bluuebunny/crossref_metadata_2025_split huggingface dataset:
Resource-Constrained Scheduling for Multi-Robot Cooperative Three-Dimensional Printing
Authors: Poudel Laxmi , Zhou Wenchao , Sha Zhenghui 
Published: March 2021

Abstract
Cooperative three-dimensional (3D) printing (C3DP)—a representative realization of cooperative manufacturing (CM)—is a novel approach that utilizes multiple mobile 3D printing robots for additive manufacturing (AM). It makes the make-span much shorter compared with traditional 3D printing due to parallel printing. In C3DP, collision-free scheduling is critical to the realization of cooperation and parallel operation among mobile printers. In the extant literature, there is a lack of methods to schedule multi-robot C3DP with limited resources. This study addresses this gap with two methods. The first method, dynamic dependency list algorithm (DDLA), uses a constraint-satisfaction approach to eliminate solutions that could result in collisions between robots and collisions between robots with already-printed materials. The second method, modified genetic algorithm (GA), uses chromosomes to represent chunk assignments and utilizes GA operators, such as the crossover and mutation, to generate diverse print schedules while maintaining the dependencies between chunks. Three case studies, including two large rectangular bars in different scales and a foldable sport utility vehicle (SUV), are used to demonstrate the effectiveness and performance of the two methods. The results show that both methods can effectively generate valid print schedules using a specified number of robots while attempting to minimize the make-span. The results also show that both methods generate a print schedule with equal print time for the first two case studies with homogeneous chunks. In contrast, the modified GA outperforms the DDLA in the third case study, where the chunks are heterogeneous in volume and require different times to print.
James of Viterbo on Seminal Reasons as inchoationes formarum
Authors: Gossiaux Mark 
Published: March 2021

Abstract
This article examines James of Viterbo’s theory of seminal reasons as inchoate forms (inchoationes formarum). James intends this theory to explain how the eduction (eductio) of substantial forms from the potency of matter does not entail that such forms are created ex nihilo. Substantial forms that come to be in generation preexist in matter as forms in potency. The form in potency is an inchoation of, or aptitude or propensity for, the form that comes to be in act. Generation is thus understood by James to be a modal change, for the form in potency and the form in act are one and the same thing (res); they differ only with regard to their mode of being. James’s theory of inchoate forms is a development of Bonaventure’s theory of seminal reasons, but reformulated with the help of Simplicius and Averroes.
Could Cambridge Analytica Have Delivered Donald Trump’s 2016 Presidential Victory? An Anthropologist’s Look at Big Data and Political Campaigning
Authors: Laterza Vito 
Published: March 2021

Abstract
I first provide some context about Cambridge Analytica’s (ca) activities, linking them to ca parent company, scl Group, which specialised in “public relations” campaigns around the world across multiple sectors (from politics to defence and development), with the explicit aim of behavioural change. I then analyse in more detail the claims made by mathematician and machine learning scholar David Sumpter, who dismisses the possibility that ca might have successfully deployed internet psychographics (e.g. online personality profiling) in the winning 2016 Trump presidential campaign in the US. I critique his arguments, pointing at the need to focus on the bigger picture and on the totality of ca methods, rather than analysing psychographics in isolation. This is followed by a section where I use ca whistleblower Christopher Wylie’s 2019 memoir to show the important role that in-depth qualitative research and methods akin ethnographic immersion might have played in building ca big data capabilities. I provide an angle on big data that sees it as complementary, rather than in opposition to, human insight that comes from qualitative immersion in the social realities targeted by ca. The concluding section discusses additional questions that should be explored to gain a deeper understanding of how big data is changing political campaigning, with an emphasis on the important contribution that anthropology can make to these crucial debates.
The effect of socioeconomic status on informal caregiving for parents among adult married females: evidence from China
Authors: Wang Yi , Li Jiajia , Ding Lulu , Feng Yuejing , Tang Xue , Sun Long , Zhou Chengchao 
Published: March 2021

