bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of shortages of opioid analgesics in the US: Are the characteristics of the drug company the missing puzzle piece?
Authors: Rodriguez-Monguio Rosa , Naveed Mahim , Seoane-Vazquez Enrique 
Published: March 2021

Background
Shortages of opioid analgesics are increasingly common, interfere with patient care and increase healthcare cost. This study characterized the incidence of shortages of opioid analgesics in the period 2015–2019 and evaluated potential predictors to forecast the risk of shortages.

Methods
This was an observational retrospective study using the US Food and Drug Administration (FDA) drug shortages data. All FDA approved opioids were included in the study. Opioid analgesics were identified using the FDA National Drug Codes (NDC) and classified according to the Drug Enforcement Administration (DEA) schedule. We conducted Least Absolute Shrinkage and Selection Operator logistic regression analysis to assess direction of the association between risk of shortage and potential predictors. We used multivariable penalized logistic regression analysis to model predictors of shortages. We split the dataset into training and validation sets to evaluate the performance of the model.

Findings
The FDA approved 8,207 unique NDCs for opioid analgesics; 3,017 (36.8%) were in the market as of April 30, 2019 and 91(3.0%) of them were listed as in shortage by the FDA. All NDCs in shortage were schedule II opioids; 86 (94.5%) were injectable and 84 (92.3%) generics. There were 418 companies with at least one opioid NDC listed by the FDA. Three companies accounted for more than 4 in 5 of the schedule II active injectable opioids. For each unit increase in the number of prior instances of shortages of a company, the likelihood of an NDC shortage for that company increased by 3.4%. For each unit increase in number of NDCs marketed by a company, the odds of an NDC shortage for that company decreased by 1%.

Conclusions
In the period 2015–2019, shortages of opioid analgesics disproportionally impacted schedule II and injectable opioids. The risk of shortage of opioid analgesics significantly increased with the incidence of previous instances of shortages of a manufacturing company and decreased with the number of NDCs marketed by a company. The characteristics of the manufacturing company, rather than the number of companies, might be the missing piece to the complex puzzle of drug shortages in the US.
Editorial n.70 v.34 Jan./Abr. 2020
Authors: Silveira Fillipa Carneiro 
Published: March 2021

Nosso número 70 traz uma série de reflexões que tocam cruzamentos entre a Filosofia, a Educação e, neles, um sentido de formação que, de alguma maneira, reúne em comum essas duas regiões do saber. Aliás, é sobretudo em torno desse sentido de comum, para além do domínio do conhecimento, mobilizando densas questões de ordem moral e política, que o dossiê Governo das diferenças e as cartografias do ingovernável na educação: entre a arte e a política, organizado pelos professores Pedro Ângelo Pagni e Divino José da Silva, nos conduz entre os inúmeros desafios do Mesmo e da Diferença. Aproveitamos para convidar à leitura de sua apresentação!
Nesse momento em que nos movemos, em um mundo que usávamos “partilhar” por meio da informação, e que vemos agora experienciado em comum pela presença global de uma ameaça invisível e pela intensificação de práticas de recusa da diferença: sucumbimos ou resistimos? Que controvérsias produtoras, resistências e afirmações somos capazes de sustentar? Diante do conflito entre uma tradição que nos formou, ao mesmo tempo em que cristalizava preconceitos e privilégios, e os esforços emancipatórios que clamam por diferença e equidade ética, política e material: o que pode nos oferecer o pensamento?
Ele diz respeito ao que nos fortalece diante da experiência oscilante entre o medo e o enfrentamento, ao entrecruzamento mesmo entre o “pessimismo da inteligência” e o “otimismo da vontade” gramscianos. É nele que podemos sustentar o desafio do “um” nas margens e contornos da diferença, desdobrando sentidos do resistir e do formar que, em sentidos distintos de alcance e significância, podemos oferecer aos processos totalizadores de condução da existência.
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Nós, da Revista Educação e Filosofia, esperamos que você, leitora e leitor, façam grande proveito da leitura!
A condição humana e a condição docente: das ilusões de onipotência ao reconhecimento do desamparo
Authors: Bogéa Diogo 
Published: March 2021

