bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Utility of aVR Lead T-Wave in Electrocardiogram of Patients With ST-Elevation Myocardial Infarction
Authors: Kazemi-Arbat Babak , Sadat-Ebrahimi Seyyed-Reza , Ranjbar Abdolmohammad , Akbarzadeh Fariborz , Sadaie Mohammad Reza , Safaei Naser , Zadeh-Saboor Mehdi Esmaeil , Sohrabi Bahram , Ghaffari Samad 
Published: July 2021

Abstract
Background

aVR lead is often neglected in routine clinical practice largely because of its undefined clinical utility specifications. Nevertheless, positive T-wave in aVR lead has been reported to be associated with poor clinical outcomes in some cardiovascular diseases. This study aimed to prospectively investigate the prognostic value and clinical utility of T-wave amplitude in aVR lead in patients with acute ST-elevation myocardial infarction (STEMI).
Methods

A total of 340 STEMI patients admitted to a tertiary heart center were consecutively included. Patients were categorized into four strata, based on T wave amplitude in aVR lead in their admission ECG (i.e. < -2, -1 to -2, -1 to 0, and ≥ 0 mV). Patients’ clinical outcomes were also recorded and statistically analyzed.
Results

In-hospital mortality, re-hospitalization, and six-month-mortality significantly varied among four T wave strata and were higher in patients with a T wave amplitude of ≥ 0 mV (p-values, 0.001 to 0.002). As the T wave amplitude in aVR increased, there was a progressive increase in relative risk (RR) of in-hospital mortality (RRs = < 0.01, 0.07, 1.00, 2.30 in four T wave strata, respectively). T wave amplitude in the cutoff point of -1 mV exhibited a sensitivity and specificity of 95.83 (95% CI, 78.88–99.89) and 49.68 (95% CI, 44.04–55.33).
Conclusion

Our study demonstrated a significant association of positive T wave in aVR lead and adverse clinical outcomes in STEMI patients. Nevertheless, the clinical utility of T-wave amplitude at aVR lead is limited by its low discriminative potential toward prognosis of STEMI.
Study on a New Process and its Kinetics of Iron Recovery and Glass-ceramics Preparation from Desulfurization Slag
Authors: Tong Zhibo , sun jingting , Liu ShiChang , Zhang Wei , Kuang MeiLing 
Published: July 2021

Abstract
The melting point and phase of slag was calculated with Factsage thermodynamics software, and base on this, taking desulfurization slag as the main raw material, which is leached by ammonium chloride as pretreatment. The composition of target slag system was adjusted with high aluminum powder coal ash and glass cullet, and then the reducing slag and metallic iron were separated by high temperature carbon thermal reaction. The prepared glass-ceramics with main crystal phases of diopside and nepheline were obtained by heat treatment, which shows that the new process is feasible. The crystallization activation energy was calculated by using Kissinger, Ozawa and Augis-Bennett method base on the differential heat curve. The results show that the crystallization activation energy is relatively high, and the crystal growth index n are all less than 3, which means that the crystallization capacity of the glass-ceramics is low. At the heating rate of 5 K/min, the n value of sample No. 3 is the largest, which is 2.7, and the mode of volumetric crystallization changes from two-dimensional to one-dimensional with the increase of heating rate, therefore, nucleating agent is needed in the preparation of glass-ceramics.
Effects of Land Use/Cover Change On Atmospheric Humidity in Three Urban Agglomerations in The Yangtze River Economic
Authors: Li Baoni , Xiong Lihua , Zhang Quan , Chen Shilei , Yang Han , Guo Shuhui 
Published: July 2021

Abstract
Land use/cover change (LUCC) affects regional climate not only through its direct changes of land surface properties, but also through its further modifications of land-atmosphere interactions. Urban land expansion is a typical case of LUCC in highly populated areas, and has been widely discussed about its impacts on regional air temperature, notably known as urban heat island (UHI) effects. Besides air temperature, atmospheric humidity, as another key variable in hydrometeorology and climate, would be inevitably affected by LUCC as well. However, the impacts of LUCC on atmospheric humidity seem to have not been investigated as much as on temperature. We examined atmospheric humidity changes by trend analyses of humidity indicators in three representative urban agglomerations in the Yangtze River Economic Belt (YREB), China during 1965-2017, and found the evident urban dry island (UDI) effects which are characterized by significant humidity decrease and vapor pressure deficit increase. In different urban cores, the severity levels of UDI are different. Furthermore, strong positive correlations between humidity and evapotranspiration, and between evapotranspiration and leaf area were detected during 2001-2017 when cities entered the accelerated stage of land expansion, indicating that LUCC affects regional climate through an ecohydrological way. We speculated that the UDI effect will not appear until urban land expands to a certain scale. Besides, the UHI effect emerged in the early stage of urban expansion, about 5 years earlier than the UDI effect, and has not performed prominently in recent years. This implies that urbanization-induced LUCC may exert a larger influence on UDI than on UHI in the current later period of urban expansion.
Mobile Health Applications Interventions For Prediabetic State: Protocol of Systematic Review
Authors: Jeem Yaltafit Abror , Nabila Refa , Emelia Dwi Ditha , Lazuardi Lutfan , Josef Hari Kusnanto 
Published: July 2021

