bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Kinematic Perspective on the Formation Process of the Stellar Groups in the Rosette Nebula
Authors: Lim Beomdu , Nazé Yaël , Hong Jongsuk , Park Byeong-Gon , Yun Hyeong-Sik , Yi Hee-Weon , Park Sunkyung , Hwang Narae , Lee Jeong-Eun 
Published: July 2021

Abstract
Stellar kinematics is a powerful tool for understanding the formation process of stellar associations. Here, we present a kinematic study of the young stellar population in the Rosette nebula using recent Gaia data and high-resolution spectra. We first isolate member candidates using the published mid-infrared photometric data and the list of X-ray sources. A total of 403 stars with similar parallaxes and proper motions are finally selected as members. The spatial distribution of the members shows that this star-forming region is highly substructured. The young open cluster NGC 2244 in the center of the nebula has a pattern of radial expansion and rotation. We discuss its implication on the cluster formation, e.g., monolithic cold collapse or hierarchical assembly. On the other hand, we also investigate three groups located around the border of the H ii bubble. The western group seems to be spatially correlated with the adjacent gas structure, but their kinematics is not associated with that of the gas. The southern group does not show any systematic motion relative to NGC 2244. These two groups might be spontaneously formed in filaments of a turbulent cloud. The eastern group is spatially and kinematically associated with the gas pillar receding away from NGC 2244. This group might be formed by feedback from massive stars in NGC 2244. Our results suggest that the stellar population in the Rosette Nebula may form through three different processes: the expansion of stellar clusters, hierarchical star formation in turbulent clouds, and feedback-driven star formation.
Un stigmate de la parole
Authors: Bourguignon Abigail 
Published: July 2021

Explorant l’inscription corporelle du bégaiement, entendu comme stigmate de la parole, l’article montre comment la parole et le corps, en tant que terrains de classements sociaux, participent ensemble à la définition des normes du « bien parler ». À partir d’une enquête ethnographique menée sur trois terrains (Île-de-France, Hauts-de-France, La Réunion), il revient sur la manière dont les bègues décèlent dans les yeux de leurs interlocuteurs et sur leur propre corps les signes de leur « anormalité ». Les regards qui se posent sur les corps des bègues contribuent à produire cette déviance langagière, chez les bègues eux-mêmes, avec leurs interlocuteurs, comme dans leurs relations avec les orthophonistes. L’analyse s’attache d’une part à considérer le rôle de ces lectures des corps et manières de se tenir dans le travail de la parole qui prend place dans les cabinets d’orthophonie, d’autre part à envisager ces lectures comme le fruit de processus de socialisation marqués par d’importantes inégalités sociales et genrées entre les bègues.
L’éclairage sur la sollicitude selon Paul Ricœur pour repenser le soin
Authors: Furstenberg Cécile 
Published: July 2021

La sollicitude est un terme usité dans le langage courant, proche du soin, du souci. Paul Ricœur lui a donné une place singulière dans sa « petite éthique » et en a révélé son épaisseur. La sollicitude selon Paul Ricœur s’apparente au care et pourtant n’en est pas sa traduction. Préciser la spécificité de la sollicitude de Paul Ricœur permet de mieux en percevoir les enjeux pour repenser le soin. Voici l’éclairage sur la sollicitude selon Paul Ricœur pour repenser le soin.
Le sommeil partagé : parental proximal pour l’enfant dans ses 1 000 premiers jours
Authors: Riquet Sébastien , Roussel Manon , Vigie Marine , Zakarian Carole , Hassler Pascale 
Published: July 2021

