bluuebunny/crossref_metadata_2025_split huggingface dataset:
Colony structure, population structure, and sharing of foraging trees in the ant Myrmecia nigriceps (Hymenoptera: Formicidae)
Authors: Als V. , Narendra A. , Arthofer W. , Krapf P. , Steiner F. M. , Schlick-Steiner B. C. 
Published: August 2021

AbstractForaging ants face many dangers in search of food and often need to defend their prey to ensure the colony’s survival, although ants may also follow a peaceful foraging strategy. A non-aggressive approach is seen in the Australian bull ant Myrmecia nigriceps, in that workers of neighboring nests sometimes share foraging trees. In this study, we observed 31 nests at Mount Majura Nature Reserve in Canberra (Australia), 12 of which shared a foraging tree with at least one other nest in at least one of three nights. We genotyped 360 individuals at five published microsatellite loci and further established a set of nine polymorphic loci for M. nigriceps. Our results revealed a significant correlation between tree sharing and geographical distance between nests. We found no correlation between internest relatedness and tree sharing, geographical distance between nests and internest relatedness, and intranest relatedness and tree sharing. We further investigated the colony structure of M. nigriceps. All colonies were monodomous; the number of queens per colony ranged from one to two, and the number of fathers from one to three. No instances of worker drifting were found in this study.
Einfluss akzeptanzfördernder Interventionen auf die Nutzung einer Online-Selbsthilfe
Authors: Kreis Adina , Becker Jan , Beutel Manfred E. , Zwerenz Rüdiger 
Published: August 2021

Zusammenfassung
Hintergrund
Trotz wachsender empirischer Evidenz zur Wirksamkeit in der Behandlung psychischer Erkrankungen sind internetbasierte Interventionen (IBI) mit geringen Akzeptanz- und hohen Abbruchraten konfrontiert. Akzeptanzfördernde Interventionen (AFI) stellen eine vielversprechende Maßnahme dar, um die Akzeptanz zukünftiger Nutzer*innen zu verbessern. Die Wirksamkeit von AFI auf die Adhärenz, die maßgeblichen Einfluss auf die Wirksamkeit von IBI hat, wurde bisher in nur wenigen empirischen Untersuchungen überprüft.

Ziel der Arbeit (Fragestellung)
Ziel der vorliegenden Untersuchung ist die Überprüfung des Einflusses einer AFI auf die Akzeptanz, die initiale Nutzung und die Adhärenz des transdiagnostischen psychodynamischen Online-Selbsthilfeprogramms „Die Kraft der eigenen Emotionen nutzen (KEN-Online)“.

Material und Methoden
Es wurden Routinedaten von 231 Patient*innen ausgewertet, die während ihrer (teil‑)stationären Behandlung im Rahmen einer ins Routinesetting integrierten AFI das Angebot bekommen haben, KEN-Online behandlungsbegleitend zu nutzen. Im Kohortendesign werden Patient*innen, die an einer AFI teilgenommen haben, mit einer historischen Kontrollgruppe von Patient*innen verglichen, die dieses Angebot nicht erhielten. Zudem wird der Zusammenhang zwischen der Einstellung und der Akzeptanz des Programms in der Untersuchungsgruppe (mit AFI) überprüft.

Ergebnisse
Sowohl die Akzeptanz als auch die initiale Nutzung von KEN-Online waren um knapp 20 % höher (jeweils p < 0,01) unter den Teilnehmenden der AFI-Gruppe, verglichen mit der Kontrollgruppe. In Bezug auf die Adhärenz von KEN-Online zeigte sich ein kleiner Unterschied dahingehend, dass Teilnehmende der Kontrollgruppe signifikant (p < 0,05) mehr Einheiten abgeschlossen haben als Teilnehmende der Interventionsgruppe. Allerdings war der Anteil der „completer“ von KEN-Online mit 13,4 % insgesamt sehr gering. Ein Einfluss der Einstellung auf die Akzeptanz wurde nicht nachgewiesen.

Diskussion
Die vorliegende Untersuchung zeigt, dass AFI dazu beitragen können, die Akzeptanz und initiale Nutzung von IBI zu fördern, indem Patient*innen der (teil‑)stationären Routineversorgung standardisiert und strukturiert über die Intervention informiert werden. Hinsichtlich der Förderung der Adhärenz sind jedoch zusätzliche Maßnahmen erforderlich.
Subretinale Lufteingabe zur Behandlung postoperativer Netzhautfalten nach Ablatio
Authors: Radeck Viola , Helbig Horst , Prahs Philipp 
Published: August 2021

Zusammenfassung
Hintergrund
Faltenbildungen der Netzhaut stellen ein Problem v. a. nach Vitrektomie oder Buckelchirurgie mit Gaseingabe dar. Liegen diese Falten im Makulabereich, wirkt sich das meist erheblich auf das Sehvermögen des Patienten aus. Im Folgenden wird eine Behandlungstechnik solcher Falten beschrieben.

