bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Rasio Likuiditas dan Rasio Profitabilitas terhadap Harga Saham Pada Perusahaan Indeks IDX-30
Authors: Husain Fauziah 
Published: April 2021

Tujuan dari penelitian ini adalah untuk mengetahui bagaimana rasio likuiditas dan profitabilitas secara simultan maupun secara parsial akan mempengaruhi harga saham perusahaan Indeks IDX-30 periode 2018-2019. Metode penelitian yang digunakan adalah metode explanatory. Populasi dalam penelitian ini adalah perusahaan Indeks IDX-30 periode 2018-2019 yang berjumlah 30 perusahaan. Teknik pengambilan sampel menggunakan non probability sampling dengan metode purposive sampling, sehingga sampel penelitian ini sebanyak 25 perusahaan. Metode analisis data yang digunakan adalah analisis regresi linear berganda dengan pengujian hipotesis menggunakan uji F dan Uji t yang terlebih dahulu dilakukan Uji Asumsi Klasik.. Hasil penelitian yang diperoleh menunjukkan bahwa rasio likuiditas yang diproksi dengan current ratio dan quick ratio serta rasio profitabilitas yang diproksi dengan return on assets dan return on equity secara simultan berpengaruh signifikan terhadap harga saham pada perusahaan Indeks IDX-30 periode 2018-2019. Adapun secara parsial, Current Ratio berpengaruh positif dan signifikan terhadap harga saham; Quick Ratio berpengaruh negatif dan signifikan terhadap harga saham; Return On Assets tidak berpengaruh signifikan terhadap harga saham; dan Return On Equity tidak berpengaruh signifikan terhadap harga saham pada perusahaan Indeks IDX-30 Periode 2018 – 2019.
PENGGUNAAN FERMENTASI URIN KUDA DAN PUPUK KANDANG KUDA UNTUK MENGOPTIMALKAN PRODUKSI TANAMAN BAWANG DAUN ( Allium fistulosum L.)
Authors: Saputri Mega , Jonni Jonni , Jonni Jonni 
Published: April 2021

Bawang daun merupakan istilah umum yang terdiri dari spesies yang berbeda. Tiga Jenis bawang daun yang banyak dibudidayakan adalah bawang prei atau leek (Allium porum L), kucai (Allium schoecoprasum) dan bawang bakung dan bawang semprong (Allium fistulosum L). Hasil program penelitian dan pengembangan hortikultura di Indonesia pada periode tahun 1989-1994 garapan puslitbang hortikultura belum memprioritaskan bawang daun, namun kenyataan di lapangan bawang daun telah dibudidayakan secara luas di berbagai daerah (wilayah). Tujuan dari proyek usaha mandiri ini : Menganalisis kelayakan usaha budidaya tanaman bawang daun dengan teknologi urin kuda difermentasi dan pupuk kandang kuda dan mengoptimalkan produksi tanaman bawang daun dengan teknologi urin kuda difermentasi dan pupuk kandang kuda Proyeksi Usaha Mandiri ini telah dilaksanakan pada kebun percobaan Politeknik Pertanian Negeri Payakumbuh di Tanjung Pati, dari bulan September sampai Desember 2016. Pelaksanaan Proyek Usaha Mandiri diperoleh hasil produksi bawang daun sabanyak 25 kg dengan harga jual Rp. 15.000 dari hasil produksi diperoleh penerimaan total (TR) Rp. 375.000 dan biaya total (TC) Rp. 872.224. Kesimpulan dari proyek usaha mandiri bawang daun dengan teknologi urin kuda difermentasi dan pupuk kandang kuda memperoleh hasil sebanyak 25 kg, TR Rp. 375.000, TC Rp. 872.224 yang mana proyek mengalami kerugian dengan profitabilitas â€“57 % dan R.C ratio 0,43 dan fermentasi urin kuda dan pupuk kandang kuda belum mampu mengoptimalkan produksi bawang daun pada proyek usaha mandiri ini. Disarankan pada budidaya ini penggunaan teknik fermentasi urin kuda dan pupuk kandang kuda sebaiknya dilakukan pada kondisi lingkungan yang menguntungkan.
On the Syllogistic of G. Boole
Authors: Chernoskutov Yu. Yu. 
Published: April 2021

