bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transdermal Penetrating Peptide Conjugated Liposomes as Drug Delivery Carrier Comprising Macromolecules
Authors: Soo Hyeon Heo, Beom-Jin Lee, Moon Sam Shin Hyung Jun Lim, Jinseo Lee, Su In Park, 
Published: April 2021

: The aim of the study was to investigate a system using liposomes and cell penetrating peptides (CPP) for optimal transdermal delivery of macromolecules. Typical DOPE liposomes were prepared with lipid mixture (DOPE:PC:Chol = 1.5:1.5:2.0, molar ratio) and active materials (Rhodamine B; MW ~480 and Dextran-RITC; MW ~10,000). CPP-conjugated DOPE liposomescontaining active materials were prepared by conjugating the peptide to DOPE liposomes (DOPE:PC:Chol:DSPE-PEG-Mal = 1.5:1.1:2.0:0.2 or 0.4, molar ratio). Physical properties of both liposomes were evaluated, including particle size and zeta potential. The particle sizes of typical liposome and CPP-DOPE liposome were approximately 100 nm, and the zeta potential values of both liposomes were approximately -25mV and over +11mV respectively. Moreover, cellular uptake efficiency was assessed by flow cytometry (FACS). CPP-conjugated liposomes resulted higher cellular uptake efficiency compared to typical DOPE liposomes, showing higher fluorescent intensity in CPP-DOPE liposomes. In confocal laser scanning microscope (CLSM) studies, both cellular uptake and skin permeation were visually estimated. In the case of Rhodamine B, having a relatively small molecular weight,absorption into the cell was successful, and showed the highest rate of cellular uptake with CPP-DOPE liposomes. Dextran-RITC, a macromolecule with a relatively bigger molecular weight, showed similar results to Rhodamine B. In terms of skin permeation, CPP-DOPE liposomes containing Rhodamine B showed noticeable skin absorption after 4 and 18 hours, and the permeation range was wider and thicker than that with typical liposomes. For Dextran-RITC, with typical DOPE liposome, it was hardly permeable through the skin, but with CPP-DOPE liposomes, on the other hand, the skin permeations after 4 and 18 hours were remarkable. The improved cellular uptake and skin permeation of the CPP-conjugated liposomes are due to the cationic arginine-rich peptide. In vivo studies also proved that the CPP-conjugated liposomes are superior in depigmentation and anti-wrinkle studies than typical liposomes. These results demonstrate that the CPP-conjugated liposomes could also be effective for transdermal drug delivery of antioxidant and anti-aging therapeutics.
A Study on Stator Design for Electromagnetic Noise Reduction in Washing Machine Motor
Authors: Kim Kwangsoo 
Published: April 2021

Received:11 november 2020; Accepted: 27 December 2020; Published online: 05 April 2021
Abstract : For low cost, spoke type ferrite magnet motors with small air gap are using to washing machine. At that time, a noise problem occurs, so a design to reduce the noise is required. In the washing machine, set noise increased due to the reduction of air gap of motor at high speed spin mode. Not only the overall noise, but also the harmonics noises are greatly increased at set. As a result of set noise test and noise analysis through finite elements method, a stator tooth shoe shape in which the magnetic flux changes rapidly is cause of noise. Its shape creates many harmonics of load torque. The harmonics component of the load torque increases the overall noise of the set. The harmonics noise of the set has a large correlation with radial force component as well as the torque ripple. Especially, it is found that the harmonics noise of the set is related to harmonics component of load torque and the harmonics component of the radial force at stator tooth. The noise is reduced by applying the new design of stator tooth shoe that can minimize the change in magnetic flux through the noise cause analysis. Through this research, the harmonics noise as well as overall noise are reduced at small airgap motor. Therefore, it is possible to develop cost reduction motor for washing machine.
Evaluating Second Intermediate’s Arabic Language Textbook in the Light of Quality Standards of School Textbooks
Authors: Khdair Asst. Prof. Wisal Muayad 
Published: April 2021

