bluuebunny/crossref_metadata_2025_split huggingface dataset:
Philosophie, éthique et pensée juive
Authors: Nordmann Sophie 
Published: July 2021

Le séminaire de cette année a été conduit conjointement avec Mme Mazarine Pingeot (université Paris 8) sur le thème « Immanence et transcendance dans la philosophie contemporaine ». Nous avons fait retour sur l’histoire de la philosophie moderne et contemporaine afin d’étudier le tournant immanentiste de la philosophie depuis Kant – notamment chez Schopenhauer, chez Nietzsche et, en prolongement, chez Gilles Deleuze. Le texte d’Emmanuel Levinas intitulé Transcendance et intelligibilité a fait l’objet d’une lecture détaillée.
Protestantismes et culture dans l’Europe moderne(XVIe‑XVIIIe siècle)
Authors: Bost Hubert 
Published: July 2021

L’exercice de mandats électifs successifs (doyen de la section à partir de 2010, président de l’EPHE de 2013 à 2018 et vice‑président recherche et formation graduée de l’université PSL de 2018 à 2020) explique, à défaut d’excuser, le long silence du titulaire de la direction d’études « Protestantismes et culture dans l’Europe moderne, xvie‑xviiie siècle » dans l’Annuaire de la section pendant les années 2011-2019. Cependant, à l’exception de l’année 2017‑2018 qui contraignit de le suspendre en raison des manifestations du cent cinquantenaire de l’École, il a été possible de maintenir le séminaire sous sa forme hebdomadaire. Ce fut parfois avec l’aide de collègues et d’étudiants invités à y intervenir : que soient ici vivement remerciés Chrystel Bernat, Didier Boisson, Céline Borello, Marianne Carbonnier-Burkard, Ana Alicia Carmona Aliaga, Frédéric Gabriel, Xavier Gilly, Jens Häseler, Yves Krumenacker, Francesco Pirocchi, Laura Nicolì, Gianni Paganini, Dominic Schumann et David van der Linden.
« Nouvelle théologie » et redéfinition de la religion en islam contemporain (suite)
Authors: Arminjon Constance 
Published: July 2021

Comme nous l’avions déjà noté l’année dernière, les aspects du renouvellement de la théologie musulmane contemporaine sont apparus avec plus de netteté à mesure que nous étendions notre corpus à des auteurs sunnites égyptiens et turcs et à des auteurs shi’ites non étudiés jusqu’alors. Nous avons étudié les deux principales figures égyptiennes de la « nouvelle théologie » : Nasr Hâmid Abû Zayd (1943‑2010) et Hasan Hanafî (1935‑).
Histoire des courants ésotériques dans l’Europe moderne et contemporaine
Authors: Brach Jean-Pierre 
Published: July 2021

Programme de l’année 2019-2020 : I. La première heure de notre séminaire a été consacrée à la continuation de l’examen d’un manuscrit inédit d’Arcangelo di Borgonovo, consacré à l’interprétation kabbalistique chrétienne du thème des « 50 portes de l’intelligence ». — II. En seconde heure, on a examiné l’influence de l’occultisme contemporain sur la conception de la franc-maçonnerie développée par René Guénon (1886‑1951) dans ses articles de la revue La Gnose (nov. 1909‑fév. 1912).
Pseudorabies Virus DNA Polymerase Processivity Factor UL42 Inhibits Type I IFN Response by Preventing ISGF3-ISRE Interaction
Authors: Zhang Rui , Chen Shifan , Zhang Ying , Wang Mengdong , Qin Chao , Yu Cuilian , Zhang Yunfan , Li Yue , Chen Liankai , Zhang Xinrui , Yuan Xiufang , Tang Jun 
Published: July 2021

