bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnostic value of cystatin C for the early diagnosis of diabetic nephropathy
Authors: Vasilkova V. N. , Pchelin I. Yu. , Naumenka E. P. , Borovets Ya. A. , Yarets Yu. I. , Korotaeva L. E. , Vasukhina I. A. , Mokhort T. V. 
Published: June 2021

Objective:to assess the clinical signiﬁcance of cystatin C in the early diagnosis of diabetic nephropathy.Materials and methods.We examined 449 patients with type 1 and type 2 diabetes mellitusolder than 25 years. The laboratory examination of the patients included the measurement of cystatin, creatinine in the blood serum, GFR calculation according to the CKD-EPI equation, and the determination of albuminuria levels.Results.The role of cystatin C as a reliable marker of diabetic nephropathy has been demonstrated: the level of cystatin C ≥ 0.72 mg/L with sensitivity of 90.8 %, speciﬁcity of 88.9 %, was associated with a decline of renal function in the diabetic patients (ROC AUC = 0.951).Conclusion.The determination of the level of cystatin C, alone or in conjunction with creatinine, will help to more accurately diagnose GFR and assess the risk of mortality and renal complications in patients with diabetes mellitus.
Somatotypical features of the age dynamics of secondary sexual characteristics and functional parameters in city schoolchildren
Authors: Melnik V. A. 
Published: June 2021

Objective:to assess the constitutional features of the age dynamics of secondary sexual characteristics and functional parameters of city schoolchildren in the age range of 7–17 years.Materials and methods.The objects of the study were schoolchildren aged 7–17. The stages of the expression of secondary sexual characteristics were determined visually according to the scheme by J.M. Tanner. The functional parameters of the examined schoolchildren were assessed using the methods of dynamometry, spirometry; blood pressure and heart rates, as well as the time of simple sensorimotor reactions were measured.Results.As a result of the performed studies, it has been found that representatives of the hypersomnic types are ahead of other types to reveal the ﬁrst stages of secondary sexual characteristics. Schoolchildren with the leptosomic morphotypes due to higher rates of their development have reached the deﬁnitive stages by the same age as those with the hypersomnic variants. The intensity of age-related changes in functional parameters (strength qualities, circulatory and respiratory systems, nervous system) in the studied objects depends on their body type.Conclusion.The stage and rate of puberty, as well as the development of functional parameters in city schoolchildren depends on their somatotype.
Screening diagnosis of sleep apnea syndrome in patients with ischemic stroke
Authors: Serebrova E. V. 
Published: June 2021

Objective: to evaluate the effectiveness of the STOP-BANG questionnaire, Berlin questionnaire, and the Epworth sleepiness scale in the screening diagnosis of sleep apnea syndrome in patients with ischemic stroke.Materials and methods. We examined 107 patients (45 women and 62 men; the median age was 64 (56; 74) (aged 36–88). The study involved questioning using the STOP-BANG questionnaire, Berlin questionnaire, Epworth sleepiness scale, and nocturnal respiratory polygraphy.Results. Among 75 patients with sleep apnea syndrome, the STOP-BANG questionnaire, Berlin questionnaire, and the Epworth sleepiness scale showed sensitivity — 91 %, 72 %, 51 %, respectively, speciﬁcity — 53 %, 78 %, 84 %, respectively, diagnostic accuracy — 72 %, 75 %, 68 % respectively, positive predictive value — 82 %, 89 %, 88 %, respectively, and negative predictive value — 71 %, 54 %, 42 %, respectively.Conclusion. The STOP-BANG questionnaire and the Berlin questionnaire are convenient and informative for the screening assessment of the risk of sleep apnea syndrome in patients with ischemic stroke, but their use should be complemented by instrumental diagnostic methods for reliable exclusion of sleep-disordered breathing.
Synthesis, crystal structure, and electrochemical hydrogenation of the La2Mg17-xMx (M = Ni, Sn, Sb) solid solutions
Authors: Kordan Vasyl , Nytka Vitalii , Tarasiuk Ivan , Zelinska Oksana , Pavlyuk Volodymyr 
Published: June 2021

