bluuebunny/crossref_metadata_2025_split huggingface dataset:
La Convergencia en los procesos de Certificación ISO y Acreditación CONAIC en Instituciones de Educación Superior IES.
Authors: Ortega Hernández Carmen C. , Bermúdez Lazos Jorge A. , Ristori Cueto David 
Published: September 2021

Actualmente los procesos de Certificación ISO y Acreditación CONAIC juegan un papel muy importante en laGestión de la Calidad de los productos y servicios que las Instituciones de Educación Superior (IES) ofertan a la sociedad. Es por ello, que sin distinción al sector que pertenezca, sea privado o público han comprendido que someterse a los procesos de evaluación y cumplir con una lista extensa y detallada de requerimientos que solicitan las organizaciones, promueven un retorno de inversión orientado en beneficios a la misma institución. Este documento, presenta una nueva visión de las similitudes que existen entre los componentes y la estructura de ambos procesos, entre las ventajas se puede mencionar que las Instituciones que ya aprobaron una acreditación pueden someterse con mayor confianza a una certificación, o viceversa; y además, promueve áreas de oportunidades para fortalecer el mecanismo de evaluación del CONAIC.
Currently the process of ISO Certification and Accreditation CONAIC play an important role in the quality management of products and services that Higher Education Institutions (IES) offer to society. That is why, regardless the sector they belong, whether private or public have understood that undergo evaluation processes and meet an extensive and detailed list of requirements applying organizations, promote a return -oriented investment in benefits to same institution. This paper presents a new point of view in the similarities that exist in the components and structure of both processes, the advantages may be mentioned that the institutions that have already approved accreditation can undergo more confidence to certification, or vice versa ; and also it promotes areas of opportunity to strengthen the assessment mechanism CONAIC .
KORELASI KARAKTERISTIK EKOLOGI TEMPAT PERINDUKAN VEKTOR MALARIA DENGAN KEPADATAN LARVA Anopheles Spp DI DESA HANURA KABUPATEN PESAWARAN PROVINSI LAMPUNG 2019
Authors: Putri Devita Febriani , Husna Ismalia , Hermawan Dessy , Firmansyah Firmansyah 
Published: September 2021

Malaria adalah salah satu penyakit infeksi yang ditularkan oleh nyamuk Anopheles sp betina. Berdasarkan Profil Kesehatan Kabupaten Pesawaran diketahui bahwa terdapat sebanyak 3.123 kasus malaria. Kasus positif malaria hanya terjadi di 3 wilayah kerja puskesmas yaitu Puskesmas Hanura (2.528 kasus), Kabupaten Pesawaran menjadi daerah yang endemis malaria karena kondisi alamnya. Tujuan penelitian diketahui korelasi karakteristik ekologi tempat perindukan vektor malaria dengan kepadatan larva Anopheles spp. di Desa Hanura Kabupaten Pesawaran Tahun 2019. Jenis penelitian kuantitatif, rancangan deskriptif analitik dengan pendekatan cross sectional. Populasi seluruh tempat perindukan nyamuk yang potensial sebanyak 3 lokasi. Sampel sebanyak 3 lokasi dengan teknik purposive sampling. Pengambilan data menggunakan lembar observasi. Teknik analisis data menggunakan uji statistik pearson. Hasil penelitian lingkungan kimia tempat perindukan vektor malaria Anopheles spp di Desa Hanura memiliki rata – rata pH air 7,67, rata – rata salinitas air 3,47‰, dan rata – rata oksigen terlarut (DO) 2,7mg/L. Lingkungan fisika tempat perindukan vektor malaria Anopheles spp di Desa Hanura memiliki rata – rata suhu air 28,250C dan rata – rata kedalaman air 85 cm. Lingkungan biologi tempat perindukan vektor malaria Anopheles spp di Desa Hanura dengan ditemukannya jenis tumbuhan bakau, lumut, kelapa dan jenis hewan ikan, kepiting, keong, udang dan kecebong. Kepadatan larva nyamuk Anopheles spp di Desa Hanura 10,08 ekor. Kesimpulan lingkungan kimia, fisika dan biologi berkorelasi dengan kepadatan larva nyamuk Anopheles spp di Desa Sukajaya Lempasing dengan pH air (p=0,031, r = -0,622), salinitas air (p=0,085, r = 0,517), kadar oksigen (p=0,020, r = -0,657), suhu (p=0,021, r = -0,655), kedalaman (p= 0,000, r = -0,872), tanaman (p = 0,000, r = 0,878) dan hewan (p = 0,056, r = -0,563). Disarankan masyarakat untuk pemberantasan tempat perkembang biakan nyamuk melalui penebaran bibit ikan pemakan jentik.
Peningkatan Kemampuan Membaca Permulaan Siswa Kelas I Sd Negeri 10 Palangka Melalui Media Kartu Huruf
Authors: Susanti Priskila 
Published: September 2021

