bluuebunny/crossref_metadata_2025_split huggingface dataset:
The COVID-19 Inflation Weighting in Israel
Authors: Benchimol Jonathan , Caspi Itamar , Levin Yuval 
Published: December 2021

Abstract
Significant shifts in the composition of consumer spending as a result of the COVID-19 crisis can complicate the interpretation of official inflation data, which are calculated by the Central Bureau of Statistics (CBS) based on a fixed basket of goods. We focus on Israel as a country that experienced three lockdowns, additional restrictions that significantly changed consumer behavior, and a successful vaccination campaign that has led to the lifting of most of these restrictions. We use credit card spending data to construct a consumption basket of goods representing the composition of household consumption during the COVID-19 period. We use this synthetic COVID-19 basket to calculate the adjusted inflation rate that should prevail during the pandemic period. We find that the differences between COVID-19-adjusted and CBS (unadjusted) inflation measures are transitory. Only the contribution of certain goods and services, particularly housing and transportation, to inflation changed significantly, especially during the first and second lockdowns. Although lockdowns and restrictions in developed countries created a significant bias in inflation weighting, the inflation bias remained unexpectedly small and transitory during the COVID-19 period in Israel.
Phonaesthemic alternations in Flemish dialects: a matter of language contact in the emergence of phonaesthesia?
Authors: Robbe Joost , Willemsen Jeroen 
Published: December 2021

AbstractIn this article, we present and analyse phonaesthemic alternations as they appear in Flemish dialects of Dutch, that is when a root-initial consonant or consonant cluster is replaced by a post-alveolar affricate /ʧ/ or /ʤ/ in order to create a phonaesthemically marked variant of a neutral base word. Although no longer productive in Flemish dialects, we show that such phonaesthemic alternations exhibit strong functional similarities to those found in other languages, in particular the evaluative notions of diminutivity and augmentativity. We also show that, formally speaking, Flemish phonaesthemic alternations differ from those attested in other languages in only targeting a single consonant or consonant cluster. We then put forward the hypothesis that Flemish speakers may have copied this mechanism to produce phonaesthemic alternations from Picard speakers, corroborating the notion that phonaesthemic alternations may emerge from language contact.
Ground motion of the Ms7.0 Jiuzhaigou earthquake
Authors: Wang Wencai , Chen Jifeng , Su Xiaoyun , Wu Lina , Chen Lijun , Jiang Zhijie , Shi Wenbing , Wang Yan , Liu Hongmei 
Published: December 2021

Abstract
Eighty-eight free-field strong ground motion observation datasets obtained by the National Strong Motion Observation Network System of China for the Jiuzhaigou Ms7.0 earthquake were used to study the characteristics of the strong ground motion and the site response. In this study, we calculated the VS30 of the near field station and compared the observed values of the horizontal peak acceleration and peak velocity with the CB2014 ground motion prediction models developed by Campbell et al. (2014). The results indicate that the observed values of the horizontal peak acceleration and peak velocity of the Jiuzhaigou earthquake are both smaller than the predicted values obtained from the ground motion prediction equations. By regressing the spatial variation curves of the D
SR (5–95%) and D
SR (5–75%) ground motion durations, and comparing them with Bommer’s (2009) ground motion duration prediction curve, it was found that the duration of the Jiuzhaigou earthquake was greater than that obtained from the global empirical prediction equation. The scope of the source duration corresponding to the D
SR (5–75%) duration is 2.76–4.28 s, and the scope of the source duration corresponding to the D
SR (5–95%) duration is 8.88–10.36 s, which are close to the peak time and completion time of the seismic moment release during the source rupture process. The linear elastic acceleration response spectra of 11 stations within 100 km of the fault were calculated for comparison with the design spectrum. It was concluded that the range of the predominant period of the response spectrum was 0.05–0.26 s, which is less than the natural vibration period of the local multistory building. However, the response spectrum value recorded by station 51JZZ is greater than the design spectrum of the 8° rare earthquake and the observation values of the nearby strong ground motion stations. Through analysis of the H/V spectrum ratio and the case of station 51JZZ, which is closest to the epicenter, this phenomenon was concluded to be related to the magnification effect of the near-surface soil layer and the nonlinear response of the site under the action of strong earthquakes.
Water quality assessment and spatial–temporal variation analysis in Erhai lake, southwest China
Authors: Chen Xuekai , Liu Xiaobo , Li Bogen , Peng Wenqi , Dong Fei , Huang Aiping , Wang Weijie , Cao Feng 
Published: December 2021

