bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enabling the Voices of Marginalized Groups of People in Theoretical Business Ethics Research
Authors: Alm Kristian , Guttormsen David S. A. 
Published: October 2021

AbstractThe paper addresses an understudied but highly relevant group of people within corporate organizations and society in general—the marginalized—as well as their narration, and criticism, of personal lived experiences of marginalization in business. They are conventionally perceived to lack traditional forms of power such as public influence, formal authority, education, money, and political positions; however, they still possess the resources to impact their situations, their circumstances, and the structures that determine their situations. Business ethics researchers seldom consider marginalized people’s voices and experiences as resources to understand their lives, as demonstrated through a review of 7500 articles published in the Journal of Business Ethics and Business Ethics Quarterly (2000–2019). Only 78 studies included aspects of marginalized groups. 69 of those studies discussed the topic of marginalized groups of people, but without integrating their explicit voices into the text. Only 9 of the 78 articles featured marginalized people’s explicit voices about their marginalization experiences incorporated into the text as a source for exploration. None of the identified studies discussed the potential for theorizing based on such voices. This paper contributes to business ethics theory by developing four theoretical possibilities vis-à-vis the critical voices of marginalized people’s experiences in business: (a) marginalized theory on critical agency and freedom of speech; (b) the gatekeeping role of academia; (c) primary sources; and (d) a participative perspective. Discussing the theoretical potential of quoting the above voices can enrich business ethics research in terms of the theoretical understanding of marginalized groups in business.
Subclinical leaflet thrombosis after transcatheter aortic valve implantation: no association with left ventricular reverse remodeling at 1-year follow-up
Authors: Kuneman Jurrien H. , Singh Gurpreet K. , Hansson Nicolaj C. , Fusini Laura , Poulsen Steen H. , Fortuni Federico , Vollema E. Mara , Pedersen Anders L. D. , Annoni Andrea D. , Nørgaard Bjarne L. , Pontone Gianluca , Ajmone Marsan Nina , Delgado Victoria , Bax Jeroen J. , Knuuti Juhani 
Published: October 2021

AbstractHypo-attenuated leaflet thickening (HALT) of transcatheter aortic valves is detected on multidetector computed tomography (MDCT) and reflects leaflet thrombosis. Whether HALT affects left ventricular (LV) reverse remodeling, a favorable effect of LV afterload reduction after transcatheter aortic valve implantation (TAVI) is unknown. The aim of this study was to examine the association of HALT after TAVI with LV reverse remodeling. In this multicenter case–control study, patients with HALT on MDCT were identified, and patients without HALT were propensity matched for valve type and size, LV ejection fraction (LVEF), sex, age and time of scan. LV dimensions and function were assessed by transthoracic echocardiography before and 12 months after TAVI. Clinical outcomes (stroke or transient ischemic attack, heart failure hospitalization, new-onset atrial fibrillation, all-cause mortality) were recorded. 106 patients (age 81 ± 7 years, 55% male) with MDCT performed 37 days [IQR 32–52] after TAVI were analyzed (53 patients with HALT and 53 matched controls). Before TAVI, all echocardiographic parameters were similar between the groups. At 12 months follow-up, patients with and without HALT showed a significant reduction in LV end-diastolic volume, LV end-systolic volume and LV mass index (from 125 ± 37 to 105 ± 46 g/m2, p = 0.001 and from 127 ± 35 to 101 ± 27 g/m2, p < 0.001, respectively, p for interaction = 0.48). Moreover, LVEF improved significantly in both groups. In addition, clinical outcomes were not statistically different. Improvement in LVEF and LV reverse remodeling at 12 months after TAVI were not limited by HALT.
Sodium-glucose cotransporter 2 inhibitors and heart failure: the best timing for the right patient
Authors: Severino Paolo , D’Amato Andrea , Prosperi Silvia , Costi Bettina , Angotti Danilo , Birtolo Lucia Ilaria , Chimenti Cristina , Lavalle Carlo , Maestrini Viviana , Mancone Massimo , Fedele Francesco 
Published: October 2021

