bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis and performance of mullite/Y2Si2O7/ZrO2 coating: Microstructure, phase evolution, and thermal shock behavior
Authors: Chen Yongqiang , Chen Mao , Tang Beibei , Liu Guoqi , Li Hongxia , Wang Hailong , Fan Bingbing 
Published: December 2024

AbstractA uniform, dense, and well‐bonded mullite/Y2Si2O7/ZrO2(MYZ) composite barrier coating was synthesized using a spraying technique followed by a two‐step sintering process. The microstructure, phase composition, and thermal shock resistance of the MYZ coating were systematically investigated. The sintering process comprised two stages. In the initial stage (25–1350°C), granular mullite grains transformed into columnar crystals with progressive growth. Concurrently, a eutectic composite of mullite and Y2Si2O7 formed and dispersed within the grain boundaries, significantly enhancing the coating's density and adhesion. In the subsequent stage (∼1400°C), ZrO2 reacted with the eutectic composite to produce yttria‐stabilized zirconia (YSZ) in situ. The YSZ phase exhibited excellent interfacial compatibility with the substrate, markedly improving the coating's high‐temperature stability. As a result, the coating achieved high hardness and a coefficient of thermal expansion matching that of the SiC substrate. Remarkably, the MYZ coating withstood 20 thermal cycles between 25°C and 1200°C without noticeable interfacial damage.
Exploring the Bright and Dark Sides of Social Media Use on Academic Performance: Contrasting Effects on Actual vs. Perceived Performance
Authors: Chao Miao , Sun Weiyi , Liu Jie , Ding Jiahui , Zhu Ye 
Published: December 2024

ABSTRACTBackgroundThe use of social media among students has become debatable concern due to both positive and negative effects on academic performance. Yet, understanding of the diverse patterns of social media use and their influence on actual and perceived academic performance remains limited.ObjectivesThis study distinguishes between academic and excessive social media usage that predicts academic performance while considering academic motivation as a predictive antecedent variable.MethodsA sample of 887 high school students participated in this study through an online questionnaire. The research model was evaluated using the structural equation modelling approach.Results and ConclusionsThe results revealed that academic motivation prompts academic social media usage and reduces excessive use. Additionally, academic usage positively impacts perceived academic performance but has no impact on actual performance. Paradoxically, although excessive use doesn't affect perceived academic performance, there is an observed negative impact on actual academic performance. These findings provide valuable insights for students and educators, illuminating the limitations of academic social media usage and highlighting the detrimental effects of excessive social media use.
TaDL interacts with TaB3 and TaNF‐YB1 to synergistically regulate the starch synthesis and grain quality in bread wheat
Authors: Liu Guoyu , Zhang Runqi , Wu Ziyan , Yu Jiazheng , Lou Hongyao , Zhu Jun , Liu Jie , Gou Jinying , Ni Zhongfu , Sun Qixin , Liang Rongqi 
Published: December 2024

ABSTRACTStarch biosynthesis is a critical factor in wheat (Triticum aestivum L.) quality and yield. However, the full scope of its regulation is not fully understood. Here we report that TaDL interacts with TaB3 and TaNF‐YB1 to synergistically regulate starch biosynthesis and quality in wheat. Genome‐edited tadl mutant lines had smaller and lighter grains with lower total starch and amylose contents compared to wild type (WT). Correspondingly, the transcript levels of starch biosynthesis‐related genes, including TaSUS1, TaSUS2, TaAGPL2, TaSBEIIa, TaGBSSII, and TaSWEET2a, were markedly lower at 15 d after flowering (DAF) in tadl mutants. TaDL physically interacted with TaB3 and TaNF‐YB1 and activated the transcription of TaSUS2 and TaAGPL2 through direct binding to their promoter regions. A null mutant of TaB3 also affected grain filling, with phenotypes similar to those of tadl mutants, whereas overexpression of TaNF‐YB1 promoted grain filling. Our study demonstrated that TaDL plays an essential role in starch biosynthesis and identified an elite allele (TaDL‐BI) associated with starch content, providing insights into the underlying molecular mechanism of wheat grain filling, which may be useful in breeding of high‐yielding wheat and quality improvement.
Global Comparison of Codes of Ethics for Nurses: A Mixed‐Method Collective Case Study Differentiating Aspirational and Mandatory Ethics
Authors: Kim Min Ji , Choi Jiyeon 
Published: December 2024

