bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endovascular baroreflex amplification and the effect on sympathetic nerve activity in patients with resistant hypertension: A proof-of-principle study
Authors: van Kleef Monique E. A. M. , Heusser Karsten , Diedrich André , Oey P. Liam , Tank Jens , Jordan Jens , Blankestijn Peter J. , Williams Bryan , Spiering Wilko 
Published: November 2021

Background
First in human studies suggest that endovascular baroreflex amplification (EVBA) lowers blood pressure (BP). To explore potential mechanisms for BP reduction, this study examines the effects of EVBA on muscle sympathetic nerve activity (MSNA) and baroreceptor sensitivity (BRS).

Methods
In a single-center sub-study of the CALM-DIEM study (Controlling And Lowering blood pressure with the MobiusHD—Defining Efficacy Markers), 14 patients with resistant hypertension were treated with EVBA. Microneurography and non-invasive continuous BP measurements were performed at baseline and three months after MobiusHD implantation. The primary outcome was change in MSNA. Secondary outcomes were change in baroreflex sensitivity (BRS), cardiovascular responses to a sympathetic stimulus, BP, heart rate (HR) and heart rate variability (HRV).

Results
The primary endpoint was obtained in 10 of 14 patients enrolled in the sub-study. MSNA burst frequency and burst incidence decreased in 6 of 10 patients: mean change -4.1 bursts/min (95% confidence interval -12.2 to 4.0) and -3.8 bursts/100 heartbeats (-15.2 to 7.7). MSNA spike frequency and spike count decreased in 8 of 10 patients: mean change -2.8 spikes/sec (-7.3 to 1.8) and -3.0 spikes/heartbeat (-6.1 to 0.1). Change in MSNA and BP were not correlated. Office BP decreased by -14/-6 mmHg (-27 to -2/-15 to 3). We observed a trend towards decreased HR (-5 bpm, -10 to 1) and increased total power HRV (623 msec2, 78 to 1168). In contrast, BRS and cardiovascular responses remained unchanged after EVBA.

Conclusions
In this proof-of-principle study, EVBA did not significantly decrease MSNA in patients with resistant hypertension. EVBA did not impair baroreflex function.

Trial registration
Clinical trial registration at NCT02827032.
Prospective assessment of vacuum deliveries from midpelvic station in a tertiary care university hospital: Frequency, failure rates, labor characteristics and maternal and neonatal complications
Authors: Sugulle Meryam , Halldórsdóttir Erna , Kvile Janne , Berntzen Line Sissel Dahlgaard , Jacobsen Anne Flem 
Published: November 2021

Background
Midpelvic vacuum extractions are controversial due to reports of increased risk of maternal and perinatal morbidity and high failure rates. Prospective studies of attempted midpelvic vacuum outcomes are scarce. Our main aims were to assess frequency, failure rates, labor characteristics, maternal and neonatal complications of attempted midpelvic vacuum deliveries, and to compare labor characteristics and complications between successful and failed midpelvic vacuum deliveries.

Study design
Clinical data were obtained prospectively from all attempted vacuum deliveries (n = 891) over a one-year period with a total of 6903 births (overall cesarean section rate 18.2% (n = 1258). Student’s t-test, Mann-Whitney U-test or Chi-square test for group differences were used as appropriate. Odds ratios and 95% confidence intervals are given as indicated. The uni- and multivariable analysis were conducted both as a complete case analysis and with a multiple imputation approach. A p-value of <0.05 was considered statistically significant.

Results
Attempted vacuum extractions from midpelvic station constituted 36.7% (n = 319) of all attempted vacuum extractions (12.9% (n = 891) of all births). Of these 319 midpelvic vacuum extractions, 11.3% (n = 36) failed and final delivery mode was cesarean section in 86.1% (n = 31) and forceps in the remaining 13.9% (n = 5). Successful completion of midpelvic vacuum by 3 pulls or fewer was achieved in 67.1%. There were 3.9% third-degree and no fourth-degree perineal tears. Cup detachments were associated with a significantly increased failure rate (adjusted OR 6.13, 95% CI 2.41–15.56, p< 0.001).

