bluuebunny/crossref_metadata_2025_split huggingface dataset:
New analysis of the ρ-class bursts, known as the “heartbeat” of GRS 1915+105: Pulse profile and spectral properties
Authors: Mineo T. , Massa F. , Massaro E. , Feroci M. 
Published: April 2021

Context. We present the results of a new analysis of three long Rossi-XTE observations of the microquasar GRS 1915+105 in the ρ class, performed in 1997, 1999, and 2000, and characterized by different peak profiles. The first data set, labeled G-1, is dominated by a single peak, while in the third observation (G-3), all bursts show a clearly detectable couple of peaks. The second observation (G-2) shows an intermediate structure with a single peak and an emerging shoulder on the decay side.
Aims. We devised a new procedure to obtain mean burst profiles in every energy channel independently of the recurrence time intervals of the bursts, variable from 45 s to 53 s in the considered observations, with the aim of investigating the different features of peaks and the eventual spectral variations.
Methods. All the bursts were aligned at a common time bin on the decaying portion of the bursts that is stable in simultaneous light curves at different energies. An averaging algorithm was then applied without modifying the statistical properties or scaling the burst lengths. We analyzed the peak amplitude ratios and the dependence of their delays on energy. The spectral distributions were evaluated for the various components: a stable multi-temperature disk plus a power law Comptonization component was used for the baseline emission and temperature differences of peak components were evaluated with the inclusion of an additional blackbody.
Results. In addition to the well-observed double peak (P1 and P2) pattern, we detected a third small peak (P3) in the structured G-3 light curve. This peak, differently from the other two, exhibits a fast rising and a slower exponential decay, with a e-folding time constant of 1.32 s. The blackbody temperatures of P2 and P3 are higher than P1 and the power law spectrum of P3 is the flattest one.
Conclusions. The time and spectral behavior of P3 is interpreted as a signature of a relatively hot plasma outflow from the disk into the corona and its duration is consistent with the crossing timescale of the particles through the corona where electrons radiate.
Risikostratifizierung des NSTE-ACS
Authors: Hartung Philipp , Jobs Alexander , Thiele Holger 
Published: April 2021

ZusammenfassungMit zunehmender Verbesserung der Prognose der NSTE-ACS-Patientenkollektive in den letzten Jahren spielt eine standardisierte, schnelle und gute diskriminierende Risikostratifizierung eine erhebliche Rolle. Verschiedene Merkmale des langfristig erwartbaren ischämischen Risikos, wie z.B. klinische Parameter, EKG-Indikatoren, Biomarker und klinische Scores, werden zusammen mit dem individuellen Blutungsrisiko erfasst und integriert. So ist z.B. die absolute Höhe der Troponin-Konzentration prädiktiv für die Gesamtletalität. Der GRACE-Risk-Score wird nicht nur zusätzlich zur objektiven Risikostratifizierung empfohlen, sondern ein Punktwert >140 ist eines der Kriterien für eine frühe Koronarangiografie innerhalb von 24 Stunden. Die Abschätzung des Blutungsrisikos entsprechend der ARC-HBR-Kriterien hat einen Einfluss auf das antithrombotische Therapieregime.
Diagnosis and successful treatment of an Austrian dog infected with Trypanosoma congolense forest type
Authors: Leschnik Michael , Silbermayr Katja , Guija Abigail , Nell Barbara 
Published: April 2021

AbstractCanine African Trypanosomosis (CAT) is a rarely described disease with frequently lethal outcome. A 5-year-old female mongrel dog weighing 22 kg was presented in Austria due to unilateral uveitis, pancytopenia, and anorexia 4 months after return from a trip through Western Africa. Trypanosoma spp. flagellates were detected in a blood smear and identified as Trypanosoma congolense forest type by PCR. Initial treatment with imidocarb and miltefosine led to clinical improvement but only isometamidium chloride hydrochloride applied intramuscularly led to complete eradication of the pathogen from the dog’s blood 4 months later.
Tic-Störungen und Tourette-Syndrom
Authors: Senberg Asne , Roessner Veit 
Published: April 2021

