bluuebunny/crossref_metadata_2025_split huggingface dataset:
A 26-Year Study of Restraint Fatalities Among Children and Adolescents in the United States: A Failure of Organizational Structures and Processes
Authors: Nunno Michael A. , McCabe Lisa A. , Izzo Charles V. , Smith Elliott G. , Sellers Deborah E. , Holden Martha J. 
Published: August 2021

Abstract
Background
Physical and mechanical restraints used in treatment, care, education, and corrections programs for children are high-risk interventions primarily due to their adverse physical, emotional, and fatal consequences.

Objective
This study explores the conditions and circumstances of restraint-related fatalities in the United States by asking (1) Who are the children that died due to physical restraint? and (2) How did they die?

Method
The study employs internet search systems to discover and compile information about restraint-related fatalities of children and youth up to 18 years of age from reputable journalism sources, advocacy groups, activists, and governmental and non-governmental agencies. The child cohort from a published study of restraint fatalities in the United States from 1993 to 2003 is combined with restraint fatalities from 2004 to 2018. This study’s scope has expanded to include restraint deaths in community schools, as well as undiscovered restraint deaths from 1993 to 2003 not in the 2006 study.

Results
Seventy-nine restraint-related fatalities occurred over the 26-year period from across a spectrum of children’s out-of-home child welfare, corrections, mental health and disability services. The research provides a data snapshot and examples of how fatalities unfold and their consequences for staff and agencies. Practice recommendations are offered to increase safety and transparency.

Conclusions
The study postulates that restraint fatalities result from a confluence of medical, psychological, and organizational causes; such as cultures prioritizing control, ignoring risk, using dangerous techniques, as well as agencies that lack structures, processes, procedures, and resources to promote learning and to ensure physical and psychological safety.
Mothers’ and Children’s Mental Health During the COVID-19 Pandemic Lockdown: The Mediating Role of Parenting Stress
Authors: Babore Alessandra , Trumello Carmen , Lombardi Lucia , Candelori Carla , Chirumbolo Antonio , Cattelino Elena , Baiocco Roberto , Bramanti Sonia Monique , Viceconti Maria Luisa , Pignataro Silvia , Morelli Mara 
Published: August 2021

AbstractThe present study, carried out during the first peak of the COVID-19 outbreak in Italy, aimed at investigating the mental health of mothers and children during the nationwide lockdown. More specifically, the study investigated children’s depression and mothers’ individual distress and parenting stress, in comparison with normative samples. The mediating effect of mothers’ parenting stress on the relationship between mothers’ individual distress and children’s depression was also explored. Finally, the study analyzed whether children’s biological sex and age moderated the structural paths of the proposed model. A sample of 206 Italian mothers and their children completed an online survey. Mothers were administered self-report questionnaires investigating individual distress and parenting stress; children completed a standardized measure of depression. Mothers’ individual distress and parenting stress and children’s depression were higher than those recorded for the normative samples. Mothers’ parenting stress was found to mediate the association between mothers’ individual distress and children’s depression. With respect to children, neither biological sex nor age emerged as significant moderators of this association, highlighting that the proposed model was robust and invariant. During the current and future pandemics, public health services should support parents—and particularly mothers—in reducing individual distress and parenting stress, as these are associated with children’s depression.
The Impact of Career Concerns and Cognitive Dissonance on Bureaucrats’ Use of Benefit-Cost Analysis
Authors: Hammes Johanna Jussila 
Published: August 2021

AbstractPrevious research shows that Benefit-Cost Analysis (BCA) is seldom done in Sweden, and that the results e.g., in Norway and the Netherlands do not influence the ultimate policy choice. We explain why bureaucrats may choose (not) to do a BCA with cognitive- and search costs coupled with career concerns. Given the initial policy chosen by an agenda setter, bureaucrats who stay working at an agency have policy preferences close to the initial policy; those with reservation wages above a threshold quit and therefore do not influence policy. The bureaucrats’ preferences converge to the initial policy level over time. A BCA reveals the inefficiency of the initial policy and the bureaucrats consequently have no incentive to do one, except when the policy is restricted by a binding governmental budget constraint.
Unfettering discussions about social justice: the role of conversational prompts in discussions about mathematics education for Indigenous students
Authors: Meaney Tamsin , Fyhn A. B. , Graham S. R. W. 
Published: August 2021

