bluuebunny/crossref_metadata_2025_split huggingface dataset:
Corporate social responsibility in the luxury sector: The role of moral foundations
Authors: Hang Haiming , Rodrigo Padmali , Ghaffari Mahsa 
Published: August 2021

AbstractThe academic literature on whether consumers respond positively toward corporate social responsibility (hereafter CSR) initiatives in the luxury sector is limited and contradictory. Our research contributes to this on‐going debate by exploring the role of CSR moral foundations. By differentiating individualizing moral foundations (e.g., justice) from binding moral foundations (e.g., loyalty), our three experiments jointly suggest consumers respond more positive toward CSR guided by binding (vs. individualizing) foundations. Our results further suggest perceptions of intrinsic CSR motives mediate the impact of CSR moral foundations on consumer attitude. However, this mediation is moderated by the nature of tourism destination, more evident in a nature‐based (vs. urban) destination. Taken together, our research suggests the luxury sector needs to focus on binding foundations rather than individualizing foundations to create a win‐win situation.
Macrovasculature and positron emission tomography (PET) standardized uptake value in patients with lung cancer
Authors: Pu Jiantao , Leader Joseph K. , Zhang Dongning , Beeche Cameron A. , Sechrist Jacob , Pennathur Arjun , Villaruz Liza C. , Wilson David 
Published: August 2021

AbstractPurposeTo investigate the relationship between macrovasculature features and the standardized uptake value (SUV) of positron emission tomography (PET), which is a surrogate for the metabolic activity of a lung tumor.MethodsWe retrospectively analyzed a cohort of 90 lung cancer patients who had both chest CT and PET‐CT examinations before receiving cancer treatment. The SUVs in the medical reports were used. We quantified three macrovasculature features depicted on CT images (i.e., vessel number, vessel volume, and vessel tortuosity) and several tumor features (i.e., volume, maximum diameter, mean diameter, surface area, and density). Tumor size (e.g., volume) was used as a covariate to adjust for possible confounding factors. Backward stepwise multiple regression analysis was performed to develop a model for predicting PET SUV from the relevant image features. The Bonferroni correction was used for multiple comparisons.ResultsPET SUV was positively correlated with vessel volume (R = 0.44, p < 0.001) and vessel number (R = 0.44, p < 0.001) but not with vessel tortuosity (R = 0.124, p > 0.05). After adjusting for tumor size, PET SUV was significantly correlated with vessel tortuosity (R = 0.299, p = 0.004) and vessel number (R = 0.224, p = 0.035), but only marginally correlated with vessel volume (R = 0.187, p = 0.079). The multiple regression model showed a performance with an R‐Squared of 0.391 and an adjusted R‐Squared of 0.355 (p < 0.001).ConclusionsOur investigations demonstrate the potential relationship between macrovasculature and PET SUV and suggest the possibility of inferring the metabolic activity of a lung tumor from chest CT images.
Incorporating Hydrophobic Cellulose Nanocrystals inside Latex Particles via Mini‐Emulsion Polymerization
Authors: Pakdel Amir Saeid , Cranston Emily D. , Dubé Marc A. 
Published: August 2021

AbstractHydrophobic cellulose nanocrystals (CNCs) are encapsulated inside poly(butyl acrylate/vinyl acetate/acrylic acid) latex particles via mini‐emulsion polymerization (MEP). To achieve a genuine MEP, the effects of the concentration of surfactants (sodium dodecyl sulfate/Disponil A3065) and a hydrophobic agent (octadecyl acrylate (ODA)) are optimized in the presence of 0.5 wt% CNC. Using a combination of surfactant and ODA concentrations leading to a particle nucleation method restricted to the monomer droplets, the effects of CNC loading up to 1.5 wt% on the polymerization process and final nanocomposite properties are studied. Despite an increase in particle size and a lower rate of polymerization at higher CNC loadings, the droplet nucleation mechanism remains dominant up to 1.25 wt% CNC loading. Pressure‐sensitive adhesive (PSA) performance for nanocomposites produced using hydrophobic CNCs in MEP decreases whereas performance improves considerably when using hydrophilic and partially hydrophobic CNCs in conventional emulsion polymerization. These results shed light on emulsion polymerization technique selection and CNC surface properties for greener industrial production of water‐based PSAs.
Role of chemical exchange on the relayed nuclear Overhauser enhancement signal in saturation transfer MRI
Authors: Jin Tao , Kim Seong‐Gi 
Published: August 2021

