bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy Evaluation Study for Microburst Insulin Infusion: A Novel Model of Care
Authors: Howard Steven W. , Zhang Zidong , Linomaz Jacob , Lam Wing , Qian Zhengmin , Thurman Jerry , BeLue Rhonda 
Published: August 2021

Objectives: This study aims to evaluate the impact of Microburst Insulin Infusion (MII) treatment on Type 1 and 2 diabetic patients' HbA1c, lipids, peripheral neuropathy, and patient-reported health status.Methods: We reviewed clinical charts, including lab results, for more than 80 diabetic and pre-diabetic patients treated at one U.S. outpatient clinic in St. Louis, Missouri between February 2017 and December 2019. Data included patient demographics, treatment data, lab and neuropathy tests, and self-reported patient health status questions.The explanatory variable was number of months of MII treatment. Treatments are 3–4 h in length, with two intensive infusions the first week and one treatment each week thereafter, usually for 12 weeks total. Lab tests were at 12-week intervals.Generalized linear modeling and t-tests assessed the significance of differences between patients' baseline lab values, neuropathy measures, and health status before treatment vs. after final treatment.Results: Number of MII treatments per patient ranged from 1 to 262, over 1–24 months. Time in MII treatment was significantly associated with reductions in HbA1c by nearly 0.04 points per month, and triglycerides declined 3 points per month. Neuropathy measures of large toe vibratory sensation (clanging tuning fork) improved significantly, as did patient-reported health and feelings of improvement since beginning treatment.Discussion: The MII therapy appears to be efficacious in treating diabetic patients, particularly those with complications like neuropathy. Our findings affirmed several other studies. We uniquely incorporated patient health questionnaires, and empirically studied MII treatment efficacy for diabetes in a population large enough to permit statistically valid inferences. With multiple waves of data for over 80 patients, this is one of the most extensive quantitative studies of microburst insulin infusion therapy conducted to date, with protocols more uniformly implemented and survey instruments more consistently administered by the same clinical team. Given the advances in insulin infusion therapy brought by MII, and early indications of its efficacy, the time is right for more in-depth studies of the outcomes patients can achieve, the physiological mechanisms by which they occur, MII's comparative effectiveness vis-à-vis traditional treatments, and cost-effectiveness.
Hyperuricemia, Elevated Body Mass Index, Female Sex, and Albuminuria Increase the Probability of Elevated High-Sensitivity C-Reactive Protein: Results From the National Health and Nutrition Examination Survey 2015–2018
Authors: Kaspar Cristin D. W. , Lu Juan 
Published: August 2021

Importance: High uric acid (UA) is hypothesized to worsen kidney and cardiovascular disease morbidity via activation of systemic inflammation. Clinical trials of UA modification report reduction of the inflammatory marker high sensitivity C-reactive protein (hs-CRP) as an outcome measure, but studies have not demonstrated that hyperuricemia independently increases hs-CRP when adjusted for important confounders such as body mass index (BMI), sex, and age.Objective: To identify clinical risk factors for elevated hs-CRP, including but not limited to hyperuricemia, through a cross-sectional analysis of the National Health and Nutrition Examination Survey (NHANES) 2015–2018.Results: In the final multivariate logistic regression model, the exposure with the strongest effect on the odds of elevated hs-CRP was BMI in the fourth quartile, OR = 13.1 (95% CI 6.25–27.42), followed by female sex (OR = 4.9, 95% CI 2.92–8.34), hyperuricemia (OR = 2.2, 95% CI 1.36–3.45), urine albumin creatinine ratio (ACR; OR = 1.5, 95% CI 1.09–2.18), poor overall health (OR = 1.4, 95% CI 1.18–1.58), and interactions between hyperuricemia and sex (OR = 1.4, 95% CI 1.05–1.83), and between BMI and sex (OR = 1.2, 95% CI 1.03–1.47). Notably, chronic kidney disease (CKD) and CKD surrogates were not associated with hs-CRP despite urine ACR maintaining a significant independent effect.Conclusions: In this national population-based study, we demonstrated that hyperuricemia significantly increases the odds of elevated hs-CRP, independent from BMI, female sex, urine ACR, and overall health status. Further study is recommended to better understand the sex difference in this association and the role of albuminuria, but not CKD, in systemic inflammation.
COMBINING BOOTSTRAPPING AND GENETIC ALGORITHM BASED ON FEATURE SELECTION FOR FRANCHISE LOCATION PROSPECTS PREDICTION
Authors: Mardiana Tati 
Published: August 2021

