bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decolonizing the Internet by Decolonizing Ourselves: Challenging Epistemic Injustice through Feminist Practice
Authors: Acey Camille E , Bouterse Siko , Ghoshal Sucheta , Menking Amanda , Sengupta Anasuya , Vrana Adele G 
Published: March 2021

Seventy-five percent of the world’s online population is from the global South, and nearly half is projected to be women. Yet public knowledge on the internet - exemplified by Wikipedia - is primarily constructed by (white) men from western Europe and North America. One in ten Wikipedia editors are estimated to self-identify as female. In other words, the internet of the majority is produced by the minority. But Wikipedia is only one example of the deeply skewed experience of the internet: from the design and architecture of the internet, to the production and reproduction of knowledge on the internet, this globalised “public sphere” not only reflects the structural and representative inequalities of our world, it can, in many ways, amplify and deepen them. Still, the internet’s socio-technical nature can also engender potentially emancipatory processes in which communities on the “margins” of both the physical and virtual worlds can produce and curate their own knowledge online.
Whose Knowledge? is a global, multilingual campaign that aims to make public knowledge and the online experience less white, male, straight, and global North in origin. Using Miranda Fricker’s concept of epistemic injustice and Linda Tuhiwai Smith’s exhortation to decolonize our methodologies, the Whose Knowledge? campaign has supported marginalised communities like Dalits from India and the diaspora, queer activists from Bosnia-Herzegovina, and the Kumeyaay Native American Nation, to begin centering their knowledge online. The authors are feminist scholars, organizers, and technologists, and we describe the practices of decolonizing ourselves in this effort, in particular our approach to embedding feminist and anti-colonial values as we decolonize design, process, and metrics. We offer these possibilities and provocations for thinking further about a future feminist decolonized internet(s).
A case of Carney triad complicated by renal cell carcinoma and a germline SDHA pathogenic variant
Authors: Wurth Rachel , Jha Abhishek , Kamilaris Crystal , Gill Anthony J , Poplawski Nicola , Xekouki Paraskevi , Quezado Martha M , Pacak Karel , Stratakis Constantine A , Hannah-Shmouni Fady 
Published: March 2021

Summary
Succinate dehydrogenase deficiency has been associated with several neoplasias, including renal cell carcinoma (RCC) and those associated with hereditary paraganglioma (PGL)/ pheochromocytoma (PHEO) syndromes, Carney dyad, and Carney triad. Carney triad is a rare multitumoral syndrome characterized by co-existing PGL, gastrointestinal stromal tumor (GIST), and pulmonary chondroma (CHO). We report a case of a 57-year-old male who presented with para-aortic and gastroesophogeal masses, and a right renal superior pole lesion, which were classified as multiple PGLs, a GIST, and a clear cell renal carcinoma, respectively, on pathology following surgical resection. Additionally, a CHO was diagnosed radiologically, although no biopsy was performed. A diagnosis of Carney triad was made. SDHB immunohistochemical staining was negative for the PGL and the GIST, indicating SDH-deficiency. Interestingly, the renal cell carcinoma (RCC) stained positive for both SDHB and SDHA. Subsequent genetic screening of SDH subunit genes revealed a germline inactivating heterozygous SDHA pathogenic variant (c.91 C>T, p.R31X). Loss of heterozygosity was not detected at the tumor level for the RCC, which likely indicated the SDHA variant would not be causative of the RCC, but could still predispose to the development of neoplasias. To the knowledge of the authors this is the first reported case of an SDHA pathogenic variant in a patient with Carney triad complicated by RCC.

Learning points

The succinate dehydrogenase enzyme is encoded by four subunit genes (SDHA, SDHB, SDHC, and SDHD; collectively referred to as SDHx), which have been implicated in several neoplasias and are classified as tumor suppressor genes.

Carney triad is a rare multiple-neoplasia syndrome presenting as an association of PGLs, GISTs, and CHOs.

Carney triad is most commonly associated with hypermethylation of SDHC as demonstrated in tumor tissue, but approximately 10% of cases are due to pathogenic SDHx variants.

