bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accretion bursts in high-mass protostars: A new test bed for models of episodic accretion
Authors: Elbakyan Vardan G. , Nayakshin Sergei , Vorobyov Eduard I. , Caratti o Garatti Alessio , Eislöffel Jochen 
Published: June 2021

Aims. It is well known that low-mass young stellar objects (LMYSOs) gain a significant portion of their final mass through episodes of very rapid accretion, with mass accretion rates up to Ṁ∗ ∼ 10−4 M⊙ yr−1. Recent observations of high-mass young stellar objects (HMYSOs) with masses M∗ ≳ 10 M⊙ uncovered outbursts with accretion rates exceeding Ṁ∗ ∼ 10−3 M⊙ yr−1. Here, we examine which scenarios proposed in the literature so far to explain accretion bursts of LMYSOs can also apply to the episodic accretion in HMYSOs.
Methods. We utilise 1D time-dependent models of protoplanetary discs around HMYSOs to study burst properties.
Results. We find that discs around HMYSOs are much hotter than those around their low-mass cousins. As a result, a much more extended region of the disc is prone to the thermal hydrogen ionisation and magnetorotational activation instabilities. The former, in particular, is found to be ubiquitous in a very wide range of accretion rates and disc viscosity parameters. The outbursts triggered by these instabilities, however, always have too low of an Ṁ∗ and are one to several orders of magnitude too long compared to those observed from HMYSOs to date. On the other hand, bursts generated by tidal disruptions of gaseous giant planets formed by the gravitational instability of the protoplanetary discs yield properties commensurate with observations, provided that the clumps are in the post-collapse configuration with planet radius Rp ≳ 10 Jupiter radii. Furthermore, if observed bursts are caused by disc ionisation instabilities, then they should be periodic phenomena with the duration of the quiescent phase comparable to that of the bursts. This may yield potentially observable burst periodicity signatures in the jets, the outer disc, or the surrounding diffuse material of massive HMYSOs. Bursts produced by disruptions of planets or more massive objects are not expected to be periodic phenomena, although multiple bursts per protostar are possible.
Conclusions. Observations and modelling of episodic accretion bursts across a wide range of young stellar object (YSO) masses is a new promising avenue to break the degeneracy between models of episodic accretion in YSOs.
Calculation of the durability of sealing and awning materials
Authors: Koutsenko Timur , Shelihov Nikolay , Kutsenko Svetlana 
Published: June 2021

The article discusses the hypotheses for determining the equivalent laboratory modes for assessing the durability of sealing and awning materials, and evaluates the accuracy of the proposed method. Qualitative research of operational factors influence (UV, temperature) on sealing and awning materials durability was conducted. Purpose of the study: a method for predicting the durability of sealing and awning materials. Methods: Methods for fast assessment of durability and methods of equivalent factors. Results: Based on the obtained regularities of the behavior of sealing and awning materials under conditions of repeated loading and ultraviolet radiation, as well as the accepted hypotheses about the summation of damage and irreversibility of the destruction process, a laboratory test mode was determined that was equivalent in terms of the level of introduced destruction to the operating mode, including the action of multiple loads and ultraviolet radiation.
Based on the equivalent accelerated test mode and the characteristics of the operating mode of loading and irradiation, a method for assessing the durability of sealing and awning materials is proposed.
The equation of the oscillatory motion of the blade of the earth-moving machine depending on the properties of the ground and the parameters of the blade
Authors: Zemdikhanov Minsur , Sakhapov Rustem , Gainutdinov Ramil 
Published: June 2021

The influence of the design parameters and technological properties of the ground on the nature of the oscillatory movement of the blade of the working body of the earth-moving machine is investigated.
The purpose of the study is to identify the force factors of the interaction of the oscillatory working body of the earth-moving machine with the ground and determine its optimal parameters.
The equation of the oscillatory motion of the blade of the working body of the earthmoving machine depending on its design parameters and technological properties of the ground is obtained.
The results can be used in the development and determination of the optimal design parameters of the working bodies of earth-moving machines.
Hilfe für Haare
Authors: Gude Annette 
Published: June 2021

