bluuebunny/crossref_metadata_2025_split huggingface dataset:
Generating Matlab looping for noise propagation prediction of environmental thermoacoustic design
Authors: Samodra FXTB , Irvansyah  
Published: April 2021

Abstract
In the proposal for designing natural ventilation of open tropical houses, environmental noise control is the simultaneous challenge. Nevertheless, the air circulation strategy for refrigerating and dehumidification can accept airborne noise transfer from sources to inside receivers once the wind direction is in the equivalent path as the noise generator. The deal concerning the design for site barrier and maintaining or preserving the tropical building material can help resolve the warm and noise environment instantaneously regardless of the diverse geographic settings. This study generates the model code of the site barrier of the tropical urban on thermoacoustic subjects as thermal and acoustics’ incorporated design. Matlab encoding is used for obtaining noise propagation control to support physiological cooling. The representative tropical buildings, Javanese housings are the case for investigating the urban built environments. The results revealed that considering the decomposition by distance remaining to geometrical propagating, the code involved diffraction, ground effect, and mitigation of sound due to atmospheric absorption. The analysis of essential factors results in the diffraction correction code as the most critical looping. The proposed overhang barrier controls the properties of the noise transmission loss and the reduction of estimation error, which causes imprecise noise management. Keywords: Matlab coding, noise barrier, thermal comfort, urban environment
Community based design for developing tourism area in the Village of Karangwuni, Wates District, Kuloprogo Regency – Yogyakarta Special Region
Authors: Bawole Paulus 
Published: April 2021

Abstract
The term tourism is used to characterize socio-cultural phenomena that include transportation, motivation, accommodation, hospitality, impact, and the economic, cultural, social, and environmental sectors that are influenced and driven by human movement. Based on this understanding, the development of a tourism area must absolutely involve the people who live in there. The participation of local people becomes a key factor in developing a tourism destination. One area that has considerable tourism potential is Karangwuni village, which is located in Wates District, Kulonprogo Regency, Yogyakarta Special Region. The area of this sub-district is 722.35 hectares and very suitable to be developed into a tourism area because of the uniqueness and there are many interesting spots that can be developed including human resources. With the new Yogyakarta International Airport in Kulonprogo, the development of the tourism area in this village is very important. This article discusses the experience of an action research method that carries out the process of designing a community-based tourism area with the objective of exploring the tourism potential that exists in the Village and afterward to be developed into sustainable tourism destinations.
A Field Measurement of Thermal Comfort in Semi Outdoor Space in Hot-Humid Climate
Authors: Munawaroh A S , Damayanti E , Prasetyo Y A 
Published: April 2021

Abstract
Thermal comfort is still important in measuring the quality of a place. Many studies have been conducted to measure thermal comfort. In addition, other studies found that thermal comfort has improved user productivities. The last study resulted that thermal comfort in semi-outdoor space in the hot, humid climate, which case study was Canteen of Universitas Bandar Lampung (UBL) have not meet the human comfort standard based on user perception. Although this canteen is a semi-outdoor space, most of the users were feeling hot when fans were not using it. This paper aims to show a present study based on field measurement in that place. The measurement is carried out by thermometer, hygrometer, and anemometer. The thermometer used to measure temperature, hygrometer used to measure humidity, and anemometer used to measure air velocity. Field measurement was done in September and done every hour during work times in five days. The analysis method was done by using https://comfort.cbe.berkeley.edu/ to calculate Sensational, Predicted Mean Vote (PMV) and Predicted Percentage Dissatisfied (PPD). JMP statistics software is used to show the trend of PMV, PPD, and Sensational based on the calculation result. This study showed thermal sensation in Outdoor was nearly neutral, thermal sensation in Semi Outdoor D was nearest to slightly warm, at the same time it was also closer to neutral than other Semi Outdoor spots. In conclusion, thermal sensation in Semi Outdoor without a wall was accepted than in Semi Outdoor with a wall. If the manager wants to improve thermal comfort at that place, they must add fans as mechanical ventilation in Semi Outdoor A, B, and C. But, if they do not want to use that, they must renovate the place by omitting the wall.
Optimization of flank wear and surface quality in the turning of 1.2343 tool steel using carbide tools coated via different methods
Authors: Özbek Nursel Altan 
Published: April 2021

