bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cascading impacts of earthquakes and extreme heatwaves have destroyed populations of an iconic marine foundation species
Authors: Thomsen Mads S. , Mondardini Luca , Thoral François , Gerber Derek , Montie Shinae , South Paul M. , Tait Leigh , Orchard Shane , Alestra Tommaso , Schiel David R. 
Published: September 2021

AbstractAimEcologists traditionally study how contemporary local processes, such as biological interactions and physical stressors, affect the distribution and abundance of organisms. By comparison, biogeographers study the distribution of the same organisms, but focus on historic, larger‐scale processes that can cause mass mortalities, such as earthquakes. Here we document cascading effects of rare biogeographical (seismic) and more common ecological (temperature‐related) processes on the distribution and abundances of coastal foundation species.LocationIntertidal wave‐exposed rocky reefs around Kaikōura, New Zealand, dominated by large, long‐lived, and iconic southern bull kelps (Durvillaea antarctica and Durvillaea willana).MethodsIn November 2016, a 7.8 Mw earthquake uplifted the coastline around Kaikōura by up to 2 m, and a year later the region experienced the hottest summer on record. Extensive sampling of intertidal communities over 15 km coastline were done shortly after the earthquake and heatwaves and 4 years after the earthquake.ResultsDurvillaea lost 75% of its canopy to uplift and the heatwaves reduced canopies that had survived the uplift by an additional 35%. The survey done 4 years after the earthquake showed that Durvillaea had not recovered and that the intertidal zone in many places now was dominated by small turfs and foliose seaweed.Main conclusionsCascading impacts from seismic uplift and heatwaves have destroyed populations of Durvillaea around Kaikōura. Surviving smaller and sparser Durvillaea patches will likely compromise capacity for self‐replacement and lower resilience to future stressors. These results are discussed in a global biogeographical‐ecological context of seismic activity and extreme heatwaves and highlight that these events, which are not particularly rare in a geological context, may have common long‐lasting ecological legacies.
Learners’ satisfaction with web‐based assessment platforms
Authors: Merhi Mohammad I. , Meisami Alex 
Published: August 2021

AbstractThis study examines the factors that impact learners’ satisfaction with web‐based assessment platforms designed by publishers. The research model investigates the intermediate role of autonomy and competency from the self‐determination theory. The data are collected from 324 undergraduate business students in a mid‐western U.S. institution who used McGraw‐Hill Connect. The hypotheses were tested and validated using PLS‐SEM analytical procedures. The results show that competency, autonomy, perceived quality, and feedback have direct impact on learners’ satisfaction. Self‐efficacy, quality, and feedback are antecedents to competency and autonomy. Competency is a full mediator between self‐efficacy and satisfaction. The results and their implications are discussed.
COVID‐19 and exacerbation of dermatological diseases: A review of the available literature
Authors: Aram Khashayar , Patil Anant , Goldust Mohamad , Rajabi Fateme 
Published: August 2021

AbstractSince the emergence of the new coronavirus disease 19 (COVID‐19) pandemic, there has been a concern for the patients with chronic autoimmune diseases including dermatological conditions over the potential exacerbation of these underlying conditions after infection with severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV2). We performed a systematic review to evaluate presentations, postinfection change in the manifestation, diagnosis, and management of flare‐ups of underlying dermatologic disease in patients with COVID‐19. A total of 17 articles were recovered reporting on flare‐ups of dermatological disease including pemphigus vulgaris, psoriasis, subacute cutaneous lupus erythematosus, acrodermatitis continua of Hallopeau, systemic sclerosis sine scleroderma, and Sézary syndrome (SS). Out of these, psoriasis and alopecia areata were the most common conditions. However, most cases of psoriasis could have been attributed to either antimalarial agents that were initially used for the treatment of COVID‐19 or discontinuation of treatment following SARS‐CoV2 infection.
Biotic interactions are more often important at species’ warm versus cool range edges
Authors: Paquette Alexandra , Hargreaves Anna L. 
Published: August 2021

