bluuebunny/crossref_metadata_2025_split huggingface dataset:
A 3D Printing Personalized Percutaneous Nephroscope Puncture Guide Plate in Percutaneous Nephrolithotomy: A Pilot Study
Authors: Keyu Gao , Shuaishuai Li , raj Ashok , Shuofeng Li , Shuai Liu , Yuan Zhang , Haitao Zhu , Junqi Wang 
Published: September 2021

Abstract
Objective Using CTU, combined with 3D printing technology, digital design, the development of individualized PCNL) puncture guides, preliminary discussion of its feasibility for PCNL puncture positioning.Methods Twenty-two patients with renal calculi who underwent PCNL in the hospital of Xuzhou Medical University in 2017-2018, including 10 experimental groups, used 3D printing technology to make guides (puncture guides); simulated punctures in vitro, after clearing the needle angle, PCNL was performed in 10 patients and PCNL in 12 patients in the control group. The accuracy of puncture positioning, puncture time and intraoperative blood loss were compared between the two groups.Results In the experimental group, 10 patients had good puncture guide plate and the patient's skin. The puncture needle was puncture under the guidance of the guide plate and verified by the color Doppler. The 1 needle puncture was successful 100.00% (10/10), the positioning of the needle point, the depth of the puncture. The angles were consistent with the preoperative design. The success rate of 12 cases of color Doppler ultrasound in the control group was 75.00% (9/12). There was no significant difference between the two groups (P>0.05). The amount of hemorrhage was (7.78±0.94) min and (49.31±6.43) mL, respectively. The control group was (9.04±1.09) min and (60.08±12.18) mL, respectively. The two groups were statistically significant (P<0.05). Conclusion 3D printing personalized percutaneous nephrolithotomy guide can improve the accuracy of PCNL renal puncture channel positioning, shorten the puncture time and reduce intraoperative blood loss, and provide a new method for PCNL renal puncture positioning, which is worthy of further clinical exploration.
A Novel Methodology for Simultaneous Minimization of Manufacturing Objectives in Tolerance Allocation of Complex Assembly
Authors: Nagarajan Lenin , Mahalingam Siva Kumar , S Ayyappan , Natarajan Eswara Prasath 
Published: September 2021

Abstract

A novel methodology is presented in this work to minimize the manufacturing objectives, namely tolerance cost and machining time for allocating optimum tolerance to the components of complex assemblies with considering the proper process and machine selections from the given alternatives. A methodology that provides a two-step solution is developed for this work. First, a heuristic approach is applied to determine the best machine for each process, and then a combined Whale optimization algorithm with a univariate search method is used to allocate optimum tolerances with the best process selection for each sub-stage/operation. The efficiency of the proposed novel methodology is validated by solving two typical tolerance allocation problems of complex assemblies: a wheel mounting assembly and a knuckle joint assembly. Compared with previous approaches, the proposed methodology showed a considerable reduction in tolerance cost and machining time in relatively less computation time.
Molecular Detection of Brucella spp. in Ruminant Herds in Greece
Authors: Katsiolis Aristomenis , Papanikolaou Eleni , Stournara Athanasia , Giakkoupi Panagiota , Papadogiannakis Emmanouil , Zdragas Antonios , Giadinis Nektarios , Petridou Evanthia 
Published: September 2021

Abstract
Brucellosis is a worldwide distributed infectious disease. Ruminants and other animal species (swine, dogs, equids etc), as well as wild mammals can be affected. The disease can be transmitted to humans through the food chain or by direct contact with infected animals. Because of the relatively high economic burden due to abortions within a herd, significant efforts have been employed and hence the disease in most European countries has been eradicated. Accordingly, Greece applies both control and eradication programs concerning small ruminants (sheep and goats) and bovines depending on the geographical area. Current challenges in the standard antibody-based laboratory methods used for Brucella detection are the failure to differentiate antibodies against the wild strain from the ones against the vaccine strain Rev1 and antibodies against B. melitensis from those against B. abortus. The aim of the study was to modify previously published protocols based on PCR analysis and to generate a new diagnostic tool able to confirm the doubtful results delivered from serology and mainly to do easier and more reliable the detection of Brucella. For this reason, 264 samples derived from 191 ruminants of the farm and divided in 2 groups (male/female) were examined with a modified DNA extraction and PCR protocol. Molecular examination revealed the presence of Brucella spp. in 39 out of 264 samples (derived from 30 animals). In addition, Brucella spp. was detected in infected tissues derived from testicles, inguinal lymph nodes, fetal liver and fetal stomach content molecular detection of than other infected tissues.
The Empirical Research on the Impact of Pro-Environmental Factors on the Financing Cost of Green Bond
Authors: Zhang Chunlian , Liu Ziming , Zeng Yuqing , Yang Ou 
Published: September 2021