Abstract
This study evaluated the effects of cutting tool coating type and process parameters on flank wear and surface roughness in the turning of hardened 1.2343 hot work tool steel. Two different coated tungsten carbide cutting tools (CVD TiCN/Al2O3/TiN and PVD TiAlN/TiN), three different cutting speeds and three different feedrates were used for the experimental tests. Turning tests were designed based on the Taguchi method (L18). Experimental results demonstrated that the PVD TiAlN/TiN tool performed better under all cutting conditions. Analysis of variance results determined the feedrate, with an impact ratio of 82.61%, to be the parameter with the most impact on surface roughness, while flank wear was most affected by the cutting tool, with 89.12%.
Three-dimensional non-equilibrium modeling of a DC multi-cathode arc plasma torch
Authors: ZHANG Zelong , WANG Cheng , SUN Qiang , XIA Weidong 
Published: April 2021

Abstract
In this paper, a three-dimensional non-equilibrium steady arc model is used to investigate the temperature, velocity and electromagnetic field in multi-cathode arc torch, and the formation mechanism of a large-area, uniform and diffused arc plasma is analyzed. The numerical simulation results show that a large volume plasma region can be formed in the central region of the generator during discharge. During this process, the maximum electron temperature appears near the cathode and in the central convergence region, while the maximum heavy particle temperature only appears in the central convergence region. This phenomenon is consistent with the experimental arc images. Near the cathode tip, the arc column is in a contraction state. In the area slightly away from the cathode, the six arc columns begin to join together. In the plasma generator, there is a large-scale current distribution in all directions of X, Y and Z, forming a stable arc plasma with a wide range of diffusion. The calculated electron temperature distribution is in good agreement with the measured electron temperature. The results suggest that the large-area diffused arc plasma in the multi-cathode arc torch is the combined effect of current distribution, convection heat transfer and heat conduction.
Design and test results of a novel quench protection circuit for a HTS ship propulsion motor
Authors: Murase Yohei , Izumi Mitsuru , Umemoto Katsuya , Oryu Tamami , Yokoyama Minoru , Yanamoto Toshiyuki 
Published: April 2021

Abstract
This paper describes a novel configuration of a quench protection circuit for a high-temperature superconducting (HTS) ship propulsion motor that can protect the HTS coils from an unexpected outage in its cryogenic cooling system. The quench protection circuit consists of conductor parts placed adjacent to the HTS coils and dump resistors and diodes placed in the cryogenic-temperature and normal-temperature areas, respectively. The conductor parts are shaped and arranged such that the magnetic coupling with the HTS coil is extremely large. Thereby, the current of the HTS coils can be instantaneously attenuated immediately after the quench protection is activated. With this configuration, the electromagnetic energy of the HTS coils can be absorbed in the dispersed parts. This can make the dump resistors smaller and make it easier to install them on a HTS ship propulsion motor. By analysing the equivalent electric circuit model of the protection circuit, we derived the conditions under which instantaneous current attenuation of the HTS coil occurs. In accordance with the conditions, we have fabricated a quench protection circuit that protects one HTS field pole of the 3 MW HTS motor developed by Kawasaki Heavy Industries. The fabricated circuit was empirically evaluated and proved to be highly effective in quench protection. The present quench protection circuit technology contributes to the practical application of HTS ship propulsion motors.
Large scale RNA-binding proteins/LncRNAs interaction analysis to uncover lncRNA nuclear localization mechanisms
Authors: Huang Yile , Qiao Yulong , Zhao Yu , Li Yuying , Yuan Jie , Zhou Jiajian , Sun Hao , Wang Huating 
Published: April 2021

AbstractLong non-coding RNAs (lncRNAs) are key regulators of major biological processes and their functional modes are dictated by their subcellular localization. Relative nuclear enrichment of lncRNAs compared to mRNAs is a prevalent phenomenon but the molecular mechanisms governing their nuclear retention in cells remain largely unknown. Here in this study, we harness the recently released eCLIP data for a large number of RNA-binding proteins (RBPs) in K562 and HepG2 cells and utilize multiple bioinformatics methods to comprehensively survey the roles of RBPs in lncRNA nuclear retention. We identify an array of splicing RBPs that bind to nuclear-enriched lincRNAs (large intergenic non-coding RNAs) thus may act as trans-factors regulating their nuclear retention. Further analyses reveal that these RBPs may bind with distinct core motifs, flanking sequence compositions, or secondary structures to drive lincRNA nuclear retention. Moreover, network analyses uncover potential co-regulatory RBP clusters and the physical interaction between HNRNPU and SAFB2 proteins in K562 cells is further experimentally verified. Altogether, our analyses reveal previously unknown factors and mechanisms that govern lincRNA nuclear localization in cells.
HelPredictor models single-cell transcriptome to predict human embryo lineage allocation
Authors: Liang Pengfei , Zheng Lei , Long Chunshen , Yang Wuritu , Yang Lei , Zuo Yongchun 
Published: April 2021

