bluuebunny/crossref_metadata_2025_split huggingface dataset:
ALAT PENUNTUN TUNANETRA BAGI PENYANDANG TUNANETRA LINGKUP UNJ BERBASIS ARDUINO DAN KOMPAS
Authors: Ade Riza Priambodo  , Muhammad Rif’an  , Nur Hanifah Yuninda  
Published: March 2021

Man was created perfect but in its development are not all born normal. Humans are born so called in need special, special man in need of them is deaf, blind and tunawicara. Required tools that can significantly impact that is guiding the blind tools can serve as a guiding visually impaired in performing daily activities Research methods used in this study i.e. method using RnD. This research was conducted at the University of Jakarta Country in April 2018, testing is done i.e. test modules, test compass GPS module, test module DF Player, and Test the motor gear box DC
Based on the results of the research there is a compass that the module obtained different results due to the large number of different metals around testing, testing the GPS module obtained as a result of appropriate coordinates realtime guiding tool for visually impaired the test runs, the Player can function DF module fits well, testing module gear box can function in accordance with the specified distance
Abstrak
Manusia diciptakan sempurna namun dalam perkembangannya tidak semua terlahir normal. Manusia yang lahir demikian disebut dengan berkebutuhan khusus, manusia berkebutuhan khusus diantaranya adalah tunarungu, tunawicara dan tunanetra. Maka dibutuhkan alat yang dapat berdampak signifikan yaitu alat penuntun tunanetra dapat berfungsi sebagai penuntun tunanetra dalam melakukan aktifitas sehari hari. Metode penelitian yang digunakan dalam penelitian ini yaitu menggunakan metode RnD. Penelitian ini dilakukan di Universitas Negri Jakarta pada bulan April 2018, Pengujian yang dilakukan yaitu menguji modul kompas, menguji modul GPS, menguji modul DF Player, dan Menguji motor gear box DC
Berdasarkan hasil yang penelitian yang didapatkan bahwa modul kompas terdapat hasil yang berbeda beda dikarenakan banyaknya unsur logam disekitaran pengujian, pengujian modul GPS didapatkan hasil kordinat sesuai realtime selama alat penuntun tunanetra berjalan, pengujian modul DF Player dapat berfungsi sesuai dengan baik, pengujian modul gear box dapat berfungsi sesuai dengan jarak yang ditentukan.
Factors to Improve Quality for Older Patients in the Emergency Department: A Qualitative Study of Patient Trajectory
Authors: Brauwer Isabelle De , Cornette Pascale , D’Hoore William , Lorant Vincent , Verschuren Franck , Thys Frédéric , Aujoulat Isabelle 
Published: March 2021

Abstract
BackgroundManaging older people in the emergency department remains a challenge. We aimed to identify the factors influencing the care quality of older patients in the emergency department, in order to fine-tune future interventions for older people, taking into account the naturalistic context of the ED.Methods. This is a qualitative study of some 450 hours of observations performed in three emergency departments selected for their diverse contexts. We performed seventy observations of older patient trajectories admitted to the emergency department. Themes were extracted from the material using an inductive reasoning approach, to highlight factors positively or negatively influencing management of patient’s trajectories, in particular those presenting with typically geriatric syndromes.Results Four themes emerged: no geriatric flow routine; risk of discontinuity of care; unmet basic needs and patient-centered care; complex older patients: unwelcome in EDs? ConclusionsThe overall process of care was based on an organ- and flow-centered paradigm, which ignored older people’s specific needs and exposed them to discontinuity of care. Their basic needs were neglected and, when their management slowed the emergency department flow, older people were perceived as unwelcome. Findings of our study can inform the development of interventions about the influence of context and organizational factors.
Treatment of Advanced Lunate Bone Necrosis by Individualized Bone Cement Prosthetic Replacement
Authors: Yuan Cheng-song , Tang Yao , Li Hong-tao , Chen Yong-hua , Ma Lin , Zhai Hong-xia , Liu Jun-peng , Mu Mi-duo , Zhang Xuan , Tang Kang-lai 
Published: March 2021

