bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endophytic fungi associated with soybean plants and their antagonistic activity against Rhizoctonia solani
Authors: Sallam Nashwa , Ali Esmat F. , Seleim Mohamed A. A. , Khalil Bagy Hadeel M. M. 
Published: March 2021

Abstract
Background
Fungal endophytes produce many secondary metabolites that can reduce root rot diseases. Soybean is a particularly important crop worldwide. Endophytic fungi can be isolated, identified, and incorporated into sustainable agriculture for the biological control of many diseases.

Results
The aim of this study was to isolate some endophytic fungi for controlling the most important diseases of soybean plants and to study the mechanisms underlying this biocontrol regarding the suppression of pathogens. Ten endophytic fungi were isolated from soybean plants. Among them, the 3 fungi isolates that exhibited a high percentage of antagonistic activity against Rhizoctonia solani, the causal pathogen of root rot disease of soybean plants, were identified as Trichoderma longibrachiatum S12, T. asperellum S11, and T. atroviride PHYTAT7. The 3 fungi isolates had the ability to produce pectinase and chitinase and to solubilize phosphors. Moreover, they produced siderophores and indole acetic acid (IAA), which have a strong effect on the growth of the plants. The 3 isolates reduced disease severity by 64, 60, and 55%, respectively than the infected control.

Conclusion
The results suggest that certain endophytic fungi associated with soybean plants have potential for the management of root rot diseases in soybean. Moreover, these isolates can be considered as having a growth-promoting effect in soybean plants.
Compilation of the resuscitation guidelines for COVID-19 patients in resource-constrained developing nations
Authors: Jain Kompal , Chauhan Rajeev , Bloria Summit , Sarna Rashi 
Published: March 2021

Abstract
Background
The world is presently struggling with the pandemic of COVID-19 (coronavirus disease). Owing to the poor outcome and high contagiousness of COVID-19, cardiopulmonary resuscitation (CPR) of COVID-19-positive patients is still questionable.

Main body
It is imperative for the healthcare workers to follow the precautions during CPR of suspected or confirmed COVID-19 patients. In the present article, we have compiled the resuscitation guidelines subjected to the availability of resources in India/developing nations.

Conclusion
Compression-only CPR should be initiated whether cardiac arrest is of presumed hypoxic or cardiac etiology. If a patient with an unknown status/suspected/confirmed COVID-19 has out of the hospital cardiac arrest, hands-only CPR could be performed only after covering the mouth and nose of the patient and healthcare worker with the face mask or cloth. During in-hospital cardiac arrest, patients should be shifted to a negative pressure ventilation room, and healthcare worker should wear personal protective equipments.
Probiotics role of Saccharomyces cerevisiae and Bacillus subtilis in improving the health status of rabbits’ gastrointestinal tract
Authors: Helal Farouk , El-Badawi Alaa , El-Naggar Soad , Shourrap Mohamed , Aboelazab Osama , Abu Hafsa Salma 
Published: March 2021

Abstract
Background
Probiotics are direct-fed microbial feed supplements which can modulate the gut microflora by competing intestinal pathogens through a competitive process. The present study was conducted to investigate the effect of feeding Saccharomyces cerevisiae, Bacillus subtilis or their mixture on blood biochemical constituents, intestinal pathogenic load and intestinal histological changes of growing New Zealand White (NZW) rabbits.

Results
Serum total protein, albumin, and globulin were (P ≤ 0.05) increased for rabbits fed supplemented diets. Microbial pathogenic load of small intestinal and caecal contents (E. coli and C. perfringens) showed reduction (P ≤ 0.05) for rabbits fed supplemented diets, while, lactobacillus spp. recorded higher counts (P ≤ 0.05) in intestinal and caecal contents of rabbits fed probiotics supplemented diets than control group. Small intestine length, villus height and crypt depth were higher (P ≤ 0.05) with probiotic diets than control. Musculosa depth was depressed (P ≤ 0.05) with probiotic diets.

