bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correction factor between two calcitonin assays: DiaSorin LiaisonXL and Cobas E601
Authors: Baetu Mara , Draghici Alexandru , Padure Adriana , Bucur Stefana , Caragheorgheopol Andra , Badiu Corin 
Published: August 2021

Abstract

Introduction: Calcitonin measurement is important for the diagnosis and monitoring of medullary thyroid carcinoma. Unfortunately, in clinical practice, different detection systems assays are used in the follow-up of the patients, which can be misleading.

Objective: To identify the correction factor for calcitonin measurement on two different immunoanalysers: DiaSorin-LiaisonXL (immunochemiluminescence) and CobasE601 (electro-immunochemiluminescence).

Methods: We selected 89 registered CT samples (28-from men; 61-from women), that were analysed on CobasE601 with reported values between 0.5 pg/ml and 2812 pg/ml (128.5±513.98). These CT samples were selected randomly to cover as wide a range of values as possible, and represented either basal CT (n=38) or selected from CT stimulation tests (n=51). Samples were evaluated subsequently on DiaSorin-LiaisonXL. All patients gave their informed consent.

Results: Between the two assays a segmented linear correlation was noted. We identified the following general linear regression equation: 1.108x+19.337 (p<0.05). The bias increased at high calcitonin values. Therefore, for a better accuracy we analysed the regression equation segmentally. A statistic difference (p<0.05) was noted for CT values ranged between 350-2600 pg/ml (n=31) on DiaSorin-LiaisonXL, for which the linear regression equation for CobasE601 becomes 1.009x+169.796.

Conclusions: Calcitonin correction factors are highly important in the dynamic follow up of a patient suffering from medullary thyroid carcinoma when different detection systems assays are used to determine calcitonin. We identified the correction factors for calcitonin determination between two different frequently used chemiluminescence immunoanalysers: DiaSorin-LiaisonXL and CobasE601. However, it is strongly advisable to use the same analyser in order to establish biochemical evolution of calcitonin.
Genetic Diagnostic Approaches in Familial Hypercholesterolemia Evaluation
Authors: Moldovan Valeriu , Bănescu Claudia , Dobreanu Minodora 
Published: August 2021

Abstract
Familial hypercholesterolemia (FH) manifested as atherosclerosis is a major cause of coronary heart disease. Different scoring systems based on clinical and paraclinical data are currently used, but the FH diagnosis should be made only in the presence of the causative genetic defect. In the present study, 12 symptomatic (previously diagnosed with atherosclerosis) and asymptomatic family members were investigated. Serum lipids were measured using commercial reagents. A genetic investigation was performed by Sanger sequencing using commercial reagents and custom primers, while copy number variations and a selected set of 40 point mutations were evaluated using in vitro diagnostic medical devices. For the investigated patients, serum lipids were within the reference range, due to the fact that the subjects were following lipid-lowering therapy, and smoking was the only identifiable additional risk factor. Four benign exon variants and three intron variants situated within the low-density lipoprotein cholesterol receptor gene were identified by Sanger sequencing. No copy number variations and none of the 40 investigated point mutations were determined. Although independently considered benign, the combined effect of the identified genetic conditions could be pathogenic under the influence of additional risk factors. Even in the presence of a diagnosis made using clinical scores, the molecular diagnosis is often challenging, attesting to the complexity of FH genetic etiology.
Chemical Composition and Biological Activity of Trapa Natans L.
Authors: Corovic Rosa Cukic , Bradic Jovana , Tomovic Marina , Dabanovic Vera , Jakovljevic Vladimir , Zarkovic Gala , Rogac Zeljka 
Published: August 2021

Abstract
Trapa natans L., water chestnut (indian name singada, montenegrin name kasaronja) belonging to Trapaceae family is annual aquatic floating herb native to Asia but widely distributed in the Europe and in North America. The presence of two species, Trapa natans L. and Trapa longicarpa M.Jank. ssp. scutarensis M.Jank has been confirmed on the Skadar lake in Montenegro. Trapa natans is a plant demonstrating promising pharmacological activity mostly due to the presence of its constituens, phenols and flavonoids, showed hepatoprotective potential, antioxidant, anti-inflammatory, antidiabetic, antifungal and in vitro antimicrobial activity.
In the Tortuous Shadows of Ethnic Policies: Two Case Studies of Chinese Cultural Heritage in Indonesia and Malaysia
Authors: Voss Gabriella 
Published: August 2021

