bluuebunny/crossref_metadata_2025_split huggingface dataset:
Right ventricular free-wall longitudinal speckle tracking strain as a prognostic criterion of adverse outcomes in patients with pulmonary hypertension: a systematic review and meta-analysis
Authors: Golukhova E. Z. , Slivneva I. V. , Mamalyga M. L. , Marapov D. I. , Alekhin M. N. , Scopin I. I. , Antonova D. E. 
Published: May 2021

The absence of consensus regarding the reference values of right ventricular free wall longitudinal strain (RVFWLS) and its predictive value prompted us to conduct a systematic review and meta-analysis of publications on the predictive role of this parameter in patients with pulmonary hypertension (PH).Aim. To study the independent predictive value of RVFWLS in PH patients using 2D/3D speckle tracking echocardiography.Material and methods. Firstly, 317 publications (PubMed) and 857 Google Scholar results were selected. Of the initially identified search results, 12 articles were analyzed. The papers were cohort designed.Results. The total number of patients with PH was 1281. The mean age of patients was 54,7±6,8 years. Four studies compared the RVFWLS with a control group (n=251). The mean RVFWLS were -17,0±2,4% and -24,7±2,2% in the experimental and control groups, respectively. A meta-analysis of the difference between the mean RVFWLS values in experimental and control group patients showed its total increase in PH subjects of 8,06% (95% CI: 5,18-10,94%; p<0,00001).The total number of deaths was 268 (all-cause — 180, composite endpoint — 88). According to the meta-analysis, with an increase of 1% in RVFWLS, there is an increase in mean all-cause mortality risk by 14% (p<0,00001), as well as mean risk of adverse outcomes or PH-related events (composite endpoint) by 14% (p<0,0001).Conclusion. These results highlight the high independent predictive value of RVFWLS as a predictor of adverse outcomes or events associated with a right ventricular dysfunction progression in PH patients.
Impact of Digitalisation on Corporate Finance in the Agricultural Sector
Authors: Chernyakov Mikhail , Usacheva Olesya , Chernyakova Maria 
Published: May 2021

The purpose of our paper is to examine the interrelation between digitalisation indicators of dairy industry government regulation and economic efficiency, using large corporations of Novosibirsk Region as an example. We propose to identify an integrated system approach to evaluating the influence of state programs related to digitalisation of the dairy industry on industry performance.
A system-wide transition to digital technology in the infrastructure of dairy industry regulation is nearly totally absent from academic research. The existing literature considers the influence of state programs and policies on the industry and proposes various performance indicators. However, it is uncertain how industry digitalisation may affect these performance indicators.
To address this gap in the literature, we propose a hypothesis of dependency between digitalisation indicators and performance indicators of dairy corporations. The basis of the methodology is the calculation of a digitalisation index used to assess the efficiency of government support of the industry corporations. In order to substantiate the hypothesis, we apply a correlation and regression analysis and established interrelations between the offered criteria (digitalisation index and share) and operating performance of dairy industry economic entities.
Our results indicate general consistent patterns and interrelations between digitalisation of state regulatory programs and the performance of dairy industry corporations. Our statistical analysis reveals digital technology as a tool of government has a significant impact on business performance. The offered digitalisation criteria and patterns of performance efficiency are indicative of the possibility to manage the digitalisation process based upon preset parameters of business performance.
Our research will be of interest to specialists developing state programs and policies applying digital technology, directors of dairy companies, and scientists who conduct research in related fields, who may use our approach for evaluating and forecasting performance in the dairy industry, accounting for the impact of government regulation.
Meisoindigo inhibits cellular proliferation via down-regulation of the PI3K/Akt pathway and induces cellular apoptosis in glioblastoma U87 cells
Authors: Gu Lijuan , Zhou Yi , Ye Yingze , Zhu Xiqun , Jin Tong , Yi Wei , Xiong Xiaoxing 
Published: May 2021

