bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Significance of Oligohydramnios in Patients with Preterm Premature Rupture of Membranes
Authors: Chistyakova O. M. , Gureeva L. V. , Radkov O. V. 
Published: June 2021

Background. Preterm premature rupture of membranes (PPROM) is one of the main causes of perinatal morbidity and mortality. Associated oligohydramnios may further exacerbate the condition leading to intra-amniotic inflammation and adverse obstetric and perinatal outcomes in preterm labor.Aim of the research. To determine an impact of oligohydramnios on patients with preterm premature rupture of membranes.Materials and methods. We performed a retrospective analysis of two groups of patients with PPROM: 56 patients with oligohydramnios were included in the main group, 111 patients without oligohydramnios were included in the control group. The gestational age varied from 24+0 weeks to 33+6 weeks. Amniotic fluid index, endocervical culture, leukogram and neutrophil-to-lymphocyte ratio (NLR), serum procalcitonin and C-reactive protein levels were assessed in all participants.Results. We witnessed a plethora of consequences in the group of women with PPROM and oligohydramnios: shorter latent phase, higher incidence of clinical chorioamnionitis, antenatal fetal distress, higher levels of C-reactive protein, leukocytes, neutrophils and NLR, lower level of lymphocytes, and increased growth of potentially pathogenic cervical flora. Moreover, the patients with oligohydramnios demonstrated a significantly higher rate of cesarean delivery. The combination of PPROM and oligohydramnios also take a toll on the condition of the newborns: they have lower 5-minute Apgar score and higher prevalence of respiratory distress syndrome, congenital pneumonia, and necrotizing enterocolitis. Furthermore, newborns from the main group are more likely to be admitted to the neonatal intensive care unit, compared with newborns from the control group.Conclusion. Oligohydramnios in PPROM is associated with a dramatic rise of numerous complications affecting both the women and the newborns.
Optimization of Hypoxic Brain Injuries Diagnostics in Full-Term Newborns
Authors: Panova M. S. , Panchenko A. S. , Mudrov V. A. 
Published: June 2021

The problem of early diagnosis of the central nervous system damage in newborn before the onset of clinical symptoms remains relevant at the present time.The aim of the study was to optimize the hypoxic brain damage diagnosis in full-term newborns by analyzing the concentration of cytokines in the umbilical cord blood.Materials and methods. During the first stage of the study, a prospective analysis of concentrations of interleukins (IL-1β, IL-4, IL-6, IL-8, IL-10), TNF-α and neuron-specific enolase (NSE) in the umbilical cord blood serum of full-term newborns was performed. The second stage of the study included the retrospective analysis of clinical data and instrumental research methods. The main method for diagnosing in the development of hypoxic brain damage in newborns was neurosonography.Results. The development of hypoxic brain damage is evidenced by the concentration of IL-1β over 30.3 pg/ml, IL-4 – over 1.7 pg/ml, IL-6 – over 79.4 pg/ml, IL-8 – over 107.7 pg/ml, NSE – more than 10.3 ng/ml and TNF-α – more than 1.6 pg/ml in umbilical cord blood.Conclusion. The results of the study confirmed that the comprehensive assessment of the cytokines concentration in the umbilical cord blood improves the hypoxic brain damage diagnosis in newborns. Analysis of the level of these markers immediately after the birth will optimize the management tactics of newborns who have undergone hypoxic exposure in antenatal and intranatal period.
The Commercialization of Genetic Research: A Pilot Study
Authors: Bairova T. A. , Nemchinova N. V. , Sambyalova A. Yu. 
Published: June 2021

