bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Systematic Review of the Development and Validation of the Heat Vulnerability Index: Major Factors, Methods, and Spatial Units
Authors: Niu Yanlin , Li Zhichao , Gao Yuan , Liu Xiaobo , Xu Lei , Vardoulakis Sotiris , Yue Yujuan , Wang Jun , Liu Qiyong 
Published: April 2021

AbstractPurpose of reviewThis review aims to identify the key factors, methods, and spatial units used in the development and validation of the heat vulnerability index (HVI) and discuss the underlying limitations of the data and methods by evaluating the performance of the HVI.Recent findingsThirteen studies characterizing the factors of the HVI development and relating the index with validation data were identified. Five types of factors (i.e., hazard exposure, demographic characteristics, socioeconomic conditions, built environment, and underlying health) of the HVI development were identified, and the top five were social cohesion, race, and/or ethnicity, landscape, age, and economic status. The principal component analysis/factor analysis (PCA/FA) was often used in index development, and four types of spatial units (i.e., census tracts, administrative area, postal code, grid) were used for establishing the relationship between factors and the HVI. Moreover, although most studies showed that a higher HVI was often associated with the increase in health risk, the strength of the relationship was weak.SummaryThis review provides a retrospect of the major factors, methods, and spatial units used in development and validation of the HVI and helps to define the framework for future studies. In the future, more information on the hazard exposure, underlying health, governance, and protection awareness should be considered in the HVI development, and the duration and location of validation data should be strengthened to verify the reliability of HVI.
Optimization of Hydrogen Generation by Catalytic Hydrolysis of NaBH4 with Halloysite-Supported CoB Catalyst Using Response Surface Methodology
Authors: Hosgun Seda , Ozdemir Mine , Sahin Yeliz Buruk 
Published: April 2021

AbstractThe hydrolysis of sodium borohydride (NaBH4) is a promising reaction with a possible practical application as a means of generating hydrogen. The efficiency of hydrogen production can be enhanced significantly by use of a catalyst during the reaction. Cobalt borides show significant catalytic activity, but unsupported CoB particles aggregate easily and are difficult to separate from the reaction medium for re-use. The objectives of the present study were to use halloysite (Hly) as a support material to increase the catalytic activity and reusability of a Co metal-based system and to investigate the binary effect of metal loading and reaction parameters on the hydrolysis of NaBH4. Catalysts were prepared by wet impregnation and chemical reduction. The surface morphology and structural properties of the prepared catalysts were characterized using N2 adsorption-desorption and the Brunauer-Emmet-Teller (BET) method, field emission scanning electron microscopy (FE-SEM), with energy dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and inductively coupled plasma mass spectrometry (ICP-MS). Response surface methodology (RSM) was used to optimize metal loading and reaction conditions for the hydrogen-generation rate. Optimum reaction conditions were determined (using Design Expert 7.0 software) as 5.01 wt.% Co loading using a Co-B/Hly-supported catalyst, 0.44 M NaBH4, 10.66 mg catalyst, and at a reaction temperature of 39.96°C. The maximum hydrogen generation rate was 33,854 mL min−1 gCo−1 under these conditions.
Cerebrospinal Fluid Pleocytosis Not Attributable to Status Epilepticus in First 24 Hours
Authors: Bajaj Sargun , Griesdale Donald , Agha-Khani Yahya , Moien-Afshari Farzad 
Published: April 2021

ABSTRACT:Background:Status epilepticus (SE) has traditionally been thought to cause cerebrospinal fluid (CSF) pleocytosis. However, attributing CSF pleocytosis solely to SE without addressing the underlying etiology may lead to poor outcomes. Leukocyte recruitment to CSF has been shown to peak around 24 hours after prolonged seizures in animal studies, suggesting that CSF pleocytosis within the first 24 hours of SE onset may be due to underlying causes. The goal of this study is to assess if SE is associated with CSF pleocytosis, independent of other causes within the first 24 hours of onset.Methods:We completed a historical cohort study of adult patients with SE admitted to the intensive care unit of Vancouver General Hospital between March 2010 and May 2019.Results:Of the 441 patients admitted with SE during the study period, 107 met our inclusion criteria leading to 111 lumbar punctures (LPs), with 4 patients receiving two LPs. CSF pleocytosis was seen in 12 of 72 patients who underwent an LP within the first 24 hours of SE onset. In all 12 patients, a secondary etiology for the pleocytosis was observed aside from SE. Of the six CSF samples collected after 24 hours of onset that demonstrated pleocytosis, four had no cause for pleocytosis other than SE.Conclusions:In all 12 patients with CSF pleocytosis in the first 24 hours of onset of SE, an underlying etiology was identified. Therefore, any pleocytosis noticed within the first 24 hours of onset of refractory SE should not be attributed solely to SE.
Increased risk of leukaemia in children with Down syndrome: a somatic evolutionary view
Authors: Hasaart K. A. L. , Bertrums E. J. M. , Manders F. , Goemans B. F. , van Boxtel R. 
Published: April 2021

