bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge of osteopathic manipulative medicine and osteopathic physicians in a New York South Asian community
Authors: Lee Jasmine , Maung Chun , Espares Jenzel , Chen Justin , Yip Frenda , Lin Willis , Zhao Lauren , Li To Shan 
Published: July 2021

Abstract

Context
Research regarding patient awareness of osteopathic manipulative medicine (OMM) can help identify barriers and factors limiting patient knowledge. Levels of knowledge about OMM and osteopathic physicians have been studied in New York’s Chinese and Korean populations, but have not previously been investigated in the South Asian population.

Objectives
To assess the knowledge of OMM and osteopathic physicians within a South Asian community of New York.

Methods
A cross-sectional study was designed in which a culturally appropriate survey, provided in both English and Hindi, was administered to study participants in order to measure knowledge of osteopathic medicine. The study utilized convenience sampling and distributed surveys to individuals who identified themselves of South Asian descent at high traffic sites in Hicksville, New York. The survey contained 10 questions, assessing the individual’s knowledge of osteopathic medicine. The Kruskal–Wallis and Chi-Square tests were employed to determine statistical significance of the data obtained from the surveys.

Results
The survey was conducted on 100 participants in Hicksville, New York. The respondent demographics included 53 males and 47 females with an average age of 41.2 ± 16.3 years old. There were 34 (34%) participants who had heard of osteopathic manipulative medicine (OMM) and 26 (26%) participants who had knowledge of doctor of osteopathic medicine (DO) physicians. Respondents were found more likely to have knowledge of DOs if they were born in the United States (US) vs. other countries (US, 8 of 14 [57.1%] vs. others, 18 of 86 [20.9%]; p=0.006) or lived longer in the US (11 of 26 [42.3%], p=0.039). Participants who spoke a non-English primary language were also found less likely to have knowledge of DOs as they made up 46 of the 58 respondents who indicated no knowledge (79.3%, p=0.042).

Conclusions
A general lack of knowledge of DOs and OMM exists within the South Asian community of Hicksville, New York and lower levels of awareness were found among participants who were male, born outside the US, had a language other than English as their primary language, and had spent less time in the US. Additional educational resources may be implemented to increase awareness of DOs and OMM among this and similar communities.
Global epidemiology of mucopolysaccharidosis type III (Sanfilippo syndrome): an updated systematic review and meta-analysis
Authors: Kong Weijing , Wu Shanshan , Zhang Jing , Lu Cheng , Ding Yingxue , Meng Yan 
Published: July 2021

Abstract

Objectives
Mucopolysaccharidosis III, an autosomal recessive lysosomal storage disorder, is characterized by progressive mental retardation and behavioral problems. Meta-analysis of global mucopolysaccharidosis III epidemiology, which serves as a fundamental reference for public health decision-making, was not available prior to this study. To provide a systematic review and meta-analysis of birth prevalence of mucopolysaccharidosis III in multiple countries.

Methods
MEDLINE and EMBASE databases were searched for original research articles on the epidemiology of mucopolysaccharidosis III from inception until 1st July, 2020. A checklist adapted from STROBE (STrengthening the Reporting of OBservational studies in Epidemiology) was used to assess the quality of all studies involved. Meta-analysis, adopting a random effects logistic model, was performed to estimate pooled birth prevalence of mucopolysaccharidosis III and its subtypes.

Results
Twenty-five studies screened out of 1,826 records were included for data extraction. The pooled global mucopolysaccharidosis III birth prevalence was 0.76 cases (95% CI: 0.57–0.96) per 100,000 live births. The pooled global birth prevalence of mucopolysaccharidosis III subtypes (A, B, and C) was 0.52 cases (95% CI: 0.33–0.72), 0.21 cases (95% CI: 0.12–0.30) and 0.01 cases (95% CI: 0.005–0.02) per 100,000 live births, respectively.

