bluuebunny/crossref_metadata_2025_split huggingface dataset:
Motivation and the careers of agricultural entrepreneurs in Ivory Coast
Authors: Milot-Lapointe Francis , Boua Sika Joëlle Prisca , St-Jean Etienne 
Published: August 2021

Purpose
Following an incursion into the business world as an entrepreneur, many people go back to being salaried workers or unemployed. Using self-determination theory (SDT), this study aims to test the effects of self-determined motivation of Ivorian agricultural entrepreneurs on career retention, career satisfaction and subjective well-being.

Design/methodology/approach
The sample under study consisted of 171 agricultural entrepreneurs in the Ivory Coast who owned their businesses. Research hypotheses were tested using structural equation modelling.

Findings
The findings reveal that the degree of self-determination in the motivation of Ivorian agricultural entrepreneurs does not have a direct effect on their intention as to whether or not to remain an entrepreneur. The findings nevertheless show that the more the degree of motivation of Ivorian agricultural entrepreneurs is self-determined, the greater satisfaction they experience with their entrepreneurial career and the higher their subjective well-being. The findings also show that satisfaction with the entrepreneurial career is a predictor of career retention among Ivorian agricultural entrepreneurs. In addition, career retention and subjective well-being are reciprocally linked, as are subjective well-being and career satisfaction.

Practical implications
Career retention of agricultural entrepreneurs in the Ivory Coast can be achieved through career satisfaction and self-determined motivation.

Originality/value
Based on previous studies on SDT in an organizational context, this study is, to the best of the knowledge, the first to have tested a theoretical model that can explain career retention, career satisfaction and subjective well-being among entrepreneurs. This research brings to light these processes among agricultural entrepreneurs in Ivory Coast.
The modern transformation of family governance: co-evolve of family authority and family formal institution
Authors: Ma Jun 
Published: August 2021

PurposeThis paper aims to investigate the co-evolve relationship between informal relational governance (i.e. family involvement and personal authority) and family formal governance system in the process of growth and transformation. This co-evolve relationship is especially affected by the external institutional environment and market competition power. Thus, in the comprehensive process of deepening the reform and changing market, the modern transformation of family business means that rediscovery of unique superiority of family business and the core of this transformation is the governance of status privileges and private interests.Design/methodology/approachTo test the hypotheses, this paper uses the 9th Chinese Private Enterprise Survey in 2010. A total of 4,900 questionnaires are issued, 4,614 are recovered and the total recovery rate is 94.16%. After clean the data, the study obtained 1,239 samples. To overcome the possible existence of heteroscedasticity, this study uses the feasible generalized least squares (FGLS) to estimate the model. Besides, as for dummy dependent variables, this study uses logistics regression.FindingsThis paper makes an empirical test for the evolution of family governance driven by institutional change and organizational growth willingness in the process of growth and transformation, including a co-evolve relationship between family involvement and governance institution. Meanwhile, the empirical analysis comes to the conclusion that the institutional constraint to relational governance improves firm performance, which further promotes the modern transformation of family business governance.Practical implicationsIt is the key to transformation to the modern corporate organization that family business could beyond the intervention of the traditional nepotism, patriarchal authority and family will. The fundamental of this process is to take advantage of formal institutions to manage family power.Originality/valueThis paper discusses the modern transformation of the formal organization from the perspective of modern ideal dominant type proposed by Max Weber. Modern organization is a hybrid system of the non-personified and personified institution. The primary reason why modern organization suffered erosion and destruction is that informal institution (status and relationship network) were endowed with legal privileges and private interests in modern organization including family business. The governance of privileges and private interests has become the core issue that whether the family business could play an instrumental value and realize modern transformation successfully.
Trust and social network to boost tacit knowledge sharing with mediation of commitment: does culture moderate?
Authors: Umar Muhammad , Sial Maqbool Hussain , Ali Syed Ahmad , Bari Muhammad Waseem , Ahmad Muhammad 
Published: August 2021

Purpose
This paper aims to investigate the tacit knowledge-sharing framework among Pakistani academicians. The objective is to study trust and social networks as antecedents to foster tacit knowledge sharing with the mediating role of commitment. Furthermore, the moderating role of organizational knowledge-sharing culture is also examined.

