bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of tuberculosis infection among children and adolescents with positive results of a skin test with recombinant TB allergen
Authors: Baronova O. D. , Aksenova V. A. , Baryshnikova L. A. , Kudlay D. A. , Nakonechnaya S. L. 
Published: November 2021

Introduction. In the context of a decrease in the tension of the epidemic situation on tuberculosis in Russia, it remains relevant to search for new ways to increase the effectiveness of preventive anti-tuberculosis measures among children and teenagers, taking into account an integrated approach to assessing all risk factors for tuberculosis in various age groups of the child population.Objective. Tо study the complex characteristics of groups at increased risk of tuberculosis among children of different ages who have positive results of a skin test with a recombinant tuberculous allergen (АТR).Materials and methods. The study retrospectively included 392 patients aged 2–17 years with a positive ATR test result. The рatients were randomized by age into 3 groups: in the 1st group there were 87 children 2–7 years old, in the 2nd group 182 children aged 8–14 years were included, in the 3rd group included 121 patients 15–17 years. The children did not have clinical and radiological signs of active tuberculosis and were HIV-negativ.Result. Among children and adolescents with a positive result of the test with ATR, social risk factors for developing tuberculosis (unfavorable living conditions, lack of permanent employment in 86.3% of parents) were determined. It was found that children living in families with low social status were dominated by contact with patients with multidrug resistance of the pathogen (MDR-TB), more than half of children (53.1%) had comorbidities. In 13.3% of children, small calcifications were detected in the lungs, in the intrathoracic lymph nodes.Conclusion. Among children 2–7 years old with positive results of the test with ATR, a complex of risk factors for the development of tuberculosis prevails: low material security in every second family, alcohol and drug dependence of parents in every third family, contact with MDR-TB patients in 56.5% of children, high incidence of concomitant pathology (in 67.4% of children).
Assessment of life quality indicators and the role of commitment in achieving control in severe bronchial asthma
Authors: Sobko E. A. , Demko I. V. , Kraposhina A. Yu. , Gordeeva N. V. , Ischenko O. P. , Egorov S. A. , Okulova D. N. , Smolnikov N. S. , Avdeeva A. I. 
Published: November 2021

Introduction. One of their main aspects in the treatment of patients with bronchial asthma is maintaining adequate control over the course of the disease.The aim: to assess the level of control, the causes of the uncontrolled course of the disease and the quality of life in patients with severe bronchial asthma.Materials and methods. The study involved 160 patients with severe bronchial asthma taking basic anti-inflammatory therapy. The assessment of adherence to baseline therapy was assessed by questionnaires of patients with a modified Morisky-Green questionnaire and a test to assess adherence to inhalers (TAI). A quality of life questionnaire for patients with bronchial asthma (AQLQ) was used to assess quality of life.Results. It was revealed that all patients had reported daily symptoms and a daily need for short acting beta-agonists; 96.6% of the patients enrolled in the study had night awakenings and physical activity restriction. The survey of patients with the help of the Morisky-Green questionnaire showed that deliberate low adherence to therapy was noted in 45.6% of cases, which was formed due to inattention to the hours of medication – 67.1% and missing the drug in good health in 47.9% of patients. Low motivation and low awareness of their disease is recorded in 24.4% of patients.Conclusions. All patients did not achieve control of the disease. In half of patients with severe asthma, there is low deliberate adherence to basic anti-inflammatory therapy, which is formed mainly by missing the drug in good health and inattention to the hours of medication. Asthma symptoms have the greatest impact on the patient’s emotional state, physical activity, and overall quality of life.
Antidiabetic Properties of Dietary Chrysin: A Cellular Mechanism Review
Authors: Dewi Rita Marleta , Megawati Megawati , Antika Lucia Dwi 
Published: November 2021

