bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antiproliferatif Ekstrak Metanol Daun Dianella nemorosa Lam. (Liliaceae) terhadap Sel Kanker MKN45 dengan Menggunakan Metode WST-1
Authors: Karim Aditya K. , Sismindari Sismindari 
Published: July 2021

Dianella nemorosaÂ Lam. was known containing alkaloids, terpenoid, phenolic compouds and tanin. Antiproliferative effect of D. nemorosaÂ leaves methanol exctract, which demonstrated to have an in vitro cytotoxic effect on cancer cell line. The aim of research was examined the effect antiproliferative methanol extract of D. nemorosaÂ leaves against MKN45 (gastric cancer) cell line. Leaves powder extracted using methanol. Antiproliferative effect was determined by Cell Proliferation Reagents WST-1 ((2-(4-iodophenyl)-3-(4-nitro-phenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium monosodium salt). Test for 1h, 2h, and 4h after incubated for 72h was done. The result of this research showed that methanol exctract from D. nemorosaÂ possessed remarkable no had antiproliferative activity against MKN45 cell line. The result indicated methanol extract of D. nemorosaÂ leaves selective inhibitory effect or antiproliferative againstÂ cell line.Â Key words:Â Dianella nemorosa, Antiproliferative, MKN 45, and WST-1
Evaluasi Penggunaan Obat Antimalaria di Rumah Sakit Umum Daerah (RSUD) Abepura, Jayapura
Authors: Natalia Deshinta S. , Gunawan Elsye , Pratiwi Rani D. 
Published: July 2021

Evaluation of drug use is a quality assurance process that is carried out continuously, organizational structured and recognized to ensure that the drug is used appropriately and effectively. Until recently, Jayapura city is still as a malarial endemic area. In 2012, the number of malaria cases are malarial tertiana 8.535 (39%) cases, malarial tropical 12.256 (57%), malarial mix (tertiana+tropical) 612 (2,84%) and malarial quartana 73 (0,33%). The highest percentage of malarial cases in the Jayapura city is caused by Plasmodium falciparum. The aims of this study are to evaluate the drug use and the dose accuracy of antimalarial drugs in the General Hospital of Abepura from July to December 2014. This is a descriptive study conducted by a retrospective review of medical records of patients. The results of the study concluded that the highest incidence rates occurred in the male (59.04%) and lowest in women (40.96%), 15-25 years of age (57.8%), 26-35 years of age (27.7%) and Â 36-45 years of age (14.5%). The dose accuracy for antimalarial drugs (100%) indicated that antimalarial drugs used are Primaquine, Artesunate injection and Dihydroartemisin + piperaquine (DHP) or Darplex.Â Key words: Abepura hospital, antimalarial drug, Jayapura, malaria
Karakterisasi Mikrobia Rizosfer asal Tanaman Ginseng Jawa (Talinum triangulare) berdasarkan Gen Ribosomal 16S rRNA dan 18S rRNA
Authors: Ali Alimuddin , Rante Herlina 
Published: July 2021

The rhizosphere is a biologically active zone of the soil around plant roots that contains soil-borne microbes including bacteria and fungi. Â The microbes wereÂ isolated from rhizosphere soil roots of Java ginseng. The population of microbes was estimated by plate count method.Â The isolates were identified based on a great variety of morphological, and cultural characteristics.Â The total of rhizosphere soil microbe population were Â 20.91(106Â cfu.gâˆ’1soils) and showed that 12 isolates of bacteria, 15 isolates of actinomycetes, and 10 isolates of fungi which were found in all of soil samples. The molecularÂ analysis of theÂ ribosomalÂ genesÂ showedÂ that theÂ bacterialÂ isolate, actinomycetes and fungi were closely related to of Staphylococcus sp. DGM Â (JF923460), Streptomyces avidinii (EU593640) and fungi Aspergillus niger (HQ379853),Â respectively.Â Key words:Â rhizosphere, Java ginseng, 16S rRNA gene, 18S rRNA gene
Pengaruh Pemberian Etanol Peroral terhadap Berat Testis Tikus Putih (Rattus norvegicus Strain Wistar)
Authors: Oktavian Antonius , Elieser Elieser , Rahayu Agnes S. , Iswanto Dais 
Published: July 2021

