bluuebunny/crossref_metadata_2025_split huggingface dataset:
Desayuno y desempeño escolar en alumnos de tercero y sexto en primarias públicas en el municipio de Aguascalientes
Authors: Arriaga García P , Campos López A del S , Rodríguez- Ruiz M A 
Published: March 2021

El desempeño académico de los escolares ha sido asociado con muchos factores que condicionan su grado de aprendizaje. Es probable que muchos niños en nuestro país salgan de sus casas sin haber desayunado antes de ir a la escuela. El ayuno da lugar a una menos concentración de glucosa, elemento indispensable para el funcionamiento cerebral, con una consecuente disminución de la capacidad de las funciones congnitivas. En este trabajo se relacionó el desempeño académico en un grupo de escolares medido a través de sus calificaciones bimestrales, la primera basal y la segunda calificación después de haber recibido diariamente su desayuno.
Ars médica
Authors: Guevara Gloria , Cienfuegos Jesus , Hernández Collazo Adameck Abraham 
Published: March 2021

Espacio dedicado a escritores y artistas miembros, o no, de la comunidad médica, quienes podrán aportar textos y obras artísticas que contribuyan a mejorar la cultura en salud de la comunidad. Publicación financiada con recursos PIFI 2011
hidrola Enfermedad de células I de Leroy o mucolipidosis tipo II
Authors: Macri-Colucci Alberto , Barba-Calvillo Tania Alejandra 
Published: March 2021

La enfermedad de células I, de Leroy o mucolipidosis II, es un raro trastorno autosómico recesivo que produce un déficit en la enzima GlcNAc-fosfotransferasa alterando el transporte lisosomal y se caracteriza clínicamente por un peso bajo al nacer, malformaciones físicas, anomalías esqueléticas, organomegalias, severo retraso psicomotor y muerte entre los cinco y ocho años de edad debido a complicaciones cardiacas que se agrava con enfermedades pulmonares agregadas. Se presenta el reporte de un caso de un paciente masculino de tres años diez meses de edad, con manifestaciones clínicas compatibles con el diagnóstico de enfermedad de células I de Leroy, diagnóstico que se confirmó por medio de estudios bioquímicos específicos.
Uso de bloqueadores H2 como auxiliar en el diagnóstico del divertículo de Meckel
Authors: Alvarado-Murillo Ramón Fernando , Flores-Álvarez Efrén , Sánchez-Anaya Rosendo , Muñoz-Fernández Luis 
Published: March 2021

El divertículo de Meckel es una malformación congénita del intestino delgado. Cuando es sintomático se manifiesta con datos de oclusión, hemorragia, perforación o fístula. Aparte de la clínica, se utiliza como apoyo diagnóstico el centelleograma con tecnecio 99. La administración de bloqueadores H2 facilita el diagnóstico de divertículo de Meckel. La resolución de esta malformación congénita es quirúrgica. Se presenta el caso clínico de una paciente de 8 años en la que el diagnóstico se estableció posterior al tratamiento con bloqueadores de H2 y se resolvió mediante laparoscopía.
Estatinas
Authors: Prieto-Macías Jorge , Dávila-Ramírez Juan Antonio , Fierro-Rosales Víctor Andrés , Flores-Ávila Francisco Alberto , García-Diosdado Alfonso , Hernández-González Flavio , Martínez-Gutiérrez Jonathan Alejandro , Rivera-Sánchez Gilberto Raúl , Sandoval-Valdez Darío Alejandro 
Published: March 2021

