bluuebunny/crossref_metadata_2025_split huggingface dataset:
Graphene Oxide/Hexylamine Superlattice Field‐Effect Biochemical Sensors
Authors: Huang Yingqi , Yin Shujia , Huang Yujia , Zhang Xiaoyan , Zhang Weizhe , Jiang Guangya , Zhu Hongwei , Wan Chunlei , Fu Wangyang 
Published: February 2021

AbstractThe bulky assembly of 2D materials is highly desired for macroscopic applications, but it is still challenging to access the exceptional properties of 2D materials owing to their spontaneous aggregation. Here, to facilitate the access of the field‐effect sensing abilities of semiconducting 2D materials in bulk quantities, 3D hybrid superlattices of alternating graphene oxide (GO) and hexylamine molecular layers are constructed. Strikingly, the fabricated flexible GO/hexylamine superlattice exhibits a “V”‐shaped ambipolar field‐effect transfer characteristic under electrolyte gating, with exceptional sensing ability to pH value and DNA molecules in buffer solutions. In contrast, GO paper prepared by annealing the hybrid superlattices exhibits neither field‐effect nor sensing responses to various analytes, highlighting the essential role that hexylamine plays in modulating the GO/hexylamine superlattice to enable a wider interlayer spacing for biomolecules transportation in the internal graphene layer. These achievements, along with stable electrical and sensing performance under mechanical stress of the 3D hybrid superlattices, highlight the unique potential of flexible graphene 3D hybrid superlattices for biochemical applications by overcoming multilayer aggregation.
Electrically Tunable Surface Acoustic Wave Propagation at MHz Frequencies Based on Carbon Nanotube Thin‐Film Transistors
Authors: Shen Chen , Lu Shiheng , Tian Zhenhua , Yang Shujie , Cardenas Jorge A. , Li Junfei , Peng Xiuyuan , Huang Tony Jun , Franklin Aaron D. , Cummer Steven A. 
Published: February 2021

AbstractSurface acoustic waves (SAWs) that propagate on the surface of a solid at MHz frequencies are widely used in sensing, communication, and acoustic tweezers. However, their properties are difficult to be tuned electrically, and current devices suffer from complicated configurations, complicated tuning mechanisms, or small ranges of tunability. Here a structure featuring a thin‐film transistor configuration is proposed to achieve electrically tunable SAW propagation based on conductivity tuning. When a DC gate voltage is applied, the on‐site conductivity of the piezoelectric substrate is modulated, which leads to velocity and amplitude tuning of SAWs. The use of carbon nanotubes and crystalline nanocellulose as the channel and gate materials results in high tuning capacity and low gate voltage requirement. The tunability is manifested by a 2.5% phase velocity tuning and near 10 dB on/off switching of the signals. The proposed device holds the potential for the next generation SAW‐based devices.
A Novel Dual‐Crosslinked Functional Hydrogel Activated by POSS for Accelerating Wound Healing
Authors: Yang Cheng , Huang Hai , Fan Shicai , Yang Chengliang , Chen Yuhui , Yu Bo , Li Wenqiang , Liao Jianwen 
Published: February 2021

AbstractHydrogel dressings have attracted extensive attention owing to the similarity in their softness to that of the extracellular matrix, adjustability of physicochemical properties, and ability to remain moist even at the wound site. However, developing composite hydrogel with excellent mechanical behavior, adhesiveness to tissues, good biocompatibility, long‐term antibacterial properties, and enhanced vascularization capacity continues to be a great challenge. Herein, a novel nanocomposite hydrogel based on the photo‐cross‐linking of poly(ethylene glycol)diacrylate (PEGDA), thiolated chitosan (TCS), and modified polyhedral oligomeric silsesquioxane (POSS) nanoparticles is designed. Moreover, silver ions (Ag+) are loaded into the system via dynamic coordination of Ag–S. The resultant PEGDA/TCS/POSSP@Ag hydrogel presents high toughness, strength, and good tissue adhesiveness and facilitates the attachment and proliferation of human umbilical vein endothelial cells (HUVCEs) in vitro. As a controlled release carrier of the bacteria‐killing activity of Ag+, the composite system achieves controlled release of Ag+ and good antibacterial activity. Further in vivo experiments demonstrated that the PEGDA/TCS/POSSP@Ag scaffolds significantly promote skin regeneration by reducing inflammation and inhibiting infection, a rat model with full‐thickness skin defects verified its ability to stimulate microvascular formation due to activation of POSS. Thus, the multi‐functional nanocomposite hydrogel is a highly promising dressing material for wound healing.
Graduate medical education tool kit for the Supplemental Offer and Acceptance Program: Navigating the National Resident Matching Program supplemental offer assistance program
Authors: Vance Steve , Figg Bethany J. , Wagner Mary Jo 
Published: February 2021

