bluuebunny/crossref_metadata_2025_split huggingface dataset:
Zinconigerite-2N1S ZnSn2Al12O22(OH)2 and zinconigerite-6N6S Zn3Sn2Al16O30(OH)2, two new minerals of the nolanite-spinel polysomatic series from the Xianghualing skarn, Hunan Province, China
Authors: Rao Can , Gu Xiangping , Wang Rucheng , Xia Qunke , Dong Chuanwan , Hatert Frédéric , Bo Fabrice Dal , Yu Xuege , Wang Wumengyu 
Published: November 2021

Abstract
Zinconigerite-2N1S ZnSn2Al12O22(OH)2 and zinconigerite-6N6S Zn3Sn2Al16O30(OH)2 are two new minerals with different numbers and ratios of nolanite (N) and spinel (S) modules. Both phases have been discovered in the Xianghualing skarn, Hunan Province, China. Zinconigerite-2N1S (zn-2N1S) and zinconigerite-6N6S (zn-6N6S) are named for their chemical composition, number, and ratios of N-S modules, according to the nomenclature of the nolanite-spinel polysomatic series of Armbruster (2002). Both phases occur as aggregates, sub-to-euhedral crystals, with maximal dimensions up to 100 μm, within fluorite aggregates, and they are closely associated with phlogopite, chrysoberyl, magnetite, cassiterite, margarite, and nigerite-taaffeite group minerals. They do not show fluorescence in long- or short-wave ultraviolet light. The calculated densities are 4.456 g/cm3 for zn-2N1S and 4.438 g/cm3 for zn-6N6S. Optically, zn-2N1S is uniaxial (+) with ω = 1.83(1), ε = 1.84(2); zn-6N6S is uniaxial (+) with ω = 1.85(1), ε = 1.87(2) (λ = 589 nm). Their chemical compositions by electron-microprobe analyses give the empirical formulas (Zn0.734Mn0.204Na0.122Ca0.063Mg0.044)Σ1.166(Sn1.941Zn0.053Ti0.007)Σ2 (Al11.018Fe0.6903+Zn0.200Si0.092)12O22(OH)2 for zn-2N1S and (Zn1.689Mn0.576Mg0.328Fe0.4073+)Σ3(Sn1.882Zn0.047 Ti0.071)Σ2(Al14.675Fe1.0883+Na0.13Ca0.086Si0.017)Σ15.996O30(OH)2 for zn-6N6S. Both phases have trigonal symmetry; the unit-cell parameters of zn-2N1S (P3m1) and zn-6N6S (R3m), refined from single-crystal X-ray diffraction data, are, a = 5.7191(2) and 5.7241(2) Å, c = 13.8380(6) and 55.5393(16) Å, V = 391.98(3) and 1575.96(12) Å3, and Z = 1 and 3, respectively. The structure of zn-2N1S is characterized by the alternating O-T1-O-T2-O-T1 layers stacked along the c-axis, showing the connectivity of N-S-N. The polyhedral stacking sequence of zn-6N6S is 3 × (O-T1-O-T2-O-T2-O-T1), reflecting a N-S-S-N-N-S-S-N-N-S-S-N connectivity of the polysomatic structure. By contrast, the structure of zn-2N1S shows the elemental replacements of Al → Sn and Al → Zn, suggesting the substitution mechanism of 2Al → Zn + Sn. The complex substitution of Zn by multiple elements (Al, Fe3+, Mn, Mg) in the structure of zn-6N6S, is coupled with the low occupancy of Al5-octahedra. Fe3+ → Al substitution occurs in Al1-tetrahedra of both zn-2N1S and zn-6N6S. The new polysomes, zn-2N1S and zn-6N6S, likely crystallized under F-rich conditions during the late stages of the Xianghualing skarn formation. The discovery of zn-2N1S and zn-6N6S provides new insights into the crystal chemistry of the N-S poly-somatic series and its origin.
Tracing structural relicts of the ikaite-to-calcite transformation in cryogenic cave glendonite
Authors: Németh Péter , Töchterle Paul , Dublyansky Yuri , Stalder Roland , Molnár Zsombor , Klébert Szilvia , Spötl Christoph 
Published: November 2021

