bluuebunny/crossref_metadata_2025_split huggingface dataset:
UPGRADING MINAT WIRAUSAHA SISWA DALAM RANGKA OPTIMALISASI POTENSI DAERAH YANG DALAM MEMBANGUN KEMANDIRIAN EKONOMI
Authors: Edy Irwan Christanto , Marsono Shandy , Utama Heriyanta Budi 
Published: January 2021

Pengangguran merupakan permasalahan sosial yang membutuhkan penanganan yang serius karena akan berdampak pada permasalahan sosial lainnya seperti kriminalisme, kemiskinan dan penyakit masyarakat. Salah satu solusi mengatasi pengangguran adalah program kewirausahaan. Program kewirausahaan lebih baik kalau dimulai dari jenjang pendidikan formal, dan jiwa wirausaha harus ditanamkan kepada siswa sejak dini. Pendidikan kewirausahaan berbasis sekolah sangat tepat diterapkan pada jenjang pendidikan SMK, karena lulusan SMK merupakan lulusan siap kerja di masyarakat. PKM bagi siswa SMK Negeri 7 Surakarta ini bertujuan untuk memberikan bekal pengetahuan, dan ketrampilan yang akan meningkatkan sikap dan motivasi siswa dalam berwirausaha. Kewirausahaan siswa merupakan kewirausahaan yang mengoptimalkan kemampuan siswa untuk berinovasi dan berkreasi dalam membangun bisnis sesuai dengan kompetensinya. Dalam kewirausahaan siswa ini dukungan prasarana, guru, karyawan, komite menjadi kunci dalam pendidikan kewirausahaan di sekolah SMK. Metode yang digunakan dalam kegiatan ini dengan memberikan pelatihan dan pendampingan pada siswa SMK. Dalam kegiatan ini Tim pelaksana bermitra dengan SMK Negeri 7 Surakarta Jawa Tengah. Kegiatan ini memberikan hasil yaitu (1) peningkatan pengetahuan berwirausaha (2) peningkatan motivasi dan minat siswa untuk wirausaha, (3) meningkatnya ketrampilan dalam mengelola usaha. Kegiatan ini akan sangat memberikan manfaat bagi siswa sebagai calon wirausaha yang berhasil. Kata kunci : Kewirausahaan, Siswa, Pelatihan dan Pendampingan, Sekolah Menengah Kejuruan (SMK)
Тризомия на 16-та хромозома във фетус – клиничен случай
Authors: Яхя Диннар , Цветкова Мария , Левкова Мария , Хачмериян Мари , Ангелова Людмила 
Published: January 2021

Хромозомните аберации стоят в основата на над половината от случаите на ранни спонтанни аборти, като най-голям дял сред тях се дължи по-конкретно на тризомиите по автозоми.
Представяме случай на двойка, консултирана по повод спонтанен аборт в пета гестационна седмица – трета бременност и втори последователен спонтанен аборт от настоящия партньор. Проведен е цитогенетичен анализ на култивирани фибробласти от абортивна тъкан с анализ на 11 метафазни пластинки, оцветени диференциално чрез GTG-бендинг. Анализирани са и лимфоцитни култури от периферна кръв на двамата родители с цел изключване на балансирано хромозомно преустройство. Проведена се също пре- и постаналитична медико-генетична консултация.
При фетуса е установен кариотип 47,XY,+16, пълна форма, резолюция 150 бенда. Цитогенетичният анализ при родителите потвърди нормален кариотип – 46,ХХ при майката и 46,XY,22pstk+ps+ при бащата, резолюция 400-550 бенда по GTG-бендинг диференциално оцветяване.
Потвърждава се спорадично възникнала, несъвместима с живота хромозомна аберация във фетуса, възникнала по време на гаметогенеза или много ранно онтогенетично развитие. Рискът за повторение при следваща бременност се оценява като нисък, равен на популационния.
Настоящата публикация има за цел да демонстрира съвременното приложение на цитогенетичния анализ при изясняване етиологията на спонтанно настъпили аборти и свързаната с това медико-генетична консултация. На фона на напредъка на молекулярно-генетичните методи, които обаче все още не се предлагат достатъчно масово в страната, това е един добре познат, икономически достъпен и нерядко използван, въпреки недостатъците си метод.
Representasi Santri dalam Trailer Film The Santri
Authors: Sartika Anita 
Published: January 2021

