bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epicardial Adipose Tissue Volume As a Marker of Subclinical Coronary Atherosclerosis in Rheumatoid Arthritis
Authors: Karpouzas George A. , Rezaeian Panteha , Ormseth Sarah R. , Hollan Ivana , Budoff Matthew J. 
Published: February 2021

ObjectiveTo assess epicardial adipose tissue volume (EATV) and its link to coronary atherosclerosis and plaque morphology in patients with rheumatoid arthritis (RA) and in age‐ and sex‐matched controls.MethodsComputed tomography angiography was used to evaluate EATV and coronary plaque in 139 RA patients and 139 non‐RA controls. All models assessing the effect of EATV on plaque were adjusted for age, sex, hypertension, diabetes, dyslipidemia, smoking status, family history of coronary artery disease, and obesity (body mass index of ≥30 kg/m2). Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated.ResultsMean ± SD log‐transformed EATV was similar in patients with RA (4.69 ± 0.36) and controls (4.70 ± 0.42). EATV was higher in RA patients with atherosclerosis compared to those without atherosclerosis (P = 0.046). In stratified analyses, EATV was associated with the number of segments with plaque in RA patients (rate ratio 1.20 [95% CI 1.01–1.41] per 1‐SD increment of log‐unit increase in EATV) but not in controls (P for interaction = 0.089). Likewise, EATV (per 1‐SD log‐unit increase) was related to the presence of multivessel or obstructive disease (OR 1.63 [95% CI 1.04–2.61]), noncalcified plaque (OR 1.78 [95% CI 1.17–2.70]), and vulnerable plaque (OR 1.77 [95% CI 1.03–3.04]) in RA patients but not in controls (P for interaction ≤ 0.048 for each). Among RA patients, EATV was associated with the number of segments with plaque in those with RA for <10 years who did not develop any cardiovascular risk factors and who were not obese (P for interaction ≤ 0.017).ConclusionDespite similar EATVs in RA patients and controls, EATVs were associated with greater plaque burden and presence of plaques with a noncalcified component and vulnerability features only in RA patients. EAT may be more pathogenic in RA and play a role in early‐stage atherosclerosis. Its value as a biomarker of subclinical atherosclerosis and cardiovascular risk in RA warrants further studies.
Investigation of magneto‐thermal evolution of AXP 1E 2259 + 586
Authors: Wang Hui , Yang Xiao‐Feng , Song Dong‐Ling , Jia Huan‐Yu 
Published: February 2021

AbstractIn this work, we calculated the toroidal magnetic field decay rates and magnetic energy decay rates by considering the general relativity effect of AXP 1E2259 + 586 associated with the supernova remnant CTB 109. The results confirmed that the high thermal radiation on the surface of the star could be attributed to Joule heating caused by the dissipation of crustal magnetic field. We also investigated the effects of ultrastrong magnetic fields on magnetization parameter and thermal conductivity in the crust.
Building Meaning: Meta‐analysis of Component Skills Supporting Reading Comprehension in Children with Autism Spectrum Disorder
Authors: Sorenson Duncan Tamara , Karkada Manasi , Deacon S. Hélène , Smith Isabel M. 
Published: February 2021

The ability to understand what one reads, or reading comprehension, is central to academic success. For many children with autism spectrum disorder (ASD), reading comprehension is a noted area of challenge. For children with typical development, it is well established that successful reading comprehension requires two broad skills: word reading and oral language. For children with ASD, word reading is often believed to be relatively intact, even in the face of poor reading comprehension, suggesting that deficits in oral language, more than in word reading, underlie reading comprehension deficits. Yet, extant research has suggested the importance of both skills. To clarify the role of these skills in the reading comprehension of children with ASD, we conducted a meta‐analysis. ERIC, PsycINFO, PubMed, and Proquest Dissertation & Theses were searched for studies of reading comprehension in children with ASD, published up to May 2019. We identified 26 relevant studies about children with ASD (aged 6–18 years) that included both a measure of word reading and reading comprehension. Hunt‐Schmidt Random Effects Models showed similar mean correlations between reading comprehension and the component skills of word reading (M r = 0.65 [0.27–1.03]) and oral language (M r = 0.61 [0.33–0.88]). These findings demonstrate that these skills are essential for reading comprehension in children with ASD, making contributions of similar size. This study advances our understanding of the mechanisms by which children with ASD understand what they read, providing a foundation on which to build programmatic research into each of these mechanisms.Lay SummaryAcademic progress is closely tied to children's ability to understand what they read. Yet reading comprehension is difficult for many children with autism spectrum disorder (ASD). We used a statistical method to summarize existing research on the skills that children with ASD use to understand what they read. We found that the reading comprehension of children with ASD was related to a similar extent to both their ability to read individual words and their oral language skills. These findings suggest that both areas should be assessed in order to determine appropriate interventions to support reading comprehension for children with ASD. Autism Res 2021, 14: 840–858. © 2021 International Society for Autism Research, Wiley Periodicals LLC.
Relationship between US and Brazilian ethanol prices: new evidence based on fractal regressions
Authors: Quintino Derick David , Cantarinha Ana , Ferreira Paulo Jorge Silveira 
Published: February 2021

