bluuebunny/crossref_metadata_2025_split huggingface dataset:
Penerapan Tindakan Kompres Hangat Dalam Menurunkan Skala Nyeri Pada Penderita Gout Arthritis
Authors: Muna Naila , Natalya Wiwiek 
Published: December 2021

AbstractGouty Arthritis is a disease associated with an inborn errors of purine matabolism. Gout Arthritis occurs due to a buildup of uric acid that exceeds the normal limit in the joints. This can cause pain in gouty arthritis sufferers so giving warm compresses is necessary for gouty arthritis sufferers. This study was a descriptive case study aiming to describe the application of warm compresses in reducing pain scale in patirnts with Gouty Arthritis. A client assessment form, observation sheets, pain scales, WWZ (Warm Water Zak), and uric acid measurement kid were the instuments being used to collect data. The findings showed that there was a decrease in the pain scale in patiens with Gouty Arthritis. In case I, there was a decrease of pain scale from 5 to 2; meanwhile, in case II the pain scale decreased from 6 to 3. The conclusion from this study was that the application of warm compress therapy with WWZ (Warm Water Zak) could reduce the pain scale. Thus, patients of Gouty Arthritis are suggested to apply warm compress therapy with WWZ (Warm Water Zak) to reduce the pain because of the disease.Keywords: Warm compress, pain, gouty arthritis
AbstrakGout Arthritis merupakan hasil metabolisme atau pecahan purin dari makanan yang tinggi purin. Gout Arthritis terjadi karena penumpukan asam urat yang melebihi batas normal dipersendian. Hal ini dapat menyebabkan nyeri pada penderita gout arthritis sehingga pemberian kompres hangat sangat diperlukan untuk penderita gout arthritis. Studi kasus ini bertujuan untuk menggambarkan penerapan tindakan kompres hangat dalam menurunkan skala nyeri pada penderita Gout Arthtitis. Metode studi kasus ini menggunakan studi kasus deskriptif. Instrumen studi kasus ini dengan menggunakan format pengkajian klien, lembar observasi, skala nyeri, WWZ (Warm Water Zak) dan alat ukur untuk mengukur kadar asam urat. Hasil studi kasus ini menunjukkan ada penurunan skala nyeri pada penderita Gout Arthritis pada kasus I terjadi penurunan skala nyeri awal 5 turun menjadi 2 sedangkan pada kasus II skala nyeri awal 6 turun menjadi 3. Simpulan dari studi kasus ini bahwa terapi kompres hangat dengan WWZ (Warm Water Zak) dapat menurunkan skala nyeri. Saran bagi klien yang mengalami Gout Arthritis agar dapat mengontrol dengan menggunakan terapi kompres hangat menggunakan WWZ (Warm Water Zak) secara mandiri.Kata kunci: Kompres hangat, nyeri, gout arthritis
El estilo neocolonial en Mendoza, Argentina en la primera mitad del siglo XX
Authors: Cremaschi Verónica 
Published: December 2021

El siguiente artículo profundiza en la arquitectura neocolonial de influencia hispánica en la provincia de Mendoza, tendencia que surgió y se popularizó en la primera mitad del siglo XX en el marco de búsquedas culturales relacionadas con la identidad.
Para este estudio analizamos distintas obras de arquitectura y las ponemos en relación con las opiniones y representaciones publicadas en la prensa del período en los que la temática hispánica está presente.
Como resultado observamos, durante las primeras décadas del siglo xx, un notable interés por lo español, que se expresó a partir de distintos soportes materiales y que constituye un importante acervo patrimonial de la ciudad y la cultura poco destacado por la historiografía local.
Psychological determinants of the attitude towards vascular interventions in patients with lower limb ischaemia
Authors: Stanišić Michał-Goran , Rzepa Teresa , Szmatuła Natalia 
Published: December 2021

