bluuebunny/crossref_metadata_2025_split huggingface dataset:
Khảo sát tỷ lệ rối loạn chức năng tâm trương thất trái ở bệnh nhân đái tháo đường típ 2
Authors: Nguyễn Thu Hiền , Phạm Thanh Tùng 
Published: May 2021

Đặt vấn đề: Rối loạn chức năng tâm trương thất trái (LVDD) xuất hiện sớm ở những bệnh nhân đái tháo đường típ 2 không triệu chứng và thường bị chẩn đoán nhầm trong thực hành lâm sàng. Mục tiêu: Xác định tỷ lệ của rối loạn chức năng tâm trương thất trái ở bệnh nhân đái tháo đường típ 2 và các đặc điểm lâm sàng và xét nghiệm liên quan. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả, cắt ngang trên 118 bệnh nhân đái tháo đường típ 2, tuổi 40- 70 (54,9 ± 9,2), thời gian trung bình đái tháo đường 9,1 ± 5,4 năm, không có dấu hiệu và triệu chứng của suy tim, không có tiền sử chẩn đoán suy tim. Chúng tôi siêu âm tim để chẩn đoán và phân loại rối loạn chức năng tâm trương thất trái theo tiêu chuẩn năm 2016 của Hội Siêu âm Hoa Kỳ. Kết quả: Chúng tôi ghi nhận 61 BN có rối loạn chức năng tâm trương thất trái (51,7%), giai đoạn I: 41%, giai đoạn II: 45,9%, giai đoạn III: 13,1%. Tỷ lệ nam / nữ = 0,473 (CI 95%; 0,226-0,990), p <0,05. Tỷ lệ rối loạn chức năng tâm trương thất trái gia tăng theo tuổi: Nhóm 40- 49: 41,4%, nhóm 50- 59: 53,2%, nhóm 60- 70: 57,1%. Bệnh nhân có thời gian mắc bệnh ĐTĐ > 10 năm có nguy cơ bị rối loạn chức năng tâm trương thất trái cao hơn so với nhóm mắc bệnh < 5 năm (67,5% so với 38,7%, p <0,05). Huyết áp tâm thu, BMI, HbA1C có vẻ cao hơn ở nhóm rối loạn chức năng tâm trương thất trái (p> 0,05). Kết luận: Rối loạn chức năng tâm trương thất trái xuất hiện sớm và thường xuyên ở bệnh nhân ĐTĐ típ 2. Tỷ lệ rối loạn chức năng tâm trương thất trái liên quan đến giới tính, tuổi, thời gian phát hiện đái tháo đường, BMI, HA tâm thu, HbA1C, ... Chúng ta nên siêu âm tim để phát hiện rối loạn chức năng tâm trương thất trái ở bệnh nhân lớn tuổi, đái tháo đường lâu năm, kiểm soát kém, đặc biệt là nữ.
Eficacia y seguridad del minoxidil oral a bajas dosis en hombres con alopecia androgénica
Authors: Pastore Federico 
Published: May 2021

El minoxidil oral se utiliza solo o combinado con otras terapéuticas para el tratamiento de la alopecia androgénica en hombres y mujeres. La dosis diaria varía entre 0,25 mg y 2,5-5 mg.
En este estudio se utilizó una dosis de 1,25 mg/día en monoterapia durante 24 semanas.
Se incluyeron 32 pacientes de 18 a 45 años, de los cuales 18 (56,2%) nunca habían recibido tratamiento, mientras que en 14 (43,8%) había fracasado el tratamiento previo con minoxidil tópico al 5% dos veces por día como monoterapia o con finasteride oral durante al menos 1,5 a 2 años.
USO DE CÁLCULO ESTEQUIOMÉTRICO PARA AVALIAÇÃO DA PRODUÇÃO DE BIOGÁS OBTIDO DA ÁGUA RESIDUÁRIA DO CAFÉ
Authors: Malaquias Eveline Oliveira , Pereira Junior Antônio Augusto Martins , Silveira Pedro Henrique Poubel Mendonça da , Altoé Leandra , Teles Cláudia Rodrigues 
Published: May 2021

