bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enzyme Free Electrochemiluminescence Sensor of Histamine Based on Graphite‐carbon Nitride Nanosheets
Authors: Mesgari Fazeleh , Salehnia Foad , Beigi Sepideh Mohammad , Hosseini Morteza , Ganjali Mohammad Reza 
Published: July 2021

AbstractThe determination of histamine as one of the most important seafood poisoning compounds is essential nowadays. This paper reports a simple novel ECL sensor with g−C3N4 nanosheets (NSs) as an effective signal probe for the measurement of histamine without using any enzymatic reactions or complicated modifications. The ECL response of the sensor was linearly proportional to the concentration of histamine ranging from 1.0×10−7 to 7.5×10−4 mol/L, with a detection limit of 4.30×10−8 mol/L (R2=0.98401). The relative standard deviation (RSD) in repeatability and reproducibility tests were calculated to be 4.7 % and 3.6 % respectively. The presented sensor was successfully applied to the determination of histamine in canned tuna fish samples where it gave recoveries that ranged from 99.72 % to 101.96 % indicating that the method presented here is sensitive with high precision and is expected to have significant potential applications in clinical and the freshness quality of seafood.
Experimental and model validation of a phase change material heat exchanger integrated into a real building
Authors: Triscari Gabriele , Santovito Michele , Bressan Maurizio , Papurello Davide 
Published: July 2021

SummaryLatent heat thermal energy storages (LHTES) are a promising technology with a wide range of applications in the framework of energy efficiency improvement. Phase change materials provide a big storage capacity, but their thermal conductivities are always extremely low. The use of finned tube heat exchangers is nowadays the best solution to enhance PCMs thermal performances. This allows significant charging and discharging rates. The major challenge concerns the balance between thermal performances and high material costs. A proper design of the heat transfer surfaces is essential to limit the system overall cost. Two different heat exchangers solutions, with radial and longitudinal fins are here examined. The design of the LHTES is performed by deploying a simplified FEM numerical model specifically developed for the application. A validation procedure based on laboratory tests with a small LHTES prototype was also carried out. The obtained results confirmed the reliability of the numerical model and justify its adoption as a tool for the design phase. The FEM model allows to effectively simulate the system thermal behaviour and assess the impact of the different HEX geometrical parameters on thermal performances. Based on this information it was possible to perform the optimization of the heat transfer surfaces and to derive the best heat exchanger layout in terms of material usage. The results showed that the solution with longitudinal fins is the most efficient, with 215 kg of steel less required for the realization of the finned heat exchanger.
Profiles and interrelationships of functional soil microbiomes involved in phosphorus cycling in diversified agricultural land‐use systems
Authors: Li Minghui , Hu Junli , Lin Xiangui 
Published: July 2021

AbstractSoil microbiomes play important roles in both transformation and utilization of phosphorus (P) in agroecosystems. By targeting at 18S rRNA, pqqC, and phoD genes, respectively, the community compositions of soil arbuscular mycorrhizal (AM) fungi and inorganic P‐solubilizing and organic P‐mineralizing prokaryotes were investigated across fields with annual crops or vegetables and orchards with peach trees or tea bushes in a common Agri‐technology Park, representing four typical agricultural land‐use types in Eastern China. Both annual crop and vegetable fields exhibited higher soil fertility and phosphatase activity, while both peach tree and tea bush orchards contained greater abundances of AM fungal and pqqC genes. Land‐use type also significantly affected the community compositions of soil AM fungi, and pqqC‐ and phoD‐harboring prokaryotes, with soil available P as the common driver for all functional groups above. Three main ecological clusters (modules) with distinctive interactive features, that is, synergistic, competitive, and inactive were observed in the co‐occurrence network comprised of the three groups involved in P‐cycling. The modules exhibited various distributions among the four land‐use types, and the correlations with soil pH, available P and K, and N:P were shown. Altogether, the results demonstrated the changes in gene abundances, diversity indices, community compositions, and interrelationships of functional groups involved in P‐cycling in response to distinct land‐use types, and highlighting the synergistic potential among groups to alleviate P deficiency.
Review on heterogeneous catalysts for the synthesis of perfumery chemicals via isomerization, acetalization and hydrogenation
Authors: Hartati  , Firda Putri Bintang Dea , Bahruji Hasliza , Bakar Mohd Bakri 
Published: July 2021

