bluuebunny/crossref_metadata_2025_split huggingface dataset:
Produksi Nasi Instan Berbasis Diversifikasi Pangan Lokal Ubi Ungu Sebagai Pangan Darurat Fungsional
Authors: Setiawan Erwin , Hidayatulloh Alpin , Widiastuti Tania 
Published: August 2021

Konsumsi beras di Indonesia masih sangat tinggi karena mayoritas penduduk Indonesia mengkonsumsi beras sebagai makanan pokok, hal tersebut membuat Indonesia harus mengimpor beras dari luar negeri. Selain itu Indonesia juga menjadi negara yang rawan terjadi bencana alam, keterbatasan bahan pokok dan peralatan memasak menjadi penyebab utama kurangnya pemenuhan gizi saat bencana alam. Pemanfaatan bahan baku umbi lokal sebagai produk diversifikasi menjadi beras instan. Penyusunan artikel ilmiah ini bersifat paparan, yaitu dengan menjelaskan Produksi Nasi Instan Berbasis Diversifikasi Pangan Lokal Umbi Ungu Sebagai Pangan Darurat Fungsional. Metode perumusan masalah dengan cara mengumpulkan beberapa masalah yang timbul dari latar belakang serta disusun secara sistematik. Penyusunan perumusan masalah menggunakan metode analisa dengan objek beras analog dari ubi ungu sebagai nasi instan dan mencoba mengaitkan dengan potensi dalam pengembangan produk pangan darurat yang bersifat fungsional. Pengumpulan data merujuk beberapa literatur berupa jurnal penelitian, prosiding, dan buku referensi. Penulis melakukan metode analisis dan pemecahan masalah dengan beberapaa tahapan yaitu memahami konsep permasalahan dengan menemukan kata kunci, merumuskan masalah yang akan dibahas, mengumpulkan data melalui studi literatur, melakukan diskusi lanjutan, mengurai rumusan masalah dengan menggunakan kata kunci, serta menemukan solusi dan menarik kesimpulan. Tujuan artikel ilmiah ini untuk memaparkan terobosan untuk pembuatan nasi instan berbahan dasar umbi lokal sebagai pemenuhan gizi. Metode analisa dengan objek beras analog dari ubi ungu sebagai nasi instan dan mencoba mengaitkan dengan potensi dalam pengembangan produk pangan darurat yang bersifat fungsional. Dari hasil pemaparan dapat disimpulkan bahwa ubi ungu bisa dijadikan sebagai bahan baku nasi instan serta memilki zat gizi yang baik untuk pemenuhan gizi pada manusia
The impact of the COVID-19 pandemic on the length of stay following total hip and knee arthroplasty in a high volume elective orthopaedic unit
Authors: Green Gemma , Abbott Sarah , Vyrides Yiannis , Afzal Irrum , Kader Deiary , Radha Sarkhell 
Published: August 2021

Aims Elective orthopaedic services have had to adapt to significant system-wide pressures since the emergence of COVID-19 in December 2019. Length of stay is often recognized as a key marker of quality of care in patients undergoing arthroplasty. Expeditious discharge is key in establishing early rehabilitation and in reducing infection risk, both procedure-related and from COVID-19. The primary aim was to determine the effects of the COVID-19 pandemic length of stay following hip and knee arthroplasty at a high-volume, elective orthopaedic centre. Methods A retrospective cohort study was performed. Patients undergoing primary or revision hip or knee arthroplasty over a six-month period, from 1 July to 31 December 2020, were compared to the same period in 2019 before the COVID-19 pandemic. Demographic data, American Society of Anesthesiologists (ASA) grade, wait to surgery, COVID-19 status, and length of hospital stay were recorded. Results A total of 1,311 patients underwent hip or knee arthroplasty in the six-month period following recommencement of elective services in 2020 compared to 1,527 patients the year before. Waiting time to surgery increased in post-COVID-19 group (137 days vs 78; p < 0.001). Length of stay also significantly increased (0.49 days; p < 0.001) despite no difference in age or ASA grade. There were no cases of postoperative COVID-19 infection. Conclusion Time to surgery and length of hospital stay were significantly higher following recommencement of elective orthopaedic services in the latter part of 2020 in comparison to a similar patient cohort from the year before. Longer waiting times may have contributed to the clinical and radiological deterioration of arthritis and general musculoskeletal conditioning, which may in turn have affected immediate postoperative rehabilitation and mobilization, as well as increasing hospital stay. Cite this article: Bone Jt Open 2021;2(8):655–660.
Polarization enhancement of linearly polarized light through foggy
environments at UV–NIR wavelengths
Authors: Zeng Xiangwei , Chen Xueye , Li Yahong , Xiangnan Qiao 
Published: August 2021

