bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studi Kelayakan Pembangunan Biodigester Limbah Cair Pabrik Tahu
Authors: Nugroho Meriana Wahyu , Hidayatuloh Suryo , Ramadhani Rahma , Primasworo Rifky Aldila 
Published: March 2021

Dampak pengolahan industri tahu adalah limbah cair yang kebanyakan menimbulkan masalah. Limbah cair tahu dapat dimanfaatkan menjadi biogas. Untuk itu perlu studi analisa kelayakan untuk pembangunan biodigester dari segi teknis, ekonomi dan lingkungan. Proses pekerjaan teknik pada analisa teknik digunakan untuk menentukan jenis digester dan penempatan yang sesuai dan efisien diperoleh dari biaya operasional, luas lahan dan kapasitas produksi. Dari survei analisa teknik didapatkan jenis instalasi reaktor yang dipilih yaitu Cover Lagoon Anaerobic Reactor (Colar) termodifikasi dengan model portable kapasitas 200 liter. Pada studi analisa ekonomi digunakan untuk mengetahui kelayakan pembangunan Biodigester dalam menentukan rincian anggaran biaya dan didapatkan harga Rencana anggaran biaya senilai Rp. 2.301.000,- dan investasi dalam jangka 5 tahun ke depan dengan parameter Net Present Value (NPV)= Rp 7.512.000,- (bernilai positif), Probality Indeks (PI)= 3,2 ≥ 1 dalam jangka investasi, Internal Rate Of Return (IRR) pada suku bunga yang berlaku secara umum NPV bernilai positif dan tidak ditemukan IRR dan Payback Periode (PP) = 1,3 Tahun (≤ jangka investasi 5 tahun) usaha kembali modal. Analisa kelayakan lingkungan didapatkan hasil bahwa outer biodigester aman dan bau sedikit menyengat serta berkurangnya limbah cair pabrik tahu, penanganan dari outer tersebut adalah di jalur khusus ke drainase tertutup atau pipa ke tempat pembuangan akhir atau tangki septik tertutup. ABSTRACTThe impact of the tofu processing industry is their liquid waste which mostly causes problems. Tofu liquid waste can be used as biogas. For that, we need a feasibility study for the development of a Biodigester from a technical, economic, and environmental perspective. The process of technical analysis is used to determine the type of digester and the suitable and efficient place, obtained from operational costs, land area, and production capacity. From the technical analysis study, the selected type of reactor installation was obtained, namely the modified Cover Lagoon Anaerobic Reactor (Colar) with a portable model with a capacity of 200 liters. The economic analysis study is used to determine the feasibility of the Biodigester development in determining the detail of cost budget and it reached Rp. 2.301.000.00, - and the investment in the next 5 years with the parameter Net Present Value (NPV) = Rp. 7.512.000.00 (positive value), the probability Index (PI) = 3.2 ≥ 1 in the investment term, the internal Rate Of Return (IRR) is generally positive at the applicable interest rate, and there is no IRR and Payback Period (PP) = 1.3 years (≤ 5 years investment) of the return on investment. The environmental analysis study resulted that the outer biodigester is safe and smells a bit sting to reduce the liquid waste from the tofu factory. Those handling of the outer is located in a special route pipe to the final landfills site or closed septic tank.
Implementasi Pembelajaran Kontekstual dengan Strategi REACT (Relating, Experiencing, Applying, Cooperating, Dan Tranferring)
Authors: Kholisiyah Nurul , Yuanita Dianis Izztul 
Published: March 2021