AbstractBackgroundMarried female caregivers face a higher risk of an informal care burden than other caregivers. No study has explored the effect of socioeconomic status (SES) on the intensity of informal care provided by married female caregivers in China. The purpose of this study is to empirically examine how the SES of married female caregivers affects the intensity of the informal care they provide for their parents/parents-in-law in China.MethodsThe data for this study were drawn from 8 waves of the China Health and Nutrition Survey (CHNS). The respondents were married women whose parents/parents-in-law needed care and lived in the same city as them. SES was defined based on four indicators: education, economic status, employment status, andhukou(China’s household registration system). Informal caregivers were divided into three categories: non-caregivers (0 h/week), low-intensity caregivers (less than 10 h/week), and high-intensity caregivers (10 h/week and above). Multinomial logistic regression analysis was used to examine the relation between SES and the likelihood of a low- and high-intensity caregiving among married female caregivers, adjusting for age, family characteristics and survey wave.ResultsOf the 2661 respondents, high-intensity and low-intensity caregivers accounted for 16.35 and 21.27%, respectively. The multinomial logistic regression results showed that the likelihood of being a high-intensity caregiver versus (vs. a non-caregiver) increased as the caregiver’s educational attainment increased (p < 0.05), and that high economic status was related to the likelihood of being a high-intensity caregiver, but this relationship was only significant at the 10% level. Urban females were 1.34 times more likely than their rural counterparts to provide low-intensity care vs. no care (p < 0.05) and were 1.33 times more likely to provide high-intensity care vs. no care (p < 0.05). Employed females were 1.25 times more likely than those unemployed females to provide low-intensity care vs. no care (p < 0.05).ConclusionsDifferences in SES were found between high-intensity caregivers and low-intensity caregivers. Women with high educational attainment and urbanhukouwere more likely to provide high-intensity informal care, and women who were employed and had urbanhukouwere more likely to provide low-intensity care.
APE1 may influence CD4+ naïve T cells on recurrence free survival in early stage NSCLC
Authors: Li Yanping , Zhao Xiaolong , Xiao He , Yang Bo , Liu Jie , Rao Wen , Dai Xiaoyan , Li Mengxia , Dai Nan , Yang Yuxin , Wang Dong 
Published: March 2021

Abstract
Background
It was demonstrated that multifunctional protein APE1 (Apurinic/apyrimidinic endonuclease 1) is closely related to tumor immune microenvironment in a number of investigations, Meanwhile, the abundance of tumor infiltrating lymphocytes (TILs) has been shown as a prognosis indicator in some researches. However, it remains unclear whether APE1 is involved in the process of TILs affecting the prognosis of patients. To this end, we investigated the associations between APE1 and TILs in non-small cell lung cancer (NSCLC) and explored whether APE1 would influence the associations of CD4+ T cells infiltration with the prognosis of patients.

Methods
Genome-wide expression datasets were obtained from the Gene Expression Omnibus (GEO) public database under accession number GSE68465, GSE30219, GSE31210 and GSE50081. MCPcounter and CIBERSORT analysis was conducted to evaluate the abundance of TILs in 1006 NSCLC patients of GEO database. Spearman correlation tests were used to evaluate correlations between abundance of various TILs and APE1 expression. RFS (recurrence free survival) was estimated using the Kaplan–Meier method and the Cox proportional-hazards model. The expression level of APE1 and tumor-infiltrating CD4+ T cells was evaluated by immunohistochemistry (IHC).

Results
The results showed that the abundance of CD4+ naïve T cells was negatively associated with the APE1 expression. CD4+ naïve T cells infiltration was a favorable prognostic factor for RFS, however, there was no effect of CD4+ T cells infiltration on RFS in patients with high APE1 expression. Subsequently, it was further confirmed that CD4+ T cells infiltration was negatively associated with the APE1 expression level in 108 NSCLC tissue samples; high CD4+ T cells infiltration was associated with longer RFS in low APE1 expression group but not in APE1 high expression group.

