bluuebunny/crossref_metadata_2025_split huggingface dataset:
Basic concept and clinical applications of quantitative ultrasound (QUS) technologies
Authors: Yamaguchi Tadashi 
Published: October 2021

AbstractIn the field of clinical ultrasound, the full digitalization of diagnostic equipment in the 2000s enabled the technological development of quantitative ultrasound (QUS), followed by multiple diagnostic technologies that have been put into practical use in recent years. In QUS, tissue characteristics are quantified and parameters are calculated by analyzing the radiofrequency (RF) echo signals returning to the transducer. However, the physical properties (and pathological level structure) of the biological tissues responsible for the imaging features and QUS parameters have not been sufficiently verified as there are various conditions for observing living tissue with ultrasound and inevitable discrepancies between theoretical and actual measurements. A major issue of QUS in clinical application is that the evaluation results depend on the acquisition conditions of the RF echo signal as the source of the image information, and also vary according to the model of the diagnostic device. In this paper, typical examples of QUS techniques for evaluating attenuation, speed of sound, amplitude envelope characteristics, and backscatter coefficient in living tissues are introduced. Exemplary basic research and clinical applications related to these technologies, and initiatives currently being undertaken to establish the QUS method as a true tissue characterization technology, are also discussed.
Fracture toughness as an alternative approach to quantify the ageing of insulation paper in oil
Authors: Fernández-Diego C. , Carrascal I. A. , Ortiz A. , Fernández I. , Ferreño D. , Diego S. , Casado A. 
Published: October 2021

AbstractOil-immersed transformers use paper and oil as insulation system which degrades slowly during the operation of these machines. Cellulose materials are used generally as insulation solid in power transformers. The degree of polymerization (DP), defined as number of repeating β-glucose residues in the cellulose molecule, is a critical property of cellulosic insulation material used in transformers, since it provides information about paper ageing and its mechanical strength. The fast-developing electric power industry demanding superior performance of electrical insulation materials has led to the development of new materials, as well as different drying techniques performed during transformer manufacturing and service when required. Both developments have caused some practical difficulties in the DP measurement. Moreover, the increasing interest in synthetic dielectric materials replacing cellulose materials requires measuring alternative properties to the DP to quantify the degradation of insulation solids over time. In this sense, this paper proposes the possibility of analyzing paper degradation through fracture toughness. This approach is different from the study of mechanical properties such as tensile strength or strain because it provides a tool for solving most practical problems in engineering mechanics, such as safety and life expectancy estimation of cracked structures and components which cannot to be considered through the traditional assessment of the mechanical resistance of the material. An accelerated thermal ageing of Kraft paper in mineral oil was carried out at 130 °C during different periods of time, to obtain information on the kinetics of the ageing degradation of the paper. Double-edged notched specimens were tested in tension to study their fracture toughness. The evolution of the load–displacement curves obtained for different ageing times at the ageing temperature of 130 °C was utilized to the determination of the stress intensity factor. Furthermore, different kinetic models based on this stress intensity factor were applied to relate its evolution over time as a function of the temperature. Finally, the correlation between the DP and stress intensity factor, which depends on the fiber angle, was also defined.
Graphic abstract
Implicit Attitudes Towards Weight, One’s Own Body and its Relation to Food in Women with Overweight and Obesity
Authors: Baur Julia , Schmitz Florian , Naumann Eva , Svaldi Jennifer 
Published: October 2021

Abstract
Background
Theoretical models emphasize the importance of implicit self-related weight attitudes for the maintenance of body dissatisfaction. Even though body dissatisfaction is increased in obesity, only general implicit weight-related attitudes have been investigated so far. Therefore, the present study assessed self-related and general implicit weight attitudes and their relation to food.

Methods
Women with overweight and obesity (OW; n = 71) and women with normal weight (NW; n = 44) completed three implicit tasks to (1) assess attitudes towards persons with normal weight and overweight in general, (2) attitudes towards one’s own body, and (3) the association between one’s own body and food.

