bluuebunny/crossref_metadata_2025_split huggingface dataset:
Solving the time-dependent Schrödinger equation by combining smooth exterior complex scaling and Arnoldi propagator
Authors: Wang Shun , Jiang Wei-Chao 
Published: July 2021

Abstract
We develop a highly efficient scheme for numerically solving the three-dimensional time-dependent Schrödinger equation of the single-active-electron atom in the field of laser pulses by combining smooth exterior complex scaling (SECS) absorbing method and Arnoldi propagation method. Such combination has not been reported in the literature. The proposed scheme is particularly useful in the applications involving long-time wave propagation. The SECS is a wonderful absorber, but its application results in a non-Hermitian Hamiltonian, invalidating propagators utilizing the Hermitian symmetry of the Hamiltonian. We demonstrate that the routine Arnoldi propagator can be modified to treat the non-Hermitian Hamiltonian. The efficiency of the proposed scheme is checked by tracking the time-dependent electron wave packet in the case of both weak extreme ultraviolet (XUV) and strong infrared (IR) laser pulses. Both perfect absorption and stable propagation are observed.
Where do angry birds tweet? Income inequality and online hate in Italy
Authors: Denti Daria , Faggian Alessandra 
Published: July 2021

AbstractDo spatial socioeconomic features influence a digital behaviour like cyberhate? Our contribution provides an answer to this question, showing how high levels of income inequality determine high volumes of hate tweets in Italy. Our findings are robust to potential endogeneity problems of income inequality, as well as to the inclusion of confounding factors and to competing estimation strategies. Additionally, we find that education does not act as a protective factor against cyberhate in unequal places, aligning with existing evidence showing that inequality may trigger intolerance, including among educated people, threatening the perceived stability of social positions. Also, in the Italian case, the perception of economic insecurity fuels cyberhate, alongside the transmission of self-interest values along family generations. The latter finding relates to existing evidence supporting the role of persistent social norms in shaping people’s attitudes.
Development of a Novel Drug Delivery System to Deliver Drugs Directly to the Colonic Mucosa, Resulting in Improved Efficacy and Reduced Systemic Exposure for the Treatment of Ulcerative Colitis
Authors: Huntsman Merodean , Lee Shaoying N , Stylli Jack , Stork Cheryl , Shimizu Jeff , Quintana Nelson , Singh Sharat , Wahl Christopher , Chuang Emil 
Published: July 2021

Abstract
Despite recent drug approvals for the treatment of inflammatory bowel diseases (IBDs), there remains a high unmet need for new technologies that can increase drug efficacy by improving site-specific drug delivery while reducing systemic exposure. These technologies must address challenges with formulation; in particular, drugs that are liquid, peptides, or proteins are difficult to formulate using existing delayed and extended oral release technologies. They also have the potential to improve efficacy and reduce systemic exposure for certain drugs by delivering higher doses directly to the site of inflammation. A novel drug delivery system is being developed for delivery at a prespecified part of the gastrointestinal (GI) tract. This autonomous mechanical capsule uses an algorithm based on reflected light to deliver soluble formulations of drugs to the predefined location. This system has significant advantages over other traditional delayed release oral formulations because it functions independently of human physiological variables such as pH and transit time and can deliver liquid formulations, peptides, and proteins. Such a system can ensure a predictable high luminal drug exposure and limited degradation or systemic absorption in the upper GI tract and would therefore be ideal for treatment of disorders such as IBD and colon cancer.
Chromosome-scale genome assembly of the transformation-amenable common wheat cultivar ‘Fielder’
Authors: Sato Kazuhiro , Abe Fumitaka , Mascher Martin , Haberer Georg , Gundlach Heidrun , Spannagl Manuel , Shirasawa Kenta , Isobe Sachiko 
Published: July 2021

