bluuebunny/crossref_metadata_2025_split huggingface dataset:
Üreticilerin Dip Zeytin Hasat Kararı Üzerinde Etkili Olan Faktörlerin Belirlenmesi: İzmir İli Örneği
Authors: ALTEKİN Hatip , DEMİRBAŞ Nevin 
Published: May 2021

Öz
Dip zeytin, fizyolojik olarak olgunlaşan ve yere düşen zeytinlerdir. Toplanmasının zor ve uzun bir süreç gerektirmesi nedeniyle dip zeytin hasadı genellikle üreticiler tarafından tercih edilmemektedir. Toplanmayan dip zeytinlerin hastalık ve zararlılara konukçuluk yapması ve bu nedenle bir sonraki üretim dönemini olumsuz etkilemesi teknik ve ekonomik açıdan sorun oluşturabilmektedir. Dip zeytinlerin geç toplanması ve dal zeytinlerle karıştırılması bu zeytinlerden elde edilen zeytinyağı kalitesini olumsuz etkilemektedir. Bu araştırmanın amacı, İzmir ilinin önemli zeytin üretim bölgelerinden biri olan Foça ilçesinde üreticilerin dip zeytin hasat kararı üzerinde etkili olan faktörlerin ortaya konmasıdır. Araştırmada görüşülen üretici sayısı oransal örnekleme yöntemi ile 116 olarak belirlenmiştir. Çalışmada öncelikle zeytin üreticilerinin sosyo-ekonomik özellikleri ortaya konulmuştur. Üreticilerin dip zeytin hasat kararı üzerinde etkili olan faktörlerin belirlenmesi için Binary Lojistik Regresyon Analizi’nden yararlanılmıştır. Analiz sonuçlarına göre üreticilerin eğitim düzeyi, teknik destek, örgütlenme durumu, erken ve mekanik hasat ile ek bir tarımsal faaliyetle uğraşmanın dip zeytin hasat kararı üzerinde etkili olduğu belirlenmiştir. Zeytin ve dolayısıyla zeytinyağı üretiminde kalitenin sürdürülebilirliği için dip zeytinlerin bekletilmeden hasat edilmesi ve dal zeytinlerle ayrı toplanması ve taşınması önerilmektedir.
Using Liposomes to Alleviate the Toxicity of Chelerythrine, a Natural PKC Inhibitor, in Treating Non-Small Cell Lung Cancer
Authors: Wang Jiahui , Song Yijie , Zhang Ning , Li Ning , Liu Congying , Wang Bing 
Published: May 2021

Aim of the StudyCHE can inhibit the proliferation of lung cancer cells and induce apoptosis. However, despite having in vivo toxicity, CHE has not been thoroughly investigated in term of its in vivo antitumor effect. The present study evaluated the antitumor effect of CHE on non-small cell lung cancer cell line HCC827.MethodsThe antitumor effect of CHE on HCC827 was evaluated, and its potential work mechanism was investigated. CHE long circulation liposomes (CHELPs) modified with polyethylene glycol have been optimized and characterized by in vivo pharmacokinetic studies. A HCC827 xenograft model was developed on BALB/c nude mice for the assessment of the effects of CHE and CHELP.ResultsCHE might inhibit HCC827 growth through the ROS/PKC-ϵ/caspase 3 pathway and glycolysis. The optimized CHELP remained stable after storage for 10 days at 4°C and exhibited sustained drug release, showing approximately one-fifteenth of the in vivo clearance rate and 86 times the absorption concentration of free drug. While increasing the bioavailability of CHE, CHELP showed a good therapeutic effect on HCC827 tumor-bearing nude mice and reduced the toxicity of the free drug, improving the safety of CHE.ConclusionsCHE is a candidate drug for NSCLC, and liposomes are effective in alleviating the toxicity of CHE.
CA19.9 Serum Level Predicts Lymph-Nodes Status in Resectable Pancreatic Ductal Adenocarcinoma: A Retrospective Single-Center Analysis
Authors: Coppola Alessandro , La Vaccara Vincenzo , Fiore Michele , Farolfi Tommaso , Ramella Sara , Angeletti Silvia , Coppola Roberto , Caputo Damiano 
Published: May 2021

