bluuebunny/crossref_metadata_2025_split huggingface dataset:
A VR-based approach in conducting MTM for manual workplaces
Authors: Gorobets Valentina , Holzwarth Valentin , Hirt Christian , Jufer Noëlle , Kunz Andreas 
Published: June 2021

AbstractDue to current trends in the manufacturing industry, such as mass customization, manual operations contribute drastically to the overall costs of a product. Methods-Time-Measurement (MTM) identifies the optimization potential of manual workplaces, which significantly influences a worker’s productivity. However, traditional MTM requires great efforts to observe and transcribe manual assembly processes. Yet, various digital approaches exist that facilitate MTM analyses. While most of these approaches require the existence of real workplaces or cardboard mock-ups, it would be beneficial to conduct a virtual MTM in earlier phases of production planning. However, the quality of virtual MTM analyses compared to traditional MTM conducted in reality has not been assessed yet. This paper is addressing it by conducting a comparative user study with 21 participants completing the same task both at a real and virtual workplace, which they access via virtual reality technology. Our results show that participants’ MTM-2 values achieved at the VR workplace are comparable to those at the real workplace. However, time study data reveals that participants moved considerably slower in VR and thus needed more time to accomplish the task. Consequently, for the measurement of manual work in VR, it is even necessary to utilize predetermined times, such as MTM-2 since time study data is insufficient. This paper also serves as a proof of concept for future studies, investigating automated transcription systems that would further decrease the efforts conducting MTM analyses.
How molecular imaging will enable robotic precision surgery
Authors: Wendler Thomas , van Leeuwen Fijs W. B. , Navab Nassir , van Oosterom Matthias N. 
Published: June 2021

AbstractMolecular imaging is one of the pillars of precision surgery. Its applications range from early diagnostics to therapy planning, execution, and the accurate assessment of outcomes. In particular, molecular imaging solutions are in high demand in minimally invasive surgical strategies, such as the substantially increasing field of robotic surgery. This review aims at connecting the molecular imaging and nuclear medicine community to the rapidly expanding armory of surgical medical devices. Such devices entail technologies ranging from artificial intelligence and computer-aided visualization technologies (software) to innovative molecular imaging modalities and surgical navigation (hardware). We discuss technologies based on their role at different steps of the surgical workflow, i.e., from surgical decision and planning, over to target localization and excision guidance, all the way to (back table) surgical verification. This provides a glimpse of how innovations from the technology fields can realize an exciting future for the molecular imaging and surgery communities.
TROPHY registry — status report
Authors: Thomale U. W. , Auer C. , Spennato P. , Schaumann A. , Behrens P. , Gorelyshev S. , Bogoslovskaia E. , Shulaev A. , Kabanian A. , Seliverstov A. , Alexeev A. , Ozgural O. , Kahilogullari G. , Schuhmann M. , Jimenez-Guerra R. , Wittayanakorn N. , Sukharev A. , Marquez-Rivas J. , Linsler S. , Damaty A. El , Vacek P. , Lovha M. , Guzman R. , Stricker S. , Beez T. , Wiegand C. , Azab M. , Buis D. , Sáez M. , Fleck S. , Dziugan C. , Ferreira A. , Radovnicky T. , Bührer C. , Lam S. , Sgouros S. , Roth J. , Constantini S. , Cavalheiro S. , Cinalli G. , Kulkarni A. V. , Bock H. C. 
Published: June 2021

Abstract
Introduction
The TROPHY registry has been established to conduct an international multicenter prospective data collection on the surgical management of neonatal intraventricular hemorrhage (IVH)-related hydrocephalus to possibly contribute to future guidelines. The registry allows comparing the techniques established to treat hydrocephalus, such as external ventricular drainage (EVD), ventricular access device (VAD), ventricular subgaleal shunt (VSGS), and neuroendoscopic lavage (NEL). This first status report of the registry presents the results of the standard of care survey of participating centers assessed upon online registration.