Introduction : dormir avec son nourrisson relève d’une pratique parentale proximale ; dans certaines sociétés, 80 % des enfants dorment avec leurs parents. En France, la culture séparée du sommeil s’est imposée, et la pratique du sommeil partagé est associée à la mort inattendue du nourrisson (MIN). Des recommandations internationales encadrent cette pratique peu recommandée et dévalorisée. Matériel et méthodes : deux focus groupes avec des codormeuses (n=6) complétés par dix entretiens en profondeur ont été organisés pour identifier les motivations et l’organisation des mères et de leur couple à pratiquer le sommeil partagé avec leurs enfants. L’analyse de contenus, communs aux dits personnels, a permis de décrypter des besoins auxquels le sommeil partagé répond et les pratiques des parents. Résultats : la mort inattendue du nourrisson rend tabou le sommeil partagé qui répond à des facteurs émotionnels et pratiques. La vie de couple ne semble pas y être impactée négativement. La relation positive des parents à leurs enfants y est valorisée. L’organisation peut parfois sembler manquer de « sécurité » selon les recommandations, mais les codormeurs soutiennent cette pratique parentale de pair avec l’allaitement maternel. Conclusion : les résultats relèvent l’importance d’une éducation à la santé à l’attention des codormeurs pour sécuriser leur pratique afin qu’ils ne s’isolent pas socialement pour la dissimuler car ils ont une connaissance partielle des mesures de sécurité de la MIN.
Étude exploratoire de la perception des parties prenantes hospitalières vis-à-vis de l’implantation des infirmiers en pratique avancée
Authors: Schwingrouber Jocelyn , Loschi Alain , Gentile Stéphanie , Colson Sébastien 
Published: July 2021

Introduction : une solution proposée par les autorités pour faire face aux enjeux de santé publique consiste à déployer une nouvelle catégorie de professionnels à compétences élargies : les infirmiers en pratique avancée (IPA). La littérature identifie la complexité des projets de déploiement de ces professionnels. Le modèle PEPPA, approuvé par le conseil international des infirmiers, représente le modèle de référence pour l’implantation des IPA. Les objectifs de cette étude étaient d’explorer la perception des parties prenantes vis-à-vis de l’implantation des IPA en établissement de santé afin de proposer des recommandations pour accompagner les établissements. Méthode : une étude qualitative multicentrique au sein de la région PACA a été menée auprès de médecins, encadrants, infirmiers, patients et étudiants en pratique avancée. Résultats : les IPA représentent une opportunité pour les patients et le système de santé, mais leur implantation comporte des risques liés à leur intégration. Les projets d’implantation IPA doivent être anticipés et favoriser leur intégration. Discussion : les résultats en adéquation avec le modèle PEPPA ont permis de proposer sept recommandations pour faciliter une implantation de qualité à l’hôpital. Conclusion : ce travail nécessite d’être poursuivi avec des études en lien avec l’extrahospitalier et l’évaluation de la qualité de l’implantation.
Development of a semiochemical-based trapping technique for efficient control ofOdoiporus longicollisOlivier (Coleoptera: Curculionidae)
Authors: Palanichamy S. , Boopathi T. , Uma S. 
Published: July 2021

AbstractThe banana stem weevil,Odoiporus longicollisOlivier (Coleoptera: Curculionidae), is an important economic insect pest of bananas throughout the world. In this study, several important volatile substances were analysed to develop a semiochemical-based trapping technique for the control ofO. longicollis. Electroantennogram responses of both sexes were associated with electroantennogram-active compounds (1-hexanol, 1-heptanol,cis-3-Nonen-1-ol, methyl jasmonate, and terpenoids such as (–)-linalool, (+)-(1R)-α-pinene, (–)-(1S)-α-pinene, and 1,8-cineole) and then were analysed using a Y-tube olfactometer. The results revealed that only methyl jasmonate and 1-hexanol elicited strong behavioural responses inO. longicollis. These two semiochemicals and the host plant extract were evaluated individually and in a mixture for their efficiencies in attractingO. longicollisin order to develop a semiochemical-based trapping technique. The methyl jasmonate + host plant extract and 1-hexanol + host plant extract mixtures captured more weevils (> 3.5 times) than the host plant extract alone did in both high- and low-altitude regions. The captured weevils were female-dominated, with a mean sex ratio of 1:1.29 (males:females). This is the first report on the use of methyl jasmonate or 1-hexanol and the host plant extract as a potential attractant in mass trapping and managingO. longicollis.
SIGIRR Negatively Regulates IL-36–Driven Psoriasiform Inflammation and Neutrophil Infiltration in the Skin
Authors: Giannoudaki Eirini , Stefanska Anna M , Lawler Hazel , Leon Gemma , Hernandez Santana Yasmina E , Hassan Najma , Russell Shane E , Horan Rachel , Sweeney Cheryl , Preston Roger S , Mantovani Alberto , Garlanda Cecilia , Fallon Padraic G , Walsh Patrick T 
Published: July 2021