ZUSAMMENFASSUNGTics können sehr unterschiedlich, z. B. motorischer oder vokaler Natur sein und bewegen sich auf einem Kontinuum von einfach bis komplex. Wenn nur motorische Tics oder nur vokale Tics länger als ein Jahr anhalten, wird die Diagnose einer chronischen Tic-Störung des jeweiligen Subtyps vergeben. Für die Diagnose Tourette-Syndrom müssen mindestens 2 motorische und ein vokaler Tic aufgetreten sein. Die Lebenszeitprävalenz irgendeiner chronischen Tic-Störung liegt bei ca. 4 %. Tics haben einen schwankenden Verlauf auf verschiedenen Zeitskalen, d. h. z. B. situative Schwankungen im Verlauf von Minuten bis hin zu längerfristigen Veränderungen über Jahren; so nehmen sie nach Erstauftreten meist im Kindesalter gefolgt von einem Gipfel um die Pubertät herum häufig im Laufe des Jugendalters ab. Man geht von einer multifaktoriellen Ätiologie aus, die sich aus genetischen, neurobiologischen, umweltbezogenen und psychosozialen Faktoren zusammensetzt. Tics treten häufig mit anderen psychischen Erkrankungen gemeinsam auf. Die häufigsten Begleitsymptome bis -störungen sind dabei ADHS und Zwangsstörungen. Diese Begleitsymptomatik ist oft für die Betroffenen beeinträchtigender als die Tics selbst, weshalb sie vorranging behandelt werden sollten. Wenn die Tics jedoch das Funktionsniveau des Individuums stark beeinträchtigen, sollte eine mögliche Behandlung in Betracht gezogen werden. Dabei werden meist Antipsychotika eingesetzt, die die Betroffenen zwar nicht heilen, jedoch die Tic-Ausprägung mindern. Eine spezialisierte Verhaltenstherapie ist wirksam, aber vor Ort oft nicht verfügbar.
Bladder Preservation with Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation for the Treatment of Muscle-invasive Carcinoma of the Bladder: A Single-Center Experience
Authors: Agrawal Chinmayee , Bansal Saurabh , Biswas Manoj , Gupta Meenu , Nautiyal Vipul , Ahmed Mushtaq 
Published: April 2021

Abstract
Purpose The purpose of the study was to evaluate the short-term response and acute toxicities in muscle-invasive carcinoma urinary bladder treated with neoadjuvant chemotherapy followed by concurrent chemoradiation.
Materials and Methods Thirty patients with muscle-invasive bladder cancer were treated with three cycles of neoadjuvant chemotherapy every 3 weeks. Response assessment was done after 4 weeks with repeat cystoscopy and imaging. Responders were treated with concurrent chemoradiation 60 Gy/30# at 2 Gy/# along with weekly injection cisplatin 35 mg/m2. Response assessment was done by new response evaluation criteria in solid tumors (version 1.1). Treatment-related acute toxicities were scored using common terminology criteria for adverse events version 4.0.
Results Of the 30 patients, 25 patients responded to neoadjuvant chemotherapy with complete response in 17 patients (56.67%) and partial response in eight patients (26.66%). Five patients (16.66%) showed poor response and were advised radical cystectomy, of which four underwent radical cystectomy and one patient opted for concurrent chemoradiation. Of 26 patients who completed chemoradiation, complete response was seen in 21 patients (80.76%) and partial response was seen in four patients (15.38%). Only one patient developed progression of disease in the form of lung metastasis. All the patients with residual disease were advised to undergo salvage cystectomy. Among the patients receiving chemoradiation, grade 2 cystitis and diarrhea was seen in 10 patients (38.46%) and four patients (15.38%), respectively. Only one patient developed grade 3 diarrhea.
Conclusion Bladder preservation treatment is an effective, safe, and convenient option for patients presenting with muscle-invasive carcinoma bladder. Neoadjuvant chemotherapy followed by chemoradiation was well-tolerated with an acceptable rate of complications.
Multiscale photonic imaging of the native and implanted cochlea
Authors: Keppeler Daniel , Kampshoff Christoph A. , Thirumalai Anupriya , Duque-Afonso Carlos J. , Schaeper Jannis J. , Quilitz Tabea , Töpperwien Mareike , Vogl Christian , Hessler Roland , Meyer Alexander , Salditt Tim , Moser Tobias 
Published: April 2021

