bluuebunny/crossref_metadata_2025_split huggingface dataset:
Glucocorticoid Discontinuation in Patients With Systemic Lupus Erythematosus With Prior Severe Organ Involvement: a Single-center Retrospective Analysis
Authors: Okada Masato , Fukui Sho , Ikeda Yukihiko , Suda Masei , Tamaki Hiromichi , Nakai Takehiro 
Published: September 2021

Abstract
Background:Long-term glucocorticoid use in systemic lupus erythematosus (SLE) may have significant side effects; however, glucocorticoid discontinuation is occasionally associated with disease flare-ups. Therefore, we evaluated the risk factors for disease flares and the flare rate upon glucocorticoid tapering in patients with prior severe organ involvement.Methods:Patients with SLE with glucocorticoid tapering at our institution were retrospectively analyzed. We divided the patients according to the presence of prior severe organ involvement and compared flare rates and time to first flare after glucocorticoid discontinuation. Furthermore, we determined risk and protective factors for flares after glucocorticoid discontinuation.Results:A total of 309 patients with SLE were screened; 298 had prednisolone tapered to less than 7.5 mg/day and 75 had glucocorticoid discontinuation. Overall, 73 patients met the inclusion criteria; 49 were classified as SLE with prior severe organ involvement. No statistical differences were noted in the 52-week flare rate and time to first flare after glucocorticoid discontinuation between patients with and without prior severe organ involvement (52-week flare rate: 16.7% vs. 18.2%, p = 1.0; time to first flare: 322 [280, 1169] vs. 385 [304, 2345] days, p = 0.33). Hypocomplementemia, elevated anti-dsDNA antibody titers of more than twice the upper limit of the laboratory reference range, and positive anti-Smith/anti-ribonucleoprotein antibody were negatively associated with flare-free remission.Conclusion:Glucocorticoid discontinuation can often be achieved in patients with SLE without increasing flare risk in most patients with prior severe organ involvement, especially when the disease is clinically and serologically stable.
Spatial Phase Synchronisation of Pistachio Alternate Bearing
Authors: Sakai Kenshi , Brown Patrick , Rosenstock Todd , Upadhyaya Shrinivasa , Hastings Alan 
Published: September 2021

Abstract
Nonlinear physics and agroecosystems can be of great relevance in the synchronisations of chaotic oscillators. The endogenous dynamics of the seed production of perennial plant species which include alternate bearing and masting, portray typical synchronisation patterns in nature and can be modelled using a tent map known as a resource budget model (RBM). This study investigates the collective rhythm in 9,562 pistachio trees caused by their endogenous network dynamics and exogenous forces (common noise). Common noise and a local coupling of RBMs are the two primary factors emerging from the bearing phase synchronisation in this orchard. The in-phase/out-of-phase analysis technique quantifying the strength of the phase synchronisation in trees (population /individual) allows us to study the observed spatial synchrony in detail. We demonstrate how three essential factors, i.e. (a) common noise, (b) local direct coupling, and (c) the gradient of the cropping coefficient, explain the spatial synchrony of the orchard. Here, we also show that the methodology employing nonlinear physics to study agroecological systems can be useful for resolving practical problems in agriculture including yield variability and spatial synchrony which often compromise efficient resource management.
Using CFD To Assess The Impact of Helical Baffle On The First- Law And Second-Law Performance of Water-CuO Nanofluid Inside A Hairpin Heat Exchanger
Authors: Shahsavar Amin , Toghraie Davood , Barnoon Pouya 
Published: September 2021

Abstract
This study is devoted to the numerical assessment of the influence of helical baffle on the hydrothermal aspects and irreversibility behavior of the turbulent forced convection flow of water-CuO nanofluid (NF) inside a hairpin heat exchanger. The variations of the first-law and second-law performance metrics are investigated in terms of Reynolds number (Re), volume concentration of NF (φ) and baffle pitch (B). The results showed that the NF Nusselt number grows the rise of both the Re and φ whereas it declines by boosting with the rise of baffle pitch. In addition, the outcomes depicted that the rise of both the T and φ results in the rise of pressure drop, while it declines with the increase of baffle pitch. Moreover, it was found that the best first-law performance of the NF belongs to the case B=33.3 mm, φ=2% and Renf=10000. Furthermore, it was shown that irreversibilities due to fluid friction and heat transfer augment with the rise of Re while the rise of baffle pitch results in the decrease of frictional irreversibilities. Finally, the outcomes revealed that with the rise of baffle pitch, the heat transfer irreversibilities first intensifies and then diminishes.
Examining Stakeholder’s Views On Refugee Healthcare Needs, Current Barriers in Accessing Healthcare Services and Future Healthcare Direction in New Zealand: A Qualitative Phenomenological Approach
Authors: Sherif Bafreen , Awaisu Ahmed , Kheir Nadir 
Published: September 2021

