bluuebunny/crossref_metadata_2025_split huggingface dataset:
Malignant tumors in children with neurofibromatosis Type 1
Authors: Mikhailova Svetlana , Kozlova Valentina , Kazubskay Tatiana , Sharapova Elena , Iurchenko Mariia , Khestanov Denis , Trofimov Evgenii , Mekheda Larisa 
Published: July 2021

Neurofibromatosis type I (NF1) is the monogenic inherited syndrome with established variability of clinical manifestations and the predisposition to the development of malignant tumors. Studying NF1 association with different types of cancers in children is necessary to understand the risk of their occurrence and the prognosis of the disease as well as subsequent studies of this predisposition.
Aim. Analysis the clinical data of patients with NF1 and malignant and benign tumors arisen in them.
Methods. A retrospective analysis of clinical data of 19 patients from 0 to 18 years old with a malignant tumor, carried out in N.N. Blokhin NMRCO from 1997 to 2018.
Results. The clinical signs of NF1 showed an age-dependent timing of their onset. Embryonal tumors were the most common and occurred in 11 out of 19 patients (57.9%), embryonal rhabdomyosarcoma predominated (42.1%), more often affecting the urogenital tract. Familial NF1 was found in 31.6% of patients. NF1 disease of the parents of these children (in four mothers and two fathers) was limited to pigmented skin lesions and multiple neurofibromas. Genetic testing of NF1 gene in three families of children with embryonal tumors revealed 2 de novo mutations — p.V2635FS & p.W1314X and one inherited from father to son (p.2363_2365del). Malignant peripheral nerve sheath tumors developed in 15.8% of patients by puberty. Soft tissue sarcomas and hematopoietic tumors occurred in 10.5% of patients, respectively. Melanoma was found in one patient (5.3%).
Conclusion. The data obtained make it possible to supplement the diapason of types of malignant tumors in children associated with NF1 and the possibility of their use in clinical practice for a more rational and targeted observation for patients. Further study of the molecular genetics and clinical aspects of NF1 is necessary for the development of promising therapies for NF1.
How far can I reach? The perception of upper body action capabilities in Parkinson’s disease
Authors: Readman Megan Rose , McLatchie Neil M. , Poliakoff Ellen , Crawford Trevor J. , Linkenauger Sally A. 
Published: July 2021

AbstractSuccessful interaction within the environment is contingent upon one’s ability to accurately perceive the extent over which they can successfully perform actions, known as action boundaries. Healthy young adults are accurate in estimating their action boundaries and can flexibly update them to accommodate stable changes in their action capabilities. However, there are conditions in which motor abilities are subject to variability over time such as in Parkinson’s disease (PD). PD impairs the ability to perform actions and can lead to variability in perceptual-motor experience, but the effect on the perceptions of their action boundaries remains unknown. This study investigated the influence of altered perceptual-motor experience during PD, on the perceptions of action boundaries for reaching, grasping, and aperture passing. Thirty participants with mild-to-moderate idiopathic PD and 26 healthy older adults provided estimates of their reaching, grasping, and aperture-passing ability. Participants’ estimates were compared with their actual capabilities. There was no evidence that individuals with PD’s perceptions were less accurate than those of healthy controls. Furthermore, there was some evidence for more conservative estimates than seen in young healthy adults in reaching (both groups) and aperture passing (PD group). This suggests that the ability to judge action capabilities is preserved in mild to moderate PD.
Evaluasi Tingkat Kebugaran Jasmani Mahasiswa pada Perkuliahan Pendidikan Jasmani IAIN Salatiga
Authors: Rozi Fatkhur , Safitri Setiorini Rahma , Syukriadi Amanda 
Published: July 2021

