bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of Self-Instructional Module on Knowledge Regarding Selected Habit Disorders in Children among Mothers of Preschooler
Authors: Badwaik Aditi , Maurya Archana 
Published: November 2021

Background: A child is unique individual. The childhood era is critical for the socialization process, which involves the transmission of attitudes, customs, and behaviour through the influence of family and community. The promotion and maintenance of a child's health is influenced by the family's cultural and religious beliefs, educational level, and lifestyle. Improved child health requires better education, nutrition, family planning, improved health behaviour, and increased use of health services. The form of the caregiver interaction has a significant impact on a child's behavioural development. Parents, especially women, who are emotionally present, sensitive, perceptive, and effective in satisfying their child's needs are more likely to have securely connected children who are more likely to meet crucial behavioral milestones as they grow up.
Objectives:

To assess the existing knowledge regarding selected habit disorders in children among mothers of preschooler.
To assess the effectiveness of self-instructional module on knowledge regarding selected habit disorders in children among mothers of preschooler.
To determine the posttest knowledge score regarding selected habit disorder in children among mothers of preschooler with demographic variables.

Methodology: A study will be based on Evaluatory research approach with one group pretest and posttest research design. The impact of self instructional module on knowledge regarding selected habit disorders in children among mothers of preschooler will be assessed using non probability convenient sampling technique. selected 60 mothers of preschooler will be assessed knowledge regarding selected habit disorder in children by structured questionnaires and then self instructional module will be given to the selected sample developed by researcher as intervention.
Expected Results: The aim of this study is to assess the effectiveness of self-instructional module on knowledge regarding selected habit disorders in children among mothers of preschooler. Self instructional module will be useful in improving the respondents' knowledge.
Visible Quantitative Methods for the Estimation of Furosemide in Pure form and Pharmaceutical Formulations
Authors: Saleem Basima A. A. , Hamdon Enaam A. , Majeed Sahbaa Y. 
Published: November 2021

Aims: Design of technical methods for the determination of Furosemide in its pure and pharmaceutical dosage form using spectral methods.
Study Design: planned and executed to estimate Furosemide by using Visible spectrophotometric in pure and pharmaceutical dosage form.
Place and Duration of Study: Laboratory of Analytical Research, chemistry department, college of Science, University of Mosul ,Mosul-Iraq, during the period of April 2021 to August 2021.
Methodology: Furosemide, the commercially known drug Lazix, which is important in the treatment of heart diseases and high blood pressure. This study was carried out using JASCO V – 630, double-beam computerized UV-Visible spectrophotometer, with 1 cm matched cell, and HANA pH meter was used for reported pH readings.
Results: The reaction between Furosemide and bromo-phenol blue, xylenol orange, and chromazorol S. The decreasing in the intensity of the resulted colored complex was measured using bromo-phenol blue, xylenol orange, While the increasing of the color intensity was measured in the method (C). These three methods were based on charge transfer reaction. The limits of Beer's law for method (A) 0.4-32µg. mL-1, method (B) 1-32 and method (C) were 0.8-32 depending on the level of concentration, while the values ​​of the molar absorption coefficient 1.4×104, 2.1×104 and 1.57×104 l.mol-1.cm-1 for the first, second and third method respectively. Sandel's significance also was calculated for these three methods, 0.0157 μg.cm-2 for the first method, 0.0236 μg.cm-2 for the second method, while the third method was 0.0210 μg.cm-2. The method has been successfully applied for the determination of furosemide in its pure form and in some of its pharmaceutical preparations
Conclusion: The proposed methods were validated in terms of linearity, range, Accuracy, precision, Specificity, Robustness. The proposed methods were successfully applied to the estimation of Furosemide in pharmaceutical dosage form, method (B) was experimentally considered as a best method depending on the best values of molar absorptivity, stability of the resulted complex, and the linearity of the method (B) .
Analysis of Healthcare Professional’s Knowledge and Attitude towards Telemedicine in Vijayawada, Andhra Pradesh
Authors: Dongre Prerana , Nimmagadda Aparna , Kulkarni Meenal , Jadhav Shivani 
Published: November 2021

