bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Precursor Phase of an X-class Flare: Magnetic Reconnection, Powering and Non-thermal Electrons
Authors: Shen Jinhua , Ji Haisheng , Su Yingna 
Published: November 2021

Abstract
In this paper, we report three interesting phenomena that occurred during the precursor phase of the X1.6 class flare on 2014 September 10. (1) The magnetic reconnection initiating the flare occurs between one of the two J-shaped magnetic flux ropes that constitute a sigmoidal structure and the overlying sheared magnetic arcade that runs across the sigmoid over its middle part. The reconnection formed an erupting structure that ultimately leads to flare onset. Another J-shaped magnetic flux rope remains unaffected during the whole eruption. The phenomenon is revealed by the observation made by the Atmospheric Imaging Assembly on board the Solar Dynamic Observatory (SDO) at 94 and 131 Å. (2) Being simultaneously with starting time of the precursor, photospheric vertical electric current (VEC) around the footpoint region of the overlying magnetic arcade underwent an obvious increase, as observed by the Helioseismic and Magnetic Imager (HMI) on board SDO. By only taking into account the VEC with current density over 3σ value (1σ: 10 mA m−2), we are able to pick out precursor-associated VEC increase starting from nearly the level of zero. We regard it as a kind of powering process for the magnetic reconnection between the two magnetic loops. (3) With high-resolution narrow-band Helium 10830 Å images taken by Goode Solar Telescope at Big Bear Solar Observatory (BBSO), we observe a narrow absorption (dark) front that runs along the erupting magnetic structure (or the erupting hot channel) and moves in the direction of the eruption during the precursor phase. Assuming the excitation mechanism of Helium atoms along the absorption front by non-thermal electrons, the phenomenon shows that the interaction between the erupted hot channel and the overlying (or surrounding) magnetic field has yielded electron acceleration.
Epitaxial growth of CsPbBr3/PbS single-crystal film heterostructures for photodetection
Authors: Wang Yifan , Li Xuanze , Liu Pei , Xia Jing , Meng Xiangmin 
Published: November 2021

Abstract
Epitaxial high-crystallization film semiconductor heterostructures has been proved to be an effective method to prepare single-crystal films for different functional devices in modern microelectronics, electro-optics, and optoelectronics. With superior semiconducting properties, halide perovskite materials are rising as building blocks for heterostructures. Here, the conformal vapor phase epitaxy of CsPbBr3 on PbS single-crystal films is realized to form the CsPbBr3/PbS heterostructures via a two-step vapor deposition process. The structural characterization reveals that PbS substrates and the epilayer CsPbBr3 have clear relationships: CsPbBr3(110) // PbS(100), CsPbBr3[

] // PbS[001] and CsPbBr3[001] // PbS[010]. The absorption and photoluminescence (PL) characteristics of CsPbBr3/PbS heterostructures show the broadband light absorption and efficient photogenerated carrier transfer. Photodetectors based on the heterostructures show superior photoresponsivity of 15 A/W, high detectivity of 2.65 × 1011 Jones, fast response speed of 96 ms and obvious rectification behavior. Our study offers a convenient method for establishing the high-quality CsPbBr3/PbS single-crystal film heterostructures and providing an effective way for their application in optoelectronic devices.
Radiation-hardened property of single-walled carbon nanotube film-based field-effect transistors under low-energy proton irradiation
Authors: Zhang Xiaorui , Zhu Huiping , Peng Song’ang , Xiong Guodong , Zhu Chaoyi , Huang Xinnan , Cao Shurui , Zhang Junjun , Yan Yunpeng , Yao Yao , Zhang Dayong , Shi Jingyuan , Wang Lei , Li Bo , Jin Zhi 
Published: November 2021