Design/methodology/approach
The study applied a survey-based quantitative research design to test the proposed model. The nature of data are cross-sectional and collected with stratified random sampling among public sector higher education professionals of Pakistan. The total sample size for the present research is 247 respondents. The variance-based structural equation modeling technique by using Smart_PLS software is used for analysis.

Findings
Data analysis and results reveal that trust and social networks are significant predictors of tacit knowledge sharing among Pakistani academicians while commitment positively mediated the relationships. While the moderating role of organizational knowledge-sharing culture is also established.

Research limitations/implications
The current research explains tacit knowledge sharing among academics with fewer antecedents i.e. social network and trust with limited sample size and specific population. There is still a great deal of work to be done in this area. Hence, the study provides direction for including knowledge-oriented leadership and knowledge governance in the current framework. Moreover, the framework can be tested in different work settings for better generalization.

Practical implications
The study gives an important lead to practitioners for enhancing tacit knowledge sharing at the workplace through a robust social network of employees, building trust and boosting employees’ commitment, as well as through supportive organizational knowledge sharing culture.

Originality/value
The research comprehends the tacit knowledge sharing framework with theoretical arrangements of trust, social networks, commitment and culture in higher education workplace settings under the umbrella of social capital theory.
Risk of chronic spontaneous urticaria in reproductive‐aged women with abnormal uterine bleeding: A population‐based cohort study
Authors: Chen Tai‐Li , Yip Hei‐Tung , Wang Jen‐Hung , Chang Chi‐Han , Huang Ci , Hsu Chung‐Y. , Chang Chung‐Hsing 
Published: August 2021

AbstractWomen with abnormal uterine bleeding (AUB) have been reported to develop chronic spontaneous urticaria (CSU). Nevertheless, whether or not AUB women have an increased risk of CSU has not been examined in large‐scale epidemiologic studies. This study aimed to investigate the risk of CSU among reproductive‐aged women with AUB. A total of 79 595 patients and 79 107 propensity‐score matched controls were recruited from Taiwan’s National Health Insurance Research Database to conduct a nationwide cohort study. The Cox proportional‐hazard regression model was applied to examine the adjusted hazard ratios (aHR) and 95% confidence intervals (CI) for CSU in relation to AUB. We found that women with AUB had a higher risk for CSU (aHR = 1.83; 95% CI, 1.76–1.90) than women without AUB. Subgroup analyses revealed that AUB with an abnormal bleeding frequency (aHR = 1.70; 95% CI, 1.60–1.79), irregular bleeding (aHR = 1.80; 95% CI, 1.71–1.89), and intermenstrual bleeding (aHR = 1.65; 95% CI, 1.49–1.83) were associated with an increased risk of CSU compared with those without abnormalities. The Kaplan–Meier analysis revealed that the cumulative incidence of developing CSU was consistently higher in the AUB cohort than in the non‐AUB cohort during the entire follow‐up period (log‐rank test, p < 0.001). In conclusion, reproductive‐aged women with AUB were found to have a higher risk of developing CSU. This study emphasizes the importance of enquiring CSU patients about menstrual problems in clinical practice. Further consultation with obstetrician‐gynecologists may be beneficial.
Safety considerations of systemic Janus kinase inhibitors in atopic dermatitis applications
Authors: Chang Po‐Hsiung , Huang Sheng‐Fen , Chang Po‐Sheng , Yu Yu 
Published: August 2021

