bluuebunny/crossref_metadata_2025_split huggingface dataset:
Initial overcorrection after surgery for intermittent exotropia in children less than 4 years old: Comparison with older children
Authors: Choi Jinju , Choi Dong Gyu 
Published: September 2021

Purpose
While initial overcorrection after exotropia-correcting surgery is widely accepted for a favorable long-term outcome, some have not advocated such overcorrection in younger children owing to concerns regarding rapid deterioration of bifixation ability. This study aimed to evaluate the relationship between initial overcorrection after intermittent exotropia surgery and the surgical outcome in patients aged <4 years.

Methods
In this retrospective study, 391 patients who had undergone surgery for intermittent exotropia were classified into two groups according to the age at surgery: <4 years old (group Y [young], 130 patients) and 4–16 years old (group O [old], 261). The patients were subdivided into three groups according to the angle of deviation at postoperative 1 week: esophoria-tropia (ET) ≥10 prism diopters (PD) (subgroup I), ET 1–9 PD (II), and orthotropia or exophoria-tropia (XT) (III). We compared the surgical outcomes between the two groups and among subgroups; then, we analyzed consecutive esotropia patients.

Results
The mean exodeviation was smaller in the order of subgroup I, II, and III at every postoperative visit (p<0.05) in group Y but showed no difference among subgroups after 2 years in group O. Consecutive esotropia occurred at 1 month, postoperatively, in 6.9% and 2.6% of the patients in groups Y and O (p = 0.133), respectively. However, it persisted in two and one patient in groups Y and O, respectively, until the last visit.

Conclusion
Early overcorrection after intermittent exotropia surgery was a safe and desirable result in terms of motor outcome in children aged under 4 years, as well as for children aged between 4–16 years.
Inattentional blindness in anesthesiology: A gorilla is worth one thousand words
Authors: De Cassai Alessandro , Negro Sebastiano , Geraldini Federico , Boscolo Annalisa , Sella Nicolò , Munari Marina , Navalesi Paolo 
Published: September 2021

Introduction
People are not able to anticipate unexpected events. Inattentional blindness is demonstrated to happen not only in naïve observers engaged in an unfamiliar task but also in field experts with years of training. Anaesthesia is the perfect example of a discipline which requires a high level of attention and our aim was to evaluate if inattentional blindness can affect anesthesiologists during their daily activities.

Materials and methods
An online survey was distributed on Facebook between May 1, 2021 and May 31, 2021.
The survey consisted of five simulated cases with questions investigating the anesthetic management of day-case surgeries. Each case had an introduction, a chest radiography, an electrocardiogram, preoperative blood testing and the last case had a gorilla embedded in the chest radiography.

Results
In total 699 respondents from 17 different countries were finally included in the analysis.
The main outcome was to assess the incidence of inattentional blindness.
Only 34 (4.9%) respondents were able to spot the gorilla. No differences were found between anesthesiologists or residents, private or public hospitals, or between medical doctors with different experience.

Discussion
Our findings assess that inattentional blindness is common in anesthesia, and ever-growing attention is deemed necessary to improve patient safety; to achieve this objective several strategies should be adopted such as an increased use of standardized protocols, promoting automation based strategies to reduce human error when performing repetitive tasks and discouraging evaluation of multiple consecutive patients in the same work shifts independently of the associated complexity.
Effects of specific inspiratory muscle training combined with whole-body endurance training program on balance in COPD patients: Randomized controlled trial
Authors: Tounsi Bilel , Acheche Amal , Lelard Thierry , Tabka Zouhair , Trabelsi Yassine , Ahmaidi Said 
Published: September 2021

Purpose
This study aims to assess the effect of inspiratory muscle training (IMT) combined with endurance training (ET) on balance in patients with chronic obstructive pulmonary disease (COPD).

Methods
We studied 32 male patients (62 ± 6 years) with moderate to very severe COPD. They were randomly assigned to an experimental group (IMT+ET) n = 16 or a control group (ET) n = 16 with similar characteristics. The evaluations were carried out at inclusion and after eight weeks of the training period. Functional balance was assessed by the Berg Balance Scale (BBS), the Timed-up and Go (TUG), the Single Leg Stance test (SLS), and the Activities-specific Balance Confidence (ABC) scale. The strength of the inspiratory muscles (PImax) was assessed by maximal inspiratory mouth pressure. Functional exercise performance was assessed by the 6 minutes walking test (6MWT). IMT program consists in performing two daily sets of 30 inspirations with 50% of PImax increased by 10% every two weeks. ET program consists in performing 30 min treadmill exercise at 60% to 80% of the average speed achieved during the 6MWT three days per week.