Abstract
SIGIRR has been described as a negative regulator of several IL-1R/TLR family members and has been implicated in several inflammatory disease conditions. However, it is unknown whether it can suppress IL-36 family cytokines, which are members of the broader IL-1 superfamily that have emerged as critical orchestrators of psoriatic inflammation in both humans and mice. In this study, we demonstrate that SIGIRR is downregulated in psoriatic lesions in humans and mice, and this correlates with increased expression of IL-36 family cytokines. Using Sigirr−/− mice, we identify, for the first time (to our knowledge), SIGIRR as a negative regulator of IL-36 responses in the skin. Mechanistically, we identify dendritic cells and keratinocytes as the primary cell subsets in which IL-36 proinflammatory responses are regulated by SIGIRR. Both cell types displayed elevated IL-36 responsiveness in absence of SIGIRR activity, characterized by enhanced expression of neutrophil chemoattractants, leading to increased neutrophil infiltration to the inflamed skin. Blockade of IL-36R signaling ameliorated exacerbated psoriasiform inflammation in Sigirr−/− mice and inhibited neutrophil infiltration. These data identify SIGIRR activity as an important regulatory node in suppressing IL-36–dependent psoriatic inflammation in humans and mice.
Effect of short- and long-term immunization of recombinant disorganized muscle protein-1 (rDIM-1) against human filarial parasite Brugia malayi in rodents
Authors: Kushwaha Vikas , Murthy Puvvada Kalpana 
Published: July 2021

Objective:
To evaluate the effect of short-term and long-term immunization of recombinant disorganized muscle protein-1 (rDIM-1) in rodents against human filarial parasite Brugia malayi.

Methods:
Recombinant Brugia malayi DIM-1 (rDIM-1bm) protein was cloned, expressed and purified using a Ni-NTA affinity column. Mastomys coucha were immunized with rDIM-1bm in three immunization schedules: short-term (3-dose of rDIM-1bm), and long-term (booster doses till 3- and 6-week) and subsequently challenged with infective third-stage larvae of filarial parasite Brugia malayi (L3). Microfilaraemia was monitored in L3 exposed groups on day 90 post larval inoculation (p.l.i.) and continued till day 205 p.l.i. On day 205 p.l.i. all the infected animals were killed and total worm burden was estimated. Cellular proliferative response, macrophage activity, nitric oxide (NO) release, specific IgG and its subtypes, IgE, IgA and Th1 (IFN-γ, TNF-α and IL-2) and Th2 (IL-4, IL-5, IL-6, IL-10 and IL-13) cytokine release were determined.

Results:
Of the 3 different immunization schedules, short-term immunization (3-dose schedule) showed better reduction in microfilarial burden (36%-63%) in the peripheral circulation, adult worm load (52%), whereas long-term immunization (3- and 6-week schedule) exerted less effect on peripheral microfilariae count (9%-58%), and adult worm burden (9%-12.5%). Short-term immunization resulted in upregulation of cellular proliferation, macrophages activity, NO release, specific IgG, IgG1, IgG2a, IgG2b, IgE and IgA levels and both Th1 (IFN-γ, TNF-α and IL-2) and Th2 (IL-4, IL-5, IL-6, IL-10 and IL-13) cytokine release whereas long-term immunization (3- and 6-week schedule) exerted less effect on parasite burden and showed mixed immunological responses. None of the rDIM-1bm administration schedules induced any pathology in lymphoid tissues, or alteration in mast cell number and granularity.

Conclusions:
The short-term immunization with rDIM-1bm (3-dose schedule) induces robust immune responses and protects the host from filarial parasite infection.
Antibacterial resistance patterns of Acinetobacter baumannii complex
Authors: Mostafavi Sayed Nassereddin , Rostami Soodabeh , Nokhodian Zary , Ataei Behrooz , Cheraghi Azam , Ataabadi Parisa , Almasi Naser , Norouzi Zohreh , Kelishadi Roya 
Published: July 2021

Objective:
To determine the antibiotic resistance patterns of the Acinetobacter (A.) baumannii complex isolates that cause the confirmed infection.