AbstractJanus kinase (JAK) inhibitors are emerging treatments for atopic dermatitis (AD). Due to this novel role as a therapeutic option for patients with AD, we aimed to review current evidence on the pathophysiology and the safety and adverse effects (AEs) of oral JAK inhibitors for the treatment of AD utilizing the key terms atopic dermatitis, JAK inhibitors, and adverse effect or event. Our study indicated that oral JAK inhibitors have a moderate safety profile for use in AD in several reviews and phase II or III clinical trials. Headaches, nausea, and nasopharyngitis are the most commonly reported systemic AEs. Furthermore, acne, herpes simplex, herpes zoster, and eczema herpeticum are the most commonly recorded dermatological AEs. Current evidence indicates JAK inhibitors may also have less association with some of the serious AEs, although there is potential for increased risk of asthma, acute pancreatitis, neutropenia, and thrombocytopenia. Whereas data remain limited for the long‐term safety of JAK inhibitor use in patients with AD, many ongoing clinical trials have promising preliminary results.
Climate influences productivity but not breeding density of wedge‐tailed eaglesAquila audaxin arid and mesic Western Australia
Authors: Cherriman Simon C. , Fleming Patricia A. , Shephard Jill M. , Olsen Penny D. 
Published: August 2021

AbstractLong‐term studies are required to reveal responses by long‐lived, top‐order predator populations to ongoing seasonal fluctuations. However, such investigations are rare in the Australian context. Between 2009 and 2019, the breeding density and productivity of an arid and a mesic wedge‐tailed eagleAquila audaxpopulation, each occupying an area of 2800 km2, were compared (11–98 pairs monitored annually). Breeding pairs spaced themselves evenly in both study areas, with no significant difference between the average arid zone nearest‐neighbour distance of 5.32 ± 1.98 km (n = 44) and that determined for the mesic zone (4.88 ± 2.32 km,n = 54). This similarity in spacing suggests a maximum average density is tolerated by these territorial raptors. By contrast, annual breeding success (proportion of pairs fledging young) and productivity (fledged young per pair) differed significantly between the two populations, with rainfall (but not temperature) influencing reproduction. In the arid zone, the proportion of successful pairs per occupied breeding home range was consistently low each year (mean = 12 ± 7% fledged broods per pair, range 0–26%) and positively correlated with annual rainfall. In the mesic zone, it was consistently high each year (mean = 69 ± 9%, range 57–91%) and not significantly correlated with annual rainfall. Overall productivity figures showed similar differences, with 0.13 and 0.77 fledglings per pair per year for arid (n = 9 years) and mesic (n = 11 years) eagles, respectively. Such low arid zone productivity, the lowest ever recorded for the species, could have long‐term implications in the face of the increased frequency of extreme weather events. That breeding density can be independent of climatic factors provides new insight into the way a largeAquilaspecies integrates with Australia’s predominantly arid environment. This study provides an important baseline data set for continued research on long‐term occupancy and productivity trends.
Health seeking behaviours and treatments received by Australian women with vulvodynia: A cross‐sectional survey
Authors: Mitchell Alice M. , Armour Mike , Chalmers K. Jane 
Published: August 2021

BackgroundVulvodynia is a condition characterised by pain in the vulva lasting more than three months and for which no obvious aetiology can be found. It affects around 8% of women and has significant negative impacts on quality of life. There is a paucity of research on healthcare management pathways and the use of evidence‐based treatments in an Australian community setting.AimsTo explore which healthcare professionals Australian women with vulvodynia seek treatment from, and which treatments are recommended, provided, or prescribed by these healthcare professionals.Materials and MethodsA cross‐sectional online survey was conducted from May 2019 to August 2019. Women were eligible to participate if they had been diagnosed with vulvodynia by a healthcare professional, were currently living in Australia, and were over 18 years old.ResultsFifty respondents meet the inclusion criteria, with a mean age of 30.5 years. On average, respondents reported seeing four different types of healthcare professionals in the management of their vulvodynia, with general practitioners (GPs) (98%), medical specialists (96%), and physiotherapists (80%) being the three most commonly consulted. Most respondents reported seeing multiple GPs (>87%), multiple medical specialists (>77%), and multiple physiotherapists (50%). The most commonly prescribed interventions were pelvic floor down‐training exercises (76%), topical (70%) and oral (70%) medication, and vulvodynia information (56%).ConclusionsAustralian women with vulvodynia seek help from several professionals and receive a variety of treatments for their pain. Of concern is many treatments that are being offered clinically have very little peer‐reviewed evidence of effectiveness in vulvodynia.
Outpatient vs inpatient Foley catheter induction of labor in multiparas with unripe cervixes: A randomized trial
Authors: Hamdan Mukhri , Shuhaina Shuib , Hong Jesrine Gek Shan , Vallikkannu Narayanan , Zaidi Syeda Nureena , Tan Yi Pin , Tan Peng Chiong 
Published: August 2021

