bluuebunny/crossref_metadata_2025_split huggingface dataset:
Network interactions for pharmaceutical market access: findings from an explorative research
Authors: Runfola Andrea , Guercini Simone , Milanesi Matilde 
Published: September 2021

Purpose
The purpose of this paper is to investigate pharmaceutical market access (MA) and the interaction between the pharmaceutical company and other business and non-business actors (NBAs) involved in the MA of ethical drugs, to identify the main categories of actors, their role for MA and the content of the interaction, adopting an industrial marketing approach.

Design/methodology/approach
A qualitative interpretivist approach is adopted, with interviews as the primary data collection method: 36 interviews have been conducted with 16 key informants from the pharmaceutical industry.

Findings
The findings of this study reveal that (i) MA can be seen as a relational-driven activity with specific features owing to the highly regulated nature of the pharmaceutical industry, (ii) there is a multiplicity of business, and NBAs involved in the MA activities with whom pharmaceutical companies interact to acquire knowledge, legitimacy and make MA timely and effective, and (iii) the interaction with each category of actors has specific content.

Originality/value
This paper advances the debate on the marketing and management of pharmaceutical companies by emphasizing the importance of MA and the need to conceptualize it according to an industrial marketing perspective, revealing the interdependencies among actors for MA and the content of the interaction. It also contributes to the industrial marketing literature that has recently stressed the importance of NBAs as part of the extended business network of a company by identifying different categories of actors, their role in terms of knowledge and legitimization and the features and the trade-off of the extended business network in highly regulated markets.
Numerical modelling of fire test with timber fire protection
Authors: Šálek Vojtěch , Cábová Kamila , Wald František , Jahoda Milan 
Published: September 2021

PurposeThe purpose of this paper is to present a complex pyrolysis computational fluid dynamics (CFD) model of timber protection exposed to fire in a medium size enclosure. An emphasis is placed on rarely used temperature-dependent thermal material properties effecting the overall simulation outputs. Using the input dataset, a fire test model with oriented strand boards (OSB) in the room corner test facility is created in Fire Dynamics Simulator (FDS).Design/methodology/approachSeven FDS models comprising different complexity approaches to modelling the burning of wood-based materials, from a simplified model of burning based on a prescribed heat release rate to complex pyrolysis models which can describe the fire spread, are presented. The models are validated by the experimental data measured during a fire test of OSB in the room corner test facility.FindingsThe use of complex pyrolysis approach is recommended in real-scale enclosure fire scenarios with timber as a supplementary heat source. However, extra attention should be paid to burning material thermal properties implementation. A commonly used constant specific heat capacity and thermal conductivity provided poor agreement with experimental data. When the fire spread is expected, simplified model results should be processed with great care and the user should be aware of possible significant errors.Originality/valueThis paper brings an innovative and rarely used complex pyrolysis CFD model approach to predict the behaviour of timber protection exposed to fire. A study on different temperature-dependent thermal material properties combined with multi-step pyrolysis in the room corner test scenario has not been sufficiently published and validated yet.
Workplace spirituality, well-being at work and employee loyalty in a gig economy: multi-group analysis across temporary vs permanent employment status
Authors: Aboobaker Nimitha , Edward Manoj , Zakkariya K.A. 
Published: September 2021