BackgroundThe choice between upfront surgery or neoadjuvant treatments (NAT) for resectable pancreatic ductal adenocarcinoma (R-PDAC) is controversial. R-PDAC with potential nodal involvement could benefit from NT. Ca (Carbohydrate antigen) 19.9 and serum albumin levels, alone or in combination, have proven their efficacy in assessing PDAC prognosis. The objective of this study was to evaluate the role of Ca 19.9 serum levels in predicting nodal status in R-PDAC.MethodsPreoperative Ca 19.9, as well as serum albumin levels, of 165 patients selected for upfront surgery have been retrospectively collected and correlated to pathological nodal status (N), resection margins status (R) and vascular resections (VR). We further performed ROC curve analysis to identify optimal Ca 19.9 cut-off for pN+, R+ and vascular resection prediction.ResultsIncreased Ca 19.9 levels in 114 PDAC patients were significantly associated with pN+ (p &lt;0.001). This ability, confirmed in all the series by ROC curve analysis (Ca 19.9 ≥32 U/ml), was lost in the presence of hypoalbuminemia. Furthermore, Ca 19.9 at the cut off &gt;418 U/ml was significantly associated with R+ (87% specificity, 36% sensitivity, p 0.014). Ca 19.9, at the cut-off &gt;78 U/ml, indicated a significant trend to predict the need for VR (sensitivity 67%, specificity 53%; p = 0.059).ConclusionsIn R-PDAC with normal serum albumin levels, Ca 19.9 predicts pN+ and R+, thus suggesting a crucial role in deciding on NAT.
Prevalence of Malnutrition and Frailty in Elderly Cancer Patients and Resulting Impact on Primary Treatment Recommendations in Colorectal and Breast Cancer
Authors: Balzano Vittoria , Giraud Véronique Dardaine , Sauger Carine , Lefebvre Carole , Heitzmann Patrick , Lecomtef Thierry , Dorvalg Étienne 
Published: May 2021

Abstract:

Objectives
To estimate the prevalence of malnutrition in elderly cancer patients and its association with frailty and primary cancer treatment recommendations in patients with the two most prevalent cancers (colorectal cancer, CRC and breast cancer, BC) in the Centre-Val de Loire region of France.

Methods
The entire cohort of 704 patients aged 75 years or older presenting with cancer who underwent comprehensive geriatric assessment (CGA) between 2014 and 2017 was included. Nutritional status, frailty (defined by the Balducci classification system based on CGA parameters and comorbidity), and pathological criteria were analyzed in terms of the cancer treatment recommendations suggested by geriatricians both in the whole cohort and in those with CRC and BC.

Results
In the whole group of 704 patients (84.3 +/- 4.8 years), the prevalence of malnutrition was 62.9%, and was higher in CRC than in BC patients (71.1% vs 55.4%, P < 0.01). In a multivariate analysis, malnutrition and frailty (as determined by the Balducci classification system) were independently related in CRC patients (OR: 7.28, 95%CI, 1.58∼34.03; P = 0.012) and were unrelated to metastasis [odds ratio (OR): 1.34, 95%CI, 0.56∼3.18; P = 0.5]. By contrast, malnutrition in BC patients was related exclusively to the extent of metastasis (OR: 3.52, 95%CI, 1.50∼8.24; P = 0.002). It was also demonstrated that geriatricians had a greater tendency to suggest only palliative care to CRC patients presenting with malnutrition (15.4% vs 2.7%, P = 0.006) than to BC patients (9.8% vs 5.4%, NS).

Conclusion
Malnutrition in elderly cancer patients is prevalent, especially in those with colorectal cancer, where malnutrition is frailty-related and may strongly impact on cancer treatment strategies.
The Potential Clinical Significance of the Serum Iron and Ferritin Status in Lung Cancer Patients
Authors: Guo Fei Fei , Cheng Shi Jia , Liu Yi Ning , Cui Jiu Wei 
Published: May 2021

Abstract:

Background
An increasing number of studies have shown that iron, one of the indispensable trace elements in the human body, is closely related to the occurrence and development of cancer. However, few studies have clearly demonstrated the role of the iron levels in lung cancer patients, or the potential effects of inflammation on iron levels.

Methods
The clinical data for lung cancer patients and non-lung cancer participants were retrospectively analyzed. The serum iron and ferritin levels were measured and compared using a rank-sum test. The correlation between the serum iron/ferritin and C-reactive protein (CRP) was analyzed by rank correlation. The cut-off values for continuous variables were obtained by the receiver operating characteristic curve (ROC) method. An analysis of potential prognostic factors in lung cancer patients was conducted by univariate and multivariate survival analyses.

