bluuebunny/crossref_metadata_2025_split huggingface dataset:
Review of the Mechanical Properties of High-Strength Alloys at Cryogenic Temperatures
Authors: Umezawa Osamu 
Published: March 2021

Abstract
To advance the understanding of metallic materials for structural components at cryogenic temperatures, a review of previous studies on the mechanical properties of austenitic stainless steels, titanium alloys, aluminum alloys, and copper alloys is presented herein. In particular, the evaluation of strength and toughness balance intends to clarify key differences between these alloys to facilitate better alloy design and potentially bolster further alloy development. Several key points on cryogenic mechanical tests are also introduced. Temperature control, testing tools, and test conditions should be properly calibrated to avoid experimental errors. Furthermore, substantial progress for subsurface crack initiation in high-cycle fatigue at cryogenic temperatures is presented, in which the mechanism of subsurface crack generation is highlighted as a key design consideration in microstructure of high-strength alloys.
Family and Child Risk Factors for Early-Life RSV Illness
Authors: Fitzpatrick Tiffany , McNally J. Dayre , Stukel Thérèse A. , Lu Hong , Fisman David , Kwong Jeffrey C. , Guttmann Astrid 
Published: March 2021

BACKGROUND AND OBJECTIVES:
Most infants hospitalized with respiratory syncytial virus (RSV) do not meet common “high-risk” criteria and are otherwise healthy. The objective of this study was to quantify the risks and relative importance of socioeconomic factors for severe, early-life RSV-related illness. We hypothesized several of these factors, particularly those indicating severe social vulnerability, would have statistically significant associations with increased RSV hospitalization rates and may offer impactful targets for population-based RSV prevention strategies, such as prophylaxis programs.

METHODS:
We used linked health, laboratory, and sociodemographic administrative data for all children born in Ontario (2012–2018) to identify all RSV-related hospitalizations occurring before the third birthday or end of follow-up (March 31, 2019). We estimated rate ratios and population attributable fractions using a fully adjusted model.

RESULTS:
A total of 11 782 RSV-related hospitalizations were identified among 789 484 children. Multiple socioeconomic factors were independently associated with increased RSV-related admissions, including young maternal age, maternal criminal involvement, and maternal history of serious mental health and/or addiction concerns. For example, an estimated 4.1% (95% confidence interval: 2.2 to 5.9) of RSV-related admissions could be prevented by eliminating the increased admissions risks among children whose mothers used welfare-based drug insurance. Notably, 41.6% (95% confidence interval: 39.6 to 43.5) of admissions may be prevented by targeting older siblings (eg, through vaccination).

CONCLUSIONS:
Many social factors were independently associated with early-life RSV-related hospitalization. Existing RSV prophylaxis and emerging vaccination programs should consider the importance of both clinical and social risk factors when determining eligibility and promoting compliance.
Bibliometric Analysis of Fuzzy Logic Research in International Scientific Databases
Authors: Radu Valentin , Radu Florin , Tabirca Alina Iuliana , Saplacan Silviu Ilie , Lile Ramona 
Published: March 2021

The purpose of this study is to explore the Web of Science Database (WOS) and review the significant contributions to the research of Fuzzy Logic or Fuzzy Sets theory from the beginning to the present. This study analyzes the most eminent authors, institutions, countries, and journals in Fuzzy Logic research by applying science mapping methods and bibliometric measures. Also, we paid attention to link strength and h-index to represent the visibility, influence, and link between the representative authors. Moreover, we added descriptive statistics to highlight strong linearity and a connection between fuzzy publications and Fuzzy Logic research. Also, we applied regression analyses and prevision functions to predict the evolution of the Fuzzy Logic topic.
The results showed a significant increase in the number of papers published annually in a portfolio of internationally representative journals. This leads us to the idea that Fuzzy Logic research is now a transdisciplinary topic that continually develops. Therefore, it can be found in more and more related areas such as artificial intelligence, IoT, medicine, economics, or the environment. Most of the results are consistent with other bibliometric studies. Still, some results are different, results related to the current cited works that show a polarization in the Asia area and the top journals that is continuously changing depending on the number of papers and the quotations of scientific personalities that publish. We used the VOS Viewer software to map the main trends in the field. The results indicate that the use of concepts has long exceeded traditional boundaries.
Islamic Finance, Small and Medium Enterprises and Job Creation in Turkey: An Empirical Evidence (2009-2017)
Authors: Benbekhti Seyf Eddine , Boulila Hadjer , Bouteldja Abdelnacer 
Published: March 2021