Abstract
Background

The annual New Zealand refugee quota was increased to 1500 places from 2020 onwards as a response to the global refugee crisis. The specific healthcare needs of refugees are not clearly understood globally and communication between healthcare providers and refugees remains poor.
Methods

A phenomenological qualitative methodology was employed to conduct semi-structured interviews among purposively selected stakeholders who work in refugee organisations and relevant bodies in New Zealand.
Results

The participants indicated the need for a national framework of inclusion, mandating cultural competency training for frontline healthcare and non-healthcare personnel, creation of a national interpretation phone line, and establishing health navigators. Barriers to accessing health services identified included some social determinants of health such as housing and community environment; health-seeking behaviour and health literacy; and social support networks. Future healthcare delivery should focus on capacity building of existing services, including co-design processes, increased funding for refugee-specific health services, and whole government approach.
Conclusion

Policymakers and refugee organisations and their frontline personnel should seek to address the deficiencies identified in order to provide equitable, timely and cost-effective healthcare services for refugees in New Zealand.
A revised analysis of ferrihydrite at liquid helium temperature using Mössbauer spectroscopy
Authors: Byrne James M. , Kappler Andreas 
Published: September 2021

Abstract
Short-range-ordered Fe(III) minerals such as ferrihydrite (Fh) are ubiquitous in the environment, are key players in biogeochemical cycling, and sorb trace elements and nutrients. As such, it is important to be able to identify the presence of such minerals in natural samples. Fh is commonly observed to be X-ray amorphous and cannot be easily analyzed using X-ray diffraction, meaning that spectroscopic methods such as X-ray absorption or 57Fe Mössbauer spectroscopy (MBS) are necessary for accurate identification and quantification. Despite decades of research into Fh using MBS, there is a discrepancy in the literature about the exact parameters applicable to the mineral when measured at liquid helium temperature. Fh is frequently fitted with either one, two, or three hyperfine sextets with little interpretation applied to the meaning of each, which is problematic as a one sextet model does not account for the asymmetric lineshape frequently observed for Fh. Here, we address inconsistencies in the fitting of Fh and provide a more standardized approach to its identification by MBS. We present a systematic comparison of different fitting methods, notably based on Lorentzian and Voigt functions. We suggest that the most suitable approach to fitting pure Fh at liquid helium temperature is with two sextets (A and B) fitted using an extended Voigt-based function with the ability to apply probability distributions to each hyperfine parameter. 2-line Fh: A (δ = 0.49 mm/s; ε = 0.00 mm/s; Bhf = 50.1 T) and B (δ = 0.42 mm/s; ε = –0.01 mm/s; Bhf = 46.8 T) 6-line Fh: A (δ = 0.50 mm/s; ε = –0.03 mm/s; Bhf = 50.2 T) and B (δ = 0.40 mm/s; ε = –0.05 mm/s; Bhf = 47.1 T). We interpret the two sextets to be due to either differences in the coordination environment of iron, i.e., in tetrahedral or octahedral sites, the presence of a disordered surface phase, or a combination of both. We hope that provoking a discussion on the use of MBS for Fh will help develop a greater understanding of this mineral, and other short-range ordered iron minerals, which are so important in environmental processes.
Computational Analysis Illustrates the Mechanism of Qingfei Paidu Decoction in Blocking the Transition of COVID-19 Patients from Mild to Severe Stage
Authors: Chen Wei , Li Xianhai , Xiang Liu , Lin Yue , Tang Qiang , Meng Fanbo 
Published: September 2021