Although SDHB pathogenic variants are most commonly reported in SDH-deficient renal cell carcinoma, SDHA disease-causing variants have been reported in rare cases.
Aligning Needs: Integrating Citizen Science Efforts into Schools Through Service Requirements.
Authors: Tsueng Ginger , Kumar Arun , Nanis Steven Max , Su Andrew I 
Published: March 2021

Citizen science is an increasingly valuable tool for both scientists and educators. For researchers, citizen science is a means of more quickly investigating questions which would otherwise be time-consuming and costly to study. For educators, citizen science offers a means to engage students in actual research and improve learning outcomes. Since most citizen science projects are usually designed with research goals in mind, many lack the necessary educator materials for successful integration in a formal science education (FSE) setting. In an ideal world, researchers and educators would build the necessary materials together; however, many researchers lack the time, resources, and networks to create these materials early on in the life of a citizen science project. For resource-poor projects, we propose an intermediate entry point for recruiting from the educational setting: community service or service learning requirements (CSSLRs). Many schools require students to participate in community service or service learning activities in order to graduate. When implemented well, CSSLRs provide students with growth and development opportunities outside the classroom while contributing to the community and other worthwhile causes. However, CSSLRs take time, resources, and effort to implement well. Just as citizen science projects need to establish relationships to transition well into formal science education, schools need to cultivate relationships with community service organizations. Students and educators at schools with CSSLRs where implementation is still a work in progress may be left with a burdensome requirement and inadequate support. With the help of a volunteer fulfilling a CSSLR, we investigated the number of students impacted by CSSLRs set at different levels of government and explored the qualifications needed for citizen science projects to fulfill CSSLRs by examining the explicitly-stated justifications for having CSSLRs, surveying how CSSLRs are verified, and using these qualifications to demonstrate how an online citizen science project, Mark2Cure, could use this information to meet the needs of students fulfilling CSSLRs.
A Survey of Crowdsourcing in Medical Image Analysis
Authors: Ørting Silas Nyboe , Doyle Andrew , Van Hilten Arno , Hirth Matthias , Inel Oana , Madan Christopher R , Mavridis Panagiotis , Spiers Helen , Cheplygina Veronika 
Published: March 2021

Rapid advances in image processing capabilities have been seen across many domains, fostered by the application of machine learning algorithms to "big-data". However, within the realm of medical image analysis, advances have been curtailed, in part, due to the limited availability of large-scale, well-annotated datasets. One of the main reasons for this is the high cost often associated with producing large amounts of high-quality meta-data. Recently, there has been growing interest in the application of crowdsourcing for this purpose; a technique that has proven effective for creating large-scale datasets across a range of disciplines, from computer vision to astrophysics. Despite the growing popularity of this approach, there has not yet been a comprehensive literature review to provide guidance to researchers considering using crowdsourcing methodologies in their own medical imaging analysis. In this survey, we review studies applying crowdsourcing to the analysis of medical images, published prior to July 2018. We identify common approaches, challenges and considerations, providing guidance of utility to researchers adopting this approach. Finally, we discuss future opportunities for development within this emerging domain.
Evaluasi Usability User Interface dan User Experience Aplikasi SAKERNAS PANEL 2018 Badan Pusat Statistik Kota Tangerang Selatan
Authors: Ayuningtias Ashifa , Huda Muhammad Qomarul 
Published: March 2021

Badan Pusat Statistik merupakan lembaga non kementrian dimana lembaga ini bertanggung jawab langsung kepada presiden. Sebelumnya, BPS merupakan Biro Pusat Statistik, yang dibentuk berdasarkan UU Nomor 6 Tahun 1960 tentang Sensus dan UU Nomer 7 Tahun 1960 tentang Statistik. Setiap sistem harus memiliki kualitas yang baik agar mudah digunakan oleh pengguna. Untuk menguji kualitas sistem tersebut maka dilakukan evaluasi sistem dengan menggunakan metode pengujian usability dengan mengobservasi pengguna dengan metode observasi, dilanjutkan dengan metode dan kuesioner Nielsen’s Attributtes Of Usability (NAU). Berdasarkan hasil penelitian yang dilakukan dengan metode observasi Aplikasi SAKERNAS berada pada tingkat ke-3 dari 5 skala atau Cukup, lalu dengan kuesioner NAU dapat disimpulkan bahwa Aplikasi SAKERNAS Badan Pusat Statistik CUKUP dalam memenuhi kelima kategori usability menurut Nielsen Model.
Usulan Keamanan Sistem Informasi pada Penyelenggara Financial Technology (Fintech) Menggunakan Cobit 5 (Studi Kasus: Gandengtangan.org)
Authors: Nurkholis Oki , Fitroh Fitroh Fitroh , Rustamaji Eri 
Published: March 2021

