bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of the Paternal Brain in Humans throughout Pregnancy
Authors: Diaz-Rojas Françoise , Matsunaga Michiko , Tanaka Yukari , Kikusui Takefumi , Mogi Kazutaka , Nagasawa Miho , Asano Kohei , Abe Nobuhito , Myowa Masako 
Published: November 2021

Abstract
Previous studies have demonstrated that paternal caregiving behaviours are reliant on neural pathways similar to those supporting maternal care. Interestingly, a greater variability exists in parental phenotypes in males than in females among individuals and mammalian species. However, less is known about when or how such variability emerges in human males. We investigated the longitudinal changes in the neural, hormonal and psychological bases of expression of paternal caregiving in humans throughout pregnancy and the first four months postpartum. We measured oxytocin and testosterone, paternity-related psychological traits and neural response to infant-interaction videos using fMRI in first-time fathers and childless men at three time points (early–mid-pregnancy, late-pregnancy and postpartum). We found that paternal-specific brain activity in prefrontal areas distinctly develops during middle-to-late pregnancy and is enhanced postpartum. Additionally, among fathers, the timing of the development of prefrontal brain activity was associated with specific parenting phenotypes.
Exploring the Clinical Characteristics of the Lymph Nodal Metastatic Regions in Patients with Endometrial Cancer
Authors: Shin Wonkyo , Kim Sun-Young , Park Sangyoon , Kang Sokbom , Lim Myong Cheol , Seo Sang-Soo 
Published: November 2021

Abstract
Objective

To evaluate clinical factors that can help determine the extent of lymphadenectomy required in endometrial cancer patients and confirm the differences of metastatic lymph node regions based on the risk factors for endometrial cancer patients.
Methods

The medical records of 468 endometrial cancer patients were retrospectively reviewed between January 2006 and December 2018. Patients were categorized into pelvic lymph node dissection (PLND) and pelvic plus para-aortic lymph nodes dissection (PPALND) groups. Demographics, recurrence-free survival, and 5-year overall survival rates were compared, and the clinical factors affecting survival were evaluated using Cox proportional hazards model.
Results

The median follow-up period was 55 months (range, 6–142 months). The mean age was higher in the PPALND group than in the PLND group (51.0 vs. 54.5 years; P < 0.001). The PPALND group had a higher International Federation of Gynecology and Obstetrics (FIGO) stage, lymphovascular invasion, endocervical invasion, and FIGO grade (P = 0.001) than the PLND group. The PPALND group had higher 5-year recurrence-free and overall survival rates than the PLND group. While comparing lymph node (LN) metastasis confirmed pathologically, the group with confirmed metastasis showed a higher number of high-risk group patients than lymph node-negative patients. However, no difference was observed in pelvic LN metastasis, pelvic plus para-aortic LN metastasis, and isolated para-aortic LN metastasis groups.
Conclusions

When treating patients with endometrial cancer, risk group evaluation is an important factor for determining LN dissection. Our study found no differences in clinical factors of metastatic LN regions.
Broiler Behaviour Differs From Males to Females When Under Different Light Wavelengths
Authors: Paixão Sandro José , Mendes Angélica Signor , Possenti Marco Antonio , Sikorski Rosana Reffatti , Vale Marcos Martinez do , de Souza Cleverson , Guimarães Bruno Evangelista , de Moura Daniella Jorge , Nääs Irenilza de Alencar , Nunes Isadora Bischoff 
Published: November 2021

Abstract
It is well established that different light wavelengths affect broiler behavior. The present study aims to evaluate the effect of four light wavelengths on broiler behavior from 1 to 42-days of age. Birds were housed at a stocking density of 13 birds/m2, in 32 boxes of 1.56 m2. The experimental design was a completely randomized factorial of 4x2 (four colors x two sexes), with four replicates. Behavioral variables were accessed through cameras and observed in person thrice a week for 30 min per day in three different periods. Data was organized according to age groups and analyzed by data mining approach with the different light wavelengths as the classes. Natural behavior of male broilers reared in environments with green. Blue light was more relevant to the classification of male broilers behavior (96.9 and 96.9% accuracy and 0.8 and 1.0 of class precision of behavior classification, respectively). Blue and green lights affected the behavior of male broilers starting at 7-days of age, increasing the presence at the bird feeder, and reducing the idle period.
Media and History: Discourse of Historical Responsibility in a Changing World
Authors: Буллер А. , Линченко А.А. 
Published: November 2021

