bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Matemática do Ensino e os Documentos Curriculares: Bases Teórico-Metodológicas Para Análise da Produção de Novos Saberes
Authors: Valente Wagner Rodrigues 
Published: April 2021

ResumoComo historicamente é possível realizar a análise dos processos e dinâmicas de elaboração de novos saberes para o ensino de matemática e para a formação do professor que ensina matemática fixados em documentos curriculares? Buscando responder a esta questão o objetivo deste texto é analisar que bases teórico-metodológicas podem ser mobilizadas de modo a ser possível caracterizar a matemática do ensino, constructo teórico que articula a matemática do ensino e a matemática da formação de professores. A análise envolve metodologia vinda do campo histórico. Dentre os autores mobilizados para desenvolvimento do estudo estão Chervel (1990) e os seus trabalhos sobre história das disciplinas escolares; também Julia (2000) e a introdução do conceito de cultura escolar; Hofstetter & Schneuwly (2020) e os saberes para a formação de professores, dentre outros. Como resultados apontam-se três referências fundamentais: a sócio-história, a mobilização do conceito de experts e o uso das variações de escala.
Palavras-chave: Sócio-História. Experts. Currículo. Formação de Professores. Matemática
AbstractHow historically is it possible to analyze processes and dynamics for the development of new knowledge for the teaching of mathematics and for the training of teachers who teach mathematics fixed in curricular documents? Seeking to answer this question, the objective of this text is to analyze which theoretical and methodological bases can be mobilized in order to be able to characterize mathematics from teaching, a theoretical construct that articulates mathematics to teach and the mathematics for teaching. The analysis involves methodology from the historical field. Among the authors mobilized for the development of the study are Chervel (1990) and his works on the history of school subjects; also Julia (2000) and the introduction of the concept of school culture; Hofstetter & Schneuwly (2020) and the knowledge for teacher training, among others. As results, three fundamental references are pointed out: socio-history, the mobilization of the concept of experts and the use of variations in scales.
Keywords: Socio-History. Experts. Curriculum. Teacher Training. Mathematics.
Disección anatómica del oído medio y el oído interno
Authors: Osorio-Toro Sonia , Moreno-Restrepo Wilmer Andrés , Torres-Gaviria Nathalie , Zúñiga-Prado Janneth Rocio 
Published: May 2021

Introducción: El oído medio y el oído interno presentan una compleja constitución anatómica; La disección como método de enseñanza proporciona una comprensión óptima de la configuración tridimensional de sus estructuras debido a su carácter práctico y realista. Se propone un protocolo de disección aislada del oído medio e interno que ofrece una visión amplia de sus estructuras e incorpora esquemas didácticos. Material y Método: En tres cadáveres humanos en estado de conservación se delimitaron dos cuadrángulos en la cara superior del hueso temporal mediante referentes anatómicos para extraer una estructura paralelepípeda correspondiente a la porción petrosa del hueso temporal, sobre la cual se realizó disección. Resultados: Se creó un protocolo de disección siguiendo esta secuencia: Extracción parcial de la porción petrosa del hueso temporal, visualización del oído medio, exposición de la membrana timpánica y visualización del oído interno. Conclusión: Esta herramienta pedagógica es aplicable al proceso de enseñanza y constituye un recurso cuyo carácter didáctico resulta potencialmente útil para los estudiantes facilitando el aprendizaje activo de los aspectos teóricos y prácticos del oído.
Rupturing the Silences: Intergenerational Construction of Salvadoran Immigrant War Necronarratives
Authors: Trujillo Ester N. 
Published: May 2021

