bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamics of a vortex dipole in a holographic superfluid
Authors: Ewerz Carlo , Samberg Andreas , Wittmer Paul 
Published: November 2021

Abstract
We use holography to investigate the dynamics of a vortex-anti-vortex dipole in a strongly coupled superfluid in 2+1 dimensions. The system is evaluated in numerical real-time simulations in order to study the evolution of the vortices as they approach and eventually annihilate each other. A tracking algorithm with sub-plaquette resolution is introduced which permits a high-precision determination of the vortex trajectories. With the increased precision of the trajectories it becomes possible to directly compute the vortex velocities and accelerations. We find that in the holographic superfluid the vortices follow universal trajectories independent of their initial separation, indicating that a vortex-anti-vortex pair is fully characterized by its separation. Subtle non-universal effects in the vortex motion at early times of the evolution can be fully attributed to artifacts due to the numerical initialization of the vortices. We also study the dependence of the dynamics on the temperature of the superfluid.
Quark sivers function at small x: spin-dependent odderon and the sub-eikonal evolution
Authors: Kovchegov Yuri V. , Santiago M. Gabriel 
Published: November 2021

Abstract
We apply the formalism developed earlier [1, 2] for studying transverse momentum dependent parton distribution functions (TMDs) at small Bjorken x to construct the small-x asymptotics of the quark Sivers function. First, we explicitly construct the complete fundamental “polarized Wilson line” operator to sub-sub-eikonal order: this object can be used to study a variety of quark TMDs at small x. We then express the quark Sivers function in terms of dipole scattering amplitudes containing various components of the “polarized Wilson line” and show that the dominant (eikonal) term which contributes to the quark Sivers function at small x is the spin-dependent odderon, confirming the re- cent results of Dong, Zheng and Zhou [3]. Our conclusion is also similar to the case of the gluon Sivers function derived by Boer, Echevarria, Mulders and Zhou [4] (see also [5]). We also analyze the sub-eikonal corrections to the quark Sivers function using the constructed “polarized Wilson line” operator. We derive new small-x evolution equations re-summing double-logarithmic powers of αs ln2(1/x) with αs the strong coupling constant. We solve the corresponding novel evolution equations in the large-Nc limit, obtaining a sub-eikonal correction to the spin-dependent odderon contribution. We conclude that the quark Sivers function at small x receives contributions from two terms and is given by$$ {f}_{1T}^{\perp q}\left(x,{k}_T^2\right)={C}_O\left(x,{k}_T^2\right)\frac{1}{x}+{C}_1\left({k}_T^2\right){\left(\frac{1}{x}\right)}^0+\cdots $$

f

1
T

⊥
q

x

k
T
2

=

C
O

x

k
T
2

1
x

+

C
1

k
T
2

1
x

0

+
⋯
with the function CO(x,$$ {k}_T^2 $$

k
T
2

) varying slowly with x and the ellipsis denoting the subasymptotic and sub-sub-eikonal (order-x) corrections.
Mapping between Witten and lightcone string field theories
Authors: Erler Theodore , Matsunaga Hiroaki 
Published: November 2021

Abstract
We propose a transformation between the off-shell field variables of Witten’s open bosonic string field theory and the traditional lightcone string field theory of Kaku and Kikkawa, based on Mandelstam’s interacting string picture. This is accomplished by deforming the Witten vertex into lightcone cubic and quartic vertices, followed by integrating out the ghost and lightcone oscillator excitations from the string field. Surprisingly, the last step does not alter the cubic and quartic interactions and does not generate effective vertices, and leads precisely to Kaku and Kikkawa’s lightcone string field theory.
THE ASYMPTOTIC SEMIGROUP OF A SUBSEMIGROUP OF A NILPOTENT LIE GROUP
Authors: ABELS HERBERT 
Published: November 2021

