bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heat-related cardiovascular morbidity and mortality in Switzerland: a clinical perspective
Authors: Schulte Florian , Röösli Martin , Ragettli Martina S. 
Published: September 2021

Summary

AIMS: Previous studies found increased cardiovascular mortality during hot days, while emergency hospital admissions were decreasing. We explored potential underlying reasons by analysing clinically similar cardiovascular disease groups taking into account primary, underlying and immediate causes of death.

METHODS AND RESULTS: We assessed associations of daytime maximum temperature in relation to cardiovascular deaths and emergency hospital admissions between 1998 and 2016 in Switzerland. We applied conditional quasi-Poisson models with non-linear distributed lag functions to estimate relative risks (RRs) of daily cardiovascular mortality and morbidity for temperature increases from the median (22 °C) to the 98th percentile (32 °C) of the warm season temperature distribution with 10 days of lag. Cardiovascular mortality (n = 163,856) increased for total cardiovascular disease (RR 1.13, 95% confidence interval [CI] 1.08–1.19) and the disease groups hypertension (1.18, 1.02–1.38), arrhythmia (1.29, 1.08–1.55), heart failure (1.22, 1.05–1.43) and stroke of unknown origin (1.20, 1.02–1.4). In contrast, emergency hospital admissions (n = 447,577) decreased for total cardiovascular disease (0.91, 0.88–0.94), hypertension (0.72, 0.64–0.81), heart failure (0.83, 0.76–0.9) and myocardial infarction (0.88, 0.82–0.95). Opposing heat effects were most pronounced for disease groups associated with diuretic and antihypertensive drug use, with the age group ≥75 years at highest risk.
CONCLUSIONS: Volume depletion and vasodilation from heat stress plausibly explain the risk reduction of heat-related emergency hospital admissions for hypertension and heart failure. Since primary cause of death mostly refers to the underlying chronic disease, the seemingly paradoxical heat-related mortality increase can plausibly be explained by an exacerbation of heat effects by antihypertensive and diuretic drugs. Clinical guidelines should consider recommending strict therapy monitoring of such medication during heatwaves, particularly in the elderly.
Script Analysis for Theatre
Authors: Knopf Robert 
Published: September 2021

Script Analysis for Theatre: Tools for Interpretation, Collaboration and Production provides theatre students and emerging theatre artists with the tools, skills and a shared language to analyze play scripts, communicate about them, and collaborate with others on stage productions. Based largely on concepts derived from Stanislavski’s system of acting and method acting, the book focuses on action - what characters do to each other in specific circumstances, times, and places - as the engine of every play. From this foundation, readers will learn to distinguish the big picture of a script, dissect and ’score’ smaller units and moment-to-moment action, and create individualized blueprints from which to collaborate on shaping the action in production from their perspectives as actors, directors, and designers.
Script Analysis for Theatre offers a practical approach to script analysis for theatre production and is grounded in case studies of a range of the most studied plays, including Sophocles’ Oedipus the King, Shakespeare’s Twelfth Night, Henrik Ibsen’s Hedda Gabler, Georg Büchner’s Woyzeck, Oscar Wilde’s The Importance of Being Earnest, Tennessee Williams’s A Streetcar Named Desire, and Paula Vogel’s How I Learned to Drive, among others. Readers will develop the real-life skills professional theatre artists use to design, rehearse, and produce plays.
The Laban Workbook for Actors
Authors: Bloom Katya , Adrian Barbara , Casciero Tom , Mizenko Jennifer , Porter Claire 
Published: September 2021

The Laban Workbook is a compendium of unique exercises inspired by the concepts and principles of movement theorist and artist, Rudolf Laban.
Written by five internationally recognized movement experts, this textbook is divided into single-authored chapters, each of which includes a short contextual essay followed by a series of insight-bearing exercises. These expert views, honed in the creation of individual approaches to training and coaching actors, provide a versatile range of theory and practice in the creative process of crafting theatre. Readers will learn:
Enhanced expressivity of body and voice;
Clearer storytelling, both physical and vocal, facilitating the embodiment of playwrights’ intentions;
Imaginative possibilities for exploring an existing play or for creating devised theatre.
Featuring many exercises exploring the application of Laban Movement Studies to text, character, scene work, and devised performances - as well as revealing the creative potential of the body itself - The Laban Workbook is ideal for actors, teachers, directors and choreographers.
Determinan Minat Kunjungan Wisata Berdasarkan Aksesibilitas, Fasilitas Pendukung Pariwisata & Norma Subyektif
Authors: Rumalatu Gilbert Alvin 
Published: September 2021

