bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improvement of interfacial interactions in CF/PEEK composites by an s‐PSF/graphene oxide compound sizing agent
Authors: Ren Tianning , Zhu Guangming , Hou Xiao , Li Ben , Hao Yujia 
Published: July 2021

AbstractThe interfacial interactions of carbon fiber (CF)‐reinforced polymer composites is a key factor affecting the overall performance of the material. In this work, we prepared a sulfonated poly(ether sulfone)–graphene oxide mixed sizing agent to modify the interface of CF/PEEK composites and improve the interfacial properties between the PEEK matrix and CF. Results showed that the mechanical and interfacial properties of CF/PEEK composites are improved by the sizing agent. Specifically, the flexural strength, flexural modulus and interlaminar shear strength of the materials reached 847.29 MPa, 63.77 GPa, and 73.17 MPa, respectively. Scanning electron microscopy confirmed markedly improved adhesion between the resin matrix and fibers. This work provides a simple and effective method for the preparation of high‐performance CF/PEEK composites, which can improve the performance of composites without degrading the mechanical property of pristine CF.
Induction of Interferon‐γ and Tissue Inflammation by Overexpression of Eosinophil Cationic Protein in T Cells and Exosomes
Authors: Chuang Huai‐Chia , Chen Ming‐Han , Chen Yi‐Ming , Ciou Yi‐Ru , Hsueh Chia‐Hsin , Tsai Ching‐Yi , Tan Tse‐Hua 
Published: July 2021

ObjectiveT cells play a critical role in the pathogenesis of systemic lupus erythematosus (SLE). Serum‐derived exosomes are increased in SLE patients and are correlated with disease severity. This study was undertaken to investigate whether T cell–derived exosomal proteins play a role in SLE pathogenesis.MethodsWe characterized proteins in T cell–derived exosomes from SLE patients and healthy controls by MACSPlex exosome analysis and proteomics. To study the potential pathogenic functions of the exosomal protein identified, we generated and characterized T cell–specific transgenic mice that overexpressed that protein in T cells.ResultsWe identified eosinophil cationic protein (ECP, also called human RNase III) as overexpressed in SLE T cell–derived exosomes. T cell–specific ECP–transgenic mice (n = 5 per group) displayed early induction of serum interferon‐γ (IFNγ) levels (P = 0.062) and inflammation of multiple tissue types. Older T cell–specific ECP–transgenic mice (n = 3 per group) also displayed an increase in follicular helper T cell and plasma B cell numbers, and in autoantibody levels (P < 0.01). Single‐cell RNA sequencing showed the induction of IFNγ messenger RNA (P = 2.2 × 10‐13) and inflammatory pathways in ECP‐transgenic mouse T cells. Notably, adoptively transferred ECP‐containing exosomes stimulated serum autoantibody levels (P < 0.01) and tissue IFNγ levels in the recipient mice (n = 3 per group). The transferred exosomes infiltrated into multiple tissues of the recipient mice, resulting in hepatitis, nephritis, and arthritis.ConclusionOur findings indicate that ECP overexpression in T cells or T cell–derived exosomes may be a biomarker and pathogenic factor for nephritis, hepatitis, and arthritis associated with SLE.
International perspectives on suboptimal patient‐reported outcome trial design and reporting in cancer clinical trials: A qualitative study
Authors: Retzer Ameeta , Calvert Melanie , Ahmed Khaled , Keeley Thomas , Armes Jo , Brown Julia M. , Calman Lynn , Gavin Anna , Glaser Adam W. , Greenfield Diana M. , Lanceley Anne , Taylor Rachel M. , Velikova Galina , Brundage Michael , Efficace Fabio , Mercieca‐Bebber Rebecca , King Madeleine T. , Kyte Derek 
Published: July 2021

