bluuebunny/crossref_metadata_2025_split huggingface dataset:
Breastfeeding Self-efficacy and its Relationship with Perceived Stress and
Breastfeeding Performance in Iranian Mothers with Late Preterm Infants:
A Prospective Study
Authors: Kahforoushan Akram , Hasanpour Shirin , Mirghafourvand Mojgan 
Published: November 2021

Background:
Late preterm infants suffer from several problems after birth, and the key
factor in fighting these problems is effective breastfeeding.

Objective:
To determine breastfeeding self-efficacy and its relationship with perceived stress and
assess breastfeeding performance in mothers with late preterm infants

Methods:
In this prospective study, 171 eligible nursing mothers with late preterm infants born in
Alzahra Medical Center of Tabriz, Iran, were selected via convenience sampling. The Breastfeeding
Self-Efficacy Scale-Short Form was employed to measure breastfeeding self-efficacy, and the
14-item Perceived Stress Scale was used to measure the perceived stress 24 hours after giving
birth. When the child was 4 months old, breastfeeding performance was measured by the Standard
Breastfeeding Performance Questionnaire. The data were analyzed by Pearson and Spearman’s correlation
tests, independent t-test, one-way ANOVA, and multiple linear regression analysis.

Results:
The mean (standard deviation) of breastfeeding self-efficacy was 50.0 (7.8) with scores
ranging from 13 to 65, and the mean (standard deviation) of perceived stress was 26.5 (8.8) with
scores ranging from 0 to 56. The median (25-75 percentiles) of breastfeeding performance score
equaled 2.0 (1.0 to 3.0) with scores ranging from 0 to 6. Based on multiple linear regression analysis
and after adjusting the personal-social characteristics, by increasing the score of breastfeeding
self-efficacy, perceived stress was significantly decreased (B=-0.1, 95 %CI=-0.3 to 0.0). However,
there was no statistically significant relationship between breastfeeding self-efficacy and breastfeeding
performance (p = 0.418).

Conclusion:
Due to the possibility of adjusting breastfeeding self-efficacy and its role in mothers’
perceived stress, developing proper strategies seems to be essential for enhancing breastfeeding
self-efficacy.
Emerging Role of Interleukins for the Assessment and Treatment of Liver
Diseases
Authors: Ali Aaliya L. , Nailwal Namrata P. , Doshi Gaurav M. 
Published: November 2021

Background:
The most common liver diseases are fibrosis, alcoholic liver disease, nonalcoholic
fatty disease, viral hepatitis, and hepatocellular carcinoma. These liver diseases account
for approximately 2 million deaths per year worldwide, with cirrhosis accounting for 2.1% of the
worldwide burden. The most widely used liver function tests for diagnosis are alanine transaminase,
aspartate transaminase, serum proteins, serum albumin, and serum globulins, whereas antivirals
and corticosteroids have been proven to be useful for the treatment of liver diseases. A major
disadvantage of these diagnostic measures is the lack of specificity to a particular tissue or cell
type, as these enzymes are common to one or more tissues. The major adverse effect of current
treatment methods is drug resistance. To overcome these issues, interleukins have been investigated.
The balance of these interleukins determines the outcome of an immune response. Interleukins
are considered interesting therapeutic targets for the treatment of liver diseases. In this review, we
summarize the current state of knowledge regarding interleukins in the diagnosis, treatment, and
pathogenesis of different acute and chronic liver diseases

Objective:
To understand the role of interleukins in the assessment and treatment of different types
of liver diseases.

Methods:
A literature search was conducted using PubMed, Science Direct, and NCBI with the following
keywords: Interleukins, Acute Liver Failure, Alcoholic Liver Disease, Non-Alcoholic Fatty
Liver Disease, Liver Fibrosis, Hepatocellular Carcinoma, Inflammation, Liver injury, Hepatoprotective
effect. Clinical trial data on these interleukins have been searched on Clinicaltrials.gov.

