bluuebunny/crossref_metadata_2025_split huggingface dataset:
Generation of Hydrogeological Units for 3D Modelling Using Open‐Source Tools in the Mexico Basin
Authors: Montaño‐Caro Juan Camilo , Escolero‐Fuentes Oscar , Morales‐Casique Eric 
Published: February 2025

ABSTRACTThis dataset contains hydrogeological cross‐sections for 3D modelling in the Mexico Basin, developed using Python scripts and GIS tools. The cross‐sections are based on existing geological studies and integrate a variety of lithologies and structural features, including volcanic and sedimentary units. While the dataset provides comprehensive coverage, it does acknowledge limitations in geological and structural resolution due to the availability of data. The dataset includes shapefiles representing hydrogeological units in both line and polygon formats, alongside topographic sections, surface hydrogeological distribution and regional fault systems. Although modifications may be required for specific applications, it serves as a strong foundation for multidisciplinary studies in groundwater and geological modelling. Hosted on open‐source repositories, the data can be easily adapted for use in 3D modelling frameworks like GemPy and FloPy. This dataset is a valuable resource for understanding groundwater dynamics in the Mexico Basin and offers flexibility for future updates as new data become available or project needs evolve.
Elucidation of Potable Water Accelerated Weathering of Limestone for Post‐Combustion Carbon Capture: Correlation, Optimization, Comparative, Kinetic Modelling and Mass Transfer Analysis
Authors: Chai Slyvester Yew Wang , How Bing Shen , Ngu Lock Hei 
Published: February 2025

ABSTRACTEnergy generation and industrial processes are the main emitters of CO2, with 37.4 billion tCO2 in 2023, causing detrimental environmental effects. As absorption is the most established carbon capture technology, this research implements the accelerated weathering of limestone (AWL) process to capture CO2 from post‐combustion emissions. However, this work replaces the conventional water source for the AWL process, seawater, with potable water. A correlation study was performed to study the effect of the proposed process's liquid‐to‐gas (L/G) ratio on the performance (i.e., effluent's alkalinity and CO2 capture efficiency). The correlation findings show that by decreasing the L/G ratio (1–0.003), the calcium bicarbonate (Ca(HCO3)2) effluent concentration (0.77–3.65 mM) and pH (5.58–7.47) increase significantly, whereas CO2 capture efficiency (81.94%–20.82%) was adversely affected. The optimization analysis obtained the highest achievable alkalinity at 3.63 mM at an optimized liquid and gas flow rate of 0.024 and 10 L min−1, respectively. Meanwhile, the liquid and gas flow rates of 1.23 and 1 L min−1 achieved the highest CO2 capture efficiency of 82.15%. It was deduced that potable water is better than seawater for CO2 capture operation via the AWL process, achieving a 12.09%–39.14% better CO2 capture efficiency when operated at similar conditions. In addition, the kinetic and mass transfer performance of the proposed process was also established in this work. Overall, this research establishes the potential of a potable water‐operated AWL process for future commercialization.
Assessment Improvement of Heat Performance and Hydraulic Thermal Flow in a Three‐Dimensional Tube Equipped With Different Turbulator Corrugated Arrangements
Authors: Al‐Haidari Saad Raad , Al‐Obaidi Ahmed Ramadhan 
Published: February 2025