Tujuan penelitian ini adalah mengevaluasi tingkat kebugaran jasmani mahasiswa IAIN Salatiga setelah mengikuti perkuliahan pendidikan jasmani pada Semester Gasal 2020/2021. Metode penelitian ini adalah penelitian kuantitatif deskriptif dengan pendekatan survey. Hasil penelitian ini menunjukkan bahwa tingkat kebugaran jasmani mahasiswa laki-laki dengan kategori baik sebanyak 5 orang (33.3%), kategori sedang sebanyak 9 orang (60%), dan kategori kurang sebanyak 1 orang (6.7%). Adapun mahasiswa perempuan dengan kategori baik sebanyak 25 orang (25.3%), kategori sedang sebanyak 72 orang (72.7%), dan kategori kurang sebanyak 2 orang (2%). Simpulan penelitian ini adalah mahasiswa IAIN Salatiga yang mengikuti perkuliahan pendidikan jasmani secara umum memiliki tingkat kebugaran jasmani baik (26.4%), sedangkan lainnya berada pada kategori sedang (71%) dan kategori kurang (2.6%). Saran dalam penelitian ini adalah Mahasiswa IAIN Salatiga selalu menjaga kebugaran jasmani pada kategori baik dan bagi peneliti selanjutnya dapat meneliti faktor yang mempengaruhi kebugaran Mahasiswa IAIN Salatiga
Elemental Abundances in M31: Gradients in the Giant Stellar Stream*
Authors: Escala Ivanna , Gilbert Karoline M. , Wojno Jennifer , Kirby Evan N. , Guhathakurta Puragra 
Published: July 2021

Abstract
We analyze existing measurements of [Fe/H] and [α/Fe] for individual red giant branch (RGB) stars in the Giant Stellar Stream (GSS) of M31 to determine whether spatial abundance gradients are present. These measurements were obtained from low- (R ∼ 3000) and moderate- (R ∼ 6000) resolution Keck/DEIMOS spectroscopy using spectral synthesis techniques as part of the Elemental Abundances in M31 survey. From a sample of 62 RGB stars spanning the GSS at 17, 22, and 33 projected kpc, we measure a [Fe/H] gradient of −0.018 ± 0.003 dex kpc−1 and negligible [α/Fe] gradient with M31-centric radius. We investigate GSS abundance patterns in the outer halo using additional [Fe/H] and [α/Fe] measurements for six RGB stars located along the stream at 45 and 58 projected kpc. These abundances provide tentative evidence that the trends in [Fe/H] and [α/Fe] beyond 40 kpc in the GSS are consistent with those within 33 kpc. We also compare the GSS abundances to 65 RGB stars located along the possibly related Southeast (SE) shelf substructure at 12 and 18 projected kpc. The abundances of the GSS and SE shelf are consistent, supporting a common origin hypothesis, although this interpretation may be complicated by the presence of [Fe/H] gradients in the GSS. We discuss the abundance patterns in the context of photometric studies from the literature and explore implications for the properties of the GSS progenitor, suggesting that the high 〈[α/Fe]〉 of the GSS (+0.40 ± 0.05 dex) favors a major merger scenario for its formation.
SCExAO/MEC and CHARIS Discovery of a Low-mass, 6 au Separation Companion to HIP 109427 Using Stochastic Speckle Discrimination and High-contrast Spectroscopy*
Authors: Steiger Sarah , Currie Thayne , Brandt Timothy D. , Guyon Olivier , Kuzuhara Masayuki , Chilcote Jeffrey , Groff Tyler D. , Lozi Julien , Walter Alexander B. , Fruitwala Neelay , Bailey, III John I. , Zobrist Nicholas , Swimmer Noah , Lipartito Isabel , Smith Jennifer Pearl , Bockstiegel Clint , Meeker Seth R. , Coiffard Gregoire , Dodkins Rupert , Szypryt Paul , Davis Kristina K. , Daal Miguel , Bumble Bruce , Vievard Sebastien , Sahoo Ananya , Deo Vincent , Jovanovic Nemanja , Martinache Frantz , Doppmann Greg , Tamura Motohide , Kasdin N. Jeremy , Mazin Benjamin A. 
Published: July 2021

