bluuebunny/crossref_metadata_2025_split huggingface dataset:
Daily physical activity and trajectories of care service use among older adults: the HUNT4 Trondheim 70+ study
Authors: Ustad Astrid , Edwin Trine Holt , Melsæter Kjerstin Næss , Sverdrup Karen , Tangen Gro Gujord , Døhl Øystein , Thingstad Pernille , Vereijken Beatrix , Skjæret-Maroni Nina 
Published: February 2025

IntroductionUnderstanding factors that influence care service use is crucial for developing preventive strategies to maintain independence among older adults. In this study, we aimed to identify distinct trajectory groups of municipal care service use among community-dwelling older adults to determine whether daily physical activity is associated with future care service use.MethodsThis prospective cohort study included 981 community-dwelling older adults from the HUNT4 Trondheim 70+ study. At baseline, physical activity was assessed over seven consecutive days using two accelerometers attached to the thigh and lower back. An activity type machine learning model was used to classify the physical activity types: walking, standing, cycling, running, sitting, and lying. Municipal care service use was retrieved monthly from medical records for 3 years. Using group-based trajectory modeling, we identified distinct trajectories of care service use. Multinomial regression models adjusted for age, sex, education level, dementia, and physical performance were used to evaluate the associations between daily physical activity at baseline and care service group belonging.ResultsWe identified four distinct trajectory groups of municipal care service use, labeled steady low (72.7%), low increasing (9.0%), medium increasing (12.0%), and high increasing (6.3%). Daily time spent in total physical activity was not associated with trajectory group belonging when adjusted for age, sex, education level, dementia, and physical performance. However, more time spent walking, in bouts lasting longer than a minute, was associated with a reduced relative risk of belonging to the high increasing compared to the steady low group. Furthermore, age, physical performance, and dementia were all significantly associated with trajectory group belonging, and sex differences were observed. Compared to women, men had a reduced relative risk of belonging to the low increasing, medium increasing, or high increasing trajectory groups.ConclusionThis study identified four distinct trajectories of municipal care service use among older adults over 3 years. Total daily physical activity was not associated with trajectories of care service use, but more time spent walking in longer bouts was independently associated with lower care service use, even when adjusted for the strong predictors of physical performance, dementia diagnosis, and age.
Surrounding Residential Greenness and Health: Associations With Abdominal Obesity and Dyslipidemia. A Meta-Analysis of Cross-Sectional Studies
Authors: Marcilla-Toribio Irene , Bizzozero-Peroni Bruno , Notario-Pacheco Blanca , Cekrezi Shkelzen , Fernandez-Perez Martin , Perez-Moreno Ana , Diez-Fernandez Ana , Martinez-Andres Maria 
Published: February 2025

ObjectivesWe aimed to quantify the relationships of surrounding residential greenness with abdominal obesity and dyslipidemia.MethodsA systematic search was conducted in January 2024 through 5 electronic databases including Pubmed, Scopus, Web of Science, and CINHAL (Complete and GreenFILE). The DerSimonian and Laird method was used to calculate the pooled odds ratios (ORs) and their respective 95% confidence intervals (CIs). The study protocol was registered in PROSPERO (CRD42024528548).ResultsEleven cross-sectional studies involving 564,254 individuals with a mean age of 55.95 years were included. A significant inverse relationship was observed between increased surrounding greenness and lower odds of abdominal obesity (OR: 0.80; 95% CI: 0.70–0.91), elevated TG (OR: 0.97; 95% CI: 0.96–0.97), and low HDL-C levels (OR: 0.98; 95% CI: 0.95–1.00).ConclusionAbdominal obesity and elevated triglyceride levels could be reduced in the general adult population by increasing residential greenness. These findings underscore the importance of integrating greenness into urban planning and public health policies to promote healthier environments. Interventions such as the development of urban green spaces could play a crucial role in reducing cardiometabolic risk factors.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024528548
The epidemic process of tick-borne infections in Sverdlovsk region
Authors: Fedorova E. V. , Tretyakova N. N. , Slobodenyuk A. V. 
Published: February 2025

