bluuebunny/crossref_metadata_2025_split huggingface dataset:
Feminism and futurity: Geographies of resistance, resilience and reworking
Authors: MacLeavy Julie , Fannin Maria , Larner Wendy 
Published: April 2021

This article is designed to stimulate debate over the possibilities for thinking feminist futures. It argues for moving away from a linear understanding of feminism which assumes that past feminism produces present and future feminism as a response to its previous waves. Instead, we argue for embracing the multiplicity and simultaneity of contemporary feminisms, taking inspiration from Elizabeth Grosz’s writings on futurity and Cindi Katz’s work on resistance, resilience and reworking. Drawing on Katz’s framing, we review three analytically distinct ways of conceptualising feminist politics and consider how feminist geographers are asking new questions of familiar domains, as well as finding gender formations and political possibilities in unexpected empirical sites. In doing so, we point to the contemporary relevance of feminist scholarship and politics, and affirm feminism's ongoing importance.
Is Risk of Secondary Surgery for Oronasal Fistula Following Primary Cleft Palate Repair Associated With Hospital Case Volume and Cost-to-Charge Ratio?
Authors: Vu Giap H. , Kalmar Christopher L. , Zimmerman Carrie E. , Humphries Laura S. , Swanson Jordan W. , Bartlett Scott P. , Taylor Jesse A. 
Published: April 2021

Objective: This study assesses the association between risk of secondary surgery for oronasal fistula following primary cleft palate repair and 2 hospital characteristics—cost-to-charge ratio (RCC) and case volume of cleft palate repair. Design: Retrospective cohort study. Setting: This study utilized the Pediatric Health Information System (PHIS) database, which consists of clinical and resource-utilization data from >49 hospitals in the United States. Patients and Participants: Patients undergoing primary cleft palate repair from 2004 to 2009 were abstracted from the PHIS database and followed up for oronasal fistula repair between 2004 and 2015. Main Outcome Measure(s): The primary outcome measure was whether patients underwent oronasal fistula repair after primary cleft palate repair. Results: Among 5745 patients from 45 institutions whom met inclusion criteria, 166 (3%) underwent oronasal fistula repair within 6 to 11 years of primary cleft palate repair. Primary palatoplasty at high-RCC facilities was associated with a higher rate of subsequent oronasal fistula repair (odds ratio [OR] = 1.84 [1.32-2.56], adjusted odds ratio [AOR] = 1.81 [1.28-2.59]; P ≤ .001). Likelihood of surgery for oronasal fistula was independent of hospital case volume (OR = 0.83 [0.61-1.13], P = .233; AOR = 0.86 [0.62-1.20], P = .386). Patients with complete unilateral or bilateral cleft palate were more likely to receive oronasal fistula closure compared to those with unilateral-incomplete cleft palate (AOR = 2.09 [1.27-3.56], P = .005; AOR = 3.14 [1.80-5.58], P < .001). Conclusions: Subsequent need for oronasal fistula repair, while independent of hospital case volume for cleft palate repair, increased with increasing hospital RCC. Our study also corroborates complete cleft palate and cleft lip as risk factors for oronasal fistula.
The untold perspective: Parents’ experiences of the autism spectrum disorder assessment process when the child did not receive a diagnosis
Authors: Bendik Lesley-Anne , Spicer-White Freya 
Published: April 2021

