bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical mimics and diagnostic challenges in tick-borne borreliosis: a systematic review
Authors: Blazhnyaya L. P. , Avdeeva M. G. , Moshkova D. Yu. 
Published: April 2021

Background. Ixodes tick-borne borreliosis (TBB) is a clinically multifaceted disease posing a serious threat in most territories of the Russian Federation. New TBB outbreaks emerge and spread to the country’s south.Objectives. The review highlights the TBB clinical diversity to physicians in order to improve the diagnosis quality and opportune aid. It focuses on the early and late clinical presentation of localised and disseminated polysystemic TBB.Methods. Sources were mined in the MEDLINE, PubMed and national electronic databases (Сyberleninka, eLibrary, etc.) with keywords “tick-borne borreliosis” [клещевой боррелиоз], “Lyme disease” [болезнь Лайма], “Lyme arthritis” [Лайм-артриты], neuroborreliosis [нейроборрелиоз] for the period of 2014–2020. Selected impactive publications within 2007–2013 were also included. Research was considered eligible if borreliosis was diagnosed using specific techniques like immune-enzyme assays, immunoblotting or PCR.Results. TBB is a common and cross-disciplinary situation. The disease may progress occult or manifest in a variety of forms, from annular erythema to cardiac, peripheral and central nervous system involvement or arthritis. The polysystemic nature of lesions, often long-term of the tick bite, forces multiple specialist visits ending with misdiagnoses, late aetiotropic therapy and transition into a chronic phase through ignorance of the patient’s epidemiological record. Some patients may have the acute phase followed by irreversible neurological damage associated with memory loss, cognitive decline, arthrosis and sclerotic skin change reducing the quality of life.Conclusion. TBB can be mimicked by therapeutic, neurological, skin and ophthalmic illnesses, which warrants the physician’s attention to the epidemiological record and knowledge of specific diagnostic techniques. Further research is necessary into the pathogenesis and clinical presentation of chronic TBB and its residual manifestations.
Bullet retrieval from the cauda equina after penetrating spinal injury: A case report and review of the literature
Authors: Ojukwu Disep I. , Beutler Timothy , Goulart Carlos R. , Galgano Michael 
Published: April 2021

Background:
When gunshot injuries occur to the spine, bullet fragments may be retained within the spinal canal. Indications for bullet removal include incomplete spinal cord injury, progressive loss of neurologic function including injury to the cauda equina, and dural leaks with impending risk of meningitis.

Case Description:
Here, we present a 34-year-old male with a missile penetrating spinal injury to the cauda equina. In addition to the computed tomography scan demonstrating retention of a bullet in the left L1/2 disc space, the scan suggested likely dural injury. The patient underwent a decompression/instrumented fusion with retrieval of the retained bullet fragment. A laminectomy was performed from T12 to L3, and at L1 and L2, a large traumatic durotomy was identified and repaired. The patient, unfortunately, continued to have bilateral lower extremity plegia with neurogenic bladder/bowel dysfunction at 1-year follow-up.

Conclusion:
We discuss the operative management and provide an intraoperative video showing the bullet extraction and dural closure.
Pathological axis fracture secondary to a solitary bone plasmacytoma: Two cases and a literature review
Authors: Yurac Ratko , Silva Alvaro , Delgado Matias , Nuñez Marilaura , Lopez Juan , Marre Bartolome 
Published: April 2021

Background:
Solitay bone plasmocytoma (SBP) account for just 5–10% of all plasma cell neoplasms. They are infrequent in the cervical spine, especially involving the C0–C2 segment. In this article we conducted a literature review and present the diagnosis, management and long term course of two patients with SBP of C2 causing cervical instability.

Methods:
We assessed the clinical records of two patients with SBP in C2 and cervical instability attributed to SP-B involving C2. Both patients presented with progressive, severe cervicalgia, and the “sensation” of skull instability. Magnetic resonance imaging revealed an extensive, infiltrative lesion involving C2 vertebral body and lateral masses, consistent with a plasmacytoma.

Results:
Both patients underwent emergency posterior surgical stabilization with craniocervical fixation; this was accompanied by a C2 transpedicular biopsy. Postoperatively, patients exhibited no focal neurological deficits and rapidly became pain free. They additional recieved 25 sessions of local conventional radiation therapy. Both patients are doing well as respective 2 and 7-year follow-up.

