bluuebunny/crossref_metadata_2025_split huggingface dataset:
Processing of Gelatin from the Skin of Pangasius hypopthalmus Using Papain Enzyme
Authors: Suparmi S , Edison E , Meivayana M 
Published: December 2021

Abstract
This study aimed to determine the processing of gelatin of catfish skin using the papain enzyme in 3 different concentrations. The method used was an experiment with a factorial Completely Randomized Design (CRD). The experiment consisted of 2 factors, namely papain enzyme concentration and the immersion time of the enzyme with 3 replications. The first factor consisted of 3 levels, namely the use of papain enzymes P1 (2%), P2 (4%) and P3 (6%). The second factor, the immersion time consisted of 3 levels of 25 minutes (W1), 35 minutes (W2) and 45 minutes (W3). The data were analyzed by using CRD. The results showed that the combination of P2W1 showed the best viscosity and gel strength (6.77 CP and 115.17 g bloom).
Enhanced photocatalytic degradation of N-doped TiO2-SiO2composite for degradation of phenol under simulated natural light assisted by S2O82-anions
Authors: Huynh Huu-Tai , Le Minh-Vien , Van Hoang Luan 
Published: December 2021

AbstractIn recent years, TiO2photocatalyst has been studied to increase the overall efficiency in the degradation of organic pollutants in water. Several solutions have been proposed such as non-metal doping to reduce a high band gap energy (3.2 eV) of TiO2to increase absorption in the visible region and synthesis of composite photocatalyst to improve the efficiency of electron-hole separation and the specific surface area. Herein, the N-doped TiO2-SiO2 photocatalysts were investigated. Powder samples with three molar ratios of TiO2/SiO2(95/5-TS5, 85/15-TS15, 75/25-TS25) were successfully synthesized, characterized, and estimated their photocatalytic activity toward the phenol degradation (initial concentration to be 10 ppm) under simulated natural light. N-doped TiO2-SiO2samples were prepared with molar ratios of N to designed TiO2to be 3%, 5%, 7%. The 3N-TS5 photocatalyst (3 mol % N doped TS5) shows the highest phenol efficiency degradation, to be 95% in 4 h, photocatalytic degradation rate constant of 1.02}10−2min−1due to its narrower band gap energy (3.05 eV). Furthermore, the addition of S2O82-anions at a concentration of 1 mM is enhanced degradation efficiency and degradation rate. And phenol is almost completely degraded within 60 min and achieved a degradation rate constant of 7.65*10−2min−1, 7.5 times higher than that without the presence of S2O82-anions. This attractive result is attributed to the generation of sulfate radical (SO4*“) during photolysis. Finally, N-doped TiO2-SiO2photocatalyst assisted by S2O82-anions shows potential to design and improve manufacturing processes to obtain photoreactors for organic degradation from waste-water under natural light degradation.
Use of wheat flour and spent coffee grounds in the production of cookies with high fiber and antioxidant content: Effects of spent coffee grounds ratio on the product quality
Authors: Trà Trấn Thi Thu , Phúc Lê Nguyên , Yến Võ Thi Ngoc , Sang Lê Thánh , Thu Nguyễn Thi Anh , Nguyệt Tôn Nữ Minh , Mẫn Lê Văn Việt 
Published: December 2021

Abstract
Spent coffee ground (SCG) is the main by-product of the instant coffee industry. In this study, wheat flour and dried SCG powder were used in the production of cookies with high fiber and antioxidant content. The objective of the study was to evaluate the effects of SCG ratio in the cookie formulation on nutritional quality, physical properties and sensory overall acceptability of the product. SCG is a rich source of dietary fiber. In 100 g dry weight of SCG, the total fiber and phenolic contents were 76.6 ± 0.58% and 3828±12 mg GAE/100g dry basis, respectively. When the SCG ratio increased from 0 to 0.25 of the composite flour weight, the dough had increased hardness and reduced adhesiveness, cohesiveness and springiness. An increase in the SCG ratio in the cookie formulation also decreased the diameter and thickness of the product but enhanced its hardness. Cookie samples supplemented with SCG had higher dietary fiber and phenolic content as well as a higher antioxidant activity than the control sample. Cookie samples were considered as high fiber food when the SCG ratio was 0.1 or higher. The use of SCG reduced the overall acceptability of cookies. When the ratio of SGC powder varied from 0.1 to 0.2, a sensory score of the obtained cookies was acceptable.
Analysis of rope based mechanism for movement of telescopic conveyor segments
Authors: Hadžikadunić Fuad 
Published: December 2021

