bluuebunny/crossref_metadata_2025_split huggingface dataset:
A systematic review and meta-analysis of the efficacy and safety of remdesivir in COVID-19 patients
Authors: Saha Sumanta , Saha Sujata 
Published: March 2021

Background: This systematic review compares the efficacy and safety of remdesivir between its recipient and non-recipient COVID-19 patients from the recently published randomized controlled trials (RCT).
Methods: For eligible trials comparing the above outcomes, a literature search took place in the PubMed database. The reviewed trials data were abstracted and critically appraised using the Cochrane tool. Then, a random-effect meta-analysis followed to compare the risk between the compared interventions in risk ratio (RR). By plying the I2 and Chi2 statistics, the heterogeneity estimation happened. A sensitivity analysis iterated the preliminary meta-analysis using a fixed-effect model.
Results: Two eligible RCTs included in this review sourced data from about 833 COVID-19 patients from 115 hospitals in Asia, Europe, and the US. The risk of bias was primarily low. Random-effect meta-analysis suggested a clinical improvement (RR: 1.09; 95% CI: 1.02, 1.16; P=0.02; I2: 0%) and decrease in the risk of any serious side effects (RR: 0.64; 95% CI: 0.43, 0.94; P<0.001; I2: 0%) in the remdesivir treated COVID-19 patients. The rest of the outcomes did not vary between the juxtaposed interventions.
Conclusion: Evidence-based on early RCTs suggest that remdesivir is a clinically useful and safe drug to treat COVID-19 patients.
Duration of functional stability to non-specific aerobic load in wrestlers
Authors: Chikov A. E. , Pavlova A. N. , Naumov A. V. , Medvedev D. S. 
Published: March 2021

Objective: study the duration of establishment of functional stability to non-specific stress in wrestlers.Materials and Methods. Nineteen athletes in martial arts, mid-age 23 ± 3 years of age, participated in the study. The qualification level of the subjects ranged from first sport grade to Master of Sport. A series of sports training was organized within 4 weeks. Each train consisted of a smooth-running load of 40 minutes at a speed corresponding to the anaerobic exchange threshold (AET). The indicators of the duration of reaching the AET level by heart rate (HR), the power of the low frequency and high frequency component of the spectrum were analyzed.Results. The effect of urgent adaptation, in the form of an extension of the duration the heart rate on the anaerobic threshold level from 29 to 32 mines and the increase in the regulation of vegetative nervous system by increasing the total power of the spectrum observed on the third day of the training cycle. From the third to ninth days of the study, fatigue occurs, as can be seen from the lowering of the anaerobic threshold time to 21 minutes, as well as the lowering of the high-frequency part of the vegetative nervous system regulatory spectrum. The emergency adaptation ends by 9 days of observation, after four high-intensity exercises, which manifests itself in stabilizing the regulation of the heart rate, vegetative nervous system goes from a reflex level to a lower one — a humeral metabolic level. The time to reach the HR in the aerobic threshold will stabilize at 21–23 minutes.Conclusions. Functional stability to the non-specific aerobic load in the wrestlers emerged by the twentyseventh day of the study after ten highly intensive aerobic exercises, which confirmed by the results of the time dynamics of the tine of HR in aerobic threshold and analysis of spectrum results of HRV.
Validación del método de elaboración tradicional del extracto de vainilla (Vanilla planifolia A.) en la Sierra de Otontepec
Authors: Solares del A. C. D. , Elorza Martínez Pablo , Rodríguez B. A. , López C. R. D. , Aguirre López E. 
Published: March 2021

El objetivo del trabajo fue evaluar el método de elaboración tradicional de los extractos elaborados con refino artesanal, procedentes de la región de la Sierra de Otontepec Veracruz, con el propósito de conocer sus características y generar información para determinar las ventajas de la concentración de vainillina que presenta cada una de las muestras analizadas. Se obtuvieron los perfiles químicos y se identificaron compuestos químicos utilizando columnas cromatografías además del perfil químico general, encontrando que el contenido de alcohol en los extractos, que elaboran los productores cuenta únicamente con el 14% de alcohol y lo mencionado en la NMX-FF-074-1996 dice que no debe ser menor del 30% por lo que no cumple con este requisito. Con respecto al contenido de vainillina los contenidos variaron de 348 a un 8,447 % (pm) por lo que cumplen con la Norma Oficial Mexicana que señala que el contenido mínimo de los extractos debe ser de 2,49 % en adelante, por lo tanto los extractos regionales se encuentran dentro de los parámetros y son aptos para su venta.
Improving The Students’ Writing Ability In Descriptive Text Through Think-Talk-Write Strategy
Authors: Setiawati Isye , Zuniati Mai 
Published: March 2021

