bluuebunny/crossref_metadata_2025_split huggingface dataset:
LITERATUR REVIEW : PENERAPAN BATUK EFEKTIF DAN FISIOTERAPI DADA UNTUK MENGATASI KETIDAKEFEKTIFAN BERSIHAN JALAN NAFAS PADA KLIEN YANG MENGALAMI TUBERCULOSIS (TBC)
Authors: Wahyu Widodo, Siska Diyah Pusporatri  
Published: July 2021

Tuberculosis is a disease caused by mycobacterium tuberculosis that get into respiratory tract and the lungs so that there was rash in alveoli or inflammation, the alveolar walls then will shrink. The prevalence of tuberculosis based on doctor diagnosis by provience 2013-2018 indonesia occupies 0,4% of the population. Purpose : The Purpose of writing literature review is to conduct research on clients who have tuberculosis with ineffective airway clearance. Method : The method research used by analyzing articles and searching through google scholar by using the keywords “chest physiotherapy and effective cough”, “chest physiotherapy and effective cough”+”tuberculosis”, “management of effective cough and chest physiotherapy” + “tuberculosis”, “effect of effective cough and chest physiotherapy” + “tuberculosis”. Results : The result from 5 journals found that there was a change in breathing rhythm, are able t secrete, shorthnes of breath decreases after effective coughing and chest physiotherapy. Conclusions : The conclutions application of effective cough and chest physiotherapy in tuberculosis patients who experience ineffective airway clearance can reduce shortness breath and spuntum and it is recommended that client can do effective chough and chest physiotherapy independently
Features of preoperative planning for hip arthroplasty
Authors:   Main Military Clinical Hospital named after academician N.N. Burdenko Russian Defense Ministry, Moscow, Russia, Buryachenko B.P. , Vartholomew D.I. ,   Main Military Clinical Hospital named after academician N.N. Burdenko Russian Defense Ministry, Moscow, Russia
Published: July 2021

Relevance. Preoperative planning is an integral stage of hip replacement surgery, which reduces the number of complications and improves the accuracy of the installation of endoprosthesis components. Goal. Assess the accuracy of digital preoperative planning using mediCAD® v.6. Material and methods. The study included data from 276 patients with idiopathic coxarthrosis who were treated at the orthopedic department of the Center of Traumatology and Orthopedics of the Main Military Clinical Hospital named after N.N. Burdenko in the period from 2018 to 2020.The patients had X-rays of the pelvis and hip joint in two projections. All patients underwent total hip arthroplasty with cementless endoprostheses. Before surgery, all patients underwent preoperative planning using the mediCAD® v.6 software. After the operation, a control X-ray was performed, followed by an assessment of the obtained images in the same software. The planning accuracy was evaluated by comparing the parameters that were calculated in the program before the operation with the parameters of the installed implants. The results. The conducted study demonstrated the high accuracy of digital preoperative planning. The coincidence of the planned sizes of the acetabular component of the endoprosthesis and a deviation within +/- one size was observed in 93% of patients, femoral — in 84% of patients. Conclusion. Preoperative planning is an integral stage of hip replacement surgery, which allows you to perform the necessary preparation for the intervention. Digital planning allows you to simplify and speed up the process of preparing for an operation and improve the quality of its execution.
SMART Reflections on Policy Coherence, Legal Developments in the Netherlands and the Case for EU Harmonisation
Authors: Sjåfjell Beate , Veldman Jeroen 
Published: July 2021

SMART Reflections on Policy Coherence, Legal Developments in the Netherlands and the Case for EU Harmonisation Afterword to Erasmus Law Review Special Issue ‘Towards responsible business conduct in global value chains: policy coherence and relevant legal developments in the Netherlands’
The EU-funded project Sustainable Market Actors for Responsible Trade (SMART, 2016-2020), undertook an interdisciplinary and multilevel regulatory analysis of the barriers and possibilities for securing the contribution of private and public market actors to a sustainable future. Jurisdiction-specific contributions were an essential part of this broad regulatory analysis. This afterword reflects on the Dutch contributions included in this Special Issue, emphasising the urgency of securing policy coherence for sustainable business. The afterword highlights how individual initiatives by national legislators such as those of the Netherlands can be inspiring examples, while they also bring with them challenges including questions of scope and of legal certainty for businesses, specifically with regard to cross-border operations and activities. This leaves business with the difficult task of figuring out the various requirements and expectations and may lead to regulatory competition between EU member states. The afterword therefore concludes with a call for EU harmonisation, to give sustainability-oriented business a level playing field and provide legal certainty both for decision-makers in business and for those affected by the conduct of business across global value chains.
Alterations to arbuscular mycorrhizal fungal community composition is driven by warming at specific elevations
Authors: Yang Mei , Shi Zhaoyong , Mickan Bede S. , Zhang Mengge , Cao Libing 
Published: July 2021