Las estatinas surgieron como fármacos para disminuir los niveles plasmáticos del colesterol total. Su mecanismo de acción es la inhibición de la enzima hidroxi-3-metil-glutaril coenzima A reductasa (HMG-CoA reductasa). Esta enzima participa en la vía de síntesis del colesterol, pero además participa en la síntesis de otras moléculas como proteínas farnesiladas y proteínas geranilgeraniladas, entre otras. Debido a este mecanismo de acción, y quizás otros aún no completamente dilucidados, se han visto efectos pleiotrópicos de las estatinas en diversos tejidos y órganos, participando en patologías como la fibrosis pulmonar; fibrosis hepática, tromboembolismo sistémico, nefropatía por medio de contraste, fibrosis peritoneal en pacientes con diálisis peritoneal, cáncer, trasplante renal y enfermedad vascular cerebral (EVC), entre otros que se revisan en el artículo. También se han encontrado efectos adversos principalmente relacionados con hepatopatía y miopatía. LUX MÉDICA, AÑO 10, NÚMERO 29, ENERO-ABRIL 2015 PP 31-39
Prevalencia e índice de severidad de violencia de género en pareja en enfermeras de un hospital
Authors: Rodríguez-Medina Ma. de Lourdes , Rodríguez-Nava Víctor Federico , Rodríguez-Ramírez José Manuel , Gómez-Cardona Juan Pablo , Barba-Gallardo Luis Fernando 
Published: March 2021

Introducción: La violencia de género en pareja es un problema de salud pública, según la Encuesta de salud y derechos de las mujeres, es la manifestación más severa de desigualdad entre hombres y mujeres, situación que repercute en la integridad física, laboral y económica. Objetivo: Determinar la prevalencia e índice de severidad de violencia de género en pareja en enfermeras de un hospital. Material y métodos: Estudio observacional, descriptivo, transversal, en enfermeras de un hospital seleccionadas por muestreo aleatorio simple. Se aplicó el instrumento "Escala de violencia e Índice de severidad”, confiabilidad 0.99 por Cronbach, utilizando el programa SPSS V.22. Resultados: Participaron 190 enfermeras, edad 27 a 61 años, antigüedad laboral 17 años (D.E.±6), promedio de ingreso mensual $13.926 (±$3. 626M.N), tiempo de convivencia 15 años (±9), respecto a la violencia 67.9% nunca han recibido agresión por parte de la pareja. De las que la han recibido, 2.6% sufrieron los cuatro tipos de violencia. Por escala e índice de severidad, los casos severos se observaron en la violencia sexual con un 10.5%, seguida de la psicológica con 9.5%, física con 3.7%. Conclusiones: Tres de cada diez enfermeras con al menos un año de relación sufre violencia de género en pareja. El índice de severidad por tipo de violencia más frecuente es la sexual.LUXMÉDICA, AÑO 10, NÚMERO 30, MAYO-AGOSTO 2015, PP 3-13
Glomeruloesclerosis nodular idiopática: reporte de caso en paciente mexicana
Authors: Azúa Díaz Gerardo Gilberto , Reza Escalera Ana Lilián 
Published: March 2021

La glomeruloesclerosis nodular es un patrón histológico caracterizado por nódulos de material hialino de tamaño variable, encontrados en el mesangio renal. Dentro del diagnóstico diferencial, se encuentran la nefropatía diabética; disproteinemias como la amiloidosis y enfermedad por depósito de cadenas ligeras; glomerulopatías por depósito de material fibrilar como fibronectina, colágena III o inmunotactoide; condiciones hipóxicas, como la arteritis de Takayasu, microangiopatía trombótica crónica y la estenosis de la arteria renal; así como la glomerulonefritis membranoproliferativa. Se presenta el caso de una mujer joven no fumadora, normotensa, con normopeso, sin diabetes mellitus ni dislipidemia, la cual presenta en la biopsia renal glomeruloesclerosis nodular.
Compact Multi-Element Ultrasonic Transducer for Inspecting Split Pins in Nuclear Power Plants
Authors: Guanbing Ma , Hui Ding , Weiqiang Wang , Chao Ma , Jingli Yan , Chuanyu Zhu , Jianbang Tang 
Published: March 2021