Conclusion
These results suggested that APE1 may affect the relationship between CD4+ T cells infiltration and prognosis in NSCLC. This study provides new insights into predictors of outcome in patients with NSCLC, and suggests that combining immunotherapy and APE1-targeted therapy may be a promising treatment for NSCLC.
Mindful Melody: feasibility of implementing music listening on an inpatient psychiatric unit and its relation to the use of as needed medications for acute agitation
Authors: Scudamore Trevor , Liem Annette , Wiener Mark , Ekure Nekpen Sharon , Botash Christopher , Empey Derek , Leontieva Luba 
Published: March 2021

Abstract
Background
In this quality improvement project, we set out to study the effectiveness and feasibility of using music as an adjunct or replacement for pharmacologic agitation management on an inpatient psychiatric unit. We hypothesized music intervention would not only assist in de-escalation/calming of agitated patients, but also reduce overall administration of PRN medications on the unit.

Method
The project included 172 volunteer participants over 6 months: Three months without music available and 3 months with a music de-escalation option. During the latter period, patients were given the option of selecting a preferred music genre and provided with wireless headphones for up to 30 min. The number of as needed (PRN) medications administered for agitation and anxiety (including oral, sublingual, and intramuscular routes) was compiled from raw data using pharmacy records. Patients and nurses were provided with self-report surveys regarding the music intervention.

Results
The average weekly PRN medication administrations decreased significantly during the 3 months with music for both haloperidol (8.46 [+/− 1.79, p < 0.05] to 5.00 [+/− 1.44, p < 0.05] administrations/week) and olanzapine (9.69 [+/− 2.32, p < 0.05] to 4.62 [+/− 1.51, p < 0.05] administrations/week), compared to the 3 months prior to music implementation. There was a non-significant increase in administration of lorazepam (3.23 [+/− 1.09, p < 0.05] to 6.38 [+/− 2.46, p < 0.05] average administrations/week). The patient survey responses were 96% positive (non-neutral; either agree or strongly agree with calming effect). Nurses agreed that the project was easy to implement; 56% agreed that music helped to calm patients down. Other exploratory outcomes included observed reductions in average length of hospital stay and number of seclusion events.

Conclusion
Music may play a significant role in reducing the utilization of PRN agitation medications on acute inpatient psychiatric units. More studies are needed to expand on these findings and explore the effect of PRN music on other therapeutic outcomes.

Trial registration
Protocol registration NCT04514432, retrospectively registered on 08/13/2020.
Exploring patterns in psychiatric outpatients’ preferences for involvement in decision-making: a latent class analysis approach
Authors: Mundal Ingunn , Lara-Cabrera Mariela Loreto , Betancort Moisés , De las Cuevas Carlos 
Published: March 2021

Abstract
Background
Shared decision-making (SDM), a collaborative approach that includes and respects patients’ preferences for involvement in decision-making about their treatment, is increasingly advocated. However, in the practice of clinical psychiatry, implementing SDM seems difficult to accomplish. Although the number of studies related to psychiatric patients’ preferences for involvement is increasing, studies have largely focused on understanding patients in public mental healthcare settings. Thus, investigating patient preferences for involvement in both public and private settings is of particular importance in psychiatric research. The objectives of this study were to identify different latent class typologies of patient preferences for involvement in the decision-making process, and to investigate how patient characteristics predict these typologies in mental healthcare settings.

Methods
We conducted latent class analysis (LCA) to identify groups of psychiatric outpatients with similar preferences for involvement in decision-making to estimate the probability that each patient belonged to a certain class based on sociodemographic, clinical and health belief variables.