Location selection is crucial in the franchise fast-food industry. A thorough location selection model paired with a proper analytical technique can considerably improve the performance of placement decisions, attract more customers, and raise market share and profitability. Franchise location data sets have an imbalanced class nature. The franchise location prospect prediction performance decreased as a result of the dataset's noisy characteristics. We developed a hybrid approach to improve franchise location prospect prediction performance in this study. It combines Bootstrapping to address class imbalance problems and Genetic Algorithm (GA) to select relevant features in the franchise location prospect prediction. We experimented with four different classification methods (Naive Bayes, C4.5, Random Forest, ID3, Gradient Boosted Trees). The results show that almost all classifiers that use Bootstrapping and GA outperform the original technique. We employ the Confusion Matrix and Root Mean Squared Error (RMSE) to examine the proposed method's performance. The test results demonstrate that the proposed method considerably enhances the franchise location prospect's classification performance.
The Access to and Use of ICT in Learning English: A Case of University Students
Authors: Adeliani Cici , Harahap Alamsyah , Sofyan Dedi , Kurniawan Ildi , Lubis Azhar Aziz 
Published: August 2021

This research aimed to find out the students’ access to ICT application and how far ICT application helps students in mastering English language skills faced by English students of English Education Study Program at the University of Bengkulu in the 2020/2021 academic year. This research was an explanatory sequential mixed methods design. The population of this research was English students of English Education Study Program at the University of Bengkulu. The sample of this research was selected by using purposive sampling technique, totaling 80 students for questionnaire and 24 students for interview. The data were collected by using questionnaire and interview. The instruments were consisted of 15 items adapted from Dang Hoang Tri and Nhung Hong Thi Nguyen (2014). This research used Microsoft Excel to analyze the data. The result of this study showed that students access 15 ICT applications in English learning. Also, researcher found that the majority of students have positive perception towards ICT application can help students in mastering English language skills.
OPINI GURU TENTANG PEMANFAATAN GOOGLE CLASSROOM DI ERA NEW NORMAL PANDEMI COVID-19
Authors: EFLINA  
Published: August 2021

ABSTRAK
Penelitian ini bertujuan untuk memberi gambaran opini guru tentang pemanfaatan google classroom sebagai media pembelajaran di era new normal pandemi covid-19. Guru berperan sangat penting untuk tercapainya pendidikan yang berkualitas dan berkarakter. Metode pembelajaran yang disampaikan sebaiknya disajikan secara menarik dan mudah dipahami oleh siswa.Karenanya pemilihan media pembelajaran yang tepat pada situasi darurat, perlu menjadi bahan pertimbangan para guru selaku pemeran utama dalam dunia pendidikan. Penelitian dilakukan dengan metode survey terhadap 31 orang guru yang mengajar di SMAN 1 Bakam dan SMAN 1 Pemali melalui sebaran angket tertutup dan terbuka dalam bentuk google form. Hasil angket disajikan dalam bentuk tabel dan grafik, serta dianalisis secara deskriptif. Terdapat rata-rata 88,7 % guru memberi respon positif dan menyatakan setuju pada keunggulan fitur-fitur google classroom. Hal ini didukung pula dari hasil angket terbuka yang menyatakan bahwa keunggulan google classroom tersebut, memfasilitasi semua kebutuhan guru, mulai dari mengontrol kehadiran siswa, membuat kelas, menyampaikan materi dan penugasan, melakukan evaluasi dan penilaian, serta memberi umpan balik terhadap pekerjaan siswa. Semua data hasil pekerjan siswa, tersimpan dan terorganisir dengan baik pada google dan berlangsung lama.
Kata kunci: opini guru; google classroom; pandemi covid-19

