bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perception and Adaptation Strategies of Dairy Farmers Towards Climate Variability and Change in West Africa
Authors: Montcho Marthe , Padonou Elie Antoine , Montcho Marlise , Mutua Meshack Nzesei , Sinsin Brice 
Published: June 2021

Abstract
In West Africa, dairy production plays a vital role in the economy and the wellbeing of the population. Currently, dairy production has become vulnerable due to climate variability. The main objective of this study was to investigate dairy farmers’ perceptions and adaptation strategies towards climate change in West Africa. Individual interview and Focus Group Discussions were conducted among 900 dairy farmers. Descriptive statistics and Chi-square test were used to assess dairy farmers’ perception on climate change. Multiple Correspondence Analysis and hierarchical clustering on principal component analysis were used to access the adaptation strategies of dairy farmers. The results revealed that dairy farmers perceived a decrease in the rainy season and the annual rainfall but an increase of the dry season and the annual temperature that affect their activities. Dairy farmers that fed the cattle mainly with natural pastures, crops residues and agroindustrial by-products in the climate zones of Benin, Burkina Faso and Niger, used as climate change adaptation strategies, transhumance in wetland, animal manure to improve fodder production and quality; plants to improve milk production, milk conservation and to treat animal diseases. They sold milk or produced local cheese with the remaining unsold milk. They use crops residues, mineral supplements, herd size reduction; water supply with community pastoral wells and dams, purchase water. Dairy farmers that mainly invested in fodder production and conservation in the climate zones of Mali, sold milk produced to dairies and cheese production units; used plants to improve milk production, pasteurization for milk conservation and veterinary service for animal care. This study provided relevant information for West African policymakers in designing appropriate policies and programs to assist dairy farmers to improve milk production under climate variability and change.
Association of Body Mass Index and Hypoglycaemia with Mortality Rates Among Sepsis Patients: A Retrospective Sub-Analysis of the FORECAST Study
Authors: Tanikawa Atsushi , Kudo Daisuke , Ohbe Hiroyuki , Kushimoto Shigeki 
Published: June 2021

Abstract
Background: Hypoglycaemia at admission is associated with high mortality in sepsis patients. The association of hypoglycaemia and body mass index (BMI) with mortality in sepsis patients has not been clarified. We aimed to assess the influence hypoglycaemia at admission on mortality in sepsis patients according to BMI categories.Methods: This was a secondary analysis of a multicentre, prospective cohort study of 59 intensive care unit in Japan. The study included 1,184 patients (age ≥16 years) with severe sepsis; the diagnosis was made based on the Sepsis-2 criteria. After excluding patients with missing data of glucose level, BMI, or survival at discharge, patients were divided into groups according to the initial blood glucose level, <70 (hypoglycaemia) or ≥70 (non-hypoglycaemia) mg/dL, and according to BMI categories, <18.5 (low), 18.5–24.9 (normal), and ≥25 (high) kg/m2. The main outcome measure was in-hospital mortality. A multivariate logistic regression model was used to examine the association between hypoglycaemia and in-hospital mortality. BMI category-by-hypoglycaemia interactions were evaluated to assess the heterogeneity of the impact of hypoglycaemia on in-hospital mortality across BMI categories.Results: In total, 1,103 patients, including 65 patients with hypoglycaemia, were analysed. Among patients with hypoglycaemia, 13 had low, 38 had normal, and 14 had high BMI. Patients with hypoglycaemia showed higher in-hospital mortality (18/38, 47.4%) than those without hypoglycaemia (119/584, 20.4%) in the normal BMI group but not in the low and high BMI groups. In the multivariate logistic regression model, hypoglycaemia was not significantly associated with higher mortality in all patients (odds ratio [OR] 1.41; 95% confidence interval [CI] 0.77–2.58). However, there was a significant interaction between patients with normal BMI and hypoglycaemia on in-hospital mortality but not between patients with low or high BMI and hypoglycaemia (OR 2.32, 95% CI 1.05–5.07), and p for interaction: 0.0476).Conclusions: Hypoglycaemia at admission in sepsis patients was associated with high mortality in patients with normal BMI, but not in those with low or high BMI. This association may be used as a prognostic marker in sepsis patients.
Assessment of Non-progressive Dysarthria: Practice and Attitude of Speech and Language Therapists in Lebanon
Authors: Summaka Marwa , Harati Hayat , Hannoun Salem , Zein Hiba , Koubaisy Nour , Fares Youssef , Nasser Zeina 
Published: June 2021

