bluuebunny/crossref_metadata_2025_split huggingface dataset:
The biological prospective of red-pigmented bacteria cultured from contaminated agar media
Authors: Arifiyanto Achmad , AFRIANI HAPIN , PUTRI MEISHY HANDERLIN , DAMAYANTI BERLIANA , RIYANTO CINDY LUKYTA RATIH 
Published: February 2021

Abstract. Arifiyanto A, Afriani H, Putri MH, Damayanti B, Riyanto CL. 2021. The biological prospective of red-pigmented bacteria cultured from contaminated agar media. Biodiversitas 22: 1152-1159. Contaminated agar media was often depleted due to the growth of microbes, which is undesirable for culture. However, the contaminating microbes usually have a distinctive morphology. This research aimed to identify the potential of red-pigmented bacteria originated from the contamination of Drosophila melanogaster larvae. Fruit fly larvae that grow on contaminated tryptic soy agar were accompanied by the appearance of the red-pigmented bacteria colony. The bacterial colonies were purified by the re-streaking method on tryptic soybean agar. This strain was characterized morphologically, biochemically, and molecularly. Results showed that the MBC1 strain was identified as Serratia marcescens. The various metal susceptibility tests at 25 ppm did not affect the growth of the MBC1 strain. Meanwhile, it was also able to inhibit the growth of certain pathogens such as Aspergillus niger, Candida sp., Fusarium sp., and Rigidoporous sp. Strain MBC1 was able to produce antioxidant compounds. The lipolytic and amylolytic activity can be developed for bioremediate agriculture waste and biosurfactant production.
Estimating the effective pressure from nanosecond laser-induced breakdown in water
Authors: Li Fabing , Wang Ying , Zhao Haiying , Xu Xin , Liu Cunming , Men Zhiwei , Sun Chenglin 
Published: February 2021

Nanosecond laser-induced breakdown (LIB) in liquids (e.g., water) can produce dynamic high pressure and high temperature. However, since high pressure needs to negate the effect of high temperature to some degree, it is only partially effective. As a result, it is difficult to directly measure the effective pressure due to the transient and complex LIB process. Here, we presented a simple method based on Raman spectroscopy to indirectly determine the effective pressure caused by LIB in liquid pure

H

2

O

and low concentration

H

2

O

−

H

2

O

2

mixtures. By comparing the Raman shifts of the ice-VII mode for pure

H

2

O

and

H

2

O

−

H

2

O

2

mixtures under laser pumping and static high pressure, the LIB effective pressure can be first estimated. The empirical equation was then derived base on the correlation of the LIB effective pressure to ice-VII-point stimulated Raman scattering thresholds for pure and mixture water solutions, which can be used to estimate the LIB effective pressures for other different mixture water solutions with the uncertainty of 0.14–0.25 Gpa. Hopefully, our study here would advance the measurements of effective pressure in the LIB process.
Dynamically reversible and strong circular dichroism based on Babinet-invertible chiral metasurfaces
Authors: Luo Xiaoqing , Hu Fangrong , Li Guangyuan 
Published: February 2021

We propose a Babinet-invertible chiral metasurface for achieving dynamically reversible and strong circular dichroism (CD). The proposed metasurface is composed of a

V
O

2

–metal hybrid structure, and when

V
O

2

transits between the dielectric state and the metallic state, the metasurface unit cell switches between complementary structures that are designed according to Babinet’s principle. This leads to a large and reversible CD tuning range between

±
0.5

at 0.97 THz, which is larger than the one found in the literature. We attribute the CD effect to extrinsic chirality of the proposed metasurface. We envision that the Babinet-invertible chiral metasurface proposed here will advance the engineering of active and tunable chiro-optical devices and promote their applications.
Association of socioeconomic deprivation with asthma care, outcomes, and deaths in Wales: A 5-year national linked primary and secondary care cohort study
Authors: Alsallakh Mohammad A. , Rodgers Sarah E. , Lyons Ronan A. , Sheikh Aziz , Davies Gwyneth A. 
Published: February 2021

Background
Socioeconomic deprivation is known to be associated with worse outcomes in asthma, but there is a lack of population-based evidence of its impact across all stages of patient care. We investigated the association of socioeconomic deprivation with asthma-related care and outcomes across primary and secondary care and with asthma-related death in Wales.