Background
Global warming can alter plant productivity, and community composition which has consequences for soil-plant associated microorganisms. Arbuscular mycorrhizal fungi (AMF) are distributed widely and form symbiotic relationships with more than 80% of vascular plants and play a key role in nutrient cycling processes at the ecosystem scale.

Methods
A simulated warming experiment at multiple elevations (3,000, 3,500, 3,800, and 4,170 m) was conducted utilizing an in-situ open-top chamber (OTC) for exploring the effect of global warming on AMF community structure in the Qinghai-Tibet Plateau (QTP). This region has been identified as one of the most sensitive areas to climatic changes. Soil DNA was extracted and sequenced using next the Mi-Seq platform for diversity profiling.

Results
AMF richness was higher under the simulated warming chamber, however this only occurred in the elevation of 3,500 m. Warming did not alter other AMF alpha diversity indices (e.g. Shannon, Ace, and Simpson evenness index). Glomus and Acaulospora were the dominate AMF genera as assessed through their relative abundance and occurrence in control and warming treatments at the different elevations.

Conclusion
Warming changed significantly AMF community. The effects of warming on AMF community structure varied depend on elevations. Moreover, the occurrences of AMF in different genera were also presented the different responses to warming in four elevations.
Noise Pollution Analysis of Reserved Areas: Case Study of the Isparta Ayazmana Promenade Area
Authors: Sahin Candan Kus , Onay Busra , Sava Beyza 
Published: July 2021

The sustainable landscpe design is a strategic framework in city planning and urban recreational areas, important for the quality of life of an increasingly urbanized society. This study deals with a better understanding of visitors demand and noise properties of Ayazmana promenade area, located in Isparta city center, Turkiye. The approach in the study is an exploration one with a base in site observations, interviews and survey. However, the average noise levels of the area was measured between 43.1 to 58.1 dB(A) in Autumn and 50.2 to 62.0 dB(A) in Spring, respectively. The recreational characteristics of Ayazmana promenade area were further evaluated with survey methodology on total of 100 respondents. Moreover, majority of participants (79) reported to be visiting of that promenade area for cheating with friends, followed by 78 for traveling, 70 for walking, 65 for sitting in green open spaces and for picnic, 57 for listening music and 53 for sporting activities, respectively. It is noticeable that most of the respondents (92%) were described the Ayazmana promenade area is somewhat noisy. At the end of survey study, it was requested to assessed the Ayazmana promenade area with some suggestions by respondents.
Exposure to prolonged sedentary behavior on weekdays rather than weekends in white-collar workers in comparison with blue-collar workers
Authors: Fukushima Noritoshi , Kikuchi Hiroyuki , Amagasa Shiho , Machida Masaki , Kitabayashi Makiko , Hayashi Toshio , Odagiri Yuko , Takamiya Tomoko , Inoue Shigeru 
Published: July 2021

Abstract

Objectives
Objectively measured sedentary behavior (SB) on weekdays and weekends has been mainly assessed in white-collar workers, while data in blue-collar workers are sparse. Therefore, this study presented the difference in accelerometer-measured SB levels between weekdays and weekends, stratified by white- and blue-collar occupations.

Methods
This study was a sub-analysis of accelerometer data from 73 workers (31 blue-collar and 42 white-collar) at a Japanese manufacturing plant. SB was defined as ≤1.5 metabolic equivalents estimated using an accelerometer, and compared between weekdays and weekends by using mixed models adjusted for confounders. The proportion of workers who sat for ≤8 h/day on weekdays and weekends were compared using McNemar’s test.

Results
In white-collar workers, SB time on weekdays was significantly longer than that on weekends (598 vs 479 min/day, P &lt; .001). In blue-collar workers, there was no significant difference in SB time between weekdays and weekends (462 vs 485 min/day, P = .43). The proportion of workers who achieved the recommended SB levels (≤8 h) was only 4.8% for white-collar workers on weekdays and 54.8% on weekends (P = .04), while that of blue-collar workers was 45.2% and 58.1% respectively (P &gt; .99).

