bluuebunny/crossref_metadata_2025_split huggingface dataset:
Medical errors in providing emergency care to patients with ECG symptoms of acute coronary syndrome on the background of decompensation of diabetes mellitus with hyperkalemia
Authors: Toronchenko O. M. , Miakinkova L. О. , Baklytskyi D. D. 
Published: October 2021

The article describes a rare clinical case of hyperkalemia backgrounded by type 1 diabetes mellitus with signs of acute cardiovascular insufficiency, arrhythmia and QRST disturbances which was primarily diagnosed as acute coronary syndrome with ST elevation. Coronary angiography excluded pathology of the coronary arteries. Hyperkalemia, as the cause of ECG changes, was suspected in the hospital treatment. Stabilization of the patient’s condition, renewal of heart rhythm and conduction was obtained against the background of infusion support and insulin therapy. The pathogenesis of arrhythmia and QRST complex had a secondary genesis in relation to fluid and electrolyte metabolism disorders, so the restoration of sinus rhythm occurred without usage of antiarrhythmics. The usage of antiarrhythmic drugs according to the guideline of management of patients with ACS can deepen electrolyte shifts and lead to fatal arrhythmias in conditions of insulin deficiency and hyperkalemia.
This example illustrates the urgent need to diagnose life-threatening electrolyte changes, namely hyperkalemia, under the guise of acute coronary syndrome, as well as signs of ACS, along with ECG, to pay special attention to the assessment of medical history and clinical data for the correct choice of emergency care and further treatment tactics.
Relationships between morphological indicators of the tibia and soft tissues lesions and some biochemical blood indicators in patients with traumatic osteomyelitis
Authors: Hryhorovskyi V. V. , Mahomedov S. , Hrytsai M. P. , Tsokalo V. P. , Kuzub T. A. , Polishchuk L. V. , Hryhorovska A. V. 
Published: October 2021

Aim. Research aim was to find statistical differences of biochemical indicators of blood and morphometric indicators of crural tissue lesion and relationships between them in patients with traumatic osteomyelitis of the tibia with trophic disturbances in extremity.
Material and methods. The work material includes data from 28 patients with traumatic osteomyelitis which was combined with trophic tissue disturbances of different manifestation degree. The levels of procalcitonin, lactate dehydrogenase and acetylcholinesterase of blood serum were estimated. In crural tissues quantitative biochemical, gradual morphometric indicators, frequencies of occurrence of different manifestation degree cases and relationships “clinic – biochemistry – pathomorphology” were defined histologically.
Results. Average values of procalcitonin, lactate dehydrogenase and acetylcholinesterase in patients with traumatic osteomyelitis of the tibia, combined with trophic disturbances in crural tissues, are significantly higher, than average values of these indicators in intact donors. In the majority of the patients with chronic traumatic osteomyelitis in crural tissues pathological changes were found out, which by clinical estimations are considered as trophic disturbances. They represent a combination of discirculatory, ischemic-necro­tic, exsudative, productive-inflammatory, and also reparative processes which in total create a composite picture of complex lesion and can persist for many years. As closest relations, according to values of association coefficient, concerning certain biochemical indicators, can be noted such clinical indicators: “degree of bone fragments non-consolidation” and “severity of trophic disturbances in bone tissue (by clinical estimation)”, concerning defined morphometric indicators – such biochemical indicators: “level of procalcitonin” and “level of lactate dehydrogenase” in blood serum. Among morphometric lesion indicators the closest relations concerning biochemical indicators were revealed: in bones – “the form of the pathological focus of traumatic osteomyelitis” and “presence of sequesters”, in soft tissues – “exsudative inflammation in internal membrane of a focus capsule”.
Conclusions. In chronic traumatic osteomyelitis combined with trophic disturbances of crural tissues, there are relationships between some clinical, biochemical and morphological indicators of the extremity tissues condition. A deviation of metabolism indicators from norm can serve as biochemical markers in definition of severity degree and efficiency of treatment in patients.
Financial Innovation and Technology after COVID-19: a few Directions for Policy Makers and Regulators in the View of Old and New Disruptors
Authors: Pompella Maurizio , Costantino Lorenzo 
Published: October 2021

