bluuebunny/crossref_metadata_2025_split huggingface dataset:
Allopatric origin of sympatric whitefish morphs with insights on the genetic basis of their reproductive isolation
Authors: Fang Bohao , Momigliano Paolo , Kahilainen Kimmo K. , Merilä Juha 
Published: September 2021

AbstractThe European whitefish (Coregonus lavaretus) species complex is a classic example of recent adaptive radiation. Here we examine a whitefish population introduced to northern Finnish Lake Tsahkal in late 1960’s, where three divergent morphs (viz. littoral, pelagic and profundal feeders) were found ten generations after. Using demographic modelling based on genomic data we show that whitefish morphs evolved during a phase of strict isolation, refuting a rapid symmetric speciation scenario. The lake is now an artificial hybrid zone between morphs originated in allopatry. Despite their current syntopy, clear genetic differentiation remains between two of the three morphs. Using admixture mapping three quantitative trait loci associated with gonad weight variation, a proxy for sexual maturity and spawning time, were identified. We suggest that ecological adaptations in spawning time evolved in allopatry are currently maintaining partial reproductive isolation in the absence of other barriers to gene flow.
Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
Authors: Das Bhaba K , Wang Lei , Fujiwara Toshifumi , Zhou Jian , Aykin-Burns Nukhet , Krager Kimberly J , Lan Renny , Mackintosh Samuel G , Edmondson Ricky , Jennings Michael L , Wang Xiaofang , Feng Jian Q , Barrientos Tomasa , Gogoi Jyoti , Kannan Aarthi , Gao Ling , Xing Weirong , Mohan Subburaman , Zhao Haibo 
Published: September 2021

AbstractIncreased intracellular iron spurs mitochondrial biogenesis and respiration to satisfy high-energy demand during osteoclast differentiation and bone-resorbing activities. Transferrin receptor 1 (TFR1) mediates cellular iron uptake through endocytosis of iron-loaded transferrin and its expression increases during osteoclast differentiation. Nonetheless, the precise functions of TFR1 and TFR1-mediated iron uptake in osteoclast biology and skeletal homeostasis remain incompletely understood. To investigate the role of TFR1 in osteoclast lineage cells, we conditionally deleted Tfr1 gene in myeloid precursors or mature osteoclasts by crossing Tfr1- floxed mice with LysM-Cre and Ctsk-Cre mice, respectively. Skeletal phenotyping by µCT and histology unveiled that loss of Tfr1 in osteoclast progenitor cells resulted in a three-fold increase in trabecular bone mass in the long bones of 10-week old female but not male mice. Although high trabecular bone volume in long bones was seen in both male and female mice with deletion of Tfr1 in mature osteoclasts, this phenotype was more pronounced in female knockout mice. Mechanistically, disruption of Tfr1 expression attenuated mitochondrial metabolism and cytoskeletal organization in mature osteoclasts, leading to decreased bone resorption with no impact on osteoclastogenesis. These results indicate that Tfr1-mediated iron uptake is specifically required for osteoclast function and is indispensable for bone remodeling.
Intracellular force comparison of pathogenic KIF1A, KIF5, and dynein by fluctuation analysis
Authors: Hayashi Kumiko , Matsumoto Shiori , Naoi Takuma , Idobata Yuki 
Published: September 2021