AbstractWe have established a high-quality, chromosome-level genome assembly for the hexaploid common wheat cultivar ‘Fielder’, an American, soft, white, pastry-type wheat released in 1974 and known for its amenability to Agrobacterium tumefaciens-mediated transformation and genome editing. Accurate, long-read sequences were obtained using PacBio circular consensus sequencing with the HiFi approach. Sequence reads from 16 SMRT cells assembled using the hifiasm assembler produced assemblies with N50 greater than 20 Mb. We used the Omni-C chromosome conformation capture technique to order contigs into chromosome-level assemblies, resulting in 21 pseudomolecules with a cumulative size of 14.7 and 0.3 Gb of unanchored contigs. Mapping of published short reads from a transgenic wheat plant with an edited seed-dormancy gene, TaQsd1, identified four positions of transgene insertion into wheat chromosomes. Detection of guide RNA sequences in pseudomolecules provided candidates for off-target mutation induction. These results demonstrate the efficiency of chromosome-scale assembly using PacBio HiFi reads and their application in wheat genome-editing studies.
Disease Prognostic Biomarkers in Inflammatory Bowel Diseases—A Reality Check
Authors: Zilbauer Matthias , Heuschkel Robert 
Published: July 2021

Abstract
Inflammatory bowel diseases [IBD] such as Crohn’s disease [CD] and ulcerative colitis [UC] are complex conditions presenting with a wide range of phenotypes. Given major variation in disease severity and outcomes as well as response to existing therapies, a personalised treatment approach stands the chance of improving the overall disease outcome as well as minimising potentially harmful side effects. However, disease activity or distribution at the point of diagnosis are poor predictors of future disease outcome. Hence, the urgent need to develop biomarkers that could either predict the overall disease course [i.e., disease prognostic biomarkers] or the response to individual therapies [i.e., disease predictive biomarkers]. Despite the widely accepted need for such biomarkers to improve the management of IBD patients, their development has proven to be challenging for a number of reasons. Based on our own experience in this field, we perform a reality check on existing evidence, discuss main challenges, and outline future perspectives.
Nurse triage accuracy in the evaluation of syncope according to European Society of Cardiology guidelines
Authors: Zaboli Arian , Ausserhofer Dietmar , Sibilio Serena , Paulmichl Rupert , Toccolini Elia , Losi Chiara , Giudiceandrea Alberto , Pfeifer Norbert , Brigo Francesco , Turcato Gianni 
Published: July 2021

AbstractAimsThe role of triage for patients admitted to the emergency department (ED) for a syncopal transitory loss of consciousness (TLOC) has not been debated, and no comparisons with the recent European Society of Cardiology (ESC) guidelines are currently available. To verify the ability of triage to correctly prioritize patients with syncopal TLOC.Methods and resultsAll patients who received a triage assessment at the ED of the Merano Hospital (Italy) between 1 January 2017 and 30 June 2019 for a syncope were considered. All syncope were reclassified according to the aetiology reported in the ESC guidelines. The baseline characteristics of the patients were recorded and divided according to the severity code provided during triage into two study groups: high priority (red/orange) and low priority (yellow/green/blue). The outcome of the study was the presence of a diagnosed cardiac cause within 30 days after the admission. A total of 2066 patients were enrolled (14.3% high priority vs. 85.7% low priority). Cardiac syncope was present in 7.5% of patients. Nurse triage showed a sensitivity for cardiac syncope of 44.8%, a specificity of 88.1%, and an accuracy of 84.9%. The observed discriminatory ability presented an area under the receiver operating characteristic curve of 0.685 (95% confidence interval 0.638–0.732). The possible identification of the aetiology of the syncopal TLOC by the nurse showed good agreement with the medical diagnosis (Cohen’s kappa 0.857, P &lt; 0.001).ConclusionsIn cases of syncopal TLOC, nurse triage had a fair specificity but suboptimal sensitivity for cardiac causes. Specific nursing assessments following triage (e.g. precise scores or electrocardiogram) could improve the triage performance.
A Chromosome-Level Genome of the Agile Gracile Mouse Opossum (Gracilinanus agilis)
Authors: Tian Ran , Han Kai , Geng Yuepan , Yang Chen , Guo Han , Shi Chengcheng , Xu Shixia , Yang Guang , Zhou Xuming , Gladyshev Vadim N , Liu Xin , Chopin Lisa K , Fisher Diana O , Baker Andrew M , Leiner Natália O , Fan Guangyi , Seim Inge 
Published: July 2021