Abstract
Concurrent with the inception of the nation states of Indonesia and Malaysia in the middle of the twentieth century, ethnic policies were put into practice to destroy the Chinese cultural heritage that had hitherto been regarded as a vital part of the region’s heterogeneous cultural landscapes. Chinese language, organisations, and religious practices were banned, and architecture and artefacts with Chinese symbols or insignia either looted or destroyed. To what extent have these discriminatory agendas further influenced and shaped contemporary Chinese cultural heritage discourse? To answer this question this article starts with an introduction to the anti-Chinese agenda from Independence onwards, which is followed by two case studies from the field of cultural heritage: the organisation Boen Hian Tong in Semarang on Java in Indonesia, and the NGO Penang Heritage Trust in Malaysia. The research is based on fieldwork carried out in Indonesia and Malaysia in 2014–2015.
Kyara in Japanese Religious Spaces
Authors: Saikia Alisha 
Published: August 2021

Abstract
Mascots in Japan are called kyara. They are utilised by almost all organisations, institutions, and administrative divisions and are accepted, embraced, and consumed by people of all walks of life, making them immensely popular. Although constituting an element of Japanese popular culture, they are also embedded in certain religious spaces in Japan, making them an interesting topic of research. This article will examine the reason behind the embeddedness of kyara in certain religious spaces in Japan and their impact on the practice of religion in those spaces.
Agenesis of corpus callosum, severe developmental delay, recurrent infections, and cutaneous hypopigmentation: a case of Vici syndrome
Authors: Rauf Fatima , -Haq Mansoor-ul , Sidra Rauf 
Published: August 2021

Background:
Vici syndrome is a rare, autosomal recessive multisystem disorder, first described in 1988 by Dionisi-Vici. This syndrome is characterized by corpus callosum agenesis, oculocutaneous hypopigmentation, cataracts, immunodeficiency, and cardiomyopathy with additional variable multisystem manifestations.

Case Presentation:
We present a case of a 2-month-old infant, born preterm via Spontaneous vaginal delivery (SVD). He presented with fever, fits, and developmental delay. His weight and head circumference were below the third percentile for age and sex. In addition, he had hypopigmented skin and hair, a long philtrum, micrognathia, and high-arched palate. He had generalized hypotonia and hyporeflexia and his eyes showed horizontal nystagmus. His brain magnetic resonance imaging showed agenesis of corpus callosum, colpocephaly, and periventricular necrosis of white matter. He was admitted as a case of Vici syndrome and was treated for infections and seizures. He presented to emergency afterward as well for sepsis and eventually died of cardiopulmonary arrest at an age of 6 months.

Conclusion:
Vici syndrome is a rare disease and around 80 cases have been reported so far. This is a first reported case in Pakistan. It has variable presentation but agenesis of corpus callosum, recurrent infections, microcephaly, cardiomyopathy, cataracts, seizures, developmental delay, and hypopigmentation remain the most common features.
A Decision Tree-Aware Genetic Algorithm for Botnet Detection
Authors: Alhijaj Thurayaa B. , Hameed Sarab M. , Attea Bara'a A. 
Published: August 2021

In this paper, the botnet detection problem is defined as a feature selection problem and the genetic algorithm (GA) is used to search for the best significant combination of features from the entire search space of set of features. Furthermore, the Decision Tree (DT) classifier is used as an objective function to direct the ability of the proposed GA to locate the combination of features that can correctly classify the activities into normal traffics and botnet attacks. Two datasets namely the UNSW-NB15 and the Canadian Institute for Cybersecurity Intrusion Detection System 2017 (CICIDS2017), are used as evaluation datasets. The results reveal that the proposed DT-aware GA can effectively find the relevant features from the whole features set. Thus, it obtains efficient botnet detection results in terms of F-score, precision, detection rate, and number of relevant features, when compared with DT alone.
Enhancement of Spectrum Sensing Performance via Cooperative Cognitive Radio ‎Networks at Low SNR
Authors: Kotb Kotb A. , Shalaby Ahmed S. , Yahya Ahmed 
Published: August 2021

The inefficient use of spectrum is the key subject to overcome the upcoming spectrum crunch issue. This paper presents a study of performance of cooperative cognitive network via hard combining of decision fusion schemes. Simulation results presented different cooperative hard decision fusion schemes for cognitive network. The hard-decision fusion schemes provided different discriminations for detection levels. They also produced small values of Miss-Detection Probability at different values of Probability of False Alarm and adaptive threshold levels. The sensing performance was investigated under the influence of channel condition for proper operating conditions. An increase in the detection performance was achieved for cognitive users (secondary users) of the authorized unused dynamic spectrum holes (primary users) while operating in a very low signal-to-noise ratio with the proper condition of minimum total error rate.
الإطار القانوني لعقد استثمار الطاقة الكهربائية (عقد استثمار الطاقة الكهربائية بين حكومة اقليم كوردستان وشركة ماس العالمية نموذجا)
Authors: S. Ismail Heval , S. Othman Omed 
Published: August 2021