Introduction. This article focuses on the investigation of Boole’s theory of categorical syllogism, exposed in his book “The Mathematical analysis of Logic”. That part of Boolean legacy has been neglected in the prevailed investigations on the history of logic; the latter provides the novelty of the work presented.Methodology and sources. The formal reconstruction of the methods of algebraic presentation of categorical syllogism, as it is exposed in the original work of Boole, is conducted. The character of Boolean methods is investigated in the interconnections with the principles of symbolic algebra on the one hand, and with the principles of signification, taken from R. Whately, on the other hand. The approaches to signification, grounding the syllogistic theories of Boole and Brentano, are analyzed in comparison, wherefrom we explain the reasons why the results of those theories are different so much.Results and discussion. It is demonstrated here that Boole has borrowed the principles of signification from the Whately’s book “The Elements of Logic”. The interpreting the content of the terms as classes, being combined with methods of symbolic algebra, has determined the core features of Boolean syllogism theory and its unexpected results. In contrast to Whately, Boole conduct the approach to ultimate ends, overcoming the restrictions imposed by Aristotelean doctrine. In particular, he neglects the distinction of subject and predicate among the terms of proposition, the order of premises, and provide the possibility to draw conclusions with negative terms. At the same time Boole missed that the forms of inference, parallel to Bramantip and Fresison, are legitimate forms in his system. In spite of the apparent affinities between the Boolean and Brentanian theories of judgment, the syllogistics of Boole appeared to be more flexible. The drawing of particular conclusion from universal premises is allowable in Boolean theory, but not in Brentanian one; besides, in his theory is allowable the drawing of conclusion from two negative premises, which is prohibited in Aristotelian syllogistic.Conclusion. Boole consistently interpreted signification of terms as classes; being combine with methods symbolic algebra it led to very flexible syllogism theory with rich results.
Las ayudas públicas en la crisis de la COVID-19
Authors: Lopéz Vallés Joaquín , Contreras Delgado de Cos Juan M. 
Published: April 2021

Este trabajo resume los principales aspectos del Marco Temporal de ayudas para hacer frente a la COVID-19 aprobado por la Comisión Europea (CE), así como las medidas de ayuda notificadas por España que han sido aprobadas por la CE hasta la fecha. Se explican las diferencias entre Estados miembros de la Unión Europea y se ofrece una panorámica de los fondos europeos para la recuperación, destacándose la oportunidad que suponen tanto para conseguir los objetivos de digitalización y sostenibilidad medioambiental como para equilibrar, en su caso, las diferencias señaladas. Por último, se desarrolla la relación que cabe esperar de una política pública horizontal como la de competencia para favorecer el objetivo de la sostenibilidad.
Relationship between Mother's Knowledge of Breastfeeding and Exclusive Breastfeeding for Nursing Mothers in the Operational Area of the Sudiang Primary Health Center
Authors: Wahyuni Dian , Rosdianah  , Asriani  
Published: April 2021

