bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endoscopic band ligation in the treatment of gastric antral vascular ectasia: a systematic review and meta-analysis
Authors: McCarty Thomas R. , Hathorn Kelly E. , Chan Walter W. , Jajoo Kunal 
Published: June 2021

Abstract
Background and study aims While argon plasma coagulation (APC) is the first-line treatment for gastric antral vascular ectasia (GAVE), endoscopic band ligation (EBL) has shown promising results. The aim of this study was to perform a systematic review and meta-analysis to evaluate the effectiveness of EBL for the treatment of GAVE.
Methods Individualized search strategies were developed in accordance with PRISMA and MOOSE guidelines through September 1, 2020. Measured outcomes included endoscopic success (defined as GAVE eradication/improvement), change in hemoglobin, transfusion dependency, number of treatment sessions, adverse events, rebleeding, and bleeding-associated mortality. Outcomes were compared among studies evaluating EBL versus APC.
Results Eleven studies (n = 393; 59.39 % female; mean age 58.65 ± 8.85 years) were included. Endoscopic success was achieved in 87.84 % [(95 % CI, 80.25 to 92.78); I2 = 11.96 %] with a mean number of 2.50 ± 0.49 treatment sessions and average of 12.40 ± 3.82 bands applied. For 8 studies comparing EBL (n = 143) versus APC (n = 174), there was no difference in baseline patient characteristics. However, endoscopic success was significantly higher for EBL [OR 6.04 (95 % CI 1.97 to 18.56; P = 0.002], requiring fewer treatment sessions (2.56 ± 0.81 versus 3.78 ± 1.17; P < 0.001). EBL was also associated with a greater increase in post-procedure hemoglobin [mean difference 0.35 (95 % CI 0.07 to 0.62; P = 0.0140], greater reduction in transfusions required [mean difference –1.46 (95 % CI –2.80 to –0.12; P = 0.033], and fewer rebleeding events [OR 0.11 (95 % CI, 0.04 to 0.36); P < 0.001]. There was no difference in adverse events or bleeding-associated mortality (P > 0.050).
Conclusions EBL appears to be safe and effective for treatment of GAVE, with improved outcomes when compared to APC.
Effect of Adrenocorticotropic Hormone Stimulation During Simultaneous
Bilateral Adrenal Vein Sampling in Primary Aldosteronism
Authors: Liu Wei , Zhang Jingjing , Yang Yaling , Jin Yinxin , Li Zaizhao , You Liting , Luo Jianguang , Su Xin 
Published: June 2021

AbstractThe aim of the study was to investigate the significance and influence of
adrenocorticotropic hormone (ACTH) stimulation in primary aldosteronism (PA)
patients with simultaneous bilateral adrenal vein sampling (AVS). All patients
diagnosed with PA underwent simultaneous bilateral AVS with ACTH. In 95
patients, the post-ACTH SI significantly increased (p<0.001), and it
gradually decreased from t10–t30 after ACTH stimulation
(p<0.001). The unsuccessful catheterization decreased after ACTH
stimulation. Time points within 20 min after ACTH stimulation were better for
sampling, and the selectivity did not increase over longer periods. According to
lateralization before and after ACTH stimulation, the patients could be divided
into 3 groups (U, unilateral; B, bilateral): U/U , U/B or
B/U, and B/B. Compared with the U/U group, in the
U/B or B/U and B/B groups, the lateralization index (LI)
was lower both at baseline and after ACTH stimulation (p<0.0001), the
contralateral index (CLI) was higher after ACTH stimulation (p<0.003),
the serum potassium level was higher (p<0.001), and the carbon dioxide
combining power (CO2CP) and base excess (BE) levels were lower. In conclusion,
in simultaneous bilateral AVS, ACTH stimulation had significant effects on
increasing the catheterization selectivity. Lateralization change was observed
after stimulation. After ACTH stimulation, fewer patients could be diagnosed
with lateralized PA. Patients with consistent lateralized PA showed a more
serious phenotype.
A GLP-1 Receptor Agonist Inhibits Aldosterone Release in Healthy
Volunteers
Authors: Sedman Tuuli , Volke Vallo , Heinla Keiu , Vasar Eero 
Published: June 2021

