bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chloroplast genome and historical biogeography of the three Magnolias
Authors: zhang min , guo shuai , Yanpeng YIN , ZHOU Luojing , Bo REN , Li WANG , SHI Xiaodong , Feixia HOU , Cheng PENG , Xianmei YIN , Jihai GAO 
Published: March 2021

Abstract
Magnolia officinalis, M. officinalis subsp.biloba and M. hypoleuca are all typical medicinal plants, belonging to genus Magnolia and Family Magnoliaceae. Their molecular information, particularly genetic difference, were known less. In this study, the platform Illumina HiSeq was used to sequence and assemble a novel cp (chloroplast) genome of M. hypoleuca followed by cp purification. Combined with two published cp rawdata, gene cycles and function annotations were comparably performed for the three plant species. The results indicated that 19 791 019 clean reads was assembled for M. hypoleuca cp, Q30 being 91.33%, and genome 160 051 bp. Its GC content is 39.2%, including 37 tRNAs and 8 rRNAs. The M. hypoleuca had smaller chloroplast genome and more introns (or exons) than M. officinalis and M. officinalis subsp.biloba. And there were respectively 11 and 8 more functional genes in M. hypoleuca cp than that in the other two. Based on cp complete genomes sequences, we constructed the phylogenetic relationship and estimated the divergence time of the three species by ML (Maximum likelihood) method, with other 10 published Magnoliaceae species. The results showed that M. officinalis subsp.biloba and M. officinalis might diverge from M. hypoleuca around 18.98 Ma, then they diverged from each other around 15.00 Ma. Additionally, the middle Miocene warming period might play an important role in the demographic and evolutionary histories of the three Magnolias, which provided a novel insight of the origin and dispersal routes of M. hypoleuca.
Does General Comorbidity Impact the Postoperative Outcomes After Surgery for Large and Giant Petroclival Meningiomas?
Authors: Roux Alexandre , Troude Lucas , Baucher Guillaume , Bernard Florian , Pallud Johan , Roche Pierre-Hugues 
Published: March 2021

Abstract
ObjectiveWe assessed the role of the general condition of the patient in addition to usual anatomical reasoning to improve the prediction of personalized surgical risk for patients harbouring a large and giant petroclival meningiomas.MethodsSingle-center, retrospective observational study including adult patients surgically treated for a large and giant petroclival meningioma between January 2002 and October 2019 in a French tertiary neurosurgical skull-base center by one Neurosurgeon. Inclusion criteria were: 1) histopathologically proven meningioma; 2) larger than 3cm in diameter; 2) located within the upper two-thirds of the clivus, the inferior petrosal sinus, or the petrous apex around the trigeminal incisura, medial to the trigeminal nerve. Clinical and radiological characteristics were gathered preoperatively including ASA score, the modified Frailty Index and the Charlson Comorbidity Index. Post-operative severe neurological and non-neurological complications were collected.ResultsA total of 102 patients harbouring a large and giant petroclival meningioma were included. The rate of postoperative death was 3.0% related to a congestive heart failure (n=1), a surgical site hematoma (n=1), and an ischemic stroke (n=1). A severe neurological impairment was found in 12.8% and a severe non-neurological morbidity was found in 4.0%. The overall rate of severe morbidity and mortality was 15.7% after large and giant petroclival meningioma surgery. The presence of brainstem peri-tumoral edema (adjusted OR, 4.83 [95% CI 1.84–7.52], p=0.028) was independently associated with a history of postoperative severe neurological morbidity. Male gender (adjusted OR, 7.42 [95% CI 1.05–49.77], p=0.044), major cardiovascular morbidity (adjusted OR, 9.5 [95% CI 1.05–86.72], p=0.045), and an ASA score ≥ 2 (adjusted OR, 11.09 [95% CI 1.46–92.98], p=0.038) were independently associated with a history of postoperative severe non-neurological morbidity. A modified Frailty index ≥ 1 (adjusted OR, 3.13 [95% CI 1.07–9.93], p=0.047), and a low neurosurgical experience (adjusted OR, 5.38 [95% CI 1.38–20.97], p=0.007) were independently associated with a history of postoperative overall morbidity and mortality.ConclusionsThis study suggests to add scores assessing the patient general condition in daily practice to improve the selection of patients eligible for surgery. Collaborative international multicenter studies will be necessary to confirm these results and allow their implementation in clinical routine.
Unusual competition of superconductivity and charge-density-wave state in a compressed topological kagome metal
Authors: Yu Fanghang , Ma Donghui , Zhuo Weizhuang , Liu Shiqiu , Wen Xikai , Lei Bin , Ying Jianjun , Chen Xianhui 
Published: March 2021

