bluuebunny/crossref_metadata_2025_split huggingface dataset:
Durable Self‐Powered Wireless IoT Machine Condition Monitoring System Based on an Auto‐Switching Non‐Contact Centrifugal TENG
Authors: Mehamud Idiris , Björling Marcus , Marklund Pär , Shi Yijun 
Published: December 2024

AbstractThe long‐term intelligent machine condition monitoring system is essential in improving maintenance costs and decision‐making. Triboelectric nanogenerator (TENG) has a great advantage in developing self‐powered machine condition monitoring. The main issues preventing TENG for such applications are poor integration to machine components, limited operational range, and weak durability. In this work, durable non‐contact TENG energy harvester adaptive is designed to mechanical shafts for harvesting rotational energy. The harvester is designed to automatically switch to the non‐contact mode by using centrifugal force to avoid manual switching while operating over a wide range of speeds of 0–2000 rpm. The designed TENG generates a high output of up to 25 mW with excellent stability for >20 days of continuous operation and exhibits a high‐power density of 286 W m−3. Moreover, a self‐powered long‐term continuous condition monitoring system is developed from a TENG sensor, energy harvester, and wireless module. The developed system successfully sends possible machine fault frequency every 74 min to the cloud and accessible anywhere. This is the only TENG design reported in the literature that can fully power a Wi‐Fi module to send data. Hence, the result promises the practical application of the system in developing internet of things (IoT) in the Industry.
Fire‐Resistant Carboxylate‐Based Electrolyte for Safe and Wide‐Temperature Lithium‐Ion Batteries
Authors: Yang Yi , Yao Nan , Yao Yu‐Xing , Xu Lei , Wen Xue‐Fei , Li Zeheng , Yang Zhuo‐Lin , Yan Chong , Huang Jia‐Qi 
Published: December 2024

AbstractThe combustion accident and narrow temperature range of rechargeable lithium‐ion batteries (LIBs) limit its further expansion. Non‐flammable solvents with a wide liquid range hold the key to safer LIBs with a wide temperature adaptability. Herein, a carboxylate‐based weak interaction electrolyte is achieved by molecular design, which consists of EDFA (ethyl difluoroacetate), 1,1,2,2‐tetrafluoroethyl‐2,2,3,3‐tetrafluoropropylether, and fluoroethylene carbonate. The inherent non‐flammable and wide liquid‐rang features of the electrolyte ensure the safety as well as the wide operating temperature of a battery. The high affinity between FSI− anions and counter Li+ guarantees a stable and inorganic‐components‐dominated electrolyte/electrode interphase with rapid Li+ de‐solvation kinetics, leading to perfect compatibility with graphite and avoiding side reactions between lithiated graphite and electrolyte. The rationally designed EDFA‐based electrolyte enables the thick graphite (4.4 mAh cm−2) || LiNi0.8Co0.1Mn0.1O2 (4.0 mAh cm−2) cells to operate efficiently in a wide temperature range from −30 to 45 °C. The proposed EDFA‐based electrolyte enables the commercial 1.0 Ah graphite || NCA (LiNi0.8Co0.15Al0.05O2, >3.2 mAh cm−2) pouch cells stably cycle for >1100 cycles (>85% capacity retention) at 0.3C and >800 cycles at 1.0C (>92% capacity retention), while also endows the graphite/SiOx and Li anode‐based batteries with high energy density, long lifespan and high safety.
Designing Copolymeric SEI Layer Based on Click Reaction toward Ultralow N/P Ratio and Long Cycle Life Zinc Ion Batteries
Authors: Liu Baohua , Ma Xue , Wang Qinghong , Zhang Shilin , Yuwono Jodie , Jin Huanyu , Qiu Juan , Ma Houyi , Wang Chao , Lai Chao 
Published: December 2024

