bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultrasonography for noninvasive and real-time evaluation of peri-implant soft and hard tissue: a case series
Authors: Thöne-Mühling Miriam , Kripfgans Oliver D. , Mengel Reiner 
Published: September 2021

Abstract
Background
The diagnosis of soft and hard tissue at dental implants will be challenging in the future, as high prevalence of mucositis and peri-implantitis were described in the population. Ultrasonography is a promising non-invasive, inexpensive, painless, and radiation-free method for imaging hard and soft tissue at implants, especially an ultrasound device with a 25-MHz probe demonstrating a high correlation between ultrasound, clinical, and radiological measurements.

Case presentation
The following case series demonstrates the use of ultrasonography with high spatial resolution probe in patients with dental implants affected by soft tissue recession and/or crestal bone loss.

Conclusion
These ultrasound images can provide valuable additional information for the assessment of peri-implant soft and hard tissue.
Morphology of lentic and lotic tadpoles from Madagascar
Authors: Laudor Jörn , Schulze Arne , Veith Michael , Viertel Bruno , Elle Ortwin , Lötters Stefan 
Published: September 2021

Abstract
Background
The morphology of anuran larvae is suggested to differ between species with tadpoles living in standing (lentic) and running (lotic) waters. To explore which character combinations within the general tadpole morphospace are associated with these habitats, we studied categorical and metric larval data of 123 (one third of which from lotic environments) Madagascan anurans.

Results
Using univariate and multivariate statistics, we found that certain combinations of fin height, body musculature and eye size prevail either in larvae from lentic or lotic environments.

Conclusion
Evidence for adaptation to lotic conditions in larvae of Madagascan anurans is presented. While lentic tadpoles typically show narrow to moderate oral discs, small to medium sized eyes, convex or moderately low fins and non-robust tail muscles, tadpoles from lotic environments typically show moderate to broad oral discs, medium to big sized eyes, low fins and a robust tail muscle.
Intra-operative intravascular effect of the difference in colloid solutions during acute normovolemic hemodilution
Authors: Midorikawa Yoko , Saito Junichi , Kitayama Masato , Toyooka Kentaro , Hirota Kazuyoshi 
Published: September 2021

Abstract
Background
Acute normovolemic hemodilution (ANH) is used to reduce the risk of peri-operative allogeneic blood transfusion. Although crystalloid and/or colloid solutions have been used for volume replacement during ANH, no studies have examined the differences among solutions on the volume status, electrolytes, acid-base balance, and hemodynamic status during surgery with ANH.

Methods
We retrospectively compared the effect of Ringer’s lactate with 3% dextran-40 (Saviosol®, DEX group) and 6% hydroxyethyl starch 130/0.4 in 0.9% sodium chloride (Voluven®, HES group) on blood hemoglobin serum electrolytes and estimated blood volume before induction of anesthesia (baseline), after ANH and after blood transfusion following surgery in patients undergoing open gynecological surgery (n = 111 and 67, respectively). The primary outcomes were the changes in hemoglobin and electrolytes after ANH.

Results
There were no differences in hemoglobin or electrolytes between the two groups at baseline. Postoperative hemoglobin was significantly higher (11.0 ± 1.5 g/dL vs 9.9 ± 1.3 g/dL) (mean ± SD) in the DEX group than in the HES group (p = 0.03). Postoperative potassium was significantly decreased from the baseline both in the DEX group (137.9 ± 2.5 mmol/L vs 136.3 ± 2.7 mmol/L) and in the HES group (138.3 ± 2.0 mmol/L vs 137.8 ± 2.5 mmol/L) (p < 0.001 for both); however, it was significantly higher than in the DEX group after surgery (p < 0.001). Estimated blood volume after surgery was significantly increased after ANH in both groups; however, it was larger in the HES group than in the DEX group.

