bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dirac masses and mixings in the (geo)SM(EFT) and beyond
Authors: Talbert Jim , Trott Michael 
Published: November 2021

Abstract
We report a set of exact formulae for computing Dirac masses, mixings, and CP-violation parameter(s) from 3×3 Yukawa matrices Y valid when YY† → U†YY†U under global $$ \mathrm{U}{(3)}_{Q_L} $$
U

3

Q
L

flavour symmetry transformations U. The results apply to the Standard Model Effective Field Theory (SMEFT) and its ‘geometric’ realization (geoSMEFT). We thereby complete, in the Dirac flavour sector, the catalogue of geoSMEFT parameters derived at all orders in the $$ \sqrt{2\left\langle {H}^{\dagger }H\right\rangle } $$

2

H
†

H

/Λ expansion. The formalism is basis-independent, and can be applied to models with decoupled ultraviolet flavour dynamics, as well as to models whose infrared dynamics are not minimally flavour violating. We highlight these points with explicit examples and, as a further demonstration of the formalism’s utility, we derive expressions for the renormalization group flow of quark masses, mixings, and CP-violation at all mass dimension and perturbative loop orders in the (geo)SM(EFT) and beyond.
Nucleotide excision repair leaves a mark on chromatin: DNA damage detection in nucleosomes
Authors: Apelt Katja , Lans Hannes , Schärer Orlando D. , Luijsterburg Martijn S. 
Published: November 2021

AbstractGlobal genome nucleotide excision repair (GG-NER) eliminates a broad spectrum of DNA lesions from genomic DNA. Genomic DNA is tightly wrapped around histones creating a barrier for DNA repair proteins to access DNA lesions buried in nucleosomal DNA. The DNA-damage sensors XPC and DDB2 recognize DNA lesions in nucleosomal DNA and initiate repair. The emerging view is that a tight interplay between XPC and DDB2 is regulated by post-translational modifications on the damage sensors themselves as well as on chromatin containing DNA lesions. The choreography between XPC and DDB2, their interconnection with post-translational modifications such as ubiquitylation, SUMOylation, methylation, poly(ADP-ribos)ylation, acetylation, and the functional links with chromatin remodelling activities regulate not only the initial recognition of DNA lesions in nucleosomes, but also the downstream recruitment and necessary displacement of GG-NER factors as repair progresses. In this review, we highlight how nucleotide excision repair leaves a mark on chromatin to enable DNA damage detection in nucleosomes.
Anstieg depressiver Symptome bei Jugendlichen und jungen Erwachsenen während des ersten Lockdowns in Deutschland
Authors: Naumann Elias , von den Driesch Ellen , Schumann Almut , Thönnissen Carolin 
Published: November 2021

Zusammenfassung
Hintergrund
Die COVID-19-Pandemie (Corona Virus Disease 2019) hat innerhalb kürzester Zeit das gesellschaftliche Leben grundlegend verändert. Bei politischen Entscheidungen steht oft die Abwägung zwischen der Pandemiebekämpfung und den möglichen negativen wirtschaftlichen Konsequenzen im Vordergrund. Zunehmend finden jedoch auch die psychologischen und sozialen Auswirkungen des Lockdowns Beachtung.

Fragestellung
Wie hat sich die psychische Gesundheit von Jugendlichen und jungen Erwachsenen in Deutschland während der ersten Welle der COVID-19-Pandemie und der dadurch bedingten Kontaktbeschränkungen in Deutschland verändert?

Material und Methoden
Die Analysen basieren auf Längsschnittdaten von bundesweit per Zufallsverfahren ausgewählten Ankerpersonen des Beziehungs- und Familienpanels pairfam. Die hier betrachtete Altersgruppe der Geburtsjahrgänge 2001–2003 wurde im Jahr 2018/2019 erstmalig im Zuge einer Aufstockungsstichprobe befragt und 854 dieser Jugendlichen und jungen Erwachsenen im Alter von 16–19 Jahren nahmen auch an der COVID-19-Zusatzbefragung von Mai bis Juli 2020 (erster Lockdown) teil. Die Depressivität wird mit der State-Trait Depression Scale erhoben.

