bluuebunny/crossref_metadata_2025_split huggingface dataset:
How Did Educators of Students with Learning Differences Use Social–Emotional Learning to Support Their Students and Themselves Early in the COVID-19 Pandemic?
Authors: Eveleigh Abigail , Cook Amanda , Naples Lauren Hunter , Cipriano Christina 
Published: November 2021

Abstract
This study investigated the affective experiences of 30 educators of students with learning differences (sLD) and their use of social–emotional learning (SEL) early in the COVID-19 pandemic. Authors utilized a convergent parallel mixed-methods research design to collect and analyze data from educators through focus groups, interviews, and surveys. Through integrated analysis of qualitative and quantitative responses, authors found that educators of sLD experienced a range of emotions, both negative and positive, as they shifted to a virtual learning environment. Experiences of negative emotions were rooted in anxiety and stemmed from evolving demands and the increased challenges of adapting to distance learning, particularly for their sLD. Experiences of positive emotions stemmed from transformed relationships and new routes of communication with educators’ colleagues, students, and families. Importantly, SEL strategy use for themselves and with their students served as a useful tool in navigating the challenges that the educators were facing. Findings are discussed in the context of how best to support educators who work with sLD and utilize SEL to manage the challenges of distance learning.
Coil embolization to giant left anterior descending artery and left circumflex artery coronary artery aneurysm after failed coronary aneurysmal repair in IgG4-related disease: a case report
Authors: Pota Panupong , Suwannasom Pannipa , Woragidpoonpol Surin , Srisuwan Tanop 
Published: November 2021

Abstract

Background
IgG4-related disease (IgG4-RD) is a chronic fibroinflammatory condition with multiple-organ involvement. Rupture of coronary artery aneurysms (CAAs) in IgG4-RD is rare.

Case summary
A 65-year-old man with IgG4-RD has suffered from recurrent episodes of arterial aneurysms since 2003. He presented with chest pain and hypotension caused by localized cardiac tamponade at right ventricle free wall due to the rupture of coronary artery aneurysm (CAA) of left anterior descending artery (LAD). An urgent LAD aneurysm repaired with bovine pericardium and obliterated aneurysmal sac with cryo-acrylate glue was done together with coronary artery bypass grafting (CABG) using saphenous vein graft (SVG) to LAD and SVG to posterior descending artery. Three-month after surgery, the follow-up coronary computed tomography angiography (CCTA) revealed a growing in size of LAD and the second obtuse marginal (OM) branch aneurysm. Heart team discussion agreed to schedule the patient for double coil embolization to LAD and second OM aneurysm under intravascular ultrasound guidance. Both aneurysms were successfully obliterated with vascular coils. Two-week follow-up coronary angiogram showed complete occlusion of LAD aneurysm and near occlusion of the second OM branch aneurysm.

Discussion
Coronary artery aneurysm rupture is a life-threatening condition that required prompt detection and treatments. In IgG4-RD patients, acute cardiac tamponade suggesting the rupture of CAA. Coil embolization is an alternative treatment in patients who suffered from recurrent CAA after surgical repair. Serial CCTA is important for early detection of aneurysm in IgG4-RD patients who had vascular involvement.
Mitral regurgitation management: a systematic review of clinical practice guidelines and recommendations
Authors: Galusko Victor , Sekar Baskar , Ricci Fabrizio , Wong Kit , Bhattacharyya Sanjeev , Mullen Michael , Gallina Sabina , Ionescu Adrian , Khanji Mohammed Yunus 
Published: November 2021

