bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Prognostic Value of Myocardial Injury in COVID-19 Patients and Associated Characteristics
Authors: he jian , Zhang Bicheng , Zhou Quan , Yang Wenjing , Xu Jing , Liu Tingting , Zhang Haijun , Wu Zhiyong , Li Dong , Zhou Qing , Yan Jie , Zhang Cuizhen , Weiss Robert G. , Liu Guanshu , Teng Zhongzhao , Sirajuddin Arlene , Qian Haiyan , Zhao Shihua , Arai Andrew E. , Lu Minjie , Zhou Xiaoyang 
Published: February 2021

Abstract
Background: Since December 2019, Coronavirus disease 2019 (COVID-19) has emerged as an international pandemic. COVID-19 patients with myocardial injury might need special attention. However, understanding on this aspect remains unclear. This study aimed to illustrate clinical characteristics and the prognostic value of myocardial injury to COVID-19 patients. Methods: This retrospective, single-center study finally included 304 hospitalized COVID-19 cases confirmed by real-time RT-PCR from January 11 to March 25, 2020. Myocardial injury was determined by serum high-sensitivity troponin I (Hs-TnI). The primary endpoint was COVID-19 associated mortality. Results: Of 304 COVID-19 patients (median age, 65 years; 52.6% males), 88 patients (27.3%) died (61 patients with myocardial injury, 27 patients without myocardial injury on admission). COVID-19 patients with myocardial injury had more comorbidities (hypertension, chronic obstructive pulmonary disease, cardiovascular disease, and cerebrovascular disease); lower lymphocyte counts, higher C-reactive protein (CRP, median, 84.9 vs 28.5 mg/L, p<0.001), procalcitonin levels (median, 0.29 vs 0.06 ng/ml, p<0.001), inflammatory and immune response markers; more frequent need for noninvasive ventilation, invasive mechanical ventilation; and was associated with higher mortality incidence (hazard ratio, HR=7.02, 95% confidence interval, CI, 4.45-11.08, p<0.001) than those without myocardial injury. Myocardial injury (HR=4.55, 95% CI, 2.49-8.31, p<0.001), senior age, CRP levels, and novel coronavirus pneumonia (NCP) types on admission were independent predictors to mortality in COVID-19 patients. Conclusions: COVID patients with myocardial injury on admission is associated with more severe clinical presentation and biomarkers. Myocardial injury and higher HsTNI are both strongest independent predictors to COVID related mortality after adjusting confounding factors. In addition, senior age, CRP levels and NCP types are also associated with mortality. Trial registration: Not applicable.
Light limitation inducing overcompensatory growth of cyanobacteria and function of serine/threonine kinase (STK) genes involved
Authors: Dai Wei , Chen Gao , Bi Xiangdong , Zhong Huairong , Wang Xueying , Dong Shaojie , Lv Dong , Zhang Shulin , Zhang Dajuan , Wang Na 
Published: February 2021

Abstract
The rapid overcompensatory growth that appears when cyanobacteria are supplied with adequate resources after a period of resource deprivation might contribute to the occurrence of cyanobacterial blooms. We investigated the changing characteristics of overcompensatory growth and serine/threonine kinase (STK) genes expression of cyanobacterium Microcystis aeruginosa in response to light limitation. The results showed M. aeruginosa exhibited overcompensatory growth for 2 days after light recovery, during which the increase in growth was inversely related to light intensity. Expression of STK genes, such as spkD, was upregulated significantly at 0.5–4 h after light recovery (P &lt; 0.05). To investigate the function of STK genes in the overcompensatory growth, M. aeruginosa spkD was heterologously expressed in Synechocystis. Transgenic Synechocystis exhibited greater and longer overcompensatory growth than wild-type Synechocystis after light recovery. Relative expression levels of STK genes in transgenic Synechocystis were significantly higher than those in wild-type Synechocystis at 24 h of light recovery (P &lt; 0.05). Heterologous expression of Microcystis spkD might stimulate overcompensatory growth of Synechocystis by affecting its STK gene expression.
Signs and Types of Sports Injuries in Sports Clubs
Authors: Uspuriene Aiste Barbora , Zhiglite Vaida 
Published: February 2021

