bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trends of CO and NO2 Pollutants Change in Iran during Covid-19 Pandemic using Time-Series Sentinel-5 Images in Google Earth Engine
Authors: Shami Siavash , Ranjgar Babak , Azar Mahdi Khoshlahjeh , Moghimi Armin , Sabetghadam Samaneh , Amani Meisam 
Published: August 2021

Abstract
The first cases of Covid-19 in Iran were reported shortly after the disease outbreak in Wuhan, China. The end of the Persian year and the beginning of the Nowruz holidays in the following year (March 2020) coincided with its global pandemic, which led to quarantine and lockdown in the country. Many studies have shown that with the spread of this disease and the decline of industrial activities, environmental pollutants were drastically reduced. Among these pollutants, Nitrogen Dioxide (NO2) and Carbon Monoxide (CO) are widely caused by anthropogenic and industrial activities. In this study, the changes of these pollutants in Iran and its four metropolises (i.e., Tehran, Mashhad, Isfahan, and Tabriz) in three time periods from March 11 to April 8 of 2019, 2020, and 2021 were investigated. To this end, time-series of the Sentinel-5P TROPOMI and in-situ data within the Google Earth Engine (GEE) cloud-based platform were employed. It was observed that the results obtained from the satellite data were in agreement with the in-situ data (average correlation coefficient = 0.7). Moreover, the results showed that the concentration of NO2 and CO pollutants in 2020 (the first year of the Covid-19 pandemic) was 5% lower than in 2019, indicating the observance of quarantine rules as well as people’s initial fear of the Coronavirus. Contrarily, these pollutants in 2021 (the second year of the Covid-19 pandemic) were higher than those in 2020 by 5%, which could be due to high vehicle traffic and the lack of serious policy and law-making by the government to ban urban and interurban traffic. Furthermore, the increase of the NO2 and CO in 2021 was followed by an increase in the deaths caused by Covid-19 and triggering the fourth peak in the Covid-19 cases, signifying a link between exposure to air pollution and Covid-19 mortality in Iran.
Cordycepin, an adenosine analog Induces Apoptosis, ROS Generation, and Suppresses Mitochondrial potentials. Exhibits activities against Dalton’s Lymphoma.
Authors: Shukla Alok , Kumar Sandeep , Kumar Naveen , Patel Anand Kumar , kumar Lokesh , Acharya Arbind 
Published: August 2021

Abstract
Cordycepin exhibits anticancer potentials against various types of cancer cells. However, the multitudes of associated aspects of its anticancer properties against T- cell Lymphoma remains obscure. Based on in vitro studies, we reported that cordycepin exhibits an antineoplastic effect, against Dalton’s Lymphoma (DL) cells. This study illustrates antineoplastic effects and associated mechanisms of cordycepin against tumor cells withdrawn from murine T-cells Lymphoma, designated as Dalton’s Lymphoma. Our study reveals that cordycepin demonstrates tumoricidal activities against tumor cells via activating apoptosis and necrosis, including the surplus level of Reactive oxygen species production, declined mitochondrial membrane potentials, altered cell survival, and chromatin fragmentation. Moreover, this study also reported cordycepin-induced cell cycle arrest in tumor cells which further leads to apoptosis of tumor cells. This investigation elucidates the implication of antitumor actions of cordycepin against T- Cell Lymphoma accompanied by mitochondrial-dependent apoptotic pathway and therefore, have great medicinal significance.
Reflecting the theatralization of life in the prospects of transhumanism
Authors: Prokopovych Lada 
Published: August 2021

