bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alternaria chrysanthemi
. [Descriptions of Fungi and Bacteria].
Authors: UK, CAB International  , Ellis M. B. 
Published: August 2021

Abstract

A description is provided for
Alternaria chrysanthemi
. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: On
Chrysanthemum
spp. DISEASE: On stems, leaves, flowers and seeds of
Chrysanthemum maximum
; also one record from India on
C. indicum
. On the leaves spots are round, at first pale grey, and up to 1 cm diam. ; later grey or brownish black, often with a whitish spot in the centre surrounded by pale and dark concentric rings. GEOGRAPHICAL DISTRIBUTION: Austria, India, Netherlands, U. S. A. TRANSMISSION: The pathogen has been repeatedly isolated from seeds.
Periconia macrospinosa
. [Descriptions of Fungi and Bacteria].
Authors: UK, CAB International  , Ellis M. B. 
Published: August 2021

Abstract

A description is provided for
Periconia macrospinosa
. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS:
Sorghum
spp. ; also from wheat, roots of
Chenopopodium album
and red clover, rhizospheres of sugarcane, wheat and
Rauwolfia serpentina
and from soil. DISEASE: This species, which has been confused with
P. circinata
the causal organism of milo disease of sorghum, was shown to be non-pathogenic by Lefebvre, Johnson & Sherwin (1949). GEOGRAPHICAL DISTRIBUTION: Australia, Canada, England, France, Hong Kong, India, U.S.A. TRANSMISSION: Soil-borne.
Eremothecium ashbyi
. [Descriptions of Fungi and Bacteria].
Authors: UK, CAB International  , Mukerji K. G. 
Published: August 2021

Abstract

A description is provided for
Eremothecium ashbyi
. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: On
Gossypium hirsutum
and also on other species of
Gossypium
. DISEASE: Stigmatomycosis or cotton boll rot and staining of the lint. The lint becomes discoloured and the seed coat is stained brown in spots (30: 124). GEOGRAPHICAL DISTRIBUTION: Sudan, South Africa and U.S.A. (Tarr, 1955). TRANSMISSION: Mechanical transmission by hemipterous insects.
Sphaerotheca macularis
. [Descriptions of Fungi and Bacteria].
Authors: UK, CAB International  , Mukerji K. G. 
Published: August 2021

