bluuebunny/crossref_metadata_2025_split huggingface dataset:
RETURN ON ASSETS DAN DETERMINASI FAKTOR-FAKTOR YANG MEMPENGARUHINYA (STUDI PADA BUS NON DEVISA PERIODE 2018-2019)
Authors: Azizah Nikmatul , Agung Eko Purwana  
Published: December 2021

Return on Assets (ROA) is important for banks. This is because ROA can be used to measure a bank's ability to make profits in general. In the period 2018-2019 there were problems in the financial statements where when Murabahah Financing and Revenue Sharing Financing increased ROA decreased and when NOM increased ROA decreased. The purpose of this study tested the effect of murabahah financing, revenue sharing financing and NOM on ROA on Bank Uumum Syariah Non-Foreign Exchange. The novelty of this research is in the form of research methods used, which have never previously been used with murabahah financing variables, revenue sharing financing and NOM together. This research is a type of quantitative research with panel data regression methods. The sample used amounted to 4 from Non-Foreign Exchange Sharia Commercial Banks using quarterly data for the period 2018-2019. The findings in this study stated that murabahah financing, revenue sharing and NOM partially had no effect on ROA. However, together murabahah financing, revenue sharing financing and NOM affect ROA. The amount of influence given by the three variables to the ROA is 95.34%. Non-Foreign Exchange Sharia Commercial Bank can increase bank profits and maintain bank stability in financing and investment by increasing the three variables together.
Return on Assets (ROA) merupakan sesuatu yang penting bagi Bank. Hal ini dikarenakan ROA dapat digunakan untuk mengukur kemampuan bank dalam memperoleh keuntungan secara umum. Pada periode tahun 2018-2019 ditemukan permasalahan pada laporan keuangan dimana ketika Pembiayaan Murabahah dan Pembiayaan Bagi Hasil meningkat ROA menurun dan ketika NOM meningkat ROA mengalami penurunan. Tujuan penelitian ini menguji pengaruh pembiayaan murabahah, pembiayaan bagi hasil dan NOM terhadap ROA pada Bank Uumum Syariah Non Devisa. Kebaruan dari penelitian ini berupa metode penelitian yang digunakan, yang sebelumnya belum pernah digunakan dengan variabel pembiayaan murabahah, pembiayaan bagi hasil dan NOM secara bersama-sama. Penelitian ini berjenis penelitian kuantitatif dengan metode regresi data panel. Sampel yang digunakan berjumlah 4 dari Bank Umum Syariah Non Devisa dengan menggunakan data triwulan periode 2018-2019. Hasil penemuan dalam penelitian ini menyatakan bahwa pembiayaan murabahah, pembiyaan bagi hasil dan NOM secara parsial tidak berpengaruh terhadap ROA. Akan tetapi secara bersama-sama pembiayaan murabahah, pembiayaan bagi hasil dan NOM berpengaruh terhadap ROA. Besarnya perngaruh yang diberikan ketiga varibel tersebut terhadap ROA sebesar 95,34%. Bank Umum Syariah Non Devisa dapat meningkatkan keuntungan bank dan menjaga kestabilan bank dalam melakukan pembiayaan maupun investasi dengan meningkatkan ketiga variable tersebut secara bersama-sama.
ANALISIS BUSINESS PLAN PELAKU UMKM DI KECAMATAN MLARAK
Authors: Moh. Zaenal Abidin  
Published: December 2021

Entrepreneurship is an activity to meet the needs of human life. With the existence of entrepreneurship, unemployment can be reduced, considering that in Indonesia the unemployment rate is very high. Especially with the Covid-19 outbreak, the unemployment rate has increased. In starting a business, careful planning is needed, so that the business we run is in accordance with the goals and expectations we want. In addition, the existence of a business plan can make it easier to evaluate the shortcomings of the business that we are running. Therefore business planning lies at the very top before doing or starting a business. The business plan or business plan includes a vision and mission, an overview of the company, marketing, goods and services produced, efforts to increase sales and capital.