Background:The epidemic of SARS-CoV-2 has made COVID-19 a serious threat to human health around the world. The severe infections of SARS-CoV-2 are usually accompanied by higher mortality. Although the Qingfei Paidu Decoction (QFPDD) has been proved to be effective in blocking the transition of COVID-19 patients from mild to severe stage, its mechanism remains unclear.Objective:This study aims to explore the mechanism of QFPDD in blocking the transition of COVID- 19 patients from mild to severe stage.Materials and Methods:In the process of screening active ingredients, oral bioavailability (OB) and drug likeness (DL) are key indicators, which can help to screen out pivotal compounds. Therefore, with the criteria of OB≥30% and DL≥0.18, we searched active ingredients of QFPDD in the Traditional Chinese Medicine Systems Pharmacology (TCMSP, https://tcmspw.com/) by using its 21 herbs as keywords.Results:We filtered out 6 pivotal ingredients from QFPDD by using the bioinformatics method, namely quercetin, luteolin, berberine, hederagenin, shionone and kaempferol, which can inhibit the highly expressed genes (i.e. CXCR4, ICAM1, CXCL8, CXCL10, IL6, IL2, CCL2, IL1B, IL4, IFNG) in severe COVID-19 patients. By performing KEGG enrichment analysis, we found seven pathways, namely TNF signaling pathway, IL-17 signaling pathway, Toll-like receptor signaling pathway, NFkappa B signaling pathway, HIF-1 signaling pathway, JAK-STAT signaling pathway, and Th17 cell differentiation, by which QFPDD could block the transition of COVID-19 patients from mild to severe stage.Conclusion:QFPDD can prevent the deterioration of COVID-19 in the following mechanisms, i.e. inhibiting SARS-CoV-2 invasion and replication, anti-inflammatory and immune regulation, and repairing body damage. These results will be helpful for the prevention and treatment of COVID-19.
CHARACTER EDUCATION IN THE ACEHNESE IDIOMS OF KUALA BATEE COMMUNITY OF SOUTHWEST ACEH
Authors: Sanusi Sanusi 
Published: September 2021

This study is entitled "Character Education in the Acehnese Idiom in the Kuala Batee Community of Southwest Aceh”. The Acehnese idiom was used as a support in advising and as a means of maintaining existing norms in the society. A Society is one of the most influential molders of character education because of its interactions. The values of traditional culture are recognized by all levels of the society in the regions and nationalities that become national identities. Not only culture, local languages also need to be used in daily interactions in society so that they do not experience a serious decline, which will eventually disappear over the time. In this case, the Acehnese Idiom became a medium to spread the value of character education to the next generation. The purpose of this study is to describe the Acehnese expressions that contain the values of character education in the community of Kuala Batee Southwest Aceh. The method of this research is a descriptive qualitative. Interview was used as an instrument. In this study, 8 subjects are chosen using purposive sampling that consist of tuhapheut and village elders in the community. The location of this study is in Kuala Batee District, Southwest Aceh. There are 18 character values in the Acehnese Idiom in the community of Kuala Batee, Southwest Aceh which consists of; religious, honest, tolerance, discipline, hard work, creative, independent, democratic, curiosity, national spirit, love of the homeland, respect for achievement, friendly/communicative, love peace, love to read, care for the environment, social care and responsibility. The expressions found in the Kuala Batee community are in the form of one line, two lines, three lines and four lines. The Acehnese idiom in the community of Kuala Batee Southwest Aceh is in the oral form which has its own meaning and use as an advice relating to divinity, self, others and the environment. Based on the above conclusions, the author suggests the community to preserve the Acehnese idiom so that it becomes a legacy for the next generation. To the government, it is hoped that they will support to publish references related to Acehnese idioms and other types of folklore related to Acehnese culture so that they can add references to other studies.
LAFAL LAYTA DALAM AL-QUR’AN
Authors: Bakar Syukran Abu , Maysarah Syarifah 
Published: September 2021

