bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical features and outcome of patients with autoimmune cerebellar ataxia evaluated with the Scale for the Assessment and Rating of Ataxia
Authors: Damato Valentina , Papi Claudia , Spagni Gregorio , Evoli Amelia , Silvestri Gabriella , Masi Gianvito , Sabatelli Eleonora , Campetella Lucia , McKeon Andrew , Andreetta Francesca , Riso Vittorio , Monte Gabriele , Luigetti Marco , Primiano Guido , Calabresi Paolo , Iorio Raffaele 
Published: October 2021

AbstractBackground and purposeThis study was undertaken to assess the long‐term outcome of patients with paraneoplastic and non paraneoplastic autoimmune cerebellar ataxia (ACA) using the Scale for the Assessment and Rating of Ataxia (SARA).MethodsPatients with subacute cerebellar ataxia admitted to our institution between September 2012 and April 2020 were prospectively recruited. Serum and/or cerebrospinal fluid was tested for neural autoantibodies by indirect immunofluorescence on mouse brain, cell‐based assays, and radioimmunoassay. SARA and modified Rankin Scale (mRS) score were employed to assess patients’ outcome.ResultsFifty‐five patients were recruited, of whom 23 (42%) met the criteria for cerebellar ataxia of autoimmune etiology. Neural autoantibodies were detected in 22 of 23 patients (Yo–immunoglobulin G [IgG], n = 6; glutamic acid decarboxylase 65–IgG, n = 3; metabotropic glutamate receptor 1–IgG, n = 2; voltage‐gated calcium channel P/Q type–IgG, n = 2; Hu‐IgG, n = 1; glial fibrillary acidic protein–IgG, n = 1; IgG‐binding unclassified antigens, n = 7). Thirteen patients were diagnosed with paraneoplastic cerebellar syndrome (PCS) and 10 with idiopathic ACA. All patients received immunotherapy. Median SARA score was higher in the PCS group at all time points (p = 0.0002), while it decreased significantly within the ACA group (p = 0.049) after immunotherapy. Patients with good outcome (mRS ≤ 2) had less neurological disability (SARA < 15) at disease nadir (p = 0.039) and presented less frequently with paraneoplastic neurological syndrome (p = 0.0028). The univariate linear regression model revealed a good correlation between mRS and SARA score both at disease onset (p < 0.0001) and at last follow‐up (p < 0.0001). SARA score < 11 identified patients with good outcome.ConclusionsPatients with idiopathic ACA significantly improved after immunotherapy. SARA score accurately reflects patients’ clinical status and may be a suitable outcome measure for patients with ACA.
Global distribution of the South American peacock bassesCichlaspp. follows human interference
Authors: Franco Ana Clara Sampaio , Petry Ana Cristina , Tavares Marcela Rosa , de Fátima Ramos Guimarães Taís , dos Santos Luciano Neves 
Published: October 2021

AbstractSouth American peacock basses (genusCichla) have been widely introduced within and outside the Neotropical region due to their importance to fisheries, despite threats to the native fish fauna. We performed a literature review on the worldwide distribution of validCichlaspecies by focusing on records of species richness and populations in their native and non‐native ranges. We tested for an effect of area, the number of large dams, human population density and gross domestic product as drivers of the distribution of peacock basses across the Freshwater Ecoregions of the World (FEOWs). A total of 544 studies led to 1,289 records of nine species. Their distributions within their native range (19 native FEOWs) were narrower than their distributions in their non‐native range (23 non‐native FEOWs), which encompass tropical and subtropical ecoregions of the Americas, Africa, Southeast Asia and the Pacific islands. Several of these FEOWs harboured more than one species, usuallyC. ocellarisandC. piquiti. Ecoregion areas were positively associated with species richness and population records in native FEOWs, whereas the number of reservoirs was positively related to the records of non‐native populations. These patterns provide further evidence of the role played by reservoirs as the main pathway for the introduction of peacock basses; thus, special attention should be given to the continuous monitoring of the spread of these invaders across watersheds in invaded ecoregions. Considering their broad distribution and the potential for peacock basses to thrive in human‐modified systems, severe damage to the native fish fauna is predicted.
The efficacy of Lactobacillus acidophilus and rhamnosus in the reduction of bacterial load of Helicobacter pylori and modification of gut microbiota—a double‐blind, placebo‐controlled, randomized trial
Authors: Chen Mei‐Jyh , Chen Chieh‐Chang , Huang Yu‐Chun , Tseng Chieh‐Chih , Hsu Jing‐Ting , Lin Yi‐Fen , Fang Yu‐Jen , Wu Ming‐Shiang , Liou Jyh‐Ming ,   for the Taiwan Gastrointestinal Disease, Helicobacter Consortium
Published: October 2021