The aim of this paper is to investigate if Islamic finance can solve the funding problem of SMEs and facilitate access to finance for SMEs, and how can these last participate in job creation in Turkey in order to face the problem of unemployment. The paper adopts a Vector Autoregressive model (VAR) based on monthly data (2009-2017). The results revealed that Islamic finance is a golden opportunity and a sufficient alternative financial source for SMEs. In addition, as SMEs can reduce unemployment by contributing to the labor market. This study contributes to the existing literature by presenting a promising financing tool to the prospective borrowers of SMEs (farmers, underserved groups, and small entrepreneurs) which is Islamic financing. This alternative can be an effective tool for both muslim and non-muslim countries in regard that conventional finance is more expensive and SMEs are unable to pay high interest rates. It would also help in establishing low unemployment levels. This paper suggested that Islamic banks and Islamic financial institutions should converge more on the SMEs by providing funding to SMEs which would lead to boosting production and economic development.
Centrally acting cholecystokinin induces depressor circulatory effects in haemorrhage-shocked rats
Authors: Jasikowska Karolina , Zając Magdalena , Jochem Jerzy 
Published: March 2021

WstępCholecystokinina (CCK) należy do hormonów peptydowych układu pokarmowego regulujących trawienie lipidów i białek, a ponadto jest ośrodkowym neurotransmiterem/neuromodulatorem. Po podaniu dożylnym wywołuje efekt resuscytacyjny u szczurów we wstrząsie krwotocznym. Ze względu na fakt, iż CCK może wpływać bezpośrednio i pośrednio na czynność ośrodka sercowo-naczyniowego, celem pracy było zbadanie działania pochodnej siarczanowej oktapeptydu CCK (CCK-8) podawanej do komory bocznej mózgu (<i>intracerebroventricularly</i> – icv) w fazie hamowania czynności układu współczulnego we wstrząsie krwotocznym.Materiał i metodyBadania przeprowadzono u samców szczurów szczepu Wistar w znieczuleniu ogólnym (ketamina [100 mg/kg]/ksylazyna [10 mg/kg]), u których wywołano nieodwracalny wstrząs krwotoczny (0% przeżycia 2 h) ze średnim ciśnieniem tętniczym (<i>mean arterial pressure</i> – MAP) 20–25 mmHg. W 5 min krytycznej hipotensji szczurom podawano icv CCK-8 (5, 15 nmol) lub 0,9% roztwór NaCl (5 μl).WynikiKrwotok prowadził do obniżenia ciśnienia tętna (<i>pulse pressu</i>re – PP), częstości rytmu serca (<i>heart rate</i> – HR) oraz wzrostu nerkowego (<i>renal vascular resistance</i> – RVR) i krezkowego oporu naczyniowego (<i>mesenteric vascular resistance</i> – MVR). W grupie kontrolnej nie stwierdzono wzrostu badanych parametrów układu krążenia, a średni czas przeżycia wynosił 32,5 ± 5,1 min. CCK-8 wywoływała zależne od dawki spadki MAP, PP i HR ze wzrostem RVR i MVR, a także skracała czas przeżycia w porównaniu ze zwierzętami kontrolnymi.WnioskiOśrodkowo działająca CCK-8 wywołuje działanie depresyjne na układ krążenia u szczurów we wstrząsie krwotocznym.
COVID-19 Contact Tracing Conundrums: Insights From the Front Lines
Authors: Schneider John , Love Willie , Rusie Laura , Flores Ariana , Tadesse Beth , Hazra Anu , Munar David 
Published: March 2021

