bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fast occlusion-based point cloud exploration
Authors: Radwan Mohamed , Ohrhallinger Stefan , Wimmer Michael 
Published: July 2021

AbstractLarge-scale unstructured point cloud scenes can be quickly visualized without prior reconstruction by utilizing levels-of-detail structures to load an appropriate subset from out-of-core storage for rendering the current view. However, as soon as we need structures within the point cloud, e.g., for interactions between objects, the construction of state-of-the-art data structures requires O(NlogN) time for N points, which is not feasible in real time for millions of points that are possibly updated in each frame. Therefore, we propose to use a surface representation structure which trades off the (here negligible) disadvantage of single-frame use for both output-dominated and near-linear construction time in practice, exploiting the inherent 2D property of sampled surfaces in 3D. This structure tightly encompasses the assumed surface of unstructured points in a set of bounding depth intervals for each cell of a discrete 2D grid. The sorted depth samples in the structure permit fast surface queries, and on top of that an occlusion graph for the scene comes almost for free. This graph enables novel real-time user operations such as revealing partially occluded objects, or scrolling through layers of occluding objects, e.g., walls in a building. As an example application we showcase a 3D scene exploration framework that enables fast, more sophisticated interactions with point clouds rendered in real time.
Training status affects between-protocols differences in the assessment of maximal aerobic velocity
Authors: Riboli Andrea , Rampichini Susanna , Cè Emiliano , Limonta Eloisa , Borrelli Marta , Coratella Giuseppe , Esposito Fabio 
Published: July 2021

Abstract
Purpose
Continuous incremental protocols (CP) may misestimate the maximum aerobic velocity (Vmax) due to increases in running speed faster than cardiorespiratory/metabolic adjustments. A higher aerobic capacity may mitigate this issue due to faster pulmonary oxygen uptake ($$\dot{V}$$

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O2) kinetics. Therefore, this study aimed to compare three different protocols to assess Vmax in athletes with higher or lower training status.

Methods
Sixteen well-trained runners were classified according to higher (HI) or lower (LO) $$\dot{V}$$

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O2max$$\dot{V}$$

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O2-kinetics was calculated across four 5-min running bouts at 10 km·h−1. Two CPs [1 km·h−1 per min (CP1) and 1 km·h−1 every 2-min (CP2)] were performed to determine Vmax$$\dot{V}$$

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O2max, lactate-threshold and submaximal $$\dot{V}$$

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O2/velocity relationship. Results were compared to the discontinuous incremental protocol (DP).

Results
Vmax, $$\dot{V}$$

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O2max, $$\dot{V}$$

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CO2 and VE were higher [(P < 0.05,(ES:0.22/2.59)] in HI than in LO. $$\dot{V}$$

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O2-kinetics was faster [P < 0.05,(ES:-2.74/ − 1.76)] in HI than in LO. $$\dot{V}$$

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O2/velocity slope was lower in HI than in LO [(P < 0.05,(ES:-1.63/ − 0.18)]. Vmax and $$\dot{V}$$

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O2/velocity slope were CP1 > CP2 = DP for HI and CP1 > CP2 > DP for LO. A lower [P < 0.05,(ES:0.53/0.75)] Vmax-difference for both CP1 and CP2 vs DP was found in HI than in LO. Vmax-differences in CP1 vs DP showed a large inverse correlation with Vmax, $$\dot{V}$$

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O2max and lactate-threshold and a very large correlation with $$\dot{V}$$

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O2-kinetics.

