bluuebunny/crossref_metadata_2025_split huggingface dataset:
Observational study on dietary changes of participants following a multicomponent lifestyle program (Reverse Diabetes2 Now)
Authors: Pot Gerda K. , de Jong Hanne B. T. , Battjes‐Fries Marieke C. E. , Patijn Olga N. , Pijl Hanno , Voshol Peter J. 
Published: December 2021

AbstractBackgroundLifestyle intervention studies to treat type 2 diabetes (T2D) are on the rise. However, in‐depth research is lacking into the dietary changes that participants make.MethodsThe present study aimed to observe the dietary intake of participants following the group program ‘Reverse Diabetes2 Now’ (RD2N) over 12 months. The web‐based 24‐h dietary recall‐tool Compl‐eat was used to collect dietary intake data.ResultsIn total, 147 T2D patients were included in a cross‐sectional study (n = 37 at baseline, n = 58 at 6 months, n = 52 at 12 months). A lower intake of total energy, carbohydrates and iodine was found for the groups at 6 and 12 months compared to the baseline group. The absolute consumption of total fat and saturated fat did not differ between the groups; only the percentage as total calorie consumption decreased. Consumption of vegetables and full‐fat yoghurt was higher in groups at 6 and 12 months compared to the group at baseline. Consumption of bread, cakes and sweet biscuits, pasta/rice/tortillas, artificially sweetened soft drinks, and crisps were lower in the groups at 6 and 12 months compared to the group at baseline. Similar results were observed in a separate prospective study in 22 participants over 12 months following the same lifestyle‐intervention.ConclusionsOverall, participants shifted their dietary intake somewhat towards a healthier dietary pattern with overall lower energy and carbohydrates and more vegetables. Moreover, participants largely maintained this healthier pattern over 12 months. There were some concerns regarding iodine intake. These promising results need to be confirmed in a fully‐scaled study, as well in a comparison with controls.
Nurses’ mental health from early COVID‐19 pandemic to vaccination
Authors: Kim Son Chae , Rankin Larry , Ferguson Jennifer 
Published: December 2021

AbstractAimsThe influence of the COVID‐19 vaccine and the evolution of the pandemic over time on nurses’ mental health have not been thoroughly examined. This study aimed to explore the changes in nurses’ mental health from the early pandemic to the early vaccination period over a 1‐year time span and examine vaccination and coping mechanisms as predictors of nurses’ poor mental health and burnout.MethodsThree cross‐sectional surveys were conducted: Early‐pandemic (n = 320), pre‐vaccination (n = 228), and early‐vaccination cohorts (n = 292).FindingsAbout 72% of nurses in the early‐vaccination cohort were fully vaccinated with two doses of mRNA COVID‐19 vaccines. There were significant decreases in moderate/severe anxiety and moderate/severe depression for the early‐vaccination cohort compared to the other cohorts. In multivariate analyses, vaccination had almost three‐fold higher odds of moderate/severe anxiety (Odds Ratio [OR] = 2.87; 95% Confidence Interval [CI] = 1.28–6.44). High resilience, family functioning, and spirituality were associated with two‐ to five‐fold lower odds of poor mental health and burnout.ConclusionsAlthough nurses in the early‐vaccination cohort had lower anxiety and depression than earlier cohorts, COVID‐19 vaccination had minimal associations with nurses’ mental health. Coping mechanisms and organizational support appear to be important predictors of nurses’ poor mental health and burnout.Clinical relevanceThe evidence gathered over 1 year of the pandemic may be helpful for a better understanding of the challenges facing frontline nurses and preparing for future healthcare crises. As a part of the preparedness plan for the future, evidence‐based interventions that raise frontline nurses’ resilience, as well as family and spiritual support, should be considered.
My Song is Love Unknown: Liturgical Music and Rational Faith
Authors: Stacey Gregory R. P. 
Published: December 2021

AbstractWhilst philosophers have argued that musical experience provides evidence for theism, their discussions often fail to consider the aesthetic properties which give musical experience its distinctive character, or ways in which musical experience might support the beliefs of particular religious traditions. This paper begins to remedy this omission by examining how attention to liturgical music can provide rational support for Christian faith. I first explore music's emotional nature and impact, and its ability to embody Christian narratives and doctrines. In light of this discussion, I then introduce two probabilistic arguments for the truth of Christian orthodoxy, arguing that liturgical music can provide distinctive evidence for their premises.
Is OLP potentially malignant? A clue from ZNF582 methylation
Authors: Chiu Yu‐Wei , Su Yee‐Fun , Yang Cheng‐Chieh , Liu Chung‐Ji , Chen Yi‐Ju , Cheng Han‐Chieh , Wu Cheng‐Hsien , Chen Pei‐Yin , Lee Yu‐Hsien , Chen Yen‐Lin , Chen Yi‐Tzu , Peng Chih‐Yu , Lu Ming‐Yi , Yu Chuan‐Hang , Kao Shou‐Yen , Fwu Chyng‐Wen , Huang Yu‐Feng 
Published: December 2021

