bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Prescribed Fire on Northern Bobwhite Nesting Ecology
Authors: Rosche Sarah B. , Moorman Christopher E. , Kroeger Anthony J. , Pacifici Krishna , Jones Jeffrey G. , Deperno Christopher S. 
Published: June 2021

ABSTRACTRepeated prescribed fire can create and maintain areas with sparse overstory tree cover and a dense grass‐forb‐shrub understory, providing habitat for northern bobwhite (Colinus virginianus; hereafter, bobwhite). Despite potential benefits of prescribed fires for conserving bobwhite habitat, burning during the nesting season may destroy bobwhite nests and reduce available nesting cover. We monitored radio‐transmittered bobwhite (n = 104) from 2016 to 2018 to describe nest‐site selection and determine the risk of nest destruction on a 17,000‐ha North Carolina military installation, Fort Bragg, managed with rotational growing‐season and dormant‐season prescribed fires on an approximate 3‐year return interval. We located 48 nests, of which 8 (16%) were in areas burned the same year, 9 (19%) were in one‐year post fire, 25 (52%) were in 2‐years post fire, and 6 (13%) were in ≥3‐years post fire areas. We compared vegetation composition and structure at nests to nearby random locations and determined bobwhite selected nest sites with greater woody understory and wiregrass cover, lower basal areas of pines and hardwoods, and less distance to the nearest road. Two nests (6.7%) were destroyed during prescribed fires, but success of incubated nests was high (67%). We calculated the overall risk of nest destruction by prescribed fire as the proportion of active nests in areas with ≥3 years since last fire multiplied by the proportion of the study area burned each week. Overall, 11% (weekly  = 0.75%, range = 0–3%) of the study area was burned during the 2016 nesting season (3 June to 3 September), 4% (weekly  = 0.31%, range 0–2%) of the study area was burned during the 2017 nesting season (5 June to 2 September), and 7.5% (weekly  = 0.58%, range 0–5%) of the study area was burned during the 2018 nesting season (3 June to 31 August). We estimated that no more than 0.75% of bobwhite nests across the study site were exposed to fire annually. Most growing‐season fires occurred before the bobwhite nesting season, which limited direct effects of prescribed fire on bobwhite nest survival. However, shifting prescribed fires to later in the growing season to better match the historical lightning season (i.e., after 1 June) would increase the risk of nest destruction. Because bobwhite used older roughs (i.e. areas 2 years since fire) for nesting, shortening the fire return interval to less than 3 years would increase the proportion of nests exposed to fire. Additionally, a shortened fire return interval would decrease available nesting cover, especially in regions with low soil fertility where vegetation change following fire is less rapid than on more productive soils. © 2021 The Wildlife Society.
Compatibility of state constraints and dynamics for multiagent control systems
Authors: Cavagnari Giulia , Marigonda Antonio , Quincampoix Marc 
Published: June 2021

AbstractThis study concerns the problem of compatibility of state constraints with a multiagent control system. Such a system deals with a number of agents so large that only a statistical description is available. For this reason, the state variable is described by a probability measure on $${\mathbb {R}}^d$$

R

d

representing the density of the agents and evolving according to the so-called continuity equation which is an equation stated in the Wasserstein space of probability measures. The aim of the paper is to provide a necessary and sufficient condition for a given constraint (a closed subset of the Wasserstein space) to be compatible with the controlled continuity equation. This new condition is characterized in a viscosity sense as follows: the distance function to the constraint set is a viscosity supersolution of a suitable Hamilton–Jacobi–Bellman equation stated on the Wasserstein space. As a byproduct and key ingredient of our approach, we obtain a new comparison theorem for evolutionary Hamilton–Jacobi equations in the Wasserstein space.
Adenosine-induced Asystole during AVM Embolization
Authors: Hellstern V. , Bhogal P. , Aguilar Pérez M. , Alfter M. , Kemmling A. , Henkes E. , Ganslandt O. , Henkes H. 
Published: June 2021

Abstract
Background
Adenosine induced cardiac standstill has been used intraoperatively for both aneurysm and arteriovenous malformation (AVM) surgery and embolization. We sought to report the results of adenosine induced cardiac standstill as an adjunct to endovascular embolization of brain AVMs.