Abstract
Ikaite is a calcium carbonate hexahydrate that forms at temperatures close to the freezing point of water; thus, its occurrence is associated with cryogenic conditions. This mineral is metastable and quickly transforms to calcite at temperatures above 5 °C. Pseudomorphs of calcite after ikaite are known as glendonite. The nanostructure of 25 000–43 000 year old glendonite from Victoria cave (Southern Ural, Russia) was investigated in search of structural features indicative of the ikaite-to-calcite transformation. Scanning electron microscope images display several micrometer- to submicrometer-size pores and indicate high intergranular porosity among the loosely aggregated grains. Transmission electron microscopy (TEM) data show evidence of 10–20 nm nanotwins [twin law (1014)] and 10–40 nm overlapping nanograins. Scanning TEM images reveal that the individual grains contain 5–10 nm long and 2–4 nm wide mesopores (sizes between 2 and 50 nm), which are aligned parallel to [1010] of calcite and might be associated with a crystallographically oriented dehydration of the precursor ikaite. Fourier transform infrared spectroscopy reveals no evidence of structural water but absorption bands related to molecular water trapped in fluid inclusions are present. Nitrogen absorption/desorption measurements show that the specific surface area of 5.78 m2/g and the pore volume of ~0.07 cm3/g for calcite, the constituent of glendonite, are comparable to those of a common natural calcite. We suggest that the aligned mesopores, frequently occurring twins, small grain size, presence of aqueous inclusions and the high micrometer- to submicrometer-size intergranular porosity arise from the ikaite-to-calcite transformation and thus may be used as criteria for the former presence of ikaite and hence for cold paleotemperatures. However, since similar features might also be common in biogenic carbonates, the diagnostic macroscopic pseudomorphs after ikaite are equally important for identifying glendonites and inferring cryogenic conditions.
Adsorption kinetics of reactive dye using agricultural waste: banana stem
Authors: Arun Kumar K. , Bharath M. , Krishna B. M. 
Published: November 2021

Abstract
Removal of color from dye-bearing water has been a bothering task from the health point of view and in the aesthetic sense as well. Finding out the effectiveness of Remazole Red RGB dye removal is the aim of the present work using banana stem, an agricultural waste, as an activated carbon. The preparation of the banana stem activated carbon was done in the laboratory by carbonization followed by activation. To assess the impact of varied exploratory variables such as pH of adsorbate, contact time, initial dye concentration and dosage of adsorbent on the removal of Remazole Red RGB dye from aqueous solution adopting batch studies were performed. The Freundlich and Langmuir isotherm models were used to predict the adsorption capacity of adsorbent at equilibrium conditions, the kinetic parameters were also determined. The concentration of dye remaining in the system was measured using a UV visible spectrometer. The batch test resulted in the removal of the maximum of 87% of dye when the dye concentration was 2 mg/L, at an adsorbent dose of 0.5 gm/L and dye pH 4 in 35 minutes. It is established from the studies that the equilibrium data suited excellently both Freundlich and Langmuir isotherms. The maximum adsorption capacity of 14.28 mg/L was established from the Langmuir isotherm model. To state the sorption kinetics, pseudo-first-order and pseudo-second-order kinetic models were evaluated. The intraparticle diffusion model was checked for the adsorption data and it was observed that intraparticle diffusion is not the only rate-limiting step. The regression analysis results indicated that the linear regression model gave the best results. The above detection exhibits that banana stems can be used productively for the removal of color from dye-containing wastewater.
ATUAÇÃO DOS RESIDENTES MULTIPROFISSIONAIS EM SAÚDE DA FAMÍLIA NA CAPACITAÇÃO DE AGENTES COMUNITÁRIOS DE SAÚDE: RELATO DE EXPERIÊNCIA
Authors: Jackson Gonçalves de Carvalho Daniel , Soares Oliveira Pâmela , Oliveira Silva Amanda , Carla Cordeiro Magali , Nogueira de Souza Thalyta , Custódio Neto Eliana , Cristina Gonçalves Leite Isabel 
Published: November 2021

Introdução: A Estratégia Saúde da Família (ESF) busca promover saúde de maneira integralizada, acessível e equânime dentro da Atenção Primária em Saúde. O agente comunitário de saúde(ACS) é uma categoria profissional essencial para a execução da ESF. Por esse motivo, é necessário a busca pela qualificação desta força de trabalho. Objetivo: O objetivo deste trabalho é retratar as atividades desenvolvidas durante a pandemia de Covid-19 com Agentes Comunitários de Saúde(ACS) em uma Unidade Básica de Saúde(UBS) em um município do estado de Minas Gerais. Metodologia: Trata-se de um relato de experiência oriundo de uma capacitação multiprofissional elaborada pelos Residentes Multiprofissionais em Saúde da Família(RMSF) realizada no período de Abril a Agosto de 2020. As oficinas eram apresentadas utilizando recursos manuais, audiovisuais e atividades mobilizadoras de participação, estimulando a interação desses profissionais e estreitando o vínculo entre o ACS e a equipe de saúde da família Resultados: As atividades eram realizadas a partir de oficinas mediante a discussão de temas relacionados ao cotidiano vivenciado pelos ACS na comunidade. Após a realização dessas atividades, notou-se os principais desafios enfrentados por essa categoria e sua relação com a equipe de saúde da família da UBS. Além disso, a atividade permitiu um espaço de reflexão sobre os impactos dessa interação entre equipe e ACS na comunidade. Conclusões: Portanto, conclui-se que esses encontros foram oportunos para enfatizar o seu protagonismo nessa lógica do processo de trabalho, destacando a busca pela qualificação desses profissionais, garantindo a integralidade do cuidado aos usuários.
PERFIL EPIDEMIOLÓGICO HIV/AIDS NO ESTADO DO PIAUÍ EM 2019
Authors: Gonçalves Costa Junior Ivanildo , Joana Serra Ribeiro Sara , Matheus Ferreira do Nascimento João , Soares Tiago , Nascimento Vieira Júnior Denival 
Published: November 2021