AbstractTwo different fractal regression methodologies were employed with the aim of understanding the relationship between prices of ethanol produced in the USA and Brazil, the most important producers of ethanol. These methodologies, which have the advantage of giving us information about the relationships between different timescales, could also provide interesting and important information about this particular market. Our results suggest, first, some differences in the basic price in these markets, and second, a positive relationship between prices (as expected) but not a one‐to‐one relationship. © 2021 Society of Chemical Industry and John Wiley & Sons, Ltd
Hepatocyte nuclear factor 1 beta: A perspective in cancer
Authors: Chandra Shubhra , Srinivasan Srilakshmi , Batra Jyotsna 
Published: February 2021

AbstractHepatocyte nuclear factor 1 beta (HNF1 β/B) exists as a homeobox transcription factor having a vital role in the embryonic development of organs mainly liver, kidney and pancreas. Initially described as a gene causing maturity‐onset diabetes of the young (MODY), HNF1β expression deregulation and single nucleotide polymorphisms in HNF1β have now been associated with several tumours including endometrial, prostate, ovarian, hepatocellular, renal and colorectal cancers. Its function has been studied either as homodimer or heterodimer with HNF1α. In this review, the role of HNF1B in different cancers will be discussed along with the role of its splice variants, and its emerging role as a potential biomarker in cancer.
Female therapists’ experiences of working with male clients who are sexually attracted to them—An exploratory study using a free association narrative interview method
Authors: Lukac‐Greenwood Jasenka , van Rijn Biljana 
Published: February 2021

AbstractSexual attraction between human beings is a pervasive phenomenon, impacting the process of psychotherapy, as well as other areas of social engagement. However, within ethical psychotherapy practice the experience of attraction could not lead to enactment without ethical misconduct or premature therapeutic termination. This qualitative study focused on female therapists' experiences of working with male clients who were sexually attracted to them. It employed Hollway and Jefferson's (2008) hybrid method ‘free association narrative interview’, which involved multiple unstructured interviews with five female participants. The results of the study suggested that participants’ experience differed depending on whether they felt reciprocal sexual attraction. On occasions when therapists were not attracted towards their clients, they struggled with unwanted sexual attraction because they feared having to reject their client and the retaliation this may entail. On such occasions, therapists expressed a sense of vulnerability, discomfort with power inequality and a sense of being at fault. Conversely, when therapists felt sexually attracted to their clients, they managed the dynamic by framing it within a context of loving as opposed to purely erotic feelings. The study suggests that working directly with sexual feelings is a challenge for female therapists, requiring personal development work, supervision and institutional support to address the complex interplay of individual, clinical and societal issues, which appear to play a part in this difficulty.
‘Educate, Empower and Inspire’: An Evaluation of a Preventative Service for Young People at Risk of Sexual Exploitation
Authors: Unwin Peter , Jones Alexandra 
Published: February 2021

Key Practitioner Messages

Young people at risk of child sexual exploitation (CSE) value peer mentoring and will respond to services that they regard as authentic, consistent and tailored to their needs.
Practitioners should always endeavour to prioritise the voices of young people - they are articulate about CSE.
Arts‐based projects should be given fuller consideration as a potentially effective vehicle for building resilience and combatting the CSE threat.
(+/−)‐Alashanoid N, Two Enantiomeric Sesquiterpenes from Syringa pinnatifolia
Authors: Huang Meiwen , Jiao Shungang , Ge Fuxing , Shana Wuken , Li Anni , Zhou Xiaochun , Liu Changxin , Tu Pengfei , Chai Xingyun 
Published: February 2021

