bluuebunny/crossref_metadata_2025_split huggingface dataset:
Weight-based stereotype threat in the workplace: consequences for employees with overweight or obesity
Authors: Zacher Hannes , von Hippel Courtney 
Published: December 2021

Abstract
Background/Objectives
Employees with overweight or obesity are often stereotyped as lazy, unmotivated, and less competent than employees with normal weight. As a consequence, employees with overweight or obesity are susceptible to stereotype threat, or the concern about confirming, or being reduced to, a stereotype about their group. This survey study examined whether employees with overweight or obesity experience stereotype threat in the workplace, whether it is associated with their perceived ability to meet their work demands (i.e., work ability), and whether high levels of knowledge about one’s self (i.e., authentic self-awareness) can offset a potential negative association.

Subjects/Methods
Using a correlational study design, survey data were collected from N = 758 full-time employees at three measurement points across 3 months. Employees’ average body mass index (BMI) was 26.36 kg/m² (SD = 5.45); 34% of participants were employees with overweight (BMI between 25 and <30), and 18% of participants were employees with obesity (BMI > 30).

Results
Employees with higher weight and higher BMI reported more weight-based stereotype threat (rs between 0.17 and 0.19, p < 0.001). Employees who experienced higher levels of weight-based stereotype threat reported lower work ability, while controlling for weight, height, and subjective weight (β = −0.27, p < 0.001). Authentic self-awareness moderated the relationship between weight-based stereotype threat and work ability (β = 0.14, p < 0.001), such that the relationship between stereotype threat and work ability was negative among employees with low authentic self-awareness (β = −0.25, p < 0.001), and non-significant among employees with high authentic self-awareness (β = 0.08, p = 0.315).

Conclusions
The findings of this study contribute to the literature by showing that weight-based stereotype threat is negatively associated with employees’ perceived ability to meet their work demands, particularly among those employees with low authentic self-awareness.
TMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early chondrocyte differentiation and hypertrophy
Authors: Khan Sajida , Sbeity Malak , Foulquier François , Barré Lydia , Ouzzine Mohamed 
Published: December 2021

AbstractTMEM165 deficiency leads to skeletal disorder characterized by major skeletal dysplasia and pronounced dwarfism. However, the molecular mechanisms involved have not been fully understood. Here, we uncover that TMEM165 deficiency impairs the synthesis of proteoglycans by producing a blockage in the elongation of chondroitin-and heparan-sulfate glycosaminoglycan chains leading to the synthesis of proteoglycans with shorter glycosaminoglycan chains. We demonstrated that the blockage in elongation of glycosaminoglycan chains is not due to defect in the Golgi elongating enzymes but rather to availability of the co-factor Mn2+. Supplementation of cell with Mn2+ rescue the elongation process, confirming a role of TMEM165 in Mn2+ Golgi homeostasis. Additionally, we showed that TMEM165 deficiency functionally impairs TGFβ and BMP signaling pathways in chondrocytes and in fibroblast cells of TMEM165 deficient patients. Finally, we found that loss of TMEM165 impairs chondrogenic differentiation by accelerating the timing of Ihh expression and promoting early chondrocyte maturation and hypertrophy. Collectively, our results indicate that TMEM165 plays an important role in proteoglycan synthesis and underline the critical role of glycosaminoglycan chains structure in the regulation of chondrogenesis. Our data also suggest that Mn2+ supplementation may be a promising therapeutic strategy in the treatment of TMEM165 deficient patients.
BNIP3L/NIX-mediated mitophagy: molecular mechanisms and implications for human disease
Authors: Li Yue , Zheng Wanqing , Lu Yangyang , Zheng Yanrong , Pan Ling , Wu Xiaoli , Yuan Yang , Shen Zhe , Ma Shijia , Zhang Xingxian , Wu Jiaying , Chen Zhong , Zhang Xiangnan 
Published: December 2021

