bluuebunny/crossref_metadata_2025_split huggingface dataset:
Demystifying COVID-19 lung pathology
Authors: Bhandari Sudhir , Solanki Ranjana , Jindal Arpita , Rankawat Govind , Pathak Deepali , Bagarhatta Meenu , Singh Ajeet 
Published: July 2021

Background:
Atypical presentation of coronavirus disease-19 (COVID-19) from classic acute respiratory distress syndrome needs to be extensively evaluated to understand the pathophysiology to optimize the management protocol for severely ill patients to abrogate the terminal event.

Methods:
Autopsy core needle biopsies of lungs were obtained from 12 patients who died with COVID-19. Routine histopathological examination of lung tissue along with immunohistochemical analysis of C4d complement staining was studied. Formalin-fixed paraffin-embedded biopsy material was also subjected to real-time reverse transcription-polymerase chain reaction for severe acute respiratory syndrome – coronavirus (SARS-CoV2) gene.

Results:
In the study, all the deceased patients were symptomatic with two-thirds suffering from isolated SARS-CoV2-related pneumonia while remaining one-third had secondary COVID-19 infection. Histopathological evaluation highlights diffuse alveolar damage as the predominant pattern; however, complement-mediated endothelial injury of septal microvasculature, and microthrombi was also distinctly observed with increased serum levels of D-Dimer and fibrinogen-degradation products. The patients who had extrapulmonary manifestations at the time of presentation also showed pulmonary vascular lesions on histopathologic examination. Our study confirms the presence of coagulopathy and immune-mediated microthrombi in pulmonary septal microvasculature in patients with severe disease.

Conclusion:
The results of our small series of patients highlight the possibility of immune-mediated pulmonary vascular injury and thrombosis which has the potential to evolve into large vessel thrombosis and pulmonary embolism in critically ill patients. Definitive therapeutic management protocol including thromboembolic prophylaxis and development of effective immune-modulatory target could possibly reduce mortality in severely ill patients.
Integration of E-learning into the Physiology Education of Medical Students in their Pre-clinical Curriculum
Authors: Menon Bindu , Patel Radha , Kovacs Kelly , Prevette Christopher , Chen Tian , Matus Coral D 
Published: July 2021

Purpose: In our institution, we initiated integrated learning in the format of Learning Modules (LM), interactive audio/visual modules developed by the faculty in alignment with session learning objectives, as pre-work for in-class sessions.?This pilot study examined students’ perceptions of this new learning method and effectiveness in helping them achieve content mastery.
Methods: The instructor provided the LMs in advance, allowing a self-paced introduction of critical concepts that were subsequently discussed in detail during the in-class learning (ICL) session. A cognitive diagnostic assessment was used to analyze the student's performance on the exams. This involved identifying six skills, one or more of which were marked to be necessary for answering each exam question correctly. A question-by-skill Q-matrix was constructed, followed by analysis using a Deterministic Input, Noisy "And" Gate (DINA) model.
Results: 70% of the students rated the new approach as "Excellent or Good." 63% of the students attained skills necessary to answer questions that involved integrating information gained separately from LM and ICL sessions. However, only 23% of the students achieved mastery in all the 6 skills.
Conclusion: This integrative learning system allowed for time optimization since ICL sessions could focus on more interactive aspects of the content.
Penerapan Teknik Modeling Simbolis Dalam Pengembangan Perencanaan Karier Siswa SMPN 6 Palangka Raya
Authors: Yulia Yulia , Bunu Helmuth Y , Suriatie Mimi , Lena Makda Del , Samuda Rahmaniah 
Published: July 2021

Career planning is something that concerns the future in the long term. It must be planned in advance; to plan where someone wants to go and what he wants to achieve.The purpose of this study was to determine the effectiveness of symbolic modeling techniques in the development of student career planning; to choose further studies that suit their interests and talents. The type of the research is qualitative research with observation, interview, and documentation methods. The research subjects were 5 students. This research was carried out based on the phenomenon at SMP Negeri 6 Palangka Raya, where there were students who were still confused about choosing further studies according to their interests and talents. The results showed that after being given symbolic modeling with videos, students experienced changes such as: (1) Students were able to understand their strengths and weaknesses in certain fields; (2) Students begin to be able to plan careers after graduating from school; (3) Students were able to prepare options for the next level of study. From these data the researchers concluded that symbolic modeling was effective in helping students at SMP Negeri 6 Palangka Raya in planning their careers.
Penilaian Komitmen Kerja Guru Dalam Pengembangan Total Quality Management Modern di SMPIT/SMAIT Insan Mandiri Cibubur
Authors: Arisanti Risa , Sa’diyah Maemunah 
Published: July 2021

