bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strategi penguatan kewarganegaraan ekologis pada Kelompok Tani Berdikari di Kota Banjarbaru
Authors: Fahlevi Reja , Kuncoro Alamanik Suryo 
Published: October 2021

The low awareness of citizens to care for and protect the environment has resulted in the environment being neglected and damaged. So that a strategy to strengthen ecological citizenship is needed in an effort to keep the environment cared for and cared for. This study aims to explore strategies implemented in farming with the concept of loving nature and sustainability. This study uses a qualitative approach with a case study method that investigates carefully and in detail about a program, event, or activity. The results showed that the strategy of strengthening ecological citizenship that had been carried out by the Berdikari farmer group was through the implementation of the concept of safe, secure, and healthy in processing their crops and protecting the surrounding environment, and collaborating with stakeholders, such as the agriculture agency. The obstacles encountered by farmers who are members of independent farmer groups in implementing this strategy are based on natural and economic factors.
Abstrak Rendahnya kesadaran warga negara untuk memelihara dan menjaga lingkungan, mengakibatkan lingkungan menjadi tidak terawat dan rusak. Sehingga diperlukan strategi penguatan kewarganegaraan ekologis sebagai upaya agar lingkungan tetap dirawat dan diperhatikan. Penelitian ini bertujuan ini untuk menggali strategi-strategi yang dilakukan dalam Bertani dengan konsep mencintai alam dan berkelanjutan. Penelitian ini menggunakan pendekatan kualitatif dengan metode studi kasus yang menyelidiki secara teliti dan detail mengenai sebuah program, peristiwa, maupun sebuah aktivitas. Hasil Penelitian menunjukan bahwa strategi penguatan kewarganegaraan ekologis yang sudah dilakukan oleh kelompok tani Berdikari melalui implementasi konsep aman, selamat, dan sehat dalam mengolah hasil taninya serta menjaga lingkungan sekitar, dan melakukan kerjasama dengan stakeholder, seperti dinas pertanian. Hambatan-hambatan yang ditemui para petani yang tergabung di dalam kelompok tani berdikari dalam meimplementasikan strategi ini dari faktor alam dan ekonomi.
Peran orang tua dalam pendidikan karakter peserta didik selama pembelajaran online
Authors: Haryanti Amelia , Dindin  
Published: October 2021

The purpose of this research is to find out the role of parents / guardians of learners in helping the character of learners during online learning in the covid-19 pandemic and the obstacles faced by parents during online learning. This research method uses a qualitative approach with case studies. The research subjects used were parents / guardians of learners in Pondok Benda Village, Pamulang District of South Tangerang City. Data collection techniques use observation, documentation, and interviews. The results of the research obtained are as follows: Parents are more trying to foster the character values of learners during online learning, parents provide real examples between subject matter and real examples in everyday life that can be witnessed and felt directly by learners in the environment where they live, while the obstacles faced by parents are the way of delivery in providing understanding of learning materials to learners, Not as good as teachers in school. To overcome these problems parents create a group with Civic Education teachers to jointly conduct supervision and consultation related to learning materials so that learners are maximal in understanding learning during online learning.
Mariposas Ithomiini (Nymphalidae) en un fragmento de bosque seco tropical del Valle del Cauca, Colombia
Authors: Saavedra Conde Nathalia , Osorio Domínguez Daniel , Kattan Gustavo H. 
Published: October 2021

Caracterizamos la estructura de la comunidad de mariposas Ithomiini en un remanente de bosque seco tropical del Valle del Cauca, Colombia, donde evaluamos los efectos de las variaciones climáticas sobre la abundancia. Estimamos la estructura de edades de los adultos evaluando el nivel de desgaste alar. Registramos once especies entre marzo y agosto de 2019. Las especies más abundantes fueron Mechanitis menapis, Mechanitis polymnia y Tithorea harmonia que representaron el 85 % de la abundancia relativa; no hubo variaciones significativas en los patrones de abundancia al comparar los resultados con estudios previos. La correlación entre las condiciones climáticas y la abundancia de mariposas fue significativa en ambos casos. Determinamos que el recambio de especies en la comunidad no es afectado por la temporada climática.
Numerical Comparison Between ES-MDA and Gradient-Based Optimization for History Matching of Reduced Reservoir Models
Authors: Reverón M. A. Borregales , Holm H. H. , Møyner O. , Krogstad S. , Lie K.-A. 
Published: October 2021

