bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does Cash Transfer Promote Market Citizenship?
Authors: Ark-Yıldırım Ceren , Smyrl Marc 
Published: May 2021

AbstractThe most obvious conclusion of this book is that there is no single Turkish experience. Nor can we reach definitive once-and-for-all conclusions about the impact of CT as an instrument of social assistance. Comparison among our cases highlights variables grounded in local conditions and policy design that help determine the outcome of CT projects, and whose relevance extends far beyond Turkey. Among these are human and financial resources, but also of the capacity for local knowledge. When these allow consistent and appropriate targeting, CT can provide an important step in the direction of inclusion and equality in a market context. It would be misleading, however, to believe that this instrument on its own is sufficient. At the core of market citizenship is the dignity conferred not only by paying one’s own way, but also by earning one’s own way: CT instruments work best as a complement to, not replacement for, access to the official labor market.
Dark scalars and heavy neutral leptons at DarkQuest
Authors: Batell Brian , Evans Jared A. , Gori Stefania , Rai Mudit 
Published: May 2021

AbstractThe proposed DarkQuest beam dump experiment, a modest upgrade to the existing SeaQuest/SpinQuest experiment, has great potential for uncovering new physics within a dark sector. We explore both the near-term and long-term prospects for observing two distinct, highly-motivated hidden sector benchmark models: heavy neutral leptons and Higgs-mixed scalars. We comprehensively examine the particle production and detector acceptance at DarkQuest, including an updated treatment of meson production, and light scalar production through both bremsstrahlung and gluon-gluon fusion. In both benchmark models, DarkQuest will provide an opportunity to probe previously inaccessible interesting regions of parameter space on a fairly short timescale when compared to other proposed experiments.
Cutibacterium modestum and “Propionibacterium humerusii” represent the same species that is commonly misidentified as Cutibacterium acnes
Authors: Goldenberger Daniel , Søgaard Kirstine K. , Cuénod Aline , Seth-Smith Helena , de Menezes Daniel , Vandamme Peter , Egli Adrian 
Published: May 2021

AbstractCutibacterium spp. play an increasing role in soft tissue and implant-associated infections. We isolated a novel Cutibacterium spp. from an implant and investigated this isolate using multiple identification approaches. Correct identification was hampered by inconsistent reference data. The isolate was characterised using conventional methods such as Gram stain, MALDI-TOF MS, and antimicrobial susceptibility testing against multiple antimicrobials. Partial 16S rRNA gene sequencing and whole genome sequencing were also performed. In addition, we summarised the available published sequence data and compared prior data to our strain. Conventional phenotypic identification of our isolate resulted in Cutibacterium spp. After analysis of 16S rRNA gene and genome sequences, our isolate was identified as C. modestum, a very recently described species. The 16S rRNA gene analysis was hampered by three incorrect nucleotides within the 16S rRNA gene reference sequence of C. modestum M12T (accession no. LC466959). We also clearly demonstrate that this novel species is identical to tentatively named “Propionibacterium humerusii”. Retrospective data analysis indicates that C. modestum is a clinically important Cutibacterium species often misidentified as C. acnes. The isolation and identification of Cutibacterium spp. is still a challenge. The correct description of very recently named C. modestum and the availability of a correct 16S rRNA sequence of the type strain may help to clarify the taxonomical uncertainty concerning “P. humerusii”. The novel C. modestum is an additional, clinically important species within the genus Cutibacterium and may represent a new member of the human skin microbiome.
Effects of surface impedance on current density in a piezoelectric resonator for impedance distribution sensing
Authors: Liu Jing , Du Jianke , Wang Ji , Yang Jiashi 
Published: May 2021

AbstractWe study the relationship between the surface mechanical load represented by distributed acoustic impedance and the current density distribution in a shear mode piezoelectric plate acoustic wave resonator. A theoretical analysis based on the theory of piezoelectricity and trigonometric series is performed. In the specific and basic case when the surface load is due to a local mass layer, numerical results show that the current density concentrates under the mass layer and is sensitive to the physical as well as geometric parameters of the mass layer such as its location and size. This provides the theoretical foundation for predicting the surface impedance pattern from the current density distribution, which is fundamental to the relevant acoustic wave sensors.
Complex response analysis of a non-smooth oscillator under harmonic and random excitations
Authors: Ma Shichao , Ning Xin , Wang Liang , Jia Wantao , Xu Wei 
Published: May 2021

