bluuebunny/crossref_metadata_2025_split huggingface dataset:
Motivação para prática de exercício físico na pandemia COVID-19 de idosos ativos
Authors: Possamai Vanessa , Faria Borges Lucia , Kruger Gonçalves Andrea , Cardoso da Silva Priscilla 
Published: November 2021

Objetivo: Verificar associação entre a motivação para prática de exercício físico e o nível de atividade física durante a pandemia de COVID-19. Método: Foi realizado um estudo transversal descritivo. Participaram do estudo 98 idosos de um programa de extensão universitária. Foi aplicado questionário com questões fechadas sobre motivação à prática de exercício físico e o nível de atividade física durante a pandemia; através de um formulário on-line enviado aos participantes pelo aplicativo WhatsApp durante o primeiro semestre de 2020. Para análise estatística, foi utilizado o teste de qui-quadrado para independência pelo software IBM-SPSS Statistics Base v.20. (Comitê de Ética-Universidade nº39.373). Resultados: A amostra foi composta por 93% (n=91) do sexo feminino e 7% (n=7) sexo masculino, com média de idade de 72,19±6,30. Os resultados apontam que 10% (n=10) consideram-se sedentários, 35% (n=35) pouco ativos e 54% (n=53) ativos. Sobre a motivação para a prática de exercício físico 45% (n=45) consideraram que a sua motivação diminuiu, 32% (n=32) se manteve e 21% (n=21) aumentou. Observou-se que houve associação entre a diminuição da motivação para a prática de atividade física e o baixo de nível de atividade física na pandemia [X² (2)= 33,201; (p<0,000)], apresentando uma associação de 0,582 (58%) entre estas variáveis. Conclusão: Idosos com nível de atividade física considerados sedentários apresentaram-se menos motivados a realizar atividade física durante a pandemia de COVID-19. Nesta amostra, idosos ativos e pouco ativos oscilam sua motivação quanto a prática de atividade física, podendo limitar o seu engajamento a permanecer na atividade a longo prazo.
Inisiasi Implementasi Zenius sebagai Aplikasi Pembelajaran Online di SD Muhammadiyah Wonorejo
Authors: Anwar Fuad , Soeparmi Soeparmi , Cari Cari , Riyatun Riyatun , Suharyana Suharyana , Yunianto Mohtar , Darmanto Darmanto 
Published: November 2021

<p>Telah dilakukan inisiasi implementasi zenius yang merupakan aplikasi pembelajaran online di SD Muhammadiyah Wonorejo yang diikuti 17 Guru. Dalam kegiatan tersebut dibagi menjadi 2 tahap, tahap pengenalan Aplikasi berbasis Desktop untuk menu pengunjung, Guru, Murid dan Orang tua. Untuk menu Guru dilatih untuk mengelola kelas, mengunggah materi pembelajaran, membuat soal, melakukan penilaian siswa serta melakukan pelaporan nilai ke orang tua. Tahap berikutnya adalah pengenalan Aplikasi berbasis Android, di latihkan untuk menu Murid, berisi lihat materi pembelajaran, presensi, mengerjakan soal ujian dan mengetahui hasil ujian. Sebelum dilakukan pelatihan sebagian besar tidak memahami aplikasi pembelajaran online, setelah dilakukan pelatihan semua peserta memahami dan akan mengimplementasikan dalam proses pembelajaran di kelas.</p><p> </p>
A multi-proxy record of environmental change through the last 53,000 years recorded in the sediments of Lake Kanono, Northland, New Zealand
Authors: Evans Gianna , Augustinus Paul , Gadd Patricia , Zawadzki Atun , Ditchfield Amber , Shane Phil 
Published: November 2021

