bluuebunny/crossref_metadata_2025_split huggingface dataset:
Laterally Extended Endopelvic Resection Versus Chemo or Targeted Therapy Alone for Pelvic Sidewall Recurrence of Cervical Cancer
Authors: Park Soo Jin , Mun Jaehee , Lee Seungmee , Luo Yanlin , Chung Hyun Hoon , Kim Jae-Weon , Park Noh Hyun , Song Yong Sang , Kim Hee Seung 
Published: May 2021

BackgroundLaterally extended endopelvic resection (LEER) has been introduced for treatment of pelvic sidewall recurrence of cervical cancer (PSRCC), which occurs in only 8% of patients with relapsed cervical cancer. LEER can only be performed by a proficient surgeon due to the high risk of surgical morbidity and mortality, but there is no evidence as to whether LEER is may be more effective than chemo or targeted therapy alone for PSRCC. Thus, we aimed to compare the efficacy and safety between LEER and chemo or targeted therapy alone for treatment of PSRCC.MethodsWe prospectively recruited patients with PSRCC who underwent LEER between December 2016 and December 2019. Moreover, we retrospectively collected data on patients with PSRCC who received chemo or targeted therapy alone between January 2000 and December 2019. We compared treatment-free interval (TFI), progression-free survival (PFS), treatment-free survival (TFS), overall survival (OS), tumor response, neurologic disturbance of the low extremities, and pelvic pain severity in the different patient groups.ResultsAmong 1295 patients with cervical cancer, we included 28 (2.2%) and 31 (2.4%) in the prospective and retrospective cohorts, respectively. When we subdivided all patients into two groups based on the median value of prior TFI (PTFI, 9.2 months), LEER improved TFI, PFS, TRS and OS compared to chemo or targeted therapy alone (median, 2.8 vs. 0.9; 7.4 vs. 4.1; 30.1 vs. 16.9 months; P ≤ 0.05) in patients with PTFI &lt; 9.2 months despite no difference in survival in those with PTFI ≥ 9.2 months, suggesting that LEER may lead to better TFI, PFS, TRS and OS in patients with PTFI &lt; 9.2 months (adjusted hazard ratios, 0.28, 0.27, 0.44 and 0.37; 95% confidence intervals, 0.12-0.68, 0.11-0.66, 0.18-0.83 and 0.15-0.88). Furthermore, LEER markedly reduced the number of morphine milligram equivalents necessary to reduce pelvic pain when compared with chemo or targeted therapy alone.ConclusionCompared to chemo or targeted therapy alone, LEER improved survival in patients with PSRCC and PTFI &lt; 9.2 months, and it was effective at controlling the pelvic pain associated with PSRCC.Trial RegistrationClinicalTrials.gov, identifier NCT02986568.
Measuring Prospective Imagery: Psychometric Properties of the Chinese Version of the Prospective Imagery Task
Authors: Liu Mingfan , Chen Yiting , Yin Xiaoying , Peng Dandan , Wang Xinqiang , Ye Baojuan 
Published: May 2021

ObjectiveProspective negative imagery is suggested to play an important role in the development and maintenance of anxiety and depression. The Prospective Imagery Task (PIT) was developed to assess prospective imagery. Given the importance of prospective imagery for mental health in the Chinese cultural context, our objective was to examine the psychometric properties of the PIT in a Chinese sample.MethodsThe instrument was validated among a sample of 1,372 Chinese individuals (mean age = 19.98, SD = 4.57; 35.2% male) who completed the PIT immediately following the Beck Depression Inventory-II (BDI-II) and State-Trait Anxiety Inventory-Trait version (STAI-T).ResultsThe two-factor structure of the PIT was in line with the original study, with satisfactory reliability and positive correlations with the BDI-II and STAI-T scores. Latent profile analysis revealed a three-class pattern. The measurement invariance indicated that the instrument can be used among different age groups as well as among males and females.ConclusionThe Chinese version of the PIT is a reliable and valid tool to measure prospective imagery, and the positive subscale is meaningful for clinical psychology. Limitations and future research directions are discussed.
Perception Toward Exposure Risk of COVID-19 Among Health Workers in Vietnam: Status and Correlated Factors
Authors: Le Xuan Thi Thanh , Nguyen Quynh Thi , Onyango Brenda , Nguyen Quang Nhat , Pham Quan Thi , Ta Nhung Thi Kim , Nguyen Thao Thanh , Le Huong Thi , Vu Linh Gia , Hoang Men Thi , Vu Giang Thu , Latkins Carl A. , Ho Roger C. M. , Ho Cyrus S. H. 
Published: May 2021

