bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cuidados multiprofissionais relacionados à prevenção da pneumonia associada à ventilação mecânica
Authors: Liz Janaina Souza de , Gouvea Pollyana Bortholazzi , Acosta Adriano Da Silva , Sandri Juliana Vieira de Araújo , Paula Dagoberto Mior de , Maia Silmara Costa 
Published: January 2021

Objetivo: Conhecer a percepção da equipe multiprofissional acerca dos cuidados relacionados às medidas de prevenção a pneumonia associada à ventilação mecânica. Método: Tratou-se de um estudo descritivo, qualitativo em que participou a equipe multiprofissional atuante em UTI. Resultados: Totalizaram 20 profissionais. Verificou-se que a equipe multiprofissional conhece algumas medidas preventivas, no entanto a enfermagem percebe o fisioterapeuta como protagonista neste processo. Conclusões: A pesquisa permitiu identificar a maneira como cada membro da equipe percebe a sua atuação e a atuação do outro.Palavras-chave: Infecção Hospitalar; Enfermagem; Controle de Infecções Objective: To know the perception of the multidisciplinary team about the care related to the prevention measures against ventilator-associated pneumonia. Method: This was a descriptive and qualitative study in which the multiprofessional team working in Intensive Care Unit participated. Results: Totaled 20 professionals. It was found that the multiprofessional team knows some preventive measures, however nursing refers to the physical therapist as a protagonist in this process. It was also noticed that the nurse has a fundamental role in maintaining care before the multiprofessional team. Conclusions: The study showed that the multiprofessional team demonstrates knowledge about the preventive measures related to ventilator-associated pneumonia, as well as the professionals seek to act continuously to improve the quality of care, aiming to ensure patient safety.Descriptors: Hospital Infection; Nursing; Infection Control. Objetivo: Conocer la percepción del equipo multidisciplinario sobre la atención relacionada con las medidas de prevención contra la neumonía asociada al ventilador. Método: Este fue un estudio descriptivo y cualitativo en el que participó el equipo multiprofesional que trabajaba en la Unidad Intensiva. Resultados: totalizaron 20 profesionales. Se encontró que el equipo multiprofesional conoce algunas medidas preventivas, sin embargo, la enfermería se refiere al fisioterapeuta como protagonista en este proceso. También se notó que la enfermera tiene un papel fundamental en el mantenimiento de la atención ante el equipo multiprofesional. Conclusiones: El estudio mostró que el equipo multiprofesional demuestra conocimiento sobre las medidas preventivas relacionadas con la neumonía asociada al ventilador, así como que los profesionales buscan actuar continuamente para mejorar la calidad de la atención, con el objetivo de garantizar la seguridad del paciente.Descriptores: infección hospitalaria; Enfermería; Control de infecciones.
Enfermagem em práticas avançadas no atendimento pré-hospitalar: oportunidade de ampliação do acesso no Brasil
Authors: Malvestio Marisa Aparecida Amaro , Behringer Lilian Prates Prates Belém , Martuchi Sérgio Dias , Fonseca Marcos Aurélio da Silva , Da Silva Luciano , De Souza Eduardo Fernando , Hanszman Gilson Clementino , Bezerra Rildo 
Published: January 2021

O objetivo é analisar o cenário de implementação da EPA no atendimento pré-hospitalar (APH) como ferramenta de acesso ao cuidado de urgência no Brasil. Metodologia: Frente ao cenário das urgências, foi realizada análise da literatura relacionada a EPA e seus resultados, bem como investigação não-exaustiva sobre a participação do enfermeiro no APH em outros países, com vistas a explorar o impacto da introdução de enfermeiros na urgência pré-hospitalar no Brasil. Conclusão: A ampliação do papel dos enfermeiros no modelo brasileiro de APH pode viabilizar o alcance da cobertura 100% e incrementar a capacidade de avaliação e a realizaçãode procedimentos em tempo adequado, assegurando acesso oportuno ao cuidado. Decs: Serviços Médicos de Emergência; Prática Avançada de Enfermagem; Assistência à Saúde
Withdrawal Notice: TP53 Targetome: A Database of Novel Breast Cancer Biomarkers
Authors: Hameed Yasir , Ejaz Samina 
Published: January 2021