AbstractTwo enantiomeric humulane sesquiterpenes, namely (+)‐alashanoid N (1a) and (−)‐alashanoid N (1b), along with two known analogs ((2R,3R,5R)‐2,3‐epoxy‐6,9‐humuladien‐5‐ol‐8‐one (2) and (2R,3S,5R)‐2,3‐epoxy‐6,9‐humuladien‐5‐ol‐8‐one (3)), were described from the peeled stems of a folk Mongolian herbal medicine Syringa pinnatifolia. Their structures were characterized based on UV, IR, NMR, and HR‐ESI‐MS data analyses, and the absolute configurations were determined by data analysis of X‐ray diffraction and quantum chemical calculations. (+/−)‐Alashanoid N showed inhibition against NO production in RAW 264.7 macrophage cells with IC50 values of 90.1 μM and 71.7 μM, and protective effect against oxygen‐glucose deprivation injury to H9c2 cells at a concentration of 20 μM and 5 μM, respectively.
Valve‐in‐valve transcatheter aortic valve replacement versus redo surgical valve replacement for degenerated bioprosthetic aortic valve: An updated meta‐analysis comparing midterm outcomes
Authors: Thandra Abhishek , Abusnina Waiel , Jhand Aravdeep , Shaikh Kashif , Bansal Raahat , Pajjuru Venkata S. , Al‐Abdouh Ahmad , Kanmanthareddy Arun , Alla Venkata M. 
Published: February 2021

AbstractBackgroundRedo surgical aortic valve replacement (redo SAVR) and valve‐in‐valve transcatheter aortic valve replacement (ViV TAVR) are the two treatment strategies available for patients with severe symptomatic bioprosthetic aortic valve dysfunction. Herein, we performed a systematic review and meta‐analysis comparing both early and mid‐term outcomes of ViV TAVR versus redo SAVR in patients with bioprosthetic aortic valve disease.MethodsPubMed, Cochrane reviews, and Google scholar electronic databases were searched and studies comparing ViV TAVR versus redo SAVR were included. The primary outcome of interest was mid‐term (1–5 years) and 1‐year all‐cause mortality. Secondary outcomes included were 30‐day all‐cause mortality, myocardial infarction, pacemaker implantation, stroke, acute kidney injury, major or life‐threatening bleeding, and postprocedural aortic valve gradients. Pooled risk ratios (RR) with their corresponding 95% confidence intervals (CIs) were calculated for all outcomes using the DerSimonian–Laird random‐effects model.ResultsNine observational studies with a total of 2,891 individuals and mean follow‐up of 26 months met the inclusion criteria. There is no significant difference in mid‐term and 1‐year mortality between ViV‐TAVR and redo SAVR groups with RR of 1.15 (95% CI 0.99–1.32; p = .06) and 1.06 (95% CI 0.69–1.61; p = .8). 30‐day mortality rate was significantly lower in ViV‐TAVR group with RR of 0.65 (95% CI 0.45–0.93; p = .02). ViV‐TAVR group had lower 30‐day bleeding, length of stay, and higher postoperative gradients.ConclusionOur study demonstrates a lower 30‐day mortality and similar 1‐year and mid‐term mortality for ViV TAVR compared to redo SAVR despite a higher baseline risk. Given these findings and the ongoing advances in the transcatheter therapeutics, VIV TAVR should be preferred over redo SAVR particularly in those at intermediate‐high surgical risk.
Left atrial appendage occlusion in chicken‐wing anatomies: Imaging assessment, procedural, and clinical outcomes of the “sandwich technique”
Authors: Freixa Xavier , Tzikas Apostolos , Aminian Adel , Flores‐Umanzor Eduardo , De Backer Ole , Korsholm Kasper , Ben Yedder Mohamed , Gonzalez‐Ferreiro Rocío , Agudelo‐Montañez Victor , Gilhofer Thomas , Simon François , Samaras Athanasios , Regueiro Ander , Sondergaard Lars , Cruz‐Gonzalez Ignacio , Arzamendi Dabit , Saw Jacqueline , Ibrahim Reda , Nielsen‐Kudsk Jens Erik 
Published: February 2021

