bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effects of an In-vehicle Collision Warning System on Older Drivers' On-road Head Movements at Intersections
Authors: Shichrur Rachel , Ratzon Navah Z. , Shoham Arava , Borowsky Avinoam 
Published: February 2021

With age might come a decline in crucial driving skills. The effect of a collision warning system (CWS) on older drivers' head movements behavior at intersections was examined.Methods: Twenty-six old-adults, between 55 and 64 years of age, and 16 Older drivers between 65 and 83 years of age, participated in the study. A CWS (Mobileye Inc.) and a front-back in-vehicle camera (IVC) were installed in each of the participants' own vehicles for 6 months. The CWS was utilized to identify unsafe events during naturalistic driving situations, and the IVC was used to capture head direction at intersections. The experimental design was conducted in three phases (baseline, intervention, and carryover), 2 months each. Unsafe events were recorded by the CWS during all phases of the study. In the second phase, the CWS feedback was activated to examine its effect on drivers' head movement' behavior at intersections.Results: Older drivers (65+) drove significantly more hours in total during the intervention phase (M = 79.1 h, SE = 10) than the baseline phase (M = 39.1 h, SE = 5.3) and the carryover phase (M = 37.7 h, SE = 5.4). The study revealed no significant differences between the head movements of older and old-adult drivers at intersections. For intersection on the left direction, a significant improvement in drivers' head movements' behavior was found at T-junctions, turns and four-way intersections from phase 1 to phase 3 (p &lt; 0.01), however, two intersection types presented a decrease along the study phases. The head movements' behavior at roundabouts and merges was better at phase 1 compared to phase 3 (p &lt; 0.01). There was no significant reduction of the mean number of CWS unsafe events across the study phases.Conclusions: The immediate feedback provided by the CWS was effective in terms of participants' head movements at certain intersections but was harmful in others. However, older drivers drove many more hours during the active feedback phase, implying that they trusted the system. Therefore, in the light of this complex picture, using the technological feedback with older drivers should be followed with an additional mediation or follow-up to ensure safety.
Efforts on Changing Lifestyle Behaviors May Not Be Enough to Improve Health-Related Quality of Life Among Adolescents: A Cluster-Randomized Controlled Trial
Authors: Bandeira Alexsandra da Silva , Beets Michael W. , Silveira Pablo Magno da , Lopes Marcus Vinicius Veber , Barbosa Filho Valter Cordeiro , da Costa Bruno G. G. , Silva Kelly Samara 
Published: February 2021

Schools have been the main context for physical activity (PA) and sedentary behavior (SB) interventions among adolescents, but there is inconsistent evidence on whether they also improve dimensions of the health−related quality of life (HRQoL). The aim of this study was to evaluate the effects of a school-based active lifestyle intervention on dimensions of HRQoL. A secondary aim was to verify whether sex, age, and HRQoL at baseline were moderators of the intervention effect. A cluster-randomized controlled trial was conducted at three control and three intervention schools in Florianopolis, Brazil. All students from 7th to 9th grade were invited to participate. A school year intervention, designed primarily to increase PA and reduce SB, included strategies focused on (i) teacher training on PA, SB, and nutrition, and availability of teaching materials related to these contents; (ii) environmental improvements (i.e., creation and revitalization of spaces for the practice of PA in school); and (iii) education strategies, with the availability of folders and posters regarding PA, SB, and nutrition. Participants and the research staffs were not blinded to group assignment, but a standardized evaluation protocol was applied at baseline and after the intervention (March and November 2017) using the KIDSCREEN−27 to assess HRQoL across five dimensions. Mixed linear models were performed to evaluate the effect of the Movimente intervention on the five HRQoL dimensions. Of the 921 students who answered the questionnaire at baseline, 300 and 434 completed the study in control and intervention groups, respectively (dropouts: 20%). The results revealed no significant effects of the intervention on any HRQoL dimensions. A reduction of the school environment dimension was observed in both the control (-2.44; 95% CI: -3.41 to -1.48) and intervention groups (-2.09; 95% CI: -2.89 to -1.30). Sensitivity analyses showed that students in the highest baseline tertiles of HRQoL in any dimension had a reduction in their respective scores from pre- to post-intervention in both school groups. In conclusion, our results demonstrated no intervention effect on HRQoL dimensions and those students with the highest levels of HRQoL at baseline on all dimensions reduced from pre to post-intervention.Clinical Trial RegistrationThe trial is registered at the Clinical Trial Registry (Trial ID: NCT02944318; date of registration: October 18, 2016).
Impairment in Emotional Intelligence May Be Mood-Dependent in Bipolar I and Bipolar II Disorders
Authors: Kuo Shih-Yu , Chang Yun-Hsuan , Wang Tzu-Yun , Tseng Huai-Hsuan , Huang Chih-Chun , Chen Po See , Lane Hsien-Yuan , Yang Yen Kuang , Lu Ru-Band 
Published: February 2021

