bluuebunny/crossref_metadata_2025_split huggingface dataset:
Language Recovery after Brain Injury: A Structural Network Control Theory Study
Authors: Wilmskoetter Janina , He Xiaosong , Caciagli Lorenzo , Jensen Jens H. , Marebwa Barbara , Davis Kathryn A. , Fridriksson Julius , Basilakos Alexandra , Johnson Lorelei P. , Rorden Chris , Bassett Danielle , Bonilha Leonardo 
Published: December 2021

Aphasia recovery after stroke depends on the condition of the remaining, extralesional brain network. Network control theory (NCT) provides a unique, quantitative approach to assess the interaction between brain networks. In this longitudinal, large-scale, whole-brain connectome study, we evaluated whether controllability measures of language-related regions are associated with treated aphasia recovery. Using probabilistic tractography and controlling for the effects of structural lesions, we reconstructed whole-brain diffusion tensor imaging (DTI) connectomes from 68 individuals (20 female, 48 male) with chronic poststroke aphasia who completed a three-week language therapy. Applying principles of NCT, we computed regional (1) average and (2) modal controllability, which decode the ability of a region to (1) spread control input through the brain network and (2) to facilitate brain state transitions. We tested the relationship between pretreatment controllability measures of 20 language-related left hemisphere regions and improvements in naming six months after language therapy using multiple linear regressions and a parsimonious elastic net regression model with cross-validation. Regional controllability of the inferior frontal gyrus (IFG) pars opercularis, pars orbitalis, and the anterior insula were associated with treatment outcomes independently of baseline aphasia severity, lesion volume, age, education, and network size. Modal controllability of the IFG pars opercularis was the strongest predictor of treated aphasia recovery with cross-validation and outperformed traditional graph theory, lesion load, and demographic measures. Regional NCT measures can reflect the status of the residual language network and its interaction with the remaining brain network, being able to predict language recovery after aphasia treatment.SIGNIFICANCE STATEMENTPredicting and understanding language recovery after brain injury remains a challenging, albeit a fundamental aspect of human neurology and neuroscience. In this study, we applied network control theory (NCT) to fully harness the concept of brain networks as dynamic systems and to evaluate their interaction. We studied 68 stroke survivors with aphasia who underwent imaging and longitudinal behavioral assessments coupled with language therapy. We found that the controllability of the inferior frontal regional network significantly predicted recovery in language production six months after treatment. Importantly, controllability outperformed traditional demographic, lesion, and graph-theoretical measures. Our findings shed light on the neurobiological basis of human language and can be translated into personalized rehabilitation approaches.
Perioperative changes of FGF23 in patients undergoing surgery for primary hyperparathyroidism
Authors: Fořtová Magdaléna , Hanousková Lenka , Valkus Martin , Čepová Jana , Průša Richard , Kotaška Karel 
Published: December 2021

Background
Fibroblast growth factor 23 (FGF23) is a key regulator of urine phosphate excretion. The aim of the study was to investigate the perioperative (intraoperative and postoperative) changes of plasma intact and C-terminal FGF23 (iFGF23, cFGF23) concentrations in patients with primary hyperparathyroidism (pHPT) submitted to surgery.

Materials and methods
The study involved 38 adult patients with pHPT caused by adenoma. Parathyroid hormone (PTH) levels were investigated intraoperatively (just before the incision and 10 min after adenoma excision). cFGF23, iFGF23, phosphate, estimated glomerular filtration rate (eGFR), and procollagen type 1 N-terminal propetide (P1NP) were measured intraoperatively and postoperatively (next day after the surgery).

Results
PTH levels decreased intraoperatively (13.10 pmol/L vs 4.17 pmol/L, P< 0.0001). FGF23 levels measured intraoperatively were at the upper level of reference interval. cFGF23 decreased postoperatively compared with the values measured just before the incision (cFGF23: 89.17 RU/mL vs 22.23 RU/mL, P< 0.0001). iFGF23 decreased as well, but the postoperative values were low. Postoperative inorganic phosphate values increased (1.03 mmol/L vs 0.8 mmol/L, P= 0.0025). We proved significant negative correlation of perioperative FGF23 with inorganic phosphate (cFGF23: Spearman’s r = −0.253, P= 0.0065; iFGF23: Spearman’s r = −0.245, P= 0.0085). We also found that FGF23 values just before incision correlated with eGFR (cystatin C) (cFGF23: Spearman’s r = −0.499, P= 0.0014; iFGF23: Spearman’s r = −0.413, P= 0.01).

