bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical analysis on the time-varying temperature field distribution patterns of ballastless track steel-concrete composite box girders at ambient temperature based on field measurements
Authors: Wen Wangqing , Li Shiwei , Yan Aiguo , Zeng Jiahua 
Published: May 2021

AbstractTo analyze the time-varying temperature field distribution pattern of ballastless track steel-concrete composite box girders for a high-speed railway at ambient temperature, a numerical model for analyzing the time-varying temperature field of steel-concrete composite box girders was established based on the long-term monitoring data for the internal and external environments of the main girder of the Ganjiang Bridge on the Nanchang-Ganzhou high-speed railway. The influence of factors such as the deck pavement and the ambient wind speed on the time-varying temperature field of the steel-concrete composite box girders were considered. The results showed that there was a significant difference in the vertical temperature gradient patterns on sections at the side web and at the middle web at the same moment in time due to the hindering effect of the track board on the heat exchange between the ambient temperature and the main girder. Increasing the wind speed accelerated the rate of heat exchange between the main girder surface and the environment. In particular, when the internal temperature of the girder was higher than the ambient temperature, the higher the wind speed was, the larger the temperature gradient was. This study lays a foundation for accurate analysis of the structural response of ballastless track steel-concrete composite girder bridges at ambient temperature.
Models of care in forensic psychiatry
Authors: Kennedy Harry G. 
Published: May 2021

SUMMARYForensic psychiatry services have grown and become more complex in structures, processes and pathways. Legacy customs, practices and changing policy are now organised into formal models of care. These are written accounts of how a health service is delivered, outlining best practice and services for patients progressing through the stages of their condition and the care and treatment available. This article explores the four key elements of a model of care: goals; pathways and processes; treatment programmes; and systematic evaluation. It describes the most common model of care in forensic services, which builds on structures of stratified therapeutic security. It also considers variations on this basic or standard model matched to needs arising from the complex interrelationship with other parts of the mental health service for the population served and with criminal justice, primary care and physical health, housing and welfare agencies.
Mother–infant interaction in women with depression in pregnancy and in women with a history of depression: the Psychiatry Research and Motherhood – Depression (PRAM-D) study
Authors: Bind Rebecca H. , Biaggi Alessandra , Bairead Aoife , Du Preez Andrea , Hazelgrove Katie , Waites Freddie , Conroy Susan , Dazzan Paola , Osborne Sarah , Pawlby Susan , Sethna Vaheshta , Pariante Carmine M. 
Published: May 2021

BackgroundLittle is known about the effects of depression before birth on the quality of the mother–infant interaction.AimsTo understand whether depression, either in pregnancy or in lifetime before pregnancy, disrupts postnatal mother–infant interactions.MethodWe recruited 131 pregnant women (51 healthy, 52 with major depressive disorder (MDD) in pregnancy, 28 with a history of MDD but healthy pregnancy), at 25 weeks’ gestation. MDD was confirmed with the Structured Clinical Interview for DSM-IV Disorders. Neonatal behaviour was assessed at 6 days with the Neonatal Behavioural Assessment Scale, and mother–infant interaction was assessed at 8 weeks and 12 months with the Crittenden CARE-Index.ResultsAt 8 weeks and 12 months, dyads in the depression and history-only groups displayed a reduced quality of interaction compared with healthy dyads. Specifically, at 8 weeks, 62% in the depression group and 56% in the history-only group scored in the lowest category of dyadic synchrony (suggesting therapeutic interventions are needed), compared with 37% in the healthy group (P= 0.041); 48% and 32%, respectively, scored the same at 12 months, compared with 14% in the healthy group (P= 0.003). At 6 days, neonates in the depression and history-only groups exhibited decreased social-interactive behaviour, which, together with maternal socioeconomic difficulties, was also predictive of interaction quality, whereas postnatal depression was not.ConclusionsBoth antenatal depression and a lifetime history of depression are associated with a decreased quality of mother–infant interaction, irrespective of postnatal depression. Clinicians should be aware of this, as pregnancy provides an opportunity for identification and intervention to support the developing relationship.
Sugammadex Versus Neostigmine for Reversal of Rocuronium Neuromuscular Block in Patients Having Catheter-Based Neurointerventional Procedures: A Randomized Trial
Authors: Farag Ehab , Rivas Eva , Bravo Mauro , Hussain Shazam , Argalious Maged , Khanna Sandeep , Seif John , Pu Xuan , Mao Guangmei , Bain Mark , Elgabaly Mohamed , Esa Wael Ali Sakr , Sessler Daniel I. 
Published: May 2021

BACKGROUND:
Catheter-based endovascular neurointerventions require deep neuromuscular blocks during the procedure and rapid subsequent recovery of strength to facilitate neurological evaluation. We tested the primary hypothesis that sugammadex reverses deep neuromuscular blocks faster than neostigmine reverses moderate neuromuscular blocks.

