bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cardiovascular Disease Risk Factors and 10 Year Risk of Cardiovascular Events among Women over the Age of 40 Years in an Urban Underprivileged Area of Bangalore City
Authors: Johnson Avita Rose , Arasu Sakthi , Gnanaselvam Nancy Angeline 
Published: November 2021

Background:
Cardiovascular disease (CVD) is one of the leading causes of death among Indian women but not a focus of current strategies to improve women's health.

Objectives:
To assess 10-year CVD risk and estimate the prevalence of CVD risk factors among underprivileged women.

Methods:
A cross-sectional study among women aged 40–79 years in an urban underprivileged area of Bangalore city, using nonlaboratory-based World Health Organization and the International Society of Hypertension risk prediction chart and INTERHEART list of CVD risk factors. Blood pressure, random blood sugar, height, weight, and waist circumference were measured. The Chi-square test was done for the association between CVD risk status and risk factors. Multiple logistic regression performed to calculate adjusted odds ratios (ORs).

Results:
Of 1027 women, 11% women had high risk of CVD (≥20% risk of fatal/nonfatal cardiovascular event within next 10 years). The prevalence of CVD risk factors was high with 20.2% diabetes, 53.7% hypertension, 77% overweight/obesity, and 92% central obesity. Majority were physically inactive with unhealthy diet, lacking daily fruits and vegetables, excess consumption of salty food, junk food, red meat, and excess oil. Significantly higher CVD risk found among women who were sedentary during leisure time (P = 0.028), single/separated/widowed women (OR = 1.84 [1.26–4.29] P = 0.002), and women who did not walk or cycle as a regular means of transport (OR = 1.47 [1.98–2.19] P = 0.041).

Conclusion:
High risk of CVD among underprivileged women reveals an urgent need for community-based interventions for prevention of CVD. Screening and management of diabetes and hypertension must include weight reduction and health education strategies. Policy-makers need to initiate efforts toward improving affordability of healthy diets for the urban underprivileged.
Correlation of inhA mutations and ethionamide susceptibility: Experience from national reference center for tuberculosis
Authors: Sarin Rohit , Bhalla Manpreet , Kumar Gavish , Singh Anjali , Myneedu Vithal Prasad , Singhal Ritu 
Published: October 2021

Background:
Detection of ethionamide (ETH) resistance is crucial as it is part of antitubercular regime. It is crucial to examine the role of inhA gene mutations as a surrogate marker for the detection of ETH resistance, in the Indian context. The present retrospective study was designed with this objective.

Subjects and Methods:
The study was conducted in National Reference Laboratory within the tertiary care institute from January 1, 2018, to June 30, 2019, over 18 months duration. A total of 6612 sputum samples from presumptive multidrug-resistant tuberculosis (TB) patients were received from four districts of Delhi, outdoor and inpatients. Line probe assay (LPA) was performed for smear-positive or culture-positive samples for Mycobacterium tuberculosis. All isolates found to be INH resistant by LPA were cultured and phenotypic susceptibility to ETH was conducted for selected isolates as per the guidelines.

Results:
A total of 246 isolates were analyzed, for which phenotypic susceptibility to ETH and mutations in inhA were available. ETH resistance was detected among 87/108 (80.5%) isolates with inhA mutation. Sensitivity and specificity of inhA mutation for detection of ETH resistance were 80.5% and 83.8%, respectively. No inhA mutation was detected in 29/116 (25%) ETH-resistant isolates in our study, whereas ETH was found to be phenotypically susceptible in spite of the presence of inhA mutation among 21/130 (16.1%) isolates.

Conclusions:
Mutations in inhA gene in LPA predict ETH resistance with fairly good sensitivity and specificity. However, it is imperative to perform phenotypic detection of ETH resistance at proper concentration, in addition to detecting inhA mutation.
Determining pulmonary function and the associated risk factors among stone quarry workers in a suburban area of Chennai, Tamil Nadu, India
Authors: Arumugam Elangovan , Rajkumar Prabu , Dhanaraj Baskaran , Govindasamy Elavarasu , Jaganathasamy Nagaraj , Mathiyazhakan Malathi , Mariappan V E Nethaji , Shanmugam Sivakumar , Durairajan Chokkalingam , Rajadurai Sivanesan , Joshua Vasna , Jayaraman Yuvaraj 
Published: October 2021

Background:
Stone quarrying activities generate dust and fine particulate matters of silica and heavy metals. The prolonged exposure to suspended particulates leads to fatal respiratory complications. Occupational pulmonary complications are poorly characterized among quarry workers in Tamil Nadu.