Abstract:
Diabetes mellitus is the most common chronic metabolic disorder and is considered one
of the leading causes of morbidity and mortality. The improperly-treated chronic hyperglycemia of
diabetes has been related to several long-term complications and multiple organ failures, including
nephropathy, which can lead to kidney failure, retinopathy with the potential loss of vision, and cardiovascular
symptoms. Current commercially available synthetic glucose-lowering agents have been
reported to have several adverse effects. Therefore, the search for alternative remedies such as medicinal
plants and their active compounds have attracted attention. Chrysin is an active flavonoid
that exists widely in various plants and diets and has been reported to possess pharmacological
properties, including antidiabetic activity. Many studies have been conducted to characterize the
antidiabetic of chrysin, as well as its potential pathways, in in vitro and in vivo experiments. Chrysin
has shown promise as an antidiabetic agent in animal studies, thus, demonstrating its potential to be
developed as an antidiabetic drug. This review discussed the antidiabetic action of chrysin and its
mechanisms, including targeting different mechanisms such as stimulation of insulin signaling,
blockage of endoplasmic reticulum stress and oxidative damage, promotion of skeletal glucose uptake,
as well as modulation of apoptosis and autophagy signaling. Additionally, this review would
be useful for further studies regarding the mechanism of work of plant derived-compound as a potential
antidiabetic agent.
Molecular Study of Immune Evasion Cluster Genes in Clinical Isolates of Staphylococcus aureus
Authors: Zaki Maysaa El Sayed , El-Kazzaz Samah Sabry 
Published: November 2021

Aims:
The aim of the present research was to highlight the prevalence of immune evasion
cluster genes (IEC) sak, chp, scn, sea, sep among Staphylococcus aureus (S. aureus) clinical
isolates.

Background:
The present study was a cross-sectional retrospective study, included one hundred
isolates of S. aureus that were isolated from patients with nosocomial infections. S. aureus isolates
were subjected to full microbiological identification and antibiotics sensitivity testing by the disc
diffusion method. The presence of IEC genes scn, sea, sak, sep, chpwas determined by polymerase
chain reaction (PCR).

Methods:
The current study included 100 S. aureus isolates; 40% were classified as methicillin resistant.
The isolates exhibited marked resistance to beta lactams antibiotics, the lowest resistance
was to erythromycin, ciprofloxacin and vancomycin. The presence of one or more IEC was determined
in 89 isolates. The prevalence of chp, sak, sea, sep and scn was 54%, 53%, 8%, 7% and
30%, respectively.

Results:
S. aureus isolates with IEC genes had increased resistance rates to the studied antibiotics;
however, this increase was statistically insignificant either to beta-lactam antibiotics, such as
amoxacillin/clavulinic acid (P=0.794), ampicillin (P=0.561), cefotaxim (P=0.271), ceftazidime
(P=0.145), imipenem (P=0.589) or non beta-lactam antibiotics, such as amikacin (P=0.955) and
trimethoprim/sulfamethoxazale (P=0.974). From 40 methicillin resistant Staphylococcus aureus
(MRSA) strains, 37 isolates harbor one or more immune evasion cluster genes.

Conclusion:
The high prevalence of these genes among MRSA may explain its pathogenesis.
There is a need for studies with a high number of isolates to verify the present findings.
Herbal Therapy for the Management of Seborrheic Dermatitis: A Narrative Review
Authors: Ayatollahi Azin , Firooz Alireza , Lotfali Ensieh , Mojab Faraz , Fattahi Mahsa 
Published: November 2021

Introduction:
Dandruff and seborrheic dermatitis [SD] are similar skin conditions but have different severities. Because the current therapies are not able to completely remove dandruff, herbal extracts with better effectiveness and fewer side effects are being used in the pharmaceutical and cosmetic industries. Due to the adverse effects of chemical drugs, the use of natural products and traditional medicine has sharply increased over the past few decades. Therefore, in this review, we report herbs used as anti-dandruff agents in traditional medicine around the world.

Methods:
The review was conducted on the literature available on the medicinal utility of certain plants as antidandruff agents using PubMed and Google Scholar and the following search terms: Dandruff and Plants or Medicinal Plant and Dandruff treatment; and Essential oil and Dandruff.

