bluuebunny/crossref_metadata_2025_split huggingface dataset:
DESIGN OF CONTROLLED RELEASE MUCOADHESIVE BUCCAL TABLETS OF IVABRADINE HCL USING SINTERING TECHNIQUE
Authors: MOHANTY CHANDAN , SUBRAHMANYAM K. V. 
Published: July 2021

Objective: The objective of the present work was to study the use of the sintering technique, a relatively new concept in pharmaceutical sciences, in the development of mucoadhesive buccal tablets for ivabradine Hydrochloride.
Methods: The method consisted of blending drug, hydroxypropyl methylcellulose (HPMC K100M), carnauba wax, and other excipients followed by direct compression into tablets. The compressed fluffy matrices were sintered at two different constant temperatures like 50 °C and 60 °C for two different periods like 1.5 h and 3 h in a hot air oven. The effect of sintering on tensile strength, dissolution profile, and other parameters were studied. The drug-polymer-excipient compatibility was evaluated by Fourier transform Infrared (FTIR) and differential scanning calorimetric (DSC) studies.
Results: The sintering condition markedly affected the drug release properties, hardness, and friability of the tablets. Based on the f2 similarity factor value, Ex-vivo mucoadhesive strength, Ex-vivo residence time, and in vitro dissolution studies, formulation F3SD was selected as an optimized formulation. Drug release followed a non-Fickian diffusion mechanism with the Higuchi model release kinetics. Stability studies of mucoadhesive buccal tablets in normal human saliva indicated the stability of the drug and buccal tablet in the oral cavity. Stability studies as per ICH guidelines revealed that optimized formulation was stable on storage conditions.
Conclusion: The sintering technique provides a significant and convenient method for the development of a controlled release dosage form that can be used in the design of mucoadhesive buccal tablets of Ivabradine HCL.
Acocoré: um projeto de resistência à pandemia ou arte em tempos telepresença.
Authors: Medeiros Maria Beatriz de 
Published: July 2021

RESUMO: O presente texto apresenta o projeto Acocoré (Arte, Coletivos, Conexões e Redes) realizado em telepresença desde julho de 2020, isto é, durante uma pandemia. Acocoré foi uma ideia, um movimento, e, de repente, (e)vento: site, performances, entrevistas, vídeos, isto é, movimento diruptivo fazendo História.

PALAVRAS-CHAVE: Acocoré, Arte, Coletivos, Conexões, Redes.
Chronic viral hepatitis B and D in pregnant women: course and outcomes (review)
Authors: Akhmedova M. D. , Tashpulatova Sh. A. , Ikhtiyarova G. A. , Karimova M. T. 
Published: July 2021

Hepatitis B is most common among young people, which is explained by the ways of infection – parenteral, sexual and vertical. Mother-to-child transmission is the main route of infection for children in areas where the hepatitis B virus (HBV) is endemic.The available current data on the course and outcomes of chronic viral hepatitis B are contradictory in pregnant women. Some authors argue that the exacerbation of chronic hepatitis B is more common in the first and third trimesters in pregnant women, and with an increase in gestation, there is a deterioration in liver function and an increased risk of fulminant liver failure. Other researchers note a more severe course in the second half of pregnancy or in the first months after delivery.High replication of the virus increases the frequency of gestational diabetes mellitus, hemostatic disorders, the threat of termination of pregnancy, gestosis, fetoplacental insufficiency, risk of bleeding in childbirth, premature birth, untimely discharge of amniotic fluid, and the birth of premature babies.Children become chronic carriers of HBsAd in neonatal hepatitis. These findings suggest that transplacental infection before birth may be a mechanism contributing to higher rates of failed prevention in newborns born to women with a high viral load.We could not find data on the features of the course and outcomes of viral hepatitis D in pregnant women in the available sources,. At the same time, it is known that mixed infection is more severe.Polymorphisms of genes associated with the regulation of the state of the vascular wall can have a significant impact on the course of infection.The high prevalence of hepatitis D infection in different parts of the world indicates the need for a comprehensive study of this disease, followed by the development of special programs for the prevention, early diagnosis and treatment of hepatitis B and D in pregnant women.
Comparison of factors influencing liquidity of European Islamic and conventional banks
Authors: Musa Hussam , Musova Zdenka , Natorin Viacheslav , Lazaroiu George , Martin Boda Martin 
Published: July 2021