Conclusion
In our study, attempted midpelvic vacuum deliveries had relatively low failure rate, the majority was successfully completed within three pulls and they proved safe to perform as reflected by a low rate of third-degree perineal tears. We provide data for nuanced counseling of women on vacuum extraction as a second stage delivery option in comparable obstetric management settings with relatively high vacuum delivery rates and low cesarean section rates.
Early Stimulation Influences the Development of a Child Between 0 and 3 Years of Age, in a Vulnerable Social Structure
Authors: Tomé José Manuel Salum 
Published: November 2021

The presence of Special Educational Needs (SEN) in students inserted in the school system has been a theme in which many areas of knowledge have tried to investigate. The psychological theory suggests that newborns begin their development starting from a similar basis, and that the different types of stimulation and the brain's ability to adapt to different episodes can be a determining factor in the development of skills and abilities. It is also considered that the family environment is the closest circle and with which the infants have the most contact in this period, therefore, the impact that the stimulation delivered by these people has on the adequate development of the cognitive, psychomotor and of a child's language, could be related to the presence of SEN and its subsequent consequences in the pedagogical and psychopedagogical areas when they enter the school system.

The present work aims to identify stimulation styles to favor the integral development of children up to three years of age.
The pathogenesis, epidemiology and biomarkers of susceptibility of pulmonary fibrosis in COVID-19 survivors
Authors: Vianello Andrea , Guarnieri Gabriella , Braccioni Fausto , Lococo Sara , Molena Beatrice , Cecchetto Antonella , Giraudo Chiara , Bertagna De Marchi Leonardo , Caminati Marco , Senna Gianenrico 
Published: November 2021

Abstract
Pulmonary fibrosis (PF), a pathological outcome of chronic and acute interstitial lung diseases associated to compromised wound healing, is a key component of the “post-acute COVID-19 syndrome” that may severely complicate patients’ clinical course. Although inconclusive, available data suggest that more than a third of hospitalized COVID-19 patients develop lung fibrotic abnormalities after their discharge from hospital. The pathogenesis of PF in patients recovering from a severe acute case of COVID-19 is complex, and several hypotheses have been formulated to explain its development. An analysis of the data that is presently available suggests that biomarkers of susceptibility could help to identify subjects with increased probability of developing PF and may represent a means to personalize the management of COVID-19’s long-term effects. Our review highlights the importance of both patient-related and disease-related contributing risk factors for PF in COVID-19 survivors and makes it definitely clear the possible use of acute phase and follow-up biomarkers for identifying the patients at greatest risk of developing this disease.
Recent progress in direct urea fuel cell
Authors: Putri Yulia Mariana Tesa Ayudia , Gunlazuardi Jarnuzi , Yulizar Yoki , Wibowo Rahmat , Einaga Yasuaki , Ivandini Tribidasari A. 
Published: November 2021

Abstract
Direct urea fuel cell (DUFC) has attracted many researchers’ attention due to the use of wastewater, for example urine, which contains urea for the fuel. The main factor to improve the electrochemical oxidation performance of urea and further enhance the performances of DUFC is the use of a good anode catalyst. Non-noble metal catalyst, such as nickel, is reported to have a good catalytic activity in alkaline medium towards urea electro-oxidation. Besides optimizing the anode catalyst, the use of supporting electrode which has a large surface area as well as the use of H2O2 as an oxidant to replace O2 could help to improve the performances. The recent progress in anode catalysts for DUFC is overviewed in this article. In addition, the advantages and disadvantages as well as the factors that could help to escalate the performance of DUFC are discussed together with the challenges and future perspectives.
Germanico –Germanikeia –Germanicus. Elementi per la rilettura di una festa efebica ateniese
Authors: Cecconi Niccolò 
Published: November 2021