Abstract
Understanding the competition between superconductivity and other ordered states (such as antiferromagnetic or charge-density-wave (CDW) state) is a central issue in condensed matter physics. The recently discovered layered kagome metal AV3Sb5 (A = K, Rb, and Cs) provides us a new playground to study the interplay of superconductivity and CDW state by involving nontrivial topology of band structures. Here, we present high-pressure electrical transport measurements for CsV3Sb5 with the highest Tc of 2.7 K in AV3Sb5 family. The CDW transition is monotonically suppressed by pressure, while superconductivity is enhanced with increasing pressure up to P1 ≈0.7 GPa, then an unexpected suppression on superconductivity happens until pressure around 1.2 GPa. The CDW is completely suppressed at a critical pressure P2≈2 GPa together with a maximum Tc of about 8 K. In contrast to a common dome-like behavior, the pressure-dependent Tc shows an unexpected double-peak behavior. The unusual suppression of Tc at P1 is linked to a Lifshitz transition of Fermi surface evidenced by quantum oscillation experiment, a sudden enhancement of the residual resistivity and a rapid decrease of magnetoresistance. A possible nearly commensurate CDW state involving the formation of CDW domain wall has been used to account for the Lifshitz transition. Our discoveries indicate an unusual competition between superconductivity and CDW state in pressurized kagome lattice.
Radio-Over-Fiber Dual-Parallel Mach-Zehnder Modulator System for Photonic Generation of Millimeter-Wave Signals Through Two Stages
Authors: Sousa Fabio Barros de , Sousa Fiterlinge M. de , Miranda Igor R. S. , Paschoal Waldomiro , Costa Marcos B. C. 
Published: March 2021

Abstract
In this work, we presented a radio-over-fiber (ROF) access network through two modulation stages for the generation of multiple millimeter wave (mm-wave) signals with frequencies of 20GHz, 40GHz, 60GHz and 80 GHz for the transmission rate of 10 Gbps as a function of the variation of link distance and signal power. The specific purpose of the paper was to design and to investigate a RoF system based on the variation of mm-wave frequencies in order to implement a simple and effective system. In stage 1, there are two modulators in parallel (MZMa and MZMb) called dual-parallel Mach-Zehnder modulator (DP-MZM) and in stage 2 there is only one modulator (MZMc), connected to three pulse generators: Non-Return-to-Zero (NRZ), Return-to-Zero (RZ). A single-mode fiber (SMF) and Gaussian and an erbium-doped fiber amplifier (EDFA) were also used to send signals to base stations (BSs). The numerical analyzes of the results of the eye diagrams showed excellent bit error rate (BER) and quality factor (Q-factor) values, which proved the good performance of the proposed ROF DP-MZM system, for the three encoding formats used, which was able to generate 3-tupling mm-wave for multiple wireless accesses.
Fast 6D Object Pose Estimation of Shell Parts for Robotic Assembly
Authors: Hu Haopeng , Gu Weikun , Yang Xiansheng , Zhang Nan , Lou Yunjiang 
Published: March 2021

Abstract
Shell parts which have similar and close inner and outer surfaces are common in industrial manufacturing applications. In view of the 6D pose error compensation of parts in high-precision robotic assembly tasks, this work proposes a fast 6D pose estimation approach tailored for shell parts. With a binocular structured light camera, the proposed approach consists of two phases, namely initial pose estimation phase and local pose estimation phase. In the former one, an initial pose correction and translation offset methods serve to solve the local optimal estimation problem of the iterative closest point (ICP) algorithm. This problem is caused by the poorly assigned initial pose and the similar inner and outer surfaces of shell parts. In the latter one, the voxel sampling and the weighted point-to-plane ICP algorithms are applied to boost the efficiency of the pose estimation approach. With two typical shell parts, a simulation and an experiment of pose estimation are conducted to verify the effectiveness of the proposed approach. Experiment results prove that the accuracy of the pose estimation approach is 0:27mm/0:38°, and the runtime is 680ms.
Liquefaction Susceptibility of an Earth Dam Foundation: A Case Study&nbsp;
Authors: karoui Hatem , Bouassida Mounir 
Published: March 2021