Results:
Existing literature and preclinical and clinical trial data demonstrate that interleukins play
a crucial role in the pathogenesis of liver diseases.

Conclusion:
Our findings indicate that IL-1, IL-6, IL-10, IL-17, IL-22, IL-35, and IL-37 are involved
in the progression and control of various liver conditions via the regulation of cell signaling
pathways. However, further investigation on the involvement of these interleukins is necessary for
their use as a targeted therapy in liver diseases.
Fast and Facile Voltammetric Detection of Acetaminophen at Poly (DL-phenylalanine) Modified Dysprosium-Copper Oxide Nanoparticle/Carbon Composite Paste Electrode
Authors: Itagi Shankar A. , Manjunatha Jamballi G. , Charithra Madikeri M. , Mallu Puttaswamappa , Sandeep Shadakshari , Karthik Chimatahalli S. , Tigari Girish , Varun Donnankatte N. 
Published: November 2021

Introduction:The voltammetric sensing of Acetaminophen (AN) using modified Dysprosium Copper Oxide (DyCuO) Nanoparticles (NP) mixed Carbon Paste Electrode (MCPE) was successfully developed.Methods:The modification of bare NPMCPE was achieved by the polymerisation of DL-Phenylalanine (DLPA). The electroanalysis of the AN was achieved by utilizing the Cyclic voltammetry (CV) approaches. The crystallographic nature of the nanoparticle was studiedviaX-ray Powder Diffraction (XRD) technique. The surface morphology and electrochemical feature of the prepared electrode were evaluated by Field Emission Scanning Electron Microscopy (FE-SEM) and Electrochemical Impedance Spectroscopy (EIS) techniques.Results:The modified sensor exhibited an excellent electrocatalytic activity towards the electroanalysis of the AN. Several aspects, such as the number of polymerisation cycles, variation of pH, and the impact of scan rate were investigated in 0.2 M supporting electrolyte (pH 7) at a sweep rate of 0.1 Vs-1. The suggested sensor shows a very low detection limit (11.95×10-8M) with a linear range of 2.0 to 50.0 µM, which exhibits excellent sensitivity.Conclusion:The stable and reusable sensor was applied for the estimation of AN in the tablet sample. Thus, P(DLPA)MNPMCPE was utilized as the most capable sensor for the voltammetric detection of AN.
Aqueous Flare, Functional-Morphological Parameters, and Cytokines in Age-Related Macular Degeneration after Anti-VEGF Treatment
Authors: Motohashi Ryosuke , Noma Hidetaka , Yasuda Kanako , Kasezawa Yuko , Goto Hiroshi , Shimura Masahiko 
Published: November 2021

Purpose:The role of inflammation and cytokines in AMD and anti-Vascular Endothelial Growth Factor (anti-VEGF) treatment remains unclear. Therefore, this study aimed to examine whether anti-VEGF treatment for exudative Age-related Macular Degeneration (AMD) affects aqueous flare value (an indicator of inflammation), functional-morphologic parameters, and aqueous humor levels of cytokines or inflammatory mediators.Methods:We compared aqueous humor levels of 8 cytokines, growth factors (including VEGF), and inflammatory mediators in 43 patients who received anti-VEGF treatment with aflibercept for AMD and 24 healthy controls by the suspension array method. In addition, we measured aqueous flare values with a laser flare meter and Central Macular Thickness (CMT) and Macular Volume (MV) by optical coherence tomography.Results:The patient group had a significantly higher aqueous flare value than the control group. At baseline, CMT showed significant correlations with aqueous humor levels of soluble intercellular adhesion molecule-1 (sICAM-1), monocyte chemoattractant protein 1 (MCP-1), interleukin (IL)-6, and IL-8 and MV, with aqueous humor levels of VEGF, sICAM-1, MCP-1, IL-6, and IL-8. Moreover, we found significant correlations between aqueous flare value and aqueous humor levels of MCP-1, IL-6, IL-8, and interferon-gamma–inducible protein 10. One month after anti-VEGF treatment, the patient group showed a significant correlation between the change in MV and improvement in best-corrected visual acuity (BCVA); CMT showed no such correlation.Conclusion:Inflammation appears to be involved in AMD. Change in MV may be an index of improvement in BCVA in patients receiving anti-VEGF treatment for AMD.
Validation of a Predictive Model of Pre-eclampsia from a Cohort Study in Pregnant Women
Authors: Vadell Haydée C. , Barroso Reinaldo L. , Dieguez Aglae C. , Pujals Adrian M. , Á. Guerra Eloy D. 
Published: November 2021