AbstractSynthetic fragrance has dominated the perfumery industry in recent decades due to the ability to produce perfumery ingredients on a large scale at a low cost. Extensive research in the field of synthetic perfumery chemical involved the utilization of catalysts to improve the productivity. This review will discuss recent advances of heterogeneous catalysts for the synthesis of perfumery chemicals as fragrance ingredients. Transition from homogeneous to heterogeneous catalysts will be included in order to provide insight into the benefits of heterogeneous catalysts to overcome the limitation of homogeneous reaction. Isomerization, acetalization and hydrogenation were identified as three main reactions for the synthesis of perfumery chemicals based on the number of reported work since 2000. This review will focus on α‐pinene and α‐pinene oxide as the main molecular substrates, however, different molecules, for example, linalool, citronellal and cinnamaldehyde will also be included. The synthesis, modification and possible mechanisms for the reactions involving zeolite, aluminosilicate, metal oxides, metal organic framework, monometallic and bimetallic nanoparticles as heterogeneous catalysts will be discussed. Discussion on isomerization and acetalization reactions will focus on the acidity and the porosity of the catalysts as the two main factors that determine the conversion and selectivity. For perfumery chemicals produced via hydrogenation reaction, the role of monometallic and bimetallic nanoparticles catalysts will be discussed in the chemoselective reduction of cinnamaldehyde and citronellal.
Dimethylarginine dimethylaminohydrolase 1 as a novel regulator of oligodendrocyte differentiation in the central nervous system remyelination
Authors: Uyeda Akiko , Quan Lili , Kato Yuki , Muramatsu Nagaaki , Tanabe Shogo , Sakai Kazuhisa , Ichinohe Noritaka , Kawahara Yukio , Suzuki Tatsunori , Muramatsu Rieko 
Published: July 2021

AbstractRemyelination is a regenerative process that restores the lost neurological function and partially depends on oligodendrocyte differentiation. Differentiation of oligodendrocytes spontaneously occurs after demyelination, depending on the cell intrinsic mechanisms. By combining a loss‐of‐function genomic screen with a web‐resource‐based candidate gene identification approach, we identified that dimethylarginine dimethylaminohydrolase 1 (DDAH1) is a novel regulator of oligodendrocyte differentiation. Silencing DDAH1 in oligodendrocytes prevented the expression of myelin basic protein in mouse oligodendrocyte culture with the change in expression of genes annotated with oligodendrocyte development. DDAH1 inhibition attenuated spontaneous remyelination in a cuprizone‐induced demyelinated mouse model. Conversely, increased DDAH1 expression enhanced remyelination capacity in experimental autoimmune encephalomyelitis. These results provide a novel therapeutic option for demyelinating diseases by modulating DDAH1 activity.
Simple, but effective: Nasal splinting for airway securement in free flap reconstruction following orbital exenteration
Authors: Rauchenwald Tina , Dejaco Daniel , Henninger Benjamin , Morandi Evi M. , Pülzl Petra , Pierer Gerhard , Riechelmann Herbert , Wolfram Dolores 
Published: July 2021

AbstractOrbital exenteration is a disfiguring procedure that often results in free tissue transfer for reconstructive purposes. The reconstructive focus is the obliteration of dead space while sparing the nasal airway, particularly if the medial orbital wall was resected. Prolapse of transferred tissue into the nasal airway may cause breathing difficulties drastically compromising quality of life. The objective of this study was to demonstrate the effectiveness and feasibility of temporary nasal septum splints as mechanical support for transferred tissue, to prevent airway obstruction. This novel application technique was employed in three patients between 2017 and 2018. No flap loss or sino‐orbital fistulas were observed. On postoperative MRI and endoscopy, a patent nasal airway was observed at all times. Temporary nasal splinting in combination with free tissue transfer proved to be a simple, but effective reconstructive option for securing the nasal airway following orbital exenteration with resection of the medial orbital wall.
Tissue‐Specific Regulation of Ferroportin in Wild‐Type and Hjv‐/‐ Mice Following Dietary Iron Manipulations
Authors: Katsarou Angeliki , Gkouvatsos Konstantinos , Fillebeen Carine , Pantopoulos Kostas 
Published: July 2021

