bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Kemampuan Berpikir Kreatif Matematis Siswa Dalam Menyelesaikan Masalah Sistem Persamaan Linear Tiga Variabel
Authors: Triyani Ita , Azhar Ervin 
Published: November 2021

Kemampuan berpikir kreatif adalah kemampuan menemukan banyak cara atau alternatif jawaban untuk menyelesaikan suatu permasalahan. Indikator kemampuan berpikir kreatif yang digunakan adalah kefasihan, fleksibilitas dan kebaruan. Tujuan penelitian ini adalah untuk mengetahui seberapa jauh kemampuan berpikir kreatif matematis siswa dalam menyelesaikan masalah sistem persamaan linear tiga variabel. Jenis penelitian ini adalah penelitian kualitatif deskriptif. Penelitian ini dilaksanakan di SMA Negeri 15 Jakarta. Subjek penelitian ini adalah kelas X IPA 3. Instrument yang digunakan adalah berupa tes kemampuan berpikir kreatif yang berbentuk soal uraian pada materi sistem persamaan linear tiga variabel. Hasil dari penelitian ini adalah dari ketiga siswa yang diteliti dan diwawancarai lebih mendalam hanya ada satu siswa yang memenuhi ketiga aspek kemampuan berpikir kreatif menurut silver dan dari 22 siswa yang mengerjakan tes dan setelah diteliti hasil jawabannya ada 12 orang yang memiliki kemampuan berpikir kreatif rendah. Maka dapat disimpulkan bahwa kemampuan berpikir kreatif siswa tergolong rendah.
Anomalous Cognition
Authors: Tressoldi Patrizio , Storm Lance 
Published: November 2021

Objective: The aim of this study was to assess the results of all meta-analyses on anomalous cognition conducted between 1989 and 2021 in order to find moderators associated with greater effect sizes. Method: We included all meta-analyses of studies related to anomalous cognition published up to 2021. Results: Our dataset, accumulated over more than 80 years of investigation, refers to 11 meta-analyses related to six different states of consciousness. The evidence clearly shows that anomalous cognition seems possible and its effects can be enhanced by using a combination of some non-ordinary or altered states of consciousness (e.g., dreaming, ganzfeld, etc.), coupled with free-response procedures, or neurophysiological dependent variables. These conditions facilitate an alternative form of cognition seemingly unconstrained by the known biological characteristics of the sense organs and the brain. Conclusion: The accumulated evidence expands our understanding of the mind-brain relation and the nature of the human mind.
Analysis of Deixis in the Iraqi Constitution of 2005
Authors: Jaber Hussein Saeed , M. Almawla Fida 
Published: November 2021

The concept of deixis is one of the most important topics in the pragmatic analysis that needs to be clarified; deixis is used to analyse the text, utterance or sentence because every utterance is a reference used to pointing about people, something, place or time. The meaning of this utterance will be clear when the listeners or readers know about who, where and when the utterance is uttered. The current study aims at clarifying Deixis that exist in the Iraqi Constitution of 2005 and how the constitutional makers use these elements in the selected articles. To achieve the aims of the study, several articles have been selected from the Constitution as data to be analysed and a qualitative methodology has been employed in analyzing the collected data based on Levinson (1983). It has been hypothesized that the ordinary readers of the Iraqi Constitution face difficulty in understanding the meaning of a lot of the articles of the constitution because there are false and misuses of the deictic expressions. The study has come up with the results that deictic expressions are widely used in the Iraqi Constitution to convey certain aims. The use of such linguistic and pragmatic elements is proved to have an obvious impact on ordinary peoples’ understanding of the legal document.
القدرة التبؤية للبنى المعرفية اللاتكيفية في تحديد زملة التعب العصبي المزمن لدى المتعافين من الاصابة بفايروس كوفيد-19
Authors: هارون رشيد فارس 
Published: November 2021

