bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gestão Da Qualidade: A Importância do Método Kanban como Ferramenta Gerencial / Quality Management: The Importance of the Kanban Method as a Management Tool
Authors: Rocha Daniel Pereira , Sousa Josiano César De 
Published: May 2021

Resumo: As instituições têm a cada dia lidado mais com os níveis elevados de concorrência do mercado, onde os clientes tornaram-se mais exigentes quanto a qualidade dos produtos ofertados, exigindo que as empresas adotem ferramentas para enxugar custos e eliminar desperdícios. Diante deste cenário, surge um problema que merece ser estudado: o Kanban pode ser utilizado como ferramenta para enxugar gastos e diminuir desperdícios nos processos de fabricação? Para compreender como estas empresas podem desenvolver processos mais competitivos e se manterem ativas no mercado, o presente artigo tem por objetivo analisar a importância do método Kanban e sua aplicação gerencial dentro das instituições. O mesmo foi desenvolvido utilizando uma abordagem qualitativa, através de uma revisão bibliográfica. Como resultado, foi possível observar que a melhora do desemprenho da instituição pode ocorrer quando os administradores fazem uso da Gestão da Qualidade total, das ferramentas da qualidade, do método Kanban e de recursos como o Just-in-Time, esses recursos contribuem diretamente para a diminuição dos desperdícios, dos volumes de estoques e principalmente para uma redução dos custos das mercadorias. Compreende-se também que estas ferramentas surgiram como uma necessidade para algumas empresas e no período eram consideradas diferenciais competitivos, porém, com o aumento da competitividade elas se tornaram itens essenciais para uma organização eficiente. Torna-se interessante que futuros estudos, direcionados a estas ferramentas, abordem a diversidade de aplicações que podem ser feitas das mesmas, em diferentes ambientes, colhendo assim os resultados dos seus desempenhos. Palavras–Chave: Gestão da qualidade, gesta da qualidade total, o método Kanban
Percepções de Enfermeiros acerca da Depressão em Idosos / Nurses' Perceptions of Depression in the Elderly
Authors: Feitosa Jardenia Pereira , Silva Maria Andressa Bezerra da , Lima Janaine Gonçalves de , Vieira Roberta Peixoto 
Published: May 2021

Resumo: A depressão é uma doença bastante comum na terceira idade, está doença causa inúmeros sintomas que influenciam na qualidade de vida dos idosos. É um transtorno bastante complicado, que se manifesta de vários modos e muitas vezes não é notado pelas pessoas próximas. O estudo tem como objetivo geral: Analisar a percepção de enfermeiros acerca da depressão em idosos. A pesquisa trata-se de uma pesquisa descritiva e exploratória, utilizando método pesquisa de campo com abordagem qualitativa. Está pesquisa foi realizada na cidade de Icó-CE na Estratégia Saúde da Família. Os dados serão coletados através de uma entrevista semiestruturada com 06 Enfermeiros, seguindo o critério de saturação das respostas, no período de novembro de 2020, após aprovação do Comitê de Ética e Pesquisa. A análise de dados será realizada por meio da análise de conteúdo de proposta por Bardin, após as transcrições e codificação das entrevistas atribuindo a inicial do nome de cada enfermeiro. Depois, deverão seguir as frases de análise dos discursos à luz da literatura. Esse estudo obedecerá aos preceitos éticos da resolução 466/12, de 12 de dezembro de 2012 segundo o Conselho Nacional de Saúde, sob o parecer de número 4.385.611. Os dados foram agrupados, organizados e apresentados em forma de categorias. Começando pela a caracterização do profissional, onde pode-se perceber que, a maioria das profissionais possui um perfil de idade mais avançada, com isso contribui para uma maior experiência e vivencias na área, principalmente ao que se refere as enfermeiras das ESFs por possuir um conhecimento satisfatório acerca da depressão na terceira idade, realizando intervenções para promover bem-estar aos pacientes. Palavras-chave: Cuidados de Enfermagem; Depressão; Saúde do idoso; Envelhecimento.
O Direito à Água e sua Proteção Jurídica: Desafios do Direito Ambiental na Contemporaneidade / The Right to Water and its Legal Protection: Environmental Law Challenges in Contemporary
Authors: Moreira Marilia Lima , Miguel Joelson Rodrigues , Matos Raimundo Giovanni França 
Published: May 2021