The current study aims at (evaluating the second intermediate grade’s Arabic language textbook). To accomplish this aim, the researcher adopted the descriptive approach (survey). The population included second intermediate Arabic language teachers numbered (373) in the governorate of Babylon in the year 2018_2019. The research sample included (100) teachers, the researcher chose the study sample randomly to represent the study population. The tool of study was a questionnaire included the quality criteria of second intermediate grade Arabic language textbook which was prepared after referring to the subject relevant sources and the previous studies, also, the reliability of the questionnaire was proven reliable by displaying it to a committee of specialists in Methodology.
The questionnaire included (18) criterion, distributed on six fields which are : objectives, content, methods, activities and it’s aids, evaluation and language of the book and its artistic and printing output. After analyzing the results statistically by using weighted mean, standard deviation and weighed percentage with a 75% validity to evaluate the textbook. After consulting the committee, the researcher came to these results:

The book took the first place in its language and artistic printing output with a value of (3.339) weighted mean and (83.228%) weight percentage.
Methodology took the second place with a value of (3.119) weighted mean and (77.999%) weight percentage.
Evaluation took the third place with a value of (3.081) weighted mean and (77.031) weight percentage.

In the light of these results, the researcher reached to the conclusion that there is a variation in distributing the criteria in the textbook in its both parts, the first one of 9 parts and the second one of 7 parts.
Also, in light of the results, the researcher recommended to find a structured methodology to choose the subjects in the textbook according to textbook criteria.
To complement this study, the researcher suggested that the textbook should be submitted to comprehensive quality criteria.
School Counseling Skills Needed To Activate Distance Learning In Light Of Covid-19 Pandemic
Authors: S AL-halalmeh, 
Published: April 2021

The problem and the aim of the study: COVID-19 pandemic had affected all sectors including the educational sector. The educational system shifted from the traditional face to face teaching method to use online means in order to ensure the safety of the students and the social distancing. These changes also affected the roles of the educational members including the school counselors. Therefore, the study aims to investigate the school counseling skills needed in light of COVID-19.
Research Method: The study relied on the descriptive approach and administrated by a questionnaire to collect the data from the school counselors. The study sample consisted of (400) Jordanian schools counselors from both genders whom chosen randomly to respond to the study tool.
Results: The study found that the main required skills are the cognitive, emotional and humanitarian skills, professional and ethical skills, technical and electronic skills. The study found that the most needed counseling skills are similar to the traditional education, but due to the shift from the from face to face education to the distance education the most concentration will be on the counselors IT skills.
Organization of the Public Procurement System in Japan and the Possibility of Applying Experience in Russia
Authors: Fedorova I. Yu. , Pipiya Yu. S. 
Published: April 2021

Purpose:is to identify the features of the organization of the Japanese public procurement system and the applicability of the positive experience for Russia. For this, it is necessary to study the organization of the public procurement system in Japan, highlighting the most effective elements and tools; to show the features of the functioning of the system and possible ways of future development; to give a comparative description of the procurement systems of Japan and Russia; to suggest ways to improve the Russian procurement system, using the experience of Japan.Methods:during the work, general scientific and special research methods were used, including statistical analysis, processing of analytical data, analogies, scientific generalizations, etc.Results:as a result of the analysis of changes in the legislative framework, on the basis of which public procurement in Japan is regulated, the authors examined the qualitative characteristics of the interconnections of the procurement system participants and assessed the development prospects, incl. Special attention is paid to the content and hierarchy of regulatory legal acts regulating the scope of procurement.The important link of the author's research was the procedure for organizing procurement in the course of applying various types of procurement procedures, including open, selective and limited procurement methods. A comparative analysis of the procurement systems of Japan and the Russian Federation allowed us to determine the similarities and differences in the organization of the procurement process.Conclusions and Relevance: as a result of the analysis the validity of the execution of the state order through the competitive procurement system used in world practice has been substantiated. This formed the basis of the targeted approach and the identification of promising directions in the development of the public procurement system in Japan until 2030. The authors highlight the areas that are successfully implemented in the field of public procurement in the Russian Federation. This indicates the positive development of the Russian system, which was created taking into account the best international experience, including Japanese practice. To improve the mechanism of interaction between participants and exchange of experience in the public procurement system, directions have been identified and the most effective tools have been identified.
Financial Mechanism for the Development of Islamic Business in the Russian Federation
Authors: Youssef H.A. 
Published: April 2021

