bluuebunny/crossref_metadata_2025_split huggingface dataset:
The duration and specificity of the humoral immune response to SARS-CoV-2
Authors: Dubrovskyi E. I. , Dons’koi B. V. 
Published: September 2021

Background. Our assumption that immunity after COVID-19 will persist has been fully confirmed in the researches already conducted. Our work is a continuation of research that demonstrates the results obtained 12 months of determining the humoral response in patients after COVID-19.
Materials and methods. The research involved 42 individuals. All subjects had a positive PCR test for COVID-19. At certain intervals, from 40 to 240 days, individuals in the group were tested for IgG SARS-CoV-2. The last step was to check the level of IgG to the COVID-19 nucleocapsid and spike protein in the research group for 360 days from the onset of the disease. A private certified laboratory in Kyiv, the “DNA Laboratory”, was involved. Patients were tested for antibodies to COVID-19 by ELISA using serology COVID-19 test systems VitroTest (Ukraine). The immunological laboratory of the Institute of Pediatrics, Obstetrics and Gynecology was used in parallel for interlaboratory quality control. The results of the research coincided.
Results. The level of class G immunoglobulins to nucleocapsid in the subjects has gradually decreased over 8 months. It is noteworthy that in the period from 40 to 150 days in all 42 patients (100 %) antibodies did not disappear. Decreasing of antibodies occurred between 150 and 240 days. However, the data obtained for 360 days significantly changed the picture. In a certain part of the subjects, who had low or even negative levels of antibodies for 8 months, as of 12 months, the level of immunoglobulin (Ig) class G again rose above the threshold value. Thus, we see that from the group of 42 people 92.8 % have positive antibodies to the nucleocapsid, and 7.2 %.
Conclusions. The data obtained illustrate that in the study group within 12 months after SARS-CoV-2, the vast majority of individuals remain with specific antibodies to the nucleocapsid and spike-protein.
Egypt’s tourism industry facing global challenges: from the Arab spring to the pandemic
Authors: Elkina Ekaterina A. 
Published: September 2021

In the article, the author examines the status of Egypt&apos;s tourism industry in 2011-2021. The critical importance of tourism is that this industry is one of the two main sources of foreign exchange in the country, along with income from the Suez Canal. A downturn in the tourism industry automatically threatens the existence of several million as jobs.
The author identifies 3 critical points from which a sharp drop begins. The first point is the winter of 2010-2011. The unrest of the &quot;Arab Spring&quot; was accompanied by the leakage of large funds from the country, social chaos, and a decrease in the general level of security, which could not but frighten potential tourists. The next key point of the fall of the tourism industry in Egypt is the death of all passengers in the crash over the Sinai Peninsula of a Russian plane flying on the Sharm el-Sheikh - St. Petersburg route, and the subsequent complete ban on flights between Russia and Egypt.
The third critical point was the beginning of the pandemic caused by COVID-19, officially announced by WHO on March 11, 2020, and, as a result, the almost complete closure of borders.
Based on the analysis of statistical data from Egyptian and Western European sources, it is concluded that the indicators of the Egyptian tourism industry reflect both the trajectory of the country&apos;s political state and its almost complete dependence on the global health situation. It also concludes that the industry is extremely fragile, and the decision to partially reorient the industry towards domestic tourism, as well as receiving guests from neighboring Arab states, made in the period between the Arab Spring and the pandemic, was correct.
Security issues in the Middle East: the present challenges and threats
Authors: Werfelli Wissal 
Published: September 2021

The article analyzes the issue of the Middle East security. The Arab countries are facing a lot of regional threats and a fundamental shift in the regional security system, which has become one of the basic variables for the Middle East through the transition to a new form of regional and international interactions. The existence of mutual influences between the nature of the international system and the regional order of the Middle East and the Gulf region is already considered as an incubator for all intractable conflicts and crises.
We cannot study the concept of regional security in separate from the global effects and repercussions. After the end of the Cold War and after the collapse of the Soviet Union in 1991, the structural transformations and global changes led to the emergence of profound changes in the international system, which resulted in the restructuring of the general features of the international environment.
The international transformation is marked by the fact that the new world order increased the chances of emergence of new international powers in both Europe and Asia, whether countries or major economic or political blocs trying to establish a multi-polar international order, which prompted the United States to pursue a policy of cooperation with competing powers.
And in light of this international environment, it was natural for the regions of strategic importance, particularly the Middle East, to be affected because they were linked to relations of mutual influence with the international system, as international balances affect regional balances.
Studies on Canopy Parameters of Some Mangroves Along the Coast of Maharashtra
Authors: Kulkarni Narendra , Bhosale Leela J. 
Published: September 2021