AbstractPredicting which ecological factors constrain species distributions is a fundamental ecological question and critical to forecasting geographic responses to global change. Darwin hypothesised that abiotic factors generally impose species’ high‐latitude and high‐elevation (typically cool) range limits, whereas biotic interactions more often impose species’ low‐latitude/low‐elevation (typically warm) limits, but empirical support has been mixed. Here, we clarify three predictions arising from Darwin's hypothesis and show that previously mixed support is partially due to researchers testing different predictions. Using a comprehensive literature review (885 range limits), we find that biotic interactions, including competition, predation and parasitism, contributed to >60% of range limits and influenced species’ warm limits more often than cool limits. Abiotic factors contributed more often than biotic interactions to cool range limits, but temperature contributed frequently to both cool and warm limits. Our results suggest that most range limits will be sensitive to climate warming, but warm‐limit responses in particular will depend strongly on biotic interactions.
How do street‐level bureaucrats manage high workloads? Collegial mechanisms at the organisational level—experiences from public healthcare organisations
Authors: Berlin Johan , Szücs Stefan , Höjer Staffan , Liljegren Andreas 
Published: September 2021

AbstractThe aim of this study is to understand and explain how street‐level bureaucrats manage high workloads in public healthcare organisations. Data was collected through observations, interviews and documents. The results show that high workloads are reduced through use of collegial mechanisms at the organisation level. The study shows that workloads are reduced in a two‐step process, the first is a negotiation between professionals and the second in the meeting with patients. The two‐step process explains the limitation problems in more detail and makes an important contribution by explaining how high workloads are reduced in public health services.
Corpus callosum hypersignals and focal atrophy: Neuroimaging findings in globular glial tauopathy type I
Authors: Keller Jiri , Kavkova Anna , Matej Radoslav , Cséfalvay Zsolt , Rusina Robert 
Published: September 2021

AbstractBackground and purposeGlobular glial tauopathies (GGTs) have heterogeneous presentations; little evidence regarding typical clinical and magnetic resonance imaging (MRI) presentations are available.MethodsWe retrospectively assessed MRIs from three postmortem‐confirmed GGT cases, in two patients with atypical progressive aphasia and one with corticobasal syndrome.ResultsWe suggest that four principal concomitant MRI findings characterize GGT type I: a sagittal callosal hyperintense band, marked focal callosal atrophy suggesting white matter degeneration originating in cortical areas responsible for symptoms (anterior atrophy in predominantly language manifestations and posterior atrophy in predominantly apraxia), periventricular white matter lesions, and mild‐to‐moderate brain stem atrophy.ConclusionsWe observed four concomitant MRI abnormalities in patients with atypical dementia, parkinsonism, and late incomplete supranuclear gaze palsy. Two patients had atypical progressive aphasia and one had corticobasal syndrome.
From southern swamps to cosmopolitan model: Humanity’s unfinished history with mosquitofish
Authors: Fryxell David C. , Moffett Emma R. , Kinnison Michael T. , Simon Kevin S. , Palkovacs Eric P. 
Published: September 2021

AbstractThe most widespread and numerous inland fish in the world is likely the mosquitofish (Gambusia affinisandG. holbrooki, Poeciliidae). Much has been written about the basic biology, the current distribution and the negative impacts of non‐native populations of mosquitofish. Here, we instead review the relationship of humanity with mosquitofish. First, we review the early literature on the species and aim to resolve its path towards becoming the globally dominant fish for biological control of mosquitoes. We identify the initial advocates of mosquitofish use, we examine the reasons behind their advocacy, and we document the spread of their viewpoints into and from the globally foundational mosquito control texts. Second, we identify the people and institutions that facilitated early international translocations of mosquitofish, including, among others, David Starr Jordan, the Rockefeller Foundation and the International Red Cross. Third, we discuss the reduction in mosquitofish translocation and use during and after WWII, initially stemming from the discovery and use of other methods, like DDT and later from a recognition of the negative ecological consequences of non‐native mosquitofish populations. Fourth, we propose that the future utility of mosquitofish is largely in its value as a model study organism. We provide an overview of the contributions mosquitofish have made to some major fields in biology. Finally, we suggest that the value of mosquitofish as a model system should increase into the future, behind a momentum of research advances, and as human‐mediated range expansion will permit access to mosquitofish by yet greater numbers of biologists worldwide.
Credit derivatives and loan yields
Authors: Azam Nimita , Mamun Abdullah , Tannous George F. 
Published: September 2021

