bluuebunny/crossref_metadata_2025_split huggingface dataset:
New Insights on Sodium Oleate Adsorption on Quartz for Iron Direct Flotation under Weak-Acidic Condition
Authors: Hou Ying , Sobhy Ahmed 
Published: May 2021

Abstract
To study the sodium oleate (NaOL) adsorption on quartz and its effect on flotation under weak-acidic conditions, the adsorption characteristics of NaOL on the surface of quartz were determined at pH = 6.5 by Fourier transform infrared spectroscopy (FTIR). The solution chemical calculation results show that NaOL exists as oleic acid (HOL) under weakly acidic conditions. The existence form and charge distribution of quartz and HOL were analyzed by Molecular Dynamics Simulation (MDS) using Materials Studio (MS) software, and the results showed that HOL is prone to the (101) and (100) surfaces of quartz under weak-acidic conditions by hydrogen bonding. The flotation verification test with NaOL as a collector was also performed under weak-acidic conditions. The flotation test led to a partial flotation of quartz into the froth products, reducing the grade of hematite direct flotation concentrate, which is consistent with industrial production.
Aile Katılım Çalışmalarına Yönelik Okul Öncesi Öğretmenlerinin Bilişsel Haritaları
Authors: URAL Ozana , GÜNŞEN Gülşah 
Published: May 2021

Araştırma kapsamında okul öncesi öğretmenlerinin aile
katılım çalışmalarına yönelik tutumlarının, gerçekleştirmiş oldukları aile
katılım çalışmalarının özelliğinin (içerik ve yer verme sıklığı) belirlenmesi
amaçlanmıştır. Karma araştırma yöntemi kullanılarak yapılan bu araştırmanın
katılımcılarını 2016-2017 eğitim öğretim yılında Edirne ilinde MEB’e bağlı
sosyo-ekonomik ve sosyo-kültürel açıdan farklı bölgelerde bulunan bağımsız ana okullarında görev yapmakta olan 35 okul öncesi öğretmeni oluşturmaktadır. Araştırmada
nicel veri toplama aracı olarak Bayraktar, Güven ve Temel (2016) tarafından
geliştirilen Öğretmenler İçin Aile Katılım Çalışmalarına Yönelik Tutum Ölçeği,
nitel veri toplama aracı olarak da araştırmacılar tarafından geliştirilen
görüşme formu kullanılmıştır. Çalışmanın nicel verileri SPSS 24 programı
aracılığıyla tek yönlü varyans analizi ve ilişkisiz (bağımsız) örneklemler
t-testi ile analiz edilmiştir. Demografik Bilgiler anketinden elde edilen
demografik özellikler yüzdeler halinde sunulmuştur. Nitel veri analizi için
içerik analizinden yararlanılmıştır. Bu bulgular kullanılarak aile katılım
çalışmalarının karmaşık yapısını daha iyi anlamak için görsel bir sunum
sağlayan bilişsel haritalardan yararlanılmıştır. Araştırmanın nicel verilerinden elde edilen sonuçlara göre okul öncesi
öğretmenlerinin aile katılım çalışmalarına yönelik tutumlarında cinsiyet, yaş,
meslek yılı, mezun olunan okul türü, aile katılım çalışmalarına yönelik
herhangi bir eğitim alıp almama durumu değişkenlerinin etkili olmadığı ortaya
çıkmıştır. Araştırmanın nitel
sonuçlarına göre ise aile katılım çalışmalarının öneminin farkında oldukları
ancak uygulamalarında yeterli düzeyde yer vermedikleri görülmektedir.
Application of Reinforcement Learning to Optimize Business Processes in the Bank
Authors: Bugaenko Andrey A. 
Published: May 2021

This article describes the application of reinforcement learning (q-learning, genetic algorithm, cross-entropy) to define the optimal structure of business processes in the bank. It describes the principle of creation of the environment, loss, and reward. Setting of hyperparameters for each method is considered in depth. Besides, it offers the variant of calculation of the maximum potential for saving, which can be arrived at through the business process optimization.
Javanese People's Acceptance of Arabic Calligraphy as Home Decoration
Authors: Et al. Retno Purnama Irawati 
Published: May 2021

