phenolic compounds
Implementation of the National Project «Labor Productivity and Employment Support» in the Perm Region: Facts, Problems, Prospects
Authors: Alexandrova T. V. , Popov V. L. 
Published: December 2021

In the context of the reorientation of the Russian economy towards an innovative development path, the issue of increasing labor productivity has become an important part of state policy.Currently, the country is implementing a large-scale national project «Labor productivity and employment support». The implementation of the project approach to managing labor productivity for the Russian economy is of strategic priority, since its application helps to increase the efficiency of resource use, realize the goals of modernizing production, and stimulate innovation and export activities of domestic enterprises.The aim of the study is to consider the regional aspect of the implementation of the priority national project «Labor productivity and employment support» on the example of the Perm region. The methodological basis of the study are comparative, statistical and expert methods.The paper analyzes the implementation of the national project «Labor productivity and employment support» in the Perm region; presents the actual results of the project; formulates problems in the implementation of project activities; identifies the prospects of the Perm region in the context of setting higher targets for the regional project «Labor productivity and employment support» in comparison with the figures for Russia as a whole.The materials outlined in this article can deepen knowledge about the specifics of the implementation of the priority national project «Labor productivity and employment support» at the regional level, as well as be used to adjust the course implementation of a regional project aimed at improving productivity in the Perm region.
Pengembangan Aplikasi Bank Darah Pada Palang Merah Indonesia(PMI) Jakarta Barat Berbasis Web
Authors: Sartika Sari Yunita , Hamidah Nasution Irma 
Published: December 2021

The blood bank application is a website-based application that is used to manage blood stock supplies and provide information related to blood donor raising schedules. Blood banking is a process to ensure that donated blood is safe and in accordance with medical procedures. The Indonesian Red Cross (PMI) is an agency that manages blood transfusions and donors throughout Indonesia. The existence of PMI is very much needed by the community, especially in the need for blood stocks when in an emergency situation and requires blood transfusions. For this reason, an application is needed that can assist in the process of blood donation activities. The analytical method used is the PIECES method (Performance, Information, Economics, Control, Efficiency, and Service) and the system development method using the prototype method. The results of the development of this system are optimizing the process of managing blood stocks and information related to the schedule for raising blood donors, as well as improving the performance of officers in managing blood bank data. Keywords: Application, Website, Blood Bank, Blood Donor, PMIABSTRAK Aplikasi Bank darah adalah aplikasi berbasis website yang digunakan untuk mengelola persediaan stok darah dan memberikan informasi yang terkait dengan jadwal penggalangan donor darah. Bank darah merupakan proses untuk memastikan bahwa darah yang disumbangkan aman dan sesuai dengan prosedur medis. Palang Merah Indonesia(PMI) merupakan instansi yang mengelola transfusi dan donor darah diseluruh Indonesia. Keberadaan PMI sangat dibutuhkan oleh masyarakat, terutama dalam kebutuhan stok darah ketika dalam keadaan gawat darurat dan membutuhkan transfuse darah. Untuk itu, diperlukannya aplikasi yang dapat membantu dalam proses kegiatan donor darah. Metode Analisa yang digunakan adalah metode PIECES(Performance, Information, Economics, Control, Efficiency, and Service) dan metode pengembangan system menggunakan metode prototype. Hasil dari pengembangan sistem ini yaitu mengoptimalkan proses pengelolaan stok darah dan informasi yang terkait dengan jadwal penggalangan donor darah, serta dapat meningkatkan kinerja petugas dalam mengelola data bank darah. Kata kunci: Aplikasi, Website, Bank darah, Donor darah, PMI
Optimasi Metode AHP dengan SAW untuk Seleksi Penerimaan Karyawan Baru : Studi Kasus Verint System
Authors: Rohman Muhammad Saipul 
Published: December 2021