Objectives:
This study aims to assess pulmonary function and determine the associated risk factors among quarry workers.

Materials and Methods:
A comparative, cross-sectional study was conducted from April 2014 to January 2015 among workers at seven stone quarries in Chennai and residents within a 5 Km radius. Pulmonary function tests (PFT) and sputum analysis were done.

Results:
Overall, 670 participants were enrolled in the study, with a median age of 37 years. Comparatively, the mean PFT measures were significantly lower in quarry workers with a higher proportion of airflow obstruction and tuberculosis infection.

Conclusion:
The risk of airflow obstruction among quarry workers increased with smoking and longer duration of work years in quarry.
Functional impairment in bronchiectasis: Spirometry parameters versus St. George’s Respiratory Questionnaire scores: Any co-relation?
Authors: Singh Priyanka , Katoch C. D. S. , Vardhan Vasu , Chopra Manu , Singh Sarvinder , Ahuja Nitin 
Published: October 2021

Objectives:
Bronchiectasis is a common respiratory disease which has significant morbidity and mortality. Health-related quality of life scores are not routinely used for the assessment of bronchiectasis. The present study was undertaken with an aim to assess the clinical profile and functional impairment using spirometry in patients with bronchiectasis and to co-relate functional impairment with their St. George’s Respiratory Questionnaire (SGRQ) score.

Methodology:
This was a cross-sectional study carried out on 102 patients of bronchiectasis. All patients were assessed for clinical profile, spirometry, and SGRQ scores. Forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC were measured and compared with SGRQ scores. Data analysis was done using SPSS version 20.0 and MS-Excel.

Results:
Obstruction was found in 62.7% and significant bronchodilator reversibility was observed in 30.4%. All spirometry parameters individually and combined showed a negative co-relation which was stastically significant (P < 0.001). Best co-relation was with FEV1 r = −0.809; symptom score, r = −0.821; activity score, r= −0.849; impact score and r = −0.873 total score. FVC% versus symptoms score r = −0.735; activity score r = −0.729, impacts score r = −0.778; total score r = −0.792. FEV1/FVC versus symptoms score r = −0.227, activity score r = −0.278, impacts score r = −0.263, total score r = −0.274.

Conclusion:
SGRQ scores have shown good correlation with functional impairment. It can be used as a modality to evaluate health status of patient in resource constraint settings.
A Multicenter Study on the Safety and Efficacy of Bronchial Thermoplasty in Adults with Severe Asthma
Authors: Madan Karan , Suri Tejas M , Mittal Saurabh , Maturu Venkata Nagarjuna , Pattabhiraman VR , Mohan Anant , Srinivasan Arjun , Sivaramkrishnan Mahadevan , Prasad KT , Agarwal Ritesh , Tiwari Pawan , Hadda Vijay , Mehta Ravindra , Guleria Randeep 
Published: October 2021

Background and Aim:
Bronchial thermoplasty (BT) is a treatment option for patients with severe asthma. BT involves controlled delivery of radiofrequency energy using a bronchoscopic catheter, thereby reducing bronchial hyperreactivity. Herein, we describe our experience on the safety and efficacy of BT in severe asthma.

Methods:
This was a retrospective multicenter study of subjects who underwent BT at four centers across India.

Results:
We included 36 subjects (mean ± standard deviation [SD] age, 50.9 ± 11.5 years, women [69.44%]) undergoing 105 BT treatment sessions. All the subjects met the American Thoracic Society/European Respiratory Society criteria for severe asthma, 22.2% were requiring oral maintenance glucocorticoids. The mean ± SD baseline %predicted forced expiratory volume in one second (FEV1) was 62.07 ± 18.54. The median interquartile range (IQR) annual asthma exacerbation rate in the year preceding BT was 3.5 (1–10). We encountered intraprocedural complications in 7 (6.7%) sessions. An exacerbation of asthma following BT occurred in 6 (5.7%) procedures. We observed a significant improvement in the asthma control test and the asthma control questionnaire scores following BT. The quality of life (asthma quality of life questionnaire) also significantly improved. We noted a significant reduction in the number of exacerbations following BT (median [IQR], 3 [1–10] per year pre-BT versus 0.5 [0–3] per year post-BT, P < 0.001). No significant change occurred in the %predicted FEV1 following BT.