AbstractObjectivesTo describe imaging assessment, procedural and follow‐up outcome of patients undergoing left atrial appendage (LAA) occlusion (LAAO) using a “sandwich” technique.BackgroundThe presence of a LAA with chicken wing morphology constitutes a challenge that sometimes requires specific occlusion strategies like the “sandwich” technique. However, procedural and follow‐up data focusing on this implanting strategy is scarce.MethodsThis multicenter study collected individual data from eight centers between 2012 and 2019. Consecutive patients with chicken‐wing LAAs defined as an early (<20 mm from the ostium) and severe bend (>90°) who underwent LAAO with Amplatzer devices and using the “sandwich” technique were included in the analysis.ResultsOverall, 190 subjects were enrolled in the study. Procedures were done with the Amulet device (85%) and the Amplatzer Cardiac Plug (15%). Successful implantation was achieved in 99.5% with ≤1 partial recapture in 80% of cases. Single (46.2%) and dual antiplatelet therapy (39.4%) were the most used antithrombotic therapies after LAAO. In‐hospital major adverse events rate was 1.5% with no deaths. One patient (0.5%) had cardiac tamponade requiring percutaneous drainage. With a mean follow‐up of 19.6 ± 14.8 months, the mortality and stroke rates were 7.7%/year and 2.5%/year, respectively. Follow‐up transesophageal echocardiography (TEE) at 2–3 months showed device‐related thrombosis in 2.8% and peri‐device leak ≥3 mm in 1.2% of patients.ConclusionsIn a large series of patients with chicken wing LAA anatomies undergoing LAAO, the use of the “sandwich” technique was feasible and safe. Preprocedural imaging was a key‐factor to determine specific measurements.
Patient with Down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial R3 chemotherapy
Authors: Hu Zhongbo , VanHeyst Kristen A. , Dalal Jignesh , Hackney Lisa 
Published: February 2021

AbstractDS‐ALL has a higher rate of relapse and treatment‐related mortality. The newer immunotherapies are potentially better options. Relapsed ALL with positive MRD has a poor prognosis. Transient long‐term remission after ALL relapse due to partial chemotherapy combined severe infection is rare.
The great pretender—Bell’s palsy secondary to SARS‐CoV‐2?
Authors: Neo Wei Li , Ng Jeremy Chung Fai , Iyer N. Gopalakrishna 
Published: February 2021

AbstractThis case series highlights a possible association between isolated facial nerve palsy and SARS‐CoV‐2. Caution should be exercised in the use of steroids in patients with COVID‐19 as its impact is still not well established.
Synthesis and Photophysical Properties of Soluble N‐Doped Rubicenes via Ruthenium‐Catalyzed Transfer Hydrogenative Benzannulation
Authors: Shuler William G. , Parvathaneni Sai P. , Rodriguez Jacob B. , Lewis Taylor N. , Berges Adam J. , Bardeen Christopher J. , Krische Michael J. 
Published: February 2021

AbstractRuthenium‐catalyzed butadiene‐mediated benzannulation enabled the first synthesis of 3,10‐(di‐tert‐butyl)rubicene and its N‐doped derivatives as well as preliminary studies on their photophysical properties. Unlike the parent rubicene and 3,10‐(di‐tert‐butyl)rubicene, which adopt classical herringbone‐type packing motifs in the solid state, the N‐doped congener 7 b displayed columnar packing with an alternating co‐facial arrangement of aromatic and heteroaromatic substructures.
Molten Salt Storage for Power Generation
Authors: Bauer Thomas , Odenthal Christian , Bonk Alexander 
Published: February 2021

AbstractStorage of electrical energy is a key technology for a future climate‐neutral energy supply with volatile photovoltaic and wind generation. Besides the well‐known technologies of pumped hydro, power‐to‐gas‐to‐power and batteries, the contribution of thermal energy storage is rather unknown. At the end of 2019 the worldwide power generation capacity from molten salt storage in concentrating solar power (CSP) plants was 21 GWhel. This article gives an overview of molten salt storage in CSP and new potential fields for decarbonization such as industrial processes, conventional power plants and electrical energy storage.
Kinetic Resolution of 2‐Substituted 1,2‐Dihydroquinolines by Rhodium‐Catalyzed Asymmetric Hydroarylation†
Authors: Cai Baohua , Yang Qingjing , Meng Ling , Wang Jun Joelle 
Published: February 2021

Main observation and conclusionA highly efficient kinetic resolution of racemic 2‐substituted 1,2‐dihydroquinolines via Rh‐catalyzed asymmetric hydroarylation has been described for the first time. A variety of arylboronic acids coupled with 2‐substituted 1,2‐dihydroquinolines under mild reaction condition. The transformations into the enantio‐enriched 2,3‐diaryl‐tetrahydroquinolines as well as the recovered chiral 2‐aryl‐dihydroquinolines were obtained with high yields and excellent enantioselectivities (86%—99% ee, s factor up to 1057).
Outcomes of sublobar resection vs lobectomy for invasive clinical stage T1N0 non‐small‐cell lung cancer: A propensity‐match analysis
Authors: Wald Ori , Sadeh Bar Moshe , Bdolah‐Abram Tali , Erez Eldad , Shapira Oz Moshe , Izhar Uzi 
Published: February 2021