Innovation and technology have led to the redefinition of business models and development of new ones in many bricks and mortar sectors. Similarly, blockchain and fintech have impacted the finance and banking industries and are expected to further affect them in the future, leading some media to coin the expression “Uberization of banking”. The authors extrapolate from sharing economy models to conclude that while blockchain and fintech are poised to advance finance and banking, there are no disruptive features that corroborate the term. By analogy and successive approximations, this article identifies the limitations of the arguments for disruption in finance and banking. Besides, hinging upon stylized facts, the article establishes similarities with sharing economy models to identify potential threats stemming from financial innovations such as Tokenomics, tagged as “no-ABSs”. Eventually, the authors identify entry points and ways forward arising from the COVID-19 pandemic for policy makers and regulators to regain their pivotal role in policing the market and ensuring transparency while driving innovation.
INFORMATION AND MATHEMATICAL STRUCTURES CONTAINED IN THE NATURAL LANGUAGE WORD DOMAINS AND THEIR APPLICATIONS
Authors: Ho Nguyen Cat 
Published: October 2021

The study stands on the standpoint that there exist relationships between real-world structures and their provided information in reality. Such relationships are essential because the natural language plays a specifically vital and crucial role in, e.g., capturing, conveying information, and accumulating knowledge containing useful high-level information. Consequently, it must contain certain semantics structures, including linguistic (L-) variables’ semantic structures, which are fundamental, similar to the math variables’ structures. In this context, the fact that the (L-) variables’ word domains can be formalized as algebraic semantics-based structures in an axiomatic manner, called hedge algebras (HAs,) is still a novel event and essential for developing computational methods to simulate the human capabilities in problem-solving based on the so-called natural language-based formalism. Hedge algebras were founded in 1990. Since then, HA-formalism has been significantly developed and applied to solve several application problems in many distinct fields, such as fuzzy control, data classification and regression, robotics, L-time series forecasting, and L-data summarization. The study gives a survey to summarize specific distinguishing fundamental features of HA-formalism, its applicability in problem-solving, and its performance.
USING COMBINATORIAL MAPS FOR ALGORITHMS ON GRAPHS
Authors: Cori Robert 
Published: October 2021

The aim of this paper is to come back to a data structure representation of graph by permutations. This originated in the years 1960-1970 by contributions due to J. Edmonds [7], A. Jacques [11], W. Tutte [22] in order to consider the embedding of a graph in a surface as a combinatorial object. Some algebraic developments where suggested in [4] and [12]. It was also used for implementation in different situation, like planarity testing by H. de Fraysseix and P. Rosenstiehl [6], computer vision by G. Damiand and A. Dupas [5] or formal proofs by G. Gonthier [9].
Automedicação em idosos da Atenção Básica
Authors: Silva Thalita Cristinny Araujo , Júnior Francisco das Chagas Candeira Mendes , Silva Jefferson Carlos Araujo , Carvalho Jeane de Sousa , Ribeiro Mara Dayanne Alves , Biângulo Fernando Barcellar 
Published: October 2021

OBJETIVO: Descrever a prática da automedicação em idosos atendidos na Atenção Básica. MÉTODO: Estudo transversal, descritivo e exploratório realizado com idosos adscritos na Estratégia Saúde da Família (ESF) Mutirão do município de Cocal, Piauí. Foram incluídos idosos com autonomia física e funcional. Os dados foram coletados por meio da aplicação de um questionário contendo dados sociodemográfico e dados relacionados à prática da automedicação. A análise se deu pela estatística descritiva. RESULTADOS: Um total de 35 idosos integraram a amostra, com média de idade 70 (± 6,6) anos e predominância do sexo feminino (65,7%). Verificou-se que 80% dos participantes referiram fazer uso de medicações de maneira regular, 62,8% não receberam informações sobre os perigos da automedicação, 68,6%toma remédios sem prescrição médica e 48,6% usa medicação indicada por vizinho/amigo/parente. Quadros álgicos seguido da gripe/resfriado foram os motivos mais comuns da automedicação. A orientação farmacêutica (74,3%) e ter resolvido o problema de saúde antes da consulta médica (68,6%) estão entre as causas que favoreceram a referida pratica. CONCLUSÃO: Os dados sugerem que a automedicação entre os idosos é comum, principalmente em quadros álgicos e resfriados, e que a dificuldade de acesso à consulta médica, orientação farmacêutica e o desconhecimento dos perigos predispõem a esta prática.
Subjectivities in curricular practices in Mathematics in Youth and Adult Education
Authors: Freitas Adriano Vargas , Andrade Eliane Lopes Werneck de , Xavier Francisco Josimar Ricardo 
Published: October 2021