Conclusions
Postoperative hemoglobin and potassium were significantly higher, and estimated blood volume was significantly smaller in the DEX than in the HES group.
Location and solar system parameter extraction from power measurement time series
Authors: Danner Philipp , de Meer Hermann 
Published: September 2021

AbstractPhotovoltaic (PV) systems are considered an important pillar in the energy transition because they are usually located near the consumers. In order to provide accurate PV system models, e.g. for microgrid simulation or hybrid-physical forecast models, it is of high importance to know the underlying PV system parameters, such as location, panel orientation and peak power. In most open PV generation databases, these parameters are missing or are inaccurate.In this paper, we present a framework based on particle swarm optimisation and the PVWatts model to estimate PV system parameters using only power feed-in measurements and satellite-based ERA5 climate reanalysis data. Our sensitivity analysis points out the most relevant PV system parameters, which are panel and inverter peak power, panel orientation, system location and a small but not negligible influence of ambient temperature and albedo. The detailed evaluation on one exemplary PV system shows an acceptable accuracy in panel azimuth and tilt for the use in microgrid PV system simulation. The extracted location has less than 25 km of positioning error in the best case, which is more than satisfying with respect to the underlying data resolution of the ERA5 dataset. Similar results are observed for 10 systems in Europe and the USA.
Socio-technical modeling of smart energy systems: a co-simulation design for domestic energy demand
Authors: Barsanti Matteo , Schwarz Jan Sören , Gérard Constantin Lionel Guy , Kasturi Pranay , Binder Claudia R. , Lehnhoff Sebastian 
Published: September 2021

AbstractTo tackle the climate crisis, the European energy strategy relies on consumers taking ownership of the energy transition, accelerating decarbonisation through investments in low-carbon technologies and ensuring system stability and reliability by actively participating in the market. Therefore, tools are needed to better understand an increasingly complex and actor-dense energy system, tracking socio-technical dynamics that occur at its margins and then predicting the effects on larger scales. Yet, existing domestic energy demand models are not flexible enough to incorporate a wide range of socio-technical factors, and to be incorporated into larger energy system simulation environments. Here, a co-simulation design for domestic energy demand modeling is presented and motivated on the basis of four design principles: granularity, scalability, modularity and transparency. Microsimulation of domestic energy demand, through the Python open source library demod, shows that it is possible to achieve high detail and high temporal resolution without compromising scalability. Furthermore, mosaik, an open source co-simulation framework, makes it possible to generate, integrate and orchestrate a multitude of demod-based instances with other independent models, which for the illustrative purposes of this study are represented by a heat pump model. The authors hope that the detailed documentation of the proposed solution will encourage interdisciplinary and collaborative efforts to develop a simulation ecosystem capable of investigating alternative energy transition pathways and evaluating policy interventions through the socio-technical lens.
Isolated thalamic stroke – analysis of clinical characteristics and asymmetry of lesion distribution in a retrospective cohort study
Authors: Schaller-Paule Martin A. , Oeckel Ariane Martinez , Schüre Jan-Rüdiger , Keil Fee , Hattingen Elke , Foerch Christian , Rauch Maximilian 
Published: September 2021

Abstract
Background
More patients with left-hemispheric than right-hemispheric strokes are admitted to hospitals. This is due to the easier recognition of cortical symptoms of the dominant-hemisphere. The thalamus constitutes a “micro-model” of the brain cortex with structure-function relationships known to be asymmetric, especially for language, memory, and visuo-spatial neurocognitive functions. The goal of this study was to characterize clinical symptoms and lesion distribution patterns of patients with acute isolated thalamic stroke (ITS) and to evaluate whether left-sided lesions are overrepresented in the hospital.

Methods
We performed a radiological database search including all brain scans performed in the Center of Neurology and Neurosurgery of the University Hospital Frankfurt between 2010 and 2019. A total of 5733 patients presenting with acute ischemic stroke were screened for ITS. Based on the MRI data, a lesion-overlap map was then generated to visualize the ITS lesion distribution.

Results
Fifty-eight patients with unilateral ITS were identified. A majority of 38 patients (65.5%) showed left-sided ITS, whereas only 20 patients (34.5%) had right-sided ITS (p = 0.012). A particular difference was found for ITS lesions in the anterior thalamus of the anterolateral (n = 10) and anteromedian (n = 3) vascular territory, which were located in the left thalamus in 85% of patients (p = 0.011). No distribution difference was found for ITS lesions in the inferomedial (n = 7), central (n = 8), inferolateral (n = 23) and posterior (n = 7) vascular territories. The neuropsychological symptoms of thalamic aphasia (n = 8), neurocognitive impairment (n = 6), behavioral changes (n = 2), neglect (n = 2) and memory deficits (n = 3) were described predominantly in patients with left-sided ITS (p < 0.01). In contrast, other stroke symptoms (e.g., sensorimotor hemi-syndromes) did not reveal a side preponderance.

