bluuebunny/crossref_metadata_2025_split huggingface dataset:
CORRELATION OF PAP SMEAR AND COLPOSCOPIC FINDING WITH DIRECTED BIOPSY TO ASSESS THE ADVANTAGE OF CONCURRENT TESTING BY CYTOLOGY AND COLPOSCOPY IN THE DETECTION OF CERVICAL NEOPLASM
Authors: Chittara Diksha Kumari , Mendiratta Suman , Gurjar Anil 
Published: November 2021

Background: Cervical cancer was the second most common cancer among women 15-44 years of age and in 2018 it was the fourth most frequent cancer and cause of cancer death among all women in the world
Methods:Women (18-65 yrs) attending Department of Obstetrics and Gynaecology, SMS Medical College, Jaipur were recruited for study. After applying inclusion and exclusion criteria written and informed consent were taken from all study participants
Results: On histopathology report we found that 10% had normal inflammation followed by 9.33% had carcinoma in situ, 8% had CIN-2, 6.67% had CIN-1, 5.67% had CIN-3 and Squamous cell carcinoma each.
Conclusion: Pap smear and colposcopy both the tests can be used to complement each other in a hospital based screening programme, where facilities for both modalities are available. Hence use of single visit approach in which cytology, colposcopy and guided biopsy all are done in single sitting, and treated accordingly in resource poor countries like ours will enable maximal utilization of scarce medical resources.
Keywords: Pap smear, CIN, Cervical cancer
A COMPARATIVE STUDY OF THE ASSOCIATION OF SERUM FERRITIN LEVEL WITH GESTATIONAL DIABETES MELLITUS IN THE DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY AT SMS MEDICAL COLLEGE & ATTACHED GROUP OF HOSPITALS, JAIPUR
Authors: Inaniya Priyanka , Meena B S , Sharma Manju , Meena Mohan Lal , Gera Rashma , Sharma Aparna 
Published: November 2021

Background: The present study aimed to study the association of Serum Ferritin level with gestational diabetes mellitus
Methods: All Pregnant Females in Gestational age of 16 to 32 weeks presenting to the Ante natal clinic of Department of Obstetrics and Gynaecology, SMS Medical College, Jaipur. Based on Oral Glucose tolerance test, study participants were divided into two groups, Pregnant female with Gestational Diabetes (GDM group) and Pregnant female without Gestational Diabetes (Controls)
Results: Mean ferritin level was significantly higher in GDM group (33.51 ng/ml)) as compared to control group (24.97 ng/ml). This difference in mean ferritin level among the two groups was found to be statistically significant (p<0.001). This indicates that higher ferritin level is significantly associated with risk of GDM.
Conclusion: Serum ferritin in this study had a significant correlation with development of GDM. High ferritin range was found in females with GDM. Routine use of monitoring of serum ferritin levels, during the antenatal visit in the mid trimester should be carried out, for early prediction of developing GDM.
Keywords: GDM, Serum ferrtin, Metabolic conditions.
Design, Development and Evaluation of Matrix Tablet
Authors: Chatterjee Arindam , Sharma Deeksha , Mishra Anuj 
Published: November 2021

Recently, sustained release formulations have become a very helpful tool in medical practice, providing patients with a variety of benefits. Sustained release is also a potential method for reducing pharmacological side effects by preventing fluctuations in the concentration of the drug in the plasma. Nowadays, relatively few pharmaceuticals are emerging from research and development, and current drugs are suffering from resistance as a result of their inappropriate usage. Thus, altering the operation is an appropriate and optimum method of increasing the effectiveness of a medicine by a little variation in the drug distribution. The release of the medication through such a system is regulated by both dissolution and diffusion processes. Most medications, if not correctly designed, may quickly release the drug at a higher pace, resulting in hazardous concentrations of the drug upon oral administration. This review discusses the fundamentals of sustained release formulations and the many varieties available.
Key words: Matrix tablets, Sustained release, Sustain release polymers, Patient convenience and compliance.
Keberadaan Plastik di Lingkungan, Bahaya terhadap Kesehatan Manusia, dan Upaya Mitigasi: Studi Literatur
Authors: Firmansyah Yura Witsqa , Fuadi Mirza Fathan , Ramadhansyah Muhammad Fadli , Sugiester S Farida , Widyantoro Wahyu , Lewinsca Maurend Yayank , Diyana Sutra , Marliana Nanda Ika Vera , Arumdani Intan Sekar , Pratama Aziz Yulianto , Azhari Desti , Sukaningtyas Ramadani , Hardiyanto Afdal 
Published: November 2021