Abstract
There are more than 100 species of American didelphid marsupials (opossums and mouse opossums). Limited genomic resources for didelphids exists, with only two publicly available genome assemblies compared with dozens in the case of their Australasian counterparts. This discrepancy impedes evolutionary and ecological research. To address this gap, we assembled a high-quality chromosome-level genome of the agile gracile mouse opossum (Gracilinanus agilis) using a combination of stLFR sequencing, polishing with mate-pair data, and anchoring onto pseudochromosomes using Hi-C. This species employs a rare life-history strategy, semelparity, and all G. agilis males and most females die at the end of their first breeding season after succumbing to stress and exhaustion. The 3.7-Gb chromosome-level assembly, with 92.6% anchored onto pseudochromosomes, has a scaffold N50 of 683.5 Mb and a contig N50 of 56.9 kb. The genome assembly shows high completeness, with a mammalian BUSCO score of 88.1%. Around 49.7% of the genome contains repetitive elements. Gene annotation yielded 24,425 genes, of which 83.9% were functionally annotated. The G. agilis genome is an important resource for future studies of marsupial biology, evolution, and conservation.
Effect of inlet/outlet on thermal performance of naturally ventilated building
Authors: Maher Dhahri , Hana Aouinet , Arjmand Jamal Tabe , Issakhov Alibek , Sammouda Habib , Sheremet Mikhail , Sharma Shubham 
Published: July 2021

Abstract
Ventilation is a way of improving the air quality of rooms by circulation. The position of the inlet and outlet greatly influences the thermal comfort. This attempt proposes to analyse the effect of the position of window openings for a room building with natural ventilation and the air flow and temperature distribution numerically using a commercial computational fluid dynamics (CFD) code. This proposed study consists of (i) approving the numerical model against experimental data gathered in an environment similar to the one used in simulations and (ii) applying the CFD model to explore the results of four varying configurations of ventilator on the natural ventilation system and thermal comfort. For the varying arrangements, the wind speed is 0.2 m⋅s−1 perpendicular to the openings for a wind, (iii) evaluating the comfort level utilizing the Air Diffusion Performance Index (ADPI) on the basis of ASHRAE 55-210 criteria. The obtained results show that the positions of outlet and inlet openings highly affect the performance in the thermal comfort while they have a trivial effect on the occupied zone mean velocity. The computational results showed that the two cases (a) and (b) present results very close to each other with a slight difference at the center of the chamber. Most of the calculated values (effective draft temperature, EDT) are between (−1.7 and 1.1). Then ADPI is over 70% for case (a) and over 75% for case (b), so all points they are located in the comfort zone. The results affirmed also that configuration with inlet openings set at 1.022 m above ground and an outlet opening set at 0.52 m brings about the most applicable solution ventilation efficiency and give the best EDT that fulfills the criteria of ASHRAE 55-210 with an ADPI of ~90%.
The Effects of Gunshot Residue Components (Pb, Ba, and Sb) on the Life History Traits ofLucilia sericata(Diptera: Calliphoridae)
Authors: Kökdener Meltem , Yılmaz Ahmet Fazıl 
Published: July 2021

AbstractThe present study aimed to investigate the impact of gunshot residue (GSR) components (Pb, Sb, and Ba) on the life history parameters of Lucilia sericata (Meigen, 1826) (Diptera: Calliphoridae). This experiment was carried out at the Zoology Department, the Ondokuz Mayıs University in 2020. About 50 larvae, respectively were exposed to the chicken liver with four different concentrations of GSR particles and life history parameters recorded. A two-way analysis of variance (Two way ANOVA) was used on the larval weight, and length, development time, percentage of pupal and larval survival. Pearson’s correlation coefficient was used to assess the association between life-history parameters and the concentration of GSR. The total development times decreased with increasing Sb, Ba, and Pb concentrations in the diets 1–3 d when compared to the control The results showed that Ba and Sb significantly decreased larval and pupal survival and GSR decreased the pupa and adult weight as compared to the control. We concluded that life-history parameters of L. sericata are sensitive to GSR residue and heavy metal changes in the environment. The presence of gunshot residue in the corpse should be kept in mind in a criminal investigation.
Evaluating the Effectiveness of the Italian Interlocking Ban: An Empirical Analysis of the Personal Ties Among The Largest Banking and Insurance Groups in Italy
Authors: Ghezzi Federico , Picciau Chiara 
Published: July 2021

