bluuebunny/crossref_metadata_2025_split huggingface dataset:
Some Problems in Teaching the Methods of Statistical Data Analysis and Opportunities of Modern Information Technologies for their Solution
Authors: Kovalev A. A. , Ignatenko V. A. , Yadchenko A. A. 
Published: November 2021

The problems in teaching the methods of statistical data analysis in evidencebased medicine place high demands on their application. The rigor of the approach requires extensive knowledge in both the direct professional sphere and in areas of knowledge that go far beyond the limits of medicine. It is not enough to simply type groups for the study or calculate average values and draw some conclusions based on this. It is important to recruit groups and evaluate the statistical parameters of the obtained results correctly. Moreover, it is requisite to know the purpose of the research, formulate the appropriate hypotheses even before the beginning of the experiment [1] or data collection, and not to invent them during the analysis of an array of heterogeneous numbers and names when writing articles. The material of data processing presented at the level of schemes and algorithms in combination with the use of the appropriate programs is greatly simplified and, most importantly, streamlined. In this case, the subject of statistics is perceived not as something abstract, but as a complex component of the principles of evidencebased medicine, without detaching it from specialized training.The involvement of specialists of the core subjects of the university sharing the examples of studies using the statistical processing and planning methods into the training will make it possible to improve orientation in a variety of the existing statistical methods of data processing, as well as to understand the importance and relevance of the use of statistics in medical research.
The Response of Tumor Microenvironment to Radiation Therapy: Analysis of the Disease-Free Survival of Patients with Endometrioid Adenocarcinoma of the Corpus Uteri
Authors: Zinovkin D. A. , Nadyrov E. A. 
Published: November 2021

Objective: to identify the threshold values of FoxP3, CD56, PGRMC1, and Galectin-1 expression, to analyze the survival rate of female patients based on the obtained threshold values, to determine the statistical differences in groups depending on the presence/absence of radiotherapy.Mаteriаl аnd methods. The group with radiotherapy (LT+) included 42 female patients, the group without radiotherapy (LT-) included 38. The ROC-analysis was performed to determine the threshold values. The analysis of the survival rate was performed using the logrank test. The groups were compared using the tables 2×2 (Fisher's twosided test), as well as the odds ratio (OR) was calculated. The differences were considered statistically significant at p < 0.05.Results. The study of the Galectin-1 parenchymatous expression showed that statistically significant differences (p<0.0001) were revealed in the study of the relapsefree survival rate based on the obtained threshold value. Gamma ray therapy reduced the parenchymatous expression of Galectin-1 below the threshold value (OR = 0.490 95% CI 0.288-0.800). The analysis of the relapsefree survival rate on the basis of the obtained threshold value of the stromal expression of Galectin-1 revealed statistically significant differences (p = 0.0002). Gamma ray therapy reduced the stromal expression of Galectin-1 below the threshold value (OR = 0.289 95 % CI 0.112-0.742).Conclusion. At a low relapsefree survival rate, a statistically significant increase above the threshold values of the parenchymatous (p < 0.0001) and stromal (p = 0.0002) Galectin-1 expression was observed most frequently.
A healthcare organizational model of secondary prevention of cervical cancer among women of reproductive age
Authors: Harelik T. M. , Naumov I. A. 
Published: November 2021

Objective: to develop a healthcare organizational model of secondary prevention of cervical cancer. Material and methods. The work analyzes the quality of medical care given to women of reproductive age living in Grodno region in whom cases of cervical intraepithelial neoplasia and cervical cancer were detected from 2010 to 2019. On the basis of the results of questioning of 200 women who had been treated in Oncology Ward No.3 of Grodno University Clinic, the most significant risk factors of the development of the pathology were identified. Statistical processing was performed by means of the program «Statistica» 10.0.Results. An effective model of secondary prevention of cervical cancer has been developed: from 2015 to 2019 compared to the previous quinquennium the detectability of cervical intraepithelial neoplasia and non-invasive cervical cancer increased by more than 17 % and 25 %, and the average parameters of the newly diagnosed morbidity were 69.97 ± 2.42 and 19.91 ± 2.28 per 100,000 women of reproductive age (p < 0.05). This made it possible to take timely measures for carcinogenesis interruption.Conclusion. The implementation of the healthcare organizational model of secondary prevention of cervical cancer contributes to improvement of the quality of medical care, and, therefore, maintainance of perspective realization of the child-bearing function for women of reproductive age.
Surgical anatomy of anastomoses of the umbilical artery
Authors: Kuzmenko A. V. 
Published: November 2021