AbstractPurposeEvidence suggests that the patient‐reported outcome (PRO) content of cancer trial protocols is frequently inadequate and non‐reporting of PRO findings is widespread. This qualitative study examined the factors influencing suboptimal PRO protocol content, implementation, and reporting, and use of PRO data during clinical interactions.MethodsSemi‐structured interviews were conducted with four stakeholder groups: (1) trialists and chief investigators; (2) people with lived experience of cancer; (3) international experts in PRO cancer trial design; (4) journal editors, funding panelists, and regulatory agencies. Data were analyzed using directed thematic analysis with an iterative coding frame.ResultsForty‐four interviews were undertaken. Several factors were identified that could influenced effective integration of PROs into trials and subsequent findings. Participants described (1) late inclusion of PROs in trial design; (2) PROs being considered a lower priority outcome compared to survival; (3) trialists’ reluctance to collect or report PROs due to participant burden, missing data, and perceived reticence of journals to publish; (4) lack of staff training. Strategies to address these included training research personnel and improved communication with site staff and patients regarding the value of PROs. Examples of good practice were identified.ConclusionMisconceptions relating to PRO methodology and its use may undermine their planning, collection, and reporting. There is a role for funding, regulatory, methodological, and journalistic institutions to address perceptions around the value of PROs, their position within the trial outcomes hierarchy, that PRO training and guidance is available, signposted, and readily accessible, with accompanying measures to ensure compliance with international best practice guidelines.
Worsening renal function after transcatheter aortic valve replacement: Infrequent but deleterious
Authors: Elgendy Islam Y. , Jneid Hani 
Published: July 2021

Key Points
A significant proportion of patients undergoing transcatheter aortic valve replacement (TAVR) has underlying chronic kidney disease (CKD).
Approximately 15% of patients with CKD develop worsening renal function at 3–6 months after TAVR. Worsening renal function at 3–6 months is independently associated with long‐term mortality.
Acute kidney injury (AKI) and peri‐procedural blood transfusion of ≥4 units are independently associated with worsening renal function at 3–6 months. Incorporating strategies to mitigate the hazards of AKI and major bleeding in this high‐risk cohort is imperative.
Mesoporous SiO2‐Encapsulated Nano‐Co3O4 Catalyst for Efficient CO Oxidation
Authors: Gao Zhongnan , Zhao Dongyue , Cheng Qingpeng , Zhao Dejian , Yang Yuexi , Tian Ye , Ding Tong , Song Song , Guo Lihong , Li Xingang 
Published: July 2021

AbstractTo meet the increasing demand for efficient and durable catalysts for exhaust aftertreatment system, a mesoporous SiO2‐encapsulated nano‐Co3O4 catalyst was synthesized, which possesses a unique pitaya‐like structure with high CO oxidation activity and thermal stability. Though the silica matrix is inert, the encapsulated Co3O4 exhibits increased oxygen storage capacity, enhanced CO2 desorption behavior and high lattice oxygen reactivity. Additionally, the SiO2‐encapsulated Co3O4 catalyst can be effectively regenerated rather than the supported Co3O4/SiO2 and pure Co3O4. The kinetic results demonstrate that the L−H mechanism is followed over the pure Co3O4 nanoparticles catalyst, while the CO oxidation over the silica‐supported Co3O4 catalysts obey to both L−H and MVK mechanism. The encapsulation structure of the as‐prepared catalyst can effectively restrain the aggregation of Co3O4 during high temperature operations and improves the utilization efficiency of cobalt resources, as well, which would be suitable for practical applications.
Dual‐Carbon Confined SnP2O7 with Enhanced Pseudocapacitances for Improved Li/Na‐Ion Batteries
Authors: Guo Xinzhu , Wan Zhengwei , Wei Di , Zeng Xiaomin , Li Zeheng , Jiang Wei , Wang Hongxun , Ling Min , Li Hui , Liang Chengdu 
Published: July 2021

AbstractTin‐based materials have obtained much attention in lithium‐ion batteries (LIBs) due to high specific capacity. However, the large volume change and poor electroconductivity hinder their further practical application. Herein, a C18N12 (CN)‐wired amorphous carbon coated pyrophosphate tin (SnP2O7@C) ultrafine nanoparticles composite (SnP2O7@C/CN) is prepared by solvothermal‐calcination with phytic acid (PA) as phosphorus and carbon sources simultaneously. Ultrafine‐nanocrystallization and dual‐carbon doping enhances the pseudocapacitance of SnP2O7@C/CN and thus, exhibit good electrochemical performance and high lithium/sodium storage efficiency. As anode of LIBs, the SnP2O7@C/CN exhibits a superior reversible capacity of 557.3 mAh/g after 100 cycles at a current density of 0.2 A/g and a conspicuous cyclability of 352.3 mAh/g after 800 cycles at 1 A/g. For sodium‐ion batteries (SIBs), the stable discharge capacity of SnP2O7@C/CN electrode is 91.5 mAh/g after 800 cycles at a high current density of 2 A/g. This strategy can increase active sites, provide large electrolyte/electrode contact area, and improve electroconductivity. Moreover, SnP2O7@C/CN electrode provides a buffer space for structural strains caused by volume changes during charging and discharging.
Hardware Trojan detection for lightweight ciphers implemented on field‐programmable gate arrays using the replay algorithm
Authors: Abed Sa'ed , Mohd Bassam J. , Hayajneh Thaier , Alshayeji Mohammad H. 
Published: July 2021

