bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mucopolysaccharidosis patients have reduced functional capacity
Authors: Dias Bianca M. C. , Lanza Fernanda C. , Santos Jenifer dos , Aranda Carolina S. , Solé Dirceu , Martins Ana Maria , Wandalsen Gustavo F. 
Published: November 2021

AbstractIntroductionMucopolysaccharidoses (MPSs) are a group of rare diseases caused by an intralysosomal accumulation of glycosaminoglycans, resulting in a multisystemic clinical condition characterized by variable degrees of physical‐functional impairment.ObjectiveTo evaluate the functional capacity (FC) of MPS patients and compare with a healthy control group.MethodsThis is a cross‐sectional study of 6‐ to 39‐year‐old patients followed at a medical reference center and compared with their control peers, matched by age and sex. FC was assessed using the Sit‐to‐Stand Test (SST) and Incremental Shuttle Walk Test (ISWT). Heart rate (HR) and Borg rating of perceived exertion were measured before and after ISWT. HR recovery (HRR) was defined as the HR at the end of the test minus the HR in the second minute after ISWT.ResultsNineteen (19) MPS patients, 69% with type II MPS and mean age 17 ± 11 years were evaluated. Every patient was under enzyme replacement therapy. The time to perform the SST was longer in the MPS group (10.6 ± 2.5 s vs. 6.7 ± 1.2 s; p < .01). The MPS group achieved lower values of distance covered on the ISWT (407.6 ± 329.8 m vs. 1131.9 ± 183.3 m; p < .01), with a significantly higher Borg (6 [5–8] vs. 2 [1–4]; p = .02). The MPS group's HRR was slower than the controls (32.9 ± 20.2 beats per minute [bpm] vs. 69.1 ± 25.9 bpm; p < .001).DiscussionWe observed a pronounced reduction in the MPS group's FC compared to their healthy peers and a worse HRR after completing the test.
FNAOSiPPEA[]/Zn(II) as a Bifunctional Lewis Acid/ Bronsted Base Heterogeneous Magnetic Nanocatalyst Based on Nano‐Almond Shell for Synthesis of Naphtho[1,3]oxazine Derivatives**
Authors: Mallah Dina , Mirjalili BiBi Fatemeh 
Published: November 2021

AbstractFe3O4@nano‐almondshell@OSi(CH2)3/2‐(1‐piperazinyl)ethylamine/Zn(II) abbreviated (FNAOSiPPEA/Zn(II)) as a Lewis acid/ Bronsted base double‐layer magnetic nano‐catalyst was prepared by immobilization of Zn‐diamine complex on functionalized nano‐almondshell coated Fe3O4 NPs. The properties of the FNAOSiPPEA/Zn(II) nano‐catalyst were identified by the of FT‐IR, FESEM, TGA, EDS‐MAP, XRD, VSM, and BET techniques. The catalytic performance of FNAOSiPPEA/Zn(II) as a strong and effective Lewis acid for the synthesis of 2‐aryl(alkyl)‐2,3‐dihydro‐1H‐naphtho[1,2‐e][1,3]oxazine derivatives, abbreviated ADNO, was evaluated. A three‐component reaction between formaldehyde, primary amines, and phenolic compounds such as β‐naphthol, α‐naphthol, phenol, and hydroquinone was occurred in this protocol. FNAOSiPPEA/Zn(II) can be reused four times with a slight loss of catalytic activity.
Study on the Modification of Polyvinylidene Fluoride Films with Barium Zirconate Titanate to Achieve Excellent Dielectric Property
Authors: Qu Jiale , Gao Shen , Hou Zhenghao 
Published: November 2021