Conclusions
The better recognizability of left anterior compared to right anterior thalamic stroke symptoms may have an impact on the frequency in which ITS patients are admitted to the hospital. Clinical characteristics of right anterior thalamic stroke should therefore be further investigated, and diagnostic instruments towards their detection be identified.
Understanding the barriers to NET-ZERO transport for rural roads: a Northern Ireland case study
Authors: Lydon Myra , Lydon Darragh , Stevens Nicola-Ann , Taylor Su , Early Juliana , Marshall Adele 
Published: September 2021

Abstract
Introduction
Climate-related disasters have cost the world over £450 billion over the last 3 years. In the race to mitigate these effects, the UK government has committed to net-zero emissions by 2050. Transport provides the largest single sector contribution to CO2 emissions, the road network accounts for up to 91%. As the only UK country without a formal climate change bill Northern Ireland could compromise the overall effort.

Case description
In this research a survey of road asset owners, managers, academics, consultants, public transport providers was undertaken to seek to understand the current barriers to adapting a dispersed rural road network in Northern Ireland for net-zero transport. The survey data was collected though an online form with a combination of multiple choice and open ended questions. Thematic analysis was used to code and analyse the data collected which enabled a discussion around the key expert opinions gathered.

Discussion and evaluation
The paper presents details of the current road network in Northern Ireland and highlights some of the issues faced by asset owners. The survey questions were developed though engagement with transport professionals in Northern Ireland and focus predominantly on road use rather than the impact of current land management practices or environmental conditions such as flood risk. The response highlights a clear enthusiasm for change in the operation of the public road network which is hindered by a lack of government strategy and limited public consultation.

Conclusions
The high response rate (41%) for the survey highlights the interest of those in the transport sector to engage in activities which can support a better understanding of how road networks contribute to CO2 emissions. Within the survey data a requirement for behavioural change was highlighted as a key step to reduce transport related emissions, the enthusiasm for change demonstrates this is the optimum time to engage with the public and develop clear transport strategies. More accurate findings and empirical evidence could have been established had the study considered specific, transport planning, environmental and land use conditions for Northern Ireland. This will be the focus of further research in this area to enable clear translation of the research to other countries.
The color of magnetic monopole noise
Authors: Nisoli Cristiano 
Published: September 2021

Abstract
We relate the anomaly in the noise color of spin ice to the emergent nature of its magnetic monopoles and their non-trivial random walk. Monopoles are quasi-particles, and the spin vacuum in which they wander is not structureless. Rather, the underlying spin ensemble filters the thermal white noise, leading to non-trivial coevolution. Thus, monopoles can be considered as “dressed” random walkers, activated by a non-trivial stochastic force that subsumes mutual interactions and the coevolution of their spin vacuum. From this, we suggest that recent experimental results are interpretable in terms of monopole subdiffusion. We then conjecture relations between the color of the noise and other observables, such as relaxation time, monopole density, the dynamic exponent, and the order of the annihilation reaction, which suggests to us the introduction of spin-ice–specific critical exponents in a neighborhood of the ice manifold criticality.
Estimating the number of undetected COVID-19 cases among travellers from mainland China
Authors: Bhatia Sangeeta , Imai Natsuko , Cuomo-Dannenburg Gina , Baguelin Marc , Boonyasiri Adhiratha , Cori Anne , Cucunubá Zulma , Dorigatti Ilaria , FitzJohn Rich , Fu Han , Gaythorpe Katy , Ghani Azra , Hamlet Arran , Hinsley Wes , Laydon Daniel , Nedjati-Gilani Gemma , Okell Lucy , Riley Steven , Thompson Hayley , van Elsland Sabine , Volz Erik , Wang Haowei , Wang Yuanrong , Whittaker Charles , Xi Xiaoyue , Donnelly Christl A. , Ferguson Neil M. 
Published: September 2021