PurposeThis study aims to examine the influence of workplace spirituality on employee loyalty toward the organization, mediated through well-being at work. Furthermore, the study endeavors to test the difference in conceptual model estimates, across two groups of employees: those who work on contract/temporary and permanent basis. The study gains relevance particularly in the context of the emerging sharing economy, where jobs are primarily characterized by short-term contracts and freelancing.Design/methodology/approachThis descriptive study was conducted among a sample of 523 educators working in private educational institutions in India. Self-reporting questionnaires were administered among the respondents, who were selected through the purposive sampling method. Structural equation modeling and multi-group analysis were done to test the proposed hypotheses.FindingsThe analysis revealed that workplace spirituality enriched employee well-being and loyalty toward the organization and evidence were found for indirect effects too. Variances were observed in the relationships, with respect to the different employment statuses of the personnel. Significant differences in the relationships were not found across temporary and permanent employment statuses. Interestingly, temporary employees experienced stronger influences between meaningful work, well-being and word-of-mouth. Results suggest the relevance of understanding employees' differential work experiences and attitudes and thus facilitate human resource strategies accordingly.Originality/valueThis study is pioneering in conceptualizing and testing a theoretical model linking workplace spirituality, well-being at work and employee loyalty, particularly in the context of employees who differ in their employment status, which is a critical aspect of modern-day organizations. Unlike traditional workplaces, in recent times, people come together and work along for shorter terms, as the case of a sharing economy and the thus emergent interpersonal dynamics between each other and with the workplace has significant repercussions on the organization. Theoretical and managerial implications with regard to the experience of workplace spirituality and job outcomes are elaborated, thus striving to fill a gap in the existing literature.
Interview-based research in management and organisation studies: making sense of the plurality of methodological practices and presentational styles
Authors: Reissner Stefanie , Whittle Andrea 
Published: September 2021

PurposeThe aim of this review paper is to identify the methodological practices and presentational styles used to report interview-based research in “leading” management and organisation journals.Design/methodology/approachThis paper reviews a sample of 225 articles using qualitative interviews that were published in management, human resource management, organisational behaviour and international business journals listed in the Financial Times 50 list between 2009 and 2019.FindingsThe review found diversity and plurality in the methodological practices used in these studies and the presentational styles used to report interview research.Practical implicationsThe findings are expected to help doctoral students, early career scholars and those new to using qualitative interviews to make decisions about the appropriateness of different methodological practices and presentational styles. The findings are also expected to support editors, reviewers, doctoral examiners and conference organisers in making sense of the dissensus that exists amongst qualitative interview researchers (Johnson et al., 2007). These insights will also enable greater “paradigmatic awareness” (Plakoyiannaki and Budhwar, 2021, p. 5) in the evaluation of the quality of interview-based research that is not restricted to standardised criteria derived from positivism (Cassell and Symon, 2015).Originality/valueTo make sense of this plurality, the authors map these practices and styles against the onto-epistemological paradigms identified by Alvesson (2003, 2011). The paper contributes to calls for philosophical diversity in the evaluation of qualitative research. The authors specifically articulate concerns about the use of practices in interview-based studies that derive from the positivistic logic associated with quantitative research.
The role of personality traits in promoting customer citizenship behaviour: special reference to the homestay tourism context in Sri Lanka
Authors: Lakmali Shanika , Kajendra Kanagasabai 
Published: September 2021

PurposeThis study aims to explore customer personality traits as an antecedent of customer citizenship behaviour which positively facilitates service providers.Design/methodology/approachThis study follows the positivism research paradigm. Hence, primary data were collected from 250 homestay visitors who stayed at five selected homestays located at Mirissa homestay zone, Sri Lanka.FindingsThe present study's findings reveal that “agreeableness,” “extraversion” and “conscientiousness” personality traits promote customer citizenship behaviour. Furthermore, the openness to “experience” trait identified to have a statistically insignificant relationship with CCB and neuroticism recorded a positive impact on the relationship between CCB and personality, contrary to the existing literature.Practical implicationsThis study comprehensively explains how service providers should arrange their service facilities to increase customer willingness to perform citizenship behaviour, which helps develop their services.Originality/valuePrevious research has investigated that customer personality in terms of prosocial and proactive nature impacts CCBs. In contrast, the effect of Big Five personality traits on CCB is highlighted in this study.
Disaster relief efforts of Houston sport organizations
Authors: Finch Bryan 
Published: September 2021