Abstract
Objective: The aim of this study is to prospectively analyze the clinical effect of an individualized bone cement prosthetic replacement in treating advanced lunate bone necrosis. Methods: Since 2006, a total of 19 Lichtman stage III and IV aseptic lunate bone necrosis patients with a wrist height ratio ≥0.5 were included, the last visit time was three years after operation. The statistically significant differences in range of motion, (Visual Analogue Scale/Score, VAS) score, Cooney score, grasp force, wrist height ratio (to the capitate bone), and radio scaphoid angle of the affected wrist joint were observed before the operation and at the last visit (p<0.05). Results: There were no statistically significant differences in the axial line and maximum diameter of the lunate bone between the healthy side and the affected side (p>0.05). Conclusion: The surgical method can restore the original anatomic structure of wrist joint, play an important role in recovering the movement function of wrist joint, and has a significant effect on wrist pain and few complications.
Climate Change Induced Shocks, Consequent Impacts, Vulnerability and Farmers Endeavor to Adapt in Northern Highland: Implication for Designing Household and Community Level Strategies
Authors: Assefa Daniel , Haile Firafis 
Published: March 2021

Abstract
BackgroundDespite future emissions, the world is already exposed to further warming, largely due to past emissions. If global society continues to emit greenhouse gases at current rates, the average global temperature could rise in alarming rate. The consequent shocks such as heat waves, sea level rises, storms, cyclones, flooding and droughts, which currently hit hard are also expected to be more severe and more frequent in the future across the globe. Its impacts will be very devastating to livelihoods of the world in general and farming community in particular. Therefore, adaptation appears as the best mechanisms to dampen vulnerability and increase capacity to resist to climate change.MethodologyMixed research approach i.e., qualitative and quantitative methods along with phenomenological design were used. While sample districts, elder farmers for focus group discussions and experts and development agents for intensive interviews were selected purposively, Kebeles and household heads for survey data selected using proportionate random sampling procedures. Quantitative data collected using semi-structured questionnaire were analysed using descriptive methods and index (Principal Component Analysis). Whereas, qualitative data collected using discussion and interview guiding checklists were transcribed, coded, organized with resembles and analysed thematically. Major findings & ConclusionIncrease in temperature, change in rainfall including shift in raining periods, shortage and variability of rain, frequent occurrence of drought, crop pests and animal disease were major branded climate change induced shocks in the area. Land degradation, low productivity of crop and animal production caused due to loss of soil fertility, crop pests, scarcity of pasture and water, and animal disease were the key consequent impacts of climate change induced shocks affected the livelihood. Vulnerability of farmers was very high. To reduce their vulnerability farmers employed many strategies: soil and water resource conservation practices, collecting hay, use of improved seed, fertilizer, pesticides and insecticides even if its use were very poor due to lack of finance. Farmers were at the edge of survival due to interconnected impacts.RecommendationsTherefore, government policies should emphasis on the provision of local context based farming technology packages, strengthening of watershed management practices and development and provision of well-coordinated early warning systems.
Efficacy of acupuncture based on acupoint combination theory for irritable bowel syndrome: study protocol for a multicenter randomized controlled trial
Authors: Sun Jing-wen , Li Zhi-gang , Sun Ming-liang , Li Da , Zhao Jun , Shi Su-hua , Li Hui-xia , Liu Hui-min , Gao Jun-xia , Hu Yu , Zheng Hui , Wang Xin , Xue Rong-dan , Feng Xue , Yu Shu-guang 
Published: March 2021

Abstract
Background: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain, diarrhea or constipation, and changes in defecation patterns. No organic disease has been found to explain these symptoms by routine clinical examination. This study aims to investigate the efficacy and safety of acupuncture therapy for IBS patients based on conventional treatments. We also want to explore the optimal acupoint combination recommended for IBS and clarify the clinical advantage of "multi-acupoint co-effect and synergistic effect".Methods and analysis: A total of 204 eligible patients who meet the Rome IV criteria for IBS will be randomly allocated to receive different acupuncture. Each patient will receive 12 acupuncture treatments over four weeks and will be followed up for four weeks. The primary outcome is the IBS-symptom severity score (IBS-SSS). The secondary outcomes include the Bristol stool form scale(BSFS), the work and social adjustment score (WSAS), the IBS-quality of life (IBS-QOL), self-rating anxiety scale (SAS), and the self-rating depression scale (SDS). Both the primary outcome and the secondary outcomes measures are collected at baseline, 2 weeks, and 4 weeks of the intervention, 6 weeks, and 8 weeks after the intervention.Ethics and dissemination: The entire project has been approved by the ethics committee of Beijing University of Chinese Medicine ( 2020BZYLL0903 ) .Discussion: This is a multicenter randomized controlled trial for IBS in China. This may shed light on the efficacy of acupuncture as an alternative to IBS. The results of the trial will be disseminated in peer-reviewed publications. Trial registration: Chinese Clinical Trials Register, ID: ChiCTR2000041215.First registered on 12 December 2020. http://www.chictr.org.cn/.
Letter on “Sharing trial results directly with trial participants and other stakeholders after the SARS-CoV-2 pandemic hit the UK – experience from the ActWELL trial”
Authors: Bruhn Hanne , Anderson Annie S. , Hickman Amy , Macaskill E. Jane , Treweek Shaun 
Published: March 2021

