bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genetically confirmed first records of an egg and a juvenile roundscale spearfish, Tetrapturus georgii
Authors: Freese Marko , Blancke Tina , Marohn Lasse , Pohlmann Jan‐Dag , Sundin Josefin , Wysujack Klaus , Hanel Reinhold 
Published: January 2025

AbstractThe roundscale spearfish (Tetrapturus georgii) is a poorly studied species with limited information available on its biology, ecology, and population status. Although the adult life stage of the species is morphologically distinguishable from closely related species such as the overexploited white marlin (Kajikia albida), misidentification is common, adding to the uncertainties connected with population assessments of these pelagic highly migratory species. Although genetic studies have recently confirmed its distinction from congeneric species, much of the reproductive biology and population dynamics of T. georgii remain unknown, underscoring the need for further research to guide conservation and management strategies. This study reports the first documented records of an egg and a juvenile T. georgii. Here, we provide photographs, morphological descriptions, and collection site data for genetically confirmed egg and juvenile specimens obtained during two multipurpose research surveys in the Sargasso Sea Subtropical Convergence Zone. These findings contribute new insights into the reproductive biology, early life stages, and ecology of this elusive species.
Systematic Review: Integrated Models of Care for Managing Irritable Bowel Syndrome
Authors: Warner Molly M. , Soliman Olivia Marie , Crichton Megan , Marshall Skye , Staudacher Heidi M. , Kelly Jaimon T. 
Published: January 2025

ABSTRACTBackgroundMultidisciplinary integrated models of care show promise for improving symptoms and quality of life (QoL) in adults with irritable bowel syndrome (IBS).AimsTo describe and evaluate the characteristics of integrated models of care for IBS and identify how digital health is being used in these models of care.MethodsFour databases were searched to March 2024 for studies that included adults with IBS who participated in multidisciplinary integrated models of care that delivered non‐pharmacological therapies. The template for intervention description and replication (TIDieR) checklist was used to appraise study quality and extract model of care characteristics, which were mapped against the Project INTEGRATE framework to establish topics.ResultsSixteen studies (6 randomized controlled trials, 2 quasi‐experimental, 8 cohort studies) reported 14 integrated models of care including 2165 patients of which 918 were IBS patients. Integrated models of care led to improved IBS symptoms (n = 11/13 models of care) and QoL (n = 6/9 models of care). Studies showed moderate compliance with the TIDieR checklist. Five topics were established: clinicians involved, therapies provided, location and mode of delivery, coordinating clinical partnerships, and sharing visions and values of integrated care. Most commonly, a gastroenterologist coordinated care with a psychologist, dietitian, and/or nurse in tertiary care. Psychological, dietary, and physical therapies were provided by n = 11, n = 8, and n = 3 integrated models of care, respectively. Six models of care provided joint consultations or group sessions. Four models of care used digital health such as telephone coaching or online modules.ConclusionsIntegrated models of care for IBS exhibited diverse characteristics including the clinicians involved, the therapies provided and the mode of delivery of each therapy. There is a need to evaluate the use of digital health and the delivery of integrated models of care in primary care settings.
The genomic secrets of invasive plants
Authors: Hodgins Kathryn A. , Battlay Paul , Bock Dan G. 
Published: January 2025

SummaryGenomics has revolutionised the study of invasive species, allowing evolutionary biologists to dissect mechanisms of invasion in unprecedented detail. Botanical research has played an important role in these advances, driving much of what we currently know about key determinants of invasion success (e.g. hybridisation, whole‐genome duplication). Despite this, a comprehensive review of plant invasion genomics has been lacking. Here, we aim to address this gap, highlighting recent discoveries that have helped progress the field. For example, by leveraging genomics in natural and experimental populations, botanical research has confirmed the importance of large‐effect standing variation during adaptation in invasive species. Further, genomic investigations of plants are increasingly revealing that large structural variants, as well as genetic changes induced by whole‐genome duplication such as genomic redundancy or the breakdown of dosage‐sensitive reproductive barriers, can play an important role during adaptive evolution of invaders. However, numerous questions remain, including when chromosomal inversions might help or hinder invasions, whether adaptive gene reuse is common during invasions, and whether epigenetically induced mutations can underpin the adaptive evolution of plasticity in invasive populations. We conclude by highlighting these and other outstanding questions that genomic studies of invasive plants are poised to help answer.
Redistributive Impacts of Civil War: The Case of Côte d'Ivoire
Authors: Hlasny Vladimir 
Published: January 2025

