bluuebunny/crossref_metadata_2025_split huggingface dataset:
Explain the Experience of Family Caregivers Regarding Care of Alzheimer's Patients: A Qualitative Study
Authors: Ashrafizadeh Hadis , Gheibizadeh Mahin , Rassouli Maryam , Hajibabaee Fatemeh , Rostami Shahnaz 
Published: June 2021

Introduction: Due to the long-term and progressive nature of Alzheimer's disease, these patients need caregivers who will be responsible for their long-term care and who may then experience an increasing burden related to the progressive disease course, so it is important to understand the experiences of caregivers. The aim of this study was to explain the experience of family caregivers regarding care of Alzheimer's patients.Methods: The present qualitative study employed a conventional content analysis approach and was conducted in Iran in 2020. This research was done through in-depth and semi-structured interviews with 11 qualified caregivers enrolled in a purposive sampling method. Interviews continued until data saturation. Data analysis was performed simultaneously with data collection. Interviews were recorded, transcribed and analyzed through Graneheim and Lundman style content analysis and data management was done with MAXQDA software. In order to achieve the accuracy and validity of the study, the Four-Dimensions Criteria (FDC) by Lincoln and Guba, credibility, dependability, confirmability, and transformability were considered and used.Results: A total of 11 caregivers with mean age and standard deviation 48, ±26.12 participated in the study. The acquired data were put in two main categories of “burnout and exhaustion” with six subcategories and “excellence and personal growth” with three subcategories.Conclusion: In this study, we found that perceptions of caregivers' role were not the same among study participants, who experienced both positive and negative dimensions of care provision to AD patients. The care experience has a spectrum that, in some people, leads to positive outcomes such as growth. A major part of caregiver challenges is related to the burden of caregiving strain and the erosive nature of the disease. Therefore, health planners should identify the challenges, pain and suffering of caregivers and seek to address them through appropriate strategies.
Case Report: Psychopathological Syndromes in the Course of Lupus Erythematosus and the Co-occurrence of Lupus Erythematous With Mental Disorders
Authors: Stelmach Ewa , Masiak Jolanta 
Published: June 2021

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease that leads to a chronic inflammatory process in tissues and organs. The neuropsychiatric systemic lupus erythematosus (NPSLE) is a set of neuropsychiatric symptoms that derive from the central and peripheral nervous system and are observed in the course of SLE.Case Report and Final Diagnostic and Therapeutic Results: A diagnostic and therapeutic process in a patient with the signs and symptoms of SLE and bipolar disorder (BD) has been described. Bipolar disorder has been diagnosed as a primary disorder while SLE as a comorbid disease.Discussion: Common immunological mechanisms in BD and SLE are the reason for difficulties in diagnosing BD with co-occurring SLE. It should be determined whether BD is a primary disorder or a secondary component of a clinical picture of SLE (NPSLE) or whether mood and/or psychotic disorders are the result of steroid therapy in the course of SLE (steroid-induced mood and psychotic disorders, SIMPD).Conclusion and the Patient's Perspective: The presented case report is a unique description of a patient with a primary diagnosis of BD with comorbid SLE.
Wprowadzenie: Westlessness czyli zmierzch Zachodu 2.0?
Authors: Cianciara Agnieszka K. 
Published: June 2021

This article introduces the special section entitled Westlessness or the Decline of the West 2.0? Whereas the concept of the West remains a moving target and requires the Other – the Rest to exist and thrive, it does organize both global power relations and the way we think about them. Thus the ‘decline of the West’ is not only about material realities, but also about de-legitimizing practices and discourses produced by strategically-acting actors both outside and within the West itself. Whereas Westlessness in the World refers to the weakening ability of shaping the Rest, Westlessness in the West denotes contestation and hollowing-out of the liberal rules of the game in the very centre of the West: the us and the European Union. The question remains as to whether COVID-19 pandemic brings “more of the same”, while amplifying existing trends, or whether it provides for a transformation impulse and possibly Western revival.
La historia de Ixkik y la celebración del miércoles de Chilate en Rabinal, Guatemala
Authors: Mosquera Saravia María Teresa 
Published: June 2021

