bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stop and start control at work: Differential validity of two types of self‐control for work behavior and emotion regulation
Authors: van Hooft Edwin A. J. , Kreemers Loes M. 
Published: December 2021

AbstractSelf‐control enables people to regulate their emotions, desires, cognitions, and behaviors. We distinguish between two types of self‐control (i.e., inhibitory/stop‐control and initiatory/start‐control), revised De Boer et al.'s stop/start‐control scales (Study 1), and examined their value in predicting work‐related behavior and emotion regulation among employees in a two‐wave design (Study 2). The findings show that stop‐ and start‐control have differential predictive validity: Stop‐control relates negatively to counterproductive work behavior and positively to expressive suppression, whereas start‐control relates positively to increasing challenging job demands (job crafting), cognitive reappraisal, and positive framing. Moreover, usefulness analyses supported the incremental validity of the narrow stop/start‐control facets beyond general trait self‐control. These findings illustrate the value of stop/start‐control at work, further substantiate stop/start‐control theory, and suggest organizations should take stop/start‐control into account (e.g., in personnel selection, job design).
Increasing Helicobacter pylori clarithromycin resistance in Australia over 20 years
Authors: Schubert Jonathon P. , Warner Morgyn S. , Rayner Christopher K. , Roberts‐Thomson Ian C. , Mangoni Arduino A. , Costello Sam , Bryant Robert V. 
Published: December 2021

AbstractBackgroundHelicobacter pylori infection is responsible for considerable morbidity and mortality worldwide, and eradication rates are falling in many countries, primarily due to clarithromycin and metronidazole resistance.AimsThere is a paucity of contemporary Australian data, which we sought to address by evaluating local rates of resistance of H. pylori to amoxicillin, clarithromycin, metronidazole and tetracycline over the past 20 years.MethodsAll gastric biopsy specimens collected at endoscopy to detect H. pylori infection at a single centre underwent routine culture and antibiotic susceptibility testing between 1998 and 2017. Specimens from 12 842 patients were cultured for H. pylori, of which 1473 positive cultures were tested for antibiotic susceptibility.ResultsAntibiotic resistance to clarithromycin increased by 3.7% per year (incidence rate ratio [IRR] 1.037; P = 0.014) over 20 years, with a corresponding 5.0% annual increase in minimum inhibitory concentration (MIC) (odds ratio 1.050; P < 0.001). Since 2010, average clarithromycin resistance has exceeded 20%, with >25% of isolates resistant in the past 2 years of data capture. In contrast, rates of resistance to metronidazole (35.3%), amoxicillin (0.14%) and tetracycline (0.34%) and their MIC have remained stable. Review of a representative sample (n = 120; 8%) of these patients revealed that only 5% had documented prior H. pylori eradication therapy.ConclusionsOver the past 20 years there has been a substantial rise in clarithromycin resistance, with stable metronidazole resistance and low rates of resistance to amoxicillin and tetracycline. Current first‐line H. pylori eradication therapy may fail to achieve adequate eradication rates, and optimal first‐line therapy in Australia should be revisited.
Happy, sad, or yucky? Parental emotion talk with infants in a book‐sharing task
Authors: Ruba Ashley L. , Kalia Vrinda , Wilbourn Makeba Parramore 
Published: December 2021

AbstractWhile preschoolers consistently produce and use labels for happy and sad emotional states, labels for other emotional states (e.g., disgust) emerge much later in development. One explanation for these differences may lie in how parents first talk about these emotions with their children in infancy and toddlerhood. The current study examined parent talk about different emotions (i.e., happiness, sadness, anger, fear, and disgust) in a book‐sharing task with their 12‐ to 24‐month‐old infants. Parental talk on each emotion page was coded for both quantity and quality of emotion talk. We found that, rather than labeling or asking questions about disgust emotional states, parents instead elaborated on and asked questions about the context of disgust pictures. In contrast, parents frequently labeled happy and sad emotional states and behaviors. Parental use of causal questions related to infants’ productive emotion vocabularies. These different narrative styles may partly explain why older children acquire emotion labels for “happy” and “sad” much earlier than “disgust.”
In situ combined stress‐ and temperature‐dependent Raman spectroscopy of Li‐doped (Na,K)NbO3
Authors: Khansur Neamul H. , Eckstein Udo R. , Bergler Michael , Martin Alexander , Wang Ke , Li Jing‐Feng , Cicconi Maria Rita , Hatano Keiichi , Kakimoto Ken‐ichi , de Ligny Dominique , Webber Kyle G. 
Published: December 2021