Abstract
After the SARS-CoV-2 pandemic took hold in the UK the ActWELL trial team’s plans to present the trial results to participants and other stakeholders had to change. Instead of face-face events, three online events were planned and hosted successfully. In this article we describe the choices made in planning and organisation of the online events including things we would do differently if we were to do it again. We think that online events are a useful platform when informing participants and other stakeholders of the results of your trial, even beyond the SARS-CoV-2 pandemic and we hope this article can help other trial teams to plan their own online events.
Exploring the Association and Dissociation Between Lectures and Practicums in the Process of Learning Experience in Psychiatric and Mental Health Nursing Education: a Qualitative Study in Japan
Authors: Odachi Ryo , Yada Hironori , Adachi Keiichiro 
Published: March 2021

Abstract
Objective: This study aimed to clarify the process of students’ experience of learning to identify association and dissociation between lectures and practicums in psychiatric and mental health nursing (PMHN) education at a university.Methods: An interview survey of 21 students from a regional national university in Japan was conducted, and the interview data were analyzed with a modified grounded theory approach.Results: The analysis identified 12 categories and 32 concepts regarding the process of learning experience in PMHN among university nursing students. Through lectures, the students accomplished “self-developmental knowledge retention” or “acquisition of superficial knowledge about PMHN” toward “formation of learning attitude based on life experience.” The outcomes of lectures significantly affected practicums; the former possibly resulted in “non-discovery of significance of practicums;” however, the latter possibly approached “developmental self-learning.”Discussion: The association between students’ interests based on life experience and contents of lectures affected practicums, and the lecture design readily imaginable from students’ experience was desirable. Practicums must be built on teaching strategies that make students aware of the particularity of communication.
Hidden Blood Loss and Factors in Shoulder Arthroscopy Surgery: A Review of 59 Patients
Authors: Jiangbo Nie , Jin Mingchao , Fang Tianshun , Liu Xi , Jiang Haowei , Li Jianyou 
Published: March 2021

Abstract
Purpose: Subacromial impingement syndrome (SIS) and its related rotator cuff tears are the most important cause of shoulder joint pain, which has recently received greater attention. Arthroscopy is a safe, effective, and minimally invasive procedure for the treatment of stage Ⅱ or Ⅲ SIS. Previous studies have reported that little blood loss usually occurs during this procedure. However, significant perioperative hidden blood loss (HBL) is often overlooked. In this respect, we herein aimed to investigate the amount of HBL and identify its possible risk factors.Methods: We enrolled 59 patients with SIS who received shoulder arthroscopy between December 2019 and June 2020 in this study. The clinical data recorded included the height of patients, weight pre- and postoperative hematocrit (Hct), which were used to calculate HBL using Gross’s formula. We analyzed the risk factors, including sex, age, BMI (body mass index), stage of SIS, diabetes, hypertension, and operative time using multivariate linear regression analysis.Results: Our results revealed that the mean of HBL was 341.4 ± 214.9 mL, while that of the postoperative Hb loss was 13.3 ± 8.0 g/L. The incidence of postoperative anemia was significantly associated with HBL (χ2 = 14.496, P < 0.001). Furthermore, multivariate linear regression analysis demonstrated that all seven factors, including gender (P = 0.698), age (P = 0.553), BMI (P = 0.854), stage of SIS (P = 0.906), diabetes (P = 0.984), hypertension (P = 0.532), and operative time (P = 0.645), were not significantly associated with HBL. Conclusion: Findings from this study show that postoperative HBL following shoulder arthroscopy was significant, which can aggravate anemia or lead to secondary anemia, thus should not be neglected.
Urinary exosomal microRNA-96 and microRNA-183 expression as potential biomarkers of bladder cancer
Authors: El-Shal Amal , Shalaby Sally , Abouhashem Safwat , Elbary Eman Abd , Azazy Samir , Rashad Nearmeen , Sarhan Walaa 
Published: March 2021

