bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraoperative fluid management and kidney transplantation outcomes: A retrospective cohort study
Authors: Harbell Monica W. , Kraus Molly B. , Bucker‐Petty Skye A. , Harbell Jack W. 
Published: September 2021

AbstractBackgroundPatients undergoing kidney transplantation traditionally receive liberal amounts of fluid during surgery. However, excessive fluids can lead to fluid overload and ileus. In this retrospective cohort study, we compared the effect of restrictive versus liberal fluid therapy on kidney transplantation outcomes.MethodsPatients who underwent deceased‐donor kidney transplantation at Mayo Clinic from January 2014 to March 2019 were included. Those who received <3 L of intravenous fluids intraoperatively were categorized as “restrictive;” those who received ≥3 L were categorized as “liberal.” The primary outcome was incidence of delayed graft function (DGF). Secondary outcomes included length of stay, readmission within 30 days, time to return of bowel function, and incidence of postoperative complications.ResultsOf the 1171 patients included, 557 were in the restrictive group and 614 in the liberal group. The mean (SD) fluid intake was 2.17 (.54) L in the restrictive group and 3.67 (.68) L in the liberal group (P<.001). There was no difference in DGF (relative risk, 1.03; P = .56), length of stay (P = .34), readmission (P = .80), return of bowel function (P = .71), or other postoperative complications.ConclusionsIntraoperative restrictive fluid therapy during kidney transplantation was not associated with DGF or worse outcomes when compared with liberal fluid therapy.
The distribution of national urban hierarchies of connectivity within global city networks
Authors: Loginova Julia , Sigler Thomas , Searle Glen , O'Connor Kevin 
Published: September 2021

AbstractThis paper demonstrates how the national urban hierarchies can be understood through the lens of connectivity within globally scaled economic networks. We first examine the global city network structure using ak‐core decomposition method. Values ofk‐coreness are then used to understand the distribution of global connectivity within national urban systems. This is observed through a measure of statistical dispersion applied to a novel global dataset of 68,602 weighted headquarter‐subsidiary relations of 31,371 firms linking 4181 cities collected in 2019. Our results confirm the existence of a hierarchical core–periphery structure at a global scale, yet reveal varying degrees of hierarchy at a national scale. At a national scale, single‐core, double‐core or multi‐core network structures characterize the way in which national and global city networks intersect, indicating that there is a distinction between global cities as the core and urban‐systems‐as‐networks that connect nations to the global economy.
Critical Criminology and Race: Re‐examining the Whiteness of US Criminological Thought
Authors: LEÓN KENNETH SEBASTIÁN 
Published: September 2021

AbstractRace and racism are defining features of criminal justice systems in the United States. Race is also a defining feature of criminological theory. There have been robust efforts to address racism within theories and institutional practices pertaining to crime, law, and institutions of formal social control, but whiteness remains at the core of criminological knowledge production. The current article provides empirical support for showing how whiteness conditions the academic discourses of criminology and criminal justice (CCJ) in the United States. CCJ research plays an important role in discussions of racial justice and public policy. By studying the racialised (that is, white) nature of the CCJ research industry, we can better understand where critical criminology ‘fits’ in the broader struggle for social, racial and epistemological justice.
Halitosis, what experiences and methods apply Dutch dental hygienists
Authors: Elsenberg Catharina P.M. , Sidiqi Sana , Buunk‐Werkhoven Yvonne A.B. 
Published: September 2021

AbstractObjectivesThe aim of this research is to gain more insight in the methods and experiences of dental hygienists in the Netherlands regarding the treatment of patients with halitosis.Material and methodsA total of 92 dental hygienists completed the questionnaire (consisting of 19 questions on personal and professional characteristics, clinical observation and treatment of halitosis, the referral of patients with halitosis, the presence and usefulness of a protocol). The questionnaire was distributed using a social media platform for dental professionals in oral health care from all over the Netherlands.Results83.4% of 90 dental hygienists had paid attention to the patient's breath but only 37.8% of dental hygienists always informed the patient. Reasons for not informing patients were the fear of the patient's possible reaction or because other oral health problems were more important. Of the included dental hygienists 67.8% had never referred a patient for treatment of halitosis. 86.7% of the dental hygienists stated there was no protocol for diagnosis and treatment of patients with halitosis. However, 90.0% of the dental hygienists acknowledged a protocol would be useful.ConclusionsThe majority of the dental hygienists in the Netherlands had paid attention to the patient's breath, but only a small group of dental hygienists informed their patients about halitosis. In dental practices halitosis is an underestimated problem. During the coronavirus pandemic people are more aware with the smell of their breath. Dental hygienists indicated scaling and root planning and/or providing information and instruction by patients with a bad breath.
Comparing the use of silicone and polyurethane Peripherally Inserted Central Catheters in newborns: A retrospective study
Authors: Gomes de Souza Nayana Maria , Silveira Rocha Rebeca , Pinheiro Ferreira Roberta , Bastos da Silveira Reis Claudia , Souza Bandeira Roberta Sthephanie , Façanha Melo Ana Paula 
Published: September 2021

