bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrated reporting in China: a mission approach
Authors: Zhao Xinyu , Omran Mohamed , How Shi-Min 
Published: December 2024

PurposeDrawing on a mission approach, this study investigates the application of integrated reporting (IR). It also explores its role in shaping organisations' internal processes in Chinese state-owned enterprises (SOEs) and the China General Nuclear Power Corporation (CGN).Design/methodology/approachWe employed a case study method and collected data by conducting semi-structured interviews with CGN managers and analysing their reports and appropriate documents.FindingsOur findings reveal that the CGN is motivated by its mission and vision to adopt IR rather than by other common motivations, such as legitimacy, strategy and stakeholder pressure. IR practice contributes to implementing its mission and vision through direct and indirect methods, covering the changes in design archetypes and subsystems that meet the nature of reorientation changes that belong to first-order transition.Research limitations/implicationsThis study extends empirical evidence of IR at the firm level in China and provides in-depth insights into how IR is implemented in Chinese SOEs. Our findings may be helpful for policymakers to review and develop policies. For instance, the government might consider integrating IR frameworks into current reporting and mandate listed companies to adopt IR. However, our data are from one company, the only Mainland Chinese Company recognised by the IIRC database.Originality/valueThis study provides an innovative approach to analysing IR and offers managers insight into how IR practice benefits the mission’s implications.
Attention to Israel’s war on Gaza and stock price behavior: evidence from the Tel Aviv market
Authors: Ahmed Walid M.A. , Sleem Mohamed A.E. 
Published: December 2024

PurposePublic interest in global events has become a robust driver of investor behavior and market dynamics. This paper assesses the potential influence of attention to the 2023 Israel–Palestine war on the Tel Aviv stock market performance. Our investigation includes both the aggregate market and major sectors.Design/methodology/approachLeveraging the Google Trends service, we track search interest for a rich list of 20 terms closely linked to the ongoing conflict. Subsequently, we employ principal component analysis to construct a proxy indicator for war-related attention. To examine the potential influence of this attention on stock price returns and volatility, we adopt an EGARCH-X(p, q) framework, incorporating proxy factors to mitigate potential model under-specification issues.FindingsThe results suggest that increased attention to Israel’s invasion of Gaza is associated with negative returns and heightened volatility across most sectors. Additionally, the finance and technology sectors appear to be the most vulnerable, whereas the industrials and real estate sectors show comparatively lower levels of impact.Practical implicationsGiven the observed negative effects of public attention to geopolitical conflicts on stock price dynamics, investors should consider incorporating geopolitical risk assessments into their investment strategies. Understanding how the Israel–Palestine conflict affects market behavior can help investors and fund managers make more informed decisions, including diversifying their asset portfolios to reduce risk or adjusting their positions in sectors most susceptible to such events.Originality/valueTo our best knowledge, this paper presents the first attempt to leverage the ongoing Israel–Palestine war as a compelling example to assess how public awareness of, and reactions to, interstate conflicts impinge on financial market returns and volatility.
Knowledge-oriented leadership and business performance: the mediating role of intellectual capital and sustainable competitive advantage in the knowledge-intensive service industry
Authors: Ghlichlee Behrooz , Bayat Fatemeh , Hatami Amir 
Published: December 2024

Purpose The purpose of this study is to examine the relationship between knowledge-oriented leadership (KOL) and business performance (BP) in a knowledge-intensive industry and further investigate, heretofore neglected, a mediating effect of intellectual capital and sustainable competitive advantage in the relationship between KOL and BP.Design/methodology/approach A quantitative approach was adopted to conduct the present study. Data were collected from the full-service branches of private banks in Tehran, Iran. A confirmatory factor analysis was conducted to ascertain the validity and reliability of the observed items, and a structural equation model was employed for testing the proposed hypotheses.Findings The findings revealed that both intellectual capital and sustainable competitive advantage fully mediate the influence of KOL on branch performance.Research limitations/implications The study was conducted in the banking sector in Iran. Therefore, our conclusions may not be applicable to other countries. Future studies should be carried out with samples from other contexts. Moreover, as the study was cross-sectional, the causal relationships could not be inferred directly.Practical implications In this study, we found that knowledge-oriented leaders should increase their investment in intellectual capital to gain competitive advantage and improve branch performance.Originality/value This study contributes to advanced research on KOL by trying to explain how intellectual capital and sustainable competitive advantage can influence the relationship between KOL and BP in a knowledge-intensive service industry.
Reflections and recommendations on respectful co-production of social marketing research with Indigenous people
Authors: Cateriano-Arévalo Erik , Soria Gonzáles (Pene Beso) Jorge , Soria Gonzales (Xawan Nita) Richard , Paiva Pinedo (Sanken Bea) Néstor , Gordon Ross , Pesantes Maria Amalia , Schuster Lisa 
Published: December 2024