A condição humana e a condição docente: das ilusões de onipotência ao reconhecimento do desamparo
Resumo: Partindo do princípio de que todo processo educacional é aberta ou veladamente guiado por uma determinada maneira de se compreender o ser humano, procuramos nesse artigo colocar em questão os ideais de “humano”, e consequentemente, de humano-professor, que a tradição ocidental nos legou. Em seguida, tentamos indicar alguns caminhos para repensarmos contemporaneamente o que significa ser humano e, por conseguinte, o que significa ser professor. Enquanto os antigos ideais insistem em projeções de poder e invulnerabilidade ao assumir uma essência imaterial para o humano, apostamos numa concepção de humano encarnado, afetivo e desejante que envolve, em contrapartida, a disposição para assumirmos o irremediável desamparo e a incontornável vulnerabilidade que são intrínsecos à condição humana.
Palavras-chave: condição humana; ilusões de onipotência; desamparo
The human condition and the teacher condition: from the illusions of omnipotence to the recognition of helplessness
Abstract: Assuming that every educational process is openly or veiled guided by a certain way of understanding the human being, we seek in this article to question the ideals of "human," and consequently of human-teacher, that the Western tradition bequeathed to us. Next, we try to indicate some ways to rethink contemporaneously what it means to be human and, therefore, what it means to be a teacher. While the old ideals insist on projections of power and invulnerability by assuming an immaterial essence for the human, we bet on an incarnate, affective and desiring human conception that involves, on the other hand, the disposition to assume the irremediable helplessness and the unavoidable vulnerability that are intrinsic to the human condition.
Keywords: human condition; omnipotence illusions; helplessness
La condición humana y la condición docente: de las ilusiones de omnipotencia al reconocimiento del desamparo
Resumen: A partir del principio de que todo proceso educativo es abierto o veladamente guiado por una determinada manera de comprenderse el ser humano, buscamos en ese artículo plantear en cuestión los ideales de "humano", y consecuentemente, de humano-profesor, que la tradición occidental en legó. A continuación, intentamos indicar algunos caminos para repensar contemporáneamente lo que significa ser humano y, por lo tanto, lo que significa ser profesor. Mientras los antiguos ideales insisten en proyecciones de poder e invulnerabilidad al asumir una esencia inmaterial para lo humano, apostamos en una concepción de humano encarnado, afectivo y deseante que envuelve, en contrapartida, la disposición para asumir el irremediable desamparo y la ineludible vulnerabilidad que son intrínsecos a la condición humana.
Palabras clave: condición humana; ilusiones de omnipotencia; desamparo
Data de registro: 20/05/2020Data de aceite: 02/10/2020
Penerapan Pengendalian Intern pada 13 UMKM di Bandung
Authors: Wirawan Samuel , Djajadikerta Hamfri , Setiawan Amelia 
Published: March 2021

Micro, small and medium enterprises (MSMEs) as a business sector that supports the country's economy are required to have adequate internal controls to support the achievement of company goals. This research was conducted with a case study approach on culinary business. In general, the companies in this study have implemented adequate internal control components. In terms of achieving company goals, namely financial reporting, the MSMEs studied have made financial reports independently because they consider the cost factor when using expensive consultants and also most of the MSME actors already have accounting skills. However, for tax reports in general, make and reported with the help of consultants due to lack of tax regulations that often change. Regarding the achievement of operating objectives regarding the effectiveness and efficiency of operations, the MSMEs studied are still focused on production activities because production activities are the main activity to provide satisfaction to consumers by utilizing Standard Operating Procedures. Compliance with the applicable rules and laws of the 13 companies studied is varied because it depends on the presence of regulators and whether or not there are strict sanctions and involvement of related parties and bargaining power of stakeholders.Usaha mikro, kecil dan menengah (UMKM) sebagai suatu sektor usaha yang menunjang perekonomian negara dituntut untuk memiliki pengendalian intern yang memadai untuk menunjang pencapaian tujuan perusahaan. Penelitian ini dilakukan dengan melakukan pendekatan studi kasus pada UMKM yang bergerak di bidang usaha kuliner. Secara umum, perusahaan yang diteliti telah menerapkan komponen pengendalian intern yang secara memadai karena adanya keterlibatan pemilik secara langsung pada usaha tersebut. Dalam hal pencapaian tujuan perusahaan yaitu pelaporan keuangan, UMKM yang diteliti sudah membuat laporan keuangan secara mandiri karena mempertimbangkan faktor biaya jika menggunakan pihak konsultan yang mahal dan juga sebagian besar pelaku UMKM sudah memiliki kemampuan akuntansi. Namun untuk laporan pajak pada umumnya, UMKM yang diteliti membuat dan melaporkannya dengan bantuan konsultan karena mereka kurang memahami peraturan perpajakan yang seringkali berubah. Terkait pencapaian tujuan operasi tentang efektivitas dan efisiensi operasi, UMKM yang diteliti masih berfokus pada aktivitas produksi karena aktivitas produksi merupakan aktivitas utama untuk memberikan kepuasan pada konsumen dengan memanfaatkan Prosedur Operasi Baku. Kepatuhan pada aturan dan hukum yang berlaku dari 13 perusahaan yang diteliti bersifat variatif karena tergantung dari adanya pihak regulator dan juga ada atau tidaknya sanksi yang tegas serta keterlibatan pihak – pihak terkait serta daya tawar dari para pemangku kepentingan.
Diversity of aphids (Hemiptera: Aphididae) associated with potato crop in Tizi-Ouzou (North of Algeria), with new records
Authors: AIT AMAR Samia , BENOUFELLA-KITOUS Karima 
Published: March 2021