Conclusion:
Although rare, unstable SBP may present atypical cervical location that readily responds to surgical descompression/fusion and radiotherapy.
Intraparenchymal subependymoma: Case report and literature review
Authors: Lopes Othavio Gomes , Du Pin Almeida Felipe Calmon , Cabral Gustavo Augusto Porto Sereno , Guimaraes Rodrigo Dias , da Silva Filho Ruy Castro Monteiro , Landeiro Jose Alberto 
Published: April 2021

Background:Intracranial subependymomas are rare slow-growing benign tumors typically located in the ventricular system, accounting for 0.07–0.7% of all intracranial neoplasms. Intraparenchymal subependymoma is extremely rare lesions, imposing a challenging diagnosis and management.Case Description:We describe a case of a supratentorial intraparenchymal mass on left occipital lobe in a 26-year-old woman with progressive headache and visual impairment. Differential diagnosis mainly included gliomas, neuronal-glial tumors, ependymoma, and subependymoma. Complete surgical resection was performed and histopathology analysis confirmed diagnosis of subependymoma. Despite its benign behavior the Ki67/MIB-1 labeling index assessed by immunohistochemistry was 5%. After 1 year of follow-up she was free of tumor recurrence.Conclusion:Intraparenchymal subependymoma is extremely rare tumors and literature review showed only 11 cases reported. In general, they are misdiagnosed as other tumors, so careful attention on clinical and radiological features must be taken when looking at a tumor close to the ventricular system, even though it does not have any obvious direct connection to it. Despite its benign nature, total removal must be attempted given that there are reports of recurrence, especially in partially removed tumors with high proliferation index. The role of adjuvant therapy is still limited and new treatment options are being developed as our knowledge on biological and molecular characteristics advances.
Intracranial arachnoid cysts in an infant: A technical note on the innovative use of navigation and flexible endoscopy for cyst fenestration
Authors: Sprau Annelise Claire , McCrea Heather J. 
Published: April 2021

Background:
Intracranial arachnoid cysts (ACs) are a cerebral spinal fluid (CSF) collection within the meninges. They typically arise during embryologic development. Some are stable overtime with little consequence, but large or growing cysts may require surgical intervention. The optimal surgical technique is debated and may be more technically challenging in the infant age group.

Case Description:
Our unique case report details a 10-month-old (6 months corrected age) infant who presented with a drastic increase in head circumference and was found to have midline shift and three cysts – one large and two smaller ones. He was treated with an innovative surgical approach combining stereotactic introduction of a catheter to facilitate subsequent flexible endoscopy allowing three separate cysts to be treated through one small surgical incision with no complications and a stable examination on 2-year follow-up.

Conclusion:
Symptomatic ACs in the infant population that require treatment can be addressed with open surgery to fenestrate the cyst, endoscopic cyst fenestration, or cystoperitoneal shunting. Typically, surgeons must choose between a rigid endoscope which allows stereotactic navigation or a flexible endoscope which allows multiple trajectories but precludes navigation. Our case demonstrates that combining stereotactic ventricular placement before flexible endoscopy provides the benefit of both approaches and allows for successful endoscopic treatment in a young patient with durable results.
Can blood pressure be measured without undressing patients ?
Authors: Durand Pierre-Yves , Le Hegarat Typhaine , Gutter Thibault 
Published: April 2021

The guidelines recommend that the technique of measuring arterial blood pressure requires positioning the cuff on a bare arm, without rolled-up sleeve. These recommendations are sometimes difficult to apply in routine practice, as in dialysis centers where the measurement is repeated in fragile patients. In this study, we assess the validity of the blood pressure measurement with a cuff positioned on a bare arm, compared to a cuff positioned on several layers of clothing.
A total of 1,224 blood pressure measurements were taken in 51 dialysis patients over a period of one month, 6 measurements per week, i.e. 24 measurements per patient. The patients wore their ordinary clothes suitable for a winter season. Thus, 612 measurements were taken with a cuff on a bare arm, and 612 measurements with a cuff on clothing. The mean systolic pressures were 121.9 and 123.5 mmHg, respectively when the cuff was placed on clothing and bare skin. The mean diastolic pressure was 60.1 and 60.5 mmHg, respectively. The observed difference does not reach the level of statistical significance with respectively p = 0.168 and p = 0.135. The same is true for mean arterial pressure, with 80.6 and 81.5 mmHg respectively (p = 0.142). The difference observed does not justify the undressing of patients for whom this procedure is difficult, uncomfortable or painful.
Caracterização dos casos de tuberculose notificados em um município prioritário do Brasil
Authors: Maria Melo Guimarães dos Santos Tatiana 
Published: April 2021