Introduction: In India modern service delivery technologies like telemedicine are emerging promptly in healthcare sector. Successful implementation and utilization of novel technology hinges on several significant aspects together with knowledge, and attitude regarding technology and its user operating environment.
Aim: Primary objective of this study was to determine the knowledge and attitude of health professionals towards telemedicine in Vijayawada division of Andhra Pradesh state of India.
Methods: A randomized survey was conducted among healthcare professionals. A total of 123 respondents from medical and para-medical departments have participated in the study. A well-defined questionnaire was utilized to determine the knowledge and attitude of respondents about telemedicine. Data is entered and analysed using MS Excel 365 and SPSS 20. Pearson Correlation test was used to test the correlation between knowledge and attitude and Chi-Square test to assess the significant differences amongst gender and respondent’s knowledge, and between gender and attitude of respondents about telemedicine. < 0.05 was considered as significant P-value.
Results: 52.57% respondents had good knowledge level, of which 54.34% were males, there was no significant difference between respondent’s gender and their level knowledge with respect to telemedicine. Regarding attitude towards telemedicine 57.45% respondents had positive attitude towards telemedicine. Also, there was no significant difference between gender and attitude of respondents towards telemedicine. The Pearson Correlation value 0.699 indicates that a positive correlation exists between Knowledge and Attitude.
Conclusion: Outcomes of the analysis indicate that though the respondent’s knowledge about telemedicine is average. Majority of respondents had positive attitude about telemedicine. COVID 19 has brought more light on telemedicine, and at this period it is very important to consider creating awareness and training the users as abundant knowledge and optimistic attitude towards the technology are significant factors to for any healthcare professional to implement and practice telemedicine.
Effect of workplace dietary intervention on salt intake and sodium-to-potassium ratio of Japanese employees: A quasi-experimental study
Authors: Sakaguchi Keiko , Takemi Yukari , Hayashi Fumi , Koiwai Kaori , Nakamura Masakazu 
Published: November 2021

Abstract

Objectives
Excess salt intake is a major risk factor for hypertension and cardiovascular disease. Modifying workplace environments has been recognized to be important for reducing salt intake. However, studies examining the effects of improving the workplace environment regarding salt reduction are limited. This study aimed to evaluate the effects of workplace dietary intervention on employees’ salt intake and sodium-to-potassium (Na/K) ratio.

Methods
A quasi-experimental study was conducted. Two small business establishments in Saitama Prefecture, Japan, were allocated as the intervention (n = 69) and comparison (n = 68) workplaces, respectively. The 1-year intervention involving healthy lunch and nutrition education was implemented in the intervention workplace. Spot urine samples, physical assessments, and self-administered questionnaire data were collected at baseline, 6 months, and 1 year after the start of the intervention. Analysis of covariance was conducted to investigate differences in the salt intake or Na/K ratio between the study workplaces at year 1. Educational status and rotating work schedules were included as covariates.

Results
Salt intake in the intervention workplace decreased significantly from 10.7 to 9.3 g (−1.4 g change; 95% confidence interval [CI]: “−2.4, −0.5”). The adjusted difference in changes in salt intake between workplaces was statistically significant (−3.7 g change; 95% CI: “−5.2, −2.3”). Although no significant change was observed in the Na/K ratio in the intervention workplace (3.37–3.08; −0.29 change; 95% CI: “−0.59, 0.01”), the adjusted difference in changes between the workplaces was statistically significant (−0.60 change; 95% CI: “−1.03, −0.17”).

Conclusions
Providing healthy lunch and nutrition education may be effective approaches to reduce employees’ salt intake and Na/K ratio.
Transcriptome analysis of collagen VI‐related muscular dystrophy muscle biopsies
Authors: Guadagnin Eleonora , Mohassel Payam , Johnson Kory R. , Yang Lin , Santi Mariarita , Uapinyoying Prech , Dastgir Jahannaz , Hu Ying , Dillmann Allissa , Cookson Mark R. , Foley A. Reghan , Bönnemann Carsten G. 
Published: November 2021