A compact five-element integrated ultrasonic transducer was designed and manufactured for the inspection of defects in the split pins of control rod guide tubes in nuclear power plants. The transducer consists of three types of ultrasonic elements to detect cracks in the entire volume of the split pins. In the transducer design, two main factors were investigated: the coupling of elements in confined space and measurement sensitivity. The experimental results demonstrated that the developed transducer has good acoustic performance and defect response capabilities and can detect 10 mm × 2 mm × 0.5 mm notches in the three areas of the split pins. This work provides a foundation for applications in nuclear site inspections.
Exercise and Fitness Neuroprotective Effects: Molecular, Brain Volume and Psychological Correlates and Their Mediating Role in Healthy Late-Middle-Aged Women and Men
Authors: Castells-Sánchez Alba , Roig-Coll Francesca , Dacosta-Aguayo Rosalia , Lamonja-Vicente Noemí , Sawicka Angelika K. , Torán-Monserrat Pere , Pera Guillem , Montero-Alía Pilar , Heras-Tebar Antonio , Domènech Sira , Via Marc , Erickson Kirk I. , Mataró Maria 
Published: March 2021

Background: Although exercise is known to have a neuroprotective effect in aging, the mediators underlying the exercise-cognition association remain poorly understood. In this paper we aimed to study the molecular, brain, and behavioral changes related to physical activity and their potential role as mediators.Methods: We obtained demographic, physical activity outcomes [sportive physical activity and cardiorespiratory fitness (CRF)], plasma biomarkers (TNF-α, ICAM-1, HGF, SDF1-α, and BDNF), structural-MRI (brain volume areas), psychological and sleep health (mood, depressive and distress symptoms, and sleep quality), and multi-domain cognitive data from 115 adults aged 50–70 years. We conducted linear regression models and mediation analyses stratifying results by sex in a final sample of 104 individuals [65 women (age = 56.75 ± 4.96) and 39 men (age = 58.59 ± 5.86)].Results: Women engaging in greater amounts of exercising showed lower TNF-α levels and greater dorsolateral prefrontal cortex and temporal lobe volumes. Men engaging in greater amounts of exercise showed greater temporal lobe volumes. CRF levels were not related to any of the analyzed outcomes in women but in men higher CRF was associated with lower TNF-α, HGF and ventricle volumes, greater volume of temporal and parietal lobes and fewer depressive symptoms and better mood. In men, reduced TNF-α and HGF levels mediated brain and cognitive CRF-related benefits.Conclusion: Our results show that exercise is a promising approach for influencing inflammation and brain volume and also contributes to ongoing discussions about the physiological mediators for the association between CRF and cognition in men.
Longitudinal Evaluation of Serum MOG-IgG and AQP4-IgG Antibodies in NMOSD by a Semiquantitative Ratiometric Method
Authors: Bollo Luca , Iaffaldano Pietro , Ruggieri Maddalena , Palazzo Claudia , Mastrapasqua Mariangela , Manni Alessia , Paolicelli Damiano , Frigeri Antonio , Trojano Maria 
Published: March 2021

Background and purpose: Immunoadsorption (IA) is an antibody-depleting therapy used to treat neuromyelitis optica spectrum disorder (NMOSD) associated to antiaquaporin 4 (anti-AQP4-IgG) and antimyelin oligodendrocyte glycoprotein (anti-MOG-IgG) serum autoantibodies. Our aim was to evaluate longitudinal changes of serum MOG-IgG and AQP4-IgG antibody titer and to correlate it with the clinical status.Methods: Autoantibody titer and clinical features of two MOG-IgG+/AQP4-IgG– and two AQP4-IgG+/MOG-IgG– patients with NMOSD were collected at baseline (T0), after 6 IA courses (T1), and then 2 weeks (T2) and 6 months after treatment (T3). A fluorescent ratiometric assay was used for a quantitative detection of MOG and AQP4 antibodies, based on HEK-293 cells transfected with the full-length hMOG fused to GFP or h-AQP4-M23 isoform fused to m-cherry, respectively. We defined the antibody titer as MOG quantitative ratio (MOGqr) and AQP4 quantitative ratio (AQP4qr).Results: In Case 1, the MOGqr dropped from 0.98 at T0 to 0.14 at T3, and in Case 2, it decreased from 0.96 at T0 to undetectable at T3. In Case3, the AQP4qr remained high: 0.90 at T0 and 0.92 at T3. In Case 4, the AQP4qr decreased from 0.50 at T0 to undetectable at T3. Complete recovery was found in Cases 1, 2, and 4.Conclusions: Semiquantitative ratiometric method accurately detects even slight variation of MOG-IgG and AQP4-IgG titer, suggesting it may be useful to monitor the antibody titer during the disease course and maintenance immunotherapy.
An Observational Cohort Study and Nested Randomized Controlled Trial on Nutrition and Growth Outcomes in Moderate and Late Preterm Infants (FLAMINGO)
Authors: Kakaroukas Andreas , Abrahamse-Berkeveld Marieke , Berrington Janet E. , McNally Richard J. Q. , Stewart Christopher J. , Embleton Nicholas D. , van Elburg Ruurd M. 
Published: March 2021