Since 2001, synthetic polymers have been one of the most important materials since 2001 because they are used by humans and become a necessity in various sectors such as thermoplastics in countless quantities. Plastics have properties that are difficult to decompose and can change size into plastic macromolecules with the help of photodegradation, oxidation, hydrolytic degradation, and mechanical breakdown . Plastic pollution is a serious problem because the demand for plastic by society is increasing every year and the result of a lot of plastic waste can cause serious health problems and problems in the surrounding environment. Therefore, the use of plastic has a big impact on human health and the environment because it’s hard to decompose. The aim of this study is to provide information on the effects of microplastics on the environment through a review study. This study uses a descriptive method with a literature review approach. The criteria for articles used sources from Scopus, Science Direct, ProQuest, SpringerLink, Google Scholar, Nature, JSTOR, and Emerald Insight. The conclusion in this study found a relationship between the presence of microplastics with human health problems, and the environment so that it is necessary to mitigate against plastic waste pollution such as 3R and substitution of materials.
Pengetahuan dan Adaptasi Petani Kopi terhadap Perubahan Iklim di Kecamatan Air Hitam Kabupaten Lampung
Authors: Mutolib Abdul , Rahmat Ali , Sumiati Tita 
Published: November 2021

Climate change has caused production declines and crop failures in some agricultural commodities. This study aims to identify the level of knowledge, adaptation practices, and types of protective trees used by coffee farmers in dealing with climate change. The research was carried out in Rigis Jaya Village, West Lampung District from May to July 2021. The number of respondents was 80 coffee farming households. Respondents were determined through a simple random sampling approach. The data collected consists of qualitative and quantitative data. Data collection was carried out through the survey method. The results of the study illustrate that coffee farmers have realized that climate change has occurred. 60% of coffee farmers are aware of climate change in the last 1-5 years and 20% of coffee farmers are more than 5 years old. From mitigation practices, 25% of coffee farmers mitigate climate change. Climate change mitigation practices carried out by farmers are through the use of superior coffee varieties, planting shade trees, setting coffee spacing, making vents, and utilizing the remaining coffee husks to increase soil fertility and moisture. There are 14 types of shade trees planted by farmers consisting of legumes and non-legume trees. Petai (Parkia speciosa) is the most widely planted shade tree in coffee plantations with 45% of the total respondents.
Evaluasi Postur Kerja Operator Pemasangan Fire Brick Berbasis Metode Rapid Upper Limb Assessment dan Work Ergonomic Risk Assessment Di PT ABA
Authors: Shofiyyullah Muhammad , Mahbubah Nina Aini 
Published: November 2021

A service provider is known as a job that profoundly depends on human work. Musculoskeletal disorder is considered a risk in such work. PT. ABA is a contractor service company that provide some services. The fire brick installation is a part of the refractory project, which is carried out continuously at the customer's request. Early results using the Nordic Body Map questionnaire found severe risk, which may lead to wellbeing difficulty. This study aims to evaluate musculoskeletal disorder risk due to inappropriate posture in fire brick installation activities. Rapid Upper Limb Assessment and Work Ergonomic Risk Assessment are ergonomic risk approaches used in this study. This research found two final scores using RULA and WERA calculation. RULA final score is 44, classified as a medium score. The evaluation results of the RULA method obtained a final score of 7 with an extreme condition. An urgent improvement is a necessity in order to improve posture and work positioning of fire brick installation.
Butterfly Triple System Algorithm Based on Graph Theory
Authors: Ibrahim Haslinda , Aldiabat Raja'i Mohammad , Karim Sharmila 
Published: November 2021