DOI: https://doi.org/10.26694/reufpi.v1i1.703
Trata-se de um estudo transversal que objetivou descrever as características dos casos de tuberculose notificados em 2008, em Teresina, no Sistema de Informação de Agravos de Notificação. Dos 684 casos, 74,7% são de residentes no Piauí e 20,8% no Maranhão. Dentre os 511 casos de residentes no Piauí, 67,1% são de Teresina. A proporção de pacientes com a forma pulmonar foi de 79,3%. Quanto ao desfecho, 60,3% dos pacientes evoluíram para cura e 3,5% abandonaram o tratamento. A associação do desfecho e estratégia de tratamento foi estatisticamente significativa p=0,001. Observou-se a centralização do diagnóstico na Referência Terciária. Verificou-se que o grande número de doentes residentes em outros municípios dificulta o encerramento dos casos, além de prejudicar a avaliação de indicadores quando se tem como parâmetro o sistema de informação. Assim, o controle da tuberculose depende de melhoria dos fatores relacionados aos serviços de saúde como um sistema de informação confiável.
Імітаційна модель оцінювання ефективності систем залпового вогню
Authors: Звиглянич С.М. , Кошель А.В. , Линник М.Ф. , Руденко Д.В. 
Published: April 2021

На сьогодні системи залпового вогню представляють бойові платформи, що широко використовуються в Сухопутних військах при веденні усіх форм і видів бойових дій. Вдосконалення систем залпового вогню, підвищення їх бойової ефективності є важливим науково-технічним завданням. Предметом розгляду статті є спосіб оцінювання ефективності застосування систем залпового вогню. Запропонований підхід оцінювання ефективності систем залпового вогню на основі імітаційної моделі, що значною мірою спростило розробку математичної моделі даного процесу. Основним чинником, що впливає на процес ураження площадкових цілей, який розглядається в моделі, є точність прицілювання. Результатом роботи моделі є визначення, залежно від точності, долі зони ураження, що потрапила під дію вражаючих елементів бойових блоків. Початкові дані, що використовуються в моделі, мають ясний фізичний сенс, відображають процес ураження площадкової цілі системою залпового вогню і є обчислюваними. Запропонована імітаційна модель дозволяє проводити кількісну оцінку варіантів ураження заданої площі при плануванні бойових операцій.
IMPLEMENTASI TEKNOLOGI 3D AUGMENTED REALITY UNTUK PEMETAAN KAMPUS UNISKA MAB
Authors: Setiawan Indra , Hijriana Nadiya 
Published: April 2021

ABSTRAK Universitas Islam Kalimantan Muhammad Arsyad Al Banjari Banjarmasin atau UNISKA MAB adalah salah satu perguruan tinggi swasta yang cukup banyak diminati oleh masyarakat di Kalimantan. Untuk kegiatan promosi maupun pengenalan kampus, UNISKA MAB masih memakai cara lama seperti lewat spanduk (baliho), media cetak maupun lewat informasi secara online di website resmi UNISKA MAB. Sedangkan untuk mahasiswa baru, informasi tentang kampus secara detail dirasakan masih kurang walaupun pada kegiatan Pengenalan Kehidupan Kampus Mahasiswa Baru (PKKMB), mahasiswa baru memperoleh buku pedoman tentang kampus UNISKA MAB, namun dirasakan masih kurang efektif. Hal ini dibuktikan dengan masih adanya mahasiswa baru yang kebingungan mencari lokasi ruang perkuliahan, ruang BAK atau ruangan lainnya.Berdasarkan permasalahan tersebut, maka dibuatlah sebuah aplikasi berbasis android dengan menggunakan teknologi AR (Augmented Reality). Dengan adanya aplikasi ini, pengguna terutama mahasiswa baru dapat mengetahui lebih detail tentang lokasi atau ruangan-ruangan yang ada di kampus UNISKA MAB melalui smartphone yang mereka miliki. Selain itu aplikasi yang dilengkapi fitur visual 3D dan audio ini dapat menjadi salah satu alternatif tambahan dalam kegiatan promosi tentang UNISKA ke sekolah-sekolah yang ada di Kalimantan. Kata Kunci : UNISKA, Android, Aplikasi, Augmented Reality
KORELASI PENGETAHUAN MATERI VIRUS DENGAN PERILAKU SISWA SMA MENCEGAH PENULARAN VIRUS CORONA DI KABUPATEN BANGGAI
Authors: HARUNA MOH. FAHRI , NURLIA NURLIA , ASTUTI SRI 
Published: April 2021

