bluuebunny/crossref_metadata_2025_split huggingface dataset:
Behaviour change and physical activity interventions for physical activity engagement in community dwelling adults with chronic obstructive pulmonary disease: protocol for a systematic review
Authors: Hanrahan Ciara , Broderick Julie , O’Connor Terence M. , McVeigh Joseph G. 
Published: October 2021

Background: Chronic obstructive pulmonary disease (COPD) is a complex respiratory disease and the third leading cause of death worldwide. Pulmonary rehabilitation is recognised as the gold standard of care in the management of COPD, however engagement with pulmonary rehabilitation is low and maintenance of a physically active lifestyle in community dwelling adults with COPD is poor. Supporting positive behaviour change in people with COPD could help to increase their engagement with physical activity. This systematic review will examine behaviour change and physical activity interventions delivered to community dwelling adults with COPD with the aim of increasing physical activity engagement. Interventions will be mapped against Michie’s theoretical domains framework (TDF) to inform clinical practice and health policy. Methods: The following databases will be searched from inception until December 2021: Web of Science, CENTRAL, MEDLINE (via EBSCO), EMBASE, APA PsychINFO, CINAHL (via EBSCO), AMED, PROSPERO, Cochrane Airways Trials Register. Reference lists of the relevant studies and grey literature will be searched using Grey Literature Report, Open Grey and Google Scholar search engines. Relevant studies will be systematically reviewed and subject to quality appraisal to determine the impact of behaviour change and physical activity interventions on outcomes of community-dwelling adults with COPD. Interventions will be mapped to Michie’s TDF and a narrative synthesis with respect to nature, effectiveness on target population and setting/environment will be provided. Findings will be reported in relation to the generalisability of the primary results and research question, and will include secondary findings on quality of life, self-reported participation in physical activity, exercise capacity, adverse events and intervention adherence. The review will be presented according to the PRISMA guidelines 2020. Conclusions: This systematic review is necessary to explain the impact of behaviour change and physical activity interventions on outcomes of community dwelling people with COPD. PROSPERO registration: CRD42021264965 (29.06.2021)
Promoting effect of acylated homoserine lactone on the healing of tissue damage in model rats with incontinence-associated dermatitis
Authors: Mugita Yuko , Minematsu Takeo , Nakagami Gojiro , Sanada Hiromi 
Published: October 2021

Objective:One of the most common complications in patients with incontinence is incontinence-associated dermatitis (IAD). This study was conducted to determine the pathophysiology of the healing process of IAD and to develop an effective therapeutic approach according to its pathophysiology.Method:IAD was reproduced on a dorsal rat skin by applying agarose gel containing water and enzymes, and inoculating it with bacteria. Examination of the IAD healing process suggested that the promotion of keratinocyte migration and improvement of basement membrane enhance keratinocyte layer elongations, which contribute to IAD healing. A therapeutic approach using N-(3-oxotetradecanoyl)-L-homoserine lactone, which is one of the acylated homoserine lactones (AHLs) and can promote keratinocyte migration in vitro, was applied on the IAD area in rats.Results:AHL treatment after IAD development resulted in an earlier tipping point for recovery than the vehicle treatment. Histological and immunohistological analyses revealed that the tissue surface was already covered by the epidermis, indicating the results of elongation of the keratinocyte layer from hair follicles. The characteristics of the alignment of basal keratinocytes, the existence of stratum corneum, and the membrane-like distribution of the components of basement membrane were similar to those of a normal epidermis.Conclusion:These results suggested that AHL application possibly contributed to earlier IAD healing before progressing to a severe state. Although elongation of the keratinocyte layer was observed in both the AHL and vehicle groups, the possibility that AHL application promotes IAD healing was suggested. The new concept of the enhancement of keratinocyte migration as a therapeutic approach for IAD would change the skin care strategy for IAD in the healthcare setting.
Ultrafast single-photon detection at high repetition rates based on optical Kerr gates under focusing: erratum
Authors: Fattah Abdul-Hamid , Flatae Assegid Mengistu , Farrag Amr , Agio Mario 
Published: October 2021

