bluuebunny/crossref_metadata_2025_split huggingface dataset:
The iron and oxygen content of LMC Classical Cepheids and its implications for the extragalactic distance scale and Hubble constant
Authors: Romaniello Martino , Riess Adam , Mancino Sara , Anderson Richard I. , Freudling Wolfram , Kudritzki Rolf-Peter , Macrì Lucas , Mucciarelli Alessio , Yuan Wenlong 
Published: November 2021

Context. Classical Cepheids are primary distance indicators and a crucial stepping stone in determining the present-day value of the Hubble constant H0 to the precision and accuracy required to constrain apparent deviations from the ΛCDM Concordance Cosmological Model.
Aims. We measured the iron and oxygen abundances of a statistically significant sample of 89 Cepheids in the Large Magellanic Cloud (LMC), one of the anchors of the local distance scale, quadrupling the prior sample and including 68 of the 70 Cepheids used to constrain H0 by the SH0ES program. The goal is to constrain the extent to which the luminosity of Cepheids is influenced by their chemical composition, which is an important contributor to the uncertainty on the determination of the Hubble constant itself and a critical factor in the internal consistency of the distance ladder.
Methods. We derived stellar parameters and chemical abundances from a self-consistent spectroscopic analysis based on equivalent width of absorption lines.
Results. The iron distribution of Cepheids in the LMC can be very accurately described by a single Gaussian with a mean [Fe/H] = −0.409 ± 0.003 dex and σ = 0.076 ± 0.003 dex. We estimate a systematic uncertainty on the absolute mean values of 0.1 dex. The width of the distribution is fully compatible with the measurement error and supports the low dispersion of 0.069 mag seen in the near-infrared Hubble Space Telescope LMC period–luminosity relation. The uniformity of the abundance has the important consequence that the LMC Cepheids alone cannot provide any meaningful constraint on the dependence of the Cepheid period–luminosity relation on chemical composition at any wavelength. This revises a prior claim based on a small sample of 22 LMC Cepheids that there was little dependence (or uncertainty) between composition and near-infrared luminosity, a conclusion which would produce an apparent conflict between anchors of the distance ladder with different mean abundance. The chemical homogeneity of the LMC Cepheid population makes it an ideal environment in which to calibrate the metallicity dependence between the more metal-poor Small Magellanic Cloud and metal-rich Milky Way and NGC 4258.
Grenzen einer neurootologisch-psychosomatischen Tinnitus
Spezialambulanz
Authors: Schaaf Helmut , Kastellis Georg , Hesse Gerhard 
Published: November 2021

ZusammenfassungGrenzen einer neurootologisch-psychosomatischen Tinnitus Spezialambulanz Wenn
auch eine neurootologische psychosomatische Tinnitus Spezialambulanz nicht
weitergeholfen hat
Ziel Patienten mit einem Leiden an Tinnitus
fühlen sich oft in ihrer Not nicht ausreichend verstanden und
beklagen, dass ihnen ein Besuch beim Arzt oder Therapeuten nicht
weitergeholfen habe. Dies liegt auch an der Verknüpfung der
organischen Grundlagen für den Tinnitus mit zahlreichen psychischen
Faktoren, die an der Aufrechterhaltung des Leidens am Tinnitus beteiligt
sind. In einer spezialisierten Ambulanz sollten sowohl der neurootologische
als auch der psychosomatische Anteil angemessen aufgegriffen werden
können, so dass den Tinnitus- Patienten ein solcher Besuch
weiterhelfen sollte. Hier sollen die Größenordnung und
mögliche Gründe dafür, dass ein Besuch nicht
weitergeholfen hat, untersucht werden.
Material und
Methode Nachuntersucht wurden 295 von 699 einmalig ambulant gesehenen
Patienten, die mit dem Symptom Tinnitus eine Spezialambulanz aufsuchten.
Dabei wurden Hörbefunde erstellt sowie der Mini-Tinnitus-Fragebogen
(TF 12) nach Hiller und Goebel 1 zur
Symptombelastung und die deutschsprachige Version des Hospitality Anxiety
and Depression Score (HADS) 2 zur
Abschätzung der Angst- und der Depressionskomponente eingesetzt.
Frühestens 6 Monate später, durchschnittlich nach 32
Monaten, wurden die Patienten gebeten, einen ihnen zugeschickten Fragebogen,
u. a. mit der Frage: „Der Besuch hat mir nicht
weitergeholfen“, sowie erneut den Mini-TF (TF 12) und den HADS
auszufüllen. Ergebnisse: 42 Patienten (14%) gaben an, dass
ihnen der Besuch nicht weitergeholfen habe. Bei diesen zeigten sich
– trotz des erfolgten Counsellings – weder Verbesserungen im
TF12 noch im HADS. Sie fühlten sich deutlich weniger verstanden und
setzten eklatant weniger um als die Patienten, die angaben, dass ihnen der
Besuch geholfen habe. Als Hauptgründe dafür, dass der Besuch
nicht weitergeholfen hat, wurden das Beharren auf somatischen
Lösungen (40%) und die Nichtumsetzung von indizierten
psychotherapeutischen Maßnahmen vermutet (26%).

