bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of «hunger hormone» in the regulation of eating behavior in patients with Parkinson’s disease
Authors: Tarianyk K. A. 
Published: July 2021

Objective — to evaluate the correlation between ghrelin levels, body mass index and the course of the disease in patients with Parkinson’s disease
Methods and subjects. We examined 40 patients with Parkinson’s disease and 20 patients without signs of neurodegenerative disease (control group), who were examined and admitted to the neurological department. Patients were distributed into groups: 1 group — 20 patients with a disease duration of 12.1 ± 2.3 years, group 2 — 20 patients with a disease duration of 7.3 ± 1.6 years, group 3 — control, 20 patients without signs of morbidity. The diagnosis was made according to the criteria of the World Brain Bank of Great Britain. The severity of the disease was determined by the Hen and Yar scale. All patients, after signing the consent agreement, underwent a general clinical, neurological examination with assessment of anthropometric parameters: height, weight, body mass index. Also, patients underwent laboratory determination of serum ghrelin levels using the method of enzyme‑linked immunosorbent assay (ELISA) on the basis of the Research Institute of Genetic, Immunological Basis of Pathology and Pharmacogenetics of the Ukrainian Medical Dental Academy.
Results. Studies indicate that in the group of patients with a longer course of the disease (group 1) there was an increase in BMI, which can be interpreted as obesity or overweight, compared with group 2 and control, where the rate was normal. In group 2, where the duration of the disease was shorter, there was a decrease in BMI, accompanied by weight loss of patients. In each group of examined patients there were patients with different forms of the disease, but in the second group patients with akinetic‑rigid form of the disease prevailed, so these patients in neurological status suffered more from stiffness, immobility. Normally, ghrelin level rises in the morning during hunger and decreases after eating. A similar picture was observed in the control group of patients, where the rate of morning ghrelin was elevated. When assessing fasting plasma ghrelin levels in groups of patients, there is a slight decrease in the indicator compared with the control group.
Conclusions. There is a clear correlation between the duration of the disease, body mass index and hunger hormone levels in patients with Parkinson’s disease. In patients with the initial stages of the disease there is a decrease in body mass index, which is a prognostically unfavorable sign. Fluctuations in ghrelin levels may be associated with decreased energy intake due to gastrointestinal dysfunction, increased energy expenditure caused by motor manifestations of the disease, or increased glucose metabolism with the use of drugs and changes in the eating behavior of patients.
La cochinilla corticícola Matsucoccus feytaudi Ducasse, 1941 y su papel en el decaimiento de Pinus pinaster Aiton en el Parque Natural de la Sierra de Baza (Granada, Andalucía, España)
Authors: Guzmán Álvarez José Ramón , Gómez de Dios M.A. , Muñoz Risueño A. , Alguacil Picón F. , Gómez Milán F. , Nebot Sanz B. , Cobos Aguirre J.F.J. , Carrasco Gotarredona A. , Rodríguez Reviriego S. , Sánchez Callado F.M. , Redondo Noval J.A. , Ruiz J.M. , Sánchez Anguita A. 
Published: July 2021

