bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERUBAHAN PREMIUM INCOME DAN INVESTMENT RESULTS PT. AXA MANDIRI SYARIAH DAN IMPLIKASINYA TERHADAP TABARRU FUND RESERVE
Authors: Suja’i Wilda Waladiah Ibnu , Huda Badriyatul 
Published: February 2021

AbstractThis paper is motivated by a phenomenon shows that the Premium Income and Investment Results at PT. AXA Mandiri Syariah experiences fluctuations, both of which have a direct impact on the condition of the Tabarru Fund Reserve. Therefore, this article aims to analyze the effect of official income and investment hail on tabarru fund reserves both partially and simultaneously. This article also uses descriptive methods and quantitative approaches, namely to describe the results of the research, the data of which are presented in numerical form. The data in this article is secondary data taken from the financial statements of PT. AXA Mandiri Syariah and supported by literature study and documentation, which are processed statistically and quantitatively. The results of this study concluded that Premium Income has a significant effect on the Tabarru Fund Reserve by 100%. Then, the investment return also has a significant effect on the Tabarru Fund Reserve by 88.4%. Finally, both simultaneously have a significant effect on the Tabarru Fund Reserve by 100%. The implication of this research is that insurance companies need to increase Premium Income and Investment Results because both have a significant effect on increasing the Tabarru Fund Reserve. Keywords: Premium Income, Investment Result, Tabarru Fund Reserve, Islamic Insurance AbstrakTulisan ini dilatarbelakangi fenomena yang menunjukan bahwa Premium Income dan Investment Results pada PT. AXA Mandiri Syariah mengalami fluktuasi yang mana keduanya berdampak langsung kepada kondisi Tabarru Fund Reserve. Oleh karena itu, artikel ini bertujuan untuk menganalisis pengaruh pendapatan presmi tersebut dan hail investasi terhadap cadangan dana tabarru baik secara parsial dan simultan. Artikel ini juga menggunakan metode deskriptif dan pendekatan kuantitatif, yakni untuk mendeskripsikan hasil penelitian yang datanya disajikan dalam bentuk numerik. Data pada artikel ini merupakan data sekunder yang diambil dari laporan keuangan PT. AXA Mandiri Syariah dan didukung dengan studi kepustakaan dan dokumentasi, yang diolah scara statistik dan kuantitatif. Hasil penelitian ini menyimpulkan bahwa Premium Income berpengaruh signifikan terhadap Tabarru Fund Reserve sebesar 100%. Lalu, hasil investasi juga berpengaruh signifikan terhadap Tabarru Fund Reserve sebesar 88,4%. Terakhir, secara simultan keduanya juga berpengaruh signifikan terhadap Tabarru Fund Reserve sebesar 100%. Implikasi dari penelitian ini adalah perusahaan asuransi perlu meningkatkan Premium Income dan Investment Results, karena keduanya berpengaruh signifikan untuk mening­katkan Tabarru Fund Reserve Kata kunci: Premium Income, Investment Result, Tabarru Fund Reserve, Islamic Insurance
Consciências Saudáveis e Almas Enfermas: Posturas Éticas Religiosas em William James
Authors: Benevides Rodrigo Barbosa Gomes 
Published: February 2021

Trata-se aqui de examinar as noções de Sick Soul e Healthy-Mindedness de acordo com William James em sua obra Varieties of Religious Experience: A Study in Human Nature (1902). O pragmatismo de James se preocupa com o fenômeno religioso em termos de utilidade de um conjunto de crenças que fundamentam ações no campo ético e, desse prisma, James percebe a religião como ferramenta fundamental para o equilíbrio psíquico humano. Dito isso, o artigo apresenta os dois tipos básicos de postura ética aludidos, além de definir o que significa religião segundo James.
Persepsi Masyarakat dan Potensi Public Acceptance Terkait Wacana Pembangunan PLTN di Kabupaten Bengkayang
Authors: Herawati Netty , Sudagung Adityo Darmawan 
Published: February 2021