Research background: The innovation in Shar??ah-compliant banking products has resulted in the rapidly increasing size of assets in Islamic banks worldwide. The assets of such banks have been growing twice as fast as those of conventional banks. Islamic banks do not depend on conventional interest, speculation, or complex derivatives stemming from banking operations. Instead, their actions in respect of profit/risk sharing, and the clarity of the contract are consistent with Islamic Shar??ah principles, which seek to promote a more equal society.
Purpose of the article: This research aims to identify and compare factors influencing the liquidity of Islamic and conventional banks in Europe. Candidate factors are sought amongst profitability, credit quality, credit expansion and capital adequacy indicators.
Methodology: First, relevant financial ratios for 249 observations on Islamic banks and 2,306 observations on conventional banks are selected and compared for the period 2013?2017. Second, liquidity is explained separately for each type of banks by panel data regression to identify its determinants in a comparative context.
Findings & value added: The results indicate that the impact of the net interest margin on the liquidity ratio of Islamic banks is insignificant, which is obviously due to the prohibition of the use of interest (riba). To the contrary, in conventional banking a higher net interest margin results in a reduction in liquidity. Capital adequacy has a positive influence upon liquidity in both types of banks, but in Islamic banking, the influence is 5.4 times greater. The findings strongly suggest that the liquidity of Islamic and conventional banks is affected by different factors.
TREATMENT OF TRADITIONAL ETHANOL FERMENTATION WASTE WITH ELECTROLYSIS METHOD FOR DECREASING COD AND SULFIDE
Authors: Saputro Dimas Eko , Fatimah Siti 
Published: July 2021

Ethanol is produced from molasses by a fermentation process. In Bekonang, ethanol manufacturingby a home-scale industry so the waste just thrown away in free water then pollution occurs both in rivers and in paddy fields. Ethanol waste has very high chemical oxygen demand (COD) and contain high sulfide. Electrolysis that use for reduce leves COD dan Sulfide with electricity as main source for direct current flowing electricity (dc) to the anode and cathode. Electrolysis time 10, 15, 20, 25 and 30 minutes and voltage variation 5, 10 and 15 volt. Based on data obtained in the test COD obtained optimum levels of 284.5 mg/L from the initial content of 586 mg/L , at a time variation of 30 minutes and voltage 15 volt. The sulfide test obtained optimum levels of 0.0661 mg/L from the initial content of 0.305 mg/L, at time variation of 25 minutes and a voltage of 15 volt.
Estimación de mestizaje en dos poblaciones venezolanas usando marcadores informativos de ancestralidad y haplogrupos de ADN mitocondrial
Authors: Rodríguez Álvaro , Flores-Gutiérrez Sara , Fernández Gil Liana , Paradisi Irene , Antonelli Giulianna , Castro de Guerra Dinorah 
Published: July 2021

Los marcadores informativos de ancestralidad (AIM) autosómicos y los del ADN mitocondrial (ADNmt) son muy útiles para identificar el origen y los patrones de migración de las poblaciones. En este trabajo se estimó el mestizaje a partir de siete AIM en 188 individuos venezolanos, 84 del estado Guárico y 104 de la región centro occidental de Venezuela (RCO), se estimó la ancestralidad mitocondrial en el estado Guárico y se compararon ambas poblaciones según su origen y desarrollo histórico. Este estudio representa la primera aproximación a la composición genética de Guárico y es el primer reporte para Venezuela utilizando marcadores tipo AIM. Los resultados revelaron que los aportes amerindio y europeo predominan en estas poblaciones, pero el amerindio es mayor en Guárico (50,57 %) que en RCO (44,92 %), y el europeo lo es en RCO (38,46 % vs. 33,72 %). El origen del ADNmt en Guárico es de predominio amerindio (80 %), tendencia similar a lo reportado para RCO (75 %). El aporte amerindio en Guárico es el más alto reportado para Venezuela. Se concluye que las diferencias encontradas entre ambas muestras podrían deberse a la colonización más temprana de la RCO y a su desarrollo industrial moderado durante el siglo XIX. Así mismo, planteamos que los AIM aquí utilizados lograron una buena discriminación del aporte de los tres grupos ancestrales principales y que su uso simultáneo con polimorfismos de origen uniparental permite obtener, en forma económica, una mejor aproximación genética para explicar la dinámica del proceso de mestizaje que dio origen a la población venezolana actual.
Hipertensión arterial, exceso de peso y obesidad abdominal en mujeres adultas de la Puna de Catamarca, Argentina
Authors: Menecier Natalia , Lomaglio Delia Beatriz 
Published: July 2021