Purpose
Respectful co-production is one of the principles of ethical Indigenous research. However, this participatory approach has yet to be thoroughly discussed in social marketing. This study aims to provide reflections and recommendations for respectful co-production of research with Indigenous people in social marketing.

Design/methodology/approach
This study draws upon case study reflections and lessons learned from a research program respectfully co-produced with members of the Shipibo-Konibo Indigenous group of the Peruvian Amazon called the Comando Matico. The authors focus on the challenges and strategies for respectful co-production during different stages of the research process, including consultation, fieldwork and co-authoring articles. The authors foreground how their Comando Matico co researchers infused the research process with Shipibo knowledge.

Findings
The authors reflect on three recommendations concerning 1) respectful co-production, 2) power dynamics and 3) facilitating co-authorship. Social marketers interested in respectful co production of research with Indigenous people may need to adopt a flexible and practical approach that considers the characteristics of the context and Indigenous co-researchers.

Originality/value
This study contributes to the discussion about the importance of respectful co-production of research with Indigenous people to ensure it accounts for their needs and wants.
Leadership competencies in public health: implications for nursing leadership – a scoping review
Authors: Rojko Lucija , Kvas Andreja , Stare Janez 
Published: December 2024

Purpose
Effective leadership in public health organisations is essential for achieving positive outcomes and ensuring the quality of healthcare services. This review aimed to identify the competencies that nurse leaders of organisations working in the field of public health need to perform their tasks effectively.

Design/methodology/approach
A descriptive method with a scoping review was used, searching the PubMed, ScienceDirect, and CINAHL databases. A total of 16 references were suitable for the final analysis. A summative literature analysis was conducted, identifying leadership competencies (N = 69) across various sources. The identified competencies were analysed by qualitative approach.

Findings
Competencies were categorised in 11 groups: Identifying Needs and Continuous Improvement; Strategic Planning in Line with Vision and Mission; Ensuring Professional Development; Maintaining Motivation; Delegating and Managing Tasks; Communication Skills; Building and Maintaining Relationships with Decision Makers; Problem Solving and Conflict Management; Tracking Professional Trends and Using Accurate Information; Resource Management and Human Resource Management; Organising Work.

Originality/value
The 11 groups of leadership competencies for nurses in public health organisations provide a content direction for educational activities aimed at nurse leaders and summarise the most important competencies required for effective leadership in public health organisations. Competent leadership is vital for the success and effectiveness of public health organisations in delivering quality healthcare services and addressing the evolving healthcare needs. Further research within specific field in public health is recommended to identify additional, field-specific competencies essential for effective leadership in diverse organisational settings.
A comparative analysis of deterministic and probabilistic approaches for estimating seepage flow in earth dams using a hybrid finite element method
Authors: Kheiry Milad , Kalateh Farhoud 
Published: December 2024

Purpose
Computing seepage discharge in earth dams involves inherent complexities and challenges that require the use of probabilistic algorithms to accurately capture their uncertain characteristics and identify optimal solutions. This study aims to investigate the impact of uncertainty in seepage flow estimation using a novel hybrid approach, combining the analysis of Laplacian equations with the probabilistic finite element method (PFEM) and a metaheuristic algorithm.

Design/methodology/approach
To achieve this purpose, a finite element-based FORTRAN program was developed to model the problem using the Galerkin finite element method, which was validated using laboratory findings. Subsequently, Monte Carlo loops were incorporated into each model, consisting of 2000 iterations and the probability distribution function and cumulative distribution function were computed for each sub-model. A total of 138 earth dams were analysed to investigate the influence of different characteristics on seepage, including variations in dam geometry, soil permeability and water levels (both downstream and upstream). Effective seepage flow (ESF), was introduced in both deterministic and probabilistic models.