AbstractSodium-glucose cotransporter 2 inhibitors (SGLT2i), initially born as anti-diabetic drugs, have shown many beneficial effects on the cardiovascular system, in particular against heart failure (HF). HF is a complex and multifaceted disease that requires a comprehensive approach. It should not be considered as a simplistic cardiac disease, but a systemic disease that leads to multisystemic organ failure and death. Exploiting their pleiotropic effects, SGLT2i are a very valid tool for HF treatment. Beyond the indication to reduce HF hospitalization and death risk, in patients with diabetes mellitus at high cardiovascular risk or with established cardiovascular event, SGLT2i administration reported beneficial effects regarding the wide spectrum of HF manifestations and stages, independently by diabetes mellitus presence. Recent evidence focuses on HF rehospitalization, cardiac and all-cause death reduction, as well as symptoms and quality of life improvement, in patients with chronic HF or with a recent HF decompensation episode. Given the recent finding about the SGLT2i usefulness in HF patients, further studies are needed to define the best administration timing to maximize the SGLT2i-derived beneficial effects.
Device design and optimization of CNTFETs for high-frequency applications
Authors: Peng Boli , Annamalai Manojkumar , Mothes Sven , Schröter Michael 
Published: October 2021

AbstractCarbon nanotube (CNT) field-effect transistors (FETs) have recently reached high-frequency (HF) performance similar to that of silicon RF-CMOS at the same gate length despite a tube density and current per tube that are far from the physical limits and suboptimal device architecture. This work reports on an investigation of the optimal device design for practical HF applications in terms of cut-off frequencies, power gain, and linearity. Different fundamental designs in the gate contact arrangement are considered based on a 3D device simulation of both CNTs and contacts. First, unit cells with a single CNT and minimal contact sizes are compared. The resulting simulation data are then extended toward a structure with two gate fingers and realistic contact sizes. Corresponding parasitic capacitances, as well as series and contact resistances, have been included for obtaining realistic characteristics and figures of merit that can be used for comparison with corresponding silicon RF MOSFETs. Finally, a sensitivity analysis of the device architecture with the highest performance is performed in order to find the optimal device design space.
The Readiness for Return to Work Scale; Does it Help in Evaluation of Return to Work?
Authors: Aasdahl Lene , Fimland Marius Steiro , Røe Cecilie 
Published: October 2021

AbstractPurpose The Readiness for Return to Work (RRTW) scale is used to evaluate workers’ readiness to resume work after sick leave. Previous research has questioned the RRTW scale’s constructs and stages. The aim of this study was to assess the unidimensionality of the RRTW scale and its six subscales by evaluating its fit to the Rasch model, and furthermore to assess if Rasch-based scaling would improve its predictive value, compared with the conventional use of the scale. Methods A prospective cohort study with 12 months of follow-up. Individuals (n = 397) sick-listed due to musculoskeletal, unspecified, or common mental health disorders undergoing rehabilitation were included: 191 were full-time sick-listed (not working), and 206 were part-time sick-listed (working). A Rasch analysis was applied to evaluate the measurement properties of the RRTW scale in the working and not working participants at baseline. Linear and logistic regressions were used to assess how well Rasch-based scaling predicted future work participation during the 12 months of follow-up. Results The RRTW subscales had too few items to represent underlying dimensions properly, and the items fitted poorly within the subscales. A constructed variable based on the items that fit together for not working individuals poorly predicted future work participation. The individuals’ scores across stages were disordered, indicating a lack of ordered stages. Conclusions This study reveals poor measurement properties of the Norwegian version of the RRTW scale in individuals with musculoskeletal and common mental disorders, with neither the subscales nor the stages closely associated with return to work.
What is a plant nutrient? Changing definitions to advance science and innovation in plant nutrition
Authors: Brown Patrick H. , Zhao Fang-Jie , Dobermann Achim 
Published: October 2021

