bluuebunny/crossref_metadata_2025_split huggingface dataset:
Editorial - RPER v4n2
Authors: Barbosa Ribeiro Maria Isabel 
Published: December 2021

Enfermagem em geral, Enfermagem de Reabilitação em particular e a Sustentabilidade Ambiental

Sustentabilidade Ambiental é um tema que nos inquieta todos os dias. Será que efetivamente estamos a ter um comportamento adequado e mesmo nos pequenos gestos esta preocupação está presente?
Temos todos que fazer um grande esforço para mudar hábitos, com foco particular nas profissões da saúde e nas suas “pegadas ambientais”.
Analisando nesta vertente o quotidiano dos enfermeiros em geral, percebemos que há muito espaço de melhoria para evitar desastres ecológicos.
Quantos resíduos fabricamos diariamente? Podemos mudar algumas praticas? Fazemos uma separação correcta de resíduos e procuramos reduzir os seus volumes? Estas são algumas das questões que podem fazer diferença no impacto ambiental.
Os Enfermeiros de Reabilitação pela essência da sua pratica,são profissionais que estão próximos de conceitos como reutilizar, reinventar, restaurar, reparar e sem duvida com recursos naturais pouco poluentes.
Utilizam as mãos e a imaginação. Aproveitam e por vezes inventam instrumentos simples, de baixa pegada ambiental, para devolver a autonomia ao cidadão.
São profissionais que na essência da sua atividade avaliam e planeiam de acordo com o potencial do doente, rentabilizando os recursos com o foco na sua autonomia, apelando a uma vida saudável, com mais qualidade e mais sustentável.
Temos todos metas a cumprir até 2030 para garantir um mundo melhor e garantir um futuro com qualidade para os nossos descendentes. Como profissionais de saúde, temos obrigação de introduzir estes conceitos na nossa dinâmica diária sendo parte da qualidade assistencial. O ensino tem um papel relevante nesta matéria. As questões ecológicas devem fazer parte integrante dos conteúdos programáticos académicos bem como da formação em contexto profissional.
Deixo-vos aqui o desafio para investigarem como melhorar a nossa pratica na vertente ecológica, fazendo melhor com “consumo consciente”.
Não tenho dúvidas que nós, Enfermeiros de Reabilitação temos potencial não só para reabilitar a pessoa mas também o seu ambiente numa missão exemplar para a sociedade em geral.
Fico a aguardar com a melhor expectativa, o vosso contributo sobre o modo como reinventar a prática da Enfermagem na vertente da sustentabilidade ambiental.

Festas Felizes e Ecológicas.

Abraço,

Isabel Ribeiro
Centro Hospitalar Universitário de S. João, EPE, Portugal
Hubungan Komorbid Hipertensi dengan Kematian pada Kasus Konfirmasi COVID-19 di DKI Jakarta, Maret-Agustus 2020
Authors: Wulandari Endang Widuri , Ronoatmodjo Sudarto , Salama Ngabila 
Published: December 2021

