bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spontaneous migration of a falling bullet in the cerebellum reveals the importance of intraoperative skull X-ray
Authors: Hammed Ali , Mahfoud Moufid , Sulaiman Alaa 
Published: March 2021

Abstract
Cranial gunshot wounds (CGSWs) are the most lethal types of the cranial traumas and they are usually mortal. Falling bullets or gravitational bullets are the ones that move under the effect of the gravity force after the muzzle force diminished. CGSWs constitute a major clinical challenge for neurosurgeons dealing with trauma in both the military and civil experience. We report the case of a 21-year-old man with a falling bullet wound to the head. The decision of surgical treatment of a bullet injury is difficult if it is in close proximity to vital structures; removal of the bullet may cause significant neurological damage; however, migration can lead to a worsening of the neurological status of the patient. Before surgical removal of any intracranial bullet, as valuable information, it is recommended that a plain skull X-ray be obtained after final positioning of the head.
Urban waste no replacement for natural foods—Marabou storks in Botswana
Authors: Francis R J , Kingsford R T , Murray-Hudson M , Brandis K J 
Published: March 2021

Abstract
We compared diets of marabou storks Leptoptilos crumenifer foraging from urban landfills and natural areas in northern Botswana using stable isotope analyses and inductively coupled plasma mass spectrometry on moulted feathers. There were significant differences in the diet of marabous foraging from natural areas compared to urban waste sites, reflected by lower δ13C and less enriched δ15N concentrations in those feeding at landfills, suggesting a shift in trophic niche. Feathers from birds foraging at landfills also had significantly higher concentrations of chromium, lead, nickel, and zinc and lower levels of cadmium and potassium than feathers sampled from natural areas. We also analysed marabou regurgitant (42 kg, naturally expelled indigestible food resources) from the Kasane landfill site. More than half was plastic, with single regurgitants weighing up to 125 g. Urban waste stored in open air landfills is altering some marabou diets, affecting their natural trophic niche, resulting in the consumption (and regurgitation) of large amounts of plastic, and exposing marabou to potentially chronic levels of trace metals. Despite the marabou’s apparent resilience to this behavioural shift, it could have long-term effects on the population of the marabou stork, particularly considering Botswana has some of the few regular marabou breeding colonies in southern Africa.
Higher Rates of Processed Pseudogene Acquisition in Humans and Three Great Apes Revealed by Long-Read Assemblies
Authors: Feng Xiaowen , Li Heng 
Published: March 2021

Abstract
LINE-1-mediated retrotransposition of protein-coding mRNAs is an active process in modern humans for both germline and somatic genomes. Prior works that surveyed human data mostly relied on detecting discordant mappings of paired-end short reads, or exon junctions contained in short reads. Moreover, there have been few genome-wide comparisons between gene retrocopies in great apes and humans. In this study, we introduced a more sensitive and accurate method to identify processed pseudogenes. Our method utilizes long-read assemblies, and more importantly, is able to provide full-length retrocopy sequences as well as flanking regions which are missed by short-read based methods. From 22 human individuals, we pinpointed 40 processed pseudogenes that are not present in the human reference genome GRCh38 and identified 17 pseudogenes that are in GRCh38 but absent from some input individuals. This represents a significantly higher discovery rate than previous reports (39 pseudogenes not in the reference genome out of 939 individuals). We also provided an overview of lineage-specific retrocopies in chimpanzee, gorilla, and orangutan genomes.
Surgical Relevance of the Suprameatal Tubercle During Superior Petrosal Vein-Sparing Trigeminal Nerve Microvascular Decompression
Authors: Rennert Robert C , Brandel Michael G , Stephens Marcus L , Rodriguez Analiz , Morris Thomas W , Day J D 
Published: March 2021

Abstract

BACKGROUND
An enlarged suprameatal tubercle (SMT) can obscure visualization of the trigeminal nerve and require removal during microvascular decompression (MVD) surgery, especially when the superior petrosal vein (SPV) complex is preserved.

OBJECTIVE
To define the incidence and important variables affecting the need for SMT removal with an SPV-sparing trigeminal nerve MVD.

METHODS
Retrospective single-institution review identified patients who underwent a first-time, SPV-sparing MVD for trigeminal neuralgia (TGN) over a 26-mo period. SMT length (SMT-L), SMT width (SMT-W), and peri-trigeminal cerebellopontine cisternal thickness (CT) were measured from axial high-resolution magnetic resonance images. Need for SMT removal and use of endoscopic assistance was recorded. Data were analyzed using unpaired t-tests, and receiver operating characteristic (ROC)/area under the curve testing.

