bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterization of the aromatic profile of Ruché wine from Piedmont (Italy) with gas chromatography–mass spectrometry and unsupervised machine learning techniques
Authors: Orecchio Ciro , Rabezzana Roberto , Vincenti Marco , Bonometti Elisabetta , Laurenti Enzo , Operti Lorenza , Rigoletto Monica 
Published: December 2024

AbstractBACKGROUNDThe volatile composition of Ruché, a red wine produced from a native grape in Piedmont (Italy), was investigated using headspace‐solid phase microextraction (SPME) coupled to gas chromatography–mass spectrometry (GC/MS). The main volatile compounds of the wine were identified and quantified. Chemometric techniques were applied to identify features and possible clusters among the different samples.RESULTSForty volatile compounds were unambiguously identified in the 36 wine samples from different producers. The aroma profile was mainly composed of different alcohols and esters but also featured appreciable concentrations of terpenes, aldehydes, and octanoic acid. 2‐Methyl benzaldehyde was identified for the first time. A high concentration of isoamyl alcohol significantly contributed to the aroma complexity. Differences between producers are highlighted.CONCLUSIONThe present work is the first report about the volatile profile of Ruché wines investigated by chemometric methods with quantitative results. Multivariate exploratory approaches revealed minor but distinct differences among the studied wines, likely attributable to variations in winemaking procedures. This study could be developed in future by investigating possible differences between wines according to different production vintages. © 2024 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Collagen peptides alleviate estrogen deficiency‐induced osteoporosis by enhancing osteoblast differentiation and mineralization
Authors: Yang Qi , Mu Zhishen , Ma Xiaoyu , Yang Ximing , Fu Baifeng , Chang Zhihui , Cheng Shuzhen , Du Ming 
Published: December 2024

AbstractBACKGROUNDOsteoporosis is a systemic skeletal disorder characterized by decreased bone mass and impaired bone microarchitecture because of an imbalance between bone resorption and formation. Existing pharmacological treatments often have significant side effects and mainly focus on inhibiting bone resorption. Other than inhibiting osteoclast‐mediated bone resorption, the present study also investigates the potential role of sheepskin collagen peptide (SSCP) in bone formation by promoting osteoblast proliferation, differentiation and mineralization.RESULTSSSCP improved bone mineral density in ovariectomized mice by improving bone volume, trabecular thickness and trabecular number. Histological analysis and tartrate‐resistant acid phosphatase (TRAP) staining revealed denser trabeculae and decreased osteoclast activity, accompanied by a normalized receptor activator of nuclear factor kappa‐B ligand/osteoprotegerin ratio and reduced serum TRAP levels. SSCP promotes the proliferation, differentiation and mineralization of MC3T3‐E1 osteoblast cells by upregulating osteogenic markers such as bone morphogenetic protein (BMO)‐2, runt‐related transcription factor (RUNX)‐2 and β‐catenin. SSCP enhanced bone formation and suppressed bone resorption by activating the WNT/β‐catenin and BMP/Smad signaling pathways.CONCLUSIONSSCP offers a dual modulatory approach to bone health, addressing both bone formation and resorption. Its activation of key osteogenic pathways and improvement in bone structural integrity highlight its therapeutic potential for managing osteoporosis and enhancing skeletal health. By activating key osteogenic pathways and normalizing bone metabolism markers, SSCP presents a promising therapeutic candidate for osteoporosis and other bone‐related conditions. Further clinical studies are needed to confirm these findings and explore its potential applications. © 2024 Society of Chemical Industry.
Elevated CO2 in dynamic controlled atmosphere storage: Impact on anaerobic metabolism and overall quality of ‘Maxi Gala’ apples
Authors: Schultz Erani Eliseu , Soldateli Francis Júnior , Both Vanderlei , Brackmann Auri , Batista Carine Borges , Thewes Fabio Rodrigo , Mallmann Wendt Lucas , Berghetti Magno Roberto Pasquetti , Ludwig Vagner , Thewes Flavio Roberto 
Published: December 2024

