bluuebunny/crossref_metadata_2025_split huggingface dataset:
La figure divine de Wei Huacun 魏華存 dans le taoïsme Shangqing au VIIIe siècle : la place du culte et la question du genre dans la pratique spirituelle
Authors: Boutonnet Olivier 
Published: December 2021

Résumé
Selon la tradition, Wei Huacun (251-334), ou plutôt sa figure déifiée, la Dame Wei du pic du Sud, est la matriarche fondatrice du courant taoïste de la Pureté supérieure, ou Shangqing, apparu au cours de la seconde moitié du IVe siècle de notre ère. Si l’ historicité de ce mouvement à la fin des Six Dynasties (220-589) a été abondamment étudiée, son évolution postérieure, en particulier sous les Tang (618-907), laisse encore apparaître des zones d’ ombre. L’ étude de la figure divine de la Dame Wei, à la fois sur le plan de son culte et sur celui des exercices spirituels auxquels elle était associée, contribue à mieux cerner les contours de cette tradition vivante. Elle permet également d’ affiner notre vision de sa praxis telle que les taoïstes, hommes et femmes, pouvaient se l’ approprier dans leur propre religiosité vis-à-vis de la religion instituée.
International Cooperation under the United Nations Convention against Transnational Organized Crime
Authors: Schloenhardt Andreas 
Published: December 2021

Abstract
This article examines the international cooperation provisions under the United Nations Convention against Transnational Organized Crime and their practical application in reported cases. It explores the circumstances in which States Parties have used or attempted to use the Convention as a legal basis for extradition, mutual legal assistance, transfer of sentenced persons, transfer of criminal proceedings, joint investigations, or other forms of international cooperation. The article seeks to provide a better understanding of the opportunities offered by the international cooperation provisions, and the challenges and obstacles faced by States Parties requesting cooperation or being requested to provide cooperation under the Convention.
The Smuggling Protocol and the Criminalization of Humanitarian Activities at Sea
Authors: Salvadego Laura 
Published: December 2021

Abstract
This paper focuses on some recent events of criminalization of humanitarian activities at sea in Italy, and precisely the Open Arms and the Sea Watch 3 cases. It is stated that criminalization of humanitarian activities at sea is largely due to a substantial ‘implementation gap’ between the Smuggling Protocol and the current EU legal framework on people smuggling, that is the so-called ‘Facilitators’ Package’ of 2002. It is further contended that legal certainty requirements make legislative reform necessary in Italy to prevent the criminalization of humanitarian activities at sea.
Enhancing Sustainable Consumption in China: A Seafood Example
Authors: He Juan 
Published: December 2021

Abstract
In recent years, market surveys on sustainable seafood consumption have analysed Chinese people’s willingness to purchase ecolabelled seafood produced and imported into China. Endogenous and exogenous determinants are thereby unveiled to explore Chinese consumers’ sustainability consciousness, purchasing decisions, and the means of bridging the divide. This article builds upon and adds to these empirical findings with a market-based and information lens. It draws inspiration from analysing the growing interest of younger and middle-class consumers in acquiring seafood information; integrative sourcing and marketing strategies of intermediary businesses to deliver such information; and awakening of public regulators to the imperative of realizing the right to information of less-informed parties. Instead of segregating these stakeholders along a linear supply chain, the study emphasizes the deepening of a consumer-centric information network underpinned by supply chain transparency and traceability. It thus aims to inform a steady shift from a production-oriented to a consumer-oriented seafood management paradigm through systematic reforms of China’s consumer law. To encourage and empower sustainable consumption, the ‘consumer’ notion needs proper broadening and consumers’ right to know should be recognized as a judicial and self-contained legal entitlement with enforcement safeguards.
Agency, Responsibility, and Actor Positioning In Courtroom Narratives
Authors: Chaemsaithong Krisda 
Published: December 2021

Abstract
Viewing language as a system consisting of grammatical resources for meaning making, this study explores how agency and responsibility are attributed in legal narratives through the lens of transitivity. Drawing upon the opening address of three American trials, the quantitative and qualitative findings indicate that agency and blameworthiness of the individuals on trial are discursively negotiated through starkly different grammatical choices, so that polarized positionings of the same social actors and events are accomplished for the audience. It is argued that such manipulation of grammatical resources exhibits subjective intervention on the part of the presenter and constitutes a prime mechanism of inference and attitudinal evocation for the jurors. In effect, the opening statement, which is in principle intended to be merely informative, becomes not only argumentative but also evaluative.
Thai elf Users’ Characteristics of Relative Clauses
Authors: Timyam Napasri 
Published: December 2021