This study aims to determine the implementation of modern integrated quality management (Total Quality Management/TQM) at SMPIT/SMAIT Insan Mandiri Cibubur, especially in the development of teacher performance evaluation assessment programs, by adding an assessment of teacher work commitment. This study uses qualitative research methods with in-depth interviews with informants. The results of the study show that SMPIT/SMAIT Insan Mandiri Cibubur has implemented a modern Total Quality Management system, with various superior customer-oriented programs. The school is trying to innovate continuously in improving the quality of education. One of the main focuses is improving the quality of teachers, as the heart of the educational process itself, which is in direct contact with students as the main external customers. Not only the teacher's competence factor, but the teacher's commitment factor, is something that needs to be considered, because it will affect the quality of teaching that will be received by students.
The teacher commitment factor is included in the evaluation criteria for teacher performance evaluation, and the results of the assessment will affect the amount of teacher performance allowances. As a result, there is a strengthening of teacher work commitment, which results in better teacher work competencies, thereby increasing the success of student achievement.
Keywords: Total Quality Manajement, Modern, Commitment, Teacher

ABSTRAK
Penelitian ini bertujuan untuk mengetahui implementasi manajemen mutu terpadu (Total Quality Management/TQM) modern di SMPIT/SMAIT Insan Mandiri Cibubur, khususnya dalam pengembangan program penilaian evaluasi kinerja guru, dengan menambahkan penilaian komitmen kerja guru. Penelitian ini menggunakan metode penelitian kualitatif dengan teknik wawancara mendalam terhadap informan. Hasil penelitian menunjukkan bahwa SMPIT/SMAIT Insan Mandiri Cibubur telah menerapkan sistem Total Quality Management secara modern, dengan memiliki berbagai program unggulan yang berorientasi pelanggan. Pihak sekolah berusaha melakukan inovasi terus-menerus dalam meningkatkan kualitas pendidikan. Salah satu fokus utama adalah peningkatan kualitas guru, sebagai jantung dari proses pendidikan itu sendiri, yang bersentuhan langsung dengan siswa sebagai pelanggan eksternal utama. Tidak hanya faktor kompetensi guru, namun faktor komitmen guru, menjadi hal yang perlu diperhatikan, karena akan mempengaruhi kualitas pengajaran yang akan diterima oleh siswa.
Faktor komitmen guru dimasukkan ke dalam kriteria penilaian evaluasi kinerja guru, dan hasil penilaian akan mempengaruhi besaran tunjangan kinerja guru. Sebagai hasilnya, terjadi penguatan komitmen kerja guru, yang menghasilkan kompetensi kerja guru yang lebih baik, sehingga meningkatkan keberhasilan prestasi belajar siswa.

Kata kunci: Manajemen Mutu Terpadu, Modern, Komitmen, Guru
Neuroprotective role of Glycyrrhiza glabra on chronic noise induced changes in Hippocampal morphology and its functions in wistar albino rats
Authors: Arjunan Archana , Sah Dhiraj Kumar , Rajan Ravindran 
Published: July 2021

Background: Noise has become inexorable stress due to the increase in urbanization, automobile usage, and lifestyle modification.Aim: The study aims to investigate the effect of chronic noise stress on hippocampal morphology and the neuroprotective effect of Glycyrrhiza glabra (GG) on stress-induced male Wistar albino rats. Methods: Adult albino rats were randomly divided into four groups. Each group contained six animals. Rats exposed to chronic noise stress (100 dB/4 h – 30Days), Noise + GG (150 mg/kg Bw/Oral), and GG alone were compared with control animal and assessed for behaviour using the hole-board test, marble burying test, the morphology of hippocampus by histology, DNA fragmentation and assessed the Phytochemical constitutes in GG. Results: The rats exposed to chronic noise stress showed significance (p<0.05) of behavioral alterations such as increased fear and anxiety, obsessive-compulsive behaviour, enlarged lateral ventricle, and reduced hippocampal volume. Conclusion: The results reported that chronic noise stress affects the neurobehavioral due to reduced hippocampal volume.
Perception and Readiness towards Indian Ayurvedic Medicine Acceptance to Combat COVID-19 Outbreak: A Multigroup Analysis in PLS Path Modelling
Authors: Baskaran Shathees , Nallaluthan Kesavan , Kunjuraman Velan 
Published: July 2021