With the development of molecular genetics, the field of personalized medicine based on genetic data has been growing at a phenomenal pace. Genetic tests can identify health risks, ancestry, and genealogy, as well as the prediction of drug responses. However, very limited research exists about the marketing practices of companies, which promote and sell DNA ancestry and health-related genetic tests directly to the public.Aim. To evaluate the awareness and attitude about genetic testing in the population of a large industrial city in Russia (on the example of Irkutsk).Materials and methods. A total of 305 respondents – 265 of them were students of higher educational institutions of Irkutsk. The study was conducted on condition of anonymity. The questionnaire was available on the Internet on the basis of the Google Forms service. All basic concepts were explained to the participants during the survey.Results. 94.1 % are interested in conducting genetic testing on a commercial basis. Of the total number of survey participants, 72.8 % expressed a desire to undergo the analysis “Hereditary predisposition to diseases”, 61 % – “Monogenic diseases”, 52.1 % – “Ethno”. In addition, out of the total number of respondents surveyed, 36.7 % want to undergo genetic testing for research: features of metabolism and food intolerance “Diet”, 22 % – susceptibility to injuries and speed of recovery of physical form “Sport”, 18 % – to hereditarily determined susceptibility to drugs “Pharmacy”. It follows from the answers that the greatest interest among the surveyed people is the determination of predisposition to cardiovascular diseases – 72.5 %, to Alzheimer’s disease – 48.3 % and diabetes mellitus – 40.3 %.Conclusion. The results obtained indicate an interest in the study of predisposition to cardiovascular and neurodegenerative diseases. There is a high need to analyze the assessment of the clinical usefulness of genetic research, to assess the impact of research results on human behavior and the system of regulation of genetic testing in healthcare in general.
Antithrombotic Therapy in Elderly Patients with Atrial Fibrillation: The State of the Problem in the Real Clinical Practice of a Family Medicine Doctor
Authors: Kanat кyzy Bazira , Kinderbaeva N. K. , Turdaliyev S. O. , Mahmudova Zh. A. , Kundashev U. K. , Mamatov S. M. 
Published: June 2021

Introduction. The research aimed at studying the efficacy and safety of anticoagulant therapy in patients with atrial fibrillation (AF), especially in older age groups, is now increasingly relevant.The aim of the study is to analyze the situation with prescribing anticoagulant therapy in elderly and senile persons with atrial fibrillation in real clinical practice and to demonstrate the possibility of improving the quality of observation and management of a group of patients as part of the work of a specialized team.Materials and methods. A total of 2,770 medical records of outpatient patients with atrial fibrillation were studied for the period from 2017 to 2019. Of this number, 320 patients with AF of nonvalvular etiology were selected, the average age of which was 70.3 ± 8.15 years. There were 270 women and 50 men. An observational prospective study in 45 elderly and senile patients with AF of non-valvular etiology was carried out by a team of specialized doctors for 12 months.Results. Of the 301 patients, anticoagulant therapy was prescribed to 166 (55.1 %), of which only 17 (10.2 %) people received proper anticoagulant therapy. The excessive activity was observed in 114 (37.9 %) patients, who underwent antiplatelet therapy with aspirin, and 21 (7.0 %) patients remained without any treatment with anticoagulants nor antiplatelet agents. Although, in the case of both, prescribing aspirin and not prescribing, anticoagulants have been indicated. In the prospective part of the study (for 12 months), all 45 patients continued to take anticoagulants and were systematically monitored. The INR in the target range over 60 % of the time was achieved in 37 % of patients receiving warfarin therapy.Conclusion. In the actual clinical practice of Kyrgyzstan family medicine centers, older patients with atrial fibrillation receive inadequate antithrombotic therapy. The main drug of choice for specialists remains warfarin, a therapy that can be recognized as adequate only in a small number (16 %) of patients. The ability to improve the quality of surveillance and management of a group of patients with AF and high adherence to treatment was demonstrated by the work of a specialized team of doctors.
DIŞ POLİTİKA ANALİZİNDE GELENEKSEL REALİST TEORİYİ SORGULAYAN YAKLAŞIMLARIN ORTAYA ÇIKIŞI ÜZERİNE BİR İNCELEME
Authors: YALÇIN Resul 
Published: June 2021