Background: Hospital staff are at the frontline for the prevention and control of COVID-19. Understanding their perception of exposure risk is, therefore, important during the early phase of this pandemic. In this study, we evaluated the perception regarding risk of exposure to COVID-19 among Vietnamese hospital staff in Vietnam.Method: A cross-sectional online study was carried out to collect demographic data and risk exposure perception during the second week of the national lockdown in April 2020 in Vietnam. Seven hundred and forty two hospital staff were recruited using the snowball sampling to answer 5-point Likert scale questions regarding their risk exposure perception. Exploratory factor analysis (EFA) was used to examine the construct validity of the questionnaire. Pearson coefficient analysis and multivariable regression models were applied to identify factors associated with the perceived COVID-19 exposure risk.Results: Participants perceived a high risk of being infected with SARS-CoV-2 (score = 3.4, SD = 0.8). They also perceived the workplace response to COVID-19 as inadequate (score = 2.0, SD = 0.5). In particular, participants who worked in the emergency or intensive care departments were more likely to perceive an exposure risk, compared to those in infectious disease control departments (Coef. = −0.38, 95%CI: −0.74; −0.02). Participants from central regions perceived a lower risk of exposure to COVID-19 than those from northern regions (OR = 0.52, 95%CI: 0.28–0.96). Nurses were less likely than doctors to report being at risk of exposure to COVID-19 (OR = 0.56, 95%CI: 0.33–0.95).Conclusions: We identified a high level of perceived risk regarding COVID-19 exposure among hospital staff during the unprecedented lockdown period in Vietnam. A comprehensive approach, incorporating improved risk communications, safety training and psychological support programs, for all hospital staff, including nurses and those residing in high population density areas, might further strengthen the national effort to control the pandemic.
Autonomous Robotic Point-of-Care Ultrasound Imaging for Monitoring of COVID-19–Induced Pulmonary Diseases
Authors: Al-Zogbi Lidia , Singh Vivek , Teixeira Brian , Ahuja Avani , Bagherzadeh Pooyan Sahbaee , Kapoor Ankur , Saeidi Hamed , Fleiter Thorsten , Krieger Axel 
Published: May 2021

The COVID-19 pandemic has emerged as a serious global health crisis, with the predominant morbidity and mortality linked to pulmonary involvement. Point-of-Care ultrasound (POCUS) scanning, becoming one of the primary determinative methods for its diagnosis and staging, requires, however, close contact of healthcare workers with patients, therefore increasing the risk of infection. This work thus proposes an autonomous robotic solution that enables POCUS scanning of COVID-19 patients’ lungs for diagnosis and staging. An algorithm was developed for approximating the optimal position of an ultrasound probe on a patient from prior CT scans to reach predefined lung infiltrates. In the absence of prior CT scans, a deep learning method was developed for predicting 3D landmark positions of a human ribcage given a torso surface model. The landmarks, combined with the surface model, are subsequently used for estimating optimal ultrasound probe position on the patient for imaging infiltrates. These algorithms, combined with a force–displacement profile collection methodology, enabled the system to successfully image all points of interest in a simulated experimental setup with an average accuracy of 20.6 ± 14.7 mm using prior CT scans, and 19.8 ± 16.9 mm using only ribcage landmark estimation. A study on a full torso ultrasound phantom showed that autonomously acquired ultrasound images were 100% interpretable when using force feedback with prior CT and 88% with landmark estimation, compared to 75 and 58% without force feedback, respectively. This demonstrates the preliminary feasibility of the system, and its potential for offering a solution to help mitigate the spread of COVID-19 in vulnerable environments.
Predicting Multi-Epitope Peptide Cancer Vaccine from Novel TAA Topo48
Authors: Setiawan Tirta , Rizarullah Rizarullah 
Published: May 2021