Background: An emotional intelligence (EI) deficit has been noticed in euthymic bipolar spectrum disorder (BD) patients. However, whether this deficit is affected by mood or subtype is unclear.Objectives:The aim of this study was to investigate whether an EI deficit is mood-dependent, and which mood symptoms have more impact on EI in BD.Methods: Two hundred and thirty participants aged between 18 and 65 years old were recruited [130 BD patients (51 bipolar I disorder (BDI) and 79 bipolar II disorder (BDII): 39.2% males; 91 healthy controls (HCs): 48.4% males)]. The Mayer–Salovey–Caruso Emotional Intelligence Test (MSCEIT), which contains experiential and strategic EI ratings, was used to assess social cognition. The Hamilton Depression Rating Scale (HDRS) and the Young's Mania Rating Scale (YMRS) were used for evaluating the severity [HAMD and YMRS scores ≦7 were euthymic (BDeut) and HAMD YMRS sores ≧8 were episodic (BDepi)]. Analyses of covariance (ANCOVA) were performed, with adjustment for background information between the BD patients and HCs.Results: The results showed that, compared to the HCs, the BDeut patients showed no difference in any MSCEIT measures, while the BDepi patients showed lower scores in all MSCEIT measures, except for perceiving emotions. In addition, a main effect of mood state instead of BD subtype was found for the managing emotions branch (p &lt; 0.0007). Regression analyses showed that the duration of illness and HDRS scores were correlated with the scores in the strategic area of the MSCEIT, while age and YMRS scores were more relevant to the scores in the experiential area of the MSCEIT.Conclusion: The results confirm that an EI deficit is mood-dependent in BD patients. In addition, a depressive mood is more related to the strategic EI area, while a manic mood is correlated with the experiential EI area. Understanding the different domains of EI deficits in BD patients may be helpful for developing interventions for BD.
Intermittent Theta-Burst Stimulation Over the DorsoLateral PreFrontal Cortex (DLPFC) in Healthy Subjects Produces No Cumulative Effect on Cortical Excitability
Authors: Bouaziz Noomane , Laidi Charles , Thomas Fanny , Schenin-King Andrianisaina Palmyre , Moulier Virginie , Januel Dominique 
Published: February 2021

Background: Intermittent Theta Burst Stimulation (iTBS) is a design of repetitive Transcranial Magnetic Stimulation (rTMS) and could be a candidate to replace rTMS in the treatment of depression, thanks to its efficacy, shorter duration, and ease of use. The antidepressant mechanism of iTBS, and whether this mechanism is mediated by a modulation of cortical excitability, remains unknown.Methods: Using a randomized double-blind, sham-controlled trial, 30 healthy volunteers received either iTBS or a sham treatment targeting the left DorsoLateral PreFrontal Cortex (L-DLPFC), twice a day over 5 consecutive days. Cortical excitability was measured before and after the 5 days of stimulation.Results: No difference in cortical excitability was observed between active or sham iTBS.Conclusion: Our study does not support any effect on cortical excitability of repetitive iTBS targeting the L-DLPFC.
Misinformation Drives Low Human Papillomavirus Vaccination Coverage in South African Girls Attending Private Schools
Authors: Milondzo Tracy , Meyer Johanna C. , Dochez Carine , Burnett Rosemary J. 
Published: February 2021