Objective. To identify characteristics of the epidemic process of tick-borne infections in Sverdlovskaya Oblast (Russia) over a multi-year period, using the municipality of Alapaevsk as a case study. Materials and methods. Based on the state statistical reports from 2014 to 2023, the present study examines the incidence of tick-borne viral encephalitis (TBVE), Lyme borreliosis (LB), and tick bites among the local population. Results. The incidence of tick-borne viral encephalitis was found to be higher than that of Lyme borreliosis in Sverdlovskaya Oblast and the municipality of Alapayevsk. Both TBVE and LB show an annual incidence pattern in the region. In the municipality of Alapayevsk, TBVE was not recorded in the years 2014, 2018, and 2023, while LB was not registered in 2015 and 2021. The incidence rates for TBVE fluctuated between 2.30/0000 and 15.5 0/0000, while LB incidence ranged from 2.20/0000 to 13.30/0000. In the structure of morbidity, urban population predominated for both TBVE and LB, accounting for 81–87 %, with a majority being males. Notably, no cases of TBVE were registered among children. Conclusion. Sverdlovskaya Oblast and the municipality of Alapayevsk appear to be a natural focus of infection and faces the ongoing challenge with the incidence of tick-borne viral encephalitis and Lyme borreliosis, given the annual occurrences of population seeking medical assistance due to tick bites. The epidemic process of TBVE and LB involves primarily the adult population, predominantly males. In certain years, a dominance of one of the two parasitic diseases (TBVE or LB) has been observed.
Metabolically-oriented effect of fucoidan from Sargassum feldmannii brown algae on the mda-mb-231 human breast cancer cells
Authors: Malyarenko O. S. , Zueva A. O. , Usoltseva R. V. , Silchenko A. S. , Ermakova S. P. 
Published: February 2025

Objective. To study the effect of fucoidan from brown algae S. feldmannii (SfF2) on the metabolism of MDA-MB-231 breast cancer cells. Materials and methods. The bioenergetic potential of MDA-MB-231 cells was assessed under the influence of various factors (insulin, epidermal growth factor, phorbol ester, and X-rays) stimulating tumor progression. The metabolically oriented effect of fucoidan SfF2 (200 µg/ml) on the colony formation process of MDA-MB-231 human breast cancer cells was determined using the soft agar method under normal conditions and under the influence of various carcinogenic factors. Results. Fucoidan from brown algae S. feldmannii was found to reduce the number of colonies of MDA-MB-231 cells induced by insulin, epidermal growth factor (EGF), and 12-O-tetradecanoyl-phorbol-13-acetate (TPA) by more than 50 % compared to control cells. Conclusion. The use of fucoidan as an adjunct to standard therapy appears to be a promising strategy for enhancing the efficacy of anticancer treatment.
Humoral and cellular factors of the mucosaal system of the respiratory tract in assessing the effectiveness of treatment of patients with chronic tonsillitis
Authors: Kurbanova A. Yu. , Vasilenko I. A. , Egorov V. I. 
Published: February 2025

Objective. To assess the efficacy of various types of comprehensive treatment for patients with chronic tonsillitis, using the dynamics of lysozyme, lactoferrin, secretory immunoglobulin A (sIgA), and NETosis products in smears from the surface of the palatine tonsil lacunae as criteria. Materials and methods. The study enrolled 120 patients aged 18–65 years diagnosed with chronic tonsillitis. All patients were divided into three groups of 40 individuals each. Group 1 patients underwent a two-stage vacuum and manual lavage of the palatine tonsils, followed by intralacunar administration of an oil solution of chlorophyllipt. In Group 2, the procedures were supplemented with exposure to low-intensity laser radiation. In Group 3, intralacunar administration of exogenous nitric oxide was additionally applied. The levels of humoral factors (lactoferrin, lysozyme, and serum immunoglobulin A [sIgA]) and cellular factors (products of neutrophil extracellular trap transformation) of the mucosal system of the respiratory tract were evaluated before treatment, and 1, 6, and 12 months after therapy. Statistical analysis was conducted using Statistica 12 software. The median, first and third quartiles of Me [LQ; UQ], mean value and standard deviation (M ± σ) were calculated. Statistical differences between groups were assessed using the Mann-Whitney U test and Fisher's exact test. A significance level of p < 0.05 was accepted for all analyses. Results. Statistically significant improvement in humoral factors (lactoferrin, lysozyme, sIgA) of the mucosal system was observed in the combined treatment groups utilizing physiotherapeutic methods. The proportion of patients with no NETosis products at 1 month after the course of therapy accounted for 27.5 %, 37.5 % and 40 %, at 12 months – 22.5 %, 40 % (p < 0.05) and 35 % (p < 0.05) against the initial 17.5 %, 20 % and 17.5 % in Groups 1, 2 and 3, respectively. In Group 1, the number of patients with moderate and high levels of NETosis products decreased by 10 %, 5 %, and 10 % (p < 0.05) in one, six, and twelve months after therapy, respectively; in Group 2, it reduced by 19 % (p < 0.05), 14.3 % (p < 0.05), and 33.3 % (p < 0.05); in Group 3, this number declined by 33.3 % (p < 0.05), 23.8 % (p < 0.05), and 47.4 % (p < 0.05), correspondingly. Conclusion. When selecting a conservative treatment algorithm, the advantages lie with a combined approach that includes a comprehensive irrigation-elimination regimen alongside physiotherapeutic methods, particularly laser therapy and nitric oxide therapy, the efficacy of which can be objectively confirmed by the dynamics of humoral and cellular factors of the mucosal system of the respiratory tract.
Osseointegration Acceleration of Dental Implants by Weak Direct Current
Authors: Ostapovich A. A. , Ivashenko S. V. , Shpak I. I. 
Published: February 2025