Proses rekrutmen karyawan baru merupakan hal yang penting bagi perusahaan. Dengan memilih kandidat yang tepat sebagai karyawan maka kegiatan operasional perusahaan bisa berjalan dengan lancar sehingga bisa bersaing dengan perusahaan lain. Bagian Human Resource merupakan salah satu bagian yang vital karena melakukan proses rekrutmen karyawan baru. Kemungkinan terjadinya resiko human error, faktor penilaian subjektivitas dan pemeriksaan berkas yang masuk satu persatu sehingga membutuhkan waktu yang tidak sebentar merupakan permasalahan utama saat proses seleksi penerimaan karyawan baru di Verint System.Metode AHP adalah salah satu metode sistem pendukung keputusan untuk menghitung bobot setiap kriteria dan metode SAW adalah salah satu metode sistem pendukung keputusan untuk merangking setiap alternatif berdasarkan setiap kriteria. Metode Exact Match digunakan untuk mengecek ketepatan kata jika ada yang sama maka kata tersebut tepat dan jika tidak ada yang sama maka kata tersebut Not Match, sedangkan Flag adalah penanda apabila benar diberi flag 1 (true) Exact Match jika tidak benar maka diberi flag / tanda 0 (not match). Metode yang digunakan dalam penelitian ini yaitu metode AHP dan optimasi metode AHP dengan SAW serta metode menghitung persentase akurasi dari metode tersebut menggunakan exact match. Berdasarkan hasil pengujian yang sudah di olah dan telah di analisis, hasil penelitian optimasi metode AHP dengan SAW menghasilkan persentase akurasi sebesar 90% lebih baik dari persentase akurasi metode AHP sebesar 10% yang membuktikan bahwa optimasi metode AHP dengan SAW membuat sistem menjadi lebih baik daripada dengan menggunakan metode AHP
BADANIE PUNKTÓW ZWROTNYCH CEN ROPY NAFTOWEJ W LATACH 2015 - 2019
Authors: Krawiec Monika , Furman Rafał 
Published: December 2021

Celem pracy była identyfikacja punktów zwrotnych cen ropy naftowej w latach 2015 – 2019, do czego zastosowano test Perrona. Następnie podjęto próbę wskazania wydarzeń o charakterze geopolitycznym, które mogły być przyczyną istotnych zmian w strukturze trendu. Wykorzystano w tym celu, publikowane na portalach biznesowych, komentarze analityków oraz raporty surowcowe. Na tej podstawie oceniono, że w większości przypadków na notowania ropy naftowej w badanym okresie najbardziej wpływały problemy z nadwyżką podaży ropy naftowej w Stanach Zjednoczonych. Raporty informujące o zwiększającej się liczbie funkcjonujących platform wiertniczych w Ameryce Północnej oraz niski popyt na rynku paliwowym często powodowały długotrwałe obniżki cen na giełdach New York Mercantile Exchange (NYMEX) i Intercontinental Exchange (ICE).
Grunnskolelærere i musikk og deres kompetanse
Authors: Nielsen Siw Graabræk , Karlsen Sidsel 
Published: December 2021

I denne artikkelen diskuteres kompetansen til lærere som underviser i musikk i den norske grunnskolen. Utgangspunktet er data hentet fra en spørreundersøkelse blant 293 lærere over hele landet. Undersøkelsen bygger på et Bourdieu-inspirert teoretisk rammeverk der det å ha tilgang til rike musikalsk-kulturelle ressurser forstås som potensielt utvidende for elevenes musikkrelaterte kapital på tvers av sosiale og kulturelle skillelinjer. Tidligere forskning viser at høy grad av faglig spesialisering hos musikklærerne er knyttet til mulighetene for å iverksette et rikt musikkfag for elevene. Lærerkompetansen i musikk i den norske grunnskolen har generelt blitt forstått som lav, men resultatene fra den rapporterte undersøkelsen viser et mer komplekst bilde av situasjonen.
English abstract
English title: The competence of compulsory school music teachers. What is the situation in the Norwegian context?
This article discusses the competence of teachers teaching music in Norwegian compulsory education. It takes as its point of departure data gathered through a survey among 293 teachers located across the country. The theoretical framework is Bourdieu-inspired and emphasises access to rich musical and cultural resources as potentially enhancing for students’ music-related capital across social and cultural divides. Previous research shows that a high degree of subject-specific specialisation among music teachers is coupled with the possibilities of implementing a rich music subject for the students. While teacher competence in music in Norway has generally been understood as low, the findings from the survey reported here show a more complex picture of the situation.
Effect of L-Carnitine on the Indices of endothelial Dysfunction and Inflammation Factors in Patients with Acute Myocardial Infarction Without the Q Wave
Authors: B. A. Aliavi  , Sh. A. Iskhakov  , Sh. K. Muminov  , A. K. Tursunbaiev  , P. M. Tolipov  , M. G. Muhamedova  
Published: December 2021