This research explored parents’ lived experience of the autism spectrum disorder assessment process when a diagnosis was not received. Six mothers and one stepfather were interviewed and transcripts were analysed using interpretative phenomenological analysis. The identified themes: ‘My child is different’, The emotional and psychological journey and Understanding the outcome, illustrated issues encountered by parents during the assessment process and parenting a child with autistic-like characteristics but without a valid label. As a previously understudied area, clinical implications at the professional, service and policy level are discussed. Lay abstract Autism is diagnosed by a process of child assessment and parental interview. It has been well-documented by parents of children who received a diagnosis of autism, that the process can be lengthy and cause distress for families. Nevertheless, the outcome often compensated for the difficult assessment journey as it enables families to gain access to further information, support and intervention. However, less is known about the assessment process from parents who undertake the same process but at the end are told their child does not meet the diagnostic criteria, meaning no diagnosis is given. We interviewed six parents in North Wales, whose child did not receive a diagnostic of autism following an assessment. During the interview, parents were asked about their experience of the autism assessment process. We found that parents reflected on their experience according to three themes: (1) parents tried to navigate how they could make sense of their child being different despite not receiving a diagnosis; (2) parents referred to the assessment process as a journey, which encompassed many emotional and psychological components and (3) parents discussed what it was like to hear a non-diagnosis outcome, in terms of feeling relieved, confused and raising questions for the child’s future. These findings are important for professionals working in autism assessment services to help improve the assessment process for families, particularly when the assessment does not result in a diagnosis.
Étude sur la transférabilité d’une intervention d’éducation en santé dans le parc HLM : une méthode de recherche à l’épreuve du transfert pour décrire autrement les fonctions-clés
Authors: Trévidy Frédérique , Torrot-Arrocet Daniela , Brunie Vanida , Makdessi Peyronnie Marie , Wolfrom Jacques , Brugidou Guillaume , Gagnayre Rémi 
Published: April 2021

La transférabilité des interventions en santé est un enjeu essentiel à la réduction des inégalités sociales de santé. Mais ces interventions sont complexes et leur efficacité n’est pas garantie lors d’un transfert d’un contexte à l’autre. La description des fonctions-clés des interventions concourt à une meilleure transférabilité. Toutefois, celle-ci repose rarement sur une méthode permettant de concevoir l’intervention en situation de transfert. Cet article explicite le processus méthodologique permettant l’identification des fonctions-clés de l’intervention en situation de transfert, et leurs déclinaisons nommées : « éléments de passation » (EP). Nous nous sommes appuyés sur une recherche collaborative orientée par la conception (RoC) visant à concevoir une intervention d’éducation pour les locataires âgés du parc social, leur permettant de décider et d’agir pour adapter leur logement à leurs besoins. Deux cycles de recherche sont menés au sein d’entreprises sociales pour l’habitat (ESH) avec des comités de recherche réunissant chercheurs, locataires et professionnels. Plusieurs étapes collaboratives ont été nécessaires : l’étude du contexte de l’ESH1 et la création d’une culture commune ; la formation des professionnels impliqués dans l’intervention d’éducation ; la déclinaison du modèle selon les critères de transférabilité d’ASTAIRE (outil pour l’analyse de la transferabilité des interventions en promotion de la santé) ; l’identification des variations et des éléments stables du modèle au moment du transfert vers deux autres ESH ; l’identification des fonctions-clés du modèle et de ses « éléments de passation ». À l’épreuve du transfert, l’intervention est décrite en quatre catégories de fonctions-clés, déclinées en EP. Les EP sont des résultats issus de la RoC jugés signifiants par les acteurs de la recherche. Ce sont des phénomènes explicatifs révélant des situations à prévoir pour réussir le transfert et rendre l’intervention efficace. Ils permettent de donner sens aux fonctions-clés pour que les acteurs souhaitant transférer l’intervention dans leur contexte puissent mieux s’y préparer.
Faciliter et soutenir le retour au travail après un cancer du sein : partenariat chercheurs-acteurs dans un processus de modélisation d’une intervention
Authors: Fassier Jean-Baptiste , Rouat Sabrina , Guittard Laure , Broc Guillaume , Carretier Julien , Peron Julien , Sarnin Philippe , Fervers Béatrice , Letrilliart Laurent , Lancelot Léa , Baka Selma , Bouché Marion Lamort 
Published: April 2021

