bluuebunny/crossref_metadata_2025_split huggingface dataset:
A clinico-mycological spectrum of superficial mycoses of scalp in pediatric population
Authors: Zeeshan Faiza , Uddin Fakhur , Khan Bahram , Zehra Talat , Razzak Sadaf , Irshad Zareen 
Published: January 2021

Objective: A clinico-mycological study was conducted to assess the profile of dermatophytes and non-dermatophytes in patients with superficial mycoses of scalp.
Methods: This Descriptive cross sectional study was conducted at Department of Microbiology, Basic Medical Sciences Institute, in collaboration with Department of Dermatology, Jinnah Postgraduate Medical Centre, Karachi. The study was carried out from May 2019 to September 2019. A total of 114 children were enrolled in the study having a clinical diagnosis of superficial mycoses of scalp. The hair specimens and scales from the scalp were collected. The specimens were processed for wet mounts (KOH and CFW staining) and mycological culture. .
Results: The most common clinical presentation was found to be dermatophytoses (28%). Non-dermatophytoses was seen in 16.1% cases, while 55.2% cases were culture negative. The most common isolated dermatophyte was Trichophyton violaceum (35.4%), while among non-dermatophyte molds, Aspergillus spp accounted for 45% of cases.
Conclusion: The unambiguous diagnosis of scalp mycoses can be made by mycological culture and conventional techniques like KOH mounts and CFW staining.
Keywords: Calcoflour white stain, Dermatophytes, KOH mount, Tinea capitis
Predictive Efficacy of Haematological Biomarkers in COVID-19 infection
Authors: Nadeem Ikram,Asma Nafisa, Rabia Anjum,Naeem Akhter Nadeem Ikram,Asma Nafisa, Rabia Anjum,Naeem Akhter 
Published: January 2021

Introduction: The ongoing Corona Virus Pandemic is linked with high rates of morbidity and mortality globally. Early and effective predictors of clinical outcomes are urgently required to develop effective management protocols.Objective: To investigate the predictive efficacy of haematological biomarkers in Covid -19 infectionMethods: Blood samples were drawn from COVID‐19 infected pneumonia patients. Baseline clinical information was collected and quantification of hemostatic variable was done. Laboratory data both groups expired and recovered were compared using t- test, Mann Whitney- U test, chi squared-test and Kruskal Wallis test. Multivariate regression analysis was performed to determine the independent contribution of haematological variable in Covid19 related mortality. Receiver operating characteristic curve were drawn to find the predictive efficacy of significantly related parameters.Results: Out of 191 patients 68.1% were male. D‐dimer (median 800 ng/mL; IQR 200‐3200) and NLR (median 10.40; IQR 3.20-22.80) were found to be predominantly raised and significantly correlated with Covid mortality in multivariate regression analysis. The optimum cutoff value of D-dimer to predict in-hospital mortality was 450 ng/ml with a sensitivity of 71.6% and a specificity of 95.8%. The optimum cutoff value of NLR to predict in-hospital mortality was 5.450 with a sensitivity of 70.1% and a specificity of 71%.Conclusion: D-dimer and NLR could be used as the signiﬁcant indicators in predicting the mortality of COVID-19.
Les paradoxes dans un établissement de santé : reconstruire du sens par l’innovation managériale
Authors: Albert-Cromarias Anne , Santos Catherine Dos 
Published: January 2021

Les établissements de santé connaissent depuis plusieurs années un tournant gestionnaire qui se traduit par une recherche de rationalisation et un risque de focalisation sur la dimension économique. Dans ce contexte, ils font face à des tensions paradoxales qui mettent à mal le sens de leur action. Notre problématique est alors la suivante : peut-on répondre aux paradoxes d’un établissement de santé par l’innovation managériale en s’appuyant sur la (re)construction de sens ? La recherche s’appuie sur l’étude d’un Centre de Lutte Contre le Cancer (CLCC) et est fondée sur une analyse documentaire et des entretiens à visée compréhensive. Les résultats montrent que l’innovation managériale comme réponse aux paradoxes permettrait de recréer collectivement du sens.
Développer les talents des non-cadres par une politique d’intégration des primo-arrivants : le cas d’une entreprise publique en mutation
Authors: Garcia Jean-François , Brillet Franck , Montargot Nathalie 
Published: January 2021

