bluuebunny/crossref_metadata_2025_split huggingface dataset:
A new perspective and assessment measure for common dissociative experiences: ‘Felt Sense of Anomaly’
Authors: Černis Emma , Beierl Esther , Molodynski Andrew , Ehlers Anke , Freeman Daniel 
Published: February 2021

BackgroundDissociative experiences occur across a range of mental health disorders. However, the term ‘dissociation’ has long been argued to lack conceptual clarity and may describe several distinct phenomena. We therefore aimed to conceptualise and empirically establish a discrete subset of dissociative experiences and develop a corresponding assessment measure.MethodsFirst, a systematic review of existing measures was carried out to identify themes across dissociative experiences. A theme of ‘Felt Sense of Anomaly’ (FSA) emerged. Second, assessment items were generated based on this construct and a measure developed using exploratory (EFA) and confirmatory (CFA) factor analyses of 8861 responses to an online self-report survey. Finally, the resulting measure was validated via CFA with data from 1031 patients with psychosis.Results‘Felt sense of anomaly’ (FSA) was identified as common to many dissociative experiences, affecting several domains (e.g. body) and taking different forms (‘types’; e.g. unfamiliarity). Items for a novel measure were therefore systematically generated using a conceptual framework whereby each item represented a type-by-domain interaction (e.g. ‘my body feels unfamiliar’). Factor analysis of online responses found that FSA-dissociation manifested in seven ways: anomalous experiences of the self, body, and emotion, and altered senses of familiarity, connection, agency, and reality (Χ2(553) = 4989.435, p<0.001, CFI = 0.929, TLI = 0.924, RMSEA = 0.052, SRMR = 0.047). Additionally, a single-factor ‘global FSA’ scale was produced (Χ2(9) = 312.350, p<0.001, CFI = 0.970, TLI = 0.950, RMSEA = 0.107, SRMR = 0.021). Model fit was adequate in the clinical (psychosis) group (Χ2(553) = 1623.641, p<0.001, CFI = 0.927, TLI = 0.921, RMSEA = 0.043, SRMR = 0.043). The scale had good convergent validity with a widely used dissociation scale (DES-II) (non-clinical: r = 0.802), excellent internal reliability (non-clinical: Cronbach’s alpha = 0.98; clinical: Cronbach’s alpha = 0.97), and excellent test-retest reliability (non-clinical: ICC = 0.92). Further, in non-clinical respondents scoring highly on a PTSD measure, CFA confirmed adequate model fit (Χ2(553) = 4758.673, CFI = 0.913, TLI = 0.906, RMSEA = 0.052, SRMR = 0.054).ConclusionsThe Černis Felt Sense of Anomaly (ČEFSA) scale is a novel measure of a subset of dissociative experiences that share a core feature of FSA. It is psychometrically robust in both non-clinical and psychosis groups.
A RELEVÂNCIA DO PORTAL BASE, À LUZ DOS PRINCÍPIOS FUNDAMENTAIS DA CONTRATAÇÃO PÚBLICA E DO PROCEDIMENTO DE FORMAÇÃO DOS CONTRATOS PÚBLICOS EM PORTUGAL
Authors: Anjos Azevedo Patrícia , Rua Carneiro Davide 
Published: February 2021

