bluuebunny/crossref_metadata_2025_split huggingface dataset:
Die periartikuläre Demineralisation bei rheumatoider Arthritis
Authors: Pfeil Alexander , Oelzner Peter , Hoffmann Tobias , Renz Diane M. , Wolf Gunter , Böttcher Joachim 
Published: February 2021

ZUSAMMENFASSUNGDie rheumatoide Arthritis (RA) geht aufgrund der chronischen Entzündung im Bereich der kleinen Finger- und Vorfußgelenke mit einer periartikulären Demineralisation in Nähe der Gelenkflächen einher. Eine Quantifizierung der periartikulären Demineralisation ist zuverlässig durch die Digitale Radiogrammetrie und die hochauflösende periphere quantitative Computertomografie möglich. Die chronische Entzündungs- und Krankheitsaktivität der RA ist eng mit einer periartikulären Demineralisation verbunden. Deshalb ist eine Beurteilung des Schweregrades als auch der Krankheitsaktivität der RA über die periartikuläre Demineralisation realisierbar und es können über die Bestimmung der periartikulären Demineralisation Therapieeffekte einer Basistherapie evaluiert werden.
Survey of Rejection Prophylaxis Following Suture Removal in Penetrating Keratoplasty in Germany
Authors: Heinzelmann Sonja , Böhringer Daniel , Maier Philip Christian , Seitz Berthold , Cursiefen Claus , Maier Anna-Karina B. , Dietrich-Ntoukas Tina , Geerling Gerd , Viestenz Arne , Pfeiffer Norbert , Reinhard Thomas 
Published: February 2021

AbstractBackground Penetrating keratoplasty (PK) gets more and more reserved to cases of increasing complexity. In such cases, ocular comorbidities may limit graft survival following PK. A major cause for graft failure is endothelial graft rejection. Suture removal is a known risk factor for graft rejection. Nevertheless, there is no evidence-based regimen for rejection prophylaxis following suture removal. Therefore, a survey of rejection prophylaxis was conducted at 7 German keratoplasty centres.Objective The aim of the study was documentation of the variability of medicinal aftercare following suture removal in Germany.Methods Seven German keratoplasty centres with the highest numbers for PK were selected. The centres were sent a survey consisting of half-open questions. The centres performed a mean of 140 PK in 2018. The return rate was 100%. The findings were tabulated.Results All centres perform a double-running cross-stitch suture for standard PK, as well as a treatment for rejection prophylaxis with topical steroids after suture removal. There are differences in intensity (1 – 5 times daily) and tapering (2 – 20 weeks) of the topical steroids following suture removal. Two centres additionally use systemic steroids for a few days.Discussion Rejection prophylaxis following PK is currently poorly standardised and not evidence-based. All included centres perform medical aftercare following suture removal. It is assumed that different treatment strategies show different cost-benefit ratios. In the face of the diversity, a systematic analysis is required to develop an optimised regimen for all patients.
Motion Reduction for C-Arm Computed Tomography of the Pulmonary Arteries: Image Quality of a Motion Correction Algorithm in Patients with Chronic Thromboembolic Hypertension During Balloon Pulmonary Angioplasty
Authors: Maschke Sabine , Werncke Thomas , Becker Lena Sophie , Renne Julius , Dewald Cornelia Lieselotte Angelika , Olsson Karen M. , Hoeper Marius M. , Wacker Frank K. , Meyer Bernhard C. , Hinrichs Jan B. 
Published: February 2021

Purpose To evaluate the feasibility and image quality of a motion correction algorithm for supra-selective C-arm computed tomography (CACT) of the pulmonary arteries in patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing balloon pulmonary angioplasty (BPA).
Materials & Methods CACT raw data acquired during 30 consecutive BPAs were used for image reconstruction using either standard (CACTorg) or a motion correction algorithm (CACTmc), using 400 iterations. Two readers independently evaluated 188 segmental and 564 sub-segmental contrast-enhanced pulmonary arteries in each reconstruction. The following categories were assessed: Sharpness of the vessel, motion artifacts, delineation of bronchial structures, vessel geometry, and visibility of treatable lesions. The mentioned criteria were rated from grade 1 to grade 3: grade 1: excellent quality; grade 2: good quality; grade 3: poor/seriously impaired quality. Inter-observer agreement was calculated using Cohen’s Kappa. Due to an excellent agreement, the ratings of both readers were merged. Differences in the assessed image quality criteria were evaluated using pairwise Wilcoxon signed-rank test.
Results Inter-observer agreement was excellent for all evaluated image quality criteria (κ > 0.81). For all assessed image quality criteria, the ratings on CACTorg were good but improved significantly for CACTmc to excellent for the whole vascular tree (p < 0.01). When considering segmental and sub-segmental levels individually, all image quality criteria improved significantly for CACTmc on both levels (p < 0.01). While ratings of CACTmc were constant for both levels (segmental and sub-segmental) for all criteria, the ratings of CACTorg were slightly impaired for the sub-segmental arteries.
Conclusion Motion correction for supra-selective contrast-enhanced CACT of the pulmonary arteries is feasible and improves the overall image quality.
Key Points:
Citation Format
Rapid Reviews in Zeiten von COVID-19 – Erfahrungen im Zuge des Kompetenznetzes Public Health zu COVID-19 und Vorschlag eines standardisierten Vorgehens
Authors: Seidler Andreas , Nußbaumer-Streit Barbara , Apfelbacher Christian , Zeeb Hajo ,   für die Querschnitts-AG Rapid Reviews des Kompetenznetzes Public Health zu COVID-19
Published: February 2021

