bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute Acromioclavicular Joint Dislocation Stabilized by Mini-Open Double Endo-Button and Fiber Wire System
Authors: Jha Ranjib Kumar , Thapa Santosh , Rajthala Asish 
Published: February 2025

Background: There are different surgical treatment options for acromioclavicular joint dislocation which can be done by open, mini-open or arthroscopically. We aimed to evaluate mini-open double endo-button and fiber wire for stabilization of Rockwood type III, IV and V acromioclavicular joint dislocation.
Materials and Methods: This is a prospective clinical cohort study performed between April 2021 to March 2023. All cases were treated by mini-open double endo-button and fiber wire. Age, sex, injury mechanism, side of injury, time before surgery, duration of hospital stay, constant score, disability of Arm, Shoulder and Hand score (DASH), visual analogue scale (VAS), coracoclavicular distance and complications were recorded during follow up.
Results: Out of 25 cases, 20(80%) were male and 5(20%) were female. The mean age of patients was 33.64±9.83. The mean DASH and constant score were 1.58±1.03 and 93.84±3.15 respectively. There was significant decrease in VAS score. There was no significant difference in coracoclavicular distance between injured and contralateral side. Three cases had residual subluxation.
Conclusion: The mini-open double endo-button and fiber wire technique of fixation is excellent method for dislocated acromoiclavicular joint without any soft tissue dissection around coracoclavicular ligaments.
Abdominal Sacro-Colpopexy Surgery for Vaginal Vault Prolapse at Nobel Medical College Teaching Hospital
Authors: Yadav Munjal , Baral Gehanath 
Published: February 2025

Background: Post-hysterectomy Vault prolapse is an uncommon late complication of hysterectomy. Women often experience restrictions in physical, emotional, and social functioning which decreases the overall quality of life. Vaginal vault prolapse can be treated by pelvic floor muscle training, pessary insertion, and surgery. Abdominal sacro-colpopexy is a procedure that surgically corrects vault prolapse using Prolene mesh to lift and hold the vaginal vault in the correct anatomical position. The study aimed to determine the success rate and complications of Abdominal sacro-colpopexy when performed by an experienced surgeon.
Materials and Methods: Observational descriptive study performed from June 2022 to December 2023 for 18 months at Nobel Medical College Teaching Hospital, Biratnagar, Nepal. All consecutive cases of vault prolapse surgeries were taken. Outcome measures were success rate and the potential complications post-operatively.
Results: The post-hysterectomy vault prolapse surgery was around 1% out of all gynecological surgeries. Most of them were asymptomatic in a median follow-up of 6 months. There were no complications of surgery. Almost all patients resolved their prolapse symptoms well, while none required further surgery.
Conclusion: Abdominal sacro-colpopexy is a safe and effective surgical method for post-hysterectomy vault prolapse.
ОРІЄНТИРИ ПОЛІТИКИ ЗБЕРЕЖЕННЯ ЛЮДСЬКОГО КАПІТАЛУ УКРАЇНИ В УМОВАХ ВІЙНИ
Authors: ГРИГОРУК Павло 
Published: February 2025

The article focuses on the issues of preservation and development of Ukraine's human capital in the conditions of a full-scale war. Emphasis is placed on the existential challenges of the level of national security and stability of Ukraine, such as the rapid and large-scale external migration of Ukrainians, large-scale volumes of internally displaced persons and the actualization of the problems of overcoming the social vulnerability of the population, the destruction of homes and social and housing-communal infrastructure on a large area of the country's territory, the deterioration of the quality of life and significant difficulties and social issues at the stage of post-war reconstruction of our state. That is why the aim of the study was to generalize the sources and consequences of the loss, as well as to determine the guidelines of the state policy of preserving the human capital of Ukraine in the conditions of a full-scale war. It was concluded that the main directions of formation and implementation of the state policy of preserving human capital of Ukraine are: (1) regulation of migration processes and inhibition of migration losses; (2) conducting a proactive policy of overcoming the social vulnerability of the population; (3) elimination of disparities and balancing of the leading characteristics of the functioning of regional labor markets; (4) creation of prerequisites for the growth of business activity of the population, development of entrepreneurship and self-realization; (5) increasing human capital by means of proactive youth policy, especially in the fields of education, science, culture and art. The scientific novelty of the research results lies in the development of a methodical approach to the identification of challenges and threats to the preservation and loss of the country's human potential in war conditions. The practical significance of the research results lies in the development of a system of measures, the implementation of which will allow preserving and increasing the human potential of Ukraine in an environment of aggressive war.
ФОРМУВАННЯ БЮДЖЕТІВ РОЗВИТКУ МІСЦЕВИХ БЮДЖЕТІВ В ПЕРІОД ВОЄННОГО СТАНУ ТА ПОВОЄННОГО ВІДНОВЛЕННЯ
Authors: РОЖКО Олександр , ДЕМИДЕНКО Людмила , НАКОНЕЧНА Юлія 
Published: February 2025

