bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ecological opportunity and adaptive radiations reveal eco-evolutionary perspectives on community structure in competitive communities
Authors: Pontarp Mikael 
Published: October 2021

AbstractIt is well known that ecological and evolutionary processes act in concert while shaping biological communities. Diversification can, for example, arise through ecological opportunity and adaptive radiations and competition play an essential role in such diversification. Eco-evolutionary components of competition are thus important for our understanding of community assembly. Such understanding in turn facilitates interpretation of trait- and phylogenetic community patterns in the light of the processes that shape them. Here, I investigate the link between competition, diversification, and trait- and phylogenetic- community patterns using a trait-based model of adaptive radiations. I evaluate the paradigm that competition is an ecological process that drives large trait- and phylogenetic community distances through limiting similarity. Contrary to the common view, I identify low or in some cases counterintuitive relationships between competition and mean phylogenetic distances due to diversification late in evolutionary time and peripheral parts of niche space when competition is weak. Community patterns as a function of competition also change as diversification progresses as the relationship between competition and trait similarity among species can flip from positive to negative with time. The results thus provide novel perspectives on community assembly and emphasize the importance of acknowledging eco-evolutionary processes when interpreting community data.
Viral detection and identification in 20 min by rapid single-particle fluorescence in-situ hybridization of viral RNA
Authors: Hepp Christof , Shiaelis Nicolas , Robb Nicole C. , Vaughan Alison , Matthews Philippa C. , Stoesser Nicole , Crook Derrick , Kapanidis Achillefs N. 
Published: October 2021

AbstractThe increasing risk from viral outbreaks such as the ongoing COVID-19 pandemic exacerbates the need for rapid, affordable and sensitive methods for virus detection, identification and quantification; however, existing methods for detecting virus particles in biological samples usually depend on multistep protocols that take considerable time to yield a result. Here, we introduce a rapid fluorescence in situ hybridization (FISH) protocol capable of detecting influenza virus, avian infectious bronchitis virus and SARS-CoV-2 specifically and quantitatively in approximately 20 min, in virus cultures, combined nasal and throat swabs with added virus and likely patient samples without previous purification. This fast and facile workflow can be adapted both as a lab technique and a future diagnostic tool in enveloped viruses with an accessible genome.
Vitamin D in pediatric patients with obesity and arterial hypertension
Authors: Radulović Živa , Zupan Zarja Polak , Tomazini Aljoša , Varda Nataša Marčun 
Published: October 2021

AbstractThe purpose of this study was to find potential differences in vitamin D levels between different groups: overweight children with hypertension, normal-weight children with hypertension, overweight children with normal blood pressure and normal-weight children without hypertension, representing the control group. We also wanted to determine whether there are correlations between vitamin D levels and other clinical laboratory parameters, to evaluate the potential need for substitution. We measured vitamin D, homocysteine, total cholesterol, HDL, LDL, triglycerides, uric acid, glucose, apolipoprotein A1, apolipoprotein B, alkaline phosphatase, calcium, phosphate and magnesium serum levels in all groups. We also took anthropometric measurements (body weight, height, body mass index (BMI)) and observed patients’ blood pressure. The results were analyzed with SPSS statistic tool with basic statistical methods. The study included 175 children between 5 and 18 years of age. Fiftyseven were healthy (group A—control group), 41 normal-weight with hypertension (group B), 44 overweight with hypertension (group C) and 33 overweight with normal blood pressure (group D). The results showed statistically significant differences in values of vitamin D between all groups—A and B (p = 0.003), A and C (p < 0.001), A and D (p < 0.001), B and D (p = 0.043), B and C (0.030), except for groups C and D (p = 0.830). There were statistically significant correlations between vitamin D and BMI (r = − 0.196, p = 0.010), systolic pressure (r = − 0.190, p = 0.002), diastolic pressure (r = − 0.149, p = 0.050), homocysteine (r = − 0.208, p = 0.007), triglycerides (r = − 0.196, p = 0.011) and apolipoprotein A1 (r = 0.222, p = 0.007), confirmed in multivariate model. For the blood pressure, the higher the systolic blood pressure, the lower the average vitamin D was. The pilot study shows significant differences in serum vitamin D levels between all groups of children, apart from groups C and D. These results, combined with statistically significant correlations between vitamin D and systolic and diastolic blood pressure suggest the need for monitoring and potential substitution of vitamin D in in pediatric patients with hypertension.
Kinetic arrest of the ferromagnetic state in Mn$$_3$$GaC and Ni$$_2$$MnGa composite mixtures
Authors: Priolkar K. R. , Nevgi R. , Dias E. T. , Nigam A. K. 
Published: October 2021