AbstractMitophagy is a highly conserved cellular process that maintains the mitochondrial quantity by eliminating dysfunctional or superfluous mitochondria through autophagy machinery. The mitochondrial outer membrane protein BNIP3L/Nix serves as a mitophagy receptor by recognizing autophagosomes. BNIP3L is initially known to clear the mitochondria during the development of reticulocytes. Recent studies indicated it also engages in a variety of physiological and pathological processes. In this review, we provide an overview of how BNIP3L induces mitophagy and discuss the biological functions of BNIP3L and its regulation at the molecular level. We further discuss current evidence indicating the involvement of BNIP3L-mediated mitophagy in human disease, particularly in cancer and neurological disorders.
MYCL promotes iPSC-like colony formation via MYC Box 0 and 2 domains
Authors: Akifuji Chiaki , Iwasaki Mio , Kawahara Yuka , Sakurai Chiho , Cheng Yu-Shen , Imai Takahiko , Nakagawa Masato 
Published: December 2021

AbstractHuman induced pluripotent stem cells (hiPSCs) can differentiate into cells of the three germ layers and are promising cell sources for regenerative medicine therapies. However, current protocols generate hiPSCs with low efficiency, and the generated iPSCs have variable differentiation capacity among different clones. Our previous study reported that MYC proteins (c-MYC and MYCL) are essential for reprogramming and germline transmission but that MYCL can generate hiPSC colonies more efficiently than c-MYC. The molecular underpinnings for the different reprogramming efficiencies between c-MYC and MYCL, however, are unknown. In this study, we found that MYC Box 0 (MB0) and MB2, two functional domains conserved in the MYC protein family, contribute to the phenotypic differences and promote hiPSC generation in MYCL-induced reprogramming. Proteome analyses suggested that in MYCL-induced reprogramming, cell adhesion-related cytoskeletal proteins are regulated by the MB0 domain, while the MB2 domain regulates RNA processes. These findings provide a molecular explanation for why MYCL has higher reprogramming efficiency than c-MYC.
Evaluation of reverse transcription-loop-mediated isothermal amplification for rapid detection of SARS-CoV-2
Authors: Quino Willi , Flores-León Diana , Caro-Castro Junior , Hurtado Carmen V. , Silva Iris , Gavilan Ronnie G. 
Published: December 2021

AbstractThe main strategy for response and control of COVID-19 demands the use of rapid, accurate diagnostic tests aimed at the first point of health care. During the emergency, an increase in asymptomatic and symptomatic cases results in a great demand for molecular tests, which is promoting the development and application of rapid diagnostic technologies. In this study, we describe the development and evaluation of RT-LAMP to detect SARS-CoV-2 based on three genes (ORF1ab, M and N genes) in monoplex and triplex format. RT-LAMP assays were compared with the gold standard method RT-qPCR. The triplex format (RdRp, M and N genes) allowed obtaining comparable results with de RT-qPCR (RdRp and E genes), presented a sensitivity of 98.9% and a specificity of 97.9%, opening the opportunity to apply this method to detect SARS-CoV-2 at primary health-care centers.
Estimated plasma volume status is a modest predictor of true plasma volume excess in compensated chronic heart failure patients
Authors: Ahlgrim Christoph , Birkner Philipp , Seiler Florian , Grundmann Sebastian , Bode Christoph , Pottgiesser Torben 
Published: December 2021

AbstractPlasma volume and especially plasma volume excess is a relevant predictor for the clinical outcome of heart failure patients. In recent years, estimated plasma volume based on anthropometric characteristics and blood parameters has been used whilst direct measurement of plasma volume has not entered clinical routine. It is unclear whether the estimation of plasma volume can predict a true plasma volume excess. Plasma volume was measured in 47 heart failure patients (CHF, 10 female) using an abbreviated carbon monoxide rebreathing method. Plasma volume and plasma volume status were also estimated based on two prediction formulas (Hakim, Kaplan). The predictive properties of the estimated plasma volume status to detect true plasma volume excess > 10% were analysed based on logistic regression and receiver operator characteristics. The area under the curve (AUC) to detect plasma volume excess based on calculation of plasma volume by the Hakim formula is 0.65 (with a positive predictive value (PPV) of 0.62 at a threshold of − 16.5%) whilst the AUC for the Kaplan formula is 0.72 (PPV = 0.67 at a threshold of − 6.3%). Only the estimated plasma volume status based on prediction of plasma volume by the Kaplan formula formally appears as an acceptable predictor of true plasma volume excess, whereas calculation based on the Hakim formula does not sufficiently predict a true plasma volume excess. The low positive predictive values for both methods suggest that plasma volume status estimation based on these formulas is not suitable for clinical decision making.
Unorthodox cascade reaction of arynes and N-nitrosamides leading to indazole scaffolds
Authors: Sureshbabu Popuri , Bhajammanavar Vinod , Choutipalli Venkata Surya Kumar , Subramanian Venkatesan , Baidya Mahiuddin 
Published: December 2021