ABSTRACTCorrugated pipe is used in many engineering applications because of its high performance compared with smooth pipe. This research involved numerical simulations and experimental testing of a circular tube with a modified flow path to improve the heat transfer performance of heat exchangers. The focus was on enhancing mixing and creating vortex flows within the tube to increase heat exchange efficiency. The impact of seven design factors, including ring diameters (RD) and the pitch between ring pitches (RP), on thermal–hydraulic performance was investigated. Water is used as the working fluid and the flow regime ranges from 4000 to 15,000, indicating turbulent flow. A constant heat flux of 25,500 W/m2 is applied, and the water enters the system at a temperature of 298 K (25°C). The properties of water are assumed to remain constant throughout the flow with flow conditions, such as a steady state (the flow conditions do not change with time), incompressible flow (the density of the fluid remains constant), and no‐slip condition (the fluid velocity at the surface of any solid boundary is zero). Corrugated tubes consistently outperformed smooth tubes in heat transfer due to increased flow mixing and separation. Both increasing the Reynolds number and decreasing the design factors led to the formation of mixing and vortex patterns. In RD configurations, the Nusselt number saw an average improvement of approximately 45.6%, while the friction factor increased between 19% and 57%. RP configurations demonstrated a broader range of Nusselt number enhancements, reaching up to 35%, and friction factor increases ranging from 15% to 42%. Rings can significantly enhance the thermal–hydraulic performance of tubes. However, the best configuration depends on the specific application. The configuration with the highest performance, resulting in a 1.38 increase in performance evaluation factor, was obtained using an RD of 1 mm and an RP of 20 mm. The simulated and experimental data showed excellent agreement, with a maximum discrepancy of less than 11% for both smooth and dimpled tubes.
Developing a Two‐Dimensional Semi‐Analytical Solution on a Plan View for a Consecutive Divergent Tracer Test Considering Regional Groundwater Flow
Authors: Suk Heejun , Piao Jize , Liang Ching‐Ping , Han Weon Shik , Ahn Hongil , Chen Jui‐Sheng 
Published: February 2025

ABSTRACTMultiple successive tracer tests are often conducted to obtain reliable breakthrough curve results under regional groundwater flow, especially when the accuracy is crucial. In such cases, the period of rest between the end of the first divergent tracer test and the initiation of the second divergent tracer test allows the tracer from the first test to travel along with the background regional flow, thereby influencing the distribution of residual tracer concentration. This residual tracer could potentially interfere with breakthrough curve results from the tracer injection in the second tracer test. Additionally, the conventional analytical solution used for the divergent tracer test considers only radial flow; regional flow and consecutive tracer tests are ignored. Consequently, interpreting the behaviour of the tracer in consecutive divergent tracer tests under regional flow conditions is challenging using conventional measures because of background regional concentration. This study proposes a new semi‐analytical solution, considering the effects of divergent radial and regional flows in consecutive tracer tests, addressing a critical gap in the conventional analytical solutions that, despite their practical necessity, have not been previously developed. The proposed semi‐analytical solution was subjected to parameter studies under various scenarios. In our case studies, the conventional analytical solution based on a single tracer test can be safely used for parameter estimation only in cases where the injected mass for the subsequent tracer test is approximately six‐fold that of the first tracer test or if the drift time is longer than 10 days.
Methods Used to Assess Early Mathematical Skills in 2‐Year‐Olds: A Review of the Literature
Authors: Weiers Hanna , Ghattaura Sohnia , Scerif Gaia , Sella Francesco , Simms Victoria , Xenidou‐Dervou Iro , Gilmore Camilla 
Published: February 2025

ABSTRACTWhen children are aged around 2 years, many of the early foundations of mathematical skills are developing. Understanding this is important to shed light on theories of mathematical development. Nevertheless, little research has investigated 2‐year‐olds' early mathematical abilities, with most research focussing on either infants (aged 0–1 years) or pre‐schoolers (aged 3–5 years). One possible reason for this lack of research may be the challenges associated with the methods used with this age group. Here, we review the methods used to assess 2‐year‐olds' basic mathematical skills and identify the gaps and issues with those methods. Our findings indicate several issues, both with individual methods used to test specific skills but also some common challenges applicable across all measures and skills. We discuss the identified issues and highlight a need for more appropriate approaches and for alternative methods of administration to better evaluate 2‐year‐olds' mathematical skills.
Factors affecting the success of labor in twin pregnancies: A retrospective study on maternal and fetal outcomes
Authors: Zhang Hong , Gao Tianhong , Du Hui 
Published: February 2025