Abstract
The subject of analysis in this paper are rope based mechanisms for the movement of the telescopic conveyors substructure. Experimental test of ropes in conjunction with pulleys on 2 telescopic conveyors were performed in order to assess the real cause of damage and cracking of ropes in a full sense, which occurred in the real application of the conveyor at the site. These are examples of two conveyors with the same characteristics on which combinations of ropes with characteristics of construction of cross section 7x19 and construction of cross section 19x7 are placed, as well as combinations of pulleys with two kinds of grooves. Some specific tests are performed that showed the best combination of construction driving system elements.
Optimization of injection parameters from the aspect of dimension accuracy
Authors: Ćoralić Amir 
Published: December 2021

Abstract
During the injection molding process, the polymers are subject to shrinkage and bending, which causes an unwanted change in geometry. These deficiencies can be caused by many factors: injection pressure, overpressure, overpressure time, cooling, etc. Within this work, the influence of overpressure and overpressure time on the accuracy of product dimensions is presented. Dimension control was performed by measuring on a 3D coordinate machine. The products are injected in 2 different combinations of parameters. For each combination of parameters, measurements were performed in five injection cycles.
Determination of the bending strength of corner joint – metal corner brace, for corps furniture made of refined panels of particleboards
Authors: Antovska Ivana , Krstev Marija , Jevtoska Elena , Gruevski Gjorgi 
Published: December 2021

Abstract
This paper presents data about the bending strength of outside corner joint – metal corner brace, for corps furniture made of refined panels of particleboard with a width of 25 mm. The research was conducted on two kinds of samples. The two kinds of sample objects are divided in two groups according to the way of composition as follows:
group 1: the first are obtained by extraction i.e. cutting up an already constructed element – bedside table which was subjected to a test method for determining strength, durability and stability-furniture for indoor use EN 1730: 2000;
group 2: the second sample objects were not subjected to any tests and were composed of two parts of particle board with given dimensions in accordance with the normative and are connected with the chosen connective object.
A web application for remote control of ROS robot based on WebSocket protocol and Django development environment
Authors: Kapić Zinaid , Crnkić Aladin , Mujčić Edin , Hamzabegović Jasna 
Published: December 2021

Abstract
The development of teleoperation systems, robots, or any physical part of the system can be costly and if something goes wrong it can lead to development overdue. Precisely for these reasons, engineers and scientists today resort to the development of simulated systems before the construction of a real system. Robot Operating System (ROS) is one of the most popular solutions for robot development, manipulation, and simulation. In this paper, we present a web application for remote control of a ROS robot. The robot is controlled via a web application that is used as a virtual Joystick. Also, in this paper, an experimental work analysis of the projected system is performed. Further research possibilities include upgrading the presented web interface, adding certain motion autonomy sensors, or integrating some path planning algorithms.
Challenges and opportunities for semiconductor and electronic design automation industry in post-Covid-19 years
Authors: Marinova Galia I , Bitri Aida K 
Published: December 2021

Abstract
The coronavirus pandemic found the semiconductor industry and the chip production supply chain ecosystem unprepared. Companies and main actors in the sector could not read the signs. The decision-makers suffered to deal with the challenges in time and take the right actions. The bullwhip effect caused by the COVID-19 destabilized the operations and some of the experts say that these problems might last and on the other side, this might open doors to innovative solutions that might change the game. The global shutdowns, the misread of the demand for electronics, underestimating customers’ demand for the automotive sector, and the Internet of Things in general, were some of the main problems causing chaos in the industry. The paper studies the state-of-the-art and the solutions offered by the semiconductor industry and by the initiatives that Europe, the USA, and especially China, took to make companies and their countries take the most out of this situation.
Numerical modelling of the bearing capacity of a beam cross-section
Authors: Demirović Besim , Hadžović Rašid , Osmić Nedim 
Published: December 2021