The crystal structure of La2Mg17-xSnx solid solution was determined by single crystal X-ray diffraction for the first time. This phase crystallizes in hexagonal symmetry with space group P63/mmc (a = 10.3911(3), c = 10.2702(3) Å, V = 960.36(6) Å3, R1 = 0.0180, wR2 = 0.0443 for the composition La3.65Mg30Sn1.10) and is related to the structure of CeMg10.3 and Th2Ni17-types which are derivative from the CaCu5-type. A series of isotypical solid solutions La2Mg17-xMx (M = Ni, Sn, Sb, x ~0.8) was synthesized and studied by X-ray powder diffraction, energy dispersive X-ray spectroscopy and fluorescent X-ray spectroscopy. All solid solutions crystallize with the structure related to the Th2Ni17-type. The electrochemical hydrogenation confirmed the similar electrochemical behavior of all studied alloys. The amount of deintercalated hydrogen depends on the physical and chemical characteristics of doping elements and increases in the sequence Sn < Mg < Sb < Ni. The most geometrically advantageous sites are octahedral voids 6h of the initial structure, thus a coordination polyhedron for H-atom is an octahedron [HLa2(Mg,M)4].
UPAYA MENINGKATAN PRESTASI BELAJAR MATEMATIKA MATERI BANGUN RUANG SISI LENGKUNG MELALUI MODEL PEMBELAJARAN INQUIRY PADA SISWA KELAS IX DI SMP NEGERI 70 JAKARTA
Authors: NURKOMARIA NURKOMARIA 
Published: June 2021

Tujuan penelitian dengan menggunakan pendekatan pembelajaran Inquiry diharapkan peserta didik mampu meningkatkan prestasi belajar matematika terhadap materi Bangun Ruang Sisi Lengkung melalui penelitian tindakan kelas yang terdiri atas tindakan siklus I, siklus II dan siklus III. Data yang diambil dalam penelitian ini merupakan data hasil observasi, tindakan siklus I,siklus II dan siklus III serta data pendukung lainnya. Dari hasil penelitian diperoleh data telah terjadi peubahan tingkat prestasi peserta didik menjadi lebih baik. Hal ini terlihat dari perubahan hasil nilai rata-rata kelas dari 60,4 pada siklus 1 hampir sama yaitu 63,1 dengan ketuntasan 14,3% pada siklus II rata –rata hasil belajar menjadi 72,7 dengan ketuntasan 62,5% sedangkan pada siklus III jumlah ketuntasan naik menjadi 87,5 % dengan rata-rata hasil belajar 83,4 . Dengan demikian dapat dikemukakan bahwa pembelajaran dengan menggunakan pendekatan pembelajaran Inquiry mampu meningkatkan prestasi belajar peserta didik terhadap materi Bangun Ruang Sisi Lengkung pada mata pelajaran Matematika di kelas IX SMP N . 70 semester genap tahun pelajaran 2019-2020
Research protocol for homeopathic treatment of congenital zika virus infection
Authors: Mendes Maria Filomena Xavier , Junior Romeu Carillo , Cabo Domingos José Vaz , Gosik Maria Solange , Lino Renata Rodrigues Garcia , Kalile Raquel Bruno , Tavares Davisson , Lacerda Giselle Iannarella , Capobianco Maria Helena , Martins Sandra Motta , Oliveira Paulo Guilherme Leandro , Santos Letícia Werneck dos 
Published: June 2021