Objective: to identify the variants of the development of anastomoses and their number in the umbilical artery.Material and methods. 206 dead bodies of men (22–82 years of age) and 113 dead bodies of women (32–93 years of age) who had died of causes not related to pelvic pathology were used as the material for the study. The preparation method, vascular injection method, and statistical method were used to achieve the objective.Results. It has been established that the anastomoses of the umbilical artery in both the men and women are most often found in the proximal third of the artery, significantly more rarely — in its middle third. We have determined no linear correlation between the sizes of the diameters of the umbilical artery and the sizes of the diameters of its arterial anastomoses on both the sides of the pelvic cavity in the females and on the right side in the males but have found such a correlation on the left side in the males.Conclusion. The performed study has demonstrated that anastomoses of the umbilical artery in males and in females have a definite pattern of their origination.
Dirofilariasis of the pleura
Authors: Tishchenko G. V. , Shalyga A. I. 
Published: November 2021

Dirofilariasis is the most common transmissible zoonotic nematodosis in Europe, whose clinical manifestations are caused by the migration of immature helminths through human tissues or internal organs. Clinically, it is characterized by slow development and a long-term course, and morphologically — by chronic granulomatous inflammation, often with microabscess.The work presents the description of a clinical case of dirofilariasis of the pleura, the diagnosis of which was performed only at the stage of the histological examination of the surgical material.
Analysis of clinically approved guidelines for the treatment of patients with eosinophilic esophagitis
Authors: Chechenkova E. V. , Savanovich I. I. 
Published: November 2021

Objective: to present modern views of the professional medical communities of the USA, Europe and Russian Federation on the issue of eosinophilic esophagitis (EoE) published in the form of clinically approved recommendations and guidelines for the treatment of patients with this pathology.Material and methods. To achieve the above objective, we analyzed modern literary sources dealing with this issue.Results. We have reviewed the main clinical guidelines on this topic taking into account the comparison of methodological aspects, recommendations and their results, and highlighted the main problems associated with the diagnosis and treatment of patients with eosinophilic esophagitis.Conclusion. Over the past years, the study of EoE has reached a qualitatively new level. However, the pathogenesis of eosinophilic esophagitis, as well as the methods of its diagnosis, treatment and prevention, are still at the stage of their deep study and improvement. The issue of eosinophilic esophagitis should be considered as an interdisciplinary one, since it involves the interaction of a pediatrician and/or therapist, allergist, gastroenterologist, nutritionist, endoscopist, and pathomorphologist.
DIAGNOSTIC ACCURACY OF COLOR ANDPULSED DOPPLER IN THE EVALUATION OF PAROTID GLAND TUMORS
Authors: Zareen Zulfiqar  , Nawaz Rashid  , Dogar Iqbal Hussain , Fareeha Nawaz  , Mahjabeen Tariq  , Saulat Sarfraz  
Published: November 2021

Background: The parotid glands are the largest salivary glands in humans and are frequently involved in various primary & systemic disease processes. The most common benign parotid gland tumor is pleomorphic adenoma. Around 20% of parotid tumors are malignant with most common parotid tumors being mucoepidermoid carcinoma and adenoid cystic carcinoma.
Objective:
To determine the diagnostic accuracy of pulsed and color Doppler for the evaluation of parotid gland cancer.
Methods:
It was a cross sectional study by design carried out in Department of Radiology and Department of Maxillofacial Surgery, Mayo Hospital – Lahore in a duration of three year. All the patients were examined with mind-ray 7.5 MHz linear transducer.
There are three methods used collectively; Grey Scale, color Doppler and Pulsed Doppler in sonographic examination. Color Doppler and pulsed Doppler demonstrate number of blood vessels within the tumor, their Peak Systolic Velocity and Resistive Index respectively.
Histo-pathological results were correlated post operatively with the data obtained from Doppler ultrasound. Data was analyzed using SPSS 23.0
Results:
In this study, 192 patients were included .The mean age was 39.42 ± 11.93 years. 58.85% (112) were male patients and 41.15 %( 80) patients were females. The solid masses with regular margins were evaluated and the diagnostic accuracy of pulsed Doppler was found to be 87.5% taking histopathology as gold standard.
Conclusion:
This study shows pulsed Doppler to be more accurate tool for diagnosis of parotid gland tumor as compared to color Doppler taking histopathology as gold standard.
CORRELATION OF THROMBOCYTOPENIA WITH GRADING OF ESOPHAGEAL VARICES IN PATIENTS WITH CIRRHOSIS
Authors: Samia Kausar  , Kiran Fatima  , Zunera Jahanzeb  , Muhammad Farooq  
Published: November 2021