Abstract
The paper presents a procedure for numerical modelling of the rod cross-section bearing capacity. Equilibrium between cross sectional forces and cross-sectional stresses is determined by iterative procedures. According to the described procedure, the load-bearing capacity of the cross-section is determined according to the isotropic linear and nonlinear behavior of the material, for homogeneous and inhomogeneous cross-sections. The nonlinear behavior of the material reduces the stiffness of the cross section of the rod EA and EI, with a significant increase in the deformation values ε and κ. The applicability of the calculation and analysis of obtained results is presented using numerical examples.
Assessment of masonry structure “Radnički dom” in Mostar
Authors: Šarančić-Logo Amra , Ćećez Marko , Šahinagić-Isović Merima 
Published: December 2021

Abstract
The paper presents the assessment of the building “Radnički dom” (Workers’ Home) in Mostar, which was built in the Austro-Hungarian period, and represents one of the buildings of cultural and historical significance, located in the area of the historic urban core of the city. The paper explains the steps in assessing the condition of the existing structure, which include the collection of existing documentation, structural inspections, tests and calculations, and the assessment and decision on further action. The paper presents the drafts and gives descriptions of the performed visual inspection and the performed static calculation of the existing structure. At the end of the paper, recommendations are given for the rehabilitation and consolidation of the walls of the building: classical methods (injection and grouting) as well as modern methods (carbon strips). The paper points out the complexity of the procedure for the restoration of cultural and historical heritage buildings, the need for valid expertise of the condition and causes of building degradation, the importance of designing details of new structural elements and their corresponding and adequate connections with the original structure of the object.
Study on the effect of temperature and strain rate on Ni2FeCrCuAl high entropy alloy: a molecular dynamics study
Authors: Gowthaman S , Jagadeesha T 
Published: December 2021

Abstract
High entropy alloy has offered significant attention in various material science applications, due to its excellent material features. In this investigation, the mechanical characteristics of Ni2FeCrCuAl High Entropy Alloy (HEA) have been examined under variable temperature and strain rates to analyze its influence over the material features of high entropy alloy through Molecular Dynamics (MD) simulation and it is stated that the formation of various point defects and dislocations are the major cause for the augmentation of tensile deformation which impacts the tensile behavior of high entropy alloy. Moreover, the Radial Distribution Function (RDF) has been examined throughout tensile deformation, to investigate the impact of applied stress over the de-bonding of various atoms and it is found that the strain rate has a greater beneficial impact over the material feature trailed by the temperature outcome, owed to its superior impact on the formation of point defects and shear strain during tensile characterization.
Assessing Cognitive Decline in High-Functioning Spanish-Speaking Patients: High Score Base Rates on the Spanish-Language NIH Toolbox Cognition Battery
Authors: Karr Justin E , Mindt Monica Rivera , Iverson Grant L 
Published: December 2021

Abstract

Objective
Prior research has focused on the normal frequency of obtaining low scores on a neuropsychological test battery, but few studies have examined the normal frequency of obtaining high scores. This study involved the preparation of high score multivariate base rates for the Spanish-language National Institutes of Health (NIH) Toolbox Cognition Battery (NIHTB-CB).

Method
Participants included 250 healthy Latinx adults (age range: 19–80) from the Spanish-language NIHTB-CB normative sample who completed the full battery (two crystallized and four fluid cognition tests). Multivariate base rates, stratified by education, crystallized ability, and sociocultural characteristics, quantified the frequency at which participants obtained one or more “high” fluid test scores (i.e., ≥50th, ≥63rd, ≥75th, ≥84th, ≥91st, ≥95th, and ≥ 98th percentile).

Results
It was common for participants to obtain one or more high scores (i.e., 50.8% obtained one or more scores ≥84th percentile) and uncommon for participants to obtain “no” high scores, especially when using non-conventional thresholds for defining a high score (i.e., 10.8% obtained no scores ≥50th percentile). High scores were more commonly obtained by participants with greater education and higher crystallized ability, who were bilingual, born and educated within the United States, and from higher income households.