Abstract
Sidi El Barrak earth dam is a compacted earth embankment of height 28 m built in 1999 on a heterogeneous foundation with strong dominance of sandy formations. The dam foundation was subjected to several tests to predict its behavior against the liquefaction risk. Standard penetration test (SPT) results served to evaluate the liquefaction risk in an earthquake occurrence. This article, firstly, presents an interpretation of data collected from SPT tests. Determination of liquefaction risk resulted from the empirical methods proposed by Seed & Idriss, (1985) and Idriss & Boulanger, (2008). Obtained results by those methods showed that, for different earthquake magnitudes equal to 5.25, 6 and 6.75, the risk of liquefaction exists in the pure sand layer located between the ground surface and 15 m depth of the foundation of the earth dam. An UBC3D-PLM constitutive model was adopted for studying the numerical response of sand layer subjected to an earthquake of acceleration equal 0.2 g to estimate its liquefaction risk. Recorded SPT data and laboratory tests results served for the determination of geotechnical parameters of this model. From numerical predictions it revealed that the liquefaction risk is greater for an earthquake characterized by an acceleration equal 0.2g.
HBV&nbsp;Infection Statuses Indicate Different Risks of Synchronous and Metastasis Liver Metastasis in Colorectal Cancer
Authors: Zhou Jiaming , Huang Pinzhu , Guo Xiaoyan , Tan Shuyun , Lin Rongwan , Zhan Huanmiao , Wu Xiaofeng , Peng Shaoyong , Li Tuoyang , Huang Mingzhe , Xiao Yuanlv , Wang Jianping , Huang Meijin 
Published: March 2021

Abstract
Background: Previous studies on the effect of HBV infection on CRLM are contrary. This study identified more specific and different impacts of HBV on CRLM.Methods: A total of 3132 CRC patients were analyzed retrospectively and followed up for five years. All patients were divided into three groups: group A, HBsAg positive with HBV infection; group B, HBsAg negative with HBV infection; and group C, no HBV infection. The risk factors for SYN-CRLM, MET-CRLM, 5-year OS, and LDFS were analyzed.Results: A total of 829 patients had CRLM. SYN-CRLM was found in 425 patients. The incidence of SYN-CRLM was 16.95%, 11.60% and 13.50% (P <0.03) in groups A, B, and C, respectively. HBsAg-positive HBV infection increased the risk of SYN-CRLM (P<0.01), with a worse prognosis in group A (P<0.05). MET-CRLM was found in 404 patients. The incidence of MET-CRLM in groups A, B, and C, was 16.51%, 11.53% and 16.50% (P=0.02). HBsAg-negative HBV infection decreased the incidence of MET-CRLM (P=0.02) with a better 5-year LDFS (P=0.01), but was not related to 5-year OS (P=0.15).Conclusion: HBsAg positivity infection increased the risk of SYN-CRLM with poor prognosis. HBsAg-negative infection reduced the risk of MET-CRLM with better LDFS after surgery.
Glide Path Enlargement of Curved Molar Canals Using HyFlex EDM Glide Path File versus PathFile: A Comparative Study of Preparation Time and Postoperative Pain
Authors: Han Yi , Hou Xiao-Mei 
Published: March 2021

Abstract
Background: This randomized clinical trial aimed to compare the preparation time and severity of postoperative pain between the HyFlex Electric Discharge Machine (EDM) Glide Path File (GPF) and PathFile.Methods: Eighty patients who were treated by the same specialist were enrolled. After access cavity preparation, the patients were randomly assigned to receive glide path enlargement with either HyFlex EDM GPF or PathFile. ProTaper Next X1 and X2 files were used to prepare the canals. The time of preparation was assessed and the severity of postoperative pain over the next 7 days was recorded. The preparation time and the postoperative pain scores were compared using one-way analysis of variance (ANOVA) (P ≤ 0.05).Results: Glide path enlargement was significantly shorter with HyFlex EDM GPF (27.828 ± 2.345 s) than with PathFile (48.942 ± 2.864 s) (P < 0.001). The highest postoperative pain score was recorded on the first day and the pain decreased over time in both groups. GPF group patients reported significantly less postoperative pain than PathFile group patients overall (P < 0.05).Conclusion: Postoperative pain and glide path preparation time could be reduced by using the HyFlex EDM GPF system.Trial registration: PKUSSNCT, PKUSSNCT-17B12, Registered 24 October 2017
Molecular Surveillance of Shiga Toxigenic Escherichia coli in selected beef abattoirs in Osun State Nigeria
Authors: Ayoade Femi , Oguzie Judith , Eromon Philomena , Omotosho Omolola , Ogunbiyi Tosin , Olumade Testimony , Folarino Onikepe , Happi Christian 
Published: March 2021