Results
After the training period, the experimental group demonstrated greater improvements in BBS (IMT+ET vs. ET; p = 0.019), and in ABC (IMT+ET vs. ET; p = 0.014). However, no significant differences between groups were observed for TUG, SLS, and 6MWT. There was a significant difference between groups in PImax (IMT+ET vs. ET; p = 0.030). Significant moderate correlations were obtained between ΔPImax and ΔBBS for both groups (IMT+ET: r = 0.624, p = 0.010; ET r = 0.550, p = 0.027) as well as for ΔABC but only in the experimental group (IMT+ET: r = 0.550, p = 0.027).

Conclusion
Compared to ET alone, the results suggest that IMT combined with ET enhances inspiratory muscle function and functional balance according to BBS and ABC in patients with COPD. We suggest that inspiratory muscle training might be introduced as additional training to pulmonary rehabilitation programs aimed at improving balance in COPD patients.

Trial registration
The trial registry name: Clinical Trials; Registration number: NCT04084405; URL: https://clinicaltrials.gov/ct2/show/NCT04084405.
Small incision lenticule extraction (SMILE) combined with allogeneic intrastromal lenticule inlay for hyperopia with astigmatism
Authors: Zhang Jing , Zhou Yuehua 
Published: September 2021

Purpose
To quantitatively evaluate outcomes after small incision lenticule extraction (SMILE) combined with allogeneic intrastromal lenticule inlay for hyperopia with astigmatism.

Methods
It’s a retrospective cohort study. Twenty-four eyes of 15 patients with more than 0.75 diopters (D) of astigmatism in hyperopic eyes were enrolled in this study. The hyperopic eye with astigmatism was first treated with SMILE to correct astigmatism; then a lenticule was extracted from a donor myopic eye and subsequently implanted into the hyperopic eye with astigmatism. Patients were examined preoperatively and 1 day, 1 week, 1,3 months and 1 year after surgery. The main outcome measures were the uncorrected and corrected distance visual acuity (UDVA and CDVA), uncorrected near visual acuity (UNVA), spherical equivalent (SE), corneal topography, anterior segment optical coherence topography (OCT) and ocular response analyzer (ORA) parameters: corneal hysteresis (CH) and corneal resistance factor (CRF). Repeated–measures analyses of variance (ANOVA) and post hoc tests were used to analyze data of different follow-up visits.

Results
The mean preoperative cylinder was 1.95±1.04(D). The UDVA (from 0.37±0.23 to 0.09±0.09), UNVA (from 0.49±0.21 to 0.08±0.06), SE (from +7.42±3.12 to -0.75±0.79) and astigmatism (+1.95±1.04 to -0.65±0.63) postoperatively were obviously better than those before surgery. Five eyes (26.3%) gained one line of CDVA, and 3 eyes (15.8%) gained two lines of CDVA one year after surgery compared with preoperative levels. The average corneal curvature was changed from (43.19±4.37) D to (49.19±3.87) D one year after surgery. The anterior segment OCT images of corneas with lenticule inlays at each follow-up visit showed that the implanted lenticule was shaped like a crescent in the corneal stroma. The CH and CRF didn’t change significantly after surgery (p = 0.189 and p = 0.107respectively).

Conclusions
SMILE combined with intrastromal lenticule inlay can be used to correct high hyperopia with astigmatism with good safety, efficacy and reproducibility.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence: Navigating the absence of a gold standard
Authors: Saeed Sahar , O’Brien Sheila F. , Abe Kento , Yi Qi-Long , Rathod Bhavisha , Wang Jenny , Fazel-Zarandi Mahya , Tuite Ashleigh , Fisman David , Wood Heidi , Colwill Karen , Gingras Anne-Claude , Drews Steven J. 
Published: September 2021

BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence studies bridge the gap left from case detection, to estimate the true burden of the COVID-19 pandemic. While multiple anti-SARS-CoV-2 immunoassays are available, no gold standard exists.MethodsThis serial cross-sectional study was conducted using plasma samples from 8999 healthy blood donors between April-September 2020. Each sample was tested by four assays: Abbott SARS-Cov-2 IgG assay, targeting nucleocapsid (Abbott-NP) and three in-house IgG ELISA assays (targeting spike glycoprotein, receptor binding domain, and nucleocapsid). Seroprevalence rates were compared using multiple composite reference standards and by a series of Bayesian Latent Class Models.ResultWe found 13 unique diagnostic phenotypes; only 32 samples (0.4%) were positive by all assays. None of the individual assays resulted in seroprevalence increasing monotonically over time. In contrast, by using the results from all assays, the Bayesian Latent Class Model with informative priors predicted seroprevalence increased from 0.7% (95% credible interval (95% CrI); 0.4, 1.0%) in April/May to 0.7% (95% CrI 0.5, 1.1%) in June/July to 0.9% (95% CrI 0.5, 1.3) in August/September. Assay characteristics varied over time. Overall Spike had the highest sensitivity (93.5% (95% CrI 88.7, 97.3%), while the sensitivity of the Abbott-NP assay waned from 77.3% (95% CrI 58.7, 92.5%) in April/May to 64.4% (95% CrI 45.6, 83.0) by August/September.DiscussionOur results confirmed very low seroprevalence after the first wave in Canada. Given the dynamic nature of this pandemic, Bayesian Latent Class Models can be used to correct for imperfect test characteristics and waning IgG antibody signals.
Three Films by Luis Buñuel
Authors: DeAtley Morgan 
Published: September 2021

The Discreet Charm of the Bourgeoisie (1972)
France
Director Luis Buñuel
Runtime 101 minutes

The Phantom of Liberty (1974)
France
Director Luis Buñuel
Runtime 103 minutes

That Obscure Object of Desire (1977)
France
Director Luis Buñuel
Runtime 104 minutes

Blu-ray
USA, 2021
Distributed by The Criterion Collection (region A)
Ukrepi za obravnavo otroka z okužbo zgornjih dihalnih poti
Authors: Cilar Leona , Kegl Barbara , Pajnkihar Majda , Stričević Jadranka , Marčun Varda Nataša , Klanjšek Petra 
Published: September 2021

Uvod: Okužbe zgornjih dihalnih poti so pri otrocih pogoste ter so tudi pogost razlog za opustitve šolanja, obisk zdravnika in nepotrebne stroške zdravstva. Namen raziskave je pregledati, analizirati in sintetizirati obstoječo literaturo s področja ukrepov pri zdravstveni obravnavi otrok z okužbo zgornjih dihalnih poti.Metode: Uporabili smo opisno metodo dela. Iskanje literature je potekalo v obdobju od decembra 2019 do januarja 2020 v mednarodnih podatkovnih bazah Medline in CINAHL. Potek iskanja in analize literature je prikazan s pomočjo diagrama PRISMA. Zadetke smo analizirali glede na karakteristike raziskav in razvrstili glede na raven dokaza. Rezultate smo sintetizirali s pomočjo vsebinske analize.Rezultati: Izmed 1.845 identificiranih zadetkov smo v končno analizo vključili 18 zadetkov. Identificirali smo 10 kategorij: znanje, prepoznavanje okužbe zgornjih dihalnih poti, predpisovanje in uporaba antibiotikov, uporaba nepredpisanih zdravil v domačem okolju, uporaba predpisanih zdravil v domačem okolju, uporaba predpisanih zdravil v bolnišnici, socialna izolacija, nedokazan uspeh zdravila, dejavnosti zdravstvenih delavcev za preprečevanje ali zdravljenje okužb zgornjih dihalnih poti, obravnava, osredotočena na otroka in starše. Identificirali smo tri kategorije: zdravstvena vzgoja, zdravljenje in ukrepi za izboljšanje zdravstvene obravnave, zdravstvena nega in oskrba.Diskusija in zaključek: Za kakovostno zdravstveno obravnavo otrok z okužbami zgornjih dihalnih poti je potreben pristop, ki je usmerjen k otroku in družini, je celosten ter varen. Ukrepi pri interdisciplinarni zdravstveni obravnavi otrok morajo temeljiti na znanstvenih dokazih. Poleg ustreznega zdravljenja in ukrepov je pomembno, da izvajamo tudi izobraževanje otrok in staršev.
Three-dimensional metallic carbon allotropes with superhardness
Authors: Fan Qingyang , Liu Heng , Jiang Li , Zhang Wei , Song Yanxing , Wei Qun , Yu Xinhai , Yun Sining 
Published: September 2021