Abstract
The Ensemble Smoother with Multiple Data Assimilation (ES-MDA) method has been popular for petroleum reservoir history matching. However, the increasing inclusion of automatic differentiation in reservoir models opens the possibility to history-match models using gradient-based optimization. Here, we discuss, study, and compare ES-MDA and a gradient-based optimization for history-matching waterflooding models. We apply these two methods to history match reduced GPSNet-type models. To study the methods, we use an implementation of ES-MDA and a gradient-based optimization in the open-source MATLAB Reservoir Simulation Toolbox (MRST), and compare the methods in terms of history-matching quality and computational efficiency. We show complementary advantages of both ES-MDA and gradient-based optimization. ES-MDA is suitable when an exact gradient is not available and provides a satisfactory forecast of future production that often envelops the reference history data. On the other hand, gradient-based optimization is efficient if the exact gradient is available, as it then requires a low number of model evaluations. If the exact gradient is not available, using an approximate gradient or ES-MDA are good alternatives and give equivalent results in terms of computational cost and quality predictions.
Coupling a Geomechanical Reservoir and Fracturing Simulator with a Wellbore Model for Horizontal Injection Wells
Authors: Zheng Shuang , Sharma Mukul 
Published: October 2021

Abstract
Reservoir cooling during waterflooding or waste-water injection can significantly alter the reservoir stress field by thermo-poro-elastic effects. Colloidal particles in the injected water decrease the matrix permeability and buildup the injection pressure. Fractures may initiate and propagate from injectors. These fractures are of great concern for both environmental reasons and strong influence on reservoir sweep and oil recovery. This paper introduces methods to fully couple reservoir simulation with wellbore flow models in fractured injection wells.
A method to fully couple reservoir-fracture-wellbore models was developed. Fluid flow, solid mechanics, energy balance, fracture propagation, and particle filtration are modelled in the reservoir, fracture and wellbore domains. Effective stress in the reservoir domain is altered by thermo-poro-elastic effects during cold water injection. Fracture initiation and propagation induced by thermal and filtration effects is modelled in the fracture domain. Particle filtration on the borehole and fracture surfaces is modelled by matrix permeability reduction and filter cake build-up. Leakoff through the borehole and fracture surface is balanced dynamically. The coupled nonlinear system of equations is solved implicitly using Newton-Raphson method.
We validate our model with existing analytical solutions for simple cases. We show how the poro-elasticity effect, thermo-elasticity effect, water quality, and wellbore open/cased conditions influence well injectivity, induced fracture propagation and flow distribution. Simulation results show that water quality and thermal effects control fluid leak-off and fracture growth. While it is difficult to predict the exact location of fracture initiation due to reservoir heterogeneity, we proposed a reasonable method to handle fracture initiation without predefined fracture location in the water injection applications. In open-hole completions, this may lead to "thief" fractures propagating deep into the reservoir. Thermal stress changes in the injection zone are shown to be significant because of the combined effect of forced convection, heat conduction and poroelasticity. The accurate predictions of thermal stress in different reservoir layers allow us to study fracture height growth and containment numerically for the first time. We show that controlling the temperature and the injection water quality is also found to be an effective way to ensure fracture containment.
Modeling Acid Fracturing Treatments with Multi-Stage Alternating Injection of Pad and Acid Fluids
Authors: Dong Rencheng , Wheeler Mary F. , Su Hang , Ma Kang 
Published: October 2021

Abstract
Acid fracturing technique is widely applied to stimulate the productivity of carbonate reservoirs. The acid-fracture conductivity is created by non-uniform acid etching on fracture surfaces. Heterogeneous mineral distribution of carbonate reservoirs can lead to non-uniform acid etching during acid fracturing treatments. In addition, the non-uniform acid etching can be enhanced by the viscous fingering mechanism. For low-perm carbonate reservoirs, by multi-stage alternating injection of a low-viscosity acid and a high-viscosity polymer pad fluid during acid fracturing, the acid tends to form viscous fingers and etch fracture surfaces non-uniformly. To accurately predict the acid-fracture conductivity, this paper developed a 3D acid fracturing model to compute the rough acid fracture geometry induced by multi-stage alternating injection of pad and acid fluids. Based on the developed numerical simulator, we investigated the effects of viscous fingering, perforation design and stage period on the acid etching process. Compared with single-stage acid injection, multi-stage alternating injection of pad and acid fluids leads to narrower and longer acid-etched channels.
The MicroRNA miR-18a Links Proliferation and Inflammation During Photoreceptor Regeneration in the Injured Zebrafish Retina
Authors: Magner Evin , Sandoval-Sanchez Pamela , Kramer Ashley C , Thummel Ryan , Hitchcock Peter F , Taylor Scott 
Published: October 2021