Aim: To evaluate the influence of L-carnitine on inflammatory markers and indicators of endothelial function in patients with acute myocardial infarction without the Q wave.Materials and Methods: 40 patients with verified diagnosis of AMI without Q-wave. All the patients were matched by sex, age, weight and duration of the underlying disease. The patients were randomized into 2 groups. The first group ofpatients were on a standard basic therapy and additionally administered L- carnitine at a dose 5g/day, II- group consisted of patients who did not receive drugs with metabolic action. In dynamics (on the 1st and 10th day of the treatment) the parameters of endothelium vasodilation and markers of inflammation were evaluated.Results: On the background of the basic therapy in both groups an improvement in endothelial function resulting in an increase of brachial artery diameter was observed. However, the L- carnitine vasodilator effect was more pronounced and persistent as compared to group II. In the dynamics, CRP levels and plasma fibrinogen were more pronounced in the Ist group.
Growth-differentiation factor 15, N-terminal pro-brain natriuretic peptide, structural and functional changes of the heart in patients with heart failure and normal ejection fraction after myocardial infarction on the background of arterial hypertension
Authors: V. D. Syvolap  , Ya. V. Zemlianyi  
Published: December 2021

Levels of GDF-15, NTproBNP, structural and functional changes of the heart were assessed in 69 patients with postinfarction cardiosclerosis and preserved left ventricular ejection fraction (EF>45 %). We found out that patients with heart failure and preserved ejection fraction after myocardial infarction on the background of arterial hypertension have increased levels of GDF 15 and NTproBNP. These biomarkers were correlated with left ventricular diastolic dysfunction and left atrial volume index.
Platelet-vessel hemostasis in patients with myocardial infarction depending on allelic variants of genes ACE (I/D) and eNOS (894G>T). Treatment effect
Authors: J. V. Ursuliak  , L. P. Sydorchuk  
Published: December 2021

Changes in the platelet-vascular hemostasis influenced by basic treatment of 102 patients with acute myocardial infarction (AMI) depending on allelic variants of genes angiotensin-converting enzyme (ACE, I/D) and endothelial NO-synthase (eNOS, 894G> T) have been analyzed. The dependence of the treatment efficacy on genotypes and haplotypes of the analyzed genes in relation to hemostasis key-chains has been established.
Corrective influence of ademol on metabolism of nitrogen monoxide in the brain of the rats with modeling cerebral ischemia
Authors: O. A. Khodakovskiy  , A. Y. Khodakovskiy  
Published: December 2021

In experiments on the rats with model of acute disorder of encephalic circulation (bilateral carotid occlusion) it was established that introduction of derivate of adamantan 1-adamantilethyloxy-3-morpholino-2 propanol hydrochloride (under conventional name ademol) in dose 2 mg/kg intraabdominal in treatment mode (in an hour after insult and further 1 time a day after every 24 hours during 21 days of cerebral ischemia) better than cerebroprotector citicoline provides decreasing of activity of general NOsynthase (NOS) in the rats’ brain, on which indicated reduced content of stable metabolite of NO and preservation of L-arginine (L-Arg) pool. Such effect of ademol can be one of the key mechanisms of its protective influence on ischemic neurons of the brain and indicate a perspective for creation on its base a new cerebroprotector agent.
Correction of Hepatic Encephalopathy in Patients with Liver Cirrhosis in Combination with Intestinal Dysbiosis
Authors: I. M. Havrysh  
Published: December 2021