Methods
On the standard of treatment forms, each center indicated the institutional protocol of interventions performed for neonatal post-hemorrhagic hydrocephalus (nPHH) for a time period of 2 years (Y1 and Y2) before starting the active participation in the registry. In addition, the amount of patients enrolled so far and allocated to a treatment approach are reported.

Results
According to the standard of treatment forms completed by 56 registered centers, fewer EVDs (Y1 55% Y2 46%) were used while more centers have implemented NEL (Y1 39%; Y2 52%) to treat nPHH. VAD (Y1 66%; Y2 66%) and VSGS (Y1 42%; Y2 41%) were used at a consistent rate during the 2 years. The majority of the centers used at least two different techniques to treat nPHH (43%), while 27% used only one technique, 21% used three, and 7% used even four different techniques. Patient data of 110 infants treated surgically between 9/2018 and 2/2021 (13% EVD, 15% VAD, 30% VSGS, and 43% NEL) were contributed by 29 centers.

Conclusions
Our results emphasize the varying strategies used for the treatment of nPHH. The international TROPHY registry has entered into a phase of growing patient recruitment. Further evaluation will be performed and published according to the registry protocol.
Correlation analysis of resected breast tissue and implant volume after mastectomy and its association with breast density
Authors: Malter Wolfram , Bachmann Bo Jan , Krug Barbara , Hellmich Martin , Zinser Max , Mallmann Peter , Eichler Christian , Puppe Julian 
Published: June 2021

Abstract
Background
The current methods for calculating the ideal implant volume for breast reconstruction are based on pre- or intraoperative volume measurements of the existing breast volume and do not take into account the individual breast density of the woman. This study aims is to identify objective parameters that can help to improve the optimal implant selection.

Materials and methods
This retrospective analysis includes 198 breast cancer patients who underwent mastectomy. Breast densities (ACR) measured in mammography and MRI were compared with the removed breast tissue weight and volume of the implants used. In addition, the resected weight was compared directly with the implant volume to calculate a mathematical function.

Results
There was no significant correlation between the ACR values and the resected weights [correlation coefficient: mammography:− 0.117 (p = 0.176), MRI − 0.033 (p = 0.756)]. A negative correlation between the implant volumes and both imaging methods could be demonstrated [correlation coefficient: mammography − 0.268; p = 0.002; MRI was − 0.200 (p = 0.055)]. A highly significant correlation between the resected weights and the implant volumes (correlation coefficient 0.744; p < 0.001) was observed. This correlation corresponds to a power function (y = 34.71 x0.39), in which any resected weight can be used for the variable x to calculate the implant volume.

Conclusion
We were able to show that there is a significant correlation between the resected breast tissue and the implant volume. With our novel potency function, the appropriate implant volume can be calculated for any resected weight making it easier for the surgeon to choose a fitting implant in a simple and more objective manner.
The role of action effects in motor sequence planning and execution: exploring the influence of temporal and spatial effect anticipation
Authors: Brown Rachel M. , Friedgen Erik , Koch Iring 
Published: June 2021

AbstractActions we perform every day generate perceivable outcomes with both spatial and temporal features. According to the ideomotor principle, we plan our actions by anticipating the outcomes, but this principle does not directly address how sequential movements are influenced by different outcomes. We examined how sequential action planning is influenced by the anticipation of temporal and spatial features of action outcomes. We further explored the influence of action sequence switching. Participants performed cued sequences of button presses that generated visual effects which were either spatially compatible or incompatible with the sequences, and the spatial effects appeared after a short or long delay. The sequence cues switched or repeated across trials, and the predictability of action sequence switches was varied across groups. The results showed a delay-anticipation effect for sequential action, whereby a shorter anticipated delay between action sequences and their outcomes speeded initiation and execution of the cued action sequences. Delay anticipation was increased by predictable action switching, but it was not strongly modified by the spatial compatibility of the action outcomes. The results extend previous demonstrations of delay anticipation to the context of sequential action. The temporal delay between actions and their outcomes appears to be retrieved for sequential planning and influences both the initiation and the execution of actions.
Dual variational methods for a nonlinear Helmholtz equation with sign-changing nonlinearity
Authors: Mandel Rainer , Scheider Dominic , Yeşil Tolga 
Published: June 2021