Mangrove species, viz., Avicennia officinalis, Avicennia marina var. acutissima, Avicennia marina (dwarf), Rhizophora mucronata, Sonneratia alba, Aegiceras corniculatum, Kandelia candel were chosen for measurement of height of the tree and girth or circumference. The sampling was random and at least 50 records were made. The girth is measured by the tape. The measurement of the height is made with the help of abny level. The Tables 1 to 8 records the values for girth, height and canopy cover as well as for correlation coefficient (r). There correlation between girth and canopy in all the species studied however in case of Avicennia officinalis and Aegiceras corniculatum girth and height show more co-relation than girth and C. cover. The positive co-relation observed between girth and canopy is more or less 0.7 except Avicennia marina (dwarf) Excoecaria agallocha and Aegiceras corniculatum. The co-relation is observed in girth and height is difficult to explain. This case is observed in Avicennia officinalis and Aegiceras corniculatum.
Field Observations During the Second Microwave Water and Energy Balance Experiment (MicroWEX-2): from March 17 through June 3, 2004
Authors: Judge Jasmeet , Casanova Joaquin , Lin Tzu-yun , Tien Kai-Jen Calvin , Jang Mi-young , Lanni Orlando , Miller Larry 
Published: September 2021

The goal of MicroWEX-2 was to understand the land-atmosphere interactions during the growing season of corn, and their effect on observed microwave brightness signatures at 6.7 GHz, matching that of the satellite-based microwave radiometer, AMSR. This document is Circular 1480, one of a series of the Department of Agricultural and Biological Engineering, UF/IFAS Extension. Original publication date November 2005.
CIR1480/AE360: Field Observations During the Second Microwave Water and Energy Balance Experiment (MicroWEX-2): from March 17 through June 3, 2004 (ufl.edu)
Renter Power for Better Living: Introduction
Authors: Harrison Mary N. 
Published: September 2021

Information in this book will help you protect the health of your family and your financial well-being. It will teach you to care for your home and make it a better place to live. This document is FCS5230-02, one of a series of the Family Youth and Community Sciences Department, UF/IFAS Extension. Original publication date June 2002. Revised December 2005.
Keeping it Clean: A Healthy House
Authors: Harrison Mary N. 
Published: September 2021

The way you keep your home will affect the health of your family and especially of your children. The number of children with asthma is increasing. You can help make your home a safe and healthy place for your children by eliminating or controlling the risks outlined in this publication. This document is FCS5232-01, one of a series of the Family Youth and Community Sciences Department, UF/IFAS Extension. Original publication date June 2002. Revised December 2006.
FCS5232-01/FY786: Keeping It Clean: A Healthy House (ufl.edu)
Keeping it Clean: Cleaning Bathrooms, Sink, Bathtub, Shower, Toilet
Authors: Harrison Mary N. 
Published: September 2021

Every family member can help keep the bathroom clean and in good condition. Some chores need to be done daily, others weekly. This document is FCS5232-04, one of a series of the Family Youth and Community Sciences Department, UF/IFAS Extension. Original publication date June 2002. Revised December 2005.
Keeping it Safe: Home and Personal Safety, Fire Extinguishers, Smoke Detectors, Ground Fault Circuit Interrupters, Carbon Monoxide Detectors
Authors: Harrison Mary N. 
Published: September 2021

There are several items that you should have to protect your family and home, such as: a fire extinguisher, smoke detectors, Ground Fault Circuit Interrupters (GFCIs), carbon monoxide detectors, and locks on your doors and windows. This document is FCS5233-05, one of a series of the Department of Family, Youth and Community Sciences, UF/IFAS Extension. Original publication date: May 2002. Revised: December 2005.
Ciruelas en Florida
Authors: Phillips Richard L. , Campbell Carl W. , Balerdi Carlos F. , Crane Jonathan H. 
Published: September 2021

