bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flipped laboratory classes: Student performance and perceptions in undergraduate food science and technology
Authors: Mshayisa Vusi Vincent , Basitere Moses 
Published: November 2021

AbstractIn STEM (science, technology, engineering, and mathematics) courses, undergraduate laboratory classes are vital for students to develop competencies such as critical observation, collaboration, critical thinking, technical, and problem‐solving skills. Thus, for students to successfully acquire these competencies, preparation for laboratory classes is essential. This study aimed to explore the students' performance and perceptions of online pre‐laboratory videos and quizzes in undergraduate food science and technology. Quantitative data on student usage statistics of the videos, student performance in online quizzes and practical reports scores and student perceptions were analysed to provide a detailed perspective of the course. The students' performance was above 60% in all pre‐lab quizzes for both the 2018 and 2019 cohorts. The average pre‐lab video views were higher in the 2019 cohorts compared to the 2018 cohort. The majority of the students felt that the topics were well explained in the videos (M = 4.25 ± 0.84) and it was easy to learn from the videos (M = 4.31 ± 0.76). In terms of students perceptions, a strong positive correlations were found between course organisation and motivation and self‐efficacy (r = 0.86, p < 0.05); course engagement and motivation and self‐efficacy (r = 0.82, p < 0.05). The strongest positive correlation was between course organisation and online engagement (r = 0.95, p < 0.05). The results of this study suggest that the introduction of multimodal/digital preparation resources (pre‐lab videos and online quizzes) was positively received and benefited the students. Students have engaged enthusiastically with these resources and completed the majority of the tasks set. These findings will further expand research directed towards student perception of the lab experience and aid in the adaptation of food science and technology curriculums to accommodate both student and university needs.
The dynamic effects of price support policy on price volatility: The case of the rice market in China
Authors: Li Jian , Chavas Jean‐Paul , Li Chongguang 
Published: November 2021

AbstractThis study examines the economic and welfare effects of a commodity price support policy. It conceptually and empirically evaluates the effects of the domestic pricing policy on the distribution of commodity prices, with an application to the price support program in the Chinese rice market. The empirical analysis relies on a Censored Quantile Autoregression (CQAR) model, which provides a refined and flexible representation of the evolving distribution of prices under a price support program. Based on monthly data over the period 2000–2018, we develop and estimate an econometric model documenting the price effects of policy interventions. We study how a price support program affects price distribution both in the short term and long term. We find that such a program has reduced the domestic rice price volatility, evidenced by lowered variation and increased right‐skewness of the price distribution. We also show how China's rice programs' high price support level during the period 2008–2015 caused significant censoring effects and price enhancement with adverse impacts on consumer welfare across all income levels. We further examine alternative situations where a moderate price support level can reduce the long‐term mean price without generating consumer welfare losses. Our analysis and findings have implications for the implementation of agricultural price support policies in many developing countries.
Screening and surveillance for gastric cancer: Does family history play an important role in shaping our strategy?
Authors: Luu Mai Ngoc , Quach Duc Trong , Hiyama Toru 
Published: November 2021

AbstractFamily history is an important risk factor of gastric cancer. No guidelines have been developed that target gastric cancer with a family history; only hereditary familial gastric cancer is targeted. We review the available evidence regarding the familial aggregation mechanisms of gastric cancer and a strategy of screening and surveillance for gastric cancer in individuals with a positive family history of the disease. As there is a synergic effect of Helicobacter pylori infection and family history on the increased risk of gastric cancer, Helicobacter pylori eradication should be considered in all infected individuals with a family history of gastric cancer. Currently, there is weak evidence indicating that suitable timing to initiate eradication therapy is at the age of 20, when precancerous lesions, including significant gastric atrophy and intestinal metaplasia, have not been established. Reasonable timing to initiate screening for gastric cancer in individuals with a family history of gastric cancer is 10 years prior to the age of onset of gastric cancer in affected relatives. A 2‐year surveillance interval, instead of the 3‐year interval recommended in the present guidelines, may be better to detect early gastric cancer in those individuals who have already developed precancerous gastric lesions.
Proportional inverse Gaussian distribution: A new tool for analysing continuous proportional data
Authors: Liu Pengyi , Tian Guo‐Liang , Yuen Kam Chuen , Zhang Chi , Tang Man‐Lai 
Published: November 2021