Introduction: Exclusive breastfeeding is breastfeeding only in the first 6 months without drinks or other additional foods. There are several factors that influence breastfeeding behavior, one of which is the mother's knowledge. This research was conducted to determine whether there is a relationship between maternal knowledge and exclusive breastfeeding behavior
Methods: This study used an analytic observational study design with a cross sectional approach. The sample of this research is breastfeeding mothers who have children aged 6-24 months in the working area of Sudiang Health Center. Samples were taken using purposive sampling technique with a total sample of 262 people. Data was collected by filling out questionnaires by respondents.
Results: The results showed that mothers
Introduction: Exclusive breastfeeding is breastfeeding only in the first 6 months without drinks or other additional foods. There are several factors that influence breastfeeding behavior, one of which is the mother's knowledge. This research was conducted to determine whether there is a relationship between maternal knowledge and exclusive breastfeeding behavior
Methods: This study used an analytic observational study design with a cross sectional approach. The sample of this research is breastfeeding mothers who have children aged 6-24 months in the working area of Sudiang Health Center. Samples were taken using purposive sampling technique with a total sample of 262 people. Data was collected by filling out questionnaires by respondents.
Results: The results showed that mothers who have high knowledge and provide exclusive breastfeeding are more than 56.1%. Analysis of the two variables shows the value of p = 0.000. Statistically, there is a significant relationship between maternal knowledge and exclusive breastfeeding behavior
Conclusion: The conclusion of this research is that there is a relationship between maternal knowledge and the behavior of exclusive breastfeeding in the working area of the Sudiang Health Center.
Keywords: Mother's Knowledge; Breastfeeding; Exclusive Breastfeeding
who have high knowledge and provide exclusive breastfeeding are more than 56.1%. Analysis of the two variables shows the value of p = 0.000. Statistically, there is a significant relationship between maternal knowledge and exclusive breastfeeding behavior
Conclusion: The conclusion of this research is that there is a relationship between maternal knowledge and the behavior of exclusive breastfeeding in the working area of the Sudiang Health Center.
Keywords: Mother's Knowledge; Breastfeeding; Exclusive Breastfeeding
KETIDAKLANGSUNGAN EKSPRESI DALAM JUDUL CERITA RUBRIK “NAH INI DIA” HARIAN POS KOTA
Authors: Lewa Andi Hallang , Santoso Budi 
Published: April 2021

Indirrect expression is widely used in writing news on the mass media, including short stories in newspapers. This paper tries to describe indirrect expressions in the title of the storiy on Poskota daily’s Column "Nah Ini Dia". Data is taken from the title of the storiy on Poskota daily’s Column "Nah Ini Dia", 2020, March-April edition. The research method uses descriptive qualitative methods. Documentation techniques used in collecting data. Data analysis used Riffatere's indirrect expressions theory with focused on analysing displacing of meaning, distorcing of meaning, and creating of meaning. The results show that indirrect expression is occur due to displacing of meaning, distorcing of meaning, and creating of meaning. Displacing of meaning appear in the form of figurative language such as metaphor, personification, periphrasis, and euphemism. distorcing of meaning appears in the form of ambiguity, contradiction, and irony. Creatiing of meaning appears in the form of simitri and two types of rhythm: assonance and consonance. Using indirect expressions make the title of the story more polite and have poetic sense.
An EMT-Related Gene Signature for Predicting Response to Adjuvant Chemotherapy in Pancreatic Ductal Adenocarcinoma
Authors: Feng Zengyu , Li Kexian , Lou Jianyao , Wu Yulian , Peng Chenghong 
Published: April 2021

BackgroundFor pancreatic ductal adenocarcinoma (PDAC) patients, chemotherapy failure is the major reason for postoperative recurrence and poor outcomes. Establishment of novel biomarkers and models for predicting chemotherapeutic efficacy may provide survival benefits by tailoring treatments.MethodsUnivariate cox regression analysis was employed to identify EMT-related genes with prognostic potential for DFS. These genes were subsequently submitted to LASSO regression analysis and multivariate cox regression analysis to identify an optimal gene signature in TCGA training cohort. The predictive accuracy was assessed by Kaplan–Meier (K-M), receiver operating characteristic (ROC) and calibration curves and was validated in PACA-CA cohort and our local cohort. Pathway enrichment and function annotation analyses were conducted to illuminate the biological implication of this risk signature.ResultsLASSO and multivariate Cox regression analyses selected an 8-gene signature comprised DLX2, FGF9, IL6R, ITGB6, MYC, LGR5, S100A2, and TNFSF12. The signature had the capability to classify PDAC patients with different DFS, both in the training and validation cohorts. It provided improved DFS prediction compared with clinical indicators. This signature was associated with several cancer-related pathways. In addition, the signature could also predict the response to immune-checkpoint inhibitors (ICIs)-based immunotherapy.ConclusionWe established a novel EMT-related gene signature that was capable of predicting therapeutic response to adjuvant chemotherapy and immunotherapy. This signature might facilitate individualized treatment and appropriate management of PDAC patients.
High-Throughput Absolute Quantification Sequencing Revealed Osteoporosis-Related Gut Microbiota Alterations in Han Chinese Elderly
Authors: Wei Muhong , Li Can , Dai Yu , Zhou Haolong , Cui Yuan , Zeng Yun , Huang Qin , Wang Qi 
Published: April 2021