Kemampuan siswa terhadap pelajaran matematika di MI perlu terus ditingkatkan, mengingat perkembangan dunia saat ini menuntut berbagai perhitungan yang lebih rumitid. Tidak terkecuali siswa di Madrasah Ibtidaiyah Daya Muda Al-Islam Takat Kampungbaru Tanjunganom Nganjuk yang saat ini masih tergolong rendah. Terlihat dari nilai ulangan semester II tahun pelajaran 2015/2016, yaitu: dari 119 siswa hanya 21% yang tuntas belajar secara klasikal (dikatakan tuntas apabila nilainya 75) sedangkan yang tidak tuntas 79%. Mengatasi permasalahan di atas, diperlukan strategi REACT yang menekankan pada aktivitas siswa secara penuh, baik fisik maupun mental.Fakus penelitian dalam tesis ini adalah: (1) Bagaimana proses pembelajaran kontekstual dengan strategi REACT pada mata pelajaran matematika di MI Daya Muda Al-Islam. (2) Kemampuan apa saja yang nampak dalam pembelajaran kontekstual dengan strategi REACT pada mata pelajaran matematika di MI Daya Muda Al-Islam. Hasil penelitian ini adalah: (1) Proses pembelajaran kontekstual dengan strategi REACT pada mata pelajaran matematika di MI Daya Muda Al-Islam dilakukan dengan 4 proses tahapan, pertama proses relating siswa diberi rumus kemudian mengaitkannya dengan kehidupan nyata, kedua proses experiencing yaitu siswa melakukan eksplorasi rumus dengan pengalaman nyata siswa, ketiga siswa menerapkan pengalaman dalam kehidupan nyata untuk memecahkan soal matematika, keempat proses cooperating siswa bersama dengan kelompoknya melakukan diskusi untuk memecahkan soal bersama-sama, kelima proses tranferring siswa melakukan presentasi dari hasil diskusi bersama kelompoknya setelah memecahkan soal matematika. (2) Kemampuan siswa yang nampak dalam pembelajaran kontekstual dengan strategi REACT pada mata pelajaran matematika di MI Daya Muda Al-Islam adalah: pertama kemampuan relating siswa sudah cukup baik hal ini dibuktikan dengan hasil tes ulangan harian.Kemampuan experiencing dengan 8 indikator sudah mencapai nilai rata-rata yang baik. Kemampuan applying dari 5 indikator,3 aspek kurang baik. Kemampuan cooperating siswa, 6 siswa dengan 5 indikator sudah menunjukkan nilai rata-rata yang baik, Kemampuan tranferring siswa rata-rata sudah baik, walaupun siswa masih berlum terbiasa mengkomunikasikan hasil diskusi dengan presentasi di depan kelas.
2. Simondon as a Neo-Scholastic?
Authors: Fredrikzon Johan 
Published: March 2021

Johan Fredrikzon spent one and a half years as a visiting research assistant at the Film and Media Studies Program at Yale University 2018/2019. Some months before he arrived, a two-day workshop on Simondon was held by the Yale-Düsseldorf Working Group on Philosophy and Media, titled Modes of Technical Objects, with scholars from the US and Germany. Fredrikzon decided to engage a few of the workshop participants for this special issue of Sensorium, with the purpose to discuss perspectives on Simondon as a theoretical instrument for thinking technology, how the French philosopher matters in their work, and why there seems to be a revival in the interest in the writing of Simondon these days. On behalf of the Sensorium journal, the interviewer would like to thank the three interviewees for their generous participation.
About John Durham Peters:
John Durham Peters is María Rosa Menocal Professor of English and of Film & Media Studies at Yale University. Peters has been a creative force in media studies for many years and his thinking continues to influence academic environments throughout the world. His book The Marvelous Clouds: Toward a Philosophy of Elemental Media (Chicago, 2015) was an attempt to rethink the concept of media by including weather, dolphins and fire to the infrastructural landscape of digital communications and climate change. His new book, in cooperation with Kenneth Cmiel, is called Promiscuous Knowledge: Information, Image, and Other Truth Games in History (Chicago, 2020).
Multimodal Analysis of the Tissue Response to a Bone-Anchored Hearing Implant: Presentation of a Two-Year Case Report of a Patient With Recurrent Pain, Inflammation, and Infection, Including a Systematic Literature Review
Authors: Johansson Martin L. , Calon Tim G.A. , Omar Omar , Shah Furqan A. , Trobos Margarita , Thomsen Peter , Stokroos Robert J. , Palmquist Anders 
Published: March 2021

