bluuebunny/crossref_metadata_2025_split huggingface dataset:
One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice from SARS-CoV-2 upper and lower respiratory tract infection
Authors: Liu Ruikang , Americo Jeffrey L. , Cotter Catherine A. , Earl Patricia L. , Erez Noam , Peng Chen , Moss Bernard 
Published: March 2021

SignificanceVaccines are required to control COVID-19 during the current pandemic and possibly afterward. Recombinant nucleic acids, proteins, and virus vectors that stimulate immune responses to the SARS-CoV-2 S protein have provided protection in experimental animal and human clinical trials, although questions remain regarding their ability to prevent spread and the duration of immunity. The present study focuses on replication-restricted modified vaccinia virus Ankara (MVA), which has been shown to be a safe, immunogenic, and stable smallpox vaccine and a promising vaccine vector for other infectious diseases and cancer. In a transgenic mouse model, one or two injections of recombinant MVAs that express modified forms of S inhibited SARS-CoV-2 replication in the upper and lower respiratory tracts and prevented severe disease.
Case Report: Increasing the Frequency of Intramuscular Naltrexone Administration in a High Risk Patient with Opioid use Disorder
Authors: Wright Melissa , De Aquino Joao P. , Bystrak Tamara 
Published: March 2021

Background As the United States faces a national opioid crisis, opioid overdose deaths have significantly risen over the past decade. Patients with opioid use disorder, particularly those who use high-potency synthetic opioids, are at an increased risk of fatal opioid overdose. Alternative dosing strategies for the treatment of opioid use disorder must be considered in high-risk patients to prevent opioid overdose. Case One patient with opioid use disorder at high risk for overdose was treated with extended-release (XR) intramuscular (IM) naltrexone initially every 28 days, but was frequently reporting increased cravings during the week prior to the next injection being due. This patient's dose of XR IM naltrexone was then given at an increased dosing frequency of every 21–24 days for three months. Opioid craving suppression was achieved without clinical or laboratory evidence of side effects or hepatotoxicity. Discussion In patients with especially high risk of opioid overdose, consideration of novel dosing strategies for continuation of opioid abstinence is necessary. This is the first report demonstrating the short-term safety and efficacy of more frequent dosing of XR IM naltrexone. This case demonstrates that in select high-risk patients, more frequent dosing of XR IM naltrexone may be an effective strategy to reduce opioid cravings. Informed Consent The case was reviewed with the Intuition's Privacy Officer who informed the authors that informed consent could not be obtained by the patient's family members due to 38 U.S.C 7332 restrictions on protected information. This manuscript was de-identified and approved by the institution's local privacy officer for publication in accordance with institution policy.
A Rapid-Cycle Assessment Strategy for Understanding the Opioid Overdose Epidemic in Local Communities
Authors: Taubenberger Simone , Spencer Noelle , Chang Judy C. , Paul Nicole , Fabre Shelcie , Jagessar Bhavita , Trimble Daly , Roberto Raisa , Gill Puneet , Hulsey Eric , Arnold Aaron , Hacker Karen 
Published: March 2021