O agronegócio destaca-se por sua participação na economia brasileira e pela expressiva geração de emprego e renda. Neste setor, a atividade cafeeira tem grande importância, sendo o Brasil o maior produtor e exportador mundial deste grão. Porém, seu cultivo gera grande quantidade de resíduos que, se não tratados de maneira adequada, podem ser altamente prejudiciais ao provocar impactos e desequilíbrios ao meio ambiente. Quando o processamento do café é realizado por via úmida, é gerado um efluente com elevado teor orgânico, denominado água residuária do café (ARC). Objetivou-se analisar o potencial da produção de biogás a partir da ARC em uma propriedade rural de Minas Gerais. Foram consideradas amostras tratadas por via úmida, coletadas em uma fazenda que produz café arábica, situada em Conselheiro Pena – Minas Gerais. As amostras foram submetidas a análises físico-químicas e em seguida, avaliada a produção de metano, que compõe o biogás, por cálculo estequiométrico. Verificou-se que a quantidade de metano gerado não foi suficiente para justificar o uso energético da ARC para a propriedade rural estudada. Uma alternativa seria a co-digestão para aumentar a carga orgânica e, consequentemente, o potencial de geração de energia.
PLANIFICACIÓN PARTICIPATIVA Y ACTUACIÓN DE LAS ADMINISTRACIONES PÚBLICAS
Authors: ARNÁEZ ARCE VEGA MARÍA 
Published: May 2021

La sucesión de transformaciones políticas, económicas y sociales en que
estamos inmersos llevan implícita una necesidad inminente de las Administraciones públicas
y del Derecho administrativo en cuanto ordenamiento regulador del funcionamiento,
la organización y la actuación de los poderes públicos. El presente trabajo propone una
aproximación a las características básicas de la planificación administrativa como instrumento
de la denominada nueva gestión pública, así como a su validez como cauce de evaluación
y participación de los ciudadanos en la actuación administrativa, en general y en la
gestión de los intereses públicos en particular.
Azken aldian eraldaketa politiko, ekonomiko eta sozial ugari bizi izan
ditugu jarraian, eta, beraz, administrazio publikoen eta administrazio-zuzenbidearen behar
larria dugu, agintari publikoen funtzionamendua, antolaketa eta jarduera arautzen dituen antolamendu
den heinean. Lan honetan plangintza administratiboaren oinarrizko ezaugarrietara
hurbiltzen gara, gestio publiko berria deritzonaren tresna den heinean, eta herritarrek
administrazio-jardueran, oro har, eta interes publikoen kudeaketan bereziki, ebaluatzeko eta
parte hartzeko bide gisa duen balioa ere aztertzen dugu.
The succession of economic and social transformations we are immersed
into is integral to an impending need of Public Administrations and Administrative Law
as for regulating order for the functioning, organization and action of public powers. The
current work proposes an analysis to the basic features of the administrative planing is an
instrument of the so called new public management as well as to its validity as a channel
for assessment and citizens¿ participation in the administrative action in general, and the
management of public interests in particular.
Tradução Etnogr´´afica: a Viagem e sua Escrita
Authors: Camargo Katia Aily Franco de 
Published: May 2021

O presente artigo tem por objetivo apresentar uma proposta de análise do papel da linguagem/cultura na construção da(s) identidade(s) de um autor-viajante e, também, da identidade do outro. Acredita-se que tal proposta possa ser aplicada à literatura de viajante de uma maneira geral. De caráter eminentemente bibliográfico, tal proposta está baseada na descrição etnográfica enquanto realidade social apreendida a partir do “ver” (Laplantine, La description 1-128; Ferreira, Tradução etnográfica 55-91) e na relação desta com a tradução; nas três categorias de tradução propostas por Jakobson, a saber, intralingual, interlingual e inter-semiótica (63-72); e nas categorias de classificação de itens culturalmente marcados (ICE) elaboradas por Javier Franco (52-78). Como resultado, espera-se que tal proposta seja capaz de identificar as influências na construção da identidade do viajante e de seu “semelhante” estrangeiro.
Entrevista com Alexandre Barbosa de Souza
Authors: Costa Patrícia Rodrigues , Silva Rodrigo D'Avila Braga 
Published: May 2021

Alexandre Barbosa de Souza é escritor, poeta, editor e tradutor. Foi editor na Editora 34, na Cosac Naify e na Biblioteca Azul. É autor de Azul Escuro (Hedra, 2003), Autobiografia de um super-herói (Hedra, 2003) e Livro geral (Companhia das Letras, 2013). Traduz do inglês, francês e espanhol. Entre suas traduções pode-se citar: Moby Dick (Cosac Naify, 2008), de Herman Melville; A crônica dos Wapshot (Companhia das Letras, 2011), de John Cheever; Orgulho e Preconceito (Companhia das Letras, 2011) e Razão e Sensibilidade (Companhia das Letras, 2012), de Jane Austen; Alice através do espelho (SESI-SP, 2018); Só garotos (Companhia das Letras, 2018), de Patti Smith; Anne de Green Gables (Editora Nova Fronteira, 2019), de L. M. Montegomery.
Tradução, Evangelização e Negociação Linguística: uma Exploração Interdisciplinar
Authors: Gallegos Verónica Murillo , D’Amore Anna María , Zimányi Krisztina , Lelis Sara 
Published: May 2021

