bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cost of Personal Protective Equipment During the First Wave of COVID-19
Authors: Mena Lora Alfredo , Ali Mirza , Spencer Sherrie , Takhsh Eden , Krill Candice , Bleasdale Susan 
Published: November 2021

Background: As the world prepared for and responded to the COVID-19 pandemic in early 2020, a rapid increase in demand for personal protective equipment (PPE) led to severe shortages worldwide. Acquisition of PPE in the general market was an integral part of pandemic response, along with the safeguarding of hospital supplies. We seek to quantify the difference in cost per unit (CPU) of PPE during the first wave of COVID-19 compared to prepandemic prices. Methods: We performed a retrospective review of market prices for PPE during the first surge of the pandemic in Chicago. Cost of PPE was tabulated and compared with prepandemic prices. The maximum cost per unit (CPU) of PPE was tabulated for each week, and the average cost throughout the pandemic was calculated. Disposable gowns, washable gowns, N95 respirators, face masks, and gloves were included in our analysis. Results: PPE prices were significantly higher during the pandemic compared to prepandemic prices (Figure 1). Disposable gown CPU peaked at $12 during the first week of March, 13.7 times higher than prepandemic prices, and the average gown CPU was 7.5 times higher than prepandemic prices. N95 respirators had a peak CPU of $12, and average CPU was 8 times higher than prepandemic prices. Face-mask CPU peaked at $0.55, 11 times higher, and averaged 9 times higher the regular price. Gloves averaged 2.5 times higher than the prepandemic CPU. Conclusions: Market prices for PPE were significantly elevated during the first weeks of the pandemic and remained high throughout the first wave of COVID-19. Multiple factors likely contributed to high prices, including demand shock, disrupted supply chains, and a rush to acquisition by healthcare systems and the general population alike. The impact of COVID-19 on prices highlights the importance of supply chains and national stockpiles for pandemic preparedness.Funding: NoDisclosures: None
COVID-19 Outbreak in a Hemodialysis Center Using Universal Masking and Eye Protection
Authors: Sifri Costi , Buckner Joan , Shelton Cady 
Published: November 2021

Background: Up to half of all new SARS-CoV-2 infections are acquired from presymptomatic or asymptomatic individuals. Hemodialysis patients and healthcare providers (HCPs) may be at increased risk for COVID-19 due to the need for extended close contact. Universal masking and eye protection are strategies used to reduce SARS-CoV-2 exposure, particularly from presymptomatic or asymptomatic individuals. We describe an outbreak of COVID-19 in an outpatient hemodialysis center despite universal masking and universal HCP eye protection. Methods: An COVID-19 outbreak investigation was performed in a hemodialysis center where universal masking was in use by all HCPs and patients and universal eye protection (goggles, safety glasses) was in use by all HCPs when directly encountering patients. After a cluster of cases was identified in early November 2020, all patients and HCPs were tested for SARS-CoV-2 by real-time reverse transcription polymerase chain reaction (RT-PCR) when symptomatic and weekly until the conclusion of the outbreak. Results: From November 12, 2020, through December 7, 2020, 14 (23.3%) of 60 patients and 9 (28.1%) of 32 HCPs tested positive for SARS-CoV-2 by RT-PCR (Figure 1). The median ages of the patients and HCPs were 64 years (range, 42–87) and 42 years (range, 29–68), respectively. Also, 5 (5.4%) individuals (3 patients and 2 HCPs) were asymptomatic at the time of testing. Furthermore, 7 (7.6%) individuals (5 patients and 2 HPCs) were hospitalized; 2 patients and no HCPs died. No lapses in universal masking or, for HCPs, eye protection prior to or during the outbreak were identified during the investigation. All HCPs and patients wore medical-grade face masks that were discarded at the end of the day; HCPs wore safety glasses or goggles during patient interactions. Although audits of face mask and eye protection compliance were not performed, independent interviews supported high HCP and patient adherence prior to the outbreak. Neither the staff nor patients shared meals at or outside the hemodialysis center. Most patients and HCPs shared the same hemodialysis shift, suggesting the presence of an index case; however, a source case could not be identified despite an extensive investigation. Conclusions: Universal masking and eye protection have been shown to reduce transmission of SARS-CoV-2 from presymptomatic or asymptomatic individuals in the healthcare setting. This report suggests that such measures cannot prevent all outbreaks. We speculate that certain factors associated with hemodialysis care, such as prolonged close patient–HCP contact, may have facilitated this outbreak. Whether nonadherence to universal masking and eye protection or failure of empiric droplet precautions contributed to this outbreak remains unknown.Funding: NoDisclosures: None
Whole-Genome Sequencing: The Key to Unlocking a Nosocomial Outbreak of Coronavirus Disease 2019 (COVID-19)
Authors: Gottlieb Lindsey , Sordillo Emilia , van Bakel Harm , Smith Barbara , Camins Bernard , Alsamarai Sarah , Simon Viviana , Kim Kilyoub 
Published: November 2021

