bluuebunny/crossref_metadata_2025_split huggingface dataset:
Personalized Mastery Learning Ecosystems: Using Bloom’s Four Objects of Change to Drive Learning in Adaptive Instructional Systems
Authors: Betts Anastasia , Thai Khanh-Phuong , Gunderia Sunil 
Published: July 2021

AbstractAdaptive instructional systems (AISs) hold tremendous promise for addressing learner variability at scale. Many AISs are grounded in Benjamin Bloom’s (1971) Mastery Learning approach, which delivers differentiated instruction, appropriate scaffolding, and feedback to ensure each child masters each concept or skill before moving on. (Bloom’s 1984) framework for learning went beyond the immediate interactions of learners and the AIS. He described “four objects of the change process” that must be addressed to significantly improve student learning: the learner, the materials, the teacher, and the learner’s environment, where parents/caretakers are a critical component, especially for young children. This paper describes a learning engineering approach to craft a Personalized Mastery-Based Learning Ecosystem (PMLE) that uses all people, processes, data, and networked connections to create new capabilities, richer experiences, and unprecedented educational opportunities for children and their families. This ecosystem treats all individuals within the system as learners (child, parent, teacher, etc.) whose knowledge and expertise can be enhanced to benefit the child’s learning. The PMLE enables parents and teachers to become empowered “agents” of change by providing them with knowledge, tools, and evidence-based strategies to support meaningful and effective interactions with the child, all driven by real-time data about the readiness of the child. This paper presents a vision of how AISs can move beyond working solely with the child to become more robust ecosystems that empower all agents of change to optimize personalization and ensure long-term success of all children at scale.
The Technical Challenges in OOP Application Across the European Union and the TOOP OOP Architecture
Authors: Tepandi Jaak , Rotuna Carmen , Sellitto Giovanni Paolo , Fieten Sander , Prentza Andriana 
Published: July 2021

AbstractThe Once-Only Principle requires the public administrations to ensure that citizens and businesses supply the same information only once to the Public Administration as a whole. Widespread use of the Once-Only Principle has the potential to simplify citizens’ life, make businesses more efficient, and reduce administrative burden in the European Union. The Once-Only Principle project (TOOP) is an initiative, financed by the EU Program Horizon 2020, to explore the possibility to enable the cross-border application of the Once-Only Principle by demonstrating it in practice, through the development of selected piloting applications for specific real-world use cases, enabling the connection of different registries and architectures in different countries for better exchange of information across public administrations. These piloting ICT systems are designed as a result of a pan-European collaboration and they adopt a federated model, to allow for a high degree of independence between the participating parties in the development of their own solutions. The main challenge in the implementation of an OOP solution is the diversity of organizations, procedures, data, and services on all four main levels of interoperability: legal, organizational, semantic, and technical. To address this challenge, TOOP is developing and testing the TOOP Reference Architecture (TOOPRA) to assist organizations in the cross-border implementation of the OOP. The paper outlines the TOOPRA users, principles, and requirements, presents an overview of the architecture development, describes the main views of TOOPRA, discusses architecture profiling, and analyses the TOOPRA sustainability issues.
Chronische Kreuzschmerzen – Nutzertypen ambulanter Versorgung
Authors: Daniel T. , Koetsenruijter J. , Wensing M. , Wronski P. 
Published: July 2021

Zusammenfassung
Hintergrund
Chronische Kreuzschmerzen (engl. „chronic low back pain“; Abk. CLBP) zählen zu den häufigsten muskuloskeletalen Erkrankungen. Die ambulante Regelversorgung sieht bisher keine strukturierte multimodale Versorgung vor, wobei eine multimodale Therapie empfohlen wird.

Ziel der Arbeit
Es sollte die Inanspruchnahme ambulanter Regelversorgung im ersten Jahr von neu erkrankten Patienten mit CLBP hinsichtlich des multimodalen Behandlungsansatzes exploriert und Nutzertypen bestimmt werden.