Abstract
In mammals, photoreceptor loss causes permanent blindness, but in zebrafish (Danio rerio), photoreceptor loss reprograms Müller glia to function as stem cells, producing progenitors that fully regenerate photoreceptors. MicroRNAs (miRNAs) regulate neurogenesis in the CNS, but the roles of miRNAs in injury-induced neuronal regeneration are largely unknown. In the embryonic zebrafish retina, miRNA miR-18a regulates photoreceptor differentiation. The purpose of the current study was to determine in zebrafish the function of miR-18a during injury-induced photoreceptor regeneration. RT-qPCR, in-situ hybridization and immunohistochemistry showed that miR-18a expression increases throughout the retina by 1-day post-injury (dpi) and increases through 5 dpi. To test miR-18a function during photoreceptor regeneration, we used homozygous miR-18a mutants (miR-18ami5012), and knocked down miR-18a with morpholino oligonucleotides. During photoreceptor regeneration, miR-18ami5012 retinas have fewer mature photoreceptors than WT at 7 and 10 dpi, but there is no difference at 14 dpi, indicating that photoreceptor regeneration is delayed. Labeling dividing cells with bromodeoxyuridine (BrdU) showed that at 7 and 10 dpi, there are excess Müller glia-derived progenitors in both mutants and morphants, indicating that miR-18a negatively regulates injury-induced proliferation. Tracing BrdU-labeled cells showed that in miR-18ami5012 retinas excess progenitors migrate to other retinal layers in addition to the photoreceptor layer. Inflammation is critical for photoreceptor regeneration, and RT-qPCR showed that in miR-18ami5012 retinas, inflammatory gene expression and microglia activation are prolonged. Suppressing inflammation with dexamethasone rescues the miR-18ami5012 phenotype. Together, these data show that during photoreceptor regeneration in zebrafish, miR-18a regulates proliferation and photoreceptor regeneration by regulating the inflammatory response.
Three-dimensional Hydrogels of Alginate/chitosan Semi-interpenetrating Polymer Networks and Nanocelluloses
Authors: Siqueira Priscila , de Lima Ana , Medeiros Felipe , Isaac Augusta , Novack Katia , Botaro Vagner , Siqueira Eder 
Published: October 2021

Abstract
The hydrogels are advanced materials used in biomedical applications during wound healing, controlled drug release and to prepare scaffolds. In this work are prepared hydrogels of alginate/chitosan (Alg/Ch) semi-interpenetrating polymer networks (semi-IPN’s) and nanocelluloses. The hydrogels after preparation by freeze drying are namely simply as gels. The cellulose nanocrystals (CNC’s) are obtained from acid hydrolysis of bleached Eucalyptus pulps and oxidized cellulose nanocrystals (CNCT’s) prepared by (2,2,6,6-tetramethylpiperidin-1-yl)oxyl radical catalyzed reaction as known as TEMPO reaction. The cellulose nanofibers (NFC’s) are obtained from mechanical shearing of cellulose pulps and oxidized NFC’s by TEMPO-mediated reaction (NFCT’s). The nanocellulose suspension and gels are characterized by FTIR at ATR mode, TGA, XRD, TEM, SEM, X-ray computed microtomography (micro-CT) and DMTA. The addition of CNC’s, NFC’s, CNCT’s or NFCT’s in the microstructure of gels increases their dimensional stabilities. The best results are obtained when CNCT’s and NFCT’s are added. The mechanical properties and dimensional stability of Alg/Ch semi-IPN’s increase after controlled thermal post-treatment. The heating during thermal post-treatment boosts the physicochemical interactions in the microstructures of semi-IPN’s. The biological assays show biocompatibility of fibroblast cells on the substrates, and differentiation and proliferation up seven days. The optimized mechanical properties, dimensional stability and biocompatibility of the gels studied in this work are important parameters for potential biomedical applications of these biomaterials.
Management Algorithm of External Fixation in Lower Leg Arterial Injury for Limb Salvages
Authors: Jin Lei , Zhang Song , Liu Motao , Zhang Yuxuan , Lin Xin , Feng Dehong , Hu Kejia 
Published: October 2021