PurposeThe pH sensitivity of chemical exchange‐relayed nuclear Overhauser enhancement (rNOE) signal in a saturation transfer experiment is not fully understood and needs further investigation.MethodsA three‐pool‐exchange model was simulated assuming that the magnetization transfer between an NOE pool and water is relayed by a chemical exchange (CE) pool. The saturation transfer signals from bovine serum albumin (BSA) and egg white albumin (EWA) phantoms were measured with different pH or different D2O/H2O mixture solutions.ResultsSimulation results showed that the rNOE signal is independent of the Larmor frequency of the CE pool, indicating any CE pool can effectively relay NOE magnetization. The rNOE signal is sensitive to a change of the CE pool size and/or exchange rate only if the CE becomes a rate‐limiting step in the relay process. The rNOE signal from BSA phantoms showed larger pH‐dependence at −3.0 ppm than those at −1.9 and −4.0 ppm. However, rNOE signals from aliphatic protons have much weaker pH‐dependence than the CEST signal, suggesting that CE is unlikely the rate‐limiting step and the rNOE signals in BSA are mainly relayed by fast exchanging protons. The existence of aromatic NOE was confirmed by proton spectroscopy.ConclusionThe pH‐sensitivity of the rNOE signal is determined by whether the CE process is a rate‐limiting step in the relay. The rNOE signal has much weaker pH‐sensitivity than the CEST signal in BSA proteins, which can explain the weak pH sensitivity of rNOE in vivo.
Association between adherence to warfarin and thrombotic events in patients with antiphospholipid syndrome in Japan: A claims‐based retrospective cohort study
Authors: Byambajav Tserenlkham , Waki Takashi , Miura Katsuyuki , Tanaka‐Mizuno Sachiko 
Published: August 2021

AbstractPurposeWe aimed to evaluate adherence and persistence to warfarin therapy among patients with antiphospholipid syndrome (APS) and investigate the association between adherence and thrombotic events in those patients.MethodsWe conducted a retrospective cohort study using the Japan Medical Data Center claims database from 2005 to 2018. Patients with APS receiving warfarin treatment were included in this study. Adherence and persistence were evaluated using the proportion of days covered (PDS) and refill gap methods, respectively. Demographic characteristics of patients were obtained. Kaplan–Meier curves with log‐rank tests and Cox regression models were used to examine the association between adherence or persistence and time to thrombotic events.ResultsA total of 186 patients (mean age: 46.5 ± 12.4 years, females 68.8%) were included in this study. No significant differences were observed in risk factors for thrombosis and cardiovascular diseases among groups. Most patients were adherent (91.4%) and persistent (88.2%) to warfarin treatment. Adherent and persistent patients had a significantly higher rate of thrombotic event‐free survival than nonadherent and nonpersistent patients (p < 0.05). Multivariable Cox regression showed that the risk of thrombotic events was higher in nonadherent patients (with a hazard ratio of 3.23 [95% confidence interval CI: 1.15–9.11]) and in nonpersistent patients (with a hazard ratio of 3.45 [95% CI: 1.35–8.82]).ConclusionsIn patients with APS, nonadherence and nonpersistence to warfarin treatment was associated with a higher risk of thrombotic events, suggesting the careful monitoring of those patients.
Efficacy of mindfulness‐based stress reduction on fear of emotions and related cognitive behavioral processes in Chinese University students: A randomized controlled trial
Authors: Li Jing , Qin Xinghong 
Published: August 2021