Conclusion
Intraoperative iFGF23 and cFGF23 did not change despite PTH decreased significantly. cFGF23 and iFGF23 significantly decreased 1 day after parathyroidectomy and are associated with increase of inorganic phosphate in pHPT patients. cFGF23 and iFGF23 just before incision correlated with eGFR (cystatin C). Similar results found in both iFGF23 and cFGF23 suggest that each could substitute the other.
Altas capacidades: xestión de aulas avanzadas
Authors: Ferro Fontenla José Eladio 
Published: December 2021

O alumnado con Altas Capacidades forma parte da diversidade que debe atender a escola.
Tal como establece a lexislación educativa actual (LOE, LOMCE, LEI 3/2020), a resposta ás súas necesidades específicas de apoio educativo ha de darse nun contexto inclusivo, afastada de propostas segregacionistas que pretendan educar a estes estudantes illados do resto da poboación escolar.
A escola é capaz de tomar decisións e poñer en práctica medidas de resposta inclusivas para atender as diferenzas. Estas medidas han de partir de propostas colectivas, preventivas, que favorezan a todo o alumnado, establecendo plans e programas de actuación que abranguerán dende o centro como sistema ata o plano individual, superando a causalidade lineal e individualista da práctica docente, onde o éxito ou o fracaso débense a un único elemento, cara a unha causalidade circular que busca corresponsables e implica a un equipo de persoas: profesorado, alumnado e familias, que analizan, planifican, interveñen e avalían, poñendo en práctica medidas innovadoras de atención á diversidade. As aulas avanzadas recollen estas e outras premisas e pretenden proporcionar, dende a escola ordinaria, unha resposta inclusiva de calidade a todo o alumnado, tamén ao alumnado de Altas Capacidades.
APPLICATION OF EDIBLE FILM AND COATING BASED ON ALOE VERA GEL FOR PRESERVATION OF PHYSICOCHEMICAL PROPERTIES OF PHYSALIS PERUVIANA L. FRUITS
Authors: Ali Marwa Rashad , Abdel - Aziz Mohamed Emad- El deen 
Published: December 2021

The calyx removing of Physalis peruviana fruits for production of fresh cut fruit makes its shelf life shorter. So, Aloe vera gel (AV) used as edible film and coating for increasing the fruit shelf life of fresh cut Physalis fruit. The physical parameter of prepared AV films was investigated such as: Thickness, water vapor permeability (WVP) and water solubility. The current study evaluates the effect of AV film and coating for maintain the Physalis peruviana fruits without calyx at 5±1°C and 95 % RH for 30 days. AV gel film was effective in controlling the fungal decay. which recorded the lowest value (4%) and reduced deterioration in all other physicochemical properties of Physalis fruit comparing with control. This study showed that the AV gel could be suitable for producing an edible film and coating with good physical characteristics such as low WVP (0.0037g/m2.h.mmHg). AV's low WVP appeared to have a great impact on maintaining post-harvest quality especially reducing the percentage of weight loss of coated fruit during storage.
Our Comeback Story: Impostor Syndrome in the Archival Profession
Authors: Anderson-Zorn April K. , Davis Michael Andrew , Nowak Danielle , Stankrauff Alison 
Published: December 2021

ABSTRACT
In 2019, a group of archivists participated in two conference sessions focused on impostor syndrome in the archives field. Though no comprehensive study on impostor syndrome has been undertaken in the archives profession, the authors listened to numerous stories of the phenomenon among audience members. This perspectives article considers the presence and impact of impostor syndrome in the archives field. The authors define the phenomenon, review literature on its influences in the information science profession, include stories of archives professionals working with impostor syndrome, and offer suggestions for working through impostor syndrome.
Conditions for Granting Compulsory License for Dependent Invention Use
Authors: Puchinina M. M. 
Published: December 2021