Material and Methods
We retrospectively identified patients in our prospectively maintained database to identify all patients since January 2007 in whom adenosine was used to induce cardiac standstill during the embolization of a brain AVM. We recorded demographic data, clinical presentation, Spetzler Martin grade, rupture status, therapeutic intervention and number of embolization sessions, angiographic and clinical results, clinical and radiological outcomes and follow-up information.

Results
We identified 47 patients (22 female, 47%) with average age 42 ± 17 years (range 6–77 years) who had undergone AVM embolization procedures using adjunctive circulatory standstill with adenosine. In total there were 4 Spetzler Martin grade 1 (9%), 9 grade 2 (18%), 15 grade 3 (32%), 8 grade 4 (18%), and 11 grade 5 (23%) lesions. Of the AVMs six were ruptured or had previously ruptured. The average number of embolization procedures per patient was 5.7 ± 7.6 (range 1–37) with an average of 2.6 ± 2.2 (range 1–14) embolization procedures using adenosine. Overall morbidity was 17% (n = 8/47) and mortality 2.1% (n = 1/47), with permanent morbidity seen in 10.6% (n = 5/47) postembolization. Angiographic follow-up was available for 32 patients with no residual shunt seen in 26 (81%) and residual shunts seen in 6 patients (19%). The angiographic follow-up is still pending in 14 patients. At last follow-up 93.5% of patients were mRS ≤2 (n = 43/46).

Conclusion
Adenosine induced cardiac standstill represents a viable treatment strategy in high flow AVMs or AV shunts that carries a low risk of mortality and permanent neurological deficits.
Technical standardization of ICG near-infrared fluorescence (NIRF) laparoscopic partial nephrectomy for duplex kidney in pediatric patients
Authors: Esposito Ciro , Autorino Giuseppe , Coppola Vincenzo , Esposito Giorgia , Paternoster Mariano , Castagnetti Marco , Cardone Roberto , Cerulo Mariapina , Borgogni Rachele , Cortese Giuseppe , Escolino Maria 
Published: June 2021

Abstract
Purpose
This study aimed to standardize the operative technique of indocyanine green (ICG) near-infrared fluorescence (NIRF) laparoscopic partial nephrectomy (LPN) and compare it with the standard technique.

Methods
In the last 4 years, we performed 22 LPN (14 right-sided, 8 left-sided) in children with non-functioning moiety of duplex kidney. Patients included 12 girls and 10 boys with a median age of 3.9 years (range 1–10). Patients were grouped according to the use of ICG-NIRF: G1 included 12 patients operated using ICG-NIRF and G2 included 10 patients receiving the standard technique. We standardized the technique of injection of ICG in three different steps.

Results
The median operative time was significantly lower in G1 [87 min (range 68–110)] compared with G2 [140 min (range 70–220)] (p = 0.001). One intra-operative complication occurred in G2. At post-operative ultrasound (US), the residual moiety was normal in all patients. An asymptomatic renal cyst related to the site of surgery was visualized at US in 8/22 (36%), with a significantly higher incidence in G2 (6/10, 60%) compared with G1 (2/12, 16.6%) (p = 0.001). Renogram demonstrated no loss of function of residual moiety. No allergic reactions to ICG occurred.

Conclusion
ICG-NIRF LPN is technically easier, quicker, and safer compared with the standard technique. The main advantages of using ICG-NIRF during LPN are the clear identification of normal ureter, vasculature of non-functioning pole, and demarcation line between the avascular and the perfused pole. The main limitation of ICG technology remains the need for specific laparoscopic equipment that is not always available.
Single-cell biology to decode the immune cellular composition of kidney inflammation
Authors: Zhao Yu , Panzer Ulf , Bonn Stefan , Krebs Christian F. 
Published: June 2021

AbstractSingle-cell biology is transforming the ability of researchers to understand cellular signaling and identity across medical and biological disciplines. Especially for immune-mediated diseases, a single-cell look at immune cell subtypes, signaling, and activity might yield fundamental insights into the disease etiology, mechanisms, and potential therapeutic interventions. In this review, we highlight recent advances in the field of single-cell RNA profiling and their application to understand renal function in health and disease. With a focus on the immune system, in particular on T cells, we propose some key directions of understanding renal inflammation using single-cell approaches. We detail the benefits and shortcomings of the various technological approaches outlined and give advice on potential pitfalls and challenges in experimental setup and computational analysis. Finally, we conclude with a brief outlook into a promising future for single-cell technologies to elucidate kidney function.
Data dependencies for query optimization: a survey
Authors: Kossmann Jan , Papenbrock Thorsten , Naumann Felix 
Published: June 2021