Conclusions
It could be concluded that the addition of Bacillus subtilis or Saccharomyces cerevisiae to diets of growing NZW rabbits by 0.1% is recommended to minimize the pathogenic intestinal load and increasing of beneficial lactobacillus strains as well as improving the intestinal barriers integrity.
Chromosomal abnormalities predisposing to infertility, testing, and management: a narrative review
Authors: Yahaya Tajudeen O. , Oladele Esther O. , Anyebe Daniel , Obi Chidiebere , Bunza M. D. A. , Sulaiman Ridwan , Liman Usman U. 
Published: March 2021

Abstract
Background
Much interest has not been placed on the role of chromosomal abnormalities in the pathogenesis and rising prevalence of infertility in recent times. This review was conducted to renew public interest on the chromosomal basis of infertility, testing, and management.

Main text
Meiotic and post-zygotic mitotic errors may cause infertility-predisposing chromosomal abnormalities, including Klinefelter syndrome, Jacob syndrome, Triple X syndrome, Turner syndrome, and Down syndrome. Chromosomal abnormalities such as deletion, translocation, duplication, inversion, and ring chromosome may also predispose to infertility. Notable features of male chromosomal infertility include spermatogenic failure, characterized by azoospermia, oligospermia, and gonadal dysgenesis, while females include premature ovarian insufficiency, amenorrhea, spontaneous abortion, and gonadal dysgenesis. The risk of these abnormalities is influenced by maternal age and environmental factors such as chemical exposure, smoking, and alcohol consumption. Most chromosomal abnormalities occur spontaneously and are not treatable. However, early prenatal screening and diagnostic tests can lessen the effects of the conditions. There is also a growing belief that certain diets and drugs capable of changing gene expressions can be formulated to neutralize the effects of chromosomal abnormalities.

Conclusion
Meiotic and mitotic errors during gametogenesis and fetal development, respectively, can cause chromosomal abnormalities, which predispose to infertility. Couples who are at increased risk, particularly those with a family history of infertility and women at an advanced age (≥ 35 years), should seek medical advice before getting pregnant.
Fertilization influence on biomass yield and nutrient uptake of sweet corn in potentially hardsetting soil under no tillage
Authors: Canatoy Ronley C. , Daquiado Nonilona P. 
Published: March 2021

Abstract
Background
Hardsetting soils are considered problem soils due to its behavior of becoming hard and unbearable to cultivate not until rewetted. Few investigations were conducted in this kind of problem soil; hence, information about biomass yield and nutrient uptake is still elusive. This study investigated the impact of potentially hardsetting soil on the biomass yield and nutrient uptake of sweet corn under no-tillage cultivation system with varying fertilization treatments.

Results
The application of full NPK + 1 Mg ha−1 VC increased stover and grain yield by 26–106% and 11–135%, respectively. Approximately 64% and 112% of sweet corn stover and grain yield increased when treated with full NPK. Highly significant quadratic relationship (P < 0.001) was revealed between total biomass yield and nutrient uptake of sweet corn, implying that 98–99% of the variation in total biomass could be elucidated by its nutrient uptake. Further, this indicated the suitability of nutrient uptake function that could be used as an estimate in the progression of total biomass accumulation. The application of full NPK showed statistically significant (P < 0.001) nitrogen and phosphorus use efficiency across treatments. The soil in the experimental area was a potentially hardsetting soil due to its rapid soil strength development at least 4 days from wetting. This implies that with continued use, proper soil management must be implemented like reduced tillage and organic matter application to facilitate structure formation and binding of soil particles by labile fraction in organic matter.