The interweaving of Arabic calligraphy letters is a combination of artistic art. Arabic calligraphy is giving rise to aspects of visual beauty that can be enjoyed and created a sense of joy. It can encourage people to get closer to Allah, love for goodness, nobility, and so on. Arabic calligraphy is infused into the hearts of those who see, by the meaning of the text. Apart from being a form of reception for one of the verses in the Koran, namely in the verse al-Kursī, calligraphy has developed in various forms and includes various functions and fields that are indirectly connected with the text of the Quran. Starting from the context of the Koran alone, and the spiritual substance of the Koran that continues to live in all aspects of traditional Islamic calligraphy. Calligraphy is also the choice of Muslims in Central Java to decorate the walls of their homes. The choice of calligraphy to decorate the walls of the house is based on various reasons, ranging from aesthetic, religious, to magical reasons. This research was conducted to conduct a more in-depth analysis of the Central Javanese people's reception of Arabic calligraphy as a home decoration and to analyze the reasons for choosing Arabic calligraphy as a home wall decoration for the Muslim community of Central Java. This research is qualitative research with a phenomenological research design. The data collection technique is done using documentation techniques, interviews, and distributing questionnaires. The questionnaire was created using a combination open and closed question model for all groups of respondents. Data analysis in this study used statistical calculations on respondents' answers to the questionnaire, which were analyzed qualitatively. The research subjects were the Muslim community in Central Java, totaling 164 adults. When viewed from the gender of the respondents, 91 people (or 55% of respondents) were male, and 73 people (or 45% of respondents) were female. Calligraphy is a medium for conveying religious messages through language. The language chosen is a significant or straightforward language that is easy to understand or understand in sentences. The writing style displays beautiful shapes so that the type of style that is elastic or flexible and easy to create is chosen to make a beautiful impression, namely the tsutust and naskhiy types. The artistic expression that most strongly displays the substance of calligraphy is the traditional expression that has been chosen as an artistic expression. Figural and expressionist forms of expression were chosen because of their role in providing new nuances of free calligraphic expression
Conceptualization Appropriate Application for Emergency Room Cases for the Unconscious Patients
Authors: Mohammed Alduhaiem, Terkee Alshayae Evan Asfoura, 
Published: May 2021

Applying the new technologies in the health field is growing more and more because of the important effects on the human life. This paper will provide the conceptual model for cloud based application (called Emergency Room (ER) App which support the doctors to improve the diagnostic procedures which will solve an important medical issue at the emergency rooms in case of " an unconscious person". The proposed application will allow storing the sensitive medical information for any person in cloud with high consideration of the privacy aspects. The doctors in the emergency will be able to know all the needed information about the health aspects of the patients directly from the cloud which will be helpful to decide which kind of medicine can be used for recovering the health without any dangerous side effects on those patients.
The result will present two concepts the first one will provide the overview about the health records that should be stored in the cloud and the second provide the workflow which explain how the interaction go among of the actors during the application use.
Analysis of the complete mitochondrial genome sequence of the resurrection plant Haberlea rhodopensis
Authors: Baev Vesselin , Ivanova Zdravka , Yahubyan Galina , Toneva Valentina , Apostolova Elena , Minkov Georgi , Minkov Ivan 
Published: May 2021

Haberlea rhodopensis is a paleolithic tertiary relict species that belongs to the unique group of resurrection plants sharing remarkable tolerance to desiccation. When exposed to severe drought stress, this species shows an ability to maintain structural integrity of its deactivated photosynthetic apparatus, which easily reactivates upon rehydration. In addition to its homoiochlorophyllous nature, the resurrection capability of H. rhodopensis is of particular importance to the global climate change mitigation. In this study, we sequenced, assembled, and analyzed the mitochondrial (mt) genome of H. rhodopensis for the first time. The master circle has a typical circular structure of 484 138 bp in length with a 44.1% GC content in total. The mt genome of H. rhodopensis contains 59 genes in total, including 35 protein-coding, 21 tRNAs, and 3 rRNAs genes. 7 tandem repeats and 85 simple sequence repeats (SSRs) are distributed throughout the mt genome. The alignment of 20 plant mt genomes confirms the phylogenetic position of H. rhodopensis in the Lamiales order. Our comprehensive analysis of the complete mt genome of H. rhodopensis is a significant addition to the limited database of organelle genomes of resurrection species. Comparative and phylogenetic analysis provides valuable information for a better understanding of mitochondrial molecular evolution in plants.
Outcomes Following Severe Distal Tibial, Ankle, and/or Mid/Hindfoot Trauma
Authors:   Major Extremity Trauma Research Consortium (METRC)
Published: May 2021

Background:
Selecting the best treatment for patients with severe terminal lower-limb injury remains a challenge. For some injuries, amputation may result in better outcomes than limb salvage. This study compared the outcomes of patients who underwent limb salvage with those that would have been achieved had they undergone amputation.