SummaryFür Haarausfall kann es aus westlicher medizinischer Sicht verschiedene Ursachen geben, zum Beispiel chronische Erkrankungen, erbliche Faktoren oder Medikamente. Die drei häufigsten Formen von Haarausfall sind androgenetischer Haarausfall, diffuser Haarausfall und kreisrunder Haarausfall. Aus Sicht der Traditionellen Chinesischen Medizin (TCM) ist bei Haarausfall insbesondere eine Yin- und Blutstärkung zentral.
Supplementieren – aber richtig
Authors: Feldhaus Simon 
Published: June 2021

SummaryOft ist auch bei ausgewogener Ernährung keine ausreichende Zufuhr aller wichtigen Mikronährstoffe möglich, wobei einige Bevölkerungsgruppen besonders gefährdet für Mängel sind. Sinnvoll ist, die Blutkonzentration von Mikronährstoffen vor Beginn einer Supplementierung zu ermitteln und diese regelmäßig im Behandlungsverlauf zu kontrollieren. Besonders häufig müssen Vitamin D, Omega-3-Fettsäuren, Folsäure, Magnesium, Eisen, Zink und Vitamin B12 in unseren Breitengraden supplementiert werden, um verschiedene Folgen von Mangelzuständen zu vermeiden.
Establishment of an In Vitro Co-Culture Model of the Piglet Gut to Study Inflammatory Response and Barrier Integrity
Authors: Schott Theresa , Reisinger Nicole , Teichmann Klaus , König Jürgen , Ladinig Andrea , Mayer Elisabeth 
Published: June 2021

AbstractIn intensive farming, piglets are exposed to various challenges that activate intestinal inflammatory processes, negatively affecting animal health and leading to economic losses. To study the role of the inflammatory response on epithelial barrier integrity, co-culture systems that mimic in vivo complexity are more and more preferred over cell monocultures. In this study, an in vitro gut co-culture model consisting of intestinal porcine epithelial cells and porcine peripheral blood mononuclear cells was established. The model provides an appropriate tool to study the role of the inflammatory response on epithelial barrier integrity and to screen for feed and food components, exerting beneficial effects on gut health. In the established model, inflammation-like reactions and damage of the epithelial barrier, indicated by a decrease of transepithelial electrical resistance, were elicited by activation of peripheral blood mononuclear cells via one of 3
stimuli: lipopolysaccharide, lipoteichoic acid, or concanavalin A. Two phytogenic substances that are commonly used as feed additives, licorice extract and oregano oil, have been shown to counteract the drop in transepithelial electrical resistance values in the gut co-culture model. The established co-culture model provides a powerful in vitro tool to study the role of intestinal inflammation on epithelial barrier integrity. As it consists of porcine epithelial and porcine blood cells it perfectly mimics in vivo conditions and imitates the inter-organ communication of the piglet gut. The developed model is useful to screen for nutritional components or drugs, having the potential to balance intestinal inflammation and strengthen the epithelial barrier integrity in piglets.
Biocompatibility Evaluation of Human and Porcine Acellular Dermal Matrix on Human Primary Gingival Fibroblasts: In Vitro Comparative Study
Authors: Azab Ehab , Youssef Abdel-Rahman 
Published: June 2021

AbstractObjective Allogeneic and xenogeneic acellular dermal matrix (ADM) grafts have been used to treat periodontal soft tissue defects. The purpose of the current study was to compare the effect of human ADM (AlloDerm) and porcine ADM (Derma) on human primary gingival fibroblasts in vitro regarding the biocompatibility test.Materials and Methods Gingival fibroblasts were obtained from healthy adult gingiva and seeded on AlloDerm or Derma ADM in 96-well plate. The control cells were grown on a surface-treated polystyrene cell-culture plate without matrix. The cells were cultured for 3, 7, and 14 days. The fibroblasts morphology was examined using inverted microscopy, and the cell viability of fibroblasts adherent to the dermal matrix was evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) cell viability assay after 3, 7, and 14 days in culture. The data were statistically evaluated by one-way analysis of variance. p-Value of 0.05 was considered significant.Results Gingival fibroblasts adjacent to the AlloDerm and Derma matrices were healthy, attached to the well, and did not exhibit any cytopathic changes similar to control. There were no statistically significant differences in the cell viability between the gingival fibroblasts attached to Derma and AlloDerm on day 3 (p = 0.841), day 7 (p = 0.198), and day 14 (p = 0.788).Conclusion Considering this in vitro study’s limitations, both human and porcine ADM were compatible with the surrounding human primary gingival fibroblasts. No significant differences were observed in the cell viability between the gingival fibroblasts that were attached to Derma and AlloDerm.
Supramolecular Thiophene-Based Materials: A Few Examples of the Interplay between Synthesis, Optoelectronic Properties and Applications
Authors: Di Maria Francesca , Zangoli Mattia , Barbarella Giovanna 
Published: June 2021