Schlussfolgerung Grundlage einer Tinnitus-Behandlung ist
ein neurootologisch fundiertes Counselling. Dennoch kann dies als nicht
weiterhelfend empfunden werden. Dies kann Gründe beim Patienten,
beim Behandler und in deren Interaktion
haben.
How Inclusive are the Local Economic Impacts of Social Protection in Uganda?
Authors: Kuss Maria Klara , Gassmann Franziska , Mugumya Firminus 
Published: November 2021

AbstractInclusive growth and development are essential for the sustainability of poverty reduction and growth. Social protection has been promoted as part of the inclusive growth and development agenda by emphasising the positive impacts of social transfers on people’s participation in economic processes. However, the focus on the positive economic impacts of social transfers has led to the neglect of concerns regarding inequality of opportunity. Taking the case of Uganda’s Senior Citizens Grant, this paper critically assesses how inclusive the impacts of social transfers are on economic processes. This is done by examining the extent to which local economic structures interplay with the impacts of the Grant. Based on a qualitative case study design, the analysis reveals that the scheme has unwittingly reinforced spatial patterns of economic exclusion and disadvantage. Recipients in remote areas are more likely to stay or fall back into poverty compared to people in integrated areas. For social transfers to contribute to inclusive growth and development for all, it will be vital to invest in complementary development interventions in economically disadvantaged areas.
A new force-measuring balance for large-scale model in hypersonic wind tunnel
Authors: Wang Qinchao , Li Shichao , Gao Hongli , Lv Jinzhou , Zhang Xiaoqing , Liu Weixiong , Liu Zihao 
Published: November 2021

There is a strong coupling effect between the body and propulsion system of the integrated hypersonic vehicle. The scaled-down model cannot reflect the laws of physics. Therefore, carrying out hypersonic aerodynamic tests using large-scale aircraft models is an urgent difficulty and the key link in the research of hypersonic aircraft. This Note presents a design scheme of large-scale and heavy-load three-component gauge strain balance. The balance innovatively uses the design of a “herringbone” force measuring element and a support plate to ensure the sensitivity of the main channel and solve the problem of serious coupling between channels. In order to solve the problem of insufficient stiffness caused by the large scale of the model, two convex plates are added to the contact surface between the model and the balance. Therefore, the difficulties encountered by large-scale aircraft models in a pulsed wind tunnel can be overcome effectively. The balance is verified by static calibration and wind tunnel test to meet the requirements. The results show that the balance meets the requirements of the aerodynamic load test of the large-scale and heavy-duty hypersonic vehicle model in a pulse combustion wind tunnel.
Lipofuscin causes atypical necroptosis through lysosomal membrane permeabilization
Authors: Pan Chendong , Banerjee Kalpita , Lehmann Guillermo L. , Almeida Dena , Hajjar Katherine A. , Benedicto Ignacio , Jiang Zhichun , Radu Roxana A. , Thompson David H. , Rodriguez-Boulan Enrique , Nociari Marcelo M. 
Published: November 2021

