bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sindrome de Behçet: Enfermedad de la ruta de la seda
Authors: Clavijo Tinoco Fair , Herrera Alvarado Alcides , Herrera Villalba Harol , Fernández Franco Jorge , Diaz Alcendra Oscar , Varela Lourdes , Silva Olivia 
Published: November 2021

La enfermedad de Behcet es un trastorno inflamatorio multisistémico vasculítico de vaso variable caracterizado por úlceras aftosas orales, genitales, recurrentes, panuveítis bilateral posterior, manifestaciones articulares y ocasionalmente compromiso del sistema nervioso central y grandes vasos . Las variadas manifestaciones clínicas y la falta de pruebas patognomónicas hacen de la enfermedad un reto diagnóstico cuya prevalencia en Colombia se desconoce. El diagnostico se basa en criterios diagnósticos propuestos ante la falta de una prueba Gold Standard. Con relación a la etiología se han estudiado diversas teorías, entre ellas las de origen inmunológico, especialmente por la existencia del HLA - B51, le siguen aquellas que responsabilizan a agentes infecciosos, daño endotelial, entre otros. Se presenta el caso de un paciente femenino de 35 años, con cuadro crónico y recurrente de aftas orales, presencia de lesiones dermatológicas y aparición de ulceras genitales. Descartándose causas inmunomediadas, infecciosas e inflamatorias. Considerándose un cuadro de aftosis bipolar recurrente y ante los síntomas dermatológicos, se propuso aplicar los criterios diagnósticos del International Team for the Revision of International Criteria for Behçet Disease, con una puntuación de 4, lo que avala el diagnostico de enfermedad de Behcet. El manejo se basó en la instauración de medidas terapéuticas a base de corticosteroides sistémicos e inmunosupresores, con adecuada respuesta clínica.
Dampak Kerusakan Lingkungan Akibat Penambangan Pasir Merapi di Klaten
Authors: Syaifulloh Arief K. 
Published: November 2021

Penelitian yuridis empiris ini dilakukan untuk mengkaji dampak kerusakan lingkungan akibat penambangan pasir Merapi di Klaten. Amanah konstitusi menegaskan bahwa bumi, air, dan kekayaan alam yang terkandung di dalamnya dikuasai oleh negara dan dipergunakan untuk sebesar-besar kemakmuran rakyat. Hasil penelitian diperoleh bahwa penambangan pasir merapi di Klaten Jawa Tengah memiliki beberapa dampak. Pertama, penambangan berdampak pada rusaknya lahan pertanian dan lahan perkebunan. Rusaknya lahan ini mengancam ketersediaan lahan bagi generasi petani yang akan datang dan tentu akan berpengaruh pada ketersediaan pangan. Dampak kedua yang diakibatkan penambangan yaitu merusak jalur evakuasi dan yang ketiga yaitu mengganggu resapan air, ekologi, serta rawan longsor.
Does female genital mutilation/cutting have any effect on normal birth?
Authors: Tamburaci Esra , Birge Özer 
Published: November 2021

Background: World Health Organization’s (WHO) defines female genital mutilation (FGM) as all procedures involving the total or partial removal of female external genitalia without any medical reasons. It is estimated that about 100 million women worldwide are circumcised. After circumcision compications such as bleeding, infection, shock, menstrual irregularity, dysuria, frequent urinary tract infections, pelvic pain and difficulty in sexual intercourse occur with varying frequencies.Methods: In this article, we aimed to discuss normal vaginal delivery results of 45 term pregnant cases with 3 types of female genital multilation/circumcision. We know that the vaginal entrance is closed as a result of adhesions in the genital area due to circumcision and secondary complications may develop.Results: The mean age of 45 patients included in the study was 26.2±8.78 years. Considering the postpartum complications, bilateral labial tissue ruptures in 15 cases, followed by vaginal hematoma in 9 cases, anal sphincter damage in 11 cases, deep episiotomy tears in 8 cases, periurethral tears in 8 cases, deep cervical tears in 8 cases, vulvar epidermoid cyst ruptures in 4 cases and 4 cases. perineal body ruptures were seen in 4 cases, vulvar hematoma in 4 cases, and vaginal mucosal damage in 9 cases.Conclusions: It has been shown once again that FGM/C is a method that completely changes the female vaginal anatomy and has very serious delivery complications. It is obvious that serious educations and studies need to be done in the countries where this method is applied.
Checklist approach to vertigo: audit of current practice in a tertiary referral center
Authors: Venkataramani Nithya , Sachidananda Ravi , Nagarajaiah Rajesh Karalumangala 
Published: November 2021

