bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis and design of wireless power transfer system based on inductor‐capacitor‐capacitor/none magnetic integration compensation circuit
Authors: Liu Zhimeng , Wang Lifang , Tao Chengxuan , Li Shufan , Guo Yanjie , Li Fang 
Published: July 2021

AbstractThis paper presents the analysis and design of the wireless power transfer (WPT) system based on the inductor‐capacitor‐capacitor/none (LCC/N) magnetic integration compensation circuit. Compared with the traditional compensation circuits, the proposed LCC/N compensation circuit features the magnetic integration and the secondary side without compensation network, which makes the WPT system more compact. First, the fundamental‐harmonic model considering the coupling relationship among magnetically integrated compensation inductor, transmitter coil, and receiver coil is established. Then, the reactive power and turn‐off current of the inverter, transmission power, and efficiency of the WPT system employing LCC/N compensation circuit are analyzed with varied coupling coefficient and load. Furthermore, based on the characteristics analysis of the LCC/N topology, the parameter design criterion of the LCC/N compensation circuit is given. Finally, the analysis and design of the WPT system based on the LCC/N magnetic integration compensation circuit are verified by simulations and experiments. The results show that the characteristics analysis of the WPT system employing the LCC/N compensation circuit is accurate, the inverter can realize zero‐voltage‐switch (ZVS) and the WPT system can achieve the rated power of 1 kW under different offset distances of coils and reach the maximum efficiency of 95.3%.
Ambivalence, Virtual Piety, and Rebranding: Social Media Uses among Tablighi Jama'at in Indonesia
Authors: Kuncoro Wahyu 
Published: July 2021

AbstractAdvanced smartphone technology and easy access to the internet have contributed to the embeddedness of social media in the daily lives of many Indonesians. However, among conservative Muslims, social media are regarded as potentially harmful, and their use is largely discouraged. The article discusses the ambivalence that characterizes social media usage within the Tablighi Jama'at, an Islamic reformist movement known for its missionary activities. Many Tablighis believe that social media potentially imperils their faith as it provides access to a wide range of non‐Islamic content, a perspective that has led to restrictions on smartphone use and internet access. Yet, as this article highlights, several social media platforms, such as Instagram and Facebook, are widely used among Indonesian Tablighis as they consider these platforms as a means to improve the efficacy of their face‐to‐face preaching and to display their pious practices as well as their personal transformations to a more pious self. In addition, their virtual piety goes hand in hand with attempts to rebrand their movement by countering negative stereotypes and by trying to position themselves as legitimate Islamic player in Indonesia.
Online Halal Dating, Ta'aruf, and the Shariatisation of Matchmaking among Malaysian and Indonesian Muslims
Authors: Nisa Eva F. 
Published: July 2021

AbstractHalal (permissible according to Islamic law) matchmaking and anti‐dating campaigns and businesses have mushroomed since the 2000s in Indonesia and neighbouring Malaysia. In Malaysia, the Soul Seekers of Marriage Conference was established in 2008 and Halal Speed Dating was launched in 2014. In Indonesia, Rumah Taaruf MyQuran (MyQuran's House to Get to Know Each Other) was founded in 2014 and Indonesia Tanpa Pacaran (Indonesia Without Dating) in 2015. In both countries, the presence of the internet and social media platforms coincided with Islam playing a greater role in public life. The thriving presence of Sharia‐compliant matchmaking businesses using advanced communication technology signifies both the strengthening of conservativism and the manifestation of the growth of contemporary Muslim publics. This article will focus on the role of the internet and social media in Sharia‐compliant matchmaking. Islamic theological doctrine stipulates that the Prophet Muhammad emphasised marriage as half of religion, denoting the importance of marriage to guard the chastity of Muslims. Therefore, the halal matchmaking and ta'aruf (getting to know each other) business have a flourishing market. The border between halal and non‐halal online transactional matchmaking is, however, contestable. Online halal matchmaking also invites greater nuances in understanding the freedom and agency of Muslim women.
Digital Theology: Saintly Marvels and God‐talk on Facebook
Authors: Alatas Ismail Fajrie 
Published: July 2021

