bluuebunny/crossref_metadata_2025_split huggingface dataset:
Affect Reactivity to Daily Stressors Mediates the Relationship Between Personality Traits and Physical Health
Authors: Leger Kate , Turiano Nicholas , Bowling William , Burris Jessica , Almeida David 
Published: December 2021

Abstract
Researchers hypothesize that how people react to daily stressful events partly explains the personality-health relationship, yet no study has examined longitudinal associations between these factors. The current study examined the role of negative affect reactivity to daily stressors as a mediating pathway between personality and physical health outcomes using three waves of data spanning 20-years from a nationwide probability sample of 1,176 adults. Results indicate that Wave 1 neuroticism was associated with greater negative affect reactivity at Wave 2, which then predicted the development of chronic conditions and functional limitations at Wave 3. Higher conscientiousness was associated with less negative affect reactivity, which in turn predicted better physical health at Wave 3. Negative affect reactivity partially mediated both personality traits and physical. These findings highlight the usefulness of using a daily stress framework for understanding how personality impacts health over time, which has important implications for disease prevention.
Are All Domains of Life Satisfaction Equal? Differential Associations With Health and Well-Being in Older Adults
Authors: Nakamura Julia , Delaney Scott , Diener Ed , VanderWeele Tyler , Kim Eric 
Published: December 2021

Abstract
Growing evidence documents strong associations between overall life satisfaction and favorable health and well-being outcomes. However, because most previous studies have assessed satisfaction with one’s life as a whole, we know little about whether specific domains of life satisfaction (e.g., satisfaction with income) might be driving better health and well-being outcomes. Data were from 13,752 participants in the Health and Retirement Study—a nationally representative cohort of US adults aged &gt;or=50. We evaluated if positive changes in seven domains of life satisfaction (between t0;2008/2010 and t1;2012/2014) were associated with 35 indicators of physical, behavioral, and psychosocial health and well-being (at t2;2016/2018). Satisfaction with family life and non-work activities showed the largest associations with subsequent psychological factors, followed by satisfaction with financial situation and income. Effect estimates were double in magnitude for certain domains of life satisfaction (e.g., the association between satisfaction with family life and purpose in life (β=0.22, 95% CI:0.16,0.27) was more than twice as large as the association between satisfaction with housing and purpose in life (β=0.09, 95% CI:0.02,0.16). Further, some domains showed associations with physical health outcomes (e.g., participants with the highest satisfaction with health had a 21% decreased mortality risk (95% CI: 0.66,0.95)), health behaviors (e.g., higher satisfaction with income decreased risk of sleep problems by 11% (95% CI:0.80,0.99)), and social factors (e.g., loneliness (β: -0.16 to -0.42)). Individual domains of life satisfaction might be novel targets for interventions and policies seeking to enhance specific facets of health and well-being in our rapidly aging population.
Purpose in Life: A Reconceptualization for Very Late Life
Authors: Anderson Keith , Fields Noelle , Cassidy Jessica , Peters-Beumer Lisa 
Published: December 2021

Abstract
Across disciplines, we have long sought to understand the factors that contribute to purpose in life. Theorists have posited that having life goals, feeling productive, and remaining active are essential contributing elements to purpose in life (Crumbaugh & Maholick, 1969; Rowe & Kahn, 1997; Ryff, 1989). While these factors can undoubtedly contribute to purpose in life, they may not fully explain purpose in life for older adults in very late life (85 years old and older) who have long past and short future time horizons. In this presentation, we explore the concept of purpose in life for older adults in very late life and how current measures may not fully or accurately apply to this group. We examine the two most commonly used measures of purpose in life, the Purpose in Life Test (Crumbaugh & Maholick, 1964, 1969) and the Ryff Purpose Subscale (Ryff, 1989; Ryff & Keyes, 1995), and identify specific items that should be reconsidered for use with older adults in very late life. We then reconceptualize purpose in life for the oldest old based on several foundational theories, including Socioemotional Selectivity Theory, the Theory of Gerotranscendence, and Terror Management Theory. Stemming from this analysis, we posit that purpose in life in very life consists of three domains – the very long past, the very near future, and the transcendental post-mortem. Based upon this reconceptualization, we recommend the development of new measures of purpose of life in very late life that capture these three domains.
Feasibility Study of a Tablet-Based Intervention to Enhance the Meaning in Life Among Older Adults
Authors: Nam Seok In , Han Sangyoon 
Published: December 2021

