bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of unicompartmental knee arthroplasty on lower extremity axis, tibiofemoral subluxation, and lateral knee joint distance
Authors: ASLAN Hakan , DUMAN Evrim , ATLI Osman Yağız , ÇEVİK Hüseyin Bilgehan 
Published: May 2021

Purpose: The aim of this study was to investigate the corrective effect of Oxford phase 3 medial unicompartmental knee arthroplasty (UKA) on the lower extremity axis, tibiofemoral subluxation and lateral joint distance.
Materials and Methods: The study included 105 knees that had undergone UKA. The Oxford Knee Score, EQ-5D-3LD and visual analog scale, and The Knee injury and Osteoarthritis Outcome Score were evaluated. Radiological evaluation was made of the lower extremity axis, tibiofemoral subluxation, and lateral knee joint distance.
Results: The postoperative mean improvement in the mechanical axis was 1.4° and in the tibiofemoral subluxation distance, 1.59 mm compared to preoperative values. The difference between the preoperative and postoperative lateral joint distance values was on average 0.25 mm lateral inner joint distance, 0.08 mm in the lateral middle joint distance and 0.34 mm in the outer joint distance. There was no significant difference in clinical results between the groups.
Conclusion: There were significant improvements in the postoperative period after cemented, cementless, and hybrid medial UKA in the measurements of lower extremity mechanical axis, tibiofemoral subluxation distance and lateral joint distances compared to the preoperative period.
Neuroprotective effects of phloretin and phloridzin on paclitaxel-induced neuronal damage in primary neuron cells
Authors: YAYLA Muhammed , ÜN Harun , BİNNETOĞLU Damla 
Published: May 2021

Purpose: Paclitaxel, is one of the most commonly used chemotherapeutic, causes neuron damage with some serious side effects such as neutropenia and peripheral neuropathy. In current study, we used phloretin and phloridzin to investigate their neuroprotective effects on paclitaxel-induced neuronal damage.
Materials and Methods: The neuroprotective effects of phloretin and phloridzin has been analyzed on cell culture of primary neuron cells and evaluated by testing cell viability, total oxidant and total antioxidant capacities and expression of caspase-3, caspase-9 and TNF-α. Paclitaxel administration caused cell death and significant increase of total oxidant levels and activation of apoptotic genes such as caspase-3, caspase-9 and TNF-α.
Results: Phloretin and phloridzin treatments at micromolar concentrations reduced paclitaxel-induced cell death by increasing total antioxidant levels. Also these two flavonoids protect neuron cells from apoptosis by decreasing caspase-3, caspase-9 and TNF-α gene expression. For this reason, these molecules may recover the oxidative damage, and restore normal cellular conditions.
Conclusion: This study shows the promising neuroprotective ability of the phloretin and phloridzin able to protect neuron cells from injury induced by paclitaxel, actively increasing antioxidant capacity, normalizing oxidant levels and consequently avoiding cell death.
Karitane Ebeveyn Kendine Güven Ölçeği: Türkçe geçerlik ve güvenirlik çalışması
Authors: YILMAZ Büşra , OSKAY Ümran 
Published: May 2021

Amaç: Bu çalışmanın amacı, 0-12 aylık bebeğe sahip ebeveynlerde kullanılmak üzere geliştirilmiş olan Karitane Ebeveyn Kendine Güven Ölçeği (KEKGÖ)’nin Türkçe uyarlamasının geçerliği ve güvenilirliğini test etmektir.
Gereç ve Yöntem: Çalışma verileri çevrimiçi platformda Nisan-Aralık 2020 tarih aralığında toplandı. Çalışmaya 0-12 aylık bebeği olan 218 ebeveyn dâhil edildi. Verilerin toplanmasında katılımcı tanıtım formu, Anne-Baba Stres Ölçeği ve KEKGÖ kullanıldı. Çalışmada KEKGÖ’yü Türk dili ve kültürüne uyarlamak, geçerlik ve güvenirliğini belirlemek için dil ve kapsam geçerliliği, madde analizi, açımlayıcı ve doğrulayıcı faktör analizleri, iç tutarlılık katsayıları, eş zamanlı ve yakınsak geçerlik sonuçları değerlendirildi.
Bulgular: Katılımcıların yaş ortalaması 30.19±4.10’dur. Ölçeğin toplam Kapsam Geçerlik İndeksi 0.98 olarak hesaplandı. Ölçeğin iki faktörlü yapısının kabul edilebilir uyum indeksleri aralığında olduğu bulundu. Bir maddenin çıkarılması ve birinin ters puanlanması sonrası 14 maddelik ölçeğin Cronbach alfa değeri, toplam ölçek için 0.934, “Bebeğin bakımı” alt boyutu için 0.966 ve “Ebeveynlik rolü” alt boyutu için 0.712 olarak belirlendi.
Sonuç: KEKGÖ’nün Türkçe versiyonunun 0-12 aylık bebekleri olan annelerin ebeveynlik konusundaki kendine güven durumlarının değerlendirilmesi için uygun olduğu bulunmuştur.
Gargling Effect of Zamzam Water on Salivary pH
Authors: Alawiyah Fadlun , Chairani Shanty , Anastasia Danica 
Published: May 2021