In combinatorial design theory, clustering elements into a set of three elements is the heart of classifying data, which has recently received considerable attention in the fields of network algorithms, cryptography, design and analysis of algorithms, statistics, and Information theory. This article provides insight into formulating algorithm for a new type of triple system, called a Butterfly triple system. Basically, in this algorithm development, a starter of cyclic near-resolvable ((v-1)/2)-cycle system of the 2-fold complete graph 2Kvis employed to construct the starter of cyclic ((v-1)/2)-star decomposition of 2Kv. These starters are then decomposed into triples and classified as a starter of cyclic Butterfly triple. The obtained starter set generates a triple system of order v. A special reference for case ν ≡ 9 (mod 12) is presented to demonstrate the development of the Butterfly triple system.
Selective Image Segmentation Models Using Three Distance Functions
Authors: Abdullah Siti Aminah , Jumaat Abdul Kadir 
Published: November 2021

Image segmentation can be defined as partitioning an image that contains multiple segments of meaningful parts for further processing. Global segmentation is concerned with segmenting the whole object of an observed image. Meanwhile, the selective segmentation model is concerned with segmenting a specific object required to be extracted. The Convex Distance Selective Segmentation (CDSS) model, which uses the Euclidean distance function as the fitting term, was proposed in 2015. However, the Euclidean distance function takes time to compute. This paper proposes the reformulation of the CDSS minimization problem by changing the fitting term with three popular distance functions, namely Chessboard, City Block, and Quasi-Euclidean. The proposed models are CDSSNEW1, CDSSNEW2, and CDSSNEW3, which apply the Chessboard, City Block, and Quasi-Euclidean distance functions respectively. In this study, the Euler-Lagrange (EL) equations of the proposed models were derived and solved using the Additive Operator Splitting method. Then, MATLAB coding was developed to implement the proposed models. The accuracy of the segmented image was evaluated using the Jaccard (JSC) and Dice Similarity Coefficients (DSC). The execution time was recorded to measure the efficiency of the models. Numerical results showed that the proposed CDSSNEW1 model based on the Chessboard distance function could segment the specific object successfully for all grayscale images with the fastest execution time compared to other models.
Ensemble Feed-Forward Neural Network and Support Vector Machine for Prediction of Multiclass Malaria Infection
Authors: Jimoh Rasheed Gbenga , Abisoye Opeyemi Aderiike , Uthman Muhammed Mubashir Babatunde 
Published: November 2021

Globally, recent research are focused on developing appropriate and robust algorithms to provide a robust healthcare system that is versatile and accurate. Existing malaria models are plagued with low rate of convergence, overfitting, limited generalization due to restriction to binary cases prediction, and proneness to local minimum errors in finding reliable testing output due to complexity of features in the feature space, which is a black box in nature. This study adopted a stacking method of heterogeneous ensemble learning of ArtificialNeural Network (ANN) and Support Vector Machine (SVM) algorithms to predict multiclass, symptomatic, and climatic malaria infection. ANN produced 48.33 percent accuracy, 60.61 percent sensitivity, and 45.58 percent specificity. SVM with Gaussian kernel function gave better performance results of 85.60 percent accuracy, 84.06 percent sensitivity, and 86.09 percent specificity. Consequently, to improve prediction performance, a stacking method was introduced to ensemble SVM with ANN. The proposed ensemble malaria model was tuned on different thresholds at a threshold value of 0.60, the ensemble model gave an optimum accuracy of 99.86 percent, sensitivity 100 percent, specificity 98.68 percent, and mean square error 0.14. The ensemble model experimental results indicated that stacked multiple classifiers produced better results than a single model. This research demonstrated the efficiency of heterogeneous stacking ensemble model on effects of climatic variations on multiclass malaria infection classification. Furthermore, the model reduced complexity, overfitting, low rate of convergence, and proneness to local minimum error problems of multiclass malaria infection in comparison to previous related models.
Evaluation of the effects of donepezil, memantine and α-lipoic acid combined administration in amnesia rats on impaired cognitive functions in terms of behavioural, apoptotic, cholinergic and glutamatergic systems
Authors: AYKAÇ Aslı , ÖZBEYLİ Dilek , PEKOL Gizem , ŞEHİRLİ Ahmet Özer 
Published: November 2021