Abstract
Strong C–C bonds, nanoscale cross-section and low atomic number make single-walled carbon nanotubes (SWCNTs) a potential candidate material for integrated circuits (ICs) applied in outer space. However, very little work combines the simulation calculations with the electrical measurements of SWCNT field-effect transistors (FETs), which limits further understanding on the mechanisms of radiation effects. Here, SWCNT film-based FETs were fabricated to explore the total ionizing dose (TID) and displacement damage effect on the electrical performance under low-energy proton irradiation with different fluences up to 1 × 1015 p/cm2. Large negative shift of the threshold voltage and obvious decrease of the on-state current verified the TID effect caused in the oxide layer. The stability of the subthreshold swing and the off-state current reveals that the displacement damage caused in the CNT layer is not serious, which proves that the CNT film is radiation-hardened. Specially, according to the simulation, we found the displacement damage caused by protons is different in the source/drain contact area and channel area, leading to varying degrees of change for the contact resistance and sheet resistance. Having analyzed the simulation results and electrical measurements, we explained the low-energy proton irradiation mechanism of the CNT FETs, which is essential for the construction of radiation-hardened CNT film-based ICs for aircrafts.
Direct calculations on the band offsets of large-lattice-mismatched and heterovalent Si and III–V semiconductors
Authors: Hu Yuying , Qiu Chen , Shen Tao , Yang Kaike , Deng Huixiong 
Published: November 2021

Abstract
Band offset in semiconductors is a fundamental physical quantity that determines the performance of optoelectronic devices. However, the current method of calculating band offset is difficult to apply directly to the large-lattice-mismatched and heterovalent semiconductors because of the existing electric field and large strain at the interfaces. Here, we proposed a modified method to calculate band offsets for such systems, in which the core energy level shifts caused by heterovalent effects and lattice mismatch are estimated by interface reconstruction and the insertion of unidirectional strain structures as transitions, respectively. Taking the Si and III–V systems as examples, the results have the same accuracy as what is a widely used method for small-lattice-mismatched systems, and are much closer to the experimental values for the large-lattice-mismatched and heterovalent systems. Furthermore, by systematically studying the heterojunctions of Si and III–V semiconductors along different directions, it is found that the band offsets of Si/InAs and Si/InSb systems in [100], [110] and [111] directions belong to the type I, and could be beneficial for silicon-based luminescence performance. Our study offers a more reliable and direct method for calculating band offsets of large-lattice-mismatched and heterovalent semiconductors, and could provide theoretical support for the design of the high-performance silicon-based light sources.
Investigation of time domain characteristics of negative capacitance FinFET by pulse-train approaches
Authors: Cai Yuwei , Zhang Zhaohao , Zhang Qingzhu , Xiang Jinjuan , Xu Gaobo , Wu Zhenhua , Gu Jie , Yin Huaxiang 
Published: November 2021

Abstract
The HfO2-based ferroelectric field effect transistors (FeFET) have been widely studied for their ability in breaking the Boltzmann limit and the potential to be applied to low-power circuits. This article systematically investigates the transient response of negative capacitance (NC) fin field-effect transistors (FinFETs) through two kinds of self-built test schemes. By comparing the results with those of conventional FinFETs, we experimentally demonstrate that the on-current of the NC FinFET is not degraded in the MHz frequency domain. Further test results in the higher frequency domain show that the on-state current of the prepared NC FinFET increases with the decreasing gate pulse width at pulse widths below 100 ns and is consistently greater (about 80% with NC NMOS) than the on-state current of the conventional transistor, indicating the great potential of the NC FET for future high-frequency applications.
Brain–computer interfaces based on code-modulated visual evoked potentials (c-VEP): a literature review
Authors: Martínez-Cagigal Víctor , Thielen Jordy , Santamaría-Vázquez Eduardo , Pérez-Velasco Sergio , Desain Peter , Hornero Roberto 
Published: November 2021

Abstract

Objective. Code-modulated visual evoked potentials (c-VEP) have been consolidated in recent years as robust control signals capable of providing non-invasive brain–computer interfaces (BCIs) for reliable, high-speed communication. Their usefulness for communication and control purposes has been reflected in an exponential increase of related articles in the last decade. The aim of this review is to provide a comprehensive overview of the literature to gain understanding of the existing research on c-VEP-based BCIs, since its inception (1984) until today (2021), as well as to identify promising future research lines. Approach. The literature review was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis guidelines. After assessing the eligibility of journal manuscripts, conferences, book chapters and non-indexed documents, a total of 70 studies were included. A comprehensive analysis of the main characteristics and design choices of c-VEP-based BCIs was discussed, including stimulation paradigms, signal processing, modeling responses, applications, etc. Main results. The literature review showed that state-of-the-art c-VEP-based BCIs are able to provide an accurate control of the system with a large number of commands, high selection speeds and even without calibration. In general, a lack of validation in real setups was observed, especially regarding the validation with disabled populations. Future work should be focused toward developing self-paced c-VEP-based portable BCIs applied in real-world environments that could exploit the unique benefits of c-VEP paradigms. Some aspects such as asynchrony, unsupervised training, or code optimization still require further research and development. Significance. Despite the growing popularity of c-VEP-based BCIs, to the best of our knowledge, this is the first literature review on the topic. In addition to providing a joint discussion of the advances in the field, some future lines of research are suggested to contribute to the development of reliable plug-and-play c-VEP-based BCIs.
Avalanche transport of energetic-ions in magnetic confinement plasmas: nonlinear multiple wave-number simulation
Authors: Zhu X.L. , Chen W. , Podestà M. , Wang F. , Liu D. , Wang Z.X. 
Published: November 2021

