bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gastrointestinal stromal tumor experience in a surgical oncological unit in sub-Saharan Africa
Authors: Ayandipo Omobolaji O. , Ogun Gabriel O. , Ajagbe Oluwasanmi A. , Adegoke Omolade O. , Adepoju Olalekan J. , Rahman Adam , Ajuyah Chioma M. , Orunmuyi Akintunde T. , Shittu Olayiwola B. 
Published: April 2021

Background:
Gastrointestinal stromal tumors (GISTs) are characterized by specific immunohistochemical and genetic features. This study investigated the clinicopathologic features and surgical outcomes of 54 patients with GIST in a major referral hospital in sub-Sahara Africa.

Methods:
This retrospective cross-sectional single-center study describes 54 patients who underwent surgery for GIST between 1999 and 2019 in a Nigerian Tertiary Hospital. All cases were confirmed by immunohistochemistry and were analyzed for clinical characteristics, clinical management, and histopathologic data. The risk of recurrence was determined using the Fletcher National Institutes of Health criteria.

Results:
The mean age of the patients was 57.6 years ± 15.3 (11–81 years), and most patients (67%) underwent abdominal computed tomography scans preoperatively. The most common presentation was an abdominal mass (48%). The stomach was the most common site of GIST (37%). The mean tumor size was 8.9 cm (5–18 cm), and tumor morphology showed spindle cell type (75.9%), mixed spindled-epithelioid (20.3%), and epithelioid (3.7%) cell types. Overall, 51% had a high risk for recurrence.

Conclusion:
The clinicopathologic features of GIST in this study are consistent with reports in the literature. Slight variations in risk profile may be due to late presentation in our settings.
Left Ventricular Function Assessment of Patients with Postoperative Ventricular Septal Defect Closure by Longitudinal Strain on Two-Dimensional Echocardiography 1 Year after Surgery
Authors: Banpurkar Ashish , Azad Sushil , Radhakrishnan Sitaraman , Garg Ankit 
Published: April 2021

Background:
Patients with large perimembranous ventricular septal defects (pm-VSDs) undergo surgical repair with prosthetic material during infancy. However, the effect of the presence of akinetic patch in the ventricular septum on the left ventricular (LV) mechanical synchrony and ventricular function has not been studied. In our study, we assessed LV function in postoperative pm-VSD closure patients on two-dimensional (2D) echocardiography (echo) after 1 year of surgery using biplane Simspon's method, fractional shortening (FS), and global longitudinal strain (GLS) to assess the regional strain pattern.

Methods:
This was a a single-institution observational study. Patients following up 1 year after surgical ventricular septal defect closure at our institute were enrolled. On follow-up, detailed 2D echo was done with special emphasis on left atrial size, LV size (by M-mode), and presence of any residual shunt. LV function was assessed using biplane Simpson's method and longitudinal strain on 2D echo. GLS was measured in three standard apical views.

Results:
Of the 121 patients enrolled, 101 patients fulfilling the inclusion and exclusion criteria were analyzed. Of these 101 patients, 75.2% were males. The median age at follow-up after surgery was 3.67 ± 2.7 years. About 92.1% of patients did not have residual VSD lesion. No patient had pulmonary arterial hypertension. All except one patient had normal ventricular function. Patients with ventricular dysfunction had LV ejection fraction (LVEF) of 47%, GLS –17.4%, and FS −20.5%. The mean values of FS, LVEF, and GLS were 32.0 ± 5.28%, 62.2% ± 4.2%, and −26.53 ± 2.93%, respectively, in pm-VSD closure patients. Regional strain pattern analysis showed significantly lower strain values in basal anteroseptal segment with a mean of −21.4 ± 2.7%. FS and GLS were noted to have significant correlation with each other (P = 0.01) and LVEF by biplane Simpson's method and GLS had significant correlation with each other (P = 0.0001).