Dans les pratiques organisationnelles, le management des talents est souvent associé au personnel cadre d’organisations privées et relié à des dispositifs issus de la GPEC. Cet article propose de questionner ce lien traditionnel. Les auteurs interrogent qualitativement la relation dyadique entre développement des talents non-cadres et politique d’intégration d’une entreprise publique. Les résultats de l’étude montrent qu’en permettant aux primo-arrivants d’être acteurs de leur propre développement, ce dispositif renouvelle « l’offre RH » en matière d’accompagnement des talents.
Augmenter les raisonnements constructifs : une compétence transversale sous-utilisée par les managers pour innover
Authors: Vachon Marc 
Published: January 2021

Dans le cadre d’une recherche reliant la gestion des ressources humaines et l’innovation, nous posons la question suivante : quelle compétence transversale les managers doivent-ils utiliser pour innover ?… En réponse, nous préconisons aux managers d’augmenter les raisonnements constructifs, qui sont presque deux fois moins utilisés que les routines défensives. Cette préconisation nous a conduits à créer une formation à l’utilisation des raisonnements constructifs.
Reporting volontaire en matière de responsabilité sociale : un effet contrasté de l’assurance RSE
Authors: Lajmi Amira , Nekhili Mehdi , Nagati Haithem , Paché Gilles 
Published: January 2021

L’article analyse le rôle modérateur que joue l’assurance RSE, en tant que mécanisme de gouvernance axé sur le développement durable, dans la relation entre le reporting volontaire en matière de responsabilité sociale et la valeur de marché de l’entreprise. À partir des données recueillies auprès d’un échantillon d’entreprises françaises du SBF 120 entre 2001 et 2011, les résultats indiquent que la valeur de la communication volontaire d’informations relatives à la RSE est perçue négativement et que le recours à une assurance RSE par un organisme tiers indépendant n’est pas nécessairement pertinent. Les auteurs constatent toutefois que les actionnaires ne portent pas le même jugement sur chaque dimension du reporting RSE, et ils ne perçoivent l’intérêt de recourir à une vérification sociétale qu’en cas de doute sur la crédibilité des informations communiquées.
La digitalisation du recrutement post-bac : ses enjeux et ses limites. Peut-on parler d’innovation ?
Authors: Luangsay-Catelin Carine , Roybier-Mtanios Rajaa 
Published: January 2021

L’objet de la présente recherche est d’étudier comment par son rôle restructurant, le numérique, a remodelé le processus de recrutement des étudiants à destination des formations Post-Bac. Aussi, après avoir présenté une brève revue de la littérature sur les transformations du service public, en mettant en évidence les enjeux de la digitalisation, nous nous tournerons sur le processus de recrutement des étudiants dans l’enseignement supérieur en France. En effet, nous examinerons en quoi la mise en place et les adaptations de ce dernier peuvent constituer une innovation permettant de renforcer l’efficacité et l’efficience du service public ?
Quel modèle d’émergence pour les start-up des éco-industries : David un futur Goliath ou David avec Goliath ?
Authors: Petzold Stéphanie , Fonrouge Cécile 
Published: January 2021

Dans les industries verdissantes, des start-up, tels des "David" tentent de trouver leur place à côté des "Goliath" qui mettent du vert dans leur stratégie. Quel modèle d’émergence ces start-up sont-elles en mesure d’adopter? Pour répondre à cette question deux lectures complémentaires sont proposées : celle en termes de design dominant et celle de type évolutionniste. Un cas de l’éco-industrie en France permet d’étudier en profondeur le cheminement stratégique d’une start-up. Les résultats mettent en évidence des facteurs de contingence qui pousseraient les start-up des éco-industries soit vers un modèle soit vers l’autre.
L’entreprise, la comptabilité et le droit : enjeux, risques et perspectives au regard de la loi Pacte
Authors: Bourgeois Clémentine , Ouvrard Stéphane 
Published: January 2021

