bluuebunny/crossref_metadata_2025_split huggingface dataset:
The mental health impact of climate change on Pacific Islanders: A systematic review focused on sea level rise and extreme weather events
Authors: Mengesha Netsanet Ayele , Sarnyai Zoltan 
Published: January 2025

Objective This systematic review investigates the impact of climate change on the mental health of Pacific Island Nations (PINs), with a focus on identifying culturally tailored interventions and appropriate research methodologies to address these impacts. Method A systematic review of peer-reviewed literature up to May 18, 2024, was conducted using the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) protocol and the Population, Interest Area, and Context (PICo) framework. Empirical studies on the impact of climate change on mental health in PINs were evaluated by using the Quality Assessment Tool for Studies with Diverse Designs (QATSDD). Results Six studies from the Solomon Islands, Cook Islands, and Tuvalu were identified, indicating significant mental health impacts from sea level rise (SLR) and extreme weather events with compounding and mitigating effects across diverse groups. The Skills for Life Adjustment and Resilience (SOLAR) program was highlighted as a promising culturally adapted intervention. Conclusion Climate change significantly impacts mental health, particularly in PIN communities facing SLR and Extreme Weather Events (EWE). Culturally sensitive interventions, local knowledge, and further research are vital to mitigate these effects and support well-being.
Trademarks and Entrepreneurial Firm Success: Theory and Evidence from Venture Capital Investments in Private Firms
Authors: Bayar Onur , Chemmanur Thomas J. , Rajaiya Harshit , Tian Xuan , Yu Qianqian 
Published: January 2025

We theoretically model an entrepreneur’s choice of his firm’s products to trademark, the relation between the number of trademarks and venture capital (VC) investment staging, long-run operating performance, and successful firm exit probability. We test model predictions using a large dataset of trademarks registered by VC-backed private US firms. We find that firms with a larger number of trademarks at first VC investment have a smaller number of VC financing rounds; have larger long-run sales and employment; and have greater probabilities of successful exit (initial public offering [IPO] or acquisition). Our instrumental variable analysis demonstrates that more trademarks causally enhance firm performance and reduce VC staging. JEL code: G23, G24, L26, O34
Epidemiological Features of Sinonasal Adenocarcinoma and Prognostic Nomogram: A Study Based on the SEER Database
Authors: Yang Lu , Gu Yufeng , Yu Lei , Zhou Qiang , Liu Li , Mao Ying , Ma Ji , Li Yong , Li Na 
Published: January 2025

Objective Our study aimed to update demographic profiles of sinonasal adenocarcinoma (SNAC) between 2000 and 2020, identify independent prognostic risk factors, and devise a predictive nomogram for overall survival (OS). Methods Utilizing the Surveillance, Epidemiology, and End Results (SEER) database, cases of SNAC from 2000 to 2020 were analyzed for incidence trends. Univariate and multivariate Cox regression models helped pinpoint factors impacting patient survival. A prognostic nomogram was then created based on these factors and assessed via concordance index, ROC analysis, and calibration curves. Results Analysis of 488 SNAC patients indicated a rising incidence, peaking among 60-69-year-olds, with a male predominance and the highest occurrence in White populations. Common sites of occurrence included the nasal cavity, and the maxillary and ethmoid sinuses. The nomogram, developed with 184 patients, highlighted older age (≥70), male sex, advanced T stages (T4b, T4a), distant metastasis, larger tumors (≥5 cm), and lack of surgery as poor prognostic indicators. Nomogram performance demonstrated strong predictive capabilities in both training and validation cohorts. Conclusion This investigation, leveraging the SEER database, elucidates the epidemiology of SNAC and pinpoints key adverse prognostic determinants: age ≥70, male gender, T stages T4b and T4a, presence of distant metastasis, tumor size exceeding 5 cm, and absence of surgical intervention. Moreover, it introduces a novel nomogram capable of accurately forecasting 1-, 3-, and 5-year OS for SNAC patients, thereby enhancing disease comprehension and facilitating the formulation of tailored therapeutic strategies by clinicians.
Preliminary efficacy and safety results of a new macular buckle model (NPB®) in myopic traction maculopathy
Authors: Viana Ana Rita , Ripa Matteo , Silva André , Matello Veronika , Parolini Barbara 
Published: January 2025