Background: Over the past decades, the preterm birth rate has increased, mostly due to a rise in late and moderate preterm (LMPT, 32–36 weeks gestation) births. LMPT birth affects 6–7% of all births in the United Kingdom and is associated with increased morbidity risk after birth in infancy as well as in adulthood. Early life nutrition has a critical role in determining infant growth and development, but there are limited data specifically addressing LMPT infants, which was the rationale for the design of the current study.Objective: The Feeding Late and Moderate Infants and Growth Outcomes (FLAMINGO) study aims to improve understanding of the longitudinal growth, nutritional needs, and body composition of LMPT infants as well as their microbiome development and neurodevelopment. In addition, having a nested non-inferiority trial enables evaluation of the nutritional adequacy of a concept IMF with large milk phospholipid-coated lipid droplets comprising dairy and vegetable lipids. The primary outcome of this RCT is daily weight gain until 3 months corrected age.Methods: A total of 250 healthy LMPT infants (32+0–36+6 weeks gestational age) with birth weight 1.25–3.0 kg will be recruited to the cohort, of which 140 infants are anticipated to be enrolled in the RCT. During six visits over the first 2 years of life, anthropometry, body composition (using dual energy X-Ray absorptiometry), feeding behavior, and developmental outcomes will be measured. Saliva and stool samples will be collected for oral and gut microbiota assessment.Discussion: The FLAMINGO study will improve understanding of the longitudinal growth, body composition development, and feeding characteristics of LMPT infants and gain insights into their microbiome and neurodevelopment.Study Registration:www.isrctn.com; Identifier ISRCTN15469594.
The Impact of Microelectronics on High Energy Physics Innovation: The Role of 65 nm CMOS Technology on New Generation Particle Detectors
Authors: Demaria N. 
Published: March 2021

The High Luminosity Large Hadron Collider (HL-LHC) at CERN will constitute a new frontier for the particle physics after the year 2027. Experiments will undertake a major upgrade in order to stand this challenge: the use of innovative sensors and electronics will have a main role in this. This paper describes the recent developments in 65 nm CMOS technology for readout ASIC chips in future High Energy Physics (HEP) experiments. These allow unprecedented performance in terms of speed, noise, power consumption and granularity of the tracking detectors.
Hybrid Metamaterials Perfect Absorber and Sensitive Sensor in Optical Communication Band
Authors: Liu Xuehan , Li Keyang , Meng Zhao , Zhang Zhun , Wei Zhongchao 
Published: March 2021

A subwavelength metamaterial perfect absorber (MPA) in optical communication band was proposed and tested using the finite-difference time-domain method. The absorber is periodic and comprises a top layer of diamond silicon surrounded by L-shaped silicon and a gold layer on the substrate. It can achieve dual-band perfect absorption, and one of the peaks is in the optical communication band. By changing the gap (g) between two adjacent pieces of L-shaped silicon, and the thickness (h) of the silicon layer, the resonance wavelength of absorption peak can be tuned. When the incident electromagnetic wave entered the absorber, the metamaterial absorber could almost completely consume the incident electromagnetic waves, thereby achieving more than 99% perfect absorption. The absorption peak reaches 99.986% at 1310 nm and 99.421% at 1550 nm. Moreover, the MPA exposed to different ambient refraction indexes can be applied as plasma sensors, and can achieve multi-channel absorption with high figure of merit (FOM*) value and refractive index (RI) sensitivity. The FOM* values at 1310 nm and 1550 nm are 6615 and 168, respectively, and both resonance peaks have highly RI sensitivity. The results confirm that the MPA is a dual-band, polarization-independent, wide-angle absorber and insensitive to incident angle. Thence it can be applied in the fields of optical communication, used as a light-wave filter and plasma sensor, and so on.
Do Probiotics During In-Hospital Antibiotic Treatment Prevent Colonization of Gut Microbiota With Multi-Drug-Resistant Bacteria? A Randomized Placebo-Controlled Trial Comparing Saccharomyces to a Mixture of Lactobacillus, Bifidobacterium, and Saccharomyces
Authors: Wieërs Grégoire , Verbelen Valérie , Van Den Driessche Mieke , Melnik Ekaterina , Vanheule Greet , Marot Jean-Christophe , Cani Patrice D. 
Published: March 2021