It is possible to improve the quality of treatment of patients using dental implants by strengthening the bone–dental implant connection with a weak direct current. Titanium electrodes simulating dental implants were used in the in vitro experiment. The electrodes were placed in collected human venous blood. In the experimental group, physiotherapy procedures were performed for 10 minutes using the developed device at a current of 15–20 μA. In the control group, titanium plates were placed in blood without electric current for 10 minutes. In the studied samples, the adhesion density of blood clots to the titanium plates, the thickness of blood clots, the number of platelets and erythrocytes were studied. It was found that the effect of an electric current of 15–20 μA on a blood clot through titanium plates contributes to thickening and compaction of blood clots on the surface of the electrodes. The number of red blood cells and platelets in the blood clot increases, which can have a positive effect on the process of osseointegration.
Interfacial bottom-up fabrication of ultrathin nanoporous films: techniques, characterization and applications
Authors: Ishizaki Yuya , Yamamoto Shunsuke , Nagano Shusaku , Mitsuishi Masaya 
Published: February 2025

Abstract
The bottom-up fabrication technique is one of the key technologies taking place conventional top-down approaches to create nanoporous (NP) thin film materials with tailorable nanostructures such as film thickness, film density, pore form, and pore size with nanometer (or sub-nanometer)-scale accuracy. This progress review specifically highlights bottom-up fabrication techniques using two-phase interfaces including solid–gas interfaces, solid–liquid interfaces, liquid–liquid interfaces, and gas–liquid interfaces by referring to recent publications. Moreover, experimental techniques to analyze nanostructures of NP thin film materials from well-ordered regular structures to non-periodic structures are introduced. Finally, some emerging potential applications and future perspectives of NP thin film materials are mentioned by using the latest literature.
A new danger for hop plants
Authors: Wenher O. , Fedorchuk N. , Shevchuk О. 
Published: February 2025

Goal. To scientifically substantiate the ecological and biological features of the development of gray mold and to establish the patterns of influence of various methods of gray mold control on hops.
Methods. Field — combined with visual observations and records; calculation and comparison — to determine the effectiveness of measures; laboratory to determine the content of biochemical components of cones; mathematical and statistical to identify the parameters of quantitative variability using dispersion and correlation-regression analysis to assess the reliability of the obtained results.
Results. In 2021—2023, monitoring and phytosanitary diagnostics of gray mold development patterns in the hop agrocenosis depending on climatic factors were carried out, and the level of harmfulness under the influence of various schemes and methods of regulating its prevalence was determined. The calculation of the effectiveness of methods of control and phytosanitary optimization of hops was carried out with the processing of the obtained data, the qualitative and quantitative indicators of the harvest were determined. It has been proven that mechanical damage contributes to damage to hop plants by the pathogen Botrytis cinerea Pers. et Fr. in the phase of growth of branches before flowering, and the signs appear mainly after its flowering in July. The conidial stage of the fungus predominates on the affected hop tissues. It was established that the spread of plant damage by the causative agent of gray mold of hop plantations of Ukraine was up to 40% in Zhytomyr region, and in Khmelnytskyi, Rivne and Lviv regions — up to 25% with an intensity of up to 29%. A selected group of selection numbers that are reliably more resistant to gray mold.
Conclusions. The regularities of the development of gray mold on hops depending on climatic factors have been established, as well as the level of harmfulness under the influence of various schemes and methods of regulating its prevalence, which ensure the preservation of the harvest up to 0.9 t/ ha of hop cones and 1.07% alpha-acid with a profit of up to UAH 265.000/ha.
Potato productivity during the growth biostimulator Aminostym usage
Authors: Gavrilyuk A. 
Published: February 2025

