bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concomitantly discovered visceral artery aneurysms do rarely grow during cancer therapy
Authors: von Rose Aaron Becker , Kobus Kathrin , Bohmann Bianca , Trenner Matthias , Wahida Adam , Eckstein Hans‐Henning , Bassermann Florian , von Heckel Korbinian , Wolk Steffen , Reeps Christian , Schwaiger Benedikt J. , Eilenberg Wolf‐Hans , Neumayer Christoph , Burghuber Christoph , Busch Albert 
Published: November 2021

AbstractVisceral artery aneurysms (VAA) are a rare entity of arterial aneurysms with the imminent threat of rupture. The impact of cancer and chemotherapy on the growth of VAAs is unknown. A retrospective dual center cohort study of patients with concomitant VAA and different types of cancer was conducted and the impact of various chemotherapeutic agents on VAA growth was studied by sequential CT analysis. For comparison, a non‐cancer all comer cohort with VAAs and no cancer was studied to compare different growth rates. The primary endpoint was aneurysm progress or regression >1.75 mm. Chi‐square test, Fisher's exact test and Mann–Whitney test was used for statistical comparison. In the 17‐year‐period from January 2003 to March 2020, 59 patients with 30 splenic artery aneurysms, 14 celiac trunk aneurysms, 11 renal artery aneurysms and 4 other VAA and additional malignancy were identified. 20% of patients suffered from prostate cancer, the rest were heterogeneous. The most prevalent chemotherapies were alkylating agents (23%), antimetabolites (14%) and mitose inhibitors (10%). Eight patients had relevant growth of their VAA and one patient showed diameter regression (average growth rate 0.1 ± 0.5 mm/year). Twenty‐nine patients with 14 splenic, 11 RAAs (seven right) and 4 celiac trunk aneurysms were available in the non‐cancer comparison cohort (average growth rate 0.5 ± 0.9 mm/year, p = 0.058). However, the growth rate of patients receiving operative treatment for relevant VAA growth was significantly higher (p = 0.004). VAAs grow rarely, and rather slow. Cancer and/or chemotherapy do not significantly influence the annual growth rate. Additional control examinations seem unnecessary.
Identifying opportunities to advance health equity in interventional cardiology: Structural heart disease
Authors: Allana Salman S. , Alkhouli Mohamad , Alli Olueseun , Coylewright Megan , Horne Aaron , Ijioma Nkechi , Kadavath Sabeeda , Pineda Andres M. , Sanchez Carlos , Schreiber Theodore L. , Shah Atman P. , Smith Conrad , Suradi Hussam , Sylvia Kristyn E. , Young Michael , Krishnan Sandeep K. 
Published: November 2021

AbstractHealth care practices are influenced by variety of factors. These factors that include social determinants, race and ethnicity, and gender not only affect access to health care but can also affect quality of care and patient outcomes. These are a source of health care disparities. This article acknowledges that these disparities exist in getting optimal care in structural heart disease, reviews the literature and proposes steps that can help reduce these disparities on personal and committee levels.
Insights in a restricted temporary pacemaker strategy in a lean transcatheter aortic valve implantation program
Authors: Hokken Thijmen W. , de Ronde Marjo , Wolff Quinten , Schermers Thom , Ooms Joris F. , van Wiechen Maarten P. , Kardys Isabella , Daemen Joost , de Jaegere Peter P. , Van Mieghem Nicolas M. 
Published: November 2021