AbstractIn mammalian cells, there exist approximately 40 types of microtubule motor proteins that are assigned to specific cargo deliveries. For example, the kinesin-1 family motor KIF5 is the major motor responsible for anterograde mitochondrial transport, whereas the kinesin-3 family motor KIF1A is responsible for synaptic vesicle precursor transport. In contrast, cytoplasmic dynein is responsible for retrograde transport of nearly all cargos. The force and velocity of these microtubule motors have been investigated in in-vitro single-molecule experiments. In the present study, we compared the intracellular force and velocity of various types of motors in the mammalian neuronal axon obtained by non-invasive force measurement (fluctuation analysis) and extreme value analysis with those obtained by previous single-molecule experiments. As we found a high correlation between our results and the previous results, we next investigated synaptic vesicle precursor transport by hereditary spastic paraplegia-associated KIF1A variants (V8M, R350G, and A255V). KIF1A-V8M and KIF1A-A255V exhibited force and velocity impairment in mammalian neuronal axons, whereas the physical property of KIF1A-R350G was similar to that of the wild type. We believe that the development of new analytical techniques for investigating intracellular cargo transports is helpful to elucidate the molecular mechanism of KIF1A-associated neurological disorders.Statement of SignificanceRecent in-vitro single-molecule experiments have clearly revealed that microtubule motors only fully exert their functions when fully equipped with the proteins associated with cargo vesicle transport. This emphasizes the significance of intracellular physical measurements, in which the motors should fully function. In addition to motor force and velocity, the number of motors transporting a single cargo together is an important physical quantity to characterize cargo transport, but is difficult to estimate using in-vitro single-molecule experiments. In this study, we aimed to extract physical information on microtubule motors in the intracellular environment.
Real-time monitoring and analysis of SARS-CoV-2 nanopore sequencing with minoTour
Authors: Munro Rory , Holmes Nadine , Moore Christopher , Carlile Matt , Payne Alexander , Santos Roberto , Loose Matt 
Published: September 2021

AbstractMotivationThe ongoing SARS-CoV-2 pandemic has demonstrated the utility of real-time analysis of sequencing data, with a wide range of databases and resources for analysis now available. Here we show how the real-time nature of Oxford Nanopore Technologies sequencers can accelerate consensus generation, lineage and variant status assignment. We exploit the fact that multiplexed viral sequencing libraries quickly generate sufficient data for the majority of samples, with diminishing returns on remaining samples as the sequencing run progresses. We demonstrate methods to determine when a sequencing run has passed this point in order to reduce the time required and cost of sequencing.ResultsWe extended MinoTour, our real-time analysis and monitoring platform for nanopore sequencers, to provide SARS-CoV2 analysis using ARTIC network pipelines. We additionally developed an algorithm to predict which samples will achieve sufficient coverage, automatically running the ARTIC medaka informatics pipeline once specific coverage thresholds have been reached on these samples. After testing on run data, we find significant run time savings are possible, enabling flow cells to be used more efficiently and enabling higher throughput data analysis. The resultant consensus genomes are assigned both PANGO lineage and variant status as defined by Public Health England. Samples from within individual runs are used to generate phylogenetic trees incorporating optional background samples as well as summaries of individual SNPs. As minoTour uses ARTIC pipelines, new primer schemes and pathogens can be added to allow minoTour to aid in real-time analysis of pathogens in the future.Availability and ImplementationSource code and documentation is available at https://github.com/LooseLab/minotourapp.Supplementary informationSupplementary data are available fromhttps://github.com/LooseLab/artic_minotour_analyses.
The first infrared beamline at the Middle East SESAME synchrotron facility
Authors: Kamel Gihan , Lefrancois Stephane , Moreno Thierry , Al-Najdawi Mohammad , Momani Yazeed , Abbadi Anas , Paolucci Giorgio , Dumas Paul 
Published: September 2021

SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is the only synchrotron light facility in the Middle East and neighboring regions, officially opened in 2017. Among the identification and construction of the first operational beamlines, infrared spectromicroscopy was selected as one of the two beamlines to be opened to the general users' program (the so-called Day-1 beamlines). Being one of the most demanded techniques by various scientific communities in the Middle East, the beamline has been designed and implemented in the framework of a collaboration agreement with the French synchrotron facility, SOLEIL. The design, construction and initial performances of the IR beamline (D02-IR), nowadays operational, are reported.
De gustibus non est disputandum: analysis of the relationship between cultural omnivorousness and food
Authors: Kılıçlar Arzu , Sarıkaya Gizem Sultan , Şahin Ayşe , Bozkurt İsmail 
Published: September 2021