AbstractThe kinetics of the ferromagnetic to antiferromagnetic transition in Mn$$_3$$

3

GaC can be arrested and its magnetic properties can be tuned by mixing a small amount ($$\sim $$
∼
10%) of Heusler Ni$$_2$$

2

MnGa to Mn$$_3$$

3

GaC. A detailed study of magnetic properties of composite mixtures of Mn$$_3$$

3

GaC and Ni$$_2$$

2

MnGa with different antiperovskite to Heusler ratio, reveals that the ferromagnetic Ni$$_2$$

2

MnGa polarizes magnetic spins of the antiperovskite phase by creating a magnetic strain field in its vicinity. The Heusler phase acts as a defect centre whose influence on the magnetic properties of the majority antiperovskite phase progressively diminishes, creating a distribution of transition temperatures. Such strong interaction between the two phases of the mixture allows for tunability and control over the properties of such magneto-structurally transforming materials.
Novel reusable hydrogel adsorbents for precious metal recycle
Authors: Dharmapriya Thakshila N. , Lee Ding-Yang , Huang Po-Jung 
Published: October 2021

AbstractA novel polyethylene glycol diacrylate-allylthiourea (ATU-PEGDA) hydrogel was simply synthesized through photo-reaction. Modified thiourea simultaneously employed chelation and electrostatic force to selectively recycle Ag(I) and Pd(II) from electrolytic wastewater. Sorption efficiency was nearly 100% for Ag(I) and Pd(II), which occurred at initial pH of 1 within 300 min. The adsorption characteristics of ATU-PEGDA followed Langmuir isotherm model and the maximum adsorption capacity of Ag(I) and Pd(II) achieved 83.33 and 152.81 mg g−1 sorbent, respectively where Pseudo-first order model demonstrate the adsorption kinetics. In the presence of other heavy metals, ATU-PEGDA performed high selectivity, 0.89 and 1.31 towards Ag(I) and Pd(II). ATU-PEGDA can be completely regenerated within 120 min using 0.5 M thiourea—0.001 M HNO3 and 1 M thiourea—4 M HCl after the adsorption of Ag(I) and Pd(II), respectively. Thiourea-branched structure was created after regeneration, improving the adsorption capacity. Compared to initial hydrogel, the adsorption capacity of Ag(I) and Pd(II) increased 31.83 ± 3.08% and 75.12 ± 11.02%, respectively. Over 10 consecutive adsorption–desorption cycles, ATU-PEGDA performed 111.34 and 263.79 mg g−1 sorbent in adsorption capacity of Ag(I) and Pd(II). Chromism of ATU-PEGDA hydrogel was a benefit to determine adsorption saturation and completely desorption of Ag(I) and Pd(II). Potentially, ATU-PEGDA can be extended to industrial applications.
Soft surfaces promote astrocytic differentiation of mouse embryonic neural stem cells via dephosphorylation of MRLC in the absence of serum
Authors: Oyama Hiroshi , Nukuda Akihiro , Ishihara Seiichiro , Haga Hisashi 
Published: October 2021

