bluuebunny/crossref_metadata_2025_split huggingface dataset:
ESTILO DE VIDA EM UNIVERSITÁRIOS: ANÁLISE SOBRE ESTUDANTES QUE APRESENTAM DIFERENTES FORMAS DE ATIVIDADE LABORAL
Authors: Guimarães Theodoro Henrique , Prati Sérgio Roberto Adriano 
Published: July 2021

A vida de estudante universitário abrange diferentes aspectos da rotina individual. Isso depende também das condições sociais ao qual o universitário se enquadra, dentre elas se a vida de estudantes está relacionada a atividades laborais formais, não formais ou algum outro tipo de renda. Analisar o estilo de vida (EV) de universitários que mantém condição de atividades laborais durante o curso de graduação. A pesquisa descritiva exploratória teve participação de 1381 universitários, sendo que 1064 (77,0%) alegaram ter algum tipo de renda. Todos responderam ao questionário padronizado Estilo de Vida Fantástico (AÑEZ; REIS; PETROSKI, 2008) que é composto por 25 questões em escala likert com respostas possíveis de 0 a 4 pontos totalizando 100pontos. Quanto maior o escore mais saudável e seguro é o EV. Não houve diferenças (P>0,05) entre as médias do EV entre universitários com renda e sem renda. No caso masculino, os universitários sem renda apresentaram em média EV maior do que os com renda. Houve diferença entre EV dos universitários de turnos diferentes independentes se apresentam ou não renda, sendo que quando estudantes do período integral, o EV sempre foi caracterizado como melhor em relação ao EV de estudantes do período noturno. Os bolsistas obtiveram EV mais seguro. O EV dos universitários é predominantemente inadequado, sendo que isso é independente de se ter ou não alguma renda, contudo, no caso masculino, quando se tinha alguma renda o EV era inadequado. Além disso, universitários participantes de projetos com bolsa e EV mais saudáveis eram predominantes.
Educational collaboration of Russian libraries: The possibilities and prospects
Authors: Kudrina E. L. , Matveeva N. S. 
Published: July 2021

Collaboration is one of the most efficient forms of cooperation within the system of continuing library and information education. The study is based on general scientific methods, including that of institutional analysis. The study subject is collaboration as an instrument of interaction and joint efforts, wшер the results to be actualized through exchange of knowledge, experience and skills in a specific educational ecosystem. The study object is collaboration within the system of continuing library professional education. With resource, organizational and process approaches, the essence of the concept of "collaboration" is identified; the focus is made on its special institutional structure and role in efficient interaction between the subjects of knowledge economy. The essence of the definition of "educational collaboration" is revealed, taking into account the inherent features and various individual approaches to its interpretation. The experience in building the collaboration of library continuing education providers, i.e. "LENINKA" Corporate University of the Russian State Library and Department of Continuing Professional Education of the State Public Scientific and Technological Library of the Russian Academy of Sciences Siberian Branch, is analyzed (20192020). The special role of collaboration in providing continuing professional education to Russian library specialists is emphasized. It is demonstrated that collaboration in education facilitates co-organization of professional communities, render their activities more efficient and highly demanded within the digital economy and knowledge society.
Implementasi Kurikulum Pembelajaran Islamic Studies dalam Membentuk Sikap Spiritual Siswa
Authors: Nur Mawaddah Islamiyah  , Reksiana  
Published: July 2021

This research aims to determine the process of implementing an "Islamic studies" curriculum in shaping students' spiritual attitudes at the International Islamic Secondary School of Republic of Indonesia (IISS RI). This research method uses a qualitative method that is descriptive of analysis with data collection techniques observation obtained from interviews, and documentation. The researcher found that the implementation of "Islamic studies" curriculum was carried out in two ways, namely through academic programs that emphasized cognitive and affective aspects and non-academic programs which emphasized psychomotor aspects, with the application of "Islamic studies" curriculum to shape students' spiritual attitudes such as obeying Allah swt, being sincere, confident, responsible, diligent in learning, honest, disciplined, and respecting others. In addition, the researcher found that the "Islamic studies" curriculum also had a specific target that had to be fulfilled by the students as a requirement for graduation which was by memorizing the Qur'an juz 29 and 30, memorizing the hadith, memorizing dhikr and prayer and being able to give religious lectures.
MENINGKATKAN PERKEMBANGAN BAHASA ANAK DENGAN PERMAINAN MENYAMBUNG CERITA DI KELOMPOK B TK NEGERI 01SANGIR JUJUAN KECAMATAN SANGIR JUJUAN KABUPATEN SOLOK SELATAN
Authors: Mardianis Mardianis 
Published: July 2021