<p class="abstract"><strong>Background:</strong> Vertigo is a complex symptom which can be present in multiple conditions, some of which are life threatening. Diagnosing a patient with vertigo could sometimes be challenging and there is a need for a comprehensive, yet easily reproducible diagnostic model with emphasis on the red flag signs. A simple way to achieve this is a checklist. The aim of the study was to propose a diagnostic checklist for patients presenting with vertigo to an ENT clinic to aid diagnosis and prevent diagnostic errors.</p><p class="abstract"><strong>Methods:</strong> A diagnostic checklist was used in all patients who presented with the symptom of vertigo, necessary tests were conducted and referrals were done when required. </p><p class="abstract"><strong>Results:</strong> Out of eighty-five patients who presented with symptom of dizziness to ENT clinic, all patients received a definitive diagnosis treatment plan with the help of checklist.</p><p class="abstract"><strong>Conclusions:</strong> Checklist is an effective way to ensure elaborate assessment of the patient with emphasis on the red flag signs. It is a very important tool to arrive at diagnosis and formulate treatment plan.</p>
Impact of COVID-19 on obstetric care delivery and maternal and perinatal outcome
Authors: Thomas Susan , Kattukaran Anoj , Menon Prameela 
Published: November 2021

Corona virus disease 2019 (COVID-19) has changed all our lives in a significant way. Despite the fact that pregnant women were placed in the ‘vulnerable group’, antenatal care services have been affected by the pandemic. We are conducting the study to find the impact of COVID-19 on antenatal care and its impact on maternal and perinatal outcomes and thereby giving us an insight on how to improve our provision of care.1. To find the effect of COVID-19 on obstetric care delivery in non-covid and covid patients. 2. To assess the maternal and perinatal outcome in Covid positive patients.This is a descriptive study conducted at Amala Institute of Medical Sciences, Thrissur, Kerala during the period of April 2020 to December 2020. All pregnant women who delivered here during the period were taken in the study. Data was collected through pre prepared questionnaire by direct or telephonic conversation.Total deliveries were 919 with response rate of 85.6%. During pandemic, approximately 54% of women missed their ANC visit due to fear of Covid. Absence of partner during visits, delivery and postnatal period was a cause for nervousness for 56.40% of mothers. Telemedicine was used by 52% of subjects and was found effective.Antenatal care is essential but challenging during COVID-19 pandemic. A protocol based approach is needed which is cost-effective and easy.
Compare safety and efficacy of intramuscular progesterone versus vaginal progesterone in prevention of preterm labour
Authors: Chaudhari Shilpa , Mishra Aparajita , Hol Kishor , Shastri Shraddha 
Published: November 2021

Currently preterm labour is one of the most challenging problem faced by both obstetricians and perinatologists, this episode in the course of woman’s pregnancy takes a heavy tool for perinatal mortality which accounts for approximately 50-75%. The incidence of preterm labour is estimated to be 5-10% of all pregnancies. It was a prospective randomize control study. All the cases with inclusion and exclusion criteria were selected during the study period. The subjects were randomized into two groups with group A received vaginal micronized progesteron and group B intramuscular 17a hydroxyprogesteron caproate. Total of 100 cases were included in this study. All preterm pregnancy of more than 20 weeks were considered in this study. Initial nefidipine 10 mg, 4 tablets 15 min apart was given for tocolytic activity for 48 hours. Injection bethamethasone 12 mg I.M 2 doses in a duration of 24 hours apart is given for fetal lung maturity. One group will receive weekly intramuscular 17a hydroxyprogesteron (250 mg) injection while other group will receive daily micronized vaginal progesteron suppository (200mg). Subsequently compare the safety and efficacy of intramuscular progesterone versus micronized progesterone as a maintenance therapy in preventing preterm labour and analyse maternal and fetal factors.Subsequently compared the safety and efficacy of intramuscular progesterone versus micronized progesterone as a maintenance therapy in preventing preterm labour.This analysis showed that women who randomized to progesterone prophylaxis had a significantly increase in duration of pregnancy. The mean ± SD of birthweight in Group A and Group B was 2784.2 ± 490.7 gm and 2813.9 ± 363.3 gm respectively which confirmed the positive effects of progesterone on increasing infants’ weights at birth. Authors concluded that progesterone therapy had acceptable efficacy in the prevention of preterm labor in terms of prolongation of delivery and by increasing gestational age at delivery.
Uterine rupture at the fundus during labor: A case report
Authors: Yadav Sunita , Chaudhary Susheela , Malhotra Vani 
Published: November 2021