SummaryOutcomes in the form of rates, fractions, proportions and percentages often appear in various fields. Existing beta and simplex distributions are frequently unable to exhibit satisfactory performances in fitting such continuous data. This paper aims to develop the normalised inverse Gaussian (N‐IG) distribution proposed by Lijoi, Mena & Prünster (2005, Journal of the American Statistical Association, 100, 1278–1291) as a new tool for analysing continuous proportional data in (0,1) and renames the N‐IG as proportional inverse Gaussian (PIG) distribution. Our main contributions include: (i) To overcome the difficulty of an integral in the PIG density function, we propose a novel minorisation–maximisation (MM) algorithm via the continuous version of Jensen's inequality to calculate the maximum likelihood estimates of the parameters in the PIG distribution; (ii) We also develop an MM algorithm aided by the gradient descent algorithm for the PIG regression model, which allows us to explore the relationship between a set of covariates with the mean parameter; (iii) Both the comparative studies and the real data analyses show that the PIG distribution is better when comparing with the beta and simplex distributions in terms of the AIC, the Cramér–von Mises and the Kolmogorov–Smirnov tests. In addition, bootstrap confidence intervals and testing hypothesis on the symmetry of the PIG density are also presented. Simulation studies are conducted and the hospital stay data of Barcelona in 1988 and 1990 are analysed to illustrate the proposed methods.
Direct oral anticoagulants versus vitamin K antagonists in epistaxis patients: A systematic review and meta‐analysis
Authors: Stanković Petar , Hoch Stephan , Rudhart Stefan , Obradović Danilo , Dagres Nikolaos , Wilhelm Thomas 
Published: November 2021

AbstractObjectiveEpistaxis is the most common otolaryngological emergency and up to one third of patients in treated on an inpatient basis take oral anticoagulants (OAC). Direct oral anticoagulants (DOAC), an OAC subgroup, have been on the market since 2010 and are being increasingly prescribed due to the cardiological and haematological guidelines that favour them over vitamin K antagonists (VKA), the older of the OAC subgroups. The present study aims to investigate which subgroup of epistaxis patients taking OACs has a more favourable outcome.Design/settingA systematic review and meta‐analysis were performed according to the PRISMA 2020 statement using the PubMed and Cochrane Library databases. Continuous data were analysed and standardised mean difference (SMD) was calculated according to Hedges' g. Dichotomous data were analysed, and the Mantel‐Haenszel method was applied to establish the odds ratio (OR). Heterogeneity was assessed according to the I
2 statistics.Main outcome/resultsA total of eight reports covering 1390 patients were included in the final synthesis. The pooled analysis demonstrated significantly shorter hospital stays in the DOAC group (SMD = −0.22, 95% CI−0.42 to −0.02, p = .03) and a significantly higher rate of posterior bleeding in the VKA group (OR = .39, 95% CI 0.23 to 0.68, p = .001). No statistically significant differences with regard to recurrence rates, admission rates, the need for transfusion or surgical intervention (p = .57, .12, .57 and .38 respectively) were found.ConclusionAccording to this meta‐analysis, epistaxis patients taking DOACs have a more favourable outcome than patients taking VKAs.
The COVID‐19 Pandemic and Consumption of Food away from Home: Evidence from High‐frequency Restaurant Transaction Data
Authors: Zhu Chen , Lopez Rigoberto A. , Gao Yuan , Liu Xiaoou 
Published: November 2021

AbstractThis article investigates how the COVID‐19 pandemic and related public health measures affected the consumption of food away from home (FAFH) among Chinese consumers. We obtained access to the complete sales records from a major restaurant chain in China, for 111 sites located in 12 cities, covering over 5.6 million high‐frequency dining transactions made between 1 January 2019 and 31 December 2020. By applying a high‐dimensional fixed‐effects model, we found that, on average, consumers spent more and ordered more calories (as well as carbohydrates, protein, fat, and sodium) after the COVID‐19 outbreak than in the pre‐COVID‐19 period. Our results do not support the hypothesis that COVID‐19 led to healthier eating behaviors during and after the pandemic. Our results underline the importance of nutrition education and awareness programs to mitigate unhealthy eating habits generated by the pandemic and of the continued role of FAFH after the pandemic.
The Impacts of Trade Restrictions on World Agricultural Price Volatility during the COVID‐19 Pandemic
Authors: Yan Wenshou , Cai Yan , Lin Faqin , Ambaw Dessie Tarko 
Published: November 2021