Results
The LCA included 224 consecutive psychiatric outpatients’ preferences for involvement in treatment decisions in public and private psychiatric settings. The LCA identified three distinct preference typologies, two collaborative and one passive, accounting for 78% of the variance. Class 1 (26%) included collaborative men aged 34–44 years with an average level of education who were treated by public services for a depressive disorder, had high psychological reactance, believed they controlled their disease and had a pharmacophobic attitude. Class 2 (29%) included collaborative women younger than 33 years with an average level of education, who were treated by public services for an anxiety disorder, had low psychological reactance or health control belief and had an unconcerned attitude toward medication. Class 3 (45%) included passive women older than 55 years with lower education levels who had a depressive disorder, had low psychological reactance, attributed the control of their disease to their psychiatrists and had a pharmacophilic attitude.

Conclusions
Our findings highlight how psychiatric patients vary in pattern of preferences for treatment involvement regarding demographic variables and health status, providing insight into understanding the pattern of preferences and comprising a significant advance in mental healthcare research.
The impact of food insecurity on HIV outcomes in Senegal, West Africa: a prospective longitudinal study
Authors: Benzekri Noelle A. , Sambou Jacques F. , Ndong Sanou , Diallo Mouhamadou Baïla , Tamba Ibrahima Tito , Faye Dominique , Sall Ibrahima , Diatta Jean Philippe , Faye Khadim , Cisse Ousseynou , Sall Fatima , Guèye Ndèye Fatou Ngom , Ndour Cheikh T. , Sow Papa Salif , Malomar Jean Jacques , Hawes Stephen E. , Seydi Moussa , Gottlieb Geoffrey S. 
Published: March 2021

Abstract
Background
Understanding the impact of food insecurity on HIV outcomes is critical for the development and implementation of effective, evidence-based interventions to address food insecurity and improve the HIV care cascade. We conducted a prospective, longitudinal study to determine the impact of food insecurity on HIV outcomes in Senegal, West Africa.

Methods
HIV-infected individuals presenting for care and initiation of ART through the Senegalese National AIDS program in Dakar and Ziguinchor were eligible for enrollment. Data were collected using interviews, clinical evaluations, laboratory analyses, and chart review at enrollment, month 6, and month 12. Logistic regression was used to determine the association between food insecurity and HIV outcomes.

Results
Among the 207 participants in this study, 70% were female and the median age was 37 years. The majority (69%) were food insecure at enrollment, 29% were severely food insecure, and 38% were undernourished. Nearly a third (32%) had no formal education, 23% practiced agriculture, and 40% owned livestock. The median daily food expenditure per person was $0.58. The median round trip transportation time to clinic was 90 min (IQR 30–240). The median cost of transportation to clinic was $1.74. At month 12, 69% were food insecure, 23% were severely food insecure, and 14% were undernourished. At month 12, 43% had not disclosed their HIV status; food insecurity was associated with non-disclosure of HIV-status due to fear of stigmatization and feelings of shame. Severe food insecurity was a strong predictor of loss to follow-up (OR 3.13 [1.08–9.06]) and persistent severe food insecurity was associated with virologic failure (OR 5.14 [1.01–26.29]) and poor adherence to ART 8.00 [1.11–57.57]. Poor nutritional status was associated with poor immunologic recovery (OR 4.24 [1.56–11.47]), virologic failure (OR 3.39 [1.13–10.21]), and death (OR 3.35 [1.40–8.03]).

Conclusion
Severity and duration of food insecurity are important factors in understanding the relationship between food insecurity and HIV outcomes. Our findings highlight the importance of nutritional status, socioeconomic opportunity, and self-stigmatization in the complex pathway between food insecurity and HIV outcomes. Interdisciplinary, multisectoral efforts are needed to develop and implement effective interventions to address food insecurity among people living with HIV.
Geographic reach and nutritional quality of foods available from mobile online food delivery service applications: novel opportunities for retail food environment surveillance
Authors: Brar Keshbir , Minaker Leia Michelle 
Published: March 2021

Abstract
Background
Online Food Delivery Services (OFDS) have rapidly expanded in North America, but their implications for geographic access to food and potential dietary outcomes of their use are poorly understood. The purpose of this paper is to examine the extent to which OFDS may geographically expand retail food environments. A secondary objective is to evaluate the healthfulness of foods available on mobile OFDS in a large Canadian city using the Healthy Eating Index-2015 (HEI-2015).

