bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN PENGETAHUAN DENGAN SIKAP TERHADAP ABORSI KRIMINALIS PADA REMAJA PUTRI DI SMA TAMAN MULIA TAHUN 2017
Authors: Elise Putri Alexander, 
Published: August 2021

HUBUNGAN PENGETAHUAN DENGAN SIKAP TERHADAP ABORSI KRIMINALIS PADA REMAJA PUTRI DI SMA TAMAN MULIA TAHUN 2017Alexander1, Elise Putri2Akademi Kebidanan Panca Bhakti PontianakEmail korespondensi: akbidpbpontianak@gmail.comAbstrak
Aborsi kriminalis adalah aborsi yang terjadi akibat tindakan yang tidak legal atau tidak berdasarkan indikasi medis. Angka kejadian aborsi di Indonesia di perkirakan mencapai 2,3 juta pertahun, sekitar 750.000 dilakukan oleh remaja. Hasil studi pendahuluan di SMA Taman Mulia adalah terdapat 4 siswi yang dikeluarkan dari sekolah karena hamil diluar nikah dan hasil wawancara dari 8 responden bahwa sebagian besar yang mengetahui tentang aborsi kriminalis yaitu 3 (37,5%). Penelitian ini bertujuan untuk mengetahui Hubungan Pengetahuan Dengan Sikap Terhadap Aborsi Kriminalis Pada Remaja Putri Tentang Aborsi Kriminalis Di SMA Taman Mulia Tahun 2017. Penelitian ini menggunakan desain penelitian analitik korelasi dengan pendekatan cross sectional. Populasi sebanyak 79 siswi dan jumlah sampel 44 siswi dengan teknik sampling aksidental. Instrument penelitian ini menggunakan kuesioner. Hasil penelitian pengetahuan remaja putri tentang aborsi kriminalis yaitu sebagian besar berpengetahuan cukup yaitu 29 (65,90%), sebagian kecil berpengetahuan baik yaitu 13 (29,54%), sedangkan berpengetahuan kurang yaitu 2 (4,54%) dan sikap remaja putri sebagian besar bersikap tidak mendukung yaitu 28 (63,63%) dan sebagian kecil bersikap mendukung 16 (36,36%). Dari uji statistik X2 hitung = 0,072 < X2 tabel 5,991 dan hasil dari p value 0,891 > 0,05, maka Ha ditolak dan Ho diterima. Pengetahuan remaja putri tentang aborsi kriminalis yaitu sebagian besar berpengetahuan cukup yaitu 29 (65,90%), dan bersikap tidak mendukung yaitu 28 (63,63%) serta hasil uji statistik X2 hitung = 0,072 < X2 tabel 5,991 dan hasil dari p value 0,891 > 0,05 dengan demikian dapat disimpulkan bahwa tidak ada hubungan pengetahuan dengan sikap terhadap aborsi kriminalis pada remaja putri di SMA Taman Mulia Tahun 2017. Oleh karena itu disarankan untuk meningkatkan pengetahuan siswi dengan memberikan banyak informasi mengenai aborsi kriminalis, serta bekerja sama dengan puskesmas atau institusi kesehatan untuk pemberian materi tentang aborsi kriminalis kemudian untuk membentuk program genre (PIK-KRR).Kata Kunci: Pengetahuan, Sikap, Aborsi Kriminalis
HUBUNGAN ANTARA PENGETAHUAN IBU NIFAS DENGAN SIKAP DALAM MELAKUKAN PERAWATAN PAYUDARA DI RUMAH SAKIT KARTIKA HUSADA KABUPATEN KUBU RAYA TAHUN 2017
Authors: Melyani Yuliana, 
Published: August 2021