A cascade annulation of arynes with N-alkyl-N-nitrosamides is developed by leveraging aryne σ-insertion and C(sp3)–H bond functionalization strategies under transition-metal-free conditions to access indazoles in high yields and regioselectivity.
Intraoperative Spinal Angiography during Microsurgical Occlusion of Spinal Dural Arteriovenous Fistula within the Hybrid Operation Room
Authors: Kienzler Jenny Christine , Schoepf Salome , Marbacher Serge , Diepers Michael , Remonda Luca , Fandino Javier 
Published: December 2021

AbstractBackground Spinal dural arteriovenous fistula (SDAVF) is a rare cause of progressive myelopathy in predominantly middle-aged men. Treatment modalities include surgical obliteration and endovascular embolization. In surgically treated cases, failure of obliteration is reported in up to 5%. The aim of this technical note is to present a safe procedure with complete SDAVF occlusion, verified by intraoperative digital subtraction angiography (DSA).Methods We describe four patients with progressive leg weakness who underwent surgical obliteration of SDAVF with spinal intraoperative DSA in the prone position after cannulation of the popliteal artery. All surgeries took place in our hybrid operating room (OR) and were accompanied by electrophysiologic monitoring. Surgeries and cannulation of the popliteal artery were performed in the prone position. Ultrasound was used to guide the popliteal artery puncture. A 5-Fr sheath was inserted and the fistula was displayed using a 5-Fr spinal catheter. Spinal intraoperative DSA was performed prior to and after temporary clipping of the fistula point as well after the final SDAVF occlusion.Results The main feeder of the SDAVF fistula in the first patient arose from the right T11 segmental artery, which also supplied the artery of Adamkiewicz. The second patient initially underwent endovascular treatment and deteriorated 5 months later due to recanalization of the SDAVF via a small branch of the T12 segmental artery. The third and fourth cases were primarily scheduled for surgical occlusion. Access through the popliteal artery for spinal intraoperative DSA proved to be beneficial and safe in the hybrid OR setting, allowing the sheath to be left in place during the procedure. During exposure and after temporary and permanent occlusion of the fistulous point, intraoperative indocyanine green (ICG) video angiography was also performed. In one case, the addition of intraoperative DSA showed failure of fistula occlusion, which was not visible with ICG angiography, leading to repositioning of the clip. Complete fistula occlusion was documented in all cases.Conclusion Spinal intraoperative DSA in the prone position is a feasible and safe intervention for rapid localization and confirmation of surgical SDAVF occlusion.
Development of high-resolution capacitive Faraday magnetometers for sub-Kelvin region
Authors: Shimizu Yusei , Kono Yohei , Sugiyama Tomoyoshi , Kittaka Shunichiro , Shimura Yasuyuki , Miyake Atsushi , Aoki Dai , Sakakibara Toshiro 
Published: December 2021

High-sensitivity capacitive Faraday magnetometers were developed for static DC magnetization measurements in a sub-Kelvin region that can be used with 3He–4He dilution refrigerators (∼50 mK) and 3He refrigerators (∼0.28 K). For high-resolution magnetization measurements, the background magnetization of the force-sensing capacitor should be as small as possible, compared with the magnetization value of a measured specimen. In this study, we succeeded in reducing the background of the capacitor in both low- and high-field regions by compensating for the diamagnetic response of a thin quartz plate, making use of Pauli-paramagnetic alloys and Van Vleck paramagnets as a counter magnetization for a diamagnetic signal. Having established an ultra-high-sensitivity capacitor, we achieved a resolution of 10−5 (∼10−5–10−6) emu in the low- (high-) field region below (above) 1 T. In particular, the newly developed capacitors with a Van Vleck paramagnet Pr0.1La0.9Be13 and paramagnetic MgAl alloys are demonstrated to be very useful for high-resolution magnetization measurements at milli-Kelvin temperatures in low and high magnetic fields, respectively.
De novo mutations in childhood cases of sudden unexplained death that disrupt intracellular Ca
2+
regulation
Authors: Halvorsen Matthew , Gould Laura , Wang Xiaohan , Grant Gariel , Moya Raquel , Rabin Rachel , Ackerman Michael J. , Tester David J. , Lin Peter T. , Pappas John G. , Maurano Matthew T. , Goldstein David B. , Tsien Richard W. , Devinsky Orrin 
Published: December 2021