Conclusions
Higher aerobic training status witnessed by faster $$\dot{V}$$

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O2 kinetics led to lower between-protocol Vmax differences, particularly between CP2 vs DP. Faster kinetics may minimize the mismatch issues between metabolic and mechanical power that may occur in CP. This should be considered for exercise prescription at different percentages of Vmax.
Seasonal variations in bird selection pressure on prey colouration
Authors: Zvereva Elena L. , Kozlov Mikhail V. 
Published: July 2021

AbstractThe direction and strength of selection for prey colouration by predators vary in space and time and depend on the composition of the predator community. We tested the hypothesis that bird selection pressure on prey colouration changes through the season due to changes in the proportion of naïve juvenile individuals in the bird community, because naïve and educated birds differ in their responses to prey colours. Bird predation on caterpillar-shaped plasticine models in two boreal forest sites increased sevenfold from early summer to mid-summer, and the time of this increase coincides with the fledging of juvenile birds. In early summer, cryptic (black and green) models were attacked at fivefold higher rates compared with conspicuous (red and yellow) models. By contrast, starting from fledging time, cryptic and conspicuous models were attacked at similar rates, hinting at a lower selectivity by naïve juvenile birds compared with educated adult birds. Cryptic models exposed in a group together with conspicuous models were attacked by birds at a threefold lower rate than cryptic models exposed singly, thus supporting the aposematic commensalism hypothesis. However, this effect was not observed in mid- and late summer, presumably due to the lack of avoidance of conspicuous prey by the juvenile birds. We conclude that selection pressure on prey colouration weakens considerably when naïve birds dominate in the community, because the survival advantages of aposematic colouration are temporarily lost for both the conspicuous and their neighbouring cryptic prey.
A machine learning-based approach to identify unlawful practices in online terms of service: analysis, implementation and evaluation
Authors: Guarino Alfonso , Lettieri Nicola , Malandrino Delfina , Zaccagnino Rocco 
Published: July 2021

AbstractTerms of Service (ToS) are fundamental factors in the creation of physical as well as online legally relevant relationships. They not only define mutual rights and obligations but also inform users about contract key issues that, in online settings, span from liability limitations to data management and processing conditions. Despite their crucial role, however, ToS are often neglected by users that frequently accept without even reading what they agree upon, representing a critical issue when there exist potentially unfair clauses. To enhance users’ awareness and uphold legal safeguards, we first propose a definition of ToS unfairness based on a novel unfairness measure computed counting the unfair clauses contained in a ToS, and therefore, weighted according to their direct impact on the customers concrete interests. Secondly, we introduce a novel machine learning-based approach to classify ToS clauses, represented by using sentence embedding, in different categories classes and fairness levels. Results of a test involving well-known machine learning models show that Support Vector Machine is able to classify clauses into categories with a F1-score of 86% outperforming state-of-the-art methods, while Random Forest is able to classify clauses into fairness levels with a F1-score of 81%. With the final goal of making terms of service more readable and understandable, we embedded this approach into ToSware, a prototype of a Google Chrome extension. An evaluation study was performed to measure ToSware effectiveness, efficiency, and the overall users’ satisfaction when interacting with it.
Herbaceous Layer Net Primary Production of Oak-Hornbeam Forest: Comparing Six Methods of Assessment Based on the Seasonal Dynamics of Biomass Increments
Authors: Rawlik Mateusz , Jagodziński Andrzej M. 
Published: July 2021

AbstractProper estimation of the herb layer annual net primary production (ANPP) can help to appreciate the role of this layer in carbon assimilation and nutrient cycling. Simple methods of ANPP estimation often understate its value. More accurate methods take into account biomass increments of individual species but are more laborious. We conducted our study in an oak-hornbeam forest (site area 12 ha) dominated by beech in NW Poland during two growing seasons (2010 and 2011). We collected herb layer biomass from 7 to 10 square frames (0.6 × 0.6 m). We collected plant biomass every week in April and May and every two weeks for the rest of the growing season. We compared six methods of calculating ANPP. The highest current-year standing biomass (1st method of ANPP calculation) was obtained on May 15, 2010—37.8 g m−2 and May 7, 2011—41.0 g m−2. The highest values of ANPP were obtained by the 6th method based on the sum of the highest products of shoot biomass and density for individual species: 74.3 g m−2 year−1 in 2010 and 94.0 g m−2 year−1 in 2011. The spring ephemeral Anemone nemorosa had the highest share of ANPP with 50% of the total ANPP. Two summer-greens, Galeobdolon luteum and Galium odoratum, each had a ca. 10% share of ANPP. The best results of ANPP calculation resulted from laborious tracking of dynamics of biomass and density of individual shoots.
Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson’s disease: a pilot study
Authors: Yoritaka Asako , Kobayashi Yasuko , Hayashi Tetsuo , Saiki Shinji , Hattori Nobutaka 
Published: July 2021

