bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preserving Values
Authors: DE LEON JUSTIN 
Published: December 2021

Abstract
This article explores the prevenance of militarization within the important cultural and political space of the powwow. Finding popular explanations of military service (such as poverty, lack of opportunity, and desired upward social mobility) insufficient in explicating the visibility of militarization, this work illustrates how colonially suppressed values have been enacted through the creation of new symbols and forms of practice. Looking to the use of warrior staffs, the Lakota sacred numbers, and the Lakota Flag Song, the article focuses on warriorhood and illustrates how traditional cultural practices are preserved through cunning navigations and transformations of colonial landscapes, allowing for a creative expression of individual and communal sovereignty.
Generative Refusal: Creative Practice and Relational Indigenous Sovereignty
Authors: WRIGHTSON KELSEY R. 
Published: December 2021

Abstract
This article critiques narrow conceptions of sovereignty, while holding up Indigenous practices of sovereign place making and creative relational sovereign enactment. I come into this contestation by thinking through creative acts of sovereignty as a generative praxis. Informed by these practices offers a new way of thinking about sovereignty as practiced, generative and relational. Grounded practices of Indigenous peoples in Denendeh (Northwest Territories, Canada) and the authors own experience as a settler living and working in Denendeh, this article also offers a space to think through ‘refusability’ as relational response.
Can There Be Justice Here?
Authors: CHAO SOPHIE 
Published: December 2021

Abstract
This article examines the intersecting forms of social and environmental injustice shaping the lifeworld of Indigenous Marind communities and their more-than-human ecologies in the Indonesian-controlled province of West Papua. Over the last decade, large-scale deforestation and monocrop oil palm expansion have radically undermined Marinds’ intimate and ancestral kinships with sentient forest plants and animals, as well as the moral principles that undergird interspecies relations. These transformations are exacerbated by conservation practices that are undertaken in the name of corporate sustainability but that are problematically premised upon an assumed divide between humans and the environment. The exclusion of Marind from natures both exploited and preserved sits in turn within a long-standing and ongoing history of violence and discrimination perpetrated against West Papuans under Indonesian rule. Drawing from Marind philosophies, practices, and protocols of more-than-human relationality, I examine how Marind conceive and contest the possibility of justice now and in the future—for themselves, forest organisms, and oil palm—amidst multiple, overlapping, and intersecting injustices provoked by capitalism, conservation, and colonialism. I invite an expansion of the scope and subjects of justice beyond the human that remains nonetheless acutely attentive to the persistence of capital-colonial regimes systematically positioning Indigenous peoples as killable before the law.
Embedded Bordering
Authors: MCEVOY JOSHUA K. , MIDZAIN-GOBIN LIAM 
Published: December 2021

Abstract
Borders and bordering practices can be understood as both an act of sovereign authority and establishing the contemporary international system. The drawing of borders also simultaneously legitimizes the state’s sovereign authority, creating a political community ‘inside’ borders through which modern politics takes place. These processes are especially pertinent for settler states such as Canada, whose sovereign authority over its recognized territory is contingent on the erasure of Indigenous sovereignty. However, Indigenous nations reject Canadian claims of settler authority and legitimacy, instead continuing to uphold their own modes of governance and relationships to territory. This contestation of settler territoriality is practiced in various ways, with this article exploring how energy utility governance and infrastructure act as bordering practices—that is, as a productive means of manifesting and demonstrating territorial authority. Through the British Columbia Utilities Commission’s Indigenous Utilities Regulation Inquiry, we explore the contestation of territory through what we refer to as ‘embedded bordering’. In doing so, we identify a tension between ongoing settler moves to dispossession alongside decolonial potential in the border-making practices of energy governance and infrastructure.
Nano White Food and the Reproduction of Whiteness
Authors: LYONS KRISTEN , FREDERICKS BRONWYN , BRADFIELD ABRAHAM , MAYES CHRISTOPHER , KOERNER CATHERINE 
Published: December 2021