Abstract
To build up the empirical description of elf’s morphosyntactic system, this study examines Thai elf users’ characteristics of relative clauses and analyses the causes underlying their use of the construction. Data were taken from the writing of 116 advanced and upper-intermediate English majors at a university in Bangkok. The results indicated that Thai elf users’ relative clauses exhibit preferences for unmarked and explicit structures. Both linguistic and functional causes are responsible for their production of the construction: they form relative clauses full of basic and transparent structures in order to ensure simple and successful communication. The overall results reveal the nature of elf communication. Although Thai elf users’ relative clauses are associated with some specific patterns, their use of this grammatical construction is governed by general linguistic processes which have been found to operate in the interactions of many groups of elf speakers, especially at the phonological and pragmatic levels.
Community participation as a predictor of depressive symptoms among individuals with serious mental illnesses
Authors: Nagata Shinichi , McCormick Bryan , Brusilovskiy Eugene , Salzer Mark S 
Published: December 2021

Background: People with serious mental illnesses have elevated levels of depressive symptoms. Limited engagement in meaningful activities, such as work, social interactions, volunteering, and participation in faith, are one plausible explanation for this. Increased community participation over time may be associated with decreased depressive symptoms. Aim: Examine whether an increase in participation over time predicts a decrease in depression after controlling for depression at the baseline. Methods: Participants were 183 adults with schizophrenia spectrum, bipolar disorder, or major depressive disorder who completed the Hopkins Symptom Index – Depression subscale and the Temple University Community Participation Measure. Participants completed these measures at baseline and either a 12- or 24-month follow-up timepoint. Multiple regression analyses were conducted with the depression score as a dependent variable and changes in community participation as a predictor variable. Demographics, baseline depression score, and time interval between baseline and last observation were entered as control variables. Results: Endorsing more activities as important, participating in more important areas that are important, and participating ‘enough’ in more important areas over time were each significant predictors of decreases in depression. Conclusion: These findings enhance the connection between community participation and depression and suggest that a focus on participation may be important in terms of boosting both community functioning and treatment goals.
Clinical Application of Low-Temperature Plasma Radiofrequency in the Treatment of Hemangioma in Nasal Cavity, Pharynx and Larynx
Authors: Long Xiaobo , Li Zhiyong , Liu Yang , Zhen Hongtao 
Published: December 2021

Objective Hemangioma is a common benign tumor in the head and neck. The therapeutic effect by conventional treatment was not very satisfactory. The purpose of this study is to explore the surgical strategy of low-temperature plasma radiofrequency in the treatment of hemangioma located in the nasal cavity, pharynx, and larynx. Methods The clinical data of 29 cases with hemangioma in nasal cavity, pharynx, and larynx treated by low-temperature plasma radiofrequency ablation were retrospectively analyzed. The strategy of ablation before resection was performed for 16 cases of nasal capillary hemangioma. The other 13 cases of cavernous hemangioma in the pharynx and larynx were treated by the strategy of direct ablation. Results All 29 patients underwent a successful operation with minimal intraoperative bleeding and no postoperative bleeding complications. There was no nasal septum perforation, dyspnea, dysphagia, dysphonia, or other complications. The patients were followed up for more than 3 years without recurrence. Conclusion Low-temperature plasma radiofrequency is a practical, minimally invasive, and accurate method for treating hemangiomas in the nasal cavity, pharynx, and larynx. For capillary hemangiomas, the strategy of ablation before resection may be an effective way to reduce bleeding, and for cavernous hemangiomas, the strategy of direct ablation is a simple and efficient method.
Influencing factors of depressive symptoms in patients with malignant tumour
Authors: Wang Dongmei , He Nana , Liu Yuwu , Pang Rui , Dilixiati Meikereayi , Wumaier Ainiwaer 
Published: December 2021