RiassuntoIGermanikeiasono tra le più importanti feste efebiche ateniesi; tuttavia, l’anno della loro fondazione rimane incerto. Paul Graindor ipotizzò che la festa fosse stata istituita nel 18 d.C., in onore di Germanico, e officiata per lui fino alla metà del III secolo d.C. Questa ipotesi, sebbene universalmente accettata, non è basata su elementi probanti e deve essere pertanto rivalutata. Su questi presupposti, la ricerca prende in considerazione la documentazione, le caratteristiche deiGermanikeiaed i legami tra la celebrazione e gli esponenti della famiglia imperiale.
The effects of topic familiarity on information completeness, fluency, and target language quality of student interpreters in Chinese–English consecutive interpreting
Authors: Chen Hua , Wang Ying , Brown T. Pascal 
Published: November 2021

Abstract
This study investigated the effects of topic familiarity on interpreting quality of eighteen Master of Translation and Interpreting (MTI) student interpreters in Chinese–English consecutive interpreting (CI) at a university in China. Data were collected from two interpreting tasks in a 2-hour interpreting course over a four-week period. The interpreting quality was assessed by using three analytic rating scales (i.e., information completeness, fluency of delivery, and target language quality) and a holistic rating. Semi-structured interviews with the students were conducted to gain some in-depth perceptions of the effects of topic familiarity on interpreting quality. The results showed that topic familiarity had significant effects on information completeness, fluency of delivery, target language quality, and holistic scores of the interpreting tasks. It was also found that topic familiarity strongly correlated with information completeness, fluency of delivery, target language quality, and holistic scores. The findings of the study indicate that topic familiarity should be included and highlighted in Chinese–English consecutive interpreting in classroom contexts. The study provides effective guidance for interpreting teaching, training, and research.
The RP-HPLC method development and validation for simultaneous determination of oryzalin and ethofumesate pesticides in soil and water
Authors: Tandon Shishir , Pal Suman Lata 
Published: November 2021

Abstract
A sensitive and reliable method for simultaneous determination of oryzalin and ethofumesate residues in pantnagar soil and water was validated. The compounds were extracted by LLE with dichloromethane from water, and acetone:methanol mixture from soil followed by SPE cleanup. Detection and quantification was done by RP-HPLC using mobile phase methanol:water (70:30, v/v) at 280 nm. The developed method showed satisfactory validation results with linearity (0.99), relative standard deviations (1.55 and 1.73%), and limit of quantification (0.002 μg g−1 and 0.005 μg g−1) for ethofumesate and oryzalin, respectively. Recoveries ranged for oryzalin and ethofumesate from 79.80–90.52, 75.58–86.04% (soil) and 83.50–95.92, 82.28–94.60% (water), respectively. The method could be used for routine high-throughput detection and determination of these compounds.
The Values of Large (Particularly Large) Amounts of Income, Damage, Indebtedness for Economic Crimes
Authors: Lopashenko Natalia 
Published: November 2021

When formulating the objective side of economic crimes, the lawmakers often use such a result of deviant economic behavior as material damage, which could be large or particularly large; they also characterize the offence through the scale of actions or the amount of criminally acquired income (avoidance of losses) — its large (particularly large) amount. In general, this is a rational approach since the crimes are committed in the economic sphere, so their consequences and other features could and should be expressed through economic indicators. The problem for crimes under Chapter 22 of the Criminal Code of the Russian Federation consists in the fact that the number of legally defined variations in the understanding of large and particularly large amounts is constantly increasing and the difference between their minimum and the maximum levels is steadily growing. The article contains a detailed analysis of the contemporary condition of the problem of criteria for defining a large (particularly large) amount of income, damage, etc. for economic crimes. The author notes that there are 18 different variants for understanding a large amount of damage, income, or debt, and in 14 cases this large amount acts as the only indication of crime, i.e. the feature that makes it possible to criminalize the action. The same analysis is applied to the concept of a particularly large amount; Chapter 22 of the CC of the RF contains 12 variants of it. Such a wide range of values results in a number of negative consequences: the borders of criminalization for similar actions are defined differently, the limits of punishments included for them in the sanctions are established differently, different conditions for applying the norms of exemption from criminal liability for economic crimes are formed. The author analyses various ideas on changing approaches to defining the concepts of large (particularly large) amounts of income, damage, debt, and shows how these drawbacks in criminal legislation could be eliminated.
Bases para el diseño de un método pedagogico fundado en el discurso de los estudiantes
Authors: González Becerra Henry Ernesto 
Published: November 2021

