bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the Antecedents of Iranian College Students’ Residential Satisfaction using Structural Equation Modeling
Authors: Nazarpour Mohammad‐Taghi , Norouzian‐Maleki Saeid 
Published: December 2021

By living far away from the family, college students lose social support from their families, and therefore, they may feel loneliness, and lack of attachment to the new environment. The main objective of this study was to investigate the factors affecting residential satisfaction (RS) of students living in dormitories. A survey was developed and distributed to 850 students of the dormitory of Shahid Beheshti University in Tehran, Iran. After the data had been cleaned, the statistical analyses were conducted on 622 residents of the dormitory. Confirmatory factor analysis (CFA) and structural equation modeling (SEM) were utilized to capture the complex relationships among related constructs. The results revealed that the main factors that influenced RS were social relations and nature relatedness. The results confirmed the positive and significant effect of controllability and security on RS.
Modelling the impacts of climate change on skipjack tuna (Katsuwonus pelamis) in the Mozambique Channel
Authors: Nataniel Anildo , Pennino Maria Grazia , Lopez Jon , Soto Maria 
Published: December 2021

AbstractSkipjack tuna play a significant role in global marine fisheries and are of particular interest for socio‐economy in the tropical waters of the Mozambique Channel. However, human‐induced climate change has been leading to a reduction and reallocation of biomass, along with other ecological changes, thereby creating a feedback loop with negative socio‐economic consequences for fisheries‐reliant coastal communities. The objective of this study was to predict the potential skipjack tuna fishing grounds by 2050 and 2100. To that end, skipjack tuna catch data were collected from Spanish purse seine fleets, and subsequently, generalized additive models were used to model these data against a combination of environmental variables and future pathway projections from BIO‐ORACLE models under optimistic (RCP2.6) and pessimistic (RCP8.5) scenarios. Both optimistic and pessimistic scenarios by 2050 predicted that the potential fishing grounds will relocate southward from tropical to more temperate waters, with moderate shifts in the potential fishing grounds of purse seines to the latitude >16°S, whereas the pessimistic scenario predicted higher displacement catches of purse seines in the southernmost part (>24°S) and moderate to high catches in northern (>20°S) of the Mozambique Channel by the end of the century. Despite the degree of uncertainty surrounding the climate change impacts on skipjack tuna, we argue that fisheries stakeholders, administrators and regional tuna fisheries management organizations should work towards building resilience and ensuring sustainability while reducing or mitigating vulnerability and climate change impacts on local and regional communities and their livelihoods.
Visual statistical learning in infancy: Discrimination of fine‐grained regularities depends on early test trials
Authors: Bertels Julie , San Anton Estibaliz , Boursain Emeline , Bulf Hermann , Destrebecqz Arnaud 
Published: December 2021

AbstractInfants’ ability to detect statistical regularities between visual objects has been demonstrated in previous studies (e.g., Kirkham et al., Cognition, 83, 2002, B35). The extent to which infants extract and learn the actual values of the transitional probabilities (TPs) between these objects nevertheless remains an open question. In three experiments providing identical learning conditions but contrasting different types of sequences at test, we examined 8‐month‐old infants’ ability to discriminate between familiar sequences involving high or low values of TPs, and new sequences that involved null TPs. Results showed that infants discriminate between these three types of sequences, supporting the existence of a statistical learning mechanism by which infants extract fine‐grained statistical information from a stream of visual stimuli. Interestingly, the expression of this statistical knowledge varied between experiments and specifically depended on the nature of the first two test trials. We argue that the predictability of this early test arrangement—namely whether the first two test items were either predictable or unexpected based on the habituation phase—determined infants’ looking behaviors.
A systematic review ofeye‐tracking‐basedresearch on animated multimedia learning
Authors: Coskun Atakan , Cagiltay Kursat 
Published: December 2021