A tradução da doutrina cristã para as línguas nativas americanas durante a época colonial espanhola apresenta importantes questionamentos para a tradutologia, os quais incitam a análise multi e interdisciplinar. No presente artigo, examinamos o estado da questão da linguística missionária, e do tratamento que foi dado ao encontro cultural que aconteceu entre indígenas nahuas e missionários na Nova Espanha durante o século XVI, desde a filosofia, para realizar uma análise de dois exemplos de tradução com fins de evangelização retirados dos Coloquios de 1524 do frei Bernardino de Sahagún (1986). Relacionamos alguns paralelismos entre o caso colonial e certas iniciativas atuais, e sublinhamos a pertinência de alguns conceitos da linguística, da tradutologia e da filosofia para analisar o problema da comunicação intercultural, assim como o fundamento político e cultural subjacente no caso da Nova Espanha. O tema leva-nos à seguinte pergunta: em que medida essas traduções, realizadas em conjunto por indígenas e missionários, foram um fator relevante de resistência cultural diante dos embates colonialistas de imposição religiosa?
Long noncoding RNA profiling and bioinformatics analysis in the human hepatocellular carcinoma cell line HepG2.2.15 treated with different sex hormones
Authors: Wang Weichuang , Cai Xiangsheng , Yang Xiaorong 
Published: May 2021

IntroductionInfection with viral hepatitis remains a significant risk factor for hepatocellular carcinoma (HCC). To understand the long noncoding RNAs (lncRNAs) expression and gender differences in HCC, we measured differentially expressed lncRNAs and mRNAs, aiming to provide new possible diagnosis and prognostic candidates for HCC.Material and methodsIn our study, we performed lncRNA sequencing to analyze the transcriptome profiles of the human HCC-derived HepG2.2.15 cell line treated with estradiol (E2), testosterone, or untreated. Datasets were analyzed by Coding-Non-Coding Index (CNCI), Coding Potential Calculator (CPC), and other software based on lncRNA levels, such as GO term enrichment analysis and KEGG pathway analysis.ResultsWe identified 1203 lncRNAs and 29565 mRNAs that were expressed differentially. A total of 269 lncRNAs and 9429 mRNAs obtained from HepG2.2.15 cells treated with E2 were upregulated, and 552 lncRNAs and 7196 mRNAs were downregulated compared to the control group. A total of 163 lncRNAs and 7185 mRNAs were upregulated and 219 lncRNAs and 5755 mRNAs were decreased in the testosterone group compared to the untreated group. GO analysis demonstrated that the differentially expressed genes were involved in biological processes, such as cellular processes, cell components, and binding. KEGG functional pathway analysis revealed that the top 20 enriched pathways of antisense target genes included dopaminergic synapse, GnRH signaling pathway, FoxO signaling pathway, and MAPK signaling pathway.ConclusionsThese differentially expressed genes can provide novel insight into the development of more efficient diagnosis and therapeutic strategies for HCC.
Both AA genotype of rs165599 and Val/Val genotype of rs4680 in COMT are associated with an increased risk of recurrence of prostate cancer
Authors: Yang Shixiong , Fu Handong , Liu Xiaobing , Yang Kun 
Published: May 2021

IntroductionCOMT expression was reported to be associated with the recurrence of prostate cancer. Furthermore, it has been shown that rs165599 SNP in the 3’UTR of COMT affects the interaction between miR-138 and COMT, while another polymorphism (rs4680) located in the gene of COMT also affects its expression. Here, we explored the combined effect of rs165599 and rs4680 .Material and methodsKaplan-Meier analysis was performed to analyze the PSA-progression-free survival of prostate cancer patients carrying different genotypes of rs165599 and rs4680 SNPs. IHC and Western blot were used to evaluate the expression of COMT. Real-time PCR was carried out to examine the expression of miR-138 and COMT mRNA. Luciferase assay was performed to explore the inhibitory role of miR-138 in the expression of COMT carrying different genotypes.ResultsThe PSA-progression-free survival was significantly increased in prostate cancer patients carrying the rs165599-AA + rs4680-Val/Val genotype. In concordance with this, the expression of COMT was remarkably elevated in the tissue samples collected from prostate cancer patients carrying the rs165599-AA + rs4680-Val/Val genotype. Luciferase assay demonstrated that COMT-G at rs165599 was effectively suppressed by miR-138 through binding to the 3’ UTR of COMT-G. Furthermore, COMT expression was notably suppressed by miR-138 precursors in primary prostate cancer cells carrying GG genotype at rs165599.ConclusionsThe findings of this study demonstrated that the carriers of AA genotype of rs165599 and Val/Val genotype of rs4680 showed an increased risk of prostate cancer recurrence, and these two polymorphisms may jointly function as a novel biomarker for the prognosis of prostate cancer recurrence.
7 Roles to Create Sustainable Success
Authors: Wijdoogen Carola 
Published: May 2021