AbstractExternal thermal, electrical, and mechanical fields can induce structural phase transitions in lead‐free Li‐modified Na0.5K0.5NbO3 ferroelectrics, which significantly influence the macroscopic electromechanical response. In particular, the relative stability of the polar monoclinic (or orthorhombic) and tetragonal phases under temperature and stress is critical to realize the ferroelectric and piezoelectric response. In this study, the effect of mechanical and thermal fields on the local structure in the vicinity of the monoclinic‐tetragonal (M‐T) phase boundary was investigated using a novel in situ combined uniaxial compressive stress‐ and temperature‐dependent Raman spectroscopy experimental arrangement. Experiments were performed up to 300°C and −200 MPa, clearly demonstrating stress‐induced M‐T phase transition in Li‐modified Na0.5K0.5NbO3. A stress‐temperature phase diagram has been established based on the change in vibrational modes. It was possible to correlate the relative permittivity singularities previously observed to a given stage of the M‐T phase transition using ratio between characteristic Raman band areas. In addition, the measurement method reported here can be applied to other functional ceramics to investigate the influence of mechanical fields on local structure.
Candida albicans biofilm formation and growth optimization for functional studies using response surface methodology
Authors: Sadanandan Bindu , Vaniyamparambath Vijayalakshmi , Lokesh K. N. , Shetty Kalidas , Joglekar Amruta P. , Ashrit Priya , Hemanth Beena 
Published: December 2021

Abstract

Aim
Optimization of Candida albicans growth and biofilm formation is essential for understanding the recalcitrance of this pathogen to advance functional analysis on hospital tools and material surfaces. Optimization and quantification of biofilm have always been a challenge using the conventional one variable at a time (OVAT) method. The present study uses central composite design-based response surface methodology for optimization of conditions to induce growth and biofilm formation in Candida albicans on polystyrene microtiter plates.

Methods and Results
Statistical software package, Stat Soft®, STASTICA version 12.6 was used for data analysis. The variables considered in the design matrix were media pH, temperature, incubation period, shaker speed and inoculum size. A four-pronged quantification approach with XTT assay (cell viability), crystal violet assay (biofilm), calcofluor white assay and wet/dry weight measurements (cell mass) was used to understand different aspects of biofilm formation. Cell viability and cell mass were inversely related; however, biofilm was independent of these two factors. The study also highlighted the fact that foetal bovine serum does not significantly contribute to cell adhesion and in turn in vitro biofilm formation in some of the cultures.

Conclusions
A high-throughput optimization of C. albicans growth and biofilm formation on polystyrene microplate has been developed and validated.

Significance and Impact of Study
This is a first time approach to optimize the interaction of parameters for C. albicans biofilm formation using RSM. Heterogeneity in growth conditions for local strains of C. albicans clinical isolates was observed. This microtiter plate-based method can be used for future screening of therapeutics for the control of C. albicans.
Impact of mean blood pressure and blood pressure variability after diagnosis of mild cognitive impairment and risk of dementia
Authors: de Havenon Adam , Muddasani Varsha , Anadani Mohammad , Prabhakaran Shyam 
Published: December 2021

AbstractHypertension and increased blood pressure variability (BPV) are associated with the development of dementia. However, previous studies did not focus on the risk of dementia among participants with mild cognitive impairment (MCI) and controlled blood pressure level. To address this limitation, the authors performed a post‐hoc analysis of SPRINT MIND participants diagnosed with MCI (mean Montreal Cognitive Assessment score at diagnosis 16.1±3.1). The primary outcome was subsequent diagnosis of probable dementia. The exposure was mean blood pressure and BPV following MCI diagnosis until the end of follow‐up or a dementia event (mean follow‐up 2.6±1.2 years). The primary outcome occurred in 76/516 (14.7%) patients. The mean blood pressure was not significantly higher in participants who developed dementia. In the lowest quartile of BPV (systolic standard deviation), the rate of dementia was 8.5% (11/129), while in the highest quartile it was 21.7% (28/129). The highest quartile of systolic BPV had an adjusted hazard ratio for dementia of 2.73 (95% CI, 1.31–5.69) and for diastolic BPV it was 2.62 (95% CI, 1.26–5.47). In SPRINT MIND participants, the authors found that increased BPV after MCI diagnosis was associated with incident probable dementia during subsequent follow‐up.
Risk factors for nonfatal self‐harm and suicide among adolescents: two nested case–control studies conducted in the UK Clinical Practice Research Datalink
Authors: Cybulski Lukasz , Ashcroft Darren M. , Carr Matthew J. , Garg Shruti , Chew‐Graham Carolyn A. , Kapur Nav , Webb Roger T. 
Published: December 2021