Abstract

Background
Oxidative stress is involved in the progression of Parkinson’s disease (PD). Recent studies have confirmed that molecular hydrogen (H2) functions as a highly effective antioxidant in animal models of PD. A placebo-controlled, randomized, double-blind, parallel-group clinical pilot study was conducted to assess the efficacy of hydrogen gas inhalation in Japanese patients with PD on treatment with levodopa.

Methods
Twenty participants fulfilling the Movement Disorder Society criteria were enrolled. Participants inhaled 6.5 (0.1) vol% hydrogen gas in 2 L/min of mixed air or placebo air for 16 weeks, twice a day for 1 h.

Results
Five participants were excluded due to deviation from the protocol of the total duration of inhalation < 112 h. No significant differences were seen in the change in the total Movement Disorder Society Unified Parkinson’s Disease Rating Scale score from baseline to the 16th week between the group that inhaled hydrogen gas and the group that inhaled placebo air (Mann–Whitney U test, p > 0.05). No adverse events were seen. The compliance to the protocol-based duration of inhalation time in all participants decreased with the elderly participants, the higher daily dose of levodopa, and the higher PDQ-39 items on emotions (n = 20, p < 0.05).

Conclusion
This pilot study revealed that the inhalation of molecular hydrogen gas was safe, but did not show any beneficial effects in patients with PD.
Trial registration: UMIN ID: 000,039,217 (October 6, 2018)
Construction and demolition waste management in Korea: recycled aggregate and its application
Authors: Kim Jeonghyun 
Published: July 2021

AbstractConstruction and demolition waste generated in the Republic of Korea accounts for about half of the annual waste. The generation of construction waste is expected to increase gradually due to obsolete structures and reconstructions that have reached the end of their service life. Considering the geographical characteristics of Korea, where the land area is small and about 70% of which is mountainous, landfilling of waste is absolutely limited. Therefore, resource circulation such as recycling of construction waste is an urgent and important task. This paper overviews the current status of construction waste generation, treatment, and the flow of government policies in Korea. Furthermore, the current status, limitations, and stakeholder efforts regarding recycling of recycled aggregate from construction waste were reviewed. Data used in this paper were mostly collected from government reports, construction waste regulations, and research papers. The results show that construction waste management systems have been enacted and revised in line with social needs, and each stakeholder is making an effort to use the construction waste practically. The findings can provide valuable examples for countries that lack construction waste management systems.
Graphic abstract
Saving energy in China’s industry with a focus on electricity: a review of opportunities, potentials and environmental benefits
Authors: Yue Hui , Worrell Ernst , Crijns-Graus Wina , Liu Wen , Zhang Shaohui 
Published: July 2021

AbstractIndustry is the largest electricity consuming sector in the world. China consumes about 25% of global electricity demand, and 69% of this is used in industries. The high electricity demand in industry is responsible for 45% of CO2, 25% of SO2, 34% of NOx and 14% of PM emissions in China. This study aims to fill the knowledge gap on the potential for electricity savings in China’s industries, thereby providing important implications for the potential of reducing emissions in electricity-intensive industrial subsectors in general. Available studies are reviewed and compared to identify electricity-saving potentials. The findings show that China’s industrial energy system is shifting to higher electricity and relatively lower fossil fuel use due to accelerated end-use electrification. China’s industry can reduce electricity use by 7–24% in 2040, compared to baseline levels, and generate emission reductions of 192–1118 Mt-CO2, 385–2241 kt-SO2, 406–2362 kt-NOx and 92–534 kt-PM2.5. The iron & steel subsector has the largest contribution to the industrial electricity savings, followed by non-ferrous metals, chemicals, cement and pulp & paper. Policies that combine environmental targets, demand-side efficiency and supply-side retrofits in the power sector should be adopted. Given the different performance of policies in terms of energy savings and emission reduction, sector- and region-specific policies would be preferred.
Adoption of digital technologies and backshoring decisions: is there a link?
Authors: Kamp Bart , Gibaja Juan José 
Published: July 2021