Objective: The current study was to explore whether meisoindigo was effective in suppressing proliferation and inducing apoptosis of human glioblastoma multiforme U87 cells and to explore its possible mechanisms. Method: Morphological changes were observed by light microscopy. Cell counting kit-8 (CCK-8) assay was performed to detect cellular proliferation. Apoptosis was monitored by flow cytometry. Akt, phospho-Akt, PI3K, p65, phospho-p65 and apoptosis-related proteins caspase-3 and caspase-9 were examined by Western blotting assays. Immunofluorescence was used to evaluate level of P65 expression in cells. Result: Meisoindigo inhibited the proliferation of U87 cells, and the inhibitory effect increased in a dose dependent manner. Moreover, meisoindigo exposure triggered an increase in the level of caspase-3 and caspase-9, supporting its role in the activation of apoptosis. Furthermore, meisoindigo reduced the expression of PI3K, Akt, phospho-Akt, NF-κB, p65 and phospho-p65 in U87 cells, and displacement of p65 from the nucleus to the cytoplasm. Conclusion: Meisoindigo inhibits proliferation and induces apoptosis of U87 cells, probably through down-regulating the PI3K/Akt pathway and reducing nuclear translocation of NF-κB p65.
Developing a Strategy to Prevent the Effect of Unsafe Acts (Human Errors) on the Incidence of Sports Injuries
Authors: HOSSEINPOUR Eskandar , VAHDANI Mohsen , GODARZI Samad , JAVADI-NEJAD Ali 
Published: May 2021

Introduction: As with other occupations, mistakes and unsafe behaviors are among the major causes of accidents in sports. Given the harmful consequences of sport accidents, it is essential to identify ways to control and reduce these unsafe practices. Therefore, the purpose of this study was to develop a strategy to prevent the effects of unsafe practices on the occurrence of sports accidents in sports environments.
Methodology: The research was fundamental in terms of purpose and qualitative data were collected using grounded theory using a Glaser approach. The study was conducted among 20 experts in the fields of safety, occupational medicine, psychology, sports injuries, and sports management in 2020. The participants were selected to attend in-depth unstructured interviews purposefully based on the snowball method. Data were analyzed simultaneously using a set of open, selective, and theoretical coding.
Results: The results indicated that the four factors of individual, organization, job knowledge, and the relationship between individual and organization were the main causes of human error in the occurrence of sports accidents. The individual and organizational variables (as process variables) and job knowledge as well as the relationship between the individual and the organizational factors as developmental and auxiliary variables played teh major role in this field.
Conclusion: According to the causes of sport accidents, improving the personal attitude and performance, improving the organizational structure, continuous learning and training of job knowledge, as well as improving and strengthening the positive relationship between the individual and the organization can reduce the risk and promote safety. However, lack of paying attention to these factors disrupts immunity.
Assessing the Mental Workload of staff in a Bank in Hamadan by NASA-TLX Method
Authors: BAKHSHI Zohreh , MOTAMEDZADE Majid , FARHADIAN Maryam 
Published: May 2021

Introduction: Mental workload is one of the effective factors on the performance and efficiency of people working in an organization that put their health at risk. The aim of this study was to determine the mental workload of staffa working in a bank in Hamadan City of Iran by NASA-TLX method.
Methods: In this cross-sectional study, 110 bank employees were surveyed. The data were collected using demographic and NASA-TLX questionnaires. Finally, collected data were analyzed using SPSS version 21 by running descriptive statistics and statistical tests.
Results: According to the participants, the mean and standard deviation of effort and mental demand, as the most important dimensions were 81.04 ± 14.51 and 79.50 ± 18.05, respectively. The performance dimension was selected as the least important dimension with the mean and standard deviation of 64.37 ± 10.17. The results of statistical analysis showed no significant relationship between the participants' total score of mental workload and their demographic information such as age, gender, educational level, marital status, experience, and work overtime(P>0.05). The Pearson correlation coefficient showed that age (P<0.05) and work experience (P<0.01) had a significant and inverse relationship with temporal demand dimension .
Conclusion: Based on the findings, the mean of perceived mental workload of bank employees was high. Therefore, effective programs should be conducted to mitigate and reduce the mental workload and to promote mental health of bank employees.
Risk Factors of Early Periprosthetic Femoral Fracture After Total Knee Arthroplasty
Authors: Pornrattanamaneewong Chaturong , Sitthitheerarut Akraporn , Ruangsomboon Pakpoom , Chareancholvanich Keerati , Narkbunnam Rapeepat 
Published: May 2021