AbstractLetSbe a subsemigroup of a simply connected nilpotent Lie groupG. We construct an asymptotic semigroupS0in the associated graded Lie groupG0ofG. We can compute the image ofS0in the abelianization$$ {G}_0^{\mathrm{ab}}={G}^{\mathrm{ab}}. $$G0ab=Gab.This gives useful information aboutS. As an application, we obtain a transparent proof of the following result of E. B. Vinberg and the author: either there is an epimorphismf:G→ ℝ such thatf(s) ≥ 0 for every s inSor the closure$$ \overline{S} $$S¯ofSis a subgroup ofGand$$ G/\overline{S} $$G/S¯is compact.
On the two-dimensional Boussinesq equations with temperature-dependent thermal and viscosity diffusions in general Sobolev spaces
Authors: He Zihui , Liao Xian 
Published: November 2021

AbstractWe study the existence, uniqueness as well as regularity issues for the two-dimensional incompressible Boussinesq equations with temperature-dependent thermal and viscosity diffusion coefficients in general Sobolev spaces. The optimal regularity exponent ranges are considered.
Students’ learning behavior in digital education for radiation oncology
Authors: Vorwerk Hilke , Engenhart-Cabillic Rita 
Published: November 2021

Abstract
Purpose
Digitalization of medical education is an important trend in terms of reforming and modernizing the global education environment. It has been long requested by students and politicians. The goal of this study was to assess the student perception of a newly developed digital educational program in radiation oncology (RO) using an interactive e‑book combined with short learnings clips on a YouTube channel combined with periodic videoconferences and a forum for queries.

Methods
We performed five evaluations during and at the end of two terms with multiple-choice and free-text answers. We evaluated student perception of our new digital learning scenario in three semesters: one pre-clinical and two clinical semesters. In addition, we analyzed all comments from the kMED forum, the YouTube channel, or the e‑mail contacts.
We analyzed the learning behavior of the students based on access to the videos and the number and quality of the reflective questions answered as well as the results of the final examinations.

Results
The students accepted the offer for asynchronous teaching and mainly learned on weekdays (74% of the videos), but also on weekends (23%) and less on public holidays (4%). The answer quality of the reflective questions was good with over 50% correct answers on the first attempt. Learning to be on one’s own authority was very difficult for the students, even in the last clinical semesters of the medical study. Without direct intervention by the teacher, access to the learning material by the students was limited and delayed. Therefore, voluntary interim tests were performed during the first analysis term, which led to an increased number of student accesses to the videos and higher number of answers. Nevertheless, in the first analysis term, the average results in the final exam of the students who did not perform the interim test were below average at 59.1%, and the students who performed the test had better results at 69.5% but this was also not satisfactory. In the second analysis term, we taught with the same digital teaching model but with an additional scheme for learning over the term, 2‑week compulsory intermediate tests, and frequent videoconferences to answer any questions. In this term, we measured a success rate of 93% in the final exam. All annotations were very positive regarding the new educational project. The evaluations showed high acceptance of the new education program. The students stated they would prefer the new education course to be continued in future.

Conclusion
Digital teaching methods make not only the type and quality of teaching transparent, but also the learning behavior of the students. Our analysis has shown that, in addition to the quality of the teaching, the clear structure and specification of the learning content per learning week as well as regular monitoring of what has been learned are of decisive importance for the learning success of the students.
Interpreting global trends in type 2 diabetes complications and mortality
Authors: Ali Mohammed K. , Pearson-Stuttard Jonathan , Selvin Elizabeth , Gregg Edward W. 
Published: November 2021