AbstractBackgroundProbiotics may alter the gut microbiota and may reduce antibiotic‐related dysbiosis after H. pylori eradication. However, whether probiotics are effective in reducing the bacterial load of H. pylori and modifying the gut microbiota remains unknown. We aimed to assess the efficacy of Lactobacillus acidophilus and Lactobacillus rhamnosus in reducing the bacterial load of H. pylori and modifying the gut microbiota.Materials and methodsIn this double‐blind, randomized, placebo‐controlled trial, we recruited 40 adult subjects with moderate to high bacterial loads of H. pylori, defined as a mean delta over baseline (DOB) value of the 13C‐urea breath test (13C‐UBT) of 10 or greater every 4 days 6 times. Eligible subjects were randomized in a 1:1 ratio to receive either probiotics containing Lactobacillus acidophilus and Lactobacillus rhamnosus or placebo twice daily for 4 weeks. 13C‐UBT was measured weekly from the beginning of treatment to 2 weeks after treatment. Amplification of the V3 and V4 hypervariable regions of the 16S rRNA was performed for fecal microbiota.ResultsA total of 40 subjects were randomized to receive probiotics or placebo. The DOB value was significantly lower in the probiotic group than in the placebo group after 4 weeks of treatment (26.0 vs. 18.5, p = .045). The DOB value was significantly reduced compared to that at baseline in the probiotic group (18.5 vs. 26.7, p = .001) but not in the placebo group (26.0 vs. 25.0, p = .648). However, the eradication rate for H. pylori was 0% in both groups. There was no significant difference in the DOB values between the two groups 1 and 2 weeks after discontinuation of the probiotics. There were also no significant changes observed in the α‐diversity and β‐diversity at week 4 compared to baseline in the probiotic group (p = .77 and 0.91) and the placebo group (p = .26 and 0.67).ConclusionsAlthough the use of Lactobacillus acidophilus and Lactobacillus rhamnosus may reduce the bacterial load of H. pylori, there were no significant changes in the composition of gut microbiota. This trial is registered with ClinicalTrials.gov, NCT02725138.
Proveedores surcoreanos de primer nivel en las cadenas mundiales de valor de la confección. Upgrading e implicaciones laborales en el contexto asiático
Authors: KWON Hyunji , CHUNG Sun Wook , LEE Joonkoo 
Published: October 2021

ResumenSe analiza la evolución histórica de los proveedores de prendas de vestir en la República de Corea, en particular el auge de proveedores de primer nivel (PPN), a partir de los casos de los dos principales: cómo ampliaron su presencia internacional, especialmente en Asia, hasta convertirse en grandes multinacionales, cómo evolucionaron tras la crisis financiera internacional de 2008, y cómo, tras su rápido crecimiento hasta crear un entorno empresarial complejo, han ocupado una posición estratégica en las reconfiguradas cadenas mundiales de valor de la confección. También se examinan sus respuestas a los problemas laborales, considerando lo que su upgrading implica para los trabajadores.
Producing industrial pigs in southwestern China: The rise of contract farming as a coevolutionary process
Authors: Zhang Qian Forrest , Zeng Hongping 
Published: October 2021

AbstractThe literature on contract farming (CF) has to date focused on how outside capital uses CF to vertically integrate non‐capitalist producers into agro‐industrial value chains. We argue that in places where multiple dynamics of capitalist growth co‐exist, CF relationships can also emerge between different types of capitalist producers that are already in capitalist production using other organizational forms. In this situation, the well‐studied drivers that fuel the spread of CF become less consequential; the emergence of CF is instead more contingent on the complex interactions between producers and the specific conditions and events in the local environment. We conceptualize the emergence of this type of CF as a coevolutionary process and develop an analytical toolkit from this perspective to study the rise of CF in industrial pig farming in a Chinese county. Our analysis traces the evolution of agro‐industrialization over a decade (2006–2016) and shows the emergence of CF as a coevolutionary outcome shaped by the unique biography of the contract producers, the “historical accident” of a market downturn, and the reciprocal responses between contract producers and agribusinesses.
The anti‐wrinkles properties of sodium acetylated hyaluronate
Authors: Meunier Marie , Scandolera Amandine , Chapuis Emilie , Lapierre Laura , Sandré Jérôme , Brunner Gerhard , Lovchik Martin , Reynaud Romain 
Published: October 2021