AbstractFear of losing control over one's emotions has gained increased research interest. Mindfulness‐based stress reduction (MBSR) has been found to improve emotional disturbance in clinical and nonclinical samples. However, no studies have concurrently examined the direct effects of MBSR on reduced fear of emotions among university students in Chinese culture, as well as its indirect effects on reduced fear of emotions via improvements in the cognitive‐behavioral processes. A total of 106 college students were randomly assigned to MBSR or to a control group. Assignment to the MBSR intervention led to increases in mindfulness and decentering, and decreases in rumination, emotion regulation difficulties, Affective Control Scale (ACS)‐anger, ACS‐depression, ACS‐anxiety, ACS‐positive emotion and total ACS score, as compared to the control group. The reduction of fear of positive emotion was less than that in fear of anger, depression and anxiety. MBSR was effective to reduce the fear of emotions in college students. Moreover, college students in Chinese culture tended to have a more moderate experience of positive emotions. Attention (mindfulness) and thought (decentering and rumination) may be possible cognitive mechanisms for explaining how MBSR may reduce fear of emotions in college students. Our findings provide important information that can be applied to the design of future studies or mental health resources for reducing fear of emotions in university programs.
Examining teachers' judgment of students' 21st century skills and academic and behavioral outcomes
Authors: Woods‐Groves Suzanne , Choi Taehoon , Balint‐Langel Kinga 
Published: August 2021

AbstractIn this study we examined the relationship of students' 21st century skills with their academic and behavioral outcomes. We investigated K‐12 teachers' (n = 150) judgment of students' (n = 3,108) use of 21st century skills (i.e., persistence, curiosity, affect, and cognition behaviors) via a Likert‐type rating scale. We compared teachers' ratings with students' academic and behavioral outcomes in a southeastern school district. We used Hierarchical Linear Modeling with length of teacher acquaintance with the student as the nesting variable. Teacher ratings for students' low instances of persistence behaviors and high instances of externalizing affect behaviors were predictive of a higher probability of student office discipline referrals. We found a positive correlation for teachers' ratings of students' cognition behaviors and their reading, mathematics, and science outcomes. Teachers' student length of acquaintance was significant for academic outcomes. Results indicated a predictive relationship with teachers' judgment of students' 21st century skills and student outcomes.
A mixed‐method study of paraprofessional roles, professional development, and needs for training in elementary schools
Authors: Wiggs Nicole B. , Reddy Linda A. , Bronstein Briana , Glover Todd A. , Dudek Christopher M. , Alperin Alex 
Published: August 2021

AbstractParaprofessionals are critical school staff often responsible for students with or at risk for academic, behavioral, and social impairments. However, research on paraprofessional roles, professional development, and training needs is very limited. The present mixed‐method study seeks to fill this gap by examining the student populations served, paraprofessionals' reported work setting, available professional development, and training needs. In a sample of 215 paraprofessionals from 62 schools, results indicated that paraprofessionals deliver interventions and supports to individual and small groups of students, often serve students who exhibit disruptive classroom behavior, and students who are eligible for special education services. Work setting consists primarily of a single classroom (general or special education) with multiple students. Paraprofessionals reported receiving 1–2 h of workshop‐based professional development per year which is not job‐embedded in the classroom settings. Nearly all participants reported the need for additional training in one or more topic areas with behavior management strategies, the most frequently identified are of training need. Implications for practice are discussed.
CD99 and polymeric immunoglobulin receptor peptides deregulation in critical COVID‐19: A potential link to molecular pathophysiology?
Authors: Siwy Justyna , Wendt Ralph , Albalat Amaya , He Tianlin , Mischak Harald , Mullen William , Latosinska Agnieszka , Lübbert Christoph , Kalbitz Sven , Mebazaa Alexandre , Peters Björn , Stegmayr Bernd , Spasovski Goce , Wiech Thorsten , Staessen Jan A. , Wolf Johannes , Beige Joachim 
Published: August 2021

AbstractIdentification of significant changes in urinary peptides may enable improved understanding of molecular disease mechanisms. We aimed towards identifying urinary peptides associated with critical course of COVID‐19 to yield hypotheses on molecular pathophysiological mechanisms in disease development. In this multicentre prospective study urine samples of PCR‐confirmed COVID‐19 patients were collected in different centres across Europe. The urinary peptidome of 53 patients at WHO stages 6–8 and 66 at WHO stages 1–3 COVID‐19 disease was analysed using capillary electrophoresis coupled to mass spectrometry. 593 peptides were identified significantly affected by disease severity. These peptides were compared with changes associated with kidney disease or heart failure. Similarities with kidney disease were observed, indicating comparable molecular mechanisms. In contrast, convincing similarity to heart failure could not be detected. The data for the first time showed deregulation of CD99 and polymeric immunoglobulin receptor peptides and of known peptides associated with kidney disease, including collagen and alpha‐1‐antitrypsin. Peptidomic findings were in line with the pathophysiology of COVID‐19. The clinical corollary is that COVID‐19 induces specific inflammation of numerous tissues including endothelial lining. Restoring these changes, especially in CD99, PIGR and alpha‐1‐antitripsin, may represent a valid and effective therapeutic approach in COVID‐19, targeting improvement of endothelial integrity.
Water‐mediated interactions destabilize proteins
Authors: Sumi Tomonari , Imamura Hiroshi 
Published: August 2021