Abstract
BackgroundPeriprosthetic femoral fracture (PFF) is a serious complication after total knee arthroplasty (TKA). However, the risk factors of PFF in the early postoperative setting are not well documented. This study determines the risk factors of early PFF after primary TKA.MethodsThis study recruited 24 patients who had early PFF within postoperative 3 months and 96 control patients. Demographic data (age, gender, weight, height, body mass index, Deyo-Charlson comorbidity index, diagnosis, operated side, underlying diseases and history of steroid usage intraoperative outcomes), intraoperative outcomes (operative time, surgical approach, type and brand of the prosthesis), and radiographic outcomes (distal femoral width; DFW, prosthesis-distal femoral width ratio; PDFW ratio, anatomical lateral distal femoral angle; LDFA, femoral component flexion angle; FCFA and anterior femoral notching; AFN) were recorded and compared between groups. Details of PFF, including fracture pattern, preoperative deformity, and time to PFF were also documented.ResultsIn univariate analysis, the PFF group had significantly older, right side injury, rheumatoid, dyslipidemia, Parkinson patients than the control group (p < 0.05). No cruciate-retaining design was used in PFF group (p = 0.004). Differences between the prosthetic brand used were found in this study (p = 0.046). For radiographic outcomes, PFF group had significantly lower DFW but higher PDFW ratio and LDFA than the control group (p < 0.05). While FCFA and AFN were similar between groups. The fracture patterns were medial condylar (45.8%), lateral condylar (25.0%) and supracondylar fracture (29.2%). The mean overall time to PFF was 37.2 ± 20.6 days (range 8 – 87 days). Preoperative deformity was significantly different among the three patterns (p < 0.05). When analyzed using the logistic regression model, age and dyslipidemia were only two independent risk factors for early PFF. The cut-off point of age was > = 75 years, with a sensitivity of 75.0% and specificity of 78.1%. The odds ratio of dyslipidemia was 6.63 (95% confidence interval, 1.11 to 39.8).ConclusionThis study determined that age and dyslipidemia were the independent risk factors for early PFF. However, further well-controlled studies with a larger sample size were needed to address this issue.
The Treatment Efficacy of Transparasacral Approach For Presacral Tumor: A Single Center Experience
Authors: Wang Min , Yang Yongping , Zhao Linxian , He Hongyu , Li Jiannan 
Published: May 2021

Abstract
Background: Presacral tumors, also known as retrorectal tumors, locate in the presacral space and are clinically rare and the approaches for the diagnosis and treatment of presacral tumors are still deficient. The four accepted surgical approaches for presacral tumors include transabdominal approach, sacrococcygeal approach, perineal approach, and combined approach. This study aims to evaluate the treatment efficacy of transparasacral approach for presacral tumors.Methods: 23 patients (7 males and 16 females) who are diagnosed with presacral tumors and receive surgery in transsacral approach at our department were chosen. The gender, age, body mass index (BMI), and clinical symptoms were recorded. The clinical data, postoperative complications, and short and long-term rehabilitation data were recorded and analyzed. Conclusions: The surgery was performed smoothly and the patients recovered well without signs of intestinal fistula, abdominal and pelvic infection, lung infection, organ dysfunction, or organ failure. The incision edema occurred in only one patient. In terms of the histopathological types, presacral tumors can be classified into tailgut cyst (n=10), epidermoid cyst (n=5), teratoma (n=3), and lipoma (n=10). One patient diagnosed with tailgut cyst was accompanied by adenocarcinoma transition. Tumor recurrence didn’t occur in any patients. In addition, no patients complained about dysuria, sacrococcygeal sensory disturbance, or sacrococcygeal and perineal discomfort. Surgical resection with transparasacral approach is effective for the treatment of presacral tumors with the advantages of high safety, good treatment efficacy, few complications, good oncological prognosis, and fast recovery.
Metagenomic Insights Into the Microbial Communities of Inert and Oligotrophic Outdoor Pier Surfaces of a Coastal City
Authors: Tong Xinzhao , Leung Marcus H. Y. , Shen Zhiyong , Lee Justin Y. Y. , Mason Christopher E. , Lee Patrick K. H. 
Published: May 2021

