bluuebunny/crossref_metadata_2025_split huggingface dataset:
Képzési háttér és gyermekvállalási tervek
Authors: Veroszta Zsuzsanna , Györgyi Zoltán 
Published: October 2021

Összefoglaló. A tanulmány a népesedési folyamatok és az oktatási
rendszer kölcsönhatásának értelmezési keretében mozog. Ezen belül a szülői
végzettség egy lehetséges demográfiai következményével, a második gyermek
vállalásának tervezésére gyakorolt hatásával foglalkozik. Az elemzés a KSH NKI
Kohorsz ’18 Magyar Születési Kohorszvizsgálat várandósok körében gyűjtött
adatain alapul. Az eredmények alapján az anyák második gyermek vállalására
vonatkozó terveiben mindkét szülő végzettségének önálló hatása mutatható ki. A
szülői iskolázottság szintje és a második gyermek tervezése között pozitív a
kapcsolat. Legerősebb a felsőfokú végzettség hatása, mely mindkét szülő esetében
növeli a második gyermek tervezésének esélyét. A szakképzettség alacsony szinten
csökkenti, ugyanakkor a magasabb, középfok feletti szinteken növeli a
gyermekvállalási kedvet. Az anyai tervekre az apa legmagasabb iskolai
végzettsége is kimutatható hatással bír. Az eredmények oktatáspolitikai
szempontú értelmezésében kiemelhető a magasabb végzettségi szintek
gyermekvállalásra gyakorolt pozitív hatása, valamint a szakmunkásképzés felé
irányítás potenciálisan kedvezőtlen demográfiai következményeinek
azonosítása.
Summary. The interpretive framework of the study is the interaction
between demographic trends and the education system. Within this, it addresses a
possible demographic consequence of parental education, i.e., its impact on the
planning of having a second child. The analysis is based on the data of Cohort
’18 Growing Up In Hungary, collected among pregnant women by the Hungarian
Demographic Research Institute in 2018 as a part of a Hungarian Birth Cohort
Study. According to the results, the plans of the expecting mothers to have a
second child significantly affected by the educational attainment. As regards
directions, there is a linear positive relationship between the level of
education and the odds of planning a second child. Higher educational background
of both parents shows the strongest effect on the plans. Elementary vocational
training works against planning chances, but upper vocational background
increases the desire to have a second child. Educational attainment of the
partner also has a significant effect on maternal childbearing plans. From the
point of view of educational policy, the positive effect of higher education
degree on having children can be highlighted. Potentially unfavorable
demographic consequences of the direction towards vocational training can be
also highlighted by the results.
Biophilic design as a new approach in urban sustainability
Authors: Radha Chro Hama 
Published: October 2021

Abstract
Despite the clear benefits of maintaining a human relationship with nature, people increasingly live in urban settings. As a result of urbanization, numerous urban communities are confronting social and natural problems, which have genuinely compromised residents’ wellbeing and health. Thus, holistic planning and designing are needed to tackle these problems, integrating nature-based thinking into urban environmental development. The aim of this paper is to explore components of a sustainable city and biophilic design patterns and analyze the relationship between them. Finally, the conceptual model of a sustainable city has been proposed based on biophilic design approaches.
Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis
Authors: Müller-Deile Janina , Sopel Nina , Ohs Alexandra , Rose Victoria , Gröner Marwin , Wrede Christoph , Hegermann Jan , Daniel Christoph , Amann Kerstin , Zahner Gunther , Schiffer Mario 
Published: October 2021

Significance Statement
MicroRNA-192-5p (miR-192-5p) is upregulated in the glomeruli and urine of patients with idiopathic membranous glomerulonephritis (iMGN). It derives from glomerular endothelial cells, is packed into exosomes, and decreases podocyte nephronectin (NPNT) in the glomerular basement membrane (GBM) by paracrine signaling. Patients with iMGN have reduced glomerular NPNT expression. Whole-body knockdown of npnt in zebrafish and podocyte-specific knockout of Npnt in mice damage the GBM, increasing lucidity of the lamina rara interna, which admits high molecular weight proteins. Reduced NPNT leading to GBM leakiness might be an important part of iMGN pathophysiology, initiating podocyte antigen presentation, and admitting autoantibodies into the subepithelial space. NPNT might be a prognostic parameter and noninvasive marker for iMGN. Monitoring and targeting this miR could be a promising diagnostic and therapeutic approach for iMGN.