Methode
In einem Zeitraum von Januar 2017 bis Juni 2020 wurden 6 Patienten mit der im Folgenden beschriebenen Behandlungstechnik operiert. Es erfolgte die erneute Abhebung der Netzhaut mittels Balanced Salt Solution (BSS), gefolgt von einer subretinalen Eingabe gefilterter Luft. Das Ausstreichen der Falte erfolgte mithilfe von Perfluorcarbon (PFC). Eine postoperative Drainage der subretinalen Luft und Flüssigkeit erfolgte nicht, die Spontanresorption wurde abgewartet.

Ergebnisse
Bei keinem Patienten kam es zu einer Visusverschlechterung nach erneuter Netzhautabhebung. Eine Verbesserung der Sehschärfe zeigte sich bei 4 von 6 Fällen. Eine Verminderung der Metamorphopsien konnte bei 5 von 6 Patienten erreicht werden, 2 Patienten gaben an, die Metamorphopsien gar nicht mehr wahrzunehmen. Nur 1 Patient berichtete über einen gleichbleibend verzerrten Seheindruck trotz anatomisch glatter zentraler Netzhaut.

Schlussfolgerung
Bei kritischer Indikationsstellung stellt unsere Behandlungstechnik eine sichere und erfolgreiche Vorgehensweise zur Behandlung von Netzhautfalten im Bereich der Makula nach Ablatiooperation dar.
Entwicklung von Klassifikationskriterien für Uveitiden von der Standardization of Uveitis Nomenclature (SUN) Working Group
Authors: Heiligenhaus Arnd , Rothaus Kai , Pleyer Uwe 
Published: August 2021

Zusammenfassung
Hintergrund
Die Standardization of Uveitis Nomenclature (SUN) Working Group ist eine internationale Expertenkommission, die das Ziel verfolgt, eine standardisierte und international anerkannte Terminologie für das Gebiet der Uveitis zu erarbeiten. Dies erscheint angesichts der Forderung nach evidenzbasierter Medizin gerade bei relativ seltenen Erkrankungen wie der Uveitis wichtig.

Methoden
Unter Verwendung formaler Konsensustechniken wurde eine Datenbank von > 4000 Uveitispatienten erstellt, bei denen zuvor eine Mehrheitsübereinstimmung in der Diagnose erzielt wurde. Die Patientendaten wurden innerhalb der Uveitissubklasse analysiert und in einen Trainingssatz und einen Validierungssatz aufgeteilt. Mit maschinellem Lernen (ML) wurden multinomiale logistische Regressionen mit Lasso-Regularisierung auf dem Trainingssatz durchgeführt. Die Genauigkeit der Regeln, die entwickelt wurden, um die Kriterien des maschinellen Lernens auszudrücken, wurde von einem maskierten Beobachter in einer 10 %igen Zufallsstichprobe bewertet.

Ergebnisse
Die Schätzungen der Gesamtgenauigkeit nach Uveitisklassen im Validierungsset waren für alle Uveitisformen hoch: anteriore Uveitiden 96,7 % (95 %-Konfidenzintervall [CI] 92,4–98,6); intermediäre Uveitiden 99,3 % (95 %-CI 96,1–99,9); posteriore Uveitiden 98,0 % (95 %-CI 94,3–99,3); Panuveitiden 94,0 % (95 %-CI 89,0–96,8) und infektiöse posteriore Uveitiden/Panuveitiden 93,3 % (95 %-CI 89,1–96,3).

Schlussfolgerungen
Es werden Klassifikationskriterien präsentiert, die einen hohen Grad an Genauigkeit (geringe Fehlklassifikationsraten) aufweisen und sich daher gut für die künftige klinische und translationale Forschung eignen.
Long-term evaluation of pediatric ACL reconstruction: high risk of further surgery but a restrictive postoperative management was related to a lower revision rate
Authors: Hansson Frida , Moström Eva Bengtsson , Forssblad Magnus , Stålman Anders , Janarv Per-Mats 
Published: August 2021

Abstract
Introduction
The guidelines regarding rehabilitation after pediatric anterior cruciate ligament reconstruction (ACLR) are sparse. The aim of the study was to retrospectively describe the long-term outcome regarding further surgery and with special emphasis on the revision rate after two different postoperative rehabilitation programs following pediatric ACLR.