Osseointegration is a well-established concept used in applications including the percutaneous Bone-Anchored Hearing System (BAHS) and auricular rehabilitation. To date, few retrieved implants have been described. A systematic review including cases where percutaneous bone-anchored implants inserted in the temporal bone were retrieved and analyzed was performed. We also present the case of a patient who received a BAHS for mixed hearing loss. After the initial surgery, several episodes of soft tissue inflammation accompanied by pain were observed, leading to elective abutment removal 14 months post-surgery. Two years post-implantation, the implant was removed due to pain and subjected to a multiscale and multimodal analysis: microbial DNA using molecular fingerprinting, gene expression using quantitative real-time polymerase chain reaction (qPCR), X-ray microcomputed tomography (micro-CT), histology, histomorphometry, backscattered scanning electron microscopy (BSE-SEM), Raman spectroscopy, and fluorescence in situ hybridization (FISH). Evidence of osseointegration was provided via micro-CT, histology, BSE-SEM, and Raman spectroscopy. Polymicrobial colonization in the periabutment area and on the implant, including that with Staphylococcus aureus and Staphylococcus epidermidis, was determined using a molecular analysis via a 16S-23S rDNA interspace [IS]-region-based profiling method (IS-Pro). The histology suggested bacterial colonization in the skin and in the peri-implant bone. FISH confirmed the localization of S. aureus and coagulase-negative staphylococci in the skin. Ten articles (54 implants, 47 patients) met the inclusion criteria for the literature search. The analyzed samples were either BAHS (35 implants) or bone-anchored aural epitheses (19 implants) in situ between 2 weeks and 8 years. The main reasons for elective removal were nonuse/changes in treatment, pain, or skin reactions. Most samples were evaluated using histology, demonstrating osseointegration, but with the absence of bone under the implants’ proximal flange. Taken together, the literature and this case report show clear evidence of osseointegration, despite prominent complications. Nevertheless, despite implant osseointegration, chronic pain related to the BAHS may be associated with a chronic bacterial infection and raised inflammatory response in the absence of macroscopic signs of infection. It is suggested that a multimodal analysis of peri-implant health provides possibilities for device improvements and to guide diagnostic and therapeutic strategies to alleviate the impact of complications.
Selenium Kinetics in Humans Change Following 2 Years of Supplementation With Selenomethionine
Authors: Patterson Blossom H. , Combs Gerald F. , Taylor Philip R. , Patterson Kristine Y. , Moler James E. , Wastney Meryl E. 
Published: March 2021

BackgroundSelenium (Se) is a nutritionally essential trace element and health may be improved by increased Se intake. Previous kinetic studies have shown differences in metabolism of organic vs. inorganic forms of Se [e.g., higher absorption of selenomethionine (SeMet) than selenite (Sel), and more recycling of Se from SeMet than Sel]. However, the effects on Se metabolism after prolonged Se supplementation are not known.ObjectiveTo determine how the metabolism and transport of Se changes in the whole-body in response to Se-supplementation by measuring Se kinetics before and after 2 years of Se supplementation with SeMet.MethodsWe compared Se kinetics in humans [n = 31, aged 40 ± 3 y (mean ± SEM)] studied twice after oral tracer administration; initially (PK1), then after supplementation for 2 y with 200 µg/d of Se as selenomethionine (SeMet) (PK2). On each occasion, we administered two stable isotope tracers of Se orally: SeMet, the predominant food form, and selenite (Na276SeO3, or Sel), an inorganic form. Plasma and RBC were sampled for 4 mo; urine and feces were collected for the initial 12 d of each period. Samples were analyzed for tracers and total Se by isotope dilution GC-MS. Data were analyzed using a compartmental model, we published previously, to estimate fractional transfer between pools and pool masses in PK2.ResultsWe report that fractional absorption of SeMet or Sel do not change with SeMet supplementation and the amount of Se absorbed increased. The amount of Se excreted in urine increases but does not account for all the Se absorbed. As a result, there is a net incorporation of SeMet into various body pools. Nine of the 11 plasma pools doubled in PK2; two did not change. Differences in metabolism were observed for SeMet and Sel; RBC uptake increased 247% for SeMet, urinary excretion increased from two plasma pools for Sel and from two different pools for SeMet, and recycling to liver/tissues increased from one plasma pool for Sel and from two others for SeMet. One plasma pool increased more in males than females in PK2.ConclusionsOf 11 Se pools identified kinetically in human plasma, two did not increase in size after SeMet supplementation. These pools may be regulated and important during low Se intake.
Gene Expression Signature of Traumatic Brain Injury
Authors: Ma Yawen , Liu Yunhui , Ruan Xuelei , Liu Xiaobai , Zheng Jian , Teng Hao , Shao Lianqi , Yang Chunqing , Wang Di , Xue Yixue 
Published: March 2021

Background: Traumatic brain injury (TBI) is a brain function change caused by external forces, which is one of the main causes of death and disability worldwide. The aim of this study was to identify early diagnostic markers and potential therapeutic targets for TBI.Methods: Differences between TBI and controls in GSE89866 and GSE104687 were analyzed. The two groups of differentially expressed genes (DEGs) were combined for coexpression analysis, and the modules of interest were performed using enrichment analysis. Hub genes were identified by calculating area under curve (AUC) values of module genes, PPI network analysis, and functional similarity. Finally, the difference in immune cell infiltration between TBI and control was calculated by ssGSEA.Results: A total of 4,817 DEGs were identified in GSE89866 and 1,329 DEGs in GSE104687. They were clustered into nine modules. The genes of modules 1, 4, and 7 had the most crosstalk and were identified as important modules. Enrichment analysis revealed that they were mainly associated with neurodevelopment and immune inflammation. In the PPI network constructed by genes with top 50 AUC values in module genes, we identified the top 10 genes with the greatest connectivity. Among them, down-regulated RPL27, RPS4X, RPL23A, RPS15A, and RPL7A had similar functions and were identified as hub genes. In addition, DC and Tem were significantly up-regulated and down-regulated between TBI and control, respectively.Conclusion: We found that hub genes may have a diagnostic role for TBI. Molecular dysregulation mechanisms of TBI are associated with neurological and immune inflammation. These results may provide new ideas for the diagnosis and treatment of TBI.
Analysis on Efficacy of Chitosan-Based Gel on Bone Quality and Quantity
Authors: Jayash Soher Nagi , Hashim Najihah Mohd , Misran Misni , Ibrahim Norliza , AL-Namnam Nisreen Mohammed , Baharuddin N. A. 
Published: March 2021