Purpose: in modern conditions in Russia there are regions with a large proportion of the Muslim population that implement initiatives for the development of Islamic business, however, the functioning Islamic business model practically does not differ from the traditional model of Russian entrepreneurship, only individual elements and principles, types and forms of entrepreneurial activity based on principles of Sharia, Islamic banking is being promoted more actively. In this regard, the purpose of this article is to study the financial mechanism for the development of Islamic business in the Russian Federation in the context of the implementation of key areas of state support for entrepreneurship at the federal and regional levels.Methods: the study is based on the use of general scientific methods of induction and deduction, a review of scientific sources; the quantitative assessment is based on the calculation of statistical indicators, in particular: the relative size of the structure of segments of the Islamic economy with comparative studies in the country context of the volume of the halal food market, chain and basic indicators of the series of dynamics of directions of state support for Islamic business and regional levels.Results: the article analyzes the main directions, tools and institutions for the implementation of state support for Islamic entrepreneurship in foreign practices, indicating the active development of legislative, regulatory and organizational infrastructure, large-scale financing of infrastructure support programs. The article also provides an analytical overview of the development of Islamic business in the Russian Federation. Particular attention in the article is paid to the analysis of federal and regional programs to support Islamic entrepreneurship, which made it possible to identify the features of the implementation of the mechanism of state support.Conclusions and Relevance: it has been determined that in Russia the most developed segments of Islamic entrepreneurship are the halal industry, the development of which is supported by state programs at the sub-federal level, and the relationship of partner banking. The factors that limit the development of Islamic entrepreneurship in the Russian Federation have been identified: inadequacy of federal programs for financing Islamic business; the local nature of support for Islamic entrepreneurs within the framework of regional programs («point» principle).
Impact and Consequences of the COVID-19 Pandemic: Socio-Economic Dimension
Authors: Shcherbakov G. A. 
Published: April 2021

Purpose: the active development of the coronavirus pandemic and measures to counter it by national authorities and international organizations have already influenced the perception of reality by the inhabitants of the planet. There is a natural desire to understand: everything that is happening is a temporary phenomenon, the overcoming of which will return our life to its former course, or the transformations taking place in society are of a long-term nature, and humanity is in the process of forming qualitatively new parameters of existence, which can become a "new normality". The main objective of the study is to conduct a qualitative analysis of changes in the socio-economic sphere associated with the spread of the COVID-19 pandemic in the world. The goal is to identify social, economic and institutional processes that can influence the life of society.Methods: a set of methods of practical analysis and theoretical research was used, including: logical, system and abstract methods.Results: the study solves the main task of this work - to conduct a qualitative analysis of the transformations in the socio-economic sphere associated with the spread of the COVID-19 pandemic in the world. On the basis of factual and statistical information, the features of the current situation are identified, as well as the processes and trends of development that can lead to fundamental, long-term changes in the socioeconomic life of society.Conclusions and Relevance: a qualitative analysis of the impact of COVID-19 on the social and economic spheres of society shows that the impact of the coronavirus pandemic has crossed the boundaries of the exclusive medical and biological perception of this phenomenon and is increasingly acquiring an economic and socio-humanitarian dimension.
Aplikasi Amelioran Tanah dan MycoSilvi pada Falcataria sp. dan Ochroma bicolor Rowlee. untuk Reklamasi Lahan Pascatambang Pasir Silika
Authors: Munawaroh Khoryfatul , Budi Sri Wilarso , Pamoengkas Prijanto 
Published: April 2021