Background Certain communities in the United States experience greater opioid-involved overdose mortality than others. Interventions to stem overdose benefit from contextual understandings of communities’ needs and strengths in addressing the opioid crisis. This project aims to understand multiple stakeholder perspectives on the opioid epidemic in communities disproportionately affected by opioid-involved overdose mortality. Methods We performed a rapid-cycle qualitative assessment study utilizing in-depth interviews with community stakeholders and observations of community meetings in eight communities in Allegheny County, Pennsylvania, USA, disproportionately impacted by opioid-involved overdose mortality. Stakeholder categories included: current and past illicit users of opioids; medical and social service providers; emergency medical services; law enforcement; spouse or other family members of illicit users/former users of opioids; government officials; school officials; community members. Content analysis was utilized to identify themes and answer study questions. Regular feedback to stakeholders was provided to support targeted interventions. Results We performed semi-structured, in-depth interviews with 130 community stakeholders and 29 community meeting observations in 2018–2019. Participants perceived similar economic and social determinants as origins of the opioid overdose epidemic including lack of economic resources, loss of jobs, transient populations and dilapidated housing. However, they differed in their awareness of and attention to the epidemic. Awareness was dependent on the visibility of opioid use (presence of paraphernalia litter, location of drug users, media coverage, and relationship to users). Overall, there was good knowledge of naloxone for opioid overdose reversal but less knowledge about local syringe services programs. Perceptions of harm reduction efforts were ambivalent. Conclusions Members of communities impacted by the opioid epidemic perceived that economic downturn was a major factor in the opioid overdose epidemic. However, the varied beliefs within and between communities suggest that interventions need to be tailored according to the cultural norms of place.
International comparison CCQM-K41.2017, hydrogen sulfide in nitrogen
Authors: Kim D , Kim Y , Lee S , Kang J , Smeulders D , Wu H , Fuko J , Wijk Janneke I T van , Veen Adriaan M H van der , Tshilongo J , Jozela M , Leshabane N , Mphaphuli G , Ntsasa N G , Dias F , Costa C , Konopelko L , Efremova O , Bartlett S , Brewer P , Murugan A 
Published: March 2021

Main text
Hydrogen sulfide (H2S) is a poisonous gas which can paralyze the respiratory system, quickly leading to death. It is also a flammable gas, which will ignite explosively when exposed to heat, open flames or oxidizers. For these reasons, hydrogen sulfide is classified as a hazardous material. This comparison is a repeat of the key comparison of the "CCQM-K41 (2005)" and it is intended to compare the capabilities of the preparation and value assignment of gas standard of hydrogen sulfide in nitrogen. The range of the nominal amount-of-substance fractions of the comparison standard is 10 µmol/mol. A set of hydrogen sulfide in nitrogen gas mixtures were prepared by gravimetry and verified with gas chromatography-atomic emission detector (GC-AED) against a KRISS reference cylinder. The gravimetric values of the amount of substance fractions were adopted as key comparison reference values (KCRVs). The results of 9 participants are consistent with their KCRV. Therefore, it is possible for this key comparison to offer a good traceability and a harmonization among the global distribution data of H2S.
To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.
The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Nutation dynamics and multifrequency resonance in a many-body seesaw
Authors: Xu Hong-Ze , Zhang Shun-Yao , Lu Yu-Kai , Guo Guang-Can , Gong Ming 
Published: March 2021

Abstract
The multifrequency resonance has been widely explored in the context of single-particle models, of which the modulating Rabi model has been the most widely investigated. It has been found that with diagonal periodic modulation, steady dynamics can be realized in some well-defined discrete frequencies. These frequencies are independent of off-diagonal couplings. In this work, we generalize this physics to the many-body seesaw realized using the tilted Bose–Hubbard model. We find that the wave function will recover to its initial condition when the modulation frequency is commensurate with the initial energy level spacing between the ground and the first excited levels. The period is determined by the driving frequency and commensurate ratio. In this case, the wave function will be almost exclusively restricted to the lowest two instantaneous energy levels. By projecting the wave function to these two relevant states, the dynamics is exactly the same as that for the spin precession dynamics and nutation dynamics around an oscillating axis. We map out the corresponding phase diagram, and show that, in the low-frequency regime, the state is thermalized, and in the strong modulation limit, the dynamics is determined by the effective Floquet Hamiltonian. The measurement of these dynamics from the mean position and mean momentum in phase space are also discussed. Our results provide new insights into multifrequency resonance in the many-body system.
Excitation cross sections in a collision between two ground-state hydrogen atoms
Authors: Al Atawneh Saed J , Tőkési K 
Published: March 2021