AbstractObjectiveWhether oral lichen planus (OLP) was potentially malignant remains controversial. Here, we examined associations of ZNF582 methylation (ZNF582m) with OLP lesions, dysplastic features and squamous cell carcinoma (OSCC).Materials and MethodsThis is a case–control study. ZNF582m was evaluated in both lesion and adjacent normal sites of 42 dysplasia, 90 OSCC and 43 OLP patients, whereas ZNF582m was evaluated only in one mucosal site of 45 normal controls. High‐risk habits affecting ZNF582m such as betel nut chewing and cigarette smoking were also compared in those groups.ResultsOLP lesions showed significantly lower ZNF582m than those of dysplasia and OSCC. At adjacent normal mucosa, ZNF582m increased from patients of OLP, dysplasia, to OSCC. In addition, ZNF582m at adjacent normal sites in OLP patients was comparable to normal mucosa in control group. Dysplasia/OSCC patients with high‐risk habits exhibited significantly higher ZNF582m than those without high‐risk habits. However, ZNF582m in OLP patients was not affected by those high‐risk habits.ConclusionsOLP is unlikely to be potentially malignant based on ZNF582m levels. ZNF582m may also be a potential biomarker for distinguishing OLP from true dysplastic features and OSCC, and for monitoring the malignant transformation of OLP, potentially malignant disorders with dysplastic features and OSCC.
Conditional impacts of political and fiscal factors on state environmental budgets
Authors: Duggan Andrew R. , Carr Douglas A. , Yan Wenli 
Published: December 2021

AbstractMaintaining fiscal responsiveness to deteriorating environmental conditions is a critical concern for civil society and public managers. Drawing from multiple theoretical perspectives and panel data of state environmental agency appropriations, we add to the budgeting literature on this salient topic with an examination of the legal, political, institutional, and fiscal factors that drive, and condition, environmental budgets. Given the influence of environmental pollution on funding—as stressed by previous literature—we offer evidence that such impacts are moderated by business interests, political party control in government, and fiscal capacity. Findings from this investigation provide insights into fiscal responsiveness and environmental governance at the state level, which can help elucidate and guide other federal and state co‐funded programs.
Immigrant status, race, and voter turnout in the American mass public
Authors: Qi Dan , Gonzalez Sylvia 
Published: December 2021

AbstractObjectiveThis study examines the joint effects of immigrant generation and race on voter turnout.MethodsUsing data from the 2018 Cooperative Congressional Election Study, this study compares voter turnout across immigrant generations across different racial groups.ResultsOur analysis shows that turnout rates in the 2018 midterm election are higher for blacks and Latinos as they become further removed from their immigration generation. Immigration generation has no effect on the turnout for Asians and other race respondents, and for whites, we find that voter turnout is highest among third‐generation immigrants.ConclusionOur findings generally support our expectations but there are differences across racial groups.
An outbreak of SARS‐CoV‐2 on a transplant unit in the early vaccination era
Authors: Roberts Scott C. , Foppiano Palacios Carlo , Grubaugh Nathan D. , Alpert Tara , Ott Isabel M. , Breban Mallery I. ,   Yale SARS‐CoV‐2 Genomic Surveillance Initiative, Martinello Richard A. , Smith Cindy , Davis Matthew W. , Mcmanus Dayna , Tirmizi Samad , Topal Jeffrey E. , Azar Marwan M. , Malinis Maricar 
Published: December 2021