Significance
For the development of gene therapy and optical cochlear implants (oCI), detailed knowledge of the cochlear morphology is crucial. Here, we employed multiscale X-ray and fluorescence imaging for quantitative assessment of scala tympani, vestibuli, and media, as well as the spiral ganglion in Rosenthal’s canal for various species commonly used in auditory research. Furthermore, we demonstrate the feasibility of oCI implantation for rodents and marmosets, as a nonhuman primate model. Using modeling of light propagation from the emitters of the oCI, we estimate the frequency selectivity and range covered by optical stimulation within the cochlea.
Cellular-resolution gene expression profiling in the neonatal marmoset brain reveals dynamic species- and region-specific differences
Authors: Kita Yoshiaki , Nishibe Hirozumi , Wang Yan , Hashikawa Tsutomu , Kikuchi Satomi S. , U Mami , Yoshida Aya C. , Yoshida Chihiro , Kawase Takashi , Ishii Shin , Skibbe Henrik , Shimogori Tomomi 
Published: April 2021

Significance
The MGA contains a large gene expression dataset from the developing brain of the common marmoset. However, the data represent the gene expression patterns across the entire brain, and methods to isolate region-specific gene expression patterns will provide important information regarding primate brain structure, function, and cellular and molecular organization. We have developed a system, GePS, that systematically identifies genes expressed in selected regions of the common marmoset brain. Comprehensive, comparative gene expression analysis with mice revealed many genes with species- and region-specific expression. Moreover, by combining GePS with the gene expression comparison and cortical area projection mapping systems, we were able to provide further insight into the molecular organization of these species- and region-specific gene expression patterns.
Precision mapping child undernutrition for nearly 600,000 inhabited census villages in India
Authors: Kim Rockli , Bijral Avleen S. , Xu Yun , Zhang Xiuyuan , Blossom Jeffrey C. , Swaminathan Akshay , King Gary , Kumar Alok , Sarwal Rakesh , Lavista Ferres Juan M. , Subramanian S. V. 
Published: April 2021

SignificanceTo the best of our knowledge, this is the first prediction of child anthropometric failure estimates for 597,121 villages—the smallest local governance unit—in India. While prior child nutrition policies and programs in India focused on districts for planning, implementation, and monitoring, we highlight that a majority of the geographic variation in child anthropometric failures occur at the micro geographic level of villages followed by the macro administrative level of states. Precision mapping of health data at the village level can enable more informed and effective local politics in India.
The Youth Engagement with Global Sustainability Inventory (YEGSI): development and validity-based studies (Inventario de Compromiso Juvenil con la Sostenibilidad: estudios de desarrollo y validez)
Authors: Moreira Paulo A. S. 
Published: April 2021

The construct of engagement has great potential for understanding adolescents’ subjective connection to/identification with global sustainability issues. However, there are currently no validated instruments for measuring young people’s engagement with global sustainability from a multidimensional psychological perspective. This study presents the Youth Engagement with Global Sustainability Inventory (YEGSI) and an assessment of its psychometric properties using a sample of 692 adolescents. An exploratory factor analysis using a random half of the sample ( n = 341) revealed five dimensions: cognitive, emotional, behavioural, school, and family. A confirmatory factor analysis using the remaining participants ( n = 351) supported modelling these factors as a correlated five-factor model. All five subscales had good reliability. Positive correlations between YEGSI dimensions and wellbeing were identified, indicating the scale had convergent validity. In sum, the YEGSI appeared to be a valid and reliable measure. This measure has the potential to develop research and practice in the domain of engagement with sustainability.
Chaos physics: what to teach in three lessons?
Authors: Tél Tamás 
Published: April 2021

Abstract
Chaotic phenomena are not part of standard curricula, although this subject offers several interesting aspects which can help students better understand basic features of science. A central observation is that even simple physical systems, if chaotic, are unpredictable, just like the weather. We present the principles applied when developing a freely available short interactive material and outline the material itself. By the means of this material students can become acquainted with the elements of chaos science and also learn that the regular motions taught in physics lessons are the exceptions rather than the rule since a slight modification of the set-up (e.g. letting the suspension point of a pendulum move periodically) converts the motion to chaotic. The material can be used in both classroom and online teaching.
Tsunami-induced inundation on the coast of Palu City
Authors: Alam R R R , Adityawan M B , Farid M , Chrysanti A , Widyaningtias  , Kusuma M A 
Published: April 2021