En esta ocasión se presenta una analogía entre la historia de Ixkik del Popol Vuh y la celebración del Miércoles de Chilate en Rabinal, que es un ritual que se celebra un día antes del jueves de Corpus Christi. Para éste análisis se parte de la relación entre; agricultura, religión y cosmovisión maya que se presenta en una primera parte, posteriormente se sintetiza la historia de Ixkik en el Popol Vuh, para proporcionar algunos de los elementos que se utilizarán en la segunda parte del manuscrito, ya que en esta se hace una etnografía de la celebración del miércoles de chilate y se analizan algunos de los elementos de la cosmovisión maya presentes en ella.
A Standardized Framework for Evaluating Surgical Enhanced Recovery Pathways: A Recommendations Statement from the TDABC in Health-care Consortium
Authors: Etges Ana Paula B.S. , Stefani Luciana Paula Cadore , Vrochides Dionisios , Nabi Junaid , Polanczyk Carisi Anne , Urman Richard D. 
Published: June 2021

Background: Innovative methodologies to redesign care delivery are being applied to increase value in health care, including the creation of enhanced recovery pathways (ERPs) for surgical patients. However, there is a lack of standardized methods to evaluate ERP implementation costs. Objectives: This Recommendations Statement aims to introduce a standardized framework to guide the economic evaluation of ERP care-design initiatives, using the Time-Driven Activity-Based Costing (TDABC) methodology. Methods: We provide recommendations on using the proposed framework to support the decision-making processes that incorporate ERPs. Since ERPs are usually composed of activities distributed throughout the patient care pathway, the framework can demonstrate how the TDABC may be a valuable method to evaluate the incremental costs of protocol implementation. Our recommendations are based on the review of available literature and expert opinions of the members of the TDABC in Healthcare Consortium. Results: The ERP framework, composed of 11 steps, was created describing how the techniques and methods can be applied to evaluate the economic impact of an ERP and guide health-care leaders to optimize the decision-making process of incorporating ERPs into health-care settings. Finally, six recommendations are introduced to demonstrate that using the suggested framework could increase value in ERP care-design initiatives by reducing variability in care delivery, educating multidisciplinary teams about value in health, and increasing transparency when managing surgical pathways. Conclusions: Our proposed standardized framework can guide decisions and support measuring improvements in value achieved by incorporating the perioperative redesign protocols.
Climatic variables and ecological modelling data for birds, amphibians and reptiles in the Transboundary Biosphere Reserve of Meseta Ibérica (Portugal-Spain)
Authors: Campos João , Rodrigues Sara , Freitas Teresa , Santos João , Honrado João , Regos Adrián 
Published: June 2021

Climate change has been widely accepted as one of the major threats for global biodiversity and understanding its potential effects on species distribution is crucial to optimise conservation planning in future scenarios under global change. Integrating detailed climatic data across spatial and temporal scales into species distribution modelling can help to predict potential changes in biodiversity. Consequently, this type of data can be useful for developing efficient biodiversity management and conservation planning. The provision of such data becomes even more important in highly biodiverse regions, currently suffering from climatic and landscape changes. The Transboundary Biosphere Reserve of Meseta Ibérica (BRMI; Portugal-Spain) is one of the most relevant reserves for wildlife in Europe. This highly diverse region is of great ecological and socio-economical interest, suffering from synergistic processes of rural land abandonment and climatic instabilities that currently threaten local biodiversity.
Aiming to optimise conservation planning in the Reserve, we provide a complete dataset of historical and future climate models (1 x 1 km) for the BRMI, used to build a series of distribution models for 207 vertebrate species. These models are projected for 2050 under two climate change scenarios. The climatic suitability of 52% and 57% of the species are predicted to decrease under the intermediate and extreme climatic scenarios, respectively. These models constitute framework data for improving local conservation planning in the Reserve, which should be further supported by implementing climate and land-use change factors to increase the accuracy of future predictions of species distributions in the study area.
Herein, we provide a complete dataset of state-of-the-art historical and future climate model simulations, generated by global-regional climate model chains, with climatic variables resolved at a high spatial resolution (1 × 1 km) over the Transboundary Biosphere Reserve of Meseta Ibérica. Additionally, a complete series of distribution models for 207 species (168 birds, 24 reptiles and 15 amphibians) under future (2050) climate change scenarios is delivered, which constitute framework data for improving local conservation planning in the reserve.
Le sport en Russie sous Vladimir Poutine : une religion orthodoxe ?
Authors: Aubin Lukas 
Published: June 2021