Abstract
Background: Dysarthria is an acquired motor speech disorder. The evidence base for the assessment of dysarthria remains limited with professional practices relying mainly on therapists’ clinical experience. Limited information on the assessment practices of Lebanese speech and language therapists (SLTs) is available. Such information is crucial for the development of adequate therapy services for clients with non-progressive dysarthria. This study aims to explore the assessment practices and attitudes of Lebanese SLTs working with adults with non-progressive dysarthria and to investigate their adherence to the framework of the World Health Organization’s International Classification of Functioning, Disability and Health (ICF). Methods: A cross-sectional study was conducted in Lebanon between March and May 2021. Data was collected through an online survey that included information on socio-demographic characteristics, practices, and attitudes of SLTs who assess adults with non-progressive dysarthria. Results: A total of 50 Lebanese SLTs responded to the survey. The majority of SLTs (78%) assessed clients with non-progressive dysarthria across all ICF domains. SLTs reported dissatisfaction with the available assessment tools (64%) and reliance on informal tools (84%). In addition, 68% of the SLTs suggested the crucial need for the development of Arabic formal assessments that can quantitatively evaluate dysarthria and determine severity. The survey also showed that the respondents demonstrated a preference for the use of impairment-based tools.Conclusion: It can be concluded that the assessment practices of Lebanese SLTs, generally, follow the international trend and the recommended professional guidelines. Further research initiatives should be held to develop Arabic formal assessment tools for non-progressive dysarthria.
Thermal Computer Modeling of Laser Gyros at the Design Stage: A Promising Way to Improve Their Quality and Increase the Economic Efficiency of Their Development and Production
Authors: Kuznetsov Evgenii , Golyaev Yury , Kolbas Yury , Kofanov Yury , Kuznetsov Nikita , Vinokurov Yury , Soloveva Tatiana 
Published: June 2021

Abstract
In the paper, we consider the ways to improve the quality and economic efficiency of development and production of complex innovative electronic devices, among which are laser gyros (LGs). Development, manufacturing and testing of high-tech LG are relatively expensive. The accurate thermal modeling at the early stages of LG designing is an effective way to reduce overall costs owing to noticeable savings of expenses on multiple-laboratory tests of the LG under development and its re-design due to overheating. Use of the inexpensive Russian computer system ASONIKA for thermal modeling provides yet another boost to cost efficiency. In the paper, details of application of the electro-thermal analogy method, finite difference method, grid method, graph method in ASONIKA are described. The developed algorithm of creation of LG thermal model with the procedure of step-by-step disaggregation (zooming technique) is presented. The process of LG modeling by ASONIKA computer system is explained; the created LG thermal model in graphic view and the obtained thermal field of one of PCB in colored view are demonstrated. Electronic components prone to overheating are specified. The paper also presents the results of empirical verification of modeling with actual measurement of temperature by the thermal sensors installed in places corresponding to the model nodes; those measurements confirmed high accuracy of ASONIKA-based simulation.
Platelet-to-Lymphocyte ratio (PLR) is a Novel Independent Risk Factor for Newborn Patients in the Neonatal Intensive Care Unit (NICU)
Authors: Tang Yanfei , Teng Yiqun , Xu Lingyan , Xu Guangtao , Chen Deqing , Jin Xin , Li Wanlu , Jin Xiuhui , Zhu Wen , Hu Bo , Shen Ruilin , Zhu Yuzhang 
Published: June 2021