METHODS:
Patients having catheter-based cerebral neurointerventional procedures were randomized to: (1) deep rocuronium neuromuscular block with posttetanic count 1 to 2 and 4-mg/kg sugammadex as the reversal agent or (2) moderate rocuronium neuromuscular block with train-of-four (TOF) count 1 during the procedure and neuromuscular reversal with 0.07-mg/kg neostigmine to a maximum of 5 mg. Recovery of diaphragmatic function was assessed by ultrasound at baseline before the procedure and 90 minutes thereafter. The primary outcome—time to reach a TOF ratio ≥0.9 after administration of the designated reversal agent—was analyzed with a log-rank test. Secondary outcomes included time to successful tracheal extubation and the difference between postoperative and preoperative diaphragmatic contraction speed and distance.

RESULTS:
Thirty-five patients were randomized to sugammadex and 33 to neostigmine. Baseline characteristics and surgical factors were well balanced. The median time to reach TOF ratio ≥0.9 was 3 minutes (95% confidence interval [CI], 2-3 minutes) in patients given sugammadex versus 8 minutes (95% CI, 6-10 minutes) in patients given neostigmine. Sugammadex was significantly faster by a median of 5 minutes (95% CI, 3-6 minutes; P < .001). However, times to tracheal extubation and diaphragmatic function at 90 minutes did not differ significantly.

CONCLUSIONS:
Sugammadex reversed deep rocuronium neuromuscular blocks considerably faster than neostigmine reversed moderate neuromuscular blocks. However, times to extubation did not differ significantly, apparently because extubation was largely determined by the time required for awaking from general anesthesia and because clinicians were willing to extubate before full neuromuscular recovery. Sugammadex may nonetheless be preferable to procedures that require a deep neuromuscular block and rapid recovery.
Afterword: The Littoral Museum of the Twenty-First Century
Authors: Cadieu Morgane 
Published: May 2021

AbstractThe museum, the mausoleum, and the memorial are key concepts for theorizing beaches and ports in twenty-first-century literature and cinema. On the littoral, these constructions suggest the very opposite of a sealed off monumentality to become living museums of women’s labor in modern and contemporary France (Sciamma, Varda), bodily mausolea of migration on the Senegalese shoreline (Diop), and shapeshifting war memorials in Atlantic and Pacific tidelands (Darrieussecq, Rolin, Virilio). Examples of anamorphic seascapes, especially in photography, underscore the reversibility of sand and cement in Japan (Narahashi, Ono), as well as the dereliction of Cuban beach architecture and American industrial harbors (Morales, Sekula). In art as in criticism, the waterfront stages gender and class crossings (Dumont) and tangles fields. The afterword thereby weaves the major threads of the special issue: textures, labor, and ruins; social mobility and migration; marine life, geological time, and the history of sensation.
Postoperative Complications and Long-Term Quality of Life After Multimodality Treatment for Esophageal Cancer: An Analysis of the Prospective Observational Cohort Study of Esophageal-Gastric Cancer Patients (POCOP)
Authors: Jezerskyte E. , van Berge Henegouwen M. I. , van Laarhoven H. W. M. , van Kleef J. J. , Eshuis W. J. , Heisterkamp J. , Hartgrink H. H. , Rosman C. , van Hillegersberg R. , Hulshof M. C. C. M. , Sprangers M. A. G. , Gisbertz S. S. ,   on behalf of the Dutch UpperGI Cancer Group
Published: May 2021

Abstract
Background
Esophagectomy has major effects on health-related quality of life (HR-QoL). Postoperative complications might contribute to a decreased HR-QOL. This population-based study aimed to investigate the difference in HR-QoL between patients with and without complications after esophagectomy for cancer.

Methods
A prospective comparative cohort study was performed with data from the Netherlands Cancer Registry (NCR) and Prospective Observational Cohort Study of Esophageal-Gastric Cancer Patients (POCOP). All patients with esophageal and gastroesophageal junction (GEJ) cancer after esophagectomy in the period 2015–2018 were enrolled. The study investigated HR-QoL at baseline, then 3, 6, 9, 12, 18, and 24 months postoperatively, comparing patients with and without complications as well as with and without anastomotic leakage.