Abstract
Purpose: The purpose of this study was to review the roles of using external fixation to rescue the patients who sustained arterial injuries in the lower legs.Methods: Demographics, surgical treatment and outcomes in 88 patients with lower leg arterial injuries treated by external fixation at two trauma centers from 2009 to 2018 were reviewed. The primary outcome was the rate of successful lower leg salvage, while secondary outcomes were complications and functional recovery.Results:80 patients (90 legs) maintained a successful lower leg salvage. The patients were followed up for an average of 15.5±5.5 months. 6 patients (8 pins) experienced pin-tract infection, pins loosening happened in 2 patients (4 pins), 7 patients (7 legs) developed wound superficial infection, 3 patients (3 legs) with a deep infection developed osteomyelitis, 16 patients (17 legs) suffered the bone nonunion or bone defect. The average healing time of fracture was 5.6±4.3months. The maintain of external fixation average time was 5.8±3.6 months. Conclusion: With correctly judging the condition of limb ischemia, mastering reasonably the operation indications, and preventing complications, good clinical effects can be achieved when external fixation is used.Level of evidence: Retrospective cohort, level IV.
Temporal and Spatial Distribution Characteristics of Drought and Flood Considering the Influence of Underlying Surface in Hainan Island, Tropical Areas of China
Authors: Ye Changqing , Zou Yi , He Yanhu , Lin Youwen , Li Dan , Zhu Lirong 
Published: October 2021

Abstract
Most studies of temporal and spatial distribution characteristics of droughts and floods analysis were conducted only from the perspective of a single factor (precipitation), while ignoring the impact of the characteristics of the underlying surface on the formation of droughts and floods. Using the daily precipitation data of 88 meteorological stations in Hainan province from 1970 to 2019, the 30m resolution DEM data, land use dataset, etc, the precipitation Z index is used to evaluate the drought and flood levels in Hainan province. The analysis results were revised by underlying surface data to evaluate the spatiotemporal characteristics of the drought and flood area in Hainan province. The drought-prone areas and flood prone areas in Hainan province were divided, and on this basis, the set pair analysis method was used to identify the regions with alternating drought and flood areas in Hainan. The results show that the overall arid area shows an obvious downward trend, while the flood area presents an increasing trend. The drought-prone areas throughout the year are more concentrated in the northeast of Hainan Province, while flood prone areas are mainly distributed in the eastern coastal areas. The regions where drought and flood occur alternately are small but concentrated. The drought and flood prone areas and alternate drought and flood areas before and after the revision by the underlying surface were compared. It can be seen that the overall trend is relatively similar and obvious before and after the revision. The result of drought areas before revision is 20.43 times larger than that after revision. The flood prone areas before revision are 8.50 times larger than that after revision. The alternating drought and flood areas before underlying surface revision in spring and summer are 17.50 times larger than that after revision. Similarly, it is 48.64 times in summer and autumn, and 17.62 times in autumn and winter. Finally, combining climate and underlying surface factors, suggestions are put forward for drought and flood prevention.
Implementation of a client-accessible and multidisciplinary youth health record in the Netherlands; a mixed-methods process evaluation
Authors: Benjamins Janine , Duinkerken Jan-Gerrit , Jordaan Gerlinde , Koster Rianne , Canfijn Romay , de Vet Emely , Haveman-Nies Annemien 
Published: October 2021