The crisis state of society at the beginning of the 21st century is increasingly described as chaos. At the same time, the desire of people to theatricalization of many types of their activities remains unchanged. This gives grounds to consider the theatricality of being as a sociocultural constant, immanently inherent in humanity. The fact that it persists even during periods of cardinal changes, social transformations, civilizational shifts, breaking cultural stereotypes, destruction of traditional institutions and discreditation of established ideals can be explained by the fact that theatricalization of life allows people to cope with sociopsychological discomfort and existential fears, caused by the feeling of total chaos. At the same time, people are faced with the problem of increasingly complex self-identification, which is largely facilitated by the ideas of transhumanism, which actively shatter the already weak notions of what a human being is. One of the approaches to solving this scientific problem is proposed to consider human activity in the context of theatricality of being.
The purpose of the article is to comprehend the practice of theatricalization of various types of human activity in the context of the ideas of transhumanism. The methodological strategy of this research is based on the concept of theatricality of socio-communicative manifestations of culture. Analysis of the theoretical material showed that in the conditions of transhumanism, the development of criteria that make it possible to determine whether a human is still a human or has already turned into something else becomes an urgent task. One of these markers is proposed to consider the desire of a human to theatricalization of various types of their activities. Being one of the sociocultural constants immanently inherent in humanity, theatricality will be present in people's lives as long as they remain human, as long as they feel the need to articulate their social communication.
The development of program of experimental research on the formation of intercultural competence of higher military educational institutions cadets during foreign language training
Authors: Nechyporuk Nataliia 
Published: August 2021

In accordance with the European and world tendencies of professional training of military personnel, it is mandatory to emphasize the problem of forming the intercultural competence among cadets of higher military educational institutions. The process of formation of such a competence should be experimentally approved.
The general approaches to the structure of the experimental research program are analyzed and the necessity of a systematic approach to the formulation of the principles of scientific research, which are a means of proving the research hypothesis, is substantiated.
The program of the pedagogical experiment, aimed at testing the hypothesis, is described, which assumes that the level of intercultural competence of cadets of higher military educational institutions increases under the condition of involvement in the process of active communication by means of intercultural dialogue in the process of learning foreign languages, which reproduces the substantive and social content of professional competences in the process of mastering cultural knowledge and communication skills during reproductive, cognitive-exploratory, research and creative activities.
Tasks, stages, methods of experimental research are characterized. The stages and directions of introduction of the author's model of formation of intercultural competence of higher military educational institutions cadets in the process of foreign language training in accordance with structural components (motivational-value, cognitive-linguistic, communicative-strategic and evaluative-reflexive) are revealed.
The reasons of unsatisfactory results of extracorporeal shock wave lithotripsy in patients with ureterolithiasis
Authors: Vozianov Oleksandr 
Published: August 2021

The article dedicate to the problem of failure of extracorporeal shockwave lithotripsy in patients with ureterolithiasis and reveal the changes which appear in the ureter in the location of the stone.The aim. Analysis of the results of treatment in patients, suffering ureteric stones, using the ureterolithotripsy procedure after failure extracorporeal shockwave lithotripsy.
Materials and methods. In 137 patients with ureteric stones, whom ureterolithotripsy procedure after failure extracorporeal shockwave lithotripsy was conducted, the symptoms of the disease, the diagnostic methods value, efficacy of surgical treatment and reasons of the failure of previous method of treatment were analyzed.
Results. In 135 patients endoscopic removal of stones has been succeeded, in 2 patients because of total obliteration of the ureter, uretero-ureteral anastomosis has been performed. If the symptoms, with are characteristic of ureterolithiasis, persists up to one week stones don’t cause significant macroscopic changes to the ureter wall. If the stone persists in the ureter longer than a week we identified local appearing of oedema. Long–term (more than two months) ureteric stone persistence increase the risk of intramucosal “ingrowth” of the calculi greatly.
Conclusion. The URS and ESWL are high effective and minimal invasive methods of surgical intervention for patients with ureterolithiasis, guaranteeing high level of postoperative “stone free rate”. Prolongation of the stone insertion time in the ureter causes the ureteric wall changes, complicating performance of minimal invasive interventions (ureterolithotripsy and extracorporeal shock–wave lithotripsy) and reduce its efficacy.
Synchronous multiple primary malignant neoplasms: a case report of malignant peritoneal mesothelioma and neuroendocrine rectal tumor
Authors: Bondar Oleksandr , Chetverikov Sergiі , Maksymovskyi Viacheslav , Atanasov Dmytro , Chetverikov Mykhailo , Chetverikova-Ovchynnyk Valeriia 
Published: August 2021

