bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mining crowdsourced trajectory and geo‐tagged data for spatial‐semantic road map construction
Authors: Huang Jincai , Zhang Yunfei , Deng Min , He Zhengbing 
Published: December 2021

AbstractThe road map is a fundamental part of a spatial data infrastructure (SDI), and is widely applied in navigation, smart transportation, and mobile location services. Recently, with the ubiquity of positioning devices, crowdsourced trajectories have become a significant data resource for road map construction and updating. However, existing trajectory‐based methods mainly place emphasis on extracting road geometry features and may ignore continuous updating of road semantic information. Hence, we propose a divide‐and‐conquer method to construct a spatial‐semantic road map by incorporating multiple data sources (e.g., crowdsourced trajectories and geo‐tagged data). The proposed method divides road map construction into two sub‐tasks, road structure reconstruction and road attributes inference. The road structure reconstruction process starts to partition raw trajectory data into different cliques of roadways and road intersections, and then extracts various targeted road structures by analyzing the turning modes in different trajectory cliques. The road attributes inference process aims to infer three pieces of crucial semantic information about road speeds, turning rules, and road names from crowdsourced trajectories and geo‐tagged data. The case studies in Wuhan were examined to illustrate that the proposed method can construct a routable road map with enhanced geometric structures and rich semantic information, providing a beneficial data solution for car navigation and SDI update.
“Let Me Double‐Check That”: A Challenge forConciliationism
Authors: Anaya Alfonso 
Published: December 2021

AbstractDouble‐checking one's reasoning is a perfectly normal way of responding to a disagreement between peers. I argue that conciliationist approaches lack the resources to accommodate this phenomenon adequately. On the one hand, conciliationists cannot claim that double‐checking is a rationally impermissible response to disagreement because a compelling case for its permissibility appeals to arguments analogous to those often used by conciliationist in favour of their own view. On the other, they lack the resources to accommodate double‐checking as a rationally permissible response to disagreement. To show this, I draw a distinction betweenstrongandmoderateversions ofconciliationism. Thestrongversion accepts, whereas the moderate version rejects, that the conciliatory obligation exhausts the rational requirements engendered by disagreements. Strong conciliationists cannot explain the motivation for someone to double‐check if they have followed the conciliationists advice.Moderateconciliationists who try to make space for double‐checking are forced to concede that disputants can respond rationally to disagreementwithoutlowering their confidence in the disputed belief.
Human pegivirus type 1 infection in kidney transplant recipients: Replication kinetics and clinical correlates
Authors: Fernández‐Ruiz Mario , Forque Lorena , Albert Eliseo , Redondo Natalia , Giménez Estela , López‐Medrano Francisco , González Esther , Polanco Natalia , Ruiz‐Merlo Tamara , Parra Patricia , San Juan Rafael , Andrés Amado , Aguado José María , Navarro David 
Published: December 2021

AbstractBackgroundIncreasing evidence suggests that infection with the nonpathogenic human pegivirus type 1 (HPgV‐1) exerts a clinical benefit in human immunodeficiency virus (HIV) patients, which could be attributable to immunomodulatory effects. Whether this impact can be extrapolated to kidney transplantation (KT) remains largely unknown.MethodsWe measured plasma HPgV‐1 RNA by real‐time polymerase chain reaction targeting the 5′ untranslated region at various points (pretransplantation, day 7, months 1, 3, 6, and 12) in 199 KT recipients. Study outcomes included posttransplant serious infection, immunosuppression‐related adverse event (opportunistic infection and/or de novo cancer), and acute graft rejection.ResultsHPgV‐1 infection was demonstrated in 52 (26.1%) patients, with rates increasing from 14.7% at baseline to 19.1% by month 12 (p‐value = .071). De novo infection occurred in 13.8% of patients with no detectable HPgV‐1 RNA before transplantation. Double‐organ (liver–kidney or kidney–pancreas) transplantation (odds ratio [OR]: 5.62; 95% confidence interval [CI]: 1.52–20.82) and donation after brain death (OR: 2.21; 95% CI: 1.00–4.88) were associated with posttransplant HPgV‐1 infection, whereas pretransplant hypertension was protective (OR: 0.23; 95% CI: 0.09–0.55). There were no significant differences in the incidence of study outcomes according to HPgV‐1 status. Plasma HPgV‐1 RNA levels at different points did not significantly differ between patients that subsequently developed outcomes and those remaining free from these events. No correlation between HPgV‐1 RNA and immune parameters or torque teno virus DNA load was observed either.ConclusionUnlike patients living with HIV, HPgV‐1 infection does not seem to influence patient or graft outcomes after KT.
SPIRITUAL ANIMALS: SENSE‐MAKING, SELF‐TRANSCENDENCE, AND LIBERAL NATURALISM
Authors: MacKenzie Matthew 
Published: December 2021