Objective: Most infections with Enterobacteriaceae producing AmpC β-lactamase (AmpC)-, extended-spectrum β-lactamase (ESBL)-, and carbapenemase-producing bacteria, vancomycin-resistant Enterococcus as well as naturally resistant non-fermenting bacteria such as Pseudomonas aeruginosa, are related to a prior colonization of the gut microbiota. The objective of this study was to determine whether treatment with probiotics during an antibiotic treatment could prevent the colonization of the gut microbiota with multi-drug resistant bacteria.Method: In total, 120 patients treated for 10 days with amoxicillin-clavulanate antibiotics were included in a randomized, placebo-controlled, double-blinded trial, comparing the effects of a 30 days treatment with placebo Saccharomyces boulardii CNCM I-745® and a probiotic mixture containing Saccharomyces boulardii, Lactobacillus acidophilus NCFM, Lactobacillus paracasei Lpc-37, Bifidobacterium lactis Bl-04, and Bifidobacterium lactis Bi-07 (Bactiol duo®). Study treatment was initiated within 48 h of the antibiotic being initiated. Most of the patients included were elderly with a mean age of 78 years old with multiple comorbidities. Stools were collected at the time of inclusion in the trial, at the end of the antibiotic treatment, and the end of the study treatment. These were cultured on selective antibiotic media.Results: Treatment with the probiotic mixture led to a significant decline in colonization with Pseudomonas after antibiotic treatment from 25 to 8.3% (p = 0.041). Colonization with AmpC-producing enterobacteria was transiently increased after the antibiotic treatment (p = 0.027) and declined after the probiotic intervention (p= 0.041). No significant changes were observed in the placebo and Saccharomyces groups. Up to 2 years after the trial, no infection with ESBL-producing bacteria was observed in the probiotic mixture group.Conclusion: The association of Saccharomyces boulardii with specific strains of Lactobacillus and Bifidobacterium influences antibiotic treatment by counteracting the colonization of the colon microbiota with antibiotic-resistant pathogens.
Early and Long-Term Outcomes of Carotid Stenting and Carotid Endarterectomy in Women
Authors: Pasqui Edoardo , de Donato Gianmarco , Alba Giuseppe , Brancaccio Brenda , Panzano Claudia , Cappelli Alessandro , Setacci Carlo , Palasciano Giancarlo 
Published: March 2021