Penelitian ini bertujuan untuk mengetahui peningkatan hasil belajar siswa pada pembelajaran Bahasa Indonesia kelas I setelah menggunakan media Kartu dan Untuk mengetahui peningkatan hasil belajar siswa pada pembelajaran Bahasa Indonesia kelas I setelah menggunakan media Kartu Huruf.
Penelitian yang dipakai adalah Penelitian Tindakan Kelas, Subjek tindakan pada penelitian ini adalah siswa-siswi kelas I SD Negeri 10 Palangka. Jumlah seluuruh subjek penelitian 10 orang siswa.
Kesimpulan dari penilaian ini adalah bahwa Model Pembelajaran metode Media Kartu Huruf dapat meningkatkan nilai hasil belajar siswa pada mata pelajaran Bahasa Indonesia di kelas I SD Negeri 10 Palangka.Refleksi Tindakan Siklus II Berdasarkan hasil dari evaluasi/tes akhir, lembar observasi guru dan siswa pada siklus II ini dapat disimpulkan bahwa tindakan yang dilakukan telah maksimal. Siswa merasa senang dan antusias dalam mengikuti pembelajaran karena dengan penerapan media yang menarik anak tidak merasa bosan dalan kegiatan pembelajaran seperti kegiatan bermain.Sebagian besar siswa sudah dapat membaca huruf, suku kata, kata, dan kalimat sederhana dengan lancar serta penggunaan lafal yang benar.
Meningkatkan Hasil Belajar Ipa Melalui Metode Pemecahan Masalah (Problem Solving Method)
Authors: Rokhani Siti 
Published: September 2021

Tujuan dari pelaksanaan PTK ini adalah untuk meningkatkan hasil belajar IPA melalui penerapan metode pemecahan masalah pada siswa kelas IX-B SMPS Muhammadiyah Buntok dalam pembelajaran IPA. PTK ini diharapkan dapat memberikan manfaat bagi siswa maupun guru. Manfaat bagi siswa, yaitu dapat membantu siswa agar lebih mudah dalam memahami materi pelajaran. Sedangkan manfaat bagi guru antara lain dapat memberikan alternatif pilihan strategi pembelajaran yang efektif dalam meningkatkan kualitas proses dan hasil belajar siswa dalam pembelajaran IPA.
Data hasil observasi pembelajaran dianalisis bersama-sama dengan mitra kolaborasi, kemudian ditafsirkan berdasarkan kajian pustaka dan pengalaman guru peneliti dan guru mitra. Sedangkan hasil belajar siswa dianalisis berdasarkan ketentuan ketuntasan belajar, yaitu dengan membandingkan nilai yang diperoleh siswa dengan Kriteria Ketuntasan Minimal (KKM). Dalam penelitian ini ditetapkan nilai KKM adalah 70. Seorang siswa dinyatakan mencapai ketuntasan belajar jika memperoleh nilai lebih dari/sama dengan 70.
Hasil penelitian ini menunjukkan terjadinya peningkatan yang signifikan baik pada keaktifan siswa maupun pada nilai hasil belajarnya. Peningkatan keaktifan siswa ditunjukkan dengan terjadinya peningkatan jumlah siswa yang aktif dalam proses pembelajaran pada tiap-tiap siklus. Sedang peningkatan hasil belajar siswa dibuktikan dengan terjadinya peningkatan jumlah siswa yang dapat memperoleh nilai lebih dari atau sama dengan KKM, yaitu sebesar 78,57% pada siklus I meningkat menjadi 96,42% pada siklus II. Disamping itu nilai rata-rata hasil belajar siswa juga mengalami peningkatan dari 74,99 pada siklus I menjadi 90,85 pada siklus II.
KOMPRES HANGAT DAN AROMATERAPI LAVENDER DAPAT MENGURANGI NYERI PUNGGUNG PADA IBU HAMIL TRIMESTER III
Authors: Wulandari Dyah Ayu , Mendrofa Fery Agusman , Safitri Ifana 
Published: September 2021