AbstractThe barium zirconate titanate coated with dopamine is an excellent dielectric material. Herein, we prepared a type of BaLaZrTiO3 (BLZT) powder by hydrothermal method and coated BLZT with dopamine (DA). Then, casting method was applied to synthesize a composite film by adding BLZT/DA‐BLZT powders to polyvinylidene fluoride (PVDF) respectively. Results show that DA‐BLZT@PVDF films perform better than BLZT@PVDF films in term of energy storage property and dielectric property. The dielectric constant and energy storage density of DA‐BLZT@PVDF films were all higher than that of BLZT@PVDF films and the dielectric loss was lower than BLZT@PVDF films. X‐Ray Diffraction (XRD) demonstrated the typical perovskite structure was existing in BLZT powder. TEM and SEM also showed that the surface of BLZT powder was successfully coated with DA and uniformly dispersed in PVDF. This research provided an avenue to significantly improve the electrical properties of composite films.
Exploring the Properties of H2O@C60 with the Local Second‐Order Møller‐Plesset Perturbation Theory: Blue or Red Shift in C60 and H2O Fundamentals to Expect?
Authors: Dolgonos Grygoriy A. 
Published: November 2021

AbstractThe main structural, energetic and vibrational properties of H2O@C60 were computationally investigated using the density‐fitting local second‐order Møller–Plesset (DF‐LMP2) theory. Two low‐energy isomers, of C2 and C1 symmetry, were initially considered and only the latter one was identified as a true minimum with the lowest energy. The energy difference between these isomers was rather small (only 0.002 kcal/mol) and the respective interaction energy of any of the H2O@C60 isomers was −14.26 kcal/mol. These isomers were structurally similar having larger values of O−H bond lengths and angles by 0.0082 Å and 0.9 degrees, respectively, compared to a free water molecule. The calculated harmonic IR spectrum of the C1 isomer was characterized by: a) the presence of water frustrated translation frequencies at 90.5‐94.3 cm−1; b) the red shift in frequency of the first radial C60 mode (by −(1.8–2.7) cm−1) and the blue shift for the other three IR‐active C60 modes (by up to 2.2 cm−1); c) the red shift in H2O fundamentals by −19.2, −110.4 and −123.8 cm−1 for the bending, symmetric and antisymmetric mode, respectively, in excellent agreement with recently reported experimental results. The zero‐point energy contributed only 0.15 kcal/mol to the ZPE‐corrected value of H2O@C60 interaction energy which became now equal to −14.11 kcal/mol.
Fe(OTf)3‐Catalyzed Cyanation of Isochromene Acetals with Trimethylsilyl Cyanide
Authors: Zhan Huilin , Hou Meifeng , Li Yulin , Chen Zuliang , Wei Yingjing , Liu Suijun 
Published: November 2021

AbstractAn efficient Fe(OTf)3‐catalyzed nucleophilic addition of trimethylsilyl cyanide (TMSCN) to isochromene acetals has been achieved for the synthesis of 1‐cyano‐isochromenes. In the presence of 1–20 mol% Fe(OTf)3, a various of 1‐cyano‐isochromenes were obtained in good to excellent yields at room temperature. This transformation provides a simple and mild methodology for the synthesis of 1‐cyano‐isochromenes.
A Designed Lithiophilic Carbon Channel on Separator to Regulate Lithium Deposition Behavior
Authors: Xu Sainan , Zhao Teng , Ye Yusheng , Yang Tianyu , Luo Rui , Li Li , Wu Feng , Chen Renjie 
Published: November 2021

AbstractIssues with unstable SEI formation and uncontrollable lithium dendrite growth impede the practical use of lithium anode in high‐energy batteries. Herein, a lithiophilic carbon channel on separator is designed to regulate lithium deposition behavior. The designed channel is formed by carbon nanosheet with cubic cavity (CNCC) prepared by hard template method. The CNCC with a large specific surface area and good electrolyte wettability can effectively reduce the local current density. Besides, the CNCC coated separator with high Young's modulus can mechanically inhibit the growth of lithium dendrites. Notably, CNCC coating can become lithiophilic during lithium plating/striping process, which is beneficial for homogeneous lithium deposition and low lithium nucleation overpotential. As a result, based on the CNCC coated separator, the symmetric Li|Li cell cycle over 2600h at 6 mA cm−2 for 2 mAh cm−2, while the Li|Cu cell reaches average Coulombic efficiency of 98.5% at 2 mA cm−2 for 2 mAh cm−2.
Uncommon Supramolecular Phosphorescence‐Capturing Assembly Based on Cucurbit[8]uril‐Mediated Molecular Folding for Near‐Infrared Lysosome Imaging
Authors: Huo Man , Dai Xian‐Yin , Liu Yu 
Published: November 2021