AbstractCurrent definitions of essential or beneficial elements for plant growth rely on narrowly defined criteria that do not fully represent a new vision for plant nutrition and compromise fertilizer regulation and practice. A new definition of what is a plant nutrient that is founded in science and relevant in practice has the potential to revitalize innovation and discovery. A proposed new definition might read: A mineral plant nutrient is an element which is essential or beneficial for plant growth and development or for the quality attributes of the plant or harvested product, of a given plant species, grown in its natural or cultivated environment. A plant nutrient may be considered essential if the life cycle of a diversity of plant species cannot be completed in the absence of the element. A plant nutrient may be considered beneficial if it does not meet the criteria of essentiality, but can be shown to benefit plant growth and development or the quality attributes of a plant or its harvested product. It includes elements currently identified as essential, elements for which a clear plant metabolic function has been identified, as well as elements that have demonstrated clear benefits to plant productivity, crop quality, resource use efficiency, stress tolerance or pest and disease resistance. We propose an open scientific debate to refine and implement this updated definition of plant nutrients. Other outcomes of this debate could be a more precise definition of the experimental evidence required to classify an element as a plant nutrient, and an independent scientific body to regularly review the list of essential and beneficial nutrients. The debate could also attempt to refine the definition of plant nutrients to better align with nutrients deemed essential for animal and human nutrition, thus following a more holistic ’one nutrition‘ concept.
A novel survey of raptor collections in Europe and their potential to provide samples for pan-European contaminant monitoring
Authors: Ramello Gloria , Duke Guy , Dekker Rene W. R. J. , van der Mije Steven , Movalli Paola 
Published: October 2021

AbstractThis paper provides a novel survey of current collections of frozen raptor carcasses and tissue samples in natural history museums (NHMs), environmental specimen banks (ESBs) and other research collections (ORCs e.g. at universities and research institutes) across Europe and assesses the extent to which collections might support pan-European raptor biomonitoring through the provision of samples for contaminant analyses. The paper is based on questionnaire responses received in late 2018 and early 2019 from 116 institutions. Issues covered include the number of raptor carcasses and diversity of raptor species arriving annually at collections, the number of carcasses stored in freezers, the extent to which collections retain frozen tissue samples, what records are kept of carcasses and tissue samples, constraints to expanding collections of frozen carcasses and tissues and the extent to which collections currently engage in ecotoxicological research and monitoring. Our findings show that collections in Europe receive well over 5000 raptor carcasses per annum, and that NHMs are the key recipients of raptor carcasses for most countries. Collections in Europe probably hold well over 10,000 raptor carcasses in their freezers, offering a substantial resource of frozen raptor carcasses and tissues from recent years. Moreover, these carcasses include good specimen numbers for species that have been prioritized for pan-European contaminant monitoring. Collections are becoming digitized aiding access to samples. However, freezer capacity is a key constraint to retention of carcasses, and contaminant biomonitoring is novel for most NHMs. Our findings on the repository and availability of frozen raptor carcasses and tissues held by collections in Europe can enable greater use of these specimens for pan-European contaminant monitoring in support of better chemicals management. We highlight opportunities to further optimize raptor collections for pan-European contaminant monitoring.
Transplanting Hybrid Potato Seedlings at Increased Densities Enhances Tuber Yield and Shifts Tuber-Size Distributions
Authors: van Dijk Luuk C. M. , de Vries Michiel E. , Lommen Willemien J. M. , Struik Paul C. 
Published: October 2021

AbstractTo contribute to the development of a novel cropping system for potato grown from greenhouse-derived seedlings from hybrid true potato seeds, planting density trials were carried out under normal Dutch agronomic conditions. For two consecutive years, 5-week-old seedlings of two experimental genotypes were transplanted into farmers’ potato production fields at two contrasting locations: a flat-bed system on sandy soil and a traditional ridge system on clay soil. Planting densities were 6.25, 12.5, 25, 50, 100 and 200 plants/m2 in the flat-bed system, and 3.125, 4.688, 6.25, 12.5, 25 and 50 plants/m2 in the ridge system. In general, increasing planting density of hybrid seedlings per area decreased tuber fresh weight per plant and reduced the number of tubers per plant. On a per hectare basis, an increased planting density resulted in increased total tuber yield and number of tubers up to very high densities, but finally both parameters levelled off. Highest total tuber yields harvested were 107 and 45 Mg/ha for the flat-bed and ridge system, respectively. On flat-beds, the optimal planting density for total yield was 50 plants/m2. On ridges, planting density interacted with year and genotype, resulting in an optimum planting density of 25 plants/m2 to reach the maximum total yield. Obtained yields in the commercial size classes Baby Baker (20 < size class ≤ 35 mm) and Seed Tubers (28 < size class ≤ 50 mm) were in general very high on the flat-beds, with a maximum Seed Tuber yield of 64 Mg/ha at 50 plants/m2. The current study showed that transplanted hybrid seedlings are feasible alternatives for seed-tuber-grown systems for certain potato outlets.
Sexual health-related care needs among young adult cancer patients and survivors: a systematic literature review
Authors: Lehmann Vicky , Laan Ellen T. M. , den Oudsten Brenda L. 
Published: October 2021

