bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tuning the Growth Pattern of Triangular Silver Nanoplates from Lateral to Vertical by Secondary Metal Addition
Authors: Kluitmann Jonas , Csáki Andrea , Fritzsche Wolfgang , Köhler Johann Michael 
Published: December 2024

AbstractWe are presenting an easy synthetic access to the aqueous synthesis of truncated trigonal silver nanobipyramids with tunable width and height in a facile two step synthesis. We modified a synthesis that employs seed particles with twinning faults on which silver is deposited laterally along the twinning fault, leading to flat particles. The ratio of lateral and vertical growth is adjusted by the co‐titration of further noble metal salts at nanomolar concentrations alongside the silver precursor. Thus, besides the edge lengths, the thickness and related aspect ratio of metal bipyramids can be tuned. By tracking the growth of the particles via their localized surface plasmon resonance position during the reaction using optical transmission spectroscopy, we present insights into the modification of the growth mechanism for truncated silver nanobipyramids.
Special expression of alanine‐aminotransferase1 (OsAlaAT1) improves nitrogen utilization in wheat
Authors: Jiao Bo , Wang Jiao , Dong Fushuang , Yang Fan , Liu Yongwei , Sun Lei , Chai Jianfang , Zhou Shuo 
Published: December 2024

AbstractNitrogen is an essential macronutrient for crop development and growth. However, nitrogen‐based fertilizer application not only increases the cost of crop production systems, but also causes serious environmental pollution and low nitrogen use efficiency (NUE) in cereal crops. To enhance the NUE of wheat (Triticum aestivum L.), the transgenic approach was used to create a new variety. In this study, the rice (Oryza sativa L.) alanine‐aminotransferase1 (OsAlaAT1), an important nitrogen assimilation enzyme affecting the NUE of plants, was transformed into wheat under the control of TaAnt1 promoter. Special expression of OsAlaAT1 enhanced the height and 1000‐kernel weight of wheat. It also affected the expression level of starch synthesis‐related genes in seeds at 10 and 15 days after pollination. Independent lines expressing OsAlaAT1 exhibited higher grain production than wild‐type plants under high‐nitrogen and, especially, low‐nitrogen supplementation. Our results suggest that OsAlaAT1 improves the NUE of wheat.
A system dynamic analysis of corporate carbon disclosure in China
Authors: Li Mengna , Pu Chenxi , Yuan Sai 
Published: December 2024

AbstractCarbon disclosure has become an important bridge for businesses and the public to interact positively in addressing climate change. Existing research has already answered which factors affect corporate carbon disclosure, but has not yet described the interaction between multiple influencing factors and the entire process of corporate carbon disclosure. This study constructed the system dynamics model of corporate carbon disclosure based on demand and supply of information, trying to explore the process of corporate carbon disclosure and the influencing mechanism of influencing factors. The results demonstrate that information asymmetry is a prerequisite for corporate to disclose carbon information. The motivation for the company to disclose carbon information mainly stems from the information needs of external stakeholders. Among the expected impacts of the government, public, and investors, carbon disclosure strategies are most affected by government expectations. Environmental supervision promotes the speed at which companies adjust the carbon disclosure level rather than the final level of carbon disclosure. The government's penalties will not change the final level and adjustment speed of carbon information disclosure. Government rewards can effectively improve the final level of corporate carbon disclosure in the future. The conclusion provides reference and guidance for regulatory authorities to further regulate corporate carbon disclosure and create a stable and transparent capital market environment.
Extramedullary Hematopoiesis in Serous Cavity Fluids: A Closer Look at This Rare Phenomenon With Diagnostic Pitfalls and Prognostic Significance
Authors: Sakshi F. N. U. , Mallikarjuna Vinay Sakaleshpura , Stewart John M. , Gan Qiong 
Published: December 2024