AbstractIt is well-known that practical vibro-impact systems are often influenced by random perturbations and external excitation forces, making it challenging to carry out the research of this category of complex systems with non-smooth characteristics. To address this problem, by adequately utilizing the stochastic response analysis approach and performing the stochastic response for the considered non-smooth system with the external excitation force and white noise excitation, a modified conducting process has proposed. Taking the multiple nonlinear parameters, the non-smooth parameters, and the external excitation frequency into consideration, the steady-state stochastic P-bifurcation phenomena of an elastic impact oscillator are discussed. It can be found that the system parameters can make the system stability topology change. The effectiveness of the proposed method is verified and demonstrated by the Monte Carlo (MC) simulation. Consequently, the conclusions show that the process can be applied to stochastic non-autonomous and non-smooth systems.
Complex community responses underpin biodiversity change following invasion
Authors: Kortz Alessandra R. , Magurran Anne E. 
Published: May 2021

AbstractHow do invasive species change native biodiversity? One reason why this long-standing question remains challenging to answer could be because the main focus of the invasion literature has been on shifts in species richness (a measure of α-diversity). As the underlying components of community structure—intraspecific aggregation, interspecific density and the species abundance distribution (SAD)—are potentially impacted in different ways during invasion, trends in species richness provide only limited insight into the mechanisms leading to biodiversity change. In addition, these impacts can be manifested in distinct ways at different spatial scales. Here we take advantage of the new Measurement of Biodiversity (MoB) framework to reanalyse data collected in an invasion front in the Brazilian Cerrado biodiversity hotspot. We show that, by using the MoB multi-scale approach, we are able to link reductions in species richness in invaded sites to restructuring in the SAD. This restructuring takes the form of lower evenness in sites invaded by pines relative to sites without pines. Shifts in aggregation also occur. There is a clear signature of spatial scale in biodiversity change linked to the presence of an invasive species. These results demonstrate how the MoB approach can play an important role in helping invasion ecologists, field biologists and conservation managers move towards a more mechanistic approach to detecting and interpreting changes in ecological systems following invasion.
The Synthesis of Biarylmonophosphonates via Palladium-Catalyzed Phosphonation, Iridium-Catalyzed C-H Borylation, Palladium-Catalyzed Suzuki–Miyaura Cross-Coupling
Authors: Doherty Simon , Knight Julian G. , Tran Tina S. T. , Alharbi Hussam Y. , Perry Daniel O. 
Published: May 2021

Abstract
The iridium-catalyzed C-H borylation of diethyl phenylphosphonate results in nonselective mono and bisborylation to afford a near statistical mixture of 3-, 3,5- and 4-boryl substituted aryl phosphonates whereas 3-substituted aryl phosphonates undergo highly regioselective C-H borylation to afford the corresponding meta-phosphonate substituted arylboronic esters as the sole product; the resulting boronic esters were used as nucleophilic reagents in a subsequent palladium-catalyzed Suzuki–Miyaura cross-coupling to generate a range of biarylmonophosphonates. Gratifyingly, the Suzuki–Miyaura cross-coupling can be conducted without purifying the boronic ester which greatly simplifies the synthetic procedure.

Graphical Abstract
Mendelian randomisation for mediation analysis: current methods and challenges for implementation
Authors: Carter Alice R. , Sanderson Eleanor , Hammerton Gemma , Richmond Rebecca C. , Davey Smith George , Heron Jon , Taylor Amy E. , Davies Neil M. , Howe Laura D. 
Published: May 2021