Results
While both groups showed an implicit preference towards persons with normal weight relative to persons with overweight, only women with OW showed a significantly stronger negative implicit attitude towards their own body and a stronger association between food and one’s own body. Additionally, self-related and not general implicit weight attitudes correlated significantly with body dissatisfaction and eating pathology.

Conclusions
The results highlight the importance of self-related implicit attitudes and their relation to body dissatisfaction and eating pathology in women with overweight and obesity. Targeting these self-related implicit weight attitudes might help to improve obesity treatments.
SARS-CoV-2 Vaccine Induced Atypical Immune Responses in Antibody Defects: Everybody Does their Best
Authors: Salinas Ane Fernandez , Mortari Eva Piano , Terreri Sara , Quintarelli Concetta , Pulvirenti Federica , Di Cecca Stefano , Guercio Marika , Milito Cinzia , Bonanni Livia , Auria Stefania , Romaggioli Laura , Cusano Giuseppina , Albano Christian , Zaffina Salvatore , Perno Carlo Federico , Spadaro Giuseppe , Locatelli Franco , Carsetti Rita , Quinti Isabella 
Published: October 2021

Abstract
Background
Data on immune responses to SARS-CoV-2 in patients with Primary Antibody Deficiencies (PAD) are limited to infected patients and to heterogeneous cohorts after immunization.

Methods
Forty-one patients with Common Variable Immune Deficiencies (CVID), six patients with X-linked Agammaglobulinemia (XLA), and 28 healthy age-matched controls (HD) were analyzed for anti-Spike and anti-receptor binding domain (RBD) antibody production, generation of Spike-specific memory B-cells, and Spike-specific T-cells before vaccination and one week after the second dose of BNT162b2 vaccine.

Results
The vaccine induced Spike-specific IgG and IgA antibody responses in all HD and in 20% of SARS-CoV-2 naive CVID patients. Anti-Spike IgG were detectable before vaccination in 4 out 7 CVID previously infected with SARS-CoV-2 and were boosted in six out of seven patients by the subsequent immunization raising higher levels than patients naïve to infection. While HD generated Spike-specific memory B-cells, and RBD-specific B-cells, CVID generated Spike-specific atypical B-cells, while RBD-specific B-cells were undetectable in all patients, indicating the incapability to generate this new specificity. Specific T-cell responses were evident in all HD and defective in 30% of CVID. All but one patient with XLA responded by specific T-cell only.

Conclusion
In PAD patients, early atypical immune responses after BNT162b2 immunization occurred, possibly by extra-follicular or incomplete germinal center reactions. If these responses to vaccination might result in a partial protection from infection or reinfection is now unknown. Our data suggests that SARS-CoV-2 infection more effectively primes the immune response than the immunization alone, possibly suggesting the need for a third vaccine dose for patients not previously infected.
The wealth-consumption channel: evidence from a panel of Spanish households
Authors: Trivin Pedro 
Published: October 2021

AbstractIn this paper, we use a panel of Spanish households spanning the period 2002–2011 to study the marginal propensity to consume (MPC) out of wealth. The wealth effect is identified by exploiting within-household variations in a period of relatively large volatility in asset prices. We estimate a MPC out of total wealth of around 1 cent with changes in housing wealth affecting consumption more than other assets. We also find supporting evidence on the concavity of the consumption function, showing that the MPC decreases with net wealth. Our results uncover the existence of sign and magnitude asymmetries in the MPC. This asymmetric behavior is not present in households with higher income expectations, suggesting that the transmission channel is related to precautionary saving motives.
Efficacy of medication therapy for patients with chronic kidney disease and heart failure with preserved ejection fraction: a systematic review and meta-analysis
Authors: Yang Lei , Ye Nan , Bian Weijing , Cheng Hong 
Published: October 2021

Abstract
Background
The prevalence and mortality of heart failure with preserved ejection fraction (HFpEF) are high in patients with chronic kidney disease (CKD). However, there is still a lack of recommendations for the medication therapy of these patients in the guideline so far.