Memahami dan menjelaskan perilaku seseorang terhadap suatu materi dapat menggunakan pendekatan teori psikologi tentang hubungan antara pengetahuan, sikap dan perilaku. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan siswa tentang materi virus dengan perilaku siswa SMA dalam mencegah penuaran virus Corona di Kabupaten Banggai. Penelitian ini merupakan penelitian kuantitatif yang bersifat korelasional. Teknik pengambilan sampel dilakukan dengan menggunakan teknik simple random sampling sehingga diperoleh sampel sebanyak 106 siswa SMA kelas X. Teknik pengumpulan data menggunakan angket sebagai instrument yang di berikan secara online. Data dianalisis dengan menggunakan teknik statistik deskriptif dan inferensial. Hasil penelitian menunjukkan bahwa terdapat hubungan yang signifikan antar pengetahuan siswa tentang materi virus (X) dengan perilaku siswa dalam mencegah penularan virus Corona (Y). Kesimpulannya bahwa terdapat hubungan positif antara pengetahuan siswa tentang materi virus dengan perilaku siswa SMA dalam mencegah penuaran virus Corona di Kabupaten Banggai. Hubungan antara kedua variabel tersebut berada pada kategori Rendah.
EVALUATION OF ANTI ULCER ACTIVITY OF HYDROALCOHOLIC LEAVES EXTRACT OF LEUCAS ASPERA
Authors: Kumar Surjeet , Patel Narendra , Budholiya Prabhakar 
Published: April 2021

The main aim of the study was to determine the phytoconstituents present in Leaves of Leucas aspera. The present study was therefore carried out to evaluate the anti-ulcer activity of Hydroalcoholic (70% methanol) leaf extract of Leucas aspera in rats. The effect of Leucas aspera extract on gastric ulcer in rats in indomethacin induced gastric ulcers model and ethanol-induced models was studied using single dosing (100, 200 mg/kg) and repeated dosing (200 mg/kg for 5 days) approaches. Ranitidine (50 mg/kg) and cimetidine (100 mg/kg) were used as the standard drugs. Depending on the model, outcome measures were volume ulcer index. Data were analyzed using one-way analysis of variance and P<0.05 was considered as statistically significant. Leucas aspera significantly (P<0.001) reduced gastric ulcer, respectively, in indomethacin induced gastric ulcers model and ethanol-induced models at the 200 mg/kg dose, which is comparable to the standard drugs. 5 days pre-treatment with Leucas aspera 200 mg/kg exhibited significant (P<0.001) ulcer inhibition. Leucas aspera possesses both dose-dependent and time-dependent anti-ulcer effect in the two models. The oral median lethal dose (LD50) is estimated to be higher than 2000 mg/kg for the crude hydroalcoholic extract, and secondary metabolites such as flavonoids, tannins, and saponins were present. The findings of this study confirmed that Leucas aspera has anti-ulcer pharmacologic activity due to one or more of the secondary metabolites present in it. Therefore, this study validates its anti-ulcer use in Ethiopian folk medicine. Further investigations on isolation of specific phytochemicals and elucidating mechanisms of action are needed.
Створення технологічної схеми процесу отримання етилену з біоетанолу в умовах аерозольного нанокаталізу за допомогою програми ChemCad
Authors: Міщенко С.О. , Глікіна І.М. , Глікін М.А. 
Published: April 2021

