bluuebunny/crossref_metadata_2025_split huggingface dataset:
Economic Impact and Feasibility of Striped Catfish Farming (Pangasius hypophthalmus) in Mexico
Authors: Platas-Rosado Diego Esteban , González-Reynoso Luis , Hernández-Arzaba Juan Cristobal , Torres-Tadeo Cesar Mauricio 
Published: May 2021

Objective: To assess the productive behavior of Pangasius hypophthalmus in actual rural aquaculture farming conditions for the state of Veracruz, Mexico.
Methodology: The study had a duration of 331 days in a circular pond of 135 m3, with no aeration. 2000 juveniles were bred upon attaining 7.9 g; they were fed once a day, four days a week. Their weight and length were assessed every 15 days.
Results: The growth of P. hypophthalmus reached 900 g in 150 days at temperatures between 26 y 34 °C, with growths of 100 g in 150 days at temperatures between 22 and 26 °C. An average final weight of 1254 kg and a survival of 87.8% were attained for a total production of 2.2 t. These organisms may attain 2 kg per year at 26 to 35 °C-1.
Study limitations: For a period of 153 days, water temperatures greater than 26°C limited the growth of this fish.
Conclusions: The Pangasius hypophthalmus species represents an aquaculture alternative with high potential for tropical areas of Mexico, mainly where electric power availability is limited.
Editorial
Authors: Rocha-de-Oliveira Sidinei 
Published: May 2021

Nosso primeiro número de 2015 traz os Planos de Empreendimentos elaborados por alunos das turmas do Rio de Janeiro e São Paulo do curso de MBA em Gestão Empreendedora do ano de 2014. Desta forma, continuamos com o estímulo às publicações na linha de Educação e Empreendedorismo.Nesta edição, os planos contemplam diferentes áreas do ensino, com propostas para transformar a realidade escolar.O primeiro projeto Alimentação Saudável e transdisciplinaridade: possibilidades e desafios de Ricardo Antonio de Barros, se propõe a trabalhar a inter e transdisciplinaridade a partir da implementação do cultivo de legumes e hortaliças e o estímulo aos alunos para que tenham uma alimentação saudável e um maior envolvimento com a escola Escola SESI “José Pilon”, em Cerquilio/SP.No projeto Reforço Escolar, o segundo projeto desta edição, Nelson Petz Junior desenvolve um mecanismo de apoio escolar aos alunos da Escola Estadual Albino Fiore, localizada em Caieiras/ SP, a partir da utilização de espaços ociosos e do trabalho no contra turno, aplicando diferentes metodologias de ensino e minimizando as principais dificuldades dos alunos.No terceiro trabalho, Tania Cruxatti de Lima, da Escola Estadual Parque Macaraja II (Santo André – SP) busca avançar no ensino de matemática para o Ensino Fundamental, diagnosticado com baixo desempenho e estabilização nas avaliações. Dessa forma, o projeto AVA – Matemática se propõe a melhorar o processo de ensino-aprendizagem e motivar os alunos a ultrapassarem suas potencialidadesO quarto trabalho é de Fernanda Machado Pontes da Escola Estadual Zuleika Rapôso Valladares (Niterói – RJ). Intitulado Labótica Pedagógica o projeto foi desenvolvido para a implantação um laboratório de Matemática/Física/Robótica, onde serão realizados minicursos, empréstimos de materiais e atendimento a alunos e professores, com o objetivo de recuperar e oferecer reforço para a disciplina de Matemática das turmas de 7os e 9os anos,O quinto Plano de Empreendimento, Cursinho Pré-Vestibular Alexandre von Humboldt, de Maria de Fátima Braz Aragão Rizzo, tem como objetivo criar um momento de reflexão e diagnóstico para a Escola Estadual Alexandre von Humboldt (São Paulo/SP), como também estimular e preparar seus alunos para uma carreira e ingresso na universidade.Encerrando o nosso número, o sexto projeto, O mundo do mel, de Maria Cássia Sobreiro Dias Caldas, tem como objetivo melhorar o desempenho de seus estudantes em Português e Redação a partir da interdisciplinaridade dessas disciplinas com as Artes e a criação de um livro. O projeto será desenvolvido no âmbito da Escola SESI de São João da Boa Vista(São Paulo). Boa Leitura!
The Future is Here: Library Services for Mobile Devices
Authors: Wilson Sally 
Published: May 2021