AbstractWe compare the loan yields of credit derivative (CRD) active bank holding companies (BHCs) with the loan yields of CRD inactive peers over the pre‐crisis, crisis (2008–10), and post‐crisis periods. During the post‐crisis period, protection purchasers report lower yields than their peers, while sellers report yields like those reported by their peers. The relation between the yield and commercial and industrial (C&I) loans is positive and significant during the pre‐ and post‐crisis periods, and CRD activities do not affect this relation. CRD activities are changing the relations between the loan yield and consumer loans, real estate loans, and securitization.
Infection prevention and control practice among home‐care nursing agencies in Japan: Secondary analysis of a nationwide cross‐sectional survey
Authors: Morioka Noriko , Kashiwagi Masayo 
Published: September 2021

AimWe describe the nationwide situation of infection prevention and control (IPC) practices among home‐visit nursing agencies and compare them by agency size to explore whether these practices are associated with the occurrence of infection.MethodsWe conducted a secondary analysis using data from a cross‐sectional nationwide survey inspecting patient safety and IPC practices among nationwide home‐visit nursing agencies, from March to April 2020. Among 9978 agencies, 580 responded and 370 were incorporated in the analysis. The self‐administered questionnaire inquired about the IPC policy and administrative structure, education and training, adherence to standard precautions, and employee health programs. We described the adherence to IPC practice at the agency level and compared them by agency size using chi‐squared tests. Logistic regression analysis was performed to explore the associations between IPC practices and incidence of infection.ResultsAdherence to IPC practices ranged from 19.2% to 92.4% and varied according to agency size. Less than 20% of agencies had instituted a committee for IPC and strictly used disposable aprons when changing patients' diapers. Instituting a committee for IPC (odds ratio 2.19, 95% confidence interval 1.11–4.34, P < 0.05) and training staff for infection prevention (odds ratio 1.67, 95% confidence interval 1.02–2.72, P < 0.01) were significantly associated with the incidence of infection, after adjusting for covariates.ConclusionsThere are challenges in establishing IPC policies and administrative structures and adhering to standard precautions. Well‐organized agencies were found to be more likely to detect infections occurring over the past 3 months. Geriatr Gerontol Int 2021; 21: 913–918.
Is there heterogeneity among persistent high‐growth firms?
Authors: Monteiro Guilherme Fowler A. , Bortoluzzo Adriana Bruscato , Rosa Pedro Lipkin P. 
Published: September 2021

AbstractTheoretical and empirical studies on persistent high growth have largely focused on the extent to which companies are able to sustain their high growth rates over time and whether there are firm‐level determinants of this behavior. These studies, however, neglect the question of whether persistent high‐growth firms exhibit distinct growth patterns. To analyze this question empirically, we examine a database of approximately 16,000 persistently high‐growth companies located in Brazil during the period 2013–2016. First, we develop a clustering analysis, finding three high‐growth patterns. Based on this classification, and through ordered logit regression, we then examine whether regional dimensions explain the differences in growth. The results indicate that companies located in regions with more availability of technological, educational, and physical infrastructure are more likely to be in the groups with the highest growth. On the other hand, the increase in regional sophistication in economic terms tends to reduce the likelihood of very high growth. This specific result is confirmed when we perform quantile regressions.
Structured medicines reviews in HIV outpatients: a feasibility study (The MOR Study)
Authors: Leake Date Heather A. , Alford Katie , Hounsome Natalia , Moore David , Ing Kin , Vera Jaime H. 
Published: September 2021