Zusammenfassung
Ziel Im Zuge der COVID-19-Pandemie benötigen viele gesundheitsrelevante Fragestellungen rasche Antworten. Im Kompetenznetz Public Health zu COVID-19, das im März 2020 von Vertreter:innen mehrerer wissenschaftlicher Fachgesellschaften gegründet wurde, werden vielfach Rapid Reviews erstellt, um rasch evidenzbasierte, für politische Entscheidungsträger:innen nutzbare Antworten zu generieren. Ziel dieses Beitrags ist es, die praktischen Erfahrungen bei der Durchführung von Rapid Reviews im Rahmen des Kompetenznetzes Public Health zu reflektieren. Auf dieser Grundlage sollen Methoden zur qualitativ hochwertigen und praktikablen Durchführung von Rapid Reviews entwickelt werden, die insbesondere auch zur raschen Evidenzgenerierung auf der Grundlage von Beobachtungsstudien anwendbar sind.
Methodik Unter Nutzung des von Tricco et al. [1] vorgeschlagenen 8-schrittigen Vorgehens werden die aktuellen Herausforderungen beschrieben, die sich im Kompetenznetz Public Health zu COVID-19 bei der Durchführung von Rapid Reviews zu Public Health-bezogenen Fragen der COVID-19-Pandemie ergeben haben. Die 8 Schritte lauten: 1. Formulierung der Fragestellung, 2. Literatursuche, 3. Titel-Abstract- und Volltextsichtung, 4. Datenextraktion, 5. Risk of Bias-Bewertung, 6. Evidenzsynthese, 7. Dissemination, 8. Aktualisierung. Zudem werden Lösungsvorschläge im Expert:innenkonsens der Mitglieder (n=42 zum 28.01.2021) der Querschnitts-AG Rapid Reviews des Kompetenznetzes Public Health zu COVID-19 entwickelt.
Ergebnisse Vorgelegt und zur Diskussion gestellt wird ein standardisiertes Vorgehen, das sich eng an das Vorgehen der Cochrane Rapid Reviews Methods Group anlehnt und den besonderen Anforderungen von ätiologisch orientierten, häufig auch ökologischen Beobachtungsstudien zu COVID-19 Rechnung trägt.
Schlussfolgerungen Das vorgeschlagene Vorgehen bei der Durchführung von Rapid Reviews kann – ggf. über Fragestellungen zu COVID-19 hinaus – eine wichtige Grundlage einer evidenzbasierten Politikberatung bilden. Zur kurzfristigen Realisierung von methodisch hochwertigen Rapid Reviews zu neuen Fragestellungen sollten flexible und kurzfristig aktivierbare Förderkonzepte bereitgestellt werden. Wissenschaftliche Kooperationen bei der Durchführung von Rapid Reviews sollten ausgebaut werden, dabei sollten verstärkt methodisch hochwertige Ansätze wie bspw. prospektive Metaanalysen Anwendung finden.
Association of Assisted Reproductive Technology Treatments with Imprinting Disorders
Authors: Kopca T. , Tulay Pinar 
Published: February 2021