Alcohol (ethanol) has long been used as liquor. In some areas in Indonesia, the use of ethanol is an insaperable part of family rites and traditional festivities. Â However, due to its serious consequences, alcoholism becomes a chronic social problem. Ethanol effects the metabolism in body organs and tissues, including male reproductive organ. The objective of this study was to prove that ethanol comsumption may reduce the weight of testis. This study used Posttest Only Group Design with experimental animals of 30 male rats (Wistar strain Rattus norvegicus) that were subjected in five types of treatment, i.e,(1) feeding with aquades 2ml/day as control group (2) feeding with 10% 1 gr/Kg/day of ethanol, (3) feeding with 10% 3gr/Kg/day of ethanol, (4) feeding with 30% 1 gr/Kg/day of ethanol and (5) feeding with 30% 3 gr/Kg/day of ethanol. Treatment was given daily for 45 days. At the end of the study, on the day 46th, the rats was sacrified for examination. Sample of testis were taken for weight examination. Â Data were analysed using Anova and when the difference was found, the analysis was followed with Least significant Difference at the level of significance of 95%. The result of this study showed that ethanol reduced the weight of testis compared to control. The results of Anova Â test revealed that higher dosage and concentrations of ethanol resulted in significantly different decrease of the testisâ€™s weight (p<0,05) compared to other dosage and other concetration. In conclusion, ethanol has effect in the reduction of the weight of the testis.Key words: ethanol, male reproduction, Rattus norvegicus, weightÂ of testis.
Kualitas Protein Ulat Sagu (Rhynchophorus bilineatus)
Authors: Purnamasari Vita 
Published: July 2021

Protein merupakan salah satu makronutrien penting bagi tubuh. Fungsinya sebagai zat pembangun dan memelihara sel-sel dan jaringan tubuh, menyebabkan kekurangan protein akan berakibat serius bagi kesehatan. Salah satu alternatif pemenuhan kebutuhan protein adalah dengan pemanfaatan bahan pangan lokal. Ulat sagu (Rhynchophorus papuanus) telah lama dikonsumsi oleh masyarakat asli Papua dan Maluku sebagai pelengkap (lauk) bubur sagu (papeda) dan diketahui dari kandungan zat gizinya dapat berperan sebagai sumber protein. Penelitian ini bertujuan mengetahui kualitas protein ulat sagu (Rhynchophorus papuanus). Ulat sagu dikembangbiakkan pada media batang sagu dengan tiga varietas sagu masing-masing adalah Debet Embyam, Kutu blup, dan Kutu MamakutuÂ (berdasarkanÂ pengetahuan indigineus etnikÂ Moy). Dilakukan analisis kimiawi untuk mengetahui kadar protein, lemak, air, dan abu. Sedangkan kualitas protein ulat sagu ditentukan dengan penentuan NPR (net protein ratio) dan penentuan nilai kimia asam amino. Hasil penelitian menunjukkan bahwa ulat sagu mengadung protein dengan kualitas cukup baik, yang diperlihatkan dengan nilai kimia asam amino ulat sagu, masing-masing yang dikembangbiakkan pada Debet Embyam = 97,54%; Kutu blupÂ = 80,77%; dan Kutu MamakutuÂ = 77,53% dengan asam amino pembatas metionin. Sedangkan nilai NPRnya masing-masing 3,31; 3,16; dan 3,17. Tidak ada perbedaan yang signifikan terhadap nilai NPR ketiga perlakuan tersebut.Key words: Kualitas protein, ulat sagu, Maribu, Jayapura.
Analisa Vegetasi Jenis Pohon pada Kawasan Hutan di Kampung Tablanusu Distrik Depapre Kabupaten Jayapura
Authors: Tanjung Rosye H.R. , Sufaati Supeni , Runggeari Lucia 
Published: July 2021

