bluuebunny/crossref_metadata_2025_split huggingface dataset:
Disrupted Regional Homogeneity in Major Depressive Disorder With Gastrointestinal Symptoms at Rest
Authors: Yan Meiqi , Chen Jindong , Liu Feng , Li Huabing , Huang Renzhi , Tang Yanqing , Zhao Jingping , Guo Wenbin 
Published: May 2021

Background: Gastrointestinal (GI) symptoms are prominent in patients with major depressive disorder (MDD). Previous studies have reported brain structural and functional changes in both MDD and digestive system diseases but it remains unclear whether MDD patients with GI symptoms have brain imaging changes.Methods: We recruited 35 MDD patients with GI symptoms, 17 MDD patients without GI symptoms and 28 age-, gender-, and education-matched healthy controls. All participants were scanned by resting-state functional magnetic resonance imaging (fMRI). Imaging data were analyzed with regional homogeneity (ReHo).Results: The GI group showed higher total HRSD-17 scores, anxiety/somatization, weight loss, and sleep disturbance scores compared to the non-GI group. We found increased ReHo in the right inferior parietal gyrus (IPL), bilateral supplementary motor area (SMA), bilateral cerebellum Crus II, left inferior frontal gyrus (IFG), and bilateral superior medial frontal cortex (SMFC) and decreased ReHo in the right posterior cingulate cortex (PCC), bilateral cuneus, and left middle occipital gyrus (MOG) in patients with GI symptoms relative to the HCs. The GI group showed higher ReHo values in the bilateral precuneus than the non-GI group.Conclusion: MDD patients with GI symptoms showed a greater severity of symptoms than MDD patients without GI symptoms, particularly in terms of anxiety/somatization, weight loss, and sleep disturbances. Increased activity in the default-mode network might be associated with GI symptoms in MDD patients.
Insomnia Disorder in Adult Attention-Deficit/Hyperactivity Disorder Patients: Clinical, Comorbidity, and Treatment Correlates
Authors: Fadeuilhe Christian , Daigre Constanza , Richarte Vanesa , Grau-López Lara , Palma-Álvarez Raul F. , Corrales Montse , Ramos-Quiroga Josep A. 
Published: May 2021

Introduction: Several investigations have been performed on insomnia symptoms in adult attention-deficit/hyperactivity disorder (ADHD). However, the relationship between insomnia disorder and adult ADHD has been neglected in research. The main objective of the current study is to analyze the differences between adult ADHD patients with and without insomnia disorder, in terms of ADHD clinical severity, medical and psychiatric comorbidity, psychopharmacological treatment, and quality of life.Material and Methods: Two hundred and fifty-two adult patients with ADHD (mean age 37.60 ± 13.22 years; ADHD presentations—combined: 56.7%, inattentive: 39.7%, hyperactive/impulsive: 3.6%) were evaluated with an exhaustive clinical and psychological evaluation protocol including semistructured interviews (for comorbidities and ADHD assessment) and symptom rating scales for ADHD. The diagnosis of ADHD and insomnia disorder was made according to DSM-5 criteria. Furthermore, the Pittsburgh Sleep Quality Index, Insomnia Severity Index, and Epworth Sleepiness Scale were administered.Results: Insomnia disorder was found in 44.4% of adult ADHD patients and was more common in combined presentation (64.3%) and in patients with more ADHD severity. Comorbidities (both medical and psychiatric), especially mood disorders (42%), anxiety disorder (26.8%), personality disorder (39.3%), and any substance use disorder (11.6%), were associated with a higher insomnia disorder prevalence. ADHD stimulant treatment was related to lower insomnia disorder compared to patients without medication, as well as ADHD stable treatment. Additionally, worse health-related quality of life was associated with insomnia disorder.Conclusion: Insomnia disorder is highly prevalent in adult ADHD and is related to higher ADHD severity and more psychiatric and medical comorbidities. Some stimulants and stable pharmacological ADHD treatment are associated with better outcomes of insomnia disorder.
In Chronic Spontaneous Urticaria, Comorbid Depression Linked to Higher Disease Activity, and Substance P Levels
Authors: Memet Bachar , Vurgun Eren , Barlas Fatma , Metz Martin , Maurer Marcus , Kocatürk Emek 
Published: May 2021

