bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fungi inhabiting attine ant colonies: reassessment of the genus Escovopsis and description of Luteomyces and Sympodiorosea gens. nov.
Authors: Montoya Quimi Vidaurre , Martiarena Maria Jesus Sutta , Bizarria Rodolfo , Gerardo Nicole Marie , Rodrigues Andre 
Published: August 2021

AbstractEscovopsis is a diverse group of fungi, which are considered specialized parasites of the fungal cultivars of fungus-growing ants. The lack of a suitable taxonomic framework and phylogenetic inconsistencies have long hampered Escovopsis research. The aim of this study is to reassess the genus Escovopsis using a taxonomic approach and a comprehensive multilocus phylogenetic analysis, in order to set the basis of the genus systematics and the stage for future Escovopsis research. Our results support the separation of Escovopsis into three distinct genera. In light of this, we redefine Escovopsis as a monophyletic clade whose main feature is to form terminal vesicles on conidiophores. Consequently, E. kreiselii and E. trichodermoides were recombined into two new genera, Sympodiorosea and Luteomyces, as S. kreiselii and L. trichodermoides, respectively. This study expands our understanding of the systematics of Escovopsis and related genera, thereby facilitating future research on the evolutionary history, taxonomic diversity, and ecological roles of these inhabitants of the attine ant colonies.
Intraovarian platelet-rich plasma: current status
Authors: Elnashar Aboubakr Mohamed 
Published: August 2021

Abstract
Background
The successful use of PRP in regenerative medicine has led investigators to study its effect in the treatment of conditions like decreased ovarian reserve, poor responders, and premature ovarian insufficiency.

Objective
To review the uses of intraovarian PRP in reproductive medicine.

Methods
A literature search for English articles related to the uses of intraovarian PRP in reproductive medicine, including articles published in PubMed, from 2000 to April 2021.

Results
Seventeen studies: No RCT. Studies were classified according to indication. (1) For diminished ovarian reserve: 6 studies including 369 patients. (2). For poor responders: 3 case series studies including 41 patients with an improvement in ovarian response. (3) For premature ovarian insufficiency: 8 studies including 373 patients. Ovarian reserve markers were the outcome of all studies with conflicting results. LBR was not determined in the majority of studies.

Conclusion
Intraovarian PRP for diminished ovarian reserve, poor ovarian response, or POI is still experimental. Well-designed, large RCTS to confirm its efficacy and safety are required.
Molecular understanding of postharvest flower opening and senescence
Authors: Sun Xiaoming , Qin Meizhu , Yu Qin , Huang Ziwei , Xiao Yue , Li Yang , Ma Nan , Gao Junping 
Published: August 2021

AbstractFlowers are key organs in many ornamental plants, and various phases of flower development impact their economic value. The final stage of petal development is associated with flower senescence, which is an irreversible process involving programmed cell death, and premature senescence of cut flowers often results in major losses in quality during postharvest handling. Flower opening and senescence are two sequential processes. As flowers open, the stamens are exposed to attract pollinators. Once pollination occurs, flower senescence is initiated. Both the opening and senescence processes are regulated by a range of endogenous phytohormones and environmental factors. Ethylene acts as a central regulator for the ethylene-sensitive flowers. Other phytohormones, including auxin, gibberellin, cytokinin, jasmonic acid and abscisic acid, are also involved in the control of petal expansion and senescence. Water status also directly influences postharvest flower opening, while pollination is a key event in initiating the onset flower senescence. Here, we review the current understanding of flower opening and senescence, and propose future research directions, such as the study of interactions between hormonal and environmental signals, the application of new technology, and interdisciplinary research.
Attribute analyses of acoustic emissions in hydraulic fracturing
Authors: Acosta Juan Camilo , Dang Son T. , Sondergeld Carl H. , Rai Chandra S. 
Published: August 2021