Abstract
Large burst activity, identified as toroidal Alfvén eigenmode (TAE) avalanche, occurs frequently in neutral-beam heated plasmas in National Spherical Torus Experiment (NSTX). Based on the typical experimental observation of TAE avalanche on NSTX, a self-consistent nonlinear multiple wave-number (k
∥ ≃ n/R, where n toroidal mode-number and R major radius) simulation associated with TAE avalanches is performed using the experimental parameters and profiles before the occurrence of TAE avalanche as the M3D-K input. The wave–wave nonlinear coupling among different modes and the resonant interaction between different modes and energetic-ions during TAE avalanches are identified in the nonlinear multiple wave-number simulations. The resonance overlap during the TAE avalanche is clearly observed in the simulation. It is found that the effective wave–wave coupling and a sufficiently strong drive are two important ingredients for the onset of TAE avalanches. TAE avalanche is considered to be a strongly nonlinear process and it is always accompanied by the simultaneous rapid frequency-chirping and large amplitude bursting of multiple modes and significant energetic-ion losses. The experimental phenomenon is observed on NSTX and is qualitatively reproduced by the simulation results in this work. These findings indicate that the onset of avalanche is triggered by nonlinearity of the system, and are also conducive to understanding the underlying mechanism of avalanche transport of energetic particles in the future burning plasmas, such as International Thermonuclear Experiment Reactor.
Recent progress in modeling ICRF-edge plasma interactions with application to ASDEX Upgrade
Authors: Zhang W. , Bilato R. , Bobkov V. , Cathey A. , Di Siena A. , Hoelzl M. , Messiaen A. , Myra J.R. , Suárez López G. , Tierens W. , Usoltceva M. , Wright J.C. , the ASDEX Upgrade Team  , the EUROfusion MST1 Team  
Published: November 2021

Abstract
This paper summarizes recent progress in modeling the interaction between ion cyclotron range of frequency (ICRF) waves and edge plasma with application to ASDEX Upgrade. The basic theories, the development of ICRF and edge plasma codes, the integrated modeling methods and some key results are reviewed. In particular, the following physical aspects are discussed: (1) ICRF power coupling; (2) slow wave propagation; (3) ICRF-rectified sheath; (4) ICRF-induced convection; (5) ICRF-edge turbulence interaction. Moreover, comprehensive integrated modeling strategies by including all necessary codes in one package and solving multiple physical issues self-consistently are discussed.
Hydrodynamics of weak integrability breaking
Authors: Bastianello Alvise , De Luca Andrea , Vasseur Romain 
Published: November 2021

Abstract
We review recent progress in understanding nearly integrable models within the framework of generalized hydrodynamics (GHD). Integrable systems have infinitely many conserved quantities and stable quasiparticle excitations: when integrability is broken, only a few residual conserved quantities survive, eventually leading to thermalization, chaotic dynamics and conventional hydrodynamics. In this review, we summarize recent efforts to take into account small integrability breaking terms, and describe the transition from GHD to standard hydrodynamics. We discuss the current state of the art, with emphasis on weakly inhomogeneous potentials, generalized Boltzmann equations and collision integrals, as well as bound-state recombination effects. We also identify important open questions for future works.
Analog pile-up circuit technique using a single capacitor for the readout of Skipper-CCD detectors
Authors: Sofo Haro M. , Chavez C. , Lipovetzky J. , Alcalde Bessia F. , Cancelo G. , Chierchie F. , Estrada J. , Fernandez Moroni G. , Stefanazzi L. , Tiffenberg J. , Uemura S. 
Published: November 2021