This article is a research about the word of layta in the Qur’an. Generally, the using of the word of layta in the Qur'an referred to unbelievers when expressing their remorse in the afterlife. However, there are Qur'an verses that use the word of layta referred to the believers and in the context of the world. Due to the variations of this designation, the author feels the need for more in-depth research related to the using of the word of layta in the Qur'an. This research is library research, using content analysis techniques in processing data. The data sources that the authors refer to are Balâghah books such as al-Balâghat al-Wâdhihah, and the book of interpretation. The results of this study can be concluded that the word of layta is mentioned fourteen times in the Qur'an, with three speakers: believers, unbelievers and hypocrites. The meanings that indicated by this word are regret, delusion and good wishes. Then, these meanings are connected with psychology. And the result is that if the pronunciation of this word relies on the believer, it shows a positive meaning, such as a sense of empathy. Conversely, if it relies on other than believers, it has a negative meaning.Abstrak: Tulisan ini merupakan penelitian terhadap lafal layta yang terdapat dalam al-Qur’an. Umumnya, penggunaan lafal layta dalam al-Qur’an disandarkan kepada orang-orang kafir ketika mereka mengungkapkan penyesalannya di akhirat. Namun, ada ayat al-Qur’an yang menggunakan lafal layta dengan disandarkan kepada orang mukmin dan dalam konteks dunia. Berangkat dari adanya variasi penyandaran lafal tersebut, penulis merasa perlu meneliti lebih dalam terkait penggunaan lafal layta di dalam al-Qur’an. Penelitian ini bersifat kepustakaan (library research), dengan menggunakan teknik analisa isi (content analysis) dalam mengolah data. Sumber data yang penulis rujuk adalah kitab-kitab Balâghah seperti al-Balâghat al-Wâdhihah dan kitab-kitab tafsir. Hasil dari penelitian ini dapat disimpulkan bahwa lafal layta disebut sebanyak empat belas kali dalam al-Qur’an, yang disandarkan kepada tiga subjek, yaitu mukmin, kafir dan munafik. Makna yang ditunjukkan lafal layta adalah penyesalan, angan-angan dan harapan yang baik. Selanjutnya, makna-makna tersebut dihubungkan dengan ilmu psikologi. Maka, hasil yang didapatkan adalah jika pengucapan lafal ini disandarkan kepada orang mukmin, ia menunjukkan makna positif, seperti rasa empati. Sebaliknya, jika disandarkan kepada selain mukmin, maka ia bermakna negatif.
Analysis of Air Side Needs at Mutiara SIS AL-JUFRI Airport Palu
Authors: Labaso E.R. , Tahir A. , Susilo M. 
Published: September 2021

The city of Palu is the capital of the province of central Sulawesi which has hajj waiting list 0f around 31,384 pilgrims with a qouta of 1986 pilgrims until 2034. Garuda indonesia has prepared four tipes of air craft that will serve these filghts including Boeing B777-300ER, B747-400, A330-300 and A330-200. In this study use the secondary data for the next 10 and 20 years forcasting uses the econometric method. The data needed includes climatology, passenger and air craft characteristic at Mutiara Al Jufri Airport. The standard refers to the ICAO. Based on the calculation result obtained that in the exixting condition, the length and width of the runway is 2,510 x 45 m and the width of taxiway is 23 m and the dimension of the apron are 373 x 311,2 m. In 2027, the length of the runway will be 3786 m with a width of 45m, and the width of taxiway 23 m. Apron dimension 541,5 x 195,5 m2. In 2037, the dimension of the runway and taxiway are still fixed, but the apron dimension changes to 714 x 195,5 m.
Keywords: Mutiara Sis Al-Jufri Palu Airport, Runway, Taxiway, Apron
The Image of the Orthodox Clergy in Russian Genre Painting of the 19th and Early 20th Century
Authors: Sankova Svetlana M. 
Published: September 2021

The article traces the transformation of the artistic public's view on the clergy and their place in the life of Russia on the basis of the images of priests created by domestic masters of the genre in the 19th – early 20th centuries. Genre painting originated in Russia in the second quarter of the 19th century and allowed artists to move away from symbolic academic themes and turn to subjects from the everyday life of their contemporaries. However, as a rule, there was no place for the clergy in those works. The exception was the work of A.G. Venetsianov, who was at the root of the creation of genre painting in Russia. In the period of liberal reforms, the church was viewed as something reactionary and clergy was often portrayed in sharply satirical or comic situations (V.G. Perov, F.S. Zhuravlev). In the post-reform period and with the development of realistic worldview, the images of the priest lost their comic focus on the canvases of K.A. Savitsky, G.G. Myasoedov and I.E. Repin. Late 19th and early 20th centuries for the Russian culture was the period of searching spirituality and coming to understand approaching social upheavals in Russian culture, which was clearly demonstrated by M.V. Nesterov's turn to depicting the image of a priest. His disciple P.D. Korin, who witnessed active persecution of the church in the early 1920s, emphasized in his famous, but unfinished portraits of priests the heroic resistance of the clergy to impending persecution. It is important to say that after decades the artist did not get back to the unfinished canvas, since the situation in the country changed, and the genre of the painting changed to historical.
Blockwise Analysis of Health Indicators of Gadchiroli District using Composite Index: An application of GKG Algorithm
Authors: Gotmare Anil D , Khot P.G. , Gotmare Shraddha R. 
Published: September 2021