Which roles and practices do you adopt to effectively guide businesses towards a sustainable future? And what skills and competencies do you need to establish sustainable transformation? In '7 Roles to Create Sustainable Success', Carola Wijdoogen shares the insights of 25 professionals around the world and her own experiences as Chief Sustainability Officer of Dutch Railways (NS), which she helped transform into a climate-neutral, circular and inclusive railway company. For example, the Netherlands was the first country in the world with trains running on 100% wind power.
The innovative science-based 7 Roles approach is explained using an excellent collection of practices and anecdotes from (among others) Kate Raworth ('Doughnut Economy') and CSOs of companies like Ingka Group, Levi Strauss & Co., Starbucks Coffee Company, Unilever Benelux, Microsoft, Kellogg Company, Interface Europe, KPN, Philips International B.V, DSM, AkzoNobel, Google, Tommy Hilfiger Global/PVH Europe, etc.
The Handbook of Privacy Studies
Authors: Sloot Bart , Groot Aviva 
Published: May 2021

The Handbook of Privacy Studies is the first book in the world that brings together several disciplinary perspectives on privacy, such as the legal, ethical, medical, informatics and anthropological perspective.
Privacy is in the news almost every day: mass surveillance by intelligence agencies, the use of social media data for commercial profit and political microtargeting, password hacks and identity theft, new data protection regimes, questionable reuse of medical data, and concerns about how algorithms shape the way we think and decide. This book offers interdisciplinary background information about these developments and explains how to understand and properly evaluate them.
The book is set up for use in interdisciplinary educational programmes. Each chapter provides a structured analysis of the role of privacy within that discipline, its characteristics, themes and debates, as well as current challenges. Disciplinary approaches are presented in such a way that students and researchers from every scientific background can follow the argumentation and enrich their own understanding of privacy issues.
Making Shift Happen
Authors: Wit Margareth ,   Academica University of Applied Sciences, Hills Jonathan 
Published: May 2021

Leadership is learnable. Furthermore, future developments within our organizations will be strongly influenced by our leadership effectiveness. In ten steps Margareth de Wit describes how, as a leader, you can train yourself to achieve desired transitions within your organization. Educated at INSEAD and Wharton, Margareth de Wit has a long and rich experience working at the top of international companies in the USA, India, the UK, and Africa, providing intensive leadership sessions to CEOs, commissioners, managers, and directors.
Margareth de Wit has inspired hundreds of professionals within the education sector to see themselves as playing the central role in providing better education through intelligent collaboration in self-managing school teams. Her experiences show that systematic attention to leadership and group dynamics creates organizations that are both successful and future-proof. Providing striking examples from her broad practice and experience, historical comparisons, human interactions, analytical schemes, and evidence-based methods, de Wit paints a picture of the road that leads to effective leadership. While this transition is never finished, it is nevertheless one that always leads to both personal and organizational improvement.
Globalization, Nationalism, and Music Education in the Twenty-First Century in Greater China
Authors: Ho Wai-Chung 
Published: May 2021

Globalization, Nationalism, and Music Education in the Twenty-First Century in Greater China examines the recent developments in school education and music education in Greater China – Mainland China, Hong Kong, and Taiwan – and the relationship between, and integration of, national cultural identity and globalization in their respective school curriculums. Regardless of their common history and cultural backgrounds, in recent decades, these localities have experienced divergent political, cultural, and educational structures. Through an analysis of the literature, official curriculum documents, approved music textbooks, and a survey questionnaire and in-depth interviews with music teachers, this book also examines the ways in which policies for national identity formation and globalization interact to complement and contradict each other in the context of music education in respect to national and cultural values in the three territories.
Wai-Chung Ho’s substantive research interests include the sociology of music, China’s education system, and the comparative study of East Asian music education. Her research focuses on education and development, with an emphasis on the impact of the interplay between globalization, nationalization, and localization on cultural development and school music education.
Sistem Informasi Manajemen Zakat (SIMZ) Berorientasi Objek Dengan Pemanfaatan UML (Unified Modeling Languange)
Authors: Mulyawan Alif Rizqi , Basri Hasan , Alfarizi Salman , Ichsan Nurul , Gunawan Deni 
Published: May 2021