Abstract
Green bonds are an important part of green finance and a significant financing method for enterprises to make socially responsible investments. This thesis analyzes the impact of pro-environmental factors on the financing cost of green bonds by the data of green bonds issued from 2016 to 2020. The results show that the better the environmental performance of the issuer's region, the lower the financing cost of green bonds, and the third-party certification reduces the financing cost of green bonds. Further research shows that high pollution areas and high pollution industries enhance the punitive role of environmental pollution financing. Regional environmental performance mainly affects the financing cost of green bonds through tax suppression mechanism and credit penalty mechanism, while third-party certification affects the financing cost of green bonds through tax relief mechanism and financing channel mechanism. This paper provides empirical evidence and policy inspiration for reducing the financing cost of issuing green bonds and promoting the perfection of the green bond system.
Seismic Landslide Susceptibility Assessment Using Principal Component Analysis And Support Vector Machine
Authors: Xu Ziyao , Che Ailan , Cao Yanbo , Zhang Fanghao 
Published: September 2021

Abstract
Seismic landslides are dangerous natural hazards, causing immense damage in terms of human lives and property. Susceptibility assessment of earthquake triggered landslide is the scientific premise and theoretical basis of disaster emergency management of engineering. The aim of this study is to applied the seismic landslide susceptibility model to Dayong Expressway in Chenghai area prone to frequent earthquakes. Support vector machine is used to establish the assessment model based on the data of 716 landslides caused by Ludian Ms6.5 earthquake in 2014. To improve the universality of the assessment model in different regions. Principal component analysis (PCA) is used for reducing the dimension of landslide conditioning factors and weaking difference of the regional characteristics between historical earthquake regions with Dayong expressway area. To applied the SVM model for seismic landslide susceptibility in Dayong Expressway region where the conditioning factors information is similar to Ludian area. Gutenberg-Richter model and Dieterich model are used to assume an earthquake in Chenghai area for landslide susceptibility assessment. Inverse distance weight (IDW) method is used for assessing the landslide risk class of Dayong Expressway. The results show that the “Very high” landslide susceptibility class account for 0.63% of Chenghai area. The seismic landslide has the most obvious impact on the middle 13 km section of Dayong expressway and this section account for 8.9% is defined as high-risk class. The study verifies the practicability of the seismic landslide susceptibility model based on machine learning and provides constructive reference for the susceptibility assessment of engineering facilities under earthquake.
The Effect of Nitric Oxide on Amaranthus Tricolor L. Under Cadmium Stress
Authors: Baniasadi Fatemeh , Arghavani Masoud , Saffari Vahid Reza , Mansouri Mehdi 
Published: September 2021

Abstract
This study aimed to appraise the crosstalk between sodium nitroprusside (SNP), as a source of nitric oxide (NO), and cadmium (Cd) toxicity on growth and physiological traits in Amaranth tricolor L. by using different multivariate statistical methods. The results showed that growth-related traits of A. tricolor were significantly reduced (p<0.05) under Cd stress. Contrarily, Cd treatments increased lipid peroxidation and reduced total protein content. Delving on the results of SNP application showed the suitability of its medium level (100 µM) on increasing the growth-related traits and also plant tolerance to Cd stress via lowering the lipid peroxidation and radical molecules production due to the higher activities of superoxide dismutase and catalase. Increasing the amount of Cd in roots and shoots, as the results of Cd treatment, reduced the growth and production of A. tricolor plants by high rates (over 50% in 60 mg kg-1 Cd level) indicating its susceptibility to high Cd toxicity. Contrarily, treating plants with NO showed no effect on shoot Cd content, while it significantly increased Cd allocation in the root, which might be attributable to the protective effect of NO on Cd toxicity by trapping Cd in the root. Subsequently, the application of a medium level of SNP (around 100 µM) is recommendable for A. tricolor plant to overcome the negative impacts of Cd toxicity.
Assessment of Aerosol Generating Events During the Nasopharyngeal Swabbing for SARS-CoV-2 Detection
Authors: Cismaru Cosmin-Andrei , Chira Sergiu , Cismaru Gabriel-Laurentiu , Nutu Andreea-Mihaela , Netea Mihai-Gheorghe , Berindan-Neagoe Ioana 
Published: September 2021