Findings
The findings indicated that the downstream slope has a more significant impact on ESF than the upstream slope, with a difference of 1.29%. Additionally, the ratio of dam height to bottom width (H/B) directly affects the ESF, resulting in a 20% increase in ESF for every 16% increase in H/B.

Originality/value
This study introduces a novel hybrid approach for estimating seepage flow in earth dams by integrating the Unlike traditional deterministic models, which often overlook the inherent .PFEM with a metaheuristic algorithman advanced uncertainties in seepage characteristics, this research effectively captures these uncertainties throughprobabilistic framework.
High Salt Exacerbates Myocardial Dysfunction In Vitro and In Vivo by Promoting SIRT1/Nrf2‐Mediated Ferroptosis
Authors: Guanji Wu , Fuqiang Liu , Fei You , Zhang Tao , Xiaolin Chen 
Published: December 2024

ABSTRACTMyocardial dysfunction is a crucial determinant of the development of heart failure in salt‐sensitive hypertension. Ferroptosis, a programmed iron‐dependent cell death, has been increasingly recognised as an important contributor to the pathophysiology of various cardiovascular diseases. This study aims to investigate the role and underlying mechanism of ferroptosis in high‐salt (HS)‐induced myocardial damage. Our results reveal that HS stimulation inhibited cell proliferation and promoted apoptosis in cardiomyocyte HL‐1 cells in a dose‐dependent manner. Ferroptotic features were observed in HS‐induced HL‐1 cells, including ferric iron accumulation, decreased glutathione levels, increased oxidative stress levels, upregulation of ferroptosis marker proteins PTGS2, 4HNE and FTH1 and downregulation of GPX4, all of which were reversed by treatment with the ferroptosis suppressor Fer‐1. Furthermore, the administration of Fer‐1 ameliorated HS‐induced ferroptosis and myocardial damage in salt‐sensitive Dahl SS rats. Additionally, we found that a HS diet suppressed the SIRT1/Nrf2 signalling pathway activation in our in vivo experiments. Activation of SIRT1/Nrf2 signalling by SIRT1 overexpression significantly attenuated ferroptosis in HS‐induced HL‐1 cells. In conclusion, our findings demonstrate that HS levels induce myocardial injury by promoting ferroptosis via the deactivation of the SIRT1/Nrf2 signalling pathway, highlighting the potential for therapeutic targeting of ferroptosis for hypertension‐related cardiovascular disorders.
Characterization of yellowfin tuna (Thunnus albacares) skin gelatin extracted by bromelain hydrolysis and ultrasound pre‐treatment
Authors: Haryati Dian , Ningrum Andriati , Witasari Lucia Dhiantika 
Published: December 2024

AbstractYellowfin tuna skin waste is a potential collagen source for gelatin through hydrolysis. Enzymatic hydrolysis is eco‐friendly but expensive, necessitating efficiency improvements. Ultrasound pre‐treatment enhances efficiency via cavitation effects. This study evaluated the effects of ultrasound amplitude, pre‐treatment duration, enzyme concentration, and hydrolysis duration on yield; determined optimal conditions for ultrasound‐assisted enzymatic extraction on yield, viscosity, and gel strength; and assessed the gelatin's physicochemical and functional properties. This research consists of three stages, factor screening using one variable at a time, optimization using response surface methodology with Box‐Behnken design, and gelatin characterization. The study included three replicates. Screening identified factor ranges for optimization: 5–25 min pre‐treatment, 1%–3% enzyme concentration, and 1–5 h hydrolysis. Optimization involved 15 experimental runs, focusing on yield, viscosity, and gel strength. Optimal conditions were 25 min pre‐treatment, 1% enzyme concentration, and 2.17 h hydrolysis, yielding 64.08%, 9.29 mPa·s viscosity, and 166.28 bloom gel strength. The optimized gelatin showed emulsifying properties with EAI 50.5 m2/g and ESI 23.80 min, water‐oil holding capacities of 192% and 406%, respectively, antioxidant activity of 60.16%, and molecular weight range of 17–160 kDa. The amino acid composition was mainly glycine (29.26%) and proline (18.26%), with 76.95% digestibility. This innovative, environmentally friendly extraction method improved gelatin extraction efficiency from yellowfin tuna skin, supporting a sustainable industry.
Extraction, characterization, and hemostatic effect of collagen from the scales of Megalonibea fusca
Authors: Li Guangfeng , Guo Tengfei , Chen Huaizhong , Huang Zhihao , Chen Qunjie , Wu Chaoxi , Wang Yifei 
Published: December 2024

