bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolic effects of 1-week binge drinking and fast food intake during Roskilde Festival in young healthy male adults
Authors: Demant Mia , Suppli Malte P , Foghsgaard Signe , Gether Lise , Grøndahl Magnus F G , Dalsgaard Niels B , Bergmann Sigrid S , Lanng Amalie R , Gasbjerg Lærke S , Thomasen Martin , Bagger Jonatan I , Strandberg Charlotte , Kønig Merete J , Grønbæk Henning , Becker Ulrik , Wewer Albrechtsen Nicolai J , Holst Jens J , Knop Joachim , Gillum Matthew P , Vilsbøll Tina , Knop Filip K 
Published: April 2021

Aims/hypothesis
Metabolic effects of intermittent unhealthy lifestyle in young adults are poorly studied. We investigated the gluco-metabolic and hepatic effects of participation in Roskilde Festival (1 week of binge drinking and junk food consumption) in young, healthy males.

Methods
Fourteen festival participants (FP) were studied before, during and after 1 week’s participation in Roskilde Festival. Fourteen matched controls (CTRL) who did not participate in Roskilde Festival or change their lifestyle in other ways were investigated along a similar timeline.

Results
The FP group consumed more alcohol compared to their standard living conditions (2.0 ± 3.9 vs 16.3 ± 8.3 units/day, P < 0.001). CTRLs did not change their alcohol consumption. AUC for glucose during OGTT did not change in either group. C-peptide responses increased in the FP group (206 ± 24 vs 236 ± 17 min × nmol/L, P = 0.052) and the Matsuda index of insulin sensitivity decreased (6.2 ± 2.4 vs 4.7 ± 1.4, P  = 0.054). AUC for glucagon during oral glucose tolerance test (OGTT) increased in the FP group (1037 ± 90 vs 1562 ± 195 min × pmol/L, P = 0.003) together with fasting fibroblast growth factor 21 (FGF21) (62 ± 30 vs 132 ± 72 pmol/L, P < 0.001), growth differentiation factor 15 (GDF5) (276 ± 78 vs 330 ± 83 pg/mL, P = 0.009) and aspartate aminotransferase (AST) levels (37.6 ± 6.8 vs 42.4 ± 11 U/L, P = 0.043). Four participants (29%) developed ultrasound-detectable steatosis and a mean strain elastography-assessed liver stiffness increased (P = 0.026) in the FP group.

Conclusions/Interpretation
Participation in Roskilde Festival did not affect oral glucose tolerance but was associated with a reduction in insulin sensitivity, increases in glucagon, FGF21, GDF15 and AST and lead to increased liver stiffness and, in 29% of the participants, ultrasound-detectable hepatic steatosis.
Philosophy as a Vocation and Personal Commitment: the Young Heidegger and the Question of Philosophy
Authors: Garrido Periñán Juan José 
Published: April 2021

Determining what philosophy is for the young Heidegger is a complex task. It is also an ambiguous task in that it is considered unresolved and intricate due to its subsidiary link to factical life. This paper will try to show that from the approach of worried concern and from a critique of the theoretical attitude and worldviews, Heidegger conceives that philosophizing is committing oneself to the possibility of carrying out a personal transformation lived as a commitment of a personal nature. From this situation, which will be critically scrutinized in the development of the present paper, I will determine philosophy to be the setting in motion of the self-enlightenment of the life of each existent.
The Problem of Experience in E. Voegelin’s Philosophy
Authors: Caturianas Dovydas 
Published: April 2021

The paper deals with the problem of E. Voegelin’s notion of experience: the positive meaning of this concept is not specified in any of the author’s works. Based on W. James’s ‘‘Essay on Radical Empiricism” and Voegelin’s late works, it is shown that Voegelin’s theory of consciousness is rooted in James‘s concept of “pure experience”, which essentially sought to close the epistemological chasm between subject and object, phenomena and noumena. According to this notion, mental and physical, subjective and objective realities are merely derivative aspects of a certain primordial pure experience, which is more elementary and fundamental than the two former aspects of reality. Finally, the article exposes other implications of this connection with James’s philosophy for E. Voegelin’s theory of consciousness.
Existence Results for a Class of p(x)-Kirchhoff Problems
Authors: Allaoui Mostafa 
Published: April 2021

This paper is concerned with the existence of solutions to a class of p(x)-Kirchhoff-type equations with Robin boundary data as follows:Where and satisfies Carathéodory condition. By means of variational methods and the theory of the variable exponent Sobolev spaces, we establish conditions for the existence of weak solutions.
Fostering Campus-Wide Dialogue and Student-Centered Learning through Film Festivals and Media Projects: Engaging Chinese Environmental Issues beyond the Asian Studies Classroom
Authors: Blumenfield Tami 
Published: April 2021

