bluuebunny/crossref_metadata_2025_split huggingface dataset:
Justicia restaurativa con personas condenadas por tribunales extranjeros trasladadas a España para cumplir su condena
Authors: Pascual Rodríguez Esther , Etxebarria Zarrabeitia Xabier 
Published: November 2021

Este artículo pretende analizar la viabilidad de la justicia restaurativa en delitos de tráfico de drogas en la fase de ejecución de la pena. Se centra en una experiencia concreta de Justicia Restaurativa con españoles condenados por tribunales extranjeros que han sido trasladados a España para cumplir su pena privativa de libertad por la comisión de delitos contra la salud pública. Dicha experiencia se ha llevado a cabo con el impulso de la Fundación Abogacía Española y la aprobación de la Secretaría General de Instituciones Penitenciarias en el centro penitenciario de Madrid V. Los autores, a su vez, facilitadores del programa analizan la viabilidad de este tipo de justicia en esta tipología delictiva.
Plastic surgery and specialty creep: an analysis of publication trends
Authors: Mackenzie Ethan L. , Larson Jeffrey D. , Poore Samuel O. 
Published: November 2021

Background Many surgical specialties have had pioneering influences from plastic surgeons. However, many of these areas of practice have evolved to include surgeons from diverse training backgrounds. This raises the question as to whether the prominence of other specialties in clinical practice translates to greater research productivity in these areas. The objective of this paper is to investigate the publication volumes of plastic surgeons in selected areas of practice compared to surgeons from other disciplines.
Methods PubMed was used to examine publication trends in areas associated with plastic surgery. Searches for the following topics were performed: head and neck reconstruction, hand surgery, breast reconstruction, ventral hernia repair, abdominal component separation, brachial plexus injury, craniofacial surgery, and aesthetic surgery. Affiliation tags were used to examine contributions from nine specialties. Web of Science was used to identify the top cited articles for the last 10 years in each area.
Results Articles by non-plastic surgeons comprise the majority of the literature for all areas of practice studied except for breast reconstruction and aesthetic surgery. Despite this, plastic surgeons contributed the greatest number of top cited articles over the last 10 years for five of the areas of practice.
Conclusions While plastic surgeons do not contribute the greatest proportion of articles published each year in several of the selected areas of practice, they do publish a larger number of articles that are the most cited. Plastic surgeons remain the dominant academic force in terms of volume and citations for both breast and aesthetic surgery.
Volumetric change of the latissimus dorsi muscle after postoperative chemotherapy and radiotherapy in immediate breast reconstruction with an extended latissimus dorsi musculocutaneous flap: final results from serial studies
Authors: Song Kyeong Ho , Oh Won Seok , Lee Jae Woo , Kim Min Wook , Jeong Dae Kyun , Bae Seong Hwan , Kim Hyun Yul , Jung Youn Joo , Choo Ki Seok , Nam Kyung Jin , Joo Ji Hyeon , Yun Mi Sook , Nam Su Bong 
Published: November 2021

Background Breast reconstruction using an extended latissimus dorsi (eLD) flap can supplement more volume than reconstruction using various local flaps after partial mastectomy, and it is a valuable surgical method since the reconstruction area is not limited. However, when performing reconstruction, the surgeon should consider latissimus dorsi (LD) volume reduction due to postoperative chemotherapy (POCTx) and postoperative radiotherapy (PORTx). To evaluate the effect of POCTx and PORTx on LD volume reduction, the effects of each therapy—both separately and jointly—need to be demonstrated. The present study quantified LD volume reduction in patients who underwent POCTx and PORTx after receiving breast-conserving surgery (BCS) with an eLD flap.
Methods This study included 48 patients who received immediate breast reconstruction using an eLD flap from January 2013 to March 2017, had chest computed tomography (CT) 7–10 days after surgery and 10–14 months after radiotherapy completion, and were observed for more than 3 years postoperatively. One surgeon performed the breast reconstruction procedures, and measurements of breast volume were obtained from axial CT views, using a picture archiving and communication system. A P-value <0.05 was the threshold for statistical significance.
Results The average volume reduction of LD at 10–14 months after completing POCTx and PORTx was 64.5% (range, 42.8%–81.4%) in comparison to the volume measured 7–10 days after surgery. This change was statistically significant (P<0.05).
Conclusions Based on the findings of this study, when harvesting an eLD flap, surgeons should anticipate an average LD volume reduction of 64.5% if chemotherapy and radiotherapy are scheduled after BCS with an eLD flap.
La construcción del arquetipo norteamericano. La imagen cinematográfica y televisiva de Abraham Lincoln en los Estados Unidos
Authors: Mancebo Roca Juan Agustín 
Published: November 2021