Abstract
Purpose
Young adult cancer patients and survivors have age-specific care needs, but care needs related to sexual health are poorly understood. A systematic literature review was conducted to examine sexual health-related care needs among patients/survivors diagnosed with cancer during young adulthood (age: 18–39 years). The prevalence and types needs were assessed along with associated patient factors.

Methods
Four major databases were screened to identify relevant studies, which were also assessed for risk of bias; all following PRISMA guidelines.

Results
Identified studies (N = 35) often assessed sexual health-related care needs by whether participants experienced a generic need for support from providers. The prevalence of such needs ranged between 8 and 61.7% and was higher in female survivors and those with more health impairments. The type of diagnosis could also play a role in these varying prevalence rates, but was not systematically tested in included studies. Types of sexual health-related care needs were clustered into practical/emotional support needs (e.g., coping with physical side effects), information needs (e.g., more details), and communication needs (e.g., providers should initiate conversations, validate concerns, be empathetic/open). Needs should be addressed in-person and/or online.

Conclusions
The extent of needs related to sexual health varies among young adult patients and survivors, but types of needs center around improving provision of support and information by providers.

Implications for Cancer Survivors
Sexual health should routinely be addressed alongside other potential effects of cancer treatment to allow for constructive conversations between patients and providers. Referrals to (online) resources or specialists should be tailored to individual preferences.
Fixed point theorems in preordered sets
Authors: Górnicki Jarosław 
Published: October 2021

AbstractRan and Reurings (Proc Am Math Soc 132(5):1435–1443, 2003) extended the Banach contraction principle to the setting of partially ordered metric spaces and recently Proinov (J Fixed Point Theory Appl 22:21, 2020) extended and unified many earlier fixed point theorems. In this paper we will present analogous results for the significantly wider class of mappings on preordered metric spaces. We give non-trivial examples of Kannan-type mappings.
Ambarzumian-type Problems for Discrete Schrödinger Operators
Authors: Hatinoğlu Burak , Eakins Jerik , Frendreiss William , Lamb Lucille , Manage Sithija , Puente Alejandra 
Published: October 2021

AbstractWe discuss the problem of unique determination of the finite free discrete Schrödinger operator from its spectrum, also known as the Ambarzumian problem, with various boundary conditions, namely any real constant boundary condition at zero and Floquet boundary conditions of any angle. Then we prove the following Ambarzumian-type mixed inverse spectral problem: diagonal entries except the first and second ones and a set of two consecutive eigenvalues uniquely determine the finite free discrete Schrödinger operator.
Identification of cell cycle as the critical pathway modulated by exosome-derived microRNAs in gallbladder carcinoma
Authors: Su Li , Zhang Jicheng , Zhang Xinglong , Zheng Lei , Zhu Zhifa 
Published: October 2021

