bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analytical Study of Remorse in Religious Texts in English and Arabic Languages
Authors: Hussein Ahmed Sultan , Abood Sameer Abdulrazak 
Published: April 2021

Remorse is a contrite emotion experienced by a person who regrets actions which are deemed to be hurtful, shameful, or violent. Presumably remorse in religion may be different from that of ordinary life. Furthermore, remorse linguistically manifests itself in different manners and behaviors (direct, indirect, declarative, and imperative). The permanent study confines itself within the religious texts in English and Arabic languages. The data chosen for this purpose are the Old testament of Bible as an English data and Al-Sahifa al Sajadia as an Arabic data. The study targets at showing how in religious text, the majority of remorse are realized in declarative rather than imperative or exclamation utterances though there is a chance for the last two options to occur. Furthermore, most Arabic religious remorse is identified in direct speech acts while English remorse is realized throughout indirect speech act. The study answers a set of empirical questions: 1-What makes remorse different from similar speech acts which seem outwardly the same but inwardly not, like; guilt, regret, repentance and other likes 2- What are the similarities and differences in both languages in question. An eclectic model is adopted for the analysis. The study illustrates that Remorse in religious language is not the same to that one of ordinary life since the former but not necessarily the latter targets repentance to be its own goal. Moreover there is a variation in the use of it in of both languages though there are some similarities. Arabic language proved to be profoundly richer than English. What distinguishes the former is the abundance of exclamation and imperative modes, the descriptive phrases, the direct speech acts besides the active voice and declarative mode which represent the similarities between the two languages.
English as a Foreign Language: Insights from a Public University in Bangladesh
Authors: Hossain Mohammad Afzal 
Published: April 2021

This study intends to examine the perspective of learners from a public university regarding English Language Teaching (ELT) syllabus and pedagogy. The learners in this study are studying Masters (MA) in ELT at Mawlana Bhashani Science and Technology University (MBSTU). MBSTU is a public university situated in Tangail, Bangladesh. Being their direct teacher, I thought it would be interesting to find out how my students are perceiving ELT courses, in fact the process of data collection and analysis has been an important learning experience for myself, allowing me to delve into the loopholes and strengths of the current ELT curriculum. The survey questionnaire was sent to thirty of the currently enrolled MA students but fourteen responses were obtained due to the current Corona virus pandemic situation. It is worthwhile to mention that this is the first cohort of students for the MA in ELT program at MBSTU. The MA in ELT program was introduced in the university in 2019. This study was conducted using a semi-structured questionnaire, and data was analyzed qualitatively. The findings from the study suggest that the students prioritize speaking English fluently and pronouncing English vocabulary correctly. The MA syllabus was highly commended by students as it focuses on pronunciation through the course of Phonetics and Phonology.
Can Futsugo be Acceptable in Hotel Services? A Case Study of a Hotel in Bali
Authors: Kusumarini Indah , Simpen I Wayan , Budiarsa Made , Laksana I Ketut Darma 
Published: April 2021

This article discusses futsugo (Japanese daily language). The aim of this research is to know whether Futsugo style can be used at hotel services. As we know that hotels are the main constituent of the hospitality industry which keep special attention to courtesy and services, so is it possible for the hotel staff to use it? Does it threaten guests' faces? The data analyzed is conversation instances between Japanese guests and hotel staff in Bali hotels. The sampling used is a random sampling technique. The sample used in the study is 10 hotels out of 73 five-star hotels in Bali. The conversation data is recorded with mobile phones by hotel staff. The total number of the hotel staff members as the subjects of this research is 15 participants. The data was conducted from May 2019 till August 2019. Brown and Levinson's (1987) politeness theory is used to analyze conversations between Japanese guests and hotel staff in Bali from the stages of arrival, familiarization, and engagement until departure. Based on data analysis, it is known that generally hotel staff use negative politeness strategies alternately with positive politeness strategies depending on the context of the speech situation. From these four those stages, it is found that Futsugo utterances are at the engagement stage. Futsugo style was used by the staff during handling guest complaints. In one dialogue, Futsugo's utterance was found in the form of question sentences without question marks, but using the rising intonation and confirmation of the guest’s answer without the copula desu. According to the analysis of the conversation data, futsugo utterances are used by hotel staff and guests as a practical way of communicating. Futsugo's utterances which tend to be short are easier to catch by the ear, making it easier to handle guest complaints. If viewed from the perspective of politeness theory, this speech can still be accepted. It can be seen from the whole conversation where negative politeness strategies and positive politeness strategies are applied in one dialogue that the appearance of Futsugo's utterances is still considered acceptable and does not threaten guests' faces.
Teacher Talk and Learner Involvement in EFL Classroom: The Case of Saudi Setting
Authors: Hamdan Ayman Hamad Elneil , Elandeef Elsadig Ali Elsadig 
Published: April 2021