Suite à la publication de la loi Pacte 1 , la vision actionnariale de la gouvernance véhiculée par les IFRS 2 va-t-elle évoluer ? En ouvrant la voie à un modèle de gouvernance élargi, la loi Pacte et les différents rapports qui l’ont précédé réhabilitent le rôle social et sociétal de l’entreprise. Suivant ses propres objectifs, l’entreprise incarne un « objet d’intérêt collectif » (Notat et Sénard, 2018).
Pôle d’activité médicale et coopération médico-économique : une nouvelle structure organisationnelle à l’épreuve de l’incertitude des préférences
Authors: Vallejo Jimmy 
Published: January 2021

Depuis plusieurs années, l’hôpital public français est sujet à un tournant gestionnaire et à la mise en place depuis 2005 d’une nouvelle gouvernance : la création des pôles d’activité́ médicale. L’idée est de rapprocher les logiques gestionnaires et médicales, à travers le développement d’un monde médico-économique, en favorisant la coopération entre ces deux logiques. L’objectif de cette recherche est de s’interroger sur les conditions de la coopération entre gestionnaires et médecins à travers les pôles, à partir d’une mobilisation innovante du cadre théorique de l’anarchie organisée, et de l’étude de cas d’un grand CHU.
Assessment of job satisfaction and quality of life among practicising pediatric intensivists of India
Authors: Prasad V. S. V. , Dayal Anjul 
Published: January 2021

Introduction:
Pediatric intensive care specialty is a challenging field. This exposes the pediatric intensivist to various levels of stress at different stages of their career. The various precipitating factors for stress are prolonged working hours, decreased quality time with family, unsatisfactory remuneration, and increasing medicolegal litigations and physical, psychological stress, and property damage caused by unhappy families.

Aim:
The study was conducted to assess the quality of life, working patterns as well as socioeconomic wellbeing among pediatric intensivists working in Indian pediatric intensive care units (PICUs) in the private sector, public sector, and charitable institutions.

Methods:
A nationwide survey was performed in 2019 among the pediatric critical care fraternity across India to ascertain and enquire about several aspects of their work, careers, and personal lives with a Google form request with preformed questions and single answer options for this survey.

Results:
A total of 181 responses were received. About one-third (34%) chose this pediatric specialty for its challenging nature. Close to 40% of respondents were engaged in practice of other specialties of pediatrics apart from pediatric intensive care. Professionally, 86% of pediatric intensivists were satisfied with their work. More than half of the respondents (62%) felt that aggression against hospitals and health-care personnel was worrisome and these incidents affected their personal health with increased stress and subconscious fear.

Conclusions:
This survey revealed that most pediatric intensivists are satisfied with their chosen profession. Stress has been documented as a significant issue with violence in health-care settings being one of the most worrying aspects.
Can serum ferritin be employed as prognostic marker of pediatric septic shock and severe sepsis?
Authors: Sarkar Mihir , Roychowdhury Satyabrata , Uz Zaman Mohammad Asraf , Raut Sumantra , Bhakta Subhajit , Nandy Mousumi 
Published: January 2021

Introduction:
Serum ferritin has emerged as an independent marker predicting the outcome of critically ill patients. The cutoff value of ferritin in predicting mortality in septic children is not well established.

Objective:
The aim is to determine the cutoff value of ferritin which is, best predictive of mortality in patients with age from 1 month to 12 years with a diagnosis of septic shock or severe sepsis and to evaluate correlation with PRISM III score, and Pediatric Logistic Organ Dysfunction score (PELODS).

Materials and Methods:
A prospective observational study was conducted over a period of 2 years at pediatric intensive care unit (PICU) in children with age from 1 month to 12 years with septic shock or severe sepsis and PICU stay >24 h. Children with autoimmune diseases, primary hemophagocytic lymphohistiocytosis, blood transfusion in the past 4 months, known malignancies and immunosuppressive treatment were excluded. PRISM-III and PELODS were assessed to predict the risk of mortality and severity of disease. The highest value of ferritin was taken to draw area under the curve using receiver operating characteristic curve and determine cutoff value.

Results:
Out of 176 children of septic shock or severe sepsis, 132 were included in the study. Mortality rate was 22.7% (n = 30). PRISM III and PELODS-2 were significantly high in nonsurvivors (P ≤ 0.001 and 0.006, respectively). The cutoff value of ferritin at 2375 ng/dl had sensitivity 96.7% and specificity 88% to predict mortality. Ferritin level was positively correlated to the PRISM III and PELODS, correlation coefficient 0.447 and 0.601, respectively.