ABSTRACTLake sediment archives from Southern Hemisphere mid-latitude regions provide invaluable records of late Quaternary environmental change. Here, changes in depositional environment over the past ca. 53,000 years were reconstructed using a range of physical, sedimentological, geochemical, and μ-XRF elemental proxy datasets analyzed from lake sediment cores obtained from Lake Kanono, Northland, New Zealand. The Lake Kanono stratigraphy displays a terrestrial peat environment (ca. 53,700–6,670 cal yr BP), followed by a trend of increased influx of detrital sediment during the Late Glacial–Interglacial Transition (LGIT) at ca. 14,000 cal yr BP with a peak from ca. 12,000 to 9,000 cal yr BP driven by increasingly dry conditions. The increase in sediment influx continued during the early to mid-Holocene, leading to dune reactivation which altered the catchment dynamics of the region, leading to the inception of a shallow lake basin at ca. 6,670 cal yr BP. The timing of the formation of this lake basin can be associated with changes in intensity of the Southern Westerly Winds (SWW) and the appearance and increase in intensity of the El Niño Southern Oscillation (ENSO) after ca. 7,500–7,000 cal yr BP (Moy et al. 2002; Moreno et al. 2018). Drier conditions peaked from ca. 4,000 to 2,400 cal yr BP, possibly culminating in decreased lake levels that persisted from ca. 2,400 to 2,210 cal yr BP, renewed dune accumulation, and blocked stream outlets, resulting in a deep lake basin with thermal stratification that persisted to the present. Cluster analysis of the μ-XRF data demonstrates that the most prominent change in chemistry is near the onset of the Last Glacial Maximum (LGM) at ca. 26,700 cal yr BP associated with a transition to a drier, windier climate. The second most prominent change in the μ-XRF data is during the Polynesian phase of human settlement at ca. 612–575 cal yr BP (1338– 1375 CE). Hence, we can demonstrate the utility and power of a multi-proxy approach coupled with μ-XRF element data to interpret changing sediment sources to a lake basin. Such an approach allows rapid and reliable evaluation of catchment processes influenced by climate events and land-use changes at a resolution not available using other approaches.
Effects of Fritillaria Taipaiensis Long Term Single Planting on the Bacterial Diversity and Main Bio-chemical Factors in the Rhizospheric Soils
Authors: Zhou You , Mu Maojun , Yang Min , Yang Xiaohong , Zhang Hua , Guo Dongqin , Zhou Nong 
Published: November 2021

Abstract
Fritillaria taipaiensis is a traditional Chinese herbal plant. Germplasm degradation usually appears during its extended years of cultivation. Aiming to explore the mechanisms of the germplasm degradation, the bacterial diversities, bio-chemical characters in the rhizospheric soils of F. taipaiensis with different cultivation years from 1 to 5 were analyzed. The result showed the Chao1 and the ACE indices of the bacterial community had no significant difference among samples while the Shannon and Simpson indices declined with the cuntivation year; the dominant bacteria phylum was Proteobacteria, the remaining phyla were Chloroflexi, Nitrospirae, Planctomycetes, Actinobacteria, Gemmatimonadetes, Firmicutes, Verrucomicrobia, Bacteroidetes, and Acidobacteria; the relative abundances of the dominant bacterial genera changed obviously among samples; the bacterial community structures in the rhizospheric soils with cultivation years of 2 and 4 were significantly different from that in other samples; the content of organic matter, available N, available P, available K and the activities of urease, alkaline phosphatase in samples decreased with the cultivation years; the soil pH increased with the cultivation years to unsuitable for F. taipaiensis growth; the distance-based redundancy analysis showed the pH, organic matter content, available phosphorus content and urease activity were the primary factors in determining bacterial community composition, the intra group beta diversity of the rhizospheric bacteria increased after a initial decline with the cultivation year. These results indicated long term continuous cropping changed the bacterial community structure, fertility condition and soil enzyme activities in the F. taipaiensis rhizosphere soils, which could badly affect its growth.
Increased Tea Saponin Content Influences The Diversity and Function of Plantation Soil Microbiomes
Authors: Zhang Shouke , Kong Junqia , Li Zikun , Song Feng , He Xinhua , Chen Longfei , Guo Kai , Zhou Xudong 
Published: November 2021

Abstract
Background
Plant secondary metabolites (PSMs) can affect the structures and functions of soil microbiomes. However, the core bacteria associated with PSMs, and their corresponding functions have not been explored extensively. In this study, soil physicochemical properties, tea saponin contents, microbial community compositions, and microbial community functions of different-age Camellia oleifera plantation soils from representative regions were analyzed. We evaluated the effects of plantation age increase on PSM accumulation, and the subsequent consequences on the structures and functions of soil microbiomes.
Results
Plantation ages increase positively corresponded with accumulated tea saponin contents, with negative effects on soil physicochemical properties, and soil microbiome structures and functions. Older plantation soil microbiomes exhibited simpler structures, lower diversity, and relatively looser putative interactions based on network analysis. Clearly, the core functions of soil microbiomes transitioned to those associated with PSM metabolisms, while microbial pathways involved in cellulose degradation were inhibited. Degradation experiments further confirmed that older plantation soils exhibited the higher capacity on tea saponin degradation but poorer on furfural.
Conclusions
This study systematically explored the influences of PSMs on soil microbiomes via the investigation of key bacterial populations and their functional pathways. With the increase of planting years, increased tea saponin content simplified the soil microbiomes diversity, inhibited the degradation of organic matter, and enriched the genes related to the degradation of tea saponin. These findings significantly advance our understanding on PSMs-microbiome interactions and could provide fundamental and important data for sustainable management of Camellia plantations.
Leukocyte adhesive function in Intensive Care patients with non-infectious and infectious systemic inflammation
Authors: Li Anqi , Jacques Angela , Avalos Bárbara de la Peña , Ong Yih Rue , Elgass Kirstin , Saylor Emma , Meyer Jason , Walsham James , Denny Kerina , Lipman Jeffery , Cheng Qiang , Kruger Peter 
Published: November 2021