Abstract
Recommendations to improve older adults' health and well-being focus on enhancing meaning in life through social interaction. Research studies have suggested that a tablet-based intervention can create opportunities to enhance meaning in life, thus reducing social isolation and loneliness. The purpose of this study was to examine the feasibility of using a tablet-based intervention to enhance meaning in life among older adults. Senior Meaning in Life Enhancement (SMiLE) is a tablet-based application developed and implemented based on person-centered counseling, logotherapy, and Acceptance Commitment Therapy (ACT). Thirty-one participants (adults aged over 65 years) were randomized for intervention (n = 15) or waitlist control (n = 16). The intervention group received a tablet with our embedded app. Participants were invited to participate in the app-based 2-month program for 30-minutes each day with the tablet. We evaluated pre-and post-semi-structured interviews, meaning in life scales, and usability tests. Data were analyzed using thematic analyses, descriptive statistics, and Mann–Whitney and Wilcoxon tests. Findings confirmed that at two months after the intervention, there was a statistically significant difference in the gap between pre-and post-meaning in life scores between the two groups (Z = -2.08, p &lt; .05). Furthermore, qualitative findings included positive changes in behavior, relationships, and usability. This pilot study suggests the feasibility of a tablet-based intervention in older adults and demonstrates its potential benefit for meaning in life. These findings are valuable to researchers, practitioners, and designers interested in technological interventions for older adults.
Personal Network Bridging Potential Among Rural and Older Populations
Authors: Roth Adam , Peng Siyun , Perry Brea 
Published: December 2021

Abstract
Personal social networks play a fundamental role in the daily lives of older adults. Although many studies examine how life course factors and personal preferences shape network formation, fewer consider how the places in which older adults live present opportunities and obstacles to cultivate social relationships. In the present study, we explore how geographic context is associated with the ability to interact with non-overlapping social groups within one’s personal network (i.e., network bridging). This unique network formation offers older adults access to diverse social stimuli, non-redundant information, and social autonomy. By analyzing data from the Person-to-Person Health Interview Survey (N=709), we found that a minority of respondents reported the ability to bridge social groups within their networks. Respondents residing in rural and semi-rural counties engaged in fewer non-overlapping social groups compared to those residing in urban counties. These findings suggest that the communities in which older adults live condition opportunities for accessing unique social resources. Identifying the link between geographic residence and personal network structure has important implications for how individuals navigate the uncertainty and elevated support needs of later life. Additional research adopting a social network perspective is needed to provide insight into geographic health disparities occurring among the older population.
Digital Developments in Society That Persons 75 Years and Older Have Been Part of: A Scoping Review
Authors: Raja Moonika , Bjerkan Jorunn , Kymre Ingjerd , Galvin Kathleen , Uhrenfeldt Lisbeth 
Published: December 2021

Abstract
The population in Europe is ageing and people are becoming more than ever dependent on digital technologies. The present study aims to map relevant evidence about digital developments in society involving people aged 75 and over in European countries. It focuses on their experiences and the main barriers to, and facilitators of, societal digital demands. Scoping reviews can be used when the purpose is to identify types of available evidence and clarify concepts, this process was guided by a framework proposed by Arksey and O`Malley. The studies included in the review covered digital technology, digital devices and telehealth, and the context covered participants` own home or surroundings. A comprehensive search was made on CINAHL, Embase, Pubmed/MEDLINE, Scopus and Open Grey. Out of 727 identified citations, 13 sources which met the inclusion criteria (9 original study articles, 2 theses, 1 letter about a product and 1 project report). The studies included varied in their focus, design and location. Older European citizens have experienced technology making life easier and the opposite. The outstanding facilitator found was that technology should be easy to use. Interestingly, both social support and lack of social support were found as facilitators of using new technology and difficulty in remembering the instructions was seen as an important barrier. As technology develops rapidly, there is a need for new and additional research among older European citizens. Future research should cover participants` access to the devices, social support and the technical solutions most relevant to older people today.
Early Life Racial Discrimination, Racial Centrality, and Allostatic Load Among African American Older Adults
Authors: Thomas Tobin Courtney S , Gutiérrez Ángela , Bell Caryn N , Thorpe Roland J 
Published: December 2021