AbstractAmong Indonesia's traditionalist Muslims, anecdotes of saintly marvels (karāma) relating occurrences that contradict reason or human understanding of nature are lodged in everyday conversations. While scholars have noted how recounting and listening to karāma anecdotes is believed by Muslims to transmit the blessing (baraka) of the saints and facilitate their intercession, this article explores such anecdotes' capacity to engender conversations about God and other issues pertaining to religious belief. It does so by observing the circulation of karāma anecdotes among Indonesia's traditionalist Muslims on Facebook and their role in provoking a variety of God‐talk. The circulation of such anecdotes affords their publics with the ability to assent to, engage with, debate, and question theological propositions. Facebook creates the material preconditions for the production and circulation of accessible and shareable karāma anecdotes that enables Muslims beyond the scholastic elites to participate in theological discussion and reflection while facilitating digital practices that can be construed as theologically meaningful. It also facilitates various disputations, including those that are theological, between Muslims adhering to different Islamic currents. Far from simply being a channel of communication or a mode of dissemination, Facebook may indeed come to function as a digital infrastructure of theology.
Investigation of the Supramolecular Assembly of Luminescent Lanthanide Nanoparticles Surface Functionalized by p‐Sulfonato‐Calix[4]arenes with Charged Aromatic Compounds
Authors: Cheignon Clémence , Heurté Margaux , Knighton Richard C. , Kassir Ali A. , Lecointre Alexandre , Nonat Aline , Boos Anne , Christine Câline , Asfari Zouhair , Charbonnière Loïc J. 
Published: July 2021

AbstractThe surface coordination of p‐sulfonato‐ (C[4]), p‐sulfonatothia‐ (SC[4]) and p‐sulfonato‐sulfoxocalix[4]arene (SO2C[4]) on La0.9Tb0.1F3 nanoparticles (TbNP) was investigated by UV‐Vis absorption and luminescence spectroscopies. SO2C[4] displayed the strongest affinity towards the NPs and a significant antenna effect leading to observation of the characteristic Tb emission bands upon calixarene excitation. NPs decorated by a shell of SO2C[4] were prepared and the interaction with rhodamine 6G (R6G) was studied. The progressive addition of R6G resulted in a strong Tb to R6G energy transfer process, as revealed by a long lived emission of R6G upon SO2C[4] excitation. The FRET efficiency was almost quantitative (87–90 %), pointing to an average distance of 28 to 32 Å between the R6G and the Tb emitting centres of the NP. An association of one R6G per SO2C[4] was deduced with a very strong apparent affinity (K=2.5×107 M−1) in water. Similar interactions were observed with paraquat, resulting in TbNP luminescence quenching. In both cases, an unexpected increase of the association constant of the cation with SO2C[4] was observed when SO2C[4] is anchored at the surface of the NP.
Global and gene‐specific promoter methylation, and micronuclei induction in lead‐exposed workers: A cross‐sectional study
Authors: Wang Kan , Meng Yu , Wang Tuanwei , Tu Yuting , Gong Shiyang , Zhang Guanghui , Au William , Xia Zhaolin 
Published: July 2021

AbstractPerturbation of epigenetic regulation is a well‐established mechanism for cancer but its role for lead (Pb)‐associated toxicity has not been adequately investigated. We aimed to investigate whether occupational Pb exposure is associated with micronuclei (MN) frequency and to further explored the mediating roles of epigenetic gene regulation. All the Pb‐exposed workers recruited from a Chinese acid battery factory, blood lead levels (BLLs) and MN frequency in lymphocytes were measured. In addition, methylation levels of seven genes (Line‐1, RASSF1A, RUNX3, p16, CYP26C1, hMLH1, p15) were examined among 230 workers. Robust Poisson regression model was used to investigate the association between BLLs and MN frequency. Mediation analysis was used to explore the mediating role of specific DNA methylation. Among total 677 participants, 71% were male, median BLLs was 229.1 μg/L (P25 = 155.5, P75 = 319.3; ranged from 8.9 to 647.7 μg/L), mean MN frequency was 2.5‰ (SD = 1.8‰; ranged from 0 to 9‰). Results from base model, adjusted for age, sex, and body mass index, showed that MN frequency would increase 1.38 (95%confidential interval: 1.34, 1.43) per 100 μg/L increment in BLLs. Using categorized exposure variable analyses, a BLLs dose–response increase in MN frequency was observed: 2.74 (2.13, 3.51), 3.43 (2.73, 4.32), 4.41 (3.89, 5.01) to 6.86 (6.02, 7.81). Mediation analysis indicated that Line‐1 methylation significantly mediated 3.6% of the association of BLLs with MN frequency. Occupational Pb exposure induces MN frequency in a dose–response relationship. Part of this association was mediated by Line‐1 promotor methylation.
Alterations in resting‐state functional connectivity in pediatric patients with tuberous sclerosis complex
Authors: Lobanov Oleg V. , Shimony Joshua S. , Kenley Jeanette , Kaplan Sydney , Alexopoulos Dimitrios , Roland Jarod L. , Smyth Matthew D. , Smyser Christopher D. 
Published: July 2021