AbstractBalancing interfacial interactions is critical to the reversibility and cycle stability of Zn ion batteries, as severe chemical corrosion and undesirable hydrogen evolution reaction (HER) are inevitable for Zn anode in aqueous electrolytes during the charge/discharge process. Herein, a multi‐functional copolymeric solid/electrolyte interface (SEI) layer, self‐assembling on Zn anode based on the click reaction between epoxy silane and thioalcohol, is employed to eliminate these side reactions. The dense and robust SEI layer can not only physically repel water from the surface of the Zn anode to effectively inhibit the chemical corrosion and HER but also facilitate the desolvation of Zn2+ to accelerate the kinetic process. Additionally, it also can regulate the interfacial ion flux and induce the preferred Zn plating with (002) crystallographic orientation, enabling dendrite‐free Zn deposition. As a result, a stable Zn anode with a long cycle life of ≈200 h at a depth of discharge (DoD) of 60% is achieved. The Zn||V2O5 full cell delivers a high specific capacity of 165.2 mAh g−1 after 600 cycles at an ultralow N/P ratio (the capacity of the negative electrode to the capacity of the positive electrode) of 2.5. The construction of this robust copolymeric SEI layer provides a new pathway for the development of practical Zn ion batteries.
Enabling Optoelectronics in Harsh Environments: Laser‐Printed Perovskite Films with Exceptional Stability Under Extreme Radiation, Thermal Stress, and Humidity
Authors: Yuce‐Cakir Hurriyet , Dremann Derek , Morel Jarlem L. , Khan Sharmistha , Deconinck Marielle , Shilovskikh Vladimir V. , Nie Wanyi , Vaynzof Yana , Jurchescu Oana D. 
Published: December 2024

AbstractPerovskite optoelectronics are regarded as a disruptive technology, but their susceptibility to environmental degradation and reliance on toxic solvents in traditional processing methods pose significant challenges to their practical implementation. Herein, methylammonium lead iodide (MAPbI3) perovskite films processed via a solvent‐free laser printing technique, that exhibit exceptional stability, are reported. These films withstand extreme conditions, including high doses of X‐ray radiation exceeding 200 Gy, blue laser illumination, 90% relative humidity, and thermal stress up to 80 °C for over 300 min in air. We demonstrate that laser‐printed films maintain their structural integrity and optoelectronic properties even after prolonged exposure to these stressors, significantly surpassing the stability of conventionally processed films. The enhanced stability is attributed to the unique film formation mechanism and resulting defect‐tolerant microstructure. These results underscore the potential of laser printing as a scalable, safe, and sustainable manufacturing route for producing stable perovskite‐based devices with potential applications in diverse fields, ranging from renewable energy to large‐area electronics and space exploration.
Treatment outcomes of hepatectomy and systemic chemotherapy based on oncological resectability criteria for hepatocellular carcinoma
Authors: Komatsu Shohei , Yano Yoshihiko , Ishihara Nobuaki , Kido Masahiro , Gon Hidetoshi , Fukushima Kenji , Urade Takeshi , Yanagimoto Hiroaki , Toyama Hirochika , Fukumoto Takumi 
Published: December 2024

AbstractAimThe oncological resectability criteria for hepatocellular carcinoma (HCC) have recently been established (R/BR1/BR2), and validating the outcomes is an urgent issue. This study aimed to analyze the outcomes of hepatectomy and systemic chemotherapy based on the oncological resectability criteria.MethodsA total of 931 patients in the hepatectomy group and 273 in the systemic chemotherapy group who received atezolizumab/bevacizumab, lenvatinib, or durvalumab plus tremelimumab were recruited.ResultsThe median survival times (MST) in the hepatectomy group were R, 107.2 mo; BR1, 44.4 mo; and BR2, 18.4 mo (p < 0.0001). The MSTs in the systemic chemotherapy group were R, 16.3 mo; BR1, 24.5 mo; and BR2, 16.1 mo (p = 0.3598). A comparison of survival of patients in the BR2 category revealed no significant difference between the two groups for those with modified albumin‐bilirubin grade 1 + 2a (p = 0.7343) and grade 2b + 3 (p = 0.6589). The BR2 definition comprised three tumor factors, and the MST of patients with only one BR2‐defining factor tended to be better in the hepatectomy group than in the systemic chemotherapy group (22.9 vs 20.2 mo, p = 0.0977). Meanwhile, the MST tended to be better in the systemic chemotherapy group than in the hepatectomy group (16.5 vs 12.6 mo) for those with two to three BR2‐defining factors, although the difference was insignificant (p = 0.4252).ConclusionThe oncological resectability criteria for HCC effectively stratified the prognosis after hepatectomy. Treatment outcomes of hepatectomy in patients with two to three BR2‐defining factors are limited, suggesting the need for multidisciplinary treatment.
Hearing Loss Is Associated With Increased Mortality in a Cohort of Older Construction Trades Workers
Authors: Dement John , Ringen Knut , Cloeren Marianne , Almashat Sammy , Grier William , Quinn Patricia , Cranford Kim , Chen Anna , Haas Scott 
Published: December 2024