Tropical rain forest of Papua is very diverse in its floristic composition. Increasing human population cause the loss of forest for farming, urban areas or other human activities which cause deforestation. Â The objective of this study was to obtain Â the description of composition and structure as well as ecological value of Â forest area at Tablanusu Village, District of Depapre. Study was carried out from January â€“ June 2009. Quadrat plot (50 m x 20 m) were placed at Â 30 m a.s. l and 200 m a.s.l. . Index of Shannon-Wieners was used to determine the level of species diversity and Index of Similarity to indicate degree Â of similarity of composition between two different altitudes. Results of the study revealed that Â at 30 m a.s.l occupied by Â Â 25 species Â that grouped into 18 families of trees Â (Ã¸ > 10 cm) Â with total 146 trees., sapling (Ã¸ 2-10 cm) was Â consisted of 26 species Â of 15 families Â and 74 Â individuals. While Â at 200 m asl, there were 18 species of tress Â Â (Ã¸ > 10 cm) which grouped into 13 families with 93 individuals, 23 Â species of sapling (Ã¸ 2-10 cm) Â that grouped into 20 families with total Â number of individu was 82. The value of Similarity indices of theÂ tree at 30 m asl and 200 m asl Â was 0%, on the other hand for sapling its value showed 12,24 %. It means Â that there was a differences in Â the species composition on both areas. Furthermore, the Â species wich has highest Important value at 30 m asl was Â Cocos nucifera L.Â (63,84 %) for trees and Kleinhovia hospitaÂ L. (37,61 %) for sapling. Â While Â at 200 m asl, this highest value for trees was Â found in Instia bijugaÂ OK. (81,67 %), and Mastixiodendron pachyclados K.Sch (41,31 %) for sapling. Eventhough the regeneration procees in those forest was slow, but it has high ecological value, for example as water suply, preventing erotion, habitat of fauna and maintaining the microclimate.Â Â Keywords : analysis of forest vegetation, tree species, Tablanusu Â village, Depapre.
Variasi Foramen Mentale pada Tulang Mandibula Tengkorak Manusia Koleksi Laboratorium Anatomi Fakultas Kedokteran Universitas Cenderawasih
Authors: Oktavian Oktavianus , Elieser Elieser , Anike Anike , Iswanto Dais 
Published: July 2021

Knowledge of the position of the mental foramen is important both when administering regional anaesthesia,performing periapical surgery and dental implant surgery and endodontic treatments in the mandible.Â This study was to investigate the variation of the mental foramen in human skull. The study sample included eleven skulls taken in Anatomy Laboratory, Faculty of Medicine, Cenderawasih University. The mental foramen was symetrical in 100% of skulls. The most common size of foramen is 2.6 mm (46%) and the most common position of the mental foramen was between the first premolar and the second premolar (64%).Key words: Â mental foramen, variation , mandible, human skull
Toksisitas Isolat Lokal Bacillus thuringiensis (H-14) serta Lama Efektivitasnya di dalam Air terhadap Larva Nyamuk Anopheles farauti Laveran
Authors: Lantang Daniel 
Published: July 2021

The research of toxicity local isolate Bacillus thurigiensis (H-14) and 18 codeword isolate along the efectivity on the water concerning to the Anopheles. Â The research aim to acquainted about the toxicity of B. thuringiensis isolate H-14 local and 18 codeword isolate along of the toxicity on the water concerning to the Anopheles. The methode is laboratory experiment wich used complete randome, analysis the data to wich BNJ test and Î±..05. The result shows Â that isolate of local B. huringiensis H-14 Anopheles farauti Laveran Â B.thurngiensis H-14 Â Â 0.06 ml concentrate, 0.08 ml Â concentrate and 0.1 of effective of the A.farauti death until 6 day, and concentrate 0.1 ml effective Â show the Anopheles Â death until 7 day. Analysis varians shows the different act control concentrate Â in the other side, the act of concentrate isnt different significant.Â Â Key words: Toxic, Bacillus thuringiensis, Anopheles farauti Laveran.Â
Inveksi Human Papilloma Virus (HPV) dan Pencegahannya pada Remaja dan Dewasa Muda
Authors: Rahayu Agnes S. 
Published: July 2021