В статье проанализированы особенности трансформации аксиологических функций медиа в отношении общественных представлений о прошлом в контексте антагонистического, космополитического и агонического проектов коллективной памяти. Обосновывается мысль, что переход от антагонистического к космополитическому типу коллективных воспоминаний в прошлом столетии и обозначившийся в начале XXI в. поворот к элементам агонического типа способствуют трансформации функций медиа и повышению их аксиологического статуса как среды развертывания дискурса исторической ответственности. Это связано с усилением роли и значения медиа в качестве инструмента конструирования самого дискурса исторической ответственности, а также инструмента демаркации различных ценностных сред обращения к прошлому и их носителей – сообществ памяти.
The article deals with actual problems of the transformation of the axiological functions of media in relation to public representations of the past in the context of antagonistic, cosmopolitan and agonistic projects of collective memory. The transition from the antagonistic to the cosmopolitan type of collective memories in the last century and the turn towards elements of the agonistic type that has emerged today contribute to the transformation of media functions. This transformation is associated with the strengthening not so much of their epistemological status as their axiological status in relation to the past. The axiological status of media is associated with understanding it as a significant environment for the deployment of the discourse of historical responsibility. Modern media act as a tool for constructing the very discourse of historical responsibility, as well as a tool for demarcating various value environments of referring to the past and their carriers - communities of memory.
The British Jingo and the German Viking: the Emergence and Reception of the Colonial Hero Image of Cecil Rhodes and Carl Peters
Authors: Турыгин А.А. , Зимина Е.В. 
Published: November 2021

Литература, наряду с официальными источниками, может дать представление о формировании культа двух одиозных деятелей колониальной эпохи – Сесила Родса и Карла Петерса. Их деятельность на африканском континенте, получившая неоднозначную оценку при жизни, впоследствии была переосмыслена официальной пропагандой, привела к изменению общественного мнения о колониализме и имперских ценностях. Африканское прошлое Империи в Великобритании вылилось в одну из форм протеста 2020 г., в то время как в Германии его пересмотр был связан с оценками национал-социализма, реанимировавшего идеи колониализма.
The paper considers the colonial policy of Kaiser Germany and the British Empire in Africa via periodicals and fiction. Alongside with official sources, fiction can provide an insight into the way the cult of the two most notorious colonialists – Cecil John Rhodes and Carl Peters – emerged. Their activities in the African continent, cautiously assessed even in their lifetime, was reconsidered in official propaganda and by writers of the 19th-20th centuries, which led to the change in public opinion regarding colonialism and imperial values. The process of reconsidering went in different ways, however. The imperial past of the British Empire was shown in the protests of 2020 in the UK, whereas in Germany this reconsideration is closely connected with the reassessment of the Nazi period that attempted to revive colonial ideas of the first quarter of the 20th century.
"I am at your disposal": a letter from Karl Lamprecht to Nikolai Kareev, 1914
Authors: Долгова Е.А. , Дмитриева Н.А. , Штольценберг Ю. 
Published: November 2021

В публикации реконструируется малоизвестная часть биографии Н.И. Кареева (1850–1931), связанная с пятинедельным пребыванием на территории Германии в на-чале Первой мировой войны. В центре публикации – письмо К. Лампрехта Н.И. Карееву, написанное в июле 1914 г. и выявленное в Научно-исследовательском отделе рукописей РГБ. Поводом к написанию письма для Н.И. Кареева стало обращение за помощью в содействии/протекции по вопросу возвращения на родину. Письмо вносит дополнительные ноты в изучение роли личных контактов ученых. Публикуется оригинал письма и перевод текста с немецкого языка.
This article reconstructs a little-known part of the biography of Nikolay I. Kareev (1850-1931), associated with a five-week stay in Germany at the beginning of the First World War.. In the center of the publication is a letter from Karl Lamprecht to Nikolay Kareev, written in July 1914 and identified in the Research Department of Manuscripts of the Russian State Library. The reason for writing a letter to Kareev was to ask for help in promoting / protecting the issue of returning to the homeland. The letter adds additional notes to the study of the role of personal contacts of scientists and should be taken into account when reconstructing the scientific biography of Russian and German professors. The original letter and the translation of the text from the German language are published.
“We are familiar with your level of competence in historiography” The correspondence from Henri See to Nikolay Kareev in 1930-1931
Authors: Слискова В.В. 
Published: November 2021