Significance
Approximately 400 United States children 1 y of age and older die suddenly from unexplained causes annually. We studied whole-exome sequence data from 124 “trios” (decedent child and living parents) to identify genetic risk factors. Nonsynonymous mutations, mostly de novo (present in child but absent in both biological parents), were highly enriched in genes associated with cardiac and seizure disorders relative to controls, and contributed to 9% of deaths. We found significant overtransmission of loss-of-function or pathogenic missense variants in cardiac and seizure disorder genes. Most pathogenic variants were de novo in origin, highlighting the importance of trio studies. Many of these pathogenic de novo mutations altered a protein network regulating calcium-related excitability at submembrane junctions in cardiomyocytes and neurons.
Toumeyella parvicornis
. [Distribution map].
Authors: CABI  , EPPO  
Published: December 2021

Abstract

A new distribution map is provided for
Toumeyella parvicornis
(Cockerell). Hemiptera: Coccidae. Hosts:
Pinus
spp. Information is given on the geographical distribution in Europe (France, Italy), North America (Canada, Manitoba, Ontario, Quebec, Mexico, Puerto Rico, Turks and Caicos Islands, United States (Alabama, Colorado, District of Columbia, Florida, Georgia, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maryland, Massachusetts, Michigan, Minnesota, Nebraska, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Virginia, West Virginia, Wisconsin)).
Spectroscopic analysis of M- and N-intrashell transitions in Co-like to Na-like Yb ions
Authors: Silwal Roshani , Dipti Dipti , Takacs Endre , Dreiling Joan M. , Sanders Samuel C , Gall Amy Christina , B Hemalatha Rudramadevi , Gillaspy John D , Ralchenko Yuri 
Published: December 2021

Abstract
The M-intrashell spectra from Co-like Yb43+ through Na-like Yb59+ ions produced in an electron beam ion trap (EBIT) at the National Institute of Standards and Technology have been studied in the extreme ultraviolet (EUV) range. A few N-intrashell transitions for Co-like Yb43+ and Fe-like Yb44+ are also reported. The EUV radiation was observed with a ﬂat-ﬁeld grazing incidence spectrometer in the wavelength region of about 7.5 nm to 26.2 nm. The electron beam energies were varied between 3.6 keV and 18 keV to produce the ionization stages of interest. The line identiﬁcations were based on the large-scale simulations of the EBIT plasma emission using the non-Maxwellian collisional-radiative code NOMAD. A total of 76 previously unobserved spectral lines corresponding to electric-dipole and magnetic-dipole transitions in the above mentioned ions were identiﬁed and discussed. In particular, our accurate wavelength of 24.3855±0.0005 nm for a magnetic-dipole (M1) transition in the ground conﬁguration of Co-like ion presents a solid benchmark for comparisons with the most advanced theories of atomic structure.
Majorana/Andreev crossover and the fate of the topological phase transition in inhomogeneous nanowires
Authors: Marra Pasquale , Nigro Angela 
Published: December 2021

Abstract
Majorana bound states (MBS) and Andreev bound states (ABS) in realistic Majorana nanowires setups have similar experimental signatures which make them hard to distinguishing one from the other. Here, we characterize the continuous Majorana/Andreev crossover interpolating between fully-separated, partially-separated, and fully-overlapping Majorana modes, in terms of global and local topological invariants, fermion parity, quasiparticle densities, Majorana pseudospin and spin polarizations, density overlaps and transition probabilities between opposite Majorana components. We found that in inhomogeneous wires, the transition between fully-overlapping trivial ABS and nontrivial MBS does not necessarily mandate the closing of the bulk gap of quasiparticle excitations, but a simple parity crossing of partially-separated Majorana modes (ps-MM) from trivial to nontrivial regimes. We demonstrate that fully-separated and fully-overlapping Majorana modes correspond to the two limiting cases at the opposite sides of a continuous crossover: the only distinction between the two can be obtained by estimating the degree of separations of the Majorana components. This result does not contradict the bulk-edge correspondence: indeed, the field inhomogeneities driving the Majorana/Andreev crossover have a length scale comparable with the nanowire length, and therefore correspond to a nonlocal perturbation which breaks the topological protection of the MBS.
Binary Bose–Einstein condensates in a disordered time-dependent potential
Authors: Abbas Karima , Boudjemâa Abdelâali 
Published: December 2021