This research is a Classroom Action Research (CAR). The subject of this research is tenth grade of MA Ma‘arif Roudlotut Tholibin Metro academic year 2018/2019 especially at class X Sains. It is consists of twenty three students. The data collecting techniques are test, observation, and questionnaire. The analysis of the data by using qualitative and quantitative data. The result showed that the students’ score in preliminary study, there was no one who passed the passing grade. Then, in the first cycle it is found that there were 12(52%) students who passed and the rest is 11(47%) students could not pass the passing grade. In cycle 2 there were an increase from cycle 1, that was 20(86%) students reached the passing grade and only 3(13%) who failed to accomplish the passing grade. The researcher concluded that TTW Strategy can improve students‘ writing ability in descriptive text. This showed of students‘ activities by observation, students‘ response by questionnaire, and students‘ score by test. The researcher found some dates that students interested, any progress when learned writing descriptive text by using Think-Talk-Write as strategy and the students felt better and improved for their writing ability in descriptive text. From observation students‘ active in the class. In cycle 2, 20(86%) students reached the passing grade and only 3(13%) who failed to accomplish the passing grade It indicated that think-talk-write strategy has considerable influence toward students’ writing ability in descriptive text and success
Key words: Think-Talk-Write Strategy, Writing, Descriptive text
Peningkatan Motivasi Hasil Belajar Ekonomi Melalui Model Pembelajaran Student Centered Learning
Authors: Mastufah Mastufah 
Published: March 2021

In the process of learning Economics (Accounting) required a certain strategy and strong motivation. Teachers play a very important role, especially in terms of designing learning scenarios. Teachers should be able to choose a learning model that can increase the motivation of learners, in accordance with the characteristics of subjects, and characteristics of learners so that learning can take place optimally. The aim of this classroom action research is to improve the learning of learners using the student centered learning model. This research was conducted in class XI IPS1, MAN 1 Cilegon semester 1, material Posting from Juku Kebuku Besar Journals, post to a subsidiary "using cycles, in this study the author tries to 2 cycles. The results show that in each cycle of understanding the accounting, cycle of a merchandising company on post material from a special journal to the ledger, posting to the auxiliary book, gained increased motivation and learning outcomes. In general it can be concluded that the use of student centered learning model can improve the motivation and learning outcomes of learners.
Key words: Student Centered Learning Model, Learn Economics Accounting
Interferensi Bahasa Indonesia ke dalam Bahasa Arab di Pondok Roudlatul Qur’an Metro Lampung
Authors: Amalia Dian Risky , Hidayatullah Rizky , Anwar Muhammad Saidun , Irhamudin Irhamudin 
Published: March 2021

The aim of the study focuse on the interference of Indonesian into Arabic viewed from various aspects such as phonological aspects, morphology, syntax, lexicology, and the causes of such interference, namely about the first language interference of santri to their Arabic pronunciation in Rhoudhatul Qur'an Islamic Boarding School on in 2018. In essence, research is an attempt made to look deeply at the identity of the object of research. Because the object of language research cannot be present alone, without research. And the research that will be conducted is by describing the object of research. Using triangulation observation, interviews, and documentation. The findings obtained by the researcher are as follows: 1) Phonological interference occurs in the letters and letters of letters which results in deviations of meaning, Morphological interference occurs in reduplications that often occur in Indonesian, which results in reduplication in Arabic, in Arabic call it jama ', syntactic interference occurs when the word is decapitated freely in a sentence structure without knowing the elements of the language are standard or not in the rules of Indonesian, so that it adversely affects Arabic, lexicological interference occurs in compound words in Indonesian, whereas in Arabic not all words have compound words which consist of two words, semantic interference occurs in the use of language which deviates from its meaning due to differences between Indonesian and Arabic, Arabic has root words, whereas in Indonesian it does not all words have root words.2) The cause of interference is due to habits that have become cultural, tides ebb and control of language, lack of knowledge, and the difficulty of cultivating good language. Hopefully it can become a reference for further research.
Key words: Interference, Indonesian, Arabic
A European map of groundwater pH and calcium
Authors: Hájek Michal , Jiménez-Alfaro Borja , Hájek Ondřej , Brancaleoni Lisa , Cantonati Marco , Carbognani Michele , Dedić Anita , Dítě Daniel , Gerdol Renato , Hájková Petra , Horsáková Veronika , Jansen Florian , Kamberović Jasmina , Kapfer Jutta , Kolari Tiina Hilkka Maria , Lamentowicz Mariusz , Lazarević Predrag , Mašić Ermin , Moeslund Jesper Erenskjold , Pérez-Haase Aaron , Peterka Tomáš , Petraglia Alessandro , Pladevall-Izard Eulàlia , Plesková Zuzana , Segadelli Stefano , Semeniuk Yuliya , Singh Patrícia , Šímová Anna , Šmerdová Eva , Tahvanainen Teemu , Tomaselli Marcello , Vystavna Yuliya , Biţă-Nicolae Claudia , Horsák Michal 
Published: March 2021