PurposeThe purpose of this paper is to examine the community recovery efforts undertaken by Houston, Texas, sport organizations following Hurricane Harvey in 2017.Design/methodology/approachForty-eight media articles, 138 social media posts from Houston athletes and five semi-structured interviews with Houston sport organization executives underwent a content analysis to categorize responses of disaster relief activities. All eleven categories were identified. Three themes emerged from additional analysis: organizations serving as communication hubs, earned trust and internal organizational support. Benchmark examples in key categories are also discussed.FindingsThis paper provided focused analysis of the reactions of several Houston area sport organizations during the immediate disaster recovery period. Organizations participated in both tangible and emotional recovery efforts. The long-term impacts of these efforts will require additional investigation. The findings of this case study are specific to the relief efforts in Houston, Texas, following Hurricane Harvey in 2017 and may not be generalizable beyond this scope.Practical implicationsSport organizations and community leaders can better prepare for future disaster responses by gaining insight into the roles and procedures enacted by the Houston teams following the Hurricane in 2017.Originality/valueThis study provides a detailed examination of the responses of several Houston sport organizations following Hurricane Harvey, including perspectives from executives inside of the organizations. Utilizing social anchor theory, this paper expands our understanding of the impacts sport organizations may produce in their roles as social anchors during disaster relief and recovery.
The impact of climate change on aggregate output in middle‐ and high‐income countries
Authors: Doğanlar Murat , Mike Faruk , Kızılkaya Oktay 
Published: September 2021

AbstractThis study aims to analyse the impact of climate change on the aggregate output of middle‐ and high‐income countries by using dynamic panel data analysis for yearly observations from 1990 to 2016. Following the Cobb–Douglas production function, the analyses included key economic parameters which are capital stock, labour force, and total factor productivity, and also climate change indicators namely temperature and precipitation. The generalised method of moments test results revealed different findings for middle‐ and high‐income countries. Both the temperature and precipitation variables had a negative and statistically significant impact on aggregate output for middle‐income countries. In the high‐income countries, the temperature was found to have a positive but negligible effect on aggregate output, whereas precipitation was not found to have any significant effect. Granger causality test is also conducted to check for the consistency of GMM estimation.
Extracorporeal blood purification is associated with improvement in biochemical and clinical variables in the critically‐ill COVID‐19 patients
Authors: Premužić Vedran , Babel Jakša , Gardijan Danilo , Lapić Ivana , Gabelica Rajka , Ostojić Zvonimir , Lozić Marin , Pavliša Gordana , Hrabak Maja , Knežević Josip , Rogić Dunja , Mihaljević Slobodan 
Published: September 2021

AbstractThis study tried to investigate the impact of oXiris filter on both clinical and laboratory parameters in critically‐ill COVID‐19 intensive care unit (ICU) patients receiving extracorporeal blood purification and the clinical setting for the initiation of therapy. A consecutive sample of 15 ICU patients with COVID‐19 was treated with oXiris membrane for blood purification or for support of renal function due to acute kidney injury. We have included 19 non treated ICU COVID‐19 patients as a control group. Two chest x‐rays were analyzed for determining the chest x‐ray severity score. We have found a significant decrease of SOFA score, respiratory status improved and the chest x‐ray severity score was significantly decreased after 72 h of treatment. IL‐6 significantly decreased after 72 h of treatment while other inflammatory markers did not. Respiratory status in the control group worsened as well as increase in SOFA score and chest x‐ray severity score. Survived patients have shorter time from the onset of symptoms before starting with extracorporeal blood purification treatment and shorter time on vasoactive therapy and invasive respiratory support than deceased patients. Critically‐ill patients with COVID‐19 treated with extracorporeal blood purification survived significantly longer than other ICU COVID‐19 patients. Treatment with oXiris membrane provides significant reduction of IL‐6, leads to improvement in respiratory status, chest x‐ray severity score, and reduction of SOFA score severity. Our results can suggest that ICU COVID‐19 patients in an early course of a disease could be potentially a target group for earlier initiation of extracorporeal blood purification.
Festschrift initiative: Celebrating Emeritus Professor Ruth Fincher AM
Authors: Stratford Elaine 
Published: September 2021