Conclusions
Based on the global population size (7.8 billion) and the life span of patients, there would be 12–19 thousand mucopolysaccharidosis III patients worldwide. To our knowledge, this is the first comprehensive systematic review that presented quantitative data fundamental for evidence-based public health decision-making by evaluating global epidemiology of mucopolysaccharidosis III.
Bildung und Mahayana-Buddhismus
Authors: Makabe Hiromoto 
Published: July 2021

Abstract
Hier wird die bisher wenig erläuterte, aber sehr wichtige Frage thematisiert, wie der Mahayana-Buddhismus, besonders die Wahre Sekte des Reinen Landes, in der Rezeption der deutschen Pädagogik und Philosophie in Japan funktionierte, indem ich die allgemeine Pädagogik von Masao Fukushima (1889-1979) als ein Beispiel aufgreife. Er versuchte, die deutsche Pädagogik aufgrund des eigenen traditionellen Gedankengutes original zu akzeptieren und seine eigene Pädagogik zu etablieren. Paradoxerweise behauptet die Wahre Sekte des Reinen Landes, dass man die Perfektion erst erreichen kann, wenn man auf den „Eigene-Kraft-Glaube“ („Jiriki“) verzichtet, der auf die vernünftige Kontrolle der Natur und des Selbst abzielt. Dieser Glaube steht eigentlich in Konflikt mit der modernen Erziehungsidee, also Autonomie oder Selbstbestimmung. Ich zeige, wie Fukushima versuchte, dieses Dilemma zu überwinden.
Optimization of Antibiotic Prophylaxis Delivery for Pediatric Surgical Procedures
Authors: Yalamanchi Pratyusha , Parent Ashley L. , Baetzel Anne E. , Crowe Susan M. , Gutting Andrew A. , Gisondo Gino , Portice Lynda C. , Thorne Marc C. , Wagner Deborah S. , Bates Katherine E. , Tribble Alison C. 
Published: July 2021

OBJECTIVES
To optimize prophylactic antibiotic timing and delivery across all surgeries performed at a single large pediatric tertiary care center.

METHODS
A multidisciplinary surgical quality team conducted a quality improvement initiative from July 2015 to December 2019 by using the A3 problem-solving method to identify and evaluate interventions for appropriate antibiotic administration. The primary outcome measure was the percentage of surgical encounters for pediatric patients with appropriate timing of antibiotic administration before surgical incision. Surgical site infection rates was the secondary outcome. Intervention effectiveness was assessed by using statistical process control.

RESULTS
A total of 32 192 eligible surgical cases for pediatric patients were completed during the study period. Identified barriers to timely perioperative antibiotic administration included failure to order antibiotics before the surgical date and lack of antibiotic availability in the operating room at the time of administration. Resulting sequential interventions included updating institutional guidelines to reflect procedure-specific antibiotic choices and clarifying timing of administration to optimize pharmacokinetics, creating a hard-stop antibiotic order within electronic health record case requests, optimizing pharmacy and nursing workflow, and implementing an automatic antibiotic prophylaxis timer in the operating room. Administration of prophylactic antibiotics during the recommended preincision time window significantly improved; the correct timing was recorded in 38.6% of preintervention cases versus 94.0% at the conclusion of rollout of the sequential interventions (P &lt; .001). Surgical site infection rates remained stable.

CONCLUSIONS
Here we demonstrate utility of the A3 problem-solving schematic to successfully optimize prophylactic antibiotic timing and delivery in the surgical setting for pediatric patients by implementing systems-based interventions.
“Tayní”: variedad de frijol común Mesoamericano de grano rojo brillante
Authors: Chaves Barrantes Néstor Felipe , Hernández Fonseca Juan Carlos , Araya Villalobos Rodolfo , Rosas Sotomayor Juan Carlos 
Published: July 2021

Introducción. El frijol de grano rojo es el segundo más consumido en Costa Rica. El mercado penaliza el precio del grano rojo oscuro y exige variedades de tono claro y brillante, aunque, las personas productoras requieren cultivares resistentes a patógenos y de alto potencial de rendimiento. Objetivo. Describir el proceso de desarrollo y las principales características agronómicas de la variedad Tayní. Materiales y métodos. Esta variedad se derivó del cruzamiento triple Tío Canela 75 // SRC1-1-18 / SRC 1-12-1 realizado en 1999 en la Escuela Agrícola Panamericana (Honduras). Fue evaluada en Costa Rica entre el 2002 y el 2008, por el Instituto Nacional de Innovación y Transferencia en Tecnología Agropecuaria y la Universidad de Costa Rica. El comportamiento y características agronómicas de Tayní se determinaron con base en la información obtenida de la evaluación de 4 viveros de adaptación, 28 ensayos de rendimiento y 32 parcelas de validación, llevados a cabo bajo manejo del productor en 12 localidades de Costa Rica. La variedad se liberó el 23 de febrero del 2012 en Pueblo Nuevo, Upala, Alajuela. Resultados. Tayní es una variedad de grano rojo claro brillante, que obtuvo un rendimiento de 1450 kg.ha-1 bajo manejo de la empresa productora y de 2063 kg.ha-1 en condiciones experimentales. Posee un hábito de crecimiento tipo II, resistencia intermedia a Pseudocercospora griseola (mancha angular) y a Thanatheporus cucumeris (mustia hilachosa), y resistencia a los virus del mosaico común (gen I) y del mosaico dorado amarillo (gen bgm-I y QTL mayor SW12). La tonalidad del rojo de su grano (grado 5) es de mayor valor comercial que la de Cabécar (grado 6). Bajo condiciones lluviosas, el grano de Tayní se decolora menos que el de Cabécar (1,1 y 2,8%, respectivamente). Conclusiones. La tonalidad del color rojo del grano y menor porcentaje de decoloración, le dan a Tayní ventaja comercial con respecto a Cabécar, la variedad de grano rojo más sembrada en Costa Rica
Jumping plant lice (Hemiptera, Psylloidea) in rest stops of Hungarian highways
Authors: Kontschán Jenő , Ripka Géza , Kiss Balázs 
Published: July 2021