Two typos are corrected, and the linear refractive index

n

is removed from the expressions of
the phase shift in Opt. Lett. 46, 560
(2021)OPLEDP0146-959210.1364/OL.414895. The removal of

n

reduces the gate efficiency, but it
does not affect the general findings. Here, we present the corrected
equations and the corresponding new numerical results, showing that
increasing the pulse energy from 1.8 nJ to 4 nJ leads to nearly the
same results of Opt. Lett. 46, 560
(2021)OPLEDP0146-959210.1364/OL.414895.
High accuracy measurement of the ground-state hyperfine splitting in a 113Cd+ microwave clock: erratum
Authors: Miao K. , Zhang J. W. , Sun X. L. , Wang S. G. , Zhang A. M. , Liang K. , Wang L. J. 
Published: October 2021

We present an erratum to our Letter [Opt. Lett.
40, 4249 (2015)OPLEDP0146-959210.1364/OL.40.004249].
This erratum corrects the nuclear Lande factor
gI in Eq. (2). After correcting the error,
the final ground-state hyperfine splitting frequency of the

113

C

d

+

ion is determined to be
15199862855.0287(10) Hz.
Interleukin-22 mitigates acute respiratory distress syndrome (ARDS)
Authors: Taghavi Sharven , Jackson-Weaver Olan , Abdullah Sarah , Wanek Alanna , Drury Robert , Packer Jacob , Cotton-Betteridge Aaron , Duchesne Juan , Pociask Derek , Kolls Jay 
Published: October 2021

Background
The goal of this study was to determine if IL-22:Fc would Acute Respiratory Distress Syndrome (ARDS).

Summary background data
No therapies exist for ARDS and treatment is purely supportive. Interleukin-22 (IL-22) plays an integral component in recovery of the lung from infection. IL-22:Fc is a recombinant protein with a human FC immunoglobulin that increases the half-life of IL-22.

Study design
ARDS was induced in C57BL/6 mice with intra-tracheal lipopolysaccharide (LPS) at a dose of 33.3 or 100 ug. In the low-dose LPS group (LDG), IL-22:FC was administered via tail vein injection at 30 minutes (n = 9) and compared to sham (n = 9). In the high-dose LPS group (HDG), IL-22:FC was administered (n = 11) then compared to sham (n = 8). Euthanasia occurred after bronchioalveolar lavage (BAL) on post-injury day 4.

Results
In the LDG, IL-22:FC resulted in decreased protein leak (0.15 vs. 0.25 ug/uL, p = 0.02). BAL protein in animals receiving IL-22:Fc in the HDG was not different. For the HDG, animals receiving IL-22:Fc had lower BAL cell counts (539,636 vs 3,147,556 cells/uL, p = 0.02). For the HDG, IL-6 (110.6 vs. 527.1 pg/mL, p = 0.04), TNF-α (5.87 vs. 25.41 pg/mL, p = 0.04), and G-CSF (95.14 vs. 659.6, p = 0.01) levels were lower in the BAL fluid of IL-22:Fc treated animals compared to sham.

Conclusions
IL-22:Fc decreases lung inflammation and lung capillary leak in ARDS. IL-22:Fc may be a novel therapy for ARDS.
Assessment of serum amylase, lipase and associated factors among patients with visceral leishmaniasis treated with sodium stibogluconate/paromomycin at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia
Authors: Mengstie Tiget Ayelgn , Endale Hiwot Tezera , Mulaw Tadele , Abdella Aman Mossa , Mohammed Rezika , Malik Tabarak , Dessie Gashaw 
Published: October 2021

Background
Visceral leishmaniasis (VL) is a life-threatening parasitic disease next to malaria, which is responsible for the death of 50,000 patients annually. It has three major clinical stages, including visceral, cutaneous, and mucocutaneous leishmaniasis. Ethiopia is one of the east African countries commonly affected with leishmanisis disease. There are many drugs for leishmaniasis, including sodium stibogluconate and paromomycin combined therapy. However, the adverse effect of those combined drugs is not well-defined. Therefore, the purpose of this study was to assess serum amylase, lipase, and associated factors among patients with VL treatment with those combined drugs.

Methods
Hospital-based cross-sectional study was conducted at the University of Gondar Comprehensive Specialized Hospital Leishmaniasis Research and Treatment Center from February to September 2020 G.C. Simple random sampling technique was utilized to select study participants. The study participants who fulfill the inclusion criteria were included in the study with written informed consent. 5 ml of blood was withdrawn by an experienced health professional to analyze serum amylase and lipase level. Descriptive data was presented by tables, charts and graphs. Data was cleared, entered by Epi-data version 3.1 then transfer to STATA 14.1 SE version and for analysis paired t-test was used, for factors correlation and regression was used. Those factor variable who have p-value <0.25 was filtered and goes to multivariate regression and p-value <0.05 was considered as significant variables.

