bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimized LMS algorithm for system identification and noise cancellation
Authors: Ling Qianhua , Ikbal Mohammad Asif , Kumar P. 
Published: March 2021

Abstract
Optimization by definition is the action of making most effective or the best use of a resource or situation and that is required almost in every field of engineering. In this work, the optimization of Least Mean square (LMS) algorithm is carried out with the help of Particle Swarm Optimization (PSO) and Ant Colony Optimization (ACO). Efforts have been made to find out the advantages and disadvantages of combining gradient based (LMS) algorithm with Swarm Intelligence SI (ACO, PSO). This optimization of LMS algorithm will help us in further extending the uses of adaptive filtering to the system having multi-model error surface that is still a gray area of adaptive filtering. Because the available version of LMS algorithm that plays an important role in adaptive filtering is a gradient based algorithm, that get stuck at the local minima of system with multi-model error surface considering it global minima, resulting in an non-optimized convergence. By virtue of the proposed method we have got a profound solution for the problem associated with system with multimodal error surface. The results depict significant improvements in the performance and displayed fast convergence rate, rather stucking at local minima. Both the SI techniques displayed their own advantage and can be separately combined with LMS algorithm for adaptive filtering. This optimization of LMS algorithm will further help to resolve serious interference and noise issues and holds a very important application in the field of biomedical science.
Is Vision C interchangeable with the modified Westergren method for the erythrocyte sedimentation rate?
Authors: Erdogan Serpil , Firat Ridvan , Avcioglu Gamze , Yilmaz Gulsen , Erel Ozcan , Yilmaz Fatma Meric 
Published: March 2021

Abstract

Objectives
As one of the most widely used tests, the erythrocyte sedimentation rate (ESR) is a measurement of sedimentation reaction in blood samples. Although the recommended method for ESR measurement is the Westergren method, this method has some disadvantages in comparison with automated ESR systems. In this cross-sectional study, we aimed to compare Vision C with the Westergren method.

Methods
The Vision C automated ESR system and the modified Westergren method were compared using K3EDTA-containing tubes and citrated blood tubes from randomly selected 100 patients. Precision, bias, and interference calculations were performed.

Results
The mean difference between the Vision C (room temperature) and the modified Westergren method was 22.8 ± 26.6 mm/h (95% CI for the mean was 17.50–28.08 mm/h). The mean difference between the Vision C (18 °C) and the modified Westergren method was 27.4 ± 30.6 mm/h (95% CI for the mean was 21.3–33.5 mm/h). The calculated regression analysis equation was “y= 0.263 + 1.053x” and “y= −0.530 + 0.851x” for the Vision C (room temperature) and the Vision C (18 °C), respectively. The imprecision values ranged at 7.55–17.09%. According to our external quality control results, bias was 11.11 and 9.66 for the low- and high-level samples, respectively.

Conclusions
The Vision C automated ESR system has a comparable analytical performance with the modified Westergren method. The Vision C automated system may be utilized in ESR measurements with quality control evaluations. Nevertheless, temperature correction using Manley’s monogram causes an important negative bias and should be taken into consideration during the evaluation of the Vision C results.
Increased Hippocampal Excitability and Altered Learning Dynamics Mediate Cognitive Mapping Deficits in Human Aging
Authors: Diersch Nadine , Valdes-Herrera Jose P. , Tempelmann Claus , Wolbers Thomas 
Published: March 2021

Learning the spatial layout of a novel environment is associated with dynamic activity changes in the hippocampus and in medial parietal areas. With advancing age, the ability to learn spatial environments deteriorates substantially but the underlying neural mechanisms are not well understood. Here, we report findings from a behavioral and a fMRI experiment where healthy human older and younger adults of either sex performed a spatial learning task in a photorealistic virtual environment (VE). We modeled individual learning states using a Bayesian state-space model and found that activity in retrosplenial cortex (RSC)/parieto-occipital sulcus (POS) and anterior hippocampus did not change systematically as a function learning in older compared with younger adults across repeated episodes in the environment. Moreover, effective connectivity analyses revealed that the age-related learning deficits were linked to an increase in hippocampal excitability. Together, these results provide novel insights into how human aging affects computations in the brain's navigation system, highlighting the critical role of the hippocampus.SIGNIFICANCE STATEMENTKey structures of the brain's navigation circuit are particularly vulnerable to the deleterious consequences of aging, and declines in spatial navigation are among the earliest indicators for a progression from healthy aging to neurodegenerative diseases. Our study is among the first to provide a mechanistic account about how physiological changes in the aging brain affect the formation of spatial knowledge. We show that neural activity in the aging hippocampus and medial parietal areas is decoupled from individual learning states across repeated episodes in a novel spatial environment. Importantly, we find that increased excitability of the anterior hippocampus might constitute a potential neural mechanism for cognitive mapping deficits in old age.
Current Prescription Opioid Misuse and Suicide Risk Behaviors Among High School Students
Authors: Wilkins Natalie J. , Clayton Heather , Jones Christopher M. , Brown Melissa 
Published: March 2021