Abstract
Background: Individuals with prediabetic state are much more likely to develop Type-2 Diabetes Mellitus (TD2M) 4 times greater than those with normal glucose tolerance. Lifestyle changes such as daily physical activity and healthy diets can decrease the risk of prediabetic state . Mobile applications intervention could be one of the solutions to improve self-management awareness and compliance of prediabetic state intervention. There are no studies in systematic reviews of mobile phone applications intervention to prevent prediabetic state yet. Therefore, the objective of this study was to collect and summarize the evidence from randomized controlled trials (RCTs) exploring the effectiveness of mobile phone applications for intervention in prediabetic state patients.Methods: This protocol was prepared in accordance with the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) statement. The database that will be used includes PubMed, ProQuest and EBSCO with date restriction between January 2007 and July 2019 in English language only. Identification of articles will be done independently by three reviewers through the title of the articles, reviewing the abstract, and then the full-text-article. Any disagreement will be resolved by consensus. The quality assessment and possible risk of bias will be evaluated using forms adapted from the Jadad score. Extraction and content analysis will be performed systematically. Quantitative data will be presented graphically via forest plot with 95% confidence intervals. Where possible we will explore the heterogeneity and continue to conduct meta-analysis using RevMan software package. Discussion: Changes in lifestyle, such as daily physical activity and a nutritious diet, can help to reduce the risk of prediabetes. Mobile phone applications, including health-related applications, is demonstrated to have a lot of promise in terms of providing tailored medical recommendations. Conclusion: The proposed systematic review and meta-analyses will allow us to obtain the evidence exploring the effectiveness of mobile phone applications for intervention in prediabetic state patients.Systematic review registration: This protocol has been registered in the Prospective Registry of Systematic Review (PROSPERO) database (CRD42021243813).
A Stochastic SIS Epidemic Model with Ornstein-Uhlenbeck Process and Brown Motion
Authors: Chen Xingzhi , Tian Baodan , Xu Xin , Yang Ruoxi , Zhong Shouming 
Published: July 2021

Abstract
This paper studies a stochastic differential equation SIS epidemic model, disturbed randomly by the mean-reverting Ornstein-Uhlenbeck process and Brownian motion. We prove the existence and uniqueness of the positive global solutions of the model and obtain the controlling conditions for the extinction and persistence of the disease. The results show that when the basic reproduction number Rs0 < 1, the disease will extinct, on the contrary, when the basic reproduction number Rs0 > 1, the disease will persist. Furthermore, we can inhibit the outbreak of the disease by increasing the intensity of volatility or decreasing the speed of reversion ϑ, respectively. Finally, we give some numerical examples to verify these results.
A Categorial Equivalence for Semi-Nelson Algebras
Authors: Cornejo Juan Manuel , Gallardo Andrés , Viglizzo Ignacio Darío 
Published: July 2021

Abstract
We present a category equivalent to that of semi-Nelson algebras. The objects in this category are pairs consisting of a semi-Heyting algebra and one of its filters. The filters must contain all the dense elements of the semi-Heyting algebra and satisfy an additional technical condition. We also show that the category of dually hemimorphic semi-Nelson algebras is equivalent to that of dually hemimorphic semi-Heyting algebras.
The Effect of Thyroid Hormone Withdrawal, Performed to Evaluate the Success of I-131 Ablation, On Quality of Life in Female Patients With Low-Risk Differentiated Thyroid Cancer
Authors: Kupik Osman , Şen Bayram , Arpa Medeni , Akça Levent , Avcı Uğur , Eren Gülnihan , Gündoğdu Hasan , Kalcan Süleyman , Güçer Hasan , Akın Şafak , Tuncel Murat 
Published: July 2021