هدفت هذه الدراسة الى التعرف على القدرة التبؤية للبنى المعرفية اللاتكيفية في تحديد زملة التعب العصبي المزمن لدى المتعافين من الاصابة بفايروس (كوفيد-19) واستخدم في البحث الحالي عينة مكونة من 300 متعافا من الاصابة بفيروس كوفيد-19 تراوحت اعمارهم بين (15- 60 سنة )، وتم تطبيق مقياس البنى المعرفية اللاتكيفية الذي اعدته ( منصوري 2019 )الذي يتالف من ( 75 فقرة )، وتبني المقياس العربي لزملة التعب المزمن الذي تم بناؤه وفقا لمعايير منظمة الصحة العالمة ICD من قبل (عبد الخالق والذيب،2006) ، وتألف هذا المقياس من (20) فقرة تهتم بقياس اعراض التعب والانهاك المستمر بعد ان تم التحقق من شروط الصدق والثبات واستعمال الوسائل الاحصائية المناسبة ، وخرجت الدراسة بمجموعة من التوصيات والمقترحات المناسبة لطبيعة نتائج الدراسة الحالية .
العوامل المجتمعية لعمل كبار السن دراسة ميدانية
Authors: حسين علي بروين , حميد حسن حمدية 
Published: November 2021

يعد موضوع كبار السن من الموضوعات المهمة لانها تمثل شريحة اساسية في المجتمع ، والبحث في امورهم وأوضاعهم العامة ليس لأنهم فئة من افراد المجتمع من دون باقي الفئات ، بل ان افراد المجتمع في جميع الاعمار يتطلعون الى كبر السن بوصفها اخر محطة في العمر التي يصاحبها العديد من المشكلات الاجتماعية والاقتصادية والصحية والنفسية ، وهم بهذا العمر بحاجه الى الرعاية ، الا اننا في الواقع نجد منهم من يعمل وهو بهذه المرحلة العمرية ، وعليه فالهدف الرئيس من البحث الحالي هو التعرف على اهم الاسباب المؤدية لعمل كبار السن ، و تشخيص اهم المشكلات التي تواجههم وتمنعهم تحقيق حاجاتهم وتسليط الضوء على دور الرعاية الاجتماعية لكبار السن ، فضلا عن السعي الى لفت انظار الجهات المختصة والمؤسسات الحكومية و دور ايواء المؤسسي للتعرف على واقعهم الاجتماعي والصحي والنفسي لهذه الفئة المهمة في المجتمع ، ، ولأجل التحقق من العوامل المجتمعية التي تساهم في عمل كبار السن فقد قامت الباحثتان باختيار عينة عشوائية بسيطة قوامها (50) مبحوث من كبار السن العاملين في ( علوه جميلة) وبمختلف الأعمار ولم نتمكن من اخذ عينة اكبر نظرا لخوف عدد كبير من كبار السن الذين يعملون من اصابتهم بوباء كورونا ، ولقد تبنى البحث فرضيتين ، أعدت أستبانة لهذا الغرض بوصفها الأداة الأساسية في عملية جمع البيانات ، فضلا عن المقابلات التي أجريت مع المبحوثين ، من خلال استخدام قانون كاي سكوير للوصول إلى طبيعة العلاقة الدالة بين المتغيرات وقد توصل البحث إلى وجود علاقة ذات دلالة احصائية بين عمل كبار السن وإعالة أسرهم بحسب النوع الاجتماعي ، فضلا عن توجد علاقة ذات دلالة إحصائية بين اسباب عمل كبار السن وحالتهم الاجتماعية.
أثر القرآن الكريم في الشعر العباسي
Authors: حازم محمد بشير أكرم 
Published: November 2021