AbstractOwen Flanagan has advocated for an interdisciplinary, cross‐cultural inquiry into the nature and optimal conditions of human flourishing that he aptly terms eudaimonics. For Flanagan flourishing is multifaceted, involving biological, psychological, and social dimensions. In this article, I will explore the spiritual dimension of human flourishing from a liberal naturalist perspective. My first core claim is that, at the root of human experience, there are capacities for sense‐making and self‐transcendence. These capacities allow us, indeed drive us, to create, maintain, and transform spiritual ecologies. These ecologies allow us to find meaning, value, and purpose in our individual and shared worlds—that is, to be spiritually at home. My second core claim is that this spiritual dimension is a distinct and irreducible dimension of our flourishing. The spiritual dimension centrally involves the depth and integration of our human orientation to life. In my view, we are inescapably spiritual animals and any adequate eudaimonics must take this into account.
A comparison between left ventricular ejection time measurement methods during physiological changes induced by simulated microgravity
Authors: Orter Stefan , Möstl Stefan , Bachler Martin , Hoffmann Fabian , Mayer Christopher C. , Kaniusas Eugenijus , Reisinger Michaela , Wassertheurer Siegfried , Tank Jens , Jordan Jens , Hametner Bernhard 
Published: December 2021

New Findings

What is the central question of this study?
First, we validated easy‐to‐use oscillometric left ventricular ejection time (LVET) against echocardiographic LVET. Second, we investigated progression of left ventricular ejection time index (LVETI), pre‐ejection period index (PEPI), total electromechanical systole index (QS2I) and PEP/LVET ratio during 60 days of head‐down tilt (HDT).

What is the main finding and its importance?
The LVETosci and LVETecho showed good agreement in effect direction. Hence, LVETosci might be useful to evaluate cardiovascular responses during space flight. Moreover, the approach might be useful for individual follow‐up of patients with altered ejection times. Furthermore, significant effects of 60 days of HDT were captured by measurements of LVETI, PEPI, QS2I and PEP/LVET ratio.

AbstractSystolic time intervals that are easy to detect might be used as parameters reflecting cardiovascular deconditioning. We compared left ventricular ejection time (LVET) measured via ultrasound Doppler on the left ventricular outflow tract with oscillometrically measured LVET, measured at the brachialis. Furthermore, we assessed the progression of the left ventricular ejection time index (LVETI), the pre‐ejection period index (PEPI), the Weissler index (PEP/LVET) and the total electromechanical systole index (QS2I) during prolonged strict head‐down tilt (HDT) bed rest, including 16 male and eight female subjects. Simultaneous oscillometric and echocardiographic LVET measurements showed significant correlation (r = 0.53 with P = 0.0084 before bed rest and r = 0.73 with P < 0.05 on the last day of bed rest). The shortening of LVET during HDT bed rest measured with both approaches was highly concordant in their effect direction, with a concordance rate of 0.96. Our results also demonstrated a significant decrease of LVETI (P < 0.0001) and QS2I (P = 0.0992) and a prolongation of PEPI (P = 0.0049) and PEP/LVET (P = 0.0003) during HDT bed rest over 60 days. Four days after bed rest, LVETI recovered completely to its baseline value. Owing to the relationship between shortening of LVETI and heart failure progression, the easy‐to‐use oscillometric method might not only be a useful way to evaluate the cardiovascular system during space flights, but could also be of high value in a clinical setting.
Social isolation is a direct determinant of decreased home‐cage activity in mice: A within‐subjects study using a body‐implantable actimeter
Authors: Funabashi Daisuke , Wakiyama Yusuke , Muto Naoya , Kita Ichiro , Nishijima Takeshi 
Published: December 2021

New Findings

What is the central question of this study?
It is generally recognized that social isolation is associated with physical inactivity, but is social isolation a direct determinant of decreased physical activity?