Hydraulic fracturing (HF) and horizontal drilling are essential to the development of shale gas and oil. Production depends on the stimulation success. During fracture initiation, propagation, and closure, cracks emit acoustic waves; these can be monitored in real time as microseismics in the field and as acoustic emissions (AEs) in the laboratory. AEs are the laboratory equivalent of field-scale microseismics and contain detailed information about HF fracture mechanics. The number of acoustic events correlates with the number of induced fractures and hence the stimulation volume. Three HF protocols under dry conditions were carried out on Tennessee sandstone: (1) a constant injection rate, (2) a precyclic injection, and (3) a variable-rate injection test. All three tests were performed under the same principal stress conditions: vertical stress of 10.3 MPa (1500 psi), minimum horizontal stress of 3.5 MPa (500 psi), and maximum horizontal stress of 20.7 MPa (3000 psi). In total, 16 piezoelectric transducers were mounted around a cylindrical sample to record the AEs. We have performed postsignal processing to extract AE event attributes, including the amplitudes, signal-to-noise ratio, arrival time, event location (with the velocity-anisotropy input), and frequency analyses. The AE events associated with the constant-rate injection test possessed the lowest frequencies (150–270 kHz). The variable-rate test AE events possessed higher frequencies (160–310 kHz), whereas the precyclic injection had events with the highest frequencies, peaking at 330 kHz. Acoustic events before failure had lower amplitudes, but higher frequency compared to those recorded postbreakdown, suggesting different failure modes. Precyclic injection induced the greatest number of locatable events before and after failure.
Moths sense but do not learn flower odors with their proboscis during flower investigation
Authors: Adam Elisabeth , Hansson Bill S. , Knaden Markus 
Published: August 2021

ABSTRACTInsect pollinators, such as the tobacco hawkmoth Manduca sexta, are known for locating flowers and learning floral odors by using their antennae. A recent study revealed, however, that the tobacco hawkmoth additionally possesses olfactory sensilla at the tip of its proboscis. Here, we asked whether this second ‘nose’ of the hawkmoth is involved in odor learning, similar to the antennae. We first show that M. sexta foraging efficiency at Nicotiana attenuata flowers increases with experience. This raises the question whether olfactory learning with the proboscis plays a role during flower handling. By rewarding the moths at an artificial flower, we show that, although moths learn an odor easily when they perceive it with their antennae, experiencing the odor just with the proboscis is not sufficient for odor learning. Furthermore, experiencing the odor with the antennae during training does not affect the behavior of the moths when they later detect the learned odor with the proboscis only. Therefore, there seems to be no cross-talk between the antennae and proboscis, and information learnt by the antennae cannot be retrieved by the proboscis.
MiRNA-1202 promotes the TGF-β1-induced proliferation, differentiation and collagen production of cardiac fibroblasts by targeting nNOS
Authors: Xiao Jingwen , Zhang Yan , Tang Yuan , Dai Hengfen , OuYang Yu , Li Chuanchuan , Yu Meiqin 
Published: August 2021

BackgroundAtrial fibrillation (AF) is a clinically common arrhythmia that affects human health. Myocardial fibrosis serves as an important contributor to AF. Recently, miRNA-1202 have been reported to be up-regulated in AF. However, the role of miRNA-1202 and its mechanism in myocardial fibrosis remain unclear.MethodsHuman cardiac fibroblasts (HCFs) were used to construct a fibrosis model by TGF-β1 induction. The expression of miR-1202 was measured by qRT-PCR. Cell proliferation was assessed by CCK-8 assays. Protein expression levels were measured by western blot. Collagen accumulation was measured by ELISA. The relationship between miR-1202 and nNOS was investigated by luciferase reporter assays.ResultsMiR-1202 expression was obviously increased in HCFs and was both time- and dose-independent. MiR-1202 could increase the proliferation and collagen I, collagen III, and α-SMA levels with or without TGF-β1. MiR-1202 could also increase TGF-β1 and p-Smad2/3 protein levels in comparison to the control group. However, they were obviously decreased after inhibitor transfection. MiR-1202 targets nNOS for negative regulation of HCFs fibrosis by decreasing cell differentiation, collagen deposition and the activity of the TGF-β1/Smad2/3 pathway. Co-transfection of miR-1202 inhibitor and siRNA of nNOS inhibited nNOS protein expression, thereby enhancing the HCFs proliferation. Furthermore, co-transfection of the miR-1202 inhibitor and siRNA of nNOS significantly promoted collagen I, collagen III, TGF-β1, Smad2/3 and α-SMA protein expression and Smad2/3 protein phosphorylation. These findings suggested that miR-1202 promotes HCFs transformation to a pro-fibrotic phenotype by targeting nNOS through activating the TGF-β1/Smad2/3 pathway.
COVID-19 related psychological distress and fears among mothers and pregnant women in Saudi Arabia
Authors: Meraya Abdulkarim M. , Syed Mamoon H. , Yasmeen Ayesha , Mubaraki Amal A. , Kariry Hadi Dhafer , Maabouj Wafaa , Moraya Dhaifallah , Makeen Hafiz A. 
Published: August 2021

Objectives
This study objectives were to investigate maternal psychological distress, mothers’ fear of their children contracting COVID-19, mothers’ perceptions of the information available regarding children and COVID-19, changes in children’s behavior during lockdown, and concerns of pregnant women in Saudi Arabia.