Gadchiroli district is a part of Vidarbha, Traibal district away from 200 KM from sub capital of Maharashtra, Nagpur, Gadchiroli is well known tribal district of vidarbha. Total forest cover of the district is around 78% of total geographic area. District has 12 blocks with 6 revenue division. It is a notified tribal district having 8.61%–81.50% tribal population in different blocks and block-wise urbanization varies from 0.00% to 37.10%. Objective: Objective of present research paper is to device tool to rank the blocks of the district according to community health status exist in blocks and accordingly assess community health status at block level in Gadchiroli district.
Variabilitas, Heritabilitas, dan Hasil Padi Gogo F3 Persilangan Kultivar Lokal Aceh x Ciherang
Authors: Yenni Marnita  , Ainul Mardiyah  , Muhammad Syahril  
Published: September 2021

Peningkatan luas lahan terdampak kekeringan akibat perubahan iklim menuntut pemulia untuk merakit varietas padi yang adaptif pada kekeringan. Tujuan penelitian ini untuk mendapatkan informasi heritabilitas populasi famili F3 hasil persilangan kultivar Sileso (tetua berdaya hasil tinggi toleran kering) dengan varietas Ciherang (tetua berumur genjah) dan untuk mendapatkan genotipe yang berdaya hasil tinggi berumur genjah. Metode penelitian yang dilakukan adalah menanam populasi F3, resiprokalnya, dan tetua. Penelitian dilaksanakan di kebun percobaan Fakultas Pertanian Universitas Samudra, Langsa, Aceh, mulai Agustus sampai Desember 2020. Nilai heritabilitas tinggi pada karakter hasil pertanaman dan umur panen hanya diperoleh pada famili A1B dan A2B. Populasi A1B memiliki nilai heritabilitas hasil per tanaman sebesar 0.61 dan umur panen sebesar 0.85. Populasi A2B memiliki nilai heritabilitas hasil per tanaman sebesar 0.68 dan umur panen sebesar 0.63. Hasil seleksi diperoleh 11 genotipe dengan hasil tinggi berumur genjah yaitu: A3B(13), A1B(25), A1B(201), A1B(208), A1B(282), A1B(297), A1B(303), A2B(38), A2B(221), A2B(358), dan A2B(424) dengan rata-rata hasil per tanaman 90.67 g dan umur panen 117 hari setelah tanam.
Kata kunci: resiprokal, toleran kering, umur genjah
Pertumbuhan dan Hasil Buncis Tegak di Bawah Naungan di Dataran Rendah
Authors: Dian Diani Tanjung  , Heni Purnamawati  , Anas Dinurrohman Susila  
Published: September 2021

Buncis tegak (Phaseolus vulgaris L.) berpotensi ditanam di dataran rendah dan menjadi tanaman sela, akan tetapi terkendala suhu tinggi dan intensitas cahaya rendah di bawah naungan yang mempengaruhi pertumbuhan tanaman. Tujuan penelitian adalah memperoleh informasi pertumbuhan dan hasil buncis tegak terkait adaptasinya terhadap naungan. Penelitian dilaksanakan di Kebun Percobaan Pusat Kajian Hortikultura Tropika (PKHT) IPB, ketinggian tempat 250 m dpl, dari bulan Oktober 2019 hingga Januari 2020. Percobaan menggunakan rancangan petak tersarang dua faktor dengan empat ulangan. Faktor pertama tiga taraf naungan, yaitu 0, 25, dan 50%. Faktor kedua buncis tegak varietas Balitsa 2, Balitsa 3, dan buncis rambat Lebat 3 sebagai pembanding. Hasil menunjukkan ketiga varietas buncis baik tipe pertumbuhan tegak maupun rambat dapat ditanam di bawah naungan dengan naungan terbaik 25%. Tanaman buncis di bawah naungan 25% mampu mempertahankan jumlah daun, jumlah cabang, mempercepat umur berbunga, dan mempertahankan komponen hasil tetap optimal. Naungan pada buncis tegak meningkatkan tinggi tanaman dan diameter batang sehingga resiko rebah menurun. Varietas buncis tegak terbaik yang dapat tumbuh di dataran rendah adalah Balitsa 3 karena tanaman lebih tinggi, diameter batang besar, jumlah daun dan cabang lebih banyak, berbunga lebih cepat, serta komponen hasil besar.
Kata kunci: adaptasi, Balitsa, buncis tipe tegak, intensitas cahaya