bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lithium-Ion Battery State of Health Estimation Based on Improved Deep Extreme Learning Machine
Authors: Zhang Yu , Zeng Wanwan , Chang Chun , Wang Qiyue , Xu Si 
Published: September 2021

Abstract
Accurate estimation of the state of health (SOH) is an important guarantee for safe and reliable battery operation. In this paper, an online method based on indirect health features (IHFs) and sparrow search algorithm fused with deep extreme learning machine (SSA-DELM) of lithium-ion batteries is proposed to estimate SOH. First, the temperature and voltage curves in the battery discharge data are acquired, and the optimal intervals are obtained by ergodic method. Discharge temperature difference at equal time intervals (DTD-ETI) and discharge time interval with equal voltage difference (DTI-EVD) are extracted as IHF. Then, the input weights and hidden layer thresholds of the DELM algorithm are optimized using SSA, and the SSA-DELM model is applied to the estimation of battery's SOH. Finally, the established model is experimentally validated using the battery data, and the results show that the method has high prediction accuracy, strong algorithmic stability, and good adaptability.
A Comparative Analysis of Flame Temperature, Radiation Behaviors, and NOx Emission of an Oil Burner Fueled With Nano Biodiesel Blend Fuel Containing Suspended Energetic and Non-energetic Metal Nanoparticles
Authors: Pourhoseini S. H. , Ghodrat Maryam 
Published: September 2021

Abstract
This study presents a comparative experimental approach to analyze flame temperature, emissions, and radiation behaviors of an oil furnace fueled with nano biodiesel blend fuel containing suspended energetic and non-energetic nanoparticles (NPs). Iron NPs were used as energetic nanoparticles, and alumina (Al2O3) was selected as non-energetic NPs. A dilute homogeneous mixture (500 ppm) was provided from each NPs in B20 blend fuel. The fuels were burned in an oil burner subsequently, and infrared radiation (IR) images of flame, profiles of flame temperature, luminous and total radiation and NOx and CO emissions were gauged and compared. Measurements showed that both NPs improve the evaporation rate of fuel droplets and displace the peak of flame temperature to the flame upstream region. Moreover, nano biodiesel blend fuel containing energetic iron NPs elevates flame temperature while the non-energetic alumina NPs reduce the peak of flame temperature. In addition, both NPs strengthen the nucleation and growth of intermediate soot particles. These fuels containing suspended particles also lead to an increase in the intermediate soot particles content of flame and flame emissivity. This increases IR, luminous, and total flame radiation. The improvement of average flame radiative flux for nano biodiesel blend fuel containing energetic iron NPs and non-energetic alumina NPs is as high as 25% and 10%, respectively. Also, using energetic iron NPs and non-energetic alumina NPs in B20 fuel reduces the NOx emission by 13% and 11%, respectively.
New Records of Rare Psychrolutid Fishes (Psychrolutidae) in the Sea of Okhotsk
Authors: Saveliev P. A. 
Published: September 2021

Abstract
Two rare species of psychrolutid fish (Psychrolutidae) were found in the Sea of Okhotsk. Psychrolutes dolganovi was found at a depth of 142 m near Urup Island (southern Kuril Islands); earlier the species was known only from the holotype collected off the Pacific coast of Iturup Island. This species is recorded in the Sea of Okhotsk for the first time. P. pustulosus was collected at depths of 205–400 m along central part of Kuril Islands and in the northwestern part of the Sea of Okhotsk at depths of 240–294 m. A key to the species of the genus Psychrolutes inhabiting the northern Pacific Ocean is presented.
Use of metformin to prolong gestation in preterm pre-eclampsia: randomised, double blind, placebo controlled trial
Authors: Cluver Catherine A , Hiscock Richard , Decloedt Eric H , Hall David R , Schell Sonja , Mol Ben W , Brownfoot Fiona , Kaitu’u-Lino Tu’uhevaha J , Walker Susan P , Tong Stephen 
Published: September 2021

Abstract

Objective
To evaluate whether extended release metformin could be used to prolong gestation in women being expectantly managed for preterm pre-eclampsia.

Design
Randomised, double blind, placebo controlled trial.

Setting
Referral hospital in Cape Town, South Africa.

Participants
180 women with preterm pre-eclampsia between 26+0 to 31+6 weeks’ gestation undergoing expectant management: 90 were randomised to extended release metformin and 90 to placebo.

Intervention
3 g of oral extended release metformin or placebo daily, in divided doses, until delivery.

Main outcome measure
The primary outcome was prolongation of gestation.