Ergebnisse
Während des ersten Lockdowns zeigte sich bei den jungen Menschen ein deutlicher Anstieg depressiver Symptome: Vor dem Lockdown hatten 10,4 % klinisch relevante depressive Symptome [95 %-KI: 8,4; 12,5], im Frühjahr 2020 stieg dieser Anteil auf 25,3 % [95 %-KI: 22,4; 28,2]. Das Risiko, depressive Symptome zu entwickeln, war bei weiblichen Jugendlichen und jungen Frauen erhöht. Der Migrationshintergrund zeigte sich als ein ähnlich starker Risikofaktor: Die Prävalenz depressiver Symptome stieg bei Migrationshintergrund von 11 % auf 33 %.

Diskussion
Um diese Risikogruppen zu erreichen, sind flächendeckende, zielgruppenspezifische und niedrigschwellige Angebote der Prävention und Gesundheitsförderung nötig.
Walrasian equilibrium theory with and without free-disposal: theorems and counterexamples in an infinite-agent context
Authors: Anderson Robert M. , Duanmu Haosui , Khan M. Ali , Uyanik Metin 
Published: November 2021

AbstractThis paper provides four theorems on the existence of a free-disposal equilibrium in a Walrasian economy: the first with an arbitrary set of agents with compact consumption sets, the next highlighting the trade-offs involved in the relaxation of the compactness assumption, and the last two with a countable set of agents endowed with a weighting structure. The results generalize theorems in the antecedent literature pioneered by Shafer–Sonnenschein in 1975, and currently in the form taken in He–Yannelis 2016. The paper also provides counterexamples to the existence of non-free-disposal equilibrium in cases of both a countable set of agents and an atomless measure space of agents. One of the examples is related to one Chiaki Hara presented in 2005. The examples are of interest because they satisfy all the hypotheses of Shafer’s 1976 result on the existence of a non-free-disposal equilibrium, except for the assumption of a finite set of agents. The work builds on recent work of the authors on abstract economies, and contributes to the ongoing discussion on the modelling of “large” societies.
Stent Graft Placement by Pseudoaneurysm of the Hepatic Arteries: Efficacy and Patency Rate in Follow-up
Authors: Pedersoli F. , Van den Bosch V. , Sieben P. , Barzakova E. , Schulze-Hagen M. , Isfort P. , Keil S. , Wiltberger G. , Kuhl C. K. , Bruners P. 
Published: November 2021

Abstract
Purpose
To investigate efficacy and patency status of stent graft implantation in the treatment of hepatic artery pseudoaneurysm.

Materials and Methods
A retrospective analysis of patients who had undergone endovascular treatment of hepatic artery pseudoaneurysms between 2011 and 2020 was performed. Medical records were examined to obtain patients’ surgical histories and to screen for active bleeding. Angiographic data on vascular access, target vessel, material used and technical success, defined as the exclusion of the pseudoaneurysm by means of a stent graft with sufficient control of bleeding, were collected. Vessel patency at follow-up CT was analyzed and classified as short-term (< 6 weeks), mid-term (between 6 weeks and 1 year), and long-term patency (> 1 year). In case of stent occlusion, collateralization and signs of hepatic hypoperfusion were examined.

Results
In total, 30 patients were included and of these, 25 and 5 had undergone stent graft implantation and coiling, respectively. In patients with implanted stent grafts, technical success was achieved in 23/25 patients (92%). Follow-up CT scans were available in 16 patients, showing stent graft patency in 9/16 patients (56%). Short-term, mid-term, and long-term short-term stent patency was found in 81% (13/16), 40% (4/10), and 50% (2/4). In patients with stent graft occlusion, 86% (6/7) exhibited maintenance of arterial liver perfusion via collaterals and 14% (1/7) exhibited liver abscess during follow-up.

