bluuebunny/crossref_metadata_2025_split huggingface dataset:
POR CAMINHOS E ANDANÇAS INDÍGENAS (A GEOBRICOLAGEM COMO TRILHA)/Through indigenous paths and wanderings (geo-bricolage as a trail) / A través de caminos y andanzas indígenas (geobricolagem como sendero)
Authors: Goettert Jones Dari , Mota Juliana Grasiéli Bueno 
Published: March 2021

Caminhos e andanças – e seu percorrer – são possibilidades no acompanhamento de nosso fazer geografias indígenas. A proposta é combinada com a discussão de “geobricolagem”, a “forma de mundianizar” indígena (feita através do “pensamento-por-exemplo”), que se distingue da “geoengenharia” (“pensamento-por-modelo”, ocidental-capitalista). A perspectiva de caminhos e andanças, na geografia, pode se realizar pelo envolvimento profundo junto às gentes e terras indígenas, como potência para fazer brotar ondes inusitados na relação humanas/os e não humanas/os e tendo a geobricolagem (o exemplo) como um ato também político e popular. Como citar este artigo:GOETTERT, J. D.; MOTA, J. G. B. Por caminhos e andanças indígenas (a geobricolagem como trilha). Revista NERA, v. 23, n. 54, p. 303-329 , dossiê., 2020.
Construcción de las noticias vinculadas a las problemáticas de género: procesos productivos y prácticas periodísticas
Authors: García María Soledad 
Published: March 2021

El presente artículo se centra en el abordaje de las prácticas periodísticas y el proceso de producción informativa en los temas vinculados a las problemáticas de género. Para ello, parte de un estudio de caso, el femicidio de Andrea López en la provincia de La Pampa, y examina su construcción periodística en el seno de dos matutinos regionales: La Arena y El Diario de La Pampa.
A partir de este caso, la presente investigación rastrea y analiza pautas, decisiones y acciones de las y los comunicadores que -desde diversos roles- estuvieron involucrados en la construcción de la noticia.
Con el fin de conocer en profundidad dicho proceso, realizamos una serie de entrevistas a 12 informantes clave, que nos permitieron conocer el modo que se desarrollan las rutinas mediáticas en cada periódico.
Regulación de las conductas de los estudiantes en la sociedad del gerenciamiento. Un estudio en las escuelas secundarias
Authors: Cestare Ana Mariela 
Published: March 2021

Presentamos estudios realizados en el marco de una tesis de maestría cuyo interés atiende a la regulación de las conductas de los jóvenes en escuelas secundarias en contextos caracterizados por la flexibilidad y la autogestión. Se propone el análisis de legislación gestada en el marco de la nueva Ley de Educación Provincial santacruceña que promueve novedosas maneras de ser y estar en la institución, las formas en que esa propuesta es vivenciada en las escuelas y las estrategias implementadas. En este marco los regímenes de convivencia son reemplazados por acuerdos de convivencia formulados con espíritu participativo y democrático. Sostenemos como hipótesis que, fruto de los cambios que se produjeron en los últimos años, se están generando modificaciones que involucran la flexibilidad en las prácticas de regulación de las conductas.
Politización del problema de la (in)seguridad en el nivel subnacional. Un análisis de las estrategias de prevención del delito más allá de la pena en Neuquén (2004-2007)
Authors: Sancho María Dolores 
Published: March 2021

El presente trabajo se centra en las respuestas estatales al problema de la (in)seguridad y, especialmente, en las estrategias de prevención del delito más allá de la pena desarrolladas en la Provincia del Neuquén entre 2004 y 2007. Este período coincide con uno de los momentos de mayor intensificación del proceso de politización de la cuestión del delito a nivel nacional configurado a partir del secuestro y asesinato de Axel Blumberg en marzo de 2004. El malestar social generado a raíz de este hecho junto con los deseos del entonces gobernador de la provincia, Jorge Omar Sobisch, de posicionarse a nivel nacional como un “hombre duro” frente al delito, llevaron a la elaboración y puesta en marcha del Plan Integral de Seguridad, ligado fuertemente a la racionalidad política neoliberal y neoconservadora. En este sentido, el objetivo que guía el presente trabajo consiste en contribuir a la comprensión del modo en que la politización de la (in)seguridad influye en las respuestas al delito estructuradas en el nivel de la política subnacional atendiendo al caso específico de la provincia del Neuquén. Por último, el enfoque metodológico adoptado fue cualitativo, y combina técnicas de investigación documental (registros ligados a la formulación de los programas e informes de gestión elaborados por los equipos implementadores, diarios de sesiones legislativas y artículos periodísticos), con entrevistas en profundidad a los funcionarios y técnicos vinculados a su gestión.
Antiguos y nuevos pobladores: figuraciones en el proceso de evolución social ushuaiense
Authors: Tosello Natalia 
Published: March 2021