AbstractAims and objectivesTo compare polyurethane and silicone peripherally inserted central catheters (PICCs) in newborns regarding the success rates of insertion and duration and the reasons for nonelective removal.BackgroundPrevious studies have attempted to identify predictors of PICC complications in newborns, such as lower extremity insertion or femoral catheter insertion, procedures that require 60 minutes or more, duration longer than 30 days and non‐central position of the catheter tip. However, there is little evidence on which type of PICC material causes less complications, especially in newborns.DesignRetrospective cohort, guided by the STROBE tool.MethodsWe divided the newborns into two groups according to the type of PICC material: polyurethane and silicone. Our sample was composed of 449 PICCs, of which 246 polyurethane PICCs and 203 silicone PICCs, inserted in 294 newborns. Bivariate analysis was performed for data comparison. All statistically significant variables in the bivariate analysis were included in the logistic regression (p ≤ .05).ResultsOf the 449 PICCs that we analysed, the central position of the catheter tip predominated for both types of materials, with a higher prevalence of false passage for the polyurethane group. There was no difference between the average duration. The incidence of nonelective PICC removal was 49.27% for the silicone group, and infiltration/extravasation and rupture were among the reasons for nonelective removal.ConclusionThe overall success rates in the insertion and duration of the PICC were almost identical for both types of material, despite the high incidence of false passage for polyurethane PICCs. Nonelective removals were higher for silicone PICCs, which also had a higher incidence for infiltration/extravasation and rupture.Relevance to clinical practiceCan contribute to the knowledge of the strengths and weaknesses of polyurethane and silicone PICCs, with a view to reduce the incidence of nonelective removals.
Comparison of perinatal outcomes between controlled‐release dinoprostone vaginal delivery system (PROPESS) and metreurynter for cervical ripening in labor induction: A retrospective single‐center study in Japan
Authors: Yamaguchi Mizuki , Takakura Sho , Enomoto Naosuke , Teishikata Yasuhiro , Kitamura Asa , Maki Shintaro , Tanaka Kayo , Maezawa Tadashi , Tanaka Hiroaki , Ikeda Tomoaki 
Published: September 2021

AbstractAimThis study aimed to compare the efficacy and safety of a controlled‐release dinoprostone vaginal delivery system (PROPESS) and a metreurynter for labor induction.MethodsThis retrospective case‐controlled study included 117 pregnant women (51 and 66 in the PROPESS and metreurynter groups, respectively) who required labor induction after >37 weeks' gestation at Mie University Hospital between January 2018 and September 2020. The primary outcome was the success rate of vaginal delivery. The secondary outcomes were changes in the Bishop score from the first insertion of PROPESS or the metreurynter to removal, uterine hyperstimulation and non‐reassuring fetal status during the first insertion, proportion of pregnant women who needed pre‐delivery oxytocin after removal, time to vaginal delivery after the first insertion, proportion of pregnant women who delivered vaginally within 12 or 24 h after the first insertion, and neonatal outcomes.ResultsThe proportion of pregnant women, especially primiparas, who delivered vaginally was significantly higher in the PROPESS group (26/34 [76.5%]) than in the metreurynter group (25/52 [48.1%];p = 0.01). Moreover, among multiparas in the PROPESS group who delivered vaginally, nine (56.3%) out of 16 women delivered vaginally within 3 h of labor onset.ConclusionsPROPESS for cervical ripening may reduce the risk of undergoing cesarean section in pregnant women requiring labor induction, especially primiparas. It is important to consider the possibility of precipitate labor when using the PROPESS in multiparas.
LncRNA SCIRT absorbs miR‐221 to advance the expression of lncRNA GAS5 in oral squamous cell carcinoma to inhibit cancer cell apoptosis
Authors: Yang Lei , Yang Kaicheng , Wang Huichao , Chen Yanping , Zhao Jianguang 
Published: September 2021