AbstractInternational trends in traditional diabetes complications (cardiovascular, renal, peripheral vascular, ophthalmic, hepatic or neurological diseases) and mortality rates are poorly characterised. An earlier review of studies published up to 2015 demonstrated that most data come from a dozen high-income countries (HICs) in North America, Europe or the Asia–Pacific region and that, in these countries at least, rates of acute glycaemic fluctuations needing medical attention and amputations, myocardial infarction and mortality were all declining over the period. Here, we provide an updated review of published literature on trends in type 2 diabetes complications and mortality in adults since 2015. We also discuss issues related to data collection, analysis and reporting that have influenced global trends in type 2 diabetes and its complications. We found that most data on trends in type 2 diabetes, its complications and mortality come from a small number of HICs with comprehensive surveillance systems, though at least some low- and middle-income countries (LMICs) from Africa and Latin America are represented in this review. The published data suggest that HICs have experienced declines in cardiovascular complication rates and all-cause mortality in people with diabetes. In parallel, cardiovascular complications and mortality rates in people with diabetes have increased over time in LMICs. However, caution is warranted in interpreting trends from LMICs due to extremely sparse data or data that are not comparable across countries. We noted that approaches to case ascertainment and definitions of complications and mortality (numerators) and type 2 diabetes (the denominator) vary widely and influence the interpretation of international data. We offer four key recommendations to more rigorously document trends in rates of type 2 diabetes complications and mortality, over time and worldwide: (1) increasing investments in data collection systems; (2) standardising case definitions and approaches to ascertainment; (3) strengthening analytical capacity; and (4) developing and implementing structured guidelines for reporting of data.
Graphical abstract
The aspiration test reveals an instability of the posterior horn of the lateral meniscus in almost one-third of ACL-injured patients
Authors: Jacquet Christophe , Mouton Caroline , Magosch Amanda , Komnos George A. , Menetrey Jacques , Ollivier Matthieu , Seil Romain 
Published: November 2021

Abstract
Purpose
Anterior cruciate ligament (ACL) injuries often lead to associated injuries of the posterior horn of the lateral meniscus (PHLM). Arthroscopic, assessment of PHLM instability may be difficult in the absence of a visible meniscus damage. The main objective of this prospective multi-center study was to compare the ability of the probing and aspiration tests to identify PHLM instability in a population of patients undergoing ACL reconstruction (ACLR) and a control group of patients with an intact ACL undergoing knee arthroscopy.

Methods
A prospective case–control analysis was performed in three sports medicine centers. One-hundred and three consecutive patients operated for a primary isolated ACLR without structural lateral meniscus damage other than a root tear were included. They were compared to a control group of 29 consecutive patients who had a knee arthroscopy with an intact ACL and no structural lateral meniscus lesion. The probing and aspiration tests were consecutively executed according to previously published methods.

Results
In the control group, no lateral meniscus lesions were visualized during arthroscopy, and both probing and aspiration tests were negative in all patients. In the group of ACL-injured patients, a Forkel type I–III posterolateral meniscus root tear (PLMRT) was found in 12 patients (12%). In this subgroup, the probing test was positive in 4/12 patients (33%) and the aspiration test in 5 additional patients (75%). In 15 patients (15%), an elongation of the posterior root of the lateral meniscus (defined as type IV PLMRT as an addendum to the Forkel classification) could be observed during arthroscopy. In this subgroup, only 1 patient displayed a PHLM instability with the probing test (7%), whereas the aspiration test was positive in 13/15 patients (87%). In the remaining 76 patients (74%), no structural lesion of the PHLM could be identified. Nevertheless, an instability of the PHLM could be identified in 8 of them (11%) with the probing test, and the aspiration test was positive in 2 additional knees (13%) of this apparently normal subgroup. Altogether, in the entire ACL injury cohort, a positive probing test was observed in 13/103 patients (13%) and a positive aspiration test in 32/103 knees (31%) (p < 0.01).

Conclusion
Careful observation and examination of the PHLM with the aspiration test revealed a substantial amount of previously undiagnosed lateral meniscus instabilities in ACL-injured knees. The prevalence of PHLM instability as evaluated by the aspiration test was high (31%). The aspiration test was superior to the probing test in detecting an instability of the PHLM in a population of ACL-injured patients.

Level of evidence
II.
Automated platform for consistent part realization with regenerative hybrid additive manufacturing workflow
Authors: Avram Oliver , Fellows Chris , Menerini Marco , Valente Anna 
Published: November 2021