AbstractObjectiveTo explore the relevant factors associated with successful labor in twin pregnancies and investigate maternal and fetal outcomes in the group with failed labor.MethodsA retrospective analysis was conducted on twin pregnancies that underwent labor in our hospital from July 2016 to June 2023. A total of 519 cases were divided into two groups: the successful labor group (450 cases with vaginal delivery of both fetuses) and the failed labor group (69 cases with cesarean delivery of one or two fetuses). The relevant factors of the labor, as well as the maternal and fetal outcomes, were analyzed between these two groups.ResultsMultivariate analysis indicated that advanced maternal age (odds ratio [OR] 1.13, 95% confidence interval [CI] 1.05–1.22), high pre‐delivery body mass index (OR 1.11, 95% CI 1.04–1.19), and vertex/transverse twins (OR 3.75, 95% CI 1.35–10.40) were risk factors for the failure of vaginal labor. Multiparity (OR 0.15, 95% CI 0.08–0.29), premature birth (OR 0.43, 95% CI 0.24–0.78), and neuraxial analgesia (OR 0.37, 95% CI 0.20–0.72) were protective factors for the failure of delivery. There were no statistically significant differences (P > 0.05) in decreased hemoglobin and neonatal outcomes between the two groups. The postpartum hospitalization time in the successful labor group was shorter than that in the failed labor group (P < 0.05).ConclusionsLabor in twin pregnancies is generally safe. Factors such as multiparity, previous premature birth, and neuraxial analgesia can significantly enhance the likelihood of a successful vaginal delivery.
Cover Image
Authors: Lee Dae Kyu , Noh Gichang , Oh Seungmin , Jo Yooyeon , Park Eunpyo , Kim Min Jee , Woo Dong Yeon , Wi Heerak , Jeong YeonJoo , Jang Hyun Jae , Kim Sangbum , Lee Suyoun , Kang Kibum , Kwak Joon Young 
Published: February 2025

A crystallinity‐controlled ZrO2‐based memristor with localized conductive filaments along low energy pathways is proposed as a short‐term memory for reservoir computing.
image
Structure–function relationships between the human bitter taste receptor TAS2R38 and propylthiouracil: An in‐silico investigation
Authors: Subramanian Gowtham , Ponnusamy Vinithra , Murugesan Janaranjani , Vedagiri Hemamalini , Panneerselvan Prabha , Vasanthakumar Keerthana , Krishnan Vasanth , Subramaniam Selvakumar 
Published: February 2025

AbstractTaster categorisation uses bitter thiourea compounds like propylthiouracil (PROP) and phenylthiocarbamide (PTC), which are frequently associated with amino acid alterations at positions 49, 262 and 296 in human taste 2 receptor member 38 (hTAS2R38). Since the hTAS2R38 protein lacked a crystallographic structure, it was modelled using contact‐guided iterative threading assembly refinement, its residues were mutated and refined, and the binding pocket area and volume were assessed using CASTp. Bitter thiourea molecules were docked using the ligand extra precision module and the receptor–ligand complex was manually positioned in a fully hydrated, equilibrated 1‐palmitoyl‐2‐oleoylphosphatidylcholine bilayer using the CHARMM GUI membrane constructor, a 100 ns simulation was carried out using the Desmond program. Analysis revealed that the PROP binds to the allosteric hydrophobic pocket of hTAS2R38 and forms a hydrogen bond with ASN190. The native structure (hTAS2R38PAV) has a higher glide energy (−24.164 kcal/mol) and docking score (−7.212 kcal/mol) than mutants, corroborating our taste preference study. In contrast, PTC lacks hydrogen bonds in the binding pocket but exhibits pi–pi stacking interactions with the native structure. Structures with mutations at the 49th or 296th position showed the largest root mean square deviations and fluctuations. A triple mutation increases surface area and volume, making the 262nd position critical to the binding pocket. These results highlight the functional roles of these three residues in hTAS2R38.
The Purinergic Ligand‐Gated Ion Channel 7 Receptor Promotes the Proliferation, Invasion, and Migration of Breast Cancer Cells
Authors: Wang Xin , Peng Xiaoxiang , Cao Yahui , Zhu Xiaodi , Du Yanan , Yu Qingqing , Zhao Ronglan 
Published: February 2025