SignificanceRetinal lipofuscin causes retinal pigment epithelium cell death in Stargardt and potentially dry–Age-Related Macular Degeneration (AMD). The current dogma is that lipofuscin’s cytotoxicity results from the light-triggered decomposition of its lipid-bisretinoids leading to apoptosis. However, antiapoptotic antioxidants or light-blocking lenses are not effective to stop degeneration in Stargardt and most AMD patients. Here, we show that lipofuscin forms aggregates in lysosomes, which trigger lysosomal membrane permeabilization and subsequent atypical necroptosis. We provide evidence that necrosulfonamide, necrostatin-7, and arimoclomol can effectively control this lethal cascade.
De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes
Authors: Foray Anne-Perrine , Candon Sophie , Hildebrand Sara , Marquet Cindy , Valette Fabrice , Pecquet Coralie , Lemoine Sebastien , Langa-Vives Francina , Dumas Michael , Hu Peipei , Santamaria Pere , You Sylvaine , Lyon Stephen , Scott Lindsay , Bu Chun Hui , Wang Tao , Xu Darui , Moresco Eva Marie Y. , Scazzocchio Claudio , Bach Jean-François , Beutler Bruce , Chatenoud Lucienne 
Published: November 2021

Significance
The vast majority of autoimmune diseases are polygenic, and causal loci uncovered by genetic-mapping studies explain only a minority of the heritable contribution to trait variation. Multiple explanations for this missing heritability include rare meaningful variants, rare copy number variations or deletions, epistasis, epigenetics, disease heterogeneity, and rare or infrequent variants that segregate within individual families (even within monozygotic twins). Here we demonstrate that experimental models of spontaneous autoimmune diseases may be invaluable tools to map rare germline variants impacting disease susceptibility traits. We identified a variant of the dual-specificity phosphatase 10 encoding gene that accelerates disease in an autoimmune type 1 diabetes model, the nonobese diabetic mouse.
Nanometer-resolution in situ structure of the SARS-CoV-2 postfusion spike protein
Authors: Tai Linhua , Zhu Guoliang , Yang Minnan , Cao Lei , Xing Xiaorui , Yin Guoliang , Chan Chun , Qin Chengfeng , Rao Zihe , Wang Xiangxi , Sun Fei , Zhu Yun 
Published: November 2021

Significance
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a severe threat to public health and the global economy. Its spike protein is responsible for the membrane fusion and is thus a major target for vaccine and drug development. Our study presents the in situ structure of the spike protein in the postfusion state with higher resolution, giving further insights into the design of a viral entry inhibitor. Our observation of the oligomerization states of spikes on the viral membrane implies a possible mechanism of membrane fusion for viral infection.
The (minimal) persuasive advantage of political video over text
Authors: Wittenberg Chloe , Tappin Ben M. , Berinsky Adam J. , Rand David G. 
Published: November 2021

SignificanceVideo is an increasingly common source of political information. Although conventional wisdom suggests that video is much more persuasive than other communication modalities such as text, this assumption has seldom been tested in the political domain. Across two large-scale randomized experiments, we find clear evidence that “seeing is believing”: individuals are more likely to believe an event took place when shown information in video versus textual form. When it comes to persuasion, however, the advantage of video over text is markedly less pronounced, with only small effects on attitudes and behavioral intentions. Together, these results challenge popular narratives about the unparalleled persuasiveness of political video versus text.
Multimodal on-chip nanoscopy and quantitative phase imaging reveals the nanoscale morphology of liver sinusoidal endothelial cells
Authors: Butola Ankit , Coucheron David A. , Szafranska Karolina , Ahmad Azeem , Mao Hong , Tinguely Jean-Claude , McCourt Peter , Senthilkumaran Paramasivam , Mehta Dalip Singh , Agarwal Krishna , Ahluwalia Balpreet Singh 
Published: November 2021

Significance
We propose the integration of chip-based optical nanoscopy with high spatially sensitive quantitative phase microscopy to obtain three-dimensional (3D) morphology of liver sinusoidal endothelial cells (LSEC). LSEC contain large numbers of transcellular nanopores —“fenestrations”—in the plasma membrane, typically clustered in groups of 10 to 50 within areas called sieve plates. Determining the diameter and the height of fenestrated regions is an important indicator of a cell’s functionality, and these dimensions can be influenced by agents such as drugs. Our proposed multimodal microscope offers a solution for 3D nanoscale characterization of fenestration diameter and measurement of the optical thickness of the sieve plates.
An empirical resistance equation for the modelling of corona discharge in saline water
Authors: Stelmashuk Vitaliy , Schmidt Jiri 
Published: November 2021

