bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceptions and Expressions Pertaining to Cultural Ecosystem Services in Urban Green Spaces Using Text Mining Techniques
Authors: Ko Hajung 
Published: December 2021

Abstract
Objectives: To distinguish between the differences in cultural services based on the type of urban green area, through atypical expressions.Context: Urban green spaces provide important ecosystem services, with cultural ecosystem services (CES) playing a significant role in citizens’ lives. Nevertheless, these are often undervalued as it is difficult to quantitatively evaluate the characteristics of an individuals’ subjective perception of urban space. By examining social media content, we can analyze the content created by users and grasp demand values. Methods: This study analyzed urban green areas in the inland of Ansan city in Gyeonggi-do, South Korea. Data were collected twice, on October 3, 2017 and October 4, 2018, to verify that the extracted keywords were representative. We extracted keywords from blog posts related to CES and evaluated the possibility of using them as quantitative indicators. Results: The results indicate that the perceived expression words were different depending on the type of green space. Certain CES such as “exhibit” and “climbing” are affected by green space type. However, it was difficult to identify emotional responses to CES. We found that some words contained double meanings, which made it difficult to evaluate individuals’ perceptions of CES based on the frequency of specific words.Conclusions: This study demonstrates that social media data on CES greatly extends the type and, especially, the volume and scale of information derived from traditional survey methods. The significance of this study lies in its attempt to quantitatively evaluate the recognition of CES in daily life.
Application of Binomial Models on the Determinants of Hypertension Patients in Haramaya Woreda, Eastern Hararghe, Ethiopia
Authors: Kebede Kindu , Mohammed Murad , Wesenu Million 
Published: December 2021

Abstract
Introduction: Hypertension is along with a medical condition, in which the blood pressure in the arteries is high, which is a major health problem in the community. The main aim of the study was to assess the determinants associated with patients who experienced hypertension in Haramaya Woreda using a binomial model. Methods: A cross-sectional study design was conducted to assess the associated factors of hypertension patients’ complications in the Haramaya Hospital, Eastern Hararghe zone from December 1st to 30th, 2020. Data were statistically analyzed using the statistical package for social sciences (SPSS) version-23 (SPSS Inc., USA). A sample of 1417 respondents having hypertension chronic disease was included. Statistical tools such as descriptive statistics, chi-square test of association, and binomial regression were used to summarize and interpret the hypertension patients’ dataset and a 5% level of significance was also used as a baseline comparison. Results: Both chi-square test of association and binomial model revealed that age group, gender, residence, presence of diabetes mellitus and congestive heart failure were significantly associated with hypertension patients at a 5% level of significance. Multivariable binomial regression model indicated that an estimated odd ratio(OR) with 95% confidence interval were age group of 21-30year3.502(95%CI=1.310-9.361),31-40year6.108(95%CI=2.364-15.782),41-50year 11.070(95%CI=4.276-28.661), 51-60 year 12.530(95% CI=4.890-32.107) and greater than 60 years 12.713(95%CI=4.827-33.482), being male (OR=1.859; 95%CI=1.320-2.617), living in rural (OR=0.545. 95%CI=0.381-0.778).The presence of diabetes mellitus (OR=0.028, 95%CI=0.019-0.040), and congestive heart failure (OR=0.017, 95%CI=0.009-0.032) are associated risk factors of hypertension patients. Conclusions: The main hypertension risk factors were age category, gender, residence, having diabetes mellitus, and congestive heart failure (p=0.0001). Those were significantly associated with hypertension in both the chi-square test of association and binomial model. To predict the participants being a hypertensive binomial model with logit link function best fit the dataset.
Centering Racial and Ethnic Equity in Health Care Throughout Spatial Data Analysis
Authors: Bell Nathaniel , Cai Bo , Brooks John , Lòpez-DeFede Ana 
Published: December 2021