Ibu hamil trimester III seringkali mengalami ketidaknyamanan yang salah satu diantaranya adalah nyeri punggung. Nyeri punggung merupakan nyeri yang terjadi pada area lumbosacral. Berdasarkan data yang diperoleh dari hasil survey pendahuluan di Puskesmas Bangetayu Semarang melaporkan pada tahun 2019 kunjungan K1 dan K4 mencapai 2.534 ibu hamil, keluhan nyeri punggung sebesar 35% pada trimester III. Tujuan penelitian ini untuk mengetahui pengaruh pemberian terapi kompres hangat dan aromaterapi lavender terhadap penurunan nyeri punggung ibu hamil trimester III di Wilayah Puskesmas Bangetayu Semarang.
Jenis penelitian pra-eksperimen. Teknik pengambilan sampel menggunakan non-probability sampling dengan jumlah sampel sebanyak 18 orang. Median nyeri punggung ibu hamil Trimester III sebelum diberikan kompres hangat adalah 6.00, sedangkan sesudah diberikan kompres hangat median 3.50. Median nyeri punggung ibu hamil Trimester III sebelum diberikan aromaterapi lavender adalah 3.50, sedangkan sesudah diberikan aromaterapi lavender, dengan median 3.50. Ada pengaruh pemberian kompres hangat dan aromaterap lavender terhadap nyeri punggung ibu hamil trimester III di Wilayah Puskesmas Bangetayu Semarang (p-value=0,000). Simpulannya adalah kompres hangat dan aroamterapi lavender efektif menurunkan nyeri punggung ibu hamil trimester III di Wilayah Puskesmas Bangetayu Semarang.
Kata kunci : Kompres hangat, aromaterapi lavender, nyeri punggung, kehamilan trimester III
How COVID-19 Will Change Health, Hospitality and Senior Facility Design
Authors: Shepley McCuskey Mardelle , Kolakowski Heather , Ziebarth Nicolas , Valenzuela-Mendoza Ellie 
Published: September 2021

Background: Based on recent experiences with the COVID-19 pandemic, designers and design researchers are crafting guidelines for the development of future environments. In this context, this paper focuses on future best practices regarding environments for health, hospitality and senior care.Methods: An extensive literature review was conducted, the results of which were distributed to a group of experts (N=12) specializing in health, hospitality and design. After receiving their input, expert focus groups were conducted to further explore the proposed concepts. The document was revised based on the contributions of these field experts, resubmitted for additional input, and ultimately summarized in this paper.Results: Based on the literature review and expert input, dozens of recommendations were made regarding post-COVID health, hospitality and seniors environments. Healthcare facilities will require additional space, access to the outdoors, service hubs, and additional infrastructure to all conversion of garages for emergency use. Hospitality settings will employ new cleaning methods, use of robotics, improved HVAC, Wellness programming, workspace options, and flexible food service operations. Senior facilities will engage more technology, socially distance visiting facilities, increase access to nature, and smaller scale residential clusters.Discussion: By considering health and hospitality simultaneously, we come to understand the symbiotic benefits of applying goals from one sector to the other. Senior living environments are an excellent example of this approach in action. By implementing some of the proposed design recommendations generated by this research, we will be better prepared to face future challenges.
Polydatin Ameliorates Osteoporosis via Suppression of the Mitogen-Activated Protein Kinase Signaling Pathway
Authors: Lin Ze , Xiong Yuan , Hu Yiqiang , Chen Lang , Panayi Adriana C. , Xue Hang , Zhou Wu , Yan Chenchen , Hu Liangcong , Xie Xudong , Sun Yun , Mi Bobin , Liu Guohui 
Published: September 2021