One of the most important factors influencing the quality of sports club services is the competencies of the hired staff. It is also emphasized that special attention must be paid to the competencies of coaches in the field of injury prevention. Research aim – to analyze the literature and to reveal expression and type of sports injuries in sports clubs.
Realistic High-Resolution Body Computed Tomography Image Synthesis by Using Progressive Growing Generative Adversarial Network: Visual Turing Test
Authors: Park Ho Young , Bae Hyun-Jin , Hong Gil-Sun , Kim Minjee , Yun JiHye , Park Sungwon , Chung Won Jung , Kim NamKug 
Published: February 2021

Background
Generative adversarial network (GAN)–based synthetic images can be viable solutions to current supervised deep learning challenges. However, generating highly realistic images is a prerequisite for these approaches.

Objective
The aim of this study was to investigate and validate the unsupervised synthesis of highly realistic body computed tomography (CT) images by using a progressive growing GAN (PGGAN) trained to learn the probability distribution of normal data.

Methods
We trained the PGGAN by using 11,755 body CT scans. Ten radiologists (4 radiologists with <5 years of experience [Group I], 4 radiologists with 5-10 years of experience [Group II], and 2 radiologists with >10 years of experience [Group III]) evaluated the results in a binary approach by using an independent validation set of 300 images (150 real and 150 synthetic) to judge the authenticity of each image.

Results
The mean accuracy of the 10 readers in the entire image set was higher than random guessing (1781/3000, 59.4% vs 1500/3000, 50.0%, respectively; P<.001). However, in terms of identifying synthetic images as fake, there was no significant difference in the specificity between the visual Turing test and random guessing (779/1500, 51.9% vs 750/1500, 50.0%, respectively; P=.29). The accuracy between the 3 reader groups with different experience levels was not significantly different (Group I, 696/1200, 58.0%; Group II, 726/1200, 60.5%; and Group III, 359/600, 59.8%; P=.36). Interreader agreements were poor (κ=0.11) for the entire image set. In subgroup analysis, the discrepancies between real and synthetic CT images occurred mainly in the thoracoabdominal junction and in the anatomical details.

Conclusions
The GAN can synthesize highly realistic high-resolution body CT images that are indistinguishable from real images; however, it has limitations in generating body images of the thoracoabdominal junction and lacks accuracy in the anatomical details.
SEMÁFORO DO CORAÇÃO E BINGO CARDIOVASCULAR: TECNOLOGIAS EDUCATIVAS PARA PREVENÇÃO DE DOENÇAS CARDIOVASCULARES EM IDOSOS
Authors: Oliveira Luciane Silva , Frota Kairo Cardoso da , Braga Yandra Kelline Brandão , Cardoso Maria Aparecida Fernandes , Ponte Keila Maria de Azevedo 
Published: February 2021

O objetivo do presente artigo é descrever a utilização das tecnologias educativas para prevenção do adoecimento cardiovascular em idosos: Semáforo do Coração e Bingo Cardiovascular. Trata-se de um relato de experiência, realizado em novembro de 2018, com um grupo de idosos de uma Unidade Básica de Saúde do município de Sobral-Ceará. A educação em saúde foi desenvolvida através de uma oficina prática. Participaram 15 pessoas integrantes do grupo. O momento foi organizado nas seguintes fases: integração com o grupo e apresentação; investigação acerca de seus conhecimentos sobre cardiopatias através da tecnologia “Semáforo do Coração” e orientações acerca dos hábitos para a prevenção de doenças cardiovasculares através da tecnologia “Bingo Cardiovascular”. Evidenciou-se que o uso das tecnologias educativas favoreceram o processo de comunicação entre facilitadores e participantes, pois pode-se trabalhar a temática de forma lúdica e criativa, sem a necessidade de imposições, proporcionando a ressignificação do processo de aprendizagem. A elaboração e implementação das tecnologias educativas foram relevantes por instigar a criatividade dos facilitadores e facilitar o compartilhamento de conhecimentos.
ASSOCIAÇÃO DA COGNIÇÃO COM FATORES SOCIOEDEMOGRÁFICOS E QUALIDADE DE VIDA EM CRIANÇAS PORTADORAS DE FISSURA OROFACIAL NÃO SINDRÔMICA
Authors: Cavalcanti de Lima Ergellis Victor , Gomes Salles Ândrea , Da Silva Chaves Dayse , Baia da Costa Fernanda , Sampaio Souza Aloiso , Dantas de Almeida Marques Rossana Vanessa 
Published: February 2021