Goal. To calculate the effectiveness of the effect of stagnation of the biological growth stimulator Aminostim on the productivity of potato crops.
Methods. Field (sampling of plant material and its analysis). The study of the effectiveness of the frozen biological product was carried out on the basis of the Ukrainian Research Station for Plant Quarantine of the Institute of Plant Protection of NAAS for implementation in 2023—2024, on a natural infectious background and. The additional preparation was sprayed on vegetative plants (30 ml/10 l/1 sq.m.). Aminostim — contains amino acids that are easily digestible for plants (L-α-amino acids) — 134 g/l, nitrogen dioxide — 24 g/l, water-soluble phosphorus — 20 g/l, water-soluble potassium — 20 g/l, auxins — 10 g/l and cytokinins — 0.03 g/l. During the growing season, the first application of the preparation was carried out when the sprouts were compacted in the rows, and the next three times were applied through the skin after 12 days.
Results. The use of Aminostim on potato plants during the growing season had a positive effect on their productivity. The yield increase was 0.3 t/ha, which is 14% more than in the control. The number of tubers per bush is 2.7 pieces higher than in the control variant. Stagnation of the stimulant had a positive effect on the fractional composition of the bulbs. There was a change in the number of potato fraction by 7.6%, while the number of vegetable fraction increased by 12.5%. A large number of bulbs of the large fraction was lost without changes (8.8%).
Conclusions. The biological stimulant showed dryness similar to Alternaria of potato. The development of the disease in the Knyaginya variety under the stimulant treatment was 47.5%, while in the control it was 59.4%. From an economic point of view, the most promising is the use of the stimulant Aminostim in organic farming and in systems of integrated protection of potatoes against diseases.
INOVASI PRODUK APLIKASI MOBILE JKN VERSI 4.11.2 DI BPJS KESEHATAN CABANG BANDUNG
Authors: Diawati Prety , Najiba Hudawiyah Eba 
Published: February 2025

Di era digital yang berkembang pesat, masyarakat semakin menuntut layanan publik yang cepat, mudah, dan efisien, termasuk di sektor kesehatan. BPJS Kesehatan tidak luput dari tuntunan tersebut, dengan jumlah peserta Jaminan Kesehatan Nasional (JKN) mencapai 277.538.004 jiwa pada 31 Oktober 2024, menghadapi tantangan besar dalam memberikan pelayanan yang memadai. Data menunjukkan peningkatan kunjungan pasien ke fasilitas kesehatan dari 92,3 juta pada tahun 2014 menjadi 233,1 juta pada tahun 2021, kecuali penurunan pada tahun 2020 akibat pandemi COVID-19. Penelitian ini menyoroti masalah peningkatan kunjungan peserta BPJS Kesehatan ke fasilitas kesehatan atau kantor cabang. Untuk mengatasi hal ini, BPJS Kesehatan mengembangkan Inovasi Produk Aplikasi Mobile JKN Versi 4.11.2, yang bertujuan mempermudah akses informasi dan layanan administrasi bagi peserta. Inovasi produk ini memiliki lima karakteristik, yaitu keunggulan relatif (relative advantage), kesesuaian (compatibility), kompleksitas (complexity), ketercobaan (trialabillity), dan keterlihatan (observability). Tujuan penelitian ini untuk mengetahui gambaran hambatan dan solusinya yang terjadi pada Inovasi Produk Aplikasi Mobile JKN Versi 4.11.2, di BPJS Kesehatan Cabang Bandung. Menggunakan metode deskriptif dan pendekatan studi kasus, penelitian ini menemukan bahwa Inovasi Produk Aplikasi Mobile JKN 4.11.2, menunjukkan aplikasi ini berpotensi besar untuk diadopsi oleh masyarakat karena sifatnya yang inovatif.