AbstractThe present paper assesses whether the adoption of Industry 4.0 technologies can be related to backshoring. It does so by -firstly- investigating the implementation of such technologies by industrial firms with foreign production plants, the experiences and intentions of these firms regarding the location of production activities, and -secondly- by analyzing backshoring cases among them.It finds that backshoring is a rare phenomenon, and it is questionable whether there is a correlation, left alone causality, between the adoption of digital technologies in home-based manufacturing sites and backshoring hitherto. And while the future may hold more backshoring movements in store, they may not be primarily due to the adoption of Industry 4.0 technologies at home-based plants. Instead, other (foreign) location-specific factors seem to have greater weight in the decision-making processes around backshoring operations. I.e., deteriorating sales forecasts in offshore places where firms have production activities, increases in institutional uncertainty in such places, rationalization of global production apparatuses, and/or a lack of possibilities to deploy foreign manufacturing activities and output for third markets. Also against the backdrop of events like the outbreak of Covid19 and the uncertainty-raising effect it has on international business, the trade-off between producing off-shore or bringing manufacturing activities back home is not likely to depend on technology adoption levels at home and abroad either.
The Clinical Characteristics and Prognosis of Chinese Patients with Light-Chain Amyloidosis: A Retrospective Multicenter Analysis
Authors: He Donghua , Guan Fangshu , Hu Minli , Zheng Gaofeng , He Jingsong , Han Xiaoyan , Yang Yang , Hong Pan , Wang Gang , Zhao Yi , Wu Wenjun , Cai Zhen 
Published: July 2021

AbstractTo retrospectively identify the critical characteristics and prognostic factors of light-chain amyloidosis. Patients and Methods: Data were collected and compared from 91 patients who were diagnosed with light-chain amyloidosis at four hospitals between January 2010 and November 2018. We analyzed the clinical characteristics and performed an overall survival (OS) analysis. Results: Patients (median age, 60 years) were diagnosed with organ involvement of the kidney (91.2%), heart (56%), liver (14.3%), soft tissue (18.7%), or gastrointestinal tract (15.4%), and 68.1% of patients had more than two organs involved. Patients were most treated with bortezomib-based regimens (56%), and only one patient had autologous stem cell transplantation (auto-ASCT). The median OS was 36.33 months and was influenced by the ECOG score, renal involvement, cardiac involvement, hepatic involvement, and persistence of positive immunofixation. Patients who received bortezomib-based treatment had a trend of favorable OS compared to those who received non-bortezomib-based treatments, but the difference was not statistically significant. Although the overall number of organs involved was not related to OS, the number of organs involved in the heart, liver and kidney was related. Multivariate analysis indicated that cardiac involvement and negative hematologic response with persistence of positive immunofixation were independent prognostic factors for OS. Conclusion: Cardiac involvement and the hematologic response to treatment were independent prognostic factors for OS in light-chain amyloidosis patients.
Representation in measurement
Authors: Vessonen Elina 
Published: July 2021

AbstractThe Representational Theory of Measurement (RTM) is the best known account of the kind of representation measurement requires. However, RTM has been challenged from various angles, with critics claiming e.g. that RTM fails to account for actual measurement practice and that it is ambiguous about the nature of measurable attributes. In this paper I use the critical literature on RTM to formulate Representation Minimalism – a characterization of what measurement-relevant representation requires at the minimum. I argue that Representation Minimalism avoids the main problems with RTM while acknowledging its usefulness as the formal foundation of representation in measurement.
Reactivity in measuring depression
Authors: Runhardt Rosa W. 
Published: July 2021