Pembangkit Listrik Tenaga Nuklir (PLTN) merupakan salah satu jenis pembangkit yang memiliki kelebihan dalam menghasilkan kapasitas listrik yang besar, stabil dan murah. Kelebihan tersebut menjadikan PLTN sebagai salah satu pilihan untuk memenuhi tuntutan ketersediaan listrik yang besar agar dapat menunjang perekonomian berbasis industri di Indonesia. Kabupaten Bengkayang merupakan salah satu daerah yang memiliki potensi untuk dijadikan lokasi tapak PLTN di Kalimantan Barat. Berkaitan dengan pemikiran tersebut, maka perlu dilakukan kajian untuk mengetahui bagaimana persepsi masyarakat serta potensi ‘’public acceptance’’ sehubungan dengan adanya wacana untuk membangun PLTN di Kalimantan Barat. Tujuan penelitian ini adalah pemaparan kualitatif mengenai persepsi masyarakat di Kabupaten Bengkayang. Metode pengumpulan data dilakukan melalui teknik observasi, wawancara mendalam serta studi literatur. Hasil penelitian menunjukkan bahwa pengetahuan masyarakat Bengkayang tentang nuklir dan PLTN masih sangat terbatas. Hal ini ditunjukkan oleh minimnya wawasan dan pemahaman masyarakat tentang nuklir hampir di semua lapisan. Persepsi masyarakat tentang nuklir pun keliru dengan mengidentikkan nuklir dengan bom dan selalu mengkaitkan PLTN dengan bahaya radiasi dan kecelakaan nuklir. Selain itu, ada kecenderungan masyarakat untuk setuju dan menerima rencana pemerintah untuk membangun PLTN dengan catatan pemerintah dapat menjamin keamanan dan masyarakat mendapat keuntungan dan mafaat yang jelas sebagai dampak kehadiran PLTN di wilayahnya. Kesimpulan dari penelitian ini adalah sikap penerimaan masyarakat tidak sepenuhnya dibangun dari aspek pemahaman publik, namun lebih ditentukan faktor kepentingan dan harapan masyarakat untuk memperbaiki kesejahteraannya
PERHITUNGAN SEL BAHAN BAKAR REAKTOR PWR DENGAN PROGRAM WIMSD-5B
Authors: Rajagukguk Santo Paulus , Bakhri Syaiful , Surbakti Tukiran 
Published: February 2021

Perhitungan sel bahan bakar teras reaktor PWR telah dilakukan dengan menggunakan program komputer WIMSD-5B. Perhitungan dilakukan untuk mengetahui karakteristik neutronik bahan bakar teras reaktor PWR dengan variasi daya. Karakteristik neutronik diketahui dengan memperoleh konstanta makroskopik seperti k-inf, koefisien difusi, tampang lintang serapan dan fisi. Generasi sel bahan bakar dilakukan dengan 69 grup energi neutron pada program transport satu dimensi (WIMSD-5B) menggunakan ENDF-BVII.1 data file. Sel satuan diperhitungkan pada perangkat elemen bakar dengan model cluster dengan susunan square pitch, kemudian dihitung dimensi satuan selnya. Satu satuan sel terdiri dari satu satuan bahan bakar dan moderator. Dari satu satuan sel ekivalen tersebut diperoleh data dimensi sel sebagai data masukan program WIMSD-5B yang dikenal dengan annulus. Bahan bakar yang digunakan adalah UO2 dan bentuk geometrinya pin cell bahan bakar. Hasil perhitungan faktor multiplikasi tak terhingga sel teras PWR yang dihitung dengan menggunakan paket program WIMSD-5B adalah 1,302338 dan fraksi bakar 37,12 GWD/TU. Dari hasil perhitungan dapat dinyatakan bahwa nilai faktor multiplikasi tak terhingga, konstanta difusi, tampang lintang serapan dan nu-fisi sangat dipengaruhi oleh bentuk model yang digunakan.Kata kunci: bahan bakar, teras PWR, WIMSD-5B, energi neutron, konstanta makroskopik
BAGAIMANA DAMPAK TRANSAKSI NON TUNAI DAN INFLASI TERHADAP JUMAH UANG YANG BEREDAR
Authors: Fatmawati Meilinda Nur Rasyida , Indah Yuliana  
Published: February 2021

