bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinicomycological pattern of dermatomycosis – A two-year retrospective study in a tertiary care hospital of north India
Authors: Khan Shoaib Mohmad , Farhana Anjum , Amin Umara , Khan Reyaz A 
Published: April 2021

Fungal infections are a growing cause of concern in both hospital and non-hospital settings all over the world. Fungal infections are often characterized by the location of the infection. These may be referred to as superficial, subcutaneous, or systemic, which is also referred to as deep-seated. Dermatomycosis are superficial fungal infections of the skin & or its appendages.This study was undertaken to determine: 1) The predominant dermatophytes and non dermatophytes causing dermatomycosis. 2) The clinicomycological profile of dermatomycosis.641 samples from clinically suspected cases of dermatomycosis including the skin, hair, and nail samples were collected. All the relevant clinical, demographic, and epidemiological details were noted. Samples were then subjected to direct microscopy and fungal culture.Of the total 641 cases, 337 (52.6%) were males and 304 (47.4) were females (Table 1). The most commonly affected age group was 20–39 years (51%). Out of total, 340 (53%) were nail samples, 283 (44.1%) were skin samples, and 18 (2.9%) were hair samples. Onychomycosis was the commonest clinical presentation (48.8%) followed by Scaly skin lesions (13.1%). Moreover, Tinea corporis was seen in 10.3%, Tinea cruris in 5.3% cases. KOH wet mount was performed on all 641 samples with 230 (35.9%) showing positive results. Whereas, 312 (48.7%) were positive by culture. the most common Fungi isolated in our study were Dermatophytes n=154 (49.4%), followed by Non-dermatophyte molds (NDMs) n=93 (29.8%) and Yeasts n=65 (20.8%).A combination of direct microscopy and culture was found to be superior than direct microscopy and culture alone. The recovery of NDMs and yeasts from routine dermatological samples in addition to the usual suspects, dermatophytes, also increases the awareness and suspicion among clinicians and mycologists to look beyond dermatophytes as the lone cause of superficial skin infections. Additionally, given the geographical location of Kashmir valley and its temperate climate with extremely cold winters (November to March) and a relatively milder summer with moderate humidity levels, when compared to the rest of northern Indian states doesn’t make it a suitable environment for fungal infections, more so the superficial mycosis. That said, people at risk are always vulnerable to develop fungal infections.
Universitários praticantes de musculação realizam consumo irregular de macronutrientes ao longo do dia com ingestão predominante de proteínas de fonte animal
Authors: Takai Fábio Yoshio , Andrade Guilherme Moreira , De Oliveira Lívia Costa , De Abreu Wilson César 
Published: April 2021

Introdução: A ingestão de quantidades adequadas de macronutrientes e proteínas de alta qualidade ao longo do dia pode apresentar impacto na recuperação e adaptação muscular induzida pelo treinamento resistido. Objetivo: Avaliar a distribuição da ingestão de macronutrientes e de fontes proteicas em cada refeição realizada por universitários praticantes de musculação. Materiais e Métodos: Foram avaliados 90 universitários praticantes de musculação. A ingestão alimentar foi avaliada utilizando três registros alimentares de 24h. Dois registros alimentares foram coletados durante a semana em dias de treinos e outro no fim de semana, sem treino. Foram determinados o peso, altura e a composição corporal dos participantes. Resultados: Os participantes apresentaram consumo irregular de energia e macronutrientes ao longo do dia, concentrados no almoço e jantar, indicando que essas são as duas principais refeições do dia. O consumo de proteínas de origem animal foi predominante em todas as refeições, com maiores percentuais observados no jantar (80,72%) e na refeição pós-treino (80,87%). Os participantes que realizavam seis treinos por semana apresentaram ingestão de proteínas e energia significativamente maior comparado àqueles que treinavam três ou quatro vezes por semana (p<0,05).Conclusão: conclui-se que os universitários consomem energia e macronutrientes distribuídos de forma irregular ao longo do dia e que as proteínas ingeridas são predominantemente de fontes animais.
O Aconselhamento Psicológico Como Intervenção Para Mães De Crianças Com Paralisia Cerebral
Authors: Arcas de Felippe Thaís Cristina , Pereira Naelly De Sousa , Cunha Elaine Da Silva Dias , Vicente Danubia Torres , Machado Gustavo De Mendonça 
Published: April 2021