Background: The curriculum practices, especially those related to Mathematics, developed in EJA, can exert a strong influence on the students' sentiment of self-efficacy and, in turn, influence the cognitive processing of mathematical knowledge. Objective: To investigate which meanings of curricular practices in Mathematics are subjectived by EJA teachers. Design: Narratives of 5 teachers who work at EJA, whose data collection was through interviews. Environmente and participants: The research took place in a rural municipal public school located in a city in the interior of Ceará. Data collection and analysis: Textual Discursive Analysis. Results: The curricular practices developed in EJA, especially those related to mathematics, can exert a strong influence on the student's sentiment of self-efficacy and influence their cognitive processing of mathematical knowledge. The moments of collective pedagogical planning and training influence the selection of curriculum content and teaching materials, guiding the construction of the teachers' curricular practices, influencing the construction of their subjectivities, in a permanent relationship between subjects who interact and confront each other from different ways for their pedagogical work, including the support they seek from their peers. Conclusions: Thinking about the subjectivities of the actors involved in EJA should mean turning the attention to the teaching and learning processes, which encompass a range of diversities of social groups with very different cultures, expectations, ages and interests, meaning greater attention to production and implementation of appropriate curricula and teaching for these groups of students, considering their cultures, experiences and previous experiences.
History of controlled trials in medicine: real priorities are little-known. Report 2. From early experiments to the present day: without alternation and randomization
Authors: Koterov A. N. , Tikhonova O. A. , Ushenkova L. N. , Biryukov A. P. 
Published: October 2021

The aim of the three-report review is the historical development of clinical trials, controlled trials (CT) and randomized controlled trials (RCT), and the inclusion of these approaches in health-related disciplines (Medicine and Epidemiology). Report 2 provides a description of the wellknown James Lind Library (JLL), as well as a formed database of sources on the theme. JLL was internationalized, although most of the papers belong to authors from the UK. Many studies on the history of CT and RCT are reflected in JLL publications, but remain unclaimed without changing on common milestones and priorities. Besides, the formed base of sources included 9 studies not reflected in the JLL, of which three are principled. Six of them are given in Report 2.Half of historical milestones on the theme (168 in total) belong to the United Kingdom, 23% to the United States, and 4% to the Italy. The remaining 19 countries, ancient, medieval and modern, contribute 0.6–4% (Russia – 1.2% by the 20th century). The earliest source on the history of CT is J.P. Bull’s dissertation (1951). The formed database as of July 2020 contained more than 260 publications, and only 9 of them were Russian (2005–2018). The base includes 7 western dissertations on the history of CT.The object of the Report 2 study was CT as such, without any attempts at randomization or even quasi-randomization by alternate allocation. The most comprehensive thematic table on non-randomized CTs has been compiled, including studies from the Chinese emperor Shen Nung (2373 BC) and the prophet Daniel (6th century BC), to BCG vaccination for children of Canadian Indians (1941–1949). PubMed search on ‘non-randomized controlled trial’ was made. For the period of 1990–2020 years, 303 publications were found (up to 32 papers in 2020). Compared to RCT, the number of such studies is small (estimated at 0.08%), but it is important to have an appropriate conjuncture in the modern period. Along with the fact that most of the drugs and therapies currently in use are developed without RCT, the revealed ‘immortality’ of CT, even without quasi-randomization, can have social significance, removing complexes and embarrassment in cases where neither RCT nor even quasi-RCT is possible, but social and public needs require the immediate receipt of at least an approximate answer to hot questions of public health (for example, in 2020).
Mental Disorders, Gun Ownership, and Gun Carrying Among Soldiers After Leaving the Army, 2016–2019
Authors: Bossarte Robert M. , Ziobrowski Hannah N. , Benedek David M. , Dempsey Catherine L. , King Andrew J. , Nock Matthew K. , Sampson Nancy A. , Stein Murray B. , Ursano Robert J. , Kessler Ronald C. 
Published: October 2021