Purpose: Polydatin (POL) is a natural active compound found in Polygonum multiflorum with reported anti-oxidant and antiviral effects. With the aging population there has been a stark increase in the prevalence of osteoporosis (OP), rendering it an imposing public health issue. The potential effect of POL as a therapy for OP remains unclear. Therefore, we sought to investigate the therapeutic effect of POL in OP and to elucidate the underlying signaling mechanisms in its regulatory process.Methods: The POL-targeted genes interaction network was constructed using the Search Tool for Interacting Chemicals (STITCH) database, and the shared Kyoto Encyclopedia of Genes and Genomes (KEGG). Pathways involved in OP and POL-targeted genes were identified. Quantitative real-time PCR (qRT-PCR) and enzyme-linked immunosorbent assay (ELISA) were performed to evaluate the osteogenic genes and the phosphorylation level in pre-osteoblastic cells. In addition, ALP and alizarin red staining was used to test the effect of POL on extracellular matrix mineralization.Results: Twenty-seven KEGG pathways shared between POL-related genes and OP were identified. MAPK signaling was identified as a potential key mechanism. In vitro results highlighted a definitive anti-OP effect of POL. The phosphorylation levels of MAPK signaling, including p38α, ERK1/2, and JNK, were significantly decreased in this regulatory process.Conclusion: Our results suggest that POL has a promising therapeutic effect in OP. MAPK signaling may be the underlying mechanism in this effect, providing a novel sight in discovering new drugs for OP.
Preparation of CdS@C Photocatalyst Using Phytoaccumulation Cd Recycled From Contaminated Wastewater
Authors: Li Jia-Xin , Zhang Rou-Lan , Pan Zi-Jian , Liao Yan , Xiong Chao-Bin , Chen Ming-Li , Huang Rong , Pan Xiao-Hong , Chen Zhi 
Published: September 2021

Cadmium is one of the most toxic heavy metal contaminants in soils and water bodies and poses a serious threat to ecosystems and humans. However, cadmium is also an important resource widely used in many industries. The recovery of cadmium in the form of high-value products is considered as an ideal disposal strategy for Cd-contaminated environments. In this work, Pistia stratiotes was used to recycle cadmium from wastewaters through phytoaccumulation and then transformed into carbon-supported cadmium sulfide photocatalyst (CdS@C) through carbonization and hydrothermal reaction. The CdS@C photocatalyst contained a mixture of cubic and hexagonal CdS with lower band gap energy (2.14 eV) and high electron-hole separation efficiency, suggesting an excellent photoresponse ability and photocatalytic efficiency. The impressive stability and photocatalytic performance of CdS@C were demonstrated in efficient photodegradation of organic pollutants. •OH and O2•- were confirmed as the major active species for organic pollutants degradation during CdS@C photocatalysis. This work provides new insights into addressing Cd contaminated water bodies and upcycling in the form of photocatalyst.
Selective Hydrogenation of the Carbonyls in Furfural and 5-Hydroxymethylfurfural Catalyzed by PtNi Alloy Supported on SBA-15 in Aqueous Solution Under Mild Conditions
Authors: Gao Ge , Jiang Zhicheng , Hu Changwei 
Published: September 2021

Valuable furfuryl alcohol (FFA) and 2,5-dihydroxymethylfuran (DHMF) could be produced by selective hydrogenation of biomass-derived furfural (FF) and 5-hydroxymethylfurfural (HMF) with high atom economy. In this study, SBA-15 (a kind of mesoporous silica molecular sieve)-supported low metal loading (3 wt% total metal content) PtNi alloy catalyst (PtNi/SBA-15) was synthesized via two steps, including the generation of PtNi alloy by hydrothermal method, and the immobilization of PtNi alloy on SBA-15. PtNi/SBA-15 has ordered mesoporous structure with high surface area, and high dispersion of the PtNi alloy with the formation of Ptδ−-Niδ+ surface pairs on SBA-15, which benefit hydrogen activation and selective carbonyl hydrogenation. The selective hydrogenation of FF and HMF over PtNi/SBA-15 in water solvent at 303 K with 1.5 MPa H2 within 2 h, could respectively yield 64.6% FFA with 77.0% selectivity, and 68.2% DHMF with 81.9% selectivity. Besides, PtNi/SBA-15 exhibited a satisfactory water resistance and stability after recycling at least five runs.
In Vitro Evaluation of Lavandula angustifolia Essential Oil on Anti-Toxoplasma Activity
Authors: Yao Na , He Jia-Kang , Pan Ming , Hou Zhao-Feng , Xu Jin-Jun , Yang Yi , Tao Jian-Ping , Huang Si-Yang 
Published: September 2021

