bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the influence of parents’ home reading practices on emergent literacy
Authors: Strauss Annaly M. , Bipath Keshni 
Published: March 2021

The purpose of this article is to explore the correlation between Namibian preprimary and Grade 1 parents’ demographic characteristics and print and digital reading practices in home environments. A quasi-experimental descriptive research design wasselected to launch this investigation in the Khomas region. Survey data documented the relationship between parents’ demographic variables and print and digital reading behaviours. The study tested the null-hypothesis (Hₒ: u1 = u2) and non-directional hypothesis (Hₒ: X1 ≠X2). The underlying assumption is that parents home reading practices positively impact children’s early language and literacy development. The findings reveal that there is no significant relationship between age, gender, education, family size, and employmentstatus, with print and digital reading behaviours that influence children’s emergent language and literacy development in home environments. In a Chi-Square test, the null hypothesis was rejected for age, gender, education, family size, and employment status, but retained and positively correlated to marital status, child reading behaviour, and parents’ book, magazine and newspaper reading behaviour. The implication is that when parents buy print materials for home reading purposes and engage their children in pleasurable reading experiences, their children are more likely to be supported at home to influence favourable language and literacy outcomes in school. The study contributes to family literacy literature and highlights the relationship between parents’ reading behaviours and children’s emergent language and literacy development.
Keywords: emergent literacy, home environment, parents, print and digital reading, reading behaviours, socioeconomic status
ARABIC: أهمية العلوم المعاصرة وفوائدها في فهم دراسات الحديث وعلومه
Authors: Muhammad Ghani Dr. Muhammad Anwar , Dr. Farzana Iqbal  
Published: March 2021

The modern sciences and technology have important role in today’s life and development of society. And it is a significant driver behind change, and sometimes plays an important role in renovations in educational design and delivery. As all the Sciences are contributory and linked to each other, so there is immense possibility to use the modern sciences in the service of Hadith and its sciences. his research is to elaborate the importance and benefits of modern sciences in understanding Hadith and its sciences. And also give an Islamic perspective on the modern sciences.
Prevalencia de esteatosis hepática no alcohólica en personas diabéticas tipo 2
Authors: Murray Adriana Laclé , Chaverri Marco Esquivel , López Mauricio Madrigal , Chacón Carlos Alpízar 
Published: March 2021

la esteatosis hepática no alcohólica es la causa más común de enfermedad hepática crónica y existe cada vez mayor evidencia de que progresa a cirrosis, falla hepática y carcinoma hepatocelular. Esta condición es muy frecuente en las personas diabéticas, y siendo la diabetes una enfermedad crónica de alta prevalencia en la población costarricense (10,8% en adultos), y que genera un alto impacto negativo en el Sistema de Salud y en su mortalidad, se consideró oportuno conocer la prevalencia de la esteatosis hepática no alcohólica (incluyendo la esteatohepatitis) en esta población específica.
Listas de Espera
Authors: Navarro Andrea Monge , Sancho Gabriela Murillo , Céspedes Alejandro Calderón , Araya Andrea Vega , Cubillo Ariadna Aguilar 
Published: March 2021

Las listas de espera en la CCSS pueden convertirse en una verdadera problemática, en la medida en que no sea atendida. Resulta importante ofrecer alternativas con base en los resultados del análisis de diversas experiencias y modelos.
Bacteriemia por Kluyvera cryocrescens
Authors: Acuña Ronny Muñoz , Rodríguez Juan Diego Méndez , Vindas Juan Villalobos 
Published: March 2021

La Kluyvera cryocrescens es una enterobacteria gram negativa que se ha aislado del esputo, orina, secreción biliar, líquido peritoneal y sangre en los seres humanos, raramente es causa de infección clínicamente significativa. Sin embargo hay varios casos descritos en la bibliografía, donde se ha manifestado con cuadros de sepsis severa y choque séptico, algunos con adecuada respuesta a diferentes terapias antibióticas. Se presenta un caso de sepsis severa, debido a bacteriemia por Kluyvera cryocrescens, en un masculino de 73 años, y se describe su diagnóstico, tratamiento y evolución. El paciente desarrolló la infección durante su estadía hospitalaria y recibió tratamiento 10 días con cefalosporinas de tercera generación, logrando una adecuada resolución de su cuadro.
Cor Triatriatum sinester
Authors: Chaves Daniel Quesada , Navas Andrés-Francisco Garzona , Navas Gloriana-María Garzona 
Published: March 2021