Results:
Because the current therapies are not able to completely remove dandruff, herbal extracts with better effectiveness and fewer side effects are being used in the pharmaceutical and cosmetic industries. Nowadays, there are many different types of herbal antidandruff shampoo. They are effective and safe without the side effects of chemical agents. Recently, a large number of physicians have turned to herbal medicine. Clinical evidence of the therapeutic effects from herbal products has led to the study of many more herbs for their therapeutic roles.

Conclusion:
Herbal are now accepted to act a essential role in the development of favourable therapeutics, either alone or in combination with conventional antibiotics. However, the major challenges to this include finding compounds with satisfactorily lower MICs, low toxicity, and high bioavailability for effective and safe use in humans and animals.
Human population growth and the socioeconomic effects in warri metropolitan city Delta State Nigeria
Authors: Sajini Faith Iwejingi 
Published: November 2021

The observable impact of population growth on socioeconomic life has become a major policy issue, especially in developing countries. This article examines the growth in human population and the socio-economic effects in Warri metropolis, Nigeria, with the specific objectives of establishing the trend in population growth from 1960-2020 using secondary data, highlighting the effects that population growth has on education, employment, and income levels, examining the effects of population growth on the socio-economic life of the inhabitants of Warri metropolis, and to make recommendations. Deriving from percentage investigation of responses, the study found that population growth exerts a considerable impact on education, employment, and income levels in the Warri metropolis. The ANOVA test outcome with p< 0.05 (0.000), led to the rejection of the first null hypothesis and the alternative hypothesis accepted, therefore there is a significant change in population across the period. The post hoc test reveals that the variations however emanated from the period between 1980 -2020. Another finding portrays that, with an R-square value of .639, that population growth expresses about 64% effect on socioeconomic life in the Warri metropolis. The study made policy-relevant recommendations that stem from the findings.
Public perception of crisis in companies
Authors: Jain Suparna , Singh Pavitar Parkash , Lakhanpal Sorabh , Gupta Manish 
Published: November 2021

Crisis is inevitable and in today’s scenario with the pandemic affecting every aspect of our lives, crisis has become something which every industry has had to deal with. The more important aspect today is, how to deal with crisis today. To do so it becomes necessary to understand and evaluate the impact it has on the brand. The study focuses on the impact of crisis on brand image and reputation. The study was conducted amongst the people of Jalandhar with a sample of 130. This study aims at evaluating the relation between a company and it consumers, the way they perceive business news and the manner in which they react to crisis by continuing to support the brand and purchasing.
study on impact of PSL on gross NPAS of nationalised banks: an empirical approach
Authors: Susena Karona Cahya , Huda Miftachul , Maseleno Andino , Sahoo Bibhu Prasad , Kaur Karman 
Published: November 2021

In order to encourage banks to lend more to neglected areas of the economy, the idea of a priority sector was introduced. These priority sectors add significantly to gross domestic product but have not received sufficient finance to function adequately. However, lending in the priority sector is not very warmly welcomed by the banks, particularly nationalized banks in India, as they generate more nonperforming assets than other sectors. It is the priority sector that contributes to the biggest default. As far as NPAs on account lending to the priority sector are concerned, it has been observed that there are inefficiencies in this sector, such that the fresh loans turning bad. Thus, our study examines the impact of non-priority sector loans on the rise of NPAs in the nationalized banks.
Interspeaker variation in the negated perfective aspect of Zamboanga Chavacano
Authors: Eijansantos Abee M. , Alieto Ericson O. , Emmanuel Marjorie S. , Pasoc Marie Grace O. , Bangayan-Manera Alma 
Published: November 2021