Abstract
The in-depth understanding of cellular fate decision of human preimplantation embryos has prompted investigations on how changes in lineage allocation, which is far from trivial and remains a time-consuming task by experimental methods. It is desirable to develop a novel effective bioinformatics strategy to consider transitions of coordinated embryo lineage allocation and stage-specific patterns. There are rapidly growing applications of machine learning models to interpret complex datasets for identifying candidate development-related factors and lineage-determining molecular events. Here we developed the first machine learning platform, HelPredictor, that integrates three feature selection methods, namely, principal components analysis, F-score algorithm and squared coefficient of variation, and four classical machine learning classifiers that different combinations of methods and classifiers have independent outputs by increment feature selection method. With application to single-cell sequencing data of human embryo, HelPredictor not only achieved 94.9% and 90.9% respectively with cross-validation and independent test, but also fast classified different embryonic lineages and their development trajectories using less HelPredictor-predicted factors. The above-mentioned candidate lineage-specific genes were discussed in detail and were clustered for exploring transitions of embryonic heterogeneity. Our tool can fast and efficiently reveal potential lineage-specific and stage-specific biomarkers and provide insights into how advanced computational tools contribute to development research. The source code is available at https://github.com/liameihao/HelPredictor.
A Review and Assessment of the Shared-Pathway Hypothesis for the Maintenance of Signal Honesty in Red Ketocarotenoid-Based Coloration
Authors: Powers Matthew J , Hill Geoffrey E 
Published: April 2021

Synopsis
For decades, scientists have noted connections between individual condition and carotenoid-based coloration in terrestrial and aquatic animals. Organisms that produce more vibrant carotenoid-based coloration tend to have better physiological performance and behavioral displays compared with less colorful members of the same species. Traditional explanations for this association between ornamental coloration and performance invoked the need for color displays to be costly, but evidence for such hypothesized costs is equivocal. An alternative explanation for the condition-dependence of carotenoid-based coloration, the Shared-Pathway Hypothesis (SPH), was developed in response. This hypothesis proposes that red ketocarotenoid-based coloration is tied to core cellular processes involving a shared pathway with mitochondrial energy metabolism, making the concentration of carotenoids an index of mitochondrial function. Since the presentation of this hypothesis, empirical tests of the mechanisms proposed therein have been conducted in several species. In this manuscript, we review the SPH and the growing number of studies that have investigated a connection between carotenoid-based coloration and mitochondrial function. We also discuss future strategies for assessing the SPH to more effectively disentangle evidence that may simultaneously support evidence of carotenoid-resource tradeoffs.
PIF4 negatively modulates cold tolerance in tomato anthers via temperature-dependent regulation of tapetal cell death
Authors: Pan Changtian , Yang Dandan , Zhao Xiaolin , Liu Yue , Li Mengzhuo , Ye Lei , Ali Muhammad , Yu Fangjie , Lamin-Samu Anthony Tumbeh , Fei Zhangjun , Lu Gang 
Published: April 2021

Abstract
Extreme temperature conditions seriously impair male reproductive development in plants; however, the molecular mechanisms underlying the response of anthers to extreme temperatures remain poorly described. The transcription factor phytochrome-interacting factor4 (PIF4) acts as a hub that integrates multiple signaling pathways to regulate thermosensory growth and architectural adaptation in plants. Here, we report that SlPIF4 in tomato (Solanum lycopersicum) plays a pivotal role in regulating cold tolerance in anthers. CRISPR (clustered regularly interspaced short palindromic repeats)–associated nuclease Cas9-generated SlPIF4 knockout mutants showed enhanced cold tolerance in pollen due to reduced temperature sensitivity of the tapetum, while overexpressing SlPIF4 conferred pollen abortion by delaying tapetal programmed cell death (PCD). SlPIF4 directly interacts with SlDYT1, a direct upstream regulator of SlTDF1, both of which (SlDYT1 and SlTDF1) play important roles in regulating tapetum development and tapetal PCD. Moderately low temperature (MLT) promotes the transcriptional activation of SlTDF1 by the SlPIF4–SlDYT1 complex, resulting in pollen abortion, while knocking out SlPIF4 blocked the MLT-induced activation of SlTDF1. Furthermore, SlPIF4 directly binds to the canonical E-box sequence in the SlDYT1 promoter. Collectively, these findings suggest that SlPIF4 negatively regulates cold tolerance in anthers by directly interacting with the tapetal regulatory module in a temperature-dependent manner. Our results shed light on the molecular mechanisms underlying the adaptation of anthers to low temperatures.
Assessments of Physicians’ Electrocardiogram Interpretation Skill: A Systematic Review
Authors: Cook David A. , Oh So-Young , Pusic Martin V. 
Published: April 2021