Purpose To describe the efficacy and safety outcomes of NPB® macular buckle (MB) in myopic traction maculopathy (MTM). Methods A monocentric, prospective cohort study of the naïve eyes who underwent MB surgery, alone or combined with pars plana vitrectomy (PPV) for MTM, using the new NPB® buckle, between December 2022 and June 2024. The anatomical results, postoperative complications, and MB ease of use were analyzed as the main outcomes. Secondary outcomes included changes in best-corrected visual acuity (BCVA), axial length (AL), and intraocular pressure (IOP). Results Forty eyes of 39 patients were included, 34 (85%) were female. MB implantation alone was performed in 32 eyes (80%) and combined surgery in 8 (20%). At the final visit, 22 eyes (56,4%) “resolved” and 17 (43,6%) “improved” their retinal status, and 26 eyes (66,7%) “resolved”, 8 (20,5%) “improved” and 5 (12,8%) “unchanged” their foveal status. Thirteen (32,5%) had repositioning surgery mainly due to MB decentration. Early complications (month 1) included diplopia in 3 eyes (7,5%) and elevation deficit without diplopia in 2 (5,0%). Late complications (month 6) involved mild buckle exposure in 3 cases (7,5%). No cases required MB removal or additional PPV. BCVA improved from 0,61 ± 0,35 to 0,49 ± 0,38 logMAR ( p = 0,013), AL changed from 31,5 ± 2,2 to 30,0 ± 2,2 mm ( p < 0,001), and IOP changed from 16,0 ± 2,7 to 14,5 ± 3,3 mmHg ( p = 0,013), between the baseline and the final visit. Conclusions The new MB model is an effective and safe technique for MTM treatment as a first-line strategy, alone or in combination with PPV.
The relation between estimated pulse wave velocity and peripheral arterial disease: A study based on NHANES
Authors: Ning Meiling , Jiang Xuehe , Jia Shuang , Cui Na , Yu Limei 
Published: January 2025

Background As a type of atherosclerotic lesion affecting the peripheral vascular system, peripheral arterial disease (PAD) has an elevated disability rate and seriously affects patients’ quality of life. Estimated pulse wave velocity (ePWV) is an alternative indicator of pulse wave velocity and is closely linked with atherosclerosis. However, the link between ePWV and PAD is unelucidated. Objectives This research was undertaken to dissect the linkage between ePWV and PAD. Methods This project enrolled 6250 participants in the NHANES between 1999 and 2004. The linkage between ePWV and PAD and its possible influencing factors were explored by constructing a weighted logistics regression model and subgroup analysis. In addition, the threshold effect analysis and restricted cubic spline (RCS) model were utilized to evaluate the non-linear link. Results The weighted logistic regression model demonstrated a great positive linkage between ePWV and PAD risk in the fully adjusted model (OR = 1.29, 95% CI: 1.18–1.42, p < .001). There was a significant nonlinear link between ePWV and PAD. When ePWV was higher than 9.297, the risk of PAD increased significantly (OR = 1.03, 95% CI: 1.02–1.04, p < .001). No significant linkage was detected when the value was below this threshold. Additionally, the subgroup analysis further demonstrated that ePWV had a stronger positive link with PAD in the elderly population (age ≥60 years) and in people with BMI ≤30. Conclusion ePWV is an effective predictor of PAD risk especially in the elderly and non-obese population.
How Can Non-Hospital Surgical Centres Improve Their Environmental Footprint (and Reduce Costs)?
Authors: Bajwa Barinder , Zhang Zach , Tuen Young Ji , Courtemanche Rebecca , S. Arneja Jugpal 
Published: January 2025

Introduction Every industry has greenhouse gas emissions, with healthcare a significant contributor. In Canada, the healthcare sector is directly and indirectly responsible for 4.6% of the country's greenhouse gas emissions. Operating rooms (ORs) are major contributors to hospital waste, making the OR low hanging fruit for analyzing environmental practices. The OR can adopt a green mindset to reduce its carbon footprint, yet barriers to going green exist. Herein we study non-hospital surgical centres in British Columbia to assess current green practices, attitudes towards environmental sustainability, and barriers to implementation. Methods All accredited non-hospital surgical centres in BC were invited to complete a survey on current practices and plans to reduce their environmental impact. Results Of 56 non-hospital surgical centres contacted, 18 responded, with 89% willing to adapt their practice to promote environmental sustainability, yet lacked current knowledge (56%) and formal plans (0%). The wide use of anesthetic gases with high global warming potential (64%) and disposable drapes/ gowns (78%/ 67%) were noted. Barriers to adopting green practices included: cost (44%), infrastructure (44%), regulatory guidelines (39%), knowledge (39%), and safety (28%). Conclusions Transitioning to more environmentally sustainable practices in ORs can enhance healthcare value by reducing both costs and greenhouse gas emissions. The greatest effect can be achieved through prudent choice of anesthetic gas agent, followed by reusable linens and drapes. Education and regulatory leadership were identified as crucial for overcoming these barriers. This study underscores the need for education, guidelines, and economically viable options to transition from awareness to action.
Optimizing time in harness
Authors: Bavan Luckshman , Bradley Catharine S. , Verma Yashvi , Kelley Simon P. 
Published: January 2025