This study investigates the maximum output of minimizing teacher talk and activating classroom interactivity in teaching English as a foreign language in light of 21st-century skills. It focuses on the self-evaluation of teacher talk (SETT model) and classroom interactional competence (CIC) that guides the teachers to use interaction as a tool to give their learners enough learning opportunities. Teacher talking time is analyzed from a dualistic perspective, quantity and quality. The classroom interaction's analysis is based on the micro contexts and the pedagogic aspects. This research is conducted with a qualitative approach and content analysis method. The data source is the recording of ten English classes at the college of sciences and arts in Dhahran Aljanoub, King Khalid University (KKU). The study's findings have revealed that instructors dominate talking in English class and pose questions to students to minimise teacher talking time, and the most interactional features are based on displaying questions and teachers' domination of English classroom discourse.
Challenges of Student-mothers in the Tertiary Education of University of Perpetual Help System-DALTA
Authors: Dasig Josephine Pineda 
Published: April 2021

This paper utilized phenomenological qualitative research to determine the lived experiences of ten students who are also mothers in pursuing their college education. The participants were identified using purposive sampling. The participants were screened using the following inclusion criteria: enrolled in any bachelor’s degree and had one or more children. The researcher used an informal interview as tool in gathering the data. Five themes emerged from the participants’ data: the meaning of a woman and a mother, becoming young mothers, the importance of fulfilling their dreams, the challenges and difficulties they faced in their studies, and the effect of schooling in their life. All participants believed that women are strong in facing the adversities in life. On the other hand, mothers to the participants need not depend on men to support their children. The participants also likened the word mother to love and sacrifice. The lived experiences of these student-mothers won my admiration for they live their life to the fullest by becoming good mothers at the same time good students.
Usefulness of GeneXpert MTB/RIF in the diagnosis of extra-pulmonary tuberculosis
Authors: Islam Nasreen , Hossain Mohammad Delwar , Rahim Muhammad Abdur , Ahmed Jamal Uddin , Amin Muhammad Kamrul , Afroz Farhana 
Published: April 2021

Background: Diagnosis of extra-pulmonary tuberculosis (TB) is often delayed because of diverse clinical presentations and difficulties in establishing the bacteriological diagnosis. This study aimed to evaluate usefulness of GeneXpert MTB/RIF in the diagnosis of extra-pulmonary TB in Bangladeshi patients.
Methods: This cross-sectional study was done in BIRDEM General Hospital, Dhaka, Bangladesh from 2013 to 2016 as a part of Bangladesh Diabetic Somiti (BADAS)-USAID-TB Care-II project. Representative samples from 590 clinically suspected extra-pulmonary TB cases were tested for GeneXpert MTB/RIF along with conventional methods.
Results: Total patients were 590 [mean age 43.9 (range 1-95) years] with male predominance (326, 55.3%). Most (513, 86.9%) patients were diabetic and new (574, 97.3%) TB suspects; while 16 (2.7%) patients had past history of TB. Common samples were pleural fluid (125, 21.2%), urine (110, 18.6%), cerebrospinal fluid (CSF) (91, 15.4%), pus (82, 13.9%), tracheal aspirates (57, 9.7%), ascitic fluid (45, 7.6%), gastric lavage (31, 5.3%), broncho-alveolar lavage (BAL) (18, 3.1%), lymph node aspirates (11, 1.9%) and synovial fluid (8, 1.4%). Among 590 samples, 68 (11.5%) were positive for Mycobacterium tuberculosis. Diagnostic yield was common for lymph nodes (4/7, 57.1%), pus (25/82, 30.5%), BAL (4/18, 22.2%), tracheal aspirates (8/57, 14.0%), urine (7/110, 6.4%), CSF (6/91, 6.6%) and pleural fluid (7/125, 5.6%). Of the 68 GeneXpert MTB/RIF positive samples, 52 (76.1%) were rifampicin sensitive, 16 (23.9%) showed intermediate sensitivity and none of the samples was resistant to rifampicin.
Conclusions: GeneXpert MTB/RIF appeared as useful tool for diagnosing extra-pulmonary TB.
Birdem Med J 2021; 11(2): 121-124
Acute pulmonary embolism complicating deep vein thrombosis in a young patient with stroke
Authors: Rahman Mohammed Mirazur , Habib Farjana Binte , Kabir Ahmed Imran , Islam Samprity , Chakrabortty Rajashish , Hossain AKM Mosharraf 
Published: April 2021