Objective To assess the influencing factors of depressive symptoms in malignant tumour patients. Methods Participants were 2079 inpatients with malignant tumour (1291: depressive symptoms; 788 no depressive symptoms). Univariable and multivariable logistic regression were used to evaluate sociodemographic and clinical factors influencing depressive symptoms. Results Risk factors were family income ≤5000 yuan (odds ratio [OR]: 4.966, 95% confidence interval [CI]: 2.938–8.395) and 5001–10,000 yuan (OR: 3.111, 95% CI: 1.840–5.260); Karnofsky Performance Status of 70 (OR: 2.783, 95% CI: 1.281–6.042) and 80 (OR: 1.834, 95% CI: 1.139–2.953); disease course ≤1 year; palliative treatment (OR: 2.288, 95% CI: 1.292–4.055); progressive disease (OR: 1.876, 95% CI: 1.284–2.739); pain (OR: 1.973, 95% CI: 1.555–2.505); cancer type: lung (OR: 3.199, 95% CI: 1.938–5.279), oesophagus (OR: 3.288, 95% CI: 1.673–6.464), cervix (OR: 1.542, 95% CI: 1.056–2.253) and partial knowledge of disease condition (OR: 2.366, 95% CI: 1.653–3.385). Return to work (OR: 0.503, 95% CI: 0.348–0.727) and physical exercise (OR: 0.437, 95% CI: 0.347–0.551) were protective against depressive symptoms. Conclusions Several factors affected depressive symptoms in malignant tumour patients, including income, disease type and course, palliative treatment, return to work and physical exercise.
Healthcare utilization among persons living with HIV in Manitoba, Canada, prior to HIV diagnosis: A case-control analysis
Authors: Shaw Souradet Y , Ireland Laurie , McClarty Leigh M , Loeppky Carla , Bullard Jared , Van Caeseele Paul , Keynan Yoav , Kasper Ken , Moses Stephen , Blanchard James F , Becker Marissa L 
Published: December 2021

Background Understanding care patterns of persons living with HIV prior to diagnosis can inform prevention opportunities, earlier diagnosis, and engagement strategies. We examined healthcare utilization among HIV-positive individuals and compared them to HIV-negative controls. Methods Data were from a retrospective cohort from Manitoba, Canada. Participants included individuals living with HIV presenting to care between 2007 and 2011, and HIV-negative controls, matched (1:5) by age, sex, and region. Data from population-based administrative databases included physician visits, hospitalizations, drug dispensation, and chlamydia and gonorrhea testing. Diagnoses associated with physician visits were classified according to International Classification of Diseases chapters. Conditional logistic regression models were used to compare cases/controls, with adjusted odds ratios (AORs) and their 95% confidence intervals (95% CI) reported. Results A total of 193 cases and 965 controls were included. Physician visits and hospitalizations were higher for cases, compared to controls. In the 2 years prior to case date, cases were more likely to be diagnosed with “blood disorders” (AOR: 4.2, 95% CI: 2.0–9.0), be treated for mood disorders (AOR: 2.4, 95% CI: 1.6–3.4), and to have 1+ visits to a hospital (AOR: 2.2, 95% CI: 1.4–3.6). Conclusion Opportunities exist for prevention, screening, and earlier diagnosis. There is a need for better integration of healthcare services with public health.
Electroacupuncture altered expression of microRNAs in Stat5 knockout obese mice
Authors: Hong Hao , Xu Hou-Xi , Meng Jian-Zhong , Zhu Bing-Mei 
Published: December 2021