Abstract

A description is provided for
Sphaerotheca macularis
. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: On
Humulus lupulus
and many other plants, e.g.
Fragaria vesca
, especially in the
Rosaceae
(Junell, 1967; Blumer, 1967; Dennis, 1960). The fungus usually occurs in the conidial state on leaves and stems, sometimes also on sepals and fruits. DISEASE: Hop and strawberry mildew. Mostly infecting nursery plants. GEOGRAPHICAL DISTRIBUTION: World wide on
Fragaria
spp. and
Humulus
spp. TRANSMISSION: New infection in spring (usually May) comes from dormant mycelium in the leaves (41: 161; 45: 1443).
Sugarcane streak virus
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Sugarcane streak virus
Storey. Hosts: Sugarcane (Saccharum). Information is given on the geographical distribution in AFRICA, Dahomey, Egypt, Ivory Coast, Kenya, Malawi, Mozambique, Portugal (Madeira), Réunion, Rhodesia, South Africa, Uganda.
Physoderma maydis
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Physoderma maydis
(Miyabe) Miyabe. Hosts: Maize (
Zea mays
). Information is given on the geographical distribution in AFRICA, Cameroon (W.), Ghana, Kenya, Libya, Malawi, Mozambique, Nigeria (W.), Rhodesia, Sierra Leone, Tanzania Zaire (Congo), Zambia, ASIA, Bangladesh, Cambodia, China (general), India, Indonesia, Japan, Laos, Nepal, Pakistan, Philippines, Thailand, USSR (Republic of Georgia), AUSTRALASIA & OCEANIA, Australia, NORTH AMERICA, Mexico, USA (general with host), CENTRAL AMERICA & WEST INDIES, Costa Rica, Cuba, Guatemala, Panama, Salvador, SOUTH AMERICA, Argentina, Brazil (Sao Paulo), Colombia, Venezuela.
Gloeosporium limetticola
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Gloeosporium limetticola
Clausen. Hosts: Lime (Citrus aurantifolia). Information is given on the geographical distribution in AFRICA, Kenya, Morocco, Mozambique, Senegal, Tanzania, Zaire, ASIA, India (Andaman Islands, Assam, Uttar Pradesh), Indonesia, Syria, AUSTRALASIA & OCEANIA, Fiji, Hawaii, New Zealand, EUROPE, Yugoslavia, NORTH AMERICA, Bermuda, Mexico, USA (California, fla), CENTRAL AMERICA & WEST INDIES, Barbados, Costa Rica, Cuba, Dominica, Grenada, Guatemala, Haiti, Honduras (USDA), Jamaica, Montserrat, Panama (USDA), Puerto Rico, St. Lucia, St. Vincent, Trinidad & Tobago, SOUTH AMERICA, Argentina (Tucuman), Brazil, Colombia, Guyana, Surinam, Venezuela.
Pezicula malicorticis
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Pezicula malicorticis
(Jacks.). Nannf. Hosts: Apple (Malus pumila), Pear (Pyrus communis), Quince (Cydonia oblonga). Information is given on the geographical distribution in AFRICA, Rhodesia, AUSTRALASIA & OCEANIA, Australia (Western Australia), New Zealand, EUROPE, Britain & Northern Ireland, Denmark, Finland, France, West Germany, Irish Republic, Netherlands, Norway, Poland, Sweden, Switzerland, USSR (Estonia), NORTH AMERICA, Canada (British Columbia), USA.
Pseudomonas savastanoi
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Pseudomonas savastanoi
(E.F. Smith) Stevens. Hosts: Olive (Olea europea) and Oleander (Nerium oleander). Information is given on the geographical distribution in AFRICA, Algeria, Libya, Morocco, South Africa, Tanzania, Tunisia, ASIA, Iran, Iraq, Israel, Lebanon, Turkey, USSR (Republic of Georgia), AUSTRALASIA & OCEANIA, Australia, New Zealand, EUROPE, Cyprus, Czechoslovakia, France, Greece (Crete), Italy (incl. Sicily), Netherlands, Poland, on Forsythia, Portugal, Spain, Sweden, Switzerland, USSR, Yugoslavia, NORTH AMERICA, Mexico, USA, SOUTH AMERICA, Argentina, Brazil (Rio Grande do Sul), Colombia, Peru, Uruguay.
Agrobacterium rhizogenes
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Agrobacterium rhizogenes
(Riker et al.) Connecticut Hosts: Apple (
Malus pumila
), Rose (
Rosa
) etc. Information is given on the geographical distribution in ASIA, Japan, AUSTRALASIA & OCEANIA, Australia (Western Australia), (Victoria), EUROPE, Bulgaria, France (S), NORTH AMERICA, USA (California, Connecticut, Central States, New Engl. States, Idaho, New York, Maryland, DC, Pennsylvania, Tex.).
Sclerotinia squamosa
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Sclerotinia squamosa
