bluuebunny/crossref_metadata_2025_split huggingface dataset:
Selected aspects of end-of-life care in the Intensive Therapy Unit
Authors: Miętkiewicz Sylwia , Siczyńska Bożena , Dyk Danuta 
Published: April 2021

End-of-life (EOL) care represents a significant component of palliative/hospice care. It is applied in terminal hours, days or weeks of life, which require a very scrupulous, professional protection and paliative treatment, targeted at alleviation of sufferings. Mortality in wards of anaesthesiology and intense therapy (ICU) reaches 17%-24% and frequently, despite application of modern therapeutic methods, the patient dies. This paper aims at drawing readers’ attention to selected aspects of care given to patients and their families in the end-of-life in ICU. Dying represents a very difficult process not only for the patient and his/her family but also for the staff taking care over the patient. It represents a dynamic process and, therefore, the management should be modified depending on altering condition of a patient and his/her relatives; it is linked to adaptation of care and symptomatic treatment and to meeting half-way anxieties of patient’s relatives. The patient should be viewed in his/her entire set of biological, psychic, spiritual and social needs and it should be born in mind that securing an appropriate comfort of terminal moments in life is occasionally more important than a heroic battle for every minute of life. In the terminal period of life quality of life depends on an appropriate communication, acceptance that the patient and his/her family keep the key for undertaking decisions, for a continuous care, emotional support, for assurance of an appropriate care, correct symptomatic treatment, spiritual, emotional and organizational support.
Cerebrovascular mediated subclinical brain injury – interaction between cardiovascular function, brain structure and cognitive function – study rationale, design and principal methods
Authors: Katulska Katarzyna , Minczykowski Andrzej , Piskorski Jarosław , Wykrętowicz Mateusz , Stajgis Marek , Guzik Przemysław , Wykrętowicz Andrzej 
Published: April 2021

Project entitled “Cerebrovascular mediated subclinical brain injury – interaction between cardiovascular function, brain structure and cognitive function- study rationale, design and principal methods” is a cross-sectional study in a group of older individuals with no apparent symptoms of stroke, transient ischemic attacks or cognitive impairment. The primary aim of the projects is further our understanding of the patomechanism of cerebrovascular disease associate brain injury as well as vascular cognitive impairment and give a better insight into the interplay between arterial wall, ventriculo-vascular coupling, wave reflection and pulsatility of the flow and how these interplays are mirrored by MRI neuroimaging. With our novel, interdisciplinary approach, we will define the methodology and build tools for those who want to follow in this challenging and non-standard direction.
Induction of UDP-glucuronosyltransferase 1A by naturally occurring phytochemicals in human hepatoma cells
Authors: Krajka-Kuźniak Violetta , Krysztofiak Adam , Paluszczak Jarosław 
Published: April 2021

UDP-glucuronosyltransferases (UGTs) are important detoxification and drug-metabolizing enzymes, which catalyse the glucuronidation of exogenous and endogenous chemicals. The anti-carcinogenic activity of dietary phytochemicals is partly attributed to the induction of phase II enzymes, including UGT1A. Our earlier study showed that protocatechuic acid increased UGT activity in rat liver. A similar effect was observed for indole-3-carbinol and phenethyl isothiocyanate in rat liver. In this study we assessed the effect of protocatechuic acid, tannic acid, indole-3-carbinol and phenethyl isothiocyanate on the expression and protein level of UGT1A in hepatocellular carcinoma HepG2 cells. Cells were incubated with 2µM and 10µM of protocatechuic acid, tannic acid, or indole-3-carbinol and 1µM and 5µM of phenethyl isothiocyanate for 72 hours. Transcript level was measured by RT-PCR and protein level by the immunoblot assay. Treatment with protocatechuic acid, tannic acid, indole-3-carbinol and phenethyl isothiocyanate induced the expression and protein level of UGT1A. Phenethyl isothiocyanate increased the mRNA of UGT1A to the most extent (0.28–5.7 fold change, p < 0.05). Increased expression of UGT1A was accompanied by the enhancement of its protein level, with the exception of protocatechuic acid at the dose of 2µM. Overall, isothiocyanates and indoles were more potent as UGT inducers than phenolic acids. Collectively, the results suggest that the induction of UGT1A could contribute to the hepatoprotective and chemopreventive properties of these phytochemicals.
The role of microparticles in pathomechanisms of diabetic retinopathy – analysis of intercellular communication mechanisms in endothelial aging. Case control study in patients with metabolic syndrome, diabetes type 1 and type 2
Authors: Stępień Ewa , Szuścik Iwona , Tokarz Aleksandra , Enguita Francisco J. , Solnica Bogdan , Żurakowski Aleksander , Małecki Maciej 
Published: April 2021