The paper deals with the institution of compulsory licensing for dependent inventions. Currently, its most important application is in the pharmaceutical industry. In order to launch generic drugs that are dependent inventions pharmaceutical companies have to enter into licensing agreements with the developers of original drugs. The law enforcement practice that began in 2018 in the Russian Federation showed that paragraph 2 of Art. 1362 of the Civil Code of the Russian Federation, which establishes the conditions for granting a compulsory license for the use of a dependent invention, needs to be harmonized and supplemented in order to protect and regulate the balance of private and public interests. To solve this problem, the author analyses the wording of the corresponding legal norm found in international agreements, in particular in the TRIPS Agreement, and in the national legislation of different countries as well as the effectiveness of its application. Based on the results of the study, possible clarifications are given to the conditions for granting a compulsory license for the use of a dependent invention under paragraph 2 of Art. 1362 of the Civil Code of the Russian Federation.
Appealing against Decisions on Reimbursement of Procedural Costs Made in accordance with Part 3 of Art. 131 of the Criminal Procedure Code of the Russian Federation
Authors: Zelenin S. R. 
Published: December 2021

The legality and validity of the decisions of the investigator, inquirer and the prosecutor on the payment of the amounts related to procedural costs remain problematic due to the absence in the law of a mechanism ensuring the judicial procedure for their appeal. In order to fill this gap, the author studies the possibilities of introducing a procedure similar to the one enshrined in Art. 125 of the Code of Criminal Procedure of the Russian Federation. The paper analyzes the positions of the Resolution of the Constitutional Court of the Russian Federation No. 18-P dated May 13, 2021. It concerns the victims’ appeal against the decisions of the investigator and the head of the investigative body regarding the reimbursement of expenses for a representative. Some examples of judicial practice for resolving other disputes related to the reimbursement of procedural costs are also analyzed. It is concluded that the right of a person claiming to receive the amounts provided for in Part 2 of Art. 131 of the Code of Criminal Procedure of the Russian Federation against a judicial appeal made at his request is universal and does not depend either on his status in a criminal case, or on the type of the indicated amounts, or on the body or official that made the contested decision. Taking into account the practice of applying other norms on appealing against decisions of the investigating bodies, it was proposed to introduce Art. 125.2. The author formulate its content given the characteristics of the participants in the proceedings and the powers of the court to resolve the complaint.
Calculating Fuzzy Inverse Matrix Using Linear Programming Problem: An Improved Approach
Authors: Babakordi Fatemeh , Taghi-Nezhad Nemat Allah 
Published: December 2021

Calculating the matrix inverse is a key point in solving linear equation system, which involves complex calculations, particularly when the matrix elements are (Left and Right) fuzzy numbers. In this paper, first, the method of Kaur and Kumar for calculating the matrix inverse is reviewed, and its disadvantages are discussed. Then, a new method is proposed to determine the inverse of fuzzy matrix based on linear programming problem. It is demonstrated that the proposed method is capable of overcoming the shortcomings of the previous matrix inverse. Numerical examples are utilized to verify the performance and applicability of the proposed method.
A Novel Generator of Continuous Probability Distributions for the Asymmetric Left-skewed Bimodal Real-life Data with Properties and Copulas
Authors: Shehata Wahid A. M. , Yousof Haitham , Aboraya Mohamed 
Published: December 2021

This paper presents a novel two-parameter G family of distributions. Relevant statistical properties such as the ordinary moments, incomplete moments and moment generating function are derived. Using common copulas, some new bivariate type G families are derived. Special attention is devoted to the standard exponential base line model. The density of the new exponential extension can be “asymmetric and right skewed shape” with no peak, “asymmetric right skewed shape” with one peak, “symmetric shape” and “asymmetric left skewed shape” with one peak. The hazard rate of the new exponential distribution can be “increasing”, “U-shape”, “decreasing” and “J-shape”. The usefulness and flexibility of the new family is illustrated by means of two applications to real data sets. The new family is compared with many common G families in modeling relief times and survival times data sets.
The Health Determinants of Accessibility to Clubfoot Treatment in LMICs: A Global Exploration of Barriers and Solutions
Authors: Sheik-Ali Sharaf , Navarro Sergio M , Keil Evan J , Keil Evan , Johnson Walter , Lavy Chris 
Published: December 2021

