bluuebunny/crossref_metadata_2025_split huggingface dataset:
A scoping review of applied tick control research in North America: funding, implementation, and advancement
Authors: Lehane Áine , Mader Emily M , Poggi Joseph D , McCoy Kaci D , Gruntmeir Jeff , Weldon Caroline T 
Published: December 2024

Abstract
Geographic ranges of ticks and tick-borne pathogens within North America are shifting due to environmental changes and human-driven activities, with species of public health concern presenting a multifaceted risk to human health. Innovative strategies and continued collaboration to control tick populations are needed to combat this growing threat. We conducted a scoping review of the literature to describe the nature of applied tick control research conducted in North America (Canada, Mexico, and the United States) to date, with the goal of describing key concepts and identifying gaps in this research area. A total of 244 articles met our inclusion criteria and were reviewed for patterns in applied tick control authorship and funding, study location, target species, and control methodology. Most studies (83.6%) were conducted exclusively in the United States and 75% focused on ticks of public health concern, principally Amblyomma americanum (Linnaeus, Acari: Ixodidae), Dermacentor variabilis (Say, Acari: Ixodidae), Ixodes scapularis Say (Acari: Ixodidae), and Rhipicephalus sanguineus (Latreille, Acari: Ixodidae). The majority of funding was provided through US federal agencies, predominantly the Centers for Disease Control and Prevention and the United States Department of Agriculture. Ixodes scapularis was the target of over 50% of identified articles, with the majority of research conducted within 3 states in the Northeast region of the U.S. Only 8.2% of included studies evaluated integrated tick management interventions. We note gaps in tick control research regarding (i) non-Ixodes medically relevant tick species, (ii) endemic range coverage, and (iii) control methodologies evaluated.
Effects of salt heterogeneity and competition on the clonal plant Phragmites australis in the wetland of the Yellow River Delta
Authors: Guan Bo , Hu Rong , Wu Mengdi , Wu Qiutang , Yang Jisong , Wang Xuehong , Song Weimin , Han Guangxuan 
Published: December 2024

Abstract
To explore the adaptive strategies of the clonal plant Phragmites australis in salinity-heterogeneous habitats, we conducted a pot control experiment with severing treatment, heterogeneous salt treatment, and competitive treatment using dominant plants from the Yellow River Delta, including P. australis and Suaeda salsa. This study assessed the effects of salinity heterogeneity, clonal integration, and interspecific competition on the morphological and physiological traits of P. australis. The results showed that clonal integration significantly promoted root system growth and underground biomass accumulation of P. australis. Competition significantly reduced plant height, tiller number, leaf number, leaf length, and internode length, inhibiting above- and underground biomass accumulation. Under the heterogeneous salt treatment, clonal integration significantly promoted only the rhizome biomass of P. australis. The S. salsa competition treatment significantly lowered the chlorophyll contents, net photosynthetic rate, stomatal conductance, and transpiration rate of P. australis. Nevertheless, leaf length and width were maintained, potentially to minimize photoinhibition. Competition significantly reduced K+ contents in P. australis fine roots and rhizomes and Na+ contents in fine roots. The Na⁺ content of fine roots was significantly affected by competition, heterogeneous salt treatment, severed treatment, and the interaction between competition and severed treatment. In conclusion, competition significantly inhibited the growth, photosynthesis, and ion content accumulation of P. australis. Meanwhile, clonal integration promoted root growth, especially under heterogeneous saline conditions. Hence, this research provided a significant and deeper understanding of the ecological adaptive responses of clonal plants in coastal heterogeneous habitats.
Hegemony, Hunting and Human Trophies in the East Asian War of 1592–1598
Authors: Clements Rebekah 
Published: December 2024