Özet
Dış Politika (DP), en genel anlamıyla farklı aktörlerin, özellikle de devletlerin, uluslararası sistem içerisinde birbirileriyle olan etkileşimleri ve takındıkları tavırların tümü olarak tanımlanabilir. Dış Politikanın gelişimi ulusal sınırlar içerisinde gelişen düşüncelerden, başka devletlerin politikalarından, tavırlarından veya belirli jeopolitik amaçları gütme planlarından etkilenir. Dış Politika Analizi (DPA) de en genel anlamıyla bu farklı aktörlerin, özellikle de devletlerin, dinamik uluslararası sistem içerisinde birbirleriyle kurdukları ilişkileri ve bu ilişkilerin uygulamalarını inceler. DPA disiplininin gelişim süreci içerisinde doğan her yeni yaklaşım farklı bir bakış açısına sahiptir. Bu yüzden dış politika, Uluslararası İlişkiler disiplinin nerdeyse bütün ana yaklaşımları için olduğu kadar, disiplinler arası bir inceleme gerektirmektedir. DPA disiplinin merkezinde, karar vermeyi, bireysel karar vericileri, dış politikayı ve alınan kararların çıktılarını etkileyen süreç ve koşulların incelenmesi yer alır. Bu nedenle, DPA doğal olarak yalnızca devletin resmi karar alma mekanizmasına dâhil olan aktörleri değil, aynı zamanda devletin dış politikası üzerinde etkisi olan ulus-altı ve ulus-ötesi unsurları da inceleme konusu yapar.
Bu çalışma merkezine “Günümüze dek gelen süreç içerisinde Dış Politika Analizine yönelik ne tür yaklaşımlar gelişti ve gelişen bu farklı yaklaşımların özelde Dış Politika Analizine, genelde ise Uluslararası İlişkiler disiplinine katkıları nelerdir?” sorusunu almaktadır. Bu çalışma, merkezine aldığı sorunsalı açıklamaya çalışırken bu yaklaşımların ortaya çıkışını zorunlu kılan faktörlerin genel bir betimlemesini yaparak dış politikanın nasıl bir yaklaşımla daha iyi analiz edilebileceği tartışmalarına da değinerek DPA alanının temel kusurunun ne olduğunu belirterek bitirecek.
On the growth of series in system of functions and Laplace-Stieltjes integrals
Authors: Sheremeta M.M. 
Published: June 2021

For a regularly convergent in ${\Bbb C}$ series $A(z)=\sum\nolimits_{n=1}^{\infty}a_nf(\lambda_nz)$ in the system ${f(\lambda_nz)}$, where$f(z)=\sum\nolimits_{k=0}^{\infty}f_kz^k$ is an entire transcendental function and $(\lambda_n)$is a sequence of positive numbers increasing to $+\infty$, it isinvestigated the relationship between the growth of functions $A$ and $f$ in terms of a generalized order. It is proved that if$a_n\ge 0$ for all $n\ge n_0$,
$\ln \lambda_n=o\big(\beta^{-1}\big(c\alpha(\frac{1}{\ln \lambda_n}\ln \frac{1}{a_n})\big)\big)$
for each $c\in (0, +\infty)$ and $\ln n=O(\Gamma_f(\lambda_n))$ as $n\to\infty$ then
$\displaystyle\varlimsup\limits_{r\to+\infty}\frac{\alpha(\ln M_A(r))}{\beta(\ln r)}=\varlimsup\limits_{r\to+\infty}\frac{\alpha(\ln M_f(r))}{\beta(\ln r)},$
where $M_f(r)=\max\{|f(z)|\colon |z|=r\}$, $\Gamma_f(r):=\frac{d\ln M_f(r)}{d\ln r}$ and positive continuous on $(x_0, +\infty)$ functions $\alpha$and $\beta$ are such that $\beta((1+o(1))x)=(1+o(1))\beta(x)$, $\alpha(c x)=(1+o(1))\alpha(x)$ and$\frac{d\beta^{-1}(c\alpha(x))}{d\ln x}=O(1)$ as $x\to+\infty$ for each $c\in(0, +\infty)$.\A similar result is obtained for the Laplace-Stieltjes type integral $I(r) = \int\limits_{0}^{\infty}a(x)f(rx) dF(x)$.
Do policymakers use social media for policy design? A Twitter analytics approach
Authors: Rathore Ashish Kumar , Maurya Dayashankar , Srivastava Amit Kumar 
Published: June 2021

Social media has been used widely for communicating information, awareness, and promote public policies by government agencies. However, limited attention has been paid to the use of social media in improving the design of public policies. This paper explores to what extent citizens' responses/opinions expressed on social media platforms contribute to policy design. The paper analyzes discussion about the 'Ayushman Bharat' scheme on Twitter through social media analytics techniques (e.g., content analytics) and then traces the change in policy design over two years. To validate findings from Twitter data, and assess the evolution in policy design, we conducted in-depth interviews with experts and extensive document analysis. The paper reveals that consistently similar issues were raised by the experts in the past as well as by the citizens in the current scheme. However, over the period, the policy design has not changed significantly. Therefore, despite a strong social media presence, its optimum use to improve policy effectiveness is yet to be achieved. The paper contributes by exploring the role social media can play in the public policy process and policy design in developing countries' contexts and identifies gaps in existing social media strategies of public agencies.
STATE OF WASTEWATER TREATMENT TECHNOLOGIES IN UKRAINE AND THE WORLD
Authors: Yu. Sniezhkin , Petrova Zh. , Paziuk V. , Novikova Yu. 
Published: June 2021