Фінансування повоєнного відновлення територіальних громад потребує значних ресурсів. Місцеві бюджети постраждали найбільше від воєнних дій, оскільки вони втратили суттєву частину джерел надходжень. Пріоритетом став не розвиток, а виживання та відновлення ОТГ. Бюджети розвитку, які повинні бути спрямовані на соціально-економічний розвиток ОТГ, були значно скорочені через брак коштів. У статті проаналізовано основні джерела наповнення бюджетів розвитку місцевих бюджетів, які використовувалися у довоєнний період після початку процесу децентралізації. Досліджено основні зміни законодавства щодо можливих джерел наповнення бюджетів розвитку місцевих бюджетів. Визначено основні напрямки витрат, які можна здійснювати за рахунок бюджетів розвитку. Встановлено, що наразі згідно законодавству основними джерелами наповнення бюджетів розвитку є кошти від використання комунальної власності, концесійні платежі, капітальні трансферти з інших бюджетів і місцеві запозичення. Також, одним з можливих джерел було визначено кошти Державного фонду регіонального розвитку (ДФРР). Аналіз довоєнного функціонування ДФРР показав, що до 2022 року ефективну роботу цього механізму не було налагоджено. Це пояснюється декількома причинами, серед яких відсутність напрацьованого механізму відбору найбільш необхідних проєктів, затримки у фінансуванні, відсутність дієвої методології оцінки проєктів, які подавалися на конкурс. Це призвело до призупинення роботи ДФРР ще до початку воєнних дій. Визначено, що перелік можливих джерел наповнення бюджету розвитку зазнавав постійних змін з моменту затвердження Бюджетного Кодексу. Останні зміни до можливих джерел наповнення бюджетів розвитку датовані лютим 2022 року. Враховуючи початок війни, це означає, що існує реальна потреба в перегляді законодавчого підґрунтя для наповнення цих бюджетів. Одним з можливих напрямів наповнення бюджетів розвитку є ДФРР у новому форматі відповідно до планів його реформування урядом. Іншим можливим шляхом є зміна законодавства для включення зовнішньої донорської допомоги та міжнародних запозичень як джерел наповнення бюджету розвитку. Це дозволить скоротити час, потрібний на відновлення територіальних громад у повоєнний період.
Study of the effect of darbufelone on the anticonvulsant potential of classic antiepileptic drugs
Authors: Цивунін В. В. 
Published: February 2025