Permasalahan yang ditemukan dalam penelitian ini adalah kemampuan perkembangan bahasa anak masih rendah. Hal ini terjadi karena permainan menyambung cerita yang digunakan guru kurang menarik dalam pembelajaran, bahkan anak bingung untuk mengunakannya. Pemilihan perkembangan bahasa dengan permainan menyambung cerita yang tidak tepat oleh guru menjadi penyebab terjadinya kondisi ini dan anak juga kurang memuaskan dalam perkembangan bahasa anak dengan permainan menyambung cerita.
Tujuan penelitian ini untuk meningkatkan perkembangan bahasa anak di kelompok B TK 01 Sangir Jujuan Kecamatan Sangir Jujuan Kabupaten Solok Selatan. Subjek penelitian ini anak kelompok B dengan jumlah anak 13 orang terdiri dari 6 perempuan dan 7 laki-laki. Jenis penelitian ini adalah Penelitian Tindakan Kelas (PTK) dilakukan dalam dua siklus dengan tahapan masing-masing siklus sebagai berikut: perencanaan, pelaksanaan, pengamatan, refleksi, dan dokumentasi, kemudian diolah dan di analisis dengan rumus persentase.
Manfaat Penelitian Tindakan Kelas (PTK) ini adalah agar kemampuan perkembangan bahasa anak dengan permainan menyambung cerita meningkat. Hasil penelitian rata- rata persentase kemampuan perkembangan bahasa anak dapat dilihat dari sebelum tindakan, sampai siklus II. Sebelum tindakan kemampuan bahasa anak masih rendah, pada siklus I mulai meningkat namun belum mencapai KKM. Pada siklus II meningkat lagi sehingga sudah melebihi Kriteria Ketuntasan Minimal ( KKM) yang ditetapkan.
Berdasarkan hasil Penelitian Tindakan Kelasa (PTK) dilakukan dapat disimpulkan bahwa permainan menyambung cerita di kelompok B terjadi peningkatan, yaitu persentase perkembangan bahasa anak pada indikator 1, siklus I 39% pada siklus II meningkat menjadi 85%, perkembangan bahasa anak pada indikator 2, siklus I 54% pada siklus II meningkat menjadi 77%, perkembangan bahasa anak pada indikator 3, siklus I 38%, pada siklus II meningkat menjadi 77%, dan perkembangan bahasa anak pada indikator 4, siklus I 54 %, pada siklus II meningkat menjadi 69%. Pada siklus II perkembangan bahasa anak sudah meningkat, ini dapat dilihat dari hasil nilai yang sudah banyak mendapatkan kategori BSH dan BSB. Sehingga dapat disimpulkan bahwa PTK ini berhasil meningkatkan perkembangan bahasa anak dengan permainan menyambung.
STRATEGI PENGEMBANGAN OBJEK WISATA PEMANDIAN LUBUK MATA KUCING KOTA PADANG PANJANG
Authors: Yolveri Yolveri 
Published: July 2021

The city government of Padang Panjang has developed several tourism objects, one of which is the Lubuk Mata Kucing bath because there are still not many tourism who have not seen the object, due to the location which is on the outskirts of the city and road directions to tourism objects are still lacking, then indirectly affect the level of tourism visits.
The Lubuk Mata Kucing bath is indeed very minimal promotion and exposes tourism objects to the crowd, so you do not see this beautiful tourism attraction, in addition to the lack of promotion in the facilities section.
The Indonesian government has tried to make Indonesia one of the tourism destinations for tourism and make Indonesia the main destination for tourism, tourism who visit many tourism objects in Indonesia automatically improve the economy of local residents and foreign exchange, as is being done by the Padang government. Panjang In making improvements to one of the tourism objects, namely the Lubuk Mata Kucing bath, to be a better tourism attraction.
The development of the world of tourism and increased competition in the Tourism Industry of the Padang Panjang City Government, especially the Tourism Office, should carry out various development strategies so that tourism in the City of Padang Panjang is not left behind as one of the Lubuk Mata Kucing bathing objects that can develop and attract tourism to visit. The Municipal Government of Padang Panjang cooperates with other parties that are expected to increase the level of tourist visits.
ANALISIS VALIDASI KEDALAMAN GERUSAN AKIBAT ALIRAN DITIKUNGAN SUNGAI DENGAN METODE RIPLEY
Authors: Maizir Maizir 
Published: July 2021