Abstract
Background: A variety of medical procedures are classified as aerosol generating. However there is no consensus on whether some procedures such as nasopharyngeal swabbing can generate aerosols. During specimen collection, the contact of the nasopharyngeal swab with the respiratory mucosa often triggers defense reflexes such as sneezing and coughing, which generate airborne particles. The accumulation and persistence of a viral load from infectious aerosols for hours after their generation can represent a threat for increased spread of infection. Methods: Prospective observational cohort study in individuals tested for RT-PCR SARS-CoV-2 from July to October 2020. Participants were evaluated for the occurrence of aerosol generating events (AGEs) triggered by the nasopharyngeal swabbing. We used descriptive statistics to analyze the data set and the chi-square test for AGE comparison between sexes. Results: Among 1239 individuals, we reported 264 in which AGEs were triggered by the specimen collection. 97 individuals tested positive for SARS-CoV-2, of which 20 presented AGEs. There were no significant differences in the occurrence of AGEs by age, but significant differences have been identified between sex and the occurrence of AGEs both in the SARS-CoV-2 negative and SARS-CoV-2 positive individuals. Conclusions: The risk of coughing or sneezing triggered by the nasopharyngeal swabbing was high among tested individuals. Testing facilities should ensure adequate availability of personal protective equipment (PPE) for the testing personnel, ensure appropriate ventilation of the rooms, and develop additional strategies to limit the risk of contamination of other participants to the testing session from potentially infectious and persistent aerosols.
Research on Health Evaluation and Operation and Maintenance Decision of Intelligent Distribution Network Based on Health Index Theory
Authors: yang yang 
Published: September 2021

Abstract
To solve the problems of dynamic state evaluation of large-scale distribution equipment and complex and changeable smart grid, and realize efficient planning, operation and maintenance. Based on the existing literature, this paper explores the distribution network health index theory and distribution network operation and maintenance strategy. The distribution network planning method based on health index is studied. Based on the existing power system research indexes, the suitable intelligent grid evaluation indexes are selected from the aspects of safety, economy, reliability and environmental protection, and an index system for comprehensive evaluation of smart distribution network health is selected. The critical characteristics of distribution network are classified, the indexes are established and the distribution network health grades are divided by analytic hierarchy process and entropy weight method. In this paper, the evaluation method is used to calculate the health index, classify the health degree and generate the health degree image for seven lines in a 110kv substation in oil field. According to the optimal operation and maintenance strategy of distribution network based on health index theory, it provides a reliable basis for distribution network planning, construction, operation and maintenance.
Risk Factors for Early Seizure After Revascularization in Patients With Moyamoya Disease
Authors: Niu Hongchuan , Tan Cunxin , Jin Kehan , Duan Ran , Shi Guangchao , Wang Rong 
Published: September 2021