SummaryHardware Trojans (HTs) are malicious and intentional modification of the hardware design, embedded by an adversary to leak sensitive data, modify functionality, or cause malfunction. Lightweight ciphers are designed for resource‐constrained devices (RCDs) to balance resources and security, but often targeted by HTs. This work aims to create a trusted lightweight cipher design and detect complex sequential HTs using a runtime monitoring method with minimal resource overhead. The novelty of the approach is that it combines full or partial temporal redundancy, resource minimization, and runtime monitoring. The algorithm employs temporal redundancy, by executing a first run of the cipher, and then replays the cipher fully (ReplayN method) or partially (ReplayN/2 method). A mismatch indicates HT activity, and a third replay is executed to determine the correct results. The ReplayN/2 algorithm further optimizes time and energy by limiting replay to the second half of the cipher rounds. The proposed method is compared with other existing methods including triple modular redundancy (TMR), adapted triple modular redundancy (ATMR), and reverse‐function redundancy (RFR). All methods were implemented in field‐programmable gate array (FPGA) technology. Implementation performance metrics were measured and compared, including resource utilization (i.e., logical elements [LEs]), power, energy (E), and speed (i.e., Fmax). The results show that the proposed algorithm outperforms existing methods in most of the metrics. In terms of speed and area, the replay algorithm is faster by 24% and reduces total LEs by 42% when compared with existing methods. Regarding power, replay algorithm reduces power by 45% when compared with TMR and ATMR. With respect to energy, replay methods reduce energy by an average of 6% when compared with TMR and ATMR. The ReplayN/2 reduces energy by an average 15% when compared with TMR and ATMR. Based on the
(i.e., energy × area) metric, ReplayN/2 is the top performing method as it balances area and energy metrics. Using
metric, the replay methods are the best performing methods as they best balance area, energy, and speed. Also, based on
metric, the replay methods are the top performing methods.
The least‐square design of minimum‐order allpass‐based infinite impulse response multi‐notch filters
Authors: Krstić Ivan 
Published: July 2021

SummaryThe paper investigates the least‐square design of minimum‐order infinite impulse response multi‐notch filters. Monotonically decreasing nature of the stable allpass filter's phase response, characterizing the allpass‐based multi‐notch filter, along with the simple relation between coefficients and the phase response of the allpass filter, allows the formulation of the multi‐notch filter's magnitude response specifications as the linear equality constraints regarding the positions of notch, left‐ and right‐hand cutoff frequencies. Since the number of such constraints equals triple the number of notch frequencies, while the number of unknown filter coefficients equals double the number of notch frequencies, variable elimination is first performed to ensure that specifications regarding the notch frequencies positions are strictly satisfied. The remaining overdetermined system of linear equations is then solved in the least‐square sense, leading to the approximate satisfaction of left‐ and right‐hand cutoff frequencies positions. Proposed design method is also compared with some of the existing infinite impulse response multi‐notch filter design methods.
Serrated polyposis syndrome with multiple inverted lesions in the colon: Case report and elucidation of morphogenetic mechanism
Authors: Yoshikawa Chihiro , Koyama Fumikazu , Morita Kohei , Kuge Hiroyuki , Nakamoto Takayuki , Obara Shinsaku , Iwasa Yosuke , Kunishige Tomohiro , Ohbayashi Chiho , Sho Masayuki 
Published: July 2021