Pourquoi un aumônier orthodoxe suit-il l’équipe olympique russe partout dans le monde ? Dans quel but le patriarche Kirill de Moscou, la plus haute autorité religieuse du pays, fait-il régulièrement la promotion du sport dans les médias russes ? Assistons-nous à une sportivisation de la religion et à une théocratisation du sport en Russie ? Cet article vise à étudier les liens très forts qui existent entre le sport et la religion orthodoxe à l’ère de Vladimir Poutine. Si, dès 2000, le président russe a fait du sport un outil primordial de sa politique, il utilise également la religion orthodoxe comme une excroissance naturelle de son régime depuis le virage conservateur de 2012. Or, en juin 2018, l’inauguration par Kirill de la Commission patriarcale sur la culture physique et les sports institutionnalise la réalité religieuse d’un espace sportif longtemps resté athée. Désormais synchrones, les champs sportif et religieux en Russie semblent promis à une puissante synergie.
La barbarie lettrée, la république universelle et l’éducation intégrale
Authors: Vermeren Patrice 
Published: June 2021

Comment penser la Commune de Paris (1871) autrement que comme une révolution prématurée (Marx) ou comme ayant sauvé la République en France ? Si l’événement ne procède d’aucune nécessité historique, quel est le sens de l’énigme de cette affirmation inattendue d’un principe politique, sous le drapeau d’une République universelle, et qui voit tout un peuple de sans-noms se constituer comme sujets de l’émancipation dans l’existence en acte d’une puissance d’égalité et dans l’expérience inédite d’une démocratie contre l’État ?
Effectiveness of Applying Evidence-based Guidelines for Nurses Training on Nasogastric Tube Care
Authors: Chen Miao-Yen , Chou Shih-Ling , Mu Pei-Fan , Wang Su Chin , Chang Mei-Yu , Lin Hsiu-Hui , Chen Kee-Hsin , Hsu Shu-Yun , Chen Hsiang-Chun , Yang Kai-Ling , Lee Shu-Hui , Lu Ning-Jung 
Published: June 2021

Background:
This study formulated clinical guidelines for assessing nasogastric tube placement and for health education guidance according to evidence-based recommendations.

Method:
This study used a single group, pre- and postintervention design. Purposive sampling was used to recruit participants from nursing institutions in Taiwan.

Results:

Sixty-two individuals in charge of nursing institutions were recruited to participate in the in-service training program. Statistically significant differences were observed in the four major items in the self-directed learning readiness scale (
t
= 3.85,
p
< .00;
t
= 3.99,
p
< .00;
t
= 2.94,
p
< .01;
t
= 4.13,
p
< .00). With regard to program satisfaction, the mean score was 4.88 to 4.9 points. The mean score for teaching satisfaction was 4.94 to 4.9 points. Furthermore, the participants scored more than 80 points in the online course test and the nasogastric tube placement skill.

Conclusion:

The individuals in-charge are expected to be willing to apply and promote methods of literature collation and recommendation in their respective institutions.

[
J Contin Educ Nurs
. 2021;52(7):326–334.]
Victus Ordine Constituto: la alimentación en la medicina de Amato Lusitano, una aproximación
Authors: Pérez Ibáñez María Jesús , Recio Muñoz Victoria 
Published: June 2021

Parte de la tarea médica del portugués João Rodrigues de Castelo Branco, pseudónimo de Amato Lusitano (1511-1568), consiste en atender o modificar la dieta de sus pacientes. A través de las prescripciones de la Centuria Tertia, uno de los libros que componen su obra Curationum Medicinalium Centuriae, podemos ver el amplio número de alimentos utilizados con fines terapéuticos, algunos realmente costosos. También conocemos cómo la atención de este médico por la dieta exige la obediencia del paciente.
Las traducciones argentinas de Galeno: el caso de La Sangría
Authors: Durán Mañas Mónica 
Published: June 2021