The article has been withdrawn from the journal “Current Drug Targets” on behalf of the editor’s request. Bentham Science apologizes to its readers for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham Science Disclaimer:
It is a condition of publishers that manuscripts submitted to this journal should not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and while submit- ting the article for publication, the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript the authors agree that the copyright of their article is transferred to the publishers, if and when the article is accepted for publication.
Forecasting of Covid-19 Cases Using Machine Learning Approach
Authors: Kumar Sachin , Veer Karan 
Published: January 2021

Aims:
The objective of this research is to predict the covid-19 cases in India based on
the machine learning approaches.

Background:
Covid-19, a respiratory disease caused by one of the coronavirus family members,
has led to a pandemic situation worldwide in 2020. This virus was detected firstly in Wuhan city of
China in December 2019. This viral disease has taken less than three months to spread across the
globe.

Objective:
In this paper, we proposed a regression model based on the Support Vector Machine
(SVM) to forecast the number of deaths, the number of recovered cases, and total confirmed cases
for the next 30 days.

Method:
For prediction, the data was collected from Github and the ministry of India's health and
family welfare from March 14, 2020, to December 3, 2020. The model has been designed in
Python 3.6 in Anaconda to forecast the forecasting value of corona trends until September 21,
2020. The proposed methodology is based on the prediction of values using SVM based regression
model with polynomial, linear, rbf kernel. The dataset has been divided into train and test datasets
with 40% and 60% test size and verified with real data. The model performance parameters were
evaluated as a mean square error, mean absolute error, and percentage accuracy.

Results and Conclusion:
The results show that the polynomial model has obtained 95% above accuracy
score, linear scored above 90%, and rbf scored above 85% in predicting cumulative death,
conformed cases, and recovered cases.
Opioid Dependency and Myocardial Infarction: A Systematic Review and Meta-Analysis
Authors: Rohani Farahnaz , Rezayat Arash A. , Zarifian Ahmadreza , Nour Mohammad G. , Vakilian Farveh , Sahebkar Amirhossein , Dadgarmoghaddam Maliheh 
Published: January 2021

Background:
Coronary artery disease is a major cause of morbidity and mortality worldwide.
A major health concern in the developing countries is opioid addiction, which has controversial
cardiovascular side effects. We aimed to investigate whether Myocardial Infarction (MI) and its risk
factors are associated with morphine dependency in the Iranian population.

Methods:
Electronic databases, including PubMed, Medline, Scopus, SID, Element, and Magiran
were searched to find published articles including the keywords morphine, coronary artery disease,
hypertension, hyperlipidemia, and diabetes mellitus.

Results:
Twelve studies involving 25,800 people were included in this systematic review and metaanalysis.
Morphine dependency was significantly associated with MI with an adjusted odds ratio
(AOR) of 2.28 (95%CI=1.26-4.11). It neither has significant associations with hypertension
(AOR=0.952; 95%CI=0.696-1.301) nor diabetes (AOR=0.895; 95%CI=0.644-1.246). Morphine dependency
also had no significant association with hyperlipidemia with a Crude Odds Ratio (COR) of
0.906 (95%CI=0.786-1.045).

Conclusion:
Morphine dependency was significantly related to MI, but its risk factors were not significantly
associated with morphine dependency. The increasing prevalence of opioid abuse in developing
countries may be a reason for the growing incidence of MI in younger ages and individuals with
no risk factors. Besides, physicians should consider the presence of impurities in morphine-based opioids
and their possible effects on health.
Withdrawal Notice: Comparison of Pharmaceutical Effect of Alemtuzumab and Natalizumab and Their Side Effects in Treatment of Various Stages of Multiple Sclerosis Patients
Authors: Mohammadi Mostafa 
Published: January 2021

