bluuebunny/crossref_metadata_2025_split huggingface dataset:
Large magnetoresistance in the iron-free pnictide superconductor LaRu2P2
Authors: Fernández-Lomana Marta , Barrena Víctor , Wu Beilun , Delgado Sara , Mompeán Federico , García-Hernández Mar , Suderow Hermann , Guillamón Isabel 
Published: January 2021

Abstract
The magnetoresistance (MR) of iron pnictide superconductors is often dominated by electron–electron correlations and deviates from the H
2 or saturating behaviors expected for uncorrelated metals. Contrary to similar Fe-based pnictide systems, the superconductor LaRu2P2 (T
c = 4 K) shows no enhancement of electron–electron correlations. Here we report a non-saturating MR deviating from the H
2 or saturating behaviors in LaRu2P2. We present results in single crystals of LaRu2P2, where we observe a MR following H
1.3 up to 22 T. We discuss our result by comparing the bandstructure of LaRu2P2 with that of Fe based pnictide superconductors. The different orbital structures of Fe and Ru leads to a 3D Fermi surface with negligible bandwidth renormalization in LaRu2P2, that contains a large open sheet over the whole Brillouin zone. We show that the large MR in LaRu2P2 is unrelated to the one obtained in materials with strong electron–electron correlations and that it is compatible instead with conduction due to open orbits on the rather complex Fermi surface structure of LaRu2P2.
A novel multifunctional gold nanorod-mediated and tumor-targeted gene silencing of GPC-3 synergizes photothermal therapy for liver cancer
Authors: Liu Yanling , Tan Manman , Fang Chunjuan , Chen Xiaoyan , Liu Huan , Feng Ying , Zhang Yujuan , Min Weiping 
Published: January 2021

Abstract
Tumor-specific targeted delivery is a major obstacle to clinical treatment of hepatocellular carcinoma (HCC). Here we have developed a novel multi-functional nanostructure GAL-GNR-siGPC-3, which consists of Galactose (GAL) as the HCC-targeting moiety, golden nanorods (GNR) as a framework to destroy tumor cells under laser irradiation, and siRNA of Glypican-3 (siGPC-3) which induce specifically gene silence of GPC-3 in HCC. Glypican-3 (GPC-3) gene is highly associated with HCC and is a new potential target for HCC therapy. On the other hand, Gal can specifically bind to the asialoglycoprotein receptor which is highly expressed on membrane of hepatoma cells. GAL and siGPC-3 can induce targeted silencing of GPC-3 gene in hepatoma cells. In vivo and in vitro results showed that GAL-GNR-siGPC-3 could significantly induce downregulation of GPC-3 gene and inhibit the progression of HCC. More notably, GAL-GNR-siGPC-3 could induce both GPC-3 gene silencing and photothermal effects, and the synergistic treatment of tumors was more effective than individual treatments. In summary, GAL-GNR-siGPC-3 achieved a synergistic outcome to the treatment of cancer, which opens up a new approach for the development of clinical therapies for HCC.
Computation of linear MHD instabilities with the multi-region relaxed MHD energy principle
Authors: Kumar A , Qu Z , Hole M J , Wright A M , Loizu J , Hudson S R , Baillod A , Dewar R L , Ferraro N M 
Published: January 2021

Abstract
Over the last decade, a variational principle based on a generalisation of Taylor’s relaxation, referred to as multi-region relaxed magnetohydrodynamics (MRxMHDs) has been developed. The numerical solutions of the MRxMHD equilibria have been constructed using the Stepped Pressure Equilibrium Code (SPEC) (Hudson et al 2012 Phys. Plasmas
19 112502). In principle, SPEC could also be established to describe the MRxMHD stability of an equilibrium. In this work, a theoretical framework is developed to relate the second variation of the energy functional to the so-called Hessian matrix, enabling the prediction of MHD linear instabilities of cylindrical plasmas, and is implemented in SPEC. The negative and positive eigenvalues of the Hessian matrix predict the stability of an equilibrium. Verification studies of SPEC stability results with the M3D-C
1 code and the tearing mode

Δ

′

criterion have been conducted for ideal and resistive MHD instabilities, respectively, in a pressureless cylindrical tokamak, and have shown good agreement. Our stability analysis is a critical step towards understanding the MHD stability of three-dimensional MHDs where nested flux surfaces, magnetic islands and stochastic regions co-exist.
Tungsten impurity effects on the coupling of TEM and ITG mode in reversed magnetic shear tokamak plasmas
Authors: Liu Jiayan , Dong J Q , Du H R , Li J , Wang F , Wang Z X , Han M K , Shen Y 
Published: January 2021