Results
The serum iron levels in patients with extensive small-cell lung cancer (SCLC) were lower than those with limited-stage SCLC, and the levels of serum ferritin and CRP in those with extensive SCLC were higher than those with limited-stage SCLC. Similarly, the serum iron levels in patients with stage IV non-small cell lung cancer (NSCLC) were lower than those of patients with stage I-III disease, and the levels of serum ferritin and CRP in those with stage IV NSCLC were higher than those in stages I-III. The serum iron level was negatively correlated with the level of CRP, while the serum ferritin level was positively correlated with CRP. The stage of lung cancer, but not the serum iron/ferritin level, was an independent prognostic factor in lung cancer patients.

Conclusions
The serum iron and ferritin levels are associated with the staging of lung cancer. The later stages of lung cancer are associated with a lower serum iron level, a higher serum ferritin level, and a higher CRP level. Inflammation may play an important role in regulating the serum iron and ferritin levels in lung cancer patients.
Peningkatan Sumber Daya Manusia Melalui Pembuatan Video Pembelajaran Bagi Guru-Guru
Authors: Kis Kiswanto , Kirana Chandra , Romadiana Parlia , Wijaya Benny , Supardi  , Raya Agustina Mardeka 
Published: May 2021

Perkembangan teknologi semakin pesat dari waktu ke waktu, ditandai dengan adanya perkembangan teknologi yang sangat pesat. Tersebarnya informasi yang semakin meluas serta informasi dalam berbagai bentuk bervariasi tersaji dalam waktu yang sangat cepat. Penyajian pesan pada era informasi saat ini senantiasa menggunakan media elektronik yaitu video pembelajaran siswa. Kendala siswa belajar dimasa pandemic covid 19 antara lain : 1). Belum meratanya akses jaringan internet, 2). Guru gagap teknologi, 3). Mahalnya biaya kuota, 4). Belum meratanya penguasaan iptek di kalangan pendidik atau guru, 5). Belum siapnya pelaksanaan proses belajar mengajar menggunakan metode pembelajaran daring, 6). Kesulitan orang tua dalam mendampingi anak-anaknya melakukan kegiatan belajar mengajar menjadi kendala yang ditemui selama proses pembelajaran jarak jauh. Untuk itulah kita perlu mengadakan kegiatan pengabdian kepada masyarakat berupa pelatihan membuat video pembelajaran untuk guru-guru SMK N 1 Pangkalpinang. Metode yang digunakan : 1). Memberikan teori tentang pengenalan dasar pembuatan video pembelajaran, 2). Metode praktek dalam membuat video pembelajaran, 3). Meberikan soal latihan. Adapun hasil yang didapatkan dari pelatihan video pembelajaran ini adalah : 1). 100 % guru senang mengikuti pelatihan video pembelajaran, 2). 100 % guru lebih suka praktek pembuatan video pembelajaran, 3). 89,3 % guru suka menggunakan aplikasi zoom, bandicam dan camtasia dalam membuat video pembelajaran, 4). 71,4 % guru bisa membuat video pembelajaran.
Формування соснового деревостану із збереженого підросту після рубки головного користування
Authors: Жуковський О. В. , Краснов В. П. 
Published: May 2021

Дослідження проведено на стаціонарному досліді, який закладено у 1988 р. у стиглому сосновому насаджені з достатньою кількістю (22000 шт.·га-1) підросту головної породи. На половині дослідної ділянки здійснено суцільну рубку головного користування з використанням валильних машин способом вузьких пасік. Другу частину ділянки розробляли традиційним методом з наступним створенням на ній культур сосни звичайної (Pinus sylvestris L.). Виявлено, що проведення суцільних рубок головного користування з використанням валильних машин способом вузько пасічної заготівлі деревини дає змогу зберегти достатню кількість підросту сосни звичайної для формування продуктивного деревостану. Застосування подібних технологій сприяє також прискорити термін відновлення лісових насаджень, ніж це відбувається способом створення лісових культур (на 5 років). Встановлено, що деревостан, що сформувався з підросту сосни звичайної, має кращі характеристики, ніж лісові культури, створені після вирубування стиглого деревостану: середній діаметр – на 14 %, середню висоту – на 18 %. Водночас, враховуючи різницю між віком штучних і відновлених з підросту деревостанів – 5 років, можна стверджувати, що відзначені відмінності значно менші. Відмінності у рості насаджень виявлено і під час аналізу розподілу дерев за категоріями санітарного стану, якістю та класами Крафта. Так, основна частка дерев належить до ІІІ-ІV категорій санітарного стану: 65 % – у варіанті із збереженням підросту та 49 % – у варіанті зі створенням соснових культур.
Sandsack Physical Activity Increasing Balance Score in Children with Down Syndrome
Authors: Puspitosari Aniek 
Published: May 2021