AbstractObjectivesTo study the safety and feasibility of a restrictive temporary‐RV‐pacemaker use and to evaluate the need for temporary pacemaker insertion for failed left ventricular (LV) pacing ability (no ventricular capture) or occurrence of high‐degree AV‐blocks mandating continuous pacing.BackgroundVentricular pacing remains an essential part of contemporary transcatheter aortic valve implantation (TAVI). A temporary‐right‐ventricle (RV)‐pacemaker lead is the standard approach for transient pacing during TAVI but requires central venous access.MethodsAn observational registry including 672 patients who underwent TAVI between June 2018 and December 2020. Patients received pacing on the wire when necessary, unless there was a high‐anticipated risk for conduction disturbances post‐TAVI, based on the baseline‐ECG. The follow‐up period was 30 days.ResultsA temporary‐RV‐pacemaker lead (RVP‐cohort) was inserted in 45 patients, pacing on the wire (LVP‐cohort) in 488 patients, and no pacing (NoP‐cohort) in 139 patients. A bailout temporary pacemaker was implanted in 14 patients (10.1%) in the NoP‐cohort and in 24 patients (4.9%) in the LVP‐cohort. One patient in the LVP‐cohort needed an RV‐pacemaker for incomplete ventricular capture. Procedure time was significantly longer in the RVP‐cohort (68 min [IQR 52–88.] vs. 55 min [IQR 44–72] in NoP‐cohort and 55 min [IQR 43–71] in the LVP‐cohort [p < 0.005]). Procedural high‐degree AV‐block occurred most often in the RVP‐cohort (45% vs. 14% in the LVP and 16% in the NoP‐cohort [p ≤ 0.001]). Need for new PPI occurred in 47% in the RVP‐cohort, versus 20% in the NoP‐cohort and 11% in the LVP‐cohort (p ≤ 0.001).ConclusionA restricted RV‐pacemaker strategy is safe and shortens procedure time. The majority of TAVI‐procedures do not require a temporary‐RV‐pacemaker.
Influence of bread‐making method, genotype, and growing location on whole‐wheat bread quality in hard red spring wheat
Authors: Khalid Khairunizah Hazila , Ohm Jae‐Bom , Simsek Senay 
Published: November 2021

AbstractBackground and objectivesExperimental bread‐making is essential in wheat quality evaluation. This research examined three different types of bread‐making methods, sponge‐and‐dough (SpD), straight‐dough (StD), and no‐time dough (NoD) methods, to identify a suitable method to evaluate whole‐wheat flour (WWF) bread‐making quality for diverse hard red spring (HRS) wheat samples.FindingsThe StD method, and to a lesser extent NoD, showed higher variation among WWF samples for bread‐making traits. On the contrary, SpD bread quality traits were more similar among WWF samples. When the StD method was used to evaluate 21 HRS wheat genotypes grown at six locations in North Dakota, most WWF bread‐making quality traits varied significantly among genotypes and growing locations. Specifically, the HRS genotypes showed relatively high variability for the bread loaf volume and symmetry, while growing locations contributed largely to the variability of the baking water absorption.ConclusionsThe StD method was suitable to evaluate the variability of WWF bread‐making quality traits among HRS wheat genotypes grown at various growing locations in North Dakota.Significance and noveltyThe research identified an experimental bread‐making procedure that is useful for the evaluation of the WWF bread‐making quality in HRS wheat breeding programs. The information will help segregate high‐quality HRS genotypes in plant breeding programs.
Beware of the ambiguous enemy of multisystem inflammatory syndrome in adult (MIS‐A) following Covid‐19 infection or vaccination
Authors: Al Bishawi Ahmad , Ali Maisa , Al‐Zubaidi Khaled , Abdelhadi Hamad 
Published: November 2021

