bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent Advances in Organic Photocatalyst‐Promoted Carbohydrate Synthesis and Modification under Light Irradiation
Authors: Wang Jing , Zhou Fan , Xu Yuping , Zhang Lei 
Published: January 2025

AbstractPhotoredox catalysis has been developed as a sustainable and eco‐friendly catalytic strategy, which might provide innovative solutions to solve the current synthetic challenges and barriers in carbohydrate chemistry. During the last few decades, the study of organic photocatalyst‐promoted carbohydrate synthesis and modification has received significant attention, which provides an excellent and inexpensive metal‐free alternative to photoredox catalysis as well as introduces a new fastest‐growing era to access complex carbohydrates simply. In this review, we aim to provide an overview of organic photocatalyst‐promoted carbohydrate synthesis and modification under light irradiation, which is expected to provide new directions for further investigation.
Albizia Procera‐Derived Nitrogen‐Doped Carbon: A Versatile Material for Energy Conversion, Storage, and Environmental Applications
Authors: Shah Syed Shaheen , Shaikh M. Nasiruzzaman , Rahman Tanzilur , Shams Iftekhar , Alfasane Almujaddade , Rahman Syed Masiur , Raihan Asif , Nayem S. M. Abu , Aziz Abdul 
Published: January 2025

AbstractThis review explores the diverse applications of nitrogen‐doped carbon derived from Albizia procera, known as white siris. Native to the Indian subcontinent and tropical Asia, this species thrives in varied conditions, contributing to sustainable development. The nitrogen‐rich leaves of Albizia procera are an excellent source for synthesizing nitrogen‐doped carbon, which possesses remarkable properties for advanced technologies. This material demonstrates significant potential in energy conversion and storage systems, such as supercapacitors and batteries, due to its high surface area, electrical conductivity, and chemical stability. Nitrogen doping introduces active sites that enhance charge storage, making it ideal for renewable energy applications. Additionally, this material shows promise in environmental processes like water splitting and carbon dioxide capture, where its porous structure and chemical functionality enable efficient adsorption and remediation. The review discusses synthesis methodologies, including pyrolysis and activation, to optimize its properties for energy and environmental uses. Nitrogen‐doped carbon derived from Albizia procera may expand into catalytic applications, enhancing its role in sustainable technologies. This review underscores the importance of utilizing natural resources like Albizia procera to develop materials that drive both environmental sustainability and technological innovation.
A Helically‐Twisted Stereodynamic Probe for Chiroptical Sensing of Chiral Amines through Point‐to‐Helical Chirality Transmission
Authors: Sharma Akash Kumar , Cheran Arunima , Kumar Jatish , Srivastava Aasheesh 
Published: January 2025

AbstractChiral amines and amino alcohols form an important category of molecules employed in the designing of new drugs and catalyst. Herein, we present a helically‐twisted stereodynamic dialdehyde probe 1 for the determining of absolute configuration, and enantiomeric excess of chiral amine and amino alcohols. Probe 1 is based on the pyridine‐2,6‐dicarboxamide (PDC) core and undergoes rapid interconversion between the P‐ and M‐ conformers. However, upon imine formation with chiral amines, probe 1 gets locked it in a single conformer majorly. This induces a strong CD signal in addition to changes in the UV‐vis and fluorescence signals. The CD spectral change allowed for quantitative enantiomeric excess determination of chiral amines. Circular polarized luminescence (CPL) spectra having the glum of 1×10−3 was obtained upon imine formation between probe 1 and diamine 2. Single crystal X‐ray diffraction studies (SCXRD) confirmed the twisted conformation in 1@(R)‐4 and 1@(S)‐4, stabilized by intramolecular hydrogen bonding between bound imine nitrogen and proximate amide group.
Ethylene Carbonate Free Sulfone‐Based Electrolyte for Enabling Superior Performance of High Ni‐containing Li‐Transition Metal Oxide Cathodes at High Voltage and High Temperature
Authors: Das Arpita , Riyaz Mohammed , Kobi Sushobhan , Saha Dipannita , Mukhopadhyay Amartya 
Published: January 2025