Conclusion:
BT is a feasible treatment option in patients with severe asthma. More extensive studies are required to establish the efficacy of BT in real-life settings.
Prevalence and predictors of pulmonary embolism in patients with acute exacerbation of chronic obstructive pulmonary disease
Authors: Chaudhary Nasir , Khan Umar Hafiz , Shah Tajamul Hussain , Shaheen Feroze , Mantoo Suhail , Qadri Syed Mudasir , Mehfooz Nazia , Shabir Afshan , Siraj Farhana , Shah Sonaullah , Koul Parvaiz A , Jan Rafi Ahmed 
Published: October 2021

Background:
The prevalence of pulmonary embolism (PE) in patients of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) varies over a wide range. Early detection and treatment of PE in AECOPD is a key to improve patient outcome. The purpose of the study was to investigate the prevalence and predictors of PE in patients of AECOPD in a high burden region of North India.

Materials and Methods:
This prospective study included patients of AECOPD with no obvious cause of exacerbation on initial evaluation. Apart from routine workup, the participants underwent assessment of D-dimer, compression ultrasound and venous Doppler ultrasound of the lower limbs and pelvic veins, and a multidetector computed tomography pulmonary angiography.

Results:
A total of 100 patients of AECOPD with unknown etiology were included. PE as a possible cause of AE-COPD was observed in 14% of patients. Among the participants with PE, 63% (n = 9) had a concomitant presence of lower extremity deep venous thrombosis. Hemoptysis and chest pain were significantly higher in patients of AECOPD with PE ([35.7% vs. 7%, P = 0.002] and [92.9% vs. 38.4%, P = 0.001]). Likelihood of PE was significantly higher in patients who presented with tachycardia, tachypnea, respiratory alkalosis (PaCO2 <45 mmHg and pH >7.45), and hypotension. No difference was observed between the two groups in terms of in-hospital mortality, age, sex distribution, and risk factors for embolism except for the previous history of venous thromboembolism (35.7% vs. 12.8% P = 0.03).

Conclusion:
PE was probably responsible for AECOPD in 14% of patients with no obvious cause on initial assessment. Patients who present with chest pain, hemoptysis, tachypnea, tachycardia, and respiratory alkalosis should be particularly screened for PE.
The ultrafilter number and
Authors: Guzmán Osvaldo 
Published: November 2021

AbstractThe cardinal invariant
$\mathfrak {hm}$
is defined as the minimum size of a family of
$\mathsf {c}_{\mathsf {min}}$
-monochromatic sets that cover
$2^{\omega }$
(where
$\mathsf {c}_{\mathsf {min}}( x,y) $
is the parity of the biggest initial segment both x and y have in common). We prove that
$\mathfrak {hm}=\omega _{1}$
holds in Shelah’s model of
$\mathfrak {i<u},$
so the inequality
$\mathfrak {hm<u}$
is consistent with the axioms of
$\mathsf {ZFC}$
. This answers a question of Thilo Weinert. We prove that the diamond principle
$\mathfrak {\Diamond }_{\mathfrak {d}}$
also holds in that model.
SÍFILIS NA GESTAÇÃO - BARREIRAS NA ASSISTÊNCIA PRÉ-NATAL PARA A PREVENÇÃO DA TRANSMISSÃO VERTICAL
Authors: Nery Sabrina Beatriz Mendes , Souza Mariana Silva , Araujo Suellen Munique , Alves Erik Bernardes Moreira , Souza Cícero Santos , Eufrazino Junior José , Andrade Flávia  Samara Freitas de , Sousa Emanuel Osvaldo de , Moreno Lucas dos Santos , Carvalho Maria da Conceição de Oliveira , Cardoso Francisca Kelly Macedo , Silva Renata Pedro 
Published: October 2021

Com o intuito de responder à problemática desta pesquisa, objetivou-se identificar as barreiras na assistência pré-natal para a prevenção da transmissão vertical da sífilis na gestação. Esse estudo trata-se de uma revisão integrativa da literatura, de natureza descritiva e de abordagem qualitativa, com as pesquisas realizadas nos bancos de dados da MEDLINE, LILACS e BDENF, em que foram incluídos trabalhos completos, nos idiomas português e inglês, disponíveis eletronicamente e de forma gratuita, publicados no período de 2016 a 2021 e que abordavam a temática proposta. Excluiu-se trabalhos que não abordavam o assunto de interesse ou não respondessem à questão norteadora, além de publicações duplicadas em mais de uma base de dados. O estudo foi composto pela análise de 9 publicações. Os achados mostraram que as barreiras na assistência pré-natal para a prevenção da SC foram abordadas de forma diversificada pela literatura. Com isso, é de grande relevância destacar que apesar da gestante realizar o pré-natal corretamente, ainda existe muitas falhas durante essa assistência, o que gera impactos negativos tanto para a gestante quanto para o neonato. Conclui-se que o manejo da sífilis gestacional tem sido realizado de forma incorreta, por meio do diagnóstico tardio e, consequentemente, a não realização do tratamento no período adequado, como também a não adesão ao esquema terapêutico tanto pela gestante quanto pelo seu parceiro
Pengaruh Pelatihan terhadap Kompetensi Guru dalam Meningkatkan Aktivitas Motorik Halus (Feeding)
Authors: Aktifah Nurul , Fajriyah Nuniek Nizmah , Faradisi Firman 
Published: November 2021