AbstractMediation analysis seeks to explain the pathway(s) through which an exposure affects an outcome. Traditional, non-instrumental variable methods for mediation analysis experience a number of methodological difficulties, including bias due to confounding between an exposure, mediator and outcome and measurement error. Mendelian randomisation (MR) can be used to improve causal inference for mediation analysis. We describe two approaches that can be used for estimating mediation analysis with MR: multivariable MR (MVMR) and two-step MR. We outline the approaches and provide code to demonstrate how they can be used in mediation analysis. We review issues that can affect analyses, including confounding, measurement error, weak instrument bias, interactions between exposures and mediators and analysis of multiple mediators. Description of the methods is supplemented by simulated and real data examples. Although MR relies on large sample sizes and strong assumptions, such as having strong instruments and no horizontally pleiotropic pathways, our simulations demonstrate that these methods are unaffected by confounders of the exposure or mediator and the outcome and non-differential measurement error of the exposure or mediator. Both MVMR and two-step MR can be implemented in both individual-level MR and summary data MR. MR mediation methods require different assumptions to be made, compared with non-instrumental variable mediation methods. Where these assumptions are more plausible, MR can be used to improve causal inference in mediation analysis.
Approximation and application of the Riesz-Caputo fractional derivative of variable order with fixed memory
Authors: Blaszczyk Tomasz , Bekus Krzysztof , Szajek Krzysztof , Sumelka Wojciech 
Published: May 2021

AbstractIn this paper, the Riesz-Caputo fractional derivative of variable order with fixed memory is considered. The studied non-integer differential operator is approximated by means of modified basic rules of numerical integration. The three proposed methods are based on polynomial interpolation: piecewise constant, piecewise linear, and piecewise quadratic interpolation. The errors generated by the described methods and the experimental rate of convergence are reported. Finally, an application of the Riesz-Caputo fractional derivative of space-dependent order in continuum mechanics is depicted.
Neurostructural and Neurophysiological Correlates of Multiple Sclerosis Physical Fatigue: Systematic Review and Meta-Analysis of Cross-Sectional Studies
Authors: Ellison Paula M. , Goodall Stuart , Kennedy Niamh , Dawes Helen , Clark Allan , Pomeroy Valerie , Duddy Martin , Baker Mark R. , Saxton John M. 
Published: May 2021

Abstract
Fatigue is one of the most debilitating symptoms for people with multiple sclerosis (PwMS). By consolidating a diverse and conflicting evidence-base, this systematic review and meta-analysis aimed to gain new insights into the neurobiology of MS fatigue. MEDLINE, ProQuest, CINAHL, Web of Science databases and grey literature were searched using Medical Subject Headings. Eligible studies compared neuroimaging and neurophysiological data between people experiencing high (MS-HF) versus low (MS-LF) levels of perceived MS fatigue, as defined by validated fatigue questionnaire cut-points. Data were available from 66 studies, with 46 used for meta-analyses. Neuroimaging studies revealed lower volumetric measures in MS-HF versus MS-LF for whole brain (­22.74 ml; 95% CI: -37.72 to -7.76 ml; p = 0.003), grey matter (­18.81 ml; 95% CI: ­29.60 to ­8.03 ml; p < 0.001), putamen (­0.40 ml; 95% CI: ­0.69 to ­0.10 ml; p = 0.008) and acumbens (­0.09 ml; 95% CI: ­0.15 to ­0.03 ml; p = 0.003) and a higher volume of T1-weighted hypointense lesions (1.10 ml; 95% CI: 0.47 to 1.73 ml; p < 0.001). Neurophysiological data showed reduced lower-limb maximum voluntary force production (­19.23 N; 95% CI: ­35.93 to ­2.53 N; p = 0.02) and an attenuation of upper-limb (­5.77%; 95% CI:­8.61 to ­2.93%; p < 0.0001) and lower-limb (­2.16%; 95% CI:­4.24 to ­0.07%; p = 0.04) skeletal muscle voluntary activation, accompanied by more pronounced upper-limb fatigability (­5.61%; 95% CI: -9.57 to -1.65%; p = 0.006) in MS-HF versus MS-LF. Results suggest that MS fatigue is characterised by greater cortico-subcortical grey matter atrophy and neural lesions, accompanied by neurophysiological decrements, which include reduced strength and voluntary activation.
Prospero registration Prospero registration number: CRD42016017934
Evaluation of the similarity between drought indices by correlation analysis and Cohen's Kappa test in a Mediterranean area
Authors: Vergni L. , Todisco F. , Di Lena B. 
Published: May 2021