Conclusion
Stent graft provides an effective treatment for hepatic artery pseudoaneurysms. Even though patency rates decreased as a function of time, stent occlusion was mainly asymptomatic due to sufficient collateralization.
A beacon of dung: using lemming (Lemmus lemmus) winter nests and DNA analysis of faeces to further understand predator–prey dynamics in Northern Sweden
Authors: Vigués Jan , Menci Silvia , Wilkinson Caitlin , Le Vaillant Maryline , Angerbjörn Anders , Norén Karin 
Published: November 2021

Abstract The hypothesis that predation is the cause of the regular small rodent population oscillations observed in boreal and Arctic regions has long been debated. Within this hypothesis, it is proposed that the most likely predators to cause these destabilizing effects are sedentary specialists, with small mustelids being possible candidates. One such case would be the highly specialized least weasel (Mustela nivalis) driving the Norwegian lemming (Lemmus lemmus) cycle in Fennoscandia. These predators are often elusive and therefore distribution data can only be based on field signs, which is problematic when various mustelid species are sympatric, such as weasels and stoats (Mustela erminea). Here we present the results of using mustelid faeces in predated winter lemming nests to correctly identify the predator and thus discern which species exerts the strongest predation pressure on lemming winter populations. Samples were obtained during different phases in the lemming cycle, spanning 6 years, to account for different prey densities. Faecal mitochondrial DNA extraction and amplification of a 400-bp fragment was successful in 92/114 samples (81%); the sequencing of these samples proved that most predation occurrences (83%) could be attributed to the least weasel. These findings support the hypothesis that weasels in particular show high specificity in predation and could therefore be candidates to driving the lemming cycle in this area. We conclude that DNA analysis of faecal remains around predated nests can be a useful tool for further investigations concerning predator–prey interactions in the tundra.
Attribution of the seasonality of atmospheric heating changes over the western tropical Pacific with a focus on the spring season
Authors: Lin Shuheng , Yang Song , He Shan , Li Zhenning , Chen Jiaxin , Dong Wenjie , Wu Jiaxue 
Published: November 2021

AbstractAtmospheric diabatic heating, a major driving force of atmospheric circulation over the tropics, is strongly confined to the tropical western North Pacific (TWNP) region, with the global warmest sea surface temperature (SST). The changes in diabatic heating over the TWNP, which exert great impacts on the global climate system, have recently exhibited a noticeable seasonal dependence with a remarkable increase in boreal spring. In this study, we applied observations, reanalysis data, and numerical experiments to investigate the causes of the seasonality in heating changes. Results show that in boreal spring convection is more sensitive to the TWNP SST, leading to a more significant enhancement of deep convection, although the increase in the SST is nearly the same as that in the other seasons. In the non-spring seasons, the enhanced convection due to increased local SST is suppressed by the anomalous anticyclonic wind shear over the TWNP, generated by the easterly wind anomalies induced by the tropical Indian Ocean (TIO) warming via the Kevin waves. However, the TIO warming does not show any suppressing effect in spring because it is much weaker than that in the other seasons and thus the warming itself cannot induce sufficient convective heating anomalies to excite the Kelvin waves.
The impact of nutritional risk factors and sarcopenia on survival in patients treated with pelvic exenteration for recurrent gynaecological malignancy: a retrospective cohort study
Authors: Seebacher Veronika , Rockall Andrea , Nobbenhuis Marielle , Sohaib S. Aslam , Knogler Thomas , Alvarez Rosa M. , Kolomainen Desiree , Shepherd John H. , Shaw Clare , Barton Desmond P. 
Published: November 2021

Abstract
Purpose
The aim of the present study is to investigate the prognostic significance of nutritional risk factors and sarcopenia on the outcome of patients with recurrent gynaecological malignancies treated by pelvic exenteration.

Methods
We retrospectively evaluated muscle body composite measurements based on pre-operative CT scans, nutritional risk factors as assessed by a validated pre-operative questionnaire, and clinical–pathological parameters in 65 consecutive patients with recurrent gynaecological malignancies, excluding ovarian cancer, treated by pelvic exenteration at the Royal Marsden Hospital London. Predictive value for postoperative morbidity was investigated by logistic regression analyses. Relevant parameters were included in uni- and multivariate survival analyses.

Results
We found only (1) low muscle attenuation (MA)—an established factor for muscle depletion—and (2) moderate risk for malnutrition to be independently associated with shorter overall survival (p = 0.006 and p = 0.008, respectively). MA was significantly lower in overweight and obese patients (p = 0.04). Muscle body composite measurements were not predictive for post-operative morbidity.