Caries is a multifactorial infection disease that happened during the decrease of salivary pH caused by acids from bacterial metabolism. Bicarbonate is an important buffer component in saliva that can help neutralize salivary pH. Zamzam water has high bicarbonate content. This study aimed to evaluate the effect of gargled with Zamzam water on salivary pH. This experimental research was done with pre-test and post-test control group design involving 40 dentistry students at the University of Sriwijaya aged 18-23 years old, with DMF-T score ≤3. Samples were divided into 2 groups, the Zamzam water group, and thedistilled water group. Samples gargled their mouth with 10 ml of a 25% sucrose solution for one minute, then saliva was collected with spitting method and salivary pH was measured with digital pH meter and recorded as initial pH. Samples then gargledwith 20 ml of Zamzam water or distilled water according to each group for one minute, then saliva was collected in the same way as before, and pH was measured and recorded as final pH. Data were analyzed with paired t-test and Mann-Whitney. The result showed that salivary pH increased significantly after gargled with Zamzam water (p0,05). The mean difference of salivary pH aftergargled with Zamzam water was statistically higher than distilled water (p0,05). In conclusion, Gargled with Zamzam water can increase salivary pH.
Política tecnológica e industrial en contexto semiperiférico: la producción pública de medicamentos en Argentina (2007-2015)
Authors: Zubeldía Lautaro , Hurtado Diego 
Published: May 2021

Nos enfocamos en los procesos de toma de decisiones vinculados al impulso de las políticas de producción pública de medicamentos (PPM) en Argentina, durante el período 2002-2015, como caso paradigmático de país semiperiférico que se propone construir capacidades estatales en un sector estratégico de la economía y del desarrollo social. Con este objetivo analizamos: (i) las iniciativas públicas para definir objetivos y construir capacidades de coordinación y organización del sector; (ii) las presiones políticas y económicas del sector privado y sus consecuencias; y (iii) la yuxtaposición de diferentes sentidos socioeconómicos asignados a las políticas de PPM. Concluimos que, como sector emergente, la PPM alcanzó dimensión de política pública y que, a pesar de obstáculos y contradicciones, al final del período estudiado logró un nivel de organización inédito. También inferimos que la trayectoria del sector de PPM ejemplifica un rasgo definitorio de los países semiperiféricos como aquellos que se proponen alterar los roles asignados por la división internacional del trabajo al presionar sobre la “zona de contacto” de algunos sectores de retornos crecientes reservados a las grandes firmas.
Todo fallo es político. Fragmentos de ecología política en la Suprema Corte de Justicia de Mendoza
Authors: Salomone Mariano Javier 
Published: May 2021

En 2015 la Suprema Corte de Justicia de Mendoza ratificó la constitucionalidad de la Ley 7722, que prohíbe el uso de sustancias tóxicas en la explotación de minería metalífera. En esta provincia el conflicto social alrededor de proyectos de minería en gran escala adquiere desde 2003 una especial relevancia histórica. El artículo propone un análisis de la hegemonía discursiva que construye el Estado a través de uno de sus brazos, el poder judicial. Para ello realiza una lectura crítica del fallo identificando las referencias principales que tejen su argumentación, organizan su sentido y lo vinculan a cierta ecología política, en tanto trama ideológica que sostiene y organiza una determinada racionalidad en la apropiación social de la naturaleza.
Elecciones y partidos en América latina en el cambio de ciclo
Authors: Sánchez Emilio 
Published: May 2021

Este libro es una compilación de textos que analizan elecciones presidenciales y legislativas en América Latina a partir de un conjunto similar de conceptos e indicadores que permiten realizar una comparación en comicios celebrados entre 2013 y el primer trimestres de 2017 en 17 países de la región.
Gestão democrática na Educação Infantil: desafios dos conselhos escolares
Authors: Cordeiro Priscila Da Silva , Nascimento Anelise Monteiro 
Published: May 2021

