bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ureteroscopy‐assisted puncture for ultrasonography‐guided renal access significantly improves overall treatment outcomes in endoscopic combined intrarenal surgery
Authors: Taguchi Kazumi , Yamashita Shimpei , Hamamoto Shuzo , Deguchi Ryusuke , Kawase Kengo , Okada Tomoki , Kato Taiki , Ando Ryosuke , Okada Atsushi , Kohjimoto Yasuo , Hara Isao , Yasui Takahiro 
Published: May 2021

ObjectivesTo assess the impact and availability of ureteroscopy‐assisted puncture for percutaneous renal access during ultrasonography‐guided miniaturized (mini)‐endoscopic combined intrarenal surgery for large volume renal and/or proximal ureteral stones.MethodsWe conducted a multi‐institutional retrospective cohort study for urolithiasis treatment. Data from a total of 313 patients who underwent mini‐endoscopic combined intrarenal surgery to treat renal and/or ureteral stones between January 2016 and April 2020 were collected. We compared the outcomes between ultrasonography‐guided mini‐endoscopic combined intrarenal surgery with and without ureteroscopy‐assisted puncture (ureteroscopy‐assisted puncture(+) group [n = 126] and ureteroscopy‐assisted puncture(−) group [n = 187] group, respectively). The primary outcome was requirement for additional surgical intervention. Secondary outcomes were stone‐free rate, complications and total procedure, fluoroscopy, hospital stay, and postoperative ureteral stent placement durations.ResultsThe ureteroscopy‐assisted puncture(+) group had a lower additional surgical intervention rate and a higher stone‐free rate immediately after and 3 months after surgery than the ureteroscopy‐assisted puncture(−) group (5.6% vs 19.7%, P < 0.001; 82.5% vs 65.8%, P = 0.001; 59.5% vs 44.6%, P = 0.011). The median total procedure, fluoroscopy, and postoperative ureteral stent placement durations were 18 min, 3 min, and 5 days shorter, respectively, in the ureteroscopy‐assisted puncture(+) group. Multivariate analyses showed that ureteroscopy‐assisted puncture was associated with a decreased risk of additional surgical intervention (odds ratio 0.31, P = 0.011) and postoperative infection (odds ratio 0.34, P = 0.003) and decreased total procedure (estimate = −11 min; P = 0.011), fluoroscopy (estimate = −3 min; P = 0.034), and postoperative ureteral stent placement (estimate = −8 days; P = 0.011) durations. Female patients and those with smaller stone volumes or without hydronephrosis were identified as ideal ureteroscopy‐assisted puncture candidates.ConclusionsUreteroscopy‐assisted puncture during mini‐endoscopic combined intrarenal surgery could provide favorable surgical outcomes, especially in female patients without collecting system obstruction.
From Busan to Arusha, and beyond
Authors: Jukko Risto 
Published: May 2021

AbstractA new World Council of Churches (WCC) mission statement was presented to the member churches of the WCC at the assembly in 2013 in Busan, South Korea. The document, Together towards Life: Mission and Evangelism in Changing Landscapes (TTL), was said to be pneumatological. From God’s mission, missio Dei, there was a shift toward the mission of the Spirit, missio Spiritus. The ecumenical world was introduced to a new mission concept: “mission from the margins,” according to which the Holy Spirit was empowering those in the margins.Five years later, in 2018, in Arusha, Tanzania, the WCC Conference on World Mission and Evangelism officially adopted a short mission document entitled “The Arusha Call to Discipleship” and another document, “The Arusha Conference Report.” The conference was said to have been influenced and inspired by TTL. However, in the conference documentation, the missio Spiritus seems to have been left aside. Thus, it would seem that in recent ecumenical missiology, there has been a shift from pneumatology toward Christology as the basis of individual and communal Christian life. In light of this, this article intends to compare the WCC mission documents of 2013 and 2018 and to show that there has been a shift toward the “Christ‐connected way of life” of the disciple and how this Christ‐connected discipleship is vulnerable and wounded, as it connects with the concept of kenosis.
Moratorium and reconciliation in a post‐missionary era
Authors: Kangwa Jonathan 
Published: May 2021

