bluuebunny/crossref_metadata_2025_split huggingface dataset:
Music Therapy for Children With Autistic Spectrum Disorder and/or Other Neurodevelopmental Disorders: A Systematic Review
Authors: Mayer-Benarous Hanna , Benarous Xavier , Vonthron François , Cohen David 
Published: April 2021

Background: Several studies have reported contradictory results regarding the benefits of music interventions in children and adolescents with neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD).Methods: We performed a systematic review according to the PRISMA guidelines. We searched the Cochrane, PubMed and Medline databases from January 1970 to September 2020 to review all empirical findings, except case reports, measuring the effect of music therapy on youths with ASD, intellectual disability (ID), communication disorder (CD), developmental coordination disorder (DCD), specific learning disorder, and attention/deficit hyperactivity disorder (ADHD).Results: Thirty-nine studies (N = 1,774 participants) were included in this review (ASD: n = 22; ID: n = 7; CD and dyslexia: n = 5; DCD: n = 0; ADHD: n = 5 studies). Two main music therapies were used: educational music therapy and improvisational music therapy. A positive effect of educational music therapy on patients with ASD was reported in most controlled studies (6/7), particularly in terms of speech production. A positive effect of improvisational music therapy was reported in most controlled studies (6/8), particularly in terms of social functioning. The subgroup of patients with both ASD and ID had a higher response rate. Data are lacking for children with other NDDs, although preliminary evidence appears encouraging for educational music therapy in children with dyslexia.Discussion: Improvisational music therapy in children with NDDs appears relevant for individuals with both ASD and ID. More research should be encouraged to explore whether oral and written language skills may improve after educational music therapy, as preliminary data are encouraging.
Discordance in ER, PR, HER2, and Ki-67 Expression Between Primary and Recurrent/Metastatic Lesions in Patients with Primary Early Stage Breast Cancer and the Clinical Significance: Retrospective Analysis of 75 Cases
Authors: Peng Li , Zhang Zhen , Zhao Dachun , Zhao Jialin , Mao Feng , Sun Qiang 
Published: April 2021

Background: The objective was to explore the discordance in the expression of the estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki-67 between primary and recurrent/metastatic lesions in patients with early stage breast cancer as well as the prognostic impact.Method: Patients with early-stage primary breast cancer and confirmed recurrence/metastasis at Peking Union Medical College Hospital between January 2005 and August 2018 were screened. The details of discordance in each parameter between primary and recurrent/metastatic lesions and progression were recorded. Regression and survival analysis were applied to determine the association and clinical impact of the discordance.Results: We evaluated 75 patients. The discordance rate of ER, PR, HER2, and Ki-67 expression was 9.3, 14.7, 14.7, and 21.5%, respectively. Additionally, 66.7, 11.8, 14.3, and 0% of patients with Luminal A, Luminal B, HER2, and triple-negative primary tumors presented with a different subtype for the recurrent/metastatic tumors, respectively. No statistical difference in progression-free survival was observed according to the subtype of the recurrent or metastatic breast cancer (p &gt; 0.05). Among 69 patients for whom treatment was adjusted after recurrence or metastasis, 66 patients remained recurrence-free during the follow-up period.Conclusion: For patients with early-stage breast cancer, the ER, PR, HER2, and Ki-67 expression profile for recurrent/metastatic tumors does not always match that of the primary tumor. After adjusting treatment according to the receptor expression in recurrent/metastatic lesions, most patients remained progression-free during the follow-up period.
The status of a Deputy in the system of the state and municipal positions
Authors: Gutorova Alla 
Published: April 2021