AbstractProfessional and society journals often publish obituaries in which colleagues reflect on and celebrate the lives of others—in this instance, geographers—who are no longer with us and who have been closely associated with a discipline and sometimes also with a country or region. Less often do journal editors and contributors curate collections of works that recognise and reflect upon the sustained contributions made by colleagues who are still with us. Festschrift offerings such as the kind I am thinking of are almost unheard of in this journal. We begin to remedy that gap now because such offerings show colleagues’ influences on us and the discipline. To those ends, this inaugural offering celebrating Ruth Fincher initiates what I hope will be the first of many in coming years.
Relative Performance Evaluation and Earnings Management*
Authors: Infuehr Jakob 
Published: September 2021

ABSTRACTConventional agency theory suggests that firms should benchmark CEO compensation to absorb systemic risk and to more efficiently incentivize executives to work hard. Yet empirical research has found only a modest use of benchmarking in CEO compensation contracts. In this paper, I highlight one weakness of relative performance evaluation (RPE). When earnings management is possible, benchmarking creates stronger incentives for misreporting performance measures compared to benchmark‐independent pay. The optimal contract will depend less on a correlated benchmark (e.g., a stock market index) if it is easier for the manager to misreport performance. Thus, the model predicts that firms with weak internal controls and bad auditors are less likely to use RPE, offering a theoretical explanation for the empirically observed lack of RPE use.
Venous thromboembolism in women with ovarian cancer undergoing neoadjuvant chemotherapy prior to cytoreductive surgery: A retrospective study
Authors: Oxley Samuel G. , Achampong Yaa A. , Sambandan Nikola , Hughes Daniel J. , Thomas Mari , Lockley Michelle , Olaitan Adeola 
Published: September 2021

AbstractIntroductionOvarian cancer is associated with a venous thromboembolism risk of at least 7.2% by 2 years from diagnosis, and although patients undergoing surgery benefit from routine thromboprophylaxis, those undergoing neoadjuvant chemotherapy do not. This study aims to determine the venous thromboembolism incidence in patients with ovarian cancer undergoing neoadjuvant chemotherapy, and explore whether any subset is at higher risk, in order to evaluate whether thromboprophylaxis is justified in some or all of these patients.Material and methodsThis was a retrospective review of all women undergoing neoadjuvant chemotherapy for FIGO radiological stages III and IV primary ovarian, fallopian tube, and primary peritoneal cancer, between 2000 and 2015, in a London tertiary cancer center. The primary outcome was venous thromboembolism rate among women undergoing neoadjuvant chemotherapy. The secondary outcomes were patient or treatment factors associated with venous thromboembolism risk, including age, body mass index, smoking status, performance status, and tumor stage.ResultsWe identified 278 eligible women from the ovarian cancer database. Fifty‐eight women (20.9%) developed venous thromboembolism between initial presentation and the immediate postoperative period, of which 45 (77.6%) developed a pulmonary embolism. In all, 15.1% of women developed venous thromboembolism from the start of neoadjuvant chemotherapy. Age, body mass index, smoking, or other comorbidities were not significantly associated with venous thromboembolism risk. One woman died from massive pulmonary embolism, 27 women underwent inferior vena cava filter insertion, and 10 had surgery delayed.ConclusionsThis study demonstrates an unacceptably high rate of avoidable venous thromboembolism including pulmonary embolism in these women, which complicates and delays treatment. Thromboprophylaxis during neoadjuvant chemotherapy should now be assessed prospectively.
Addition of 3‐methoxytyramine or chromogranin A to plasma free metanephrines as the initial test for pheochromocytoma and paraganglioma: Which is the best diagnostic strategy
Authors: Liu Lu , Xie Wenchun , Song Zhijing , Wang Tianyu , Li Xuesong , Gao Ying , Li Yan , Zhang Junqing , Guo Xiaohui 
Published: September 2021