Abstract
We present a study that was undertaken to calculate the resistance of low current corona discharge in saline water. A novel empirical model was obtained, based on several assumptions, which allowed us to determine the corona resistance using the measured current. This resistance could be then exploited to compute the power deposited to the corona as a function of time. The wall motion of a bubble freely oscillating in saline water was calculated using hydrodynamic equations and the calculated power function. A comparison of numerical simulations with experimental results showed that good agreement was achieved.
On Dark Gravitational Wave Standard Sirens as Cosmological Inference and Forecasting the Constraint on Hubble Constant using Binary Black Holes Detected by Deci-hertz Observatory
Authors: Chen Ju , Yan Changshuo , Lu Youjun , Zhao Yuetong , Ge Junqiang 
Published: November 2021

Abstract
Gravitational wave (GW) signals from compact binary coalescences can be used as standard sirens to constrain cosmological parameters if their redshift can be measured independently by electromagnetic signals. However, mergers of stellar binary black holes (BBHs) may not have electromagnetic counterparts and thus have no direct redshift measurements. These dark sirens may be still used to statistically constrain cosmological parameters by combining their GW measured luminosity distances and localization with deep redshift surveys of galaxies around it. We investigate this dark siren method to constrain cosmological parameters in detail by using mock BBH and galaxy samples. We find that the Hubble constant can be constrained well with an accuracy ≲1% with a few tens or more of BBH mergers at redshift up to 1 if GW observations can provide accurate estimates of their luminosity distance (with relative error of ≲0.01) and localization (≲0.1 deg2), though the constraint may be significantly biased if the luminosity distance and localization errors are larger. We also introduce a simple method to correct this bias and find it is valid when the luminosity distance and localization errors are modestly large. We further generate mock BBH samples, according to current constraints on BBH merger rate and the distributions of BBH properties, and find that the Deci-hertz Observatory (DO) in a half year observation period may detect about one hundred BBHs with signal-to-noise ratio ϱ ≳ 30, relative luminosity distance error ≲0.02 and localization error ≲0.01 deg2. By applying the dark standard siren method, we find that the Hubble constant can be constrained to the ∼0.1%–1% level using these DO BBHs, an accuracy comparable to the constraints obtained by using electromagnetic observations in the near future, thus it may provide insight into the Hubble tension. We also demonstrate that the constraint on the Hubble constant applying this dark siren method is robust and does not depend on the choice of the prior for the properties of BBH host galaxies.
Bioimpedance Spectroscopy as a potential technique to detect label-free PCR products
Authors: Ames-Lastra G , Sánchez V , Sacristán-Rock E , Gómez-López M , Pérez-Vielma N , Castillo-Salazar I A , Hernández-Nava A , González-Díaz C A 
Published: November 2021

Abstract
PCR is a molecular technique that multiplies DNA fragments in a logarithmical way. qPCR uses fluoroscopic dyes or probes to quantify amplicons but it is a complex and expensive technique that should be performed by highly trained personnel. PCR has been used in a wide variety of disciplines such as in food sciences, organ transplant, odontology, oncology and lately, as the standard diagnostic technique for COVID-19. Even when qPCR is a reliable and robust technique, it is hardly accessible for developing countries for its complex labelling procedures and expensive instrumentation, for that, it is of big relevance to search for simpler and cheaper alternative technologies for the detection and analysis of DNA. In this work, we explore the feasibility of using multifrequency bioimpedance measurements to detect label-free PCR products as a proof of principle for the future development of a gene biosensor on the basis of PCR and bioimpedance measurements.
Method of peripheral vein detection using Electrical Impedance Tomography
Authors: San-Pablo-Ju´arez M A , Orozco-Corona D M 
Published: November 2021