Conclusions:
GLS has strong correlation with LVEF by Simson's method and FS. Basal anteroseptal segment in pm-VSD patients had significantly lower strain values compared to other segments. There is no significant correlation between age at surgery and GLS in pm-VSD closure patients who were operated within 1 year of age. The type of VSD closure does not have significant influence on GLS.
Video-assisted thoracoscopic surgery management of primary spontaneous pneumothorax
Authors: Puri Harsh Vardhan , Asaf Belal Bin , Pulle Mohan Venkatesh , Bishnoi Sukhram , Kumar Arvind 
Published: April 2021

Background:
Primary spontaneous pneumothorax (PSP) results from the rupture of small blebs or bullae in a patient without any pre-existing lung disease. Last decade witnessed a paradigm shift in the surgical management of pneumothorax from open to video-assisted thoracoscopic surgery (VATS) method. In this study, we aim to report our single center experience of surgical management of PSP along with surgical outcomes in 110 consecutive cases of PSP.

Materials and Methods:
This is a retrospective study of 110 operated cases of PSP over 5 years. Demography, computed tomography findings, operative technique, endoscopic classification (Vanderschueren), surgical duration, intraoperative and postoperative complications, duration of Intercostal Drain (ICD), hospital stay, and recurrence in follow-up were recorded.

Results:
The average age of patients was 27.59 years (range 9–68 years). The average number of episodes before the presentation was 2 (range 1–5). The average number of loss of working days because of symptoms, conservative management, or long-term intercostal drainage was 13.33 days (range 5–60 days). As per intra-operative findings, patients were categorized as per Vanderschueren's classification and managed accordingly. Conversion rate was in 1.8% (n = 2). Mean time to removal of chest tubes was 4 days (2–12 days). Mean hospital stay was 3.83 days (2–9 days). There were no postoperative deaths. The mean follow-up was 25.05 months (6–60 months). Overall complication rate was 3.6% (n = 4) and recurrence happened in 2.7% (n = 3) cases.

Conclusions:
VATS is an efficient and safe treatment modality for PSP with low recurrence rates and high level of patient satisfaction.
MEDIA PEMBELAJARAN DI SMK SWASTA MELYAZ CINTA RAKYAT
Authors: Sadanah Meila Nida , Rusydi Rusydi , Zulham Zulham 
Published: April 2021

Abstrak-Media berfungsi sebagai sarana pembelajaran individual yang membuat kedudukan, media juga dapat memfasilitasi kebutuhan belajar peserta didik secara mandiri. Pemakaian media pengajaran dalam proses belajar mengajar dapat membangkitkan keinginan dan minat yang baru, membangkitkan motivasi dan rangsangan kegiatan belajar. Selama melakukan penelitian di SMK Swasta Melyaz Cinta Rakyat, peneliti menemukan masalah sistem pada bagian proses pembelajaran di TSM (Teknik Sepeda Motor) biasanya untuk sebuah teori dilakukan di kelas dan untuk pratikum dilakukan di bengkel, berhubung pada saat ini lagi pandemi covid-19, siswa dilarang belajar antar tatap muka jadi siswa belajar melalui daring (online). Siswa pun jadi sulit untuk memahami teori tersebut karena terbiasa belajar secara langsung di bengkel tersebut. Oleh karena itu maka penulis mengusulkan suatu sistem media pembelajaran untuk jurusan TSM (Teknik Sepeda Motor) yang menggunakan Vb.Net untuk teori kelistrikan sepeda motor. Dengan adanya media pembelajaran ini maka siswa semakin mudah untuk memahami mata pelajaran tersebut. Hasil dari penelitian adalah sistem media pembelajaran kelistrikan sepeda motor yang dapat digunakan siswa untuk belajar dan digunakan guru untuk melakukan evaluasi dengan media pembelajaran. Kata Kunci : Sistem, Media Pembelajaran, Kelistrikan Sepeda Motor, Visual Basic
Pengaruh Lingkungan Kerja, Stres Kerja, Pengawasan terhadap Semangat Kerja Karyawan (Studi pada CV. Bintang Tex Indonesia-Tulangan Sidoarjo)
Authors: Dewi Nafalina Sitta , Rosyafah Siti , Noviandari Indah 
Published: April 2021