La hipertensión arterial (HTA) y la obesidad son problemas crecientes y de riesgo para el desarrollo de enfermedades crónicas, por ejemplo, el síndrome metabólico, entre otras. Son escasos los datos relativos a poblaciones de altura de América del Sur. El objetivo fue analizar las prevalencias de exceso de peso, obesidad abdominal e hipertensión arterial en mujeres adultas, residentes permanentes a más de 3000 msnm, de dos localidades de población concentrada de la Puna de Catamarca, Argentina. Se analizaron 105 mujeres adultas, de la villa de Antofagasta de la Sierra y El Peñón, de Antofagasta de la Sierra, Catamarca. Se obtuvieron las medidas de peso, talla, perímetro de cintura y valores de presión arterial sistólica (PAS) y diastólica (PAD). Se calculó el índice de masa corporal (IMC) e índice cintura-talla (ICT). El sobrepeso representó el 38,1%, la obesidad el 17,1% y la obesidad abdominal el 84%. La prevalencia de hipertensión arterial fue de 16,2%. Existe una correlación positiva entre IMC y la PAS, y entre la edad y la PAD. Los valores de PAS fueron significativamente mayores en mujeres con obesidad, respecto a aquellas con normopeso. No hubo diferencias de PAD según las categorías de estado nutricional. A su vez en mujeres normopesas no se observaron diferencias en los valores de PAS y PAD en presencia o ausencia de obesidad abdominal. La diferencia entre HTA en presencia de exceso de peso y obesidad abdominal no es significativa, y tampoco difiere en mujeres con normopeso con y sin obesidad abdominal. Conclusión: las mujeres adultas analizadas presentaron altas prevalencias de exceso de peso compatible en un contexto de transición nutricional. A su vez 9 de cada 10 mujeres presentaron obesidad abdominal junto a bajas prevalencias dehipertensión arterial sin relación entre ellas. Se comprobó asociación sólo entre HTA y obesidad.
Dios y el hombre en la filosofía del humanismo burgués contemporáneo
Authors: De Juan Fernandez Jorge 
Published: July 2021

El hombre burgués traduce su “ser” por “tener”. Esto trae consigo la formación de una idea errónea de la Trascendencia, ya que en el planteamiento filosófico, el problema Dios está condicionado por la antropología. Junto a ello, se producirá una desviación de los valores comunitarios del hombre y de las relaciones humanas.
El presente artículo se presenta como una llamada urgente a impulsar un nuevo humanismo que corrija el desequilibrio entre el mundo del “ser” y el del “tener” y fomente el desarrollo íntegro de la vocación personal.
PENGARUH BOREDOM PRONENESS DAN LOCUS OF CONTROL TERHADAP KECEPATAN SAAT MENGEMUDI DI JABODETABEK
Authors: Prajitna Gavriel Ganesia , Putranto Leksmono Suryo 
Published: July 2021

Driving is an activity that contains a high risk such as loss, damage, loss, accidents and even death, so the drivers requires full attention with very high concentration. One of the causes of accidents experienced by some drivers is the result of several internal factors from the driver, one of the factors is boredom proneness. To be able to control all factors while driving, of course, good control skills are needed for the driver. One of the constructs that is able to explain this is the locus of control. In terms of driving on the road, drivers must also pay attention to personal safety by paying attention to vehicle speed. This research was conducted to determine the effect of locus control on boredom prone, boredom prone to speed, and control locus on speed. Data for research were obtained through online questionnaires. This research will be the method of Structural Equation Modeling (SEM). From the research results, it was found that the boredom proneness greatly affects a person's choice of speed. Meanwhile, the locus of control is a factor that slightly affects a person's speed selection. In addition, the locus of control is sufficient to affect a person's boredom proneness nature ABSTRAKMengemudi merupakan kegiatan yang mengandung resiko tinggi seperti kerugian, kerusakan, kehilangan, kecelakaan bahkan kematian, dengan demikian pengemudi membutuhkan perhatian penuh dengan konsentrasi sangat tinggi. Salah satu penyebab kecelakaan yang dialami beberapa pengemudi adalah akibat beberapa faktor internal dari pengemudi tersebut, salah satu faktor nya adalah rawan bosan. Untuk dapat mengontrol semua faktor ketika mengemudi, tentu dibutuhkan kemampuan kontrol yang baik pada pengemudi. Salah satu konstruk yang mampu menjelaskan hal tersebut yaitu lokus kendali. Dalam hal mengemudi di jalan, pengemudi juga harus memperhatikan keselamatan diri dengan memperhatikan kecepatan kendaraan. Penelitian ini dilakukan untuk mengetahui pengaruh lokus kendali terhadap rawan bosan, rawan bosan terhadap kecepatan, dan lokus kendali terhadap kecepatan. Data untuk penelitian didapatkan melalui kuesioner secara online. Penelitian ini akan Metode Structural Equation Modeling (SEM). Dari hasil penelitian didapatkan bahwa rawan bosan sangat mempengaruhi pilihan kecepatan seseorang. Sedangkan lokus kendali merupakan faktor yang sedikit mempengaruhi pemilihan kecepatan seseorang. Selain itu lokus kendali cukup mempengaruhi sifat rawan bosan seseorang.
ANALISIS PENGARUH PEMODELAN SAMBUNGAN TITIK BUHUL PADA STRUKTUR KUBAH GEODESIK
Authors: Meilvin Rivven , Tedianto Leo S. 
Published: July 2021