What is the main finding and its importance?
We conducted a within‐subjects experiment with the aid of a body‐implantable actimeter. Our results clearly demonstrated that social isolation decreased home‐cage activity in mice. This might have resulted from increased immobility and decreased vigorous activity, suggesting that avoidance of social isolation is important to prevention of physical inactivity.

AbstractAn inactive lifestyle can have a negative impact on physiological and mental health. Social isolation is associated with physical inactivity; however, it remains uncertain whether social isolation is a direct determinant of decreased physical activity. Hence, we assessed whether social isolation decreases home‐cage activity using a within‐subjects design and examined the effects of social isolation on hippocampal neurogenesis in mice. This study used a body‐implantable actimeter called nanotag, which enabled us to measure home‐cage activity despite housing the mice in groups. Initially, we examined the influence of the intraperitoneal implantation of nanotag on home‐cage activity. Although nanotag implantation decreased home‐cage activity temporarily, at 7 days postimplantation the activity recovered to the same level as that of control (non‐implanted) mice, suggesting that implantation of nanotag does not have a negative influence on home‐cage activity if mice undergo a 1 week recovery period after implantation. In the main experiment, after the 1 week baseline measurement performed with mice in group housing, the mice were placed in a group or in isolation. Home‐cage activity was measured for an additional 4 weeks. Home‐cage activity in isolated mice during the dark period decreased by 26% from pre‐intervention to the last week of intervention. Furthermore, the reduction in the number of 5 min epochs during which the activity count exceeded 301 (an index of vigorous activity) was significantly larger for isolated mice. Contrary to expectations, social isolation did not impair hippocampal neurogenesis. Our results demonstrate that social isolation is a direct determinant of decreased physical activity, possibly because of reduced vigorous physical activity.
Thermosolutal LTNE Porous Mixed Convection Under the Influence of the Soret Effect
Authors: Hemanth Kumar C. , Shankar B. M. , Shivakumara I. S. 
Published: December 2021

AbstractThe onset of thermosolutal convection in a fluid-saturated porous medium in the presence of a horizontal pressure gradient and the Soret effect under the two-temperature model of local thermal nonequilibrium (LTNE) is investigated. The Darcy model with the time-dependent velocity term in the momentum equation is employed together with the Oberbeck–Boussinesq approximation. The eighth-order eigenvalue differential equation obtained by employing linear stability analysis is solved using Galerkin's method of weighted residuals (GMWR) and also analytically. The onset of convection instills through oscillatory rather than stationary mode, and the critical stability parameters for the same are determined. The horizontal pressure gradient reinforces together with the solute concentration gradient and the scaled interphase heat transfer coefficient in evidencing mixed behavior on the criterion for the onset of oscillatory convection. Besides, the similarities and differences between the results of thermal and thermosolutal LTNE porous mixed convection are discerned.
Calcite twinning strains associated with Laramide uplifts, Wyoming Province
Authors: Craddock John P. , Malone David H. , Konstantinou* Alexandros , Spruell John , Porter Ryan 
Published: December 2021

ABSTRACT
We report the results of 167 calcite twinning strain analyses (131 limestones and 36 calcite veins, n = 7368 twin measurements) from the Teton–Gros Ventre (west; n = 21), Wind River (n = 43), Beartooth (n = 32), Bighorn (n = 32), and Black Hills (east; n = 11) Laramide uplifts. Country rock limestones record only a layer-parallel shortening (LPS) strain fabric in many orientations across the region. Synorogenic veins record both vein-parallel shortening (VPS) and vein-normal shortening (VNS) fabrics in many orientations. Twinning strain overprints were not observed in the limestone or vein samples in the supracrustal sedimentary veneer (i.e., drape folds), thereby suggesting that the deformation and uplift of Archean crystalline rocks that form Laramide structures were dominated by offset on faults in the Archean crystalline basement and associated shortening in the midcrust. The twinning strains in the pre-Sevier Jurassic Sundance Formation, in the frontal Prospect thrust of the Sevier belt, and in the distal (eastern) foreland preserve an LPS oriented approximately E-W. This LPS fabric is rotated in unique orientations in Laramide uplifts, suggesting that all but the Bighorn Mountains were uplifted by oblique-slip faults. Detailed field and twinning strain studies of drape folds identified second-order complexities, including: layer-parallel slip through the fold axis (Clarks Fork anticline), attenuation of the sedimentary section and fold axis rotation (Rattlesnake Mountain), rotation of the fold axis and LPS fabric (Derby Dome), and vertical rotations of the LPS fabric about a horizontal axis with 35% attenuation of the sedimentary section (eastern Bighorns). Regional cross sections (E-W) across the Laramide province have an excess of sedimentary veneer rocks that balance with displacement on a detachment at 30 km depth and perhaps along the Moho discontinuity at 40 km depth. Crustal volumes in the Wyoming Province balance when deformation in the western hinterland is included.
Constraints on antisymmetric tensor fields from Bhabha scattering
Authors: Tiwary Siddharth , Dick Rainer 
Published: December 2021