Cerebral Palsy (CP) merupakan kerusakan pada otak yang bersifat non-progresif dan terjadi pada proses tumbuh kembang anak. Hambatan yang muncul pada anak CP salah satunya adalah hambatan motoric halus. Penanganan CP membutuhkan peran serta berbagai disiplin ilmu, salah satunya adalah guru, namun banyak guru yang belum mengetahui latihan dasar untuk meningkatkan kemampuan motoric halus. Latihan Mandiri pada Guru SLB Melalui Pemberian Intervensi Bermain merupakan upaya untuk meningkatkan kompetensi guru dalam meningkatkan aktivitas motoric halus pada anak CP. Tujuan penelitian ini adalah untuk mengetahui pengaruh pelatihan terhadap peningkatan kompetensi guru. Desain penelitian menggunakan quasi experiment design tipe one group pre post without control group design. Analisa data menggunakan uji Paired T test. Hasil uji didapatkan p value 0,001 <α 0,05, hal ini menunjukkan terdapat pengaruh pemberian pelatihan terhadap pengetahuan responden. Peningkatan kompetensi guru ini diharapkan akan berdampak pada peningkatan motoric halus anak CP.

Kata kunci: pelatihan, intervensi bermain, motoric halus
REFİK HALİD KARAY’IN ROMANLARINDA BAKIŞ AÇISI VE ANLATICI DÜZLEMİ
Authors: TOPDAŞ ÇELİK Fatma 
Published: October 2021

Anlatmaya bağlı edebî metinlerdeki kişiler dünyası, mekân ve zaman algısı, dil ve üslup anlatıcının algısı ve bilgisi doğrultusunda oluşur. Bu açıdan anlatmaya bağlı edebî metinlerde bakış açısı ve anlatıcı metni kuran ve şekillendiren yapısal unsurlardandır. Yazarın yapacağı tercihe göre hâkim/tanrısal bakış açısı, kahraman bakış açısı ve tanık/gözlemci bakış açısı doğrultusunda kimlik kazanan anlatıcının eserdeki konumunu da bu bakış açısı belirler. Anlatıcının sınırlı ya da sınırsız bilgi ve algı niteliğine sahip olması benimsenen bakış açısının sonucudur. Söylem düzleminde anlatım evrenini kuran bakış açısı ve anlatıcı unsuru, anlatım teknik ve yöntemlerini de belirleyerek yazarın üslubunun ayrışmasını ve görünür kılınmasını sağlar; aynı zamanda romanlardaki ülkü ve karşıdeğerlerin aktarımında yansıttığı görüş ve benimsediği tutum sebebiyle de çok işlevli bir yapısal unsura dönüşür.
Bu çalışmada Türk edebiyatında hikâye ve mizah yazıları kadar romanlarıyla da yer edinen Refik Halid’in roman türündeki yirmi eserinde, bakış açısı ve anlatıcı unsuru metindeki işlevi ve nitelikleri bakımından incelendi. Bu inceleme sonucunda, kurgularını genel olarak geleneksel/klasik roman yapısı üzerine temellendiren Refik Halid Karay’ın romanlarından on dört tanesinin hâkim bakış açısı ve anlatıcı, dört tanesinin kahraman bakış açısı ve anlatıcı, iki tanesinin ise karma/çoklu bakış açısı ve anlatıcı düzlemine sahip olduğu tespit edildi.
Pengaruh Produk dan Iklan Terhadap Keputusan Pembelian Yamaha Jupiter MX
Authors: Mardjiono River Diego 
Published: October 2021

