bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of Scie-chain Method on Students’ Academic Achievement and Attitude in Managing Large Classes in Science 10
Authors: Valiente Ma. Mheliza S. , Bascos-Ocampo Rema 
Published: March 2021

The researchers aimed to find out the effectiveness of Scie-chain method on students’ academic achievement and attitude in managing large classes in Science 10 of Flora National High School. Specifically, it identified the difference and effect to the academic achievement of students and students’ attitude towards Science of the traditional method and Scie-chain method of teaching. The researchers employed the two-group pretest- posttest quasi-experimental design which made use of the Scie-chain method (Inquiry-based, ICT utilization, and flock system) in the experimental group. The data were analyzed with the use of weighted mean. Results of the study showed thatoriginally the experimental group and the control group are equal in terms ofacademic achievement and attitude towards Science. After the intervention, the experimental group yielded better result in terms of academic achievement and attitude towards Science as Manifested in the difference in their post test. From the findings of the study, the following conclusions were drawn:1. students exposed to the Scie-chain method attained better academic achievement compared to students exposed to traditional teaching method; the intervention (Scie-chain method) enhanced the level of attitude of students towards Science; and the Scie-chain method is an effective strategy to manage large classes.
Case Study: Effect of Soybean Infusion on Blood Glucose Levels on Wistar-strain Rats Loaded with Glucose
Authors: Beyna F. Pijar , Slamet Isworo 
Published: March 2021

Background and Objective: The increase in diabetes in Indonesia is largely due to poor food patterns and ingredients. Soybeans as a traditional Indonesian food contain good food ingredients and are believed by the public to prevent damage to pancreatic cells and to maintain the balance of the insulin hormone so as to reduce glucose levels in the blood. This study aims to determine the effect of soy infusion on blood glucose levels (Study on Wistar-strain rats loaded with glucose).
Methods: This study is a True Experiment with using a pretest and posttest design with control group design. The research subjects used in this study were 3 months old male Wistar rats with glucose load intervention 1.35 mg with a concentration of 25%, 50%, 100% for 30 minutes, 60 minutes and 120 minutes.
Results: showed that there were significant differences between groups, p value <0.05. The effectiveness of reducing glucose levels in test animals based on the regression test showed that the best treatment with intervention dose glucose load was 50%, with trend / time of observation y = -1.3251 + 150.3.
Conclusion: This study concluded that the effect of soybean infusion had an effect on decreasing blood glucose levels of the tested animals.
Study of Markers for Assessment of Insulin Resistance in Obese Children and Adolescents
Authors: Shall Sarah Ibrahim El , Hassan Ahmed Mohamed , Mohamed Wesam Salah , Hafez Mona Hasan , Erfan Adel Ali 
Published: March 2021

Background: Valid and reliable methods are essential to assess the presence and the extent of insulin resistance, the associated risk factors and the effect of pharmacological and lifestyle interventions. The aim of this work was to evaluate Homeostatic model assessment of insulin resistance (HOMA-IR) for assessment of insulin resistance among obese children and adolescents.
Methods: This case control study included 40 children and adolescent with ages of 6 to 16 years who were classified into: Group I: 20 obese children and adolescents (body mass index (BMI) > 95th percentile on Egyptian growth curves and Group II: 20 healthy children as a control group of matched age and sex to group 1 and who had normal BMI. All subjects underwent 1) Thorough history taking 2) Full clinical examination 3) Laboratory investigations: Fasting blood glucose, Fasting serum insulin level, HOMA-IR, HbA1c.and OGTT.
Results: There is no significant statistical difference as regard age, height, sex and puberty staging in both groups. The mean for weight, BMI, waist circumference, hip circumference, waist/hip ratio and acanthosis nigricans were found to be significantly higher in patient group. FBG, fasting serum insulin, HbA1c and HOMA-IR were significantly higher in patient group than in control group (p <0.001). HOMA-IR was significantly correlated with HbA1c and OGTT in obese patients (p<0.001*).
Conclusions: HOMA-IR can be used in assessment of insulin resistance among obese children and adolescents.
Quality Assessment and Biological Activity Evaluation of Different Brands of Olive Oil
Authors: A-Elbasit Ishraga Eltayeb M. , Ahmed Amna El Amin Mohammed , Satti Nuha Mohammed Elhassan , Imran Mohd. 
Published: March 2021