Introduction : La reprise du travail après un cancer favorise le rétablissement de la participation sociale mais se heurte à différents obstacles. Le projet FASTRACS vise à développer, implanter et évaluer une intervention pour faciliter le maintien en emploi après un cancer du sein. Le développement de l’intervention repose sur le protocole de l’Intervention Mapping. L’objectif de cet article est de décrire les contributions du partenariat chercheurs-acteurs dans le processus de modélisation de l’intervention durant les étapes du protocole de l’Intervention Mapping. Méthodes : Le processus de développement de l’intervention est reconstitué de façon chronologique en décrivant les méthodes mobilisées et les résultats obtenus à chaque étape du protocole grâce au partenariat chercheurs-acteurs. Résultats : Les membres du Comité stratégique (COS) ont été choisis par échantillonnage théorique parmi quatre catégories d’acteurs concernées. Une charte a été coécrite pour structurer durablement le partenariat. Les membres du COS ont contribué à l’échantillonnage des participants à l’enquête qualitative d’évaluation des besoins et à l’interprétation des résultats. Les objectifs de l’intervention ont été hiérarchisés selon leur importance et leur faisabilité perçues. Les chercheurs et membres du COS ont évalué les outils de l’intervention et débattu sur le modèle logique de l’intervention. Les professionnels de santé participant au COS ont facilité l’adhésion des équipes d’oncologie participant à l’intervention. Discussion : La construction du partenariat a permis de modifier les représentations des chercheurs. L’établissement de relations de confiance a nécessité du temps et de partager ses limites. Il a été difficile d’intégrer des patientes socialement défavorisées. Le recours accru à des patientes-expertes devrait être encouragé. Conclusion : La construction d’un partenariat de recherche collaborative entre chercheurs et acteurs nécessite du temps, des méthodes, et des financements dédiés. Cet investissement est de nature à améliorer la pertinence, l’acceptabilité, la légitimité et la pérennité des interventions développées.
Impact of implementing structured note templates on data capture for hernia surgery
Authors: Vetter Christopher David , Kim John H 
Published: April 2021

Background: Electronic medical record notes have been determined to be lacking in quality, accessibility and content. Structured note templates could provide a way to improve these aspects, particularly with regard to data availability for research and quality improvement. Objective: To determine whether the implementation of a standardised template for hernia documentation can improve data completeness and timeliness. Method: Retrospective review of clinic notes of 30 patients, 15 prior to implementation of a standardised note template and 15 after implementation of the template. The number of the 21 Americas Hernia Society Quality Collaborative (AHSQC) variables which were present in the notes was recorded, as was the time that the consultation ended and the time that the note was submitted. Results: Mean number of variables collected prior to implementation of the template was 5.9 ± 1.6 vs. 20 ± 0.4 after implementation ( p < 0.001). In the pre-implementation group, 20% of the notes were completed after the day of the visit, while all of the notes in the post-implementation group were completed on the same day as the visit ( p = 0.367). Conclusion: Implementation of a structured note template resulted in significantly improved capture of specific database variables within clinical notes. Structured note templates are an effective tool to improve data capture from the clinical setting for research and quality improvement.
New Onset Sacroiliac Joint Pain After Transforaminal Interbody Fusion: What Are the Culprits?
Authors: Kalidindi Kalyan Kumar Varma , Bansal Kuldeep , Vishwakarma Gayatri , Chhabra Harvinder Singh 
Published: April 2021

Study Design: A retrospective case-control study. Objective: Only a few studies have studied the incidence of new-onset SI joint pain following lumbar spine fusion surgery. We aimed to explore the association between new-onset SI joint pain following Transforaminal Lumbar Interbody Fusion (TLIF) for degenerative spine disorders and changes in spinopelvic parameters. Methods: A retrospective review of hospital records and imaging database of a tertiary care institute was done for patients who underwent TLIF from October 2018 to October 2019. The 354 patients who satisfied the eligibility criteria were divided into 2 groups(Group A, new-onset SI joint pain group, n = 34 and Group B, normal controls, n = 320). Symptomatic relief (>70% reduction in the VAS [Visual Analogue Scale] score) after 15 minutes of SI joint injection was considered diagnostic of SI joint pain. Clinical and radiological spinopelvic parameters were compared between the 2 groups. Results: Patients with postoperative SI joint pain (Group A) had significantly less preoperative and postoperative lumbar lordosis (p < 0.001) compared to the other group. Most of the patients in Group A had a cephalad migration of the apex postoperatively (30/34 patients) whereas majority of patients in group B had either predominant caudal migration (44/320 patients) or no migration of the lumbar apex (272/320 patients). Conclusions: The preoperative and postoperative lumbar lordosis are significantly less and the postoperative pelvic tilt is significantly high in patients with new-onset SI joint pain compared to the control group. The cephalad migration of the lumbar apex is significantly associated with new-onset SI joint pain.
Does the Intradiscal Injection of Platelet Rich Plasma Have Any Beneficial Role in the Management of Lumbar Disc Disease?
Authors: Muthu Sathish , Jeyaraman Madhan , Chellamuthu Girinivasan , Jeyaraman Naveen , Jain Rashmi , Khanna Manish 
Published: April 2021