Este ensayo propone una reflexión sobre las relaciones sociales construidas en la ciudad de Ushuaia, Tierra del Fuego, Antártida e Islas del Atlántico Sur, Argentina, tomando como marco teórico principal el concepto de «figuración» de Norbert Elías.
A través de diferentes textos relacionados con la temática se plantea que en Ushuaia existe un proceso de evolución social regulado a partir de las relaciones de fuerzas de poder desarrolladas en torno a la rivalidad antiguos/nuevos pobladores. Esta característica se fundamenta principalmente en su alta movilidad poblacional.
Beneficios del estudio de caso como método de investigación para el análisis económico de procesos de transferencia tecnológica
Authors: Monasterios Claudia Sabrina 
Published: March 2021

Existen distintas interpretaciones acerca de lo que representa la transferencia tecnológica. Mientras algunos autores la entienden como un flujo unidireccional de conocimientos que se transmite de manera sistemática, otros destacan la complejidad de un fenómeno que incluye problemas de adopción, aprendizaje y apropiación, trascendiendo el mero acto de compra-venta de un equipo o paquete tecnológico. En adhesión a esta última postura, consideramos que resulta importante la comprensión de los procesos, más allá de los resultados, y la incorporación de métodos de investigación cualitativos, que permitan abordar las particularidades presentes en dichos procesos.
En este sentido, el presente trabajo busca resaltar la importancia del método de investigación basado en estudios de caso para el análisis económico de procesos de transferencia tecnológica. Por un lado, por la posibilidad de obtener información directamente de las fuentes primarias involucradas, lo cual permite conocer detalles a los cuales no sería posible acceder a través de la literatura o bases de datos. Y, por otro lado, porque habilita una mayor interiorización en la temática, valiéndose tanto de la observación directa como de entrevistas con informantes clave. Se busca así dar cuenta de un tipo de metodología que permite explorar la singularidad de un caso particular para comprender la complejidad del fenómeno más general.
PROPUESTA DE UN MODELO DE MÍNIMOS CUADRADOS ORDINARIOS PARA ESTABLECER LAS VARIABLES DETERMINANTES PARA LA ESTIMACIÓN DEL PRODUCTO INTERNO BRUTO DE PANAMÁ
Authors: Fruto de Santana Omayra 
Published: March 2021

El problema básico de la teoría del crecimiento económico es describir el comportamiento de una economía en expansión a través del tiempo. Investigadores han expuesto la importancia de las importaciones y exportaciones para el crecimiento y el desarrollo económico de los países. Se intenta analizar si Panamá, en vez de destinar tantos recursos a las restricciones en las importaciones, debería mejor fomentar, por ejemplo, las exportaciones y factores productivos que incrementen la productividad del país. Esta investigación se propone analizar y comprobar empíricamente la relación entre las exportaciones y otras variables macroeconómicas en el crecimiento económico de Panamá y experimentar con herramientas econométricas de fácil acceso en la formación a nivel de licenciatura.
LAS RAÍCES DE LOS PESCADORES EN LA FIESTA RELIGIOSA DE SAN PEDRO Y SAN PABLO
Authors: Barcia Pincay Delton 
Published: March 2021