Open pit mining of silica sand causes some soil degradations and environmental impacts, such as lowering soil pH, lowering soil fertility, soil compaction, and toxicity of micronutrients such as Al, Fe, and Zn. The aim of this study was to analyze the soil properties of land post mining of silica sand and to analyze the growth response of Falcataria sp. and Ochroma bicolor by combination of soil ameliorant and MycoSilvi. The experimental design was split plot design of two treatment factors, MycoSilvi and soil ameliorant. The main plot is MycoSilvi that consist of two levels (MycoSilvi and without MycoSilvi). The subplot is soil ameliorant that consisted of six levels (compost 0 g, lime 0 g; compost 0 g, lime 1.56 g; compost 0 g, lime 3.12; compost 9 g, lime 0 g; compost 9 g, lime 1.56 g; compost 9 g, lime 3.12 g). The results showed that the soil ameliorant (lime 3.12 g and compost 9 g) and MycoSilvi was the best treatment to increase height, diameter, biomass, and mycorrhizal colonization of Falcataria sp. and O. bicolor.

Keywords: MycoSilvi, reclamation, soil ameliorant
Model Simulasi PertumbuhanTanaman Jagung Manis Hibrida pada Jarak Tanam yang Berbeda
Authors: Ferdiansyah Ervan , Handoko Handoko , Impron Impron 
Published: April 2021

A sweet corn model was developed to simulate the growth and development of hybrid-sweet corn under different crop denssities. This research is comparing the data of the simulation model and the actual observation data in the field, which is then presented in graphical form. This model was conducted on six treatment combinations between three types of spacing and two varieties. The simulation model requires meteorological data (average temperature, humidity, precipitation, and radiation), soil water data, and crop chracteristics. There are five of the six plant combinations which graph show that the model is able to simulate the total maize corn biomass every week. The model was able to estimate 93% of the actual biomass and described the growth and development of hybrid-sweet corn as well.

Keywords: estimating biomass, models and simulations, plant growth
Pertumbuhan Bibit Cendana (Santalum album L.) dengan Inang Primer pada Intensitas Radiasi Berbeda
Authors: FanggidaE Yudi Riadi , Impron Impron , June Tania 
Published: April 2021

The primary host of sandalwood seeds (Santalum album L.) which is widely used in the nursery process is Alternanthera sp. However, the local name given to this primary host is same as that given to Portulaca sp. The same local name for these two-different species may cause mistakes in the use of the primary host during the cultivating process of sandalwood. Meanwhile, the ability of the Portulaca sp. as the primary host is unknown. Information about the right radiation intensity of the sandalwood seedling is still limited. The study aims to analyze the growth of sandalwood seedlings grown with primary host of Alternanthera sp. and Portulaca sp. at different radiation intensities. The completely randomized design with two treatments factor were used, namely differences in shade levels (without shade, 25, 50, and 75%) and differences in the types of primary hosts. The result showed that the primary hosts of Alternanthera sp. have the best growth for sandalwood seeds compared to sandalwood seedlings planted with Portulaca sp. The shading must be adjusted to the type of primary host. Sandalwood seeds grown with Alternanthera sp. as primary hosts grow best at 50% and 75% paranet shade conditions, in radiation range of 9.86–12.17 MJ/m2/day. Sandalwood seeds planted with Portulaca sp. as a primary host grow best in 25% paranet shade, that is at average radiation of 13.62 MJ/m2/day. The use of Alternanthera sp. and shade provision (50–75%) is highly recommended in sandalwood seedlings.

Keywords: haustoria, hemiparasite, primary host plant, sandalwood, symbiosis
Новые результаты использования световой ловушки при сборе жесткокрылых (Insecta: Coleoptera) в условиях городской среды (на примере г. Саратова)
Authors: Сажнев А.С. , Аникин В.В. 
Published: April 2021

В статье приведены результаты применения световой ловушки при изучении фауны жесткокрылых в условиях г. Саратова. В 2019 г. собраны представители 52 видов жесткокрылых 22 семейств, принадлежащие к различным экологическим группировкам. Отмечена относительно высокая доля адвентивных видов в получаемых сборах (2018 г. – 30.7%, 2019 г. – 17.3%). За два года (2018–2019) было зарегистрировано 14 чужеродных и криптогенных для европейской части России видов жесткокрылых, что составляет 24.5% от адвентивной фауны Саратовской области. Рекомендуется использовать привлечение на свет, как вспомогательный доступный и малозатратный способ изучения адвентивной фауны в условиях городской среды.