Abstract
For the implementation of lake ecological protection, understanding the water pollution status and spatio–temporal variation of water quality has become the most important thing for water safety in the basin. To analyze the water quality in recent years, water quality data in Erhai lake from 2013 to 2017 were first collected from typical nine monitoring stations. Based on the comprehensive water quality index (WQI) method, the temporal and spatial variation characteristics of water quality in Erhai lake were analyzed, and the main factors affecting water quality in Erhai lake were explored. The results indicated that the water quality of Erhai lake was worse than its target water quality, and total nitrogen (TN) and total phosphorus (TP) exceeded the Class Ⅱ standards (TN: 0.5 mg L−1, TP: 0.025 mg L−1) of China’s Environmental Quality Standard for Surface Water (GB3838-2002). In terms of changes across seasons, the overall lake water quality in the dry season was better than that in the wet season, and TN and TP reached the peak value in September. In terms of spatial distribution, water quality of the northern area was better than that of the southern area in the dry season, whereas water quality of the southern area was better than that of the northern area in the wet season. At present, Erhai lake is at a critical turning point of water eutrophication, and its nutrition status is mainly affected by both nitrogen and phosphorus. The pollution load from the land area is the main factor affecting the deterioration of Erhai lake. Our results can provide a scientific basis for the treatment of the water environment of Erhai lake.
Digital Resources Integration and Performance Evaluation Under the Knowledge Management Model in Academic Libraries
Authors: Rafi Muhammad , Islam A.Y.M. Atiquil , Ahmad Khurshid , Zheng Jian Ming 
Published: December 2021

Abstract
Leveraging a knowledge management model (KMM), organizing digital resources, and measuring performance beyond digital libraries continue to be hot topics for many organizations. Given its growing importance, the aim of this study was to design a robust integrated research model based on social cognitive theory and KMM to organize resources and improve the productivity of academic librarians to make services effective. Using a quantitative method based on key data collected by librarians at Pakistani universities, the researchers reviewed previously published literature and sought expert opinions to develop a research tool. The authors distributed 350 printed questionnaires to professionals from 190 universities, of which 339 were returned. These were analyzed to test the hypotheses and assess the accuracy of the measurement and structural models. After undergoing rigorous statistical analysis, the seven constructs using Social Cognitive Theory and the Knowledge Management Model have proven to be suitable for digital asset integration, employee productivity measurement, and high-quality academic services. In addition, the model based on social cognitive theory supports the application of KMM to promote knowledge culture, resource organization, and successful integration and innovation of academic services by enhancing the technical and professional skills of staff in academic institutions.
Contemporary nano-architectured drugs and leads for ανβ3 integrin-based chemotherapy: Rationale and retrospect
Authors: Abbas Nahid , Yusuf Mohammad , Akhtar Naseem , Khan Riaz A. 
Published: December 2021

Abstract
The integrins belong to the cell-surface polypeptide family and are the mediating partners among the cells, and extracellular matrix (ECM). They are also involved in the biological processes of cell migration, wound healing, blood clotting, immunological response generation, tissue morphogenesis, leucocyte reticulations, and angiogenesis and are therefore very relevant in stem cell technology and are useful as biomarkers, diagnostic probes, and drug-target ligands. The ανβ3 (alpha-nu-beta3) integrin antagonists are an excellent target example for designing and developing newer drug candidates, drug leads and templates for various diseases, and physiological malfunctioning, including cancers. The current review examines the ανβ3 integrin structural features involved in the drug design and its antagonistic ligands and highlights the development of anti-ανβ3 integrin-antagonists as nano-architectural design-based nanomedicine, especially for cancer chemotherapy. The perspectival review discusses the ανβ3 integrin structure, mode of action, involved pathways, and the concepts utilized in nanomedicine design, and ligands related to integrins. It also covers the latest thyrointegrin approaches toward the development of anti-angiogenesis agents and entails the anti-angiogenesis approach to cancer growth inhibition through targeting by the anti-integrin ligands and related chemical entities. The current perspective on the nano-architectural design approach for the known anti-integrin compounds is also outlined.
Miniaturized peptidomimetics and nano-vesiculation in endothelin types through probable nano-disk formation and structure property relationships of endothelins’ fragments
Authors: Khan Riaz A. , Khan Azra J. 
Published: December 2021