AbstractIn the framework of a survey of arthropods in rest stops of Hungarian highways, 19 species of jumping plant lice were collected. Three species belong to the family Aphalaridae, one to Calophyidae, two to Liviidae, nine to Psyllidae and four to Triozidae. Two species (Livilla variegataandTrioza neglecta) are alien, non-indigenous species; the others are native to Hungary. The most abundant species wereCalophya rhois,Cacopsylla melanoneuraandTrioza neglecta. The specimens ofC.melanoneurawere found in 20,T. neglectain 10 andC. rhoisin 6 localities out of the 31 rest stops surveyed.
ON THE KOLMOGOROV-WIENER FILTER FOR RANDOM PROCESSES WITH A POWER-LAW STRUCTURE FUNCTION BASED ON THE WALSH FUNCTIONS
Authors: Gorev V. N. , Gusev A. Yu. , Korniienko V. I. , Safarov A. A. 
Published: July 2021

Context. We investigate the Kolmogorov-Wiener filter weight function for the prediction of a continuous stationary random process with a power-law structure function.
Objective. The aim of the work is to develop an algorithm of obtaining an approximate solution for the weight function without recourse to numerical calculation of integrals.
Method. The weight function under consideration obeys the Wiener-Hopf integral equation. A search for an exact analytical solution for the corresponding integral equation meets difficulties, so an approximate solution for the weight function is sought in the framework of the Galerkin method on the basis of a truncated Walsh function series expansion.
Results. An algorithm of the weight function obtaining is developed. All the integrals are calculated analytically rather than numerically. Moreover, it is shown that the accuracy of the Walsh function approximations is significantly better than the accuracy of polynomial approximations obtained in the authors’ previous papers. The Walsh function solutions are applicable in wider range of parameters than the polynomial ones.
Conclusions. An algorithm of obtaining the Kolmogorov-Wiener filter weight function for the prediction of a stationary continuous random process with a power-law structure function is developed. A truncated Walsh function expansion is the basis of the developed algorithm. In opposite to the polynomial solutions investigated in the previous papers, the developed algorithm has the following advantages. First of all, all the integrals are calculated analytically, and any numerical calculation of the integrals is not needed. Secondly, the problem of the product of very small and very large numbers is absent in the framework of the developed algorithm. In our opinion, this is the reason why the accuracy of the Walsh function solutions is better than that of the polynomial solutions for many approximations and why the Walsh function solutions are applicable in a wider range of parameters than the polynomial ones. The results of the paper may be applied, for example, to practical traffic prediction in telecommunication systems with data packet transfer.
C-reactive protein: pathogenetic characteristics and possible therapeutic target
Authors: Utkina E. A. , Afanasyeva O. I. , Pokrovsky S. N. 
Published: July 2021

It is known that the key mediator of acute phase response and marker of inflammation is C-reactive protein (CRP), the study of the role of which in the development of not only cardiovascular, but also infectious diseases has acquired particular relevance at the present time. CRP can be involved in all stages of the atherosclerotic process, including activation of the complement system and vascular endothelial cells, thrombosis, lipid accumulation, and apoptosis.The review describes modern concepts of the structure, biological and pathophysiological properties of CRP, its value as a cardiovascular risk predictor, as well as existing methods for reducing its blood level.According to recent studies, cardiovascular patients who achieved lower CRP levels with drug therapy had better clinical prognosis, making CRP an attractive therapeutic target. Currently, a search is underway for approaches to correct CRP levels associated with both the development of novel drugs and therapeutic apheresis methods to remove CRP from blood plasma.
Prediction of 5-year survival in patients with heart failure and implanted cardiac resynchronization therapy devices
Authors: Soldatova A. M. , Kuznetsov V. A. , Gorbatenko E. A. , Enina T. N. , Malishevsky L. M. 
Published: July 2021