AbstractAstrocytes, which can be obtained from neural stem cells (NSCs) by adding serum and/or recombinant proteins in culture media or by passaging NSCs repeatedly, are expected to be applicable in regenerative medicine for the treatment of neurodegenerative diseases. However, astrocytes obtained using existing methods are costly and have poor quality. The stiffness of culture surfaces has been reported to affect astrocytic differentiation of adult NSCs. However, the influence of surface stiffness on astrocytic differentiation of embryonic NSCs has not yet been reported. In this study, we showed that astrocytic differentiation of embryonic NSCs was increased on soft surfaces (1 kPa and 12 kPa) compared with the NSCs on stiff surfaces (2.8 GPa) in serum-free condition. Furthermore, di-phosphorylated myosin regulatory light chain (PP-MRLC) was decreased in embryonic NSCs cultured on the soft surfaces than the cells on the stiff surfaces. Additionally, astrocytic differentiation of embryonic NSCs was induced by a Ras homolog associated kinase (ROCK) inhibitor, which decreased PP-MRLC in NSCs. These results suggest that decreasing the PP-MRLC of embryonic NSCs on soft surfaces or treating NSCs with a ROCK inhibitor is a good method to prepare astrocytes for application in regenerative medicine.
The tiny effects of respiratory masks on physiological, subjective, and behavioral measures under mental load in a randomized controlled trial
Authors: Spang Robert P. , Pieper Kerstin 
Published: October 2021

AbstractSince the outbreak of the coronavirus disease (COVID-19), face coverings are recommended to diminish person-to-person transmission of the SARS-CoV-2 virus. Some public debates concern claims regarding risks caused by wearing face masks, like, e.g., decreased blood oxygen levels and impaired cognitive capabilities. The present, pre-registered study aims to contribute clarity by delivering a direct comparison of wearing an N95 respirator and wearing no face covering. We focused on a demanding situation to show that cognitive efficacy and individual states are equivalent in both conditions. We conducted a randomized-controlled crossover trial with 44 participants. Participants performed the task while wearing an N95 FFR versus wearing none. We measured physiological (blood oxygen saturation and heart rate variability), behavioral (parameters of performance in the task), and subjective (perceived mental load) data to substantiate our assumption as broadly as possible. We analyzed data regarding both statistical equivalence and differences. All of the investigated dimensions showed statistical equivalence given our pre-registered equivalence boundaries. None of the dimensions showed a significant difference between wearing an FFR and not wearing an FFR.Trial Registration: Preregistered with the Open Science Framework: https://osf.io/c2xp5 (15/11/2020). Retrospectively registered with German Clinical Trials Register: DRKS00024806 (18/03/2021).
Intelligent computing technique based supervised learning for squeezing flow model
Authors: Almalki Maryam Mabrook , Alaidarous Eman Salem , Maturi Dalal Adnan , Raja Muhammad Asif Zahoor , Shoaib Muhammad 
Published: October 2021

AbstractIn this study, the unsteady squeezing flow between circular parallel plates (USF-CPP) is investigated through the intelligent computing paradigm of Levenberg–Marquard backpropagation neural networks (LMBNN). Similarity transformation introduces the fluidic system of the governing partial differential equations into nonlinear ordinary differential equations. A dataset is generated based on squeezing fluid flow system USF-CPP for the LMBNN through the Runge–Kutta method by the suitable variations of Reynolds number and volume flow rate. To attain approximation solutions for USF-CPP to different scenarios and cases of LMBNN, the operations of training, testing, and validation are prepared and then the outcomes are compared with the reference data set to ensure the suggested model’s accuracy. The output of LMBNN is discussed by the mean square error, dynamics of state transition, analysis of error histograms, and regression illustrations.
Co-contraction of ankle muscle activity during quiet standing in individuals with incomplete spinal cord injury is associated with postural instability
Authors: Fok Kai Lon , Lee Jae W. , Unger Janelle , Chan Katherine , Musselman Kristin E. , Masani Kei 
Published: October 2021