El legado histórico de Abraham Lincoln lo ha convertido probablemente en el presidente más importante de los Estados Unidos. Su defensa de la Unión, la abolición de la esclavitud y la Guerra Civil, lo han transformado en el líder esencial para comprender la América contemporánea. Por ello, Lincoln ha sido un referente en la historia del cine norteamericano. Desde las filmaciones tempranas hasta la actualidad, el decimosexto presidente ha constituido un arquetipo representacional asociado a los periodos históricos en los que su figura ha sido reconstruida, vinculada mayoritariamente a tiempos de crisis en los que se refrendaba su carácter mediador y su inteligencia política como modelos de afirmación norteamericana. Lincoln, que había sido capaz de unir y reconciliar a la nación en el periodo más crítico de su joven cronología, se convirtió en el modelo de construcción del mito norteamericano, cuya mención iluminó los periodos oscuros de la Depresión y la Segunda Guerra Mundial. Cuando el país se convirtió en la potencia hegemónica, su figura evolucionó como memoria visual y referente ante los abusos de poder y a las políticas manipuladoras.
The historical legacy of Abraham Lincoln has made him probably the most important U.S. president. His support of the Union, the abolition of slavery and the Civil War have made him the central figure of contemporary American understanding. That is why Lincoln has been a landmark in American film history. From early filming to the present day, the 16th President has been a representational archetype of the historical periods in which his figure has been reconstructed. A figure mainly linked to periods of crisis in which his mediating character and political intelligence were endorsed as models of American affirmation. Lincoln, who had been able to unite and reconcile the nation in the most critical period of its young chronology, became the model for the construction of the American myth. His mention shed light on the dark periods of depression and the Second World War. When his country became the world’s hegemonic power, his figure was transmuted into visual memory as a reference in the face of abuses of power and manipulative policies.
Mettre en oeuvre la Responsabilité Sociale d’Entreprise (RSE) au coeur du business model (BM) : expérimentation d’un processus de création de valeurs au sein de Janssen France
Authors: Gimenes Nathalie 
Published: November 2021

Cet article suggère une nouvelle représentation conceptuelle de la RSE au coeur du BM. La mise en oeuvre de la RSE est traitée sous l’angle d’un processus par lequel les valeurs sociales, sociétales, environnementales et économiques du développement durable sont progressivement incorporées à la stratégie et au BM. C’est en menant une recherche-intervention au sein de Janssen France que trois séquences constitutives de ce processus ont été élaborées et expérimentées. En intégrant la RSE dans sa stratégie et au coeur des composantes du BM, Janssen France élargit la finalité de ses activités et contribue à des objectifs du développement durable.
New Evidence on the Relationship Between Corporate Social Responsibility and the Use of Equity Capital
Authors: Benlemlih Mohammed , Bitar Mohammad , Erragragui Elias , Peillex Jonathan 
Published: November 2021

In this paper, we study the reverse U-shaped relationship between Corporate Social Responsibility (CSR) and firms’ use of equity capital. Using a large sample of U.S. publicly listed companies, we provide strong evidence that CSR is positively associated with the use of equity capital when CSR practices are below a certain level. Once the CSR investment exceeds this level, the relationship between CSR and the equity financing becomes negative. Our findings are robust when we use the individual components of CSR, and several approaches to address endogeneity. Overall, our results enrich the debate about capital structure of high CSR firms and suggest that the CSR-capital structure relationship is more complex than what has been demonstrated in previous literature.
Physician Engagement in Addressing Health-Related Social Needs and Burnout
Authors: Tabata-Kelly Masami , Hu Xiaochu , Dill Michael J. , Alberti Philip M. , Bullock Karen , Crown William , Fair Malika , May Peter , Ortega Pilar , Perloff Jennifer 
Published: December 2024