Supramolecular nanostructured thiophene based materials with optoelectronic functions are of wide current interest and are playing a crucial role in different fields of nanoscience and nanotechnology. This short review gives a concise report of some particularly interesting examples from our own work concerning thiophene-based supramolecular architectures at multiple length scales, their function and application in devices. We start with some general considerations on the great chemical diversity of thiophene derivatives and their supramolecular architectures. Then we focus on how the supramolecular organization of specific thiophene derivatives may generate nanostructures that enable new functions and applications in devices. For each example, we report the synthesis of the corresponding thiophene derivatives.1. Introduction2. Supramolecular Organization may Impart New Functions to the System3. Supramolecular and Optoelectronic Properties of Oligothiophene-S,S-dioxides4. Colloidal Nanoparticles formed by Self-Assembly of Thiophene-Based Polymers5. Conclusions and Outlook
Metallosis in Sequelae of Prosthetic Revision for Ceramic Components Fracture: A Case Report with Clinical Presentation Mimicking Periprosthetic Hip Infection
Authors: Artiaco Stefano , Fusini Federico , Zoccola Kristijan , Massè Alessandro , Colzani Giulia 
Published: June 2021

AbstractCeramic on ceramic total hip arthroplasties have been developed and widely used during last decades because of their long-term survival and biomechanical properties. One of the most dangerous complication of these implants is the fracture of the ceramic components. The management of this condition should be carefully planned and the choice of the new implant is crucial. We describe a rare case of severe hip synovitis due to massive metallosis in sequelae of mismanaged prosthetic revision for fracture of the ceramic acetabular liner with an unusual clinical presentation that simulate a periprosthetic infection.
Prospective Comparative Study of Preoperative Expectations and Postoperative Outcomes in Anatomic and Reverse Shoulder Arthroplasty
Authors: Lawrence Cassandra , Lazarus Mark , Abboud Joseph , Williams Gerald , Namdari Surena 
Published: June 2021

Abstract
Background Compared with anatomic total shoulder arthroplasty (aTSA), reverse total shoulder arthroplasty (RTSA) is associated with lower preoperative and postoperative outcome scores and range of motion. It is unknown whether patients' preoperative expectations of surgery are lower in RTSA compared with aTSA. The purpose of this study was to assess preoperative patient expectations and postoperative outcomes in aTSA and RTSA.
Methods A consecutive series of patients undergoing primary aTSA for diagnosis of osteoarthritis or primary RTSA for diagnosis of rotator cuff tear arthropathy were studied prospectively. Expectations were evaluated using the validated Hospital for Special Surgery's Shoulder Surgery Expectations Survey. Baseline demographics, comorbidities, and social factors were collected. Baseline and 2 years postoperative American Shoulder and Elbow Surgeons (ASES) score, visual analog scale pain, Single Assessment Number Evaluation (SANE), and patient satisfaction were obtained.
Results There were 128 patients (64 aTSA and 64 RTSA). There was no significant difference in total preoperative expectations score between groups. On multivariate linear regression analysis, aTSA (p = 0.024) and younger age (p = 0.018) were associated with higher expectations for improved ability to exercise. Changes in preoperative to postoperative ASES (p = 0.004) and SANE (p = 0.001) scores were higher in the aTSA group. Total preoperative expectations score was not correlated with postoperative functional outcomes or satisfaction in either group. In the aTSA group, expectations for participation in exercise were positively correlated with changes in preoperative to postoperative ASES score (p = 0.01) and SANE score (p = 0.01).
Conclusion Though patients undergoing primary aTSA demonstrated greater improvement in functional outcome than those undergoing primary RTSA, both groups reported similar aggregate preoperative expectations. Those undergoing aTSA had higher expectations for return to exercise which was positively correlated with postoperative functional outcomes.
Level of Evidence Level II, prospective cohort study.
FLT3 Gene Mutation in Acute Myeloid Leukemia: Correlation with Hematological, Immunophenotypic, and Cytogenetic Characteristics
Authors: Shankaralingappa Sunitha , Joshi Hemangi D. , Patel Jayendra B. , Patel Prabhudas , Sawhney Jyoti 
Published: June 2021