El cor triatriatum sinester es una anormalidad cardiaca congénita poco frecuente, que constituye del 0,1 al 0,4% de todas las malformaciones cardiacas. Se caracteriza por una división anómala de la aurícula izquierda por una membrana fibromuscular, la cual genera dos cavidades que se comunican por uno o más orificios con distinto grado de obstrucción. Se asocia con otras anomalías cardiacas, principalmente con comunicación interauricular. Se puede presentar en la infancia, cuando suele ser fatal, o más tardíamente en el adulto, como insuficiencia cardiaca, o incluso cursar de forma asintomática, dependiendo del tamaño de los orificios y del gradiente de presión entre las cavidades. En este artículo se presenta el caso de un masculino de 30 años, sin patologías crónicas, quien consulta por disnea de grandes esfuerzos en los últimos 6 meses, a quien se le diagnostica por medio del ecocardiograma transtorácico y transesofágico un cor triatriatum sinister.
Hidroxicloroquina: Del fármaco de herencia Inca hasta la inmunología moderna
Authors: Alfaro Murillo Alberto , León Bratti María Paz 
Published: March 2021

La hidroxicloroquina es un antiguo fármaco proveniente del árbol de quino (Cinchona pubescens), a partir del componente químico alcaloide llamado quinina. Sus primeros usos se documentaron en el Imperio Inca del Perú. Se caracteriza por distintos efectos beneficiosos en enfermedades inmunológicas, al disminuir los procesos de autoinflamación y autoinmunidad persistente.
Esta revisión se enfoca en describir los mecanismos inmunomoduladores de la hidroxicloroquina, así como los efectos del fármaco en algunas de las enfermedades autoinmunes más prevalentes: lupus eritematoso sistémico, artritis reumatoide, síndrome de Sjögren, vasculitis sistémicas, nefropatía por IgA, síndrome antifosfolípido, distintas enfermedades inmunológicas de la piel. También se revisarán los efectos adversos descritos para este fármaco, especialmente la toxicidad de retina, que es el más temido.
Descriptores: hidroxicloroquina, quinina, autoinmunidad, receptores Toll-Like, enfermedades de la retina.
Rituximab for the Treatment of Neuromyelitis Optica Spectrum Disorder
Authors: Banerjee Srabani , Butcher Robyn 
Published: March 2021

Four systematic reviews, 1 randomized controlled trial (RCT), 1 economic evaluation, and 2 evidence-based guidelines were identified.
Four systematic reviews (2 that included moderate- to high-quality evidence and 2 that did not report the quality of the evidence) and 1 RCT (that provided high-quality evidence) reported on the clinical effectiveness of rituximab (RTX) for the treatment of neuromyelitis optica spectrum disorder (NMOSD). Overall, RTX treatment appeared to reduce the relapse rate and disability level compared with pre-treatment or placebo. In terms of reduction in relapse rate and disability, RTX was either better or not different from azathioprine (AZA). For relapse rates, disability levels, and incidence of adverse events, network meta-analyses showed that no treatment was favoured for comparisons between RTX, mycophenolate mofetil (MMF), and cyclophosphamide (CYP).
One economic evaluation (of moderate quality) showed that, for patients with NMOSD, in the context of the Thai health care system, RTX biosimilar with CD27+ memory B cell monitoring regimen had the highest probability (48%) of being cost-effective, followed by AZA (30%), MMF (13%), RTX with CD27+ memory B cell monitoring regimen (9%), RTX biosimilar (0%), and RTX (0%) at a willingness-to-pay threshold of 160,000 Thai bhat (equivalent to US$5,289 in 2019 values) per quality-adjusted life-year gained.
The 2 guidelines recommended immunosuppressants (RTX, AZA, and MMF) for prevention of NMOSD attacks. In addition, 1 guideline mentioned that tocilizumab, eculizumab, inebilizumab, and satralizumab can be used in NMOSD leave it up to patients who have no response to other immunosuppressants. The quality of the evidence that informed the guidelines and the strength of the recommendations were not reported.
Findings need to be interpreted with caution given the limited quantity of evidence on comparative efficacy and safety between various immunosuppressants, that many of the included primary studies were retrospective studies, the heterogeneity among the studies included in the systematic reviews, and the lack of clarity with respect to the strength of the recommendations.
Faktor-Faktor Yang Berhubungan dengan Kepatuhan Petugas Cleaning Service dalam Penggunaan Alat Pelindung Diri (APD) di BLUD RSUD Kota Langsa Tahun 2019
Authors: Handayani Vivi , Nahrisah Putri 
Published: March 2021