AbstractObjectiveTo define the transcriptomic changes responsible for the histologic alterations in skeletal muscle and their progression in collagen VI‐related muscular dystrophy (COL6‐RD).MethodsCOL6‐RD patient muscle biopsies were stratified into three groups based on the overall level of pathologic severity considering degrees of fibrosis, muscle fiber atrophy, and fatty replacement of muscle tissue. Using microarray and RNA‐Seq, we then performed global gene expression profiling on the same muscle biopsies and compared their transcriptome with age‐ and sex‐matched controls.ResultsCOL6‐RD muscle biopsy transcriptomes as a group revealed prominent upregulation of muscle extracellular matrix component genes and the downregulation of skeletal muscle and mitochondrion‐specific genes. Upregulation of the TGFβ pathway was the most conspicuous change across all biopsies and was fully evident even in the mildest/earliest histological group. There was no difference in the overall transcriptional signature between the different histologic groups but polyserial analysis identified relative changes along with COL6‐RD histological severity.InterpretationOverall, our study establishes the prominent dysregulation of extracellular matrix genes, TGFβ signaling, and its downstream cellular pathways at the transcriptomic level in COL6‐RD muscle.
All‐3D‐Printed, Flexible, and Hybrid Wearable Bioelectronic Tactile Sensors Using Biocompatible Nanocomposites for Health Monitoring
Authors: Yi Qian , Najafikhoshnoo Sahar , Das Prativa , Noh Sangjun , Hoang Emily , Kim Taeil , Esfandyarpour Rahim 
Published: November 2021

AbstractPhysiological signals contain a wealth of personal health information which needs continuous monitoring for early detection of disease‐induced physiological irregularities and can be established as a potential approach to developing personalized healthcare devices. However, it is restricted by the lack of cost‐effective, precise, sensitive, and biocompatible flexible wearable sensors that are rapidly, reliably, and cost‐effectively are integratable. Here the work is reported on the development of novel, multimaterial, and multilayer all‐3D‐printed nanocomposite‐based (M2A3DNC) microengineered, flexible, hybrid, and soft wearable pressure sensors to record sensitive and multiple physiological signals for real‐time human health monitoring. By applying the intrinsic property of extrusion 3D printing, the conductive layers as well as the hemicylinder microstructure dielectric layer are directly 3D printed by optimizing the moving path of a nozzle, with air voids formation after assembling to enhance the compressibility of the active layer in our sensors. The microengineered sensors exhibit a very low detection limit, rapid response time, a repeatable and reproducible mechanical property with matching modulus with human skin (0.57–3.7 MPa) while offering intimate contact to the skin, excellent biocompatibility, and high mechanical compressibility in the active layer which leads to significantly high sensitivity. Thus, the proposed 3D printed cost‐effective M2A3DNC sensors pave a novel path to develop a highly compressible microstructured device with high sensitivity and low detection limit in a time‐effective manner with demonstrated application in real‐time health monitoring and envision further applicability in robotics tactile sensing interfaces.
Highly Selective High‐Speed Circularly Polarized Photodiodes Based on π‐Conjugated Polymers
Authors: Ward Matthew D. , Wade Jessica , Shi Xingyuan , Nelson Jenny , Campbell Alasdair J. , Fuchter Matthew J. 
Published: November 2021

AbstractChiral π‐conjugated molecular systems that are intrinsically sensitive to the handedness of circularly polarized (CP) light potentially allow for miniaturized, low‐cost CP detection devices. Such devices promise to transform several technologies, including biosensing, quantum optics, and communication of data encrypted by exploiting the spin angular momentum of light. Here a simple, bilayer organic photodiode (CP OPD) comprising an achiral π‐conjugated polymer–chiral additive blend as the electron donor layer and an achiral C60 electron acceptor layer is realized. These devices exhibit considerable photocurrent dissymmetry gph, with absolute values as high as 0.85 and dark currents as low as 10 pA. Impressively, they showcase a linear dynamic range of 80 dB, and rise and fall times of ≈7 µs, which significantly outperforms all previously reported CP selective photodetectors. Mechanistically, it is shown that the gph is sensitive to the thickness of both the chiral donor and achiral acceptor layers and that a trade‐off exists between the external quantum efficiency and gph. The fast‐switching speeds of these devices, coupled with their large dynamic range and highly selective response to CP light, opens up the possibility of their direct application in CP sensing and optical communications.
Evidence linking life‐form to a major shift in diversification rate inCrassula
Authors: Lu Meng , Fradera‐Soler Marc , Forest Félix , Barraclough Timothy G. , Grace Olwen M. 
Published: November 2021