Acute pulmonary embolism is one of the most common causes of vascular death after myocardial infarction and cerebrovascular accidents. It usually presents with severe chest pain and shortness of breath and occasionally occurs in the background of deep vein thrombosis. A 32-year-old male presented with swelling of left lower limb and shortness of breath. Subsequent investigations revealed that he developed DVT of left lower limb and pulmonary embolism. However, in general, if left untreated, pulmonary embolism is associated with an overall mortality of up to 30 percent compared with 2 to 11 percent in those treated with anticoagulation. Early diagnosis by D-dimer, computed tomograpgy pulmonary angiogram and doppler study of the left lower limb and prompt intervention through low molecular weight heparin and rivaroxaban led to a successful outcome in our case.
Birdem Med J 2021; 11(2): 142-144
Hemodynamic Parameters Predict In-stent Thrombosis After Multibranched Endovascular Repair of Complex Abdominal Aortic Aneurysms: A Retrospective Study of Branched Stent-Graft Thrombosis
Authors: Liu Ming-Yuan , Jiao Yang , Liu Junjun , Zhang Simeng , Li Wei 
Published: April 2021

Background: Branch vessel occlusion is reported in endovascular repair of aortic pathology. This study aimed to evaluate the hemodynamic indicators associated with in-stent thrombosis (IST) of a branched stent-graft (BSG) after endovascular aortic repair (EVAR) of a complex abdominal aortic aneurysm.Methods: A retrospective evaluation was performed based on the computed tomography (CT) scans and clinical data of three patients who underwent multi-branched endovascular repair. Patient-specific 3-dimensional models were reconstructed, and hemodynamic analysis was performed for IST. Hemodynamics-related parameters including time-averaged wall shear stress (TAWSS), oscillatory shear stress index (OSI), and relative residence time (RRT) were compared among the individual patients.Results: The flow velocity, TAWSS, OSI, and RRT were radically changed in the area of the IST. In BSGs, IST tended to occur in the regions of hemodynamic alteration near the bends in the device, where a decreased flow velocity (&lt;0.6 m/s) and TAWSS (&lt;0.8 Pa) and an elevated OSI (&gt;0.2) and RRT (&gt;5 s) were consistently observed.Conclusions: Hemodynamic perturbations in BSGs cause a predisposition to IST, which can be predicted by a series of changes in the flow parameters. Early hemodynamic analysis might be useful for identifying and remediating IST after multibranched endovascular repair.
Effect of Day 3 and Day 5/6 Embryo Quality on the Reproductive Outcomes in the Single Vitrified Embryo Transfer Cycles
Authors: Wang Ningling , Zhao Xinxi , Ma Meng , Zhu Qianqian , Wang Yao 
Published: April 2021