ImportancePrevious research suggests that a greater capacity of health care organizations to address patients’ health-related social needs (HRSNs) is associated with lower physician burnout. However, individual physician-level engagement in addressing HRSNs has not been fully characterized, and its association with physician burnout remains understudied.ObjectiveTo characterize physicians’ engagement in addressing HRSNs and examine its association with burnout.Design, Setting, and ParticipantsThis cross-sectional study used the 2022 Association of American Medical Colleges National Sample Survey of Physicians (NSSP), a nationally representative survey of active, practicing physicians in the US conducted from May to November 2022 that measured a diverse array of physician workforce characteristics.Main Outcome and MeasuresHRSN engagement was defined by physicians’ responses to the NSSP item, “During the past 12 months, how often did you spend work time helping your patients meet their social needs?” Engagement levels were categorized as no engagement, low to moderate engagement (monthly or &amp;lt;1 time per month), or high engagement (weekly or daily). Burnout was measured using a single-item measure from the emotional exhaustion domain of the Maslach Burnout Inventory (high was defined as weekly or more). HRSN engagement was examined by physician characteristics, and multivariate logistic regression was conducted to explore associations between HRSN engagement and burnout. Data were weighted by age, gender, international medical graduate status, and specialty group.ResultsIn the study cohort of 5447 physicians, the mean (SD) age was 50.9 (11.7) years, and 3735 (68.6%) identified as men or transgender men. Overall, 34.3% of physicians reported high HRSN engagement, with variability based on physician characteristics. Compared with no HRSN engagement, low to moderate HRSN engagement (adjusted odds ratio [AOR], 1.33; 95% CI, 1.03-1.72; P = .03) and high HRSN engagement (AOR, 1.72; 95% CI, 1.39-2.27; P &amp;lt; .001) were significantly associated with high burnout.Conclusions and RelevanceIn this cross-sectional study of 5447 nationally representative physicians in the US, 34.3% regularly dedicated time to addressing HRSNs. The study identified variability in physicians’ engagement in addressing HRSNs and found that higher engagement was associated with a greater likelihood of burnout. The findings suggest the need for thorough assessment of the potential unintended consequences of physicians’ engagement in addressing HRSNs on their well-being.
Biochemical Markers of Acute Coronary Syndromes
Authors: Liu Li , Cao Jing 
Published: December 2024

Abstract
Cardiovascular disease is the most common cause of mortality worldwide and a major public health concern, with the majority of cardiovascular deaths attributable to coronary artery disease. Acute coronary syndrome (ACS) is an ominous manifestation of coronary artery disease and a spectrum of myocardial ischemia ranging from angina with reversible tissue damage to myocardial infarction (MI) with tissue necrosis. Timely and accurate diagnosis of ACS is crucial for initiating early treatment and missed diagnosis may have serious consequences. Biochemical cardiac markers include proteins released from the injured myocardium into the circulation and have long been used for aiding in the diagnosis and risk stratification of ACS. Over the past decades, cardiac biomarkers have evolved greatly from the earlier markers with less myocardium selectivity to later highly cardiac‐specific markers. In addition, the advance in technology has allowed for continuing improvement of analytical sensitivity of cardiac biomarker assays. The increased sensitivity has revolutionized ACS diagnosis by facilitating earlier detection of biomarker rise, shorter time intervals for serial measurements, and faster patient triage in emergency departments.
This chapter describes the current definition of MI and its latest diagnostic guidelines, with a focus on cardiac troponin and the new generation of high‐sensitivity cardiac troponin (hs‐cTn) assays as the preferred cardiac marker. Development of optimal diagnostic algorithms, factors affecting the performance of these algorithms, and alternative diagnostic protocols are discussed. In addition, historical cardiac markers and novel markers with their potential advantages are reviewed.
Proteinivorax
Authors: Kevbrin Vadim V. , Boltyanskaya Yulia V. , Toshchakov Stepan V. , Petrova Kristina O. 
Published: December 2024

Abstract

Pro.te.i.ni.vo'rax. N.L. neut. n.
proteinum,
protein; L. adj.
vorax
, devouring, ravenous, voracious; N.L. neut. n.
Proteinivorax
, protein devouring.

Bacillota / Clostridia / Eubacteriales / Proteinivoracaceae / Proteinivorax

The genus
Proteinivorax
accommodates anaerobic, haloalkaliphilic bacteria, which are specialized in the degradation of proteins and proteinaceous compounds. Cells stain Gram positive, and are anaerobic, mostly non‐motile, polymorphic, straight or slightly curved rods, which are prone to polymorphism, occur singly or in pairs, and reproduce by binary fission. Sporulation is variable. Chemoorganotrophic, mostly fermentative but capable of reducing fumarate, thiosulfate, sulfur, and DMSO (variable). Preferable substrates are proteins, partially hydrolyzed proteinaceous compounds, and ribonucleosides in the presence of tryptone. The main products of tryptone degradation are acetate, ammonium and, depending on species, formate and hydrogen as well. The major fatty acids are iso‐C
15:0
, anteiso‐C
15:0
, and C
16:0
. Known habitats are sediments of haloalkaline lakes and alkaline bioreactors for wastewater treatment or biogas production.