The project is proposed to explain the role of specific circulating microparticles (MPs) as conveyors in trafficking bio-active molecules in type 1 (T1DM) and type 2 (T2DM) diabetic patients with risk of diabetic retinopathy (DR) and in patients with metabolic syndrome (MS). The possible role of miRNAs as modulators of these processes (in switching on/off mechanism on the molecular level) is proposed. An increased number of MPs with respect to glucose concentrations and levels of proangiogenic factors in vivo (patients’ plasma) is expected. The relationship between age of patents and MP content (cell membrane glycoproteins, phosphatidylserine or miRNA profile) is possible. MPs will be obtained from T1DM (n = 30) T2DM (n = 30), MS (n = 30) and controls (n = 30). Retinopathy in diabetic patients will be assessed by imaging method. Biological profile of MPs will be assessed in vitro by means of flow cytometry, molecular biology methods and cell proliferation assays.
Kajian Status Hara N, P, K Tanah Pada Sawah Tadah Hujan (Studi Kasus Tiga Desa di Kecamatan Beringin)
Authors: Benauli Arkhiadi 
Published: April 2021

<p>Soil fertility status describes soil characteristics and soil suitability with the plants to be cultivated. This study aims to identify the variable soil fertility that becomes an obstacle in several villages in the Beringin District. This research was conducted in the villages of Aras Kabu, Kelapa, and Serdang, Beringin District, Deli Serdang Regency. This research is descriptive using the survey method. Sampling of soil in the survey area was carried out sequentially with a purposive random sampling method. The results showed that the total N status in the three villages was classified as low. Where the total N value in Aras Kabu village was 0.13%, Kelapa village 0.12% and Serdang village was 0.21%. Phosphorus in the research field is classified as high. In the village of Aras, the district was 19.57 ppm, Kelapa village 19.27 ppm and Serdang village 13.19 ppm. The K<sub>2</sub>O value in the study area was also low, where the village of Aras Kabu was only 19.96 mg K<sub>2</sub>O/100 g, Kelapa village 18.56 mg K<sub>2</sub>O/100g and Serdang village 25.47 mg K<sub>2</sub>O/100g. The use of P fertilizers can be reduced as an implication of the status of P nutrients available in high land, while to increase the low levels of N and K nutrients, it can be done by providing organic matter in the form of fertilizer (compost or cage) or returning post-harvest straw to the land. </p>
DESIGNING AN EFFECTIVE ORGANIZATIONAL STRUCTURE TO ACHIEVE PUBLIC ORGANIZATION OBJECTIVE (CASE STUDY IN PT. PTPN VII LAMPUNG)
Authors: Yulianti Devi , Hermawan Dedy 
Published: April 2021

<p>This research is about the design of organization structure to create the effective public organization which is located in PT. Perkebunan Nusantara VII (Persero) Lampung. This research is aimed to describe and analyze the relation between the design of organization structure of PTPN VII (Persero) with the company goals in creating the effective corporation. This study used qualitative approach with descriptive method. The data was collected using documentation tehcnique and the data analysis was using reduction and conclusion technique. The results of this research were three main points. First, PTPN VII (Persero) has used the divisional structure. Second, there were some alterations in divisional structure each year from 2008 until 2012. Third, the divisional structure of PTPN VII (Persero) hasn’t been able to support the achievement of company goals so that this corporation is no yet effective. The conclusion of this research is that the design of organization structure of PTPN VII (Persero) is not effective to reach the company goals.</p><p> </p><p>Keywords: organization, organization structure, and organization effectiveness. </p>
Analisis Good Governance Dalam Pengelolaan Keuangan Desa
Authors: Utomo Kabul Setio , - Sudarmo Setio , Suharto Didik G. 
Published: April 2021