Abstract
Objective: To determine the relationship of severity of thrombocytopenia with various grades of esophageal varices in patients with cirrhosis.
Study design: A cross sectional observational study.
Place and duration of study: Medicine department of Pakistan Railway General Hospital from 1st September, 2018 to 31st August, 2020.
Material and Methods: The record of 100 patients with cirrhosis having concomitant thrombocytopenia and esophageal varices was retrospectively analyzed. The information about clinical, hematological, biochemical, ultrasound and endoscopic findings was retrieved from medical record. On the basis of platelet count, four groups were made. Group I consisted of patients with a platelet count ≤ 20,000/ µl, group II 21,000-49,000/ µl, group III 50,000-99,000/ µl, and group IV 100,000- 149,000/ µl. Esophageal varices were reclassified as small and large varices group depending on the size. Correlation of thrombocytopenia with grading of esophageal varices was calculated using spearman’s correlation.
Results: Out of 100 patients, 76% had large varices and 24% had small varices. Thrombocytopenia was more severe in patients with large varices group when compared with small varices group. There was significant negative correlation between thrombocytopenia and grading of esophageal varices (r= -.691; P < 0.001).
Conclusion: The severity of thrombocytopenia increased with increase in the size of esophageal varices. Low platelet count can strongly predict large varices in patients with cirrhosis.
CONTRIBUIÇÃO DA PANDEMIA DE COVID-19 PARA O AUMENTO DOS CASOS DE SÍNDROME DE BURNOUT EM PROFISSIONAIS DE ENFERMAGEM
Authors: Marcos Natália Duarte , Ribeiro Tiago Pacheco Brandão 
Published: November 2021

O presente estudo surge a partir da necessidade de investigar a saúde mental dos profissionais de enfermagem diante o enfrentamento da COVID-19, objetivando caracterizar o esgotamento profissional e identificar as características envolvidas no trabalho da enfermagem na linha de frente do combate à pandemia que possam influenciar na ocorrência da Síndrome de Burnout. A presente pesquisa constata que sintomas de depressão, ansiedade e estresse têm sido frequentes entre esses trabalhadores, logo, promover a saúde dos profissionais é um assunto de extrema relevância, uma vez que estes indivíduos precisam estar bem para serem capazes de prestar um serviço de qualidade à população. É necessário implementar medidas de intervenção psicológica, tais como: reorganização da jornada de trabalho (permitindo tempo para descanso); valorização e reconhecimento pelo serviço prestado; melhora na remuneração; fornecimento adequado de EPIs e auxílio psicológico para promover o bem-estar mental e uma melhor qualidade de vida aos profissionais de saúde expostos durante a pandemia. Conclui-se que é de suma importância explorar as possíveis formas de se evitar o Burnout, uma vez que o enfermeiro é um profissional de fundamental importância para o combate ao novo coronavírus.
ANALISIS WAKTU PEMANASAN DAN RASIO KOMPOSISI VOLUME KEROSEN DAN MINYAK PELUMAS PADA PROSES UPGRADING BROWN COAL (UBC) TERHADAP NILAI KALOR BATUBARA
Authors: Lowinsky Monica , Tunggal Abdi , Aswan Arizal , Junaidi Robert , Zurohaina Zurohaina 
Published: November 2021