В статье рассматривается переписка Николая Ивановича Кареева с французским историком Анри Сэ, материалы которой отложились в Научно-исследовательском отделе рукописей Российской государственной библиотеки. Они представляют собой письма, полученные Н.И. Кареевым от А. Сэ в 1930–1931 гг., в которых обсуждалась подготовка одной из его последних работ – статьи для французского научного издания «Revue d’histoire moderne».
The article deals with the epistolary materials of Russian historian Nikolay Kareev which were found in the Manuscript Department of the Russian State Library. Materials consist of the letters that N. Kareev received from French historian Henri Sée in 1930-1931. Historians discussed the preparation of N. Kareev’s last article which was specially written for the “Revue d’histoire moderne” in 1930. The letters complement the part of N. Kareev’s scientific biography concerning his scientific contacts with French historians and his publishing activity in 1930-1931. The documents were found in the Manuscript Department of the Russian State Library and prepared for publication by V.V. Sliskova.
Obedience to the law – more than bondage: Grand Duchy of Finland in Confrontation with the Russian Empire
Authors: Экштут С.А. 
Published: November 2021

Рецензия на сборник документов «Россия и независимость Финляндии: 1899–1920 гг.» (М.: «Политическая энциклопедия», 2021). В трех томах опубликовано 1358 документов (более 42% предстают перед читателем впервые) из ГА РФ, РГИА, РГАСПИ, РГАЭ, РГАВМФ, РГВА, из архивов МИДа ‒ АВПРИ и АВП РФ, Архива Президента Российской Федерации и Национального архива Финляндии.
The article presents f review of the collection of documents "Russia and the independence of Finland: 1899-1920." (Moscow: "Political Encyclopedia", 2021). In three volumes, 1358 documents were published (more than 42% appear before the reader for the first time) from the State Archives of the Russian Federation, RGIA, RGASPI, RGAE, RGAVMF, RGVA, from the archives of the Ministry of Foreign Affairs - AVPRI and AVP RF, Archive of the President of the Russian Federation and the National Archives of Finland.
Evaluation of service pressure regulation strategy on the performance of a rural water network based on pulse demand; using the method of characteristics
Authors: Negharchi Saeid Mohammadzade , Shafaghat Rouzbeh 
Published: November 2021

Abstract
Reducing the occurrence of pipe bursts, reducing leakage, and reducing energy consumption are the three main goals in implementing pressure control programs in water distribution networks. Service pressure regulation strategy is an evolved approach that encompasses all goals of pressure management. This paper has investigated this approach in a rural network with hydraulic complexities as a case study so that some parts of the network have excess pressure and other low pressure. A computer code based on the method of characteristics (MOC) has been developed for network hydraulic analysis. The generated code analyzes unsteady flow, pressure-driven demand analysis, and dynamic adjustment of pressure control valves based on the target node. Also, the experimental results of a laboratory network have been applied to validate and calibrate the numerical simulation. In addition, by measuring the flow rate and pressure of the network and the results of the minimum night flow method, three consumption patterns were used to generate pulsed nodal demands. Studies show that creating pressure-management areas by hydraulic analysis by MOC will determine the best control strategies. The mean pressure decreased 54% by applying this strategy. Furthermore, the average fluctuations of pressure reduced from 9.7 meters to 3.5 meters.
Rhodamine-B dye removal using aliquat-336 modified amberlite XAD-4 resin in fixed-bed columns in series
Authors: Iqbal Muzaffar , Datta Dipaloy 
Published: November 2021