AbstractObjectiveTo investigate resting‐state functional connectivity (FC) in pediatric patients with tuberous sclerosis complex and intractable epilepsy requiring surgery.MethodsResting‐state functional MRI was utilized to investigate functional connectivity in 13 pediatric patients with tuberous sclerosis complex (TSC) and intractable epilepsy requiring surgery.ResultsThe majority of patients demonstrated a resting‐state network architecture similar to those reported in healthy individuals. However, preoperative differences were evident between patients with high versus low tuber burden, as well as those with good versus poor neurodevelopmental outcomes, most notably in the cingulo‐opercular and visual resting‐state networks. One patient with high tuber burden and poor preoperative development and seizure control had nearly normal development and seizure resolution after surgery. This was accompanied by significant improvement in resting‐state network architecture just one day postoperatively.SignificanceAlthough many patients with tuberous sclerosis complex and medically refractory epilepsy demonstrate functional connectivity patterns similar to healthy children, relationships within and between RSNs demonstrate clear differences in patients with higher tuber burden and worse outcomes. Improvements in resting‐state network organization postoperatively may be related to epilepsy surgery outcomes, providing candidate biomarkers for clinical management in this high‐risk population.
Human papillomavirus infection and tumor microenvironment are associated with the microbiota in patients with oropharyngeal cancers—pilot study
Authors: Zakrzewski Martha , Gannon Orla Margaret , Panizza Benedict James , Saunders Nicholas Andrew , Antonsson Annika 
Published: July 2021

AbstractBackgroundPrevious microbiome studies of oropharyngeal cancer have shown that there are differences in the oral microbiota between human papillomavirus (HPV)‐positive and HPV‐negative patients.MethodsWe collected saliva, normal tissue, and tumor biopsies from 13 patients with oropharyngeal cancer (eight HPV‐positive, five HPV‐negative). We obtained basic clinical data from each patient. Extracted DNA was 16S rRNA gene sequenced. Analysis was based on HPV status and sample site using univariate, multivariate, and mixed effect regression methods.ResultsMultivariate analysis methods separated samples based on HPV status (Adonis, p < 0.001). Comparison of patients showed that there were significant changes in microbial richness across all sites based on HPV status (linear mixed effects regression, p = 0.0002).ConclusionsWe found significant differences in overall microbial community and bacterial richness between oropharyngeal patients based on HPV status. Our results suggest that there are significant differences in the microbiome in patients with oropharyngeal cancer based on HPV status.
Determinants of cognition in autoimmune limbic encephalitis—A retrospective cohort study
Authors: Mueller Christoph , Langenbruch Lisa M. , Rau Johanna M. H. , Brix Tobias , Strippel Christine , Dik Andre , Golombeck Kristin S. , Moenig Constanze , Raeuber Saskia J. , Kovac Stjepana , Wiendl Heinz , Meuth Sven G. , Bölte Jens , Johnen Andreas , Melzer Nico 
Published: July 2021