AbstractThe moratorium on Western missionary labour and financial resources has been a matter of lively interest over the past five decades. Postcolonial theologians and missiologists have blamed Western missionaries for introducing Christianity without paying attention to existing cultures of local people. Despite this, the work of Western missionaries has undeniably contributed to evangelization and the advancing of Western civilization in Africa. In this context, this paper considers Colin Morris’s views on the moratorium to prevent sending missionaries and financial resources from the West. Based on an examination of his views, it analyzes two elements that shape the discourse on the moratorium in the post‐missionary era: the impact of the moratorium on Christian mission and the need for reconciliation and partnership between the churches in the global North and the global South. This paper concludes that we must promote the interdependence and mutuality of churches in the global North and the global South if the Christian imperative of making disciples of all nations is to be fulfilled.
Mission and reconciliation from a Christian‐Muslim relations perspective
Authors: Adrake Komi Dzinyefa 
Published: May 2021

AbstractThe encounter between Islam and Christianity in the mission field has created shocks that have left indelible scars across the ages. These two religions, which have never hidden their missionary intentions, have at times engaged in the struggle for supremacy on the religious chessboard, not hesitating to encroach on each other. This state of affairs has led to frustrations and conflicts between the two religious systems that the passage of time has not been able to erase. Various organizations have attempted to bring Christians and Muslims together, among these the Programme for Christian‐Muslim Relations in Africa. Reconciliation is possible. Although the path to reconciliation is still long, one who has already travelled on it gives us signs of hope. Only God can clear the path to effective reconciliation. This, however, must be combined with a new understanding of mission in both religious systems as well as a commitment on the part of both to embark on a new dynamic.
Churches in solidarity with the divided Korean Peninsula
Authors: Kim Jin Yang 
Published: May 2021

AbstractThis article explores God’s mission of reconciliation through the ecumenical efforts for peace, reconciliation, and reunification on the Korean Peninsula. It consists of three parts. The first section explores reconciliation as a means of overcoming the division system in Korea. The second section offers reconciliation as a peace process in the Korean context. The third section highlights the engagement in the reconciliation as a spiritual journey from the World Council of Churches’ global prayer campaign, which is a Christian pathway toward a peace system in the Korean Peninsula. In particular, this article demonstrates that prayer is not a strategy in our work of advocacy but a spiritual mandate and movement toward peace and justice cultivating reconciliation.
High‐entropy ferroelastic rare‐earth tantalite ceramic: (Y0.2Ce0.2Sm0.2Gd0.2Dy0.2)TaO4
Authors: Wang Jun , Wu Fushuo , Zou Ruoan , Wu Yueshu , Gan Mengdi , Feng Jing , Chong Xiaoyu 
Published: May 2021

AbstractIn this study, high‐entropy rare‐earth tantalate ceramics (Y0.2Ce0.2Sm0.2Gd0.2Dy0.2)TaO4 ((5RE0.2)TaO4) have been successfully fabricated. The possibility of formation of (5RE0.2)TaO4 was verified via first‐principles calculations. In addition, the phase structure, ferroelastic toughening mechanism, thermophysical, and mechanical properties were systematically investigated. The (5RE0.2)TaO4 ceramics have lower phonon thermal conductivity (1.2–2.6 W·m–1·K–1) in the entire temperature range than that of RETaO4 and YSZ. (5RE0.2)TaO4 has a higher fracture toughness and lower brittleness index than YSZ. The thermal expansion coefficients of (5RE0.2)TaO4 are as high as 10.3 × 10‐6 K–1 at 1200°C and Young's modulus is 66–189 GPa, and thus, (5RE0.2)TaO4 possesses great potential for application in thermal barrier coatings (TBCs).
Comparison of different sintering aids in cold sinter‐assisted densification of lead zirconate titanate
Authors: Gupta Shruti , Wang Dixiong , Randall Clive A. , Trolier‐McKinstry Susan 
Published: May 2021