65 patients with liver cirrhosis combined with intestinal dysbiosis have been examined; an assessment ofthe functional state of the liver, clinical manifestations of hepatic encephalopathy, neuropsychometric tests, intestinalmicrobiota has been carried out; Lactobacillus and Bifidobacterium as well as Methylsiliconic acid hydrogel were included into the complex treatment. Inclusion of these drugs in the complex treatment resulted in significantly better reduction of subjective and objective signs of cirrhosis, severity of functional and biochemical syndromes, symptoms of hepatic encephalopathy.
Methodical approaches to teaching chemistry for the preparatory department for Ukrainian citizens in Bukovinian state medical university
Authors: O. O. Perepelytsia  
Published: December 2021

Methodical approaches to teaching chemistry under conditions of limited amount of teaching hours for students with different learning abilities that are studying at the preparatory department for Ukrainian citizens of Bukovinian medical university are considered in this article. Based on the results of mental activity diagnosis for each group of teenagers methodical techniques for working with students were developed. It is proposed to use explanatory, illustrative training with problematic elements while teaching basic, principal topics, and for the sections that are a logical conclusion of basic topics to use the method of proactive knowledge for the groups of students with creative and constructive mindset. Systematization and structuring of studied material should be conducted through usage of graph-logic schemes and tables. It is advisable to practice skills in all groups of students regardless of their level of knowledge wherein for the groups with creative and constructive mindset tasks modeled from real situations and problems of increased complexity should be solved. Extracurricular independent work should be organized with different learning abilities of students taken in mind by developing tasks that are differentiated by their difficulty rate.
IMPLEMENTASI PROGRAM PEMENTASAN KEMISKINAN DI DESA LOLI OGE KECAMATAN BANAWA KAB. DONGGALA
Authors: Pettalongi Adawiyah , Hasriani  , N. Samani Moh. Israwan 
Published: December 2021

Salah satu tanggungjawab pemerintah desa adalah pementasan kemiskinan di wilayah yang merupakan kewenanganya. Pementasan kemiskinan dilaksanakan dengan merealisasikan program-program pementasan kemiskinan sesuai dengan regulasi yang telah ditetapkan oleh pemerintah pusat. Karena itu penelitian ini bertujuan menganalisis pelaksanaan program pemetasan kemiskinan di Desa Loli Oge, kecamatan Banawa, Kabupaten Donggala. Penelitian ini menggunakan metode kualitatif deskriftif berdasarkan data-data yang diperoleh. Tujuan penelitian ini adalah bagaimana Implementasi program pementasan kemiskinan oleh pemerintah Desa, serta faktor penghambat dan pendukung dalam pelaksanaannya. Informan dalam penelitian ini adalah Kepala Desa, Ketua BPD, Sekertaris Desa, Kasi bidang pemberdayaan dan Masyarakat. Data-data yang terkumpul diperoleh melalui tekhnik wawancara, observasi dan dokumentasi. Tahapan analisis data dilakukan dengan memverifikasi data-data yang dibutuhkan sesuai dengan masalah penelitian, kemudian data disusun, dan disajikan serta tahap terakhir penarikan kesimpulan. Hasil penelitian menunjukkan bahwa Pemerintah Desa lili Oge dalam mengimplementasikan Program pementasan kemiskinan dengan langkah melakukan sosialisasi selanjutnya dilakukan pemetaan terhadap masyarakat mana yang berhak dan yang tidak berhak (DTKS dan Non-DTKS) dengan melibatkan partisipasi masyarakat dalam penetapannya, serta melakukan pengkategorian sesuai dengan aturan dan juknis yang telah ditetapkan. Dalam tataran penyaluran program melibatkan masyarakat dan seluruh stockholder yang berwenang didalam penyaluran program pementasan kemiskinan tersebut, upaya tersebut sangat relevan dengan Strategi dalam upaya mencapai tujuan dan sasaran serta kebijakan program pementasan kemiskinan yaitu strategi partisipasi.
Modernisation of urban governance: An approach of ‘Blockchain + Big Data’
Authors: Xiao Xiao-Yong , Jin Lin , Kateb Faris , Ahmed Aldeeb Hooreya Mohamed 
Published: December 2021