AbstractMarine collagen is gaining more attraction than terrestrial collagen because it is free of zoonotic disease and religious constrain. In this study, we aimed to investigate and compare the physicochemical properties and functional characteristics of acid‐soluble collagen (ASC‐MF) and pepsin‐soluble collagen (PSC‐MF) extracted from scales of Megalonibea fusca. ASC‐MF and PSC‐MF were evaluated in terms of yield, collagen type, amino acid composition, thermal stability, microstructure, cytotoxicity, and other physicochemical parameters. ASC‐MF and PSC‐MF depicted 1.72 ± 0.2% and 11.72 ± 0.3% of dry weight yields, respectively, and were identified as type I collagen with an intact triple‐helical structure by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS‐PAGE), spectroscopic analysis, and electron microscopy. Additionally, compared with many temperate and tropical species, ASC‐MF and PSC‐MF showed higher thermal stability, with the maximum transition temperature (Tmax) of 53.50°C (ASC‐MF) and 43.16°C (PSC‐MF). CCK‐8 assay showed that ASC‐MF and PSC‐MF have no cytotoxicity in vitro. The determination of blood clotting index values showed that both ASC‐MF and PSC‐MF had good hemostatic ability. In summary, these findings show that PSC‐MF isolated from the scales of M. fusca may be a feasible alternative to terrestrial collagen sources in food and biomedical applications.
Effects of brown seaweed oligosaccharides on obesity and constipation managements
Authors: Gao Jingyu , Wu Fan , Yan Mingzhu , Wang Xuejiang , Chi Yan , Zhang Yu , Peng Yu , Li Mo , Ni Yuanying , Wen Xin 
Published: December 2024

AbstractBrown seaweed oligosaccharides (BSO) have demonstrated potential as nutraceuticals with cholesterol‐lowering, anti‐obesity, and anti‐constipation properties. In this study, we initially examined how BSO impact body weight, blood lipid levels, and adipose tissue in a rat model of obesity induced by a high‐fat diet. Our findings revealed that BSO administration significantly attenuated body weight gain, ameliorated dyslipidemia, and reduced visceral adiposity. Additionally, we evaluated the prophylactic efficacy of BSO in a loperamide hydrochloride‐induced constipation mouse model by assessing defecation parameters and gastrointestinal motility. Our results indicated that BSO intervention significantly increased fecal pallet output and fecal water content, as well as improved intestinal transit. In conclusion, this study lays the foundation for a deeper understanding of how BSO may influence obesity and constipation, offering novel insights into its potential safe and efficacious clinical applications.
Association of Biomarkers Such as CA, TP, TES and ALP With Osteoarthritis Risk: A Mendelian Randomized Study
Authors: Chen Anqi , Cai Qiang 
Published: December 2024

ABSTRACTObjectiveOsteoarthritis is a common joint disease caused by a variety of risk factors, and it has been found that many biochemical markers are abnormal in peripheral blood and urine of patients with OA. The aim of this study was to elucidate the causal relationship between biomarkers associated with these processes and OA using Mendelian randomization (MR) analysis.MethodThe inverse variance weighted (IVW) approach to MR was primarily used to explore causal associations between exposures and outcomes using publicly available genetic variants from large genome‐wide association studies (GWAS). That is, single nucleotide polymorphisms (SNPs) associated with 35 human blood and urine markers (363 228 healthy participants) were used as exposure, and osteoarthritis, hip osteoarthritis, and knee osteoarthritis were used as outcome variables, with the aim of exploring the causal relationship between 35 human blood and urine markers and osteoarthritis. MR‐Egger, weighted median (WM), and simple and weighted models were used as complementary methods to IVW to assess the reliability of causality. Steiger's test was used to confirm whether the causal relationship between exposure and outcome was biased by reverse causality. Sensitivity analyses used Cochran's Q statistic and funnel plots to detect heterogeneity, and the MR‐Egger intercept test and leave‐one‐out to assess horizontal multidimensionality.ResultsOur MR analysis study identified the protective effects of CA, TP, ALB, SHBG, and VITD on OA and the pathogenic effects of TES, ALP, GGT, CRP, and CHOL on OA. It suggests that the above 10 hematological and urinary markers have the potential to be important indicators for the clinical diagnosis of OA as well as for the assessment of therapeutic efficacy and disease progression.ConclusionThis MR analysis reinforces the importance of biomarkers in the diagnosis and prediction of OA. Future studies should further investigate the mechanisms of these biomarkers and their potential as therapeutic targets for OA.
Single‐Stage Reconstruction of Large Scalp Surgical Defects With Exposed Bone Using Matriderm Flex and Full‐Thickness Skin Grafts, a Case Report
Authors: Gil‐Pallares Pedro , Almenara‐Blasco Manuel , Navarro‐Bielsa Alba , Gilaberte Yolanda 
Published: December 2024