The article defines the constitutional and legal status of deputies in relation to the system of the state and municipal positions. The Deputy’s mandate gives a Deputy the opportunity to act as a representative of the people, as well as a representative of the authorities. Accordingly, within the framework of constitutional and legal regulation, it is necessary to analyze and compare the term «position» with such terms as «post», «institution» and «deputy position». In the article, the author used formal-legal and comparative methods, which allowed revealing the differences in these terms, disadvantages in the constitutional legal regulation of the position of Deputy in
the system of the state positions. As a consequence of the analysis, the author comes to the conclusion that the terms «deputy position», «post», «institution» are identical. Also the author identifies the differences in the terms such as « position of Deputy» and «deputy position». As a result of the election, the candidate gets the position of Deputy, which, in its turn, gives him the opportunity to be elected to the deputy position. At the same time it is not legislatively defined the place of a member of the Federation Council, Deputy of the State Duma, Deputy of the Supreme body of the Executive or Legislature of the Federation’s subject in the system of the public
posts. It is necessary to reorganize the internal structure of the legislative authorities to exclude «superior positions» as much as possible, thereby guaranteeing the equality of deputies’ status. However, at the constituent entities, deputies should have the opportunity to influence on the formation of the Executive bodies of the subject of the Russian Federation.
Ações de enfermagem na atenção ao portador de feridas na atenção básica em saúde
Authors: Pereira de Oliveira Millena Rebeca , Queiroz de Lima Luan José , Santos Dutra Carla Rayanne , Dos Santos Maria Eduarda , Santos Silva Maria Eduarda , Pereira Silva Ester , Lopes Oliveira Diego Augusto 
Published: April 2021

Objetivo: Descrever as ações do enfermeiro no atendimento ao portador de feridas na atenção básica em saúde. Metodologia: Revisão integrativa da literatura estruturada em seis etapas que buscou responder a questão norteadora: “Quais as ações desenvolvidas pelo enfermeiro no cuidado ao portador de feridas na atenção básica em saúde?” a partir da busca de artigos de livre acesso nas bases de dados publicados no intervalo dos últimos 10 anos (2009-2019), baseado em critérios de elegibilidade estabelecidos e a partir do nível de evidência das publicações. Resultados: Os estudos incluídos para análise apontam a atuação do enfermeiro centrada na garantia e manutenção de espaço físico em conformidade com as normas sanitárias, na educação em saúde como ação de promoção da autonomia e autocuidado e na observação dos aspectos sociais e culturais do usuário no contexto da melhoria da cicatrização das lesões. Conclusões: Entende-se como necessária a inserção deste profissional enquanto participante ativo da assistência para desenvolvimento de ações embasadas no conhecimento científico e a possibilidade da redução do tempo de tratamento do usuário e na redução dos custos da assistência junto ao sistema de saúde.
The Late-time Radio Behavior of Gamma-ray Burst Afterglows: Testing the Standard Model
Authors: Kangas Tuomas , Fruchter Andrew S. 
Published: April 2021

Abstract
We examine a sample of 21 gamma-ray burst (GRB) afterglow light curves at radio frequencies and compare them to the X-ray and/or optical properties of the afterglows and to the predictions of the standard jet/fireball model. Our sample includes every Swift GRB with an X-ray light curve indicating a jet break and with a published radio light curve, as well as several other targets with observed X-ray or and/optical jet breaks. We examine the late-time decline of each burst and attempt to fit an analytical model based on the standard GRB afterglow equations to each data set. We show that most of the events in our Swift GRB sample are incompatible with the radio light-curve behavior predicted by conventional afterglow theory. Many exhibit a late-time radio decline incompatible with the post-break X-ray or optical afterglow. Only one radio afterglow in this sample, at any time, shows the eventually expected decline of ∼t
−2, although two others show it in their millimeter light curve. Several others remain consistent with the standard model if such a decline began after the observations. The radio behavior alone does not, however, indicate whether a GRB can be fit by our modeling code. Indeed, several of the well-fit GRBs may only appear so due to a lack of multiwavelength data. While a second source of emission can account for some of the anomalous radio behavior, our tests indicate this is often not the case unless the main jet component is simultaneously suppressed.
L’effet bébé et ses manifestations dans l’intersubjectivité du couple... pour le meilleur ou le pire
Authors: Ditner Dominique 
Published: April 2021