AbstractThe present study introduces an ethylene carbonate (EC) free electrolyte, composed of 1 M LiPF6 in ethyl methyl sulfone (EMS) and dimethyl carbonate (DMC) (3 : 7 by volume), for Li‐ion batteries, which is better suited for usage with higher upper cut‐off potentials, with high Ni‐containing ‘layered’ Li‐ transition metal oxide cathodes (like Li−NMC811), and at elevated temperature. The as‐designed and developed sulfone‐based electrolyte exhibits superior anodic stability and lower electrolyte resistance, while suppressing the decomposition of LiPF6 and facilitating the formation of a S‐containing, more passivating, thinner and uniform CEI layer on Li−NMC811, despite the usage of a high upper cut‐off potential of 4.5 V (vs. Li/Li+). Compared with conventional EC‐based electrolyte, the sulfone‐based electrolyte results in notably suppressed rise in impedance and improved cyclic‐stability, with capacity retentions of ~87 % (vs. ~78 % for EC‐based electrolyte) after 50 cycles @ C/10 at room temperature (going up to 4.5 V). Even at 45 °C, the sulfone‐based electrolyte results in significantly higher initial Coulombic efficiency (viz., >80 % vs. ~40 %), higher reversible capacity (~230 mAh/g vs. ~178 mAh/g) and superior cyclic stability (~74 % vs. ~46 % retention after 50 cycles @ C/10); thus, revealing its superiority for usage at elevated temperature.
Flaring of Protruding Coronary Stents Before Transcatheter Aortic Valve Replacement to Minimize Interaction—A Feasibility Study
Authors: Fang Jonathan X. , Engel Gonzalez Pedro , Villablanca Pedro A. , Frisoli Tiberio M. , Kamel‐Abusalha Louie B. , Lee James C. , Giustino Gennaro , Wang Dee Dee , O'Neill William W. , O'Neill Brian P. 
Published: January 2025

ABSTRACTBackgroundProtruding coronary artery stents can adversely affect transcatheter aortic valve replacement (TAVR) procedure. Current evidence on the topic is limited.AimsWe aim to study the clinical feasibility and safety of flaring of protruding coronary artery stents before TAVR to reduce interaction with transcatheter heart valves.MethodsTwenty consecutive patients with 22 protruding coronary stents were optimized with a dual‐diameter balloon before TAVR. Procedural success, stent and valve geometry on angiogram, periprocedural and subsequent clinical outcomes as well as valve hemodynamics on echocardiography were evaluated.ResultsProcedural success was achieved in 100% of coronary procedure and TAVR without any major complication directly related to the flaring of stents. There was no coronary artery obstruction after TAVR or visible stent or valve deformity. All valves had normal hemodynamics immediately post‐deployment with none having clinically significant aortic insufficiency. One patient had inpatient mortality unrelated to coronary stent optimization. One valve had hemodynamic valve degeneration on follow‐up which was unrelated to coronary stent flaring and the patient was asymptomatic.ConclusionFlaring of protruding coronary stents before TAVR is technically feasible and safe and can potentially minimize stent‐valve interaction for during of after TAVR.
Recent Applications of Pillararene‐Inspired Water‐Soluble Hosts
Authors: Zhu Yujie , Gao Ya , Rebek Julius , Yu Yang 
Published: January 2025

AbstractPillararenes and their derivatives have emerged in supramolecular chemistry as unique macrocycles for applications in host–guest chemistry, materials science and biomimetics. Many variations have been conceived and synthesized in recent years and in this review, we relate progress in water‐soluble versions: leaning towerarenes, extended‐pillararenes, biphenarenes, helicarenes and octopusarenes. These are applied in targeted drug delivery, selective uptake and release of aromatic guests, fabrication of gold/silver and mesoporous silica nanoparticles, cell imaging, pollutant separation, biomedicine (e. g. biofilm disruptors, taste masking containers, neuromuscular blockers, antidotes for macromolecular biotoxin) and enantioselective recognition. It is intended that this review will be helpful for research in synthetic macrocyclic chemistry and supramolecular functional systems, leading to practical applications in various research areas.
Cost‐of‐illness analysis of chronic urticaria clinical management in five countries of Latin America
Authors: Sánchez Jorge , Álvarez Leidy , Larco José Ignacio , Ensina Luis , Guidos‐Fogelbach Guillermo , Reyes‐López Cesar A. , Ramon German D. , Robles‐Velasco Karla , Cherrez‐Ojeda Ivan 
Published: January 2025