AbstractBackgroundIntrinsic aging promotes wrinkles formation by an imbalance between matrix synthesis/degradation in favor of degradation. This is accelerated by the exposome leading to overproduction of protease and fewer remodeling.ObjectiveProtecting the integrity of extracellular matrix appears as the most efficient anti‐aging solution. We developed a grafted HA specifically designed to get anti‐aging property due to a specific molecular weight and acetylation degree.MethodsA transcriptomic analysis was performed on fibroblasts, followed by a measurement of MMP secretion and subsequent effect on collagen degradation. MMP expression in skin explants concerned by chronobiological and extrinsic aging was analyzed by immunostaining. A clinical study was conducted on volunteers presenting wrinkles on face to evaluate flash reduction of wrinkles after 6 h of application by profilometry and anti‐aging efficacy after 2 months by VISIA® CR2.3.ResultsTranscriptomic analysis evidenced an inhibition of MMP gene expression with acetylated HA, confirmed by an inhibition of MMPs release by fibroblasts, and a protection of type I collagen against degradation. We confirmed the reduction of MMPs in mature skin and in skin explants exposed to UV and urban dust. We demonstrated during clinical studies the flash reduction effect of acetylated HA on crow's feet wrinkles and a filling of nasogenian areas 6 h after application, and a wrinkles number reduction on nasogenian area up to 2 months of application.ConclusionWe developed a new grafted HA owing protective properties against ECM degradation induced by chronobiological and extrinsic aging, leading to a significant and efficient anti‐wrinkles effect.
Predıctıve value of pregnancy of follıcular fluıd fetuın‐A and ‐B levels ın infertıle women after intra‐cytoplasmic sperm injection
Authors: Yurtcu Nazan , Oral Serkan , Celik Sebahattin , Calıskan Suleyman Tumer , Alagoz Murat , Dahan Michael H. 
Published: October 2021

AbstractAimWe aimed to investigate the value of follicular fluid fetuins‐A and ‐B to predict successful IVF and pregnancy outcomes in infertile women with poor, normal, and high ovarian reserve.MethodsThe follicular fluid of 96 infertile women who underwent intra‐cytoplasmic sperm injection (ICSI) procedure was analyzed. Fetuins‐A and ‐B levels were examined and compared in those who could achieve pregnancy and those who could not. Receiver operating characteristic curve analyzes were used to determine cut‐off and statistically significant associations for fetuins‐A and ‐B.ResultsFollicular fluid fetuin‐A levels were higher in cases with weak ovarian reserve (OR) (p < 0.05) and higher in patients who did not achieve clinical pregnancy (p < 0.05). Conversely, the follicular fluid fetuin‐B levels were lower in cases with poor OR (p < 0.05) and were lower in patients who did not achieve a clinical pregnancy (p < 0.05). A follicular fluid fetuin‐A concentration ≤ 19.12 ng/mL had a sensitivity and specificity of 94.74% and 93.1%, respectively, at predicting clinical pregnancy. While the follicular fluid fetuin‐B concentration >24.7 ng/mL had sensitivity and specificity of 71.1% and 51.7%, respectively, for clinical pregnancy prediction.ConclusionOverall, high levels of follicular fluid fetuin‐A may be independently associated with unsuccessful IVF irrespective of OR grouping. A low level of follicular fetuin‐B was also associated with failed IVF. The sensitivity and specificity were found to be higher for fetuin‐A in predicting clinical pregnancy. Therefore, the follicular fluid fetuin‐A may be more predictive for successful IVF and clinical pregnancy outcomes than follicular fluid fetuin‐B.
The taboo against contact with minorities: A folk‐anthropology approach to prejudices
Authors: Pérez Juan A. 
Published: October 2021

AbstractIn contrast to the classic theory of contact among groups to combat prejudice against the outgroup (Allport, 1954), we propose the theory of the taboo of contact according to which prejudice against minorities does not arise due to lack of contact, but precisely in order to avoid contact. We summarise a series of themata whereby in the West the majority's fears of losing the purity of their religious, ethnic, or racial identity have been ontologised in four minorities (Jews, gypsies, natives, and black people). The hypothesis is that the greater the proximity to – or danger of mixing with – those vilified minorities, the greater the taboo of contact will be. We conclude that the prejudice against minorities who are victims of current ethnic and racial discrimination is an hysteresis effect of folk‐anthropology themata.
The influence of environmental parameters on the phytoplankton community of two tropical reservoirs
Authors: Chappell Jessica , Whitmire Stefanie , Sotomayor‐Ramírez David , Martínez Gustavo 
Published: October 2021

