bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of the Hydrological Behavior of Watersheds in the Context of Climate Change (Northwestern Algeria)
Authors: Belarbi Halima , Touaibia Bénina , Boumechra Nadir , Abdelbaki Chérifa , Amiar Sakina 
Published: October 2021

AbstractThe aim of this work is to study the temporal evolution of the rainfall-runoff relations of four basins in northwestern Algeria: the Tafna Maritime, Isser Sikkak, downstream Mouilah and Upper Tafna basins. The adopted approach consists of analyzing hydroclimatic variables using statistical methods and testing the nonstationarity of the rainfall-runoff relation by the cross-simulation method using the GR2M model. The results of the different statistical methods applied to the series of rainfall and hydrometric variables show a decrease due to a break in stationarity detected since the mid-1970s and the beginning of the 1980s. The annual rainfall deficits reached average values of 34.6% during the period of 1941–2006 and 29.1% during the period of 1970–2010. The average annual wadi flows showed average deficits of 61.1% between 1912 and 2000 and 53.1% between 1973 and 2009. The GR2M conceptual model simulated the observed hydrographs in an acceptable manner by providing calculated runoff values in the calibration and validation periods greater or less than the observed runoff values. The application of the cross-simulation method highlighted the nonstationarity of the rainfall-runoff relations in three of the four studied basins, indicating downward trends of monthly runoff.
Post-cold War Ethiopian Land Policy and State Power in Land Commercialisation
Authors: Soboka Teshome Emana 
Published: October 2021

AbstractLand policy is one of the issues that affects the lives of millions of people in Ethiopia. The main purpose of this chapter is to explore how the policy has become instrumental for state land commercialisation after the 1991 regime change when the guerrilla fighter group—the Ethiopian People’s Revolutionary Democratic Front (EPRDF)—took power by overthrowing the military dictatorial government. Based on the data gathered from various sources, the chapter argues that the government has implemented different land policies, all of which were used to strengthen state power over land ownership. This state land monopolisation assisted the government to commercialise land by developing state-sponsored institutions that have been catalysing the process of land transaction in favour of large-scale commercial farming. At the beginning of its coming to power, the EPRDF-led government promised to overhaul the land policy of the country with the objective to ensure fair access to land for the citizens. In the meantime, however, all the legal frameworks were directed towards the strengthening of state power over land. This state domination over land ownership brought about several unintended outcomes, such as corruption and unfair access to the land, which, in turn, resulted in mistrust between the state and society.
Operative treatment of fragility fractures of the pelvis: a critical analysis of 140 patients
Authors: Rommens Pol Maria , Hofmann Alexander , Kraemer Sven , Kisilak Miha , Boudissa Mehdi , Wagner Daniel 
Published: October 2021