Abstract
Multiple guidelines exist for the diagnosis and management of mitral regurgitation (MR), the second most common valvular heart disease in high-income countries, with recommendations that do not always match. We systematically reviewed guidelines on diagnosis and management of MR, highlighting similarities and differences to guide clinical decision-making. We searched national and international guidelines in MEDLINE and EMBASE (1 June 2010 to 1 September 2021), the Guidelines International Network, National Guideline Clearinghouse, National Library for Health Guidelines Finder, Canadian Medical Association Clinical Practice Guidelines Infobase, and websites of relevant organizations. Two reviewers independently screened the abstracts and identified articles of interest. Guidelines that were rigorously developed (as assessed with the Appraisal of Guidelines for Research and Evaluation II instrument) were retained for analysis.
Five guidelines were retained. There was consensus on a multidisciplinary approach from the heart team and for the definition and grading of severe primary MR. There was general agreement on the thresholds for intervention in symptomatic and asymptomatic primary MR; however, discrepancies were present. There was agreement on optimization of medical therapy in severe secondary MR and intervention in patients symptomatic despite optimal medical therapy, but no consensus on the choice of intervention (surgical repair/replacement vs. transcatheter approach). Cut-offs for high-risk intervention in MR, risk stratification of progressive MR, and guidance on mixed valvular disease were sparse.
Management of mitral stenosis: a systematic review of clinical practice guidelines and recommendations
Authors: Galusko Victor , Ionescu Adrian , Edwards Amy , Sekar Baskar , Wong Kit , Patel Ketna , Lloyd Guy , Ricci Fabrizio , Khanji Mohammed Y 
Published: November 2021

Abstract
A number of guidelines exist with recommendations for diagnosis and management of mitral stenosis (MS). We systematically reviewed existing guidelines for diagnosis and management of MS, highlighting their similarities and differences, in order to guide clinical decision-making. We searched national and international guidelines in MEDLINE and EMBASE (5/4/2011–5/9/2021), the Guidelines International Network, Guideline Library, National Guideline Clearinghouse, National Library for Health Guidelines Finder, Canadian Medical Association Clinical Practice Guidelines Infobase, and websites of relevant organizations. Two independent reviewers screened titles and abstracts, and the full text of potentially relevant articles where needed. Selected guidelines were assessed for rigor of development; only guidelines with Appraisal of Guidelines for Research and Evaluation II instrument score &gt;50% were included in the final analysis. Four guidelines were retained for analysis. There was consensus for percutaneous mitral balloon commissurotomy as first-line treatment of symptomatic severe rheumatic MS with suitable anatomy. In patients with unfavourable anatomy, surgical intervention should be considered. Exercise testing is indicated if discrepancy exists between symptoms and echocardiographic measurements. There was no clear divide between rheumatic MS and degenerative MS for their respective diagnoses and management. Pregnancy in severe MS is discouraged and the stenosis should be treated before conception. Long-term antibiotic prophylaxis is recommended for patients with rheumatic MS. Recommendations for the management of patients with mixed valvular diseases are lacking.
What Makes Heavy Metal ‘Heavy’?
Authors: Miller Jason 
Published: November 2021

AbstractIn this article, I raise a simple but surprisingly vexing question: What makes heavy metal heavy? We commonly describe music as “heavy,” whether as criticism or praise. But what does “heavy” mean? How is it applied as an aesthetic term? Drawing on sociological and musicological studies of heavy metal, as well as recent work on the aesthetics of rock music, I discuss the relevant musical properties of heaviness. The modest aim of this article, however, is to show the difficulty, if not impossibility, of this seemingly straightforward task. I first address the difficulties of identifying the defining features, or “Gestalt,” of heavy metal that would allow us to treat heaviness as a genre concept. Next, I discuss both the merits and the limits of analyzing heaviness in terms of an aesthetics of “noise” in rock music developed in recent philosophy of music. In the remaining sections, I consider other nonaesthetic features relevant to aesthetic judgments of heaviness and show that the term ‘heavy’ is conceptually inarticulable, if not irreducible. This, I conclude, has partly to do with the radically different, sometimes incompatible, musical properties present in the perception of musical heaviness.
The Use of Automated Traps to Assess the Efficacy of Insecticide Barrier Treatments Against Abundant Mosquitoes in Remote Environments
Authors: Johnson Brian J , Manby Russell , Devine Gregor J 
Published: November 2021