Abstract
Background: Studies of the microbiomes on surfaces in built environment have largely focused on indoor spaces, while outdoor spaces have received far less attention. Piers are engineered infrastructures commonly found in coastal areas, and due to their unique locations at the interface between terrestrial and aquatic ecosystems, pier surfaces are likely to harbor interesting microbiology. In this study, the microbiomes on the metal and concrete surfaces at nine piers located along the coastline of Hong Kong were investigated by metagenomic sequencing. The roles played by different factors in shaping the taxonomic composition and functional traits of the pier surface microbiomes were determined. Metagenome-assembled genomes were reconstructed and their putative biosynthetic gene clusters were characterized in detail.Results: Surface material was found to be the strongest factor in structuring the taxonomic and functional compositions of the pier surface microbiomes. Corrosion-related bacteria were significantly enriched on metal surfaces, consistent with the pitting corrosion observed. The differential enrichment of taxa mediating biodegradation suggests differences between the metal and concrete surfaces in terms of specific xenobiotics being potentially degraded. Genome-centric analysis detected the presence of many novel species, with the majority of them belonging to the phylum Proteobacteria. Genomic characterization showed that the potential metabolic functions and secondary biosynthetic capacity were largely governed by taxonomy, rather than surface attributes and geography. Conclusions: Pier surfaces are a rich reservoir of abundant novel bacterial species. Members of the surface microbial communities use different mechanisms to counter the stresses under oligotrophic conditions. A better understanding of the outdoor surface microbiomes located in different environments should enhance the ability to maintain outdoor surfaces of infrastructures.
Estimating the Production Losses Due to Cystic Echinococcosis in Water Buffaloes (Bubalus Bubalis) in Turkey
Authors: sarıözkan savaş , Küçükoflaz Mehmet 
Published: May 2021

Abstract
Cystic echinococcosis (CE), is a neglected zoonotic parasitic disease among livestock diseases, that causes low productivity (meat, milk, fecundity), profitability and significant economic losses in water buffalo farms and serious public health problem all over the world. This study aimed at estimating the direct (condemned offal) and indirect (meat, milk, and fecundity losses) production losses due to cystic echinococcosis (CE) in water buffaloes in Turkey. A spreadsheet loss model was constructed, and the mean prevalence rate of CE was accepted as 16.4% (3.8% in males and 21.7% in females) in water buffaloes in Turkey. The annual financial losses were estimated with official and previously published data under expected (mean value), optimistic (lowered by 10%), and pessimistic (increased by 10%) scenarios with the prices current in 2020. The production losses in an infected male and female water buffalo were estimated at $54.3 and 105.3, respectively. The nation-wide losses due to CE were estimated at $1.7 million (1.4-2.1) for water buffaloes annually. In conclusion, farmers, policymakers, and the public need to be informed about the risks and financial impact of CE, and control/eradication programs should be included in policies of government at the national level after a cost/benefit analysis.
Potential of Deep Learning in drought assessment by extracting information from hydrometeorological precursors
Authors: Maity Rajib , Khan Mohd Imran , Sarkar Subharthi , Dutta Riya , Maity Subhra Sekhar , Pal Manali , Chanda Kironmala 
Published: May 2021

AbstractThis study explores the potential of the Deep Learning (DL) approach to develop a model for basin-scale drought assessment using information from a set of primary hydrometeorological precursors, namely air temperature, surface pressure, wind speed, relative humidity, evaporation, soil moisture and geopotential height. The novelty of the study lies in extracting the information from the hydrometeorological precursors through the efficacy of the DL algorithm, based on a one-dimensional convolutional neural network. Drought-prone regions, from where our study basins are selected, often suffer from the vagaries of rainfall that leads to drought-like situations. It is established that the proposed DL-based model is able to capture the underlying complex relationship between rainfall and the set of aforementioned hydrometeorological variables and, subsequently, shows its promise for the basin-scale meteorological drought assessment as revealed through different performance metrics and skill scores. The accuracy of simulating the correct drought category, among the seven categories, is also high (&gt;70%). Moreover, in general, the skill of any climate model is much higher for the primary meteorological variables as compared with other secondary or tertiary variables/phenomena, like droughts. Thus, the novelty of the proposed DL-based model also lies in the improved assessment of ensuing basin-scale meteorological droughts using the projected meteorological precursors and may lead to new research directions.
Rodzinny dialog i pojednanie jako motyw w wybranych tekstach kultury
Authors: Frąckiewicz Małgorzata Krystyna 
Published: May 2021