AbstractMore residency training programs are involved in the National Resident Matching Program (NRMP) Supplemental Offer and Acceptance Program (SOAP) than in the past, which is unanticipated by many. Without an action plan in place, the SOAP process can be chaotic and could result in offers to incompletely vetted residency applicants and unfilled residency slots. Faced with this challenge, it is important that programs have a unified, clear process and action plan for the SOAP. Our instution has created a SOAP tool kit that documents our strategies, scripts, and timelines in preparation of SOAP. The success of our approach has been gauged by the positive response from the key stakeholders who found this easy to use without significant advanced training. Faculty and staff noted significant efficiencies and improvements in the process when using the SOAP tool kit. Applicants indicated that the process was more organized than other residency programs they interacted with during the SOAP week. We anticipate that the use of the documents in the SOAP tool kit will help other training programs improve their performance during the SOAP process.
Following Electroenzymatic Hydrogen Production by Rotating Ring–Disk Electrochemistry and Mass Spectrometry**
Authors: Khushvakov Jaloliddin , Nussbaum Robin , Cadoux Cécile , Duan Jifu , Stripp Sven T. , Milton Ross D. 
Published: February 2021

AbstractGas‐processing metalloenzymes are of interest to future bio‐ and bioinspired technologies. Of particular importance are hydrogenases and nitrogenases, which both produce molecular hydrogen (H2) from proton (H+) reduction. Herein, we report on the use of rotating ring–disk electrochemistry (RRDE) and mass spectrometry (MS) to follow the production of H2 and isotopes produced from deuteron (D+) reduction (HD and D2) using the [FeFe]‐hydrogenase from Clostridium pasteurianum, a model hydrogen‐evolving metalloenzyme. This facilitates enzymology studies independent of non‐innocent chemical reductants. We anticipate that these approaches will be of value in resolving the catalytic mechanisms of H2‐producing metalloenzymes and the design of bioinspired catalysts for H2 production and N2 fixation.
Structural biomaterials engineered from lignocellulosic agricultural waste
Authors: Kárpáti Zoltán , Kun Dávid , Fekete Erika , Móczó János 
Published: February 2021

AbstractMilled sunflower husk was added to three types of polyolefins (polypropylene, low‐density and high‐density polyethylene) in a wide composition range. Composite series were prepared with or without maleic anhydride‐grafted polyolefin coupling agents to investigate the effect of coupling on the mechanical properties and micromechanical deformation processes. Several independent approaches were followed to estimate interfacial adhesion qualitatively and quantitatively, respectively. The results show that interfacial adhesion is significantly improved in the presence of a coupling agent. As a result, coupling changes the dominant deformation process from matrix/filler debonding to the fracture of sunflower husk particles. Milled sunflower husk can enhance significantly the modulus of polyolefins; however, elongation‐at‐break values are very small, especially at larger filler content, which represents the largest obstacle of practical application.
“Striking out on your own”—A study of research information management problems on university campuses
Authors: Stvilia Besiki , Lee Dong Joon , Han Na‐eun 
Published: February 2021