Conclusion
The study suggests that pre-operative low MA and moderate risk for malnutrition are associated with shorter survival in patients with recurrent gynaecological malignancies treated with pelvic exenteration. Further studies are needed to validate these findings in larger cohorts.
Papillary lesions of the breast
Authors: Kulka Janina , Madaras Lilla , Floris Giuseppe , Lax Sigurd F. 
Published: November 2021

AbstractPapillary lesions of the breast represent a heterogeneous group of lesions including benign papillomas, papillomas with focal epithelial atypia, fully fledged ductal carcinoma in situ (DCIS) or lobular neoplasia, papillary DCIS, encapsulated papillary carcinomas without or with invasion, solid papillary carcinomas, and invasive papillary carcinomas. A micropapillary pattern characterized by lack of fibrous stalks within the papillae is observed in micropapillary DCIS and invasive micropapillary carcinoma. In addition, a variety of other rare breast lesions reveals a papillary architecture such as tall cell carcinoma with reversed polarity (TCCRP) and mucinous cystadenocarcinoma, adenomyoepithelioma, and secretory carcinoma. In addition, benign lesions such as usual ductal hyperplasia, apocrine metaplasia, gynecomastia, and juvenile papillomatosis may show a papillary or micropapillary architecture. Fragments of a benign papilloma in a breast biopsy are considered a lesion of uncertain malignant potential (B3 in the European classification) and excision is mostly recommended. Although the knowledge about molecular pathology of papillary breast lesions has increased, there is not sufficient evidence for diagnostically useful molecular features, yet. The aim of this review is to provide an update on papillary and micropapillary lesions with emphasis on problematic areas for daily diagnostic work including biopsies.
Comparative analysis of postoperative pain after transvaginal hybrid NOTES versus traditional laparoscopic cholecystectomy in obese patients
Authors: Bulian Dirk R. , Walper Sebastian , Richards Dana C. , Schulz Sissy-A. , Seefeldt Claudia S. , Thomaidis Panagiotis , Meyer-Zillekens Jurgen , Heiss Markus M. 
Published: November 2021

Abstract
Purpose
Even though obesity is a known risk factor for needing cholecystectomy, most research excludes patients with higher degrees of obesity. The aim of this retrospective study was to compare postoperative pain and analgesic consumption in obese patients, who underwent either transvaginal hybrid Natural Orifice Transluminal Endoscopic Surgery (NOTES) cholecystectomy (NC) or traditional laparoscopic cholecystectomy (LC).

Methods
Between 12/2008 and 01/2017, 237 NC were performed, of which 35 (14.8%) showed a body mass index (BMI) of 35 kg/m2 or more (obesity II and III according to the World Health Organization). Of these, procedural time, postoperative pain, analgesic requirements, and other early postoperative parameters were collected and compared with 35 matched LC patients from the same time period.

Results
There were no differences in the baseline characteristics between the two groups, but we found significant benefits for the hybrid NOTES technique in terms of less pain (P = 0.006), coherent with significantly less intake of peripheral (paracetamol; P = 0.005), and of centrally acting analgesics (piritramide; P = 0.047) within the first two-day post-surgery. We also found that those in the NC group had shorter hospital stays (P < 0.001). The postoperative complication rates and the procedural time did not differ between the two groups.

Conclusion
With regard to postoperative pain and analgesic requirements and without an increase in postoperative complications, obese patients experience short-term benefits from the hybrid NOTES technique compared to traditional laparoscopic cholecystectomy.
Modeling of COVID-19 propagation with compartment models
Authors: Bärwolff Günter 
Published: November 2021

AbstractThe current pandemic is a great challenge for several research areas. In addition to virology research, mathematical models and simulations can be a valuable contribution to the understanding of the dynamics of the pandemic and can give recommendations to both physicians and politicians. In this paper we give an overview about mathematical models to describe the pandemic by differential equations. As a matter of principle the historic origin of the epidemic growth models will be remembered. Moreover we discuss models for the actual pandemic of 2020/2021. This will be done based on actual data of people infected with COVID-19 from the European Centre for Disease Prevention and Control (ECDC), input parameters of mathematical models will be determined and applied. These parameters will be estimated for the UK, Italy, Spain, and Germany and used in a SIR-type model. As a basis for the model’s calibration, the initial exponential growth phase of the COVID-19 pandemic in the named countries is used. Strategies for the commencing and ending of social and economic shutdown measures are discussed. To respect heterogeneity of the people density in the different federal states of Germany diffusion effects are considered.
The Association of Distinct Social Determinants of Health with Added Sweetener Knowledge and Consumption in a U.S. Sample of People Living with HIV
Authors: Kileel Emma M. , Dickins Kirsten A. , Zheng Hui , Fitch Kathleen V. , Looby Sara E. 
Published: November 2021