Abstract
With Skipper-CCD detectors it is possible to take multiple samples of the charge packet collected on each pixel. After averaging the samples, the noise can be extremely reduced allowing the exact counting of electrons per pixel. In this work we present an analog circuit that, with a minimum number of components, applies a double slope integration (DSI) and at the same time averages the multiple samples, producing at its output the pixel value with sub-electron noise. For this purpose, we introduce the technique of using the DSI integrator capacitor to add the skipper samples. An experimental verification using discrete components is presented, together with an analysis of its noise sources and limitations. After averaging 400 samples it was possible to reach a readout noise of 0.18 e-
rms/pix, comparable to other available readout systems. Due to its simplicity and significant reduction of the sampling requirements, this circuit technique is of particular interest in particle experiments and cameras with a high density of Skipper-CCDs.
The interplay between (electro)chemical and (chemo)mechanical effects in the cycling performance of thiophosphate-based solid-state batteries
Authors: Teo Jun Hao , Strauss Florian , Walther Felix , Ma Yuan , Payandeh Seyedhosein , Scherer Torsten , Bianchini Matteo , Janek Jürgen , Brezesinski Torsten 
Published: November 2021

Abstract
Solid-state batteries (SSBs) are a promising next step in electrochemical energy storage but are plagued by a number of problems. In this study, we demonstrate the recurring issue of mechanical degradation because of volume changes in layered Ni-rich oxide cathode materials in thiophosphate-based SSBs. Specifically, we explore superionic solid electrolytes (SEs) of different crystallinity, namely glassy 1.5Li2S-0.5P2S5-LiI and argyrodite Li6PS5Cl, with emphasis on how they affect the cyclability of slurry-cast cathodes with NCM622 (60% Ni) or NCM851005 (85% Ni). The application of a combination of ex situ and in situ analytical techniques helped to reveal the benefits of using a SE with a low Young’s modulus. Through a synergistic interplay of (electro)chemical and (chemo)mechanical effects, the glassy SE employed in this work was able to achieve robust and stable interfaces, enabling intimate contact with the cathode material while at the same time mitigating volume changes. Our results emphasize the importance of considering chemical, electrochemical, and mechanical properties to realize long-term cycling performance in high-loading SSBs.
Variant Library Annotation Tool (VaLiAnT): an oligonucleotide library design and annotation tool for saturation genome editing and other deep mutational scanning experiments
Authors: Barbon Luca , Offord Victoria , Radford Elizabeth J , Butler Adam P , Gerety Sebastian S , Adams David J , Tan Hong Kee , Waters Andrew J 
Published: November 2021

Abstract

Motivation
CRISPR/Cas9-based technology allows for the functional analysis of genetic variants at single nucleotide resolution whilst maintaining genomic context. This approach, known as saturation genome editing (SGE), a form of deep mutational scanning, systematically alters each position in a target region to explore its function. SGE experiments require the design and synthesis of oligonucleotide variant libraries which are introduced into the genome. This technology is applicable to diverse fields such as disease variant identification, drug development, structure–function studies, synthetic biology, evolutionary genetics and host–pathogen interactions. Here, we present the Variant Library Annotation Tool (VaLiAnT) which can be used to generate variant libraries from user-defined genomic coordinates and standard input files. The software can accommodate user-specified species, reference sequences and transcript annotations.

Results
Coordinates for a genomic range are provided by the user to retrieve a corresponding oligonucleotide reference sequence. A user-specified range within this sequence is then subject to systematic, nucleotide and/or amino acid saturating mutator functions. VaLiAnT provides a novel way to retrieve, mutate and annotate genomic sequences for oligonucleotide library generation. Specific features for SGE library generation can be employed. In addition, VaLiAnT is configurable, allowing for cDNA and prime editing saturation library generation, with other diverse applications possible.

Availability and implementation
VaLiAnT is a command line tool written in Python. Source code, testing data, example input and output files and executables are available (https://github.com/cancerit/VaLiAnT) in addition to a detailed user manual (https://github.com/cancerit/VaLiAnT/wiki). VaLiAnT is licensed under AGPLv3.