We report a rare case of synchronous malignant peritoneal mesothelioma of the biphasic histological type and neuroendocrine tumor (NET) of the rectum without history of asbestos exposure.
During 2 years since manifestation of the disease the patient underwent 3 cytoreductive surgeries (CRS): removal of the tumor of the sigmoid mesentery, resection of the rectosigmoid junction completeness of cytoreduction (CC) 0 (2017), omentectomy and partial parietal peritonectomy CC-0 (2017), atypical resection of S2, S4, S5 liver, the removal of the abdominal tumor with left-sided en-block hemicolectomy, partial parietal peritonectomy, argon-plasma coagulation of tumor foci on the mesentery of the small intestine CC-2 (2018) and Transanal Minimally Invasive Surgery-removal of neuroendocrine rectal tumor (2017). The patient underwent hyperthermic intraperitoneal chemotherapy (HIPEC) twice (during 2nd and 3rd CRS). Different regimens of HIPEC were performed: cisplatin + doxorubicin (2017) and metamycin C (2018). The patient received 4 courses of adjuvant chemotherapy with cisplatin plus pemetrexed in 2017 and 3 courses of the chemotherapy with gemcitabine and carboplatin plus bevacizumab in 2018.
The patient survived 21 months after the detection of malignant peritoneal mesothelioma in 2017 and died 4 months after the last cytoreductive surgery from the progression of the disease.
Histological subtype of MPMP remains important factor in the prognosis of the disease even on the early stages though patient had received the most aggressive variant of special treatment. Minimally invasive treatment tactics of NET demonstrated clinical effectiveness.
Study of biological and ecological features of permanent ectoparasites of cattle
Authors: Proskurina Iryna , Nahorna Liudmyla 
Published: August 2021

The aim of the research was to study the epizootological features of bovicolosis and sifunculatosis and to determine their biological features.
Materials and methods. Eight groups of animals were examined, 15 animals in each, including cows, heifers and calves. Groups of calves consisted of 13 heifers and 17 bulls. A total of 103 females and 17 male cattle were examined.
Results. During observations, it was noted that in most cases, certain species of ectoparasites were found on different animals. In the case of their simultaneous parasitism on one animal, populations occupied different parts of the host's body. The causative agents of sifunculatosis (L. vituli) and bovicolosis (B. bovis) were determined.
During the study of epizootological features of sifunculatosis and bovicolosis, attention was paid to the seasonality of the invasion – the minimum intensity of the invasion was observed in the warm season, the maximum – in winter. The extent of invasion among calves reached 100 %.
The biological features of ectoparasites were studied. According to the data obtained, it was determined that linognathus are greater than B. bovis at all stages of development. Egg size 0.8–0.9 mm, larvae go through all stages of molting from 0.7 mm to 3.3 mm, adults reach a size of 3.3–4.0 mm. However, the eggs of B. bovis reached 0.3–0.5 mm, the size of the larvae 0.4–1.0 mm, adults ranged from 1 mm to 1.8 mm.
Conclusions. It was noted that the intensity of the infestation of bovicolosis and sifunculatosis increases in the cold season. The young are most prone to lesions.
Comparative assessment of spray nozzles efficacy in the control of fusarium head blight in the barley crops using developed quantitative PCR assay
Authors: Hrytsev Oleh , Liudvinovskyi Oleg , Shevchenko Julia , Dzhagan Veronika , Skivka  Larysa 
Published: August 2021