Aphids are among the phytophagous pests that cause serious damage to crop plants. In Northern Algeria, we have little information on their diversity. In this context, the study of the diversity of aphids was carried out in three regions of Tizi-Ouzou (North of Algeria) namely Tizi-Ouzou center, Tizi-Rached and Aghribs on the potato crop using yellow traps. The results showed a total richness of 65 aphid species, divided into 36 genera, 9 tribes and 8 sub-families, of which 11 species were identified for the first time in Algeria. These are Aphis coreopsidis (Thomas, 1878), Capitophorus hippophae (Walker, 1852), Cavariella theobaldi (Gillette & Bragg, 1918), Hyadaphis coriandri (B. Das, 1918), Macrosiphoniella linariae (Koch, 1855),Monelliopsis pecanis Bissell, 1983, Myzus hemerocallis Takahashi, 1921, Pseudoregma panicola (Takahashi, 1921), Rhopalosiphoninus staphyleae (Koch, 1854), Schizaphis eastopi Van Harten & Ilharco, 1971 and Ovatus inulae (Walker, 1849). The field located in the center of Tizi-Ouzou is the richest with 55 species, followed by the field of Tizi-Rached with 30 species, and 24 species have been recorded in Aghribs. During the sampling season, Hyperomyzus lactucae (Linnaeus, 1758) and Brachycaudus helichrysi (Kaltenbach, 1843) are the most abundant species with 24.44 % and 21.8 % respectively. Three aphid species have been observed on potato leaves, namely Macrosiphum euphorbiae (Thomas, 1878), Aphis gossypii Glover, 1877 and Myzus persicae (Sulzer, 1776). The latter species was observed in all three study regions.
Situation-bound utterances in Chinese as a foreign language: the effectiveness of the identification task
Authors: Conti Sergio , Lepadat Carmen 
Published: March 2021

Abstract
This paper investigates the effectiveness of the identification task on the retention of situation-bound utterances (SBUs) in Chinese as a foreign language (CFL). The participants were Italian CFL learners with different lengths of learning experience, divided into an experimental and a control group. The target SBUs were selected by means of a discourse completion questionnaire previously submitted to Italian and Chinese native speakers and Italian CFL learners. During the treatment, the experimental group was provided with six communicative functions and was asked to identify the corresponding SBUs from eight short dialogues. Subsequently, a posttest was administered to both the experimental and the control groups. Overall, the statistical analysis of the test results suggests a significant effect of the task on the participants’ ability to recall the target SBUs, both from an immediate and a longitudinal perspective. However, the data also suggest that, while the participants’ length of learning experience and minor linguistic or cultural specificities of the target formulae did not significantly influence the effectiveness of this specific vocabulary learning task, the presence vs. absence of the SBUs in either the L1 or the L2 might be a crucial factor for their successful recall.
Evolving Rasūlid Narratives of Opposition to Sultan al-Manṣūr Nūr al-Dīn ʿUmar (d. 647/1250) in Yemen
Authors: Mahoney Daniel 
Published: March 2021