Methods
This cross-sectional study surveyed women aged 18 years and older who either had children under 10 years of age or were pregnant at the time of the survey. The outcomes included psychological distress, mothers’ fear of their children contracting COVID-19, change in children’s behaviors during COVID-19 lockdown and pregnant women’s concerns. Multivariable ordinary least squares regression models were employed to examine the adjusted associations between sociodemographic factors and psychological distress, as well as fear of COVID-19.

Results
Of 628 women, 11.8% (n = 74) were pregnant at the time of survey. Most of the pregnant women (89.2%, n = 66) had some degree of concerns about their unborn babies getting infected during delivery in the hospital. Among mothers of children under 10 years of age (n = 564), half (n = 282) reported change in their children’s behavior during the lockdown. Most mothers and pregnant women (94.9%, n = 569) had some degree of psychological distress. Mothers and pregnant women with a college degree had significantly lower psychological distress (β = -1.346; p = 0.014) than women with a high school education or less. Similarly, mothers and pregnant women with monthly family income ≥ US$ 1,333 had lower psychological distress than those with < US$ 1,333. Women with pre-existing chronic physical (β = 2.424; p < 0.001) or mental (β = 4.733; p < 0.001) conditions had higher psychological distress than those without these conditions. Having children in the house was a contributory factor for higher psychological distress. For example, mothers with one child (β = 2.602; p = 0.007) had significantly higher psychological distress compared to expectant mothers without children in the house.

Conclusions
Most mothers and expectant mothers in our study had moderate to high levels of psychological distress during the COVID-19 pandemic outbreak in Saudi Arabia. Education, family income and chronic mental and physical conditions were associated with high psychological distress in Saudi Arabia during COVID-19.
Using an integrated knowledge translation approach to inform a pilot feasibility randomized controlled trial on peer support for individuals with traumatic brain injury: A qualitative descriptive study
Authors: Lau Stephanie K. C. , Luong Dorothy , Sweet Shane N. , Bayley Mark , Levy Ben B. , Kastner Monika , Nelson Michelle L. A. , Salbach Nancy M. , Jaglal Susan B. , Shepherd John , Wilcock Ruth , Thoms Carla , Munce Sarah E. P. 
Published: August 2021

Introduction
Traumatic brain injury (TBI) is estimated to affect 10 million people annually, making it a leading cause of morbidity and mortality worldwide. One cost-effective intervention that has been shown to minimize some of the negative sequelae after TBI is peer support. However, the evidence supporting the benefits of peer support for individuals with TBI is sparse and of low quality. Integrated knowledge translation (iKT) may be one approach to optimizing the evaluation of peer support programs among individuals with TBI. Therefore, the objectives are: (1) To understand key informants’ perspectives of the barriers and facilitators of participating in peer support research and programs among individuals with TBI; (2) to understand key informants’ perspectives on the perceived impacts of peer support programs on individuals with TBI; and, (3) to demonstrate how an iKT approach can inform the development and implementation of a pilot feasibility randomized controlled trial (RCT).

Methods
A qualitative descriptive approach using one-on-one semi-structured interviews was used. Purposive sampling of 22 key informants included 8 peer support mentors, 4 individuals with TBI who received peer support, 3 caregivers of individuals with TBI, 4 peer support program staff, and 3 academics in peer support and/or TBI.

Results
There were five main themes related to the barriers and facilitators to participating in peer support research and programs: knowledge, awareness, and communication; logistics of participating; readiness and motivation to participate; need for clear expectations; and matching. There were three main themes related to the perceived impact of peer support: acceptance, community, social experiences; vicarious experience/learning through others: shared experiences, role-modelling, encouragement; and “I feel better.” Discussions with our Research Partner led to several significant adaptations to our trial protocol, including removing the twice/week intervention arm, shortening of the length of trial, and changing the measure for the community integration outcome.