AbstractChildren show a higher incidence of leukaemia compared with young adolescents, yet their cells are less damaged because of their young age. Children with Down syndrome (DS) have an even higher risk of developing leukaemia during the first years of life. The presence of a constitutive trisomy of chromosome 21 (T21) in DS acts as a genetic driver for leukaemia development, however, additional oncogenic mutations are required. Therefore, T21 provides the opportunity to better understand leukaemogenesis in children. Here, we describe the increased risk of leukaemia in DS during childhood from a somatic evolutionary view. According to this idea, cancer is caused by a variation in inheritable phenotypes within cell populations that are subjected to selective forces within the tissue context. We propose a model in which the increased risk of leukaemia in DS children derives from higher rates of mutation accumulation, already present during fetal development, which is further enhanced by changes in selection dynamics within the fetal liver niche. This model could possibly be used to understand the rate-limiting steps of leukaemogenesis early in life.
Implementation of a pilot community-based psychosocial intervention for patients with psychoses in Chile and Brazil: a comparative analysis of users' perspectives
Authors: Dev Saloni , Kankan Tanvi , Blasco Drew , Le PhuongThao D. , Agrest Martin , Dishy Gabriella , Mascayano Franco , Schilling Sara , Jorquera María José , Dahl Catarina , Cavalcanti Maria Tavares , Price LeShawndra , Conover Sarah , Yang Lawrence H. , Alvarado Rubén , Susser Ezra S. 
Published: April 2021

Abstract

Background
Few studies provide clear rationale for and the reception of adaptations of evidence-based interventions. To address this gap, we describe the context-dependent adaptations in critical time intervention-task shifting (CTI-TS), a manualized recovery program for individuals with psychosis in Rio de Janeiro, Brazil and Santiago, Chile. Implications of the adaptations – incorporating a task-shifting approach and modifying the mode of community-based service delivery – are examined from users' perspectives.

Methods
A secondary analysis of in-depth interviews with CTI-TS users (n = 9 in Brazil; n = 15 in Chile) was conducted. Using the framework method, we thematically compared how participants from each site perceived the main adapted components of CTI-TS.

Results
Users of both sites appreciated the task-shifting worker pair to provide personalized, flexible, and relatable support. They wanted CTI-TS to be longer and experienced difficulty maintaining intervention benefits in the long-term. In Chile, stigma and a perceived professional hierarchy toward the task-shifting providers were more profound than in Brazil. Engagement with community-based services delivery in homes and neighborhoods (Chile), and at community mental health centers (Brazil) were influenced by various personal, familial, financial, and social factors. Uniquely, community violence was a significant barrier to engagement in Brazil.

Conclusion
CTI-TS’ major adaptations were informed by the distinct mental health systems and social context of Santiago and Rio. Evaluation of user experiences with these adaptations provides insights into implementing and scaling-up task-shifting and community-oriented interventions in the region through the creation of specialized roles for the worker pair, targeting sustained intervention effects, and addressing socio-cultural barriers.
Policy Dialogue: The Rise and Decline of Catholic Education, 1500-Present
Authors: Grendler Paul , MacGregor Carol Ann 
Published: April 2021