يعد عقد استثمار الطاقة الكهربائية من العقود المهمة في الوقت الحاضر، وذلك لكونه من العقود ذات الصلة بالتنمية الاقتصادية من جانب ومن جانب اخر لها علاقة بالمرافق الخدمية التي لا يمكن الاستغناء عنها، وعليه تسعى الدول النامية التي تعجز عن توفير الطاقة الكهربائية الى القطاع الخاص من خلال ابرام عقود مع المستثمرين الاجانب المختصين في هذا المجال، مع توفير بيئة استثمارية ملائمة لهم، وعادة يفضل المستثمر الاجنبي الى التعاقد مع الدولة بأسلوب عقد B.O.O. (البناء، التشغيل، والتمليك) لان مثل هذا الاسلوب لاتنتقل ملكية المشروع الى الدولة بعد انتهاء من مدة العقد، ونظراً لكون الدولة طرفأ في العقد والطرف الاخر شخص اجنبي فقد اختلف الفقه حول تحديد الطبيعة القانونية لمثل هذا العقد فمنهم من يرى بان مثل هذه العقود هي عقود ادارية ويخضع احكامه الى القانون العام، بينما هناك اتجاه حديث يستبعد مثل هذه العقود للقانون العام ويعطيه الطبيعة الخاصة، كما ان لهذه العقود لها خصوصياتها من حيث الالتزامات المترتبة عليها والالية المختارة لتسوية المنازعات الناشئة عنه. وعليه قامت حكومة اقليم كوردستان بالتعاقد وفق ذلك الاسلوب مع احدى الشركات الاجنبية لتقوم هذا الاخير بتجهيز الطاقة الكهربائية لوزارة الكهرباء ليتسنى هذا الاخير بتجهيزها الى المواطنيين.
التكاليف الاقتصادية للإرهاب وأثره في النمو الاقتصادي لمجموعة من دول مختارة للمدة (2004-2018)
Authors: M. Saeed Hashim , S. Yousif Akram 
Published: August 2021

تناقش الدراسة أهم الدوافع الاقتصادية للإرهاب وتكاليفها المباشرة وغير المباشرة واثرها في النمو الاقتصادي لمجموعة من الدول المختارة في اسيا وافريقيا خلال المدة (2004-2018) وذلك باستخدام طريقة البيانات المدمجة (Panel Data) ضمن النموذج القياسي المقدر لتحليل وتقدير اثر الإرهاب في النمو الاقتصادي، وبالاعتماد على بعض المتغيرات الاقتصادية لهذه الدول منها نسبة الانفاق العسكري من أجمالي الانفاق العام وصافي تدفقات الاستثمار الأجنبي المباشر الى البلد، ونسبة إيرادات القطاع السياحي من إجمالي الإيرادات العامة، بالإضافة إلى متغير نسبة الصادرات الى الناتج المحلي الإجمالي للدلالة على مدى الانفتاح الاقتصادي للدول المختارة وتأثير كل هذه المتغيرات في نصيب الفرد من الناتج المحلي الإجمالي، كما تبحث الدراسة في الاثار الاقتصادية المترتبة على هذه الظاهرة وسبل مواجهتها من المنظور الاقتصادي، وتبين من نتائج الدراسة ان العلاقة بين الإرهاب والنمو الاقتصادي علاقة سلبية بحيث كلما ازدادت حدة العنف والحروب أدى إلى انخفاض معدلات النمو الاقتصادي لدول مختارة ضمن عينة الدراسة.
PERANCANGAN IDENTITAS VISUAL REBRANDING CITRA PERUSAHAAN CEMARA CERAMICS (Design of Cemara Ceramics' Visual Rebranding Identity)
Authors: Marhendra Anak Agung Ngurah Gede , Budiwaspada Agung Eko , Nilotama Sangayu Ketut Laksemi 
Published: August 2021