HUBUNGAN ANTARA PENGETAHUAN IBU NIFAS DENGAN SIKAP DALAM MELAKUKAN PERAWATAN PAYUDARA DI RUMAH SAKIT KARTIKA HUSADA KABUPATEN KUBU RAYA TAHUN 2017Yuliana1, Melyani2Akademi Kebidanan Panca Bhakti PontianakEmail korespondensi: akbidpbpontianak@gmail.comAbstrak
Perawatan Payudara merupakan suatu tindakan merawat payudara yang dilaksanakan baik oleh pasien maupun dibantu orang lain yang dilaksanakan mulai dari hari pertama atau kedua setelah melahirkan. Payudara bengkak biasanya terjadi pada hari-hari pertama kelahiran bayi, data yang didapatkan dari Rumah Sakit Kartika Husada pada bulan Januari hingga Maret 2017 terdapat lima kali kejadian payudara bengkak. Tujuan penelitian ini adalah untuk mengetahui hubungan antara pengetahuan ibu nifas dengan sikap dalam melakukan perawatan payudara di Rumah Sakit Kartika Husada Tahun 2017. Penelitian ini menggunakan metode analitik korelasi dengan pendekatan cross sectional, teknik pengumpulan data menggunakan kuisioner dengan jumlah sampel pada bulan April sebanyak 40 responden yaitu ibu nifas yang mendapat pelayanan di Rumah Sakit Kartika Husada. Analisis data menggunakan analisis univariat untuk menguji pengetahuan dan sikap responden dan analisis bivariat untuk mengetahui hubungan antara variabel. Hasil penelitian univariat dengan distribusi frekuensi menunjukkan bahwa sebagian responden (52,5%) berpengetahuan kurang, kategori sikap menunjukkan bahwa sebagian responden (52,5%) memiliki sikap tidak mendukung. Hasil analisis bivariat dengan distribusi Chi-Square diperoleh nilai 0,01 (p-value < 0,05). Hasil analisis bivariat menunjukkan bahwa sangat sedikit dari responden (19%) yaitu 4 orang berpengetahuan kurang dengan sikap mendukung. Kesimpulan penelitian ini yaitu ada hubungan antara pengetahuan ibu nifas dengan sikap dalam melakukan perawatan payudara di Rumah Sakit Kartika Husada tahun 2017. Saran kepada petugas kesehatan untuk melakukan penyuluhan tentang perawatan payudara dengan cara membagikan brosur, leaflet atau menempelkan gambar tentang perawatan payudara.Kata Kunci: Pengetahuan, Sikap, Perawatan Payudara, Ibu Nifas
IN THE INSIDE-OUT WORLD: MADNESS AS A THEME AND PLOT
Authors: Vasylenko Vadym 
Published: August 2021

The paper focuses on the madness as a theme and plot in Ukrainian literature of the 1st half of the 20th century. The researcher analyzes ideological and aesthetic tendencies associated with the understanding of the madness phenomenon, clarifies its functional features, symbolic and ideological significance, and emphasizes the connection between the psychological atmosphere of the totalitarian reality and literary interpretations of madness. The analysis involves works of different genres, styles, and dates of writing in which the theme of madness acquires ideologically engaged and symbolically significant content.
In “Sanatorium Zone” by M. Khvylovyi the madness phenomenon is associated with the problems of split personality and suicide. It may be explained in a modernist context, as a reflection of the internally conflicting nature of a man, incapable of changing the existing world or getting adjusted to it.
In the tragicomedy “People’s Malakhiy”, M. Kulish introduced the idea of madness into the complex sociopolitical context of the soviet reality which he revealed in various forms (from mythological to social-political) using satirical and grotesque images, philosophical generalization, etc.
An episode of madness in the novel “The Garden of Gethsemane” by I. Bahrianyi emphasizes the anomality of the soviet world which is symbolized by the punishment cell and characterized as a “conveyor belt for dismantling human souls”.
The story of the romantic poet Hӧlderlin in the novel by V. Domontovych is socially and politically conditioned. It reveals the state of a man and the world in a difficult transitional era. In “The Enameled Bowl”, Domontovych elaborates the theme of illness through the idea of the lack of consistency between the internal and external and understands it as an artistic convention that marks the absurdity of the world.
T. Osmachka in his prose was especially focused on the theme of madness. He was interested in mental disorders both as a form of the character’s self-awareness and as a clinical story. The mythological and ideological image of a mentally ill man, reflecting a creative person subjected to repression and persecution, is a symbol of his own biography.
In general, the changes in the interpretation of mental disorders are associated with the renewal of the modernist poetics and caused by the writers’ attempts to clarify the connection between the external and internal.
Faktor Risiko Terjadinya Forward Head Posture
Authors: Pangestu R Gusti Haryo Budi , Nugraha Made Hendra Satria , Saraswati Putu Ayu Sita 
Published: August 2021

