bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proposing a new solution for marine debris by utilizing on-board low-temperature eco-friendly pulverization system
Authors: Lee Dong-Ha , Park Sungkyun , Kim Hee-Tae , Kim Jeong-Dae , Kim Jeong-Hyeon , Kim Seul-Kee , Seo Jung-Kwan , Song Pung-Keun , Oh Jeong-Eun , Youn BuHyun , Choi Gyung-Min , Lim Dong-Ha , Lee Jae-Myung 
Published: December 2021

AbstractDeveloping an effective and efficient recycling process for marine debris (MD) is one of the most urgent issues to maintain environmental sustainability on Earth. However, restricted storage capacities and secondary pollution (e.g., microbial adhesion, putrefaction) limit the proper MD recycling. Here, we proposed a complete eco-friendly low-temperature MD pulverizing system that utilizes excessive liquefied natural gas (LNG) cold energy (LCE) in an LNG propulsion ship to improve the efficiency and effectiveness of MD recycling. The prototype design of the low-temperature pulverization (LTP) system showed that consumable refrigerant (liquid nitrogen) up to 2831 kg per hour could be substituted. Furthermore, with a 20% ship output, 1250 kg of MD could be treated with 363 kg of additional refrigerant. In addition, LTP systems utilizing LCE could increase the storage capacity by more than 10 times compared to bulk MD while minimizing the required energy consumption. To determine the feasibility of LTP for MD recycling, four types of plastics obtained from actual MD from a coastal area in Busan, Korea were classified and tested.
Near infrared photothermoelectric effect in transparent AZO/ITO/Ag/ITO thin films
Authors: Bianchi C. , Marques A. C. , da Silva R. C. , Calmeiro T. , Ferreira I. 
Published: December 2021

AbstractA new concept of oxide-metal-oxide structures that combine photothermoelectric effect with high reflectance (~ 80%) at wavelengths in the infrared (> 1100 nm) and high transmittance in the visible range is reported here. This was observed in optimized ITO/Ag/ITO structure, 20 nm of Silver (Ag) and 40 nm of Indium Tin Oxide (ITO), deposited on Aluminum doped Zinc Oxide (AZO) thin film. These layers show high energy saving efficiency by keeping the temperature constant inside a glazed compartment under solar radiation, but additionally they also show a photothermoelectric effect. Under uniform heating of the sample a thermoelectric effect is observed (S = 40 mV/K), but when irradiated, a potential proportional to the intensity of the radiation is also observed. Therefore, in addition to thermal control in windows, these low emission coatings can be applied as transparent photothermoelectric devices.
Durable nanocomposite face masks with high particulate filtration and rapid inactivation of coronaviruses
Authors: Gonzalez Andrew , Aboubakr Hamada A. , Brockgreitens John , Hao Weixing , Wang Yang , Goyal Sagar M. , Abbas Abdennour 
Published: December 2021

AbstractThe COVID-19 pandemic presents a unique challenge to the healthcare community due to the high infectivity rate and need for effective personal protective equipment. Zinc oxide nanoparticles have shown promising antimicrobial properties and are recognized as a safe additive in many food and cosmetic products. This work presents a novel nanocomposite synthesis approach, which allows zinc oxide nanoparticles to be grown within textile and face mask materials, including melt-blown polypropylene and nylon-cotton. The resulting nanocomposite achieves greater than 3 log10 reduction (≥ 99.9%) in coronavirus titer within a contact time of 10 min, by disintegrating the viral envelope. The new nanocomposite textile retains activity even after 100 laundry cycles and has been dermatologist tested as non-irritant and hypoallergenic. Various face mask designs were tested to improve filtration efficiency and breathability while offering antiviral protection, with Claros’ design reporting higher filtration efficiency than surgical masks (> 50%) for particles ranged 200 nm to 5 µm in size.
Health-related quality of life and insulin resistance over a 10-year follow-up
Authors: Kazukauskiene Nijole , Podlipskyte Aurelija , Varoneckas Giedrius , Mickuviene Narseta 
Published: December 2021