BackgroundThe characteristics of adolescents who die by suicide have hitherto been examined in uncontrolled study designs, thereby precluding examination of risk factors. The degree to which antecedents of nonfatal self‐harm and suicide at young age differ remains unknown.MethodWe delineated two nested case–control studies of patients aged 10–19 years using the Clinical Practice Research Datalink with interlinked hospital and national mortality records. Cases were adolescents who between 1st January 2003 and 31st December 2018 had died from suicide (N = 324) – study 1; experienced their first self‐harm episode (N = 56,008) – study 2. In both studies, cases were matched on sex, age and practice‐level deprivation quintile to 25 controls. By fitting conditional logistic regression, we examined how risks varied according to psychiatric diagnoses, prescribed psychotropic medication, patterns of clinical contact and area‐level deprivation.ResultsSuicides occurred more often among boys (66%), but self‐harm was more common in girls (68%). Most individuals who self‐harmed or died from suicide presented to their GP at least once in the preceding year (85% and 75% respectively). Only a third of cases had one of the examined diagnostic categories recorded. Depression was most strongly associated with elevated risks for both outcomes (self‐harm: OR 7.9; 95% CI 7.8–8.2; suicide: OR 7.4; 95% CI 5.5–9.9). Except for autism spectrum disorder, all other diagnostic categories were linked with similar risk elevations for self‐harm as for suicide. Whilst self‐harm risk rose incrementally with increasing levels of area‐level deprivation, suicide risks did not.ConclusionsWe observed few marked differences in risk factor profiles for nonfatal self‐harm versus suicide. As most adolescents who had harmed themselves or died by suicide were known to services in the preceding year, their underlying pathology may not be adequately identified and treated. Our findings highlight the need for a multiagency approach to treatment and prevention.
Digital dermoscopy monitoring of melanocytic lesions: Two novel calculators combining static and dynamic features to identify melanoma
Authors: Zenone M. , Zocchi L. , Moccia C. , Passerini S.G. , Sanavia T. , Fariselli P. , Broganelli P. , Ribero S. , Maule M. , Quaglino P. 
Published: December 2021

AbstractBackgroundEarly diagnosis is the most effective intervention to improve the prognosis of cutaneous melanoma. Even though the introduction of dermoscopy has improved the diagnostic accuracy, it can still be difficult to distinguish some melanomas from benign melanocytic lesions. Digital dermoscopy monitoring can identify dynamic changes of melanocytic lesions: To date, some algorithms were proposed, but a universally accepted one is still lacking.ObjectivesTo identify independent predictive variables associated with the diagnosis of cutaneous melanoma and develop a multivariable dermoscopic prediction model able to discriminate benign from malignant melanocytic lesions undergoing digital dermoscopy monitoring.MethodsWe collected dermoscopic images of melanocytic lesions excised after dermoscopy monitoring and carried out static and dynamic evaluations of dermoscopic features. We built two multivariable predictive models based on logistic regression and random forest.ResultsWe evaluated 173 lesions (65 cutaneous melanomas and 108 nevi). Forty‐two melanomas were in situ, and the median thickness of invasive melanomas was 0.35 mm. The median follow‐up time was 9.8 months for melanomas and 9.1 for nevi. The logistic regression and random forest models performed with AUC values of 0.87 and 0.89, respectively, were substantially higher than those of the static evaluation models (ABCD TDS score, 0.57; 7‐point checklist, 0.59). Finally, we built two risk calculators, which translate the proposed models into user‐friendly applications, to assist clinicians in the decision‐making process.ConclusionsThe present study demonstrates that the integration of dynamic and static evaluations of melanocytic lesions is a safe approach that can significantly boost the diagnostic accuracy for cutaneous melanoma. We propose two diagnostic tools that significantly increase the accuracy in discriminating melanoma from nevi during digital dermoscopy monitoring.
Ichthyosis, psoriasiform dermatitis, and recurrent fungal infections in patients with biallelic mutations in PERP
Authors: Youssefian L. , Khodavaisy S. , Khosravi‐Bachehmir F. , Park J.S. , Saeidian A.H. , Mahmoudi H. , Saffarian Z. , Naraghi Z.S. , Kamyab‐Hesari K. , Zeinali S. , Vahidnezhad H. , Uitto J. 
Published: December 2021