Results
The result of this study showed that there was a significant mean difference between serum pancreatic amylase and lipase before and after treatment. The mean ± SD level of serum amylase after treatment showed a statistically significant elevation (P<0.001) as compared to its level before treatment. Similarly, the mean ± SD level of serum lipase after treatment showed a statistically significant elevation (P<0.001) as compared to its level before treatment. There was also significant association between age and baseline serum amylase as compared to serum amylase after treatment. Similarly, there was also significant relation of age and serum lipase with serum lipase after treatment.

Conclusion
In this study, the level of serum amylase and lipase at treatment of cure was higher and there was an increase in mean serum amylase and lipase after a patient taking sodium stibogluconate and paromomycin combined drugs. Consequently, the elevated result of these biochemical profiles mainly associated with drug induced adverse effect and associated risk factors in VL patients.
Diabetic macular edema: Safe and effective treatment with intravitreal triamcinolone acetonide (Taioftal)
Authors: Sorrentino Francesco Saverio , Bonifazzi Claudio , Parmeggiani Francesco 
Published: October 2021

Purpose
To suggest the safety and efficacy of preservative-free triamcinolone acetonide intravitreal injectable suspension (Taioftal) for the treatment of diabetic macular edema.

Methods
A prospective clinical study involved 49 patients (49 eyes), that were treated with Taioftal and followed-up for six months. Complete ophthalmic examination, including spectral domain optical coherence tomography, was performed at baseline, and at month 1, 3, 6 after the intravitreal injection. Accurate collection and analysis of best-corrected visual acuity (BCVA), central foveal thickness (CFT), intraocular pressure (IOP), and adverse events (AEs) were carried out in order to evaluate visual function and macular morphology before and after treatment

Results
Median BCVA value chosen as comparing statistics was significantly improved at every follow-up time points (gain of 6 letters at month 1, 12 at month 3 –improvement up to 24% at month 3 with stabilization until month 6) compared to baseline, as certified by Kruskal-Wallis rank sum test (P<0.05). Median CFT significantly waned at each follow-up times (decrease of about 65 μm at month 1, 155 at month 3 –reduction up to 28% at month 3 keeping good outcome until month 6) compared to baseline (P<0.05). IOP elevation, with no severe increases, was the most common among spotted AEs (median of 23 mmHg at month 1, 20 at month 3).

Conclusion
Intravitreal injection of preservative-free triamcinolone (Taioftal) is an effective, safe and inexpensive drug used to improve visual acuity and reduce central foveal thickness in eyes affected by diabetic macular edema during an average time of 6 months. Temporary, never severe, elevation of IOP is totally manageable with topical medications. No serious vision-threatening complications are related to the use of intravitreal triamcinolone injections.
Performance enhancement of numerical approaches for scheduling problem on machine single
Authors: Selt Omar 
Published: October 2021

In this paper, we consider a single-machine scheduling problem, with the aim of minimizing the weighted sum of the completion time. This problem is NP-hard, making the search for an optimal solution very difficult. In this frame, two heuristics (H1), (H2) and metaheuristic tabu search are suggested.To improve the performance of this techniques, we used, on one hand, different diversification strategies (TES1 and TES2) with the aim of exploring unvisited regions of the solution space. On the other hand, we suggested three types of neighborhoods (neighborhood by swapping, neighborhood by insertion and neighborhood by blocks).It must be noted that tasks movement can be within one period or between different periods.
Effect of a Neoprene Knee Sleeve on Performance and Muscle Activity in Men and Women During High-Intensity, High-Volume Resistance Training
Authors: Hatfield Disa L. , Stranieri Andrew M. , Vincent Lisa M. , Earp Jacob E. 
Published: October 2021