عنيت هذه الدراسة بالكشف عن أثر القرآن الكريم في الشعر العباسي، وقد تبين أن الشعر في العصر العباسي كان يمتاح من المعين القرآني، وأن الشعراء قد استلهموا المعاني والدلالات القرآنية في أشعارهم، وظهر الأثر القرآني في كافة أغراض الشعر العباسي، فقد استلهموا القيم القرآنية في شعر المدح، ووظفوا القيم السلبية في الهجاء، وبرزت أفكار: الصبر، والاحتساب، والدعاء بالفوز بالجنة ومصير الصالحين وغيرها من الأفكار القرآنية في الرثاء، كما تجلى الأثر القرآني في الغزل، على الرغم مما قد يبدو من صعوبة ظهور الأثر القرآني فيه، أما الزهد فقد تجلت فيه الحكم والإشارات القرآنية أكثر مما تجلت في غيره، وزهديات أبي العتاهية هي خير ما يمثل ذلك.
وتجلى الأثر القرآني في التشكيل الفني للشعر العباسي أيضًا؛ فقد وظف الشعراء كثيرًا من ألفاظ المعجم القرآني في شعرهم، كما استلهموا معانيه في تشكيل صورهم وأخيلتهم الفنية؛ مما يعني أن الأثر القرآني قد تجلى في الشعر العباسي، سواء من الناحية الموضوعية أو من الناحية الفنية التشكيلية.
Prospek dan Nilai Tambah Pengolahan Mangga (mangifera indica, l.) Varietas Gedong Gincu Menjadi Kerupuk Pada Home Industri Di Kabupaten Indramayu
Authors: Rivai Sulayman , Hikmana Entus , Karto Karto 
Published: November 2021

Tujuan dari penelitian ini adalah untuk menganalisa nilai tambah pengolahan mangga (Mangifera indica, L.) Varietas Gedong Gincu menjadi kerupuk secara rinci untuk mengetahui (1) besarnya nilai tambah yang dihasilkan dari pengolahan buah mangga menjadi kerupuk pada home Industri Libna Food (2) mengetahui rasio nilai tambah yang dihasilkan dari pengolahan buah mangga menjadi kerupuk pada home Industri Libna Food.
Metode yang digunakan adalah metode survai, dan menggunakan desain survai deskriptif. Untuk penelitian ini tidak di lakukan pengambilan sampel dari populasi karena populasi home industrikerupuk dengan bahan baku mangga hanya satu orang, yaitu Home industry Libna Food satu satunya Home industry yang memproduksi kerupuk mangga berada di Desa Jatisura Kecamatan Cikedung Kabupaten Indramayu.
Berdasarkan hasil penelitian ini usaha pengolahan kerupuk mangga di Home industry Libna Food Desa Jatisura Kecamatan Cikedung Kabupaten Indramayu Tahun 2018.Home industry Libna Food memproduksi kerupuk mangga dengan 1 kemasan, yaitu kemasan yang berisi 250 gram. Dengan nilai tambahnya Rp.10.408 untuk kemasan 250 gram dengan rasio nilai tambahnya sebesar 41.63% dalam satu kali proses produksi.
THE WORLD COMMUNITY CONSOLIDATION FOR COMBATTING WITH POVERTY
Authors: Минигулова Ильмира 
Published: November 2021

Global problems of modern age make deep problems for the formation of socio-economic and political-legal stability in modern states. The most complex is poverty that provokes the new problems, such as the migration crisis. The international community follows the fundamental principles and norms of international law, tries to wipe out poverty, the practical implementation of this activity is reflected in the Concept of Sustainable Development.
Polydopamine Coating-Mediated Immobilization of BMP-2 on Polyethylene Terephthalate-Based Artificial Ligaments for Enhanced Bioactivity
Authors: Kang Zhanrong , Li Dejian , Shu Chaoqin , Du Jianhang , Yu Bin , Qian Zhi , Zhong Zeyuan , Zhang Xu , Yu Baoqing , Huang Qikai , Huang Jianming , Zhu Yufang , Yi Chengqing , Ding Huifeng 
Published: November 2021