Results
The 486 enrolled patients comprised 270 patients with complications and 216 patients without complications. Significantly more patients with complications had comorbidities (69.6% vs 57.3%; p = 0.001). No significant difference in HR-QoL was found over time between the patients with and without complications. In both groups, a significant decline in short-term HR-QoL was found in various HR-QoL domains, which were restored to the baseline level during the 12-month follow-up period. No significant difference was found in HR-QoL between the patients with and without anastomotic leakage. The patients with grades 2 and 3 anastomotic leakage reported significantly more “choking when swallowing” at 6 months (ß = 14.5; 95% confidence interval [CI], − 24.833 to − 4.202; p = 0.049), 9 months (ß = 22.4, 95% CI, − 34.259 to − 10.591; p = 0.007), and 24 months (ß = 24.6; 95% CI, − 39.494 to − 9.727; p = 0.007) than the patients with grade 1 or no anastomotic leakage.

Conclusion
In general, postoperative complications were not associated with decreased short- or long-term HR-QoL for patients after esophagectomy for esophageal or GEJ cancer. The temporary decrease in HR-QoL likely is related to the nature of esophagectomy and reconstruction itself.
The role of single nucleotide polymorphisms of IL-1A -889C>T (rs1800587), TNF-A -238G>A (rs361525), and VDR TaqI (rs731236) on susceptibility to herniated nucleus pulposus
Authors: Azharuddin Azharuddin , Ilmawan Muhammad , Fajar Jonny Karunia , Fahriani Marhami , Mamada Sukamto S. , Maliga Helnida Anggun , Nainu Firzan , Dhama Kuldeep , Harapan Harapan , Magetsari Rahadyan 
Published: May 2021

Background: The objective of this study was to determine the role of single nucleotide polymorphisms (SNPs) in interleukin 1 alpha (IL-1A), tumor necrosis factor-alpha (TNF-A), and vitamin D receptor (VDR) genes on the susceptibility to herniated nucleus pulposus (HNP). Methods: Four databases (PubMed, Embase, Cochrane, and Web of Science) were searched as of April 1st, 2021. Authors, publication year, targeted genes, genotype and allele frequency in each case and control groups were collected. Newcastle-Ottawa scale was used to evaluate the publication quality. The pooled estimates of association of IL-1A -889C>T (rs1800587), TNF-A -238G>A (rs361525), and VDR TaqI (rs731236) and susceptibility to HNP were assessed using Z test and presented as odd ratio (OR) and 95% confidence intervals (95%CI). Results: We screened 3,067 unique studies for eligibility and three, two and nine studies on IL-1A -889C>T, TNF-A -238G>A, and VDR TaqI were included, respectively, in our meta-analysis. The studies consisting 369 HNP cases and 433 controls for IL-1A -889C>T, 252 cases and 259 controls for TNF-A -238G>A and 1130 cases and 2096 controls for VDR TaqI. Our pooled estimates indicated that there was no significant association of those SNPs with the susceptibility to HNP in any genotype, dominant model, recessive model, or allele comparations. Conclusion: Although individual studies suggested the important role of gene expression dysregulation associated with SNPs in IL-1A, TNF-A, and VDR, our data indicated that IL-1A -889C>T, TNF-A -238G>A, and VDR TaqI had weak association with HNP susceptibility in both genotypes and allele distributions. However, since heterogeneity was identified among studies included in this meta-analysis, further meta-analysis with a larger population and subgroup analysis on specific population are warranted to support this finding.
СТРАТЕГИЧЕСКОЕ РАЗВИТИЕ ТРАНСПОРТНОЙ СИСТЕМЫ КИТАЯ
Authors: Wang Xiugang , Lysochenko Alla A. 
Published: May 2021

В последние годы, с быстрым социально-экономическим развитием Китая и ускорением процесса городского строительства, современная транспортная экономика как важная часть экономики в сфере услуг, стала основой национального экономического развития. Однако ряд проблем, таких как неравномерное развитие региональных перевозок, низкое качество транспортных услуг, ограничения внешних ресурсов требует разработку стратегии направленной на устойчивое развитие транспортной экономики.
Целью исследования статьи является анализ современной транспортной системы Китая и формирование предложений по дальнейшему ее стратегическому развитию.
Метод проведения работы: поставленная цель предопределила необходимость использования ряда подходов и приемов, обеспечивающих комплексный анализ и применение системно-функционального метода исследования. В его рамках использовались такие приемы как сравнительный анализ, факторный анализ, статистическое прогнозирование.
Результаты: представлены предложения по оптимизации транспортной структуры и осуществление комплексных стратегических корректировок транспортной системы; развитию системы уровня управления транспортной экономикой интенсивным путем, а также внедрения передовых технологий и создание интеллектуальной современной системы управления экономикой на транспорте.
Область применения результатов: полученные результаты целесообразно применять при разработке стратегии в транспортной сфере Китая как обобщенной модели и точечном определении развития категорий транспорта.
An Overlapping Case of Miller Fisher Syndrome and the Pharyngeal-Cervical-Brachial Variant of Guillain-Barré Syndrome
Authors: Hélio Martins  , Joana Mendonça  , David Paiva  , Carlos Fernandes  , Jorge Cotter  
Published: May 2021