Kata Kunci: Inovasi Produk.
El síndrome de burnout en los docentes de nivel básico en la modalidad a distancia
Authors: Sánchez-Calderón Claudia Angélica , Sánchez-Calderón Amelia Guadalupe 
Published: February 2025

La salud mental y física del docente ha sido por muchos años de vago interés para las autoridades educativas. El síndrome de burnout o síndrome del quemado es una condición que se ha generalizado en el ámbito laboral y que no exenta al docente que desarrolla una actividad profesional de tipo social.
El objetivo del presente artículo es mostrar las manifestaciones del Síndrome de Burnout en docentes que imparten clases a distancia en una institución de nivel básico en el Municipio de Toluca México. Se trata de una investigación de enfoque cualitativo, método fenomenológico y de tipo interpretativo. Se diseñó y validó una guía para emplear la técnica de entrevista a profundidad, la cual fue aplicada a cuatro docentes. Con los datos obtenidos se realizó el procedimiento de análisis de datos de codificación abierta y axial; lo que permitió la integración de categorías para su triangulación y posterior análisis.
De los resultados se obtuvieron las categorías 1. Agotamiento Emocional, en el cual se hicieron evidentes sentimientos de alegría, frustración, preocupación, cansancio físico y mental. 2. Despersonalización, a través de la cual se reveló que el docente se aproxima a los alumnos con límites y sin involucramiento; y 3. Manifestaciones de realización personal, donde los docentes reconocen y se apropian de sus metas, estableciendo diversas estrategias para lograr cumplirlas, aún sobre pasando los límites respecto a sus responsabilidades y funciones laborales.
Se concluye que el trabajo de docencia en modalidad a distancia, exponen manifestaciones del síndrome de burnout lo que decrementa su calidad de vida, exigiendo una atención inmediata por ser considerado un factor de riesgo laboral que afecta a la salud psicológica y física a los docentes; por lo que se recomienda fomentar programas y estrategias para la intervención remedial, así como promover una cultura de prevención ante este síndrome.
PELATIHAN PEMBUATAN MEDIA AUGMENTED REALITY MENGGUNAKAN SMARTPHONE ANDROID BAGI GURU-GURU IPA SMP DI KABUPATEN OGAN ILIR
Authors: Marlina Leni , Wiyono Ketang , Ismet Ismet , Helen Helen , Ramadhani Anisa , Mariam Mariam , Tiara Okta , Almafie M Rama , Jayasusena Ryan Faksi , Maisa Kamila Nada , Yuliarti Yanti 
Published: February 2025

Abstrak

Augmented Reality (AR) merevolusi proses pendidikan dan pembelajaran dengan mengintegrasikan elemen digital ke dalam data dunia nyata. Integrasi teknologi AR ke berbagai aspek kehidupan seperti hiburan, periklanan, pendidikan dan kesehatan diperkirakan akan terus mendorong perkembangan signifikan di masa depan. Tim MGMP IPA SMP Kabupaten Ogan Ilir meminta bantuan kepada Program Studi Magister Pendidikan Fisika FKIP untuk memberi pelatihan atau informasi Pelatihan Pembuatan Media Augmented reality. Metode kegiatan diberikan dalam bentuk pelatihan dan pendampingan yang dilaksanakan pada 26-27 September 2023 dan bertempat di SMPN 1 Indralaya Utara. Khalayak Sasaran diikuti sejumlah 18 guru SMP latar belakang mata pelajaran Ilmu Pengetahuan Alam. Hasil pelaksanaan PKM kepada masyarakat, seluruh peserta sangat puas dengan adanya pelatihan pembuatan media augmented reality menggunakan smartphone android bagi guru-guru IPA SMP di Kabupaten Ogan Ilir. Selain itu, hasil survei tersebut juga menunjukkan bahwa para peserta merasakan kebermanfaat secara langsung terkait hal-hal yang telah disampaikan dan juga menginginkan adanya keberlanjutan dari kegiatan.

Abstract
Augmented reality (AR) revolutionizes the education and learning process by integrating digital elements into real-world data. The integration of AR technology into various aspects of life such as entertainment, advertising, education and health is expected to continue to drive significant developments in the future. The Ogan Ilir Regency Junior High School Science MGMP team requested assistance from the FKIP Physics Education Master Study Program to provide training or information on Augmented reality Media Making Training. The activity method is provided in the form of training and mentoring which was held on September 26-27, 2023 and took place at SMPN 1 Indralaya Utara. The target audience was followed by 18 junior high school teachers with a background in Natural Science subjects. The results of the implementation of PKM to the community, all participants were very satisfied with the training on making augmented reality media using android smartphones for junior high school science teachers in Ogan Ilir Regency. In addition, the survey results also showed that the participants felt the benefits directly related to the things that had been delivered and also wanted the continuation of the activity.