AbstractBackgroundThe role of sub lobar resection (SLR; either segmentectomy or wedge resection) vs lobectomy (LBCT) for invasive clinical stage T1N0 non‐small‐cell‐lung‐cancer (NSCLC) has not been fully established yet.AimWe aimed to characterize the preoperative parameters leading to selecting SLR and compare the overall survival (OS) and disease‐free survival (DFS) of these two surgical approaches.MethodsClinical data on 162 patients (LBCT‐107; SLR‐55) were prospectively entered in our departmental database. Preoperative parameters associated with the performance of SLR were identified using univariate and multivariate cox regression analysis. The Kaplan‐Meier method was used to compute OS and DFS. Comparison between LBCT and SLR groups and 32 propensity‐matched groups was performed using Log‐rank test.ResultsMedian follow‐up time for the LBCT and SLR groups was 4.76 (Inter‐quartile range [IQR] 2.96 to 8.23) and 3.38 (IQR 2.9 to 6.19) years respectively. OS and DFS rates were similar between the two groups in the entire cohort (OS‐LBCT vs SLR P = .853, DSF‐LBCT vs SLR P = .653) and after propensity matching (OS‐LBCT vs SLR P = .563 DSF‐LBCT vs SLR P = .632). Specifically, Two‐ and five‐year OS rates for LBCT and SLR were 90.6.% vs 92.7%, 71.8% vs 75.9% respectively. Independent predictors of selecting for SLR included older age (P < .001), reduced FEV1% (P = .026), smaller tumor size (P = .025), smaller invasive component (P = .021) and higher American Society of Anesthesiology scores (P = .014).ConclusionsIn 162 consecutive and 32 matched cases, SLR and lobar resection had similar overall and disease‐free survival rates. SLR may be considered as a reasonable oncological procedure in carefully selected T1N0 NSCLC patients that present with multiple comorbidities and relatively small tumors.
Isoperimetry, Scalar Curvature, and Mass in Asymptotically Flat Riemannian 3‐Manifolds
Authors: Chodosh Otis , Eichmair Michael , Shi Yuguang , Yu Haobin 
Published: February 2021

AbstractLet (M, g) be an asymptotically flat Riemannian 3‐manifold with nonnegative scalar curvature and positive mass. We show that each leaf of the canonical foliation of the end of (M, g) through stable constant mean curvature spheres encloses more volume than any other surface of the same area.Unlike all previous characterizations of large solutions of the isoperimetric problem, we need no asymptotic symmetry assumptions beyond the optimal conditions for the positive mass theorem. This generality includes examples where global uniqueness of the leaves of the canonical foliation as stable constant mean curvature spheres fails dramatically.Our results here resolve a question of G. Huisken on the isoperimetric content of the positive mass theorem. © 2021 The Authors. Communications on Pure and Applied Mathematics published by Wiley Periodicals LLC.
Survey on radio resource allocation in long‐term evolution‐vehicle
Authors: Allouch Mariem , Kallel Sondes , Soua Ahmed , Shagdar Oyunchimeg , Tohme Samir 
Published: February 2021

AbstractThe main goal behind radio resource management (RRM), in any conventional wireless networks, is to efficiently utilize the available resources. Critical and safety communications have very stringent quality of service requirements on reliability and availability. Consequently, the efficient use of resources becomes more compelling when it deals with this type of application. In this context, cellular vehicle‐to‐everything (C‐V2X) communications, enabled by cellular device‐to‐device (D2D), have recently drawn much attention. This is due to their applicability to road safety and traffic efficiency applications, which require information exchange among road users and road‐side entities. This emerging technology, referred hereinafter as LTE‐V or C‐V2X, supports two different communication modes: 3 and 4. Both of the two modes enable direct vehicle‐to‐vehicle (V2V) communications via PC5 interface. However, they differ on how the radio resources are allocated. Several approaches and algorithms are proposed in the literature to address the resource allocation issue. In this paper, a state of the art of the radio resource allocation strategies was made for LTE‐V technology and a qualitative description was carried out of these different schemes. We proposed a classification of these strategies into different categories. This classification identified the different strengths and weaknesses of each proposal. Up to our knowledge, several surveys concerning resource allocation are published in the context of LTE but very few of them focuses on both RRM and vehicular networks.