Based on a Luce Initiative on Asian Studies and the Environment Pilot-Year Project at Furman University This article discusses how film festivals and other media projects can be used to engage students in hands-on learning while also immersing campus communities in topics of broad concern. A Chinese Environmental Film Festival held at Furman University in 2015 is used as a case study to examine how students can develop festival programming, learning about films as well as developing skills related to multimedia communication, teamwork, and event planning. Beyond the students directly involved with planning the festival, faculty, staff and students from other classes also benefit from the activities related to the festival, which can be used to extend learning in their own courses. The interdisciplinary potential of film festivals and their adaptability to a wide variety of topics make them particularly well suited to liberal arts college settings, though they can be used effectively on larger campuses as well.
Methylation of the SNRPN gene in infertile men without mutations in common candidate genes for reduced fertility
Authors: Mikhaylenko D. S. , Simonova О. A. , El Akel I. , Sobol I. Yu. , Edoyan Т. A. , Efremov Е. A. , Kuznetsova E. B. , Nemtsova М. V. 
Published: April 2021

Introduction. Male infertility is a common problem in andrology and occurs in 45 % of infertile couples. Some cases of male infertility caused by genetic reasons: point mutations at some monogenic diseases, AZF deletions or a CFTR mutation compounds; reduced fertility is also associated with polymorphic variants of the genes AR and GSTT1/GSTM1. At the same time, increasing amount of data are being published about the role of epigenetic mechanisms (aberrant methylation and imprinting alterations) in defective spermatogenesis.Materials and methods. We have studied 49 sperm samples obtained from unrelated infertile men using polymerase chain reaction, fragment analysis, and sequencing.Results. Five patients were excluded from the initial cohort: one with a repeat length of 29 (CAG) in the first exon of the AR, three with null genotypes in the GSTT1 and GSTM1, and one with the delF508/5T heterozygous compound in the CFTR. Thereafter, methylation of the imprinted gene SNRPN was determined using methyl-specific polymerase chain reaction and bisulfite sequencing. Aberrant SNRPN methylation was detected in 11.4 % of male infertility samples. In total, molecular genetic and epigenetic alterations were determined in 20 % of patients.Conclusions. Obtained data demonstrate a significant proportion of (epi)genetic disorders in a heterogeneous cohort of men with reduced fertility.
Augmentation of the urethral plate in the glans penis area and the distal urethra – effective method of fistula correction in children with hypospadias
Authors: Rudin Yu. E. , Maruhnenko D. V. , Rudin A. Yu. , Aliev D. К. , Lagutin G. V. , Vardak А. В. 
Published: April 2021

Background. Important causes of complications of hypospadias repair are the deficit of tissues for plastic surgery, grooveless and small size of glans, obliteration of the urethral platewith varying degrees of scarring. The coronal urethral fistula is the most common complication of urethroplasty. Surgeons continue to search for reliable methods of correction of complications.Materials and methods. Between 2011 and 2019, 85 children aged 2 and 17 years presented with coronal fistula of urethra after hypospadias repair. (TIP) Snodgrass – 78 (91.7 %) and Mathiue – 7 (8.2 %) procedures have been performed them earlier. In our clinic previously operated 28 (32 %) boys, primary surgery of the remaining 57 (67 %) was performed in other medical institutions.Results. All patients (85), conditionally, were divided into two groups. The first group included 39 children (45.8 %), with stitching a fistula, the second group consisted of 46 patients (54.1 %), with augmentation of the urethral plate of the glans and distal urethra with the implantation of a rectangular preputial or oral mucosa free graft. Recurrent urethral fistula after stitching was observed in 10 boys (25.6 %) of the first group, and only in 2 cases (4.3 %) in children with the augmentation of the urethral plate (p <0.05). The decrease of urine flow according to the data of uroflowmetry was observed in 15 patients (52 %) the first group, the children of the second group did not have a decrease in the flow of urine.Discussion. The shape, size of the glans and the condition of the urethral plate affect to the result of urethroplasty. The connection of the wings of the glans in accordance with normal anatomy, avoid obstruction in the distal part of urethra. A wide urethra in the glans and meatal area improves urine flow. Conclusion. The augmentation of the urethral plate of the penile glans and the distal urethra with the implantation of a wide rectangular free flap in to the meatus, in our opinion, an advantage over the implantation of diamond-shaped grafts using the GTIP or TIP graft technique.
Possibilities of conservative treatment for andrological conditions in men with history of COVID-19
Authors: Popova A. Yu. , Gamidov S. I. , Shatylko Т. V. , Gasanov N. G. , Ovchinnikov R. I. , Gamidov R. S. 
Published: April 2021