Background: The quality of medicinal/food products is directly related to the consumer’s safety. Virgin Olive Oil (VOO) is a widely used oil in Saudi Arabia for cooking, frying, and salad dressing. It is also an ingredient of many pharmaceutical products. Therefore, its regular quality assessment is essential for the consumer’s safety.
Objective: To assess standard quality parameters of the marketed VOO brands in the Rafha City of Saudi Arabia and to perform their antioxidant activity evaluation.
Methodology: The different brands of VOO sold in the Rafha City of Saudi Arabia were collected from two supermarkets and one local shop. The quality of the different brands of the VOO was assessed for their physical appearance, solubility, relative density, refractive index, absorbance, acid value, and peroxide value. The standard procedures provided in the British Pharmacopeia (BP) were used to assess these parameters. The antioxidant activity of the oils was performed by the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method.
Results: The VOO sample test results revealed no significant change in the studied parameter's standard values. The VOO samples presented compliance with the specification of VOO provided in the BP. The VOOs were also free of Sesame oil, which is one of the possible adulterants of the VOO. The antioxidant activity data of the VOO samples (IC50 = 107 to 110 mg oil) also matched with antioxidant activity data of the reference VOO (IC50 = 105 mg oil). The antimicrobial activity of the VOO samples and the reference VOO was also comparable.
Conclusion: The different brands of the marketed VOO comply with the specification of VOO provided in the BP. They were suitable for their intended use/application.
Frequency and Severity of Depression in Cancer Patients Presenting to Tertiary Care Hospital
Authors: Kumar Rakesh , Kumar Haresh , Bai Sarika , Shaheen Azra , Pervez Safdar Ali , Rind Shahabuddin , Ahmer Arslan 
Published: March 2021

Introdution: Cancer and depression, independently, cause massive human suffering worldwide. By the end of 2030 the unipolar major depression disorder could be as the chief source of ailment as estimated by World Health Organization.
Objective: Objective of this study is to detect prevalence the frequency and severity of the depression in cancer patients presenting to tertiary care hospital of Karachi.
Methodology: The current prospective cross-sectional research was performed over a period of six months from August 2020 to January 2021 on 179 patients in the Department of Oncology of Civil Hospital Karachi, after approval of synopsis from CPSP and the ethical committee of Civil Hospital. All patients who fulfilled the inclusion criteria and visited OPD of Civil hospital were selected in the study. Informed consent was taken after explaining the procedure, risks and benefits of the study.Patients were assessed clinically by using ICD-10 criteria and then for validity and reliability, patients were screened for presence of depression and its severity through PHQ-9.Patients scoring higher than 4 was labeled as having depression and PHQ-9 score of 5 to 9, 10 to 14, 15 to 19, 20-27 were labeled mild, moderate, moderately severe and severe depression correspondingly. Observed data was entered in the predesigned Performa was gathered and SPSS version 20.0 was used for data analysis. Mean ± SD of age was 47.75±14.901years. Out of 179 patients 95 (53.1%) were male and 84 (46.9%) were female. 93(52%) cancer patients were depressed while 86(48%) were normal. Patients suffering from mild depression were 3.2%, moderate depression were 54.85%, moderately severe depressed were 19.4%, while 22.6% cancer patients were severely depressed. It is to be concluded that out of 179cancer patients 93(52%) diagnosed to have depression while 86(48%) did not have depression. Based on our study findings, it is suggested that depression commonly presented in cancer patients and there is a need to screen all cancer patients for depressive disorder.
Prevalence of Multidrug Resistant Staphylococcus aureus Isolated from Nasal Cavities of MOUAU Students
Authors: Omaba Onyinyechi J. , Udensi Chukwuma G. , Uwakwe Blessing C. , Amanze Emmanuel K. , Okoh Ifunaya M. 
Published: March 2021