AbstractCeramics such as lead zirconate titanate (PZT) tend to dissolve incongruently, and thus pose a challenge in the cold sintering process. Moist lead nitrate has previously been shown to enable a cold sinter‐assisted densification of PZT by a viscous phase sintering mechanism. In this paper, lead acetate trihydrate is demonstrated to lower the required temperature of the cold sintering step to 200°C. This densification process was described as a two‐step process: cold sintering of PZT with lead acetate trihydrate and post‐annealing the as‐cold sintered PZT ceramics. Unlike in the case of lead nitrate, PZT densification with lead acetate trihydrate occurs by a liquid phase assisted sintering mechanism, leading to an as‐cold sintered relative density of 84% at 200°C. After performing a post‐anneal step at 900°C, >97% relative densities were achieved in samples that were cold sintered with lead acetate trihydrate. This step not only densified PZT but also refined the grain boundaries. In the post‐annealed samples, the room‐temperature relative permittivity at 100 Hz was ~1600, slightly higher than that reported in samples that used lead nitrate as a sintering aid; the loss tangent was about 3.8%. For measurements at 10 Hz, the remanent polarization in both cases was ~28 µC/cm2. Both Rayleigh analysis and aging studies showed that a higher irreversible contribution to the permittivity exists in samples that used lead nitrate as a cold sintering aid.
Are cancer patients living alone more or less likely to achieve a good death? Two cross‐sectional surveys of bereaved families
Authors: Igarashi Naoko , Aoyama Maho , Masukawa Kento , Morita Tatsuya , Kizawa Yoshiyuki , Tsuneto Satoru , Shima Yasuo , Miyashita Mitsunori 
Published: May 2021

ABSTRACTThis study examined differences in sociodemographic characteristics and the achievement of a good death between cancer patients who live alone and those who do not live alone prior to death in different settings.Secondary analysis of data collected across two cross‐sectional self‐reported questionnaire surveys was undertaken.The participants were bereaved family members of cancer patients who had died in palliative care units (PCUs), acute hospitals or homes. We stratified the data by the place of death and examined the differences in sociodemographic characteristics to determine the relationship between cancer patients achieving a “good death” and whether they were living alone.The data were collected through 15,949 surveys. On the Good Death Inventory, significantly higher total scores emerged for cancer patients who were living alone than for those who not living alone in PCUs (effect size [ES] = 0.11, Student's t‐test: p < .0001), but not in acute hospitals (ES = −0.03, p = 0.74) or home care services (ES = 0.02, p = 0.86). Cancer patients who were living alone were more likely to have been female, been older and have earned a lower annual income than those who were not living alone.Thus, among those who had received specialized palliative care, there was no difference in the quality of palliative care between cancer patients who were or were not living alone.
Effectiveness of dietary diabetes insipidus bundle on the severity of postoperative fluid imbalance in pituitary region tumours: A randomized controlled trial
Authors: Koundal Hemlata , Dhandapani Manju , Thakur Pratibha , Dutta Pinaki , Walia Rama , Sahoo Sushant K. , Chhabra Rajesh , Dhandapani Sivashanmugam 
Published: May 2021

