bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clothes, Sensory Experiences and Autism: Is Wearing the Right Fabric Important?
Authors: Kyriacou Chrysovalanto , Forrester-Jones Rachel , Triantafyllopoulou Paraskevi 
Published: July 2021

AbstractTactile defensiveness in autistic individuals is the least investigated sensory modality. The current multi-component, explorative study aimed to understand the experiences of ten autistic adults regarding tactile defensiveness and fabrics, using semi-structured, one-to-one interviews. Participants were asked to discuss the effects of seven provided samples of fabrics and were also asked to bring their ‘favourite’ fabric (s) and express their thoughts about their choices. Using Interpretative Phenomenological Analysis and Content Analysis, the findings showed that some fabrics can impact individuals’ reported wellbeing. Participants’ experiences with several stimuli appeared to have helped them implement coping strategies. By understanding tactile defensiveness, society could move towards increasing autism-friendly approaches with appropriate fabrics. Recommendations for future research, policy and practice are also discussed.
Sensory Processing in Williams Syndrome: Individual differences and changes over time
Authors: Powell Bradley , Van Herwegen Jo 
Published: July 2021

AbstractThis study examined individual differences as well as the development of sensory processing difficulties in children with Williams syndrome (WS) using a cross-sectional (Experiment 1) and longitudinal design (Experiment 2). In Experiment 1, a clustering approach of sensory processing scores suggested two groups. Experiment 2 showed that the clusters identified in Experiment 1 were not stable across development, especially for those with high sensory impairments at either time point. Yet, most children experienced high impairments in sensory registration at both time points, suggesting impaired registration is a core phenotype of sensory processing in children with WS across development. Possible mechanisms, limitations and implications are discussed.
Effect of salinity and pH on growth, phycoerythrin, and non-volatile umami taste active compound concentration of Rhodomonas salina using a D-optimal design approach
Authors: Latsos Christos , Bakratsas Georgios , Moerdijk Tanja , van Houcke Jasper , Timmermans Klaas R. 
Published: July 2021

AbstractThe cryptophyte Rhodomonas salina is widely used in aquaculture due to its high nutritional profile. This study aims to investigate the effect of salinity and pH on the growth, phycoerythrin concentrations, and concentrations of non-volatile umami taste active compounds of R. salina, using a design of experiment approach. Rhodomonas salina was cultivated in a flat-panel photobioreactor in turbidostat mode in a range of salinity (20–40 ‰) and pH (6.5–8.5). The strain was able to grow steadily under all conditions, but the optimal productivity of 1.17 g dry weight L−1 day−1 was observed in salinity 30 ‰ and pH 7.5. The phycoerythrin concentration was inversely related to productivity, presenting higher values in conditions that were not optimal for the growth of R. salina, 7% of dry weight at salinity 40 ‰, and pH 8.5. The identification of the umami taste of R. salina was based on the synergistic effect of umami compounds 5′-nucleotides (adenosine 5′-monophosphate, guanosine 5′-monophosphate, inosine 5′-monophosphate) and free amino acids (glutamic and aspartic acids), using the equivalent umami concentration (EUC). The results indicated that an increase in pH induces the accumulation of 5′-nucleotides, resulting in an EUC of 234 mg MSG g−1 at a salinity of 40 and pH 8.5. The EUC values that were observed in R. salina were higher compared to other aquatic animals, a fact that makes R. salina promising for further research and application in the food and feed sectors.
Closed-form time derivatives of the equations of motion of rigid body systems
Authors: Müller Andreas , Kumar Shivesh 
Published: July 2021

AbstractDerivatives of equations of motion (EOM) describing the dynamics of rigid body systems are becoming increasingly relevant for the robotics community and find many applications in design and control of robotic systems. Controlling robots, and multibody systems comprising elastic components in particular, not only requires smooth trajectories but also the time derivatives of the control forces/torques, hence of the EOM. This paper presents the time derivatives of the EOM in closed form up to second-order as an alternative formulation to the existing recursive algorithms for this purpose, which provides a direct insight into the structure of the derivatives. The Lie group formulation for rigid body systems is used giving rise to very compact and easily parameterized equations.
The parallelism argument and the problem of moral luck
Authors: Nyman Anna 
Published: July 2021