AbstractBackgroundSolid organ transplant recipients are at increased risk of COVID‐19‐associated morbidity and mortality.AimsWe describe a nosocomial outbreak investigation on an immunocompromised inpatient unit.MethodsPatients positive for SARS‐CoV‐2 were identified. An epidemiologic investigation was assisted with whole genome sequencing of positive samples.ResultsTwo patients were identified as potential index cases; one presented with diarrhea and was initially not isolated, and the other developed hypoxemia on hospital day 18 before testing positive. Following identification of a SARS‐CoV‐2 cluster, the unit was closed and all patients and staff received surveillance testing revealing eight additional positive patients and staff members. Whole genome sequencing confirmed an outbreak. Enhanced infection prevention practices mitigated further spread. Asymptomatic patients with COVID‐19 were successfully treated with bamlanivimab.DiscussionPreventing SARS‐CoV‐2 outbreaks in transplant units poses unique challenges as patients may have atypical presentations of COVID‐19. Immunocompromised patients who test positive for SARS‐CoV‐2 while asymptomatic may benefit from monoclonal antibody therapy to prevent disease progression. All hospital staff members working with immunocompromised patients should be promptly encouraged to follow infection prevention behaviors and receive SARS‐CoV‐2 vaccination.ConclusionSARS‐CoV‐2 outbreaks on immunocompromised units can be mitigated through prompt identification of cases and robust infection prevention practices.
THE CONVERGENCE OF SCIENCE AND RELIGION
Authors: Fowler Charles W. 
Published: December 2021

AbstractMany natural patterns are obvious. We observe them in the weather, our physiology, the solar system, and our habits. We see that every finite thing is made up of parts and every finite thing is a part of something else. Relationships and characteristics occur in patterns. We see structure and function everywhere we look; everything falls into categories. Some patterns are not so well‐defined, including the function of our minds—thoughts, beliefs, emotions, opinions, and worldviews. Even so, patterns exist in the ways our minds influence what we are and do. Changing our thinking changes everything. This article is based on the premise that carefully chosen patterns provide holistic guidance. Furthermore, thinking that seeks and follows such guidance is essential—but it is ominously absent from today's world. The case is made that rectifying this situation involves conceptual consistency that matches reality/truth and the convergence of all belief systems.
Biomechanical and Anthropometric Factors That Differentiate National- and Regional-Level Judo Players
Authors: Teixeira Felipe Guimarães , Rosa Paulo Tadeu Cardozo Ribeiro , Mello Roger Gomes Tavares , Nadal Jurandir 
Published: December 2021

Purpose: The study aimed to identify the variables that differentiate judo athletes at national and regional levels. Multivariable analysis was applied to biomechanical, anthropometric, and Special Judo Fitness Test (SJFT) data. Method: Forty-two male judo athletes from 2 competitive groups (14 national and 28 state levels) performed the following measurements and tests: (1) skinfold thickness, (2) circumference, (3) bone width, (4) longitudinal length, (5) stabilometric tests, (6) dynamometric tests, and (7) SJFT. The variables with significant differences in the Wilcoxon rank-sum test were used in stepwise logistic regression to select those that better separate the groups. The authors considered models with a maximum of 3 variables to avoid overfitting. They used 7-fold cross validation to calculate optimism-corrected measures of model performance. Results: The 3 variables that best differentiated the groups were the epicondylar humerus width, the total number of throws on the SJFT, and the stabilometric mean velocity of the center of pressure in the mediolateral direction. The area under the receiver-operating-characteristic curve for the model (based on 7-fold cross validation) was 0.95. Conclusion: This study suggests that a reduced set of anthropometric, biomechanical, and SJFT variables can differentiate judo athlete’s levels.
Reliability Evaluation of Augmented Cubes on Degree
Authors: Zhang Mingzu , Yang Xiaoli , He Xiaomin , Qin Zhuangyan , Ma Yongling 
Published: December 2021

The [Formula: see text]-dimensional augmented cube [Formula: see text], proposed by Choudum and Sunitha in 2002, is one of the most famous interconnection networks of the distributed parallel system. Reliability evaluation of underlying topological structures is vital for fault tolerance analysis of this system. As one of the most extensively studied parameters, the [Formula: see text]-conditional edge-connectivity of a connected graph [Formula: see text], [Formula: see text], is defined as the minimum number of the cardinality of the edge-cut of [Formula: see text], if exists, whose removal disconnects this graph and keeps each component of [Formula: see text] having minimum degree at least [Formula: see text]. Let [Formula: see text], [Formula: see text] and [Formula: see text] be three integers, where [Formula: see text], if [Formula: see text] and [Formula: see text], if [Formula: see text]. In this paper, we determine the exact value of the [Formula: see text]-conditional edge-connectivity of [Formula: see text], [Formula: see text] for each positive integer [Formula: see text] and [Formula: see text], and give an affirmative answer to Shinde and Borse’s corresponding conjecture on this topic in [On edge-fault tolerance in augmented cubes, J. Interconnection Netw. 20(4) (2020), DOI:10.1142/S0219265920500139 ].
Analysis of Lens Thickness Distribution Based on Swept-Source Optical Coherence Tomography (SS-OCT)
Authors: Feng Xi , Wang Yong , Liang Jianheng , Xu Yali , Ortega-Usobiaga Julio , Cao Danmin 
Published: December 2021