PurposeTo identify features of instruments, test procedures, study design, and validity evidence in published studies of electrocardiogram (ECG) skill assessments.MethodThe authors conducted a systematic review, searching MEDLINE, Embase, Cochrane CENTRAL, PsycINFO, CINAHL, ERIC, and Web of Science databases in February 2020 for studies that assessed the ECG interpretation skill of physicians or medical students. Two authors independently screened articles for inclusion and extracted information on test features, study design, risk of bias, and validity evidence.ResultsThe authors found 85 eligible studies. Participants included medical students (42 studies), postgraduate physicians (48 studies), and practicing physicians (13 studies). ECG selection criteria were infrequently reported: 25 studies (29%) selected single-diagnosis or straightforward ECGs; 5 (6%) selected complex cases. ECGs were selected by generalists (15 studies [18%]), cardiologists (10 studies [12%]), or unspecified experts (4 studies [5%]). The median number of ECGs per test was 10. The scoring rubric was defined by 2 or more experts in 32 studies (38%), by 1 expert in 5 (6%), and using clinical data in 5 (6%). Scoring was performed by a human rater in 34 studies (40%) and by computer in 7 (8%). Study methods were appraised as low risk of selection bias in 16 studies (19%), participant flow bias in 59 (69%), instrument conduct and scoring bias in 20 (24%), and applicability problems in 56 (66%). Evidence of test score validity was reported infrequently, namely evidence of content (39 studies [46%]), internal structure (11 [13%]), relations with other variables (10 [12%]), response process (2 [2%]), and consequences (3 [4%]).ConclusionsECG interpretation skill assessments consist of idiosyncratic instruments that are too short, composed of items of obscure provenance, with incompletely specified answers, graded by individuals with underreported credentials, yielding scores with limited interpretability. The authors suggest several best practices.
Detection of hepatitis B virus-host junction sequences in urine of infected patients
Authors: Lin Selena Y. , Su Yih-Ping , Trauger Evan R. , Song Benjamin P. , Thompson Emilie G. C. , Hoffman Malcolm C. , Chang Ting-Tsung , Lin Yih-Jyh , Kao Yu-Lan , Cui Yixiao , Hann Hie-Won , Park Grace , Song Wei , Su Ying-Hsiu 
Published: April 2021

ABSTRACTBackground & AimsIntegrated hepatitis B virus (HBV) DNA, found in >85% of HBV-associated hepatocellular carcinomas (HBV-HCC), can play a significant role in HBV-related liver disease progression. HBV-host junction sequences (HBV-JS’s), created through integration events, have been used to determine HBV-HCC clonality. Here, we investigate the feasibility of analyzing HBV integration in a noninvasive urine liquid biopsy.Approach & ResultsUtilizing an HBV-targeted NGS assay, we first identified HBV-JS’s in 8 HBV-HCC tissues and designed short-amplicon junction-specific PCR assays to detect HBV-JSs in matched urine. We detected and validated tissue-derived junctions in 5 of 8 matched urine samples. Next, we screened 32 urine samples collected from 25 HBV-infected patients (5 with hepatitis, 10 with cirrhosis, 4 with HCC, and 6 post-HCC). Encouragingly, all 32 urine samples contained HBV-JS’s detectable by HBV-targeted NGS. Of the 712 total HBV-JS’s detected in urine, 351 were in gene-coding regions, 11 of which, including TERT, had previously been reported as recurrent integration sites in HCC tissue and were found in urine of cirrhosis or HCC patients only. The integration breakpoints of HBV DNA detected in urine were found predominantly (∼70%) at a previously identified integration hotspot, HBV DR1-2.ConclusionsHBV viral-host junction DNA can be detected in urine of HBV-infected patients. This study is the first study to demonstrate the potential for a noninvasive urine liquid biopsy of integrated HBV DNA to monitor HBV-infected patients for HBV-associated liver diseases and the efficacy of antiviral therapy.
Shared services: configurations, dynamics and performance
Authors: Richter Philipp 
Published: April 2021

PurposeThe purpose of this paper is to explore the configurations of shared service center (SSC) characteristics, their performance implications and the dynamics of SSC configurations during their implementation.Design/methodology/approachThis study uses the capability-based view and configurational approach to suggest a model that explains performance outcomes of shared service configurations. Survey data are analyzed with a cluster analysis to examine shared service configurations in distinct stages of implementation. Moreover, a lifecycle framework of shared service configurations is conceptualized.FindingsThis study considers shared service configurations as operational capabilities to run corporate support activities. The purpose is to examine the configurations of those capabilities, their performance implications and their dynamics during the shared service implementation.Practical implicationsThe findings help senior executives to effectively implement and transform shared services when deciding to renew corporates' support activities.Originality/valueThis study is one of the first that conceptually and empirically explores shared service configurations, performance and configurational dynamics.