Una de las mejores formas de conocer y comprender las raíces de cualquier cultura es participar de sus fiestas. La presente investigación propende potenciar la festividad religiosa de los manabitas de San Pedro y San Pablo en los meses de junio y julio, manifestación cultural propia de la cultura chola del perfil costero de Manabí que en conjunto con el referente turístico genera recursos económicos a las comunidades que celebran estas festividades, considerando que una festividad es por esencia un fenómeno socio cultural multiforme y por ello implica el análisis de una teoría social que complemente la investigación. Basado en el análisis del potencial turístico, se aplicó métodos de enfoques investigación de campo, documental y bibliográfico realizando entrevista y encuestas realizadas a los habitantes. De acuerdo al análisis de la información que se obtuvo, se estableció que los habitantes de la parroquia se encuentran accesible a la llegada de visitantes que deseen compartir sus festividades. La parroquia Machalilla celebra estas fiestas y al mismo tiempo promociona sus recursos naturales, lo que está impulsando la construcción del Puerto Pesquero Artesanal que genera nuevas plazas de trabajo en el sector.
Children’s Rights Education in Diverse Classrooms
Authors: Jerome Lee , Starkey Hugh 
Published: March 2021

With PISA tables, accountability, and performance management pulling educators in one direction, and the understanding that education is a social process embedded in cultural contexts, tailored to meet the needs and challenges of individuals and communities in another, it is easy to end up in seeing teachers as positioned as opponents to the ‘system’. Jerome and Starkey argue that the United Nations Convention on the Rights of the Child (UNCRC, 1989) can provide a pragmatic starting point for educators to challenge some of these unsettling trends in a way which does not set up unnecessary opposition with policy-makers.
They review the evidence from international evaluations, surveys and case studies about practice in human rights and child right education before exploring the key principles of transformative and experiential education to synthesise a robust theoretical framework that can guide the development of child rights education. They also draw out practical implications and outline a series of teaching and learning approaches that are values informed, aligned with children’s rights and focused on quality learning.
The Political Power of Visual Art
Authors: Herwitz Daniel 
Published: March 2021

Visual art has a ubiquitous political cast today. But which politics? Daniel Herwitz seeks clarity on what is meant by politics, and how we can evaluate its presumption or aspiration in contemporary art.
Drawing on the work of William Kentridge, drenched in war, violence and race and the artworld immolations of Bansky, Herwitz’s examples range from the NEA 4 and the question of offense-as-dissent, to M.F. Husain and the Hindu nationalist Indian right wing. He is interested in understanding art practices today in the light of two opposing inheritances: the avant-gardes and their politicization of the experimental art object, and apolitical 18th-century aesthetics. His historically-informed approach reveals how crucial this pair of legacies is to reading the tensions in voice and character of art today.
Driven by questions about the capacity of the visual medium to speak politically or acquire political agency , Hertwitz’s book is for anyone working in aesthetics or the art world concerned with the fate of cultural politics in a world spinning out of control, yet within reach of emancipation.
Does trastuzumab-related cardiotoxicity influence
long-term outcome in patients with HER-2 positive
breast cancer? A prospective study
Authors: Piotrowski Grzegorz , Kulig Maciej , Stasiak Arkadiusz , Stasiak Joanna , Banach Maciej 
Published: March 2021

IntroductionTrastuzumab is a monoclonal antibody directed against the
HER-2 receptor that has led, in an adjuvant setting, to higher disease-free
(DFS) and overall survival (OS) in HER-2 positive breast cancer (BC) compared with chemotherapy alone. Cardiotoxicity often results in early discontinuation of trastuzumab, which may elevate the risk of cancer recurrence or
mortality. Our study aimed to assess how early interruption or early permanent termination of adjuvant trastuzumab treatment influences DFS and OS
of patients with HER-2 positive BC.Material and methodsThis is a prospective observation of 253 women
(55 ±10 years of age) with HER-2 positive unilateral, non-metastatic BC
treated with trastuzumab in an adjuvant setting. To monitor the safety
of the treatment echocardiography was performed at baseline and every
3 months up to 12 months after the end of therapy. If cardiotoxicity developed,
trastuzumab was stopped early. Overall survival and DFS were assessed.ResultsTrastuzumab-associated cardiac complications resulting in treatment discontinuation developed in 52 (20.55%) patients. Median DFS time
was 21.1 months in the group with interruption compared with 25.7 months
in the group with full trastuzumab treatment, being significantly shorter
(HR = 2.32, 95% CI: 1.15–4.71, p = 0.0106). Two year OS in the interruption and no-interruption groups were 80.8% and 88.5%, respectively, which
were not statistically significantly different (p = 0.268). In a multivariate
regression analysis the cumulative dose of anthracycline (OR = 1.01, 95% CI:
1.00–1.01, p = 0.002) and LVEF at baseline (OR = 0.83, 95% CI: 0.70–0.99,
p = 0.0344) were independent predictors of a cardiotoxic effect.ConclusionsTrastuzumab-related cardiotoxicity resulting in early treatment
discontinuation negatively influences DFS, but does not seem to influence OS.
Risk prediction for death and end-stage renal disease does not parallel the real-life trajectory of older patients with advanced chronic kidney disease – a Romanian center experience.
Authors: Andra Nastasa , MUGUREL APETRII , Mihai Onofriescu , Ionut Nistor , Luminita Voroneanu , Hani Hussien , Adrian Covic 
Published: March 2021