Pada proses upgrading brown coal, kadar air pada batubara peringkat rendah dihilangkan dengan pemanasan dalam media minyak yang bahan utamanya adalah minyak ringan dan minyak berat. Pada variasi waktu proses menggunakan rasio 1:1:0,5 pada 1 kg batubara ukuran 20 mesh, 1 liter minyak tanah dan 5 ml minyak pelumas kemudian dipanaskan dengan temperatur sebesar 200 C pada tekanan 3 bar dengan memvariasikan waktu pemanasan 1,5 jam, 2 jam, 2,5 jam, 3 jam. Pada rasio perbandingan komposisi, digunakan perbandingan 1:1 yaitu 1 kg batubara ukuran 60 mesh dan 1 liter minyak tanah dengan variasi minyak pelumas sebesar 0,5%, 1 %, 1,5 %, 2 % dan 2,5 % berat batubara. Penelitian ini bertujuan untuk mengetahui perbandingan komposisi volume minyak tanah dan minyak pelumas yang paling optimal pada proses UBC ini. Berdasarkan hasil analisa sebelum dilakukan UBC diketahui bahwa kadar air dari sampel batubara sebesar 19,58% dan nilai kalor sebesar 3814,7810 Cal/gr kemudian setelah dilakukan proses UBC maka didapatkan peningkatan nilai kalor yang cukup signifikan, pada variasi waktu kadar air berkurang hingga 14,27 dan nilai kalor 7271,1655 terjadi pada waktu pemanasan 3 jam, pada variasi perbandingan komposisi terjadi penurunan kadar air sebesar 8,98 % dan nilai kalor 7479,0601 Cal/gr terjadi pada rasio 1:1:2,5 %.

Kata kunci: Batubara Lignit, Kadar Air, Nilai Kalor, UBC
Analisis Karakteristik Pulp Campuran Tandan Kosong Kelapa Sawit dan Pelepah Pisang dengan Pelarut NaOH
Authors: Rizky Amelia Sari , Yerizam Muhammad , Dewi Erwana 
Published: November 2021

Tandan kosong kelapa sawit (TKKS) merupakan limbah padatan yang dihasilkan dari proses pembuatan minyak kelapa sawit yang selulosa (45,95%), kadar abu (1,23%), hemiselulosa (22,84%), kadar air (3,74%) dan lignin (16,49%). Pelepah pisang mempunyai kandungan selulosa yang tinggi akan tetapi belum dimanfaatkan secara optimal yang memiliki kandungan densitas ( 1,35 gr/cm3), selulosa (63 -64 %), hemiselulosa (20 %), lignin (5%), kekuatan Tarik rata-rata (600 Mpa), modulus tarik rata-rata (17,85 Gpa), pertambahan panjang (3,36 %), diameter serat (5,8 µm), serta panjang serat (30,9240 cm). Namun bahan-bahan ini mempunyai karakteristik dan sifat fisika kimia yang berbeda-beda. Karakteristik menjadikan perlunya analisa agar menghasilkan pulp yang diinginkan berada pada kondisi optimal. Beberapa parameter yang diukur di antaranya, konsentrasi larutan NaOH dengan variasi 7% dan 9%, dengan variasi bahan baku 40-60% serta waktu pemasakan dengan variasi waktu 75, 90, 105, 120 dan 135 menit. Sehingga pada penelitian ini didapatkan kondisi optimumnya yakni pada rasio 40:60, dengan konsentrasi 9% dan waktu pemasakan selama 120 menit didapatkan nilai kadar lignin 11,21% dan kadar selulosa 68,94%.
Oil palm empty fruit bunches or TKKS are solid wastes produced from the process of making palm oil which are cellulose (45.95%), ash content (1.23%), hemicellulose (22.84%), water content (3.74 %) and lignin (16.49%). Banana midrib has a high cellulose content but has not been used optimally which contains density (1.35 g/cm3), cellulose (63 -64 %), hemicellulose (20 %), lignin (5%), average tensile strength. average (600 Mpa), average tensile modulus (17.85 Gpa), increase in length (3.36%), fiber diameter (5.8 m), and fiber length (30,9240 cm). However, these materials have different physicochemical characteristics and properties. The characteristics make the need for analysis in order to produce the desired pulp in optimal conditions. Several parameters were measured including the concentration of NaOH solution with variations of 7% and 9%, with variations of raw materials 40-60% and cooking time with variations of 75, 90, 105, 120 and 135 minutes. So that in this study the optimum conditions were obtained, namely at a ratio of 40:60, with a concentration of 9% and cooking time for 120 minutes, the lignin content was 11.21% and the cellulose content was 68.94%.
خصائص قراءة أبي جعفر المدني من طريق الدُّرَّة المضيَّة جمعاً ودراسةً
Authors: توم حامد علي بشارة د. محمَّد 
Published: November 2021