Gandengtangan.org adalah salah satu perusahaan startup di bidang financial technology (fintech) yang ada di Indonesia. Gandengtangan.org menyediakan layanan pengumpulan pinjaman (crowdlending) untuk para pelaku usaha sosial atau UMKM yang ada di Indonesia. Beberapa masalah yang muncul pada penelitian ini di antaranya: (1) kerentanan penggunaan internet terutama sektor finansial yang menjadi target serangan nomor 2 terbanyak. (2) Otoritas Jasa Keuangan (OJK) juga mewajibkan untuk setiap penyelenggara fintech di Indonesia agar dapat memenuhi standardisasi mengenai keamanan informasi pada perusahaannya. (3) Belum pernah dilakukaannya evaluasi terhadap keamanan sistem informasi di Gandengtangan. (4) Terjadinya 4 kasus keamanan informasi: satu kasus terkait phising, dua kasus tentang integrasi data, dan satu kasus terkait ssl (secure socket layer). Hal ini menunjukan keamanan informasi menjadi hal yang perlu mendapatkan perhatian penting pada Gandengtangan.org. Metode penilaian yang digunakan adalah perpaduan antara Process Assessment Model (PAM) dengan COBIT 5 Life cycle. Dipilih 5 domain yang berhubungan dengan keamanan pada COBIT 5 yakni, EDM03 (Ensure Risk Optimisation), APO12 (Manage Risk), APO13 (Manage Security), BAI06 (Manage Changes), dan DSS05 (Manage Security Services). Penelitian ini menghasilkan usulan keamanan informasi yang menjadi panduan Gandengtangan.org untuk mengantisipasi kerentanan keamanan pada bisnisnya dan untuk memenuhi persyaratan dari OJK.
Adatok II. Lajos magyar király páncélos ábrázolásaihoz
Authors: Papp Júlia 
Published: March 2021

Most of the posthumous portraits of Louis II, who died in the battle of Mohács in 1526, show him in armour. In some pictures he is wearing fictitious armour, but in other portraits he is clad in the armour which until 1939 was believed to had once been his, but actually had been made in 1533 for the Polish king Sigismund II Augustus and is currently kept in the Hungarian National Museum. The author of the study has examined the latter group of artworks. She describes the armours of Louis II, some only mentioned in archival sources or historical works. Some items that can certainly or presumably be attributed to him are kept in museums abroad. The first paintings in which Louis II is wearing the gilded ornamental armour were painted by István Dorffmeister in the mid-1780s. Since at that time the armour was on display in one of the gala rooms fitted out in Vienna’s Kaiserliches Zeughaus in the 1760s, the study discusses the history of the imperial armour and weapon collections and the conception of the arms exhibition in the Zeughaus at that time. After the demolition of the Zeughaus in 1856, the armour was transferred, together with the rest of the imperial collection of armours and weapons, to the war museum wing of the newly built Arsenal. The armour was presented by the Austrian catalogues of the museum as belonging to Louis II, and some items had illustrations added to them. The armour was introduced in Pest in 1876 at a historical exhibition for charitable purposes, and later in 1896 at the Millennial Exhibition. The Hungarian press also devoted articles to it, and several scholarly papers were written about the armour.The prototypes for some of the 19th century artworks depicting Louis II in the Viennese armour – most of them local monuments preserving the memory of the battle – were István Dorffmeister’s paintings. His battle scene showing the death of Louis II appears in a sketch of an unrealized monument, dated 1846; in the picture painted on metal that adorned the monument in Mohács in the 1860s and on the bronze relief replacing it in the late 1890s. The antecedents to another group of representations must have been the 19th century Austrian and Hungarian descriptions and illustrations of the armour attributed to Louis II. The ruler wears this armour in several book illustrations and on the statue by Ferenc Vasadi on the Danubian facade of the Hungarian Parliament building.Although these artworks presenting Louis II in Sigismund II Augustus’ armour do not satisfy the iconographic criteria of historical authenticity, they were up-to-date for their time, for instead of depicting the fictitious, often waywardly fantastic armours of earlier centuries, they presented the portrayed person in an existing armour made in his own era, that is, with a historically authentic appearance.
Lechner Ödön rajzai a szegedi városházához
Authors: Váraljai Anna 
Published: March 2021

