bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Type 2 Diabetes Subtype Responsive to ACCORD Intensive Glycemia Treatment
Authors: Mariam Arshiya , Miller-Atkins Galen , Pantalone Kevin M. , Zimmerman Robert S. , Barnard John , Kattan Michael W. , Shah Hetal , McLeod Howard L. , Doria Alessandro , Wagner Michael J. , Buse John B. , Motsinger-Reif Alison A. , Rotroff Daniel M. 
Published: April 2021

OBJECTIVECurrent type 2 diabetes (T2D) management contraindicates intensive glycemia treatment in patients with high cardiovascular disease (CVD) risk and is partially motivated by evidence of harms in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Heterogeneity in response to intensive glycemia treatment has been observed, suggesting potential benefit for some individuals.RESEARCH DESIGN AND METHODSACCORD was a randomized controlled trial that investigated whether intensively treating glycemia in individuals with T2D would reduce CVD outcomes. Using a novel approach to cluster HbA1c trajectories, we identified groups in the intensive glycemia arm with modified CVD risk. Genome-wide analysis and polygenic score (PS) were developed to predict group membership. Mendelian randomization was performed to infer causality.RESULTSWe identified four clinical groupings in the intensive glycemia arm, and clinical group 4 (C4) displayed fewer CVD (hazard ratio [HR] 0.34; P = 2.01 × 10−3) and microvascular outcomes (HR 0.86; P = 0.015) than those receiving standard treatment. A single-nucleotide polymorphism, rs220721, in MAS1 reached suggestive significance in C4 (P = 4.34 × 10−7). PS predicted C4 with high accuracy (area under the receiver operating characteristic curve 0.98), and this predicted C4 displayed reduced CVD risk with intensive versus standard glycemia treatment (HR 0.53; P = 4.02 × 10−6), but not reduced risk of microvascular outcomes (P &lt; 0.05). Mendelian randomization indicated causality between PS, on-trial HbA1c, and reduction in CVD outcomes (P &lt; 0.05).CONCLUSIONSWe found evidence of a T2D clinical group in ACCORD that benefited from intensive glycemia treatment, and membership in this group could be predicted using genetic variants. This study generates new hypotheses with implications for precision medicine in T2D and represents an important development in this landmark clinical trial warranting further investigation.
El hombre: animal que venera, animal que desconfía. Historia natural de la moral y de las pasiones en la obra de Nietzsche
Authors: Piazzesi Chiara 
Published: April 2021

A través del proyecto de una «historia natural de la moral», podemos entender algunos puntos del planteamiento de Nietzsche, donde la «naturaleza» humana, es decir, la fisiología y la psicología humana, está conectada con la moralidad, con las normas e instituciones. Explorando estas conexiones a través de los ejemplos de las pasiones (especialmente la del amor), este trabajo discute el enfoque antropológico que le sirve de base a la mencionada «historia natural de la moral». Se pretende así clarificar la importancia de tomar conciencia de los supuestos antropológicos (a menudo implícitos) que se esconden detrás de todo proyecto filosófico que busque trasformar la autocomprensión humana.
La forma literaria y la crisis de la edad madura en «Así habló Zaratustra»
Authors: Higgins Kathelen 
Published: April 2021

El relativo desinterés en Así habló Zaratustra entre los estudiosos de Nietzsche refleja el fracaso de reconocer lo que la forma literaria contribuye a su mensaje filosófico. La elección de la forma ficcional en sentido amplio posibilita a Nietzsche explorar sus ideas sobre las posibilidades de vivir una vida llena de sentido en el mundo contemporáneo occidental, donde el nihilismo, a raíz de la muerte de Dios, está comenzando a renacer. Así habló Zaratustra ilumina por tanto aspectos de la propia comprensión de Nietzsche de su proyecto filosófico, una concepción que contrasta con la orientación contemporánea dominante. Bosquejo alguno de estos aspectos fijándome en cuatro características inusuales de Zaratustra: 1) su planteamiento parecido a los dibujos animados de sus personajes y acción; 2) su presentación disfrazada de primera persona y el posicionamiento resultante del lector; 3) sus rasgos «musicales»; y 4) su singularidad como un Bildungsroman [no-vela de formación] de la madurez.
Study on the Classification of Forestry Infrastructure from the Perspective of Supply Based on the Classical Quartering Method
Authors: Zhang Liying , Zhang Jingyi , Zhang Lixiu , Wu Chengliang , Zhang Yang 
Published: April 2021