ABSTARCT
This study aims to provide an overview of the teacher's opinion about the use of google classroom as a learning medium in the new normal era of the Covid-19 pandemic. Teachers play a very important role in achieving quality and character education. The learning method that is delivered should be presented in an attractive manner and easily understood by students. Therefore, choosing the right learning media in an emergency situation needs to be taken into consideration by teachers as the main players in the world of education. The research was conducted by surveying 31 teachers who taught at SMAN 1 Bakam and SMAN 1 Pemali through closed and open questionnaires in the form of google form. The results of the questionnaire were presented in tables and graphs, and were analyzed descriptively. There was an average of 88.7% of teachers giving positive responses and agreeing on the advantages of the Google classroom features. This is also supported by the results of an open questionnaire which states that the advantages of the google classroom are facilitating all teacher needs, starting from controlling student attendance, creating classes, delivering materials and assignments, conducting evaluations and assessments, and providing feedback on student work. All data on student work is stored and well organized on Google and lasts a long time.
Key words: teachers opinion; google classroom; the covid-19 pandemic
"قواعد النيات والمقاصد عند الحافظ العراقي وابنه الحافظ أبي زرعة من خلال كتابهما "طرح التثريب
Authors: Muhammad Ikhsan  , Hassani Mohammed Nour  
Published: August 2021

This study aims to explore the principles of the Islamic law that govern the intentions and intentions of the mukallaf in the views of al-Hafizh al-Iraqi and his son, al-Hafizh Abu Zur'ah, in their work, Tharh al-Tatsrib. This research seeks to raise the position of al-Hafizh al-Iraqi and his son, al-Hafizh Abu Zur'ah, in the study of Islamic law, through a study of fiqh principles relating to the intention of mukallaf and their application in Islamic law. The method used in this research is the inductive method and legal analysis. Among the important conclusions of this research is that there are at least 10 rules related to intention in the Book of Tharh al-Tatsrib, all of which are then explained the arguments and applications of Islamic law. This research also found the superiority of al-Hafizh al-Iraqy and his son, al-Hafizh Abu Zur'ah, in the study of Islamic law, although both were more popular in the study of hadith; which is shown by their interaction with the rules of Islamic law in their work, Tharh al-Tatsrib.
الفروق الفقهية في كتب فروع المذهب الشافعي
Authors: Akhmad Hanafi Dain Yunta  , Awal Rifai Wahab  
Published: August 2021

Some fuqaha of syafiiyah in describing problems that have the same form but different laws which later became known as furuq fiqhiyyah, fuqaha of syafiiyah has been very prominent in describing furuq fiqhiyyah in the books of furu' mazhab. After reading some of the problems of furuq fiqhiyyah in some of these furu' books, the author finds that there is a difference between one writer and another in describing this furuq fiqhiyyah. Therefore, we need an initial article that explains the general guidelines about furuq fiqhiyyah. The author in this study uses the inductive deductive method by doing a general reading of several books of furu schools of syafiyyah, then concludes the method of describing their furuq fiqhiyyah. The conclusion that the authors get is that fuqaha of syafiiyah in describing furuq fiqhiyyah in the furu' mazhab book uses several categories: first: based on the mention of lafadz furuq used, second: based on the mention of he different sides of the two problems, third: based on the cause and background and the intention of furuq fiqhiyyah mentioned, fourth: based on the basis and origin of this furuq fiqhiyyah, and fifth: based on whether the two problems mentioned in this problem originate from one chapter of fiqh or come from different chapters
Preeklampsi Hastalarında Tam Kan Sayımı Parametrelerinin Önemi
Authors: KÜÇÜKYILDIZ İrem 
Published: August 2021