AbstractIn the literature, numerous papers report comparative analyses of drought indices. In these types of studies, the similarity between drought indices is usually evaluated using the Pearson correlation coefficient, r, calculated between corresponding severity time series. However, it is well known that the correlation does not describe the strength of agreement between two variables. Two drought indices can exhibit a high degree of correlation but can, at the same time, disagree substantially, for example, if one index is consistently higher than the other. From an operational point of view, two indices can be considered in agreement when they indicate the same severity category for a given period (e.g. moderate drought). In this work, we compared six meteorological drought indices based on both correlation analysis and Cohen's Kappa test. This test is typically used in medical or social sciences to obtain a quantitative assessment of the degree of agreement between different methods or analysts. The indices considered are five timescale-dependent indices, i.e. the Percent of Normal Index, the Deciles Index, the Percentile Index, the Rainfall Anomaly Index, and the Standardised Precipitation Index, computed at the 1-, 3-, and 6-month timescales, and the Effective Drought Index, a relatively new index, which has a self-defined timescale. The indices were calculated for 15 stations in the Abruzzo region (central Italy) during 1951–2018. We found that the strength of agreement depends on both the criteria of drought severity classification and the different indices' calculation method. The Cohen's Kappa test indicates a prevailing moderate or fair agreement among the indices considered, despite the generally very high correlation between the corresponding severity times series. The results demonstrate that the Cohen's Kappa test is more effective than the correlation analysis in discriminating the actual strength of agreement/disagreement between drought indices.
Structurally Diverse Sesquiterpenoids with Anti-neuroinflammatory Activity from the Endolichenic Fungus Cryptomarasmius aucubae
Authors: Zhai Yi-Jie , Li Jian-Nan , Gao Yu-Qi , Gao Lin-Lin , Wang Da-Cheng , Han Wen-Bo , Gao Jin-Ming 
Published: May 2021

AbstractTwo new sterpurane sesquiterpenoids named sterpurol D (1) and sterpurol E (2), and one skeletally new sesquiterpene, cryptomaraone (3), bearing a 5,6-fused bicyclic ring system, along with five known ones, sterpurol A (4), sterpurol B (5), paneolilludinic Acid (6), murolane-2α, 9β-diol-3-ene (7) and (–)-10,11-dihydroxyfarnesol (8) were isolated from an endolichenic fungus Cryptomarasmius aucubae. The structures of the new compounds were elucidated by analysis of NMR spectroscopic spectra and HRESIMS data. The absolute configurations of 1 and 2 were established by spectroscopic data analysis and comparison of specific optical rotation, as well as the biosynthetic consideration. Additionally, compounds 1, 2, 4–6, and 8 showed significant nitric oxide (NO) production inhibition in Lipopolysaccharide (LPS)-induced BV-2 microglial cells with the IC50 values ranging from 9.06 to 14.81 μM.
Graphic Abstract
Subthalamic nucleus deep brain stimulation and impulsivity in Parkinson’s disease: a descriptive review
Authors: Lo Buono Viviana , Lucà Trombetta Marietta , Palmeri Rosanna , Bonanno Lilla , Cartella Emanuele , Di Lorenzo Giuseppe , Bramanti Placido , Marino Silvia , Corallo Francesco 
Published: May 2021

AbstractStandard treatment of Parkinson’s disease involves the dopaminergic medications. Deep brain stimulation of the subthalamic nucleus (STN-DBS) is an important neurosurgical intervention often used as alternative treatment to drug therapy; however, it can be associated with increase of impulsive behaviors. This descriptive review focused on studies investigating the correlation between Deep brain stimulation of the subthalamic nucleus and impulsivity in Parkinson’s disease patients, arguing, the action’s mechanism and the specific role of the subthalamic nucleus. We searched on PubMed and Web of Science databases and screening references of included studies and review articles for additional citations. From initial 106 studies, only 15 met the search criteria. Parkinson’s Disease patients with and without Deep Brain Stimulation were compared with healthy controls, through 16 different tasks that assessed some aspects of impulsivity. Both Deep brain stimulation of the subthalamic nucleus and medication were associated with impulsive behavior and influenced decision-making processes. Moreover, findings demonstrated that: Impulse Control Disorders (ICDs) occurred soon after surgery, while, in pharmacological treatment, they appeared mainly after the initiation of treatment or the increase in dosage, especially with dopamine agonists. The subthalamic nucleus plays a part in the fronto-striato-thalamic-cortical loops mediating motor, cognitive, and emotional functions: this could explain the role of the Deep Brain Stimulation in behavior modulation in Parkinson’s Disease patients. Indeed, increase impulsivity has been reported also after deep brain stimulation of the subthalamic nucleus independently by dopaminergic medication status.
Laboratory-based evaluation of a simplified point-of-care test intended to support treatment decisions in non-severe bovine clinical mastitis
Authors: Malcata Francisco B. , Pepler P. Theo , Zadoks Ruth N. , Viora Lorenzo 
Published: May 2021