PBNU is working a film called The Santri which is expected to be media of da’wah. However, not long after the trailer was released, contra opinion appeared among the fellow muslims. Those who deny consider The Santri does not represent the ideal of santri. In fact, PBNU has been known as an Islamic organization with the highest number of pesantren. Therefore, the representation of santri on this trailer should be the best representation. Thus, this article aims to analysis how santri is represented. The researcher uses semiotic method which revealed the meaning of signs by Charles Sanders Peirce. The analysis shows there are several scenes that enable the representation of santri to get the pros and cons because they related with legisign-type objects, which are related to Islamic law. Although there are scenes that represent students well, such as having high dreams and diligently worship.
Epidemiology, index of accuracy, histological structure, year-by-year lethality and survival of patients with malignant melanoma. Population study – part I
Authors: Merabishvili Vakhtang , Merabishvili Elvira 
Published: January 2021

Malignant melanoma of the skin (MMS) is one of the many types of skin tumors that consists of three layers – the epidermis, dermis and hypoderma. MMS develops from melanocyte cells located in the basal layer of the epidermis and producing the pigment melanin. The melanocyte is a dangerous and vindictive cell, it remembers all sunburns and accumulates them. It is the melanin that gives the skin a brown hue as a result of insolation. It also determines the skin color of African-Americans. Birthmarks are also examples of a cluster of melanocytes.
In the structure of cancer incidence in economically developed countries, MMS occupies a fairly modest place, but over the past 30 – 40 years, there has been an unfavorable trend.
In Russia, MMS is not even among the top ten main localities of malignant tumors, its even smaller share in the overall structure of malignant tumors in Russia was in the 80s of the XX century. Until 1982, state reporting did not provide a set of data on the MMS in the USSR and in Russia, including. At our suggestion, in 1982, the Ministry of health of the USSR decided to allocate a separate line in the state reporting for malignant tumors.
In this study, along with assessing the prevalence of MMS in the world and Russia, we focused on the in-depth development of materials for the North-Western Federal district, mainly based on data from the established population cancer registry (PCR).
For many years, the analysis of cancer incidence and survival of patients with malignant tumors was carried out by us on the basis of the PCR of St. Petersburg. In February 2019, the first cancer registry at the Federal district level appeared in Russia – PCR of the NWFD of the Russian Federation. As of 01.02.2019, the PCR of the NWFD of the Russian Federation had more than 1 million cases of malignant tumors (1,067,661), including more than 20,000 (21,428) with MMS (2.0%). The PI on the Federal district level allows for in-depth development of the dynamics of localization and histological structure of malignant tumors fourth sign of ICD–10 to study the characteristics of prevalence and survival of patients malignant tumors in any part of the localization structures (lips, ear, trunk, upper and lower extremities, etc.) that cannot be done on the basis of public reporting, and provide analysis of survival of patients of any localization.
Specificity of aminergic status in skin and tumor of C57BL/6-PlautmI.IBug-This Plau6FDhu/GFDhu mice with B16/F10 melanoma
Authors: Kit Oleg , Frantsiyants Elena , Kaplieva Irina , Surikova Ekaterina , Neskubina Irina , Bandovkina Valeriya , Trepitaki Lidiya , Cheryarina Natalia , Pogorelova Juliya , Nemashkalova Lyidmila , Sidorenko Yuri 
Published: January 2021

Background. Systems of plasminogen activation and biogenic amines are involved in carcinogenesis, but their relationship has not been established.
Aim – study of the quantitative specificity of biogenic amines in the skin and melanoma in urokinase-gene knockout mice.
Materials and methods. Levels of catecholamines, histamine, serotonin and 5-hydroxyindoleacetic acid (HIAA) were determined by ELISA in the skin and В16/F10 melanoma of urokinase (uPA) -gene knockout mice of both genders (n=24); С57ВL/6 mice (n=64) were controls (C).
Results. Differential characteristics of melanoma development in uPA-deficient mice included: an earlier onset of the primary tumor and its slow growth, more pronounced in females, in combination with hemorrhages in the lungs of males and solitary metastases in the lungs of females. This was facilitated by higher levels of norepinephrine in the skin of males/females – by 4.8/4.9 times, histamine – by 3.6/1.7 (p<0.05) times and serotonin – by 3.4/8.3 times. Dopamine accumulated in melanoma in all uPA-gene knockout mice: in females –1.6 times (p<0.05), in males – 2.1 times higher than in intact skin, with a 2.5 times reduction of norepinephrine in females. Levels of histamine decreased, but exceeded controls: in females – by 1.8 times (p<0.05), in males –by 3.5 times. Levels of serotonin in uPA-deficient females were as high, while in males they were 3.4 times lower than in intact skin.
Conclusions. The specificity of the aminergic system in the skin of uPA-gene knockout mice demonstrated the inhibition of local stress and contributed to the reduction of malignant potential of melanoma by increasing immune properties of the skin.
Evaluation of antitumor activity in strains of a new rotavirus group in Reoviridae family on a model of transplantable murine melanoma
Authors: Kolpakov Sergei , Kolpakova Elena , Zlatnik Elena , Nepomnyashchaya Evgeniya , Novikova Inna , Shulgina Oksana , Sagakyants Alexandr , Sidorenko Yuri 
Published: January 2021