The purpose of this study was to examine and analyze the impact of accessibility, tourism support facilities and subjective norms on interest in tourist visits at Ora Beach and Banda Island. The population in this study were all tourists who visited 2 tourist sites in Central Maluku Regency, namely Ora Beach and Banda Island. Based on the character inherent in the population, the sampling method used is non-probability sampling through purposive sampling technique with a final sample size of 62 tourists. Testing research data begins with testing research instruments (validity and reliability tests), testing classical assumptions followed by testing multiple linear regression analysis.
The results showed that accessibility, tourism supporting facilities and subjective norms were proven to have a positive and significant effect on the interest in tourist visits on Ora Beach and Banda Island. This can be proven through the regression coefficient of accessibility, tourism supporting facilities and subjective norms which, if an increase, will be followed by an increase in interest in tourist visits. Thus it can be said that the increase in the value of accessibility, tourism support facilities and subjective norms will encourage an increase in interest in tourist visits on Ora Beach and Banda Island.
Rural Tourism, Agri Tourism; Sebuah Penelusuran Literature
Authors: Khaeril Khaeril , Mohungo Yolanda , - Laela 
Published: September 2021

Village are the smallest community entities that exist in a state structure. There are many problems faced, for example poverty, inadequate basic infrastructure, less skilled human resources, insufficient employment opportunities. Tourism village - Agri tourism is expected to be a solution to dealing with classic problems that exist in rural areas.
This article aims to identify research gaps in the field of study of tourism villages in a systematic search, identify reference authors in the field of Rural Tourism, agri-tourism., Identify the theories used in the Tourism Village article. The article implements a qualitative method with the Literature review method with the help of the Perish Publish Program to compile the data script and Vos Viewer is used to analyze the data. The results show that there is an opportunity to continue studying tourism villages, especially with regard to sustainable development, involvement of local communities and development / development of tourist villages, adopting ICT for tourism villages in order to improve performance and tourism visits, and alleviate poverty. Also obtained are several authors who become references in the study of tourist villages. There are also 13 theories used in studying tourism villages and agritourism, this shows that the tourism village as an object of study is still open to being in and is very dynamic in its development.
Rembrandt. The Painter Thinking
Authors: Wetering Ernst , Poelstra Wardy 
Published: September 2021

Even during the artist's lifetime, contemporary art lovers considered Rembrandt van Rijn (1606-1669) to be an exceptional artist. In this revelatory sequel to the acclaimed Rembrandt: The Painter at Work, renowned Rembrandt authority Ernst van de Wetering investigates the painter's considerations that determined the striking changes in his development from an early age onwards.
This gorgeously illustrated book explores how Rembrandt achieved mastery by systematic exploration of the 'foundations of the art of painting'. According to written sources from the seventeenth century, which were largely misinterpreted until now, these 'foundations' were considered essential at that time. From his first endeavours in painting, Rembrandt embarked on a journey past these foundations, thus becoming the 'pittore famoso', whom Count Cosimo the Medici visited at the end of his life. Rembrandt never stopped searching for solutions to the pictorial problems that confronted him; this led over time to radical changes that cannot simply be attributed to stylistic evolution or natural development.
In a quest as rigorous and novel as the artist's, Van de Wetering reveals how Rembrandt became the revolutionary painter that would continue to fascinate the art world. This ground breaking exploration reconstructs Rembrandt's theories and methods, shedding new light both on the artist's exceptional accomplishments and on the theory and practice of painting in the Dutch Golden Age.
The Meaning of Music
Authors: Samama Leo 
Published: September 2021

For virtually all of our lives, we are surrounded by music. From lullabies to radio to the praises sung in houses of worship, we encounter music at home and in the street, during work and in our leisure time, and not infrequently at birth and death. But what is music, and what does it mean to humans? How do we process it, and how do we create it?
Musician Leo Samama discusses these and many other questions while shaping a vibrant picture of music's importance in human lives both past and present. What is remarkable is that music is recognised almost universally as a type of language that we can use to wordlessly communicate. We can hardly shut ourselves off from music, and considering its primal role in our lives, it comes as no surprise that few would ever want to. Able to transverse borders and appeal to the most disparate of individuals, music is both a tool and a gift, and as Samama shows, a unifying thread running throughout the cultural history of mankind.
Exploration, Religion and Empire in the Sixteenth-century Ibero-Atlantic World
Authors: Nieto Olarte Mauricio 
Published: September 2021