<p><strong><em>Abstract</em></strong></p><p><strong><em>Desig</em></strong><strong><em>n of Cemara Ceramics' Visual Rebranding Identity </em></strong><em>aim</em><em>s to produce a concept strategy and visual rebranding of the Cemara Ceramics company and produce a Cemara Ceramics rebranding visual identity design in order to encourage the creation of a new identity image. The</em></p><p><em>metho</em><em>d in this design uses a 5-stage Design Thinking approach, namely Empathize, Define,</em></p><p><em>Ideate</em><em>, Prototype and Test. The result achieved is the design of the new Cemara Ceramics corporate identity. With the use of the design thinking method in this research, various problems related to the company image of Cemara Ceramics can be found. The core problem obtained is how to design a strategy and concept of visual identity rebranding to encourage the creation of a new corporate image of Cemara Ceramics.</em></p><p><strong><em>Keywords</em></strong><em>: Visual Rebranding Identity, concept strategy, Design Thinking</em></p><p> </p><h1>Abstrak</h1><h3>Perancangan Identitas Visual Rebranding Citra Perusahaan Cemara Ceramics ini bertujuan</h3><p><em>untu</em><em>k menghasilkan strategi konsep dan visual rebranding perusahaan Cemara Ceramics serta menghasilkan rancangan identitas visual rebranding Cemara Ceramics dalam rangka mendorong terciptanya citra identitas yang baru. Metode dalam perancangan ini menggunakan pendekatan 5 tahapan Design Thinking yaitu Empathize, Define, Ideate, Prototype dan Test. Hasil yang dicapai yaitu rancangan corporate identity Cemara Ceramics yang baru. Dengan adanya penggunaan metode design thinking pada penelitian ini dapat menemukan berbagai permasalahan terkait citra perusahaan Cemara Ceramics. Permasalahan inti yang didapat yaitu mengenai bagaimana merancang strategi dan konsep identitas visual rebranding untuk mendorong terciptanya citra baru perusahaan Cemara Ceramics.</em></p><p><strong>Kat</strong><strong>a kunci: </strong><em>Identita</em><em>s Visual Rebranding</em>, <em>strateg</em><em>i konsep dan visual, Design Thinking</em></p>
A numerical study of the working process in the chamber of a thruster rocket engine based on oxygen-hydrogen fuel
Authors: Салич В.Л. 
Published: August 2021

Применение численного моделирования смесеобразования и горения в процессе проектирования камеры кислородно-водородного ракетного двигателя малой тяги позволило в короткие сроки получить конструкцию, обеспечивающую высокие энергетические характеристики, что впоследствии было подтверждено экспериментально. В настоящей статье представлены результаты расчетов, полученные при использовании различных моделей турбулентности (моделей на основе гипотезы турбулентной вязкости и рейнольдсовых напряжений) и моделей химического взаимодействия (моделей тонкого фронта пламени и диссипации вихря), а также результаты, полученные на различных типах и размерностях расчетной сетки. В результате исследований установлено, что тип сетки не оказывает существенного влияния на результаты моделирования; предпочтения отданы модели рейнольдсовых напряжений и модели диссипации вихря. Приводятся сопоставления характеристик камеры на различных режимах работы, полученных экспериментально и по результатам моделирования.
The application of numerical simulation of mixture formation and combustion during the design of the chamber of a thruster rocket engine based on oxygen-hydrogen fuel allows one to rapidly develop a construction with high-power characteristics, which was later confirmed experimentally. This paper considers the results of computations obtained by using the
turbulence models based on the hypothesis of turbulent viscosity and Reynolds stresses and using the chemical interaction models (the models of a thin flame front and the eddy dissipation). The numerical results obtained on the basis of computational grids of various types and dimensions are discussed. It is shown that the grid type has little effect on the simulation results and that the Reynolds stress model and the eddy dissipation model are preferable. The characteristics of the chamber obtained experimentally and numerically for various modes of operation are compared.
Balanced Nutrition and Nutrition Status of Schoolchildren in Rural Areas of Ogan Komering Ilir District South Sumatra Indonesia
Authors: Febry Fatmalina , Rahmiwati Anita , Arinda Ditia Fitri 
Published: August 2021

To support the growth and development of children and adolescents, a balanced nutritious diet is required. Indonesia issues a balanced nutrition guideline as the government's effort to overcome various nutritional problems in Indonesia. This study aimed to evaluate the relationship among four pillars of balanced nutrition, namely eating a variety of foods, monitoring body weight, hygiene and healthy living habits and physical activity with nutritional status in school children. This study used a cross-sectional method which was conducted in elementary schools in rural areas with a number of sample of 80 schoolchildren with purposive sampling technique. The data were taken directly by means of interviews and anthropometric measurements. Based on the results of the study, there was a relationship between various foods and physical activity with nutritional status, while for the clean and healthy living habits and monitoring of body weight there was no relationship to the nutritional status of school children. There was a relationship between diverse foods and physical activity and nutritional status of schoolchildren in rural areas of Ogan Komering Ilir District.
The evolving appreciation of projects – a study of stakeholder dynamics
Authors:   , La Van 
Published: August 2021