Background:Patients with chronic spontaneous urticaria often exhibit psychiatric comorbidities including depression that contribute to the impairment of their quality of life. How CSU and depression are linked isn't well-understood. Substance P has been shown to be increased in patients with CSU and is held to contribute to the pathogenesis of depression.Methods:We measured disease activity in 30 CSU patients without depression and 30 CSU patients with depression by using the urticaria activity score. The severity of depression was assessed with the Beck Depression Inventory. We measured SP levels in these patients as well as in 30 healthy control subjects. In patients with comorbid depression, we correlated SP levels with CSU disease activity and the severity of depression.Results:In CSU patients, disease activity and the severity of depression were positively linked. UAS7 values were higher in CSU patients with comorbid depression as compared to those without (p&lt; 0.05). SP levels were higher in CSU patients with depression than in those without (p&lt; 0.001), but was similar in all CSU patients compared to healthy controls. SP levels weren't correlated with UAS7 values in CSU patients with depression, whereas they were weakly but significantly correlated with BDI scores (p&lt; 0.05).Conclusion:Our results suggest that, in CSU patients with comorbid depression, CSU disease activity affects the severity of depression. CSU patients with high disease activity should be explored for comorbid depression.
Association of Prenatal Ambient Air Pollution Exposure With Placental Mitochondrial DNA Copy Number, Telomere Length and Preeclampsia
Authors: Mandakh Yumjirmaa , Oudin Anna , Erlandsson Lena , Isaxon Christina , Hansson Stefan R. , Broberg Karin , Malmqvist Ebba 
Published: May 2021

Background: Studies have shown that ambient air pollution is linked to preeclampsia (PE), possibly via generation of oxidative stress in the placenta. Telomere length and mitochondrial DNA copy number (mtDNAcn) are sensitive to oxidative stress damage.Objective: To study the association between prenatal exposure to ambient nitrogen oxides (NOx, a marker for traffic-related air pollution), and PE, as well as potential mediation effects by placental telomere length and mtDNAcn.Methods: This is a cross-sectional study of 42 preeclamptic and 95 arbitrarily selected normotensive pregnant women with gestational ambient NOx exposure assessment in southern Scania, Sweden. Hourly concentrations of NOx were estimated at the residential addresses by a Gaussian-plume dispersion model with 100 × 100 m spatial resolutions and aggregated into trimester-specific mean concentrations. Placental relative mtDNAcn and telomere length were measured using qPCR. Linear and logistic regression models were used to investigate associations, adjusted for perinatal and seasonal characteristics.Results: Exposure was categorized into low and high exposures by median cut-offs during first [11.9 μg/m3; interquartile range (IQR) 7.9, 17.9], second (11.6 μg/m3; IQR: 7.1, 21.1), third trimesters (11.9 μg/m3; IQR: 7.7, 19.5) and entire pregnancy (12.0 μg/m3; IQR: 7.6, 20.1). Increased risk of PE was found for high prenatal NOx exposure during the first trimester (OR 4.0; 95% CI: 1.4, 11.1; p = 0.008), and entire pregnancy (OR 3.7; 95% CI: 1.3, 10.4; p = 0.012). High exposed group during the first trimester had lower placental relative mtDNAcn compared with low exposed group (−0.20; 95% CI: −0.36, −0.04; p = 0.01). Changes in relative mtDNAcn did not mediate the association between prenatal NOx exposure and PE. No statistically significant association was found between placental relative telomere length, prenatal NOx exposure and PE.Conclusion: In this region with relatively low levels of air pollution, ambient NOx exposure during the first trimester was associated with reduced placental relative mtDNAcn and an increased risk of PE. However, we did not find any evidence that mtDNAcn or TL mediated the association between air pollution and PE. Future research should further investigate the role of mtDNAcn for pregnancy complications in relation to exposure to ambient air pollution during pregnancy.
Tumor Inhibitory Effect of Long Non-coding RNA LOC100505817 on Gastric Cancer
Authors: Zheng Lei , Kang Liying , Cheng Yan , Cao Junli , Liu Lijie , Xu Hongmei , Gao Liming 
Published: May 2021