Background: Accurately tracing nosocomial transmission of coronavirus disease 2019 (COVID-19) is critical to developing effective infection prevention policies. Given the high prevalence and variable incubation period of SARS-CoV-2 infection, the utility of traditional contact tracing is limited. We describe a nosocomial outbreak in which whole-genome sequencing (WGS) was pivotal to identifying the primary case. Methods: This study was conducted at a New York City academic hospital. The index case was identified on August 13, 2020, and the last case on September 9, 2020. Hospital policy required all inpatients to be screened for COVID-19 on admission by SARS-CoV-2 molecular amplification testing. All healthcare workers (HCWs) were required to wear masks and eye protection for patient care. After a patient (patient 1), who tested SARS-CoV-2 negative on admission, was positive on preprocedure screening on hospital day 9, contact tracing was initiated. Two patients (patients 2 and 3) and 13 HCWs with high-risk exposures (HREs) to patient 1 were quarantined and referred for testing. Additional surveillance testing was performed on 18 inpatients and 84 HCWs on the affected unit. Patients 2 and 3 and 3 HCWs (HCW-1, -2, and -3), only 1 of whom had a high-risk exposure to patient 1, tested positive. WGS was performed to further investigate this outbreak. Results: The outbreak variant (clade 20A) was found in samples from 6 patients and 2 HCWs. Patients 2 and 3 were roommates of patient 1 in the 2 days before patient 1’s positive test, and they did not consistently wear masks in the room. HCW-1 placed a peripheral IV in patient 1 the day before patient 1’s positive test without wearing eye protection. Four additional cases in this cluster (patients 4–6 and HCW-4) were identified by surveillance WGS of positive tests. A review indicated that patient 1 was located ~3 m (~10 feet) away from patient 4 in the emergency department (ED) for 6 hours on hospital day 1, when the admission SARS-CoV-2 test from patient 4 was not positive. No epidemiologic link was found to patient 5 or 6 or HCW-4. The specimen from HCW-2 was inadequate for WGS. The specimen from HCW-3 was not linked to this cluster. Conclusions: This complex nosocomial outbreak highlights the importance of WGS in understanding transmission events. Patient 4 was not identified by traditional contact tracing but was linked to patient 1 and was recognized as the primary case through WGS, having likely infected patient 1 in the ED. Based on these findings, we focused our corrective actions on more promptly isolating suspected COVID-19 cases in the ED, increasing inpatient masking, and improving HCW adherence to universal eye protection.Funding: NoDisclosures: None
Thinking Otherwise: Bringing Young People into Pediatric Concussion Clinical and Research Practice
Authors: Mah Katie , Gladstone Brenda , Cameron Deb , Reed Nick 
Published: November 2021

AbstractBackground:As rates of pediatric concussion have steadily risen, and concerns regarding its consequences have emerged, pediatric concussion has received increased attention in research and clinical spheres. Accordingly, there has been a commitment to determine how best to prevent and manage this injury that so commonly affects young people. Despite this increased attention, and proliferation of research, pediatric concussion as a concept has rarely, if ever, been taken up and questioned. That is, little attention has been directed toward understanding what concussion ‘is’, or how young people are regarded in relation to it. As a result, pediatric concussion is understood in decidedly narrow terms, constructed as such by a biomedical way of knowing.Aim:We aim to demonstrate how conceptualizing concussion, and young people, ‘otherwise’, enabled the co-production of a more nuanced and complex understanding of the experience of pediatric concussion from the perspective of young people.Approach:Drawing on an illustrative case example from a critical qualitative arts-based study, we demonstrate how bringing young people into research as ‘knowers’ enabled us to generate much-needed knowledge about concussion in young people.Implications:The critical thinking put forward in this paper suggests a different approach to pediatric concussion, which is shared in the form of implications for clinical and research practice.
From Nobility and Excellence to Generosity and Rights: Sophia's Defenses of Women (1739–40)
Authors: Broad Jacqueline 
Published: November 2021

