bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beneficial effects of empagliflozin on hematocrit levels in a patient with severe anemia
Authors: Budzianowski Jan , Rzeźniczak Janusz , Hiczkiewicz Jarosław , Kasprzak Dominika , Winnicka-Zielińska Anna , Musielak Bogdan , Pieszko Konrad , Burchardt Paweł 
Published: September 2021

Abstract
Introduction
Sodium-glucose cotransporter (SGLT2) inhibitors may additionally benefit patients with diabetes by improving their erythropoiesis followed by the elevation of hemoglobin and hematocrit levels.

Reason for the report
In the case described, severe normocytic normochromic anemia was resolved when empagliflozin had been introduced to the therapy.

Case summary
A 78-year-old male patient was admitted to our hospital with a non-ST-segment elevation myocardial infarction. His past medical history included diabetes, right coronary artery angioplasty, myocardial infarction and paroxysmal atrial fibrillation which required anticoagulant treatment. When examined, severe normocytic normochromic anemia was also diagnosed. About two years prior to his admission, the patient began suffering from persistent anemia despite the modification of his anticoagulant therapy with warfarin, rivaroxaban and dabigatran. An extensive evaluation failed to provide an explanation for his anemia.

Outcome
Eventually, only the introduction of empagliflozin successfully increased the values of hemoglobin and hematocrit. Therefore, it transpires that SGLT2 enhances erythropoietin (EPO) secretion which subsequently raises hematocrit levels in patients with severe anemia.

Graphic abstract
Accelerating privacy-preserving momentum federated learning for industrial cyber-physical systems
Authors: Zhang Linlin , Zhang Zehui , Guan Cong 
Published: September 2021

AbstractFederated learning (FL) is a distributed learning approach, which allows the distributed computing nodes to collaboratively develop a global model while keeping their data locally. However, the issues of privacy-preserving and performance improvement hinder the applications of the FL in the industrial cyber-physical systems (ICPSs). In this work, we propose a privacy-preserving momentum FL approach, named PMFL, which uses the momentum term to accelerate the model convergence rate during the training process. Furthermore, a fully homomorphic encryption scheme CKKS is adopted to encrypt the gradient parameters of the industrial agents’ models for preserving their local privacy information. In particular, the cloud server calculates the global encrypted momentum term by utilizing the encrypted gradients based on the momentum gradient descent optimization algorithm (MGD). The performance of the proposed PMFL is evaluated on two common deep learning datasets, i.e., MNIST and Fashion-MNIST. Theoretical analysis and experiment results confirm that the proposed approach can improve the convergence rate while preserving the privacy information of the industrial agents.
Tip-Based Nanomachining on Thin Films: A Mini Review
Authors: Chang Shunyu , Geng Yanquan , Yan Yongda 
Published: September 2021

AbstractAs one of the most widely used nanofabrication methods, the atomic force microscopy (AFM) tip-based nanomachining technique offers important advantages, including nanoscale manipulation accuracy, low maintenance cost, and flexible experimental operation. This technique has been applied to one-, two-, and even three-dimensional nanomachining patterns on thin films made of polymers, metals, and two-dimensional materials. These structures are widely used in the fields of nanooptics, nanoelectronics, data storage, super lubrication, and so forth. Moreover, they are believed to have a wide application in other fields, and their possible industrialization may be realized in the future. In this work, the current state of the research into the use of the AFM tip-based nanomachining method in thin-film machining is presented. First, the state of the structures machined on thin films is reviewed according to the type of thin-film materials (i.e., polymers, metals, and two-dimensional materials). Second, the related applications of tip-based nanomachining to film machining are presented. Finally, the current situation of this area and its potential development direction are discussed. This review is expected to enrich the understanding of the research status of the use of the tip-based nanomachining method in thin-film machining and ultimately broaden its application.
The Occupational Health Effects of Responding to a Natural Gas Pipeline Explosion Among Emergency First Responders – Lincoln County, Kentucky, 2019
Authors: Bui David P. , Kukielka Esther A. , Blau Erin F. , Tompkins Lindsay K. , Bing K. Leann , Edge Charles , Hardin Rebecca , Miller Diane , House James , Boehmer Tegan , Winquist Andrea , Orr Maureen , Funk Renée , Thoroughman Doug 
Published: September 2021