Forward head posture adalah salah satu kelainan postur dimana kepala mengarah ke depan pada bidang sagital menjauhi dari garis vertikal bahu, ini dapat ditandai dengan tidak segarisnya kepala dengan bahu. Forward head posture sangat memengaruhi kehidupan manusia dimana dalam jangka panjang dapat menyebabkan nyeri leher kronis, gangguan ketegangan otot dan berpengaruh juga pada keseimbangan. Oleh karena itu identifikasi lebih lanjut terkait faktor dari forward head posture diperlukan untuk mengurangi angka kejadian di masyarakat. Tujuan penelitian ini adalah untuk mengetahui faktor risiko dari terjadinya forward head posture. Metode penelitian yang digunakan adalah literature review dengan menggunakan data dari jurnal-jurnal ilmiah yang didapat dari berbagai database jurnal ilmiah yang ada di internet. Jurnal ilmiah yang ditinjau adalah jurnal yang membahas topik tentang forward head posture, seperti definisi, faktor-faktor risiko dan prevalensi pada populasi. Berdasarkan hasil telaah jurnal didapatkan hasil bahwa forward head posture dapat terjadi apabila seseorang melakukan pekerjaan dengan postur atau sikap yang salah yaitu menekuk leher dan mencondongkan leher ke depan saat bekerja dan berulang kali dalam jangka waktu yang lama, dengan rerata durasi pekerjaan lebih dari 1 – 2,8 jam per hari. Jenis pekerjaan yang banyak menimbulkan forward head posture adalah penggunaan gawai, bekerja di depan komputer, membawa tas yang berat, dan pengoperasian mesin jahit.
Effect of Anticoagulant Administration on the Mortality of Hospitalized Patients With COVID-19: An Updated Systematic Review and Meta-Analysis
Authors: Jiang Luojia , Li Yupei , Du Heyue , Qin Zheng , Su Baihai 
Published: August 2021

Background: Anticoagulation is generally used in hospitalized patients with coronavirus disease 2019 (COVID-19) as thromboprophylaxis. However, results from different studies comparing the effect of anticoagulation on the mortality of COVID-19 patients with non-anticoagulation are inconclusive.Methods: Our systematic review included observational trials if they studied anticoagulant therapy in hospitalized patients with COVID-19 for mortality or bleeding events. Dichotomous variables from individual studies were pooled by risk ratio (RR) and their 95% confidence interval (95% CI) using the random-effects model. Grading of Recommendations Assessment, Development and Evaluation was used to assess the quality of evidence.Results: A total of 11 observational studies enrolling 20,748 hospitalized COVID-19 patients overall were included. A pooled meta-analysis of these studies showed that anticoagulation therapy, compared with non-anticoagulation therapy, was associated with lower mortality risk (RR 0.70, 95% CI 0.52–0.93, p = 0.01). The evidence of benefit was stronger among critically ill COVID-19 patients in the intensive care units (RR 0.59, 95% CI 0.43–0.83, p = 0.002). Additionally, severe bleeding events were not associated with the administration of anticoagulants (RR 0.93, 95% CI 0.71–1.23, p = 0.63).Conclusion: Among patients with COVID-19 admitted to hospital, the administration of anticoagulants was associated with a decreased mortality without increasing the incidence of bleeding events.
Circular Ribonucleic Acid circFTO Promotes Angiogenesis and Impairs Blood–Retinal Barrier Via Targeting the miR-128-3p/Thioredoxin Interacting Protein Axis in Diabetic Retinopathy
Authors: Guo Jianjin , Xiao Feng , Ren Wei , Zhu Yikun , Du Qiujing , Li Qian , Li Xing 
Published: August 2021