ABSTRAK
Transaksi non tunai kini semakin banyak digunakan dalam bertransaksi. Selain lebih praktis, mudah dan cepat, transaksi non tunai memiliki pengaruh terhadap kebijakan moneter di Indonesia. Dalam kebijakan moneter, transaksi non tunai mempengaruhi tingkat jumlah uang beredar di masyarakat. Selain itu, terdapat faktor lain yang dapat mempengaruhi jumlah uang beredar yaitu inflasi. Transaksi non tunai pada penelitian ini menggunakan ATM debet, ATM kredit dan uang elektronik. Tujuan penelitian ini adalah untuk mendapatkan bukti pengaruh transaksi non tunai terhadap jumlah uang beredar di Indonesia dengan inflasi sebagai variabel moderasi selama tahun 2015- 2018. Pengumpulan data menggunakan data sekunder dan teknik analisis yang digunakan adalah uji Moderating Regression Analysis (MRA). Berdasarkan hasil penelitian yang telah dilakukan adalah transaksi non tunai memiliki pengaruh positif dan signifikan terhadap jumlah uang beredar dan inflasi mampu memperkuat hubungan transaksi non tunai terhadap jumlah uang beredar.

Kata Kunci: ATM debet. ATM kredit, uang eletronik, inflasi, jumlah uang beredar (M1)

ABSTRACT
The use of Non-cash transactions in society are increasing recently. It is more practical, easy and fast, moreover non-cash transactions have an influence on monetary policy in Indonesia. In monetary policy, non-cash transactions affect the level of money supply. In addition, there are other factors that can affect the money supply, namely inflation. Non-cash transactions in this study use a debit ATM, credit ATM and electronic money. The purpose of this study is to obtain evidence of the effect of non-cash transactions on the money supply in Indonesia with inflation as a moderating variable during 2015-2018. Data collection is based on secondary data and the analysis technique used is Moderating Regression Analysis (MRA) test. This research results that non-cash transactions have a positive and significant effect on the money supply and inflation is able to strengthen the relationship of non-cash transactions and the money supply.
Keywords: Debit AT, ATM credit, electronic money, inflation, money supply (M1)
PENGARUH KEPUTUSAN INVESTASI, KEPUTUSAN PENDANAAN, KEBIJAKAN DIVIDEN, DAN UKURAN DEWAN KOMISARIS TERHADAP NILAI PERUSAHAAN PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BURSA EFEK INDONESIA PERIODE 2016-2018
Authors: Gatot Nazir Ahmad  , Rizal Lullah  , M. Edo S. Siregar  
Published: February 2021

Penelitian ini bertujuan untuk mengetahui Pengaruh Keputusan Investasi, Keputusan Pendanaan, Kebijakan Dividen, dan Ukuran Dewan Komisaris Terhadap Nilai Perusahaan pada Perusahaan Manufaktur yang Terdaptar Di Bursa Efek Indonesia Periode 2016-2018. Variabel bebas yang digunakan pada penelitian ini adalah Keputusan Investasi (PER), Keputusan Pendanaan (DER), Kebijakan Dividen (DPR), dan Ukuran Dewan Komisaris. Variabel terikat yang digunakan adalah Nilai Perusahaan (PBV). Metode pengambilan sampel yang digunakan dalam penelitian ini menggunakan teknik Purposive Sampling, dan diperoleh jumlah sampel sebanyak 70 perusahaan. Teknik analisis yang digunakan dalam penelitian ini adalah regresi data panel. Hasil penelitian ini menunjukan bahwa Keputusan Ivestasi dengan proksi PER berpengaruh signifikan positif terhadap Nilai Perusahaan, Keputusan Pedanaan dengan proksi DER tidak berpengaruh signifikan negatif terhadap Nilai Perusahaan, Kebijakan Dividen dengan proksi DPR tidak berpengaruh signifikan negatif terhadap Nilai Perusahaan, dan Ukuran Dewan Komisaris berpengaruh signifikan positif terhadap Nilai Perusahaan (PBV).
The Relationship Between Emotional Intelligence and Cyberbullying Behavior in Adolescents in Salatiga
Authors: Sting Nataliinn 
Published: February 2021