BackgroundCritical lower limb ischaemia is associated with a 20% annual risk of amputation and death. It is necessary to activate pa-tients’ personal resources which comprise mental dispositions needed to effectively cope with the disease. The objective of the study was to evaluate the correlation between the attitude toward the vascular reconstruction and self-efficacy (SE), health locus of control (HLoC) and own life quality (QOL) assessment in patients with critical lower limb ischaemia.Participants and procedureThe study involved 64 patients with critical lower limb ischaemia (Rutherford 4 and 5), 26 women and 38 men. Four scales were applied during primary admission: the Generalized Self-Efficacy Scale; the Satisfaction with Life Scale; the Multidimensional Health Locus of Control Scale; and the visual scale revealing attitude to vascular reconstruction.ResultsThe attitude to the vascular reconstruction was positive (M = 8.50). The lowest grades were given by those hospitalised several times during follow-up (M = 8.30); women expressed low grades (M = 7.71). An overall positive correlation was found between the positive attitude to the surgery and self-efficacy (p = .012), internal HLoC (p = .041) and external locus (p = .026). In the patients who died within six months from baseline assessment, no correlations were found. In subjects with no readmission, a correlation was found between positive attitude to surgery and the external personal HLoC (p = .023). In patients with subsequent readmissions, a correlation was found between the originally positive attitude to the surgery and poor self-efficacy (p = .009).ConclusionsPatients with weak mental dispositions cannot cope with difficult situations and show a tendency to experience strong emotions, concentrating on their deficiencies, resulting in decreased motivation and feeble engagement in treatment. Poor mental disposition influences the final outcome of the vascular reconstruction.
O discurso em notícias falsas sobre universidades brasileiras: uma perspectiva semiolinguística
Authors: Goulart Blank Julia Caroline , Boaventura Luis Henrique , Freitas Ernani Cesar de 
Published: December 2021

Este estudo objetiva analisar a ação das notícias falsas na construção de uma mise-en-scène que resulte um discurso de demérito para as universidades brasileiras. A metodologia utilizada é exploratória, bibliográfica e qualitativa. Na análise dos dados empregamos a Teoria Semiolinguística proposta por Charaudeau (2016). O corpusde estudo é composto por duas notícias falsas publicadas no Facebook. Constatamos que o sujeito comunicador encena em seu discurso um imaginário que associa a nudez às universidades de forma pejorativa, buscando um sujeito interpretante associado ao seu espectro político-ideológico, que veja essas cenas com asco e adira a seu contrato de comunicação.
Thực trạng tuân thủ điều trị của bệnh nhân tăng huyết áp đang điều trị ngoại trú tại Bệnh viện Trường Đại học Tây Nguyên năm 2020
Authors: Trang Phan Thị Huyền , Quyên Nguyễn Thị Kim , Tuyến Nguyễn Mạnh , Hương Vũ Thị Thanh 
Published: December 2021

Nghiên cứu nhằm mô tả thực trạng tuân thủ điều trị của bệnh nhân ngoại trú đang điều trị bệnh tăng huyết áp. Đây là nghiên cứu mô tả cắt ngang trên 405 bệnh nhân tuổi từ 25 tuổi trở lên đang điều trị ngoại trú tại khoa Khám -Bệnh viện Trường Đại học Tây Nguyên năm 2020. Số liệu được thu thập thông qua việc phỏng vấn trực tiếp dựa trên bộ câu hỏi đã soạn sẵn. Kết quả cho thấy tỷ lệ bệnh nhân tuân thủ điều trị tăng huyết áp là 16%. Trong đó, tỷ lệ bệnh nhân tuân thủ chế độ dùng thuốc liên tục, lâu dài đạt 68,4%. Tỷ lệ bệnh nhân tuân thủ chế độ ăn hạn chế muối, ăn nhiều rau xanh hoa quả tươi và hạn chế sử dụng rượu bia chất kích tích đạt đều trên 50%. Có 57,3% bệnh nhân tuân thủ điều trị về chế độ luyện tập thể dục thể thao. Như vậy, tỉ lệ bệnh nhân tuân thủ điều trị tăng huyết áp ở mức thấp. Do đó việc tư vấn đầy đủ về tầm quan trọng của việc tuân thủ điều trị tăng huyết áp cho bệnh nhân là rất cần thiết, nhằm nâng cao chất lượng điều trị bệnh.
Thực trạng tiếng ồn và giảm thính lực nghề nghiệp tại 3 nhà máy thuộc Công ty thủy điện Ialy tỉnh Gia Lai, năm 2020
Authors: Châu Trần Tô , Vân Ngô Thị Hải , Hoa Phạm Thị Thúy , Hoa Võ Thị , Chiến Viên Chinh , Thủy Trần Thị Thu 
Published: December 2021