Wavelength is an essential factor affecting polarization propagation. We investigate the polarization persistence of linearly polarized light from ultraviolet to near-IR in foggy environments. Certain spectral bands, from ultraviolet to IR wavelengths that exhibit lower path loss, were initially selected. Using polarization-tracking Monte Carlo simulations for varying particle size, wavelength, refractive index and detection range, it is shown that linear polarization exhibits different persistence performance at different wavelengths in various foggy environments. For wet haze of 0.6 µm or 1 µm droplets, parallel polarization increases persistently as the wavelength increases, and has superior persistence in the near-IR region. For radiation fog of 5 µm or 7.5 µm droplets, parallel polarization shows superior persistence in the ultraviolet region. For advection fog of 15 µm or 45 µm droplets, parallel polarization shows a superior persistence in the ultraviolet region. It is therefore shown that changing the wavelength can improve linear polarization persistence in foggy environments.
Coming up short: Comparing venous blood, dried blood spots & saliva samples for measuring telomere length in health equity research
Authors: Geronimus Arline T. , Bound John , Mitchell Colter , Martinez-Cardoso Aresha , Evans Linnea , Hughes Landon , Schneper Lisa , Notterman Daniel A. 
Published: August 2021

Background
Telomere length (TL) in peripheral blood mononuclear cells (PBMC) from fresh venous blood is increasingly used to estimate molecular impacts of accumulated social adversity on population health. Sometimes, TL extracted from saliva or dried blood spots (DBS) are substituted as less invasive and more scalable specimen collection methods; yet, are they interchangeable with fresh blood? Studies find TL is correlated across tissues, but have not addressed the critical question for social epidemiological applications: Do different specimen types show the same association between TL and social constructs?

Methods
We integrate expertise in social epidemiology, molecular biology, and the statistical impact of measurement error on parameter estimates. Recruiting a diverse sample of 132 Metro-Detroit women, we measure TL for each woman from fresh blood PBMC, DBS, and saliva. Using regression methods, we estimate associations between social characteristics and TL, comparing estimates across specimen types for each woman.

Results
Associations between TL and social characteristics vary by specimen type collected from the same woman, sometimes qualitatively altering estimates of the magnitude or direction of a theorized relationship. Being Black is associated with shorter TL in PBMC, but longer TL in saliva or DBS. Education is positively associated with TL in fresh blood, but negatively associated with TL using DBS.

Conclusion
Findings raise concerns about the use of TL measures derived from different tissues in social epidemiological research. Investigators need to consider the possibility that associations between social variables and TL may be systematically related to specimen type, rather than be valid indicators of socially-patterned biopsychosocial processes.
“He who pays the piper calls the tune”: Researcher experiences of funder suppression of health behaviour intervention trial findings
Authors: McCrabb Sam , Mooney Kaitlin , Wolfenden Luke , Gonzalez Sharleen , Ditton Elizabeth , Yoong Serene , Kypri Kypros 
Published: August 2021

Background
Governments commonly fund research with specific applications in mind. Such mechanisms may facilitate ‘research translation’ but funders may employ strategies that can also undermine the integrity of both science and government. We estimated the prevalence and investigated correlates of funder efforts to suppress health behaviour intervention trial findings.

Methods
Our sampling frame was lead or corresponding authors of papers (published 2007–2017) included in a Cochrane review, reporting findings from trials of interventions to improve nutrition, physical activity, sexual health, smoking, and substance use. Suppression events were based on a previous survey of public health academics. Participants answered questions concerning seven suppression events in their efforts to report the trial, e.g., [I was…] “asked to suppress certain findings as they were viewed as being unfavourable.” We also examined the association between information on study funder, geographical location, targeted health behaviour, country democracy rating and age of publication with reported suppression.

Findings
We received responses from 104 authors (50%) of 208 eligible trials, from North America (34%), Europe (33%), Oceania (17%), and other countries (16%). Eighteen percent reported at least one of the seven suppression events relating to the trial in question. The most commonly reported suppression event was funder(s) expressing reluctance to publish because they considered the results ‘unfavourable’ (9% reported). We found no strong associations with the subject of research, funding source, democracy, region, or year of publication.

