bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Emergence of a Rhizomatic Mode of Consciousness through Body Movement: Ethnography of Taijiquan Martial Artists
Authors: Paul Tomáš 
Published: July 2021

AbstractTaijiquan is a Chinese martial art currently passed on in its various forms worldwide. The following text draws a map of bodies, places, and entities that compose the act of becoming a Taijiquan practitioner in the Czech Republic. The purpose of this study is to create a space for a discussion between the research of martial arts and the anthropology of consciousness by illustrating the transformations of consciousness that originate in years or decades of rigorous martial art practice. This focus contrasts traditional anthropology of consciousness subjects as there is no significant immediate shift of consciousness from “ordinary” to “extraordinary” states—a result of the different rhythm and tempo of practicing Taijiquan. The theoretical framework that allows this discussion is inspired by Deleuze and Guattari's cosmology, which proves useful for understanding those longitudinal changes in consciousness. Their conceptions of the arborescent and rhizomatic provide a tool to illustrate consciousness as an ever‐changing map, never stabilized in a normal conserved state as it outlines how the dissolution of borders of consciousness (deterritorialization) should always be observed complementarily with their tightening (reterritorialization).
An investigation into the effects of ocular nebulization combined with meibomian gland massage on ocular surface status and corneal higher‐order aberrations for the treatment of meibomian gland dysfunction
Authors: Lin Fangyu , Mao Xinjie , Ma Lirong , Liu Huiying 
Published: July 2021

AbstractPurposeTo evaluate ocular surface status and corneal higher‐order aberrations after a new ocular nebulization therapy combined with meibomian gland massage for the treatment of meibomian gland dysfunction (MGD).Patients and methodsThis prospective randomized study involved 38 patients diagnosed with MGD. Subjects were classified into two groups: the nebulization and meibomian gland massage group (or NB group, 14 patients, 28 eyes) and the eye drop group (or ED group, 24 patients, 48 eyes). Azithromycin solution and esculin and digitalis glycoside eye drops were tested in the therapy. Best‐corrected visual acuity (BCVA) testing; noncontact tonometry; fundoscopy; the Ocular Surface Disease Index (OSDI) questionnaire; tear film assessment encompassing tear meniscus height (TMH) and non‐invasive keratograph breakup time (NIKBUT); corneal fluorescein staining; the Schirmer I test (SIT); and anterior, posterior and total corneal aberrations were evaluated at 1 and 3 months after treatment.ResultsAt 3 months, the NB group showed significantly better improvement than the ED group in terms of TMH (0.23 ± 0.04 versus 0.19 ± 0.05, p = 0.002) and first breakup time (f‐BUT; 7.42 ± 2.49 versus 5.53 ± 2.12, p = 0.001). The average breakup time (Av‐BUT) of the NB group was significantly longer than that of the ED group at 1 month (9.52 ± 2.70 versus 8.02 ± 2.33, p = 0.013) and 3 months (5.53 ± 2.12 versus 8.35 ± 2.38, p = 0.018). Both groups achieved improvement in corneal fluorescein staining (CFS) and SIT results at 1 and 3 months (p < 0.05). At the 3‐month follow‐up, anterior corneal trefoil aberrations decreased significantly in the NB group (p = 0.008), and improvements in anterior corneal coma aberrations and posterior corneal higher‐order aberrations (HOAs) were observed in the ED group (p < 0.05) over the 4 mm pupil zone. Over a 6 mm zone at 3 months, anterior, posterior and total trefoil aberrations as well as total HOAs were significantly decreased in the NB group (p < 0.05), while posterior HOAs and trefoil aberrations were found to be decreased in the ED group (p < 0.05). For individual Zernike terms, anterior and total corneal Z(3, −3) showed decreases over the 4 and 6 mm zones, while no improvement was detected in the NB group at 3 months.ConclusionIn terms of comfort and visual quality, nebulization therapy combined with meibomian gland massage to deliver azithromycin solution and esculin and digitalis glycoside eye drops appears to be more effective in treating clinical symptoms and signs of MGD than simply applying esculin and digitalis glycoside eye drops.
PRESERFLO™ MicroShunt versus trabeculectomy: first results on efficacy and safety
Authors: Pillunat Karin R. , Herber Robert , Haase Maike A. , Jamke Melanie , Jasper Carolin S. , Pillunat Lutz E. 
Published: July 2021