This study is conducted to examine the correlation between emotional intelligence and cyberbullying behaviour among teenagers in Salatiga. It involved 405 teenagers aged 15-17 years old (247 girls and 158 boys). Data were taken using The Assessing Emotion Scale of Schutte, Malouff, dan Bhullar (2009), consisted of 33 items with validity coefficient 0,843, to examine validity coefficient, and The Cyber-Bullying Questionnaire of Esther Calvete, Izaskun Orue, Ana Estévez, Lourdes Villardón, and Patricia Padilla (2010), consisted of 16 items with validity 0,839, to examine the variable of the behaviour. It was analyzed using Spearman's rank correlation coefficient in SPSS 16.0 for windows. The results showed a significant negative correlation between emotional intelligence and cyberbullying behaviour with rxy = -0,126 dan p = 0,006 (p < 0,05).
High copy number variations, particular transcription factors, and low immunity contribute to the stemness of prostate cancer cells.
Authors: Dai Zao , Liu Ping 
Published: February 2021

Abstract
Background: Tumor metastasis is the main cause of death of cancer patients, and the existence of cancer stem cells is the basis of tumor metastasis. However, the systematic analysis of the stemness of prostate cancer cells is still not abundant. This article explores the effective factors that lead to the stemness of prostate cancer cells with multi-omics data mining.Methods: Gene expression modules that were strongly related to the stemness of prostate cancer cells were obtained with WGCNA and stemness scores, based on the prostate cancer transcriptome data in TCGA. Calculated the copy number variation of stemness genes of prostate cancer and evaluated the difference of transcription factors in prostate cancer and normal tissues, based on CNV (copy number variation) data and ATAC-seq data. The protein interaction network of stemness genes of prostate cancer was constructed with the STRING database. At the same time, the correlation between stemness genes of prostate cancer and immune cells was analyzed.Results: Prostate cancer with high Gleason grade was more stemness. The gene set highly related to prostate cancer stemness had higher CNV in prostate cancer samples than normal samples. The transcription factors of stemness genes had similar expressions but had different contributions in normal and prostate cancer tissues. And particular transcription factors enhanced the stemness of prostate cancer, such as PUM1, CLOCK, SP1, TCF12, and so on. The lower tumor immune microenvironment was conducive to the stemness of prostate cancer, and CD8+ T cells and M1 macrophages might play an important role than other immune cells in the tumor microenvironment. We also found that EZH2 played a central role in stemness genes and was negatively correlated with resting mast cells and positively correlated with activated memory CD4+ T cells.Conclusions: This study found that high copy number variation, specific transcription factors, and low immune microenvironment contributed to the stemness of prostate cancer cells through systematic multi-omics analysis. These findings would provide new clues and directions for future research of prostate cancer stem cells.
Genome-wide analysis identifies critical DNA methylations within NTRKs genes in colorectal cancer
Authors: Chen Zijian , Huang Zenghong , Luo Yanxin , Zou Qi , Bai Liangliang , Tang Guannan , Wang Xiaolin , Cao Guangwen , Huang Meijin , Xiang Jun , Yu Huichuan 
Published: February 2021