In sewage treatment plants, sludge is formed during wastewater treatment, in addition to treated water. They are dumped on silt sites, which occupy large areas and almost all overcrowding. The content of large amounts of minerals and toxic substances in sediments leads to the deterioration of underwater waters and land, which in turn leads to the deterioration of ecology and life in Ukraine. An urgent task in Ukraine is to create a comprehensive processing of sludge, which includes economic, technological, social and environmental aspects.
The main methods of sludge disposal are use in agriculture, landfilling, incineration and dumping into the sea or ocean. The country is gradually trying to abandon the burial. European Union countries also process sludge aerobically and anaerobically. During these processes, components of organo-mineral fertilizers are created that can be used in agriculture. As fertilizers, sludge is composted, stabilized and pasteurized. Combustion of sludge allows to obtain a substitute for coal and oil. To increase the heat of combustion and improve combustion parameters to sludge sludge add coal, biomass. Low-temperature pyrolysis of sewage sludge and household waste, which allows to obtain "crude oil". One of the methods is processing in biogas plants to obtain both biogas and environmentally friendly fertilizers. To increase the efficiency of treatment and reduction of sludge disposal of used stagnation-ments vermiculture.
Analysis of the literature allows us to conclude that there are methods of disposal of sludge, which have become widespread in various countries around the world, such as fertilizers, alternative fuels, landfills and others. When disposing of sludge, it is possible to produce biogas, electricity and heat, which reduces energy costs for the process.
Complaints Information System for the Polytechnic of South Aceh
Authors: IHSAN ARINAL , Ben Hasbaini , Fardiansyah  , Putra D.S , Asmaidi  
Published: June 2021

The industrial revolution 4.0 is a hot topic discussed only among academics and industry. Of course, this condition is a positive thing that shows that people have started to care about utilizing technology that is developing very rapidly today. South Aceh Polytechnic (POLTAS) as a vocational higher education institution, of course, must be consistent in making innovations in improving services to stakeholders. The quality and quality of service to stakeholders must of course be maintained so that input, criticism, and suggestions from them are one of the most important factors in creating a safe and comfortable academic atmosphere for higher education, especially POLTAS. The formulation of the problem in this study is how to build and simulate the results of an information system that can adapt dynamically in carrying out the political services of South Aceh provided to stakeholders. The purpose of this research is to build a Complaints Information System for the Polytechnic of South Aceh (SIAPA). This research is also part of the POLTAS Internal Quality Assurance System (SPMI) which is managed independently assigns to control and improve quality in the implementation of higher education in a planned manner (with designed) and sustainable (sustainable). This type of research is applied research with case studies at the South Aceh Polytechnic. The research procedure is in several stages, namely planning, analysis, design, development, testing, implementation, simulation of results, and evaluation.
The Development of i-TACwim for Academic Calender Management in Polytechnic
Authors: Raja Norhafiza binti Raja Rosly  , Zareena binti Rosli  , Aishah binti On  , Noor Muzlinda binti Mat Hashim  
Published: June 2021

The need for automated and intelligent technology is a need nowadays. Even in the academic system, these technologies such as mobile apps and intelligent web system is essential for effective communication. However, the method of dissemination of information regarding academic calendar in Polytechnic is conducted conventionally thru hardcopy or downloaded document from institutional portal. The conventional method was found less practical in use which the lecturers often faced problems in their daily academic activities. Thus, namely as i-TACwim aims to design and develop an intelligent academic calendar that able to distribute real-time information regarding academic activities. The application also serves to send notifications to users according to important dates related to the International Standards Organization (ISO) procedures. This project applies repetitive development process adapted from agile Model consists of six phases. The development of this project is using YII2 Framework PHP of the system and interface, MySQL Server for the database and Firebase as the technology used for push notification. As a result, the i-TACwim application is a need and consider as an alternative to manual academic calendar to be used as the polytechnic intelligent academic calendar among the polytechnic community. User acceptance pilot testing will be conducted via questionnaire to form in order to show the capability and deliverables of this project.
POPULATION DYNAMICS OF NORMAL AND CANCER CELLS UNDER RADIOTHERAPY
Authors: Farayola Musiliu Folarin , Shafie Sharidan , Mohd Siam Fuaada 
Published: June 2021