Conclusions
One in five researchers in this global sample reported being pressured to delay, alter, or not publish the findings of health behaviour intervention trials. Regulation of funder and university practices, establishing study registries, and compulsory disclosure of funding conditions in scientific journals, are needed to protect the integrity of public-good research.
Analysis of the coaptation role of the deltoid in reverse shoulder arthroplasty. A preliminary biomechanical study
Authors: Martinez Lucas , Machefert Margaux , Poirier Thomas , Matsoukis Jean , Billuart Fabien 
Published: August 2021

Background
Lateralization of the glenoid implant improves functional outcomes in Reverse Shoulder Arthroplasty. Lateralization does not appear to impact the Deltoid’s Moment Arm. Therefore, the stabilizing effect described in the literature would not be the result of an increase this moment arm. A static biomechanical model, derived from Magnetic Resonance Imaging, can be used to assess the coaptation effect of the Middle Deltoid. The objective of this study was to analyze the impact of increasing amounts of glenoid lateralization on the moment arm but also on its coaptation effect.

Methods
Eight patients (72.6 ± 6.5 years) operated for Reverse Shoulder Arthroplasty were included in the study. Three-dimensional models of each shoulder were created based on imaging taken at 6 months postoperative. A least square sphere representing the prosthetic implant was added to each 3D models. A static biomechanical model was then applied to different planar portions of the Middle Deltoid (from 3D models), first without lateralization and then with simulated lateralization of 6, 9 and 12mm. This static model enables to compute a Coaptation/Elevation Ratio and to measure the Deltoid’s Moment Arm. The inter- and intra-rater agreement of the 3D models was evaluated.

Results
One patient was excluded due to motion during imaging. The inter- and intra-rater agreement was over 0.99. The ratio increased starting at 6 mm of lateralization (p<0.05), compared to the initial position. The moment arm was not affected by lateralization (p<0.05), except in two slices starting at 9 mm (S1 p<0.05 and S2 p<0.05).

Conclusion
Our hypothesis that the Middle Deltoid’s coaptation role would be greater with glenosphere lateralization was confirmed. This trend was not found in the moment arm, which showed little sensitivity to lateralization. The stabilizing effect therefore appears to stem from the coaptation role of the Middle Deltoid.
The association between attachment pattern and depression severity in Thai depressed patients
Authors: Chinvararak Chotiman , Kirdchok Pantri , Lueboonthavatchai Peeraphon 
Published: August 2021

Objective
We aimed to study attachment patterns and their association with depression severity in Thai depressed patients.

Method
We conducted a descriptive study of depressed participants at King Chulalongkorn Memorial Hospital from November 2013 to April 2014. The Thai Short Version of Revised Experience of Close Relationships Questionnaire and the Beck Depression Inventory-II (BDI-II) were administered to all participants. We assessed BDI-II scores, classified by attachment patterns, using one-way analyses of variance. The associated factors and predictors of depression severity were analysed by chi-square and logistic regression analyses, respectively.

Results
A total of 180 participants (75% female; mean age = 45.2 ± 14.3 years) were recruited. Dismissing attachment was the most common pattern in Thai depressed patients (36.1%). Depressed patients with preoccupied attachment demonstrated the highest BDI-II scores. The best predictor of moderate to severe depression severity was preoccupied/fearful attachment (odds ratio = 3.68; 95% confidence interval = 2.05–7.30).

Conclusions
Anxious attachment was found to be associated with higher depression severity. Preoccupied/fearful attachment was the predictor of moderate to severe depression severity.
Differential prevalence of pathobionts and host gene polymorphisms in chronic inflammatory intestinal diseases: Crohn’s disease and intestinal tuberculosis
Authors: Khan Imteyaz Ahmad , Nayak Baibaswata , Markandey Manasvini , Bajaj Aditya , Verma Mahak , Kumar Sambudhha , Singh Mukesh Kumar , Kedia Saurabh , Ahuja Vineet 
Published: August 2021

Background and objectives
Crohn’s disease (CD) and Intestinal tuberculosis (ITB) are chronic inflammatory ulcero-constrictive intestinal diseases with similar phenotype. Although both are disease models of chronic inflammation and their clinical presentations, imaging, histological and endoscopic findings are very similar, yet their etiologies are diverse. Hence, we aimed to look at differences in the prevalence of pathobionts like adherent-invasive Escherichia coli (AIEC), Listeria monocytogenes, Campylobacter jejuni and Yersinia enterocolitica in CD and ITB as well as their associations with host-associated genetic polymorphisms in genes majorly involved in pathways of microbial handling and immune responses.

Methods
The study cohort included 142 subjects (69 patients with CD, 32 with ITB and 41 controls). RT- PCR amplification was used to detect the presence of AIEC, L. monocytogenes, C. jejuni, and Y. enterocolitica DNA in colonic mucosal biopsies. Additionally, we tested three SNPs in IRGM (rs13361189, rs10065172, and rs4958847), one SNP in ATG16L1 (rs2241880) and one SNP in TNFRSF1A (rs4149570) by real-time PCR with SYBR green from peripheral blood samples in this cohort.