Abstract
Since colonisation began in Australia, it has transformed the ecological, social, cultural, and economic bases of the biggest estate on earth, with outcomes driving the disruption of Indigenous food sovereignty, foodways and food knowledges alongside the reproduction of Whiteness. This article critically examines the place of White food, including the case of nanotechnologies, in the expansion of the settler colonial frontier, and its impacts for Indigenous health and relationships with food. To do this, we consider a widely commercialised nano-food application: the addition of nano-scale titanium dioxide to make foods White. Nano White food provides a unique lens to examine White authority and control across settler colonial food systems. We consider some of the impacts arising from this global colonial power matrix—to which Whiteness is organising principle for domination—for Aboriginal and Torres Strait Islander health, justice, and rights. We argue that unsettling Whiteness is vital to redressing the violence wrought by settler colonial agri-food systems, and for re-centring living ecologies and interconnected systems across foodways.
A new extension of Odd Half-Cauchy Family of Distributions: properties and applications with regression modeling
Authors: Chakraburty Subrata , Alizadeh Morad , Handique Laba , Altun Emrah , Hamedani G. G. 
Published: December 2021

Abstract
The paper proposes a new family of continuous distributions called the extended odd half Cauchy-G. It is based on the T
–
X construction of Alzaatreh et al. (2013) by considering half Cauchy distribution for T and the exponentiated G(x;ξ) as the distribution of X. Several particular cases are outlined and a number of important statistical characteristics of this family are investigated. Parameter estimation via several methods, including maximum likelihood, is discussed and followed up with simulation experiments aiming to asses their performances. Real life applications of modeling two data sets are presented to demonstrate the advantage of the proposed family of distributions over selected existing ones. Finally, a new regression model is proposed and its application in modeling data in the presence of covariates is presented.
A study on exponentiated Gompertz distribution under Bayesian discipline using informative priors
Authors: Aslam Muhammad , Afzaal Mehreen , Ishaq Bhatti M. 
Published: December 2021

Abstract
The exponentiated Gompertz (EGZ) distribution has been recently used in almost all areas of human endeavours, starting from modelling lifetime data to cancer treatment. Various applications and properties of the EGZ distribution are provided by Anis and De (2020). This paper explores the important properties of the EGZ distribution under Bayesian discipline using two informative priors: the Gamma Prior (GP) and the Inverse Levy Prior (ILP). This is done in the framework of five selected loss functions. The findings show that the two best loss functions are the Weighted Balance Loss Function (WBLF) and the Quadratic Loss Function (QLF). The usefulness of the model is illustrated by the use of real-life data in relation to simulated data. The empirical results of the comparison are presented through a graphical illustration of the posterior distributions.
The problem of statistical assessment of the potential for the development of regional integration processes
Authors: Osaulenko Oleksandr , Bulatova Olena , Zakharova Olha , Reznikova Natallia 
Published: December 2021

Abstract
The present article illustrates the use of integrated indices to evaluate the potential for the development of regional integration processes. The study examines a new research and methodological approach, which involves the use of an integral index of the potential for the development of integration processes, proposed with regard to the intensity of the influence of internal and external factors on integrative relations development. The application of the above-mentioned integrated index in a comparative analysis of the potential for the development of integration processes allows a comprehensive and quantitative description of the current regional integration processes taking place in the modern economy under certain regional models.
Probabilistic interval estimation of design floods under non-stationary conditions by an integrated approach
Authors: Zhou Yanlai , Guo Shenglian , Xu Chong-Yu , Xiong Lihua , Chen Hua , Ngongondo Cosmo , Li Lu 
Published: December 2021