Conclusion:
Serum ferritin values ≥2375 ng/mL in children with septic shock, and severe sepsis was significantly associated with mortality. Its performance had a good correlation with PRISM III and PELODS.
Compliance of Mumbai-based clinical trial sites with the Quality Council of India guidelines and evaluation of the challenges faced by the investigators
Authors: Figer Brinal , Gogtay Nithya Jaideep , Thatte Urmila Mukund 
Published: January 2021

Purpose:
A committee chaired by Dr. Ranjit Roy Chaudhary suggested accreditation of investigators, sites and ethics committees to improve the quality of trial conduct in the country. Prior to accreditation, understanding the challenges faced at the sites by investigators could help define the extent of the problem and identify potential solutions. Hence, we conducted the present study.

Methods:
Institutional Ethics Committee approval and written informed consent was obtained prior to enrolment. A checklist and a questionnaire was used to assess compliance to Quality Council of India (QCI) standards and the challenges faced by the sites and investigators respectively. Mumbai based investigators listed in the Clinical Trial Registry of India (CTRI) were enrolled. The responses obtained were analysed descriptively. The responses to each question in the checklist were calculated as a proportion and response to each item in the questionnaire was calculated in frequency and percent frequency. All the analysis was done using Microsoft Excel version 2013.

Results:
A total of 30 investigators from 69 clinical trial sites agreed to participate. We found that over 80% of the sites complied with standards recommended by the QCI guideline. The most frequently reported issues at the site were lack of space for archival (25%), no System to evaluate adequacy of training (31.81%) and lack of understanding of the technical language of the informed consent form (39.02%).

Conclusion:
There is a need of coordinated effort between all the stakeholders to improve the clinical trial conduct at the site.
Vaccination status and Seroprevalence of Hepatitis B surface Antigen among Health Care Workers in Taiz, Yemen Republic
Authors: ALI Waheed , Thabit Riyadh Abdulmajid , Alkhulaidi Mansoor , Ahmed Ahmed Abdullah 
Published: January 2021

Background: Exposure to Hepatitis B virus (HBV) infection is one of the most common occupational diseases among the providers of the health care services. During the course of their clinical work; Health Care Workers (HCWs) are at risk of acquitting HBV infection or transmitting it to their patients. Vaccination for medical personnel against HBV in Yemen Republic is recommended but not strictly enforced. Detection of the viral hepatitis B surface antigens (HBsAg) is one of the accurate and cheap methods to assess HBV prevalence. This method is used in this study to assess HBV prevalence among HCWs in Taiz; to in order to improve on methods of interventions to control this infection among them. Objectives: The objective of this study was to assess the vaccination status and the seroprevalence of HBsAg among HCWs in Taiz; Yemen republic. Methods: This cross sectional study was conducted through the period between January and March, 2018, and from April and July, 2019, in the part of Taiz City; Yemen Republic belonging to legitimate authorities. 362 HCWs were included in this study and are selected through repeated casual visits to hospitals and medical centers. A questioner was made to get information on the participants’ characteristics and their vaccination status, medical hestory and risk factors for HBV transmission. Five ml venous blood was then collected from every participant to assess HBsAg. Results: the overall vaccination percentage was 21.54% (27.5% in male and 17.9% of female). The seroprevalence of HBsAg was 2.76%, all vaccinated participants were HBsAg negative. Needle stick and sharp object injury was an important risk factor of HBV infection.
A Complexidade no Fenômeno do Conflito
Authors: Moreira Katia Denise , Rodrigues Luci Mari Aparecida , Costa Alexandre Marino 
Published: January 2021