AbstractBackgroundFragility fractures of the pelvis (FFP) are a clinical entity with an increasing frequency. Indications for and type of surgical treatment are still a matter of debate.PurposeThis retrospective study presents and critically analyses the results of operative treatment of 140 patients with FFP.SettingLevel-I trauma center.Materials and methodsDemographic data, comorbidities, FFP-classification, type of surgical stabilization (percutaneous (P-group) versus open procedure (O-group)), length of hospital stay (LoS), general in-hospital complications, surgery-related complications, living environment before admission, mobility and destination at discharge were retracted from the medical and radiographic records. Patients were asked participating in a survey by telephone call about their quality of life. SF-8 Physical Component Score (PCS) and SF-8 Mental Component Score (MCS) were calculated as well as the Parker Mobility Score (PMS) and the Numeric Rating Scale (NRS).ResultsMean age was 77.4 years and 89.3% of patients were female. 92.1% presented with one comorbidity, 49.3% with two or more comorbidities. Median length of hospital stay was 18 days, postoperative length of hospital stay was 12 days. 99 patients (70.7%) received a percutaneous operative procedure, 41 (29.3%) an open. Patients of the O-group had a significantly longer LoS than patients of the P-group (p = 0.009). There was no in-hospital mortality. There were significantly more surgery-related complications in the O-group (43.9%) than in the P-group (19.2%) (p = 0.006). Patients of the O-group needed more often surgical revisions (29.3%) than patients of the P-group (13.1%) (p = 0.02). Whereas 85.4% of all patients lived at home before admission, only 28.6% returned home at discharge (p < 0.001). The loss of mobility at discharge was not influenced by the FFP-classes (p = 0.47) or type of treatment (p = 0.13). One-year mortality was 9.7%. Mortality was not influenced by the FFP-classes (p = 0.428) or type of treatment (p = 0.831). Median follow-up was 40 months. SF-8 PCS and SF-8 MCS were moderate (32.43 resp. 54.42). PMS was 5 and NRS 4. Follow-up scores were not influenced by FFP-classes or type of treatment.ConclusionPatients with FFP, who were treated operatively, suffered from a high rate of non-lethal general, in-hospital complications. Open surgical procedures induced more surgery-related complications and surgical revisions. Mental and physical follow-up scores are low to moderate. Condition at follow-up is not influenced by FFP-classes or type of treatment. Indications for operative treatment of FFP must be critically examined. Surgical fixation should obtain adequate stability, yet be as less invasive as possible. The advantages and limitations of different surgical techniques have to be critically evaluated in prospective studies.
Partial intracapsular tonsillectomy in the treatment of pediatric obstructive sleep apnea/hypopnea syndrome: a prospective study with 5-year follow-up
Authors: Cavaliere Matteo , De Luca Pietro , De Bonis Egidio , Maurizi Riccardo , Cassandro Claudia , Ralli Massimo , Cassandro Ettore , Scarpa Alfonso 
Published: October 2021

Abstract
Objective
To assess efficacy and safety of tonsil reduction with bipolar forceps electrocautery as treatment of paediatric obstructive sleep apnea/hypopnea syndrome (OSAHS).

Study design
Prospective interventional study.

Methods
Two hundred and sixty-three children aged 4–10 years with OSAHS and an apnea hypopnea index (AHI) > 3 were enrolled from March 2013 to January 2016. Pre-operative evaluation included oropharyngeal clinical examination with fiberoptic nasopharyngoscopy, OSA-18 questionnaire and overnight sleep study. All children were treated with adenoidectomy and tonsillotomy with bipolar forceps. OSA-18 questionnaire and overnight sleep study were performed 30 days after surgery.

Results
Pre-operative average of the OSA-18 questionnaires was of 70.3 (SD = 9.7); 30-day post-operative score was 23.15 (SD = 8.2; p = 0.045). Pre-operative average Apnea Hypopnea Index (AHI) score was 9.41 (SD = 4.1); 30-day post-operative average of AHI score was of 1.75 (SD = 0.8; p = 0.012). Oxygen Desaturation Index (ODI) rate changed from 7.39 (SD = 4) to 1.34 (30-day post-operative) (SD = 4.7; p = 0.085). NADIR rate changed from 79% (SD = 6.32) to 90% (30-day post-operative) (SD = 5.18; p = 0.00012). Peri- and post-operative complications in our sample were mainly pain (average 75 doses of paracetamol), while bleeding did not occur (0%). All patients received a follow-up examination 5 years after surgery to evaluate tonsil size; at this time-point, a reduction in tonsil size from 3.6 (3–4; SD = 4.2) to 1.3 (1–2; SD = 5.5) was found, while tonsil regrowth was observed in five children (2%).

Conclusion
This study showed that partial tonsillotomy with bipolar forceps electrocautery associated to adenoidectomy is an effective technique in treating OSAHS symptoms in children and ensures less complications in terms of hemorrhage, postoperative pain and infections compared to traditional adenotonsillectomy. The very low tonsillar regrowth rate reported in this study may support the routine use of this technique.
Long-term clinical outcome and satisfaction survey in patients with neurotrophic keratopathy after treatment with cenegermin eye drops or amniotic membrane transplantation
Authors: Sacchetti Marta , Komaiha Chiara , Bruscolini Alice , Albanese Giuseppe Maria , Marenco Marco , Colabelli Gisoldi Rossella Anna Maria , Pocobelli Augusto , Lambiase Alessandro 
Published: October 2021

Abstract

Purpose
Neurotrophic keratopathy (NK) is a degenerative corneal disease caused by damage of trigeminal innervation. The purpose of this study is to evaluate the clinical outcomes and patient-reported satisfaction of treatment with amniotic membrane transplantation (AMT) or cenegermin eye drops in patients with NK.