AbstractNowadays, the role of hybridization within the wider manufacturing ecosystem gains significant momentum with multiple commercial solutions already available on the market. Despite the very promising benefits of combining and selectively exploiting the advantages of additive and subtractive technologies on the same machine, hybrid additive manufacturing is far from reaching its full potential. One of the central limitations of existing hybrid process chains is the lack of a harmonized, structured and automated workflows to support an adaptive manufacturing strategy. This work is motivated by the need to bridge this gap and to capture the logic behind an adaptive hybrid process chain with the aim to support the achievement of enhanced product quality and improved operational efficiency in hybrid additive manufacturing. The paper discusses the implementation of a hybrid CAx platform and the underlying methodology aiming at the dynamic reduction of variabilities associated with the laser metal deposition process. The hybrid workflow identifies the most adapted sequence and planning of additive and subtractive operations while considering part inspection as an in-envelope functionality to quantify the geometrical and dimensional part deviations and to trigger the regenerative mechanism. The methodology is demonstrated on a hybrid machine by deploying laser ablation for the in situ removal of build deviations and an adapted deposition operation as part of a regenerative strategy leading to higher part confidence.
Re﻿placing dietary animal-source proteins with plant-source proteins changes dietary intake and status of vitamins and minerals in healthy adults: a 12-week randomized controlled trial
Authors: Pellinen Tiina , Päivärinta Essi , Isotalo Jarkko , Lehtovirta Mikko , Itkonen Suvi T. , Korkalo Liisa , Erkkola Maijaliisa , Pajari Anne-Maria 
Published: November 2021

Abstract
Purpose
A shift towards more plant-based diets promotes both health and sustainability. However, controlled trials addressing the nutritional effects of replacing animal proteins with plant proteins are lacking. We examined the effects of partly replacing animal proteins with plant proteins on critical vitamin and mineral intake and statuses in healthy adults using a whole-diet approach.

Methods
Volunteers aged 20–69 years (107 female, 29 male) were randomly allocated into one of three 12-week intervention groups with different dietary protein compositions: ANIMAL: 70% animal-source protein/30% plant-source protein; 50/50: 50% animal/50% plant; PLANT: 30% animal/70% plant; all with designed protein intake of 17 E%. We analysed vitamin B-12, iodine, iron, folate, and zinc intakes from 4-day food records, haemoglobin, ferritin, transferrin receptor, folate, and holotranscobalamin II from fasting blood samples, and iodine from 24-h urine.

Results
At the end point, vitamin B-12 intake and status were lower in PLANT than in 50/50 or ANIMAL groups (P ≤ 0.007 for all). Vitamin B-12 intake was also lower in 50/50 than in ANIMAL (P < 0.001). Iodine intake and status were lower in both 50/50 and PLANT than in ANIMAL (P ≤ 0.002 for all). Iron and folate intakes were higher in PLANT than in ANIMAL (P < 0.001, P = 0.047), but no significant differences emerged in the respective biomarkers.

Conclusions
Partial replacement of animal protein foods with plant protein foods led to marked decreases in the intake and status of vitamin B-12 and iodine. No changes in iron status were seen. More attention needs to be paid to adequate micronutrient intakes when following flexitarian diets.

Clinical trial registry
NCT03206827; registration date: 2017–06-30.
Tacks vs. sutures: a biomechanical analysis of sacral bony fixation methods for laparoscopic apical fixations in the porcine model
Authors: Jansen Alina Katharina , Ludwig Sebastian , Malter Wolfram , Sauerwald Axel , Hachenberg Jens , Pahmeyer Caroline , Wegmann Kilian , Rudroff Claudia , Karapanos Leonidas , Radosa Julia , Trageser Nadja , Eichler Christian 
Published: November 2021

Abstract
Purpose
There is a novel surgical procedure, called cervicosacropexy (CESA) and vaginosacropexy (VASA) to treat pelvic organ prolapse and a concomitant urgency and mixed urinary incontinence. As there is little experience with the tapes so far and literature is scanty, the aim of this study was to investigate biomechanical properties for the fixation of the PVDF-tapes with three different fixation methods in context of apical fixations.

Methods
Evaluation was performed on porcine, fresh cadaver sacral spines. A total of 40 trials, divided into 4 subgroups, was performed on the anterior longitudinal ligament. Recorded biomechanical properties were displacement at failure, maximum load and stiffness in terms of the primary endpoints. The failure mode was a secondary endpoint. Group 4 was a reference group to compare single sutures on porcine tissue with those on human tissue. Biomechanical parameters for single sutures on the human anterior longitudinal ligament were evaluated in a previous work by Hachenberg et al.