Berwirausaha merupakan kegiatan untuk memenuhi kebutuhan hidup manusia. Dengan adanya kewirausahaan pengangguran dapat berkurang, mengingat di Indonesia tingkat pengangguran yang sangat tinggi. Terlebih dengan adanya wabah covid-19 ini, tingkat pengangguran meningkat. Dalam memulai sebuah usaha maka perlu perencanaan yang matang, agar usaha yang kita jalankan sesuai dengan tujuan dan harapan yang kita inginkan. Selain itu dengan adanya perencanaan usaha dapat mempermudah dalam mengevaluasi kekurangan terhadap usaha yang sedang kita jalankan. Oleh karena itu perencanaan usaha terletak pada posisi paling atas sebelum melakukan atau mengawali sebuah usaha. Dalam business plan atau perencanaan usaha didalamnya mencangkup visi dan misi, gambaran tentang perusahaan, pemasaran, barang dan jasa yang dihasilkan, usaha untuk meningkatkan penjualan dan permodalan.
Analytical Modeling of Wax Plug Transportation during Pipeline Pigging Using a Foam Pig
Authors: Gao Xuedong , Huang Qiyu , Zhang Xun , Zhang Yu 
Published: December 2021

Summary
In our previous article (Gao et al. 2020), a mathematical model including elastic and yield components but not viscous component was developed to predict the wax plug transportation force. In this work, an analytical model was developed to calculate the wax plug transportation force, and the viscous component was introduced into the analytical model to capture some of the time effects. In this analytical model, the viscoelastic behavior of the wax deposit was characterized by a three-parameter model, formulated by adding an additional spring element to the Kelvin-Voight model. The Laplace transformation was used to solve the model. According to the calculated results of the analytical model, the transportation force of the wax plug was observed to slightly increase with time and then tended to level off. To obtain a parameter in the model and verify the model, the pigging experiments were conducted using foam pigs. During the pigging process of the foam pig, the wax plug transportation force in a five-phase wax removal profile was determined by taking the steady wax breaking force from the resistive force of the wax layer. Moreover, the linear increase of the wax plug transportation force per unit contact area with the shear strength of the wax layer was found, as described by the functional relationship in the analytical model. The interfacial lubrication coefficient calculated from the experimental data based on the analytical model is between the coefficient for diesel-prepared deposits and coefficient for oil-A-prepared deposits. Experimental verification results show that the average relative error of the model is 12.47%. Field implication was proposed to illustrate the application of the model and the formation condition of the wax blockage.
Analysis of Mixed Water Source for Urban Underground Water Pipe Leakage by Using Water Geochemistry Model Calculation
Authors: Wu Dun , wei chao , li yunfei 
Published: December 2021

Abstract
China is a country short of water resources, and the leakage of urban water pipe network not only aggravates the current situation of water shortage, but also causes major accidents such as ground collapse, so it is of great significance to study the discrimination of urban underground pipe leakage. In this paper, the conventional ions and hydrogen and oxygen isotopes of water samples are determined by ion chromatograph and inductively coupled plasma mass spectrometer, and the characteristic factors are selected by cluster analysis and principal component analysis, and the mixed water discrimination model based on conventional ions is established According to the difference of hydrogen and oxygen isotope content between buried pipe water and groundwater, a discrimination model based on hydrogen and oxygen isotope is established, and the two models are combined to discriminate the leakage of buried pipe. The results show that, in terms of conventional ion content characteristics, the water in the pipe network is high in K++Na+ and Cl−, while the shallow groundwater near the pipe network is low in K++Na+ and Cl−, and the accuracy of the discriminant model based on conventional ions reaches 87.5%. In the aspect of hydrogen and oxygen isotope content characteristics, the water in the pipe network is closer to the precipitation line than the shallow groundwater, and establishing a discriminant model based on hydrogen and oxygen isotope can determine the leakage of buried pipes. This study provides a scientific basis for judging the leakage of urban underground pipes.
Comparison of a Biosensor and a Commercial UV-Visible Method for Measuring Hexavalent Chromium in Liquid Medium
Authors: Avellaneda Melany , Mafla Santiago Xavier , Mera Moraima 
Published: December 2021

Abstract
The objective of the research was to contrast two methods for the quantification of hexavalent chromium. The first method is the biosensor that from the gene transformation of the cells of Escherichia coli, was incorporated by electroporation the plasmid pTOP Blunt V2, synthesized with luxA genes that provides luminescence through the catalytic activity of the luciferase top and chr genes that give the bacteria resistance to chromium. The second method is the application of the UV-visible colorimetric technique. Chromium was analysed at different concentrations, from 0.05 mg l−1 (maximum allowable limit for human consumption); 0.1 mg l−1; 0.2 mg l−1; 0.4 mg l−1; 0.8 mg l−1 and 1 mg l−1 with 5 replicates, subsequent to this, the two methods of chromium analysis were applied in river samples, thus obtaining that the biosensor in concentrations of 2x106 CFU of E. coli, has a margin of error of 1.4%, a result derived from the coefficient of determination of the absorbance of chromium, unlike the UV-visible method with the colorimetric equipment, which presented a reading error of 3.9%.
Spatiotemporal Diurnal Modulation Characteristic of Wind Speed and Power Generation Revealed by Its Actual Measurement Data Information Processing
Authors: Wan Jie , Fan Shuangshuang , Yao Kun , Han Ke , E Peng , Yu Jilai 
Published: December 2021