AimsThe primary aims of this study were to determine the time to sonographic correction of decentred hips during treatment with Pavlik harness for developmental dysplasia of the hip (DDH) and investigate potential risk factors for a delayed response to treatment.MethodsThis was a retrospective cohort study of infants with decentred hips who underwent a comprehensive management protocol with Pavlik harness between 2012 and 2016. Ultrasound assessments were performed at standardized intervals and time to correction from centring of the femoral head was quantified. Hips with < 40% femoral head coverage (FHC) were considered decentred, and hips with > 50% FHC and α angles > 60° were considered corrected. Survival analyses using log-rank tests and Cox regression were performed to investigate potential risk factors for delayed time to correction.ResultsA total of 108 infants (158 hips) successfully completed the bracing protocol and were included in the study. Mean age at treatment initiation was 6.9 weeks (SD 3.8). All included hips centred within two weeks of treatment initiation. At two, five, eight, and 12 weeks following centring of the femoral head, 13% (95% CI 8 to 19), 67% (95% CI 60 to 74), 98% (95% CI 95 to 99), and 99% (95% CI 98 to 100) of hips had cumulatively achieved sonographic correction, respectively. Low α angles at presentation were found to be a risk factor for delayed time to correction (hazard ratio per 1° decrease in α angle 1.04 (95% CI 1.01 to 1.06); p = 0.006).ConclusionThe majority of decentred hips undergoing Pavlik treatment achieved sonographic correction within eight weeks of centring and radiological severity at presentation was a predictor for slower recovery. These findings provide valuable insights into hip development during Pavlik treatment and will inform the design of future prospective studies investigating the optimal time required in harness.Cite this article: Bone Joint J 2025;107-B(1):118–123.
Current concepts of fourth-generation minimally invasive and open hallux valgus surgery
Authors: Lewis Thomas L. , Barakat Ahmed , Mangwani Jitendra , Ramasamy Arul , Ray Robbie 
Published: January 2025

Hallux valgus (HV) presents as a common forefoot deformity that causes problems with pain, mobility, footwear, and quality of life. The most common open correction used in the UK is the Scarf and Akin osteotomy, which has good clinical and radiological outcomes and high levels of patient satisfaction when used to treat a varying degrees of deformity. However, there are concerns regarding recurrence rates and long-term outcomes. Minimally invasive or percutaneous surgery (MIS) has gained popularity, offering the potential for similar clinical and radiological outcomes with reduced postoperative pain and smaller scars. Despite this, MIS techniques vary widely, hindering comparison and standardization. This review evaluates the evidence for both open Scarf and Akin osteotomy and newer-generation MIS techniques. Fourth-generation MIS emphasizes multiplanar rotational deformity correction through stable fixation. While MIS techniques show promise, their evidence mainly comprises single-surgeon case series. Comparative studies between open and MIS techniques suggest similar clinical and radiological outcomes, although MIS may offer advantages in scar length and less early postoperative pain. MIS may afford superior correction in severe deformity and lower recurrence rates due to correcting the bony deformity rather than soft-tissue correction. Recurrence remains a challenge in HV surgery, necessitating long-term follow-up and standardized outcome measures for assessment. Any comparison between the techniques requires comparative studies. Surgeons must weigh the advantages and risks of both open and MIS approaches in collaboration with patients to determine the most suitable treatment.Cite this article: Bone Joint J 2025;107-B(1):10–18.
The risk of dislocation in dual-mobility versus 36 mm heads in primary total hip arthroplasty for osteoarthritis
Authors: Hussein Yousef , Iljazi Afrim , Sørensen Michala S. , Overgaard Søren , Petersen Michael M. 
Published: January 2025