AbstractBackgroundThe most challenging task in eye‐tracking‐based multimedia research is to establish a relationship between eye‐tracking metrics (or cognitive processes) and learners' performance scores. Additionally, there are current debates about the effectiveness of animations (or simulations) in promoting learning in multimedia settings.ObjectivesAs a result, the current study aimed to review eye tracking‐based research on learners' cognitive processes in the animated/simulated multimedia learning domain.MethodFor this purpose, fifty‐seven (57) studies were systematically determined based on PRISMA guidelines, and they were synthesized.Results and ConclusionsThe notable findings are that (1) most of the reviewed studies have tried to relate eye‐tracking measures to at least one cognitive process (e.g., selecting, organizing, and integrating) which are assumed to take place during multimedia learning; (2) eye‐tracking measurements show whether design features of animation are successful in directing learners' attention; (3) the success of animation in attention‐guiding to the relevant parts may not have a positive impact on learning because individual differences (e.g., prior knowledge, spatial ability, or working capacity) and animation content are the other factors that directly affect the effectiveness of animation over learning.ImplicationsThe current study implies that (i) use of signaling cues in animated multimedia settings diminish visual search and promote higher learning scores, (ii) giving users control over animations causes negative outcomes (e.g., missing micro or macro events); (iii) research on animated multimedia learning should be replicated with the participant group from K‐12, special education (e.g., autistic children), and elders.
LncRNA SNHG1 modulates adipogenic differentiation of BMSCs by promoting DNMT1 mediated Opg hypermethylation via interacting with PTBP1
Authors: Yu Xiao , Song Meng‐Sheng , Rong Peng‐Ze , Chen Xian‐Jun , Shi Lin , Wang Cheng‐Hao , Pang Qing‐Jiang 
Published: December 2021

AbstractRecent evidence indicates that the abnormal differentiation of bone marrow‐derived mesenchymal stem cells (BMSCs) plays a pivotal role in the pathogenesis of osteoporosis. LncRNA SNHG1 has been found to be associated with the differentiation ability of BMSCs. In this study, we aimed to elucidate the role of lncRNA SNHG1 and its associated pathway on the differentiation of BMSCs in osteoporosis. Mice that underwent bilateral ovariectomy (OVX) were used as models of osteoporosis. Induced osteogenic or adipogenic differentiation was performed in mouse BMSCs. Compared to sham animals, lncRNA SNHG1 expression was upregulated in OVX mice. Also, the in vitro expression of SNHG1 was increased in adipogenic BMSCs but decreased in osteogenic BMSCs. Moreover, overexpression of SNHG1 enhanced the adipogenic capacity of BMSCs but inhibited their osteogenic capacity as determined by oil red O, alizarin red, and alkaline phosphatase staining, while silencing of SNHG1 led to the opposite results. LncRNA SNHG1 interacting with the RNA‐binding polypyrimidine tract‐binding protein 1 (PTBP1) promoted osteoprotegerin (Opg) methylation and suppressed Opg expression via mediating DNA methyltransferase (DNMT) 1. Furthermore, Opg was showed to regulate BMSC differentiation. Knockdown of SNHG1 decreased the expressions of adipogenic related genes but increased that of osteogenic related genes. However, the knockdown of Opg partially reversed those effects. In summary, lncRNA SNHG1 upregulated the expression of DNMT1 via interacting with PTBP1, resulting in Opg hypermethylation and decreased Opg expression, which in turn enhanced BMSC adipogenic differentiation and contributed to osteoporosis.
Efficacy of tooth splinting and occlusal adjustment in patients with periodontitis exhibiting masticatory dysfunction: A systematic review
Authors: Dommisch Henrik , Walter Clemens , Difloe‐Geisert Julia C. , Gintaute Aiste , Jepsen Søren , Zitzmann Nicola U. 
Published: December 2021