DNA G + C content (mol%)
: 35.0–37.0 (genome sequence).

Type species
:
Proteinivorax tanatarense
Kevbrin et al. 2013, VL155.
Lysozyme/Tracheal Antimicrobial Peptide‐Based Tissue‐Specific Expression Antimicrobial Plasmids Show Broad‐Spectrum Antibacterial Activities in the Treatment of Mastitis in Mice
Authors: Yang Yi , Meng Yining , Chen Daijie , Hou Ping , Zhang Zhipeng , Cao Wenqiang , Meng Ye , Zhang Qianwen , Tu Runyan , Hao Xiaoli , Qin Aijian , Shang Shaobin , Yang Zhangping 
Published: December 2024

AbstractThe use of antibiotics is the preferred therapy for bacterial diseases. However, overusing antibiotics has led to the development of antibiotic resistance in bacteria, which is now a major public health concern. Therefore, in this study, the performance of lysozyme (LYZ)/tracheal antimicrobial peptide (TAP)–based tissue‐specific expression antimicrobial plasmids (TSEAP) have been evaluated in the treatment of mastitis in mice. The results show that LYZ/ and TAP‐based TSEAP could effectively reduce the clinical symptoms caused by Staphylococcus sciuri, Bacillus cereus, Escherichia coli, and Pseudomonas aeruginosa–induced mastitis. In addition, the studies of behavioral tests, parameters of weight growth, blood biochemistry, and organ coefficients comprehensively indicate that the transfection of LYZ/TAP‐based TSEAP is safe in mice. Taken together, LYZ/TAP‐based TSEAP have broad‐spectrum antibacterial activity and may provide new insight for the non‐antibiotic treatment of bacterial diseases.
A pH‐Responsive, Surface Charge‐Switchable Nanosystem with Enhanced Biofilm Penetration for Synergistic Photodynamic and Antibiotic Therapy of Diabetic Wounds
Authors: Sun Zhencheng , Xiao Minghui , Lv Shuyi , Wang Cheng , Fu Hao , Tian Liang , Shi Linqi , Zhu Chunlei 
Published: December 2024

AbstractChronic wounds, particularly those associated with diabetes, pose a significant clinical challenge due to their tendency to develop biofilms that resist conventional antibiotic treatments. To address this issue, a novel therapeutic strategy utilizing pH‐responsive nanoparticles loaded with aggregation‐induced emission photosensitizers and natural saturated fatty acids (AIE/LA@HMONs−PyB) for effective biofilm penetration and disruption is proposed. Under physiological conditions, AIE/LA@HMONs−PyB are negatively charged. Upon accumulation at infected sites, however, the pyridine betaine group on the surface of AIE/LA@HMONs−PyB enables rapid protonation and charge reversal in the acidic biofilm microenvironment, thereby enhancing their ability to penetrate the biofilm. Upon light irradiation, these nanoparticles generate reactive oxygen species that effectively disrupt the biofilm structure. This process enables the synergistic action of ciprofloxacin at a lower concentration, achieving an exceptional in vitro antibacterial efficiency of 99.99% against methicillin‐resistant Staphylococcus aureus (S. aureus) biofilms. Furthermore, in an in vivo diabetic wound model, this synergistic therapy accelerates wound healing by reducing inflammation, promoting angiogenesis, and enhancing collagen regeneration. The enhanced penetration strategy significantly improves the therapeutic efficacy of this combined approach, offering great promise for advancing chronic wound healing and enhancing patient outcomes.
Boronophenylalanine‐Functionalized Platinum Nanozymes Sensitizing Neutron Capture Therapy
Authors: Li Xiangxia , Chen Guiyuan , Hong Bing , Guo Changqing , Zhu Huanjun , Zhu Qilong , Liu Yuanyu , Li Zilong , Li Lingling , Gao Chao , Lu Peng , Qian Dong , Liang Lizhen , Xiong Yujie , Min Yuanzeng 
Published: December 2024