Abstract
Background: The lack of rapid and accurate diagnostic tools to distinguish infectious (known as sepsis) and non-infectious causes of inflammation in patients with systemic inflammation remains a significantly unmet clinic need, particularly in the intensive care unit (ICU). As a hallmark of inflammation, circulating leukocytes must be activated and undergo a cascade of interactions with blood vessel endothelium before transmigrating into surrounding tissues, a process called leukocyte recruitment. Given the divergent disease aetiologies, it was hypothesised that the ability of circulating leukocytes to interact with endothelial cells and cause inflammation may differ when responding to infectious and non-infectious inflammatory stimuli, providing potential markers to differentiate these two diseases. ﻿Methods: In the present study, a flow-based blood testing platform, named leukocyte adhesive function assay (LAFA), was used to mimic blood microcirculation in vitro so that the patient leukocyte ability to interact with multiple endothelial molecules, including P+E selectins, VCAM-1 and IL-8, can be studied. The leukocyte adhesive functions of multiple leukocyte subsets were quantitatively assessed using a range of cell kinetic parameters, including cell speed, straightness, dwell time etc.Results: When analysed on P+E selectin substrate, a significantly lower value of cell straightness was observed in septic CD4 cells than non-infectious cells (0.78±0.04 vs 0.92±0.01, p < 0.01), suggesting a difference in CD4 cells ability to adhere to selectins in infectious and non-infectious patients. Additionally, an impaired ability to respond to IL-8 was observed in septic neutrophils compared to non-infectious cells, evidenced by a significantly reduced cell dwell time (91.7±14.0 vs 150.6±19.0 seconds, p < 0.05).Conclusions: Thus, our study promisingly showed the ability of LAFA to detect different adhesive function between leukocytes from ICU patients with infectious and non-infectious systemic inflammation. LAFA generated a number of novel markers that might distinguish infectious inflammation from non-infectious causes that warrant further study and novel opportunities for the rapid and accurate diagnosis of sepsis.
From a Long-distance Threat to the Invasion Front: Invasive Aedes Mosquito Species in Belgium Between 2007 and 2020
Authors: Deblauwe Isra , De Wolf Katrien , De Witte Jacobus , Schneider Anna , Verlé Ingrid , Vanslembrouck Adwine , Smitz Nathalie , Demeulemeester Julie , Loo Thomas Van , Dekoninck Wouter , Krit Meryam , Madder Maxime , Müller Ruth , Bortel Wim Van 
Published: November 2021

Abstract
Background: Invasive mosquito species (IMS) and their associated mosquito-borne diseases are emerging in Europe. In Belgium, the first detection of Aedes albopictus occurred in 2000 and of Aedes japonicus in 2002. Early detection and control of these IMS at points of entry (PoE’s) are of paramount importance to slow down any possible establishment. This paper gives an account of the IMS surveillance in Belgium between 2007 and 2020 and reviews the introductions and establishments recorded in that period.Methods: In total 52 PoE’s were monitored at least once for the presence of IMS between 2007 and 2020. These included used tyre and lucky bamboo import companies, airports, ports, parking lots along highways, shelters for imported cutting plants, wholesale markets, industrial areas, recycling areas, and cemeteries and an allotment garden at the country border with colonised areas. In general, monitoring was performed between April and November. Mosquitoes were captured with adult and oviposition traps, as well as by larval sampling. A logistic regression was performed to investigate the percentage of positive PoE’s for Ae. albopictus over the years. Results: Aedes albopictus has been detected at ten PoE’s, Ae. japonicus at three PoE’s and Aedes koreicus at two PoE’s. The latter two species have established overwintering populations. The percentage of PoE’s positive for Ae. albopictus increased significantly over time. Aedes albopictus is currently entering Belgium through lucky bamboo trade, used tyre trade and passive ground transport, while Ae. japonicus only through the latter two pathways. In Belgium, the import through passive ground transport was first recorded in 2018 and its importance seems to grow.Conclusion: Belgium is currently at the invasion front of Ae. albopictus and Ae. japonicus. The surveillance and control management actions at well-known PoE‘s associated to long-distance introductions are more straightforward than at less-defined PoE’s associated with short-distance introductions from colonised areas. These latter PoE’s represent a new challenge for IMS management in Belgium in the coming years and stresses the urgence of implementing a sustainable, structured and long-term IMS management programme, integrating active and passive surveillance and control.
Can Southeast Asia continue to be a major rice bowl?
Authors: Yuan Shen , Stuart Alexander , Laborte Alice , Edreira Juan Rattalino , Dobermann Achim , Kien Le Vu Ngoc , Thúy Lưu Thị , Paothong Kritkamol , Traesang Prachya , Myo Tint Khin , Su San Su , II Marcelino Villafuerte , Quicho Emma , Pame Anny , Then Rathmuny , Flor Rica , Thon Neak , Agus Fahmuddin , Agustiani Nurwulan , Deng Nanyan , Li Tao , Grassini Patricio 
Published: November 2021