Considerado o pressuposto de que o fenômeno do conflito apresenta bases epistemológicas distintas, com vertentes que ou o refutam ou o consideram essencial para a evolução humana, e, ainda, que essa questão paradoxal se alinha às concepções da teoria da complexidade, este estudo tem por objetivo analisar, a partir de bases epistemológicas, a associação entre o fenômeno do conflito e o paradigma da complexidade. Nessa direção, buscou-se o alinhamento entre os elementos estruturantes de uma e outra teoria; ação que permitiu alcançar como resultado a concepção de que o conflito tem natureza complexa devido a sua dinamicidade, não linearidade, ambiguidade, reconstrutivismo, dialogicidade evolutiva, irreversibilidade e intensidade. Concluiu-se que o fenômeno é considerado essencial quando consolidado como elemento contrário à estagnação e, consequentemente, promotor da evolução.
Antioxidant, anti-inflammatory, analgesic and anti-proliferating activities of Grewia heterotricha Mast.
Authors: Usha B. , Jyothsna Karanth , Chandrashekhar G. Joshi 
Published: January 2021

Introduction and Aim: Plants are considered to be novel source of active compounds having pharmacological properties and help in the development of therapeutic agents. Hence, this study was undertaken to evaluate the antioxidant, anti-inflammatory, analgesic and anti-proliferating activity of aqueous and methanolic leaf extracts of Grewia heterotricha Mast.
Materials and Methods: The aqueous and methanolic leaf extracts of the plant were assessed for their in-vitro antioxidant activity by DPPH radical scavenging activity, in-vivo anti-inflammatory activity by carrageenan induced rat paw edema method, in-vivo analgesic activity by acetic acid-induced writhing test and in-vitro anti- proliferating activity by MTT assay.
Results: The methanolic extract had shown very significant DPPH radical scavenging activity with IC50 value 98.95?g/ml than aqueous extract and showed a significant reduction in the paw volume of rats at the concentration of 100 mg/kg body weight indicating potent anti-inflammatory activity compared with the reference standard Diclofenac sodium. Both the extracts showed significant analgesic effect (p<0.001) in acetic acid-induced pain models in a dose dependent manner. The methanolic extract showed higher analgesic activity compared to aqueous extract by inhibiting the pain indicated by a decrease in the number of writhes. In addition, both the extracts showed a decrease in MCF-7 cell viability at the concentration of 550µg/ml. Compared to the aqueous extract, MEGH has shown more cytotoxic effect on the cancer cell lines.
Conclusion: The results suggest that both aqueous and methanolic extracts of Grewia heterotricha Mast. leaves possess potent antioxidant, analgesic, anti-inflammatory and anti-proliferating properties, which supports the use of the plant in traditional medicine. Further investigation is required to illuminate on its active compounds.

Keywords: Analgesic; anti-inflammatory; DPPH; cytotoxic.
Computer-aided structural analysis and design of the 37-storey Los Angeles Bonaventure Hotel
Authors: Nicoletti J. P. , Jhaveri D. P. , Emkin L. Z. , Mesley R. C. 
Published: January 2021

The paper briefly describes and summarizes the computed-aided analyses and design for a complex convention hotel structure in Los Angeles. Seismic analyses, upon which structural steel sizing was based, were both static and dynamic. The latter were carried out for two postulated levels of seismic ground motion, and included both response-spectrum and time-history methods.
Columns, column splices and joint details at beam to column connections were designed using a computer program.
From the Social Museum to the Digital Social Museum
Authors: Más José M. , Monfort Abel 
Published: January 2021

Main topic / subject: The goal of the article is to organize the conceptual evolution between the social museum and the digital social museum, a fundamental conceptual change that will imply a different form of management and that considers the latest technologies applied to the museum experience.

Logical development of the subject: For the development of this conceptual proposal, the paper starts from a series of fundamental texts that describe the current situation of experience management in museums; it carries out a critical review of the concepts of the traditional museum and the social museum and with data and examples the paper proposes the use of the concept of the digital social museum.

Author’s point of view and contributions: The article contributes to the definition of the digital social museum. It expands the concept of the social museum and gives a fundamental value to the impact of new technologies and social networks as an integral part of the museum experience and management.

Implications and conclusions: Museum institutions should work in a much more inclusive and participatory manner, thus giving way to an evolution that begins in the early twentieth century and is called the social museum. New technologies offer great potential for the achievement of these goals of participation and dialogue, leading to a new concept of the digital social museum. Through this paper we reflect on how new technologies contribute to understand museum management under the principles of the digital social museum.