AbstractA 70‐year‐old man underwent surveillance colonoscopy following surgery for occlusive sigmoid colon cancer. The procedure revealed nine sessile serrated lesions (SSLs), including three inverted lesions. Endoscopic and surgical resections were performed. All nine lesions were confirmed pathologically as SSL, and the patient was diagnosed with serrated polyposis syndrome (SPS). Three inverted SSLs (iSSLs) showed endophytic growth without epithelial misplacement. Crypt analysis revealed that iSSL crypts were wider at the bottom than the opening, roughly resembling a frustoconical shape. Our results suggest that a horizontal arrangement of frustoconical crypts leads to hemispherical deformation of the muscularis mucosa, forming an inverted shape. This is the first report to reveal the morphogenesis of iSSLs from the shape of the crypt.
Design, simulation and analysis of a fast charging station for electric vehicles
Authors: Khalid Mohd , Ahmad Furkan , Panigrahi Bijya Ketan 
Published: July 2021

AbstractWith the advent of Electric Vehicles into existence, there is a need to develop a significantly charging infrastructure that will make electric cars more attractive and lead to higher adoption rates. In light of the increasing demand for EVs, there is a need to develop a fast‐charging station that cuts back on the charging time and hence overcome range anxiety. Fast charging stations are capable of reducing the charging duration by up to 30 min. By way of sustainable development and availability of secure energy, the focus of the paper is to develop the fast charging station of various Electric vehicles/Plug‐in Hybrid Electric vehicles as per the grid power supply and their worldwide implementation. In this paper, we have designed a system for the fast charging of electric vehicles in which we provide continuous feedback to the dc‐dc converter considering the battery SOC by using a battery pack control module and tuning the PI controller. To reduce the fluctuation in input supply, we have studied and implemented a cosine firing scheme based voltage regulator and electronic tap changer (ETC) out of which ETC provides a very promising solution. Further, the impact of charging with time on battery resistance has also been discussed.
Unfolding Birth Justice in Settler States
Authors: Ganapathy Sandhya 
Published: July 2021

AbstractThere is growing scholarly and public attention toward the stark racial disparities in birth outcomes in the US. To lower disparate rates of Indigenous and Black infant mortality rates and maternal mortality rates, public and elected officials have proposed extending comprehensive prenatal care and medical resources and addressing racial biases in healthcare delivery. These efforts aim to bring minoritized and marginalized peoples and communities “into the fold.” In this essay, I consider the potential dangers of such contemporary efforts by critically analyzing historical initiatives to address birth outcomes and reproductive health in Indigenous communities. By foregrounding settler colonial social orders and their links to settler capitalism, I show how historical efforts to bring Indigenous peoples “into the fold” jeopardized Indigenous birth and reproductive capacities, while also upholding heteropatriarchal notions of sexuality, family, and racial difference.
Gender imbalance in the genetic counseling profession: An Australasian perspective
Authors: Badman Stephanie 
Published: July 2021

AbstractGender imbalance exists in the genetic counseling profession, with approximately 95% of genetic counselors identifying as female. Genetic counseling programs in Australia have increased the proportion of male student enrolments in recent years, although this is yet to have an impact on gender balance in the profession more broadly. While significant resources have been allocated to improving female representation in traditionally male professions, there has not been a reciprocal movement of men into traditionally female professions. The lower status awarded to traditionally female roles creates a disincentive for men to choose non‐traditional career paths. Although genetic counselors have expertise in both genetics and counseling, the profession is viewed as a predominantly helping profession and therefore ‘women's work’. Men who work in traditionally female roles report role strain and stereotyping, which affect experiences at work and challenge personal identities. Male advantage is also documented, especially with respect to salary. There remains a lack of understanding of the effect of gender imbalance on aspects of patient care, genetic counselor training and education, and genetic counseling research.
Design, synthesis, and bioactivity evaluation of novel thiochromanone derivatives containing an oxime or oxime ether moiety
Authors: Yu Lu , Xiao Lingling , Chi Jiyan , Tang Zhangfei , Li Jie , Tan Shuming , Li Pei 
Published: July 2021