Methods and findings
We constructed a national cohort, identified from 76% (2.4 million) of the Welsh population, of continuously treated asthma patients between 2013 and 2017 using anonymised, person-level, linked, routinely collected primary and secondary care data in the Secure Anonymised Information Linkage (SAIL) Databank. We investigated the association between asthma-related health service utilisation, prescribing, and deaths with the 2011 Welsh Index of Multiple Deprivation (WIMD) and its domains. We studied 106,926 patients (534,630 person-years), 56.3% were female, with mean age of 47.5 years (SD = 20.3). Compared to the least deprived patients, the most deprived patients had slightly fewer total asthma-related primary care consultations per patient (incidence rate ratio [IRR] = 0.98, 95% CI 0.97–0.99, p-value < 0.001), slightly fewer routine asthma reviews (IRR = 0.98, 0.97–0.99, p-value < 0.001), lower controller-to-total asthma medication ratios (AMRs; 0.50 versus 0.56, p-value < 0.001), more asthma-related accident and emergency (A&E) attendances (IRR = 1.27, 1.10–1.46, p-value = 0.001), more asthma emergency admissions (IRR = 1.56, 1.39–1.76, p-value < 0.001), longer asthma-related hospital stay (IRR = 1.64, 1.39–1.94, p-value < 0.001), and were at higher risk of asthma-related death (risk ratio of deaths with any mention of asthma 1.56, 1.18–2.07, p-value = 0.002). Study limitations include the deprivation index being area based and the potential for residual confounders and mediators.

Conclusions
In this study, we observed that the most deprived asthma patients in Wales had different prescribing patterns, more A&E attendances, more emergency hospital admissions, and substantially higher risk of death. Interventions specifically designed to improve treatment and outcomes for these disadvantaged groups are urgently needed.
Fluctuations in influenza-like illness epidemics and suicide mortality: A time-series regression of 13-year mortality data in South Korea
Authors: Jung Sun Jae , Lim Sung-Shil , Yoon Jin-Ha 
Published: February 2021

AimsWe explored the association between influenza epidemic and suicide mortality rates in a large population using a time-series regression of 13-year mortality data in South Korea.MethodsWeekly suicide mortalities and influenza-like illness (ILI) were analyzed using time series regression. Regression coefficient for suicide mortality based on percentage change of ILI was calculated using a quasi-Poisson regression. Non-linear distributed lag models with quadratic function up to 24 weeks were constructed.ResultsThe association between ILI and suicide mortality increased significantly up to 8 weeks post-influenza diagnosis. A significant positive association between ILI and suicide mortality was observed from 2009, when a novel influenza A(H1N1)pdm09 virus provoked a worldwide pandemic. No meaningful association between these factors was observed before 2009.ConclusionThere was a significant positive relationship between ILI and suicide mortality after 2009, when a novel influenza A(H1N1)pdm09 virus provoked a worldwide pandemic.
Effects of Adachi Rehabilitation Programme on older adults under long-term care: A multi-centre controlled trial
Authors: Baba Yoshihiko , Ooyama Chika , Tazawa Yasushi , Kohzuki Masahiro 
Published: February 2021

Objectives
We developed the Adachi Rehabilitation Programme (ARP), a community rehabilitation program. Under the supervision of professional caregivers, older adults cleaned and planted flowers in the park and they walked and shopped in the community. We examined the effects of ARP on individuals receiving small-group multifunctional at-home care at community facilities.

Methods
This was a multi-centre controlled trial at thirteen small multifunctional at-home care facilities in Adachi, Tokyo. The primary outcomes of the study were daily step counts and timed up & go (TUG). Secondary outcomes included gait speed, step length, Barthel Index for Activities of Daily Living, Functional Independence Measure, Mini-Mental State Examination (MMSE) and EuroQOL 5 Dimension.

Results
Ninety-six individuals at thirteen small multifunctional at-home care facilities were recruited for participation in December 2017. They were allocated to intervention (38) and control (40) groups. The average daily step count of the control group decreased from 852 to 727, but it increased by approximately 650 steps, from 990 to 1635, for the intervention group. Average TUG decreased from 16.1 s to 14.0 s and MMSE score increased from 15.9 to 16.3 for the intervention group, but a significant interaction was not found. On non-intervention home days, the daily step counts of the intervention group increased significantly from 908 steps to 1485 steps, while those of the control group decreased from 865 steps to 722 steps.