Hepcidin is a liver‐derived peptide hormone that limits iron egress from tissues to the bloodstream. It operates by binding to the iron exporter ferroportin, which blocks iron transport and tags ferroportin for degradation. Genetic hepcidin inactivation leads to hereditary hemochromatosis, a disease of iron overload. We used wild‐type and Hjv‐/‐ mice, a model of hemochromatosis, to examine the expression of ferroportin and other proteins of iron metabolism in hepcidin target tissues. The animals were previously subjected to dietary iron manipulations. In Hjv‐/‐ mice, hepcidin messenger RNA correlated significantly with hepatic iron load (r = 0.8211, P < 0.001), but was substantially lower compared with wild‐type controls. Duodenal ferroportin and divalent metal transporter 1 (DMT1), as well as splenic and hepatic ferroportin, were overexpressed in these animals. A high‐iron diet (2% carbonyl iron) suppressed duodenal DMT1 levels in both wild‐type and Hjv‐/‐ mice; however, it did not affect duodenal ferroportin expression in Hjv‐/‐ mice, and only reduced it in wild‐type mice. In contrast, the high‐iron diet decreased splenic ferroportin exclusively in Hjv‐/‐ mice, whereas it induced hepatic ferroportin exclusively in wild‐type mice. Conclusion: Our data show that dietary iron differentially affects ferroportin expression in mouse tissues and are consistent with hepcidin‐dependent and hepcidin‐independent mechanisms for ferroportin regulation. In the Hjv‐/‐ mouse model of hemochromatosis, duodenal ferroportin remains unresponsive to iron but DMT1 is appropriately iron‐regulated.
Ethnic, socio‐economic and geographic inequities in maternal health service coverage in Australia
Authors: Fox Haylee , Topp Stephanie M. , Lindsay Daniel , Callander Emily 
Published: July 2021

AbstractBackgroundDisparities in health service use exist in many sectors of Australia's health system, particularly affecting the most vulnerable people in the population, who are typically those with the greatest healthcare needs. Understanding patterns of health service coverage is critical for acknowledging the underlying, systemic drivers including racialised practices that inhibit the uptake of health services for certain population groups. This study aims to determine whether there are disparities in health service utilisation between socioeconomic, geographic and ethnic groups of mothers who experience hypertension, diabetes and mental health conditions.MethodsThis study utilised a linked administrative healthcare dataset containing data of all mothers who gave birth in Queensland, Australia, between 2012 and 2015 (n = 186,789), plus their resultant babies (n = 189,909). The study compared health service utilisation for mothers with maternal health conditions between population groups.ResultsThe results of this study showed a broad trend of inequitable health service utilisation, with mothers who experienced the greatest healthcare needs—First Nations, rural and remote and socio‐economically disadvantaged mothers—being less likely to access health services and in some cases when care was accessed, fewer services being utilised during the perinatal period.ConclusionAccess to health care during the perinatal period is a reflection of Australia's general health system strengths and weaknesses, in particular a failure of the government to translate national and state policy intent into acceptable and accessible care in rural and remote areas, for First Nations women and for mothers experiencing socio‐economic disadvantage.
Exploring the pandemic's potential effects on workers' collectivist values, prosocial behaviors, and attitudes toward mistreatment
Authors: Li Ning , Liao Huiyao , Pan Jingzhou , Harris T. Brad 
Published: July 2021