Abstract
Alphaherpesviruses are large dsDNA viruses with an ability to establish persistent infection in hosts, which rely partly on their ability to evade host innate immune responses, notably the type I IFN response. However, the relevant molecular mechanisms are not well understood. In this study, we report the UL42 proteins of alphaherpesvirus pseudorabies virus (PRV) and HSV type 1 (HSV1) as a potent antagonist of the IFN-I–induced JAK-STAT signaling pathway. We found that ectopic expression of UL42 in porcine macrophage CRL and human HeLa cells significantly suppresses IFN-α–mediated activation of the IFN-stimulated response element (ISRE), leading to a decreased transcription and expression of IFN-stimulated genes (ISGs). Mechanistically, UL42 directly interacts with ISRE and interferes with ISG factor 3 (ISGF3) from binding to ISRE for efficient gene transcription, and four conserved DNA-binding sites of UL42 are required for this interaction. The substitution of these DNA-binding sites with alanines results in reduced ISRE-binding ability of UL42 and impairs for PRV to evade the IFN response. Knockdown of UL42 in PRV remarkably attenuates the antagonism of virus to IFN in porcine kidney PK15 cells. Our results indicate that the UL42 protein of alphaherpesviruses possesses the ability to suppress IFN-I signaling by preventing the association of ISGF3 and ISRE, thereby contributing to immune evasion. This finding reveals UL42 as a potential antiviral target.
Assessment of serum zinc and copper levels in Egyptian children with β-thalassemia major
Authors: Salama Khaled M. , Kamel Mai H. , El Sayed Safaa M. , Hassanein Samah A. 
Published: July 2021

Background
Thalassemia, with about 60,000 individuals born annually, is a severe inherited anemia, arising from the failure of hemoglobin synthesis.

Objective
This cross-sectional study aimed at evaluating the levels of serum zinc and copper in Egyptian children with β-thalassemia major on two different oral iron chelators, and its relation to clinical and routine laboratory parameters.

Materials and Methods
This cross-sectional study was conducted on sixty Egyptian children, with β-thalassemia major, who were recruited from the Hematology Clinic in New Children Hospital. All of them were below 18 years old. The hemoglobin electrophoresis of each patient was revised as a diagnostic investigation. The patients were classified into two groups: Group I included 30 patients on oral deferasirox, while group II included 30 patients on oral deferiprone. Thirty, age-and-sex-matched children were included in the study as controls. Both cases and controls were subjected to laboratory investigations, which are complete blood count, bilirubin (total and direct), alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, calcium and phosphorous, and zinc and copper levels in serum. Samples were analyzed spectrophotometrically on Beckman AU 680 (Beckman Coulter International, Nyon, Switzerland) using dedicated manufacturer reagents. Serum zinc and copper levels were measured by atomic absorption spectrometry (Perkin Elmer, Buckinghamshire, United Kingdom).

Results
Thirteen percent of the studied cases had low serum zinc level, while none of the control children had low serum zinc level. There was only one case that had high serum zinc level. Thirty five percent of the studied cases had high serum copper level, while none of the controls had high serum copper level, and only one case had low serum copper level. Comparing both types of oral chelators, there was no significant difference in them, regarding the zinc and copper levels.

Conclusions
Serum levels of zinc and copper were significantly altered in the thalassemic cases more than the controls. These levels were not related to the type of oral chelator used or their serum ferritin levels.
Smoking and periodontal disease severity, probing pocket depth and bleeding on probing
Authors: Babu Suresh J , Swarnalatha C , Mathur Ritu , Radhi Alshammari Tayf Naif , Meenakshi Archana , Alavi Asma , Ali Bushara Nashwa Alzaki , Malik Yasser Riaz , Nayyar Abhishek Singh 
Published: July 2021

Background and Objective:
The purpose of the present study was to investigate whether severity of disease process differed between smokers and nonsmokers and to study characteristic differences in pattern of periodontal disease in smokers in a group of known chronic periodontitis patients.

Materials and Methods:
The study included 150 individuals in an age range of 35–60 years wherein periodontal evaluation including probing pocket depth (PPD) and bleeding on probing (BOP) was performed using Williams's periodontal probe. For both the parameters (PPD and BOP), mean scores were calculated from different quadrants of the oral cavity while the results obtained were subjected to statistical analysis.

Results:
The mean percentage of sites that presented with BOP was higher for nonsmokers compared with smokers. Furthermore, smokers had more number of pockets and pockets with increased PPD. On analysis of buccal and lingual sides, also, it was observed that smokers had more number of sites with PPD of ≥5 mm than nonsmokers.

Conclusion:
From the results, it could be concluded that smoking is associated with more severe periodontal attachment and bone loss and deeper periodontal pockets.
Surgically Induced Astigmatism After Phacoemulsification with Clear Corneal 2.75 mm Incision Using Superior Approach
Authors: Amita Angela S. D. , Djunaedi Laura A. , Doniho Angelo , Halim Andrew Adiguna 
Published: July 2021

Context:
Optimal postoperative vision can be achieved through a low surgically induced astigmatism (SIA), which is closely related to the site of incisions. Studies showed that temporal incision gives low SIA. However, a temporal incision is not convenient for some surgeons and in a small operating room with a limited number of assistants. These limitations can be overcome by using a superior approach.