AimsDislocation is a major concern following total hip arthroplasty (THA) for osteoarthritis (OA). Both dual-mobility components and standard acetabular components with large femoral heads are used to reduce the risk of dislocation. We investigated whether dual-mobility components are superior to standard components in reducing the two-year dislocation and revision risk in a propensity-matched sample from the Danish Hip Arthroplasty Register (DHR).MethodsThis population-based cohort study analyzed data from the DHR and the Danish National Patient Register. We included all patients undergoing primary THA for OA from January 2010 to December 2019 with either dual-mobility or standard acetabular components with metal-on-polyethylene or ceramic-on-polyethylene articulations with a 36 mm femoral head. The samples were propensity score-matched on patient and implant characteristics. The primary outcome was the difference in the absolute risk of dislocation within two years, with a secondary outcome of the difference in the absolute risk of revision surgery of any cause within the same timeframe. The cumulative incidence of dislocation was calculated using the Aalen-Johansen estimator, while the difference in absolute risk was estimated using absolute risk regression (ARR).ResultsWe included 4,499 patients with dual-mobility components and 4,499 patients with standard components after propensity score-matching. Both groups had a mean age of 75 years (SD 8.5), included approximately 60% females, and had a two-year survival of 95.3% (95% CI 94.6 to 95.9). The dual-mobility group was 80% less likely to dislocate within two years (ARR 0.20 (95% CI 0.14 to 0.28); p < 0.001), with no significant difference in the risk of revision compared to standard components (ARR 1.15 (95% CI 0.89 to 1.48); p = 0.293).ConclusionDual-mobility components are associated with a reduced risk of dislocation and with no significant difference in the risk of revision for any cause within two years of THA when compared to standard acetabular components with 36 mm femoral heads.Cite this article: Bone Joint J 2025;107-B(1):50–57.
Comparing cup placement, leg length, and offset discrepancy after total hip arthroplasty between CT-based robotic arm-assisted and navigation systems
Authors: Shimizu Akira , Murakami Satoshi , Tamai Takayuki , Haga Yuuki , Kutsuna Tatsuhiko , Kinoshita Tomofumi , Takao Masaki 
Published: January 2025

AimsExcellent outcomes have been reported following CT-based robotic arm-assisted total hip arthroplasty (rTHA) compared with manual THA; however, its superiority over CT-based navigation THA (nTHA) remains unclear. This study aimed to determine whether a CT-based robotic arm-assisted system helps surgeons perform accurate cup placement, minimizes leg length, and offsets discrepancies more than a CT-based navigation system.MethodsWe studied 60 hips from 54 patients who underwent rTHA between April 2021 and August 2023, and 45 hips from 44 patients who underwent nTHA between January 2020 and March 2021 with the same target cup orientation at the Department of Orthopedic Surgery at Ozu Memorial Hospital, Japan. After propensity score matching, each group had 37 hips. Postoperative acetabular component position and orientation were measured using the planning module of the CT-based navigation system. Postoperative leg length and offset discrepancies were evaluated using postoperative CT in patients who have unilateral hip osteoarthritis.ResultsThe absolute differences in radiological inclination (RI) and radiological anteversion (RA) from the target were significantly smaller in rTHA (RI 1.2° (SD 1.2°), RA 1.4° (SD 1.2°)) than in nTHA (RI 2.7° (SD 1.9°), RA 3.0° (SD 2.6°)) (p = 0.005 for RI, p = 0.002 for RA). The absolute distance of the target’s postoperative centre of rotation was significantly smaller in the mediolateral (ML) and superoinferior (SI) directions in rTHA (ML 1.1 mm (SD 0.8), SI 1.3 mm (SD 0.5)) than in nTHA (ML 1.9 mm (SD 0.9), SI 1.6 mm (SD 0.9)) (p = 0.002 for ML, p = 0.042 for SI). Absolute leg length and absolute discrepancies in the acetabular, femoral, and global offsets were significantly lower in the rTHA group than in the nTHA group (p = 0.042, p = 0.004, p = 0.003, and p = 0.010, respectively). In addition, the percentage of hips significantly differed with an absolute global offset discrepancy of ≤ 5 mm (p < 0.001).ConclusionrTHA is more accurate in cup orientation and position than nTHA, effectively reducing postoperative leg length and offset discrepancy.Cite this article: Bone Jt Open 2024;6(1):3–11.
240  Gbps SI-FMF/FSO communication system based on LP modes and PV code with the impact of foggy weather in Alexandria and Setif
Authors: Abd El-Mottaleb Somia A. , Bencheikh Abdelhalim , Singh Mehtab 
Published: January 2025