Abstract
Quantifying the uncertainty of non-stationary flood frequency analysis is very crucial and beneficial for planning and design of water engineering projects, which is fundamentally challenging especially in the presence of high climate variability and reservoir regulation. This study proposed an integrated approach that combined the Generalized Additive Model for Location, Scale and Shape parameters (GAMLSS) method, the Copula function and the Bayesian Uncertainty Processor (BUP) technique to make reliable probabilistic interval estimations of design floods. The reliability and applicability of the proposed approach were assessed by flood datasets collected from two hydrological monitoring stations located in the Hanjiang River of China. The precipitation and the reservoir index were selected as the explanatory variables for modeling the time-varying parameters of marginal and joint distributions using long-term (1954–2018) observed datasets. First, the GAMLSS method was employed to model and fit the time-varying characteristics of parameters in marginal and joint distributions. Second, the Copula function was employed to execute the point estimations of non-stationary design floods. Finally, the BUP technique was employed to perform the interval estimations of design floods based on the point estimations obtained from the Copula function. The results demonstrated that the proposed approach can provide reliable probabilistic interval estimations of design floods meanwhile reducing the uncertainty of non-stationary flood frequency analysis. Consequently, the integrated approach is a promising way to offer an indication on how design values can be estimated in a high-dimensional problem.
Toward sustainable water resources management: critical assessment on the implementation of integrated water resources management and water–energy–food nexus in Afghanistan
Authors: Shams Ajmal Khan , Muhammad Nur Shazwani 
Published: December 2021

Abstract
Afghanistan has abundant water resources; however, the current state of affairs is dismal because of the lack of integrated water resources management (IWRM) practices and prolonged war and conflict in the country. Therefore, there is a need for a systematic approach to water management, which can be materialized by integrating IWRM and the water–energy–food (WEF) nexus approach to maintain a critical balance of available water resources and their various uses at the national level. This study provides a comprehensive assessment of Afghanistan's water resource management, including the current state, challenges, opportunities, and way forward. The identified challenges are categorized as social and environmental issues, engineering and technical and regulatory, policy and government role. These challenges are inter-connected and a novel framework toward the implementation of IWRM and the WEF nexus in Afghanistan is proposed. This framework can be used by the relevant stakeholders to prepare a roadmap for sustainable management of water resources. Such integrative approaches will enhance Afghanistan's water, food, and energy security and significantly contribute to its economic development. Moving forward, the Afghanistan government must play a crucial role with regards to the efficient management of the country's water resources in an integrated manner as suggested in this paper.
Monitoring the health status of water mains using a scorecard modelling approach
Authors: Huang Yuzhi , Rameezdeen Raufdeen , Chow Christopher W. K. , Gorjian Nima , Li Yangyue , Liu Zijun , Ju Peiqing 
Published: December 2021

Abstract
There has been considerable research into prediction of water mains failure, however, those models are very complex and fail to convey the message of the health status of an asset to the relevant stakeholders. The study developed a ‘pipe health scorecard’ based on historical failure data which could be used for operation, maintenance, refurbishment, or replacement decisions by a water utility. This scorecard model was developed by using 160,413 pipe-condition data sets from the South Australian Water Corporation over ten years. Measures such as the Kolmogorov–Smirnov (KS) statistic, Area Under the ROC Curve (AUC), and Population Stability Index (PSI) showed the model is strong enough to predict the health status of water mains. The study found the factors influencing water mains failure to be in the order of importance: length, material, age, location (road vs verge), diameter, and operating parameters. The development of a simple but reliable model for the assessment of the health status of water mains will have major benefits to the water utility with the ability to identify and potentially replace water pipes prior to failure. Additional benefits of flexible scheduling of maintenance and replacement programs would contribute to cost savings.
Groundwater recharge pathway according to the environmental isotope: the case of Changwu area, Yangtze River Delta Region of China
Authors: He Liang , Zhang Junru , Chen Suozhong , Hou Manqing , Chen Junyi 
Published: December 2021