AbstractAntisymmetric tensor fields are a compelling prediction of string theory. This makes them an interesting target for particle physics because antisymmetric tensors may couple to electromagnetic dipole moments, thus opening a possible discovery opportunity for string theory. The strongest constraints on electromagnetic dipole couplings would arise from couplings to electrons, where these couplings would contribute to Møller and Bhabha scattering. Previous measurements of Bhabha scattering constrain the couplings to $${\tilde{M}}_e m_C>7.1\times 10^4\,{\mathrm {GeV}}^2$$

M
~

e

m
C

>
7.1
×

10
4

GeV

2

, where $$m_C$$

m
C

is the mass of the antisymmetric tensor field and $${\tilde{M}}_e$$

M
~

e

is an effective mass scale appearing in the electromagnetic dipole coupling.
Higgs and top physics reconstruction challenges and opportunities at FCC-ee
Authors: Azzi Patrizia , Gouskos Loukas , Selvaggi Michele , Simon Frank 
Published: December 2021

AbstractThe Higgs bosons and the top quark decay into rich and diverse final states, containing both light and heavy quarks, gluons, photons as well as W and Z bosons. This article reviews the challenges involved in reconstructing Higgs and top events at the FCC-ee and identifies the areas where novel developments are needed. The precise identification and reconstruction of these final states at the FCC-ee rely on the capability of the detector to provide excellent flavour tagging, jet energy and angular resolution, and global kinematic event reconstruction. Excellent flavour tagging performance requires low-material vertex and tracking detectors, and advanced machine learning techniques as successfully employed in LHC experiments. In addition, the Z pole run will provide abundant samples of heavy flavour partons that can be used for calibration of the tagging algorithms. For the reconstruction of jets, leptons, and missing energy, particle-flow algorithms are crucial to explore the full potential of the highly granular tracking and calorimeter systems, and give access to excellent energy–momentum resolution and precise identification of heavy bosons in their hadronic decays. This enables, among many other key elements, the reconstruction of Higgsstrahlung processes with leptonically and hadronically decaying Z bosons, and an almost background-free identification of top quark pair events. Exploiting the full available kinematic constraints together with exclusive jet clustering algorithms will allow for the optimisation of global event reconstruction with kinematic fitting techniques.
Systemic Governance of Mountains, Rivers, Forests, Farmlands, Lakes and Grasslands: Theoretical Framework and Approaches
Authors: ZHENG Yan , ZHUANG Guiyang 
Published: December 2021

The life community of mountains, rivers, forests, farmlands, lakes and grasslands (MRFFLG) and its systemic governance are key components to build ecological civilization in China. It comprises diverse connotations in value, scientific and economic dimensions. Epistemologically, it comes from the Chinese traditional philosophy of harmonious coexistence of heaven, earth and man, and conforms to the Western ecological ethics, complex system science and environmental value theory. Methodologically, as a complex socio-ecological system in which man and nature interact and coexist, the life community of the MRFFLG should be governed coordinately from both narrow and broad views. At the policy level, from the perspectives of narrow synergy among ecological subsystems and broad synergy among the complex socio-ecological system, this paper evaluates the performance indicators of 16 pilot projects of the MRFFLG, and points out that the design of most pilot projects well reflects the narrow synergy of multiple ecological elements, but is short of attention to the broad synergy of green development and ecological civilization. There are two practical ways to promote the systemic governance of the MRFFLG. First, it needs to focus on the coordinated governance of watershed and ecological environment restoration against the background of global climate and environmental change. The goal is to restore and improve the service functions of ecological subsystems and enhance their climate adaptability. Second, in the context of new urbanization and green development transition, it requires a collaborative planning focusing on natural capital and green infrastructure investment, which is aimed at cultivating ecological dividends and realizing ecological economy.
Electroacupuncture Alleviates Hyperalgesia by Regulating CB1 Receptor of Spinal Cord in Incisional Neck Pain Rats
Authors: Wang Junying , Zhang Jinling , Gao Yonghui , Chen Yu , Duanmu Chenglin , Liu Junling 
Published: December 2021