Abstract
Endothelins (ETs), which are multi-functional-peptides with potential for antagonist-based-therapy in various physiological-malfunctionings, including cardiovascular, nephrological, oncologic, and diabetic conditions, may produce newer chemical entities and drug leads. The present study deals with molecular-modeling of the ETs’ sub-types, ET-I, II, and III to find the structure property-relationship (SPR) of the ETs, and individual fragments derived from the ET sub-type ET-I. The ETs peptidic tails’ amino acid (AA) sequence’s structural differences and similarities, various dissected fragments of the ET-I, and SPR comparison with the sarafotoxin-6b (SRT-6b), a structurally-related snake-venom, showed points of dissimilarities for their structural specifications, geometric disposition, and physico-chemical properties. The generation of miniaturized (shortened sequence) peptides towards offering peptidomimetic compounds of near- and far-values compared SPR with estimations for log P, hydration energy, and other molecular and quantitative structure activity relationship (QSAR) were based on random and ordered-fragments derived from the original ET-I AA’s sequence, and sequential distance changes in the original ET-I sequence’s chain of 1–21 AA. The feasibility of alternate and bond length parameters-based possible cysteine–cysteine cyclizations, sequence homology, AA’s positional demarcation, and presence/absence of cysteines, homology-based basic non-cysteine and cysteines-AA based cyclization, total structure and fragments end-to-end cyclizations, and geometrical analogy-based miniaturized sequence of the shorter AAs from the original ET-I sequence, together with mutated replacements with naturally constituent AAs of the ETs, and SRT-6 sequences were utilized. The major findings of the fragmented sequences, and sequences at par with the original ETs to provide structures similar to the size, volume and with molecular and electronic properties of electrostatic potential and total charge density distribution, crucial factors in receptor bindings were investigated. The SPRs, molecular properties, and QSAR values were estimated to compare and validate the findings with the known homologous compounds, ET-I, and its known and potent antagonists. The study resulted in leads of smaller and larger sizes of peptide-based compounds which may have prospects as potent antagonist and in future needs their bioactivity evaluations after the synthesis. Moreover, approach to plausible vesiculation of the ETs, and the involved processes and structural requirements, together with the molecular interactions in settling a nano-vesicle of the peptidic structure with a possible mechanism is also suggested.
Effect of ultrasonic field on the microstructure and mechanical properties of sand-casting AlSi7Mg0.3 alloy
Authors: Yin Peng , Xu Chunguang , Pan Qinxue , Guo Canzhi , Jiang Xiaowei 
Published: December 2021

Abstract
The injection of ultrasonic wave into a melt during casting can refine grain size, improve grain distribution, and thereby enhance casting performance. The available studies on ultrasonic-assisted casting are mostly about inserting a transducer directly into the melt. Such a method is not suitable for sand casting. Therefore, the study of ultrasonic sand casting by indirectly injecting ultrasonic waves into an aluminum alloy melt through a sand mold was proposed and carried out in this study. The effects of ultrasonic waves of different powers at different solidification stages on the microstructure and mechanical properties of the melt were studied. Compared to conventional sand casting, the samples prepared by ultrasonic sand casting have finer grains and better grain distribution, as well as higher mechanical properties. Moreover, the sample’s performance improves to different levels when the same ultrasonic wave is injected at different periods, when compared to the injection of ultrasonic waves with different powers in the same period.
Big data analytics opportunities for applications in process engineering
Authors: Sadat Lavasani Mitra , Raeisi Ardali Nahid , Sotudeh-Gharebagh Rahmat , Zarghami Reza , Abonyi János , Mostoufi Navid 
Published: December 2021