AbstractRobert Hartman’s parallelism argument aims to show that resultant moral luck exists. The gist of the argument is this: because there is circumstantial moral luck in a particular circumstantial luck scenario and that scenario is analogous in important ways to a particular resultant luck scenario, the resultant luck scenario is plausibly an instance of resultant moral luck (and hence, resultant moral luck exists). I argue that there is a principled way of denying that circumstantial moral luck is present in the circumstantial luck scenario. Doing so is not enough, however, to reject Hartman’s general analogical line of reasoning since an alternative parallelism argument based on a resultant luck scenario and a circumstantial luck scenario of another kind can be made. Nevertheless, I argue that the analogy between the circumstantial luck scenario and the resultant luck scenario in both the alternative parallelism argument and its original counterpart is too weak to support the claim that resultant moral luck is present in the resultant luck scenario.
Responsible Management Education in Time of Crisis: A Conceptual Framework for Public Business Schools in Egypt and Similar Middle Eastern Context
Authors: Mousa Mohamed , Massoud Hiba , Ayoubi Rami 
Published: July 2021

AbstractRecent studies show that the adoption of RME scenarios is still a matter of concern for non-western countries ((Mousa et al., Journal of Management Development 38:681–696, 2019), 2021a, 2021b). In this paper, we theoretically propose the potential direction of RME scenarios that business schools in Egypt and other similar cultural context to implement through articulating the main antecedents of RME before and after Covid-19. we used the method of multilevel research by combining different theoretical approaches. As an outcome of our analysis, we developed five propositions which form the main antecedents of RME in Egypt and similar regional Middle East business schools before and after Covid-19.
The expanded prostate cancer index composite short form (EPIC-26) for measuring health-related quality of life: content analysis of patients’ spontaneous comments written in survey margins
Authors: Talvitie Anna-Maija , Ojala Hanna , Tammela Teuvo , Pietilä Ilkka 
Published: July 2021

Abstract
Introduction
This study investigates comments that prostate cancer patients spontaneously write in the margins of the Expanded Prostate Cancer Index Short Form (EPIC-26) questionnaire. We aim to show the possible barriers that patients face while answering the survey, and to consider how these barriers may affect the response data generated. We investigate the kind of information patients’ comments on EPIC-26 contain, and patients’ motivations to provide this information. We also study why some EPIC domains spark more comments than others.

Method
We analyzed 28 pages of transcribed comments and four pages of supplementary letters from our survey participants (n = 496). Using inductive content analysis, we generated 10 categories describing the content of participants’ comments, and four themes demonstrating their motives for commenting. The comments regarding each EPIC domain were quantified to discover any differences between domains.

Results
The sexual domain of EPIC-26 provoked over half of all comments. Patients without recent sexual activity or desire had difficulties answering sexual function questions 8–10. The lack of instructions on whether to take erectile aid use into account when answering erectile function questions led to a diversity of answering strategies. Patients with urinary catheters could not find suitable answer options for questions 1–4. All domains sparked comments containing additional information about experienced symptoms.

Conclusion
Patients are mainly willing to report their symptoms, but a lack of suitable answer options causes missing data and differing answering strategies in the sexual and urinary domains of EPIC-26, weakening the quality of the response data received.
The Myth of Equal Opportunity in Germany? Wage Inequality and the Role of (Non-)academic Family Background for Differences in Capital Endowments and Returns on the Labour Market
Authors: Consiglio Valentina S. , Sologon Denisa M. 
Published: July 2021

AbstractWhile providing equal opportunities to all members of society independent of an individual’s socio-economic background is a major objective of German policy makers, educational opportunities of children with a non-academic family background are still unequally obstructed. When analysing the labour market implications of this disadvantage, social capital as an additional source of inequality often lacks attention. Drawing on the instrumental value of rather loose contacts (i.e. weak ties) on the labour market as revealed by Granovetter (Getting a job. A study of contacts and careers, The University of Chicago Press, Cambridge, 1974), this paper goes beyond the human capital approach and includes a measure of instrumental social capital in the form of weak-tie career support in the earnings function. Applying an Oaxaca-Blinder decomposition and quantile regressions, we find a significant average wage gap between those with and without an academic family background. A large part can be explained by deficits that those from less educated families incur with respect to human and instrumental social capital: Lower educational attainment accounts for more than half of the wage gap between the two groups while fewer career support explains around five percent of the differential. Additionally, a non-academic family background is associated with a significant deficit in returns to their instrumental social capital along the wage distribution. The findings therefore suggest that inequalities of opportunity on the German labour market occur beyond the education system, as not only the quantity but also the quality of career supporting networks of those from a non-academic family are inferior.
Elicitation of solid callus cultures of Salvia miltiorrhiza Bunge with salicylic acid and a synthetic auxin (1-naphthaleneacetic acid)
Authors: Szymczyk Piotr , Szymańska Grażyna , Kochan Ewa , Szemraj Janusz , Grąbkowska Renata 
Published: July 2021