IntroductionIn 2016, the European Renal Best Practice (ERBP) group published a guideline on the management of older adults with advanced chronic kidney disease (CKD). Two risk scores were highlighted: Bansal score for mortality, and Kidney Failure Risk Equation (KFRE) for estimating progression to end-stage kidney disease (ESRD). Our group, as part of the ERBP team, aimed to apply these risk prediction tools in a cohort of older adults with eGFR <45 ml/min/1.73 m2.Material and methodsThis retrospective study included adults aged ≥65 years with CKD stage 3b-4, evaluated at a Romanian Outpatient Nephrology Department between October 2016 – October 2018. Bansal score was calculated for all subjects and then KFRE was used in the low mortality risk group. Outcomes were death or reaching ESRD. These outcomes were used to compare the difference between the estimated trajectory and real-life trajectory of patients. They were followed up until September 2019.ResultsFrom the total population (N=958 patients), more than half (N1=548, 57.2%) had a high mortality risk. In the remaining group with low mortality risk (N2=410, 42.8%), a significant percentage (75.4%) presented a low risk of progression to ESRD.
Real-life events consisted of 164 deaths and 31 dialysis initiations. We found similar death rates in the two groups (high versus low risk of mortality). There was no difference in the rate of dialysis initiation between subjects with a high or low risk of progression to ESRD.ConclusionsRisk prognostication for death and ESRD did not parallel the real-life trajectory of our older patients with advanced CKD.
The effect of Helicobacter pylori eradication on C-reactive protein: Results from a meta-analysis
Authors: Watanabe Jun , Kotani Kazuhiko 
Published: March 2021

IntroductionHelicobacter pylori (H. pylori) is a bacterium that causes chronic gastroduodenal infection and affects various systemic diseases. An increase in the blood level of C-reactive protein (CRP; a systemic inflammatory marker), at a low-grade chronic inflammation level, is observed in cases of infection. However, the effect of H. pylori eradication on CRP remains undetermined. Therefore, we aimed to see the circulating CRP levels in eradicated patients through a meta-analysis.Material and methodsThe PubMed database was searched from its inception to June 2020. Studies that described the CRP levels following H. pylori eradication were collected. A random-effects meta-analysis was then performed using an inverse variance with standardized mean difference.ResultsA total of 10 eligible studies (642 subjects in total) were available. The median age in the studies was 49.9 years old. The CRP level was 6.0 (median) mg/L before H. pylori eradication and 5.8 (median) mg/L after eradication. From the results of overall meta-analysis, there was found to be a significant reduction in the CRP levels with H. pylori eradication (standardized mean difference: -0.64; 95% confidence interval: -1.02 to -0.27). The result was not similarly confirmed in a subanalysis of the available randomized controlled trials.ConclusionsWeak evidence exists in terms of the effects of H. pylori eradication on the reduced CRP levels. Further research is called for.
Ubiquitin specific peptidase 49 inhibits renal fibrosis through protein phosphatase magnesium-dependent1A-mediated Smad2/3 pathway
Authors: Liu Wenrui , Guo Yue , Chen Jie , Duan Lianxiang , Zhang Chuanfu , Hu Jing , Zhou Baojuan , Lu Jianrao 
Published: March 2021