Background: Cervical cancer, caused by persistent human papillomavirus (HPV) infection, is the leading cause of female cancer deaths in South Africa. In 2014, the South African National Department of Health introduced a free public sector school-based HPV vaccination programme, targeting grade 4 girls aged ≥9 years. However, private sector school girls receive HPV vaccination through their healthcare providers at cost. This study investigated HPV vaccination knowledge, attitudes and practices of caregivers of girls aged ≥9 years in grades 4–7 attending South African private schools.Methods: A link to an online survey was circulated to caregivers via an email sent to school principals of all private schools in four provinces enrolling girls in grades 4–7. Following a poor post-reminder response, a paid Facebook survey-linked advert targeting South African Facebook users aged ≥25 years nationally was run for 4 days, and placed on the South African Vaccination and Immunisation Centre's Facebook page for 20 days.Results: Of 615 respondents, 413 provided HPV vaccination data and 455 completed the knowledge and attitudes tests. Most (76.5%) caregivers had good knowledge and 45.3% had positive attitudes. Of their daughters, 19.4% had received ≥1 dose of HPV vaccine. Of caregivers of unvaccinated girls, 44.3% and 41.1%, respectively were willing to vaccinate their daughters if vaccination was offered free and at their school. Caregivers of unvaccinated girls were more likely [odds ratio (OR): 3.8] to have been influenced by “other” influences (mainly online articles and anecdotal vaccine injury reports). Of caregivers influenced by their healthcare providers, caregivers of unvaccinated girls were more likely (OR: 0.2) to be influenced by alternative medical practitioners. Caregivers of vaccinated girls were more likely to have good knowledge (OR: 3.6) and positive attitudes (OR: 5.2). Having good knowledge strongly predicted (OR: 2.8) positive attitudes. Having negative attitudes strongly predicted (OR: 0.2) girls being unvaccinated.Conclusion: Providing free school-based HPV vaccination in the private sector may not increase HPV vaccination coverage to an optimal level. Since misinformation was the main driver of negative attitudes resulting in &lt;20% of girls being vaccinated, an advocacy campaign targeting all stakeholders is urgently needed.
Cytotoxicity of Cultured Canine Primary Hepatocytes Exposed to Itraconazole Is Decreased by Pre-treatment With Glutathione
Authors: Kirk Natalie M. , Vieson Miranda D. , Selting Kim A. , Reinhart Jennifer M. 
Published: February 2021

Objective: To identify the effect of glutathione (GSH) on cell survival in a novel in vitro model of itraconazole (ITZ)-associated hepatotoxicity using canine primary hepatocytes.Sample: Commercially sourced, cryopreserved male dog (Beagle) primary hepatocytes from a single donor.Procedures: Using a sandwich culture technique, canine primary hepatocytes were exposed to serial dilutions of ITZ. Calcein AM, 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT), and neutral red were investigated as potential cell viability assays. Hepatocytes were then pre-incubated with GSH, exposed to serial dilutions of ITZ, and cell viability determined at 4 and 24 h post-ITZ exposure. Each condition was performed in technical triplicate and the effect of time, GSH concentration, and ITZ concentration on % cytotoxicity assessed using a multivariate linear regression model. Tukey's post-hoc test was used to detect individual differences.Results: The neutral red cell cytotoxicity assay was chosen based on its superior ability to detect dose-dependent changes in viability. Hepatocyte cytotoxicity significantly increased with ITZ concentration (P &lt; 0.001) and time (P = 0.004) and significantly decreased with GSH treatment (P &lt; 0.001).Conclusions and Clinical Relevance: This in vitro model demonstrates dose- and time-dependent ITZ-induced cytotoxicity, which is similar to clinical changes observed in canine patients and in in vivo rodent studies. Pre-treating with GSH is protective against in vitro cell death. These results suggest that GSH precursors may have a role in the management or prevention of ITZ-associated hepatotoxicity in dogs. Clinical trials are needed to evaluate their utility for this adverse drug reaction.
THE INFLUENCE OF E-DI STRUST, E-NEGATI VE BELIEFS, E-SELF INEFFICACY, E-LOGISTIC EASE, E-CONVENIENCE, E-ENJOYMENT AND SATISFACTION TOWARD LOYALTY BERRYBENKA CUSTOMERS
Authors: INDRIYANTI IRMA SATYA , APRILIA HANNY 
Published: February 2021