Pandemi COVID-19 berdampak pada kesehatan masyarakat dan sosial ekonomi. Sampai dengan 31 Januari 2021 dilaporkan 1.078.314 kasus COVID-19 dengan 29.998 kematian (CFR: 2,78%) dari 510 kabupaten di 34 provinsi di Indonesia dengan kasus yang tertinggi dilaporkan dari DKI Jakarta sebanyak 269.718 kasus dengan 4.267 kematian. Berdasarkan Riset Kesehatan Dasar tahun 2018 prevalensi hipertensi di DKI Jakarta 10,17 %, lebih tinggi dibandingkan prevalensi hipertensi nasional (8,36%). Penelitian ini bertujuan untuk mengetahui besarnya hubungan antara komorbid hipertensi dengan kematian COVID-19 di DKI Jakarta dengan menghitung Hazard Rasio (HR). Desain penelitian ini kohort retrospektif dengan menggunakan data sekunder dari laporan COVID-19 dinas kesehatan provinsi DKI Jakarta periode Maret-Agustus 2020 dengan kriteria inklusi kasus konfirmasi COVID-19 yang dilaporkan pada periode Maret-Agustus 2020, bertempat tinggal di DKI Jakarta dengan data variabel yang diteliti lengkap. Data dianalisis menggunakan regresi cox proporsional hazard. Hasil penelitian didapatkan bahwa kasus COVID-19 dengan komorbid hipertensi mempunyai risiko 2,2 kali mengalami kematian dibandingkan dengan kasus COVID-19 tanpa komorbid hipertensi (HR 2,2 Pv < 0,001 95% CI 1,66-3,87) setelah dikontrol variabel perancu komorbid gagal ginjal kronik, kelompok usia, gejala klinis sesak nafas, malaise dan pneumonia. Hal ini menunjukkan perlunya perhatian khusus untuk pencegahan dan penatalaksanaan kasus COVID-19 dengan komorbid hipertensi untuk menurunkan risiko kematian.
Analisis Kebijakan Pembiayaan Program Pengendalian Penyakit Tuberkulosis di Provinsi Daerah Istimewa Yogyakarta
Authors: Lustiyati Elisabeth Deta , Untari Jati 
Published: December 2021

Masalah pembiayaan TB masih menjadi kendala besar di Dinas Kesehatan Provinsi maupun Kabupaten/Kota terutama saat sumber dari pendonor semakin turun jumlahnya dan tidak menutup kemungkinan dihentikan. Tujuan penelitian ini adalah untuk mengidentifikasi permasalahan dan strategi pembiayaan program TB. Rancangan penelitian menggunakan mixed method (kuantitatif kualitatif) dengan desain studi kasus. Subjek penelitian 11 orang dari Dinas Kesehatan, BPJS Kesehatan, rumah sakit dan puskesmas. Hasil analisis didapatkan bahwa sumber utama anggaran TB di Dinas Kesehatan Provinsi berasal dari pendonor lebih dari 50% global fund. Dinas Kesehatan wajib (1) menyusun standar, mengesahkan, dan mensosialiasikan standar alur rujukan TB yang wajib dilakukan oleh pelayanan kesehatan swasta dalam rangka penegakan diagnosis TB; (2) melakukan sosialisasi tentang tanggung jawab dan batasan pelayanan kesehatan yang dibiayai oleh JKN dan pemerintah ke seluruh jajaran kesehatan dengan melibatkan pihak BPJS Kesehatan. Puskesmas dapat melakukan lobbying, negosiasi, dan advokasi ke pemerintah desa untuk sharing pembiayaan program pengendalian penyakit TB. Peran lintas sektor serta pemberdayaan masyarakat dalam bentuk Gerduda TB tetap dipertahankan. Strategi pembiayaan TB dilakukan dengan menganalisis berbagai revenue collection yang melibatkan public-private mix untuk mem-backup kegiatan yang semula dibiayai oleh pendonor sehingga tujuan prioritas kesehatan nasional dapat dicapai sesuai dengan target para pengambil kebijakan.
Analisis Penerapan Kurikulum Pendidikan Kesehatan Reproduksi Berbasis Program
Authors: Kamila Ami , Handayani Fatiah , Nurhayati Nurhayati 
Published: December 2021

