bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implications of the unexpected persistence of human rhinovirus/enterovirus during the COVID‐19 pandemic in Canada
Authors: Champredon David , Bancej Christina , Lee Liza , Buckrell Steven 
Published: November 2021

AbstractStringent public health measures imposed across Canada to control the COVID‐19 pandemic have nearly suppressed most seasonal respiratory viruses, with the notable exception of human rhinovirus/enterovirus (hRV/EV). Thanks to this unexpected persistence, we highlight that hRV/EV could serve as a sentinel for levels of contact rate in populations to inform on the efficiency, or the need of, public health measures to control the subsequent COVID‐19 epidemic, but also for future epidemics from other seasonal or emerging respiratory pathogens.
Protective effect of Idelalisib on carbon tetrachloride‐induced liver fibrosis via microRNA‐124‐3P/phosphatidylinositol‐3‐hydroxykinase signalling pathway
Authors: Li Xiaohe , Li Hailong , Zhang Shanshan , Zhang Ruotong , Li Jinhe , Wei Yiying , Yang Cheng , Zhang Fubo , Zhou Honggang 
Published: November 2021

AbstractLiver fibrosis is the repair process of abnormal connective tissue hyperplasia after liver damage caused by different causes. Inhibition of PI3K/Akt signalling pathway can reduce the deposition of extracellular matrix, inhibit the proliferation of hepatic stellate cells (HSCs), and promote its apoptosis to achieve the purpose of therapy. This study aimed to investigate the effect of Idelalisib (PI3K inhibitor) on carbon tetrachloride (CCl4)‐induced liver fibrosis in mice. We used CCl4‐induced liver fibrosis mouse model in vivo and TGF‐β1‐stimulated HSCs to evaluate the antifibrosis activity of Idelalisib. In vivo, Idelalisib significantly alleviated CCl4‐induced liver damage, collagen deposition, and hydroxyproline accumulation in mice. Immunohistochemistry and Western blot results showed that Idelalisib could significantly inhibit the expressions of COL1 and α‐SMA in a concentration‐dependent manner. In cell experiments, Idelalisib significantly inhibited the expressions of COL1, SMA, and p‐Smad3 in TGF‐β‐induced HSCs, thereby inhibiting HSC activation. Flow cytometry and Western blot results showed that Idelalisib significantly promoted TGFβ‐induced apoptosis of HSCs after 48 h of administration, but had no significant effect after 24 h. Idelalisib promoted the apoptosis of activated HSCs by inhibiting the PI3K/Akt/FOXO3 signalling pathway. To further explore the mechanism by which Idelalisib inhibited PI3K, we predicted the miRNA targeting PI3K through the database and crossed it with the down‐regulated miRNA reported in liver fibrosis mice in the past five years. Finally, we identified miR‐124‐3p and miR‐143‐3p. We then demonstrated that Idelalisib significantly promoted miR‐124‐3p and miR‐142‐3p in vitro and in vivo. Dual‐luciferase report analysis showed that Idelalisib significantly inhibited luciferase activity but had no significant effect on the luc‐MUT transfection assay. Finally, we demonstrated that Idelalisib reversed the effects of miR‐124‐3p inhibitor on the PI3K/Akt/FOXO3 asterisk pathway and caspase‐3. Idelalisib has potential as a candidate drug for alleviating liver fibrosis.
Comparison of physical and psychosocial function post‐treatment among oral cancer patients with low‐to‐moderate and high nicotine dependence
Authors: Peng Hsi‐Ling , Lee Li‐Yun , Huang Bing‐Shen , Lin Chien‐Yu , Chang Ya‐Lan , Chung Ching‐Fang , Chen Shu‐Ching 
Published: November 2021