Objective. This study aimed to analyze the distribution of lens thickness (LT) and its associations in age-related cataract patients based on swept-source optical coherence tomography (SS-OCT). Methods. This cross-sectional study included 59,726 Chinese age-related cataract patients. Only right-eye data were included in the study. Repeated measures of ocular parameters were performed using an IOL Master 700 device. The distributions of ocular biometric data including anterior chamber depth (ACD), LT, axial length (AL), central corneal thickness (CCT), white-to-white (WTW), and mean keratometry (MK) and their associations with age were assessed. The anterior segment (AS) was measured as the sum of CCT, ACD, and LT, while the vitreous chamber depth (VCD) was calculated as the difference between AL and AS. The values of LT : AL, AS : AL, and VCD : AL in different AL groups and their changes are the main outcome measures used to observe the proportion of the anterior and posterior segments of the eye. Results. Biometric data were available for 59,726 individuals. The mean age was 68.81 years (range = 40–100); 40.62% were male and 59.38% were female. Mean anterior chamber depth (ACD) was 3.02 ± 0.44 mm, mean LT was 4.51 ± 0.44 mm, mean axial length (AL) was 23.89 ± 1.92 mm, mean central corneal thickness (CCT) was 0.53 ± 0.03 mm, mean white-to-white (WTW) was 11.64 ± 0.44 mm, and mean keratometry (MK) was 44.27 ± 1.65 diopter. Female patients had shorter AL, shallower ACD, smaller CCT and WTW, decreased LT, and steeper corneas (

p

< 0.005). ACD revealed the strongest negative correlation (

p

≤ 0.001, r = –0.682) with LT. Age (

p

≤ 0.001, r = 0.348) showed a moderate positive correlation, whereas MK (

p

＜ 0.05, r = 0.011), CCT (

p

≤ 0.001, r = 0.041) had a weak positive correlation and WTW (

p

≤ 0.001, r = –0.034) had a weak negative correlation with LT. A nonlinear correlation was found between LT and AL. LT increased with age in both males and females. LT changed variably in eyes with AL less than 27 mm, LT decreased as AL increased, then LT gradually increased as AL increased in extremely long and extra-long eyes (

p

≤ 0.001). LT : AL and AS : AL decreased as AL increased, VCD : AL gradually increased as AL increased in highly myopic eyes, and VCD : AL increased by about 0.01 for every 1 mm increase in AL. Conclusions. Among Chinese age-related cataract patients, we found LT to have the strongest relation with ACD. The lens was thicker in elderly patients and women. The correlation between LT and AL is not a simple negative correlation; with the increase of age, LT decreases first and then increases. The proportion of VCD is constantly rising with the elongation of AL.
On Certain Bounds for Edge Metric Dimension of Zero-Divisor Graphs Associated with Rings
Authors: Siddiqui Hafiz Muahmmad Afzal , Mujahid Ammar , Binyamin Muhammad Ahsan , Nadeem Muhammad Faisal 
Published: December 2021

Given a finite commutative unital ring

S

having some non-zero elements

x
,

y

such that

x
.
y
=
0

, the elements of

S

that possess such property are called the zero divisors, denoted by

Z

S

. We can associate a graph to

S

with the help of zero-divisor set

Z

S

, denoted by

ζ

S

(called the zero-divisor graph), to study the algebraic properties of the ring

S

. In this research work, we aim to produce some general bounds for the edge version of metric dimension regarding zero-divisor graphs of

S

. To do so, we will discuss the zero-divisor graphs for the ring of integers

ℤ

m

modulo

m

, some quotient polynomial rings, and the ring of Gaussian integers

ℤ

m

i

modulo

m

. Then, we prove the general result for the bounds of edge metric dimension of zero-divisor graphs in terms of maximum degree and diameter of

ζ

S

. In the end, we provide the commutative rings with the same metric dimension, edge metric dimension, and upper dimension.
Imaging High-Risk Atherothrombosis Using a Novel Fibrin-Binding Positron Emission Tomography Probe
Authors: Izquierdo-Garcia David , Diyabalanage Himashinie , Ramsay Ian A. , Rotile Nicholas J. , Mauskapf Adam , Choi Ji-Kyung , Witzel Thomas , Humblet Valerie , Jaffer Farouc A. , Brownell Anna-Liisa , Tawakol Ahmed , Catana Ciprian , Conrad Mark F. , Caravan Peter , Ay Ilknur 
Published: December 2021

Background and Purpose:
High-risk atherosclerosis is an underlying cause of cardiovascular events, yet identifying the specific patient population at immediate risk is still challenging. Here, we used a rabbit model of atherosclerotic plaque rupture and human carotid endarterectomy specimens to describe the potential of molecular fibrin imaging as a tool to identify thrombotic plaques.