Background
Autoantibodies binding to podocyte antigens cause idiopathic membranous glomerulonephritis (iMGN). However, it remains elusive how autoantibodies reach the subepithelial space because the glomerular filtration barrier (GFB) is size selective and almost impermeable for antibodies.

Methods
Kidney biopsies from patients with iMGN, cell culture, zebrafish, and mouse models were used to investigate the role of nephronectin (NPNT) regulating microRNAs (miRs) for the GFB.

Results
Glomerular endothelial cell (GEC)-derived miR-192-5p and podocyte-derived miR-378a-3p are upregulated in urine and glomeruli of patients with iMGN, whereas glomerular NPNT is reduced. Overexpression of miR-192-5p and morpholino-mediated npnt knockdown induced edema, proteinuria, and podocyte effacement similar to podocyte-derived miR-378a-3p in zebrafish. Structural changes of the glomerular basement membrane (GBM) with increased lucidity, splitting, and lamellation, especially of the lamina rara interna, similar to ultrastructural findings seen in advanced stages of iMGN, were found. IgG-size nanoparticles accumulated in lucidity areas of the lamina rara interna and lamina densa of the GBM in npnt-knockdown zebrafish models. Loss of slit diaphragm proteins and severe structural impairment of the GBM were further confirmed in podocyte-specific Npnt knockout mice. GECs downregulate podocyte NPNT by transfer of miR-192-5p–containing exosomes in a paracrine manner.

Conclusions
Podocyte NPNT is important for proper glomerular filter function and GBM structure and is regulated by GEC-derived miR-192-5p and podocyte-derived miR-378a-3p. We hypothesize that loss of NPNT in the GBM is an important part of the initial pathophysiology of iMGN and enables autoantigenicity of podocyte antigens and subepithelial immune complex deposition in iMGN.
EARLY THEORIES AND PRACTICALITIES ON GOLD OCCURRENCE IN AUSTRALIA
Authors: McQUEEN KENNETH G. 
Published: October 2021

The discovery of gold in Australia forced many changes to theory on the occurrence and origin of gold deposits. Initial discoveries appeared to confirm existing ideas on the global distribution of gold-bearing terrains. Later discoveries and research would show that this confirmation was largely coincidental, but nevertheless helpful in early prospecting.
Prior to the first Australian gold rush, theoretical predictions of payable gold were made by Sir Roderick Murchison and Rev. W. B. Clarke based on knowledge of accidental gold finds and geological analogy with known areas of significant gold occurrence, particularly the Ural region in Russia. These predictions were overwhelmed when Edward Hargraves, realised he might be able to spark a gold rush that would prove the existence of payable gold. Hargraves travelled to the Bathurst region of New South Wales where numerous gold finds had already been made and with local guides, prospected Lewis Ponds Creek and the Macquarie River. He demonstrated the methods of alluvial mining, to John Lister and William and James Tom enabling them to find sufficient alluvial gold to initiate a gold rush. The crowd of attracted diggers demonstrated the existence of a payable goldfield. The unstoppable first rush resulted in the pragmatic introduction of government regulation and administration to allow alluvial gold mining. Other discoveries of payable goldfields quickly followed. As the local scientific expert on gold, W. B. Clarke was commissioned to conduct two extensive surveys of the goldfields between 1851 and 1853. Clarke also drew on his geological knowledge to provide practical advice to the thousands of prospecting gold diggers. Gold-bearing quartz reefs and lodes were discovered, but it was predicted that these could not be mined economically. Theory also predicted that the reef gold would not continue to depth.
Practical observations and mining experience from the numerous discoveries led to revision of the widely held dicta on gold occurrence. Alluvial gold was found in a range of settings, including the recent drainage and ancient and buried leads. A wider variety of rock types was recognised as favourable for gold. Different styles of reef gold were identified and found to be economically mineable to great depth. Evolving ideas on the origin of gold deposits were widely discussed, tested, and refined.
Of the many players involved in the early discovery of gold in Australia, Clarke, Hargraves and Murchison probably had the greatest overall influence in terms of theoretical predication and practical outcomes that initiated the Australian gold-mining industry.
The state of cognitive function in patients with stable coronary artery disease after coronary artery bypass grafting
Authors: Sokolova N. Yu. , Golukhova E. Z. , Savelyeva E. A. , Popov D. S. 
Published: October 2021