ABSTRACTMany least developed countries (LDCs) are plagued by recurring conflict. Conflict impedes sustainable development through various channels, creating conditions fomenting further conflict. Conflict has redistributive impacts, particularly when it erupts in resource‐rich countries. Between 2002 and 2011, Côte d'Ivoire faced off two spells of civil war (2002–2007 and 2010–2011) along geographic, religious and ethnic lines. We investigate how the civil war and the associated changes in the political balance impinged on economic outcomes of the affected groups at various income quantiles. Growth incidence curves before–after conflict illustrate the income changes of the respective socioeconomic groups. Accounting for distortions due to individual selection and general‐equilibrium spillovers, unconditional quantile regressions fitted by the means of recentered influence functions are used to isolate between‐group income gaps attributable to conflict. The results on microdata from 2002 to 2018 Household Living Standards Surveys confirm that as the political tide shifted, the economic fortunes of the affected groups turned. Previously marginalized communities—the northern, Gour and Mandé ethnic, and non‐Christian groups—have bridged some of their disadvantage related to their endowments and the market returns on them. These effects are clearest in the upper half of the income spectrum, leading to important changes in social order.
Development and Validation of the Invisibility Scale
Authors: Ebbrecht Christopher Kehlet , Bertelsen Preben 
Published: January 2025

ABSTRACTThe concept of social invisibility describes the devaluation of the perceived social and personal worth of an individual. This paper presents the theoretical foundation for this construct, and the development and validation of the “Invisibility Scale” capturing experiences of and needs for social (in)visibility within (i) intimate, (ii) legal, and (iii) communal relations. We developed and validated the Invisibility Scale in two studies. In Study I (n = 944), we formulated 80 items and tested their underlying factor structure using Exploratory Factor Analyses (EFA). In Study II (n = 846), we aimed to replicate the factor structure identified in Study I on a novel sample using Confirmatory Factor Analysis (CFA), and establish criterion‐related validity and construct validity using Structural Equation Modeling (SEM). Our results supported the development of two separate scales for measuring experiences of social invisibility (“Invisibility ScaleEXP”) and needs for social visibility (“Invisibility ScaleNEED”) Each scale consisted of 12 items (four items for each subfactor of intimate, legal, and communal relations). Evidence for construct validity between the Invisibility Scales and relevant constructs like Moral Disengagement, Sense of Coherence, and Violent Extremist Attitudes was mixed. Based on our findings, we present the two Invisibility Scales as preliminary validated measures of social invisibility. We encourage future research to replicate our findings, as well as looking more into other potentially mediating and moderating factors between social invisibility and its emotional, cognitive, and behavioral correlates.
The relationship between blood test results and vasovagal reactions: An intra‐individual comparative retrospective analysis of blood donor data in Japan
Authors: Chijiiwa Taeko , Hirata Akie , Okui Tasuku , Iwasaki Junko , Nakashima Naoki , Kumagawa Midori 
Published: January 2025