Introdução: O vírus da imunodeficiência Humana e a Síndrome da Imunodeficiência Adquirida ainda é expessivamente presente em grupos que sofrem de vulnerabilidades sociais, sendo um desafio ainda não superado, principalmente no que diz respeito ao desempenho de ações de saúde e por parte dos gestores no sentido da realização de prevenções amplas, baseadas nos contextos epidemiológicos das comunidades, cabendo também considerar os problemas de estrutura da rede de saúde para com o manejo diagnóstico, contextos de desigualdade e gênero que são as principais influencias para o desenvolvimento da doença. Objetivo: observar por meio de indicadores o panorama da situação do HIV/AIDS no Piauí no ano de 2019. Metodologia: Estudo epidemiológico realizado pela consulta às bases do DATASUS, IBGE e SINAN. Foram consultados dados referentes ao período de 2019, tendo como população avaliada a do Estado do Piauí. Buscou-se informações referentes aos indicadores de incidência, sexo, raça/cor, faixa etária, escolaridade e exposição, com foco nas taxas de incidência, óbitos e letalidade. Os dados foram agrupados e tabulados por meio dos programas Excel e Tabwin, utilizando o método de análise a técnica de percentagem. Resultados: No período vigente, o Estado apresentou 207 novos casos. A incidência foi de 6,32/100.000 habitantes, tendo maior detecção para o público masculino (73,91%), faixa etária de 30-39 anos, maior predominância da população parda, escolaridade de ensino médio completo e heterossexuais. Quanto a mortalidade, foram notificados 134 óbitos por HIV, predominante para o sexo masculino. A Letalidade mostrou que 65% foram realmente afetadas pela doença. Conclusões: O perfil epidemiológico dos casos de HIV/Aids no Piauí foi caracterizado pela prevalência em determinados grupos, demonstrando que apesar da existência de políticas públicas que buscam a prevenção da doença, essa realidade ainda é presente nos dias atuais. Ressalta-se a importância da realização de estudos epidemiológicos para comparação e analise situacionais futuras.
Palavras-Chave: Epidemiologia. HIV. Perfil de Impacto da Doença.
TNF-induced Lupus. A Case-Based Review
Authors: Skalkou Anastasia , Pelechas Eleftherios , Voulgari Paraskevi V. , Drosos Alexandros A. 
Published: November 2021

:Nowadays, tumor necrosis factor-alpha (TNFα) inhibitors have revolutionised the treatment of inflammatory arthritides by demonstrating efficacy with an acceptable toxicity profile. However, autoimmune phenomena and clinical entities have been reported ranging from an isolated presence of autoantibodies to full-blown autoimmune diseases, including drug-induced lupus (DIL).Case Presentation:A 62-year-old woman with rheumatoid arthritis (RA) refractory to methotrexate and prednisone was treated with adalimumab (ADA). 4 months later, she presented acute cutaneous eruptions after sun exposure, positive ANA (1/640 fine speckled pattern), Ro (SSA) and anti- Smith (Sm) antibodies with no other clinical or laboratory abnormalities. The diagnosis of DIL was made, ADA was discontinued, and she was treated successfully with prednisone plus local calcineurin inhibitors.Conclusion:Thus, we review the literature for cases of DIL development in patients treated with TNFα inhibitors. Rheumatologists should be aware of the possible adverse events and the requirement of careful clinical evaluation and monitoring.
Application of Some Graphene Derivatives to Increase the Efficiency of Stem Cell Therapy
Authors: Foroutan Tahereh 
Published: November 2021