AbstractThe aim of the study was to investigate the association between insulin resistance (IR) and health-related quality of life (HRQoL) among citizens of Palanga in a 10-year follow-up. A randomized epidemiological study was performed with 835 subjects. The following data were examined using questionnaires: sociodemographic characteristics, behavioural factors, HRQoL and self-perceived health. Fasting blood samples were drawn from all participants, and biochemical tests were performed for glucose and insulin. IR was evaluated by the homeostasis model assessment of IR (HOMA-IR). In subjects with IR, after adjusting for various factors, logistic regression analysis showed that within 10 years, there was a significantly higher chance of deteriorating HRQoL in the areas of physical functioning (odds ratio [OR] = 1.15, p < 0.001), emotional role limitations (OR = 1.07, p = 0.034), social functioning (OR = 1.26, p = 0.004), pain (OR = 1.09, p = 0.005) and general health perception (OR = 1.07, p = 0.022). People with IR have a worse HRQoL, and as they age, they are significantly more likely to have a deterioration in their HRQoL than people without IR in the areas of physical functioning, emotional role limitations, social functioning, pain and general health perception.
Highlighting the impact of social relationships on the propagation of respiratory viruses using percolation theory
Authors: Mathiot Jean-François , Gerbaud Laurent , Breton Vincent 
Published: December 2021

AbstractWe develop a site-bond percolation model, called PERCOVID, in order to describe the time evolution of all epidemics propagating through respiratory tract or by skin contacts in human populations. This model is based on a network of social relationships representing interconnected households experiencing governmental non-pharmaceutical interventions. As a very first testing ground, we apply our model to the understanding of the dynamics of the COVID-19 pandemic in France from December 2019 up to December 2021. Our model shows the impact of lockdowns and curfews, as well as the influence of the progressive vaccination campaign in order to keep COVID-19 pandemic under the percolation threshold. We illustrate the role played by social interactions by comparing two typical scenarios with low or high strengths of social relationships as compared to France during the first wave in March 2020. We investigate finally the role played by the α and δ variants in the evolution of the epidemic in France till autumn 2021, paying particular attention to the essential role played by the vaccination. Our model predicts that the rise of the epidemic observed in July and August 2021 would not result in a new major epidemic wave in France.
Morphological features of single cells enable accurate automated classification of cancer from non-cancer cell lines
Authors: Mousavikhamene Zeynab , Sykora Daniel J. , Mrksich Milan , Bagheri Neda 
Published: December 2021

AbstractAccurate cancer detection and diagnosis is of utmost importance for reliable drug-response prediction. Successful cancer characterization relies on both genetic analysis and histological scans from tumor biopsies. It is known that the cytoskeleton is significantly altered in cancer, as cellular structure dynamically remodels to promote proliferation, migration, and metastasis. We exploited these structural differences with supervised feature extraction methods to introduce an algorithm that could distinguish cancer from non-cancer cells presented in high-resolution, single cell images. In this paper, we successfully identified the features with the most discriminatory power to successfully predict cell type with as few as 100 cells per cell line. This trait overcomes a key barrier of machine learning methodologies: insufficient data. Furthermore, normalizing cell shape via microcontact printing on self-assembled monolayers enabled better discrimination of cell lines with difficult-to-distinguish phenotypes. Classification accuracy remained robust as we tested dissimilar cell lines across various tissue origins, which supports the generalizability of our algorithm.
Believers in pseudoscience present lower evidential criteria
Authors: Rodríguez-Ferreiro Javier , Barberia Itxaso 
Published: December 2021

AbstractPrevious studies have proposed that low evidential criteria or proneness to jump to conclusions influences the formation of paranormal beliefs. We investigated whether the low evidential criteria hypothesis for paranormal beliefs extends to a conceptually distinct type of unwarranted beliefs: those related to pseudoscience. We presented individuals varying in their endorsement of pseudoscientific beliefs with two hypothesis testing tasks. In the beads task, the participants were asked to decide from which of two jars containing different proportions of colored beads they were collecting samples. In the mouse trap task, they were asked to guess which rule determined whether a participant-controlled mouse obtained a piece of cheese or was trapped. In both cases, the volunteers were free to decide when to stop collecting evidence before completing the tasks. Our results indicate that, compared to skeptics, individuals presenting stronger endorsement of pseudoscientific beliefs tend to require less evidence before coming to a conclusion in hypothesis testing situations.
The relationship between objective app engagement and medication adherence in asthma and COPD: a retrospective analysis
Authors: Kaye Leanne , Gondalia Rahul , Thompson Alesha , Stempel David A. , Barrett Meredith A. 
Published: December 2021