Abstract
Shiga toxigenic strains of E. coli (STEC) known to be etiological agents for diarrhea were screened for their incidence/ occurrence in selected abattoirs and retail meat sources in Osogbo metropolis of Osun State, Nigeria using a randomized block design. Samples were plated directly on selective and differential media and confirmed serologically using latex agglutination serotyping kit, then, multiplex PCR analysis was used to screen for the presence of specific virulence factors. The results showed a percent occurrence of STEC at the sampled sites ranging from 25.8–46.3%. None of the strains showed any visible agglutination with the O157 latex reagent. Sequence analysis of PCR products was performed on a representative isolate showing the highest combination of virulence genes. This sequence was subsequently submitted to GenBank with accession number MW463885. The sequence showed 100% coverage and 96.46% percentage identity with Escherichia coli O113:H21 (GenBank Accession number: CP031892.1) strain from Canada. From evolutionary analyses, the strain from Nigeria, sequenced in this study, is evolutionarily distant when compared with the publicly available sequences from Nigeria. Although no case of E. coli O157 was found within the study area, percent occurrence of non-O157 STEC as high as 46.3% at some of the sampled sites is worrisome and requires regulatory interventions in ensuring hygienic practices at the abattoirs within the study area.
Integrating Life Cycle Assessment Into Landscape Studies: A Postcard From Hulunbuir
Authors: Wu Susie Ruqun , Liu Xinchao , Wang Lulu , Chen Jiquan , Zhou Peiling , shao changliang 
Published: March 2021

Abstract
ContextConventional life cycle assessment (LCA) has been increasingly criticized for lacking spatial information, especially for agricultural systems where high spatial sensitivity is present.ObjectivesThe objective of this research is twofold: first, to assess the potential environmental impacts and the production efficiency of pastoralism farming, and, second, to identify the influence of the spatial distribution of farms on the environmental impacts, if any. MethodsA cradle-to-gate spatialized agricultural LCA was conducted for 45 farms surveyed from the Hulunbuir Grassland by splitting direct onsite processes from upstream processes, adopting the spatialized characterization factors (SCFs) of IMPACT World+.ResultsContrasting results were observed for different impact categories regarding whether upstream or onsite processes served as the environmental hotspot. While direct onsite animal emissions did not show spatial dependence at the inventory stage, its resulting impact scores demonstrated the most contrasting spatial patterns among various impact categories, depending on whether and how spatial resolution and location were introduced during the LCIA stage.ConclusionsA cradle-to-gate spatialized agricultural LCA was proposed and applied to assess the environmental impacts of pastoralism farming in Hulunbuir Grassland. The overall spatial dependence of the LCA results was weak, if present, it depended on the interactions between spatial variation within the life cycle inventory and the spatial resolution and location of the SCFs. Environmental burden shifting occurred between different impact categories, and it remains a policy challenge as how to increase the production efficiency in the pastoralism system.
Effects of Calcination Temperature and Chemical Modification on the Adsorption of Cd and As(V) by Biochar Derived from Pteris Vittata
Authors: Sugawara Kazuki , Ichio Kouhei , Ichikawa Yumiko , Ogawa Hitoshi , Suzuki Seiichi 
Published: March 2021