Abstract
Big data is an expression for massive data sets consisting of both structured and unstructured data that are particularly difficult to store, analyze and visualize. Big data analytics has the potential to help companies or organizations improve operations as well as disclose hidden patterns and secret correlations to make faster and intelligent decisions. This article provides useful information on this emerging and promising field for companies, industries, and researchers to gain a richer and deeper insight into advancements. Initially, an overview of big data content, key characteristics, and related topics are presented. The paper also highlights a systematic review of available big data techniques and analytics. The available big data analytics tools and platforms are categorized. Besides, this article discusses recent applications of big data in chemical industries to increase understanding and encourage its implementation in their engineering processes as much as possible. Finally, by emphasizing the adoption of big data analytics in various areas of process engineering, the aim is to provide a practical vision of big data.
Hypoalgesia after exercises with painful vs. non-painful muscles in healthy subjects – a randomized cross-over study
Authors: Hansen Simon , Petersen Kristian Kjær , Sloth Emilie , Manum Line Appelon , McDonald Anita Kjær , Andersen Per Grünwald , Vaegter Henrik Bjarke 
Published: December 2021

Abstract

Objectives
Exercise-induced hypoalgesia (EIH) is a decrease in the pain sensitivity after exercise. Individuals with chronic pain show less EIH after one exercise session compared with pain-free individuals possibly due to pain in exercising muscles. The primary aim of this randomized controlled cross-over study was to compare the EIH response at the exercising thigh muscle following exercises performed with painful vs. non-painful muscles. Secondary aims were to explore if a reduced EIH response was confined to the painful muscle, and whether the muscle pain intensity and the EIH responses were negatively associated.

Methods
In two sessions, 34 pain-free participants received a painful (hypertonic saline, 5.8%) injection and a control (isotonic saline, 0.9%) injection in the right thigh muscle before performing a 3 min isometric wall squat exercise. Pressure pain thresholds (PPTs) were assessed at both thighs and the left neck/shoulder at baseline, after injections and after exercise. Pain intensities in the thighs were rated on numerical rating scales (NRS: 0–10).

Results
Hypertonic saline induced moderate thigh pain at rest (NRS: 4.6 ± 2.1) compared to the control injection (NRS: 0.3 ± 0.4; p<0.001). EIH at the thighs and neck/shoulder were not different between sessions (Injected thigh: 0 kPa; 95% CI: −51 to 52; Contralateral thigh: −6 kPa; 95% CI: −42 to 30; neck/shoulder: 19 kPa; 95% CI: −6 to 44). No significant associations between pain intensity ratings immediately after the Painful injection and EIH responses at any assessment sites were found (right thigh: β=0.08, 95% CI: −12.95 to 20.64, p=0.64, left thigh: β=−0.33, 95% CI: −27.86 to 0.44, p=0.06; neck/shoulder: β=−0.18, 95% CI: −15.11 to 4.96, p=0.31).

Conclusions
Pain in the area of an exercising muscle did not reduce local or systemic EIH responses.

Trial registration number
NCT04354948.
MAP3K1 SNP rs889312 potential risk and MAP3K9 SNP rs11628333 menopause dependent association for breast cancer
Authors: Abbasi Samina Asghar , Baig Ruqia Mehmood , Ahmed Mehvish Naseer , Ismail Muhammad , Khan Rashida , Mehmood Humera , Mansoor Qaisar 
Published: December 2021

Abstract

Objectives
Breast cancer is the leading cause of mortality in today’s world. An alarming rise in cancer incidence has been observed in the South Asian region. The aberrant molecular mechanisms regulating cell proliferation and development contribute to cancer development. A better understanding of the detailed molecular mechanisms at genetic and epigenetic levels can help to treat breast cancer more efficiently. The present study is aimed to identify the possible association of MAP3K1 SNP rs889312 and MAP3K9 rs11628333 in breast cancer in the South Asian region.

Methods
Female breast cancer patients were recruited in the study. DNA was isolated from the blood samples collected from the patients. PCR-RFLP was used for genotyping, and data analysis was done by SPSS software.

Results
Genotyping data for MAP3K1 SNPrs889312 showed statistically significant association with breast cancer, while MAP3K9 SNPrs11628333 showed characteristic association of rare allele heterozygote’s and homozygotes in pre and post-menopausal patients, respectively.