Results
In patients with CD, AIEC was most frequently present (16/ 69, 23.19%) followed by L. monocytogenes (14/69, 20.29%), C. jejuni (9/69, 13.04%), and Y. enterocolitica (7/69, 10.14%). Among them, L. monocytogenes and Y. enterocolitica were significantly associated with CD (p = 0.02). In addition, we identified all the three SNPs in IRGM (rs13361189, rs10065172, and rs4958847), one SNP in ATG16L1 (rs2241880) and TNFRSF1A (rs4149570) with a significant difference in frequency in patients with CD compared with ITB and controls (p<0.05).

Conclusion
Higher prevalence of host gene polymorphisms, as well as the presence of pathobionts, was seen in the colonic mucosa of patients with CD as compared to ITB, although both are disease models of chronic inflammation.
The impact of the COVID-19 pandemic on microbial keratitis presentation patterns
Authors: Butt Gibran F. , Recchioni Alberto , Moussa George , Hodson James , Wallace Graham R. , Murray Philip I. , Rauz Saaeha 
Published: August 2021

Background
Microbial keratitis (MK) is the most common non-surgical ophthalmic emergency, and can rapidly progress, causing irreversible sight-loss. This study explored whether the COVID-19 (C19) national lockdown impacted upon the clinical presentation and outcomes of MK at a UK tertiary-care centre.

Methods
Medical records were retrospectively reviewed for all patients with presumed MK requiring corneal scrapes, presenting between 23rd March and 30th June in 2020 (Y2020), and the equivalent time windows in 2017, 2018 and 2019 (pre-C19).

Results
In total, 181 and 49 patients presented during the pre-C19 and Y2020 periods, respectively. In Y2020, concurrent ocular trauma (16.3% vs. 5.5%, p = 0.030) and immunosuppression use (12.2% vs 1.7%, p = 0.004) were more prevalent. Despite proportionately fewer ward admissions during the pandemic (8.2% vs 32.6%, p<0.001), no differences were observed in baseline demographics; presenting visual acuity (VA; median 0.6 vs 0.6 LogMAR, p = 0.785); ulcer area (4.0 vs 3.0mm2, p = 0.520); or final VA (0.30 vs 0.30 LogMAR, p = 0.990). Whilst the overall rates of culture positivity were similar in Y2020 and pre-C19 (49.0% vs. 54.7%, p = 0.520), there were differences in the cultures isolated, with a lower rate of poly-microbial cultures in Y2020 (8.3% vs. 31.3%, p = 0.022).

Conclusions
Patient characteristics, MK severity and final visual outcomes did not appear to be affected in the first UK lockdown, despite fewer patients being admitted for care. Concurrent trauma and systemic immunosuppression use were greater than in previous years. The difference in spectra of isolated organisms may relate to behavioural changes, such as increased hand hygiene.
ENTREVISTA COM O PROF. DR. NEWTON DUARTE
Authors: Duarte Rita de Cássia , Duarte Newton 
Published: August 2021