RESULTS
A total of 43 MVD surgeries for TGN on 42 patients (mean age 52.7 ± 14.4 yr) were analyzed. Mean SMT-L, SMT-W, and CT were 9.8 ± 1.6, 2.0 ± 0.8, and 4.2 ± 1.5 mm, respectively. SMT removal via drilling was required in 4/43 cases (9.3%). Endoscopic assistance was used in 3 cases (2 SMT removed and 1 SMT preserved). SMT-W was the biggest predictor of the need for SMT removal on ROC analysis (area under the curve 0.97, 0.92-1.0 95% CI). The combined thresholds of SMT-W ≥ 3.2 mm and CT ≤ 3.5 mm demonstrated 100% sensitive and 100% specificity for the need to remove the SMT on optimal cutoff analysis.

CONCLUSION
SMT drilling is necessary in nearly 10% of SPV-sparing MVDs for TGN. The combination of SMT width and cerebellopontine cistern thickness is predictive of the need for SMT removal.
Education and management practices
Authors: Valero Anna 
Published: March 2021

Abstract:
The empirical management literature has found that the education of both managers and the workforce more generally appears to be an important driver of better management practices. This article sets out how such relationships might be conceptualized, and suggests that in a complementarities framework, modern management practices can be thought of as a type of skill-biased technology. It then summarizes the literature that has explored the relationships between human capital and surveyed management practices in manufacturing firms and other sectors, highlighting the handful of papers that have found a positive correlation between management practices and measures of local skills supply. It concludes with a discussion of the policy implications that stem from what we know so far, together with avenues for future research that could shed more light on the causal mechanisms at play.
Experience With Autologous Nasal Septum Cartilage Combined With Conchal Cartilage in Nasal Tip Reconstruction
Authors: Shi Yanyan , Tan Xiaoyan , Sun Haiyang , Char Sydney 
Published: March 2021

Objective
There has been an increase in use of autologous costal cartilage for nasal tip shaping material. However, there are deficiencies in using this plastic material, such as a hard nasal tip, poor nasal tip elasticity and mobility postoperatively, and some nasal tip skin thinning that allows the shape of the cartilage grafts to be felt on the surface of the nasal tip skin. To address these problems, we have combined autologous nasal septum cartilage and conchal cartilage as nasal tip graft materials, which achieve a natural shape and realistic touch postoperatively.

Methods
From January 2017 to September 2019, a total of 47 patients with nasal septal cartilage combined with conchal cartilage transplantation for nasal tip plasty were screened for a retrospective study. They were followed up and evaluated for 6 to 25 months postoperatively. The operation was performed through an incision in the nose. During the operation, a piece of septal cartilage was cut to make a columella strut. Using one side of the cavitas conchae and cymba conchae cartilage as the graft material, 2 long strips of cartilage were excised for the septum extension graft, and a piece of cap cartilage was transplanted to the top of the nasal tip cartilage scaffold.

Results
The time between the operation and follow-up was greater than 6 months, with the range of follow-up and evaluation being from 6 to 25 months. Forty-six patients were satisfied with the shape of the nose. One patient complained that the nasal tip was round and large after 1 month postoperatively, but after 6 months, he was satisfied with the shape of the nasal tip after daily use of a nasal clip. In one male case, the implant was removed more than 7 months postoperatively because of hematoma and infection secondary to nasal trauma. There were 2 cases of nasal tip numbness, both of which recovered spontaneously after 12 months. After the operation, the shape of the nasal tip was round, no cartilage contour was seen on the surface, no collapse of upper nasal tip, no obvious deviation of the nasal dorsum and columella, and no deformation and displacement of the nasal tip cartilage scaffold. At the 6-month follow-up visit, each patient palpated the nasal tip for evaluation. Most patients felt their nose felt realistic and that they had good nasal tip motion. Only 1 patient felt that the nasal tip and the nasal dorsum were moving together when the tip of the nose was being pushed.

Conclusions
Nasal septum cartilage and conchal cartilage can be combined as a graft material for reconstruction of the nasal tip. This technique uses different characteristics of each of the 2 cartilages to achieve a more realistic and esthetic outcome.
Implementation and Evaluation of Quality Improvement Training in Surgery
Authors: Pallari Elena , Khadjesari Zarnie , Aceituno David , Odhiambo Catherine Anyango , Warner Ross , Bastianpillai Christopher , Green James S. A. , Sevdalis Nick 
Published: March 2021

Objective:
The aim of this study was to review and appraise how quality improvement (QI) skills are taught to surgeons and surgical residents.

Background:
There is a global drive to deliver capacity in undertaking QI within surgical services. However, there are currently no specifications regarding optimal QI content or delivery.

Methods:
We reviewed QI educational intervention studies targeting surgeons or surgical trainees/residents published until 2017. Primary outcomes included teaching methods and training materials. Secondary outcomes were implementation frameworks and strategies used to deliver QI training successfully.