Este documento, HS1028, es uno de una serie de publicaciones del Horticultural Sciences, Servicio de Extensión Cooperativa de la Florida, Instituto de Alimentos y Ciencias Agrícolas, Universidad de la Florida. (UF/IFAS). Fecha de primera publicación: Octubre 1993. Repasado Octubre 2005.
HS1028/HS272: Las Ciruelas en Florida (ufl.edu)
Aguacate en Florida
Authors: Crane Jonathan H. , Balerdi Carlos F. 
Published: September 2021

Este documento, HS1039, es uno de una serie de publicaciones del Horticultural Sciences, Servicio de Extensión Cooperativa de la Florida, Instituto de Alimentos y Ciencias Agrícolas, Universidad de la Florida. (UF/IFAS). Fecha de primera publicación: abril 1966. Repasado octubre 2005.
HS1039/HS284: El Aguacate en Florida (ufl.edu)
Mamey Sapote en Florida
Authors: Balerdi Carlos F. , Crane Jonathan H. 
Published: September 2021

Este documento, HS1040 (FC-30), es uno de una serie de publicaciones del Departamento de Horticultural Sciences, Servicio de Extensión Cooperativa de la Florida, Instituto de Alimentos y Ciencias Agrícolas, Universidad de la Florida. (UF/IUFAS). Fecha de primera publicación: octubre 1979. Repasado octubre 28, 2005.
HS1040/HS285: El Mamey Sapote en Florida (ufl.edu)
Field Key to Identification of Scale Insects on Holly (Ilex spp.)
Authors: Gyeltshen Jamba , Hodges Amanda C. 
Published: September 2021

Over 500 different varieties of hollies (Ilex spp) are grown in the US as hedges, garden borders, and specimen plants. A well managed planting is generally free of pests and diseases but when growing conditions are poor, pest and disease can become a problem (Ingram and Barrick 2003). This document is IPM-141 (IN649), one of a series of the Entomology and Nematology Department, UF/IFAS Extension. First published: January 2006.
Pesticide Labeling: Environmental Hazards Statements
Authors: Fishel Frederick M. 
Published: September 2021

This document explains environmental hazard statements seen on pesticide labels and discusses the toxicity criteria used in determining the manner in which they are presented on the pesticide label. Examples of typical statements regarding environmental hazards found on pesticide labels are provided. This document is PI-99, one of a series of the Agronomy Department, UF/IFAS Extension. Original publication date February 2006.
PI-99/PI136: Pesticide Labeling: Environmental Hazards Statements (ufl.edu)
Pesticide Toxicity Profile: Triazine Pesticides
Authors: Fishel Frederick M. 
Published: September 2021

This document provides a general overview of human toxicity, provides a listing of laboratory animal and wildlife toxicities and a cross reference of chemical, common and trade names of triazine pesticides registered for use in Florida. This document is PI-121, one of a series of the Agronomy Department, UF/IFAS Extension. Original publication date April 2006.
PI-121/PI158: Pesticide Toxicity Profile: Triazine Pesticides (ufl.edu)
Management of Soil and Water for Vegetable Production in Southwest Florida
Authors: Muchovej Rosa M. , Hanlon Edward A. , McAvoy Eugene , Ozores-Hampton Monica , Roka Fritz M. , Shukla Sanjay , Yamataki H. , Cushman Kent 
Published: September 2021

This document integrates information that was presented at the Sand Land Workshop, 2003, dealing with vegetable production on mineral soils of southwest Florida. The intent of this document is to review those challenges facing vegetable growers dealing with soils, water management, and nutrients. Certain available strategies are evolving to efficiently produce vegetables in southwest Florida on variable mineral soils and are reviewed herein. This document is SL-233, one of a series of the Department of Soil and Water Sciences, UF/IFAS Extension. Original publication date October 2005.
SL-233/SS452: Management of Soil and Water for Vegetable Production in Southwest Florida (ufl.edu)
Preventing Encounters between Children and Snakes
Authors: Johnson Steve A. , Main Martin B. 
Published: September 2021