Material und Methoden
Eine Two-step-Clusteranalyse wurde mit Routinedaten von 11.182 inzidenten Fällen durchgeführt. Das Alter lag zwischen 18 und 65 Jahren und Daten von vier aufeinander folgenden Quartalen je Patient wurden analysiert. Anhand der Abrechnungsdaten von Orthopäden, Schmerztherapeuten, Psychotherapeuten, Heilmitteln, Schmerzmedikamenten und Opioiden wurden die Cluster ermittelt. Merkmale der Versorgungsstruktur und der Versicherten lieferten die weiteren Ergebnisse.

Ergebnisse
Die Analyse ergab vier Nutzertypen: 39,7 % nahmen keine fachärztliche Versorgung und wenige Heilmittel in Anspruch; 37,3 % wurden orthopädisch versorgt; 15,6 % nahmen orthopädische und schmerztherapeutische Versorgung in Anspruch; 7,4 % wurden orthopädisch, schmerz- und/oder psychotherapeutisch versorgt. Charakteristisch für eine multimodale Inanspruchnahme war: weiblich, hoher Schmerzmittelverbrauch (M = 143,94 DDD), hoher Opioidverbrauch (M = 37,12 DDD), hohe Heilmittelkosten (M = 631,79 €), Akupunktur, Antidepressiva, Hospitalisierung, interdisziplinäre Fallkonferenzen und Konsultationen bei Neurologen. 60,4 % der Studienpopulation nahmen Schmerzmittel ein.

Diskussion
Das Clusterverfahren zeigte unterschiedliche Nutzertypen. Die empfohlene multimodale Therapie erhielten circa 23 % der Studienpopulation.
Multilevel modeling of geographic information systems based on international standards
Authors: Alvarado Suilen H. , Cortiñas Alejandro , Luaces Miguel R. , Pedreira Oscar , Places Angeles S. 
Published: July 2021

AbstractEven though different applications based on Geographic Information Systems (GIS) provide different features and functions, they all share a set of common concepts (e.g., spatial data types, operations, services), a common architecture, and a common set of technologies. Furthermore, common structures appear repeatedly in different GIS, although they have to be specialized in specific application domains. Multilevel modeling is an approach to model-driven engineering (MDE) in which the number of metamodel levels is not fixed. This approach aims at solving the limitations of a two-level metamodeling approach, which forces the designer to include all the metamodel elements at the same level. In this paper, we address the application of multilevel modeling to the domain of GIS, and we evaluate its potential benefits. Although we do not present a complete set of models, we present four representative scenarios supported by example models. One of them is based on the standards defined by ISO TC/211 and the Open Geospatial Consortium. The other three are based on the EU INSPIRE Directive (territory administration, spatial networks, and facility management). These scenarios show that multilevel modeling can provide more benefits to GIS modeling than a two-level metamodeling approach.
Ethical concerns in rescue robotics: a scoping review
Authors: Battistuzzi Linda , Recchiuto Carmine Tommaso , Sgorbissa Antonio 
Published: July 2021

AbstractRescue operations taking place in disaster settings can be fraught with ethical challenges. Further ethical challenges will likely be introduced by the use of robots, which are expected to soon become commonplace in search and rescue missions and disaster recovery efforts. To help focus timely reflection on the ethical considerations associated with the deployment of rescue robots, we have conducted a scoping review exploring the relevant academic literature following a widely recognized scoping review framework. Of the 429 papers identified by the first screening, six fulfilled the selection criteria of our literature review. Quantitative data synthesis showed that a subset of the papers includes a qualitative experimental exploration of the ethical issues at hand, with workshops involving both experts and potential users. Most use simulations or scenarios to anticipate the ethical implications and other consequences of using robots in search and rescue missions. Qualitative text analysis identified seven core ethically relevant themes: fairness and discrimination; false or excessive expectations; labor replacement; privacy; responsibility; safety; trust. Our results suggest that the literature on ethics in rescue robotics is scant and disparate, but the papers identified uniformly endorsed a proactive approach to handling the ethical concerns associated with the use of robots in disaster scenarios.
Epigenomic stability assessment during cryopreservation and physiology among various strains of Chromochloris zofingiensis (Chlorophyceae) and their genetic variability revealed by AFLP and MS-AFLP
Authors: Reichelt Niklas , Leger Dorian , Daubert Mareike , Ruffino Paolo , Pröschold Thomas , Darienko Tatyana 
Published: July 2021