PurposeThis study aims to synthesize theoretical and empirical studies on the food dimension of developments in cultural omnivorousness. Cultural omnivorousness is an antithesis which Peterson developed against Bourdieu's stratification theory that emerged in 1992, and it has been the subject of scientific research in different dimensions, including literature, music, art and food.Design/methodology/approachIn this study, databases were systematically searched to identify publications on cultural omnivorousness and food. The data obtained in the study was appraised using the checklist of preferred reporting items for systematic reviews and meta-analyses (PRISMA).FindingsThis study concluded that research on cultural omnivoriusness and food is often investigated from a demand perspective. Findings indicated that the relationship between food and cultural omnivorousness is focused on the axis of eating out, restaurant types and preferences, regions where restaurants are located, liked/preferred food, vegetarianism, the healthy/unhealthy state of food, locality and economic value of preferred food. Moreover, comparing the reviewed study results, it was identified that multiple regression was mostly used in quantitative research, and content analysis was benefited in qualitative research.Research limitations/implicationsThe reviewed studies were limited to articles with open access and peer-reviewed journals over the period 1990–2020. In addition, this study adopted a qualitative research approach. Another limitation of the research is that it only examined cultural omnivorousness in terms of food.Practical implicationsIt is noticed that the results of the research conducted regarding the relationship between cultural omnivorousness and food vary by countries and cities. The reason for this situation might be the different historical processes and development levels of the countries and the difference in the symbols represented by food in this process. Additionally, in practical terms, this research offers some implications for how the relationship between cultural omnivorousness and food can be used by supply. Restaurants from a consumer perspective and destinations from a tourist perspective can use cultural omnivorousness as a strategic element in their marketing planning.Originality/valueThe literature on cultural omnivorousness is used to make sense of a striking phenomenon, namely the tastes/likes of individuals in the middle and upper classes. However, there has not been found such an examination of food and its use in cultural omnivorousness studies. This article fills the identified gap, adding to the discussion on food and cultural omnivorusness and provides a related research agenda.
Career self-management perceptions reflected in the psychological contract of virtual employees: a qualitative and quantitative analysis
Authors: Gazit Lee , Zaidman Nurit , Van Dijk Dina 
Published: September 2021

PurposeThe question of responsibility for career development is critical for virtual employees who work remotely. The purpose of this paper is to (1) compare the perceptions of virtual and on-location employees in the high-tech industry about where responsibility lies for career management, as reflected in their psychological contract (PC) and (2) evaluate the ability of virtual employees to exercise behaviors capable of enhancing their career development.Design/methodology/approachA mixed-methods approach was used for this study. Study 1 consisted of semi-structured interviews (N = 40) with virtual and on-location employees working for the same high-tech organization, exploring perceptions responsibility for career self-management as captured by their PCs. Study 2, a quantitative survey of virtual and on-location employees (N = 146) working for various organizations in the high-tech sector, examined perceptions of career self-management through the perceived PC, as well as the perceived ability to exercise behaviors that would enhance career development.FindingsBoth categories of employees assumed that they, together with their direct manager, had responsibility for managing their career development. Nevertheless, virtual employees had lower expectations of support from their managers in this respect (Study 1) and felt that they actually received less support from their managers (Study 2). The results of both studies show, however, that virtuality does not have any significant effect on employees’ self-reported proactive career-influencing behaviors.Originality/valueThe study contributes to existing research by highlighting the perceived joint responsibility for career management and the critical role played by line management in this regard and by showing that virtuality does not have a significant effect on employees’ self-reported proactive career-influencing behaviors.
Expanding the transdisciplinary conversation towards pluriversal distributive disaster recovery: development ethics and interculturality
Authors: Waldmüller Johannes M. 
Published: September 2021