AbstractEffective query optimization is a core feature of any database management system. While most query optimization techniques make use of simple metadata, such as cardinalities and other basic statistics, other optimization techniques are based on more advanced metadata including data dependencies, such as functional, uniqueness, order, or inclusion dependencies. This survey provides an overview, intuitive descriptions, and classifications of query optimization and execution strategies that are enabled by data dependencies. We consider the most popular types of data dependencies and focus on optimization strategies that target the optimization of relational database queries. The survey supports database vendors to identify optimization opportunities as well as DBMS researchers to find related work and open research questions.
Health state utility values by cancer stage: a systematic literature review
Authors: Pourrahmat Mir-Masoud , Kim Ashley , Kansal Anuraag R. , Hux Marg , Pushkarna Divya , Fazeli Mir Sohail , Chung Karen C. 
Published: June 2021

Abstract
Objectives
Cancer diagnoses at later stages are associated with a decrease in health-related quality of life (HRQOL). Health state utility values (HSUVs) reflect preference-based HRQOL and can vary based on cancer type, stage, treatment, and disease progression. Detecting and treating cancer at earlier stages may lead to improved HRQOL, which is important for value assessments. We describe published HSUVs by cancer type and stage.

Methods
A systematic review was conducted using Embase, MEDLINE®, EconLit, and gray literature to identify studies published from January 1999 to September 2019 that reported HSUVs by cancer type and stage. Disutility values were calculated from differences in reported HSUVs across cancer stages.

Results
From 13,872 publications, 27 were eligible for evidence synthesis. The most frequent cancer types were breast (n = 9), lung (n = 5), colorectal (n = 4), and cervical cancer (n = 3). Mean HSUVs decreased with increased cancer stage, with consistently lower values seen in stage IV or later-stage cancer across studies (e.g., − 0.74, − 0.44, and − 0.51 for breast, colorectal, and cervical cancer, respectively). Disutility values were highest between later-stage (metastatic or stage IV) cancers compared to earlier-stage (localized or stage I–III) cancers.

Conclusions
This study provides a summary of HSUVs across different cancer types and stages that can inform economic evaluations. Despite the large variation in HSUVs overall, a consistent decline in HSUVs can be seen in the later stages, including stage IV. These findings indicate substantial impairment on individuals’ quality of life and suggest value in early detection and intervention.
Depositional setting and limiting factors of early Late Cretaceous glaucony formation: implications from Cenomanian glauconitic strata (Elbtal Group, Germany)
Authors: Wilmsen Markus , Bansal Udita 
Published: June 2021

AbstractCenomanian strata of the Elbtal Group (Saxony, eastern Germany) reflect a major global sea-level rise and contain, in certain intervals, a green authigenic clay mineral in abundance. Based on the integrated study of five new core sections, the environmental background and spatio-temporal patterns of these glauconitic strata are reconstructed and some general preconditions allegedly needed for glaucony formation are critically questioned. XRD analyses of green grains extracted from selected samples confirm their glauconitic mineralogy. Based on field observations as well as on the careful evaluation of litho- and microfacies, 12 glauconitc facies types (GFTs), broadly reflecting a proximal–distal gradient, have been identified, containing granular and matrix glaucony of exclusively intrasequential origin. When observed in stratigraphic succession, GFT-1 to GFT-12 commonly occur superimposed in transgressive cycles starting with the glauconitic basal conglomerates, followed up-section by glauconitic sandstones, sandy glauconitites, fine-grained, bioturbated, argillaceous and/or marly glauconitic sandstones; glauconitic argillaceous marls, glauconitic marlstones, and glauconitic calcareous nodules continue the retrogradational fining-upward trend. The vertical facies succession with upwards decreasing glaucony content demonstrates that the center of production and deposition of glaucony in the Cenomanian of Saxony was the nearshore zone. This time-transgressive glaucony depocenter tracks the regional onlap patterns of the Elbtal Group, shifting southeastwards during the Cenomanian 2nd-order sea-level rise. The substantial development of glaucony in the thick (60 m) uppermost Cenomanian Pennrich Formation, reflecting a tidal, shallow-marine, nearshore siliciclastic depositional system and temporally corresponding to only ~ 400 kyr, shows that glaucony formation occurred under wet, warm-temperate conditions, high accumulation rates and on rather short-term time scales. Our new integrated data thus indicate that environmental factors such as great water depth, cool temperatures, long time scales, and sediment starvation had no impact on early Late Cretaceous glaucony formation in Saxony, suggesting that the determining factors of ancient glaucony may be fundamentally different from recent conditions and revealing certain limitations of the uniformitarian approach.
Bracken fern (Pteridium aquilinum (L.) Kuhn) overgrowth on dry Alpine grassland impedes Red List Orthoptera but supports local orthopteran beta diversity
Authors: Schlegel Jürg , Riesen Matthias 
Published: June 2021