Fenomena aliran yang melewati tikungan di sungai sangat menarik untuk diamati. Pada aliran yang cukup besar umumnya dapat menyebabkan dinding ditikungan sungai sebelah luar longsor dan terjadinya gerusan/erosi pada dasar sungainya, sementara ditikungan sebelah dalam terjadi endapan sedimen. Pada sungai yang dindingnya terdiri dari pasangan batu dengan dasar sungai tanah, gerusan akan terjadi pada dasar sungai.
Dalam penelitian ini dilakukan pengamatan terhadap hasil analisis kedalaman gerusan ditikungan sungai sebelah luar dengan rumus Ripley, dan membandingkannya hasil pengukuran penampang gerusan yang terjadi ditikungan sungai sebelah luar. Rumus Ripley biasanya digunakan untuk menentukan dengan gerusan yang terjadi ditikungan sungai sebelah luar di lapangan. Lokasi pengamatan dilakukan ditikungan sungai batang Kuranji dibawah jembatan Siteba. Penelitian dimulai dengan melakukan pengukuran situasi trase dan penampang sungai di lapangan, menentukan debit banjir tahunan berdasarkan data curah hujan untuk mengetahui besar dan kedalaman muka air banjir, mengkalibrasi data debit banjir dengan kondisi lapangan, menganalisis konvigurasi penampang sungai berdasarkan rumus Ripley dan membandingkannya dengan hasil pengukuran lapangan. Secara umum dapat ditarik kesimpulan bahwa kedalaman gerusan yang dihitung dengan rumus Ripley sebanding dengan kedalaman gerusan hasil pengukuran di lapangan.
Dan rekomendasi Chow bahwa untuk keperluan praktis, pemakaian rumus Ripley dalam merencanakan penampang lintang di tikungan sungai memberikan hasil yang memuaskan, terbukti benar.
ON SOME NEW HERMITE-HADAMARD TYPE INEQUALITIES FOR FUNCTIONS WHOSE nTH DERIVATIVES ARE (mü 1; mü 2)- STRONGLY CONVEX
Authors: KILINÇ YILDIRIM Seda , YILDIRIM Hüseyin 
Published: July 2021

The aim of this paper, is to establish some new inequalities of
Hermite-Hadamard type by using (mü 1; mü 2)-strongly convex function via whose
nth derivatives in absolute value at certain powers. Moreover, we also consider
their relevances for other related known results.
Caracterización y evolución clínica de los pacientes con cáncer de próstata metastásico resistente a la castración atendidos en el servicio de urología de SOLCA (Guayaquil). 2013 a 2019
Authors: Rendón Marcos , Torres Luis Ullauri , León Jhon Castillo , Romero Proaño Sandro Patricio 
Published: July 2021

Introducción: El cáncer de próstata constituye la segunda neoplasia más frecuente después del cáncer pulmonar. Es la Primera causa de incidencia de cáncer en la población ecuatoriana, mientras que la mortalidad ocupó el segundo lugar. Enzalutamida retrasa significativamente la necesidad de quimioterapia y la disminución de la calidad de vida. En algunos estudios se ha encontrado disminución del riesgo de muerte y retraso en el inicio de la quimioterapia así como aumento de la supervivencia post-quimioterapia con su uso. El objetivo del presente estudio fue caracterizar la evolución clínica de pacientes con cáncer de próstata metastásico resistente a la castración (mCRPC) tratados con enzalutamida.
Metodología: Se recopiló información de pacientes atendidos en el servicio de Urología de Solca - Guayas del año 2013 al 2019. Se incluyeron todos los casos con cáncer de próstata metastásico resistente a la castración.
Resultados: El promedio de edad fue de 77.3 ± 9.9 años. El tamaño inicial prostático fue de 59.9 ± 43.7 g. Los síntomas con mayor frecuencia registrados fueron: hematuria 18,8%, disminución del chorro miccional 18.8%, polaquiuria y poliuria con 14.6% cada uno. . La supervivencia global fue del 80% en los casos tratados con enzalutamida. Ninguna muerte estuvo asociada con el uso de enzalutamida. En el 66,6% se registraron eventos adversos. De todos los eventos adversos registrados el 82.3% fueron leves. Conclusión: La supervivencia global en el grupo estudiado estuvo acorde a los reportes de supervivencia en pacientes tratados con enzalutamida. La terapia con enzalutamida fue bien tolerada.
Impacto en la reducción de la morbilidad utilizando la técnica de ganglio centinela en pacientes con cáncer de mama
Authors: Delgado Dávila Tamara , Tortoledo Rodríguez María 
Published: July 2021