Abstract
Hatfield, DL, Stranieri, AM, Vincent, LM, and Earp, JE. Effect of a neoprene knee sleeve on performance and muscle activity in men and women during high-intensity, high-volume resistance training. J Strength Cond Res 35(12): 3300–3307, 2021—The purpose of this study was to assess the effects of a commercially available neoprene knee sleeve (KS) on exercise performance and muscle activity during an exhaustive leg press exercise. Twenty resistance-trained individuals, 11 men {21.0 ± 2.2 years; 77.7 ± 8.7 kg; 1 repetition maximum (1RM/body mass [BM]): 0.30 ± 0.04} and 9 women (22.0 ± 3.5 years; 66.1 ± 9.1 kg; 1RM/BM: 0.30 ± 0.04), all subjects (21.5 ± 2.8 years; 72.5 ± 10.5 kg; 1RM/BM: 0.30 ± 0.04), participated in 3 testing sessions. The second and third sessions were performed using a counterbalanced and randomized design in which subjects exercised with (WS) or without (NS) KSs and performed 6 sets of leg press exercise at 80% of 1RM until failure with a 3-minute rest between sets. Number of repetitions, blood lactate (BL), heart rate (HR), rating of perceived exertion (RPE), and peak and average power were recorded after each set. Surface electromyography (EMG) of the right and left vastus lateralis muscles was also recorded to compare muscle activity between conditions. Significance was set at p ≤ 0.05, and values are presented as mean ± SD. No significant differences were observed in the total number of repetitions for all sets (p = 0.3; WS 75.3 ± 33.7, NS 79.8 ± 34.3) and the number of repetitions per set between conditions (p ≤ 0.05) or between men and women. Similarly, no significance differences (p ≤ 0.05) were observed for BL, HR, RPE, or EMG per set between conditions or between men and women. These results suggest that wearing compressive neoprene KSs has no effect on improving performance and associated variables during high-load, high-volume lower-body resistance training.
The Validity, Reliability, and Agreement of Global Positioning System Units—Can We Compare Research and Applied Data?
Authors: Brosnan Ross J. , Watson Greig , Stuart Will , Twentyman Craig , Kitic Cecilia M. , Schmidt Matthew 
Published: October 2021

Abstract
Brosnan, RJ, Watson, G, Stuart, W, Twentyman, C, Kitic, CM, and Schmidt, M. The validity, reliability, and agreement of GPS units—Can we compare research and applied data? J Strength Cond Res 36(12): 3330–3338, 2022—This study's aim was to investigate the validity, within-brand interunit reliability, and between-brand agreement of movement indicators from 3 commonly used global positioning system (GPS) units used in applied and research settings. Forty-two units (GPSports EVO; 10 Hz, n = 13: GPSports HPU; 5 Hz, n = 14: and Catapult S5; 10 Hz, n = 15) were investigated across 3 experiments: a 40-m linear track with all units pushed on a trolley, a sport simulation circuit with all units pulled on a sled, and a similar circuit with 3 models of units placed in a modified GPS vest worn by an athlete between the scapulae. Distance, speed, and acceleration indices were obtained and analyzed with the level of significance set (ρ < 0.05). The results demonstrated good to moderate (% mean difference; 0–6.5%) validity with criterion and good (coefficient of variation [CV] ± 90% confidence interval [CI]: 0–3.9%) interunit reliability for distance and speed in units. Ten hertz units demonstrated good to moderate (CV ± 90% CI: 0.21–5.58%) interunit reliability in all acceleration and deceleration measures, with 5 Hz units having good to poor (CV ± 90% CI: 4.54–12.78%) results. Agreement ranged from good to moderate (% mean difference; 0.01–7.8%) for distance, speed, and absolute acceleration/deceleration. Agreement ranged from good to poor (% mean difference; 2.21–32.74%) in average acceleration. The GPS units investigated can be compared within and between applied and research settings for distance and speed. However, caution is warranted in acceleration indices. This highlights the importance of testing other commonly used GPS models and brands.
METAEVALUACIÓN EN EL PROFESORADO DE EDUCACIÓN FÍSICA
Authors: Chaverra-Fernández B. , Hernández-Álvarez J.L. 
Published: October 2021