Abstract
Background
To investigate the risk factors of early seizure after revascularization in patients with moyamoya disease (MMD).
Methods
A total of 298 patients with MMD diagnosed in our hospital from 2015 to 2018 were analyzed retrospectively. We summarized the characteristics of seizure after revascularization in patients with MMD and analyzed the predictors of early postoperative seizure.
Results
We identified 15 patients with MMD who developed seizures within 1 week after revascularization. According to logistic regression analysis, age (OR:1.04, 95% CI 0.998–1.086; P = 0.060), and infarct side (OR:1.92, 95% CI 0.856–4.290; P = 0.113) were not significantly associated with incident early seizure. Postoperative infarction (OR:12.89, 95% CI 4.198–39.525; P = 0.000) and preoperative cerebral infarction (OR:4.08, 95% CI 1.267–13.119; P = 0.018) were confirmed as risk factors for early seizure.
Conclusions
We believe that history of preoperative infarction and new infarction are independent risk factors of early seizure in patients with MMD after revascularization.
Lessons Learnt From Typhoons Fitow and In-Fa: Implications for Improving Urban Flood Resilience in Asian Coastal Cities
Authors: Chan Faith , Gu Xinbing , Qi Yunfei , Thadani Dimple R. , Chen David Yongqin , Lu Xiaohui , Li Lei , Griffiths James , Zhu Fangfang , Li Jianfeng , Chen Wendy Y. 
Published: September 2021

Abstract
Frequent typhoons are significantly affecting the coastal cities via intensive rainstorms, tidal surges and strong wind. Natural factors such as climate change and global sea-level rise come alongside anthropogenic factors such as rapid urbanisation and land use/land cover change leading to detrimental consequences such as urban floods. This short communication offers various lessons learnt by Ningbo municipality from two strong typhoons that hit the city directly, namely “Fitow” in 2013 and “In-Fa” in 2021. On the one hand, the usage of “Big Data” and “Social Media” for bettering “Preparation” and “Prevention” reduced flood impacts significantly. On the other hand, the implementation of “Flood Insurance” speed up the “Recovery” processes. The successful “Preparation”, “Response” and “Recovery” helped Ningbo to enhance its flood resilience, and thus substantial impacts of injuries, household damages and associated economic loss were avoided. These three key terms should be heeded in typhoon/flood governance in which various stakeholders are involved with, and be incorporated into the city’s long-term strategic development plans to merge with the climate actions towards 2030s and beyond. This will be vitally important in reducing climatic hazards and improving coastal flood resilience under the future climatic uncertainties in Asian coastal cities. (196 words)
Redefining Student Learning Objectives for the General Medicine / Primary Care Clinical Clerkship ~ The Way to Implement Community Based Medical Education
Authors: Miyazaki Kei , Ie Kenya , Kitamura Masaru , Takamura Akiteru 
Published: September 2021

Abstract
Background: Mie University is one of the first medical schools to initiate a community-based clinical clerkship in general medicine. The curriculum was developed over fifteen years ago based on the personal expertise of the general medicine faculties. The purpose of this project is to update and revise the curriculum and learning objectives by integrating the ideas of community primary care physicians and university faculties involved in clinical clerkships.Methods: We have conducted semi-structured interviews with community primary care physicians. The interviews were based on keywords extracted from the preliminary research. Two researchers independently reviewed the free-coded interview transcripts, organized them into thematic units using thematic analysis, and then discussed and merged them into one list between the two researchers. This list was shared and discussed among the four researchers to create a new curriculum and learning objectives.Results: Nine primary care physicians participated in group interviews and 11 participated in individual interviews. The following themes were identified: 1.role of primary care 2.contextual care 3.hospital-clinic collaboration 4.multidisciplinary care/inter-professional work 5.work-life balance 6.health economics 7.health promotion 8.health policy 9.common problems/common diseases. Conclusion:We have redefined the learning objectives of the general medicine clinical clerkship. The abstracts have been made more specific, which will be more helpful for both teachers and learners.
Bisphenol S Promotes the Progression of Prostate Cancer by Regulating the Expression of COL1A1 and COL1A2.
Authors: Fang Kai , Li Yang , Zhang Yuqing , Liang Shengjie , Li Simin , Liu Dong 
Published: September 2021