Abstract
Background: Neurotrophic tropomyosin receptor kinases (NTRKs) are a gene family function as oncogene or tumor suppressor gene in distinct cancers. We aimed to investigate the methylation and expression profiles and prognostic value of NTRKs gene in colorectal cancer (CRC).Methods: An analysis of DNA methylation and expression profiles in CRC patients was performed to explore the critical methylations within NTRKs genes. The methylation marker was validated in a retrospectively collected cohort of 229 CRC patients and tested in other tumor types from TCGA. DNA methylation status was determined by quantitative methylation-specific PCR (QMSP).Results: The profiles in six CRC cohorts showed that NTRKs gene promoter was more frequently methylated in CRC compared to normal mucosa, which was associated with suppressed gene expression. We identified a specific methylated region within NTRK3 promoter targeted by cg27034819 and cg11525479 that best predicted survival outcome in CRC. NTRK3 promoter methylation showed independently predictive value for survival outcome in the validation cohort (P = 0.004, HR = 2.688, 95% CI = [1.355, 5.333]). Based on this, a nomogram predicting survival outcome was developed with a C-index of 0.705. Furthermore, the addition of NTRK3 promoter methylation improved the performance of currently-used prognostic model (AIC: 516.49 vs 513.91; LR: 39.06 vs 43.64, P = 0.032). Finally, NTRK3 promoter methylation also predicted survival in other tumors, including pancreatic cancer, glioblastoma and stomach adenocarcinoma.Conclusions: This study highlights the essential value of NTRK3 methylation in prognostic evaluation and the potential to improve current prognostic models in CRC and other tumors.
Detection of SARS-CoV-2-specific antibodies via rapid diagnostic immunoassays in COVID-19 patients
Authors: Chansaenroj Jira , Yorsaeng Ritthideach , Posuwan Nawarat , Puenpa Jiratchaya , Sudhinaraset Natthinee , Chirathaworn Chintana , Poovorawan Yong 
Published: February 2021

Abstract
Background: Efficient monitoring and control of coronavirus disease 2019 (COVID-19) require access to diagnostic tests, and serological diagnostic testing is desirable. In the current study, antibodies were investigated in patients recently diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.Methods: Cross-sectional data were obtained from 245 patients in whom SARS-CoV-2 infection had been confirmed via real-time reverse transcriptase-polymerase chain reaction between March and October 2020. Serum samples were acquired between 2 and 60 days following the onset of COVID-19 symptoms or the first detection of SARS-CoV-2 in asymptomatic patients. All specimens were tested simultaneously using an IgM/IgG rapid diagnostic test (RDT), IgG nucleocapsid protein-based chemiluminescent microparticle immunoassay (CMIA), IgG, and IgA spike protein-based enzyme-linked immunosorbent assays (ELISAs). Blood donor samples obtained in 2018 were used as negative controls. Results: The sensitivity and specificity of the RDT IgG were compared with the IgG immunoassays as standards. The RDT IgG exhibited 97.5% sensitivity and 89.4% specificity compared with a CMIA IgG, 98.4% sensitivity, and 78.8% specificity compared with an ELISA IgG. IgM, IgG, and IgA seropositivity rates were low between 1-2 weeks after COVID-19 symptom onset or the detection of SARS-CoV-2 RNA. IgM seropositivity rate began decreasing after 4 weeks, whereas IgG and IgA seropositivity rate remained at appreciable levels over the 8-week study period. No cross-reactivity with seasonal coronaviruses was detected.Conclusions: IgM/IgG RDTs alone or combined with molecular diagnostic tests may be useful for identifying recent SARS-CoV-2 infection.
Effect of denosumab switched from bisphosphonates in preventing joint destruction in postmenopausal rheumatoid arthritis patients with anti-cyclic citrullinated peptide antibodies
Authors: Mori Yu , Izumiyama Takuya , Kurishima Hiroaki , Kamimura Masayuki , Baba Kazuyoshi , Mori Naoko , Itoi Eiji 
Published: February 2021