BACKGROUND AND OBJECTIVES:In previous studies, researchers have reported that youth with a lifetime history of prescription opioid misuse (POM) are at an increased risk for suicidal ideation, planning, and attempts. In this study, we investigate whether the association between youth POM and suicide outcomes differs by recency of POM (ie, none, past, or current misuse).METHODS:In this report, we use data from the 2019 Youth Risk Behavior Survey to examine associations between recency of POM (current POM, past POM, and no POM) and suicide risk behaviors among US high school students.RESULTS:After controlling for demographics, alcohol, and other drug use, both current POM and past POM were significantly associated with all suicide risk behaviors compared with no POM. Students who reported current POM had the highest adjusted prevalence ratios (aPRs) for suicidal ideation (aPR: 2.30; 95% confidence interval [CI] 1.97–2.69), planning (aPR: 2.33; 95% CI 1.99–2.79), attempts (aPR: 3.21; 95% CI 2.56–4.02), and feeling sad or hopeless (aPR: 1.59; 95% CI 1.37–1.84). Students who reported current POM also were significantly more likely than youth who reported past POM to report that they had seriously considered attempting suicide, made a suicide plan, and attempted suicide.CONCLUSIONS:Although POM, particularly current POM, is associated with increases in the risk for suicide-related behaviors and experiences of youth, comprehensive prevention approaches that address the intersections between suicide and POM provide a promising path forward for addressing these public health challenges among youth.
Ceftazidime/avibactam and eravacycline susceptibility of carbapenem-resistant Klebsiella pneumoniae in two Greek tertiary teaching hospitals
Authors: Chatzidimitriou Maria , Chatzivasileiou Panagiota , Sakellariou Georgios , Kyriazidi MariaAnna , Kavvada Asimoula , Chatzidimitriou Dimitris , Chatzopoulou Fani , Meletis Georgios , Mavridou Maria , Rousis Dimitris , Katsifa Eleni , Vagdatli Eleni , Mitka Stella , Theodoros Lialiaris 
Published: March 2021

AbstractThe present study evaluated the carbapenem resistance mechanisms of Klebsiella pneumoniae strains isolated in two Greek tertiary teaching hospitals and their susceptibility to currently used and novel antimicrobial agents.Forty-seven carbapenem resistant K. pneumoniae strains were collected in G. Papanikolaou and Ippokrateio hospital of Thessaloniki between 2016 and 2018. Strain identification and antimicrobial susceptibility was conducted by Vitek 2 system (Biomérieux France). Susceptibility against new antimicrobial agents was examined by disk diffusion method. Polymerase chain reaction (PCR) was used to detect blaKPC, blaVIM, blaNDM and blaOXA-48 genes.The meropenem–EDTA and meropenem–boronic acid synergy test performed on the 24 K. pneumoniae strains demonstrated that 8 (33.3%) yielded positive for metallo-beta-lactamases (MBL) and 16 (66.6%) for K. pneumonia carbapenemases (KPC) production. Colistin demonstrated the highest in vitro activity (87.7%) among the 47 K. pneumoniae strains followed by gentamicin (76.5%) and tigecycline (51%). Among new antibiotics ceftazidime/avibactam showed the highest sensitivity (76.6%) in all strains followed by eravacycline (66.6%). The blaKPC gene was present in 30 strains (63.8%), the blaNDM in 11 (23.4%) and the blaVIM in 6 (12.8%). The blaOXA-48 gene was not detected.Well established antimicrobial agents such as colistin, gentamicin and tigecycline and novel antibiotics like ceftazidime/avibactam and eravacycline can be reliable options for the treatment of invasive infections caused by carbapenem-resistant K. pneumoniae.
Interactions between immune system and the microbiome of skin, blood and gut in pathogenesis of rosacea
Authors: Joura Marie Isolde , Brunner Alexandra , Nemes-Nikodém Éva , Sárdy Miklós , Ostorházi Eszter 
Published: March 2021