Background The Zika virus (ZIKV) is a flavivirus and the human disease caused by this virus has been described in the Americas in 2015. ZIKV has been identified as an etiological agent of acute exanthematous disease in Brazil. In the same year, an epidemic of microcephaly with images suggestive of congenital infection raised the suspicion of a relationship between these alterations and ZIKV infection. Epidemiological and histopathological studies point to a strong relationship between prenatal Zika virus infection and microcephaly. Newborns with microcephaly, may also present auditory and visual changes, seizures and severe neurodevelopmental impairment. In 2016, the World Health Organization (WHO) declared Zika virus (ZIKV) infection a public health emergency of international concern. Aims Clinical observation in the ambulatory school of ABRAH (Brazilian Association of Recycling and Homeopathy Assistance) of patients with encephalopathy of various origins, using the medicine Helleborus niger as equalizer of the NS (Nervous System), as described in the Complex Systems of Carillo, shows improvement in motor, cognitive and seizure disorders. Based on this observation, we propose to use this method in patients with ZIKV congenital infection. Methodology To evaluate 15 patients in follow-up at the AFR (Fluminense Rehabilitation Association), through homeopathic anamnesis, clinical, diathesic, biotypological and temperamental classification. The Gross Motor Function Classification System (GMFCS) will be used. All patients will receive Helleborus niger 6 Ch daily for 6 months. Results and discussion This study was forwarded to the research ethics committee and will begin in July 2019.
Will be evaluated the use of Helleborus niger in patients with congenital infection by ZIKV, as equalizer of NS. The expected result is overall neurological improvement. Conclusion Helleborus niger, probably stimulating self-regulation through uninjured neurological pathways, will promote autopoiesis and construction of new programs of action, and will enable the improvement of patients with congenital ZIKV infection.
Evaluation of the CMIP6 marine subtropical stratocumulus cloud albedo and its controlling factors
Authors: Jian Bida , Li Jiming , Wang Guoyin , Zhao Yuxin , Li Yarong , Wang Jing , Zhang Min , Huang Jianping 
Published: June 2021

Abstract. The cloud albedo in the marine subtropical stratocumulus
regions plays a key role in regulating the regional energy budget. Based on
12 years of monthly data from multiple satellite datasets, the long-term,
monthly and seasonal cycle of averaged cloud albedo in five stratocumulus
regions were investigated to intercompare the atmosphere-only simulations
between phases 5 and 6 of the Coupled Model Intercomparison Project (AMIP5
and AMIP6). Statistical results showed that the long-term regressed cloud
albedos were underestimated in most AMIP6 models compared with the
satellite-driven cloud albedos, and the AMIP6 models produced a similar
spread as AMIP5 over all regions. The monthly averaged values and seasonal
cycle of cloud albedo of AMIP6 ensemble mean showed a better correlation
with the satellite-driven observations than that of the AMIP5 ensemble mean.
However, the AMIP6 model still failed to reproduce the values and amplitude
in some regions. By employing the Modern-Era Retrospective Analysis for
Research and Applications Version 2 (MERRA-2) data, this study estimated the relative
contributions of different aerosols and meteorological factors on the
long-term variation of marine stratocumulus cloud albedo under different
cloud liquid water path (LWP) conditions. The multiple regression models can
explain ∼ 65 % of the changes in the cloud albedo. Under
the monthly mean LWP ≤ 65 g m−2, dust and black carbon dominantly
contributed to the changes in the cloud albedo, while dust and sulfur
dioxide aerosol contributed the most under the condition of 65 g m−2 < LWP ≤ 120 g m−2. These results suggest that the
parameterization of cloud–aerosol interactions is crucial for accurately
simulating the cloud albedo in climate models.
Permanent ectoplasmic structures in deep-sea Cibicides and Cibicidoides taxa – long-term observations at in situ pressure
Authors: Wollenburg Jutta E. , Bijma Jelle , Cremer Charlotte , Bickmeyer Ulf , Zittier Zora Mila Colomba 
Published: June 2021