AbstractDigital health tools can promote disease self-management, but the association of smartphone app engagement and medication adherence is unclear. We assessed the relationship between objective smartphone app engagement and controller medication use in adults with asthma and COPD. We retrospectively analyzed data from participants enrolled in a digital self-management platform for asthma and COPD. Eligible adults had a smartphone and a paired electronic medication monitor (EMM). Longitudinal, mixed-effects logistic regressions estimated the relationship between daily app engagement (app opens, session duration) and daily controller medication use. Data from 2309 participants (71% asthma; 29% COPD) was analyzed. Opening the app (vs. not opening the app) was associated with significantly greater odds (OR (95% CI)) of using controller medications in asthma (2.08 (1.98, 2.19)) and COPD (1.61 (1.49, 1.75). Longer session duration was also associated with greater odds of using controller medications in asthma and COPD, but the odds of use attenuated with longer session duration in COPD. This study presents a novel assessment of the relationship between objectively-measured smartphone app engagement and controller medication use in asthma and COPD. Such insights may help develop targeted digital health tools and interventions.
The impact of carbon source on cell growth and the production of bioactive compounds in cell suspensions of Hancornia speciosa Gomes
Authors: Dantas Luciana Arantes , Faria Paula Sperotto Alberto , Dário Bruno Matheus Mendes , Arantes Ana Luíza Martins , Silva Fabiano Guimarães , Avila Roniel Geraldo , Pereira Paulo Sérgio , Neto Aurélio Rubio 
Published: December 2021

AbstractBelonging to the Brazilian flora, the species Hancornia speciosa (Gomes), known as mangabeira, has bioactive compounds of interest, such as flavonoids, xanthones, and proanthocyanidins. The objective of this study was to determine how the supplementation of sugars in culture medium affects the osmotic potential of the medium, as well as its influence on cell growth and on the concentration of phenolic compounds. For this purpose, after 90 days of subculture, 20 mL aliquots of the cultures were added to flasks containing 20 mL of medium with different sugars (glucose, fructose, sucrose, mannitol, and sorbitol) under a 16-h photoperiod with a spectral range between 400 and 700 nm of photosynthetically active radiation (45–55 μmol m−2 s−1) in a shaker at 110 rpm. After 30 days, the pH, electrical conductivity, osmotic potential, biomass accumulation, and concentrations of phenolic compounds were evaluated. Regardless of their concentration in the medium, the sugars sorbitol and mannitol provided more unfavorable conditions for water absorption at the cellular level, reducing the water potential of the medium. Sucrose favored greater water absorption and biomass accumulation. Among the various sugar concentrations, 3% (30 g/L) sucrose or glucose improved the accumulation of fresh and dry cell weight and the production of polyphenols such as chlorogenic acid, epicatechin, rosmarinic acid, hesperidin, rutin, and quercetin. In addition, they resulted in a higher osmotic potential of the medium and larger cells than other carbon sources. Despite the differences in cell size, no culture conditions compromised cell survival.
Satisfied quantitative value can be acquired by short-time bone SPECT/CT using a whole-body cadmium–zinc–telluride gamma camera
Authors: Yamane Tomohiko , Takahashi Masafumi , Matsusaka Yohji , Fukushima Kenji , Seto Akira , Kuji Ichiei , Matsunari Ichiro 
Published: December 2021