AbstractPurposeAfter suddenly stopping smoking after an initial oral cancer (OC) diagnosis, patients may restart smoking and nicotine dependence. This study sought to identify factors associated with high nicotine dependence in OC patients who restarted smoking post‐treatment.DesignA cross‐sectional study.MethodsA group of 220 OC patients who restarted smoking post‐treatment were recruited from the outpatient radiation department of a single cancer center in northern Taiwan. Demographic and clinical characteristics were recorded, and patients were assessed for nicotine and smoking dependence, physical activity and function, socio‐emotional function, social support, and depression.ResultsAmong patients who restarted smoking after treatment for OC, 75.9% reported low‐to‐moderate dependence on smoking, while 24.1% reported high nicotine dependence. Factors associated with high nicotine dependence included higher incidence of smoking per day, greater dependence on smoking, less physical activity per week, and poorer social–emotional function. Those highly dependent on nicotine were younger, unmarried, had less education, and had begun smoking earlier than those with low‐to‐moderate nicotine dependence.ConclusionsThe amount of smoking per day, greater smoking behavioral dependence, less physical activity per week, and worse social–emotional function affected high nicotine dependence.Clinical relevanceSmoking cessation training and counseling for OC patients may help them better control their use of tobacco after treatment.
A review of multiunit auctions with homogeneous goods
Authors: Khezr Peyman , Cumpston Anne 
Published: November 2021

AbstractThis article provides a comprehensive survey of the literature on multiunit auctions with multiple homogeneous goods. Despite the importance of multiunit auctions, the research on these auctions attracted substantially less attention than single‐unit auctions. We start by providing a review of the theoretical literature on homogeneous good multiunit auctions where bidders have multiunit demands. The articles are categorized based on their models' assumptions regarding bidders' values and the type of auction. Furthermore, we review the empirical and experimental evidence related to these multiunit auctions to understand the relationship with the theoretical findings.
The Application of 3D Dense Face Alignment in Esthetic Rehabilitation
Authors: Liu Yushu , Chen Duo , Zhang Rui , Cui Xinyue , Zhou Yongsheng 
Published: November 2021

AbstractThis article describes a technique for making an esthetic treatment plan by using a virtual face scan reconstructed from digital photographs through three‐dimensional dense face alignment (3DDFA) and intraoral scans. Portrait photographs were captured with a digital camera and were reconstructed to a virtual 3D face scan by 3DDFA. After scaling the virtual face scan to the correct size, intraoral scans and virtual face scans were aligned to create a 3D view of the patient. A virtual diagnostic waxing was created accordingly. In select cases, this technique can provide 3D esthetic predictions when 3D face imaging devices are not available.
KH domain proteins: Another family of bacterial RNA matchmakers?
Authors: Olejniczak Mikolaj , Jiang Xiaofang , Basczok Maciej M. , Storz Gisela 
Published: November 2021

AbstractIn many bacteria, the stabilities and functions of small regulatory RNAs (sRNAs) that act by base pairing with target RNAs most often are dependent on Hfq or ProQ/FinO‐domain proteins, two classes of RNA chaperone proteins. However, while all bacteria appear to have sRNAs, many have neither Hfq nor ProQ/FinO‐domain proteins raising the question of whether another factor might act as an sRNA chaperone in these organisms. Several recent studies have reported that KH domain proteins, such as KhpA and KhpB, bind sRNAs. Here we describe what is known about the distribution, structures, RNA‐binding properties, and physiologic roles of KhpA and KhpB and discuss evidence for and against these proteins serving as sRNAs chaperones.
Imagining the Unimaginable: Origen’s Two Models of the Trinity
Authors: Maspero Giulio 
Published: November 2021

AbstractBoth the history of the Church and Dogmengeschichte witness to an ambiguity in the reception of Origen’s theology. But the last decades have offered new results, ranging from the discovery of the original Greek text of the homilies on the Psalms to the development of a relational and anti‐reductionist epistemology for the history of dogma. These developments make possible a new picture of the great Alexandrine’s theology more faithful to his intention, which can be grasped only through a prayer‐based approach, as in Sarah Coakley’s and Lorenzo Perrone’s works. Origen’s main concern was to identify the purely spiritual dimension with the Trinity, highlighting how Christian theology differentiates itself with respect to both Stoicism and Gnosticism. This brought Origen to formulate two main models for the Trinity: the triangular one and the linear one. Their interplay shows that it is impossible to divide Christology from Pneumatology, thereby inspiring the first attempts to systematize the doctrine of the triune God towards a relational picture. From this perspective, the fourth‐century criticisms by Athanasius and the Cappadocians of the political theology based on the Arian reading of the monarchy, allegedly according to Origen’s Trinitarian theology, can now be presented as a faithful (relational) development of the Alexandrine’s heritage.
In vitro antibacterial and antibiofilm effects of cold atmospheric microwave plasma against Pseudomonas aeruginosa causing canine skin and ear infections
Authors: Kim Eun‐Joo , Hyun Jae‐Eun , Kang Yeong‐Hun , Baek Seung‐Joon , Hwang Cheol‐Yong 
Published: November 2021

