bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tren Penelitian Kepuasan Kerja Pegawai Rumah Sakit dalam Jurnal Kesehatan di Indonesia
Authors: Asmaryadi Asmaryadi , Nurfadhilah  , Nurintan Malik  , A. Karlina Askarini Makkasau  , Ra'idatusakinah M. Nur  , Ismi  
Published: February 2025

Kepuasan pegawai dalam lingkungan rumah sakit merupakan elemen krusial yang mendukung kinerja dan kesejahteraan pegawai, serta dapat memastikan ketersediaan layanan kesehatan berkualitas tinggi. Penelitian ini menggunakan metode analisis konten pada sejumlah artikel yang telah dipublikasikan di jurnal kesehatan dan terakreditasi Sinta 1 dan Sinta 2 pada tahun 2021 sampai 2025, dengan kepuasan pegawai sebagai fokus utama. Hasil penelitian menunjukkan bahwa jumlah publikasi yang berfokus pada kepuasan pegawai berfluktuasi setiap tahun. Di antara publikasi tersebut, semua penelitian menggunakan metode kuantitatif. Subyek penelitian didominasi oleh Perawat dengan instrumen pengumpulan data menggunakan kuesioner. Teknik analisis multivariat seperti Structural Equation Modelling (SEM) dan Path Analysis paling sering digunakan. Adapun faktor-faktor yang mempengaruhi kepuasan pegawai adalah kepemimpinan, kompensasi finansial, stres kerja, peluang pengembangan diri, sumber daya dan work engangement. Sedangkan, kepuasan kerja mempengaruhi turnover intention dan kinerja. Sehingga direkomendasikan untuk mengeksplorasi lebih lanjut mengenai studi kepuasan pegawai dengan menggunakan metode kualitatif dan mix methods, khususnya pada profesi selain perawat di rumah sakit.
Analysis of Cost and Time To Complete of Office Project with The Earned Value Method
Authors: Nailufar Linda , Witjaksana Budi , Wulandari Esti 
Published: February 2025

The rescheduling of the initial schedule carried out on the Bahtera Elang Perak Indonesia Office Construction project has an impact on increasing the duration of work causing the project completion target to be delayed from the time it should be. Increasing the project completion target can affect the amount of costs incurred. The contract value for this office construction project is Rp. 13,908,226,157 with a work duration of 43 weeks to 54 weeks. The current condition of work progress at week 31 is -0.225% while the total actual cost or that has been incurred during the work is Rp. 3,191,740,254. To overcome this, an analysis is carried out on the value of the estimate at complete (EAC) and time estimate (TE) of the Surabaya BEPI Office Construction Project using the earned value method. This method combines the elements of cost, schedule, and work performance. The earned value method aims to determine the estimated cost and time of project completion. From the results of the analysis conducted in the 41st week, it was obtained that the estimated cost and time to complete the project implementation (EAC) was 14,289,833,105, - and the estimated time (TE) was 499 days, which was 121 days later than the original schedule.
Capital Structure Analysis: Key Financial Indicators in Manufacturing
Authors: Sianturi Antar MT , Siahaan Magda , Pradipta Arya 
Published: February 2025

This study focuses on how liquidity, asset composition, free cash flow, and profitability impact capital structure. It also explores how profitability can affect the relationship between liquidity, asset composition, and free cash flow with capital structure. The study focused on collecting information from 50 manufacturing firms that are publicly traded on the Indonesia Stock Exchange over a period of three years, totaling 121 data points. The data analysis method uses multiple linear regression with the help of the Statistical Package for Social Sciences program. The study's findings suggest that there is some evidence to support the idea that liquidity has a negative impact on capital structure. The asset structure variable and the free cash flow variable do not affect capital structure. The profitability variable is proven to strengthen the negative effect of liquidity on capital structure. Nevertheless, it is unable to enhance the favorable impact of the composition of assets and the detrimental impact of surplus cash flow on the firm's financial structure. According to the research, it is suggested that the board members and executives of the organization should be responsible for optimizing resources and driving up the company's earnings; investors who want to invest in manufacturing companies should do an investment assessment.
Ethanol neuronotoxicity in the embryonic chick brain in ovo and in culture: Interaction of the neural cell adhesion molecule (NCAM)
Authors: Kentroti S. , Rahman H. , Grove J. , Vernadakis A. 
Published: July 2002