Background & Aims:
To validate a predictive model of pre-eclampsia for classifying pregnant women into pre-eclamptic and healthy groups.

Materials and Methods:
A cohort study was carried out in a total of 132 pregnant women, including biochemical and clinical parameters for assessing the classification performed by a predictive model of pre-eclampsia from a 10-fold cross-validation method and the experts’ criteria.

Results:
A highly predictive value was obtained from the set of biochemical parameters included in the proposed model. Wilks’ Lambda, eigenvalues, canonical correlation, and distances between centroids of the groups point to the high classificatory power of the discriminant function. Risk indexes, computed from the centroids, provided a measure of different risk levels for this condition. The analysis of these indexes in a prospective study allowed assessing the effect of the parameters. The new ten models obtained from a 10-fold cross-validation achieved a 100% of correct classification (AUC:1.00; CI:0.00-1.00; p=0.00). The sensitivity and specificity of the model, obtained from ROC curves, showed the consistency of the model, even though there were only four clinical manifestations of the entity. Moreover, the risk indexes were assessed from the experts’ criteria in the cohort study, showing an AUC of 100% in the 3rd trimester of pregnancy.

Conclusions:
The model and proposed pre-eclampsia risk indexes could constitute an accurate diagnostic tool, employing markers of oxidative stress as a significant element in the prediction of this entity.
Peningkatan Keterampilan dan Perekonomian Masyarakat Pesisir Pulau Lemukutan melalui Pelatihan Pembuatan Snack Berbasis Rumput laut
Authors: Safitri Ikha , Warsidah  , Sofiana Mega Sari Juane , Yuliono Agus 
Published: November 2021

The waters of Lemukutan Island have the potential of natural resources, including seaweed. Since 2011, Lemukutan Island has been the largest seaweed cultivation center in West Kalimantan. However, the Covid-19 pandemic has attacked all sectors and caused a decline in prices for fishery-based food commodities. This condition causes the farmers to suffer losses and the seaweed cultivation activity also decreases. Training on making snacks and seaweed jelly boba has been carried out to revive the economy of the coastal communities of Lemukutan Island. This activity involves all levels of the community through representatives of each RT using a hybrid method. Training is carried out with strict health protocols. This activity aims to improve the skills of coastal communities in processing seaweed-based foods. The training participants were very enthusiastic, from the presentation about the benefits of consuming seaweed for human health to the practice of making seaweed snacks and jelly.
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Perairan Pulau Lemukutan memiliki potensi sumber daya alam yang melimpah termasuk rumput laut. Sejak 2011, Pulau Lemukutan menjadi sentra usaha budi daya rumput laut terbesar di Kalimantan Barat. Namun, pandemi Covid-19 telah menyerang semua sektor kehidupan dan menyebabkan kemerosotan harga pada komoditas pangan berbasis perikanan. Kondisi ini mengakibatkan pembudi daya mengalami kerugian dan usaha budi daya rumput laut di Pulau Lemukutan juga menurun. Pelatihan pembuatan snack krenyes dan jelly boba rumput laut telah dilaksanakan untuk menumbuhkan kembali perekonomian masyarakat pesisir Pulau Lemukutan. Kegiatan ini melibatkan seluruh lapisan masyarakat Pulau Lemukutan melalui perwakilan tiap RT dengan metode hibrid. Pelatihan dilaksanakan dengan protokol kesehatan yang tegas. Kegiatan ini bertujuan untuk meningkatkan keterampilan masyarakat pesisir dalam mengolah makanan berbasis rumput laut. Peserta pelatihan sangat antusias mengikuti kegiatan, mulai dari pemaparan materi tentang manfaat dari mengonsumsi rumput laut bagi kesehatan manusia hingga praktik pembuatan snack dan jelly rumput laut.
PERILAKU HIGIENE PRIBADI TERHADAP KECACINGAN PADA MURID SDN MUARA PAGATAN UJUNG, KECAMATAN KUSAN HILIR KABUPATEN TANAH BUMBU
Authors: Hairani Budi , Annida Annida , Hariyati Erly , Andiarsa Dicky , Juhairiyah Juhairiyah 
Published: November 2021