AbstractObjective:The aim of the study was to assess occupational health effects 1 month after responding to a natural gas pipeline explosion.Methods:First responders to a pipeline explosion in Kentucky were interviewed about pre- and post-response health symptoms, post-response health care, and physical exertion and personal protective equipment (PPE) use during the response. Logistic regression was used to examine associations between several risk factors and development of post-response symptoms.Results:Among 173 first responders involved, 105 (firefighters [58%], emergency medical services [19%], law enforcement [10%], and others [12%]) were interviewed. Half (53%) reported at least 1 new or worsening symptom, including upper respiratory symptoms (39%), headache (18%), eye irritation (17%), and lower respiratory symptoms (16%). The majority (79%) of symptomatic responders did not seek post-response care. Compared with light-exertion responders, hard-exertion responders (48%) had significantly greater odds of upper respiratory symptoms (aOR: 2.99, 95% CI: 1.25–7.50). Forty-four percent of responders and 77% of non-firefighter responders reported not using any PPE.Conclusions:Upper respiratory symptoms were common among first responders of a natural gas pipeline explosion and associated with hard-exertion activity. Emergency managers should ensure responders are trained in, equipped with, and properly use PPE during these incidents and encourage responders to seek post-response health care when needed.
An evaluation of sustainability and societal impact of high-power laser and fusion technologies: a case for a new European research infrastructure
Authors: Atzeni S. , Batani D. , Danson C. N. , Gizzi L. A. , Perlado M. , Tatarakis M. , Tikhonchuk V. , Volpe L. 
Published: September 2021

Abstract
Fusion energy research is delivering impressive new results emerging from different infrastructures and industrial devices evolving rapidly from ideas to proof-of-principle demonstration and aiming at the conceptual design of reactors for the production of electricity. A major milestone has recently been announced in laser fusion by the Lawrence Livermore National Laboratory and is giving new thrust to laser-fusion energy research worldwide. Here we discuss how these circumstances strongly suggest the need for a European intermediate-energy facility dedicated to the physics and technology of laser-fusion ignition, the physics of fusion materials and advanced technologies for high-repetition-rate, high-average-power broadband lasers. We believe that the participation of the broader scientific community and the increased engagement of industry, in partnership with research and academic institutions, make most timely the construction of this infrastructure of extreme scientific attractiveness.
Pretty (and) invasive: The potential global distribution of Tithonia diversifolia under current and future climates
Authors: Kriticos Jessica M. , Kriticos Darren J. 
Published: September 2021

AbstractMexican sunflower [Tithonia diversifolia (Hemsl.) A. Gray] is an invasive plant, native to the New World, and an exemplary conflict species. It has been planted widely for its ornamental and soil fertility enhancement qualities and has become a notorious environmental weed in introduced habitats. Here we use a bioclimatic niche model (CLIMEX) to estimate the potential global distribution of this invasive plant under historical climatic conditions. We apply a future climate scenario to the model to assess the sensitivity of the modeled potential geographic range to expected climate changes to 2050. Under current climatic conditions, there is potential for substantial range expansion into southern Europe with moderate climate suitability, and in southern China with highly suitable climates. Under the near-term future climate scenario, there is potential for poleward range expansion in the order of 200 to 500 km. In the tropics, climatic conditions are likely to become less favorable due to the increasing frequency of supra-optimal temperatures. In areas experiencing Mediterranean or warm temperate climates, the suitability for T. diversifolia appears set to increase as temperatures warm. There are vast areas in North America, Europe, and Asia (particularly China and India) that can support ephemeral populations of T. diversifolia. One means of enjoying the aesthetic benefits of T. diversifolia in gardens while avoiding the unwanted environmental impacts where it invades is to prevent its spread into areas climatically suitable for establishment and only allow it to be propagated in areas where it cannot persist naturally.
Digital transformation: a conceptual framing for attaining Sustainable Development Goals 4 and 9 in Nigeria
Authors: Ufua Daniel E. , Emielu Emmanuel T. , Olujobi Olusola J. , Lakhani Faraz , Borishade Taiye T. , Ibidunni Ayodotun S. , Osabuohien Evans S. 
Published: September 2021