BackgroundPseudomonas aeruginosa is an opportunist pathogen that causes purulent inflammation in the skin and in the ears of dogs. Among the various virulence factors of P. aeruginosa, biofilms have been reported to result in antibiotic resistance, leading to therapeutic limitations. Cold atmospheric microwave plasma (CAMP) is known to have a high antimicrobial effect, which causes physical cell wall rupture and DNA damage.Hypothesis/ObjectivesThe objective of this study was to evaluate the antibacterial and antibiofilm effects of CAMP against planktonic bacteria and the biofilm of P. aeruginosa.Methods and materialsThe antibacterial effect of CAMP against P. aeruginosa ATCC10145 and clinical isolates (n = 30) was evaluated using the colony count method. We also assessed the effect of CAMP on biofilm of P. aeruginosa ATCC strain by the colony count method, water‐soluble tetrazolium salt (WST) assay and confocal laser scanning microscopy (CLSM).ResultsThe complete eradication of P. aeruginosa (ATCC strain and clinical isolates) was achieved within 120 s at 50 W, and clinical isolates required 60 s shorter than the ATCC strain for complete eradication at 50 W. We also confirmed the time‐dependent bactericidal effect of CAMP at 50 W against ATCC strain biofilm.Conclusions and clinical importanceCAMP was effective against both planktonic bacteria and biofilm formation of P. aeruginosa. However, further studies on in vivo efficacy and safety in canine skin and ears are necessary to fully validate its clinical application.
Phylogeography of Agathistoma (Turbinidae, Tegulinae) snails in tropical and southwestern Atlantic
Authors: Dornellas Ana P. , Graboski Roberta , Hellberg Michael E. , Lotufo Tito M. C. 
Published: November 2021

AbstractThe rocky intertidal gastropods Agathistoma viridulum and A. hotessierianum occur from the Caribbean to southern Brazil, with a gap in the equatorial region, giving them an anti‐tropical distribution. We used sequences from mitochondrial genes to elucidate the phylogeography of A. viridulum and A. hotessierianum and to infer their relationships to other species of Agathistoma. For A. hotessierianum, haplotype networks and phylogenetic analyses split samples into two distinct groups: one (A. hotessierianum) in the Caribbean region (Greater and Lesser Antilles; Venezuela: Sucre and Isla Margarita) and a new species that we describe from northeastern Brazil. For A. viridulum, genetic analyses split the samples into three groups (Caribbean, northeastern Brazil and southeastern Brazil), but genetic divergence among these was too low for them to be considered species, and morphological differences were not significant. The mtDNA tree identified two clades of eastern Pacific Agathistoma, but many lower‐level relationships within Agathistoma were not well resolved, suggesting that more complete taxon sampling and additional genetic data will be needed to establish more robust relationships among Tegulinae.
Effects of Soaking in Water, Base Oil, Ionic Liquid, and Grease of an Epoxy/UHMWPE/MoS2 Composite on Mechanical and Tribological Properties
Authors: Singh Neha , Sinha Sujeet K. 
Published: November 2021

Abstract
Liquid absorption and tribological studies of epoxy-based composite with ultra-high molecular weight polyethylene and MoS2, sliding against steel, were conducted. Composites, as coating and as a bulk, were soaked in water, base oil, ionic liquid, and lithium-based grease for different intervals of days or months. Liquid weight percent gain was more in polar liquids when compared to non-polar. Coated composite soaked in grease for 10 days showed coefficient of friction of 0.08 with wear life of more than 1 million cycles and wear-rate of 1.7 × 10−8 mm3/N m. Bulk polymer composite soaked in grease for 180 days provided the least coefficient of friction of 0.06 and specific wear-rate of 2.60 × 10−7 mm3/N m.
Analysis of Budget Disbursement Budget in The End of 2018 in Bangka Belitung Island Province
Authors: Tri SM Hendarti 
Published: November 2021