Esta pesquisa investiga a democratização da escola de Educação Infantil a partir do Conselho Escolar (CE). Os conceitos de referência são: gestão democrática (Paro 2007); política (Mouffe 2003; 2015) e poder (Foucault, 1995). As análise fundamentam-se o Ciclo de políticas (Ball; Mainardes, 2011). Para coleta da dados foram realizadas entrevistas (KRAMER, 2003) e análise das atas dos encontros de um CE. Conclui-se que os CE são uma prática recente, apesar do texto da política datar de 1996. As políticas que preconizam a gestão democrática têm buscado a descentralização do poder, que esbarra na hierarquia dos postos pré-fixados pela Secretaria de Educação para o CE, assim como na falta de uma formação que seja capaz de articular conhecimentos, dando suporte à atuação dos conselheiros.
Federalismo cooperativo, financiamento da educação e royalties do petróleo
Authors: Najjar Jorge Nassim Vieira , Vicente Debora Da Silva , Morgan Karine Vichiett 
Published: May 2021

RESUMO: Este artigo pretende analisar, tendo por consideração o pacto federativo construído na Constituição de 1988, a repartição constitucional de competências legislativas e materiais e os mecanismos de financiamento da educação, como se deu a evolução histórica do tratamento constitucional e legal acerca da propriedade do petróleo e gás natural no Brasil, quais os regimes jurídicos em vigor, as espécies de participações ou receitas governamentais devidas pela sua exploração, como tem se dado a disputa pela definição dos seus beneficiários, e quais são as regras que incidem sobre sua adequada aplicação pelos entes federados.Palavras-chave: Federalismo Cooperativo. Regime de Colaboração. Educação Básica. Financiamento. Royalties. COOPERATIVE FEDERALISM, EDUCATION FINANCING AND ROYALTIES OF OIL. ABSTRACT: This article aims to analyze, taking into consideration the federative pact built in the 1988 Constitution, the constitutional division of legislative and material competences and the financing mechanisms of education, as the historical evolution of the constitutional and legal treatment of oil and natural gas in Brazil, what are the legal regimes in force, the types of stakes or government revenues due for their exploitation, how has the dispute over the definition of their beneficiaries, and what rules apply to their proper application by the federated entities? Keywords: Cooperative Federalism. Collaboration Regime. Basic education. Financing. Royalties. FEDERALISMO COOPERATIVO, FINANCIACIÓN EDUCATIVAY REGALÍAS DE ACEITE. RESUMEN: Este artículo tiene como objetivo analizar, considerando el pacto federativo construido en la Constitución de 1988, la división constitucional de las competencias legislativas y materiales y los mecanismos de financiación de la educación, como la evolución histórica del tratamiento constitucional y legal sobre cuáles son los regímenes legales vigentes, los tipos de tenencias o ingresos del gobierno debido a su exploración, cómo ha surgido la disputa sobre la definición de sus beneficiarios y qué reglas se aplican a su correcta aplicación por entidades federadasPalabras clave: Federalismo cooperativo. Régimen de colaboración. Educación básica. Financiacion Regalías
Gênero e sexualidades no ensino médio: enfrentamentos e negociações
Authors: Vetorazo Francisca Helena Gonçalves , Sampaio Helena 
Published: May 2021

Focalizando o cotidiano de estudantes do ensino médio e a interação deles com colegas e representantes de outras gerações, o artigo discute o caráter normatizador da instituição escolar (e seus limites) no que diz respeito a questões de gênero e sexualidades. Constatando a presença hiperbólica dessas questões nas escolas de ensino medio, seguem duas considerações mutuamente implicadas: gênero e sexualidades são alvo de resistência de subjetividades por parte de todos que atuam no ambiente escolar; as escolas constituem espaço, por excelência, para o aprendizado do reconhecimento da igualdade de gênero e da diversidade sexual como direitos.
Isotope-Geochemical Evidence of the Nature of the Protoliths of Diamondiferous Rocks of the Kokchetav Subduction–Collision Zone (Northern Kazakhstan)
Authors: Shatsky V.S. , Ragozin A.L. , Skuzovatov S.Yu. , Kozmenko O.A. , Yagoutz E. 
Published: May 2021