AbstractIn this study, using botanical active component thiochromanone as the lead compound, a series of novel thiochromanone derivatives containing an oxime or oxime ether moiety were designed and synthesized. The half‐maximal effective concentration (EC50) values of compound 4a against Xanthomonas oryzae pv. oryzae (Xoo), Xanthomonas oryzae pv. oryzicolaby (Xoc), and Xanthomonas axonopodis pv. citri (Xac) were 6, 10, and 15 μg/ml, respectively, which were superior to those of Bismerthiazol and Thiodiazole‐copper. Meanwhile, compound 4a also revealed better antifungal activity against Botrytis cinerea, with the EC50 value of 18 μg/ml, than that of Carbendazim. To the best of our knowledge, this is the first report on the antibacterial and antifungal activities of this series of novel thiochromanone derivatives containing an oxime or oxime ether moiety.
Z‐Score Reference Ranges for Umbilical Vein Diameter and Blood Flow Volume in Normal Fetuses
Authors: Wang Ling , Zhou Qichang , Zhou Chunhui , Wang Jiqing , Shi Chunlan , Long Baiguo , Hu Li , Peng Yang , Liu Yuchan , Xu Ganqiong 
Published: July 2021

ObjectivesTo establish Z‐scores for the diameter and blood flow volume of the umbilical vein (UV) in normal fetuses.MethodsThis was a prospective study involving 907 normal fetuses. We measured the diameter (Duv) of two different segments of the UV (FUV: the free loop of the UV; FIUV: the fetal intra‐abdominal UV). Next, we calculated the blood flow volume (Quv). Z‐scores were created for both Duv and Quv using gestational age, femur length, and biparietal diameter as independent variables.ResultsWe successfully acquired 858 (94.6%) normal fetal measurements. Between 20 and 39 weeks, the Duv of the FUV and FIUV increased from 0.38 to 0.80 cm and from 0.33 to 0.70 cm, respectively. The Quv of the FUV and FIUV increased from 32.66 to 381.88 ml/min and from 31.50 to 360.15 ml/min, respectively. Linear or quadratic regression models were best fitted between the parameters of UV and the independent variables. Z‐scores were successfully determined for both the Duv and Quv.ConclusionsThe calculation of Z‐scores for the Duv and Quv is simple by applying standard statistical methods. These Z‐scores may be useful to evaluate placental circulation and provide a rationale for monitoring and evaluating the prognosis of fetuses.
Dual‐band bandpass to bandstop switchable filter with independently tunable center frequency and bandwidth
Authors: Narayana Shriman , Singh Yatendra Kumar 
Published: July 2021

AbstractThis article presents a dual‐band bandpass (BP) to bandstop (BS) switchable filter with independently tunable center frequency and bandwidth. Two different length half‐wavelength resonators are coupled with two separate coupling lines. Each resonator consists of a varactor‐loaded stub at the center to tune the even mode frequencies, whereas two identical varactors are connected at the ends to tune odd and even mode frequencies simultaneously. The center frequency of the first passband is tuned from 1.03 to 1.4 GHz with constant fractional bandwidth (CFBW) of 3.4%, and second passband from 1.35 to 1.74 GHz with CFBW of 2%. BP to BS switching is achieved by connecting a p‐i‐n diode between input and output feedlines.
Initial performance predicts improvements in computerized cognitive training: Evidence from a selective attention task
Authors: Zhang Pan , Wu Di , Shang Yunfeng , Ren Weicong , Liang Jin , Wang Liyun , Li Chenxi 
Published: July 2021

AbstractComputerized cognitive training (CCT) has been found to improve a range of skills such as attention, working memory, inhibition control, and decision making. However, the relationship between the initial performance, amount of improvement, time constant, and asymptotic performance level in CCT is still unclear. In the current study, we performed selective attention training on college students and addressed this issue by mathematically modeling the learning curve with an exponential function. Twenty‐nine students completed approximately 10 days of CCT. Presentation time served as the dependent variable and was measured by three‐down/one‐up adaptive algorithms. We fitted an exponential function to the estimated block thresholds during CCT and obtained three learning parameters (amount of improvement, time constant, and asymptotic performance level) for all subjects. The initial performance was defined by the sum of the amount of improvement and the asymptotic performance level. Pearson correlation analyses were conducted between the initial performance and the three leaning parameters. The initial performance was positively correlated with the amount of improvement and asymptotic performance level, but was negatively correlated with the time constant. The time constant was negatively correlated with the amount of improvement and asymptotic performance level. Poorer initial performance was linked to a larger amount of improvement, shorter time constant, and higher asymptotic threshold, which supported the compensation account. Our results may help improve the present understanding of the nature of the CCT process and demonstrate the advantages of using a customized training protocol to enhance the efficiency of cognitive training in practical applications.