bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early Stopping in Experimentation With Real-Time Functional Magnetic Resonance Imaging Using a Modified Sequential Probability Ratio Test
Authors: Carr Sarah J. A. , Chen Weicong , Fondran Jeremy , Friel Harry , Sanchez-Gonzalez Javier , Zhang Jing , Tatsuoka Curtis 
Published: November 2021

Introduction: Functional magnetic resonance imaging (fMRI) often involves long scanning durations to ensure the associated brain activity can be detected. However, excessive experimentation can lead to many undesirable effects, such as from learning and/or fatigue effects, discomfort for the subject, excessive motion artifacts and loss of sustained attention on task. Overly long experimentation can thus have a detrimental effect on signal quality and accurate voxel activation detection. Here, we propose dynamic experimentation with real-time fMRI using a novel statistically driven approach that invokes early stopping when sufficient statistical evidence for assessing the task-related activation is observed.Methods: Voxel-level sequential probability ratio test (SPRT) statistics based on general linear models (GLMs) were implemented on fMRI scans of a mathematical 1-back task from 12 healthy teenage subjects and 11 teenage subjects born extremely preterm (EPT). This approach is based on likelihood ratios and allows for systematic early stopping based on target statistical error thresholds. We adopt a two-stage estimation approach that allows for accurate estimates of GLM parameters before stopping is considered. Early stopping performance is reported for different first stage lengths, and activation results are compared with full durations. Finally, group comparisons are conducted with both early stopped and full duration scan data. Numerical parallelization was employed to facilitate completion of computations involving a new scan within every repetition time (TR).Results: Use of SPRT demonstrates the feasibility and efficiency gains of automated early stopping, with comparable activation detection as with full protocols. Dynamic stopping of stimulus administration was achieved in around half of subjects, with typical time savings of up to 33% (4 min on a 12 min scan). A group analysis produced similar patterns of activity for control subjects between early stopping and full duration scans. The EPT group, individually, demonstrated more variability in location and extent of the activations compared to the normal term control group. This was apparent in the EPT group results, reflected by fewer and smaller clusters.Conclusion: A systematic statistical approach for early stopping with real-time fMRI experimentation has been implemented. This dynamic approach has promise for reducing subject burden and fatigue effects.
Comprehensive Analysis of m6A RNA Methylation Regulators in the Prognosis and Immune Microenvironment of Multiple Myeloma
Authors: Liu Rui , Shen Ying , Hu Jinsong , Wang Xiaman , Wu Dong , Zhai Meng , Bai Ju , He Aili 
Published: November 2021

BackgroundN6-methyladenosine is the most abundant RNA modification, which plays a prominent role in various biology processes, including tumorigenesis and immune regulation. Multiple myeloma (MM) is the second most frequent hematological malignancy.Materials and MethodsTwenty-two m6A RNA methylation regulators were analyzed between MM patients and normal samples. Kaplan–Meier survival analysis and least absolute shrinkage and selection operator (LASSO) Cox regression analysis were employed to construct the risk signature model. Receiver operation characteristic (ROC) curves were used to verify the prognostic and diagnostic efficiency. Immune infiltration level was evaluated by ESTIMATE algorithm and immune-related single-sample gene set enrichment analysis (ssGSEA).ResultsHigh expression of HNRNPC, HNRNPA2B1, and YTHDF2 and low expression of ZC3H13 were associated with poor survival. Based on these four genes, a prognostic risk signature model was established. Multivariate Cox regression analysis demonstrated that the risk score was an independent prognostic factor of MM. Enrichment analysis showed that cell cycle, immune response, MYC, proteasome, and unfold protein reaction were enriched in high-risk MM patients. Furthermore, patients with higher risk score exhibited lower immune scores and lower immune infiltration level.ConclusionThe m6A-based prognostic risk score accurately and robustly predicts the survival of MM patients and is associated with the immune infiltration level, which complements current prediction models and enhances our cognition of immune infiltration.
Case Report: Superficial Circumflex Iliac Artery Perforator Flap for Tongue Reconstruction Following the Hemiglossectomy
Authors: Fang Yihong , Ouyang Qiming , Zheng Zhi , Wang Jin 
Published: November 2021