Resumo
Na formação e execução dos contratos públicos devem ser respeitados os princípios da legalidade, prossecução do interesse público, imparcialidade, proporcionalidade, boa-fé, tutela da confiança, sustentabilidade e responsabilidade, concorrência, publicidade e transparência, igualdade de tratamento e não-discriminação. O procedimento de formação de contratos constitui a sucessão ordenada de atos que concorrem para a formação, a conclusão e a produção de uma plena eficácia jurídica de um contrato público. O legislador define os momentos que constituem a tramitação do procedimento, numa lógica de transparência, garantindo a imparcialidade e a igualdade de tratamento e de acesso ao procedimento e a adequação procedimental.
O objetivo principal do portal Base é divulgar informação sobre os contratos públicos celebrados em Portugal sujeitos ao regime do Código dos Contratos Públicos. Para dar cumprimento a este objetivo, o portal constitui-se como uma ferramenta tecnológica que centraliza, num espaço virtual, informações referentes à formação e execução dos contratos públicos.
Palavras-Chave: Portal Base; princípios; contratação pública; procedimento; contratos públicos
A Prevention Program for Insomnia in At-risk Adolescents: A Randomized Controlled Study
Authors: Chan Ngan Yin , Li Shirley Xin , Zhang Jihui , Lam Siu Ping , Kwok Amy Pui Ling , Yu Mandy Wai Man , Chan Joey Wing Yan , Li Albert Martin , Morin Charles M. , Wing Yun Kwok 
Published: February 2021

OBJECTIVES:
To prevent the future development of insomnia in at-risk adolescents.

METHODS:
A randomized controlled trial comparing 4 weekly insomnia prevention program with a nonactive control group. Subjects were assessed at baseline, postintervention, and 6 and 12 months after intervention. Assessors were blinded to the randomization. Analyses were conducted on the basis of the intention-to-treat principles.

RESULTS:
A total of 242 adolescents with family history of insomnia and subthreshold insomnia symptoms were randomly assigned to an intervention group (n = 121; mean age = 14.7 ± 1.8; female: 51.2%) or control group (n = 121; mean age = 15.0 ± 1.7; female: 62.0%). There was a lower incidence rate of insomnia disorder (both acute and chronic) in the intervention group compared with the control group (5.8% vs 20.7%; P = .002; number needed to treat = 6.7; hazard ratio = 0.29; 95% confidence interval: 0.12–0.66; P = .003) over the 12-month follow-up. The intervention group had decreased insomnia symptoms (P = .03) and reduced vulnerability to stress-related insomnia (P = .03) at postintervention and throughout the 12-month follow-up. Decreased daytime sleepiness (P = .04), better sleep hygiene practices (P = .02), and increased total sleep time (P = .05) were observed at postintervention. The intervention group also reported fewer depressive symptoms at 12-month follow-up (P = .02) compared with the control group.

CONCLUSIONS:
A brief cognitive behavioral program is effective in preventing the onset of insomnia and improving the vulnerability factors and functioning outcomes.
Characterization of pregnant women who gave birth in 2016 at the Hospital de La Samaritana, Bogotá D.C., Colombia
Authors: Cruz Edwin Alfonso , García-Perlaza Carlos , Sánchez-Acosta Karen , Herrera-Aranguren Lorena , Davila-Romero Viviana , Martínez-Herrera Yeraldine 
Published: February 2021

Introduction: Maternal mortality and severe maternal morbidity are serious public health problems, so it is essential to work on the identification, recognition and situation analysis of patients treated at high-risk pregnancy centers. Objectives: To characterize the pregnant women treated at the Hospital Universitario de la Samaritana (HUS), Bogotá, Colombia, from a demographic, social and clinical point of view in order to identify common factors that may be intervened and, thus, avoid adverse outcomes. Materials and methods: Cross-sectional study. 785 medical records of patients with a gestational age >24 weeks treated at the HUS in 2016 were analyzed. Sociodemographic data were collected, as well as data on the following variables: history of diseases, antenatal care, biopsychosocial risk, and obstetric outcomes. A univariate analysis was performed for each variable; measures of central tendency and dispersion and absolute and relative frequencies were calculated for quantitative and qualitative variables, respectively. Maternal health indicators were also calculated. Results: 47.51% of the pregnant women had a low educational level, 34.39% were single mothers, 32.10% had a previous comorbidity, and 5.85% had insufficient antenatal care. The proportion of preterm births was 23.6 (95%CI: 20.63%-26.69%), the severe maternal morbidity ratio was 157.96/1 000 live births, and the maternal mortality rate was 246/100 000 live births. Conclusions: Pregnant women treated at the HUS are mainly young women from areas where the health system is not easily accessible, and who have insufficient antenatal care and a low schooling level. This population has a high rate of severe maternal morbidity and maternal mortality compared to the national reference value, so they would benefit from educational interventions or risk approaches that prioritize these factors in order to prevent adverse maternal outcomes.
Assessment for learning in health sciences. An innovative pedagogical process
Authors: Beltrán-Véliz Juan Carlos , Tereucán-Angulo Julio César , Salazar-Ascencio José , Alarcón-Muñoz Ana María 
Published: February 2021