AbstractIntroductionChronic spontaneous urticaria (CSU) is a disease with a high impact on the quality of life of patients. There are some evaluations of the economic cost of the disease in developed countries, but there is little information about the economic cost of the disease in developing countries. Our aim was to assess the economic diagnostic and therapeutic expenses of CSU in five Latin American (LA) countries.MethodsA noninterventional multicenter cross‐sectional study was conducted in five LA countries: Brazil, Colombia, Ecuador, Mexico, and Peru. To determine the frequency of medical interventions as well as clinical and sociodemographic characteristics of CSU patients, questionnaires were administered to patients, primary care physicians, allergists, and dermatologists. In each country, diagnostics and therapeutic expenses were calculated by reviewing medical records, health insurance, and interviews. The main outcome was the yearly economic burden from the healthcare insurance perspective in each country.ResultsAccording to the projected costs, Brazil had the highest urticaria cost per patient/year (7009.4 USD), followed by Mexico (3695.1 USD), Ecuador (3132.8 USD), Peru (2693.9 USD), and Colombia (2392.8 USD); the cost and the frequency of use of omalizumab and antihistamines explain the total cost differences between countries. Interventions such as medical visits and exams had similar costs between countries and represented less than 10% of total urticaria cost analysis in the five countries.ConclusionThe cost of the CSU in LA varies widely based on the health insurance coverage, the cost of the therapies, and the frequency of therapies used. Strengthening national health systems, as well as following the recommendations of international guidelines, seems to reduce the cost of CSU and improve the quality of patients.
Routing in Wireless Sensor Networks Using Clustering Through Combining Whale Optimization Algorithm and Genetic Algorithm
Authors: Zhao Guoliang , Meng Xianmeng 
Published: January 2025

ABSTRACTThe development of numerous wireless sensor network (WSN) applications has sparked considerable interest in the use of these networks across various fields. These networks, which do not require infrastructure and are self‐organizing, can be rapidly deployed in most locations to collect information about environmental phenomena and transmit it to relevant hubs for appropriate action in emergency situations. Sensor nodes (SNs) in WSNs function as both sensors and relay nodes in relation to one another. As energy in these networks is limited, the nodes are supplied with only a specific amount of power. Because these networks are often located in difficult and remote areas, node batteries cannot be recharged or replaced. As a result, energy conservation is one of the most pressing concerns in these networks. Consequently, this study proposes a novel optimization technique for clustering WSNs, combining the whale optimization method and the genetic algorithm. In this work, information is transferred between cluster heads (CHs) and the sink using a combination of whale optimization and evolutionary algorithms, focusing on reducing intracluster distances and energy consumption in cluster members (CMs), while achieving near‐optimal routing. The implementation results demonstrate that the proposed technique outperforms previous methods in terms of energy consumption, efficiency, delivery rate, and packet transmission latency, considering the evolutionary capabilities of both the whale optimization algorithm and the genetic algorithm.
Effect of Cytoskeletal Linker Protein GAS2L1 on Oligodendrocyte and Myelin Development
Authors: Zou Yanping , Jin Yili , Yang Yuqian , Zhang Liuning , Feng Yuanyu , Long Yu , Xu ZhengTao , He Yuehua , Zheng Wei , Wang Shuming , He Yongxiang , Li Jiong , Li Huiliang , Luo Zhigang , Hu Chun , Xiao Lin 
Published: January 2025

ABSTRACTOligodendrocytes (OLs), the myelin‐forming cells of the central nervous system (CNS), develop from OL precursor cells (OPCs) through a complex process involving significant morphological changes that are critically dependent on the dynamic interactions between cytoskeletal networks. Growth arrest‐specific 2‐like protein 1 (GAS2L1) is a cytoskeletal linker protein that mediates the cross‐talk between actin filaments and microtubules. However, its role in OL and myelin development remains unknown. Here, we report that GAS2L1 is expressed in both OPCs and mature OLs, and that overexpression or knockdown of Gas2l1 in cultured OPCs in vitro impaired or enhanced their differentiation, respectively, while both inhibited their proliferation. We generated a Gas2l1

fl/fl
mouse line and found that mice with conditional knockout of Gas2l1 in OL lineage cells (Olig1‐Cre;Gas2l1

fl/fl
, cKO) showed an increased number of mature OLs and enhanced myelination, as well as a reduction in the branching complexity of OPCs. In addition, an alternative mouse line with postnatally induced Gas2l1 ablation specifically in OPCs (Pdfgra‐CreER