Abstract
Objective: There is a need to evaluate the treatment response in patients who have undergone radioiodine treatment (RIT) for differentiated thyroid cancerDiagnostic tests that are used for this purpose include radioiodine whole body scan (sWBS) and serum thyroglobulin (Tg) measurement which are most accurate during thyroid-stimulating hormone (TSH) stimulation. However temporary discontinuation of thyroid hormone therapy to increase TSH (withdrawal) may be associated with the morbidity of hypothyroidism The aim of our study was to show the effects of thyroid hormone withdrawal (THW), on quality of life and psychological symptoms in female patients with low-risk, well-differentiated papillary thyroid cancer. Methods: We applied the short form-36 (SF-36) and Symptom Checklist-90-R (SCL-90-R) questionnaires to the patients in the euthyroid state who were referred a median of 9 months (6-13 months) after RIT, to perform a dWBS and to evaluate stimulated Tg. We applied the same questionnaire again when thyroid-stimulating hormone (TSH) was > 30 μIU/mL 4 weeks after THW (hypothyroid state). We evaluated the changes in questionnaire scores using the paired-samples t test or the Wilcoxon signed rank test. Results: Our study included 52 patients (median age 48 years, range 23-65 years) with differentiated cancer. Forthy –two (%) of these patients received 3700 MBq I-131 wheras 7 (%) patients received 1850 MBq. . Ablation success based on the dWBS only was 96.2%, based on Tg only was 98% and based on thyroglobulin antibodies (TgAb) only was 88.5%. There was statistically significant worsening in anxiety, psychosis, additional items and general symptom index symptoms with the SCL-90-R questionnaire, and physical functioning, role limitation due to physical health, energy/fatigue, emotional well-being, social function, general health and health change with the SF-36 questionnaire. Conclusions: THW worsened the patients’ psychological symptoms and quality of life. Our findings show that stimulated Tg and the dWBS may have side effects that outweigh benefits in patients with low-risk differentiated thyroid cancer without TgAb interference and access to ultrasonography.
S = ½ Heterospin Frustration in a Metal‒Fullerene-Bonded Semiconductive Antiferromagnet
Authors: Shen Yongbing , Cui Mengxing , Takaishi Shinya , Tsumuraya Takao , Otsuka Akihiro , Kwon Eunsang , Yoshida Takefumi , Hoshino Norihisa , Kawachi Kazuhiko , Kasama Yasuhiko , Akutagawa Tomoyuki , Yamashita Masahiro 
Published: July 2021

Abstract
Lithium-ion-encapsulated fullerenes (Li+@C60) are 3D superatoms with rich oxidative states. However, no current studies have reported Li+@C60 as ligands. Here, we report a conductive and magnetically frustrated metal–fullerene-bonded framework {[Cu4(Li+@C60)(L)(py)4](NTf2)(hexane)n (1) prepared from redox-active dinuclear metal complex Cu2(L)(py)4 and lithium-ion-encapsulated fullerene salt (Li+@C60)(NTf2−), where ligand L denotes 1,2,4,5-tetrakis(methanesulfonamido)benzene, py pyridine, and NTf2− the bis(trifluoromethane)sulfonamide anion. Electron donor Cu2(L)(py)2 bonds to acceptor Li+@C60 via eight Cu‒C bonds. Cu–C bond formation stems from spontaneous charge transfer (CT) between Cu2(L)(py)4 and (Li+@C60)(NTf2−) by removing the two-terminal py molecules, yielding triplet ground state [Cu2(L)(py)2]+(Li+@C•‒ 60), evidenced by absorption and electron paramagnetic resonance (EPR) spectra, magnetic properties, and quantum chemical calculations. Moreover, Li+@C•‒ 60 radicals (S = ½) and Cu2+ ions (S = ½) interact antiferromagnetically in triangular spin lattices in the absence of long-range magnetic ordering up to 1.8 K; thus, compound 1 is a potential candidate for an S = ½ quantum spin liquid.
Priority micronutrient density in foods
Authors: Beal Ty , Ortenzi Flaminia 
Published: July 2021