AbstractPurposeTo report efficacy and safety outcomes of the PRESERFLO™ MicroShunt compared with trabeculectomy, the current gold‐standard treatment for advanced glaucoma, in the early and intermediate postoperative period.MethodsInstitutional prospective interventional cohort study of primary open‐angle glaucoma (POAG) patients scheduled for the PRESERFLO™ MicroShunt. The comparison group were POAG patients who had had received trabeculectomy and were matched for age, known duration of disease, number and classes of intraocular pressure (IOP)‐lowering medications to ensure a similar conjunctival condition. The study is part of the Dresden Glaucoma and Treatment Study (DGTS), was not randomized, but used a uniform study design, with the same inclusion and exclusion criteria as well as standardized definitions of success and failure. Main outcome measures: mean diurnal IOP (mdIOP, mean of 6 measurements), diurnal peak IOP, diurnal IOP fluctuations, glaucoma medical therapy, success rates, visual acuity, visual fields, surgical complications and interventions, and severe adverse events.ResultsFifty‐two eyes of 52 patients, 26 in each group, were analysed. At 6 months, median [Q25, Q75] mdIOP was 10.8 [9.5–12.2] mmHg in the microshunt and 10.3 [7.6–11.8] mmHg in the trabeculectomy group. Reduction in mdIOP (p = 0.458), peak diurnal IOP (p = 0.539), and median diurnal fluctuation (p = 0.693) was not statistically significantly different between groups. The rate of interventions was statistically significantly higher in the trabeculectomy compared with the microshunt group (p = 0.004). None of the patients experienced severe adverse events.ConclusionBoth procedures are equally effective and safe in lowering mdIOP in patients with POAG. Because the microshunt is less invasive with less follow‐up and interventions needed postoperatively, it might be recommended earlier in the treatment of glaucoma.
Multi‐inflammatory syndrome and Kawasaki disease in children during the COVID‐19 pandemic: A nationwide register‐based study and time series analysis
Authors: Koskela Ulla , Helve Otto , Sarvikivi Emmi , Helminen Merja , Nieminen Tea , Peltola Ville , Renko Marjo , Saxén Harri , Pasma Hanna , Pokka Tytti , Honkila Minna , Tapiainen Terhi 
Published: July 2021

AbstractAimWe investigated whether the ongoing COVID‐19 pandemic was associated with the occurrence of Kawasaki disease or with multi‐inflammatory syndrome in children (MIS‐C).MethodsThis national Finnish register‐based study was based on laboratory‐confirmed severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infections, MIS‐C and Kawasaki disease cases. We performed a time series analysis on the occurrence of Kawasaki disease in 2016–2020.ResultsIn 2020, there were 5170 laboratory‐confirmed COVID‐19 cases in children under 18 years of age and five fulfilled the MIS‐C case definition. The occurrence of MIS‐C was 0.97 per 1000 (95% confidence interval: 0.31‐2.26) laboratory‐confirmed SARS‐CoV‐2 infections in children. Our time series analysis showed that Kawasaki disease cases decreased during the COVID‐19 pandemic. The seasonally adjusted incidence rate ratio was 0.49 (95% confidence interval: 0.32‐0.74) when it was compared to pre‐pandemic levels. This coincided with a reduced occurrence of respiratory infections, due to social distancing in the population.ConclusionThis nationwide register‐based study found that MIS‐C was a rare complication of the SARS‐CoV‐2 infection. The occurrence of Kawasaki disease and respiratory infections decreased during the pandemic. This suggests that transmissible microbes may play an important role in Kawasaki disease and social distancing may have a protective effect.
Editorial: volatile organic compound analysis to improve faecal immunochemical testing in the detection of colorectal cancer
Authors: Hanna George B. , Cross Amanda J. 
Published: July 2021

LINKED CONTENTThis article is linked to Chandrapalan et al papers. To view these articles, visit https://doi.org/10.1111/apt.16405 and https://doi.org/10.1111/apt.16511
Editorial: non‐erosive reflux disease is often not GERD—time to change the definition or abandon the term?
Authors: Katz Philip 
Published: July 2021

LINKED CONTENTThis article is linked to Kim et al and Kim & Park papers. To view these articles, visit https://doi.org/10.1111/apt.16477 and https://doi.org/10.1111/apt.16510
Letter: predictive model for gastric cancer after eradication of Helicobacter pylori—a survival analysis using a deep learning algorithm
Authors: Arai Junya , Aoki Tomonori , Hayakawa Yoku , Niikura Ryota , Suzuki Nobumi , Yamada Atsuo , Hirata Yoshihiro , Koike Kazuhiko 
Published: July 2021