Abstract
On the eve of his invasion of Korea that launched the Imjin War (1592–8), the Japanese military hegemon, Toyotomi Hideyoshi, held a spectacular hunt parade, the semiotics of which linked the hunting of human and animal trophies. During the war between Japan, Korea and China that followed, Hideyoshi’s troops severed tens of thousands of body parts from combatants and non-combatants, sending heads, ears and noses to Japan for ritual curation alongside hunted animal bodies. In contrast, Chinese and Korean forces took heads and ears from defeated enemies but rarely kept body parts once battlefield tallies were complete. Drawing upon research linking hunting cultures and the taking of human trophies, this difference may be explained by the ascendancy of the warrior class in sixteenth-century Japan, which valued hunting, in contrast to the ambivalent status of hunting within the Chinese and Korean Neo-Confucian elites. Human trophy-taking was an institutionalized practice that, together with the hunting of animals, was intended to assert publicly Hideyoshi’s civilized righteousness and fitness for hegemony. This article makes the case that the human and the more-than-human were entangled in the same regime of violence that characterized and legitimized late sixteenth-century warrior rule in Japan.
Incidence and severity of paediatric sledding injuries during the COVID-19 pandemic
Authors: Alaimo Domenic F , Sharif Nishita T , Carciumaru Redjana , Scott Stephanie C , Kam April J 
Published: December 2024

Abstract

Objectives
During the coronavirus disease 2019 (COVID-19) pandemic, we observed an increase in sledding injuries resulting in paediatric emergency department (PED) visits. We sought to describe the potential impact of the pandemic on the incidence and severity of sledding injuries in children.

Methods
We conducted a descriptive, retrospective cohort study of children with sledding injuries presenting to the PED in a tertiary care centre. We compared injuries occurring before and after the start of the pandemic, using March 11, 2020 as a cut-off. Children aged 0 to 17 years presenting with sledding injuries were eligible for inclusion. We compared monthly visit counts of sledding injuries, demographics, site and type of injury, disposition, surgical intervention, return visits, and length of inpatient admissions.

Results
In total, 243 visits for sledding injuries were analysed. There were 13 presentations in 2018, 31 in 2019, 30 in 2020, 105 in 2021, and 64 in 2022. The mean age was 8.6 years (standard deviation 3.7), with 53.5% of injuries occurring in males. Head injuries and sprains/strains were the most common site and type of injury, respectively (n = 103, 41.4%). There was a significant increase in the number of sledding injuries between pre-COVID-19 and COVID-19 years (P = 0.048). There were no significant differences in demographic and injury characteristics.

Conclusions
We identified a significant increase in PED visits for sledding injuries during the pandemic. Examining epidemiological trends of sledding injuries can facilitate advocacy for improved communication of injury prevention recommendations in the event of future infectious disease outbreaks.
Association of Opioid Use Disorder–Related Service Trajectories during Pregnancy and Postpartum Health Service Use: A Group-Based Multitrajectory Modeling Study
Authors: Fang Yuan , Jeffery Alvin D. , Patrick Stephen W. , Young Jessica , Raffi Edwin , Harder Gabrielle M. , Osmundson Sarah , Phillippi Julia C. , Leech Ashley A. 
Published: December 2024

Objective
The aim of the study was to examine the relationship between opioid use disorder (OUD)-related service trajectories during pregnancy and postpartum emergency department (ED) and hospitalizations.

Methods
We used the Merative MarketScan Commercial Claims and Encounters Database (2013–2021) to identify a cohort of pregnant individuals with OUD. We used group-based multitrajectory modeling to identify opioid-related treatment and service trajectories during pregnancy and examined their association with postpartum ED and hospital utilization.

Results
Seven opioid-related treatment and service trajectories were identified in our cohort of 2,531 pregnant individuals with OUD. Compared to individuals initiating medications for OUD (MOUD) halfway through pregnancy but maintaining high adherence without ancillary services, those receiving only services throughout pregnancy had a higher risk of postpartum ED visits (HRED
= 1.34). This latter group also faced significantly higher risks of postpartum hospitalizations, compared to adherent MOUD use (proportion of days covered ≥80%) alone, both throughout or in the latter half of pregnancy (HRHOS
= 1.93; HRHOS
= 1.60), and patients without MOUD or services (HRHOS
= 1.43). Individuals initiating MOUD late in pregnancy with poor adherence and infrequent service use faced significantly higher risks of postdelivery hospitalization compared to consistent MOUD users throughout pregnancy (HRHOS
= 2.33), or in the latter half, with or without services (HRHOS
= 2.02; HRHOS
= 1.93), and those not receiving MOUD or services (HRHOS
= 1.73).