Conclusion
Application of organic amendment in combination with inorganic fertilizer could be a sustainable production strategy on sweet corn production system in potentially hardsetting soil under no tillage through enhanced nutrient uptake and biomass accumulation.
Recent developments in photoacoustic imaging and sensing for nondestructive testing and evaluation
Authors: Chen Sung-Liang , Tian Chao 
Published: March 2021

AbstractPhotoacoustic (PA) imaging has been widely used in biomedical research and preclinical studies during the past two decades. It has also been explored for nondestructive testing and evaluation (NDT/E) and for industrial applications. This paper describes the basic principles of PA technology for NDT/E and its applications in recent years. PA technology for NDT/E includes the use of a modulated continuous-wave laser and a pulsed laser for PA wave excitation, PA-generated ultrasonic waves, and all-optical PA wave excitation and detection. PA technology for NDT/E has demonstrated broad applications, including the imaging of railway cracks and defects, the imaging of Li metal batteries, the measurements of the porosity and Young’s modulus, the detection of defects and damage in silicon wafers, and a visualization of underdrawings in paintings.
Shoreline evolution and modern beach sand composition along a coastal stretch of the Tyrrhenian Sea, southern Italy
Authors: Morrone Consuele , Ietto Fabio 
Published: March 2021

AbstractThis contribution focuses on a multidisciplinary research showing the geomorphological evolution and the beach sand composition of the Tyrrhenian shoreline between Capo Suvero promontory and Gizzeria Lido village (Calabria, southern Italy). The aim of the geomorphological analysis was to reconstruct the evolutionary shoreline stages and the present-day sedimentary dynamics along approximately 6 km of coastline. The results show a general trend of beach nourishment during the period 1870–2019. In this period, the maximum shoreline accretion value was estimated equal to + 900 m with an average rate of + 6.5 m/yr. Moreover, although the general evolutionary trend is characterized by a remarkable accretion, the geomorphological analysis highlighted continuous modifications of the beaches including erosion processes. The continuous beach modifications occurred mainly between 1953 and 1983 and were caused mainly by human activity in the coastal areas and inside the hydrographic basins. The beach sand composition allowed an assessment of the mainland petrological sedimentary province and its dispersal pattern of the present coastal dynamics. Petrographic analysis of beach sands identified a lithic metamorphi-clastic petrofacies, characterized by abundant fine-grained schists and phyllites sourced from the crystalline terrains of the Coastal Range front and carried by the Savuto River. The sand is also composed of a mineral assemblage comparable to that of the Amato River provenance. In terms of framework detrital constituents of QFL (quartz:feldspars:aphanitic lithic fragments) and of essential extraclasts, such as granitoid:sedimentary:metamorphic phaneritic rock fragments (Rg:Rs:Rm), sand maturity changes moderately from backshore to shoreface, suggesting that transport processes had a little effect on sand maturity. Moreover, the modal composition suggests that the Capo Suvero promontory does not obstruct longshore sand transport from the north. Indeed, sands displaced by currents driven by storm-wave activity bypass this rocky headland.
Performance of horizontal flow constructed wetland for secondary treatment of domestic wastewater in a remote tribal area of Central India
Authors: Shukla Reetika , Gupta Deepak , Singh Gurudatta , Mishra Virendra Kumar 
Published: March 2021

AbstractThe purification of the primary treated domestic sewage was performed in the present study through the horizontal sub-surface flow constructed wetland (CW) of 10 × 3.5 m dimension. The study was performed using three setups of CW 1 (Unplanted CW), CW 2 (CW planted with macrophyte Typha latifolia), and CW 3 (CW planted with two species of macrophyte T. latifolia and Commelina benghalensis). The purification experiments were performed by converting one type of CW into the other form sequentially, i.e., CW 1 was built first and after the experiments, it was converted into CW 2 and then CW 3. The CW was filled with a layer of coarse and fine gravel of 70 cm depth as filter media in 1:2 ratio. Each set of wetland was operated for 3 months (12 wk) during which the treatment performance of wetlands for basic physicochemical parameters was evaluated. The CW was operated in continuous mode at an average hydraulic loading rate of 250 L h− 1 and the treated effluent was analysed twice every week at four different sampling points having hydraulic retention times (HRT) of 12, 24, 36 and 48 h for important sewage quality parameters All the three setups of CW were able to clean the primary treated sewage significantly. Among the three sets of wetlands used, CW 3 was the best performer removing 79, 77, 79, 79, and 78% of biochemical oxygen demand, chemical oxygen demand, nitrate, ammonia, and phosphate respectively in 48 h HRT. Among the three sets of wetlands, the CW 3 removed the highest percent of total coliforms, fecal coliforms, and E. coli as 64, 61 and 52% respectively.
Evaluation of a multidisciplinary lipid clinic to improve the care of individuals with severe lipid conditions: a RE-AIM framework analysis
Authors: Jones Laney K. , McMinn Megan , Kann David , Lesko Michael , Sturm Amy C. , Walters Nicole , Chen Nan , Fry Kerrianne , Brownson Ross C. , Gidding Samuel S. , Williams Marc S. , Rahm Alanna Kulchak 
Published: March 2021