Conclusions
White-collar workers were exposed to significantly longer SB time on weekdays than on weekends, which was not the case in blue-collar workers. It may be rather challenging for white-collar workers to limit their SB time to the level recommended by the latest guidelines for better health, especially on weekdays.
Type of exercise may influence postural adaptations in chemotherapy‐induced peripheral neuropathy
Authors: Waibel Sarah , Wehrle Anja , Müller Jana , Bertz Hartmut , Maurer Christoph 
Published: July 2021

AbstractObjectiveTraditional posturography measurements characterize postural instability in patients with chemotherapy‐induced peripheral neuropathy (CIPN), while underlying postural control mechanisms remain unclear. Taking a model‐based approach can yield insights into these mechanisms. This study’s aim was to characterize the modifications in postural control of CIPN patients associated with exercise in relation to the postural behavior of healthy control participants (hCON) via an exploratory approach.MethodsThirty‐one CIPN patients were randomly assigned to two interventions (balance plus moderate endurance training vs. moderate endurance training only) and exercised twice per week over 12 weeks. Baseline data were compared to 36 matched hCONs. We recorded spontaneous sway and postural reactions to platform tilts using Optotrak and a Kistler force platform pre‐ and post‐intervention. Data interpretation relied on a model‐based parameter identification procedure.ResultsSpontaneous sway amplitudes were larger and postural reactions smaller, with a relative phase advance, in our pre‐intervention patients than the hCONs. Post‐intervention, spontaneous sway, and postural reactions were reduced and the sensory‐motor ratio larger in both groups, while the postural reaction timing differed between groups.InterpretationThe abnormally small postural reactions in CIPN patients before the intervention can be interpreted as the consequence of abnormally strong velocity control—a strategy modification that may serve as a prediction mechanism to compensate for the lack of timely and accurate proprioceptive signals. While both groups reduced postural sway and showed an adapted sensory‐motor ratio post‐intervention, the interventions seemed to trigger different velocity control strategies. This study emphasizes the need for taking a more differentiated perspective on intervention effects.Trial registrationGerman Clinical Trials Register (DRKS) number: DRKS00005419, prospectively registered on November 19, 2013.
Serum MMP3 Correlated With IL1β Messenger RNA Expressions of Peripheral Blood Mononuclear Cells in Patients With Relapsing Polychondritis With Respiratory Involvement
Authors: Shimizu Jun , Wakisaka Sueshige , Suzuki Tomoko , Suzuki Noboru 
Published: July 2021

ObjectiveRespiratory involvement was intimately associated with poorer prognosis in patients with relapsing polychondritis (RP). We previously reported that high serum matrix metalloproteinase‐3 (MMP3) was frequently observed in patients with RP with respiratory involvement. Elevated MMP3 secreted through local inflammation may be associated with the development of airway lesions.MethodsWe collected peripheral blood mononuclear cells (PBMCs) and sera from 30 patients with RP and 14 healthy individuals. Interleukin (IL) 1β, IL6, and tumor necrosis factor (TNF) α messenger RNA (mRNA) expressions were analyzed in freshly isolated and cultured PBMCs with phytohemagglutinin and phorbol myristate acetate stimulation by real‐time reverse transcription polymerase chain reaction and serum MMP3 by enzyme‐linked immunosorbent assay (ELISA).ResultsWe confirmed our previous finding that patients with respiratory involvements showed higher serum MMP3 compared with patients lacking respiratory involvement. IL1β mRNA expression was significantly higher in patients with RP than in healthy individuals after mitogenic stimulation. TNFα mRNA expression after stimulation was significantly lower in patients with RP compared with in healthy individuals. We performed correlation analyses between MMP3 and cytokine mRNA expressions in patients with RP. In patients with respiratory involvement, MMP3 correlated with IL1β and IL6 after stimulation. In patients without respiratory involvement, no positive correlations between MMP3 and cytokine mRNA expressions were observed regardless of culture condition. We did not find any positive correlations between MMP3 and TNFα mRNA expression in patients with RP.ConclusionIt is possible that IL1β mRNA expression associates by some means with airway inflammation via the secretion of MMP3 in patients with RP. Involvement of proinflammatory cytokines, including IL1β, was suggested for the pathophysiology of airway lesions in patients with RP.
Incomplete reproductive isolation and low genetic differentiation despite floral divergence across varying geographic scales inCastilleja
Authors: Wenzell Katherine E. , McDonnell Angela J. , Wickett Norman J. , Fant Jeremie B. , Skogen Krissa A. 
Published: July 2021