Abstrak: Pada dasarnya fungsi komputer digunakan sebagai media untuk menyimpan data yang didalamnya terdapat banyak program aplikasi yang dapat mempermudah serta menunjang suatu pekerjaan manusia. Pada bagian administrasi sebuah lembaha amil zakat di daerah Karawang dalam proses pengolahan data zakat, laporan-laporan serta penyimpanan data masih dilakukan secara manual belum ada aplikasi khusus untuk pengelolaannya. Adanya kesalahan penginputan data serta ketidak akuratan data sangat mungkin terjadi. Untuk mengatasi permasalahan tersebut, perancangan sebuah program merupakan solusi terbaik untuk pemecahan masalah ini. Ketersediaan formulir penginputan data dan media penyimpanan yang terpusat dalam database, maka dapat membuat aplikasi dalam pengelolaan zakat menjadi lebih akurat, sehingga akan membuat pengelolaan zakat menjadi lebih berkualitas. Aplikasi SIMZ mempunyai tampilan yang sederhana dan interaktif namun dapat mengolah data yang sangat baik dan dapat memenuhi kebutuhan sistem, sehingga pengguna dapat dengan mudah mengguanakannya. Adapaun dalam perancangan sistem informasi zakatyang dibuat adalah berorientasi objek.

Kata kunci: berorientasi objek, manajemen zakat, sistem informasi.

Abstract: Basically, the function of a computer is used as a medium for storing data in which there are many application programs that can simplify and support human work. In the administrative section of an amil zakat institution in the Karawang area, the processing of zakat data, reports, and data storage is still done manually, there is no special application for its management. The existence of data input errors and data inaccuracies are very likely to occur. To solve this problem, designing a program is the best solution for solving this problem. The availability of data input forms and centralized storage media in a database can make the application of zakat management more accurate so that it will make zakat management more qualified. The SIMZ application has a simple and interactive interface but can process data very well and can meet system requirements so that users can easily use it. As for the zakat information system design made is object-oriented.

Keywords: information system, object-oriented, zakat management.
Sistem Informasi Pendukung Pengadaan Barang Dan Jasa Pada Inspektorat Provinsi DKI Jakarta
Authors: Choeruman Aditya Fakhri , Safitri Nadya , Fauziah Nofia Filda 
Published: May 2021

Abstrak: Dalam pengadaan barang atau jasa pada Inspektorat DKI Jakarta dilakukan pada sistem E-Katalog, namun sistem tersebut tidak mengakomodir keseluruhan prosesnya. Selain itu, pembuatan dokumen pendukung masih dibuat secara manual menggunakan Microsoft Office sehingga dinilai tidak efektif, efisien dan berkasnya menjadi rentan hilang. Serta kesulitan dalam pembuatan laporan pengadaannya dikarenakan berkas hilang dan berkas yang disimpan tidak tersentralisasi. Metode yang dipakai dalam mengembangkan dengan Rapid Application Development (RAD). Sistem informasi pengadaan menghasilkan dokumen pengadaan lebih terstruktur dan instan dalam mengolah hasil pengadaan dalam bentuk laporan. Hasil pengembangan ini menciptakan alur kerja yang lebih tertib dan terdokumentasi dengan baik, serta memberikan pengamanan terhadap data pengadaan. Dengan adanya sistem informasi ini, proses pengadaan barang dan jasa pada Inspektorat Provinsi DKI Jakarta menjadi lebih tertib.

Kata kunci: DKI Jakarta, e-katalog, pengadaan, RAD, web.

Abstract: In procuring goods or services at the DKI Jakarta Inspectorate, the E-Catalog system is carried out, but the system does not accommodate the entire process. In addition, supporting documents are still created manually using Microsoft Office, so they are considered ineffective, efficient and the files are vulnerable to loss. As well as difficulties in making procurement reports because the files are lost and the files that are stored are not centralized. The method used in developing with Rapid Application Development (RAD). Procurement information systems produce more structured and instant procurement documents in processing procurement results in the form of reports. The results of this development create a more orderly and well-documented workflow and provide security for procurement data. With this information system, the process of procuring goods and services at the Inspectorate of DKI Jakarta Province becomes more orderly.

Keywords: DKI Jakarta, e-katalog, procurement, RAD, web.