<p>Penelitian ini bertujuan untuk: Menganalisis akuntabilitas, transparansi dan responsivitas pengelolaan keuangan Desa di Desa Campurasri Kecamatan Karangjati, Kabupaten Ngawi. Penelitian ini menggunakan metode penelitian deskriptif kualitatif. Teknik pengambilan sampel untuk menentukan informan dilakukan dengan <em>purposive </em>sampling. Pengumpulan data dilakukan melalui wawancara mendalam, observasi dan dokumentasi. Sedangkan validitas data yang digunakan adalah triangulasi sumber, serta analisis data dengan menggunakan model data berlangsung atau mengalir (<em>flow model analysis</em>). Hasil Penelitian ini menunjukkan bahwa akuntabilitas, transparansi dan responsivitas dalam pengelolaan keuangan Desa Campurasri sudah berjalan namun masih belum maksimal. Aspek Akuntabilitas dalam pengelolaan keuangan sudah dilakukan secara horizontal (<em>horizontal accountability</em>) yaitu pertanggungjawaban kepada masyarakat luas, dilakukan dalam forum musyawarah desa dan pertanggungjawaban. Laporan Keterangan Pertanggungjawaban yang disampaikan kepada Badan Permusyawaratan Desa dan pertanggungjawaban vertical <em>(vertical accountability)</em> yaitu pertanggungjawaban atas pengelolaan dana kepada otoritas yang lebih tinggi. Transparansi pengelolaan Keuangan masih belum dikelola secara maksimal. Beberapa pos tertentu dalam laporan keuangan hanya diketahui oleh kepala desa dan bendahara desa, Laporan yang disampaikan ke publik hanyalah belanja umum yang menyangkut belanja pembangunan, sedangkan belanja yang menyangkut urusan kedalam ( Alat Tulis Kantor, perjalanan Dinas, Honorarium dan sebagainya) hanya diketahui oleh internal pemerintah Desa saja. Responsivitas pemerintah Desa dalam pelayanan informasi keuangan kepada masyarakat sudah dijalankan namun belum sesuai harapan pengguna layanan. Keluhan yang disampaikan terkait dengan pengelolaan keuangan desa ditampung untuk kemudian dijanjikan penyelesainnya. Beberapa keluhan ditindaklanjuti, namun keluhan yang lain hanya ditampung tidak ditindaklanjuti sesuai harapan dan bahkan ada juga keluhan yang justru sudah dimentahkan di depan dengan alasan prosedur sudah dilakukan sesuai aturan.</p><p><strong>Kata Kunci: Akuntabilitas, Good Governance, Keuangan Desa</strong></p>
Peningkatan Public Trust dan Pengaruhnya Terhadap Kepatuhan Wajib Pajak di Provinsi Sulawesi Selatan
Authors: Haning Muhamad Thahir , - Hasniati , Tahili Mashuri H. 
Published: April 2021

<p>Artikel ini bertujuan untuk menganalisis dan menginterpretasi pengaruh model kepercayaan publik terhadap kepatuhan wajib pajak di Provinsi Sulawesi Selatan. Pendekatan penelitian menggunakan analisis kuantitatif dengan metode survey di tiga area Kantor Pelayanan Pajak yaitu Makassar Selatan, Maros, dan Palopo. Populasi dalam penelitian ini adalah wajib pajak yang telah teregistrasi sebagai wajib pajak, baik pajak orang pribadi dan pajak badan sebanyak 2400 orang. Sampel penelitian menggunakan multistage cluster sampling methods untuk memastikan keterwakilan populasi. Penarikan sampel menggunakan metode stratified random sampling terhadap tiga area penelitian. Rumus Slovin digunakan untuk menetapkan jumlah sampel sebesar 20% dengan pertimbangan karena populasi yang relatif besar dimana persentase kelonggaran ketelitian kesalahan pengambilan sampel yang masih bisa ditolerir sebesar α=0,05. Dengan dasar tersebut, maka sampel dalam penelitian ditetapkan sebanyak 400 responden. Teknik analisis data menggunakan teknik analisis kuantitatif dengan menggunakan persamaan model struktural. Hasil penelitian ini menunjukkan bahwa kepercayaan publik berpengaruh positif dan signifikan terhadap kepatuhan wajib pajak. Kepercayaan publik berpengaruh positif dan signifikan terhadap kepatuhan wajib pajak melalui kinerja pelayanan pajak. Variabel kinerja pelayanan pajak berpengaruh positif dan signifikan terhadap kepatuhan wajib pajak. Faktor pemerintah, faktor resiko, dan faktor kontekstual berpengaruh positif dan signifikan terhadap kepercayaan publik dalam meningkatkan kepatuhan wajib pajak di Provinsi Sulawesi Selatan. </p><p><strong>Kata kunci : Kepercayaan publik, kinerja pelayanan pajak, kepatuhan wajib pajak</strong></p>
DAFTAR ISI
Authors: Jurnal Administrasi Publik Spirit Publik : 
Published: April 2021