AbstractTo increase possibilities for listening respectfully to Indigenous educators, there is a need to identify conversational prompts which are used to raise alternative views of social justice about mathematics education for Indigenous students. Using Nancy Fraser’s description of abnormal social justice, an analysis was made of transcripts from round table sessions, at an Indigenous mathematics education conference. This analysis identified a number of conversational prompts that enabled shifts from normal to abnormal discussions about social justice. Normal discussions exhibited assumptions in which mathematics was valued as a Western domain of knowledge; cultural examples could be used as vehicles to teach mathematics; and decisions about education for Indigenous students should be made by external authorities. In abnormal discussions, these assumptions were queried and alternative possibilities arose. The conversational prompts, which initiated this querying, occurred in a number of ways, including the telling of stories and the asking of questions that either directly or indirectly challenged normal justice discourses about Indigenous students’ learning of mathematics. Identifying conversational prompts can assist non-Indigenous mathematics educators, who wish to be allies, to challenge their own and others’ assumptions about normal social justice issues related to mathematics education for Indigenous students.
Spinal Cord Injury Increases Pro-inflammatory Cytokine Expression in Kidney at Acute and Sub-chronic Stages
Authors: Parvin Shangrila , Williams Clintoria R. , Jarrett Simone A. , Garraway Sandra M. 
Published: August 2021

Abstract—
Accumulating evidence supports that spinal cord injury (SCI) produces robust inflammatory plasticity. We previously showed that the pro-inflammatory cytokine tumor necrosis factor (TNF)α is increased in the spinal cord after SCI. SCI also induces a systemic inflammatory response that can impact peripheral organ functions. The kidney plays an important role in maintaining cardiovascular health. However, SCI-induced inflammatory response in the kidney and the subsequent effect on renal function have not been well characterized. This study investigated the impact of high and low thoracic (T) SCI on C-fos, TNFα, interleukin (IL)-1β, and IL-6 expression in the kidney at acute and sub-chronic timepoints. Adult C57BL/6 mice received a moderate contusion SCI or sham procedures at T4 or T10. Uninjured mice served as naïve controls. mRNA levels of the proinflammatory cytokines IL-1β, IL-6, TNFα, and C-fos, and TNFα and C-fos protein expression were assessed in the kidney and spinal cord 1 day and 14 days post-injury. The mRNA levels of all targets were robustly increased in the kidney and spinal cord, 1 day after both injuries. Whereas IL-6 and TNFα remained elevated in the spinal cord at 14 days after SCI, C-fos, IL-6, and TNFα levels were sustained in the kidney only after T10 SCI. TNFα protein was significantly upregulated in the kidney 1 day after both T4 and T10 SCI. Overall, these results clearly demonstrate that SCI induces robust systemic inflammation that extends to the kidney. Hence, the presence of renal inflammation can substantially impact renal pathophysiology and function after SCI.
Interocular biometric parameters comparison measured with swept-source technology
Authors: Albarrán-Diego César , Poyales Francisco , López-Artero Esther , Garzón Nuria , García-Montero María 
Published: August 2021

Abstract
Purpose
In the event that any ocular parameter involved in the calculation of intraocular lens power could not be properly measured in one eye, it is important to know whether clinically relevant differences between both eyes can be expected. The aim of this work is to evaluate the symmetry of interocular biometric parameters.