Resumo: literatura tem apresentado diversos modelos de gestão dos recursos hídricos, diferenciando-os em função das características políticas, econômicas, sociais, econômicas e culturais da região considerada para sua aplicação. Porém, existe a necessidade de entender que devemos considerar independente de que características e peculiaridades existam nas diferentes regiões do planeta, premissas consensuais em qualquer modelo que adote, pois passa a reconhecer a natureza sistêmica do ciclo hidrológico e a necessidade de incorporar uma abordagem sustentável dos recursos hídricos e meio ambiente. Este artigo desenvolverá uma abordagem de gestão que considera estes pressupostos como fundamentais na consecução de um modelo de gestão para os recursos hídricos tomando a si a experiência brasileira, para embasar o desenvolvimento de políticas públicas para gestão e possível racionamento de água, sem prejudicar a população, enfatizando seus direitos civis e constitucionais. Como também conscientizar a população que a água é um bem finito que deve ser preservado não só pelo Poder Público como por cada um de nós para que assim possamos ter esse bem por muito mais tempo e até mesmo pensando nas gerações futuras que também precisaram desse bem para sobreviver.
lncRNA myocardial infarction-associated transcript (MIAT) knockdown alleviates LPS-induced chondrocytes inflammatory injury via regulating miR-488-3p/sex determining region Y-related HMG-box 11 (SOX11) axis
Authors: Pan Weiwei , Wang Haibao , Ruan Jianwei , Zheng Wenbiao , Chen Fanghu , Kong Jinsong , Wang Yong 
Published: May 2021

Abstract
Long noncoding RNA (lncRNA) has been shown to be involved in the development of osteoarthritis (OA), an age-related bone and joint disease. However, the function and possible molecular mechanism of lncRNA myocardial infarction-associated transcript (MIAT) in lipopolysaccharide (LPS)-induced chondrocytes injury model remain unexplored. Cell viability and apoptosis were detected by methyl thiazolyl tetrazolium (MTT) and flow cytometry, respectively. Western blot was used to detect protein expression. The concentrations of inflammatory factors were estimated by enzyme-linked immunosorbent assay (ELISA). Abundances of MIAT, microRNA-488-3p (miR-488-3p), and sex determining region Y-related HMG-box 11 (SOX11) were examined by quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). Dual-luciferase reporter and RNA immunoprecipitation (RIP) assays were performed to analyze the interaction between miR-488-3p and MIAT or SOX11. LPS caused chondrocytes injury by reducing cell activity and increasing apoptosis rate and inflammatory factor secretions. Higher levels of MIAT and SOX11 and lower miR-488-3p were observed in LPS-treated C28/I2 cells. Importantly, knockdown of MIAT attenuated the LPS-induced cell injury by targeting miR-488-3p, and miR-488-3p overexpression weakened the LPS-induced cell injury by targeting SOX11. Additionally, repression of MIAT inactivated the LPS-induced NF-κB signaling pathway by decreasing SOX11 and increasing miR-488-3p. Knockdown of MIAT alleviated the LPS-induced chondrocytes injury by inhibiting the NF-κB signaling pathway mediated by the miR-488-3p/SOX11 axis.
Mixed gel electrolytes: Synthesis, characterization, and gas release on PbSb electrode
Authors: Thi Binh Phan , Thi Van Anh Nguyen , Thi Thanh Thuy Mai , Thi Xuan Mai , Duyen Nguyen The , Thi Chuyen Vi , Quy Bui Minh 
Published: May 2021

Abstract
Mixed gel electrolytes were fabricated chemically at a temperature range of 2–5°C using some additives comparing with traditional electrolytes (1.26 g/cm3 H2SO4). The polyacrylamide (PAM) content is kept constant (0.2 wt%), while the propylene glycol (PPG) and nano fumed silica (NFS) contents varied. The material characteristics of samples were assessed by physical appearance observation, electrochemical measurements, and physicochemical methods. The results showed that a hard gel without separation of solutions was found in the case using a PAM/PPG/NFS ternary additive (0.2/0.1/0.6 wt%). The morphological structure (<50 nm) of mixed gel electrolytes was in the range of nanometer. The gas release on the PbSb electrode was strongly inhibited (92.2–93.7% for O2 and ∼55% for H2 at the 120th cycle), which will both contributes to reducing the pressure as well as limiting water loss in the sealed lead acid battery, compared with that in the sulfuric acid medium.
In vitro chemotherapeutic and antiangiogenic properties of cardenolides from Acokanthera oblongifolia (Hochst.) Codd
Authors: Soltan Maha M. , Abd-Alla Howaida I. , Hassan Amal Z. , Hanna Atef G. 
Published: May 2021