Background: Increasing evidence shows that miRNAs contribute to the establishment and development of obesity by affecting many biological and pathological processes, such as adipocyte differentiation, hepatic lipid metabolism, insulin resistance, and neurological regulation of obesity. As a clinical intervention approach, acupuncture has been shown to be effective in the treatment of obesity and other metabolic diseases. Our previous whole genome study in central nervous system (CNS)-specific Stat5 knockout (NKO) obese mice found that electroacupuncture (EA) could reduce body weight and promote white browning. Objective: To clarify the effect of EA on miRNAs and understand how it regulates gene expression. Methods: Twelve-week-old male Stat5NKO mice with body weight 20% greater than that of Stat5fl/fl (control) mice were divided into a Stat5NKO (model) group and EA-treated Stat5NKO + EA group. A cohort of Stat5fl/fl mice of the same age were included as the control group. EA was administered under isoflurane anesthesia at unilateral ST36 and ST44 daily (left and right sides were treated every other day), 6 times per week for a total of 4 weeks. The miRNA profile was generated and miRNA regulatory networks were analyzed in the Stat5 nestin-cre mice before and after EA treatment. Autophagy-related proteins in adipocytes were detected after over-expression of miR27a. Results: EA altered abnormal miRNA expression, including miRNA27a expression, and reduced the autophagy-related proteins ATG5 and ATG12. Conclusion: We found that EA could regulate miRNA27a-mediated autophagy-related proteins and promote white fat browning, which may contribute to weight loss. To our knowledge, this is the first report of miRNAs potentially driving the effect of EA on white fat browning through the autophagy process.
Electroacupuncture promotes microglial M2 polarization in ischemic stroke via annexin A1
Authors: Zou Jing , Huang Guo-fu , Xia Qian , Li Xing , Shi Jing , Sun Ning 
Published: December 2021

Background: Neuroinflammation is the leading cause of neurological sequelae in ischemic stroke. Recently, we reported that the anti-inflammatory mediator annexin A1 (ANXA1) favored microglial M2 polarization in brain injury. The purpose of this study was to investigate electroacupuncture (EA) treatment and its potentially ANXA1-mediated anti-inflammatory effects in the middle cerebral artery occlusion/reperfusion (MCAO/R) mouse model of stroke. Methods: Treatment with EA consisted of dense-sparse frequencies (alternating 4 Hz sparse waves for 1.5 s and 16 Hz dense waves for 1.5 s) at CV24 and GV26. Intracerebroventricular (ICV) injection of Boc-2 (5 µM) or short hairpin RNA (sh)ANXA1 (2 µL) 3 days before EA was performed to block the effects of ANXA1. Results: EA pretreatment enhanced expression of ANXA1 and its receptor, formyl peptide receptor (FPR), when compared to MCAO/R alone. EA treatment also rescued MCAO/R-induced deficits in neurological performance, and learning and memory, and reduced infarct volume. Double immunofluorescent labeling showed that EA prevented MCAO/R-induced changes in microglial activation and morphology. EA also reduced the release of pro-inflammatory cytokines, such as interleukin (IL)-1β, inducible nitric oxide synthase (iNOS) and tumor necrosis factor (TNF)-α, while increasing the release of anti-inflammatory cytokines, such as arginase-1 (Arg-1) and brain-derived neurotrophic factor (BDNF). All EA-induced effects were either partially or completely prevented by prior administration of FPR antagonist Boc-2 or shANXA1. Conclusion: The current study provides strong evidence that EA treatment has protective effects against ischemic stroke in the MCAO/R mouse model and that the mechanism likely involves the promotion of M2 polarization in microglia via ANXA1.
Influence of geometric parameters on free vibration behavior of an aluminum honeycomb core sandwich beam using experimentally validated finite element models
Authors: Pourriahi Vahid , Heidari-Rarani Mohammad , Torabpour Isfahani Amir 
Published: December 2021

The hexagonal honeycomb core sandwich panels used in the satellite structure are subjected to severe vibration during launch. Therefore, the amounts of natural frequencies of these panels are of great importance for design engineers. Three-dimensional finite element modeling of the core considering all geometric parameters (i.e., a high-fidelity model) to achieve accurate results is not cost-effective. The honeycomb core is traditionally equivalent to a homogenized continuum core (i.e., a low-fidelity model) using simple analytical relations with ignoring the adhesive layer at the double cell-walls and radius of inclined cell-wall curvature. In this study, analytical formulations are first presented for the prediction of the equivalent elastic properties of a hexagonal aluminum honeycomb with considering all geometric parameters including adhesive layer thickness, cell-wall thickness, inclined cell-wall length, radius of inclined cell-wall curvature at the intersection, internal cell-wall angle, and honeycomb height. Then, two aluminum honeycomb core sandwich beams with free-free boundary conditions are modeled and analyzed in Abaqus finite element software, one with 3D high-fidelity core and the other with 3D low-fidelity core. In order to validate the results of the equivalent model, the modal analysis test was performed and the experimental natural frequencies were compared. The obtained results show a good agreement between the 3D low-fidelity and high-fidelity finite element models and experimental results. In addition, the influence of the above-mentioned geometric parameters has been investigated on the natural frequencies of a sandwich beam. [Formula: see text]
Clarifying selection bias in cluster randomized trials
Authors: Li Fan , Tian Zizhong , Bobb Jennifer , Papadogeorgou Georgia , Li Fan 
Published: December 2021