Possible way to improve the control of multidrug-resistant epilepsy can be considered the use of drugs from other pharmacological groups as an adjunct to classical antiepileptic drugs (AEDs). One of the promising such medicines is an anti-inflammatory drug with a unique mechanism of action – the dual COX-2/5-LOG inhibitor darbufelone, for which per se a pronounced anticonvulsant effect was previously established.
The aim of the work was to study the effect of the dual COX-2/5-LOG inhibitor darbufelone on the anticonvulsant potential of classical antiepileptic drugs: sodium valproate and carbamazepine.
The study was conducted using 64 albino mice. Acute seizures were modeled by a single injection of the GABAA receptor antagonist pentylenetetrazole. Classical AEDs were administered intragastrically at ED50 and ½ ED50 30 min before pentylenetetrazole: sodium valproate – at doses of 300 and 150 mg/kg, respectively, carbamazepine – at doses of 100 and 50 mg/kg, respectively; darbufelone was administered at a previously determined effective anticonvulsant dose of 100 mg/kg. Pentylenetetrazole was administered at a dose of 80 mg/kg subcutaneously.
It was found that the combination of darbufelone with sodium valproate at ½ ED50 provided a pronounced protective effect on the pentylenetetrazole-induced seizure model, which was verified by the prolongation of the latency period of the first seizures, a decrease in the number and severity of seizures. In addition, the combination of darbufelone with sodium valproate at ½ ED50 also provided protection of mice from death at the level of valproate at a conditionally effective dose, which significantly exceeded the effectiveness of monotherapy with valproate at ½ ED50 and darbufelone per se. Darbufelone also positively modulated the effect of carbamazepine at ½ ED50, not only reducing lethality (at the level of carbamazepine at a conditionally effective dose), but also protecting mice from severe tonic paroxysms, prolonging the latency period of the first seizures and the life span of animals.
Thus, in the model of acute pentylenetetrazole-induced seizures, it was established that darbufelone not only has its own anticonvulsant properties but is also able to enhance the anticonvulsant potential of sodium valproate and carbamazepine in their subeffective doses. The results obtained provide grounds to consider darbufelone as an effective adjuvant anticonvulsant that provides a protective effect under conditions of the experimental equivalent of refractory epilepsy.
Penerapan Model Pembelajaran Berbasis Masalah Materi Kelainan Sistem Gerak pada Manusia terhadap Hasil Belajar Siswa Kelas XI MA
Authors: Annisa Sholihatun , Putra Aminuddin Prahatama , Ajizah Aulia 
Published: February 2025

The purposes of this research were to (1) describe the effect of the application of the problem-based learning model on cognitive learning outcomes of class XI MA students in the matter of Movement System Disorders in Humans, (2) describes the affective and psychomotor learning outcomes of class XI MA students on the subject of Movement System Disorders in Humans using the problem-based learning model. The subjects of this study were students of class XI IPA 2 and XI IPA 3 MAN 3 Banjarmasin. The research method used was quasi-experimental to determine the effect of the problem-based learning model on cognitive, affective, and psychomotor learning outcomes. The research results show (1) The application of the problem-based learning model to material of Movement System Disorders in Humans has a significant effect on the learning outcomes of class XI MA students, namely a symptom sig (2-tailed) value < 0.05, which is 0.000 and the result of cognitive learning processes with the application of the problem-based learning model is in the good category, (2) the affective learning outcomes of student character behavior and social behavior are include in the good to very good category and psychomotor learning outcomes with the application of the problem-based learning model are in the good category. Through this research, we found that there was an effect of applying the problem-based learning model on the subject of Movement System Disorders in Humans on the learning outcomes of class XI MA students
Machine Learning-Based Risk Prediction Model for Loan Applications: Enhancing Decision-Making and Default Prevention
Authors: Chouksey Anchala , Shovon Md Shihab Sadik , Tannier Nikhil Rao , Bhowmik Proshanta Kumar , Hossain Miraz , Rahman Md Shafiqur , Rahman Md Khalilor , Hossain Md Sazzad 
Published: February 2025

The primary objective of this research was to develop a machine learning model for loan application risk prediction that achieves maximum reliability in decision-making while minimizing risks of default. This study focused on credit application risk assessment in the context of the USA finance industry because challenges and opportunities in this industry are unique in their manner. The dataset for this analysis comprises in-depth records of applicants for loans that exhibit a vast range of characteristics of borrowers, credit history, and repayment behaviors. Comprehensive in scope, the rich dataset has variables that span age, earnings, employment status, and locality alongside other crucial finance variables such as credit scores, debt-to-income ratio, and repayment performance. For model selection, we utilized a variety of machine learning algorithms, including Logistic Regression, Random Forest Classifier, and XG-Boost. The Random Forest and XG-Boost models closely aligned with actual data, showing high accuracy. The integration of predictive modeling of advanced levels within loan decision processes has far-reaching consequences on building lender confidence within risk assessments. By using evidence-driven facts through machine learning models, lenders can make better-informed decisions that better reflect greater insight into borrower behavior and attributes of risk. Looking ahead, numerous directions of future research can advance AI capability and AI-based loan risk assessment software. A critical direction is investigating how to use deep learning techniques, which have shown much promise in numerous fields of endeavor through their ability to learn complex nonlinear relationships within large datasets.
Degree of Microbial Contaminants Isolated from Smart Mobile Phones Used by University Students in Bangladesh
Authors: Nabila Ishrat Anzum , Ferdous Most Zannatul , Tasin Tasnima Akhter , Saba Jobaida 
Published: February 2025