AbstractBackground and ObjectivesTo determine whether intra‐individual differences in pre‐donation blood test results were associated with vasovagal reactions (VVRs).Materials and MethodsThe study included donors who voluntarily donated 400 mL of whole blood at least twice during a 5‐year blood collection period of the Japanese Red Cross, including both donations with and without a VVR. A conditional logistic regression analysis by age group and sex was conducted, using each donor as a stratum, together with an analysis of deviance to test the significance of including an interaction term between age group and blood data in the regression model.ResultsA total of 1873 donors were included in the analysis. Haemoglobin, haematocrit, total protein and albumin values prior to donation were higher when a VVR was observed than when it was not for each age group and sex. The regression analysis showed significant positive associations between each of these blood parameters and VVR in all combinations of age groups and sex. A particularly strong positive association between haemoglobin and VVRs is seen in women aged ≥50 years (odds ratio, OR [95% confidence interval, CI]: 1.844 [1.457, 2.333]).ConclusionHaemoglobin, haematocrit, total protein and albumin levels within individual donors were significantly higher at donation with a VVR. This was most notable in women aged ≥50 years. Comparing the pre‐donation haemoglobin value with past values in the same donor at the donation site would help raise awareness of the risk of VVRs.
Long-term effects of duodenal mucosal resurfacing and liraglutide on glycaemic control in patients with type 2 diabetes
Authors: Busch Celine B E , Rubingh Julia , van Baar Annieke C G , Nieuwdorp Max , Bergman Jacques J G H M 
Published: January 2025

IntroductionEndoscopic duodenal mucosal resurfacing (DMR) induces mucosal regeneration through hydrothermal ablation. Studies have shown that DMR improves hyperglycaemia in patients with type 2 diabetes. The INSPIRE study (n=16) aimed to eliminate insulin by combining DMR with a glucagon-like peptide-1 receptor agonist (GLP-1RA). At 18 months, 53% of patients were off insulin with adequate glycaemic control. This retrospective analysis evaluates long-term effects of DMR and GLP-1RA.Research design and methodsFourteen patients gave consent for the prolonged follow-up and data on glycaemic control, medication and DMR satisfaction were obtained via general practitioners. Primary endpoint was the number of patients off insulin with glycaemic control (haemoglobin A1c (HbA1c) ≤58 mmol/mol (7.5%)) at 4 years post DMR. Secondary endpoints were changes in HbA1c, fasting plasma glucose (FPG), weight, body mass index (BMI), use of glucose-lowering medications, treatment satisfaction and willingness to undergo DMR retreatment.ResultsNine out of 14 patients (64%) were off insulin at 4 years. Of these, five patients (36% of study population) were adequately controlled. HbA1c and FPG did not change significantly, whereas BMI decreased at 3 and 4 years. Among the responders at 12 months, there was 80% durability at 4 years. Patients rated the DMR procedure 9 out of 10 and 86% were willing to undergo DMR retreatment.ConclusionsDespite a stable number of patients remaining off insulin, a decrease in patients with adequate glycaemic control was observed. This suggests a slightly fading long-term DMR effect on glycaemia. High patient satisfaction and willingness for DMR retreatment indicate a promising avenue for further research.
Assessment of Saudi society’s attitudes towards implementing food polices of determining meal sizes and calories in food establishments
Authors: Alhelal Zahra M , Tami Suzan H 
Published: January 2025