Ada beberapa faktor yang dapat mempengaruhi semangat kerja karyawan antara lain: lingkungan kerja, stres kerja dan pengawasan. Penelitian ini bertujuan untuk mengetahui dan membuktikan pengaruh lingkungan kerja, stres kerja, pengawasan terhadap semangat kerja karyawan (studi pada CV. Bintang Tex Indonesia-Tulangan Sidoarjo), secara simultan maupun parsial. Hasil penelitian menunjukan bahwa: lingkungan kerja, stress kerja dan pengawasan berpengaruh positif terhadap semangat kerja hal ini dibuktikan dengan nilai Fhitung> Ftabel (109.945 > 2,76) dan nilai signifikansi Fhitung sebesar 0,000. Lingkungan kerja berpengaruh positif terhadap semangat kerja hal ini dibuktikan dengan nilai thitung> ttabel (9.507 > 2.003) dan nilai signifikansi sebesar 0,000 < 0,05, stress kerja berpengaruh negative terhadap semangat kerja hal ini dibuktikan dengan nilai thitung> ttabel (-3.183 > 2.003) dan nilai signifikansi sebesar 0,002 < 0,05, pengawasan berpengaruh positif terhadap semangat kerja hal ini dibuktikan dengan nilai thitung> ttabel (3.276 > 2.003) dan nilai signifikansi sebesar 0,002 < 0,05. Lingkungan Kerja berpengaruh secara dominan terhadap Semangat Kerja Karyawan, hal ini dibuktikan oleh besarnya nilai 0,701 pada hasil pengujian parsial (uji t) nilai beta tertinggi.
Omega-6 fatty acids and the Risk of Cardiovascular Disease: Insights from a Systematic Review and Meta-Analysis of Randomized Controlled Trials and a Mendelian Randomization Study.
Authors: Mazidi Mohsen , Shekoohi Niloofar , Katsiki Niki , Banach Maciej , Meta-analysis Collaboration (LBPMC) Group the Lipid and Blood Pressure 
Published: April 2021

IntroductionThe effects of omega-6 PUFAs on the CV risk factors are still controversial. Thus, we performed a systematic review and meta-analysis of RCTs as well as a Mendelian Randomization analysis to evaluate the links and possible causality between omega-6 PUFA, CVD and cardiometabolic risk factors.Material and methodsSelected databases were searched until September 2019 to identify prospective studies investigating the effects of omega-6 PUFAs supplementation on CVD events/mortality. Random-effects model meta-analysis was performed for quantitative data synthesis. Trial sequential analysis (TSA) was used to evaluate the optimal sample size to detect a 20% reduction in outcomes after administration of omega-6 PUFAs. Inverse variance weighted method (IVW), weighted median-based method, MR-Egger and MR-PRESSO were applied for MR.ResultsThe pooled estimate risk ratio (RR) of omega-6 PUFAs supplementation was 0.94 for any CVD event (95%CI:0.77-1.15, I2=66.2%), 1.06 for CVD death (95%CI:0.73-1.55, I2=66.2%), 0.84 for coronary heart disease (CHD) events (95%CI:0.61-1.16, I2=79.4%), 0.87 for myocardial infarction (MI) (95%CI:0.74-1.01, I2=2.3%) and 1.36 for stroke (95%CI:0.45-4.07, I2=55.3%). In contrast, MR showed that individuals with higher serum adrenic acid (AA) levels had a greater risk for CHD events (IVW=Beta:0.526), MI (IVW=Beta:0.606) and large artery stroke (IVW=Beta:1.694), as well as increased levels of FBG (IVW=Beta:0.417), LDL-C (IVW=Beta:0.806,) HDL-C (IVW=Beta:0.820), and lower levels of triglycerides (TG) (IVW=Beta:-1.064) and total cholesterol (TC) (IVW=Beta:-1.064).ConclusionsOmega-6 PUFAs supplementation did not affect the risk for CVD morbidity and mortality. Additionally, in MR analysis we showed that higher AA levels might even significantly increase with the risk of CHD, MI and large artery stroke.
Sistem Pengelolahan Data Surat Masuk dan Surat Keluar Kelurahan Curug
Authors: Mardiyati Sri 
Published: April 2021