Background: Increasing attention has been attracted by the role of circular RNAs (circRNAs) in ocular diseases. Previous study has revealed that circ_0005941 (also known as circFTO, an alpha-ketoglutarate–dependent dioxygenase) was upregulated in the vitreous humor of diabetic retinopathy (DR), while its underlying mechanism in DR remains unknown.Methods: Retinal vascular endothelial cells (RVECs) treated with high glucose (HG) were used to establish the DR cell model. The in vivo assays were conducted using streptozotocin-induced diabetic mice. The circular structure and stability of circFTO were identified by Sanger sequencing and RNase R treatment. RT-qPCR analysis was used to detect the RNA expression. The levels of the mRNA-encoded protein thioredoxin-interacting protein (TXNIP) or angiogenesis-associated proteins (VEGFA, PDGF, and ANG2) and blood–retinal barrier (BRB)-related proteins (ZO-1, Occludin, and Claudin-5) were measured by Western blot. The viability of RVECs was measured using CCK-8 assays. The angiogenesis of RVECs was assessed using tube formation assays in vitro. Endothelial permeability assays were conducted to examine the function of the BRB. The binding between genes was explored using RNA pulldown and luciferase reporter assays.Results: CircFTO was upregulated in HG-treated RVECs. CircFTO deficiency reversed the HG-induced increase in the viability and angiogenesis of RVECs and alleviated HG-mediated impairment of the BRB. MiR-128-3p bound with circFTO and was downregulated in HG-treated RVECs. TXNIP was a downstream target gene of miR-128-3p. TXNIP was highly expressed in the DR cell model. Rescue assays revealed that circFTO promoted angiogenesis and impaired the blood–retinal barrier by upregulating TXNIP. In the DR mouse model, circFTO silencing inhibited angiogenesis and promoted BRB recovery in vivo.Conclusion: CircFTO promotes angiogenesis and impairs the blood–retinal barrier in vitro and in vivo by binding with miR-128-3p to upregulate TXNIP in DR.
Genomic Analysis Reveals Heterogeneity Between Lesions in Synchronous Primary Right-Sided and Left-Sided Colon Cancer
Authors: Hu Hanqing , Zhang Qian , Huang Rui , Gao Zhifeng , Yuan Ziming , Tang Qingchao , Gao Feng , Wang Meng , Zhang Weiyuan , Ma Tianyi , Qiao Tianyu , Jin Yinghu , Wang Guiyu 
Published: August 2021

Background: The synchronous primary right-sided and left-sided colon cancer (sRL-CC) is a peculiar subtype of colorectal cancer. However, the genomic landscape of sRL-CC remains elusive.Methods: Twenty-eight paired tumor samples and their corresponding normal mucosa samples from 14 patients were collected from the Second Affiliated Hospital of Harbin Medical University from 2011 to 2018. The clinical–pathological data were obtained, and whole-exome sequencing was performed based on formalin-fixed and paraffin-embedded samples of these patients, and then, comprehensive bioinformatic analyses were conducted.Results: Both the lesions of sRL-CC presented dissimilar histological grade and differentiation. Based on sequencing data, few overlapping SNV signatures, onco-driver gene mutations, and SMGs were identified. Moreover, the paired lesions harbored a different distribution of copy number variants (CNVs) and loss of heterozygosity. The clonal architecture analysis demonstrated the polyclonal origin of sRL-CC and inter-cancerous heterogeneity between two lesions.Conclusion: Our work provides evidence that lesions of sRL-CC share few overlapping mutational signatures and CNVs, and may originate from different clones.
Differential Effects of Oleuropein and Hydroxytyrosol on Aggregation and Stability of CFTR NBD1-ΔF508 Domain
Authors: Robinson Christopher S. , Wyderko Jennifer A. , Vang Yeng , Martin Galen , Youker Robert T. 
Published: August 2021