AbstractChromochloris zofingiensis (Dönz) Fucíková & L.A.Lewis, due to its production of highly valuable carotenoids such as astaxanthin, is a model organism in biotechnology. Since the recognition of this physiological property, many biotechnological applications have only used a single strain (SAG 211-14 = CCAP 211/14 = UTEX 32 = ATCC 30412) to produce biomass and carotenoids. However, multiple acquisitions of strains putatively belonging to the same species raised the question of the conspecificity of those strains and their properties. In this study, the conspecificity of the available strains, which are deposited axenically in SAG, was tested using SSU and ITS rDNA sequencing and AFLP (EcoRI/PstI) analyses. The comparison of SSU and ITS rDNA sequences as well as the AFLP patterns revealed that the investigated strains formed two very similar groups, (1) SAG 211-14, SAG 4.80, SAG 31.80, and SAG 34.80 and (2) SAG 221-2. All strains belonged to one species, C. zofingiensis, and represented one monophyletic lineage within the so-called DO-group of the Chlorophyceae. The robustness to cryopreservation and the subsequent epigenetic variability was detected using the methylation-sensitive AFLP (EcoRI/MspI and EcoRI/HpaII) among the five Chromochloris strains. All strains showed a high rate of survival (54.4–98.1%) during cryopreservation. The methylation patterns varied between precryo and postcryo in all strains detected among three time points (before, shortly after, and 8 weeks after cryopreservation), showing that the MS-AFLP technique has the potential to detect epigenetic effects occurring in response to cryopreservation and other stresses. Finally, the potential of these five strains for usage in biotechnological applications was proven by growing them in aerated cultures with and without additional carbon dioxide supply. The comparison showed that all strains produced high amounts of biomass and carotenoids under aeration with additional CO2 and were therefore suitable in biotechnology.
Improvement of Impulsivity and Decision Making by Transcranial Direct Current Stimulation of the Dorsolateral Prefrontal Cortex in a Patient with Gambling Disorder
Authors: Salatino Adriana , Miccolis Roberta , Gammeri Roberto , Ninghetto Marco , Belli Francesco , Nobili Marcello , Mouraux André , Ricci Raffaella 
Published: July 2021

AbstractGambling disorder (GD) is a form of behavioral addiction. In recent years, it has been suggested that the application of transcranial Direct Current Stimulation (tDCS) to the dorsolateral prefrontal cortex (DLPFC), which plays a key role in top-down inhibitory control and impulsivity, may represent a new therapeutic approach for treating addictions. Here we investigated the effectiveness of a novel low dose tDCS protocol (i.e. six sessions of right anodal/left cathodal tDCS for 20 min, with a current intensity of 1 mA) applied to DLPFC in a patient with GD. To evaluate the effect of the proposed intervention, cognitive, psychological and behavioural evaluations were performed at different time points, pre and post intervention. The results showed improvement of impulsivity, decision making, and cognitive functioning after tDCS intervention. Findings of the present study suggest that low doses of right anodal/left cathodal tDCS to DLPFC may effectively improve gambling behaviour. They also suggest to carefully evaluate the effects of this tDCS polarity on the patient’s emotional state. The current protocol warrants further investigation in large groups of patients, as it may provide relevant insights into the design of effective, low dose treatments of gambling disorder.
A novel test rig to study the effect of fretting wear on the forced response dynamics with a friction contact
Authors: Tamatam Lakshminarayana Reddy , Botto Daniele , Zucca Stefano 
Published: July 2021