Penularan kecacingan pada anak usia sekolah dasar dapat terjadi dikarenakan perilaku higiene pribadi yang kurang baik. Salah satu kunci keberhasilan penanggulangan kecacingan adalah dengan memperbaiki perilaku higiene pribadi pada masyarakat terutama pada kelompok yang paling rentan tertular yaitu anak usia sekolah dasar. Penelitian ini bertujuan untuk mengetahui tingkat prevalensi kecacingan pada murid SDN Muara Pagatan Ujung serta mengidentifikasi faktor perilaku anak dalam menjaga kebersihan pribadi yang diduga berisiko terhadap penularan kecacingan. Penelitian dengan desain potong lintang dilakukan di SDN Muara Pagatan Ujung, Kecamatan Kusan Hilir Kabupaten Tanah Bumbu pada bulan Desember tahun 2016. Sampel merupakan total sampling dari seluruh populasi siswa SDN Muara Pagatan Ujung. Data yang dikumpulkan berupa hasil pemeriksaan feses dan hasil wawancara pada siswa. Diketahui prevalensi kecacingan sebesar 13%. Hasil wawancara beberapa faktor perilaku higiene siswa terhadap kecacingan yang masih cukup tinggi yaitu tidak menggunakan alas kaki setiap keluar rumah (54%), tidak mencuci tangan dan kaki setelah bermain di tanah (47%) dan tidak mencuci tangan pakai sabun sebelum makan (50%). Perlu dilakukan edukasi pada siswa secara intensif mengenai pentingnya menjaga kebersihan pribadi terutama kebiasaan mencuci tangan dan kaki yang diiringi dengan pengadaan fasilitas pendukung kebersihan di sekolah seperti tempat cuci tangan dengan sabun dan adanya peraturan yang mengharuskan siswa untuk selalu memakai alas kaki.
HUBUNGAN SUMBER AIR MINUM DENGAN KEJADIAN DIARE DI PROVINSI SUMATERA SELATAN
Authors: Marini Marini , Ofarimawan Dheli , Ambarita Lasbudi P 
Published: November 2021

Penyakit diare merupakan penyebab utama kedua kematian pada anak di bawah usia lima tahun di dunia dengan angka kematian sekitar 525.000 anak setiap tahunnya. Menurut data Riskesdas 2018 diketahui bahwa prevalensi diare berdasarkan diagnosis tenaga kesehatan adalah sebesar 6,8%. Hal ini menunjukkan kenaikan 2,3% jika dibandingkan dengan hasil Riskesdas 2013 yaitu hanya 4,5%. Prevalensi diare untuk Provinsi Sumatera Selatan pada tahun 2018 sebesar 5,5%. Analisis ini bertujuan untuk melihat hubungan sumber air minum yang digunakan sehari-hari oleh masyarakat dengan angka kejadian diare di Provinsi Sumatera Selatan menggunakan hasil olah data dari Survei Sosial Ekonomi Nasional (Susenas) tahun 2018. Analisis yang digunakan adalah bivariat dengan korelasi pearson. Hasil analisis data menunjukkan adanya hubungan yang sangat erat antara sumber air minum air ledeng dengan kejadian diare dengan nilai R square sebesar 0,712 dan menunjukkan arah hubungan yang positif. Kesimpulan analisis ini menunjukkan bahwa angka kejadian diare berhubungan dengan penggunaan air ledeng sebagai sumber air minum. Promosi kesehatan berupa komunikasi, informasi dan edukasi (KIE) tentang pengelolaan sumber air untuk di konsumsi perlu terus digalangkan dalam upaya meningkatkan derajat kesehatan masyarakat.
GAMBARAN DISTRIBUSI SPESIES Anopheles DAN PERANNYA SEBAGAI VEKTOR MALARIA DI PROVINSI NUSA TENGGARA TIMUR, PAPUA DAN PAPUA BARAT
Authors: Mahdalena Vivin , Wurisastuti Tri 
Published: November 2021