Abstract. Deep-sea Cibicidoides pachyderma (forma mundulus) and related Cibicidoides spp. were cultured at in situ
pressure for 1–2 d, or 6 weeks to 3 months. During that period,
fluorescence analyses following BCECF-AM
(2′,7′-bis(2-carboxyethyl)-5-(and-6)-carboxyfluorescein acetoxymethyl ester)
or calcein (bis[N,N-bis(carboxymethyl)aminomethyl]-fluorescein) labelling
revealed a persisting cytoplasmic sheet or envelope surrounding the
Cibicidoides tests. Thus, the Cibicidoides shell can be considered as an internal rather than an external cell structure. A couple of days to a week after being transferred
into high-pressure aquaria and adjusted to a pressure of 115 bar, the
foraminifera changed from a mobile to a more or less sessile living mode.
During this quasi-sessile way of life, a series of comparably thick static
ectoplasmic structures developed that were not resorbed or remodelled but,
except for occasional further growth, remained unchanged throughout the
experiments. Three different types of these permanent structures were
observed. (a) Ectoplasmic “roots” were common in adult C. pachyderma, C. lobatulus, and C. wuellerstorfi specimens. In
our experiments single ectoplasmic roots grew to a maximum of 700 times the
individuals' shell diameter and were presumably used to anchor the specimen
in an environment with strong currents. (b) Ectoplasmic “trees” describe
rigid ectoplasmic structures directed into the aquarium's water body and
were used by the foraminifera to climb up and down these ectoplasmic
structures. Ectoplasmic trees have so far only been observed in C. pachyderma and enabled
the tree-forming foraminifera to elevate itself above ground. (c) Ectoplasmic “twigs” were used to guide and hold the more delicate
pseudopodial network when distributed into prevailing currents and were, in
our experiments, also only developed in C. pachyderma specimens. Relocation of a specimen
usually required it to tear apart and leave behind the rigid ectoplasmic
structures and eventually also the envelope surrounding the test. Apparently,
these rigid structures could not be resorbed or reused.
Assessing local impacts of the 1700 CE Cascadia earthquake and tsunami using tree-ring growth histories: a case study in South Beach, Oregon, USA
Authors: Dziak Robert P. , Black Bryan A. , Wei Yong , Merle Susan G. 
Published: June 2021

Abstract. We present an investigation of the disturbance history of an old-growth Douglas-fir (Pseudotsuga menziesii) stand in South Beach, Oregon, for possible growth changes due to tsunami inundation caused by the 1700 CE Cascadia Subduction Zone (CSZ) earthquake. A high-resolution model of the 1700 tsunami run-up heights at South Beach, assuming an “L”-sized earthquake, is also presented to better estimate the inundation levels several kilometers inland at the old-growth site. This tsunami model indicates the South Beach fir stand would have been subjected to local inundation depths from 0 to 10 m. Growth chronologies collected from the Douglas-fir stand shows that trees experienced a significant growth reductions in the year 1700 relative to nearby Douglas-fir stands, consistent with the tsunami inundation estimates. The ±1–3-year timing of the South Beach disturbances are also consistent with disturbances previously observed at a Washington state coastal forest ∼220 km to the north. Moreover, the 1700 South Beach growth reductions were not the largest over the >321-year tree chronology at this location, with other
disturbances likely caused by climate drivers (e.g., drought or windstorms). Our study represents a first step in using tree growth history to ground truth tsunami inundation models by providing site-specific physical evidence.
La microfinance et l'innovation
Authors: LAHROUR Jihane , MAANINOU Amal 
Published: June 2021