Introduction–COVID-19 has come to us as a danger without a cure. Ayurvedic Medicine is seen to have the potential to be an alternative solution in curing COVID-19. Hence, the research aims to empirically investigate the adoption of Ayurvedic Medicine as an alternative cure for COVID-19 among the users and non-users. Methods–The research employed a quantitative research approach using a survey involving adults aged more than 18 years old. A convenient sampling method was chosen for this research. The collected data was analyzed by employing PLS-SEM and PLS-SEM MGA. Results – The results indicated that there is no significant difference between users and non-users of Ayurvedic medicine. All hypotheses formulated investigating Ayurvedic medicine beliefs, attitude, perception, and satisfaction in considering it as a Potential Alternative for COVID-19 were retained. Conclusion – This study has provided new insights in understanding the possibilities of using Ayurvedic medicine in curing COVID-19 and welcoming the medical practitioners of clinical research to identify the technical properties of Ayurvedic Medicine to be considered as an alternative for COVID-19 and many other existing and future diseases. The novelty of this study is two-fold. First, this is a pioneer study attempting to understand the public’s view in considering Ayurvedic medicine as an alternative in combating COVID-19. Second, the conceptual model presented in this study to bridge the critical knowledge gap of the Ayurvedic Medicine phenomenon is neither formulated nor tested empirically in previous studies, locally or perhaps globally, therefore stands out as an original incremental contribution in ayurvedic medicines perception.
Overuse: A concept analysis
Authors: McGough Kaitlyn 
Published: July 2021

Spending much of her career in clinical pediatrics, the author was greatly troubled regarding the amount of screen time in which the patients of her office were reportedly engaging. It is for this reason that the concept of "overuse" was chosen for analysis. The author explores multiple facets of overuse including social media in adolescence, caffeine, pumpkin spice, "pitcher's elbow", antibiotic prescription, and interpersonal kindness. The purpose of this concept analysis is to explore the many differing applications of the definition of overuse as well as to construct a practical definition for identification and response in the pediatric clinical setting.
Quality Improvement: Undergraduate contribution to identify barriers to patient discharge timeliness
Authors: Gatton Kelsey , Black Anamarie , Talari Preetham , Clancy Karen 
Published: July 2021

The undergraduate quality improvement project goal was to determine the primary barriers to timely discharges through a clinical leadership practicum experience at an advanced tertiary care teaching hospital. Delays in discharges are associated in the literature with adverse health outcomes and diminished efficiency within organizations. The authors retrieved deidentified data in real-time from the health information system and interactions with patient care staff. The study’s metrics included 1) discharge orders placed before 10 a.m, and 2) patients discharged before noon. The primary barriers found were ambulance transport delays and scheduled treatments after target discharge times. Early identification of patients planned to discharge aided in readiness and increased numbers of patients discharged before noon. The information collected by undergraduate students will help address the primary barriers and assist further quality improvement initiatives within the affinity group.
O CONCEITO DE PESSOA E A PERSPECTIVA EDUCACIONAL DE KAROL WOJTYLA
Authors: Santana Claudio Manoel Luiz de , Domingos Luiz Fábio , Garcia de Castro Carolina Pinheiro 
Published: July 2021

Considerando a pessoa humana como único ser capaz de se debruçar reflexivamente sobre a própria vida, o presente artigo procura conciliar a filosofia tradicional com alguns caminhos traçados no pensamento atual, principalmente o da vertente fenomenológica e responder ao questionamento: os constructos Wojtylianos sobre pessoa humana possui relevância capaz de ajudar a perspectiva educacional? O presente artigo buscou evidenciar os fundamentos do pensamento de Karol Wojtyla, mostrando ser possível conhecer a amplitude humana através de seus atos, possibilitando o acesso à interioridade do ser humano. Desse modo, definiu-se como objetivo correlacionar o conceito antropológico, no âmbito dos estudos da Filosofia e Antropologia, evidenciando com base nestes estudos o contributo para Educação. Trata-se de uma análise descritiva, com revisão bibliográfica, apoiada nos diversos resultados, mostrando que se faz necessário a compreenção da pessoa humana em sua integralidade para que seja preconizado um modelo atualizado, íntegro e fidedigno de quem é o homem.
PENGINJILAN TERHADAP MASYARAKAT PLURAL BERDASARKAN SURAT EFESUS
Authors: Ngala Erna , Mangantibe Veydy Yanto 
Published: July 2021