Abstract
Objective: To investigate the prognostic significance of the platelet-to-lymphocyte ratio (PLR) for newborn patients in the neonatal intensive care unit (NICU).Design: A retrospective cohort study.Setting and participants: Data on 5240 newborn patients in the NICU extracted from the Multiparameter Intelligent Monitoring in Intensive Care III (MIMIC III) database.Methods: Spearman correlation was used to analyze the association of PLR with length of hospital and ICU stays. The chi-square test was used to analyze the association of PLR with mortality rate. Multivariable logistic regression was used to determine whether the PLR was an independent prognostic factor of mortality. The area under the receiver operating characteristic (ROC) curve was used to assess the predictive ability of models combining PLR with other variables.Results: PLR was negatively associated with length of hospital stay and ICU stay (hospital stay: Spearman’s rho=-0.416, P<0.0001; ICU stay: Spearman’s rho=-0.442, P<0.0001). PLR was significantly correlated with hospital mortality (P<0.0001). Lower PLR was associated with higher hospital mortality (OR=0.85, 95% CI=0.75-0.95, P=0.005) and 90-day mortality (OR=0.85, 95% CI=0.76-0.96, P=0.010). The prognostic predictive ability of models combining PLR with other variables for hospital mortality was moderately good (AUC for Model 1=0.804; AUC for Model 2=0.964).Conclusion: PLR is a novel independent risk factor for newborn patients in the NICU.
Vitamin D3 and calcium carbonate supplementation for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology (VITALITY Trial): study protocol for a randomised placebo-controlled trial
Authors: Dzavakwa Nyasha Veronica , Chisenga Molly , McHugh Grace , Filteau Suzanne , Gregson Celia Louise , Kasonka Lackson , Kranzer Katharina , Banda-Mabuda Hildah , Mujuru Hilda , Redzo Nicol , Rowland-Jones Sarah , Schaible Ulrich E. , Simms Victoria , Ferrand Rashida Abbas 
Published: June 2021

Abstract
Background: Of the 2 million children living with HIV globally, 90% live in sub-Saharan Africa. Despite antiretroviral therapy, longstanding HIV infection is associated with several chronic complications in children including growth failure, particularly stunting and delayed puberty. Vitamin D deficiency, which is highly prevalent among children living with HIV in sub-Saharan Africa, has further adverse impact on bone health. This trial aims to establish whether supplementation with vitamin D 3 and calcium carbonate improves musculoskeletal health among peripubertal children living with HIV. Methods/design: We will conduct an individually randomised, double-blinded, placebo-controlled trial of weekly high-dose vitamin D 3 (20000iu) plus daily calcium carbonate (500mg) supplementation for 48 weeks. 840 children living with HIV aged 11-19 years taking ART for ≥6 months will be enrolled and followed up for 96 weeks. The primary outcome is total body less-head bone mineral content for lean mass adjusted for height (TBLH-BMC LBM ) Z-score at 48 weeks, measured by dual-energy x-ray absorptiometry (DEXA). Secondary outcomes are DEXA-measured Lumbar Spine Bone Mineral Apparent Density Z-score, number of respiratory infections, lean muscle mass and grip-strength at 48 and 96 weeks, and TBLH-BMC LBM Z-scores at 96 weeks. Sub studies will investigate the effect of the intervention on vitamin D 3 pathway metabolites and markers of bone turnover, intestinal microbiota, and innate and acquired immune function. Discussion: This is the largest trial to date of vitamin D supplementation in children living with HIV. Intervening to address deficits in bone accrual through childhood is critical for optimising adolescent and early adult bone health, and prevention of later adult osteoporotic fractures. Trial results will draw attention to the need to screen for and treat long-term comorbidities in children living with HIV in resource-limited settings.Trial registration: Pan African Clinical Trials Registry ID: PACTR20200989766029. Date ofregistration: 3 September 2020. URL of trial registry record: https://pactr.samrc.ac.za
Effect of Insemination Time on Pregnancy Rate and Ovulatory Events of Nili Ravi Buffalo Heifers in 7 Day CIDR Co-Synch
Authors: Haider Sajjad , Chishti Ghazanfar Ali , Mehmood Muhammad Usman , Jamal Muhammad Ameen , Mehmood Khalid , Shahzad Muhammad , Tahir Muhammad Zahid 
Published: June 2021

Abstract
The present study aimed to compare the pregnancy rates at the optimal time of artificial insemination in a 7-day CIDR Co-synch in Nili Ravi buffalo heifers. Forty Nili Ravi buffalo heifers were randomly separated into two treatments based on artificial insemination (A.I.) timing (72 vs 84 hours). All heifers were subjected to controlled internal drug release (CIDR), containing 1.38 grams of progesterone for 7 days. On CIDR removal, both treatments received 150 µg of prostaglandin intramuscularly. In 7-day CIDR Co-synch (n = 20), animals were injected 100 µg of GnRH intramuscularly and inseminated concurrently at 72 hours after CIDRs removal. The remaining half (n=20) were injected and inseminated concurrently at 84 hours of CIDRs removal. Pregnancy diagnosis was performed after 40 days of timed artificial insemination (TAI). The follicular growth rate in 7-day CIDR Co-synch was more significant at 84 than 72 hours. The interval from GnRH/A.I. to ovulation in 7-day CIDR Co-synch was significantly (P < 0.05) differ between 72 and 84 hours. Pregnancy rates were considerably higher in buffalo heifers inseminated at 84 hours (65%) than 72 hours (25%) in 7-day CIDR Co-synch treatment. In conclusion, the buffalo heifers treated with CIDR Co-synch based protocols in relation to TAI at 84 hours improves follicular growth rate, interval from GnRH/A.I. to ovulation, and pregnancy rate.
Descriptive Analysis of Reported Adverse Events Associated with Antiobesity Medications Using FDA Adverse Event Reporting System (FAERS) Databases 2013-2020
Authors: Alsuhibani Abdulrahman , Alrasheed Marwan , Gari Musaab , Hincapie Ana , Guo Jianfei 
Published: June 2021