Conclusions
This study demonstrated that participants administered multiple neuropsychological tests commonly obtain high scores, and that the frequency of high scores varies by education, crystallized ability, and sociocultural characteristics. The absence of high scores may be indicative of cognitive impairment among examinees who are higher functioning, have greater education, and have specific sociocultural characteristics (e.g., bilingualism, higher socioeconomic status).
BRCC36 promotes intestinal mucosal barrier injury caused by BMP2 after ischemia reperfusion via inhibiting PPARγ signaling
Authors: Zhang Jin-Ming , Wang Kun-Nan , Zhang Yun , Zhang Jun-Ze , Yuan Xin-Pu , Zou Gui-Jun , Cao Zhen , Zhang Chao-Jun 
Published: December 2021

ABSTRACT
As one of the most common pathological changes in trauma and surgery practice, intestinal ischemia-reperfusion (I/R) injury is regarded as a major precipitating factor in the occurrence and development of fatal diseases. BRCA1–BRCA2-containing complex subunit 36 (BRCC36), a deubiquitinase, has been proved important in a variety of pathophysiological processes such as DNA repair, cell cycle regulation, tumorigenesis, and inflammatory response. However, the effect of BRCC36 on intestinal mucosal barrier injury after I/R has not been fully elucidated. Our research found that BRCC36 aggravated intestinal mucosal barrier injury caused by bone morphogenetic protein 2 after I/R by downregulating peroxisome proliferator-activated receptor-γ (PPARγ) signaling. These results suggested that BRCC36/PPARγ axis might serve as a potential therapeutic target for preventing intestinal mucosal barrier injury after I/R.
swCAM: estimation of subtype-specific expressions in individual samples with unsupervised sample-wise deconvolution
Authors: Chen Lulu , Wu Chiung-Ting , Lin Chia-Hsiang , Dai Rujia , Liu Chunyu , Clarke Robert , Yu Guoqiang , Van Eyk Jennifer E , Herrington David M , Wang Yue 
Published: December 2021

Abstract

Motivation
Complex biological tissues are often a heterogeneous mixture of several molecularly distinct cell subtypes. Both subtype compositions and subtype-specific (STS) expressions can vary across biological conditions. Computational deconvolution aims to dissect patterns of bulk tissue data into subtype compositions and STS expressions. Existing deconvolution methods can only estimate averaged STS expressions in a population, while many downstream analyses such as inferring co-expression networks in particular subtypes require subtype expression estimates in individual samples. However, individual-level deconvolution is a mathematically underdetermined problem because there are more variables than observations.

Results
We report a sample-wise Convex Analysis of Mixtures (swCAM) method that can estimate subtype proportions and STS expressions in individual samples from bulk tissue transcriptomes. We extend our previous CAM framework to include a new term accounting for between-sample variations and formulate swCAM as a nuclear-norm and ℓ2,1-norm regularized matrix factorization problem. We determine hyperparameter values using cross-validation with random entry exclusion and obtain a swCAM solution using an efficient alternating direction method of multipliers. Experimental results on realistic simulation data show that swCAM can accurately estimate STS expressions in individual samples and successfully extract co-expression networks in particular subtypes that are otherwise unobtainable using bulk data. In two real-world applications, swCAM analysis of bulk RNASeq data from brain tissue of cases and controls with bipolar disorder or Alzheimer’s disease identified significant changes in cell proportion, expression pattern and co-expression module in patient neurons. Comparative evaluation of swCAM versus peer methods is also provided.

Availability and implementation
The R Scripts of swCAM are freely available at https://github.com/Lululuella/swCAM. A user’s guide and a vignette are provided.