Background/objectives: Polyethylene terephthalate (PET)-based artificial ligaments are one of the most commonly used grafts in anterior cruciate ligament (ACL) reconstruction surgery. However, the lack of favorable hydrophilicity and cell attachment for PET highly impeded its widespread application in clinical practice. Studies found that surface modification on PET materials could enhance the biocompatibility and bioactivity of PET ligaments. In this study, we immobilized bone morphogenetic protein-2 (BMP-2) on the surface of PET ligaments mediated by polydopamine (PDA) coating and investigated the bioactivation and graft-to-bone healing effect of the modified grafts in vivo and in vitro.Methods: In this study, we prepared the PDA coating and subsequent BMP-2-immobilized PET artificial ligaments. Scanning electron microscopy (SEM) was used to analyze the morphological changes of the modified grafts. In addition, the surface wettability properties of the modified ligaments, amount of immobilized BMP 2, and the release of BMP-2 during a dynamic period up to 28 days were tested. Then, the attachment and proliferation of rat bone mesenchymal stem cells (rBMSCs) on grafts were examined by SEM and Cell Counting Kit-8 (CCK-8) assay, respectively. Alkaline phosphatase (ALP) assay, RT-PCR, and Alizarin Red S staining were performed to test the osteoinduction property. For in vivo experiments, an extra-articular graft-to-bone healing model in rabbits was established. At 8 weeks after surgery, biomechanical tests, micro-CT, and histological staining were performed on harvested samples.Results: A surface morphological analysis verified the success of the PDA coating. The wettability of the PET artificial ligaments was improved, and more than 80% of BMP-2 stably remained on the graft surface for 28 days. The modified grafts could significantly enhance the proliferation, attachment, as well as expression of ALP and osteogenic-related genes, which demonstrated the favorable bioactivity of the grafts immobilized with BMP-2 in vitro. Moreover, the grafts immobilized with BMP-2 at a concentration of 138.4 ± 10.6 ng/cm2 could highly improve the biomechanical properties, bone regeneration, and healing between grafts and host bone after the implantation into the rabbits compared with the PDA-PET group or the PET group.Conclusion: The immobilization of BMP-2 mediated by polydopamine coating on PET artificial ligament surface could enhance the compatibility and bioactivity of the scaffolds and the graft-to-bone healing in vivo.
Overexpression of NREP Promotes Migration and Invasion in Gastric Cancer Through Facilitating Epithelial-Mesenchymal Transition
Authors: Liu Yuan-jie , Zeng Shu-hong , Hu Yi-dou , Zhang Yong-hua , Li Jie-pin 
Published: November 2021

Graphical Abstract(A) Study Flow chart, (B) Diagram depicting the regulation mechanism of NREP in the tumorigenesis of gastric cancer.
Bacillus subtilis Attenuates Hepatic and Intestinal Injuries and Modulates Gut Microbiota and Gene Expression Profiles in Mice Infected with Schistosoma japonicum
Authors: Lin Datao , Song Qiuyue , Zhang Yishu , Liu Jiahua , Chen Fang , Du Shuling , Xiang Suoyu , Wang Lifu , Wu Xiaoying , Sun Xi 
Published: November 2021

Parasitic infection can induce pathological injuries and impact the gut microbiota diversity and composition of the host. Bacillus subtilis is a nonpathogenic and noninvasive probiotic bacterium for humans and other animals, playing an important role in improving the host immune system’s ability to respond to intestinal and liver diseases and modulating gut microbiota. However, whether B. subtilis can impact biological functions in Schistosoma japonicum–infected mice is unclear. This study used oral administration (OA) of B. subtilis to treat mice infected with S. japonicum. We evaluated changes in the gut microbiota of infected mice using 16 S rRNA gene sequencing and differentially expressed gene profiles using transcriptome sequencing after OA B. subtilis. We found that OA B. subtilis significantly attenuated hepatic and intestinal pathological injuries in infected mice. The gut microbiota of mice were significantly altered after S. japonicum infection, while OA B. subtilis remodel the diversity and composition of gut microbiomes of infected mice. We found that the S. japonicum–infected mice with OA B. subtilis had an overabundance of the most prevalent bacterial genera, including Bacteroides, Enterococcus, Lactobacillus, Blautia, Lachnoclostridium, Ruminiclostridium, and Enterobacter. Transcriptomic analysis of intestinal tissues revealed that OA B. subtilis shaped the intestinal microenvironment of the host responding to S. japonicum infection. Differentially expressed genes were classified into KEGG pathways between S. japonicum–infected mice and those without included cell adhesion molecules, intestinal immune network for IgA production, hematopoietic cell lineage, Fc epsilon RI signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, calcium signaling pathway, Fc gamma R-mediated phagocytosis, chemokine signaling pathway, phospholipase D signaling pathway, NF-kappa B signaling pathway, B cell receptor signaling pathway, pancreatic secretion, and phagosome. In conclusion, our findings showed that OA B. subtilis alleviates pathological injuries and regulates gene expression, implying that B. subtilis supplementation may be a potential therapeutic strategy for schistosomiasis. Our study may highlight the value of probiotics as a beneficial supplementary therapy during human schistosomiasis, but further studies are needed.
Increased Blood Retinol Levels Are Associated With a Reduced Risk of TIA or Stroke in an Adult Population: Lifestyle Factors- and CVDs-Stratified Analysis
Authors: Guo Linjuan , Huang Ying , Wan Rong , Shen Yang , Hong Kui 
Published: November 2021