Abstract. Water resources and associated ecosystems are becoming highly endangered due to ongoing global environmental changes. Spatial ecological modelling
is a promising toolbox for understanding the past, present and future distribution and diversity patterns in groundwater-dependent ecosystems, such
as fens, springs, streams, reed beds or wet grasslands. Still, the lack of detailed water chemistry maps prevents the use of reasonable models to be
applied on continental and global scales. Being major determinants of biological composition and diversity of groundwater-dependent ecosystems,
groundwater pH and calcium are of utmost importance. Here we developed an up-to-date European map of groundwater pH and Ca, based on 7577
measurements of near-surface groundwater pH and calcium distributed across Europe. In comparison to the existing European groundwater maps, we included several times more sites, especially in the regions rich in spring and fen habitats, and filled the apparent gaps in eastern
and southeastern Europe. We used random forest models and regression kriging to create continuous maps of water pH and calcium at the continental
scale, which is freely available also as a raster map (Hájek et al., 2020b; https://doi.org/10.5281/zenodo.4139912). Lithology had a higher importance than
climate for both pH and calcium. The previously recognised latitudinal and altitudinal gradients were rediscovered with much refined regional
patterns, as associated with bedrock variation. For ecological models of distribution and diversity of many terrestrial ecosystems, our new map
based on field groundwater measurements is more suitable than maps of soil pH, which mirror not only bedrock chemistry but also
vegetation-dependent soil processes.
IDENTIFIKASI TELUR CACING SOIL TRANSMITTED HELMINTH (STH) PADA MURID SEKOLAH DASAR NEGERI (SDN) 91 KECAMATAN RUMBAI PESISIR PEKANBARU
Authors: Aritonang Berliana N.R.S. , Rezki Nurul 
Published: March 2021

ABSTRAK
Infeksi kecacingan yang disebabkan oleh Soil Transmitted Helminth (STH) menjadi masalah kesehatan bagi masyarakat Indonesia khususnya anak-anak yang masih duduk di Sekolah Dasar (SD). Cacing usus yang ditularkan melalui tanah ini meliputi Ascaris lumbricoides, Trichuris trichiura, dan Cacing tambang (Necator americanus dan Ancylostoma duodenale). Tujuan penelitian ini adalah untuk mengetahui ada tidaknya telur cacing golongan Soil Transmitted Helminth (STH) pada murid Sekolah Dasar Negeri (SDN) 91 Kecamatan Rumbai Pesisir Pekanbaru. Metode yang digunakan adalah metode flotasi dan sedimentasi. Populasi pada penelitian ini adalah murid Sekolah Dasar Negeri (SDN) 91 Kecamatan Rumbai Pesisir Pekanbaru kelas 1, 2, dan 3. Hasil penelitian berdasarkan pemeriksaan mikroskopis dari 27 sampel ditemukan 2 sampel positif yaitu telur cacing Ascaris lumbricoides fertil pada sampel dengan kode M dan telur cacing Ascaris lumbricoides infertil dengan kode ZZ.

Kata kunci: Ascaris lumricoides, murid SD, pemeriksaan kualitatif feses, Soil Transmitted Helmint, Kecacingan
PENGARUH LAMA PENYIMPANAN TERHADAP KADAR HEMOGLOBIN PADA KANTONG DARAH DONOR DI BANK DARAH RUMAH SAKIT SANTA MARIA PEKANBARU
Authors: Saidjao Yuniyati 
Published: March 2021