Methods
We conducted a systematic review and meta-analysis of all the studies assessing medication therapy for patients with CKD and HFpEF by July 21, 2021. Pooled analysis was performed using a random-effect model and the quality assessment was performed. In our research, we followed to the Preferred Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The meta-analysis was registered on PROSPERO.

Results
We finally identified six studies, three of which were randomized controlled trials and the others were retrospective cohort studies. The results of meta-analysis including three retrospective cohort studies showed that renin–angiotensin system inhibitors had significantly reduced all-cause mortality by 14% (3 studies, 3816 patients, HR 0.86; 95% CI 0.79–0.95; I2 = 49%; P = 0.003), and all-cause hospitalization by 11% (2 studies, 2350 patients, HR 0.89; 95% CI 0.85–0.94; I2 = 0%; P < 0.00001) in patients with CKD and HFpEF. However, there was no significant reduction in the risk of hospitalization for heart failure (3 studies, 3816 patients, HR 0.88; 95% CI 0.75–1.04; I2 = 75%; P = 0.13). One of the studies focused on the sacubitril–valsartan showed that sacubitril–valsartan was associated with a reduced risk of hospitalization for heart failure and cardiovascular death (RR 0.79, 95% CI 0.66–0.95). The study focused on the carvedilol did not show a significant reduction in the risk of hospitalization for heart failure and cardiovascular death (HR 0.917, 95% CI 0.501–1.678).

Conclusions
For patients with CKD and HFpEF, renin–angiotensin system inhibitors is associated with significant benefits in all-cause mortality and all-cause hospitalization but has no significant effect on hospitalization for heart failure. The subgroup analysis of one RCT study focused on ARNI showed that although long-term treatment with sacubitril–valsartan may reduce the risk of hospitalization for heart failure and cardiovascular death, more studies are needed to confirm that.
Experimental investigation of a rotor blade tip vortex pair
Authors: Schröder Dominic , Aguilar-Cabello Jorge , Leweke Thomas , Hörnschemeyer Ralf , Stumpf Eike 
Published: October 2021

AbstractThis paper presents the results of an experimental study of two closely spaced vortices generated by a rotating blade with a modified tip geometry. The experiments are carried out in two water channel facilities and involve a generic one-bladed rotor operating in a regime near hover. It is equipped with a parametric fin placed perpendicular to the pressure surface near the tip, which generates a co-rotating vortex pair having a helical geometry. Based on previous results obtained with a fixed wing, a series of small-scale experiments is first carried out, to validate the method of vortex pair generation also for a rotating blade, and to obtain a qualitative overview of its evolution going downstream. A more detailed quantitative study is then performed in a larger facility at three times the initial scale. By varying the fin parameters, it was possible to obtain a configuration in which the two vortices have almost the same circulation. In both experiments, the vortex pair is found to merge into a single helical wake vortex within one blade rotation. Particle image velocimetry measurements show that the resulting vortex has a significantly larger core radius than the single tip vortex from a blade without fin. This finding may have relevance in the context of blade–vortex interactions, where noise generation and fatigue from fluid–structure interactions depend strongly on the vortex core size.
Deep-Space Optical Navigation for M-ARGO Mission
Authors: Franzese V. , Topputo F. , Ankersen F. , Walker R. 
Published: October 2021

AbstractThe Miniaturised Asteroid Remote Geophysical Observer (M-ARGO) mission is designed to be ESA’s first stand-alone CubeSat to independently travel in deep space with its own electric propulsion and direct-to-Earth communication systems in order to rendezvous with a near-Earth asteroid. Deep-space Cubesats are appealing owing to the scaled mission costs. However, the operational costs are comparable to those of traditional missions if ground-based orbit determination is employed. Thus, autonomous navigation methods are required to favour an overall scaling of the mission cost for deep-space CubeSats. M-ARGO is assumed to perform an autonomous navigation experiment during the deep-space cruise phase. This paper elaborates on the deep-space navigation experiment exploiting the line-of-sight directions to visible beacons in the Solar System. The aim is to assess the experiment feasibility and to quantify the performances of the method. Results indicate feasibility of the autonomous navigation for M-ARGO with a 3σ accuracy in the order of 1000 km for the position components and 1 m/s for the velocity components in good observation conditions, utilising miniaturized optical sensors.
Preserving the Public Domain: Limits on Overlapping Copyright and Trade Secret Protection of Software
Authors: Mylly Ulla-Maija 
Published: October 2021