LINKED CONTENTThis article is linked to Leung et al and Lui & Leung papers. To view these articles, visit https://doi.org/10.1111/apt.16272 and https://doi.org/10.1111/apt.16499
Editorial: topiramate for cyclic vomiting syndrome—for refractory patients only?
Authors: Rangan Vikram , Lembo Anthony J. 
Published: July 2021

LINKED CONTENTThis article is linked to Mooers et al papers. To view these articles, visit https://doi.org/10.1111/apt.16457 and https://doi.org/10.1111/apt.16516
Letter: is there no conclusive evidence for the effect of tranexamic acid on mortality in gastrointestinal bleeding?
Authors: Lin Yu‐Ci , Chen Chia‐Yun , Chang Chun‐Chao , Kang Yi‐No 
Published: July 2021

LINKED CONTENTThis article is linked to Chang et al paper. To view this article, visit https://doi.org/10.1111/apt.16261
Letter: tofacitinib in treatment‐refractory ulcerative colitis—a single centre real‐world experience in Australia. Authors' reply
Authors: Biemans Vince B. C. , Straatmijer Tessa , Hoentjen Frank , Pierik Marieke J. 
Published: July 2021

LINKED CONTENTThis article is linked to Biemans et al and Lo et al papers. To view these articles, visit https://doi.org/10.1111/apt.15689 and https://doi.org/10.1111/apt.16468
Editorial: inconclusive diagnosis of GERD—are new parameters in impedance‐pH‐metry ready for clinical use?
Authors: Sergeev Ilia , Sifrim Daniel 
Published: July 2021

LINKED CONTENTThis article is linked to Ribolsi et al papers. To view these articles, visit https://doi.org/10.1111/apt.16481 and https://doi.org/10.1111/apt.16529
Letter: response of eosinophilic oesophagitis to proton pump inhibitor therapy—the importance of biopsies at index endoscopy
Authors: Chen Lynna , Glance Simon , Garg Mayur 
Published: July 2021

LINKED CONTENTThis article is linked to Frazzoni et al paper. To view this article, visit https://doi.org/10.1111/apt.16371
Editorial: an elastography‐based two‐step approach to detect NAFLD with compensated advanced chronic liver disease—authors' reply
Authors: Zhou Yu‐Jie , Zheng Ming‐Hua 
Published: July 2021

LINKED CONTENTThis article is linked to Zhou et al and Wong papers. To view these articles, visit https://doi.org/10.1111/apt.16487 and https://doi.org/10.1111/apt.16507
“Work Is Mandaa”: Breadwinning, Sexual Fitness, and Anti‐Productivism among Cycle Rickshaw Men in North India
Authors: Beckhorn Patrick 
Published: July 2021

AbstractMen who migrate to Delhi, India, from West Bengal to fulfill the male breadwinner expectation by operating cycle rickshaws claim that business is slow, which keeps their families’ expectations for remittances low and helps camouflage their slacking. Slacking is a crucial activity in light of the men’s belief that operating a cycle rickshaw dries out their bodies such that it reduces their sexual fitness. Their laziness supports the masculine goal of remaining sexually fit, and when they privilege this goal over the demand for productivity inherent in the breadwinner role, the standard analytic of productive versus reproductive labor becomes untenable. It is instead argued that the men’s behavior reveals a limited case of anti‐productivism. Studies of anti‐productivism are usually confined to Western workers, and those that take gender into account usually focus on workers’ gendered positions in society’s division of labor. This article shows how clashes between gender ideals at the somatic level can provoke an anti‐productivist response. It also shows that tension between culturally particular ideas about the embodied consequences of labor performance and workers’ gendered body ideals can have profound effects on the workers’ orientation to their labor.1
Uberized Care: Employment Status, Surveillance, and Technological Erasure in the Home Health Care Sector
Authors: Glaser Alana Lee 
Published: July 2021