AbstractThe present study was undertaken to investigate the involvement of NCAM in the neuroteratogenic effects of ethanol demonstrated by us and others. In the first experiment we examined the effect of in‐ovo ethanol exposure on expression of NCAM in various regions of the embryonic CNS throughout development. Chick embryos received ethanol (10 mg/50 μl/day) or saline (control) at days 1–3 of development (E1–E3), were sacrificed at various embryonic ages and whole brain (WB), cerebral hemispheres (CH) and cerebellum (CE) processed for SDS‐polyacrylamide gel electrophoresis. The normal developmental profile of NCAM in the chick brain exhibited the same dynamics as previously reported by others. When compared to age‐matched control brains, an increase was observed in expression of high molecular weight forms of NCAM in cerebral hemispheres between E8 and E10. These bands represented highly sialated (> 180 kDa) forms of NCAM. In fact, the NCAM band from ethanol‐treated embryos at E8 migrated at a higher molecular weight than did its control counterpart, indicating an increase in sialic acid content. In contrast, no clear change was observed in NCAM expression in cerebellum from E10 through E20 as a result of ethanol exposure. In the second experiment, we examined the involvement of NCAM in the alterations in neuronal growth patterns observed in ethanol‐exposed cultures. Neuroblast‐enriched cultures derived from three‐day‐old whole chick embryos (E3WE) were maintained on poly‐l‐lysine pre‐coated Petri dishes in DMEM + 5% fetal bovine serum with or without 50 mM ethanol. Cultures were fixed at 3, 6 or 9 DIV and co‐stained for NCAM and neurofilament (160 kDa). E3WE cultures exhibited intense NCAM immunoreactivity at 3 and 6 DIV decreasing by 9 DIV. NCAM positive structures included all neuronal perikarya, neuritic processes and growth cones. Addition of 50 mM ethanol to the medium resulted in profound alterations in growth patterns of developing neurons which continued to exhibit intense NCAM staining. Ethanol‐induced changes in the developmental profile of NCAM expression (i.e. increased sialation) in cerebral hemispheres correspond temporally with the shift in neuronal phenotype from cholinergic to catecholaminergic and GABAergic which we have reported previously. Changes in the normal pattern of cellular contact and interaction as a result of altered NCAM expression may influence establishment of neurotransmitter phenotype. Findings from this study support the view that NCAM may be involved both directly and indirectly in shaping of the CNS during development and we speculate that ethanol neuroembryotoxicity uncouples this relationship.
Definition of therapy-resistant schizophrenia and its assessment
Authors: Brenner HD , Merlo MCG 
Published: July 2002

SummaryThe treatment of nonresponsive schizophrenia poses perennial problems. The situation is made yet more complex when the great variety of patient types, their social background, family circumstances and psychosocial requirements are taken into account. The comparative lack of response to neuroleptic therapy seen in some patients, especially those with minimal structural brain changes, further complicates the problem, provoking—as such therapy may—more EPS than are normally seen in patients without more obvious physical changes in brain structure. Until recently, the treatment of nonresponsive schizophrenia has tended to involve switching from one neuroleptic (usually a “highpotent” agent) to another of different chemical structure. However, as these “typical” neuroleptics occupy D2 receptors, the rationale for using a less conventional antipsychotic, such as clozapine, is increasingly appreciated in the management of the treatment-refractory schizophrenic.
Morphological brain asymmetries in male mice withcallosal defects due to prenatal gamma irradiation
Authors: Caparelli‐Dáquer Egas M. , Schmidt Sergio L. 
Published: July 2002