Abstract
In 2011, Italy introduced a ban on interlocking directorates in the financial sector, prohibiting members of the boards of directors and of the internal control bodies, as well as top managers of banking, insurance, and financial companies, from holding any such office in a competing company or group. Empirical studies have demonstrated conflicting results concerning the effectiveness of the Italian anti-interlocking provision. Some studies claim that interlocking directorates have decreased but have not been completely eliminated, which suggests possible persisting limits to competition. Other studies instead show the ban to have a procompetitive effect, at least in the banking sector, which would be at odds with a slight reduction in personal ties. Our article addresses this inconsistency by mapping the interlocking directorates among the 25 largest banking groups and the 25 largest insurance groups operating in Italy before and after the introduction of the ban. We show that although interlocking directorates were widespread at the end of 2010, the interlocking ban reached its goal in the banking and insurance sectors. Anticompetitive effects may, however, still exist, especially considering that the anti-interlocking provision does not affect ownership connections among competing financial companies and groups.
Migration distance is a fundamental axis of the slow-fast continuum of life history in boreal birds
Authors: Winger Benjamin M , Pegan Teresa M 
Published: July 2021

AbstractSeasonal migration is intrinsically connected to the balance of survival and reproduction, but whether migratory behavior influences species’ position on the slow-fast continuum of life history is poorly understood. We found that boreal-breeding birds that migrate long distances exhibit higher annual adult survival and lower annual reproductive investment relative to co-distributed boreal species that migrate shorter distances to winter closer to their breeding grounds. Our study uses “vital rates” data on reproductive output and survivorship compiled from the literature for a species assemblage of 45 species of mostly passerine birds. These species breed sympatrically in North American boreal forests but migrate to a diversity of environments for the northern winter. After controlling for body size and phylogeny, migration distance and apparent annual adult survival are positively related across species. Both migration distance and survival are positively correlated with wintering in environments that are warmer, wetter, and greener. At the same time, longer migrations are associated with reduced time spent on the breeding grounds, lower clutch sizes, and lower fecundity (clutch size × maximum number of broods per year). Although seasonal migration is often associated with high mortality, our results suggest that long-distance migration imposes selection pressures that both confer and demand high adult survival rates. That is, owing to the reproductive cost of long-distance migration, this strategy can only persist if balanced by high adult survival. Our study supports the idea that migration evolves to promote survival of species breeding in seasonal environments. In boreal birds, the evolution of the longest migrations yields the highest survival, but at an inherent cost to annual fecundity. Our results therefore reveal migratory distance as a fundamental axis of the slow-fast continuum that predicts, and is inextricable from, the balance of survival and reproduction.
Comparing minds and machines: implications for financial stability
Authors: Buckmann Marcus , Haldane Andy , Hüser Anne-Caroline 
Published: July 2021

AbstractIs human or artificial intelligence more conducive to a stable financial system? To answer this question, we compare human and artificial intelligence with respect to several facets of their decision-making behaviour. On that basis, we characterize possibilities and challenges in designing partnerships that combine the strengths of both minds and machines. Leveraging on those insights, we explain how the differences in human and artificial intelligence have driven the usage of new techniques in financial markets, regulation, supervision, and policy-making, and discuss their potential impact on financial stability. Finally, we describe how effective mind–machine partnerships might be able to reduce systemic risks.
COVID-19, conspiracies and manufactured consent
Authors: Kahambing Jan Gresil S 
Published: July 2021