The purpose of this study was to determine the simultaneous and partial influence of products and advertisements and the most dominant variables on the purchase decision of Yamaha Jupiter MX motorcycles. The type of research used is explanatory research. The population is JMC Community (Jupiter MX Club) Surabaya as many as 56 people who know the Jupiter MX ad version of 'Bridge Collapse'. Saturated sampling technique is the entire population. The analysis technique used is multiple regressions with significant tests of F and t. The results of the analysis showed that products and advertisements simultaneously had a significant effect on purchasing decisions. While the results of the analysis partially, it was concluded that: (1) The product has a significant effect on purchasing decisions. (2) Advertising has a significant effect on purchasing decisions. Product variables have a dominant effect on purchasing decisions. Based on the findings of this study, Yamaha manufacturers should still pay attention to product variables and advertising because it is proven to have a large influence on consumer purchasing decisions. As per the lowest score, then the quality of Jupiter MX products needs to be improved.
Keyword: Product, Advertisement, Buying Decision.
Analisis Dampak Rasio Profitabilitas dan Rasio Solvabilitas terhadap Harga Saham pada Sub Sektor Jasa Asuransi
Authors: Dhany Umi Rahma , Yusuf Muhammad Rizki , Hendra Joni 
Published: October 2021

This study has several objectives, namely to determine the simultaneous, partial and dominant influence between the variables of return on assets (ROA), return on equity (ROE), and debt to equity ratio (DER) on stock prices in insurance service sub-sector companies that listed on the Indonesia Stock Exchange. This type of research is associative quantitative research and data collection methods using documentation studies and literature studies. The sampling technique used purposive sampling by taking a sample of 5 years with 10 companies. The results showed that the independent variables had a simultaneous effect on profitability. The t-test shows that the ROA variable has a partial effect on Stock Prices and the ROE variable has a partial effect on Stock Prices and also the DER variable has a partial effect on Stock Prices.
EFEKTIVITAS PENGGUNAAN MEDIA VIDEO PEMBELAJARAN DI SMP NEGERI 2 TARAKAN PADA MASA PANDEMI COVID-19
Authors: MACHFUD MOCHAMMAD 
Published: November 2021

One of the important factors in learning activities is the existence of learning media that attracts the attention of students. Media is an intermediary tool between educators and students and is very supportive in the delivery of learning material to make it easier to learn and understand it. The outbreak of the Covid-19 pandemic in Indonesia has an impact on the Indonesian education process. Educational activities must be carried out online, students and teachers do not meet each other. So that the learning media that is an alternative for educators during the Covid-19 pandemic is the use of learning video media. The purpose of this study was to see the effectiveness of using video media in learning at SMP Negeri Tarakan during the Covid-19 pandemic based on the educator's perspective. The methodology used in this study is descriptive quantitative with an instrument in the form of a questionnaire given to teachers at SMP Negeri 2 Tarakan in October 2021. The results show that the implementation of learning during the Covid-19 pandemic using learning video media by subject teachers has goes well. Media in the form of learning videos is effectively used during the Covid-19 pandemic, because it makes it easier for educators to teach material that needs explanation and makes it easier for students to understand learning material.
ABSTRAKSalah satu faktor penting dalam kegiatan pembelajaran adalah adanya media pembelajaran yang menarik perhatian peserta didik. Media merupakan alat perantara antara pendidik dengan peserta didik dan sangat menunjang dalam penyampaian materi pembelajaran agar lebih mudah untuk mempelajari dan memahaminya. Mewabahnya pandemi Covid-19 di Indonesia memberikan pengaruh bagi proses pendidikan Indonesia. Kegiatan pendidikan harus dilaksanakan dengan daring peserta didik dan guru tidak saling bertemu. Sehingga media pembelajaran yang menjadi alternatif pendidik saat pandemi Covid-19 adalah penggunaan media video pembelajaran. Tujuan dari penelitian ini adalah untuk melihat efektivitas penggunaan media video dalam pembelajaran di SMP Negeri Tarakan selama masa pandemi Covid-19 berdasarkan perspektif pendidik. Metodologi yang digunakan pada penelitian ini adalah deskriptif kuantitatif dengan instrumen berupa angket yang diberikan kepada guru-guru di SMP Negeri 2 Tarakan pada bulan Oktober 2021. Hasil penelitian memperlihatkan bahwa pelaksanaan pembelajaran pada masa pandemi Covid-19 dengan menggunakan media video pembelajaran oleh guru mapel telah berjalan dengan baik. Media berupa video pembelajaran efektif digunakan pada masa pandemi Covid-19, karena memudahkan pendidik dalam mengajarkan materi yang perlu adanya penjelasan serta memudahkan peserta didik memahami materi pembelajaran.