Methods:
This multicenter prospective observational study included patients 18 to 60 years of age in whom a Type-III pilon or IIIB or C ankle fracture, a Type-III talar or calcaneal fracture, or an open or closed blast/crush foot injury had been treated with limb salvage (n = 488) or amputation (n = 151) and followed for 18 months. The primary outcome was the Short Musculoskeletal Function Assessment (SMFA). Causal effect estimates of the improvement that amputation would have provided if it had been performed instead of limb salvage were calculated for the SMFA score, physical performance, pain, participation in vigorous activities, and return to work.

Results:
The patients who underwent limb salvage would have had small differences in most outcomes had they undergone amputation. The most notable difference was an improvement in the SMFA mobility score of 7 points (95% confidence interval [CI] = 2.0 to 10.7). Improvements were largest for pilon/ankle fractures and complex injury patterns.

Conclusions:
Amputation should be considered a treatment option rather than a last resort for the most complex terminal lower-limb injuries.

Level of Evidence:
Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.
Occurrence of antimicrobial persistence in Streptococcus pyogenes
Authors: Martini Caroline L. , Coronado Amada Z. , Melo Maria Celeste N. , Gobbi Clarice N. , Lopez Úrsula S. , Mattos Marcos C. , Amorim Thais T. , Botelho Ana Maria N. , Vasconcelos Ana Teresa R. , Almeida Luiz Gonzaga , Planet Paul , Zingali Russolina B. , Figueiredo Agnes Marie S. , Ferreira-Carvalho Bernadete T. 
Published: May 2021

Abstract
Streptococcus pyogenes (group A Streptococcus-GAS) is an important pathogen for humans. GAS has been associated with severe and invasive diseases. Despite the fact that these bacteria remain universally susceptible to penicillin, therapeutic failures have been reported in some GAS infections. Many hypotheses have been proposed to explain these antibiotic-unresponsive infections, however none of them have fully elucidated this phenomenon. In this study, we show that GAS strains have the ability to form antimicrobial-persistent cells when growing on abiotic surfaces in a biofilm-like environment. Our data suggest that efflux activity was possibly involved in this phenomenon. In fact, gene expression assays by real-time qRT-PCR showed upregulation of some genes associated with efflux pumps in persistent cells arising in the presence of penicillin. Phenotypic reversion assay and whole-genome sequence analysis indicated that this event was due to non-inherited resistance mechanisms. The small persistent colonies showed downregulation of genes associated with protein biosynthesis and cell growth, as demonstrated by gene expression assays. Moreover, the proteomic analysis showed that susceptible cells express higher levels of ribosome proteins. It is conceivable to suppose that the generation of persistent cells by S. pyogenes might a mechanism of antimicrobial refractory during the course of real GAS invasive infections, which has been overlooked. Accordingly, the phenomenon described here might shed some light on the origin of therapeutic failures in S. pyogenes infections. Multifactorial mechanisms involving efflux pump activity, protein synthesis inhibition and cell-growth impairment seem to play roles in generation of GAS-persistent cells.
Assessment of Knowledge, Attitude and Practice of Mothers/caregivers on Infant and Young Child Feeding in Assosa Woreda, Assosa Zone, Benshangul Gumuz Region, Western Ethiopia: A Cross Sectional Study
Authors: Assefa Dawit Getachew , Woldesenbet Tigist Tekle , Molla Wondwosen , Zeleke Eden Dagnachew 
Published: May 2021