ABSTRAK
Hemoglobin adalah pigmen pengangkut oksigen utama ke jaringan yang terdapat di eritrosit. Kadar hemoglobin digunakan sebagai syarat penentu terapi transfusi darah terhadap pasien anemia. Sebelum transfusi darah pada awalnya disimpan dalam kantong yang mengandung antikoagulan CPDA-1 dengan masa simpan 35 hari pada suhu 4 ± 2°C dengan sistem FIFO. Tujuan penelitian ini adalah mengetahui kadar hemoglobin kantong darah donor selama penyimpanan hari–1 dan setelah penyimpanan hari–15 di Bank Darah Rumah Sakt Santa Maria Pekanbaru sehingga transfusi efektif dilakukan untuk menaikan kadar hemoglobin pasien. Jenis penelitian menggunakan Quasi Eksperimen dengan desain penelitian one group pretest–postest. Sampel yang digunakan yaitu kantong darah WB dan PRC yang diperoleh dengan teknik purposive random sampling. Berdasarkan uji t–berpasangan pada kantong darah WB didapat p>0,01 artinya tidak ada perbedaan bermakna kadar hemoglobin hari–1 dan hari–15 sedangkan pada kantong darah PRC didapat p<0,01 artinya ada perbedaan bermakna kadar hemoglobin hari–1 dan hari–15.
Kata kunci : Hemoglobin, WB, PRC, lama penyimpanan.
Gambaran Kadar Ureum dan Kreatinin Serum pada Pasien Diabetes Melitus Tipe-2 di Rumah Sakit Santa Maria Pekanbaru
Authors: Trihartati Valentina 
Published: March 2021

Abstrak
Diabetes melitus merupakan penyakit gangguan metabolisme yang ditandai dengan meningkatnya kadar glukosa darah. Berdasarkan International Diabetes Federation (IDF), Indonesia merupakan urutan ke–7 negara yang memiliki kasus diabetes melitus terbesar. Penderita diabetes melitus ditandai dengan kadar glukosa darah pada waktu puasa ≥126 mg/dL dan 2 jam sesudah makan ≥200 mg/dL. Salah satu penyakit yang disebabkan karena komplikasi kronik mikrovaskuler pada penderita diabetes melitus adalah nefropati diabetik. Pemeriksaan ureum dan kreatinin merupakan cara paling sederhana untuk menilai status fungsional ginjal. Tujuan penelitian ini untuk mengetahui gambaran kadar ureum dan kreatinin pada penderita diabetes melitus tipe–2 di Rumah Sakit Santa Maria Pekanbaru periode Sempember–November 2018. Berdasarkan data pasien yang telah diperoleh, penderita diabetes melitus dengan kadar ureum >39 mg/dL (tinggi) paling banyak diderita oleh perempuan (9 orang), pada usia 55–64 tahun (4 orang), lama menderita 21–25 bulan (3 orang) dan dengan penyakit penyerta (7 orang). Kadar kreatinin >1,3 mg/dL (tinggi) paling banyak diderita oleh perempuan (7 orang), pada usia 55–64 tahun dan 65–74 tahun (6 orang), lama menderita 21–25 bulan (3 orang), dan dengan penyakit penyerta (6 orang). Berdasarkan penelitian ini dapat disimpulkan bahwa terjadi peningkatan kadar ureum dan kreatinin pada pasien diabetes melitus tipe–2 khususnya pada penderita perempuan.
Kata kunci : Diabetes melitus, nefropati diabetik, ureum, kreatinin
UJI LISIS TELUR Ascaris lumbricoides SETELAH PEMBERIAN GETAH PEPAYA (Carica papaya)
Authors: Adi Darmadi - 
Published: March 2021

Penyakit kecacingan tergolong penyakit neglected disease yaitu infeksi yang kurang diperhatikan dan penyakitnya bersifat kronis tanpa menimbulkan gejala klinis yang jelas dan dampak yang ditimbulkannya baru terlihat dalam waktu yang lama seperti kekurangan gizi, gangguan tumbuh kembang dan gangguan kecerdasan pada anak. Berbagai upaya yang telah dilakukan untuk mengeliminasi adanya cacing di dalam tubuh, mulai dari penggunaan obat sintetik hingga penggunaan obat alami. Salah satu obat alami yang dapat dijadikan sebagai antihelmintik adalah getah papaya (Carica papaya). Tujuan dari penelitian ini adalah untuk menentukan konsentrasi getah pepaya (Carica papaya) yang efektif terhadap lisisnya telur Ascaris lumbricoides. Metode yang digunakan dalam penelitian ini eksperimen laboratorium secara in vitro. Hasil yang di dapatkan dari penelitian adalah getah papaya pada konsentrasi 5% dapat menyebabkan lapisan albumin telur mengalami perubahan (menyerupai fertilized decorticated) pada waktu selama 60 menit, sedangkan getah papaya konsentrasi 1%-4% tidak mengalami perubahan yang signifikan. Kesimpulan dari penelitian ini adalah bahwa getah papaya pada konsentrasi 5% tidak menimbulkan lisis tetapi lapisan albumin dari telur mengalami perubahan menyerupai fertilized decorticated.