Abstract
Background: Despite concerted efforts to improve diet quality and reduce malnutrition, micronutrient deficiencies remain widespread globally, especially in low- and middle-income countries and among population groups with increased needs, where diets are often inadequate in iron, zinc, folate, vitamin A, calcium, and vitamin B12. There is a need to understand the density of these micronutrients and their bioavailability across diverse foods and the suitability of these foods to help meet requirements for populations with high burdens of micronutrient malnutrition.Objective: We aimed to identify the top food sources of these commonly lacking micronutrients, which are essential for optimal health, to support efforts to reduce micronutrient malnutrition among various populations globally.Methods: We built an aggregated global food composition database and calculated recommended nutrient intakes for five population groups with varying requirements. An approach was developed to rate foods according to their density in each and all priority micronutrients for various population groups with different nutrient requirements.Results: We find that the top sources of priority micronutrients are organs, small fish, dark green leafy vegetables, bivalves, crustaceans, beef, goat, eggs, milk, cheese, and canned fish with bones. Lamb, mutton, goat milk, and pork are also good sources, and to a lesser extent, yogurt, fresh fish, pulses, and teff.Conclusions: The results provide insight into which foods to prioritize to fill common micronutrient gaps and reduce undernutrition.
Ramet specialization allows similar performance of the invasive macrophyte Hedychium coronarium under different light and intraspecific competition levels
Authors: Costa Rosane Oliveira , Batisteli Augusto Florisvaldo , Almeida Renata Vilar , de Castro Wagner Antônio Chiba , Espindola Evaldo Luiz Gaeta , Matos Dalva Maria da Silva 
Published: July 2021

Abstract
Invasive species can affect ecosystems functioning by forming dense monospecific stands and outcompeting native plants. However, the performance of the invader depends on its plastic responses to abiotic attributes of invaded communities. Understanding the interplay between intraspecific competition and environmental conditions is important to elucidate the domain and aggressive potential of invasive species. Here, we assessed the performance of the invasive Hedychium coronarium in two levels of intraspecific competition created through rhizome density under full light and partial shade. We tested the influence of light, density and their interaction on ramet length and number of ramets during the first three months after planting (phase 1) and after 22 months (phase 2), and on rhizome dry weight and the ramet/rhizome biomass ratio in phase 2. In both phases, ramets were longer under shade and the number of ramets was higher under low rhizome density indicating lower intraspecific competition. In phase 2, there was a negative effect of rhizome density on ramet length, but it was restricted to shade, probably due to the aggravation of competition for light. Rhizome dry weight was greater under shade conditions and it was not affected by rhizome density, and ramet/rhizome ratio did not differ between treatments. Our results supported a large phenotypic plasticity of H. coronarium ramets, which allowed similar performances despite variations in environmental conditions and population densities. We suggest that this mechanism of energy allocation enhances the success of this invasive plant in varied habitats, such as open and closed, forested sites.
Menstrual Hygiene Practice among Adolescent Girls in Ethiopia: a systematic review and meta-analysis
Authors: Sahiledengle Biniyam , Atlaw Daniel , Kumie Abera , Tekalegn Yohannes , Woldeyohannes Demelash , Agho Kingsley Emwinyore 
Published: July 2021

Abstract
Background: Adolescent girls face several challenges relating to menstruation and its proper management. Lack of adequate sanitary products, inadequate water supply, and privacy for changing sanitary pads continue to leave adolescent girls with limited options for safe and proper menstrual hygiene in many low-income settings, including Ethiopia. These situations are also compounded by societal myths, stigmas surrounding menstruation, and discriminatory social norms. This systematic review and meta-analysis aimed to estimate the pooled proportion of safe menstrual hygiene management among adolescent girls in Ethiopia using the available studies. Methods: We searched PubMed, Google Scholar, African Journal Online (AJOL), Hinari, Science Direct, ProQuest, Direct of Open Access Journals, POPLINE, and Cochrane Library database inception to May 31, 2021. Studies reporting the proportion of menstrual hygiene management among adolescent girls in Ethiopia were considered. The Cochrane Q test statistics and I2 tests were used to assess the heterogeneity of the included studies. Since the included studies revealed considerable heterogeneity, a random effect meta-analysis model was used to estimate the pooled proportion of safe MHM. Results: Of 1,045 identified articles, 22 studies were eligible for analysis (n=12,330 participants). The overall pooled proportion (PP) of safe MHM in Ethiopia was 52.69% (95%CI: 44.16, 61.22). The use of commercial menstrual absorbents was common 64.63% (95%CI: 55.32, 73.93, I2 99.2%) followed by homemade cloth 53.03% (95%CI: 22.29,83.77, I2 99.2%). Disposal of absorbent material into the latrine was the most common practice in Ethiopia 62.18% (95%CI:52.87,71.49, I298.7%). One in four girls reported missing one or more school days during menstruation (PP: 32.03%, 95%CI: 22.65%, 41.40%, I2 98.2%). Conclusion: This study revealed that only half of the adolescent girls in Ethiopia had safe MHM practices. To ensure that girls in Ethiopia can manage menstruation hygienically and with dignity, strong gender-specific water, sanitation, and hygiene (WASH) facilities along with strong awareness creation activities at every level are needed.
Gut Dysbiosis and Hemodynamic Changes as Links of the Pathogenesis of Complications of Cirrhosis
Authors: Maslennikov Roman , Ivashkin Vladimir , Efremova Irina , Poluektova Elena , Shirokova Elena , Ivashkin Konstantin , Kudryavtseva Anna , Krasnov George Biology V.A.Engelgardt 
Published: July 2021