Abstract
We present excitation cross sections in collision between two ground state hydrogen atoms using a four-body classical trajectory Monte Carlo model. Calculations were performed for impact energies in the range between 1.0 keV and 100 keV where the cross sections are highly relevant to the interest of the fusion research. Beside the total excitation cross sections for target and projectile we also present partial excitation cross sections into the 2s and 2p states of the target. The partial excitation cross sections are compared with the previously obtained theoretical and experimental results.
Novel cost-effective approach to produce nano-sized contact openings in an aluminum oxide passivation layer up to 30 nm thick for CIGS solar cells
Authors: Kandybka Iryna , Birant Gizem , de Wild Jessica , Buldu Dilara Gokcen , Kohl Thierry , Thiruvallur Eachambadi Ragha , Brammertz Guy , Manca Jean V , Meuris Marc , Poortmans Jef , Vermang Bart 
Published: March 2021

Abstract
This work presents a novel method of local contact openings formation in an aluminum oxide (Al2O3) rear surface passivation layer by the selenization of the lithium fluoride (LiF) salt on top of the Al2O3 for ultra-thin copper indium gallium (di)selenide (CIGS) solar cells (SCs). This study introduces the potentially cost-effective, fast, industrially viable, and environmentally friendly way to create the nano-sized contact openings with the homogeneous distribution in the thick, i.e. up to 30 nm, Al2O3 passivation layer. The passivation layer is deposited by atomic layer deposition, while the LiF layer is spin-coated. Selenization is done in the H2Se atmosphere and the optimal process parameters are deduced to obtain nano-sized and uniformly allocated openings as confirmed by scanning electron microscopy images. The contact openings were produced in the different thicknesses of the alumina layer from 6 nm to 30 nm. Furthermore, the Al2O3 rear surface passivation layer with the contact openings was implemented into ultra-thin CIGS SC design, and one trial set was produced. We demonstrated that the created openings facilitate the effective current collection through the dielectric Al2O3 layer up to 30 nm thick. However, the upper limit of Al2O3 thickness in which the contact openings can be created by the described method is not established yet. The produced passivated CIGS SCs show increased external quantum efficiency response due to the optical enhancement of the passivated cells. However, the production of SCs on the Al2O3 passivation layer with the openings created by selenization of LiF is not optimized yet.
Electronic and vibrational properties of the high T
c superconductor Bi2Sr2CaCu2O8: an ab initio study
Authors: Yelpo Carla , Faccio Ricardo , Ariosa Daniel , Favre Sofía 
Published: March 2021

Abstract
In this work, ab initio calculations were performed in order to study the vibrational spectra of the Bi2Sr2CaCu2O8 (Bi2212) compound. A structural modulation correction on some atomic positions, producing a distorted structure with lower symmetry, is used for the calculation. We argue that this correction allows to account for an average effect of the incommensurate superstructure, generating a more accurate representation of the real unit cell observed in this compound. A complete and conclusive vibrational assignment is performed, discussing the correspondences with previous experimental and theoretical reports. A brief analysis of the electronic density of states and band structure comparing the tetragonal and distorted unit cell is also included.
Electric control of nearly free electron states and ferromagnetism in the transition-metal dichalcogenides monolayers
Authors: Li Min , Du Er-Wei , Liang Yun-Ye , Shen Yu-Hao , Chen Ju , Ju Weiwei , An Yipeng , Gong Shi-Jing 
Published: March 2021

Abstract
Using the first-principles calculations, we explore the nearly free electron (NFE) states in the transition-metal dichalcogenides MX
2 (M = Mo, W; X = S, Se, Te) monolayers. It is found that both the external electric field and electron (not hole) injection can flexibly tune the energy levels of the NFE states, which can shift down to the Fermi level and result in novel transport properties. In addition, we find that the valley polarization can be induced by both electron and hole doping in MoTe2 monolayer due to the ferromagnetism induced by the charge injection, which, however, is not observed in other five kinds of MX
2 monolayers. We carefully check band structures of all the MX
2 monolayers, and find that the exchange splitting in the top of the valence band and the bottom of conduction band plays the key role in the ferromagnetism. Our researches enrich the electronic, spintronic, and valleytronic properties of MX
2 monolayers.
Monte Carlo-based dosimetric studies of a locally developed 170Tm LDR brachytherapy seed source
Authors: Sahoo Sridhar , Selvam T Palani , Pathan Munir , Saxena S K , Pandey Usha , Kumar Manoj , Kumar Yogendra 
Published: March 2021