Aims:
The aim of the study was to evaluate SIA after phacoemulsification with clear corneal incision using superior approach in different kinds of astigmatism as an alternative site of incision.

Settings and Design:
Medical records of patients who underwent cataract surgery were collected retrospectively between April and August 2017. Appropriate statistical analyses using Kruskal–Wallis, analysis of variance (ANOVA), Games-Howell test were done to assess the effect of superior approach on corneal curvature and whether it varies between different kinds of astigmatism.

Results:
Kruskal-Wallis test shows that there was no significant postoperative power change across different astigmatism groups (χ
2 (2) = 0.805, P = 0.669). ANOVA and Games-Howell test show that oblique astigmatism had higher changes to its curvature compared with against the rule or with the rule astigmatism.

Conclusions:
The average SIA from the study was 0.34 diopter. Our study concludes that there is no statistically significant difference to SIA between three groups of astigmatism when they were operated using superior approach.
Why Superman Will Not Save the World: Theorizing the Relationship Between Suffering and DC Comics Superman (Translation into Russian)
Authors: Tembo Kwasu 
Published: July 2021

The hypothesis that there is an inextricable link between comic book superheroes and suffering would, to anyone with a cursory knowledge of superhero characters found in DC, Marvel, Image, Wildstorm and other houses, and their histories, ostensibly seem valid. This validity depends on which character one is applying said hypothesis to; the psychological and physical suffering of a Batman being more acceptable as such than that of a Plastic Man, for example. However, using DC Comics character Superman as a case study, this paper explores the inextricable link between Otherness, power, and suffering within the remit of the character's mythos. In order to do so, this paper refers to psychoanalytic concepts elaborated by Sigmund Freud in his text Beyond the Pleasure Principle (1922) as a way of demonstrating that despite the character's conventional appraisal as a positivist humanistic symbol of pure altruism, an insuperable, unimpeachable symbol of selflessness and good morality, there is in fact a fundamental link between Superman's 'tridentity' of selves (Clark Kent/Kal-El/Superman), the character's own suffering, and human suffering on a terrestrial scale, as represented within the numerous realities of the DC Comics Multiverse.
Funciones ejecutivas en infantes con trauma cráneo encefálico moderado-severo
Authors: De León Natareno Elie Alberto , De León López Sandra Concepción , Galindo Cifuentes Julio Cesar , Félix López Omar Alexander 
Published: July 2021

Las funciones ejecutivas son serie de capacidades cognitivas que permiten organizar, modular, controlar, evaluar, regular y planear la conducta. Dentro de su constructo figuran la organización, la atención, memoria de trabajo, la flexibilidad, inhibición, planeación, formulación de metas, autocontrol, anticipación y gestión de tiempos. La neuropsicología estudia los procesos neurocognitivos relacionados con funciones ejecutivas y aplicación en neurorrehabilitación como la terapia cognitivo conductual en trauma craneoencefálico para enfrentar situaciones complejas cuando existe injuria cerebral. Es necesario conocer la relación de las funciones ejecutivas con el trauma craneoencefálico en niños siendo de fuerte interés en los procesos biológicos, neurodesarrollo y factores asociados con el fin de estudiar la neurocognición en relación con las habilidades y contexto en trauma de craneoencefálico. El objetivo de este ensayo es identificar la batería neuropsicológica de las funciones ejecutivas y los lóbulos frontales adaptado al trauma de craneoencefálico en niños para la recuperación pronta mediante un enfoque multidisciplinario. La evaluación neuropsicológica es necesaria para identificar la afección de las funciones ejecutivas que causan discapacidad en trauma de cráneo en niños.
Factores de prevención temprana en enfermedad de Alzheimer
Authors: López Yes Nehemías Feliciano , Moscoso Figueroa Ana Lucia , Monzón Girón María Alejandra , Maldonado Hernández Karen Jackeline , Toledo Jacobo Manuel 
Published: July 2021