AbstractDuring the COVID‐19 pandemic, countries applied trade restrictions to insulate their domestic markets from the world market. However, these trade policies could have amplified international market price fluctuations. This paper explores the effects of trade restrictions on international agricultural price volatility. A theoretical model is developed to quantify how trade policies amplify the initial shock. Using panel data covering 71 countries from January 2020 to July 2021, we examine empirically the effects of trade policies on world agricultural price volatility. The results show that trade distortions further induced volatility of world agricultural prices by around 22 percent during the COVID‐19 pandemic. The multiplier effects are much more substantial in agricultural exporting countries than in importing countries. Large countries like China and the US could make significant contributions to stabilizing world prices by limiting the extent of unilateral trade policy interventions.
Charakteristika von Dermatomyositis‐Patienten mit und ohne Malignom‐Assoziation
Authors: Lauinger Julia , Ghoreschi Kamran , Volc Sebastian 
Published: November 2021

ZusammenfassungHintergrundDie Dermatomyositis gehört zur Gruppe der seltenen, idiopathischen, inflammatorischen Myositiden. Für die paraneoplastische Form der Dermatomyositis wurde in der Vergangenheit ein Zusammenhang mit Malignomen erkannt. Faktoren, die für eine Malignom‐Assoziation sprechen, werden bis heute untersucht.Patienten und MethodikEs wurden retrospektiv über einen Zeitraum von 15 Jahren die Daten von 63 Patienten mit Dermatomyositis analysiert.ErgebnisseFolgende Faktoren gaben einen Hinweis für eine Dermatomyositis mit Malignom‐Assoziation: ein höheres Patientenalter (> 52 Jahre [P = 0,001], > 65 Jahre [P = 0,002], ≥ 75 Jahre [P = 0,002]), eine kürzere Zeit zwischen Erstmanifestation und Erstdiagnose (Malignom‐Gruppe: 59 Tage vs. Nicht‐Malignom‐Gruppe: 137 Tage [P = 0,022]), eine Hautbeteiligung in Form von Gottron‐Zeichen (P = 0,045), zentrofazialen Erythemen (P = 0,036) oder typischen Erythemen an den Ober‐/Unterarmen (P = 0,019), eine oropharyngeale Beteiligung (P = 0,015) und eine GPT‐Erhöhung (P = 0,031). Folgende Faktoren sprachen eher gegen eine Malignom‐Assoziation: ein jüngeres Patientenalter (≤ 52 Jahre [P = 0,001], 40–65 Jahre [P = 0,045]) und Juckreiz (P = 0,026).SchlussfolgerungenIn der Literatur finden sich heterogene Ergebnisse zu den genannten Faktoren hinsichtlich ihrer Eignung als Marker für eine Malignom‐Assoziation. Erschwert ist die Faktorenfindung aufgrund kleiner Studienpopulationen, wenigen prospektiven und kontrollierten Studien, die Einordnung von Populationen als Myositis‐Patienten ohne Differenzierung und eine inkonsistente Verwendung der Nomenklatur. Mit unserer Studie wollen wir einen wichtigen Beitrag zur Identifizierung von Risikofaktoren bei Dermatomyositis mit Malignom‐Assoziation leisten.
Hide‐and‐seek: Neurotropes Plattenepithelkarzinom der periorbitalen Region – eine Fallserie und Übersichtsarbeit aktueller Literatur
Authors: Morandi Evi M. , Rauchenwald Tina , Puelzl Petra , Zelger Bernhard W. , Zelger Bettina G. , Henninger Benjamin , Pierer Gerhard , Wolfram Dolores 
Published: November 2021

ZusammenfassungDas Plattenepithelkarzinom ist nach dem Basalzellkarzinom das zweithäufigste Malignom der Haut und wird vorwiegend an sonnenexponierten Stellen wie der Gesichtshaut diagnostiziert. Diese meist lokal destruktiv wachsende Malignität kann durchaus auch invasives Wachstumsverhalten, wie perineurale Ausbreitungsmechanismen, aufweisen. Das Plattenepithelkarzinom der periorbitalen Region ist in bis zu 14 % der Fälle mit perineuraler Invasion assoziiert. Vor allem in diesem Bereich birgt die anatomische Nähe zu den Hirnnerven das Risiko einer Progression Richtung zentrales Nervensystem, was mit einer schlechteren Prognose assoziiert ist. Der klinisch unauffällige Charakter dieser Entität resultiert oft in einer Verzögerung der definitiven Diagnosestellung, wodurch die vollständige Resektion und anschließende Rekonstruktion erschwert werden. Eine aufmerksame klinische Evaluierung kann bereits vor Erlangen histologischer Befunde Hinweise für ein perineurales Wachstum liefern.Neben fünf herausfordernden Fällen analysiert diese Arbeit Risikofaktoren, klinische als auch histologische Merkmale und Behandlungsoptionen des periorbitalen Plattenepithelkarzinoms mit perineuraler Invasion.
Arzneimittelexantheme unter modernen zielgerichteten Therapien – Immuncheckpoint‐ und EGFR‐Inhibitoren
Authors: Pospischil Isabella , Hoetzenecker Wolfram 
Published: November 2021