Abstract
We report the direct imaging discovery of a low-mass companion to the nearby accelerating A star, HIP 109427, with the Subaru Coronagraphic Extreme Adaptive Optics (SCExAO) instrument coupled with the Microwave Kinetic Inductance Detector Exoplanet Camera (MEC) and CHARIS integral field spectrograph. CHARIS data reduced with reference star point spread function (PSF) subtraction yield 1.1–2.4 μm spectra. MEC reveals the companion in Y and J band at a comparable signal-to-noise ratio using stochastic speckle discrimination, with no PSF subtraction techniques. Combined with complementary follow-up L
p photometry from Keck/NIRC2, the SCExAO data favors a spectral type, effective temperature, and luminosity of M4–M5.5, 3000–3200 K, and

log

10

(
L

/

L

⊙

)
=
−

2.28

−
0.04

+
0.04

, respectively. Relative astrometry of HIP 109427 B from SCExAO/CHARIS and Keck/NIRC2, and complementary Gaia–Hipparcos absolute astrometry of the primary favor a semimajor axis of 6.55+3.0
−0.48 au, an eccentricity of

0.54

−
0.15

+
0.28

, an inclination of

66.7

−
14

+
8.5

degrees, and a dynamical mass of

0.280

−
0.059

+
0.18

M
⊙. This work shows the potential for extreme AO systems to utilize speckle statistics in addition to widely used postprocessing methods to directly image faint companions to nearby stars near the telescope diffraction limit.
Local Active Galactic Nuclei with Large Broad-Hα Variability Reside in Red Galaxies
Authors: Liu Wen-Juan , Lira Paulina , Yao Su , Xu Dawei , Wang Jing , Dong Xiao-Bo , Martínez-Palomera Jorge 
Published: July 2021

Abstract
Inspired by our serendipitous discovery of six active galactic nuclei (AGNs) with varying broad-Hα fluxes over years from our search for intermediate-mass black holes (IMBHs), we conduct a systematic investigation of changing-look (CL) and large-variability AGNs. We collect all the CL AGNs at z < 0.15 and the reverberation-mapped AGNs with strongly variable broad Hα and perform careful decomposition fittings to both their images and spectra. We find two observational facts: (1) The host galaxies of local CL and large-variability AGNs, mainly being Seyferts, are in the red (gas-poor) tail of the general Seyfert galaxy population. (2) In contrast, there is a significant trend that their more luminous counterparts, namely CL and extremely variable quasars (CLQs and EVQs), are different: CLQs are generally in blue galaxies; in terms of the diagram of star formation rate and M
*, local CL Seyfert galaxies are located in the green valley, whereas CLQ hosts are in the star-forming main sequence. We propose explanations for those strongly variable Seyferts and quasars, respectively, under the assumption that accretion disks broadly depend on nuclear fueling modes. Local large-variability and CL Seyferts are in nuclear famine mode, where cold-gas clumps can be formed stochastically in the fueling flow, and their episodic infall produces sharp peaks in the accretion-rate curve. CLQs and EVQs are in feast fueling mode, which may account for both their preference for blue galaxies and their variability pattern (high-amplitude tail of the continuous distribution). Lastly, we propose a new thinking: to search for IMBHs by optical variability in red galaxies.
The Effect of a Strong Pressure Bump in the Sun’s Natal Disk: Terrestrial Planet Formation via Planetesimal Accretion Rather than Pebble Accretion
Authors: Izidoro André , Bitsch Bertram , Dasgupta Rajdeep 
Published: July 2021