A 55 years-old Caucasian male presented initially in the emergency room reporting myalgia, chills and fever. Physical exam and laboratory tests were unremarkable and he was discharged with symptomatic care. He returned to our ER two weeks later reporting dizziness, loss of balance, blurred vision, mild dysarthria and bilateral hand paresthesia. On examination he presented complete bilateral ophthalmoplegia, mild dysarthria, left finger-to-nose dysmetria, ataxia, areflexia and bilateral hand hypoesthesia without fever. Blood tests and head computed tomography were normal. The patient was admitted to the Internal Medicine department. On second day inwards the patient presented dysphagia. Head magnetic resonance angiogram showed no signs of ischemia or vascular disease and a lumbar puncture was performed but no pleocytosis, albumin-cytological dissociation or hypoglycorrhachia was present. Despite the normal results we suspected of a Guillain–Barré syndrome variant, and started treatment with intravenous immunoglobulin (IVIG) in a dose of 400mg per kilogram and continued for five days with immediate neurological improvement. We present a rare overlapping case of Miller Fisher syndrome and Pharyngeal-Cervical-Brachial variant of Guillain–Barré syndrome.
Bilateral Decompressive Craniectomy in Malignant Cerebral Venous Thrombosis
Authors: Eduardo Soriano-Navarro  , Vanessa Cano-Nigenda  , Fernanda Menéndez-Manjarrez  , Esmirna Farington-Terrero  , Juan José Méndez-Gallardo  , Alejandro García-Irigoyen  , Antonio Arauz  
Published: May 2021

Introduction: Despite the extremely favourable prognosis of patients with cerebral venous thrombosis (CVT), death occurs in 10–15% of patients. In severe cases of malignant CVT with supratentorial haemorrhagic lesions, cerebral oedema and brain herniation, decompressive surgery may be the only life-saving treatment. Patient and methods: We present the case of a puerperal young woman with progressive headache, seizures and decreased alertness. Thrombosis of the entire superior sagittal sinus with bifrontal venous infarcts and midline shift was confirmed by magnetic resonance imaging with venography sequencing. Despite medical treatment with anticoagulation, progressive neurological deterioration was observed, so bilateral, frontal decompressive craniectomy was performed. Results: At the 6-month follow-up, we observed partial functional recovery with a modified Rankin score of 3. Discussion: Bilateral decompressive craniectomy may be a life-saving therapeutic option when medical therapy fails and there are clinical and radiological features of progression in both cerebral hemispheres.
Infectious Mononucleosis Resulting in Acute Necrotizing Mediastinitis: A Case Report and Literature Review
Authors: Héloïse Van Noten  , Samuel Markowicz  , Serge Cappeliez  , Soraya Cherifi  
Published: May 2021

The serological prevalence of Epstein-Barr virus (EBV) among young adults exceeds 90% worldwide. Even though EBV primary infection is usually benign, severe complications can occur in adolescents and young adults and so the disease must be promptly diagnosed. The development of an oropharyngeal abscess leading to a descending necrotizing mediastinitis (DNM) is exceptional and potentially lethal, so early diagnosis with a CT scan, appropriate antibiotics and surgery are essential. The authors present a case where DNM was associated with reactive hemophagocytic syndrome as a result of infectious mononucleosis, as well as a review of similar cases in the English literature.
Kawasaki-like Syndrome as an Emerging Complication of SARS-CoV-2 Infection in Young Adults
Authors: César Burgi Vieira  , Ana Teresa Ferreira  , Filipa Botelho Cardoso  , Jorge Pelicano Paulos  , Nuno Germano  
Published: May 2021