AbstractBackgroundAlthough SCIRT has been reported to suppress breast cancer, its role in other cancers, such as oral squamous cell carcinoma (OSCC), is hardly known. We predicted that SCIRT might interact with miR‐221 to target lncRNA GAS5 and analyzed the interaction between SCIRT and miR‐221 in OSCC.MethodsSCIRT and miR‐221 expression levels were quantified using RT‐qPCR. SCIRT subcellular localization was analyzed by subcellular fractionation assay. RNA pull‐down assay was applied to study the interaction between SCIRT and miR‐221. The role of SCIRT and miR‐221 in regulating GAS5 expression was analyzed by overexpression assay and RT‐qPCR. Cell apoptosis was analyzed by flow cytometry.ResultsSCIRT and GAS5 were downregulated, while miR‐221 was overexpressed in OSCC. SCIRT was detected in both nucleus and cytoplasm and directly interacted with miR‐221, while SCIRT overexpression failed to affect miR‐221 expression. In addition, GAS5 expression was increased by SCIRT and decreased by miR‐221. Moreover, SCIRT suppressed the role of miR‐221 in suppressing GAS5 expression and OSCC cell apoptosis.ConclusionSCIRT sponges miR‐221 to upregulate lncRNA GAS5 in OSCC and inhibit cancer cell apoptosis.
The protein kinase SlCIPK23 boosts K+ and Na+ uptake in tomato plants
Authors: Amo Jesús , Lara Alberto , Martínez‐Martínez Almudena , Martínez Vicente , Rubio Francisco , Nieves‐Cordones Manuel 
Published: September 2021

AbstractRegulation of root transport systems is essential under fluctuating nutrient supply. In the case of potassium (K+), HAK/KUP/KT K+ transporters and voltage‐gated K+ channels ensure root K+ uptake in a wide range of K+ concentrations. In Arabidopsis, the CIPK23/CBL1‐9 complex regulates both transporter‐ and channel‐mediated root K+ uptake. However, research about K+ homeostasis in crops is in demand due to species‐specific mechanisms. In the present manuscript, we studied the contribution of the voltage‐gated K+ channel LKT1 and the protein kinase SlCIPK23 to K+ uptake in tomato plants by analysing gene‐edited knockout tomato mutant lines, together with two‐electrode voltage‐clamp experiments in Xenopus oocytes and protein–protein interaction analyses. It is shown that LKT1 is a crucial player in tomato K+ nutrition by contributing approximately 50% to root K+ uptake under K+‐sufficient conditions. Moreover, SlCIPK23 was responsible for approximately 100% of LKT1 and approximately 40% of the SlHAK5 K+ transporter activity in planta. Mg+2 and Na+ compensated for K+ deficit in tomato roots to a large extent, and the accumulation of Na+ was strongly dependent on SlCIPK23 function. The role of CIPK23 in Na+ accumulation in tomato roots was not conserved in Arabidopsis, which expands the current set of CIPK23‐like protein functions in plants.
Orthotopic heart transplant in a pediatric patient with mixed connective tissue disease
Authors: Miller Chelsea , White Shelby , L’Ecuyer Thomas , McCulloch Michael 
Published: September 2021

AbstractBackgroundPatients with autoimmune inflammatory syndromes such as mixed connective tissue disease (MCTD) and systemic lupus erythematosus have previously been considered marginal candidates for orthotopic heart transplant (OHT).MethodsA retrospective chart review was completed for this case report.ResultsWe present the case of an 11‐year‐old girl with known MCTD who developed congestive heart failure refractory to medical therapy and underwent OHT.ConclusionsDespite her autoimmune condition, this patient has not experienced antibody‐mediated rejection post‐transplant and her inflammatory symptoms have greatly improved.
Total platelet donation count and donation frequency are determinants of plateletpheresis‐associated lymphopenia
Authors: Thuer Linda , Brosig Andreas , Hutchinson James A. , Hähnel Viola , Offner Robert , Burkhardt Ralph , Ahrens Norbert 
Published: September 2021

