bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examining the effects of robots' physical appearance, warmth, and competence in frontline services: The Humanness‐Value‐Loyalty model
Authors: Belanche Daniel , Casaló Luis V. , Schepers Jeroen , Flavián Carlos 
Published: November 2021

AbstractBecause of continuous improvements in their underlying technologies, customers perceive frontline robots as social actors with a high level of humanness, both in appearance and behavior. Advancing from mere theoretical contributions to this study field, this article proposes and empirically validates the humanness‐value‐loyalty model (HVL model). This study analyzes to what extent robots' perceived physical human‐likeness, perceived competence, and perceived warmth affect customers' service value expectations and, subsequently, their loyalty intentions. Following two pretests to select the most suitable robots and ensure scenario realism, data were collected by means of a vignette experimental study and analyzed using the partial least squares method. The results reveal that human‐likeness positively affects four dimensions of service value expectations. Perceived competence of the robot influences mainly utilitarian expectations (i.e., functional and monetary value), while perceived warmth influences relational expectations (i.e., emotional value). Interestingly, and contrary to theoretical predictions, the influence of the robot's warmth on service value expectations is more pronounced for customers with a lower need for social interaction. In sum, this study contributes to a better understanding of customers' reactions to artificial intelligence‐enabled technologies with humanized cognitive capabilities and also suggests interesting research avenues to advance on this emerging field.
Association of tumor mutational burden with genomic alterations in Chinese urothelial carcinoma
Authors: Chen Xusheng , Ou Zhenyu , Wang Lei , Zhang Zhenting , Fan Xiaodong , Liu Huanhuan , Wang Wenping , Zhang Yanrui , Zhu Jun , Liang Xiayuan , Lou Feng , Cao Shanbo , Yao Ye , Wang Huina , Yao Xin 
Published: November 2021

AbstractThe tumor mutational burden (TMB) calculated by whole‐exome sequencing (WES) is a promising biomarker for the response to immune checkpoint inhibition (ICIs) in solid tumors. However, WES is not feasible in the routine clinical setting. In addition, the characteristics of the TMB in Chinese urothelial carcinoma (UC) are unclear. The aim of this study was to demonstrate the reliability of an Acornmed 808 panel and analyze the characteristics of the TMB in Chinese UC. An Acornmed 808 panel was designed and virtually validated using UC data from the cancer genome atlas (TCGA). Comprehensive analysis of sequencing and clinical data was performed to explore the characteristics of the TMB for 143 Chinese UC patients. Compared to the TMB calculated with random 808‐, 500‐, and 250‐gene panels, the TMB calculated with the Acornmed 808 panel was closer to that calculated by WES. There were marked disparities in the mutational landscape and TMB between Chinese and TCGA UC data. The TMB was negatively associated with copy number variation (CNV). In contrast, the TMB was positive correlation with numbers of mutated DDR genes. Exposure to aristolochic acid signature was observed only in the TMB‐high groups. The Acornmed 808 panel is a clinically practical method to assess the TMB. The TMB was associated with the DDR gene status and CNV counts and might be a biomarker for further stratification of UC patients. The study suggested that patients with high TMB may have a unique carcinogenic mechanism.
Harnessing the power of the electronic health record for ALS research and quality improvement: CReATe CAPTURE‐ALS and the ALS Toolkit
Authors: Granit Volkan , Grignon Anne‐Laure , Wuu Joanne , Katz Jonathan , Walk David , Hussain Sumaira , Hernandez Jessica , Jackson Carlayne , Caress James , Yosick Tom , Smider Nancy , Benatar Michael 
Published: November 2021