Methods
Clinical charts of patients with NK treated with AMT (group A) or cenegermin eye drops (group B), with at least 12 months of follow-up, were reviewed for demographics, medical history, corneal healing, and disease recurrence. Patient satisfaction was evaluated by a newly developed questionnaire investigating patient’s appreciation of treatment of NK (2 items) and satisfaction with NK treatment outcomes (5 items).

Results
At the end of treatment, complete corneal healing was observed in 13/15 (86%) patients in group A and in 23/24 (96%) in group B. At 12 months follow-up, 6/13 patients (46%) in group A and 3/23 patients (13%) in group B showed recurrence of NK (p = 0.037).
Survival analysis showed that group B remained recurrence free for a significantly longer period of time than the group A (p = 0.028). Patients in group B showed a significantly higher satisfaction when compared with patients in group A (total score: 65.7 ± 15.7 vs 47.4 ± 12.8, p = 0.003), both in terms of patients’ appreciation of treatment (78.3 ± 15.9 vs 52.2 ± 30, p = 0.020) and satisfaction with treatment outcomes (60.7 ± 21 vs 45.4 ± 13.3, p = 0.037).

Conclusions
Treatment of NK with cenegermin was associated with long-term maintenance of corneal integrity and a higher degree of patient satisfaction.
Clinical outcome of bonded partial indirect posterior restorations on vital and non-vital teeth: a systematic review and meta-analysis
Authors: Dioguardi Mario , Alovisi Mario , Troiano Giuseppe , Caponio Carlo Vito Alberto , Baldi Andrea , Rocca Giovanni Tommaso , Comba Allegra , Lo Muzio Lorenzo , Scotti Nicola 
Published: October 2021

Abstract
Objectives
The survival rate of indirect partial adhesive restorations on vital versus endodontically treated teeth is still controversial. The hypothesis is that there may be a difference in the survival rate of partial adhesive restorations performed on non-vital teeth compared to vital teeth.

Materials and methods
This systematic review was conducted following the PRISMA guidelines. The considered clinical studies investigated the outcomes of adhesive inlays, onlays, and overlays conducted over the past 40 years, focusing on Kaplan–Meier survival curves to calculate the hazard ratio (primary objective) and the survival rate (secondary objective) between vital and non-vital teeth. The risk of bias was assessed using the Newcastle–Ottawa Scale. Studies included in the review were identified through bibliographic research on electronic databases (“PubMed,” “Scopus,” “Cochrane Central Register of Controlled Trial,” and “Embase”). The K agreement between the two screening reviewers was evaluated.

Results
A total of 55,793 records were identified on PubMed, Scopus, and other bibliographic sources, and after the application of the eligibility and inclusion criteria, eight articles were included for qualitative analysis and six for quantitative analysis. The meta-analysis of the primary and secondary outcomes demonstrated that hazard ratios (HR = 8.41, 95% CI: [4.50, 15.72]) and survival rates (OR = 3.24, 95% CI: [1.76, 5.82]) seemed more favorable for indirect partial adhesive restorations on vital teeth than for those on endodontically treated teeth.

Conclusions
Within the limits of this study, these findings suggest that the risk of failure of indirect partial adhesive restorations on endodontically treated teeth is higher than on vital teeth.