Aim. Based on clinical parameters and diagnostic investigations, to create a complex model of personalized selection of patients with heart failure (HF) for cardiac resynchronization therapy (CRT). To establish the diagnostic value of the created model in predicting 5-year survival.Material and methods. The study included 141 patients with HF (men, 77,3%; women, 22,7%). The mean age of patients at the time of implantation was 60,0 [53,0; 66,0] years. All patients had New York Heart Association (NYHA) class II-IV HF, left ventricular ejection fraction (LVEF) ≤35%, and QRS ≥130 ms. Patients were randomly divided into training (n=95) and test (n=36) samples, which were comparable in main clinical and functional characteristics.Results. The index included parameters that had a significant relationship with 5-year survival according to the Cox regression: male sex, prior myocardial infarction, hypertension, QRS <150 ms, no left bundle branch block, PR ≥200 ms with sinus rhythm/absence of radiofrequency ablation in atrial fibrillation, NYHA class III, IV HF, LVEF <30%, left ventricular end-diastolic volume ≥235,0 ml, NT-proBNP ≥2692,0 ng/ml. All variables were scored based on the в-coefficients. In the training sample, a value ≥45 points demonstrated a sensitivity of 82,4% and a specificity of 67,2% in predicting 5-year survival (AUC, 0,873; p<0,001). The index use on the test sample showed comparable results (AUC, 0,718; p=0,020; sensitivity — 71,4%, specificity — 62,5%). Also, in the training sample, the index ≥45 points was associated with1-year survival (sensitivity — 84,6%, specificity — 58,1%, AUC, 0,811; p<0,001).Conclusion. An index of personalized selection for CRT has been created, which makes it possible to accurately predict the 5-year survival rate, as well as the 1-year survival rate, regardless of the current selection criteria.
Lessons learned
Authors: Hoaglund Erica P. , Smith Christopher E. 
Published: July 2021

The Plains Hognose Snake (Heterodon nasicus) has been the focus of many studies due, in part, to this species' interesting morphological characteristics and death-feigning behavior. However, significant gaps exist in our understanding of this species' natural history. Often perceived to be a semi-fossorial species in the literature, our data suggests that this species spends the majority of its time during the active season above ground. In addition, we provide some of the first data on communal hibernation for this species. Also discussed are observations on nocturnality, oophagy, and reproduction. Given that the plain Hognose Snake is imperiled in many of the states and provinces in which it occurs, additional research is needed to better inform in-situ conservation efforts.
Differential habitat use by Common Watersnakes (Nerodia sipedon)
Authors: Neuman-Lee Lorin A. , Durso Andrew M. , Kiriazis Nicholas M. , Olds Melanie J. , Mullin Stephen J. 
Published: July 2021

Understanding intraspecific variation in habitat use is important for the management of any species. In many studies of reptiles, habitat use by juveniles is poorly understood when compared to their adult conspecifics because of capture biases and logistical constraints. We compared habitat use between sexes and age classes of Common Watersnakes (Nerodia sipedon) at a reservoir in central Illinois. Juvenile N. sipedon occurred more frequently in habitat with high conopy cover, whereas adults N. sipedon, especially reproductive females, were found exclusively in habitat with no canopy cover. Adult males used both locations equally. We emphasize the need to investigate ontogenetic variation in habitat use to better understand how reptiles utilize diverse anthropogenically altered landscapes.
Amphibian and Reptilian Inventories Augmented by Sampling at Heronries
Authors: Vyas Raju , Parasharya B.M. 
Published: July 2021