AbstractThis article examines two early modern feminist works, Woman Not Inferior to Man (1739) and Woman's Superior Excellence Over Man (1740), written by “Sophia, A Person of Quality.” Scholars once dismissed these texts as plagiarisms or semi-translations of François Poulain de la Barre's De l’égalité des deux sexes (1673). More recently, however, Guyonne Leduc has drawn attention to the original aspects of these treatises by highlighting Sophia's significant variations on Poulain's vocabulary (Leduc 2010; 2012; 2015). In this article, I take Leduc's analysis a step further by demonstrating that Sophia's variations amount to unique and distinctive arguments for the restoration of women's rights, based on both the natural equality and the moral superiority of women compared to men. I argue that Sophia goes beyond Poulain's Cartesian insights to mount a critique of male tyranny characterized as a lack of generosity toward women. My contention is that Sophia's texts represent a culmination in a line of reasoning that extends from the querelle des femmes of the Renaissance to Poulain's Cartesian feminism of the seventeenth century, through to arguments for women's rights in the eighteenth century. Her works thus warrant greater recognition as significant turning points in the history of feminist thought.
Asymptotics of streamwise Reynolds stress in wall turbulence
Authors: Monkewitz Peter A. 
Published: November 2021

The scaling of different features of streamwise normal stress profiles$\langle uu\rangle ^+(y^+)$in turbulent wall-bounded flows is the subject of a long-running debate. Particular points of contention are the scaling of the ‘inner’ and ‘outer’ peaks of$\langle uu\rangle ^+$at$y^+\approxeq ~15$and$y^+ ={O}(10^3)$, respectively, their infinite Reynolds number limit, and the rate of logarithmic decay in the outer part of the flow. Inspired by the thought-provoking paper of Chen & Sreenivasan (J. Fluid Mech., vol. 908, 2021, p. R3), two terms of an inner asymptotic expansion of$\langle uu\rangle ^+$in the small parameter$Re_{\tau }^{-1/4}$are constructed from a set of direct numerical simulations (DNS) of channel flow. This inner expansion is for the first time matched through an overlap layer to an outer expansion, which not only fits the same set of channel DNS within 1.5 % of the peak stress, but also provides a good match of laboratory data in pipes and the near-wall part of boundary layers, up to the highest$Re_{\tau }$values of$10^5$. The salient features of the new composite expansion are first, an inner$\langle uu\rangle ^+$peak, which saturates at 11.3 and decreases as$Re_{\tau }^{-1/4}$. This inner peak is followed by a short ‘wall log law’ with a slope that becomes positive for$Re_{\tau }$beyond${O}(10^4)$, leading up to an outer peak, followed by the logarithmic overlap layer with a negative slope going continuously to zero for$Re_{\tau }\to \infty$.
Using local ecological knowledge to locate the western long-beaked echidna Zaglossus bruijnii on the Vogelkop Peninsula, West Papua, Indonesia
Authors: Pattiselanno Freddy , Iriansul  , Barnes Paul A. , Arobaya Agustina Y. S. 
Published: November 2021