ObjectiveAccumulative evidence suggests that gut microbiota play an important role in bone remodeling and hence bone health maintenance. This study aimed to explore the association of gut microbiota with the risk of osteoporosis and to identify potential disease-related taxa, which may be promising targets in osteoporosis prevention and treatment in the future.MethodsAbsolute quantification 16S ribosomal RNA gene sequencing was used to detect absolute and relative abundances of gut microbiota in 44 patients with osteoporosis and 64 controls. In combination with one of our previous studies, a total of 175 samples were involved in the relative abundance analysis.ResultsCompared with the controls, the patients with osteoporosis had higher absolute and relative abundances of Bacteroidetes phylum, and Bacteroides and Eisenbergiella genera. The absolute abundances of Clostridium_XlVa, Coprococcus, Lactobacillus, and Eggerthella genera increased, and that of the Veillonella genus decreased in the osteoporosis group. As for relative abundance, that of the Parabacteroides and Flavonifractor genera increased, whereas that of the Raoultella genus decreased in the osteoporosis group. Controlling for potential confounders, the associations of Clostridium_XlVa, Coprococcus, and Veillonella genera with the risk of osteoporosis did not maintain significance. Ridge regression analysis suggested that Bacteroides is associated with reduced bone mineral density (BMD) and T-score at lumbar spines, and Anaerovorax is associated with increased BMD at the femoral neck. Functional predictions revealed that 10 Kyoto Encyclopedia of Genes and Genomes pathways were enriched in the osteoporosis group.ConclusionsGut microbiota compositions may contribute to the risk of osteoporosis. Several specific taxa and functional pathways are identified to associate with reduced bone density, thus providing epidemiologic evidence for the potential role of aberrant gut microbiota in osteoporosis pathogenesis.
Near-Infrared Spectroscopy Assessment of Tissue Oxygenation During Selective Cerebral Perfusion for Neonatal Aortic Arch Reconstruction
Authors: Huang Chi-Hsiang , Wang Yi-Chia , Chou Hen-Wen , Huang Shu-Chien 
Published: April 2021

Objective: Optimal selective cerebral perfusion (SCP) management for neonatal aortic arch surgery has not been extensively studied. We induced mild hypothermia during SCP and used the tissue oxygenation monitor to ensure adequate perfusion during the cardiopulmonary bypass (CPB).Methods: Eight cases were recruited from September 2018 to April 2020. SCP was maintained at 30°C, and CPB was adjusted to achieve a mean right radial artery pressure of 30 mmHg. The near-infrared tissue saturation (NIRS) monitor was applied to assess the right and left brain, flank, and lower extremity during the surgery.Results: During surgery, the mean age was 4.75 days, the mean body weight was 2.92 kg, the CPB duration was 86.5 ±18.7 min, the aortic cross-clamp time was 46.1 ± 12.7 min, and the SCP duration was 14.6±3.4 min. The brain NIRS before, during, and after SCP was 64.2, 67.2, and 71.5 on the left side and 67.9, 66.2, and 70.1 on the right side (p = NS), respectively. However, renal and lower extremity tissue oxygenation, respectively decreased from 61.6 and 62.4 before SCP to 37.7 and 39.9 after SCP (p &lt; 0.05) and then increased to 70.1 and 90.4 after full body flow resumed. No stroke was reported postoperatively.Conclusion: SCP under mild hypothermia can aid in efficient maintenance of brain perfusion during neonatal arch reconstruction. The clinical outcome of this strategy was favorable for up to 20 min, but the safety duration of lower body ischemia warrants further analysis.
Practical Strategies Using Medical Cannabis to Reduce Harms Associated With Long Term Opioid Use in Chronic Pain
Authors: MacCallum Caroline A. , Eadie Lauren , Barr Alasdair M. , Boivin Michael , Lu Shaohua 
Published: April 2021