Abstract
Background. Hemodynamic changes (hyperdynamic circulation) and gut dysbiosis are observed in cirrhosis. It was suggested that gut dysbiosis contributes to the development of hyperdynamic circulation, which aggravates the course of cirrhosis. The aim is to test this hypothesis.Methods. The cross-sectional observational study included 47 patients with cirrhosis. Stool microbiome was assessed using 16S rRNA gene sequencing. Echocardiography with a simultaneous assessment of blood pressure and heart rate was performed. Hemodynamic parameters were calculated. Results. Hyperdynamic circulation was found in 34% of patients. Patients with hyperdynamic circulation had higher incidences of clinically significant ascites (p=0.018), overt hepatic encephalopathy (p=0.042), hypoalbuminemia (p=0.011), hypoprothrombinemia (p=0.019), systemic inflammation (p=0.002), and severe hyperbilirubinemia (p=0.042) than patients without hyperdynamic circulation. The abundance of Proteobacteria (p=0.012), Enterobacteriaceae (p=0.008), Bacilli (p=0.027), Streptococcaceae (p=0.044), Lactobacillaceae (p=0.034), Enterococcaceae (p=0.046), and Fusobacteria (p=0.026) increased and the abundance of Bacteroidetes (p=0.049) and Erysipelotrichia (p=0.029) decreased in the gut microbiome of patients with hyperdynamic circulation compared to patients without hyperdynamic circulation. The systemic vascular resistance value negatively correlated with the abundance of Proteobacteria (r=-0.423; p=0.003), Enterobacteriaceae (r=-0.417; p=0.004), and Fusobacteria (r=-0.401; p=0.005). Heart rate was negatively correlated with the abundance of Bacteroidetes (r=-0.453; p=0.001). The cardiac output value was positively correlated with the abundance of Proteobacteria (r=0.402; p=0.003), Enterobacteriaceae (r=0.424; p=0.003), Fusobacteria (r=0.281; p=0.049), and Bacilli (r=0.314; p=0.031), and negatively correlated with the abundance of Bacteroidetes (r=-0.313; p=0.032) and Erysipelotrichia (r=-0.329; p=0.024). Conclusion. Gut dysbiosis is associated with hyperdynamic circulation, which is associated with a number of complications of cirrhosis.
Improved Neural Network Adaptive Control for Compound Helicopter with Uncertain Cross-Coupling in Multimodal Maneuver
Authors: Zheng Fengying , Xiong Bowei , Zhang Jingyang , Zhen Ziyang , Wang Feng 
Published: July 2021

Abstract
The main goal of this study was to create a robust control system that could guide or replace the pilots in tracking of commanded velocity and attitude in multimodal maneuver, while complex dynamics and uncertain aerodynamic cross-coupling among control surfaces of compound helicopter are considered. To this end, a Pi-Sigma neural network (PSNN) adaptive controller is proposed based upon the certainty-equivalence (CE) principle, where a novel Lyapunov-based weight self-tuning algorithm augmented with e-modification is designed to realize efficient uncertainty approximation and guarantee robustness of convergence process. Compared with traditional neural networks in control field, stronger generalization ability of PSNN must be balanced against weaker stability, which leads to inevitable parameters perturbation. Therefore, an incremental nonlinear dynamic inversion (INDI) framework is established to decouple original overactuated system and reject parameters perturbation in PSNN. Meanwhile, by incorporating Lagrang- multiplier method into allocation, an original incremental allocation method is designed to get globally ideal control input according to time-varying working capability of each surface. In terms of Lyapunov theorem, it is demonstrated that the closed-loop augmented system driven by the proposed control scheme is semi-global uniformly ultimately bounded (SGUUB). Finally, the simulation result validates the effectiveness of proposed control scheme.