AbstractThe Critically Endangered western long-beaked echidna Zaglossus bruijnii is believed to be distributed throughout the Vogelkop Peninsula in the Indonesian Province of West Papua, but there had formerly been no confirmed sightings of the species since the 1980s. We aimed to establish whether the species survives in this area. Fieldwork was carried out during January–April 2018 in Tambrauw Regency in the north and Teluk Bintuni Regency in the south. Fieldwork involved informal interviews with people, identified through chain referral sampling, who were knowledgeable about local animals and plants. Interviewees were asked about their knowledge of the western long-beaked echidna and if they had encountered them locally. Thirteen interviewees were familiar with the species and we were able to confirm informant records of one individual in Tambrauw Regency and three in Teluk Bintuni Regency. Measurements of the three individual echidnas in Teluk Bintuni Regency corroborated previous descriptions of the species. Interviewees described how echidnas are often seen in the forests around villages, especially during the wet season during January–April, when their foraging signs are easy to distinguish from those of other animals. These four records of the western long-beaked echidna are the first confirmed sightings since the 1980s. They suggest the species persists on the Vogelkop Peninsula, and anecdotal information from the interviewees suggests the species remains common. Nevertheless, detailed systematic surveys are required before any assertion about the status of this species can be made with confidence.
A proof-of-concept study applying machine learning methods to putative risk factors for eating disorders: results from the multi-centre European project on healthy eating
Authors: Krug I. , Linardon J. , Greenwood C. , Youssef G. , Treasure J. , Fernandez-Aranda F. , Karwautz A. , Wagner G. , Collier D. , Anderluh M. , Tchanturia K. , Ricca V. , Sorbi S. , Nacmias B. , Bellodi L. , Fuller-Tyszkiewicz M. 
Published: November 2021

AbstractBackgroundDespite a wide range of proposed risk factors and theoretical models, prediction of eating disorder (ED) onset remains poor. This study undertook the first comparison of two machine learning (ML) approaches [penalised logistic regression (LASSO), and prediction rule ensembles (PREs)] to conventional logistic regression (LR) models to enhance prediction of ED onset and differential ED diagnoses from a range of putative risk factors.MethodData were part of a European Project and comprised 1402 participants, 642 ED patients [52% with anorexia nervosa (AN) and 40% with bulimia nervosa (BN)] and 760 controls. The Cross-Cultural Risk Factor Questionnaire, which assesses retrospectively a range of sociocultural and psychological ED risk factors occurring before the age of 12 years (46 predictors in total), was used.ResultsAll three statistical approaches had satisfactory model accuracy, with an average area under the curve (AUC) of 86% for predicting ED onset and 70% for predicting ANv.BN. Predictive performance was greatest for the two regression methods (LR and LASSO), although the PRE technique relied on fewer predictors with comparable accuracy. The individual risk factors differed depending on the outcome classification (EDsv.non-EDs and ANv.BN).ConclusionsEven though the conventional LR performed comparably to the ML approaches in terms of predictive accuracy, the ML methods produced more parsimonious predictive models. ML approaches offer a viable way to modify screening practices for ED risk that balance accuracy against participant burden.
‘Why would I want sex now?’ A qualitative study on older women's affirmative narratives on sexual inactivity in later life
Authors: Gore-Gorszewska Gabriela 
Published: November 2021

AbstractThe existing research tries to understand the reasons for discontinuing sex in later life with the assumption that people want to be sexual. Although the growing body of literature informs that sex remains an integral part of older adults’ lives, a substantial number of older adults declare not being sexually active. This study aimed at exploring motives for deliberately choosing sexual inactivity among older women. Semi-structured interviews with 16 Polish women (aged 65–82) were thematically analysed in relation to the sexual scripts theory and the participants’ specific socio-cultural background. Three main themes regarding the reasons for cessation of their sex life were identified: ‘I am glad that sex does not concern me anymore’, ‘I am satisfied with my memories’ and ‘The right one’ or no one. The results indicate that some women give up sex for good, with no regrets or feeling of a loss; for others, it may be a temporary decision, its duration dependent on meeting the right partner. Developing sexual agency may encourage discontinuing their sex life – a choice perceived as optimal and liberating. Personal factors and the memories of marital relationships seem to shape older women's (a)sexual expectations. Acknowledging these nuances may contribute to a better understanding of older women's sexual functioning; implications for consideration in further research and practice are also discussed.
Karl Marx and the Global History of the Civil War: The Slave Movement, Working-Class Struggle, and the American State within the World Market
Authors: Battistini Matteo 
Published: November 2021