Cystic Fibrosis (CF) is caused by loss of function mutations in the Cystic Fibrosis transmembrane conductance regulator (CFTR). The folding and assembly of CFTR is inefficient. Deletion of F508 in the first nucleotide binding domain (NBD1-ΔF508) further disrupts protein stability leading to endoplasmic reticulum retention and proteasomal degradation. Stabilization and prevention of NBD1-ΔF508 aggregation is critical to rescuing the folding and function of the entire CFTR channel. We report that the phenolic compounds Oleuropein and Hydroxytryosol reduce aggregation of NBD1-ΔF508. The NBD1-ΔF508 aggregate size was smaller in the presence of Hydroxytryosol as determined by dynamic light scattering. Neither phenolic compound increased the thermal stability of NBD1-ΔF508 as measured by differential scanning fluorimetry. Interestingly, Hydroxytyrosol inhibited the stabilizing effect of the indole compound BIA, a known stabilizer, on NBD1-ΔF508. Molecular docking studies predicted that Oleuropein preferred to bind in the F1-type core ATP-binding subdomain in NBD1. In contrast, Hydroxytyrosol preferred to bind in the α4/α5/α6 helical bundle of the ABCα subdomain of NBD1 next to the putative binding site for BIA. This result suggests that Hydroxytyrosol interferes with BIA binding, thus providing an explanation for the antagonistic effect on NBD1 stability upon incubation with both compounds. To our knowledge, these studies are the first to explore the effects of these two phenolic compounds on the aggregation and stability of NBD1-ΔF508 domain of CFTR.
Atratividade e qualidade de iscas alimentares na captura da mosca-das-frutas Ceratitis capitata Wiedemann (Diptera: Tephritidae)
Authors: Santo de Souza Mileny dos , Oliveria Robério de , Silva Nunes Gilmar da , Miguel Porcino Mirelly , Vitoriano Dantas Thais Aparecida , Luna Batista Jacinto de 
Published: August 2021

Objetivou-se determinar a eficiência e qualidade de atrativos alimentares na captura de Ceratitis capitata. Avaliou-se a eficiência de dois atrativos alimentares comerciais o Bio Anastrepha® e o CeraTrap® nas formas líquida e semissólida. O delineamento experimental usado foi em blocos casualizados em esquema fatorial (5 x 6 x 2 x 4) sendo: cinco (quatro atrativos + testemunha de água destilada), seis períodos de exposição dos atrativos no ambiente, dois sexos (adultos fêmeas e machos de C. capitata) distribuídos em quatro blocos. Os atrativos foram dispostos no ambiente telado em armadilhas do tipo frasco caça-mosca, onde foram liberados 300 adultos de C. capitata a cada período de exposição. Avaliou-se a atratividade (nº de insetos capturados) e qualidade das iscas alimentares (pH, proteína bruta %, conteúdo evaporado). Os atrativos líquidos capturaram mais C. capitata do que os semissólidos. A maior atratividade ao longo dos seis períodos de exposição foi do atrativo CeraTrap® liquida e a captura de insetos fêmeas foi maior em relação aos machos. O atrativo líquido CeraTrap® é o mais indicado para captura desse díptero.
Trocas gasosas em gravioleira ‘Morada’ sob adubação orgânica e mineral
Authors: Oliveira de Malta Altamiro , Esfrain Pereira Walter , Nóbrega Torres Mariana Neves , Oliveira de Malta Alan , Almeida Medeiros Diego , Alves Dias Jefferson 
Published: August 2021

Trabalhos envolvendo o efeito da adubação orgânica e química sob as trocas gasosas na gravioleira ainda são restritos na literatura científica. Assim, o objetivo deste experimento foi avaliar as trocas gasosas em gravioleira ‘Morada’ sob adubação orgânica e mineral. Foi instalado um experimento em um pomar de gravioleira com 42 meses de idade entre os meses de janeiro a setembro de 2014. O solo foi classificado como Latossolo Amarelo Distrófico. O delineamento experimental foi em blocos casualizados, com sete tratamentos e quatro repetições, com duas plantas por parcela. Os tratamentos utilizados foram: T1= testemunha (sem adubação); T2= adubação mineral (NPK); T3= esterco de bovino; T4= esterco de aves; T5= adubação mineral + esterco de caprino; T6= esterco de aves + 3 kg de pó de rocha; T7= esterco de caprino. As variáveis analisadas foram: concentração interna de CO2, condutância estomática, taxa de transpiração, taxa fotossintética, eficiência de carboxilação e do uso da água. As avaliações foram feitas em campo, após 60 dias da última adubação nitrogenada, no período das 8 às 11 horas. Os dados foram submetidos à análise de variância e ao teste de Tukey. A adubação mineral com NPK proporcionou maior taxa fotossintética e eficiência de carboxilação na gravioleira ‘Morada’. A concentração interna de CO2, condutância estomática, taxa de transpiração e eficiência de uso da água não foram afetadas pelos tratamentos.
Produção de massa seca, volume radicular e eficiência nutricional de fósforo em Brachiaria brizantha cv. Marandu e Massai (Panicum maximum x P. infestum)
Authors: Sodré Fernandes Andre Luis , Brachtvogel Elizeu Luiz , Reis Luis Lessi 
Published: August 2021