AbstractWe have previously suggested a relationship between the development of the corpuscallosum and the direction of cerebral asymmetries (Schmidt and Caparelli‐Dáquer, 1989 ; Schmidt et al., 1991). Here we report a study on morphological brainasymmetries using a distinct experimental approach. At embryonic day 16, mice were exposed toa gamma source, receiving a total dose of 2 Gy. At adulthood 32 irradiated and 28 normal maleSwiss mice were evaluated for individual and populational interhemispheric asymmetries ofweight, dorsal area, and neocortical volume. All irradiated mice showed callosal defects rangingfrom total absence to a partial reduction of the midsagittal callosal area. The normal and irradiatedgroups displayed a pronounced individual asymmetry in all measurements. In contrast,populational asymmetry could be identified only in the normal group. These results are consistentwith our previous data in acallosal mutant mice and support the hypothesis that the corpuscallosum may play a role in directing interhemispheric morphological brain asymmetries.
Need for support and participation in treatment differences among subgroups of relatives to compulsorily and voluntarily admitted mentally ill individuals
Authors: Östman Margareta , Hansson Lars 
Published: July 2002

SummaryThe need for support and participation in treatment of relatives to voluntarily and compulsorily admitted patients was addressed in a study of the quality of mental health services in two Swedish county councils. The aims of the study were to investigate differences in the above aspects between subgroups of relatives, the differences between two years of investigation, 1986 and 1991, and the differences between relatives of voluntarily and compulsorily admitted patients. The relatives investigated consisted of 79 spouses, 118 parents and 31 grown-up children. The results showed that there were only minor differences between the subgroups concerning their participation in care. Grown-up children experienced significantly less need of support and received less help for this need. In 1991, relatives participated more in the care situation, were more interested in support with regard to their own life situation, and also showed more positive attitudes towards the psychiatric services than in 1986. The relatives of the voluntarily admitted patients felt more involved in the patient's treatment, whereas the relatives of those compulsorily admitted felt less involved and perceived obstacles to admission.
Feasibility and accuracy of transthoracic Doppler echocardiographic estimation of pulmonary capillary wedge pressure applying different methods
Authors: Poelzl Gerhard , Gattermeier Martin , Kratzer Horst , Zeindlhofer Eduard , Kuehn Peter 
Published: July 2002

AbstractBackground:Pulmonary wedge pressure (PWP) is an established index of cardiac function and an essential component in the management of patients with congestive heart failure and in critically ill patients.Aim:To evaluate feasibility and accuracy of non‐invasive prediction of PWP by Doppler echocardiography in daily clinical practice.Methods:Agreement was assessed between values predicted by Doppler vs. invasively measured PWP. Forty‐five consecutive patients [mean (S.D.) age 62 (10) years] with CAD (44%), DCMP (40%) and without structural heart disease (16%) were studied (EF ≤ 40% in 58% of the patients). Doppler transmitral and pulmonary venous flow velocity profiles were recorded. For binary and quantitative prediction of PWP, four different methods and five different linear equations, suggested previously in the literature, were evaluated.Results:Predictive values to identify elevated PWP were highest for pulmonary venous flow reversal exceeding the duration of forward mitral flow during atrial systole (PPV 1 and NPV 0.96). Likewise, agreement with measured PWP was highest for equations comprising both transmitral and pulmonary venous flow variables (relative mean difference 0.11, S.D. ± 4.01 mmHg for the most accurate equation). Feasibility was slightly, but not statistically, lower when pulmonary venous flow was considered vs. transmitral flow parameters alone for binary prediction (87 vs. 93%) as well as for quantitative assessment (82 vs. 93%).Conclusion:Semiquantitative prediction of elevated PWP by Doppler echocardiography is feasible as well as accurate in daily clinical practice. However, accuracy of numeric estimates is limited. Hence, invasive measurement of PWP is still necessary in certain clinical settings.
THE IMPACT OF LANGUAGE BARRIERS ON THE HEALTH CARE OF LATINOS IN THE UNITED STATES: A REVIEW OF THE LITERATURE AND GUIDELINES FOR PRACTICE
Authors: Timmins Caraway L. 
Published: July 2002