Objective: Therapeutic evaluation of applying superficial circumflex iliac artery perforator (SCIP) flap in tongue reconstruction after hemiglossectomy.Methods: We retrospectively collected a total number of 14 patients who received SCIP flap reconstruction for tongue defects at the Fujian Medical University affiliated Union Hospital, between November 2016 and November 2020. We evaluated the clinical features of the flap, analyzed the postoperative functions and esthetic effects after 6 months of the tongue reconstruction.Results: All the SCIP flaps survived successfully after the operation, the recipient site tongue bodies were well reconstructed 6 months after the surgery. Patient speech and swallowing functions were well recovered during the follow-up. The scars in the donor site were concealed with limited numbness.Conclusions: With the advantages of the hidden donor site and aesthetic benefits, the SCIP flap is a reliable option for the reconstruction of the tongue defect after hemiglossectomy.
Population-Based Survival Analysis of Patients With Limb Rhabdomyosarcoma and Metastasis at Diagnosis
Authors: Yang Chunying , Wang Haiqing , Niu Feng , Yao Lufeng 
Published: November 2021

Purpose: Given the poor prognosis and the relative rarity of patients diagnosed with limb rhabdomyosarcoma (LRMS) and metastasis at diagnosis, we performed this study to reveal distinctive clinical features and evaluated prognostic factors of this special population in order to provide appropriate treatment.Patients and Methods: We carried out retrospective research of patients diagnosed with LRMS and metastasis from 1975 to 2016 using the Surveillance, Epidemiology, and End Results (SEER) program database. Survival curves were generated by applying the Kaplan–Meier method. In terms of evaluating and determining independent predictors of survival, we conducted univariate and multivariate survival analyses using the Cox proportional hazard regression model.Results: This retrospective analysis contained a series of 245 patients with metastatic LRMS, with male predominance (male vs. female, 1.6:1). Nearly half of the patients were diagnosed with alveolar rhabdomyosarcoma (44.9%). According to the results of the univariate and multivariate analyses, younger age, tumor subtype, and radiotherapy were found to be significantly associated with improved overall survival (OS) and cause-specific survival (CSS).Conclusions: Patients with LRMS and metastasis at diagnosis experienced a quite poor prognosis. Age at diagnosis, tumor subtype, and radiotherapy can help clinicians to better estimate the prognosis. This study indicated that local radiotherapy can provide a survival benefit.
Graphic Trauma
Authors: Diedrich Lisa 
Published: November 2021

In this essay, I explore examples of what I call graphic trauma and the processof drawing as a form of working through the experience and event of sexual violence. I contend that comics and graphic narratives are a medium well-suited for rendering trauma, and the trauma of sexual violence in particular, as I show in an analysis of Una’s graphic narrative Becoming Unbecoming and Chanel Miller’s animated short film I Am With You. I argue that for both artists, drawing becomes a form of consciousness-raising, a collaborative feminist practice of memory
work that attempts to create conditions – formal, therapeutic, and political – for women to say #MeToo and “we.” In my readings of Una’s and Miller’s draw-ing as working through sexual violence, I also demonstrate close verbal/visual description as a practice of care that keeps the testimony moving, drawing out the feminist practice of memory work in time and space and across modalities. A brief coda at the end of the essay offers an image of a hybrid figure from Miller’s graphic iconography and a concept and practice she calls “the third element.” I argue that this third element functions as a formal provocation for counter- modalities that change the story of sexual assault, creating a portal to resistance and healing.
Teaching English in Early Childhood Education: a Description of the Pedagogical Practice Adopted in the Municipality of Southern Brazil
Authors: Bortolotti Fernanda Seidel , Krause-Lemke Cibele 
Published: November 2021

The purpose of this study is to investigate teaching English in Early Childhood Education (ECE) in a municipality of southern Brazil. The country has not agreed to make English language teaching compulsory for this age, but some private schools have introduced English language teaching on the premises .
Regarding methodology, the experimental study was conducted in schools “A” and “B”. Private school “A” was represented by a teacher with her group of four-year-old children. State school “B” was attended by two representatives of the volunteer program who worked with a group of five-year-olds. The research tools were observation in the classroom from each group, questionnaires answered by the teacher and volunteers, individual interviews with each of them, and a documentary analysis of the pedagogical project of schools, pedagogical materials. The experiment was conducted in compliance with all ethical standards.
The analysis resulted in an understanding of the importance of such aspects as: duration and frequency of classes, the number of groups, lack of books for students and teachers, limited use of English by teachers and students; and the predominance of listening/speaking among other students' skills in both schools. The teacher and the volunteers jointly acknowledged this advantage, noting that different techniques were used. Each group of teachers tried to improve the learning process, taking into account the preferences of the students. The volunteers of school “B” followed the structured plan of the lesson according to the program, used various types of activities. In school “A” the teacher used one type of activity at the lesson. Although the group had four-year-old children, it did not have significant negative consequences.
According to the results of the study, it can be concluded that the approach proposed by the teachers is based on teaching English as a foreign language (EFL). The development of language education in Brazil has a long way , given the establishment of public policy on еarly сhildhood еducation system in combination with theoretical and practical researches used in the educational process.
Pengembangan Model Pengukuran Sistem Informasi Akademik Terhadap Kepuasan Pengguna Menggunakan Technology Acceptance Model Dan Delone&Mclean
Authors: . Herlina , Lestari Ninik Sri 
Published: November 2021