AbstractAssisted reproductive technology (ART) is a broad field in infertility that encompasses different types of treatments. These revolutionary treatment methods aimed to aid infertile or subfertile couples. Treatment was expanded exponentially, as 1 to 3% of the births worldwide takes place with ART procedures. However, treatment is not flawless. Gametes and embryos are exposed to different chemicals and stress through treatment, which leads to disturbance in proper embryo development and results in prenatal and congenital anomalies. When compared with in-vivo development of gametes and preimplantation embryos in mice, in-vitro conditions during ART treatments have been suggested to disturb the gene expression levels, especially imprinted genes. Therefore, ART has been suggested to be associated with increased incidences of different imprinting disorders such as Beckwith–Wiedemann syndrome, Angelman syndrome, and Silver–Russell syndrome, as proved by different case reports and studies. This literature review aims to explain the association of imprinting disorders with this revolutionary treatment procedure.
Rhinoplasty Dissection Planes (Subcutaneous, Sub-SMAS, Supra-perichondral, and Sub-perichondral) and Soft Tissues Management
Authors: Neves José Carlos , Zholtikov Vitaly , Cakir Baris , Coşkun Erhan , Arancibia-Tagle Diego 
Published: February 2021

AbstractRhinoplasty as an operation is akin to a game of chess, where every maneuver will influence the eventual outcome. Undoubtedly, more than one approach to the nasal soft tissues envelop can produce beautiful and safe results as will be described in the paper namely, the subcutaneous, sub-superficial musculoaponeurotic system, supra- and sub-perichondral planes. For different justifiable reasons surgeons have their preferences, regarding dissection planes on the tip, middle and upper thirds, and regarding the manipulation of the soft tissue layers and nasal ligaments. The concept of the nasal layers and the presence of relevant ligamentous structures and how to restore them in an anatomical fashion, will help to understand the logic behind various approaches.
Evaluation of Childhood COVID-19 Cases: A Retrospective Analysis
Authors: Akoğlu Handan A. , Bulut Muhammet , Alemdar Dilek K. , Aslan Serdar , Çelikkalkan Kıvanç , Tursun Serkan , Tekin Emine , Baba Hatice , Takır Selçuk 
Published: February 2021

AbstractObjective This study aims to evaluate the demographic, epidemiological, and clinical features of novel coronavirus disease 2019 (COVID-19) cases aged between 0 and 18 years.Methods The demographic characteristics of the patients, admission symptoms, contact and travel histories, clinical onset duration, symptoms, treatments, laboratory findings, radiological images, and polymerase chain reaction (PCR) negation times were evaluated in a retrospective manner. Thirty-eight children (19 boys and 19 girls) were included in the study.Results The mean age of the patients was 10.36 ± 5.59 years. The average admission times of the patients after the onset of the symptoms was determined as 1.84 ± 2.02 days. Thirteen (34.2%) patients were observed as asymptomatic. The most common identified symptoms were fever, cough, and fatigue (55.2, 34.2, and 13.2%, respectively). Febrile convulsions, myalgia, dizziness, and diarrhea were the least common symptoms. Also, 25-hydroxyvitamin D3 (vitamin D3) levels were low and aspartate aminotransferase (AST) values were higher in the moderate group than the mild group and the relationships were statistically significant (p = 0.044and 0.027). Ferritin levels of the patients with ground glass opacity (GGO) were found statistically and significantly higher than the patients without GGO (p = 0,031). There was more than one lobe and segment involvement in five patients, the average number of affected lobes and segments was 3.8 and 8.8, respectively. High-resolution computed tomography of the 24 patients showed that; GGO in five (20.8%), consolidation + GGO (mixed) in three (12.5%), consolidation (alone) in one, subpleural linear opacities in three (12.5%), and pavement stone opacities in one (4.2%) patient. COVID-19, which is seen less frequently in children, may pose a risk in infants and young children.Conclusion Especially high ferritin levels may present with lung involvement and low vitamin D levels may worsen the aggravation of the lung involvement. There is a great need for further research on this subject.
Diagnostic Value of Plasma Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Children with Urinary Tract Infections
Authors: Tursun Serkan , Alpcan Ayşegül , Özsoy Metin , Badem Nermin Dindar , Kandur Yaşar , Acar Banu Çelikel 
Published: February 2021

Abstract
Objective The aim of the present study was to evaluate the diagnostic value of soluble triggering receptor on myeloid cells-1 as a novel marker for diagnosis of childhood urinary tract infections (UTI).
Methods This study enrolled 30 pediatric patients diagnosed with acute febrile UTIs; 30 healthy children were included as the control group. The blood samples from the patients and healthy controls were collected for a soluble triggering receptor on myeloid cells-1 (sTREM-1) test.
Results The study group was composed of 9 males and 21 females, and the mean age of the study population was 6.6 ± 3.2 (range = 1–14) years. sTREM-1 levels were significantly higher in UTI patients than in the controls (592 ± 323 vs. 490 ± 299 pg/mL, p = 0.04). The receiver operating curve analysis revealed a cut-off value of soluble triggering receptor expressed on myeloid cells-1 of 514 ng/mL (area under the curve = 0.562). When the cut-off value was taken 514 pg/mL, soluble triggering receptor expressed on myeloid cells-1 had a sensitivity of 57% and a specificity of 50% for the diagnosis of UTI.
Conclusion The present study revealed that plasma sTREM-1 level may be elevated in UTI and may therefore serve as a useful predictive tool for the diagnosis of UTI.
Hyaluronic Acid Fillers for Midface Augmentation: A Systematic Review
Authors: Trinh Lily N. , Gupta Amar 
Published: February 2021