ABSTRACTBackgroundExtramedullary hematopoiesis (EMH) is usually seen in the reticuloendothelial system such as the spleen and liver; however, there have been rare case reports when EMH is seen in serous fluids (SFs). The aim of this study included analyzing the cytomorphological features of EMH in SFs in correlation with various clinicopathologic parameters and recognizing potential diagnostic pitfalls as well as their prognostic significance.MethodsClinicopathologic parameters and radiologic and pathologic information from the patients with a cytologic diagnosis of EMH were evaluated with cytology slides.ResultsThe cytomorphologic features of EMH and diagnostic pitfalls were evaluated. Seven patients with cytologically determined EMH in SF samples, including five pleural fluids, one ascitic fluid, and one cerebrospinal fluid, were identified over the past 20 years at a comprehensive cancer center. Their mean age was 67.5 years. Most patients (n = 5) had a history of advanced myelofibrosis.ConclusionsThis study uncovered methods to differentiate EMH from peripheral blood (PB) contamination in samples in the SF. PB contamination is an important differential for EMH, and cytomorphology remains a salient parameter for the diagnosis. The comparison of the number of red blood cells and white blood cells in the PB and SF helped to distinguish EMH from PB contamination when megakaryocytes were absent. The study showed that most patients died within a year of their EMH diagnosis in SF, suggesting a strong prognostic association of this finding with poor survival outcomes.
Rare Earth Acylpyrazolonates‐Synthesis, Structure, Luminescent Properties and Applications
Authors: Belousov Yuriy A. , Drozdov Andrei A. , Shikin Daniil D. , Tombesi Alessia , Pettinari Riccardo , Marchetti Fabio , Pettinari Claudio 
Published: December 2024

AbstractAcylpyrazolonate derivatives of rare earth elements (REE), being a non‐mainstream class of β‐diketonates, have continued to attract chemists and materials scientists for more than half a century. The electronic structure features of these ligands make them effective sensitizers of the luminescence of various lanthanides, emitting in the visible and IR regions. Exhibiting all the typical structural types of β‐diketonates, acylpyrazolonates can form heterometallic complexes with d‐elements due to the presence of additional donor atoms. The review covers more than half a century of the history of these compounds and provides a perspective on the development of this class of compounds and their transformation into materials of the 21st century.
Chiral 2D Halide Perovskites for Piezoelectric Energy Harvesting and Ultrasound Detection
Authors: Li Hongtao , Zhao Xue‐Zhou , Yang Hai‐Run , Guo Tian‐Meng , Li Wei , Feng Rui 
Published: December 2024

AbstractHybrid organic‐inorganic perovskite (HOIPs) has emerged as a great promising class of piezoelectric materials due to their solution processability, ease of structural adjustment, and high piezoelectricity. However, to date, their energy application and ultrasound detection has been relatively unexplored. Here, a pair of chiral two‐dimensional (2D) HOIPs, R‐/S‐[3MeOPEA]2PbBr4 (3MeOPEA=1‐(3‐Methoxyphenyl) ethylamine), were synthesized, and the structure, photoluminescence and piezoelectric properties are reported. Our results demonstrate these materials exhibit consistent broad PL peaks under 360 nm excitation and density functional theory (DFT) calculations reveal their direct bandgap characteristic. Moreover, the incorporation of chirality into the structure of R‐ and S‐[3MeOPEA]2PbBr4 endows them with significant piezoelectric properties. 5 wt% R‐[3MeOPEA]2PbBr4/PDMS (polydimethylsiloxane) composite film can generate a maximum open‐circuit piezoelectric voltages (Voc) of 1.98 V and short circuit currents (Isc) of 0.50 μA upon a loading force of 2 N at 10 Hz. Additionally, the device can sensitively detect ultrasound waves underwater at varying distances of 3, 6, and 9 mm, with corresponding peak‐to‐peak voltage (Vp‐p) responses of 52.3 mV, 41.1 mV, and 31.7 mV, respectively. Our research broadens the potential applications of multifunctional chiral 2D perovskite materials in the fields of piezoelectric energy harvesting and underwater ultra‐sound detection.
Retrofitting Homes: Cost of Mitigation Strategies for Improved Wildfire Resistance
Authors: Barrett Kimiko , Quarles Stephen L. 
Published: December 2024