Background:Chronic non-cancer pain (CNCP) is estimated to affect 20% of the adult population. Current United States and Canadian Chronic non-cancer pain guidelines recommend careful reassessment of the risk-benefit ratio for doses greater than 90 mg morphine equivalent dose (MED), due to low evidence for improved pain efficacy at higher morphine equivalent dose and a significant increase in morbidity and mortality. There are a number of human studies demonstrating cannabis opioid synergy. This preliminary evidence suggests a potential role of cannabis as an adjunctive therapy with or without opioids to optimize pain control.Methods:In 2017, the Canadian Opioid Guidelines Clinical Tool was created to encourage judicious opioid prescribing for CNCP patients and to reevaluate those who have been chronically using high MED. Mirroring this approach, we draw on our clinical experiences and available evidence to create a clinical tool to serve as a foundational clinical guideline for the initiation of medical cannabis in the management of CNCP patients using chronic opioid therapy.Findings:Following principles of harm reduction and risk minimization, we suggest cannabis be introduced in appropriately selected CNCP patients, using a stepwise approach, with the intent of pain management optimization. We use a structured approach to focus on low dose cannabis (namely, THC) initiation, slow titration, dose optimization and frequent monitoring.Conclusion:When low dose THC is introduced as an adjunctive therapy, we observe better pain control clinically with lower doses of opioids, improved pain related outcomes and reduced opioid related harm.
Evaluation of Aqueous Flare Intensity in Eyes Undergoing Intravitreal Bevacizumab Therapy to Treat Neovascular Age-Related Macular Degeneration
Authors: Dolar-Szczasny Joanna , Bucolo Claudio , Zweifel Sandrine , Carnevali Adriano , Rejdak Robert , Załuska Wojciech , Czarnek-Chudzik Aleksandra , Toro Mario Damiano 
Published: April 2021

Purpose: To evaluate the effect of repeated intravitreal bevacizumab injections on blood-aqueous barrier permeability in eyes with neovascular age-related macular degeneration (AMD).Patients and Methods: Forty-eight consecutive patients with neovascular AMD received 3 intravitreal bevacizumab injections (1 mg) every 30–40 days. Subjects were followed for a period of 4 months and were examined at baseline, 1 day and 1 month after each injection. A control group comprised of 19 neovascular AMD patients waiting to begin anti-vascular endothelial growth factor (VEGF) therapy. Anterior chamber (AC) inflammation was evaluated with biomicroscopy and laser flare photometry.Results: None of the subjects treated with bevacizumab had detectable ocular inflammation during follow-up. An analysis for variance (ANOVA) of the mixed-effects model has shown neither an effect between treatment and control group (p = 0.921), nor over the time course of the follow-up (p = 0.773). Before treatment, median AC inflammation was 6.7 photons/ms (range: 3.5–18.2 photons/ms). One month after the first, second, and third injections, median laser flare was 6.4, 6.8, and 6.6 photons/ms, respectively, none of which were significantly different from baseline (all p &gt; 0.05). Blood-aqueous barrier permeability did not change between injections and was not different from the control group.Conclusion: Inflammation induced by intravitreal bevacizumab was not detected by examination or flare photometry. This suggests that monthly bevacizumab dosing seems to be safe. The absence of AC inflammation could also reflect the known anti-inflammatory properties of anti-VEGF agents.
Utilization of Inpatient Mental Health Care in the Rhineland During the COVID-19 Pandemic
Authors: Zielasek Jürgen , Vrinssen Jürgen , Gouzoulis-Mayfrank Euphrosyne 
Published: April 2021