La enfermedad de Alzheimer (EA) es una enfermedad neurodegenerativa que se caracteriza en su forma típica por una pérdida de la memoria y progresivamente otras capacidades mentales ejecutivas como la orientación, planificación, generación de nuevos aprendizajes y la resolución de problemas. Es considerada una enfermedad multicausal y compleja siendo la edad el principal factor de riesgo no modificable. Se conoce el origen genético de la EA siendo una demencia neurodegenerativa característica de la población adulta mayor siendo estos pacientes mayores de sesenta años que afecta las funciones cognitivas desarrollando dependencia y fragilidad en este grupo tan vulnerable. Sin embargo, el presente ensayo se enfocará en los factores modificables y preventivos con el objetivo de determinar los factores preventivos de EA contribuir a un diagnóstico precoz y posibilitar intervenciones tempranas. La identificación de los factores de prevención en EA será vitales para realizar cambios modificables del estilo de vida en personas con factores de riesgo neuroepigenéticos con el fin de brindar calidad de vida a quienes sufren esta enfermedad neurodegenerativa.
Cultura Física como proyección de salud, en estudiantes de ECTAFIDE
Authors: Jiménez Enriquez Gabriela Inés 
Published: July 2021

Los estudiantes de la Escuela de Ciencia y Tecnología de la Actividad Física y el Deporte (ECTAFIDE), de la Universidad de San Carlos de Guatemala, estudiaron para adquirir conocimientos teóricos-prácticos que los ayuden a desarrollar habilidades y capacidades físico-deportivas en el ser humano, fomentando la Cultura Física en la sociedad. Fortalecieron las habilidades y aptitudes específicas de la carrera porque utilizan el cuerpo para transmitir, explicar, demostrar y corregir las habilidades-capacidades, en sus diferentes modalidades.
El objetivo fue describir cómo los estudiantes adquirieron y conservaron la cultura física como proyección de salud, siendo los objetivos específicos, identificar qué actividades realizaron los estudiantes para alcanzar el hábito de la actividad física y establecer cómo conservaron la cultura física. Se utilizó el enfoque cuantitativo, descriptivo y se aplicó la encuesta en una muestra de 100 estudiantes de los tres primeros años. Los resultados demostraron que el 93% de los estudiados realizan actividad física, el 80% realiza actividad física tres veces a la semana y diariamente y el 100 % practica actividad física por salud. Concluyendo que los estudiantes, conservan la cultura física y proyectan salud, aplicando lo aprendido en su diario vivir.
Infância e Psicologia: O Brincar é uma Linguagem Secreta?
Authors: Luz Menezes Mable , Silva da Conceição Ana Paula 
Published: July 2021

Este trabalho teve como objetivo discutir a infância através da verificação dos pressupostos da psicologia, para compreender se o brincar é uma linguagem secreta, considerando o processo de desenvolvimento das crianças e a sua relação com o lúdico. O referencial teórico foi com autores como Vygotsky (1998), Piaget (1971), De Quadros (2017), Rolim (2008), Ariès (1981), dentre outros. A opção metodológica foi a pesquisa bibliográfica e documental, com textos acadêmicos e documentos públicos oficiais, construindo uma investigação que dialogou com os vários campos do conhecimento. Logo, os resultados obtidos apresentam que tanto a linguagem como o pensamento estão presentes na relação do brincar da criança quando atingem a capacidade de acesso a função simbólica, como agente de instrumentalizar a ação. A partir do entrecruzamento do pensamento e linguagem provendo novo comportamento, foi desvendado como o brincar está imbrincado na rede simbólica, constituindo-se, também, como uma linguagem secreta na infância.
Optimalisasi Fungsi UPT Raden Soerjo dalam Pengelolaan Tahura Raden Soerjo Berbasis Pemberdayaan Masyarakat
Authors: Asmoro Bramantyo Tri , Tuntu Risang Monne Rangga 
Published: July 2021

Raden Soerjo Community Forest Park (Tahura) is a nature conservation area with a very wide area, so the collaboration between government, in this case UPT Raden Soerjo with the community around the buffer zone or village is needed. This study aims to determine how UPT Raden Soerjo performs the function of empowering the village community in the management of the Raden Soerjo People's Forest Park.. The method used in this research is descriptive analysis and data analysis is done qualitatively. The process of collecting data is done by observation and interview methods. The results of the study are that UPT Raden Soerjo has not yet carried out the maximum role in empowering the buffer village communities. This conclusion was drawn based on indicators in community empowerment, namely inclusion and participation, information channels, local organizational capacity and professionalism of empowering roles and indicators in community participation, namely a forum for the community, direct benefits to the community, fulfillment of community interests, the existence of community control. Keywords : Community, Empowerment, Function, Optimalization
REFLECTION OF THE PROBLEM OF THE DEVELOPMENT OF GENETIC KNOWLEDGE OF STUDENTS IN THE ORGANIZATION OF INDEPENDENT WORK
Authors: Zhunussova R. Zh. , Aidarbayeva D. K. , Sarimbayeva B. B. 
Published: July 2021