Abstract
The frequency of tsunamis in Indonesia is smaller than other natural disasters. But its destructive power is quite large. Although this disaster has a low probability of occurring. The losses caused by these disaster equaled and even exceeded frequent disasters such as floods and landslides. More than 85% of tsunamis in Indonesia were caused by underwater earthquakes. Thus, mitigation efforts are needed to minimize the impact of the tsunami disaster. The source of the tsunami wave was generated on the Makassar Strait Thrust North Fault. In this study, tsunami was modelled by using Delft3D software. The model approach uses the principle of momentum and continuity. The area of the model was divided into 2 grids. The wave reached the bay mouth in 10 minutes and arrived at the coast of the study area in 20 minutes. The highest peak of water level on the coast occurred in the second wave with an amplitude of 2.45 m and a wave height of 5.19 m. The inundation map was compared to the recorded data from the 2018 tsunami. It was found that there is no significant difference between the two although the tsunami generation were different.
Seismic assessment of irregularities in steel special moment resisting frame with asymmetric-plan building (case study: Gedung D - Universitas Dharma Andalas)
Authors: Fitrah R A , Mazni D I , Pratiwi W , Jauhari Z A 
Published: April 2021

Abstract
The limitation of land is becoming the issue where the symmetric-plan building could not always be the proper choice. Besides that, the demands of architectural and esthetical construction also quickly increase. Then, there is the possibility where asymmetric-plan building will be the choice, in this case Gedung-D Universitas Dharma Andalas. But, designing asymmetric-plan building is having obstacle where the past studies revealed that the damage under strong ground motion become the major problem. It is because the asymmetric-plan will lead excessive torsion due to the horizontal irregularities or soft-story issue due to vertical irregularities. Then, it certainly affects the stability of structure. This research conducted the seismic assessment of asymmetric-plan 5-story building where Gedung-D Universitas Dharma Andalas, Padang will take place. The assessment is conducted by modeling three dimensional steel special moment resisting frame with seismic design category-D. Equivalent lateral force is applied to obtain early identification and response spectrum analysis is used in the next procedure to fulfill additional requirements. Based on SNI 1726:2019, the building has been categorized as horizontal irregularities where torsional irregularities and re-entrant corner irregularities mostly happened. It indicates that the other additional requirements need to be reconsidered such as increasing the design force about 25%, the amplified accidental torsions, P-? effect. In the other hand, vertical irregularities do not act toward this building. However, there are some inadequate values of inter-story drifts in X-direction toward drift limit. Then, it is concluded that this asymmetric-plan multi-story building needs to be designed in lateral resistance if this will be planned in future and act the good seismic performance.
Flood hydrograph simulation to estimate peak discharge in Ciliwung river basin
Authors: Pratama M I , Rohmat F I W , Farid M , Adityawan M B , Kuntoro A A , Moe I R 
Published: April 2021

Abstract
Ciliwung River Basin is one of 13 watersheds located in the Special Capital Region of Jakarta (DKI Jakarta), one of the most vulnerable cities facing flood disaster. Modeling hydrographs in a flood computer model is a crucial process in understanding the hydraulic processes in floods; however, more often than have adequately not studied watersheds do not available observed data. Well-calibrated hydrographs serve as the basis for a basin-wide flood model. In this study, the Snyder, ITB, and SCS Unit Hydrograph are constructed in the study case of flooding in the Ciliwung River Basin, with West Java rainfall distribution method and Alternating Block Method as the adopted rainfall distributions, providing six combinations of approaches. Calibration and validation analysis show a combination of West Java rainfall distribution and SCS UH with a lag time of 5.5 gives the smallest deviation, with an accuracy of 83.3%, therefore it is recommended for use to estimate design future flood hydrograph.
The effect of dem resolution on calculation of erosion in Batang Kuranji watershed
Authors: Herdianto R , Syofyan E R , Istijono B 
Published: April 2021