<strong><span style="font-size: small;">Spirit Publik : Jurnal Administrasi Publik</span></strong><span>diterbitkan oleh Program Studi Ilmu Administrasi Negara Fakultas Ilmu Sosial dan Politik Universitas Sebelas Maret (UNS). Jurnal ini menyajikan hasil penelitian dan artikel dalam lingkup kajian kebijakan dan manajemen publik. </span><strong>Spirit Publik : Jurnal Administrasi Publik</strong><span> terbit 2 (dua) edisi dalam satu tahun pada Edisi April dan Oktober. Jurnal telah memiliki e-issn 2580-3875 dan p-issn 1907-0489. </span>
Historical masonry churches diagnosis supported by an analytic-hierarchy-process-based decision support system
Authors: Sangiorgio Valentino , Martiradonna Silvia , Fatiguso Fabio , Uva Giuseppina 
Published: April 2021

<p class="Abstract"><span lang="EN-GB">The structural and anti-seismic performances of historical masonry churches are related not only to structural damage and masonry quality but also to other criticalities that can jeopardise the connections, wooden elements, and non-structural elements. As such, the technical and scientific communities are interested in the development of fast visual-survey approaches for assessing these issues and for performing exhaustive diagnostics by considering all the parameters affecting the building performance.</span></p><p class="Abstract"><span lang="EN-GB">In this paper, a new procedure for performing rapid visual surveys and the diagnostics of masonry buildings using a set of condition ratings is proposed. The proposed novel approach includes three synergistically related techniques: i) the analytic hierarchy process method for measuring and analysing both qualitative and quantitative data during a visual survey, ii) a suitable survey form to perform a rapid visual inspection implementable in a decision support system (DSS), and iii) a DSS procedure to provide a powerful computerised tool that would be useful in large-scale data acquisition. Finally, to demonstrate the potential of the proposed approach, the Romanesque masonry church SS. Salvatore in Capurso, Italy,</span><span lang="EN-GB">is analysed. A comparison with a standard diagnostic workflow is also presented to validate the procedure and to emphasise the advantages of the novel diagnostics.</span></p><p class="Abstract"> </p>
Are the “100 of the world’s worst” invasive species also the costliest?
Authors: Cuthbert Ross , Diagne Christophe , Haubrock Phillip J. , Turbelin Anna J , Courchamp Franck 
Published: April 2021

Abstract
Biological invasions are increasing worldwide, damaging ecosystems and socioeconomic sectors. Two decades ago, the “100 of the world’s worst” invasive alien species list was established by the IUCN to improve communications, identifying particularly damaging ‘flagship’ invaders globally (hereafter, worst ). Whilst this list has bolstered invader awareness, whether worst species are especially economically damaging and how they compare to other invaders (hereafter, other ) remain unknown. Here, we quantify invasion costs using the most comprehensive global database compiling them (InvaCost). We compare these costs between worst and other species against sectorial, taxonomic and regional descriptors, and examine temporal cost trends. Only 60 of the 100 worst species had invasion costs considered as highly reliable and actually observed estimates (median: US$ 43 million). On average, these costs were significantly higher than the 463 other invasive species recorded in InvaCost (median: US$ 0.53 million), although some other species had higher costs than most worst species. Damages to the environment from the worst species dominated, whereas other species largely impacted agriculture. Disproportionately highest worst species costs were incurred in North America, whilst costs were more evenly distributed for other species; animal invasions were always costliest. Proportional management expenditures were low for the other species, and surprisingly, over twice as low for the worst species. Temporally, costs increased more for the worst than other taxa; however, management spending has remained very low for both groups. Nonetheless, since 40 species had no robust and/or reported costs, the “true” cost of “some of the world’s worst ” 100 invasive species still remains unknown.
Does Integrated Medical Insurance System (IMIS) Alleviate the Difficulty of Using Cross-Region Health Care for the Migrant Parents in China
Authors: Ma Chao , Huo Shutong , Chen Hao 
Published: April 2021