AbstractPremisePlants have evolved different ecological strategies in response to environmental challenges, and a higher lability of such strategies is more common in plant groups that adapt to various niches.Crassula(Crassulaceae), occurring in varied mesic to xeric habitats, exhibits a remarkable diversity of life‐forms. However, whether any particular life‐form trait has shaped species diversification inCrassulahas remained unexplored. This study aims to investigate diversification patterns withinCrassulaand identify potential links to its life‐form evolution.MethodsA phylogenetic tree of 140Crassulataxa was reconstructed using plastid and nuclear loci and dated based on the nuclear DNA information only. We reconstructed ancestral life‐form characters to estimate the evolutionary trends of ecophysiological change, and subsequently estimated net diversification rates. Multiple diversification models were applied to examine the association between certain life‐forms and net diversification rates.ResultsOur findings confirm a radiation withinCrassulain the last 10 million years. A configuration of net diversification rate shifts was detected, which coincides with the emergence of a speciose lineage during the late Miocene. The results of ancestral state reconstruction demonstrate a high lability of life‐forms inCrassula, and the trait‐dependent diversification analyses revealed that the increased diversification is strongly associated with a compact growth form.ConclusionsTransitions between life‐forms inCrassulaseem to have driven adaptation and shaped diversification of this genus across various habitats. The diversification patterns we inferred are similar to those observed in other major succulent lineages, with the most‐speciose clades originating in the late Miocene.
Pulmonary vascular resistance and compliance in individuals with trisomy 18
Authors: Hatai Eriko , Muneuchi Jun , Sugitani Yuichiro , Doi Hirohito , Furuta Takashi , Ezaki Hiroki , Kobayashi Masaru , Sato Rie , Watanabe Mamie 
Published: November 2021

AbstractIndividuals with trisomy 18 (T18) usually have congenital heart disease, often with pulmonary hypertension, which is associated with poor outcomes. This study aimed to explore the characteristics of pulmonary circulation including pulmonary vascular resistance (Rp) and compliance (Cp) among them. We retrospectively reviewed cardiac catheterization data in subjects with T18, trisomy 21 (T21), and without chromosomal anomaly (control group) who were referred due to heart failure associated with ventricular septal defect between 2000 and 2020. Pulmonary hemodynamic parameters including Rp and Cp were compared between these groups. We studied 20 subjects with T18, 88 subjects with T21, and 240 control subjects. There was no significant difference in age (T18: 4.6 [3.0–6. 9] vs. T21: 2.8 [1.9–4.0] vs. control: 2.9 [1.6–3.2] months, p = 0.06) and mean pulmonary arterial pressure (T18: 41 [33–49] vs. T21: 35 [30–41] vs. control: 36 [28–43] mmHg, p = 0.121) between the groups. The pulmonary to systemic blood flow ratio (Qp/Qs) (p = 0.983), Rp (p = 0.449), and Cp (p = 0.195) did not differ between T18 and control groups. However, Qp/Qs and Cp in T18 group were significantly greater than that in T21 group (T18: Qp/Qs: 3.4 [2.3–5.2] vs. T: 21 2.3 [1.7–3.7], p = 0.001. Cp: 3.5 [2.3–5.5] vs. 2.3 [1.6–3.1] mmHg/mL/m2, p = 0.007), while Rp was identical between the groups (T18: 2.0 [1.6–3.3] vs. T21: 2.3 [1.7–3.7], p = 0.386). The pulmonary circulation in T18 subjects differed from that observed in T21 subjects, and identical to that observed in control subjects. Pulmonary hypertension is expected to be normalized after reasonable corrective surgery in T18 patients with congenital heart disease.
Fabrication of an novel NiCo‐based bimetallic hydroxide encapsulated with polyphosphazene with simultaneously improved the flame retardancy and smoke suppression for polypropylene
Authors: Tian Xian‐Yao , Xu Sheng , Wu Kun , Zeng Hong‐Yan , Hu Jie , Guo Yi‐Hui 
Published: November 2021