ABSTRACTThe reconstruction of full‐thickness scalp defects with exposed bone can be challenging. A single‐stage reconstruction could be the preferred option for patients with multiple comorbidities. We propose using a dermal regeneration template (Matriderm Flex) and full‐thickness skin grafts. The approach shown in this case report allows for quick healing, less donor‐site discomfort in comparison with dermatome‐harvested skin grafts, and very good aesthetic results, matching the surrounding skin thickness.
Role of the Systemic Immune‐Inflammation Index and Systemic Immune‐Response Index in the Prediction of Adverse Outcomes in Pregnant Women With Antiphospholipid Syndrome
Authors: Doğru Şükran , Ezveci Huriye , Yaman Fikriye Karanfil , Metin Ülfet Sena , Acar Ali 
Published: December 2024

ABSTRACTProblemThis study aims to evaluate the role of the systemic immune‐inflammation index (SII) and the systemic immune‐response index (SIRI) in predicting adverse perinatal outcomes (APO) in pregnant women with antiphospholipid syndrome (APS).MethodsThis is a retrospective case–control study at the tertiary center, between January 2015 and January 2023. The study included APS cases and a low‐risk control group. Pregnant women with APS (n = 52) and controls (n = 104) were compared between SII and SIRI values taken in the first trimester (1) and the last month before birth (2). It was examined whether these indexes predicted APO in cases with APS.ResultsIn the APS group, SII and SIRI values taken in the first trimester (1) and in the last month before birth (2) were significantly lower than in the control group (p = 0.015, p = 0.023, p = 0.001, p = 0.001, respectively). The small for gestational age (SGA) rate was 30.8% and the stillbirth rate was 11.5% in the APS group (p = 0.017, p = 0.001). The optimum cutoff values for SGA were 584.97 (75% sensitivity, 77.8% specificity), 688.50 (62.5% sensitivity, 62.9% specificity), and 1.02 (56.3% sensitivity, 77.8% specificity) for SII 1, SII 2, and SIRI 1, respectively. The optimum cutoff value for stillbirth was 1.23 for SIRI 2 (83.3% sensitivity, 89.1% specificity, p = 0.004).ConclusionPregnant women with APS had decreased blood indices in the first trimester and the last month before birth compared to the control group. In cases with APS, these indices can predict APOs like SGA and stillbirth.
Role of Decidual Natural Killer Cells in the Pathogenesis of Preeclampsia
Authors: Yue Shuang , Meng Jinlai 
Published: December 2024

ABSTRACTPreeclampsia is one of the most severe obstetric complications, yet its pathogenesis remains unclear. Decidual natural killer (dNK) cells, the most abundant immune cells at the maternal‐fetal interface, are closely associated with preeclampsia due to abnormalities in their quantity, phenotype, and function. This review summarizes the molecular mechanisms by which dNK cells regulate extravillous trophoblast (EVT) invasion, promote uterine spiral artery remodeling, and maintain immune tolerance. Furthermore, it explores how disruptions in these mechanisms and changes in the decidual microenvironment alter dNK cell properties, driving the progression of preeclampsia. Understanding the mechanisms of dNK cells and identifying potential therapeutic targets may provide new insights for clinical intervention.