PremiseDivergence depends on the strength of selection and frequency of gene flow between taxa, while reproductive isolation relies on mating barriers and geographic distance. Less is known about how these processes interact at early stages of speciation. Here, we compared population‐level differentiation in floral phenotype and genetic sequence variation among recently divergedCastillejato explore patterns of diversification under different scenarios of reproductive isolation.MethodsUsing target enrichment enabled by the Angiosperms353 probe set, we assessed genetic distance among 50 populations of fourCastillejaspecies. We investigated whether patterns of genetic divergence are explained by floral trait variation or geographic distance in two focal groups: the widespreadC. sessilifloraand the more restrictedC. purpureaspecies complex.ResultsWe document thatC. sessilifloraand theC. purpureacomplex are characterized by high diversity in floral color across varying geographic scales. Despite phenotypic divergence, groups were not well supported in phylogenetic analyses, and little genetic differentiation was found across targeted Angiosperms353 loci. Nonetheless, a principal coordinate analysis of single nucleotide polymorphisms revealed differentiation withinC. sessilifloraacross floral morphs and geography and less differentiation among species of theC. purpureacomplex.ConclusionsPatterns of genetic distance inC. sessiliflorasuggest species cohesion maintained over long distances despite variation in floral traits. In theC. purpureacomplex, divergence in floral color across narrow geographic clines may be driven by recent selection on floral color. These contrasting patterns of floral and genetic differentiation reveal that divergence can arise via multiple eco‐evolutionary paths.
A higher‐level nuclear phylogenomic study of the carrot family (Apiaceae)
Authors: Clarkson James J. , Zuntini Alexandre R. , Maurin Olivier , Downie Stephen R. , Plunkett Gregory M. , Nicolas Antoine N. , Smith James F. , Feist Mary Ann E. , Gutierrez Karime , Malakasi Panagiota , Bailey Paul , Brewer Grace E. , Epitawalage Niroshini , Zmarzty Sue , Forest Félix , Baker William J. 
Published: July 2021

PremiseThe carrot family (Apiaceae) comprises 466 genera, which include many well‐known crops (e.g., aniseed, caraway, carrots, celery, coriander, cumin, dill, fennel, parsley, and parsnips). Higher‐level phylogenetic relationships among subfamilies, tribes, and other major clades of Apiaceae are not fully resolved. This study aims to address this important knowledge gap.MethodsTarget sequence capture with the universal Angiosperms353 probe set was used to examine phylogenetic relationships in 234 genera of Apiaceae, representing all four currently recognized subfamilies (Apioideae, Azorelloideae, Mackinlayoideae, and Saniculoideae). Recovered nuclear genes were analyzed using both multispecies coalescent and concatenation approaches.ResultsWe recovered hundreds of nuclear genes even from old and poor‐quality herbarium specimens. Of particular note, we placed with strong support three incertae sedis genera (Platysace, Klotzchia, and Hermas); all three occupy isolated positions, with Platysace resolved as sister to all remaining Apiaceae. We placed nine genera (Apodicarpum, Bonannia, Grafia, Haplosciadium, Microsciadium, Physotrichia, Ptychotis, Tricholaser, Xatardia) that have never previously been included in any molecular phylogenetic study.ConclusionsWe provide support for the maintenance of the four existing subfamilies of Apiaceae, while recognizing that Hermas, Klotzschia, and the Platysace clade may each need to be accommodated in additional subfamilies (pending improved sampling). The placement of the currently apioid genus Phlyctidocarpa can be accommodated by the expansion of subfamily Saniculoideae, although adequate morphological synapomorphies for this grouping are yet to be defined. This is the first phylogenetic study of the Apiaceae using high‐throughput sequencing methods and represents an unprecedented evolutionary framework for the group.
Maple syrup urine disease: Characteristics of diagnosis and treatment in 45 patients in Chile
Authors: Medina María Fernanda , Castro Gabriela , Falcon Felipe , Cabello Juan Francisco , Faundes Víctor , Ruffato Diana , Salazar María Florencia , Arias Carolina , Peñaloza Felipe , De La Parra Alicia , Cornejo Verónica 
Published: July 2021