Results
Of 180 participants, one woman delivered before taking any trial drug. The median time from randomisation to delivery was 17.7 days (interquartile range 5.4-29.4 days; n=89) in the metformin arm and 10.1 (3.7-24.1; n=90) days in the placebo arm, a median difference of 7.6 days (geometric mean ratio 1.39, 95% confidence interval 0.99 to 1.95; P=0.057). Among those who continued to take the trial drug at any dose, the median prolongation of gestation in the metformin arm was 17.5 (interquartile range 5.4-28.7; n=76) days compared with 7.9 (3.0-22.2; n=74) days in the placebo arm, a median difference of 9.6 days (geometric mean ratio 1.67, 95% confidence interval 1.16 to 2.42). Among those who took the full dosage, the median prolongation of gestation in the metformin arm was 16.3 (interquartile range 4.8-28.8; n=40) days compared with 4.8 (2.5-15.4; n=61) days in the placebo arm, a median difference of 11.5 days (geometric mean ratio 1.85, 95% confidence interval 1.14 to 2.88). Composite maternal, fetal, and neonatal outcomes and circulating concentrations of soluble fms-like tyrosine kinase-1, placental growth factor, and soluble endoglin did not differ. In the metformin arm, birth weight increased non-significantly and length of stay decreased in the neonatal nursery. No serious adverse events related to trial drugs were observed, although diarrhoea was more common in the metformin arm.

Conclusions
This trial suggests that extended release metformin can prolong gestation in women with preterm pre-eclampsia, although further trials are needed. It provides proof of concept that treatment of preterm pre-eclampsia is possible.

Trial registration

Pan African Clinical Trial Registry PACTR201608001752102
https://pactr.samrc.ac.za/
.
Risk factors of infant mortality in rural The Gambia: a retrospective cohort study
Authors: Jarde Alexander , Mohammed Nuredin Ibrahim , Gomez Pierre , Saine Pa Cheboh , D'Alessandro Umberto , Roca Anna 
Published: September 2021

ObjectiveThe main objective was to assess the risk factors for infant mortality among children living in the Health and Demographic Surveillance System (HDSS) in Farafenni, The Gambia. Our secondary objective was to assess these risks separately in the neonatal and postneonatal (>28 days) period.DesignRetrospective cohort study.SettingHDSS in an urban centre and surrounding area in The Gambia.Patients7365 infants (47% female) born between 2014 and 2018, of which 126 (1.71%) died in the first year.Main outcome measuresInfant mortality.ResultsRisk factors for mortality were death of any sibling (HR 2.78, 95% CI 1.54 to 5.00), having a twin (HR 1.96, 95% CI 1.01 to 3.80), being born in the harvest season (HR 1.55, 95% CI 1.07 to 2.24), living in a rural village (HR 4.34, 95% CI 2.03 to 9.29) and longer distance to the nearest village with a public health centre (HR 1.33, 95% CI 1.11 to 1.59). In addition, no breast feeding (HR 10.73, 95% CI 6.83 to 16.86) and no BCG vaccination in the first week of life (HR 3.47, 95% CI 1.07 to 11.24) were associated with infant mortality. Similar risk factors were found in the neonatal and postneonatal periods.ConclusionMost risk factors associated with infant mortality (neonatal and postneonatal) are not easily modifiable at the individual level and would require programmatic approaches to target vulnerable infants and facilitate access to health services.
Exclusive production of $$\rho $$-mesons in high-energy factorization at HERA and EIC
Authors: Bolognino A. D. , Celiberto F. G. , Ivanov D. Yu. , Papa A. , Schäfer W. , Szczurek A. 
Published: September 2021

AbstractWe study cross sections for the exclusive diffractive leptoproduction of $$\rho $$
ρ
-mesons, $$\gamma ^*~p~\rightarrow ~\rho ~p$$

γ
∗

p

→

ρ

p

, within the framework of high-energy factorization. Cross sections for longitudinally and transversally polarized mesons are shown. We employ a wide variety of unintegrated gluon distributions available in the literature and compare to HERA data. The resulting cross sections strongly depend on the choice of unintegrated gluon distribution. We also present predictions for the proton target in the kinematics of the Brookhaven EIC.
Associations Between Inflammation, Cardiovascular Regenerative Capacity, and Cardiovascular Events: A Cohort Study
Authors: Almuwaqqat Zakaria , Hwan Kim Jeong , Garcia Mariana , Ko Yi-An , Moazzami Kasra , Lima Bruno , Sullivan Samaah , Alkhalaf Jamil , Mehta Anurag , Shah Amit J. , Hussain Mohammad S. , Pearce Brad D. , Bremner J. Douglas , Waller Edmund K. , Vaccarino Viola , Quyyumi Arshed A. 
Published: September 2021

Objective:
Circulating progenitor cells possess immune modulatory properties and might mitigate inflammation that is characteristic of patients with coronary artery disease. We hypothesized that patients with fewer circulating progenitor cells (CPCs) will have higher inflammatory markers and worse outcomes.