AbstractThe construction of highly effective phosphorescence energy transfer capturing system still remains great challenge in aqueous phase. Herein, a high‐efficiency supramolecular purely organic room temperature phosphorescence (RTP)‐capturing system via a secondary assembly strategy by taking advantage of cucurbit[8]uril (CB[8]) and amphiphilic calixarene (SC4AH) is reported. Comparing with free bromonaphthalene‐connected methoxyphenyl pyridinium salt (G), G⊂CB[8] exhibits an emerging RTP emission peak at 530 nm. Moreover, G⊂CB[8] further interacts with SC4AH to form the ternary assembly G⊂CB[8]  @  SC4AH accompanied by remarkably enhanced RTP emission. Interestingly, RTP‐capturing systems with delayed near‐infrared (NIR) emissive performance (635, 675 nm) are feasibly acquired by introducing Nile Red (NiR) or Nile Blue (NiB) as the acceptor into hydrophobic layer of G⊂CB[8] @ SC4AH, possessing ultrahigh antenna effects (352.9, 123.5) at a high donor/acceptor ratio (150:1, 300:1). More importantly, cell experiments indicate that G⊂CB[8]  @  SC4AH/NiB not only hold low cytotoxicity but also can successfully realize NIR lysosome‐targeted imaging of A549 cancer cells. This RTP‐capturing system of delayed NIR emission via multistage assembly strategy offers a new approach for NIR imaging in living cells.
Realizing Enhanced Thermoelectric Performance and Hardness in Icosahedral Cu5FeS4−xSex with High‐Density Twin Boundaries
Authors: Wang Huan , Zheng Sikang , Wu Hong , Xiong Xin , Xiong Qihong , Wang Hengyang , Wang Yang , Zhang Bin , Lu Xu , Han Guang , Wang Guoyu , Zhou Xiaoyuan 
Published: November 2021

AbstractBornite (Cu5FeS4) is an Earth‐abundant, nontoxic thermoelectric material. Herein, twin engineering and Se alloying are combined in order to further improve its thermoelectric performance. Cu5FeS4−xSex (0 ≤ x ≤ 0.4) icosahedral nanoparticles, containing high‐density twin boundaries, have been synthesized by a colloidal method. Spark plasma sintering retains twin boundaries in the pellets sintered from Cu5FeS4−xSex colloidal powders. Thermoelectric property measurement demonstrates that alloying Se increases the carrier concentration, leading to much‐improved power factor in Se‐substituted Cu5FeS4, for example, 0.84 mW m−1 K−2 at 726 K for Cu5FeS3.6Se0.4; low lattice thermal conductivity is also achieved, due to intrinsic structural complexity, distorted crystal structure, and existing twin boundaries and point defects. As a result, a maximum zT of 0.75 is attained for Cu5FeS3.6Se0.4 at 726 K, which is about 23% higher than that of Cu5FeS4 and compares favorably to that of reported Cu5FeS4‐based materials. In addition, the Cu5FeS4−xSex samples containing twin boundaries also obtain improved hardness compared to the ones fabricated by melting‐annealing or ball milling. This work demonstrates an effective twin engineering‐composition tuning strategy toward enhanced thermoelectric and mechanical properties of Cu5FeS4‐based materials.
Optimized Pt Single Atom Harvesting on TiO2 Nanotubes—Towards a Most Efficient Photocatalyst
Authors: Wu Zhenni , Hwang Imgon , Cha Gihoon , Qin Shanshan , Tomanec Ondřej , Badura Zdenek , Kment Stepan , Zboril Radek , Schmuki Patrik 
Published: November 2021