AbstractThis study explores the potentials of digital transformation for achieving the United Nations Sustainable Development Goals (SDGs), with emphasis on SDG 4 and SDG 9 in Nigeria. The study adopts a conceptual approach, reviewing existing literature to explore the topic from various views of authors on the issue. It focuses on the contextual factors such as stakeholder input to the process of the implementation of digitalisation and SDGs 4 and 9 which focuses on educational development at all levels, industrial collaborations and improvements, respectively. The results indicate that digital transformation potentially enhances the attainment of SDGs 4 and 9, but this is mediated by the level of stakeholder commitment and e-governance performance. Part of the recommendation is the adoption of a multi-disciplinary approach to development-oriented digital transformation interventions for SDGs 4 and 9 in Nigeria, through a process of effective stakeholder engagement and transparent institutional signalling. The study draws research attention to the use of digital transformation for social development, especially in a developing economy such as Nigeria, to enhance the compendium of knowledge in the implementation of digital approach to the attainment of SDGs 4 and 9. It is also suggested for the government institutions to take further responsibility to provide a fair platform for the implementation of digital transformation and the attainment of SDGs 4 and 9 in Nigeria.
Entrepreneurship and the Post-COVID-19 Recovery in Emerging Economies
Authors: Meyer Klaus E. , Prashantham Shameen , Xu Shiqi 
Published: September 2021

ABSTRACTEntrepreneurs play a focal role in a society's economic recovery from major disruptions such as the COVID-19 pandemic. We argue that entrepreneurs’ ability to identify and act on entrepreneurial opportunities during the crisis reflects their resilience, and their innovations facilitate new patterns of work, learning, and leisure activities in post-COVID-19 societies. However, how, how quickly they act, and how influential their actions are depends on their context in terms of institutions, resource access, and market volatility. In China, some entrepreneurs have shown great resilience by utilizing network relationships and digital technology, not only to overcome short-term disruptions in 2020 but to shape the evolving ‘new normal’ where behaviors and capabilities have changed as a consequence of the experience of the pandemic. We discuss drivers of such resilient entrepreneurship during the COVID-19 pandemic in China and call for further research on the interplay between external disruptions, different types of entrepreneurship, and the consequences for resilience in emerging economies.
Strategic Configurations and International Performance of Emerging Economy Multinationals
Authors: Li Yi , Cui Lin , Meyer Klaus E. , Fan Di 
Published: September 2021

ABSTRACTThis study examines the international performance of emerging economy multinational enterprises (EMNEs) from a strategic configuration perspective. We propose that the strategic patterns of EMNEs that deliver growth and/or profitability are characterized by different configurations of environment, strategy, and managerial resource factors. Therefore, identifying and assessing strategic configurations is key to understanding EMNEs’ international performance. Employing fuzzy-set qualitative comparative analysis, we analyze a multi-sourced dataset of Chinese firms’ outward investment and identify multiple equifinal strategic configurations that are associated with superior international performance in terms of sales growth and/or profitability. These findings inform the development of a taxonomy of EMNEs’ strategic configurations corresponding with three performance groups, namely profitable growth, profitable niche, and poor performers.
Can a beautiful smile win the vote?
Authors: Masch Lena , Gassner Anna , Rosar Ulrich 
Published: September 2021

AbstractSeveral empirical studies have linked political candidates’ electoral success to their physical appearance. We reexamine the effects of candidates’ physical attractiveness by taking into account emotional facial expressions as measured by automated facial recognition software. The analysis is based on an observational case study of candidate characteristics in the 2017 German federal election. Using hierarchical regression modeling and controlling for candidates’ displays of happiness, consistent effects of physical attractiveness remain. The results suggest that a potential interaction effect between displays of happiness and attractiveness positively affects vote shares. The study emphasizes the importance of considering emotional expressions when analyzing the impact of candidate appearance on electoral outcomes.
Using cover crops to offset greenhouse gas emissions from a tropical soil under no-till
Authors: Rigon João Paulo Gonsiorkiewicz , Calonego Juliano Carlos , Pivetta Laércio Augusto , Castoldi Gustavo , Raphael Juan Piero Antonio , Rosolem Ciro Antônio 
Published: September 2021