<p>"What does your library website look like on a cell phone? What library services do your patrons want to access on a mobile device? The first question is easily answered. Unless your patron is using an iPhone or iPod Touch, your library website as viewed on their phone will have little resemblance to the carefully crafted site that displays on a laptop or desktop computer. The answer to the second question will depend very much on the types of users that frequent your library."</p>
Comparison of Internal Forces Redistribution and Displacements Subjected to the Dynamic Wind Gusts depending of Point Fixed Glass Connector Model Shape
Authors: Kuliński Krzysztof , Palacz Przemysław 
Published: May 2021

This paper presents an analysis of the redistribution of stresses and displacements in numerical models of various shapes of glass connectors. Two states of dynamic wind gusts were analyzed: the maximum value of suction and the maximum value of wind pressure. For the sake of simplicity, wind gusts were assumed periodically as a sinusoidal function. The model adopts a rectangular glass plate that transmits wind pressure and suction through the point fixed glass connectors. Therefore, single-arm cross connectors were not only subjected to bending stress, but also to torsion. Four different shapes of connectors were analyzed. In the first part of the numerical analysis, T-shaped and C-shaped cross-sections were adopted, and in the next part, both connectors were modified by adding fillet welds to the models. The dynamic numerical analysis was performed using the finite element method in the ADINA program.
Racial and socioeconomic disparities in lung cancer screening in the United States: A systematic review
Authors: Sosa Ernesto , D’Souza Gail , Akhtar Aamna , Sur Melissa , Love Kyra , Duffels Jeanette , Raz Dan J. , Kim Jae Y. , Sun Virginia , Erhunmwunsee Loretta 
Published: May 2021

AbstractNonsmall cell lung cancer (NSCLC) is the leading cause of cancer deaths. Lung cancer screening (LCS) reduces NSCLC mortality; however, a lack of diversity in LCS studies may limit the generalizability of the results to marginalized groups who face higher risk for and worse outcomes from NSCLC. Identifying sources of inequity in the LCS pipeline is essential to reduce disparities in NSCLC outcomes. The authors searched 3 major databases for studies published from January 1, 2010 to February 27, 2020 that met the following criteria: 1) included screenees between ages 45 and 80 years who were current or former smokers, 2) written in English, 3) conducted in the United States, and 4) discussed socioeconomic and race‐based LCS outcomes. Eligible studies were assessed for risk of bias. Of 3721 studies screened, 21 were eligible. Eligible studies were evaluated, and their findings were categorized into 3 themes related to LCS disparities faced by Black and socioeconomically disadvantaged individuals: 1) eligibility; 2) utilization, perception, and utility; and 3) postscreening behavior and care. Disparities in LCS exist along racial and socioeconomic lines. There are several steps along the LCS pipeline in which Black and socioeconomically disadvantaged individuals miss the potential benefits of LCS, resulting in increased mortality. This study identified potential sources of inequity that require further investigation. The authors recommend the implementation of prospective trials that evaluate eligibility criteria for underserved groups and the creation of interventions focused on improving utilization and follow‐up care to decrease LCS disparities.
Aplicación de medidas de seguridad y bioseguridad en empresas comerciales del cantón Machala
Authors: Aguilar-Cerón Priscilla , Luzardo-Lambert Ingeborth , Romero-Black Wilton , Jaya-Pineda Iddar 
Published: May 2021

El Corona Virus Disease 2019 o más conocido como Covid-19 es provocado por el nuevo coronavirus llamado SARS-CoV-2, este virus ha cambiado el estilo de vida y de sanidad de todas las personas en el mundo, incluyendo a los comerciantes, que son aquellos que tiene un mayor contacto directo con los ciudadanos, es por tal razón que el presente proyecto pretende conocer sobre las medidas de seguridad y de Bioseguridad que se aplican en las diversas empresas comerciales del cantón Machala, para ello se realiza una profunda investigación bibliográfica en donde se consideran las medidas de prevención que ofrece el Gobierno Nacional, El ministerio de salud, La OMS, y más, con el fin de conocer cuáles son las que se aplican desde el inicio de la cuarentena hasta la actualidad. Para ello se realiza una investigación Cuali-cuantitativa, es decir que a más de realizar la investigación bibliográfica también se considera la información obtenida por una encuesta, en línea, que fue aplicada a los gerentes o dueños de los locales comerciales de los 3 principales centros comerciales de la ciudad de Machala, presentando como resultado una importancia regular, de los mismos, ante las medidas de protección, debido a que ellos hacen uso de ciertas medidas de bioseguridad y seguridad, siendo estas disminuidas desde el inicio de la cuarentena hasta la actualidad, a más de que aún existen falencias como la suspensión del uso de señalética, un plan de contingencia, capacitaciones a los empleados, entre otro.
Dynamic Observation of the Effect of Maternal Caries on the Oral Microbiota of Infants Aged 12–24 Months
Authors: Li Fei , Fu Ding , Tao Danying , Feng Xiping , Wong May Chun Mei , Xu Wei , Lu Haixia 
Published: May 2021