Abstract

170Tm is being explored as a source for applications in brachytherapy. Although it has adequate physical properties, such as a short half-life (128.6 d), high specific activity and a mean photon energy of about 66 keV, it has a drawback of low photon yield (only about six photon emissions/100 beta emissions). The objective of this work is to study the dosimetric characteristics of a locally developed 170Tm brachytherapy seed source using the Monte Carlo-based EGSnrc code system. In this study, we calculate the dose rate constant, air-kerma strength, radial dose function, anisotropic function and 2D dose-rate distributions in water. Separate simulations are carried out by considering the photon (gamma and characteristic x-ray) and beta spectra of the source. For regions close to the source (surface of the source < r < 0.4 cm), the dose is solely due to direct dose deposition by beta particles. At larger distances (0.4 cm < r <10 cm), the dose is due to bremsstrahlung photons produced by beta particles and photon emissions. The calculated value of the dose rate constant is 1.217 ± 0.052 cGy h−1U−1. The value of S
k per mCi is 0.029 ± 0.0009 U mCi−1. The contributions of the inherent photon emission and the bremsstrahlung photons to the total S
k are 0.58 and 0.42, respectively.
Analyzing the effect of misalignment on single-filament carbon fiber tensile testing via stereoscopic computer vision imaging
Authors: Love-Baker Cole A , Harrell Timothy M , Brown Kenneth R , Bumgardner Clifton H , Li Xiaodong 
Published: March 2021

Abstract
An understanding of the constitutive properties of carbon fibers (CFs) is critical to the accuracy of high-resolution composite simulations and to the development of CF derived from low-cost alternative precursor materials. Single-fiber tensile testing is a capable tool to measure CF properties and is well suited to research efforts where only a small number of fibers may be available. However, single-fiber tensile tests are challenging to conduct due to the difficulty in handling small diameter fibers (5–15 μm), the brittleness of single fibers, and the required nanoscale/microscale resolution of testing equipment. The accuracy of the measured properties depends on several factors, but a critical factor is fiber misalignment, especially at short gauge lengths. Current standards do not address the effect of tensile specimen misalignment on measured properties. This work presents a robust method of fiber alignment using stereoscopic computer vision that enables users to align fibers vertically for tensile testing to improve the accuracy of resulting mechanical properties. Additionally, an analytical relationship between fiber misalignment angle and measured properties is developed and validated against the experimental results. As a result, new best practices for single-fiber tensile testing of CF are recommended.
Automatic extrinsic self-calibration of mobile LiDAR systems based on planar and spherical features
Authors: Yu Jiayong , Lu Xiushan , Tian Maoyi , Chan Ting On , Chen Chuanfa 
Published: March 2021

Abstract
Inaccurate extrinsic parameters are one of the major errors of a mobile LiDAR system (MLS). As different types of sensors with incommensurable precisions are integrated in an MLS, the extrinsic parameters cannot be easily isolated and estimated, especially in an automatic mode. To address this issue, this paper proposes an automatic extrinsic self-calibration method for an MLS based on planar and spherical features. First, the planar and spherical features are automatically extracted from scanned point cloud data of different strips using the Random Sample Consensus algorithm, and the corresponding features are matched after the extraction. Secondly, a rigorous relationship is established between the direct geo-referencing equation, the extrinsic parameters, and the geometric constraint model. Thirdly, the extrinsic parameters are calibrated by minimizing the sum of the squares of distances from points on the feature surface to the matched reference feature. Four datasets collected by using four types of MLS were used to verify the proposed method. As a result of combining two geometric features into a single self-calibration adjustment, the experimental results show that the proposed method is superior to the conventional plane-based method in terms of the positional accuracy. The standard deviation of the distance between the check features of the four datasets collected by several mobile platforms before (after) extrinsic calibration were 0.051 m (0.024 m), 0.060 m (0.018 m), 0.029 m (0.009 m), and 0.354 m (0.070 m), which demonstrated the high compatibility and practicality of the proposed method.
N-doped reduced graphene oxide-PEDOT nanocomposites for implementation of a flexible wideband antenna for wearable wireless communication applications
Authors: Thanh Tung Tran , Chen Shengjian Jammy , Fumeaux Christophe , Kim TaeYoung , Losic Dusan 
Published: March 2021