An accurate and efficient application of incoming and outgoing report reports at the Curug Kelurahan Office, making an effective and efficient application of incoming and outgoing mail management in accordance with the needs of the Curug Kelurahan office, making applications that facilitate administration in mail management, making incoming mail applications and the user's outgoing mail, making an application for incoming and outgoing mail that is easily used by the user. The research method used to design this data processing application is the method of library study, observation and interviews to get more complete data. After the author designs and makes this data processing application, the writer can draw the conclusion that with this application can provide solutions in helping Curug Kelurahan in recording incoming and outgoing letters, with the application already made, the duties of the Administration and Secretary of the Village Head can be easier and better recorded because it is assisted by a computerized system.
Keywords: System Design, Data Processing, Incoming and Outgoing
Sistem Informasi Layanan Pengaduan Kerusakan Jalan Berbasis Geographic Information System
Authors: Warjiyono Warjiyono , Faiqoturrohmah Hilda , Aji Sopian 
Published: April 2021

Undang-Undang Republik Indonesia No. 22 Tahun 2009 Tentang Lalu Lintas Dan Angkutan Jalan menyatakan bahwa prasarana lalu lintas dan angkutan jalan adalah ruang lalu lintas, terminal, dan perlengkapan jalan yang meliputi marka, rambu, alat pemberi isyarat lalu lintas, alat pengendali, dan pengamanan pengguna jalan, alat pengawasan dan pengamanan jalan, serta fasilitas pendukung. Dinas Perhubungan kesulitan dalam memantau titik rambu lalu lintas yang tersebar di wilayah Kabupaten Tegal. Masyarakat juga kesulitan dalam mengadukan atau melaporkan adanya kerusakan jalan dan prasarana lalu lintas karena lewat telepon sehingga kurang cepat dan sulit menentukan titik lokasinya. Perlunya media online untuk segera melakukan pengaduan terhadap jalan rusak atau prasaran lalu lintas lainnya yang perlu disampaikan kepada Dinas Perhubungan Kabupaten Tegal agar segera diperbaiki. Penelitian ini merancang dan membangun sistem informasi geografis layanan aduan jalan berbasis website. Metode pengembangan perangkat lunak menggunakan Extreme Programming (XP). Metode penelitian mengunakan metode kualitatif dengan teknik analisis data deksriptif. Data diperoleh dengan observasi dan wawancara. Manfaat dari aplikasi ini adalah untuk meningkatkan pelayanan pengaduan masyarakat agar menjadi lebih efektif, efesien, cepat dan transparan.
Pengukuran Maturity Level Tata Kelola Teknologi Informasi Menggunakan Framework Cobit 4.1 Pada Pt. Dinamika Mitra Sukses Makmur
Authors: Dazki Erick , Islami Zaenab , Atmojo Wahyu Tisno 
Published: April 2021

Suatu organisasi atau perusahaan saat ini pasti menggunakan Teknologi Informasi dan Komunikasi yang kompleks bahkan menjadi core bisnis pada perusahaan tersebut. Teknologi informasi secara signifikan telah mempengaruhi dan mengubah cara mengelola bisnis, oleh karena itu diperlukan tata kelola yang baik serta pengelolaan terhadap teknologi informasi bertujuan untuk memastikan Teknologi Informasi dapat selalu mendukung bisnis, oleh sebab itu Teknologi Informasi harus diimpelentasikan secara optimal, efektif dan efisien. Tata kelola pada PT. Dinamika Mitra Sukses Makmur menggunakan Cobit 4.1 yaitu PO1, PO10, DS4, AI1, ME2. Hasil evaluasi dari penelitian terhadap PT. Dinamika Mitra Sukses Makmur menunjukan tingkat kematangan berada pada nilai 2.82 pada ME2 dan tingkat kelemahan berada pada nilai 2.40 pada PO1 dan PO10. Pada penelitian ini menunjukan bahwa Tata Kelola Teknologi Informasi pada PT. Dinamika Mitra Sukses Makmur sudah pada nilai Defined Process. Perbaikan utama yang harus ditingkatkan yaitu pada Plan and Organise / Perencanaan dan Pengorganisasian pada PT. Dinamika Mitra Sukses Makmur.
Aplikasi Pengukuran Tingkat Kepuasan Mahasiswa Terhadap Layanan Akademik Menggunakan Metode IPA (IMPORTANCE PERFORMANCE ANALYSIS)
Authors: Lubis Ihsan , Lubis Husni , Mita Febri Dhea 
Published: April 2021