AbstractGlucagon-like peptide 1 receptor agonists (GLP-1 RAs) are antidiabetic drugs with
effects beyond antihyperglycemic action. The aim of the study was to examine
whether a single dose of exenatide could be used as a stimulation test for the
pituitary-adrenal axis. We carried out a single-group, open-label pilot clinical
trial in an ambulatory setting. Ten healthy volunteers of both sexes with body
weight>65 kg and age between 18–50 years were recruited.
After fasting for 12 hours the subjects received 10 μg of
exenatide solution subcutaneously. Blood samples were taken before the
administration of exenatide and up to 150 minutes thereafter. The primary
outcome was the maximal level of cortisol after the administration of exenatide.
Single administration of exenatide 10 μg resulted in a modest
increase in ACTH and cortisol levels, as compared to untreated values, and a
decrease in blood glucose levels. Remarkably, a robust suppression of both renin
and aldosterone levels occurred. We showed that acute administration of
exenatide in a full therapeutic dose modestly stimulates the
hypothalamic-pituitary-adrenal axis but inhibits the renin-aldosterone system.
Further research is warranted to confirm this finding in the placebo-controlled
study.
Recent Applications of the Diels–Alder Reaction in the Synthesis of Natural Products (2017–2020)
Authors: Sara Alexandru A. , Um-e-Farwa Um-e-Farwa , Saeed Aamer , Kalesse Markus 
Published: June 2021

AbstractThe Diels–Alder reaction has long been established as an extremely useful procedure in the toolbox of natural product chemists. It tolerates a wide spectrum of building blocks of different complexity and degrees of derivatization, and enables the formation of six-membered rings with well-defined stereochemistry. In recent years, many total syntheses of natural products have been reported that rely, at some point, on the use of a [4+2]-cycloaddition step. Among classic approaches, several modifications of the Diels–Alder reaction, such as hetero-Diels–Alder reactions, dehydro-Diels–Alder reactions and domino-Diels–Alder reactions, have been employed to extend the scope of this process in the synthesis of natural products. Our short review covers applications of the Diels–Alder reaction in natural product syntheses between 2017 and 2020, as well as selected methodologies which are inspired by, or that can be used to access natural products.1	Introduction2	Syntheses from 20173	Syntheses from 20184	Syntheses from 20195	Syntheses from 20206	Conclusion
Cardiovascular Oncology: The Need for a Multidisciplinary Approach
Authors: Ortega Pérez Rodrigo , Pardo Sanz Ana , García Gutiérrez Valentín , Zamorano Gómez José Luis 
Published: June 2021

AbstractImproved cancer survivorship has led to an increase in cardiovascular (CV) complications in the oncologic population, mainly associated with therapeutic regimens. Hence, cardio-oncology has grown toward unifying the cancer care process in which the best prevention, early detection, treatment, and CV surveillance are offered to patients. This multidisciplinary approach allows us to optimize and agree upon clinical decisions to enhance clinical outcomes. Atrial fibrillation is one of the hot topics in the field because it is still challenging in cancer patients. The optimal antithrombotic therapy remains unclear. Nevertheless, evidence supports that specific recommendations are needed due to a hemorrhagic/thrombotic disbalance present within this subgroup of patients and a low rate of anticoagulation treatments compared with the general population. Further, cardiotoxicity management is currently transforming. Increasingly, early detection of subclinical alterations is raising awareness. When medical therapy is initiated early, fewer patients progress to ventricular dysfunction and the rate of patients completing cancer therapy gradually increases. New approaches are demonstrating better outcomes and these strategies will expectedly be established in clinical practice. Cardio-oncology enables us to find the best balance between cancer treatment and CV health protection. Nowadays, more and more physicians are being instructed in this discipline, which gradually exhibits a greater presence in conferences and scientific journals. However, given the need for physicians thoroughly trained in cardio-oncology, this subspecialty must be promoted further.
Impact of the channel length on molybdenum disulfide field effect transistors with hafnia-based high-k dielectric gate
Authors: Sun Yanxiao , Niu Gang , Ren Wei , Zhao Jinyan , Wang Yankun , Wu Heping , Jiang Luyue , Dai Liyan , Xie Ya-Hong , Rojo Romeo Pedro , Bouaziz Jordan , Vilquin Bertrand 
Published: June 2021