Amaç: Preeklampsi, gebeliğin 20. haftasından sonra saptanan; yeni başlangıçlı hipertansiyon ve organ disfonksiyonu ile karakterize, progresif, multisistemik bir hastalık olarak tanımlanmaktadr. Hafif ve şiddetli olmak üzere iki grupta değerlendirilebilen preeklapmsi özellikle şiddetli formunda ciddi maternal, fetal, neonatal morbidite ve mortalite ile ilişkli olabilmektedir. Bununla birlikte preeklampsi etyolojisi ve prediktör faktörleri hala tam olarak aydınlatılabilmiş değildir. Biz çalışmamızda tam kan sayımı parametrelerinin preeklampsi tanısı ve şiddetini belirlemedeki önemini tespit etmeyi amaçladık.
Araçlar ve Yöntemler: Çalışmaya 20 preeklamptik gebe ve 30 preeklampsinin eşlik etmediği sağlıklı gebe dahil edildi. Maternal ve fetal veriler ile birlikte doğum öncesi gebelerden rutin alınan tam kan sayımı parametreleri gruplar arasında karşılaştırıldı. Bu parametreler hemoglobin, trombosit sayısı, ortalama trombosit hacmi, lökosit-lenfosit sayısı ve trombosit /MPV, nötrofil/lenfosit trombosit/lenfosit, trombosit /nötrofil oranlarını kapsamaktadır.
Bulgular: Çalışmamızda değerlendirilen kadınların ortalama yaşları preeklampsi grubunda 30 (±13,5) kontrol grubunda 27(±11) idi. Kan sayımı parametreleri incelendiğinde; preeklampsi grubunda kontrol grubundan daha yüksek hemoglobin düzeyi tespit edilir iken; şiddetli preeklampsi grubunda ortalama trombosit hacminin hafif preklampsi grubu ve kontrol grubundan anlamlı olarak daha yüksek olduğu saptandı.
Sonuç: Çalışmamızda şiddetli preklampsinin eşlik ettiği gebelerde ortalama trombosit hacminin daha yüksek olduğu saptandı. Bununla birlikte, inflamatuar markır olarak kabul edilebilen nötrofil/lenfosit, trombosit/lenfosit oranlarının gruplar arasında fark göstermediği bulundu.
THE UTILITY OF PULSATILITY INDEX AND DIASTOLIC NOTCH PRESENCE IN UTERINE ARTERY DOPPLER ULTRASOUND BETWEEN 18-24 WEEKS FOR PREEKLAMPSIA PREDICTION’
Authors: GÖNCÜ AYHAN Şule , ARISOY Resul , MİHMANLI Veli 
Published: August 2021

Aim: To determine second-trimester uterine artery pulsatility index (UA-PI) values and diastolic notch (DN) presences in primigravid, low-risk pregnant women for preeclampsia (PE) prediction.
Matherials and Methods: We studied prospectively primigravid, pregnant women between 18 and 24 weeks of gestation who were admitted for routine prenatal care. An ultrasound examination that included measurements of the UA-PI and DN presence was performed and pregnancy outcomes were evaluated.
Results: In total 244 primigravid pregnant women were included this study, and 15 (6,1 %) developed PE. When Preeclampsia positive (PEP) group and the preeclampsia negative (PEN) group compared, there was no difference in demographic data. PEP group mean UA-PI value was significantly higher (p< 0,01) when mean time of the delivery week (p< 0,01) and fetal birth weight (p< 0,01) were significantly lower than PEN group.
DN was negative (NN) in 163 (66,8 %) pregnant women, and found positive (NP) in 81 (33,2%) pregnant women. NP group had higher PE rates compared to NN group. Bilateral notch positivity increases both PE and early PE rates compared to notch negativity and unilateral notch positivity. The most sensitive and specific value of UA-PI for PE prediction was found 1,13.
Conclusion: Uterine artery Doppler is a non-invasive and simple tool to identify high-risk pregnancies and may improve patient-specific practice. Especially pregnant women with a bilateral uterine notch accompanying with abnormal UA-PI values resulted a higher prevalence to develop these severe adverse outcomes. Closer monitoring may help to reduce both maternal and fetal morbidity and mortality in high-risk groups.
Illuminating Black Hole Subsystems in Young Star Clusters
Authors: Kaaz Nicholas , Kremer Kyle , Auchettl Katie , Ramirez-Ruiz Enrico 
Published: August 2021