Abstract:
This research aims to collect characteristics of Abu Jafaar Almadani version of reciting , specifying its originality and chapters, clarifying the way it was reciting ,mentioning each witnesses specified at Aldura Almadiyah version to Ibn Aljazri and opening the door for subsequent studies concerning the characteristics of Abu Jafaar Almadani version of reciting .The research has been divided to introduction which includes the subject of the research , its problem, enquiries , objectives, importance , reason behind determining such research and the previous studies; the research, moreover, tackles the approach set and preface in Abu Jafaar Almadani personal life in addition to its symbol and narrators.The researcher in successive four chapters discussed the fundamentals and reciting of Abu Jafaar Almadani dividing the Holy Quran into three chapters (categories ) and concluding with recommendations and scientific referencing.
Adenosine-induced ventricular fibrillation in a patient with supraventricular tachycardia
Authors: Lee Shu Yu , Pothiawala Sohil , Meng Seet Chong 
Published: November 2021

Adenosine is frequently used for paroxysmal supraventricular tachycardia (PSVT) treatment in the emergency department (ED). Atrial and ventricular pro-arrhythmic effects of adenosine were described in the literature, but ventricular fibrillation (VF) secondary to adenosine administration was rarely reported (with an incidence of < 1%). Reported herein is the first case of a 72-year-old female patient who developed VF hemodynamic collapse after an intravenous administration of adenosine for PSVT treatment. She had no known pre-excitation or accessory pathway, nor any underlying structural heart disease or prolonged QT syndrome. Raising awareness of this potential life-threatening pro-arrhythmic effect of adenosine is important, given its frequent use for PSVT treatment in the ED.
Overview of E-Cigarette (Vape) Usage Behavior in 2021 UMJ FKM Students
Authors: Oktavia Ega , Fitri Azizah Alika , Shafira Zaintira Baby , Surya Carlina 
Published: November 2021

E-cigarettes were first created in a modern way by a pharmacist from China in 2003 and patented in 2004 and then began to spread throughout the world. The results of a survey conducted by the International Tobacco Control Survey in America, Canada, Australia, and England, currently 29% of former smokers use electronic cigarettes, 7.6% have tried using electronic cigarettes and 46.6% are aware of the existence of electronic cigarettes. Some conditions that can arise from long-term use of nicotine are increased blood pressure and heart rate, as well as an increased risk of developing insulin resistance, type 2 diabetes, and heart disease. This research uses a qualitative approach with a descriptive method. Based on in-depth interviews with the informants, it was found that the informants had various reasons for using vapor, both for health reasons and for environmental reasons. All resource persons also argue that the dominant factor that makes a person use vapor is environmental factors. Meanwhile, when viewed from the behavior of all informants, they do not use vapor continuously but at certain times, even one of the informants still uses conventional cigarettes to be accompanied by vapor.
Self Esteem in Adolescent Smokers at South Tangerang in 2021
Authors: Annisa Ina , Ismi Hanifah , Khairunnisa Khairunnisa , Rizarni Lingga , Fauziah Munaya 
Published: November 2021

Smoking behavior is an activity where someone uses cigarettes. One of the factors that influence smoking habits in adolescents is to increase self-esteem. The purpose of this study was to obtain information about self-esteem in adolescent smokers at South Tangerang in 2021. The research method is descriptive using a qualitative study design. The sample in this study were four adolescent active smokers with an age range of 19 – 23 years who came from different universities by conducting in-depth interviews and conducting document reviews. This interview transcript was evaluated using content analysis, namely a one-by-one analysis of the pure interview results. The results of the interview showed that the informant felt the physical influence or the symptoms felt, namely coughing and enjoyed. Informants do not consider smoking behavior to increase self-confidence, but relationships and interactions in the family are considered the most valuable, valuable, and important for the development of individuals as members. Smoking can be a way for teenagers to look free and mature when they adjust to their smoking peers even though smoking can encourage the emergence of diseases that can lead to death. Based on this, it can be concluded that smoking behavior does not affect a person's level of self-confidence (self-esteem). Smoking can also encourage the emergence of types of diseases that can lead to death because smoking will release about 4,000 chemical components which not only affect active smokers but also those around them who feel the dangers of passive smokers.