Gastric cancer (GC) is one of the major malignancies worldwide. Emerging evidence has revealed the potential involvement of long noncoding RNA (lncRNA) in human genetic disorders and cancer, but the role of LOC100505817 remains unknown. Thus, in this study, we isolated tissues from GC patients to characterize the functional importance of LOC100505817 in GC tumorigenesis. We also proposed a hypothesis that the regulation of Wnt/β-catenin pathway by LOC100505817 was regulated by miR-20a-mediated WT1. After the collection of cancer tissues and adjacent tissues were obtained from GC patients, expression of LOC100505817, Wnt/β-catenin pathway- and EMT-related genes was quantified. Ectopic expression and knockdown experiments were applied in order to investigate the protective role of LOC100505817 in the progression of GC. Subsequently, cell viability, flow cytometry for apoptosis and cell cycle were detected via CCK-8, while migration and invasion were determined using scratch test and Transwell assay respectively. Then interactions among LOC100505817, miR-20a and WT1 were explored by dual luciferase reporter gene assay, RNA pull down assay and RNA binding protein immunoprecipitation (RIP) assay. The results found poor expression LOC100505817 was poorly expressed in GC cells and tissues. Overexpressed LOC100505817 resulted in the significant reduction of cell proliferation, migration and invasion as well as the expression of Wnt2b, β-catenin, CyclinD1, N-cadherin, Vimentin and snail, while increased cell apoptosis along with the expression of E-cadherin. Wnt/β-catenin pathway and EMT in GC cells were suppressed by LOC100505817 through miR-20a-inhibted WT1. In summary, our results provided evidence suggesting that LOC100505817 inhibits GC through LOC100505817-mediated inhibition of Wnt/β-catenin pathway, that leads to the overall restraining of GC cell proliferation, migration and invasion through miR-20a-reduced WT1.
Salmonella enterica Subsp. houtenae Associated with an Abscess in Young Roe Deer (Capreolus capreolus)
Authors: Trotta Adriana , Del Sambro Laura , Galgano Michela , Ciccarelli Stefano , Ottone Erika , Simone Domenico , Parisi Antonio , Buonavoglia Domenico , Corrente Marialaura 
Published: May 2021

Background: S. enterica subsp. houtenae has been rarely documented, and very limited genomic information is available. This report describes a rare case of primary extraintestinal salmonellosis in a young roe deer, associated with Salmonella enterica subsp. houtenae. Methods: A traditional cultural-based analysis was carried out from the contents of a neck abscess; biochemical identification and PCR assay were performed to isolate and identify the pathogen. Through whole-genome sequencing (WGS), multilocus sequence typing (MLST), core genome MLST (cgMLST), and the Salmonella pathogenicity islands (SPIs) survey, resistome and virulome genes were investigated to gain insight into the virulence and antimicrobial resistance of S. houtenae. Results: Biochemical identification and PCR confirmed the presence of Salmonella spp. in the swelling. The WGS analysis identified Salmonella enterica subspecies houtenae serovar 43:z4,z23:- and ST 958. The virulence study predicted a multidrug resistance pattern with resistance shown against aminoglycosides, tetracycline, beta-lactamase, fluoroquinolones, fosfomycin, nitroimidazole, aminocoumarin, and peptide. Fifty-three antibiotic-resistant genes were identified. No plasmids were detected. Conclusion: This study demonstrates the importance of continuous surveillance of pathogenic salmonellae. Biomolecular analyses combined with epidemiological data can provide important information about poorly described Salmonella strains and can help to improve animal welfare.
FACTORS PREDICTING INDIVIDUAL HEALTH BEHAVIORS DURING COVID-19 PANDEMIC
Authors: Van Chan Huynh , Mai Lan Nguyen Thi , Dung Vu , Minh Thuan Le , Thu Trang Vu , Thi Thanh Nga Nguyen , Nhan Ai Nguyen , Thuy Hao Ngo , Thi Dieu Linh Dao , Xuan Long Nguyen , Thanh Ha Le , Minh Nguyet Le , Xuan Hieu Ngo , Minh Long Dau , Ha Le Vu 
Published: May 2021