En 2016 se produjo un episodio de decaimiento de gran intensidad sobre los pinares de repoblación del Parque Natural de la Sierra de Baza. Los primeros indicios de este proceso de mortalidad masivo se habían observado ya en 2014 y 2015 en Sierra de Baza y Sierra de los Filabres (Granada y Almería), así como en la cara norte de Sierra Nevada, también en las dos provincias.
Asociado a este proceso se observó la presencia notable de la cochinilla Matsucoccus feytaudi Ducasse, 1941. Con objeto de dilucidar el papel que este insecto estaba desempeñando en la muerte del arbolado, en febrero de 2017 se colocaron 12 trampas de feromonas desarrolladas por el INRA (Francia) en la Sierra de Baza y 8 trampas adicionales en otras zonas de Andalucía, tanto en rodales procedentes de repoblación como con dinámica natural, con o sin manifestación de síntomas patentes de decaimiento: Sierra de Almijara (Albuñuelas, Granada); Sierra Nevada (Abla, Almería; Jerez del Marquesado, Granada); Sierra de los Filabres (Alcóntar, Almería), Sierra de Baza (Valle del Zalabí, Granada); Sierra Morena (Aldeaquemada, Jaén); Los Reales de Sierra Bermeja (Estepona, Málaga); y el Espacio Natural de Doñana (Almonte, Huelva).
Se presentan los resultados derivados del trampeo llevado a cabo durante los meses de febrero a mayo de 2017, los cuales muestran una presencia muy extendida de M. feytaudi en la mayor parte de las localizaciones, discutiéndose el rol de este insecto en el episodio de decaimiento. Los resultados sugieren que el factor desencadenante del episodio de decamiento haya sido principalmente de tipo climático, actuando este insecto como un factor asociado que acelera la muerte del arbolado.
Glioma-related epilepsy in patients with diffuse high-grade glioma after the 2016 WHO update: seizure characteristics, risk factors, and clinical outcomes
Authors: Li Lianwang , Fang Shengyu , Li Guanzhang , Zhang Kenan , Huang Ruoyu , Wang Yinyan , Zhang Chuanbao , Li Yiming , Zhang Wei , Zhang Zhong , Jin Qiang , Zhou Dabiao , Fan Xing , Jiang Tao 
Published: July 2021

OBJECTIVE
The aim of this study was to investigate the epidemiological characteristics, associated risk factors, and prognostic value of glioma-related epilepsy in patients with diffuse high-grade gliomas (DHGGs) that were diagnosed after the 2016 updated WHO classification was released.

METHODS
Data from 449 patients with DHGGs were retrospectively collected. Definitive diagnosis was reaffirmed according to the 2016 WHO classification. Seizure outcome was assessed using the Engel classification at 12 months after surgery. Univariate and multivariate analyses were performed to identify risk factors associated with preoperative and postoperative glioma-related epilepsy. Lastly, the prognostic value of glioma-related epilepsy was evaluated by Kaplan-Meier and Cox analysis.

RESULTS
The incidence of glioma-related epilepsy decreased gradually as the malignancy of the tumor increased. Age < 45 years (OR 2.601, p < 0.001), normal neurological function (OR 3.024, p < 0.001), and lower WHO grade (OR 2.028, p = 0.010) were independently associated with preoperative glioma-related epilepsy, while preoperative glioma-related epilepsy (OR 7.554, p < 0.001), temporal lobe involvement (OR 1.954, p = 0.033), non–gross-total resection (OR 2.286, p = 0.012), and lower WHO grade (OR 2.130, p = 0.021) were identified as independent predictors of poor seizure outcome. Furthermore, postoperative glioma-related epilepsy, rather than preoperative glioma-related epilepsy, was demonstrated as an independent prognostic factor for overall survival (OR 0.610, p = 0.010).

CONCLUSIONS
The updated WHO classification seems conducive to reveal the distribution of glioma-related epilepsy in DHGG patients. For DHGG patients with high-risk predictors of poor seizure control, timely antiepileptic interventions could be beneficial. Moreover, glioma-related epilepsy (especially postoperative glioma-related epilepsy) is associated with favorable overall survival.
Master’s Art Photo Project “Ukrainian Renaissance”. Part 1: “Ukrainian Girl with a Pearl Earring. In the Footsteps of Jan Vermeer”
Authors: Gavran Iryna , Kotliar Svitlana , Zaspa Iryna 
Published: July 2021