Abstract
There is increasing evidence that globular clusters retain sizeable black hole populations at present day. This is supported by dynamical simulations of cluster evolution, which have unveiled the spatial distribution and mass spectrum of black holes in clusters across cosmic age. However, black hole populations of young, high metallicity clusters remain unconstrained. Black holes hosted by these clusters mass segregate early in their evolutionary history, forming central subsystems of hundreds to thousands of black holes. We argue that after supernova feedback has subsided (≳50 Myr), the host cluster can accumulate gas from its dense surroundings, from which the black hole subsystem accretes at highly enhanced rates. The collective accretion luminosity can be substantial and provides a novel observational constraint for young massive clusters. We test this hypothesis by performing 3D hydrodynamic simulations where we embed discretized potentials, representing our black holes, within the potential of a massive cluster. This system moves supersonically with respect to a gaseous medium from which it accretes. We study the accretion of this black hole subsystem for different subsystem populations and determine the integrated accretion luminosity of the black hole subsystem. We apply our results to the young massive clusters of the Antennae Galaxies and find that a typical subsystem accretion luminosity should be in excess of ≈ 1040 erg s−1. We argue that no strong candidates of this luminous signal have been observed and constrain the subsystem population of a typical cluster in the Antennae Galaxies to ≲ 10–2 × 102 10 M
⊙ black holes, given that feedback does not significantly impede accretion and that the gas remains optically thin.
Supermassive Star Formation in Magnetized Atomic-cooling Gas Clouds: Enhanced Accretion, Intermittent Fragmentation, and Continuous Mergers
Authors: Hirano Shingo , Machida Masahiro N. , Basu Shantanu 
Published: August 2021

Abstract
The origin of supermassive black holes (with ≳109
M
⊙) in the early universe (redshift z ∼ 7) remains poorly understood. Gravitational collapse of a massive primordial gas cloud is a promising initial process, but theoretical studies have difficulty growing the black hole fast enough. We focus on the magnetic effects on star formation that occurs in an atomic-cooling gas cloud. Using a set of three-dimensional magnetohydrodynamic simulations, we investigate the star formation process in the magnetized atomic-cooling gas cloud with different initial magnetic field strengths. Our simulations show that the primordial magnetic seed field can be quickly amplified during the early accretion phase after the first protostar formation. The strong magnetic field efficiently extracts angular momentum from accreting gas and increases the accretion rate, which results in the high fragmentation rate in the gravitationally unstable disk region. On the other hand, the coalescence rate of fragments is also enhanced by the angular momentum transfer due to the magnetic effects. Almost all the fragments coalesce to the primary star, so the mass growth rate of the massive star increases due to the magnetic effects. We conclude that the magnetic effects support the direct collapse scenario of supermassive star formation.
Thermophysical Investigation of Asteroid Surfaces. I. Characterization of Thermal Inertia
Authors: MacLennan Eric M. , Emery Joshua P. 
Published: August 2021

Abstract
The thermal inertia of an asteroid is an indicator of the thermophysical properties of the regolith and is determined by the size of grains on the surface. Previous thermophysical modeling studies of asteroids have identified or suggested that object size, rotation period, and heliocentric distance (a proxy for temperature) are important factors that separately influence thermal inertia. In this work we present new thermal inertia values for 239 asteroids and model all three factors in a multivariate model of thermal inertia. Using multiepoch infrared data of this large set of objects observed by WISE, we derive the size, albedo, thermal inertia, surface roughness, and sense of spin using a thermophysical modeling approach that does not require a priori knowledge of an object’s shape or spin axis direction. Our thermal inertia results are consistent with previous values from the literature for similarly sized asteroids, and we identify an excess of retrograde rotators among main-belt asteroids <8 km. We then combine our results with thermal inertias of 220 objects from the literature to construct a multivariate model and quantify the dependency on asteroid diameter, rotation period, and surface temperature. This multivariate model, which accounts for codependencies between the three independent variables, identifies asteroid diameter and surface temperature as strong controls on thermal inertia.
Anoplophora huangjianbini sp. n. from Fujian and Guangxi, China (Coleoptera: Cerambycidae: Lamiinae)
Authors: Wang Cheng-Bin , He Li 
Published: August 2021

The genus Anoplophora Hope, 1839 (Coleoptera: Cerambycidae: Lamiinae: Lamiini) includes 47 species (without subspecies) occurring in East, South and Southeast Asia. Amongst them, 38 species are known from CHINA. Members of this genus are familiar to Chinese people with a widely-used common name: “星天牛 [starry longhorn beetle]”. Anoplophora species have great economic importance, attacking and damaging numerous hardwood trees and some coniferous trees.
A new species of starry longhorn beetle, Anoplophora huangjianbini sp. n. (Coleoptera: Cerambycidae: Lamiinae: Lamiini) is described from Fujian and Guangxi, CHINA. Diagnostic characters of the new species are illustrated and comparison with closely-related congeners is provided.