Abstract
As the children of wartime immigrants from El Salvador become adults, they must grapple with the role violence played—and continues to play—in Salvadoran society. Second-generation Salvadorans interpret their relatives’ stories of war, death, and violence through a lens that prioritizes lessons gained over traumatization. Thus, immigrant parents’ casual discussions about their experiences during the Salvadoran Civil War (1979–1992) become what this article calls necronarratives: stories pieced together from memories based on foiling death and violence generated through state necropolitics. Youth interpret inherited memories through a lens of survival, resilience, and healing. Necropolitics refers to the ability of the state to legislate and draw policies that determine who lives and who dies. Although scholars have noted that high levels of war-related trauma among Salvadoran immigrants cause them to remain silent about those experiences, my research reveals that children of these immigrants collect and construct narratives using the memory fragments shared during casual conversations with their relatives. Drawing from 20 semi-structured interviews with U.S. Salvadorans, this paper shows that U.S. Salvadorans construct narratives out of their family’s war memories in order to locate affirming qualities of the Salvadoran experience such as surviving a war, achieving migration, and building a life in a new country. Contrary to past indications that Central American migrants live in silence about their national origins in order to avoid discrimination in the U.S. and to avoid traumatizing their children, this study on second-generation Salvadoran adults describes the ethnic roots information families do share through war stories. The Salvadoran case shows youth actively engage with necronarratives as they come of age to adulthood to yield lessons about how their national origins and ethnic heritages shape their senses of belonging and exclusion within U.S. society.
Studi Perilaku Investor dan Myopic Loss Aversian
Authors: Septiani Rizki , Maharani Satia Nur , Ermayda Ria Zulkha 
Published: May 2021

An experienced investor's mindset tends to be different from that of a novice investor who has certain considerations heavily influenced by feelings and emotions. This mindset has unwittingly led to behavioral bias. One behavioral bias that often arises without being realized by investors, especially novice investors, is Myopic Loss Aversion (MLA). This study aimed to confirm the existence of Myopic Loss Aversion (MLA) behavioral bias and to analyze Myopic Loss Aversion (MLA) behavior bias inactive investors in Malang as well as the factors causing the emergence of Myopic Loss Aversion (MLA) behavior bias. This research was qualitative case study research. Primary data was obtained through in-depth interviews with selected informants. The results found that Myopic Loss Aversion arises in investors who conduct portfolio evaluations more frequently by monitoring fluctuating stock chart movements that seem to fear that their portfolio would suffer losses. Furthermore, another discovery was about how investors who had experienced Myopic Loss Aversion bias could overcome past mistakes in the investment decision-making process.Keywords: Financial Behavior, Investors, Investment Decision Making AbstrakPola pikir investor yang sudah berpengalaman bisa berbeda dengan investor pemula yang cenderung masih memiliki pertimbangan tertentu yang banyak dipengaruhi oleh perasaan dan emosi. Pola pikir ini tanpa disadari telah memunculkan bias keperilakuan. Salah satu bias keperilakuan yang sering muncul tanpa disadari oleh investor terutama investor pemula yaitu Myopic Loss Aversian (MLA). Penelitian ini bertujuan untuk mengkonfirmasi eksistensi dari bias keperilakuan Myopic Loss Aversian (MLA) dan menganalisis bias perilaku Myopic Loss Aversian (MLA) pada investor aktif di Malang serta faktor penyebab munculnya bias perilaku Myopic Loss Aversian (MLA). Penelitian ini merupakan penelitian kualitatif studi kasus. Data primer dilakukan melalui wawancara mendalam terhadap informan terpilih. Hasil penelitian ini ditemukan bahwa Myopic Loss Aversian muncul pada investor yang melakukan evaluasi portofolio secara lebih frekuen melaui pemantauan pergerakan grafik harga saham fluktuatif yang seakan-akan takut portofolionya mengalami kerugian. Lebih lanjut, juga ditemukan tentang bagaimana para investor yang pernah mengalami bias Myopic Loss Aversian mengatasi kesalahan-kesalahan dimasa lalu dalam proses pengambilan keputusan investasi.Kata Kunci: Perilaku Keuangan, Investor, Pengambilan Keputusan Investasi
Preparing future teachers to use digital educational resources in primary school
Authors: Aidarbekova Kulzhan A. , Abildina Saltanat K. , Odintsova Svetlana A. , Mukhametzhanova Aigul O. , Toibazarova Nagimash A. 
Published: May 2021

The use of digital educational resources is based on ensuring that control measures are fixed and that the educational process as a whole is more transparent. The purpose of this article is to research the use of digital educational resources in primary school. The methodological basis of the study is determined by the possibility of using the design method. The novelty of the study is determined by the fact that the digital educational environment is understood primarily as the function of knowledge transfer and the desire to combine conventional teaching methods with innovative principles. It was concluded that the digital environment should be designed and taught to future teachers not only as an applied subject but also as an infrastructural component. By comparing the experimental and control groups, the authors empirically confirmed that pedagogical influence using web-based technologies is more effective than previously used ones.