Cancer is one of the most lethal diseases. Recently, cancer immunotherapy has a tremendous achievement in cancer treatment. A certain number of cancer based epitope vaccines with different moiety have been discovered. In japan, several clinical tests of cancer based epitope vaccine derived from tumor associated antigens (TAAs) are now ongoing or have recently been completed. a novel of TAAs potentially as cancer vaccine have been retrieved from a fragment weighed 48kDa derived from human DNA-topoisomerase 1 (TOP1) called Topo48. Therefore, it is still critical to discover a derived Topo48 epitope based cancer vaccine. Immuno-informatics considered as a methods noted to have better accuracy to design promising vaccine candidates. Here, continuous and discontinuous B-cell epitopes following with CTL epitopes and their docking interaction to major histocompatibility complex (MHC) class I Human Leukocyte Antigens (HLA)- A0201 were predicted. Kolaskar-Tongaonkar’s, Emini’s, Karpus-Schulz’s, and Parker’s methods were used to predict continuous B-cell epitopes while ElliPro was used for prediction of discontinued B-cell epitopes. Those considered methods marked to have better accuracy to design promising vaccine candidates. Similarly, CTL epitopes was also predicted by using NetCTL server and the best candidates were further investigated their binding affinity by mean of PEP-FOLD3, PatchDock rigid-body docking server, and FireDock server. Total 27 continuous epitopes and 7 discontinuous B-cell epitopes were predicted. In the other hand, 9 peptides were predicted as CTL epitopes. Whereas, three predicted CTL epitope in range 263MLDHEYTTK27, 755AIDMADEDY763, 715ALGTSKLNY724) exhibited good interactions to HLA-A0201. Moreover, we also found residues His266, Thr270, Ala755, Tyr723, Thr718, Ser719, Lys720 from Topo48 and residues Thr163, Asp757, His70, Glu63 from HLA- A0201 were indicated to be antigenic. Ultimately, our proposed continuous/discontinuous B-cell epitopes, and also CTL epitopes can be potential vaccines for cancer immunotherapy.
Karakterisasi Fisik, Kimia, dan Sensoris Saus Sambal Mangga Kweni (Mangifera odorata Griff) dengan Variasi Konsentrasi Asam Sitrat dan Durasi Sterilisasi
Authors: Fitriani Vita , Ayuningtyas Hesti , Mareta Dea Tio , Permana Lasuardi , Wahyuningtyas Amalia 
Published: May 2021

Mangga kweni (Mangifera odorata Griff) merupakan salah satu jenis mangga yang cukup banyak dibudidayakan oleh masyarakat dan banyak dimafaatkan dalam pembuatan sambal, khususnya di daerah Lampung dan Palembang. penelitian ini bertujuan untuk mengembangkan produk saus sambal kweni instan dengan penambahan asam sitrat dan perlakuan sterilisasi. Variasi konsentrasi asam sitrat dalam penelitian ini adalah 0%, 0,1%, 0,3%, dan 0,5%, dengan durasi sterilisasi 20 menit dan 35 menit. Pengujian yang dilakukan terhadap saus sambal kweni berupa analisis sifat fisik, kimia, dan sensoris. Hasil penelitian menunjukkan bahwa variasi pemberian asam sitrat dan lama sterilisasi berpengaruh signifikan (p<0,05) terhadap kadar air, nilai pH, viskositas dan warna. hasil analisis sensoris berdasar uji tingkat kesukaan (hedonik), menunjukkan tidak ada perbedaan yang signifikan antar sampel, namun secara keseluruhan atribut (overall), sampel D yang disterilisasi 35 menit adalah yang paling disukai panelis.
Kesiapan Adaptasi Kebiasaan Baru Pencegahan Penularan Covid 19
Authors: Nugroho Sri Hananto Ponco , Umma Nahdliyah , Lianawati Novi , Pornomo Hery , Kusumawati Gigih Rahayu , Kusumawati Gigih Rahayu 
Published: May 2021