According to Permendagri No. 13 Year 2006 on the principles of general management of the financial area is the financial area which is managed in an orderly, obedient to the regulatory legislation, effective , efficient , economical, transparent and accountable to pay attention to the principles of fairness, appropriateness and usefulness to society . Regional financial management includes planning, determination, implementation, accountability , as well as guidance and supervision of the management of the regional budget. Due to the buildup of this budget disbursement, the Provincial Government of Bangka Belitung Islands is deemed necessary to conduct an evaluation related to the distribution of the budget. One of the factors causing the budget absorption cannot reach 100% is the auction process, which certainly involves rules and regulations. Another factor that causes low budget absorption is the inability of HR to manage tasks.
From the results of the research that has been done, it can be seen that the accumulation of budget disbursement at the end of 2018 has many negative impacts. One of them is the decline in the Bangka Belitung Islands Province Budget Implementation List (DIPA) for 2019 by 363.3 billion. The decline in DIPA occurred due to the lack of maximum Bangka Belitung Islands Provincial Government in maximizing DIPA revenue the previous year. This indicates the lack of good planning that has been made by the government resulting in budgetary congestion at the end of the year. One strategy to anticipate the low budget absorption is by maximizing the implementation of activities and not piling up activities at the end of the year.

Key words: Stacking of budget disbursement, APBN, withdrawal of funds at the end of the year.
An Overview of the Knowledge and Motivation of IMCI Staff Regarding the Implementation of IMCI at the Lubuk Buaya Public Health Center, Padang
Authors: Yuliarni Eza , Siregar Nurhayati , Sukmawati Yofa 
Published: November 2021

Introduction: Indonesia is one of the developing countries with a high under-five mortality rate due to the rough handling of Integrated Management of Childhood Illness (IMCI). Diseases that cause death can generally be treated at the hospital level, but it is still difficult at the public health center level. Public Health Centers have implemented (IMCI). Suppose they meet the criteria for implementing/implementing the IMCI approach at least 60% of the number of visits by sick toddlers. This study aimed to describe the knowledge and motivation of IMCI implementers regarding the implementation of IMCI at Lubuk Buaya Public Health Center, Padang, in 2014. Method: This research is descriptive. This research was conducted at the Lubuk Buaya Health Center Padang in May 2014. The population in this study were all IMCI implementers who were actively working at the Lubuk Buaya Public Health Center, Padang, with 37 people. Sampling with total sampling technique and analyzed univariately. Results: From 37 staff implementing IMCI, it was found that 31 (83.8%) staff had implemented IMCI well, 36 (97.3%) staff had high knowledge, and 23 (62.2%) staff had high motivation. Conclusions: This study shows that the knowledge and motivation of IMCI implementers are good in implementing IMCI. It is hoped that every IMCI implementer will further increase knowledge about IMCI and its performance so that all sick toddlers get the best IMCI services to prevent death in these toddlers.
Choice Of Reading Materials And Reading Achievement Of Junior High Students
Authors: Toyong Paul Junrey A. , Toyong Marino E. 
Published: November 2021

Reading is an important skill that can be used to communicate and understand the academic, business and cultural world. Reading can be a tool for learners’ progress and success in different fields of discipline. This study utilized descriptive-correlational design to examine 41 respondents selected as census or total enumeration using purposive sampling. Findings revealed that majority of the respondents used hard copy reading materials for the past 12 months. There were 22 respondents who used books, 2 who used magazines and 1 respondent used newspaper. Most of the class were in frustration level which is 75. 6%. There was one non-reader. Independent readers were four and instructional were five. There was a significant negative relationship (cc= -0.572 and p-value= 0.001) between choice of reading materials and reading achievement. This suggested that the use of soft copies as reading material is correlated to high reading achievement. The implications may serve as basis for intervention, program, and policy formulation. Teachers need to design interactive reading materials using the 21st Century technologies like soft copies reading materials which can be handy and can be access anytime and anywhere using mobile phones. Reading intervention using technology-based materials may be designed to improve reading achievement of the students. Schools may introduce e-library which may introduce various materials that can be accessed and read in soft copy format. This will also be beneficial to distance learning modality.
Personality and Academic Achievement level in Geography Subject at Secondary level
Authors: Guchait Prity 
Published: November 2021