Results
The maximum load for group 1 (two single sutures) was 65 ± 12 N, for group 2 (three titanium tacks arranged in a row) it was 25 ± 10 N and for group 3 (three titanium tacks arranged in a triangle) it was 38 ± 12 N. There was a significant difference between all three groups. The most common failure mode was a “mesh failure” in 9/10 trials for groups 1–3.

Conclusion
The PVDF-tape fixation with two single sutures endures 2.6 times more load than titanium tacks arranged in a row and 1.7 times more load than titanium tacks arranged in a triangle. The presacral fixation with titanium tacks reduced surgical time compared to the fixation with sutures, nevertheless sutures represent the significantly stronger and cheaper fixation method.
Characterizing the sensorimotor domain in schizophrenia spectrum disorders
Authors: Fritze Stefan , Sambataro Fabio , Kubera Katharina M. , Brandt Geva A. , Meyer-Lindenberg Andreas , Wolf Robert C. , Hirjak Dusan 
Published: November 2021

AbstractThe rapidly evolving field of sensorimotor neuroscience reflects the scientific and clinical relevance of sensorimotor abnormalities as an intrinsic component of the disease process, e.g., in patients with schizophrenia spectrum disorders (SSD). Despite previous efforts, however, prevalence rates and relationships between different categories of sensorimotor abnormalities in SSD patients are still subject of ongoing debate. In this study, we examined five different categories of the sensorimotor domain (Neurological soft signs (NSS), parkinsonism, catatonia, akathisia, and tardive dyskinesia) according to well-established clinical ratings scales and the respective cut-off criteria in a sample of 131 SSD patients. We used a collection of statistical methods to better understand prevalence, overlap and heterogeneity, as well as psychopathological and cognitive correlates of sensorimotor abnormalities. 97.7% of the SSD patients considered by this study exhibited at least one categorically defined sensorimotor abnormality that tended to co-vary within three different sensorimotor subgroups (moderate, hyperkinetic and hypokinetic). Finally, hyperkinetic and hypokinetic groups differed significantly in their neurocognitive performance compared with the moderate group. The results suggest different patterns of clinical overlap, highlight the relationship between sensorimotor and cognitive domain and provide clues for further neurobiological studies.
A population-based follow-up study shows high psychosis risk in women with PCOS
Authors: Karjula Salla , Arffman Riikka K. , Morin-Papunen Laure , Franks Stephen , Järvelin Marjo-Riitta , Tapanainen Juha S. , Miettunen Jouko , Piltonen Terhi T. 
Published: November 2021

AbstractPolycystic ovary syndrome (PCOS) is a common endocrine disorder affecting up to 18% of women. Besides metabolic and fertility aspects, attention has lately been directed towards the detrimental effect of PCOS on psychological health. The objective of the study was to investigate whether women with PCOS are at higher risk for psychotic disorders. The study population derives from the Northern Finland Birth Cohort 1966 (N = 5889 women). The women with PCOS were identified by two simple questions on oligo-amenorrhea and hirsutism at age 31. Women reporting both symptoms were considered PCOS (N = 124) and asymptomatic women as controls (N = 2145). The diagnosis of psychosis was traced using multiple national registers up to the year 2016. Symptoms of psychopathology were identified using validated questionnaires at age 31. Women with PCOS showed an increased risk for any psychosis by age 50 (HR [95% CI] 2.99, [1.52–5.82]). Also, the risk for psychosis after age 31 was increased (HR 2.68 [1.21–5.92]). The results did not change after adjusting for parental history of psychosis, nor were they explained by body mass index or hyperandrogenism at adulthood. The scales of psychopathology differed between women with PCOS and non-PCOS controls showing more psychopathologies among the affected women. PCOS cases were found to be at a three-fold risk for psychosis, and they had increased psychopathological symptoms. PCOS should be taken into consideration when treating women in psychiatric care. More studies are required to further assess the relationship between PCOS and psychotic diseases.