Evaluation is a critical component of teaching because it promotes effective learning, which is why it must be done correctly. In health sciences, evaluation is reductionist and technical in nature, as it focuses on summative assessments by checking the extent to which a student achieves the intended objectives and verifying said achievement, as well as on the results obtained at the end of an academic year, which translates into a grade.
Fare well to Nova Scotia? Public health investments remain chronically underfunded
Authors: Caldwell Hilary A. T. , Scruton Sarah , Fierlbeck Katherine , Hajizadeh Mohammad , Dave Shivani , Sim S. Meaghan , Kirk Sara F. L. 
Published: February 2021

AbstractInspired by Fiset-Laniel et al.’s (2020) article entitled “Public health investments: neglect or wilful omission? Historical trends in Quebec and implications for Canada”, we assessed public health investments since the establishment of the Nova Scotia provincial health authority in 2015. We analyzed Nova Scotia Department of Health and Wellness budgets from 2015−2016 to 2019–2020 and observed that less than 1% of funding was budgeted for public health annually, an amount well below the recommendation that 5–6% of healthcare funding be spent on public health. Healthcare spending has increased annually since 2015–2016, but proportions of funding to different programs and services have remained static. Specifically, we did not observe a change in investment in public health over time, suggesting that while the government does not necessarily spend too much or too little on healthcare, it spends far too little on public health. This chronic under-funding is problematic given the high rates of non-communicable diseases in Nova Scotia and health inequities experienced within the population. The 2020 COVID-19 pandemic has highlighted the importance of public health work, and the need for a pandemic recovery plan that prioritizes investment in all areas of public health in Nova Scotia.
The Finnish National Seismic Network: Toward Fully Automated Analysis of Low-Magnitude Seismic Events
Authors: Veikkolainen Toni , Kortström Jari , Vuorinen Tommi , Salmenperä Ilmo , Luhta Tuija , Mäntyniemi Päivi , Hillers Gregor , Tiira Timo 
Published: February 2021

Abstract
We present an overview of the seismic networks, products, and services in Finland, northern Europe, and the challenges and opportunities associated with the unique combination of prevailing crystalline bedrock, low natural intraplate seismic background activity, and a high level of anthropogenic seismicity. We introduce national and local seismic networks, explain the databases, analysis tools, and data management concepts, outline the Finnish macroseismic service, and showcase data from the 2017 M 3.3 Liminka earthquake in Ostrobothnia, Finland.
Serum thyroglobulin level in newly detected thyrotoxicosis and its role in differential diagnosis of thyrotoxicosis
Authors: Faruque Mohammad Omar , Kamrul-Hasan A. B. M. , Kabir M. Ahamedul , Nasim Rehnuma , Alam Mohammad Jahangir , Selim Shahjada , Hasanat Muhammad Abul , Uddin M. Farid 
Published: February 2021