Newton Duarte possui graduação em Pedagogia pela Universidade Federal de São Carlos (1985), mestrado em Educação pela mesma instituição (1987), doutorado na Faculdade de Educação da UNICAMP (1992). É professor da UNESP, campus de Araraquara, desde 1988, onde obteve o título de Livre-Docente (1999) e ocupa o cargo de professor titular desde 2009. Foi pesquisador visitante no Instituto de Ontario para Estudos em Educação, da Universidade de Toronto (Ontario Institute for Studies in Education - OISE/UT) de 2003 a 2004; no Centro para Pensamento Político e Social (Centre for Social and Political Thought – CSPT) da Universidade de Sussex, Brighton, Inglaterra, de 2011 a 2012 e do Instituto de Humanidades (Institute for the Humanities), na Universidade Simon Fraser, Vancouver, Canadá, de 2019 a 2020. Suas pesquisas têm sido apoiadas pelo CNPq, pela CAPES e pela FAPESP. É líder do grupo de pesquisa “Estudos Marxistas em Educação”.
Newton Duarte possui graduação em Pedagogia pela Universidade Federal de São Carlos (1985), mestrado em Educação pela mesma instituição (1987), doutorado na Faculdade de Educação da UNICAMP (1992). É professor da UNESP, campus de Araraquara, desde 1988, onde obteve o título de Livre-Docente (1999) e ocupa o cargo de professor titular desde 2009. Foi pesquisador visitante no Instituto de Ontario para Estudos em Educação, da Universidade de Toronto (Ontario Institute for Studies in Education - OISE/UT) de 2003 a 2004; no Centro para Pensamento Político e Social (Centre for Social and Political Thought – CSPT) da Universidade de Sussex, Brighton, Inglaterra, de 2011 a 2012 e do Instituto de Humanidades (Institute for the Humanities), na Universidade Simon Fraser, Vancouver, Canadá, de 2019 a 2020. Suas pesquisas têm sido apoiadas pelo CNPq, pela CAPES e pela FAPESP. É líder do grupo de pesquisa “Estudos Marxistas em Educação”.
Autor de livros, capítulos de livros e artigos, publicados no Brasil e no exterior. Entre seus trabalhos destacam-se os livros: Os conteúdos escolares e a ressurreição dos mortos (2021, 2ª edição); A Individualidade Para Si (2013, 3ª ed), Vigotski e o Aprender a Aprender: crítica às apropriações neoliberais e pós-modernas da teoria vigotskiana (2011, 5ª edição); Sociedade do Conhecimento ou Sociedade das Ilusões? (2003); Crítica ao Fetichismo da Individualidade (2004); Critical Perspectives on Activity: Explorations across Education, Work and Everyday Life (2006) co-editada com Peter Sawchuk e Mohamed Elhammoumi; Arte, Conhecimento e Paixão na Formação Humana: Sete Ensaios de Pedagogia Histórico-Crítica (2010) em coautoria com Sandra Della Fonte; Conhecimento Escolar e Luta de Classes: a pedagogia histórico-crítica contra a barbárie (2021) em coautoria com Dermeval Saviani.
Molecular Profile of Trichophyton mentagrophytes and Microsporum canis based on PCR-RFLP of Internal Transcribed Spacer
Authors: Endrawati Dwi , Kusumaningtyas Eni 
Published: August 2021

<p><em>Trichophyton mentagrophytes</em> and <em>Microsporum canis</em> are dermatophytes fungi which commonly infect animal and human. Conventional and molecular methods were used for identification of the fungus. The region of internal transcribed spacer (ITS) has a high probability for fungal identification. PCR-RFLP was reported as a useful method to differentiate dermatophytes fungi. The objective of the study was<em> </em>to compare molecular profile of <em>T. mentagrophytes</em> and <em>M. canis</em> based on the result of ITS fragment digestion using Dde I, Hinf I and Mva I. The molds were isolated from skin scrapping of 18 animals which showed dermatophytosis lesion. The isolated molds were grown on agar plate for 14 days of incubation at 37<sup>o</sup>C and then identified based on macro and microscopic morphologies. Amplification of chitin synthase gene was used for confirmation and separation of dermatophytes from other fungi. ITS fragment was amplified and then digested using restriction enzymes Dde I, Hinf I and Mva I. The result showed that digestion products from ITS fragment of <em>T. mentagrophytes</em> and <em>M. canis </em>were different<em>.</em> The fragment 159 bp from Dde I, 374 bp from Hinf I and 89 bp from Mva I were present in <em>T. mentagrophytes</em> but absent in <em>M. canis</em>. Based on these results, specific RFLP profile of digestion ITS region by Dde I, Hinf I and Mva I can be used as a specific marker for species of dermatophytes fungi.</p>
Effect of Chicken Bone Extract Powder on Epididymal Sperm Quality of Male Wistar Rats
Authors: Buranaamnuay Kakanang , Kettawan A , Changsangfa C , Aiemongkot S 
Published: August 2021

Calcium is one of the minerals that are essential for male reproductive function. Calcium deficiency adversely affects spermatogenesis, normal sperm function and results in infertility. The sperm quality of rats fed a standard diet containing chicken bone extract powder (BEP) was assessed in the present study. Twenty male 8-week-old rats, Wistar strain, were randomized by weight into two groups of ten rats each and fed ad libitum a standard diet containing calcium carbonate (CaCO<sub>3</sub>, control) or chicken BEP; both were equivalent to 0.5% calcium. At the end of the 7-week consumption, the net body weight gains measured in control (101.33±21.81 g) and chicken BEP groups (100.74±26.80 g) were not significantly different (P&gt;0.05). The in vitro sperm quality in terms of concentration, motility, viability, resistance to hypotonic stress, acrosomal reaction ability and morphology was comparable between control and chicken BEP (all were P&gt;0.05). The results suggest that chicken BEP addition into feeds is an alternative calcium source that is as effective but less expensive as CaCO<sub>3,</sub> a commercial calcium (fortificant). At least, it has no detrimental effect on male reproductive function.