COVID-19 contact tracing is an induction social network intervention in which the structure of the social network is leveraged to deploy proven COVID-19 interventions such as testing and social distancing. The Howard Brown Health organization has rapidly expanded to include COVID-19 testing, contact tracing, and linkage to resources since the first cases were identified in Chicago, Illinois. COVID-19 is penetrating the most vulnerable networks in the United States; existing inequities are widening as community resources and organizations have had to place services on hold. Here we address several questions that arise as organizations build capacity for contact tracing, including questions involving the potential impact of contact tracing, stakeholders who could be involved, the timing of contact tracing deployment, and the impact potential for digital technology. Contact tracing is critical at later stages of epidemic decline given the potential for isolated outbreaks as larger events, schools, stadiums, and festivals reopen. Local contact tracing efforts can have other indirect benefits with respect to limiting transmission, such as increasing testing rates and addressing structural barriers through provision of life-saving resources and access to crucial social support.
Effect Of Water Content On Characteristics Fuel From The Municipal Solid Waste Through The Pyrolysis Process
Authors: Rosyadi Imron , Caturwati Ni Ketut , Fauzi Ahmad 
Published: March 2021

The increase in the population of Indonesia is proportional to the increase in the amount of waste produced. Municipal solid waste (MSW) especially organic waste, can be used as solid fuel by means of the torefaction process. Torefaction is a thermo-chemical heat treatment method for biomass conversion that takes place at a temperature of 200oC to 300oC under conditions of atmospheric pressure and in the absence of oxygen. The purpose of this study was to determine the effect of moisture content on calorific, proximate and ultimate values ​​of torefaction samples using municipal solid waste. Setting the water content in the mixed sample (30% rice + 70% wood) with variations in moisture content of 30%, 40%, and 50%; and rice and wood samples with variations in moisture content of 40% and 50%. The torefaction was carried out at a temperature of 300oC for one hour and inert gas N2. Torefaction products have been tested contain of the calorific value, proximate testing, and ultimate testing. The results obtained were the best calorific value in the rice sample, the moisture content of 40% was 6351.1 cal / g or equivalent to sub-bituminous coal. The proximate and ultimate results of the best heating value are rice samples with 40% moisture content, fixed carbon 62.95%, volatile matter 27.85%, moisture 7.06%, ash 2.14%, carbon 71.85%, hydrogen. 2.80%, nitrogen 3.17%, and sulfur 0.05%. The calorific value calculation method that is almost close to the test results is the Dulong method, with an average error percentage of 1.63%.
40-YEAR BIBLIOMETRIC ANALYSIS OF WAQF: ITS CURRENT STATUS AND DEVELOPMENT, AND PATHS FOR FUTURE RESEARCH
Authors: Aldeen Khaled Nour 
Published: March 2021

Waqf (Islamic endowment) has received great attention from contemporary scholars, in line with the increasing attention being paid to social welfare. However, it is conceptually unclear, with no consensus having been reached among researchers on its current status. This study provides a brief overview of recent Waqf research developments, hence paving the way for future research. The research employs a bibliometric approach to analysing and summarising the trends and status quo in Waqf growth. Only articles written in English extracted from both the Web of Science and Scopus databases were considered for the study. The paper is an attempt to establish a solid conceptual base and to suggest directions for future research. The research provides a clear picture of the growth of Waqf, and indicates research gaps by reaching comprehensive conclusions about what has been achieved in the field. It hence opens new doors for scholars to develop innovative Waqf models to bridge socioeconomic issues. Our findings show that Indonesian and Malaysian scholars and their educational institutions have had a robust research commitment to the theme of Waqf during the last forty years. However, there is a lack of research on the countries where Waqf was first practised.
A protocol for the generation of blastocyst-like structures from human pluripotent stem cells
Authors: Yu Leqian , Wei Yulei , Schmitz Daniel A. , Sakurai Masahiro , Wu Jun 
Published: March 2021

Abstract
The recent development of stem-cell-based embryo models open new avenues for studying early development in vitro, including humans1. Here we report a protocol for the generation of human blastocyst-like structures from naïve human pluripotent stem cells (hPSCs). These structures, termed human blastoids, provide an accessible, scalable, versatile, and manipulable 3D model to study early human development, understand early pregnancy loss, and gain insights into early developmental defects.
Clinical and imaging analysis to evaluate the response of patients with anti-DPPX encephalitis to immunotherapy
Authors: Xiao Jun , Fu Pei-cai , Li Zhi-jun 
Published: March 2021