AbstractWe prove new existence results for a nonlinear Helmholtz equation with sign-changing nonlinearity of the form $$\begin{aligned} - \Delta u - k^{2}u = Q(x)|u|^{p-2}u, \quad u \in W^{2,p}\left( {\mathbb {R}}^{N}\right) \end{aligned}$$

-
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-

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=
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2

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,

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∈

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,
p

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with $$k>0,$$

k
>
0
,

$$N \ge 3$$

N
≥
3

, $$p \in \left[ \left. \frac{2(N+1)}{N-1},\frac{2N}{N-2}\right) \right. $$

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∈

2
(
N
+
1
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,

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-
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and $$Q \in L^{\infty }({\mathbb {R}}^{N})$$

Q
∈

L
∞

(

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. Due to the sign-changes of Q, our solutions have infinite Morse-Index in the corresponding dual variational formulation.
On the Flame Shape in a Premixed Swirl Stabilised Burner and its Dependence on the Laminar Flame Speed
Authors: Papafilippou Nikolaos , Chishty Muhammad Aqib , Gebart Rikard 
Published: June 2021

AbstractGas turbines for power generation are optimised to run with fossil fuels but as a response to tighter pollutant regulations and to enable the use of renewable fuels there is a great interest in improving fuel flexibility. One interesting renewable fuel is syngas from biomass gasification but its properties vary depending on the feedstock and gasification principle, and are significantly different from conventional fuels. This paper aims to give an overview of the differences in combustion behaviour by comparing numerical solutions with methane and several different synthesis gas compositions. The TECFLAM swirl burner geometry, which is designed to be representative of common gas turbine burners, was selected for comparison. The advantage with this geometry is that detailed experimental measurements with methane are publicly available. A two-stage approach was employed with development and validation of an advanced CFD model against experimental data for methane combustion followed by simulations with four syngas mixtures. The validated model was used to compare the flame shape and other characteristics of the flow between methane, 40% hydrogen enriched methane and four typical syngas compositions. It was found that the syngas cases experience lower swirl intensity due to high axial velocities that weakens the inner recirculation zone. Moreover, the higher laminar flame speed of the syngas cases has a strong effect on the flame front shape by bending it away from the axial direction, by making it shorter and by increasing the curvature of the flame front. A hypothesis that the flame shape and position is primarily governed by the laminar flame speed is supported by the almost identical flame shapes for bark powder syngas and 40% hydrogen enriched methane. These gas mixtures have almost identical laminar flame speeds for the relevant equivalence ratios but the heating value of the syngas is more than a factor of 3 smaller than that of the hydrogen enriched methane. The syngas compositions used are representative of practical gasification processes and biomass feedstocks. The demonstrated strong correlation between laminar flame speed and flame shape could be used as a rule of thumb to quickly judge whether the flame might come in contact with the structure or in other ways be detrimental to the function of the combustion system.
Displacement-based design of precast hinged portal frames with additional dissipating devices at beam-to-column joints
Authors: Belleri Andrea , Labò Simone 
Published: June 2021

AbstractThe seismic performance of precast portal frames typical of the industrial and commercial sector could be generally improved by providing additional mechanical devices at the beam-to-column joint. Such devices could provide an additional degree of fixity and energy dissipation in a joint generally characterized by a dry hinged connection, adopted to speed-up the construction phase. Another advantage of placing additional devices at the beam-to-column joint is the possibility to act as a fuse, concentrating the seismic damage on few sacrificial and replaceable elements. A procedure to design precast portal frames adopting additional devices is provided herein. The procedure moves from the Displacement-Based Design methodology proposed by M.J.N. Priestley, and it is applicable for both the design of new structures and the retrofit of existing ones. After the derivation of the required analytical formulations, the procedure is applied to select the additional devices for a new and an existing structural system. The validation through non-linear time history analyses allows to highlight the advantages and drawbacks of the considered devices and to prove the effectiveness of the proposed design procedure.
Delayed improvement local search
Authors: Amaral Heber F. , Urrutia Sebastián , Hvattum Lars M. 
Published: June 2021