Abstract
Atmospheric turbulence is an intrinsic factor that causes uncertainty of wind speed and its power generation by wind turbine. The research of atmospheric turbulence characteristics of wind farms can be used to reduce this uncertainty. In this paper, enough measurement data getting from actual wind farms is used for information processing to quantitatively analyze the daily variation of wind speed and its power output characteristics. Furthermore, the concept of spatiotemporal diurnal modulation characteristics of atmospheric turbulence is proposed with a global scope, which is an intrinsic property of wind. Besides the daily weather processes, the average hourly wind speed has a short-term modulation effect on its turbulence and provides a modulation characteristic on wind speed uncertainty. Moreover, the long-term modulation process is affected by seasonal and regional factors, indicating that it has spatiotemporal characteristics. This atmospheric turbulence characteristic has similar effects on characteristic description parameters. However, the characteristics description parameters of wind speed and wind power variation fail to reflect such intrinsic characteristics that are not affected by the spatiotemporal diurnal modulation characteristics of atmospheric turbulence. This indicates that they do not have diurnal characteristics. Finally, the application of spatiotemporal diurnal modulation characteristics on the evaluation of frequency control in power systems is discussed. The results show that this method can effectively improve the power generation quality of large-scale wind power.
Natural and Anthropogenic Sources of Cadmium in Cacao Crop Soils in Santander, Colombia
Authors: Joya-Barrero Valentina , Huguet Carme , Pearse Jillian 
Published: December 2021

Abstract
Cadmium (Cd) levels in cacao products from Santander, the main producing area in Colombia, are well above those permitted for export of cocoa products and may pose a potential health hazard. High Cd in cacao is related to the high content of the metal in beans, which in turn is linked to high concentrations of Cd in soils. Geochemical and petrographic analyses of fertilizer, soil and rock samples from three farms were carried out to determine the sources of Cd and soil characteristics that can affect its bioavailability, in order to identify strategies that may reduce Cd in cocoa. Autochthonous natural sources determine the Cd concentration in soils, with a high correlation between elevated Cd in sedimentary parental rocks and soil metal levels. While no industrial or mining inputs were present, an organic fertilizer was identified as a great allochthonous source of Cd in soils. High levels in the fertilizer were probably due to bioaccumulation of the element, since it was sourced from animals in the same area. The addition of crop waste to fertilize the soil may further contribute bioavailable Cd. Even though the pH range, high OM content and presence of Mn and K all diminish bioavailability, the high metal content in the farm soils still results in significant uptake by the cocoa plants and accumulation in the beans. We suggest that phytoremediation and biological amendments, as well as testing of fertilizers before application, could all be cost-effective solutions to reduce Cd levels in the final product.
Genomic Features of Chinese Small Cell Lung Cancer
Authors: Liu Jun , Zhao Zhuxiang , Li Binkai , Zhao Ziwen 
Published: December 2021

Abstract
Background: Small cell lung cancer (SCLC) is an aggressive disease with poor survival. Although molecular and clinical characteristics have been established for SCLC in western patients, limited investigation has been performed for Chinese SCLC patients.Objective: In this study, we investigated the genomic features of Chinese SCLC patients.Methods: A total of 75 SCLC patients were enrolled. Genomic alterations in 618 selected genes were analyzed by targeted next-generation sequencing.Results: Here, we showed that TP53 (77.30%) and RB1 (30.70%) were the most prevalent genes, followed by KMT2D, ALK, LRP1B, EGFR, NOTCH3, AR, CREBBP, ROS1, and BRCA2. And the most common genetic alterations were enriched in the cell cycle signaling pathway (84.00%) of Chinese SCLC patients. DNA damage repair (DDR) pathway analysis showed that the most frequently enriched DDR pathways were fanconi anaemia (FA, 29.41%) and homology recombination (HR, 21.57%). Notably, 9.33% SCLC patients in our cohort had pathogenic or likely pathogenic germline gene variants. Compared with the U Cologne cohort, a higher prevalence in EGFR, AR, BRCA2, TSC1, ATXN3, MET, MSH2, ERBB3 and FOXA1 were found in our cohort; while compared to the data from the Johns Hopkins cohort, a higher mutated frequency in TP53, KMT2D, ALK, and EGFR were found in our cohort. Moreover, a significant association was found between high tumor mutation burden (TMB) and mutations involved in TP53, CREBBP, EPHA3, KMT2D, ALK and RB1. Approximately 33.33% of patients with SCLC harbored at least one actionable alteration annotated by OncoKB, of which one patient had alterations of level 1; seventeen patients had level 3; fifteen patients possessed level 4.Conclusion: Our data might provide an insightful meaning in targeted therapy for Chinese SCLC patients.
Evaluation of Levetiracetam for Early Post-Traumatic Seizure Prophylaxis: A Level II Trauma Center Experience
Authors: Amin Timothy A. , Nerenberg Steven F. , Elsawy Osama A. , Wang Antai , Johnston Jackie P. 
Published: December 2021