Abstract
—The isotope-geochemical features of diamondiferous metamorphic rocks of the Kokchetav subduction–collision zone (KSCZ) show that both the basement rocks and the sediments of the Kokchetav massif were their protoliths. A whole-rock Sm–Nd isochron from the diamondiferous calc-silicate, garnet–pyroxene rocks and migmatized granite-gneisses of the western block of the KSCZ yielded an age of 1116 ± 14 Ma, while an age of 1.2–1.1 Ga was obtained by U–Pb dating of zircons from the granite-gneiss basement of the Kokchetav microcontinent. Based on these data, we assume that the protoliths of the calc-silicate, garnet–pyroxene rocks and the granite-gneisses of the KSCZ were the basement rocks sharing an initially single Nd source, which was not influenced by high- to ultrahigh-pressure metamorphism (~530 Ma). Therefore, their geochemical features are probably not directly related to ultrahigh-pressure metamorphism. The corresponding rock associations lack isotope-geochemical evidence of partial melting that would occur during ultrahigh-pressure metamorphism, which suggesting that they were metamorphosed under granulite-facies conditions. At the same time, the high-alumina diamondiferous rocks of the Barchi area (garnet–kyanite–mica schists and granofelses), which were depleted to different degrees in light rare-earth elements (REE) and K, have yielded a Sm–Nd whole-rock isochron age of 507 ± 10 Ma indicating partial melting of these rocks during their exhumation stage. The close ɛNd (1100) values of the basement rocks and garnet–kyanite–mica schist with geochemical characteristics arguing against its depletion during high-pressure metamorphism indicate that the basement rocks were a crustal source for high-alumina sediments.
Assessment of the Initial, Promising, and Predicted Geologic and Recoverable Oil Resources of the West Siberian Petroleum Province and Their Structure
Authors: Kontorovich A.E. , Livshits V.R. , Burshtein L.M. , Kurchikov A.R. 
Published: May 2021

Abstract
—The structure of the initial and predicted oil resources of the West Siberian petroleum province is quantitatively assessed. The assessment is based on the law of mass distribution of hydrocarbon accumulations, i.e., the truncated Pareto distribution and simulation modeling of the general set of oil fields. This approach makes it possible to estimate the amount of oil and the total oil resources concentrated in intervals of any size, in particular, in intervals of small and fine fields, in order to determine the economic efficiency of their development. The considered estimates do not apply to unconventional resources, such as the shale oil of the Bazhenov Formation.
Long-term impact of recombinant human erythropoietin on transfusion support in patients with chronic renal failure
Authors: Popovsky M. A. , Ransil B.J. 
Published: May 2021

Abstract
Published reports on the impact of recombinant human erythropoietin (r-HuEpo) on transfusion requirements of patients with chronic renal failure have been limited to small populations and relatively brief follow-up. In this study we reviewed the effects of this drug on 86 patients with well-characterized transfusion requirements, followed for 18 months at seven dialysis centers. The median red blood cell transfusion requirements per patient per year decreased from 14 in 1987 and 1988 to 11 in 1989, when r-HuEpo was licensed in the United States (p < .01) and fell to 2 in 1990 (p < .01). The proportion of patients who became transfusion-independent increased from 34 percent in 1989 to 69 percent in 1990 (p < .001). These data demonstrate that r-HuEpo significantly decreases transfusion requirements of patients with chronic renal disease.
Immunohematology
1996;12:1-3.
Effect of pronase on high-incidence blood group antigens and the prevalence of antibodies to pronase-treated erythrocytes
Authors: Reid M.E. , Green C.A. , Hoffer J. , Øyen R. 
Published: May 2021

Abstract
Pronase is a useful and relatively nonspecific protease that cleaves many red blood cell (RBC) membrane proteins that carry blood group antigens. Unexpected findings in tests using pronase-treated RBCs during the investigation of a patient’s blood sample led us to test which high-incidence blood group antigens were sensitive and which were resistant to pronase treatment, and to determine the prevalence of antipronase in the serum of blood donors. Our results show that antigens in the Cromer and Lutheran blood group systems and the JMH antigen were sensitive to pronase treatment of RBCs. Antigens in the Dombrock blood group system and Sc1 were either sensitive to or markedly weakened by pronase treatment of RBCs. The following high-incidence antigens were resistant to treatment of RBCs with pronase: AnWj, Ata, Coa, Co3, Dib, EnaFR, Era, Fy3, Jk3, Jra, k, Kpb, Jsb, K14, Lan, Oka, Rh17, U, Vel, and Wrb. Over half of the serum samples from normal blood donors contained antibodies to pronase-treated RBCs. When testing human serum against pronase-treated RBCs, it is essential either to use an autocontrol or to perform the testing with an eluate.
Liss-dependent autoantibody with apparent anti-U specificity
Authors: Chiofolo J.T. , Reid M.E. , Charles-Pierre D. 
Published: May 2021