An alternate method for supporting amphibian and reptilian inventory was tested. This experimental method involved the collection of regurgitated food from water bird nestlings from a total of 10 heronries: four mixed-species and six single-species heronries in Gujarat State, India, during 1997 to 1999. We verified the presence of twelve species of amphibians, and twelve species of reptiles were recovered intact.
Various methods are used to evaluate the diversity of amphibians and reptiles, many of which are resource-dependent in terms of both time and money (e.g., Heyer et al. 1994). The verification process in such diversity surveys generally requires the collection of voucher specimens for establishing the credibility of the work (Dubois and Nemesio 2007; Funk et al. 2005). Vouchers also facilitate further taxonomic studies and the identification of cryptic species, especially when species complexes occupy the area being surveyed. The collection of specimens requires permission from the appropriate government authority. Because relevant authorities in India are often hardcore believers of the philosophy of “Jiv Daya” (a Jainist concept involving compassion for all beings) and unaware of the need for voucher specimens, acquisition of permits to collect in protected areas (sanctuaries and national parks), even for studies of biodiversity and environmental assessments is extremely difficult. Even when permission for voucher collection is granted, strict time constraints are imposed. These render surveys of large areas almost impossible, particularly because vouchers ideally involve a series of specimens of various species (Goodman and Lanyon 1994) and collection methods often are very time consuming. Consequently, methods that are less time-consuming and less expensive are needed. Herein, we test one such alternative.
On the taxonomy of snakes in the genus Leptodeira, with an emphasis on Costa Rican species
Authors: Barrio-Amorós César L. 
Published: July 2021

Considerable confusion surrounds the taxonomy of snakes in the genus Leptodeira, which contains 12 currently recognized species. Herein I review the genus and recognize 15 species based on previously published morphological and genetic data. Easily recognized traits can be used to identify Costa Rican species of Leptodeira, and taxonomic insights into all species in the L. annulata-septentrionalis complex are discussed. Photographs of all currently recognized species and subspecies are included.
Features of postural control in children with severe forms of idiopathic scoliosis
Authors: Nikityuk I. E. , Vissarionov S. V. 
Published: July 2021

Objective. The study of postural stability in children with severe degrees of idiopathic scoliosis and assessment of body balance disorders after surgical correction of spinal deformity.
Material and methods. The study of 18 patients aged 1417 years with idiopathic scoliosis of the IIIIV degree with localization of the main arc according to Lenke I, III, V and VI was conducted. The vertical balance of the body was evaluated using a stabilometric platform MBN "Biomechanica" (LLC "MBN", Moscow) before and 910 days after the surgical correction of spinal deformity using transpedicular spinal systems. The results were compared with a stabilometric survey of 18 healthy children.
Results. In patients with idiopathic scoliosis before surgery, a decrease in the stability of the vertical balance of the body, manifested by pronounced deviations from the nominal values of the stabilometric parameters, was revealed. The correlation analysis showed a pathologically strong relationship between the length L, the area S and the amplitude of fluctuations of the pressure center A in patients statokinesiograms compared to the group of healthy children.
In the immediate postoperative period, the postural control system disorders are aggravated in patients.
Conclusions. In children with severe idiopathic scoliosis, violations of the postural control system were revealed, which led to the formation of a suboptimal motor stereotype due to dysfunction of sensorimotor integration.
Morphological basis for possibility of applying electrochemical method with use of nanotechnological biosensors in diagnosis of colorectal cancer
Authors: Belkin A. N. , Freind G. G. , Kochetov A. G. 
Published: July 2021

Objective. To assess the efficacy of electrochemical method using biosensors for studying the activity of alkaline phosphatase as a marker of functional atypism in the fresh and formalin-fixed biopsies of the colorectal cancer by means of comparing with the results of morphological study.
Materials and methods. Electrochemical method was used to study the fragments of tumors (adenocarcinomas) of the colon and colon mucosa from 78 patients who underwent endoscopic study of the colon. The results of electrochemical and morphological studied were assessed and compared.
Results. In the material from 70 patients, a mean value of the current strength, obtained while studying the tumor fragments, was 49.2 (95 % CI 41.3 88.9) nA and 33.1 (95 % CI 9.5 44.2) nA in case of fresh and formalin-fixed biopsies, respectively. A mean value of the current strength, obtained while studying mucosa fragments, was 119.7 (95 % CI 96.8 167.1) nА and 59.6 (95 % CI 48.3 71) nA in case of fresh and formalin-fixed biopsies, respectively. While conducting immunohistochemical study, in the tumor tissue a low expression of alkaline phosphatase compared to unchanged mucosa was detected.
Conclusions. Electrochemical method applying nanotechnological biosensors was shown to be used for a rapid, direct estimation of alkaline phosphatase content in the biopsies of the colorectal carcinoma. The obtained results allow considering electrochemical method as an additional method for assessment of functional atypism of tumor cells.