AbstractThe electronic health record (EHR) is designed principally to support the provision and documentation of clinical care, as well as billing and insurance claims. Broad implementation of the EHR, however, also yields an opportunity to use EHR data for other purposes, including research and quality improvement. Indeed, effective use of clinical data for research purposes has been a long‐standing goal of physicians who provide care for patients with ALS, but the quality and completeness of clinical data, as well as the burden of double data entry into the EHR and into a research database, have been persistent barriers. These factors provided motivation for the development of the ALS Toolkit, a set of interactive digital forms within the EHR that enable easy, consistent, and structured capture of information relevant to ALS patient care (as well as research and quality improvement) during clinical encounters. Routine use of the ALS Toolkit within the context of the CReATe Consortium's institutional review board–approved Clinical Procedures to Support Research in ALS (CAPTURE‐ALS) study protocol, permits aggregation of structured ALS patient data, with the goals of empowering research and driving quality improvement. Widespread use of the ALS Toolkit through the CAPTURE‐ALS protocol will help to ensure that ALS clinics become a driving force for collecting and aggregating clinical data in a way that reflects the true diversity of the populations affected by this disease, rather than the restricted subset of patients that currently participate in dedicated research studies.
Machine‐learning‐enabled discrete element method: Contact detection and resolution of irregular‐shaped particles
Authors: Lai Zhengshou , Chen Qiushi , Huang Linchong 
Published: November 2021

AbstractThis paper presents a machine learning (ML)‐enabled discrete element method (DEM) for the computational mechanics of irregular‐shaped particles. ML‐enabled DEM, as with most conventional DEMs, encompasses four main steps in one typical calculation cycle, namely, (1) the detection and resolution of contacts, (2) the evaluation of contact behavior, (3) the calculation of particle motion, and (4) the updating of particle geometric descriptions. Unlike conventional DEMs, the proposed method constructs and employs neural networks to detect particle contacts and resolve contact geometric features. Neural networks take particle geometric descriptors as inputs and output the contact status and contact geometric features. Using two‐dimensional elliptical particles as an example, the performance of the ML‐enabled DEM is investigated through five numerical experiments and compared with analytical solutions or conventional DEM methods. A sixth numerical experiment involving irregular‐shaped particles is also presented to showcase the potential and applicability of the proposed method for other particle shapes. ML‐enabled DEM can accurately capture the trajectory and energy evolution of individual particles, the fabric characteristics of dense packing, and the mechanical behavior of packing under large loads, while demonstrating computational efficiency over conventional methods.
Fabrication of fire‐response functional separators with microcapsule fire extinguishing agent for lithium‐ion battery safety
Authors: Lou Ping , Zhang Weixin , Han Qigao , Tang Shun , Tian Jie , Li Yan , Wu Hao , Zhong Yunhui , Cao Yuan‐Cheng , Cheng Shijie 
Published: November 2021

AbstractFire safety issues hinder the large‐scale application of lithium‐ion batteries (LiBs). Here, a new type of fire‐response separators is prepared by loading the microcapsule fire extinguishing agent on the surface of the separator. The shell of the microcapsule will break automatically at a certain temperature and release the fire extinguishing agent when thermal runaway of LiBs occurs, which can quickly absorb heat through endothermic reaction and ensure LiBs will not burn or explode. The porosity of fire‐response separator is 53.6%, the electrolyte uptake is 132% and the ionic conductivity is 1.00 mS cm‐1. The initial specific capacity is 2643 mAh g‐1 at 4°C and the capacity retention rate is 93% after 200 cycles for NCM523 battery based fire‐response separator. The temperature of LiBs based on the fire‐response separator can automatically drop to room temperature in 20 seconds, which ensures the safety of other adjacent LiBs. This work proposes a new active protection concept to solve the safety problem of LiBs.
Minimum k‐cores and the k‐core polytope
Authors: Mikesell Derek , Hicks Illya V. 
Published: November 2021

AbstractThe minimum k‐core problem asks for the smallest induced subgraph of minimum degree k. It has been shown that this problem is NP‐hard, and thus sophisticated techniques are required to obtain good solutions and approximations. In this article, the minimum k‐core problem is modeled as a binary integer program and relaxed as a linear program. Since the relaxation may yield a non‐integral solution, a branch‐and‐cut framework is used to find an integral optimal solution. It is shown that the edge and cycle transversals of the graph give valid inequalities for the convex hull of the k‐core polytope—which can be further generalized to a family of ‐core transversals. Further, a heuristic for the transversal of the minimal ‐cores is given with its associated valid inequality. Additionally, improved valid inequalities are generated using bounds involving the girth of the graph. Multiple heuristics are explored for finding initial bounds for the branching process utilizing the degree distribution of the graph. Finally, numerical results are given comparing the branch‐and‐bound, branch‐and‐cut, and heuristic techniques.
An integrative review of nursing leadership in Saudi Arabia
Authors: Alilyyani Bayan , Kerr Michael S. , Wong Carol , Wazqar Dhuha Y. 
Published: November 2021