ABSTRACTPurinergic ligand‐gated ion channel 7 receptor (P2X7R) has essential functions in tumor proliferation, apoptosis, metastasis, and invasion, and the purpose of this study was to explore the effects of P2X7R on the biological behaviors of MCF‐7 and MDA‐MB‐231 cells. A bioinformatics analysis of P2X7R expression in breast cancer was performed and its relationships with overall survival and immune cell infiltration were determined. P2X7R ion channel function was detected via a Fluo‐4‐AM assay. Proliferation, migration and invasion were investigated using CCK‐8, scratch wound healing, and Transwell assays, respectively. The levels of P2X7R, JNK, p‐JNK, Akt, p‐Akt, E‐cadherin, N‐cadherin, vimentin and GAPDH were detected by western blotting. The role of P2X7R on the biological behaviors of MCF‐7 cells was detected in vivo. Bioinformatics analysis revealed an obvious increase in the expression of P2X7R in breast cancer and differences were observed among the different subtypes. High expression of P2X7R was negatively correlated with overall survival and affected immune cell infiltration. The experimental results revealed that both types of cells express functional P2X7R. ATP and BzATP can promote proliferation, invasion, and metastasis after P2X7R activation; upregulate p‐Akt, p‐JNK, N‐cadherin and vimentin; and downregulate E‐cadherin compared with the control group, and the addition of the antagonist A438079 or oxATP or the knockdown of P2X7R could weaken these effects. The activation of P2X7R in breast cancer cells can promote their biological behaviors, indicating that P2X7R is a latent therapeutic target in breast cancer.
Ecological Factors That Predict School Counselors’ Comprehensive School Counseling Program Implementation
Authors: Hilts Derron , Park Eunji , Liu Yanhong 
Published: February 2025

ABSTRACTSchool counselors are tasked with designing and implementing a comprehensive school counseling program (CSCP) to support student development. Although factors influencing CSCP implementation have been studied, a comprehensive model is needed to classify these variables by ecological type, clarifying their unique contributions and varying importance to school counselors’ CSCP implementation. We investigated whether sociocultural factors (e.g., sexual orientation, socioeconomic status), professional development experiences (e.g., ASCA national model training), intrapersonal and interpersonal factors (e.g., self‐advocacy, role stress), and systemic factors (e.g., organizational support, school counselor caseload) uniquely contribute to school counselors’ CSCP implementation. Our sample included 265 school counselors, nationwide. The final hierarchical regression model explained 51% of the variance in CSCP implementation. We also identified several ecological factors with unique contributions in explaining the variance in CSCP implementation. We discussed implications for counseling practice, research, and advocacy.
Structures and Solvation Energies Effects Versus Temperature. An MP2 Investigations in the Framework of Cluster Model
Authors: Hattab Awatef , Malloum Alhadji , Dhaouadi Zoubeida , Russo Nino 
Published: February 2025

ABSTRACTStructures, relative stabilities, solvation enthalpies, and free energies of the cluster in gas and in water phases were investigated in this work using Moller‐Plesset perturbation theory (MP2) and considering a temperature range of 40–400 K. The 12 H2O molecules are distributed between the first, second, and third solvation shells. The calculated distances distances in gas phase are in good agreement with the experimental range which confirms the strong influence of long‐distance interactions in cluster stabilization. Structural comparison between gas and water phases shows that the addition of the bulk solvent causes changes in the cation‐water bond lengths of few hundredths of angstroms. The obtained solvation free energy of beryllium ion in water at room temperature (298.15 K) results in b − 575.1 kcal mol−1 in very good agreement with the corresponding experimental counterpart. The computed solvation free energies increase as a polynomial function of the temperature while the change in the solvation enthalpies is found to be negligible.
Rethinking Psychotherapy Training and Supervision: The Case for Deliberate Practice
Authors: Vaz Alexandre , McLeod Julia , Nissen‐Lie Helene A. 
Published: February 2025