The author’s message for this Master’s photo art project consisted of creating a photographic work inspired by the Renaissance and Ukrainian traditions, folklore. A harmonious combination of the Renaissance heritage with the Ukrainian historical and cultural heritage, the disclosure of the concept of “renaissance” in two contexts. The Renaissance heritage is studied as world history and art era. The Ukrainian historical and cultural heritage analysis aims at reviving Ukrainian authenticity and its learning and implementation in a modern interpretation. Since the project’s author is fond of modelling and has participated in the organisation of different shootings for more than five years, and is also the Bachelor of Fine Arts in Art and Visual Culture, it was decided to create a photo art project, where she would be a model and ideological organiser and draw parallels with the help of Fine Art. In this project, the Renaissance features are reflected through associative connections with famous paintings of artists in a new Ukrainian interpretation. The second concept of “renaissance” has the meaning of reviving Ukrainian values, customs, traditions through the symbolic image of a Ukrainian girl who appears in the photos of a photo art project in various roles.
The series of works consists of portrait images of a girl following the theme of the project. In total, there are five series in the project.
Determination of crack resistance of a tank with elliptical crack
Authors: Pyskunov Serhii , Shkryl Oleksii , Maksymiuk Yurii 
Published: July 2021

The occurrence of crack-like defects is a common phenomenon in the operation of vertical steel tanks (VST). Such defects can occur both at the beginning of the operation of the tanks, which may be associated with a violation of the manufacture conditions or the installation procedures of the tank elements and during operation. Over time, such defects increase significantly and turn into cracks. Existing regulations prohibit the operation of VST with cracks. At the same time, the organization that operates the tank does not always have the opportunity to perform repairs immediately. There are cases of trouble-free operation of tanks with non-through surface cracks at the stage of sustainable growth, which are confirmed by model calculations are known from practical experience. The analysis of crack resistance of the VST-5000 tank with a semi-elliptical crack under the action of hydrostatic pressure is carried out in the work. The level of filling the tank with petroleum products is 95% of its height. The semi-elliptical crack is located on outside surface of the wall panel in lower row of cladding. Determination of crack resistance of a tank with a crack is performed on the basis of stress intensity factors (SIF). Direct and energy methods were used to SIF calculation. Determination of the stress-strain state is performed on the basis of the semi-analytical finite element method (SFEM). The SIF distribution along the crack front obtained using SFEM by both direct and energy methods almost coincides and agrees well with the values of SIF calculated by the direct method when using three-dimensional FEM. The obtained values of SIF differ along the crack front by 50%: the minimum value of SIF acquires at the point of the front, which is located on the outer surface of the tank, the maximum one - at the point of the front inside the wall that is furthest from the outer surface. The obtained results show the quite uneven SIF distribution along the crack front, so that the calculation of such problems requires the spatial setting of problem.
Application of a free radical scavenger edaravone in patients with hemorrhagic stroke
Authors: Halushko O.A. 
Published: July 2021

BACKGROUND. The free radical scavenger edaravone helps to reduce the area of ischemic injury and improve the longterm effects of stroke, and is therefore widely used in the treatment of ischemic stroke. However, the role of edaravone in the treatment of hemorrhagic stroke patients has not yet been clarified.
OBJECTIVE. To investigate the feasibility and effectiveness of the use of the free radical scavenger edaravone in the treatment of patients with acute hemorrhagic stroke.
MATERIALS AND METHODS. A search was conducted for studies and systematic reviews for the keywords “acute stroke”, “intracerebral hemorrhage”, “subarachnoid hemorrhage”, “hemorrhagic transformation”, “edaravone” in the Google Scholar database published between 2003 and 2020.
RESULTS. The use of edaravone in patients with intracerebral hemorrhage was accompanied by activation of anti-inflammatory and reduction of pro-inflammatory peptides, activation of anti-apoptotic mechanisms, reduction of lipid peroxidation and oxidative trauma, reduction of permeability of the hematocenosis.
CONCLUSIONS. The main effects of edaravone have been to reduce neurological deficits, accelerate the rate of recovery of neurological disorders, and improve functional outcomes. Thus, the introduction of edaravone in patients with hemorrhagic stroke has proven to be reliably effective and safe.
Cutaneous Manifestations of Hypothyroidism A Prospective Hospital based clinical study in Bangladesh
Authors: Kumar Saha Bijoy , Shahin Md Mahabubur Rahaman , Siddique Md Rahmat Ullah 
Published: July 2021