Conclusions
ARP may have effectively increased the physical activity of older adults under long-term care by increasing motivation and changing behaviour.
Assessment of dispersion of airborne particles of oral/nasal fluid by high flow nasal cannula therapy
Authors: Jermy M. C. , Spence C. J. T. , Kirton R. , O’Donnell J. F. , Kabaliuk N. , Gaw S. , Hockey H. , Jiang Y. , Zulkhairi Abidin Z. , Dougherty R. L. , Rowe P. , Mahaliyana A. S. , Gibbs A. , Roberts S. A. 
Published: February 2021

Background
Nasal High Flow (NHF) therapy delivers flows of heated humidified gases up to 60 LPM (litres per minute) via a nasal cannula. Particles of oral/nasal fluid released by patients undergoing NHF therapy may pose a cross-infection risk, which is a potential concern for treating COVID-19 patients.

Methods
Liquid particles within the exhaled breath of healthy participants were measured with two protocols: (1) high speed camera imaging and counting exhaled particles under high magnification (6 participants) and (2) measuring the deposition of a chemical marker (riboflavin-5-monophosphate) at a distance of 100 and 500 mm on filter papers through which air was drawn (10 participants). The filter papers were assayed with HPLC. Breathing conditions tested included quiet (resting) breathing and vigorous breathing (which here means nasal snorting, voluntary coughing and voluntary sneezing). Unsupported (natural) breathing and NHF at 30 and 60 LPM were compared.

Results

Imaging: During quiet breathing, no particles were recorded with unsupported breathing or 30 LPM NHF (detection limit for single particles 33 μm). Particles were detected from 2 of 6 participants at 60 LPM quiet breathing at approximately 10% of the rate caused by unsupported vigorous breathing. Unsupported vigorous breathing released the greatest numbers of particles. Vigorous breathing with NHF at 60 LPM, released half the number of particles compared to vigorous breathing without NHF.
Chemical marker tests: No oral/nasal fluid was detected in quiet breathing without NHF (detection limit 0.28 μL/m3). In quiet breathing with NHF at 60 LPM, small quantities were detected in 4 out of 29 quiet breathing tests, not exceeding 17 μL/m3. Vigorous breathing released 200–1000 times more fluid than the quiet breathing with NHF. The quantities detected in vigorous breathing were similar whether using NHF or not.

Conclusion
During quiet breathing, 60 LPM NHF therapy may cause oral/nasal fluid to be released as particles, at levels of tens of μL per cubic metre of air. Vigorous breathing (snort, cough or sneeze) releases 200 to 1000 times more oral/nasal fluid than quiet breathing (p < 0.001 with both imaging and chemical marker methods). During vigorous breathing, 60 LPM NHF therapy caused no statistically significant difference in the quantity of oral/nasal fluid released compared to unsupported breathing. NHF use does not increase the risk of dispersing infectious aerosols above the risk of unsupported vigorous breathing. Standard infection prevention and control measures should apply when dealing with a patient who has an acute respiratory infection, independent of which, if any, respiratory support is being used.

Clinical trial registration
ACTRN12614000924651
Meta-analysis of the correlation between serum uric acid level and carotid intima-media thickness
Authors: Ma Mingzhu , Wang Liangxu , Huang Wenjing , Zhong Xiaoni , Li Longfei , Wang Huan , Peng Bin , Mao Min 
Published: February 2021