ABSTRACTAimsTo identify the characteristics and compare the codes of ethics enacted by the Korean Nursing Association and International Council of Nurses.DesignA mixed‐method collective case study.MethodsThis study adopted interpretive approaches comprising case definition and selection, data collection, analysis and interpretation. Based on the developed aspirational versus mandatory ethics analytic framework, we differentiated the aspirational and mandatory codes of the Korean Nursing Association and International Council of Nurses.ResultsThe Korean Nursing Association placed greater emphasis on aspirational ethics (73.3%) than the International Council of Nurses (53.6%). The Korean Nursing Association addressed legal implications regarding adequate services and patient safety, whereas the International Council of Nurses emphasised informed consent and authorised practice. Compared to the Korean Nursing Association's code, the International Council of Nurses' code had one additional chapter and 67 more units. The additional chapter focused on global health.ConclusionSome implications can be considered for future revisions of the code of ethics for Korean nurses. Informed consent needs to be addressed as a legal implication for respecting the patient's right to self‐determination. Furthermore, nurses' attention to global health could be discussed in the context of globalisation.Implications for the ProfessionThe findings of the analysis of the current codes of ethics of national and international nursing organisations may provide scientific evidence for future revisions. An evidence‐based revision of ethical guidelines, as proposed by the findings, underscores the importance of fostering a moral identity consistent with established professional norms and values for nursing.Reporting MethodWe adhered to the Standards for Reporting Qualitative Research.No Patient or Public ContributionGiven that this study is based on the literature, namely the codes of ethics, there is no direct/indirect involvement of patients or the public.
Clinical characterization of a novel episodic ataxia in young working Cocker Spaniels
Authors: Sarró Clara , Stalin Catherine , Gutierrez‐Quintana Rodrigo , Cloquell Ana 
Published: December 2024

AbstractBackgroundEpisodic ataxias (EAs) are a rare group of paroxysmal movement disorders (PMD) described in human medicine with only one suspected case described in veterinary literature.Hypothesis/ObjectivesThis study aimed to provide clinical description of a suspected primary EA in working Cocker Spaniel (WCS) dogs.AnimalsSeven WCS dogs with suspected primary EA.MethodsDescriptive, retrospecitve, multicenter study. Clinical signs, video footage, investigations, treatment, and outcome were reviewed. Owners of affected dogs were invited to complete a questionnaire.ResultsThe mean age at clinical onset was 4 months. Signs were acute and included episodic body swaying, titubation, cerebellar ataxia, wide‐base stance, and hypermetria, all while mentation remained unaltered. Neither autonomic nor vestibular signs nor hyperkinetic movements were observed. Duration of episodes ranged from 30 minutes up to 24 hours, and their frequency varied from weekly to once every 5 months. When investigations were performed, results revealed no abnormalities except for 1 dog that had increased gluten antibody titers. None of the dogs deteriorated, and in dogs with available follow‐up (5/7) the frequency of episodes decreased or completely resolved, from which the majority (4/5) received gluten‐free diet.Conclusion and Clinical ImportanceA novel PMD was identified in young WCS, manifesting as EA. The condition is suspected to have a primary (genetic) etiology, although the cause of this manifestation has not yet been identified. Episodic ataxia in our WCS had a good prognosis. Veterinarians must be aware of this presentation, and further investigations are needed to determine the origin of the clinical signs.
The relationship between radiographic disc calcification score and FGF4L2 genotype in dachshunds
Authors: Sullivan Stacey , Redden David , Hardeng Froydis , Sundqvist Malin , Kutzler Michelle 
Published: December 2024