Acupuncture therapy is effective in relieving postoperative pain of neck surgery, but its underlying mechanisms remain largely unknown. This study, in the incisional neck pain rat model, was designed to explore whether the endocannabinoid receptor 1 (CB1) in the cervical spinal cord is involved in the analgesic effect of electroacupuncture (EA) or not.The incisional neck pain model was established by making a longitudinal incision and applied EA treatment of Futu (LI18), Hegu-Neiguan (LI4-PC6), or Zusanli-Yanglingquan (ST36-GB34) for pain relief. The results showed that EA LI18 and EA LI4-PC6 effectively relieve allodynia caused by neck incision, which was obviously better than EA ST34-GB34 (

P

< 0.05). After EA, the expression levels of CB1 mRNA at 4h in the EALI18 group, and 24 and 48h in both EALI18 and EALI4-PC6 groups, and those of CB1 protein at 4, 24, and 48h in the EALI18 group, and the immunoactivity of CB1 in both EALI18 and EALI4-PC6 groups at 4h were significantly upregulated in contrast to those of the model group (

P

< 0.05). EA of either acupoint group had no effect on the expression of CB2 protein (

P

> 0.05). Moreover, the antinociceptive effect of EA was reversed by AM251 (CB1 antagonist). Immunofluorescence dual staining showed that CB1 expressed in astrocytes in the superficial layer (laminae I and II) of dorsal horns of the cervical spinal cord. Therefore, the findings of this study revealed that upregulation of CB1 expression in the cervical spinal cord contributes to the analgesic effect of EA in incisional neck pain rats. The CB1 receptor expresses on astrocytes.
Desafíos de la educación en odontología
Authors: Isbej Esposito Lorena , Cantarutti Martínez Cynthia , Carrasco-Labra Alonso , Hassi Thumala José , García-Huidobro Kirberg Rosario , Ortuño Borroto Duniel , Oyarzo Paredes Natacha , Naranjo Camilla Claudia , Véliz Paiva Claudia 
Published: December 2021

Introducción: los procesos de enseñanza aprendizaje en odontología deben adaptarse permanentemente a los cambios sociales, demográficos, científicos y tecnológicos, con el fin de formar profesionales con un perfil de egreso basado en conocimientos, habilidades y actitudes integrales, conectados con la realidad y necesidades de la sociedad, que impacten positivamente en el sistema de salud. El propósito de esta revisión narrativa fue analizar los principales desafíos de la educación en odontología reportados en la literatura y proponer acciones concretas para abordarlos. Métodos: a través de un método de consenso, un panel de nueve expertos seleccionó las principales áreas donde se presentan estos desafíos, para luego realizar una búsqueda de información científica en inglés y español, consultando las bases de datos MEDLINE vía PubMed, ERIC (EBSCO), Scopus, SciELO y Google Scholar. Resultados: los cuatro desafíos para la educación en odontología analizados fueron: responsabilidad social de la educación, perfil de egreso de en diferentes contextos, metodologías de enseñanza aprendizaje y sistemas de evaluación, procesos de titulación y certificación. Conclusiones: las acciones que sustentan los principales cambios requeridos a nivel nacional e internacional en la educación en odontología necesitan el apoyo transversal de organizaciones gubernamentales, científicas, sociales y de las propias instituciones de educación superior, a través de un trabajo colaborativo. Este camino es vital para lograr la formación de cirujanos dentistas que serán reales agentes de cambio, preparados integralmente para insertarse en un sistema que garantice la calidad, seguridad, efectividad y equidad en salud bucal.