The Iberian conquest of the Atlantic at the beginning of the sixteenth century had a notable impact on the formation of the new world order in which Christian Europe claimed control over most a considerable part of the planet. This was possible thanks to the confluence of different and inseparable factors: the development of new technical capacities and favorable geographical conditions in which to navigate the great oceans; the Christian mandate to extend the faith; the need for new trade routes; and an imperial organization aspiring to global dominance.
The author explores new methods for approaching old historiographical problems of the Renaissance—such as the discovery and conquest of America, the birth of modern science, and the problem of Eurocentrism—now in reference to actors and regions scarcely visible in the complex history of modern Europe: the ships, the wind, the navigators, their instruments, their gods, saints, and demons.
Ethnic Identity and the Archaeology of the aduentus Saxonum
Authors: Harland James M. 
Published: September 2021

For centuries, archaeologists have excavated the soils of Britain to uncover finds from the early medieval past. These finds have been used to reconstruct the alleged communities, migration patterns, and expressions of identity of coherent groups who can be regarded as ethnic 'Anglo-Saxons'. Even in the modern day, when social constructionism has been largely accepted by scholars, this paradigm still persists.
This book challenges the ethnic paradigm. As the first historiographical study of approaches to ethnic identity in modern 'Anglo-Saxon' archaeology, it reveals these approaches to be incompatible with current scholarly understandings of ethnicity. Drawing upon post-structuralist approaches to self and community, it highlights the empirical difficulties the archaeology of ethnicity in early medieval Britain faces, and proposes steps toward an alternative understanding of the role played by the communities of lowland Britain – both migrants from across the North Sea and those already present – in transforming the Roman world.
BƯỚC ĐẦU ĐÁNH GIÁ HIỆU QUẢ ĐIỀU TRỊ CỦA DECITABINE TRÊN NGƯỜI BỆNH LOẠN SINH TỦY TẠI BỆNH VIỆN TRUYỀN MÁU HUYẾT HỌC
Authors: Thị Hà Lê , Lê Quốc Vũ Trịnh , Thiện Ngôn Huỳnh , Phương Liên Nguyễn 
Published: September 2021

Mục tiêu: Đánh giá hiệu quả điều trị và độc tính của việc điều trị Decitabine trên người bệnh loạn sinh tủy (MDS). Đối tượng và phương pháp nghiên cứu: Mô tả hàng loạt ca, các người bệnh được chẩn đoán MDS, thỏa tiêu chuẩn nhận vào và được điều trị với Decitabine 20mg/m²/ ngày x 5 ngày, từ tháng 01/2019 đến tháng 7/2021 tại bệnh viện Truyền máu Huyết học (BV.TMHH). Đánh giá đáp ứng điều trị theo IWG 2006. Kết quả: 32 người bệnh (18 nam, 14 nữ) được phân loại theo WHO 2016, chiếm tỉ lệ cao nhất là nhóm MDS tăng tế bào non-2 (MDS-EB2) (56,2%) và nhóm nguy cơ rất cao theo IPSS-R (56,2%). Người bệnh được điều trị từ 1 đến 11 chu kỳ Decitabine với tỉ lệ đáp ứng toàn bộ (ORR: CR+PR) là 21,9%; trong đó đạt đáp ứng hoàn toàn (CR) là 12,5% và đạt đáp ứng một phần (PR) là 9,4%. Đáp ứng tủy xương hoàn toàn (mCR) là 25%. Nhóm người bệnh điều trị >4 chu kỳ có tỉ lệ đạt ORR, CR; thời gian sống còn toàn bộ(OS); sống không tiến triển bệnh (PFS); sống không tiến triển thành AML (AMLFS) cao hơn nhóm điều trị ≤4 chu kỳ (p lần lượt: 0,032; 0,009; 0,007; 0,01; 0,009). Tỉ lệ người bệnh độc lập truyền hồng cầu, tiểu cầu tăng theo chu kỳ, tại chu kỳ 6 cùng bằng 40%. Thời gian theo dõi trung vị là 7 tháng với trung vị của OS; PFS; AMLFS lần lượt là: 12,3; 7,9; 11,6 (với độ tin cậy 95%). Nhóm người bệnh đạt PR/CR có OS và AMLFS kéo dài hơn nhóm không đạt (p lần lượt: 0,004; 0,016). Biến chứng độ III-IV thường gặp trong quá trình điều trị là: nhiễm trùng 68,7%; giảm bạch cầu hạt 68,7%; giảm tiểu cầu 65,6%; thiếu máu 56,2%;. Tử vong do biến chứng điều trị là 18,7% (chủ yếu do biến chứng nhiễm trùng kết hợp giảm bạch cầu hạt nặng). Kết luận: Sử dụng Decitabine trong điều trị MDS cho thấy hiệu quả trong giảm nhu cầu truyền chế phẩm máu, giúp cải thiện huyết học, đồng thời giúp kéo dài thời gian OS, PFS, AMLFS cho người bệnh, đặc biệt ở nhóm người bệnh có đáp ứng điều trị.
Calibration and assessment of electrochemical low-cost sensors in remote alpine harsh environments
Authors: Dallo Federico , Zannoni Daniele , Gabrieli Jacopo , Cristofanelli Paolo , Calzolari Francescopiero , de Blasi Fabrizio , Spolaor Andrea , Battistel Dario , Lodi Rachele , Cairns Warren Raymond Lee , Fjæraa Ann Mari , Bonasoni Paolo , Barbante Carlo 
Published: September 2021