AbstractObjectiveMeasurements of plasma free metanephrines (MNs), including MN and normetanephrine, provide high sensitivity and specificity for the diagnosis of pheochromocytoma and paraganglioma (PPGL). 3‐Methoxytyramine (3‐MT) and chromogranin A (CgA) may allow the detection of dopamine‐producing or biochemically silent PPGL. The aim of this study was to evaluate whether measurements of plasma 3‐MT or CgA as a supplement of plasma MNs offer a better diagnostic strategy for initial testing of PPGL.Patients and DesignWe enroled 125 patients who underwent surgery from 2015 to 2016 for our study and identified 33 patients with PPGL and 92 patients with non‐PPGL masses.MeasurementThe levels of plasma free MNs and 3‐MT were measured for all 125 patients using liquid chromatography–tandem mass spectrometry. Plasma CgA concentrations were determined using a radioimmunoassay. To evaluate the diagnostic performance of plasma free MNs, 3‐MT and CgA, sensitivity and specificity were determined, and receiver operating characteristic curves were constructed.ResultsWe found that combining 3‐MT and MNs increased the diagnostic sensitivity from 93.9% (95% confidence interval [CI]: 78.4%–98.9%) to 97.0% (95% CI: 82.5%–99.8%). In contrast, addition of plasma CgA test reduced the diagnostic specificity significantly from 91.3% (95% CI: 83.1%–95.9%) to 75.0% (95% CI: 64.7%–83.2%).ConclusionHere, we demonstrated that 3‐MT represents a valuable supplementary test to plasma MNs, which can further enhance the sensitivity of the assay, while plasma CgA added no additional diagnostic value to MNs due to the lowered diagnostic specificity.
Bright spots as climate‐smart marine spatial planning tools for conservation and blue growth
Authors: Queirós Ana M. , Talbot Elizabeth , Beaumont Nicola J. , Somerfield Paul J. , Kay Susan , Pascoe Christine , Dedman Simon , Fernandes Jose A. , Jueterbock Alexander , Miller Peter I. , Sailley Sevrine F. , Sará Gianluca , Carr Liam M. , Austen Melanie C. , Widdicombe Steve , Rilov Gil , Levin Lisa A. , Hull Stephen C. , Walmsley Suzannah F. , Nic Aonghusa Caitriona 
Published: September 2021

AbstractMarine spatial planning that addresses ocean climate‐driven change (‘climate‐smart MSP’) is a global aspiration to support economic growth, food security and ecosystem sustainability. Ocean climate change (‘CC’) modelling may become a key decision‐support tool for MSP, but traditional modelling analysis and communication challenges prevent their broad uptake. We employed MSP‐specific ocean climate modelling analyses to inform a real‐life MSP process; addressing how nature conservation and fisheries could be adapted to CC. We found that the currently planned distribution of these activities may become unsustainable during the policy's implementation due to CC, leading to a shortfall in its sustainability and blue growth targets. Significant, climate‐driven ecosystem‐level shifts in ocean components underpinning designated sites and fishing activity were estimated, reflecting different magnitudes of shifts in benthic versus pelagic, and inshore versus offshore habitats. Supporting adaptation, we then identified: CC refugia (areas where the ecosystem remains within the boundaries of its present state); CC hotspots (where climate drives the ecosystem towards a new state, inconsistent with each sectors’ present use distribution); and for the first time, identified bright spots (areas where oceanographic processes drive range expansion opportunities that may support sustainable growth in the medium term). We thus create the means to: identify where sector‐relevant ecosystem change is attributable to CC; incorporate resilient delivery of conservation and sustainable ecosystem management aims into MSP; and to harness opportunities for blue growth where they exist. Capturing CC bright spots alongside refugia within protected areas may present important opportunities to meet sustainability targets while helping support the fishing sector in a changing climate. By capitalizing on the natural distribution of climate resilience within ocean ecosystems, such climate‐adaptive spatial management strategies could be seen as nature‐based solutions to limit the impact of CC on ocean ecosystems and dependent blue economy sectors, paving the way for climate‐smart MSP.