Keywords: blended learning; education; conventional teaching; technologies; web resources.
Specific features of value orientations among the student youth in the context of digital transformation of the education system
Authors: Khammatova Rina S. , Gribkova Olga V. , Tkhugo Muliat M. , Ushakova Olga B. , Shchetinina Nina N. , Krasheninnikova Ekaterina I. , Erofeeva Maria A. 
Published: May 2021

The importance of the paper is determined by the fact that the development of digital technologies is currently one of the main priorities of any country, both at the highest political level and at the federal and regional ones. The introduction of digital initiatives into the education system leads to their reforming, which has a direct influence on all subjects of the educational process. The goal of the study was to investigate the characteristics of the value orientations of student youth in the context of the digital transformation of the higher education institution. The research methods comprised theoretical and methodological analyses of the problem, empirical research methods (testing, interviewing and a survey), an educational experiment and methods of mathematical statistics. The results of the study include a description of the value framework structure of the personality of student youth (values and meanings) in the era of digital transformation. In addition, as a result of the study, the authors of the paper designed and tested a programme of additional education for students, aimed at developing the value orientations of the ‘digital personality’. The materials of the paper can be useful for the introduction into the educational process in the system of higher and secondary vocational education.

Keywords: Value orientations, student youth, global risks and challenges, information and educational environment of a higher education institution, digital transformation of society.
International Consensus on Antinuclear Antibody em Portugal
Authors: Sousa Maria José , Neves Esmeralda , Figueiras Otília , Cruz Ana Paula , Fernandes Isabel , Mendes Alexandra , Santos Maria do Céu , Cunha Rosário , Magueijo Lídia , Pratas Cláudia , Miranda Ana , Ribeiro Rita 
Published: May 2021

Introdução: A pesquisa de autoanticorpos em células HEp-2 através de imunofluorescência indireta é o teste padrão atualmente aceite como a ferramenta central para o diagnóstico das doenças autoimunes sistémicas. O International Consensus on Antinuclear Antibody (ANA) Patterns tem como objetivo principal alcançar um consenso na nomenclatura e na descrição dos diferentes padrões morfológicos de anticorpos antinucleares. Este trabalho tem como objetivo ampliar o projeto do International Consensus on ANA Patterns de forma a estabelecer um consenso em Portugal para a sua nomenclatura, procurando contribuir para a harmonização no diagnóstico autoimune e promover a qualidade diagnóstica nas doenças reumáticas sistémicas autoimunes.Material e Métodos: Os laboratórios participantes identificaram cada designação de padrão citoplasmático e nuclear do International Consensus on ANA Patterns (incluindo o código padrão anti-célula), e fizeram corresponder a cada uma a respetiva nomenclatura portuguesa em uso. Os resultados foram agregados e serviram de base ao trabalho de harmonização da nomenclatura. Seguiram-se reuniões de consenso, num processo iterativo até à redação de uma proposta final consensualizada.Resultados: A concordância prévia entre laboratórios era superior a 75% para 23 do total de 29 padrões anti-célula. O grau em que cada laboratório está alinhado com a referência internacional do International Consensus on ANA Patterns varia entre 22,1% e 100%. Foi possível elaborar uma versão consensualizada da nomenclatura do International Consensus on ANA Patterns para Portugal.Discussão: Existia uma boa base de consenso para a nomenclatura do International Consensus on ANA Patterns, mas com diferenças importantes em algumas das traduções da terminologia. O estudo realça a necessidade de colaboração entre laboratórios para uma descrição inequívoca dos resultados laboratoriais.Conclusão: Este trabalho mostra o potencial positivo da colaboração entre laboratórios para gerar consensos que contribuam para a melhoria do diagnóstico e acompanhamento dos doentes.
REVIEW ASSESSMENT OF BIODIVERSITY LOSS OF SUNDARBAN FOREST: HIGHLIGHTS ON CAUSES AND IMPACTS
Authors: Khan Md. Shohel , Abdullah Shahriar , Salam Mohammed Abdus , Mandal Tanwee Rani , Hossain Md. Rajib 
Published: May 2021