AbstractLocal search is a fundamental tool in the development of heuristic algorithms. A neighborhood operator takes a current solution and returns a set of similar solutions, denoted as neighbors. In best improvement local search, the best of the neighboring solutions replaces the current solution in each iteration. On the other hand, in first improvement local search, the neighborhood is only explored until any improving solution is found, which then replaces the current solution. In this work we propose a new strategy for local search that attempts to avoid low-quality local optima by selecting in each iteration the improving neighbor that has the fewest possible attributes in common with local optima. To this end, it uses inequalities previously used as optimality cuts in the context of integer linear programming. The novel method, referred to as delayed improvement local search, is implemented and evaluated using the travelling salesman problem with the 2-opt neighborhood and the max-cut problem with the 1-flip neighborhood as test cases. Computational results show that the new strategy, while slower, obtains better local optima compared to the traditional local search strategies. The comparison is favourable to the new strategy in experiments with fixed computation time or with a fixed target.
Inscriptions and Images in Secular Buildings: Examples from Renaissance Scania, Sweden, ca. 1450–1658
Authors: Hansson Martin 
Published: June 2021

AbstractThis paper examines how agents inscribed their persona in buildings during the Renaissance in Scania in present-day Sweden. Through an analysis of stone tablets and timber beams with inscriptions, images, and dates, questions of identity and individuality are highlighted. The objects were often placed above doors in noble country residences or in buildings belonging to the urban elite. The paper discusses who was able to see and understand the messages communicated by the buildings, and when, how, and why the tradition of putting up this type of object on buildings emerged in a Scandinavian context.
Power struggles in policy feedback processes: incremental steps towards a circular economy within Dutch wastewater policy
Authors: Ampe Kasper , Paredis Erik , Asveld Lotte , Osseweijer Patricia , Block Thomas 
Published: June 2021

AbstractEnvironmental problems are usually not tackled with path-departing policies but rather with incrementally adjusted or unchanged policies. One way to address incremental change is the policy feedback approach, which initially focussed on self-reinforcing feedback and path-dependency. Today, self-undermining feedback is also increasingly being studied, centring on agency and change. However, it is unclear precisely how actors use power in policy feedback processes. Therefore, this study applied a power perspective and the policy arrangement approach to a case study of the reorientation towards a circular economy in Dutch wastewater policy between 2008 and 2018, which resulted in incremental instead of fundamental policy change. Here it was observed that self-undermining feedback was generated from 2008 onwards but the balance quickly shifted back to self-reinforcing feedback, indicating that the analysed power struggles led to incremental change. These dynamics resemble a shift from the so-called paths and forks (i.e. fork in the road) towards the boomerang pattern (i.e. returning to its original position) of policy change. The patterns are explained by focussing on powerful actors that resist change through the use of incremental reforms, the ongoing struggles of these actors in facilitating self-reinforcing feedback and the role of interpretation in using feedback as a resource. Overall, this study provides a nuanced understanding of incremental change by directing attention to the power struggles of actors in policy feedback processes. For practitioners, the study emphasises the importance of power struggles in enabling a circular economy.
Potential application and beneficial effects of a marine microalgal biomass produced in a high-rate algal pond (HRAP) in diets of European sea bass, Dicentrarchus labrax
Authors: Pascon Giulia , Messina Maria , Petit Lisa , Valente Luisa Maria Pinheiro , Oliveira Beatriz , Przybyla Cyrille , Dutto Gilbert , Tulli Francesca 
Published: June 2021