Abstract
Mass-independent isotopic anomalies of carbonaceous and noncarbonaceous meteorites show a clear dichotomy suggesting an efficient separation of the inner and outer solar system. Observations show that ring-like structures in the distribution of millimeter-sized pebbles in protoplanetary disks are common. These structures are often associated with drifting pebbles being trapped by local pressure maxima in the gas disk. Similar structures may also have existed in the Sun’s natal disk, which could naturally explain the meteorite/planetary isotopic dichotomy. Here, we test the effects of a strong pressure bump in the outer disk (e.g., ∼5 au) on the formation of the inner solar system. We model dust coagulation and evolution, planetesimal formation, as well as embryo growth via planetesimal and pebble accretion. Our results show that terrestrial embryos formed via planetesimal accretion rather than pebble accretion. In our model, the radial drift of pebbles fosters planetesimal formation. However, once a pressure bump forms, pebbles in the inner disk are lost via drift before they can be efficiently accreted by embryos growing at ⪆1 au. Embryos inside ∼0.5–1.0 au grow relatively faster and can accrete pebbles more efficiently. However, these same embryos grow to larger masses so they should migrate inwards substantially, which is inconsistent with the current solar system. Therefore, terrestrial planets most likely accreted from giant impacts of Moon to roughly Mars-mass planetary embryos formed around ⪆1.0 au. Finally, our simulations produce a steep radial mass distribution of planetesimals in the terrestrial region, which is qualitatively aligned with formation models suggesting that the asteroid belt was born low mass.
The Intrinsic Properties of Multiwavelength Energy Spectra for Fermi Teraelectronvolt Blazars
Authors: Zhou R. X. , Zheng Y. G. , Zhu K. R. , Kang S. J. 
Published: July 2021

Abstract
In this paper, we have selected a sample of 64 teraelectronvolt blazars, with redshift, from those classified in the fourth Fermi Large Area Telescope source catalog.
3

3

https://fermi.gsfc.nasa.gov/ssc/data/access/lat/8yr_catalog/

We have obtained the values of the relevant physical parameters by performing a log-parabolic fitting of the average-state multiwavelength spectral energy distributions. We estimate the range of the radiation zone parameters, such as the Doppler factor (D), the magnetic field strength (B), the radiative zone radius (R), and the peak Lorentz factor (γ
p) of nonthermal electrons. Here, we show that (1) there is a strong linear positive correlation between the intrinsic synchrotron peak frequency and the intrinsic inverse Compton scattering (ICs) peak frequency among different types of blazars; (2) if radio bands are excluded, the spectral index of each band is negatively correlated with the intrinsic peak frequency; (3) there is a strong linear negative correlation between the curvature at the peak and the intrinsic peak frequency of the synchrotron bump, and a weak positive correlation between the curvature at the peak and the intrinsic peak frequency of the ICs bump; (4) there is a strong linear positive correlation between the intrinsic ICs peak luminosity and intrinsic γ-ray luminosity and between the intrinsic ICs peak frequency and peak Lorentz factor; (5) there is a strong negative linear correlation between

log

B

and

log

γ
p

; and (6) there is no correlation between

log

R

and

log

γ
p

.
Search for Gravitational Waves from the Coalescence of Subsolar Mass and Eccentric Compact Binaries
Authors: Nitz Alexander H. , Wang 王一 Yi-Fan 帆 
Published: July 2021

Abstract
We present a search for gravitational waves from subsolar mass compact-binary mergers that allows for nonnegligible orbital eccentricity. Subsolar mass black holes are a signature of primordial origin black holes, which may be a component of dark matter. To produce binary coalescences, primordial black holes may form close binaries either in the early universe or more recently through dynamical interactions. A signature of dynamical formation would be the observation of noncircularized orbits. We search for black hole mergers where the primary mass is 0.1–7M
⊙ and the secondary mass is 0.1–1M
⊙. We allow for eccentricity up to ∼0.3 at a dominant-mode gravitational-wave frequency of 10 Hz for binaries with component masses >0.5M
⊙. We find no convincing candidates in the public LIGO data from 2015–2017. The two most promising candidates have a false alarm rate of 1 per 3 and 4 yr, respectively, which combined is only a ∼2.4σ deviation from the expected Poisson rate. Given the marginal statistical significance, we place upper limits on the rate of subsolar mass mergers under the assumption of a null observation and compare how these limits may inform the possible dark matter contribution.
Pediatric Observational Priority Score and Early Warning Scoring System to Predict Admission Status in Pediatric Patients in Haji Adam Malik General Hospital
Authors: Wati Linda , Malisie Ririe Fachrina , Harahap Juliandi 
Published: July 2021