ZusammenfassungDer zunehmende Einsatz moderner zielgerichteter Therapien führt dazu, dass Dermatologen stetig mit neuartigen kutanen Nebenwirkungen dieser Substanzen konfrontiert werden. Eine rasche Diagnose und Therapie sind notwendig, um die planmäßige Fortführung der onkologischen Therapie zu ermöglichen und eine Beeinträchtigung der Lebensqualität der Patienten zu verhindern. Immuncheckpoint‐ und EGFR‐Inhibitoren sind häufig eingesetzte zielgerichtete Therapien mit spezifischen kutanen Nebenwirkungsspektren. Exanthematische Hautveränderungen stellen hierbei eine besondere diagnostische Herausforderung dar. Immuncheckpoint‐Inhibitoren können vielfältige immunvermittelte kutane Nebenwirkungen hervorrufen; am häufigsten sind dies makulopapulöse, lichenoide oder psoriasiforme Exantheme. Das Auftreten bullöse Autoimmundermatosen und Kollagenose‐assoziierter Exantheme ist möglich. Bei atypischen, ausgeprägten oder therapieresistenten exanthematischen Hautveränderungen ist eine dermatologische Abklärung inklusive Hautbiopsie zur genauen Einordnung indiziert. Die Hauptsäule der Therapie stellen topische und systemische Glukokortikoide dar. Unter EGFR‐Inhibitor‐Therapie sind papulopustulöse Exantheme die häufigste kutane Nebenwirkung, die je nach Substanz bei bis zu 90 % der Patienten innerhalb der ersten beiden Therapiewochen auftreten. Neben topischen Antibiotika und Glukokortikoiden sind systemische Tetrazykline die Therapie der ersten Wahl und können auch prophylaktisch eingesetzt werden.
Natural toxins leached from Eucalyptus globulus plantations affect the development and life‐history of anuran tadpoles
Authors: Iglesias‐Carrasco Maider , Cabido Carlos , Ord Terry J. 
Published: November 2021

Abstract

Rapid human‐induced transformation of habitats is presenting organisms with challenging novel environmental conditions. Nowadays, extensive areas of the world are covered by exotic plantations, and among these, eucalypt plantations stand out for their worldwide occurrence. These novel environments probably threaten the persistence of native species, with several studies reporting biodiversity losses in these transformed areas. However, the effects of such habitat alteration on life‐history traits that potentially constrain the ecology of individuals have been poorly explored.

In a mesocosm experiment, we exposed tadpoles of three anuran species (Rana temporaria, Alytes obstetricans, and Pelophylax perezi) to the leachates of natural oak trees and exotic eucalypt trees to explore how the transformation of natural forests into eucalypt plantation affects the expression of behavioural and morphological traits and immune response.

While anti‐predatory responses appeared not to be impacted by leachate type, tadpoles exposed to eucalypt leachates differed in morphology and growth, and exhibited weaker immune responses and smaller size at metamorphosis than those exposed to oak leachates. Some of the responses were also species‐specific, suggesting that some species are likely to be more sensitive than others to novel chemicals.