Background: Elevated serum thyroglobulin (Tg) level is commonly observed in various forms of thyrotoxicosis; the levels vary according to different etiologies. This study aimed at identifying the value of serum Tg level in the differential diagnosis of common etiologies of thyrotoxicosis. Methods: This cross-sectional study was conducted at the endocrine outpatient department of a tertiary hospital in Bangladesh from March 2015 to May 2017. In this study, 200 subjects with newly detected untreated thyrotoxicosis were evaluated. Serum Tg was assayed by chemiluminescent immunometric assay. Results: Serum Tg level was raised in 48% of subjects. Subjects aged ≥40 years, and those having a family history of thyroid disorders had relatively higher thyroglobulin levels. The frequency of subjects with an elevated Tg was highest in subacute thyroiditis (89.5%) followed by toxic nodular goiter (77.3%) and Graves’ disease (32.9%); the difference in the frequencies was statistically significant (p<0.001). Median Tg was highest in the subjects with subacute thyroiditis (132.6 ng/ml) followed by toxic nodular goiter (99.55 ng/ml); those with Graves’ disease had the lowest Tg level (12.5 ng/ml); the differences in median Tg levels across the three groups were also statistically significant (p<0.001). Conclusions: Serum thyroglobulin level may be useful for the etiological diagnosis of thyrotoxicosis.
Normal anatomical variations of tibial plateau geometry in Indian population: a magnetic resonance image-based study
Authors: Ghosh Gopal , Roy Shabarna 
Published: February 2021

<p><strong>Background:</strong> Geometry of tibial plateau characterized by its medial tibial plateau slope (MTS), lateral tibial plateau slope (LTS), depth of concavity of medial tibial plateau (CMT), convexity of lateral tibial plateau on sagittal section and coronal tibial plateau slope (CTS) on coronal section of tibia.</p><p><strong>Methods:</strong> 500 subjects (male-250, female-250) were included in the study. Various tibial slopes of each subject were measured using magnetic resonance image (MRI) of knee joint. Data was analysed using appropriate statistical analysis.</p><p><strong>Results:</strong> When considering male and female one group (total population) mean (±SD) of MTS, LTS, CMT, CTS were 7.73±3.20<sup>0</sup>, 4.68±2.75<sup>0</sup>, 2.56±0.56 mm and 2.61±2.15<sup>0</sup> respectively. In male population mean (±SD) of MTS, LTS, CMT, CTS were 6.94±3.2<sup>0</sup>, 3.77±1.85<sup>0</sup>, 2.7±0.55 mm, 3.06±2.39<sup>0 </sup>respectively. In female population population mean (±SD) of MTS, LTS, CMT, CTS were 9.28±2.65<sup>0</sup>, 6.45±3.36<sup>0</sup>, 2.28±0.48 mm, 1.75±1.24<sup>0</sup> respectively. Over all MTS and LTS was poorly correlated (r=0.43). Female had significant steeper MTS (p=0.013) and LTS (p=0.001) but had less CTS (p=0.04) and shallow CMT (p=0.012) compared to male.</p><p><strong>Conclusions: </strong>Knowledge of this study could be used in different operative orthopaedic procedures (like knee arthroplasty, high tibial osteotomy, tibial plateau fracture fixation), non-contact ACL injury risk assessment.</p><p> </p>
Arthroscopic remplissage: a valuable adjunct to arthroscopic Bankart’s repair in shoulder instability
Authors: Upadhyay Gunjan , Gupta Gaurav 
Published: February 2021

<p class="abstract">Current study present results of arthroscopic shoulder stabilisation surgery. 46 consecutive patients with recurrent anterior shoulder dislocations and less than 25% Glenoid bone loss were treated with arthroscopic surgery in 2017-2020. Arthroscopic repair of Bankart’s lesion with capsular shift was performed in each. In 8 patients, where the Hill sach’s lesion was “off track” or “engaging”, arthroscopic remplissage was performed along with arthroscopic Bankart’s repair. There was no recurrence of shoulder instability after a mean follow up of 1 year. This included the non-engaging Hill sach’s group (treated with Bankart’s repair) as well as the engaging or off track Hill sach’s group (treated with Bankart’s repair and remplissage). All patients went on to obtain full forward flexion, full abduction and internal rotation. The Bankart’s and remplissage group had a mean of 8 degrees restriction of external rotation. SST scores and oxford scores had improved considerably on follow up in both groups Arthroscopic shoulder surgery provides a safe and reliable option in the management of recurrent shoulder dislocations. Arthroscopic remplissage is a useful adjunct to Bankart’s repair when treating the difficult problem of a large engaging Hill Sachs lesion.</p><p class="abstract"> </p>
Ipsilateral fractures of both the proximal and distal humerus; the ‘floating arm injury’ in children
Authors: Gogoi Paragjyoti , Das Aditi , Dhar Arijit , Roy Rajdeep 
Published: February 2021