Abstract
Background Through the health extension package Ethiopia had practiced infant and young child feeding. However, infant and young child feeding (IYCF) practice has been poor. Hence, in this study, the knowledge, attitude, and practice of the mothers/caregivers on infant and young child feeding were assessed.Methods A cross-sectional study was carried out among 486 mothers/caregivers from Assosa Districts in Assosa Zone of Benshangul Gumuz Region, Western Ethiopia. A semi-structured interviewer-administered questionnaire was used. To isolate independent predictors for good knowledge, good practice, and favorable attitude of the mothers/caregivers related to child feeding, multivariable logistic regression analyses were performed. Results Out of 486 study participants, 456(93.8%) of mothers had good knowledge, 432(88.9%) had a positive attitude, and 380 (78.2%) mothers had good practice of IYCF practice recommendations. Furthermore, age of mothers, educational status of the mother, place of delivery, father’s educational status, father’s involvement & support, previous knowledge about IYCF, discussion with their husband about IYCF, and ANC follows up were significantly associated with mother’s knowledge on IYCF recommendation.Conclusions Overall mothers had good knowledge and a positive attitude about IYCF practices. To support IYCF practices, behavior change communications intervention strategies should be introduced in mothers to bridge the gap between knowledge and practices.
Carbon isotopic composition of Frutexites in subseafloor ultramafic rocks
Authors: Neubeck Anna , Ivarsson Magnus , Broman Curt , Zaloumis Jonathan , Bach Wolfgang , Whitehouse Martin 
Published: May 2021

Abstract
Micrometer sized stromatolitic structures called Frutexites are features observed in samples from the deep subsurface, and hot-spring environments. These structures are comprised of fine laminations, columnar morphology, and commonly consist of iron oxides, manganese oxides, and/or carbonates. Although a biological origin is commonly invoked, few reports have shown direct evidence of their association with microbial activity. Here, we report for the first time the occurrence of subsurface manganese-dominated Frutexites preserved within carbonate veins in ultramafic rocks. To determine the biogenicity of these putative biosignatures, we analyzed their chemical and isotopic composition using Raman spectroscopy and secondary ion mass spectroscopy (SIMS). These structures were found to contain macromolecular carbon signal and have a depleted 13C/12C carbon isotopic composition of –35.4 ± 0.50 ‰ relative to the entombing carbonate matrix. These observations are consistent with a biological origin for the observed Frutexites structures.
Omeprazole increases survival via different mechanisms in two rat models of liver injury
Authors: Kotsuka Masaya , Hashimoto Yuki , Nakatake Richi , Okuyama Tetsuya , Hatta Masahiko , Yoshida Terufumi , Okumura Tadayoshi , Nishizawa Mikio , Kaibori Masaki , Sekimoto Mitsugu 
Published: May 2021

Abstract
Omeprazole (OMZ) is a proton pump inhibitor (PPI) that is used to reduce gastric acid secretion, but little is known about its possible liver protective effects. This study investigated whether OMZ has beneficial effects in rat septic models of lipopolysaccharide (LPS)-induced liver injury after D-galactosamine (GalN) treatment and 70% hepatectomy (PH), and to determine the mechanisms of OMZ in an in vitro model of liver injury. In the in vivo models, the effects of OMZ were examined 1 h before treatment. OMZ increased survival and decreased tumor necrosis factor-alpha, inducible nitric oxide synthase, cytokine-induced neutrophil chemoattractant 1, interleukin (IL)-6, and IL-1β mRNA expression, and increased IL-10 mRNA expression in the livers of both GaIN/LPS- and PH/LPS-treated rats. Necrosis and apoptosis were inhibited by OMZ in GaIN/LPS rats, but OMZ had no effects on necrosis in PH/LPS rats. Primary rat hepatocytes were treated with IL1-β in the presence or absence of OMZ (in vitro model). OMZ inhibited iNOS induction partially through suppression of NF-κB signaling in hepatocytes. Furthermore, OMZ inhibited the induction of several inflammatory mediators, resulting in the prevention of LPS-induced liver injury after GalN liver failure and PH, although OMZ showed different doses and mechanisms in the two models.
Financial Incentives for Preventing Postpartum Return to Smoking (Fipps): Study Protocol for a Three-Arm Randomised Controlled Trial
Authors: Ussher Michael , Best Cath , Lewis Sarah , McKell Jennifer , Coleman Tim , Cooper Sue , Orton Sophie , Bauld Linda 
Published: May 2021