O objetivo principal do presente artigo é refletir a intervenção do Aconselhamento Psicológico como prática psicológica possível que deve ser desenvolvida para redução do nível de estresse em mães de crianças com paralisia cerebral. Este artigo é resultado de um trabalho desenvolvido dentro da disciplina de Aconselhamento e Orientação em Psicologia de uma Faculdade de Psicologia no interior de São Paulo. Com base na pesquisa de Mestrado realizada pela professora orientadora do trabalho, temos dados de que as mães de crianças com Paralisia Cerebral apresentam alto nível de estresse, do qual elas não possuem consciência do quanto afetam sua saúde – física e emocional. Além disso, a estratégia de enfrentamento utilizada por estas mães – a religiosidade e espiritualidade – não se mostrou efetiva para redução desse nível de estresse. Foi possível verificar que o mesmo é influenciado por inúmeras outras variáveis e condições, que precisam de outras formas de suporte e enfrentamento para serem elaboradas. A estrutura da intervenção do Aconselhamento Psicológico se apresenta como possível e até ideal para atingir tal objetivo. O atendimento à saúde mental e emocional dessas mães deve ser considerado uma questão de saúde pública, e deve estar inclusa no atendimento oferecido aos filhos.
Funcionamento Psicológico Parental e Controle Glicêmico de Crianças com Diabetes Mellitus Tipo 1: Uma Revisão de Escopo
Authors: Brito Ariane De , Remor Eduardo 
Published: April 2021

Introdução: Pesquisas sobre os cuidados com o tratamento do diabetes tipo 1 (DM1) em crianças demonstraram que fatores relacionados com o funcionamento psicológico parental estão associados com o controle glicêmico do filho com DM1. Objetivo: A presente revisão de escopo objetivou identificar, mapear e discutir as evidências disponíveis acerca das associações existentes entre as variáveis de funcionamento psicológico parental e o controle glicêmico de crianças até dez anos com DM1. Método: Nas bases de dados PsycINFO e PubMed foram pesquisados artigos empíricos de texto completo publicados entre janeiro de 2004 a março de 2019, e que relacionaram variáveis de funcionamento psicológico parental (pai, mãe e/ou cuidadores) e o controle glicêmico, por meio da hemoglobina glicada (HbA1c) de crianças com DM1. Resultados: 24 artigos empíricos foram selecionados. Dez (41,6%) estudos observaram relações significativas entre as variáveis parentais e o controle glicêmico das crianças, sendo a autoeficácia parental no diabetes e a numeracia parental os principais preditores da HbA1c das crianças. Conclusão: Os resultados observados revelaram evidências mistas e ainda inconclusivas. No entanto, ao identificar os efeitos que algumas variáveis parentais exercem no controle glicêmico infantil, intervenções para pais/cuidadores podem ser desenvolvidas e testadas no contexto do DM1 na infância.
Forced Degradation Studies to Assess the Stability of a Janus Kinase Inhibitor Using RPLC Method
Authors: Yilmaz Hulya 
Published: April 2021

In optimization studies, it is important to study the retention behavior of the compounds containing the ionizable functional groups under the intended chromatographic conditions. In this study, the influence of pH and acetonitrile (ACN) composition in the mobile phase on chromatographic behavior of tofacitinib (TOF), a Janus kinase (JAK) inhibitor, was thoroughly investigated. First, the chromatographic conditions were optimized using retention factors and pKa values. Then, the developed method was used for the stability studies under various stress conditions, and for the estimation of TOF concentration in tablets. Finally, the method was verified using the International Conference on Harmonization procedure (ICH-Q2) and was successfully used to separate the TOF degradation products. A linearity range, the limits of detection and quantification were confirmed as 2.0-12.0, 0.416, and 1.260 μg/mL, respectively. Between-day and within-day accuracy (RSD%) were found to be as 0.290 and 0.462 for 4 μg/mL, respectively. The result indicates that the developed method is rather effective to isolate the parent drug from the degradation elements.
Potentialité des données satellitaires Sentinel-2 pour la cartographie de l’impact des feux de végétation en Afrique tropicale : application au Togo
Authors: KONKO Yawo , AFELU Bareremna , KOKOU Kouami 
Published: April 2021