<p>Proximal humerus fractures are usually associated with other injuries in and around the shoulder joint like clavicle fracture, acromion process fracture, coracoid process fracture, and dislocation of the shoulder joint or acromion-clavicular joint. Similarly, distal humerus fractures are normally associated with fractures of olecranon, radial head or dislocation of the elbow joint itself. However, simultaneous fracture of both the ends of humerus is rarely encountered. Literature search does reveal only a few cases of such type. This variety is also termed as floating arm. We are presenting here two cases of fracture of both the proximal and distal end of same humerus following fall from height, one of which the proximal humeral fracture was Gustillo-Anderson type II open fracture. The patient was managed by wound debridement and open reduction and fixation of the proximal fracture followed by closed manipulation and K wire fixation of the distal fracture. The second case was also managed by closed reduction and K wire fixation of both the fractures. </p>
Evaluación de la calidad de los servicios de cuidados paliativos domiciliarios: revisión de la literatura
Authors: Mejia Yahel Tatiana , Carlier Salcedo Amine Yulie , Vargas Martínez Claudia Marcela , Lopez Posada Karen Johanna , Fuentes Bermúdez Genny Paola 
Published: February 2021

Introducción: La calidad de los servicios de salud se mide con indicadores que permiten encontrar oportunidades de mejora, datos clínicos y no clínicos de relevancia, información epidemiológica y calidad percibida del servicio brindado. Los cuidados paliativos pueden ofrecerse en distintas modalidades, siendo los cuidados domiciliarios una ruta novedosa que permite el cuidado del paciente lejos del intervencionismo hospitalario; los indicadores que evalúan la calidad de esta modalidad varían respecto a los servicios intramurales. Objetivo: describir los indicadores de calidad en salud utilizados para evaluar los servicios de cuidados paliativos domiciliarios según la literatura consultada. Método: revisión sistemática de la literatura científica disponible sobre los indicadores de calidad en salud para los cuidados paliativos domiciliarios. Para valorar la calidad metodológica se usó la lista CASPe. Resultados: se encontraron 47 indicadores que evalúan la calidad de los servicios de atención domiciliaria paliativa, siendo los indicadores de resultados los que tuvieron mayor presencia. Dentro de los indicadores se midieron diversos aspectos de los cuidados paliativos como manejo de síntomas, visitas domiciliarias por personal especializado, lugar de muerte elegido, eventos relacionados con la seguridad del paciente y disponibilidad de medicamentos. Conclusiones: La medición del lugar de fallecimiento y la presencia de síntomas aun con un tratamiento farmacológico establecido fueron dos de los indicadores más encontrados. Se observó una medición al personal médico y enfermero superior al resto de profesionales que conforman el equipo multidisciplinario de cuidados paliativos, se encontraron algunos indicadores específicos para pacientes con patologías oncológicas.
Crenças e atitudes linguísticas na variação da vogal média posterior /o/ > [u] em posição tônica no português falado em Cametá-PA
Authors: Gaia Andreza Prazeres , Gomes Mariane Daysa de Castro , Costa Furtado Raquel Maria da Silva 
Published: February 2021