Introduction In acute myeloid leukemia (AML), FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) is a common driver mutation associated with high tumor burden and poor prognosis. This mutation is common in normal karyotype AML and such patients have high leukocyte count. The presence of this mutation can be predicted by certain hematological and immunophenotypic characteristics in day-to-day practice.
Objective This study was undertaken to assess the strength of association between FLT3 gene mutation and hematological and immunophenotypic characteristics.
Materials and Methods Morphological, hematological, immunophenotypic, and cytogenetic characteristics of FLT3 mutations recorded in 424 patients of AML in adults and children between 2016 and 2019 in a tertiary care cancer center in Western India. Blasts were classified according to French-American-British method. Tumor burden was assessed by serum lactate dehydrogenase (LDH) levels, leucocyte count, and peripheral smear blast percentage.
Results Out of 424 cases, FLT3-ITD and FLT3-tyrosine kinase domain mutation were found in 72 and 25 AML patients, respectively. Patients with FLT3 mutation had high tumor burden, characterized by high leukocyte count (p < 0.001), peripheral blood (p = 0.01) and bone marrow (p = 0.03) blast percentage, and high serum LDH (mean 777.8 vs. 586; p = 0.10) compared with FLT3-negative patients. They also featured high platelet count (p < 0.001). Morphological, immunophenotypic, and cytogenetic characteristics also have been presented in the study.
Conclusion Observations of the study suggest the presence of definitive hematological and immunophenotypic characteristics along with raised serum LDH levels serve as surrogate markers and indicators of FLT3 mutation in AML patients.
Public engagement with health data governance: the role of visuality
Authors: Sleigh Joanna , Vayena Effy 
Published: June 2021

AbstractOver the last years, public engagement has become a topic of scholarly and policy debate particularly in biomedicine, a field that increasingly centres around collecting, sharing and analysing personal data. However, the use of big data in biomedicine poses specific challenges related to gaining public support for health data usage in research and clinical settings. The improvement of public engagement practices in health data governance is widely recognised as critical to address this issue. Based on OECD guidance, public engagement serves to enhance transparency and accountability, and enable citizens to actively participate in shaping what affects their lives. For health research initiatives, this provides a way to cultivate cooperation and build public trust. Today, the exact formats of public engagement have evolved to include approaches (such as social media, events and websites) that exploit visualisation mediated by emerging information and communication technologies. Much scholarship acknowledges the advantages of visuality for public engagement, particularly in information-dense and digital contexts. However, little research has examined how health data governance actors utilise visuality to promote clarity, understandability and audience participation. Beyond simply acknowledging the diversity of possible formats, attention must also be paid to visualisations’ rhetorical capacity to convey arguments and ideas and motivate particular audiences in specific situations. This paper seeks to address this gap by analysing both the approaches and methods of argumentation used in two visual public engagement campaigns. Based on Gottweis’ analytical framework of argumentative performativity, this paper explores how two European public engagement facilitators construct contending narratives in efforts to make sense of and grapple with the challenges of health data sharing. Specifically, we analyse how their campaigns employ the three rhetorical elements logos, ethos and pathos, proposed by Gottweis to assess communicative practices, intermediated and embedded in symbolically rich social and cultural contexts. In doing so, we highlight how visual techniques of argumentation seek to bolster engagement but vary with rhetorical purposes, as while one points to health data sharing risks, the other focuses on benefits. Moreover, drawing on digital and visual anthropology, we reflect on how the digitalisation of communicative practices impacts visual power.
Charge–spin conversion in Pt1−xBix alloys for spin–orbit torque switching
Authors: Chi Zhendong , Lau Yong-Chang , Kawaguchi Masashi , Hayashi Masamitsu 
Published: June 2021