Background: Kawasaki-like syndrome occurring in children during the COVID-19 pandemic has been labelled multisystem inflammatory syndrome in children (MIS-C) by the CDC and paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 infection (PIMS-TS) by the ECDC. Case report: We report the case of an 18-year-old male patient presenting with a 72-hour history of abdominal pain, fever, erythematous skin rash, vomiting and diarrhoea. Examination showed he also had shock and he was first thought to have oedematous cholecystitis. SARS-CoV-2 infection was also diagnosed. He was admitted to the ICU, and echocardiography showed cardiac dysfunction, with a low ejection fraction and low cardiac index. High-sensitivity troponin serum levels were elevated. The patient received inotropic and vasopressor support. As he fulfilled several criteria for MIS-C/PIMS-TS, he was administered acetylsalicylic acid, corticosteroids and immunoglobulin, with a good clinical response.<br /> Conclusion: This case emphasizes how this severe presentation of COVID-19 can easily be misdiagnosed if the clinician is less aware of this syndrome in younger patients.
Jaikoa regua
Authors: De Araújo Inês , Queiroz Tania , Karai Mirim Laércio 
Published: May 2021

Kova´e nhembopara ma ijayu ha´e ombopara Xadalu Tupã Jekupe pe omboyau ague kova´emba´eapo ojapo va´e kue kuery, omombe´u mba´eixa pa guembiapo arte regua re ha´e oiko oikoa tetã re ha´e tekoa rupi ha´e maba´eixa vy pa omovaen rã o arte amboae kuery pe, ha´e javive pe oupity aguã rami ojepy´a py rei he´yn re, ha´e javive pe omovaen aguã rami.
Wellenreiten im Gesundheitsamt – Digitaler Wandel im Corona-Containment
Authors: Zimmermann Roland , Zimmermann Ina , Bornschlegl Philipp , Günther Katja 
Published: May 2021

ZusammenfassungDas „Brechen von Infektionsketten“ ist das Ziel für den Öffentlichen Gesundheitsdienst (ÖGD) in der Pandemiebekämpfung. Diese komplexe Aufgabe benötigt digitale Unterstützung in den Gesundheitsämtern. Entgegen der landläufigen Meinung ist in den meisten Fällen dafür geeignete Software schon seit Sommer 2020 verfügbar – allerdings als nicht-standardisierte, lokale Lösungen. Viel entscheidender für die Zielerreichung ist es, die richtige Arbeitsteilung und die dazu passenden Prozesse zu definieren sowie ein enges Controlling des Kontaktmanagements zu realisieren. Erst dadurch können in kurzer Zeit viele Unterstützer in den Ämtern entsprechend der Pandemiesituation zusätzlich produktiv eingesetzt werden. In dem vorliegenden Erfahrungsbericht wird anhand eines Fallbeispiels des Gesundheitsamtes der Stadt Nürnberg aufgezeigt, wie Prozessorganisation, IT und Controlling aufeinander abgestimmt werden sollten. Diese Erkenntnisse helfen auch bei der anstehenden Vernetzung der föderal strukturierten Gesundheitsämter in Deutschland über eine zentrale Lösung (SORMAS). Denn es zeigt sich, dass lediglich die politische Vorgabe zentraler Lösungen noch lange nicht zu ihrer effektiven Nutzbarkeit führt und wiederum der Zusammenhang aus Software und Organisation berücksichtigt werden muss, um nicht Schiffbruch zu erleiden.
Identifying barriers to early presentation in patients with locally advanced breast cancer (LABC) in Northern Singapore: Qualitative study
Authors: Ng Ding Yi , Tudor Car Lorraine , Ng Marcus Jia Ming , Lu Junde , Leung Joelle , Goo Tiong Thye , Chia Clement Luck Khng 
Published: May 2021

Introduction
Breast cancer is the leading cause of death in Singaporean women, with advanced stage rendering a poorer prognosis. This study aims to explore the barriers to early presentation, information needs and sources in patients with locally advanced breast cancer (LABC).

Materials & methods
A convenience sample of patients who presented with locally advanced breast cancer to the Department of General Surgery in a teaching tertiary hospital were recruited for the study. We conducted semi-structured interviews face to face with the recruited patients. We recorded the interviews, transcribed them verbatim and analysed using thematic content analysis.

Results
Twenty-three participants were recruited of which 12 were Chinese and 11 were Malay women. Mean age was 60 years (± 13 SD). The most common knowledge barrier resulting in delay was the misconception that a breast lump must be painful to be malignant. Other knowledge barriers include the lack of knowledge and misinformation from the internet or other social media platforms. Some perceived barriers include fear of diagnosis, fear of treatment and fear of imposing financial burden on family members. A significant proportion of participants were also not aware of a national breast screening programme.

Conclusions
Our study has found that barriers to early presentation of women with locally advanced breast cancer remain similar and have persisted over the years despite targeted efforts. There is a need for a rethink of existing strategies and to develop new innovative ways to reach out to this group of patients.