The geodesic dome consists of steel rod elements joined together to form a single structure. Generally, these geodesic domes are analyzed by assuming the joints of the gusset points are joints and only receive axial forces on the rods. However, in reality, it is not easy to apply gusset joints as pure joints in construction. This research will analyze the geodesic dome by modeling the joints of the gusset points as joints where there is only axial force arising on the rods and modeling the rigid gusset points where there will also be moments and shear on the rods. The analysis will only be carried out by comparing the value of the displacement at each gusset joint modeling and checking the cross-sectional dimensions of the internal forces that arise with the help of the MIDAS GEN program in modeling the geodesic dome structure which has a diameter of 20000 mm and a height of 10000 mm with the type of steel profile. used is a pipe profile using two types of geodesic dome, namely type 2V and 3V. For loads that are calculated, namely dead load, live load, and wind load. The results showed a relatively small difference in translational displacement and the axial force was relatively the same in the internal force analysis, so it is better if the analysis by modeling the gusset connection as rigid.ABSTRAKKubah geodesik terdiri dari elemen batang baja yang disambung menjadi satu kesatuan struktur. Umumnya kubah geodesik ini dianalisis dengan menganggap sambungan titik buhulnya berupa sendi dan hanya menerima gaya aksial saja pada batang - batangnya. Namun pada kenyataannya untuk mengaplikasikan sambungan titik buhul sebagai sendi murni pada konstruksi tidaklah mudah. Penelitian ini akan menganalisis kubah geodesik dengan memodelkan sambungan titik buhulnya sebagai sendi dimana hanya ada gaya aksial saja yang timbul pada batang - batangnya dan memodelkan titik buhulnya rigid dimana akan terjadi juga momen dan geser pada batang tersebut. Analisis hanya akan dilakukan dengan membandingkan nilai dari perpindahan pada setiap pemodelan sambungan titik buhul dan pengecekan dimensi penampang terhadap gaya – gaya dalam yang timbul dengan bantuan program MIDAS GEN dalam memodelkan struktur kubah geodesik yang mempunyai diameter 20000 mm dan tinggi 10000 mm dengan jenis profil baja yang digunakan adalah profil pipa dengan menggunakan dua tipe kubah geodesik yaitu tipe 2V dan 3V. Untuk beban yang diperhitungkan yaitu beban mati, beban hidup, dan beban angin. Hasil penelitian menunjukkan nilai perbedaan yang relatif kecil pada perpindahan translasi dan diperoleh gaya aksial yang relatif sama pada analisis gaya dalam yang timbul, sehingga sebaiknya analisis dengan pemodelan sambungan titik buhul sebagai rigid.
Morphological and biochemical properties of garlic (Allium sativum L.) collections
Authors: Tripathi P C , Jadhav H M , Qureshi A A , Sankar V , Mahajan V , Lawande K E 
Published: July 2021

Garlic (Allium sativum L.) is an important constituent of many of traditional medicines. The nutrient composition and biochemical ingredients of garlic vary among varieties and locations. The current experiment was conducted with 35 genotypes of garlic to study variation in morphological and biochemical properties among these genotypes. The weight of bulbs ranged from 6.9 g to 22.6 g. Highest number of clove bulb-1 was recorded in collection -286 (44.6) followed by GG-2 (40.6). Clove weight was higher in collection - 316 (1.41 g). The dry weight ranged from 28.6 per cent to 38.65 per cent. Highest total soluble solids were found in collection -79 (35.1°Brix). Potassium, iron and zinc content were higher in GG-2 (1.70%, 47 ppm and 19.2 ppm, respectively). Sulphur and copper content were higher in G-41. Manganese content ranged from 6.90 to 23.1 ppm. Highest anthocyanin pigment was found in the peel of cv. Godavari (5.35 mg). There was not much difference in anthocyanin content in pulp of purple and white colour varieties. Pyruvic acid content ranged from 20.9 µ mol ml-1 to 24.9 µ mol ml-1. Over all cvs. G-50, G-41, collection -316 were found superior over others.
Radiology Performed Fluoroscopy-Guided Lumbar Punctures Decrease Volume of Diagnostic Study Interpretation – Impact on Resident Training and Potential Solutions
Authors: Richards Tyler John , Schmitt James Eric , Wolansky Leo J. , Nayate Ameya P. 
Published: July 2021