AbstractObjectiveTo evaluate the efficacy of tooth splinting (TS) and occlusal adjustment (OA) compared to no TS or OA in patients with periodontitis exhibiting masticatory dysfunction.MaterialThe primary outcome criterion was tooth loss (TL), and the secondary outcome parameters were change in probing pocket depth (PPD), change in clinical attachment level (CAL), tooth mobility (TM), and patient‐reported outcome measures (PROMs). Literature search was performed on three electronic databases (from 01/1965 to 04/2021) and focused on clinical studies with at least 12 months follow‐up.ResultsFrom a total of 1515 publications, 51 articles were identified for full‐text reading, of which 2 retrospective case series on TS with low risk of bias and 1 randomized and 2 prospective studies on OA with unclear risk of bias were included. For TS, synthesis of data showed that in 72 patients, 26 out of 311 teeth (weighted mean incidence of TL 8.4%) and 156 out of 1541 teeth with no TS (weighted mean incidence of TL 10.1%) were lost over 2 years following non‐surgical periodontal therapy. The randomized controlled clinical trial (RCT) indicated CAL gain for teeth with OA compared to no OA. For the effect of OA on TL, PPD, and TM, heterogeneous data were retrieved from the included studies.ConclusionsWithin the limitations of this review and based on a low level of evidence, it is concluded that TS does not improve survival of mobile teeth in patients with advanced periodontitis. OA on teeth with mobility and/or premature contacts may lead to improved CAL, while the effect of OA on the remaining periodontal parameters remains unclear.
Complete response of advanced cutaneous squamous cell and basal cell carcinomas with sequential cemiplimab and sonidegib therapy
Authors: Weis J. , Grote C. , Weichenthal M. , Hauschild A. 
Published: December 2021

AbstractA 78‐year‐old woman was referred to our skin cancer centre with three previous incomplete resections in the left cavum conchae of a deep‐infiltrating locally advanced, but still asymptomatic basal cell carcinoma (BCC). The patient noted furthermore two rapidly growing exophytic lesions in the left preauricular and cervical area in the last weeks. The clinical and histological distinction of locally advanced from metastatic cutaneous squamous cell carcinoma (CSCC) lesions was challenging. Imaging analysis with CT scans showed, however, an involvement of the parotid gland as well as multiple small lymph node metastases. The interdisciplinary tumour board decision at our institution recommended a systemic treatment with the PD1‐antibody cemiplimab. After 13 cycles with cemiplimab at a dose of 350 mg intravenously every 3‐weeks, the patient showed a complete response of the two CSCC lesions with histological confirmation. However, the BCC of the left ear appeared to be unchanged and still asymptomatic. The interdisciplinary tumour board considered this tumour to be no candidate for a curative resection or irradiation. Therefore, the patient was exposed to the hedgehog inhibitor sonidegib with a conventional dose of 200 mg orally per day. After 3 months of treatment, the tumour showed a markable regression and a complete response was confirmed by 3‐punch biopsies from this preoperated lesion. Both cemiplimab and sonidegib were excellently tolerated with almost no adverse events apart from a mild fatigue (CTC grade 1) over the first 3 weeks of the cemiplimab therapy. There were no laboratory abnormalities found.
Management of partial and non‐responding cutaneous squamous cell carcinoma
Authors: Jansen P. , Lodde G.C. , Griewank K.G. , Hadaschik E. , Roesch A. , Ugurel S. , Zimmer L. , Livingstone E. , Schadendorf D. 
Published: December 2021

AbstractCutaneous squamous cell carcinoma (cSCC) and basal cell carcinoma are the most common types of skin cancer. For patients with locally advanced and metastatic cSCC, the programmed cell death 1 (PD‐1) inhibitor cemiplimab is approved for systemic treatment. Despite this revolutionary immunomodulatory therapeutic approach, tumours may fail to respond either completely or partially. In addition to the previously established local treatment with radiotherapy or systemic treatment with chemotherapy and epidermal growth factor receptor inhibitors, ongoing trials are currently focussed on re‐stimulating the antitumour immune response in patients with advanced cSCC refractory to PD‐1 inhibitors. In this review, ongoing and recently finished trials with different therapeutic approaches will be discussed.
Evolution of antagonistic and mutualistic traits in the yucca‐yucca moth obligate pollination mutualism
Authors: Althoff David M. , Segraves Kari A. 
Published: December 2021