À partir d’une étude de cas issue de la clinique de la dépression postpartum parentale, l’article met en lumière les enjeux de « l’effet bébé » sur l’intrapsychique de la mère et du père mais aussi sur l’intersubjectivité active au sein du couple. La naissance de l’enfant réel et la « renaissance » de l’enfant en soi pour le père et la mère exposent le couple au surgissement de l’histoire infantile et bébé de chacun, avec le risque de la réactivation d’événements traumatiques ou névrotiques. On observe alors dans la dynamique du couple une intersubjectivité qui s’organise à partir de mouvements d’intrication ou de mise en conflit, voire de désintrication, des subjectivités respectives, un peu à l’image de la rythmicité de l’intersubjectivité primaire, pour « le meilleur ou le pire » de leur parentalité ou/et de leur conjugalité.
Infertilité secondaire et libre réalisation de l’arbre généalogique ou comment explorer les enjeux de la filiation et du désir d’enfant chez la femme gabonaise
Authors: Koumba Carelle Vanessa , Veuillet-Combier Claudine 
Published: April 2021

L’article interroge, à travers une vignette clinique, le désir d’enfant et l’infertilité secondaire en étant à l’écoute des enjeux inconscients et des représentations socioculturelles gabonaises. Il repère comment le recours à l’ amp n’exclut pas l’adhésion aux croyances traditionnelles de la malédiction. La recherche s’appuie sur une méthodologie qualitative et intègre la libre réalisation de l’arbre généalogique. L’utilisation de la médiation projective permet d’investiguer les liens familiaux, conjugaux et la place fantasmatique de l’enfant dans l’espace généalogique. L’analyse souligne, sur le plan intrapsychique, une conflictualité œdipienne non résolue. Elle pointe le passage obligé par la maternité pour accéder à un statut social valorisé soutien de l’identité féminine.
La parentification au sein des séparations parentales conflictuelles. Le cas de Marie
Authors: Arnaudeau Sophie , Berdoulat Émilie 
Published: April 2021

Au sein des séparations parentales conflictuelles, l’enfant peut adopter un rôle de parent. La parentification est une conséquence fréquente de ces situations. L’article présente le cas clinique d’une jeune fille de 12 ans illustrant l’articulation entre sa situation familiale et le phénomène de parentification. Marie est prise en charge en centre-médico-psychologique suite à une injonction de soin émise par le juge des enfants. Au sein de la séparation conflictuelle de ses parents, elle apparaît comme la soignante et la confidente de sa mère. Elle cherche à aider cette dernière par divers moyens tels que le soutien moral, le rejet du père ou encore la rupture de liens avec sa famille. Des programmes éducatifs mandatés par les tribunaux, des programmes de prévention ou des discussions avec les parents dans les écoles sembleraient pertinents afin de diminuer la parentification.
Pratiques par téléphone au temps du COVID. Une écoute sur le fil
Authors: Leca Herminie , Bécache Ève 
Published: April 2021

La crise sanitaire liée à la COVID a exigé des remaniements dans nos pratiques. Le premier confinement a été vécu par tous comme une expérience partageable, contrairement à cette deuxième période de confinement qui soulève d’autres difficultés au plan social. Ces événements sociétaux interfèrent dans nos rencontres cliniques, notamment celles par téléphone auprès d’adolescents. Le dispositif téléphone s’ajoute aux éléments à considérer dans la création du lien. Nous proposerons une réflexion sur les modalités d’écoute particulière qu’impose cette pratique à partir de deux expériences croisées celle de psychologue répondante au sein d’une ligne téléphonique hospitalière, et celle d’une pédopsychiatre dans le cadre de suivis psychothérapeutiques. Quelle est la place de l’objet téléphone dans la relation clinique, objet de dépendance rassurante, objet familier et objet transitionnel qui participe à la cocréation d’un espace transitionnel ? Comment écoutons-nous en l’absence de la rencontre corporelle?
Use of cribriform amplatzer septal occluder in the pediatric population
Authors: Pradhan Priya , Jain Sneha , Sen Supratim , Dalvi Bharat 
Published: April 2021

Purpose :
Fenestrated atrial septal defects (F-ASDs) in the pediatric population pose a challenge for transcatheter device closure since multiple devices are not preferred in small hearts. Oversizing the Amplatzer Septal Occluder (ASO) to cover the surrounding fenestrations usually distorts the central waist as well as the disc profile and often defeats the purpose. This is a retrospective observational study with an aim to assess the feasibility and safety of cribriform ASO in closing F-ASDs in small children.

Methods:
Sixteen children with F-ASD who underwent device closure with cribriform ASO were included in the study. The fenestrated septal length (FSL) and the total septal length (TSL) were measured on transesophageal echocardiogram. A device size which was 1.5–2 times the FSL but smaller than the TSL was selected. The defect was closed with a device passed through a relatively centrally placed smaller fenestration.