Methods
This was a prospective, cross-sectional study involving 4090 subjects. Patients underwent consecutive swept-source optical biometry performed with an IOLMaster 700 (Carl Zeiss Meditec AG, Jena, Germany). The biometric parameters that were evaluated were: axial length (AL), mean anterior curvature (Rm), anterior chamber depth (ACD), crystalline lens thickness (LT), central corneal thickness (CCT) and white-to-white (WTW). The Chang–Waring chord distance (CWC-D) and the Chang–Waring chord angle (CWC-A) were also evaluated.

Results
There is an excellent correlation between both eyes for almost all the biometric parameters under study, with the exception of the CWC. Agreement for AL was better for eyes shorter than 24 mm. The linearity of the OD-vs-OS relationship can be correctly assumed for all parameters (Cusum test: p > 0.05 in all cases).

Conclusion
There are no clinically significant interocular differences for the biometric parameters under study, although for all of them, except the LT, statistically significant differences did arise. In the case of AL, moderate differences can be expected in eyes larger than 24 mm.
A demographic and ecological study of an Italian population of Polyommatus ripartii: the ESU Polyommatus exuberans
Authors: Parile Enrico , Piccini Irene , Bonelli Simona 
Published: August 2021

AbstractPolyommatus exuberansis an evolutionarily significant unit (ESU) of the lycaenid butterflyPolyommatus ripartii. This ESU is known to survive at only two sites in the Susa Valley (NW Italy). Lack of correct management, reforestation and frequent wildfires severely threaten this ESU (listed as endangered species in the most recent IUCN Italian Red List). Although the taxonomic rank of this taxon is still debated, current threats could cause extinction of its two remaining populations before its taxonomic rank and its ecology are clarified. We collected data for the first time on this population at the small site of Mompantero (ab. 10 ha). We used butterfly GPS-positioning and the mark-release-recapture (MRR)-method to estimate its population size (269 individuals), sex-ratio (1.36 M/F), lifespan (4.76 days), density (47/ha) and mobility (median 153 and 33 m for males and females, respectively). Both sexes are equally catchable. Catchability increases around midday and decreases during overcast weather. While the size and density of this small population are comparable to those of other endemicPolyommatusspecies (such asP. humedasaeandP. gennargenti), scarce mobility makes its populations isolated and even more seriously threatened.Implications for insect conservationWe suggest that implementing an active management plan, including mowing before July and/or in autumn, and supporting ant diversity, is of immediate importance. Management should be extended to road verges, where the larval host plant (Onobrychissp.) is abundant, and would thus also serve as corridors to favour dispersion between sites. Our research is the first study to investigate this taxon, thus shedding some light on the ecological and biological aspects that are crucial for long-term survival.
Repair of long bone defects of large size using a tissue-engineered periosteum in a rabbit model
Authors: Zhao Lin , Zhao Junli , Tuo Zhenhe , Ren Guangtie 
Published: August 2021

AbstractTissue engineering is a promising approach for bone regeneration. In this study, we aimed to investigate whether tissue engineered periosteum (TEP), which was fabricated by combining osteogenically-induced mesenchymal stem cells (MSCs) with porcine small intestinal submucosa (SIS), could restore long bone defects of large size in rabbits. Twenty-four adult New Zealand white rabbits (NZWRs) were used in the experiments. Long bone defects of large size (30 mm-50 mm; average, 40 mm) were established on both sides of NZWRs’ radii. The defects were treated with TEP (Group A), allogeneic deproteinized bone (DPB, Group B), TEP combined with DPB (Group C), and pure SIS (Group D). The healing outcome was evaluated by radiography and histological examination at 4, 8, and 12 weeks post-treatment. The radiographical findings showed that bone defects of large size were all repaired in Groups A, B and C within 12 weeks, whereas Group D (pure SIS group) failed to result in defect healing at 4, 8, and 12 weeks. Although there was some new bone regeneration connecting the allografts and bone ends, as observed under radiographical and histological observations, bone defects of large sizes were restored primarily by structurally allografted DPB within 12 weeks. The TEP groups (Groups A and C) showed partial or total bone regeneration upon histological inspection. Based on 12-week histological examinations, significantly more bone was formed in Group A than Group C (P < 0.05), and both groups formed significantly more bone than in Groups B and D. The results indicated that long bone defects of a large size could be restored by TEP or TEP combined with the DPB scaffold, and such materials provide an alternative approach to resolving pathological bone defects in clinical settings.
Minimum-uncertainty coherent states of the hyperbolic and trigonometric Rosen–Morse oscillators
Authors: Molski Marcin 
Published: August 2021