The transition between secondary and higher education means for students to face different situations that question their capacity and learning dynamics. Skills such as argumentation, critical thinking and discursive coherence are aspects that students need to improve individually, but also institutions must work with regard to the teaching methods. A fundamental element for this purpose is the acquisition and extended use of the technical language of each disciplinary area. This document sets out the basis for the design of a pedagogical method based on the students' discourse. The public accounting program at the Antonio Nariño University, Duitama Campus, with 175 students in total, was the reference point for evaluation and analysis. Fieldwork included focus groups, participatory workshops, and evaluation questionnaires of the pedagogical method, autonomous learning and the students' environment. Finally, the effectiveness of the method was validated, contrasting the progress of the discourse, from prior knowledge, before entering higher education, to reach a more elaborate and complex cognitive, lexical and semantic structure. The method explains the acquisition and quality of discourse from four categories: cognitive progress, semantic unit, lexical unit and pedagogy. As a result, the implementation of strategies to internalize the source words, which are the technical and scientific concepts of a disciplinary area, allows to build a meaningful learning and to strengthen the oral and written discourse.
Problems of children who need special education and their families during the COVID-19 pandemic process
Authors: Gulkaya Sener , Sorakın Yasemin 
Published: November 2021

The COVID-19 pandemic process has been significant in all areas of our country, just like other countries of world. The changes in lifestyle that occurred with the pandemic process affected both children with special needs and their families. The aim of this research is to examine the effects of the pandemic on children with special needs and their families. The phenomenology model, one of the qualitative methods, was used as the research method in the study. The data obtained through the semi-structured interview form consisting of five questions developed by the researcher was analysed. The participants of the study comprised 29 parents, and data were obtained through telephone and online interview with 21 women and 8 men. As a result of the data, five main themes and related sub-themes were formed. Within the scope of the findings obtained in this study, the parents who constitute the participants of the study have observed an increase in the anxiety levels and aggressive behaviours of their children with special needs during the pandemic process, coupled with other findings as well.
Keywords: COVID-19, pandemic process, children with special needs, families
The role of concerted goal commitment mediation in improving lecturer research performance
Authors: Abdillah Maylane Boni , Rahardjo Tri Joko , Martono Martono , Prihatin Titi 
Published: November 2021

The purpose of this study was to analyse the mediating role of concerted goal commitment in improving a lecturer’s research performance. In this study, the research sample data used amounted to 365. The research method used simple random sampling. The instruments used were a questionnaire and structural equation modelling with Lisrel 8.80 as statistical analysis. Based on the results of this study, it is proven that leadership, academic culture, and academic policies can improve a lecturer’s research performance mediated by concerted goal commitment. The strength of the lecturer’s intention in commitment to shared goals is characterised by value creation, namely increasing the perception of goals, trust in the institution and the perception of the future so that it can strengthen the organisation or institution. This research can be extended to a state university to strengthen the hypothesis and the structural model that is built.
Keywords: academic culture, concerted goal commitment, leadership, lecturers, policy academic, and research performance
Childcare and housework during the first lockdown in Austria: Traditional division or new roles?
Authors: Berghammer Caroline 
Published: November 2021