Abstract
Background: Because of low sensitivity and specificity of the currently available urine markers for bladder cancer (BC) detection and painful cystoscopy procedure, our study was aimed to evaluate expression of urinary exosomal microRNA (miR)-96 and miR-183 as probable noninvasive and accurate biomarkers for the diagnosis and follow up of BC. Methods and results: Using quantitative real-time polymerase chain reaction; Expression of exosomal miR-96 and miR- 183 in the urine samples of 51 patients with BC, 21 patients with benign urinary bladder lesions and in 24 normal individuals as control group. Our study results showed higher expressions of both miR-96 and miR-183 in urine of BC patients in comparison with control group (P <0.001 for each). Analysis of receiver-operating characteristic curve demonstrated that each microRNA had good sensitivity and specificity for differentiating BC patients from non-BC patients (miR-96; 80.4% and 91.8%; and miR-183, 78.4% and 81.6% respectively) compared to cytology (37.3% and 100%). In addition, it was obvious that the sensitivity and specificity of combined miR-96 and miR-183 for the diagnosis of BC reached 88.2%% and 87.8%, respectively, which were higher than each one alone. We also found that expression of miR-96 and miR-183 with lymph node invasion, advancing grade, and pathological stage was significantly increased. After surgery, collected urine samples showed significantly lower expression of microRNA (miR-96: P < 0.001; and miR-183, P = 0.002). Conclusion: In conclusion, miR-96 and miR-183 in urine are promising diagnostic tumor markers for BC; particularly, when they combined with each other or with urinary cytology.
A Nomogram Based on Glycolysis-related Gene Expression Profilings Serve as a Novel Prognosis Risk Classifiers for Human Hepatocellular Carcinoma
Authors: Zhang Lingyu , Li Yu , Dai Yibei , Wang Danhua , Wang Xuchu , Cao Ying , Liu Weiwei , Tao Zhihua 
Published: March 2021

Abstract
Metabolic pattern reconstruction is an important element in tumor progression. The metabolism of tumor cells is characterized by the abnormal increase of anaerobic glycolysis, regardless of the higher oxygen concentration, resulting in a large accumulation of energy from glucose sources, and contributes to rapid cell proliferation and tumor growth which is further referenced as the Warburg effect. We tried to reconstruct the metabolic pattern in the progression of cancer to screen which genetic changes are specific in cancer cells. A total of 12 common types of solid tumors were enrolled in the prospective study. Gene set enrichment analysis (GSEA) was implemented to analyze 9 glycolysis-related gene sets, which are closely related to the glycolysis process. Univariate and multivariate analyses were used to identify independent prognostic variables for the construction of a nomogram based on clinicopathological characteristics and a glycolysis-related gene prognostic index (GRGPI). The prognostic model based on glycolysis genes has the highest area under the curve (AUC) in LIHC (Liver hepatocellular carcinoma). 8-gene signatures (AURKA, CDK1, CENPA, DEPDC1, HMMR, KIF20A, PFKFB4, STMN1) were related to overall survival (OS) and recurrence-free survival (RFS). Further analysis demonstrates that the prediction model can accurately distinguish between high- and low-risk cancer patients among patients in different clusters in LIHC. A nomogram with a well-fitted calibration curve based on gene expression profiles and clinical characteristics improves discrimination in internal and external cohorts. Furthermore, the altering expression of metabolic genes related to glycolysis may contribute to the reconstruction of the tumor-related microenvironment.
Anatomical Variations and Dimension of the Intracranial Vertebral Artery: Evaluation With Multidetector Computed Tomography Angiography
Authors: Omotoso Bukola , Harrichandparsad Rohen , Satyapal Kapil , Moodley Indheresan , Lazarus Lelika 
Published: March 2021