AimTo provide a dynamic description of the oral microbial composition in mothers with and without dental caries and their children aging 12-24 months.MethodologyA total of 20 pairs of mothers and their children aged 12 months were included and followed up at 18 and 24 months of age. Ten mothers with dental caries(MEG) and their children(CEG) were in the exposure group, and ten caries-free mothers(MCG) and their children(CCG)in control group. Supragingival plaque biofilm samples were collected and DNA was extracted for bacterial 16S rRNA gene sequencing.ResultsA total of 18 pairs completed follow-ups. At a 3% divergence level, the number of common operational taxonomic units found between the mothers and children increased as the children aged. Proteobacteria, Bacteroidetes, Firmicutes, Fusobacteria, and Actinobacteria accounted for more than 80% phyla of each group. A microbial community structure analysis showed that the differences between mothers and children were significant in all groups except for the MEG24 and CEG24 groups.ConclusionsOral microbiota of children was more like their mothers’ with increasing age, regardless of whether the mothers had dental caries. Mothers with dental caries may have a greater influence on the oral microbiota of children’s than those without dental caries as children age.
Geochronology and Geochemistry of Late Paleozoic Volcanic Rocks and Their Relationship With Iron and Molybdenum Deposits in Xilekuduk Area, Northern Margin of Junggar
Authors: Wei Xiaofeng , Wei Hao , Liao Zhen , Wang Zhiwei , Li Dong , Mao Qigui , Li Xiao 
Published: May 2021

A large number of intermediate basic volcanic rocks and porphyry Cu-Mo deposits as well as volcanic-hosted magnetite deposit have been recently discovered in the Xilekuduk area. However, no reports concerning petrogenesis and age or their relationship with mineralization have been published to date. The purpose of this study was to make up for the absence of previous studies on Devonian volcanic activities in the area and to confirm the relationship between two stages of volcanic activities and mineralization so as to provide important theoretical basis for mineral exploration. Based on research results of zircon U-Pb geochronology and element geochemistry of volcanic rocks in the area, the ages of dacite, andesite, and stomatal andesite are considered as 375.2 ± 2.9 Ma, 386.5 ± 3.0 Ma, and 317.9 ± 2.9 Ma, respectively, corresponding to the Middle Devonian and Late Carboniferous Period. The Devonian volcanic rocks belong to the high-K calc-alkaline series and island arc volcanic rocks, which are enriched in LREE, strongly enriched in large ion lithophile elements Th, Rb, Ba, and K and relatively depleted in high-field strength elements (HFSEs) Nb, Ta, and Ti. The Carboniferous volcanic rocks are enriched in LREE, as well as the large ion lithophile elements Th, Rb, Ba, and K are strongly enriched, while depleted in the HFSEs Nb, Ta, and Ti; moreover, the contents of TiO2and V are 0.94–0.97% and 178–183×10–6, which are higher than those of island arc basalts. According to mineralogical typomorphic characteristics and geochemical analysis, magnetite mineralization is divided into two phases. The early stratiform magnetite ore MT1 has magmatic characteristics, forming a volcanic rock type magnetite deposit related to Devonian volcanic eruption and sedimentation (375–386 Ma). The magnetite MT2 in the magnetite-quartz vein is considered as hydrothermal genesis, which is a metal mineral in the early metallogenic stage of Carboniferous (317.1 ± 2.9 Ma) volcanic eruption and subvolcanism, and may be related to porphyry molybdenum mineralization. Therefore, the volcanism and Fe-Cu-Mo mineralization in this area is characterized by multistage superimposed mineralization.
Safranal Alleviated OVA-Induced Asthma Model and Inhibits Mast Cell Activation
Authors: Lertnimitphun Peeraphong , Zhang Wenhui , Fu Wenwei , Yang Baican , Zheng Changwu , Yuan Man , Zhou Hua , Zhang Xue , Pei Weizhong , Lu Yue , Xu Hongxi 
Published: May 2021