AbstractMultisystem Inflammatory Syndrome is a rare and novel clinical presentation described during the evolving COVID‐19 pandemic. The condition is usually presenting as a sepsis‐like syndrome leading to secondary multi‐organ dysfunction post–COVID‐19 infection. Although the syndrome has been mainly described in children, rare adults' form has been similarly described. We are describing a 37‐year‐old female patient presented with fever and neck pain after 1 month of a mild SARS‐CoV‐2 infection course and 10 days post her second COVID‐19 vaccine. Examination demonstrated fever, hypotension, and hypoxemia, in addition to multiple tender cervical lymph nodes. Initial laboratory workup showed evidence of significant inflammation with raised markers, including C‐reactive protein, ferritin, and interleukin‐6. Extensive evaluation to rule out active infection was done, and all return negative, including repeat SARS‐CoV‐2 test. Furthermore, cardiac evaluation showed moderately reduced systolic ventricular function. Despite all negative test and supportive measures, the patient continued to deteriorate requiring critical care admission for ionotropic support, non‐invasive ventilation in addition to presumptive broad‐spectrum antimicrobial management. There was no significant improvement with supportive care until the presentation of multisystem involvement on in the context of a recent history of COVID 19 and negative infective screen was raised. The diagnosis of multisystem inflammatory syndrome‐adult form (MIS‐A) was embraced, and the patient was commenced on methylprednisolone leading to a dramatic resolution of symptoms both clinically and biochemically with stabilization of vital functions allowing for safe outcomes.
Ultrafast Regenerating Spent LiCoO2 Lithium‐Ion Batteries into Bifunctional Electrodes for Rechargeable Zn‐Air Batteries
Authors: Yang Changan , Jin Zhiwei , Zhang Xun , Zheng Xuerong , He Xuanmeng 
Published: November 2021

AbstractThe ever‐increasing use of lithium‐ion batteries (LIB) results in piles of spent batteries, which threats the environment and the supply chain of strategic metals. Developing sustainable recycling strategies for the cathode of spent LIB can bring about promising environmental and economic benefits. In this work, we present an ultrafast high temperature shock process for regenerating typical LiCoO2 (LCO) spent cathodes into the carbon layer/Co3O4 composite (C/CO). The nanosized Co3O4 provides large active sties exposure, while the graphitized carbon layer can potentially enhance the electronic conductivity towards oxygen evolution and oxygen reduction (OER and ORR) catalysis. Benefiting from the enhanced active sties exposure, electronic conductivity, and the synergistic effect between the two domains, the C/CO composite shows efficient bifunctional (OER and ORR) electrocatalytic properties. The OER overpotential (at 10 mA cm−2) and ORR on‐set potential reach 245 mV and 0.90 V, respectively. Moreover, the aqueous rechargeable Zn‐air batteries using C/CO composite as air cathodes display high specific capacity (698 mAh g−1), power density (131 mW cm−2), and as well as cycling stability. This work provides a waste to treasure way that is eco‐friendly, low‐cost, and ultrafast for regenerating the spent LIB for further applications in energy storage systems.
One‐ and Two‐Electron Transfer Oxidation of 1,4‐Disilabenzene with Formation of Stable Radical Cations and Dications
Authors: Chen Yilin , Chen Zhikang , Jiang Liuyin , Li Jiancheng , Zhao Yiling , Zhu Hongping , Roesky Herbert W. 
Published: November 2021

AbstractElectron‐transferable oxidants such as B(C6F5)3/nBuLi, B(C6F5)3/LiB(C6F5)4, B(C6F5)3/LiHBEt3, Al(C6F5)3/(o‐RC6H4)AlH2 (R=N(CMe2CH2)2CH2), B(C6F5)3/AlEt3, Al(C6F5)3, Al(C6F5)3/nBuLi, Al(C6F5)3/AlMe3, (CuC6F5)4, and Ag2SO4, respectively were employed for reactions with (L)2Si2C4(SiMe3)2(C2SiMe3)2 (L=PhC(NtBu)2, 1). The stable radical cation [1]+. was formed and paired with the anions [nBuB(C6F5)3]− (in 2), [B(C6F5)4]− (in 3), [HB(C6F5)3]− (in 4), [EtB(C6F5)3]− (in 5), {[(C6F5)3Al]2(μ‐F)]− (in 6), [nBuAl(C6F5)3]− (in 7), and [Cu(C6F5)2]− (in 8), respectively. The stable dication [1]2+ was also generated with the anions [EtB(C6F5)3]− (9) and [MeAl(C6F5)3]− (10), respectively. In addition, the neutral compound [(L)2Si2C4(SiMe3)2(C2SiMe3)2][μ‐O2S(O)2] (11) was obtained. Compounds 2–11 are characterized by UV‐vis absorption spectroscopy, X‐ray crystallography, and elemental analysis. Compounds 2–8 are analyzed by EPR spectroscopy and compounds 9–11 by NMR spectroscopy. The structure features are discussed on the central Si2C4‐rings of 1, [1]+., [1]2+, and 11, respectively.
Carboboration‐Driven Generation of a Silylium Ion for Vinylic C−F Bond Functionalization by B(C6F5)3 Catalysis
Authors: Yata Tetsuji , Nishimoto Yoshihiro , Yasuda Makoto 
Published: November 2021