AbstractAutoimmune limbic encephalitis (ALE) is the most common type of autoimmune encephalitis (AIE). Subacute memory disturbance, temporal lobe seizures, and psychiatric symptoms are clinical hallmarks of the disease. However, little is known on the factors contributing to cognitive functioning in ALE. Hence, we here investigate major determinants of cognitive functioning in ALE. In a retrospective analysis of 102 patients with ALE, we first compared verbal learning capacity, nonverbal learning capacity, and attentional and executive functioning by absence or presence of different types of neural autoantibodies (AABs). Subsequently we established three linear regression models including 63, 38, and 61 patients, respectively to investigate how cognitive functioning in these domains may depend on common markers of ALE such as intrathecal inflammation, blood‐cerebrospinal fluid (CSF)‐barrier function, mesiotemporal epileptiform discharges and slowing, determined by electroencephalography (EEG) and structural mesiotemporal changes, measured with magnetic resonance imaging (MRI). We also accounted for possible effects of cancer‐ and immunotherapy and other centrally effective medication. There was no effect of AAB status on cognitive functioning. Although the regression models could not predict verbal and nonverbal learning capacity, structural mesiotemporal neural network alterations on T2‐/fluid attenuated inversion recovery (FLAIR)‐signal‐weighted MRI and mesiotemporal epileptiform discharges or slowing on EEG exerted a significant impact on memory functions. In contrast, the regression model significantly predicted attentional and executive functioning with CSF white blood cell count and centrally effective medication being significant determinants. In this cohort, cognitive functioning in ALE does not depend on the AAB status. Common markers of ALE cannot predict memory functioning that only partially depends on structural and functional alterations of mesiotemporal neural networks. Common markers of ALE significantly predict attentional and executive functioning that is significantly related to centrally effective medication and CSF white blood cell count, which may point toward inflammation affecting brain regions beyond the limbic system.
Skeletal adverse events in childhood cancer survivors: An Adult Life after Childhood Cancer in Scandinavia cohort study
Authors: Oskarsson Trausti , Duun‐Henriksen Anne Katrine , Bautz Andrea , Montgomery Scott , Harila‐Saari Arja , Petersen Cecilia , Niinimäki Riitta , Madanat‐Harjuoja Laura , Tryggvadóttir Laufey , Holmqvist Anna Sällfors , Hasle Henrik , Heyman Mats , Winther Jeanette Falck ,   ALiCCS study group
Published: July 2021

AbstractThe dynamic growth of the skeleton during childhood and adolescence renders it vulnerable to adverse effects of cancer treatment. The lifetime risk and patterns of skeletal morbidity have not been described in a population‐based cohort of childhood cancer survivors. A cohort of 26 334 1‐year cancer survivors diagnosed before 20 years of age was identified from the national cancer registries of Denmark, Finland, Iceland and Sweden as well as a cohort of 127 531 age‐ and sex‐matched comparison subjects randomly selected from the national population registries in each country. The two cohorts were linked with data from the national hospital registries and the observed numbers of first‐time hospital admissions for adverse skeletal outcomes among childhood cancer survivors were compared to the expected numbers derived from the comparison cohort. In total, 1987 childhood cancer survivors had at least one hospital admission with a skeletal adverse event as discharge diagnosis, yielding a rate ratio (RR) of 1.35 (95% confidence interval, 1.29‐1.42). Among the survivors, we observed an increased risk for osteonecrosis with a RR of 25.9 (15.0‐44.5), osteoporosis, RR 4.53 (3.28‐6.27), fractures, RR 1.27 (1.20‐1.34), osteochondropathies, RR 1.57 (1.28‐1.92) and osteoarthrosis, RR 1.48 (1.28‐1.72). The hospitalization risk for any skeletal adverse event was higher among survivors up to the age of 60 years, but the lifetime pattern was different for each type of skeletal adverse event. Understanding the different lifetime patterns and identification of high‐risk groups is crucial for developing strategies to optimize skeletal health in childhood cancer survivors.
What time use surveys can (and cannot) tell us about labor supply
Authors: Chou Cheng , Shi Ruoyao 
Published: July 2021

SummaryThe American Time Use Survey (ATUS) accurately measures hours worked on a single day. We propose several estimators of elasticities of weekly labor supply in a linear regression model, despite certain impossibility results due to the time specific feature of the ATUS. We recommend the impute estimator, a simple modification of the standard two stage least squares estimator, that imputes the dependent variable using daily subsamples, based on our careful investigation of asymptotic and finite sample properties of the estimators under the potential outcome framework. We apply the impute estimator to the ATUS and find substantially different elasticity estimates from the Current Population Survey, especially for married women.
Efficient workflow for the investigation of the catalytic cycle of water oxidation catalysts: Combining GFN‐xTB and density functional theory
Authors: Menzel Jan Paul , Kloppenburg Martijn , Belić Jelena , de Groot Huub J. M. , Visscher Lucas , Buda Francesco 
Published: July 2021