Abstract
The Rasūlid chronicles of the reign of al-Manṣūr Nūr al-Dīn ʿUmar b. ʿAlī b. Rasūl depict its first ruler as steadily consolidating the political foundation of the sultanate. Most of these reports clearly portray the dominance of the sultan in Yemen during this period. But a few reveal the limitations of his power in a more complex political landscape, such as an aborted military campaign against a local tribe, an insurrection by a Zaydi sharīf, and the sultan’s assassination by his own military. These specific narratives of opposition to the sultan, however, progressively change over the course of their production from the late 13th century until the first half of the 15th century, as the strength of the sultanate initially peaks and then slowly declines. As a result, the ambiguity of al-Manṣūr ʿUmar’s authority in these narratives is largely reduced, and the historical memory of the sovereignty of the emergent Rasūlid sultanate solidifies in increasingly ideological ways.
Four Arabic Legal Documents Belonging to ʿAmmār b. Salama b. ʿAbd al-Wārith
Authors: Younes Khaled 
Published: March 2021

Abstract
This paper edits and studies four Arabic legal documents, written on two papyri, now housed in the Beinecke Rare Book and Manuscript Library at Yale University. The documents belong to a certain ʿAmmār b. Salama b. ʿAbd al-Wārith, a merchant from al-Bahnasā. Document 1 (P.CTYBR inv. 1720 verso) records a contract of sale of two inherited portions belonging to a Copt with double names, a Christian and a Muslim one. The contract touches on two significant socio-religious subjects: 1. name change after religious conversion, and 2. the loss of paternal filiation (nasab) of children born outside wedlock or in wedlock but their paternity was disavowed via the Islamic procedure of liʿān “oath of condemnation” or upon evidence of certain circumstances that prove impossibility of paternity. Documents 2.1, 2.2, and 2.3 (P.CTYBR inv. 1715 recto and verso) contains three debt acknowledgements recording payments in coin and in kind. All documents date to the year 297/909–910.
Correlation Analysis of Machine Performance Parameters and Rock Mass Properties during Tunnel Boring Machine Excavation Process: A Case Study in Yin-song Headrace Tunnel, China
Authors: Jiang Yalong , Liu Quansheng , Zhu Bitang , Pan Shaolin 
Published: March 2021

Abstract
A rock breaking process during the tunnel boring machine (TBM) excavation sequence involves a complicated interaction between the disc cutters and the tunnel face, and the excavation process is influenced both by the rock mass properties and the TBM performance. Hence, in achieving a highly efficient TBM excavation, a mutual feedback analysis of rock mass properties and machine parameters is important. In this study, a correlation analysis of rock mass properties and TBM parameters is conducted based on the field data obtained from the Yin-song headrace tunnel in Jilin Province, China. Firstly, the correlation between the rock mass properties (i.e., uniaxial compression strength and rock quality designation index) and the machine parameters (i.e., thrust force, cutterhead torque, rotational speed, penetration depth, and penetration rate) obtained during the stable operation stage of TBM is extensively investigated. The variation in the TBM penetration rate as a function of rock mass properties and machine operation parameters is studied. A statistical prediction model that defines the effects of rock mass properties on the TBM penetration rate is established by multivariate linear regression analysis. The validity of the prediction model is verified by using the in situ monitoring data obtained from two different chainages of the project. This study can help rationalize the TBM machine parameters in order to obtain a highly efficient TBM excavation and a low life-cycle cost for the machine.
Monitoring energy audit for energy savings using non cost technique at electronics company
Authors: Yusoff Ahmad Razlan , Mohd Foudzi M.N. , Taib M.Y. , Arnizam Shah A.S. 
Published: March 2021

Energy is essential element for economical growth in industry and it measures directly the standard of living for a country. The economical growth and energy demand in the modern society need to be reduced the energy consumption. In this paper, energy consumption was monitored and audited for an electronic company in Malaysia. The energy consumption was analysed based on electrical bill and then the power consumption has been verified based on energy audit process using power analyser for this electronic company. It is monitored that the energy audit for the whole company and point out the possiblity of non cost energy saving technique. From 10 locations analyses, 3 locations are main soursces contribite to high energy consumption. There are compressor room, busbar 15 and busbar 16 relates to chiller room that supply the air conditioning system in the company. The energy audit can provide the non cost suitable technique for energy savings and profit improvement in this electronic company.
Herding the Crowd: Using Automated Planning for Better Crowdsourced Planning
Authors: Manikonda Lydia , Chakraborti Tathagata , Talamadupula Kartik , Kambhampati Subbarao 
Published: March 2021