AbstractCrop rotations under no-till (NT) have been a strategy to increase soil organic carbon (SOC) and mitigate greenhouse gas (GHG) emissions, enhancing the cropping system efficiency. However, there is still controversy on the role of grasses and legumes, and species diversity and their impacts. This study aimed to assess the GHG emissions, SOC, and Nitrogen (TN) in a soybean production system managed under NT in rotation with different species in the fall–winter and the spring seasons. Main plots during the fall–winter were (1) Triticale (x Triticosecale) and (2) Sunflower (Helianthus annuus). Subplots established in the spring were (a) Sunn hemp (Crotalaria juncea), (b) Sorghum (Sorghum bicolor), (c) Pearl millet (Pennisetum glaucum), plus a (d) Fallow treatment. Soybean was grown every year in the summer, in sub-subplots. The GHG emission was affected according to crop species. In the spring, Sunn hemp emitted more nitrous oxide (N2O) (0.82 kg ha−1) than fallow (0.58 kg ha−1); however, the high C and N inputs by the legume and also other cover crop residues reduced the relative emissions compared with fallow. Growing pearl millet or Sunn hemp as a spring cover crop increases SOC by 7% on average compared with fallow. The N2O emission of Sunn hemp accounted for only 0.28% of the total N accumulated in the legume residues, notably lower than IPCC estimates. In the fall–winter, Triticale increased SOC by 7%, decreased CO2 emission by 18%, and emitted 20% lower GHG to produce the same soybean yield compared with sunflower. Soybean rotation with triticale in fall–winter and Sunn hemp or pearl millet in spring decreases GHG emissions. Our results indicate that the right choice of species in rotation with soybean under NT increases SOC and may offset GHG emissions from tropical soils. It may be an important tool in mitigating potential global warming.
Fixed-time corrective dose fertilizer nitrogen management in wheat using atLeaf meter and leaf colour chart
Authors: Ali Ali M. , Ibrahim Sherif M. , Hassany Wahby M. , El-Sadek Ashraf N. , Bijay-Singh  
Published: September 2021

AbstractFertilizer nitrogen (N) management in any region following standard general recommendations discount the fact that crop response to N varies between sites and seasons. To devise field-specific N management in wheat at jointing stage (Feekes 6 growth stage) using atLeaf meter and leaf colour chart (LCC), eight field experiments were conducted in three wheat seasons during 2017–2020 in the West Delta of Egypt. In the first two seasons, four experiments consisted of treatments with a range of fertilizer N application levels from 0 to 320 kg N ha−1. Monitoring atLeaf and LCC measurements at Feekes 6 growth stage in plots with different yield potentials allowed formulation of different criteria to apply field-specific and crop need-based fertilizer N doses. In the four experiments conducted in the third season in 2019/20, different field-specific N management strategies formulated in 2017/18 and 2018/19 wheat seasons were evaluated. In the atLeaf-based fertilizer N management experiment, prescriptive application of 40 kg N ha−1at 10 days after seeding (DAS) and 60 kg N ha−1at 30 DAS followed by application of an adjustable dose at Feekes 6 stage computed by multiplying the difference of atLeaf measurements of the test plot and the N-sufficient plot with 42.25 (as derived from the functional model developed in this study), resulted in grain yield similar or higher to that obtained by following the standard treatment. The LCC-based strategy to apply field-specific fertilizer N at Feekes 6 stage consisted of applying 150, 100 or 0 kg N ha−1based on LCC shade equal to or less than 4, between 4 and 5 or equal to or more than 5, respectively. Both atLeaf- and LCC-based fertilizer N management strategies not only recorded the highest grain yield levels but also resulted in higher use efficiency with 57–60 kg N ha−1in average less fertilizer use than the standard treatment.
Developmental milestones in early childhood and genetic liability to neurodevelopmental disorders
Authors: Hannigan Laurie J. , Askeland Ragna Bugge , Ask Helga , Tesli Martin , Corfield Elizabeth , Ayorech Ziada , Magnus Per , Njølstad Pål Rasmus , Øyen Anne-Siri , Stoltenberg Camilla , Andreassen Ole A. , Ronald Angelica , Smith George Davey , Reichborn-Kjennerud Ted , Havdahl Alexandra 
Published: September 2021