AbstractInjectable fillers represent one of the most requested minimally invasive treatments to rejuvenate the aging face, and its popularity is steadily rising. A vast majority of filler treatments are with hyaluronic acid (HA). The aim of this systematic review is to evaluate patient outcomes, safety profile, and administration techniques of various HA fillers for malar augmentation. A systematic review of the published literature was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and included PubMed, Embase, and Science Direct databases. Medical Subject Headings (MeSH) terms used were “cheek” OR “midface” OR “malar” and “filler” OR “hyaluronic acid” OR “Juvederm” OR “Restylane” OR “Perlane” OR “Belotero.” The initial search identified 699 articles; 256 duplicates were removed. Additional 12 studies were identified from reference lists. A total of 455 were screened by title and abstract and 387 studies were eliminated based on criteria. Also, 68 articles underwent full-text review, and 18 articles were included in the final review and involved seven different HA formulations. Men and women from many age groups were highly satisfied with their results following HA treatment for midface augmentation up to 24 months. The most common adverse events included bruising, swelling, and tenderness, and typically lasted no more than 2 weeks. Upper cheek filler injections near the zygoma should be placed in the submuscular plane while lower cheek injections should be placed in the subcutaneous tissue. HA is an attractive choice for midface augmentation due to its high patient satisfaction, long-lasting effects, and low side-effect profile. Due to the variability in technique, level of expertise, and subjective measurements across studies, one optimal regimen could not be concluded. However, midface augmentation treatment should be personalized to each patient. Additional clinical trials are required to more conclusively determine the most appropriate approach for this procedure.
Restoring Balance and Symmetry to the Aging Nose
Authors: Unadkat Samit N. , Saleh Hesham A. 
Published: February 2021

AbstractAccurate assessment of facial symmetry is a key component of successful rhinoplasty surgery but is often overlooked by both surgeon and patient. Up to three-quarters of patients with a significantly crooked nose have been found to have concurrent marked facial asymmetry. Whilst not a contraindication to rhinoplasty, provided that facial asymmetry is identified in advance and expectations realistic, the correction of nasal deformities can improve perceived facial asymmetry. In the aging face, aside from soft tissue and bony resorption that can amplify facial asymmetry, there are specific surgical challenges to the aging nose; the normal tip support mechanisms deteriorate with age giving rise to distinctive changes to the aging nose—typically tip ptosis and a hanging columella; bone quality becomes more brittle and skin overlying this area becomes thinner. There is also weakening of the external nasal valve thus causing functional impairment too. As a result, rhinoplasty techniques used in younger patients may not be suitable in the aging nose. In this article, the authors describe their experience and outline the evidence on the management of the aging patient with facial and nasal asymmetry.
Cholinerges Syndrom mit Bewusstlosigkeit bei Fliegenpilzvergiftung
Authors: Hohn H. , Schoenemann J. 
Published: February 2021

Zusammenfassung
Anamnese und klinischer Befund: Ein 41-jähriger Patient wurde in seiner Wohnung komatös aufgefunden und nach notärztlicher Versorgung mit stabilen Vitalfunktionen unter dem Verdacht auf eine Cannabisintoxikation in die Klinik aufgenommen. Der bisher gesunde Patient sei Hobbygärtner und hege eine Abneigung gegen „Chemie“. Leitsymptom war ein cholinerges Syndrom mit tiefem Koma. Wir vermuten aufgrund des klinischen Erscheinungsbildes und der Anamnese eine Intoxikation durch Pflanzeningestion.
Conceptualizing shame in Old Romanian
Authors: Stoica Gabriela 
Published: February 2021