Abstract
Commercially available ‘smart’ trap technology has not yet been widely used to evaluate interventions against mosquitoes despite potential benefits. These benefits include the ability to capture data continuously at fine temporal scales without the human resources usually required for conventional trap deployment. Here, we used a commercially available smart trap (BG-Counter, Biogents) to assess the efficacy of an insecticide barrier treatment (BiFlex AquaMax) in reducing mosquito nuisance in a logistically challenging coastal environment in Queensland, Australia. Adoption of smart trap technology permitted us to conduct a uniquely detailed assessment of barrier treatments, ultimately allowing us to demonstrate significant reductions in mosquito collections from treated properties over all temporal scales. On average, daily mosquito collections from treated properties were reduced by 74.6% for the duration of the post-treatment period (56 d). This observation was supported by similar reductions (73.3%) in mosquito collections across all hours of the day. It was further found that underlying mosquito population dynamics were comparable across all study sites as evidenced by the high congruence in daily collection patterns among traps (Pearson r = 0.64). Despite limitations related to trap costs and replication, the results demonstrate that smart traps offer new precision tools for the assessment of barrier treatments and other mosquito control interventions.
Has breeding altered the light environment, photosynthetic apparatus, and photosynthetic capacity of wheat leaves?
Authors: Li Yu-Ting , Li Ying , Song Jian-Min , Guo Qian-Huan , Yang Cheng , Zhao Wen-Jing , Wang Jun-Yan , Luo Jiao , Xu Yan-Ni , Zhang Qiang , Ding Xin-Yu , Liang Ying , Li Yue-Nan , Feng Qiu-Ling , Liu Peng , Gao Hui-Yuan , Li Geng , Zhao Shi-Jie , Zhang Zi-Shan 
Published: November 2021

AbstractWhether photosynthesis has improved with increasing yield in major crops remains controversial. Research in this area has often neglected to account for differences in light intensity experienced by cultivars released in different years. Light intensity is expected to be positively associated with photosynthetic capacity and the resistance of the photosynthetic apparatus to high light but negatively associated with light-utilization efficiency under low light. Here, we analyzed the light environment, photosynthetic activity, and protein components of leaves of 26 winter wheat cultivars released during the past 60 years in China. Over time, light levels on flag leaves significantly decreased due to architectural changes, but photosynthetic rates under high or low light and the resistance of the photosynthetic apparatus to high light remained steady, contrary to expectations. We propose that the difference between the actual and expected trends is due to breeding. Specifically, breeding has optimized photosynthetic performance under high light rather than low light. Moreover, breeding selectivity altered the stoichiometry of several proteins related to dynamic photosynthesis, canopy light distribution, and photoprotection. These results indicate that breeding has significantly altered the photosynthetic mechanism in wheat and its response to the light environment. These changes likely have helped increase wheat yields.
The subthermal excitation of the C i lines in the molecular gas reservoirs of galaxies: its significance and potential utility
Authors: Papadopoulos P , Dunne L , Maddox S 
Published: November 2021

ABSTRACT
We examine a sample of 106 galaxies for which the total luminosities of the two fine structure lines 3P1 → 3P0, and 3P2 → 3P1 of neutral atomic carbon (C) are available, and find their average excitation conditions to be strongly subthermal. This is deduced from the CI(2-1)/(1-0) ratios ($\rm R^{(ci)}_{21/10}$) modeled by the exact solutions of the corresponding three-level system, without any special assumptions about the kinematic state of the concomitant $\rm H_2$ gas (and thus the corresponding line formation mechanism). This non-LTE excitation of the CI lines can induce the curious clustering of (CI,LTE)-derived gas temperatures near ∼25 K reported recently by Valentino et al. (2020), which is uncorrelated to the actual gas temperatures. The non-LTE CI line excitation in the interstellar medium of galaxies deprives us from a simple method for estimating molecular gas temperatures, and adds uncertainty in CI-based molecular gas mass estimates especially when the J = 2–1 line is used. However the $\rm R^{(ci)}_{21/10}$ = $\rm F(n, T_{k})$ ratio is now more valuable for joint CO/CI SLED and dust SED models of galaxies, and independent of the assumptions used in the CO radiative transfer models (e.g. the large velocity gradient approximation). Finally we speculate that the combination of low ratios $\rm R^{(ci)}_{21/10} \lesssim 1$ and high $\rm T_{dust}$ values found in some extreme starbursts indicates massive low-density molecular wind and/or circumgalactic gas reservoirs. If verified by imaging observations this can be a useful indicator of the presence of such reservoirs in galaxies.
Multiphase outflows in post-starburst E+A galaxies – I. General sample properties and the prevalence of obscured starbursts
Authors: Baron Dalya , Netzer Hagai , Lutz Dieter , Prochaska J Xavier , Davies Ric I 
Published: November 2021