Peran teknologi sebagai penunjang kebutuhan administrasi kependidikan salah satunya adalah Sistem Informasi Akademik (SIAK) yang di rancang untuk mempermudah para pengguna khususnya mahasiswa dalam melakukan kegiatan akademik.Tujuan dari penelitian ini adalah menguji pengaruh perilaku pengguna Sistem Informasi Akademik Berbasis Web terhadap kepuasan pengguna sistem informasi. Model penelitian yang digunakan mengacu pada model penerimaan dan kepuasan terhadap penerapan teknologi sistem informasi yakni Technology Acceptance Model (TAM) dan model Delone McLean. Data dikumpulkan dari kuesioner yang dibagikan kepada 400 mahasiswaÂ Institut Seni Budaya Indonesia (ISBI) Bandung. Analisis data menggunakan software AMOS (Analysis of Moment Structure) dan analisis regresi melalui program SPSS. Hasil penelitan menunjukkan bahwa pengguna sistem informasi akademik berbasis Web memiliki pengaruh positif dan signifikan terhadap kepuasan pengguna sistem informasi pada Institut Seni Budaya Indonesia (ISBI) Bandung. Analisis koefisien determinasi (0,474) menunjukkan bahwa sebesar 47,4% dari total tingkat kepuasan pengguna sistem informasi dipengaruhi oleh variabel perilaku. Hal ini menunjukkan semakin baik penggunaan sistem informasi akademik berbasis web yang diterapkan, maka tingkat kepuasan pengguna sistem informasi akademik tersebut semakin tinggi
Penentuan Algoritma Similarity Yang Akurat Pada Sistem Berbasis Cased Based Reasoning Untuk Identifikasi Ikan
Authors: . Suhadi , Atika Prima Dina , Lestari Panca Indah , Ramadian Afzil 
Published: November 2021

Abstrak - Indonesia sebagai negara kepulauan memiliki potensi perikanan yang sangat besar dan beragam, Indonesia memiliki 17.508 pulau dengan garis pantai sepanjang 81.000 km dan 70% (5,8 juta km2) dari luas Indonesia adalah lautan, adapun keragaman sumberdaya laut untuk beragam jenis ikan merupakan ciri tersendiri untuk mengenali dan memahami suatu spesies secara detail. Identifikasi jenis ikan yang bersifat computing masih terbatas, dalam penelitian analisa yang digunakan adalah sistem Case Based Reasoning (CBR). CBR merupakan penalaran berbasis kasus yang mempunyai metode penyelesaian masalah berbasis pengetahuan untuk mempelajari dan memecahkan masalah berdasarkan pengalaman masa lalu. CBR adalah suatu model komputasi untuk meniru penalaran manusia untuk memberikan kemudahan dalam mencari kasus berdasarkan kemiripan, kemudian case based reasoner mencari kasus-kasus yang ada pada basis kasus untuk menemukan kasus yang memiliki kemiripan dengan persoalan yang sedang dihadapi (retrieve). Oleh karena itu, proses CBR sering juga disebut dengan istilah â€œ4 Reâ€ yaitu Retrive, Retain, Revise, Reuse. Dalam paradigma pemecahan masalah sebuah permasalahan baru diselesaikan dengan cara membandingkan dengan kasus-kasus pada dimasa lampau dan menggunakannya kembali kasus-kasus yang ada untuk menyelesaikan suatu masalah sekarang. Tujuan dari penelitian ini adalah untuk melakukan evaluasi dan komparasi Algoritma Weighted Euclidean Distance (WED), Algoritma Hamming and Levenshtein Distances (HLD), Algoritma Cosine Coefficient for Text-Based Cases (CCFTBC) dan Algoritma k-Nearest Neighbor (k-NN) untuk identifikasi jenis ikan. Hasil penelitian ini adalah untuk mencari pemilihan hasil komparasi algoritma pada sistem CBR yang cepat dan akurat.Â Copyright Â© 2019 LPPM - STMIK IKMI CirebonThis is an open access article under the CC-BY licenseÂ
Meningkatkan Kemampuan Menulis dan Self-Efficacy Mahasiswa Pada Mata Kuliah Intermediate Writing Dengan Metode Self-Assessment
Authors: Annisah Annisah , Samsudin Samsudin , Waliyudin Waliyudin 
Published: November 2021