AbstractThis paper presents a novel test rig to study the effect of fretting wear and of the contact surface evolution on the forced response of systems with dry friction contact. This rig allows simulating contacts similar to the type of contacts present between the shrouds at the blade tip. Several research groups have been studying how fretting wear affects the dynamic response of mechanical systems, developing numerical prediction tools that consider dry friction contact and nonlinearity. The aim of this work is to experimentally study the evolution of contact interfaces and how this evolution affects the system dynamics. Experimental results will aid to validate the numerical predictions. The test rig developed for this activity is made of a cantilever beam fixed at one end and with a friction contact at the free end. The contact couple is made of two replaceable specimens. The contact is loaded via a lifting mechanism through a screw with fine thread. Fretting wear test was performed at a constant frequency and force amplitude, exciting the beam with an electromagnetic shaker. To emphasize the change of the dynamic response, frequency sweeps were performed at various intervals during the wear test. The full range test with ‘changing preload’ due to progressing wear was performed until a full loss of contact. This paper describes the test rig design, intent, set-up, instrumentation, test plan and results. Results include the frequency response curves for unworn contact, wear profiles at multiple intervals and the effect of wear on the frequency response. Though energy dissipation per cycle is quite small, wear leads to material loss at the contact with a sufficiently large number of cumulative cycles and substantially affects the dynamic response. Results collected in this research activity are of particular importance to validate numerical tool that aim to simulate the dynamic behaviour of systems with dry friction contacts that undergo material loss caused by wear.
Complication avoidance protocols in endoscopic pituitary adenoma surgery: a retrospective cohort study in 514 patients
Authors: Thakur Jai Deep , Corlin Alex , Mallari Regin Jay , Yawitz Samantha , Eisenberg Amalia , Sivakumar Walavan , Griffiths Chester , Carrau Ricardo L. , Rettinger Sarah , Cohan Pejman , Krauss Howard , Araque Katherine A. , Barkhoudarian Garni , Kelly Daniel F. 
Published: July 2021

Abstract
Purpose
To evaluate the impact of using consistent complication-avoidance protocols in patients undergoing endoscopic pituitary adenoma surgery including techniques for avoiding anosmia, epistaxis, carotid artery injury, hypopituitarism, cerebrospinal fluid leaks and meningitis.

Methods
All patients undergoing endoscopic adenoma resection from 2010 to 2020 were included. Primary outcomes included 90-day complication rates, gland function outcomes, reoperations, readmissions and length of stay. Secondary outcomes were extent of resection, short-term endocrine remission, vision recovery.

Results
Of 514 patients, (mean age 51 ± 16 years; 78% macroadenomas, 19% prior surgery) major complications occurred in 18(3.5%) patients, most commonly CSF leak (9, 1.7%) and meningitis (4, 0.8%). In 14 of 18 patients, complications were deemed preventable. Four (0.8%) had complications with permanent sequelae (3 before 2016): one unexplained mortality, one stroke, one oculomotor nerve palsy, one oculoparesis. There were no internal carotid artery injuries, permanent visual worsening or permanent anosmia. New hypopituitarism occurred in 23/485(4.7%). Partial or complete hypopituitarism resolution occurred in 102/193(52.8%) patients. Median LOS was 2 days; 98.3% of patients were discharged home. Comparing 18 patients with major complications versus 496 without, median LOS was 7 versus 2 days, respectively p < 0.001. Readmissions occurred in 6%(31/535), mostly for hyponatremia (18/31). Gross total resection was achieved in 214/312(69%) endocrine-inactive adenomas; biochemical remission was achieved in 148/209(71%) endocrine-active adenomas. Visual field or acuity defects improved in 126/138(91.3%) patients.

Conclusion
This study suggests that conformance to established protocols for endoscopic pituitary surgery may minimize complications, re-admissions and LOS while enhancing the likelihood of preserving gland function, although there remains opportunity for further improvements.
Reassessing the commuting penalty for immigrants: new evidence from Spain
Authors: Casado-Díaz José M. , Simón-Albert Raquel , Simón Hipólito 
Published: July 2021

AbstractThis article examines the differences in commuting length between native and immigrant employees in Spain, a relevant issue since immigrants' longer commuting times may, among other factors, reflect an imperfect spatial matching of their labour supply and demand with negative implications for their relative labour outcomes and their individual well-being. The research differentiates immigrants according to their origin and is based on a rich, nationally representative database. A novel contribution of the research is the use of decomposition econometric techniques that allow quantifying the joint and individual influence of a wide range of explanatory factors. The evidence obtained shows that, although a relevant part of the explanation of the greater commuting observed for immigrants is related to observed elements such as a different use of modes of transport, they make overall significantly longer journeys when comparing with observationally similar natives. This commuting penalty occurs yet only in the case of immigrants from emerging countries as it does not exist for those from advanced economies. Although the penalty is overall rather similar along several sociodemographic and occupational lines, it is much more pronounced for individuals living in large municipalities, which implies that previous analyses focusing on specific densely populated territories could not be nationally representative. To conclude, we offer additional novel evidence about the potential explanations of the commuting penalty of immigrants showing that it does not seem to derive from a hypothetically greater tolerance to commuting.
Vehicle scheduling for on-demand vehicle fleets in macroscopic travel demand models
Authors: Hartleb Johann , Friedrich Markus , Richter Emely 
Published: July 2021