AbstractBackgroundGermline autosomal dominant and autosomal recessive mutations in PERP, encoding p53 effector related to PMP‐22 (PERP), a component of epidermal desmosomes, have been associated with a spectrum of keratodermas. Monoallelic nonsense mutations cause Olmsted syndrome with severe periorificial keratoderma and palmoplantar keratoderma (PPK). Biallelic recessive frameshift and missense mutations are associated with milder forms of the disease, including generalised erythrokeratoderma and PPK.ObjectivesTo add new insights into the genotype‐phenotype correlations as a consequence of PERP mutations and to provide a comprehensive review of the literature.MethodsAmong 26 previously unresolved families within a cohort of 180 extended Iranian families with syndromic or non‐syndromic ichthyosis, two families with shared clinical features were examined by whole‐exome sequencing and genome‐wide homozygosity mapping. Mycological and dermatopathological studies were performed to further characterise their atypical phenotypic presentations.ResultsIn two unrelated multiplex consanguineous families affected by ichthyosis, two novel biallelic PERP variants, NM_022121.5, c.89T > C, p.Leu30Pro and c.466G > C, p.Gly156Arg, located inside of genomic homozygosity regions of the probands were detected. Interestingly, some patients had areas of scaly psoriasiform plaques on the background of generalised ichthyosis that appeared during active cutaneous fungal infections. Mycological examinations of these lesions revealed infections caused by Candida albicans, Epidermophyton floccosum, or Trichophyton rubrum. Histopathology of the psoriasiform lesions shared some features with psoriasis, which when combined with clinical presentation, led to incorrect diagnosis of guttate psoriasis or pustular psoriasis.ConclusionsPERP variants in ichthyosis patients can confer susceptibility to recalcitrant cutaneous fungal infections. Additionally, patients with episodic psoriasiform dermatitis in the setting of keratoderma should be considered for PERP genotyping and cutaneous fungal examinations.
“What else can we do?”—Provider perspectives on treatment‐resistant depression in late life
Authors: Hamm Megan E. , Karp Jordan F. , Lenard Emily , Dawdani Alicia , Lavretsky Helen , Lenze Eric J. , Mulsant Benoit H. , Reynolds Charles F. , Roose Steven P. , Brown Patrick J. 
Published: December 2021

AbstractBackgroundTreatment‐resistant depression in late‐life (TRLLD) is common. Perspectives of primary care providers (PCPs) and psychiatrists treating TRLLD could give insights into the challenges and potential solutions for managing this condition.MethodsTo identify perspectives of providers who treat TRLLD, we conducted a qualitative descriptive study using semi‐structured interviews with providers treating older adults with TRLLD in five locations across North America (i.e., Los Angeles, New York City, Pittsburgh, St. Louis, and Toronto). We conducted semi‐structured interviews with 50 care providers (24 primary care providers [PCPs], 22 psychiatrists, and 4 depression care managers). Interviews elicited providers' perspectives on treatment options for TRLLD, including treatment within the primary care setting and referral to psychiatry, and sought suggestions for improvement.ResultsWe identified four themes. (1) Treating TRLLD takes an emotional toll on providers; (2) existing psychiatric services are inadequate to meet the needs of patients with TRLLD, mainly because of lack of access; (3) PCPs often attempt to treat TRLLD, even when they are not comfortable doing so; and (4) to better meet the needs of patients with TRLLD, providers recommend integrated care models involving PCPs, psychiatrists, and psychotherapists, potentially made more feasible by the growth of telehealth.ConclusionsFindings from these qualitative interviews show the challenges in providing care for TRLLD. These findings can guide knowledge dissemination to psychiatrists, PCPs, policy‐makers, and other stakeholders involved in the mental health system. They can also inform structural changes to clinical practice that may increase the implementation of the best treatment strategies across settings to improve long‐term outcomes for TRLLD.
Causes of death in neotropical primates in Rio Grande do Sul State, Southern Brazil
Authors: Ehlers Luiza P. , Slaviero Mônica , Bianchi Matheus V. , de Mello Lauren S. , De Lorenzo Cíntia , Surita Lívia E. , Alievi Marcelo M. , Driemeier David , Pavarini Saulo P. , Sonne Luciana 
Published: December 2021