Background: During the Coronavirus-19 (COVID-19) pandemic, considerable changes occurred in the utilization of mental health care.Objectives: We conducted an analysis of the changes of inpatient and day patient mental health care utilization in an association of psychiatric hospitals during the COVID-19 pandemic.Materials and Methods: We used the statistics database of the association of nine psychiatric hospitals of the Rhineland Regional Council (Landschaftsverband Rheinland, LVR). We compared the case numbers of spring 2019 and spring 2020 and analyzed alterations in the diagnostic spectrum. Finally, we analyzed the age, gender, and diagnoses of patients tested positive for COVID-19.Results: A total of 25,612 inpatient psychiatric hospital admissions were assessed. Case rates decreased by 25% during the COVID-19 pandemic. Changes varied between diagnostic groups, and there were even increases in case numbers for certain diagnoses. Women and patients of higher ages were overrepresented among psychiatric inpatients with COVID-19.Conclusions: The COVID-19 pandemic resulted in considerable reductions in the total number of mental health-care admissions and in changes in the diagnostic spectrum. The results may be explainable by deferrals of elective hospital admissions during the acute phase of the pandemic and by destabilizing effects of the pandemic and social distancing on people with mental disorders.
PERTURBAÇÃO DO SOSSEGO ALHEIO E POLUIÇÃO SONORA NA CIDADE DE MACEIÓ CAUSADA POR APARELHO SONORO ACOPLADO, OU NÃO, A VEÍCULO AUTOMOTOR PAREDÃO NOS FINAIS DE SEMANA E FERIADOS
Authors: Silva Lucio Santos da 
Published: April 2021

A perturbação do sossego alheio e poluição sonora causada por aparelho sonoro acoplado, ou não, a veículo automotor Paredão nos finais de semana e feriados ocupam em 33 % as linhas de chamada de emergência da Polícia Militar(190). Isto é um percentual altíssimo em comparação a outras situações que demandam a intervenção do aparato policial, a exemplo do furto, roubo, violência doméstica, lesão corporal, violência contra a criança e o adolescente, tentativa de homicídio, combate ao tráfico de drogas. O que tem levado o policial militar, atendente do 190, e principalmente, aquele que compõe a guarnição do policialmento ostensivo a um trabalho exaustivo. Pois, em sua maioria, o solicitante não quer se identificar no ato da denúncia, não querendo se envolver com a situação, alegando temer possíveis represálias da parte do contraventor. Mesmo assim, uma guarnição é enviada ao local de denúncia, solicitando que se baixe o aparelho sonoro, o que resolve a situação, ainda que de forma superficial. Pois que, sem a presença da vítima no local da ocorrência, a polícia militar não poderá conduzi-lo a uma delegacia de Polícia Judiciária para lavratura do TCO (Termo Circunstancial de Ocorrência) nos termos do art. 65 do Dec. Lei 3.688/41, não restando muito a se fazer. O problema é quando a guarnição deixa o loca a viatuara dobra a esquina. O contraventor voltar a aumentar o aparelho sonoro, às vezes, mais ainda, numa forma de deboche. Sendo por isso mesmo, recorrente a mesma vítima ligando várias vezes ao call Center de Emergência para denunciar a mesma situação de perturbação sonora. Tornado o trabalho da polícia ineficiente. Mas ao longo destas páginas apresentaremos sugestões ao poder público estadual e municipal que visam tornar o trabalho da polícia militar no combate a perturbação sonora mais efetivo.