Abstract
We report a flexible and highly efficient wideband slot antenna based on a highly conductive composite of poly(3,4-ethylenedioxythiophene) (PEDOT) and N-doped reduced graphene oxide (N-doped rGO) for wearable applications. The high conductivity of this hybrid material with low sheet resistance of 0.56 Ω/square, substantial thickness of 55 μm, and excellent mechanical resilience (<5.5% resistance change after 1000 bending cycles) confirmed this composite to be a suitable antenna conductor. The antenna achieved an estimated conduction efficiency close to 80% over a bandwidth from 3 to 8 GHz. Moreover, the successful operation of a realized antenna prototype has been demonstrated in free space and as part of a wearable camera system. The read range of the system was measured to be 271.2 m, which is 23 m longer than that of the original monopole antennas provided by the supplier. The synergistic effects between the dual conjugated structures of N-doped rGO and PEDOT in a single composite with fine distribution and interfacial interactions are critical to the demonstrated material performance. The N-doped rGO sheet reinforces the mechanical stability whereas the PEDOT functions as additive and/or binder, leading to an improved electrical and mechanical performance compared to that of the graphene and PEDOT alone. This high-performing nanocomposite material meets requirements for antenna design and opens the door for diverse future non-metallic flexible electronic device developments.
The bifurcation set as a topological invariant for one-dimensional dynamics
Authors: Fuhrmann Gabriel , Gröger Maik , Passeggi Alejandro 
Published: March 2021

Abstract
For a continuous map on the unit interval or circle, we define the bifurcation set to be the collection of those interval holes whose surviving set is sensitive to arbitrarily small changes of (some of) their endpoints. By assuming a global perspective and focusing on the geometric and topological properties of this collection rather than the surviving sets of individual holes, we obtain a novel topological invariant for one-dimensional dynamics. We provide a detailed description of this invariant in the realm of transitive maps and observe that it carries fundamental dynamical information. In particular, for transitive non-minimal piecewise monotone maps, the bifurcation set encodes the topological entropy and strongly depends on the behavior of the critical points.
Traveling fronts in dissipative granular chains and nonlinear lattices
Authors: James Guillaume 
Published: March 2021

Abstract
We consider an infinite chain of particles with nonlinear elastic and dissipative nearest neighbors interactions. Assuming the existence of a traveling front between uniformly compressed (or stretched) states, we obtain jump conditions relating the wave speed and limiting particle velocities to the relative displacements at infinity. Using this result, we characterise compression fronts in chains of touching beads, for viscoelastic contact laws that include a nonlinear elastic force (generalised Hertz contact) and viscous dissipation. We compute compression fronts numerically for the generalised Kuwabara–Kono model in which the viscous contact force is proportional to the derivative of the elastic force, without precompression of the chain. Steady fronts are obtained both as the end result of the compression of one end of the chain and using a shooting method which provides numerically exact traveling waves. Depending on the magnitudes of contact damping and strain applied downstream, we obtain either overdamped (monotonic) or underdamped (oscillatory) compression fronts. To explain this transition and approximate the front profiles, we consider a continuum limit valid when the exponent of the contact nonlinearity is close to (and above) unity. Using multiscale expansions, we formally derive two different amplitude equations for long waves, a Burgers equation with logarithmic nonlinearity, and a logarithmic Korteweg–de Vries (KdV)–Burgers equation for small contact damping. Both models possess traveling front solutions that are in good agreement with the front profiles computed numerically in the granular chain. The analysis of the logarithmic KdV–Burgers equation allows one to approximate the critical damping corresponding to the transition from underdamped to overdamped fronts.