ObjectiveTo explore the live birth rate and neonatal outcome after single vitrified blastocyst transfer versus single vitrified cleavage-stage embryo transfer at different grades of embryo quality.MethodsA retrospective cohort study including 6077 single vitrified-thawed embryo transfer cycles was performed in the time-period from January 2013 to December 2018.ResultsAfter controlling for potential confounding variables, there are 161% increased odds of a live birth after transfer of single good quality embryo at day 5, 152% increased odds of a live birth after transfer of single poor quality embryo at day 5, 60% increased odds of a live birth after transfer of single good quality embryo at day 6 compared with transfer of single good quality embryo at day 3. Results from the generalized estimated equation regression showed significant relationship of unadjusted birth weight with development stage of embryo and embryo quality (good quality embryo on day 5 vs. Good quality embryo on day 3:β=108.55, SE=34.89, P=0.002; good quality embryo on day 6 vs. Good quality embryo on day 3:β=68.80, SE=33.75, P=0.041). However, no significant differences were seen in birth weight between transfer single poor quality embryo on day 5, 6 and transfer single good quality embryo on day 3.ConclusionA significant increase in live birth rate and birth weight after transfer of single good quality embryo on day 5 and day 6 compared with transfer of single good quality embryo on day 3 in the vitrified embryo transfer cycles.
The 5-HTTLPR-rs25531 S-A-S-A Haplotype and Chronic Stress Moderate the Association Between Acute Stress and Internalizing Mental Disorders Among HIV+ Children and Adolescents in Uganda
Authors: Kalungi Allan , Womersley Jacqueline S. , Kinyanda Eugene , Joloba Moses L. , Ssembajjwe Wilber , Nsubuga Rebecca N. , Seedat Soraya , Hemmings Sian M. J. 
Published: April 2021

Background: Internalizing mental disorders (IMDs) among HIV-positive (HIV+) children and adolescents are associated with poor disease outcomes, such as faster HIV disease progression. Although it has been suggested that the development of IMDs is moderated by interaction of stressful life events and vulnerability factors, the underlying etiology is largely unknown. Serotonin transporter gene [solute carrier family 6 member A4 (SLC6A4)] and human tryptophan hydroxylase 2 gene (TPH2) polymorphisms have been implicated in the development of IMDs. This study investigated the association between acute stress and IMDs, and moderation by chronic stress and genetic variants in SLC6A4 and TPH2.Hypothesis: Acute stress acts through genetic and environmental vulnerability factors to increase the risk of developing IMDs.Methods: Polymorphisms in SLC6A4 (5-HTTLPR, rs25531, 5-HTTLPR-rs25531, and STin2 VNTR) and TPH2 (rs1843809, rs1386494, rs4570625, and rs34517220) were genotyped in 368 HIV+ children and adolescents (aged 5–17 years) with any internalizing mental disorder (depression, anxiety disorders, or posttraumatic stress disorder), and 368 age- and sex-matched controls, who were also HIV+. Chronic and acute stress categories were derived by hierarchical cluster analysis. Logistic regression analysis was used to assess the independent moderating effect of chronic stress and each selected polymorphism on the association between acute stress and IMDs.Results: We observed a statistically significant association between severe acute stress and IMDs (p = 0.001). Children and adolescents who experienced severe acute stress were twice as likely to develop IMDs, compared to children and adolescents who experienced mild acute stress (p = 0.001). Chronic stress interacted with severe acute stress to increase the risk of IMDs (p = 0.033). Acute stress was found to interact with 5-HTTLPR-rs25531 S-A-S-A haplotype to increase the risk for IMDs among Ugandan HIV+ children and adolescents (p = 0.049). We found no evidence for a combined interaction of acute stress, chronic stress, and 5-HTTLPR-rs25531 on IMDs.Conclusion: The odds of having an internalizing mental disorder (IMD) were higher among HIV+ children and adolescents who experienced severe acute stress compared to HIV+ children and adolescents who experienced mild acute stress. Chronic stress and 5-HTTLPR-rs25531 independently moderated the association between acute stress and IMDs.
Immune Response of Indian Preterm Infants to Pentavalent Vaccine Varies With Component Antigens and Gestational Age
Authors: Kulkarni-Munje Archana , Malshe Nandini , Palkar Sonali , Amlekar Aniket , Lalwani Sanjay , Mishra Akhilesh Chandra , Arankalle Vidya 
Published: April 2021