Objectives. To examine associations of current mental and substance use disorders with self-reported gun ownership and carrying among recently separated US Army soldiers. Veterans have high rates of both gun ownership and mental disorders, the conjunction of which might contribute to the high suicide rate in this group.Methods. Cross-sectional survey data were collected in 2018–2019 from 5682 recently separated personnel who took part in the Army Study to Assess Risk and Resilience in Servicemembers. Validated measures assessed recent mood, anxiety, substance use, and externalizing disorders. Logistic regression models examined associations of sociodemographic characteristics, service characteristics, and mental disorders with gun ownership and carrying.Results. Of the participants, 50% reported gun ownership. About half of owners reported carrying some or most of the time. Mental disorders were not associated significantly with gun ownership. However, among gun owners, major depressive disorder, panic disorder, posttraumatic stress disorder, and intermittent explosive disorder were associated with significantly elevated odds of carrying at least some of the time.Conclusions. Mental disorders are not associated with gun ownership among recently separated Army personnel, but some mental disorders are associated with carrying among gun owners. (Am J Public Health. 2021;111(10):1855–1864. https://doi.org/10.2105/AJPH.2021.306420 )
Rebuilding a US Federal Data Strategy After the End of the “Community Health Status Indicators”
Authors: Phillips Robert L. , Kanarek Norma F. , Boothe Vickie L. 
Published: October 2021

For nearly 2 decades, the Community Health Status Indicators tool reliably supplied communities with standardized, local health data and the capacity for peer-community comparisons. At the same time, it created a large community of users who shared learning in addressing local health needs. The tool survived a transition from the Health Resources and Services Administration to the Centers for Disease Control and Prevention before being shuttered in 2017. While new community data tools have come online, nothing has replaced Community Health Status Indicators, and many stakeholders continue to clamor for something new that will enable local health needs assessments, peer comparisons, and creation of a community of solutions. The National Committee on Vital and Health Statistics heard from many stakeholders that they still need a replacement data source. (Am J Public Health. 2021;111(10):1865–1873. https://doi.org/10.2105/AJPH.2021.306437 )
PV Loops and REBOA During Hemorrhage and Resuscitation
Authors: Stonko David P , Edwards Joseph , Abdou Hossam , Elansary Noha N , Lang Eric , Savidge Samuel G , Treffalls Rebecca N , Morrison Jonathan J 
Published: October 2021

Abstract
Retrograde Endovascular Balloon Occlusion of the Aorta (REBOA) is frequently used in hemorrhagic shock to facilitate resuscitation. In theory, aortic occlusion increases afterload and focuses perfusion to the coronary arteries and great vessels; also to focus perfusion to the brain. It is, however, unknown exactly how and to what extent REBOA impacts cardiovascular parameters such as preload, afterload and contractility, or coronary artery blood flow. It is also not known how these parameters evolve over time during REBOA as it is shifted from fully to partially occlusive, or weaned down entirely. We aim to use left ventricular Pressure-Volume (PV) loop analysis and directly measure coronary flow in swine as they descend into hemorrhagic shock, are resuscitated with full aortic occlusion with REBOA, transitioned to partial aortic occlusion with REBOA, and then weaned completely off of the REBOA and are resuscitated. We will examine, specifically, measures of preload, afterload, contractility and coronary blood flow during each study time period (baseline, hemorrhagic shock, full aortic occlusion, partial aortic occlusion, and post-occlusion during resuscitation).
Integrated PCR testing and extended window contact tracing system for COVID-19 to improve comprehensiveness and speed
Authors: Raymenants Joren , Geenen Caspar , Thibaut Jonathan , Gorissen Sarah , Nelissen Klaas 
Published: October 2021