AbstractThe traditional understanding of intellectual property (IP) suggests that each IP category has a discrete subject matter of its own and exceptions thereto. Based on such an understanding of IP law, one would assume that there would not be overlapping IP protection for the same subject matter or product features. However, this understanding does not hold water. It has been argued that the development of overlapping IP rights has intensified as the subject matter that can be protected has expanded through the introduction of new rights and as the scope of protection for existing rights has increased. What may be particularly problematic is that, when policymakers focus on one IP regime at time, any issues arising from IP overlaps may remain undetected. For quite some time, there has been a policy tendency towards broadening the scope of intellectual property protection, which has led to a decrease in scope for the public domain. This tendency shows that the value of the public domain has not been appropriately identified or at the least not appreciated. One way to define the public domain is as the sphere that is not protected by any form of IP. This article will focus on the overlaps created by the Software Copyright and Trade Secrets Directives with regard to the protection of software. The ultimate aim of the article is to query whether the combined effects of these two Directives could be interpreted in a way that limits the undesirable expansion of protection.
Gynécomastie en pratique clinique pour les urologues
Authors: Blanc Julien , Roth Beat , Rakauskas Arnas 
Published: October 2021

RésuméLa gynécomastie est fréquemment retrouvée dans la pratique clinique de l’urologue ou du médecin généraliste. D’un point de vue physiopathologique, elle résulte d’un déséquilibre entre la concentration des œstrogènes et des androgènes. De multiples pathologies et traitements peuvent amener à cette perte d’équilibre. Il est important pour le clinicien de reconnaitre les signes de danger qui doivent faire suspecter une néoplasie maligne primaire du tissus mammaire ou secondaire ayant amené à la gynécomastie. Un bilan biologique de base permet le plus souvent de trouver la cause de la gynécomastie. Le traitement est le plus souvent sa cause. Pour certain cas particulier un traitement par le tamoxifène ou la radiothérapie peut être proposé. La chirurgie intervient lors de l’échec du traitement conservateur.
A novel IoT sensor authentication using HaLo extraction method and memory chip variability
Authors: Gordon Holden , Lyp Thomas , Kimbro Calvin , Tehranipoor Sara 
Published: October 2021

AbstractSince the inception of encrypted messages thousands of years ago, mathematicians and scientists have continued to improve encryption algorithms in order to create more secure means of communication. These improvements came by means of more complex encryption algorithms that have stronger security features such as larger keys and trusted third parties. While many new processors can handle these more complex encryption algorithms, IoT devices on the edge often struggle to keep up with resource intensive encryption standards. In order to meet this demand for lightweight, secure encryption on the edge, this paper proposes a novel solution, called the High and Low (HaLo) method, that generates Physical Unclonable Function (PUF) signatures based on process variations within flash memory. These PUF signatures can be used to uniquely identify and authenticate remote sensors, and help ensure that messages being sent from remote sensors are encrypted adequately without requiring computationally expensive methods. The HaLo method consumes 20x less power than conventional authentication schemes commonly used with IoT devices, it has an average latency of only 39ms for 512 bit signature generation, and the average error rate is below 0.06%. Due to its low latency, low error rate, and high power efficiency, the HaLo method can progress the field of IoT encryption standards by accurately and efficiently authenticating remote sensors without sacrificing encryption integrity.
Length of Stay and Home Discharge for Patients with Inpatient Stroke Rehabilitation
Authors: Tran Dat T. , Yan Charles , Dukelow Sean P. , Round Jeff 
Published: October 2021