AbstractAimsThe aims of this integrative review were to describe leadership styles from the nursing literature in Saudi Arabia and to identify the current state of evidence about relationships between leadership styles and nurse, patient and organization outcomes in Saudi Arabia.DesignIntegrative review was used as a design for this study.MethodsThe following search terms were used with databases: ‘Saudi Arabia’, ‘leadership theory*’, ‘leadership style*’, ‘leadership model*’, ‘management style’ and ‘nurse*’. Methodological quality was assessed using two different quality rating tools for quantitative and qualitative studies. Databases used for this review included Nursing & Allied Health Database, Cochrane Database of Systematic Reviews, PubMed, CINAHL, Embase, PsycINFO, Scopus, Web of Science and ProQuest Dissertations & Theses.ResultsNine manuscripts representing eight studies were included in this review. The papers reviewed included quantitative (n = 6), qualitative (n = 2) and mixed methods studies (n = 1). Results were grouped into different themes, identified as nursing leadership styles in Saudi Arabia, leadership styles and nurses' outcomes, and demographics and leadership styles.
Introduction of sugarcane in Al‐Andalus (Medieval Spain) and its impact on children's dental health
Authors: Jiménez‐Brobeil Sylvia A. , Maroto Rosa M. , Milella Marco , Laffranchi Zita , Reyes Botella Candela 
Published: November 2021

AbstractThe introduction of sugarcane in Europe by the Arabs in the 10th century AD brought about a drastic change in gastronomy and oral health. In Southern Spain (Al‐Andalus), sugarcane was mainly consumed by the elite, although its consumption became relatively widespread during the Nasrid Kingdom. The aim of this study was to explore the effect of the introduction of sugar on human diet and oral health by comparing patterns of caries in deciduous teeth between nonadult skeletal samples from two Nasrid populations (La Torrecilla and Talará) and a comparative set representing various Iberian populations without access to sugarcane (from Bronze to Medieval Ages). We analyzed 770 teeth from 115 nonadults divided into three groups: infants under 2 years of age, nonadults presenting only deciduous teeth, and nonadults presenting mixed deciduous and permanent dentition. The frequency of caries is high in the Nasrid individuals and very low in the comparative sample. This finding is in agreement with contemporaneous written sources on the utilization of sugarcane in the diet and as a pacifier for infants during weaning. Differences in the frequency of caries between the Nasrid samples (higher in Talará) are likely related to the socioeconomic differences between these populations.
Manifestation of the silicate filler additives and electron beam irradiation on properties of SBR/devulcanized waste tire rubber composites for floor tiles applications
Authors: El‐Nemr Khaled F. , Ali Magdy A. , Gad Yasser H. 
Published: November 2021

AbstractVirgin styrene‐butadiene rubber (SBR) was replaced by devulcanized waste tire rubber (DWR) 50/50 and used as a rubber base for preparing composites to depend on different silicate types at fixed content 40 phr (part per hundred part of rubber). All composites were mixed on a rubber roll mill and then subjected to electron beam irradiation to induce cross‐linking at a dose of 100 kGy. Different silicate fillers were used in this study such as precipitated silica (PS) 40 phr, waste glass window (WG) – PS 20/20 phr, fly ash (FA)‐PS 20/20 phr, and micaosilica (MS)‐PS 20/20 phr. Waste silicate was treated with (3‐aminopropyl) trimethoxysilane (APTMS) and blended with PS. Mechanical properties were measured for the composites like ultimate tensile strength, elongation at break, tensile modulus, and the cross‐link density was calculated from the mechanical study. As well as, application for floor tiles included compression set and abrasion resistance measurements. All results indicated an enhancement in ultimate tensile strength, modulus, and cross‐link density by adding silicate fillers and more enhanced in the electron beam irradiated samples. For the application of floor tiles, the MS filler gave a good compression set and abrasion resistance followed by other silicate fillers (PS, FA), except WG.
Development of an MPLC‐based laser head
Authors: Bayol Julien 
Published: November 2021