AbstractThe native bracken fern (Pteridium aquilinum(L.) Kuhn) has become increasingly invasive in abandoned or undergrazed Alpine grasslands. Bracken stands are generally assumed to be poor in species, but there is still very little information about the impact on the fauna. We recorded Orthoptera communities of 24 sample plots with varying bracken cover. Compared to plots with only sparse or medium bracken cover, species richness was highly significantly lower in densely overgrown plots, while the former two did not differ markedly. Multivariate ordination analyses revealed gradients with unequal orthopteran communities, showing distinct patterns of bracken cover clustering. Based on indicator values, 13 of 23 Orthoptera species turned out to be significantly or marginally significantly associated with a single bracken cover stratum or a combination of two strata, whereby all nine Red List species were primarily restricted to sparse or medium bracken cover. However, some generalist species were found to favor denser bracken stands, such asTettigonia viridissima, contributing to the local Orthoptera beta diversity. Our data suggest that ongoing rotational sheep grazing with temporary paddocks is regarded as the most preferable management system. However, selected parts of the study area, which have only sparse vegetation and no pressure of bracken or scrub overgrowth, are recommended to be alternately left ungrazed for a few years to allow for the coexistence of different successional stages. Low-intensity bracken control measures, situationally by mowing or uprooting, are considered appropriate and should be pursued.Implications for insect conservationEven though most specialized and rare Orthoptera species in Western Europe tend to prefer sparsely vegetated areas, subareas with medium to even dense vegetation cover might promote certain generalist species, leading to a higher local species richness.
A single institution retrospective analysis on survival based on treatment paradigms for patients with anaplastic oligodendroglioma
Authors: Bush Nancy Ann Oberheim , Young Jacob S. , Zhang Yalan , Dalle Ore Cecilia L. , Molinaro Annette M. , Taylor Jennie , Clarke Jennifer , Prados Michael , Braunstein Steve E. , Raleigh David R. , Chang Susan M. , Berger Mitchel S. , Butowski Nicholas A. 
Published: June 2021

Abstract
Introduction
Anaplastic oligodendrogliomas are high-grade gliomas defined molecularly by 1p19q co-deletion. There is no curative therapy, and standard of care includes surgical resection followed by radiation and chemotherapy. However, the benefit of up-front radiation with chemotherapy compared to chemotherapy alone has not been demonstrated in a randomized control trial. Given the potential long-term consequences of radiation therapy, such as cognitive impairment, arteriopathy, endocrinopathy, and hearing/visual impairment, there is an effort to balance longevity with radiation toxicity.

Methods
We performed a retrospective single institution analysis of survival of patients with anaplastic oligodendroglioma over 20 years.

Results
159 patients were identified as diagnosed with an anaplastic oligodendroglioma between 1996 and 2016. Of those, 40 patients were found to have AO at original diagnosis and had documented 1p19q co-deletion with a median of 7.1 years of follow-up (range: 0.6–16.7 years). After surgery, 45 % of patients were treated with radiation and chemotherapy at diagnosis, and 50 % were treated with adjuvant chemotherapy alone. The group treated with chemotherapy alone had a trend of receiving more cycles of chemotherapy than patients treated with radiation and chemotherapy upfront (p = 0.051). Median overall survival has not yet been reached. The related risk of progression in the upfront, adjuvant chemotherapy only group was almost 5-fold higher than the patients who received radiation and chemotherapy (hazard ratio = 4.85 (1.74–13.49), p = 0.002). However, there was no significant difference in overall survival in patients treated with upfront chemotherapy compared to patients treated upfront with chemotherapy and radiation (p = 0.8). Univariate analysis of age, KPS, extent of resection, or upfront versus delayed radiation was not associated with improved survival.