Abstract
Phytoremediation can be applied successfully to solve the serious worldwide issue of arsenic (As) and cadmium (Cd) pollution. However, the treatment of biomass containing toxic elements after remediation is a challenge. In this study, we investigated the effective use of biomass resources by converting the As hyperaccumulator P. vittata into biochar to adsorb toxic elements. Plant biomass containing As was calcined at 600 °C, 800 °C, and 1200 °C and its surface structure and adsorption performances for As and Cd were evaluated. Calcination at 1200 °C increased the specific surface area of the biochar, but it did not significantly affect its adsorption capacity for toxic elements. The calcined biochar had very high adsorption capacities of 90% and 95% for As and Cd, respectively, adsorbing 450 mg/g-biochar of both elements. The As adsorption rate was improved by FeCl3 treatment. However, the adsorption capacity for Cd was not significantly affected by the NaOH treatment. In conclusion, it was found that after phytoremediation using P. vittata biomass, it can be effectively used as an environmental purification material by conversion to biochar. Furthermore, chemical modification with FeCl3 improves the biochar’s adsorption performance.
Enhancement of sewage sludge dewaterability by fungal conditioning with Penicillium simplicissimum NJ12: From bench- to pilot-scale consecutive multi-batch investigations
Authors: Tao Neng , Wu Xiu , Zhang Feng , Pi Zilei , Wen Jiaqi , Fang Di , Zhou Lixiang 
Published: March 2021

Abstract
Bench- and pilot-scale successive multi-batch trials were conducted to investigate the performance and sustainability of fungal conditioning with Penicillium simplicissimum NJ12 for improving sludge dewatering. The dominant factors affecting the sludge dewaterability improvement by P. simplicissimum NJ12 were also identified. Fungal treatment with P. simplicissimum NJ12 at a volume fraction of 5% of the inoculum greatly improved the sludge dewaterability. This improvement was characterized by sharp decreases in the specific resistance to filtration from 1.97 × 1013 to 3.52 × 1011 m/kg and capillary suction time from 32 to 12 s within 3 days. Stepwise multiple linear regression analysis showed that a marked decrease (58.8%) in the protein content in slime extracellular polymeric substances and an increase in the zeta potential of the sludge (from − 35 to − 10 mV) were the most important factors that improved the dewaterability of sludge after fungal treatment. Consecutive processes of fungal treatment could be realized by recirculating the fungal-treated sludge with a recycling rate of 1:2 (Vbiotreated sludge/Vtotal sludge). The treatment effectiveness was maintained only over three successive cycles, but replenishment with fresh P. simplicissimum NJ12 would be provided periodically at set batch intervals. These findings demonstrate the possibility of P. simplicissimum NJ12-assisted fungal treatment for enhancing sludge dewatering.
Deployment of Workforce in Global Health: What are the Priorities for China?
Authors: Ma Xuejiao , Ding Wei , Qian Yingjun , Lu Shenning , Wang Bei , Xu Qiuli , Wang Duoquan , Guan Yayi , Xiao Ning , Zhou Xiaonong 
Published: March 2021

Abstract
BackgroundChina has increasingly emerged as an important player in global health. However, compared to the developed countries, China still lacks the sufficient human resources for global health engagement with limited necessary qualified capacity. The priorities for the deployment of Chinese workforce in global health engagement remains unclear. This study aims to identify the priorities of the deployment of Chinese global health workforce by exploring the core competencies for Chinese global health workforce, factors influencing the deployment and the approach of deployment. MethodA total of 148 key stakeholders from 10 provinces in China conducting global health program during the recent 3 years were selected as the study sample. A structured questionnaire was developed to collect the data on four aspects, including the general information, core competencies, factors influencing deployment, and the deployment way. The questionnaire was distributed to the respondents through an online survey tool. All original data was exported to Microsoft Excel 2010 to calculate the frequency and percentage of every option. The descriptive analysis was made on the priorities of deployment of Chinese global health workforce. ResultsMore than half of respondents 51.4% (76/148) regarded “communication” as the most important competency of Chinese global health workforce while a large portion of Chinese Embassies 50.0% (6/12) and international organizations 75.0% (12/16) believed that “professional skills” was the paramount. In addition, 58.1% (86/148) of the participants agreed that incentive factors (salary, professional title, etc.) are the first factors influencing the deployment, whereas, a majority of 75% (12/16) international organization stakeholders emphasized “security” as the foremost factor. Furthermore, 60.8% (90/148) thought that staff should be deployed align with the needs of global health program implementation. ConclusionThe study shows the priorities of the deployment of Chinese global health workforce, including strengthening the competency of communication and professional skills, stressing the personal security and incentives, and catering to the program implementation.