AbstractThe emergence of hailing and platform labor applications across industries has generated productive theorizing on new forms of worker control, exploitation, and data commodification. Yet, despite their significant use of labor brokerage platforms, care workers are overlooked in political and scholarly analyses of the current platform‐based economy. In this article, I describe two facets of the United States home health‐care industry to identify how the problems of platform labor—namely, loss of employee status coupled with decentralized oversight and routinization—germinated in the highly exploitative realm of home health care for decades prior to uberized and gig‐economy capitalism. In so doing, I consider how technological oversight of remote care workers codifies care in accordance with managerial priorities and reimbursement protocols and I argue that for‐profit home‐care jobs in the United States presaged processes of precarity, decentralization, surveillance, codification, and data generation that now appear nearly ubiquitous across industries.
Good Mothers and Good Workers: Discipline and Care in Chile's Grape‐Packing Plants
Authors: Radovic‐Fanta Jelena 
Published: July 2021

AbstractThis article explores the affective dimensions of precarious labor in Chile's grape‐export industry in the centrally located Aconcagua Valley. Although the country's billion‐dollar fruit industry is marked as an example of successful development, female seasonal workers (calledtemporeras) navigate hazardous working conditions and noncompliance of labor laws. Contrary to common assumptions of workers' alienation from labor, their personal identities are deeply entangled in their workplace. This article examines how management invokes temporeras' identities as mothers and care providers as a disciplinary mechanism. At the same time, workers articulate motherhood as a form of endurance. Although efforts by the Chilean government attempt to regulate the fruit‐export sector, there is a dismal lack of enforcement of recent labor laws. As a result, temporeras bear the burden of safeguarding their physical well‐being. I conclude by suggesting that social relations and the moral textures of everyday interactions provide the possibilities through which workers endure precarious labor.
Updated results of the placebo‐controlled, phase III JAKARTA trial of fedratinib in patients with intermediate‐2 or high‐risk myelofibrosis
Authors: Pardanani Animesh , Tefferi Ayalew , Masszi Tamás , Mishchenko Elena , Drummond Mark , Jourdan Eric , Vannucchi Alessandro , Jurgutis Mindaugas , Ribrag Vincent , Rambaldi Alessandro , Koh Liang Piu , Rose Shelonitda , Zhang Jun , Harrison Claire 
Published: July 2021

SummaryFedratinib, an oral Janus kinase‐2 (JAK2) inhibitor, reduces splenomegaly and improves symptom burden in patients with myelofibrosis. Regulatory approval of fedratinib 400‐mg daily was based on results of an updated analysis of the pivotal phase III, placebo‐controlled JAKARTA trial in patients with JAK‐inhibitor‐naïve myelofibrosis. At week 24, spleen volume response rate was 47% and symptom response rate was 40% with fedratinib 400 mg, versus 1% and 9% respectively, with placebo. Common adverse events were diarrhoea, nausea, anaemia, and vomiting. No Wernicke encephalopathy occurred in patients receiving fedratinib 400 mg/day. These updated data support use of first‐line fedratinib in patients with myelofibrosis.
Statin use and survival in 16 098 patients with non‐Hodgkin lymphoma or chronic lymphocytic leukaemia treated in the rituximab era
Authors: Brånvall Elsa , Ekberg Sara , Eloranta Sandra , Wästerlid Tove , Birmann Brenda M. , Smedby Karin E. 
Published: July 2021

SummaryStatin use has been associated with reduced mortality from several cancers but also suggested, in vitro, to diminish the effectiveness of lymphoma treatments including rituximab. The present study aimed to assess the association of statin use with mortality in patients with non‐Hodgkin lymphoma (NHL) and chronic lymphocytic leukaemia (CLL). We identified all incident NHLs and CLLs in Sweden from 2007 to 2013 with subtype information in the Swedish Lymphoma and Cancer Registers. Using Cox regression, we estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for the association of pre‐ or post‐diagnosis statin use (yes/no, intensity) with lymphoma‐specific, cardiovascular, or all‐cause mortality; and for follicular lymphoma (FL) by initial treatment strategy (active/watch‐and‐wait). Among 16 098 incident NHL/CLL patients, 20% used statins at diagnosis. Pre‐ and post‐diagnosis statin use, and statin intensity were not consistently associated with any mortality outcome in patients with NHL, overall or for any subtype. For actively treated patients with FL, statin use did not appear to increase lymphoma‐specific mortality (vs. non‐users, HR [95% CI]after diagnosis 0·87 [0·45–1·67]). For CLL, statin use was associated with all‐cause and cardiovascular but not consistently with lymphoma‐specific mortality. In conclusion, statin use was not associated with improved lymphoma survival but appears safe to use during lymphoma treatment.
Towards PET imaging of the dynamic phenotypes of microglia
Authors: Beaino Wissam , Janssen Bieneke , Vugts Danielle J , de Vries Helga E , Windhorst Albert D 
Published: July 2021