Conclusions
Initial treatment with adjuvant chemotherapy alone, rather than radiation and chemotherapy, may be an option for some patients with anaplastic oligodendroglioma, as it is associated with similar overall survival despite shorter progression free survival.
Modern Pollen-vegetation Relationships along the Vegetation Gradient in the Bhagirathi Valley, Western Himalaya, India
Authors: Roy Ipsita , Ranhotra Parminder S. , Shekhar Mayank , Bhattacharyya A. , Ghosh Ruby , Sharma Y. K. 
Published: June 2021

Abstract
This study highlights the modern pollen-vegetation relationships along an altitudinal gradient covering the lower temperate (~2,000 masl) to alpine vegetation zones (~3,800 masl) in the Bhagirathi valley, western Himalaya. The pollen dispersal dataset compared with the altitudinal vegetation distribution in the valley shows incoherency between the arboreal taxa and their respective pollen proportions. Discriminant analysis (DA) revealed the role of diurnal valley winds in pollen mixing between altitudinal vegetation zones. Pollen of arboreal taxa are transported profusely from the lower temperate vegetation zones to alpine zone. Whereas pollen of non-arboreal taxa, dominantly growing in the sub-alpine and alpine meadows, remain close to their source and represent the prevailing localized environmental conditions in the valley. Study revealed Pinus and Quercus as dominant arboreal pollen taxa throughout the altitudinal transect with a distinct transition in their representation between ~2,500 and 2,600 masl. High percentage of Pinus (Quercus) pollen below (above) this transition zone nearly corresponds with the present distribution of conifer (pine-oak) and broadleaved (oak-pine) forests in the valley and can be taken as a marker zone to infer palaeoecological changes. The sub-alpine and alpine krummholz, Juniperus and Ericaceae are found autochthonous in their pollen distribution that can serve as good indicators of relative tree-line and glacier dynamics in past. This pollen-vegetation relationship dataset could be an analogue for the interpretation of fossil pollen records in terms of extant vegetation in the mountain regions.
Structural Analysis of Lineaments Surrounding the Kailana-Takhat Sagar Reservoir and its Impact on Rising Ground Water Levels in Jodhpur
Authors: Menon Rajeev , Mysaiah D. , Kumar P. Senthil , Prasanna Lakshmi K. Jaya 
Published: June 2021

Abstract
Jodhpur city has been experiencing a significant rise in ground water levels leading to inundation in recent years. Previous studies suggested that ground water flow through a set of E-W trending lineaments from the Kailana-Takhat Sagar reservoir to the city areas was causative for the rise of ground water in the city. Therefore, the present study focuses on the role of the lineaments surrounding the reservoir in facilitating ground water flow to the city areas. Our exercise involved analysis of lineaments using high-resolution satellite images followed by geological and geophysical mapping. In the satellite images, a majority of the lineaments are oriented in the NNE-SSW to NE-SW directions with no connectivity to the city areas. A few lineaments with ESE-WNW orientations are present but these are small, without any connectivity to the affected areas in the city. Field studies involving 4800 strike/dip and fracture spacing measurements along the lineaments reveal the predominance of NNE-SSW to NE-SW oriented fracture systems similar to the lineaments. The lineaments surrounding the reservoir have a mean fracture spacing of ~15-30 cm. The fracture related secondary porosity is small (&lt; 1%), which is significantly lower than the bulk porosity of the Jodhpur sandstone (8.4 %) which is abundant in the affected city areas. Multichannel analysis of surface waves studies at twenty earmarked sites across the lineaments did not reveal any major fracture in the subsurface up to a depth of 35 meters, thereby corroborating the findings that the structural lineaments abounding the Kailana-Takhat Sagar reservoir cannot serve as ground water conduits for transporting ground water to the inundated areas in Jodhpur.