Trata-se de um estudo quantitativo com 67 crianças, entre 05 e 11 anos, agrupadas da seguinte forma: A1 (portadores de fissura labiopalatina; n= 21), A2 (crianças normorreativas vinculadas a escola privada; n= 23) e A3 (crianças normorreativas vinculadas a escola pública; n=23), sendo A1 o grupo caso e A2 e A3 os grupos controles. Realizaram-se anamnese, avaliação cognitiva, verificação de prontuários, análise da qualidade de vida e avaliação da qualidade de saúde oral; com a finalidade de obter correlações. A distribuição da amostra foi semelhante a outros estudos. Em A1, a fissura transforame obteve relação numérica com a inteligência abaixo da média(n=5). O grupo A2 apresentou maiores pontuações socioeconômicas em contraponto a A1 e A3, sem relação com a cognição. No A2 o domínio da incapacidade social obteve relevância com a inteligência abaixo da média(p=0,005), o que não se observou nos demais domínios de qualidade de saúde bucal do mesmo grupo e do A1 e A2. Na qualidade de vida do A1, o domínio da autonomia apresentou números menores que o A2 e A3, sem correlação com os tipos de inteligência; com os demais domínios semelhantes a outros estudos. Logo, a cognição das crianças portadoras de fissura orofacial não sindrômica não apresentou relação significativa com qualidade de vida, qualidade de saúde oral e perfil socioeconômico. Evidencia-se, portanto, a importância do tratamento multiprofissional e o seu impacto na normatização da vida de uma criança fissurada.
Palavras chave: Fenda Labial; Qualidade de vida; Cognição; Criança.
A PRESENÇA DE COMORBIDADES PSIQUIÁTRICAS E RISCO DE SUICÍDIO EM USUÁRIOS DE SUBSTÂNCIAS PSICOATIVAS
Authors: Oliveira Eliany Nazaré , Lima Letícia Mara Cavalcante , Moreira Roberta Magda Martins , Andrade Carla Suyane Gomes , Campos Marcos Pires , Almeida Paulo César 
Published: February 2021

Objetivou-se analisar a saúde mental de usuários de substancias psicoativas tendo como parâmetro a presença de comorbidades psiquiátricas e o risco de suicídio. Trata-se de uma pesquisa com abordagem quantitativa de caráter exploratório-descritivo realizada em um Centro de Atenção Psicossocial e na Estratégia Saúde da Família de um município da 11° Regional de Saúde do Ceará (11° CRES). Foram entrevistados 51 usuários de substâncias psicoativas, no período de fevereiro a junho de 2019, mediante formulário sociodemográfico; o Self-ReportingQuestionnaire, Escala questionário sobre a saúde do paciente ou para avaliação de depressão e o Índice de Risco de Suicídio. A maioria dos usuários do sexo masculino (n=33; 64,7%), com faixa etária de 31 a 50 anos (n=24; 47,0%) e pardos (n=36; 70,6%), com transtorno mental comum (n=28; 54,9%), episódio depressivo maior (n-24; 47,1%) e risco intermediário para o suicídio (n=25; 49,0%). Estes resultados sugerem que os usuários de SPA apresentam comorbidades psiquiátricas e estão mais vulneráveis aos riscos de suicídio. Neste contexto, recomenda-se um plano de cuidado integral e multiprofissional com estratégias de monitoramento das comorbidades existentes e o risco de suicídio.
ESTIMULAÇÃO ELÉTRICA NEUROMUSCULAR NA DIÁSTASE, FLACIDEZ E TROFISMO DA MUSCULATURA ABDOMINAL: UMA REVISÃO SISTEMÁTICA
Authors: Camilo Izabela Rodrigues , Silva Pâmela da , Mata Tainara Buliani da , Peres Celeide Pinto Aguiar , Bertolini Gladson Ricardo Flor 
Published: February 2021