Дана робота дає можливість розглянути можливість теоретичних розрахунків на моделі хімічного перетворення етилового спирту в етилен за допомогою програмного комплексу ChemCad. Були розглянуті різні концентрації вихідної сировини з метою отримання цільового продукту від параметрів реакції: температура, тиск, концентрація.
Робота є розширенням можливості застосування нової перспективної технології аерозольного нанокаталізу. Технологія добре зарекомендувала себе як в процесах глибокого окислення, які знаходять застосування в екологічному напрямку при знешкодженні різних відходів, так і деяких процесах синтезу, наприклад синтез Фішера-Тропша (отримання вуглеводнів з синтез-газу).
Serum Iron Profile in Chronic Renal Failure Patients
Authors: Miah Md Helal , Hossain Md Zakir , Das Bidhu Bhusun , Sarker Md Mokhlesur Rahman , Saha Sumanta Kumar , Haque Md Ashraful , Yusuf Md Ghulam 
Published: April 2021

Background & objective: Chronic Renal Failure (CRF) is a serious condition with a worldwide impact. Anemia is a common complication of CRF leading to significant morbidity. Iron deficiency may be a contributing factor for developing anemia in CRF patients. It may be particularly problematic during erythropoietin therapy. This study was intended to find the serum iron status in CRF patients.
Method: This cross sectional study was conducted on 100 consecutive patients of CRF in the Department of Medicine, Rangpur Medical College & Hospital, Rangpur and Hypertension & Research Centre, Rangpur between July 2010 to June 2012.
Result: 40% of the patients were 40-59 years old, 28% were 20 - 39 years and 32% >60 years old. Males were predominant (64%) than the females (36%). None of the biochemical variables (serum creatinine, haemoglobin and serum iron profile), except total iron binding capacity (TIBC) differ by sex. TIBC was significantly higher in females than that males (p = 0.029). Of the 100 patients 40% were iron deficient; of them 12(30%) had absolute iron deficiency and 28(70%) relative iron deficiency. Iron deficiency was not influenced by sex (p = 0.519). It was not even affected by the degree of renal insufficiency (p = 0.524). However, the incidence of severe anemia increases significantly with the degree of renal insufficiency (p = 0.037).
Conclusion: Serum iron profile remains normal in most of the cases of CRF patients. It should be investigated in every CRF patients before deciding for iron therapy.
Ibrahim Cardiac Med J 2012; 2(2): 8-13
Study on Serum Levels of Thyroid Hormones and Thyroid Stimulating Hormone in Different Trimester of Normal Pregnancy
Authors: Begum Zinat , Banu Rezina Akhtar , Moon TH Zahra Moon 
Published: April 2021

Objective: The present study was conducted to study the changes in serum levels of thyroid hormones and thyroid stimulating hormone (TSH) in different trimesters of normal pregnancy.
Methods: This cross-sectional study was conducted in the Department of Physiology, Rangpur Medical College Hospital over a period 1 year from July 2008 to June 2009. Apparently healthy pregnant women aged between 20 - 35 years were consecutively included in the study. Patients suffering from thyroid disorders or any other systemic diseases and lactating mothers were excluded from the study. A total of 100 subjects - 75 pregnant women (25 selected from each trimester of pregnancy) and 25 non-pregnant women were purposively selected as case and control groups respectively.
Result: The mean age was almost identically distributed between the two groups (23.8 ± 3.9 vs. 24.9 ±4.6, p = 0.343). Lower class patient was predominant in case and control group (68% vs. 64%, p =0.756). The mean serum T3 level was higher in case group compared to control group. The mean serum T3 level was identically distributed in 1st and 3rd trimester (p = 0.536 and p = 0.145 respectively) but significant difference was found in 2nd trimester (p = 0.001). The mean serum T4 level of control group did not experience any change throughout the whole observation period. The serum T4 level was 210 nmol/L at 1st trimester then it began to increase almost a plateau at 2nd trimester and then gradually dropped 232.2 nmol/L at third trimester. The mean serum TSH level was 1.1 mIU/L at 1st trimester then it began to increase sharply assumed a mean score 1.3 mIU/L at 2nd trimester. From 2nd trimester onwards it began to decrease upto the end of observation when no change in the non-pregnant women in 1st, 2nd & 3rd trimester.
Conclusion: Thyroid hormones (T3, T4) increase in the 2nd trimester of pregnancy and fall again in the 3rdtrimester but TSH does not experience any significant change throughout the pregnancy.
Ibrahim Cardiac Med J 2012; 2(2): 19-23