Abstract:Objective:To examine temporal trends and geographic variations and predict inpatient rehabilitation (IPR) length of stay (LOS) and home discharge for stroke patients.Methods:Patients aged ≥18 years who were admitted to an IPR facility in Alberta, Canada, between 04/2014 and 03/2018 (years 2014–2017) were included. Predictors of LOS and home discharge were examined using 2014–2016 data and validated using 2017 data. Multivariable linear regression (MLR), multivariable negative binomial (MNB), and multivariable quantile regressions (MQR) were used to examine LOS, and logistic regression was used for home discharge.Results:We included 2686 rehabilitation admissions between 2014 and 2017. The mean LOS decreased (2014: 71 days; 2017: 62.1 days; p = 0.003) during the study period and was shortest in Edmonton (59.1 days) compared to Calgary (66 days) or other localities (70.8 days; p < 0.001). Three-quarters of patients were discharged home and this proportion remained unchanged between 2014 and 2017. Calgary patients were more likely to be discharged home than those in Edmonton (OR = 0.62; p = 0.019) or other localities (OR = 0.39; p = 0.011). The MLR and MNB models provided accurate prediction for the mean LOS (predicted = 59.9 and 60.8 days, respectively, vs. actual = 62.1 days; both p > 0.5), while the MQR model did so for the median LOS (predicted = 44.3 days vs. actual = 44 days; p = 0.09). The logistic regression resulted in 82.4% of correct prediction, a sensitivity of 91.6%, and a specificity of 50.7% for home discharge.Conclusions:Rehabilitation LOS decreased while the proportion of home discharge remained unchanged during the study period. Both varied across health zones. Identifiable statistical models provided accurate prediction with a separate patient cohort.
Packing topological entropy for amenable group actions
Authors: DOU DOU , ZHENG DONGMEI , ZHOU XIAOMIN 
Published: October 2021

AbstractPacking topological entropy is a dynamical analogy of the packing dimension, which can be viewed as a counterpart of Bowen topological entropy. In the present paper we give a systematic study of the packing topological entropy for a continuous G-action dynamical system
$(X,G)$
, where X is a compact metric space and G is a countable infinite discrete amenable group. We first prove a variational principle for amenable packing topological entropy: for any Borel subset Z of X, the packing topological entropy of Z equals the supremum of upper local entropy over all Borel probability measures for which the subset Z has full measure. Then we obtain an entropy inequality concerning amenable packing entropy. Finally, we show that the packing topological entropy of the set of generic points for any invariant Borel probability measure
$\mu $
coincides with the metric entropy if either
$\mu $
is ergodic or the system satisfies a kind of specification property.
No Excuses: A Brief History of Playing Through Risk in College Football
Authors: Bachynski Kathleen 
Published: October 2021

AbstractCelebrations of playing through risk, skepticism of athletes perceived as faking injuries, unregulated training regimens, the mythos of amateurism, and lack of accountability for preventable health harms have long characterized many college football programs. Setting policies that effectively prioritize player health will require taking this history into account.
THE IMPACT OF ORTHOGRAPHY ON LEXICAL ACCESS
Authors: Opitz Andreas , Bordag Denisa 
Published: October 2021

AbstractPrevious research has shown that orthographic marking may have a function beyond identifying orthographic word forms. In two visual priming experiments with native speakers and advanced learners of German (Czech natives) we tested the hypothesis that orthography can convey word-class cues comparable to morphological marking. We examined the effect of initial letter capitalization of nouns (a specific property of German orthography) on the processing of five homonymous and grammatically ambiguous forms. Both populations showed the same pattern of results: deverbal nouns (conversions) patterned together with countable nouns while in a previous study (with eliminated orthographic word-class cues) they patterned together with infinitives. Together, findings suggest that orthographic cues can trigger word-class-specific lexical retrieval/access. They also suggest a lexical entry structure in which conversion nouns, infinitives, and inflected verbal forms share a category-neutral parent node and that specified subnodes are accessed only when specifying cues are available and/or necessary for processing.