Abstract. This work presents results from an original open-source low-cost sensor (LCS) system developed to measure tropospheric O3 in a remote high altitude alpine site. Our study was conducted at the Col Margherita Observatory (2543 m above sea level), in the Italian Eastern Alps. The sensor system mounts three commercial low-cost O3/NO2 sensors that have been calibrated before field deployment against a laboratory standard (Thermo Scientific; 49i-PS), calibrated against the standard reference photometer no. 15 calibration scale of the World Meteorological Organization (WMO). Intra- and intercomparison between the sensors and a reference instrument (Thermo Scientific; 49c) have been conducted for 7 months from May to December 2018. The sensors required an individual calibration, both in laboratory and in the field. The sensor's dependence on the environmental meteorological variables has been considered and discussed. We showed that it is possible to reduce the bias of one LCS by using the average coefficient values of another LCS working in tandem, suggesting a way forward for the development of remote field calibration techniques. We showed that it is possible reconstruct the environmental ozone concentration during the loss of reference instrument data in situations caused by power outages. The evaluation of the analytical performances of this sensing system provides a limit of detection (LOD) <5 ppb (parts per billion), limit of quantification (LOQ) <17 ppb, linear dynamic range (LDR) up to 250 ppb,
intra-Pearson correlation coefficient (PCC) up to 0.96, inter-PCC >0.8, bias >3.5 ppb and ±8.5 at 95 % confidence. This first implementation of a LCS system in an alpine remote location demonstrated how to obtain valuable data from a low-cost instrument in a remote environment, opening new perspectives for the adoption of low-cost sensor networks in atmospheric sciences.
Exploring how groundwater buffers the influence of heatwaves on vegetation function during multi-year droughts
Authors: Mu Mengyuan , De Kauwe Martin G. , Ukkola Anna M. , Pitman Andy J. , Guo Weidong , Hobeichi Sanaa , Briggs Peter R. 
Published: September 2021

Abstract. The co-occurrence of droughts and heatwaves can have
significant impacts on many socioeconomic and environmental systems.
Groundwater has the potential to moderate the impact of droughts and
heatwaves by moistening the soil and enabling vegetation to maintain higher
evaporation, thereby cooling the canopy. We use the Community Atmosphere
Biosphere Land Exchange (CABLE) land surface model, coupled to a groundwater
scheme, to examine how groundwater influences ecosystems under conditions of
co-occurring droughts and heatwaves. We focus specifically on south-east
Australia for the period 2000–2019, when two significant droughts and
multiple extreme heatwave events occurred. We found groundwater plays an
important role in helping vegetation maintain transpiration, particularly in
the first 1–2 years of a multi-year drought. Groundwater impedes
gravity-driven drainage and moistens the root zone via capillary rise. These
mechanisms reduced forest canopy temperatures by up to 5 ∘C during
individual heatwaves, particularly where the water table depth is shallow.
The role of groundwater diminishes as the drought lengthens beyond 2 years
and soil water reserves are depleted. Further, the lack of deep roots or
stomatal closure caused by high vapour pressure deficit or high temperatures
can reduce the additional transpiration induced by groundwater. The capacity
of groundwater to moderate both water and heat stress on ecosystems during
simultaneous droughts and heatwaves is not represented in most global
climate models, suggesting that model projections may overestimate the risk of
these events in the future.
Práticas de escrita na universidade: vozes de autoria no gênero resenha
Authors: Batista-Santos Dalve Oliveira , Silva Dimas Henrique Pereira de Oliveira 
Published: September 2021