AbstractThe increasingly wide use of next-generation sequencing technologies has revolutionised our knowledge of microbial environments associated with human skin, gastrointestinal tract and blood. The collective set of microorganisms influences metabolic processes, affects immune responses, and so directly or indirectly modulates disease. Rosacea is a skin condition of abnormal inflammation and vascular dysfunction, and its progression is affected by Demodex mites on the skin surface. When looking into the effects influencing development of rosacea, it is not only the skin microbiome change that needs to be considered. Changes in the intestinal microbiome and their circulating metabolites, as well as changes in the blood microbiome also affect the progression of rosacea. Recent research has confirmed the increased presence of bacterial genera like Acidaminococcus and Megasphera in the intestinal microbiome and Rheinheimera and Sphingobium in the blood microbiome of rosacea patients. In this review we discuss our current knowledge of the interactions between the immune system and the skin, gut and blood microbiome, with particular attention to rosacea diagnostic opportunities.
Gateway placement and traffic load simulation in sensor networks
Authors: Hajdu László , Dávid Balázs , Krész Miklós 
Published: March 2021

AbstractBecause of the wide variety of possible application fields and the spread of smart devices, the research of wireless sensor networks has become an increasingly important area in the last decade. During the design of these networks, several important aspects have to be considered, for example the lifetime of the network, expected battery usage, or robustness of the installed system. In this paper a simulation environment is introduced that enables the testing of different information spreading methods on the network and provides suggestions for gateway placements with different objectives.
MEDIASI KONSEP DIRI AKADEMIK DALAM PERAN REGULASI DIRI BELAJAR TERHADAP KOMITMEN KEPADA PILIHAN KARIR SISWA SMA
Authors: Mardhiyah Kuny Z , Indianti Wahyu 
Published: March 2021

AbstractThis study aimed to determine the role of academic self-concept in mediating the relationship between self-regulation learning and commitment to career choice in high school students. This research focuses on the dimensions of vocational exploration and commitment, namely openness to explore career choices before committing to a particular career choice. This research uses quantitative approach with 315 students of high school students of X-XI class. Measurement of commitment to career choice is done by measuring tool Commitment to Career Choices Scale sub scale vocational exploraton and commitment. Measurement of self-regulation in learning using Motivated Strategies and Learning Questionnaire, while the academic self-concept was measured using the Academic Self Concept for Adolescents Scale. The result shows that self regulation in learning affects commitment to career choice through academic self concept. The self-regulated skills in applied learning consistently will shape the positive academic self-concept and impact on the increased commitment to career choice among high school students.AbstrakPenelitian ini bertujuan untuk mengetahui peran konsep diri akademik dalam memediasi hubungan antara regulasi diri dalam belajar dan komitmen terhadap pilihan karier pada siswa SMA. Penelitian ini memfokuskan pada salah satu dimensi dari komitmen terhadap pilihan karier, yaitu dimensi vocational exploration and commitment (VEC). Penelitian ini meng­gunakan pendekatan kuantitatif dengan partisipan penelitian berjumlah 315 orang siswa SMA kelas X-XI. Pengukuran komitmen terhadap pilihan karier dilakukan dengan alat ukur Commitment to Career Choices Scale sub skala vocational exploration and commitment. Pengukuran regulasi diri dalam belajar menggunakan Motivated Strategies and Learning Questionnaire, sedangkan konsep diri akademik diukur dengan menggunakan Academic Self Concept for Adolescents Scale. Hasil penelitian menunjukkan bahwa regulasi diri dalam belajar memengaruhi komitmen terhadap pilihan karier melalui konsep diri akademik. Keterampilan regulasi diri dalam belajar yang diterapkan dengan konsisten akan membentuk konsep diri akademik yang positif dan berdampak pada meningkatnya komitmen terhadap pilihan karier dimensi vocational exploration and commitment pada siswa SMA.
PENGUATAN ORIENTASI KARIR BIDANG OTOMOTIF ANAK DIDIK LEMBAGA PEMBINAAN KHUSUS ANAK
Authors: Wulandari Anastasia , Maslihah Sri , Setiadi Asep 
Published: March 2021