AbstractIn the present work the authors show that anodic TiO2 nanotubes (NT) show excellent harvesting properties for Pt single atoms (Pt SAs) from highly dilute Pt solutions. The tube walls of anodic nanotubes, after adequate annealing to anatase, provide ample of suitable trapping sites—that is, surface Ti3+‐Ov (Ov: oxygen vacancy) defects that are highly effective to extract and accumulate Pt in the form of SAs. A saturated (maximized) SA density can be achieved by an overnight immersion of a TiO2 NT layer to a H2PtCl6 solution with a concentration that is as low as 0.01 mm Pt. Such TiO2 NTs with surface trapped Pt SAs provide a maximized high activity for photocatalytic H2 generation (reaching a turnover frequency (TOF) of 1.24 × 106 h−1 at a density of 1.4 × 105 Pt atoms µm−2)—a higher loading with Pt nanoparticles does not further increase the photocatalytic activity. Overall, these findings show that anodic TiO2 nanotubes provide a remarkable substrate for Pt extraction and recovery from very dilute solutions that directly results in a highly efficient photocatalyst, fabricated by a simple immersion technique.
Engineered Platelet‐Based Micro/Nanomotors for Cancer Therapy
Authors: Li Ting , Chen Tiantian , Chen Huan , Wang Qi , Liu Zhiyong , Fang Leyi , Wan Mimi , Mao Chun , Shen Jian 
Published: November 2021

AbstractEngineered platelets (PLT) can bring new possibilities for diseases treatment due to the specific response for a variety of physiological disease environments. However, the deep penetration of engineered PLT in diseased tissues such as tumor is still an important challenge that restricts the therapeutic effect. Herein, the engineered PLT micromotor (PLT@PDA‐DOX) is constructed by a universal self‐polymerization modification method of dopamine, and the chemotherapeutic drug doxorubicin (DOX) is loaded by both π–π stacking interaction with polydopamine (PDA) and cellular endocytosis of PLT. The experimental results prove that PLT@PDA‐DOX can target to tumor site by the specific binding of PLT with cancer cells, and then the secondary PLT‐derived microparticles (PMP@PDA‐DOX) are released with the activation of PLT@PDA‐DOX by tumor microenvironment (TME). Besides, benefiting from the photothermal conversion capability of PDA, PLT@PDA‐DOX micromotors and PMP@PDA‐DOX nanomotors are driven by near‐infrared light to realize deep penetration. And the PLT‐based micro/nanomotors with propulsion capability possess good performance for tumor ablating in vitro and in vivo. In consideration of the operability, mildness, universality of this modification method and the good biocompatibility of PDA, this work may provide a general paradigm for the construction of engineered cells in disease treatment.
Polypyrrole Serving as Multifunctional Surface Modifier for Photoanode Enables Efficient Photoelectrochemical Water Oxidation
Authors: Xu Weiwei , Meng Linxing , Tian Wei , Li Shengnan , Cao Fengren , Li Liang 
Published: November 2021