AbstractPrevious findings indicate that co-contractions of plantarflexors and dorsiflexors during quiet standing increase the ankle mechanical joint stiffness, resulting in increased postural sway. Balance impairments in individuals with incomplete spinal cord injury (iSCI) may be due to co-contractions like in other individuals with reduced balance ability. Here we investigated the effect of co-contraction between plantar- and dorsiflexors on postural balance in individuals with iSCI (iSCI-group) and able-bodied individuals (AB-group). Thirteen able-bodied individuals and 13 individuals with iSCI were asked to perform quiet standing with their eyes open (EO) and eyes closed (EC). Kinetics and electromyograms from the tibialis anterior (TA), soleus and medial gastrocnemius were collected bilaterally. The iSCI-group exhibited more co-contractions than the AB-group (EO: 0.208% vs. 75.163%, p = 0.004; EC: 1.767% vs. 92.373%, p = 0.016). Furthermore, postural sway was larger during co-contractions than during no co-contraction in the iSCI-group (EO: 1.405 cm/s2 vs. 0.867 cm/s2, p = 0.023; EC: 1.831 cm/s2 vs. 1.179 cm/s2, p = 0.030), but no differences were found for the AB-group (EO: 0.393 cm/s2 vs. 0.499 cm/s2, p = 1.00; EC: 0.686 cm/s2 vs. 0.654 cm/s2, p = 1.00). To investigate the mechanism, we performed a computational simulation study using an inverted pendulum model and linear controllers. An increase of mechanical stiffness in the simulated iSCI-group resulted in increased postural sway (EO: 2.520 cm/s2 vs. 1.174 cm/s2, p < 0.001; EC: 4.226 cm/s2 vs. 1.836 cm/s2, p < 0.001), but not for the simulated AB-group (EO: 0.658 cm/s2 vs. 0.658 cm/s2, p = 1.00; EC: 0.943 cm/s2 vs. 0.926 cm/s2, p = 0.190). Thus, we demonstrated that co-contractions may be a compensatory strategy for individuals with iSCI to accommodate for decreased motor function, but co-contractions may result in increased ankle mechanical joint stiffness and consequently postural sway.
Recurrence-associated gene signature in patients with stage I non-small-cell lung cancer
Authors: Cho Su Han , Yoon Shinkyo , Lee Dae Ho , Kim Sang-We , Kim Kwoneel 
Published: October 2021

AbstractRecurrent gene mutations and fusions in cancer patients are likely to be associated with cancer progression or recurrence by Vogelstein et al. (Science (80-)340, 1546–1558 (2013)). In this study, we investigated gene mutations and fusions that recurrently occurred in early-stage cancer patients with stage I non-small-cell cancer (NSCLC). Targeted exome sequencing was performed to profile the variants and confirmed their fidelity at the gene and pathway levels through comparison with data for stage I lung cancer patients, which was obtained from The Cancer Genome Atlas (TCGA). Next, we identified prognostic gene mutations (ATR, ERBB3, KDR, and MUC6), fusions (GOPC-ROS1 and NTRK1-SH2D2A), and VEGF signaling pathway associated with cancer recurrence. To infer the functional implication of the recurrent variants in early-stage cancers, the extent of their selection pattern was investigated, and they were shown to be under positive selection, implying a selective advantage for cancer progression. Specifically, high selection scores were observed in the variants with significantly high risks for recurrence. Taken together, the results of this study enabled us to identify recurrent gene mutations and fusions in a stage I NSCLC cohort and to demonstrate positive selection, which had implications regarding cancer recurrence.
Simulating graphene dynamics in synthetic space with photonic rings
Authors: Yu Danying , Li Guangzhen , Xiao Meng , Wang Da-Wei , Wan Yong , Yuan Luqi , Chen Xianfeng 
Published: October 2021

AbstractPhotonic honeycomb lattices have attracted broad interests for their fruitful ways in manipulating light, which yet hold difficulties in achieving arbitrary reconfigurability and hence flexible functionality due to fixed geometry configurations. Here we theoretically propose to construct the honeycomb lattice in a one-dimensional ring array under dynamic modulations, with an additional synthetic dimension created by connecting the frequency degree of freedom of light. Such a system is highly re-configurable with parameters flexibly controlled by external modulations. Therefore, various physical phenomena associated with graphene including Klein tunneling, valley-dependent edge states, effective magnetic field, as well as valley-dependent Lorentz force can be simulated in this lattice, which exhibits important potentials for manipulating photons in different ways. Our work unveils an alternative platform for constructing the honeycomb lattice in a synthetic space, which holds complex functionalities and could be important for optical signal processing as well as quantum simulation.
Isotope effect on the sublimation curves and binding energies of 12CO and 13CO interstellar ice analogues
Authors: Smith Lucas R. , Gudipati Murthy S. , Smith Rachel L. , Lewis Robert D. 
Published: October 2021