Le réchauffement climatique est un phénomène d’envergure mondiale qui se répercute sur le système climatique. Une des conséquences du réchauffement climatique est l'extension de la période de sécheresse, favorisant ainsi l’augmentation des fréquences du phénomène des feux de végétation. Les feux incontrôlés perturbent l’écologie et la fonctionnalité des écosystèmes, entraînant parfois leur érosion. La présente étude est une contribution pour la gestion des feux de végétation au Togo et porte sur le suivi spatial pour la saison des feux 2018-2019. Elle explore la potentialité des nouvelles données satellitaires Sentinel-2 (S-2) en accès libre dans la gamme de la télédétection optique pour la détection des surfaces brûlées, la cartographie des feux utilitaires et des feux incontrôlés. Elle teste également la performance de la méthode de cartographie des feux de végétation à partir de l’indice NBR (Normalized Burn Ratio) initialement conçue pour les images Landsat et évalue la biomasse végétale brûlée. Les résultats révèlent que les images S-2 présentent du potentiel dans la restitution des surfaces brûlées. La performance de la méthode de l’indice NBR sur les images S-2 est satisfaisante. La cartographie des feux de végétation montre que les feux utilitaires représentent 21,75 % contre 78,25 % pour les feux incontrôlés. L’ensemble des feux de végétation enregistrés a occasionné l’incendie de 5 878 km2 du couvert végétal, soit 10,39 % du territoire national. Le couvert végétal brûlé est composé majoritairement de savanes (33,12 %), de cultures et jachères (24,48 %), de plantations (14,59 %), de forêts claires (14,43 %) et de forêts riveraines (13,02 %). Les résultats obtenus constituent des éléments tangibles pour le suivi, la sensibilisation, l’élaboration des plans d’aménagement, de prévention et de gestion des feux.
Relationship Between Characteristics of Marine Debris and Impact to Coral Reef
Authors: Arindra Putra Muhamad Gilang , Zamani Neviaty Putri , Natih Nyoman Metta , Harahap Syawaludin Alisyahbana 
Published: April 2021

HighlightMarine debris can be as a treat for coral reefBranching coral is the most affected by marine debrisPlastic marine debris commonly found in all research location, especially from fisheries and daily activityAbstractA coral reef is one of the important ecosystems, however, the existence of coral reef is threatened. Several factors can be a threat to the coral reef, such as marine debris. Research about marine debris on coral reefs in Indonesia has not much been done. This research aims to identify marine debris that is found and impacted, to identify the impacts caused, and to identify the life forms most susceptible to being affected. This research was conducted in Kelapa Island, Kelapa Dua Island, and Harapan Island by using the Belt Transect method sized 20 x 4 m2 with four repetitions at each station to determine coral reef life form, and type of marine debris. The data was analyzed by using the Correspondence Analysis (CA) to determine the correlation of marine debris and the affected life forms of coral reefs. The result showed the plastic marine debris was found in all stations. Six life forms were affected by marine debris, and the most susceptible life forms that affected were massive and branching. The most dominant impact category on coral reefs was tissue loss with algal growth (TLAG).
Primer hiperparatiroidizm için cerrahi tedavi sonuçlarının değerlendirilmesi: Tek merkez deneyimi
Authors: ATAŞ Hakan , YUKSEK Yunus , CEYLAN Cengiz , MENEKŞE Ebru , ALTUN ÖZDEMİR Buket , ÇOMÇALI Bülent , TÜTÜNCÜ Tanju , KORUKLUOĞLU Birol 
Published: April 2021

AMAÇ: Primer hiperparatiroidizm (PHPT), dört paratiroid bezinin bir veya daha fazlasından aşırı paratiroid hormonu (PTH) salgılanmasıyla karakterize bir hastalıktır. Anormal paratiroid bezlerinin cerrahi olarak çıkarılması, hastalığın en etkili tedavi yötemidir. Bu çalışma, PHPT nedeniyle ameliyat edilen hastaların klinik ve cerrahi deneyimlerimizi sunmayı amaçlamaktadır.
GEREÇ VE YÖNTEM: Ocak 2014 - Mart 2019 tarihleri arasında hastanemiz meme ve endokrin cerrahisi bölümünde PHPT tanısı ile ameliyat edilen hastaların verileri geriye dönük olarak incelendi.
BULGULAR: Bu çalışmaya medyan yaşı 54 olan toplam 334 hasta (dağılım 16-86) dahil edildi. Bunlardan 165'i (% 81,7) kadın, 37'si (% 18,3) erkekti. Preoperatif lokalizasyon çalışmalarında, en yüksek doğru tespit oranı, anormal paratiroid bezlerinin % 85.7'sini tanımlayan sestamibili tek foton emisyonlu bilgisayarlı tomografi ve ultrasonografi ile elde edildi. Hastaların % 22.16'sında minimal invaziv yöntem, %76,94'ünde bilateral boyun eksplorasyonu tercih edildi. 3 hastada sternotomi gerekti. Patolojik bezlerin ektopik lokalizasyonu 26 (% 7.788) hastada mevcuttu. Eş zamanlı tiroidektomi 124 (% 37.12) hastaya uygulandı. 14 (% 11.29) hastada rastlantısal tiroid maligniteleri teşhis edildi. Persitent ve rekürren hastalık görülme sıklıkları sırasıyla 6.88% ve 4.19% olarak tespit edildi.
SONUÇ: PHPT, multidisipliner bir yaklaşım gerektirir. Cerrahi tedavi, düşük komplikasyon oranları ile% 95'in üzerinde iyileşme sağlayabilir. Anormal bezler için dikkatli lokalizasyon çalışmaları ve eşlik eden tiroid patolojileri için ayrıntılı incelemelerin ameliyat başarısını daha da artıracağına inanıyoruz.
Studi Literatur: Peningkatan Oral Activity dan Hasil Belajar Kognitif melalui Penerapan Model Pembelajaran Search, Solve, Create and Share (SSCS) Materi Sistem Ekskresi pada Manusia
Authors: Widyati Fasaila Nadif , Irawati Hani 
Published: April 2021