Nghiên cứu được thực hiện tại 03 nhà máy Thủy điện (NMTĐ) thuộc Công ty thủy điện IaLy, tỉnh Gia Lai từ tháng 5/2020 đến tháng 4/2021, với phương pháp mô tả cắt ngang trên đối tượng là môi trường lao động và người lao động (NLĐ) trực tiếp sản xuất tại NMTĐ, nhằm mô tả thực trạng tiếng ồn và giảm thính lực nghề nghiệp (GTL NN) sơ bộ của người lao động tại các vị trí làm việc trực tiếp. Số liệu thu thập bằng cách đo tiếng ồn tại 39 vị trí có người lao động thuộc 03 NMTĐ và đo thính lực cho 69 người lao động thường xuyên làm việc và tiếp xúc với tiếng ồn tại 03 NMTĐ. Kết quả cho thấy, cường độ tiếng ồn chung tại thời điểm nghiên cứu là 78,63 ± 15,2dBA, dao động từ 46,9 – 105,7dBA, tỷ lệ mẫu tiếng ồn chung vượt quy chuẩn cho phép là 35,9%. Tỷ lệ NLĐ bị GTL NN 31,4%. Từ đó chúng tôi đưa ra khuyến nghị tăng cường truyền thông, giáo dục về phòng chống bệnh điếc nghề nghiệp cho người lao động.
Đặc điểm dịch tễ học lâm sàng và cận lâm sàng của bệnh nhiễm trùng hô hấp dưới do Respiratory Syncytial Virus ở trẻ từ 2 tháng tuổi đến 15 tuổi tại bệnh viện Xanh Pôn
Authors: Hòa Phạm Văn , Hòa Võ Thị Mỹ 
Published: December 2021

Nghiên cứu của chúng tôi nhằm mục tiêu mô tả đặc điểm dịch tễ học lâm sàng và cận lâm sàng của bệnh nhiễm trùng hô hấp dưới do Respiratory Syncytial Virus (RSV) ở trẻ từ 2 tháng tuổi đến 15 tuổi tại Bệnh viện Xanh Pôn. Qua thăm khám bệnh nhân và hồi cứu bệnh án, theo dõi kết quả điều trị ở 201 trẻ từ 2 tháng tuổi đến 15 tuổi, được chẩn đoán viêm đường hô hấp dưới theo tiêu chuẩn của WHO 2013 vào điều trị tại Bệnh viện Xanh Pôn từ tháng 01/06/2018 đến tháng 31/05/2019. Kết quả cho thấy tuổi trung bình của trẻ mắc là 6,48 ± 2,46 (tháng), thời điểm thường mắc bệnh vào mùa đông 40,4%. Lâm sàng 96,8% bệnh nhân có ho, 95,5% khò khè, 15,8% sốt và 92,1% nghe có ran ở phổi. Trên X-quang có tổn thương phổi lan tỏa (77,5%), nồng độ CRP không tăng (1,04 m/L), số lượng bạch cầu bình thường (10,34 ± 3,49 G/L). Thời gian nằm viện trung bình 7,63 ± 3,27 ngày.
Evaluation of homeopathic and biotherapic treatments in a swine farm to control Escherichia coli infection: a long term study
Authors: Coelho CidÃƒÆ’Ã‚Â©li de Paula , Soto Francisco Rafael , Vuaden Erlete Rosalina , Melville Priscilla Anne , Moreno Andrea Micke , Bonamin Leoni Villano , Benites Nilson Roberti 
Published: December 2021