Clinical relevance
The use of partial adhesive restorations on vital and endodontically treated teeth showed different long-term clinical outcomes.
Formation of lithiated gold and its use for the preparation of reference electrodes — an EQCM study
Authors: Behling Christopher , Mayrhofer Karl J. J. , Berkes Balázs B. 
Published: October 2021

AbstractLithiated gold wires can be used to build reference electrodes with outstanding potential stabilities over several days and even over the course of one year. These electrodes are well suited for investigations in the context of lithium-ion batteries (LIBs). In this work, a detailed procedure for the preparation of such electrodes with tailored mechanical properties, which can be fitted gastight into electrochemical cells using commercially available fittings, is given. The electrochemical lithiation process is studied using the electrochemical quartz crystal microbalance (EQCM) technique, and the differences in lithiation of wire type and thin film type gold electrodes are discussed. All experiments were carried out with two different electrolytes, namely, a LiPF6 and a lithium bis(trifluoromethane sulfonyl) imide (LiTFSI)-based electrolyte, and we conclude that for a higher lithiation rate and long-term stability, the use of LiTFSI-based electrolyte in the preparation phase is beneficial. The EQCM data provides a better insight in the analysis of film formation processes, like the buildup of the solid electrolyte interphase (SEI) during the lithiation, the rate of deposition of metallic lithium, or additional information on the kinetics of Li-Au alloy formation.
Intervening and Letting Go: On the Adequacy of Equilibrium Causal Models
Authors: Weinberger Naftali 
Published: October 2021

AbstractCausal representations are distinguished from non-causal ones by their ability to predict the results of interventions. This widely-accepted view suggests the following adequacy condition for causal models: a causal model is adequate only if it does not contain variables regarding which it makes systematically false predictions about the results of interventions. Here I argue that this condition should be rejected. For a class of equilibrium systems, there will be two incompatible causal models depending on whether one intervenes upon a certain variable to fix its value, or ‘lets go’ of the variable and allows it to vary. The latter model will fail to predict the result of interventions on the let-go-of variable. I argue that there is no basis for preferring one of these models to the other, and thus that models failing to predict interventions on particular variables can be just as adequate as those making no such false predictions. This undermines a key argument (Dash in Caveats for causal reasoning with equilibrium models. University of Pittsburgh. PhD thesis, 2003) against relying upon causal models inferred from equilibrium data.
Genetic Risk Variants for Class Switching Recombination Defects in Ataxia-Telangiectasia Patients
Authors: Amirifar Parisa , Mehrmohamadi Mahya , Ranjouri Mohammad Reza , Akrami Seyed Mohammad , Rezaei Nima , Saberi Ali , Yazdani Reza , Abolhassani Hassan , Aghamohammadi Asghar 
Published: October 2021

Abstract
Background
Ataxia-telangiectasia (A-T) is a rare autosomal recessive disorder caused by mutations in the ataxia telangiectasia mutated (ATM) gene. A-T patients manifest considerable variability in clinical and immunological features, suggesting the presence of genetic modifying factors. A striking heterogeneity has been observed in class switching recombination (CSR) in A-T patients which cannot be explained by the severity of ATM mutations.

Methods
To investigate the cause of variable CSR in A-T patients, we applied whole-exome sequencing (WES) in 20 A-T patients consisting of 10 cases with CSR defect (CSR-D) and 10 controls with normal CSR (CSR-N). Comparative analyses on modifier variants found in the exomes of these two groups of patients were performed.

Results
For the first time, we identified some variants in the exomes of the CSR-D group that were significantly associated with antigen processing and presentation pathway. Moreover, in this group of patients, the variants in four genes involved in DNA double-strand breaks (DSB) repair signaling, in particular, XRCC3 were observed, suggesting an association with CSR defect.

Conclusion
Additional impact of certain variants, along with ATM mutations, may explain the heterogeneity in CSR defect phenotype among A-T patients. It can be concluded that genetic modulators play an important role in the course of A-T disease and its clinical severity.
The Ethics and Economics of Middle Class Romance
Authors: Slegers Roos 
Published: October 2021