The purpose was to study antitumor effects of the group K rotaviruses strains No. 228 and No. 100 in the experiment on a model of transplantable murine melanoma.
Material and methods. The study included 65 С57Black/6 mice with transplantable B16/F10 melanoma and two strains of the Reoviridae family members characterized as rotaviruses, not belonging to the known groups, with the working title “group K rotaviruses (RVK)”. Animals received RVK in “vaccination” (before tumor transplantation) and “treatment” (after tumor formation) modes. Live and inactivated strains were used. RVK were administered intramuscularly as 0.3 ml of virus-containing culture fluid with at least 5x109 viral particles per 1 ml, with a total of 4 injections. Life span of mice and morphological characteristics of tumors were evaluated.
Results. Injections of both strains increased the survival of tumor-bearing mice by 1.7-1.9 times in 4 of 8 experimental groups, compared to controls. The modes of RVK administration showed some differences: the survival was longer in mice with the “vaccination” mode compared to the “treatment” mode. Morphological changes in tumors were similar after application of both modes and inclued dystrophic changes of tumor cells, formation of extensive necrosis areas, and leukocyte infiltration.
Discussion. Live and inactivated RVK had unidirectional effects implying its association with immunomodulatory action rather than with a direct lytic effect on the tumor.
Conclusions. Both studied strains of rotaviruses in the group K had antitumor effect in the model of transplantable В16/F10 murine melanoma in the «vaccination» mode.
ANALISA ALGORITMA DECISION TREE DAN NAÏVE BAYES PADA PASIEN PENYAKIT LIVER
Authors: Rahman Nadia Tiara 
Published: January 2021

Penyakit liver merupakan penyakit yang disebabkan mengkonsumsi alkohol, pelemakan hati, genitika dari orang tua, diabetes, obesitas pada tubuh dan senyawa kimia yang berasal dari obat-obatan. Liver atau disebut hati merupakan organ manusia yang terbesar dan penting. Penyakit liver dapat melakukan pemeriksaan fisik bagian pada tubuh termasuk paru-paru, jantung, kulit, otak, system saraf, dan perut yang dapat memberikan petunjuk untuk penyebab penyakit hati. Hati berfungsi sebagai detoksifikasi pada racun dalam tubuh. Data yang diteliti merupakan hasil pemeriksaan terhadap data di peroleh sebanyak 583 data dengan 416 orang terdeteksi “positif” penyakit liver dan 167 orang “negative” penyakit liver. Oleh karena itu diperlukan sistem analisa data mining dengan metode Algotitma Decision Tree yang mempunyai nilai optimal akurasi sebesar 70.29% dengan AUC 0.757 sedangkan menggunakan Algotitma Naïve Bayes mempunyai nilai optimal akurasi sebesar 67.05% dengan AUC 0.714. Hasil pembahasan dapat disimpulkan bahwa metode yang memberikan pecahan untuk permasalahan dalam mengindentifikasi penyakit liver ialah Decision Tree (C4.5).
Experimental modeling of technological stages of the formation of a high dimensional-geometric bimetallic casting
Authors: Абашкин Евгений Евгеньевич , Богданова Нина Анатольевна , Жилин Сергей Геннадьевич , Комаров Олег Николаевич , Предеин Валерий Викторович 
Published: January 2021