IntroductionRenal fibrosis is one of the common pathologies of chronic kidney disease. This study aimed to investigate the function of ubiquitin specific peptidase 49 (USP49) in renal fibrosis and to explore the underlying mechanismMaterial and methodsAfter analyzing the correlation between UPS49 and Smad2/3 pathways, we explored the effect of transforming growth factor-β1 (TGF-β1) on the expression of USP49. Then, the USP49 knockdown and ectopic expression human kidney-2 (HK-2) cell lines were constructed to investigate the role of USP49 in fibrosis, by determining the expression of epithelial-to-mesenchymal transition (EMT) markers (E-cadherin, α-SMA, and vimentin), phosphorylated Smad2/3 (p-Smad2/3), and protein phosphatase magnesium-dependent1A (PPMIA). Coimmunoprecipitation and ubiquitination analyses were used to determine the direct interaction between USP49 and PPM1A. The PPM1Aoverexpressed HK-2 cells were further introduced to evaluate the effects of USP49 on fibrosis. The unilateral ureteral obstruction (UUO) rats were introduced to confirm the UPS49 function in renal fibrosis in vivo.ResultsUSP49 was negatively correlated with Smad2/3 pathway, and TGF-β1 inhibited the USP49 expression. In HK-2 cells, USP49 overexpression suppressed the activity of α-SMA and p-Smad-2/3 and activated E-cadherin, vimentin, and PPMIA, whereas USP49 knockdown displayed the reverse effects. USP49 could form a complex with PPM1A. USP49 positively regulated PPM1A expression through deubiquitination. Moreover, the fibrotic effects of USP49 knockdown were significantly attenuated with ectopic expression of PPM1A. The anti-fibrotic effect was confirmed with low expressed USP49 and PPM1A in vivo.ConclusionsUSP49 might exert anti-fibrotic effects via regulating PPM1A/Smad2/3, and USP49 might be an effective target for the treatment of renal fibrosis.
Assessment of odontogenic changes in computed tomography of patients with chronic sinusitis
Authors: Czarnecka Paulina , Zatoński Tomasz , Gerber Hanna , Rutkowska Monika 
Published: March 2021

IntroductionChronic sinusitis can be caused by both laryngological and dental factors. The number of odontogenic sinusitis (OS) in last decades is increasing and seems to be underrated. A unique developmental and microbiological factors causing OS require a different therapeutic approach.Material and methodsThis study evaluated tomography examinations of 500 patients with a clinical diagnosis of chronic sinusitis. The patients were referred by laryngologists, neurologists, and maxillofacial surgeons. The scans were reanalyzed in view of the presence of odontogenic and laryngological pathologiesResultsAmong the 500 patients, 19,6% showed no inflammatory changes in the mucosa of the paranasal sinuses. All patient groups had numerous teeth missing, ranging from 27.3% to 33.2%. Most common odontogenic pathologies were periapical changes (28,8%) and the presence of teeth after improper endodontic treatment (24,2%). In the group in question dental implants (0,4%) and maxillary sinus augmentation (2,8%) were a marginal etiological factor.ConclusionsComputed tomography allows a thorough assessment of odontogenic changes. Obstruction of osteomeatal complex does not have direct influence on OS development. 43,2 % of the patients with chronic sinusitis have OS. It can be diagnosed in 50,8% of isolated right, 39,0% of isolated left and 57,8% of bilateral maxillary sinusitis patients. The results of this study can be used by dentists, maxillofacial surgeons and otolaryngologists to improve the standard of diagnosis and treatment in case of chronic odontogenic sinusitis.
Serological testing for SARS-CoV-2 in Bosnia
and Herzegovina: first report
Authors: Ašić Adna , Prguda-Mujić Jasminka , Salihefendić Lana , Bešić Larisa , Ler Daria , Čeko Ivana , Hadžović-Džuvo Almira , Jažić Sead , Konjhodžić Rijad , Marjanović Damir 
Published: March 2021

IntroductionSerological detection of SARS-CoV-2-specific immunoglobulins G
(IgG) and M (IgM) antibodies is becoming increasingly important in the man�agement of the COVID-19 pandemic.Material and methodsWe report the first results of COVID-19 serological testing in Bos�nia and Herzegovina on 2841 samples collected and analysed in 2 medical
institutions in Sarajevo. Antibody detection was performed using commer�cially available kits.ResultsIn the first cohort, 43 IgM-positive/IgG-negative and 16 IgM-posi�tive/IgG-positive individuals were detected, corresponding to 3.41% of par�ticipants having developed antibodies. In the second cohort, 4.28% partici�paConclusionsOur results suggest the need for population-wide serological
surveying in Bosnia and Herzegovina.