AbstractBackgroundThe relationship between radiographic disc calcification score and FGF4L2 genotype has been reported in only a small number of dachshunds.HypothesisA genotype with either 0 or 1 FGF4L2 copy will be associated with a lower number of calcified discs (lower K‐n) compared with a genotype with 2 FGF4L2 copies.AnimalsDachshunds registered with the Norwegian or Finnish Kennel Clubs for which both K‐n and FGF4L2 genotype are known (n = 407).MethodsRetrospective study (2012‐2024). The frequency and percentage of dachshunds within each K‐n group (K0, K1/2, K3/4, K5+) by FGF4L2 genotype (FGF4L2/FGF4L2, N/FGF4L2, N/N) were reported. The K‐n distribution differences among genotypes were analyzed by the Cochran‐Mantel‐Haenszel test in SAS 9.4. Significance was defined as P < .05.ResultsA difference in K‐n distribution was found between dachshunds that have 0 or 2 FGF4L2 copies. However, no difference was found in the K‐n distribution between dachshunds that have 1 or 2 FGF4L2 copies.Conclusions and Clinical ImportanceMost dachshunds with 1 FGF4L2 copy have radiographic disc calcification scores that are associated with substantially lower risk of symptomatic disc disease. Radiographic disc calcification scores are similar in dachshunds with 0 and 1 FGF4L2 copies. Given the high allele frequency of FGF4L2, breeding to produce progeny with 1 FGF4L2 copy is expected to be a more achievable short‐term goal for dachshund spinal health breeding programs than breeding for 0 copies. It is recommended that both K‐n and FGF4L2 genotype status be considered when choosing dachshund breeding stock.
Employment and Distributional Effects of Greece's National Minimum Wage
Authors: Roupakias Stelios 
Published: December 2024

ABSTRACTThis paper explores the short‐run effects of minimum wage policies on the distribution of earnings and employment. We exploit the variation in the “bite” of the minimum wage across region‐industry cells, employing data from the Greek Labour Force Survey over the period 2015–2020. Using a Difference‐in‐Differences strategy, we estimate unconditional quantile regressions that yield economically important effects, at the bottom end of the earnings distribution. In particular, the estimated coefficients suggest a 14% and 7% rise in the wages for workers concentrated around the 10th and the 20th percentile, respectively. Importantly, we find that this does not come at the expense of disemployment effects, either at the extensive or at the intensive margin.
ProFESS: Changing the Way Multidisciplinary Student's Professional Behaviour Lapses Are Identified and Managed. An Evaluation of Educators' Perspectives
Authors: Clearihan Lyn , Baird Marilyn , Hodgson Wayne , Dart Janeane , Barber Charlotte , Palermo Claire 
Published: December 2024

ABSTRACTBackgroundBest practice evidence for identifying and managing professional behaviour lapses in a multidisciplinary context is lacking. This study aimed to evaluate multidisciplinary educators' attitudes and perceptions of the ProFESS (Professional standards, Ethical Behaviour and Student Support) framework and its companion Fitness for Practice model, designed and implemented at a large Australian university to address this using a behaviour change approach.MethodsA 72‐item survey based on the Context, Input, Process, Product evaluation framework was completed by 92 multidisciplinary faculty educators and analysed using descriptive and inferential statistics. Content analysis of open text responses occurred.FindingsProFESS and Fitness for Practice were found to be acceptable irrespective of the discipline using them, providing a supportive, transparent, consistent approach for identifying and managing a professional behaviour lapse. Other key strengths of the framework included its student‐centredness and fostering a sense of safety for respondents with potential to improve student‐educator relationships.DiscussionOur findings suggest that ProFESS enhances educators' confidence in managing professional behaviour lapses and that its structural flexibility and adaptability underpin its acceptability for multidisciplinary educators. Many of its positive attributes address the failure to fail barriers. The ProFESS method provides opportunities for greater consistency of application as it does not require individual interpretation of behaviour but does require education and training to apply consistently.ConclusionsThe acceptability of the ProFESS/FfP framework in a multidisciplinary healthcare education context is promising for integrating support and standards, fostering a safety culture for educators and reducing ‘failure to fail’ barriers.
How do we engage with the lesbian, gay, bisexual, and transgender community in blood donation and research? Reflections from the Assessing Donor Variability and New Concepts in Eligibility study
Authors: Crowder Lauren A. , Reik Rita , Stramer Susan L. , Whitaker Barbee I. , Buccheri Renata , Zurita Karla G. , Gehrig Nick , Forbes Susan , Wilson Rodney , Pandey Suchitra , Custer Brian 
Published: December 2024