Objective: This study analyses how much time mothers and fathers spent on childcare and housework during and after the first COVID-19 lockdown in Austria (starting in mid-March 2020) and how they distributed that time between themselves.
Background: Parents needed to reallocate care work between themselves as, on the one hand, kindergartens and schools closed for two months and, on the other hand, employment-related changes arose, e.g., working from home. The results are discussed in light of major theories that address the division of care work: the time availability approach and gender role theory.
Method: This study employs data from the Austrian Corona Panel Project 2020/21, a web-based survey using quota sampling, which started in the second week of the first lockdown (n=372 for respondents in couples with children below age 15). Altogether, seven waves contain information about time spent on childcare and housework; three were conducted during or right after the first lockdown (April and May 2020) and four between June 2020 and February 2021. Linear and logistic regression models were used.
Results: Within the whole study period, parents’ total workload (care work and employment) was highest during the first lockdown. The workload was greatest—an average of 15 hours on weekdays—among mothers with children below age six. While mothers shouldered more care work in most families, partners shared tasks equally in around one third of them. Care time depended on employment hours, especially for fathers. Yet, it was higher for mothers with the same level of employment as fathers.
Conclusion: The COVID-19-related employment changes led to a rise in arrangements that rarely existed before in Austria, e.g., fathers working part-time. Consequently, some fathers took on new roles, especially when they worked from home (mostly among the higher educated), were non-employed (mostly among the lower educated) or worked part-time. The paper concludes by discussing whether those experiences may permanently result in more egalitarian gender roles.
Risk-Controlled Wellbore Stability Criterion Based on a Machine-Learning-Assisted Finite-Element Model
Authors: AlBahrani Hussain , Morita Nobuo 
Published: November 2021

Summary
In certain drilling scenarios, the mud weight required to completely prevent wellbore enlargement can be impractically high. In such cases, what is known as risk-controlled wellbore stability criterion is introduced. This criterion allows for a certain and manageable level of wellbore enlargements to take place. Conventionally, the allowable level of wellbore enlargements in this type of model has always been based on the magnitude of the breakout angle. However, wellbore enlargements, as seen in caliper and image logs, can be highly irregular in terms of their distribution around the wellbore. This means that risk controlling wellbore stability through the breakout angle parameter can be insufficient. Instead, the total volume of cavings is introduced as the risk-control parameter. Unlike the breakout angle, the total volume of cavings can be coupled with a suitable hydraulics model to determine the threshold of manageable enlargement. The volume of cavings is determined using a machine-learning (ML)-assisted 3D elastoplastic finite-element model (FEM). The model implementation is first validated through experimental data. Next, a full data set from offset wells is used to populate and train the model. The trained model is then used to produce estimations of risk-controlled stability mud weights for different drilling scenarios. The model results are compared against those produced by conventional methods. Finally, both the FEM-ML model and the conventional method's results are compared against the drilling experience of the offset wells. The results illustrate how this methodology provides a more comprehensive and new solution to risk controlling wellbore stability.
Rapid Assembly of Colorless Antimicrobial And Anti-Odor Coatings From Polyphenols And Silver
Authors: Richardson Joseph J. , Liao Wenting , Li Jincai , Cheng Bohan , Wang Chenyu , Maruyama Taku , Tardy Blaise L. , Guo Junling , Zhao Lingyuan , An Wanping , Ejima Hirotaka 
Published: November 2021

Abstract
The development of antimicrobial fabrics and textiles that can sustainably inhibit a broad spectrum of microbes is crucial for protecting against pathogens in various environments. However, engineering antimicrobial textiles is challenging due to issues with discoloration and inhibited breathability, the use of harmful or harsh reagents and synthesis conditions, and complex and/or time-consuming processing. Herein, we develop a facile and rapid approach to deposit antimicrobial coatings using universally adherent plant polyphenols and antimicrobial silver ions. Importantly, the coatings are colorless, thin (<10 nm), rapidly assembled (<20 min), and can be deposited via immersion or spraying. We demonstrate that these metal-phenolic coatings on textiles can inhibit lipid-enveloped viruses over one thousand times more efficiently than coatings composed of other metal ions, while maintaining their efficacy even after 10 washes. Moreover, the coatings also inhibit Gram positive and negative bacteria, and fungi, and can prevent odors on clothes for at least 10 washes. Collectively, the ease of synthesis, use of simple and safe precursors, and amenability to at-home and industrial application suggests that the coatings will find practical application in various settings.