Results:
There were 20,590 hits across 10 databases, of which 11,563 were screened following de-duplication. Seventeen studies were included in the final synthesis. Variable QI techniques (eg, combined QI models, process mapping, and “lean” principles) and assessment methods were found. Delivery was more consistent, typically combining didactic teaching blended with QI project delivery. Implementation of QI training was poorly reported and appears supported by collaborative approaches (including building learning collaboratives, and coalitions). Study designs were typically pre-/post-training without controls. Studies generally lacked clarity on the underpinning framework (59%), setting description (59%), content (47%), and conclusions (47%), whereas 88% scored low on psychometrics reporting.

Conclusions:
The evidence suggests that surgical QI training can focus on any well-established QI technique, provided it is done through a combination of didactic teaching and practical application. True effectiveness and extent of impact of QI training remain unclear, due to methodological weaknesses and inconsistent reporting. Conduct of larger-scale educational QI studies across multiple institutions can advance the field.
Development of a direct NGM(1,1) prediction model based on interval grey numbers
Authors: Li Ye , Ding Yuanping , Jing Yaqian , Guo Sandang 
Published: March 2021

PurposeThe purpose of this paper is to construct an interval grey number NGM(1,1) direct prediction model (abbreviated as IGNGM(1,1)), which need not transform interval grey numbers sequences into real number sequences, and the Markov model is used to optimize residual sequences of IGNGM(1,1) model.Design/methodology/approachA definition equation of IGNGM(1,1) model is proposed in this paper, and its time response function is solved by recursive iteration method. Next, the optimal weight of development coefficients of two boundaries is obtained by genetic algorithm, which is designed by minimizing the average relative error based on time weighted. In addition to that, the Markov model is used to modify residual sequences.FindingsThe interval grey numbers’ sequences can be predicted directly by IGNGM(1,1) model and its residual sequences can be amended by Markov model. A case study shows that the proposed model has higher accuracy in prediction.Practical implicationsUncertainty and volatility information is widespread in practical applications, and the information can be characterized by interval grey numbers. In this paper, an interval grey numbers direct prediction model is proposed, which provides a method for predicting the uncertainty information in the real world.Originality/valueThe main contribution of this paper is to propose an IGNGM(1,1) model which can realize interval grey numbers prediction without transforming them into real number and solve the optimal weight of integral development coefficient by genetic algorithm so as to avoid the distortion of prediction results. Moreover, the Markov model is used to modify residual sequences to further improve the modeling accuracy.
Impact of periodic magnetic source on natural convection and entropy generation of ferrofluids in a baffled cavity
Authors: Zontul Harun , Hamzah Hudhaifa , Sahin Besir 
Published: March 2021

Purpose
This paper aims to exhibit a numerical study to analyze the influence of a periodic magnetic source on free convection flow and entropy generation of a ferrofluid in a baffled cavity. In this study, ferrofluid nanofluid was selected due to its ability to image magnetic domain structures within the cavity. The non-uniform magnetic source is considered as a sinusoidal distribution in the vertical direction.

Design/methodology/approach
The finite volume technique is used to evaluate the steady two-dimensional partial differential equations that govern the flow with its corresponding boundary conditions.

Findings
The obtained results indicate that a significant increase in the average Nusselt number can be achieved with the use of the periodic magnetic source instead of a uniform case. In addition, the effectiveness of the adiabatic baffle notably depends on its position and Rayleigh number. Regardless of the values of period and Hartmann numbers, the periodic magnetic source has a higher entropy generation and lower Bejan number than the uniform magnetic source.

Originality/value
The novelty of this research lies in applying a periodic magnetic source on the natural convection of ferrofluids in a baffled cavity.
The required specifications of a fourth-generation university to shape innovation district under anchor approach: a meta-synthesis analysis using text mining
Authors: Asgari Amir , Khorsandi Taskoh Ali , Ghiasi Nodooshan Saeed 
Published: March 2021

Purpose
This paper aims to introduce a conceptual model for the shaping of the innovation district under the anchor approach by extracting the specifications of the fourth-generation university.

Design/methodology/approach
This study selected 550 resources and reduced them to 190 to achieve the most appropriate resources. This study used a meta-synthesis analysis approach using a text-mining method due to the multidisciplinary and voluminous nature of contents.

Findings
The results first reveal the shaping process and the components of innovation districts, which are: innovational urban infrastructures, knowledge economy and competitiveness and academic development. Second, this study also shows the specifications of a fourth-generation university to shape innovation districts.

Practical implications
This study also informs the policymakers and researchers internationally about the implementation requirements of a fourth-generation university and the shaping mechanisms of an innovation district.