Abstract
In recent decades, Bisphenol S (BPS), which have been considered as alternatives for Bisphenol A (BPA), have become widely used in personal care products, paper products and food. Clarifying the relationship between bisphenol and tumors is of great significance for the treatment and prevention of diseases. In this work, we discovered a new method to predict the correlation between bisphenol interactive genes and tumors. The transcriptome profile and interactive genes of bisphenol were obtained from the Cancer Genome Atlas and Genotype-Tissue Expression, Comparative Toxicology Genomics and PharmMapper database. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis showed that interactive genes were mainly enriched in prostate cancer. Gene targetd prediction and gene set variation analysis proved that bisphenol exert potential effects on prostate cancer. The operating characteristic curves and survival analysis showed that role of COL1A1 and COL1A2 in predicting the prognosis of prostate cancer. Cell counting kit-8 assay demonstrated that the cells with BPS-treated could remarkably promote the cell proliferation ability in both PC-3 and LNCap cells. Wound healing assay and the transwell assay demonstrated that the cells with BPS-treated could significantly promote the cell invasion capacity of prostate cells. Two key genes, COL1A1 and COL1A2, were significantly upregulated with BPS-treated in the PC-3 and LNCap cells.
Is Mindful Eating Higher in Individuals With Orthorexia Nervosa ?: A Cross-Sectional Study
Authors: Demirer Büşra , Yardımcı Hülya 
Published: September 2021

Abstract
Purpose

The present study aimed to investigate the relationship between mindful eating and Orthorexia Nervosa (ON) among adults and contribute to establishing ON diagnostic criteria.
Methods

In the current cross-sectional study, 105 females, 92 males (aged 19–64 years), were enrolled whose scores on the Orthorexia Nervosa Questionnaire-15 (ORTO-15) and the Eating Attitudes Test-26 (EAT-26) and SCOFF scales indicated a prevalence of ON and eating disorder risk. In addition, Mindful Eating Questionnaire (MEQ) was applied to participants to determine mindful eating.
Results

In participants with ON, the scores of emotional eating and conscious eating scores, which are MEQ sub-factors, and the total score of MEQ are higher than those who do not have ON (p < 0.05). There was a negative correlation between MEQ and ORTO-15 scores (r = -0.269; p < 0.01). In addition, the one-point increase in the ORTO-15 scores of the participants led to 0.094 decrease in MEQ scores (B = -0.094; SE = 0.021; p < 0.001) and 0.175 decrease in EAT-26 scores (B = -0.175; SE = 0.033; p < 0.001).
Conclusions

The data obtained from our study show that mindful eating of individuals with ON is higher than those who do not have ON and this is important in determining the diagnostic criteria of ON.
Level of evidence:
V, Cross-sectional descriptive study.
A Case of Two Shunts In The Endovascular Treatment of Type II Abernethy Syndrome
Authors: Bombardier Brenden , Alli Adam , Rohr Aaron , Collins Zachary , Raval Kavi 
Published: September 2021

Abstract
Background:Abernethy malformation is a rare condition defined by a congenital extrahepatic portosystemic shunt, often leading to absence or hypoplasia of the intrahepatic portal venous system. Although there are no consensus treatment guidelines, interventional techniques now offer minimally invasive treatment options for Abernethy malformations. This case report describes a case of Abernethy Syndrome Type II where the patient had two separate extrahepatic portosystemic shunts treated with endovascular occlusion with two Amplatzer plugs and demonstrates the feasibility of this treatment for this rare condition. This case was in a young adult, adding to the scarce literature of treatment for Abernethy syndrome in the adult population.Case Presentation:We report a case of a 20-year-old female patient with neurocognitive behavioral difficulty, voracious appetite, and chronic encephalopathy secondary to type II Abernethy malformation with not one, but two extrahepatic portosystemic shunts. The patient had failed medical management and was not a liver transplant candidate. Therefore, she presented to us for an endovascular treatment option. The two shunts were treated with endovascular occlusion using Amplatzer vascular plugs. Following embolization, flow into the hypoplastic portal vein improved with near complete occlusion of flow into the portosystemic shunts, thus restoring blood flow into the native portal system. At 3 month follow up, a CT demonstrated complete occlusion of the two portosystemic shunts, and a portal vein diminutive in caliber. The portal vein measured 7mm in diameter on both pre and post-procedure CT scans. The total volume of the liver was found to be 843 cm3 on pre-procedure CT & 1191 cm3 on post-procedure CT.Conclusions:This report demonstrates the feasibility of using endovascular embolization to treat Abernethy II malformations. The management strategy of Type II Abernethy Syndrome should be to redirect blood flow into the hypoplastic native portal system, allowing for physiologic hepatic metabolism of splanchnic blood, hypertrophy of the portal system, and growth of the liver from the increased trophic flow.