The most effective way to prevent a child from being bitten by a venomous snake at school or elsewhere is to prevent them from interacting with a snake. We provide measures that can be taken by schools to discourage snakes from coming onto school property and we provide a short educational program that teachers can give to students. This document is WEC 201, one of a 4-part series of the Department of Wildlife Ecology and Conservation entitled Dealing with Venomous Snakes in Florida School Yards, UF/IFAS Extension. Original publication date September 2005.
WEC 201/UW227: Preventing Encounters between Children and Snakes (ufl.edu)
Analisis Tingkat Kapabilitas Knowledge Management System Information Menggunakan Model Framework Cobit 5 (Studi Kasus Hotel XYZ)
Authors: Firmansyah Muhamad Dody 
Published: September 2021

Abstract - Knowledge Management System (KMS) to improve the quality of human resources in an organization by improving communication among employees and to increase skill by transferring knowledge. Knowledge Management System (KMS) is one of many ways to foster a culture of knowledge sharing among individuals and organizations. In this research, the researcher tries to develop a model of knowledge management system suitable for existing condition at the Hotel XYZ run effectively, it is necessary to conduct an evaluation activity by examining the process of managing knowledge possessed by each individual can be transferred to other individuals through the process of knowledge sharing and knowledge presentation management and through Effective management of knowledge is expected to be maintained well so that it can provide benefits to the company. KMS (Knowledge Management System) is main tool for implementation of existing processes in the knowledge management , is necessary to do an analysis to find out the extent of the processes of knowledge level management found in Hotel XYZ at the maturity level of KMS (Knowledge Management System) it affects the performance of employees, the results of the analysis can be expected to be an evaluation material that will have an impact on the company.
Trend Information System Research Topics in the SINTA Journal for the Period 2015-2019
Authors: Muniroh Lailatul , Rolliawati Dwi , Amrozi Yusuf 
Published: September 2021

Information systems discipline has developed rapidly over time. Based on 533 information systems study programs in Indonesia, it is possible to have a variety of information systems research topics. However, there is no research on information system topic trends in Indonesia. So, this research aims to determine the trend of research topics in the field of information systems in Indonesia in 2015-2019 based on the publication of the journal SINTA. The method used is qualitative non-interactive. Based on the analysis of documents on the results of data collection on the Google Scholar database using the Publish or Perish tools, the research adopted the recommended PRISMA in improving the quality of systematic reviews and better readers' understanding. The determination of the research topic was based on the abstract content, keywords and referred to the IS ACM Curricula and previous research. The results of this study can be used as academic references in gaining new insights into the field of information systems. The results of the study based on 1917 raw data obtained from data collection in the journal publication SINTA 2, SINTA 3, and SINTA 4 showed that the topic "Application Development" was a trending topic with the highest percentage, namely 31%, the topic of "Decision Support System" 11% and "System Analysis and Design "10%. The new issues that arose were "Internet of Things", "Machine Learning" and "Artificial Intelligence". Information systems research in Indonesia varies widely, although some studies have a low percentage.
Avaliação do Índice de Anomalia de Chuva para a região central do Estado do Espírito Santo
Authors: Rocha Marcelo Henrique Fernandes de Faria , Oliveira Alisson Souza de , Moreira Gustavo Andrade , Soares Karina de Jesus , Marques Rosângela Francisca de Paula Vitor , Coelho Antonione Araujo 
Published: September 2021

Índices climáticos como o de Anomalia de Chuva (IAC) permitem o desenvolvimento de sistemas de monitoramento de períodos secos ou chuvosos e facilitam a comunicação de informações sobre anomalias climáticas para diversos setores da sociedade. Neste sentido, o objetivo deste trabalho foi avaliar o IAC da região central do Estado do Espírito Santo considerando a metodologia proposta por Rooy (1965) e adaptada por Freitas (2004) e Araújo (2009). O IAC das estações adotadas foi comparado com os parâmetros das Zonas Naturais do Espírito Santo (Espírito Santo, 1999). Adicionalmente, visando verificar os impactos que o clima global causa sobre a distribuição pluviométrica regional, foram consideradas eventuais influências de El Niño (EN) e La Niña (LN) sobre os valores de IAC obtidos. Os resultados indicam alterações nos padrões das chuvas da região, aparentes contradições em relação ao zoneamento natural do Espírito Santo e, por fim e não menos importante, notável variabilidade pluviométrica nos postos avaliados, circunstâncias que revelam ser imperiosa a realização de mais pesquisas climatológicas na região com enfoque na precipitação pluviométrica. O IAC médio da área de estudo aponta para o aumento da ocorrência de eventos severos, constatação particularmente importante tendo em vista as possíveis implicações negativas na cadeia socioeconômica da região bem como os desastres socioambientais potencialmente associados.
Outcomes of Spironolactone Withdrawal in Dilated Cardiomyopathy With Improved Ejection Fraction
Authors: Chen Yanjia , Qiu Zeping , Jiang Jie , Su Xiuxiu , Huang Fanyi , Tang Jing , Jin Wei 
Published: September 2021