Methods:
The present descriptive study was performed from March 2016 to March 2018 in three referral hospitals in Isfahan, Iran. All A. baumannii complex strains isolated from different clinical samples were identified by conventional phenotypic methods and antibiotic susceptibility pattern was detected. After the clinical investigation, contaminated samples were excluded and the source (hospital/community) and site of the infection were determined. Data on antibiotic susceptibility testing were extracted from WHONET software and analysis was done with SPSS.

Results:
From 254 patients who had confirmed A. baumannii complex infection, 158 (62.20%) cases were male, 27 (10.63%) were less than 20 years old, 172 (67.72%) had healthcare-associated infections and 96 (37.79%) were admitted in intensive care units. The most frequent infection was bloodstream infections (111, 43.70%). Our results showed that most of the isolates were resistant to most of the antibiotics (more than 75.00%) and a lower rate of non-susceptibility was observed against minocycline (20, 44.44%) and colistin (0%). The rate of multidrug-resistant isolates was 88.97%. There was no significant difference between resistance of A. baumannii complex isolates according to age. However, the resistance to amikacin and minocycline and the rate of multidrug resistance (MDR) were significantly different between males and females. In patients with healthcare associated infection (HAI), MDR isolates were significantly different regarding admission in ICU ward. Resistance to levofloxacin and ciprofloxacin were lower in isolates from patients with bloodstream infections in comparison to other diagnoses.

Conclusions:
In our study, a high level of antibiotic resistance was detected in both community-acquired and healthcare-associated A. baumannii complex infections. Appropriate antibiotic prescription in a clinical setting is an essential need for the control and prevention of A. baumannii resistant infections.
Phylogeny of Brucella abortus strains isolated in the Russian Federation
Authors: Kovalev Dmitry A. , Ponomarenko Dmitriy G. , Pisarenko Sergey V. , Shapakov Nikolay A. , Khachaturova Anna A. , Serdyuk Natalia S. , Bobrysheva Olga V. , Kulichenko Alexander N. 
Published: July 2021

Objective:
To study Brucella (B.) abortus strains isolated in the Russian Federation, in order to identify their detailed position in the phylogenetic structure of the species global population as well as to determine genetic relationships for isolates from different geographical areas.

Methods:
Based on Bayesian method, the whole genome single-nucleotide polymorphism (SNP) analysis of 258 B. abortus strains from different geographical areas of the world including 20 B. abortus strains isolated in Russia was carried out.

Results:
The core genome SNP analysis of the B. abortus isolates allowed describing the main genetic lineages. The Russian strains entered two separate clades, including the basal branch and the C1 branch that is widely spread in Eurasia. The data on the isolation time was used for the dating of phylogenetic tree, and also the estimated time frame for the B. abortus genotype diversification was determined. There were sets of specific SNPs identified, which defined each of the genotypes and sub-genotypes.

Conclusions:
A significant genetic diversity of the brucellosis pathogen strains from Russia has been proven. The sets of unique specific SNPs described in our study may become one of the elements within a bio-informational analysis algorithm to be used for epidemiological study of brucellosis outbreaks, including those caused by new (atypical) genetic variants of B. abortus.
Growth and Development Assessment of Children (1–5 Years) Operated for Tracheoesophageal Fistula/Esophageal Atresia
Authors: Maan Monika , Kaur Sukhwinder , Kalyan Geetanjli , Samujh Ram , Peters Nitin James , Bharti Bhavneet , Malhi Prahbhjot 
Published: July 2021

Introduction:
Among children, esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) is one of the major and common congenital anomalies. It is a life-threatening emergency and at birth may be associated with three C's coughing, choking, and cyanosis. It requires surgical interventions in the early neonatal period. The postsurgical period is associated with poor growth which can be developmental outcomes particularly in the first 5 years of life and attributed to postsurgical complications. The aim of the study is to assess and compare the growth and development of the children (1–5 years) operated for TEF/EA attending Pediatric Surgery OPD/admitted inwards at APC, PGIMER, Chandigarh versus healthy controls.