AbstractSpecies interactions shape the evolution of traits, life histories and the pattern of speciation. What is less clear is whether certain types of species interaction are more or less likely to lead to phenotypic divergence among species. We used the brood pollination mutualism between yuccas and yucca moths to test how mutualistic (pollination) and antagonistic (oviposition) traits differ in the propensity to increase phenotypic divergence among pollinator moths. We measured traits of the tentacular mouthparts, structures used by females to actively pollinate flowers, as well as ovipositor traits to examine differences in the rate of evolution of these two suites of traits among pollinator species. Morphological analyses revealed two distinct groups of moths based on ovipositor morphology, but no such groupings were identified for tentacle morphology, even for moths that pollinated distantly related yuccas. In addition, ovipositor traits evolved at significantly faster rates than tentacular traits. These results support theoretical work suggesting that antagonism is more likely than mutualism to lead to phenotypic divergence.
Novel evolution of a hyper‐elongated tongue in a Cretaceous enantiornithine from China and the evolution of the hyolingual apparatus and feeding in birds
Authors: Li Zhiheng , Wang Min , Stidham Thomas A. , Zhou Zhonghe , Clarke Julia 
Published: December 2021

AbstractThe globally distributed extinct clade Enantiornithes comprises the most diverse early radiation of birds in the Mesozoic with species exhibiting a wide range of body sizes, morphologies, and ecologies. The fossil of a new enantiornithine bird, Brevirostruavis macrohyoideus gen. et sp. nov., from the Lower Cretaceous Jiufotang Formation in Liaoning Province, northeastern China, preserves a few important skeletal features previously unknown among early stem and extant birds, including an extremely elongate bony hyoid element (only slightly shorter than the skull), combined with a short cranial rostrum. The long hyoid provides direct evidence for the evolution of specialized feeding in this extinct species, and appears similar to the highly mobile tongue that is mobilized by the paired epibranchials present in living hummingbirds, honeyeaters, and woodpeckers. The likely linkage between food acquisition and tongue protrusion might have been a key factor in the independent evolution of particularly elongate hyobranchials in early birds.
Asset returns, news topics, and media effects*
Authors: Larsen Vegard Høghaug , Thorsrud Leif Anders 
Published: December 2021

AbstractWe decompose the textual data in a daily Norwegian business newspaper into news topics, and we investigate their predictive and causal role for asset prices. Our findings suggest that news published through the mass media has significant, persistent, and potentially economically profitable predictive power for returns. Moreover, during an exogenous media strike, returns for firms particularly exposed to our news measure experience a substantial fall relative to the control group. Together, these findings lend support for a view where the mass media acts as an “information intermediary” between agents and the state of the world, and disseminates fundamental information to investors.
Affective states and nonsuicidal self‐injury (NSSI): Results from an ecological momentary assessment study of veterans with NSSI disorder
Authors: Dillon Kirsten H. , Glenn Jeffrey J. , Dennis Paul A. , Mann Adam J. , Deming Charlene A. , Aho Natalie , Hertzberg Jeffrey S. , DeBeer Bryann B. , Meyer Eric C. , Morissette Sandra B. , Gratz Kim L. , Silvia Paul J. , Calhoun Patrick S. , Beckham Jean C. , Kimbrel Nathan A. 
Published: December 2021

AbstractBackgroundThe affective states most strongly associated with nonsuicidal self‐injury (NSSI) remain poorly understood, particularly among veterans. This study used ecological momentary assessment (EMA) to examine relationships between affect ratings and NSSI urges and behaviors among veterans with NSSI disorder.MethodsParticipants (N = 40) completed EMA entries via mobile phone for 28 days (3722 total entries). Entries included intensity ratings for five basic affective states, as well as NSSI urges and behaviors, during the past 4 hours.ResultsBivariate analyses indicated that each affect variable was significantly associated with both NSSI urges and behaviors. Angry/hostile and sad were most strongly associated with both NSSI urges and behaviors. A multivariate regression revealed that angry/hostile, disgusted with self, and happy (inversely related) were contemporaneously (within the same period) associated with NSSI behaviors, whereas all five basic affective states were contemporaneously associated with NSSI urges. In a lagged model, angry/hostile and sad were associated with subsequent NSSI urges but not behaviors.ConclusionsFindings highlight the relevance of particular affective states to NSSI and the potential utility of targeting anger in treatments for NSSI among veterans. There is a need for future EMA research study to further investigate temporal relationships between these variables.
When people die by suicide: Introducing unacceptable loss thresholds as a potential missing link between suicide readiness states and actively suicidal clinical states
Authors: Capron Daniel W. , Bauer Brian W. , Bryan Craig J. 
Published: December 2021