AbstractIntroductionMultiparous labor inductions are typically successful, and the process can be rapid, starting from a ripened cervix with a predictable response to amniotomy and oxytocin infusion. Outpatient Foley catheter labor induction in multiparas with unripe cervixes is a feasible option as the mechanical process of ripening is usually without significant uterine contractions and well tolerated. Labor contractions can be initiated by amniotomy and titrated oxytocin infusion in the hospital for well‐timed births during working hours as night birth are associated with adverse events. We sought to evaluate outpatient compared with inpatient Foley catheter induction of labor in multiparas for births during working hours and maternal satisfaction.Material and methodsA randomized trial was conducted in the University of Malaya Medical Center. A total of 163 term multiparas (no dropouts) with unripe cervixes (Bishop score ≤5) scheduled for labor induction were randomized to outpatient or inpatient Foley catheter. Primary outcomes were delivery during “working hours” 08:00–18:00 h and maternal satisfaction on allocated care (assessed by 11‐point visual numerical rating score 0–10, with higher score indicating more satisfied). Clinical trial registration: ISRCTN13534944.ResultsComparing outpatient and inpatient arms, delivery during working hours were 54/82 (65.9%) vs. 48/81 (59.3%) (relative risk 1.1, 95% CI 0.9–1.4, p = 0.421) and median maternal satisfaction visual numerical rating score was 9 (interquartile range 9–9) vs. 9 (interquartile range 8–9, p = 0.134), repectively. Duration of hospital stay and membrane rupture to delivery interval were significantly shorter in the outpatient arm: 35.8 ± 20.2 vs. 45.2 ± 16.2 h (p = 0.001) and 4.1 ± 2.9 vs. 5.3 ± 3.6 h (p = 0.020), respectively. Other maternal and neonatal secondary outcomes were not significantly different.ConclusionsThe trial failed to demonstrate the anticipated increase in births during working hours with outpatient compared with inpatient induction of labor with Foley catheter in parous women with an unripe cervix. Hospital stay and membrane rupture to delivery interval were significantly shortened in the outpatient group. The rate of maternal satisfaction was high in both groups and no significant differences were found.
A trade‐off: Antimicrobial resistance and COVID‐19
Authors: Johnson Tess 
Published: August 2021

AbstractAs we combat the COVID‐19 pandemic, both the prescription of antimicrobials and the use of biocidal agents have increased in many countries. Although these measures can be expected to benefit existing people by, to some extent, mitigating the pandemic's effects, they may threaten long‐term well‐being of existing and future people, where they contribute to the problem of antimicrobial resistance (AMR). A trade‐off dilemma thus presents itself: combat COVID‐19 using these measures, or stop using them in order to protect against AMR. Currently, I argue, we are choosing to continue with these measures, and thus to prioritize combatting COVID‐19, without adequate ethical reflection on the AMR‐associated costs of these measures. I discuss the magnitude of the possible costs and benefits involved in making the trade‐off in favour of COVID‐19, and their distribution. I highlight two salient aspects of distribution that can help determine whether combatting COVID‐19 whilst exacerbating AMR produces justly distributed costs and benefits: distribution between current and future populations, and distribution between existing geographical populations. Adopting this account, I argue that based on the magnitude and distribution of costs and benefits of combatting COVID‐19, we have good reason to rethink this trade‐off, and instead consider prioritizing protecting current and future people against AMR, but jettisoning measures against COVID‐19 that also exacerbate AMR.
PDK2 leads to cisplatin resistance through suppression of mitochondrial function in ovarian clear cell carcinoma
Authors: Kitamura Sachiko , Yamaguchi Ken , Murakami Ryusuke , Furutake Yoko , Higasa Koichiro , Abiko Kaoru , Hamanishi Junzo , Baba Tsukasa , Matsumura Noriomi , Mandai Masaki 
Published: August 2021