This article submitted to the journal CNS & Neurological Disorders - Drug Targets; has been withdrawn upon the
request of the author due to the errors and invalid information in the article.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham Science Disclaimer:
It is a condition of publication that manuscripts submitted to this journal have not been published and will not be
simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been
published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is
strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal
right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By
submitting a manuscript the authors agree that the copyright of their article is transferred to the publishers if and
when the article is accepted for publication.
The Effect of Vitamin E on Oral Mucositis Induced by Chemotherapy in Non-Hodgkin Lymphoma Patients Receiving Chemotherapy
Authors: Hermanto Djoko Heri , Habsari Indri , Machsoos Budi Darmawan 
Published: January 2021

Chemotherapy-induced mucositis is a side effect of chemotherapy that often occurs in patients with solid tumors and lymphoma. Oral mucositis can affect nutritional status and the risk of infection, both local and systemic. Antioxidant Vitamin E is beneficial for the prevention and therapy of both oral and gastrointestinal mucositis. Aim: To determine the effect of vitamin E therapy on the incidence of oral mucositis in non-Hodgkin lymphoma (NHL) patients receiving chemotherapy. Methods: This is a single-blind experimental study in 62 NHL patients undergoing chemotherapy who meet the inclusion criteria. Patients who met the inclusion criteria were randomly divided into 2 groups, namely 31 patients (treatment group) received vitamin E 400 mg / IU per day for 7 days and 31 patients in the placebo group. The incidence and grade of oral mucositis were observed on day 7. Statistical analysis used Chi-Square and Mann Whitney test according to the data type. Results: a total of 67% NHL patients were male, most of whom were over 46 years of age and as many as 50% of patients used chemotherapy regimens RCHOP and CHOP. There was an incidence of oral mucositis in 35% in the placebo group and 12.9% in the treated group (p = 0.038). In the placebo group, there were 4.8% of patients with grade 2 and 3 oral mucositis, which was not found in the therapy group. Conclusion: Â treatment with vitamin E in NHL patients undergoing chemotherapy can prevent chemotherapy-induced oral mucositis and prevent its severity.
A Food Poisoning Outbreak in Al-Khazir U2 Camp of Internally Displaced Persons - Iraq, Summer 2017
Authors: Kadhim Kamal , Fathallah K , Al Jaafar  , Hamad A , Saadoon S , Awad Z , Lami F 
Published: January 2021

Background
Globally, about 600 million fall ill and 420,000 die every year after eating contaminated food. On June 12, 2017, Iraq CDC informed about a food poisoning outbreak among internally displaced persons (IDPs) in Al-Khazir camp, Northern Iraq after consuming “Iftar” (Ramadan breakfast) provided by an NGO. “Iftar” was composed of rice, white bean broth, chicken, yogurt, date and bread.

Objective
The objective was to describe the outbreak, identify the causative agent and recommend preventive measures.

Methods
A team of FETP residents dispatched to investigate the outbreak. The case patient was defined as any person in the camp who ate “Iftar” and developed nausea/vomiting or diarrhea or abdominal pain. A retrospective cohort study was initiated.

Results

Conclusions
The large number of ordered meals from a single restaurant led to suboptimal food preparation and storage. We recommended rigorous implementation of food handing instructions and health education of the food handlers.
Development and Evaluation of a New Serious Game for Continuing Medical Education of General Practitioners (Hygie): Double-Blinded Randomized Controlled Trial
Authors: Jaunay Louis-Baptiste , Zerr Philippe , Peguin Lino , Renouard Léandre , Ivanoff Anne-Sophie , Picard Hervé , Griffith James , Chassany Olivier , Duracinsky Martin 
Published: January 2021

Background
Continuing medical education is important but time-consuming for general practitioners (GPs). Current learning approaches are limited and lack the ability to engage some practitioners. Serious games are new learning approaches that use video games as engaging teaching material. They have significant advantages in terms of efficiency and dissemination.

Objective
The aim of this study was to create a serious game and to evaluate it in terms of effectiveness and satisfaction, comparing it with a traditional method of continuing education—article reading.