Abstract
BackgroundThe ongoing COVID-19 pandemic as well as a host of social movements have put a nation-sized spotlight on structural inequality and racial disparities in health throughout America. As health care systems begin to advance health equity by holding plans and payers accounting for racial and socioeconomic disparities in care, quantitative methods are needed that emphasize the distinct linkages between physical locations and racially disparate outcomes.MethodsWe apply a counterfactual model to compare differences in avoidable and potentially avoidable emergency department (ED) admissions among a panel of 8,924 non-Hispanic White, Black, and Hispanic Medicaid participants between 2016 - 2018. The magnitude of disparity estimates is examined in relation to geographic proximity to health care providers, neighborhood socioeconomic contexts, as well as the type of primary care delivery model individuals received. The adjusted rates were assessed by generalized estimating equations (GEE) and average marginal effects models to contrast differences in probability of events in association with race/ethnicity, proximity to care, and treatment through patient-centered medical homes (PCMH). ResultsAttending a patient-centered medical home was associated with a 3.4 percentage point (p <0.001) decrease in Black-White racial disparity and a 1.8 percentage point (p < 0.10) reduction in the overall Black-White disparity for potentially avoidable ED admissions. PCMH attendance was attributed to a 2.6 percentage point (p < 0.10) reduction in Hispanic-White disparities in potentially avoidable admissions, but this difference was not substantial enough to curb the overall Hispanic-White racial disparity in ED admissions. No statistically significant reductions in Black-White or Hispanic-White disparities in avoidable ED admissions were observed. ConclusionMedical homes may be able to curb, but not necessarily eliminate, racial disparities in ED admissions. Counterfactual models of health disparities are in line with recent transitions toward evaluating patient- and value-centered health care reform changes as they are designed to measure health and racial equity. This strategy, or variations of it, are adaptable to other investigations where emphasis on physical locations is considered essential to understanding racial disparities in health outcomes.
Metal Contamination of Canal Versus Sewage Water Irrigated Vegetables in Metropolitan Area of Sargodha, Pakistan
Authors: Shahzad Ahsan , Ahmad Hamaad Raza , Farooqi Zia Ur Rahman , Sabir Muhammad , Ayub Muhammad Ashar , Ilic Predrag , Tariq Sanaullah 
Published: December 2021

Abstract
The reduction in the fresh water supply and increase in the domestic effluents with increase in population and urbanization in the Pakistan force the farmers to use untreated sewage water for the irrigation purposes. Besides high nutrient content Sewage water also have source of metal contamination in the food chain. The present field study was conducted to compare the nickel (Ni), copper (Cu) and lead (Pb) contamination in vegetables grown on soils irrigated with sewage water and canal water in Sargodha, Punjab, Pakistan. The Ni, Cu and Pb contamination was assessed using soil quality indices i.e., contamination factor (CF), metal translocation factor (MTF), pollution load index (PLI), geo-accumulation index (Igeo) and ecological risk index (ERI) were calculated in the collected samples. The physico-chemical properties of soil and water samples were determined. Based on the results, it was revealed that sewage irrigated areas were at higher risks of metals contamination compared to canal irrigated areas. From the studied metals, Pb showed highest contamination potential based on the soil quality indices. In sewage irrigated sites, metal concentrations were found higher in edible parts of the vegetables confirming that sewage water contains and supply more metals than canal irrigated water and pose more health and ecological risks.
Adolescent Perspectives on Participating in a Feasibility Trial Investigating Shoe Inserts for Patellofemoral Pain
Authors: O’Sullivan Isobel C. , Costa Nathalia , Smith Melinda M Franettovich , Vicenzino Bill , Crossley Kay M , Kamper Steven J , Middelkoop Marienke van , Menz Hylton B , Tucker Kylie , O'Leary Karina T , Collins Natalie J 
Published: December 2021

Abstract
Background

Patellofemoral pain (PFP) affects one-quarter of adolescents, yet there are few evidence-informed recommendations to treat PFP in this population. HAPPi Kneecaps! is a randomised, controlled, participant- and assessor-blind, parallel-group feasibility trial of shoe inserts for adolescents with PFP. The aim of this qualitative study was to explore adolescents’ perspectives of participating in HAPPi Kneecaps!.
Methods