Abstract
Background: A large number of internal immigrants in the process of urbanization in China is Migrant Parents, the aging group who move to urban area involuntarily to support their family. They are more vulnerable economically and physically than the younger migrants. However, the fragmentation of rural and urban health insurance schemes divided by “hukou” household registration system limit migrant’s access to healthcare services in their resident location. Some provinces have started to consolidate the Urban Resident Basic Medical Insurance and the New Rural Cooperative Medical Scheme as one Integrated Medical Insurance Schemes (IMIS) to reduce the disparity between different schemes and increase the health care utilization of migrants. Results: Using China Migrants Dynamic Survey, we used OLS for regression in models. We found that the migrant parents who are covered by the IMIS are more likely to choose inpatient service and to seek medical treatment in the migrant destination, by improving the convenience of medical expense reimbursement and relieving the economic pressure. Conclusions: The potential mechanisms of our results could be that IMIS alleviates the difficulty of seeking medical care in migrant destinations by improving the convenience of medical expense reimbursement and relieving the economic constrain.
Research on Tool Presetting and Tool Deviation in CNC Lead Screw Grinding Process
Authors: Hu Donghong , Wang Kai , Zhang Ling , Wang Pingjiang , Chen Guang 
Published: April 2021

Abstract
In the process of tool presetting for an CNC lead screw grinding, when A-axis rotating and Z-axis shifting synchronously according to the screw pitch length, L, of the lead screw workpiece, the handwheel corresponding to X-axis and Z-axis, respectively, is operated to align the grinding wheel with the middle of the screw groove. Then, the coordinates of Z-axis, A-axis and X-axis of the current position are recorded, and the coordinates of the grinding start position and grinding end position of the lead screw workpiece are calculated accordingly.However, due to the mutual following error of Z-axis and A-axis in the synchronous movement process, tool deviation typically occurs when the grinding wheel moves from the grinding start position to the grinding end position to grind the lead screw workpiece. More specifically, the grinding wheel slightly deviates from the middle of the screw groove to the left or right of the screw groove.To offset this deviation, the root cause for creating the deviation is analyzed, and a method to correct the tool deviation is proposed: First, the CNC system sends out grinding instructions, according to the requirements of grinding process, to make the A-axis and the Z-axis move synchronously. In the meantime, the CNC system measures and records the current coordinates of A-axis and Z-axis, and calculates the tool deviation caused by the mutual following error between Z-axis and A-axis. As a result the grinding start position and the grinding end position are adjusted in light of the value of tool deviation in the subsequent grinding process, so as to address the tool deviation issue.
The Moderating Role of Natural Resources Between Institutional Quality and CO2 Emissions: Evidence From Developing Countries
Authors: Muhammad Bashir 
Published: April 2021

Abstract
The recent study aim is to scrutinize the moderating role of natural resources between institutional quality and carbon dioxide (CO2) emissions in 106 developing countries from 1996 to 2017 by using dynamic fixed effect, generalized method of moments (GMM) and system generalized method of moments (system GMM) estimators as well as apply the instrumental fixed effect, the instrumental time fixed effect and instrumental system GMM estimators as robustness. We make use of dynamic models and instrumental system GMM to reduce the result of autocorrelation increasing from misspecification of a model as well as clear the biases from unnecessary data and solve the possible endogeneity issues. The empirical results indicate that financial development, trade, and institutional factors: corruption perception control, government effectiveness, political stability, regulatory quality, rule of law, and voice and accountability play a vital role in CO2 emissions reduction but natural resources along with economic growth are the core factors that cause CO2 emission in developing countries. On the opposing, natural resources boost the indirect impact of institutional quality on CO2 emissions in developing countries.
Effect of Different Selenium Precursors on Structural Characteristics and Chemical Composition of Cu2ZnSnSe4 Nanocrystals
Authors: Kakherskiy Stanislav Igorovich , Pshenychnyi Roman , Dobrozhan Oleksandr , Vaziev Jaroslav , Opanasyuk Anatoliy , Gnatenko Yuriy 
Published: April 2021

Abstract
In the presented work Cu2ZnSnSe4 nanocrystals have been synthesized by the polyol method. The chemical composition, morphological, structural, and microstructural properties of Cu2ZnSnSe4 nanocrystals depending on synthesis temperature and time as well as precursor composition have been thoroughly investigated using scanning and transmission electron microscopies, energy dispersive X-ray analysis, X-Ray diffraction, FTIR spectroscopy. We compared the properties of nanocrystals synthesized from different precursors containing selenourea or amorphous selenium as a source of selenium and then determined the optimal conditions for nanocrystals synthesis. It was found that the optimal synthesis time for nanocrystals obtained using the first approach was t = (30-45) min, and for the second approach t = 120 min. It was also found that the optimal composition for the synthesis of single-phase Cu2ZnSnSe4 nanocrystals by the second approach is the molar ratio of precursors 2:1.5:1:4 and synthesis temperature T = 280 оС. Cu2ZnSnSe4 nanocrystals synthesized under optimal conditions were used to develop nanoinks for printing solar cell absorbers by 2D and 3D printers.