Introducción: El cáncer de mama afecta cada vez más a las mujeres a nivel mundial. Los tipos de tratamiento quirúrgico y quimioterápico han evolucionado, consecuentemente es necesaria la correcta evaluación del tumor primario y los ganglios linfáticos implicados por ser un importante factor pronóstico y tratamiento. La técnica de ganglio centinela evalúa al primer ganglio en recibir el drenaje linfático del tumor.
Métodos: el objetivo fue determinar el impacto en pacientes con cáncer de mama en un estudio cuantitativo, observacional no experimental, correlacional de recolección retrospectiva, de tipo cohorte histórico. Se recuperó 153 pacientes en dos grupos de estudio, los que se sometieron a la técnica de ganglio centinela y los que se realizaron linfadenectomía axilar.
Resultados: el tipo histológico de cáncer de mama más frecuente fue el ductal infiltrante de grado histológico 2, un 76.4% y 73.6% de pacientes tuvieron receptores de estrógeno y progesterona positivo respectivamente mientras el receptor 2 de factor de crecimiento epidérmico humano fue positivo en 16.9%. La mediana del número de ganglios metastásicos fue semejante en los dos grupos, no así el número de ganglios libres 3 vs. 14 respectivamente (P < 0.001). En el estudio se evidenció morbilidad en 23.1% de pacientes que se biopsiaron el Ganglio Centinela, en contraste con 45.5% de en quienes no se efectuó dicho procedimiento (P = 0.025), la morbilidad más frecuentemente asociada fue el edema de la extremidad (27%).
Conclusiones: se demostró que la linfadenectomía expone tres veces a desarrollar morbilidades en comparación con la técnica de ganglio centinela.
MiR-92b-3p Inhibits Proliferation of HER2-Positive Breast Cancer Cell by Targeting circCDYL
Authors: Liang Gehao , Ling Yun , Lin Qun , Shi Yu , Luo Qing , Cen Yinghuan , Mehrpour Maryam , Hamai Ahmed , Li Jun , Gong Chang 
Published: July 2021

ObjectivesCircular RNA (circRNA) is a novel class of RNA, which exhibits powerful biological function in regulating cellular fate of various tumors. Previously, we had demonstrated that over-expression of circRNA circCDYL promoted progression of HER2-negative (HER2–) breast cancer via miR-1275-ULK1/ATG7-autophagic axis. However, the role of circCDYL in HER2-positive (HER2+) breast cancer, in particular its role in modulating cell proliferation, one of the most important characteristics of cellular fate, is unclear.Materials and methodsqRT-PCR and in situ hybridization analyses were performed to examine the expression of circCDYL and miR-92b-3p in breast cancer tissues or cell lines. The biological function of circCDYL and miR-92b-3p were assessed by plate colony formation and cell viability assays and orthotopic animal models. In mechanistic study, circRNAs pull-down, RNA immunoprecipitation, dual luciferase report, western blot, immunohistochemical and immunofluorescence staining assays were performed.ResultsCircCDYL was high-expressed in HER2+ breast cancer tissue, similar with that in HER2– breast cancer tissue. Silencing HER2 gene had no effect on expression of circCDYL in HER2+ breast cancer cells. Over-expression of circCDYL promoted proliferation of HER2+ breast cancer cells but not through miR-1275-ULK1/ATG7-autophagic axis. CircRNA pull down and miRNA deep-sequencing demonstrated the binding of miR-92b-3p and circCDYL. Interestingly, circCDYL did not act as miR-92b-3p sponge, but was degraded in miR-92b-3p-dependent silencing manner. Clinically, expression of circCDYL and miR-92b-3p was associated with clinical outcome of HER2+ breast cancer patients.ConclusionMiR-92b-3p-dependent cleavage of circCDYL was an essential mechanism in regulating cell proliferation of HER2+ breast cancer cells. CircCDYL was proved to be a potential therapeutic target for HER2+ breast cancer, and both circCDYL and miR-92b-3p might be potential biomarkers in predicting clinical outcome of HER2+ breast cancer patients.
Hotspots, Frontiers, and Emerging Trends of Superabsorbent Polymer Research: A Comprehensive Review
Authors: Yang Minmin , Wu Jihuai , Graham Geoffrey M. , Lin Jianming , Huang Miaoliang 
Published: July 2021