Saat ini bangsa Indonesia sedang menghadapi tantangan yang mengharuskan sumber daya manusia beradaptasi dengan situasi pandemi Corona Virus Disease 2019 (Covid-19). Prinsip pencegahan penularan Covid-19 pada individu dilakukan dengan menghindari masuknya virus antara lain menggunakan masker, mencuci tangan, menjaga jarak dan meningkatkan daya tahan tubuh. Akan tetapi penerapan protokol kesehatan pada masyarakat belum dilaksanakan dengan optimal. Tujuan pengabdian masyarakat ini adalah untuk meningkatkan pelaksanaan protokol kesehatan pada adaptasi kebiasaan baru. Kegiatan dilakukan melalui penyuluhan kesiapan adaptasi kebiasaan baru, pelatihan cuci tangan dan membuat hand sanitizer, pelatihan pemanfaatan tanaman obat keluarga (TOGA) dan pelatihan pembuatan tanaman TOGA. Metode yang dipakai yaitu sosialisasi, penyuluhan, pelatihan dan pendampingan. Hasil dari kegiatan pengabdian yaitu tercapainya kegiatan sosialisasi, penyuluhan, pelatihan dan pendampingan dengan baik, dan secara umum masyarakat dapat melakukan adaptasi kebiasaan baru dengan baik.
PKM Kader Posyandu Juru Batuk Tuberculosis di Desa Allang Kecamatan Leihitu Barat Kabupaten Maluku Tengah, Maluku
Authors: Lawalata Ivy Violan , Mamuly Wilma Fransisca , Maelissa Ns Sinthia , Pantouw Felix Falentino , Irfan Cahya Vanti 
Published: May 2021

Provinsi Maluku jumlah kasus 3.202 dan Case Notification Rate 184 kasus dan BTA (+) 78. Puskesmas Allang tahun 2018 jumlah kasus TB sebanyak 8 orang Kasus TB adak Sebanyak 1 orang, Kasus Drop out sebanyak 1 orang dan kasus esxtra paru sebanyak 2 orang. Kegiatan Pengabdian masyarakat dilakukan pada kader posyandu di Desa Allang Kecamatan Leihitu Barat Kabupaten Maluku Tengah, dilakukan berdasarkan permasalahan pada masyarakat yang memiliki kesadaran dan pengetahuan yang rendah yang berdampak pada penularan tuberculosis didalam keluarga, tidak ke pusat pelayanan kesehatan untuk memperoleh pengobatan, kader posyandu desa allang dijadikan sebagai kelompok mitra dalam pengabdian kepada masyarakat hal ini dikarenakan kader posyandu cukup berperan dalam kegiatan pelayanan kesehatan di puskesmas serta kader juga merupakan tokoh yang berperan dalam pemberdayaan masyarakat sehingga kader diberikan materi untuk meningkatakan pengetahuan tentang tuberculosis sehingga dapat mentransfer kepada masyarakat serta kader dilatih dan dalam menemukan penderita tuberculosis dalam keluarga serta mengantar ke puskesmas untuk melakukan pengobatan.Tujuan dari kegiatan pengabdian ini adalah ; Membantu meningkatakan pengetahuan kader posyandu serta memberikan pelatihan serta praktek bersama kader posyandu Juru Batuk Tuberculosis untuk menemukan anggota keluarga orang yang dicurigai menderita TB. Untuk dapat memecahkan masalah mitra agar dapat memahami tentang upaya pengendalian penyakit tuberculosis didalam keluarga maupun masyarakat. Maka Tim melakukan Kegiatan Pengabdian terhadap 20 orang kader posyandu di Desa Allang Kecamatan Leihitu Barat Kabupaten Maluku Tengah untuk di latih sebagai Juru Batuk Tuberculosis dalam kegiatan ini beberapa kegiatan telah di implemntasikan yaitu Brosur dan Buku Saku tentang TB ssebagai luaran tambahan telah diberikan bagi kader dalam kegaiatn pelatihan , materi pelatihan telah disampaikan oleh narasumberdari dinas kesehatan provinsi Maluku hasil yang diperoleh adanya peningkatan pengatahuan kader sebelum dan sesudah meningkat sebesar 34%, praktek bersama terhadap penderita TB di fasilitasi oleh pemegang program TB puskesmas perawatan Allang. Luaran kegiatan pengabdian kepada masayarkat ini telah di publikasi melalui media massa https://www.malukunews.co/berita/kiriman-pengunjung/fcw6y4c0rkb6I/kader-allang-sebagai-juru-batuk-tuberculosis-jumantuk serta video kegiatan telah di upload pada chanel youtobe https://youtobe.be/SYnW_1xon90. UKIM
INTRODUCTION IN THE FAR EAST: PROBLEMS AND PROSPECTS
Authors: Урусов В.М. , Варченко Л.И. 
Published: May 2021