AbstractBackground and ObjectivesPrior research documents accelerated physiological aging among African Americans due to their greater lifetime exposure to social and economic adversity. Yet, less is known about the mechanisms through which early life stressors, such as early life racial discrimination (ELRD), and later life psychosocial resources, such as racial centrality (i.e., importance of Black identity to one’s sense of self), interact to shape allostatic load (AL) in adulthood. We evaluate the life course processes linking ELRD, adult racial centrality, and adult AL among older African Americans.Research Design and MethodsData from the Nashville Stress and Health Study included African Americans aged 50 and older (N = 260). Poisson regression models assessed the links between ELRD, adult centrality, and adult AL. Interactions determined whether ELRD conditions the centrality–AL association in adulthood.ResultsAdolescent ELRD conferred significantly higher levels of adult centrality and 32% increased risk of high adult AL. Greater adult centrality was linked to high adult AL, but the ELRD–adult AL association was not explained by centrality. However, ELRD and centrality interact to shape adult AL, such that racial centrality was protective against high adult AL for those who experienced racial discrimination as children or adolescents.Discussion and ImplicationsFindings highlight the multiple pathways through which racism-related stressors and psychosocial resources interact to shape physiological dysregulation in later life and underscore the health significance of racial identity for older African Americans. Clinicians and public health professionals should assess early life stressors and foster psychosocial resilience to promote healthy aging.
A Topography of Data Commons: From Regulation to Private Dynamism
Authors: Ottolia Andrea , Sappa Cristiana 
Published: December 2021

Abstract
Knowledge is subject to enclosure through digital technology and legal rules. Data collected, stored and pooled by the Internet of Things (IoT) or Artificial Intelligence (AI) are no exception to this. Operators acting in the markets related to the algorithmic society may have a quite diversified range of intellectual property rights (IPRs) to protect the information they produce and manage. This is exploited through algorithmic processing techniques, aggregating collected data for the generation of new ones, thus creating additional information and knowledge. This paper studies whether and when data, information and knowledge, presented within the Big Data, IoT and AI structures, may be considered and exploited as commons. The analysis is not aimed at stating that commons should be the general solution for the algorithmic society. Nor does it endorse legal interpretations unilaterally favoring openness and limiting IPR protection and privacy rules (though this could be the case under certain circumstances). The question is to establish whether a certain level of commons should be provided by regulation or left to spontaneous private initiatives. In this regard, two different meanings of data commons are used in this work. The first one refers to the open access systems provided by regulation, equivalent to a public domain protection, and opposed to exclusivity mechanisms. The second refers to data commons which are privately ‘constructed’ on top of background regulation and manage resources for a limited set of claimants.
A conceptual framework for analysing partnership and synergy in a global health alliance: case of the UK Public Health Rapid Support Team
Authors: Raftery Philomena , Hossain Mazeda , Palmer Jennifer 
Published: December 2021