Background: Doctors must be able to quickly and accurately assess clinical condition of patients, especially in the emergency rooms. An easy scoring system but producing meaningful clinical conclusions is the reason for creating various scoring systems. Includes a scoring system for predicting the admission status of patients.
Aim: To determine the diagnostic value of POPS and EWSS to predicting admission status of pediatric patients in the emergency department.
Methods: Diagnostic tests for POPS and EWSS were done to predict the admission status of pediatric patients in the emergency department of Haji Adam Malik general hospital from May to October 2020. Subjects aged 1 month to 18 years were excluded if they left the emergency department prior to assessment, had trauma cases, died, inpatients due to social indications, and patients who came only to continue therapy were also excluded. POPS and EWSS assessments were carried out by the researcher and the admission status of the patients were determined by the doctor in charge in the emergency department.
Results: There were 119 children meeting the inclusion and exclusion criteria. POPS score ≥3 had sensitivity 82.65%, specificity 85.71%, and AUC 0.88 (p <0.001). EWSS score ≥2 had sensitivity 83.67%, specificity 71.43%, and AUC 0.83 (p <0.001).
Conclusion: POPS and EWSS had good diagnostic values in predicting the admission status of pediatric patients in the emergency department. POPS has a slightly higher diagnostic value than EWSS.
Pourquoi nous devons inscrire Facebook à la liste des Héritages de l’Unesco
Authors: Villarubias Marc 
Published: July 2021

Formidable photographie de la société humaine du début du xxi e siècle, les milliards de données collectées par Facebook doivent devenir un bien commun et être protégées par leur inscription à l’Unesco. Audacieuse et semée d’embûches, cette démarche est loin d’être utopique. Marc Villarubias , son initiateur, a choisi NECTART pour la révéler et exposer sa faisabilité.
La culture passe-t-elle enfin au vert ?
Authors: Delotte François 
Published: July 2021

Longtemps à la traîne sur le respect de l’environnement, le monde culturel a-t-il lui aussi basculé vers des pratiques « éco-responsables » ? François Delotte souligne les avancées mais aussi la nécessaire réflexion à mener sur l’évolution de pratiques moins énergivores.
Travailler pour être payé ? Origines et formes de la rémunération du travail
Authors: Clerc Marion , Labrue Lorine 
Published: July 2021

Cet encadré explore le lien entre rémunération et travail : le travail a-t-il toujours été rémunéré ? Quels sont les origines anthropologiques et les fondements microéconomiques de la rémunération du travail ? Comment s’articulent rémunération matérielle et reconnaissance sociale ?
Rémunérer le travail au Moyen Âge
Authors: Rivière François 
Published: July 2021

Entre le v e et le xii e siècle, la rémunération marchande du travail s’efface devant les relations de dépendance. Mais à partir du xiii e siècle, des marchés du travail se développent avec des contrats diversifiés et personnalisés, notamment dans les industries médiévales ou dans l’agriculture intensive, tandis que les rétributions de la noblesse et du clergé se distinguent par leurs composantes symboliques. Les autorités régulent les conflits et les fluctuations conjoncturelles, mais les privilèges des organisations de métiers et l’action des institutions n’abolissent pas la concurrence.
« Faire » son salaire : rémunérations variables et remontée de l’incertitude
Authors: Bernard Sophie 
Published: July 2021

On observe à partir des années 2000 un mouvement de diversification et de complexification des rémunérations. Si les managers usent des rémunérations variables comme d’un outil de mobilisation du personnel, les enquêtes démontrent qu’elles participent d’une remontée de l’incertitude au cœur du salariat stable et s’accompagnent d’un accroissement des inégalités de genre.
Productivité marginale du travail : entre théories, outils et idéologies
Authors: Askenazy Philippe 
Published: July 2021