We conclude that the poor quality of eucalypt leaf litter (e.g., its low nutrient content), low amount of food (e.g., periphyton), and the presence of toxic detritus and leachates can have important stress‐related consequences for the critical early stages of development in anurans.
Effect of dispersants on structural integrity of 3D printed ceramics
Authors: Kim Jeehwan , Choi Yeong‐Jin , Gal Chang Woo , Park Honghyun , Yoon Seog‐Young , Yun Hui‐suk 
Published: November 2021

AbstractCeramic 3D printing based on stereolithography is an excellent alternative to overcome drawbacks of conventional subtractive manufacturing for 3D shape control. Optimization of photocurable ceramic slurry is one of the most essential conditions to achieve favorable 3D printed structures using SL. Homogeneity of ceramic particle dispersion in photocurable resin is particularly important to optimize ceramic suspension. Dispersant plays a significant role in increasing homogeneity. Dispersant in photocurable ceramic resin has an additional effect on photocurability and integrity of 3D printed green body. We herein discuss how dispersants influence 3D printing conditions based on stereolithography using various commercially available dispersants of BYK series such as BYK103, BYK111, BYK180, BYK182, and BYK2001. Both BYK111 and BYK180 showed better performances than others because of their lower volatilities under general temperature condition during a printing process. Both solubility and decomposition temperature of dispersants largely influenced the structural quality after washing and debinding processes. This study provides worthy information to design photocurable ceramic suspension for various types of ceramic materials.
Vers des relations collectives du travail inclusives: une sélection d'articles de laRevue internationale du Travailau cours du siècle écoulé
Authors: BOSCH Gerhard 
Published: November 2021

RésuméLes relations collectives du travail, ou relations professionnelles, sont fondées sur des droits spécifiques qui ne peuvent être exercés que par des organes de représentation des salariés, et non par des salariés à titre individuel. Parmi les nombreuses publications sur le sujet parues dans laRevue internationale du Travailau cours des cent dernières années, quinze contributions ont été sélectionnées pour figurer dans ce numéro du centenaire. L'un des critères de sélection a été l'accent mis sur le renforcement de l'inclusion – c'est‐à‐dire l'extension de la protection offerte au plus grand nombre possible de personnes et pas seulement à des catégories privilégiées. Des relations professionnelles inclusives sont une condition préalable au recul des discriminations sur le marché du travail et au caractère universel du travail décent.
Factors associated with ocular surface disease and severity in adults with atopic dermatitis: a nationwide survey
Authors: Rønnstad A.T.M. , Hansen P.M. , Halling A.S. , Egeberg A. , Kolko M. , Heegaard S. , Thyssen J.P. 
Published: November 2021

AbstractBackgroundOcular surface diseases (OSDs), including conjunctivitis and blepharitis, are common in atopic dermatitis (AD) patients, but the magnitude and patient characteristics are unclear.ObjectivesTo examine the prevalence of OSDs in adults with AD and identify patient characteristics and risk factors.MethodsWe designed a cross‐sectional questionnaire‐based survey and sent it via a secure public mail to all adult Danes with a hospital diagnosis of AD (ICD‐10 code L20.x) registered in the National Patient Register (n = 16 718) between 2000 and 2019 and 7044 (42%) participated. Primary outcomes were OSDs and severity according to Ocular Surface Disease Index (OSDI). Adjusted odds ratios (aOR) were calculated with 95% confidence intervals (CIs) using logistic regression models.ResultsRespondents were mostly females and middle‐aged (67.4%, mean [SD] age, 39.0 [15.5] years). Based on Patient‐Oriented SCORing Atopic Dermatitis 49% had mild AD, 35% moderate, 10% severe and in 6% AD was inactive; 44.3% reported physician‐diagnosed asthma bronchiale and 55.8% rhinitis. The lifetime prevalence of OSDs was 66.6% for conjunctivitis, 63.5% for hordeolum, 11.0% for blepharitis, 9.7% for keratitis, 2.0% for pterygium, 1.5% for symblepharon, 1.1% for keratoconus and 12.7% reported current conjunctivitis. Factors associated with lifetime occurrence of conjunctivitis included mild, moderate, and severe AD (aOR = 1.48 [95% CI, 1.02–2.14], aOR = 1.73 [95% CI, 1.19–2.53], aOR = 2.17 [95% CI, 1.42–3.21]), asthma bronchiale and rhinitis (aOR = 1.76 [95% CI, 1.49–2.07]), childhood‐onset of AD (aOR = 1.34 [95% CI, 1.16–1.56]) and systemic AD treatment (aOR = 1.27 [95% CI, 1.08–1.50]). Use of soft and hard contact lenses (aOR = 2.15 [95% CI, 1.65–2.80], aOR = 3.35 [95% CI, 1.62–6.92]) were associated with lifetime occurrence of keratitis. Moderate and severe AD, asthma bronchiale and rhinitis were also associated with a higher OSDI level.ConclusionsThis study identified important patient factors associated with OSDs. Clinicians should be attentive of ocular signs and symptoms in AD patients and ask about these.