Background: Data on the existing evidence for the association between blood retinol and transient ischemic attack (TIA)/stroke risk are limited, and the results are inconclusive. This study aimed to further assess the associations between the blood retinol levels and the risk of TIA/stroke after controlling the lifestyle factors and age-related confounders.Methods: The cross-sectional data from 1,113 individuals (aged 34–84 years old) were obtained from the Midlife in the United States (MIDUS) study. The multivariable analyses were performed to investigate the association of blood retinol levels with ever and currently TIA/stroke.Results: There was an inverse association between the blood retinol levels and the risk of ever TIA or stroke (for per 1 μmol/L adjusted odds ration [OR]: 0.93; 95% CI: 0.89–0.97; for per 1-SD adjusted OR: 0.89; 95% CI: 0.83–0.96) and currently diagnosed TIA or stroke (for per 1 μmol/L adjusted OR: 0.91; 95% CI: 0.87–0.96; for per 1-SD adjusted OR: 0.84; 95% CI: 0.80–0.91) after controlling the lifestyle factors and age-related confounders. The significance of these associations was maintained after a sensitivity analysis and involving “ever chronic respiratory diseases” as a covariate. Moreover, the stratified analyses suggested that the inverse associations could be affected by overweight [body mass index (BMI) ≥ 28, kg/m2], hypertension, and diabetes.Conclusions: A significant inverse association between blood retinol and the risk of TIA or stroke was found. This inverse association did not change even after adjustment for many potential confounders. Moreover, the potential protective effect of retinol on TIA/stroke could be blunted by overweight [BMI ≥ 28, kg/m2], hypertension, and diabetes.
Fasting Plasma Glucose Mediates the Prospective Effect of Maternal Metal Level on Birth Outcomes: A Retrospective and Longitudinal Population-Based Cohort Study
Authors: Zhou Zixing , Yu Dandan , Chen Gengdong , Li Pengsheng , Wang Lijuan , Yang Jie , Rao Jiaming , Lin Dongxin , Fan Dazhi , Wang Haiyan , Gou Xiaoyan , Guo Xiaoling , Suo Dongmei , Huang Fang , Liu Zhengping 
Published: November 2021

ObjectivePreviously, we found that the presence of maternal serum metals before the 24th week of gestation prospectively increased fasting plasma glucose (FPG) at 24–28 weeks. We further explored the prospective association between levels of metals and neonatal outcomes and assessed the mediating effects of FPG on these relationships.MethodsA total of 7,644 pregnant women were included in a retrospective cohort study, and the relationships between metals [manganese (Mn), copper (Cu), lead (Pb), zinc (Zn), and magnesium (Mg)] and birth outcomes were explored. Quantile and linear regressions were performed to detect the shifts and associations between metals and neonatal size distribution focused on the 10th, 50th, and 90th percentiles. Mediation analysis was performed to assess the mediating effect of FPG on metals and birth outcomes.ResultsAfter adjustment, a 50% increase in Mn and Zn levels was related to a 0.136-cm (95% CI: 0.067–0.205) and 0.120-cm (95% CI: 0.046–0.193) increase in head circumference, respectively. Based on head circumference distribution, the magnitude of the association with Mn was smaller at the upper tail, while the magnitude of correlation with Zn was greater at the upper tail. A 50% increase in Mn and Zn levels was related to a 0.135-cm (95% CI: 0.058–0.212) and 0.095-cm (95% CI: 0.013–0.178) increase in chest circumference, respectively. The magnitude of the association with Mn increased with increasing chest circumference, while the magnitude of correlation with Zn decreased with increasing chest circumference. FPG explained 10.00% and 17.65% of the associations of Mn with head and chest circumference. A positive indirect effect of Zn associated with head circumference (0.004, 95% CI: 0.002–0.006) and chest circumference (0.005, 95% CI: 0.003–0.008) through FPG was also observed, and the estimated proportion of the mediating effect was 13.79% and 26.32%, respectively.ConclusionMaternal serum Mn and Zn levels before the 24th week of gestation may prospectively increase the circumference of the neonatal head and chest. FPG at 24–28 weeks had positive mediating effects on these relationships. Further research is needed to identify a balance between maternal blood glucose and birth size.
Distinct Prognostic Role of Serum Uric Acid Levels for Predicting All-Cause Mortality Among Chinese Adults Aged 45~75 Years With and Without Diabetes
Authors: Zhu Bowen , Zhang Jian , Song Nana , Shi Yiqin , Fang Yi , Ding Xiaoqiang , Li Yang 
Published: November 2021