Penelitian ini bertujuan untuk meningkatkan kemampuan menulis dan self-afficacy mahasiswa dengan menggunakan metode penilaian self-assessment. Penelitian ini akan diterapkan pada mata kuliah Intermediate Writing. Metode yang digunakan adalah pre-eksperimen dengan desain one pretest dan posttest. Sampel yang digunakan pada penelitian ini adalah mahasiswa semester II Program Studi pendidikan Bahasa Inggris STKIP Taman Siswa Bima yang berjumlah satu kelas. Tahap penelitian dilakukan dalam 3 tahap yang mencakup; Tahap I: melakukan observasi dan wawancara, penyusunan instrument, penyusunan materi ajar, validasi instrument, uji coba instrument, menganalisis hasil uji coba instrument untuk mengetahui validitas dan reliabilitasnya. Tahap II: melakukan pretest, treatment, observasi, dan posttest. Tahap III: mengolah data hasil pretest, posttest, dan instrument lainnya, membandingkan hasil sebelum dan sesudah pemberian treatment, memberikan saran dan kesimpulan. Hasil yang diperoleh pada penelitian adalah terjadi peningkatan kemampuan menulis dan self-efficacy mahasiswa pada mata kuliah Intermediate Writing. hasil pre-test menunjukkan nilai minimum yang diperoleh mahasiswa adalah 43 dan nilai maksimum adalah 65, sedangkan pada post test terjadi peningkatan yang cukup baik yaitu nilai minimum yang diperoleh mahasiswa adalah 75 dan nilai maksimum adalah 90.
Penerapan Aplikasi Google Classroom Dalam Matakuliah Matematika Diskrit Pada Masa Pandemi Covid-19
Authors: Juliangkary Eliska , Pujilestari Pujilestari 
Published: November 2021

Pada penelitian ini bertujuan mendeskripsikan belajar mahasiswa menggunakan Aplikasi Google Classroom dalam matakuliah Matematika Diskrit pada masa pandemic covid-19. Penelitian ini dilaksanakan mulai semester ganjil tahun akademik 2020/2021 pada Mahasiswa semester V matakuliah Matematika Diskrit sebanyak 34 orang, Program Studi Pendidikan Matematika. FSTT UNDIKMA Mataram. Instrumen yang digunakan dalam penelitian ini adalah berupa angket/kuisioner dengan menggunakan google form. Wawancara dilakukan pada saat akhir kegiatan belajar mengajar secara daring. Analisis data dilakukan dengan menggunakan excel untuk menghitung jumlah persentase serta nilai rata-rata. Indikator angket diberikan pada mahasiswa terdiri dari ; 1) Respon siswa mudah dalam mengakses Aplikasi Google Classroom, 2) keefektifan dalam pembelajaran Matematika Diskrit dalam menggunakan Aplikasi Google Classroom, 3) pemahaman terhadap materi dalam pembelajaran dengan menggunakan Aplikasi Google Classroom, (4) mudah pemahaman materi Matematika Diskrit jika menggunakan aplikasi Aplikasi Google Classroom selama masa Pandemi Covid 19. (5) motivasi mahasiswa dalam melakukan belajar online karena menggunakan Aplikasi Google Classroom,(6) kualiatas interaksi guru dan siswa dalam Pembelajaran menggunakan Aplikasi Google Classroom. Berdasarkan indikator penerapan Aplikasi Google Classroom menunjukan rata-rata mahasiswa menjawab setuju sebesar 75.5% dan tidak setuju sebesar 25.5%. Hasil tersebut menunjukan bahwa penerapan Google Classroom mendapatkan tanggapan yang baik dari mahasiswa, sehingga dapat digunakan untuk pembelajaran pada matakuliah Matematika Diskrit.
PERAN PENGAWASAN DALAM OPERASIONAL KOPERASI KONSUMEN YAYASAN PUSAKA RAUDHATUL IRFAN DESA KUTAWARGI KEC. RAWAMERTA KAB. KARAWANG
Authors: Sungkono  
Published: November 2021