Abstract
Three novel three-dimensional orthorhombic carbon phases are proposed based on first-principles calculations in this work. These phases possess dynamic stability and mechanical stability and are theoretically more favorable in energy compared to most other carbon allotropes. The hardness levels of oP-C16, oP-C20, and oP-C24 are 47.5, 49.6, and 55.3 GPa, respectively, which are greater than those of T10, T18, and O12 carbon. In addition, although oP-C16, oP-C20, and oP-C24 are metals, their ideal shear strengths are also greater than those of common metals such as Cu, Fe, and Al. Due to p

y
electrons crossing the Fermi level, oP-C16, oP-C20, and oP-C24 show metallicity, and their charge densities of the band decomposition suggest that all the conductive directions of oP-C16, oP-C20, and oP-C24 are exhibited along the a- and b-axis, similar to C5.
Research progress on individual effect of graphene oxide in cement-based materials and its synergistic effect with other nanomaterials
Authors: Liu Changjiang , Chen Fulian , Wu Yuyou , Zheng Zhoulian , Yang Jingwei , Yang Bo , Yang Jiangying , Hui David , Luo Yuanbing 
Published: September 2021

Abstract
Poor crack resistance, high brittleness, and poor toughness are inherent limitations of traditional cement-based materials. Besides, cement-based materials have certain shortcomings in energy consumption and environmental protection. Therefore, improving the performance of cement-based materials becomes a hot topic in related research. At the same time, the development of nanomaterials and technologies provides researchers with a new research idea: to enhance the performance of cement-based materials at the nanoscale level. Graphene oxide (GO) is one of the most representative nano-reinforcements. Due to its high surface area and excellent physical properties, GO has a surprising effect on improving the performance of cement-based materials. In addition, nanosilica (NS) and carbon nanotubes (CNTs) have excellent improvement on cement-based materials, and people also hope to further improve the performance of cement-based materials through the interaction of various nanomaterials. In this paper, the influence of GO on cement-based materials is reviewed by consulting a lot of correlative literature, mainly focusing on the following aspects: (i) The dispersion of GO in cement paste. (ii) The influence of GO on the properties of cement-based materials, including working performance, mechanical strength, microstructural characteristics, and durability. (iii) The effect of nanohybrid materials of GO, NS, and CNTs on cement-based materials, and the synergistic effects of various nanomaterials are reviewed for the first time. (iv) Evaluation of current progress. This paper aims to provide guidance for the study and application of GO-modified cement-based materials and nanohybrid materials.
Catalytic defense against fungal pathogens using nanozymes
Authors: Qingzhi Wu , Zou Sijia , Wang Qian , Chen Lei , Yan Xiyun , Gao Lizeng 
Published: September 2021

Abstract
Fungal infections are still a major challenge for clinics, resulting from the resistance of drug-resistant fungi and the toxicity of antifungal drugs. Defense against fungal invasions via enzymatic catalysis has been found in nature. The use of nanozymes, as artificial enzyme mimics, may be a promising strategy to induce fungal death due to their advantages such as tunable catalytic activity, high stability, low cost, and easy preparation. Here, the importance of natural enzymes in the defense against fungi is outlined. The progress in antifungal performance and potential application of nanozymes and the related antifungal mechanisms are also summarized. Finally, the perspective and challenges in this field for future study, pointing out that nanozyme-based catalytic therapy represents a promising alternative strategy for antifungal treatment, are highlighted.
Enantiomeric purity deviations of radiolabelled amino acids obtained from chiral columns
Authors: Fedorova Olga , Nadporojskii Michail , Krasikova Raisa 
Published: September 2021