(Vienn. Bourg.) Dennis. Hosts: Onion (Allium cepa). Information is given on the geographical distribution in AFRICA, Mauritius, ASIA, Hong Kong, Japan, Korea, AUSTRALASIA & OCEANIA, Australia, New Zealand, EUROPE, Belgium, Britain, Bulgaria, France (Brittany), Italy, Netherlands, Poland, NORTH AMERICA, Canada (Ontario, Que), USA, SOUTH AMERICA, Brazil (Rio Grande do Sul).
Xanthomonas campestris pv. carotae
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Xanthomonas campestris pv. carotae
(Kendrick) Dye. Hosts: Carrot (
Daucus carota L. var. sativa DC
.). Information is given on the geographical distribution in AFRICA, South Africa, ASIA, USSR, AUSTRALASIA & OCEANIA, Australia (New South Wales), EUROPE, Hungary, Italy (Sicily), Poland, USSR (Voronezh), NORTH AMERICA, Canada, USA (California, Idaho, Iowa, Ore).
Xanthomonas populi
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Xanthomonas populi
(Ridé) M. Ridé & S. Ridé. Hosts: Poplar (Populus spp.). Information is given on the geographical distribution in EUROPE, Belgium, Britain, Czechoslovakia, France, Germany, Hungary, Netherlands, Poland, Romania, USSR.
Wheat streak mosaic virus
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Wheat streak mosaic virus
McKinney. Hosts: Wheat (
Triticum
), Maize (
Zea mays
) and other Gramineae. Information is given on the geographical distribution in ASIA, Jordan, Turkey, USSR (C. Asia; N. Kazakhastan), EUROPE, Romania, Yugoslavia, USSR (Krasnodar, Moldavia, Rostov, Ukraine), NORTH AMERICA, Canada (Alberta Ontario), USA (Western areas and Great Plains).
Cronartium comandrae
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Cronartium comandrae
Peck. Hosts: Hard pines (
Pinus spp
.) and Comandra spp. Information is given on the geographical distribution in NORTH AMERICA, Canada - Alberta, British Columbia, Manitoba, New Brunswick, Northwest Territory, Ontario, Quebec, Saskatchewan, Yukon, Territory, USA, Alabama, Arkansas, Arizona, California, Colorado, Connecticut, Delaware, Idaho, Illinois, Indiana, Iowa, Kentucky, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Mexico, New Jersey, New York, North Dakota, Ohio, Oregon, Pennsylvania, South Dakota, Texas, Tennessee, Utah, Vermont, Washington, Wisconsin, Wyoming.
Physopella zeae
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Physopella zeae
(Mains) Cummins & Ramachar. Hosts: Maize (
Zea mays
). Information is given on the geographical distribution in CENTRAL AMERICA & WEST INDIES, Central America (general), Costa Rica, Cuba, Dominican Republic, Grenada, Guatemala, Honduras, Jamaica, Mexico, Nicaragua, Panama, Puerto Rico, Salvador, St. Vincent, Trinidad, SOUTH AMERICA, Colombia,? Ecuador, Peru, Venezuela.
Fusarium oxysporum f.sp. elaeidis
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Fusarium oxysporum f.sp. elaeidis
Toovey. Hosts: Oil palm (Elaeis guineensis). Information is given on the geographical distribution in AFRICA, Cameroon, Congo, Nigeria, SOUTH AMERICA, Colombia.
Coleosporium ipomoeae
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Coleosporium ipomoeae
(Schw.) Burrill. Hosts: Hard pines (Pinus spp.) and sweet potato (Ipomoea batatas). Information is given on the geographical distribution in AFRICA, Malawi, South Africa (Natal), Tanzania, Uganda, ASIA, Indonesia (Java), NORTH AMERICA, Bermuda, USA (New Jersey to Florida, Arizona, Illinois, Kansas, Mississippi, Oklahoma, Texas), CENTRAL AMERICA & WEST INDIES, Belize, Dominican Republic, Grenada, Jamaica, Mexico, Puerto Rico, St Vincent, Trinidad, SOUTH AMERICA, Bolivia, Brazil (Sao Paulo), Colombia, Peru, Venezuela.
Cercospora elaeidis
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Cercospora elaeidis
Steyaert. Hosts: Oil palm (Elaeis guineensis). Information is given on the geographical distribution in AFRICA, Angola, Cameroon, Congo Republic, Dahomey, Ghana, Guinea, Ivory Coast, Nigeria, Portuguese Guinea, Rhodesia, Sao Tomé, Senegal, Sierra Leone, Sudan, Tanzania, Zaire Republic (Congo).
Rhizina undulata
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Rhizina undulata
Fr. Hosts: Coniferae. Information is given on the geographical distribution in AFRICA, Rhodesia, South Africa, Swaziland, EUROPE, Belgium, Britain, Bulgaria, Finland, France, Germany, Ireland, Netherlands, Poland, Sweden, USSR (Lativa, Lithuania), NORTH AMERICA, Canada (British Columbia), USA.
Aecidium mori
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Aecidium mori