Normal functioning thyroid is much more important for healthy skin. The association thyroid disorders with cutaneous manifestations is complex. Various studies have revealed multitude of cutaneous changes (in skin, hair and nails) that occur in thyroid hormonal dysfunction, in both hyper and hypothyroid states. The present study was designed to ascertain the varied cutaneous manifestations of hypothyroidism. This is a case control hospital based clinical study conducted in the Department of Dermatology and Venereology, BSMMU, over a period of one year, from May 2010 to May 2011. Fifty diagnosed cases of hypothyroidism constituted the subject material for the study and additional 50 Euthyroid persons were taken as control who were evaluated for the presence of any cutaneous manifestation. There are 50 patients of hypothyroidism among which 6 male & 44 female. The most common cutaneous feature in patients with hypothyroidism was coarse, rough, dry skin followed by pallor of skin, with carotenemia in 52.75% of the patients, nail changes in 38.9% of the patients, diffuse hair loss in 33.3% of the patients, palmoplantar keratoderma in 33.3% of the patients, and loss of lateral third of the eyebrows in 22.2% of the patients. Myxedematous facies were seen in 12% of the hypothyroid patients in our study. The relation between hypothyroidism and skin have profound clinical importance in dermatological practice.
CBMJ 2017 January: Vol. 06 No. 01 P: 24-27
Comparative study between ondansetron vs Palonosetron for controlling postoperative nausea and vomiting
Authors: Hasan Muhammad Masud , Islam Md Shafiqul , Ara Anjuman , Fazilatunnesa - , Rahman Md Ashiqur , Sultana Mst Habiba , Akhtar Sabiha 
Published: July 2021

Postoperative nausea and vomiting (PONV) is a major complication in patients who undergo surgery under general anaesthesia. Various drug regimens and antiemetic interventions have been tried from time to time for prevention of PONV but with a variable success rate. The aim of the study is to compare between ondansetron vs Palonocstron for controlling postoperative nausea and vomiting. In this prospective study, 100 patients aged 18-60 years of ASA GRADE-I and II scheduled for undergoing surgery under general anaesthesia after taking informed written consent at a tertiary care hospital, were randomly divided into two groups of 50 each. Group-A was given palonosetron 75 μg and Group-B was given ondansetron 4 mg. At 72 hours, nausea and vomiting were statistically significant between ondansetron and palonosetron groups. Postoperative side-effects such as headache, dizziness and drowsiness were not statistically significant between ondansetron and palonosetron groups. In conclusion, the antiemetic efficacy of palonosetron is similar to that of Ondansetron for preventing PONV during the first 24 hours after patients who undergo surgery under general anaesthesia. But after 72 hours, nausea and vomiting were statistically higher in ondansetron group than palonosetron group.
CBMJ 2017 July: Vol. 06 No. 02 P: 15-20
Somatic chromosome number and ploidy level in three Curcuma spp. from Bangladesh
Authors: Bonna Ishrat Jahan , Akter Suma , Sultana Syeda Sharmeen 
Published: July 2021