The paper is about the set of drawings and documents by Ödön Lechner and Gyula Pártos for the Town-hall of Szeged dated to 1881–1883 (Hungarian National Archives, Csongrád-Csanád County Archives, Szeged [MNL CSML], Collection of Building Plans and Documents of the Municipality of Szeged, marked Lecher Ödön, Pártos Gyula: A Szegedi Városházhoz készített tervek, rajzok és iratok, [Plans, drawings and documents for the Szeged Town-hall], XV.2b. 45. d.-49.d). The elaborated theme includes ground-plans, rosette, baluster and skylight plans, detail plans of staircase and main cornice, plan of the roof of the main staircase, 37 drawings of ornamental sculpture, window pillars, window frames and rail chains, painter’s stencils signed by Ödön Lechner, two façade versions, tower detail, details of the main portal, drawings of the vault around the clock, of the ornaments of room doors and cornice elements. The building logbooks, list of submissions to the competition with code-names and the contracts signed with the building contractors are also valuable sources.In addition to eighty drawings of diverse sizes and techniques, the collection includes the construction documents, accounts, correspondence, building logbooks, planning competition calls, and a colour plan for the tiling of the Szeged Town-hall now in the Architectural Collection of the Kiscelli Museum of the Budapest History Museum (inv.no. 117). I evaluate the drawings both within the conception of an architectural work and also as separate graphic sheets, and try to describe their background in terms of the history of architecture, art and ideas.I am led to conclude that the Szeged Town-hall was the first project to manifest Lechner’s ambition to lay the groundworks of a national architecture based on the more abstracted and universal basic forms of folk art but keeping abreast of European tendencies. The drawings are invaluable in that they add more information to the chronology of Lechner’s artistic career and lend stress to the fact that folklore and local history researches, the intellectual approach, the synthesis of local and international achievements, a thorough knowledge of the history of ceramics, the redefinition of traditions played at least as important roles in creating the concept of a building as individual intention and creative imagination.The paper was supported by the Ernő Kállai Art Historical Research Grant.
Syncope mint a SARS-CoV-2-fertőzés egyedüli tünete
Authors: Arabadzisz Hrisula , Tako Katalin , Tomcsányi János 
Published: March 2021

Összefoglaló. Egy 61 éves, SARS-CoV-2-fertőzött, traumás syncopés
nőbeteg rosszullétének hátterében orthostaticus hypotonia igazolódott. A
vírusfertőzés megszűnése után az orthostaticus hypotonia megszűnt, de a
posturalis tachycardia fennmaradt. A syncopénak egyéb okát kimutatni nem tudtuk.
A SARS-CoV-2-fertőzésnek egyéb tünete, illetve szervi manifesztációja nem volt.
Tudomásunk szerint ez az első eset, amelyben a SARS-CoV-2-infekció egyedüli
tünete a syncope. Orv Hetil. 2021; 162(7): 243–245.
Summary. Orthostatic hypotension was demonstrated in the background
of malaise in a 61-year-old SARS-CoV-2 infected female traumatic syncope. After
cessation of the virus infection, orthostatic hypotension resolved, but postural
tachycardia persisted. No other cause of syncope could be detected. There were
no other symptoms or organ manifestations of SARS-CoC-2 infection. To our
knowledge, this is the first case where the only symptom of SARS-CoV-2 virus
infection is syncope. Orv Hetil. 2021; 162(7): 243–245.
Anti-CD20 mAb-Induced B Cell Apoptosis Generates T Cell Regulation of Experimental Myeloperoxidase ANCA-Associated Vasculitis
Authors: Gan Poh-Yi , Dick Jonathan , O’Sullivan Kim M. , Oudin Virginie , Cao Le Anne , Koo Yuk Cheong Daniel , Shim Raymond , Alikhan Maliha , Kitching A. Richard , Ooi Joshua D. , Holdsworth Stephen R. 
Published: March 2021

Significance Statement
Myeloperoxidase ANCA-associated vasculitis (MPO-AAV) is an important cause of renal failure. Although rituximab has been shown to effectively attenuate MPO-AAV, its underlying mechanism of action beyond depletion of CD20+ B cells producing ANCA is unknown. Administration of mouse anti-CD20 mAb to a murine anti-MPO GN mouse model reduced not only serum MPO-ANCA but also, T cell responses. Interestingly, anti-CD20 mAb treatment increased the frequency and functional potency of Tregs. Administration of anti-CD20 mAb rendered B cells apoptotic and resulted in the attenuation of anti-MPO autoimmunity and GN. This highlights a novel pathway by which anti-CD20 mAb therapy may attenuate T cell–mediated autoimmunity.

Background
Myeloperoxidase ANCA-associated vasculitis is a major cause of ESKD. Efficacy of anti-CD20 mAb treatment was tested in a mouse model of the disease.