El presente trabajo estudia las primeras traducciones de Galeno al español que se realizaron en Argentina, en el marco de un proyecto editorial dirigido por Aníbal Ruiz Moreno. La investigación pone de manifiesto que la colección en la que aparecen no era en realidad solo de obras de Galeno, sino una colección general con textos relevantes para la historia de la medicina. Se añade el caso concreto de La sangría como estudio de caso para una evaluación preliminar de la naturaleza de las traducciones ofrecidas por Ruiz Moreno y su equipo. El proyecto quedó inconcluso debido a la repentina muerte de su director por lo que quedaron algunos tratados galénicos sin publicar. El artículo aporta una hipótesis plausible sobre el destino de estas traducciones. Aníbal Ruiz Moreno, fue nada menos que el fundador, junto con Pedro Laín Entralgo, de la revista que hoy se llama Asclepio.
La Scala Graduum Caloris de Newton. Una simulación numérica
Authors: Simón Calero Julián 
Published: June 2021

Sir Isaac Newton, en la Scala graduum Caloris, publicada en 1701, presentaba una escala “con el grado de calor” de los cuerpos que extendía las medidas muy por encima de los valores disponibles en la época. Para determinarla, Newton siguió dos caminos. El primero usando un termómetro de dilatación con aceite de linaza como líquido, cuyas medidas seguían una progresión aritmética, pero cuyo máximo estaba limitado por la inflamación del aceite. El segundo, por un método completamente nuevo, que consistía en medir los tiempos de enfriamiento de un cuerpo previamente calentado en una pequeña cocina de carbón, y relacionar esos tiempos con las temperaturas según una nueva ley, lo que daba lugar a una escala que seguía una progresión geométrica. Ambas escalas se solapaban parcialmente, lo cual le permitió extender las medidas aritméticas hasta más de seis veces el punto de ebullición del agua. Esa nueva ley se conoce como “Ley de enfriamiento Newton”.
Aquí, pretendemos realizar una simulación numérica del proceso de enfriamiento del cuerpo caliente, conjeturando los instrumentos que pudo haber usado y las condiciones ambientales en que se realizó. Todo ello siguiendo lo que el propio Newton refleja en su artículo. Se terminará con unas reflexiones sobre la ley, que estimamos que la enunció en forma integral.
Búsqueda de señal orbital en isótopos estables de carbono y oxígeno de belemnites del Jurásico Inferior de la cuenca Vasco-Cantábrica mediante el periodograma suavizado de Lomb-Scargle
Authors: Polanco-Martínez Josué M. 
Published: June 2021

Los isótopos estables obtenidos de muestras fosilizadas de macrofósiles, como los belemnites, son unos de los pocos registros geológicos existentes del Jurásico Inferior, por lo cual han sido usados para reconstrucciones de temperaturas y salinidades del océano de esa época. Sin embargo, hasta la fecha no han sido utilizados para averiguar si estos paleoindicadores pudieron registrar algún tipo de evento periódico relacionado con los ciclos orbitales de la Tierra. Por esta razón y teniendo en cuenta varias de las limitaciones al utilizar estos tipos de datos, en este trabajo se presenta un novedoso estudio donde se aplica una técnica avanzada de análisis espectral conocida como el periodograma suavizado de Lomb-Scargle, la cual puede ser aplicada de modo directo a series temporales no equiespaciadas contaminadas por ruido. El objetivo de este trabajo es identificar la presencia de ciclos orbitales que se hayan podido registrar en series temporales de valores medios de δ18O y δ13C provenientes de muestras fosilizadas de belemnites recolectadas en la cuenca Vasco-Cantábrica teniendo en cuenta los errores de datación de estas muestras en la estimación del espectro. De manera especial se hace énfasis en la búsqueda de alguno de los ciclos de la excentricidad, como el de largo periodo localizado ca. 400 Ka o el de menor periodo localizado ca. 100 ka, porque se sabe que el ciclo de 400 Ka ha permanecido invariable desde el Mesozoico hasta el presente y porque ambos ciclos han sido identificados en registros estratigráficos del Mesozoico recolectados en diferentes áreas geográficas. Sin embargo, a pesar de la rigurosidad de nuestros análisis, no se encontró señal orbital de 400 Ka aunque si una localizada cerca de los 109 Ka, la cual podría estar relacionada con los ciclos de corto periodo de la excentricidad de la Tierra.
Education politics and contingency: Belief, status and trust behind the Finnish PISA miracle
Authors: Simola Hannu , Rinne Risto 
Published: June 2021