AbstractGallbladder cancer (GBC), the most common malignancy in the biliary tract, is highly lethal malignant due to seldomly specific symptoms in the early stage of GBC. This study aimed to identify exosome-derived miRNAs mediated competing endogenous RNAs (ceRNA) participant in GBC tumorigenesis. A total of 159 differentially expressed miRNAs (DEMs) was identified as exosome-derived miRNAs, contains 34 upregulated exo-DEMs and 125 downregulated exo-DEMs based on the expression profiles in GBC clinical samples downloaded from the Gene Expression Omnibus database with the R package. Among them, 2 up-regulated exo-DEMs, hsa-miR-125a-3p and hsa-miR-4647, and 5 down-regulated exo-DEMs, including hsa-miR-29c-5p, hsa-miR-145a-5p, hsa-miR-192-5p, hsa-miR-194-5p, and hsa-miR-338-3p, were associated with the survival of GBC patients. Results of the gene set enrichment analysis showed that the cell cycle-related pathways were activated in GBC tumor tissues, mainly including cell cycle, M phase, and cell cycle checkpoints. Furthermore, the dysregulated ceRNA network was constructed based on the lncRNA-miRNA-mRNA interactions using miRDB, TargetScan, miRTarBase, miRcode, and starBase v2.0., consisting of 27 lncRNAs, 6 prognostic exo-DEMs, and 176 mRNAs. Together with prognostic exo-DEMs, the STEAP3-AS1/hsa-miR-192-5p/MAD2L1 axis was identified, suggesting lncRNA STEAP3-AS1, might as a sponge of exosome-derived hsa-miR-192-5p, modulates cell cycle progression via affecting MAD2L1 expression in GBC tumorigenesis. In addition, the biological functions of genes in the ceRNA network were also annotated by Gene Ontology and Kyoto Encyclopedia of Genes and Genomes. Our study promotes exploration of the molecular mechanisms associated with tumorigenesis and provide potential targets for GBC diagnosis and treatment.
It’s all about control: Sense of control mediates the relationship between physical activity and mental health during the COVID-19 pandemic in Germany
Authors: Precht Lena-Marie , Margraf Jürgen , Stirnberg Jan , Brailovskaia Julia 
Published: October 2021

AbstractCOVID-19-related burden has a significant impact on mental health and has led to an increase of depression, anxiety, and stress symptoms. Physical activity has been suggested to mitigate the negative effects of the pandemic and to foster mental health. The present study aimed to investigate, whether sense of control might mediate the supposed beneficial effects of physical activity on positive (PMH) and negative mental health (NMH) in unpredictable extraordinary situations. Data were assessed in a sample of 568 students (Mage = 19.90, SDage = 4.52) from Germany via an online survey in fall 2020. Mediation analyses revealed that sense of control mediated the relation between physical activity and PMH as well as depression, anxiety, and stress symptoms, respectively. The findings indicate that physical activity may be a promising strategy for fostering sense of control and thus mental health. Due to its practical implications and practicability, engagement in physical activity could be an effective way to reduce the NMH consequences of the current COVID-19 situation, and therefore should be addressed in actions for long-term prevention and intervention.
Identification hub genes of consensus molecular subtype correlation with immune infiltration and predict prognosis in gastric cancer
Authors: Yu Xin , Yu Bin , Fang Weidan , Xiong Jianping , Ma Mei 
Published: October 2021

AbstractGastric cancer (GC) has a great fatality rate, meanwhile, there is still a lack of available biomarkers for prognosis. The goal of the research was to discover key and novel potential biomarkers for GC. We screened for the expression of significantly altered genes based on survival rates from two consensus molecular subtypes (CMS) of GC. Subsequently, functional enrichment analysis showed these genes involved in many cancers. And we picked 6 hub genes that could both secreted in the tumor microenvironment and expression enhanced in immune cells. Then, Kaplan Meier survival and expression detected in the tumor pathological stage were utilized to clarify the prognostic of these 6 hub genes. The results indicated that OGN, CHRDL2, C2orf40, THBS4, CHRDL1, and ANGPTL1, respectively, were significantly associated with poor OS in GC patients. And their expression increased with cancer advanced. Moreover, immune infiltration analysis displayed that those hub genes expression positively with M2 macrophage, CD8+ T Cell, most immune inhibitors, and majority immunostimulators. In summary, our results suggested that OGN, CHRDL2, C2orf40, THBS4, CHRDL1, and ANGPTL1 were all potential biomarkers for GC prognosis and might also be potential therapeutic targets for GC.