AbstractIn 2020, the Saudi Food and Drug Authority introduced the Wajbati Rashaqati initiative to improve the quality of meals served in food establishments. The initiative included creating a menu for healthy meals with balanced nutritional elements; monitoring salt, sugar and fat content and reducing portion sizes. This study aimed to measure: (1) the awareness of Saudi adults regarding food calories and the method of calculating them; (2) the extent of Saudi adults’ knowledge of the initiative; (3) the readiness and extent of willingness of Saudi adults to commit to the initiative; (4) the relationship between Saudi adults’ body mass index (BMI), their calorie awareness and their readiness to implement the initiative and (5) the relationship between Saudi adults’ demographic factors, their calorie awareness and their readiness to implement the initiative. This cross-sectional study took place in the Eastern Region of Saudi Arabia, and the study data were collected through an electronic questionnaire. 519 Saudi adults participated in this study, and over 50% of the participants were female, married, with a bachelor’s degree and of a normal weight. Over 50% of the participants reported that they had knowledge of food calories and how to calculate their daily calories. Over 70% of the participants supported the initiative for determining the sizes and calories of foods available in food establishments, believing that this initiative might contribute to reducing obesity and chronic diseases. The χ2analysis revealed a significant correlation between participants’ BMI and their commitment to daily calorie needs (p=0.001). Based on regression analysis findings, individuals highly aware of their daily calorie intake were more likely to practice portion control, understand the health implications of dietary choices, and support the Wajbati Rashaqati initiative. Sociodemographic characteristics influenced individuals’ knowledge and endorsement of the initiative. Females, low-income participants and those with a high school diploma or less were more supportive, knowledgeable and informed about the initiative. The results of this study may contribute as a guide to implementing the initiative. It also may help decision makers to raise community awareness regarding dietary reference values, as well as to plan programmes to improve dietary behaviours.
Hand acceleration time (HAT) as a diagnostic tool in the assessment of haemodialysis access-induced distal ischaemia (HAIDI): study protocol for a prospective cohort study in the Barcelona south metropolitan area
Authors: Gonzalo Begoña , Videla Sebastian , Espinar Emma , Palacios Siloé , Herranz Carolina , Iborra Ortega Elena 
Published: January 2025

Introduction
Chronic hand ischaemia may affect some haemodialysis patients with an arteriovenous fistula (AVF) or graft (AVG), a condition known as haemodialysis access-induced distal ischaemia (HAIDI). Duplex ultrasonography (DUS) can provide comprehensive insights into anatomical and perfusion properties, and measuring the hand acceleration time (HAT) has been demonstrated to be sensitive within the framework of chronic upper limb ischaemia.

Methods and analysis
This single-centre, prospective cohort study will involve adult end-stage renal disease (ESRD) patients requiring either AVF or AVG for haemodialysis. The primary outcome will be HAT values (measured at the radial, ulnar and four hand arteries) before and after surgery. Secondary outcomes will include the incidence of HAIDI, vascular access patency, and the incidence of complications. A sample size of 126 subjects will be required to estimate HAIDI incidence with a 95% CI and ±5% precision. Statistical analyses will involve paired t-tests to compare preoperative and postoperative HAT values and determine optimal HAT cut-off values for diagnosing HAIDI.

Ethics and dissemination
This study was approved by the Bellvitge University Hospital Institutional Review Board (PR 201/23). Written informed consent will be obtained from all study participants before any study-related procedure is performed. Results will be published in peer-reviewed journals.

Trial registration number

ClinicalTrial.gov:
NCT06187207
Pre Results.
Suicide by suffocation among Asian American, Native Hawaiian and Pacific Islander Veterans in the USA (2012–2018)
Authors: Monteith Lindsey L , Kittel Julie A , Polzer Evan R , Holliday Ryan , Simonetti Joseph A , Hoffmire Claire A 
Published: January 2025