Sundarban, the world biggest mangrove forest, was announced as a World Heritage in 1997 and Ramsar Site in 2007. It's 62% lies in Bangladesh (Khulna, Bagerhat, Satkhira, Pirojpur, and Barguna Regions) and 38% in India, which become a vanguard for coastal communities. This ecosystem's floral and faunal structure incorporates 334 floral, 300 birds, 120 fish, 35 reptiles, and 32 mammals species. It contributes 41% of the total forest income of Bangladesh. This paper is intended to recognize the significant reasons for biodiversity calamity and its related effects on lives and degradation of the environment. A total of 105 published articles and reports were identified by searching four keywords: degradation, biodiversity, Sundarban, and Bangladesh. By considering the scope, 28 articles and 17 reports were incorporated to satisfy the objectives. The study revealed that the prominent causes of biodiversity loss of Sundarban might be due to intensified shrimp cultivation, increased dependency on forest and illicit felling, changing land use pattern, oil spillage, and pollution, forest fire, improper management practices, plant diseases, tourism activities, upstream withdrawal of river water, salinity intrusion, climate change, and some natural causes. The impacts were the loss of diversity of floral and faunal species subjected to regionally extinct, critically endangered, endangered, vulnerable, near threatened, and least concern condition. Occupational change and deterioration of the quality of life of surrounding communities are identified as impacts. Finally, the study recommended the formulation of a special mangrove forest policy and proper management practices of Sundarban with several environmental protection strategies that should be adopted to conserve this unique ecosystem.
The Rights of Nursing Mothers at the Workplace in the Perspective of Public Service and Its Effect on Job Performance
Authors: Astuti Sri Juni Woro , Endarti Esa Wahyu 
Published: April 2021

<p>This study aimed to examine whether the rights of nursing mothers at work have been fulfilled from a public service perspective and how this will affect their job performance. Mother’s role determines the quality of the next generation that depends on the quality of education and health provided to her children from an early age. From a health aspect, a mother must provide adequate nutrition from an early age through breast milk. Based on WHO recommendations, the Indonesian government recommends mothers to exclusively breastfeed for six months. From a legal aspect, the Indonesian government has provided protection rights for nursing mothers, as regulated in Law Number 13 of 2003 concerning Manpower. However, the phenomenon shows that more working mothers leave their children without breast milk and rely on their babies' nutrition from canned milk. This study uses a mixed methods. The population is female workers who have babies between 1 and 6 months age. Sample determined by a convenience method. Collecting data using questionnaires, interviews and secondary data. A total of 176 respondents have meet the criteria. In addition, we entered secondary data through digital document tracing. Data analysis was descriptive and triangulated with secondary data, then analyzed interactively to conclude. The results showed that the rights of mothers to breastfeed exclusively at work for 6 months have not been fulfilled properly. This finding supports the results of previous studies where adequate quality of care for nursing mothers will contribute to the performance of nursing mothers in the workplace.</p>
L-concave derived internal relations and L-convex derived enclosed relations
Authors: Wu X.Y. , Li E.Q. 
Published: May 2021

Abstract
Derived operator plays an important role in describing algebraic properties of many mathematical structures such as topology, matroid, convergence and convex space. In this paper, we present the notions of L-concave derived internal relation space and L-convex derived enclosed relation space by which we characterize L-concave space and L-convex space. Based on this, we further introduce some other structures such as L-concave derived hull space and L-convex derived hull space. We find that these spaces are isomorphic to L-concave space and L-convex space.
Freshwater alga Raphidocelis subcapitata undergoes metabolomic changes in response to electrostatic adhesion by micrometer-sized nylon 6 particles
Authors: Murata Satomi Mizukami , Suzuki Yuji , Sakurai Kensuke , Yamashita Hiromasa 
Published: April 2021