ABSTRACTBackgroundHearing loss has been associated with increased mortality, and there is evidence that regular use of hearing aids reduces the mortality risk. However, these associations have not been sufficiently studied in worker populations at high risk for noise‐induced hearing loss.MethodsMedical examination data for 19,379 workers employed in US Department of Energy (DOE) facilities were used. Speech‐frequency pure‐tone average hearing loss and hearing aid use were ascertained. Mortality status through 2021 was obtained from the National Death Index. Cox regression examined the association between hearing loss and mortality and the impact of hearing aid use.ResultsEight thousand eighty‐one workers (41.3%) had speech‐frequency hearing loss and 2228 (15.3%) of these workers reported use of hearing aids. A total of 5398 deaths occurred over a median follow‐up of 11.1 years. Hearing loss was an independent risk factor for higher mortality with an adjusted hazard ratio (HR) of 1.10 (95% CI = 1.03−1.17). The HR increased with hearing loss severity but the relationship was non‐linear. Hearing aid users were at 30% reduced risk of mortality compared to those not using hearing aids (HR = 0.70, 95% CI = 0.63−0.77).ConclusionsResults are consistent with research linking hearing loss with increased mortality and the preventive impact of hearing aid use. These findings should inform workers' compensation programs in favor of: (1) better coverage of hearing loss for noise‐exposed workers, and (2) inclusion of hearing aids in medical benefits. Reduction in noise exposures is a priority and workers with hearing loss should be encouraged to use hearing aids.
Prenatal Diagnosis of Proteus Syndrome: About a Case
Authors: Giovannangeli Luana , Magry Virginie , Jobic Florence , Messaoudi Kahia , Darwiche Walaa , Perriere Marianne , Billes Alexis , Delmas Lanta Ségolène , Masurel Alice , Morin Gilles , Jedraszak Guillaume 
Published: December 2024

ABSTRACTProteus syndrome (PS) is a rare disorder (< 1/1000000), marked by progressive overgrowth commonly impacting the skeleton, skin, adipose tissue, and central nervous system. Clinical criteria were established in 2019. PS arises from a somatic activating variation in the AKT1 gene. We report the second case of PS diagnosed prenatally using whole exome sequencing (WES). A 34‐year‐old woman was referred for nonvisualized anterior brain structures and genital anomalies. At 21 weeks of gestation (WG), ultrasonography confirmed brain anomalies, genital anomalies, and macrosomia. Array‐CGH revealed no pathogenic imbalances (arr(X,1‐22)×2). Follow‐up ultrasound (25 WG) and MRI (27 WG) also showed a megalencephaly, leading to WES on amniocytes. The reported mosaic variation in AKT1 was identified. Medical termination of pregnancy occurred at 30 + 1 WG. We present a case of PS confirmed prenatally via WES. To date, six cases of prenatal PS suspicion have been reported, four of which lacked molecular diagnosis. Calculating prenatal clinical scores indicate PS could not be definitively diagnosed without molecular confirmation. Certain features, such as limb malformation and gray matter heterotopia, seem to be significant in prenatal diagnosis. WES, with an average coverage depth of 130X, is valuable for diagnosing suspected PS.
Green Synthesis of Urethane‐Linked Tamarind Seed Xyloglucan: Thermal Stability, Antibacterial Properties, and DFT Study
Authors: Silvadas Jesna Das , Pillai Renjith Sasimohanan , Viswanadhan Girija Resmi , Simi Chandroth Kalyad 
Published: December 2024

ABSTRACTThis study presents a feasible, one‐pot synthesis approach for the preparation of a composite biopolymer material derived from tamarind seed xyloglucan (XG) by utilizing isocyanate chemistry. Through a facile reaction process, urethane bonds are formed in XG, resulting in the formation of a crosslinked network. FTIR spectra confirm the successful urethane link formation in XG via the OH‐NCO reaction, and CHN analysis provides insights into the elemental composition. The synthesized XG‐urethane composite (U‐XG) exhibits enhanced thermal stability compared to native XG, with an enhanced degradation temperature (T5%) of 276°C (XG marked T5% at a lower temperature of 163°C). The optimized geometric structure, hydrogen bond types, and hydrogen bond strength of the synthesized U‐XG are computationally studied by density functional theory (DFT) at the B3LYP/6‐31G(d,p) level. This study also investigates the antibacterial efficacy of both XG and U‐XG against a panel of pathogenic bacteria, including gram‐positive bacteria such as S. aureus and S. epidermidis, as well as gram‐negative E. coli. The U‐XG demonstrates superior antibacterial activity against S. epidermidis compared to pristine XG. This research showcases the feasibility of a one‐pot synthesis approach for preparing urethane‐linked XG with enhanced thermal properties and superior antibacterial activity, offering promising prospects for biomedical and antimicrobial applications.
Comparison of case‐based learning and traditional teaching methods in advanced breast cancer education for oncology residents in the standardized training
Authors: Gui Xinyu , Zhu Anjie , Song Guohong , Li Huiping 
Published: December 2024