Uterine rupture is a rare but catastrophic complication seen in obstetrical practice. The most crucial predisposing factor is previous caesarean scar and it is generally being reported during labor in patients with scarred uterus. Although rare, rupture of an unscarred uterus is one of the most terrible obstetric complications, resulting in maternal and fetal jeopardy. Shoulder dystocia is one of the most difficult complications of labour that is unpredictable and therefore unpreventable. In neglected cases, grave maternal complications like obstructed labour and rupture of uterus can occur. Very rarely, the reverse, uterine rupture leading to shoulder dystocia can also occur. The present case is reported to emphasize the importance of early recognition of this condition. A 32 year old gravida 5 para 2 live 2 abortion 2 with 9 month period of gestation presented to labor room with shoulder dystocia, with history of fundal pressure. After delivery of head, pain subsided and the trunk failed to deliver. Her previous two deliveries were by normal vaginal delivery 8 years and 5 years back respectively. She had previous two abortions 6 years and 3 years back respectively. Both were spontaneous expulsion followed by dilatation and curettage. On examination, clinical diagnosis of rupture uterus was made and patient was taken up for laparotomy. On laparotomy, fetal body and limbs along with the placenta was seen lying in the abdominal cavity and head was in uterus. Baby of 2.34 kg was extracted as breech. A linear rupture of around 10-12 centimeter was present at fundo-posterior region. Uterus was repaired in 3 layers and bilateral tubal ligation was done. Patient was discharged on post- operative day 10 without any complications.In women with high risk for uterine rupture, delivery must be conducted at tertiary hospitals where facilities for emergency caesarean is available. In these patients, if shoulder dystocia occurs, rupture of the uterus must be suspected as an underlying cause. Assisted fundal pressure during delivery can result in trauma even to the unscarred uterus and cause traumatic uterine rupture. Early diagnosis is vital if maternal morbidity is to be reduced.
Histopathological spectrum of nonneoplastic lesions of large intestine- A three year study
Authors: Anvikar Arti Rameshrao , Salunke Leena Shrikant , Gosavi Alka Vikas , Palve Priyanka Santosh 
Published: November 2021

Large intestine is a site for an array of different nonneoplastic and neoplastic lesions. Clinical manifestations may overlap, thus making the diagnosis difficult and creating the need for tissue diagnosis. Our study aims at detail histopathological examination of the different non neoplastic lesions of large intestine. A total of 30 nonneoplastic lesions of large intestine were studied over a period of 3 years. Both resected specimens and endoscopic biopsy specimens were included. Histopathological findings were studied along with analysis of the distribution of lesions and correlation of the histopathological findings with clinical parameters. The lesions were distributed in all age groups, with maximum frequency in 5 to 8 decades. The frequency was significantly higher in males (23 cases- 76.7%) as compared to females (7 cases- 23.3%). The most common lesion was perforation (10 cases), followed by gangrene (4 cases). Two cases had gangrene with perforation. Other lesions included Hirschprung’s disease (5 cases), Crohn’s disease (two cases) and one case each of Enteric duplication cyst, tuberculosis, amoebic colitis with perforation and Peutz-Jeghers polyp. Three cases had nonspecific inflammation. Our study emphasizes the importance of histopathological examination in the management of colonic lesions
Spectrum of soft tissue lesions in upper and lower extremities on fine needle aspiration cytology: A three years’ experience from Western Indian population
Authors: Sisodiya Sneha , Gaikwad Vaishali P , Naik Leena 
Published: November 2021

Soft tissue lesions have a wide spectrum which includes non- neoplastic, benign & malignant lesions. FNAC act as preliminary diagnostic tool providing a predictive diagnosis of a benign or malignant soft tissue neoplasm and thus helps for further intervention. This study discusses the spectrum of FNAC of soft tissue lesions in upper and lower limbs.All cytology smears of soft tissue lesions from both upper and lower limbs were included over a period of three years at tertiary care hospital. The most common age group was 31 to 40 years with male to female ratio being 1.3:1. The spectrum included broadly neoplastic (65.7%) & non-neoplastic (34.3%) cases. The neoplasms were further divided as benign (42.8 %), malignant (18.6%) and suspicious for neoplasm (4.3%) whereas (34.3 %) were non-neoplastic lesions. The most common lesion was giant cell tumor (GCT) of tendon sheath. The most common site was hand (24%) followed by feet (22.5%). FNAC of soft tissue lesions is useful for differentiating various lesions and neoplasms in extremities so as to help patients in further management.
Undifferentiated carcinoma with osteoclastic giant cells of pancreas: Case report and brief literature review
Authors: Dekate Jyoti Parag , Kelkeri Manjula V , Garudadri Gowri 
Published: November 2021