Este artículo presenta resultados de una investigación más amplia sobre las concepciones y la acción evaluativa de seis docentes de educación física de Medellín (Colombia). El objetivo específico que se presenta fue: Analizar las reflexiones que pueden surgir en el profesorado una vez finalizado el proceso evaluativo en una unidad didáctica, es decir, la evaluación de la propia evaluación (metaevaluación). El diseño utilizado fue cualitativo, específicamente un estudio de caso múltiple. Se utilizaron como estrategias de recolección de información las entrevistas semi-estructuradas y, cuando fue posible por su existencia, el análisis documental. La investigación permite concluir que, finalizar una unidad didáctica no conlleva necesariamente a una reflexión del profesorado sobre la evaluación realizada. Los pocos cuestionamientos mencionados en sus discursos, se refieren a breves reflexiones sobre los instrumentos o procedimientos realizados, pero no hay una reflexión profunda sobre los propósitos formativos que tiene la evaluación y sobre sus aportes a una enseñanza de calidad.
The Experience of Parents of Hospitalized Children Living With Medical Complexity
Authors: Kemp Kyle A. , Fairie Paul , Steele Brian , McNeil Deborah , Kromm Seija , Johnson David , Santana Maria J. 
Published: October 2021

BACKGROUND AND OBJECTIVESChildren living with medical complexity (CMC) experience frequent hospital admissions. Validated patient-reported experience measures may inform care improvements in this cohort. Our objectives were to examine the comprehensive inpatient experience of CMC by using a validated patient-reported experience measure and compare the results with all other respondents at 2 academic pediatric hospitals in a western Canadian province.METHODSParents completed the Child Hospital Consumer Assessment of Healthcare Providers and Systems survey. Surveys were linked with inpatient records, and an accepted case definition was used to extract records pertaining to CMC. Results were reported as percent in “top box,” represented by the most positive answer choice to each measure. Odds of reporting a top box response were calculated while controlling for demographic and clinical features.RESULTSFrom October 2015 to March 2019, 4197 surveys (1515 CMC; 2682 non-CMC) were collected. Among CMC, the highest-rated measures pertained to being kept informed while in the emergency department, a willingness to recommend the hospital, and parents having a clear understanding of their role in their child’s care. The lowest-rated measures pertained to preventing mistakes and reporting concerns and the quietness of the hospital room at night. Compared with others, parents of CMC reported lower raw results on 20 of the 28 measures. They also reported lower a odds of reporting a top box score on 2 measures and higher odds on 1.CONCLUSIONSParents of CMC revealed many perceived gaps. These findings can be used to inform strategies to improve care among CMC and policies to support the care of CMC and their families.
Factors Associated With Bronchiolitis Guideline Nonadherence at US Children’s Hospitals
Authors: Hester Gabrielle , Nickel Amanda J. , Watson David , Bergmann Kelly R. 
Published: October 2021

BACKGROUND
The objective with this study was to explore factors associated with nonadherence to national bronchiolitis guidelines at 52 children’s hospitals.

METHODS
We included patients 1 month to 2 years old with emergency department (ED) or admission encounters between January 2016 and December 2018 and bronchiolitis diagnoses in the Pediatric Health Information System database. We excluded patients with any intensive care, stay &gt;7 days, encounters in the preceding 30 days, chronic medical conditions, croup, pneumonia, or asthma. Guideline nonadherence was defined as receiving any of 5 tests or treatments: bronchodilators, chest radiographs, systemic steroids, antibiotics, and viral testing. Nonadherence outcomes were modeled by using mixed effects logistic regression with random effects for providers and hospitals. Adjusted odds ratio (aOR) &gt;1 indicates greater likelihood of nonadherence.

RESULTS
A total of 198 028 encounters were included (141 442 ED and 56 586 admission), and nonadherence was 46.1% (ED: 40.2%, admissions: 61.0%). Nonadherence increased with patient age, with both ED and hospital providers being more likely to order tests and treatments for children 12 to 24 months compared with infants 1 ot 2 months (ED: aOR, 3.39; 95% confidence interval [CI], 3.20–3.60; admissions: aOR, 2.97; CI, 2.79–3.17]). Admitted non-Hispanic Black patients were more likely than non-Hispanic white patients to receive guideline nonadherent care (aOR, 1.16; CI, 1.10–1.23), a difference driven by higher use of steroids (aOR, 1.29; CI, 1.17–1.41) and bronchodilators (aOR, 1.39; CI, 1.31–1.48). Hospital effects were prominent for viral testing in ED and admission encounters (intraclass correlation coefficient of 0.35 and 0.32, respectively).

CONCLUSIONS
Multiple factors are associated with national bronchiolitis guideline nonadherence.