Abstract
Background: Traumatic brain injury (TBI) can induce early or late post-traumatic seizures (PTS). While PTS incidence is low, prophylaxis is used despite a lack of consensus on agent or duration. Levetiracetam (LEV) for early PTS prophylaxis is preferred due to its safety and efficacy. The purpose of this study was to evaluate LEV for early PTS prophylaxis.Methods: A single-center, retrospective chart review of TBI patients > 18 years who received LEV for early PTS prophylaxis between August 2018 - July 2019. The primary outcome was LEV duration. Secondary outcomes were incidence of seizure, intensive care unit (ICU) and hospital length of stay (LOS).Results: Of the 137 included, mean age was 59±20 years and 69.3% were male. The mean admission GCS was 13±4 and 77.4% had mild TBI. Median LEV duration was 7 (IQR 4-10) days and 13.9% met recommended 7-day duration. Those prescribed LEV > 7 days had more than twice the median LEV duration than those prescribed ≤ 7 days (10.25 (8.5-15.5) vs 4 (1.5-4.5) days, p < 0.0001). EEG-confirmed PTS occurred in 2.2%, with an early PTS incidence of 0.73%. Median ICU and hospital LOS were 2 (IQR 1-7) and 7 (IQR 3-16) days, respectively. Conclusions: The incidence of PTS was low as most patients in our study had mild or moderate TBI. Early PTS prophylaxis with LEV for 7 days is appropriate, although the majority of patients did not meet the recommended duration. Efforts to standardize and implement PTS prophylaxis protocols are needed.
Psychometric Properties and Hidden Dimensionality of the Sinhala Version of End Stage Renal Disease Adherence Questionnaire (SINESRD-AQ) Among Patients Receiving Haemodialysis in a Selected Hospital in Sri Lanka
Authors: Lasanthika Chalani , Wanigasuriya Kamani , Hettiaratchi Usha , Amarasekara Thamara , Goonewardena Sampatha 
Published: December 2021

Abstract
BackgroundAdherence to a complex therapeutic regimen is crucial to maintain the quality of life of patients receiving haemodialysis. End Stage Renal Disease Adherence Questionnaire (ESRD-AQ) is a valid and most widely used instrument to assess all dimensions of treatment adherence among patients receiving in-center haemodialysis. Though the precise evaluation is fundamental, availability of valid and reliable instruments to evaluate treatment adherence is limited in Sri Lanka. Therefore, the purpose of this study was to evaluate the psychometric properties of Sinhala translated version of ESRD-AQ.MethodsThe translation and cultural adaptation of ESRD-AQ underwent forward and back translation, expert committee consolidation and pretesting among patients (n=10). Face and content validity were evaluated with a panel of experts (n=6) and group of patients (n=10). Confirmatory Factor Analysis (CFA) was performed to evaluate construct validity of two subscales of SINESRD-AQ. Subsequent Categorical Principal Component Analysis (CATPCA) was performed to identify a more parsimonious dimensionality to assess treatment adherence behaviors among patients. Ethical approval was obtained from the Ethics Review Committee, Faculty of Medical Sciences, University of Sri Jayewardenepura and Teaching Hospital, Kurunegala, Sri Lanka. ResultsA total of 150 patients with mean age of 54.08±10.78 (±SD) years were included. Majority were males (72.7%). Excellent face and content validity of SINESRD-AQ was reported. The CFA of two subscales of ESRD-AQ demonstrated barely acceptable model fit (SRMR=0.120, CFI=0.913, GFI=0.997, AGFI=0.996, NNFI=0.896). Subsequent CATPCA revealed new dimensionality with five components explaining 74% of the total variance. Convergent validity of new dimensionality was confirmed with Composite Reliability (CR) and Average Variance Extracted (AVE) with the values greater than 0.7 and 0.5 respectively. According to the Fornell Larcker criterion (1971), the square root of AVEs of components were greater than the inter component correlations and heterotrait-monotrait values were less than the threshold of 0.85 demonstrated the discriminant validity of new dimensionality.ConclusionSINESRD-AQ is a valid and a reliable instrument to assess treatment adherence behaviors among Sinhala speaking patients receiving haemodialysis in Sri Lanka. A follow-up CFA is to be performed to confirm the revised dimensionality of SINESRD-AQ.
Development and Validation of Multicenter Study on Novel Artificial Intelligence Based Cardiovascular Risk Score (AICVD)
Authors: Kumar Shiv , Gupta Prashant , Dekker Andre L.A.J. , Bermejo Inigo , Kar Sujoy 
Published: December 2021