Background: Covid - 19 is a global pandemic, affecting all areas of social life in every country. In the current conditions of the Covid-19 pandemic, individual health behaviors are of primary importance. Each citizen consciously implements their health behaviors not only to prevent them from being infected but also to help the country's prevention of Covid-19 effective. The study of factors predicting people’s health behaviors in the community will help managers come up with appropriate measures to improve public health and to quickly repel the pandemic.
Objectives: The research analyzes factors predicting personal health behaviors during the Covid-19 pandemic in Vietnam, including: pandemic awareness, self-assessment of the possibility of becoming infected, fear of disease, quality of life, and mental health (anxiety).
Methods: This was a cross-sectional quantitative study. Data were collected from a convenient sample of 572 people in Vietnam (118 males, 451 females; M age =27.0 (sd = 10.0) ) by a means of an online questionnaire survey. The questionnaire was constructed based on the YouGov Behavior Change questionnaire; the Fear of Coronavirus-19 Scale (FCV-19), WHOQOL-BREF, the Moral Foundation Questionnaire, and Knowledge of Covid-19. This study performed multivariate regression analysis to explore effects of moral, quality of life, knowledge and fear of Coronavirus-19 on health behaviors of participants.
Result: The result showed that fear and sex factors explain 4% (R2-adj = 4%) of health behavior change in the Covid-19 pandemic. In addition, there is a signìicant relationship between health behaviors and fear, age, gender, and occupation.
Conclusion: People's health behaviors are particularly concerned during the Covid-19 pandemic. Community healthcare activities for the people should be tailored to suit different population groups such as gender, age or emotional experiences. More in-depth studies are needed to find out the causes of these differences, thereby proposing practical solutions to help people practice more effective health behaviors, contributing to preventing and combating the outbreak.
Reconstruction methods during laparoscopic gastrectomy
Authors: Amilcare Parisi  , Chang-Ming Huang  
Published: May 2021

Gastric surgery is one of the most relevant fi elds of development for minimally invasive technologies. Laparoscopy is now widespread, and several studies have demonstrated its feasibility and safety even in some advanced oncological procedures. Robotic surgery has several intrinsic advantages that theoretically can improve an extensive lymphadenectomy or the reconstruction phase. Much remains to be addressed in this field and further studies are necessary to offer the patient the best possible approach based on his characteristics and the stage of his disease. The present report off ers an overview on robotics and its role in gastric surgery.
COMPARATIVE ANALYSIS OF EXISTING METHODS FOR DEVELOPING CORRESPONDENCE MATRICES
Authors: Lebedeva Ol'ga 
Published: May 2021

The study is aimed at comparing the methods of restoring correspondence matri ces, the traditional transport school and modern mobile technologies. Traditionally, correspondence
matrices are restored by interviewing vehicle drivers and applying gravity models (to extrapolate and
fill in unobserved movements), then matrix estimation methods are used to calculate traffic flows.
Each of these approaches has a number of advantages and disadvantages, but there is no evidence
to assess the quality of the data obtained.
INVESTIGATION OF THE THERMAL CONDUCTIVITY OF AUTOCLAVED AER ATED CONCRETE
Authors: Ryabkov Maksim , Baranova Al'bina , Skulin Aleksandr , Kocyr' Alina 
Published: May 2021

The results of measuring the thermal conductivity coefficients of autoclaved aerated
concrete grades D450 and D600 in the dry, water-saturated and frozen state are presented.
MODERNIZATION THE STAGE OF METHYLAMINES RECTIFICATION IN JSC «ANHK»
Authors: Shvalev Egor , Kuzora Igor' , Dubrovskiy Dmitriy , Semenov Ivan 
Published: May 2021

The article describes the experience of JSC «ANHK» in modernizing the most en ergy-intensive stage of methylamine production in replacing the outdated grooved plates. The low
productivity of the installation and the large diameters of the columns for the production of methyla mines forced to take a non-standard approach to the selection and replacement of internal contact
devices. The modernization made it possible to obtain a significant economic effect several times
greater than the costs of developing and implementing the project
ARES.*
V. No Evidence For Molecular Absorption in the HST WFC3 Spectrum of GJ 1132 b
Authors: Mugnai Lorenzo V. , Modirrousta-Galian Darius , Edwards Billy , Changeat Quentin , Bouwman Jeroen , Morello Giuseppe , Al-Refaie Ahmed , Baeyens Robin , Bieger Michelle Fabienne , Blain Doriann , Gressier Amélie , Guilluy Gloria , Jaziri Yassin , Kiefer Flavien , Morvan Mario , Pluriel William , Poveda Mathilde , Skaf Nour , Whiteford Niall , Wright Sam , Yip Kai Hou , Zingales Tiziano , Charnay Benjamin , Drossart Pierre , Leconte Jérémy , Venot Olivia , Waldmann Ingo , Beaulieu Jean-Philippe 
Published: May 2021