Background: As of August 2021, every region of the world has been affected by the COVID-19 pandemic, with more than 196,000,000 cases worldwide. Methods: We analysed COVID-19 cases among travellers from mainland China to different regions and countries, comparing the region- and country-specific rates of detected and confirmed cases per flight volume to estimate the relative sensitivity of surveillance in different regions and countries. Results: Although travel restrictions from Wuhan City and other cities across China may have reduced the absolute number of travellers to and from China, we estimated that up to 70% (95% CI: 54% - 80%) of imported cases could remain undetected relative to the sensitivity of surveillance in Singapore. The percentage of undetected imported cases rises to 75% (95% CI 66% - 82%) when comparing to the surveillance sensitivity in multiple countries. Conclusions: Our analysis shows that a large number of COVID-19 cases remain undetected across the world. These undetected cases potentially resulted in multiple chains of human-to-human transmission outside mainland China.
Means and Methods of Dosimetry of High-Energy Neutron Radiation on Proton Accelerators
Authors: Tsoviyanov Aleksandr , Komarov A. , Gantsovskii P. , Alexeev A. , Popchenko M. , Zhuravleva V. , Bogdanenko N. 
Published: September 2021

The main common means and methods of neutron radiation dosimetry.
Consideration of various means and methods for detecting high-energy neutron radiation:
● Activation
● Tracking
● Bubble detectors
● TEPC
● Moderator + converter
Effect of the Sharrard procedure on hip instability in children with down syndrome: A retrospective study
Authors: Mulder Frederike E.C.M. , Bok Levinus A. , van Douveren Florens Q.M.P. , Pruijs Hans E.H. , Zeegers Adelgunde V.C.M. 
Published: September 2021

Purpose The aim of this study was to retrospectively analyze the effect of the Sharrard procedure on hip instability in children with Down syndrome (DS), as measured by the migration index. Methods In total, 17 children (21 hips) were included from six hospitals in the Netherlands between 2003 and 2019. The primary outcome, hip instability, was assessed with the Reimers’ migration index on preoperative and postoperative plain anteroposterior pelvic radiographs. The mean age at surgery was 8.1 years, the majority of children were male (64.7%) and the mean follow-up time was 7.3 years. Results The mean preoperative migration index was 46% (sd 23.5) and the mean postoperative migration index was 37% (sd 28.4). The mean Delta migration index (the difference in pre-operative migration index and most recent post-operative migration index) showed an improvement of 9.3% (sd 22.7). An improvement in migration index was observed in 52%, no change in 29% and deterioration in 19% of hips. No (re)dislocations occurred in 91% of the hips. No major complications were observed during the follow-up period. Conclusion Early intervention is warranted in children with DS showing hip instability or hip migration, in order to succeed with less complex procedures. The Sharrard procedure should be considered in children with DS showing hip instability or hip migration, since it aims to rebalance the muscles of the hip joint, is less complex than bony procedures of the femur and acetabulum, surgery time is often shorter, there are fewer major complications and the rehabilitation period is shorter. Level of Evidence IV - retrospective case series
Low-intensity pulsed ultrasound therapy suppresses coronary adventitial inflammatory changes and hyperconstricting responses after coronary stent implantation in pigs in vivo
Authors: Watanabe Tasuku , Matsumoto Yasuharu , Nishimiya Kensuke , Shindo Tomohiko , Amamizu Hirokazu , Sugisawa Jun , Tsuchiya Satoshi , Sato Koichi , Morosawa Susumu , Ohyama Kazuma , Watanabe-Asaka Tomomi , Hayashi Moyuru , Kawai Yoshiko , Takahashi Jun , Yasuda Satoshi , Shimokawa Hiroaki 
Published: September 2021

Backgrounds
We demonstrated that coronary adventitial inflammation plays important roles in the pathogenesis of drug-eluting stent (DES)-induced coronary hyperconstricting responses in pigs in vivo. However, no therapy is yet available to treat coronary adventitial inflammation. We thus developed the low-intensity pulsed ultrasound (LIPUS) therapy that ameliorates myocardial ischemia by enhancing angiogenesis.

Aims
We aimed to examine whether our LIPUS therapy suppresses DES-induced coronary hyperconstricting responses in pigs in vivo, and if so, what mechanisms are involved.

Methods
Sixteen normal male pigs were randomly assigned to the LIPUS or the sham therapy groups after DES implantation into the left anterior descending (LAD) coronary artery. In the LIPUS group, LIPUS (32 cycles, 193 mW/cm2) was applied to the heart at 3 different levels (segments proximal and distal to the stent edges and middle of the stent) for 20 min at each level for every other day for 2 weeks. The sham therapy group was treated in the same manner but without LIPUS. At 4 weeks after stent implantation, we performed coronary angiography, followed by immunohistological analysis.