Field effect transistors (FETs) using two-dimensional molybdenum disulfide (MoS2) as the channel material has been considered one of the most potential candidates for future complementary metal-oxide-semiconductor technology with low power consumption. However, the understanding of the correlation between the device performance and material properties, particularly for devices with scaling-down channel lengths, is still insufficient. We report in this paper back-gate FETs with chemical-vapor-deposition grown and transferred MoS2 and Zr doped HfO2 ((Hf,Zr)O2, HZO) high-k dielectric gates with channel lengths ranging from 10 to 30 µm with a step of 5 µm. It has been demonstrated that channels with the length to width ratio of 0.2 lead to the most superior performance of the FETs. The MoS2/HZO hybrid FETs show a stable threshold voltage of ∼1.5 V, current on/off ratio of &gt;104, and field effect mobility in excess of 0.38 cm2 V−1 s−1. The impact of the channel lengths on FET performance is analyzed and discussed in depth. A hysteresis loop has been observed in the Ids − Vgs characteristics of the hybrid FETs, which has been further studied and attributed to the charge effect at the interfaces. The HZO films show a relatively weak ferroelectric orthorhombic phase and thus serve mainly as the high-k dielectric gate. Charge trapping in the HZO layer that might induce hysteresis has been discussed. Our results show that MoS2/HZO hybrid FETs possess great potential in future low power and high-speed integrated circuits, and future work will focus on further improvement of the transistor performances using ferroelectric HZO films and the study of devices with even shorter MoS2 channels.
Water calorimetry-based k

Q
factors for Farmer-type ionization chambers in the SOBP of a carbon-ion beam
Authors: Holm Kim Marina , Jäkel Oliver , Krauss Achim 
Published: June 2021

Abstract
The dosimetry of carbon-ion beams based on calibrated ionization chambers (ICs) still shows a significantly higher uncertainty compared to high-energy photon beams, a fact influenced mainly by the uncertainty of the correction factor for the beam quality k

Q
. Due to a lack of experimental data, k

Q
factors in carbon-ion beams used today are based on theoretical calculations whose standard uncertainty is three times higher than that of photon beams. To reduce their uncertainty, in this work, k

Q
factors for two ICs were determined experimentally by means of water calorimetry for the spread-out Bragg peak of a carbon-ion beam, these factors are presented here for the first time. To this end, the absorbed dose to water in the 12C-SOBP is measured using the water calorimeter developed at Physikalisch-Technische Bundesanstalt, allowing a direct calibration of the ICs used (PTW 30013 and IBA FC65G) and thereby an experimental determination of the chamber-specific k

Q
factors. Based on a detailed characterization of the irradiation field, correction factors for several effects that influence calorimetric and ionometric measurements were determined. Their contribution to an overall uncertainty budget of the final k

Q
factors was determined, leading to a standard uncertainty for k

Q
of 0.69%, which means a reduction by a factor of three compared to the theoretically calculated values. The experimentally determined values were expressed in accordance with TRS-398 and DIN 6801-1 and compared to the values given there. A maximum deviation of 2.3% was found between the experiment and the literature.
Study of Customer Satisfaction on Construction Company Performance in the Scope of Public Works Office in Ternate City
Authors: Ahadian ER , Rizal M , Albaar N 
Published: June 2021

Abstract
The construction business world is a world of competition, whose intensity is getting tougher from day to day. One of the factors causing low loyalty is the lack of customer satisfaction with products and services so far. This study aims to determine what factors influence satisfaction (Owner) of the performance of construction companies (Contractors) that are within the scope of the Ternate City Public Works Department. Based on the analysis of the Weigh Mean Method used to measure the performance of contractor companies in Ternate City. The results of the analysis at the level of satisfaction with the highest mean value is 3.5641, namely (K3 and K11), namely the Quality of the Bag in Accordance with Technical Specification and the Conformity of the Project Report to Actual Conditions in the Field.
Skin Cancer Classification Detection using CNN and SVM
Authors: Pushpalatha A , Dharani P , Dharini R , Gowsalya J 
Published: June 2021