AbstractProteins are folded to avoid exposure of the nonpolar groups to water because water‐mediated interactions between nonpolar groups are a promising factor in the thermodynamic stabilities of proteins—which is a well‐accepted view as one of the unique effects of hydrophobic interactions. This article poses a critical question for this classical view by conducting an accurate solvation free‐energy calculation for a thermodynamic cycle of a protein folding using a liquid‐state density functional theory. Here, the solvation‐free energy for a leucine zipper formation was examined in the coiled‐coil protein GCN4‐p1, a typical model for hydrophobic interactions, which demonstrated that water‐mediated interactions were unfavorable for the association of nonpolar groups in the native state, while the dispersion forces between them were, instead, responsible for the association. Furthermore, the present analysis well predicted the isolated helical state stabilized by pressure, which was previously observed in an experiment. We reviewed the problems in the classical concept and semiempirical presumption that the energetic cost of the hydration of nonpolar groups is a driving force of folding.
Gamma‐irradiation of common biological samples for stable carbon and nitrogen isotope and elemental analyses
Authors: Gorman Daniel , Skrzypek Grzegorz , McLaughlin M. James , Bearham Douglas , Vanderklift Mathew A. 
Published: August 2021

RationaleAround the world biosecurity measures are being strengthened to prevent the spread of pests and diseases across national and international borders. Quarantine protocols that involve sample sterilisation have potential effects on sample integrity. The consequences of sterilisation methods such as gamma (γ)‐irradiation on the elemental and chemical properties of biological samples have not been widely examined.MethodsWe tested the effect of γ‐irradiation (50 kGy) on the stable carbon and nitrogen isotope compositions (δ13C and δ15N values) and elemental concentrations (C % and N %) of common biological samples (fish, plants and bulk soils). The analysis used a continuous flow system consisting of a Delta V Plus isotope ratio mass spectrometer connected with a Thermo Flash 1112 elemental analyser via a ConFlo IV interface. Results were compared using two one‐sided tests (TOST) to test for statistical similarity between paired samples.ResultsThere was no change in the δ15N values or N % of γ‐irradiated samples, and only small changes to the δ13C values of consumers (range: 0.01‰ to 0.04‰), producers (−0.02‰ to 0.04‰) and sediments (0‰ to 0.07‰). The magnitude of change in δ13C values was greatest at low carbon concentrations but appeared negligible when measured against replicated sample analysis and the combined analytical uncertainty (i.e., 0.10‰). The C % values of irradiated samples were higher for consumers (0.23%) and lower for producers and sediments (0.04% and 0.05%, respectively) which may have implications for certain types of biological material.ConclusionsRoutine γ‐irradiation has little effect on the stable carbon and nitrogen isotope compositions of common biological samples and marginal effects on carbon elemental concentrations. This is unlikely to warrant concerns since the observed difference is typically of a magnitude lower than other sources of potential uncertainty.
Finite state machine for cloud forensic readiness as a service (CFRaaS) events
Authors: Kebande Victor R. , Choo Kim‐Kwang Raymond 
Published: August 2021

AbstractThe importance of demonstrating the correctness of forensic analysis tools and automated incident management tools reinforces the need for a finite state machine (FSM) engine that can generate automated forensic processes. Hence, in this paper, we present an event‐based FSM representation for Cloud Forensic Readiness as a Service (CFRaaS), where we also show how the FSM's predetermined states and transitions could be used to formulate an automated forensic process and generate a hypothesis for litigation purposes. Specifically, this proposition comprises a two‐step level CFRaaS‐FSM with possible transitions and states. This representation is useful because it can alert digital forensic investigators on how to deduce current and next state of attacks based on transitions and current states.
Improvement of mechanical, thermal and antimicrobial properties of organically modified montmorillonite loaded polycaprolactone for food packaging
Authors: Seyrek Merve Eryılmaz , Okur Müjgan , Saraçoğlu Nurdan 
Published: August 2021