AbstractA mixed supersymmetric-algebraic approach is employed to generate the minimum uncertainty coherent states of the hyperbolic and trigonometric Rosen–Morse oscillators. The method proposed produces the superpotentials, ground state eigenfunctions and associated eigenvalues as well as the Schrödinger equation in the factorized form amenable to direct treatment in the algebraic or supersymmetric scheme. In the standard approach the superpotentials are calculated by solution of the Riccati equation for the given form of potential energy function or by differentiation of the ground state eigenfunction. The procedure applied is general and permits derivation the exact analytical solutions and coherent states for the most important model oscillators employed in molecular quantum chemistry, coherent spectroscopy (femtochemistry) and coherent nonlinear optics.
The effect of natural disasters on FDI attraction: a sector-based analysis over time and space
Authors: Neise Thomas , Sohns Franziska , Breul Moritz , Revilla Diez Javier 
Published: August 2021

AbstractExtensive research has addressed the question of why some countries are able to attract a large amount of foreign direct investment (FDI), while others are not. Until now, this research mostly neglected natural disasters as a business risk. In the realm of natural disaster research, some studies have investigated the effect of natural disasters on FDI inflow. However, this research remains overly simplistic and conceals the complexities of the underlying relationship. As such, this article aims to provide a more deciphered perspective by considering variations across economic sectors and the dynamic effect of natural disasters. We apply hybrid panel regressions to a dataset of 181 countries over a period of 13 years across four different economic sectors. The analysis shows that the effect of natural disasters on FDI inflow varies among economic sectors. From a longitudinal perspective, the study finds a positive relationship between exposure to natural disasters and the inflow of FDI within countries 3 and 5 years after an event. Overall, the findings highlight the complex nature of the relationship between natural disasters and FDI and warn against using too simplistic approaches.
Identifying material parameters in crystal plasticity by Bayesian optimization
Authors: Kuhn Jannick , Spitz Jonathan , Sonnweber-Ribic Petra , Schneider Matti , Böhlke Thomas 
Published: August 2021

AbstractIn this work, we advocate using Bayesian techniques for inversely identifying material parameters for multiscale crystal plasticity models. Multiscale approaches for modeling polycrystalline materials may significantly reduce the effort necessary for characterizing such material models experimentally, in particular when a large number of cycles is considered, as typical for fatigue applications. Even when appropriate microstructures and microscopic material models are identified, calibrating the individual parameters of the model to some experimental data is necessary for industrial use, and the task is formidable as even a single simulation run is time consuming (although less expensive than a corresponding experiment). For solving this problem, we investigate Gaussian process based Bayesian optimization, which iteratively builds up and improves a surrogate model of the objective function, at the same time accounting for uncertainties encountered during the optimization process. We describe the approach in detail, calibrating the material parameters of a high-strength steel as an application. We demonstrate that the proposed method improves upon comparable approaches based on an evolutionary algorithm and performing derivative-free methods.
Flow and the dynamics of conscious thought
Authors: Shepherd Joshua 
Published: August 2021

AbstractThe flow construct has been influential within positive psychology, sport psychology, the science of consciousness, the philosophy of agency, and popular culture. In spite of its longstanding influence, it remains unclear [a] how the constituents of the flow state ‘hang together’—how they relate to each other causally and functionally—[b] in what sense flow is an ‘optimal experience,’ and [c] how best to describe the unique phenomenology of the flow state. As a result, difficulties persist for a clear understanding of the flow state’s structure and function. After explicating the standard view of the flow construct (section one), I articulate several basic questions regarding its nature and functional roles (section two), and I argue that these questions are best answered by integrating flow within broader streams of research on the dynamics of thought, on cognitive control resource allocation, and on creative thought (sections three and four).
Contrasting ability of deep and shallow rooting rice genotypes to grow through plough pans containing simulated biopores and cracks
Authors: Islam M.D. Dhin , Price Adam H. , Hallett Paul D. 
Published: August 2021