Abstract
Acovenoside A (Acov-A) and acobioside A (Acob-A) were isolated from Acokanthera oblongifolia. Their anticancer properties were explored regarding, antiproliferative and antiangiogenic activities. The study included screening phase against six cancer cell lines followed by mechanistic investigation against HepG2 cancer cell line. The sulforhodamine-B (SRB) was used to determine their growth inhibitory power. In the other hand, flow cytometry techniques were recorded the cell death type and cell cycle analysis. The clonogenic (colony formation) and wound healing assays, enzyme-linked immunosorbent assay (ELISA) and molecular docking, were performed to evaluate the antiangiogenesis capability. Both compounds were strongly, inhibited four cancer cell lines at GI50 less than 100 nM. The in vitro mechanistic investigation against HepG2 resulted in cell accumulations at G2M phase and induction of apoptosis upon treating cells separately, with 400 nM Acov-A and 200 nM Acob-A. Interestingly, the same concentrations were able to activate caspase-3 by 7.2 and 4.8-fold, respectively. Suppressing the clonogenic capacity of HepG2 cells (20 and 40 nM) and inhibiting the migration of the colon Caco-2 cancer cells were provoke the results of vascular endothelial growth factor receptor2 (VEGFR2) kinase enzyme inactivation. The docked study was highly supportive, to the antiangiogenic approach of both cardenolides. The isolated cardenolides could orchestrate pivotal events in fighting cancer.
Cyclin D1 controls development of cerebellar granule cell progenitors through phosphorylation and stabilization of ATOH1
Authors: Miyashita Satoshi , Owa Tomoo , Seto Yusuke , Yamashita Mariko , Aida Shogo , Sone Masaki , Ichijo Kentaro , Nishioka Tomoki , Kaibuchi Kozo , Kawaguchi Yoshiya , Taya Shinichiro , Hoshino Mikio 
Published: May 2021

AbstractDuring development, neural progenitors are in proliferative and immature states; however, the molecular machinery that cooperatively controls both states remains elusive. Here, we report that cyclin D1 (CCND1) directly regulates both proliferative and immature states of cerebellar granule cell progenitors (GCPs). CCND1 not only accelerates cell cycle but also upregulates ATOH1 protein, an essential transcription factor that maintains GCPs in an immature state. In cooperation with CDK4, CCND1 directly phosphorylates S309 of ATOH1, which inhibits additional phosphorylation at S328 and consequently prevents S328 phosphorylation‐dependent ATOH1 degradation. Additionally, PROX1 downregulates Ccnd1 expression by histone deacetylation of Ccnd1 promoter in GCPs, leading to cell cycle exit and differentiation. Moreover, WNT signaling upregulates PROX1 expression in GCPs. These findings suggest that WNT‐PROX1‐CCND1‐ATOH1 signaling cascade cooperatively controls proliferative and immature states of GCPs. We revealed that the expression and phosphorylation levels of these molecules dynamically change during cerebellar development, which are suggested to determine appropriate differentiation rates from GCPs to GCs at distinct developmental stages. This study contributes to understanding the regulatory mechanism of GCPs as well as neural progenitors.
Peran Badan Wakaf Indonesia Pasca Terbitnya Undang-Undang Nomor 41 Tahun 2004 Tentang Wakaf
Authors: Hendrik Mohamad , Mufidah Mufidah 
Published: May 2021