AbstractMicroalgae have been used as live food in aquatic species. In recent years, the interest in microalgae has considerably increased, thanks to the evolution of production techniques that have identified them as an ecologically attractive aquafeed ingredient. The present study provides the first data about the effects of dietary inclusion of a microalgae consortium grown in a high-rate algal pond system on zootechnical performance, morphometric indices, and dietary nutrient digestibility as well as morphology and functionality of the digestive system of European sea bass,Dicentrarchus labrax. A dietary treatment including a commercial mono-cultured microalgae (Nannochloropsissp.) biomass was used for comparison. Six hundred and thirty-six European sea bass juveniles (18 ± 0.28 g) were randomly allotted into 12 experimental groups and fed 4 different diets for 10 weeks: a control diet based on fish meal, fish oil, and plant protein sources; a diet including 10% ofNannochloropsisspp. biomass (100 g/kg diet); and two diets including two levels (10% and 20%) of the microalgal consortium (100 and 200 g/kg diet).Even at the highest dietary inclusion level, the microalgal consortium (200 g/kg diet) did not affect feed palatability and fish growth performance. A significant decrease in the apparent digestibility of dry matter, protein, and energy was observed in diets including 10 and 20% of the microalgal consortium, but all fish exhibited a well-preserved intestinal histomorphology. Moreover, dietary inclusion with the microalgal consortium significantly increased the enzymatic activity of maltase, sucrase-isomaltase, and ɤ-glutamil transpeptidase in the distal intestine of the treated European sea bass. Algal consortium grown using fish farm effluents represents an attempt to enhance the utilization of natural biomasses in aquafeeds when used at 10 % as substitute of vegetable ingredients in diet for European sea bass.
Particle shape does not affect ingestion and egestion of microplastics by the freshwater shrimp Neocaridina palmata
Authors: Klein Kristina , Heß Sebastian , Nungeß Sandra , Schulte-Oehlmann Ulrike , Oehlmann Jörg 
Published: June 2021

AbstractThe ingestion of microplastics (MPs) is well documented for various animals and spherical MPs (beads) in many studies. However, the retention time and egestion of MPs have been examined less, especially for irregular MPs (fragments) which are predominantly found in the environment. Furthermore, the accumulation of such particles in the gastrointestinal tract is likely to determine whether adverse effects are induced. To address this, we investigated if the ingestion and egestion of beads are different to those of fragments in the freshwater shrimp Neocaridina palmata. Therefore, organisms were exposed to 20–20,000 particles L−1 of either polyethylene (PE) beads (41 μm and 87 μm) or polyvinyl chloride (PVC) fragments (<63 μm). Moreover, shrimps were exposed to 20,000 particles L−1 of either 41 μm PE and 11 μm polystyrene (PS) beads or the PVC fragments for 24 h, followed by a post-exposure period of 4 h to analyze the excretion of particles. To simulate natural conditions, an additional fragment ingestion study was performed in the presence of food. After each treatment, the shrimps were analyzed for retained or excreted particles. Our results demonstrate that the ingestion of beads and fragments were concentration-dependent. Shrimps egested 59% of beads and 18% of fragments within 4 h. Particle shape did not significantly affect MP ingestion or egestion, but size was a relevant factor. Medium- and small-sized beads were frequently ingested. Furthermore, fragment uptake decreased slightly when co-exposed to food, but was not significantly different to the treatments without food. Finally, the investigations highlight that the assessment of ingestion and egestion rates can help to clarify whether MPs remain in specific organisms and, thereby, become a potential health threat.
If One Can’t Lose Such a Right in These Circumstances, One Never Had It in the First Place
Authors: Otsuka Michael 
Published: June 2021

AbstractIn this article, I press a line of objection to Jonathan Quong's moral status account of liability to defensive harm. The claim on which I rest my critique is captured by the article's title: if one can’t lose such a right in these circumstances, one never had it in the first place.