Barclay. Hosts: mulberry (Morus spp.), Broussonetia spp. Information is given on the geographical distribution in ASIA, Afghanistan, Burma, China, Nanjing (Nanking), Zhejtang (Chekiang), Jiangsu (Kiangsu), Yunnan, Sichuan (Szechwan), India, Indonesia, Japan, Korea, Pakistan, Philippines, Taiwan, Thailand.
Sorosporium saponariae
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Sorosporium saponariae
Rudolphi. Hosts: Saponaria officinalis, Dianthus spp. and other Caryophyllaceae. Information is given on the geographical distribution in AFRICA, Algeria, Morocco, ASIA, Pakistan, USSR, AUSTRALASIA, Australia, EUROPE, Austria, Bulgaria, Czechoslovakia, Denmark, Finland, France, German, Democratic, Republic, Germany, Hungary, Italy, Norway, Poland, Romania, Spain, Sweden, Switzerland, USSR, Yugoslavia, NORTH AMERICA, USA, New York, Colorado, Utah, Nevada, Connecticut, Nevada. SOUTH AMERICA, Argentina, Chile.
Lachnellula willkommii
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Lachnellula willkommii
(Hartig) Dennis. Hosts: larch (Larix spp. ; also Pseudolarix). Information is given on the geographical distribution in ASIA, China, northeast, Japan, EUROPE, Belgium, Czechoslovakia, Denmark, Eire, Finland, France, Germany, Hungary, Italy, Netherlands, Norway, Portugal, Romania, Sweden, UK, England, England & Wales, Scotland, USSR, Minsk, Estonia, Byelorussia, Leningrad, Yugoslavia, NORTH AMERICA, Canada, NB, Nova Scotia, USA, MA.
Stagonospora meliloti
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Stagonospora meliloti
(Lasch) Petrak. Hosts: Medicago, Melilotus and Trifolium species. Information is given on the geographical distribution in ASIA, Iran, Japan, Korea, Turkey, AUSTRALASIA & OCEANIA, Australia, New South Wales, Queensland, SA, Vic., WA, Tas, New Zealand, Norfolk Island, EUROPE, Bulgaria, Czechoslovakia, Denmark, France, Germany, Greece, Hungary, Italy, Norway, Poland, Portugal, Romania, Sweden, Switzerland, UK, England, Scotland, USSR, Estonia, Lithuania, Yugoslavia, NORTH AMERICA, Canada, Manitoba, Ontario, Saskatchewan, USA, SOUTH AMERICA, Brazil, Chile, Colombia.
Embellisia allii
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Embellisia allii
(Campanile) E.G.Simmons. Hosts: White garlic (Allium sativum). Information is given on the geographical distribution in AFRICA, Egypt, Morocco, Zimbabwe, ASIA, Israel, Peninsular Malaysia, Malaysia, Singapore, AUSTRALASIA & OCEANIA, Australia, New Zealand, EUROPE, Austria, Bulgaria, Greece, Italy, Romania, Spain, UK, Britain, England, Yugoslavia, NORTH AMERICA, Mexico, USA, CENTRAL AMERICA & WEST INDIES, Puerto Rico, SOUTH AMERICA, Argentina, Brazil, Chile, Venezuela.
Nimbya gomphrenae
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Nimbya gomphrenae
(Togashi) E.G. Simmons syn. Alternaria gomphrenae Togashi. Hosts: Gomphrena globosa. Information is given on the geographical distribution in ASIA, Burma, Hong Kong, India, Indonesia, Java, Japan, Kampuchea, Peninsular Malaysia, Malaysia, Nepal, Sri Lanka, Thailand, AUSTRALASIA & OCEANIA, Australia, Queensland, NORTH AMERICA, USA, CENTRAL AMERICA & WEST INDIES, Cuba, Jamaica, Panama, Trinidad.
Phyllachora lespedezae
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Phyllachora lespedezae
(Schwein.) Sacc. Hosts: Lespedeza spp., also Desmodium and Kummerowia. Information is given on the geographical distribution in NORTH AMERICA, Canada, USA.
Phyllachora machaeriicola
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Phyllachora machaeriicola
(P. Henn.) Theiss. & H. Sydow. Hosts: Machaerium spp. Information is given on the geographical distribution in CENTRAL AMERICA & WEST INDIES, Trinidad, SOUTH AMERICA, Bolivia, Brazil, Colombia, Peru, Venezuela.
Phomopsis asparagi
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Phomopsis asparagi
(Sacc.) Bubák. Hosts: Asparagus officinalis, A. plumosus, A. verticillatus. Information is given on the geographical distribution in AFRICA, Ethiopia, ASIA, China, India, Bihar, Karnataka, MP, Uttar Pradesh, Indonesia, Java, Japan, Korea, Malaysia, Sabah, Pakistan, Russia, Siberia, Taiwan, Thailand, EUROPE, Denmark, France, Germany, Italy, Portugal, Spain, Yugoslavia, NORTH AMERICA, Bermuda, USA, CENTRAL AMERICA & WEST INDIES, Puerto Rico, SOUTH AMERICA, Brazil.
Pseudococcus comstocki
. [Distribution map].
Authors: UK, CAB International  
Published: August 2021