Abstract
BackgroundFinancial incentives are an effective way of helping women to stop smoking during pregnancy. Unfortunately, most women who stop smoking at this time return to smoking within 12 months of the infant’s birth. There is no evidence for interventions that are effective at preventing postpartum smoking relapse. Financial incentives provided after the birth may help women to sustain cessation. This randomised controlled trial will assess the effectiveness and cost effectiveness of financial incentives to help women who are abstinent from smoking at end of pregnancy to avoid return to smoking up to 12 months postpartum. MethodsThis is a UK-based, multi-centre, three-arm, superiority, parallel group, individually randomised controlled trial, with 1:1:1 allocation. It will compare the effectiveness of two financial incentive interventions with each other (one intervention for up to three months postpartum offering up to £120 of incentives, the other for up to 12 months postpartum with up to £300 of incentives) and with a no incentives/usual care control group. Eligible women will be between 34 weeks gestation and two weeks postpartum, abstinent from smoking for at least four weeks, have an expired carbon monoxide (CO) reading <4 parts per million (ppm), aged at least 16 years, intend remaining abstinent from smoking after the birth and able to speak and read English. The primary outcome is self-reported, lapse-free, smoking abstinence from the last quit attempt in pregnancy until 12 months postpartum, biochemically validated by expired CO and/or salivary cotinine or anabasine. Outcomes will be analysed by intention-to-treat and regression models used to compare the proportion of abstinent women between the two intervention groups and between each intervention group and the control group. An economic evaluation will assess the cost-effectiveness of offering incentives and a qualitative process evaluation will examine barriers and facilitators to trial retention, effectiveness and implementation. DiscussionThis pragmatic randomised controlled trial will test whether offering financial incentives is effective and cost-effective for helping women to avoid smoking relapse during the 12 months after the birth of their baby. Trial registrationInternational Standard Randomised Controlled Trial Number: 55218215. Registered retrospectively on 5 th June 2019.
The Spatial Distribution Characteristics of Typical Pathogens and Nitrogen and Phosphorus in the Sediments of Shahe Reservoir and their Relationships
Authors: Sun Wen , Yang Ke , Li Risheng , Chen Tianqing , Xia Longfei , Wang Zhao , Sun Xubo 
Published: May 2021

Abstract
Using samples collected in Shahe Reservoir in the upper North Canal in China, this research analyzes the structure of a microorganism group in sediment and the gene expression levels of two typical pathogenic bacteria (Escherichia coli and Enterococcus), and their relationship with environmental factors including total nitrogen (TN) and total phosphorus (TP). The study of samples collected from the surface (0–20 cm) and sediment cores shows that the absolute gene expression level of E. coli in in horizontal distribution in the sediment is higher than the relative gene expression level in the downstream of the reservoir and contaminated area. In vertical distribution, the absolute gene expression level of the two pathogenic bacteria in the sediment tends to decrease with increasing depth, although the relative gene expression level has its highest value at 10–30 cm depth. The relative gene expression level of the two pathogenic bacteria is much greater in the sediment of Shahe Reservoir with the structure of horizontal groups including Clortridium sensu stricto, unclassified Anaeroineaceae, and Povalibacter, while Anaeroineaceae is much more abundant in the group structure of the vertical distribution. Pearson correlation analysis suggests positive correlation in horizontal distribution for E. coli and TN and TP (P < 0.05) and for Enterococcus and TP (P < 0.05). The results clearly show that the amount of pathogenic bacteria in the sediment in Shahe Reservoir is most likely due to water eutrophication.
Network-based Inference of Hub Genes in Epithelial Membrane Protein 2-treated Human RPE cells
Authors: Wan Hua , Zhang Wei , Gao Wei , Lu Xiang , Chen Feng 
Published: May 2021

Abstract
BackgroundsIdentification of hub genes (HGs) using transcriptome data of epithelial membrane protein 2 (EMP2) treated human retinal pigment epithelial cells (hRPECs) samples was helpful to accurately evaluate the functional relevance of genetic alterations in activity proteins (APs) in these cells.ResultsWe performed differential expression genes (DEGs) analyses of public RNA-seq transcriptome data of EMP2 treated hRPECs, victor control (VC) and wild type (WT) hRPECs. VIPER (Virtual Inference of Protein activity by Enriched Regulon analysis) was used to convert DEGs outcomes to APs signatures and ARACNE (Algorithm for the Reconstruction of Accurate Cellular Networks) was used to construct transcription regulatory networks (TRNs) to identify hub genes (HGs). ConclusionsIn addition to identifying a significant fraction of DEGs among EMP2-OE groups and EMP-KD groups when compared to VC or WT groups, respectively, we also accurately inferred aberrant TGNs and found several HGs induced by EMP2-overexpressed hRPECs under hypoxia. Thus, we raise a hypothesis that EMP2 may regulate hRPECs angiogenesis via a PDGFA regulatory network, which would help to understand the complex biology of angiogenesis in EMP2 and hypoxia treated hRPECs.