The current methods of treating toxoplasmosis have a number of side effects, and these therapies are only effective against the acute stage of the disease. Thus, development of new low toxicity and efficient anti-Toxoplasma drugs is extremely important. Natural products are important sources for screening new drugs; among them, essential oils (EOs) have efficacy in anti-bacterial, anti-inflammatory, anti-insect, and other aspects. In this study, 16 EOs were screened for their anti-T. gondii activity. Lavandula angustifolia essential oil (La EO)was found to have an anti-parasitic effect on T. gondii. The cytotoxicity of La EO was firstly evaluated using the MTT assay on human foreskin fibroblast (HFF) cells, and then the anti-T. gondii activity was evaluated by plaque assay. Finally, the invasion experiment and electron microscope observation were used to study the mechanism of La EO in anti-toxoplasma activity. The results indicated that the CC50 of La EO was 4.48 mg/ml and that La EO had activity against T. gondii and the inhibition was in a dose-dependent manner under safe concentrations. La EO was able to reduce T. gondii invasion, which may be due to its detrimental effect on changes of the morphology of tachyzoites. These findings indicated that La EO could be a potential drug for treating toxoplasmosis.
Respiratory Motion-Registered Isotropic Whole-Heart T2 Mapping in Patients With Acute Non-ischemic Myocardial Injury
Authors: Dorniak Karolina , Di Sopra Lorenzo , Sabisz Agnieszka , Glinska Anna , Roy Christopher W. , Gorczewski Kamil , Piccini Davide , Yerly Jérôme , Jankowska Hanna , Fijałkowska Jadwiga , Szurowska Edyta , Stuber Matthias , van Heeswijk Ruud B. 
Published: September 2021

Background: T2 mapping is a magnetic resonance imaging technique that can be used to detect myocardial edema and inflammation. However, the focal nature of myocardial inflammation may render conventional 2D approaches suboptimal and make whole-heart isotropic 3D mapping desirable. While self-navigated 3D radial T2 mapping has been demonstrated to work well at a magnetic field strength of 3T, it results in too noisy maps at 1.5T. We therefore implemented a novel respiratory motion-resolved compressed-sensing reconstruction in order to improve the 3D T2 mapping precision and accuracy at 1.5T, and tested this in a heterogeneous patient cohort.Materials and Methods: Nine healthy volunteers and 25 consecutive patients with suspected acute non-ischemic myocardial injury (sarcoidosis, n = 19; systemic sclerosis, n = 2; acute graft rejection, n = 2, and myocarditis, n = 2) were included. The free-breathing T2 maps were acquired as three ECG-triggered T2-prepared 3D radial volumes. A respiratory motion-resolved reconstruction was followed by image registration of the respiratory states and pixel-wise T2 mapping. The resulting 3D maps were compared to routine 2D T2 maps. The T2 values of segments with and without late gadolinium enhancement (LGE) were compared in patients.Results: In the healthy volunteers, the myocardial T2 values obtained with the 2D and 3D techniques were similar (45.8 ± 1.8 vs. 46.8 ± 2.9 ms, respectively; P = 0.33). Conversely, in patients, T2 values did differ between 2D (46.7 ± 3.6 ms) and 3D techniques (50.1 ± 4.2 ms, P = 0.004). Moreover, with the 2D technique, T2 values of the LGE-positive segments were similar to those of the LGE-negative segments (T2LGE−= 46.2 ± 3.7 vs. T2LGE+ = 47.6 ± 4.1 ms; P = 0.49), whereas the 3D technique did show a significant difference (T2LGE− = 49.3 ± 6.7 vs. T2LGE+ = 52.6 ± 8.7 ms, P = 0.006).Conclusion: Respiratory motion-registered 3D radial imaging at 1.5T led to accurate isotropic 3D whole-heart T2 maps, both in the healthy volunteers and in a small patient cohort with suspected non-ischemic myocardial injury. Significantly higher T2 values were found in patients as compared to controls in 3D but not in 2D, suggestive of the technique's potential to increase the sensitivity of CMR at earlier stages of disease. Further study will be needed to demonstrate its accuracy.
Physical Activity and Risks of Cardiovascular Diseases: A Mendelian Randomization Study
Authors: Zhuo Chengui , Zhao Jianqiang , Chen Miao , Lu Yunlong 
Published: September 2021