Abstract
There is increasing evidence showing the heterogeneity of microglia activation in neuroinflammatory and neurodegenerative diseases. It has been hypothesized that pro-inflammatory microglia are detrimental and contribute to disease progression, while anti-inflammatory microglia play a role in damage repair and remission. The development of therapeutics targeting the deleterious glial activity and modulating it into a regenerative phenotype relies heavily upon a clearer understanding of the microglia dynamics during disease progression and the ability to monitor therapeutic outcome in vivo. To that end, molecular imaging techniques are required to assess microglia dynamics and study their role in disease progression as well as to evaluate the outcome of therapeutic interventions. Positron emission tomography (PET) is such a molecular imaging technique, and provides unique capabilities for non-invasive quantification of neuroinflammation and has the potential to discriminate between microglia phenotypes and define their role in the disease process. However, several obstacles limit the possibility for selective in vivo imaging of microglia phenotypes mainly related to the poor characterization of specific targets that distinguish the two ends of the microglia activation spectrum and lack of suitable tracers. PET tracers targeting translocator protein 18 kDa (TSPO) have been extensively explored, but despite the success in evaluating neuroinflammation they failed to discriminate between microglia activation statuses. In this review, we highlight the current knowledge on the microglia phenotypes in the major neuroinflammatory and neurodegenerative diseases. We also discuss the current and emerging PET imaging targets, the tracers and their potential in discriminating between the pro- and anti-inflammatory microglia activation states.
Reduced infiltration of regulatory T cells in tumours from mice fed daily with gamma-tocotrienol supplementation
Authors: Subramaniam Shonia , Anandha Rao Jeya Seela , Ramdas Premdass , Ng Mei Han , Kannan Kutty Methil , Selvaduray Kanga Rani , Radhakrishnan Ammu Kutty 
Published: July 2021

Abstract
Gamma-tocotrienol (γT3) is an analogue of vitamin E with beneficial effects on the immune system, including immune-modulatory properties. This study reports the immune-modulatory effects of daily supplementation of γT3 on host T helper (Th) and T regulatory cell (Treg) populations in a syngeneic mouse model of breast cancer. Female BALB/c mice were fed with either γT3 or vehicle (soy oil) for 2 weeks via oral gavage before they were inoculated with syngeneic 4T1 mouse mammary cancer cells (4T1 cells). Supplementation continued until the mice were euthanized. Mice (n = 6) were euthanized at specified time-points for various analysis (blood leucocyte, cytokine production and immunohistochemistry). Tumour volume was measured once every 7 days. Gene expression studies were carried out on tumour-specific T lymphocytes isolated from splenic cultures. Supplementation with γT3 increased CD4+ (p &lt; 0.05), CD8+ (p &lt; 0.05) T-cells and natural killer cells (p &lt; 0.05) but suppressed Treg cells (p &lt; 0.05) in peripheral blood when compared to animals fed with the vehicle. Higher interferon (IFN)-γ and lower transforming growth factor (TGF)-ꞵ levels were noted in the γT3 fed mice. Immunohistochemistry findings revealed higher infiltration of CD4+ cells, increased expression of interleukin-12 receptor-beta-2 (IL-12ꞵ2R), interleukin (IL)-24 and reduced expression of cells that express the forkhead box P3 (FoxP3) in tumours from the γT3-fed animals. Gene expression studies showed the down-regulation of seven prominent genes in splenic CD4+ T cells isolated from γT3-fed mice. Supplementation with γT3 from palm oil-induced T cell-dependent cell-mediated immune responses and suppressed T cells in the tumour microenvironment in a syngeneic mouse model of breast cancer.
Selective laser trabeculoplasty: A review
Authors: Landers John 
Published: July 2021

AbstractGlaucoma is the second most prevalent cause of blindness worldwide, and the only effective management is the lowering of intraocular pressure (IOP). Selective laser trabeculoplasty (SLT) has become an essential part of glaucoma management since its commercial release in 2001. It has been an improvement from the previous argon laser trabeculoplasty (ALT), by using 1% of the laser energy, reducing the amount of anterior segment inflammation and minimising the degree of mechanical injury to the trabecular meshwork. There is now a large volume of work that demonstrates SLT is equally effective as ALT and topical medication in lowering IOP. It is simple to perform, with a well described side‐effect profile, and is long‐lasting and repeatable. This review will summarise the current literature on SLT for each of these topics.