AbstractPhotocatalytic water oxidation remains the bottleneck in many artificial photosynthesis devices. The efficiency of this challenging process is inherently linked to the thermodynamic and electronic properties of the chromophore and the water oxidation catalyst (WOC). Computational investigations can facilitate the search for favorable chromophore‐catalyst combinations. However, this remains a demanding task due to the requirements on the computational method that should be able to correctly describe different spin and oxidation states of the transition metal, the influence of solvation and the different rates of the charge transfer and water oxidation processes. To determine a suitable method with favorable cost/accuracy ratios, the full catalytic cycle of a molecular ruthenium based WOC is investigated using different computational methods, including density functional theory (DFT) with different functionals (GGA, Hybrid, Double Hybrid) as well as the semi‐empirical tight binding approach GFN‐xTB. A workflow with low computational cost is proposed that combines GFN‐xTB and DFT and provides reliable results. GFN‐xTB geometries and frequencies combined with single‐point DFT energies give free energy changes along the catalytic cycle that closely follow the full DFT results and show satisfactory agreement with experiment, while significantly decreasing the computational cost. This workflow allows for cost efficient determination of energetic, thermodynamic and dynamic properties of WOCs.
Population Pharmacokinetic Modeling and Simulations to Evaluate a Potential Dose Regimen of Testosterone Undecanoate in Hypogonadal Males
Authors: Pastuszak Alexander W. , Bush Mark , Curd Laura , Vijayan Saji , Priestley Tony , Xiang Qinfang , Hu Yiqun 
Published: July 2021

AbstractIntramuscular testosterone undecanoate is indicated as testosterone replacement in adult males with a deficiency in or absence of endogenous testosterone (hypogonadism). Intramuscular testosterone undecanoate 750 mg is approved to be administered at initiation and at 4 weeks, followed by a maintenance dose every 10 weeks. However, a more frequent maintenance regimen may improve symptom management of low testosterone at the end of each dosing interval. The current objective was to develop a population pharmacokinetic (PK) model for intramuscular testosterone undecanoate 750 mg and to perform PK simulations to assess the impact of an 8‐week maintenance regimen on testosterone exposure. A 1‐compartment model with first‐order absorption and first‐order elimination best described the PK of testosterone undecanoate. The model included time‐dependent suppression and gradual recovery of endogenous testosterone production during testosterone undecanoate administration. Significant covariates included body weight and sex hormone–binding globulin level. With the final PK model, simulations were performed to evaluate the impact of an 8‐week vs a 10‐week maintenance regimen on testosterone exposure. The 8‐week testosterone undecanoate regimen had a predicted 11% increase in average concentration and last observed concentration during a dosing interval before a subsequent dose and a 5% increase in maximum concentration. This translated into an ≈10% increase in the percentage of patients predicted to have a last observed concentration during a dosing interval before a subsequent dose >300 ng/dL, minimal change in the percentage of patients with average concentration in the normal range, and a low likelihood of maximum concentration >2500 ng/dL. These simulations suggest that more frequent administration of intramuscular testosterone undecanoate may be beneficial in some patients. Further clinical evaluation of an 8‐week dose regimen is warranted.
The effect of immediate dentin sealing with chlorhexidine pretreatment on the shear bond strength of dual‐cure adhesive cement
Authors: Deniz Sule Tugba , Oglakci Burcu , Yesilirmak Sevda Ozturk , Dalkilic Evrim Eliguzeloglu 
Published: July 2021

AbstractThe purpose of this in vitro study was to evaluate the effect of immediate dentin sealing (IDS) with and without chlorhexidine (CHX) pretreatment on the shear bond strength (SBS) of dual‐cure adhesive resin cement. Mid‐coronal dentin surfaces were obtained from 75 human molars. They were randomly allocated into five groups in accordance to type of IDS [etch&rinse/ER (Adper Single Bond2) and universal/U adhesive systems (Single Bond Universal)] and presence of CHX application (n = 15): Group ER; Group ER + CHX; Group U; Group U + CHX; and Group C (no IDS). Dual‐cure adhesive resin cements were bonded with a cylinder‐shaped Teflon mold. The SBS was measured using a universal test machine. Fracture type was evaluated with stereomicroscope. The resin/dentin interfaces were examined with an environmental scanning electron microscope. Data were statistically analyzed with two‐way analysis of variance and Bonferroni tests (p < .05). Regarding the IDS treatment groups with/without CHX, there were no significant differences in SBS (p > .05). Group U + CHX showed significantly higher SBS than Group C (p < .05). Regarding the presence of CHX, no significant differences in SBS were found (p > .05). The prevalent failure mode was the mixed type for most of the groups. Group C exhibited an intact and regular hybrid layer with no resin tag, whereas longer and clear resin‐tag formation was visible for Group U + CHX. CHX pretreatment improved the bond strength between adhesive resin cement and dentin when IDS treatment was performed with a universal adhesive system.