<p class="Tccfolhanatureza">estudos sociolinguísticos de caráter quanti-qualitativo têm evidenciado forte tendência de apagamento do alteamento da vogal média posterior /o/, marca de identidade dos cametaenses, em posição tônica (COSTA 2004; RODRIGUES 2005; GAIA, GOMES e FURTADO, 2019); e o fator escolaridade é apontado em tais estudos como condicionante da manutenção de /o/ tônico, o que aparentemente indica existência de estigma associado ao uso de [buka], [kuku], [vuvu]. Portanto, a fim de verificar se o comportamento linguístico dos cametaenses de manutenção da tônica é decorrente do estigma que recai sobre o alteamento de /o/ &gt; [u] tônico, consequentemente das crenças e atitudes acerca desse fenômeno objetivou-se realizar um estudo para analisar por meio de testes de atitudes e avaliação, se o fenômeno de alteamento da vogal posterior em posição tônica é rotulado de forma positiva ou negativa na comunidade cametaense, e se essa rotulação encontra-se no nível da consciência de seus falantes. Para isso, tomou como base de análise teórica, os pressupostos teórico-metodológicos da Teoria da Variação Linguística/ Sociolinguística Quantita­tiva, e os estudos sobre <em>crenças e atitudes linguísticas</em>, advindos principalmente da Psicologia Social baseada em Lambert e Lambert (1996). O <em>corpus </em>para análise foi oriundo de <strong>24</strong> (vinte e quatro) sujeitos participantes na faixa etária de 15 a 29 anos e 30 a 45 anos, estratificados por sexo/gênero (masculino <strong>12</strong> e feminino<strong> 12</strong>); nível de escolaridade (<strong>08</strong> com nível fundamental, <strong>08</strong> com nível médio e <strong>08</strong> com nível superior) e procedências (<strong>12</strong> cametaenses <strong>12 </strong>não cametaenses). Os resultados obtidos por meio da amostra esboçam atitudes negativas dos informantes diante do fenômeno investigado, freando dessa forma o uso da vogal média posterior de forma alteada na posição tônica. Portanto, por meio dos resultados constatou-se à identidade e o preconceito linguístico do falante diante da língua falada de sua região.</p>
Methylation of TGM-3 Promoter and Its Association with Oral Squamous Cell Carcinoma (OSCC)
Authors: Shojaeian Sorour , Moazeni-Roodi Abdolkarim , Allameh Abdolamir , Garajei Ata , Kazemnejad Anoshirvan , Kabir Kourosh , Zarnani Amir-Hassan 
Published: February 2021

Background: Oral Squamous Cell Carcinoma (OSCC) is among the ten most common cancers worldwide. Hypermethylation of CpG sites in the promoter region and subse-quent down-regulation of a tumor suppressor gene, TGM-3 has been proposed to be linked to different types of human cancers including OSCC. In this study, methylation sta-tus of CpG sites in the promoter region of TGM-3 has been evaluated in a cohort of pa-tients with OSCC compared to normal controls.
Methods: Forty fresh tissue samples were obtained from newly diagnosed OSCC patients and normal individuals referred to dentistry clinic for tooth extraction. DNA was extract-ed, bisulfite conversion was performed and it was subjected to PCR using bisulfite-sequencing PCR (BSP) primers. Prepared samples were sequenced on a DNA analyzer with both forward and reverse primers of the region of interest. The peak height values of cytosine and thymine were calculated and methylation levels for each CpG site within the DNA sequence was quantified.
Results: Quantitative DNA methylation analyses in CpG islands revealed that it was sig-nificantly higher in OSCC patients compared to controls. DNA methylation at CpG1/CpG3/CpG5 (p=0.004-0.01) and CpG1/CpG3 (p=0.001-0.019) sites was associated with tumor stage and grade, respectively. Male OSCC patients had higher methylation rate at CpG3 (p=0.032), while smoker patients showed higher methylation rate at CpG6 (p=0.045).
Conclusion: These results manifested the contribution of DNA methylation of TGM-3 in OSCC and its potential association with clinico-pathologic parameters in OSCC.