Study Design: Systematic review and meta-analysis. Objectives: We performed this meta-analysis to evaluate whether intradiscal Platelet Rich Plasma(PRP) injection has any beneficial role in the management of lumbar disc disease. Methods: We conducted independent and duplicate electronic database searches including PubMed, Embase, and Cochrane Library till September 2020 for studies investigating the role of intradiscal PRP in the management of lumbar disc disease. The analysis was performed in the R platform using OpenMeta[Analyst] software. Results: 13 studies including 2 RCTs, 5 prospective, and 6 retrospective studies involving 319 patients were included in the meta-analysis. A single-arm meta-analysis of the included studies showed a beneficial effect of the intervention in terms of pain relief outcomes like VAS score (p < 0.001), pain component of SF-36 (p = 0.003) while such improvement was not seen in functional outcome measures like ODI score (p = 0.071), the physical component of SF-36 (p = 0.130) with significant heterogeneity noted among the included studies. No structural improvement in magnetic resonance imaging was observed (p = 0.106). No additional procedure-related adverse events were noted in the included studies (p = 0.662). Conclusion: There is a paucity of high-quality studies to give conclusive evidence on the benefits of intradiscal PRP for lumbar disc disease. Although intradiscal PRP injection has shown some beneficial effect in controlling pain for lumbar disc disease, we could not find structural or functional improvement from the included studies. Hence, we recommend large double-blind double-arm randomized controlled studies to analyze the benefits of the intervention being analyzed.
Urinary N-terminal pro–B-type natriuretic peptide as a biomarker for cardiovascular events in a general Japanese population: the Hisayama Study
Authors: Yamasaki Keisuke , Hata Jun , Ide Tomomi , Nagata Takuya , Sakata Satoko , Yoshida Daigo , Honda Takanori , Hirakawa Yoichiro , Nakano Toshiaki , Kitazono Takanari , Tsutsui Hiroyuki , Ninomiya Toshiharu 
Published: April 2021

Abstract
Background
Epidemiological evidence has shown that serum N-terminal pro-brain natriuretic peptide (NT-proBNP) concentrations, a diagnostic biomarker for heart failure, are positively associated with cardiovascular risk. Since NT-proBNP in serum is excreted in urine, it is hypothesized that urinary NT-proBNP concentrations are correlated with serum concentrations and linked with cardiovascular risk in the general population.

Methods
A total of 3060 community-dwelling residents aged ≥ 40 years without history of cardiovascular disease (CVD) were followed up for a median of 8.3 years (2007–2015). Serum and urinary concentrations of NT-proBNP at baseline were compared. The hazard ratios (HRs) and their 95% confidence intervals (CIs) for the association between NT-proBNP concentrations and the risk of developing CVD were computed using the Cox proportional hazards model.

Results
The median values (interquartile ranges) of serum and urinary NT-proBNP concentrations at baseline were 56 (32–104) pg/mL and 20 (18–25) pg/mL, respectively. There was a strong quadratic correlation between the serum and urinary concentrations of NT-proBNP (coefficient of determination [R2] = 0.72): urinary concentrations of 20, 27, and 43 pg/mL were equivalent to serum concentrations of 55, 125, and 300 pg/mL, respectively. During the follow-up period, 170 subjects developed CVD. The age- and sex-adjusted risk of CVD increased significantly with higher urinary NT-proBNP levels (P for trend < 0.001). This association remained significant after adjustment for traditional cardiovascular risk factors (P for trend = 0.009). The multivariable-adjusted risk of developing CVD almost doubled in subjects with urinary NT-proBNP of ≥ 43 pg/mL as compared to those with urinary NT-proBNP of ≤ 19 pg/mL (HR 2.07, 95% CI 1.20–3.56).