Abstract
Complete forestry infrastructure is the material basis for the realization of forestry production, ecology, and social functions. In order to clarify the scope of duties of forest infrastructure suppliers, this paper analyzes the characteristics of forestry infrastructure from the perspective of main suppliers, and summarizes forestry infrastructure as a material engineering facility that provides public services for forestry production, forestry economics, and social and ecological functions. The classical quartering method of goods was used to classify forestry infrastructure, which is divided into four categories: private goods, crowded public goods, club goods, and pure public goods.
Has the belt and road initiative boosted the resident consumption in cities along the domestic route? – evidence from credit card consumption
Authors: Zhen Li , Yao Zhang 
Published: April 2021

Abstract
The Belt and Road (B&R) is a major initiative and vision for China and the world to jointly create prosperity. Based on the data of resident credit card consumption in 291 cities in China from 2011 to 2016, this article establishes a consumption relationship model for cities along the B&R to investigate the impact of the initiative on resident consumption. Through the DID model, there are the following findings. First, the B&R Initiative has a significant positive impact on the resident consumption in cities along the route. Second, the B&R Initiative has a significant effect on the promotion of various industries, and the crowding-out effect of government investment is relatively small. The research conclusions are of reference significance for policy formulation on the specific practice path and detailed measures of the B&R Initiative.
Effects of internal/external EGR and combustion phase on gasoline compression ignition at low-load condition
Authors: Gong Jingyu , Yang Binbin , Liu Leilei , Liang Yue , Zhang Zhifa , Zhang Fan 
Published: April 2021

Abstract
A single-cylinder test engine model was built by GT-Power software, and the effects of internal exhaust gas recirculation (i-EGR), external EGR (e-EGR), i-EGR/e-EGR coupling and the crank angle degree at which 50% of total heat loss has taken place (CA50) on combustion and emission characteristics of gasoline compression ignition at low-load condition were analysed. The results show that the ignition delay period with e-EGR was extended slightly with the increased EGR ratio, while that with i-EGR strategy first shortened and then extended, and that the optimised indicated thermal efficiency could be achieved using a small amount of i-EGR. With the same EGR ratio, nitrogen oxide (NO
X
) emission is more likely to be suppressed by i-EGR, while soot emission was more deteriorated, and the superior trade-off relationship between carbon monoxide (CO)/hydrocarbon (HC) emissions and NO
X
emission was attained by the combination of lower i-EGR ratios and CA50 closed to top dead centre. When using i-EGR/e-EGR coupling with total EGR ratio being fixed, the indicated thermal efficiency was decreased by increasing i-EGR ratio, while the lower NO
X
, CO and HC emissions could be realised, but only with the consequence that soot emission increased.
Gődel filters in residuated lattices
Authors: Piciu Dana , Dan Christina Theresia , Dina Anca 
Published: April 2021

Abstract
In this paper, in the spirit of [4], we study a new type of filters in residuated lattices : Gődel filters. So, we characterize the filters for which the quotient algebra that is constructed via these filters is a Gődel algebra and we establish the connections between these filters and other types of filters. Using Gődel filters we characterize the residuated lattices which are Gődel algebras. Also, we prove that a residuated lattice is a Gődel algebra (divisible residuated lattice, MTL algebra, BL algebra) if and only if every filter is a Gődel filter (divisible filter, MTL filter, BL filter). Finally, we present some results about injective Gődel algebras showing that complete Boolean algebras are injective objects in the category of Gődel algebras.
Improvement of Physical Properties of Viscose using Nano GEO2 as Doping Material
Authors: Daneshian Hamed , Nayebzadeh Shahnaz , Davodiroknabadi Abolfazl 
Published: April 2021