Material and methods
193 consecutive patients < 15 years of age who had undergone ACLR at two centers, A (n = 116) and B (n = 77), in 2006–2010 were identified. Postoperative rehabilitation protocol at A: a brace locked in 30° of flexion with partial weight bearing for 3 weeks followed by another 3 weeks in the brace with limited range of motion 10°–90° and full weight bearing; return to sports after a minimum of 9 months. B: immediate free range of motion and weight bearing as tolerated; return to sports after a minimum of 6 months.
The mean follow-up time was 6.9 (range 5–9) years. The mean age at ACLR was 13.2 years (range 7–14) years.
The primary outcome measurement in the statistical analysis was the occurrence of revision. Multivariable logistic regression analysis was performed to investigate five potential risk factors: surgical center, sex, age at ACLR, time from injury to ACLR and graft diameter.

Results
Thirty-three percent had further surgery in the operated knee including a revision rate of 12%. Twelve percent underwent ACLR in the contralateral knee. The only significant variable in the statistical analysis according to the multivariable logistic regression analysis was surgical center (p = 0.019). Eight percent of the patients at center A and 19% of the patients at B underwent ACL revision.

Conclusions
Further surgery in the operated knee could be expected in one third of the cases including a revision rate of 12%. The study also disclosed a similar rate of contralateral ACLR at 12%. The revision rate following pediatric ACLR was lower in a center which applied a more restrictive rehabilitation protocol.

Level of evidence
Case-control study, Level III.
Triple-negative breast carcinomas of low malignant potential: review on diagnostic criteria and differential diagnoses
Authors: Cima L. , Kaya H. , Marchiò C. , Nishimura R. , Wen H. Y. , Fabbri V. P. , Foschini M. P. 
Published: August 2021

AbstractTriple-negative breast carcinomas constitute a wide spectrum of lesions, mostly being highly aggressive. Nevertheless, some special histologic subtypes can have low malignant potential. The purpose of the present paper is to review diagnostic criteria and prognostic parameters of breast neoplasms of special histotypes. Specifically, adenoid cystic carcinoma, adenomyoepithelioma, acinic cell carcinoma, mucoepidermoid carcinoma, tall cell carcinoma with reverse polarity, and secretory carcinoma will be discussed. For each tumour, definition and morphological and molecular features, together with prognostic parameters, will be presented. Paradigmatic cases will be illustrated.
Combination of enamel matrix derivative and hyaluronic acid inhibits lipopolysaccharide-induced inflammatory response on human epithelial and bone cells
Authors: Ramenzoni Liza L. , Annasohn Laura , Miron Richard J. , Attin Thomas , Schmidlin Patrick R. 
Published: August 2021

AbstractObjectivesThe aim of this study was to evaluate the in vitro effect of enamel matrix derivative (EMD) and hyaluronic acid (HA) and their synergistic combination on lipopolysaccharides (LPS)-induced inflammation in human keratinocytes and osteoblasts.Material and methodsCells were challenged with LPS (1 μg/ml) and cultured in the following treatment groups with EMD (30 mg/ml) and HA (30 mg/ml): LPS, EMD, HA, EMD + HA, EMD + LPS, HA + LPS, and EMD + HA + LPS. Cell viability, inflammatory cytokine expression, and cell migration were determined using colorimetric assay, quantitative real-time polymerase chain reaction (qPCR), and scratch wound healing assay, respectively.ResultsCell viability was decreased when exposed to LPS compared to the controls. Overall, LPS treatment expressed upregulation on inflammatory cytokine tumor necrosis factor alpha (TNF-α), interleukin 1 beta (IL-1β), and interleukin 6 (IL-6). EMD and HA reduced up to 3.0-fold the cytokine expression caused by LPS (p < 0.05). EMD and HA statistically induced higher migration in osteoblasts and keratinocytes, respectively. Migration was impaired by LPS, whereas it significantly increased after addition of EMD and HA.ConclusionsEMD and HA are advantageous biomaterials that individually generate strong directional migratory keratinocyte and osteoblast response. Their combination also enhances cell viability, and anti-inflammatory and migratory abilities to promote healing specially under LPS inflammatory stimulus. Future in vivo and animal research is necessary to further characterize the effect of EMD and HA on periodontal regeneration.Clinical relevanceThe use of EMD in conjunction with HA resulted in a reduction of inflammation and improvement of tissue healing at wound sites. Both biomaterials combined may potentially improve the effectiveness of bone regeneration in periodontal bone defects, pointing to the potential clinical relevance of both materials in regenerative periodontal surgery.
Chitin and chitin-cellulose composite hydrogels prepared by ionic liquid-based process as the novel electrolytes for electrochemical capacitors
Authors: Kasprzak Dawid , Galiński Maciej 
Published: August 2021