AbstractThis article shows the philosophical kinship between Adam Smith and Mary Wollstonecraft on the subject of love. Though the two major 18th century thinkers are not traditionally brought into conversation with each other, Wollstonecraft and Smith share deep moral concerns about the emerging commercial society. As the new middle class continues to grow along with commerce, vanity becomes an ever more common vice among its members. But a vain person is preoccupied with appearance, status, and flattery—things that get in the way of what Smith and Wollstonecraft regard as the deep human connection they variously describe as love, sympathy, and esteem. Commercial society encourages inequality, Smith argues, and Wollstonecraft points out that this inequality is particularly obvious in the relationships between men and women. Men are vain about their wealth, power and status; women about their appearance. Added to this is the fact that most middle class women are both uneducated and encouraged by the conduct literature of their day to be sentimental and irrational. The combined economic and moral considerations of Wollstonecraft and Smith show that there is very little room for love in commercial society as they conceived it.
Applying the DSM-5 Criteria for Gambling Disorder to Online Gambling Account-Based Tracking Data: An Empirical Study Utilizing Cluster Analysis
Authors: Catania Maris , Griffiths Mark D. 
Published: October 2021

AbstractThe emergence of online gambling has raised concerns about potential gambling-related harm, and various measures have been implemented in order to minimise harm such as identifying and/or predicting potential markers of harm. The present study explored how the nine DSM-5 criteria for gambling disorder can be operationalised in terms of actual online gambling behaviour using account-based gambling tracking data. The authors were given access to an anonymised sample of 982 gamblers registered with an online gambling operator. The data collected for these gamblers consisted of their first three months’ gambling activity. The data points included customer service contacts, number of hours spent gambling, number of active days, deposit amounts and frequency, the number of times a responsible gambling tool (such as deposit limit) were removed by the gamblers themselves, number of cancelled withdrawals, number of third-party requests, number of registered credit cards, and frequency of requesting bonuses through customer service (i.e., the number of instances of ‘bonus begging’). Using these metrics, most of the DSM-5 criteria for gambling disorder can be operationalized (at least to some extent) using actual transaction data. These metrics were then applied to a sample of online gamblers, and through cluster analysis four types of online gambler based on these metrics (non-problem gamblers, at-risk gamblers, financially vulnerable gamblers, and emotionally vulnerable gamblers) were identified. The present study is the first to examine the application of the DSM-5 criteria of gambling disorder to actual gambling behaviour using online gambling transaction data and suggests ways that gambling operators could identify problem gamblers online without the need for self-report diagnostic screening instruments.
Efficient importance sampling for large sums of independent and identically distributed random variables
Authors: Ben Rached Nadhir , Haji-Ali Abdul-Lateef , Rubino Gerardo , Tempone Raúl 
Published: October 2021

AbstractWe discuss estimating the probability that the sum of nonnegative independent and identically distributed random variables falls below a given threshold, i.e., $$\mathbb {P}(\sum _{i=1}^{N}{X_i} \le \gamma )$$

P
(

∑

i
=
1

N

X
i

≤
γ
)

, via importance sampling (IS). We are particularly interested in the rare event regime when N is large and/or $$\gamma $$
γ
is small. The exponential twisting is a popular technique for similar problems that, in most cases, compares favorably to other estimators. However, it has some limitations: (i) It assumes the knowledge of the moment-generating function of $$X_i$$

X
i

and (ii) sampling under the new IS PDF is not straightforward and might be expensive. The aim of this work is to propose an alternative IS PDF that approximately yields, for certain classes of distributions and in the rare event regime, at least the same performance as the exponential twisting technique and, at the same time, does not introduce serious limitations. The first class includes distributions whose probability density functions (PDFs) are asymptotically equivalent, as $$x \rightarrow 0$$

x
→
0

, to $$bx^{p}$$

b

x
p

, for $$p>-1$$

p
>
-
1

and $$b>0$$

b
>
0

. For this class of distributions, the Gamma IS PDF with appropriately chosen parameters retrieves approximately, in the rare event regime corresponding to small values of $$\gamma $$
γ
and/or large values of N, the same performance of the estimator based on the use of the exponential twisting technique. In the second class, we consider the Log-normal setting, whose PDF at zero vanishes faster than any polynomial, and we show numerically that a Gamma IS PDF with optimized parameters clearly outperforms the exponential twisting IS PDF. Numerical experiments validate the efficiency of the proposed estimator in delivering a highly accurate estimate in the regime of large N and/or small $$\gamma $$
γ
.