Results
Coronary vasoconstricting responses to serotonin in LAD at DES edges were significantly suppressed in the LIPUS group compared with the sham group. Furthermore, lymph transport speed in vivo was significantly faster in the LIPUS group than in the sham group. Histological analysis at DES edges showed that inflammatory changes and Rho-kinase activity were significantly suppressed in the LIPUS group, associated with eNOS up-regulation and enhanced lymph-angiogenesis.

Conclusions
These results suggest that our non-invasive LIPUS therapy is useful to treat coronary functional abnormalities caused by coronary adventitial inflammation, indicating its potential for the novel and safe therapeutic approach of coronary artery disease.
Evaluation of knowledge, awareness and attitudes towards breast cancer risk factors and early detection among females in Bangladesh: A hospital based cross-sectional study
Authors: Alam Nur E. , Islam Md. Shariful , Ullah Hedayet , Molla Md. Tarek , Shifat Siratul Kubra , Akter Sumaiya , Aktar Salma , Khatun Mst. Mahmuda , Ali Md. Rayhan , Sen Tapon Chandra , Chowdhury Kamal , Pervin Rehana , Mohiuddin A. K. M. 
Published: September 2021

Background
Breast cancer (BCa) is a leading cause of mortality among women in Bangladesh. Many young women in Bangladesh have poor knowledge about breast cancer screening, including risk factors, warning signs/symptoms, diagnosis and early detection. We investigated awareness about breast cancer risk factors as a screening tool among women at the Sheikh Hasina Medical College (SHMC) of Tangail district in Bangladesh.

Methods
A cross sectional survey was conducted to collect data via a structured questionnaire from SHMC during the period of February to December 2019. A total of 1,007 participants (aged 33.47 (±12.37 years)) was considered for data analysis.

Results
Of the 1,007 women, about 50% were knowledgeable about the risk factors. Pain in the breast was identified as the most commonly warning sign/symptom of breast cancer. Only 32.2% of respondents knew at least one breast cancer screening method. The mean knowledge was scored 3.43 ± 2.25 out of a total possible score of 8. Awareness of BCa was associated with residence, family history of breast cancer, marital, literacy and socio-economic status (p <0.05). Only 14.7% of women who knew about BSE said they were conducting regular breast self-examination. Unmarried women (aOR: 2.971; 95% CI: 1.108–7.968) were more likely to have performed BSE compared to married women (p <0.05).

Conclusion
Although most participants were aware of breast cancer; knowledge about risk factors, warning signs/symptoms, early diagnosis and detection was relatively poor. Knowledge about performing BSE was particularly low. This highlights the importance of increasing awareness about breast cancer risk factors and early detection among young women in Bangladesh.
lncRNA NEAT1 regulates CYP1A2 and influences steroid-induced necrosis
Authors: Zhou Yongfang , Zhang Fei , Xu Fengyang , Wang Qiang , Wu Jianhua , Peng Wuxun , Dong Wentao 
Published: September 2021

Abstract
The main cause of steroid-induced necrosis of femoral head (SNFH) is excessive glucocorticoid (GC) intake. The aim of this article was to investigate the role of lncRNA NEAT1 as a molecular sponge to adsorb miR-23b-3p and regulate CYP1A2 in SNFH. Fluorescence in situ hybridization was used to localize lncRNA NEAT1. Human bone marrow mesenchymal stem cells (hBMSCs) were collected from patients with SNFH. The expression of lncRNA NEAT1, miR-23b-3p and CYP1A2 in hBMSCs were intervened. Compared to the control group, the lncRNA NEAT1 and CYP1A2 expression in the SNFH group was increased, while miR-23b-3p expression was decreased. GCs could inhibit the osteogenic differentiation of hBMSCs and upregulate the expression of lncRNA NEAT1. Knockdown of lncRNA NEAT1 could promote the proliferation and osteogenic differentiation of hBMSCs in the SNFH group. Overexpression of miR-23b-3p could partially counteract the effect of lncRNA NEAT1 on hBMSCs. CYP1A2 was confirmed to be a target of miR-23b-3p. Overexpression of CYP1A2 could partially rescue the effect of miR-23b-3p overexpression on hBMSCs. In conclusion, lncRNA NEAT1 as a ceRNA can adsorb miR-23b-3p and promote the expression of CYP1A2, which then inhibits the osteogenic differentiation of hBMSCs and promotes the progress of SNFH.