Abstract
The properties of viscose\TiO2 and viscose\TiO2\germanium dioxide (GeO2) are investigated and compared. The elemental mapping analysis using a field emission scanning electron microscope (FESEM) shows the excellent distribution of nanomaterials, while the energy dispersive X-ray (EDX) confirms its existence. The 500 s cycle of rubbing test indicates that the abrasion resistance of treated samples improves significantly. In addition, the doping of nano GeO2 enhances the strength of the treated samples. Furthermore, the thermal behavior of the treated samples, characterized by differential scanning calorimeter (DSC), results in a higher crystallization temperature and doping GeO2 increases the thermal properties of viscose in comparison with nano TiO2. The study of ultraviolet blocking indicates that doping GeO2 can improve the transmission of ultraviolet even from TiO2.
Relationship between salicylic acid and resistance to mite in strawberry
Authors: Vilela de Resende Juliano T. , Matos Rafael , Zeffa Douglas M. , Constantino Leonel Vinicius , Alves Silas M. , Ventura Maurício U. , Resende Nathalia C. V. , Youssef Khamis 
Published: April 2021

Abstract
The two-spotted spider mite (TSSM) Tetranychus urticae is a polyphagous pest which infests several wild and cultivated species of plants worldwide. To date, this mite is the most deleterious pest attacking the strawberry plant under a protected environment. Exogenously applied salicylic acid (SA) has been found to induce resistance to biotic and abiotic stresses. Morpho-anatomical changes in strawberry leaflets and TSSM preference tests were investigated in response to SA treatment. Plants grown in a greenhouse were foliar sprayed with different concentrations of SA (0 mg · L−1, 25 mg · L−1, 50 mg · L−1, 75 mg · L−1 and 100 mg · L−1). After the third application, certain parameters including the number of glandular and non-glandular trichomes, thickness of leaflet, abaxial cell wall, adaxial cell wall, palisade and lacunous parenchyma and mesophyll were measured using scanning electronic microscopy (SEM). Two-choice and non-choice assays were employed to verify the TSSM preference. Exogenous treatment with SA promoted morpho-anatomical changes in the following parameters, namely: thickness of the leaflets, mesophyll, lacunous and palisade parenchyma, cell wall (abaxial and adaxial) and the number of glandular and non-glandular trichomes in strawberry leaflets. In general, TSSM preferred less leaflets treated with SA compared with the control in a two-choice assay. A lesser number of TSSM eggs and live females were also recorded in leaflets treated with SA compared with the control plants in no-choice assays. The values of the number of eggs and live females correlated negatively with those obtained for the morpho-anatomical traits induced by exogenous SA.
In the Shadow of the Lost Crown. ‘Oppressed Innocence’ in the Operas Dedicated to Maria Clementina Sobieska in Rome (1720–1730)
Authors: Markuszewska Aneta 
Published: April 2021

Abstract
As a result of the Glorious Revolution of 1688, James II Stuart lost the throne of England, Scotland, and Ireland. He spent the last years of his life in France, in residence offered to his family and court by Louis XIV. Following his death in 1701, the title and claim to the throne of the three kingdoms was inherited by his son James III Stuart, who in 1719 married Maria Clementina Sobieska (1702–1735). James and his wife extended their patronage over one of Rome's major opera houses, the Teatro d’Alibert, at which 16 operas were dedicated to that couple in 1720–1730. Of those 8 that honoured Maria Clementina, 4 (half of them) deal with the topic of ‘oppressed innocence’, previously passed over by scholars studying the couple's patronage. These are: Eumene, (lib. A. Zeno, mus. N. Porpora, 1721), Adelaide, (lib. A. Salvi, mus. N. Porpora, 1723), Siroe, re di Persia, (lib. Metastasio, mus. N. Porpora, 1727), and Artaserse, (lib. Metastasio, mus. L. Vinci, 1730). This paper analyses the said operatic theme and attempts to explain why it is the dominant subject in operas dedicated to Sobieska. It also studies the political and propagandist potential which that theme could have for the Stuart cause.
Bronisław Mirski - Polish Music Director of the Silent Film Era
Authors: Cieślak Agnieszka 
Published: April 2021