Objetivo: Realizar uma revisão sistemática da literatura, analisando os estudos que apontem os efeitos da eletroestimulação na diástase abdominal, flacidez e hipotrofismo da musculatura abdominal. Métodos: Para tanto, foi realizada a busca de artigos experimentais e ensaios clínicos com base nas publicações acessíveis nas bases de dados MEDLINE/PubMED, SciELO, PEDro e Google acadêmico, incluindo no estudo artigos relacionados ao tema proposto e que tinham como objetivo de estudo a influência da eletroterapia no tratamento da Diástase Abdominal (DA) e/ou flacidez da musculatura abdominal, com artigos disponíveis na integra, nos idiomas português e inglês, publicados no período de 2002 a 2017. Foram excluídos do estudo, artigos que não se encaixavam a esses critérios e que utilizassem como terapia técnicas não existentes nas práticas da Fisioterapia; por utilizarem a eletroacupuntura e que fossem revisão de literatura. As buscas foram realizadas utilizando como palavras-chaves “Diástase”, “Eletroterapia”, “Abdominal”, “Pós-parto” e “Flacidez. Resultados: a estimulação elétrica acompanhada ou não de um protocolo de exercícios físicos no uso do fortalecimento da musculatura abdominal e/ou diminuição da diástase abdominal apresentou resultados positivos. Conclusão: a utilização da Estimulação Elétrica Neuromuscular é eficaz para diminuir a diástase abdominal e flacidez e melhora a hipotrofia muscular.
Comparison of the Accuracy of WhipPredict to That of a Modified Version of the Short-Form Örebro Musculoskeletal Pain Screening Questionnaire to Predict Poor Recovery After Whiplash Injury
Authors: Sterling Michele , Ritchie Carrie , Rebbeck Trudy , Cameron Ian D. , Griffin Alex , Jagnoor Jagnoor , Nicholas Michael , Nguyen Ha , Warren Jacelle 
Published: February 2021

Objective To compare the accuracy of a whiplash-specific risk screening tool (WhipPredict) with that of the modified generic short-form Örebro Musculoskeletal Pain Screening Questionnaire (SF-ÖMPSQ) for predicting poor recovery in patients following whiplash injury. Study Design Inception cohort study. Methods Two hundred two participants with acute whiplash completed the WhipPredict and modified SF-ÖMPSQ at baseline. Poor recovery was measured at 6 and 12 months using the Neck Disability Index (greater than 10%), numeric pain-rating scale (greater than 3/10), global perceived recovery (less than +4), and inability to return to preinjury work level. Accuracy statistics were calculated to predict poor recovery. Results Seventy-one percent (n = 143) of participants completed the 6-month assessment and 56% (n = 113) completed the 12-month assessment. At baseline, agreement between the WhipPredict and modified SF-ÖMPSQ was fair (prevalence-adjusted and bias-adjusted κ = 0.26; 95% confidence interval: 0.12, 0.39). Depending on the outcome, 20% to 72% of people had not recovered at 6 months and 12% to 71% had not recovered at 12 months. At 6 and 12 months, the WhipPredict tool showed high sensitivity (88%–96%) and low specificity (all outcomes less than 31%) on all 4 separate outcomes. The modified SF-ÖMPSQ showed moderate sensitivity (67%–75%) for the Neck Disability Index, numeric pain-rating scale, and global perceived recovery, high sensitivity for return to work (81%–90%), and moderate specificity (54%–77%) for all 4 outcomes. Conclusion Both tools showed acceptable accuracy in predicting poor recovery. The WhipPredict tool is recommended to correctly identify patients who will not recover but may falsely classify those who recover well. Using the modified SF-ÖMPSQ will result in fewer patients falsely categorized as being at risk of poor recovery and may result in some people being undertreated. J Orthop Sports Phys Ther 2021;51(5):207–215. Epub 19 Feb 2021. doi:10.2519/jospt.2021.9987
Safety and Environmental Management Systems (SEMS) Audit Methodology
Authors: Williams Charlie , Chawla Om 
Published: February 2021