Abstract
Batang Kuranji Watershed with a total area of Watershed 224.7 km2 comprises Batang Sungai Sapiah Sub-watershed, Batang Danau Limau Manih Sub-watershed, Batang Sungkai Sub-watershed, Batang Bukik Tindawan Sub-watershed and Batang Padang Janiah Sub-watershed. Batang Kuranji flows from upstream of the Bukit Barisan with the highest elevation of 1,605 meters above sea level at the peak of Bukit Tinjau Laut and empties into the Padang beach with a main river length of ± 32.41 km. DEM has an influence on the results of land erosion by affecting the slope accuracy. The higher the DEM resolution, the more precise the results of the soil erosion simulation. With the MUSLE method the rate of erosion occurs in the Batang Kuranji watershed, with DEM data of 8m and land cover in 2017, an erosion rate of 23.91 tons / hectare / year is classified in hazard class II (light), DEM data of 30m erosion rate is 7. 70 tons / hectare / year are classified in hazard class I (very mild), with DEM data of 90m erosion rate of 4.54 tons / hectare / year classified in hazard I class (very light). It can be seen that the higher the DEM resolution, the more accurate the erosion rate calculation in the watershed.
The bayesian model of Covid-19 case fatality rate proportion on provinces in Indonesia
Authors: Devianto D , Afifah A N , Febrianti I K 
Published: April 2021

Abstract
The Covid-19 pandemic has spread to all parts of Indonesia with different case fatality rates (CFR) between regions. The estimating parameter of the proportion of people who die compared to the number of people who test positive for coronavirus (parameter of CFR) can be determined using the Bayesian method approach. The estimation parameter of CFR is performed by using prior beta distribution, and the results have good performance with a high degree of accuracy. The choice of Bayesian model that can be built is a fixed effect model where the proportion of case deaths in each province is assumed to be mutually independent. Still, the movement of people between regions continues to occur so that a random effect model is more rational to be applied where the proportion of case deaths for each province is assumed to be the same as estimating parameter of CFR which is smaller than the current condition of Indonesia. The estimation parameter results of the CFR parameters are expected to be achieved by the Indonesian government by implementing Covid-19 controls system for each province as a mitigation diseases strategy.
Utilization of volcanic ashes for geopolymer based on alkaline activator and solid-liquid ratio
Authors: Ilham D J , Anggarini U , Juniarti J , Fiantis D 
Published: April 2021

Abstract
The volcanic ashes are an abundant natural resource in Indonesia, but they are still little is used optimally, such as geopolymer raw material. Geopolymers are a class of inorganic polymer that be able by the reaction of an aluminosilicate material with an alkaline solution. The research aims to investigate the synthesis of geopolymers using two types of volcanic ash (Mt. Merapi and Mt. Sinabung). The synthesis of geopolymer was carried out at variation of solid/liquid ratio at 65% : 35% and 70% : 30%, with two alkaline solutions (NaOH and KOH) under different alkaline concentration (8, 9, and 12 M). A multi-analytical approach is proposed: chemical (XRF) and spectroscopic (FT-IR) analyses. The Results showed that geopolymer is influenced by volcanic ash-type and SiO2/Al2O3 ratio. Geopolymers are formed when volcanic ash of Sinabung mix with NaOH 10 NaOH with ratio of 65% : 35%, and the polymers are relatively stable. The FTIR spectra of the synthesized geopolymers showed broad absorbance bands, between wave 972-962 cm−1 and 931-976 cm−1 assigned to the internal vibrations of Si–O–Si, and Si–O–Al respectively. Both volcanic ash materials from the Merapi and Sinabung volcanoes can be utilized for making geopolymer, suitable for both engineering and agriculture applications.
Early detection of the distribution of heat stress hazards for sustainable land use planning In Padang City
Authors: Driptufany D M , Fajrin  
Published: April 2021

Abstract
The focus of this research is to analyze the spatial distribution of heat hazards caused by urban heat island (UHI) events over a 10-year observation period. Land surface temperature in 2007 is extracted from Landsat 7 ETM + to convert the value of Digital Number (DN) on the band 6 into radiance. Land surface temperatures in 2013 and 2017 were extracted from Landsat 8 OLI / TIRS imagery with the initial step of the Digital Number (DN) band 10 being converted to spectral radiance. As for the analysis of the heat stress hazard area is done by connecting the land surface temperature with the Universal Thermal Climate Index value. The Universal Thermal Climate Index from 2007 to 2017 shows that the city’s heat stress is increasing every year in observation, where in 2007 the heat stress was in the range of moderate heat stress (2,960.87 Ha). Whereas for 2013 the heat stress increased to strong heat stress reaching 34.35 ° C with an area of 77.50 Ha. In contrast to 2013, in 2017 strong heat stress increased significantly to 2,100.81 Ha where heat stress reached a peak of 35.92ºC which is spread in almost all districts with concentrations close to the city center in addition to dense residential areas as well seen in industrial areas (semen padang), this change is in line with the development of the city area.