Background: Escherichia coli is the most important etiological agent in neonatal diarrhea in swine, and Enterotoxigenic Escherichia coli (ETEC) is the most commonly isolated. Regarding to virulence factors, five main types of fimbriae were already described in swine samples: F4 (K88), F5 (K99), F6 (987P), F18 and F41. Thermolabile (LT) and thermostable enterotoxins (ST), as well as shiga-like toxin or verotoxin (Stx2) are also found in isolates of swine origin, related to diarrhoea process.
Methods: This long term study has been developed in a swine farm (Mato Grosso, Brazil), in which 93 piglets were studied and 184 fecal samples were evaluated in two steps, with the aim to search the presence of Escherichia coli and to prepare a specific biotherapic medicine. Each step had one year of interval each other. Concurrently, for each step, a detailed anamnesis was made for choosing the ideal homeopathic medication for each step (Phosphorus 30 CH and Pulsatilla 30 CH, respectively). In each step, four groups consisting of 11-12 piglets and the respective primiparous mother pig were formed, and the treatments happened simultaneously: control group (antimicrobial treatment, the same used in the swine farm), homeopathic medication, E. coli biotherapic and homeopathic medication associated to biotherapic. The medications were made according to the Brazilian Homeopathic Pharmacopeia and the treatment lasted 12 days. After 24 days, in the weaning, the weight gain of each bath was also evaluated. Considering both steps, the research of virulence factors and enterotoxins was carried out in 99 Escherichia coli colonies through Polymerase Chain Reaction - PCR.
Results: In both steps, the homeopathy treated groups passed from 75.0% of diarrhea incidence to 8.3% at the end of the treatment (p
Oral, topical, and inhalation of Calcarea carbonica derivative complex (M8) to treat inflammatory mammary carcinoma in dogs
Authors: Da Silva Daniella Matos , Da Lozzo Eneida Janiscki , Buchi Dorly de Freitas , De Oliveira Carolina , GuÃƒÆ’Ã‚Â©rios Simone Domit 
Published: December 2021

Background: Inflammatory mammary carcinoma (IMC) is locally aggressive, fast growing, highly malignant tumor that affects humans and dogs. Affected dogs usually are presented with generalized edema, pain, erythema, and skin ulceration in mammary glands. Surgery is not recommended and an effective treatment has not been established [1]. Calcarea carbonica derivative complex (M8) has demonstrated anticancer properties in a murine model, by improving innate immune response against tumor cells [2]. M8 is a complex high diluted medication comprised of Calcarea carbonica 16x, Aconitum napellus 20x, Arsenicum album 18x, Asa foetida 20x, Conium maculatum 17x, Ipecacuanha 13x, Phosphorus 20x, Rhus toxicodendron 17x, Silicea 20x, Sulphur 24x, and Thuya occidentalis 19x, dilution procedures have followed standard methodology described at the Brazilian Homeopathic Pharmacopoeia.
Aims: To describe different routes of M8 administration associated with oral pyroxican (non-steroidal anti-inflammatory drug) to treat dogs with IMC.
Methodology: Three female dogs with 10 years old median age were presented to the Veterinary Teaching Hospital at Federal University of Parana, Curitiba (HV-UFPR) with cytological and clinical diagnosis of IMC. Patients were treated with oral (0.5 mL,q12h), topical (q12h) and inhalatory (2 mL, q24h, through an ultrasonic inhalation device) M8, and oral pyroxican (0.3mg/kg, q24h).Thoracic radiographs showed pulmonary metastasis in all dogs.
Results: 7 days after initiating treatment all patients had clinical improvement. It was observed reduction on mammary glands inflammation and decreased pain sensitivity. One patient had 8 month of complete remission. The other two patients died 1 and 2 month after initial treatment. However none of the patients had pulmonary progressive disease, showed by radiographic examinations. Owners revealed treatment satisfaction in regards to quality of life improvement, easy M8 administration, good M8 palatability for dogs, and inflammation reduction.
Conclusion: The present report suggests that M8 influenced positively the anti -inflammatory treatment.
Keywords: Calcarea carbonica complex; inflammatory mammary carcinoma; routes of administration
References
[1] Sorenmo K. Canine mammary gland tumors. Veterinary Clinics of North America: Small Animal Practice. 2003 33(3):573-96.
[2] Oliveira CC, Abud APR, Oliveira SM, GuimarÃƒÆ’Ã‚Â£es FSF, Andrade LF, Di Bernardi RP, Coletto ELO, Kuczera D, Da Lozzo EJ, GonÃƒÆ’Ã‚Â§alves JP, Trindade ES, Buchi DF. Developments on drug discovery and on new therapeutics: highly diluted tinctures act as biological response modifiers. BMC Complementary and Alternative Medicine 2011, 11(101): 2-11.
Evaluation of immune response of BALB/c to homeopathic solutions
Authors: Siqueira Camila , Bonamin Leoni , Motta Priscila , Cardoso Thayná , Coelho Cideli , Couceiro JosÃƒÆ’Ã‚Â© Nelson , Holandino Carla 
Published: December 2021