Aims. Understanding the desorption properties and sublimation temperatures of CO is key toward constraining the astrophysical regimes within which CO exists in the gas and ice phases. Previous experimental studies using temperature programmed desorption (TPD) determined the binding energies of 12CO and 13CO without the precision that is necessary to determine the effect of isotopes on these properties, which is required when analyzing astronomical data of CO isotopologues. The purpose of this work is to precisely determine the binding energies of 12CO and 13CO.
Methods. We conducted experiments using temperature interval desorption (TID), which ensures that thermal equilibrium is reached at each temperature, as well as TPD experiments on interstellar analogues of 12CO and 13CO ices.
Results. Sublimation curves show a small but distinct separation between 12CO and 13CO ices. We found that complete sublimation of pure 12CO occurs at 28.9 ± 0.2 K and pure 13CO at 29.0 ± 0.2 K. A systematic difference of 0.1 K was found for 13CO ice compared to 12CO ice under similar desorption conditions, implying that the binding energy in the ice phase for 13CO ice is higher than that of 12CO. Our experimentally derived binding energies were determined through TID to be (12CO–12CO)Eb = (833 ± 5 K) and (13CO–13CO)Eb = (848 ± 6 K). Our results quantitatively show that 13CO is more tightly bound than 12CO in the ice phase, which could have a significant effect on CO isotopic enrichment in astrophysical settings.
Estimating [α/Fe] from Gaia low-resolution BP/RP spectra using the ExtraTrees algorithm
Authors: Gavel Alvin , Andrae René , Fouesneau Morgan , Korn Andreas J. , Sordo Rosanna 
Published: October 2021

Context. Gaia Data Release 3 will contain more than a billion sources with positions, parallaxes, and proper motions. In addition, for hundreds of millions of stars, it will include low-resolution blue photometer (BP) and red photometer (RP) spectra. Obtained by dispersing light with prisms, these spectra have resolutions that are too low to allow us to measure individual spectral lines and bands. However, the combined BP/RP spectra can be used to estimate some stellar properties such as Teff, log g, and [M/H].
Aims. We investigate the feasibility of using the ExtraTrees algorithm to estimate the alpha element to iron abundance ratio [α/Fe] from low-resolution BP/RP spectra.
Methods. To infer [α/Fe] from the spectra, we created regression models using the ExtraTrees algorithm trained on two samples: a set of synthetic spectra and a set of observed spectra from stars that have known [α/Fe] since they have also been observed using the High Efficiency and Resolution Multi-Element Spectrograph (HERMES) as part of the Galactic Archaeology with HERMES survey. We applied each model to the other sample and to a larger observed sample to assess the performance of the models. In addition, we used our models to analyse stars from the Gaia-Enceladus structure.
Results. We find that the model trained on synthetic data has some ability to reconstruct [α/Fe] from synthetic spectra, but little to none when used on observed spectra. The model trained on observed data reconstructs realistic [α/Fe] from observed spectra, but only for cool stars (⪅5000 K) that have the same correlations as in the training sample between [α/Fe] and other properties such as [Fe/H].
Conclusions. Models using the ExtraTrees algorithm can be used to estimate [α/Fe] from low-resolution BP/RP spectra of cool stars. However, they do this by exploiting correlations between [α/Fe] and other parameters, rather than the causal effect of [α/Fe] on the spectrum. Hence, they are unlikely to be useful in studies that attempt to distinguish stars that only differ in [α/Fe].
Der Mut zur Zerbrechlichkeit: Wie man dem Trauma der
Pandemie begegnet und mit einer ungewissen Zeit lebt (Teil 2)
Authors: Castigliego Giuliano 
Published: October 2021

Zusammenfassung Im zweiten Teil meines Textes lege ich
den Fokus auf den mehrstufigen Trauerprozess, welcher uns erlaubt, den durch die
Pandemie verursachten Verlust der Normalität und der Sicherheit
erfolgreich zu verarbeiten. In Begleitung verschiedener literarischen Figuren
werde ich analysieren, was passieren kann, wenn eine dieser Phasen (Leugnen,
Zorn, Verhandeln, Leid, Annahme) nicht gelingt. Schliesslich lege ich dar, wie
der Wiederaufbauprozess gefördert werden kann und welche Konzepte uns
helfen, um unser schwieriges Zusammenleben mit der Unsicherheit zu gestalten.