Human papillomavirus (HPV) is a significant source of morbidity and mortality worldwide. The primary risk factors for aquiring HPV are generally associated with sexual activity. Â Evidence suggest that condoms provide some protection against infection and disease progression, but any genital contact is sufficient for HPV transmission. Â Having more than one sexual partner often result in HPV infection. Â All sexually active adolescents are at high risk for aquiring HPV. Â Persistent infection with high-risk HPV types (e.g HPV 16 or 18) is considered necessary for the development cervical cancer. Â Most infection are asymptomatic and are efficiently cleared by he immune system. Â The lesions that caused by HPV can regress in adolescent and young adult women. Â A small percentage of adolescents will develop precancerous lesions that may progress to invasive cervical cancer. Â Adolescents should be given appropriate education about HPV and the dangers associated with infection. Â Vaccination for HPV infection should be given for presexually active children and adolescents.Key words: human papilloma virus, adolescent, cervical cancer, vaccination.Â
Pengetahuan Konservasi Tradisional Burung Endemik pada Masyarakat Kampung Soaib di Distrik Kemtuk, Kabupaten Jayapura
Authors: Beno Matias , Ohee Henderite L. 
Published: July 2021

This study was to investigate the endemic birds, local knowledge and the conservation efforts on the bird species. The study was conducted in the period from February 2007 to May 2008. Methods used including observation, interviews, documentation, description and literature review. The results showed that there were 11 spesies of endemic birds occured in Soaib village: Cassowary (Casuarius unappendiculatus), Yellow-crested Cockatoo (Cacatua galerita), two species of Megapodes; (Aypepodius arfakianus) and (Megapodius freycinet), Papuan Hornbill (Rhyticeros plicatus), Victoria Crowned-pigeon (Goura victoria), Palm Cockatoo (Prombosciger atterimus), Parrot (Psittrichas fulgidus), Papuan crow (Cracticus cassicus) Bird of Paradise (ParadiseaeÂ sp). Local people determined the forest in three different types; primary forest, buffer zone between primary and secondary forest and secondary forest. Primary forest was being the habitat for 11 endemic birds. These birds were hunted by local people for meat consumption and cultural purposes excepted the Papuan hornbill (Rhyticeros plicatus) and Papuan crow (Cracticus cassicus). Bird of Paradise (ParadiseaeÂ sp), and yellow-crested Cockatoo (Cacatua galerita) were captured to be sold in the market. This was happened because of lack information and education about the role of the birds in forest ecosystem.Â Key words:Â Traditional conservation, endemic birds, SoaibÂ village, JayapuraÂ
Potensi Vegetasi Non Kayu yang dimanfaatkan oleh Masyarakat di Distrik Unurum Guay, Kabupaten Jayapura
Authors: Kawengian Lani , Rumahorbo Basa 
Published: July 2021

The study on the potensial of Non Timber Forest Product (NTFP) used by people in District Unurum Guay, Jayapura was done in January to April 2007 using survey methods. The result showed that there were 85 species of plant consisted of 32 families. Some of them, used as food source (28,23%), medicinal plants (29,41%), furniture and buiding material (22,35%), as tools for ritual ceremony and traditional belief (17,65%), ornamental plant (16,47%) and traditional weapon and other (20%). The processy of the plant were varies, depended on their utilities, for example as food source, it can boiled, fried, grilled, cooked traditional or freshly eaten.Â Key words: NTFP, Unurum Guay, Jayapura.
Upaya Pemanfaatan Ekstrak Biji Keben Barringtonia asiatica (L.) Kurz terhadap Kematian Kutu Tempurung Hijau Coccus viridis pada Tanaman Kopi Coffea sp
Authors: Tuturop Maikel , Lantang Daniel , Kamarea Mesak 
Published: July 2021