IntroductionAsthma is a chronic and recurring airway disease, which related to mast cell activation. Many compounds derived from Chinese herbal medicine has promising effects on stabilizing mast cells and decreasing inflammatory mediator production. Safranal, one of the active compounds from Crocus sativus, shows many anti-inflammatory properties. In this study, we evaluated the effect of safranal in ovalbumin (OVA)-induced asthma model. Furthermore, we investigate the effectiveness of safranal on stabilizing mast cell and inhibiting the production of inflammatory mediators in passive systemic anaphylaxis (PSA) model.MethodsOVA-induced asthma and PSA model were used to evaluate the effect of safranal in vivo. Lung tissues were collected for H&amp;E, TB, IHC, and PAS staining. ELISA were used to determine level of IgE and chemokines (IL-4, IL-5, TNF-α, and IFN-γ). RNA sequencing was used to uncovers genes that safranal regulate. Bone marrow-derived mast cells (BMMCs) were used to investigate the inhibitory effect and mechanism of safranal. Cytokine production (IL-6, TNF-α, and LTC4) and NF-κB and MAPKs signaling pathway were assessed.ResultsSafranal reduced the level of serum IgE, the number of mast cells in lung tissue were decreased and Th1/Th2 cytokine levels were normalized in OVA-induced asthma model. Furthermore, safranal inhibited BMMCs degranulation and inhibited the production of LTC4, IL-6, and TNF-α. Safranal inhibits NF-κB and MAPKs pathway protein phosphorylation and decreases NF-κB p65, AP-1 nuclear translocation. In the PSA model, safranal reduced the levels of histamine and LTC4 in serum.ConclusionsSafranal alleviates OVA-induced asthma, inhibits mast cell activation and PSA reaction. The possible mechanism occurs through the inhibition of the MAPKs and NF-κB pathways.
Development of a Machine Learning-Based Autophagy-Related lncRNA Signature to Improve Prognosis Prediction in Osteosarcoma Patients
Authors: Zhang Guang-Zhi , Wu Zuo-Long , Li Chun-Ying , Ren En-Hui , Yuan Wen-Hua , Deng Ya-Jun , Xie Qi-Qi 
Published: May 2021

BackgroundOsteosarcoma is a frequent bone malignancy in children and young adults. Despite the availability of some prognostic biomarkers, most of them fail to accurately predict prognosis in osteosarcoma patients. In this study, we used bioinformatics tools and machine learning algorithms to establish an autophagy-related long non-coding RNA (lncRNA) signature to predict the prognosis of osteosarcoma patients.MethodsWe obtained expression and clinical data from osteosarcoma patients in the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) and Gene Expression Omnibus (GEO) databases. We acquired an autophagy gene list from the Human Autophagy Database (HADb) and identified autophagy-related lncRNAs by co-expression analyses. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses of the autophagy-related lncRNAs were conducted. Univariate and multivariate Cox regression analyses were performed to assess the prognostic value of the autophagy-related lncRNA signature and validate the relationship between the signature and osteosarcoma patient survival in an independent cohort. We also investigated the relationship between the signature and immune cell infiltration.ResultsWe initially identified 69 autophagy-related lncRNAs, 13 of which were significant predictors of overall survival in osteosarcoma patients. Kaplan-Meier analyses revealed that the 13 autophagy-related lncRNAs could stratify patients based on their outcomes. Receiver operating characteristic curve analyses confirmed the superior prognostic value of the lncRNA signature compared to clinically used prognostic biomarkers. Importantly, the autophagy-related lncRNA signature predicted patient prognosis independently of clinicopathological characteristics. Furthermore, we found that the expression levels of the autophagy-related lncRNA signature were significantly associated with the infiltration levels of different immune cell subsets, including T cells, NK cells, and dendritic cells.ConclusionThe autophagy-related lncRNA signature established here is an independent and robust predictor of osteosarcoma patient survival. Our findings also suggest that the expression of these 13 autophagy-related lncRNAs may promote osteosarcoma progression by regulating immune cell infiltration in the tumor microenvironment.
Patients With Becker Muscular Dystrophy Have Severe Paraspinal Muscle Involvement
Authors: Sheikh Aisha M. , Rudolf Karen , de Stricker Borch Josefine , Khawajazada Tahmina , Witting Nanna , Vissing John 
Published: May 2021