Kurangnya pengetahuan remaja terkait kesehatan reproduksi masih menjadi permasalahan saat ini. Kelompok remaja seharusnya bisa disiapkan agar mampu menghadapi tantangan saat ini dan masa mendatang. Pendidikan kesehatan reproduksi yang terintegrasi dengan sistem pembelajaran di sekolah akan mampu menjangkau remaja yang diharapkan mampu untuk meningkatkan pengetahuan kesehatan reproduksi dan menghindari perilaku berisiko. Penelitian ini bertujuan untuk menganalisis rancangan dan efektivitas penerapan kurikulum kesehatan reproduksi berbasis program pada siswa SMP. Penelitian ini merupakan penelitian mixed methods dengan sequential explolatory designs untuk kualitatif dan Quasi experiment dengan one group pretest-posttest design untuk kuantitatif. Rancangan kurikulum disusun berdasarkan hasil analisis kebutuhan melalui Focus Group Discussion (FGD). Hasil FGD menunjukkan bahwa sekolah tidak memiliki rancangan pembelajaran khusus untuk pendidikan kesehatan reproduksi sebelumnya. Adapun yang sudah dilaksanakan merupakan program kesiswaan yang dikhususkan untuk siswi saja. Pendidik yang terlibat dalam program tersebut merupakan guru matematika dan biologi serta belum pernah mendapatkan pelatihan khusus terkait pembelajaran kesehatan reproduksi. Selama ini pembelajaran dilakukan dengan diskusi tanpa media gambar, sedangkan referensi yang dipakai adalah modul kesehatan reproduksi. Hasil analisa kuantitatif menunjukkan penerapan kurikulum pendidikan kesehatan reproduksi efektif dan memiliki pengaruh yang positif untuk meningkatkan pengetahuan siswa (Pv=0,000).
ПОЗИЦІЇ ЛІДЕРА У СТРУКТУРІ ДЕРЖАВНОГО УПРАВЛІННЯ
Authors: Андрієнко Микола , Гаман Петро , Гордєєв Павло , Якубов Валерій 
Published: December 2021

В сучасних умовах Україна, як незалежна держава поставила перед собою ряд завдань, в тому числі створити індивідуальну державну політику, як в цілому так і в різних сферах діяльності. Значною мірою це стосується кадрової політики, механізмів її реалізації, як універсального важеля, на основі якого держава має вплив на стан суспільного, економічного та політичного розвитку. Метою дослідження є обґрунтування сучасних підходів до позицій лідера у структурі державного управління. Важливим аспектом вирішення даної проблеми є ефективність управлінської діяльності, так як від її результативності залежить функціональна спроможність організації. Враховуючи це, необхідно побудувати комфортні, з боку суб’єкта та об’єкта управлінської діяльності умови, які задовольнять всіх учасників даного процесу та будуть відрізнятися значно вищим рівнем відповідальності до виконання соціальної функції держаного управління. Концепція розвитку лідерства є теоретичним конструктом, що містить стратегію, основні напрями, завдання та цілі вдосконалення діяльності персоналу державної служби, яка покращить якість реалізації управління державою. Визначено, що лідерство є новою якістю управління людськими ресурсами. Для розвитку професійної державної служби необхідно забезпечити якість розвитку сталої спроможності лідерства. Лідерство у державному секторі пов’язане з поєднанням навичок і компетенцій, які підтримують особистий вплив, визначення мети, стратегічне мислення, отримання максимальної віддачі від людей, навчання та самовдосконалення. Проаналізовано основні засади лідерства у структурі державного управління. Теорія лідерства за Н. Макіавеллі визначено теоретичним підгрунтям дослідження. Здійснено систематизацію теорій лідерства. охарактеризовано основні зміни, щодо управління персоналом на державному рівні після прийняття Закону України «Про державну службу», узагальнено навички лідера в рамках державного управління та виокремлено особистісні характеристики лідера при реалізації державного управління.
PENERAPAN FUZZY TSUKAMOTO UNTUK MENENTUKAN JUMLAH PRODUKSI RAKIK
Authors: Mandala Eka Praja Wiyata , Putri Dewi Eka 
Published: December 2021