AbstractCatholic schools have faced a number of hurdles in recent decades, including the sharp decline of vocations among religious sisters who have worked in schools (as much as 90 percent in the last four decades), rising tuition prices for families, the sexual abuse crisis, and questions about institutional commitment to maintaining schools in light of these challenges. These changes affect all students and families, but have special significance for those of lower socioeconomic status, who historically used Catholic schools as an engine of upward mobility.For this policy dialogue, the editors of HEQ asked Paul Grendler and Carol Ann MacGregor to reflect on the benefits, challenges, and turning points of Catholic-sponsored education from the sixteenth century to the present. Grendler is Professor Emeritus of History at the University of Toronto, the former president of the Renaissance Society of America and the American Catholic Historical Association, and a recipient of the Galileo Galilei Prize. The author of eleven books, he has published widely on education in the Renaissance. His recent work concentrates on Jesuit universities and Jesuit schools, especially in Italy. MacGregor is Associate Professor of Sociology and current Vice Provost at Loyola University New Orleans. She has also been named an Associate Fellow of the Institute for Advanced Studies in Culture at the University of Virginia. Her publications, which have appeared in American Catholic Studies and American Sociological Review (among others), focus on Catholic education policy and practice, and religion and public life.HEQ Policy Dialogues are, by design, intended to promote an informal, free exchange of ideas between scholars. At the end of the exchange, we offer a list of references to readers who wish to follow up on sources relevant to the discussion.
Women's Education and Literacy in England, 1066–1540
Authors: Hall Megan J. 
Published: April 2021

AbstractThis essay provides a holistic review of what girls and young women learned, and the settings in which they learned, in the Middle Ages in England between the Norman Conquest (1066) and the Dissolution of the Monasteries (late 1530s). Education of girls was carried out in households, elementary schools, and nunneries, as well as through employment and apprenticeship. Girls were taught a wide range of subjects, depending on their socioeconomic status, including practical skills, reading comprehension, and social accomplishments. This essay also provides a review to date of the scholarship on the topic.
A Duchess “given to contemplation”: The Education of Margaret Cavendish
Authors: Spencer E Mariah 
Published: April 2021

AbstractMargaret Cavendish was an unusually public figure in early modern England. She published widely under her own name on several secular subjects, including natural philosophy, inequality of the sexes, and educational theory. This article explores the development of Cavendish's educational theories through a detailed account of her life, which took place in three discrete stages. First, it examines her youth, when she was informally educated by family members and private tutors. It then follows her education as she traveled to Europe with her embattled queen and met her husband, William Cavendish. And finally, it shows that with William's support and patronage, Cavendish returned to England at the Restoration as a confident and mature female author. In doing so, this article addresses questions related to Cavendish's pedagogical beliefs, why those beliefs sometimes differed from her own experiences, and how she communicated these ideas through her literature.
Twitch user perceptions, attitudes and behaviours in relation to food and beverage marketing on Twitch compared with YouTube
Authors: Pollack Catherine C. , Gilbert-Diamond Diane , Emond Jennifer A. , Eschholz Alec , Evans Rebecca K. , Boyland Emma J. , Masterson Travis D. 
Published: April 2021

Abstract
Influencer marketing may be amplified on livestreaming platforms (e.g., Twitch) compared with asynchronous social media (e.g., YouTube). However, food and beverage marketing on Twitch has not been evaluated at a user level. The present study aimed to compare users’ self-reported exposure to food marketing and associated attitudes, consumption and purchasing behaviours on Twitch compared with YouTube. A survey administered via social media was completed by 621 Twitch users (90 % male, 64 % white, 69 % under 25 years old). Of respondents, 72 % recalled observing at least one food or beverage advertisement on Twitch. There were significant differences in the recall of specific brands advertised on Twitch (P < 0⋅01). After observing advertised products, 14 % reported craving the product and 8 % reported purchasing one. In chat rooms, 56 % observed conversations related to food and 25 % participated in such conversations. There were significant differences in the number of users who consumed various products while watching Twitch (P < 0⋅01). Of users who frequented YouTube (n 273), 65 % reported negative emotions when encountering advertising on YouTube compared with 40 % on Twitch (P < 0⋅01). A higher proportion felt Twitch's advertising primarily supported content creators (79 v. 54 %, P < 0⋅01), while a higher proportion felt that YouTube's advertising primarily supported the platform (49 v. 66 %, P < 0⋅01). The findings support that food marketing exposures on Twitch are noticeable, less bothersome to users and influence consumption and purchasing behaviours. Future studies are needed to examine how the livestreaming environment may enhance advertising effectiveness relative to asynchronous platforms.
Persistent level of mental distress in PTSD patients is not reflected in cytokine levels 1 year after the treatment
Authors: Toft Helge , Bramness Jørgen , Tilden Terje , Bolstad Ingeborg , Lien Lars 
Published: April 2021