ObjectiveRecently, increasing epidemiological evidence has shown that there is a correlation between serum uric acid level (SUA) and carotid intima-media thickness (CIMT). This paper explored the relationship between them through meta-analysis.MethodsPubMed, Cochrane Library, EMBASE, Web of Science and Google Scholar were searched to obtain literature. The keywords used to retrieve the literature were carotid intima thickness, intima-media thickness, carotid atherosclerosis, carotid stenosis, carotid artery, uric acid, blood uric acid, and hyperuricaemia. The retrieval time was from the establishment of the database through July 2020. Stata15.0 and RevMan5.3 software were used for statistical analysis. The standardized mean difference (SMD) and 95% confidence interval (95% CI) were calculated by a random effect model to estimate the correlation. Publication bias was assessed using the Begg and Egger tests. The stability of these results was evaluated using sensitivity analyses.ResultsFifteen studies were included with a total sample size of 11382, including 7597 participants in the high uric acid group and 3785 in the control group, on the basis of the inclusion and exclusion criteria. According to the evaluation of the JBI scale, the literature was of high quality. The average age ranged from 42 to 74. Meta-analysis showed that CIMT in the high uric acid group was significantly higher than that in the control group (SMD = 0.53, 95% CI: [0.38, 0.68]), and the difference was significant (z = 6.98,P< 0.00001). The heterogeneity among the 15 articles was obvious (I2= 89%,P< 0.00001). Subgroup analysis by disease status illustrated a positive relationship between SUA and CIMT in healthy people and people with diseases. SUA was shown to be positively correlated with CIMT in people aged 45–60 years and ≥60 years by subgroup analysis by age. SUA was also found to be positively correlated with CIMT in a population with BMI>24 kg/m2by subgroup analysis by BMI. In addition, subgroup analysis of other risk factors for CIMT, including TC, SBP, DBP, triglycerides, and LDL-C, all showed a positive correlation between SUA and CIMT.ConclusionsThere is a significant correlation between serum uric acid level and carotid intima-media thickness, and a high concentration of serum uric acid is related to carotid artery intima-media thickness.
The influence of patient-centeredness on patient safety perception among inpatients
Authors: Choi Nahee , Kim Jinhee , Kim Hyunlye 
Published: February 2021

PurposeThis study investigated the influence of patient-centeredness on patient safety perception among inpatients, with particular focus on the relationships between subfactors of patient-centeredness and patient safety perception.MethodsData were collected from 122 inpatients in a university hospital from September 24 to October 8, 2019. Patient-centeredness was evaluated using the Patient-Centeredness Assessment Scale; patient safety perception was evaluated using the Korean version of the Patient Safety Perception Scale. Multiple linear regression analysis was conducted using SPSS for Windows 24.0.ResultsAverage patient-centeredness score among inpatients was 77.14 ± 12.64 (range 0–100), and average patient safety perception score was 99.24 ± 15.90 (range 24–120). Patient-centeredness influenced patient safety perception (R2= 70%, F = 27.75,p< .001). With respect to subfactors of patient safety perception, the medical team’s activities to ensure safety was affected by the general treatment process and overall evaluation of patient-centeredness (R2= 54%, F = 13.14,p< .001); patient safety practice was influenced only by the general treatment process (R2= 39%, F = 7.02,p< .001); and trust in the medical system was affected by nurses’ service, the general treatment process, and the hospital environment (R2= 44%, F = 8.49,p< .001).ConclusionsTo enhance patient safety perception, strategies should seek to strengthen patient-centeredness and its related subfactors, particularly the general treatment process, the hospital environment, and nurses’ service.
Sun and beach tourism, senior citizens and accessibility: a study at the coast of the city of João Pessoa, PB
Authors: Melo Priscila Fernandes Carvalho , Brambilla Adriana 
Published: February 2021

The public of senior citizens is growing, due to the greater concern with physical and mental health. Tourism is one of the ways through which this group enjoys their free time, especially the Sun and Beach Tourism, which provides them different kinds of activities. This work aims to answer the following research question: How senior-friendly are the beaches of the João Pessoa coast in terms of accessibility? To meet this research objective, bibliographic, documentary and descriptive research were carried out, and a qualitative analysis was conducted, based on field research, on-site observation and the application of a checklist as the methodological procedures. Through the reports obtained from the on-site observations, it was clear that the urban beaches, i.e. those closest to large urban centers, are more accessible than those further away from the urban centers. However, none of the studied beaches fully met the accessibility criteria outlined in NBR9050/2015. As future contributions, an accessibility guide to the main beaches of João Pessoa will be produced, based on the information obtained, in order to provide information on accessibly for interested parties, including visitors, the public sector and the tourist trade.
On different notions of calibrations for minimal partitions and minimal networks in ℝ2
Authors: Carioni Marcello , Pluda Alessandra 
Published: February 2021