PurposeFrom a Latin American decolonial and transdisciplinary perspective, this article expands the increasingly relevant conversation about disaster ethics, not only in depth and scope but also both interdisciplinarily and interculturally. By reviewing key points of development ethics that are closely related but underexplored, it makes the case for focusing on disaster recovery as a relevant distributive phase for improving future prevention and mitigation, while remedying long-standing injustices.Design/methodology/approachTo do so, against the backdrop of recently emerging postcolonial, decolonial and structural approaches to disaster and vulnerability studies, the article presents a theoretical conversation between decolonial studies, development ethics, intercultural practice and philosophy, and disaster ethics beyond utilitarian approaches.FindingsSo far, development and disaster ethics remain worlds apart, despite their relevant convergence around the key notion of “recovery” and its underlying normative determination. This article identifies that prevailing utilitarian ethics in emergency response, in addition to their problematic universalization, have prevented further engagement with deontological and process-based principles, including a nuanced distributive sensitivity. As a result of such cross-fertilization, methodological individualism in an intercultural encounter is suggested, as well as continued engagement with pluriversal deliberation about key ethical values and notions regarding disaster risk and response.Originality/valueCalling for distributive bottom-up engagement beyond professional and academic boundaries, this article presents a new direction for decolonising disaster ethics, so far unexplored, seeking to bridge the value gap between development and disaster efforts, planning and prevention.
Robotized interior finishing operations with visual feedback
Authors: Jiang Xin , Li Xiang 
Published: September 2021

Purpose
This paper aims to address the problem of integrating sensor feedback in robotized interior finishing operations. Its motivation is to finally realize automatic operations necessitating no human intervention. A vision-based approach is proposed for monitoring the execution status and changing the action accordingly.

Design/methodology/approach
First, a robotic system is proposed which can realize two typical interior finishing operations, namely, putty applying and wall sanding. Second, a new method based on a deep neural network is proposed to process the visual information capturing the execution status of the interior finishing operations. It helps to determine essential parameters on where should be processed and how to execute the corresponding operation. With the proposed method, vision information is embedded into the execution of interior finishing in a closed loop style.

Findings
The experiments demonstrate the feasibility of the proposal and reveal problems for further improvement of the autonomous interior finishing robot.

Originality/value
This provides an original insight into robotized interior finishing by addressing an attempt on integrating visual feedback into the manual process.
Why do people shop together around the same screen?
Authors: Roten Yonathan Silvain , Vanheems Régine 
Published: September 2021

Purpose
Increasingly, consumers shopping online are not doing so alone. This paper aims to identify motivations for and barriers to shopping together with relatives or friends on the same screen.

Design/methodology/approach
This study proposes an interdisciplinary theoretical framework investigating “sharing” and related commercial practices. It adopts an exploratory qualitative methodology as the phenomenon of screen sharing has not been widely investigated in prior consumer behavior literature.

Findings
Social and utilitarian motives elicit joint shopping in stores and collaborative consumption. This study reveals a third motive, related to the need for control, that drives shopping on the same screen. Screen sharing can increase efficiency, social bonds and control, due to the transparent presentation of information on the screen, but it also can cause inefficiency, social tension and struggle for control over the device.

Research limitations/implications
Screen-sharing motives reflect different logics for sharing: distribution (use with), communication (discuss with) and collaboration (control with). Defining further antecedents and consequences of joint shopping on the same screen represents relevant goals for further research.

Practical implications
By adapting their online platforms, brands can provide more agreeable, efficient and empowering experiences to screen-sharing shoppers, and thus gain competitive advantages.