Conclusions
The study concludes a strong association of the rs889312 with breast cancer in the Pakistani population and a characteristic association of unique genotypes TC and CC in pre- and post-menopausal breast cancer patients. These findings can provide a ready tool as a breast cancer marker in south Asian populations.
Intrasession and Intersession Reliability of Isometric Squat, Midthigh Pull, and Squat Jump in Resistance-Trained Individuals
Authors: Ishida Ai , Suarez Dylan G. , Travis S. Kyle , Slaton Jake A. , White Jason B. , Bazyler Caleb D. , Stone Michael H. 
Published: December 2021

Abstract
Ishida, A, Suarez, DG, Travis, SK, Slaton, JA, White, JB, Bazyler, CD, and Stone, MH. Intrasession and intersession reliability of isometric squat, midthigh pull, and squat jump in resistance-trained individuals. J Strength Cond Res 37(1): 18–26, 2023—The purposes of this study were to investigate intrasession and intersession reliability of variables obtained from squat jump (SJ), shortened isometric midthigh pull (IMTP), and isometric squat (ISQ) protocols and to evaluate relationships between isometric and dynamic performance and 1 repetition maximum (1RM) back squat (BSQ). Eleven moderately resistance-trained men participated (27.8 ± 3.9 years; 175.0 ± 7.2 cm; 87.2 ± 11.4 kg). Subjects completed familiarization in the IMTP and ISQ, followed by 1RM BSQ at least 48 hours before the first performance test. Two performance tests occurred at 7-day intervals including SJ, IMTP, and ISQ. SJ variables included jump height (SJH), body mass (BM), peak force (PF), and peak power (PP). Isometric midthigh pull and ISQ variables included isometric peak force (IPF); relative IPF; rate of force development at 90, 200, and 250 milliseconds; and impulse at 90, 200, and 250 milliseconds. SJ, IMTP, and ISQ kinetic variables were considered reliable if intraclass correlations (ICCs) and coefficients of variations (CVs) were >0.80 and <10%. Intrasession and intersession reliability criteria were met for SJH, BM, PF, and PP (ICC = 0.91–1.00, CV = 0.5–9.1%). Isometric peak force and impulse at 200 and 250 milliseconds met intrasession and intersession reliability criteria for IMTP and ISQ (ICC = 0.90–0.99, CV = 2.1–8.1%). Significant large correlation was observed between 1RM BSQ and ISQ peak force (p = 0.038, r = 0.63), but not between 1RM BSQ and shortened IMTP peak force (p = 0.11, r = 0.50). Shortened IMTP and ISQ peak force and impulse are reliable kinetic variables, and ISQ peak force is indicative of 1RM BSQ in moderately resistance-trained men.
Effects of Maturation on Lower-Body Neuromuscular Performance in Youth Tennis Players
Authors: Fernandez-Fernandez Jaime , Canós-Portalés Jose , Martinez-Gallego Rafael , Corbi Francisco , Baiget Ernest 
Published: December 2021

Abstract
Fernandez-Fernandez, J, Canós-Portalés, J, Martinez-Gallego, R, Corbi, F, and Baiget, E. Effects of maturation on lower body neuromuscular performance in youth tennis players. J Strength Cond Res 37(1): 167–173, 2023—The aim of this study was to examine the maturational status differences in neuromuscular performance of young tennis players. One hundred fifty-five junior tennis players (91 boys and 64 girls; age 13.1 ± 2.2 years, body mass 50.0 ± 12.2 kg, height 159.7 ± 12.4 cm, and estimated age at peak height velocity [PHV] 12.7 ± 1.6 years) participated in the study and were divided into pre-PHV (n = 57), circa-PHV (n = 50), and post-PHV (n = 48) groups. Physical tests included speed (5, 10, and 20 m), modified 5-0-5 change of direction (COD) test, hexagon test, and bilateral or unilateral countermovement jump (CMJ). The main results showed that compared with the post-PHV, pre-PHV players presented lower levels of performance in CMJs (p < 0.001; effect size [ES]: 0.76–0.88), linear sprints, and COD ability tests (p < 0.001; ES: 1.4–1.5). In addition, compared with circa-PHV, pre-PHV players also demonstrated lower performance levels in both linear sprints (p < 0.001; ES: 0.93–1.12) and COD abilities (p < 0.01; ES: 0.58–0.94). On the contrary, COD deficit (CODDEF) was significantly lower in the pre-PHV group than the circa-PHV (p < 0.001; ES: 0.76–0.79) and post-PHV (p < 0.001; ES: 1.04–1.05) groups. These results highlight the need to use the maturity stage (i.e., PHV) instead of chronological age as a more appropriate parameter when designing training programs. Furthermore, based on the differences found between groups, specific training strategies, such as neuromuscular training and COD workouts, related to the different maturation stages should be recommended.