Superabsorbent polymer (SAP) is a kind of functional macromolecule with super-high water absorption and retention properties, which attracts extensive research and has wide application, especially in the areas of hygiene and agriculture. With reference to the Web of Science database, the SAP research literature from 2000 to 2019 is reviewed both quantitatively and qualitatively. By examining research hotspots, top research clusters, the most influential works, the representative frontier literature, and key emerging research trends, a visual panorama of the continuously and significantly increasing SAP research over the past 2 decades was presented, and issues behind the sharp increase in the literature were discovered. The findings are as follows. The top ten keywords/hotspots headed by hydrogel highlight the academic attention on SAP properties and composites. The top ten research themes headed by clay-based composites which boast the longest duration and the strongest impact have revealed the academic preference for application rather than theoretical study. Academically influential scholars and research studies have been acknowledged, and the Wu group was at the forefront of the research; however, more statistically significant works have been less detected in the last 10 years despite the sharper increase in publications. Hydrogel, internal curing, and aerogel are both current advances and future directions.
Submarine Groundwater Discharge From Non-Tidal Coastal Peatlands Along the Baltic Sea
Authors: Racasa Erwin Don , Lennartz Bernd , Toro Miriam , Janssen Manon 
Published: July 2021

Submarine groundwater discharge (SGD) is an important pathway for water and materials within the land-ocean transition zone that can impact coastal environments and marine life. Although research from sandy shorelines has rapidly advanced in recent years, there is very little understanding of coastal areas characterized by a low hydraulic conductivity, such as carbon-rich coastal peatlands. The objective of this study was to determine the magnitude and location of terrestrial SGD to be expected from a non-tidal low-lying coastal peatland located along the Baltic Sea and to understand the controlling factors using numerical modeling. We employed the HYDRUS-2D modeling package to simulate water movement under steady-state conditions in a transect that extends from the dune dike-separated rewetted fen to the shallow sea. Soil physical properties, hydraulic gradients, geological stratifications, and topography were varied to depict the range of properties encountered in coastal peatlands. Our results show that terrestrial SGD occurs at the study site at a flux of 0.080 m2 d−1, with seepage rates of 1.05 cm d−1 (upper discharge region) and 0.16 cm d−1 (lower discharge region above submerged peat layer). These calculated seepage rates compare to observations from other wetland environments and SGD sites in the Baltic Sea. The groundwater originates mainly from the dune dike—recharged by precipitation and infiltration from ponded peatland surface water—and to a lesser extent from the sand aquifer. The scenario simulations yielded a range of potential SGD fluxes of 0.008–0.293 m2 d−1. They revealed that the location of terrestrial SGD is determined by the barrier function of the peat layer extending under the sea. However, it has little impact on volume flux as most SGD occurs near the shoreline. Magnitude of SGD is mainly driven by hydraulic gradient and the hydraulic conductivity of peat and beach/dune sands. Anisotropy in the horizontal direction, aquifer and peat thickness, and peatland elevation have little impacts on SGD. We conclude that SGD is most probable from coastal peatlands with high water levels, large Ks and/or a dune dike or belt, which could be an essential source for carbon and other materials via the SGD pathway.
Seminal Plasma Lipidomics Profiling to Identify Signatures of Kallmann Syndrome
Authors: Li Xiaogang , Wang Xi , Li Haolong , Li Yongzhe , Guo Ye 
Published: July 2021

BackgroundKallmann syndrome (KS) is a rare developmental disorder. Our previous metabolomics work showed substantial changes in linoleic acid and glycerophospholipid metabolism in KS. Here, we performed targeted lipidomics to further identify the differential lipid species in KS.MethodsTwenty-one patients with KS (treatment group) and twenty-two age-matched healthy controls (HC, control group) were enrolled. Seminal plasma samples and medical records were collected. Targeted lipidomics analysis of these samples was performed using ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS).ResultsLipidomics profiling of patients with KS and the HCs showed clear separation in the orthogonal projections to latent structures-discriminant analysis (OPLS-DA). There were many differential lipids identified, with the main differential lipid species being triacylglycerols (TAGs), phosphatidylcholines (PCs) and phosphatidylethanolamine (PE).ConclusionsThe lipidomics profile of patients with KS changed. It was also determined that TAGs, PCs and PE are promising biomarkers for KS diagnosis. To our knowledge, this is the first report to analyze lipidomics in men with Kallmann syndrome.