Conclusions
Adherent MOUD use either throughout pregnancy or the latter half of pregnancy, irrespective of other service use, was associated with better postpartum outcomes defined by fewer ED visits and hospitalizations.
Sodium glucose cotransporter 2 inhibitors improve long-term atrial fibrillation-free survival after catheter ablation.
Authors: Hakgor Aykun , Olgun Fatih Erkam , Dursun Atakan , Kahraman Basak Catalbas , Akhundova Aysel , Savur Umeyir , Besiroglu Mehmet , Kenger Melike Zeynep , Dervis Emir , Sengor Busra Guvendi , Kilicaslan Fethi 
Published: December 2024

Although sodium-glucose cotransporter-2 inhibitors (SGLT2i) are known to reduce the incidence of atrial fibrillation (AF) and AF-related adverse events, evidence on their prognostic effect in patients undergoing catheter ablation (CA) for AF is limited.
In a single-center, 614 patients (mean age 58.1±9.9 years, 42.2% female) who underwent CA for AF were retrospectively divided into 2 groups according to SGLT2i treatment after the index procedure and followed up for 24-months. The primary outcome of the study was AF recurrence following the first 90-day blanking period after CA. Two separate Cox-regression models were constructed to determine the predictors of AF recurrence.
Rates of the primary outcome were 19.4% and 35.7% in the SGLT2i and non-SGLT2i groups, respectively. According to the multivariable Model 1, which was established among the clinically relevant variables that were found to be statistically significant in univariable analysis, left atrial diameter (adjusted HR:1.087, 95% CI:1.054-1.122, p<0.001), SGLT2i therapy (adjusted HR:0.436, 95% CI: 0.286-0.665, p<0.001) and non-paroxysmal AF (adjusted HR:1.549, 95% CI:1.039-2.309, p=0.032) were independent predictors of recurrence after ablation. In Model 2, SGLT2i treatment remained an independent predictor of AF recurrence along with significant variables such as age, heart failure with reduced ejection fraction (HFrEF) and previous stroke (adjusted HR:0.315, 95% CI:0.214-0.461, p<0.001). The favorable efficacy of SGLT2i on the primary outcome was maintained in subgroup analyses.
SGLT2i treatment is associated with lower recurrence after CA for AF in subgroups with and without diabetes or HFrEF and in the overall patient population, independent of AF phenotype.
Longitudinal Changes in Cardiovascular Health Among Young Adults With Overweight and Obesity
Authors: Cuccia Alison F. , DiPietro Loretta , Hayman Laura L. , Whiteley Jessica A. , Napolitano Melissa A. 
Published: December 2024

Background
It is essential to understand factors influencing young adult cardiovascular health (CVH) to reduce morbidity and mortality.

Objective
Evaluate longitudinal changes in CVH among young adults in a weight management intervention.

Methods
Life's Essential 8 (LE8) metrics were calculated for young adults with overweight and obesity enrolled in a randomized controlled trial (n = 459). Outcomes included LE8 total, LE8 behavior, LE8 health, and each LE8 metric. Linear mixed effects models evaluated associations between LE8 and intervention group and demographics and assessed longitudinal changes for 18 months.

Results
Although no composite LE8 scores changed over time, LE8 diet and blood glucose improved. Low socioeconomic status and non-White participants had lower scores for many LE8 metrics when controlling for time. A significant positive intervention effect on LE8 total was observed among those with baseline body mass index <27.5.

Conclusion
Identifying factors associated with LE8 in young adulthood can support CVH, prevent future disease, and minimize health disparities.
Identification of a novel signature related to the immune landscape and prognosis for human colonic adenocarcinoma based on lncRNA pairs
Authors: Wang Ying , Tian Ze-Min , Zhou Zun-Jie , Chen Lang , Zhu Xiao-Feng , Yu Kun , Qiu Yuan 
Published: December 2024

Abstract

Background
Long noncoding RNAs have diverse functions in the immune response to cancer and determining the tumor microenvironment. In consideration of its poor prognosis, immunogenic analysis might be effectively used for predicting the clinical outcome and immunotherapeutic response of colon adenocarcinoma (COAD).

Methods
This study collected expression profiles from 423 COAD cases archived in The Cancer Genome Atlas (TCGA) database, which were then split into four subtypes (C1–C4) according to immune-related long noncoding RNA pairs (IRLPs).