AbstractObjectivesPolypharmacy in people living with HIV (PLWH) increases the risks of medicine‐related problems (events or circumstances involving drug therapy that actually or potentially interfere with desired health outcomes). We aimed to examine the feasibility and acceptability of a Medicines Management Optimisation Review (MOR) toolkit in HIV outpatients.MethodsThis was a multi‐centre randomized controlled study across four HIV centres. In all, 200 PLWH on combination antiretroviral therapy, either > 50 years old or < 50 years with other comorbidities, were enrolled to have a MOR or received standard pharmaceutical care. The primary outcome was the difference in the number of medicine‐related problems (MRPs) between intervention and standard care groups at baseline and 6 months. Acceptability, cost of the intervention and health‐related quality of life were also examined.ResultsIn all, 164 patients were analysed: 70 in the intervention group and 94 in the standard care group. A significant number of MRPs were detected in those patients receiving MOR compared with the standard care group at baseline (93 vs. 2; p = 0.001, z = −8.6, r = 0.6) and 6 months (33 vs. 3; p = 0.001, z = −5.7, r = 0.4). A significant reduction in the number of new MRPs at 6 months in the intervention group versus baseline was also observed (p = 0.001, Z = −3.7, r = 0.2); 44% of MRPs were fully resolved at baseline and 51% at 6 months. No changes in health‐related quality of life following MOR or between MOR and standard care groups were observed. The MORs were highly acceptable among patients and healthcare professionals.ConclusionsThe MOR toolkit was feasible and acceptable, suggesting that HIV outpatient services might consider implementing MOR for targeted populations under their care.
Pharmacological inhibition of USP7 suppresses growth and metastasis of melanoma cells in vitro and in vivo
Authors: Xiang Minmin , Liang Long , Kuang Xinwei , Xie Zuozhong , Liu Jing , Zhao Shuang , Su Juan , Chen Xiang , Liu Hong 
Published: September 2021

AbstractMelanoma is a highly aggressive type of skin cancer. The development of diverse resistance mechanisms and severe adverse effects significantly limit the efficiency of current therapeutic approaches. Identification of the new therapeutic targets involved in the pathogenesis will benefit the development of novel therapeutic strategies. The deubiquitinase ubiquitin–specific protease‐7, a potential target for cancer treatment, is deregulated in types of cancer, but its role in melanoma is still unclear. We investigated the role and the inhibitor P22077 of ubiquitin‐specific protease‐7 in melanoma treatment. We found that ubiquitin‐specific protease‐7 was overexpressed and correlated with poor prognosis in melanoma. Further, pharmacological inhibition of ubiquitin‐specific protease‐7 by P22077 can effectively inhibit proliferation, and induce cell cycle arrest and apoptosis via ROS accumulation–induced DNA damage in melanoma cells. Inhibition of ubiquitin‐specific protease‐7 by P22077 also inhibits melanoma tumour growth in vivo. Moreover, inhibition of ubiquitin‐specific protease‐7 prevented migration and invasion of melanoma cells in vitro and in vivo by decreasing the Wnt/β‐catenin signalling pathway. Taken together, our study revealed that ubiquitin‐specific protease‐7 acted as an oncogene involved in melanoma cell proliferation and metastasis. Therefore, ubiquitin‐specific protease‐7 may serve as potential candidates for the treatment of melanoma.
One‐year follow‐up comparing at‐home bleaching systems outcomes and the impact on patient's satisfaction: Randomized clinical trial
Authors: Mailart Mariane C. , Sakassegawa Paula A. , Santos Karine C. , Torres Carlos R. G. , Palo Renato M. , Borges Alessandra B. 
Published: August 2021