Materials and Methods:
A case–control study was conducted on age-matched 40 children aged between 1 and 5 years operated for TEF/EA and healthy controls. The sampling technique for cases was total enumeration and for controls was purposive sampling. Tools used were socio-demographic sheets of children, clinical profile of children, Trivandrum Development Screening chart, and Vineland Social Maturity Scale for Indian adaptation.

Results:
Majority 33 (82.5%) of children had distal TEF and more than two-third 28 (70%) have undergone primary repair. More than one-third 14 (35%) had a respiratory infection, 12 (30%) anastomosis leakage and 6 (15%) had Gastroesophageal reflux (GER) as one of the early and late postoperative complications. More than one-fourth 11 (27.5%) of TEF/EA operated children had less weight, 11 (30%) had less height and 16 (40%) had less weight for height for their reference age. A significant difference was found for height for age, weight for height, and social maturity among children who had TEF repair as compared to their healthy counterparts.

Conclusion:
Growth monitoring reflected (more than one-fourth of children were underweight and stunted while more than one-third were wasted) and showed development delay in TEF/EA operated children as compared to healthy controls.
Basic Oral Health Knowledge and Awareness among Rural Adults
Authors: Bhangu Amanpreet Kaur , Dhillon Mehraab , Ghuman Karan Singh , Kumar Mandeep , Goel Richa , Gambhir Ramandeep Singh 
Published: July 2021

Background:
It is very important to identify common oral health problems particularly in rural areas and create awareness for the same so that people can make informed choices. This study was conducted among the adult population residing in rural areas to assess their oral health knowledge and awareness.

Materials and Methods:
A descriptive cross-sectional study was conducted among adult population residing in rural areas around the dental clinic. A total of 662 participants constituted the final sample size after making necessary exclusions. A self-designed close-ended questionnaire written in English and Punjabi (local language) was constructed specifically for the study. The questionnaire was split into two sections. Analysis of variance and t-test were used in statistical analysis.

Results:
Majority of the participants (450, 68%) were male and 42.6% (282) of participants were in the age group of 41–50 years. Only 38% (251) of participants gave a positive response when asked about the importance of good oral health. About 40.2% (264) of participants believed that dental problems get cured solely by medicines. Low knowledge scores were recorded in 38.2% (252) of participants. Mean knowledge scores of the study participants were significantly associated with education (0.016) and occupation (0.027).

Conclusion:
Oral health knowledge and awareness among majority of study participants were not satisfactory. Therefore, the study emphasizes an urgent need for dental awareness and education programs targeting the rural masses.
Relation between Media Habits with Behavior Management Problems Along with Dental Anxiety during Dental Procedures in Children
Authors: Deolia Shravani , Chaurasia Abhishree Vinod , Kohale Renuka Ajay , Makode Sonal Shrikrushna , Nimbulkar Gargi , Chhabra Kumar Gaurav 
Published: July 2021

Background:
Relationship between children's media habit with their anxiety and behavior management problems (BMPs) is clinically relevant in establishing the link of usage of social media with dental fear and problems in behavior management during dental chairside treatment. Hence, the aim of the present study was to investigate the relation between media habits with BMPs along with dental anxiety (DA) during dental procedures in children.

Materials and Methods:
Overall, fifty patients of 3–10 years old were selected. DA and BMP were recorded by application of Clinical Anxiety Rating Scale and Frankel's Rating Scale in dental procedure. Parents reported their own DA on a Likert scale and also the time spend on using media and its type by children as well as parents was noted. Analysis of data was done with Mann–Whitney U and Chi-square test at “P < 0.05” significant level.

Results:
In children with BMP, TV watching and overall usage of electronic media were found more compared to those without BMP, this was significant. There was no significant correlation of total hours of TV watching and overall media time in children with DA. While in children with BMP, TV watching and overall usage of electronic media were found more compared to those without BMP, this was significant. There was a significant correlation of total hours of TV watching and overall media time in children with DA and BMP.

Conclusions:
There was a significant relation between BMPs with media usage in children while the same was insignificant with DA.