Abstract
Calibrations are a possible tool to validate the minimality of a certain candidate.
They have been introduced in the context
of minimal surfaces
and adapted to the case of the Steiner problem in several variants.
Our goal is to compare the different notions of calibrations
for the Steiner problem and for planar minimal partitions that are already present in the literature.
The paper is then complemented with remarks on the convexification of the problem, on
nonexistence of calibrations and on calibrations in families.
Triharmonic Riemannian submersions from 3-dimensional space forms
Authors: Miura Tomoya , Maeta Shun 
Published: February 2021

Abstract
We show that any triharmonic Riemannian submersion from a 3-dimensional space form into a surface is harmonic. This is an affirmative partial answer to the submersion version of the generalized Chen conjecture. Moreover, a non-existence theorem for f -biharmonic Riemannian submersions is also presented.
Novel Assistive Device for Tomographic Ultrasound Neck Imaging vs. Freehand
Authors: Köhler Marcel , Jeto Gomes Ataide Elmer , Ziegle Jens , Boese Axel , Friebe Michael 
Published: February 2021

Abstract
For assessing clinically relevant structures in the neck area, especially the thyroid, it has been shown that 3D or tomographic ultrasound (3D US or tUS) is able to outperform standard 2D ultrasound [1] and computed tomography [2] for certain diagnostic procedures. However, when using a freehand and unassisted scanning method to acquire a 3D US volume data set in this area overlapping image slices, a variation of the probe angulation or differences in training might lead to unusable scanning results. Based on previous works [3] [4] we propose the design - with subsequent testing - of an assistive device that is able to aid physicians during the tUS scanning process on the neck. To validate the feasibility and efficacy we compared the image quality of both freehand and assisted scanning.
A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography
Authors: Brandt-Wunderlich Christoph , Bonin Franziska , Schmidt Wolfram , Grabow Niels , Schmitz Klaus- Peter , Großmann Swen , Stiehm Michael , Schmitz Klaus-Peter , Siewert Stefan , Öner Alper 
Published: February 2021

Abstract
Optical coherence tomography (OCT) as imaging method is widely used in ophthalmology, oncology and cardiology. For intravascular imaging the OCT is used for pre-interventional as well as post-procedural assessments. Within the current study a test setup for ex vivo determination of the compliance of porcine coronary arteries via OCT is described. Diameter measurements based on OCT imaging were performed during consecutive pressurization of a porcine coronary artery from 40 to 200 mmHg in a physiological environment. The test results indicate that the radial compliance depends on the specific segment of the artery as well as the pressure range considered. The revealed compliance data can be used for numerical simulations of the vascular tissue as well as for optimization of in vitro test setups for pulsatile testing of vascular implants.
EIT based intrathoracic pulsatile impedance measurements during apnea: a case study
Authors: Krueger-Ziolek Sabine , Lovas András , Hawchar Fatime , Laufer Bernhard , Moeller Knut 
Published: February 2021

Abstract
Intrathoracic ventilation related and pulsatile (perfusion) impedance changes can be measured by the noninvasive and radiation-free imaging method Electrical Impedance Tomography (EIT). Ventilation monitoring is still the key research area in EIT, whereby perfusion monitoring gain more and more in interest. However, there are still many unknown influencing factors concerning pulsatile impedance measurements which have to be investigated. Hence, in this observational case study the impact of prolonged apnea periods on pulsatile impedance changes was examined in a patient with suspected brain death undergoing several apnea tests. In addition, the correlation between changes in pulsatile impedance and certain blood gas parameters (carbon dioxide partial pressure, pCO2; oxygen partial pressure, pO2; pH; bicarbonate, HCO3 -) were explored. Results show that the pulsatile impedance signal changes over time during apnea. An increase in the area under the curve (Mean AuC) and the maximum amplitude (Mean Max) of heart beat associated impedance signals was observed (Mean AuC: up to 65 %; Mean Max: up to 57 %). Furthermore, a positive correlation between the increase in impedance and pCO2and HCO3 - was assessed (both: up to 0.99), whereas pO2and pH show a negative correlation (both: up to -0.99). These preliminary results indicate that pulsatile EIT monitoring may be applied to get additional information regarding cardio-pulmonary interactions sustaining diagnosis or treatment of lung diseases.