Results
Among these four subtypes, samples of the C4 subtype were associated with the worst prognosis, whereas samples of the C2 subtype were associated with the best prognosis. The analysis of the immune characteristics from samples of different subtypes subsequently showed that the C1 subtype had a significantly higher immune score than the other subtypes, with a higher level of immune cell infiltration, expression of immune-related genes, and a better therapeutic response to programmed cell death 1 (PD-1) inhibitors and cytotoxic T-lymphocyte–associated protein 4 (CTLA4) inhibitors. In addition, a combination of univariate COX analysis, least absolute shrinkage and selection operator (LASSO), Cox regression, and shrinkage estimate was used to successfully construct a prognostic model comprising six IRLPs.

Conclusion
Our research highlights the importance of the IRLP signature in predicting the prognosis and immune characteristics of COAD.
A delayed gastric antral vascular ectasia: A case report and literature review
Authors: Fang Zheke , Zhu Jiajie , Fang Zheng , Hu Qiang , Yang Liangjun 
Published: December 2024

Rationale:
Gastric antral vascular ectasia (GAVE) is a rare cause of gastrointestinal bleeding. It presents challenges in both diagnosis and treatment.

Patient concern:
We reported a female patient who was initially misdiagnosed with hemorrhage of the digestive tract. She was treated with medication for 4 months, but her hemoglobin levels still declined without blood transfusion.

Diagnosis:
Her diagnosis was GAVE after an endoscopic examination.

Interventions:
She was treated with an endoscopic argon plasma coagulation treatment, an endoscopic band ligation treatment, medication, and traditional Chinese medicine.

Outcomes:
This case was followed up for 6 months and her hemoglobin levels were above 9 g/dL.

Lessons:
A combination treatment of endoscopic and medication treatment will be a good choice of GAVE. More comprehensive understanding of GAVE will be build up with the developments of new technologies and methods.
Granulocyte colony-stimulating factor combined with SOFA score for mortality prediction in patients with sepsis
Authors: Fu Xiaomeng , Zhang Ye , Wang Junyu , Liu Yugeng , Wei Bing 
Published: December 2024

Background:
Sepsis in emergency departments is a prevalent occurrence characterized by high hospitalization rate and mortality. The granulocyte colony-stimulating factor (G-CSF) is an indicator for identifying patients with sepsis.

Methods:
A total of 171 patients with sepsis were included in our study who were admitted to the emergency department of Beijing Chaoyang Hospital affiliated with Capital Medical University from October 2020 to April 2021. Out of these patients, 122 did not survive on day 28. Laboratory tests, the sequential organ failure assessment (SOFA) score and the acute physiology and chronic health evaluation II (APACHE II) were calculated. Logistic regression and receiver operating characteristic curve were used to analyze the predictive value of G-CSF for 28-day mortality patients with sepsis.

Results:
There were significant differences in G-CSF, SOFA, APACHE II, systolic blood pressure (SBP), mean arterial pressure, lactate, and albumin between the survivor and non-survivor groups (P < .05). The multivariate regression analysis showed that G-CSF, SOFA, APACHE II, and SBP were independent risk factors for 28-day mortality in patients with sepsis. There was no comparative with significant differences in receiver operating characteristic curves of G-CSF, SOFA, and APACHE II for 28-day mortality in patients with sepsis (Z
1 = 1.381, P = .167; Z
2 = 0.095, P = .924).

Conclusions:
The G-CSF, SOFA, APACHE II, and SBP were identified as independent risk factors for mortality among patients with sepsis. Particularly, G-CSF and SOFA exhibited a high level of predictability for 28-day mortality in this population.
Bipolar sternocleidomastoid partial resection in pediatric patients case report: Technique and early outcomes
Authors: Obana Kyle K. , Myers Annika Y. , Bennett James T. , Siddiqui Ali A. , Fan Bensen B. , Andras Lindsay M. , Wren Tishya A.L. , Skaggs David L. 
Published: December 2024

Rationale:
Congenital muscular torticollis (CMT) that is refractory to conservative therapy is often treated with unipolar or bipolar sternocleidomastoid (SCM) release. Prior texts and descriptions warn of overcorrection or defects, but these have not been encountered in our practice. However, recurrence and undercorrection have been observed, prompting us to transition to a bipolar release with partial resection of SCM. We will review the outcomes of this modified approach.