Supplementary information
Supplementary data are available at Bioinformatics online.
Biobox: a toolbox for biomolecular modelling
Authors: Rudden Lucas S P , Musson Samuel C , Benesch Justin L P , Degiacomi Matteo T 
Published: November 2021

Abstract

Motivation
The implementation of biomolecular modelling methods and analyses can be cumbersome, often carried out with in-house software reimplementing common tasks, and requiring the integration of diverse software libraries.

Results
We present Biobox, a Python-based toolbox facilitating the implementation of biomolecular modelling methods.

Availability and implementation
Biobox is freely available on https://github.com/degiacom/biobox, along with its API and interactive Jupyter notebook tutorials.
Faecal immunochemical test to triage patients with possible colorectal cancer symptoms: meta-analysis
Authors: Saw Kai Sheng , Liu Chen , Xu William , Varghese Chris , Parry Susan , Bissett Ian 
Published: November 2021

Abstract

Background
This review evaluated the utility of single quantitative faecal immunochemical test (FIT) as a triaging tool for patients with symptoms of possible colorectal cancer, the effect of symptoms on FIT accuracy, and the impact of triaging incorporating FIT on service provision.

Methods
Five databases were searched. Meta-analyses of the extracted FIT sensitivities and specificities for detection of colorectal cancer at reported f-Hb thresholds were performed. Secondary outcomes included sensitivity and specificity of FIT for advanced colorectal neoplasia and serious bowel disease. Subgroup analysis by FIT brand and symptoms was undertaken.

Results
Fifteen prospective cohort studies, including 28 832 symptomatic patients were included. At the most commonly reported f-Hb positivity threshold of ≥ 10 µg Hb/g faeces (n=13), the summary sensitivity was 88.7% (95% c.i. 85.2 to 91.4) and the specificity was 80.5% (95% c.i. 75.3 to 84.8) for colorectal cancer. At lower limits of detection of ≥ 2 µg Hb/g faeces, the summary sensitivity was 96.8% (95% c.i. 91.0 to 98.9) and the specificity was 65.6% (95% c.i. 59.0 to 71.6). At the upper f-Hb positivity thresholds of ≥ 100 µg Hb/g faeces and ≥ 150 µg Hb/g faeces, summary sensitivities were 68.1% (95% c.i. 59.2 to 75.9) and 66.3% (95% c.i. 52.2 to 78.0), with specificities of 93.4% (95% c.i. 91.3 to 95.1) and 95.1% (95% c.i. 93.6 to 96.3) respectively. FIT sensitivity was comparable between different assay brands. FIT sensitivity may be higher in patients reporting rectal bleeding.

Conclusion
Single quantitative FIT at lower f-Hb positivity thresholds can adequately exclude colorectal cancer in symptomatic patients and provides a data-based approach to prioritization of colonoscopy resources.
Time-dependent cortical plasticity during moderate-intensity continuous training versus high-intensity interval training in rats
Authors: Hugues Nicolas , Pin-Barre Caroline , Pellegrino Christophe , Rivera Claudio , Berton Eric , Laurin Jérôme 
Published: November 2021

Abstract
The temporal pattern of cortical plasticity induced by high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) is required to clarify their relative benefits to prevent neurological disorders. The purpose of this study is to define the time-dependent effects of work-matched HIIT and MICT on cortical plasticity, endurance, and sensorimotor performances over an 8-week training period in healthy rats. Adult healthy rats performed incremental exercise tests and sensorimotor tests before and at 2, 4, and 8 weeks of training. In parallel, cortical markers related to neurotrophic, angiogenic, and metabolic activities were assessed. Results indicate that HIIT induced an early and superior endurance improvement compared to MICT. We found significant enhancement of speed associated with lactate threshold (SLT) and maximal speed (Smax) in HIIT animals. MICT promoted an early increase in brain-derived neurotrophic factor and angiogenic/metabolic markers but showed less influence at 8 weeks. HIIT upregulated the insulin-like growth factor-1 (IGF-1) as well as neurotrophic, metabolic/angiogenic markers at 2 and 8 weeks and downregulated the neuronal K-Cl cotransporter KCC2 that regulates GABAA-mediated transmission. HIIT and MICT are effective in a time-dependent manner suggesting a complementary effect that might be useful in physical exercise guidelines for maintaining brain health.