This service program is one of life skills education for LPKA students which is expected to be their provision for a career and build economic independence while living a free period and returning to the community (rer-entry). Life skills education provided in the form of vocational training in the field of automotive motorbikes with the aim to improve the career orientation of students of the Special Child Development Institute (LPKA). To test the effect of automotive training on the career orientation of LPKA students, an evaluation of the results of training for LPKA students using the design of one group pretest posttest to 29 LPKA students who will undergo a free period. The evaluation results show the career orientation of LPKA students can be developed through the provision of vocational training in the automotive field, namely the provision of knowledge and skills in pioneering motorcycle entrepreneurship. For future programs, especially related to the provision of vocational training, it is expected to increase the types of skills provided to facilitate the interests of different LPKA students.
Contemporary Outpatient Arthroplasty Is Safe Compared with Inpatient Surgery
Authors: Lan Roy H. , Samuel Linsen T. , Grits Daniel , Kamath Atul F. 
Published: March 2021

Background:
Outpatient joint arthroplasty is a potential modality for increased case throughput and is rising in demand. However, we are aware of no study that has compared outcomes between risk-matched outpatient and inpatient procedures within the last 7 years. The aims of this study were to compare matched patient cohorts who underwent outpatient or inpatient joint arthroplasty in terms of 30-day adverse events and readmission rates.

Methods:
From the National Surgical Quality Improvement Program database, we identified patients who underwent primary total hip arthroplasty (THA), primary total knee arthroplasty (TKA), and primary unicompartmental knee arthroplasty (UKA) from 2009 to 2018. Using 10 perioperative variables, patients who underwent an outpatient procedure were 1:4 propensity score-matched with patients who underwent an inpatient procedure. The rates of 30-day adverse events and readmission were compared using the McNemar test. The risk factors for adverse events and readmissions were identified using multivariate regression.

Results:
Of 574,375 patients identified, 21,506 (3.74%) underwent an outpatient procedure. After propensity score matching, an outpatient joint arthroplasty was associated with a lower rate of adverse events (3.18% compared with 7.45%; p < 0.001). When assessed individually, outpatient TKA (3.15% compared with 8.11%; p < 0.001), THA (4.94% compared with 10.05%; p < 0.001), and UKA (1.78% compared with 3.39%; p < 0.001) were all associated with fewer adverse events overall and there was no difference in the rate of 30-day readmission, when compared with inpatient analogs. Outpatient joint arthroplasty was an independent factor for lower adverse events (odds ratio [OR], 0.407 [95% confidence interval (CI), 0.369 to 0.449]; p < 0.001), with no increase in the risk of readmission (OR, 1.004 [95% CI, 0.878 to 1.148]; p = 0.951).

Conclusions:
Contemporary outpatient joint arthroplasty demonstrated lower rates of adverse events with no increased rate of 30-day readmission when compared with risk-matched inpatient counterparts. Although multiple factors should guide the decision for the site of care, outpatient arthroplasty may be a safe alternative to inpatient arthroplasty.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
A Comparison Between the Theoretical Cross Section Based on the Partial Level Density Formulae Calculated by the Exciton Model with the Experimental Data for (_79^197)Au nucleus
Authors: Abdullah Athraa , Salloum Ali D 
Published: March 2021