Novel coronavirus infection 2019 (COVID-19), which is caused by SARS-CoV-2 (severe acute respiratory syndrome related coronavirus-2), leads to a growing concern for public healthcare worldwide. Question about whether SARS-CoV-2 is able to penetrate into testicular tissue and/or seminal fluid remains unanswered. Fertility specialists also encounter many issues regarding prevention and treatment of infertility in patients with a history of COVID-19. There is an increasing number of publications which demonstrate anti-inflammatory, antiviral and antioxidant properties of socalled adaptogenic plants. This was the reason to analyze published articles on the effects of antioxidants and adaptogens on reproductive function in males with a history of COVID-19.
Memórias‌ ‌de‌ ‌Carolina:‌ ‌revisão‌ ‌histórica‌ ‌e‌ ‌contestação‌ ‌política‌ ‌em‌ <i>‌‌Diário‌ ‌de‌ ‌Bitita‌</i>‌ (1982/86)
Authors: Espallargas Teresa 
Published: April 2021

A escritora mineira Carolina Maria de Jesus é reconhecida por seu trabalho autobiográfico, sobretudo, na obra Quarto‌ ‌de‌ ‌Despejo‌‌: Diário de uma favelada, que a colocou no circuito literário paulistano e brasileiro na década de 60. O gênero percorreu a carreira da autora até seu último livro, publicado postumamente em 1982 na França, e 1986 no Brasil, intitulado Diário de Bitita. Bitita era o apelido de infância de Jesus e é a ela que pertence este diário. O foco do presente artigo é, pois, na análise desta obra escrita durante os anos finais de vida da autora, com intuito de revelar que além do evidente uso das escritas de si, esta narrativa transpõe o universo da experiência pessoal e, ao estilo Guattari e Deleuze de “literatura menor” mistura presente e passado, história, meta-memória e literatura a fim de questionar a conservação do sistema político ‌e‌ ‌da‌ ‌condição‌ ‌da‌ ‌população‌ ‌negra‌ ‌no Brasil.
Analisis Penghasilan, Pekerjaan, dan Usaha Masyarakat di Masa Pandemi Melalui Penerapan Data Sains
Authors: Nafi'iyah Nur , Maghfiroh Syafaatul 
Published: April 2021

Activities in some sectors experience a decrease in revenue due to the Covid-19 outbreak, for example, the business of traders who experience a decline turnover. From some respondents who work in the field of trade, entrepreneurship, self-employment experience the impact of the Covid-19 pandemic. This can be seen from the results of questionnaire distributed through google form https://bit.ly/2DiRYzL. Despite the pandemic, work and learning activities still have to run online, for example, conducting online Student Community Service (KKN), with socialization activities to fill out questionnaires related to the impact of the Covid-19 pandemic. In addition, the author also held online KKN activities by promoting tourist attractions in Sekaran village through https://www.youtube.com/watch?v=Ed3bdRIxlpY. The purposes of distributing questionnaire are to know the impact of the pandemic and in order to obtain solutions. This questionnaire was distributed to KKN places, namely Sekaran, Babat, Kebonsari, Turi, Kentong, Tunggul, Priyoso villages in Lamongan Regency, and Bayureno, Bojonegoro, and Banyulegi Mojokerto. The questionnaires that have been completed were then analyzed using basic statistics such as average value, maximum value, and minimum value. The results of the distribution of questionnaires obtained 990 respondents, with an analysis of 77% of respondents experienced changes in income during the pandemic. Jobs affected by Covid-19 are traders, entrepreneurs, self-employed, farmers and online hired motorcycle drivers. Their incomes decreased by 50% to 68%. There were 43 layoffs out of 990 respondents.
PERJANJIAN SEWA MENYEWA MOBIL YANG MENIMBULKAN WANPRESTASI DI KABUPATEN BANTUL
Authors: Fadilah Fredi Ahmad , Heriyani Endang 
Published: April 2021