AbstractBeam shaping has already often demonstrated its benefits when applied to laser material processing. It is used in laser beam welding to optimize the energy input on the part and then improve quality and yield. A laser head using multi‐plane light conversion (MPLC) beam shaping technology has been developed, dedicated to steel welding. The performance of this laser head paves the way for the development of new welding techniques such as laser‐arc hybrid welding, or on materials such as copper.
Chronic feelings of emptiness in a large undergraduate sample: Starting to fill the void
Authors: Martin Jacob A. , Levy Kenneth N. 
Published: November 2021

AbstractChronic emptiness in borderline personality disorder (BPD) has received little empirical attention. We sought to examine basic properties of a single chronic emptiness item, including prevalence, reliability, validity, the relation of the emptiness item to other BPD criteria, and measures of personality. Undergraduates enrolled in psychology courses over 12 years' time completed the McLean Screening Instrument for Borderline Personality Disorder (MSI‐BPD) (N = 22,217). Subsets of participants completed the International Personality Disorder Examination—Screening Questionnaire (IPDE‐SQ) (N = 2732), The Revised NEO Personality Inventory (Anxiety, Angry Hostility, Depression, Positive Emotions [reversed], and Impulsivity facets) (N = 10,506), and the Depression Anxiety Stress Scales (DASS) (N = 1110) as validity indicators; 10.0% of respondents endorsed emptiness. Reliability indices suggested moderate levels of reliability between two emptiness items (r(2730) = 0.61, p < 0.001). Among BPD criteria, emptiness and identity disturbance correlated most strongly (r(22,215) = 0.81, p < 0.001). MSI emptiness was more correlated with depression on the NEO (r(10,504) = 0.43, p < 0.001) and DASS (r(1108) = 0.51, p < 0.001) than other facets of negative affect. Emptiness was more correlated with greater borderline pathology than any other MSI‐BPD item (Sample 1, rtet = 0.87; Sample 2, rtet = 0.86). This criterion warrants further study and attention, especially related to assessment of BPD.
Helicoverpa armigeraandHelicoverpa zeahybridization: constraints, heterosis, and implications for pest management
Authors: Rios Danielly AM , Specht Alexandre , Roque‐Specht Vânia F , Sosa‐Gómez Daniel R , Fochezato Júlia , Malaquias Juaci V , Gonçalves Gislene L , Moreira Gilson RP 
Published: November 2021

AbstractBACKGROUNDThe invasion ofHelicoverpa armigera(Hübner) (Lepidoptera: Noctuidae) into the New World has made it possible for this pest to hybridize with a native American species,H. zea(Boddie), under natural conditions. We investigated the viability and development of hybrids of these twoHelicoverpaspecies. We reared the parental species and evaluated crosses betweenH. armigeramales andH. zeafemales andvice versa, two intercrosses between hybrids, and eight backcrosses between hybrids and parental species. We estimated the length of immature stages, fecundity, survival, sex ratio, and heterosis.RESULTSAlthough hybridization occcurred, with heterosis during the development of immatures, reproductive incompatibilities also were observed between the parental species and between hybrids from subsequent crosses. The interspecific crosses between hybrids and backcrosses confirmed the possibility of introgression events and their perpetuation in field populations. The results indicate that hybridization events are favored at high population levels, while at low population levels the ‘species identities’ will be maintained.CONCLUSIONSThe possibility of interspecific gene flow and its perpetuation through successive crosses and backcrosses suggests several recommenations for management. Populations of both species should be maintained at an equilibrium level to reduce the chance of interspecific crosses, which are presumably more likely to occur during pest outbreaks. The existence of hybridization and resistance to different active pesticide ingredients should be monitored. All practices related to managing the resistance of these pests to chemical and biological insecticides should be systematized to reduce the chance of selecting for resistant individuals.
Physiologically based pharmacokinetic modeling for dose optimization of quinine–phenobarbital coadministration in patients with cerebral malaria
Authors: Sae‐heng Teerachat , Rajoli Rajith Kumar Reddy , Siccardi Marco , Karbwang Juntra , Na‐Bangchang Kesara 
Published: November 2021