Background: Microbial survival capabilities on smartphone surfaces works as a major source of harmful microbial transmission among users.
Objectives: This study sought to determine the microbial growth on the surface of smartphones, used by students of Jahangirnagar University in Bangladesh.
Methodology: This cross-sectional study, from May to August 2021, involved 20 students, where 8 (40%) were females and 12 (60%) were males. The socio-demographic data and information about their phone usage were collected utilizing a self-administered questionnaire. A sterile swab was rotated over the surface of both sides of each smartphone, and moistened with sterile saline. All swabs were cultured on MacConkey Agar and Nutrient Agar and examined for growth. Plates were incubated aerobically at 370C for 48h and identification was done as per standard laboratory procedures.
Results: Out of the total 20 swab samples collected, 16 (80%) of them presented with bacterial growth, and 10 (50%) of them presented with fungal growth. Gram-positive bacteria occurred on smartphones at 89.7%, whereas Gram-negative bacteria were contaminated at 10.03%. The total frequency of one or several micro-organisms on smartphones was 100%. The predominant isolates were Staphylococcus epidermidis (37.1%) and Staphylococcus aureus (37.1%). Other isolates were Klebsiella sp. (5.7%) and Escherichia coli (2.9%). No significant association was found between smartphone contamination and gender, age group, educational level, phone sharing, presence of scratches, use of front cover, and regular cleaning of smartphones.
Conclusion: The study indicated that smartphones used by students are a vehicle for several microorganisms. According to the findings of this study, smartphones have the potential to act as a mode of transportation for various micro-organisms.
Bangladesh Journal of Infectious Diseases, December 2024;11(2):108-114
The association between features of epicardial adipose tissue and the risks of early recurrence after catheter ablation in patients with atrial fibrillation
Authors: Feng Leiyu , Li Liming , Bai Linpeng , Tang Li , Zhao Yintao , Zhao Xiaoyan 
Published: February 2025

BackgroundEpicardial adipose tissue (EAT) remodeling is associated with atrial fibrillation (AF). However, there is limited research on the contribution of EAT to the risk of AF recurrence (AFR). The purpose of this research was to assess the relationship between the risk of AFR after radiofrequency catheter ablation and the volume and attenuation of the EAT.MethodsWe included a total of 123 consecutive individuals who received AF ablation, 31 of whom suffered AFR. The volume and mean density of the whole-heart and periatrial EAT were measured on computed tomography images using four attenuation ranges. The clinical, atrial, and EAT characteristics of patients with and without AFR were compared. Logistic regression was used to identify independent risk factors and to build a model to predict recurrence. The relationship between EAT characteristics and recurrence was analyzed for the subtypes of AF.ResultsThe AFR group had a larger left atrial anteroposterior diameter (47.4 ± 7.4 vs. 43.7 ± 8.0 mm), left–right diameter (78.6 ± 7.9 vs. 74.7 ± 9.1 mm), and volume (145.9 vs. 127.0 mL) than the non-recurrence group (P = 0.021, 0.037, 0.015, respectively). The total EAT volume in the AFR group was significantly larger than that in the non-recurrence group, for both the overall and persistent AF groups (all P &lt; 0.1). The periatrial EAT volume of the AFR group was significantly larger than that of the non-recurrence group for those with persistent AF (P = 0.047, 0.048, 0.048, 0.031 for four attenuation ranges). The total EAT volume and left atrial anteroposterior diameter were independent risk factors for AFR (P = 0.035, 0.045, respectively).ConclusionThe EAT volume and left atrial anteroposterior diameter were of great significance in predicting AFR.
Exploring public attitudes of continuing care retirement communities in China: a sentiment analysis of China’s social media Weibo
Authors: Wang Xuechun , Xia Bo , Chen Qing , Skitmore Martin , Liu Huiming 
Published: February 2025