This paper reports a relation between personality and academic achievement in geography subject at secondary level in which sample size is 170 from secondary school of Howrah district. A survey questionnaire was used to gather data. Result reflects that Academic achievement was significantly positive correlated with Extraversion vs. Introversion, Agreeableness vs. Antagonism, Conscientiousness vs. Lack of direction, Neuroticism vs. Emotional stability, and Openness vs. Closedness to experience.
A Comparative Analysis of Mean Percentage Scores (MPS) of Senior High School Classes
Authors: Raganit Ariel A. 
Published: November 2021

This comparative analysis on the Mean Percentage Scores (MPS) results of senior high school classes for Quarters I, II, and III was a good practice that can be emulated by educators in order to give meaning to the data. MPS is not for compilation only. It must be used for decision making in lesson delivery enhancements, learning resources utilization and school improvement plan and adjustment. The design used was descriptive research. This is a comparative analysis of the results of Quarterly Assessments of senior high school classes in a public school in Leyte with the sample of five sections determined by stratified sampling technique. Data were analyzed using Mean, standard deviation, dependent sample t-test, independent sample t-test, two-way Analysis of Variance (ANOVA) and thematic analysis of interviews of subject teachers. Descriptive study is scientific research that methodically deals with a certain region or population and characterizes an occurrence, phenomenon, or fact (Modato, 2017).
Based from interviews and document analysis, extracurricular activities, socio-cultural involvements, the difficulty of learning competences, and examination schedules and the school calendar in general all had an influence on students' performance. In addition, test structures, test layout, and clear directions and instructions have an impact on test results.
The Relationship of Learning Motivation, Reward and Achievement in Science of Secondary Students in The District of Botolan
Authors: Tolero Josue Alburo , Echaure Jessie S. 
Published: November 2021

ABSTRACT
The study aimed to determine the effect of learning motivation and reward to the achievement in Science among junior high school students of Botolan District, Division of Zambales during SY 2018-2019.
The study revealed that the respondent is a typical female. The respondents “strongly agree” on extrinsic, intrinsic and task value while “agree” on views about learning, self-efficacy and belief of achievement as dimensions of learning motivation. The respondents “agree” on tangible and intangible as dimensions on rewards system. The respondents “strongly agree” on indicators towards reward system. The students obtain a “passed” rating in their academic performance. There is no significant difference on the dimensions of learning motivation. There is no significant difference on the dimensions of reward system. There is no significant difference on the dimensions of reward system when grouped according to sex profile variable. There is no significant relationship between the academic performance and the dimensions on learning motivation.
The summary of the researches conducted and the assumptions arrived at, the researcher have to give tangible or intangible rewards to deserving students who are exerting efforts to excel in the science class that there is a necessity to train teachers in how to impart students so that they develop intrinsically motivated, as a substitute of just driven along by the idea of the next external reward; that the teachers are to exercise extreme fairness and equality to give rewards and recognition to deserving students.
Hibah Dalam Perspektif Hukum Perdata Islam
Authors: Hidayat Robist 
Published: November 2021

Hibah adalah merupakan suatu pemberian yang bersifat sukarela (tidak ada sebab dan musababnya) tnpa ada kontra prestasi dari pihak penerima pemberian, dan pemberian itu dilangsungkan pada saat si pemberi masih hidup (inilah yang membedakannya dengan wasiat, yang mana wasiat diberikan setelah si pewasiat meninggal dunia), Di dalam Kompilasi Hukum Islam, disebutkan hubungan hibah dengan waris terdapat dalam Pasal 211, yaitu :“Hibah dari orang tua kepada anaknya dapat diperhitungkan sebagai warisan.” Dengan demikian, bahwa ketentuan Pasal 211 Kompilasi Hukum Islam tentang hibah orang tua kepada anaknya, dapat diperhitungkan sebagai warisan. Hibah tersebut merupakan adat kebiasaan yang telah mengakar dan telah diterima oleh masyarakat Indonesia., adat istiadat semacam ini menurut kaidah-kaidah Hukum Islam disebut urf. Yang dimaksud dengan urf adalah segala sesuatu yang sudah dikenal oleh manusia, yang telah menjadi kebiasaan atau tradisi, baik bersifat perkataan, perbuatan atau dalam kaitannya dengan meninggalkan perbuatan tertentu. Urf disebut juga dengan adat (kebiasaan).