Aim: To determine the prevalence of multidrug-resistant Staphylococcus aureus isolated from nasal cavity of MOUAU students.
Methods: The nasal specimens were evaluated using standard microbiological techniques and methicillin resistance test was checked for all isolates of Staphylococcus species by the disc diffusion method.
Results: A total of Eleven (11) Staphylococcus aureus isolates were obtained from forty (40) nasal samples of MOUAU students i.e. four (4) from female and seven (7) from male. This study also showed that the highest number and percentage of Staphylococcus aureus isolates was observed in the male nasal samples 7(30.4%), while the lowest isolate was recorded in female nasal samples 4(23.5%). About 21(52.5%) of the 40 samples showed no traces of Staphylococcus specie. However, the drug susceptibility profile of bacterial isolate from nasal samples reveals varying percentage of sensitivity and resistance to the antibiotics. From this study, Ofloxacin (5 mcg) and Gentamicin (10 mcg) exhibited high percentage of sensitivity against the Staphylococus isolates at 10(90.9%) each. Cefuroxime (30 mcg) and Ceftazidime (30 mcg) showed high level of resistance against the Staphylococcus aureus isolates at 11(100%). No resistance to Ofloxacin (5 mcg) was noted. This study also revealed that 72.7% of Staphylococcus aureus isolates from the nasal cavity of healthy male and female students of Michael Okpara University of Agriculture, Umudike (MOUAU), showed multiple resistance to the antibiotics used.
Conclusion: This study highlights the need to discourage the misuse of antibiotics and to implement strategies that could help eliminate of nasal carriage of Staphylococcus aureus. This will help to prevent severe Staphylococcus aureus infections in our environments. Also, it was report that Ofloxacin (5 mcg) and Gentamicin (10 mcg) antibiotics could be an alternative choice to use and to control MRSA infection as an effective antibacterial agent.
Asymptotic consensus via switching adaptive for nonlinear multi‐agent systems subject to atypical disturbances
Authors: Yu Linzhen , Liu Yungang 
Published: March 2021

SummaryThe paper is devoted to the asymptotic output consensus for a class of uncertain nonlinear multi‐agent systems. The disturbance that the system suffered is said to be “atypical" since, unlike the related literature, it is unnecessarily continuously differentiable (e.g., sawtooth wave), and even permitted to be discontinuous (e.g., square wave), despite requiring it to be of unknown integer multiples of certain period. Typically, the multi‐agent systems admit more than one ingredient causing heterogeneities: (i) No identical requirement is made on the system nonlinearities and input directions (the unknown signs of the input coefficients). (ii) The orders of agent dynamics can be different (the dynamics are first‐order, second‐order, or even high‐order). Nevertheless, in the context, we still pursue the asymptotic output consensus, and unlike some related literature, instead of seeking a time‐varying strategy which means the introduction of infinitely large gains, we combine a refined switching strategy with continuous adaptive one together to propose a new consensus protocol. It turns out that under the proposed protocol, all the agent outputs reach a common value while all the closed‐loop signals are bounded. Simulation examples are given to demonstrate the effectiveness of the proposed protocol.
Synthesis and Reactivity of Allenylboron Compounds
Authors: Manna Samir , Das Kanak Kanti , Aich Debasis , Panda Santanu 
Published: March 2021

AbstractOrganoboron compounds have found widespread application in everyday organic synthesis. The Lewis acidic properties, non‐toxicity, stability, and easy commercial availability of organoboron compounds have resulted in considerable attention from organic chemists. Over the last several decades, there has been a sizeable development of new organoboron compounds useful in organic synthesis. Allenylboron compounds have emerged as a promising scaffold for various synthetic transformations, including allenylation and propargylation of carbonyl compounds, imines, activated olefins, and others; hydroboration‐allylation with carbonyl/imine, and more. On the other hand, a good number of synthetic methods have evolved over the years to access substituted allenylboron compounds in good yield. This review highlights the methods known to date for the synthesis and reactivity of allenylboron compounds in a chronological manner.magnified image
Biologically normal sleep in the mother‐infant dyad
Authors: Rudzik Alanna E. F. , Ball Helen L. 
Published: March 2021

AbstractObjectivesWe examine infant sleep from evolutionary, historico‐cultural, and statistical/epidemiological perspectives and explore the distinct conceptions of “normal” produced by each. We use data from the “Sleeping Like a Baby” study to illustrate how these perspectives influence the ideals and practices of new parents.MethodsThe “Sleeping Like a Baby” study investigated maternal–infant sleep in north‐east England. Sleep data for exclusively breastfeeding (EBF) and formula‐feeding (EFF) dyads were captured every 2 weeks from 4 to 18 weeks postpartum through actigraphy and maternal report. Mothers also reported their infant sleep ideals and practices. Results explore objective and maternally‐reported infant sleep parameters, and concordance of maternal ideals and practices with public health guidance.ResultsComparison of sleep measures showed that mothers overestimate infant sleep duration compared with actigraphy; EFF mothers' reports were significantly more inaccurate than those of EBF mothers. For infants moved to a separate bedroom, maternally‐reported sleep increases were not borne out by actigraphy. Across the study period, concordance of maternal ideal sleep location with public health recommendations occurred on average for 54% of mothers, while concordance in practice fell from 75% at 4–8 weeks to 67% at 14–18 weeks. Discordance for EBF dyads occurred due to bedsharing, and for EFF dyads due to infants sleeping in a room alone.ConclusionsBeliefs about “normal” infant sleep influence parents' perceptions and practices. Clinical and scientific infant sleep discourses reinforce dominant societal norms and perpetuate these beliefs, but biological and evolutionary views on infant sleep norms are beginning to gain traction with parents and health practitioners.
Cobalamin J disease detected on newborn screening: Novel variant and normal neurodevelopmental course
Authors: Pillai Nishitha R. , Miller Dana , Pierpont Elizabeth I. , Berry Susan A. , Aggarwal Anjali 
Published: March 2021