Objectives: To assess and compare the quantity and the quality of the newly bone generated when using chitosan-based gel scaffold and osteoprotegerin-chitosan gel scaffold.Methods: A total of 18 critical-sized defects on New Zealand white rabbit craniums were created. In 12 defects, either chitosan gel or osteoprotegerin-chitosan gel was implanted the last six defects were kept unfilled as a control. Bone formation was examined at 6 and 12 weeks. Bone’s specimens were scanned using the High-resolution peripheral quantitative computed tomography. Histological and histomorphometric analysis were carried out to compare the volume and area of regenerated bone.Results: The results of the HR-pQCT showed that bone volume and densities in the osteoprotegerin-chitosan gel group were significantly higher than the chitosan gel and control groups whereas, the bone volume density in the chitosan gel group was significantly higher than the control group in both intervals time (p = 0.01, p = 000). No significant difference in bone volume between the chitosan gel and control groups (p = 0.506, p = 0.640) was observed. However, similar findings were shown in the histomorphometric analysis, with the highest new bone formation was observed in the OPG-chitosan gel group followed by the chitosan group. The mean percentage of new bone was greater at 12 weeks compared to 6 weeks in all groups.Conclusions: Chitosan-based gel demonstrated a significant bone quantity and quality compared to unfilled surgical defects. Consistently, osteoprotegerin enhanced the chitosan gel in bone regeneration.
ICD-10-Coding of Medically Unexplained Physical Symptoms and Somatoform Disorders—A Survey With German GPs
Authors: Pohontsch Nadine J. , Zimmermann Thomas , Lehmann Marco , Rustige Lisa , Kurz Katinka , Löwe Bernd , Scherer Martin 
Published: March 2021

Background:General practitioners (GPs) are reluctant to use codes that correspond to somatization syndromes.Aim:To quantify GPs' views on coding of medically unexplained physical symptoms (MUPS), somatoform disorders, and associated factors.Design and Setting:Survey with German GPs.Methods:We developed six survey items [response options “does not apply at all (1)”—“does fully apply (6)”], invited a random sample of 12.004 GPs to participate in the self-administered cross-sectional survey and analysed data using descriptive statistics and logistic regression analyses.Results:Response rate was 15.2% withN= 1,731 valid responses (54.3% female). Participants considered themselves familiar with ICD-10 criteria for somatoform disorders (M= 4.52;SD=.036) and considered adequate coding as essential prerequisite for treatment (M= 5.02;SD= 1.21). All other item means were close to the scale mean: preference for symptom or functional codes (M= 3.40;SD= 1.21), consideration of the possibility of stigmatisation (M= 3.30;SD= 1.35) and other disadvantages (M= 3.28;SD= 1.30) and coding only if psychotherapy is intended (M= 3.39;SD= 1.46). Exposure, guideline knowledge, and experience were most strongly associated with GPs' self-reported coding behaviour.Conclusions:Subjective exposure, guideline knowledge, and experience as a GP, but no sociodemographic variable being associated with GPs' subjective coding behaviour could indicate that GPs offer a relatively homogeneous approach to coding and handling of MUPS and somatoform disorders. Strengthening guideline knowledge and implementation, and practise with simulated patients could increase the subjective competence to cope with the challenge that patients with MUPS and somatoform disorders present.
Management of Oral Mucositis in Children With Malignant Solid Tumors
Authors: Attinà Giorgio , Romano Alberto , Maurizi Palma , D’Amuri Sara , Mastrangelo Stefano , Capozza Michele Antonio , Triarico Silvia , Ruggiero Antonio 
Published: March 2021