AbstractBoron neutron capture therapy (BNCT), which uses high‐energy particles generated by the reaction of 10B isotope with thermal neutrons to kill tumor cells precisely at the microscale, has become a promising treatment approach with aggressive and recurrent cancers. The development of highly selective boron drugs for tumor cells and devices with thermal neutron beams is crucial for BNCT. Borophenylalanine (BPA), the most widely used 10B containing drug in clinic, has problems with fast metabolism and poor tumor retention. Therefore, to improve the therapeutic effect of BPA, this study reports highly 10BPA‐loaded platinum nanoparticles (Pt‐10BPA NPs) and conduct BNCT experiments with a neutron beam generated by an accelerator neutron source. The Pt‐10BPA NPs achieve deep tumor penetration and retention, thereby significantly inhibiting the growth of subcutaneous colorectal tumors in mice. Furthermore, unlike classic drugs, the Pt‐10BPA NPs have superior catalytic properties and can sensitize BNCT by increasing reactive oxygen species (ROS) production. Since the observation of improvements in immune responses induced by Pt‐10BPA NPs sensitized BNCT, its further combination with immune checkpoint blockade therapy results in significant suppression of both primary and secondary tumors. In summary, this study provides a new aspect for the development of catalytic nanomedicines for BNCT sensitization.
Toward Efficient and Stable Ruddlesden‐Popper Perovskite: Unraveling the Selection Rule of Binary Spacer Cations
Authors: Li Shenghong , Wu Yi , Zhong Jun , Tian Wei , Li Liang 
Published: December 2024

Abstract2D Ruddlesden‐Popper (RP) perovskites have excellent environmental stability and enhanced photostability compared with their 3D counterparts. However, the introduction of organic spacer cations induces disordered crystal growth and increased exciton binding energy, limiting the photoelectric performance. Here, a binary spacer cations engineering strategy is reported that incorporates aromatic and alkylamine spacer cations, in which fluorine‐substituted hydrocarbons (4‐TFBZAI) promotes carrier transport and alkylamine (BAI) assists the ordered growth of perovskite. The resulting binary spacer perovskite (4‐TFBZA1.6BA0.4)FA4Pb5I16 shows preferred orientational growth and reduced exciton binding energy, enabling an efficient photodetector with a detectivity exceeding 1013 Jones and a response time of 583 ns. The influence of the spacer cations with varying functional groups and chain lengths is examined. The results reveal that selecting long‐chain alkylamine to mix with aromatic spacer cations shall be based on considerations of both functional groups and chain length. The aromatic spacer cation with suitable groups enhances carrier transport, while the flexible long‐chain alkylamine facilitates perovskite crystal growth. Moreover, matched chain lengths between aromatic and alkylamine spacer cations are crucial to the photoelectric performance of RP perovskites. This work will guide researchers in selecting suitable binary spacer cations and designing new types of RP perovskites.
Nickel‐Based Hollow Spheres with Optimized Interfacial Electronic Structures by Highly Dispersed MoN for Efficient Urea Electrolysis
Authors: Fan Yuying , Li Zhihui , Liu Yue , Liu Jianan , Wang Dongxu , Yan Haijing , Gubanov Aleksandr I. , Wu Aiping , Tian Chungui 
Published: December 2024

AbstractNi‐Mo‐based catalysts that exhibit well‐synergized and readily accessible catalytic sites are ideal catalysts for achieving efficient electrocatalysis. Herein, the synthesis of hollow Ni spheres with a hierarchical nanosheet surface modified by highly dispersed MoN for efficient urea electrolysis is reported. This synthesis is based on the design of hollow Mo‐Ni precursors featuring a nanosheet array surface, achieved through the phosphomolybdic acid (PMo12)‐mediated reconstruction of hollow Ni‐BTC spheres. The optimized MoN‐Ni catalyst can effectively drive both the urea oxidation reaction (UOR) and hydrogen evolution reaction at low potentials of 1.37 V and 191 mV, respectively, achieving a current density of 100 mA cm−2. The electrolytic cell utilizing these catalysts can sustain 100 mA cm−2 at a low voltage of 1.53 V and can operate continuously for over 220 h. The X‐ray photoelectron spectroscopy (XPS) and density functional theory (DFT) analyses demonstrate the established built‐in electric field facilitates electron transfer from MoN to Ni, optimizing the d‐band center and consequently reducing the reaction barrier for the UOR. In situ electrochemical impedance spectroscopy (EIS) and in situ Fourier‐transform infrared spectroscopy analyses indicate that MoN promotes the formation of high‐valent Ni sites, which accelerates the UOR and facilitates the urea eletrolysis through a more environmentally friendly “carbonate” pathway.