Abstract:Graphene and its derivatives have application potential in many areas such as environmental technology, catalysis, biomedicine, and in particular, stem cell-based differentiation and regenerative therapies. Mesenchymal stem cell transplantation has emerged as a potential therapy for some diseases, such as acute kidney damage, liver failure and myocardial infarction. However, the poor survival of transplanted stem cells in such applications has significantly limited their therapeutic effectiveness. Graphene-based materials can improve the therapeutic efficacy of stem cells as they prevent the death of implanted cells by attaching them prior to implantation and increasing their paracrine secretion. In this review, we will highlight a number of recent studies that have investigated the potential use of graphene or its derivatives in stem cell applications and the prevention of transplanted stem cells from cell death, thereby improving their therapeutic efficacy.
Isopropyl Ricinoleate, A Potential Alternative to Isopropyl Myristate:
Experimental and Computational Evaluation
Authors: Pratap Amit , Mali Suraj N. , Khan Nishat , Meena P. , Mohile Rashmikant 
Published: November 2021

Background:
Due to growing environmental concerns, eco-friendly and sustainable materials have become one of the key interests of cosmetics research. Isopropyl myristate is be-ing used as a major cosmetic ingredient, like in many other cosmetic items, as an emollient for a long time.

Methods:
An emollient ester, isopropyl ricinoleate, is derived from non-edible oil, castor oil. The synthesized isopropyl ricinoleate using greener enzyme catalysed methodology was further tested for sensory evaluation and transepidermal water loss (TEWL) studies.

Results:
An ester, isopropyl ricinoleate, imparted better gloss and shine to the skin as compared to isopropyl myristate due to its higher refractive index. Both esters, isopropyl ricinoleate and isopropyl myristate, showed minimum tackiness and residue after spreading. Moreover, in-silico toxicity analysis of ester, isopropyl ricinoleate, supported previously reported in-vitro tox-icity data.

Conclusion:
Thus, the current study provides better insights on the replacement of emollient es-ter isopropyl myristate by isopropyl ricinoleate.
Natural Language Processing and Machine Learning Methods to Characterize Unstructured Patient-Reported Outcomes: Validation Study
Authors: Lu Zhaohua , Sim Jin-ah , Wang Jade X , Forrest Christopher B , Krull Kevin R , Srivastava Deokumar , Hudson Melissa M , Robison Leslie L , Baker Justin N , Huang I-Chan 
Published: November 2021

Background
Assessing patient-reported outcomes (PROs) through interviews or conversations during clinical encounters provides insightful information about survivorship.

Objective
This study aims to test the validity of natural language processing (NLP) and machine learning (ML) algorithms in identifying different attributes of pain interference and fatigue symptoms experienced by child and adolescent survivors of cancer versus the judgment by PRO content experts as the gold standard to validate NLP/ML algorithms.

Methods
This cross-sectional study focused on child and adolescent survivors of cancer, aged 8 to 17 years, and caregivers, from whom 391 meaning units in the pain interference domain and 423 in the fatigue domain were generated for analyses. Data were collected from the After Completion of Therapy Clinic at St. Jude Children’s Research Hospital. Experienced pain interference and fatigue symptoms were reported through in-depth interviews. After verbatim transcription, analyzable sentences (ie, meaning units) were semantically labeled by 2 content experts for each attribute (physical, cognitive, social, or unclassified). Two NLP/ML methods were used to extract and validate the semantic features: bidirectional encoder representations from transformers (BERT) and Word2vec plus one of the ML methods, the support vector machine or extreme gradient boosting. Receiver operating characteristic and precision-recall curves were used to evaluate the accuracy and validity of the NLP/ML methods.

Results
Compared with Word2vec/support vector machine and Word2vec/extreme gradient boosting, BERT demonstrated higher accuracy in both symptom domains, with 0.931 (95% CI 0.905-0.957) and 0.916 (95% CI 0.887-0.941) for problems with cognitive and social attributes on pain interference, respectively, and 0.929 (95% CI 0.903-0.953) and 0.917 (95% CI 0.891-0.943) for problems with cognitive and social attributes on fatigue, respectively. In addition, BERT yielded superior areas under the receiver operating characteristic curve for cognitive attributes on pain interference and fatigue domains (0.923, 95% CI 0.879-0.997; 0.948, 95% CI 0.922-0.979) and superior areas under the precision-recall curve for cognitive attributes on pain interference and fatigue domains (0.818, 95% CI 0.735-0.917; 0.855, 95% CI 0.791-0.930).