Abstract
Background

Obesity is a globally growing health problem, and its treatment has been challenging. The usage of antiobesity medications (AOMs) has been associated with severe adverse events (AEs). Spontaneous reports of AOMs can present detailed information about AEs occurring after the time of marketing. Several AOMs have been withdrawn from the market owing to documented AEs.
Objective

To estimate and characterize the frequency of AEs attributable to the use of the AOMs between January 2013 and June 2020.
Setting:

US FDA Adverse Event Reporting System (FAERS) between January 01, 2013, and June 31, 2020,
Methods

A retrospective, descriptive analysis was conducted to analyze all major reported AEs including death, life-threatening, hospitalization, disability, and required intervention or congenital anomaly related to AOMs. The total numbers of AEs reports, cases, adverse reactions and outcomes were calculated for each medication, and patients' mean age and gender were reported.
Results

We found a total of 18,675 unique AEs reports associated with AOMs used for 15,143 patients. The mean age was 49.8 years [SD 1.83], while most patients were female adults (73.4 %). The main AEs of the safety reports were nausea, headache, cardiovascular diseases, dizziness, drug ineffectiveness, acute kidney failure/ kidney injury, and dry mouth. The FAERS database had 21,229 unique outcomes involving AOMs use, including 1,039 deaths (fatality ratio of 4.9% of all analyzed reports), 1,613 (7.6%) life-threatening events, 7,426 (35%) hospitalizations, and 1,249 (5.9%) disability cases. Phentermine/topiramate fatal cases represent 6% of the overall medication's reported AEs. The cardiovascular AEs were 542 reports (31%) for phentermine, 402 reports (23%) for liraglutide, 381 reports (22%) for phentermine/topiramate.
Conclusion

Although several AOMs have been withdrawn from the market and replaced with new ones, the utilization of the AOMs is widespread; the FAERS database's analysis revealed many serious AEs in the type of cardiovascular diseases and kidney complications attributable to the use of the AOMs. Therefore, it is necessary to continue and systematically monitor AOMs' safety to help optimize their use.
The association between the health-related physical fitness and inhibitory control in preschool children
Authors: Li Yiyan , Zhou Tang , Sang Menghao , Lu Yanhua , Liu Jiajia , He Xiaolong , Quan Minghui 
Published: June 2021

Abstract
Background
Inhibitory control develops rapidly during the preschool stage, and development of inhibitory control in this period is significant for the healthy growth of the future. However, most studies paid more attention to children and adolescents in recent years, but less focus on preschool children. Therefore, the purpose of this study was to explore the association between the health-related physical fitness and inhibitory control in preschool children.
Methods
This study was a cross-sectional study, 128 preschool children in Yangpu District of Shanghai were recruited by convenient sampling. The health-related physical fitness T-score (HPFT) was obtained by adding standard scores of six indicators: body mass index, handgrip strength, standing long jump, one-leg balance, 2×10m shuttle run test, and 20m shuttle run test. Inhibitory control was assessed using the flanker task and reflected by reaction time and accuracy.
Results
A total of 120 preschoolers were included in the final statistical analysis. After adjusting the confounders, HPFT was associated with reaction time (β=-2.49ms, 95%CI: -4.22, -0.75). Similarly, a negative association was observed between one-leg balance and reaction time (β=-12.04ms, 95%CI: -18.94, -5.15), and between 20m shuttle run and reaction time (β=-23.28ms, 95%CI: -37.00, -9.56). Compared with the participants in the lowest tertile, HPFT (β=-158.74, 95%CI: -309.63, -7.84), one-leg balance(β=-267.25ms, 95%CI: -420.71, -113.79) and 20m shuttle run (β=-215.58ms, 95%CI: -374.67, -56.49) were all negatively associated with reaction time of those in the highest tertile.
Conclusion
In addition, there was a non-linear relationship between HPFT and reaction time (β=-3.46ms,95%CI: -5.39, -1.53) when HPFT > 249. In conclusion, in order to improve the inhibitory control, it’s suggested that HPFT of preschoolers should be at least 249.
Distribution and Diversity of Macrophytes in Relation to Some Physico-Chemical Factors in the Ketar River, Ziway Catchment, Ethiopia
Authors: Chibsa Yadesa , Mengistou Seyoum , Kifle Demeke 
Published: June 2021