AbstractThe global COVID‐19 pandemic has fundamentally changed the way we live and work in the short‐term, but history suggests that the crisis may also exert deeper, longer‐lasting effects. With the aim of providing preliminary insight into this possibility, we theoretically construct and empirically test hypotheses for how exposure to COVID‐19 stimuli (e.g., reading or watching media coverage, observing relief efforts) relates to the deep‐seated values that guide workers' attitudes and behaviors. Specifically, we build from prior work to posit that exposure to COVID‐19 stimuli is positively associated with workers' self‐transcendent prosocial values, which motivate prosocial behaviors directed toward society as a whole (i.e., charitable donations) and coworkers (i.e., helping). Extend the extant literature, we further argue that exposure to COVID‐19 stimuli will be positively associated with conservation values emphasizing self‐restraint, submission, protection of order, and harmony in relations, which in turn influences workers' willingness to tolerate mistreatment by authorities (i.e., abusive supervision, authoritarian leadership, exploitation). Evidence from 2,929 full‐time Chinese employees tracked for nearly 2 months and a diverse sample of 310 workers in the United States generally support our arguments, but also provide insight into potential cultural nuances.
Occupational insecticide exposure and risk of non‐Hodgkin lymphoma: A pooled case‐control study from the InterLymph Consortium
Authors: De Roos Anneclaire J. , Schinasi Leah H. , Miligi Lucia , Cerhan James R. , Bhatti Parveen , ‘t Mannetje Andrea , Baris Dalsu , Benavente Yolanda , Benke Geza , Clavel Jacqueline , Casabonne Delphine , Fritschi Lin , Hofmann Jonathan N. , Huynh Tran , Monnereau Alain , Piro Sara , Slager Susan L. , Vajdic Claire M. , Wang Sophia S. , Zhang Yawei , Bernstein Leslie , Cocco Pierluigi 
Published: July 2021

AbstractEvidence for the human health effects of pesticides is needed to inform risk assessment. We studied the relationship between occupational insecticide use and risk of non‐Hodgkin lymphoma (NHL) by pooling data from nine case‐control studies participating in the InterLymph Consortium, including 7909 cases and 8644 controls from North America, the European Union and Australia. Insecticide use was coded using self‐report or expert assessment, for insecticide groups (eg, organophosphates, pyrethroids) and active ingredients (eg, malathion, permethrin). Associations with insecticides were estimated using logistic regression to produce odds ratios (ORs) and 95% confidence intervals (CI) for all NHL and NHL subtypes, with adjustment for study site, demographic factors and use of other pesticides. Occupational insecticide use, overall, was not associated with risk of NHL. Use of organophosphate insecticides was associated with increased risk of all NHL and the subtype follicular lymphoma, and an association was found with diazinon, in particular (ever use: OR = 2.05, 95%CI: 1.24‐3.37). The carbamate insecticide, carbaryl, was associated with risk of all NHL, and the strongest associations were found with T‐cell NHL for ever‐use (OR = 2.44, 95%CI: 1.13‐5.28) and longer duration (>8 years vs never: OR = 2.90, 95%CI: 1.02‐8.25). There was no association of NHL with other broad groups of insecticides, including organochlorines and pyrethroids, and some inverse associations were estimated in relation to historical DDT use. Our findings contribute to the totality of evidence available to help inform risk decisions by public health and regulatory agencies of importance given continued, widespread use of organophosphate and carbamate insecticides.
Can pelvic floor muscle training prevent perineal laceration? A systematic review and meta‐analysis
Authors: Gomes Lopes Lia , Maia Dutra Balsells Marianne , Teixeira Moreira Vasconcelos Camila , Leite de Araújo Thelma , Teixeira Lima Francisca Elisângela , de Souza Aquino Priscila 
Published: July 2021

AbstractBackgroundPelvic floor muscle training (PFMT) is reportedly able to reduce risk factors for perineal trauma. However, the effects of these exercises on perineal injuries are unclear.ObjectiveTo investigate the effectiveness of PFMT in the prevention of perineal laceration.Search strategySearches were conducted in PubMed/Medline, LILACS, Scopus, Cochrane Library, Web of Science, and CINAHL. For search strategies, we combined the terms PFMT, tear, laceration, perineum, and delivery.Selection criteriaWe included randomized controlled trials that evaluated the effectiveness of PFMT for the prevention of perineal laceration during vaginal delivery. There were no period or language limitations.Data collection and analysisWe conducted data extraction and synthesis. We performed a quality appraisal, a qualitative synthesis, and for meta‐analysis we used the Software R.Main resultsNine studies were included. In most studies, PFMT was performed daily, with a wide range of the number of contractions and sustainability. Prevalence of perineal laceration had a wide range and information on laceration degree was limited. Meta‐analysis showed that PFMT was not effective to prevent perineal laceration.ConclusionPelvic floor muscle training does not prevent perineal laceration. Further studies are needed to investigate different protocols and interventions.
The perceptions of female genital self‐image and its associations with female sexual distress
Authors: Benabe Erika , Fuentes Yesenia , Roldan Gabriela , Ramos Mariluz , Pastrana Manuel , Romaguera Josefina 
Published: July 2021