AbstractHere, we report on a qualitative study that examined research information management (RIM) ecosystems on research university campuses from the perspectives of research information (RI) managers and librarians. In the study, we identified 21 RIM services offered to researchers, ranging from discovering, storing, and sharing authored content to identifying expertise, recruiting faculty, and ensuring the diversity of committee assignments. In addition, we identified 15 types of RIM service provision and adoption problems, analyzed their activity structures, and connected them to strategies for their resolution. Finally, we report on skills that the study participants reported as being needed in their work. These findings can inform the development of best practice guides for RIM on university campuses. The study also advances the state of the art of RIM research by applying the typology of contradictions from activity theory to categorize the problems of RIM service provision and connect their resolution to theories and findings of prior studies in the literature. In this way, the research expands the theoretical base used to study RIM in general and RIM at research universities in particular.
Mastery criteria and the maintenance of skills in children with developmental disabilities
Authors: Pitts Laura , Hoerger Marguerite L. 
Published: February 2021

AbstractBehavior analysts typically set a criterion for correct responding to determine when a skill is considered mastered. Practitioners often preset the criteria arbitrarily as there is little empirical evidence about the effects of differing mastery criteria on the maintenance of skills. The aim of the current study was to evaluate the effects of differing mastery criteria on skill maintenance. The impact of 80%, 90%, and 100% correct responding on the maintenance of sets of skills taught during discrete trial teaching was evaluated. Four children aged between 5‐ and 9‐years‐old with a diagnosis of Autism Spectrum Disorder participated in the research. Participants were taught to recognize words. Sets of words were taught until each of the three criteria were met, skill maintenance was probed after 1 week, and again once per week for another 3 weeks. Results demonstrated that skills were maintained at a response accuracy similar to the mastery criteria employed; with mastery criteria of 100% reliably producing higher levels of accurate responding during maintenance than a mastery criteria of 80% and 90%.
Investigating teachers' enactment of engineering design practices in a CAD simulation‐enhanced learning environment
Authors: Dasgupta Chandan , Magana Alejandra J. , Kirkham Lisa 
Published: February 2021

AbstractEngineering design problems are ill‐structured, and as a result, learners find it challenging to engage productively in relevant practices of analysis, synthesis, and evaluation for solving problems in the domain. Teachers find it particularly difficult to effectively support such engagement. Thus, there is a need to understand how teachers orchestrate their classrooms for maximizing opportunities for students to engage in these practices. In this paper, we use the case study methodology to investigate how teachers materialize and enact engineering design practices in a CAD simulation‐enhanced learning environment. Three teachers (cases) provide evidence for the following orchestration techniques—scaffolding development of students' expertise via teacher‐guided decomposition of problem space, apriori teacher‐led parameter determination, and student‐generated contrasting cases. These techniques scaffolded students' engagement in engineering design practices in all three cases. Common themes across the three cases—problem decomposition, modeling of expert practices, and facilitating students' active involvement—revealed a combination of pedagogical strategies that were interconnected and made evident through the cognitive apprenticeship model. The strategies suggest the integration of types of knowledge and engineering practices required for effective apprenticeships in similar contexts.
Embracing consumer ambivalence in the luxury shopping experience
Authors: Prestini Stefano , Sebastiani Roberta 
Published: February 2021

AbstractEmotions, feelings, attitudes, and beliefs play a pivotal role in consumer decision‐making. The literature shows that psychological concepts with opposing valence coexist in people's shopping experience. This consumer ambivalence is relevant in hedonic contexts, where cognitive and affective elements play a central role in consumer outcomes (e.g., satisfaction, loyalty, and patronage). However, there is a paucity of consumer ambivalence literature focused on hedonic retail settings; thus, this study focuses on consumer ambivalence in luxury shopping experiences. Using a multi‐method approach, the study investigated luxury shoppers' psychological concepts, both positive and negative, in order to better understand consumer ambivalence and its impact on consumer outcomes. Thus, this paper makes two main contributions. First, it revealed three types of consumer ambivalence: awe and pride; uncertainty and contentment; guilt and pleasure. Second, the combination of negative and positive cognitive and affective elements in the luxury shopping experience positively impacted consumer outcomes and led to specific shopping behaviors. On these bases, luxury brands should leverage consumer ambivalences that are embedded in and signify the overall shopping experience.
Oxa Analogues of Nexturastat A Demonstrate Improved HDAC6 Selectivity and Superior Antileukaemia Activity
Authors: Pflieger Marc , Sönnichsen Melf , Horstick‐Muche Nadine , Yang Jing , Schliehe‐Diecks Julian , Schöler Andrea , Borkhardt Arndt , Hamacher Alexandra , Kassack Matthias U. , Hansen Finn K. , Bhatia Sanil , Kurz Thomas 
Published: February 2021