This study was conducted to examine the effect of â€œkebenâ€ seed Baringtonia asiaticaÂ (L.) Kurz on mortality of flea (Coccus viridis) found in CoffeaÂ sp. Experimental methods with Complete Random Design (CRD) was used in this study. Five doses of â€œkebenâ€ seed extract (0.2%, 0.4%, 0.6% 0.8% and 0.0%) were used. Result of the study showed that all five concentration of â€œkebenâ€ extract were toxic to Coccus viridis, therefore can be used to control pest of coffe caused by Coccus viridis. Among the concentration used, it was found that concentration at 0.4% more effective than other concentrations. Consentration at 0.4% was killed 100% of Coccus viridisÂ population in 3 days.Key words: Barringtonia asiatica, Coccus viridis, Concentration of seed extract.Â
Kualitas Sumber Air Minum Masyarakat Kampung Yokiwa Distrik Sentani Timur Secara Bakteriologis
Authors: Patasik Ima F. , Lantang Daniel 
Published: July 2021

The aim of this study was to observe the presence of coliform bacteria and the level of contamination in outlet water of Sentani lake, especially in Jaifuri river. The study was done from Januari-April 2009 in 3 sampling areas: outlet of the lake (A), in between outlet and the river (B), and in Jaifuri river (C). Samples then be analized in Biology Laboratory, FMIPA University of Cenderawasih using MPN (Most Probable Number) series 3-3-3. Furthermore, the result then compared with the quality standard of dringking water (Peraturan Menteri Kesehatan RI No 416/MENKES/PER/IX1990). The result showed that coliform of sample A was 9.300 MPN/ 100 ml, sample B was 4.300 MPN/100 ml and sample C was 24.000 MPN/ 100 ml. That condition was above the maximum level of contamination of dringking water (0/100 ml). In addition, the biochemical test showed that Escherichia coliÂ and Klebsiella pneumoniae were found in that water samples.Â Â Key words: Coliform, Escherichia coli, outlet of Sentani lake, Jaifuri river, East Sentani.Â
Analisis Dimorfisme Kupu-Kupu Sayap Burung (Ornithoptera sp.) Endemik Papua
Authors: Warikar Evie L. , Ramandey Euniche R.P.F. , Maury Hendra K. 
Published: July 2021

OrnitopheraÂ sp. is one of the groups of butterflies endemic in Papua and West Papua provinces. The significant morphological differences between male and female butterflies (dimorphism) are in the shape, size and color of the wings. Morphological characteristics are important sources of information. Based on the results of specimen collections at the Papua Insect Collection Laboratory (KSP) Jayapura, there are several species from various locations in Papua. The variation in dimorphism is likely to occur in this species which gives rise to new sub-species. The purpose of this study was to record the dimorphism of the endemic Bird Wing of Papua which had been stored in the Papua Insect Collection Laboratory (KSP) Jayapura. The method used is a direct measurement of the morphology of bird wing butterfly specimens stored in the KSP Laboratory, Cenderawasih University. Morphometric data were analyzed using the SPSS 20 and Multi Variate Statistical PackageÂ (MVSP 3.1)Â programs. The results obtained were 7 Ornithoptera species stored in the KSP Jayapura Laboratory, namely O.Â chiamera, O. goliath, O. meridionalis, O. paradisea, O. priamus, O. thitonusÂ and O. rothschildi. Based on observations there are striking differences in color, shape and size between male and female in the same species.Â Â Â Key words:Â birdwing butterfly, OrnithopteraÂ sp., KSP Jayapura, dimorphisme.Â Â
Ekologi dan Kelimpahan Ikan Sentani Gudgeon (Oxyeleotris heterodon, Weber 1908) dan Snakehead Gudgeon (Giuris margaritacea, Valenciennes 1837) di Danau Sentani, Papua
Authors: Ohee Henderite L. , Ngamelubun Gerardinalia , Ansaka Joane J. , Korwa Novela H. , Sujarta Puguh 
Published: July 2021