Approach and Results:

Patients with stable coronary artery disease were enrolled in a prospective study enumerating CPCs as CD (cluster of differentiation)-34–expressing mononuclear cells (CD34+) and inflammation as levels of IL (interleukin)-6 and high-sensitivity CRP (C-reactive protein) levels. Patients were followed for 5 years for the end points of death and myocardial infarction with repeat inflammatory biomarkers measured after a median of 2 years. In the entire cohort of 392 patients, IL-6 and high-sensitivity CRP levels remained unchanged (0.3±2.4 pg/mL and 0.1±1.0 mg/L;
P
=0.45) after 2 years. CPC counts (log-transformed) were inversely correlated with the change in IL-6 levels (r, −0.17;
P
<0.001). Using linear regression, IL-6 and high-sensitivity CRP levels declined by −0.59 (95% CI, −0.90 to −0.20) pg/mL and −0.13 (−0.28 to 0.01) mg/L per 1 log higher CPC counts after adjustment for the demographic and clinical variables, as well as medications. Using Cox models adjusted for these risk factors, a rise in 1 pg/mL of IL-6 was associated with a 11% (95% CI, 9–13) greater risk of death/myocardial infarction. We found that the change in IL6 level partly (by 40%) mediated the higher risk of adverse events among those with low CPC counts.

Conclusions:
Reduced cardiovascular regenerative capacity is independently associated with progressive inflammation in patients with coronary artery disease that in turn is associated with poor outcomes.

Graphic Abstract:
A graphic abstract is available for this article.
Receptor and Molecular Mechanism of AGGF1 Signaling in Endothelial Cell Functions and Angiogenesis
Authors: Wang Jingjing , Peng Huixin , Timur Ayse Anil , Pasupuleti Vinay , Yao Yufeng , Zhang Teng , You Sun-Ah , Fan Chun , Yu Yubing , Jia Xinzhen , Chen Jing , Xu Chengqi , Chen Qiuyun , Wang Qing 
Published: September 2021

Objective:Angiogenic factor AGGF1 (angiogenic factor and G-patch and FHA [Forkhead-associated] domain 1) promotes angiogenesis as potently as VEGFA (vascular endothelial growth factor A) and regulates endothelial cell (EC) proliferation, migration, specification of multipotent hemangioblasts and venous ECs, hematopoiesis, and vascular development and causes vascular disease Klippel-Trenaunay syndrome when mutated. However, the receptor for AGGF1 and the underlying molecular mechanisms remain to be defined.Approach and Results:Using functional blocking studies with neutralizing antibodies, we identified α5β1 as the receptor for AGGF1 on ECs. AGGF1 interacts with α5β1 and activates FAK (focal adhesion kinase), Src, and AKT. Functional analysis of 12 serial N-terminal deletions and 13 C-terminal deletions by every 50 amino acids mapped the angiogenic domain of AGGF1 to a domain between amino acids 604-613 (FQRDDAPAS). The angiogenic domain is required for EC adhesion and migration, capillary tube formation, and AKT activation. The deletion of the angiogenic domain eliminated the effects of AGGF1 on therapeutic angiogenesis and increased blood flow in a mouse model for peripheral artery disease. A 40-mer or 15-mer peptide containing the angiogenic domain blocks AGGF1 function, however, a 15-mer peptide containing a single amino acid mutation from −RDD- to −RGD- (a classical RGD integrin-binding motif) failed to block AGGF1 function.Conclusions:We have identified integrin α5β1 as an EC receptor for AGGF1 and a novel AGGF1-mediated signaling pathway of α5β1-FAK-Src-AKT for angiogenesis. Our results identify an FQRDDAPAS angiogenic domain of AGGF1 crucial for its interaction with α5β1 and signaling.
Slit-band gastropods (Pleurotomariida) from the Upper Triassic St. Cassian Formation and their diversity dynamics in the Triassic
Authors: KARAPUNAR BARAN , NÜTZEL ALEXANDER 
Published: September 2021