Abstract
Introduction: This study aimed to determine the effects of denosumab treatment on the joint destruction of Japanese females with rheumatoid arthritis (RA) and anti-cyclic citrullinated peptide (CCP) antibodies. Materials and Methods: This retrospective longitudinal study included 56 patients treated with denosumab and 50 patients treated with bisphosphonate. All participants were positive for anti-CCP antibodies. All patients also had a history of osteoporosis treatment with bisphosphonate, which was either continued or switched to 60 mg of subcutaneous denosumab injection every 6 months. To assess the progression of joint destruction, hand and foot radiographs were taken, and changes in modified total Sharp score (mTSS), erosion score (ERO) and joint space narrowing score (JSN) were evaluated at 12 months and 24 months. The changes in BMD of the lumbar spine and hip were also assessed at 12 months. Results: At 12 months, there were significant differences in the change of ERO (p = 0.015) and mTSS (p = 0.01). Similarly, there were significant differences in the change of ERO (p = 0.013) and mTSS (p = 0.003) at 24 months. In contrast, no significant difference was observed in the changes of JSN and clinical parameters. There were significant differences in the changes in BMD in the femoral neck (p = 0.011) and total hip (p = 0.012).Conclusion: Denosumab treatment might be effective for the inhibition of bone erosion progression in the patients with RA, and it potentially contributes to the treatment of osteoporosis and prevention of destructive arthritis in patients with switching treatment from bisphosphonate.
Synthesis, antibiotic structure-activity-relationships, and cellulose dissolution studies of new room-temperature ionic liquids derived from lignin
Authors: Liu Shihong , Gonzalez Michael , Kong Celine , Weir Scott , Socha Aaron 
Published: February 2021

Abstract
Background: Ionic liquids (ILs) are promising pretreatment solvents for lignocellulosic biomass, but are largely prepared from petroleum precursors. Benzaldehydes from depolymerized lignin, such as vanillin, syringaldehyde, and 4-methoxy benzaldehyde, represent renewable feedstocks for the synthesis of ionic liquids. We herein report syntheses of novel lignin-derived ionic liquids, with extended N-alkyl chains, and examine their melting points, cellulose dissolution capacities, and toxicity profiles against Daphnia magna and E. coli strain 1A1. The latter organism has been engineered to produce isoprenol, a drop-in biofuel and precursor for commodity chemicals. Results: The new N,N-diethyl and N,N-dipropyl methyl benzylammonium ILs were liquids at room temperature, showing 75-100oC decreased melting points as compared to their N,N,N-trimethyl benzylammonium analog. Extension of N-alkyl chains also increased antibacterial activity 3-fold, while ionic liquids prepared from vanillin showed 2- to 4-fold lower toxicity as compared to those prepared from syringaldehyde and 4-methoxybenzaldehyde. The trend of antibacterial activity for anions of lignin-derived ILs was found to be methanesulfonate < acetate < hydroxide. Microcrystalline cellulose dissolution, from 2-4 wt% after 20 min at 100oC, was observed in all new ILs using light microscopy and IR spectroscopy.Conclusions: Ionic liquids prepared from H-, S- and G-lignin oxidation products provided differential cytotoxic activity against E.coli and D. magna, suggesting these compounds could be tailored for application specificity within a biorefinery.
Electron Spin Resonance of Single Molecules and Magnetic Interaction through Ligands
Authors: Zhang Xue , Wolf Christoph , Wang Yu , Aubin Hervé , Bilgeri Tobias , Willke Philip , Heinrich Andreas , Choi Taeyoung 
Published: February 2021

Abstract
Electron spin resonance (ESR) spectroscopy is a crucial tool to determine the chemical structure of materials. ESR spectra measured in molecular systems, however, are established on large ensembles of spins and usually require complicated structural analysis. Recently, scanning tunneling microscopy (STM) combined with ESR has been proven as a powerful tool to image and coherently control individual atomic spins on surfaces. Here, we extend this technique to demonstrate ESR on single organic molecules - iron phthalocyanine (FePc) - and investigate the magnetic interactions between a molecular spin and either another molecular or atomic spin. We show that the molecular spin density is not only localized at the central Fe atom, but also distributed to the outer ligands, yielding a strongly anisotropic exchange coupling. Our work opens the door for using molecules in nanoscale ESR studies and promises tuning magnetic interactions between non-localized spins via tailoring ligand field symmetry and strength.