Methods
Retailers’ distance from delivery location was assessed on a large ODFS platform using 24 randomly selected urban postal codes in Ontario, Canada (n = 480 retailers). Distance to the first 10 and the last 10 listed retailers in each postal code was examined in relation to a) city population, b) city population density, and c) whether retailers appeared first or last. Second, to determine the healthfulness of food items available, menus of twelve retailers (n = 759 menu items) from four popular OFDS platforms available in Mississauga, Ontario, were coded using the Food and Nutrient Database for Dietary Studies-2015, and Food Patterns Equivalents Database-2015. Coded items were used to derive HEI-2015 scores.

Results
Delivery distances from the sample of postal codes in Ontario ranged from 0.3 km to 9.4 km (mean 3.7 km), and the total number of retailers available to each postal code ranged from 33 to 472. Substantial, positive correlations existed between total number of retailers available and both city population (r = 0.71), and population density (r = 0.51). HEI-2015 scores for retailers’ full menus were typically low, and ranged from 19.95 to 50.78 out of 100.

Conclusions
OFDS substantially increases geographic access to foods prepared away from home (by up to 9 km and 472 restaurants). Food offerings on OFDS applications do not meet healthy eating recommendations. Given the projected continued rapid expansion of OFDS, particularly in the midst of a global pandemic, surveillance and future research on OFDS and population dietary health is warranted.
Does socio-economic status influence the effect of multimorbidity on the frequent use of ambulatory care services in a universal healthcare system? A population-based cohort study
Authors: MBUYA-BIENGE Cynthia , SIMARD Marc , GAULIN Myles , CANDAS Bernard , SIROIS Caroline 
Published: March 2021

AbstractBackgroundFrequent healthcare users place a significant burden on health systems. Factors such as multimorbidity and low socioeconomic status have been associated with high use of ambulatory care services (emergency rooms, general practitioners and specialist physicians). However, the combined effect of these two factors remains poorly understood. Our goal was to determine whether the risk of being a frequent user of ambulatory care is influenced by an interaction between multimorbidity and socioeconomic status, in an entire population covered by a universal health system.MethodsUsing a linkage of administrative databases, we conducted a population-based cohort study of all adults in Quebec, Canada. Multimorbidity (defined as the number of different diseases) was assessed over a two-year period from April 1st 2012 to March 31st 2014 and socioeconomic status was estimated using a validated material deprivation index. Frequents users for a particular category of ambulatory services had a number of visits among the highest 5% in the total population during the 2014–15 fiscal year. We used ajusted logistic regressions to model the association between frequent use of health services and multimorbidity, depending on socioeconomic status.ResultsFrequent users (5.1% of the population) were responsible for 25.2% of all ambulatory care visits. The lower the socioeconomic status, the higher the burden of chronic diseases, and the more frequent the visits to emergency departments and general practitioners. Socioeconomic status modified the association between multimorbidity and frequent visits to specialist physicians: those with low socioeconomic status visited specialist physicians less often. The difference in adjusted proportions of frequent use between the most deprived and the least deprived individuals varied from 0.1% for those without any chronic disease to 5.1% for those with four or more chronic diseases. No such differences in proportions were observed for frequent visits to an emergency room or frequent visits to a general practitioner.ConclusionEven in a universal healthcare system, the gap between socioeconomic groups widens as a function of multimorbidity with regard to visits to the specialist physicians. Further studies are needed to better understand the differential use of specialized care by the most deprived individuals.