AbstractThis essay stitches together the fragments of Marx's work on the United States that are scattered in newspaper articles, letters, notes, in some digressions in his early writings, in his economic manuscripts and in Capital (1867). The main aim is to show that what we can call a “global history of the Civil War” emerges from his pen: a history that is global not simply in a geographical sense, that is, because it expands the European space beyond the Atlantic and towards the Pacific, but also because of the general meaning it takes on in the history of capitalism. The essay highlights how the Civil War opened the Marxian issue of emancipation, his vision of class struggle and his view of the working class, to the presence of a black proletariat that interacted with the struggle of the white working classes, the latter of which until then had been the main focus of his work. It also highlights how the different and disarticulated voices of labor – slave and free, black and white – on both sides of the Atlantic effected a revolutionary shift in the Civil War: interjecting a “revolutionary turn” into what we can call the “long constitutional history” of the political conflict between North and South that changed the economic and social shape of the nation. More importantly, the essay reconstructs what can be termed the “state moment,” which was entangled with the “long constitutional history” and the “revolutionary turn” of the Civil War. As the transnational calls for emancipation from slavery and wage labor impacted the transnational processes of accumulation of industrial capital, the American state became a player in the world market: its financial and fiscal policies became socially linked to the government of industrial capital. In this sense, as the essay underlines in the conclusion, the “global history of the Civil War” that Marx effectively drafted, outlined the theoretical and political hypothesis that formed the basis of his mature reflection in the pages of Capital: the “emancipation of labour” should be thought of as a global issue, “neither a local nor a national, but a social problem.”
Human Extinction and Moral Worthwhileness
Authors: Finneron-Burns Elizabeth 
Published: November 2021

AbstractIn this article I make two main critiques of Kaczmarek and Beard's article ‘Human Extinction and Our Obligations to the Past’. First, I argue that there is an ambiguity in what it means to realise the benefits of a sacrifice and that this ambiguity affects the persuasiveness of the authors’ arguments and responses to various objections to their view. Second, I argue that their core argument against human extinction depends on an unsupported assumption about the existence and importance of existential benefits.
Respectability and race between the suburb and the city: an argument about the making of ‘inner-city’ London
Authors: Waters Rob 
Published: November 2021

AbstractThis article concentrates on the development of an inner-city imaginary, and a linked suburban imaginary, in the era of post-war reconstruction and post-colonial migration. It argues that these two historical processes – reconstruction and migration – need to be seen as interlinked phenomena, which bound the histories of race and class together. First, it proposes that understanding how the inner city developed and was lived as a structure of feeling requires attending to its meaning both among those who peopled its often-nebulous borders, and among those who escaped it but nonetheless measured their escape by it. Second, it proposes that understanding the popular force of inner city and suburb as imaginative spaces means recognizing how they became crucial landscapes in a revived culture of respectability, which in the second half of the twentieth century became a racialized culture. This was the other migration that defined what the inner city meant.
Neurodevelopmental Outcomes in Preterm Children with Sickle Cell Disease
Authors: Bills Sarah E. , Schatz Jeffrey , Hunt Erin , Varanasi Sreya , Johnston Julia , Bradshaw Jessica 
Published: November 2021

ABSTRACTObjectives:To explore the combined effect of pediatric sickle cell disease (SCD) and preterm birth on cognitive functioning.Methods:Cognitive functioning was examined in children ages 6–8 with high risk SCD genotypes born preterm (n = 20) and full-term (n = 59) and lower risk SCD genotypes/no SCD born preterm (n = 11) and full-term (n = 99) using tests previously shown to be sensitive to SCD-related neurocognitive deficits. Factorial ANOVAs and log linear analyses were conducted to examine the relationship between SCD risk, preterm birth status, and cognitive outcomes. Continuous scores were examined for specific tests. Children were categorized as having an abnormal screening outcome if at least one cognitive score was ≥1.5 standard deviations below the population mean.Results:Children with elevated risk due to high risk SCD and preterm birth performed worse than other groups on a test of expressive language but not on tests that emphasize processing speed and working memory. There was a three-way interaction between preterm status, SCD risk, and abnormal screening outcome, which was largely driven by the increased likelihood of abnormal cognitive scores for children with high risk SCD born preterm.Conclusions:The combination of SCD and preterm birth may confer increased risk for language deficits and elevated rates of abnormal cognitive screenings. This suggests that neurodevelopmental risk imparted by comorbid SCD and preterm birth may manifest as heterogenous, rather than specific, patterns of cognitive deficits. Future studies are needed to clarify the domains of cognitive functioning most susceptible to disease-related effects of comorbid SCD and preterm birth.