Abstract: The home industry, especially in the culinary sector, has grown in recent years. Many business actors produce the same products as other business actors, so competition often occurs. One of them is the Usaha Rakik Julidar which since 25 years ago made and sold rakik. There are so many types of rakik that there are minimarkets with different business actors. This makes the rakik not sold out at the convenience store and has an effect on the amount of production. This research was conducted to assist the Usaha Rakik Julidar in predicting the amount of production using Fuzzy Tsukamoto inference method. This research creates a web-based application to help predict the amount of production by looking at incoming demand and the number of workers available. From the prediction results with Fuzzy Tsukamoto, if the demand is 125 packs and the number of workers is 35 people, then the total production to be done is 140 packs. By obtaining a clear amount of production, this application really helps Usaha Rakik Julidar in maximizing production. Keywords: fuzzy tsukamoto; prediction; production; rakik Abstrak: Industri rumah tangga khususnya di sektor kuliner banyak tumbuh dalam beberapa tahun terakhir. Banyak pelaku usaha menghasilkan produk yang sama dengan pelaku usaha lainnya, sehingga sering terjadi persaingan. Salah satunya adalah Usaha Rakik Julidar yang sejak 25 tahun yang lalu membuat dan menjual rakik. Banyak sekali jenis Rakik yang ada minimarket dengan pelaku usaha yang berbeda. Hal ini membuat rakik tidak terjual habis di minimarket dan berpengaruh pada jumlah produksi. Penelitian ini dilakukan untuk membantu Usaha Rakik Julidar dalam melakukan prediksi jumlah produksi dengan menggunakan metode inferensi fuzzy Tsukamoto. Penelitian ini membuat aplikasi berbasis web untuk membantu melakukan prediksi jumlah produksi dengan melihat permintaan yang masuk dan jumlah pekerja yang tersedia. Dari hasil prediksi dengan fuzzy Tsukamoto, jika permintaan sebanyak 125 bungkus dan jumlah tenaga kerja 35 orang, maka jumlah produksi yang harus dilakukan adalah 140 bungkus. Dengan diperolehnya jumlah produksi yang jelas, aplikasi ini sangat membantu Usaha Rakik Julidar dalam memaksimalkan produksi. Kata kunci: fuzzy tsukamoto; prediksi; produksi; rakik
Role of non-resident subpopulations of mucosal and adaptive immune systems in patients with chronic periodontitis
Authors: Mudrov V. P. , Davidova N. V. , Kazakov S. P. , Mishina T. E. 
Published: December 2021

Periodontal bacterial bioflm causes an innate and adaptive immune response of the host mucosa, leading to inﬂammation and destruction of the tissues supporting the periodontal. The progression of periodontitis depends not only on bacteria, since an inadequate immune response to microorganisms can accelerate the development of periodontitis. However, the exact mechanisms of the development of immune reactions remain unclear. Recent studies emphasize the existence of a typical innate response of resident and extravasated immune cells.Objective. To investigate the quantitative composition of non-resident subpopulations of lymphocytes in salivary ﬂuid and to study the mechanisms of interaction of the cellular link of the innate and adaptive immune system in chronic generalized periodontitis of varying severity.Materials and methods. 49 people aged 26–67 years of both sexes were examined with a diagnosis of chronic periodontitis. The comparison group consisted of 17 people aged 26–44 years with no periodontal diseases. The state of the cellular link of the adaptive and local immune system of the oral cavity was assessed by the following phenotypes: CD3–CD16+56+; CD3+CD16+56+; CD3+; CD3+HLA-DR+; CD19+, CD19+HLA-DR+; CD19+CD5+CD27–; CD19+CD5–СD 27–; CD19+СD5–CD27+.Results. The number of T-NK cells decreased with a mild degree of periodontitis and increased with a severe degree. Similarly, CD3+HLA-DR+ decreased with mild periodontitis [Me = 0.148 cells/µl] and increased with moderate [Me = 0.247 cells/µl] and severe [Me = 0.448 cells/µl]. The number of B-lymphocytes with the CD19+, CD19+CD5+, CD19+CD5–CD27+ phenotype decreased to single cells per microliter during the development of the disease.Conclusion. The imbalance of the immune system caused by pathogenic colonization of the periodontium, at different degrees of severity, is an important factor in the occurrence and development of periodontitis, in which various subsets of B cells of the adaptive immune system play a certain role, closely interacting with the cellular link of the innate mucosal immune system
Best-Compromise Control Strategy Between Mechanical Energy Expenditure and Foot Clearance for Obstacle-Crossing in Older Adults: Effects of Tai-Chi Chuan Practice
Authors: Kuo Chien-Chung , Chen Sheng-Chang , Wang Jr-Yi , Ho Tsung-Jung , Lu Tung-Wu 
Published: December 2021