Abstract
Distribution and diversity of macrophytes in relation to some physico-chemical factors in the Ketar River were studied from December, 2017 to November, 2018. Physico-chemical parameters and macrophytes were collected from three stations along the river for eight months. Onsite measurements and laboratory work of physico-chemical was analyzed as recommended by APHA [31]. Macrophytes were collected manually using belt transect method. Except for pH and surface water temperatures, all the physico-chemical parameters measured showed no significant difference spatially. During the study period, sixteen macrophyte species belonged to fourteen families were identified. Among the identified macrophyte, 11 of them were emergent, while 3 were rooted with floating leaves and 2 free-floating. Free-floating macrophytes were shared the highest abundance followed by emergent. This research observed that the site (site 3) that was exposed to minimal human impact was rich in diversity and abundance of macrophytes. All the sites were dominated by emergent macrophytes that attained the highest relative frequency followed by rooted emergent species. Azolla nilotica and Pistia stratiotes were shared the highest abundance and were the dominant macrophyte with the relative frequency of 7.24% and density of 40.91%, and 7.93% and 26.54%, respectively. Under a favorable environment, nutrient loading from nearby creates more favorable conditions for the infestation of the invasive species (A. nilotica and P. stratiotes) to flourish and out-compete the other species of macrophyte. Therefore, anthropogenic activities that enhance nutrient addition to the River should be regulated.
Prevalence and risk factors of mental disorders during the COVID-19 pandemic in Bangladesh: a systematic review
Authors: Hosen Ismail , Mamun Firoj al , Mamun Mohammed A. 
Published: June 2021

Abstract
Background

The newly incepted Coronavirus Disease 2019 (COVID-19) has become a global public health threat, subsequently impacting individuals’ psychological wellbeing along with the risk of physical complications. Under the circumstance, it is essential to synthesize the existing evidence on psychological consequences regarding potential implications for policymaking and practice. Thus, a systematic attempt was compiled to review the Bangladeshi literature related to common mental health problems (i.e., depression, anxiety and stress) conducted during the COVID-19 pandemic.
Methods

Adhering to the PRISMA guideline, a systematic literature search was performed using Scopus, Medline or PubMed, Google Scholar, ResearchGate and Google, between 20 December 2020 and 5 March 2021, followed by predetermined eligibility criteria. The inclusion criteria for this review were observational studies concerning at least one common mental disorder (i.e., stress, depression and anxiety) prevalence and risk factors reported after the inception of the COVID-19 pandemic in Bangladesh and being published in peer-reviewed journals or preprint servers in the English language. A total of 24 preprint and peer-reviewed articles were finally recruited after meeting the inclusion criteria.
Results

Out of 24 studies, utmost of the investigation was directed among the general population (n = 9), followed by diverse cohorts such as students (n = 7), healthcare professionals (n = 4), COVID-19 infected individuals (n = 1), quarantined individuals (n = 1), wage-earners (n = 1), and bankers (n = 1). However, the prevalence range of anxiety (10.6–81.8%), depression (12.1–82.4%), and stress (11.1–85.6%) were found among altogether available literature during the COVID-19 pandemic in Bangladesh. Moreover, the associated risk factors of mental disorders included gender, age, residence area, family size, monthly family income, educational status, marital status, physical exercise, smoking, alcohol use, personal protective equipment, fear of COVID-19, presence of chronic illness, being unemployed and exposure of COVID-19 related news and social media.
Conclusions

This systematic review provides baseline data on mental disorders across various Bangladeshi cohorts, which are anticipated to be helpful to the respective authorities of the country implement cohort-specific mental health strategies.