AbstractPrevious studies have indicated certain environmental variables such as rainfall, nutrient concentrations and mixing events can be strong drivers of the phytoplankton community structure in reservoirs. Shifts in the phytoplankton community composition of Puerto Rican reservoirs, however, are not well understood. The present study identified the spatial and temporal changes in the phytoplankton community structure of two reservoirs in Puerto Rica, and which environmental parameters determined the structure. Whether or not the main environmental variables varied on the basis of the initial trophic status of the reservoirs was also explored. Two Puerto Rican reservoirs, one classified as mesotrophic and the other as eutrophic, were sampled on three sampling dates, with the reservoirs into three zones (dam; transition; riverine). Physical parameters were recorded at each sampling site, nutrient concentrations were measured, and the phytoplankton community biomass and diversity were determined. A canonical correspondence analysis (CCA) was run for each reservoir to explore which variables determined the phytoplankton community composition. Temperature, pH and total phosphorus concentration were the main drivers of the phytoplankton community composition for the mesotrophic reservoir, while specific conductance, pH, total phosphorus and nitrate were the main explanatory variables. Although the driving variables changed between the reservoirs, the temporal shifts observed in the phytoplankton community structure were consistent for both reservoirs regardless of their trophic status. The findings of the present study suggest that, although shifts in the phytoplankton community structure are similar in reservoirs with differing initial trophic status, the environmental variables driving community composition may nevertheless vary. Accordingly, tropical reservoirs managers should consider a reservoir's initial trophic status when evaluating what environmental parameters may lead to changes in its phytoplankton community structure. The present study represents a first step at examining the variables driving phytoplankton community structure in Puerto Rican reservoirs.
Capacidad de investigación en obesidad infantil en Latinoamérica y en las poblaciones latinas de Estados Unidos: estado de la investigación, problemas, oportunidades y líneas de trabajo para el futuro
Authors: Salvo Deborah , Parra Diana C. , Jáuregui Alejandra , Resendiz Eugen , Garcia‐Olvera Armando , Velazquez Daniel , Aguilar‐Farias Nicolas , Colón‐Ramos Uriyoán , Hino Adriano A. , (Bill) Kohl Harold W. , Pratt Michael , Varela Andrea Ramirez , Ramirez‐Zea Manuel , Rivera Juan A. 
Published: October 2021

ResumenLa obesidad infantil es un problema grave en Latinoamérica y entre la población latina de EE. UU. Para ser eficaces, las políticas de salud pública tienen que estar guiadas por evidencias contextuales pertinentes, lo cual exige una capacidad de investigación sostenida a través del tiempo. Los objetivos de este estudio son determinar la productividad de la investigación enfocada en las poblaciones latinas en Latinoamérica y Estados Unidos, y examinar los dominios de la capacidad de investigación (infraestructuras, programas de formación, mentoría, financiamiento y redes de contactos). Realizamos una revisión exploratoria de artículos indexados relacionados con la obesidad infantil publicados entre junio de 2015 y diciembre de 2019. Recabamos información sobre las percepciones de los investigadores latinoamericanos respecto a la capacidad de investigación en obesidad infantil a través de una encuesta en línea. Identificamos 612 artículos relacionados con la obesidad infantil (505 de Latinoamérica, 124 de EE. UU. y 17 de colaboraciones entre EE. UU. y Latinoamérica). Brasil, México, Chile, Colombia y Estados Unidos son los países con más publicaciones. Encontramos aproximadamente el mismo número de artículos sobre obesidad, nutrición y actividad física; sin embargo, observamos que la capacidad de investigación sobre actividad física está rezagada en otros dominios (formación en investigación, financiamiento y oportunidades para establecer contactos). Otras áreas de investigación complementarias, como el comportamiento sedentario, la ciencia de sistemas y los estudios de políticas, son poco frecuentes en Latinoamérica, pero más habituales en Estados Unidos, mientras que la investigación sobre el sueño es incipiente en ambas regiones. Para cumplir la promesa de crear un programa eficaz de colaboración transfronteriza para la prevención de la obesidad infantil será necesario invertir en todos los dominios de la capacidad de investigación y en todos los temas pertinentes.
La migración como determinante de la obesidad infantil en Estados Unidos y Latinoamérica
Authors: Vilar‐Compte Mireya , Bustamante Arturo V. , López‐Olmedo Nancy , Gaitán‐Rossi Pablo , Torres Jaqueline , Peterson Karen E. , Teruel Graciela , Pérez‐Escamilla Rafael 
Published: October 2021