Background: Obstacle-crossing increases the risk of falls in older people. This study aimed to identify the effects of long-term Tai-Chi Chuan (TCC) practice on the control strategies for obstacle-crossing in older people.Methods: A multi-objective optimal control technique with measured gait data was used to identify the control strategies adopted by 15 long-term TCC practitioners and 15 healthy controls when crossing obstacles of different heights, in terms of the best-compromise weighting sets for the conflicting objectives of minimizing energy expenditure and maximizing the toe-obstacle and heel-obstacle clearances.Results and Conclusions: The long-term TCC older practitioners adopted a best-compromise control strategy similar to those adopted by young adults, with greater weightings on the minimization of the mechanical energy expenditure and smaller weightings on foot-clearance as compared to non-TCC controls (TCC: 0.72, 0.14, 0.14; Control: 0.55, 0.225, 0.225). This strategy enabled the long-term TCC older practitioners to cross obstacles with significantly greater leading-toe clearances but with relatively less mechanical energy expenditure. With the current approach, further simulations of obstacle-crossing mechanics with a given weighting set will be useful for answering clinically relevant what-if questions, such as what abilities would be needed if the non-TCC older people were to cross obstacles using the crossing strategy of the TCC people.
The Effect of Axial Length Elongation on Corneal Biomechanical Property
Authors: Liu Guihua , Rong Hua , Zhang Ping , Xue Yu , Du Bei , Wang Biying , Hu Jiamei , Chen Zhi , Wei Ruihua 
Published: December 2021

Background: To investigate the correlation between the corneal biomechanical parameter stress-strain index (SSI) and axial length (AL) in moderately elongated eye (MEE) and severely elongated eye (SEE).Methods: This study included 117 eyes from 117 participants. Among them, 59 (50.4%) had MEE (AL&lt;26 mm) and 58 (49.6%) had SEE (AL≥26 mm). AL was measured using Lenstar LS-900, and central corneal thickness (CCT) and anterior chamber volume (ACV) were measured using Pentacam. SSI was measured via corneal visualisation Scheimpflug technology (Corvis ST). Kolmogorov-Smirnov test, Student’s t-test, and Pearson and partial correlation analyses were used for statistical analyses.Results: The mean (±SD) SSI was 1.08 ± 0.15 in the MEE group and 0.92 ± 0.13 in the SEE group (p &lt; 0.01). SSI was positively correlated with age (MEE: r = 0.326, p &lt; 0.05; SEE: r = 0.298, p &lt; 0.05) in both groups; it was negatively correlated with AL (r = −0.476, p &lt; 0.001) in the MEE group but not in the SEE group (p &gt; 0.05). CCT was negatively correlated with AL (r = −0.289, p &lt; 0.05) and ACV positively correlated with AL (r = 0.444, p &lt; 0.001) in the MEE group. Neither CCT nor ACV was correlated with AL (p &gt; 0.05) in the SEE group.Conclusion: Corneal biomechanical parameter SSI, which represents the stiffness of corneal tissue, was lower in the SEE group than in the MEE group. When analyzed separately, SSI was negatively correlated with AL in the MEE group, but not in the SEE group, which may provide insight into different ocular growth patterns between lower myopia and higher myopia.
Negatively Regulated by miR-29c-3p, MTFR1 Promotes the Progression and Glycolysis in Lung Adenocarcinoma via the AMPK/mTOR Signalling Pathway
Authors: Li Yongmeng , Liu Yanfei , Jin Kai , Dong Rui , Gao Cun , Si Libo , Feng Zitong , Zhang Huiying , Tian Hui 
Published: December 2021