Abstract
The present work reports studies on the effective removal of Rhodamine-B (RhB) using Aliquat-336 modified Amberlite XAD-4 resin in the fixed-bed columns in series. The effect of flow rate (Q = 2 to 6 mL·min−1), bed height (h = 3.5 to 7 cm) and initial RhB dye concentration (Cin = 10 to 20 mg·L−1) was studied. When a single column was used, 93% RhB dye was removed in 3 h at Q= 2 mL·min−1, Cin = 10 mg·L−1, and h = 7 cm. When three columns in series were used, almost 100% dye was removed until 80 h. The maximum breakthrough time (142 h) and saturation time (244 h) were found by keeping Q= 2 mL·min−1, h = 7 cm of each column and Cin = 10 mg·L−1. Mathematical modeling of the breakthrough curves was done by using Yoon-Nelson, Clark, Wolborska, and pore diffusion models. The Clark model best fitted the experimental data. The possible interaction mechanism between Aliquat-336 and RhB dye was proposed. The column was regenerated in continuous mode using 1 M HCl solution and maintaining a flow rate of 2 mL·min−1.
Investigation on the performance evaluation of vertical subsurface flow constructed wetland for the treatment of rural wastewater
Authors: Shruthi R. , Shivashankara G. P. 
Published: November 2021

Abstract
In a rural country like India, low cost and decentralized treatment units like the vertical subsurface flow constructed wetland (VSSF CW) can be reflected as a novel wastewater system. In this concern, a pilot-scale VSSF CW unit of size 0.92 m × 0.92 m × 0.85 m bed planted with Typha latifolia and Phragmites australis was operated for a 12-month duration to treat simulated rural wastewater. During the operation, a constant head arrangement was made to maintain a continuous flow to achieve 5 different Hydraulic Retention Times (HRTs) of 2, 4, 6, 8 and 10 days in each season, such as winter, summer and rainy, to investigate the performance of the unit under different retention times. The reactor showed optimum removal efficiency at 6 days HRT at 12.5 cm/day Hydraulic Loading Rate (HLR) for organic matter removal. Both macrophytes and the microbial biomass of filter media effectively treated the rural wastewater. Average removal efficiency of the reactor during the entire study was 64.73%–88.80% for Chemical Oxygen Demand, 74.96%–95.34% for Biochemical Oxygen Demand, 40.13%–79.45% for Ammonia Nitrogen, 25.36%–65.65% for Total Kjeldahl Nitrogen, 22.86%–58.48% for Phosphate phosphorus, 23.50%–55.45% for Total phosphorous, 74.91%–98.59% for Faecal Coliforms and 71.14%–95.31% for Total Coliforms respectively. Two-way ANOVA followed by post-hoc Tukey's test showed that HRT had a significant impact on removal efficiency but not the season. Overall performance of the unit was good and study suggested that VSSF CW can be a smart alternative technology to treat rural wastewater before final disposal.
Interplay Between Endocannabinoid System and Neurodegeneration:
Focus on Polypharmacology
Authors: Seghetti Francesca , Gobbi Silvia , Belluti Federica , Rampa Angela , Bisi Alessandra 
Published: November 2021

:
Pharmacological treatment of complex pathologies, such as neurodegenerative
diseases still represents a major challenge, due to the networked pathways involved in
their onset and progression that may require equally complex therapeutic approaches.
Polypharmacology, based on the simultaneous modulation of multiple targets involved in
the disease, may offer the potential to increase effectiveness and reduce the drawbacks related
to the use of drug combinations. Clearly, this approach requires both the knowledge
of the systems responsible for disease development and the discovery of new attractive
targets to be exploited to design a multitarget drug. Over the last years, an ever increasing
interest has focused on the endocannabinoid system, implicated in the modulation of several
physiological functions, among which neuroinflammation, a crucial process for most
neurodegenerative diseases. In this respect, the cannabinoid receptor subtype 2 represents
a promising therapeutic target, being overexpressed in microglia cells and thus involved
in neuroinflammation. The indirect modulation of this system through the inhibition of
the main enzymes responsible for endocannabinoids metabolism, namely fatty acid amide
hydrolase and monoacylglycerol lipase, may also significantly affect neurodegenerative
processes. The aim of this review is to give an overview of the opportunities posed by the
endocannabinoid system for neurodegenerative diseases management, mainly focusing on
the potential for a multitarget strategy.
Effectiveness of a Mobile Device–Based Resilience Training Program in Reducing Depressive Symptoms and Enhancing Resilience and Quality of Life in Parents of Children With Cancer: Randomized Controlled Trial
Authors: Luo Yuanhui , Xia Wei , Cheung Ankie Tan , Ho Laurie Long Kwan , Zhang Jingping , Xie Jianhui , Xiao Pin , Li Ho Cheung William 
Published: November 2021

Background
Caring for children with cancer can be a stressful experience for parents and may have negative effects on their physical and psychological well-being. Although evidence has shown that resilience is associated with positive psychological well-being, few interventions have been specifically designed to enhance the resilience of parents of children with cancer.