T2
;Gas2l1

fl/fl
, iKO) recapitulated the acceleration of OL and myelin development as well as the inhibition of OPC process branching. Furthermore, EdU tracking in Gas2l1 iKO mice in vivo and in their OPC cultures in vitro showed both a reduction in OPC proliferation and an increase in OL maturation. Finally, cultured OPCs from iKO mice showed an increase in filopodia extension. Taken together, our results demonstrate an effect of GAS2L1 on the regulation of OL/myelin development and may provide a novel potential therapeutic target for various diseases involving OL/myelin pathology.
Examining the Impact of Local Constraint Violations on Energy Computations in DFT
Authors: Khanna Vaibhav , Kanungo Bikash , Gavini Vikram , Tewari Ambuj , Zimmerman Paul M. 
Published: January 2025

ABSTRACTThis work examines the impact of locally imposed constraints in Density Functional Theory (DFT). Using a metric referred to as the extent of violation index (EVI), we quantify how well exchange‐correlation functionals adhere to local constraints. Applying EVIs to a diverse set of molecules for GGA functionals reveals constraint violations, particularly for semi‐empirical functionals. We leverage EVIs to explore potential connections between these violations and errors in chemical properties. While no correlation is observed for atomization energies, a significant statistical correlation emerges between EVIs and total energies. Similarly, the analysis of reaction energies suggests weak positive correlations for specific constraints. However, definitive conclusions about error cancellation mechanisms cannot be made at this time. These observations revealed by EVIs may be useful for consideration when designing future generations of semilocal functionals.
Observation of Lossless Topological Bound States from Non‐Hermitian Subspaces
Authors: Li Ze‐Zheng , Ke Shao‐Lin , Ouyang Yang , Yu Feng , Jiang Chuang , Tian Zhen‐Nan , Chen Qi‐Dai 
Published: January 2025

AbstractTopological phases of matter, with their quantized invariants, offer the potential for disorder‐resistant transport via topological bound states. Contrary to the belief that dissipation disrupts Hermiticity and Zak phase quantization, theoretical and experimental evidence of their persistence in a non‐Hermitian photonic waveguide array is presented. A three‐layer Su‐Schrieffer‐Heeger (SSH) chain is demonstrated, which can be split into a Hermitian SSH subspace and a non‐Hermitian ladder subspace through hidden symmetry. This division allows the SSH subspace to retain its topological properties, resulting in a quantized Zak phase and lossless topological bound states. Additionally, the non‐Hermitian subspace supports coherent transport dynamics, with the phase and intensity of bound states fixed at two extreme SSH layers, confirming the presence of the Hermitian subspace. These findings enhance the understanding of the interplay between non‐Hermiticity and topology and pave the way for coherent topological light transport.
Analytik neu gedacht
Authors: Letzel Thomas , Bieber Stefan 
Published: January 2025

AbstractDerzeitige Entwicklungen der analytischen Chemie spiegeln das GDCh‐Motto „Rethinking Chemistry“. So eröffnet es neue Sichtweisen, organische Proben mit ungerichteter Massenspektrometrie zu analysieren. Das erfordert aber auch, Arbeitsstrategien zu überdenken und die chemische Ausbildung anzupassen.
Green and mild approach for carbon fibers recycling from honeycomb sandwich thermoset composite wastes
Authors: Zhao Qi , Chen Junzhen , Yang Guoyu , Wang Shaozhe , Li Yujun , Jiang Jianjun 
Published: January 2025

AbstractCross‐linked bismaleimide (BMI) resin is a high‐performance thermoset resin that cannot be remelted and reshaped. Therefore, carbon‐fiber‐reinforced BMI resin (CF/BMI) composites are difficult to recycle. In this study, a green chemical method was employed to recycle aerospace honeycomb sandwich CF/BMI composite structure wastes under mild conditions. The material was first cut into a specific shape, followed by treatment in dichloromethane to separate out the CF/BMI composite laminate, and finally, the laminate was degraded in diethylenetriamine. The BMI polymer was removed from the carbon fiber surface. The degradation degree of the BMI was nearly 100 wt%, and clean carbon fibers with good mechanical properties were recovered. A possible degradation mechanism for the CF/BMI composites was proposed. Moreover, the degradation liquid products were used directly as curing agents for epoxy resin to fabricate new resin materials. Thus, the recyclability of complex structure composite wastes was maximized to achieve minimum waste generation.Highlights
A mild method was developed for recycling sandwich‐structured composites.
The composite was completely degraded (~100 wt%), recycling high‐value CF.
A degradation mechanism of the thermoset composite was proposed.
Degradation liquid was reused directly with EP to fabricate new materials.
A green recycling process for the composites was established.
Whole Exome Sequencing in a Population of Fetuses With Structural Anomalies
Authors: Burrill Natalie , Schindewolf Erica , Pilchman Lisa , Wright Renee , Crane Haley , Gebb Juliana , Khalek Nahla , Soni Shelly , Paidas Teefey Christina , Oliver Edward R. , Linn Rebecca , Moldenhauer Julie S. 
Published: January 2025