Methods
We produced a prototype video game called Hygie on the 5 most common reasons of consultation in general practice using 9 articles from independent evidence-based medicine journals (reviews from Prescrire and Minerva). We created 51 clinical cases. We then conducted a double-blinded randomized trial comparing the learning provided by a week of access to the game versus source articles. Participants were GPs involved as resident supervisors in 14 French university departments of family practice, recruited by email. Primary outcomes were (1) mean final knowledge score completed 3 to 5 weeks after the end of the intervention and (2) mean difference between knowledge pretest (before intervention) and posttest (3 to 5 weeks after intervention) scores, both scaled on 10 points. Secondary outcomes were transfer of knowledge learned to practice, satisfaction, and time spent playing.

Results
A total of 269 GPs agreed to participate in the study. Characteristics of participants were similar between learning groups. There was no difference between groups on the mean score of the final knowledge test, with scores of 4.9 (95% CI 4.6-5.2) in the Hygie group and 4.6 (95% CI 4.2-4.9) in the reading group (P=.21). There was a mean difference score between knowledge pre- and posttests, with significantly superior performance for Hygie (mean gain of 1.6 in the Hygie group and 0.9 in the reading group; P=.02), demonstrating a more efficient and persistent learning with Hygie. The rate of participants that reported to have used the knowledge they learned through the teaching material was significantly superior in the Hygie group: 77% (47/61) in the Hygie group and 53% (25/47) in the reading group; odds ratio 2.9, 95% CI 1.2-7.4. Moreover, 87% of the opinions were favorable, indicating that Hygie is of interest for updating medical knowledge. Qualitative data showed that learners enjoyed Hygie especially for its playful, interactive, and stimulating aspects.

Conclusions
We conclude that Hygie can diversify the offering for continuing education for GPs in an effective, pleasant, and evidence-based way.

Trial Registration
ClinicalTrials.gov NCT03486275; https://clinicaltrials.gov/ct2/show/NCT03486275
Smartphone-Detected Ambient Speech and Self-Reported Measures of Anxiety and Depression: Exploratory Observational Study
Authors: Di Matteo Daniel , Wang Wendy , Fotinos Kathryn , Lokuge Sachinthya , Yu Julia , Sternat Tia , Katzman Martin A , Rose Jonathan 
Published: January 2021

Background
The ability to objectively measure the severity of depression and anxiety disorders in a passive manner could have a profound impact on the way in which these disorders are diagnosed, assessed, and treated. Existing studies have demonstrated links between both depression and anxiety and the linguistic properties of words that people use to communicate. Smartphones offer the ability to passively and continuously detect spoken words to monitor and analyze the linguistic properties of speech produced by the speaker and other sources of ambient speech in their environment. The linguistic properties of automatically detected and recognized speech may be used to build objective severity measures of depression and anxiety.

Objective
The aim of this study was to determine if the linguistic properties of words passively detected from environmental audio recorded using a participant’s smartphone can be used to find correlates of symptom severity of social anxiety disorder, generalized anxiety disorder, depression, and general impairment.

Methods
An Android app was designed to collect periodic audiorecordings of participants’ environments and to detect English words using automatic speech recognition. Participants were recruited into a 2-week observational study. The app was installed on the participants’ personal smartphones to record and analyze audio. The participants also completed self-report severity measures of social anxiety disorder, generalized anxiety disorder, depression, and functional impairment. Words detected from audiorecordings were categorized, and correlations were measured between words counts in each category and the 4 self-report measures to determine if any categories could serve as correlates of social anxiety disorder, generalized anxiety disorder, depression, or general impairment.

Results
The participants were 112 adults who resided in Canada from a nonclinical population; 86 participants yielded sufficient data for analysis. Correlations between word counts in 67 word categories and each of the 4 self-report measures revealed a strong relationship between the usage rates of death-related words and depressive symptoms (r=0.41, P<.001). There were also interesting correlations between rates of word usage in the categories of reward-related words with depression (r=–0.22, P=.04) and generalized anxiety (r=–0.29, P=.007), and vision-related words with social anxiety (r=0.31, P=.003).