Abstract
The trapped electron mode (TEM) and ion temperature gradient (ITG) mode may couple into one hybrid mode or coexist simultaneously, depending on the regime of tokamak plasma parameters. A gyrokinetic integral eigenvalue equation is applied to investigate the coupling of TEM and ITG mode in the presence of tungsten (W) impurity in tokamak geometry of reversed magnetic shear (RMS). Systematic analysis of W impurity effects on the mode characteristics and induced quasi-linear particle flux has been performed in a wide regime of plasma parameters such as density gradient

L

e
z

=

L

n
e

/

L

n
z

, charge concentration

f
z

, and charge number

Z

of impurity ions, and poloidal wave number

k
θ

ρ
s

spectrum. It is found that both RMS and the impurity ions with inwardly peaked density profile and high charge concentration have strongly stabilizing effects on the modes. Furthermore, the increasing

Z

tends to decouple the hybrid mode into coexisting modes or dominating TEM/ITG mode in different parameter regions. The significance of the results for the particle transport of impurity and main ions as well as electrons in advanced tokamaks with W components is discussed.
Effect of Ag source layer thickness on the switching mechanism of TiN/Ag/SiN
x
/TiN conductive bridging random access memory observed at sub-µA current
Authors: Choi Yeon-Joon , Bang Suhyun , Kim Tae-Hyeon , Lee Dong Keun , Hong Kyungho , Kim Sungjun , Park Byung-Gook 
Published: January 2021

Abstract
Experiments are conducted to compare the resistive switching characteristics for several samples with different amounts of Ag deposition in TiN/Ag/SiN
x
/TiN conductive bridging random access memory (CBRAM). The compliance current in TiN/Ag/SiN
x
/TiN CBRAM determines the volatile/non-volatile memory operation as the current level controls the strength of the filament made of Ag. The transient measurement showed that the effective thickness of Ag source layer in the TiN/Ag/SiN
x
/TiN controls the supply of the Ag atoms into the insulating layer, affecting the strength of the conductive bridge. The mechanism for the switching characteristics and the volatility trend with the amount of Ag deposition is closely investigated using transmission electron microscopy and scanning electron microscopy images. The device shows the conductance potentiation by a voltage pulse train under 1 µA current level, and the higher potentiation rate is observed in the CBRAM with thick Ag source layer.
Selective-area growth study of GaN micropillars for quasi-vertical Schottky diodes
Authors: Debald A , Kotzea S , Ahmadsad H , Heuken M , Kalisch H , Vescan A 
Published: January 2021

Abstract
In this work, metal organic vapor phase epitaxy (MOVPE) is employed for selective-area growth (SAG) of undoped and lightly n-doped GaN micropillars on masked GaN-on-sapphire templates. In micropillar geometry, the limits of GaN drift layer thickness in hetereoepitaxial Schottky diodes are expected to be significantly pushed upwards. This is an important step towards the realization of GaN-based quasi-vertical power devices with high breakdown voltage (V
br) on low-cost foreign substrates. Micropillar growth evolution and the impact of growth rate and V/III ratio on micropillar morphology and parasitic GaN deposition on AlOx hard masks are investigated. By using a combination of low growth rate and high V/III ratio, 12–22 µm high micropillars with planar pillar tops are grown in circular mask openings with radii of 35–100 µm. The threading dislocation density of the highest pillars is (1.4 ± 0.3) × 107 cm−2. Schottky diodes on micropillars with lowest net doping concentration (N
D − N
A) of 1.3 × 1016 cm−3 exhibit excellent forward characteristics with ideality factors

n
<
1.10

, on/off-ratios up to 1010, and on-resistances R

on

<

1 m

Ω

cm−2.
Smart wearable monitoring system based on multi-type sensors for motion recognition
Authors: Yang Jiehua , Li Qiao , Wang Xi , Di Ping , Ding Hao , Bai Yunfeng , Dong Weiwei , Zhu Shigen 
Published: January 2021