The aim of this research is to discover the influence of E-distrust, E-negative beliefs, E-self inefficacy, E-logistic ease, E-convenience, E-enjoyment on Satisfaction, and to discover the influence of Satisfaction on Loyalty. The design of this research is made with descriptive research and causal research. This research is aquantitative study by taking population from consumers who have accounts and shopping experience at Berrybenka website. The samples are taken from the population using purposive sampling method through questionnaires. Total of samples used in this study are 208 respondents. This study uses structural equation model (SEM) with the help of SmartPLS 3.0 analysis program. The results of this research are E-distrust, Enegative beliefs, E-self inefficacy, E-logistic ease, E-enjoyment has impact towards Satisfaction, E-convenience has no impact to Satisfaction, and Satisfaction has impact towards Loyalty.
Pelatihan Maintance Komputer SMAN Pagar Gunung
Authors: Mukti Yogi 
Published: February 2021

SMAN Pagar Gunung (Pagun) merupakan sekolah menengah daerah yang layak untuk menjadi tempat pengabdian civitas akademika Sekolah Tinggi Teknologi Pagaralam (STTP), hampir semua siswa SMAN Pagun tidak terlalu baik memahami hardware computer, pelatihan ini menjadi bukti semangat berbagi dari civitas STTP, tujuannya akhirnya adalah agar siswa memiliki softskills bidang pemahaman hardware computer. Metode yang digunakan untuk kelancaran kegiatan ini adalah menggunakan pre dan pos tes sehingga dapat langsung diperoleh kesimpulan tingkat pemahaman siswa terhadap materi pelatihan maintenance ini, hasilnya terlihat sangat memuaskan yang mana pada saat dilakukan pre tes tingkat pemahaman siswa terhadap hardware dan maintenance computer tidak terlalu baik dari 10 pertanyaan yang diberikan sama sekali tidak ada siswa yang mampu menjawab 100% benar, bahkan yang memiliki nilai 9 jawaban benar hanya 2%, yang menjawab 8 benar hanya 3% dari 20 peserta yang mengikuti pelatihan. Tetapi hasil pos tes sangat menggembirakan dimana terdapat hampir 5% siswa yang mencapai nilai 10 dan nilai 9 hampir 20% dari total peserta, sehingga disimpulkan pelatihan sangat penting dan mampu meningkatkan pemahaman yang signifikan.
Mechanical Properties of Cementitious and Non-Cementitious System After Ageing Tests for Well Abandonment Cementing Operations
Authors: da Silva Ingrid Ezechiello , Balthar Vivian Karla Castelo Branco Louback Machado , Toledo Filho Romildo Dias , de Sá Cavalcante Gabriella de Medeiros , dos Santos Robert Lucian de Lima 
Published: February 2021