Abstract
Cardiovascular diseases (CVD) are one of the most prevalent diseases in India amounting for nearly 30% of total deaths. A dearth of research on CVD risk scores in Indian population, limited performance of conventional risk scores and inability to reproduce the initial accuracies in randomized clinical trials – has led to this study on large-scale patient data. The objective is to develop an Artificial Intelligence based Risk Score (AICVD) to predict CVD Event (e.g. Acute MI / ACS) in next 10 years and compare the model with the Framingham Heart Risk Score (FHRS) and QRisk3.Our study included 31,599 participants aged 18-91 years from 2009 - 2018 in six Apollo Hospitals in India. A multi-step risk factors selection process using Spearman correlation coefficient and propensity score matching yielded 21 risk factors. A Deep Learning Hazard Model was built on risk factors to predict event occurrence (classification) and time to event (hazard model) using multi-layered neural network. Further, the model was validated with independent retrospective cohorts of participants from India and the Netherlands and compared with FHRS and QRisk3.The Deep Learning Hazard model had a good performance (AUC 0.853). Validation and comparative results showed AUCs between 0.84 to 0.92 with better Positive Likelihood Ratio (AICVD-6.16 to FHRS–2.24 and QRisk3–1.16) and Accuracy (AICVD– 80.15% to FHRS 59.71% and QRisk3 51.57%). In the Netherlands cohort, AICVD also outperformed the Framingham Heart Risk Model (AUC - 0.737 vs 0.707).This study concludes that the novel AI based CVD risk score has a higher predictive performance for cardiac events than conventional risk scores.
Intraoperative Mild Hyperoxia May be Associated with Improved Survival After Off-Pump Coronary Artery Bypass Grafting: A Retrospective Observational Study
Authors: Ju Jae-Woo , Choe Hyun Woo , Bae Jinyoung , Lee Seohee , Cho Youn Joung , Nam Karam , Jeon Yunseok 
Published: December 2021

Abstract
Background: The effect of hyperoxia due to supplemental oxygen administration on postoperative outcomes in patients undergoing cardiac surgery remains unclear. This retrospective study aimed to evaluate the relationship between intraoperative oxygen tension and mortality after off-pump coronary artery bypass grafting (OPCAB).Methods: The study included adult patients who underwent isolated OPCAB between July 2010 and June 2020. Patients were categorised into three groups based on their intraoperative time-weighted average arterial oxygen partial pressure (PaO2): normoxia/near-normoxia (<150 mmHg), mild hyperoxia (150–250 mmHg), and severe hyperoxia (>250 mmHg). The risk of in-hospital mortality was compared using weighted logistic regression analysis. Restricted cubic spline analysis was performed to analyse intraoperative PaO2 as a continuous variable. The risk of cumulative all-cause mortality was compared using Cox regression analysis.Results: The normoxia/near-normoxia, mild hyperoxia, and severe hyperoxia groups included 229, 991, and 173 patients (n=1,393), respectively. The mild hyperoxia group had a significantly lower risk of in-hospital mortality than the normoxia/near-normoxia (odds ratio [OR], 0.12; 95% confidence interval [CI], 0.06–0.22) and severe hyperoxia groups (OR, 0.06; 95% CI, 0.03–0.14). Intraoperative PaO2 exhibited a U-shaped relationship with in-hospital mortality in the non-hypoxic range. The risk of cumulative all-cause mortality was significantly lower in the mild hyperoxia group (hazard ratio, 0.72; 95% CI, 0.52–0.99) than in the normoxia/near-normoxia group.Conclusions: Intraoperative mild hyperoxia was associated with a lower risk of mortality after OPCAB than normoxia, near-normoxia, or severe hyperoxia. Mildly increasing arterial oxygen tension during OPCAB may help to optimise postoperative outcomes.Trial registration: Not applicable.