Abstract
Aims
Cracks and biopores in compacted soil such as plough pans could aid deep rooting, mitigating constraints to seasonal upland use of paddy fields for rice production. This research investigated how soil macropores through a simulated plough pan affects root growth of contrasting deep and shallow rooting rice genotypes.

Methods
Deep rooting Black Gora and shallow rooting IR64 rice varieties were grown in packed cores of unsaturated soil in a controlled greenhouse. Simulated biopores and cracks (macropores) were inserted through the plough pan to form treatments with no macropores, biopores, cracks, and combined cracks and biopores. Different root parameters such as root length density (RLD), root volume, root diameter, number of root tips and branches were measured. The number of roots was calculated manually, including the number of roots growing through macropores in the plough pan layer.

Results
Plough pans with macropores had 25–32% more roots than with no macropores. RLD was 55% greater in the plough pan layer if cracks were present compared to biopores. Conversely, RLD was 26% less in subsoil if the plough pan had cracks compared to biopores. Different root parameters were greatly influenced by the presence of macropores in the plough pan, and deep-rooted Black Gora produced 81% greater RLD, 30% more root numbers and 103% more branching than the shallow rooted rice genotype IR64 within the plough pan layer.

Conclusions
Macropores greatly improve rice root growth through plough pans for a deep rooting but not a shallow rooting rice variety. Whereas cracks produce a greater number of roots in the plough pan, biopores result in greater root branching and root numbers deeper in subsoil.
Missing data strategies for the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) in Alliance A091105 and COMET-2
Authors: Mazza Gina L. , Petersen Molly M. , Ginos Brenda , Langlais Blake T. , Heon Narre , Gounder Mrinal M. , Mahoney Michelle R. , Zoroufy Alexander J. , Schwartz Gary K. , Rogak Lauren J. , Thanarajasingam Gita , Basch Ethan , Dueck Amylou C. 
Published: August 2021

Abstract
Purpose
Missing scores complicate analysis of the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) because patients with and without missing scores may systematically differ. We focus on optimal analysis methods for incomplete PRO-CTCAE items, with application to two randomized, double-blind, placebo-controlled, phase III trials.

Methods
In Alliance A091105 and COMET-2, patients completed PRO-CTCAE items before randomization and several times post-randomization (N = 64 and 107, respectively). For each trial, we conducted between-arm comparisons on the PRO-CTCAE via complete-case two-sample t-tests, mixed modeling with contrast, and multiple imputation followed by two-sample t-tests. Because interest lies in whether CTCAE grades can inform missing PRO-CTCAE scores, we performed multiple imputation with and without CTCAE grades as auxiliary variables to assess the added benefit of including them in the imputation model relative to only including PRO-CTCAE scores across all cycles.

Results
PRO-CTCAE completion rates ranged from 100.0 to 71.4% and 100.0 to 77.1% across time in A091105 and COMET-2, respectively. In both trials, mixed modeling and multiple imputation provided the most similar estimates of the average treatment effects. Including CTCAE grades in the imputation model did not consistently narrow confidence intervals of the average treatment effects because correlations for the same PRO-CTCAE item between different cycles were generally stronger than correlations between each PRO-CTCAE item and its corresponding CTCAE grade at the same cycle.

Conclusion
For between-arm comparisons, mixed modeling and multiple imputation are informative techniques for handling missing PRO-CTCAE scores. CTCAE grades do not provide added benefit for informing missing PRO-CTCAE scores. ClinicalTrials.gov Identifiers: NCT02066181 (Alliance A091105); NCT01522443 (COMET-2).