Conclusions
The present study demonstrated that urinary NT-proBNP concentrations were well-correlated with serum concentrations and were positively associated with cardiovascular risk. Given that urine sampling is noninvasive and does not require specially trained personnel, urinary NT-proBNP concentrations have the potential to be an easy and useful biomarker for detecting people at higher cardiovascular risk.
A risk assessment tool for resumption of research activities during the COVID-19 pandemic for field trials in low resource settings
Authors:   HAPIN Investigators, Simkovich Suzanne M. , Thompson Lisa M. , Clark Maggie L. , Balakrishnan Kalpana , Bussalleu Alejandra , Checkley William , Clasen Thomas , Davila-Roman Victor G. , Diaz-Artiga Anaite , Dusabimana Ephrem , Fuentes Lisa de las , Harvey Steven , Kirby Miles A. , Lovvorn Amy , McCollum Eric D. , Mollinedo Erick E. , Peel Jennifer L. , Quinn Ashlinn , Rosa Ghislaine , Underhill Lindsay J. , Williams Kendra N. , Young Bonnie N. , Rosenthal Joshua 
Published: April 2021

Abstract
Rationale
The spread of severe acute respiratory syndrome coronavirus-2 has suspended many non-COVID-19 related research activities. Where restarting research activities is permitted, investigators need to evaluate the risks and benefits of resuming data collection and adapt procedures to minimize risk.

Objectives
In the context of the multicountry Household Air Pollution Intervention (HAPIN) trial conducted in rural, low-resource settings, we developed a framework to assess the risk of each trial activity and to guide protective measures. Our goal is to maximize the integrity of reseach aims while minimizing infection risk based on the latest scientific understanding of the virus.

Methods
We drew on a combination of expert consultations, risk assessment frameworks, institutional guidance and literature to develop our framework. We then systematically graded clinical, behavioral, laboratory and field environmental health research activities in four countries for both adult and child subjects using this framework. National and local government recommendations provided the minimum safety guidelines for our work.

Results
Our framework assesses risk based on staff proximity to the participant, exposure time between staff and participants, and potential viral aerosolization while performing the activity. For each activity, one of four risk levels, from minimal to unacceptable, is assigned and guidance on protective measures is provided. Those activities that can potentially aerosolize the virus are deemed the highest risk.

Conclusions
By applying a systematic, procedure-specific approach to risk assessment for each trial activity, we were able to protect our participants and research team and to uphold our ability to deliver on the research commitments we have made to our staff, participants, local communities, and funders. This framework can be tailored to other research studies conducted in similar settings during the current pandemic, as well as potential future outbreaks with similar transmission dynamics.
The trial is registered with clinicaltrials.gov NCT02944682 on October 26. 2016 .
Comparative diagnostic accuracy studies with an imperfect reference standard – a comparison of correction methods
Authors: Umemneku Chikere Chinyereugo M. , Wilson Kevin J. , Allen A. Joy , Vale Luke 
Published: April 2021

Abstract
Background
Staquet et al. and Brenner both developed correction methods to estimate the sensitivity and specificity of a binary-response index test when the reference standard is imperfect and its sensitivity and specificity are known. However, to our knowledge, no study has compared the statistical properties of these methods, despite their long application in diagnostic accuracy studies.

Aim
To compare the correction methods developed by Staquet et al. and Brenner.

Methods
Simulations techniques were employed to compare the methods under assumptions that the new test and the reference standard are conditionally independent or dependent given the true disease status of an individual. Three clinical datasets were analysed to understand the impact of using each method to inform clinical decision-making.

Results
Under the assumption of conditional independence, the Staquet et al. correction method outperforms the Brenner correction method irrespective of the prevalence of disease and whether the performance of the reference standard is better or worse than the index test. However, when the prevalence of the disease is high (> 0.9) or low (< 0.1), the Staquet et al. correction method can produce illogical results (i.e. results outside [0,1]). Under the assumption of conditional dependence; both methods failed to estimate the sensitivity and specificity of the index test especially when the covariance terms between the index test and the reference standard is not close to zero.

Conclusion
When the new test and the imperfect reference standard are conditionally independent, and the sensitivity and specificity of the imperfect reference standard are known, the Staquet et al. correction method outperforms the Brenner method. However, where the prevalence of the target condition is very high or low or the two tests are conditionally dependent, other statistical methods such as latent class approaches should be considered.