bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Features and Survival Outcome of Early-Stage Primary Pulmonary MALT Lymphoma After Surgical Treatment
Authors: Xu Ye , Zheng Min , Guo Qingkui , Wang Ning , Wang Rui 
Published: August 2021

Background: We aimed to study the clinical features and survival outcomes of patients with early-stage primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma who underwent surgery.Methods: This is a retrospective, single-center study including 32 patients with early-stage primary pulmonary MALT lymphoma. Univariate and multivariate Cox analyses were performed to select independent prognostic factors. The overall survival (OS) was analyzed by the Kaplan-Meier method and was compared with the log-rank test.Results: Among the 32 patients included, there were 16 men (50.0%) and 16 women (50.0%). The average age was 59.2 years old. Ten patients had non-specific clinical symptoms including cough, expectoration, and chest pain, and four patients had B symptoms. CT images are not specific and can be shown as peripheral, central, solid, and ground glass but more peripheral (93.8%) and solid (75.0%). In prognostic analysis, univariate analysis showed that tumor stage and size were associated with relapse-free survival (RFS) and OS [hazard ratio (HR) = 1.105, 95% CI: 1.021–1.197, P = 0.011; HR = 1.211, 95% CI: 1.158–1.968, P = 0.003, respectively]. It seems to indicate that higher stage and larger size indicate a worse prognosis, but we could not find statistically significant predictors in multivariate analysis. Sublobectomy was performed in 21 (65.6) cases, lobectomy was performed in the other 11 (34.4) cases, both of them can achieve good prognosis (5-year RFS and OS are both 100%), and there is no significant difference between them.Conclusions: The clinical manifestation of early-stage primary pulmonary MALT lymphoma is not significantly specific, and surgical resection is an effective treatment.
Impervious Surfaces Mapping at City Scale by Fusion of Radar and Optical Data through a Random Forest Classifier
Authors: Shrestha Binita , Stephen Haroon , Ahmad Sajjad 
Published: August 2021

Urbanization increases the amount of impervious surfaces, making accurate information on spatial and temporal expansion trends essential; the challenge is to develop a cost- and labor-effective technique that is compatible with the assessment of multiple geographical locations in developing countries. Several studies have identified the potential of remote sensing and multiple source information in impervious surface quantification. Therefore, this study aims to fuse datasets from the Sentinel 1 and 2 Satellites to map the impervious surfaces of nine Pakistani cities and estimate their growth rates from 2016 to 2020 utilizing the random forest algorithm. All bands in the optical and radar images were resampled to 10 m resolution, projected to same coordinate system and geometrically aligned to stack into a single product. The models were then trained, and classifications were validated with land cover samples from Google Earth’s high-resolution images. Overall accuracies of classified maps ranged from 85% to 98% with the resultant quantities showing a strong linear relationship (R-squared value of 0.998) with the Copernicus Global Land Services data. There was up to 9% increase in accuracy and up to 12 % increase in kappa coefficient from the fused data with respect to optical alone. A McNemar test confirmed the superiority of fused data. Finally, the cities had growth rates ranging from 0.5% to 2.5%, with an average of 1.8%. The information obtained can alert urban planners and environmentalists to assess impervious surface impacts in the cities.
Atributos físicos e químicos do solo cultivado com gravioleira, sob adubação orgânica e mineral
Authors: Oliveira de Malta Altamiro , Esfrain Pereira Walter , Nóbrega Torres Mariana Neves , Oliveira de Malta Alan , Soares da Silva Edgley , Alves da Silva Samuel Inocêncio 
Published: August 2021

A gravioleira é uma espécie frutífera que vem despertando interesse dentre os fruticultores do Brasil, no entanto, existem poucas informações relativas ao manejo da adubação. Sendo assim, o objetivo deste experimento foi avaliar os atributos físicos e químicos do solo de um pomar de gravioleira em função da adubação orgânica e mineral. Foi instalado um experimento em um pomar de gravioleira com 42 meses de idade entre os meses de janeiro a setembro de 2014, na cidade Areia-PB. O delineamento experimental foi em blocos casualizados, com sete tratamentos e quatro repetições. Os tratamentos utilizados foram: T1= testemunha (sem adubação); T2= adubação mineral (NPK); T3= esterco de bovino; T4= esterco de aves; T5= adubação mineral + esterco de caprino; T6= esterco de aves + 3 kg de pó de rocha; T7= esterco de caprino. As variáveis de fertilidade e de física do solo avaliadas foram: pH, fósforo, potássio, sódio, cálcio, magnésio, alumínio, hidrogênio + alumínio, carbono, matéria orgânica, densidade e porosidade do solo. Os dados foram submetidos à análise de variância e ao o teste de Tukey. A adubação com esterco bovino influenciou positivamente os teores de potássio, sódio, carbono e matéria orgânica do solo; O esterco de aves isolado e adicionado ao pó de rocha, manteve o pH do solo numa faixa que favorece a disponibilidade de nutrientes, além de fornecer maior teor de fósforo no solo; Nenhum dos tratamentos afetou os teores de cálcio, magnésio, alumínio, hidrogênio + alumínio, além da densidade e porosidade total do solo.
Jó színvonalú hazai tejtermelő üzem gazdasági elemzése
Authors: Kovács Krisztián , Vida Viktória , Madai Hajnalka , Szűcs István 
Published: August 2021