Abstract
Nylon powders are a type of microplastic (MP) used in personal care products such as cosmetics and sunscreens. To determine the effects of nylon on freshwater microalgae, we investigated the effects of two types of micrometer-sized nylons, i.e., powdered nylon 6 (Ny6-P) and nylon 12 (Ny12), and four other micrometer-sized MPs, i.e., low-density polyethylene, polyethylene terephthalate, polystyrene, and ultra-high-molecular-weight polyethylene, on the microalga Raphidocelis subcapitata. The results showed that Ny6-P inhibited R. subcapitata growth more than the other MPs; R. subcapitata growth was inhibited by 54.2% with 6.25 mg/L Ny6-P compared with the control. Ny6-P in the culture media adhered R. subcapitata cells electrostatically, which disrupted growth and photosynthesis. Metabolomic analysis revealed that many metabolites related to the amino acid catabolic pathway and γ-glutamyl cycle were induced, which might reflect responses to avoid starvation and oxidative stress. Our study provides important information on the effects of Ny6-P on algae in freshwater environments.
Nutritional Status Alterations After Chimeric Antigen Receptor T Cell Therapy in Patients With Hematological Malignancies: A Retrospective Study
Authors: Ding Shuyi , Cai Lingxia , Jin Aiyun , Zhou Xiaoyu , Yan Jiali , Wang Linqin , Zhao Houli , Wang Tingting , Hu Yongxian 
Published: April 2021

Abstract
Purpose: The influence of innovative chimeric antigen receptor T cell (CAR-T) therapy for hematological malignancies on nutritional status remains unknown. Therefore, we aim to explore the alterations of nutritional status after CAR-T therapy in patients with hematological malignancies.Methods: We retrospectively collected the data of patients with acute leukemia (AL), lymphoma and multiple myeloma (MM), who underwent CAR-T therapy at our hospital from 2018 to 2020. The serum albumin, triglyceride and cholesterol before and 7, 14 and 21 days after CAR-T cells infusion were compared and analyzed.Result: A total of 117 patients were enrolled, consisting of 39 AL, 23 lymphoma and 55 MM patients. The baseline albumin, triglyceride and cholesterol were 37.43±5.08 mg/L, 1.63±0.74 mmol/L and 3.62±1.03 mmol/L, respectively. The lowest albumin level was found at 7 days after CAR-T infusion compared with baseline (P<0.001), while the levels of triglyceride increased at 14 and 21 days (P<0.001, P=0.036). The levels of cholesterol at 7, 14, 21 days after CAR-T infusion were lower than baseline (all P<0.05). Spearman correlation coefficient showed cytokine release syndrome grade was negatively correlated with the levels of albumin at 7 days and cholesterol at 21 days after CAR-T infusion (r=-0.353, P<0.001; r=-0.395, P=0.002).Conclusion: Serum albumin and total cholesterol concentration decreased at the lowest level 7 days after CAR-T cells infusion, while triglyceride increased at 14 and 21 days after infusion. The levels of albumin and total cholesterol after CAR-T cells infusion were negatively correlated with the grade of cytokine release syndrome.
Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of human esophageal cancer
Authors: Song Libing , Wang Meng , Li Yue , Xiao Yunyun , Yang Muwen , Jian Yunting , Shi Dongni , Chen Xiangfu , Ouyang Ying , Kong Lingzhi , Huang Xinjian , Bai Jiewen , Lin Chuyong 
Published: April 2021

Abstract
Nicotine addiction and the occurrence of lymph node spread are two major significant factors associated with esophageal cancer's poor prognosis; however, nicotine's role in inducing lymphatic metastasis of esophageal cancer remains unclear. Here we showed that OTU domain-containing protein 3 (OTUD3) was downregulated by nicotine and correlated with poor prognosis in heavy-smoking esophageal cancer patients. Nicotine-mediated OTUD3 downregulation promoted lymphatic metastasis by inducing substantial tumor-induced lymphangiogenesis. At the mechanistic level, OTUD3 directly interacted with ZFP36 ring finger protein (ZFP36) and stabilized it by inhibiting FBXW7-mediated K48-linked polyubiquitination. ZFP36 bound with the VEGF-C 3-'UTR and recruited the RNA degrading complex to induce its rapid mRNA decay. Thus, downregulation of OTUD3 and ZFP36 was essential for nicotine-induced VEGF-C production and lymphatic metastasis in esophageal cancer. This study establishes that the OTUD3/ZFP36/VEGF-C axis plays a vital role in nicotine addiction-induced lymphatic metastasis. It also suggests that OTUD3 may serve as a prognostic marker, and induction of the VEGF-C mRNA decay might be a potential therapeutic strategy against human esophageal cancer.