Methods:

Atherosclerotic plaques in rabbits were induced using a high-cholesterol diet and aortic balloon injury (N=13). Pharmacological triggering was used in a group of rabbits (n=9) to induce plaque disruption. Animals were grouped into thrombotic and nonthrombotic plaque groups based on gross pathology (gold standard). All animals were injected with a novel fibrin-specific probe
68
Ga-CM246 followed by positron emission tomography (PET)/magnetic resonance imaging 90 minutes later.
68
Ga-CM246 was quantified on the PET images using tissue-to-background (back muscle) ratios and standardized uptake value.

Results:

Both tissue-to-background (back muscle) ratios and standardized uptake value were significantly higher in the thrombotic versus nonthrombotic group (
P
<0.05). Ex vivo PET and autoradiography of the abdominal aorta correlated positively with in vivo PET measurements. Plaque disruption identified by
68
Ga-CM246 PET agreed with gross pathology assessment (85%). In ex vivo surgical specimens obtained from patients undergoing elective carotid endarterectomy (N=12),
68
Ga-CM246 showed significantly higher binding to carotid plaques compared to a D-cysteine nonbinding control probe.

Conclusions:

We demonstrated that molecular fibrin PET imaging using
68
Ga-CM246 could be a useful tool to diagnose experimental and clinical atherothrombosis. Based on our initial results using human carotid plaque specimens, in vivo molecular imaging studies are warranted to test
68
Ga-CM246 PET as a tool to stratify risk in atherosclerotic patients.
General Anesthesia Versus Conscious Sedation for Mechanical Thrombectomy in Acute Anterior Circulation Ischemic Stroke
Authors: Zhang Liqun , Dinsmore Judith , Khan Usman , Leyon Joe , Ogungbemi Ayokunle , Trippier Sarah , Clarke Brian , Luong Chan , Campbell Rebecca , Clifton Andrew , Cluckie Gillian , Elwishi Mazen 
Published: December 2021

Background
Retrospective studies suggested that general anesthesia (GA) for mechanical thrombectomy has worse outcomes compared with conscious sedation (CS). However, randomized single‐center trials suggested noninferiority of GA to CS. We investigated the impact of anesthesia techniques on thrombectomy, and hypothesized that the routine use of GA with a defined protocol would not adversely affect thrombectomy delivery or outcomes.

Methods
A total of 451 consecutive patients receiving mechanical thrombectomy for anterior circulation ischemic stroke from 2016 to 2019 were identified from the local registry. Patients were divided into cohort A when both GA and CS were used, and cohort B (from October 2017) when GA became the default method. Favorable functional outcome was defined as modified Rankin scale of 0 to 2 at 3 months. Intraprocedural blood pressures were audited annually.

Results

In cohort A, compared with patients receiving CS, patients with GA had prolonged median arrival to arterial puncture time (26 versus 18 minutes;
P
<0.001) and comparable favorable functional outcome at 3 months (37.7% versus 45.1%;
P
=0.355). In cohort B, the median arrival to arterial puncture was reduced to 10 minutes, with comparable favorable functional outcome of 46.7%, and reduced mortality compared with cohort A (14.2% versus 22.7%;
P
=0.024). Yearly audits demonstrated good adherence to the protocol. Binary logistic regression analysis showed only old age (odds ratio [OR], 1.04; 95% CI, 1.02–1.07 [
P
=0.003]), high National Institute of Health Stroke Scale at presentation (OR, 1.17; 95% CI, 1.08–1.26 [
P
<0.001]), and poor collateral status (OR, 0.29; 95% CI, 0.12–0.72 [
P
=0.008]) were independent factors predicting for poor prognosis, not GA (OR, 0.71; 95% CI, 0.32–1.60 [
P
=0.408]).

Conclusions
Patients treated under GA for mechanical thrombectomy achieved comparable functional outcome at 3 months compared with those under CS. Through practice and a defined protocol, GA for mechanical thrombectomy can achieve sustainable good functional outcomes. Large clinical trials are needed to confirm these findings.