AbstractObjective:Cross-sectional data show that post-traumatic stress disorder (PTSD) patients often have increased levels of circulating inflammatory markers. There is, however, still a paucity of longitudinal studies with long follow-up times on levels of cytokines in such patients. The current study assesses patients with and without PTSD diagnosis 1 year after discharge from inpatient treatment.Methods:Patients in treatment for serious non-psychotic mental disorders were recruited at the beginning of their treatment stay at a psychiatric centre in Norway. Ninety patients submitted serum samples and filled out the Hopkins Symptom Checklist-90 Revised Global Severity Index (HSCL-90R GSI) questionnaire during their mainstay and at a follow-up stay 1 year after discharge. Of these patients, 33 were diagnosed with PTSD, 48 with anxiety, depression, or eating disorder, while 9 patients had missing data. The patients were diagnosed using the Mini-International Neuropsychiatric Interview (MINI).Results:At the follow-up stay (T3), PTSD patients had higher levels of GSI scores than non-PTSD patients (p = 0.048). These levels were unchanged from the year before (T2) in both groups. The levels of circulating cytokines/chemokine did not differ between the PTSD and non-PTSD patients at T3. At T2, however, the PTSD and non-PTSD groups exhibited different levels of interleukin 1β (IL-1β) (p = 0.053), IL-1RA (p = 0.042), and TNF-α (p = 0.037), with the PTSD patients having the higher levels.Conclusion:Despite exhibiting different mental distress scores, the PTSD and non-PTSD patients did not differ regarding levels of circulating inflammatory markers at 1-year follow-up.
The effects of different temperatures of post-exercise protein-containing drink on gastric motility and energy intake in healthy young men
Authors: Fujihira Kyoko , Hamada Yuka , Haramura Miki , Suzuki Katsuhiko , Miyashita Masashi 
Published: April 2021

AbstractThe present study examined the effects of different temperatures of protein-containing drink after exercise on subsequent gastric motility and energy intake in healthy young men. Twelve healthy young men completed three, 1-d trials in a random order. In all trials, the subjects ran on a treadmill for 30 min at 80% of maximum heart rate. In exercise + cold drink (2°C) and exercise + hot drink (60°C) trials, the subjects consumed 300 ml of protein-containing drink (0·34 MJ) at 2°C or 60°C over a 5-min period after exercise. In the exercise (i.e. no preload) trial, the subjects sat on a chair for 5 min after exercise. Then, the subjects sat on a chair for 30 min to measure their gastric motility with an ultrasound imaging system in all trials. Thereafter, the subjects consumed a test meal until they felt comfortably full. Energy intake in the exercise + hot drink trial was 14 % and 15 % higher than the exercise (P = 0·046, 95% CI 4·010, 482·538) trial and exercise + cold drink (P = 0·001, 95% CI 160·089, 517·111) trial, respectively. The frequency of the gastric contractions in the exercise + hot drink trial was higher than the exercise (P = 0·023) trial and exercise + cold drink (P = 0·007) trial. The total frequency of gastric contractions was positively related to energy intake (r = 0·386, P = 0·022). These findings demonstrate that consuming protein-containing drink after exercise at 60°C increases energy intake and that this increase may be related to the modulation of the gastric motility.
The Cuyano proto-ocean between the Chilenia and Cuyania terranes: rifting and plume interaction during the Neoproterozoic – early Palaeozoic evolution of the SW Gondwana margin
Authors: Pérez Luján Sofía B. , Boedo Florencia L. , Ariza Juan P. , Vujovich Graciela I. , Alvarado Patricia , Kay Suzanne M. 
Published: April 2021