Background: Although some observational studies have shown that physical activity may have a positive relationship with cardiovascular diseases, the causal effect remains uncertain. We conducted a Mendelian randomization (MR) study to identify the potential causal effect between physical activity and cardiovascular diseases.Methods: Summary statistics of genome-wide association studies on four physical activity phenotypes and cardiovascular diseases were utilized. MR analysis was performed using inverse-variance weighted (IVW) and multivariable MR. Multiple sensitivity analysis was further conducted to identify the robustness of our results.Results: Genetically predicted self-reported vigorous physical activity (VPA) was significantly associated with lower risk of myocardial infarction (IVW OR: 0.24, 95% CI: 0.08–0.68, p-value: 0.007). Additionally, the causal effect of VPA with myocardial infarction was robust after adjusting for several cardiovascular risk factors through using the multivariable MR. There were no apparent causal associations between physical activity with other cardiovascular diseases. Results were consistent with the sensitivity analysis.Conclusion: The present study supports a protective role of self-reported vigorous physical activity in the initiation of myocardial infarction and highlights the importance of activity levels of physical activity. Further studies are required to elucidate the potential biological pathways of physical activity with cardiovascular diseases.
Athlete's Heart in Asian Military Males: The CHIEF Heart Study
Authors: Liu Pang-Yen , Tsai Kun-Zhe , Lima Joao A. C. , Lavie Carl J. , Lin Gen-Min 
Published: September 2021

Background: Elite athlete's heart is characterized by a greater left ventricular mass indexed by body surface area (LVMI) and diastolic function; however previous studies are mainly conducted in non-Asian athletes compared to sedentary controls.Methods: This study included 1,388 male adults, aged 18–34 years, enrolled in the same unified 6-month physical training program in Taiwan. During the midterm exams of 2020, all trainees completed a 3-km run (endurance) test, and 577 were randomly selected to attend a 2-min push-up (muscular strength) test. Elite athletes were defined as the performance of each exercise falling one standard deviation above the mean (16%). Cardiac structure and function were measured by echocardiography and compared between elite and non-elite athletes. Multiple logistic regression analysis was used to determine the independent predictors of elite athlete status at each exercise modality.Results: As compared to non-elite controls, elite endurance athletes had greater LVMI (84.4 ± 13.6 vs. 80.5 ± 12.9 g/m2, p &lt; 0.001) and lateral mitral E'/A' ratio (2.37 ± 0.73 vs. 2.22 ± 0.76, p &lt; 0.01) with lower late diastolic A' (7.77 ± 2.16 vs. 8.30 ± 3.69 cm/s, p = 0.03). Elite strength athletes had greater LVMI (81.8 ± 11.4 vs. 77.5 ± 12.1, p = 0.004) and lateral mitral E'/A' ratio (2.36 ± 0.70 vs. 2.11 ± 0.71, p &lt; 0.01) with a greater early diastolic E' (19.30 ± 4.06 vs. 18.18 ± 4.05 cm/s, p = 0.02). Greater LVMI and lower heart rate were independent predictors of elite endurance athletes [odds ratio (OR) and 95% confidence intervals: 1.03 (1.02, 1.04) and 0.96 (0.95, 0.98), respectively]. Greater LVMI, lateral mitral E'/A' ratio and right ventricular systolic pressure were independent predictors of elite strength athletes [OR: 1.03 (1.01, 1.05), 1.50 (1.06, 2.12), and 1.12 (1.05, 1.19), respectively].Conclusions: Cardiac structural and functional characteristics differ between endurance and strength elite athletes. While greater LVMI predicts elite status in both groups of Asian athletes, consistent with findings from Western elite athletes, greater diastolic function, and right ventricular systolic pressure characterize strength elite athletes, while lower heart rate at rest predicts endurance elite athletic status.