Objective
The aim of this study is to examine the effectiveness of a mobile device–based resilience training program in reducing depressive symptoms and enhancing resilience and quality of life (QoL) in parents of children with cancer.

Methods
Parents of children diagnosed with cancer were recruited from the pediatric oncology wards of 3 tertiary hospitals in China. The participants were randomly assigned to either the experimental group (52/103, 50.5%) to undergo an 8-week mobile device–based resilience training program or to the control group (51/103, 49.5%) to receive an 8-week program of placebo information. The study outcomes included resilience, depressive symptoms, and QoL, as measured by the Connor–Davidson Resilience Scale, the Self-Rating Depression Scale, and the Short Form of the 6-Dimension Health Survey, respectively. All data were collected at baseline and at 2 and 6 months of follow-up. The data analysis followed the intention-to-treat principle. A generalized estimating equation was used to examine the effects of the intervention.

Results
The participants were mostly female (72/103, 69.9%), and their mean age was 33.6 (SD 5.2) years. The participants in the experimental group showed significantly higher levels of resilience (mean 67.96, SD 15.8 vs mean 58.27, SD 19.0; P<.001) and lower levels of depressive symptoms (mean 40.17, SD 9.9 vs mean 46.04, SD 10.9; P<.001) than those in the control group at 6 months of follow-up. The intervention showed statistically significant effects in improving resilience (β=6.082; P=.01) and decreasing depressive symptoms (β=−2.772; P=.04) relative to the control group. The QoL score in the experimental group was higher than that in the control group at 6 months of follow-up (mean 0.79, SD 0.2 vs mean 0.76, SD 0.3; P=.07); however, no statistically significant intervention effect was detected (β=.020; P=.38).

Conclusions
The mobile device–based resilience training program effectively enhanced resilience and alleviated depressive symptoms in parents of children with cancer. It is highly recommended that health care professionals incorporate this resilience training program when providing psychological care to parents of children with cancer.

Trial Registration
Clinical.Trials.gov NCT04038242; http://clinicaltrials.gov/ct2/show/NCT04038242
A Pipeline to Understand Emerging Illness Via Social Media Data Analysis: Case Study on Breast Implant Illness
Authors: Dey Vishal , Krasniak Peter , Nguyen Minh , Lee Clara , Ning Xia 
Published: November 2021

Background
A new illness can come to public attention through social media before it is medically defined, formally documented, or systematically studied. One example is a condition known as breast implant illness (BII), which has been extensively discussed on social media, although it is vaguely defined in the medical literature.

Objective
The objective of this study is to construct a data analysis pipeline to understand emerging illnesses using social media data and to apply the pipeline to understand the key attributes of BII.

Methods
We constructed a pipeline of social media data analysis using natural language processing and topic modeling. Mentions related to signs, symptoms, diseases, disorders, and medical procedures were extracted from social media data using the clinical Text Analysis and Knowledge Extraction System. We mapped the mentions to standard medical concepts and then summarized these mapped concepts as topics using latent Dirichlet allocation. Finally, we applied this pipeline to understand BII from several BII-dedicated social media sites.

Results
Our pipeline identified topics related to toxicity, cancer, and mental health issues that were highly associated with BII. Our pipeline also showed that cancers, autoimmune disorders, and mental health problems were emerging concerns associated with breast implants, based on social media discussions. Furthermore, the pipeline identified mentions such as rupture, infection, pain, and fatigue as common self-reported issues among the public, as well as concerns about toxicity from silicone implants.

Conclusions
Our study could inspire future studies on the suggested symptoms and factors of BII. Our study provides the first analysis and derived knowledge of BII from social media using natural language processing techniques and demonstrates the potential of using social media information to better understand similar emerging illnesses.