Изготовление биметаллических деталей позволяет реализовать в них комплекс эксплутационных и механических характеристик, присущих железоуглеродистым и цветным сплавам. Реализация процесса разрабатываемой технологии формирования биметаллического литья с жестким стальным каркасом и поверхностью из цветных сплавов, обладающих большими, чем материал каркаса пластичностью и электропроводностью, возможна за счет применения модернизированного метода литья по выплавляемым моделям. Изменению подвергается стадия изготовления поверхности выплавляемой модели отливки, которая формируется запрессовкой воскообразного порошка в зазор между пресс-формой и стальным каркасом, что позволяет повысить размерно-геометрическую точность литья за счет устранения теплофизических дефектов. Проблемой в реализации такого подхода является упругий отклик материала. В работе решается задача определения технологических параметров формирования воскообразной поверхности выплавляемой модели биметаллической отливки.
The production of bimetallic parts makes it possible to realize in them a set of operational and mechanical characteristics inherent in iron-carbon and non-ferrous alloys. The implementation of the process of the developed technology for the formation of bimetallic casting with a rigid steel frame and a surface made of non-ferrous alloys, which have greater plasticity and electrical conductivity than the frame material, is possible through the use of a modernized investment casting method. The stage of manufacturing the surface of the investment casting model, which is formed by pressing the wax powder into the gap between the mold and the steel frame, is subject to change, which makes it possible to increase the dimensional and geometric accuracy of casting by eliminating thermophysical defects. The problem in implementing this approach is the elastic response of the material. This work solves the problem of determining the technological parameters of the formation of the waxy surface of the melted model of a bimetallic casting.
Piecewise linear approximation of boundary conditions and solutions in problems of 1d nonstationary dynamics of heteromodular elastic media
Authors: Лаптева Анастасия Александровна , Рагозина Виктория Евгеньевна , Дудко Ольга Владимировна 
Published: January 2021

Рассматривается динамика одномерных деформаций разномодульной упругой среды под действием нестационарной граничной нагрузки в режиме «растяжение - сжатие». Исследуются особенности построения кусочно-линейной функции, аппроксимирующей нелинейное краевое условие. Указан критерий выбора узловых точек разбиения аппроксимирующей функции, позволяющий управлять режимами взаимодействия волновых фронтов всех типов в решении краевой задачи. Получена итерационная формула изменения скорости ударной волны в результате ее попутного столкновения с медленными фронтами предварительного растяжения, а также итерационные соотношения для построения поля перемещений на всех стадиях деформирования.
The one-dimensional deformation dynamics in an elastic heteromodular medium under nonstationary boundary loading in the <tension and compression> mode is considered. The features of constructing a piecewise linear approximation of a nonlinear boundary condition are investigated. A selection criterion for the nodal partition points of the approximating function is indicated; it allows us to control the modes of collision between wave fronts of all types when the boundary value problem is solved. An iterative formula for the change in the shock wave velocity as a result of its collision with slow fronts of preliminary tension is obtained; the iterative relations for constructing the displacement field at all stages of deformation are written.
Dynamics of hybrid hardening and viscoplastic beams under explosive effects
Authors: Немировский Юрий Владимирович 
Published: January 2021

Рассматриваются полиметаллические балки постоянного поперечного сечения из наборов упрочняющихся и вязкопластичных материалов с двухсимметричным их расположением в поперечном сечении. Считается, что балки находятся под воздействием нагрузок взрывного типа. Для всех материалов использована модель жестко-вязкопластического деформирования и приняты классические гипотезы деформирования Кирхгофа. Для биметаллических шарнирно-опертых балок получены общие уравнения деформирования и описан метод их решения. Определены остаточные формы динамического повреждения.
We consider polymetallic beams of constant cross-section from sets of hardening and viscoplastic materials with their two-symmetric arrangement in the cross-section. The beams are considered to be subject to explosive loads. For all materials, a rigid-viscoplastic deformation model was used and the classical Kirchhoff deformation hypotheses were adopted. For bimetallic hinged- supported beams, general equations of deformation are obtained and a method for their solution is described. Residual forms of dynamic damage were determined.
To the study of the natural seismic tension of geological massifs
Authors: Зарецкая Марина Валерьевна 
Published: January 2021

Методом блочного элемента проведено исследование блочной структуры, моделирующей геологический массив. Состояние геологической среды описывается уравнениями движениями для однородной, изотропной упругой среды в форме Ляме. Выписаны функциональные и псевдодифференциальные уравнения, получены интегральные представления блочного элемента. Установлены основные тенденции изменения контактных напряжений в зависимости от значений механических характеристик материала блоков и геометрических параметров структуры.
The block structure method is used to study the block structure modeling a geological massif. The state of the geological medium is described by equations of motion for a homogeneous, isotropic elastic medium in the form of a Lame. Functional and pseudo-differential equations are written out, and integral representations of the block element are obtained. The main tendencies of contact stress variation are established depending on the values of the mechanical characteristics of the material of the blocks and the geometric parameters of the structure.
MODEL OF ADHESIVE POLYMER BONDING
Authors: Перельмутер Михаил Натанович 
Published: January 2021