Abstract
Enantiomeric purity (EP) is an important value which denotes the relative percentage of the L-isomer with respect to the D-isomer. For 11C and 18F-labelled amino acid (AA) radiopharmaceutical (RP) production, EP represents a quality control parameter specified in European and national monographs for particular RPs. In most instances, EP value of greater then 90 or 95% (depending on AA type) is required as part of the quality control (QC) value of a RP following radiosynthesis. In common practice, two chromatographic columns are used for the EP determination of RPs: Crownpak CR(+) (Daicel), which contains a crown ether stationary phase or Chirobiotic T (Astec), which contains silica-bound glycoproteins as the stationary phase. The application of column Crownpak CR(+) requires that only perchloric acid solution (with pH 1–2) may be used, as the retention capability of the stationary phase is greatly reduced using organic solvents. This work intends to identify which chromatographic system is more accurate and reliable for EP determination as part of QC. We performed a series of parallel injections of the same batch of the widely used AA RPs [11C]MET and [18F]FET on the two aforementioned columns. The EP determination using column Crownpak CR(+) consistently provided a lower EP value compared to the Chirobiotic T column; the EP deviation between the respective columns was found to range from 2.4–4.0% for the same RP sample. Furthermore, the EP value was influenced by a sample’s dilution factor, e.g. the EP was observed to increase up to 1.5% when the radioactive sample had a fivefold dilution factor. This phenomenon was consistent for both Crownpak CR(+) and Chirobiotic T columns. Finally, a series of standard solutions of non-radioactive methionine with various ratios of L-and D-isomers was analyzed. The data obtained for non-radioactive methionine confirmed that column Crownpak CR(+) incorrectly provided a higher D-enantiomer concentration, whereas Chirobiotic T was found to provide a lower D-enantiomer concentration of the same sample. The deviation from the theoretical EP value was between 0.67 and 1.92%.
Beryllium oxide nanoparticles: synthesis, characterization, and thermoluminescence evaluation for gamma radiation detection
Authors: Faraji Shadi , Feizi Shahzad , Sabouri Dodaran Amir Abbas , Alipour Anita , Ashtari Parviz , Sharbatdaran Masoumeh 
Published: September 2021

Abstract
In this study, beryllium oxide nanoparticles (BeO NPs) were synthesized by polymer-gel method with schlenk line. The products were then assessed using FESEM, TGA/DSC, XRD and BET analyses. The quality of two nanooxides, that were calcined at 700 and 800 °C, was studied and compared with bulk BeO particles. The results showed that nanoparticles calcined at 800 °C were more uniform and had ellipsoidal morphology with a particle size of ∼35 nm. Investigation thermoluminescence (TL) characteristics of BeO NPs showed that with the decreasing exposed dose/increasing the BeO particle size, TL peaks were observed at higher temperatures. The intensities of glow curves increase linearly with the increasing absorbed dose in the range of 0.001 mGy–1000 Gy. Various other studies including response fading, minimum temperature and minimum time for annealing, and response changes in repeatability cycles of dosimeter also approved the ability of the prepared BeO NPs for use in gamma radiation dosimetry.
Analysis and optimization of mechanical properties of recycled concrete based on aggregate characteristics
Authors: Bian Jiangwei , Zhang Wenbing , Shen Zhenzhong , Li Song , Chen Zhanglan 
Published: September 2021

Abstract
The most significant difference between recycled and natural concretes lies in aggregates. The performance of recycled coarse aggregates directly affects the characteristics of recycled concrete. Therefore, an in-depth study of aggregate characteristics is of great significance for improving the quality of recycled concrete. Based on the coarse aggregate content, maximum aggregate size, and aggregate shape, this study uses experiments, theoretical analysis, and numerical simulation to reveal the impact of aggregate characteristics on the mechanical properties of recycled concrete. In this study, we selected the coarse aggregate content, maximum aggregate size, and the aggregate shape as design variables to establish the regression equations of the peak stress and elastic modulus of recycled concrete using the response surface methodology. The results showed that the peak stress and elastic modulus of recycled concrete reach the best when the coarse aggregate content is 45%, the maximum coarse aggregate size is 16 mm, and the regular round coarse aggregates occupy 75%. Such results provide a theoretical basis for the resource utilization and engineering design of recycled aggregates.
Comment visualiser l’évolution historique des polysémies lexicales : l’itinéraire sémantique de terre et monde
Authors: François Jacques 
Published: September 2021

Abstract
There are two competing approaches to the change of lexical meaning: the individualizing approach, which focuses on the emergence of each particular meaning in a vocable, and the holistic one, which aims to account for the fluctuations, i.e. the expansion, stabilization and contraction of the range of its meanings. The individualizing approach remains dominant until today, although Arsène Darmesteter paved the way for the holistic approach as early as 1887. The purpose of this article is to extract part of the content of the TLF(i)’s historical records in order to build a diachronic semasiological database that can be converted into a series of trees symbolizing the fluctuations of the polysemy of an item century by century. The study is illustrated by exploring the evolutionary polysemy of the verb prévenir and the nouns terre and monde and results in highlighting the period of “coincidence” between the respective polysemies of these two nouns.