AbstractBackgroundIndividuals with complex dyslipidemia, or those with medication intolerance, are often difficult to manage in primary care. They require the additional attention, expertise, and adherence counseling that occurs in multidisciplinary lipid clinics (MDLCs). We conducted a program evaluation of the first year of a newly implemented MDLC utilizing the RE-AIM (reach, effectiveness, adoption, implementation, and maintenance) framework to provide empirical data not only on program effectiveness, but also on components important to local sustainability and future generalizability.MethodsThe purpose of the MDLC is to increase the uptake of guideline-based care for lipid conditions. Established in 2019, the MDLC provides care via a centralized clinic location within the healthcare system. Primary care providers and cardiologists were invited to refer individuals with lipid conditions. Using a pre/post-study design, we evaluated the implementation outcomes from the MDLC using the RE-AIM framework.ResultsIn 2019, 420 referrals were made to the MDLC (reach). Referrals were made by 19% (148) of the 796 active cardiology and primary care providers, with an average of 35 patient referrals per month in 2019 (SD 12) (adoption). The MDLC saw 83 patients in 2019 (reach). Additionally, 50% (41/82) had at least one follow-up MDLC visit, and 12% (10/82) had two or more follow-up visits in 2019 (implementation). In patients seen by the MDLC, we found an improved diagnosis of specific lipid conditions (FH (familial hypercholesterolemia), hypertriglyceridemia, and dyslipidemia), increased prescribing of evidence-based therapies, high rates of medication prior authorization approvals, and significant reductions in lipid levels by lipid condition subgroup (effectiveness). Over time, the operations team decided to transition from in-person follow-up to telehealth appointments to increase capacity and sustain the clinic (maintenance).ConclusionsDespite limited reach and adoption of the MDLC, we found a large intervention effect that included improved diagnosis, increased prescribing of guideline-recommended treatments, and clinically significant reduction of lipid levels. Attention to factors including solutions to decrease the large burden of unseen referrals, discussion of the appropriate number and duration of visits, and sustainability of the clinic model could aid in enhancing the success of the MDLC and improving outcomes for more patients throughout the system.
Risk factors for mortality in hospitalized patients with COVID-19 from three hospitals in Peru: a retrospective cohort study
Authors: Díaz-Vélez Cristian , Urrunaga-Pastor Diego , Romero-Cerdán Anthony , Peña-Sánchez Eric Ricardo , Fernández Mogollon Jorge Luis , Cossio Chafloque Julio Darwin , Marreros Ascoy Gaston Cristobal , Benites-Zapata Vicente A. 
Published: March 2021