Рассмотрена механическая модель адгезионного соединения полимеров. Полагается, что связи между различными полимерами образованы пучками молекул полимераактиватора адгезии. Учитывается, что молекулы полимера-активатора могут образовывать между соединяемыми полимерами однозвенные и многозвенные связи. Получены кривые деформирования связей в концевой области трещины.
Mechanical model of adhesion polymer bonding is considered. It is assumed that bonds between different polymers are formed by bundles of molecules polymer-activator of adhesion. It is taken into account that molecules of the polymer-activator can form single-link and multi-link bonds between polymers. Deformation curves of bonds in the crack bridged zone are obtained.
On three-constant potentials in polar continua
Authors: Ковалев Владимир Александрович , Мурашкин Евгений Валерьевич , Радаев Юрий Николаевич 
Published: January 2021

В работе рассматривается важная с точки зрения прикладных задач проблема моделирования процессов деформирования материалов со сложным откликом на механические воздействия. Приводятся основные уравнения трехконстантной микроструктурной модели для случая одного полярного директора. Выписана точная форма упругого потенциала, из которой, следуя стандартной схеме, выводятся все необходимые уравнения и граничные условия.
The paper deals with the problem of modeling the processes of deformation of materials with a complex response to mechanical stress. The governing equations of the three-constant microstructural model for the case of one polar director are presented. The exact form of the Helmholtz free energy is written out. The governing equations and boundary conditions are derived by the standard scheme.
On the theory of linear micropolar hemitropic media
Authors: Мурашкин Евгений Валерьевич , Радаев Юрий Николаевич 
Published: January 2021

В статье рассматриваются вопросы применения относительных тензоров при моделирвоании гемитропных микрополярных сред. Вводится определяющая форма микрополярного упругого потенциала. С помощью принципа виртуальной работы получаются определяющие уравнения для силовых и моментных характеристик микрополярного континуума в терминах относительных тензоров. Приводятся уравнения движения микрополярного континуума в терминах относительных тензоров. Выводится финальная форма динамических уравнений для перемещений и микровращений в случае полуизотропной (гемитропной) симметрии.
The paper deals with the application of relative tensors to modeling hemitropic micropolar media. The latter is of crucial importance for biomechanics, mechanics of growing solids and mechanics of metamaterials. The constitutive form of the micropolar elastic potential is discussed. The basic equations of micropolar continuum are derived due to the principle of virtual displacements. Differential equations of the micropolar continuum are given in terms of relative tensors. The final form of dynamic equations for displacements and microrotations in the case of semi-isotropic (hemitropic) micropolar continuum is derived and discussed.
Creencias de contagio casual, estigma y discriminación relacionados al VIH, en adolescentes que asisten a colegios oficiales en áreas urbanas de Panamá
Authors: Murillo Anet , Gabster Amanda , Mendoza Elisa , Cabezas Talavero Gonzalo , Pascale Juan Miguel 
Published: January 2021

Objetivo: Describir la prevalencia y factores sociodemográficos relacionados con las creencias de contagio casual de VIH. Entender los factores que están asociados a estigmas y discriminación hacia compañeros que viven con el VIH en la población adolescente (14-19 años) en centros educativos de nivel media de áreas urbanas de Panamá. Método: Se realizó un estudio de corte transversal con muestreo de conglomerados de dos-etapas, con selección aleatoria en 4 regiones urbanas de Panamá (Panamá, San Miguelito, Colón y Panamá Oeste). Se incluyó estudiantes 14-19 años de centros educativos públicos de educación media entre los meses de junio y agosto de 2015-2018 (una región por año). Se utilizó de regresión logística multivariable con efectos aleatorios. Resultados: Del total de 2466 participantes, el 56.9% era de sexo femenino y el 43.1% de sexo masculino. No se encontró una diferencia significativa entre el sexo de los participantes y la creencia en contagio casual. Después de ajustar el modelo por edad de los participantes, se encontró evidencia de asociación entre participantes de sexo masculino y el estigma (adjusted Odds Ratio [AOR]=1.44, 95% Intervalo de Confianza [IC]:1.14-1.82) y la discriminación (AOR= 2.02 95%CI:1.40-3.07). Al ajustar por sexo y edad de los participantes, se encontró evidencia de asociación entre creencias de contagio casual y estigma reportado (AOR=2.0, IC95%: 1.4-2.9), como también entre estigma y discriminación reportado (AOR=2.2 CI 95%:1.5-3.2). Conclusiones: Los estudiantes entre los 14-19 años que asisten a centros educativos públicos de nivel Media, presentaron una alta prevalencia de creencia de contagio casual del VIH, estigma y discriminación.