AbstractBackgroundPlateletpheresis using a leukocyte reduction system (LRS) traps donor WBCs in the LRS chamber, which may lead to lymphopenia, especially in frequent plateletpheresis donors. It seems plausible that this might cause adverse effects. However, current knowledge about potential confounders and donor health impacts is incomplete.Donors and methodsRecent platelet donors and donations collected at University Hospital Regensburg from 2016 to 2019 using the Terumo BCT Trima Accel LRS system were retrospectively analyzed and compared with historical platelet donors and donations collected mainly with Fresenius Kabi Amicus non‐LRS system from 2010 to 2013. Additionally, recent donors were prospectively surveyed using a health‐related topics questionnaire.ResultsAnalysis of 819 recent donors with 11,254 blood counts and 1464 questionnaires and 1011 historical donors with 12,848 blood counts revealed that increased annual platelet donation frequencies were associated with decreased lymphocyte counts in both groups. Median lymphocyte counts in recent donors with no versus ≥24 previous annual donations declined from 2.0 to 1.2 × 103/μL (p < 2.2 × 10−16), and those in historical donors with no versus ≥24 previous annual donations decreased from 2.0 to 1.5 × 103/μL (p = 6 × 10−4), respectively. The questionnaire results showed that donation frequency and lymphopenia were not associated with upper respiratory tract infection (URTI) incidence or duration, but platelet donors who concomitantly donated granulocytes had significantly shorter URTI durations than those who did not (p = .008).ConclusionThis study confirmed that plateletpheresis‐associated lymphopenia occurs in LRS and to a lesser degree in non‐LRS platelet donors, but revealed no evidence of a negative impact on donor health.
Profile of the single‐use, multiple‐pass protein A adsorber column in immunoadsorption
Authors: Schossee Nadine , Veit Gabriele , Gittel Julia , Viebahn Johannes , Niklaus Marius , Klingler Philipp , Üçeyler Nurcan , Klinker Erdwine , Kobsar Anna , Boeck Markus , Koessler Juergen 
Published: September 2021

AbstractBackground and ObjectivesImmunoadsorptions (IA) are used to remove autoantibodies from the plasma in autoimmune disorders. In this study, we evaluated the effects of a single‐use, recombinant staphylococcal protein A‐based immunoadsorber on blood composition of the patient.Materials and MethodsIn a cohort of patients with myasthenia gravis or stiff‐person syndrome, essential parameters of blood cell count, coagulation, clinical chemistry or plasma proteins and immunoglobulins (Ig) were measured before and after IA (n = 11).ResultsIn average, IA reduced the levels of total IgG, IgG1, IgG2 and IgG4 by approximately 60%, the acetylcholine receptor autoantibody levels by more than 70%. IgG3, IgA or IgM were diminished to a lower extent. In contrast to fibrinogen or other coagulation factors, the column markedly removed vitamin K‐dependent coagulation factors II, VII, IX and X by approximately 40%–70%. Accordingly, international normalized ratio and activated partial thromboplastin time were increased after IA by 59.1% and 32.7%, respectively. Coagulation tests almost returned to baseline values within 24 h. Blood cell count, electrolytes, total protein or albumin were not essentially affected. No clinical events occurred.ConclusionThe single‐use, multiple‐pass protein A adsorber column is highly efficient to remove IgG1, IgG2 and IgG4 or specific acetylcholine receptor autoantibodies from the plasma. Coagulation parameters should be monitored, since the column has the capacity to largely reduce vitamin K‐dependent factors.
Production Characteristics, Evaluation, and Prediction of CO2 Water-Alternating-Gas Flooding in Tight Oil Reservoir
Authors: Chai Xiaolong , Tian Leng , Zhang Mengyuan , Shao Hongzhi , Wang Jianguo , Zhang Kaiqiang 
Published: September 2021