AbstractThis paper reports on the preparation and electrochemical performance of chitin- and chitin-cellulose-based hydrogel electrolytes. The materials were prepared by a casting solution technique using ionic liquid-based solvents. The method of chitin dissolution in ionic liquid with the assistance of dimethyl sulfoxide co-solvent was investigated. The obtained membranes were soaked with 1-M lithium sulfate aqueous solution. The prepared materials were preliminarily characterized in terms of structural and physicochemical properties. Further, the most promising biopolymer membranes were assembled with activated carbon cloth electrodes in symmetric electrochemical capacitor cells. The electrochemical performances of these devices were studied in a 2-electrode system by commonly known electrochemical techniques, such as cyclic voltammetry, galvanostatic charge/discharge, and electrochemical impedance spectroscopy. The devices operated at a maximum voltage of 0.8 V. All the investigated materials have shown high efficiency in terms of specific capacitance, power density, and cyclability. The studied capacitors exhibited specific capacitance values in the range of 92–98 F g−1, with excellent capacitance retention (ca. 97–98%) after 20,000 galvanostatic charge and discharge cycles. Taking into account the above information and the eco-friendly nature of the biopolymer, it appears that the prepared chitin- and chitin-cellulose-based hydrogel electrolytes can be promising components for green electrochemical capacitors.
Relaxation Dynamics of Ethanol and N-Butanol in Diesel Fuel Blends from Terahertz Spectroscopy
Authors: Patiño-Camino Rayda , Cova-Bonillo Alexis , Rodríguez-Fernández José , Iglesias Teresa P. , Lapuerta Magín 
Published: August 2021

AbstractBinary blends of ethanol-diesel, n-butanol-diesel, ethanol-biodiesel, and n-butanol-biodiesel have been analyzed with terahertz time-domain spectroscopy in a full range of concentrations and at room temperature. The real and imaginary parts of the complex dielectric constant of the blends were obtained from the spectra and fitted to the Debye model at low volume concentrations (up to 7.5% for ethanol in diesel and up to 20% for butanol in diesel, ethanol in biodiesel, and butanol in biodiesel blends), considering the number of relaxation processes recommended in the literature for each pure component (single for diesel, double for biodiesel, and triple for alcohols). The results indicate that the faster relaxation time in low alcohol mixtures is longer than in pure alcohols. This relaxation time increases as the alcohol content increases. The excess of the real and of imaginary parts of the dielectric constant were individually determined. The analysis of such excess and of its different contributions (volume, contrast, and interactions) suggests that the intermolecular interactions between the different components of the blends dominate the relaxation dynamics in each pseudo-binary system. Ethanol was found to move blends further away from ideal behavior than n-butanol. In fact, these latter blends showed the most ideal behavior, suggesting that the length of the alcohol carbon chain plays an important role. This information allows a possible link between the nonlinear behavior of the physicochemical properties of the blends (e.g., viscosity and surface tension) and the molecular interactions between their constituent molecules. This relation could have direct application for monitoring the fuel composition and quality in the vehicle control systems.
An overview of machine learning techniques in constraint solving
Authors: Popescu Andrei , Polat-Erdeniz Seda , Felfernig Alexander , Uta Mathias , Atas Müslüm , Le Viet-Man , Pilsl Klaus , Enzelsberger Martin , Tran Thi Ngoc Trang 
Published: August 2021

AbstractConstraint solving is applied in different application contexts. Examples thereof are the configuration of complex products and services, the determination of production schedules, and the determination of recommendations in online sales scenarios. Constraint solvers apply, for example, search heuristics to assure adequate runtime performance and prediction quality. Several approaches have already been developed showing that machine learning (ML) can be used to optimize search processes in constraint solving. In this article, we provide an overview of the state of the art in applying ML approaches to constraint solving problems including constraint satisfaction, SAT solving, answer set programming (ASP) and applications thereof such as configuration, constraint-based recommendation, and model-based diagnosis. We compare and discuss the advantages and disadvantages of these approaches and point out relevant directions for future work.
Preparation and preliminary quality evaluation of aspirin/L-glutamate compound pellets
Authors: Xu Mengchang , Liu Fenglin , Zhou Wenhu , He Binsheng , Tan Songwen 
Published: August 2021