AbstractOvarian clear cell carcinoma (CCC) exhibits an association with endometriosis, resistance to oxidative stress, and poor prognosis owing to its resistance to conventional platinum‐based chemotherapy. A greater understanding of the molecular characteristics and pathogenesis of ovarian cancer subtypes may facilitate the development of targeted therapeutic strategies, although the mechanism of drug resistance in ovarian CCC has yet to be determined. In this study, we assessed exome sequencing data to identify new therapeutic targets of mitochondrial function in ovarian CCC because of the central role of mitochondria in redox homeostasis. Copy number analyses revealed that chromosome 17q21‐24 (chr.17q21‐24) amplification was associated with recurrence in ovarian CCC. Cell viability assays identified an association between cisplatin resistance and chr.17q21‐24 amplification, and mitochondrion‐related genes were enriched in patients with chr.17q21‐24 amplification. Patients with high expression of pyruvate dehydrogenase kinase 2 (PDK2) had a worse prognosis than those with low PDK2 expression. Furthermore, inhibition of PDK2 synergistically enhanced cisplatin sensitivity by activating the electron transport chain and by increasing the production of mitochondrial reactive oxygen species. Mouse xenograft models showed that inhibition of PDK2 with cisplatin inhibited tumor growth. This evidence suggests that targeting mitochondrial metabolism and redox homeostasis is an attractive therapeutic strategy for improving drug sensitivity in ovarian CCC.
Developmental associations between risk‐taking and anxiety symptoms across ages 8–12 years
Authors: Tieskens Jacintha M. , Buil J. Marieke , Koot Susanne , van Lier Pol A. C. 
Published: August 2021

AbstractThis study explored the transactional association between anxiety symptoms and risk‐avoidance in Dutch elementary schoolchildren (N = 1200; 50% girls) across ages 8–12. Anxiety symptoms were obtained using self‐, peer‐, and teacher‐reports. Risk‐avoidance was measured using the Balloon Analogue Risk Task—Youth Version. Random‐intercept cross‐lagged panel models showed that, across informants, increases in anxiety symptoms predicted decreases in risk‐taking. Apart from minor exceptions, this effect was similar across sexes. For peer‐reports, the reverse path from decreases in risk‐taking to increased anxiety was also found. Overall, this study gives insight into the developmental link between symptoms of anxiety and risk‐avoidance which is important for early signaling and prevention as well as for our understanding of the consequences of childhood anxiety symptoms.
Measuring the quality of early childhood education: Associations with children’s development from a national study with the IMCEIC tool in Colombia
Authors: Maldonado‐Carreño Carolina , Yoshikawa Hirokazu , Escallón Eduardo , Ponguta Liliana Angélica , Nieto Ana María , Kagan Sharon Lynn , Rey‐ Guerra Catalina , Cristancho Juan Camilo , Mateus Angy , Caro Luz Angela , Aragon Carlos Andrés , Rodríguez Ana María , Motta Andrés 
Published: August 2021

AbstractNational‐level monitoring of quality of early childhood education (ECE) is key to achieving inclusive and equitable education. Most countries report structural quality while process characteristics are rarely observed at the national level. This study examined the associations between ECE and children's development in a middle‐income country using data from a nationally representative sample of public centers serving Colombian children (N = 3163; M = 4.3 years, 50% girls; 42% Mestizo, 16% White, 15% Afro‐Colombian, 4% Indigenous, 23% not reported). Descriptive findings evidenced low to moderate quality. Multilevel models showed several positive associations between structural and process quality and child outcomes. Results have implications for the existing literature and highlight the feasibility of quality monitoring in low‐ and middle‐income countries.