Abstract
Southeast Asia is a major rice-producing region, with high level of internal consumption and accounting for 40% of global rice exports. Limited land resources, climate change, and yield stagnation during recent years have once again raised concerns about the capacity of the region to meet the growing demand for rice and remain as a large net exporter. Here we use a modelling approach to map rice yield gaps and assess production potential and net exports by 2040. We find that the average yield gap represents 48% of the yield potential estimate for the region. Exploitable yield gaps are relatively large in Cambodia, Myanmar, Philippines, and Thailand, but comparably smaller in Indonesia and Vietnam. Continuation of current yield trends will not allow Indonesia and Philippines to meet their domestic rice demand. In contrast, closing the exploitable yield gap would allow all countries to achieve rice self-sufficiency, with an aggregated annual rice surplus of 100 million tons available for export. Our study provides insights for increasing regional production on existing cropland by narrowing existing yield gaps.
Low Baseline Ischemic Water Uptake is Directly Related to Overestimation of CT Perfusion-Derived Ischemic Core Volume
Authors: McDonough Rosalie V. , Elsayed Sarah , Meyer Lukas , Ewers Theresa , Bechstein Matthias , Kniep Helge , Nawka Marie Teresa , Faizy Tobias D. , Schön Gerhard , Thomalla Götz , Fiehler Jens , Hanning Uta , Kemmling Andre , Broocks Gabriel 
Published: November 2021

Abstract
Background

Computed-tomography perfusion (CTP) is frequently used to screen acute ischemic stroke (AIS) patients for endovascular treatment (EVT), despite known problems with ischemic “core” overestimation. This potentially leads to the unfair exclusion of patients from EVT. We propose that net water uptake (NWU) can be used in addition to CTP to more accurately assess the extent and/or stage of tissue infarction.
Methods

Patients treated for AIS between 06/2015-07/2020 were retrospectively analyzed. Baseline CTP-derived core volume (pCore) and NWU were determined. Logistic regression tested the relationship between baseline clinical and imaging variables and core-overestimation (primary outcome). The secondary outcomes comprised 90-day functional independence (modified Rankin score) and lesion growth.
Results

284 patients were included. Median NWU was 7.2% (IQR:2.6–12.8). ASPECTS (RR:1.28,95%CI:1.09-1.51), NWU (RR:0.94,95%CI:0.89-0.98), onset to recanalization (RR:1.00,95%CI:0.99-1.00) and imaging (RR:1.00,95%CI1.00-1.00) times, and pCore (RR:1.02,95%CI:1.01-1.02) were significantly associated with core overestimation. Core-overestimation was more likely to occur in patients with large pCores and low NWU at baseline. NWU was significantly correlated with lesion growth.
Conclusion

NWU can be used as a supplemental tool to CTP during admission imaging to more accurately assess the extent of ischemia, particularly relevant for patients with large CTP-defined cores who would otherwise be excluded from treatment.
Bright--Dark Solitons in the Space-Shifted Nonlocal Coupled Nonlinear Schrodinger Equation
Authors: Ren Ping , Rao Jiguang 
Published: November 2021