Patient concerns:
Nine patients (6 males and 3 females) failed a trial of physical therapy and all conservative measures.

Diagnoses:
All patients were diagnosed with CMT refractory to conservative therapy.

Interventions:
Nine patients were treated with unipolar SCM (6 right and 3 left). The mean age at the time of surgery was 9.3±3.4 years.

Outcomes:
There were no surgical complications. No patients required subsequent revision surgery. One patient had prior surgery on the SCM.
At final follow-up, 8 (88.9%) patients had a neutral head position. Rotation in the direction of the release significantly improved from preoperative to final follow-up (from 59.7±26.5 to 85.6±7.3 degrees, P = .01). Rotation in the opposite direction (away from the release) was maintained from preoperative to final follow-up (83.8±11.1 vs. 85.6±8.8 degrees, P = .71). No cases of overcorrection or defect in the area of the resection were observed.

Lessons:
Bipolar release with partial resection may be a promising form of treatment for CMT as head position was improved without overcorrection, defects, or other complications.
COVID-19 induced thrombotic thrombocytopenic purpura in a patient with systemic lupus erythematosus: A rare case report
Authors: Gao Ou , Chen Yinghua , Xie Honglang 
Published: December 2024

Rationale:
Thrombotic thrombocytopenic purpura (TTP) is a severe and rare disease, and its complexity increases in the presence of underlying autoimmune disease and COVID-19 infection, making differential diagnosis and treatment more challenging.

Patient’s concerns:
A 43-year-old patient presented with high fever, intermittent cough, and tea-colored urine.

Diagnoses:
The patient had a long-term history of systemic lupus erythematosus (SLE) and lupus nephritis (LN). The nasopharyngeal swab confirmed the diagnosis of COVID-19 by RT-PCR, and plasma ADAMTS-13 activity was completely deficient (0%). It was considered that COVID-19 infection occurred on the basis of SLE disease and was then complicated with TTP.

Interventions:
The patient was successfully treated with plasma exchange, followed by a combination of biologics and immunosuppressants.

Outcomes:
After 1 year of follow-up, the patient had completely recovered from COVID-19 infection and TTP, meeting the cure criterion. In addition, the LN was in remission, with an SLEDAI-2K score of 0, indicating a low disease activity state.

Lessons:
This article indicates that the patient suffers from both long-standing underlying diseases and the sudden occurrence of SARS-CoV-2 infection, which complicates the determination of the etiology and diagnosis of TTP. Consequently, after thorough analysis of the disease progression, clinical manifestations, laboratory results, and treatment outcomes, it was primarily concluded that COVID-19 was the catalyst for the onset of TTP in this patient.
Gene variant C3 glomerulonephritis with chronic urinary tract infection: A case report and literature review
Authors: Xu Chao , Fan Junfen 
Published: December 2024

Rationale:
C3 glomerulonephritis (C3GN) is 1 type of C3 nephropathy which is a rare glomerular disease associated with abnormal regulation of the alternative complement pathway. This review reports a rare case of C3GN with repeated urinary tract infection and summarizes the clinical features, differential diagnosis, treatment, and outcome of patients with C3GN.

Patient concerns:
A 44-year-old woman was admitted to our hospital because of proteinuria increased for more than 8 years.

Diagnoses:
The patient was finally diagnosed with C3GN by renal biopsy and gene testing.

Interventions:
The patient was worried about the side effects of drugs and strongly refused to use glucocorticoids and immunosuppressants, so she was given angiotensin II receptor blocker monotherapy for glomerulonephritis and quinolones for urinary tract infection.

Outcomes:
Serum creatinine, proteinuria, and serum complement c3 levels remained stable. Our case is still under continuous follow-up.

Lessons:
Clinical diagnosis of C3GN is difficult to make as there are many differential diagnoses, especially post infection nephritis. This case emphasizes the importance of renal biopsy in the diagnosis of C3GN, but the relationship between gram-negative bacilli and C3GN is still unclear. In addition, gene mutation is also involved in the pathogenesis of C3GN, and the treatment of C3GN still needs to be explored.