Three Curcuma L. species were investigated cytogenetically which represent diversed staining pattern of heterochromatins in interphase nuclei and prophase chromosomes with orcein staining. Curcuma longa and C. caesia were found to possess 2n = 3x = 63 somatic chromosomes whereas 2n = 2x = 42 chromosome number in C. zedoaria is reported for the first time from Bangladesh. Total chromosome length recorded in C. longa, C. caesia and C. zedoaria were 145.08 ± 2.85 μm, 164.93 ± 4.29 μm and 97.78 ± 2.41 μm, respectively. This was the first attempt to measure the length of the chromosomes for these species. The experiment confirmed the basic chromosome number x = 21 with triploid (C. longa, C. caesia) and diploid (C. zedoaria) Curcuma plants. Polyploidy could be employed in the evolution and diversification of the genus Curcuma, which is an essential factor to characterize the species of this genus.
Dhaka Univ. J. Biol. Sci. 30(2): 133-140, 2021 (July)
Soil fertility and leaf nutrient status of litchi orchard sites
Authors: Zannat Tasnim , Meem Farhana Firoz , Promi Rubaiat Sharmin , Poppy Umme Qulsum , Rahman MK 
Published: July 2021

Twelve soil and twelve leaf samples were collected from twelve litchi (Litchi chinensis Sonn.) orchards from different locations of Dinajpur to evaluate some physico-chemical properties and nutrient status of soil, and concentration of nutrients in litchi leaf. The pH of the soil varied from very strong acidic to medium acidic (4.8 - 5.7), organic matter content varied from 0.84 - 1.88%, EC varied from 302.4 - 310.2 μS/cm. The dominant soil textural class was clay loam. The average particle density was 2.49g/cm3. Total N, P, K and S in soils were 0.053 - 0.180%, 0.02 - 0.07%, 0.046 - 0.370 meq/100 g, and 0.015 - 0.028%, respectively. Available N, P, K, S, Zn, Fe, Mn and B in soils 30.40 - 57.8 mg/kg, 10.53 - 14.33 mg/kg, 0.03 - 0.32 meq/100 g, 20.03-34.80 mg/kg, 0.68-1.50 μg/g, 31.8 - 41.5 μg/g, 6.75 - 7.39 μg/g and 0.25-0.51 μg/g, respectively. The concentration of total N, P, K, S, Zn and Mn in the leaf were 1.74 - 2.20%, 0.11 - 0.188%, 0.104- 0.198%, 0.129 - 0.430%, 12 - 14 μg/g and 30 - 74 μg/g, respectively. The overall results indicated that the fertility status of the soils under the litchi plantation in the Dinajpur area are medium fertile. So, farmers could be advised to grow litchi plants after applying amendments to the soils to improve the physico-chemical properties in the Dinajpur area of Bangladesh.
Dhaka Univ. J. Biol. Sci. 30(2): 141-149, 2021 (July)
Growth and yield performance of strawberry (Fragaria ananassa) under various doses of vermicompost and NPK fertilizers grown at rooftop of Charfasson area in the southern parts of Bangladesh
Authors: Rahman Moomtahina , Alauddin Md , Ali AHM Zulfiquar 
Published: July 2021

A pot experiment was carried out on the rooftop of a building at Charfasson town Bhola to evaluate the growth and yield performance of strawberry (Fragaria ananassa) as influenced by different doses of vermicompost and inorganic fertilizers in the winter season of 2020-2021. Each pot was filled with ten kg soil and arranged in a completely randomized design having seven treatments with three replications. Treatments were T1: Control (-VC), T2: 5 t VC/ha, T3: 10 t VC/ha, T4: 15 t VC/ha, T5: 20 t VC/ha, T6: 25 t VC/ha, and T7: 50% RDF NPK (40 - 15-25 kg/ha). Different agronomic parameters were measured at the intervals of 30, 60, 90, and 120 days after sowing of seeds. All the treatments of vermicompost showed better responses in agronomic parameters than the control treatment. Among them, T5 treatment tends to show significantly (p<0.05) higher plant height (18.5 cm), number of the leaf (54/plant), root length (15.50 cm), first flowering (at 61 days), fruit length (5.75 cm), fruit diameter (13.75 cm), number of fruits (15/plant), the average weight of fruit (14.50 g), the fresh yield of fruits (13.59 t/ha), fresh weight of root (10.41 g/plant), fresh weight of reproductive structure (3.12 g/plant), weight of the dry reproductive structure (3.12 g/plant) and benefit-cost ratio (9.37). T6 treatment showed significantly (p<0.05) higher leaf area (49.00 cm2), fresh weight of petiole (4,61 g/plant), the weight of dry root (2.20 g/plant), weight of dry leaf (5.87 g/plant), weight of dry petiole (1.42 g/plant) and weight of dry biomass (12.48 g/plant). T2, T3 and T4 treatments showed significantly (p<0.05) higher growth than T7 treatment. The overall findings revealed that the application of vermicompost (20 t/ha) in the strawberry plant might be a suitable method in rooftop gardening to achieve its better agronomic and yield parameters in the southern parts of Bangladesh.
Dhaka Univ. J. Biol. Sci. 30(2): 283-292, 2021 (July)
Clay mineralogy of soils from lower atrai basin of Bangladesh
Authors: Islam ABMS , Khan ZH , Mazumder AR , Moslehuddin AZM , Uddin MM , Mori Y 
Published: July 2021