Abstract
Nonspecific binding of gamma globulin and complement, resulting in falsely positive indirect antiglobulin tests, has occurred with use of low-ionic strength saline solution (USS) reagents. These LISS-dependent antibodies have not been described in association with any particular disease state, nor do they have any apparent clinical significance. We present a LISS-dependent antibody with apparent autoanti-U specificity.
Elimination of a requirement for Vel-negative red blood cells and successful transfusion following chromium-51 survival study
Authors: Davey R.J. , Procter J.L. 
Published: May 2021

Abstract
A 42-year-old woman presented with anemia and complex serologic test results that included a requirement for Vel-negative red blood cells (RBCs). Rare Vel-negative units were located and transfused, but her anemia worsened. As further serologic evaluation was inconclusive, an in vivo recovery study with Vel-positive RBCs was performed. Normal 24-hour recovery of these cells resulted in removal of the Vel-negative antigen restriction and successful transfusion of the patient. Resolution of the inconclusive anti-Vel serology with an in vivo recovery study simplified the acquisition of blood for this patient and conserved rate RBC units.
Immunohematology
1995;11:39–42.
Loss of the Knops blood group system antigens from stored blood
Authors: Moulds J.M. , Brown L.L. , Brukheimer E. 
Published: May 2021

Abstract
Complement receptor type one (CR1) is a polymorphic glycoprotein, present on red blood cells (RBCs), that carries the Knops blood group system antigens. Since Knops system antigens can vary in strength, we investigated whether CR1 deteriorated upon storage, thus affecting Knops blood group system antigen reactivity. Units of whole blood were collected in CPDA-1 and evaluated at day 0 and day 35 for antigen strength, using routine serologic techniques. CR1 was quantitated by an enzyme-linked immunoassay and by flow cytometry measurements. The CR1 expression polymorphism was ascertained by a Hind III restriction fragment length polymorphism analysis. RBC membrane proteins were separated by SDS-PAGE and analyzed for CR1 size by immunoblotting. During the 35-day study interval, no notable decrease was found in RBC-CR1 by flow cytometry. However, CR1 protein was shown to be lost by proteolytic cleavage, as well as by vesiculation. This CR1 protein loss may contribute to the variability of serologic reactions characteristic of the Knops blood group system antigens. Titration results showed a significant decrease in score between day 0 and day 35 using anti-McCa and anti-Yka. Anti-Kna and anti-Sla did not demonstrate statistically significant differences in titration scores.
Immunohematology
1995;11:46–50.
ABO discrepancy with monoclonal ABO reagents caused by a pH-dependent autoantibody
Authors: Kennedy M.S. , Waheed A. , Moore J. 
Published: May 2021

Abstract
ABO discrepancy was noted when a patient’s unwashed saline red cell suspension was tested with monoclonal ABO reagents. The discrepancy was resolved when a washed (× 3) saline red cell suspension was used in repeat testing. The patient’s serum contained an autoagglutinin that reacted optimally below pH 7.0. Tire discrepancy occurred when monoclonal ABO reagents, formulated at a low pH, lowered the pH of the reaction mixture, and autoagglutination was observed.
Immunohematology
1995;11:71–73.
Case report: solid-phase platelet crossmatching to support the alloimmunized patient
Authors: O’Connell B.A. 
Published: May 2021

Abstract
Platelet crossmatching by a solid-phase red cell adherence assay was used to provide compatible platelets for two alloimmunized patients with leukemia. In this study, a successful platelet transfusion was defined as giving a corrected count increment (CCI) of >7,500 in a posttransfusion sample. For patient A, a total of 205 random platelet concentrates (PCs) were crossmatched. Eleven were considered compatible. These 11 PCs were transfused during five transfusion episodes. Four of the five transfusions produced CCIs of >7,500 and were considered successful. Individually, eight of the eleven units were considered in vivo compatible, and five of the eight donors of these units agreed to become apheresis donors. Platelets from three of these five apheresis donors gave CCIs of >7,500. For patient B, 1,074 random PCs were crossmatched, and 332 were considered compatible. These units were administered during 78 different transfusions. Seventy-one of these transfusion episodes resulted in CCIs of >7,500. In addition, 19 apheresis donors were identified by platelet crossmatching, and they provided platelets for 38 of 39 successful transfusions for Patient B. Platelet crossmatching should therefore be considered when a blood bank is called upon to support a refractory thrombocytopenic patient.
Immunohematology
1995;11:150–152.