De nombreux concepts non historiques et décontextualisés tels que efficacité, responsabilité et qualité sont en train d’envahir le monde éducatif sans être remis en question, du fait de leur utilisation généralisée à travers le monde. L’éducation comparative continue à souffrir de certains déficits méthodologiques et d’une sous-théorisation prononcée. Dans cet article, nous tentons d’enrichir cette recherche à partir des concepts prometteurs de contingence, coincidence et Spielraum. Ces concepts nous serviront à présenter le succès finlandais dans les études PISA en illustrant trois croyances largement ancrées dans les débats nationaux en Finlande. Ces croyances paraissent uniques si on les compare à d’autres nations, et elles proviennent certainement de l’histoire nationale finlandaise. La première concerne la confiance forte des Finlandais en l’éducation ; la deuxième veut que le métier d’enseignant soit un métier très respecté dans ce pays ; et la troisième que les parents, autorités et hommes politiques ont confiance en l’école compréhensive finlandaise. Ces trois « vérités » nationales sont largement acceptées même si l’on trouve peu de preuves empiriques pour les justifier. Elles peuvent constituer sans aucun doute des éléments clefs de l’auto-perception nationale en relation à l’éducation. Dans cette contribution, nous questionnons les explications traditionnelles de type fonctionnaliste ou rationaliste de la recherche comparative en éducation.
La mère, la directrice, la pédagogue et la lectrice : de l’utilisation du sexe comme variable pédagogique chez Pauline Kergomard
Authors: Kolly Bérengère 
Published: June 2021

L’éducation maternelle dans l’école témoigne d’une proposition pédagogique nouvelle entendant puiser au sein de la famille, auprès des gestes maternels et des habitudes domestiques, des principes nouveaux pour l’école des tout-petits. Pauline Kergomard prend ainsi acte d’une circulation nécessaire entre famille et école, tout en établissant différenciation entre modèle réel et modèle philosophique : c’est en distance avec la mère réelle, mais ancrée dans le « génie maternel » que la directrice construit un type d’école nouveau. Cette distorsion entre réel et imaginaire révèle une particularité dans l’utilisation du sexe féminin, ici comme variable pédagogique. L’appartenance au sexe féminin de la mère, de la directrice, de la pédagogue elle-même et de ses lectrices, parce que comprise comme une variable historique et non biologique, peut ainsi devenir un levier d’innovation et de création, dans les conceptions et les pratiques pédagogiques.
Facile Synthesis of a Pt(IV) Prodrug of Cisplatin and Its Intrinsically 195mPt Labeled Analog
Authors: Sharma K. Shitaljit , Vimalnath K. V. , Phadnis Prasad P. , Chakravarty Rubel , Chakraborty Sudipta , Dash Ashutosh , Vatsa Rajesh K. 
Published: June 2021

Background, Aims and Objectives:
Cisplatin is extensively used in chemotherapy for treatment of a broad range of cancers. But its undesired side reactions with biomolecules that lead to severe side effects especially on kidney and nervous system, are limiting its clinical utility. To reduce its side effects, the kinetically inert Pt(IV) prodrug was recognized as an alternative approach from satisfactory results of preliminary experiments. But, its approval as anticancer drug for clinical use requires detailed investigations of its anticancer action and pharmacological pathways by employing its analogue which can be traced by a suitable technique. As a step closer towards translation of Pt(IV)-based prodrug from research to clinical level, a protocol for efficient synthesis of 195mPt-radiolabeled Pt(IV) prodrug was devised.

Materials and Methods:
In order to achieve the aim, we started synthesis from elemental platinum avoiding lengthy steps. The synthesis protocol was standardized on its cold analogue, as [PtCl2(NH3)2(OCOCH2CH2COOH)2] which has been characterized with nuclear magnetic resonance (1H, 13C{1H} and 195Pt{1H}) spectroscopy, microanalyses and cyclic voltammetry. Also, cytotoxicity of [PtCl2(OCOCH2CH2COOH)2(NH3)2] was evaluated against MCF-7 human breast cancer cell lines using cisplatin as test control.

Results:
Intrinsically, 195mPt-labeled analogue of prodrug was obtained with high radionuclidic and radiochemical purity. It was confirmed by chromatography and γ-ray spectrometry.

Conclusion:
The 195mPt-radiolabeled prodrug was synthesized in a facile manner. It can be utilized in evaluating the mechanism of anticancer action and pharmacokinetics by enabling synergistic use of molecular imaging and targeted drug delivery.