Background: Clubfoot or Congenital Talipes Equinovarus (CTEV) treatment in newborn infants involves simple, non-invasive manipulation and is primarily managed non-surgically if identified early. In low- and middle-income countries (LMICs), less than 15% of patients with CTEV access treatment. This cross-sectional questionnaire study conducted descriptive and regression analysis of institutional reasons for CTEV management in LMICs.
Methods: A cross-sectional study was undertaken of 1,489 medical institutions in 62 LMICs. Data were evaluated from the “World Health Organization Situation Analysis tool” database. We analyzed characteristics of institutions that manage and did not manage CTEV. With the use of a multivariate linear regression model, we identified a set of factors linked to referral for non-management of CTEV.
Results: A total of 72.7% (1,083/1,395) of institutions surveyed did not manage CTEV. The most common reason cited for not managing CTEV was a lack of sufficient skills, 92.1% (668/725, P<0.001). A total of 39.4% (286/725) of institutions also cited a lack of functioning equipment as a reason. Multivariate linear regression analysis showed lack of training, lack of supplies, and lack of functioning equipment were most closely related to non-management of CTEV.
Conclusion and Global Health Implications: We identified that failure to manage CTEV may result from a lack of skills and medical equipment. Increasing the capacity of sustainable training programs may reduce the presently available skill deficit in treating CTEV in LMICs and provide improved health outcomes for those with CTEV. While considerable progress has been made in building capacity for the treatment and management of CTEV in LMICs, structured training programs that support conservative manipulative methods to manage CTEV should be initiated globally.

Copyright © 2021 Sheik-Ali et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.
Determinants of HIV Testing Uptake among Women (aged 15-49 years) in the Philippines, Myanmar, and Cambodia
Authors: Myint Wah , Washburn David , Colwell Brian , Maddock Jay 
Published: December 2021

Background: Many countries have been trying to eliminate Mother-to-Child transmission of the Human Immunodeficiency Virus (HIV) and achieve the 90-90-90 target goals. The targets mean that 90% of People Living with HIV (PLWHIV) know their HIV status, 90% of those who are infected receive Antiretroviral treatment (ART), and 90% of those achieve viral suppression. Despite some progress, the goals have not been met in the Philippines, Myanmar, and Cambodia, countries with relatively high or growing HIV prevalence. This study identifies the sociodemographic determinants of testing among women in these countries so that better health education and stigma reduction strategies can be developed.
Methods: Descriptive and multivariable analyses were conducted using Demographic and Health Survey data conducted in the Philippines (2017), Myanmar (2015/2016), and Cambodia (2014). The outcome variable was having ever been tested for HIV. Independent variables included knowledge and attitudes about HIV and social determinants of health.
Results: A significant difference in testing rates among women was observed (the Philippines: 5%, Myanmar: 19%, Cambodia: 42%). In Myanmar and Cambodia, women who had more HIV knowledge and less stigma towards PLWHIV were more likely to get tested for HIV than those who did not. Marital status, education, wealth were strong predictors for HIV testing among women. Younger women aged 15-19 and those who live in the rural areas were less likely to get HIV tested than older and those living in urban areas. Employed women were less likely to seek an HIV test than the unemployed in Myanmar and Cambodia, whereas, in the Philippines, the opposite relationship was found.
Conclusion and Global Health Implications: Women with less education and those less familiar with HIV should be targeted for HIV testing interventions. Stigma reduction and different testing strategies could facilitate early screening leading to improved HIV testing among women.

Copyright © 2021 Myint et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.
Alpha-1 Antitrypsin Deficiency and Risk of Lung Cancer in Never-Smokers: A Multicentre Case-Control Study
Authors: Tubío-Pérez Ramón Antonio , Torres-Durán María , García-Rodríguez María Esmeralda , Candal-Pereira Cristina , Rey-Brandariz Julia , Pérez-Ríos Mónica , Barros-Dios Juan , Fernández-Villar Alberto , Ruano-Raviña Alberto 
Published: December 2021