Abstract

A new distribution map is provided for
Pseudococcus comstocki
(Kuwana) Hemiptera: Coccoidea, Pseudococcidae (Comstock's mealybug, white peach scale). Attacks apple, pear, mulberry, cherry, peach, litchi, coffee, pomegranate. Information is given on the geographical distribution in USSR, Armenian SSR, Azerbaijan SSR, Georgian SSR, Kirghiz SSR, Moldavian SSR, Russian SSR, Tadzhik SSR, Turkmen SSR, Ukrainian SSR, uzbek SSR, Africa, St. Helena, Asia, Cambodia, China, Hong Kong, Japan, Korea, Malaysia, Thailand, Tibet, North America, Canada, British Columbia, Ontario, USA, California, Connecticut, Delaware, Georgia, Indiana, Louisiana, Maryland, New Jersey, New York, Ohio, Pennsylvania, South Carolina, Virginia, West Virginia.
Entrustable professional activities for pharmacy students: A primer for solid organ transplant preceptors
Authors: Lichvar Alicia , Chandran Mary Moss , Do Vincent , Rendulic TrisAnn , Szczepanik Amanda , Pierce Dana , Park Jeong M 
Published: August 2021

AbstractPurposeThe role of a solid organ transplant pharmacist is multifaceted and translates to diverse experiential and elective learning experiences that can be provided to pharmacy learners. Here we provide a guide to integrating pharmacy students into patient care and other pharmacist activities in solid organ transplantation.SummaryThoughtful incorporation of learners into clinical practice and clinical research creates a positive learning environment for pharmacy students that can foster the development of core skills necessary for students to become “practice-ready” and “team-ready” pharmacy graduates and can equip them with valuable skills to incorporate into the specialty practice areas and careers they pursue. To help develop educational experiences, attention to the list of core entrustable professional activities (EPAs) established by the American Association of Colleges of Pharmacy can help create a rich environment of learning with carefully cultivated tasks. Furthermore, learners can serve as transplant pharmacist extenders to assist in overall patient care and multidisciplinary involvement on the transplant team. This article serves as a “how-to” guide for applying the EPA framework to integrating pharmacy students in patient care and other pharmacist activities in solid organ transplantation and other specialty practice areas.ConclusionAs pharmacy preceptors design and operationalize their teaching to incorporate EPAs, they can benefit from recommendations tailored to specialty practice areas such as solid organ transplantation. Students may start and finish these experiences at different EPA levels, but continuance of training will allow them to achieve the final EPA level across the 6 EPA domains.
Defending the Kratzerian presuppositional error theory
Authors: Salinger Elliot 
Published: August 2021