Introduction: Paraspinal muscles are important for gross motor functions. Impairment of these muscles can lead to poor postural control and ambulation difficulty. Little knowledge exists about the involvement of paraspinal muscles in Becker muscular dystrophy.Objective: In this cross-sectional study, we investigated the involvement of paraspinal muscles with quantitative trunk strength measure and quantitative muscle MRI.Methods and Materials: Eighteen patients with Becker muscular dystrophy underwent trunk, hip, and thigh strength assessment using a Biodex dynamometer and an MRI Dixon scan. Fourteen age- and body mass index-matched healthy men were included for comparison.Results: Muscle fat fraction (FF) of the paraspinal muscles (multifidus and erector spinae) was higher in participants with Becker muscular dystrophy vs. healthy controls at all three examined spinal levels (C6, Th12, and L4/L5) (p &lt; 0.05). There was a strong and inverse correlation between paraspinal muscle FF and trunk extension strength (ρ = −0.829, p &lt; 0.001), gluteus maximus FF and hip extension strength (ρ = −0.701, p = 0.005), FF of the knee extensor muscles (quadriceps and sartorius) and knee extension strength (ρ = −0.842, p &lt; 0.001), and FF of the knee flexor muscles (hamstring muscles) and knee flexion strength (ρ = −0.864, p &lt; 0.001). Fat fraction of the paraspinal muscles also correlated with muscle FF of the thigh muscles and lower leg muscles.Conclusion: In conclusion, patients with Becker muscular dystrophy demonstrate severe paraspinal muscular involvement indicated by low back extension strength and high levels of fat replacement, which parallel involvement of lower limb muscles. Assessment of paraspinal muscle strength and fat replacement may serve as a possible biomarker for both the clinical management and further study of the disease.
Feature Counting Is Impaired When Shifting Attention Between the Eyes in Adults With Amblyopia
Authors: Hou Chuan , Acevedo Munares Gabriela 
Published: May 2021

BackgroundFeature counting requires rapid shifts of attention in the visual field and reflects higher-level cortical functions. This process is drastically impaired in the amblyopic eye of strabismic amblyopes. In this study, we hypothesized that feature counting performance in anisometropic and strabismic amblyopes is further impaired when shifts in attention is required between the eyes.Materials and MethodsThrough a mirror stereoscope, highly visible Gabor patches were presented to the same eye within a block or randomly presented to the left eye or to the right eye with an equal probability within a block. The task was to report the number of Gabors (3 to 9) as accurately as possible. Counting performance was compared between the amblyopes and the normal-vision observers and between the viewing conditions (shifting attention between the eyes versus maintaining attention in the same eye).ResultsWhen attention was maintained in the same eye, the amblyopic eye of both anisometropic and strabismic groups undercounted the number of Gabors, but achieved near-perfect performance with their fellow eye, compared to normal-vision observers. In contrast, when shifting attention randomly to the left or to the right eye, the amblyopic eye further undercounted the number of Gabors. Undercounting was also found in the fellow eye of strabismic amblyopes, but was not in the fellow eye of anisometropic amblyopes. Performance in normal-vision observers did not differ between shifting attention between the eyes and maintaining attention in the same eye.ConclusionOur data showed that the amblyopic eye of both anisometropic and strabismic amblyopes further undercounted features when shifting attention between the eyes, compared to when maintaining attention in the same eye. This suggests that the ability to quickly redirect attention, particularly under interocular suppression, is impaired in amblyopia. The fellow eye of strabismic amblyopes also undercounted features when shifting attention between the eyes. However, such fellow eye abnormality was not found in anisometropic amblyopes, suggesting that different patterns of visual deficits are associated with amblyopia of different etiologies. The inability to count multiple features accurately reflects dysfunctions of high-level cortices in the amblyopic brain.