AbstractConjugated polymer polypyrrole (PPy) with high electrical conductivity and excellent photothermal effect has been adopted as multifunctional surface modifier on ternary metal sulfide (CdIn2S4, CIS) photoanode for photoelectrochemical (PEC) water splitting for the first time. As a p‐type conducting polymer, PPy forms p–n junction with n‐type CIS to relieve the bulk carrier recombination. Besides, the incorporation of Ni ions into PPy matrix further enhances the surface charge carrier transfer at photoanode/electrolyte interfaces. Furthermore, the excellent photothermal effect of PPy produces heat under near‐infrared (NIR) irradiation, which can elevate the temperature of CIS photoanode in situ and further enhance the PEC performance. As a result, the optimum CIS/Ni‐PPy photoanode shows an obviously enhanced photocurrent density of 6.07 mA cm−2 at 1.23 V versus reversible hydrogen electrode under the irradiation of AM 1.5G combined with NIR light, which is the highest among all the CIS based photoanodes reported to date. The synergetic effect of Ni‐PPy significantly suppresses the bulk recombination, decreases the carrier transfer resistance, and accelerates the surface water oxidation dynamics, resulting in high carrier injection efficiency over 80% in the measured potential range. The universality of the multifunctional surface modifier strategy has also been confirmed on metal oxide photoanode.
Integrated 3D Open Network of Interconnected Bismuthene Arrays for Energy‐Efficient and Electrosynthesis‐Assisted Electrocatalytic CO2 Reduction
Authors: He Ying‐Chun , Ma Dong‐Dong , Zhou Sheng‐Hua , Zhang Min , Tian Jian‐Jun , Zhu Qi‐Long 
Published: November 2021

AbstractElectrocatalytic CO2 reduction reaction (CO2RR) toward formate production can be operated under mild conditions with high energy conversion efficiency while migrating the greenhouse effect. Herein, an integrated 3D open network of interconnected bismuthene arrays (3D Bi‐ene‐A/CM) is fabricated via in situ electrochemically topotactic transformation from BiOCOOH nanosheet arrays supported on the copper mesh. The resulted 3D Bi‐ene‐A/CM consists of 2D atomically thin metallic bismuthene (Bi‐ene) in the form of an integrated array superstructure with a 3D interconnected and open network, which harvests the multiple structural advantages of both metallenes and self‐supported electrodes for electrocatalysis. Such distinctive superstructure affords the maximized quantity and availability of the active sites with high intrinsic activity and superior charge and mass transfer capability, endowing the catalyst with good CO2RR performance for stable formate production with high Faradaic efficiency (≈90%) and current density (>300 mA cm−2). Theoretical calculation verifies the superior intermediate stabilization of the dominant Bi plane during CO2RR. Moreover, by further coupling anodic methanol oxidation reaction, an exotic electrolytic system enables highly energy‐efficient and value‐added pair‐electrosynthesis for concurrent formate production at both electrodes, achieving substantially improved electrochemical and economic efficiency and revealing the feasibility for practical implementation.
Silane‐Functionalized Carbon Dots and Their Polymerized Hybrids: From Optoelectronics to Biotherapy
Authors: Dong Xuezhe , Wang Yunfeng , Guan Ruifang , Ren Junkai , Xie Zheng 
Published: November 2021

AbstractNanomaterials usually manifest unique properties in solutions but will be undermined in the solid state. It is necessary to incorporate them into substrates or hybrid them with other functional materials for multiple devices and applications. Though there are a variety of methods to inherit their intrinsic properties like fluorescent and mechanical performance, most nanohybrid materials would lose their transparency irreversibly when construct solid‐state devices. As a hot topic of nanomaterials in recent years, scientific works found a type of carbon dots using silane coupling agents as precursors that can overcome the shortcoming. These carbon dots, called silane‐functionalized carbon dots (SiCDs), are catching increasing interest due to their versatility. Silane coupling agents endow SiCDs with the ability to disperse in solvents or polymerize with matrices by blending or covalent bonds without loss of transparency and decline of performance. The distinguishing features make SiCDs an ideal high transmittance, high doping concentration nanomaterial. The synergistic effect of SiCDs and hybridized sol–gel solid structures can not only hold the optical features of CDs but also enhance their original physical and chemical performance. This highlight focuses on the connection between SiCDs and organosilanes. Plus, preparation methods, applications, and prospective of SiCDs are mentioned.
Water‐Soluble Nanoparticles with Twisted Double [7]Carbohelicene for Lysosome‐Targeted Cancer Photodynamic Therapy
Authors: Zhao Hao , Xu Xiushang , Zhou Long , Hu Yunbin , Huang Yiming , Narita Akimitsu 
Published: November 2021