AbstractThis paper provides a new solution to the problem of moral permissions for the moral error theory. The problem is that the error theorist seems committed to the claim that all actions are morally permitted, as well as to the contradictory claim that no action is morally permitted. My solution understands the moral error theory as the view that folk moral discourse is systematically in error by virtue of suffering from semantic presupposition failure, which I show is consistent with a Kratzerian semantics for deontic modals in natural language. Formally, the solution is to treat the ordering source parameter within Kratzer’s semantics as undefined in the case of folk moral discourse. The paper concludes with thoughts about the import of the solution proffered for the alleged independence of the moral error theory from normative ethics.
A Prospective, Multicenter, Single-Blind, Randomized, Controlled Study of VYC-15L, a Hyaluronic Acid Filler, in Adults for Correction of Infraorbital Hollowing
Authors: Fabi Sabrina , Zoumalan Christopher , Fagien Steve , Yoelin Steve , Sartor Marta , Chawla Smita 
Published: August 2021

Abstract

Background
Rejuvenation of the under-eye area is a popular facial aesthetic treatment option.

Objectives
This study evaluated the safety and effectiveness of VYC-15L for the correction of moderate or severe infraorbital hollowing.

Methods
This was a randomized, controlled, single-blind study with a primary endpoint defined as the proportion of participants with ≥1-grade improvement at Month 3 assessed by an evaluating investigator employing the Allergan Infraorbital Hollow Scale. Three-dimensional imaging was conducted to assess infraorbital volume up to Month 12. Procedure pain and injection-site responses (ISRs) were documented, and safety was monitored throughout the study.

Results
At Month 3, the difference between treatment (83.1%) and control (15.6%) was 67.5% (95% CI = 52.9 to 82.0, P &lt; 0.0001). 3D imaging showed a mean volume increase from baseline of 0.733 mL (left) and 0.777 mL (right) at Month 12. Mean pain scores were ≤1.7 (scale of 0 to 10). Most ISRs with initial treatment were mild/moderate and resolved in ≤1 week, including tenderness (49.5%), bruising (42.7%), and swelling (41.7%). Thirty-four participants had treatment-emergent adverse events (TEAEs), of which 14 (10.3%) had treatment-related TEAEs, including bruising (3.8%) and swelling/edema (2.9%), which resolved in ≤2 weeks. Three participants had swelling/edema starting &gt;30 days posttreatment; 2 resolved in ≤4 days, 1 by 45 days. No treatment-related serious AEs were reported.

Conclusions
VYC-15L was safe and effective for the correction of moderate or severe infraorbital hollowing and lasted through 1 year.

Level of Evidence: 2
A comparison of deep learning-based pre-processing and clustering approaches for single-cell RNA sequencing data
Authors: Wang Jiacheng , Zou Quan , Lin Chen 
Published: August 2021

Abstract
The emergence of single cell RNA sequencing has facilitated the studied of genomes, transcriptomes and proteomes. As available single-cell RNA-seq datasets are released continuously, one of the major challenges facing traditional RNA analysis tools is the high-dimensional, high-sparsity, high-noise and large-scale characteristics of single-cell RNA-seq data. Deep learning technologies match the characteristics of single-cell RNA-seq data perfectly and offer unprecedented promise. Here, we give a systematic review for most popular single-cell RNA-seq analysis methods and tools based on deep learning models, involving the procedures of data preprocessing (quality control, normalization, data correction, dimensionality reduction and data visualization) and clustering task for downstream analysis. We further evaluate the deep model-based analysis methods of data correction and clustering quantitatively on 11 gold standard datasets. Moreover, we discuss the data preferences of these methods and their limitations, and give some suggestions and guidance for users to select appropriate methods and tools.