A kutatás magában foglalja a tejtermelő üzemi adatokon alapuló – üzemgazdasági elemzését, mely által értékelhetővé válik az ágazat – jó színvonalon való működését feltételezve – a költség-jövedelem viszonyok, illetve a működési hatékonysága, valamint a feltételezett zöldmezős beruházások esetében a beruházás 10 éves időszakon értelemzett dinamikus mutatókon (NPV, IRR, PI, DPP) alapuló gazdaságossága. Mivel számos hazai tejtermelő üzem az elérhető legfejlettebb technológiával termel, így a mutatói érdemben nem maradnak el a legjobb nyugat-európai üzemekétől, ezért a vizsgált ágazat esetében ún. „jó termelési színvonalra, illetve gyakorlatra” vonatkozik az elemzés. Az elvégzett elemzés egy termelő üzemi primer adatokból létrehozott determinisztikus szimulációs modellezésen alapul mely saját adatbázist használ. A kutatás megállapításainak egy része adatokkal és kalkulációkkal alátámasztottak, míg más részük szakértői becsléseken és szakértői véleményeken alapulnak. Vizsgálataink alapján megállapítható, hogy az ún. jó termelési gyakorlatot követő modellüzem legfontosabb fajlagos naturális, ökonómiai és beruházáselemzési mutatói a tejtermelés esetén: Fajlagos éves tejhozam 11 000 kg/év; Termelési érték: 1 548,5 ezer Ft/tehén; Termelési költség: 1 312 ezer Ft/tehén; Nettó jövedelem: 236,5 ezer Ft/tehén; EBITDA: 404,6 ezer Ft/tehén; Diszkontált megtérülési idő beruházási támogatás nélkül: 11. év; Diszkontált megtérülési idő 50%-os támogatási intenzitás esetén: 6. év.JEL-kódok: Q12, Q13
Frontera e identidad, un proceso para la deconstrucción del poder:
Authors: Mugueta Miguel 
Published: August 2021

La intención de esta investigación es mostrar como algunos estudios destinados a interpretar diferentes aspectos de la problemática sobre los estudios de frontera en la denominada "Línea de Fuertes y Fortines de la Frontera Sur de la provincia de Buenos Aires" del siglo XIX, han asumido un perfil que en muchos casos reproduce los relatos de una historiografía liberal incorporando las aventuras teóricas de las investigaciones en los EEUU en el proceso de la mal denominada conquista del oeste.
Al abordar la experiencia social del pasado y la reconstrucción de una identidad nacional y latinoamericana los cuerpos conceptuales teóricos y metodológicos, al re-interpretar nuestra historia, deben asumir el compromiso académico en la integración a un Estado Nación para poder, comenzar a ser leal con los segmentos populares de un pasado que reivindica lo que no requiere la industria teórica oficial.
Existe associação entre periodontite e hipertensão arterial?
Authors: Medeiros Malcher Carlos 
Published: August 2021