We have studied the spin torque efficiency of Pt1−xBix/Co based heterostructures for spin–orbit torque (SOT) switching devices. While the field-like component of the SOT shows a relatively small change with the Bi concentration (x), the damping-like component (ξDL) abruptly increases with increasing x. The increase in ξDL with x is largely associated with the change in the Pt1−xBix layer resistivity (ρxx). The spin Hall conductivity (σSH) estimated from ξDL and ρxx remains nearly constant at ∼830 (ℏ/e) Ω−1 cm−1 for 0 &lt; x ≲ 0.6. Further substitution of Bi results in the formation of PtBi2, which causes smaller σSH than that of alloys with smaller x. The magnetic easy axis of a 0.6 nm thick Co layer points along the film normal when x is smaller than ∼0.7. Exploiting these characteristics, we show current-induced magnetization switching in the heterostructures. The efficiency to switch a perpendicularly magnetized Co layer is the largest when x ∼ 0.5. These results demonstrate the potential of Pt1−xBix alloys for spin–orbit torque magnetization switching devices.
Femtosecond XUV–IR induced photodynamics in the methyl iodide cation
Authors: Murillo-Sánchez Marta L , Reitsma Geert , Poullain Sonia Marggi , Fernández-Milán Pedro , González-Vázquez Jesús , de Nalda Rebeca , Martín Fernando , Vrakking Marc J J , Kornilov Oleg , Bañares Luis 
Published: June 2021

Abstract
The time-resolved photodynamics of the methyl iodide cation (CH3I+) are investigated by means of femtosecond XUV–IR pump–probe spectroscopy. A time-delay-compensated XUV monochromator is employed to isolate a specific harmonic, the 9th harmonic of the fundamental 800 nm (13.95 eV, 88.89 nm), which is used as a pump pulse to prepare the cation in several electronic states. A time-delayed IR probe pulse is used to probe the dissociative dynamics on the first excited

A

̃

A

1

2

state potential energy surface. Photoelectrons and photofragment ions—

C
H

3

+

and I+—are detected by velocity map imaging. The experimental results are complemented with high level ab initio calculations for the potential energy curves of the electronic states of CH3I+ as well as with full dimension on-the-fly trajectory calculations on the first electronically excited state

A

̃

A

1

2

, considering the presence of the IR pulse. The

C
H

3

+

and I+ pump–probe transients reflect the role of the IR pulse in controlling the photodynamics of CH3I+ in the

A

̃

A

1

2

state, mainly through the coupling to the ground state

X

̃

E

3
/
2
,
1
/
2

2

and to the excited

B

̃

E

2

state manifold. Oscillatory features are observed and attributed to a vibrational wave packet prepared in the

A

̃

A

1

2

state. The IR probe pulse induces a coupling between electronic states leading to a slow depletion of

C
H

3

+

fragments after the cation is transferred to the ground

X

̃

E

3
/
2
,
1
/
2

2

states and an enhancement of I+ fragments by absorption of IR photons yielding dissociative photoionization.
Probing top-philic new physics via four-top-quark production *
Authors: Cao Qing-Hong , Fu Jun-Ning , Liu Yandong , Wang Xiao-Hu , Zhang Rui 
Published: June 2021

Abstract
We explore constraints on various new physics resonances from four top-quark production based on current experimental data. Both light and heavy resonances are studied in this work. A comparison of the full width effect and narrow width approximation is also presented.
Note on gauge invariance of second order cosmological perturbations *
Authors: Chang Zhe , Wang Sai , Zhu Qing-Hua 
Published: June 2021

Abstract
We study the gauge invariant cosmological perturbations up to the second order. We demonstrate that there are infinite families of gauge invariant variables at both the first and second orders. The conversion formulae among different families are verified to be described by a finite number of bases that are gauge invariant. For the second order cosmological perturbations induced by the first order scalar perturbations, we explicitly represent their equations of motion in terms of the gauge invariant Newtonian, synchronous and hybrid variables, respectively.