AbstractPatients with cerebral malaria with polymorphic Cytochrome P450 2C19 (CYP2C19) genotypes who receive concurrent treatment with quinine are at risk of inadequate or toxic therapeutic drug concentrations due to metabolic drug interactions. The study aimed to predict the potential dose regimens of quinine when coadministered with phenobarbital in adult patients with cerebral malaria and complications (e.g., lactic acidosis and acute renal failure) and concurrent with seizures and acute renal failure who carry wild‐type and polymorphic CYP2C19. The whole‐body physiologically based pharmacokinetic (PBPK) models for quinine, phenobarbital, and quinine–phenobarbital coadministration were constructed based on the previously published information using Simbiology®. Four published articles were used for model validation. A total of 100 virtual patients were simulated based on the 14‐day and 3‐day courses of treatment. using the drug–drug interaction approach. The predicted results were within 15% of the observed values. Standard phenobarbital dose, when administered with quinine, is suitable for all groups with single or continuous seizures regardless of CYP2C19 genotype, renal failure, and lactic acidosis. Dose adjustment based on area under the curve ratio provided inappropriate quinine concentrations. The recommended dose of quinine when coadministered with phenobarbital based on the PBPK model for all groups is a loading dose of 2000 mg intravenous (i.v.) infusion rate 250 mg/h followed by 1200 mg i.v. rate 150 mg/h. The developed PBPK models are credible for further simulations. Because the predicted quinine doses in all groups were similar regardless of the CYP2C19 genotype, genotyping may not be required.
A QFT approach to robust dual‐rate control systems
Authors: Baños Alfonso , Salt Julián , Casanova Vicente 
Published: November 2021

AbstractA dual‐rate control system is a hybrid system composed of continuous‐time and discrete‐time elements with two sampling frequencies. In this work, a new frequency domain analysis and design approach, based on the quantitative feedback theory is developed, to cope with robust stability and robust tracking specifications. Tracking specifications are considered not only in the discrete‐time but also in continuous‐time, that allow a precise description of the intersample behavior (ripples), and characterization of frequencies below and beyond the Nyquist frequencies. Several illustrative examples and a case study has been developed.
A novel act‐and‐wait control scheme for fixed‐time stabilization of input‐delay systems and assignment of the monodromy matrix
Authors: Zhang Zhe , Zhou Bin , Michiels Wim , Yang Xuefei 
Published: November 2021

AbstractAn act‐and‐wait (AAW) fashioned control scheme is proposed for input delay systems, which is characterized by switches between different gains during the acting phases. Under very mild conditions, the novel control scheme allows to freely assign the monodromy matrix and to solve the fixed‐time stabilization problem. In additionally, a variant is proposed where the control law is simplified by keeping the control signal constant after every switch, amendable for a sampled‐data implementation. For multi‐input systems it is also demonstrated how the number of switches per acting period in the basis scheme can be reduced to the dimension of the system, starting from the controllability indices set. The effectiveness of the proposed methods is verified on two simulation case‐studies.
A simple low‐cost approach for transport parameter determination in mountain rivers
Authors: Castillo Daniela , Runkel Robert L. , Duhalde Denisse , Pastén Pablo , Arumí José L. , Oyarzún Jorge , Núñez Jorge , Maturana Hugo , Oyarzún Ricardo 
Published: November 2021

AbstractA simplified low‐cost approach to experimentally determine transport parameters in mountain rivers is described, with an emphasis on the longitudinal dispersion coefficient (DL). The approach is based on a slug injection of table salt (NaCl) as a tracer and specific conductance readings at different locations downstream of the injection spot. Observed specific conductance readings are fit using the advection‐dispersion equation with OTIS‐P, yielding estimates of cross‐sectional area and longitudinal dispersion coefficient for various stream reaches. Estimates of the DL are used to assess the accuracy of several empirical equations reported in the literature. This allowed the determination of complementary transport parameters related to transient storage zones. The empirical equations yielded rather high DL values, with some reaching up an order of magnitude higher to those obtained from tracer additions and OTIS‐P. Overall, the proposed approach seems reliable and pertinent for river reaches of ca. 150 m in length.