AbstractThe acetylome is important for maintaining the homeostasis of cells. Abnormal changes can result in the pathogenesis of immunological or neurological diseases, and degeneration can promote the manifestation of cancer. In particular, pharmacological intervention in the acetylome with pan‐histone deacetylase (HDAC) inhibitors is clinically validated. However, these drugs exhibit an undesirable risk‐benefit profile due to severe side effects. Selective HDAC inhibitors might promote patient compliance and represent a valuable opportunity in personalised medicine. Therefore, we envisioned the development of HDAC6‐selective inhibitors. During our lead structure identification, we demonstrated that an alkoxyurea‐based connecting unit proves to be beneficial for HDAC6 selectivity and established the synthesis of alkoxyurea‐based hydroxamic acids. Herein, we report highly potent N‐alkoxyurea‐based hydroxamic acids with improved HDAC6 preference compared to nexturastat A. We further validated the biological activity of these oxa analogues of nexturastat A in a broad subset of leukaemia cell lines and demonstrated their superior anti‐proliferative properties compared to nexturastat A.
Contextual contracts for component‐oriented resource abstraction in a cloud of high performance computing services
Authors: de Carvalho Junior Francisco Heron , Al‐Alam Wagner Guimarães , de Oliveira Dantas Allberson B. 
Published: February 2021

SummaryEfforts to support high performance computing (HPC) applications' requirements in the context of cloud computing have motivated us to design HPC Shelf, a cloud computing services platform to build and deploy large‐scale parallel computing systems. We introduce Alite, the contextual contract system of HPC Shelf, to select component implementations according to requirements of the host application, target parallel computing platform characteristics (e.g., clusters and MPPs), quality of service (QoS) properties, and cost restrictions. It is evaluated through a small‐scale case study employing two complementary component‐based frameworks. The first one aims to represent components that implement linear algebra computations based on the BLAS interface. In turn, the second one aims to represent parallel computing platforms on the IaaS cloud offered by Amazon EC2 Service.
A multilevel model exploring the relationships between individual spirituality, spiritual climate, and nonviolent work behavior
Authors: Sarkar Ayatakshee , Garg Naval 
Published: February 2021

AbstractBased on Social Cognitive Theory (SCT), the present study investigated relationships between spiritual climate (environmental factor), individual spirituality (personal factor), and nonviolent work behavior. A significant association was observed between individual spirituality and nonviolent behavior. Results also concluded a significant moderation effect of spiritual climate. Transcendence, meaningful life, faith, and practicing spirituality are reported as significant predictors of nonviolent work. Two dimensions of spiritual climate, that is, authenticity and meditative work, are found to exhibit a statistically significant moderation effect. The sense of community and lokasangraha did not divulge considerable moderation. The study expands the horizon of triad relationships by suggesting indirect relationships between three factors of the SCT theory.
Green Recycling Process for Polyurethane Foams by a Chem‐Biotech Approach
Authors: Magnin Audrey , Entzmann Lisa , Bazin Alfred , Pollet Eric , Avérous Luc 
Published: February 2021