BackgroundSuicide rates have increased substantially among Asian American, Native Hawaiian and Pacific Islander (AANHPI) Veterans who are more likely to use suffocation as a suicide method than Veterans overall. This study examined demographic, healthcare and injury characteristics of AANHPI Veterans who died by suicide through suffocation and examined the contexts of these deaths. Analyses further examined if there were differences between AANHPI and non-AANHPI Veterans who died by suffocation suicide.MethodsThis mixed methods analysis used National Violent Death Reporting System (NVDRS) data from AANHPI (n=44) and non-AANHPI (n=3090) Veterans who died by suicide through suffocation (2012–2018).ResultsHanging comprised nearly all suffocation deaths, although ligature types varied extensively. Residence was the most common location of injury and death, with basements a more common location of death within the home among AANHPI Veterans, relative to a matched, non-AANHPI Veteran sample. There was a significantly higher proportion of females among AANHPI decedents. Additionally, AANHPI decedents were significantly less likely to have emergency medical services present, relative to non-AANHPI decedents. The majority of AANHPI decedents were discovered by family or an intimate partner.ConclusionsAddressing ligature suicide among AANHPI Veterans is necessary to ensure an equitable suicide prevention approach. Lethal means safety initiatives and postvention strategies that consider salient contextual factors (eg, location of death, discovery by loved ones) are warranted for this population. Considering the ubiquity of ligatures and ligature points, upstream suicide prevention approaches that address drivers of suicide risk are particularly important for preventing suicide among AANHPI Veterans.
Transvenous embolization of brain arteriovenous malformations featuring multiple draining veins with 4D-DSA: a case series and technical insights
Authors: de Oliveira Souza Natalia Vasconcellos , Lima Vinicius Moreira , Rouchaud Aymeric , Saleme Suzana , Mounayer Charbel 
Published: January 2025

BackgroundHemorrhage is a major complication of brain arteriovenous malformations (AVMs) embolization, which can be related to persistent arteriovenous shunts that were not completely occluded during the embolization. In transvenous embolization (TVE) this risk is deemed higher for AVMs larger than 3 cm featuring multiple veins of drainage. Herein, we will discuss a few selected cases where brain AVMs with more than one draining vein were deemed safe for curative embolization with advanced endovascular techniques after a careful anatomical study through the four dimensional-digital subtraction angiography (4D-DSA) imaging.MethodsFour brain AVMs with more than one draining vein were selected from our database. A curative embolization through advanced endovascular techniques with curative intent was planned with the 4D-DSA. Immediate and 6 month angiographic controls are provided, as well as post-procedure MRI.ResultsAll 4 cases were successfully embolized, with stable 6 month angiographic controls. Although multiple draining veins were present, the 4D-DSA allowed the identification of favorable venous anatomy, such as a connection point between draining veins in case 1, as well as a main draining vein in cases 2 and 3. Case four is an exception to this, and although the AVM was cured patient presented asymptomatic ischemia after treatment. The anatomical insights gained through 4D-DSA imaging and the advanced endovascular techniques employed are discussed in detail.ConclusionBrain AVMs with multiple draining veins may behave like featuring a single draining vein, which can be identified through a careful anatomical study in the 4D-DSA, highlighting its importance for a safe endovascular treatment.
Telemedicine in Italy: Healthcare authorization profiles in the modern medico-legal reading
Authors: Bolcato Vittorio , Basile Giuseppe , Bianco Prevot Luca , Fassina Giovanni , Rapuano Silvia , Brizioli Enrico , Tronconi Livio P. 
Published: January 2025

Background The ruling n. 38485, 20 June 2019, of the Italian Supreme Court, III criminal section, addressed by the perspective of the law the very sensitive and new issue of telemedicine. Objective This commentary deals with the issue of authorization of telemedicine activities by the health authority, starting from the Italian Court of Criminal Cassation, III section, decision n. 38485/2019. The case law explored the authorization of a health point, which carries out telemedicine services. Methods Starting from the perspective discussed by Italian health regulations, the paper examines how the health act could be defined, with the possibilities offered by telecommunications, and how it now relates legally to the physical place where it takes place. Results Even if telemedicine opens the way to virtual spaces of health practice, the Ministry of Health Italian Guidelines pose functional and logistical issues to guarantee users’ safety and health care system accountability. Then, functional requirements for health legitimate practice, and their continuous monitoring, together with the responsibilities of the service centers, health professionals and health facilities, are discussed. Conclusion The questioning of States’ health law, in a broad health system such as that of the Europe, characterized by autonomous health regulations, is extremely important for cross-border health policy with telemedicine, as overall regulatory compliance in health care is the ground criterion for risk prevention and patient safety, to be properly verified.