Abstract
Multiple bright-dark soliton solutions in terms of determinants for the space-shifted nonlocal coupled nonlinear Schro¨dinger (CNLS) equation are constructed by using the bilinear (Kadomtsev-Petviashvili) KP hierarchy reduction method. It is found that the bright-dark two-soliton only occur elastic collisions. Upon their amplitudes, the bright two solitons only admit one pattern whose amplitude are equal, and the dark two solitons have three different non-degenerated patterns and two different degenerated patterns. The bright-dark four-soliton is the superposition of the two-soliton pairs and can generated bound-state solitons. The multiple double-pole bright-dark soliton solutions are generated through the long wave limit of the obtained bright-dark soliton solutions, and their collision dynamics are also investigated.PACS 02.30.Jr · 03.75.Lm · 04.20.Jb · 05.45.Yv
MR Susceptibility Imaging for Detection of Tumor-Associated Macrophages in Glioblastoma
Authors: Nazem Amir , Guiry Samantha , Pourfathi Mehrdad , Ware Jeffrey B. , Anderson Hannah , Iyer Srikant Kamesh , Moon Brianna F , Fan Yi , Witschey Walter R. , Rizi Rahim , Bagley Stephen J. , Desai Arati , O’Rourke Donald M. , Brem Steven , Nasrallah MacLean , Nabavizadeh Ali 
Published: November 2021

Abstract
Purpose
Tumor-associated macrophages (TAMs) are a key component of glioblastoma (GBM) microenvironment. Considering the differential role of different TAM phenotypes in iron metabolism with the M1 phenotype storing intracellular iron, and M2 phenotype releasing iron in the tumor microenvironment, we investigated MRI to quantify iron as an imaging biomarker for TAMs in GBM patients.
Methods
21 adult patients with GBM underwent a 3D single echo gradient echo MRI sequence and quantitative susceptibility maps were generated. In 3 subjects, ex vivo imaging of surgical specimens was performed on a 9.4 Tesla MRI using 3D multi-echo GRE scans, and R2* (1/T2*) maps were generated. Each specimen was stained with hematoxylin and eosin, as well as CD68, CD86, CD206, and L-Ferritin.
Results
Significant positive correlation was observed between mean susceptibility for the tumor enhancing zone and the L-ferritin positivity percent (r =0.56, p=0.018) and the combination of tumor’s enhancing zone and necrotic core and the L-Ferritin positivity percent (r=0.72; p=0.001). The mean susceptibility significantly correlated with positivity percent for CD68 (ρ = 0.52, p=0.034) and CD86 (r=0.7 p=0.001), but not for CD206 (ρ = 0.09; p=0.7). There was a positive correlation between mean R2* values and CD68 positive cell counts (r =0.6, p=0.016). Similarly, mean R2* values significantly correlated with CD86 (r=0.54, p=0.03) but not with CD206 (r=0.15, p=0.5).
Conclusion
MR quantitative susceptibility mapping can quantify the iron content of GBM and provide a non-invasive method for TAM quantification and phenotyping.
Prognostic Factors For Intermediate-Risk Atypical Meningiomas Determining Early Postoperative Adjuvant Radiotherapy Versus Active Monitoring After Gross Total Resection
Authors: Gurses Muhammet Enes , Zengin Hatice Yagmur , Shıkhaliyeva Aysel , Askun Cengiz Savas , Mut Melike 
Published: November 2021

Abstract
Background

Atypical meningiomas (AMs) constitute 18% of meningiomas. Predictors of recurrence are still indeterminate, and the timing of RT whether to treat with radiation upfront or at initial recurrence remains controversial, especially after gross total resection (GTR).
Methods

A retrospective study of AMs with uni-and multivariate analyses was conducted with clinical, surgical, radiological, and histopathological parameters. The prognostic factors associated with increased risk of recurrence were elucidated in the whole series and in the subgroup with GTR only.
Results

Subtotal resection (STR), skullbase-tentorium localization, no adjuvant RT, and progesterone-negativity caused tumor recurrence in 37 patients with a median follow-up of 48 (2-120) months. Among subgroup of 23 patients GTR only, 30.8% showed recurrence in a median of 39.65 months. AMs with a preoperative volume ≥27.5 cm3 disclosed a significantly higher risk of recurrence (a 9.3 fold increase) than those with <27.5 cm3 (66.7% vs. 14.3%, respectively). Skullbase-tentorium localization and progesterone negativity tend to have higher recurrence rates after GTR.
Conclusions

Preoperative volume was found to be a prognostic factor for AMs with a cut-off value of 27.5 cm3 for the first time in the literature. Our results disclosed that RT could be delayed with active monitorization after GTR for AMs, which are smaller than 27.5 cm3, not localized in skullbase-tentorium and progesterone-positive. Otherwise, early postop RT would be a safer approach without waiting the recurrence for AMs.