Universitas sangat berperan penting dalam memberikan layanan pendidikan kepada mahasiswa, bentuk dan jenis layanan yang diberikan oleh pengelolah lembaga pendidikan tinggi tersebut harus sesuai dengan kepuasan mahasiswa didalam lembaga pendidikan tinggi. Kualitas berkaitan dengan seberapa baik layanan yang diberikan dapat memenuhi harapan pengguna. Sistem pelayanan akademik merupakan salah satu jenis layanan yang diberikan selain dari layanan fasilitas, layanan karir, layanan kesehatan dan beberapa layanan yang diberikan, yang ada pada sebuah Universitas. Metode Importance Performance Analysis dapat mengukur tingkat kepuasan pelayanan serta mengukur tingkat kesesuaian untuk mengetahui seberapa besar Mahasiswa merasa puas terhadap kinerja Universitas.

Kata kunci— Universitas, Layanan, Kualitas, Akademik, Importance Performance Analysis
Rancang bangun Sistem Informasi Manajemen Asset berbasis WEB
Authors: Sudrajat Budi 
Published: April 2021

Manajemen Asset adalah pengelolaan asset (kekayaan) dari perusahaan untuk memonitor dan menghitung juga memanfaatkannya secara optimal. Sedangkan fungsi dari manajemen asset merupakan informasi perjalanan asset secara menyeluruh, memuat berapa banyak asset, pemanfaatan, kondisi dan pemeliharaannya. Dalam rancang bangun aplikasi ini meyajikan data asset perusahaan yang terdiri dari pengadaan barang, mutasi asset, peminjaman asset dan penghapusan asset. Penelitian manajemen asset dilakukan pada tahap perencanaan, pengadaan, penerimaan dan laporan. Penelitian ini mengahsilkan prototype system yang menghasilkan fungsionalitas perencanaan, pengadaan, penerimaan dan laporan. Metode yang digunakan adalah pendekatan berorientasi objek dengan menggunakan UML (Unified Modeling Language) yakni use case diagram dan activity diagram serta ERD (entity relationship diagram) dan software architecture. Penelitian ini menghasilkan sebuah prototype yang dapat di implementasikan lebih lanjut sehingga menghasilkan sebuah sistem informasi manajemen asset dengan menggunakan fitur menu aplikasi yang berguna bagi perusahaan. Aplikasi dibuat dengan menggunakan bahasa pemrograman PHP, interface dikembangkan dari framework CSS serta databasenya menggunakan MySql.
Analisis Tata Kelola It Menggunakan Framework Cobit 5 Pada Domain Monitor, Evaluate And Assess (Mea)
Authors: Sivadjati Bram , Sofian Thamrin , Achmad Zulfikar Ferdy , Eko Indrajit Richardus , Dazki Erick 
Published: April 2021

Nowadays information and technology (IT) plays an important role in the organization in order to support the organization to be more productive and as a result become advanced organization. In fact, the organizations like; logistic, education and shopping center have used IT to support their business system. However, as a matter of fact the use of the IT in their organizations still need in-depth evaluation. Therefore, COBIT framework version 5 will be used in this study in evaluating with the intention of gathering some information about IT govermance in related industries especially in MEA (Monitor, Evaluate, and Assess) domain. The result of the evaluation can be used as a recommendation of each industries to have a better IT govermance in the future.
¿Hay algo que los planes puedan hacer por la teoría del derecho?
Authors: Celano Bruno 
Published: April 2021

En su libro, Legalidad, Scott Shapiro afirma ofrecer una respuesta, “nueva que, con suerte, será mejor” (es decir, mejor de las que han sido ofrecidas hasta el momento), a la pregunta fundamental ‘¿qué es el derecho?’. La tesis central de esta nueva explicación –la tesis de los planes– es que la actividad jurídica es una forma de planificación social: “Las instituciones jurídicas planifican para las comunidades sobre las que pretenden tener autoridad, tanto diciendo a sus miembros qué pueden, o no pueden, hacer, como identificando quiénes tienen derecho a afectar lo que otros pueden o no hacer”. La noción relevante de planes es la noción moldeada, en la filosofía de la acción, por Bratman. Según Shapiro, este enfoque hace posible un progreso sustancial en la teoría del derecho. ¿Qué pueden hacer los planes (bratmanianos) para la teoría del derecho? ¿Recurrir al concepto de plan de Bratman, tal como propone hacerlo Shapiro, brinda efectivamente una nueva y especial visión de la naturaleza del derecho? Mi argumento es que la respuesta es negativa.
Una mirada positivista a los desacuerdos teóricos
Authors: Ferrer Beltrán Jordi , Ratti Giovanni Battista 
Published: April 2021