AbstractPartnerships have become increasingly important in addressing complex global health challenges, a reality exemplified by the COVID-19 pandemic and previous infectious disease epidemics. Partnerships offer opportunities to create synergistic outcomes by capitalizing on complimentary skills, knowledge and resources. Despite the importance of understanding partnership functioning, research on collaboration is sparse and fragmented, with few conceptual frameworks applied to evaluate real-life partnerships in global health. In this study, we aimed to adapt and apply the Bergan Model of Collaborative Functioning (BMCF) to analyse partnership functioning in the UK Public Health Rapid Support Team (UK-PHRST), a government–academic partnership, dedicated to outbreak response and research in low- and middle-income countries. We conducted a literature review identifying important elements to adapt the framework, followed by a qualitative case study to characterize how each element, and the dynamics between them, influenced functioning in the UK-PHRST, exploring emerging themes to further refine the framework. Elements of the BMCF that our study reinforced as important included the partnership’s mission, partner resources (skills, expertise and networks), leadership, the external environment, management systems and communication. Additional elements identified in the literature and critical to partnership functioning of the UK-PHRST included governance and financial structures adopted, trust and power balance, organizational culture, strategy and evaluation and knowledge management. Because of the way the UK-PHRST was structured, fostering team cohesion was an important indicator of synergy, alongside collaborative advantage. Dividing the funding and governance equally between organizations was considered crucial for maintaining institutional balance; however, diverse organizational cultures, weak communication practices and perceived power imbalances compromised team cohesion. Our analysis allowed us to make recommendations to improve partnership functioning at a critical time in the evolution of the UK-PHRST. The analysis approach and framework presented here can be used to evaluate and strengthen the management of global health partnerships to realize synergy.
Five-year retention of volunteer community health workers in rural Uganda: a population-based retrospective cohort
Authors: Hobbs Amy J , Manalili Kimberly , Turyakira Eleanor , Kabakyenga Jerome , Kyomuhangi Teddy , Nettel-Aguirre Alberto , Kyokushaba Clare , Rwandekeye Polar , Brenner Jennifer L 
Published: December 2021

Abstract
Community health workers (CHWs) effectively improve maternal, newborn and child health (MNCH) outcomes in low-to-middle-income countries. However, CHW retention remains a challenge. This retrospective registry analysis evaluated medium-term retention of volunteer CHWs in two rural Ugandan districts, trained during a district-wide MNCH initiative. From 2012 to 2014, the Healthy Child Uganda partnership facilitated district-led CHW programme scale-up. CHW retention was tracked prospectively from the start of the intervention up to 2 years. Additional follow-up occurred at 5 years to confirm retention status. Database analysis assessed CHW demographic characteristics, retention rates and exit reasons 5 years post-intervention. A multivariable logistic regression model examined 5-year retention-associated characteristics. Of the original cohort of 2317 CHWs, 70% were female. The mean age was 38.8 years (standard deviation, SD: 10.0). Sixty months (5 years) after the start of the intervention, 84% of CHWs remained active. Of those exiting (n = 377), 63% reported a ‘logistical’ reason, such as relocation (n = 96), new job (n = 51) or death (n = 30). Sex [male, female; odds ratio (OR) = 1.53; 95% confidence interval (CI): 1 · 20–1 · 96] and age group (&lt;25 years, 30–59; OR = 0.40; 95% CI: 0.25–0.62) were significantly associated with 5-year retention in multivariable modelling. Education completion (secondary school, primary) was not significantly associated with retention in adjusted analyses. CHWs in this relatively large cohort, trained and supervised within a national CHW programme and district-wide MNCH initiative, were retained over the medium term. Importantly, high 5-year retention in this intervention counters findings from other studies suggesting low retention in government-led and volunteer CHW programmes. Encouragingly, findings from our study suggest that retention was high, not significantly associated with timing of external partner support and largely not attributed to the CHW role i.e. workload and programme factors. Our study showcases the potential for sustainable volunteer CHW programming at scale and can inform planners and policymakers considering programme design, including selection and replacement planning for CHW networks.
Regulatory relationships of demographic, clinical characteristics and quality of care for heart failure patients in southern China
Authors: Fu Rong , Feng Shaodan , Chen Qidong , Lin Yulan , Lin Zheng , Hu Zhijian 
Published: December 2021