This article discusses evangelism to plural societies based on the epistle of ephesians. Evangelism is god’s program, design and work that bring for himself, people to fellowship, worship / praise and serve him in wholeness and harmony. Evangelism is established by god from eternity, because all things are designed by god from eternity in his omniscience and power in evangelism (eph. 1: 4-14). God wants his people to have fellowship with him, become his worshipers and serve him, the true god. The challenge in evangelism is that every religion is different, all religions have objects that are worshiped, therefore it will not be possible to be completely equated between one religion and another. Plural society equates christian faith with other beliefs by looking for loopholes to align christianity with other religions. The duty of the believer is to preach the gospel so that unbelievers hear and believe in the lord jesus and are saved, not compromising the gospel or juxtaposing christian faith with other beliefs. Keywords: Evangelism; Plural Society; Ephesians Letter AbstrakArtikel ini membahasa mengenai penginjilan terhadap masyarakat plural berdasarkan surat Efesus. Penginjilan merupakan program, rancangan dan karya Allah yang membawa bagi diriNya sendiri suatu umat untuk bersekutu, menyembah/memuji dan melayani Dia dalam keutuhan dan keserasian. Penginjilan ditetapkan Allah sejak kekekalan, sebab segala sesuatu dirancang Allah dari kekal dalam kemahatahuanNya dan kuasaNya didalam penginjilan (Ef. 1:4-14). Allah menghendaki agar umatNya bersekutu dengan Dia, menjadi penyembahNya dan melayani Dia, Allah yang benar. Tantangan dalam penginjilan adalah setiap agama berbeda, semua agama memiliki objek yang disembah, oleh sebab itu tidak akan mungkin dapat disamakan secara keseluruhannya antara agama satu dengan yang lain. Masyarakat plural, menyamakan iman Kristen dengan kepercayaan lain dengan mencari celah untuk dapat menjajarkan kekristenan dengan keagamaan lain. Tugas dari orang percaya ialah memberitakan Injil agar orang-orang yang belum percaya mendengar dan menjadi percaya kepada Tuhan Yesus serta diselamatkan, bukan mengkompromikan Injil atau menjajarkan iman Kristen dengan kepercayaan lain. Kata Kunci: Penginjilan; Masyarakat Plural; Surat Efesus
CRIME IMPOSSÍVEL: 17 CÓDIGO PENAL
Authors: Costa Andréia Dalla , Perlin Edson José 
Published: July 2021

O presente trabalho de conclusão de curso tem a pretensão de analisar, sob a ótica da legislação da doutrina e da jurisprudência, a figura do crime impossível, preservando a sua integridade na forma de conter o poder punitivo do estado no que se refere as condenações. Se não existisse o sistema de vigilância (eletrônica ou física) o crime estaria apto a se consumar, e o bem jurídico de fato, estaria em perigo? Analisar em que medida os aparatos de vigilância em estabelecimento comerciais neutralizam os perigos para o bem jurídico patrimônio, a ponto de evitar a consumação do crime na figura do crime impossível (art. 17 do Código Penal).
A tentativa inidônea afeta a tipicidade penal. Dessa forma ficou claro a conduta do agente quando há o dolo de praticar a conduta criminosa, mas a probabilidade de êxito está reduzida em grande significância na empreitada criminosa. A aplicação da tentativa inidônea depende do dolo do agente, após o início dos atos executórios, não ocorre a consumação do crime, por circunstâncias alheias à sua vontade. A investigação do grau de segurança com que se pode esperar a realização de um evento, determinado pela frequência de tentativas de consumação do delito, dando ênfase a conduta do agente, baseado em conhecimento.
The Importance of Parental Assistance in Supervising the Use of Technology for Children During the Home Learning Program
Authors: Riyan Rizaldi Dedi , Nurhayati Eris , Fatimah Ziadatul , Amni Zakiya 
Published: July 2021