AbstractStrong main‐group Lewis acids such as silylium ions are known to effectively promote heterolytic C(sp3)−F bond cleavage. However, carrying out the C(sp2)−F bond transformation of vinylic C−F bonds has remained an unmet challenge. Herein, we describe our development of a new and simple strategy for vinylic C−F bond transformation of α‐fluorostyrenes with silyl ketene acetals catalyzed by B(C6F5)3 under mild conditions. Our theoretical calculations revealed that a stabilized silylium ion, which is generated from silyl ketene acetals by carboboration, cleaves the C−F bond of α‐fluorostyrenes. A comparative study of α‐chloro or bromostyrenes demonstrated that our reaction can be applied only to α‐fluorostyrenes because the strong silicon‐fluorine affinity facilitates an intramolecular interaction of silylium ions with fluorine atom to cleave the C−F bond. A broad range of α‐fluorostyrenes as well as a range of silyl ketene acetals underwent this C−F bond transformation.
Heterogeneous Catalytic Degradation of Diuron Using Algerian Sodium Montmorillonite
Authors: Tlemsani Salima , Taleb Zoubida , Pirault‐Roy Laurence , Taleb Safia 
Published: November 2021

AbstractDiuron is categorized as a probable human carcinogen by the United States Environmental Protection Agency (EPA). This work is aimed to determine the optimal conditions for the catalytic degradation of Diuron in an aqueous solution with H2O2 using Algerian sodium Montmorillonite (Mont‐Na) as the catalyst. The material is characterized before and after the experiment using X‐ray diffraction, Fourier transform infrared (FTIR) spectroscopy, specific surface area (SBET), elemental analysis, and thermal analysis (TGA/DTA). The surface charge is determined by measuring the point of zero charge. Tests with H2O2 without Mont‐Na provide a 32% conversion rate after 8 h. However, a mixture of 1 g Mont‐Na and H2O2 increases the conversion rate to 91% after 180 min at 25 °C and pH 6.3. The Diuron disappearance is evidenced by high‐performance liquid chromatography using a UV–vis detector (HPLC/UV–vis). Specifically, 3,4‐dichloroaniline (DCA) is the only by‐product. At the basic pH values 9 and 11, a conversion rate of 72.5% is achieved with a lower contact time of 150 min. A change in temperature toward higher values results in a decrease in the degradation rate. Overall, Algerian sodium Montmorillonite is used successfully for the heterogeneous catalytic degradation of Diuron from polluted water.
Regression analysis‐based identification model of key impactful parameters on buried antennas
Authors: El Mejjatti Mounir , Habbani Ahmed , El Bouanani Faissal 
Published: November 2021