Fusarium species infect cereal spikes during anthesis and cause Fusarium head blight (FHB), a destructive disease of cereal crops with worldwide economic relevance. The necessity for these phytopathogenic fungi effective control becomes increasingly important for the production of both cultivated plants and those plants seeds. Fungicide application is a key methodology for controlling the disease development and mycotoxin contamination in cereals. Polymerase chain reaction (PCR) is currently the most commonly admitted DNA-based technology for specific, rapid and precise Fusarium detection. We have developed and patented the method for detection and quantitative determination of phytopathogenic fungi F. avenaceum and F. graminearum in plant seeds using Real-Time PCR with a pair of primers, designed to amplify sequences of the internal transcribed spacer at the ribosomal RNA gene cluster of those phytopathogenic fungi. This study was aimed to perform a comparative assessment of the efficacy of different spray nozzles for antifungal treatment to control F. avenaceum and F. graminearum infection of barley grains using a developed qPCR diagnostic system. A single application of a fungicide (active ingredient's content: 250 g/l propiconazole, 80 g/l cyproconazole) at BBCH 65 (middle of flowering) was carried out. For this purpose, four spray nozzles with different technical characteristics were used: Flat Fan 030, Amistar 030, Defy 3D 030 and Vegetable 060 (Pentair, USA). DNA-based fungi detection and identification was performed using conventional PCR and developed qPCR. The level of mycotoxins in barley grain was determined using enzyme-linked immunosorbent assay (ELISA). Grain count in the ear of barley and thousand seed weight (TSW) were also examined.
A single application of the fungicide inhibited the development of FHB and is accompanied by the slight increase of TSW values in treated plants. It was found, that the most effective fungicide was against F. avenaceum and F. graminearum. The inhibitory effect depended on sprayer type. According to qPCR results, the best performance was achieved when using Amistar 030 and Flat Fan (FF) 030 sprayers. The average concentration of deoxynivalenol (DON) content in all barley grain samples were up to 4 times higher than the permissible level. Overall, because of the high contamination levels, found in tested samples, it is possible to state that a single application of the fungicide at the flowering phase was not able to effectively reduce DON contamination in barley samples.
The developed test-system for qPCR provides new important information in the study of the effectiveness of fungicides and development of strategies to control FHB in cereals, not achievable with conventional PCR.
Analysis of the use of industrial crossbreeding to improve the profitability of the pig industry
Authors: Bashchenko Mikhail , Boyko Alexander , Vaschenko Alexander 
Published: August 2021

The aim of the research was to conduct an economic assessment of the use of industrial crossbreeding in the pig industry.
The study was carried out in LLC "Mayak-Agro" (Ukraine) and in the laboratories of the Cherkasy National University named after Bohdan Khmelnitsky and the Cherkasy Experimental Station of Bioresources of the National Academy of Sciences of Ukraine. Ukrainian breeds of pigs were used: (Ukrainian BigWhite-1 (UBW-1), Red White-Belt (RWB) and Duroc of the Ukrainian selection "Steppe" (DUSS)). Breeds of English origin: (Big White (EBW), Landrace (L), Pietrain (P)). Crossbreeds, obtained by crossing the breeds, mentioned above. A comprehensive assessment of the reproductive capacity of a sow was carried out taking into account multiple births, the number of piglets at one month of age and the average daily gain during this period. Growth and development were monitored in terms of changes in live weight by individual weighing at birth and every month to a live weight of 100 and 120 kg.
Regardless of maternal form, in the groups where boars of the breeds Red White-Belt and Pietrain were used, higher indicators of comprehensive assessment of reproductive capacity were obtained. The best fattening qualities characterized piglets, obtained from a combination of sows (1/2UBW-1+1/2L) with boars of the Pietrain breed (P). In comparison with other variants of crosses, in this group the animals reached a live weight of 100 kg 7.6 days earlier. Their feed costs per 1 kg of live weight gain were 3.33 feed units, which corresponds to the expected figure of 3.34 feed units when fattening up to 100 kg in 170 days. In terms of industrial pork production, breeding of animals of the group (1/4UBW-1+1/4L+1/2P) was more profitable, in which the highest level of profitability was obtained - 22.3 % for fattening up to 100 kg and 12.5 % for fattening up to 120 kg. Cultivation of three-breed hybrids to a live weight of over 100 kg led to a decrease in profitability among all research groups. The use of the genotype 1/4UBW-1+1/4L+1/2P in industrial production makes it possible to obtain animals of various weight conditions without significant additional costs and profitability level reduction.
In the course of the research, it was found, that the best option for three-breed crossing is the use of boars of the Pietrain and Red White-Belt breeds. The use of boars of these breeds is ideal for producers looking for bacon pork. The use of boars of the Duroc breed of the Ukrainian selection "Steppe" (DUSS) makes it possible to obtain fatty pork with the possibility of fattening to different weight categories.
Bio protectors’ effect on the composition of some amino acids under alcohol-induced oxidative stress
Authors: Kalachniuk Liliia , Fedyshyn Petro , Smirnov Oleh , Prys-Kadenko Viktoriia , Palonko Roman , Arnauta Oleksii 
Published: August 2021