Estima-se que a periodontite afete mais de 50% da população mundial e, em sua forma grave, é a sexta doença humana mais comum. Evidências clínicas apoiam que a periodontite afeta a função endotelial sistêmica e isso pode ter um impacto na hipertensão; alguns relatos sugerem possíveis efeitos diretos da bacteriemia oral relacionada à microbiota também na disfunção vascular. O objetivo do presente artigo é compreender a patogênese da hipertensão e sua associação com a periodontite, bem como os possíveis mecanismos comuns envolvidos. Foi realizada uma revisão da literatura, por meio de consulta ao MEDLINE, a fim de analisar dados recentes que sustentam que pacientes com periodontite têm maior probabilidade de apresentar hipertensão arterial. A estrutura conceitual que apoia essa hipótese é discutida. Os dados corroboram que, na presença de periodontite moderada, a probabilidade de ter hipertensão é de 22% e essa probabilidade aumenta para 49% nas formas graves. Essa condição pode contribuir potencialmente para a imunidade pró-hipertensiva de várias maneiras; além disso, pode estar associado a disfunção endotelial permanente. Assim, tornou-se evidente que a inflamação e o sistema imunológico têm um papel causal na patogênese da hipertensão, embora esse mecanismo ainda não esteja claro. Da nossa análise podemos concluir que existe uma associação entre periodontite e hipertensão e, portanto, a terapia periodontal pode ser considerada como uma ferramenta na prevenção e tratamento da hipertensão. O desafio ainda está aberto para pesquisas direcionadas ao entendimento da patogênese da hipertensão.
La ética pública en México y su relación con los derechos humanos y el derecho penal
Authors: Elizalde Castañeda Rodolfo Rafael , Aguilera García Edgar Ramón 
Published: August 2021

El objetivo de este artículo fue analizar comparativamente los códigos de ética para los servidores públicos federales que han estado vigentes en México y su relación con los derechos humanos y el derecho penal, con el fin, primero, de conocer la forma en que han evolucionado dichos códigos a partir de sus principios y valores éticos, segundo, estudiar el vínculo que guardan estos con las reformas constitucionales en derechos humanos de 2011 y en derecho penal del 18 de junio de 2008, para comprender el motivo por el que algunas organizaciones no gubernamentales (ONGs), como Human Rigth Watch (HRW), Transparencia Internacional (TI), Latinobarómetro, World Justice Proyect (WJP) y México Evalúa, siguen ubicando a México en los primeros lugares de corrupción e impunidad.
MENYUSUN KURIKULUM PAUD (PERENCANAAN PEMBELAJARAN DARI RUMAH SELAMA MENGHADAPI PANDEMI COVID-19)
Authors: AZIZAH ELISA NOVIE , Tanto Octavian Dwi , Naningtias Sulistia Arum , Rahmawati Rani Umi 
Published: August 2021

Kurikulum 2013 Pendidikan Anak Usia Dini menjadi fundamen bagi penyiapan pengembangan dan aspek struktur proses pembelajaran di jenjang Pendidikan Anak Usia Dini (PAUD). Selajutnya pada masa pandemi covid-19 ini pembelajaran dilakukan secara daring, prinsip dikeluarkannya kebijakan pendidikan di masa Pandemi Covid-19 oleh Menteri Pendidikan dan Kebudayaan (Mendikbud) adalah dengan memprioritaskan kesehatan dan keselamatan peserta didik, pendidik, tenaga kependidikan, keluarga, dan masyarakat. Tahun ajaran baru bagi pendidikan anak usia dini (PAUD), pendidikan dasar, serta pendidikan menengah di tahun ajaran 2020/2021 tetap dimulai pada bulan Juli 2020. Namun demikian, untuk daerah yang berada di zona kuning, oranye, dan merah, dilarang melakukan pembelajaran tatap muka di satuan pendidikan. Satuan pendidikan pada zona-zona tersebut tetap melanjutkan Belajar dari Rumah. Untuk menunjang sistem belajar pembelajaran (Belajar dari Rumah) saat pandemi Covid-19 maka guru harus memahami antara kurikulum yang berlaku dan kondisi dilapangan yakni dengan cara guru harus mampu membuat perencanaan pembelajaran dari Rumah (pembelajaran daring)
Tujuan dari Pengabdian Masyarakat ini yakni, untuk meningkatkan kompetensi guru Pendidikan Anak Usia Dini Kabupaten Ngawi dalam kemampuan pembuatan pengembangan perencanaaan pembelajaran dari rumah. Sedangkan metode yang dipakai dalam Pengabdian Masyarakat ini memakai metode diskusi, ceramah bervariasi, Pre-Test dan Post-Test. Selanjutnya ketercapaian pemahaman materi yang disampaikan dinilai cukup baik dengan meningkatnya hasil dari pre-test dan post-test yang telah dilakukan. Berdasarkan soal yang telah dibuat sebagai instrumen pengukuran pemahaman peserta, rata-rata peserta mendapatkan nilai 47,5 pada tes awal (pre-test) dan mendapatkan nilai 63,1 pada tes akhir (post-test), hal tersebut menunjukkan peningkatan pemahaman materi oleh peserta pasca pemberian materi.
TIPS AND TRICKS ASSISTANCE CHILDREN LEARNING FROM HOME
Authors: Wijayanti Arwendis , Narendradewi Kusumastuti  , Diah  , Miftah  
Published: August 2021