AbstractCase‐based learning (CBL) is a learner‐centric educational approach that fosters independent learning and exploration through case analysis, guided by teachers' heuristic instruction. The study aimed to evaluate the efficacy of CBL versus traditional teaching methods in advanced breast cancer education for residents. In this randomized controlled trial, 40 residents undergoing standardized training in the Department of Breast Oncology at Peking University Cancer Hospital were enrolled and were equally divided into CBL and traditional teaching groups. Their performance, self‐assessment, and course satisfaction were evaluated through post‐study examinations and questionnaires. Results showed that the CBL group achieved significantly higher overall scores than the traditional teaching group (88.10 ± 3.72 vs. 85.52 ± 3.27, p = 0.025), with a notable advantage in clinical practice scores (44.54 ± 2.25 vs. 41.83 ± 2.26, p < 0.001). However, theoretical knowledge scores did not differ significantly. Furthermore, the CBL group outperformed in clinical reasoning (p = 0.018), self‐learning capabilities (p = 0.037), and problem‐solving skills (p = 0.037). Satisfaction levels were higher in the CBL group (95%) compared to the traditional group (85%) without statistically significant difference. This study demonstrates the superiority of the CBL method in enhancing the education of residents in advanced breast cancer relative to traditional teaching approaches, supporting the broader application of CBL in medical oncology education.
Electron‐Irradiated Montmorillonite/Polyethylene Composite Separator for High‐Performance Lithium‐Ion Battery
Authors: Kim Sungwoo , Sohel Md Amir , Kim Ji Chan , Cho Sung Oh 
Published: December 2024

ABSTRACTSeparators play a significant role in the safety and performance of lithium‐ion batteries. In this study, composite separators were fabricated using montmorillonite (MMT) as a filler in a high‐density polyethylene (HDPE) matrix, followed by electron irradiation to enhance the safety and performance of separator. Electron irradiation induces chemical bonds by crosslinking between HDPE chains, also between the MMT and HDPE. MMT features a two‐dimensional layered structure with a high surface area, providing abundant crosslinking sites. MMT is treated with a silane coupling agent, which induces layer exfoliation. The exfoliation increases the surface area of MMT, thereby providing more crosslinking sites. Additionally, the surface modification of MMT enhances its affinity with HDPE, leading to better dispersion of MMT within the HDPE matrix. Simultaneously, electron irradiation in an air atmosphere generates polar functional groups, improving the electrolyte affinity of the separator. Consequently, the safety of the MMT composite separator was significantly enhanced, exhibiting a high puncture strength of 0.52 N μm−1 and a thermal shrinkage rate of 21.4% at 135°C for 30 min. Li//LCO cells using the composite separator demonstrated superb cycle stability with a discharge retention of 98.7% and a coulombic efficiency of 99.6% after 200 cycles at 0.5 C, and exhibited rate capability maintaining 74.5% of the capacity at 20 C compared to 0.5 C.
Online monitored characterization of Phocaeicola vulgatus for organic acid production using anaerobic microtiter plate cultivations
Authors: Keitel Laura , Schick Benjamin , Pohen Gino , Yordanov Stanislav , Büchs Jochen 
Published: December 2024

AbstractPhocaeicola vulgatus (formerly Bacteroides vulgatus), an anaerobic gut bacterium, produces several organic acids. Research on P. vulgatus is still in its infancy. However, a detailed understanding of P. vulgatus growth and metabolism is essential for its assessment as an organic acid producer. Media variations, including different initial glucose and NH4Cl concentrations and osmolalities, are significant means to yield higher organic acid titers. Furthermore, examining different nitrogen and carbon sources is important to evaluate the potential of P. vulgatus for growth on renewable resources. Cultivations were performed in an in‐house built device for anaerobic online‐monitoring of fluorescence and scattered light in microtiter plates. Results revealed that the highest organic acid concentrations were reached while using galactose, glucose, or xylose as a carbon source, high osmolalities, and 0.25 g L−1 NH4Cl. In addition, the organic acid composition changed with changing carbon and nitrogen sources. P. vulgatus was successfully further characterized, thereby contributing to a faster characterization of other anaerobic strains and paving the way for anaerobic organic acid production.
Verhalten ausgewählter Elemente in Kleinfeuerungsanlagen
Authors: Flaig Nicole , Eichermüller Johanna , Endriss Felix , Kirchhof Rainer , Thorwarth Harald 
Published: December 2024