Abstract
It is complex and obviously different for the production characteristics of CO2 water-alternating-gas (WAG) flooding in tight reservoir and influenced by quite a few factors. Therefore, the prediction of oil production is a key matter of efficient development of CO2 WAG to be solved in tight reservoirs. In order to cope with this issue, in this paper, the production characteristics of CO2 WAG flooding are analyzed and classified in tight oil reservoir of block A as an example. On this basis, properties of reservoir, fracture factors, and operational factors are taken into account and the sensitivity of the influencing factors is carried out. Subsequently, the gray relation analysis is used to confirm the primary influencing factors. Finally, the evaluated model is established to predict oil production rapidly. The results illustrate that the wells of CO2 WAG flooding in tight reservoirs can be divided into four types of fluid production characteristics. The production is affected by permeability, reservoir thickness, amount of sand entering the ground, amount of liquid entering the ground, gas/water ratio, the injection rate, injection pressure, permeability variation coefficient, water sensitive index, acid sensitive index, and expulsion pressure. And the primary influencing factors are the amount of sand entering the ground, reservoir thickness, and amount of liquid entering the ground. The oil production can be predicted quickly based on the relation between production and comprehensive evaluation factor of production. The average relative error between the predicted results and the actual production is 8%, which proves the reliability and accuracy of this method.
Supports
Authors: Becht Charles 
Published: September 2021

Requirements for supports and other devices to restrain the piping are provided in Chapter II of ASME B31.3, specifically in Section 321, Piping Support.
ASME B31.3 provides general requirements for piping supports as well as descriptions of conditions for which they must be designed. The support elements (e.g., springs, hanger rods, etc.) are within the scope of ASME B31.3, but the support structures to which they are attached are not. The supports must achieve the objectives in the design of the piping for sustained and occasional loads as well as thermal displacement.
Paleogeographic position of the central Dodecanese Islands, southeastern Greece: The push-pull of Pelagonia
Authors: Grasemann B. , Schneider D.A. , Soukis K. , Roche V. , Hubmann B. 
Published: September 2021

Abstract
The paleogeographic position of the central Dodecanese Islands at the transition between the Aegean and Anatolian plates plays a considerable role in understanding the link between both geologically unique domains.
In this study, we investigate the tectonic history of the central Dodecanese Islands and the general correlation with the Aegean and western Anatolian and focus on the poorly studied islands of Kalymnos and Telendos. Three different major tectonic units were mapped on both islands from bottom to top: (1) The Kefala Unit consists of late Paleozoic, fossil-rich limestones, which have been deformed into a SE-vergent fold-and-thrust belt sealed by an up to 200-m-thick wildflysch-type olistostrome with marble and ultramafic blocks on a scale of tens of meters. (2) The Marina Basement Unit consists of a Variscan amphibolite facies basement with garnet mica schists, quartzites, and amphibolites. (3) Verrucano-type formation violet shales and Mesozoic unmetamorphosed limestones form the Marina Cover Unit. Correlation of these units with other units in the Aegean suggests that Kalymnos is paleogeographically located at the southern margin of the Pelagonian domain, and therefore it was in a structurally upper tectonic position during the Paleogene Alpine orogeny.
New white mica 40Ar/39Ar ages confirm the Carboniferous deformation of the Marina Basement Unit followed by a weak Triassic thermal event. Single-grain white mica 40Ar/39Ar ages from pressure solution cleavage of the newly defined Telendos Thrust suggest that the Marina Basement Unit was thrusted toward the north on top of the Kefala Unit in the Paleocene. Located at a tectonically upper position, the units exposed in the central Dodecanese escaped subduction and the syn-orogenic, high-pressure metamorphism. However, these units were affected by post-orogenic extension, and the contact between the Marina Basement Unit and the non-metamorphic Marina Cover Unit has been reactivated by the cataclastic top-to-SSW, low-angle Kalymnos Detachment. Zircon (U-Th)/He ages from the Kefala and Marina Basement Units are ca. 30 Ma, which indicates that exhumation and cooling below the Kalymnos Detachment started in the Oligocene. Conjugate brittle high-angle normal fault systems, which resulted in the formation of four major WNW-ESE–trending graben systems on Kalymnos, localized mainly in the Marina Cover Unit and probably rooted in the mechanically linked Kalymnos Detachment. Since Oligo-Miocene deformation in the northern Dodecanese records top-to-NNE extension and the Kalymnos Detachment accommodated top-to-SSW extension, we suggest that back-arc extension in the whole Aegean realm and transition to the Anatolian plate is bivergent.