Results:
The median age of the cohort was 5 years (2.5–10.5). Majority (14/16) required 25 or 30 mm cribriform ASO. Aneurysmal interatrial septum was seen in most of our patients (11/15). All the patients had successful device implantation. Complete closure of the defect was seen in 11 patients while 5 patients had insignificant residual shunt at a median follow-up of 40 months (1–60 months). There were no other complications.

Conclusions:
Cribriform ASO can be used safely and effectively in closing F-ASDs in children. Deployment of the device through a small central hole allows covering maximum fenestrations and gives more stability to the device. Residual shunts, although not infrequent, are insignificant.
Überlegungen zu diskursiven Praxen über östliches Europa und deutschsprachige Minderheiten im slowenischen Raum
Authors: Krevs Birk Uršula 
Published: April 2021

Im östlichen Raum als einem Areal, wo über Jahrhunderte hinweg Migrationsbewegungen und Mehrsprachigkeit bestimmend waren, nahm die deutsche Sprache eine bedeutende Rolle wahr – sei es als Kontaktsprache in diversen dynamischen Konstellationen zu koexistenten (Nachbar-)Sprachen oder als Sprache unterschiedlicher deutschsprachiger Siedlergruppen. Hierbei erweist sich das Syntagma östliches Europa als Deiktikon, was u. a. durch mehrere Übersetzungsäquivalente im Slowenischen offensichtlich ist. Das im östlichen Europa polyfunktionale Deutsch – als historisch bedingte dominante Sprache im Habsburgerreich und gegenwärtig interregionale Sprache mit Vermittlungsfunktion – bezieht diesen Status durch seine konstitutive Teilhabe am mitteleuropäischen Sprachareal, zu dessen Kontaktareal Altösterreich, die österreichische Standardvarietät und das Ungarische, Tschechische, Slowakische, das Polnische und Slowenische wie auch das Kroatische, das im ehemaligen Gebiet der österreichisch-ungarischen Monarchie gesprochene Serbische und Bosnische, das Rumänische und Ukrainische gehören. Unter diesem Aspekt überschneidet sich das östliche Europa stark mit Mitteleuropa.
Vor dem Hintergrund der mittel- und osteuropäischen Verortung des slowenischen Raums wird im Beitrag Deutsch als dominante Kontaktsprache wie auch Muttersprache diverser Siedler und ihrer Nachfahren erfasst. Im Mittelpunkt der Betrachtungen stehen dabei die Gottscheer, deren muttersprachliches Idiom allerdings stark gefährdet ist, jedoch noch gesprochen wird. Der Vergleich mit der Lage der Deutschstämmigen in Siebenbürgen (Rumänien) dient hierbei der Differenzierung soziolinguistischer Charakteristika der Sprachgemeinschaft der Gottscheer. Aus aktueller Sicht werden exemplarisch auch einige diskursive Praxen und Ziele wichtiger Akteure mit Blick auf die Gottscheer und andere deutschsprachige Gruppen in Slowenien aufgezeigt.
Impact of decalcification on antibacterial properties of eggshell against selected poultry pathogens
Authors: Balogu T.V. , Chukwueze B.C. , Okonkwo T.P. 
Published: April 2021