AbstractAimTo test the effectiveness of nurse‐led dietary diabetes insipidus (DI) bundle on the severity of postoperative fluid imbalance in pituitary region tumours.DesignBlinded randomized controlled trial.MethodsPatients aged 18–65 operated for sellar–suprasellar tumours in an Indian tertiary care centre were enrolled through total enumeration sampling and underwent randomization with allocation concealment during Sep 2018–Feb 2019. Pre‐operative DI, postoperative ventilation, renal failure or decompensated diabetes mellitus were excluded. Patients in the intervention group received a nurse‐led DI bundle (validated by three Delphi rounds) with four dietary components: intake of only water during thirst and avoidance of the following—added salt, high‐protein foods and caffeinated drinks. Treating clinicians and the investigator assessing outcome were blinded about enrolment. Urine output, serum sodium, vasopressin requirement and hospital stay were assessed as primary outcomes. The outcome measures were monitored daily till the 6th postoperative day. Analyses were performed on ‘intention‐to‐treat’ basis, irrespective of compliance. Independent t‐test and Chi‐square test were used.ResultsOf the initial 63 patients, 50 fulfilling criteria were randomized to two groups and assessed over six days yielding 150 patient‐days per group. There were no significant baseline differences between groups. The mean daily urine output was significantly lower in the DI bundle group than in control, both overall and among endonasal operated pituitary adenomas [3000.09(462.7) vs. 4095.71(896.4)ml & 2987.14(419.5) vs. 4064.73(1051)ml], with the greatest difference on the second postoperative day. Though hypernatraemia in controls became most prominent during days 2–3 and resolved in a week, it was significantly lower in the intervention group (12.7% vs. 30.7% overall, 11.4% vs. 29.4% endonasal adenomas). The need for vasopressin analogues and hospital stay were also significantly lower with DI bundle (p < 0.001).ConclusionThis is probably the first ever report of dietary DI bundle among operated pituitary patients, which seem to flatten the DI trend with significant benefits in polyuria, hypernatraemia, vasopressin requirement and hospital stay.Trial registrationCTRI/2018/07/015127 of ICMR.ImpactThe nurse‐led dietary DI bundle has effectively reduced the severity of DI among operated pituitary patients with significant benefits in polyuria, hypernatraemia, vasopressin requirement and hospital stay. Its implementation is simple and easy to carry out, especially in resource‐constrained institutions, where continuous monitoring and repeated serum sodium estimation are difficult.
Analyses of key mRNAs and lncRNAs for different osteo‐differentiation potentials of periodontal ligament stem cell and gingival mesenchymal stem cell
Authors: Jia Linglu , Zhang Yunpeng , Li Dongfang , Zhang Wenjing , Zhang Dongjiao , Xu Xin 
Published: May 2021

AbstractBoth human periodontal ligament stem cells (hPDLSCs) and human gingival mesenchymal stem cells (hGMSCs) are candidate seed cells for bone tissue engineering, but the osteo‐differentiation ability of the latter is weaker than the former, and the mechanisms are unknown. To explore the potential regulation of mRNAs and long non‐coding RNAs (lncRNAs), this study obtained the gene expression profiles of hPDLSCs and hGMSCs in both undifferentiated and osteo‐differentiated conditions by microarray assay and then analysed the common and specific differentially expressed mRNAs and lncRNAs in hPDLSCs and hGMSCs through bioinformatics method. The results showed that 275 mRNAs and 126 lncRNAs displayed similar changing patterns in hPDLSCs and hGMSCs after osteogenic induction, which may regulate the osteo‐differentiation in both types of cells. In addition, the expression of 223 mRNAs and 238 lncRNAs altered only in hPDLSCs after osteogenic induction, and 177 mRNAs and 170 lncRNAs changed only in hGMSCs. These cell‐specific differentially expressed mRNAs and lncRNAs could underlie the different osteo‐differentiation potentials of hPDLSCs and hGMSCs. Finally, dickkopf Wnt signalling pathway inhibitor 1 (DKK1) was proved to be one regulator for the weaker osteo‐differentiation ability of hGMSCs through validation experiments. We hope these results help to reveal new mRNAs‐lncRNAs‐based molecular mechanism for osteo‐differentiation of hPDLSCs and hGMSCs and provide clues on strategies for improving stem cell–mediated bone regeneration.
The role of SIRT2 in vascular‐related and heart‐related diseases: A review
Authors: Wu Boquan , You Shilong , Qian Hao , Wu Shaojun , Lu Saien , Zhang Ying , Sun Yingxian , Zhang Naijin 
Published: May 2021

AbstractAt present, cardiovascular disease is one of the important factors of human death, and there are many kinds of proteins involved. Sirtuins family proteins are involved in various physiological and pathological activities of the human body. Among them, there are more and more studies on the relationship between sirtuin2 (SIRT2) protein and cardiovascular diseases. SIRT2 can effectively inhibit pathological cardiac hypertrophy. The effect of SIRT2 on ischaemia‐reperfusion injury has different effects under different conditions. SIRT2 can reduce the level of reactive oxygen species (ROS), which may help to reduce the severity of diabetic cardiomyopathy. SIRT2 can affect a variety of cardiovascular diseases, energy metabolism and the ageing of cardiomyocytes, thereby affecting heart failure. SIRT2 also plays an important role in vascular disease. For endothelial cell damage used by oxidative stress, the role of SIRT2 is bidirectional, which is related to the degree of oxidative stress stimulation. When the degree of stimulation is small, SIRT2 plays a protective role, and when the degree of stimulation increases to a certain level, SIRT2 plays a negative role. In addition, SIRT2 is also involved in the remodelling of blood vessels and the repair of skin damage.
Improvements to PTSD quality metrics with natural language processing
Authors: Shiner Brian , Levis Maxwell , Dufort Vincent M. , Patterson Olga V. , Watts Bradley V. , DuVall Scott L. , Russ Carey J. , Maguen Shira 
Published: May 2021