Abstract
Testing and contact tracing are standard tools for controlling the spread of COVID-191. Their effectiveness hinges on a sequence of processes encompassing testing coverage and timeliness, testing quality and speed of reporting, contact tracing speed and comprehensiveness and compliance with advice given2–6. We optimized this sequence of processes in the context of a public health program targeting around 33,000 higher education students through a combination of low barrier PCR testing with rapid turn-around-time, close integration of testing and tracing teams and IT infrastructure, community engagement and the implementation of bidirectional contact tracing by extending the contact tracing window from 2 to 7 days before symptom onset or test of the index case. We anticipate this combined intervention to help improve epidemic control.
Risk Classification of Human Papillomavirus-related Oropharyngeal Squamous Cell Carcinoma in Japanese Patients
Authors: ITAMI Jun , KOBAYASHI Kenya , MORI Taisuke , HONMA Yoshitaka , KUBO Yuko , MURAKAMI Naoya , OMURA Go , OKUMA Kae , INABA Koji , TAKAHASHI Kana , KASHIHARA Tairo , SHIMIZU Yuri , TAKAHASHI Ayaka , NAKAYAMA Yuko , MATSUMOTO Fumihiko , YOSHIMOTO Seiichi , IGAKI Hiroshi 
Published: October 2021

Abstract
Purpose The validity of the risk classification according to Ang for human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) remains to be studied in patients treated by methods other than chemoradiotherapy and in Japanese patients. In this study, the validity of Ang's risk classification was studied in Japanese patients treated using various methods, including surgery.Material and Method Between 2010 and 2018, 122 patients with HPV-related OPSCC stages III and IV according to the TNM classification 7th edition (TNM-7) were treated curatively at a single institution in Japan. The median age was 62.7 years. Sixty-seven patients (54.9%) were classified as stage I according to the TNM 8th edition (TNM-8). Over 50% of the patients underwent surgery with or without adjuvant therapy. The influence of multiple factors on survival was determined.Results Age, amount of smoking, secondary cancer, and N-stage according to the TNM-7 significantly influenced survival. Ang's risk classification was also predictive of prognosis, but if 30 pack-years (PYs) instead of 10 PYs is employed to dichotomize the amount of smoking, the new risk classification can significantly better predict prognosis. According to the new risk classification, favorable and unfavorable risk patients showed 5-year progression-free survival, disease-specific survival, and overall survival rates of 72.7% and 35.9%, 94.6% and 76.2%, and 92.6% and 62.7%, respectively.Conclusions Even in patients treated by methods other than chemoradiotherapy and in Japanese patients, the combination of the amount of smoking and neck node status is useful in prognosis prediction.
The Clinical Evaluation of IIA Balloon Occlusion for Pernicious Placenta Previa Patients with Placenta Accreta: A Retrospective Study
Authors: Hong Ling , Chen Aner , Chen Jinliang , Li Xiuxiu , Zhuang Wenming , Shen Yijing , Dai Qiaohong , Zhang Li 
Published: October 2021

Abstract
Objective: This study aimed to evaluate the clinical efficacy of internal iliac artery(IIA) balloon occlusion in patients with pernicious placenta previa coexisting with placenta accreta. Background: Pernicious placenta previa is frequently reported to be complicated with placenta accreta, which contributes to serious consequences such as severe obstetric postpartum hemorrhage or even maternal mortality. Methods: Fifty-eight pernicious placenta previa patients complicated with placenta accreta were retrospectively reviewed. The ballon group consisted of 23 patients, who underwent a caesarean delivery with internal iliac artery occlusion. 35 patients were in the control group, who had a standard caesarean delivery. The primary outcomes were estimated blood loss (EBL), cesarean hysterectomy, and blood transferring volume. The secondary outcomes were operating time, intraoperative hemostatic approaches, surgical complications, balloon catheter–related complications, length of maternal stay, cost of hospitalization, and neonatal outcomes.Results: No difference was observed in estimated blood loss (EBL), blood transferring percentages and volume, additional measures to secure hemostasis , surgical complications, hospital stay postoperatively and newborn outcomes. More than 40% of the balloon group underwent hysterectomy because of uncontrollable postpartum bleeding (10[43.48%] vs. 11[31.43%],P=0.350).Complications related to occlusion of IIA did not occur.The duration of the surgery of the balloon group was significantly longer than that of the control group(123.52 min±74.76 versus 89.17±48.68,P=0.038), and the total hospitalization cost was also significantly higher than that of the control group(45116.67±9358.67 yuan versus 30615.41±11587.44yuan,P=0.000).Conclusion: IIA balloon occlusion in patients with pernicious placenta previa coexisting with placenta accreta did not reduce the hysterectomy rate during cesarean section, nor did it reduce blood loss and blood transfusion, but it prolonged the duration of the surgery and increased the total cost.