Abstract
Questions about what comes next for the coronavirus disease 2019 pandemic have been posed by the editors to everyone except those who proliferate conspiracy theories. Conspiracy theories have consequences for public health. Making these dangers known can initiate discussions on public trust. The problem is that the pressing concerns of the pandemic have enabled manufactured consent to be a suspicious thing known of the propaganda model more than ever. Although such a model can be put into question, the public must also be able to practice empathy and true choice so that asking and responding to the questions at hand considers a responsibility to public health.
Vanishing mediators in public health during COVID-19
Authors: Kahambing Jan Gresil 
Published: July 2021

AbstractPublic health interventions during the coronavirus disease 2019 pandemic aim to ensure that the lessons learned of the crises can prevent historical recurrences. Such interventions can mean vanishing mediators that must cater to a post-pandemic structure. Learning from large-scale political and scientific histories or advances—emancipatory projects, pandemic histories and vaccine developments—as well as individual agencies—physical activity and exercise—at the moment become crucial in rethinking and enacting utopian possibilities.
The U.K. as a Technological Follower: Higher Education Expansion and the College Wage Premium
Authors: Blundell Richard , Green David A , Jin Wenchao 
Published: July 2021

Abstract
The proportion of U.K. people with university degrees tripled between 1993 and 2015. However, over the same period the time trend in the college wage premium has been extraordinarily flat. We show that these patterns cannot be explained by composition changes. Instead, we present a model in which firms choose between centralized and decentralized organizational forms and demonstrate that it can explain the main patterns. We also show the model has implications that differentiate it from both the exogenous skill-biased technological change model and the endogenous invention model, and that U.K. data fit with those implications. The result is a consistent picture of the transformation of the U.K. labour market in the last two decades.
Fetal programming effects of early weaning on subsequent parity calf performance
Authors: Oattes Jack L , Shao Taoqi , Henley Parker A , Shike Daniel W 
Published: July 2021

Abstract
Mature Simmental × Angus cows [n = 147; body weight (BW) = 590 ± 72 kg] were used to evaluate the effects of early weaning on subsequent parity calf growth performance and carcass characteristics. Cows were assigned to one of two treatments based on their previous calf’s weaning age: early wean (EW) or conventional wean (CW). Dams assigned to the EW treatment had calves previously weaned at 88 ± 6 d of age, whereas dams assigned to the CW treatment had calves previously weaned at 185 ± 6 d of age. Cow BW and body condition scores (BCS) were monitored during the experiment. All cows were managed as a common group from the onset of the experiment at breeding until final pregnancy check of their next production cycle 462 d later. All calves in the experiment were managed as one group and weaned at a single time point, then feedlot performance and carcass characteristics were evaluated. Initial cow BW was different (P &lt; 0.05), so it was included as a covariate for cow BW analysis. There was a treatment × date interaction (P &lt; 0.01) for cow BW and cow BCS. Cow BW was consistently greater for the EW treatment from day 39 to the end of the experiment (P &lt; 0.01). Cow BCS were not different at the onset of the experiment (P = 0.20), although after breeding and throughout lactation, BCS diverged between treatments and the EW treatment consistently had greater (P &lt; 0.01) BCS than the CW treatment throughout the entire subsequent lactation. Gestation length was not different (P = 0.21) between treatments, yet calf birth BW was greater (P = 0.05) for the EW treatment. Neither artificially inseminated pregnancy percentage nor overall pregnancy percentage was different between treatments (P ≥ 0.61). Despite the greater birth BW for the EW treatment and no difference (P = 0.25) in milk production, weaning BW was not different (P = 0.50) between treatments. Feedlot performance measures were not different (P ≥ 0.13) between treatments, including feedlot arrival weight, final BW, average daily gain, dry matter intake, and gain to feed. Final carcass characteristics were not different (P ≥ 0.33) between treatments, including dressing percentage, hot carcass weight, LM area, 12th rib fat thickness, kidney, pelvic, heart fat percentage, USDA yield grade, and marbling score. Thus, early weaning resulted in improved BW and BCS of cows as well as increased birth BW of subsequent calf, although that did not transpire into differences in postnatal growth performance or carcass traits.