Abstract
We present a study on the spatially scanned spectroscopic observations of the transit of GJ 1132 b, a warm (∼500 K) super-Earth (1.13 R
⊕) that was obtained with the G141 grism (1.125–1.650 μm) of the Wide Field Camera 3 (WFC3) on board the Hubble Space Telescope. We used the publicly available Iraclis pipeline to extract the planetary transmission spectra from the five visits and produced a precise transmission spectrum. We analyzed the spectrum using the TauREx3 atmospheric retrieval code, with which we show that the measurements do not contain molecular signatures in the investigated wavelength range and are best fit with a flat-line model. Our results suggest that the planet does not have a clear primordial, hydrogen-dominated atmosphere. Instead, GJ 1132 b could have a cloudy hydrogen-dominated atmosphere, have a very enriched secondary atmosphere, be airless, or have a tenuous atmosphere that has not been detected. Due to the narrow wavelength coverage of WFC3, these scenarios cannot be distinguished yet, but the James Webb Space Telescope may be capable of detecting atmospheric features, although several observations may be required to provide useful constraints.
An Exploration of Model Degeneracies with a Unified Phase Curve Retrieval Analysis: The Light and Dark Sides of WASP-43 b
Authors: Changeat Q. , Al-Refaie A. F. , Edwards B. , Waldmann I. P. , Tinetti G. 
Published: May 2021

Abstract
The analysis of exoplanetary atmospheres often relies upon the observation of transit or eclipse events. While very powerful, these snapshots provide mainly one-dimensional information on the planet structure and do not easily allow precise latitude–longitude characterizations. The phase curve technique, which consists of measuring the planet emission throughout its entire orbit, can break this limitation and provide useful two-dimensional thermal and chemical constraints on the atmosphere. As of today, however, computing performances have limited our ability to perform unified retrieval studies on the full set of observed spectra from phase curve observations at the same time. Here, we present a new phase curve model that enables fast, unified retrieval capabilities. We apply our technique to the combined phase curve data from the Hubble and Spitzer space telescopes of the hot Jupiter WASP-43 b. We tested different scenarios and discussed the dependence of our solution on different assumptions in the model. Our more comprehensive approach suggests that multiple interpretations of this data set are possible, but our more complex model is consistent with the presence of thermal inversions and a metal-rich atmosphere, contrasting with previous data analyses, although this likely depends on the Spitzer data reduction. The detailed constraints extracted here demonstrate the importance of developing and understanding advanced phase curve techniques, which we believe will unlock access to a richer picture of exoplanet atmospheres.
Le renouveau du store vénitien, reflet d’un matériau moderne
Authors: Beiglig Alice 
Published: May 2021

Cet article traite du store vénitien en aluminium, objet de second œuvre souvent discret dans la construction. Dans un contexte où, dès le début du XX e siècle, la lumière se trouve au centre de la conception architecturale, l’utilisation de ce système hybride, entre le rideau et le volet, devient la réponse évidente à l’occultation de baies de toutes tailles. Sa simplicité d’usage, sa modularité mais surtout son changement de matière, allant du bois à l’aluminium, en font un produit adapté à l’architecture moderne de l’époque. Une base de données composée de coupures publicitaires et d’exemples architecturaux dans lequel il est mis en œuvre dans les années 1950 et 1960, permet de comprendre comment ce store à lamelles a su s’imposer grâce à ces qualités innées. Utilisé en intérieur, présenté comme une solution idéale à l’ensoleillement dans le logement, en extérieur dans les bureaux où les bâtiments industriels, mais aussi intégré entre deux vitrages, dans certains bâtiments publics, sa mise en œuvre variée s’adapte à tous types et toutes échelles de programmes.