AbstractBACKGROUNDThe present study investigated the effects of high CO2 partial pressures (pCO2) in dynamic controlled atmosphere monitored by respiratory quotient (DCA‐RQ 1.3) on the anaerobic metabolism compounds, physiological disorders and overall quality of ‘Maxi Gala’ apples after 9 months of storage (2.0 °C), plus 7 days of shelf life (20 °C). Two experiments were conducted over 2 years. In the first year, ‘Maxi Gala’ apples were stored under controlled atmosphere (CA – 1.2 kPa O2 + 2.0 kPa CO2), CA + 1‐methylcyclopropene (1‐MCP), DCA by chlorophyll fluorescence (DCA‐CF + 1.2 kPa CO2) and DCA‐RQ 1.3 with different pCO2 (0.4, 1.2, and 1.6). The same treatments were evaluated in the second year, with addition of DCA‐RQ 1.3 + 2.0 kPa CO2.RESULTS‘Maxi Gala’ apple stored under DCA‐RQ 1.3 + 0.4 kPa CO2 and DCA‐CF maintained healthy fruit amount similar to DCA‐RQ 1.3 + 1.2 and 1.6 kPa CO2, but with lower flesh firmness. DCA‐RQ 1.3 with higher pCO2 (1.6 or 2.0) increases the production of ethyl acetate, but did not impact physiological disorders compared to DCA‐CF. CA + 1‐MCP maintained high flesh firmness, but reduced healthy fruit amount.CONCLUSIONThe present study has demonstrated that DCA‐RQ 1.3 with 1.6 or 2.0 pCO2 can be adopted for ‘Maxi Gala’ apples storage, resulting in similar or better fruit quality than DCA‐RQ 1.3 + 1.2 kPa CO2. Additionally, the adoption of high pCO2 in the DCA‐RQ storage system can result in cost reductions related to CO2 adsorption. © 2024 Society of Chemical Industry.
Effects of Rurality, Socioeconomic Status, and Race on Head and Neck Squamous Cell Carcinoma Outcomes
Authors: Torres‐Small Sofia , Davies Camron , Kumsa Fekede Asefa , Maroda Andrew , Shaban‐Nejad Arash , Gleysteen John P. , Schwartz David L. , Wood C. Burton 
Published: December 2024

ObjectiveTo examine how rural residence interacts with SES and race/ethnicity relative to Head and neck squamous cell carcinoma (HNSCC) treatment delay and outcomes.MethodsThe SEER database was queried for patients aged ≥18 with HNSCC. Out of 164,337 cases, 126,052 remained after exclusions for missing data. Statistical tests performed included Chi‐squared tests, log‐binomial regression models, and parametric accelerated failure time (AFT) models, with a significance level of α < 0.05.ResultsAbout 38% of patients residing in lowest SES census tracts were rural, whereas over 98% of patients from highest SES tracts were urban. Delayed treatment was associated with shorter median survival [aTR = 0.968, 95% confidence interval (CI): 0.939, 0.999]. Risk for treatment delay increased with decreasing SES and was greater for those with minoritized race/ethnicity status. Rurality was associated with a lower risk [aRR: 0.917, 95% CI: 0.892, 0.946] of treatment delays but was not predictive for patient survival (aTR: 1.019 [0.978, 1.061]). Cancer‐specific mortality increased with decreasing SES and was higher in patients with minoritized race/ethnicity status.ConclusionRurality was associated with decreased risk for treatment delay but not with worse survival relative to urban residence, whereas low SES and minority status remained predictive for poor outcome regardless of geographic context (level of evidence: 4). Although these findings argue against HNSCC survival deficits specific to rural populations, there remains concern regarding potential care shortfalls in rural populations not detected in this sample. Confirmatory patient‐level analysis should be prioritized to optimize support along the rural/urban divide.Level of EvidenceIV Laryngoscope, 2024
Lignin Derivative as Visible‐Light Photo‐Initiating System for the Development of Biocide Materials under Light Irradiation
Authors: Elian Christine , Mouhoubi Fares , Moilleron Régis , Andaloussi Samir Abbad , Ha‐Thi Minh‐Huong , Chiappone Annalisa , Cosola Andrea , Lajnef Sonia , Peyrot Fabienne , Versace Davy‐Louis 
Published: December 2024