AbstractPolyurethanes (PUs) are highly resistant materials used for building insulation or automotive seats. The polyurethane end‐of‐life issue must be addressed by the development of efficient recycling techniques. Since conventional recycling processes are not suitable for thermosets, waste management of PU foam is particularly questioning. By coupling biological and chemical processes, this study aimed at developing a green recycling pathway for PU foam using enzymes for depolymerization. For instance, enzymatic degradation of a PU foam synthesized with polycaprolactone and toluene diisocyanate led to a weight loss of 25 % after 24 h of incubation. The corresponding degradation products were recovered and identified as 6‐hydroxycaproic acid and a short acid‐terminated diurethane. An organometallic‐catalyzed synthesis of second‐generation polymers from these building blocks was carried out. A polymer with a high average molar mass of 74000 (Mw) was obtained by mixing 50 % of recycled building blocks and 50 % of neat 6‐hydroxycaproic acid. A poly(ester urethane) was synthesized without the use of toxic and decried polyisocyanates. It is the first time that a study offers the vision of a recycling loop starting from PU wastes and finishing with a second‐generation polymer in a full circular approach.
Joint effects of patch edges and habitat degradation on faunal predation risk in a widespread marine foundation species
Authors: Hovel Kevin A. , Duffy J. Emmett , Stachowicz John J. , Reynolds Pamela , Boström Christoffer , Boyer Katharyn E. , Cimon Stéphanie , Cusson Mathieu , Fodrie Fredrick Joel , Gagnon Karine , Hereu Clara M. , Hori Masakazu , Jorgensen Pablo , Kruschel Claudia , Lee Kun‐Seop , Nakaoka Masahiro , O’Connor Nessa E. , Rossi Francesca , Ruesink Jennifer , Tomas Fiona , Ziegler Shelby 
Published: February 2021

AbstractHuman activities degrade and fragment coastal marine habitats, reducing their structural complexity and making habitat edges a prevalent seascape feature. Though habitat edges frequently are implicated in reduced faunal survival and biodiversity, results of experiments on edge effects have been inconsistent, calling for a mechanistic approach to the study of edges that explicitly includes indirect and interactive effects of habitat alteration at multiple scales across biogeographic gradients. We used an experimental network spanning 17 eelgrass (Zostera marina) sites across the Atlantic and Pacific oceans and the Mediterranean Sea to determine (1) if eelgrass edges consistently increase faunal predation risk, (2) whether edge effects on predation risk are altered by habitat degradation (shoot thinning), and (3) whether variation in the strength of edge effects among sites can be explained by biogeographical variability in covarying eelgrass habitat features. Contrary to expectations, at most sites, predation risk for tethered crustaceans (crabs or shrimps) was lower along patch edges than in patch interiors, regardless of the extent of habitat degradation. However, the extent to which edges reduced predation risk, compared to the patch interior, was correlated with the extent to which edges supported higher eelgrass structural complexity and prey biomass compared to patch interiors. This suggests an indirect component to edge effects in which the impact of edge proximity on predation risk is mediated by the effect of edges on other key biotic factors. Our results suggest that studies on edge effects should consider structural characteristics of patch edges, which may vary geographically, and multiple ways that humans degrade habitats.
Efficient microfluidic enrichment of nano‐/submicroparticle in viscoelastic fluid
Authors: Fan Liang‐Liang , Tian Zhuang‐Zhuang , Zhe Jiang , Zhao Liang 
Published: February 2021

AbstractThe enrichment and focusing of the nano‐/submicroparticle (e.g., 150–1000 nm microvesicle shed from the plasma membrane) in the viscoelastic fluid has great potentials in the biomedical and clinical applications such as the disease diagnosis and the prognostic test for liquid biopsy. However, due to the small size and the resulting weak hydrodynamic force, the efficient manipulation of the nano‐/submicroparticle by the passive viscoelastic microfluidic technology remains a major challenge. For instance, a typically long channel length is often required to achieve the focusing or the separation of the nano‐/submicroparticle, which makes it difficult to be integrated in small chip area. In this work, a microchannel with gradually contracted cross‐section and high aspect ratio (the ratio of the height to the average width of channel) is utilized to enhance the hydrodynamic force and change the force direction, eventually leading to the efficient enrichment of nano‐/submicroparticles (500 and 860 nm) in a short channel length (2 cm). The influence of the flow rate, the particle size, the solid concentration, and the channel geometry on the enrichment of the nano‐/submicroparticles are investigated. With simple structure, small footprint, easy operation, and good performance, the present device would be a promising platform for various lab‐chip microvesicle‐related biomedical research and disease diagnosis.