Originality/value
Marketers generally assume online shoppers are alone at their screens, but in practice, many of them are often browsing together. Especially for families confined together at home, shopping together online constitutes a common practice.
Banking market structure and efficiency: an assessment of the USA and Canada
Authors: U-Din Salah , Tripe David 
Published: September 2021

PurposeThe study aims to analyze the changes in banking market structure and their impact on the bank efficiency.Design/methodology/approachThis study uses a one-stage stochastic frontier analysis (SFA) to compare the impact of the market structure and the GFC on the economic efficiency of the major banks in both countries.FindingsA significant negative impact of the GFC is observed on bank efficiency. Overall, Canadian banks posted better efficiency scores than their American counterparts. Additionally, cost-efficient banks are found to be more resilient to crises and more profit-efficient in the post-GFC period. The authors found that market power had a positive impact on the cost and profit efficiency of banks. Higher levels of equity, market power and concentration helped banks be more cost-efficient.Research limitations/implicationsOnly large banks are selected for study although it represents the majority stake of both banking sectors.Practical implicationsBanking regulators should include more measures to assess the banking market structure and performance.Originality/valueAs per the best knowledge of the authors, it is the first study to assess the change in banking market structure and efficiency of the US and Canadian banking sectors in the post-GFC period.
Antecedents of mobile advertising value: a precedence analysis using the hybrid RIDIT-GRA approach
Authors: Sharma Anshuman , Pathak Vivek Kumar , Siddiqui Mohammad Qutubuddin 
Published: September 2021

Purpose
Massive transformations in mobile communication technologies have forced marketers to recognize and emphasize the factors that influence consumers’ perception of advertising value. This paper aims to explore and rank the various antecedents of advertising value as perceived by consumers to offer meaningful conclusions to marketers on mobile platforms.

Design/methodology/approach
Responses were collected from 483 consumers using a shopping mall intercept survey and analyzed using SPSS to confirm reliability, validity and data reduction. The Relative to an Identified Distribution (RIDIT) analysis and Grey Relational Analysis (GRA) methods were then applied to prioritize the scale items of the antecedents of mobile advertising value.

Findings
Five antecedents of advertising value were found: credibility, entertainment, informativeness, irritation and message relevance. A priority ranking was allotted to the antecedents’ scale items using the RIDIT analysis and was verified via GRA results with a correlation of 98% between the rankings of the two independent methodologies.

Practical implications
The findings provide a roadmap to determine which antecedents of mobile advertising value have a higher or lower impact on consumers’ overall perceptions of the advertisements they are exposed to on mobile platforms.

Originality/value
This study aims to use first-hand data to prioritize the underlying antecedents of mobile advertising value, which has rarely been done to the best of the authors’ knowledge. It also used two different approaches in a single study to rank the dimensions, thus producing more valid results.
Ethical aspects of voice assistants: a critical discourse analysis of Indonesian media texts
Authors: Arifin Anisa Aini , Lennerfors Thomas Taro 
Published: September 2021

Purpose
Voice assistant (VA) technology is one of the fastest-growing artificial intelligence applications at present. However, the burgeoning scholarship argues that there are ethical challenges relating to this new technology, not the least related to privacy, which affects the technology’s acceptance. Given that the media impacts public opinion and acceptance of VA and that there are no studies on media coverage of VA, the study focuses on media coverage. In addition, this study aims to focus on media coverage in Indonesia, a country that has been underrepresented in earlier research.

Design/methodology/approach
The authors used critical discourse analysis of media texts, focusing on three levels (text, discourse practice and social practice) to study how VA technology was discussed in the Indonesian context and what power relations frame the representation. In total, 501 articles were collected from seven national media in Indonesia from 2010 to 2020 and the authors particularly focus on the 45 articles that concern ethics.

Findings
The ethical topics covered are gender issues, false marketing, ethical wrongdoing, ethically positive effects, misuse, privacy and security. More importantly, when they are discussed, they are presented as constituting no real critical problem. Regarding discursive practices, the media coverage is highly influenced by foreign media and most of the articles are directed to well-educated Indonesians. Finally, regarding social practices, the authors hold that the government ideology of technological advancement is related to this positive portrayal of VAs.

Originality/value
First, to provide the first media discourse study about ethical issues of VAs. Second, to provide insights from a non-Western context, namely, Indonesia, which is underrepresented in the research on ethics of VAs.