Abstract

Introduction
In the United States, the Bureau of Safety and Environmental Enforcement (BSEE) requires an offshore lease operator to implement a Safety and Environmental Management System (SEMS), and to have it audited at least once every 3 years to evaluate its compliance to the regulatory requirements detailed in 30 CFR 250, Subpart S.
The first round of these SEMS audits, which concluded in 2013, was executed using varying audit styles – from system audits through to compliance audits. These varying audit styles, in turn, lead to differing types output, levels of detail, format and presentation.These diverse approaches may have been due, at least in part, to disparities in the expectations of stakeholders, differing interpretations of the use of the Center for Offshore Safety's (COS) SEMS Audit Protocol tools, use of other audit protocols, the experience-level of individual auditors, and the newness of the regulation.
System audits are intended to be a holistic assessment of a system, its elements, and how the elements work together to achieve system objectives. Compliance audits, on the other hand, are intended to assess adherence to specific requirements.
This white paper proposes that both types of audits should be used in tandem to reduce risk and increase confidence that a management system, and its verification programs, is operating as designed and meeting regulatory and company requirements.
Potensi Vitamin C sebagai Feed Additive untuk Mengurangi Stress pada Ternak Puyuh
Authors: Lestariningsih Lestariningsih , Puspitasari Riska Mei , Setiawan Andi , Fernandi Fuguh 
Published: February 2021

Tingginya suhu lingkungan didaerah tropis menyebabkan ternak unggas mengalami stress panas. Stresss panas pada unggas khususnya puyuh dapat memicu timbulnya berbagai penyakit, mempengaruhi pertumbuhan dan produksi telur. Cara yang bisa dilakukan untuk mengurangi stress panas pada puyuh ialah dengan memberikan feed additive berupa vitamin C, mengingat vitamin C mengandung antioksidan yang dap at digunakan untuk meredam radikal bebas yang menyebabkan stress pada puyuh. Tujuan ditulisnya artikel ini adalah untuk mengetahui seberapa besar manfaat vitamin C sebagai feed additive untuk mengurangi stress pada ternak puyuh. Materi dan metode yang digunakan dalam penulisan artikel ini adalah kajian pustaka yang selanjutnya dianalisis menggunakan pendekatan diskriptif kualitatif. Hasil dan pembahasan berisi tentang Stress pada unggas yang ditandai dengan peningkatan tekanan darah, otot, sensitivitas saraf, gula darah dan respirasi. Ketika stress terjadi secara berkelanjutan maka tubuh akan mengaktifkan hypothalamic-pituitary-adrenal cortical system. Penggunaan antioksidan yang murah bisa dengan memanfaatkan vitamin C, tak hanya itu vitamin C juga memiliki kelebihan lain seperti vitamin C, yakni mampu mengembalikan radikal tokoferol menjadi alfa tokoferol yang stabil.
El testamento de la madre del Inca Garcilaso
Authors: Miró Quesada S. Aurelio 
Published: February 2021

En abril de 1945 tuve la singular satisfacción de encontrar en el Cuzco el testamento de Isabel Suárez, nombre cristiano y español de la Princesa incaica Chimpu Ocllo, madre del egregio historiador Inca Garcilaso de la Vega.
Tal descubrimiento ha llegado a dar, por primera vez, corporeidad a la figura elusiva y misteriosa de la madre del insigne mestizo, a la que hasta ahora sólo se podía considerar como una sombra tutelar y distante. En efecto, las únicas referencias concretas que se poseían hasta hoy eran las que proporcionaba el propio Inca en sus obras, de donde han seguido repitiéndolas todos durante trescientos cincuenta años. No había, fuera de ello, un sólo informe, una sola comprobación documental que pudiera ratificar o modificar las escasas palabras del cronista.
La tragedia sexual de Leonardo de Vinci
Authors: Palomino Arana Helí 
Published: February 2021