Freshwater community in Lake Sentani comprise of 35 species including three endemic species, seven native species, eight anadromous fish and 17 introduced species. Two native species are Sentani Gudgeon (Oxyeleotris heterodon) and Snakehead Gudgeon (Giuris margaritacea). The survey aims to document the ecology and fish abundance of the gudgeons in Lake Sentani. Fish sampling was done passively by using gill nets with three different mesh sizes inÂ five locations;Â Puai, Enandowai, Waena, Ayapo and Yahim. Substrate type, water vegetations, habitat depth and fish abundance were recorded each locations. Substrate preferences of the gudgeons are sand, mud and gravel, whileÂ O. heterodonÂ was more abundance in sand mud substrate type. Moreover, water vegetation preference was different between O. heterodonÂ and G. margaritacea. Sentani Gudgeon prefer habitat with dense water vegetations, while G. margaritaceusÂ could be found in habitat with orÂ without water vegetation. Theses two gudgeons wereÂ found in relatively the same habitat depth, up toÂ 7 meters depth.Â O. heterodonÂ and G. margaritacea had a very low abundance in the lake.Â It is important to conserve lake area from the edge Â up to 7 meter depth that consist of sand, mud and gravel substrate types and dense water vegetation to ensure the population of these two gudgeons are abundance in Lake Sentani.Â Â Key words:Â Ecology, Lake Sentani, relative abundance,Â O. heterodon, G. margaritacea.
Uji bakteriologis air di PDAM GT Kabupaten Magelang dengan metode MPN Quanty-Tray
Authors: Mubarokhah Lailatul , Wijanarka Wijanarka 
Published: July 2021

Water is the main need for life. The bacteriological requirements for clean water are the presence or absence of Coliform bacteria and E. coliÂ in water. The purpose of this study was to determine the quality of water from gravity springs and pump springs as a source of water in Magelang Regency PDAM GTÂ and Magelang Regency community. This study was to finding out the bacteriological test of water in Magelang Regency PGT. This study was to know bacteriological water testing techniques using the MPN Quanti-method Tray in Magelang Regency PGT. The method used in this study is the Quanty-Tray Most Probable Number (MPN) method. The sample of this study were two gravitational springs namely Sample A and Sample B and two pumping springs namely Sample C and Sample D. The results of MPN calculations from the four springs did not meet the requirements of clean water ready to be distributed to the community because Coliform in the spring gravity water and pumps and found E. coliÂ in the pump spring water.Â Â Key words:Â coliform, MPNÂ quanty-tray, bacteriological requirement.
Aktivitas Antipiretik Ekstrak Etil Asetat Daun Seligi (Phyllanthus buxifolius Muell.Arg) Pada Mencit Jantan Galur Swiss
Authors: Hastuti Siwi , Endrawati Susi 
Published: July 2021

Seligi (PhyllanthusÂ buxifoliusÂ Muell. Arg) empirically proven to reduce pain and swelling in joints. The research of analgesic activity and antiinflammatory of seligi leaves was done, however antipyretic research not be found. The aim of this research was to examine the effect of ethyl acetate extract from seligi leaves as antipyretic on white male mice strain Swiss induced with DTP-HB-Hib vaccine. Ethyl acetate extract of seligi leaves doses of 100, 200 and 400 mg/kg showed antipyretic effect with values of 18.77 Â± 1.99, 24.81 Â± 4.34 and 35.39 Â± 2.84 % respectively whereas paracetamol dose of 91 mg/kg have antipyretic effect with value of 50.38 Â± 6.90 %. One way ANOVA test showed no significant difference for p (0.001) <p (0.05). Significance LSD Post hoc test for paracetamol 91 mg/kg with all seligi extract and extract seligi dose of 400 mg/kg with seligi extract 100 mg/kg have significant difference. While seligi extract 400 mg/kg with seligi extract 200 mg/kg and extract seligi 200 mg/kg with seligi extract 100 mg/kg no significant difference. Ethyl acetate extract of seligi leaves can be developed as source for active compounds with antipyretic activity.Key words:Â antipyretic, seligi, PhyllanthusÂ buxifolius, temperature, mice.Â