Undifferentiated carcinoma with osteoclastic giant cells is a distinctive rare neoplasm involving pancreas and rarely bile ducts. This neoplasm shows characteristic histologic features with variable admixture of mononuclear histiocytic cells, non- neoplastic osteoclastic giant cells and neoplastic mononuclear cell component. Though, this tumor has been shown to share genetic alterations with pancreatic ductal adenocarcinoma, clinically, it behaves unpredictably with a substantial proportion of patient showing prolonged survival period. We present a case of this rare pancreatic tumour with brief literature review discussing the key pathologic features, immunophenotype, genetic profile and clinical behavior. Undifferentiated carcinoma with osteoclastic giant cells is a rare neoplasm in pancreas which is believed to be of epithelial origin and shares genetic aberrations with ductal adenocarcinoma. Despite this, these tumours have better prognosis with prolonged survival period.
Ekstraksi Minyak Atsiri dari Bunga Mawar (Rosa hybrda L.) dengan Metode Solvent Free Microwave Extraction
Authors: Yuniati Yuyun , Putri Saras Nurani , Sambawa Pradipta Risang Ratna , Bhuana Donny Satria , Mahfud Mahfud 
Published: November 2021

To date, essential oils still play an important role in various aspects of human life. Flowers are essential oil-producing plants that still need to be further explored, of which rose petals (Rosa hybrda L.) are an option for types of flowers that have the potential to produce economical essential oils. In this study, solvent-free microwave extraction (SFME) was used as an essential oil extraction method, which is considered safe because it does not use heat energy and chemical solvents which can be considered to trigger a decrease in the quality of the oil extract. The optimum microwave power in this study is 560 Watt with a yield of 0.0124%. The difference in the value of the feed intake ratio to the volume of the distiller (F/D) influences yield, where the F/D value of 0.15 g/mL gives the highest yield value of 0.0145%. The result of the Gas Chromatography Mass Spectrometry (GCMS) analysis shows rose flower essential oil extract provided a profile of 12 compounds, of which three dominant compounds are β-phenylethyl acetate, 2-isopropyl-5-methyl-9-methylene-bicyclo-1-decene, and nonadecane. Keywords: Extraction, rose flower petals, solvent-free microwave extraction (SFME), essential oils Hingga saat ini, minyak atsiri masih memegang peranan penting untuk berbagai aspek kehidupan manusia. Bunga-bungaan merupakan tanaman penghasil minyak atsiri yang masih perlu dieksplorasi lebih lanjut, yang mana mahkota bunga mawar (Rosa hybrda L.) adalah satu opsi jenis bunga yang berpotensi sebagai penghasil minyak atsiri bernilai ekonomis. Pada penelitian ini digunakan solvent-free microwave extraction (SFME) sebagai metode ekstraksi minyak atsiri yang dinilai aman karena tidak menggunakan energi panas dan bahan pelarut kimia yang dapat dianggap memicu penurunan kualitas ekstrak minyak. Daya microwave optimum pada penelitian ini adalah 560 Watt dengan perolehan yield sebesar 0,0124%. Perbedaan nilai rasio feed masuk terhadap volume distiler (F/D) memberikan pengaruh terhadap hasil rendemen, yang mana nilai F/D 0,15 g/mL memberikan nilai rendemen tertinggi sebesar 0,0145%. Hasil analisis Gas Chromatography Mass Spectrometry (GCMS) menunjukkan bahwa ekstrak minyak atsiri bunga mawar memberikan profil 12 senyawa dengan tiga senyawa dominan yaitu β-phenylethyl acetate, 2-isopropyl-5-methyl-9-methylene-bicyclo-1-decene, dan nonadecane. Kata kunci: Ekstraksi, mahkota bunga mawar, solvent-free microwave extraction
Analysis of Oscillating Fishing Tool Efficiency for Stuck Assembly Recovery in Field X
Authors: Bayuartha Pratama Wangsit , Sitorus Parluhutan Alvin , Sinaga Rahmat , Sugiarto Tomi , Tokoh Kristoforus Widyas , Muryanto Bonifasius , Manalu Dasa , Faksilanto Dyan , Hendarno Boby , Ardiansyah Taufiq 
Published: November 2021