Introduction: Biotherapics are medicines prepared from etiologic agents, following Brazilian Homeopathic Pharmacopeia. Influenza is a disease that affects thousands of people worldwide every year, motivating the development of new therapies.
Aim: In this study, we developed two biotherapics from live/active influenza A virus, at 12x and 30x, and verified some immune response parameters in mice.
Methodology: The biotherapic was administered to male SPF 4 weeks old Balb/c mice. The protocol was approved by the UFRJ Ethics Committee of Animal Use (Protocol DFBCICB 040). Animals were stimulated daily, blindly, with different homeopathic medicines, at 1% (V/V) for a maximum period of 42 days. Three homeopathic medicines were tested: biotherapic 30x containing active influenza A virus; biotherapic 12x containing active influenza A virus; and thymulin 5cH. The experimental groups were: Group A (5 animals) ÃƒÂ¢Ã¢â€šÂ¬Ã¢â‚¬Å“ administration of thymulin 5cH, Group B (5 animals) ÃƒÂ¢Ã¢â€šÂ¬Ã¢â‚¬Å“ administration of biotherapic 30x, Group C (5 animals) ÃƒÂ¢Ã¢â€šÂ¬Ã¢â‚¬Å“ administration of biotherapic 12x, Group D (5 animals) - administration of a water 30x, Group E (5 animals) - administration of a water 12x, Group F (5 animals) - control (without treatment). After 21 days of treatment, all animals were challenged subcutaneously with the viral hemagglutinin antigen at the concentration of 7 ÃƒÂ¯Ã‚ÂÃ‚Â­g/200ÃƒÂ¯Ã‚ÂÃ‚Â­L and monitored by further 21 days. After euthanasia, all animals were autopsied and the spleen was collected for weight and immunehistochemistry analyses. Additionally, peritoneal washing was done and a ÃƒÂ¢Ã¢â€šÂ¬Ã…â€œpoolÃƒÂ¢Ã¢â€šÂ¬Ã‚Â of samples from each group was prepared to be analyzed by flow citometry.
Results: Mice treated with biotherapic 30x and thymulin 5cH showed similar profile, different from controls, in which a switch of lymphocytes/phagocytes proportion in the peritoneum was seen, followed by predominance of B1b cells in relation to conventional B and T cells (X2, p=0.005). Regarding to T cell population, in the contrary to control, CD4+ cells were predominant in relation to CD8+ cells (X2, p=0.0001). The immunehistochemistry revealed increase in the number of activated CD11b+ macrophages in spleen (p
Cellular Alterations Induced by Candida albicans RC Nosodes: an in vitro Study
Authors: Homsani Fortune , Moreno Gleyce , Siqueira Camila , Grechi Juliana , Santos AndrÃƒÆ’Ã‚Â© Luis , Holandino Carla 
Published: December 2021