Currently, the problem of teaching genetics through students’ independent work is one of the most important areas of higher education. In this article, we offer several methods and techniques for organizing students’ independent work on the subject of genetics in a multilingual education. The methodological improvement course of the biology subject is comprehensively studied from year to year and the results are being published. From this point of view, analyses were conducted on the biology teaching at the university and the independent work of foreign and domestic scientific works in recent years. The article presents the experience of teaching genetics based on the independent work organization of future biology teachers in the conditions of multilingual education at Abai University. The results of experimental studies aimed at testing the effectiveness of independent work have been presented. The analysis of the studies made it possible to conclude that the methodological training of biology students as an object of pedagogical research should include various professional training system aspects. The teaching genetics process in English through independent work encourages students to further in-depth subject and language study.
Choledochal cyst type I-A: a case report
Authors: Cardoso Tiago Magalhães , Brandão Érica Paulinne Pereira , Rodrigues Fernando Fernandes , Ceccato Luíz Felipe Lima 
Published: July 2021

Choledocal cysts are cystic dilations that can occur in a single or multiple form in the biliary tree. Cysts can be congenital or acquired and are associated with numerous anatomical abnormalities. The presence of pain in the upper right quadrant of the abdomen, jaundice and palpable abdominal mass form the classic triad that is present in 15% to 45% of patients. We report the case of a 19-year-old woman patient, who she was admitted with abdominal pain in the right hypochondrium, nausea and vomiting, which evolved into jaundice. When seeking medical care, a large liver cyst and cholelithiasis. Imaging exams revealed liver cyst in segments IV-B,V and VI, lithiasis and biliary polyp.
Peningkatan Hasil Belajar Siswa melalui Model Pembelajaran Problem Based Learning (PBL) pada Mata Pelajaran IPA Kelas IV SDN Blimbing Kabupaten Kediri
Authors: Sulistiana Indra 
Published: July 2021

Penelitian ini disusun dengan tujuan untuk meningkatkan hasil belajar siswa pada mata pelajaran IPA menggunakan model pembelajaran problem based learning pada peserta didik kelas IV SDN Blimbing, Kec. Gurah, Kab.Kediri. Berdasarkan temuan peneliti terkait pembelajaran jarak jauh yang sekarang sedang dijalani di sekolah-sekolah di Indonesia karena pandemi Covid-19 membuat hasil belajar siswa di SDN Blimbing menurun. Hal ini dapat dilihat dari hasil penilaian yang dilakukan oleh guru. Hanya 25% siswa SDN Blimbing Kelas IV yang mampu memenuhi KKM, sedangkan 75% siswa lainnya belum mampu memenuhi KKM yang telah ditentukan. Dengan menggunakan model pembelajaran Problem Based Learning membuat siswa belajar untuk menghadapi masalah pada dunia nyata untuk memulai pembelajaran. Sebelum siswa mempelajari konsep/materi, siswa akan diberikan sebuah masalah yang harus dipecahkan. Oleh karena itu, untuk memecahkan masalah tersebut siswa akan memiliki kesadaran terhadap kebutuhan pengetahuan baru yang harus dipelajari untuk memecahkan masalah yang diberikan. Berdasarkan hasil penelitian yang dilakukan, dapat disimpulkan bahwa dengan menggunakan model pembelajaran Problem Based Learning dapat meningkatkan hasil belajar siswa kelas IV SDN Blimbing Kab. Kediri. Hal ini dapat dilihat dari prosentasi ketuntasan pada siklus I sebesar 60 % meningkat menjadi 85 % pada siklus II. Berdasarkan kesimpulan tersebut, saran yang dapat disampaikan adalah sebaiknya guru mencari metode yang tepat sesuai dengan materi yang akan diajarkan kepada siswa. Guru hendaknya selalu melakukan refleksi setelah melakukan proses pembelajaran.