The St. Cassian Formation, Italy, has yielded the most diverse marine invertebrate fauna known from the Triassic. A quarter of all described Triassic gastropod species has been reported from this formation. Most of the gastropod species from the St. Cassian Formation were erected in the 19th century and many of them are known only from their original figures and descriptions. The failure to study type specimens resulted in many erroneous identifications by subsequent authors. Here, we revise the slit band gastropods (Pleurotomariida) from the St. Cassian Formation—one of the major groups present in this formation. A total of 77 nominate Pleurotomariida species belonging to 29 genera and 11 families are present in the St. Cassian Formation which comprises approximately 14 % of the total nominate gastropod species of that formation. In addition, we revise several taxa that had been wrongly assigned to Pleurotomariida. As other gastropod clades, Pleurotomariida experienced a major extinction at the end-Permian mass extinction event. As in the Late Palaeozoic, their relative abundance in gastropod faunas continued to be 30 % in some Anisian faunas but decreased to 5–10 % afterwards. Their diversification at generic level became interrupted by an extinction event within the Carnian, probably by the Carnian Pluvial Event. As a result of their sluggish recovery compared to the other gastropod groups, their species diversity decreased from 26 % during the Permian to 18 % during the Triassic.
Type specimens of the following genera are studied: Proteomphalus, Rhaphistomella, Temnotropis, Kittlidiscus, Stuorella, Schizogonium, Wortheniella, Bandelium, Lancedellia, Rinaldoella, Pseudowortheniella, Paleunema, Ampezzalina, Bandelastraea, Cheilotomona, Pseudoscalites, Delphinulopsis, and Cochlearia.
Nine new pleurotomariidan genera are erected: Amplitomaria, Pseudoananias, Lineacingulum, Pressulasphaera, Cancellotomaria, Acutitomaria, Lineaetomaria, Nodocingulum, and Striacingulum.
Eight new species are described: Schizogonium undae, Acutitomaria kustatscherae, Wortheniella klipsteini, Wortheniella paolofedelei, Rinaldoella tornata, Nodocingulum ernstkittli, Nodocingulum? turris, and Laubella subsulcata.
Eoworthenia frydai is a new replacement name for Worthenia rarissima Barrande.
Interannual and decadal variability of Arctic summer sea ice associated with atmospheric teleconnection patterns during 1850-2017
Authors: Cai Qiongqiong , Beletsky Dmitry , Wang Jia , Lei Ruibo 
Published: September 2021

AbstractThe interannual and decadal variability of summer Arctic sea ice is analyzed, using the longest reconstruction (1850-2017) of Arctic sea ice extent available, and its relationship with the dominant internal variabilities of the climate system is further investigated quantitatively. The leading empirical orthogonal function (EOF) mode of summer Arctic sea ice variability captures an in-phase fluctuation over the Arctic Basin. The second mode characterizes a sea ice dipolar pattern with out-of-phase variability between the Pacific Arctic and the Atlantic Arctic. Summer sea ice variability is impacted by the major internal climate patterns: the Atlantic Multidecadal Oscillation (AMO), North Atlantic Oscillation (NAO), Arctic Oscillation (AO), Pacific Decadal Oscillation (PDO) and Dipole Anomaly (DA), with descending order of importance based on the multiple regression analyses. The internal climate variability of the five teleconnection patterns accounts for up to 46% of the total variance in sea ice mode 1 (thermodynamical effect), and up to 30% of the total variance in mode 2 (dynamical effect). Furthermore, the variability of sea ice mode 1 decreased from 46% during 1953-2017 to 28% during 1979-2017, while the variability of mode 2 increased from 11% during 1953-2017 to 30% during 1979-2017. The increasingly greater reduction of Arctic summer sea ice during the recent four decades was enhanced with the positive ice/ocean albedo feedback loop being accelerated by the Arctic amplification, contributed in part by the atmospheric thermodynamical forcing from -AO, +NAO, +DA, +AMO, and –PDO and by the dynamical transpolar sea ice advection and outflow driven by +DA- and +AMO-derived strong anomalous meridional winds. Further analysis, using multiple large ensembles of climate simulations and single-forcing ensembles, indicates that the mode 1 of summer sea ice, dominated by the multidecadal oscillation, is partially a forced response to anthropogenic warming.
Effect of Operating Room Personnel Generation on Perceptions and Responses to Surgeon Behavior
Authors: Luc Jessica G. Y. , Corsini Erin M. , Mitchell Kyle G. , Correa Arlene M. , Turner Nadine S. , Vaporciyan Ara A. , Antonoff Mara B. 
Published: September 2021