AbstractObjectiveQuality of care for Chinese patients with heart failure was substandard. This study aimed to ascertain the characteristics related to quality of care to narrow the gap.MethodsData from 2064 heart failure patients between 1 January 2012 and 31 December 2015 at a hospital in Fujian Province were analyzed. The Bayesian network was used to assess the regulatory relationships between demographic and clinical characteristics and compliance with quality indicators.ResultsThe compliance with quality indicators ranged from 42.5% to 90.2%. The compliance with recommended doses for medications all reached or was close to 100% except indapamide. Residence place, hypertension, troponin, B-type natriuretic peptide, heart rate, lung disease, number of emergency treatments (ETs) and ejection fraction directly regulated the compliance, and gender, age, medical payment methods, myocardiopathy, coronary heart disease and arrhythmia indirectly regulated the compliance in the Bayesian network. The lower compliance was found in patients under ET, patients with abnormal testing indicators, patients without specific comorbidities and patients under the New Rural Cooperative Medical Scheme or self-paying. Patients with lung disease and those who lived in urban areas had a longer length of stay.ConclusionsThe compliance with medication indicators for heart failure was suboptimal, but recommended doses were prescribed to patients who received medications. A series of strategies should be developed to improve the quality of care, such as expanding the scope and depth of knowledge of guidelines and clinical pathways, integrating the reminder and quality assessment model into the hospital medical record information system, paying more attention to the vulnerable population and improving the medical security system.
Effects of a blend of essential oils, medium-chain fatty acids, and a toxin-adsorbing mineral on diarrhea and gut microbiome of weanling pigs experimentally infected with a pathogenic Escherichia coli
Authors: He Yijie , Jinno Cynthia , Li Chong , Johnston Sara L , Xue Hongyu , Liu Yanhong , Ji Peng 
Published: December 2021

Abstract
A proprietary antimicrobial feed additive comprised of essential oils, medium-chain fatty acids, and a toxin-adsorbing mineral showed promising bacteriostatic and bactericidal effects in vitro. This study investigated the impacts of supplementing this blend on growth, gut microbiome, and enteric disease resilience in weaned pigs experimentally challenged with an enterotoxigenic Escherichia coli (ETEC). Thirty-six weanling pigs (6.88 ± 0.30 kg body weight) blocked by weight and gender were assigned to one of three dietary treatments: control or dietary supplementation with 0.25% or 0.50% of the antimicrobial blend. This study lasted 28 d with 7 d before and 21 d after the first ETEC inoculation (day 0). All pigs were orally inoculated with 1010 CFU F18 + ETEC/3-mL dose for 3 consecutive days. Growth performance data and diarrhea scores were recorded throughout the experiment. Fecal samples collected on days −7, 0, 7, and 21 post first inoculation (PI), and ileal digesta and mucosal tissue collected on day 21 PI were further analyzed for gut microbiome using 16S rRNA sequencing. All data, except for frequency of diarrhea and gut microbiome, were analyzed by ANOVA using the PROC MIXED of SAS. The chi-square test was used for analyzing frequency of diarrhea. Gut microbiome data were analyzed using QIIME2 and visualized using the R program. Dietary supplementation of 0.25% or 0.5% of the antimicrobial blend increased (P &lt; 0.05) feed efficiency on days 14 to 21 PI of ETEC and reduced (P &lt; 0.05) frequency of diarrhea during the study. Compared with the control group, adding 0.5% dietary antimicrobial blend increased (P &lt; 0.05) relative abundance of Firmicutes but reduced (P &lt; 0.05) Bacteroidetes and Proteobacteria in feces on day 7 PI. Pigs that received the antimicrobial blend also had higher (P &lt; 0.05) relative abundance of Lactobacillaceae, but lower (P &lt; 0.05) relative abundance of Enterobacteriaceae in feces on day 7 PI than pigs in control. In conclusion, supplementation of this antimicrobial blend at 0.5% reduced incidence of severe diarrhea in weaned pigs challenged with F18 ETEC and enhanced feed efficiency of weaned pigs at the last week of the experiment. Supplementation of this antimicrobial blend also modified the microbiota diversity in feces and ileal mucosa of weaned pigs.