Perjanjian sewa menyewa pada perusahaan persewaan mobil sering terjadi wanprestasi. Tujuan dalam penelitian, yaitu mengetahui wanprestasi dan bentuk penyelesaian apabila terjadi wanprestasi pada perusahaan persewaan mobil yaitu CV. GH Tour and Travel, CV. Cahya Tour, dan CV. Mae Trans. Metode Penelitian: Jenis penelitian ini adalah penelitian hukum normatif-empiris. Teknik Pengumpulan Data menggunakan Metode Interview atau wawancara, observasi dan dokumentasi. Teknik Analisis Data menggunakan teknik kualitatif, penelitian ini menggunakan metode silogisme dan interpretasi. Hasil penelitian menunjukkan Perjanjian Sewa Menyewa Mobil Yang Menimbulkan Wanprestasi di Kabupaten Bantul yaitu Penyewa merusak objek sewa. Penyelesaiannya dilakukan dengan cara meminta uang ganti sewa atas biaya servis kendaraan selama berada dalam masa perbaikan. Penyewa terlambat mengembalikan objek kendaraan. Penyelesaiannya dilakukan dengan cara memberikan biaya denda kepada pihak penyewa, perhitungan untuk keterlambatan dihitung setiap jamnya dan besarnya denda adalah 10% dari harga sewa mobil yang disewa. Penyewa menyewakan ulang obyek kendaraan. Penyelesaiannya dilakukan dengan meminta biaya kerugian dan meminta uang hasil dari penyewa yang mengulang sewakan obyek sewa kepada pihak ketiga
Promoting Positive Mental Health in International Postgraduate Law Students at a Time of Global Uncertainty: A Case Study from qLegal at Queen Mary, University of London
Authors: Wapples Emily 
Published: April 2021

Law student mental health and wellbeing was already a growing concern in the UK prior to COVID-19, but when the pandemic occurred, widespread uncertainty placed an unprecedented level of mental health burden on students. Law students were faced with dashed hopes, uncertain futures and the fear of negative academic consequences. This burden was exacerbated in respect of postgraduate international students in London, who were often also forced to decide whether to return home to their families, or to continue their studies abroad, albeit online.
This paper uses a case study approach to discuss how one provider of postgraduate clinical legal education (CLE), approached the promotion of positive student mental health both before, and in response to, the pandemic. qLegal at Queen Mary, University of London provides CLE to postgraduates studying for a one year law masters, and in 2019-2020, qLegal delivered CLE to 134 students from 27 countries. The impact that the pandemic had on the mental health of international postgraduate law students was therefore witnessed first-hand.
This paper discusses the challenges faced, and concerns raised by international postgraduate law students at qLegal as a result of the pandemic. It examines the steps taken by qLegal to maximise student engagement and promote positive student mental health when rapidly switching to a model of online delivery. The paper concludes by outlining the steps qLegal will take to monitor and address the impact that online delivery in this period of global uncertainty has on the mental health of the next cohort of postgraduate CLE students.
Analysis of Quality of Antibiotic Usage on Patient with Internal and Surgical Service
Authors: Ma'rifah Nurul , Hasmono Didik , Hadi Usman , Kuntaman Kuntaman 
Published: April 2021

It is well-known that hospitals are health facility with the widely use of antibiotics. It is about 13-37% from the total hospitalized patients in developed countries use antibiotic, even in developing countries can reach 30-80%. There is identified correlation between antibiotic use and the development of bacterial resistance. Even though the resistance cannot be eliminated, but its development can be suppressed by the increasing of prudent use of antibiotics. The aim of this study was to determine the quality of antibiotic use on internal medicine and surgical patients in Aisiyah Hospital Bojonegoro. The study was a prospective cross sectional observational analytical study of among patients of internal and surgical who received antibiotic therapy in the period of August - September 2017. The total 50 samples were collected in this study which consists of 33 internal medicine and 17 surgical patients. From 50 samples, there were 16 types of antibiotics with the total use of 81 of antibiotic use. As the result, in internal medicine patients there were 22 (40%) of appropriate use of antibiotics, 4 (7.27%) of inappropriate use and 29 (52.73%) use of antibiotics without indication. In surgical patients, there were 12 (46.15%) of appropriate use of antibiotics, 2 (7.69%) of inappropriate use and 12 (46.15%) use of antibiotics without indication. This study showed that more than 50% of antibiotic use were inappropriate, and mainly antibiotic with no indication, among patients hospitalized in Aisyiyah Hospital Bojonegoro.
Completion Total Thyroidectomy in Occult Thyroid Cancer Patients after Partial Thyroidectomy
Authors: Syahrudi Syahrudi , Wijayahadi R Yoga 
Published: April 2021