AbstractBackgroundThe Assessing Donor Variability and New Concepts in Eligibility (ADVANCE) study was a multicenter cross‐organizational collaboration to collect data to inform possible changes in blood donor selection criteria for men who have sex with men. Multiple recruitment approaches were used, and these may be applicable to current efforts in LGBTQ+ community engagement to recruit new blood donors.MethodsFieldwork for ADVANCE was a partnership between blood collection organizations (BCOs) and LGBTQ+ community organizations. First, we had to establish relationships with these organizations based on trust and commitment to common objectives. We developed recruitment materials for online and printed distribution. We worked directly with organizations in each community to tailor outreach. Approaches changed over the course of the COVID‐19 pandemic.ResultsThe study website was a portal for general information about donation policy, the study itself, scheduling study visits, and news stories. It was important to evolve outreach messages and approaches over time. Study team members created changing content and posting schedules on the website and social media platforms. We also worked with community and social media influencers to raise community awareness about the study. Later in the pandemic, we were able to recruit at in‐person community events. These in‐person events were our most successful outreach.DiscussionThe partnerships with LGBTQ+ community organizations, diversity promotion groups, and other members of the community were instrumental in making ADVANCE a success. The approaches we used for the study may be valuable for BCO outreach to attract new blood donors.
RHCE genotyping using next generation sequencing: Allele specific reference sequences
Authors: Tounsi Wajnat A. , Halawani Amr J. , Sillence Kelly A. , Kiernan Michele , Avent Neil D. , Madgett Tracey E. 
Published: December 2024

AbstractBackgroundThe Rh blood group system (ISBT004) is encoded by two homologous genes, RHD and RHCE. Polymorphism in these two genes gives rise to 56 antigens, which are highly immunogenic and clinically significant. This study extended previous work on the establishment of RHD allele specific reference sequences using next generation sequencing (NGS) with the Ion Personal Genome Machine (Ion PGM) to sequence the complete RHCE gene.Study Design and MethodsGenomic DNA (gDNA) samples (n = 87) from blood donors of different serologically predicted genotypes including R1R1 (DCe/DCe), R2R2 (DcE/DcE), R1R2 (DCe/DcE), R2RZ (DcE/DCE), R1r (DCe/dce), R2r (DcE/dce), R0r (Dce/dce), rr (dce/dce), r'r (dCe/dce), and r″r (dcE/dce) were used in this study. The RHCE gene was amplified through overlapping long range‐polymerase chain reaction (LR‐PCR) amplicons and then sequenced with the Ion PGM. Data were analyzed against the human genome reference sequence build hg38 and variants were called.ResultsReferen variant allel VS. In addition to the RHCE reference alleles, different exonic single nucleotide variants (SNVs) were detected that encode known RHCE variant alleles including RHCE*Ce.09, RHCE*ceAR, and RHCE*ceVS.03. Numerous intronic SNVs were detected and compared from samples with different Rh genotypes, to determine their link to a specific Rh haplotype. Based on the exonic and intronic changes detected in different RHCE alleles, three RHCE reference sequences were established and submitted to Genbank (one for the RHCE*Ce allele, one for the RHCE*cE allele, and one for the RHCE*ce allele).ConclusionIntronic SNVs may represent a novel alternative diagnostic approach to investigate known and novel variants of the RH genes and the prediction of Rh haplotype.
Classification of hyperbolic Dehn fillings I
Authors: Jeon BoGwang 
Published: December 2024