Aim To study the cognitive function (CF) state in patients with chronic ischemic heart disease (IHD) depending on the method of coronary bypass (CB), with extracorporeal circulation (EC) or on beating heart.Material and methods Postoperative cognitive dysfunction (POCD) is a frequent complication of CB, and its development may depend on the method of surgery, with EC or on beating heart. This single-center, prospective, nonrandomized study included 196 patients with chronic IHD aged 61.0±5.1 years. Patients were divided into two groups based on the CB method: an EC group (n=11) and a beating heart surgery group (n=85). Mean follow-up period was 26±2.1 mos. The state of CF was evaluated before and after CB (at the hospital stage, at 3, 6, 12, and 24 mos.).Results The mean duration of CF recovery was 3 mos. only in the group of CB without EC (p<0.05), whereas after CB with EC, CF parameters were similar to those during the hospital stage with somewhat reduced values. In 6 mos. after CB, CF normalized to baseline values in both groups (with and without EC). A possible CF decline in patients with chronic IHD after CB depended on the following factors: age older than 60 years (p<0.05), diabetes mellitus with glycated hemoglobin >7.5 % (p=0.001) and 6.5–7.5 % (p=0.03), smoking (p=0.04), atherosclerotic damage of the internal carotid artery (p<0.05), and a Charlson comorbidity index >5 (p=0.03). The CB surgery either with EC (p=0.04) or on beating heart (p=0.04) was associated with the development of CD.Conclusion The results of the study allow identifying patients with chronic IHD and POCD-predisposing factors to recommend them beathing heart CB surgery.
Predictive value of laboratory markers in the development of cardiac events in patients with stable coronary artery disease after elective endovascular revascularization
Authors: Svarovskaya A. V. , Arzhanik M. B. , Ogurkova O. N. , Kuzheleva E. A. , Baev A. E. , Garganeeva A. A. 
Published: October 2021

Aim To reveal a relationship between preprocedural laboratory data and adverse cardiac outcomes (CO) in patients with stable ischemic heart disease (IHD) following elective endovascular revascularization (ER).Material and methods This study included 225 patients with IHD admitted for treatment to the Research Institute of Cardiology of the Tomsk National Research Medical Center. The study included patients with documented IHD and hemodynamically significant coronary stenoses requiring elective ER. Patients were divided into groups based on the presence of complications: group 1, 98 patients with adverse CO and group 2, 127 patients without adverse CO. Besides evaluation of complaints, history, and objective status, general clinical and biochemical tests were performed for all patients. Concentration of glycated hemoglobin (НbА1с) was measured by immunoturbidimetry (DiaSys Diagnostic Systems). Serum concentrations of insulin, interleukin-6 (IL-6), endothelin 1 (ET-1), and homocysteine were measured by enzyme immunoassay. Blood lipid profile was determined by enzymatic colorimetry (DiaSys). Content of non-high-density lipoprotein (non-HDL) cholesterol (CS) was calculated as: CS – HDL CS. Insulin resistance (IR) was assessed by the HOMА-IR index. IR was diagnosed at the index of 2.77. Statistical analyses were performed with Statistica 10.0 and Medcalc 19.2.6 software.Results A one-way regression analysis identified predictors for adverse CO following ER. The most significant predictors were fibrinogen (odds ratio (OR), 1.430; 95 % confidence interval (CI), 1.027–1.990), HbA1c (OR 1.825; 95 % CI, 1.283–2.598), homocysteine (OR, 1.555; 95 % CI, 1.348–1.794), ET-1 (OR, 94.408; 95 % CI, 16.762–531.720), triglycerides (TG)/glucose ratio (OR 1.815; 95 % CI, 1.155–2.853). Based on selected factors, logistic regression models were constructed. However, not all models had a high prognostic power. Only concentrations of ET-1 and homocysteine showed a high prognostic capability in respect of the adverse outcome (88.3 and 85.7 %, respectively).Conclusion For patients with IHD, the prognostic capability of ET-1 and homocysteine with respect of the risk for adverse CO following ER was the highest compared to other markers. The results of the study are completely consistent with data of literature and can be successfully used in clinical practice for optimizing the medical care of patients after elective ER.
PERAN ETIKA KERJA ISLAM DAN KETERIKATAN KARYAWAN DALAM MENINGKATKAN ORGANIZATIONAL CITIZENSHIP BEHAVIOUR
Authors: Musoli Musoli , Yamini Era Agustina 
Published: October 2021