<p><b>Even though many project management techniques and methods have been developed and established, project managers and practitioners still find themselves unprepared and overwhelmed by the complexity and changing nature of stakeholder thinking and behaviour. The literature of stakeholder management and stakeholders in projects indicates that this complexity can be explained by the dynamics, complex interactions, and individual differences of project stakeholders. Thus, stakeholder perception and their social networks are dynamic and influence each other during project implementation. Both of them are also affected by the individual characteristics of stakeholders, which are linked to their past experience and background. However, while studies have focused on stakeholder dynamics as influenced by their social networks, very few of them focus on these dynamics as influenced by both the social networks and individual characteristics of stakeholders. This research addresses this gap by considering both aspects in the analysis of stakeholder dynamics or in other words, stakeholder dynamics at individual levels.	The research follows the social constructionist paradigm and uses Vickers’ concept of appreciative systems as the theoretical lens. Through this lens, the above dynamics of stakeholder perception are described as the dynamics of their appreciation of projects as influenced by their standards and perceptions of events and ideas. The Repertory Grid Technique was the main data collection and analysis method. Data were collected from 47 interviews with ten participants who were each involved with one of three university accreditation projects, two in Vietnam and one in New Zealand. Data analysis consisted of the principal component analysis of repertory grids to identify the changes in standards and appreciation, the integration of these changes with the participants’ perceptions of events and ideas through the lens of Vickers’ concept, and the identification of the common themes. </b></p>
<p>	The research found that stakeholders may change the interactions that they focus on and their levels of concern about these interactions during project implementation. The drivers of these dynamics are the changes in the standards and social networks of stakeholders. A framework is proposed to summarise these dynamics and drivers. Overall, the research provides further understanding of the complex dynamics of stakeholders as influenced by their individual characteristics. Based on this understanding, the research identifies empirical strategies for project managers to understand and address stakeholders at individual levels. Finally, the research suggests potential directions for future research of stakeholder dynamics in projects.</p>
The evolving appreciation of projects – a study of stakeholder dynamics
Authors: La Van 
Published: August 2021

<p><b>Even though many project management techniques and methods have been developed and established, project managers and practitioners still find themselves unprepared and overwhelmed by the complexity and changing nature of stakeholder thinking and behaviour. The literature of stakeholder management and stakeholders in projects indicates that this complexity can be explained by the dynamics, complex interactions, and individual differences of project stakeholders. Thus, stakeholder perception and their social networks are dynamic and influence each other during project implementation. Both of them are also affected by the individual characteristics of stakeholders, which are linked to their past experience and background. However, while studies have focused on stakeholder dynamics as influenced by their social networks, very few of them focus on these dynamics as influenced by both the social networks and individual characteristics of stakeholders. This research addresses this gap by considering both aspects in the analysis of stakeholder dynamics or in other words, stakeholder dynamics at individual levels.	The research follows the social constructionist paradigm and uses Vickers’ concept of appreciative systems as the theoretical lens. Through this lens, the above dynamics of stakeholder perception are described as the dynamics of their appreciation of projects as influenced by their standards and perceptions of events and ideas. The Repertory Grid Technique was the main data collection and analysis method. Data were collected from 47 interviews with ten participants who were each involved with one of three university accreditation projects, two in Vietnam and one in New Zealand. Data analysis consisted of the principal component analysis of repertory grids to identify the changes in standards and appreciation, the integration of these changes with the participants’ perceptions of events and ideas through the lens of Vickers’ concept, and the identification of the common themes. </b></p>
<p>	The research found that stakeholders may change the interactions that they focus on and their levels of concern about these interactions during project implementation. The drivers of these dynamics are the changes in the standards and social networks of stakeholders. A framework is proposed to summarise these dynamics and drivers. Overall, the research provides further understanding of the complex dynamics of stakeholders as influenced by their individual characteristics. Based on this understanding, the research identifies empirical strategies for project managers to understand and address stakeholders at individual levels. Finally, the research suggests potential directions for future research of stakeholder dynamics in projects.</p>