Abstract
Groundwater recharge is an important factor affecting water circulation. As groundwater has slow seepage, directly observing the seepage velocity and recharge path of groundwater in the aquifer is difficult. Environmental isotope technology has become an important means to clarify the mechanism of groundwater movement and the mechanism by which groundwater recharges from the micro and macro perspectives. The Changwu area of Jiangsu Province was taken as an example to identify the recharge sources of groundwater and the recharge paths of groundwater and surface water by using the measured data of isotopes D, 18O, 34S, and T. The results indicated that the shallow aquifer and the I confined aquifer in the Changwu area are mainly recharged by precipitation and surface lake water. The II confined aquifer along the Yangtze River is recharged by modern precipitation. Moreover, the II confined aquifer in the Henglin area was recharged by the ancient Yangtze River before 4,000 years ago, and no recharge relationship exists now. the recharge condition of the II confined aquifer around the northwest of Gehu Lake is in the climate environment of 8,000 years ago and was caused by the surface depression lake water at that time. Additionally, the concealed limestone aquifer is primarily supplied by the II confined aquifer, while the concealed sandstone aquifer supplies the II confined aquifer. Hence, to find out the recharge conditions of groundwater aquifers based on the environmental isotope is conducive to scientific and reasonable evaluation of groundwater resources and to ensure the sustainable development and utilization of groundwater resources.
Association between Benton Visual Retention Test Scores and PET Imaging in Elderly Adults
Authors: Abe Misaki , Kimura Noriyuki , Sasaki Yuuki , Eguchi Atsuko , Matsubara Etsuro 
Published: December 2021

Background:
The Benton Visual Retention Test (BVRT) is a well-validated and reliable
test for assessing visual memory and visuospatial function. However, the association between the
BVRT score and imaging biomarker of Alzheimer’s disease (AD) remains unclear.

Objective:
This study examined whether the BVRT score is associated with brain amyloid burden
and cortical glucose metabolism in elderly adults without dementia.

Methods:
A total of 69 elderly adults without dementia, including 45 subjects with amnestic mild
cognitive impairment and 24 cognitively healthy adults, underwent the BVRT and 11C-Pittsburgh
compound B (PiB) and 18F-fluorodeoxyglucose (FDG) positron emission tomography. The correct
scores in the BVRT were used for analyses. A multiple linear regression analysis was conducted to
investigate the relationship between BVRT scores and PiB or FDG uptake. Moreover, a voxel-wise
linear regression analysis of the association between BVRT scores and PiB or FDG uptake was conducted
using Statistical Parametric Mapping.

Results:
After adjusting for age, sex, education, and ApoE4 status, the BVRT scores were inversely
correlated with the mean PiB uptake (β = −0.35, P = 0.003), whereas they were positively correlated
with FDG uptake (β = 0.266, P = 0.038). Moreover, the BVRT scores were inversely correlated
with amyloid burden in the right superior temporal and superior frontal gyri and the left parietal
lobe, whereas they were positively correlated with cortical glucose metabolism in the right posterior
cingulate and milled temporal gyri, left temporoparietal lobe, and right superior frontal gyrus.

Conclusion:
BVRT scores are correlated with brain amyloid burden and cortical glucose
metabolism, mainly in regions commonly affected in AD.
In Silico Studies of Piperidine Derivatives as Protein Kinase B Inhibitors
through 3D-QSAR, Molecular Docking and Molecular Dynamics Simulation
Authors: Liu Sisi , Li Yaxin , Wang Jin , Rui Xue , Tian Haobo , Li Chenshuo , Guo Chunyan 
Published: December 2021

Background:
Protein kinase B (Akt) is a serine/threonine-protein kinase that drives the diverse
physiological process. Akt is a promising therapeutic target, which involves cancer cell growth, survival,
proliferation and metabolism.

Objective:
The study aims to design highly active Akt inhibitors, and to elucidate the structural requirements
for their biological activity, we analyzed the key binding features and summarized the structural
determinants for their bioactivities.

Methods:
A series of piperidine derivatives have been investigated employing three-dimensional quantitative
structure-activity relationship (3D-QSAR), molecular docking and molecular dynamics simulation.