Los autores analizan las partes de Legalidad que abordan el problema de los desacuerdos jurídicos y la conexa teoría de la interpretación (y metainterpretación) desplegada por Shapiro con el fin de superar tal dificultad. La cuestión de los desacuerdos jurídicos, junto con las principales asunciones del positivismo jurídico, hace necesario, de acuerdo con los autores, prestar cierta atención a las versiones contemporáneas de tal concepción teórico-jurídica. En consecuencia, la estructura del artículo es la siguiente: en el primer párrafo, se trata el positivismo en el modo en que normalmente es explicado en la teoría del derecho angloamericana; en el segundo párrafo, los autores presentan su propia explicación del positivismo jurídico metodológico, deudora en gran medida de las obras de Bobbio y Ross; en el tercer párrafo, se resume el argumento de los desacuerdos y se analizan atentamente las dificultades que supuestamente plantea al positivismo jurídico; esto lleva al cuarto párrafo, donde la concepción de Shapiro de la interpretación jurídica y su consiguiente respuesta a semejante desafío son examinadas; en el quinto y último párrafo, se extraen algunas conclusiones, siendo la principal de ellas que la sofisticada teoría de la interpretación de Shapiro es, por un lado, supererogatoria y, por otro, infiel al auténtico espíritu del positivismo metodológico tradicional, al mezclar aspectos descriptivos y prescriptivos de la interpretación jurídica.
COVID-19 E VIDA IDOSA
Authors: Santos Paulo Rodrigues dos 
Published: April 2021

O texto objetiva contribuir para a compreensão do por que da pandemia da SARS Cov 2 travar o mundo capitalista, com base em tríplice recorte: a) – delineamento da vulnerabilidade biológica da população mundial frente à pandemia, com ênfase na condição idosa, na descrição de um conjunto de afecções não transmissíveis, de predominância global e na desnaturalização do óbito, por Covid-19, na velhice; b) - análise da hipótese de que tais enfermidades resultam de racionalidades econômicas e políticas de base medicamentosa e alimentar, que conformam um tipo de governo populacional global, uma biopolítica da “saúde”; c) - descrição do campo medicinal compartido em: “medicina da doença”, que atua com cerca de dois terços da população; “medicina da saúde”, com ação sobre, aproximadamente, um terço da população. Ambas com condição legal constituem domínios econômicos financeiros da economia mundial, duas linhas da medicina oficial implicadas na saúde como negócio. O texto articula metodologia quantitativa e qualitativa e tem suporte nas formulações teóricas de Michel Foucault.
INFLUÊNCIAS ACERCA DA COVID-19 ENTRECORTADAS PELAS INTERFACES DA HIPERMODERNIDADE NA FACULDADE DE PEDAGOGIA DA UNIRV
Authors: Quinteiro José Reinaldo Araújo , Silva Rosimeire Soares da 
Published: April 2021

A educação não consiste em um advento fora da sociedade, pois está imbricada em todas as esferas das relações humanas. Nessa via, este artigo visa apresentar como ocorreu a adesão ao ensino não presencial na educação superior goiana frente ao distanciamento social e a reinvenção da prática pedagógica na sociedade hipermoderna, tomando como âncora de estudo a Faculdade de Pedagogia da UniRV. Para tanto, questiona-se: Como a hipermodernidade se materializa na educação na educação superior goiana? Quais são as influências acerca da Covid-19 entrecortadas pelas interfaces hipermodernas para a reinvenção da prática pedagógica frente ao distanciamento social de 2020? Como reagiram os sujeitos da educação superior? No que tange à metodologia de pesquisa, busca-se, na relação com o objeto, descrever quais são esses processos e influências na instituição observada. Os procedimentos técnicos, deste estudo, são pautados em: documentos que regimentaram o distanciamento social em Goiás, além de leituras bibliográficas por meio das quais se alude ao conceito de sociedade hipermoderna e, por fim, ex-post-facto com vistas aclarar como a faculdade incorporou a aula não presencial em momento de crise sanitária.