The lower Atrai basin, the study area, lies in the Agroecological Zone-5 (AEZ-5) of Bangladesh. This study reveals the clay mineral composition of top soils of seven different soil series viz. Binsara, Taras, Jaonia, Hasnabad, Laskara, Manda and Mainam developed in the basin. X-ray diffraction (XRD) technique was employed to identify and quantify the minerals. Results show that mica (41 to 59%) was the most dominant mineral among all soils except Laskara. In Laskara soils, the interstratified mica-vermiculite-smectite (41%) was the predominant mineral. Next to mica, kaolinite (10 to 12%) was found to be present in the Binsara, Taras 1, Jaonia, and Taras 2 soils. Chlorite (7 to 17%) was identified in all the soils and was found to be the second dominant mineral in the Manda and Mainam soils. In contrast, the interstratified mica-vermiculitesmectite (33%) was found to be the second dominant mineral in the Hasnabad soils. Small amounts of vermiculite mineral (1 to 13%) were identified in almost all the soils except Binsara. All the soils have interstratified mica-chlorite minerals (2 to 7%). A tiny amount of smectite (1%) was identified in Taras 1 soil. As far as the clay mineralogical composition is concerned, most studied soils were found at the initial stage of weathering, indicating the high potential to sustain low input subsistence agriculture.
Dhaka Univ. J. Biol. Sci. 30(2): 293-306, 2021 (July)
Reivindicación de la ley y exigencias consecuentes para el legislador de nuestro tiempo
Authors: Astarloa Huarte-Mendicoa Ignacio 
Published: July 2021

El artículo examina las características que deben cumplir las leyes, de acuerdo con la Constitución, respetando los principios de generalidad y abstracción, la no arbitrariedad del legislador, los principios de buena regulación, y las garantías de la seguridad jurídica frente a las leyes de preceptos intrusos y las ómnibus, el abuso de las urgencias y los procedimientos especiales, las frecuentes leyes modificativas o las complejas especialidades que requiere la legislación en ámbitos técnicos o científicos. En lugar de recrearnos en la literatura de la crisis de la ley se propone elaborar las leyes con rigor, haciendo realidad el respeto a esos principios y tras la reflexión y el debate plural debidos. Ello implica a todos los poderes, pero, muy especialmente, al Poder Legislativo porque si el Parlamento no asume la responsabilidad para que la ley pueda consolidarse como el gran instrumento de la convivencia que debe ser en este siglo XXI, nadie lo sustituirá en esta tarea. Para ello, se considera indispensable la modificación integral del procedimiento legislativo mediante la reforma en profundidad de los Reglamentos Parlamentarios. En lo orgánico, potenciando el decisivo papel de las Mesas de las Cámaras, auxiliadas por los letrados, las Secretarías Generales en su conjunto y una novedosa Oficina de la Calidad Legislativa, e introduciendo la figura del Coordinador de cada proyecto de ley, que vigile su coherencia y calidad durante toda la tramitación [...]