Undang-Undang Nomor 41 Tahun 2004 tentang Wakaf membangun paradigma baru tentang tata kelola Wakaf di Indonesia. Wakaf yang semula dikelola dengan cara sederhana dan kekeluargaan karena merupakan ajaran dalam hukum Islam yang tumbuh menjadi bagian dari tradisi yang hidup dalam masyarakat, kini bertransformasi dalam bentuk tata kelola lembaga, yang memiliki kredibelitas, profesionalitas dan efesien. Tata kelola Wakaf melalui badan Wakaf terbukti secara efesien meningkatkan kesejahteraan masyarakat. Bahkan melalui tata kelola instrumen pengelolaan Wakaf tidak hanya sebagaimana tujuan peningkatan dana abadi, lebih dari itu Wakaf kini dapat dijadikan sebagai sumber kekuatan pemberdayaan perekonomian yang potensial untuk mewujudkan kesejahteraan umat. Hal ini tidak terlepas dari peran Undang-undang Nomor 41 Tahun 2004 Tentang Wakaf yang membangun Wakaf di Indonesia lebih profesional dan lebih bermanfaat. Untuk mengkaji Wakaf leih dalam lagi Penulis merumuskan permasalahan sebagai berikut, 1. Apa peranan Badan Wakaf Indonesia terhadap pelaksanaan Wakaf di Indonesia? Dan 2. Bagaimana sistem pengelolaan Wakaf sebelum dan sesuadah Undang-undang Nomor 41 Tahun 2004 tentang Wakaf?, adapun tujuan penelitian ini adalah 1. Untuk mengetahui peran Badan Wakaf Indonesia terhadap pelaksanaan Wakaf di Indonesia dan 2. Untuk mengetahui sistem pengelolaan Wakaf sebelum dan sesudah adanya Undang-Undang Nomor 41 Tahun 2004 tentang Wakaf. Dalam melakukan penelitian, Peneliti memilih metode library research (Penelitian Kepustakaan) dengan pendekatan yuridis normatif dan historis. Menggunakan sumber hukum primer peraturan perundang-undangan Nomor 41 Tahun 2004 tentang Wakaf diperkuat dengan sumber hukum sekunder dari buku, jurnal hukum dan internet serta doktrin-doktrin hukum, penelitian ini disajikan dengan tekhnik deskriptif analitis, yakni menyajikan dengan cara menganalisa. Dari penelitian ini, Penulis menyimpulkan sebagai berikut 1. Bahwa Badan Wakaf Indonesia memiliki peranan dalam membangun tata kelola pelaksanaan Wakaf di Indonesia baik dalam menyelenggarakan administrasi maupun pengelolaan secara nasional yakni membina para nazhir 2. Bahwa sistem pengelolaan Wakaf memiliki perbedaan yang sangat signifikan antara sebelum dan sesudah diterbitkan Undang-Undang Nomor 41 Tahun 2004 tentang Wakaf, untuk itu Undang-undang Nomor 41 Tahun 2004 memiliki peranan yang sangat penting dalam membangun tata kelola Wakaf lebih baik.Kata Kunci : Wakaf, Badan Wakaf Indonesia, Undang-Undang Nomor 41 Tahun 2004 Tentang Wakaf
SPECIES OF THE GENUS ADIALYTUS (HYMENOPTERA, BRACONIDAE: APHIDINAE) IN THE FAUNA OF UKRAINE
Authors: Kaliuzhna M. O. 
Published: May 2021

Genus Adialytus is represented in Europe by four species, only two of which are recorded in the fauna of Ukraine: Adialytus ambiguus (Haliday, 1834) and Adialytus salicaphis (Fitch, 1855). Data on the distribution of these species, their trophic specialization, and habitat associations are provided on the basis of material from the collection of I. I. Schmalhausen Institute of Zoology of the National Academy of Sciences of Ukraine (SIZK) and previous publications. A. ambiguus is a broad oligophagous, however, parasitizing mostly species of the genus Sipha on Poaceae. In Ukraine, A. ambiguus is found in the Forest-Steppe zone (Kyiv, Cherkasy, Kirovohrad, Poltava regions), in the Zone of broad-leaved forests of Ukraine (Ternopil region). Adialytus salicaphis is registered for now only in the Zone of mixed forests of Ukraine (Kyiv region). This species is a narrow oligophagous and develops on aphids of the genus Chaitophorus on Salix and Populus. Its potential areal might include also Forest-Steppe zone (more probably on the Left Bank of Dnieper River) and plains of big rivers in the Steppe zone of Ukraine. The potential role of these species as biocontrol agents is discussed: A. ambiguus could be recommended for consideration as a new candidate for biocontrol of Sipha spp. and probably Rhopalosiphum spp, on cereal crops in Ukraine, while A. salicaphis is not a species of practical importance in the country now. We consider quite probable finding in Ukraine another well-distributed European species A. thelaxis (Starý, 1961), which is a parasitoid of aphids of the genus Thelaxes on oaks.
<em>Desde el Abya Yala hasta Kurdistán</em>. Conciencia opositiva diferencial y articulaciones feministas disidentes descolonizadoras y despatriarcalizadoras
Authors: Maritano Ornella 
Published: May 2021

Este artículo analiza el evento denominado plaza de Abya Yala, realizado en el marco del 34° Encuentro Nacional de Mujeres, en la ciudad de La Plata, Argentina en 2019. El análisis se basa en el marco teórico de la descolonialidad y en la crítica planteada por las feministas latinoamericanas a la noción de interseccionalidad. A partir de las características más sobresalientes de dicha actividad –que congregó gran cantidad de corporalidades y subjetividades feminizadas y disidentes– se recuperan las principales enunciaciones que allí tuvieron lugar. Este evento es analizado como una forma de articulación entre los feminismos de carácter plurinacional, indígenas populares y los feminismos disidentes en clave de coalición feminista disidente despatriarcalizadora y descolonizadora. El estudio concluye que la plaza de Abya Yala constituyó el escenario político para el surgimiento de una conciencia crítica de carácter translocal/global feminista disidente, descolonizadora y despatriarcalizadora.
Outline of a theory of non-translation
Authors: Glynn Dominic 
Published: May 2021