La microfinance est une innovation sociale qui porte sur le financement des microentrepreneurs exclus du financement bancaire classique. Et grâce à ce financement qui se fait sous forme de microcrédit, aux bénéficiaires lancent des activités génératrices de revenus, qui leur permettent de s'intégrer dans le circuit économique du pays.
Au Maroc, le microcrédit est un service géré par les associations de microcrédit (AMC) qui placent les besoins en matière de financement des démunis au centre de leurs préoccupations et le microcrédit comme une activité à activité mais non lucratif et les sommes financés par le financement des pauvres, ne sont que pour le financement des charges de fonctionnement de l'AMC (les charges du personnel, le loyer, etc.)
Et puisque les besoins en matière de financement de cette population sont en évolution extrême, L'AMC marocaine lance en continu des innovations commerciales, c'est-à-dire elle développe et innove de nouveaux produits/services financiers adaptés avec les nouveaux besoins de ses bénéficiaires.
Le présent article a pour objectif de répondre à la problématique de l'innovation dans le secteur de la microfinance à travers deux parties, la première opte à la présentation de la microfinance à la chaine internationale et nationale et la deuxième partie traite les grandes lignes de l'innovation dans le secteur bancaire ainsi que le processus d'innovation des AMC non-marocaines.
FAKTOR-FAKTOR YANG BERPENGARUH PADA PENYALURAN KREDIT OLEH BANK YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: Hastuti Andita Tyas Ayu 
Published: June 2021

Analisis rasio keuangan seperti CAR, LDR, NPL, ROA, NIM dan BOPO merupakan salah satu cara untuk menguji apakah rasio-rasio tersebut dapat dijadikan prediksi dalam pemberian kredit. Populasi dalam penelitian ini adalah seluruh bank yang terdaftar di Bursa Efek Indonesia Periode 2011 hingga 2013 sebanyak 33 bank. Setelah melewati teknik purposive sampling, jumlah sampel yang layak digunakan adalah sebanyak 24 Bank Umum. Berdasarkan penelitian diperoleh hasil bahwa variabel capital adequacy ratio (CAR), net interest margin (NIM), dan biaya operasional pendapatan operasional (BOPO) berpengaruh positif dan signifikan terhadap penyaluran kredit. Variabel loan to deposit ratio (LDR) berpengaruh positif tetapi tidak signifikan terhadap penyaluran kredit. Variabel non performing loan (NPL) negatif dan signifikan terhadap pemberian kredit. Variabel return on assets (ROA) berpengaruh negatif dan tidak signifikan terhadap penyaluran kredit. Hasil estimasi dari model yang digunakan dalam penelitian ini menunjukkan bahwa rasio CAR, LDR, NPL, ROA, NIM, dan BOPO mampu menjelaskan tingkat penyaluran kredit sebesar 21,2% sedangkan sisanya 78,8% dipengaruhi oleh faktor lain diluar model yang belum dimasukkan dalam model penelitian.
Kata Kunci: Penyaluran Kredit, CAR, LDR, NPL, ROA, NIM dan BOPO.
Đa dạng loài và phân bố của giun đất ở đảo Phú Quốc, Việt Nam
Authors: Trịnh Thị Kim Bình 
Published: June 2021

Giun đất ở Phú Quốc (tỉnh Kiên Giang) được khảo sát trên 32 điểm thu mẫu ở 2 sinh cảnh rừng tự nhiên và đất trồng. Kết quả ghi nhận 16 loài giun đất thuộc 4 giống và 3 họ. Trong đó, 13 loài lần đầu ghi nhận ở khu vực nghiên cứu là Metaphire houlleti, M. posthuma, M. planata, M. bahli, Amynthas sp.1, A. sp.2, A. sp.3, A. sp.4, A. sp.5; Metaphia sp.1, M. sp.2, M. sp.3 và Drawida sp. Trong ba họ thu được, Megascolecidae chiếm ưu thế tuyệt đối với 14 loài (chiếm 87,50%); Rhinodrilidae và Moniligastridae mỗi họ 1 loài (6,25%). Trong 4 giống thu được, Metaphire chiếm ưu thế với 9 loài, Amynthas với 5 loài. Pontonscolex corethrurus, M. bahli và M. planata có độ phong phú cao nhất. Độ tương đồng về thành phần loài giữa hai sinh cảnh cao (> 80%).
Khảo sát đặc điểm hình thái, sinh học, ký chủ và khả năng ăn mồi của bọ rùa Coccinella transversalis trên rau màu
Authors: Trần Văn Khải 
Published: June 2021