AbstractThe presented study analyses the influence of salicylic acid (SA) and the synthetic auxin 1-naphthaleneacetic acid (NAA) on total tanshinone level and on dihydrotanshinone (DHT), cryptotanshinone (CT), tanshinine I (TI) and tanshinone IIA (TIIA) level in Salvia miltiorrhiza callus cultures growing on solid Murashige and Skoog (MS) medium. The influence of SA and NAA was evaluated at 10-day intervals throughout a 80-day treatment period. SA was applied at 0.1, 0.2 and 0.4 mM, and NAA at 2.69, 13.43, 26.85 and 40.28 μM. DHT, CT, TI and TIIA concentrations were measured using HPLC. NAA did not increase the concentration of any tanshinone. SA increased content in a concentration- and time-dependent manner; however, the yields were relatively low, possibly due to the metabolic specificity of S. miltiorrhiza cultivars in Poland. Total tanshinone concentration reached 226.38 ± 37.33 μg g−1 DW after 50 days of 0.4 mM SA elicitation. After 50 days of SA elicitation, the following maximum tanshinone concentrations were observed for 0.4 mM SA: DHT (71.58 ± 12.72 μg g−1 DW), CT (108.54 ± 18.29 μg g−1 DW), TI (29.50 ± 4.13 μg g−1 DW) and TIIA (16.75 ± 2.74 μg g−1 DW). To account for these observed differences in tanshinone biosynthesis, the distribution of SA and auxin responsive cis-active motif in the proximal promoters of the mevalonic acid, methylerythritol-4-phosphate and tanshinone-precursor biosynthesis pathway genes was evaluated in A. thaliana and S. miltiorrhiza. Our findings indicate that the SA-responsive cis-active elements have a much broader distribution than those recognized by auxin-responsive transcription factors.
CO$$_{2}$$ Convection in Hydrocarbon Under Flowing Conditions
Authors: Mykkeltvedt Trine S. , Gasda Sarah E. , Sandve Tor Harald 
Published: July 2021

AbstractCarbon-neutral oil production is one way to improve the sustainability of petroleum resources. The emissions from produced hydrocarbons can be offset by injecting capture CO$$_{2}$$2from a nearby point source into a saline aquifer for storage or a producing oil reservoir. The latter is referred to as enhanced oil recovery (EOR) and would enhance the economic viability of CO$$_{2}$$2sequestration. The injected CO$$_{2}$$2will interact with the oil and cause it to flow more freely within the reservoir. Consequently, the overall recovery of oil from the reservoir will increase. This enhanced oil recovery (EOR) technique is perceived as the most cost-effective method for disposing captured CO$$_{2}$$2emissions and has been performed for many decades with the focus on oil recovery. The interaction between existing oil and injected CO$$_{2}$$2needs to be fully understood to effectively manage CO$$_{2}$$2migration and storage efficiency. When CO$$_{2}$$2and oil mix in a fully miscible setting, the density can change non-linearly and cause density instabilities. These instabilities involve complex convective-diffusive processes, which are hard to model and simulate. The interactions occur at the sub-centimeter scale, and it is important to understand its implications for the field scale migration of CO$$_{2}$$2and oil. In this work, we simulate gravity effects, namely gravity override and convective mixing, during miscible displacement of CO$$_{2}$$2and oil. The flow behavior due to the competition between viscous and gravity effects is complex, and can only be accurately simulated with a very fine grid. We demonstrate that convection occurs rapidly, and has a strong effect on breakthrough of CO$$_{2}$$2at the outlet. This work for the first time quantifies these effects for a simple system under realistic conditions.
Tumor response evaluation in patients with malignant melanoma undergoing immune checkpoint inhibitor therapy and prognosis prediction using 18F-FDG PET/CT: multicenter study for comparison of EORTC, PERCIST, and imPERCIST
Authors: Kitajima Kazuhiro , Watabe Tadashi , Nakajo Masatoyo , Ishibashi Mana , Daisaki Hiromitsu , Soeda Fumihiko , Tanemura Atsushi , Kanekura Takuro , Yamazaki Naoya , Ito Kimiteru 
Published: July 2021