The plug and Abandonment (P&A) are the final stage of the life cycle of an oil well. This implies that the plugging material must withstand the chemicals, temperature and well pressure to ensure its long-term integrity. Portland cement is the most used material as a safety barrier in P&A operations. However, the extreme conditions of the well have challenged the mechanical properties of Portland Cement. In this context, the present work aims to identify the adequate systems as permanent plugging material and to characterize them with a qualification process based on international references and experimental validation.
Hence, four systems were tested for plug cementing operation with composition variations under pre-defined ageing conditions. Class G Portland cement slurry was used as reference to allow comparison of mechanical properties (compressive strength and tensile strength) between flexible cement paste, a system containing a mixture of Class G Portland Cement with epoxy resin and finally a system with epoxy resin only. Samples containing Class G Portland Cement were cured for 14 days under well bottom conditions (3000 psi and temperature of 174 degrees Fahrenheit) and cured for 14 days at well temperature (using a thermal bath). Samples containing resin were cured for 14 days under well bottom conditions (3000 psi and temperature of 150 degrees Fahrenheit) and cured for 14 days at well temperature (using a thermal bath).
Finally, the samples were aged for 60 days in a thermal bath at well temperature and exposed to the brine which is the completion fluid composition which will be above and below in contact with the well barrier in a P & A operation. The results of the compressive strength tests of the samples aged in brine showed tha in some systems tested the reduction of the modulus of elasticity occurred, however, it was also observed the increase of the modulus of elasticity in another system. The same was true of the results of tensile strength tests of aged samples, the increase of rupture loading in some systems and reduction in the other ones were observed.
The mechanical tests of the samples before and after ageing were performed to define the best system to be used in a well abandonment operation aiming for long-term integrity.
Can spiral-shaped abdominal wall lift replace pneumoperitoneum in laparoscopic cholecystectomy? A randomised study
Authors: Shashi  , Singh Rajdeep , Mishra Anurag , Bains Lovenish , Agarwal P. N. 
Published: February 2021

Background:
A new design of abdominal lift system for gasless laparoscopy has been introduced in rural areas.

Aims and Objectives:
To assess whether the new spiral design abdominal wall lift system has similar outcomes to standard pneumoperitoneum laparoscopic cholecystectomy.

Materials and Methods:
Sixty cases of symptomatic gallstone disease scheduled for laparoscopic cholecystectomy were randomly assigned to gasless spiral abdominal wall lift or to standard pressure pneumoperitoneum, followed by cholecystectomy. Post-operative abdominal and shoulder tip pain, duration and ease of surgery and surgical site complications were compared.

Results:
There was a significant difference in post-operative abdominal pain at 24 hours after surgery (P < 0.01). Shoulder tip pain was lower at 6 h (P < 0.01). The duration of surgery was comparable in both groups; the time taken decreased in the abdominal lift procedure with increasing experience. Conversion rate and surgical site complications were similar. There were comparable outcomes in terms of overall post-operative abdominal pain; shoulder tip pain; duration of surgery; conversions and post-operative complications between the two groups. Ease of surgery improved with number of cases over time.

Conclusion:
Abdominal lift may be a valid alternative to pneumoperitoneum cholecystectomy with comparable outcomes in resource constrained areas.
Unite to end Tuberculosis – The need for public–private collaboration
Authors: Koshy Jency , Samuel Johnson Abel K. , Babu Bichu P. , Joseph Marina Rajan 
Published: February 2021

Background:
Despite effective diagnostic tools and drugs for tuberculosis, the disease still remains a public health threat. Financial insecurity, Social stigma, food insecurity, distance to nearest health facility and psychological stress play as hurdles in the diagnosis and completion of tuberculosis treatment. Early diagnosis and completion of treatment plays a key role in controlling tuberculosis. The public and the private sector in India together is trying hard to control this menace. The public sector in India has a wide network of institutions with uniform standardized treatment for TB treatment under the National tuberculosis program. The private sector is heterogeneous with limited or no extension centers in the peripheries. This makes it difficult for the private sector to follow up the patient. So the national program has extended the arms to join with the private partners to eliminate TB. This article attempts to highlight the need of collaborating with the national program to eliminate tuberculosis.

Materials and Methods:
All the tuberculosis patients diagnosed at a private institution prior to partnership with the national program were followed up to understand the treatment outcomes and understand the importance of public private collaboration.

Results:
A total of 131 patients were diagnosed with tuberculosis from the health facility during the study period. Out of the 131 patients, 30% (n = 39) could not be traced. Among the patients who were contacted, treatment interruption was observed in 6 (7%) patients. More than 1/4th of the traced patients (n = 62) completed their treatment. Death occurred to 08 (9%) traced patients.

Conclusion:
This study reiterate the need for Private public coordination in the treatment of TB. It is the responsibility of the health care professionals in the private sector to collaborate with the national tuberculosis program to make tuberculosis elimination a reality.