ZusammenfassungDie Konzentrationen ausgewählter Elemente in Holzhackschnitzeln und in deren Aschen wurden nach der Verbrennung in einer Holzfeuerungsanlage mit einer Leistung von 300 kWth mittels ICP‐OES (induktiv gekoppeltes Plasma‐optische Emissionsspektroskopie) bestimmt. Mit den Analysenergebnissen wurden Massebilanzen für die einzelnen Elemente berechnet. Die Wiederfindungsraten der Elemente wurden mit Literaturdaten zur Flüchtigkeit verglichen.
A rapid turnaround time workflow for a cytological liquid biopsy assay using FNA supernatant specimens
Authors: Maher Mohamed H. , Duose Dzifa Y. , Wistuba Ignacio I. , Luthra Rajyalakshmi , Arjuna Srividya , Roy‐Chowdhuri Sinchita 
Published: December 2024

AbstractBackgroundGenomic profiling is essential in the management of non–small cell lung cancer. However, this may often be challenging because of limited cytological tissue and extended turnaround time (TAT) for next‐generation sequencing (NGS). This study aims to describe a rapid TAT workflow for molecular profiling using fine‐needle aspiration (FNA) supernatants.MethodsA fully automated total nucleic acid extraction using the Genexus Integrated System was compared to a manual extraction using FNA supernatants from 50 patients with non–small cell lung cancer. Molecular profiling using the 50 gene Oncomine Precision Assay GX panel was performed and NGS results were compared with those of paired tissue samples.ResultsThe FNA samples processed using the automated Genexus purification system (n = 42) and the manual extraction method (n = 8) showed comparable quality control metrics with a median total nucleic acid yield of 1230 ng (18–17720 ng) and 1068 ng (777–1740 ng), respectively. The Genexus purification system reduced the hands‐on time from 120 to 30 minutes, enhancing workflow efficiency and decreasing the overall TAT. Of the 50 samples extracted, NGS was performed on 26 samples: seven via manual extraction and 19 using automated extraction. NGS quality control metrics were also comparable between both extraction methods. The overall TAT of the automated NGS workflow from specimen received to test result was 24 hours, providing rapid and reliable molecular results for timely clinical decision‐making and improved patient outcomes.
Effects of Congestion in Human Lung Investigated Using Dual‐Scale Porous Medium Models
Authors: Thangavelu Aarthi , Narasimhan Arunn 
Published: December 2024

ABSTRACTChronic obstructive pulmonary disease (COPD) is a primary chronic respiratory disease associated with pulmonary congestion that restricts airflow and thereby affects the exchange of gases between the alveoli and the blood capillaries in the lungs. Dual scale—global and local—porous medium models have been developed and reported in this work, to study the effects of air‐side congestion on the blood‐oxygen content in the alveolar region of the human lung. The human lung is model as a global, equivalent, heterogeneous porous medium comprising three zones with distinct permeabilities related to their progressively complex branching structure. Airflow for each breathing cycle is determined by solving mass and momentum transfer equations across the three porous medium zones. The congestion is introduced by appropriate modification of the porous medium properties of the zones considered. The congestion‐affected air velocity reaching Zone 3 is given as input to a separate “local model” employed at several locations of the alveoli of Zone 3. The local model determines the oxygen content in the blood flow in the capillaries of the alveoli by solving suitable mass, momentum and species transport equations. The transient simulation results performed for a long duration of multiple breathing cycles, demonstrate that a normal, healthy human lung is functional for up to 40% volume congestion or when 50% of the lung is congested to about 23.5%. Increasing congestion beyond this value, quickly—within a few hours—depletes the oxygen exchange in the blood flow of the alveolar region (of Zone 3), leading to hypoxemia. The effects of congestion progression on oxygen exchange dynamics determined through the dual‐scale porous medium modelling approach provide researchers and medical professionals with in silico predictive estimates to generate treatment strategies for chronic respiratory diseases.