Abstract
As conventional fishing assembly offers a degree of recovery chance, such chance can be increased by utilizing an Oscillating Fishing Tool (OFT). The OFT is a fishing Bottom Hole Assembly (BHA) component that delivers low-magnitude; high-frequency oscillation. The continuous motion that the tool provides complements the impact generated by the fishing jar. This paper reviews the successful case history in Field X, which was in fact the first utilization of OFT for a fishing application in the field.
Method of analysis involve comparing fishing sequence without and with the OFT. The OFT was used in Offshore Field X to recover a mechanically stuck 550-meter long Tubing Conveyed Perforating Gun assembly inside 9 5/8" casing that could potentially lead to loss of access into the 6 oil reserves candidate perforation zones. Initially the assembly had been stuck for two days, during which conventional fishing BHA was used to retrieve it to no avail, even after jarring for most of that time. OFT was then incorporated in the final fishing BHA and operated in combination with jarring operation.
After around twelve hours of oscillating and jarring, the fish was able to be released from the initial stuck point. When tripping the string out, however, the assembly was stuck at high dog-leg severity area near the surface. At that point, in combination with applying substantial overpull, OFT was utilized further to recover the entire string. Upon fish retrieval, it was evident that post detonation, the TCP gun had swelled into 8.6 inches in diameter. In summary, oscillating and jarring for thirty-six cumulative hours successfully released the swelled TCP gun assembly from the stuck occurrences. In conclusion, the operation showed that the OFT serves as a higher level of fishing tool option that offers a particular excitation mode to the stuck assembly.
Stuck assembly in a cased hole presents potential loss of oil reserves. Particularly in offshore application, the situation can also be costly. With reduced chance of recovery as time passes by, operation is hindered from being able to proceed to the next completion phase. The case proved OFT to have played an important role in improving fishing probability of success and should be considered as standard fishing BHA in the future.
Integrity Evaluation and Management in High Temperature High Pressure and High Production Rate Wells in Southwest China
Authors: Zhu Dajiang , Fan Yu , Zhang Huali , Li Yufei , Zhang Lin , Wang Chuanlei , Wang Xiaolei , Chen Hao , Lu Linfeng , Duan Yunqi 
Published: November 2021

Abstract
The Longwangmiao (referred to as LM) gas field in southwest China has characteristics of high temperature (144~156 °C), high pressure(75~76 MPa), and high production rate (70~100×104 m3/d). Serious well integrity problems were encountered in the development process; 21% of 56 wells were subjected to sustained casing pressure (SCP)(≥20 MPa). Downhole leak detection logs indicated the main cause was tubing connection leakage at a depth range of 0~2400 m. Wellhead growth was present in 33 wells and 4 wells exhibited gas leakage through wellhead valves.
Theoretical analysis and field tests were conducted to investigate and manage well integrity problems. A method to calculate the allowable pressure for different annuli was proposed based on string strength analysis, and downhole leak detection was conducted using ultrasonic leak detection method. A multi-string mechanical model to predict wellhead growth was established and the threshold values were calculated under different gas rates. According to the structure of wellhead, a method based on ultrasonic phased array to detect the work state of the wellhead was adopted, which measured the actual thickness of key valves to evaluate service life. For wells with SCP, the allowable pressure for different annuli was calculated and the pressure management charts were drawn and all wells were in steady production. Downhole leak detection showed that SCP in the A annulus (annulus between the tubing and production casing) was caused by connection leakage of tubing. In newly completed wells, a premium connection was adopted based on tests under cyclic structural and environmental thermal loads that the connections may encounter at various production phases, and the total ratio of SCP in newly completed wells decreased by 31.4%. Wellhead growth was predicted and compared with actual data, which showed an increase in average accuracy of 20~30% compared to the results from the WellCAT software. Sensitivity analysis revealed that the length of un-cemented casing and the production rate were the critical factors affecting the wellhead growth. The valve leakage of FF level material wellhead was caused due to corrosion after the removal of the coating, and no leakage was detected in the HH level material wellhead. Thickness survey showed that the average reduction was 0.085 mm~0.23 mm for HH wellhead, and 1.12 mm~2.24 mm for FF wellhead.