AbstractMaple urine syrup disease (MSUD) is an autosomal recessive disorder characterized by deficient activity of the branched‐chain alpha ketoacid dehydrogenase (BCKAD) enzymatic complex due to biallelic variants in the alpha (BCKDHA) or beta (BCKDHB) subunits or the acyltransferase component (DBT). Treatment consists in leucine (LEU), isoleucine (ILE), and valine (VAL) (branched‐chain amino acids) dietary restriction and strict metabolic control. to determine the characteristics of the Chilean cohort with MSUD currently in follow‐up at Instituto de Nutrición y Tecnología de los Alimentos, during the 1990–2017 period Retrospective analytical study in 45 MSUD cases. Measured: biochemical parameters (LEU, ILE, and VAL), anthropometric evaluation, and neurocognitive development. In 18 cases undergoing genetic study were analyzed according to the gene and protein location, number of affected alleles, and type of posttranslational modification affected. Then, 45 patients with MSUD diagnosis were identified during the period: 37 were alive at the time of the study. Average diagnosis age was 71 ± 231 days. Average serum diagnosis LEU concentrations: 1.463 ± 854.1 μmol/L, VAL 550 ± 598 μmol/L and ILE 454 ± 458 μmol/L. BCKDHB variants explain 89% cases, while BCKDHA and DBT variants explain 5.5% of cases each. Variants p.Thr338Ile in BCKDHA, p.Pro240Thr and p.Ser342Asn in BCKDHB have not been previously reported in literature. Average serum follow‐up LEU concentrations were 252.7 ± 16.9 μmol/L in the <5 years group and 299 ± 123.2 μmol/L in ≥5 years. Most cases presented some degree of developmental delay. Early diagnosis and treatment is essential to improve the long‐term prognosis. Frequent blood LEU measurements are required to optimize metabolic control and to establish relationships between different aspects analyzed.
Optimizing Electrode/Electrolyte Interphases and Li‐Ion Flux/Solvation for Lithium‐Metal Batteries with Qua‐Functional Heptafluorobutyric Anhydride
Authors: Huang Junda , Liu Jiandong , He Jian , Wu Mingguang , Qi Shihan , Wang Huaping , Li Fang , Ma Jianmin 
Published: July 2021

AbstractThe safety and electrochemical performance of rechargeable lithium‐metal batteries (LMBs) are primarily influenced by the additives in the organic liquid electrolytes. However, multi‐functional additives are still rarely reported. Herein, we proposed heptafluorobutyric anhydride (HFA) as a qua‐functional additive to optimize the composition and structure of the solid electrolyte interphase (SEI) at the electrode/electrolyte interface. The reduction/oxidation decomposition of the fluorine‐rich HFA facilitate uniform inorganic‐rich SEI and compact cathode electrolyte interphase (CEI) formation, which enables stable lithium plating during charge and suppresses the dissolution of transition‐metal ions. Moreover, HFA optimizes the Li‐ion solvation for stable Li plating/stripping and serves as the surfactant to enhance the wettability of the separator by the electrolyte to increase Li‐ion flux. The symmetric Li∥Li cell with 1.0 wt % HFA electrolyte had an excellent cycling performance over 340 h at 1.0 mA cm−2 with a capacity of 0.5 mAh cm−2 while the Li∥NCM622 cell maintained high capacity retention after 250 cycles and outstanding rate performance even at 15 C.
Spontaneous Enhancement of Magnetic Resonance Signals Using a RASER
Authors: Korchak Sergey , Kaltschnee Lukas , Dervisoglu Riza , Andreas Loren , Griesinger Christian , Glöggler Stefan 
Published: July 2021

AbstractNuclear magnetic resonance is usually drastically limited by its intrinsically low sensitivity: Only a few spins contribute to the overall signal. To overcome this limitation, hyperpolarization methods were developed that increase signals several times beyond the normal/thermally polarized signals. The ideal case would be a universal approach that can signal enhance the complete sample of interest in solution to increase detection sensitivity. Here, we introduce a combination of para‐hydrogen enhanced magnetic resonance with the phenomenon of the RASER: Large signals of para‐hydrogen enhanced molecules interact with the magnetic resonance coil in a way that the signal is spontaneously converted into an in‐phase signal. These molecules directly interact with other compounds via dipolar couplings and enhance their signal. We demonstrate that this is not only possible for solvent molecules but also for an amino acid.