AbstractPrior studies in people living with HIV (PLWH) suggest added sweetener intake exceeds recommendations and associates with cardiometabolic abnormalities. Little is known of factors that associate with increased sweetener consumption in PLWH. This cross-sectional study explored knowledge and consumption of added sweeteners and associations of social determinants of health (SDoH) among 900 PLWH residing in the United States. Demographics, SDoH, and added sweetener knowledge and consumption were assessed via an online survey, multivariable analyses were completed. Results demonstrate that sex, race, and low educational level associated with lower sweetener knowledge. Race, age, body mass index, income, limited access to fresh fruits/vegetables, and low sweetener knowledge associated with higher sweetener consumption. Findings highlight the need for consideration of specific demographics and inequitable social circumstances when developing nutrition lifestyle strategies, inclusive of added sweetener education, that are feasible and sustainable across diverse community settings of PLWH.
Learning-by-Teaching Without Audience Presence or Interaction: When and Why Does it Work?
Authors: Lachner Andreas , Hoogerheide Vincent , van Gog Tamara , Renkl Alexander 
Published: November 2021

AbstractTeaching the contents of study materials by providing explanations to fellow students can be a beneficial instructional activity. A learning-by-teaching effect can also occur when students provide explanations to a real, remote, or even fictitious audience that cannot be interacted with. It is unclear, however, which underlying mechanisms drive learning by non-interactive teaching effects and why several recent studies did not replicate this effect. This literature review aims to shed light on when and why learning by non-interactive teaching works. First, we review the empirical literature to comment on the different mechanisms that have been proposed to explain why learning by non-interactive teaching may be effective. Second, we discuss the available evidence regarding potential boundary conditions of the non-interactive teaching effect. We then synthesize the available empirical evidence on processes and boundary conditions to provide a preliminary theoretical model of when and why non-interactive teaching is effective. Finally, based on our model of learning by non-interactive teaching, we outline several promising directions for future research and recommendations for educational practice.
Is bog water chemistry affected by increasing N and S deposition from oil sands development in Northern Alberta, Canada?
Authors: Wieder R. Kelman , Vile Melanie A. , Scott Kimberli D. , Quinn James C. , Albright Cara M. , McMillen Kelly J. , Herron Caitlyn , Fillingim Hope 
Published: November 2021

AbstractNitrogen and sulfur emissions from oil sands operations in northern Alberta, Canada have resulted in increasing deposition of N and S to the region’s ecosystems. To assess whether a changing N and S deposition regime affects bog porewater chemistry, we sampled bog porewater at sites at different distances from the oil sands industrial center from 2009 to 2012 (10-cm intervals to a depth of 1 m) and from 2009 to 2019 (top of the bog water table only). We hypothesized that: (1) as atmospheric N and S deposition increases with increasing proximity to the oil sands industrial center, surface porewater concentrations of NH4+, NO3−, DON, and SO42− would increase and (2) with increasing N and S deposition, elevated porewater concentrations of NH4+, NO3−, DON, and SO42− would be manifested increasingly deeper into the peat profile. We found weak evidence that oil sands N and S emissions affect bog porewater NH4+-N, NO3−-N, or DON concentrations. We found mixed evidence that increasing SO42− deposition results in increasing porewater SO42− concentrations. Current SO42− deposition, especially at bogs closest to the oil sands industrial center, likely exceeds the ability of the Sphagnum moss layer to retain S through net primary production, such that atmospherically deposited SO42− infiltrates downward into the peat column. Increasing porewater SO42− availability may stimulate dissimilatory sulfate reduction and/or inhibit CH4 production, potentially affecting carbon cycling and gaseous fluxes in these bogs.