Abstract
Skin malignant growth is quite possibly the most commonly seen Malignancy type in people. Skin disease happens because of the un controllable developing of transformations occurring in DNAs developing to certain reasons. Perceiving the malignant growth in beginning phases could build the opportunity of an effective treatment. These days, PC helped finding applications are utilized nearly at each field. From the real dermo scopic images, the first-stage network aims for precise segmentation of the skin lesion. The second-stage network is a classification network that can predict the existence of Melanoma and Squamous Cell Carcinoma in a skin sample. Deep convolutional neural networks, such as Inception-v4, ResNet-152, and DenseNet-161, were trained for melanoma and squamous cell carcinoma detection and seborrheickeratosis classification. U-Net with VGG-16 Encoder was trained to create segmentation masks for lesion segmentation. Resnet engineering achieves the highest precision of 90 percent among the equations used in the proposed models.
Development and testing of low-power EP based on the ablative pulsed plasma thruster for an ERS SSC
Authors: Bogatyi A V , Dyakonov G A , Kashirin D A , Popov G A , Semenikhin S A 
Published: June 2021

Abstract
The paper presents the appearance of a low-power electric propulsion system for a small remote sensing satellites based on an ablative pulsed plasma thruster. Preliminary analysis for the purpose and fields of application of ablative pulsed plasma thrusters (APPT) was carried out. The design appearance of a thruster for small remote sensing satellites was identified, and the main directions of APPT further development were defined. Methods for calculating the APPT propulsion characteristics were developed. The breadboard model of APPT for small remote sensing satellites was developed and made (APPT-350). Research tests of the breadboard model of APPT for Earth remote sensing small spacecrafts were carried out.
Mathematical modeling of safe payload separation using logos software on chimera-type grids
Authors: Sokuler M S , Arifullin R KH 
Published: June 2021

Abstract
One of the most important problems in the development of air weapons is the separation of air weapons from the aircraft. Carrying out this type of tests is expensive, time-consuming and dangerous, so separation and prediction of the trajectory of air weapons using numerical simulation becomes an important part of the study. In this work, a full-scale model of F-18 and a full-scale model of air weapons GBU-31 JDAM were used to test the planned trajectory of separation of air weapons from the wing. The transonic flight mode with Mach number M = 0.962 was considered. The Navier-Stokes and Euler equations were used for numerical modeling, considering the effect of the fluid viscosity effect on the flight path of air weapons during separation from the wing.
Nonlinear stability analysis of a collinear libration point in the planar circular restricted photogravitational three-body problem
Authors: Bardin B S , Avdyushkin A N 
Published: June 2021

Abstract
We investigate the problem on stability of collinear libration point in the photogravitational three-body problem. That is, we study the stability of stationary motion of an infinitesimal small body (particle) in gravitational field of two bodies (primaries) acting on the particle with radiation pressure repulsive forces. The primaries move in circular coplanar orbits about their barycenter and the particle lies in the plane of primaries motion. By using the method of normal forms and applying theorems of the Kolmogorov-Arnold-Moser theory we perform nonlinear stability study of collinear point, which located on the line connecting the primaries. Rigorous conclusions on stability in the sense of Lyapunov have been obtained both for non-resonant case and for cases of third and fourth order resonances. These results can be interesting for spaceflight and astronomical applications such as studies of dynamics of artificial satellites and observations of cosmic dust.
Analysis of the latent space of pre-trained deep convolutional neural networks in the problem of automatic segmentation of color images
Authors: Galkin V , Makarenko A , Targamadze D 
Published: June 2021

Abstract
The paper presents a primary study of the latent space structure of neural networks trained for semantic segmentation. Segmentation was performed in a controlled environment of three classes of colored rectangular shapes. The classic autoencoder and U-net like architectures were chosen as reference architectures. To study the structure of the space, a combination of a perceptron that linearly separates classes and the compression algorithms UMAP and PCA was used. As a result, a tool was obtained for evaluating the quality of a neural network based on the degree of separability of classes in the latent space of the network.
Simulation of non-stationary gas dynamics of solid propellant rockets launch
Authors: Kostyushin K V , Kagenov A M , Eremin I V , Zhiltsov K N , Chervakova A V 
Published: June 2021