Background: Eggshell which is primarily composed of more than 98% calcium carbonate crystal, serves as the physical protective and active barrier structure of egg content. Recently, antimicrobial properties of eggshell are fast becoming center of interest among stakeholders of poultry industry. However, few studies have focused on the rigidity factor of calcium components of eggshell as antimicrobial agent. Thus, this study was designed to determine the effect of decalcification on the ability of eggshell to inhibit common poultry and egg bacterial pathogens.Methods: Raw eggshell denoted as calcified eggshell (CES) and decalcified eggshell (DES) were extracted and made into fine powder. Standard protocol was used for preparations of CES and DES at concentrations of 10, 5, 2.5 and 1.25 mg/ml, and their antibacterial assays on selected bacterial pathogens (Bacillus subtilis, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli and Salmonella Typhi) were performed by agar diffusion method. Gentamicin 80mg solution (CC1) and distilled water (CC2) served as controls. Data were analysed with SPSS version 20.0 and presented as mean±SD for descriptive statistics. Friedman's two-way test ANOVA was used to compare the differences in mean values between CES, DES, CC1 and CC2 at significance level of p<0.05.Results: The mean zone diameter of inhibition produced by DES (range 13–28mm) for the isolates was significantly higher (p<0.05) than that produced by CES (range 10-21mm). However, the mean zone diameter of inhibition produced by CC1 (gentamicin) (range 16-40mm) was higher than that produced by DES or CES (p<0.05). The concentrations of DES and CES have no significant antibacterial effect on B. subtilis and K. pneumoniae (p>0.05), but had inverse effect on P. aeruginosa. Overall, DES had a better inhibitory effect than CES against B. subtilis, K. pneumoniae and P. aeruginosa, but notably, neither DES nor CES had inhibitory effect on E. coli and S. Typhi.Conclusion: Poor antibacterial effect of CES may be attributed to the calcium-protein interactions within bacterial cell membrane, which hinders absorption or mobility mechanism of the antibacterial factor of the eggshell, but decalcification had significant impact on the antibacterial profile of the eggshell for some bacterial isolates. However, S. Typhi and E. coli were totally resistant to both DES and CES. Breed of eggs with minimal calcified eggshell to withstand transportation fragility, may enhance antibacterial index and shelf-life of table eggs.
Keywords: Decalcification; Antibacterial; Eggshell; Poultry; Pathogens
Roll out of a successful antimicrobial stewardship programme in Lagos University Teaching Hospital Nigeria using the Global-Point Prevalence Survey
Authors: Oshun P.O. , Roberts A.A. , Osuagwu C.S. , Akintan P.E. , Fajolu I.B. , Ola-Bello O.I. , Odukoya O.O. , Akodu B. , Okunowo A.A. , Versporten A. , Pauwels I. , Goosens H. , Busari A.A. , Olusanya A.W. , Nwaiwu O. , Temiye E.O. , Osibogun A.O. , Bode C.O. , Stewardship Committee Antimicrobial , Oduyebo O.O. 
Published: April 2021

Background: Antimicrobial resistance (AMR) has become a public health emergency with increasing rates and spread globally. Antimicrobial stewardship (AMS) has been advocated to reduce the burden of antimicrobial resistance, promote rational and appropriate use of antibiotics and improve clinical outcomes. Education and training are one of the AMS interventions to improve antimicrobial use. We present the roll out of a successful AMS programme with education and training using the Global-PPS as data collection tool to measure AMS interventions and impact.Methodology: This was a cross sectional study on the implementation of an AMS programme at the Lagos University Teaching Hospital. Global PPS was conducted in 2015 to collect baseline data which was used to identify targets for quality improvement in AMS and was repeated in 2017 and 2018 to measure impact of AMS interventions. AMS interventions included education, feedback of Global-PPS result and writing of the hospitalwide antibiotic policy based on the baseline data.Results: Out of the 746 inpatients surveyed, 476 (68.3%) had received at least one antimicrobial on the days of Global-PPS. The antimicrobial prescribing rates reduced significantly over the three time periods. In 2015, 82.5% were placed on antimicrobials, 65.5% in 2017 and 51.1% in 2018 (p<0.00001). The documentation of indication for treatment significantly improved from 53.4% in 2015 to 97.2% in 2018 (p<0.0001). Stop review date also significantly improved from 28.7% to 70.2% in 2018 (p<0.00001). Surgical prophylaxis for more than 24 hours reduced significantly from 93.3% in 2015 to 65.7% in 2018 (p=0.002) even though the prevalence was still high. The three most commonly administered antimicrobial groups were third generation cephalosporins, imidazole derivatives and quinolones. The most commonly prescribed antibiotics for surgical prophylaxis were ceftriaxone and metronidazole in 2015 and ceftriaxone in 2017.Conclusion: The use of education and training as AMS intervention in a limited resource setting clearly made impact on antimicrobial prescribing patterns in the hospital. Global-PPS is useful to set quality improvement targets and for monitoring, evaluation and surveillance of an AMS programme.
Keywords: Antibiotic, Stewardship, Resistance, Education, Global-PPS