Background Little is known regarding the impact of operating room (OR) personnel generation on their perceptions to various surgeon behaviors. We aimed to characterize these relationships by evaluating their responses to 5 realistic intraoperative scenarios. Methods Operating room personnel were asked to assess surgeon OR behavior across a standardized set of 5 scenarios via an online survey. For each scenario, respondents were asked to identify the behavior as either acceptable, unacceptable but would ignore, unacceptable and would confront the surgeon, or unacceptable and would report to management. Chi-squared analyses were used to compare responses to surgeon behavior with respondent generation. Results There were 3101 respondents, of which 41% of respondents were baby boomers (n = 1280), 31% were generation (Gen) X (n = 955), and 28% were Gen Y (n = 866). Overall, when compared to Gen X or Gen Y, baby boomers were significantly more likely to find surgeon behaviors of impatience ( P < .001), being late for a case ( P < .001), swearing in the OR ( P < .001), and shouting with a bleeding patient ( P = .001) to be inappropriate and would talk to the surgeon. Alternatively, Gen Y respondents were more likely to find fault with surgeon behaviors that deviate from rules and regulations, such as forgetting a time-out ( P = .001), when compared to baby boomers and Gen X respondents. Discussion Results of our study demonstrate that OR personnel generation affects their perceptions and response to surgeon behavior. Understanding these tendencies can guide efforts to improve OR interactions among team members.
An Overview of Amish Mortalities at a Level I Trauma Center
Authors: Morgan Madison E. , Brown Catherine Ting , Whitney Larissa , Bonneville Kelly , Perea Lindsey L. 
Published: September 2021

Background The Amish population is a unique subset of patients that may require a specialized approach due to their lifestyle differences compared to the general population. With this reasoning, Amish mortalities may differ from typical trauma mortality patterns. We sought to provide an overview of Amish mortalities and hypothesized that there would be differences in injury patterns between mortalities and survivors. Methods All Amish trauma patients who presented and were captured by the trauma registry at our Level I trauma center over 20 years (1/2000-2004/2020) were analyzed. A retrospective chart review was subsequently performed. Patients who died were of interest to this study. Demographic and clinical variables were analyzed for the mortalities. Mortalities were then compared to Amish patients who survived. Results There were 1827 Amish trauma patients during the study period and, of these, 32 (1.75%) were mortalities. The top 3 mechanisms of injury leading to mortality were falls (34.4%), pedestrian struck (21.9%), and farming accidents (15.6%). Pediatric (age ≤ 14y) (25%) and geriatric (age ≥ 65y) (28.1%) had the highest percentage of mortalities. Mortalities in the Amish population were significantly older (mean age: 39 years vs 27 years, P = .003) and had significantly higher ISS (mean ISS: 29 vs 10, P < .001) compared to Amish patients who survived. Discussion The majority of mortalities occurred in the pediatric and geriatric age groups and were falls. Further intervention and outreach in the Amish population should be done to highlight this particular cause of mortality. Level of Evidence Level III, epidemiological.
Impact of a Body Mass Index Threshold on Abdominal Wall Hernia Repair at a Safety-Net Hospital
Authors: James Tayler J , Hawley Lauren , Ding Li , Alicuben Evan T , Samakar Kamran 
Published: September 2021

Background Body mass index (BMI) thresholds are utilized as a preoperative optimization strategy for obese patients prior to elective abdominal wall hernia repair. The objectives of this study were to determine the proportion of patients at our institution who ultimately underwent hernia repair after initial deferral due to BMI and to evaluate outcomes of those who required emergent repair during the deferral period. Methods A retrospective review was performed from 2016 to 2018 to identify all patients with abdominal wall hernias who were deferred surgery due to BMI. Patient characteristics, hernia type, change in BMI, progression to surgery, acuity of surgery (elective or emergent), and postoperative outcomes were examined. Results 200 patients were deferred hernia repair due to BMI. Of these, 150 (75%) did not undergo repair over a mean period of 27 months. The remaining 50 patients ultimately underwent repair, 36 of which (72%) were elective and 14 (28%) emergent. The mean initial BMI of the elective group was 35.3 ± 1.8, compared to 39.1 ± 5.3 in the no surgery group and 40.6 ± 8.2 in the emergent group ( P < .01). While the elective group lost weight before surgery, the other groups did not. Patients who required emergent surgery had worse outcomes than those repaired electively. Conclusions Preoperative weight loss is unsuccessful in most obese patients presenting for abdominal wall hernia repair at our institution. Patients who required emergent hernia repair had worse outcomes than those who underwent elective repair. Our institution’s BMI threshold is a failed optimization strategy that needs to be reconsidered.