ABSTRACT
E+A galaxies are believed to be a short phase connecting major merger ultraluminous infrared galaxies (ULIRGs) with red and dead elliptical galaxies. Their optical spectrum suggests a massive starburst that was quenched abruptly, and their bulge-dominated morphologies with tidal tails suggest that they are merger remnants. Active galactic nucleus (AGN)-driven winds are believed to be one of the processes responsible for the sudden quenching of star formation and for the expulsion and/or destruction of the remaining molecular gas. Little is known about AGN-driven winds in this short-lived phase. In this paper, we present the first and unique sample of post-starburst galaxy candidates with AGNs that show indications of ionized outflows in their optical emission lines. Using Infrared Astronomical Satellite–far infrared (IRAS–FIR) observations, we study the star formation in these systems and find that many systems selected to have post-starburst signatures in their optical spectrum are in fact obscured starbursts. Using SDSS spectroscopy, we study the stationary and outflowing ionized gas. We also detect neutral gas outflows in 40 per cent of the sources with mass outflow rates 10–100 times more massive than in the ionized phase. The mean mass outflow rate and kinetic power of the ionized outflows in our sample ($\dot{M}\sim 1\, \mathrm{M_{\odot }\, yr^{-1}}$, $\dot{E}\sim 10^{41}\, \mathrm{erg\, s}^{-1}$) are larger than those derived for active galaxies of similar AGN luminosity and stellar mass. For the neutral outflow ($\dot{M}\sim 10\, \mathrm{M_{\odot }\, yr^{-1}}$, $\dot{E}\sim 10^{42}\, \mathrm{erg\, s}^{-1}$), their mean is smaller than that observed in (U)LIRGs with and without AGN.
Searching for quasi-periodic oscillations in active galactic nuclei of the Chandra Deep Field South
Authors: Bao Tong , Li Zhiyuan 
Published: November 2021

ABSTRACT
Recent X-ray observations have revealed growing evidence of quasi-periodic oscillation (QPO) in the light curve of active galactic nuclei (AGNs), which may serve as a useful probe of black hole physics. In this work, we present a systematic search for X-ray QPOs among ∼1000 AGNs of the Chandra Deep Field South (CDF-S) in a homogeneous fashion. Dividing the 7-Ms Chandra observations into four epochs, we search for periodic signals that are persistent throughout any of these epochs, using two independent methods: Lomb–Scargle periodogram and Gregory–Loredo algorithm. No statistically significant periodic signal is found with either method on any of the four epochs. Our extensive simulations of source light curves suggest that this non-detection is primarily due to a moderate sensitivity of the CDF-S data in QPO detection. Using the simulation-predicted detection efficiency, we are able to provide a meaningful constraint on the intrinsic occurrence rate of persistent QPOs, $\lt (15\!-\!20)\,{{\mathrm{ per}\,\mathrm{ cent}}}$, provided that they share a similar power spectral density with a handful of currently known AGN QPOs. The true intrinsic occurrence rate might be significantly below this upper limit, however, given the non-detection among the CDF-S sources. Our additional search for short-lived QPOs that are only detected over a small subset of all observations results in two candidates, one in source XID 643 at a period of ∼13 273 s and the other in source XID 876 at a period of ∼7065 s.
InsectBase 2.0: a comprehensive gene resource for insects
Authors: Mei Yang , Jing Dong , Tang Shenyang , Chen Xi , Chen Hao , Duanmu Haonan , Cong Yuyang , Chen Mengyao , Ye Xinhai , Zhou Hang , He Kang , Li Fei 
Published: November 2021