Abstract
Objective
In malignant melanoma patients treated with immune checkpoint inhibitor (ICI) therapy, three different FDG-PET criteria, European Organization for Research and Treatment of Cancer (EORTC), PET Response Criteria in Solid Tumors (PERCIST), immunotherapy-modified PERCIST (imPERCIST), were compared regarding response evaluation and prognosis prediction using standardized uptake value (SUV) harmonization of results obtained with various PET/CT scanners installed at different centers.

Materials and methods
Malignant melanoma patients (n = 27) underwent FDG-PET/CT examinations before and again 3 to 9 months after therapy initiation (nivolumab, n = 21; pembrolizumab, n = 6) with different PET scanners at five hospitals. EORTC, PERCIST, and imPERCIST criteria were used to evaluate therapeutic response, then concordance of the results was assessed using Cohen’s κ coefficient. Log-rank and Cox methods were employed to determine progression-free (PFS) and overall (OS) survival.

Results
Complete metabolic response (CMR)/partial metabolic response (PMR)/stable metabolic disease (SMD)/progressive metabolic disease (PMD) with harmonized EORTC, PERCIST, and imPERCIST was seen in 3/5/4/15, 4/5/3/15, and 4/5/5/13 patients, respectively. Nearly perfect concordance between each pair of criteria was noted (κ = 0.939–0.972). Twenty patients showed progression and 14 died from malignant melanoma after a median 19.2 months. Responders (CMR/PMR) showed significantly longer PFS and OS than non-responders (SMD/PMD) (harmonized EORTC: p < 0.0001 and p = 0.011; harmonized PERCIST: p < 0.0001 and p = 0.0012; harmonized imPERCIST: p < 0.0001 and p = 0.0012, respectively).

Conclusions
All harmonized FDG-PET criteria (EORTC, PERCIST, imPERCIST) showed accuracy for response evaluation of ICI therapy and prediction of malignant melanoma patient prognosis. Additional studies to determine their value in larger study populations will be necessary.
Necessary Conditions for Boundedness of Translation Operator in de Branges Spaces
Authors: Bellavita Carlo 
Published: July 2021

AbstractThe translation operator is bounded in the Paley–Wiener spaces and, more generally, in the Bernstein spaces. The goal of this paper is to find some necessary conditions for the boundedness of the translation operator in the de Branges spaces, of which the Paley–Wiener spaces are special cases. Indeed, if the vertical translation operator $$T_\tau $$

T
τ

defined on the de Branges space $${\mathcal H}(E)$$

H
(
E
)

is bounded, then a suitably defined measure $$d\mu (z)$$

d
μ
(
z
)

is a Carleson measure for the associated model space $$K(\Theta )$$

K
(
Θ
)

. This relation allows us to state necessary conditions for the boundedness of the vertical translation $$T_\tau $$

T
τ

. Finally, similar results are also obtained for the horizontal translation $$T_\sigma $$

T
σ

.
Cutaneous body image in psoriasis: The role of attachment style and alexithymia
Authors: Troisi Alfonso , Nanni Roberta Croce , Giunta Alessandro , Manfreda Valeria , Del Duca Ester , Criscuolo Silvia , Bianchi Luca , Esposito Maria 
Published: July 2021