Abstract
Background: Client-accessible patient records potentially contribute to patient-centered care by facilitating shared decision-making, enhancing interdisciplinary collaboration, and promoting patient’s autonomy. To achieve this, three Dutch organizations providing ‘care for youth’ developed an electronic patient record (EPR-Youth). EPR-Youth supports working processes of all three organizations and is fully accessible for adolescents and for parents of children aged 0-16 years. Co-creation was chosen as implementation approach for this e-Health intervention that not only intervenes with technology (hardware) but also transforms working processes (orgware) and professional behavior (software). Objective: to investigate the implementation process of EPR-Youth and to determine barriers and facilitators.Methods: a mixed methods design was used. To guide the process evaluation, Pfadenhauers’ Context and Implementation of Complex Interventions framework and Proctor’s theoretic framework on implementation were used to define implementation outcomes and describe setting and context. Target groups were parents, adolescents, professionals using EPR-Youth, and all stakeholders in the implementation process.Results: Barriers in the implementation process of EPR-Youth were the complexity of collaboration between stakeholders and the lack of clarity about leadership and project planning. Facilitating factors were clarifying the vision, setting deadlines, and a pioneering spirit.Acceptability of the client-portal was high among all users. Adoption of the client-portal was highest among parents of children aged 0-3 years and among higher educated parents.Professionals’ doubts about user-friendliness and about the match with vision and working processes were partly due to lack of knowledge of all system functionalities. Conclusion: The implementation of EPR-Youth, the first Dutch electronic patient record facilitating both preventive child health and youth care, was successful on ‘hardware’ level. To complete implementation on ‘software’ and ‘orgware’ level, client information needs attention, as well as training of professionals. Further research is needed to gain insight into barriers to access the client-portal. Although co-creation was an essential ingredient to reach project goals, situational leadership with more direction at the start and room for disruption is needed to guide this process.
The Controversial Role of Folic Acid on Diabetic Auditory Neuropathy
Authors: Doostkam Aida , Mirkhani Hossein , Iravani Kamyar , Karbalay-Doust Saied , Doosti Afsaneh , Nadimi Elham 
Published: October 2021

Abstract
PurposeDiabetic auditory neuropathy(DAN) is a common complication of diabetes that seriously affects the quality of life in patients. In this study, we investigate the role of folic acid in the treatment of DAN in an experimental rat model.MethodsThirty-two Sprague-Dawley rats were equally divided into 4 groups: group 1, normal; group 2, diabetic rats; group 3and 4, rats treated with folic acid (40 and 80 mg/kg, respectively). The tools we used in this study to investigate the effect of folic acid on DAN were auditory brain stem response, stereology methodfor estimation ofthe volume and number ofspiral ganglion,volume of stria vascularis, and spiral ligament, and measurement of homocysteine (HCY), malondealdehyde(MDA) and superoxide dismutase.ResultsOur study showed that folic acid treatment was not significantly effective in improving structural and functional disorders in DAN, despite its effect in reducing HCY and MDA as oxidative biomarkers.ConclusionFolic acid is not effective in relieving morphological and functional disorders in DAN.
Covid-19 Pandemic Impact in Pediatricians: Stress Factors and their Consequences
Authors: Lozón Ana Muñoz , García Arístides Rivas , Vives Leticia González , López María Cristina Muñoz , Blanco Ana Jové , LOYGORRI CLARA FERRERO GARCÍA- 
Published: October 2021

Abstract
Introduction: Previous studies have demonstrated that COVID-19 pandemic has had negative psychological consequences in healthcare professionals, however, few of them concentrate on pediatricians’ experience. The aim of this study is to evaluate anxiety among spanish pediatricians after the first COVID-19 wave as well as to identify possible risk factors. Material and Methods: A transversal and multicentric study of questionnaires was designed. Demographic, socio-familiar and laboral information was collected, as well as emotional self perception information, psychosomatic symptoms, tobacco consumption and psychotropic treatment. Participants fulfilled the State-Trait Anxiety Inventory (STAI). Results: 440 questionnaires were registered. Globally, 42.2% of the participants expressed moderate-intense anxiety symptomatology according to the Anxiety-State scale and 26.8% in the Anxiety-Trait scale. Domiciliary isolation was associated with a higher score in both scales. Changes in the cohabitants’ working situation was associated with a higher score in the Anxiety-State scale. With respect to the psychological impact perceived by participants during pandemic situation, 41.1% classified it as mild, 50% as moderate, and 8.9% as severe. Up to 71.8% of the participants suffered psychosomatic symptoms. A linear association was found between suffering from multiple psychosomatic symptoms and higher scores in both scales. Conclusions: After the first pandemic wave pediatricians have suffered anxiety, which has caused physical and emotional discomfort. Personal circumstances have been the main worry of medical staff. Coexistence of various psychosomatic symptoms has been associated with higher anxiety levels.