Abstract
The aim of the current contribution was to develop a method for locating arm veins in patients by using an electrical impedance tomography. Eight surface electrodes were placed on a simulated arm, separated at a fixed and equal distance from each other. The electrodes fed information about electrical impedance (conductivity) to EIDORS software. The three main phases (veins, muscle, and bone) each have different conductivity, which the device and software convert into a colour-coded tomograph displayed on a screen. The colour for blood on the image is previously set (in this case, red), revealing the location of the veins in the selected section of the arm. A sample run was made, successfully finding the correct location and size of the modelled vein, thus demonstrating the accurate operation of the device.
Effects of hectorite loading on tear properties and biodegradability of thermoplastic starch films
Authors: Ibrahim Ismail , Osman Azlin Fazlina , Adnan Sinar Arzuria , Sheng Lai Di , Haq Nazrul 
Published: November 2021

Abstract
Development of bio-based polymers can reduce human dependence on fossil fuel and move to a sustainable material resource. In this work, thermoplastics starch (TPS) films were produced by plasticization process, in which the crystalline structure of the starch granules was destroyed and reformed by water and glycerine through mechanical stirring and heating process. Hectorite was employed as filler to reinforce the TPS films. The hectorite was subjected to ultrasonication process for reducing the size and aggregation of particles. The ultrasonicated hectorite was added into the TPS solution to produce the TPS/hectorite bio-composite by film casting method. The TPS films with hectorite loading in the range of 1% to 5% were prepared. The morphology, tear strength and soil biodegradability of the TPS/hectorite bio-composite films were studied by altering the loading of hectorite incorporated into the TPS films. Results showed that the TPS/hectorite bio-composite films have higher tear strength compared to the pure TPS films. The tear strength of the bio-composite films slightly increased with hectorite content 1% and 2%. However, as the filler loading increased to 3%, there was a drastic increase of the tear strength. The maximum tear strength value was achieved by the TPS film when 4% hectorite filler was employed. The TPS/4% hectorite (ultrasonicated) has the lowest rate of soil biodegradation due to its lower moisture uptake and greatest interface interaction between starch and hectorite, inhibiting diffusion of bacteria into the films.
Simulation and optimization of steady-state heat transfer property measurement platform
Authors: Song Jiafang , Xie Jiawei , Wang jiao 
Published: November 2021

Abstract
This paper studies the measurement technology of heat transfer coefficient of building envelope, explores the main factors affecting the measurement of heat transfer coefficient, uses ANSYS Icepak software to simulate the steady-state heat transfer property measurement platform model, and establishes the virtual prototype of the product. The product design based on Icepak replaces the test on the physical prototype with the simulation on the virtual prototype, We should reduce or even cancel the manufacturing of physical prototype, shorten the R & D process, and cut R & D costs with the improvement of design quality. Through the comparison and analysis with the experimental data of the offline detection platform, the feasibility of using Icepak to simulate the equipment is proved. The software is used to simulate the ther-mal environment in the hot box. Through comparison and analysis, the most uniform upper wi-nd steady-state thermal environment scheme is found.
Research on Integrated Simulation Design Method of Performance and Reliability for Aerospace Electromechanical Products
Authors: Dai Yongde , Luan Jiahui , Zhu Xinggao 
Published: November 2021

Abstract
This paper proposes an integrated simulation method of the performance and reliability for aerospace electromechanical products, which can obtain the reliability parameters of the product through digital simulation, so as to guide the design of the product, taking into account the factors that affect the reliability in the design stage. This method is based on a multidisciplinary performance simulation model, comprehensively considers the failure mode and failure mechanism of the product. Through the method of DESIGN OF EXPERIMENT(DOE), the key design parameters and disturbance factors are combined and designed as input, the performance response surface model, the performance and reliability integrated simulation model are constructed in turn. Taking a typical aerospace electromechanical product solar wing drive mechanism as an example, the engineering application verification is carried out, and the response surface has a high matching degree with the sampling point, which can meet the engineering application.
Path planning of mobile robot based on particle swarm optimization algorithm
Authors: Yang Huimin , Jiang Lei , Wu Lijuan 
Published: November 2021

Abstract
Aiming at the premature convergence problem of particle swarm optimization (PSO) due to the loss of population diversity in the late stage of search, this paper improves the traditional PSO and proposes the elite mean deviation induction strategy, which improves the convergence speed and accuracy of PSO. The experimental results show that the convergence speed and accuracy of the improved PSO are improved. The effectiveness of the improved algorithm is proved.