La notion de productivité marginale des facteurs de production — y compris du travail — joue un rôle majeur dans la pensée économique contemporaine et la formation des économistes. Pour preuve, elle est enseignée en France dès le lycée à des jeunes en spécialité Sciences économiques et sociales (SES), alors même que beaucoup n’auront pas eu de cours de mathématiques leur introduisant la notion de dérivée ou de tangente ! Les analyses sur cette notion en elle-même abondent. Une revue exhaustive nécessiterait un ouvrage, je me contenterai donc ici de présenter une sélection personnelle.
Salaires et exploitation chez Marx
Authors: Subtil Hugo 
Published: July 2021

Cet encadré revient sur la définition de la rémunération des salariés que propose Karl Marx dans ses écrits. Il met en lumière les tensions qui sont sous-jacentes à cette définition notamment l’exploitation des travailleurs : ceux-ci ne touchent pas l’entièreté de la valeur qu’ils ont contribué à produire. Ainsi, selon Marx, le salaire ne représente pas la valeur du produit du travail mais la location de la force de travail .
Le salaire minimum en perspective historique
Authors: Gautié Jérôme , Oudot Julie , Subtil Hugo 
Published: July 2021

Le débat sur l’opportunité d’un salaire minimum (SM) est né à la fin du xix e siècle. Il renvoie à différents principes d’équité : le salaire de subsistance, la juste rémunération du travail (et son corollaire, l’absence d’exploitation), l’instrument de lutte contre les inégalités. Le SM n’est cependant pas toujours l’outil le plus adéquat pour lutter contre la pauvreté. La question sur l’opportunité d’une norme de SM au niveau européen est apparue récemment, et, au niveau national, la crise de la COVID renforce l’actualité du débat sur la juste rémunération des « premières de corvée ».
Rémunérer le travail des fonctionnaires
Authors: Rouban Luc 
Published: July 2021

La rémunération des fonctionnaires n’est pas comparable à celle des salariés du privé. Elle est fixée de manière unilatérale et ne peut pas faire l’objet de négociation avec les employeurs publics. Elle n’est pas liée à des prestations économiques mais à l’occupation d’un emploi dans une hiérarchie. La rémunération des fonctionnaires est donc déconnectée de leur investissement personnel dans un travail qui reste de nature collective. L’individualisation des rémunérations ne joue que sur une faible part de la rémunération totale. Si les théories du New Public Management ont cherché à introduire les logiques de rémunération du secteur privé dans la fonction publique, elles n’ont pas pu supprimer un rapport au travail dominé par le sens de l’utilité sociale et collective.
Réglementation sanitaire et environnementale des ONIEA
Authors: Commeau Natalie , Bodénez Philippe 
Published: July 2021

Nous pouvons être confrontés à des sources de bruit très variées durant la journée et la nuit : bruit de nos voisins, des entreprises, de loisirs, des transports… C’est pourquoi la réglementation encadrant la limitation de l’exposition au bruit est vaste. Plusieurs lois, décrets et arrêtés sont partiellement ou entièrement consacrés au bruit. Un texte reste fondateur : la loi n°92-1444 du 31 décembre 1992 relative à la lutte contre le bruit. La plupart de ses articles sont toujours en vigueur et codifiés dans le Code de l’environnement. Ce droit français a été complété par le droit européen. Enfin, l’encadrement juridique des nuisances sonores des aéronefs relève en grande partie du droit international. Les valeurs limites d’exposition du grand public aux ondes non ionisantes électromagnétiques (ONIE) actuellement en vigueur datent de 2002. La loi n°2015-136 du 9 février 2015, dite loi Abeille, traite de la sobriété, de la transparence, de l’information et de la concertation en matière d’exposition aux ONIE. L’ensemble de ces dispositions visent à limiter au mieux l’exposition de nos concitoyens à ces ondes, qui dans certains cas peuvent générer des désagréments plus ou moins importants.