Abstract
Motion monitoring systems are often designed and researched to detect the movement of human lower limbs, and play an important role in the field of exoskeleton control. However, current wearable devices can still be improved to be more convenient or accurate in motion recognition. In this work, a comfortable smart wearable gait monitoring system was designed and tested. Inertial measurement units (IMUs) and flexible membrane compression sensors were implemented, integrated to a comfortable sport pant and insoles of both feet, respectively. Data acquisition module was designed, while software with user interface for data collection and storage was realized based on LABVIEW. Experiments were conducted to evaluate the recognition performance of the smart wearable gait monitoring system among nine common actions. Results show that the combined data set of IMUs and compression sensor provided by the system can highly improve classification performance. Based on the self-designed sensing network and the K-nearest neighbor machine learning algorithm, the recognition rate of nine motion patterns can reach as high as 99.96%, showing that the multi-channel wearable gait monitoring system is more effective for motion detection and prediction compared to that with single-type sensors.
Power law decay of stored pattern stability in sparse Hopfield neural networks
Authors: Fang Fei , Yang Zhou , Wang Sheng-Jun 
Published: January 2021

Abstract
Hopfield neural networks on scale-free networks display the power law relation between the stability of patterns and the number of patterns. The stability is measured by the overlap between the output state and the stored pattern which is presented to a neural network. In simulations the overlap declines to a constant by a power law decay. Here we provide the explanation for the power law behavior through the signal-to-noise ratio analysis. We show that on sparse networks storing a plenty of patterns the stability of stored patterns can be approached by a power law function with the exponent −0.5. There is a difference between analytic and simulation results that the analytic results of overlap decay to 0. The difference exists because the signal and noise term of nodes diverge from the mean-field approach in the sparse finite size networks.
Performance test and analysis of the first large-scale cable-in-conduit conductor with high J
c Nb3Sn strand for fusion reactor
Authors: Dai Chao , Wu Yu , Li Jiangang , Guo Zichuan , Qin Jinggang , Long Feng , Nijhuis Arend , Bruzzone Pierluigi , Stepanov Boris , Shi Yi , Liu Sheng , Zhang Yongliang , Derevd Arnaud , Xiang Binglun 
Published: January 2021

Abstract
The Comprehensive Research Facility for Fusion Technology (CRAFT) project has been launched in 2019, for developing the essential engineering technologies for Chinese Fusion Engineering Testing Reactor (CFETR). Within this project, a full-size toroidal field (TF) coil will be built as the prototype coil for CFETR. Based on design of CFETR magnet system, the TF coil will operate at 95.6 kA in a peak field of 14.5 T. The high-J
c Nb3Sn strand is taken into consideration due to the critical current density of ITER-grade Nb3Sn is too low at 14.5 T. Considering that it will be the first time to apply the high-J
c Nb3Sn strand in the large-scale cable-in-conduit conductor (CICC) for fusion magnet, a conductor sample made of high-J
c Nb3Sn strand with short twist pitch (STP) cable pattern was manufactured in ASIPP and tested in SULTAN facility, to investigate the feasibility. The test campaign focuses on the impact of cyclic electromagnetic (EM) loading and warm-up cool-down (WUCD) to the performance of the conductor, the strain distribution of the conductor before and after EM cycles was measured by inductive method to make a deeper insight of the conductor performance evolution. AC losses tests have also been carried out, providing relevant information for further coil design.
Quantum nanostructures for plasmonics and high refractive index photonics
Authors: Toudert Johann 
Published: January 2021

Abstract
Although plasmonics and high refractive index photonics have experienced very fast growth thanks to classical physics concepts, there is an increasing interest in harnessing quantum physics concepts for further pushing the frontiers of these fields. In this context, this perspective highlights the importance of some quantum nanostructures for building nanomaterials and metamaterials with enhanced plasmonic and high refractive index properties. Two types of nanostructures displaying quantum properties are considered: (a) quantum confined nanostructures consisting of noble metals or standard semiconductors, (b) nanostructures built from alternative materials whose dielectric function and optical properties are driven by (possibly tailored) giant interband electronic transitions. A special emphasis is made on the potential of this latter type of nanostructures for achieving outstanding effects for applications, such as ultrabroadband light harvesting, giant refractive index, coupling between dielectric, low-loss plasmonic and magnetic properties, compositionally or externally tuneable optical response. Possible future developments to the field are discussed.
Comparative study between pure and manganese doped copper sulphide (CuS) nanoparticles
Authors: Tailor Jiten P , Chaki S H , Deshpande M P 
Published: January 2021