Discussion/Conclusion
This is the first study to use an iKT approach to inform a trial protocol and the first to assess the barriers and facilitators to participating in peer support research.
Progression From Antral G-Cell Hyperplasia to Gastric Neuroendocrine Tumor in a Patient With Autoimmune Gastritis
Authors: Brown Patrick , Tetali Bhavana , Suresh Suraj , Varma Adarsh 
Published: August 2021

ABSTRACT
Autoimmune metaplastic atrophic gastritis is caused by immune-mediated destruction of gastric parietal cells. This leads to the absence of gastric acid production, which causes compensatory hyperplasia of gastric antral G-cells leading to hypergastrinemia. The excess gastrin binds to enterochromaffin-like cells causing hyperplasia, which may progress to dysplasia and rarely to gastric neuroendocrine tumors. We present a rare case of autoimmune metaplastic atrophic gastritis associated with G-cell hyperplasia showing the full developmental spectrum of enterochromaffin-like cell proliferation from hyperplasia to dysplasia to neuroendocrine tumor.
The Number of Interstitial Cells of Cajal Differs Among Different Subtypes of Achalasia and is Related to Patients' Prognosis
Authors: Chen Songfeng , Zhang Mengyu , Liang Mengya , Tan Niandi , Cui Yi , Wang Jinhui , Xin Xiangbin , Ye Ziyin , Zhuang Qianjun , Xiao Yinglian 
Published: August 2021

INTRODUCTION:
Achalasia is a primary esophageal motility disorder with heterogeneous manometric subtypes and prognosis, characterized by degeneration of the esophageal myenteric plexus, and reduction in interstitial cells of Cajal (ICCs). This study aimed to explore the histopathologic characteristics of lower esophageal sphincter (LES) muscle from patients with achalasia with different subtypes and different prognosis.

METHODS:
We examined specimens of LES muscle from 122 patients with achalasia who underwent peroral endoscopic myotomy and from 10 control patients who underwent esophagectomy for esophageal cancer. Hematoxylin–eosin staining was performed to assess inflammation infiltration, fibrosis, and atrophy. Specific immunohistochemical staining was performed to identify ICCs and neuronal nitric oxide synthase (nNOS).

RESULTS:
The number of ICCs in patients with type I achalasia was significantly lower than that in patients with type II achalasia, followed by that in control patients (type I vs type II vs control group= 0.4 vs 1.2 vs 9.5; P < 0.001). The number of nNOS-positive cells was significantly lower in patients with achalasia than that in control patients (type I vs type II vs control group = 0.0 vs 0.0 vs 8.0; P < 0.001). Nonrecurrent group had significantly more ICCs than recurrent group (type I: nonrecurrent vs recurrent = 1.0 vs 0.1; P = 0.010; type II: nonrecurrent vs recurrent = 2.0 vs 0.4; P = 0.004).

DISCUSSION:
ICCs and nNOS-positive cells reduced significantly in LES muscle of patients with achalasia. The number of ICCs differed among different achalasia subtypes and was related to patients' clinical prognosis.
PROPENSÃO À MODIFICAÇÃO DE RIOS A PARTIR DA SENSITIVIDADE DE ESTILOS FLUVIAIS EM UMA BACIA HIDROGRÁFICA NO SEMIÁRIDO DA PARAÍBA (BRASIL)
Authors: Rodrigues Jeferson Mauricio , Souza Jonas Otaviano Praça de , Xavier Rafael Albuquerque 
Published: August 2021

O conceito de sensitividade se perdeu nos últimos anos entre os trabalhos que tratam sobre a temática de evolução e recuperação de ambientes fluviais semiáridos. Todavia, o conceito e metodologia de sensitividade permite identificar e compreender trechos fluviais que apresentam propensão à mudança. Pesquisas feitas no semiárido australiano pelos pesquisadores Brierley e Friys indicam que a metodologia de sensitividade permite avaliar a propensão à modificação de rios a partir da análise de geoindicadores e seus respectivos subgeoindicadores. Foram analisados alguns geoindicadores que permitiram apontar as possíveis alterações no ambiente fluvial de cada estilo que foram: a morfologia do canal, planta do canal e as características de leito. Foi possível identificar seis estilos fluviais, conforme suas características de vale, unidades geomórficas e textura. Os estilos confinados apresentaram baixa sensitividade por conta dos controles nas margens e leito rochosos. O EFNCRC foi o estilo que apresentou alta sensitividade, por conta da energia de fluxo moderada e leito e margens móveis. Por fim, foi feita uma análise estatística com base nos dados do índice de sinuosidade aplicado em cada estilo que propiciou maior entendimento acerca das diferentes alterações na forma em planta dos estilos fluviais analisados, buscando quantificar os ajustes fluviais.
Economic Feasibility of Solar Irrigation Pumps: A Study of Northern Bangladesh
Authors: Islam Md. Tawhidul , Hossain Md. Elias 
Published: August 2021