Childhood vaccination plays critical role in protecting infants from several dreaded diseases. Of the global 15 million preterm (PT) infants with compromised immune system born annually, India contributes to &gt;3.5 million. Generation of adequate vaccine-induced immune response needs to be ensured of their protection. Immune response of Indian PT (n = 113) and full-term (FT, n = 80) infants to pentavalent vaccine administered as per the national recommendation was studied. Antibody titers against component antigens of pentavalent vaccine, immune cells profiling (T and B cells, monocytes and dendritic cells) and plasma cytokines were determined pre- and post-vaccination. Additionally, cell-mediated recall immune responses to pentavalent antigens were evaluated after short time antigenic exposure to infant PBMCs. Irrespective of gestational age (GA), all the infants developed adequate antibody response against tetanus, diphtheria, and protective but lower antibody levels for Haemophilus influenzae type-b and hepatitis B in preterm infants. Lower (~74%) protective antibody response to pertussis was independent of gestational age. PT-infants exhibited lower frequencies of CD4 T cells/dendritic cells/monocytes, increased plasma IL-10 levels and lower proliferation of central and effector memory T cells than in term-infants. Proliferative central memory response of FT-infants without anti-pertussis antibodies suggests protection from subsequent infection. Responder/non-responder PT-infants lacked immunological memory and could be infected with Bordetella. For hepatitis B, the recall response was gestational age-dependent and antibody status-independent. Humoral/cellular immune responses of PT-infants were dependent on the type of the immunogen. Preterm infants born before 32 weeks of gestation may need an extra dose of pentavalent vaccine for long lived robust immune response.
From the Immune Profile to the Immunoscore: Signatures for Improving Postsurgical Prognostic Prediction of Pancreatic Neuroendocrine Tumors
Authors: Wei Miaoyan , Xu Jin , Hua Jie , Meng Qingcai , Liang Chen , Liu Jiang , Zhang Bo , Wang Wei , Yu Xianjun , Shi Si 
Published: April 2021

ObjectiveImmune infiltration plays an important role in tumor development and progression and shows promising prognostic value in numerous tumors. In this study, we aimed to identify the role of immune infiltration in pancreatic neuroendocrine tumors (Pan-NETs) and to establish an Immunoscore system to improve the prediction of postsurgical recurrence-free survival.MethodsTo derive transcriptional signatures and deconvolute specific immune populations, two GEO datasets containing 158 Pan-NET patients were reanalyzed to summarize the immune infiltration landscape and identify immune-related signatures. Using real-time reverse transcription-polymerase chain reaction, immunofluorescence and immunochemistry methods, candidate signatures were further detected. The least absolute shrinkage and selection operator (LASSO) logistic regression model used statistically significant survival predicators in the training cohort (n=125) to build an Immunoscore system. The prognostic and predictive accuracy was validated in an external independent cohort of 77 patients.ResultsThe immune infiltration profile in Pan-NETs showed significant heterogeneity, among which accumulated immune cells, T lymphocytes and macrophages were predominant. Fourteen statistically significant immune-related signatures were further identified in the screening cohort. The Immunoscore system for Pan-NETs (ISpnet) consisting of six immune features (CCL19, IL-16, CD163, IRF4, CD8PT and CD8IT) was constructed to classify patients as high and low risk in the training cohort (cutoff value = 2.14). Low-risk patients demonstrated longer 5-year recurrence-free survival (HR, 0.061; 95% CI, 0.026 to 0.14; p &lt; 0.0001), with fewer recurrences and better prognoses. To predict the individual risk of recurrence, a nomogram incorporating both immune signatures and clinicopathological characteristics was developed.ConclusionOur model, ISpnet, captures immune feature-associated prognostic indicators in Pan-NETs and represents the first immune feature-based score for the postsurgical prognostic prediction. The nomogram based on the ISpnet and independent clinical risk factors might facilitate decision-making regarding early recurrence risk monitoring, identify high-risk patients in need of adjuvant therapy, and provide auxiliary guidance for patients with Pan-NETs that may benefit from immunotherapy in clinical trials.