Abstract
Background: To report the main spectrum, new clinical and imaging characteristics of dipeptidyl-peptidase-like protein 6 (DPPX) antibody-associated encephalitis, and evaluate the effect of immunotherapy.Methods: A retrospective analysis of nine patients reported describing the clinical and immunological features was performed, and all previously reported cases were reviewed. A cell-based indirect immunofluorescence assay with human embryonic kidney 293 cells transfected with DPPX was used. Results: Nine patients were identified (median age, 51 years; range, 14–65 years) with prodromal fever, diarrhea, or weight loss, followed by a rapidly progressive encephalopathy characterized by cognitive disorder. One patient who received methylprednisolone therapy and a trail of tacrolimus showed substantial improvement and had no relapse in the six-month follow-up. Our comprehensive literature review demonstrated that a total of 53 cases were reported, of which more than half had prodromal weight loss (52.8%), and gastrointestinal disorders (58.5%). Cognitive (74.6%) and brainstem/spinal cord disorders (75.5%) were the most common major symptoms. Our study is the first to report three patients with anti-DPPX encephalitis who had sleep disorder of rapid eye movement sleep behavior disorder (RBD), limb paralysis (two), severe pleocytosis and elevated protein levels (two) in the cerebrospinal fluid, and increased T2/FLAIR signal abnormalities in the bilateral hippocampus, temporal lobe, amygdala, basal ganglia, thalamus, centrum semiovale, and frontal and parietal lobes in seven cases (77.8%).Conclusion: Our study expanded the clinical and imaging phenotype of anti-DPPX- encephalitis. We also reported the use of tacrolimus for long-term immunosuppressant therapy in anti-DPPX encephalitis, with substantial improvement and no relapse during a follow-up period of 6 months. Further studies elucidating the entire clinical spectrum of anti-DPPX encephalitis, pathogenic roles, and prognosis under long-term immunosuppressive therapy are warranted.
Business Intelligence Applied to The Consumption of Iodinated Contrast Agents in Computed Tomography Scans
Authors: ANDRADE JOSE RODRIGO , Blomberg Luciano 
Published: March 2021

Abstract
Background: The management of the use of iodinated contrast agents (ICA) in the computed tomography (CT) has clinical and financial impacts; however, the approaches in the current research setting have limitations with regard to their exploration of the theme. This work describes the application of the stages of a process of business intelligence (BI), from the formulation of business questions, the building of a research database, and the adaptation of a multidimensional model, to the creation of dashboards to give support to the decision-making process in a hospital. This research aims to apply and document a BI process that provides support to the decision making of managers, so the use of ICA can be better managed, allowing for the identification of situations in which the material was wasted using a study applied to the hospital field.Methods: An applied exploratory research with a quantitative approach in a database made up by 24 variables and 35,388 records extracted from the RIS (Radiology Information System) that is used by the General Hospital of Porto Alegre - HCPA. The software used, supplied by AGFA Healthcare, were the Qdoc system (version 6.2.0) and the Impax BI (Version 11.1.1) for, respectively, data entry and data exploration. At the end of the process, a total of 48 variables was considered.Results: The BI process applied allowed for the identification of situations in which ICA was being wasted during the operationalization of the volume/mass ratio of the agent injected in the patient. It also offered the necessary substantiation for the managers to formulate plans, actions, and controls associated to the use of the material. This work made it possible to diminish in 15.65% the total consumption of ICA injected in the patients who underwent the CTAB1 exam (full CT scan of the abdomen), with a projected economy of US$ 10,039.95, for the performance of this exam from 2020 on. The measuring of the impact and the relevance of the process was 99.6% positive, according to the evaluation of the managers. Conclusions: This research generated clinical and financial benefits for the HCPA, a positive evaluation by the managers and the generation of new knowledge, which can be shared with other public or private health organizations.
Influence of Abrasive Water Jet parameters on the surface integrity of Inconel 718
Authors: Salinas Lorena Cano , Moussaoui Kamel , Hejjaji Akshay , Salem Mehdi , Hor Anis , Zitoune Redouane 
Published: March 2021