Bangladesh is the most densely populated country in the world. With a total population of around 165 million, the country has constantly been facing food security challenges and other problems. Therefore, increasing food production is one of the feasible solutions to this challenge, and proper agricultural land use for food production bears critical importance. Adopting sustainable irrigation systems and viable technologies would be vital for ensuring efficient use of agricultural land in Bangladesh to safeguard the country's food security. Solar irrigation pumps (SIPs) can be a reliable option in this regard. However, Bangladesh has experienced a prolonged growth rate of SIP installation in the last decade. The countryhas set a target to install 10000 SIPs by the year 2027, albeit it is a tiny share of the 1.57 million conventional irrigation pumps operating in the country. This study aims to investigate the economic feasibility of the SIPs operating in the northern region of Bangladesh in terms of estimating financial feasibility and environmental benefits. The study is mainly based on primary data collected from the users of SIPs from two Upazilas of Dinajpur and Rangpur districts. A total of 14 SIPs, categorized into large, medium, and small pumps, are selected randomly from the available SIPs in the study areas. The financial analysis reveals that small SIPs are the most profitable option (20% IRR) for investment. Large SIPs are moderately profitable (10% IRR), and their profitability can be improved (10.50% IRR) by introducing additional uses of solar energy. However, medium SIPs are the worst (5% IRR) option for investment. In the study areas, large and medium SIPs are designed for the 'fees for service model', and small SIPs are designed for the 'fees for ownership model'. It is found that the 'fees for ownership model' is more profitable than the 'fees for service model'. Moreover, the net environmental benefit for all SIPs is found almost equal to the given subsidy for installing them. Also, the net environmental benefit per kilowatt peak (kWp) is highest for the small SIPs. This paper recommends that additional use (e.g., husking, grinding, supply excess electricity to grid, and so on) of solar energy can improve the profitability of investmenton SIPs. Further, the government should continue giving grants for installing SIPs and promote 'fees for ownership model' (small SIPs) for personal use. It would speed up the dissemination rate of SIPs and help increase the country's agricultural production and improve the environmental conditions.
Sub-terahertz (THz) antenna for Internet of Things and 6G Communication
Authors: Vettikalladi Hamsakutty , Sethi Waleed Tariq , Ko Wonsuk 
Published: August 2021

AbstractSub-terahertz (THz) technology is expected to deliver exceptional data rates for future sixth generation wireless communication systems especially for intelligent communication among devices falling under the Internet of Things (IoT) category. Moving from current 5G millimeter wave (mmW) technology towards THz spectrum will eventually provide unprecedented solutions that will guarantee higher transmission rates and channel capacity for any wireless communication system. With various electronic and wireless components working together to fulfill this promise, high gain antennas having compact profile is one such technology that will aid in achieving sub-THz communication while offering low path and power losses with reliable and fast data transfers. In this context, this work proposes a novel deformed patch antenna operating in the sub-THz spectrum i.e. at 300 GHz band. The proposed antenna is fed via a microstrip line following the proximity coupled feeding technique. Utilizing this technique provides a wide impedance bandwidth with a broadside radiation pattern having minimum side lobe levels of around −12 dB and a directivity of 10–15 dBi for the single and array elements respectively. The proposed design has a small footprint of 1.5 × 1.5 × 0.06 mm3for the single element while the array element has dimensions of 6 × 5 × 0.06 mm3. Both the designs have been simulated in Computer Simulation Technology-Microwave Studio (CST-MWS) and the results verified via high-frequency structure simulator (HFSS) simulator. The results confirm the viability of the proposed designs to be potential candidates for future sixth generation and IoT based applications.