Abstract
The article presents the results of the development of methodology for the calculation of non-stationary gas dynamics processes occurring in gas dynamic paths of rocket engines and environment at the launch of rockets. The method takes into account the change of geometry of solid fuel combustion surface during the operation of the engine and the change in the geometry of the computational domain taking into account the dynamics of rocket launch. Numerical simulation of gas-dynamic processes of the launch of model solid-fuel rocket was done. The unsteady gas-dynamic flow pattern was investigated. The pressure curve in the solid propellant rocket engine combustion chamber, the speed of movement and overload were determined.
Development of an unmanned aerial vehicle to study atmospheric boundary-layer turbulent structure
Authors: Chechin D G , Yu Artamonov A , Ye Bodunkov N , Yu Kalyagin M , Shevchenko A M , Zhivoglotov D N 
Published: June 2021

Abstract
One of the main challenges in the boundary-layer turbulence research consists in advancing turbulence theory towards describing turbulent regimes over inhomogeneous and irregular surface which is often the case in nature. Novel observational techniques are required to sample turbulence statistics in such conditions. To that aim, a light-weight payload for atmospheric turbulence measurements is designed and used on a vertical take-off and landing (VTOL) fixed-wing unmanned aerial vehicle (UAV). Such an observational platform complements traditional mast observations and makes it possible to sample turbulence statistics over remote and inhomogeneous landscapes. The advantages of the VTOL scheme consist in: i) minimizing the risk of the payload damage during landing; ii) less strict requirements to the surface conditions in the landing area. The turbulence payload consists of a miniature seven-hole probe, inertial navigation system and a fine-wire resistance thermometer. The seven-hole probe and the fine-wire temperature sensor were designed and calibrated as part of this study. In addition, the payload also includes a slow-response temperature-humidity sensor, relatively fast humidity sensor as well as an infrared surface temperature sensor. For the onboard data-logging, a computer based on Raspberry Pi 4 is used. The whole system has been successfully tested at the Tsimlyansk research station, Russia.
Elastic computing self-organizing for artificial intelligence space exploration
Authors: Semenov A 
Published: June 2021

Abstract
The aim of this article is to provide a methodology useful for designing and controlling elastic computing self-organizing for artificial intelligence space exploration. The artificial intelligence application itself should be elastic and distributed in the context of limited information technologies resources in space. The most important use of elastic computing is artificial intelligence’s ability to continually learn and adapt to evolving environments and goals. The conceptual framework uses elastic infrastructure model and the terminology of graph dynamical systems to be able to capture a broad variety of processes taking place on self-organizing networks. The methodology’s uniqueness lies in the theory of graph dynamical systems used to explain the self-organizing processes life cycle.
Massively parallel solution of the Lambert problem
Authors: Kravchenko V S , Ivanyukhin A V 
Published: June 2021

AbstractThis paper considers the possibility of massively parallel solution to the Lambert problem on graphics processing units. Several of the most popular solution algorithms were used for this problem. Software implementation of algorithms under consideration has been developed using Compute Unified Device Architecture technology that allows performing calculations on graphics processing units. A distinctive feature of this project is an attempt to use parallel programming within an iterative scheme. The developed algorithms have been tested on a number of typical tasks: contouring of Earth – Mars direct flight isolines and solution of the problem of a flight to a group of asteroids for the given start date and flight duration. For such tasks we give estimates of execution time and paralleling efficiency.
Self-electromagnetic emission from a thruster with anode layer operating with krypton and xenon
Authors: Shilov S , Ivakhnenko S , Vorob’ev E , Manegin D , Plokhikh A , Vazhenin N , Merkurev D , Zakharchenko V 
Published: June 2021

Abstract
This paper considers the study of self electromagnetic emission from the experimental model of low-power thruster with anode layer (TAL) developed by the Bauman Moscow State Technical University. The measurements were carried out during the thruster operation on krypton and xenon for three operating modes: 600 W, 800 W and 1000 W at a discharge voltage of 300 V. Parameters of the generated electromagnetic fields were measured in frequency range from 1 GHz to 12 GHz in the filter bandwidth of 1 MHz. The receiving antenna was installed at a distance of 1 m from the thruster exit plane, perpendicularly to its axis. The results of analysis and comparison of TAL emission spectral characteristics during its operation on krypton and xenon are presented.