Introduction: Candidiasis is an opportunist infection, caused by yeast of the genus Candida, which emerges as one of the main causes of systemic infections in hospitalized patients. Candida albicans is the most common causing agent of these infections. According to the Brazilian Homeopathic Pharmacopeia[1], nosodes are medicines compounded from chemically undefined biological products. Living nosodes are prepared using the etiologic agent of an illness in its infective form, were first developed by Brazilian physician Roberto Costa (RC). Roberto CostaÃƒÂ¢Ã¢â€šÂ¬Ã¢â€žÂ¢s research indicated that living nosodes present a higher capability to stimulate the hostÃƒÂ¢Ã¢â€šÂ¬Ã¢â€žÂ¢s immunological system [2].
Aim: This study aims to evaluate cellular alterations induced in C. albicans yeasts and RAW 264-7 macrophages by Candida albicans RC.
Methodology: To prepare Candida albicans RC, one part of C. albicans infective yeast suspension (108 cell/ml) was diluted in 9 parts of sterile distilled water and submitted to 100 mechanical succussions. This process was successively repeated to the potencies of 12x and 30x1. Water 30x was prepared by the same technique, as control. The cell viability of C. albicans previously treated with nosodes in both potencies and respective controls was evaluated using the samples at the concentration of 10% (V/V), in a volume of 1ml, distributed in 1-3 days. The viability of the yeast cells was analyzed by MTT (3-(4,5-dimetiltiazol-2-il)-2,5-difeniltetrazolic) (5mg/ml) assay [3] and by Propidium Iodide (PI) incorporation methods. Additionally, using macrophages RAW 264-7 as a cell model, Nitric Oxide (NO) production and cell viability were also evaluated. For this, the following protocol of cell treatment was employed: on each experimental day, RAW 264-7 cells were treated 4 times (4 stimuli) with RC nosode 30x at the concentration of 10% (V/V).
Results: The nosodes (12x and 30x) did not present cytotoxic effects on macrophage cells (n=1), or on C. albicans yeasts (n=2), as detected by MTT and PI methods. Moreover, no statistically significant differences on NO production were detected among the experimental groups (n=6).
Conclusion: Preliminary results of in vitro assays indicate that nosodes (12x and 30x) do not alter mitochondrial activity or cell viability of C. albicans. Similarly, treatment by RC nosodes does not seem to alter NO release and mitochondrial activity of RAW macrophages. New experiments are being performed to confirm these preliminary data.
Experimental induced wound cicatrisation after highly diluted products treatment
Authors: Jeronimo Fernando Fortunato , GonÃƒÆ’Ã‚Â§alves Jenifer Pendiuk , Do Nascimento Katia Fialho , De Oliveira Simone Martins , De Oliveira Carolina Camargo , Farias ÃƒÆ’Ã¢â‚¬Â°dison Luiz Prisco , Buchi Dorly de Freitas 
Published: December 2021

Introduction: Skin is an attractive target to study extracellular matrix, due to abundance in Connective tissue. In cases of injuries the first step is an inflammatory reaction and subsequent the healing that involves several changes in the matrix. These changes are fundamental to inflammatory cells activities allowing healing. Highly diluted products were shown to facilitate inflammatory mediators and to activate immune cells in vivo and in vitro, thus it can be effective to wound healing.
Aims: This study aims to evaluate highly diluted products effects on inflammation and cicatrization process.
Methodology: Three compounds (M8 (Aconitum napellus 20dH, Arsenicum album 18dH, Asa foetida 20dH, Calcarea carbonica 16dH, Conium maculatum 17dH, Ipecacuanha 13dH, Phosphorus 20dH, Rhus toxicodendron 17dH, Silicea 20dH, Sulphur 24dH, Thuja occidentalis 19dH), M1 (Chelidonium majus 20dH, Cinnamon 20dH, Echinaceae purpurea 20dH, Gelsemium sempervirens 20dH plus all M8 compounds) and Curcuma cH30 ÃƒÂ¢Ã¢â€šÂ¬Ã¢â‚¬Å“ simple product), were manipulated as a gel and applied on mice dorsal flank after incision and suture (approximately 1 cm and three points), for 3 consecutive days. After the treatments the scars were evaluated macroscopically, the animals were killed, the skin samples collected, fixed and processed for Hematoxilin-Eosin (HE) and Masson Tricromic (to observe the collagen fibers type I). The slices were analyzed and images collected by a light microscope Olympus BX51 with camera attached Olympus DP72.
Results: It was observed a higher and faster rate of tissue epithelization in the treated groups after three days of gel-product application. This could be observed in lower rates in the control group (no treatment) - Figure 1 and 2). Regeneration and organization of connective tissue were proportional to epithelization the treated groups. We also observed evidences of changes in amount of neutrophils and fibroblasts, resulting in changes in the healing period. Analyses for these confirmations are in progress.