Rumah sakit merupakan tempat kerja yang memiliki resiko tinggi terhadap keselamatan dan kesehatan sumber daya manusia rumah sakit, pasien, pendamping pasien, pengunjung, maupun lingkungan rumah sakit.Berdasarkan laporan kasus kecelakaan kerja dari badan pelaksana Jaminan Sosial (BPJS) Ketenagakerjaan, hingga akhir tahun 2015 jumlah kecelakaan kerja yaitu 110.285 kasus, sedangkan tahun 2016 berjumlah 105.182 kasus, sehingga mengalami penurunan sebanyak 4,6%. Sedangkan sampai Bulan Agustus tahun 2017 terdapat 80.392 kasus. Jenis penelitian ini bersifat analitik dengan desain cross sectional study dengan variabel sebab dan akibat yang terjadi pada objek penelitian diukur dan dikumpul dalam waktu yang bersamaan.Dengan total sampel 60 responden. Hasil penelitian ini menunjukkan ada hubungan antara pengetahuan dengan kepatuhan penggunaan APD pada petugas cleaning service di BLUD RSUD Kota Langsa .Diperoleh nilai P-Value = 0,014 (p<0,05), ada hubungan pengawasan dengan kepatuhan penggunaan APD pada petugas cleaning service di BLUD RSUD Kota Langsa. Didiperoleh nilai P-Value = 0,007 (p<0,05), ada hubungan Sikap dengan kepatuhan penggunaan APD pada petugas cleaning service di BLUD RSUD Kota Langsa. Diperoleh nilai P-Value= 0,007 (p<0,05).
Reconstruyendo el conocimiento práctico en confinamiento. Una experiencia de enseñanza en la formación inicial de docentes.
Authors: Soto Gómez Encarnación , Maldonado-Ruiz Gonzalo , Márquez-Román Ana , Peña Trapero Noemí 
Published: March 2021

Este artículo presenta la experiencia y los dilemas de enseñanza de un grupo de docentes en la formación inicial de profesorado del Grado en Educación Infantil, en su adaptación a la virtualidad ocasionada por la COVID-19. Un proyecto que, con 10 años de andadura, ofrece una oportunidad para repensar la formación inicial en el marco del confinamiento. Inicialmente se describe el complejo e incierto contexto social actual y los retos ineludibles para la formación inicial del profesorado: la reconstrucción del conocimiento práctico de nuestras estudiantes y el diseño de un habitus vivencial y crítico como sostén de los principios pedagógicos de la experiencia que describimos en la segunda parte. Un triángulo didáctico en relación permanente con las reflexiones de las estudiantes y los debates e inquietudes que como docentes hemos compartido en los espacios de coordinación y adaptación a la virtualidad. Las conclusiones de esta experiencia sitúan la coordinación y la tutorización como ejes relevantes, al mismo tiempo en el que se advierten las dificultades e imposibilidad de que una experiencia de formación inicial de docentes íntegramente virtual -sin una práctica en relación y presencia de los niños y niñas- facilite la reconstrucción del conocimiento práctico de maestras y maestros de Educación Infantil.
This article presents the experience and teaching dilemmas of a group of teachers in the Initial Early Childhood Teachers’ Training, in their adaptation to the virtuality caused by COVID-19. A 10-year-old project that offers an opportunity to rethink Initial Teacher Training in confinement. Initially, the complex and uncertain current social context and the inescapable challenges for Initial Teacher Training are described: the reconstruction of the practical knowledge of our students and the design of an experiential and critical habitus as support for the pedagogical principles of the experience that we describe in the second part. A didactic triangle in permanent relationship with the students’ reflections and the debates and concerns that we, as teachers, have shared in the spaces of coordination and adaptation to virtuality. The conclusions of this experience place coordination and tutoring as relevant axes. At the same time, the difficulties and impossibility of a fully virtual Initial Teacher Training experience facilitating the reconstruction of the practical knowledge of Early Childhood Education teachers without a practice in relation to children are noted.
Change at the Museum - The Knowledge Production of Human Evolution
Authors: Ceder Simon 
Published: March 2021