AbstractHelicene‐based therapeutic agents for organelle‐targeted photodynamic therapy (PDT) involving both type I and II are challenging and still underexplored. Herein, water‐soluble nanoparticles containing twisted double [7]carbohelicene (D7H‐NPs) are prepared through self‐assembly with 1,2‐distearoyl‐sn‐glycero‐3‐phosphoethanolamine‐N‐[methoxy(polyethylene glycol)‐2000] by a nanoprecipitation method. D7H‐NPs display high water solubility with an average size of 46 ± 2 nm. Notably, D7H‐NPs can generate efficient singlet oxygen (1O2) and superoxide anion (O2· −) upon white light irradiation, forming the basis of PDT. Moreover, the typical accumulation in lysosomes of 4T1 cancer cells paves the way to use D7H‐NPs for lysosome‐targeted cancer phototherapeutics. This paper reports a promising helicene‐based phototherapeutic agent involving both type I and II PDT for organelle‐targeted biotherapy.
Recent Progress in the Transfer of Graphene Films and Nanostructures
Authors: Gao Yanjing , Chen Jielin , Chen Guorui , Fan Chunhai , Liu Xiaoguo 
Published: November 2021

AbstractThe one‐atom‐thick graphene has excellent electronic, optical, thermal, and mechanical properties. Currently, chemical vapor deposition (CVD) graphene has received a great deal of attention because it provides access to large‐area and uniform films with high‐quality. This allows the fabrication of graphene based‐electronics, sensors, photonics, and optoelectronics for practical applications. Zero bandgap, however, limits the application of a graphene film as electronic transistor. The most commonly used bottom‐up approaches have achieved efficient tuning of the electronic bandgap by customizing well‐defined graphene nanostructures. The postgrowth transfer of graphene films/nanostructures to a certain substrate is crucial in utilizing graphene in applicable devices. In this review, the basic growth mechanism of CVD graphene is first introduced. Then, recent advances in various transfer methods of as‐grown graphene to target substrates are presented. The fabrication and transfer methods of graphene nanostructures are also provided, and then the transfer‐related applications are summarized. At last, the challenging issues and the potential transfer‐free approaches are discussed.
Constructing STEM identity: An expanded structural model for STEM identity research
Authors: Dou Remy , Cian Heidi 
Published: November 2021

AbstractIdentity development frameworks provide insight into why and to what extent individuals engage in STEM‐related activities. While studies of “STEM identity” often build off previously validated disciplinary and/or science identity frameworks, quantitative analyses of constructs that specifically measure STEM identity and its antecedents are scarce, making it challenging for researchers or practitioners to apply a measurement‐based perspective of participation in opportunities billed as “STEM.” In this study, we tested two expanded structural equation models of STEM identity development, building off extensions of science and disciplinary‐identity frameworks, that incorporated additional factors relevant to identity development: gender, ethnicity, home science support, parental education, and experiencing science talk in the home. Our models test theorized relationships between interest, sense of recognition, performance‐competence, and identity in the context of STEM with undergraduate students (N = 522) enrolled in introductory STEM courses at a Hispanic Serving Institution. Our findings support our measurement of STEM identity and its indicators, providing researchers with a predictive model associated with academic intentions across disciplinary domains in STEM. Further, our expanded model (i.e., Model I+) indicates significant contributions of participant gender, which has a larger indirect effect on STEM identity (β = 0.50) than the direct effect of STEM interest (β = 0.29), and of home support in relation to performance‐competence in academic contexts. Our model also posits a significant contribution of family science talk to sense of recognition as a STEM person, expanding our understandings of the important role of the home environment while challenging prior conceptions of science capital and habitus. We situate our results within a broader discussion regarding the validity of “STEM identity” as a concept and construct in the context of communities often marginalized in STEM fields.