Dialog to przejaw właściwych relacji międzyludzkich, jakie powinny charakteryzować nie tylko społeczność, tworzoną przez rodzinę, ale także narody. Jest on drogą do pojednania i budowania więzi. Kojarzy się z małżeństwem, rodziną, stosunkami międzynarodowymi. Ich symbol to wyciągnięte do siebie dłonie lub ręce splecione, zatrzymane w uścisku, ale też zwrócone ku sobie twarze. Wskazują na to demotywatory, dzieła malarskie, eseje, fotografie, myśli, plakaty, płaskorzeźby, przysłowia, wiersze. Tak różne gatunki i formy przekazu, zróżnicowane przez tworzywo i odbiorcę, potwierdzają fakt, że nie tylko słowa uzewnętrzniają dialog i pojednanie. W ich perspektywie i recepcji dialog i pojednanie to we współczesnym świecie wartości właściwie postrzegane i kontekstowo interpretowane jako zawsze konieczne w relacjach człowiek-człowiek. Powinny one być kształcone na gruncie rodziny.
Prawa rodziców oczekujących dziecka
Authors: Sławicka Paulina , Sławicki Piotr 
Published: May 2021

Przedmiotem artykułu jest kwestia uprawnień przysługujących rodzicom oczekującym dziecka. Cel publikacji stanowi przedstawienie katalogu praw przysługujących rodzicom, jeszcze przed jego narodzeniem. Mają one zróżnicowany charakter i są uregulowane w różnych aktach prawnych, a także w przepisach o charakterze wewnętrznym. Powyższe uprawnienia dotyczą przede wszystkim kobiet w ciąży i mają charakter ochronny. Celem ich regulacji jest zapewnienie bezpieczeństwa dla ciężarnej i dziecka poczętego w trudnym okresie ciąży. Z jednej strony mają zapewnić ochronę zdrowia matki i dziecka, z drugiej zmierzają do ułatwienia funkcjonowania kobiety w ciąży. Kolejno zostaną przedstawione: definicja rodziców oczekujących dziecka, uprawnienia przysługujące kobiecie w ciąży, zarówno w prawie pracy, rodzinnym, jak i wynikające z innych gałęzi prawa, a także uprawnienie mężczyzny do uznania dziecka wynikające z Kodeksu rodzinnego i opiekuńczego.
Pracownik socjalny w sytuacji kryzysu motywacji własnej – charakterystyka zjawiska i propozycje przeciwdziałania
Authors: Łuszczyńska Maria 
Published: May 2021

Pracownik socjalny w swojej praktyce zawodowej często spotyka się z różnego rodzaju kryzysami. Są one związane z czynnikami zewnętrznymi wobec pracownika socjalnego, takimi jak sytuacja indywidualna, rodzinna jego klientów, albo też uwarunkowania społeczne czy globalne. Kryzysy mogą mieć swoje przyczyny w wewnętrznych uwarunkowaniach pracownika socjalnego jako głównego narzędzia pomagania. Ten ostatni aspekt będzie przedmiotem zainteresowania w niniejszym tekście, gdyż omawiany kryzys motywacji pracownika socjalnego jest coraz powszechniej obserwowany wśród badaczy i obserwatorów obszaru pomocy społecznej w Polsce. Ta wewnętrzna struktura, na którą składają się kompetencje, osobowość, wiedza, umiejętności, sposób przeżywania, nastawienie, postawa i wiele innych zmiennych coraz częściej ulega kryzysowi motywacji. Kryzys motywacji pracownika socjalnego nieuchronnie wpływa na obniżenie jakości jego pracy, co może negatywnie oddziaływać na klienta pomocy społecznej, ale też powodować odpływ pracowników socjalnych z zawodu. Kryzys motywacji stanowi również wyzwanie dla obszaru kształcenia, nie tylko samych pracowników socjalnych, ale też kadry kierowniczej, odpowiedzialnej za realizację usług pomocowych. W niniejszym artykule zostaną ukazane przesłanki kryzysu motywacji, skutki obniżające profesjonalną pomoc, a także sposoby przeciwdziałania temu zjawisku. Wśród nich znajdą się takie propozycje jak rekomendacje do zmian w systemie zrządzania instytucjami pomocy społecznej, wskazówki dla kierujących pracą socjalną do wykorzystania istniejących narzędzi wsparcia (np. superwizji), a także możliwe sposoby podnoszenia motywacji przez samych pracowników socjalnych w procesie samorozwoju.