AbstractRationale aims and objectivesAs quality measurement becomes increasingly reliant on the availability of structured electronic medical record (EMR) data, clinicians are asked to perform documentation using tools that facilitate data capture. These tools may not be available, feasible, or acceptable in all clinical scenarios. Alternative methods of assessment, including natural language processing (NLP) of clinical notes, may improve the completeness of quality measurement in real‐world practice. Our objective was to measure the quality of care for a set of evidence‐based practices using structured EMR data alone, and then supplement those measures with additional data derived from NLP.MethodAs a case example, we studied the quality of care for posttraumatic stress disorder (PTSD) in the United States Department of Veterans Affairs (VA) over a 20‐year period. We measured two aspects of PTSD care, including delivery of evidence‐based psychotherapy (EBP) and associated use of measurement‐based care (MBC), using structured EMR data. We then recalculated these measures using additional data derived from NLP of clinical note text.ResultsThere were 2 098 389 VA patients with a diagnosis of PTSD between 2000 and 2019, 72% (n = 1 515 345) of whom had not previously received EBP for PTSD and were treated after a 2015 mandate to document EBP using templates that generate structured EMR data. Using structured EMR data, we determined that 3.2% (n = 48 004) of those patients met our EBP for PTSD quality standard between 2015 and 2019, and 48.1% (n = 23 088) received associated MBC. With the addition of NLP‐derived data, estimates increased to 4.1% (n = 62 789) and 58.0% (n = 36 435), respectively.ConclusionHealthcare quality data can be significantly improved by supplementing structured EMR data with NLP‐derived data. By using NLP, health systems may be able to fill the gaps in documentation when structured tools are not yet available or there are barriers to using them in clinical practice.
The development of the tensor vastus intermedius during the human embryonic period and its clinical implications
Authors: Utsunomiya Natsuko , Kodama Ryota , Yamaguchi Yutaka , Tsuge Itaru , Yamada Shigehito 
Published: May 2021

AbstractThe tensor vastus intermedius (TVI) is a newly discovered muscle located in the anterolateral thigh area and is considered the fifth component of the quadriceps femoris muscle. There have been several papers describing its anatomical and morphological features in detail; however, many features of this muscle, such as its ontology or kinetic functions, remain unknown. The purpose of this study was to determine the initial appearance of the TVI muscle in human embryonic development and to investigate its growth and development. Histological observations were performed on 30 lower limbs of 15 human embryos from Carnegie stage (CS) 21, 22, and 23 (with crown‐rump length ranging from 18.7 to 28.7 mm). Myocyte clusters of the TVI were observed between the vastus lateralis and intermedius muscles in 7 out of 10 limbs in CS 22, indicating that the TVI arises during this stage. In CS 23, the TVI was clearly present in all specimens except one. However, neither the aponeurosis nor the tendonous structure of the TVI were observed in these embryonic stages. Formation of the conventional four components of the quadriceps muscle is completed within CS 21; therefore, our results suggest that the TVI is the last element to develop in the quadriceps femoris complex. It is posited that after the embryonic period, the TVI continues to grow, while forming the tendinous structure toward the patella and receiving vascular supply from certain vascular branches. The clinical significance of these findings is that orthopedists and plastic surgeons who perform surgical procedures within the anterolateral thigh (ALT) area should be aware of the anatomy and development of the TVI in order to reduce surgical complications. Our present research aims to contribute to a deeper understanding of the morphogenesis of the TVI and the other femoral extensor muscles.