Peran orang tua sangatlah penting diperlukan dalam proses pembelajaran anak selama dirumah. Selain itu orang tua berperan penting dalam memberikan edukasi kepada anak yang masih belum bisa memahami tentang pandemi yang sedang mewabah untuk tetap berdiam diri dirumah agar tidak tertukar dan menularkan wabah pandemi COVID-19 ini.Kegiatan pengabdian ini dilakukan dalam satu kali pertemuan dengan peserta sebanyak 214 orang yang terdiri dari mahasiswa PG PAUD, guru, orang tua dan umum. Kegiatan pengabdian dilaksanakan dalam bentuk webinar melalui aplikasi zoom meeting. Diharapkan kegiatan pengabdian kepada masyarakat ini mampu meningkatkan pemahaman dan pengetahuan para orang tua, guru dan mahasiswa dalam menerapkan tips dan trik pendampingan anak belajar dari rumah di saat pandemi COVID-19 saat ini.
Re-description of the assassin bug species Pygolampis striata Miller, 1940 with new distributional records from Japan and Indonesia (Heteroptera, Reduviidae, Stenopodainae)
Authors: Okuda Kyosuke 
Published: August 2021

Pygolampis striata Miller, 1940 was previously described, based on a single male specimen. However, there are no records of the species since then. The females and nymphs were not described and knowledge about their habitat is insufficient.
This is the first record of the assassin bug Pygolampis striata Miller, 1940 from Japan and Indonesia. Here, this species has been re-described and, for the first time, the female has been described. The species was collected from the surfaces of dried Poaceae grasslands using the "Gasa-Gasa collecting method".
René Worms récidiviste
Authors: Chenu Alain 
Published: August 2021

En lettres puis en sciences, René Worms a peiné à obtenir un doctorat, ne réussissant que lors d’une seconde tentative. Sa ténacité n’a pas été récompensée : en 1912 le grade de docteur lui a été attribué avec des réserves telles qu’il ne lui ouvrait aucune nouvelle perspective de carrière. Pour ce collectionneur de diplômes, la soutenance de sciences était une amère victoire.
STAT5 Represses a STAT3-Independent Th17-like Program during Th9 Cell Differentiation
Authors: Canaria D Alejandro , Yan Bingyu , Clare Maia G , Zhang Zonghao , Taylor Grace A , Boone David L , Kazemian Majid , Olson Matthew R 
Published: August 2021

Abstract
IL-9–producing Th cells, termed Th9 cells, contribute to immunity against parasites and cancers but have detrimental roles in allergic disease and colitis. Th9 cells differentiate in response to IL-4 and TGF-β, but these signals are insufficient to drive Th9 differentiation in the absence of IL-2. IL-2–induced STAT5 activation is required for chromatin accessibility within Il9 enhancer and promoter regions and directly transactivates the Il9 locus. STAT5 also suppresses gene expression during Th9 cell development, but these roles are less well defined. In this study, we demonstrate that human allergy-associated Th9 cells exhibited a signature of STAT5-mediated gene repression that is associated with the silencing of a Th17-like transcriptional signature. In murine Th9 cell differentiation, blockade of IL-2/STAT5 signaling induced the expression of IL-17 and the Th17-associated transcription factor Rorγt. However, IL-2–deprived Th9 cells did not exhibit a significant Th17- or STAT3-associated transcriptional signature. Consistent with these observations, differentiation of IL-17–producing cells under these conditions was STAT3-independent but did require Rorγt and BATF. Furthermore, ectopic expression of Rorγt and BATF partially rescued IL-17 production in STAT3-deficient Th17 cells, highlighting the importance of these factors in this process. Although STAT3 was not required for the differentiation of IL-17–producing cells under IL-2–deprived Th9 conditions, their prolonged survival was STAT3-dependent, potentially explaining why STAT3-independent IL-17 production is not commonly observed in vivo. Together, our data suggest that IL-2/STAT5 signaling plays an important role in controlling the balance of a Th9 versus a Th17-like differentiation program in vitro and in allergic disease.
Oral health related quality of life among HIV positive patients attending two HIV outpatient clinics in Nigeria - a cross sectional study
Authors: Adesola Umeizudike Kehinde , Bamidele Osagbemiro Babatope , Oluwayemisi Daramola Opeyemi , Adenike Adeyemo Titilope 
Published: August 2021