AbstractThe design of a new visible‐light methacrylated‐based kraft lignin photosensitizer (MAcL) of iodonium salt (Iod) for the free‐radical polymerization (FRP) of polyethylene glycol dimethacrylate (PEGDMA) under LEDs@405, 455, 470, 505, and 530 nm is reported. As demonstrated by laser flash photolysis (LFP) and electron paramagnetic resonance spin‐trapping (EPR ST) experiments, the combination of MAcL with an electron acceptor (Iod) and trimethylolpropane tris(3‐mercaptopropionate) (TT) used as a crosslinker, leads to the formation of highly efficient initiating radicals, i.e., thyil and carbon‐centred radicals, promoting thus the FRP of PEGDMA. The final methacrylate conversions of PEGDMA are very high and range from 80 to 95% under LED@530 nm and LED@405 nm, respectively. For the first time, MAcL is also used as a biocide agent as it produces singlet oxygen when exposed to visible light. The resulting photoinduced bio‐based materials incorporating MAcL demonstrate tremendous antibacterial properties against Staphylococcus aureus (S. aureus), inducing 100% bacterial death.
Interface microstructure and mechanical properties of selective laser melting‐formed CuCrZr alloy for 316 L stainless steel
Authors: Wang Y. , Liu B. , Tang Q. , Huo W. , Li Z. , Bai Y. 
Published: December 2024

AbstractA bimetallic structure combines the properties of two constituent materials and has a high comprehensive performance. Selective laser melting has been widely studied for its advantages such as high utilization of raw materials, short processing cycles, and the ability to form complex structures. The 316 L‐CuCrZr bimetallic structure was successfully prepared using selective laser melting. Its microstructural analysis and energy spectrum analysis indicated that the 316 L stainless steel and the CuCrZr alloy formed a good interfacial bond and that the elements at the interface exhibited a gradient distribution. The tensile strength of 316 L‐CuCrZr was 280.97 MPa, which was close to the strength of the CuCrZr alloy. The interface hardness showed a decreasing trend from that of the stainless steel to that of the copper alloy, which indicated that the interface between the 316 L stainless steel and the CuCrZr alloy was well bonded.
Parasympathetic Dysfunction Prevails in GBA1‐Associated Parkinson's Disease
Authors: De Santis Tiziana , Cocco Antoniangela , Castiglioni Paolo , Ferrarin Maurizio , Mineri Rossana , Morenghi Emanuela , Avenali Micol , Albanese Alberto 
Published: December 2024

AbstractBackgroundThe role played by sympathetic and parasympathetic autonomic branches in patients with Parkinson's disease carrying variants in the GBA1 gene (GBA‐PD) is still elusive.ObjectivesTo characterize cardiovascular autonomic function in GBA‐PD and I‐PD patients with early and mid‐stage disease.MethodsThese assessments were performed: cardiovascular autonomic tests, analysis of heart rate and blood pressure variability, cardiac noradrenergic imaging. The frequency and severity of autonomic symptoms were comparatively assessed with the SCOPA‐AUT questionnaire.ResultsCompared to the I‐PD cohort, GBA‐PD patients displayed an increased burden of autonomic symptoms. Autonomic tests revealed worse parasympathetic scores in GBA‐PD while sympathetic indexes and the degree of cardiac sympathetic binding were comparable in the two groups. Heart rate variability indexes also revealed lower vagal modulation in the GBA‐PD group.ConclusionsThe cardiovascular autonomic profile in GBA PD is characterized by a prominent cardiovagal dysfunction compared to I‐PD.
CMMSE: Solutions in a Broad Sense to the Boundary Value Problem for First‐Order Partial Differential Systems
Authors: Bekbauova Altynshash 
Published: December 2024

ABSTRACTThis article examines the initial‐boundary value problem for a system of first‐order partial differential equations. Issues of existence and uniqueness of the solution in a broad sense are considered, while taking into account both periodic and multipoint conditions. The definition of a solution in a broad sense is introduced; the initial problem is reduced to the initial‐boundary value problem for ordinary differential equations. The two‐point boundary value problem for ordinary differential equations systems is studied by the Dzhumabaev method (parameterization method), which allows us to move on to the equivalent multipoint boundary value problem with functional parameters. An algorithm to find an approximate solution to the problem in a broad sense has been developed.
A liberalized diet does not improve caloric intake during neutropenia in patients undergoing hematopoietic stem cell transplants: A prospective randomized controlled trial
Authors: Schulz Jenna N. , McGee Kristina H. , Weaver Michael T. , Wingard John R. , Williams Precious D. , Cline Christina L. , Farhadfar Nosha , Lynch‐Kelly Debra , Al‐Mansour Zeina A. , Dahl Wendy J. 
Published: December 2024