Dominansi pendekatan pembelajaran teacher center menyebabkan <em>oral activity</em> siswa dan hasil belajar kognitif siswa rendah pada materi sistem ekskresi. Penerapan model pembelajaran SSCS diharapkan dapat meningkatkan <em>oral activity</em> dan hasil belajar kognitif siswa. Penelitian ini bertujuan untuk mengetahui peningkatan <em>oral activity</em> dan hasil belajar kognitif siswa melalui model pembelajaran SSCS pada materi sistem ekskresi berdasarkan studi literatur. Jenis penelitian ini merupakan penelitian studi literatur. Artikel ilmiah sebagai data penelitian berasal dari jurnal nasional, prosiding dan repository. Validasi artikel dilakukan dengan pertimbangan artikel ilmiah bersifat open access, kualitas metodologi penelitian, kualitas penyajian data dan pembahasan, kecukupan data yang relevan, referensi mutakhir. Teknik pengumpulan data dengan cara koding definisi dan format penyajian data dalam tabel. Teknik analisis data menggunakan analisis deskriptif. Berdasarkan studi literatur menunjukkan bahwa model pembelajaran SSCS dapat meningkatkan <em>oral activity</em> dan hasil belajar kognitif siswa. Hal ini diketahui melalui analisis data artikel ilmiah relevan terdapat pengaruh yang signifikan terhadap peningkatan <em>oral activity</em> dan hasil belajar kognitif. <em>Oral activity</em> siswa terlihat dalam penerapan model pembelajaran SSCS pada tahapan solve dan share. Model pembelajaran SSCS mendukung siswa mengembangkan kemampuan berpikir sehingga perolehan hasil belajar kognitif siswa meningkat. Selain itu, model pembelajaran SSCS dapat diterapkan pada materi sistem ekskresi.
Modified Stoppa Approach: Beyond Acetabular Fractures
Authors: Rizkallah Maroun , Bernardeau Anais , Upex Peter , Moreau Pierre Emmanuel , Abid Hichem , Jouffroy Pomme , Riouallon Guillaume 
Published: April 2021

Cases:
We used the modified Stoppa approach in a 17-year-old man with a retained bullet in his acetabular fossa. The acetabular hole was used to irrigate the hip joint. We also used this approach in a 29-year-old woman with right hip pain and limping to remove an isolated tenosynovial giant cell tumor (“localized pigmented villonodular synovitis”) in the acetabular fossa expanding through the acetabulum.

Discussion:
We believe that this approach should become more familiar because it offers a simple alternative for treating acetabular pathologies mainly involving the acetabular fossa, sparing patients the hazards of capsulotomy, trochanteric osteotomy, dislocation, and traction and fluid pressure in hip arthroscopy.
Distal Clavicle Physeal Separation Mimicking an Acromioclavicular Joint Separation
Authors: Aebischer Andrea S. , Sarai Harminder , Wall Christopher J. 
Published: April 2021

Case:
A 9-year-old boy sustained a right distal clavicle physeal separation with superior and posterior displacement through the periosteum. He was treated surgically with open reduction, Kirschner wire fixation, and periosteal repair and had an excellent outcome.