ABSTRACTPsychotherapy supervision research has led to mixed, often disappointing results as to its effects on clinicians' skills acquisition and final treatment outcomes. Put simply, it is unclear if traditional supervision methods reliably increase therapist effectiveness. To answer this longstanding challenge, Deliberate Practice (DP) is now increasingly being recognized by leading authors and researchers as an effective method for enhancing therapists' skills. Despite this growing agreement about the potential advantages of DP methods, there remains a shortage of research, guidelines and real‐world case presentations for their implementation in clinical supervision. In this introductory paper, we present an issue of the Journal of Clinical Psychology: In Session that showcases diverse modalities and approaches through which DP can be integrated into clinical supervision. To set the stage, this paper presents the major definitions, research evidence, and potential benefits and challenges of a DP‐informed psychotherapy supervision. We highlight that while available research is promising, much is still needed to elevate the promise of DP into an evidence‐based learning method that reliable increases therapist's skills and outcomes. As such, we conclude with a call encouraging clinicians, trainers and researchers alike to experiment with the methods here described and contribute to this exciting new development in the field.
The Effects of the Early and Late Phases of Septic Shock on the Population Pharmacokinetics of Vancomycin
Authors: Lexnoi Tanisa , Boonpeng Apinya , Santimaleeworagun Wichai , Chaisiri Kessarin , Dechsanga Jutamas , Vattanavanit Veerapong , Ungthammakhun Chutchawan , Sitaruno Sirima 
Published: February 2025

AbstractPathophysiologic changes in the early and late phases of septic shock affect the pharmacokinetic (PK) parameters, varying dose adjustments may be necessary. This study aimed to create the PK models of vancomycin in the early and late phases of septic shock and to describe the association between the area under the curve from 0 to 24 h (AUC0‐24) and acute kidney injury (AKI). The data from patients with septic shock receiving vancomycin was collected either prospectively or retrospectively. A nonlinear mixed‐effects modeling approach was used to develop the PK models. A total of 208 septic shock patients were enrolled and classified into the early (n = 96) and the late phase (n = 112). A two‐compartment PK model is the best base model for both phases of septic shock. The model that best predicted the clearance (CL) of both phases was the 2021 Chronic Kidney Disease Epidemiology Collaboration (CKD‐EPI) creatinine equation, which was not indexed to body surface area (BSA). Albumin (ALB) was a covariate associated with vancomycin CL only in the late phase. The typical values of CL and volume of distribution (Vd) in the early phase were 1.71 L/h and 68.94 L. In the late phase, CL was 1.65 L/h, and Vd was 66.36 L. The AKI was observed in patients with a high simulated AUC0‐24. The population PK model of vancomycin in the early and late phases of septic shock has been established. The CKD‐EPI not indexed to BSA predicts vancomycin CL in both phases. ALB was associated with CL in the late phase.
Reproducibility of a new device for robotic‐assisted TKA surgery
Authors: Alesi Domenico , Rinaldi Vito Gaetano , Cerasoli Tosca , Valente Davide , Marcheggiani Muccioli Giulio Maria , Zaffagnini Stefano 
Published: February 2025

AbstractPurposeEnhancing implant placement to achieve optimal gap balance is crucial in total knee arthroplasty (TKA). Given the limited precision of traditional instrumentation, tools like computer‐assisted surgery and robotic‐assisted TKA have emerged. This experimental cadaveric study aimed to evaluate the accuracy and reproducibility of the collaborative image‐free Robin robotic system to support its future clinical application.MethodsFifteen cadaveric specimens were treated by eight experienced TKA surgeons. All surgeons, experts in computer‐assisted TKA but new to the Robin system, received standardized training. The Robin system uses a robotic arm to position and hold a universal cutting jig, while surgeons perform osteotomies. The indicator for registration repeatability was the alignment of the cutting block position with the previous pin placement. Bony resection, angles and axes were evaluated by comparing the preoperative planning values to the ones obtained with the Robin system with a validated navigation system.ResultsThere were no statistically significant differences between the planned and measured values for most resection angles, except for femoral and tibial orientation on sagittal plane (0.6 ± 0.8° and 0.6 ± 1.0°, respectively). Similarly, no statistically significant differences were recorded for resection thickness values, except for the distal medial femoral cut (0.8 ± 0.7 mm). Moreover, these results showed consistency among the different first‐time users.ConclusionsThe study found that the Robin robotic system closely matched the preoperative plan for TKA, demonstrating high accuracy and consistency among first‐time users. This allows surgeons to easily achieve their planned targets without having to adapt their surgical technique, potentially improving both efficiency and outcomes even when handling complex cases.Level of EvidenceNot applicable.