AbstractCobalamin J disease (CblJ) is an ultra‐rare autosomal recessive disorder of intracellular cobalamin metabolism associated with combined methylmalonic acidemia and homocystinuria. It is caused by pathogenic variants inABCD4, which encodes an ATP‐binding cassette (ABC) transporter that affects the lysosomal release of cobalamin (Cbl) into the cytoplasm. Only six cases ofCblJhave been reported in the literature. Described clinical features include feeding difficulties, failure to thrive, hypotonia, seizures, developmental delay, and hematological abnormalities. Information on clinical outcomes is extremely limited, and no cases of presymptomatic diagnosis have been reported. We describe a now 17‐month‐old male withCblJdetected by newborn screening and confirmed by biochemical, molecular, and complementation studies. With early detection and initiation of treatment, this patient has remained asymptomatic with normal growth parameters and neurodevelopmental function. To the best of our knowledge, this report represents the first asymptomatic and neurotypical patient withCblJ.
Relating Binding Energy and Scattering Length of Weakly Bound Dimers of Strontium
Authors: Augustovičová Lucie D. , Špirko Vladimír 
Published: March 2021

AbstractThe s‐wave scattering length (a) is an important parameter in ultracold collisions and precision tests of fundamental physics, yet its accurate calculation remains a challenge. Solving suitable vibrational Schrödinger equations with scaled interaction potentials and reduced masses, the relationship between the binding energy (D0) of the highest vibrational state and the s‐wave scattering length is derived for a set of ground state Sr2 isotopomers. The resulting “a versus D0” relations are robust even if approximate potentials are used, thus enabling reliable scattering lengths to be determined directly from experimental binding energies. The presented approach will have broad applicability, notably when an accurate potential is unavailable and when the literature (semiclassical) counterparts of the probed “a versus D0” relations become inadequate.
The Metallocene Battery: Ultrafast Electron Transfer Self Exchange Rate Accompanied by a Harmonic Height Breathing
Authors: Beladi‐Mousavi Seyyed Mohsen , Sadaf Shamaila , Hennecke Ann‐Kristin , Klein Jonas , Mahmood Arsalan Mado , Rüttiger Christian , Gallei Markus , Fu Fangyu , Fouquet Eric , Ruiz Jaime , Astruc Didier , Walder Lorenz 
Published: March 2021

AbstractThe first all‐metallocene rechargeable battery consisting of poly‐cobaltocenium/‐ and poly‐ferrocene/reduced graphene oxide composites as anode and cathode was prepared. The intrinsically fast ET self‐exchange rate of metallocenes was successfully combined with an efficient ion‐percolation achieved by molecular self‐assembly. The resulting battery materials show ideal Nernstian behavior, is thickness scalable up to >1.2 C cm−2, and exhibit high coulombic efficiency at ultrafast rates (200 A g−1). Using aqueous LiClO4, the charge is carried exclusively by the anion. The ClO4− intercalation is accompanied by a reciprocal height change of the active layers. Principally, volume changes in organic battery materials during charging/discharging are not desirable and represent a major safety issue. However, here, the individual height changes—due to ion breathing—are reciprocal and thus prohibiting any internal pressure build‐up in the closed‐cell, leading to excellent cycling stability.
Multitarget‐directed therapeutics: (Urea/thiourea)2 derivatives of diverse heterocyclic‐Lys conjugates
Authors: Pavan Kumar H. , Kumara H. K. , Suhas R. , Channe Gowda D. 
Published: March 2021