AbstractThe planning of on-demand services requires the formation of vehicle schedules consisting of service trips and empty trips. This paper presents an algorithm for building vehicle schedules that uses time-dependent demand matrices (= service trips) as input and determines time-dependent empty trip matrices and the number of required vehicles as a result. The presented approach is intended for long-term, strategic transport planning. For this purpose, it provides planners with an estimate of vehicle fleet size and distance travelled by on-demand services. The algorithm can be applied to integer and non-integer demand matrices and is therefore particularly suitable for macroscopic travel demand models. Two case studies illustrate potential applications of the algorithm and feature that on-demand services can be considered in macroscopic travel demand models.
A deep look into radiomics
Authors: Scapicchio Camilla , Gabelloni Michela , Barucci Andrea , Cioni Dania , Saba Luca , Neri Emanuele 
Published: July 2021

AbstractRadiomics is a process that allows the extraction and analysis of quantitative data from medical images. It is an evolving field of research with many potential applications in medical imaging. The purpose of this review is to offer a deep look into radiomics, from the basis, deeply discussed from a technical point of view, through the main applications, to the challenges that have to be addressed to translate this process in clinical practice. A detailed description of the main techniques used in the various steps of radiomics workflow, which includes image acquisition, reconstruction, pre-processing, segmentation, features extraction and analysis, is here proposed, as well as an overview of the main promising results achieved in various applications, focusing on the limitations and possible solutions for clinical implementation. Only an in-depth and comprehensive description of current methods and applications can suggest the potential power of radiomics in fostering precision medicine and thus the care of patients, especially in cancer detection, diagnosis, prognosis and treatment evaluation.
SoundSight: a mobile sensory substitution device that sonifies colour, distance, and temperature
Authors: Hamilton-Fletcher Giles , Alvarez James , Obrist Marianna , Ward Jamie 
Published: July 2021

AbstractDepth, colour, and thermal images contain practical and actionable information for the blind. Conveying this information through alternative modalities such as audition creates new interaction possibilities for users as well as opportunities to study neuroplasticity. The ‘SoundSight’ App (www.SoundSight.co.uk) is a smartphone platform that allows 3D position, colour, and thermal information to directly control thousands of high-quality sounds in real-time to create completely unique and responsive soundscapes for the user. Users can select the specific sensor input and style of auditory output, which can be based on anything—tones, rainfall, speech, instruments, or even full musical tracks. Appropriate default settings for image-sonification are given by designers, but users still have a fine degree of control over the timing and selection of these sounds. Through utilising smartphone technology with a novel approach to sonification, the SoundSight App provides a cheap, widely accessible, scalable, and flexible sensory tool. In this paper we discuss common problems encountered with assistive sensory tools reaching long-term adoption, how our device seeks to address these problems, its theoretical background, its technical implementation, and finally we showcase both initial user experiences and a range of use case scenarios for scientists, artists, and the blind community.
Interaction and the end of the Late Bronze Age as displayed through neutron activation analysis of Late Helladic sherds: a case study on Asine in the Argolid, Greece
Authors: Sjöberg B. L. , Mommsen H. 
Published: July 2021

AbstractThis article discusses the results of neutron activation analysis made on a limited number of LH IIIB and LH IIIC period sherds from the Argive settlement Asine, Greece. The analysis indicates that the transformation from the palatial to the post-palatial period, on a local level of a village as Asine, was not signified by loss of contacts with the surrounding world. Rather continuity and interaction prevailed, although with other geographical areas as production and use of pottery in the LH IIIB period apparently had a more regional preponderance. The geographical dominance of pottery assigned to producers in north-eastern Peloponnese and distributed over the Mediterranean was terminated, but other operators may have responded to the demand for pottery.