Abstract
Mathematics is a prerequisite for the development of blockchain technology. The deeply penetrated mathematical ideas support the establishment of the trust mechanism of the whole blockchain system, which makes the blockchain technology autonomous, decentralised, not so easy to tamper, open, anonymous and also possesses other characteristics. Due to these characteristics, the introduction of blockchain will greatly solve a series of problems faced by the quality and acquisition of big data in cities, and release more data vitality. Based on the perspective of chain blocks and big data fusion, this paper puts forward that data are the foundation of modern urban governance. Data management has become the key to modern urban governance. It puts forward that the building of a big data management system based on blockchain will strengthen the construction of the intelligent city and modernisation of urban governance capabilities.
Nutritional status and dietary behaviours of Northern Algeria university students
Authors: Aidoud A. , Elahcene O. , Bravo R. , Ugartemendia L. 
Published: December 2021

Abstract
The present study tries to assess the nutritional status and dietary behaviours in a group of undergraduate students in order to characterize their food habits and assess the quality of their diet. A cross-sectional study was conducted with 220 undergraduate university students (110 male and 110 female) aged between 19 and 24 years from the Food Department of Saad Dahlab Blida 1 University (Algeria). The data collection and nutritional evaluation were carried out using DIAL nutritional software. Male participants had significantly (P < 0.005) higher body mass index (BMI) when compared to females. Significantly higher percentages of female students (P < 0.005) had tried a low-fat diet (P = 0.0075) and a low-carbohydrate diet (P < 0.005). The prevalence of overweight was higher among males compared to females. In contrast, a greater percentage of underweight students were observed in the group of female subjects. Related to micronutrient intake, a significant difference by sex was observed for vitamin A, C, folic acid, iron, calcium, and sodium intakes. However, females consumed more food containing vitamins C and A, whereas males’ intake of calcium, sodium, folic acid, and iron was higher than the corresponding values observed in females. To conclude, these students reported a diet characterized by a high variety of cereal products and a moderate amount of vegetables, milk and dairy products, meat, fish and eggs, dietary fats and beverages, whereas the consumption of fruits was highly infrequent.
The role of r esistant starch in human nutrition
Authors: Zurbó Zs. , Csapó J. 
Published: December 2021

Abstract
In this paper, we examine the role and effect of resistant starch (RS) in human nutrition; further, the structure and properties of RS, the food sources based on resistance to digestion in the colon, and the physiological effects of RS are described. The nutritional value of RS, the effect of RS on short-chain fatty acid (SCFA) production, the relationships between RS and colon function, and the relationships between food starch, dietary fibre, and RS content and colon cancer development are reviewed. It has been shown that the use of RS in foods may have some benefits. Resistant starch, digestion of resistant-starch-containing foods have a number of health benefits for colon function but appear to have less effect on lipid-glucose metabolism. It has a positive effect on colon bacterial activity, promotes the growth of beneficial microbes, and reduces the activity of enzymes that are harmful to the digestive system. Under the influence of RS, increased SCFA production lowers the pH of the colon and stimulates bile acid secretion. The decreased pH protects against colon cancer and inhibits the conversion of primary and secondary bile acids, which are cytotoxic to intestinal cells. At the end of the review article, the relationships between RS and the colon microflora, its use as a prebiotic, and the relationship between RS and glucose metabolism are analysed. It was found that the use of RS in the diet might have benefits as it shortens the time it takes food to pass through the colon and increases the amount of stool. It was also found that the physicochemical properties of foods can directly affect the amount of RS and thereby the blood glucose levels and insulin response.