AbstractThe polyphosphazene (PZN) with dual functions of “surface modifier” and “flame‐retarded synergistic agent” was introduced as the “shell” in order to improve the compatibility and flame retardancy property of NiCo‐based bimetallic hydroxide (NiCo‐BH). In this study, a novel core‐shell nanostructures flame retardants (PZN@NiCo‐BH) was synthesized, the resulting PZN@NiCo‐BH was further incorporated into PP to investigate the mechanical property, flame retardancy and smoke suppression performance. Chemical structure and morphology of PZN@NiCo‐BH were characterized by XRD, FT‐IR, SEM, TEM, WCA and TG‐DTG, and the results have shown the successful preparation of the well‐designed PZN@NiCo‐BH. Moreover, LOI, UL‐94 and cone calorimetry measurements results further confirmed the superb flame retardancy and smoke suppression of the synthesized PP/PZN@NiCo‐BH composites with a LOI value of 29.5% in the UL‐94 V‐0 rating, and 56.3% reduction in total smoke production (TSP). Meanwhile, based on the analysis of the combustion residues, possible mechanism of flame retardancy was also proposed.
Study on ethanol resistance stability and adhesion properties of polyacrylate latex for PE or BOPP film inks
Authors: Yu Shan , Du Ying , Chen Yongming , Zhang Xinyi , Li Xiaoyu , Wang Haiqiao 
Published: November 2021

AbstractWaterborne inks based on the polyacrylate latex typically suffer from poor ethanol resistance and low adhesion on the PE or BOPP films. In this contribution, self‐crosslinkable polyacrylate latex binders with core‐shell structure and diacetone acrylamide (DAAM)/adipic acid dihydrazide (ADH) crosslinking agent for the application in the PE (polyethylene) or BOPP (Biaxially oriented polypropylene) film inks were synthesized. The effect of DAAM distribution in latex particles on ethanol resistance stability and the adhesion on the PE and BOPP thin films of the latexes and the corresponding inks was studied. Also, two functional monomers, isobornyl acrylate (IBOA) and acrylamide (AM) were introduced into the polyacrylate, respectively, to investigate their effect on the adhesion of the latexes and the inks on the PE and BOPP films. The results demonstrated that the more DAAM distributed in the core layer of the latex particles, the better the ethanol resistance, but the weaker the initial adhesion on the BOPP and PE thin films and the lower crosslinking degree of the latexes and the relative inks. However, the difference in cross‐linking degree and adhesion between the latex film with DAAM located within the shell part and that of DAAM located in the shell part keeps reducing with the prolongation of film‐forming time. Thus, when half of the DAAM is in the shell layer of latex particles, the latexes and the corresponding inks possess a balanced comprehensive property. The introduction of IBOA into polyacrylate is beneficial for improving the adhesion on both the BOPP and PE films of the inks due to the reduced surface tension of the latex. However, AM is only effective on the PE film, which may be due to the structural similarity of AM to erucate amide and oleate amide contained in the PE film, improving interaction between ink and the PE film.
Global dissipativity and adaptive synchronization for fractional‐order time‐delayed genetic regulatory networks
Authors: Zhang Zizhen , Zhang Weishi , Anbalagan Pratap , Arjunan Mani Mallika 
Published: November 2021

AbstractThis manuscript examines global dissipativity and synchronization criteria for time‐delayed fractional‐order gene regulatory networks (FGRNs). The Lyapunov stability theory is used to examine a class of FGRNs with delay arguments that are inspired by the integer‐order delayed gene regulatory network model. Some sufficient criteria are established using the fractional‐order comparison principle and stability theorem for fractional‐order time‐delayed systems to ensure the global dissipativity solution of FGRNs with both feedback regulation and translation time delays. Furthermore, for FGRNs, the global asymptotic synchronization condition is accomplished by constructing an adaptive delayed feedback control method for the master–slave system. Finally, two numerical examples are provided to demonstrate the applicability and superiority of the conclusions obtained.
Multifrequency study of gigahertz‐peaked spectrum sources with RATAN‐600
Authors: Sotnikova Yulia , Mufakharov Timur , Mingaliev Marat , Mikhailov Alexander 
Published: November 2021

AbstractWe report the radio continuum properties for several samples of peaked spectrum (PS) radio sources. Broadband spectra of the objects were analyzed using the RATAN‐600 six‐frequency (1.2–22 GHz) observations and available literature data, obtained on a time scale of 20–30 years. We discuss statistical differences in radio properties for several AGN types with peaked spectra and focus on PS quasars at high redshifts (). We confirm that a relatively small fraction (1–2%) of bright PS sources can be considered genuine gigahertz‐peaked spectrums (GPSs) when they have been monitored densely and for a long time. The contamination of GPS source samples by blazars is getting stronger as the redshift increases, and we confirm that it is underestimated due to lack of systematic multifrequency observations.