Kata kunci: lisis, Ascaris lumbricoides, Getah Pepaya.
Pengaruh Budaya Organisasi, Kepemimpinan, Motivasi Kerja Dan Kompetensi Terhadap Kinerja Pegawai LPP TVRI
Authors: Asraf  , Hamzah Nasir , Said Syahnur , Lamo Muchtar 
Published: March 2021

Penelitian ini bertujuan untuk mengetahui dan menganalisis (a). pengaruh budaya organisasi terhadap kinerja pegawai LPP TVRI, (b). kepemimpinan terhadap kinerja pegawai LPP TVRI, (c). motivasi kerja terhadap kinerja pegawai LPP TVRI dan (d) kompetensi terhadap kinerja pegawai LPP TVRI. Populasi penelitian ini sebanyak 176 orang yang terdistribusipada 3 stasiun LPP TVRI meliputi Sulawesi Tenggara, Sulawesi Selatan, dan Sulawesi Barat. Sampel menggunakan metode sensus dimanaseluruh responden dijadikan sebagai sampel. Alatanalisis menggunakan Partial Least Square (PLS) dengan program Smart PLS Versi 3.2. Adapun lokasi penelitian adalah TVRI Wilayah sulawesi selatan, Sulawesi Tenggara dan Sulawesi Barat Hasil penelitian bahwa; (a). budaya organisasi berpengaruh postif tidak signifikan terhadap kinerja pegawai LPP TVRI, kepemimpinan berpengaruh positif dan signifikan terhadap kinerja pegawai LPP TVRI, motivasi berepngaruh positif dan signifikan terhadap kinerja pegawai LPP TVRI dan kompetensi berpengaruh positif dan signifikan tehadap kinerja pegawai pegawai LPP TVRI.
This study aims to determine and analyze (a). the influence of organizational culture on the performance of LPP TVRI employees, (b). leadership on the performance of LPP TVRI employees, (c). work motivation on LPP TVRI employee performance and (d) competence on LPRI TVRI employee performance. The study population was 176 people distributed in 3 LPP TVRI stations covering Southeast Sulawesi, South Sulawesi and West Sulawesi. The sample uses the census method where all respondents are used as samples. Alatanalisis uses Partial Least Square (PLS) with Smart PLS Version 3.2. The research locations are TVRI in South Sulawesi, Southeast Sulawesi and West Sulawesi. (a). organizational culture does not have a significant positive effect on the performance of LPP TVRI employees, leadership has a positive and significant effect on the performance of LPP TVRI employees, motivation has positive and significant influence on the performance of LPP TVRI employees and competence has a positive and significant effect on employee performance of LPP TVRI employees.
Assessing the Legacy of “The Negro Speaks of Rivers” on its Centennial
Authors: Graham Shane 
Published: March 2021

Abstract
Langston Hughes published his first poem, “The Negro Speaks of Rivers,” in June 1921 in The Crisis magazine. The poem helped inaugurate the Harlem Renaissance, became Hughes's calling card, and established certain core themes of the vast body of work he would publish in the next half-century: the positive affirmation of Blackness; the deployment of a collective “I”; the catalog of place names evoking both global solidarity and historical particularity; and the use of water imagery to denote worldwide interconnection and link the world's oppressed populations to the human community. One hundred years after “Rivers” was first published, the Langston Hughes Review is devoting two issues to celebrating and assessing this important milestone in twentieth-century literature and the legacy that began with this single poem. This foreword contextualizes “The Negro Speaks of Rivers” and assesses its significance on its centennial. The poem feels topical and urgent in part because it was born into a time of crisis that resonates powerfully with our own moment.
Transforming Pittsburgh’s Economic Ecosystem and Clusters
Authors: Yablonsky Dennis 
Published: March 2021

The Pittsburgh region’s recovery and transformation from an economy dominated by heavy industry to a balanced and diversified economy throughout the region has been documented by many publications during the past decade. Pittsburgh is rightfully viewed as a model for post-industrial transformation and is positioned to provide sustainable careers and a high standard of living for its people. This article will not attempt to tell that broad economic recovery story again, but instead will focus on one important aspect of the story: the rise of Life Sciences/Biotech as one of the key clusters driving the Pittsburgh story. I had the privilege of being at the table for much of the planning and execution that went into the development of this cluster. In this article, I hope to provide a unique view of the key elements of the plan for Life Sciences in the Pittsburgh Region.