Background: The human immunodeficiency virus infection remains a devastating disease of public health importance.
Objectives: To assess the association between oral health and quality of life and the factors affecting the oral health related quality of life among HIV positive patients in Nigeria.
Methods: This was a cross sectional study of HIV positive patients attending two HIV outpatient clinics in Nigeria. Impact of oral health on quality of life was assessed using the OHIP-14. Oral health status was assessed by the DMFT and Simpli- fied OHI indices. Level of significance was set at p< 0.05.
Results: Three hundred and fifty-two patients were seen, 64.2% being females. Prevalence of impact was 8.5%; and the mean OHIP scores was 8.05±9.54. Highest impact was “painful aching” 67(19.1%) with the domain of physical pain scoring the highest mean impact of 2.32. Most patients (88.6%) were on HAART. Following logistic regression, after controlling for potential confounders, independent factors associated with poor OHRQoL were perceived need for dental treatment, HAART use, and higher DMFT (p<0.05).
Conclusion: The domain of physical pain had the highest impact, while perceived need for dental treatment, HAART use and higher caries index were contributory to poor OHRQoL.
Keywords: HIV infection; Oral health; OHRQoL.
Prevalence and factors associated with self medication with antibiotics among University students in Moshi Kilimanjaro Tanzania
Authors: Baltazary Chuwa Bernard , Abraham Njau Linna , Ivo Msigwa Kaizali , Shao Elichilia 
Published: August 2021

Background: Self medication is a common practice of using medicines without a medical supervision by the people them- selves. Self medication is likely to happen when people feel unwell, it is worse in the population with poor helth seeking be- havior. Therefore it is important to assess the prevalence and factors associated with self medication with antibiotics among University students in Moshi, Kilimanjaro Tanzania.
Methods: A cross sectional study was conducted from April-August 2019 at two Universities in Moshi, including one med- ical and one non medical. The study population were undergraduate students aged 18 and above, A self-filled questionnaire was used for data collection and data analyzed using the SPSS version 16 and association was tested using chi square.
Results: Out 374 students enrolled 187 from each University, 126 were female and 248 were male with age ranging from 19 to 35 years with mean age of 23.91 years. The prevalence of self medication with antibiotics was 57% and the most com- mon used antibiotics was amoxicillin with prevalence of 32.08%. The common reported symptoms/diseases were headache (31.02%) followed by malaria and coughing with prevalence of 15.24% and 10.96% respectively. The commonest reasons of self medication reported to be emergency illness (38.77%) and delaying of hospital services (24.33%). The commonest effects reported among respondents which practiced self medication with antibiotics were worsening of the condition that they were suffering in (4.55%) and body rashes (2.67).There was no significant difference between self medication practices among medical and non medical students(p = 0.676).
Conclusion: The prevalence of self medication with antibiotics was high among University students and there is no signif- icant difference in both medical and non medical students. The most feared outcome on self medication with antibiotics is antibiotic drug resistance which leads to treatment failure along with high financial costs and increase mortality rate following microbial infections.
Keywords: Self-medication; antibiotics; University students; Moshi; Tanzania.
The role of body temperature on respiratory rate in children with acute respiratory infections
Authors: Ozdemır Beril , Songül Yalçın Sıddıka 
Published: August 2021

Background: The World Health Organization (WHO) recommends the use of tachypnea as a proxy to the diagnosis of pneumonia.
Objective: The purpose of this study was to examine the relationship between body temperature alterations and respiratory rate (RR) difference (RRD) in children with acute respiratory infections(ARI).
Methods:This cross-sectional study included 297 children with age 2-60 months who presented with cough and fever at the pediatric emergency and outpatient clinics in the Department of Pediatrics, Baskent University Hospital, from January 2016 through June 2018. Each parent completed a structured questionnaire to collect background data. Weight and height were taken. Body temperature, respiratory rate, presence of the chest indrawing, rales, wheezing and laryngeal stridor were also recorded. RRD was defined as the differences in RR at admission and after 3 days of treatment.
Results: Both respiratory rate and RRD were moderately correlated with body temperature (r=0.71, p<0.001 and r=0.65, p<0.001; respectively). For every 1°C increase in temperature, RRD increased by 5.7/minutes in overall, 7.2/minute in the patients under 12 months of age, 6.4/minute in the female. The relationship between body temperature and RRD wasn’t statistically significant in patients with rhonchi, chest indrawing, and low oxygen saturation.
Conclusion: Respiratory rate should be evaluated according to the degree of body temperature in children with ARI. How- ever, the interaction between body temperature and respiratory rate could not be observed in cases with rhonchi and severe pneumonia.
Keywords: Fever; tachypnea; pneumonia; respiratory rate difference; children.