Thyroid cancer is one of the commonest cancer while the incidence of occult thyroid cancer is only 0,05%. Completion total thyroidectomy as one of the treatment choice for thyroid cancer which initially diagnosed preoperatively as benign thyroid mass, remains controversial. The aim of this study is to understand the effectiveness of completion total thyroidectomy after partial thyroidectomy, by analyzing from: proportion of malignant contralateral thyroid tissue, post operative complications, and recurrence of cancer. This retrospective study collected medical record datan between 2011 and 2016. Total sample were 16 patients (15 females, 1 male). There was no significant difference on contralateral thyroid tissue malignancy proportion between completion total thyroidectomy and without total thyroidectomy (p=0,375). It was found 3 surgical complications (50%) from 6 patients with completion total thyroidectomy and 3 complications (30%) from 10 patients without completion total thyroidectomy. The complications were temporary injury of recurrent laryngeal nerve (p=0,511), seroma (p=0,375), and hypoparathyroidism (p=0,375). No recurrence event after 4 years follow up amount both groups. In conclusion, there is no advantage in completion total thyroidectomy analized from proportion of malignant contralateral thyroid tissue, post operative complication and recurrence in 4 years-follow up.
Neuromuscular Taping Increases Muscle Strength, Flexibility, and Shortens The 100 Meter Sprinter Travel Time
Authors: Endaryanto Agung Hadi , Asnar Elyana , Indrawati Roostantia 
Published: April 2021

Lari sprint atau lari jarak pendek adalah salah satu nomor dalam atletik yang paling bergengsi, pelarinya disebut Sprinter. NMT adalah tehnik aplikasi yang menggunakan elastic adhesif tape yang memberikan kemampuan peningkatan fungsional otot, dan stimulasi sistem saraf. Tujuan penelitian ini, untuk mengetahui pengaruh neuromuscular taping terhadap kekuatan otot, fleksibilitas otot dan waktu tempuh sprinter 100 meter. Penelitian ini menggunakan metode pre test-post test with control grup design dengan total sampel berjumlah 13 orang dengan rentang usia atlet 15-19 tahun, pada tanggal 4-5 Agustus 2016 di GOR Gresik. Metode 1 kelompok dengan 2 perlakuan yaitu perlakuan I sebelum pemberian NMT dilakukan pengukuran kekuatan otot, fleksibilitas otot, dan waktu tempuh berlari 100 meter dan sesudah pemberian NMT dilakukan pengukuran kembali, perlakuan 2 sebagai kelompok kontrol dilakukan tanpa pemberian NMT dilakukan pengukuran kekuatan otot, fleksibilitas otot, dan waktu tempuh berlari 100 meter. Hasil penelitian menunjukkan pada perlakuan 1 kekuatan otot gastrocnemius dengan peningkatan rerata 11,38±7,83kg, nilai p=0,000, fleksibilitas nilai p=0,003 (dorsofleksi), p=0,013 (plantarfleksi) dengan peningkatan rerata 3,46±4,27 derajat, dan pemendekan waktu tempuh dengan nilai p=0-001, pada perlakuan 2 kekuatan otot gastrocnemius dengan penurunan rerata 2,12±2,43kg, nilai p=0,009, fleksibilitas nilai p=1,000 (dorsofleksi), p=0,165 (plantarfleksi) dengan peningkatan rerata 0,77±1,88 derajat, dan waktu tempuh terjadi perpanjangan waktu dengan nilai p=0-001 . Pemberian NMT pada sprinter memberikan hasil yang lebih baik dalam peningkatan kekuatan otot, fleksibilitas otot dan memperpendek waktu tempuh.
The Big Move: Five Mass Transport To Ankara City Hospital
Authors: BEKGÖZ Burak , ŞAN İshak , ERGİN Mehmet , SARI Eyüp , USUL Eren 
Published: April 2021

Aim
It is a rare need for IHT that an existing hospital is scheduled to be closed. In this study, the process of Mass Transport due to the relocation of five different hospitals to a single target hospital is discussed.
Methods
Meetings were held with hospital administrators to plan the Mass Transport and an emergency transport action plan was decided. During the planning phase of the Mass Transport, each hospital was examined separately and in-hospital and inter-hospital transfer routes were created. During the Mass Transport, spare ambulances were activated to avoid disrupting the daily workflow of emergency medical services (EMS). In addition, EMS administrations of nearby provinces were asked to send their spare ambulances to Ankara. While 1 driver and 2 paramedics were assigned to a stable patient transport team, 1 driver, 1 paramedic and 1 doctor were assigned to a critical patient transport team.
Results
The patients who were transported from the clinics comprised 24.95% (n = 130) of all transported patients. Of all patients transported, 56.81% (n = 296) were males. The mean age of all transported patients was 46.33 ± 26.04 years (min-max; 0 - 93) (46.21 ± 26.45 years for females, 46.43 ± 25.56 years for males).

Conclusion
Pre-transport planning and measures are crucial for the safe transport of patients, especially in large-scale IHTs. In addition, an effective communication system ensures a trouble-free transport.