Abstract
The pure CuS and Mn2+ doped CuS nanoparticles are synthesized by wet chemical route. The CuS phase and hexagonal crystal structure is confirmed by the powder X-ray diffraction and Raman analysis. The vibrational bonds present in the respective synthesized samples are confirmed by Fourier transformed infra-red spectroscopy. The spherical shapes of the nanoparticles are validated by the electron diffraction in scanning and transmission mode. The thermal analysis showed the Mn2+ doped CuS nanoparticles to be more stable than pure CuS nanoparticles. The thermal parameters determined using Coats-Redfern relation stated thermal activation energy and enthalpy change values are highest in the higher temperature range. The Seebeck coefficient variation with temperature and ambient condition Hall effect measurements showed the synthesized nanoparticles to be semiconducting and p-type in nature. The magnetic properties study by Gouy method showed the nanoparticles to be paramagnetic.
SWOTein: a structure-based approach to predict stability Strengths and Weaknesses of prOTEINs
Authors: Hou Qingzhen , Pucci Fabrizio , Ancien François , Kwasigroch Jean Marc , Bourgeas Raphaël , Rooman Marianne 
Published: January 2021

Abstract

Motivation
Although structured proteins adopt their lowest free energy conformation in physiological conditions, the individual residues are generally not in their lowest free energy conformation. Residues that are stability weaknesses are often involved in functional regions, whereas stability strengths ensure local structural stability. The detection of strengths and weaknesses provides key information to guide protein engineering experiments aiming to modulate folding and various functional processes.

Results
We developed the SWOTein predictor which identifies strong and weak residues in proteins on the basis of three types of statistical energy functions describing local interactions along the chain, hydrophobic forces and tertiary interactions. The large-scale analysis of the different types of strengths and weaknesses demonstrated their complementarity and the enhancement of the information they provide. Moreover, a good average correlation was observed between predicted and experimental strengths and weaknesses obtained from native hydrogen exchange data. SWOTein application to three test cases further showed its suitability to predict and interpret strong and weak residues in the context of folding, conformational changes and protein-protein binding. In summary, SWOTein is both fast and accurate and can be applied at small and large scale to analyze and modulate folding and molecular recognition processes.

Availabilityand implementation
The SWOTein webserver provides the list of predicted strengths and weaknesses and a protein structure visualization tool that facilitates the interpretation of the predictions. It is freely available for academic use at http://babylone.ulb.ac.be/SWOTein/.

Supplementary information
Supplementary data are available at Bioinformatics online.
Open versus laparoscopic incisional hernia repair: nationwide database study
Authors: Henriksen N A , Friis-Andersen H , Jorgensen L N , Helgstrand F 
Published: January 2021

Abstract

Background
Although laparoscopic repair of incisional hernias decreases the incidence of wound complications compared with open repair, there has been rising concern related to intraperitoneal mesh placement. The aim of this study was to examine outcomes after open or laparoscopic elective incisional hernia mesh repair on a nationwide basis.

Methods
This study analysed merged data from the Danish Hernia Database and the National Patient Registry on perioperative information, 90-day readmission, 90-day reoperation for complication, and long-term operation for hernia recurrence among patients who underwent primary repair of an incisional hernia between 2007 and 2018.

Results
A total of 3090 (57.5 per cent) and 2288 (42.5 per cent) patients had surgery by a laparoscopic and open approach respectively. The defect was closed in 865 of 3090 laparoscopic procedures (28.0 per cent). The median follow-up time was 4.0 (i.q.r. 1.8–6.8) years. Rates of readmission (502 of 3090 (16.2 per cent) versus 442 of 2288 (19.3 per cent); P = 0.003) and reoperation for complication (216 of 3090 (7.0 per cent) versus 288 of 2288 (12.5 per cent); P &lt; 0.001) were significantly lower for laparoscopic than open repairs. Reoperation for bowel obstruction or bowel resection was twice as common after laparoscopic repair compared with open repair (20 of 3090 (0.6 per cent) versus 6 of 2288 (0.3 per cent); P = 0.044). Patients were significantly less likely to undergo repair of recurrence following laparoscopic compared with open repair of defect widths 2–6 cm (P = 0.002).