Objectives:
Lumbar punctures performed in radiology departments have significantly increased over the last few decades and are typically performed in academic centers by radiology trainees using fluoroscopy guidance. Performing fluoroscopy-guided lumbar punctures (FGLPs) can often constitute a large portion of a trainee’s workday and the impact of performing FGLPs on the trainee’s clinical productivity (i.e. dictating reports on neuroradiology cross-sectional imaging) has not been studied. The purpose of the study was to evaluate the relationship between the number of FGLPs performed and cross-sectional neuroimaging studies dictated by residents during their neuroradiology rotation (NR).

Material and Methods:
The number of FGLPs and myelograms performed and neuroimaging studies dictated by radiology residents on our neuroradiology service from July 2008 to December 2017 were retrospectively reviewed. The relationship between the number of FGLPs performed and neuroimaging studies (CT and MRI) dictated per day by residents was examined.

Results:
Radiology residents (n = 84) performed 3437 FGLPs and myelograms and interpreted 33402 cross-sectional studies. Poisson regression demonstrated an exponential decrease in number of studies dictated daily with a rising number of FGLPs performed (P = 0.0001) and the following formula was derived: Number of expected studies dictated per day assuming no FGLPs × e-0.25 x number of FGLPs = adjusted expected studies dictated for the day.

Conclusion:
We quantified the impact performing FGLPs can have on the number of neuroimaging reports residents dictate on the NR. We described solutions to potentially decrease unnecessary FGLP referrals including establishing departmental guidelines for FGLP referrals and encouraging bedside lumbar punctures attempts before referral. We also emphasized equally distributing the FGLPs among trainees to mitigate procedural burden.
Haptic virtualisation of surfaces: feeling textiles on your phone
Authors: Braune Annerose , Martin Christopher , Le Tung 
Published: July 2021

The haptic impression of textile surface properties has a decisive influence on its evaluation and ultimately on its acceptance and usability. Many solutions are used to replicate a static contour or shape, e.g. to feel controls on common touch displays. In contrast, this project investigates whether it is possible to simulate the roughness or friction behaviour of a textile surface using a commercially available mobile device.
Drenagem de tórax em pacientes com COVID-19
Authors: Reinaldo Luis Gustavo Cavalcante , Alencar Auriane de Sousa , Leite Camila Botelho Campelo , Silva Ilana de Meneses , Martins Tarso Buaiz Pereira , Lima Maria de Fátima de Brito Coutinho Nogueira , Cardoso Virgínia Portela 
Published: July 2021

Objetivos: descrever a experiência e os resultados da equipe cirúrgica do Hospital Universitário da Universidade Federal do Piauí (HU UFPI) na realização de drenagem torácica na unidade de terapia intensiva (UTI) covid. Métodos: estudo retrospectivo que se analisou os prontuários médicos dos pacientes submetidos à drenagem torácica no período de abril a agosto de 2020. Durante esse período, 13 pacientes com exames positivos para Covid 19 foram submetidos ao procedimento. Variáveis estudadas: idade, gênero, indicação da drenagem de tórax, uso ou não de ventilação mecânica, desfecho (alta da UTI ou óbito). A drenagem de tórax foi realizada sempre por um residente de cirurgia geral, sob orientação de um cirurgião geral. Resultados: idade média dos pacientes foi de 67.7 anos, sendo que 69.2% eram do sexo masculino. A indicação mais frequente foi pneumotórax espontâneo com 61.5% dos casos, pneumotórax secundário 15.38% e derrame pleural em 15.38%. Uso de ventilação mecânica em 84.6%. Melhoria do padrão respiratório e da expansibilidade pulmonar ocorreu em 61.5%. Não houve complicações e mortalidade relacionada ao procedimento. Tais pacientes tiveram como desfecho óbito em 76.9% e melhora clínica em 23.1% dos casos. Conclusão: concluímos que a drenagem de tórax, quando realizado com base em protocolos, é segura e altamente eficaz para o tratamento de complicações pulmonares do Covid-19, como pneumotórax e derrame pleural.