Abstract
The intracranial segment of the vertebral artery (VA) is the unique part of the artery where the two VAs join to form a single vascular channel, viz. the basilar artery. In addition to this typical description, anatomical variations have been described; the presence of anatomical variation has been associated with some pathological processes, neurological complications, and the risk of vascular diseases in the posterior circulatory territory. We evaluated the typical anatomical features and variations of the VA4 component of the VA in a South African population to provide useful data on the prevalence of variation and morphometry of the distal VA. The study is an observational, retrospective chart review of 554 consecutive South African patients (Black, Indian, and White) who had been examined with multidetector computed tomography angiography (MDCTA) from January 2009 to September 2019. We observed various anatomical variations in the VA4 segment of the VA. We report the incidence of VA hypoplasia, hypoplastic terminal VA, and atresia. Fenestration and duplicate posterior inferior cerebellar artery (PICA) origin were also observed. The left intracranial VA was significantly larger than the right. Our study shows that anatomical variation of the intracranial VA is common in the population studied, with a total prevalence of 36.5%. Imaging of the entire course of the VA from the origin to the point of convergence to form the basilar artery may be necessary to decide a treatment strategy for interventions in the vicinity of the VA.
System Design and Experimental Research on the Tangential Ultrasonic Vibration-assisted Grinding Gear
Authors: Bie Wenbo , Zhao Bo , Zhao Chongyang , Yin Long , Guo Xingchen 
Published: March 2021

Abstract
Gear plays an important role in transmitting motion and power system, and a new promising process should be utilized to enhance the machining accuracy and performance. In this paper, the ultrasonic vibration was superimposed into the gear to carry out the tangential ultrasonic vibration-assisted grinding gear (TUVAGG). The longitudinal resonant vibration system was designed based on the non-resonant theory. Firstly, the gear was simplified into a disc with the diameter of the reference circle, and the dynamic equation of each part was erected respectively. Then the frequency equation was derived according to the coupling conditions of the force and displacement during the combined surface of the vibration system. Simultaneously, the characteristic of displacement for the vibration system was also obtained. Secondly, the vibration system composed of the simplified disc and the gear was simulated by the finite elements analysis method, and verified by the resonant measurement experiment respectively. The measurement results exhibited a good agreement with the theoretical. Finally, the effectiveness of the vibration system was verified through the ultrasonic vibration-assisted grinding gear test. It was found that compared with the conventional grinding gear (CGG), the normal grinding force and tangential grinding force was reduced by 7.4-28.2% and 8.9-18.9% respectively during TUVAGG. Besides, the grinding temperature and the surface roughness was declined by 7.6-25.7% and 8.6-21.8% respectively, and the residual compressive stress of tooth surface was elevated by 13.2-29.3%. It was concluded that the non-resonant theory was suitable for the designation of longitudinal vibration system for TUVAGG, and also provided a novel process technology for gear machining.
The ratio of HDL-C to apoA-I interact with free triiodothyronine to modulate coronary artery disease risk
Authors: Li Li , Lu Wei , Li Feng , Yu Lei , Xiao Jianqiang , Cai Gaojun 
Published: March 2021

Abstract
Objective: The present research was carried out to explore the correlation between high-density lipoprotein cholesterol (HDL-C)/ apolipoprotein A-I (apoA-I) ratio and serum free triiodothyronine (FT3) and their interaction on the risk of coronary artery disease (CAD). Methods: A total of 1,686 patients underwent selective coronary angiography, including 1,279 CAD patients and 407 controls were enrolled in the present study. The subjects were divided into three groups according to tertiles of HDL-C/apoA-I. Binary logistic regression analysis was used to evaluate the interaction of HDL-C/apoA-I and FT3 on the risk of CAD.Results: The group with highest HDL-C/apoA-I had the lowest FT3 levels. Multiple linear regression analysis showed that HDL-C/apoA-I were negatively associated with FT3 after adjusting age, sex, body mass index (BMI), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) and apolipoproteinB (ApoB). Logistic regression model showed that high HDL-C/apoA-I (>0.89mmol/g) and high FT3 level (>4.5pmol/l) were protective factor for CAD. Patients with the lower HDL-C/ apoA-I (≤0.89mmol/g) and FT3 level (≤4.5pmol/l) have an increased risk of CAD (OR =2.441, P=0.000, S =1.13, AP=0.068, AP* = 0.116, RERI=0.168).Conclusions: Lower HDL-C/ apoA-I was risk factor for CAD and there was a positive interaction between HDL-C/ apoA-I and FT3 on the risk of CAD.