Интродукция лесообразователей на Дальнем Востоке начинается с 1805 г. во владениях Российско-Американской компании, становится масштабной после 1890 г. в Хабаровске, Владивостоке, Уссурийске, Шмаковском монастыре, после 1930 г. – на юге Сахалина. Используются ели европейская, сибирская, колючая и лиственницы японская и Гмелина, сосны Банкса, веймутова, обыкновенная, сибирская, робиния, ясень пенсильванский. Массовое введение интродуцентов начинается после 1936 г. (создана Горнотаёжная станция) и после 1948 г. (организация академического Ботанического сада). Хорошие результаты таёжных пород Европы и Америки получены на Сахалине и отчасти в Приморье. Наиболее перспективен метод подбора интродуцентов по сходству климатов – климатических аналогов.
The introduction of forest-forming species in the Far East begins in 1805 in the possession of the Russian-American company, becomes large-scale after 1890 in Khabarovsk, Vladivostok, Ussuriisk, Shmakovsky monastery, after 1930 - in the south of Sakhalin. Are used Picea abies, P. obovata, P. pungens; Larix leptolepis and L. dahurica; Pinus banksiana, P. strobus, P. sylvestris, P. sibirica; Robinia, Fraxinus pennsylvanica. The massive use of the introductions species begins after 1936 (the Gornotezhnaya Station was established) and after 1948 (the organization of the Academic Botanical Garden). Good results for the taiga breeds of Europe and America were obtained on Sakhalin and partly in Primorye. The most promising method for the selection of introduced species by the similarity of climates - of the climatic analogues.
Implementasi Program Keluarga Harapan (PKH) di Kecamatan Gayungan Surabaya Pada Era Adaptasi Kebiasaan Baru
Authors: Chasanah Uswatun , Novitasari Tharisma , Nabila Aisya Safira , Wahyudi Kalvin Edo 
Published: May 2021

PKH merupakan program pemberian bantuan sosial bersyarat kepada keluarga dan / seseorang miskin atau rentan yang terdaftar dalam data terpadu program penanganan fakir miskin, diolah oleh pusat data dan informasi kesejahteraan sosial dan ditetapkan sebagai keluarga penerima manfaat. Namun dalam penyaluran Program Keluarga Harapan di Kecamatan Gayungan ditemukan fenomena pemberitaan dari media dimana ditemukan penarikan dana sejumlah Rp. 25.000,- kepada Keluarga Penerima Manfaat yang telah dianggap masyarakat sebagai pungutan liar. Tujuan dari penelitian ini mengetahui implementasi Program Keluarga Harapan di kecamatan Gayungan Surabaya pada era adaptasi kebiasaan baru. Penelitian ini berdasarkan teori George C. Edward III sebagai tolak ukur implementasi Program Keluarga Harapan dikecamatan Gayungan. Penelitian ini dilakukan pada Kecamatan Gayungan Kota Surabaya menggunakan metode kualitatif. Teknik pengumpulan data yang digunakan yaitu, wawancara, observasi, dan dokumentasi dengan maksud ingin memperoleh gambaran yang komprehensif dan mendalam tentang Implementasi Program Keluarga Harapan di Kecamatan Gayungan Kota Surabaya. Hasil penelitian ini diharapkan dapat mengetahui perbedaan penyaluran Program Keluarga Harapan di Kecamatan Gayungan Kota Surabaya sebelum pandemic dan semasa Adaptasi Kebiasaan Baru. Hasil penelitian menunjukkan bahwa implementasi PKH berdasarkan teori George C. Edward III yaitu komunikasi,sumberdaya,disposisi dan struktur birokrasi dalam Implementasi Kebijakan PKH sudah berhasil karena dapat menurunkan angka kemiskinan yang ada di Indonesia, lalu untuk implementasi PKH di Adaptasi Kebiasaam Baru (AKB) terdapat beberapa perubahan dari komunikasi yang melakukan sosialisasi dengan via Zoom dan Koordinator kecamatan untuk mengurangi adanya kerumunan, namun hal ini dirasa kurang efektif dan efisien, sehingga Koordinator Program Keluarga Harapan (PKH) mengubah strategi dengan cara membagi zona.
PENINGKATAN MANAJEMEN KINERJA MELALUI TOTAL KUALITAS MANAJEMEN, SISTEM PENGUKURAN KINERJA DAN SISTEM PENGHARGAAN DI BALAI BESAR LOGAM DAN MESIN
Authors: Ramathina Fifi Ainur , Indriani Dewi 
Published: May 2021