ABSTRACTThis study examines whether Islamic work ethics has a relationship with employee engagement and organizational citizenship behavior of employees in hospitals. The research design uses a quantitative approach through research instruments. Based on the purposive sampling technique, the unit of analysis in this study was the PKU Muhammadiyah Hospital employees in the Special Region of Yogyakarta who had worked for a minimum of 1 year. The total respondents in this study were 179 respondents from PKU Muhammadiyah Hospital employees in Yogyakarta Special Region. The results of this study indicate several empirical findings. First, Islamic work ethics has a positive influence on employee engagement. Second, Islamic work ethics has a positive effect on organizational citizenship behavior. Third, employee engagement has a positive impact on organizational citizenship behavior. ABSTAKPenelitian ini bertujuan untuk menguji apakah etika kerja Islam memiliki hubungan dengan keterikatan karyawan dan organizational citizenship behavior karyawan di Rumah Sakit. Desain penelitian menggunakan pendekatan kuantitatif melalui instrumen penelitian. Berdasarkan teknik purposive sampling, unit analisis dalam penelitian ini adalah karyawan Rumah Sakit PKU Muhammadiyah di Daerah Istimewa Yogyakarta yang sudah bekerja minimal masa kerja 1 tahun. Total responden dalam penelitian ini adalah 179 responden dari karyawan Rumah Sakit PKU Muhammadiyah di Daerah Istimewa Yogyakarta. Hasil penelitian ini menunjukkan beberapa temuan empiris. Pertama, etika kerja Islam memiliki pengaruh positif terhadap terhadap keterikatan karyawan. Kedua, etika kerja Islam memiliki pengaruh positif terhadap organizational citizenship behaviour. Ketiga, keterikatan karyawan mempunyai pengaruh positif terhadap organizational citizenship behaviour
A comparative study of biochemical parameters in mild and severe cases of COVID-19
Authors: Gulavani Gouri A. , Wali Smita V. , Panchbudhe Sanjyoti A. 
Published: October 2021

Background: COVID-19 has a range of clinical manifestations, including cough, fever, breathlessness, diarrhoea. Diagnosis of COVID-19 is commonly made through detection of SARS-CoV-2 RNA by PCR testing of a nasopharyngeal swab or other specimens. Evaluation and management of COVID-19 depend on the severity of the disease. This study was done to analyses the difference in the laboratory findings of the mild and severe cases in patients with COVID-19.Methods: In this study biochemical parameters of the patients with mild and those admitted in intensive care unit (ICU) of SKNMCGH, Pune were studied. Total 60 patients were included in this study. Standard deviation and mean were calculated from the values of biochemical parameters of COVID-19 patients in intensive care unit (ICU) and ward patients.Conclusions: We found levels of lactate dehydrogenase (LDH), C-reactive protein (CRP), Aspartate aminotransferase (AST), alanine aminotransferase (ALT), ferritin were significantly elevated in severely ill ICU admitted patients than mild patients. This may be useful for predicting progression towards a more severe form of COVID-19.
Role of early enteral feeding in mild and moderate acute pancreatitis
Authors: Roy Aswin George , T. V. Haridas 
Published: October 2021

Background: Timing of enteral feeding in acute pancreatitis was always a matter of controversy. Increasing evidence suggests that early enteral feeding reduces systemic and local complications of pancreatitis and thereby hospital stay. Hence the study has been undertaken to determine the feasibility, advantages and disadvantages of early enteral feeding in mild and moderate acute pancreatitis. Methods: Patients admitted with symptoms and signs suggestive of mild and moderate acute pancreatitis who were started on early enteral feeding (within 48 hours of admission) were included in study. Blood investigation results are used to classify patients accordingly to mild and moderate acute pancreatitis based on Ransons’s score. Patients were followed up and categorized based on development of complications, length of hospital stay.Results: Majority of the patients who were started on early enteral feeding showed significant decrease in complications and hospital stay. Study also suggested that age is a significant risk in development of complications. Gender is not significant in the development of complications.Conclusions: There is significant decrease in rate of systemic complication, local infective and non-infective complications, length of hospital stay among acute pancreatitis patients who were started on early enteral feeding (within 48 hours).
For better or worse: How more flexibility in working time arrangements and parental leave experiences affect fathers' working and childcare hours in Germany
Authors: Wanger Susanne , Zapf Ines 
Published: October 2021