Abstract
Background
Lung cancer (LC) is the most commonly diagnosed cancer and the leading cause of cancer-related death in both sexes worldwide. Although its principal risk factor is smoking habit, there are genetic mutations, such as alpha-1 antitrypsin deficiency (AATD), that have been related with increased risk This study is the continuation of an earlier one published by the same group in 2015, aimed at analysing risk of LC in never-smokers, associated with carriers of the AATD genotype.
Methods
A multicentre case-control study was conducted in Spain across the period January 2011 to August 2019. Cases were patients with LC, and controls were patients, all never-smokers, undergoing major non-cancer-related surgery. Data were collected on epidemiological characteristics, exposure to environmental tobacco smoke (ETS), residential radon levels, and alpha-1 antitrypsin (AAT) genotype.
Results
The study included 457 cases (42%) and 631 controls (58%), with a predominance of women. The most frequent histological type was adenocarcinoma (77.5%), followed by squamous cell carcinoma (7.7%). No association of risk of LC was found with the status of AATD genotype carrier, both overall and broken down by age, sex, or exposure to ETS.
Conclusions
No risk association was found between being a carrier of an AAT deficiency genotype and LC among never-smokers. Even so, new studies are required to provide fuller information in this regard with respect to never-smokers, and possibly even include previous respiratory diseases.
Investigating The Environmental Kuznets Curve (Ekc) Hypothesis For India: Does India Have Enough Capital To Supplement Renewable Energy Usage In The Correction of Carbon Emissions?
Authors: Rej Soumen , Nag Barnali 
Published: December 2021

Abstract
India’s sustainable development goals consist of higher economic growth through strengthening of the manufacturing sector on the one hand and ambitious carbon emission reduction plans through increased renewables on the other. This paper studies the dynamic association between CO2 emissions, economic growth, renewable energy (RE) consumption and gross capital formation and tests for the existence of Environmental Kuznets Curve (EKC) hypothesis for India over the time period 1970-2018. It also tries to see if there is any possible conflict between the economic and energy goals using an interaction term between RE consumption and gross capital formation. The empirical results not only confirm long run relationship among the underlying variables but also indicate an ‘N’ shaped EKC in the long run for India indicating a departure from the traditional inverted U-shaped EKC hypothesis. RE consumption is found to reduce emissions, whereas gross capital formation and the interaction term between RE consumption and gross capital formation are found to raise emissions in the long run. The study concludes that India needs to align its economic policy of ‘Make in India’ with its energy policy so that investments under the former facilitate extensive penetration, adaptation and usage of renewable energy. A policy dichotomy between the two goals may defeat India’s INDC objective of drastic reduction in CO2 emissions through increased renewables by 2030.
Effect of Different Washing Solutions on Soil Enzyme Activity and Microbial Community in Agricultural Soil Severely Contaminated With Cadmium
Authors: Zhang Yu , Wu Chunfa , Deng Shaopo , Zhang Jinlu , Hou Jinyu , Wang Chong , Fu Zhaocong 
Published: December 2021

Abstract
Soil enzyme activities and microbial communities have a good response to the remediation effect of heavy metal-contaminated soils. To evaluate the effect of three commonly used washing agents, ferric chloride (FC), ethylenediamine-tetra- methylenephosphonic acid (EDTMP) and ethylenediamine tetraacetic acid (EDTA) on soil enzyme activities and microbial community in cadmium (Cd)- contaminated agricultural soil collected around the mining area. The soil enzyme activities, microbial community, chemical forms of Cd and some physicochemical properties of the soil washed with different washing solutions were determined after two months incubation. The results showed that the three washing solutions had moderate removal efficiencies (22.83%-37.56%) for Cd in the tested soil and the breakdown product of EDTMP has a certain stabilizing effect on Cd. The geometric mean and the integrated total enzyme activity index showed that soil washing with FC and EDTA were more beneficial to the restoration of biochemical functions than that with EDTMP. The relative abundance of Gemmatimonadetes in the soil washed with EDTA was significantly higher than that with FC and EDTMP. The relative abundance of Firmicutes in the soil washed with EDTMP was significantly increased, and the relative abundance of Bacteroidetes in the soil washed with FC was significantly decreased. Pearson correlation analysis and redundancy analysis (RDA) indicated that the three washing solutions affected soil enzyme activities and microbial community by altering soil nutrient, total Cd concentration and Cd fractions in soils.