Museums today play an important role as a space for learning about science and the world. For this article, the phenomenon of human evolution is explored as an example of knowledge production about change. Empirical materials on exhibitions of human evolution were collected from visits to 25 historical and natural history museums.
The empirical materials are analyzed together with a posthuman version of evolutionary theory, with a focus on aspects of change. This is based on a post-anthropocentric and relational approach to human evolution and change. The analysis shows that (i) museums face an anthropocentric tension, (ii) evolutionary change is seen as both an inherent quality of the individual species and as an entanglement of humans and the natural environment, (iii) the notion of ‘the first human’ produces various and contentious versions of knowledges about evolutionary change.
Comparative Analysis of the Nutritive Value of Smoked, Dried Procambarus clarkii (Freshwater Crayfish) from Three Nigerian States
Authors: Omole Oluwafemi Akinsola , Adepoju Oluwafunmike Blessing , Moradeyo Oluwasola Toluwalope , Okuneye Olayinka Josephine , Bello Adunola Abosede 
Published: March 2021

The nutritive value of smoked, dried Procambarus clarkii sourced from Akwa Ibom, Rivers and Lagos states of Nigeria were evaluated and compared. The proximate composition of the crayfish samples were determined using official methods of analysis, mineral composition were determined using Atomic Absorption Spectrophotometer and the amino acid composition were analysed using Amino Acid Analyser. The proximate composition of the crayfish samples from three different locations (Akwa Ibom, Lagos and Rivers states) such as moisture, crude protein, crude fat and ash contents showed significant difference (p<0.05) across the selected locations while crude fibre and carbohydrate content showed no significant difference (p<0.05) across the selected locations. The amino acids composition gave the crayfish sample from Akwa Ibom state as the richest source of essential amino acids. The mineral contents of the crayfish samples such as potassium, phosphorus, magnesium, manganese and calcium showed significant difference (p<0.05) across the selected locations while calcium, zinc and sodium contents showed no significant difference (p<0.05) across the selected locations. Comparing their nutrient component, smoked, dried P. Clarkia from Awka Ibom state possess the richest nutritive value.
Hepato-Renal-Curative Effect of the Herbal Supplement of Aloe vera Linn Gel versus Moringa oleifera on Acetaminophen-Induced Damage on the Liver and Kidney of Wistar Rats (Rattus novergicus)
Authors: Abaekwume Chukwunyere Ogechi , Kagbo Hope Delesi 
Published: March 2021

Background: Acetaminophen (APAP, paracetamol) is the most frequently used over-the counter analgesic and antipyretic drug. Conversely, its overdose leads to both liver and kidney damage. Several scientific reports have focused majorly on protective effects of medicinal plants on APAP –induced hepato-renal-toxicity. actually, there is a dearth of work on the hepato-renal-curative effects of the herbal drugs supplements on APAP induced toxicity.
Aims: In the present study, Aloe vera (ALOV) gel versus Moringa oleifera (MORN) leaf supplement effects was evaluated curatively against Acetaminophen (APAP) induced hepato- renal-toxicity.
Study Design: This study was an experimental study in the Animal House of the Department of Pharmacology University of Port Harcourt. The work lasted for 7 days.
Methodology: Twenty adult wistar rats weighing 185-220 g were divided into four (4) groups of five (5) animals each and treated orally as follows: group 1(normal control) received distilled water (7days), group 2 received 1 g/kg acetaminophen (APAP) (2 days), whereas group 3-4 received APAP (2 days) followed by 500 mg/kg of ALOV and MORN supplements respectively for 5 days. At the end of the experiment, animals from different groups were anaesthesized, the liver and kidney tissues were dissected and blood collected subjected to different biochemical, antioxidants, and histopathological test.
Statistical Analysis: was done using One-Way Anova followed by Tukey’s Post-hoc Test.
Results: APAP caused significant (P<0.05) decrease in creatinine with significant (P<0.01) increase and decrease in liver enzymes and renal catalase levels respectively in relation to normal control. Treatment of rats with the ALOV and MORN supplements attenuated the elevated liver and kidney biochemistry as well as improved histopathological alterations by APAP treatment.
Conclusion: The supplements demonstrated restorative ability. MORN and ALOV supplements extract can be suggested as a convincing remedy against APAP-induced hepato-renal-toxicity.
Systematic Modification of UiO‐66 Metal‐Organic Frameworks for Glucose Conversion into 5‐Hydroxymethyl Furfural in Water
Authors: Oozeerally Ryan , Burnett David L. , Chamberlain Thomas W. , Kashtiban Reza J. , Huband Steven , Walton Richard I. , Degirmenci Volkan 
Published: March 2021