SummaryThe antenna's bandwidth is strongly dependent on its physical properties and the environment where it is located. Nevertheless, for transmitting devices embedded permanently in the soil, the propagation medium's properties are unstable due to dielectric permittivity's spatial and temporal changes. Relying on soil parameters values, we present three new multivariable regression models allowing a good fit to the dataset curves with antenna's resonant frequency variations prediction of about 98%. Precisely, such models have been obtained with the help of the multiple linear regression analysis method. Additionally, the results revealed that amongst four considered parameters (i.e., volumetric moisture, bulk density, specific density, and temperature), volumetric moisture is the most influencing factor on the antenna operating frequency band with a correlation coefficient of −0.989, whereas it equals 0.04, −0.035, and −0.002 for the temperature, bulk density, and specific density, respectively.
Return of the lysergamides. Part VII: Analytical and behavioural characterization of 1‐valeroyl‐d‐lysergic acid diethylamide (1V‐LSD)
Authors: Brandt Simon D. , Kavanagh Pierce V. , Westphal Folker , Pulver Benedikt , Morton Kathleen , Stratford Alexander , Dowling Geraldine , Halberstadt Adam L. 
Published: November 2021

AbstractThe psychopharmacological properties of the psychedelic drug lysergic acid diethylamide (LSD) have attracted the interest of several generations of scientists. While further explorations involving novel LSD‐type compounds are needed to assess their potential as medicinal drugs, the emergence of novel derivatives as recreational drugs has also been observed. 1‐Valeroyl‐LSD (also known as 1‐valeryl‐LSD, 1‐pentanoyl‐LSD, 1V‐LSD, or “Valerie”) is a new N1‐acylated LSD derivative that recently appeared on the online market, and it could be viewed as a higher homolog of ALD‐52, 1P‐LSD, and 1B‐LSD. The present study included the analytical characterization and involved various methods of mass spectrometry (MS), gas and liquid chromatography (GC and LC), nuclear magnetic resonance (NMR) spectroscopy, GC–solid‐state infrared (GC‐sIR) analysis, and Raman spectroscopy. The in vivo activity of 1V‐LSD was assessed using the mouse head‐twitch response (HTR), a 5‐HT2A‐mediated head movement that serves as a behavioral proxy in rodents for human hallucinogenic effects. Similar to LSD and other psychedelic drugs, the HTR induced by 1V‐LSD was dose dependent, and the median effective dose for 1V‐LSD was 373 nmol/kg, which was about a third of the potency of LSD (ED50 = 132.8 nmol/kg). Lysergamides containing the N1‐substituent typically act as weak partial agonists at the 5‐HT2A receptor and are believed to serve as prodrugs for LSD. 1V‐LSD is also likely to be hydrolyzed to LSD and serve as a prodrug, but studies to assess the biotransformation and receptor pharmacology of 1V‐LSD should be performed to fully elucidate its mechanism of action.
Metabarcoding hyperdiverse kelp holdfast communities on temperate reefs: An experimental approach to inform future studies
Authors: Arranz Vanessa , Liggins Libby , Aguirre J. David 
Published: November 2021

AbstractClassical taxonomic approaches to quantifying biodiversity can be notoriously laborious and restrictive. Instead, molecular metabarcoding is emerging as a rapid, high‐throughput, and cost‐effective tool to catalog biodiversity. Despite the appeal of metabarcoding, methodological and procedural biases must be understood before robust biodiversity inferences can be made. Here, we use CO1 metabarcoding to characterize marine eukaryote communities associated withEcklonia radiata, the dominant eco‐engineering kelp of temperate Australasia. To establish a standardized and reproducible community metabarcoding protocol, we examined the influence of different sample preparation, laboratory, and bioinformatic steps on inferences of species richness and composition of communities associated withE. radiataholdfasts (the root‐like structure anchoring the kelp to the substratum) sampled from northeastern New Zealand. Specifically, we examined the effect of sieving the community into different size fractions and the replicability of results across DNA extractions, polymerase chain reactions and sequencing. Overall, we found that sieving the community into two size fractions before DNA extraction enabled detection of a greater diversity of taxa than not sieving samples. When compared with traditional morphology‐based inventories of kelp holdfast biodiversity, we found that although the taxonomic precision of our metabarcoding approach at the species and genus level was limited by the availability of reference sequences in public repositories, we recovered ~40% more taxa and a greater taxonomic breadth of organisms than morphological surveys (e.g., 18 phyla as compared with 14 phyla). On the basis of our findings, we provide methodological guidelines for the use of metabarcoding as a tool for surveying and monitoring the hyperdiverse species assemblages associated with kelp holdfasts.
State‐of‐the‐art brief review on sanding problem of offshore natural gas hydrates sediments
Authors: Song Jinze , Fu Jianhuang , Xiong Youming , Pang Weixin , He Yufa , Liu Liming , Huang Ting , Liu Chang , Li Yuhao , Li Jianzhuang 
Published: November 2021