Objective: The aim of the study was to evaluate the possible protective effects of alpha-lipoic acid (α-LA), donepezil and memantine combined therapy in the scopolamine-induced amnesia rat model.
Objective: The aim of the study was to evaluate the possible protective effect of donepezil, memantine and alpha-lipoic acid (α-LA) combined therapy in the scopolamine-induced amnesia rat model.
Methods: In this study, the effect of combined therapy used in the treatment of scopolamine-induced amnesia on behavioural parameters was evaluated using Y-maze and new object recognition (NOR) test. In addition, muscarinic acetylcholine receptor subtype M1, N-methyl-D-aspartate receptor NR2B subunit, brain-derived neurotrophic factor (BDNF) and mitochondrial apoptosis-related proteins [B-cell lymphoma-2 (Bcl-2) / Bcl-2 associated X (Bax) ratio, caspase (casp) -3, and -9] expression levels were evaluated using the western blot method in the frontal cortex and hippocampus regions.
Results: The main findings of this study demonstrated that in scopolamine-induced amnesia rats, cognitive dysfunction determined by both the Y-maze and the NOR test were reversed with the combined treatment of memantine, donepezil and α-LA. According to immunoblotting results in both brain regions, scopolamine-induced decreased M1, BDNF, Bcl-2 / Bax ratio and increased NR2B, casp-3 and -9 expression levels were found to be reversed to almost control values with combined treatment.
Conclusion: Consistent with the literature, our study results suggest that the positive contribution of α-LA to the combined treatment of donepezil and memantine, which is used in the routine treatment of neurodegenerative diseases, may be a treatment option in the future.
Results: The main findings of this study demonstrated that in scopolamine-induced amnesia rats, cognitive dysfunction determined by both the Y-maze and the NORT test were reversed with the combined treatment of memantine, donepezil and α-LA. In addition, decreased BDNF, M1, bcl-2/bax ratio and increased NR2B, caspase-3 and caspase-9 expression levels due to scopolamine in both regions were improved with α-LA, donepezil and memantine combined therapy.
Conclusion: The results of our study and other study results in the literature suggest that α-LA may be a future treatment option due to its positive contribution to the effects of other drugs used in the routine treatment of neurodegenerative diseases.
The Estimation of Standard Portion Sizes Using Food Photographic Booklet Among University Students in Turkey
Authors: ALMASİ Negin , RAKICIOĞLU Neslişah 
Published: November 2021

Objective: To examine estimation of standard portion size and, the influence of different food plates on the estimation of food portion size, using photograph booklet in students.
Methods: The sample consisted of 300 students, aged 18-35 years old from different academic departments. The student’s general characteristics were asked by using a questionnaire, and anthropometric measurements were taken. Students were asked to select the standard portion sizes of each food from a photographic booklet, which was developed by the researchers. Dietary guidelines for Turkey were used for assessing the quantity of standard portion size of foods of a photographic booklet (1).
Results: The findings of the present study indicate that the food group which the most students provided the accurate estimation was protein foods (36.0%), pursued by grains (35.1%), dairy (29.2%), fruits and vegetables group (28.9%). The most and the least accurate estimated foods were found boiled potato (64%) and cheese (3.7%), respectively. The percentages of the accurate estimation of standard portion size for five foods (meatball, meat cubes, shredded chicken, egg, yogurt) in 24 foods were higher in females than men (p
TIME PERSPECTIVE PERCEPTION SPECIFIC AND MALADAPTATION IN ELDERLY UNDER UNCERTAINTY CONDITIONS DURING PANDEMIC EMERGENCY
Authors: Васильева А.В. , Антохина Р.И. , Антохин Е.Ю. 
Published: November 2021