AbstractBackgroundTiming of developmental milestones, such as age at first walking, is associated with later diagnoses of neurodevelopmental disorders. However, its relationship to genetic risk for neurodevelopmental disorders in the general population is unknown. Here, we investigate associations between attainment of early-life language and motor development milestones and genetic liability to autism, attention deficit hyperactivity disorder (ADHD), and schizophrenia.MethodsWe use data from a genotyped sub-set (N = 25699) of children in the Norwegian Mother, Father and Child Cohort Study (MoBa). We calculate polygenic scores (PGS) for autism, ADHD, and schizophrenia and predict maternal reports of children's age at first walking, first words, and first sentences, motor delays (18 months), and language delays and a generalised measure of concerns about development (3 years). We use linear and probit regression models in a multi-group framework to test for sex differences.ResultsWe found that ADHD PGS were associated with earlier walking age (β = −0.033, padj < 0.001) in both males and females. Additionally, autism PGS were associated with later walking (β = 0.039, padj = 0.006) in females only. No robust associations were observed for schizophrenia PGS or between any neurodevelopmental PGS and measures of language developmental milestone attainment.ConclusionsGenetic liabilities for neurodevelopmental disorders show some specific associations with the age at which children first walk unsupported. Associations are small but robust and, in the case of autism PGS, differentiated by sex. These findings suggest that early-life motor developmental milestone attainment is associated with genetic liability to ADHD and autism in the general population.
Older people's lived experience and the World Health Organization age-friendly policy framework: a critical examination of an age-friendly county programme in Ireland
Authors: McDonald Bernard , Scharf Thomas , Walsh Kieran 
Published: September 2021

AbstractDeveloping age-friendly communities is a significant global policy issue. The World Health Organization's (WHO) age-friendly cities and communities initiative significantly influenced the development of Ireland's Age-friendly Programme. This article critically examines the utilisation of the WHO age-friendly planning framework in the context of Ireland. It explores older adults’ experience of living in a county which is currently implementing an age-friendly programme, and uses this analysis to assess how the age-friendly programme addresses older residents’ needs, and to illustrate how the WHO conceptual and planning framework has worked in Ireland. The article reports on a qualitative case study which used constructivist grounded theory to explore the lived experience of older adults. The research identifies salient social and cultural dimensions of the day-to-day lived experience of older people which, although they impact on the age-friendliness of the places in which they live, are downplayed or neglected in the WHO framework. In critically analysing the transfer and relevance of the WHO age-friendly model in light of broader issues such as diversity of place, the dynamic nature of person–place relations, and the interplay between age-friendly policy and other age-related public policy, the article suggests ways in which the use of the WHO framework can be modified to accommodate better the diverse experience of older adults in Ireland, but also in other geographic and cultural contexts.
Design and development of a novel autonomous scaled multiwheeled vehicle
Authors: Tan Aaron Hao , Peiris Michael , El-Gindy Moustafa , Lang Haoxiang 
Published: September 2021

AbstractThis article proposes the design and development of a novel custom-built, autonomous scaled multiwheeled vehicle that features an eight-wheel drive and eight-wheel steer system. In addition to the mechanical and electrical design, high-level path planning and low-level vehicle control algorithms are developed and implemented including a two-stage autonomous parking algorithm is developed. A modified position-based visual servoing algorithm is proposed and developed to achieve precise pose correction. The results show significant gains in accuracy and efficiency comparing with an open-source path planner. It is the aim of this work to expand the research of autonomous platforms taking the form of commercial and off-road vehicles using actuated steering and other mechanisms attributed to passenger vehicles. The outcome of this work is a unique autonomous research platform that features independently driven wheels, steering, autonomous navigation, and parking.