One subclass of human computation applications are those directed at tasks that involve planning (e.g. tour planning) and scheduling (e.g. conference scheduling). Interestingly, work on these systems shows that even primitive forms of automated oversight on the human contributors helps in significantly improving the effectiveness of the humans/crowd. In this paper, we argue that the automated oversight used in these systems can be viewed as a primitive automated planner, and that there are several opportunities for more sophisticated automated planning in effectively steering crowdsourced planning. Straightforward adaptation of current planning technology is however hampered by the mismatch between the capabilities of human workers and automated planners. We identify and partially address two important challenges that need to be overcome before such adaptation of planning technology can occur: (i) interpreting inputs of the human workers (and the requester) and (ii) steering or critiquing plans produced by the human workers, armed only with incomplete domain and preference models. To these ends, we describe the implementation of AI-MIX, a tour plan generation system that uses automated checks and alerts to improve the quality of plans created by human workers.
Topical Video Search: Analysing Video Concept Annotation through Crowdsourcing Games
Authors: Gligorov Riste , Hildebrand Michiel , Van Ossenbruggen Jacco , Aroyo Lora , Schreiber Guus 
Published: March 2021

Games with a purpose (GWAPs) are increasingly used in audio-visual collections as a mechanism for annotating videos through tagging. One such GWAP is Waisda?, a video labeling game where players tag streaming video and win points by reaching consensus on tags with other players. The open-ended and unconstrained manner of tagging in the fast-paced setting of the game has fundamental impact on the resulting tags. We find that Waisda? tags predominately describe visual objects and rarely refer to the topics of the videos. In this study we evaluate to what extent the tags entered by players can be regarded as topical descriptors of the video material. Moreover, we characterize the quality of the user tags as topical descriptors with the aim to detect and filter out the bad ones. Our results show that after filtering, game tags perform equally well compared to the manually crafted metadata when it comes to accessing the videos based on topic. An important consequence of this finding is that tagging games can provide a cost-effective alternative in situations when manual annotation by professionals is too costly.
MetaCrowd: Crowdsourcing Biomedical Metadata Quality Assessment
Authors: Zaveri Amrapali , Hu Wei , Dumontier Michel 
Published: March 2021

To reuse the enormous amounts of biomedical data available on the Web, there is an urgent need for good quality metadata. This is extremely important to ensure that data is maximally Findable, Accessible, Interoperable and Reusable. The Gene Expression Omnibus (GEO) allow users to specify metadata in the form of textual key: value pairs (e.g. sex: female). However, since there is no structured vocabulary or format available, the 44,000,000+ key: value pairs suffer from numerous quality issues. Using domain experts for the curation is not only time consuming but also unscalable. Thus, in our approach, MetaCrowd, we apply crowdsourcing as a means for GEO metadata quality assessment. Our results show crowdsourcing is a reliable and feasible way to identify similar as well as erroneous metadata in GEO. This is extremely useful for data consumers and producers for curating and providing good quality metadata.
Bones of Contention: Reflections on Osteoarchaeology and the Baltic Region
Authors: Bartosiewicz László 
Published: March 2021

During the last decade, some of the most significant archaeological interpretations included the integrated use of scientific methods, including osteoarchaeology. The identification, analysis and interpretation of human and animal remains from archaeological sites has been developing along increasingly different trajectories, due to the different aspects of daily life the bones of animals and humans illustrate. This paper is a review of the position osteoarchaeological research has achieved since the 1960s, through the example of its beginnings in the mid-20th century in Sweden. Similarities and differences between the histories, contents of and directions in human and animal osteoarchaeology are reviewed, revealing some controversies in the ways the results of the discipline have been embraced by the broader archaeological community. Similarly to archaeological research, increasingly complex analytical methods help refining results obtained by traditional morphometric methods applied to bones. This trend will continue in the foreseeable future: scientific methods will keep on contributing to valuable insights into past societies. Special sections in the paper are devoted to the possibilities of disseminating the results of osteoarchaeology through formal and informal networks such as publications, teaching and conferences within the context of the Baltic region through the example of archaeozoological research.