AbstractIntroductionContemporary models of suicide have largely overlooked why a person at high risk for suicide attempts suicide at a specific time. We propose the construct of unacceptable loss thresholds (i.e., a person’s tolerance limit for a negative life event, which if violated results in an increase in suicide risk), which addresses many paradoxes in the literature related to suicide triggers. The aim of this paper is to provide preliminary proof of concept and to stimulate replication and further empirical study.MethodsWe recruited an online community sample of individuals with a suicide attempt history (n = 144). These individuals answered questions about the time leading up to their most recent suicide attempt.ResultsThe majority (70.8% yes; 18.1% cannot remember; 11.1% no) reported creating a threshold of unacceptable loss, and that relatively small events were enough to trigger feelings that life was not worth living (63.9% yes; 30.6% maybe; 5.6% no). Further, the majority (57.6% yes; 21.5% yes, but only if asked; 20.8% ‐ no) reported they would be willing to tell their therapist/doctor about their thresholds of unacceptable loss.ConclusionThe construct of unacceptable loss deserves further empirical inquiry. Individuals contemplating suicide set them and if the loss occurs, it may trigger suicidal action in suicide ready individuals. Thresholds could provide risk assessment and safety planning data currently being overlooked.
SARS-CoV-2 transmission in schools in Korea: nationwide cohort study
Authors: Choe Young June , Park Young-Joon , Kim Eun-Young , Jo Myoungyoun , Cho Eun Young , Lee Hyunju , Kim Yun-Kyung , Kim Yae-Jean , Choi Eun Hwa 
Published: December 2021

ObjectiveThere is an urgent public need to readdress the school closure strategies. We aimed to describe the epidemiology of COVID-19 in schools and school-aged children to understand their roles in transmitting SARS-CoV-2 in Korea.DesignRetrospective cohort study.SettingAll schools in KoreaPatientsAll school-aged children in Korea.InterventionsNone (observational study).Main outcome measuresIncidence rate, proportion of affected schools.ResultsBetween February and December 2020, the incidence rate was lower among school-aged children (63.2–79.8 per 100 000) compared with adults aged 19 and above (130.4 per 100 000). Household was the main route of transmission (62.3%), followed by community (21.3%) and school clusters (7.9%). Among the schools in Korea, 52% of secondary schools had COVID-19 cases, followed by 39% of primary schools and 3% of kindergartens.ConclusionsWe found that schools and school-aged children aged 7–18 years were not the main drivers of COVID-19 transmission. The major sources of transmission were households.
Ray tracing intraocular lens calculation performance improved by AI-powered postoperative lens position prediction
Authors: Li Tingyang , Reddy Aparna , Stein Joshua D , Nallasamy Nambi 
Published: December 2021

AimsTo assess whether incorporating a machine learning (ML) method for accurate prediction of postoperative anterior chamber depth (ACD) improves cataract surgery refraction prediction performance of a commonly used ray tracing power calculation suite (OKULIX).Methods and analysisA dataset of 4357 eyes of 4357 patients with cataract was gathered at the Kellogg Eye Center, University of Michigan. A previously developed machine learning (ML)–based method was used to predict the postoperative ACD based on preoperative biometry measured with the Lenstar LS900 optical biometer. Refraction predictions were computed with standard OKULIX postoperative ACD predictions and ML-based predictions of postoperative ACD. The performance of the ray tracing approach with and without ML-based ACD prediction was evaluated using mean absolute error (MAE) and median absolute error (MedAE) in refraction prediction as metrics.ResultsReplacing the standard OKULIX postoperative ACD with the ML-predicted ACD resulted in statistically significant reductions in both MAE (1.7% after zeroing mean error) and MedAE (2.1% after zeroing mean error). ML-predicted ACD substantially improved performance in eyes with short and long axial lengths (p<0.01).ConclusionsUsing an ML-powered postoperative ACD prediction method improves the prediction accuracy of the OKULIX ray tracing suite by a clinically small but statistically significant amount, with the greatest effect seen in long eyes.