IntroductionThe current study sought to explore the effect of baseline serum uric acid (SUA) on the risk of all-cause mortality among Chinese adults aged 45~75 years and to determine its interaction relationship with diabetes.MethodsThe study was designed as a community-based cohort of 4467 adults aged between 45~75 years included in a 6-years follow-up period from 2009 to 2015 years by the China Health and Nutrition Survey (CHNS). Baseline SUA levels were grouped into quartiles and its association on all-cause mortality was explored using multivariate Cox proportional hazards models. Stratified analyses were performed to explore the associations of SUA quartiles with all-cause mortality among diabetic and non-diabetic individuals.ResultsA total of 141 deaths (5.3 per 1000 person-years) were recorded During a follow-up of 26431 person-years. Out of the 141 deaths, 28 deaths (10.1 per 1000 person-years) were reported in the diabetic groups and 113 deaths (4.8 per 1000 person-years) were recorded in the non-diabetic group. An increased risk of all-cause mortality was observed for participants in the first and fourth quartiles compared with the second SUA quartile, (Q1 SUA: aHR=2.1, 95% CI 1.1~4.1; Q4 SUA: aHR=2.1, 95% CI 1.1~4.0). Stratification of participants by diabetes status showed a U-shaped association for non-diabetic individuals. Whereas, declined eGFR, rather than SUA, was an independent risk factor for all-cause mortality in diabetic individuals (aHR=0.7, 95% CI 0.6~1.0).ConclusionOur study proved that the prognostic role of SUA for predicting all-cause death might be regulated by diabetes. Both low and high SUA levels were associated with increased mortality, supporting a U-shaped association only in non-diabetic individuals. Whereas, renal dysfunction rather than SUA was an independent risk factor for all-cause mortality. Further studies should be conducted to determine the SUA levels at which intervention should be conducted and explore target follow-up strategies to prevent progression leading to poor prognosis.
Trait-specific Selection Signature Detection Reveals Novel Loci of Meat Quality in Large White Pigs
Authors: Shen Yu , Wang Haiyan , Xie Jiahao , Wang Zixuan , Ma Yunlong 
Published: November 2021

In past decades, meat quality traits have been shaped by human-driven selection in the process of genetic improvement programs. Exploring the potential genetic basis of artificial selection and mapping functional candidate genes for economic traits are of great significance in genetic improvement of pigs. In this study, we focus on investigating the genetic basis of five meat quality traits, including intramuscular fat content (IMF), drip loss, water binding capacity, pH at 45 min (pH45min), and ultimate pH (pH24h). Through making phenotypic gradient differential population pairs, Wright’s fixation index (FST) and the cross-population extended haplotype homozogysity (XPEHH) were applied to detect selection signatures for these five traits. Finally, a total of 427 and 307 trait-specific selection signatures were revealed by FST and XPEHH, respectively. Further bioinformatics analysis indicates that some genes, such as USF1, NDUFS2, PIGM, IGSF8, CASQ1, and ACBD6, overlapping with the trait-specific selection signatures are responsible for the phenotypes including fat metabolism and muscle development. Among them, a series of promising trait-specific selection signatures that were detected in the high IMF subpopulation are located in the region of 93544042-95179724bp on SSC4, and the genes harboring in this region are all related to lipids and muscle development. Overall, these candidate genes of meat quality traits identified in this analysis may provide some fundamental information for further exploring the genetic basis of this complex trait.