ABSTRACTAs wildfire risks increase, it is essential to retrofit the existing housing stock in wildfire‐prone areas to reduce community wildfire risk. Yet there are significant questions regarding the costs and most effective strategies to retrofit homes for improved wildfire resistance. This article identifies the costs for retrofitting homes to meet the requirements specified by Chapter 7A (Materials and Construction Methods for Exterior Wildfire Exposure) in the California Building Code. Guidance from recent research related to ignition‐resistant construction was also utilized. Construction costs were calculated as a per‐unit value and were explicit to the exterior components of the home. Detailed estimates are offered for upgrading a home's exterior walls, roof, deck, windows and doors, under‐eave areas, gutters, and near‐home landscaping. Analysis demonstrates that some of the most effective strategies to reduce structure vulnerability to wildfire can be done affordably. This analysis suggested that for a typical 2000‐square‐foot home in California, retrofitting costs can be as low as $2000 for minimal retrofits to $100,000 for the highest level of protection.
Identification of the Heptapeptide PR7 and Octapeptide SF8 With Potent Antioxidative and Angiotensin Converting Enzyme Inhibitory Activity From the Fermented Dairy By‐Product “Buttermilk”
Authors: Magouz Osama , Ibrahim Mahmoud A. A. , Mehanna Nabil , Gensberger‐Reigl Sabrina , Dalabasmaz Sevim , Pischetsrieder Monika 
Published: December 2024

ABSTRACTThe present study aimed to identify antioxidative and angiotensin converting enzyme (ACE) inhibitory peptides in fermented buttermilk after simulated gastric digestion. Following isoelectric focusing fractionation, peptides of the most active fractions were identified by ultrahigh performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS). Subsequently, 23 peptides were synthesized and tested for antioxidative and ACE inhibitory activity. The peptide PR7 (PWDQVKR, αs2‐casein 108–114) exerted comparable antioxidative activity to ascorbic acid, whereas the peptide SF8 (SGPLRPFF, butyrophilin 427–434) efficiently inhibited ACE with an IC50 value of 1.57 µM. The binding modes of the five most active ACE inhibitors were predicted using AlphaFold2 multimer software. Molecular mechanics (MM) minimization and molecular dynamics (MD) simulations of all complexes, followed by MM‐generalized born surface area (GBSA) binding energy calculations, were predicted. Notably, these peptides manifested good binding affinities to ACE. The estimated MM‐GBSA/MD binding energies correlated with the detected IC50 values [correlation coefficient (R2) = 0.79]. Post‐MD analyses over 100 ns elucidated the steadiness of the five peptides.
Serpentine Supravenous Hyperpigmentation, a Phenomenon Following the Administration of Chemotherapeutic Agents: A Systematic Review
Authors: Radkhah Hanieh , Maleki Saba , Arabzadeh Bahri Razman 
Published: December 2024

ABSTRACTBackgroundSerpentine supravenous hyperpigmentation (SSH) is known as a phenomenon occurring during the infusion of chemotherapy agents in the underlying veins. Chemotherapy agents have potential to cause infusion reactions when used systematically. Linear hyperpigmentation and reticular hyperpigmentation are the differential diagnosis for this phenomenon. The aim of the present study was to systematically review the serpentine supravenous dermatitis induced by chemotherapeutic agents.MethodsA comprehensive search was conducted in Scopus, PubMed, Embase, and Web of Science bibliometric databases on February 7, 2023. The search keywords were categorized into two groups: SSH and chemotherapy. Any combination between keywords was used for the systematic search. We included any type of article that evaluated the SSH in cancer patients after the infusion of chemotherapeutic agents, including observational studies with at least one eligible patient based on our criteria, case series, and case reports. Studies that reported SSH in non‐cancer patients or caused by any medications other than chemotherapeutic agents were excluded.ResultsTwenty‐five studies were included based on our inclusion criteria consisting of 26 patients. A total of 13 different cancers were reported in the included studies. Lung cancer was the most reported cancer. Also, the mostly reported region of this dermatitis was forearm which was reported in 13 studies. Docetaxel has been used in a total of 11 articles in this study and has independently induced serpentine supravenous dermatitis in seven studies, which is the mostly reported chemotherapeutic agent resulting into serpentine supravenous dermatitis. Most of these skin lesions were self‐limiting and with a normal histopathological finding.ConclusionSSH is a dermatologic reaction, which mostly occur when there is peripheral venous access for the injection of chemotherapeutic agents. The skin lesion will improve spontaneously and have a benign course with no abnormal histopathological pathological finding.
Gaps in the protection of the amphibians of Myanmar—threat status, endemism, protected area coverage and One Plan Approach conservation
Authors: Borgwerth Marie , Scholten Carolin , Lin Aung , Thura Myint Kyaw , Grismer Larry Lee , Ziegler Thomas , Rödder Dennis 
Published: December 2024