ABSTRACTObjectiveTo investigate the exome sequencing (ES) detection rate among fetuses with congenital anomalies and describe the rates in the setting of multiple versus isolated anomalies, perinatal autopsy, and family history of a previously affected child.MethodsA single‐center retrospective chart review was conducted on 397 anomalous fetuses that underwent ES from May 2012 through December 2023. Medical record review included demographics, imaging, and genetic testing.ResultsThe overall ES diagnostic rate was 34.3%. The rate of diagnosis was 31.6% in fetuses with a single anomaly and 42.6% in fetuses with 4 or more major organ systems involved. Of the fetuses with a single anomaly, lymphatic, craniofacial, skeletal, and neurological anomalies had the highest diagnostic rate on ES. 38.6% of deceased fetuses who underwent autopsy had a genetic diagnosis. Additionally, families who had a previously affected child had a 45.5% diagnostic rate.ConclusionsES is an important tool that should be offered in pregnancies affected with congenital abnormalities or at the time of fetal demise or termination. The diagnostic rate of ES in the prenatal setting is also highly dependent on comprehensive phenotyping. With diagnostic ES results, reproductive technology and testing options are available in subsequent pregnancies.
Differences in Pulmonary Artery Flow Hemodynamics Between PAH and PH‐HFpEF: Insights From 4D‐Flow CMR
Authors: Kim Bong‐Joon , Lee Jeesoo , Berhane Haben , Freed Benjamin H. , Shah Sanjiv J. , Thomas James D. 
Published: January 2025

ABSTRACTPulmonary artery (PA) flow analysis is crucial for understanding the progression of pulmonary hypertension (PH). We hypothesized that PA flow characteristics vary according to PH etiology. In this study, we used 4D flow cardiovascular magnetic resonance imaging (CMR) to compare PA flow velocity and wall shear stress (WSS) between patients with pulmonary arterial hypertension (PAH) and those with heart failure with preserved ejection fraction and pulmonary hypertension (PH‐HFpEF). We enrolled 13 PAH and 15 PH‐HFpEF patients. All participants underwent echocardiography, 4D flow CMR, and right heart catheterization. We compared right ventricular outflow tract (RVOT) flow and main pulmonary artery (MPA) hemodynamics, including peak velocity and mean and maximum WSS, between groups. PH‐HFpEF patients were older and more likely to have hypertension. PAH patients had higher mean PA pressure (47.8 ± 8.8 vs. 32.9 ± 6.9 mmHg, p < 0.001) and pulmonary vascular resistance (PVR) (8.6 ± 4.6 vs. 2.6 ± 2.2 wood unit, p < 0.001). RVOT systolic notching was more common in PAH patients (8 of 13 vs. 0 of 15), and they had shorter RVOT acceleration time (85.5 ± 20.9 vs. 135.0 ± 21.7 ms, p < 0.001). PAH patients had lower MPA Vmax (0.8 ± 0.2 vs. 1.1 ± 0.4 m/s, p = 0.032), mean WSS (0.29 ± 0.09 vs. 0.36 ± 0.06 Pa, p = 0.035), and maximal WSS (0.99 ± 0.18 vs. 1.21 ± 0.19 Pa, p = 0.011). Anterior MPA analysis confirmed lower WSS in PAH patients. PVR was negatively correlated with MPA mean WSS (r = −0.630, p = 0.002). PAH patients had lower MPA Vmax and lower mean MPA WSS in 4D flow CMR compared to PH‐HFpEF patients. These distinct PA flow characteristics suggest that the flow hemodynamics of the PA remodeling process differ depending on the underlying etiology of PH.