ABSTRACTAlthough Spanish was the primary language of an estimated 11% of adults in the year 2000, the U.S. health care system is largely geared toward serving English speakers. A systematic review was conducted of studies published in biomedical journals from 1990 to 2000 examining language barriers in health care for Latino populations. Aspects of the problem examined were access to health care, quality of care, and health status/health outcomes. Five (55%) of the nine studies examining access to care found a significant adverse effect of language; three (33%) found mixed or weak evidence that language affected access. Six (86%) of the seven studies evaluating quality of care found a significant detrimental effect of language barriers. Two of the three studies examining health status or outcomes found language to be a risk factor for adverse outcomes. Evidence was mixed as to the level of importance attributable to language when access to care is considered; however, non‐English‐speaking status was a marker of a population at risk for decreased access. Solid evidence showed that language barriers can adversely affect quality of care. Health care practitioners are recommended to devise an effective strategy to bridge language barriers in their setting. National laws and policies are discussed; practical guidelines and resources for providing language access in health care are provided. This article is intended to supply basic knowledge for providers and institutions in devising effective strategies for bridging the language barrier.
CERTIFIED NURSE‐MIDWIVES' KNOWLEDGE OF REIMBURSEMENT ISSUES
Authors: Ament Lynette 
Published: July 2002

ABSTRACTA recent survey examined the impact of reimbursement policies and admitting privileges on the ability of certified nurse‐midwives (CNMs) to practice and maintain an income. Many CNMs reported deficits in their knowledge about reimbursement issues. The responses to the survey indicated that service directors either do not view this information as important to their leadership role, have delegated their authority to someone else, or do not have authority over this information. Education program directors may need to examine their curricular content to determine if students are being provided adequate information to better value and understand this data.
Crystal structure of l‐rhamnose 1‐dehydrogenase involved in the nonphosphorylative pathway of l‐rhamnose metabolism in bacteria
Authors: Yoshiwara Kentaroh , Watanabe Seiya , Watanabe Yasunori 
Published: January 2021

Several microorganisms can utilize l‐rhamnose as a carbon and energy source through the nonphosphorylative metabolic pathway, in which l‐rhamnose 1‐dehydrogenase (RhaDH) catalyzes the NAD(P)+‐dependent oxidization of l‐rhamnose to l‐rhamnono‐1,4‐lactone. We herein investigated the crystal structures of RhaDH from Azotobacter vinelandii in ligand‐free, NAD+‐bound, NADP+‐bound, and l‐rhamnose‐ and NAD+‐bound forms at 1.9, 2.1, 2.4, and 1.6 Å resolution, respectively. The significant interactions with the 2′‐phosphate group of NADP+, but not the 2′‐hydroxyl group of NAD+, were consistent with a preference for NADP+ over NAD+. The C5‐OH and C6‐methyl groups of l‐rhamnose were recognized by specific residues of RhaDH through hydrogen bonds and hydrophobic contact, respectively, which contribute to the different substrate specificities from other aldose 1‐dehydrogenases in the short‐chain dehydrogenase/reductase superfamily.
Stretch, fold, and break: Intensification of emulsification of high viscosity ratio systems by fractal mixers
Authors: Hofmann Martin , Bayles Alexandra V. , Vermant Jan 
Published: January 2021

AbstractDuring emulsification process design, the bulk and interfacial rheology of the target formulation must be carefully considered. Formulations with high viscosity ratios and/or finite interfacial elasticity are particularly challenging to emulsify, as conventional drop‐breakup methods consume significant energy and provide limited control over polydispersity. Here, we develop a two‐stage process that produces monodisperse emulsions from high viscosity ratio constituents. In the first stage, a custom static mixer generates co‐flowing layers of alternate phases, and progressively thins layers until they rupture, thus forming a high‐internal phase emulsion. The interfacial properties and flow conditions that promote stable fractal multiplication are discussed. In the second stage, extensional flow elements refine the polydispersity. We demonstrate the utility of this novel process by producing remarkably monodisperse polyisobutylene‐in‐water emulsions with an energy efficiency that is orders of magnitude higher than classical emulsification methods. The moderate throughputs achieved show promise for upscaling and intensification in industrial applications.
Philipp Jolly and his 1913 “the heredity of psychosis”: Homogeneity versus heterogeneity of familial transmission and an early look at Mendelian models for manic‐depressive illness and dementia praecox
Authors: Kendler Kenneth S. , Klee Astrid 
Published: January 2021