Conclusion:
Distal clavicle fractures are rare in children, and acromioclavicular joint (ACJ) separations are exceedingly rare. Differentiating between the 2 is often difficult radiographically and clinically. Our case represents a Type IV distal clavicle fracture but could be confused with an ACJ separation. Surgical treatment was successful.
Generative Capacity of Probabilistic Protein Sequence Models
Authors: McGee Francisco , Novinger Quentin , Levy Ronald , Carnevale Vincenzo , Haldane Allan 
Published: April 2021

Abstract
Potts models and variational autoencoders (VAEs) have recently gained popularity as generative protein sequence models (GPSMs) to explore fitness landscapes and predict the effect of mutations. Despite encouraging results, quantitative characterization and comparison of GPSM-generated probability distributions is still lacking. It is currently unclear whether GPSMs can faithfully reproduce the complex multi-residue mutation patterns observed in natural sequences arising due to epistasis. We develop a set of sequence statistics to comparatively assess the accuracy, or “generative capacity”, of three GPSMs: a pairwise Potts Hamiltonian, a vanilla VAE, and a site-independent model, using natural and synthetic datasets. We show that the generative capacity of the Potts Hamiltonian model is the largest; the higher order mutational statistics generated by the model agree with those observed for natural sequences. In contrast, we show that the vanilla VAE’s generative capacity lies between the pairwise Potts and site-independent models. Importantly, our work measures GPSM generative capacity in terms of higher-order sequence covariation and provides a new framework for evaluating and interpreting GPSM accuracy that emphasizes the role of epistasis.
Multi-objective Water Resources Optimum Allocation Scheme Based on Improved Standard Cuckoo Searching Algorithm (ISCSA)
Authors: Zhou Ke 
Published: April 2021

Abstract
The standard cuckoo searching algorithm(SCSA)is a population intelligent optimization algorithm, which is also a new heuristic searching algorithm. The advantages of SCSA (such as convenient operation, heuristic searching, etc.) make it easy to find the optimal solution and maintain wider searching range. However, SCSA also has some drawbacks, such as long searching time, easy to fall into local optimum. In order to solve the problems existed in SCSA, in this paper, the improved standard cuckoo searching algorithm (ISCSA) was studied, which includes chaotic initialization and Gaussian disturbed algorithm. As a case study, taking economic, social and ecological benefits as the objective function, the multi-objective water resources optimal allocation models were constructed in Xianxiang Region, China. The ISCSA was applied to solve the water allocation models and the multi-objective optimal water supply scheme for Xinxiang region was obtained. The water resources optimal allocation schemes in the planning level year (2025) for 12 water supply sub-regions were predicted. The desirable eco-environment and benefits were achieved using the studied methods. The results show that the ISCSA has obvious advantages in the solution of water resources optimal allocation and planning.
Central corneal thickness measurements in phakic, pseudophakic, and aphakic children with ultrasound pachymetry and different non-contact devices
Authors: Farvardin Majid , Shamsi Anis , Norouzpour Amir , Jalalpour Mohammad-Hasan 
Published: April 2021

Abstract
Aims: Evidence for choosing a satisfactory device for central corneal thickness (CCT) measurement in children particularly pseudophakic and aphakic ones is insufficient. The aim of this study is to compare four differently-measured CCTs obtained using ultrasound pachymetry (UP), Pentacam, partial coherence interferometry (PCI), and specular microscopy (SM) in phakic, pseudophakic, and aphakic children and assess the agreement between the six pairs of the methods. Methods: Children with history of cataract surgery at age six or younger and phakic children were recruited into this study. CCT was measured using UP (Optikon 2000, Rome, Italy), Pentacam (Oculus Inc, Wetzlar, Germany), PCI (IOLMaster 700, Carl Zeiss Meditec AG, Jena, Germany), and SM (Topcon SP-3000P; Topcon Corporation, Japan).Results: One-hundred two eyes (53 phakic, 29 pseudophakic, and 20 aphakic eyes) were included. The mean ages (±SD) of phakic, pseudophakic, and aphakic cases were 9.75 (±3.3), 9.9 (±2.3), and 8.2 (±2.8) years respectively. The mean CCTs (±SE) for phakic children using Pentacam, PCI, UP, and SM were 549.7 (±5.0), 546.5 (±4.5), 565.9 (±5.5), and 506.2 (±4.4) mm respectively, for pseudophakic cases were 570.1 (±6.4), 565.0 (±6.1), 571.9 (±6.3), and 524.3 (±6.3) mm respectively, and for aphakic participants were 635.3 (±14.2), 635.4 (±14.5), 649.0 (±13.5), and 589.1 (±13.3) mm respectively. Conclusion: Compared to Pentacam and PCI, SM underestimated CCT particularly in phakic and pseudophakic children, whereas UP slightly overestimated CCT especially in phakic and aphakic children. Furthermore, Pentacam and PCI had the closest agreement. By contrast, SM had the poorest agreement with the other three methods.