Conclusion
Laparoscopic intraperitoneal mesh repair for incisional hernia should still be considered for fascial defects between 2 and 6 cm, because of decreased rates of early complications and repair of hernia recurrence compared with open repair.
Odor–Taste Interactions in Food Perception: Exposure Protocol Shows No Effects of Associative Learning
Authors: Fondberg Robin , Lundström Johan N , Seubert Janina 
Published: January 2021

Abstract
Repeated exposure can change the perceptual and hedonic features of flavor. Associative learning during which a flavor’s odor component is affected by co-exposure with taste is thought to be central in this process. However, changes can also arise due to exposure to the odor in itself. The aim of this study was to dissociate effects of associative learning from effects of exposure without taste by repeatedly presenting one odor together with sucrose and a second odor alone. Sixty individuals attended two testing sessions separated by a 5-day Exposure Phase during which the stimuli were presented as flavorants in chewing gums that were chewed three times daily. Ratings of odor sweetness, odor pleasantness, odor intensity enhancement by taste, and odor referral to the mouth were collected at both sessions. Consistent with the notion that food preferences are modulated by exposure, odor pleasantness increased between the sessions independently of whether the odor (basil or orange flower) had been presented with or without sucrose. However, we found no evidence of associative learning in any of the tasks. In addition, exploratory equivalence tests suggested that these effects were either absent or insignificant in magnitude. Taken together, our results suggest that the hypothesized effects of associative learning are either smaller than previously thought or highly dependent on the experimental setting. Future studies are needed to evaluate the relative support for these explanations and, if experimental conditions can be identified that reliably produce such effects, to identify factors that regulate the formation of new odor–taste associations.
Cardiac Remodeling and Hypertension in HIV-Uninfected Infants Exposed in utero to Antiretroviral Therapy
Authors: García-Otero Laura , López Marta , Goncé Anna , Fortuny Claudia , Salazar Laura , Valenzuela-Alcaraz Brenda , Guirado Laura , César Sergi , Gratacós Eduard , Crispi Fátima 
Published: January 2021

Abstract

Background
We aimed to assess the postnatal pattern of cardiovascular remodeling associated with intrauterine exposure to maternal HIV and antiretroviral treatment (ART).

Methods
Prospective cohort including 34 HIV-exposed uninfected (HEU) infants and 53 non-HIV-exposed infants were evaluated from fetal life up to 6 months postnatally. A cardiovascular evaluation was performed including echocardiography, blood pressure, and carotid intima media thickness (cIMT) measurement.

Results
ART regimens during pregnancy included 2 nucleoside reverse transcriptase inhibitors (Abacavir + Lamivudine (32.4%), Emtricitabine + Tenofovir (41.2%), and Zidovudine + Lamivudine (20.6%)). At 6 months of age, HIV-exposed uninfected infants showed thicker myocardial walls (septal wall thickness mean 5.02 mm (SD 0.85) vs 3.98 mm (0.86); P &lt; .001), relative systolic dysfunction with decreased mitral ring displacement (8.57 mm (2.03) vs 10.34 mm (1.84); P = .002), and decreased tricuspid S’ (9.71 cm/s (1.94) vs 11.54 cm/s (2.07); P = .003) together with relative diastolic dysfunction showed by prolonged left isovolumic relaxation time (58.57 ms (13.79) vs 47.94 (7.39); P &lt; .001). Vascular assessment showed significantly higher systolic and diastolic blood pressure (102 mmHg (16.1) vs 80 mmHg (13.9); P &lt; .001 and 64 mmHg (14.4) vs 55 mmHg (10.2); P = .045 respectively), with 50% of HIV-exposed children meeting criteria for hypertension vs 3.77% of the non-HIV-exposed group (P &lt; .001) and thicker mean cIMT in the HIV-exposed group (0.62 µm (0.09) vs 0.51 µm (0.09); P = .015).

Conclusions
Subclinical cardiac impairment together with higher blood pressure and thicker cIMT were observed in HIV-exposed infants at 6 months of age. Half of them presented hypertension. Our findings support a possible increased cardiovascular risk in HIV uninfected infants exposed in utero to ART.
Treatment for severe COVID-19 with a biomimetic sorbent haemoperfusion device in patients on haemodialysis
Authors: Sandoval Diego , Rama Inés , Quero María , Hueso Miguel , Gómez Francisco , Cruzado Josep M 
Published: January 2021

AbstractHaemodialysis (HD) patients present more morbidity and mortality risk in coronavirus disease 2019 (COVID-19). In patients who may develop severe symptoms, the process called ‘viral sepsis’ seems to be a crucial mechanism. In those cases, the HD procedure provides an excellent tool to explore the benefit of some extracorporeal therapies. We reported the outcome of four HD patients with severe COVID-19 treated with Seraph®100 haemoperfusion (HP) device. Three of the four cases presented a good clinical response after HP. In conclusion, the treatment with Seraph®100 device may be a simultaneous treatment to improve HD patients with severe acute respiratory syndrome coronavirus 2.