Conclusions
In this study, words automatically recognized from environmental audio were shown to contain a number of potential associations with severity of depression and anxiety. This work suggests that sparsely sampled audio could provide relevant insight into individuals’ mental health.
Factors Contributing to Diagnostic Discordance Between Store-and-Forward Teledermatology Consultations and In-Person Visits: Case Series
Authors: Lee Michelle S , Stavert Robert 
Published: January 2021

Background
Use of asynchronous store-and-forward (SAF) teledermatology can improve access to timely and cost-effective dermatologic care and has increased during the COVID-19 pandemic. Previous research has found high diagnostic concordance rates between SAF teledermatology and face-to-face clinical diagnosis, but to our knowledge, none have used specific cases to illustrate factors contributing to diagnostic discordance.

Objective
To identify and illustrate characteristics that may have contributed to diagnostic discordance between store-and-forward teledermatology and in-person clinical diagnosis in a series of patients.

Methods
We identified 7 cases of diagnostic discordance between teledermatology and in-person visits where the favored diagnosis of the in-person dermatologist was not included in the differential diagnosis formulated by the teledermatologist. Cases were identified from a previously published retrospective chart review of 340 SAF teledermatology consultations, which was previously performed at an academic community health care system in the greater Boston area, Massachusetts, from January 1, 2014, through December 31, 2017. Of 99 patients who completed an in-person dermatology appointment after their teledermatology consultation, 7 had diagnostic disagreement between the teledermatologist and in-person dermatologist where the diagnosis in the in-person consultation was not included in the differential diagnosis in the original teledermatology consult. These 7 cases were examined by 2 author reviewers to identify factors that may have contributed to diagnostic discordance.

Results
Factors contributing to diagnostic discordance between SAF teledermatology consultations and in-person visits included poor image quality, inadequate history or diagnostic workup, inability to evaluate textural characteristics, diagnostic uncertainty due to atypical presentations, and evolution in appearance of skin conditions over time.

Conclusions
We identified multiple factors that contributed to diagnostic discordance. Recognition and mitigation of these factors, when possible, may help to improve diagnostic accuracy and reduce the likelihood of misdiagnosis. Continuing education of referring providers and implementation of standardized guidelines for referrals may also be helpful in reducing the risk of misdiagnosis due to inherent limitations of teledermatology services.
Monitoreo de residuos de plaguicidas en ajíes dulces en mercados selectos de San José de Ocoa y Santo Domingo, República Dominicana
Authors: Vallejo Degaudenzi Alejandro , Pérez Francelyn , Marranzini Camila , Tavárez Josefina 
Published: January 2021

Los productos agrícolas dominicanos con fines de exportación se analizan constantemente en busca de residuos de plaguicidas. Algunos de estos agroalimentos presentan elevadas concentraciones de plaguicidas que sobrepasan los niveles máximos de residuos establecidos (LMR), convirtiéndose en una preocupación de seguridad alimentaria. El objetivo de este estudio fue identificar la presencia, tipos y concentraciones de 70 residuos de plaguicidas de uso común en el sector hortícola, en dos cultivares de ajíes, mediante la técnica de cromatografía de gases acoplada a espectrometría de masas (GC-MS), en mercados alimenticios seleccionados de la provincia San José de Ocoa y del Gran Santo Domingo. Desde enero del 2018 hasta junio del 2019, se recolectaron 117 muestras de ajíes dulces y estos fueron analizados utilizando la extracción de residuos múltiples QuEChERS, seguida de GC-MS. Se encontró que solo el 62 % cumplía con los LMR, siendo el clorfenapir y la cihalotrina los más frecuentemente detectados (27 y 19 muestras, respectivamente). También, se demostró la presencia de 19 variedades de plaguicidas, entre ellos dos organoclorados no permitidos: dicofol y diclorodifeniltricloroetano (DDT). Los altos niveles y la amplia variedad de residuos de pesticidas detectados en este proyecto sugieren la necesidad de promulgar regulaciones sobre el uso adecuado de pesticidas.