Supplementary information
Supplementary data are available at Bioinformatics online.
Niche conservatism, divergence and polyploidy inSennaseriesAphyllae(Fabaceae: Caesalpinioideae) from arid zones of South America
Authors: Robbiati Federico O , Moro Cordobés Fernando , Fortunato Renée H , Anton Ana M , Urdampilleta Juan D 
Published: December 2021

AbstractThis paper aims to integrate cytogenetic and ecological approaches into a phylogenetic framework to better understand the evolution and systematics of Senna series Aphyllae, an endemic group of arid and semi-arid regions of South America. We counted the chromosome numbers at the population level in three species of series Aphyllae using a conventional technique (GIEMSA) and in situ hybridization (FISH). Phylogenetic reconstructions and inference of chromosome evolution were based on four plastid DNA regions and one nuclear marker. A principal component analysis was carried out using environmental data. Finally, ecological niche models (ENM) were implemented: (1) to identify the abiotic factors that constraint the potential geographical distribution of series Aphyllae and (2) to understand the ecological drivers for species diversification. The basic chromosome number is x = 12. Senna aphylla showed three cytotypes with (2n = 24, 48 and 60) and S. pachyrrhiza has two cytotypes (2n = 24 and 48). Senna crassiramea appeared to be polyploid with 2n = 48. In diploid S. pachyrrhiza, two 45S and three 5S rDNA sites were reported. In tetraploid S. crassiramea, four 45S and four 5S rDNA sites were detected. The ENM and ecological speciation tests suggest that in series Aphyllae speciation was sometimes associated with conservatism and sometimes with niche divergence. Our results contribute to the evolutionary knowledge of Neotropical legumes and understanding of drivers of diversification in arid regions in South America.
Exploring dysconnectivity of the large-scale neurocognitive network across psychiatric disorders using spatiotemporal constrained nonnegative matrix factorization method
Authors: Li Ying , Zeng Weiming , Deng Jin , Shi Yuhu , Nie Weifang , Luo Sizhe , Zhang Hua 
Published: December 2021

Abstract
Psychiatric disorders usually have similar clinical and neurobiological features. Nevertheless, previous research on functional dysconnectivity has mainly focused on a single disorder and the transdiagnostic alterations in brain networks remain poorly understood. Hence, this study proposed a spatiotemporal constrained nonnegative matrix factorization (STCNMF) method based on real reference signals to extract large-scale brain networks to identify transdiagnostic changes in neurocognitive networks associated with multiple diseases. Available temporal prior information and spatial prior information were first mined from the functional magnetic resonance imaging (fMRI) data of group participants, and then these prior constraints were incorporated into the nonnegative matrix factorization objective functions to improve their efficiency. The algorithm successfully obtained 10 resting-state functional brain networks in fMRI data of schizophrenia, bipolar disorder, attention deficit/hyperactivity disorder, and healthy controls, and further found transdiagnostic changes in these large-scale networks, including enhanced connectivity between right frontoparietal network and default mode network, reduced connectivity between medial visual network and default mode network, and the presence of a few hyper-integrated network nodes. Besides, each type of psychiatric disorder had its specific connectivity characteristics. These findings provide new insights into transdiagnostic and diagnosis-specific neurobiological mechanisms for understanding multiple psychiatric disorders from the perspective of brain networks.
Risk for subsequent hypertension and cardiovascular disease after living kidney donation: is it clinically relevant?
Authors: Ferro Charles J , Townend Jonathan N 
Published: December 2021

ABSTRACT
The first successful live donor kidney transplant was performed in 1954. Receiving a kidney transplant from a live kidney donor remains the best option for increasing both life expectancy and quality of life in patients with end-stage kidney disease. However, ever since 1954, there have been multiple questions raised on the ethics of live kidney donation in terms of negative impacts on donor life expectancy. Given the close relationship between reduced kidney function in patients with chronic kidney disease (CKD) and hypertension, cardiovascular disease and cardiovascular mortality, information on the impact of kidney donation on these is particularly relevant. In this article, we review the existing evidence, focusing on the more recent studies on the impact of kidney donation on all-cause mortality, cardiovascular mortality, cardiovascular disease and hypertension, as well as markers of cardiovascular damage including arterial stiffness and uraemic cardiomyopathy. We also discuss the similarities and differences between the pathological reduction in renal function that occurs in CKD, and the reduction in renal function that occurs because of a donor nephrectomy. Kidney donors perform an altruistic act that benefits individual patients as well as the wider society. They deserve to have high-quality evidence on which to make informed decisions.