AbstractThe aim of this study was to evaluate the quantitative values of short-time scan (STS) of metastatic lesions compared with a standard scan (SS) when acquired by whole-body bone SPECT/CT with cadmium–zinc–telluride (CZT) detectors. We retrospectively reviewed 13 patients with bone metastases from prostate cancer, who underwent SPECT/CT performed on whole-body CZT gamma cameras. STSs were obtained using 75, 50, 25, 10, and 5% of the list-mode data for SS, respectively. Regions of interest (ROIs) were set on the increased uptake areas diagnosed as metastases. Intraclass correlation coefficients (ICCs) of standardized uptake values (SUVs) for the ROIs were calculated between the SS and each STS, and ICC ≥ 0.8 was set as a perfect correlation. Moreover, the repeatability coefficient (RC) was calculated, and RC ≤ 20% was defined as acceptable. A total of 152 metastatic lesions were included in the analysis. The ICCs between the SS vs. 75%-STS, 50%-STS, 25%-STS, 10%-STS, and 5%-STS were 0.999, 0.997, 0.994, 0.983, and 0.955, respectively. The RCs of the SS vs. 75%-STS, 50%-STS, 25%-STS, 10%-STS, and 5%-STS were 7.9, 12.4, 19.8, 30.8, and 41.3%, respectively. When evaluating the quality of CZT bone SPECT/CT acquired by a standard protocol, 25%-STS may provide adequate quantitative values.
Photoelectroactive artificial synapse and its application to biosignal pattern recognition
Authors: Oh Seyong , Lee Je-Jun , Seo Seunghwan , Yoo Gwangwe , Park Jin-Hong 
Published: December 2021

AbstractIn recent years, optoelectronic artificial synapses have garnered a great deal of research attention owing to their multifunctionality to process optical input signals or to update their weights optically. However, for most optoelectronic synapses, the use of optical stimuli is restricted to an excitatory spike pulse, which majorly limits their application to hardware neural networks. Here, we report a unique weight-update operation in a photoelectroactive synapse; the synaptic weight can be both potentiated and depressed using “optical spikes.” This unique bidirectional operation originates from the ionization and neutralization of inherent defects in hexagonal-boron nitride by co-stimuli consisting of optical and electrical spikes. The proposed synapse device exhibits (i) outstanding analog memory characteristics, such as high accessibility (cycle-to-cycle variation of <1%) and long retention (>21 days), and (ii) excellent synaptic dynamics, such as a high dynamic range (>384) and modest asymmetricity (<3.9). Such remarkable characteristics enable a maximum accuracy of 96.1% to be achieved during the training and inference simulation for human electrocardiogram patterns.
Iron-rich talc as air-stable platform for magnetic two-dimensional materials
Authors: Matković Aleksandar , Ludescher Lukas , Peil Oleg E. , Sharma Apoorva , Gradwohl Kevin-P. , Kratzer Markus , Zimmermann Maik , Genser Jakob , Knez Daniel , Fisslthaler Evelin , Gammer Christoph , Lugstein Alois , Bakker Ronald J. , Romaner Lorenz , Zahn Dietrich R. T. , Hofer Ferdinand , Salvan Georgeta , Raith Johann G. , Teichert Christian 
Published: December 2021

AbstractIntrinsically magnetic layered materials – especially monolayers – suffer from the lack of ambient stability and mostly exhibit magnetic ordering only at cryogenic temperatures. These restrains impose a great challenge for the integration of two-dimensional magnetic materials into future technologies. We propose to overcome this by exploiting phyllosilicates, such as iron-rich talc. Via combined magnetic force microscopy in applied external magnetic fields, superconducting quantum interference device magnetometry, first-principle calculations, and structural analysis, we demonstrate that incorporated iron ions in talc are in a very robust high spin state, resulting in a weak ferromagnetic behavior at room temperature. Iron-rich talc can be thinned down to a monolayer, remaining fully stable under ambient conditions, and retaining magnetic properties even in monolayers. Finally, we propose iron-rich end members of the phyllosilicates as very promising platforms for air-stable magnetic monolayers.
Predicting changes in glycemic control among adults with prediabetes from activity patterns collected by wearable devices
Authors: Patel Mitesh S. , Polsky Daniel , Small Dylan S. , Park Sae-Hwan , Evans Chalanda N. , Harrington Tory , Djaraher Rachel , Changolkar Sujatha , Snider Christopher K. , Volpp Kevin G. 
Published: December 2021