Avaliação de respostas de Brachiaria brizantha cv. Marandu e Massai a diferentes doses de fósforo. O ensaio foi conduzido em casa de vegetação no IFMT – Campus Confresa, implantado em vasos plásticos de 5dm-³ com areia grossa lavada. O delineamento experimental em blocos casualizados, combinados em esquema fatorial 5x2, com quatro repetições para cada época de coleta (30 e 60 dias após emergência). Os tratamentos consistiram em aplicações de doses de fósforo (P), via solução nutritiva, correspondentes a concentração de P em solução equivale a 0,0; 36,9; 73,8; 110,8 e 147,6 mg dm-3. Para o material vegetal coletado foi obtida a massa seca em estufa de circulação de ar e posteriormente moídas separadamente (parte aérea e raiz) para a determinação da concentração de fósforo. Os dados foram submetidos à análise de variância a nível de 5% de probabilidade pelo teste F usando software Sisvar. Observando-se efeito significativo para dose, espécie e interação doses e espécie. A espécie Brachiaria revelou-se ser mais eficiente na absorção e transporte do nutriente P do que a espécie Massai, alcançando maior produção de massa seca e raiz, evidenciando ser mais responsiva a adubação fosfatada.
La arqueología histórica, la sociedad, la historia y el estado las relaciones entre la arqueología y antropología urbana
Authors: Volpe Soccorso 
Published: August 2021

El registro arqueológico como sabemos no es indicador directo de las actividades cotidianas, se trata de un registro que generalmente es desechado, abandonado o dejo de ser utilizado o reciclado según sea la condición material de dicho registro. De ahí que se utilizan los conceptos de contextos de deposición y contextos socio-culturales. En este caso analizaremos el correspondiente contexto de deposición del sitio popularmente llamado La Basurita, antiguo Vaciadero de Basuras de la ciudad de Rosario. Si bien en este lugar están los desechos producidos por la ciudad entre los años 1870-1890 en el mismo lugar desde la instalación del Vaciadero una numerosa y anónima población vivió e interactuó con los desperdicios ahí arrojados, produciendo modificaciones en el registro ; que si no tuviéramos en cuenta esta situación podríamos interpretarlos equivocadamente.
Basic life support education: the impact of lecture-demonstration in undergraduate students of health sciences
Authors: Castanha Cyntia , Fernando Barbosa Tavarez Luis , Leone Claudio , Da Silva Paiva Laércio , Elena Guerrero Daboin Blanca , Da Silva Freitas Marques Natália , Zangirolami-Raimundo Juliana , Daminello Raimundo Rodrigo 
Published: August 2021

Background: Cardiopulmonary arrest (CPA) is a severe public health problem and a leading cause of death worldwide. According to the American Heart Association (AHA), basic life support (BLS) is the bedrock for improving people's survival after a cardiac arrest, and cardiopulmonary resuscitation is crucial. Through scientific evidence, empowering health professionals focuses on education in resuscitation is vital to identify and attend a CPA victim. In Brazil, there is a lack of data that evaluates the BLS knowledge of health science students. This study analyzed the knowledge retention of medicine, nursing, and physiotherapy students after one year of having a lecture-demonstration on BLS.
Method: Longitudinal study. Undergraduate students of health science participated in the data collection and answered a questionnaire based on BLS following AHA guidelines. Data were collected during two consecutive years, in three different moments (an assessment, a test after a lecture, and an assessment test one year later).
Results: The group improved its score after the class on BLS; the number of correct answers doubled (p <0.001); however, one year later, that score decreased significantly (p <0.001).
Conclusion: No retention of knowledge in health sciences students after a year of a lecture-demonstration on BLS.