All 36 adolescents with PFP from the HAPPi Kneecaps! study were invited to participate in semi-structured interviews. We used a descriptive qualitative methodology underpinned by a relativist framework to investigate adolescents’ perspectives on participating in the trial. Inductive thematic analysis was used to examine patterns regarding how each adolescent experienced the HAPPi Kneecaps! study within their social, cultural, and historical contexts.
Results

14 out of 36 HAPPi Kneecaps! participants provided consent and participated in interviews (12 females; mean [SD] age 14.9 [2.4] years). Overall, most adolescents responded positively when discussing their experience, such as improvements in their knee pain and satisfaction with how the study was run. Major themes emerging from the analysis and feedback were: (1) shoe inserts require little effort to use; (2) shoe inserts improve symptoms and function; (3) participation in the trial could be made easier; (4) warm weather matters; and (5) life happens.
Conclusion

Adolescents with PFP who participated in the HAPPi Kneecaps! study found that shoe inserts were easy to wear. Most adolescents experienced an improvement in their symptoms and enhanced participation in sport and exercise. Adolescents with PFP prefer an option for warmer climates (e.g. flip flops or sandals), access to online logbooks, and clinicians who are easily accessible.
Trial registration:

Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12619000957190. Date registered: 8/07/2019.
Perceived Stress, Psychological Capital, and Psychological Distress Among Chinese Nursing Students: A Cross-Sectional Study
Authors: Sun Feifei , Xu Cuiping , Xue Jiaomei , Su Jing , Lu Qinghua , Wang Bin 
Published: December 2021

Abstract
Background: Previous studies have investigated variables related to psychological distress among nurses; however, the relationship among psychological capital, perceived stress, and psychological stress is poorly understood. This cross-sectional study examined the relationship between psychological capital, psychological distress, and perceived stress, and examined the mediating role of psychological capital in the relationship between perceived stress and psychological distress.Methods: Responses to questionnaires to assess psychological capital, psychological distress, and perceived stress were collected from 369 nursing students in a tertiary hospital in Shandong Province, China.Results: There was a statistically significant difference in perceived stress among students, based on whether or not they liked the nursing profession (P<0.01). Relative to college students, undergraduates experienced significantly higher levels of perceived stress (P<0.01). Nevertheless, there were no significant differences in perceived stress between the variables of gender, place of residence, and being an only child. Psychological distress was positively correlated (r=0.632, p<0.001), whereas psychological capital was negatively correlated, with perceived stress (r=-0.662, p<0.001). Psychological capital played a potential mediating role in the relationship between psychological distress and perceived stress.Conclusions: This study revealed the importance of psychological capital in reducing perceived stress to decrease psychological distress among Chinese nursing students. Managers should take meaningful steps to improve nursing students’ psychological capital and thereby reduce the negative impact of psychological distress.
Camptothecin-Carrying Cuco2s4 Nanoparticles: Sustained Drug Release And Anticancer Activity
Authors: Pillai Archana Sumohan , Alexander Aleyamma , Manikantan Varnitha , Varalaks Govindaraj Sri , Akash Bose Allben , Enoch Israel V M V 
Published: December 2021

Abstract
Nanocarriers of anticancer drugs are delicately designed with precision addition at every attempt. In this paper, we report CuCo2S4 nanoparticles that show light-absorption in the NIR-II wavelength range and possess magnetic characteristics. The synthesized nanoparticles are characterized employing XRD, SEM, DLS, TGA, and XPS methods. The nanoparticles form a composite with biocompatible polymeric β-cyclodextrin. The nanoparticles possess a band gap energy of 2.25 eV. The magnetic property arises due to the cobalt-incorporation in the nanoparticles. The anticancer drug, camptothecin, is loaded in the nanocarrier with an 89% adsorption efficiency. The in vitro release of the drug occurs in a sustained fashion. Further, the in vitro anticancer potential of the nanocarrier is examined on breast cancer (MDA=MB-231) cell lines and the activities of the free- and the drug-loaded nanocarrier are compared. The cobalt-containing copper sulfide nanoparticle-poly-β-cyclodextrin composite works as a promising nanocarrier of camptothecin.
A Significance of Land Cover - Why Wisents Succeed to Outlive Aurochs?
Authors: Augustyn M. , Perzanowski Kajetan 
Published: December 2021