Abstract
We study the non-equilibrium evolution of binary Bose–Einstein condensates in the presence of a weak random potential with Gaussian correlation function using the time-dependent perturbation theory. We apply this theory to construct a closed set of equations that highlight the role of the spectacular interplay between the disorder and the interspecies interactions in the time evolution of the density induced by disorder in each component. It is found that this latter increases with time favoring localization of both species. The time scale at which the theory remains valid depends on the respective system parameters. We show analytically and numerically that such a system supports a steady state that periodically changing during its time propagation. The obtained dynamical corrections indicate that disorder may transform the system into a stationary out-of-equilibrium states. Understanding this time evolution is pivotal for the realization of Floquet condensates.
Silicene dynamic optical response in the presence of external electric and exchange fields
Authors: Mirzaei M , Vazifehshenas T , Salavati-fard T , Tanatar B 
Published: December 2021

Abstract
We investigate the dynamic optical transition of monolayer silicene in the presence of external electric and exchange fields within the low-energy tight-binding model. Applying external electric and exchange fields breaks the silicene band structure spin and valley degeneracies. Three phases of silicene corresponding to different strengths of perpendicular electric field with respect to the spin–orbit coupling (Δ
z
< Δso, Δ
z
= Δso and Δ
z
> Δso) are considered. We obtain the spin-valley-dependent optical responses to the incoming circularly polarized light using the Kubo formula. We show and discuss how the magnitude and direction of the transverse and longitudinal optical responses of such a system change with the electric and exchange fields. Our calculations suggest that the intraband part of the longitudinal optical response as well as the initial point of the interband part have strong dependencies on the exchange field. Furthermore, we show that one of the spin subbands plays a dominant role in the response to polarized light. Depending on the type of incident light polarization, the dominant subband may change. Our results shed light on the relation between silicene dynamic optical responses and externally applied fields.
Mesoscopic scale simulation and wear investigation of self-lubricating fabric liner based on representative volume element
Authors: Xue Yahong , Wang Xudong , Yan Shicheng , Wang Jutao , Zhou Haibo 
Published: December 2021

Abstract
As the self-lubricating layer of self-lubricating spherical plain bearings, fabric liner shows obvious heterogeneous anisotropic characteristics, so it is a technical difficulty to predict its wear properties. In this paper, the continuous wear of self-lubricating fabric liner was simulated based on the mesoscopic scale wear model. The macroscopic wear properties of the fabric liner were characterized by establishing a representative volume element, and subsequently imposing periodic boundary restrictions on periodic surfaces. In order to avoid excessive mesh distortion, voxel grids meshing method was used, and then continuous wear of the heterogeneous material was realized by adjusting node coordinates and combining nodes. Detailed comparison between simulation prediction results and wear test data of fabric liner was made. The good correlation of the results confirmed that the mesoscopic scale wear model could be used in accurately predict the tribological performance of fabric composite.
Experimental study of charging of dust grains in the presence of energetic electrons
Authors: Paul R , Sharma G , Deka K , Adhikari S , Moulick R , Kausik S S , Saikia B K 
Published: December 2021

Abstract
The role of hot electrons in the charging of dust grains is investigated in a two temperature hydrogen plasma. A variety of dust particles are introduced into the system and secondary electron emission (SEE) from each of the dust types has been reported. A cylindrical Langmuir probe is used for determining the plasma parameters and a Faraday cup is connected to an electrometer in order to measure the dust current. The electrometer readings confirm the electron emission from the dust and SEE is observed from the tungsten dust in a low-pressure experimental plasma device for the first time.