AbstractCurrently, 41% of amphibian species are threatened with extinction, leading to the ongoing amphibian crisis. In Myanmar, the amphibian diversity is still poorly understood, and, as a result, many conservation gaps remain. To increase the knowledge about Myanmar's amphibians and thus provide an opportunity to fill the gaps in conservation in the country, we assess the species in greater detail. To do so, we compile a species list of the amphibians of Myanmar through various sources and evaluate their threat status using the IUCN Red list. We perform richness analyses to compare the distribution areas of the amphibian species of Myanmar to the distribution of the protected areas (PAs) in the country. We evaluate the representation of Myanmar's amphibians in zoos worldwide through the Zoological Information Management System (ZIMS) to check the implementation of the One Plan Approach to Conservation. Our results suggest that there are 152 amphibian species extant in Myanmar, of which 25 are endemic to the country. 4.6% (n = 7) of all species are classified as threatened, but counting those with insufficient available data as possibly threatened increases the number to 44.1% (n = 67). Of them, 40 species are not covered by any of Myanmar's PAs. That includes 28.6% of the threatened, 35.7% of the potentially threatened, and 48% of the endemic species. According to the ZIMS database, none of Myanmar's threatened, potentially threatened, or endemic amphibian species are kept in any zoo or aquarium worldwide, suggesting that the One Plan Approach is not sufficiently implemented as a conservation measure for Myanmar's amphibians. With this study, we show conspicuous gaps in the protection of Myanmar's amphibians and provide a list of the 36 most threatened species, recommending a possible prioritization for upcoming conservation actions.
The Centers for Disease Control and Prevention opioid guideline revisions and pharmacy practice: An opinion of the American College of Clinical Pharmacy Pain and Palliative Care Practice and Research Network
Authors: Emshoff Jessica B. , Theken Katherine N. , Juba Katherine M. , Trombetta Dominick P. , Denham Hannah , Carr Megan , Love Nancy , Page Mackenzie , Uebbing Emily , Lehr Victoria Tutag 
Published: December 2024

AbstractThe Centers for Disease Control and Prevention revised their Clinical Practice Guideline for Prescribing Opioids for Pain in 2022. This opinion paper was prepared by members of the American College of Clinical Pharmacy (ACCP) Pain and Palliative Care Practice and Research Network (PRN) and provides an overview of updates to the 2022 guidelines, highlighting major changes from the 2016 guidelines and calling attention to the opportunities and challenges for pharmacists in providing patient‐centered care with opioids for pain management. While this paper represents the opinion of the ACCP Pain and Palliative Care PRN, it does not necessarily represent an official ACCP commentary, guideline, or statement of policy or position.
Attention Versus Handshakes: Pathways of Influence in China's Foreign Aid and Loans
Authors: Lu Lucie , Williams Miles 
Published: December 2024

ABSTRACTNumerous studies show that China uses its ODA‐like overseas development financing to promote soft power and improve its international image. In this study, we seek to understand how. We examine the role of Chinese state‐sponsored media and diplomacy as complements to Chinese foreign aid. We propose that the coverage of aid recipients in Xinhua articles targeted at foreign audiences, as well as the number of diplomatic visits from Beijing hosted by a recipient government, increase in proportion to the amount of aid these countries receive from China. In contrast, we propose either a null or reverse relationship in the case of OOF‐like flows from China, which tend to be more associated with loans and business‐oriented interests. To test these hypotheses, we use AidData's Chinese development finance dataset and its recently released diplomacy dataset, along with meta‐data from millions of Xinhua news articles between 2002 and 2017. The analysis provides partial support for our argument, but the results deviate from our expectations in interesting ways. First, while aid (ODA) recipients receive more coverage in Xinhua, they are not disproportionately more likely to host missions from Beijing. Conversely, while loan (OOF) recipients are not more likely to receive coverage in Xinhua, they are more likely to host diplomatic visits. These results suggest that China likes to publicize its role as a donor for image building, but seeks closer ties with its debtors to further bilateral relationships.
HCC Model Induced by P53 and Pten Knockout in HBV‐Transgenic Mice Mirrors Human HCC at the Transcriptome Level
Authors: Chen Zhao , Yang Jing , Song Yang , Chen Xiangmei , Duan Yuan , Wang Jingzhou , Liu Yongzhen , Guan Guiwen 
Published: December 2024