Background In cluster randomized trials, patients are typically recruited after clusters are randomized, and the recruiters and patients may not be blinded to the assignment. This often leads to differential recruitment and consequently systematic differences in baseline characteristics of the recruited patients between intervention and control arms, inducing post-randomization selection bias. We aim to rigorously define causal estimands in the presence of selection bias. We elucidate the conditions under which standard covariate adjustment methods can validly estimate these estimands. We further discuss the additional data and assumptions necessary for estimating causal effects when such conditions are not met. Methods Adopting the principal stratification framework in causal inference, we clarify there are two average treatment effect (ATE) estimands in cluster randomized trials: one for the overall population and one for the recruited population. We derive analytical formula of the two estimands in terms of principal-stratum-specific causal effects. Furthermore, using simulation studies, we assess the empirical performance of the multivariable regression adjustment method under different data generating processes leading to selection bias. Results When treatment effects are heterogeneous across principal strata, the average treatment effect on the overall population generally differs from the average treatment effect on the recruited population. A naïve intention-to-treat analysis of the recruited sample leads to biased estimates of both average treatment effects. In the presence of post-randomization selection and without additional data on the non-recruited subjects, the average treatment effect on the recruited population is estimable only when the treatment effects are homogeneous between principal strata, and the average treatment effect on the overall population is generally not estimable. The extent to which covariate adjustment can remove selection bias depends on the degree of effect heterogeneity across principal strata. Conclusion There is a need and opportunity to improve the analysis of cluster randomized trials that are subject to post-randomization selection bias. For studies prone to selection bias, it is important to explicitly specify the target population that the causal estimands are defined on and adopt design and estimation strategies accordingly. To draw valid inferences about treatment effects, investigators should (1) assess the possibility of heterogeneous treatment effects, and (2) consider collecting data on covariates that are predictive of the recruitment process, and on the non-recruited population from external sources such as electronic health records.
Cartilage Matrix Degeneration Occurs within the First Year after ACLR and Is Associated with Impaired Clinical Outcome
Authors: Williams Ashley A. , Deadwiler Brittney C. , Dragoo Jason L. , Chu Constance R. 
Published: December 2021

Objective Anterior cruciate ligament reconstruction (ACLR) has not been shown to decrease the risk for development of post-traumatic osteoarthritis. Magnetic resonance imaging (MRI) T2 mapping can be used to assess cartilage compositional changes. This study tests whether (1) worse cartilage arthroscopic status at ACLR is reflected by higher cartilage T2 values in matched study regions 6 weeks and 1 year after ACLR, and (2) increasing cartilage T2 values between 6 weeks and 1 year after ACLR are associated with worsening patient-reported outcomes. Design Twenty-two participants with ACLR and 26 controls underwent 3T MRI. T2 values in medial and lateral femoral and tibial cartilage were measured at 6 weeks and 1 year after ACLR and compared with arthroscopic grades, Knee injury and Osteoarthritis Outcome Scores (KOOS), and control T2 values. Results Most (59%-86%) cartilage study regions examined by arthroscopy demonstrated intact articular surfaces. Average T2 value increased in 3 of 4 study regions between 6 weeks and 1 year after ACLR ( P = .001-.011). T2 value increased ( P < .013) even for participants whose cartilage had intact articular surfaces at ACLR. Participants with ACLR who showed greater increases in cartilage T2 values had less improvement to KOOS Quality of Life ( P = .009, ρ = −0.62). Discussion Cartilage status assessed arthroscopically at ACLR and by MRI T2 maps 6 weeks later was healthier than cartilage status assessed by MRI T2 maps at 1-year follow-up. Progressive T2 elevations were observed over the first year after ACLR even in patients with arthroscopically intact cartilage at the time of surgery and were associated with reduced improvement in knee quality of life suggesting preosteoarthritis.