AbstractObjectiveTo compare at‐home systems with reduced daily time of use (10% hydrogen peroxide [HP] gel with prefilled (PT) or customized trays (CT), and 10% carbamide peroxide [CP] gel), with the conventional nightguard vital bleaching (10% CP). Bleaching efficacy, adverse effects, and patient's satisfaction were evaluated.MethodsSixty participants were randomly divided into treatments (14 days): Opalescence GO (OGO)‐10%HP PT‐30 min, White Class‐10%HP CT‐30 min, Opalescence PF‐10%CP CT‐2 h, and Opalescence PF‐10%CP CT‐8 h. Color difference (visual and spectrophotometer), tooth sensitivity (visual analogue scale), gingival condition (Löe index), enamel mineralization (laser fluorescence), and patients' satisfaction (questionnaire) were assessed. Statistical tests were applied (5%).ResultsAfter 1 year, color difference was similar for the groups (p > 0.05). All groups showed similar sensitivity risk (p > 0.05). The intensity of sensitivity and gingival irritation was mild for all gels, but higher for OGO. Fluorescence after bleaching remained similar to those of sound enamel. All participants were satisfied with treatments.ConclusionsAll systems produced similar bleaching efficacy, which was maintained after 1 year. Patients were satisfied with bleaching outcomes. Tooth sensitivity occurred in all groups, but with overall mild intensity. No relevant gingival irritation and enamel demineralization was observed.Clinical significanceBleaching with 10% HP gels in prefilled and CTs represent efficacious alternative for tooth color change, with patients' acceptance similar to conventional 10% CP. Patients must be warned about the mild sensitivity and gingival irritation potential, mainly with PTs.
The double ABCM model of marital satisfaction
Authors: Hall Scott S. 
Published: September 2021

AbstractThe proposed double ABCM model of marital satisfaction draws from the double ABCX theory of family behavior framework to incorporate pre‐marital factors associated with getting married that carry‐over into the marriage itself; it also integrates marital demands, circumstances, and perceptions that ultimately contribute to marital satisfaction. Bodies of literature related to marriage intentions, marital beliefs, newlywed adjustment, and marital maintenance are integrated into the constructs of the model. The double ABCM model expands the structure of the original double ABCX framework in several ways, including by explicitly depicting broader contextual factors that influence intra‐relational processes, diagraming the shared and unshared aspects of most constructs, and illustrating a nonlinear passage of time. Limitations and implications are discussed.
Could standing orders have a place? A phenomenological exploration of experienced ward‐based registered nurses' views on the escalation protocol for patient deterioration
Authors: Minyaev Stanislav , Harrington Ann , King Lindy 
Published: September 2021

AbstractAims and objectivesTo explore experienced ward‐based Registered Nurses’ views on the potential use of standing orders, prior to the escalation protocol, for patient deterioration.BackgroundWard based nurses are required to follow set steps of the escalation protocol. The introduction of standing order policies would allow nurses to intervene earlier when deterioration was first detected.DesignHermeneutic Phenomenology.MethodsTen experienced ward‐based RNs were recruited. Semi‐structured interviews were conducted, with the data subjected to thematic analysis. Diekelmann's framework was used to analyse the texts, seeking the highest level of hermeneutic analysis namely, a constitutive pattern. COREQ guidelines were utilised.ResultsFour main themes emerged: (1) Ambiguity in perception: the escalation protocol; (2) Observations within acceptable parameters, but the patient is deteriorating; (3) Paradoxes of escalation: well laid out protocol, but hard to escalate; (4) We could intervene with standing orders, but are we permitted? The constitutive pattern namely, Dualism in Perception related to the dissonance conveyed by participants regarding the escalation protocol.ConclusionsNotwithstanding the benefits of the escalation protocol for junior staff, the RNs offered critique of the established escalation practices and the restrictive role of the protocol. Another aspect of the protocol, that is ‘worried criterion’ was viewed positively. The participants expressed a desire to apply nurse‐driven standing orders, to enable them to intervene earlier for patient deterioration.Relevance to clinical practiceOrganisations should consider new policies introducing standing orders for implementation by experienced RNs. The engagement of experienced ward‐based nurses in forming ‘patient at‐risk teams’ could assist organisations to deal with cases of clinical deterioration prior to activation of the escalation of care protocol.