Malaria merupakan penyakit tular nyamuk yang masih menjadi penyebab utama kematian di negara berkembang. Malaria juga masih endemis di sebagian besar wilayah Indonesia, terutama di daerah Indonesia bagian Timur. Tiga provinsi di Indonesia dengan annual parasite incidence (API) tertinggi per 1000 penduduk pada tahun 2018 yaitu Nusa Tenggara Timur (NTT), Papua dan Papua Barat. Pengetahuan dan pemahaman mengenai nyamuk Anopheles sebagai vektor malaria di lokasi penyebarannya sangat penting dalam program intervensi pengendalian vektor malaria yang optimal. Artikel ini merupakan studi literatur dimana informasi diperoleh dari buku, artikel penelitian atau jurnal ilmiah, dan laporan hasil penelitian dari rentang tahun 2003 sampai tahun 2019. Anopheles yang ditemukan di Provinsi NTT, Papua dan Papua Barat yaitu An. vagus, An. barbirostris, An. subpictus, An. sundaicus, An. indefinitus, An. tesselatus, An. maculatus, An. aconitus, An. kochi, An. minimus, An. annularis, An. flavirostris, An. umbrosus, An. annulipes, An. farauti, An. barbumbrosus, An. ludlowae, An. punctulatus, An. aitkenii, An. longirostris, An. peditaeniatus, An. koliensis, An. bancrofti, An. hinesorum, dan An. meraukensis. Anopheles yang sudah terkonfirmasi sebagai vektor malaria yaitu An. barbirostris, An. subpictus, An. sundaicus, An. flavirostris, An. minimus, An. farauti, An. punctulatus dan An. longirostris. Perilaku kesukaan mengisap darah dari beberapa Anopheles yang menjadi vektor malaria lebih cenderung bersifat antropofilik.
Characterization of Cr(III) interaction with kaolinite – Effect of the presence of Cr(VI)
Authors: Bounab Nourhane Amani , Boukhalfa Chahrazed , Reinert Laurence , Duclaux Laurent 
Published: November 2021

Abstract
In the present study, experiments were performed to characterize the effectiveness of kaolinite in Cr(III) removal from water in the absence and in the presence of Cr(VI). The results of batch experiments, show that the efficiency of Cr(III) removal by kaolinite increases with the increase of pH and temperature in both cases. The effect of the presence of Cr(VI) on the adsorption of Cr(III) by kaolinite depends on the solution pH and on the concentrations of the two ions. Whatever the system, the removal kinetic of Cr(III) is well described by the pseudo-second order model. Spectroscopic analyses reveal that Cr(III) interaction with kaolinite is mainly electrostatic.
Effects of antioxidant diet on the RBC indices in fructose-induced obesity rat model
Authors: Bakalov Dimitar , Sabit Zafer , Tafradjiiska Radka , Andreeva-Gateva Pavlina 
Published: November 2021

