Investigating the intention to receive the COVID-19 vaccination in Macao: implications for vaccination strategies
Authors: Ung Carolina Oi Lam , Hu Yuanjia , Hu Hao , Bian Ying 
Published: June 2021

AbstractImportanceUnderstanding the intention of receiving COVID-19 vaccines is important for informing effective vaccination strategies especially for areas with low incidence.ObjectiveThis study aimed to investigate the intention to receive COVID-19 vaccination, identify the key influencing factors, and determine the most important intention predictors using a theoretically principled model.Design, setting, and participantsThis was a cross-sectional online survey study hosted by Survey Monkey and implemented for 10 days from May 14 2021. People who aged 18 years or above and had been residing in Macao for 12 months prior to the study were recruited through social media.Main outcomes and measuresIntention, the constructs of protection motivation theory (perceived severity, perceived susceptibility, maladaptive response reward, self-efficacy, response-efficacy, and response cost), constructs of health belief model (cues to action), social attitude, social norm, past experience and information seeking behavior, in addition to demographic variables.ResultsOf the 552 respondents, 79.5% aged between 25 and 54 years old, 59.4% were female, and 88% had a bachelor degree or above. Overall, 62.3% of the respondents indicated their intention while 19.2% were hesitant and 18.5% did not have any intention. While 67.0% believed COVID-19 infection was life-threatening, only 19.0% thought they were at risk. Control variables such as age, gender, education level, and having travel plans were significantly correlated with intention. Significant associations were found between intention and all the measures (p<0.05). The most important positive predictors of intention were “being able to make arrangement to receive the vaccine” (β = 0.333, P <0.001), “a sense of social responsibility” (β = 0.326, P < 0.001), and “time off from work after vaccination” (β = 0.169, P <0.001), whereas “concerns over vaccine safety” (β = - 0.124, P < 0.001) and “relying on online resources for vaccine information” (β = -0.065, P <0.05) were negative predictors. Perceived severity was not a predictor of intention.Conclusion and relevanceMulti-component strategies that address various factors affecting intention are needed to formulate effective interventions. Health literacy, vaccination convenience, social responsibility, reasonable incentives and well-informed risk and benefit analysis are recommended consideration for future vaccination campaigns.Key PointsQuestionWhat is the intention to receive COVID-19 vaccination in Macao and the influencing factors?FindingsA cross-sectional study involving 552 respondents found that the intention rate of COVID-19 vaccination was 62.3% in Macao. Positive predictors of intention included being able to make arrangement to receive the vaccine, a sense of social responsibility, and an offer of time off from work after vaccination. Concerns over vaccine safety and relying on online resources for vaccine information were negative predictors.MeaningIntention to receive COVID-19 vaccination is multifactorial requiring multi-component strategies to promote vaccine uptake.