IntroductionThe traditional family responsibility system faces challenges as China undergoes rapid demographic shifts with an increasingly older population. Recognizing the potential of market-driven senior care, Continuing Care Retirement Communities (CCRCs) have emerged as a significant alternative. However, cultural stigmas and concerns about the quality, services, and health of older adults in these facilities raise questions over their broad acceptance.MethodsThis study examines public sentiment toward CCRCs through sentiment analysis of 1,027,295 pre-processed Weibo posts. Utilizing Natural Language Processing (NLP) combined with fine-grained sentiment analysis and the Term Frequency-Inverse Document Frequency algorithm, the attitudes and emotions reflected in each data point are analyzed, identifying key contributing factors, and exploring the underlying reasons.Results and discussionThe results reveal a predominantly positive sentiment toward CCRCs, emphasizing factors such as the living environment and government involvement. However, areas of concern, such as potential fraud and health and safety issues, remain. These findings both shed light on the public’s acceptance or resistance to CCRCs for stakeholders and highlight the potential of social media analysis in shaping older people’s care perceptions in today’s China.
Working from home and health complaints: on the difference between telework and informal overtime at home
Authors: Mergener Alexandra , Stawarz Nico , Rüger Heiko , Laß Inga 
Published: February 2025

BackgroundWith the increase in the prevalence of working from home (WFH), understanding its impact on health has become more relevant. However, the possibility that health effects may depend on the specific WFH arrangement has largely been ignored in research.ObjectiveThe aim of this study is to offer a differentiated view of WFH by distinguishing between informal overtime at home and telework during recognized working time when assessing its associations with mental and physical health complaints. Moreover, the extent of telework is considered. The study also differentiates the group of WFH non-users by distinguishing between voluntary non-use and employer-directed non-use.MethodsWe apply OLS regression models with clustered standard errors by occupation to probability-based survey data that is representative of employees in Germany. The analytical sample was restricted to employees whose job tasks could be performed at home (N = 10,365).ResultsCompared to employer-directed non-users, working informal overtime at home is associated with more mental health complaints, while telework is associated with fewer mental and physical health complaints. However, the beneficial association between recognized telework and mental health only applies to employees with relatively small extents of telework. At higher extents of telework, the mental health advantages disappear, while those for physical health tend to remain.ConclusionThis study suggests that a nuanced look at patterns of use and non-use of WFH is essential when gauging its impact on health.
Case Report: Synovial chondromatosis in sport climbers fingers
Authors: Becker Helmut , Iruretagoiena-Urbieta Xeber , Schöffl Volker 
Published: February 2025

IntroductionSport Climbing is a rapidly developing sport with an increasing variety and number of injuries, especially now that it is an Olympic event. The objective of this study is to firstly report the presence of Finger Synovial Chondromatosis (FSC) found in the fingers of climbers. Synovial chondromatosis is a rare condition and particularly rare in the hands and fingers.MethodsWe prospectively evaluated all climbers with finger injuries presenting in 2022 for the presence of FSC in the finger joints. 13 patients in this case series were included with complaints of finger pain for more than 6 weeks. The study was performed in our Sports Medical Centre in Bamberg, Germany. The diagnosis was made based on in person clinical assessment, ultrasound examination and additional radiological findings (e.g., x-ray, CT, MRI) as applicable.ResultsWe detected 13 male climbers with FSC with experience ranging from intermediate to elite level. 77% (10/13) of the patients did not complain of any symptoms of the FSC and presented with other diagnoses (e.g.pulley rupture, tenosynovitis) and the finding of FSC was just an additional finding. In 12 subjects FSC was found in the proximal interphalangeal (PIP) joint and one in the metacarpo-pahalangeal (MCP) joint and distributed as follows: right (R) side 69%, left (L) side 38%, considering 15% in both hands. The prevalence corresponded to the digits are as follows: D2 15%, D3 77%, and D4 15%.DiscussionWith the rapid development in sport climbing there has been a rise in the intensity, volume and variety of training, which may be the key factors contributing to the spectrum of injuries associated with climbing. Hand and finger climbing related injuries are well documented, however the incidental discovery of this rare condition warrants its inclusion as another differential diagnosis in the spectrum of climbing related pathologies. At the moment, not enough is understood about FSC and its long-term consequences therefore further analysis is warranted for future studies.