Abstract
The oxidative stress is one of the known and discussed culprits for development and progression of the disturbances in Metabolic syndrome (MetS). In our study, we are investigating the effects of antioxidant additives as additional treatment and prophylaxis in a model of MetS.
We are using a fructose-induced metabolic syndrome rat model to examine the effects of antioxidant preparation ZellSchutz. Four experimental groups were formed using male Wistar rats (n = 60). The control group received standard rat chow, the other groups received either ZellSchutz (Z), fructose (F), or fructose and ZellSchutz (ZF).
Our results showed an unexpected increase in the RBC indices in rats with dual treatment. There was a significant increase in hemoglobin concentration, MCHC, and MCV in those animals (p<0.001).
The preliminary data shows the important role of antioxidants as supplementary therapy in metabolic syndrome. Further investigations will be carried on to reveal the molecular mechanisms of the observed changes.
Allergenic potential of Platanus L. species in urban environment
Authors: Tsvetanova Rusana 
Published: November 2021

Abstract
The species of the genus Platanus L. are widely used in urban green infrastructure in Bulgaria and abroad, but are proven to be a serious source of allergen pollen emissions. The number of people, affected by pollinosis, is increasing every year and this affects the world economy and health of the population in a high level. The pollen of the plane tree is light, very small and spreads anemophilically. This is one of the genera that produce the largest amount of pollen per inflorescence. This makes Platanus a tree of a high allergy potential that has the tendence to get higher in time, because of its increasing use in urban green spaces. The aim of this study is to collect data for allergy potential of the three species of plane tree in some of the European countries, where the allergy is a significant problem, and to compare the sensitization of patients to its pollen in Bulgaria.
Natural tourist resources in Rhodope tourist region
Authors: Vasileva Vanya , Kabakchieva Dora , Sabrieva Sevdzhan , Vladev Dimitar 
Published: November 2021

Abstract
Rhodope Tourist Region is one of the most attractive tourist regions in Bulgaria and one of the few that stand out with almost uniform year-round development of tourist activities. The outlines of the tourist area largely coincide with the outlines of the mountain of the same name. This fact predetermines the exceptional richness and diversity of natural tourist resources. Here are the largest coniferous forests in the country, some of the largest dams, the largest number of caves used for tourist purposes, many mineral springs, bizarre rock formations, etc. The relatively well-preserved natural environment is a prerequisite for the presence of extremely high biodiversity, as well as a large number of protected areas. The region is specialized in mountain tourism, incl. ski tourism and hiking. In connection with the available natural tourist resources, the tourism product is increasingly enriched with various specialized types of tourism, incl. balneotherapy tourism, ecotourism, rural tourism, etc. In connection with the increasingly intensive tourist load, the problem of protecting the natural tourist resources from the growing anthropogenic pressure, as well as the prospects for sustainable development of the tourist industry in the region are becoming especially relevant. The aim of the present paper is to valorize the natural tourist resources of the Rhodope tourist region and to give guidelines for their sustainable use.
Degrees of Freedom: Is Good Philosophy Bad Science?
Authors: Williamson Timothy 
Published: November 2021

Abstract
The lecture starts by considering analytic philosophy as a tradition, and its global spread over recent years, of which Disputatio’s success is itself evidence. The costs and benefits of the role of English as the international language of analytic philosophy are briefly assessed. The spread of analytic philosophy is welcomed as the best hope for scientific philosophy, in a sense of ‘science’ on which mathematics, history, and philosophy can all count as sciences, though not as natural sciences. Arguably, experimental philosophy provides no plausible alternative methodology for philosophy, only a way of psychologizing it. However, it serves a useful purpose by highlighting the inadequacy of current methods for detecting errors in judgments on possible cases, which may result from reliance on possibly universal but imperfectly reliable cognitive heuristics. The problem is exacerbated by analytic philosophers’ tendency to regard increased flexibility in a theoretical framework as progress, where natural scientists would treat it as methodologically vicious profligacy with degrees of freedom. The result is a familiar type of bad science, overfitting theory to uncritically accepted data. The recent ‘hyperintensional revolution’ may be an example of such overfitting, it is suggested. The lecture ends with a call for a more miserly attitude to degrees of freedom.