Framed from four perspectives, (1) Schütze & Curbach (2019), grammaticality judgment and linguistic methodology; (2) Mcwhorter’s (2011), description of the complexity of creoles as flourishing over time from an original state; (3) Steinkruger (2013), explanation of negated sentences in the perfective aspect; and (4) Lee (2005), delineation of native speakers of a language, this research paper looked into the combination of the negator nohay and the perfective aspect markers ya and yan (ya man) in the sentence. A negated sentence with a perfective aspect is a structure that seems to be accepted by some native speakers of Chavacano (or Chabacano) but rejected by others. In the literature, only Steinkruger (2013), describes the permissibility of the forenamed combination in the syntactic structure of Chavacano. It was hypothesized that such a combination is acceptable in Chavacano and that there is an interspeaker variation pertinent to its acceptability. To confirm these hypotheses, data were collected via grammaticality judgment from 105 native Chavacano speakers and another set of data were collected via interview from 10 native speakers of Chavacano for corroborative purposes.
Inovasi Gerakan Gelar Gulung sebagai Solusi Pemenuhan Kebutuhan Pangan Mandiri di Kota Yogyakarta
Authors: Farida Rahmawati  , Hidayah Ana Chusniatul , Faizah Aida Nur , Falahuddin Ahmad , Okuputra M Adryan 
Published: November 2021

Gerakan Gelar Gulung merupakan aksi tanggap warga dalam hal pemenuhan kebutuhan pangan masyarakat yang terdampak oleh Pandemi COVID-19 di Desa Tegalweru Kecamatan Tegalrejo Kota Yogyakarta. Tujuan penelitian ini adalah mengeksplorasi aksi dan inovasi yang dilakukan Gerakan Gelar Gulung dalam memenuhi kebutuhan pangan secara mandiri sebagai upaya mitigasi dampak pandemi COVID-19. Analisis dalam penelitian ini dilakukan dengan metode deskriptif melalui pengumpulan data-data kualitatif yang diperoleh melalui metode observasi, wawancara, dan kepustakaan. Hasil penelitian menunjukkan bahwa terdapat 5 aksi dalam Gerakan Gelar Gulung yaitu a) aksi mapping warga mandiri pastisipatif, b) aksi tanggap darurat pangan, c) aksi sosial kemandirian ekonomi, d) aksi jejaring pangupa jiwa, dan e) aksi berkebun lumbung pangan. Implementasi Gerakan Gelar Gulung ini mendapatkan respon positif dari berbagai pihak dikarenakan program yang sedang berjalan ini mampu meningkatkan ketahanan pangan dalam masa pandemi COVID-19 dan mendorong kemandirian ekonomi dalam jangka panjang.
Kata kunci: Gerakan Gelar Gulung, Pandemi COVID-19, Ketahanan Pangan

Gelar Gulung is a citizen action in terms of fulfilling the food needs of society who affected by COVID-19pandemic. The purpose of the study is exploring what actions and innovations which were carried out by Gelar Gulung action in fulfilling food needs to mitigate the impact of COVID-19 pandemic, especially in Tegalweru Village. The analysis in this study was done using descriptive methods by collecting qualitative data obtained through observation, interview, and literature study. The results showed that there were 5 actions, namely a) participatory mapping, b) food emergency response actions, c) sufficiency economy, d) community leaders’ network actions, and e) urban farming. The implementation of Gelar Gulung action received positive response from the stakeholders as this ongoing program was able to increase food security during the COVID-19pandemic and encourage long-term economic sufficiency.
Keywords: Gelar Gulung Action, COVID-19 Pandemic, Food Security
Prevalence of comorbidities and its impacts in Hospitalized patients with COVID-19
Authors: Khaksar Mohammad Ali , Zanganeh Yousefabadi Elham , Taleb Zadeh Reza , Rashidi Homeira , Maniati Mahmood , Bakhtiari Nima 
Published: November 2021