Abstract
Context Two native European large herbivores: the aurochs (Bos primigenius) and the wisent (Bison bonasus) lived simultaneously until late Medieval Ages. A rapid decline of aurochs occurred between XV and VII centuries, while wisents lived in the wild until early XX century. Aurochs went extinct despite their strict protection, imposed by Polish kings. Since XV century, radical changes in land cover occurred all over Europe, which could influence the survival of those species. Objectives We aimed to present differences in geographical distribution and occurrence of aurochs and wisents, and identify major changes in land cover of Europe since Medieval Ages. Considering those, we were trying to explain differences in the survival of so closely related and biologically similar species. Methods We compared distribution and incidence of traditional geographical names associated with both species in central-eastern Europe, with historical changes in land cover there. Considering biological differences between aurochs and wisents we attempted to identify possible reasons for such difference in their survival. Results Since aurochs were predominantly true grazers, having higher preference towards open landscapes, they apparently were stronger affected by the loss of suitable habitats due to the development of agriculture. Wisents being more flexible could survive in forests avoiding encounters and conflicts with people. Conclusions Changes in land cover may be critical for the survival of endangered species, even strictly protected. This issue has to be seriously considered in nature conservation planning and in the evaluation of habitat quality for wildlife.
Different Estradiol Level's Impact on Appetite Regulation, Food Intake, and Concentrations of Leptin, Glucagon-Like Peptide-1, and High-Sensitivity C-Reactive Protein During a Long Agonist IVF Protocol
Authors: Leppänen Jonna , Nuotio Petrus , Randell Kaisa , Romppanen Jarkko , Keski-Nisula Leea , Laitinen Tomi , Pihlajamäki Jussi , Schwab Ursula , Heinonen Seppo 
Published: December 2021

Abstract
Background: Do different hormonal phases affect appetite regulation, food intake, and concentrations of leptin, glucagon-like peptide-1 (GLP-1), and high-sensitivity C-reactive protein (hs-CRP) during a long agonist in vitro fertilization (IVF) protocol? Does the IVF stimulation induce metabolic changes, which might impact maternal health? Methods: Fifty-four infertile women were encountered thrice, the first of which was at the beginning of their period (low estradiol). The other two were during a gonadotrophin-releasing hormone (GnRH) analog downregulation (low estradiol) and at the end of a follicle-stimulating hormone (FSH) stimulation (high estradiol). The first visit was the reference; the women served as their controls. The concentrations of leptin, GLP-1, and hs-CRP were assessed from plasma. Dietary intake was assessed using food records (FRs) three days before each visit. In addition, weight, height, body mass index (BMI), and plasma levels of estradiol, glucose, HbA1c, insulin, and lipids were monitored. Twenty-six of the subjects also had a postprandial test, in which the blood samples were taken at five time points at every three visits. They also filled visual analog scales to exhibit satiety and appetite. Twenty-eight of the subjects had only fasting blood samples. Results: During the stimulation protocol, leptin concentrations elevated (P<0.001), and energy intake decreased (P=0.03) while estradiol levels increased (P<0.001). GLP-1 levels unchanged (P=0.75) and hs-CRP (P=0.03) concentrations diminished while estradiol levels increased. Conclusions: No increased food intake or weight gain occurred during the stimulation protocol; thus, leptin may protect from overeating during high estradiol levels, and leptin resistance may not occur during a short follow-up. Also, a favorable anti-inflammatory effect was detected. During this study, no harmful metabolic effects occurred, which might have a disproportionate impact on maternal health. Trial registration: Not applicable. This study is a clinical study without intervention.
Chronic Postsurgical Pain After Minimally Invasive Adrenalectomy: Prevalence and Impact on Quality of Life
Authors: Helden Esmee V. van , Uitert Allon van , Albers Kim I. , Steegers Monique A.H. , Timmers Henri J.L.M. , d'Ancona Frank C.H. , Wal Selina E.I. van der , Scheffer Gert-Jan , Keijzer Christiaan , Warlé Michiel C. , Langenhuijsen Johan F. 
Published: December 2021

Abstract
Background.