A pesquisa em questão teve por objetivo analisar a escrita dos alunos do curso de Letras de uma Universidade Pública do estado do Tocantins, a fim de examinar a forma como estes se assumem autores dos textos produzidos na disciplina de Morfologia do Português, no gênero textual resenha. Esse gênero está na ordem do argumentar (DOLZ; SCHNEUWLY, 2004), permitindo ao resenhista agir, tanto em descrição da obra resenhada, quanto em avaliação, ora em um extremo ora em outro. Dessa forma, a presente pesquisa apresenta-se situada no paradigma de pesquisa qualitativa, de natureza documental, com uma concepção transgressiva (PENNYCOOK, 2006) de Linguística Aplicada. Os resultados mostraram como os acadêmicos, citam e fazem referências aos textos por meio de elementos linguísticos-discursivos. Ainda, constatamos a funcionalidade dos adjetivos, advérbios e verbos de expressarem posicionamentos do resenhista em relação ao texto-base se dá em correspondência com os verbos selecionados na resenha analisada.
Palavras-chave: Interacionismo Sociodiscursivo; Novos Estudos do Letramento; Autoria.
Occurrence, Antimicrobial Susceptibility and Biofilm Production in Listeria ‎monocytogenes Isolated from Pork and other Meat Processing Items at Oko-‎Oba Abattoir, Lagos State, Nigeria‎
Authors: Aiyedun J. O. , Olatoye O. I. , Oludairo O. O. , Adesope A. O. , Ogundijo O. 
Published: September 2021

Unhygienic slaughtering practices are associated with meat contamination by pathogens including Listeria monocytogenes. This study investigated the occurrence, bacterial load, antimicrobial susceptibility and biofilm formation of L. monocytogenes in pork, slaughter facilities and water from Oko-Oba abattoir, Lagos State, Nigeria. A total of 216 samples; 146, 30, 20 and 20 from pork, water, table swabs and knife swabs respectively were collected for bacteriological analysis. Listeria selective media was used to isolate and characterise L. monocytogenes, antimicrobial susceptibility of the isolated bacteria was also determined. Biofilm production by the isolates for periods of 12, 24 and 36 hours were evaluated. Glucose, ethanol and crystal violet binding assay were used as nutrient, stressor and indicator respectively. The occurrence of L. monocytogenes in pork, water samples, table and knife swabs were 64.5%, 75%, 90% and 95% respectively, while overall prevalence was 73.3%. The mean load per gram were 3.78 ± 2.85, 4.27 ± 2.54, 5.60 ± 1.95 and 5.52 ± 1.41 (p ˂ 0.05) for pork, water table and knife swab samples, respectively. Fifty five percent of the isolates exhibited multidrug resistance (MDR) patterns to erythromycin (55%), tetracycline (55%), augmentin (85%), amoxicillin (90%), cotrimoxazole (95%), and cloxacillin (100%). The isolates produced biofilms at different concentrations of glucose and ethanol with the highest concentrations of biofilm produced at 36 hours. There were significant differences in mean biofilm values produced by the isolates. The occurrence of L. monocytogenes and the bacterial load in different samples are of economic and public health importance. Hygienic meat production from the abattoir could prevent contamination of pork by L. monocytogenes.
Haematological Profile of Naturally Infected Haemoparasite Positive and ‎Negative Japanese Quails (Coturnix coturnix japonica)
Authors: Jubril A. J. , Olushola G. , Adekola A. A. , Adekunle L. A. , Antia R. 
Published: September 2021

Commercial quail farming is economically viable and feasible because quails are resistant tovarious diseases. But despite this reported resistance, little is known about its resistance tohaemoparasites. This study evaluates the haematological changes and haemoparasiticinfection of commercially raised quails. Fifty-seven adult quails raised on deep litter wererandomly selected for blood sampling in this study. Two milliliters of blood was collectedaseptically for complete blood count while blood smears were used for the determination ofhaemoparasite morphological characteristics. Haemoproteus spp. Plasmodium gallinaceum, and Leucocytozoon spp. were identified in this study. 38 (67%) of the quails were positive forsingle or mixed infection, 29 (51%) were positive for single infection and 9(16%) for mixedinfection. There was a (P<0.05) decrease in PCV, Hb, and RBC counts, and an increase inTWBC and eosinophil count in birds with haemoparasite as compared to the uninfected birds.There was (P<0.05) increase in total white blood cell and heterophil count in the plasmodiumpositive birds. Also, total white blood cell, heterophil, lymphocyte and eosinophil count were(P<0.05) increased in the Leucocytozoon positive birds. This increase was also observed inbirds with mixed infection. The high incidence of haemoparasitic infection in apparentlyhealthy quail, with significant haematological indices deviated from normal, is consistentwith reports of the resistance of quail to various disease diseases which thus includeshaemoparasitic infection.