Results:
The statistics of the comparative molecular field analysis (CoMFA) model (Q2=0.631, R2=0.951)
and the comparative molecular similarity index analysis (CoMSIA) model (Q2=0.663, R2=0.966) indicated
that our 3D-QSAR model was accurate and reliable. Besides, the stability of receptor-ligand interactions
under physiological conditions was then evaluated by molecular dynamics simulation, in agreement
with the molecular docking results.

Conclusion:
Our study provided valuable insights for the discovery of potent Akt inhibitors.
Association Analysis Between Introns and mRNAs in Caenorhabditis elegans
Genes with Different Expression Levels
Authors: Cao Yanjuan , Zhang Qiang , Yan Zuwei , Zhao Xiaoqing 
Published: December 2021

Background:
Introns are ubiquitous in pre-mRNA but are often overlooked. They also play
an important role in the regulation of gene expression.

Objective and Method:
We mainly use the improved Smith-Waterman local alignment approach to
compare the optimal matching regions between introns and mRNA sequences in Caenorhabditis elegans
(C. elegans) genes with high and low expression.

Results:
We found that the relative matching frequency distributions of all genes lie exactly between
highly and lowly expressed genes, indicating that introns in highly and lowly expressed genes have different
biological functions. Highly expressed genes have higher matching strengths on mRNA sequences
than genes expressed at lower levels; the remarkably matched regions appear in UTR regions, particularly
in the 3'UTR. The optimal matching frequency distributions have obvious differences in functional
regions of the translation initiation and termination sites in highly and lowly expressed genes. The
mRNA sequences with CpG islands tend to have stronger relative matching frequency distributions, especially
in highly expressed genes. Additionally, the sequence characteristics of the optimal matched
segments are consistent with those of the miRNAs, and they are considered a type of functional RNA
segment.

Conclusion:
Introns in highly and lowly expressed genes contribute to the recognition translation initiation
sites and translation termination sites. Moreover, our results suggest that the potential matching relationships
between introns and mRNA sequences in highly and lowly expressed genes are significantly
different and indicate that the matching strength correlates with the ability of introns to enhance gene
expression.
Lactose and Casein Cause Changes on Biomarkers of Oxidative Damage and Dysbiosis in an Experimental Model of Multiple Sclerosis
Authors: Escribano Begoña M. , Muñoz-Jurado Ana , Luque Evelio , Conde Cristina , Feijóo Montse , LaTorre Manuel , Valdelvira Manuel E. , Buendía Paula , Giraldo Ana I. , Caballero-Villarraso Javier , Santamaría Abel , Agüera Eduardo , Túnez Isaac 
Published: December 2021

Background and Objectives:Experimental autoimmune encephalomyelitis (EAE) in rats closely reproduces multiple sclerosis (MS), a disease characterized by neuroinflammation and oxidative stress that also appears to extend to other organs and their compartments. The origin of MS is a matter for discussion, but it would seem that altering certain bacterial populations present in the gut may lead to a proinflammatory condition due to the bacterial lipopolysaccharides (LPS) in the so-called brain-gut axis. The casein and lactose in milk confer anti-inflammatory properties and immunomodulatory effects. The objectives of this study were to evaluate the effects of administration of casein and lactose on the oxidative damage and the clinical status caused by EAE and to verify whether both casein and lactose had any effect on the LPS and its transport protein -LBP-.Methods:Twenty male Dark Agouti rats were divided into control rats (control), EAE rats, and EAE rats, to which casein and lactose, EAE+casein, and EAE+lactose, respectively, were administered. Fifty-one days after casein and lactose administration, the rats were sacrificed, and different organs were studied (brain, spinal cord, blood, heart, liver, kidney, small, and large intestine). In the latter, products derived from oxidative stress were studied (lipid peroxides and carbonylated proteins) as well as the glutathione redox system, various inflammation factors (total nitrite, Nuclear Factor-kappa B p65, the Rat Tumour Necrosis Factor-α), and the LPS and LBP values.Results and Conclusion:Casein and lactose administration improved the clinical aspect of the disease at the same time as reducing inflammation and oxidative stress, exerting its action on the glutathione redox system, or increasing GPx levels.