ResumenLa migración internacional tiene consecuencias económicas y en la salud. El proceso de aculturación en el país de acogida puede estar relacionado con la obesidad infantil. Utilizamos el marco conceptual del balance energético comunitario (CEB, por sus siglas en inglés) para analizar la relación entre migración y obesidad infantil en los hogares mexicanos con migrantes internacionales. Utilizando datos longitudinales de la Encuesta Nacional de Niveles de Vida de los Hogares de México (ENNViH), examinamos cómo influyen las redes de migrantes sobre la obesidad infantil en las comunidades de origen. También revisamos programas de salud binacionales que podrían ser eficaces para abordar la obesidad infantil en los hogares de migrantes procedentes de México. Los niños que forman parte de las redes de migrantes presentan un mayor riesgo de ‐desarrollar sobrepeso y obesidad, lo cual sugiere una relación significativa entre la obesidad infantil y la migración internacional en los hogares mexicanos. Basándonos en los criterios de búsqueda que habíamos definido, realizamos un análisis de programas de extensión comunitaria en salud cuyos resultados indican que las Ventanillas de Salud (VDS) son una opción prometedora para prevenir la obesidad infantil en un entorno de confianza y culturalmente sensible. El marco conceptual CEB es útil para comprender cómo contribuye la migración al riesgo de sobrepeso y obesidad infantil en los hogares de los migrantes. Las VDS son una estrategia viable y replicable con un gran potencial para abordar la obesidad infantil entre las familias migrantes y que toma en cuenta los determinantes dinámicos y binacionales de la obesidad infantil.
Exposición a químicos disruptores endócrinos obesogénicos y obesidad en niños y jóvenes de origen latino o hispano en Estados Unidos y Latinoamérica: una perspectiva del curso de la vida
Authors: Perng Wei , Cantoral Alejandra , Soria‐Contreras Diana C. , Betanzos‐Robledo Larissa , Kordas Katarzyna , Liu Yun , Mora Ana M. , Corvalan Camila , Pereira Anita , Cardoso Marly Augusto , Chavarro Jorge E. , Breton Carrie V. , Meeker John D. , Harley Kim G. , Eskenazi Brenda , Peterson Karen E. , Tellez‐Rojo Martha Maria 
Published: October 2021

ResumenEn el 2019, en seguimiento a un taller dirigido por el Global Health Studies del Fogarty International Center sobre el tema de la prevención de la obesidad infantil y las sinergias de investigación que surgen a través de las colaboraciones transfronterizas, convocamos a un grupo de expertos de Estados Unidos y Latinoamérica para que realizaran una revisión narrativa de la literatura epidemiológica sobre el papel obesogénico de los químicos disruptores endócrinos (EDC, por sus siglas en inglés) en la etiología de la obesidad infantil entre la juventud latina de Estados Unidos y Latinoamérica. Además de resumir y sintetizar los resultados de las investigaciones sobre este tema publicados en la última década, contextualizamos los hallazgos dentro de un marco bioconductual de curso de vida para identificar relaciones exposición‐desenlace impulsadas por resultados de investigación, identificar inconsistencias y deficiencias de la literatura actual, y discutir el papel de las regulaciones políticas, todo con el objetivo de identificar posibles vías para la prevención temprana de la obesidad en las poblaciones hispanas/latinas.
“That's Why I Do What I Do”: Southern Black feminism in philosophy
Authors: Stewart Lindsey 
Published: October 2021

AbstractAlice Walker claims that the “advantageous heritage” of Black southern life is replete with intellectual meat for thinking and writing. How might the insights found in this “advantageous heritage” enrich our discussions of Black feminism in philosophy? Taking stock of this “advantageous heritage” is no mean feat in the discipline of philosophy as it sits at the intersection of two subfields that are already marginalized: Black feminist philosophy and southern philosophy. To help situate southern Black feminist philosophy, I draw upon Kristie Dotson's model of “inheritance maps,” or an “attempt to take stock of what one has been given in a particular project and what one inherits as work yet to do.” Focusing primarily on the theme of refusal, I develop an “inheritance map” that lays out aspects of southern Black feminism that I have inherited from Angela Davis'sBlues Legacies and Black Feminism.