IntroductionIn recent years, the use of intensive regimens for the treatment of pediatric cancer has led to a marked improvement in patient survival. However, these treatments are associated with an increase in toxic effects. Among these side effects, mucositis (inflammation of the oral cavity) significantly affect the success of treatment. The aim of this study was to assess the prevalence of mucositis in a pediatric population with solid tumor and undergoing chemotherapy, identify the risk factors that influence its occurrence, and verify the usefulness of pain rating scales.MethodsWe registered episodes of mucositis which occurred in a sample of 84 consecutive children with solid tumors between 1 January, 2012 and 30 April, 2018. The World Health Organization (WHO) oral mucositis grading scale and the modified Wong–Baker FACES Pain Rating Scale (WBS) were used to assess the severity of each episode. Moreover, data on the treatments used and blood count results were collected.ResultsThe prevalence of mucositis in our population was 50%, without statistically significant difference according to sex and a higher prevalence observed in patients aged &gt;10 years. The presence of neutropenia, higher number of cycles of chemotherapy, and co-existence of lymphomas and sarcomas were identified as factors favoring the occurrence of mucositis. The WBS showed results superimposed on the WHO oral mucositis grading scale in choosing the intensity and duration of mucositis treatment.ConclusionOral mucositis is a common complication of chemotherapy against childhood malignancies. The WHO oral mucositis scale is a valuable tool for assessing its severity in pediatric patients. Furthermore, WBS can be used as an assessment tool to establish the therapy to be adopted for patients in whom direct evaluation of the oral cavity is not possible.
Langmuir Turbulence in the Auroral Ionosphere: Origins and Effects
Authors: Akbari Hassanali , LaBelle James W. , Newman David L. 
Published: March 2021

Theory and observations of Langmuir waves and turbulence induced in the auroral ionosphere by electron beams of magnetospheric-origin are reviewed. The theoretical discussions include a brief description of the electrostatic dispersion relation, excitation of Langmuir waves by electron beams, and the stability of beam distributions. The theory of Langmuir turbulence—including the parametric decay instability and wave collapse—is also briefly discussed. The main focus of the review, however, is on the observations of Langmuir waves and turbulence in the ionosphere by in-situ and ground-based sensors. A summary of five decades of in-situ wave and particle observations is presented and combined with a collection of more recent results from ground-based instruments. The ground-based observations include signatures of Langmuir turbulence in the form of coherent echoes in incoherent scatter radar measurements; signatures of electron beams in the form of auroral morphologies recorded by high-speed, high-resolution optical imagers; and electromagnetic emissions received on the ground at high latitudes. Uniting the various observations obtained by the vastly different sensors is shown to provide further insight into the micro-scale processes that occur in the ionosphere. Also discussed in this review is the potential of the ground-based sensors to provide a broader spatial and temporal context for single-point in-situ measurements of such processes.
IDENTIFIKASI KONSEP FISIKA PADA KEARIFAN LOKAL PENGOLAHAN SAGU (PUTAK) KABUPATEN TIMOR TENGAH SELATAN
Authors: Laos Landiana E. , Tefu Meti O. F. I 
Published: March 2021

Abstrak Kearifan lokal adalah semua bentuk pengetahuan, keyakinan, pemahaman atau wawasan serta adat kebiasaan atau etika yang menuntun perilaku manusia dalam kehidupan di dalam komunitas ekologis. Pembelajaran fisika akan lebih bermakna jika dalam proses pembelajaran dikaitkan dengan kearifanlokal yang ada pada suatu tempat. Sagu (putak) adalah makanan tradisional yang diwariskan oleh nenek moyang masyarakat Santian, Kabupaten Timor Tengah Selatan semenjak dahulu kala. Metode penelitian yang digunakan adalah penelitian kualitatif fenomenologi, menggunakan teknik triangulasiberupa observasi, wawancara, dan dokumentasi. Hasil penelitian diperoleh bahwa pada proses pengolahan sagu (putak) terdapat konsep-konsep fisika yang diidentifikasi terutama pada gaya, tekanan, suhu dan kalor, momentum, proses pemisahan campuran, larutan, pengendapan,penguapan, perubahan volume.
Kata kunci: Kearifan Lokal; Konsep Fisika Abstract Local wisdom is a kind of knowledge, belief, comprehension and insight as well as habit and ethic thatleads human’s behavior in an ecology community. Physics will be meaningful learning process is related to the local wisdom in a certain context. Sagu (putak) is a kind of traditional meal which is inherited by the anchestors of Santian community, Timor Tengah Selatan from time to time. This study is a phenomenology, applying qualitative method, triangulating among observation, interview and documentation. The result showed that in processing sagu (the traditional meal), there were somephysics concepts identified particularly force, pressure, temperature and heat, momentum, mixture separation, solution, deposition, evaporation and volume change.Keywords: Local wisdom; physics concept