AbstractObjectiveTo evaluate the perception of women living in Puerto Rico regarding their genitalia and explore the associations of those perceptions with female sexual distress.MethodsWomen from Puerto Rico willing to complete a self‐administered online survey from June 2018 through July 2020 were included in this cross‐sectional study. Inclusion criteria included being between 21 and 65 years of age, living in Puerto Rico, having identified as heterosexual, bisexual, or lesbian, and having been sexually active. Descriptive statistics were calculated. The Mann–Whitney test, Pearson's correlation, and robust linear regression were used to associate female genital self‐image and sexual distress.ResultsThe most common negative thought and perception within women was dissatisfaction with the size of their genitalia (21.9%), and 21.3% of women contemplated undergoing cosmetic surgery, mainly to increase and improve sensation. For each 1‐unit increase in the Female Genital Self‐Image Scale score, the Female Sexual Distress Scale‐Revised score decreased by 1.24 units (95% confidence interval –1.67 to –0.82).ConclusionA better genital self‐image perception might lower levels of sexual distress. Screening instruments could help to identify poor genital perception and sexual distress.
Enlargement of the genital hiatus is associated with prolapse recurrence in patients undergoing sacrospinous ligament fixation
Authors: Garcia Alexandra N. , Ulker Ashley , Aserlind Alexandra , Timmons Douglas , Medina Carlos A. 
Published: July 2021

AbstractObjectiveTo correlate genital hiatus (GH) size with surgical failures in patients undergoing sacrospinous ligament fixation (SSLF) and compare anatomic outcomes after classification based on GH size.MethodsA retrospective review of 81 patients who underwent SSLF for apical prolapse from 2010 to 2016 at a teaching hospital. Anatomical outcome is reported using the Pelvic Organ Prolapse Quantifications System. A comparison of parametric continuous variables was performed using unpaired Student t test. Categorical variables were evaluated using Pearson's χ2 test and Fisher's exact test. A P value <0.05 was considered significant.ResultsAmong the 81 patients, no difference in age, parity, body mass index, preoperative prolapse stage or follow‐up time was noted between those whose surgery succeeded and those with failed surgery. Postoperatively, a widened GH was significantly associated with recurrent prolapse (P < 0.001). When the preoperative size of the GH was dichotomized into widened (≥4 cm) or normal (<4 cm), there was a non‐significant (P = 0.444) trend of more failures in the widened GH group. A posterior colporrhaphy did not improve success.ConclusionBoth preoperative and postoperative widened GH correlated with having more surgical failures following SSLF. Importantly, postoperatively a normal size GH was significantly associated with more surgical success.
Management of work stress in science education lecturers' population using rational emotive occupational health coaching: Implication for educational evaluators
Authors: Ugwuanyi Christian S. , Okeke Chinedu I. O. , Ekwueme Uchechukwu H. 
Published: July 2021

AbstractIntroductionNigerian university lecturers face a lot of works in the day‐to‐day discharge of their responsibilities as academics. This constitutes a lot of stress for them as documented in the literature. However, literature is scarce on how these lecturers manage their work stress. Thus, the researchers explored the efficacy of rational emotive occupational health coaching (REOHC) on the management of work stress among lecturers.MethodA randomised controlled trial group experimental research design was adopted using a sample size of 84 lecturers in Science Education Departments of the sampled universities. An occupational stress index was used in the gathering of necessary data for the study. The REOHC treatment lasted for 12 weeks after which the participants were posttested and a follow‐up measure followed after 3 months of the termination of the treatment. Repeated measures analysis of variance statistical approach was used to analyse the obtained data.ResultsIt was revealed that REOHC was significantly (p < 0.05) effective in the management of work stress in a population of science education lecturers in Nigeria.ConclusionREOHC enables science education lecturers to effectively manage their work stress to maximise their work outputs. This finding implicates the expertise of Educational Evaluators.