In this paper, the theoretical cross section in pre-equilibrium nuclear reaction has been studied for the reaction at energy 22.4 MeV. Ericson’s formula of partial level density PLD and their corrections (William’s correction and spin correction) have been substituted in the theoretical cross section and compared with the experimental data for nucleus. It has been found that the theoretical cross section with one-component PLD from Ericson’s formula when doesn’t agree with the experimental value and when . There is little agreement only at the high value of energy range with the experimental cross section. The theoretical cross section that depends on the one-component William's formula and on-component corrected to spin PLD formula doesn't agree with the experimental cross section. But in case of theoretical cross section based on two-component Ericson's and William's PLD formulae it has been found that there is acceptable agreement when the exciton number is taken .
­­­­Accumulation and clearance of tissue residues and health status of Nile tilapia Oreochromis niloticus (L.) juveniles as influenced by the extended oral oxytetracycline-dosing
Authors: Abraham Thangapalam Jawahar , Roy Anwesha , Julinta Roy Beryl , Singha Jasmine , Patil Prasanna Kumar , Krishna Edapparambil Krishnappan Nanitha , Rajisha Ravindran , Kumar Kesavan Ashok 
Published: March 2021

Abstract
Antibiotics are considered an important primary therapy for bacterial diseases in aquaculture. This study evaluated the influence of oral administration of oxytetracycline (OTC) on feed intake, growth, mortality, residue accumulation and clearance, and histopathological changes in the vital organs of six groups of Nile tilapia Oreochromis niloticus when fed at 0-10 times the therapeutic dose (1X: 80 mg/kg biomass/day) for 10 and 20 consecutive days. The feed intake was reduced only slightly, viz., 2% in 10 days and 4.25% in 20 days dosing trials at 1X-dose compared to control. While in other groups, an OTC-dose-dependent reduction in feed intake up to 31.25% was noted. The fish of 0.5X and 1X groups recorded significantly high biomass; while the other OTC-dosed groups recorded significantly lower biomass than the control. The fold change in biomass between the control and 1X groups was insignificant. A dose-dependent mortalities were recorded in OTC-dosed fish in 10 days (1.67±2.89-6.67±2.89%) and 20 days (3.33±2.89-8.33±2.89%) trials. The OTC concentration in fish muscle established a dose- and time-response relationship. The OTC residue levels in muscle even on day 20 OTC-dosing were lower than the maximum residue limit permitted by Codex Alimentarius (200 ng/g). On day 23 post-OTC-dosing, the residue levels were traces to <10 µg/g in all groups, except the 10X group. The OTC-dosing caused mild to moderate pathological changes in the gills, liver and kidney of O. niloticus and the fish were able to mount adaptive biological responses to overcome the stress with time.
Quantitative trait locus analysis of cucumber fruit texture using double-digest restriction-site-associated DNA sequencing
Authors: Shimomura Koichiro , Sugiyama Mitsuhiro , Kawazu Yoichi , Yoshioka Yosuke 
Published: March 2021

Abstract
Fruit firmness and crispness are important traits of cucumber because they directly affect its commercial value. We performed quantitative trait locus (QTL) analysis of these fruit texture traits with the double-digest restriction-site-associated DNA sequencing (ddRAD-Seq) technique and detected 31 QTLs for fruit firmness: 11 for placenta firmness, 12 for skin firmness, and 8 for flesh firmness; and 25 QTLs for crispness-related scores: 10 for flesh crispness index, 8 for flesh apparent fractal dimension by Richardson plot, and 7 for flesh apparent fractal dimension by box-counting (Kolmogorov’s dimension). Several QTLs associated with flesh firmness and crispness are located near regions for fruit length, diameter, and length-to-diameter ratio, and for resistance to powdery mildew and downy mildew, indicating that gene linkage is likely to limit breeding efficiency. Our results will contribute to the development of informative DNA markers closely linked to genes for desirable fruit texture traits that are required for effective selection of new cultivars.
Identification of Fractional Order System with Scarce Measurement Data Based on Multi Innovation Estimation Algorithm
Authors: Hongwei WANG , Qian ZHANG , Qin ZHA , Ahemaide Mutalifu 
Published: March 2021

Abstract
Aiming at the modeling issues of fractional order Hammerstein system with scarce measurements, a novel multi-innovation hybrid identification algorithm is proposed to deal with them. Firstly, a multi-innovation estimation algorithm based on auxiliary model is presented to estimate the parameters of the nonlinear fractional order system, and a multi-innovation Levenberg-Marquardt algorithm are derived to confirm the fractional orders. Secondly, the convergence properties of the proposed algorithm are analyzed using the lemmas and theorems. Finally, in order to illustrate the effectiveness of the proposed algorithm, two fractional order nonlinear systems with scarce measurements are studied to prove the validity.