Цель исследования - определение специфики переживания психологического стресса, временной перспективы и симптоматики адаптационных нарушений у пожилых людей в чрезвычайной ситуации пандемии по сравнению с активным взрослым населением. На первом этапе были обследованы 587 человек с помощью шкалы PSM-25, затем были отобраны 100 респондентов с дезадаптационным уровнем стресса (сумма ≥155 баллов). Основную группу составили 50 человек 60-74 лет (средний возраст - 65±2,7 года), 50 человек 18-44 лет (средний возраст - 32±3,8 года) вошли в группу сравнения, которые были обследованы с помощью опросника SCL-90-R для оценки психопатологической симптоматики и опросника ZTPI для оценки восприятия временной перспективы. Выявлено наличие адаптационных расстройств в обеих группах. В группе пожилых установлена активация восприятия позитивного прошлого, что может быть адаптационным ресурсом, и большая выраженность фаталистического восприятия настоящего, что обусловливает пассивное преодоление стресса и сужает адаптационные возможности пожилых людей. Результаты исследования позволяют обозначить потенциальные «мишени» психотерапевтической работы с населением в условиях пандемического стресса с учетом возрастного фактора.
The purpose of the study - to determine the specifics of experiencing psychological stress, the time perspective and symptoms of adaptation disorders in older people in a pandemic emergency compared to the active adult population. At the first stage, 587 people were examined using the PSM-25 scale, then 100 respondents with maladaptive stress levels (sum ≥155 points) were selected. The main group consisted of 50 people aged 60 to 74 years (aver age age 65±2,7 years), 50 people aged 18 to 44 years (average age 32±3,8 years) were included in comparison group, who were examined with using the SCL-90-R questionnaire for assessing psychopathological symptoms and the ZTPI questionnaire for assessing the perception of time perspective. The presence of adaptation disorders in both groups was revealed. In the elderly group, the activation of the perception of the positive past was established, which can be an adaptive resource, and the greater severity of the fatalistic perception of the present, which causes passive overcoming with stress and narrows the adaptive capabilities of the elderly. The results of the study make it possible to identify potential «targets» of psychotherapeutic work with the population in conditions of pandemic stress, taking into account the age factor.
THE PROBLEMS OF OLDER PEOPLE AND DIRECTIONS OF MEDICAL, SOCIAL AND PSYCHOLOGICAL SUPPORT DURING THE COVID-19 PANDEMIC
Authors: Решетова Т.В. , Лаптева Е.С. , Лукашкова В.В. , Решетов А.В. 
Published: November 2021

В обзорной статье рассмотрены медицинские, психологические и социальные проблемы людей пожилого возраста в связи с пандемией. Продемонстрировано негативное влияние хронического стресса на формирование психопатологических расстройств (тревога, астения, паника, когнитивная дисфункция). На основании результатов собственного клинического опыта лечения и психологической коррекции этих психопатологических расстройств у людей старшего поколения, переживавших пандемию, а также по итогам аналогичных результатов других исследователей в разных странах, проведён анализ методов психологической поддержки при различных психопатологических расстройствах у пожилых людей. На основании результатов собственных исследований в период пандемии выявлено увеличение частоты астении и психосоматических расстройств у пациентов. Представлены алгоритмы дифференциальной диагностики и лечения астении в рамках постковидного синдрома. Описаны особенности опыта самоизоляции для пожилых людей в разных странах, проанализированы причины психической дезадаптации, формирования аддикций. Продемонстрированы алгоритм и итоги психологической поддержки, оказанной людям старшего поколения в формате работы организации социально-психологической помощи.
The review article examines the medical, psychological and social problems that older people face due to the pandemic. The article contains the analysis of the mortality rate in the older age group in different countries. It also demonstrates the negative impact of the pandemic stress on the formation of psychopathological disorders (anxiety, asthenia, panic, cognitive dysfunction). The authors carried out an analysis of psychological support methods for various psychopathological disorders among the elderly, based on both the results of their own clinical experience in the treatment and psychological correction of the disorders of older people experiencing the pandemic, and similar results of other researches in other countries. The results of the presented research during the pandemic suggest that the frequency of asthenia and psychosomatic disorders in patients was increased. The paper presents algorithms for the differential diagnosis and treatment of asthenia as part of the post-covid syndrome. The article contains an objective scientific and practical assessment of the experience of self-isolation for the elderly, as well as the analysis of the reasons for mental maladjustment and the formation of addictions. The algorithm and the results of psychological support, provided to older people by a psychosocial support organization, are demonstrated.