AbstractIf a human subject knows they are being measured, this knowledge may affect their attitudes and behaviour to such an extent that it affects the measurement results as well. This broad range of effects is shared under the term ‘reactivity’. Although reactivity is often seen by methodologists as a problem to overcome, in this paper I argue that some quite extreme reactive changes may be legitimate, as long as we are measuring phenomena that are not simple biological regularities. Legitimate reactivity is reactivity which does not undermine the accuracy of a measure; I show that if such reactivity were corrected for, this would unjustifiably ignore the authority of the research subject. Applying this argument to the measurement of depression, I show that under the most commonly accepted models of depression there is room for legitimate reactivity. In the first part of the paper, I provide an inventory of the different types of reactivity that exist in the literature, as well as the different types of phenomena that one could measure. In the second part, I apply my argument to the measurement of depression with the PHQ-9 survey. I argue that depending on what kind of phenomenon we consider depression to be (a disease, a social construction, a harmful dysfunction, or a practical kind), we will accept different kinds of reactivity. I show that both under the harmful dysfunction model and the practical kinds model, certain reactive changes in measuring depression are best seen as legitimate recharacterizations of the underlying phenomenon, and define what legitimate means in this context. I conclude that in both models, biological aspects constrain characterization, but the models are not so strict that only one concept is acceptable, leaving room for reactivity.
Low efficiency of leucocyte plugging-based drug delivery to cancer in mice
Authors: Qian Baifeng , Termer Andreas , Sommer Christof M. , Mehrabi Arianeb , Ryschich Eduard 
Published: July 2021

AbstractCells of the immune system were proposed for use as Trojan horse for tumour-specific drug delivery. The efficacy of such cell-based drug delivery depends on the site-specific cell homing. This present study was aimed to investigate the potential of leucocytes for intratumoural site-specific enrichment using a locoregional application route in experimental liver tumours. Human neutrophils were isolated from peripheral blood and directly labelled with calcein AM or loaded with doxorubicin. The neutrophil loading and release of doxorubicin and the migration and adhesion to ICAM-1 were analysed in vitro. Macrophages were isolated and activated in vitro. Leucocyte plugging and the distribution pattern in the liver microvasculature were studied ex vivo, and the efficacy of leucocyte plugging in tumour blood vessels was analysed in vivo after superselective intra-arterial injection in mouse liver tumour models. Neutrophils were characterised by the high dose-dependent uptake and rapid release of doxorubicin. Doxorubicin loading did not affect neutrophil migration function. Neutrophil plugging in liver microvasculature was very high (> 90%), both after ex vivo perfusion and after injection in vivo. However, neutrophils as well as activated macrophages plugged insufficiently in tumour blood vessels and passed through the tumour microvasculture with a very low sequestration rate in vivo. Neutrophils possess several properties to function as potentially effective drug carriers; however, the tumour site-specific drug delivery after selective locoregional injection was observed to be insufficient owing to low intratumoural microvascular plugging.Graphical abstract
Aspiring to higher education in regional and remote Australia: the diverse emotional and material realities shaping young people’s futures
Authors: Gibson Skye , Patfield Sally , Gore Jennifer M. , Fray Leanne 
Published: July 2021

AbstractStudents from regional and remote areas remain significantly under-represented in higher education despite decades of equity policy designed to encourage participation. One explanation is that policy initiatives often overlook the realities in local rural contexts that can make higher education less desirable. Applying the theoretical lens of ‘doxic’ and ‘habituated’ aspirations, this paper analyzes interviews with 13 students, 10 parents/carers, and 4 teachers from one regional and one remote community in NSW, Australia. We document the emotional and material realities shaping young people’s imagined futures in these communities, highlighting the commitment to a rural lifestyle in one, and the desire to escape the other community in decline. We argue that developing successful initiatives to address equitable participation in higher education requires a departure from hegemonic discourses of ‘rurality’ and greater recognition of and respect for the diverse needs and desires of regional and remote students.