Objective: In this study, we investigate the effect of flexible working time arrangements and parental leave experiences on the actual working and childcare hours of men.
Background: Many fathers want to spend more time with their children and actively participate in family life, but, after becoming a parent, most work even more hours than before. To better combine work and family, the possibility of flexible working time arrangements might play a crucial role for fathers, also to become more involved in childcare activities.
Method: We use longitudinal data of the German Socio-Economic Panel (SOEP) to examine how flexible working time arrangements, parental leave experiences, working hours, and childcare hours are related. Based on data between 2013 and 2019, panel regression models were estimated.
Results: The results show that a change from fixed to flexible working time regulations leads to an increase in working hours for men and fathers. The longer working hours of fathers go hand in hand with a reduction in the time spent on childcare activities when switching to flexible working time arrangements. However, experiences with parental leave in connection with flexible working hours show a change in the use of time.
Conclusion: Flexible working time regulations prove to be ambivalent for fathers: On the one hand, they offer fathers new leeway, on the other hand, due to traditional role models, they lead to longer working hours and thus less participation in childcare; but parental leave experiences make a difference, which indicates the importance of these regulations for fathers.
Trifocal Tibial Bone Transport Using a Magnetic Intramedullary Nail
Authors: Hwang James , Sems Stephen , Yuan Brandon 
Published: October 2021

Case:
The patient sustained a pathologic fracture through chronic osteomyelitis of the tibia. Treatment involved resection of bone and soft tissue, leaving a 15-cm diaphyseal tibial defect. We designed a construct to allow for trifocal bone transport using a magnetic intramedullary lengthening nail connected to cables. This technique uses cables secured to the proximal tibia, the nail, and the transport segments.

Conclusion:
This case details the successful use of trifocal cable-assisted bone transport through a magnetic lengthening intramedullary nail. This technique can successfully be used to reconstruct diaphyseal bone defects that are longer than the stroke length of the magnetic nail.
In Situ Reconstruction of a Painful Sternal Z-Deformity Nonunion in a Severely Osteoporotic and Kyphotic Patient
Authors: Mavrommatis Sophia , Thomas Claire N. , Schroder Lisa K. , Cole Peter A. 
Published: October 2021

Case:
An osteoporotic and kyphotic 72-year-old woman presented with sternal pain, severe chest instability, and shortness of breath secondary to a traumatic sternal nonunion resulting from an unhealed sternal fracture sustained in a motor vehicle accident several months earlier. One-year functional and radiographic outcomes are presented with complete resolution of symptoms.

Conclusion:
Consideration for treatment with multiplanar, contourable, locked plating, augmented by autogenous graft, is warranted in the setting of sternal deformity and nonunion, particularly in the setting of osteoporosis and other sagittal plane deformity.
Posterior Talar Body Fracture With Flexor Hallucis Longus Incarceration
Authors: McLaughlin William M. , Moran Jay , Brand Jordan , Kahan Joseph B. , Yoo Brad 
Published: October 2021

Case:
A 58-year-old man presented with entrapment of the flexor hallucis longus (FHL) tendon between fractured fragments of the talar body. The patient was successfully treated with atypical operative approaches to release the tendon and reduce the fracture. At the 1-year follow-up, the patient remained asymptomatic with the ability to extend and flex of all toes. This case illustrates a unique surgical approach for this presentation.

Conclusions:
With proper utilization of positioning and fluoroscopy, posterior talar body fractures with entrapment of the FHL can be stabilized and corrected with dual use of medial-sided approaches.
Retos de futuro en la gestión de los recursos humanos públicos en Brasil y España
Authors: Nebot Carmen Pineda 
Published: October 2021

El objetivo del trabajo es conocer, mediante el estudio comparativo de dos países: Brasil y España, si a pesar de las diferencias tanto de tamaño, territorial como humano, como de desarrollo son similares los retos de futuro a los que se enfrentan en la gestión de los recursos humanos públicos. Las políticas públicas actuales cada vez más complejas, interconectadas, volátiles y fragmentadas junto con las nuevas herramientas tecnológicas hacen cada vez más necesario un nuevo perfil de empleados públicos, empleados que deben ser innovadores, con orientación estratégica, flexibles, creativos y motivados. Para ello es preciso, y así lo están planteando muchos expertos, modificar tanto los sistemas de selección de nuevos talentos como de formación de los existentes. Es importante, por tanto, que se utilice una gestión estratégica de los recursos humanos, gestión que debe tener en cuenta las especiales características de lo público.