Background: Peru was one of the countries with the highest COVID-19 mortality worldwide during the first stage of the pandemic. It is then relevant to evaluate the risk factors for mortality in patients hospitalized for COVID-19 in three hospitals in Peru in 2020, from March to May, 2020. Methods: We carried out a retrospective cohort study. The population consisted of patients from three Peruvian hospitals hospitalized for a diagnosis of COVID-19 during the March-May 2020 period. Independent sociodemographic variables, medical history, symptoms, vital functions, laboratory parameters and medical treatment were evaluated. In-hospital mortality was assessed as the outcome. We performed Cox regression models (crude and adjusted) to evaluate risk factors for in-hospital mortality. Hazard ratios (HR) with their respective 95% confidence intervals (95% CI) were calculated. Results: We analyzed 493 hospitalized adults; 72.8% (n=359) were male and the mean age was 63.3 ± 14.4 years. COVID-19 symptoms appeared on average 7.9 ± 4.0 days before admission to the hospital, and the mean oxygen saturation on admission was 82.6 ± 13.8. While 67.6% (n=333) required intensive care unit admission, only 3.3% (n=16) were admitted to this unit, and 60.2% (n=297) of the sample died. In the adjusted regression analysis, it was found that being 60 years old or older (HR=1.57; 95% CI: 1.14-2.15), having two or more comorbidities (HR=1.53; 95% CI: 1.10-2.14), oxygen saturation between 85-80% (HR=2.52; 95% CI: 1.58-4.02), less than 80% (HR=4.59; 95% CI: 3.01-7.00), and being in the middle (HR=1.65; 95% CI: 1.15-2.39) and higher tertile (HR=2.18; 95% CI: 1.51-3.15) of the neutrophil-to-lymphocyte ratio, increased the risk of mortality. Conclusions: The risk factors found agree with what has been described in the literature and allow the identification of vulnerable groups in whom monitoring and early identification of symptoms should be prioritized in order to reduce mortality.
Clinically isolated bacteria resistance to silver-based wound dressings
Authors: Norton Rhy , Finley Phillip J 
Published: March 2021

Objective:Silver has become a global treatment option with the US Food and Drug Administration providing marketing clearance for many silver-impregnated wound dressings and topical agents. However, the increased use of silver-based products across medical disciplines has raised questions concerning the development of acute silver resistance. In this study, the efficacy of previously identified silver-resistant clinical bacteria (Klebsiella pneumoniae and Enterobacter cloacae) against a variety of commercially available silver-based wound dressings was further investigated.Method:To further explore the clinical significance of these isolates, multiple time-course and repeat-challenge assays were conducted with nine dressings using a panel of silver-resistant and silver-sensitive microorganisms. Silver-impregnated dressings were ranked by silver species, quantity of silver and overall efficacy.Results:Both silver-resistant strains were largely unaffected and exhibited phenotypic resistance even when exposed to the high silver concentrations found in commercially available wound dressings. In stark contrast, the majority of the dressings were able to maintain a high degree of efficacy over the course of 72 hours and during repeated bacterial challenges against silver-sensitive microorganisms.Conclusion:Our findings provide additional evidence that clinically significant silver-resistance has emerged in the clinical setting. Such resistant microbes are capable of sustained silver resistance against a wide variety of silver adjuvants. These findings suggest that the further development and dissemination of these resistance mechanisms could significantly impact current practices in wound healing.
Flexible resource provisioning of polarization independent coherent PONs based on non-orthogonal multiple access and multiCAP modulation
Authors: Izquierdo David , Altabas Jose A. , Barrio Miguel , Clemente Jesus , Millan Pablo , Sarmiento Samael , Lazaro Jose A. , Rommel Simon , Puerta Rafael , Vegas-Olmos Juan J. , Tafur Monroy Idelfonso , Garces Ignacio 
Published: March 2021

A combined non-orthogonal multiple access (NOMA) and multiband carrierless amplitude and phase modulation (multiCAP) scheme is proposed for flexible resource provisioning in coherent passive optical networks (PONs). While the proposed combination increases the data-rate and the number of users through the inclusion of NOMA and multiCAP, the coherent reception increases the range and splitting factor of the network through optical power budget enhancement. The proposed system is experimentally evaluated providing a 20 Gb/s aggregated data-rate per wavelength with 10G optoelectronics and applied in two main PON scenarios with four spectral configurations from full-band CAP to four-band multiCAP. The first PON scenario consists of an existing PON that the network operator requires to increase the number of users; NOMA with full-band CAP or multiCAP can be introduced replacing one or more users of the existing PON by one or several new sub-networks and multiplexing the sub-networks by NOMA. In the other PON scenario, several PONs can be nested sharing an initial splitter and achieving a larger number of users by the combination of NOMA and multiCAP. The proposed techniques are fully compatible with other multiplexing techniques such as dense wavelength division multiplexing, which should be considered to achieve higher numbers of users.