AbstractMetal organic framework UiO‐66 is studied as an adaptable heterogeneous catalyst for glucose conversion. UiO‐66 was modified by; i) partial linker substitution, ii) particle size modulation and iii) linker defects. We studied the effect of crystallinity and functional groups on the glucose conversion and product yields. The main products are: i) fructose from the isomerisation of glucose, ii) mannose from the epimerisation of glucose and iii) 5‐hydroxymethyl furfural from the dehydration of fructose. We found that defective and nano crystalline UiO‐66 catalyst performs best for isomerisation. When 50 % of the linkers of UiO‐66 are replaced by a sulfonate‐containing linker, the catalyst shows higher isomerisation activity than other UiO‐66 catalysts. Naphthalene‐dicarboxylate linkers were introduced to induce hydrophobicity and this catalyst further increased isomerisation activity showing 31 % fructose selectivity. Finally, the promising catalysts were tested in a flow reactor and a bifunctional mixed linker catalyst possessing both hydrophobic and acidic functional groups is shown to be stable in a time‐on‐stream study.
Use of MCM‐41 as an Efficient Adsorbent for Removal of Nonionic Surfactant from Aqueous Solutions
Authors: Akbari Benghar Sedigheh , Zanjanchi Mohammad Ali , Sohrabnezhad Shabnam 
Published: March 2021

AbstractThe as‐synthesized MCM‐41 and its modified forms are used as adsorbents for the removal of nonylphenol ethoxylate (NP‐10) from aqueous solutions. The partial template containing MCM‐41 is prepared by treating the as‐synthesized sample with ethanolic ammonium nitrate solution. Complete removal of the template is performed using the calcination process. The prepared adsorbents are characterized by X‐ray diffraction, Fourier transform infrared spectroscopy, thermogravimetric analysis, transmission electron microscopy, and nitrogen physisorption techniques. The effect of adsorbent weight, pH, contact time, and initial concentration on the adsorption efficiency is studied. The equilibrium adsorption data are well defined, and they are fitted with Langmuir isotherm model. The maximum adsorption capacities (qm) and pseudo‐second‐order rate constants (k2) are calculated. The best adsorbent, in terms of removal efficiency, results to be the thermally treated MCM‐41, characterized by the highest surface area, and thus with the largest porosity. Specifically, the removal efficiency for NP‐10 is around 84% (558 mg g−1) with an initial concentration of 700 mg L−1, which is increased to 91% (455 mg g−1) for a 500 mg L−1 initial concentration. Thermodynamic studies depict that the adsorption of NP‐10 onto MCM‐41 is an endothermic process and the spontaneity is controlled by entropy.
Cell lineage‐ and expression‐based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development
Authors: Takenoshita Manami , Takechi Masaki , Vu Hoang Tri , Furutera Toshiko , Akagawa Chisaki , Namangkalakul Worachat , Aoto Kazushi , Kume Tsutomu , Miyashin Michiyo , Iwamoto Tsutomu , Iseki Sachiko 
Published: March 2021

AbstractBackgroundFoxc2 is a member of the winged helix/forkhead (Fox) box family of transcription factors. Loss of function of Foxc2 causes craniofacial abnormalities such as cleft palate and deformed cranial base, but its role during craniofacial development remains to be elucidated.ResultsThe contributions of Foxc2‐positive and its descendant cells to the craniofacial structure at E18.5 were examined using a tamoxifen‐inducible Cre driver mouse (Foxc2‐CreERT2) crossed with the R26R‐LacZ reporter mouse. Foxc2 expression at E8.5 is restricted to the cranial mesenchyme, contributing to specific components including the cranial base, sensory capsule, tongue, upper incisor, and middle ear. Expression at E10.5 was still positively regulated in most of those regions. In situ hybridization analysis of Foxc2 and its closely related gene, Foxc1, revealed that expression domains of these genes largely overlap in the cephalic mesenchyme. Meanwhile, the tongue expressed Foxc2 but not Foxc1, and its development was affected by the neural crest‐specific deletion of Foxc2 in mice (Wnt1‐Cre; Foxc2fl/fl).ConclusionsFoxc2 is expressed in cranial mesenchyme that contributes to specific craniofacial tissue components from an early stage, and it seems to be involved in their development in cooperation with Foxc1. Foxc2 also has its own role in tongue development.