The use of the improved cancer treatment model predicted the population changes in the normal and cancer cells during radiotherapy.
The simulated radiation doses are 15 Gy, 18 Gy, 20 Gy and 24 Gy administered 5 times for each dose.
The population of the cancer cells reduced from 40 % of the carrying capacity to 10.72%, 23.25 %, 1.61 % and 3.72 % of the carrying capacity for the respective doses.
The population of the normal cells reduced from 70% of the carrying capacity to 65.50%, 62.48%, 68.49% and 67.59% of the carrying capacity for the respective doses.
During the no treatment stage (0 Gy), the model predicted an increase in the population of cancer cells and a decrease in the population of normal cells.
A Comparative Analysis of the Online Scheduling System
Authors: Noor Asma Husain  , Siti Musleha Ab Mutalib  , Noor Hayati Mohd Zain  , Nor Hidayah Mohd Nor Hussain  , Mohd Khalid Mokhtar  , Nurul Iman Nor Hisham  
Published: June 2021

Scheduling system is developed based on customers, individuals or organizational preferences in order to create an efficient and effective management of arrangement in prioritization, tasks, place and time. Some of scheduling systems will integrate a database for effective access of editing, viewing and recording amount of data. However, poor scheduling practices would cause undesirable time redundancy and inefficient process just to schedule a timetable for the lecturers and students. Poor scheduling also can cause a misunderstanding between lectures such as double-assignations of lectures, cancellations of presentations, clash in class schedule, prolonged postponement as well as inefficiency in terms of resources and time. A good scheduling system could generate optimal presentation of timetables and enable a direct interaction between lecturers and administration staff that will take into account all the constraints such as to check availability of time and place of events and real-time updates that will help data handling accuracy, cost effective and efficient time management. Therefore, this study will make a comparison and execute a standard process of scheduling framework for future practice in academic industry. This paper presents a practical method for making a comparison based on the studies on existing scheduling system.
UPAYA PEMANFAATAN HALAMAN RUMAH SEBAGAI LAHAN PERTANIAN BUDIDAYA TANAMAN UNTUK MENSEJAHTERAKAN MASYARAKAT PADA MASA COVID 19 DI KELURAHAN TELUK PINANG
Authors: Zulkifli.  
Published: June 2021

Masa pandemi COVID-19 memaksa setiap orang untuk tinggal di rumah demi memutus mata rantai penyebaran virus. Kondisi ini tidak serta merta membuat para petani menjadi tidak produktif. Beragam aktivitas bisa dilakukan, khususnya yang bisa menopang kebutuhan pangan rumah tangga. Salah satu yang bisa dilakukan adalah berkebun sayuran organik di pekarangan rumah.Pekarangan merupakan suatu lahan yang berada di sekitar rumah. Hampir semua rumah memiliki pekarangan atau halaman. Beranekaragam tanaman yang dapat di tanam pada halaman rumah yaitu Tanaman Sayuran, Tanaman Pagar, Tanaman Buah, Tanaman Obat dan bumbu dapur,serta Bunga. Apabila dikelola dengan baik maka lahan ini dapat memberikan keuntungan bagi pemilik. Metode yang dilakukan yaitu dengan cara diskusi dan wawancara. Dari hasil wawancara tersebut dapat diketahui bahwa masyarakat di Kelurahan Teluk pinang dalam keterbatasan lahan yang ada pada masa covid -19 di halaman rumah sudah ada namun hanya saja bvelum banyak varietas sehingga hanya untuk konsumsi saja.
Pola Komunikasi Edukasi di Koperasi Unit Desa dan di Koperasi Pondok Pesantren
Authors: Wawan Lulus Setiawan  
Published: June 2021

The purpose of this research is to describe the differences between the pattern of educational communication in the Village Unit Cooperatives (KUDs) and that in the Traditional Iskamic Boarding School Cooperatives (Kopontrens) in West Java Province, Indonesia. The research was carried out with qualitative approach on 12 KUDs and 12 Kopontrrens in West Java Province, Indonesia. The idea of research was based on the International and Indonesian Cooperative Principles which obliges the cooperatives to arrange cooperative education program for the cooperative’s members and based on the facts of cultural background differences between KUDs and Kopontrens. The result of the research indicated that educational communication in the Kopontrens is stronger than that in the KUDs because the process of educational communication process in the Kopontrens has become a standardized educational program, so that the elements of communication process consisting of “who says what to whom in which channel, in what effect and environtment” has become a package of the educational communication curriculum in Kopontrens. This could explain why the members’ participation in the Kopontrens is better than that in the KUDs. This result of the study could give social and policy implication for developing method of members educatin in the KUDs in Indonesia.