Abstract
The chapter deals with the conceptualization of a
social-moral emotion, ruşine
[shame], in Old Romanian (16th–18th centuries).
Within an integrative theoretical and methodological framework
(combining elements of Cultural Linguistics, Textual and Cognitive
Lexical Semantics, Cultural Anthropology, Psychology and Sociology
of Emotions), I tackle the patterns of conceptualizing
shame, delineating the prototypical feature
profile, together with its contextual variation, as highlighted by
the counterpart lexicalization. The corpus data bring forward a
complex componential grid. Certain types of shame
can be outlined: (a) dysphoric prototypical shame;
(b) contiguous shame, contextually intersecting
with disrespect, dishonor or
fear; (c) religious shame,
hedonically hybrid, both euphoric and dysphoric, overlapping with
respect and fear; (d)
positive shame, socially validated and decoded
as shyness, modesty, or, in a
romantic love context, as pudor.
Innate or acquired?
Authors: Finzel Anna 
Published: February 2021

Abstract
In this chapter, some of the findings from
sociolinguistic interviews with 25 speakers of Indian English and 26
speakers of Nigerian English are presented. Emanating from a larger
research project concerned with conceptualizations of
gender, the current analysis focuses on
conceptualizations of homosexuality and makes use of the
analytical tools provided by Cultural Linguistics and Cognitive
Sociolinguistics. In particular, the notions of “cultural
conceptualizations” (e.g., Sharifian, 2011, 2017) and “cultural model” (e.g., Wolf & Polzenhagen, 2009; also cf.
Schneider, 2014) are
addressed.
At the time of data collection, discriminatory
legislation concerning homosexuality was in force in India and
Nigeria. Opinion polls likewise echoed a negative stance towards
homosexuality among the population of the two countries. This raised
the expectation that similar conceptualizations of
homosexuality might be found in Indian and Nigerian
English, both in terms of their negative connotation and of how
homosexuality would exactly be conceptualized. However,
this expectation was not fulfilled. Firstly, the acceptance among
the Indian participants to this study was generally greater.
Secondly, homosexuality was predominantly conceptualized as
an innate condition in the Indian English data, while it
was prevalently understood as an acquired condition by the
Nigerian informants. Drawing from earlier findings within the
context of the same project (Finzel, 2021; fc.), I suggest that these differences
can be explained with culture-specific models of gender
that lend their logic to conceptualizations of
homosexuality.
The impact of Pr and Nd substitution on structure, hysteresis and magnetocaloric properties of La1−x
(Pr,Nd)
x
Fe11.6Si1.4
Authors: Davarpanah Amin , Radulov Iliya , Shayanfar Navid , Maccari Fernando , Skokov Konstantin , Amaral Joao , Gutfleisch Oliver 
Published: February 2021

Abstract
In this study, a combination of induction melting and suction casting methods were used to produce a series of high-purity samples of

L

a

1
−

x

R

x

F

e

11.6

S

i

1.4

system with R = Pr and Nd for x = 0.1, 0.2, 0.3 and 0.4. The Curie temperature (

T

C

) is lowered for all the substituted compositions compared to

L
a
F

e

11.6

S

i

1.4

, while the hysteresis area shows a small increase for higher amounts of substitution element. The estimated isothermal magnetic entropy change (

Δ

S
T

) of all samples are in the same range with a maximum of 25

J
k

g

−
1

K

−
1

. The

Δ

T

a
d

, under the cyclic conditions for all compositions decreases compared to the first application of the magnetic field due to the thermal hysteresis. Applying the Bean–Rodbell model to the isothermal magnetization data, the temperature dependence of the critical field was found. Excluding the phase transition region, the model accurately describes the temperature and field dependence of magnetization above and below the magnetic transition, highlighting the magnetic moment change of the system due to the structural transformation.
A nanoscale Cu2−xSe ultrathin film deposited via atomic layer deposition and its memristive effects
Authors: Lee Kyungsub , Lee Seonghoon 
Published: February 2021

Abstract
An ultrathin film of copper selenide 50 nm thick was deposited using a home-made atomic layer deposition apparatus. Synthesized copper pivalate and bis(triethylsilyl) selenide precursors were used. The deposition rate at 160 °C was 0.48 Å per atomic layer deposition cycle. The thickness was monitored by an in situ ellipsometer and further analyzed by an atomic force microscope. The composition and structure of the film were confirmed by x-ray photoelectron spectroscopy, Raman spectroscopy, and x-ray diffraction to be Cu1.16Se. The fluorine-doped tin oxide/Cu1.16Se/tungsten wire memristor was fabricated and its memristive effect was investigated. The non-linear I–V curve and spike-timing-dependent plasticity of our Cu1.16Se memristor demonstrate that the short-term and long-term potentiation that occurs in a human brain can be mimicked by adjusting voltage-pulse intervals. A memristor is the electrical equivalent of a synapse. Our memristor has a 1 ms switching time, a 400 s retention time, Roff/on = 2, and reproducibility over 1000 cycles.