AbstractLet be a 2‐cusped hyperbolic 3‐manifold. By the work of Thurston, the product of the derivatives of the holonomies of core geodesics of each Dehn filling of is an invariant of it. In this paper, we classify Dehn fillings of with sufficiently large coefficients using this invariant. Further, for any given two Dehn fillings of (with sufficiently larger coefficients), if their aforementioned invariants are the same, it is shown their complex volumes are the same as well.
Exploratory Study of Psychophysiological Stress in Esports: Training and Competition in Professional League of Legends
Authors: Leis Oliver , Praisan Gantima , Pedraza-Ramirez Ismael , Sharpe Benjamin T. , Laborde Sylvain , Lautenbach Franziska 
Published: December 2024

One goal of sport psychology research is to assist athletes in adapting their training and competitive behavior to maintain or enhance high-level performance under stressful and competitive conditions. To extend this research into esports, a comprehensive understanding of the stress–performance relationship in esports is essential. This knowledge can subsequently guide future intervention studies focused on enhancing players’ performance. This study aimed to explore the relationship between playing esports in competitive settings, and psychological and physiological stress among professional League of Legends players. Unlike previous research focusing on noncompetitive gameplay, we examined seven male professionals during training and competition, measuring perceived motivation and match importance, as well as perceived stress, affect, emotion, heart rate, heart rate variability, and respiratory rate. Data were collected before, during, and after gameplay, evaluating in-game performance (i.e., kill-death-assist ratio, gold, and self-rated performance). Significant differences were observed, with motivation and perceived match importance being greater during competition compared with training. Our findings substantiate that both psychological and physiological stress responses intensify during competitive gameplay in contrast to training. This supports existing theoretical and empirical research, emphasizing the intricate nature of the stress–performance relationship. Practical and theoretical applications are discussed.
Immunometabolic reprogramming in macrophages infected with active and dormant
Cryptococcus neoformans
: differential modulation of respiration, glycolysis, and fatty acid utilization
Authors: Marina Clara Luna , de Castro Raffael J. Araújo , Bellozi Paula , Cruz Ana M. , Bürgel Pedro Henrique , Potter Paul G. Weightman , Beall Craig , Tavares Aldo Henrique , De Bem Andreza , Alanio Alexandre , Coelho Carolina , Bocca Anamélia Lorenzetti 
Published: December 2024

ABSTRACT

Dormancy is an adaptation in which cells reduce their metabolism, transcription, and translation to stay alive under stressful conditions, preserving the capacity to reactivate once the environment reverts to favorable conditions. Dormancy and reactivation of
Cryptococcus neoformans
(
Cn
) are closely linked to intracellular residency within macrophages. Our previous work showed that
in vitro
murine macrophages rely on the viable but not cultivable (VBNC—a dormancy phenotype) fungus from active
Cn
, with striking differences in immunometabolic gene expression. Here, we analyzed the influence of VBNC and active
Cn
on the immunometabolism of infected macrophages, combining metabolic gene expression, mitochondrial membrane potential (ΔΨm), oxygen consumption analysis, and uptake of glucose and fatty acids. The active fungus induced mitochondrial depolarization, and increased glycolysis and mitochondrial oxygen consumption. VBNC infection in bone marrow-derived macrophage (BMDM) caused an attenuated modification in mitochondrial metabolism. However, we found differences in BMDM infected with VBNC vs those infected with active fungus, where VBNC induced an increment in fatty acid uptake in M0 and M1 BMDM, measured by incorporation of BODIPY-palmitate, accompanied by an increase in expression of fatty acid transporters
Fabp1
and
Fabp4
. Overall, distinct fatty acid-related responses induced by VBNC and active
Cn
suggest different immunomodulatory reactions, depending on the microbial growth stage. We posit that, for VBNC, some of these macrophage metabolic responses reflect the establishment of prolonged microbial intracellular residency and possibly initial stages of granuloma formation.