Abstract
Bronisław Mirski (b. 1887 as Moszkowicz in Żyrardów near Warsaw, Poland – d. 1927 in El Paso, Texas) belongs to the substantial group of Polish émigré artists of Jewish origin. A violinist and conductor educated in Europe, he permanently settled in the United States at the end of 1914 under the name of Nek Mirskey and soon began working as a music director in movie theatres. He was in charge of the musical settings for elaborate artistic programmes composed of silent films as well as music and stage attractions. His first widely acclaimed shows were presented at the Metropolitan Theatre of Harry M. Crandall's chain in Washington, D.C. Based primarily on the American press of 1921–23, this article discusses Mirski's work methods and his involvement in improving the quality of live musical accompaniment for silent films. The work that he continued till the end of his life places him among the foremost musicians of the silent film era.
Promoting an Active Life Through Threatening Communication: Effects on College Student’s Emotions
Authors: Carrasco Luis , Jiménez-Roldán Manuel Jesus , Sañudo Borja , Riquelme José M , Martínez-Díaz Inmaculada C 
Published: April 2021

This pilot study was aimed to evaluate the acute effects of a sedentary-focused intervention through threatening communication on college student’s emotions. Thirty-six female college students (mean age 20.8  2.7 years) who participated voluntarily where exposed to five neutral and five sedentary-related threatening video messages. In order to evaluate the emotional impact of the messages, the subjects’ faces were recorded and analyzed during these expositions using a facial expression recognition software (Face Reader System 4.0), and assessing the time-lapse percentage of the following basic expressions: neutral, sad, angry, surprised, scared, and disgusted. Compared to the neutral messages, a non-significant increase in sad, angry, and disgusted expressions were observed after threatening intervention; nevertheless, the effect size (d) for the disgusted expression was .832. Moreover, the time-lapse percentage of neutral facial expression decreased after threatening messages although no statistical significance was reached (p = .174).
La critique environnementale dans les récits animaliers de René Maran
Authors: Milanesio Lia 
Published: April 2021

This article aims at analysing René Maran’s five animal novels. In these texts, Maran criticizes the colonial system not only for its cruelty to the native population, but also for its ecological violence against the bush and its non-human inhabitants. In particular, this research will be focusing on the author’s ability to abandon a human (and colonial) point of view in order to adopt an animal one. On the one hand, this new subjectivity – as well as Maran’s comprehension of indigenous naturalist society – allows the writer to condemn the colonial period from an ecocritical perspective. On the other hand, it provides evidence of the existence of culture among the beasts of his novels. Finally, this article will also prove that it is thanks to their culture that Maran’s animals will try to resist the colonial-centred environment and ideology.
Confinement et comportements alimentaires
Authors: François-Lecompte Agnès , Innocent Morgane , Kréziak Dominique , Prim-Allaz Isabelle 
Published: April 2021

La première phase de confinement de 2020 semble avoir été l’occasion d’une réflexion sur les modes de vie et de changement dans les pratiques quotidiennes. Par le processus d’immersion, il s’agit ici d’étudier l’impact du confinement sur les pratiques alimentaires durables. L’analyse menée sur trois collectes de données permet de montrer des profils d’évolution des pratiques alimentaires. Le confinement a notamment généré une alimentation plus durable pour 30 % des répondants, essentiellement du fait d’une augmentation des achats de produits locaux et de saison.
QUALITATIVE ANALYSIS OF THE INFORMATION OF HEALTHCARE PROFESSIONALS WORKING IN PEDIATRICS UNITS ON CHILDREN'S RIGHTS
Authors: KOÇ ÖZKAN Tuba , YILDIRIM Maksude , BUCAK İbrahim , ALMIŞ Habip 
Published: April 2021

Abstract: It is important for health professionals working with children to be aware of all aspects of children’s rights. the research was conducted to determine the qualitative analysis of the knowledge of the healthcare professionals working in pediatrics units on children's rights. Twenty health workers in the pediatric units of an obstetric and children’s hospital, nine physicians and eleven nurses, took part in the research. Data were collected with the semi-structured interview technique using an ‘Information Form’ and an ‘Structured Interview Form.’ Data were then subjected to analysis. Two themes were determined as "the views of healthcare professionals on children's rights" and "What can be done to better implement children's rights". In line with these themes; It was determined that healthcare workers mostly focused on children's right to life and development, and other rights were not mentioned much. It was determined that healthcare professionals thought that training should be given to raise awareness on children's rights. It is recommended that in-service training be provided to increase the knowledge and awareness of children’s rights among health workers in pediatric units.
Key words: Child; Children’s Rights; Nurse; Physician
Comparison of Pregnancy and Neonatal Outcomes of Single Frozen Blastocyst Transfer Between Letrozole-Induction and HRT Cycles in Patients With Abnormal Ovulation
Authors: Zhang Junwei , Li Zhen , Sun Lijun , Guan Yichun , Du Mingze 
Published: April 2021