This paper presents a novel, to the best of our knowledge, high-speed
optical communication system
achieving a 240 Gbps transmission capacity by integrating
step-index few-mode fiber (SI-MMF) and free space optics (FSO).
Knowing that Hermite-Gaussian modes (HGMs) are eigenmodes of a free
space medium and the linearly polarized modes (LPMs) are eigenmodes of
step-index few-mode fiber (SI-FMF), and by considering the similarity
between HGM ( and ) and LPM ( and ), respectively, the system employs
dual-polarization (DP) and linearly polarized (LP) modes (, , and ), combined with optical code division
multiple access (OCDMA) using permutation vector (PV) codes. Each
polarization state carries data from three LP modes, with each mode
supporting four OCDMA channels, each assigned a unique PV code. The
system’s performance is evaluated under varying fog conditions using
key metrics such as quality-factor (Q-factor), bit error rate (BER),
and eye diagrams, which provide a comprehensive assessment of signal
strength and quality. Real-world applicability is assessed using
meteorological data from two African cities, Alexandria, Egypt, and
Setif, Algeria. System performance is characterized using the
Q-factor, bit error rate (BER), and eye diagrams. The results show
that, in Alexandria, successful transmission is achieved over
1.41 km. In Setif, the transmission distance is reduced to
1.31 km due to slightly higher atmospheric attenuation. These
ranges are observed at a BER below HG00 and a Q-factor exceeding 3.10.
Consequently, these findings confirm the viability of the proposed
system for high-capacity optical communication in challenging weather
conditions, making it suitable for future 6G networks.
Study on the performance of nanoparticle-modified PVDF membrane in delaying membrane aging
Authors: Lin Fuxing 
Published: January 2025

Abstract
With an emphasis on improving the membrane’s long-term durability and filtering efficiency, this study examines how well nanoparticle-modified polyvinylidene fluoride (PVDF) membranes perform in postponing membrane aging. The functionalization of PVDF membranes with mesoporous silica nanoparticles (MSNs) to increase their resistance to fouling and degradation makes this study novel. Sol–gel synthesis was used to create MSNs, which were then included in the PVDF membrane matrix. Brunauer–Emmett–Teller surface area analysis, X-ray diffraction, and scanning electron microscopy were used to analyze the structural characteristics of the modified membranes. The findings showed that adding MSNs improved the mechanical strength and permeability of the membrane by increasing its surface area and pore volume. Comparing the modified PVDF membranes to the unmodified membranes, aging tests revealed a slower drop in filtering performance and increased resilience to fouling and chemical degradation. According to these results, MSN-modified PVDF membranes are a promising material for water treatment and other filtering applications since they have a great deal of potential to increase the longevity and effectiveness of filtration systems.
Antimicrobial activity, induction of ROS generation in HepG2 liver cancer cells, and chemical composition of Pterospermum heterophyllum
Authors: Tu Quang Trung , Le Thi Thanh Huong , Nguyen Mai Quynh , Hoang Phu Hiep , Hoang Van Hung , Pham Van Khang , Nguyen Phu Hung 
Published: January 2025

Abstract
The objective of this investigation was to assess the inhibitory effects of extracts derived from Pterospermum heterophyllum on bacteria and fungi, as well as their capacity to impede the proliferation and migration of HepG2 liver cancer cells. Extracts from the leaves and stems of P. heterophyllum revealed the ability to resist all three bacterial strains, including Escherichia coli, Pseudomonas aeruginosa, and Streptococcus aureus (p < 0.05). Additionally, P. heterophyllum also inhibited the growth of three fungal strains: Aspergillus brasiliensis, Candida albicans, and Aspergillus flavus. Evaluation of anticancer activity showed that extracts from P. heterophyllum significantly reduced the proliferation of HepG2 cells, with IC50 values for leaf and stem extracts being 35.5 and 47.17 µg/mL, respectively. Remarkably, the extract of this herbal species inhibited the migration ability of HepG2 cells after 24 h of treatment. Fluorescence analysis of cells using 2-HDCFDA showed a considerable elevation in reactive oxygen species production within HepG2 cells treated with extracts, which is hypothesized to contribute to a reduction in cell viability. Subsequent chemical compound analysis utilizing GC-FID spectra identified some main compounds present in the extracts from P. heterophyllum. This study highlights the potential antimicrobial and anticancer activities of P. heterophyllum.