ABSTRACTWith a multitude of HCC mouse models available, choosing the one that most closely resembles human HCC can be challenging. This study addresses this gap by conducting a comprehensive transcriptomic similarity analysis of widely used HCC mouse models. In this study, RNA‐seq was performed on a model induced by double knockout of P53 and Pten via CRISPR/Cas9 in HBV‐transgenic mice. Additionally, RNA‐seq data from 2345 various other models induced by different methods were collected from GEO databases. The gene expression profiles, immune microenvironments, and metabolic pathways of these models were compared with those of human HCC. The analysis revealed distinct transcriptomic features among the different models. The HBV + P53&Pten KO model demonstrated the highest overall similarity to human HCC across various parameters. It shared a high degree of overlap in differentially expression genes (DEGs) between tumor and non‐tumor tissues with human HCC, exhibited a transcriptome profile and immune cell infiltration pattern closely resembling human HCC, and showed metabolic alterations similar to those in human HCC. Conversely the DEN + CCl4‐induced model showed the lowest similarity to human HCC in transcriptome profiles and DEGs and exhibited a distinct immune microenvironment with high NK cell infiltration, with minimal metabolic differences between tumor and non‐tumor tissues. This study highlights the importance of selecting appropriate HCC mouse models for research. The HBV + p53&Pten KO model emerged as the most promising due to its remarkable similarity to human HCC across various aspects.
A model of near‐sea ice phytoplankton blooms
Authors: Lester C. W. , Wagner T. J. W. , McNamara Dylan E. 
Published: December 2024

ABSTRACTArctic phytoplankton spring blooms have increased in magnitude and extent over the past two decades, particularly in waters near the sea ice edge. We develop an idealized model of phytoplankton dynamics that takes into account the role of sea ice meltwater flux and its impact on surface mixed layer depth. Satellite observations feature a characteristic peak in phytoplankton concentration at around 100 km from the ice edge. Model dynamics capture this peak and overall structure of the phytoplankton distribution. In the model, the characteristic spatial scale emerges from a balance of exponential growth near the ice edge, horizontal advection, and increased decay with distance from the ice as the mixed layer deepens. Observations and data further agree in that meltwater impacts phytoplankton concentrations up to 1000 km from the ice edge. Results suggest that reduced meltwater input under future sea ice retreat may suppress spring phytoplankton blooms in the region.
Multiphoton Microscopy Assessment of Healing From Tendon Laceration and Microthermal Coagula in a Rat Model
Authors: Montague Jenna E. , Hutchens Gabrielle V. , Howard Caitlin C. , Rice Photini F. S. , Besselsen David G. , Slayton Michael , Utzinger Urs , Barton Jennifer K. , Sawyer Travis W. 
Published: December 2024

ABSTRACTObjectivesTo study the healing response of rat Achilles tendon when lacerated or treated with intense therapeutic ultrasound (ITU) via utilization of multiphoton microscopy (MPM) imaging and histology.Materials and MethodsThe right Achilles tendon of each Sprague Dawley rat within a cohort was partially lacerated. 1 to 2 days post‐surgery, each rat received ITU treatment of the Achilles tendon on either the right or left leg. Rats were euthanized in groups at 1, 3, 7, 14, or 28 days posttreatment and their tendons were explanted, formalin fixed, paraffin embedded, sectioned, and placed on slides for imaging. Slides from each time point were imaged using a laboratory built MPM with a 780 nm Ti:Sapphire laser. The resulting second harmonic generation (SHG) and two‐photon excited fluorescence (2PEF) signals were captured, assessed, and compared to brightfield microscopy images of the same section subsequently stained with hematoxylin and eosin.ResultsAt early timepoints, 2PEF images show the presence of red blood cells, infiltration of inflammatory cells and formation of a fibrin clot at laceration sites, and attraction of fibroblasts to ITU coagula. SHG images indicate an absence of organized collagen in both types of lesions. At later timepoints, new organized collagen can be seen at the laceration sites, and the concentration of inflammatory cells has noticeably decreased. Automated detection of red blood cells and infiltrative cells, as well as analysis of SHG signal intensity and homogeneity was performed at laceration locations. Results show that all quantities except SHG signal intensity approach normal values by day 28. Thus, combined analysis of 2PEF and SHG images elucidates tendon healing processes that align with and complement histological findings.ConclusionThese results indicate that multiphoton imaging can effectively visualize the healing response to mechanical (laceration) and thermal (ITU) injury, including the organization of new collagen which is more difficult to visualize with histology.