Background: The role of carotid revascularization in women remains intensely debated because of the lower benefit and higher perioperative risks concerning the male counterpart. Carotid artery endarterectomy (CEA) and stenting (CAS) represent the two most valuable stroke prevention techniques due to large vessel disease. This study investigates the early and late outcomes in female sex in a real-world everyday clinical practice.Methods: Data were retrospectively analyzed from a single-center database prospectively compiled. A total of 234 procedures, both symptomatic and asymptomatic, were identified (98 CEAs and 136 CASs). Perioperative risks of death, cerebral ischemic events, and local complications were analyzed and compared between the two groups. Long-term outcomes were evaluated in overall survival, freedom from ipsilateral stroke/transient ischemic attack, and freedom from restenosis (&gt;50%) and reintervention.Results: Women who underwent CAS and CEA did not differ in perioperative ischemic cerebral events (2.2 vs. 0%, p = 0.26) and death (0.8 vs. 0%, p = 1). Other perioperative and 30-day outcomes were similarly distributed within the two groups. Kaplan–Meier curves between CAS and CEA groups highlighted no statistical differences at 6 years in overall survival (77.4 vs. 77.1%, p = 0.47) of ipsilateral stroke/transient ischemic attack (94.1 vs. 92.9%, p = 0.9). Conversely, significant differences were showed in 6 years freedom from restenosis (93.1 vs. 83.3%, p = 0.03) and reinterventions (97.7 vs. 87.8%, p = 0.015).Conclusion: Our results revealed that both CEA and CAS have acceptable perioperative risk in women. Long-term outcomes highlighted favorable indications for both procedures, especially for CAS, which seemed to be an excellent alternative to CEA in female patients when performed by well-trained operators.
Mobilização Precoce Pós Acidente Vascular Cerebral: Revisão Integrativa
Authors: Motta dos Anjos Jorge Luis , Costa Oliveira Laíse , Rodrigues Ribeiro Lopes Lilian , Rodrigues Durães André 
Published: March 2021

Introdução. Um programa de reabilitação precoce após AVC, onde são utilizadas estratégias e intervenções com a finalidade de favorecer a capacidade de realizar tarefas é de fundamental importância para acelerar a recuperação, além de prevenir complicações secundárias e reduzir os custos da hospitalização. Objetivo. Revisar as publicações sobre mobilização precoce e seus efeitos quando aplicada em pacientes com diagnóstico de Acidente Vascular Cerebral na fase aguda da doença. Método. Trata-se de uma revisão integrativa da literatura, através das bases de dados eletrônicas Scientific Electronic Library Online (SciELO) e literatura internacional em Ciências da Saúde (MEDLINE). O período de abrangência foi entre janeiro de 2015 a janeiro de 2020. Resultados. Dentre os estudos incluídos nesta revisão, 01 realizou estudo de grupo único, comparando achados antes e após a mobilização precoce, 01 foi uma revisão da literatura, 01 foi uma revisão sistemática da literatura, 01 estudo de coorte com pacientes com diagnóstico de AVC isquêmico submetidos a Trombólise, 07 foram ensaios clínicos. Conclusões. A mobilização precoce pode aperfeiçoar acelerar a recuperação, além de ajudar a prevenir complicações secundárias, reduzir os custos da hospitalização, sendo também segura e eficaz, porém quando comparada aos cuidados usuais, não demonstrou superioridade.
PENGATURAN PENDIDIKAN PROFESI ADVOKAT DI INDONESIA
Authors: Mustakim Mustakim 
Published: March 2021

The implementation of Professional Advocate Certification is deemed to be incompatible with the standards in organizing professional education as regulated by Law no. 20 of 2003 on the National Education System and Law no. 12 of 2012 on Higher Education, causing uncertainty and unscrupulous on the quality of prospective advocates, detrimental to the legal environment in whole. The Profession of Advocates possesses a strategic position in law enforcement to uphold justice, therefore this occupation is known to be a noble profession (offi cium nobile). The problem formulation in this research is to set the framework of implementing Professional Advocate Certifi cation to maintain the professionalism and integrity of advocates and to organize the implementation of Professional Advocate Certifi cation in the coming days. With the use of normative approach as the method of research by utilizing statutory regulations, court decisions, and legal concepts, this study found that Professional Advocate Certifi cation must be carried out in collaboration with universities in accordance with the mandate of the Constitutional Court Decision (MKRI) No. 95/PUU-XIV/2016 date 23rd of May 2017, Decision Number 46 P/HUM/2019, Thursday, 26th of September 2019 and Decision Number 87 P/HUM/2019 on the date 13th of December 2019 and Regulation of the Minister of Research, Technology, and Higher Education Number 5 of 2019. Therefore, it is crucial to accomplish fundamental changes concerning the implementation of advocate professional education by constructing curriculum changes leading up to the integrity and expertise in maintaining the noble reputation of the advocates’ role (officium nobile).