AbstractThe synthesis of a new small library of molecules containing bis‐urea/thiourea pendants in lysine conjugated to three different heterocycles is described. The heterocycles used in this study have benzisoxazole/piperazine/piperidine units. After a detailed antimicrobial, antioxidant, and anti‐inflammatory evaluation, it was found that the most active compounds are 10, 11, 14, 15, 18, 19 and 10, 11, 19 and 8, 9, 12, 13, 16, 17, respectively. Further, it was observed that the presence of all three entities, that is, urea/thiourea, the substituent (OMe/F), as well as the heterocycle, is highly essential for exerting potent activity. Among the heterocycles, the presence of isoxazole seems to be highly beneficial for exerting good potency. In continuation, docking studies have revealed extraordinary binding efficiency for some of the active compounds. Given their potent biological results and docking score, some of the title compounds could be potential drug candidates for microbial‐related diseases and provide a basis for future research into the development of molecules possessing multitask ability.
Psychometric properties of Structured Clinical Interview for DSM‐5 Disorders‐Clinician Version (SCID‐5‐CV)
Authors: Shabani Amir , Masoumian Samira , Zamirinejad Somayeh , Hejri Maryam , Pirmorad Tahereh , Yaghmaeezadeh Hooman 
Published: March 2021

AbstractObjectivesThe purpose of this study was to evaluate the psychometric properties of Structured Clinical Interview Version for DSM‐5 (R) Clinical Version (SCID‐5‐CV) in a population of patients with psychiatric disorders in Tehran.MethodThe study population included all outpatients and inpatients referred to three psychiatric centers in Tehran, namely Iran Psychiatric Hospital, Rasoul Akram Hospital, and Clinic of Behavioral Sciences and Mental Health (Tehran Psychiatric Institute). Inclusion criteria included age between 16 and 70 years, informed consent to study, ability to understand and speak Persian, and no specific physical problems that interfere with the conduct of the interview. Also, exclusion criteria included inability to communicate, mental retardation or dementia, severe symptoms of acute psychosis, and severe restlessness. In addition to demographic questionnaire, Persian version of SCID‐5‐CV was used in this study. Finally, diagnostic validity, test–retest reliability, and inter‐rater reliability were used to evaluate the information.ResultsIn terms of the kappa criterion, for all diagnoses except for anxiety disorders, kappa was above 0.4 as a result of agreement above average, but in anxiety disorders with kappa 0.34 there was a moderate agreement between psychiatrist and SCID interviewer reports. Also, according to the psychiatrist's diagnosis as the gold standard, in most diagnoses, except for anxiety disorders, kappa was higher than 0.80, indicating the desirable characteristic of this tool in the diagnosis of disorders. Sensitivity of all diagnoses was higher than 0.80.ConclusionAccording to the findings of the present study, SCID‐5‐CV can be used for diagnostic purposes in psychiatric clinics and hospitals and to evaluate the treatment process of patients. In general, this version is suitable especially the schizophrenia spectrum and other psychiatric disorders; however, using SCID‐5‐CV for anxiety‐related disorders should be done with caution.
Self‐Template Construction of High‐Performance Co, N‐Decorated Carbon Nanotubes from a Novel Cobalt Dicyandiamide Molecule
Authors: Li Jingjing , Chen Shuai , Liu Mengmeng , Li Zhihong , Dong Zhengping , Zhang Fengwei , Zhang Xian‐Ming 
Published: March 2021

AbstractN‐doped carbon nanotubes (NCNTs) based composites have shown great prospect in catalysis relevant communities, which are often evolved from commercial CNTs and nitrogenous hybrid precursors. However, the direct fabrication of high‐performance and non‐noble metal uniformly embedded NCNTs from a single molecule level without foreign ions remains a thorny issue. Herein, we firstly report a high surface area and large diameter NCNTs (215.7 m2 g−1, 150 nm) embedded with Co NPs and atomically dispersed CoNx active sites via a facile and self‐template pyrolysis of a novel synthesized cobalt dicyanamide molecule. The resulting Co@NCNTs‐800 catalyst exhibits superior catalytic activity toward nitrobenzene hydrogenation compared to the catalyst prepared from a mixture of dicyandiamide and CoCl2 under mild conditions (>99 % vs. 1.3 % conversion). Furthermore, it also presents a prominent activity and selectivity for the hydrogenation of various nitroaromatics, and possesses the best catalytic performance compared to the existing non‐noble metal‐based heterogeneous catalytic systems.