Minimally invasive adrenalectomy is the standard of care for small adrenal tumours. Both the transperitoneal lateral approach and posterior retroperitoneal approach are widely used and have been proven to be safe and effective. However, the prevalence of chronic postsurgical pain has not been specifically investigated in previous studies. The primary goal of this study was to identify the prevalence of chronic postsurgical pain after minimally invasive adrenalectomy.
Methods.

A cross-sectional study was performed among all consecutive patients who had undergone minimally invasive adrenalectomy in a single university medical centre. The primary outcome was the prevalence of chronic postsurgical pain. Secondary outcomes were the prevalence of localized hypoesthesia, risk factors for the development of chronic postsurgical pain, and the Health-Related Quality of Life. Three questionnaires were used to measure the prevalence and severity of chronic postsurgical pain, hypoesthesia, and Health-Related Quality of Life. Logistic regression analysis was performed to determine risk factors for development of chronic postsurgical pain.
Results.

Six hundred two patients underwent minimally invasive adrenalectomy between January 2007 and September 2019, of whom 328 signed informed consent. The prevalence of chronic postsurgical pain was 14.9%. Young age was a significant predictor for developing chronic postsurgical pain. The prevalence of localized hypoesthesia was 15.2%. In patients with chronic postsurgical pain, Health-Related Quality of Life was significantly lower, compared to patients without pain.
Conclusions.

The prevalence of chronic postsurgical pain following minimally invasive adrenalectomy is considerable. Furthermore, the presence of chronic postsurgical pain was correlated with a significant and clinically relevant lower Health-Related Quality of Life. These findings should be included in the preoperative counselling of the patient. In the absence of evidence for effective treatment in established chronic pain, prevention should be the key strategy and topic of future research.
The Influence of Anaesthetic Choice on Electroconvulsive Therapy Parameters; Etomidate Versus Methohexital
Authors: Chomrikh¹ Laila , Ahmadi Mustafa , Kuijper Martijn , Vlugt Joris J.B. Van der , Koopman Seppe J.H.A. 
Published: December 2021

Abstract
Background

Many of the anaesthetic drugs used for electroconvulsive therapy have anticonvulsant properties and may influence efficacy of electroconvulsive therapy. With this study we aim to provide more information on the effect of etomidate and methohexital on seizure duration. We explore the relationship between induction drug, motor and electroencephalography seizure duration. Moreover, we study the relationship of seizure duration and number of therapies.
Methods

In this retrospective study we collected data from patient records from 2005 until 2016. Inclusion criteria were the use of etomidate and/or methohexital and documentation of dosage, electroconvulsive therapy dosage and seizure duration. Exclusion criteria were missing data on either induction drug, dosage or seizure duration.
Results

Thirty seven patients were analysed. The mean age was 52 years and seventy six percent were female. Most patients were suffering from affective disorders (81%). Motor and electroencephalography seizure duration were analysed in 679 and 551 electroconvulsive therapies, respectively. Compared to methohexital, motor and electroencephalography seizures under etomidate were 7 and 13 seconds longer, respectively. Furthermore, there was a negative association between seizure duration and number of treatment and a negative association between seizure duration and electroconvulsive therapy dosage.
Conclusions

This study demonstrates significant longer motor and electroencephalography seizure duration using etomidate compared to methohexital. Etomidate might therefore increase the effectiveness of electroconvulsive therapy. Moreover, we observed a negative association between seizure duration, number of treatment and electroconvulsive therapy dosage. With this study we contribute to the available literature comparing methohexital and etomidate as induction agents for electroconvulsive therapy.