Background: Lung adenocarcinoma (LUAD) is the major form of lung cancer that presents a major peril to public health. Owing to the high rates of morbidity, mortality and chemoresistance, it is necessary to develop more effective therapeutic targets of LUAD. Mitochondrial fission regulator 1 (MTFR1) affects the occurrence and development of some diseases by regulating mitochondrial dynamics and is dysregulated in LUAD. However, the functions and molecular mechanisms of MTFR1 in LUAD have not been investigated.Methods: Immunohistochemical (IHC) analysis, real-time quantitative polymerase chain reaction (RT-qPCR), bioinformatic analysis and western blot (WB) were performed to assess the expression of MTFR1 at both protein and mRNA levels. The biological functions of MTFR1 in LUAD cells were assessed based on various in vivo and in vitro experiments. The dual-luciferase reporter assay and some rescue experiments were performed to evaluate the underlying mechanism of MTFR1 in LUAD.Results: MTFR1 was upregulated in LUAD cells and tissues and correlated with dismal clinicopathologic features and a worse prognosis of patients with LUAD. Functionally, MTFR1 overexpression stimulated the proliferation, invasion, migration and glycolytic capacity and impeded the apoptosis of LUAD cells; however, opposite results were obtained when MTFR1 expression was knocked down. MTFR1, which was directly targeted by miR-29c-3p, may exert its biological functions through the AMPK/mTOR signalling pathway.Conclusion: MTFR1 promotes the progression of LUAD. Therefore, targeting MTFR1 can offer an effective therapeutic strategy for LUAD treatment.
Breathing In-Depth: A Parametrization Study on RGB-D Respiration Extraction Methods
Authors: Kempfle Jochen , Van Laerhoven Kristof 
Published: December 2021

As depth cameras have gotten smaller, more affordable, and more precise, they have also emerged as a promising sensor in ubiquitous systems, particularly for detecting objects, scenes, and persons. This article sets out to systematically evaluate how suitable depth data can be for picking up users’ respiration, from small distance changes across the torso over time. We contribute a large public dataset of depth data over time from 19 persons taken in a large variety of circumstances. On this data, we evaluate and compare different state-of-the-art methods and show that their individual performance significantly depends on a range of conditions and parameters. We investigate the influence of the observed torso region (e.g., the chest), the user posture and activity, the distance to the depth camera, the respiratory rate, the gender, and user specific peculiarities. Best results hereby are obtained from the chest whereas the abdomen is least suited for detecting the user’s breathing. In terms of accuracy and signal quality, the largest differences are observed on different user postures and activities. All methods can maintain a mean accuracy of above 92% when users are sitting, but half of the observed methods only achieve a mean accuracy of 51% while standing. When users are standing and additionally move their arms in front of their upper body, mean accuracy values between the worst and best performing methods range from 21 to 87%. Increasing the distance to the depth camera furthermore results in lower signal quality and decreased accuracy on all methods. Optimal results can be obtained at distances of 1–2 m. Different users have been found to deliver varying qualities of breathing signals. Causes range from clothing, over long hair, to movement. Other parameters have shown to play a minor role in the detection of users’ breathing.
Association Between Social Support and Medication Literacy in Chinese Patients With Coronary Heart Disease
Authors: Qiao Li , Ding Siqing , Zhong Zhuqing , Liu Xiaoqing , Lai Lin , Zheng Feng 
Published: December 2021

Background: The level of medication literacy is very important to control symptoms and improve the prognosis of patients with coronary heart disease (CHD). The positive role of social support is able to promote patient health outcomes. However, few studies have addressed the association between social support and medication literacy in patients with CHD. The purpose of this study is to investigate the status of medication literacy and social support, and confirm the association between them in patients with CHD.Methods: This cross-sectional study investigated 416 participants, and was conducted in a grade a hospital in China. Three different survey instruments were applied: The Demographic Characteristics Questionnaire, the Chinese Version of the Medication Literacy Scale, and the Social Support Rating Scale. Pearson correlation analysis and ordinal logistic regression analysis were performed to analyze data.Results: The results showed that the mean score of medication literacy among the 416 participants was 4.96 ± 4.68, 48.8% (203) participants with inadequate medication literacy. The independent determinants of medication literacy include gender, education level, course of disease, number of medicines, and subjective support in social support. The mean score of social support was 41.05 ± 6.16. The Pearson correlation analysis indicated that social support was positively correlated with medication literacy (r = 0.398, P &lt; 0.01).Conclusion: The study shows that the level of medication literacy and social support for patients with CHD are inadequate. Social support levels could have a positive effect on medication literacy of patients.