AbstractPhilipp Jolly's 1913 extensive monograph “The Heredity of Psychoses” provides, in both his detailed literature review and new pedigree study, an extensive assessment of a key issue in the psychiatric genetics of his day: the degree to which the familial transmission of psychiatric disorders was specific (or homogeneous) versus nonspecific (or heterogeneous). Contrary to a number of earlier observations, Jolly concludes that heterogeneous transmission is rare. Multiple psychiatric disorders can occur in one family because members of a family may have elevated predispositions to more than one disorder rather than one predisposition which increases risk for a wide range of conditions. A notable exception to this, he notes, is within manic‐depressive illness (MDI), where different forms of illness run together within families. Jolly is also among the earliest investigators to evaluate simple Mendelian models for MDI and dementia praecox (DP). While his methods were primitive and contained only “eye‐ball” examinations rather than statistical modeling, Jolly demonstrated considerable conceptual sophistication in the early application of such models. He concludes that DP is likely a recessive disorder. MDI, he states, is either a recessive condition or demonstrates “gender‐based dominant heredity” where heterozygote females are affected, and heterozygote males are not.
Bubble‐Propelled Janus Gallium/Zinc Micromotors for the Active Treatment of Bacterial Infections
Authors: Lin Zhihua , Gao Changyong , Wang Daolin , He Qiang 
Published: January 2021

AbstractWe report a bubble‐propelled Janus gallium/zinc (Ga/Zn) micromotor with good biocompatibility and biodegradability for active target treatment of bacteria. The Janus Ga/Zn micromotors are fabricated by asymmetrically coating liquid metal Ga on Zn microparticles and display self‐propulsion in simulated gastroenteric acid (pH 0.5) at a speed of up to 383 μm s−1, propelled by hydrogen bubbles generated by the zinc–acid reaction. This motion of Ga/Zn micromotors is enhanced by the Ga–Zn galvanic effect. The GaIII cations produced from the degradation of Ga/Zn micromotors serve as a built‐in antibiotic agent. The movement improves the diffusion of GaIII and results in a significant increase of the antibacterial efficiency against H. pylori, compared with passive Ga microparticles. Such Ga/Zn micromotors combine the self‐propulsion, good biocompatibility and biodegradability, and Ga‐based antibacterial properties, providing a proof of concept for the active treatment of bacterial infections.
ZIF‐8 Membrane Permselectivity Modification by Manganese(II) Acetylacetonate Vapor Treatment
Authors: Hayashi Mikio , Lee Dennis T. , de Mello Matheus Dorneles , Boscoboinik J. Anibal , Tsapatsis Michael 
Published: January 2021

AbstractVapor‐phase treatment of ZIF‐8 membranes with manganese(II) acetylacetonate (Mn(acac)2) allows permselectivity tuning. Propylene/propane selectivity increases from 31 to 210 after the Mn(acac)2 treatment at 165 °C for 30 min, while selectivities increase from 14.6 to 242 for H2/CH4, from 2.9 to 38 for CO2/CH4, from 2.4 to 29 for CO2/N2, and from 2.9 to 7.5 for O2/N2, after Mn(acac)2 treatment at 175 °C for 30 min. Stable equimolar propylene/propane mixture selectivity of 165 at ambient temperature and 4 bar equimolar feed with a propylene flux of 8.3×10−4 mol m−2 s−1 is established. A control experiment excludes thermal treatment alone causing these changes. XPS analysis reveals the presence of Mn(acac)2 on the outer surface of the vapor‐treated ZIF‐8 membranes while no other changes are detectable by X‐ray diffraction and infrared spectroscopy.