Background: The feasibility of spironolactone withdrawal in dilated cardiomyopathy patients with improved ejection fraction remains unknown. This study sought to determine whether spironolactone can be withdrawn safely in this circumstance.Methods: Consecutive patients with idiopathic dilated cardiomyopathy and prescribed spironolactone at discharge were included in this prospective, observational cohort using the Risk Evaluation and Management in Heart Failure Trial (NCT02998788) database. Those patients who experienced an absolute left ventricular ejection fraction (LVEF) improvement ≥10% and a second measurement of LVEF &gt;40% would choose whether to continue spironolactone therapy and be included in final analysis. The primary endpoint was dilated cardiomyopathy relapse within 12 months, defined as a more than 10% reduction in LVEF, a 15% or greater increase in LVESVi, a 2-fold rise in NT-proBNP, or clinical signs of heart failure.Results: Seventy patients achieved an ejection fraction improvement and were included in the final analysis, of whom 30 chose to continue spironolactone and 40 decided to withdraw. In primary endpoint analysis, 23 (58%) patients from the withdrawal group and 4 (13%) patients from the continuation group relapsed (relative risk for relapse: 4.31; 95% CI: 1.67–11.11; p &lt; 0.001). Patients from the withdrawal group experienced more symptom aggravation than the continuation group. No secondary safety endpoint was recorded. Improvements in cardiac structure parameters were no longer observed after spironolactone withdrawal, while improvements persisted in continuation group.Conclusions: Most dilated cardiomyopathy patients with improved ejection fraction will relapse after spironolactone withdrawal. These results should be weighed before spironolactone withdrawal was attempted.
Catecholamine Surges Cause Cardiomyocyte Necroptosis via a RIPK1–RIPK3-Dependent Pathway in Mice
Authors: Wu Penglong , Cai Mingqi , Liu Jinbao , Wang Xuejun 
Published: September 2021

Background: Catecholamine surges and resultant excessive β-adrenergic stimulation occur in a broad spectrum of diseases. Excessive β-adrenergic stimulation causes cardiomyocyte necrosis, but the underlying mechanism remains obscure. Necroptosis, a major form of regulated necrosis mediated by RIPK3-centered pathways, is implicated in heart failure; however, it remains unknown whether excessive β-adrenergic stimulation-induced cardiac injury involves necroptosis. Hence, we conducted the present study to address these critical gaps.Methods and Results: Two consecutive daily injections of isoproterenol (ISO; 85 mg/kg, s.c.) or saline were administered to adult mixed-sex mice. At 24 h after the second ISO injection, cardiac area with Evans blue dye (EBD) uptake and myocardial protein levels of CD45, RIPK1, Ser166-phosphorylated RIPK1, RIPK3, and Ser345-phosphorylated MLKL (p-MLKL) were significantly greater, while Ser321-phosphorylated RIPK1 was significantly lower, in the ISO-treated than in saline-treated wild-type (WT) mice. The ISO-induced increase of EBD uptake was markedly less in RIPK3−/− mice compared with WT mice (p = 0.016). Pretreatment with the RIPK1-selective inhibitor necrostatin-1 diminished ISO-induced increases in RIPK3 and p-MLKL in WT mice and significantly attenuated ISO-induced increases of EBD uptake in WT but not RIPK3−/− mice.Conclusions: A large proportion of cardiomyocyte necrosis induced by excessive β-adrenergic stimulation belongs to necroptosis and is mediated by a RIPK1–RIPK3-dependent pathway, identifying RIPK1 and RIPK3 as potential therapeutic targets for catecholamine surges.