AbstractThe use of wearables is increasing and data from these devices could improve the prediction of changes in glycemic control. We conducted a randomized trial with adults with prediabetes who were given either a waist-worn or wrist-worn wearable to track activity patterns. We collected baseline information on demographics, medical history, and laboratory testing. We tested three models that predicted changes in hemoglobin A1c that were continuous, improved glycemic control by 5% or worsened glycemic control by 5%. Consistently in all three models, prediction improved when (a) machine learning was used vs. traditional regression, with ensemble methods performing the best; (b) baseline information with wearable data was used vs. baseline information alone; and (c) wrist-worn wearables were used vs. waist-worn wearables. These findings indicate that models can accurately identify changes in glycemic control among prediabetic adults, and this could be used to better allocate resources and target interventions to prevent progression to diabetes.
Rats exhibit age-related mosaic loss of chromosome Y
Authors: Orta Alberto H. , Bush Stephen J. , Gutiérrez-Mariscal Mariana , Castro-Obregón Susana , Jaimes-Hoy Lorraine , Grande Ricardo , Vázquez Gloria , Gorostieta-Salas Elisa , Martínez-Pacheco Mónica , Díaz-Barba Karina , Cornejo-Páramo Paola , Sanchez-Flores Alejandro , Székely Tamas , Urrutia Araxi O. , Cortez Diego 
Published: December 2021

AbstractMosaic loss of the Y chromosome (LOY) is the most frequent chromosomal aberration in aging men and is strongly correlated with mortality and disease. To date, studies of LOY have only been performed in humans, and so it is unclear whether LOY is a natural consequence of our relatively long lifespan or due to exposure to human-specific external stressors. Here, we explored whether LOY could be detected in rats. We applied a locus-specific PCR and target sequencing approach that we used as a proxy to estimate LOY in 339 samples covering eleven tissues from young and old individuals. We detected LOY in four tissues of older rats. To confirm the results from the PCR screening, we re-sequenced 60 full genomes from old rats, which revealed that the Y chromosome is the sole chromosome with low copy numbers. Finally, our results suggest that LOY is associated with other structural aberrations on the Y chromosome and possibly linked to the mosaic loss of the X chromosome. This is the first report, to our knowledge, demonstrating that the patterns of LOY observed in aging men are also present in a rodent, and conclude that LOY may be a natural process in placental mammals.
Cryptogamic organisms are a substantial source and sink for volatile organic compounds in the Amazon region
Authors: Edtbauer Achim , Pfannerstill Eva Y. , Pires Florentino Ana Paula , Barbosa Cybelli G. G. , Rodriguez-Caballero Emilio , Zannoni Nora , Alves Rodrigo P. , Wolff Stefan , Tsokankunku Anywhere , Aptroot André , de Oliveira Sá Marta , de Araújo Alessandro C. , Sörgel Matthias , de Oliveira Sylvia Mota , Weber Bettina , Williams Jonathan 
Published: December 2021

AbstractCryptogamic organisms such as bryophytes and lichens cover most surfaces within tropical forests, yet their impact on the emission of biogenic volatile organic compounds is unknown. These compounds can strongly influence atmospheric oxidant levels as well as secondary organic aerosol concentrations, and forest canopy leaves have been considered the dominant source of these emissions. Here we present cuvette flux measurements, made in the Amazon rainforest between 2016–2018, and show that common bryophytes emit large quantities of highly reactive sesquiterpenoids and that widespread lichens strongly uptake atmospheric oxidation products. A spatial upscaling approach revealed that cryptogamic organisms emit sesquiterpenoids in quantities comparable to current canopy attributed estimates, and take up atmospheric oxidation products at rates comparable to hydroxyl radical chemistry. We conclude that cryptogamic organisms play an important and hitherto overlooked role in atmospheric chemistry above and within tropical rainforests.
A Nd6 molecular butterfly: a unique all-in-one material for SMM, MCE and maiden photosensitized opto-electronic device fabrication
Authors: Das Krishna Sundar , Saha Sayan , Pal Baishakhi , Adhikary Amit , Moorthy Shruti , Bala Sukhen , Akhtar Sohel , Ghose Pradeepta Kumar , Singh Saurabh Kumar , Ray Partha Pratim , Mondal Raju 
Published: December 2021

We report herein an aesthetically pleasing hexanuclear Nd6 molecular butterfly using a rather nonconventional N-rich pyridyl-pyrazolyl based ligand and their concomitant SMM and MCE properties along with elusive electronic properties.