Originality/value
This paper is pioneer about two concepts, first, it shows the shaping process of an innovation district, providing a large-scale insight about the components and second, this illustrates for the first time the specifications of a fourth-generation University practically as an anchor institute to shape innovation district.
Servitisation through structural adaptation
Authors: Zighan Saad , Alkalha Ziad , Bamford David , Reid Iain , Al-Zu'bi Zu'bi M.F. 
Published: March 2021

PurposeThe purpose of this study is to investigate the structural changes needed for project-based organisations (PBOs) to synthesise their project operations and services following the servitisation strategy. It addresses the question of how PBOs should change their organisational structure fitting with service provision strategy.Design/methodology/approachThis study followed an exploratory research method using a single in-depth case with evidence collected from 51 project managers from five different industry sectors: construction, oil and gas, IT, logistics and health careFindingsCapitalising on organisational design theory, it has been found that successfully extending PBOs' outcomes into a system of both project output and extra services requires an adjustment of organisational structure that creates greater value for both companies and customers. This required adjustment has been divided into five main categories: (1) collaboration cross-project and customers; (2) flexible workflow, (3) decentralised decision-making, (4) wide span of control and (5) project governance. However, the findings indicate that success can only be ensured by particular mutually coordinated organisational designs with a suitable balance of products and servicesPractical implicationsThis study presents vital indicators to PBOs practitioners when deploying servitisation within their operational strategy by adjusting the organisation's design.Social implicationsServitisation could add both economic and social values for a diverse set of project stakeholders. However, the sustainability performance of servitisation in servitised project-based organisations is an outcome of reducing the discrepancy between project operation and service provision activities.Originality/valueThis study contributes to the body of knowledge and proposes a structural alteration process in PBOs to help align project operations and service provision activities. It explains how project-based organisations reconfigure their resources to provide services.
Rapid prototyping vaccine approach in mice against multi‐drug resistant Gram‐negative organisms from clinical isolates based on outer membrane vesicles
Authors: Pritsch Michael , Ben Khaled Najib , Liegl Gabriele , Schubert Soeren , Hoelscher Michael , Woischke Christine , Arens Nathalie , Thorn‐Seshold Julia , Kammermeier Stefan , Wieser Andreas 
Published: March 2021

AbstractHospital‐acquired infections due to multi‐drug resistant Gram‐negative organisms (MDRGNO) pose a major threat to global health. A vaccine preventing colonization and consecutive infection with MDRGNO could be particularly valuable, as therapeutic options become increasingly limited. Outer membrane vesicles (OMV) of Escherichia coli strain CFT073 as well as three MDRGNO strains that had caused severe infections in humans were administered intranasally to mice, with and without cholera toxin as an adjuvant. The humoral immune responses were comparatively matched with the sera of patients, who had suffered an infection caused by the respective bacterium. Additionally, systemic and local toxicity was evaluated. Intranasal vaccination with OMV could elicit solid humoral immune responses (total IgM and IgG), specific for the respective MDRGNO in mice; decoration of vital bacterial membranes with antibodies was comparable to patients who had survived systemic infection with the respective bacterial isolate. After intranasal vaccination of mice with OMV no signs of local or systemic toxicity were observed. Intranasal vaccination with OMV may open up a rapid vaccine approach to prevent colonization and/or infection with pathogenic MDRGNOs, especially in an outbreak setting within a hospital. It may also be an option for patients who have to undergo elective interventions in centers with a high risk of infection for certain common MDRGNO. Future studies need to include challenge experiments as well as phase I trials in humans.
The case for “investigate all”: Assessing the cost‐effectiveness of investigating no CODIS hit cases in a sexual assault kit initiative
Authors: Lovell Rachel E. , Singer Mendel , Flannery Daniel J. , McGuire Margaret J. 
Published: March 2021

AbstractAn increasing number of US jurisdictions have begun to submit their previously untested sexual assault kits (SAKs) for DNA testing. However, best practices for what should happen after testing are not well established. Should all cases be investigated regardless of the testing outcome or only those that returned a DNA hit? We examine an early‐adopter jurisdiction that has completed testing and investigating all 5165 previously never tested kits. We explore and compare the criminal justice outcomes and cost‐effectiveness of investigating: all cases, those with CODIS hits, and those without CODIS hits. Findings indicate the SAK initiative produced a cost savings to the community: $26.48 million ($5127 p/kit) after the inclusion of tangible and intangible costs of future sexual assaults averted through convictions, of which $9.99 million ($1934 p/kit) was from also investigating no CODIS hit cases. When considering only the costs to law enforcement, investigating all cases cost $12,000 p/additional conviction. Findings also illustrate the cost‐effectiveness of investigating no CODIS hits cases and support an “investigate all” approach. This study enhances our understanding of the economic value of what comes after testing kits and investigating cases and provides a framework for jurisdictions for prioritizing resources and maximizing outcomes from testing.