Tal es el título de la obra en la que Freud enfoca la personalidad psicoanalítica del gran pintor del renacimiento italiano. Si como afirma Markun "muchos hombres de genio han nacido con tendencias homosexuales" tales como Oscar Wilde, Walt, Whitman, Tchaikowski y otros, ¿por qué no había de ponerse en duda la inmortal figura, apuesta y elegante, de Leonardo de Vinci?
En efecto, Freud sin considerar la homosexualidad como un tercer sexo innato al nacimiento, sino más bien como el producto de "un íntimo enlace infantil de carácter erótico, olvidado después por el individuo, a un sujeto femenino, generalmente la madre, enlace provocado o favorecido por la excesiva ternura de la misma y apoyado después por un alejamiento del padre de la vida infantil del hijo", llega a descubrir en Leonardo una homosexualidad ideal y un tipo aproximado al neurótico obsesivo, constituyendo su actividad investigadora la "meditación.obsesiva" y sus coerciones las "meditaciones del abúlico".
Analisis Beban Kerja dan Konflik terhadap Kepuasan Kerja Karyawan
Authors: Mauraksa Azis , Danial R.Deni Muhammad , Norisanti Nor 
Published: February 2021

The purpose of this study was to determine the effect of employee workload and conflict on job satisfaction. The method used in this study uses an associative method. Data collection techniques used by researchers in research is through observation, interviews, questionnaires, documentation and library research. Data analysis techniques used are multiple correlation techniques, the coefficient of determination and multiple linear regression analysis. Based on the calculation of categorizing the percentage of data scores it is known that the workload is in high criteria. This shows the workload on Sukabumi's Neptuns Screen Printing Convection. Based on the calculation of categorizing data, it is found that the value of the conflict criteria is. This means that conflicts that occur within the company Neptuns Screen Printing Studio can still be resolved. Conclusion, there is a significant influence between workload and conflict on employee job satisfaction
Keywords: Workload, Conflict, Job Satisfaction
Analisis Efektivitas Perusahaan dengan Model Du Pont System
Authors: Ramadhan Bagja Pasca , Samsudin Acep , Jhoansyah Dicky 
Published: February 2021

This study aims to determine the Du Pont System model in analyzing the effectiveness of the company's operations in generating profits at PT. Gajah Tunggal Tbk. This study uses quantitative descriptive analysis techniques that are used to describe in measuring the effectiveness of the company after carrying out calculations with the figures that have been included in the components or formulas contained in the Du Pont System model that is the Profitability Ratio consisting of Net Profit Margins (Net Profit Margin) and Return on Investment (Return On Investment), then Activity Ratio which consists of Total Asset Turnover. Conclusion, the effectiveness of the company for five years is considered not good seeing the decline that occurred in several aspects that could affect the final value of the Du Pont System.
Keywords: Company Effectiveness, Du Pont System
Pengaruh Kompensasi dan Disiplin Kerja terhadap Kinerja Karyawan
Authors: Yulandri Yulandri , Onsardi Onsardi 
Published: February 2021

The purpose of this research is to study compensation and work discipline on employee performance at PT (SBS) Sinar Bengkulu Selatan. The research method in this study uses quantitative research methods. The results of the study can be concluded regarding the respondents' perceptions about Compensation Location (X1) and Work Discipline (X2) Employee Performance results (Y) with the results of multiple linear regression obtained the following research results: Y = 14.876 + 0.277X1 + 0.795X2 analysis of responses R = 0.823 ( X1) -Y), 0.926 (X2-Y) and the coefficient of determination R2 = 0.521 or approximately (52.51%) through testing the hypotheses together (simultaneously) and individuals (partial) in this study using the f test and t test, compensation (X1) and work discipline (X2), = 0,000. Conclusion, significant significant contribution and work discipline to employees at PT (SBS) Sinar Bengkulu Selatan.
Keywords: Work Discipline, Employee Performance, Compensation