AbstractBackgroundThe neutropenic diet has been a long‐standing approach to preventing infection in patients with hematopoietic stem cell transplants (HSCTs), although data on its efficacy are inconclusive and its restrictive nature might contribute to harm by reducing dietary intake in this patient population who typically experiences poor oral intake. The aim was to determine if a liberalized diet (LD), in comparison with a neutropenic hospital diet (ND), would improve energy intake and lessen weight loss during neutropenia in patients with HSCTs.MethodsA randomized controlled trial was conducted in a single‐center HSCT/hematologic malignancy unit. The diet interventions were initiated when absolute neutrophil counts dropped to <500 cells/mm3; oral dietary intake was assessed during neutropenia until neutrophil recovery, which averaged 9.5 days.ResultsMeal intake compliance (consuming at least 50% of meals/day) was not different between groups (LD, 47%; ND, 43%; P = 0.66). Of the 191 patients assessed (LD, n = 92; ND, n = 99), mean (SD) energy, 678 (349) vs 724 (393) kcal/d (P = 0.46), and protein, 30.3 (18.5) vs 30.4 (18.1) g/day (P = 0.89) did not differ between groups nor did weight change, 0.3 (2.5) vs 1.2 (4.1) kg (P = 0.22) during neutropenia. None vs higher than or equal to grade 1 mucositis, allogeneic vs autologous stem cell transplantation, and fewer days on intervention favored higher energy and protein intakes.ConclusionEnergy intake during neutropenia did not improve with a LD encouraging fresh fruits and vegetables. Thus, alternative approaches to improving dietary intake, such as energy‐dense and nutrient‐dense foods with sensory characteristics acceptable to patients experiencing significant mucositis, require exploration.
Transformation towards the sustainable management of peatlands: A characterisation of farmers in the Teufelsmoor, Germany
Authors: Hünnebeck‐Wells Amelie , Loos Jacqueline , Abel Susanne , Nordt Anke 
Published: December 2024

Abstract

Peatland restoration through rewetting is a pivotal solution to counteract the climate crisis.

Since many peatlands with the potential for rewetting are farmland, rewetting can only be achieved in collaboration with peatland farmers. However, the discord between the need to rewet peatlands and the implementation of rewetting measures calls for a transformation in how peatlands are managed.

To explore their willingness towards rewetting, interviews were conducted with 19 peatland farmers in the Teufelsmoor, Germany. Here, we categorised the perceptions, challenges and opportunities of rewetting as operational impediments, knowledge and awareness of peatlands and rewetting, collaboration between stakeholders and peatland perceptions and sense of identity.

Based on these results, we characterised peatland farmers as Pioneers, Sceptics, Pragmatists and Hobby Farmers.

This characterisation showcases peatland farmers as a group with differing perceptions towards rewetting and highlights the need for different approaches to foster a transformation to agriculture that works with peatlands and peatland farmers to ameliorate the climate crisis.

Read the free Plain Language Summary for this article on the Journal blog.
Effects of different nano‐SiO2/silane coupling agent “rigid‐flexible” hybrid interfaces on the mechanical performance of basalt fiber/epoxy composites
Authors: Jiang Lin , Yang Yunhui , Sheng Jie , Li Yongzhe , Huang Zhengqiang , Li Jiquan , Geng Tie 
Published: December 2024

AbstractPoor interfacial compatibility is a key factor limiting the mechanical properties of basalt fiber reinforced polymer composites (BFRPs). Constructing hybrid interfaces that combine rigid nanoparticles with flexible sizing agents presents a promising strategy to enhance these properties. In this study, we first identified the most suitable coupling agent from a series of candidates, including amino, epoxy, and methacryloxy functional groups. Using the selected coupling agent as a flexible sizing agent and inorganic nano‐SiO2 as the rigid component, two types of interfaces were developed: a homogeneous organic/inorganic hybrid interface and a gradient‐modulus structure, which were fabricated via direct deposition and in‐situ growth methods, respectively. The results demonstrated that BFRPs with gradient modulus interface effectively absorb and dissipate crack energy under loading, resulting in significantly improved mechanical properties. The interlaminar shear strength (ILSS), tensile strength, and flexural strength increased to 56.24, 541, and 793 MPa, respectively, representing improvements of 40.81%, 15.35%, and 32.38%. Fracture morphology analysis further confirmed the reinforcement mechanism of the “rigid‐flexible” hybrid interfaces. This work can provide valuable insights for developing high‐performance basalt fiber‐reinforced composites.Highlights
Suitable silane coupling agent was selected for basalt fiber (BF) reinforced epoxy composites.
Organic/inorganic hybrid and gradient modulus interfaces were established.
Uniformly distributed SiO2 and fully covered silane boosts interfacial bonding.
Interfacial, tensile and flexural properties of modified BFRPs all improved.
Machine learning‐driven optimization and prediction of poly(lactic acid)/poly(butylene‐adipate‐co‐terephthalate)/clay blend nanocomposites in structure–property relationships: A combination of experimental and computational techniques
Authors: Akbarzadeh Mahsa , Gorji Tayebeh , Tayouri Mohammad Iman , Estaji Sara , Akbari Homa , Ahmadi Zahed , Dawi Elmuez A. , Khonakdar Hossein Ali 
Published: December 2024