BackgroundThe use of frozen embryo transfer (FET) cycles has dramatically risen. The optimal endometrial preparation method for women undergoing FET is of utmost importance to provide the optimal chances of pregnancy. For patients with abnormal ovulation in particular, there have been few studies on FET protocols; notably, most of these studies focus only on the clinical pregnancy rate or live birth rate (LBR) and pay little attention to the regimen’s safety for offspring.MethodsIt was a retrospective cohort study. First FET cycle with a single blastocyst from whole embryo frozen IVF/ICSI at the Reproductive Center of Third Affiliated Hospital of Zhengzhou University between January 2016 and January 2020. The LBR was the primary outcome of interest. The secondary outcome measures were miscarriage rate and offspring safety, including preterm birth, low birthweight (LBW), small-for-gestational age (SGA), macrosomia and large-for-gestational age (LGA).ResultsIn total, 2782 FET cycles met the eligibility criteria for analysis. Additionally, there were 1178 singleton births from FET cycles. The clinical pregnancy rate was 58.4% in the L-FET group and 54.5% in the HRT group, with no statistical significance (P=.116). The miscarriage rate was higher in the HRT group than in the L-FET group (21.7% vs. 14.3%, P=.005). The LBR was significantly higher in the L-FET group than in the HRT group (49.6% vs. 41.7%, P=.001). Neonatal outcomes were similar between the two groups. After adjustments for confounding factors, the LBR was higher in the L-FET group (aOR 1.30, 95% CI 1.06-1.58). The rate of miscarriage was lower in the L-FET group (aOR 0.63, 95% CI 0.44-0.90).ConclusionFor patients with abnormal ovulation, the L-FET regimen has a higher LBR and lower miscarriage rate than HRT. The neonatal outcomes were similar between the two groups.
Case Report: Extended Clinical Spectrum of the Neonatal Diabetes With Congenital Hypothyroidism Syndrome
Authors: Splittstoesser Vera , Vollbach Heike , Plamper Michaela , Garbe Werner , De Franco Elisa , Houghton Jayne A. L. , Dueker Gesche , Ganschow Rainer , Gohlke Bettina , Schreiner Felix 
Published: April 2021

BackgroundNeonatal diabetes with congenital hypothyroidism (NDH) syndrome is a rare condition caused by homozygous or compound heterozygous mutations in the GLI-similar 3 coding gene GLIS3. Almost 20 patients have been reported to date, with significant phenotypic variability.Case presentationWe describe a boy with a homozygous deletion (exons 5-9) in the GLIS3 gene, who presents novel clinical aspects not reported previously. In addition to neonatal diabetes, congenital hypothyroidism and other known multi-organ manifestations such as cholestasis and renal cysts, he suffered from hyporegenerative anemia during the first four months of life and presents megalocornea in the absence of elevated intraocular pressure. Compensation of partial exocrine pancreatic insufficiency and deficiencies in antioxidative vitamins seemed to have exerted marked beneficial impact on several disease symptoms including cholestasis and TSH resistance, although a causal relation is difficult to prove. Considering reports on persistent fetal hemoglobin detected in a few children with GLIS3 mutations, the transient anemia seen in our patient may represent a further symptom associated with either the GLIS3 defect itself or, secondarily, micronutrient deficiency related to exocrine pancreatic deficiency or cholestasis.ConclusionsOur report expands the phenotypic spectrum of patients with GLIS3 mutations and adds important information on the clinical course, highlighting the possible beneficial effects of pancreatic enzyme and antioxidative vitamin substitutions on characteristic NDH syndrome manifestations such as TSH resistance and cholestasis. We recommend to carefully screen infants with GLIS3 mutations for subtle biochemical signs of partial exocrine pancreatic deficiency or to discuss exploratory administration of pancreatic enzymes and antioxidative vitamins, even in case of good weight gain and fecal elastase concentrations in the low-to-normal range.