Abstract
Inconel 718 (IN718) is a precipitation hardened nickel-base super-alloy exhibiting high strength and good corrosion resistance at elevated temperatures and on the downside it is characterized by poor machinability. Abrasive Water Jet (AWJ) process, offers a potential method to machining difficult-to-cut materials such as IN718. The present work investigates the influence of Abrasive Water Jet parameters on surface roughness, topography, depth of cut and residual stress when milling IN718. Surface characterization was conducted through 3D optical microscopy and SEM techniques. Residual stresses were measured in longitudinal and transverse directions with respect to the machining path using X-ray diffraction (XRD) technique. The obtained results showed that milled surfaces have a homogeneous texture with embedded abrasive particles and high surface roughness. AWJ process introduced high compressive residual stresses with similar order of level in both directions (X and Y). In addition, it was observed that jet pressure is the most influencing parameter on roughness and depth of cut, whilst traverse speed and step-over distance had a significant effect on the residual stress. Based on the experimental analysis, an empirical model to predict the depth of cut was proposed. The validation of the proposed model, has shown around 5% error in the predicted and actual pocket depth.
Hydrogeochemistry of intermittent alluvial aquifers controlling arsenic and fluoride contamination for corresponding influencing health risk assessment
Authors: Sathe Sandip Sampatrao , Mahanta Chandan , Subbiah Senthilmurugan 
Published: March 2021

Abstract
Identification and management of safe groundwater supply in a high As and F− contaminated region is a major concern facing most of the developing countries worldwide. This study provides a comprehensive hydrogeochemistry result for a complex hydro-stratigraphy soil aquifer, which is bound between the Shillong plateau and Himalayan ranges in the North-Eastern region of India. In this study, distinct contaminated regions of As and F− were identified in rainy (n = 94) and winter (n = 50) seasons groundwater samples. The maximum dissolved concentration of As was measured as 71 µg L− 1 in rainy and 211 µg L− 1 in winter season groundwater samples, whereas maximum F− concentration was measured as 7 mg L− 1 in rainy and 6 mg L− 1 in winter season groundwater samples. Identified minerals saturation condition, weathering, and dissolution results of hydrogeochemistry were well corroborated with the Bivariate plot, Gibbs and Pourbaix diagrams. Results of health risk assessment showed that population of age below 18 years old are prone to carcinogenic diseases and symptoms of non-carcinogenic health risk due to daily consumption of As contaminated groundwater. Children of age below 18 years old, in total 39% (i.e. 6834) and 64% (i.e. 13937) were found more susceptible to arsenic ingestion effect. The male population was found prone to As cancer risk than the female population. Overall, this study provides a critical result about the cause of high As and F− concentration in groundwater and health risk assessment, it provides a prime concern matter for the young generation which is at higher risk of As cancer.
CD248(TEM1/CD164L1/Endosialin): A new molecular target for anti-angiogenic therapy in Pancreatic ductal adenocarcinoma
Authors: Zhang Huan , Dai Zhujiang , Liao Yiqun , Yan Cheng , Zhao Bin , Liu Tian , Zhang Jie , Xing Juan , Zhang Wenjie , Zhang Jingqiu , Wang Daorong , Tang Dong 
Published: March 2021

Abstract
Background: Pancreatic ductal adenocarcinoma (PDCA) is one of the malignant tumors with the worst prognosis with a 5-year survival rate of <1%, which is known as the "king of cancers". At present, there is a lack of effective early diagnosis and treatment plan for pancreatic cancer. Therefore, there is an urgent need to understand the molecular mechanisms of pancreatic cancer to generate innovative approaches for the development of effective early diagnosis and treatment strategies.Methods: In this study, we performed single gene pan-cancer analysis, gene co-expression analysis and gene regulatory correlation analysis to understand the molecular mechanism of CD248 in pancreatic cancer using bioinformatics tools. Additionally, we provided potential molecular targets for pancreatic cancer treatment by constructing the lncRNA-miRNA-gene network axis.Results: The results showed that CD248 is differentially expressed in normal and tumor tissues, and abnormally high expression predicts poor prognosis, is a proto-oncogene in pancreatic cancer. Besides, CD248 is associated with angiogenesis of tumors. We obtained three new lncRNA-miRNA-gene network axes, namely AC008040.1-hsa-miR-200c-3p-CD248 axis, AC055822.1-hsa-miR-200c-3p-CD248 axis, RRN3P2-hsa-miR-200c-3p-CD248 axis that provide promising molecular targets for anti-angiogenic therapy and diagnostic biomarkers for pancreatic cancer.Conclusion: In conclusion, this study shows that over-expression of CD248 (TEM1/CD164L1/Endosialin) is always present in breast cancer and predicts a poor prognosis, associated with tumor angiogenesis, suggesting it as an attractive therapeutic target for pancreatic cancer.