AbstractTo limit the use of antimicrobials in dairy cattle, farmers are increasingly encouraged to adopt targeted treatment decisions based on knowledge of the pathogens causing clinical mastitis (CM), whereby treatment of non-severe CM is generally recommended for gram-positive mastitis but not for gram-negative or culture-negative mastitis. The objectives of this study were to conduct a laboratory-based evaluation of the performance of a simplified slide test as a tool to differentiate gram-positive CM from other cases of CM, and to compare its performance against a commercially available on-farm test that is commonly used in our area (VétoRapid). Test outcomes after 24–48 h incubation were compared to results from bacteriological culture and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF MS). Milk samples (n = 156) were obtained from cases of severe and non-severe CM on seven farms and collected by farm personnel. After removal of small numbers of contaminated samples and organisms with unknown species identity, the simplified slide test showed high sensitivity and accuracy (>80%), similar to the comparator test. For most outcomes of interest (culture positive, Escherichia coli, or gram-positive growth), the specificity of the slide test was higher than the specificity of the comparator test. When considering non-severe cases of CM only, and interpreting detection of gram-positive organisms as indicative of the need for antimicrobial treatment, the simplified test had higher specificity (77.4% v. 60.4%) and higher positive predictive value (79.7% v. 70.0%) than the comparator test and similar sensitivity (83.9% v. 87.5%). The proportion of sampled CM cases, contaminated samples and gram-positive mastitis cases – which affects the positive and negative predictive value, the economic value of diagnostic testing and its potential to reduce antimicrobial use – differed between farms. The simplicity and accuracy of the slide test could make it an attractive tool for farmers to target antimicrobial treatment of non-severe clinical mastitis.
COVID-19 as a Mass Death Event
Authors: Han Yuna , Millar Katharine M. , Bayly Martin J. 
Published: May 2021

AbstractAs of the first week of February 2021, the COVID-19 pandemic has resulted in over two million people dead across the globe. This essay argues that in order to fully understand the politics arising from the COVID-19 pandemic, we need to focus on the individual and collective experiences of death, loss, and grief. While the emerging scholarly discourse on the pandemic, particularly in political science and international relations, typically considers death only in terms of its effects on formal state-level politics and as a policy objective for mitigation, we argue that focusing on the particularities of the experience of death resulting from COVID-19 can help us fully understand the ways in which the pandemic is reordering our worlds. Examining the ambiguous sociopolitical meaning of death by COVID-19 can provide broader analytical comparisons with other mass death events. Ultimately, the essay argues that centering the impact of the pandemic on the experience of death and loss directly poses the question of how politics should value human lives in the post-pandemic world, helping us better formulate the normative questions necessary for a more ethical future.
EDIFICIO 4, TULA GRANDE: ARCHITECTURE, OCCUPATION, AND ABANDONMENT
Authors: Báez Urincho Fernando 
Published: May 2021

AbstractThis article summarizes recent excavations of Edificio 4 in the Early Postclassic city of Tula, Hidalgo, which, despite prior evidence of its considerable importance, was largely unexcavated. Despite changes in strategy that resulted in discontinuous rather than complete exposure, excavation successfully delineated the entire structure and exposed portions of all or virtually all of its interior rooms, revealing a layout and architectural features notably different from those of the other buildings in Tula's monumental center, and suggest that Edificio 4 had functioned as a palace whose occupants were closely tied to Pyramid B, one of Tula's two largest pyramids. These excavations provide additional perspectives on previously noted similarities between Edificio 4 and the Casa de las Águilas of Aztec Tenochtitlan, revealing striking similarities in layout which, together with equally striking artistic similarities noted previously, make it almost certain that a major portion of the Casa de las Águilas was constructed in the image of the corresponding portion of Tula's Edificio 4.