AbstractThe Precordillera mafic–ultramafic belt (PMUB), located in central-western Argentina, comprises mafic and ultramafic bodies interlayered and/or in tectonic contact with marine siliciclastic units. Whole-rock, mineral geochemistry and Nd–Sr isotope analyses performed in magmatic rocks suggest a relatively different spatial and temporal evolution along the belt. The southern PMUB (south of 32° S) evolved as an intra-continental rifted margin with an enriched mid-ocean-ridge basalt (E-MORB) tholeiitic to alkaline magmatism, to a proto-ocean basin (the Cuyano proto-ocean) with tholeiitic normal-MORB geochemical signature. Based on neodymium model ages (TDM), the magmatic activity started during the late Neoproterozoic Era and continued into the early Palaeozoic Era. Instead, the northern PMUB (28–32° S) evolved as an intra-continental rifted margin with dominant tholeiitic E-MORB to continental flood basalt (CFB) magmatism during the early Palaeozoic Era. ϵNd values (+3.4 to +8.4), rare earth element trends and high-field-strength element systematics, together with an estimated potential mantle temperature of c. 50–100°C above ambient mantle, suggest the PMUB magmatism derived from an enriched mantle source related to the effect of a rising plume linked to the Iapetus Ocean opening. In particular, TDM estimations of 600–550 Ma agree with reported magmatism in central to southern Appalachians. The magmatism in the PMUB, and those registered in the Neoproterozoic Catoctin Formation and in the Southern Oklahoma Aulacogen in the conjugated Laurentian margin, seem to be contemporaneous, sharing a similar plume-enriched mantle source. In this context, the E-MORB signature identified along the PMUB can be described as a plume-distal ridge tectonic setting over an extended margin.
Sources of information about gestational weight gain, diet and exercise among Brazilian immigrant women living in the USA: a cross-sectional study
Authors: Lindsay Ana Cristina , Le Qun , Nogueira Denise L , Machado Márcia MT , Greaney Mary L 
Published: April 2021

AbstractObjective:The objective of this study was to assess sources of information about gestational weight gain (GWG), diet and exercise among first-time pregnant Brazilian women in the USA.Design:Cross-sectional survey.Setting:Massachusetts, USA.Participants:First-time pregnant Brazilian women.Results:Eighty-six women, the majority of whom were immigrants (96·5 %) classified as having low acculturation levels (68 %), participated in the study. Approximately two-thirds of respondents had sought information about GWG (72·1 %), diet (79·1 %) and exercise (74·4 %) via the internet. Women classified as having low acculturation levels were more likely to seek information about GWG via the internet (OR = 7·55; 95 % CI 1·41, 40·26) than those with high acculturation levels after adjusting for age and receiving information about GWG from healthcare provider (doctor or midwife). Moreover, many respondents reported seeking information about GWG (67 %), diet (71 %) and exercise (52 %) from family and friends. Women who self-identified as being overweight pre-pregnancy were less likely to seek information about diet (OR = 0·32; 95 % CI 0·11, 0·93) and exercise (OR = 0·33; 95 % CI 0·11, 0·96) from family and friends than those who self-identified being normal-weight pre-pregnancy.Conclusions:This is the first study to assess sources of information about GWG, diet and exercise among pregnant Brazilian immigrants in the USA. Findings have implications for the design of interventions and suggest the potential of mHealth intervention as low-cost, easy access option for delivering culturally and linguistically tailored evidence-based information about GWG incorporating behavioural change practices to this growing immigrant group.
A useful and simple tool to evaluate and compare the intake of total dietary polyphenols in different populations
Authors: Hinojosa-Nogueira Daniel , Pérez-Burillo Sergio , García-Rincón Inés , Rufián-Henares José A , Pastoriza Silvia 
Published: April 2021

AbstractObjective:Polyphenols are antioxidant compounds with an impact on different health factors. Thus, it is important to have precise tools to estimate the intake of polyphenols. This study focuses on the development of an intuitive tool to estimating the intake of dietary total polyphenols.Design:The tool was developed in a spreadsheet to improve accessibility and use. It is divided into six different meals for each of the 7 d with a similar format to 24-h diet recalls. The total polyphenol values of 302 foods were included and the possibility of own values.Setting:Framework of the European project Stance4Health, Granada, Spain.Participants:This tool was tested on 90 participants in different stages of life (girls, women and pregnant women). Ages ranged from 10 to 35 years.Results:The total polyphenol intake obtained was of 1790 ± 629 mg polyphenols/d. The highest consumption of polyphenols was observed in pregnant women (2064 mg/d). Polyphenols intake during the weekend was lower for the three groups compared to the days of the week. The results were comparable with those of other studies.Conclusions:The current tool allows the estimation of the total intake of polyphenols in the diet in a fast and easy way. The tool will be used as a basis for a future mobile application.