AbstractL-glutamate is an important component of protein. It can prevent gastrointestinal damage caused by NSAIDs. We constructed two-phase enteric-coated granules of aspirin and L-glutamate compound by extrusion spheronization method and fluidized bed coating. The subliminal effective dose of L-glutamate is 100 mg/kg tested by model of gastric ulcer of rats induced by aspirin and drug administration. HPLC-UV and UV–Vis methods were adopted to determine content and cumulative release of aspirin and L-glutamate as quality analysis method indexes. The prescription and process optimization were carried out with yield, sphericity and dissolution. The two-phase compound granules have good sphericity of 0.93 ± 0.05 (aspirin pellets) and 0.94 ± 0.02 (L-glutamate pellets), content of salicylic acid (0.24 ± 0.03)%, dissolution of aspirin (2.36 ± 0.11)%. Quality evaluation and preliminary stability meet the commercial requirements. The stored environment of compound preparation should be sealed in a cool and dark place.
In vivo biocompatibility of diamond-like carbon films containing TiO2 nanoparticles for biomedical applications
Authors: Wachesk C. C. , Seabra S. H. , Dos Santos T. A. T. , Trava-Airoldi V. J. , Lobo A. O. , Marciano F. R. 
Published: August 2021

AbstractHybrid diamond-like carbon (DLC) with incorporated titanium dioxide (TiO2) nanoparticle coatings have low friction coefficient, high wear resistance, high hardness, biocompatibility, and high chemical stability. They could be employed to modify biomedical alloys surfaces for numerous applications in biomedical engineering. Here we investigate for the first time the in vivo inflammatory process of DLC coatings with incorporated TiO2nanoparticles. TiO2-DLC films were grown on AISI 316 stainless-steel substrates using plasma-enhanced chemical vapor deposition. The coated substrates were implanted in CF1 mice peritoneum. The in vivo cytotoxicity and biocompatibility of the samples were analyzed from macrophage lavage. Analysis in the first weeks after implantation could be helpful to evaluate the acute cytotoxicity generated after a possible inflammatory process. The in vivo results showed no inflammatory process. A significant increase in nitric oxide production on the uncoated substrates was confirmed through cytometry, and the coated substrates demonstrated biocompatibility. The presence of TiO2nanoparticles enhanced the wound healing activity, due to their astringent and antimicrobial properties. DLC and TiO2-DLC coatings were considered biocompatible, and the presence of TiO2nanoparticles reduced the inflammatory reactions, increasing DLC biocompatibility.
The role of teacher identity in teacher self-efficacy development: the case of Katie
Authors: Marschall Gosia 
Published: August 2021

AbstractThis article illustrates the role of teacher identity in teacher self-efficacy development during initial teacher education. It has been posited that teacher self-efficacy develops on the basis of information accessed through four self-efficacy sources: vicarious and enactive experiences, social persuasion, and physiological and affective states, and by interacting with a myriad of personal and external factors. The very process of teacher self-efficacy development, however, is not well understood. This phenomenological longitudinal qualitative case study contributes to addressing this issue by illustrating how a pre-service secondary mathematics teacher’s teacher self-efficacy is affected by the way she sees herself. More specifically, the study illustrates how aspects of a strong student teacher identity negatively affect the pre-service teacher’s teacher self-efficacy appraisal, and how her teacher identity, emerging through the processes of autonomous role enactment and social verification, supports teacher self-efficacy development.
Wherein is the concept of disease normative? From weak normativity to value-conscious naturalism
Authors: Amoretti M. Cristina , Lalumera Elisabetta 
Published: August 2021

AbstractIn this paper we focus on some new normativist positions and compare them with traditional ones. In so doing, we claim that if normative judgments are involved in determining whether a condition is a disease only in the sense identified by new normativisms, then disease is normative only in a weak sense, which must be distinguished from the strong sense advocated by traditional normativisms. Specifically, we argue that weak and strong normativity are different to the point that one ‘normativist’ label ceases to be appropriate for the whole range of positions. If values and norms are not explicit components of the concept of disease, but only intervene in other explanatory roles, then the concept of disease is no more value-laden than many other scientific concepts, or even any other scientific concept. We call the newly identified position “value-conscious naturalism” about disease, and point to some of its theoretical and practical advantages.