AbstractThe melt‐mixing method in a twin screw extruder was utilized to develop blended nanocomposites of poly(lactic acid: PLA) and poly(butylene‐adipate‐co‐terephthalate: PBAT) with three combinations of weight percent 90/10, 70/30, and 50/50 (w/w) which contain 1, 3, and 5 phr of organic clays (Cloisite 30B). As a result, both x‐ray diffraction analysis and scanning electron microscopy revealed a consistent compatibilization effect of the nanoclays (NCs) within the PLA/PBAT matrix. The interfacial adhesion between the blend components is improved in matrix droplet structures, where the PBAT domains are evenly dispersed owing to the uniform dispersion of NCs at optimal 3 phr. Furthermore, NCs at this concentration acted as nucleating agents in the PLA/PBAT blends and enhanced the crystallization rate of the blend nanocomposites by lowering the cold crystallization temperature of the 90/10 blend by 5°C, as determined by differential scanning calorimetry (DSC). The neat PLA/PBAT blends displayed a drop in tensile strength and modulus, but their properties were restored when NCs were interfacially localized. In addition, elongation at the break point increased from ∼5.5% (70/30) to ∼5.9% (70/30/1). A comparison was also made between the theoretical values of the tensile modulus calculated using three‐phase mathematical models and the experimental results. According to the Carreau‐Yasuda model, the viscosity of blend nanocomposites increases with the addition of NC. The percolation threshold between the two filler contents was also elucidated as the storage modulus increased significantly from 70/30 (∼28 Pa) to 70/30/3 (∼2000 Pa) at low frequency. Furthermore, machine learning (ML) has been demonstrated to be an effective tool for data‐driven multi‐physical modeling that can be exploited to optimize rheological properties. The extreme gradient boosting (XGBoost) model yields the most accurate viscosity (η) prediction. Finally, the thermal stability of the blended components was examined via thermogravimetry analysis (TGA) and was found to be improved with the use of NCs.Highlights
Structure–property models were developed by experimental and computational data.
Young's modulus was predicted with high accuracy by Paul and Halpin‐Tsai models.
XGBoost modeled the rheological data well based on the machine learning technique.
Simultaneous improvement of thermal and mechanical properties of PP/SEBS/clay nanocomposite produced by Fused Filament Fabrication method
Authors: AbdulAmeer S. , Altalbawy Farag M. A. , Adhab Ali Hussein , Rachchh Nikunj , Tham Jacquline , Kumar Raman , Kulshreshta Ankur , Chandra Subhash , Mahdi Morug Salih , Mansoor Aseel Salah , Radi Usama Kadem , Abd Nasr Saadoun 
Published: December 2024

AbstractThe aim of the work described in this paper is to improve the thermal stability and mechanical properties of polypropylene (PP)/styrene‐ethylene‐butylene‐styrene (SEBS)/clay nanocomposites fabricated by fused filament fabrication (FFF). The response surface method is used to investigate the effect of print speed, nozzle temperature, and nano‐clay content on the thermal stability, tensile strength, and impact resistance of the PP/SEBS/clay nanocomposite. In addition, the microstructure of the printed samples was analyzed by SEM and TEM images. Increasing the nano‐clay amount significantly enhanced the melting temperature of the nanocomposite, while increasing nozzle temperature and print speed had a slight influence on the melting temperature. Moreover, the highest tensile strength of the nanocomposite was attained at a clay content of 3 wt%, due to the good distribution of the nanoparticles in the PP matrix. The impact resistance of the nanocomposite was also enhanced with an increase in print speed, while an increase in nozzle temperature and clay content reduced the impact resistance. The optimization results indicated that the melting temperature, tensile strength, and impact resistance of the PP/SEBS/clay nanocomposite can be enhanced simultaneously by a print speed of 80 mm/s, nozzle temperature of 242°C and nano‐clay content of 3.2 wt%.Highlight
Fabrication of PP/SEBS/clay nanocomposite using the FFF process.
Studying the effect of FFF parameters on the thermal and mechanical properties.
Predicting the optimum values of the FFF parameters.