AbstractAs the natural gas hydrate (NGH) resources show a bright future, more and more commercial and technical focuses have been devoted to this area. The low productivity, the sanding problem, and the poor economic performance are vital problems hindering the long‐term commercial exploration and development of NGS sediments. Among all these problems, the sanding problem can aggravate the low productivity and the poor economic efficiency problems. Therefore, it is necessary to investigate and tackle the sanding problem for the safe, long‐term, and large‐scale commercial development of offshore NGH resources. The sanding problem of the NGH sediment is highly related to the mechanical behavior of sediment. The main influencing factors are discussed, which are hydrate saturation, effective confining pressure, sand content, hydrate distribution, and multiple‐physical fields. This article summarizes the current research achievements systematically to determine how these factors affect sand production in NGH sediments. Besides the macrolevel about mechanical behaviors of NGH sediment, the sand motion modeling is also included in this review. The source of sand production is the free‐moving sand which comes from formation deformation. The review compares most commonly used yield criteria and then recommends a proper one for NGH sediments. The paper subsequently discusses the common investigation methods for the sanding problem in this area, including numerical simulation and experiments. The design and effect of sand control techniques have also been reviewed and discussed. According to the review results, the paper concludes the current research drawbacks and generates suggestions for future research. The novel methods of sand control investigation are machine learning and optimization methods.
Coastal erosion and sediment reworking caused by hurricane Irma – implications for storm impact on low‐lying tropical islands
Authors: Spiske Michaela , Pilarczyk Jessica E. , Mitchell Stephen , Halley Robert B. , Otai Tiffany 
Published: November 2021

AbstractHurricane Irma (September 2017) was one of the most devastating hurricanes in recent times. In January 2018, a post‐hurricane field survey was conducted on Anegada (British Virgin Islands) to report on the erosional and depositional evidence caused by Hurricane Irma's storm surge and waves. We document the type and extent of hurricane‐induced geomorphological changes, allowing for an improved risk assessment of hurricane‐related inundation on low‐lying islands and carbonate platforms.Anegada's north shore was most impacted by Hurricane Irma. The surge reached about 3.8 m above sea level and onshore flow depths ranged between 1.2 to 1.6 m. Storm wave action created 1 to 1.5 m high erosional scarps along the beaches, and the coastline locally retreated by 6 to 8 m.Onshore sand sheets reached up to 40 m inland, overlie a sharp erosive contact and have thicknesses of 7 to 35 cm along the north shore. In contrast, lobate overwash fans in the south are 2 to 10 cm thick and reach 10 to 30 m inland.Moreover, the hurricane reworked a pre‐existing coast‐parallel coral rubble ridge on the central north shore. The crest of the coral rubble ridge shifted up to 10 m inland due to the landward transport of cobbles and boulders (maximum size 0.5 m3) that were part of the pre‐hurricane ridge.A re‐survey, 18 months after the event, assessed the degree of the natural coastal recovery. The sand along the northern shoreline of Anegada that was eroded during the hurricane and stored in the shallow water, acted as a nearshore source for beach reconstruction which set in only days after the event. Beach recovery peaked in February 2018, when beaches accreted within hours during a nor'easter‐like storm that transported large volumes of nearshore sand back onto the beach.