Perkembangan koperasi di Indonesia dapat dikatakan timbul teggelam, pada saatnya maju namu kadang menjadi mengalami kemunduran karena lemahnya Pengawan. Pada kondisi ini, penting untuk memberikan edukasi kepada segenap unsur yang menangani koperasi tersebut. Pengabdi merasa perlu utnuk memberikan masukankepada Pengurus khusunya kepada Pengawas Koerasi yaitu tentang Peran Pengawasan dalam Operasional Koperasi Konsumen Yayasan Pusaka Raudhatul Irfan Desa Kutawargi Kec. Rawamerta Kab. Karawang
Kergiatan pengabdian kepada masyarakat secara daring (online) selama satu hari ( 7 jam
) dapat disimpulkan bahwa : (a). Secara umum para pihak yang berkepentingan pada Koperasi Konsumen Yayasan Pusaka Raudhatul Irfan Desa Kutawargi Kecamatan Rawamerta Kabupaten Karawang menyadari masih kurangnya sistem pengawasan; (b). Peran kepengawasan pada Koperasi Konsumen Yayasan Pusaka Raudhatul Irfan Desa Kutawargi Kecamatan Rawamerta Kabupaten Karawang belum berjalan secara optimal; (c). Tingkat kepercayaan terhadap fungsi kepengawasan yang dilakukan masih rendah, oleh karena itu semua setuju untuk dilakukan sistem aplikasi

Kata kunci : Pengawas, Amanah, Maju.
PENYULUHAN DALAM MENINGKATKAN USAHA MIKRO, KECIL DAN MENENGAH (UMKM) MASYARAKAT DESA PAMEKARAN KECAMATAN BANYUSARI KARAWANG
Authors: Sinta Maria Dewi  , Lilis Astutiawaty  
Published: November 2021

Covid-19 memiliki dampak yang besar untuk masyarakat menengah ke bawah, karena perekonomian menurun dan juga banyak pengurangan hak kerja (phk) bagi para pegawai di perusahaan/pabrik. Banyak pedagang kaki lima yang tidak bisa berjualan dengan normal karena adaanya wabah virus corona dan kekurangan mata pencaharian, dan jasa ojek online pun tidak bisa beroperasi seperti biasa karena adanya aturan PSBB dan beberapa orderan jasa yang menurun karena adanya social distancing. Pemerintah sudah berusaha maksimal dalam membantu masyarakat yang kekurangan dengan memberikan bantuan sosial berupa sembako dan bantuan lainnya. Pemerintah pun telah memberikan kelonggaran untuk membayar kredit, pajak dan keringanan tagihan listrik. Masyarakat dan pemerintah perlu bekerja sama dalam memerangi covid-19, agar perekonomian indonesia dapat membaik.Kata Kunci : Covid-19 , PSBB , Social Distancing
Covid-19 had a great impact for the lower middle society, as the economy declined and also much reduction in employment rights (phk) for employees in companies/factory. Many street vendors cannot sell normally due to the presence of corona virus outbreaks and lack of livelihoods, then even online ojek services cannot operate as usual due to the presence of PSBB rules and declining service order due to the presence of social distancing. The government is already trying to utmost in helping the deprived public by providing social aid in the form of a sembako, etc. Then the government also provided credit-paying leeway, taxes were also borne by the government, and the leniency of electricity bills. The public and government need to cooperate in combating covid-19, in order for the economy of indonesia to improve.Keywords : Covid-19 , PSBB , Social Distancing
ABOUT STYLES AND METAMORPHOSES (the Issue of Definitions in the Study of Sarmatian Animal Style)
Authors: Korolkova E. F. 
Published: November 2021

This paper is devoted to the problems of scientific definitions concerning the study of the Sarmatian animal style art. This art is represented with the gold decorative objects which often ornamented with colour inlays of different shapes, mostly made of turquoise often used together with other minerals. This art shows the specific features to distinct it from the phenomenon of the Scythian animal style. Decoration of the artistic wares with colour inlays reflects a specific aesthetic tastes and typical method of jewelry of the Sarmatian era. This polychromic effect used to be considered as a very essential feature of the Sarmatian era.
But there were some different heterogeneous cultures which show artistic traditions of different origin in the area inhabited by Sarmatian tribes in the turn of Christian era. Polychromic styles were of different character and type. So, the so called polychromic style is a very conventional definition which comprises some different variants.
One of the groups of objects belonging to Sarmatian culture is characterized with very abundant decoration of turquoise inlays. This visual feature inspired Mark Schukin to launch a new term «turquoise-golden style» which was taken up by archaeologists and became a professional definition. But even scholars mean different comprehension in this term. So, now it is clear that this term is too indeterminate and it is not able to describe the certain artistic style and artistic culture. There were a lot of golden objects in heterogeneous cultures and in different times which were decorated with inlays made of turquoise. They show different styles and the only feature could not determine the artistic style. Any style could be determined with a complex of essential features.
The definition «turquoise-golden style» nothing means and should be forgotten to avoid confusion and mess in scientific studies.