Objective: The purpose of this study is to evaluate the prevalence of comorbidities in hospitalized COVID-19 patients and its effects on the severity of the disease. The coronavirus pandemic has been a challenging problem for health care systems since December 2019.
Methods: This was a retrospective, cross-sectional study analyzing data related to the epidemiological characteristics of COVID-19 patients admitted to Razi Hospital in Ahvaz, Iran from November 2020 to February 2021. The data on patient demographic characteristics including age, gender, and underlying diseases were collected from patient records. Patients whose data were unavailable or incomplete were excluded from the study.
Results: The mean age of all of the 730 patients studied was 56.30Â±16.36 years, and 53.7% of them were men. Nearly 40% of the patients reported more than one comorbidity, with diabetes mellitus being the most frequent one (37.5%) followed by hypertension (35.3%) and ischemic heart disease (24.9). In addition, 21.5% of the patients required intensive care unit admission. Finally, 11.9% of the patients had respiratory distress and became intubated, and approximately 13.6% of the patients died. Hyperlipidemia, liver failure, tuberculosis, and elevated inflammatory biomarkers are risk factors for ICU admission and death.
Conclusion: we found that male gender, older age, hyperlipidemia, liver failure, TB, having more than one comorbidity, and elevated inflammatory biomarkers were significantly associated with the risk of severe COVID-19 disease.
Artificial Intelligence Enabled Reagent-free Imaging Hematology Analyzer
Authors: Shu Xin , Sansare Sameera , Jin Di , Zhang Xiangxiang , Tong Kai-Yu , Pandey Rishikesh , Zhou Renjie 
Published: November 2021

Leukocyte differential test is a widely performed clinical procedure for
screening infectious diseases. Existing hematology analyzers require
labor-intensive work and a panel of expensive reagents. Here we report
an artificial-intelligence enabled reagent-free imaging hematology
analyzer (AIRFIHA) modality that can accurately classify subpopulations
of leukocytes with minimal sample preparation. AIRFIHA is realized
through training a two-step residual neural network using label-free
images of isolated leukocytes acquired from a custom-built quantitative
phase microscope. By leveraging the rich information contained in
quantitative phase images, we not only achieved high accuracy in
differentiating B and T lymphocytes, but also classified CD4 and CD8
cells, therefore outperforming the classification accuracy of most
current hematology analyzers. We validated the performance of AIRFIHA in
a randomly selected test set and cross-validated it across all blood
donors. Owing to its easy operation, low cost, and accurate discerning
capability of complex leukocyte subpopulations, we envision AIRFIHA is
clinically translatable and can also be deployed in resource-limited
settings, e.g., during pandemic situations for the rapid screening of
infectious diseases.

Corresponding author(s) Email: rjzhou@cuhk.edu.hk,
rishikesh.pandey@uconn.edu
IS ANTI-SECTARIANISM A DESIDERATUM OF A PUBLIC REASON VIEW?
Authors: Tahzib Collis 
Published: November 2021

AbstractPublic reason liberals hold that laws and institutions must be in some sense justifiable to all reasonable citizens. Public reason liberals have developed different accounts of the constituency of reasonable citizens to whom justification is owed. Recently, a number of theorists have suggested that public reason views with less “sectarian” accounts of reasonableness are in one way better than public reason views with more “sectarian” accounts of reasonableness. Yet despite being used to tremendous effect to motivate particular theories of public reason, this anti-sectarianism desideratum has not received focused treatment, and hardly any detailed arguments have been offered for it. In this paper, I fill this gap by considering the case for the anti-sectarian desideratum. I find that there is no good reason to regard less sectarian public reason views as in one way better than more sectarian views.
Linking Cybersecurity and Accounting: An Event, Impact, Response Framework
Authors: Janvrin Diane J. , Wang Tawei 
Published: November 2021

SYNOPSIS
Due to recent high-profile cybersecurity breaches and increased practitioner and regulatory attention, organizations are under pressure to consider the accounting implications of these attacks and develop appropriate responses. Specifically, cybersecurity events may affect organizations' operations, financial and non-financial performance, and ultimately its stakeholders. To address how cybersecurity issues may affect accounting, this paper presents an Event, Impact, Response Framework to discuss current research and consider implications for both practitioners and researchers. The Framework highlights how practitioners may rely on research findings to better assess cybersecurity threats, understand their impact, and develop response strategies. Results encourage additional research examining how (1) organizations identify cybersecurity threats, incidents, and breaches, (2) cybersecurity affects different risks, and (3) management responses to cybersecurity risks and events. Further, the Framework suggests the need for cybersecurity research to extend beyond the AIS community to areas such as financial accounting, managerial accounting, and auditing.