Background: Down syndrome children have motoric and balance problems. Balance problems cause the child to be unable to maintain posture. Physical activity effective to stimulate development motor skills and balance in children. Sandsack physical activity can be applied to optimizing balance in children with down syndrome. The aim of the study was to investigate the effect of sandsack physical activity on balance in children with Down Syndrome.
Methods: Quantitative research with pre-experimental research design one group pretest-posttest with a sample size of 13 children with Down syndrome in SLBN Surakarta. Eight sandsack physical activity models are provided in each session. Four sandsack physical activity models per sessions. Balance is measured by sixteen balance test before and after 12 section. The data analysis method uses a paired sample t-test of SPSS.
Results: Paired sample t-test results showed that sig. (2-tailed) < 0.05. The increase in the balance score occurred after being given the sandsack physical activity intervention (mean difference of 6.39). Sandsack physical activity intervention have a possitive and significant effect on balance in Down Syndrome children (ρ = 0.001). Most of Down Syndrome children in SLBN Surakarta were male (53.8%). Down Syndrome children in SLBN Surakarta is dominated at the age of 8 and 14 years old (23.1%). BMI score of Down syndrome children in SLBN Surakarta was 15.50 (15.4%).
Conclusion: Sandsack physical activity intervention affects the balance in Down Syndrome children. Sandsack physical activity improved balance in children with Down Syndrome and should be applied in conjunction with physical and occupational therapy programs.
Diadochokinetic Rate Quantification in 5 to 14 Year Old Children
Authors: Pratomo Hafidz Triantoro Aji 
Published: May 2021

ABSTRACT
Background: Diadochokinetic Rate (DDK) is an ability of repeating a series of sounds quickly and repeatedly. This ability is one of variables to measure speaking ability. The need for normative data is important to provide prediction appropriately in order to establish speaking disorder diagnosis. This research aims to find quantitative data (DDK) in 5 to 14 year old children.
Methods: The research employed observational approach. Data was collection was conducted through face-to-face examination with students as enumerator. Each of enumerators has been trained on how to examine and to document data, as indicated with audiovisual recording. Data was collected on January 2020. A total of 100 respondents were included into analysis criteria. Respondents were 5-14 year old normal children. Data analysis was conducted using descriptive analysis.
Results: The research found data of Diadochokinetic Rate quantification at syllable and word levels. Quantification data shows the difference between nonsense syllable words and words. There was a difference of quantitative data in each of age groups. Analysis on examination result was carried out using mean and standard deviation scores.
Conclusion: The finding of research showed recent data of DDK in 5 to 14 year old year children. Data can be used as the material of speech therapy examination analysis. Further researchers are required to see DDK ability broadly in each of age groups.
The Effect of the Morphological Quenching Mechanism on Star Formation Activity at 0.5 < z < 1.5 in 3D-HST/CANDELS
Authors: Lu Shiying , Fang Guanwen , Gu Yizhou , Yuan Qirong , Cai Zhen-Yi , Kong Xu 
Published: May 2021

Abstract
Several mechanisms for the transformation of blue star-forming to red quiescent galaxies have been proposed, and the green valley (GV) galaxies amid them are widely accepted in a transitional phase. Thus, comparing the morphological and environmental differences of the GV galaxies with early-type disks (ETDs; bulge dominated and having a disk) and late-type disks (LTDs; disk dominated) is suitable for distinguishing the corresponding quenching mechanisms. A large population of massive (M
* ≥ 1010
M
⊙) GV galaxies at 0.5 ≤ z ≤ 1.5 in 3D-HST/CANDELS is selected using extinction-corrected (U–V)rest color. After eliminating any possible active galactic nucleus candidates and considering the “mass-matching,” we finally construct two comparable samples of GV galaxies with either 319 ETD or 319 LTD galaxies. Compared to the LTD galaxies, it is found that the ETD galaxies possess higher concentration index and lower specific star formation rate, whereas the environments surrounding them are not different. This may suggest that the morphological quenching may dominate the star formation activity of massive GV galaxies rather than the environmental quenching. To quantify the correlation between the galaxy morphology and the star formation activity, we define a dimensionless morphology quenching efficiency Q
mor and find that Q
mor is not sensitive to the stellar mass and redshift. When the difference between the average star formation rate of ETD and LTD galaxies is about 0.7 M
⊙ yr−1, the probability of Q
mor ≳ 0.2 is higher than 90%, which implies that the degree of morphological quenching in GV galaxies might be described by Q
mor ≳ 0.2.
Testing General Relativity with NuSTAR Data of Galactic Black Holes
Authors: Tripathi Ashutosh , Zhang Yuexin , Abdikamalov Askar B. , Ayzenberg Dimitry , Bambi Cosimo , Jiang Jiachen , Liu Honghui , Zhou Menglei 
Published: May 2021