Methods
MPO immunization induced anti-MPO autoimmunity, and a subnephritogenic dose of sheep anti-mouse GBM globulin triggered GN.

Results
Anti-CD20 mAb treatment increased the numbers and immunomodulatory capacity of MPO-specific T regulatory cells (Tregs) and attenuated T cell–mediated and humoral anti-MPO autoimmunity and GN. Disabling of Tregs negated the therapeutic benefit of anti-CD20 treatment. The mechanism of enhancement of Treg activity could be attributed to anti-CD20 mAb effects on inducing B cell apoptosis. Administering anti-CD20 mAb-induced apoptotic splenocytes to mice developing anti-MPO GN was as effective as anti-CD20 mAb treatment in inducing Tregs and attenuating both anti-MPO autoimmunity and GN. A nonredundant role for splenic macrophages in mediating the anti-CD20 mAb-induced immunomodulation was demonstrated by showing that administration of anti-CD20 mAb ex vivo–induced apoptotic splenocytes to unmanipulated mice attenuated autoimmunity and GN, whereas deletion of splenic marginal zone macrophages prevented anti-CD20 mAb-induced immunomodulation and treatment efficacy. Six days after administering anti-CD20 mAb to mice with murine anti-MPO GN, cell-mediated anti-MPO responses and GN were attenuated, and Tregs were enhanced, but ANCA levels were unchanged, suggesting humoral autoimmunity was redundant at this time point.

Conclusions
Collectively, these data suggest that, as well as reducing humoral autoimmunity, anti-CD20 mAb more rapidly induces protective anti-MPO Treg-mediated immunomodulation by splenic processing of anti-CD20–induced apoptotic B cells.
Методика получения серебросодержащего сорбента на основе бентонита для фиксации соединений радиоиода
Authors: Tyupina Ekaterina A. , Pryadko Artem V. , Merkuskin Aleksey O. 
Published: March 2021

Работа относится к области радиоэкологии и посвящена защите окружающей среды от радиоактивных изотопов иода. В радиоактивных отходах (РАО) иод находится в анионных формах I‑ и IO3‑, в этих формах возможна миграция радиоиода в окружающую среду. Системы инженерных барьеров безопасности в хранилищах РАО должны предотвращать попадание радионуклидов за пределы хранилища. Их предполагается сооружать из компактированных бентонитовых глин, обладающих высокими водоизоляционными и катионообменными свойствами, но не сорбирующими анионы. Следовательно, требуется модификация бентонитов для придания им способности сорбировать иод, перспективным вариантом которой является нанесение серебра с последующим переводом его в соединения, подходящие для фиксации любых подвижных форм радиоиода. Существует ряд методик нанесения серебра на различные материалы, однако, они отличаются трудоёмкостью или не позволяют равномерно наносить серебро на пористые материалы.
В данной работе навеску нитрата серебра растворяли в дистиллированной воде и вносили двукратный мольный избыток гидроксида натрия. Выпавший осадок оксида серебра растворяли, добавляя по каплям концентрированный раствор аммиака. Затем в раствор добавляли гексаметилентетрамин (ГМТА). Объём готового раствора был равен водоёмкости навески бентонита с небольшим избытком. Раствор вносили в бюкс с известной навеской бентонита и оставляли на 25 часов для полного набухания материала. Затем бюкс выдерживали в течение 24 часов в сушильном шкафу при 90°C. При повышенной температуре происходил термический гидролиз ГМТА с выделением формальдегида, который восстанавливал серебро до металла. Для определения количества нанесённого серебра бентонит обрабатывали 2 см3 3М азотной кислоты и титровали полученный раствор стандартизированным раствором роданида аммония в присутствии ионов Fe3+. Согласно результатам титрования, выход восстановленного серебра, осаждённого на поверхность бентонита составил 95% от внесённого количества. Электронную микроскопию и энергодифракционную спектроскопию (ЭДС) проводили на сканирующем электронном микроскопе TESCAN VEGA 3. На ЭДС-спектре присутствует отчётливый пик на энергии 2.984 кЭв, свидетельствующий о присутствии серебра на поверхности частиц исследованного образца, которое как показало рентгеновское картирование, распределено по поверхности бентонита равномерно.
Разработана эффективная методика равномерного нанесения металлического серебра на бентонит с высоким выходом (95%) для последующего перевода его в соединения, подходящие для фиксации любых подвижных форм радиоиода, например, растворимой анионной формы радиоиода в хранилищах РАО.