БлагодарностиЧасть работы А.С. Сажнева проведена в рамках выполнения государственного задания Министерства науки и высшего образования РФ (АААА-А18-118012690105-0).
Biological characteristics of influenza virus subtype H6N8 isolated from wild birds in the south of Western Siberia
Authors: Li X. , Dubovitskiy N. A. , Derko A. A. , Glushchenko A. V. , Sobolev I. A. , Druzyaka А. V. , Medzhidova М. М. , Musinova E. М. , Sharshov К. A. , Shestopalov A. М. 
Published: April 2021

Aim. The aim is to explore the molecular and biological characteristics of influenza virus subtype H6N8.Material and Methods. Regular collecting of biological samples from wild birds was carried out in 2016 in the south of Western Siberia. Isolation of avian influenza virus strains from birds’ cloacal swabs was performed using three passages in embryonated chicken eggs. Hemagglutination assay was used to detect viruses in the allantoic fluid. Type and subtype of influenza viruses were identified using reverse transcription PCR (RT‐PCR). Results. This is the first time the avian influenza virus H6N8 subtype has been isolated in Russia. Phylogenetic analysis revealed that hemagglutinin (HA) and neuraminidase (NA) segments of A/gadwall/Chany/97/2016(H6N8) strain genome belonged to the Eurasian lineages of avian influenza viruses. Phylogenetic analysis showed that the HA sequence of the strain was closely related to the strain isolated from a duck in Bangladesh in 2015 (A/duck/Bangladesh/25767/2015(H6N1).Conclusion. Avian influenza viruses subtype H6N8 have the ability to circulate among wild waterfowl and poultry, increasing the chance of reassortment and transmission of H6 virus strains among birds. For this reason, it is of crucial importance to strengthen surveillance for avian influenza H6 subtype among wild birds in the south of Western Siberia.
The participation of cyanobacteria in reducing the concentration of fusariotoxins and heavy metal ions in aqueous solutions (model experiments)
Authors: Domracheva L. I. , Skugoreva S. G. , Fokina A. I. , Zagoskin М. A. , Аshikhmina Т. Ya. 
Published: April 2021

Aim. The goal was to establish the effect of soil cyanobacteria (CB) Fischerella muscicola, Nostoc paludosum and Nostoc linckia on change in the concentration of heavy metal ions (HM) and fusariotoxins in aqueous media.Material and Methods. In order to plot the kinetics of sorption by dry biomass of CB Fischerella muscicola and Nostoc paludosum of copper(II), lead(II) and cadmium ions from solutions with a concentration of 10‐4mol/L, the method of potentiometry with ion‐selective electrodes was used. The concentration of fusariotoxins in the filtrate of the contact medium of Fischerella muscicola CB and Nostoc linckia with F. culmorumwas determined by HPLC.Results. The kinetics of sorption of TM ions by dry biomass of the CB isbest described by a modified second‐order model. According to the model, the sorption process limits the ion exchange reaction. In the presence of CB Fischerella muscicola and Nostoc linckia with a titer of 1.8∙106 cells/mL (1:100 dilution), a decrease in toxin and lycomarasmin in T‐2 medium occurs. However, this increases the concentration of fusaric acid and deoxynivalenol. In the variant where the titer of CB is equal to 1.8∙107cells/mL, the concentration of lycomarasmin is significantly reduced, while there is no change in the concentration of other fusariotoxins.Conclusion. Dry biomass of CB, having a high bisorption potential, can act as a good biosorbent with respect to copper(II), lead(II) and cadmium ions. A decrease in the concentration of fusariotoxins indicates the possibility of isolating active CB substances that can inhibit the biosynthesis of certain toxins of micromycetes of the genus Fusarium, reducing both the phytotoxicity of plant growth media and increasing the safety of crop production.