Abstract
Einstein’s theory of General Relativity predicts that the spacetime metric around astrophysical black holes is described by the Kerr solution. In this work, we employ state-of-the-art relativistic reflection modeling to analyze a selected set of NuSTAR spectra of Galactic black holes to obtain the most robust and precise constraints on the Kerr black hole hypothesis possible today. Our constraints are much more stringent than those from other electromagnetic techniques and, with some sources, we find stronger constraints than those currently available from gravitational waves.
Comparison of different methods to assess the distribution of alien plants along the road network and use of Google Street View panoramas interpretation in Sicily (Italy) as a case study
Authors: Barone Giulio , Domina Gianniantonio , Di Gristina Emilio 
Published: May 2021

The survey by foot in the field is compared to the survey from a car, the photo-interpretation of Google Street View (GSV) panoramas continuously and at intervals of 1.5 km and the photo-interpretation of Google Earth aerial images on a 10 km stretch of road in Sicily. The survey by foot was used as reference for the other methods. The interpretation of continuous GSV panoramas gave similar results as the assessment by car in terms of the number of species identified and their location, but with lower cost. The interpretation online of aerial photos allowed the identification of a limited number of taxa, but gave a good localisation for them. Interpretation of GSV panoramas, each of 1.5 km, allowed the recognition of twice as many taxa as the interpretation of aerial photos and taking half the time, but did not allow a complete localisation.
None of these methods alone seems sufficient to carry out a complete survey. A mixture of different techniques, which may vary according to the available resources and the goal to be achieved, seems to be the best compromise.
To further test the capabilities of the survey using the interpretation of GSV panoramas every 1.5 km along the roads, we proceeded to study the alien plants along 3500 km of the road network on the island of Sicily. This survey identified only 10% of the known species for the region, but allowed us to trace the distribution of invasive species whose distribution is currently poorly recorded.
Au fil de l’Orne. Caen et son cabotage au temps de Mazarin et de Louis XIV
Authors: Delobette Édouard 
Published: May 2021

Découvert dans le fonds de la Table de marbre de l’amirauté de Rouen, le carnet de Jacques Toustain, marchand de Caen et commis à la ferme des droits de l’amiral de France, a permis de connaître le trafic à la sortie du port de Caen de 1654 à 1658. La base de données construite à partir des congés de l’amirauté fournit les informations générales sur le trafic au cabotage de Caen, et, de manière moins complète, les tonnages et destinations empruntées par les caboteurs. Il a été aussi possible de mieux connaître les acteurs et leurs stratégies par une mise en perspective chronologique à la fin du règne de Louis xiv afin d’apprécier l’évolution du cabotage à Caen et en faisant appel à la documentation d’archives étrangères.
John Ware (1807-1841) : traces et mémoire d’une trajectoire goréenne
Authors: Gachon Nicolas 
Published: May 2021

Il existe peu de travaux sur les occupations britanniques de Gorée de 1663 à 1664, de 1758 à 1763, de 1779 à 1784, de 1800 à 1804 et, les Français ayant repris Gorée en 1804 mais l’ayant reperdue la même année, de 1804 à 1816. Ces périodes sont riches d’enseignements sur les relations entre les populations locales et les sujets de la puissance occupante. Elles sont en cela complémentaires aux cas mieux documentés des occupations françaises. Des unions interraciales impliquant des sujets britanniques se sont nouées à Gorée au xix e siècle, métissages dont la mémoire parfois douloureuse, souvent parcellaire et toujours en quête de sens s’est construite pour partie autour de la conscience diffuse d’une ascendance britannique. La trajectoire du dénommé John Ware né à Gorée en 1807 sous occupation britannique et décédé en 1841 sous occupation française, la mémoire contemporaine de cette trajectoire et l’analyse de ses mécanismes forment l’objet de la présente étude de cas.
« Quand je serai grande… »
Authors: Mikanga Emmanuelle , Martin Amélie 
Published: May 2021

Cet article prend appui sur l’accompagnement éducatif d’une monitrice éducatrice réalisé auprès d’un garçon de 8 ans accueilli en mecs . À partir de la situation de Nino, nous proposons une première réflexion sur l’impact des normes de genre dans les pratiques professionnelles et les actions éducatives des travailleur·euse·s sociaux·les. Comment accompagner Nino dans la construction de son identité sexuée ? Comment ne pas influencer ses choix et être dans le respect de ses propres questionnements ?