AbstractBackgroundAnthropogenic disturbances are the main threats to nonhuman primates conservation, and infectious diseases may also play a key role in primate population decline. This study aimed to determine the main causes of death in neotropical primates.MethodsA retrospective study of post‐mortem examinations was conducted on 146 neotropical primates between January 2000 and December 2018.ResultsConclusive diagnoses were obtained in 68.5% of the cases, of which 59 corresponded to non‐infectious causes and 41 to infectious diseases. Trauma was the main cause of death (54/100), with anthropogenic stressors caused by blunt force trauma injuries (collision with vehicles) and puncture wound injuries associated with interspecific aggression (dog predation) were the most common factors. Other causes of death included bacterial diseases (27%), followed by parasitic diseases (12%), neoplasms (2%), and viral diseases (2%).ConclusionsFree‐ranging primates were mostly affected by non‐infectious causes, while captive primates were by infectious conditions.
Sec3 exocyst component knockdown inhibits axonal formation and cortical neuronal migration during brain cortex development
Authors: Bustos Plonka Florentyna , Sosa Lucas J. , Quiroga Santiago 
Published: December 2021

AbstractNeurons are the largest known cells, with complex and highly polarized morphologies and consist of a cell body (soma), several dendrites, and a single axon. The establishment of polarity necessitates initial axonal outgrowth in concomitance with the addition of new membrane to the axon's plasmalemma. Axolemmal expansion occurs by exocytosis of plasmalemmal precursor vesicles primarily at the neuronal growth cone membrane. The multiprotein exocyst complex drives spatial location and specificity of vesicle fusion at plasma membrane. However, the specific participation of its different proteins on neuronal differentiation has not been fully established. In the present work we analyzed the role of Sec3, a prominent exocyst complex protein on neuronal differentiation. Using mice hippocampal primary cultures, we determined that Sec3 is expressed in neurons at early stages prior to neuronal polarization. Furthermore, we determined that silencing of Sec3 in mice hippocampal neurons in culture precluded polarization. Moreover, using in utero electroporation experiments, we determined that Sec3 knockdown affected cortical neurons migration and morphology during neocortex formation. Our results demonstrate that the exocyst complex protein Sec3 plays an important role in axon formation in neuronal differentiation and the migration of neuronal progenitors during cortex development.
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Effects of art consumption on consumerwell‐being
Authors: An Donghwy , Jeong Bo‐ram , Youn Nara 
Published: December 2021

AbstractThis research shows that consumers' experience of art, including artistic commercial products, enhances consumers' well‐being by inducing a sense of inspiration. Prior research in neuroscience and psychology has documented that participating in art and culture programs enhances individuals' well‐being, but there is a shortage of empirical evidence documenting the effect of consumers' art appreciation as products and services on well‐being or the cognitive mechanism underlying that effect. Our five studies, based on an administrative dataset (Study 1) and laboratory experiments (Studies 2a–2d), show that consumers' experience of art in daily life increases consumers' well‐being. Furthermore, consumers' experience of art induces inspiration, which in turn enhances subjective well‐being (Studies 2b and 2c), and consumer well‐being (Study 2d). Critically, that effect remained significant across various forms of art, including paintings, song lyrics, and sculpture, and extended to commercial products such as computer screen saver and handbags depicting artistic images.
Stock Market and No‐Dividend Stocks
Authors: ATMAZ ADEM , BASAK SULEYMAN 
Published: December 2021

ABSTRACTWe develop a stationary model of the aggregate stock market featuring both dividend‐paying and no‐dividend stocks within a familiar, parsimonious consumption‐based equilibrium framework. We find that such a simple feature leads to profound implications supporting several stock market empirical regularities that leading consumption‐based asset pricing models have difficulty reconciling. Namely, the presence of no‐dividend stocks in the stock market leads to a lower correlation between stock market returns and the aggregate consumption growth rate, a nonmonotonic and even negative relation between the stock market risk premium and its volatility, and a downward‐sloping term structure of equity risk premia.