Abstrak - Balai Besar Logam dan Mesin merupakan balai yang berdiri berdasarkan SK direktorat Jendral Perindustrian Dasar No.48/Kpts.DD/Perdas. Dalam hal ini penulis bertujuan untuk meneliti tentang manajemen kinerja, total kualitas manajemen, sistem pengukuran kinerja serta sistem penghargaan. Lokasi penelitian ini dilakukan pada Balai Besar Logam dan Mesin. Riset ini termasuk ke dalam jenis kuantitatif dengan mengacu pada wawancara serta kuesioner. dengan menggunakan metode sampel yang terdiri dari 53 responden. penelitian ini ditunjukkan bagi pegawai PNS. Teknik pengumpulan data menggunakan kuesioner untuk menilai seberapa tinggi peningkatan manajemen kinerja. Hasil riset ini menunjukkan bahwa semua pertanyaan yang diajukan bersifat valid dan reliabel. Uji deskriptif menghasilkan bahwa keempat variabel tergolong baik, sedangkan pada uji verifikatif menghasilkan ketiga variabel secara bersamaan memiliki pengaruh yang signifikan terhadap manajemen kinerja.
Abstract - Balai Besar Logam dan Mesin is a hall that is eshtablished based on the Decree of Directorate General of Basic Industry No.48/Kpts.DD/Perdas. This study is purpose for detect improving management performance through totaI quality management, system measurement performance and reward system. The location research at Balai Besar Logam dan Mesin. The reaserch belongs to the type of quantitative detailed with reference to interview and questionnaire. The method use is a sample, which consists 53 respondents. The subjects in this study were servants at Balai Besar Logam dan Mesin. The data gathering technique method is questionnaire is used to assess how high improvement management performance. Study result indicate that all character question are valid and reliable. Descriptive analysis show are four variables precious good. Verification analysis show the together variable independent have a significant effect on variable dependen.
Pengaruh Jenis Larutan Pemasak Terhadap Kualitas Pulp Daun Pisang
Authors: Listyarini Risnita Vicky , Dewi Noer Kurnia 
Published: May 2021

The need for paper continues to increase, indicating that there is an alternative wood material that can be used as a base for making pulp. Materials that can be used are dried banana leaves which contain cellulose. The quality of the pulp can be obtained by the characteristics of the pulp produced. This study was conducted to determine the effect of the type of solvents on the pulp quality of banana leaves. The pulp has been made using delignification process with addition of 3% NaOH or 3% Na2CO3 3% and heating up to 120 minutes, at 105 °C. Pulp quality was obtained from the results of pulp analysis, cellulose content, water content, physical appearances and qualitative analysis by FTIR. From the analysis of cellulose content, water content and FTIR instruments, pulp made with 3% NaOH solution are better suited to 3% Na2CO3 where the resulting pulp has a water content of 4.96%, a smooth and fibrous texture, a rich color, and produces a cellulose hydroxyl absorption band that is stronger than the pulp made of 3% Na2CO3. However, the pulp made from 3% NaOH solution has a lower yield (56.5%) and cellulose content (26.07%) than Na2CO3 3%. Dried banana leaves can be used as an alternative in pulp making.

Keywords: pulp making; banana leaves; solvents