Conclusions
The BERT method performed better than the other methods. As an alternative to using standard PRO surveys, collecting unstructured PROs via interviews or conversations during clinical encounters and applying NLP/ML methods can facilitate PRO assessment in child and adolescent cancer survivors.
Benefits, Problems, and Potential Improvements in a Nationwide Patient Portal: Cross-sectional Survey of Pharmacy Customers’ Experiences
Authors: Sääskilahti Maria , Ojanen Anna , Ahonen Riitta , Timonen Johanna 
Published: November 2021

Background
Patient engagement is a worldwide trend in health care. Patient portals have the potential to increase patients’ knowledge about their health and care and therefore enhance patient engagement. Portal users’ experiences are needed to determine if these portals work appropriately and if there are barriers to achieving the aims that were set before their implementation.

Objective
The aim of this study is to analyze pharmacy customers’ experiences of the Finnish nationwide patient portal My Kanta in terms of benefits, problems, and potential improvements.

Methods
A questionnaire survey was conducted among pharmacy customers in the spring of 2019. The questionnaires (N=2866) were distributed from 18 community pharmacies across mainland Finland to customers aged ≥18 years who were purchasing prescription medicines for themselves or their children aged <18 years. Using open-ended questions, customers were asked about their experiences of the benefits and problems of My Kanta and what improvements could be made. Their responses were encoded and categorized using inductive content analysis, stored in SPSS Statistics for Windows, and analyzed using frequencies.

Results
Of the 2866 questionnaires, a total of 994 (34.68%) questionnaires were included in the analysis. Most respondents were My Kanta users (820/994, 82.5%); of these 820 users, 667 (81.3%) reported at least one benefit, 311 (37.9%) reported at least one problem, and 327 (39.9%) reported at least one potential improvement when using My Kanta. The most commonly mentioned benefits were opportunities to view health data (290/667, 43.5%) and prescriptions (247/667, 37%) and to renew prescriptions (220/667, 33%). The most extensively reported problems with My Kanta were that the portal lacks health data (71/311, 22.8%), navigating the service and searching for information is difficult (68/311, 21.9%), and the delay before health data are incorporated into the service (41/311, 13.2%). The most frequently suggested potential improvements were that My Kanta needs more comprehensive health data (89/327, 27.2%); the service should be easier to navigate and information easier to access (71/327, 21.7%); the service should have more functions (51/327, 15.6%); and health data should be entered into the portal more promptly (47/327, 14.4%).

Conclusions
Pharmacy customers reported more benefits than problems or potential improvements regarding the use of My Kanta. The service is useful for viewing health data and prescriptions and for renewing prescriptions. However, portal users would like to see more data and functions available in the portal and data searches to be made easier. These improvements could make the data and functions provided by the portal easier to view and use and hence promote patient engagement.
KAJIAN EFIKASI HERBISIDA AMETRIN DAN KOMBINASI AMETRIN + (2,4-D ATAU METIL METSULFURON) TERHADAP PERTUMBUHAN GULMA PADA BUDIDAYA TANAMAN TEBU LAHAN KERING
Authors: Susanto Herry , Evizal Rusdi , Sugiatno Sugiatno 
Published: November 2021

Weed control in dry land cane cultivation is usually done chemically with the pre-emergence herbicides spraying since planting until to one week and post-emergence for about 2.5 months. Pre-emergence herbicides are usually used to control weeds when planting until to 2 month periode and 2.5 months post-emergence herbicides to prepare a second fertilization so that sugar cane growth is not disturbed by weeds. The treatment consisted of: ametrine 80 % herbicide at doses of 0.8, 1.2, 1.6, 2.0; and 2.4 kg / ha, ametrine 1.6 kg/ha+2,4-D 865g l/ha,ametrine 1.6 kg/ha + metil metsulfuron 8 g/ha, 2 times manual weeding treatment, and control. The experimental design used was randomized block design with 4 replications. The results showed that the herbicides ametrine and ametrine + 2,4-D or metsulfuron methyl were able to suppress the total weeds growth in the cultivation of dry land sugarcane. Ametrine and ametrine + 2,4-D or metsulfuron methyl all doses are able to suppress weeds Borreria alata, Rhicardia brasiliensis, and Digitaria longifolia; except at doses of ametrine 0.8 and 1.2 kg/ha against Borreria alata at 8 and 12 weeks after application. Whereas weeds that are not controlled with all treatments, namely Brachiaria sp., Cyperus rotundus, and Cleome rutidosperma. The growth of plant cane is not suppressed by the treatment of herbicide ametrine and ametrine + 2,4-D or metsulfuron methyl and as well as manual weeding. The treatment of herbicide ametrine and ametrine + 2,4-D or metsulfuron methyl does not cause toxic in plant cane cultivation. Keywords: Ametrine, 2,4-D, metsulfuron methy, plant cane, weeds.