Abstract
Insects are the largest group of animals on the planet and have a huge impact on human life by providing resources, transmitting diseases, and damaging agricultural crop production. Recently, a large amount of insect genome and gene data has been generated. A comprehensive database is highly desirable for managing, sharing, and mining these resources. Here, we present an updated database, InsectBase 2.0 (http://v2.insect-genome.com/), covering 815 insect genomes, 25 805 transcriptomes and &gt;16 million genes, including 15 045 111 coding sequences, 3 436 022 3′UTRs, 4 345 664 5′UTRs, 112 162 miRNAs and 1 293 430 lncRNAs. In addition, we used an in-house standard pipeline to annotate 1 434 653 genes belonging to 164 gene families; 215 986 potential horizontally transferred genes; and 419 KEGG pathways. Web services such as BLAST, JBrowse2 and Synteny Viewer are provided for searching and visualization. InsectBase 2.0 serves as a valuable platform for entomologists and researchers in the related communities of animal evolution and invertebrate comparative genomics.
Effectiveness and Safety of Tranexamic Acid Use in Acute Traumatic Injury in the Prehospital and In-hospital Settings: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Rowe Scott , Liu Amy , Zagales Israel , Awan Muhammad , Santos Radleigh , McKenney Mark , Elkbuli Adel 
Published: November 2021

Background and Objectives:
This systematic review and meta-analysis of randomized controlled trials (RCTs) aims to assess efficacy and safety of tranexamic acid (TXA) use in acute traumatic injuries.

Methods:
PubMed and Cochrane libraries were searched for relevant RCTs published between January 2011 and January 3, 2021. Cohen’s Q Test for heterogeneous effects was used to determine the appropriateness of fixed versus random effects models.

Results:
Twenty-two studies met inclusion criteria. Meta-analysis of relative risk of mortality between treatment and placebo groups in the in-hospital, and perioperative settings was not significant. However, the risk of mortality is significantly lower in the treatment versus placebo group when TXA was given as loading dose only. Ten of the 11 studies evaluating perioperative use of TXA included in systematic review found significantly lower blood loss in the treatment compared with placebo groups, but results of meta-analysis showed no significant difference. Results of meta-analysis indicate that the risk of venous thromboembolism (VTE) in the in-hospital treatment group is greater than that of the placebo. In subset analysis of studies using only a single loading dose, there were no significant differences in VTE.

Conclusions:
Systematic review supports TXA benefits are most evident when given shortly after injury and meta-analysis supports TXA reduces mortality as a single loading dose. Systematic review supports perioperative use of TXA when large volume blood loss is anticipated. Meta-results showed no significant difference in risk of thromboembolism in single-dose TXA treatment compared with placebo. These findings suggest that TXA is safe and effective for control of traumatic bleeding.
Considerations for Corneal Surgery With Patients in the 10th Decade of Life
Authors: Levine Harry , Naranjo Andrea , Martinez Jaime D. , Altamirano Diego S. , Gayer Steven , O'Brien Terrence P. , Karp Carol L. , Amescua Guillermo 
Published: November 2021

Purpose:
The purpose of this study was to report the indications, ocular and systemic comorbidities, and surgical outcomes of corneal transplantation in patients older than 90 years.

Methods:
A retrospective review was conducted to identify individuals 90 years and older who underwent corneal transplantation surgery at the Bascom Palmer Eye Institute between January 2013 and October 2020. Outcomes included best-corrected visual acuity and graft survival over time. Paired t tests were used to compare visual acuity preoperatively versus postoperatively. Graft survival was evaluated with Kaplan–Meier curves.

Results:
Fifty-eight eyes of 52 consecutive individuals were included. The mean age of individuals was 92 ± 2 years; 26.9% were male; and 48.1% self-identified as non-Hispanic White and 38.5% as Hispanic. Postoperative follow-up was 14.7 ± 12.1 months. Of the 58 eyes, 44.8% (26/58) underwent penetrating keratoplasty, 46.6% (27/58) Descemet stripping automated endothelial keratoplasty, and 6.9% (4/58) keratoprosthesis. All surgeries were performed under monitored local anesthesia, without major complications. Surgical indications included pseudophakic bullous keratopathy (36.2%), glaucoma-associated corneal decompensation (27.6%), Fuchs endothelial dystrophy (25.9%), and perforated corneal ulceration (19.0%). The best-corrected visual acuity improved by 0.32 (95% confidence interval 0.14–0.50; P < 0.01) as early as 1 month postoperatively, and vision gains were sustained for at least 12 months. Graft survival probability at 12 months was 88%.

Conclusions:
Corneal transplantation is a safe and successful procedure in restoring the visual acuity for patients older than 90 years after careful preoperative evaluation. Further research is needed to evaluate the impact of corneal transplantation on quality of life in patients in the 10th decade of life.