AbstractThe aim of this study was to estimate the contribution of adult attachment style and alexithymia to cutaneous body image in patients with psoriasis while controlling for the confounding effects of disease severity and depressive symptoms. Participants were 107 consecutive patients (60% women) with a diagnosis of plaque-type psoriasis. Cutaneous body dissatisfaction was measured with the Cutaneous Body Image Scale (CBIS) and disease severity with the Psoriasis Area and Severity Index (PASI). Depressive symptoms, attachment style and alexithymia were assessed with the Beck Depression Inventory (BDI), the Attachment Style Questionnaire (ASQ) and the Toronto Alexithymia Scale (TAS-20), respectively. Hierarchical regression analysis showed that, independently from the severity of skin disease and depressive symptoms, patients with an insecure-avoidant attachment style and higher levels of alexithymia reported greater cutaneous body dissatisfaction. Because of the cross-sectional design, the causal relationship between avoidant attachment, alexithymia and cutaneous body image cannot be determined. There was no control group. Clinical assessment of patients with psoriasis should include attachment style and alexithymia among the psychological variables related to cutaneous body dissatisfaction.
Optimization of injection dose in 18F-FDG PET/CT based on the 2020 national diagnostic reference levels for nuclear medicine in Japan
Authors: Sagara Hiroaki , Inoue Kazumasa , Yaku Hideki , Ohsawa Amon , Someya Takashi , Yanagisawa Kaori , Ohashi Shuhei , Ishigaki Rikuta , Wakabayashi Masashi , Muramatsu Yoshihisa , Fujii Hirofumi 
Published: July 2021

Abstract
Objective
Recently, the national diagnostic reference levels (DRLs) in Japan were revised as the DRLs 2020, wherein the body weight-based injection dose optimization in positron emission tomography/computed tomography using 18F-fluoro-2-deoxy-D-glucose (18F-FDG PET/CT) was first proposed. We retrospectively investigated the usefulness of this optimization method in improving image quality and reducing radiation dose.

Methods
A total of 1,231 patients were enrolled in this study. A fixed injection dose of 240 MBq was administered to 624 patients, and a dose adjusted to 3.7 MBq/kg body weight was given to 607 patients. The patients with body weight-based injection doses were further divided according to body weight: group 1 (≤ 49 kg), group 2 (50–59 kg), group 3 (60–69 kg), and group 4 (≥ 70 kg). The effective radiation dose of FDG PET was calculated using the conversion factor of 0.019 mSv/MBq, per the International Commission on Radiological Protection publication 106. Image quality was assessed using noise equivalent count density (NECdensity), which was calculated by excluding the counts of the brain and bladder. The usefulness of the injection dose optimization in terms of radiation dose and image quality was analyzed.

Results
The body weight-based injection dose optimization significantly decreased the effective dose by 11%, from 4.54 ± 0.1 mSv to 4.05 ± 0.8 mSv (p < 0.001). Image quality evaluated by NECdensity was also significantly improved by 10%, from 0.39 ± 0.1 to 0.43 ± 0.2 (p < 0.001). In no case did NECdensity deteriorate when the effective dose was decreased. In group 1, the dose decreased by 32%, while there was no significant deterioration in NECdensity (p = 0.054). In group 2, the dose decreased by 17%, and the NECdensity increased significantly (p < 0.01). In group 3, the dose decreased by 3%, and the NECdensity increased significantly (p < 0.01). In group 4, the dose increased by 14%, but there was no significant change in the NECdensity (p = 0.766).

Conclusion
Body weight-based FDG injection dose optimization contributed to not only the reduction of effective dose but also the improvement of image quality in patients weighing between 50 and 69 kg.
Familiarity and Complexity during a Takeover in Highly Automated Driving
Authors: Scharfe-Scherf Marlene Susanne Lisa , Russwinkel Nele 
Published: July 2021

AbstractThis paper shows, how objective complexity and familiarity impact the subjective complexity and the time to make an action decision during the takeover task in a highly automated driving scenario. In the next generation of highly automated driving the driver remains as fallback and has to take over the driving task whenever the system reaches a limit. It is thus highly important to develop an assistance system that supports the individual driver based on information about the drivers’ current cognitive state. The impact of familiarity and complexity (objective and subjective) on the time to make an action decision during a takeover is investigated. To produce replicable driving scenarios and manipulate the independent variables situation familiarity and objective complexity, a driving simulator is used. Results show that the familiarity with a traffic situation as well as the objective complexity of the environment significantly influence the subjective complexity and the time to make an action decision. Furthermore, it is shown that the subjective complexity is a mediator variable between objective complexity/familiarity and the time to make an action decision. Complexity and familiarity are thus important parameters that have to be considered in the development of highly automated driving systems. Based on the presented mediation effect, the opportunity of gathering the drivers’ subjective complexity and adapting cognitive assistance systems accordingly is opened up. The results of this study provide a solid basis that enables an individualization of the takeover by implementing useful cognitive modeling to individualize cognitive assistance systems for highly automated driving.