AbstractThe aim of this study is to evaluate the biodegradable packaging materials which will be an alternative to traditional synthetic packaging materials. For this purpose, packaging films containing polycaprolactone (PCL), montmorillonite (MMT), and organically modified montmorillonite (OMMT) were prepared by solution casting method, and the mechanical, physical, structural, antimicrobial, and antifungal properties of these films were examined. Cetyl trimethyl ammonium bromide (CTAB) was used for the modification of montmorillonite. The structural properties of the prepared films were characterized by attenuated total reflection‐Fourier transform infrared, X‐ray powder diffraction, thermogravimetric analysis, and scanning electron microscopy. The PCL/OMMT structure was found to be thermally more stable than the PCL/MMT structure. The addition of OMMT to PCL improved the thermal and mechanical properties of the films compared with the pure PCL and PCL/MMT films. In addition, adding MMT/OMMT to the PCL caused an increase in the hardness of the films. In the antimicrobial analysis, while no inhibition effect was observed in PCL/MMT films, PCL/OMMT films showed inhibition effect against Staphylococcus aureus. Antifungal tests performed with the prepared films showed that the film‐wrapped bread did not deteriorate for 40 days. It is thought that PCL/MMT and PCL/OMMT films prepared in this study will provide an advantage in applications as packaging material.
Use of eltrombopag and granulocyte colony‐stimulating factor in treatment of lomustine overdose in a dog
Authors: Aspinall Sophie , Desmas Isabelle , Bazelle Julien 
Published: August 2021

AbstractAn 8‐year‐old male neutered golden retriever diagnosed with a T‐cell lymphoma and treated with a modified LOPP (lomustine, vincristine, prednisolone and procarbazine) protocol was presented to a referral hospital for management of an accidental overdose of lomustine (180 mg/m2). This overdose resulted in a severe myelosuppression with neutropenia and thrombocytopenia. The human platelet stimulator eltrombopag was used as part of the treatment protocol, alongside granulocyte‐macrophage colony‐stimulating factor and supportive care. The dog made a good recovery and completed a course of chemotherapy, achieving complete clinical remission of the lymphoma and long‐term survival (613 days).
Lab‐scale continuous flow studies for comparative biosorption of cadmium (II) on untreated and xanthated Ficus religiosa biomass
Authors: Tariq Madiha , Farooq Umar , Athar Makshoof , Salman Muhammad , Tariq Muqaddas , Shahida Shabnam , Farooqi Zahoor H. 
Published: August 2021

AbstractThe present studies report the use of an ecofriendly biomass Ficus religiosa in untreated (UFR) and xanthate treated (XFR) forms for the Cd (II) ions removal in a fixed bed column. FTIR, SEM‐EDS, BET surface area, and elemental analysis (CHNS) techniques were used to characterize the biosorbents. The acquired data supported FTIR findings regarding the nature of functional groups present in the materials. Packed bed continuous flow studies explored the effects of various parameters such as Cd (II) ion concentration (100 mg/L–300 mg/L), bed heights (5 cm–30 cm), pH (3–5), at a constant linear flow rate (~1.13 cm/min). The obtained S‐shaped breakthrough curves indicated the efficiency of the packed bed for the Cd (II) removal. Breakthrough time and exhaust times increased (67.5 min–390 min and 292.5 min–1852.5 min) (97.5 min–442.5 min and 345 min–1920 min) for unmodified and modified respectively with bed heights. The BDST, Thomas, and Yoon‐Nelson models were used to evaluate the experimental results. The Yoon‐Nelson model describes the breakthrough data more efficiently compared to other models. Under similar conditions, the modified material exhibited 400% increased capacity (55.20 mg/g) than that of unmodified material (13.33 mg/g). Thus, xanthate modification significantly enhanced the capacity for Cd (II) ions from aqueous solutions.Practitioner Points

Xanthate modification of Ficus religiosa is an environmentally friendly process.
Modified and unmodified materials were utilized for Cd (II) removal in fixed bed column process which is industrially viable process.
Low inlet Cd (II) concentration at pH 5 and higher bed height favored the continuous flow process at fixed flow rate.
Modification caused an increase of about 400% in the capacity of material.