The studies, which may reveal some elements of regulation between the metabolic processes of proteins (at the level of translation and changes in the amino acid spectrum) as well as catabolism and anabolism of carbohydrates under conditions of pathological deviations of the functioning of the animal organism, are promising, and the search for protective substances of a different nature is necessary.
The aim is to study and analyze a bio protectors’ effect on the composition of some amino acids under alcohol-induced oxidative stress.
During the experimental period, changes in the body weight of rats confirm the depressant effect of alcohol on the dynamics of weight gain of animals during their growth and development, and the positive protective effect of betaine and additives (protein+minerals).
The increased activity of alanine aminotransferase, aspartate aminotransferase, γ-glutamyltransferase in the blood serum of rats in experimental groups of animals with the absence of protectors’ substances in the diet indicates a deviation in the functional capacity of the liver. The determined indices of the content of creatinine and urea were increased significantly that points out on possible pathological deviation of the kidney. Under alcohol substances, changes of such biochemical indexes value as lactate dehydrogenase, superoxide dismutase, and catalase, and the content of malonic dialdehyde indicate oxidative stress. In the case of bio protectors’ presence, values of biochemical parameters become to ones in the animals of control groups.
It was observed, that betaine has a higher potential for the correction of the above pathological abnormalities than protein-containing additives with minerals in the form of chelate, but the last is perspective for further study and their use as a raw material for the development of more complex bio protectors
Parameter optimization and performance analysis of nanofiltration membrane in treatment of compound-contaminated high-hardness water
Authors: Li Guifang , Gao Yuting , Song Wuchang , Xu Fei , Wang Yonglei , Sun Shaohua , Jia Ruibao 
Published: August 2021

Abstract
Increased pollution caused by socio-economic development has led to compound-contaminated high-hardness water pollution. In this study, laboratory-scale nanofiltration (NF) treatment of such water was investigated. Response-surface methodology was used to optimize the NF operating parameters, and a regression model with desalination rate and transmembrane pressure changes as response values was established. The NF membrane efficiencies in contaminant removal from groundwater and surface water with compound-contaminated high hardness and the membrane-fouling characteristics during long-term operation were investigated. The results show that the optimal operating parameters for the NF membrane in the removal of inorganic salts from groundwater are as follows: influent pH 8, influent pressure 1 MPa, and water yield 27.976%. The removal rates for groundwater total hardness, total alkalinity, total soluble solids, K+, Na+, Ca2+, Mg2+, , Cl−, , and were 99.4, 90.3, 84.7, 63.2, 56.8, 99.6, 95.2, 99.6, 68.3, 86.1, and 65.9%, respectively. Surface water contains more complex components; therefore, membrane fouling during surface water is more serious. The NF membrane was operated continuously for more than 35 days under the optimal operating conditions with no serious membrane fouling.
Analysis of different condensing surfaces for dew harvesting
Authors: Corraide da Silva Larissa , Oliveira Filho Delly , Acioli Imbuzeiro Hewlley Maria , Barros Monteiro Paulo Marcos 
Published: August 2021

Abstract
Due to water shortages in several places in the world, alternative water sources such as atmospheric water and greywater have been studied. Dew water harvesting by passive radiative cooling is an unconventional water source that is easy to use, install, and shows great potential in several places in the world. This paper aims to experimentally evaluate the dew yield through passive radiative cooling in Vicosa city, Minas Gerais, Brazil by using standard white plastic for dew harvesting, developed by the International Organization for Dew Utilization (OPUR), polypropylene plastic, black plastic, packaging tape, and anodized aluminum as condensing surfaces during two different periods. The polypropylene plastic and packing tape materials used in this present research have not been researched before in the literature. However, they have demonstrated potential for harvesting dew. As a result, the average water collected was, respectively, 0.151, 0.135, 0.140, 0.127, and 0.046 mm/night using the OPUR standard plastic, polypropylene plastic, black plastic, and packaging tape, and anodized aluminum as condensing surfaces. Although relatively small water volumes were harvested, this water should not be neglected since it can supplement the water demand for irrigation, human and animal consumption, among other uses in drought periods.