Writing this article aims to provide an overview of the role of parents when assisting children in using various technologies during the learning process from home. This is because without any limitations in technology it can have a good or bad impact on children if it is not used according to the required context. Therefore, the subject of the study to be discussed is more focused on the learning of children aged 7-15 years, who in the learning process still really need assistance from their parents. Writing this article is done through a process of literature review of various literature starting from the process of determining the topic of the problem, determining the type of data collection method, collecting various data that support the topic, conducting the data analysis process, and drawing conclusions based on the data that has been obtained. Based on the data that has been obtained, the role of parents in assisting children to use technology while learning from home is very important, especially in maintaining and increasing children's motivation to continue learning.
Kepemimpinan Tuhan Yesus di Masa Krisis Sebagai Model Kepemimpinan Kristen Saat Ini
Authors: Tarigan Sayang , Hermanto Yanto Paulus , P Nira Olivia 
Published: July 2021

Abstract: Secular leadership is not the same as leadership inherited from the Lord Jesus. The leadership of Jesus is a historical and inspiring leadership model for every Christian leader from time to time. The superiority of Jesus' leadership model stems from the communication of the Father's vision to his followers with a touch of compassion which is the basis of His leadership.In this study the authors used qualitative methods. While the data collection process, the method approach used is literature study. Through a series of research conducted, there are various leadership models that are found, but the Christ leadership model provides superior characteristics and models, especially in times of crisis like today.Keywords: Leadership, Jesus, Christian.Abstrak: Kepemimpinan sekuler tidak sama dengan kepemimpinan yang diwariskan oleh Tuhan Yesus. Kepemimpinan Yesus di dunia merupakan model kepemimpinan yang bersejarah dan menginspirasi bagi setiap pemimpin Kristen dari zaman ke zaman. Keunggulan model kepemimpinan Yesus bertolak dari komunikasi visi Bapa kepada para pengikut dengan sentuhan belaskasihan yang menjadi dasar kepemimpinan-Nya. Dalam penelitian ini penulis menggunakan metode kualitatif. Sementara proses pengumpulan data, pendekatan metode yang digunakan adalah studi literatur. Melalui serangkaian penelitan yang dilakukan, terdapat beragam model kepemimpinan yang dijumpai, namun model kepemimpinan Kristus memberikan ciri dan model yang unggul, terutama dalam masa-masa krisis seperti saat ini.Kata kunci: Kepemimpinan, Yesus, Kristen.
MULTIGRAVIDA DENGAN MAKROSOMIA DAN INTRA UTERINE FETAL DEATH: SUATU STUDI KASUS DI RS ABDUL MOELOEK BANDAR LAMPUNG
Authors: Lubis Fauziah 
Published: July 2021

Latar belakang: Makrosomia adalah istilah untuk neonatus yang lahir dengan berat lebih dari 4000 gram atau berada dalam persentil 90 terhadap usia kehamilan. Makrosomia meningkatkan kejadian risiko cedera bagi ibu maupun janin selama proses persalinan. Makrosomia dapat dicegah atau dideteksi lebih awal dengan mengendalikan faktor risiko.
Ilustrasi kasus: Pada kasus, makrosomia telah menimbulkan komplikasi berupa intra uterine fetal death. Pasien didiagnosis dengan G3P1A1 hamil 37 minggu inpartu kala I fase aktif dengan ketuban pecah dini 3 jam (di luar), janin tunggal mati, presentasi kepala dan suspek makrosomia.
Penatalaksanaan: Pada pasien dilakukan penatalaksanaan berupa partus percobaan. Partus percobaan gagal dan diagnosis disproporsi kepala panggul ditegakkan, maka pada pasien dilakukan sectio caesarea.
Pemeriksaan fisik: Dilahirkan bayi laki-laki dengan berat 5400 gram, panjang 62 cm dengan maserasi grade I. Selama operasi, didapatkan warna ketuban hijau kecoklatan dan kental yang menandakan adanya proses hipoksia kronis pada janin yang menyebabkan kematian janin pada kasus ini. Pada pasien ditemukan faktor risiko berupa adanya riwayat melahirkan bayi besar sebelumnya (4100 gram). Kunjungan antenatal jarang dilakukan sehingga berat badan selama hamil tidak termonitor.
Diskusi: Laporan kasus ini menunjukkan bahwa makrosomia dapat meningkatkan risiko terjadinya komplikasi bagi ibu dan bayi terutama saat persalinan. Komplikasi dapat dihindari dengan mencegah dan mendiagnosis lebih awal adanya makrosomia dengan mengendalikan faktor risiko. Pengendalian faktor risiko dapat dilakukan dengan kunjungan antenatal yang rutin