AbstractNon-translation has not been adequately theorised despite its relevance to conceptualising how texts circulate across linguistic and cultural borders. This article outlines a theory which defines non-translation in three ways: first, in terms of systemic resistance to translation; second, as a set of procedures forming part of an overarching translation strategy; third, as the result of discourse that conceals the process of translation for various purposes. It describes the characteristics of ideological, economic, and poetological resistance to translation, categorising environments as hostile or hospitable depending on the extent to which translation is prevented from happening. Moving beyond a binary opposition between translation and its negative, the article then considers how partial non-translation might be used as a procedure to facilitate the translation of the rest of a text. Finally, the ways in which translational actions are concealed or negated, and thus rendered non-translations, are examined. The overarching aim of the article is to contribute a workable theory of non-translation that will serve as the basis for future studies of translation as a practice, process and product.
A self-efficacy scale for measuring student progress in translation company simulations
Authors: Konttinen Kalle 
Published: May 2021

AbstractApplying factor analysis on survey data, this paper develops a concise scale of translation service provision self-efficacy aimed for diagnosing learning needs and assessing progress in pedagogical translation company simulations. First, a model of translation service provision activities based on the translation service provision standard ISO 17100 and a business process model of translation service is constructed and operationalized as a draft scale. The draft scale is then tested in an international survey (n = 380) conducted in connection with translation company simulation courses in university-level translator education. Exploratory factor analysis is used to identify dimensions and adequate items for a concise scale that comprises two four-item subscales: a project management self-efficacy subscale and a translation-production self-efficacy subscale. The scale is validated through confirmatory factor analysis. It is expected to be useful as a light-weight measurement instrument for frequent testing or as a compact part of more extensive scales.
Investigating usability in postediting neural machine translation: Evidence from translation trainees' self-perception and performance
Authors: Wang Xiangling , Wang Tingting , Muñoz Martín Ricardo , Jia Yanfang 
Published: May 2021

AbstractThis is a report on an empirical study on the usability for translation trainees of neural machine translation systems when post-editing (mtpe). Sixty Chinese translation trainees completed a questionnaire on their perceptions of mtpe's usability. Fifty of them later performed both a post-editing task and a regular translation task, designed to examine mtpe's usability by comparing their performance in terms of text processing speed, effort, and translation quality. Contrasting data collected by the questionnaire, keylogging, eyetracking and retrospective reports we found that, compared with regular, unaided translation, mtpe's usefulness in performance was remarkable: (1) it increased translation trainees' text processing speed and also improved their translation quality; (2) mtpe's ease of use in performance was partly proved in that it significantly reduced informants' effort as measured by (a) fixation duration and fixation counts; (b) total task time; and (c) the number of insertion keystrokes and total keystrokes. However, (3) translation trainees generally perceived mtpe to be useful to increase productivity, but they were skeptical about its use to improve quality. They were neutral towards the ease of use of mtpe.
Relationship between metabolic syndrome and vitamin D level in patients with ankylosing spondylitis
Authors: AKALTUN Mazlum Serdar , ALTINDAĞ Özlem , TURAN Neytullah , AYDENİZ Ali , GÜRSOY Savaş , GÜR Ali 
Published: May 2021

Purpose: The purpose of this study is to reveal the relationship between the level of Vitamin D and the development of Metabolic Syndrome (MetS) in patients with Ankylosing Spondylitis (AS).
Materials and Methods: 67 AS patients were included in this cross-sectional descriptive study. Socio-demographic data, waist circumference and systolic blood pressure were evaluated. Fasting blood glucose, HDL cholesterol, Triglyceride and Vitamin D values were recorded. Diagnosis of MetS was made according to National Cholesterol Education Program’s Adult Treatment Panel (NCEP/ATP III). Disease activity and quality of life were assessed.
Results: In the present study, a significantly negative correlation was detected between Vitamin D levels and MetS in AS patients. HDL levels and Vitamin D levels were significantly lower in patients with MetS. Multiregression analysis showed that MetS was positively associated with BMI, Triglyceride level, fasting glucose and negatively associated with HDL cholesterol and Vitamin D.
Conclusion: This study shows that vitamin D may have a role in the development of MetS in patients with AS. However, more studies are needed to explain the relationship between vitamin D and metabolic syndrome in patients with ankylosing spondylitis.