Kết quả khảo sát ghi nhận chu kì sinh trưởng của Coccinella transversalis biến động từ 25-66 ngày, thời gian ủ trứng là 3,69 ngày, giai đoạn ấu trùng là 11,6 ngày (có 4 tuổi), thời gian làm nhộng là 3,27 ngày. Tuổi thọ của thành trùng đực và thành trùng cái lần lượt là 18,1 ngày và 29 ngày với thời gian tiền đẻ trứng là 3-5 ngày. Con cái đẻ trứng trung bình là 212 trứng, với tỉ lệ trứng nở khá cao (80,12%). Tần số xuất hiện của bọ rùa C. transversalis trên cây bầu và cây ớt nhiều nhất. Bọ rùa C. transversalis có khả năng ăn rầy mềm (Aphis craccivora và Aphis glycines) ở cả 4 giai đoạn ấu trùng và thành trùng. Bọ rùa C. transversalis tỏ ra có triển vọng trong công tác phòng trừ sinh học rầy mềm.
Triết lý nhân sinh của J.Krishnamurti và giá trị thực tiễn đối với việc giáo dục nhân văn cho con người Việt Nam trong giai đoạn hiện nay
Authors: Nguyễn Thị Hồng Yến 
Published: June 2021

Krishnamurti là một nhà triết học nhân sinh lớn của thế kỷ XX. Triết học của ông đặt ra những vấn đề không chỉ là sự quan tâm của đương đại mà của mọi thời đại vì đó là những vấn đề muôn thuở của con người như số phận, sự hiện hữu, sự siêu việt và sự tha hóa… Theo ông, nguyên nhân gây ra sự tha hóa của con người trong xã hội phương Tây hiện đại là do cái tôi có nhiều ham muốn ích kỷ cá nhân. Ông đưa ra những giải pháp khuyên nhủ con người nên sống để thanh tẩy tâm hồn cá nhân và xã hội như là “đời không tâm điểm“, “Sống là hiện tượng không thời gian, tri là không suy niệm và hành động không chủ đích”. Thực chất đây là các giải pháp tâm linh, thiên về lay động, đánh thức thế giới nội tâm, đánh thức sự tự ý thức của cá nhân trong cuộc nhân sinh. Tuy không phải là cách làm mới trong lịch sử triết học và có phần duy tâm nhưng đóng góp quan trọng nhất của Krishnamurti là ở chỗ chỉ ra được vấn đề đang nổi cộm trong đời sống của mỗi cá nhân cũng như của xã hội hiện đại ngày nay.
К ИЗУЧЕНИЮ ВОПРОСА О РЕМОНТЕ МАВЗОЛЕЯ ХОДЖИ АХМЕДА ЯСАВИ
Authors: Ёлгин Юрий Андреевич 
Published: June 2021

Неосуществлённый ремонт мавзолея Ходжи Ахмеда Ясави, масштабную программу которого в 1906 г. разработал гражданский инженер В.С. Гейнцельман, – это абсолютно неизвестная страница в историографии тимуровского архитектурного шедевра. В данной статье впервые рассматривается проблема финансирования этого проекта, нашедшая отражение во множестве документов, отложившихся в фондах Центрального государственного архива Республики Узбекистан. Анализ этого материала показал отношение к туркестанскому мавзолею самых разных социальных слоёв: от местного духовенства г. Туркестана – до императора Николая II, от передовой научной и творческой интеллигенции – до колониальной бюрократии. В итоге было достигнуто понимание непреходящей научной и художествнной ценности памятника, значения его для верующих Туркестанского края, а также необходимости сохранения его для будущих поколений.
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