bluuebunny/crossref_metadata_2025_split huggingface dataset:
The multiple meanings of the gender‐inclusive pronoun hen: Predicting attitudes and use
Authors: Renström Emma A. , Lindqvist Anna , Sendén Marie Gustafsson 
Published: October 2021

AbstractThe Swedish gender‐inclusive pronoun hen can be used generically (referring to anyone), or specifically (referring to non‐binary gender identities). Three studies tested evaluations and use of hen, and individual‐level predictors. In Study 1 (N = 2145), specific hen was slightly favoured over generic hen. In Study 2 (N = 297), hen was more negatively evaluated than binary pronouns, and generic hen was more positively evaluated than specific hen. In Study 3 (N = 450), hen was less frequently used compared to binary pronouns overall but preferred in generic contexts. Traditionalism mainly predicted attitudes towards generic hen and beliefs about gender, as binary mainly predicted attitudes towards specific hen, although the pattern varied across studies. Because hen was preferred in generic contexts, but not in specific ones, this work has implications for understanding the non‐acceptance of non‐binary gender identities since the traditional binary notion of gender still is strong.
Bifunctional Nanocomposites Based on SiO2/NiS2 Combination for Electrochemical Sensing and Environmental Catalysis
Authors: Renganathan Vengudusamy , Balaji Ramachandran , Chen Shen‐Ming , Chandrasekar Narendhar , Maheshwaran Selvarasu , Kao C. R. 
Published: October 2021

AbstractDue to a rapid growth in the industrial processing of the large amount of raw materials have caused a severe contamination of dihydroxy benzene‐based isomers and various colored dyes in the environment. For the highly sustainable environment supporting a healthy human life, the development of highly reliable sensor for the determination and elimination of pollutants is of greater importance. Coupling with enhanced sensing performance, the sensor should also be portable, economical and reproducible. Within consideration of the facts, we fabricate a novel electrochemical sensor for the determination of dihydroxy benzene (catechol) based on the bimetallic nanocomposites SiO2/NiS2 (SN). We utilized the amperometric analytical technique for the effective sensing of catechol at the lower concentration. This technique is economical and ultrasensitive to others. The fabricated bimetallic nanocomposites SiO2/NiS2 reinforced electrode showed a good sensitivity 1.719 μA μM−1 cm−2 and limit of detection (LOD) 24.2 nM with the linear range of 0.2 μM to 43.2 μM. Then the bimetallic nanocomposites SN is used for the investigation of removal of methyl orange dye. The SN accelerated the degradation of methyl orange in 8 mins.
Early maladaptive schemas in eating disorders: A systematic review
Authors: Maher Anthea , Cason Liana , Huckstepp Tyrone , Stallman Helen , Kannis‐Dymand Lee , Millear Prudence , Mason Jonathan , Wood Andrew , Allen Andrew 
Published: October 2021

AbstractObjectiveResearch and theory suggest the aetiological nature and symptomatic profile of eating disorders (EDs) can be explained by multiple factors, including the development of early maladaptive schemas (EMS). Yet, there is lack of consensus regarding the evidence supporting the relationship between EMS and EDs. Therefore, this systematic review aimed to examine existing literature concerning the relationship between different ED diagnoses and EMS to provide a synthesis and evaluation of relevant research.MethodA comprehensive literature search of four electronic databases was conducted and studies were included that examined the association between EMS and EDs. Studies were required to use a variant of Young Schema Questionnaire and establish ED diagnosis or symptomology using self‐report questionnaires or clinical interview.ResultsA total of 29 studies were included in the review. Compared to healthy controls and varying clinical populations, individuals with EDs generally reported significantly higher scores across all EMS except for Entitlement. Furthermore, Unrelenting Standards consistently appeared as a significant EMS across all ED diagnoses whilst Insufficient Self‐Control was significantly lower in ED diagnoses with restrictive behaviour compared to diagnoses with binge eating or purging behaviour.DiscussionResearch supports significant associations between EMS and EDs, which may contribute to our understanding of ED aetiology, including different diagnostic categories. This review underscores the need for studies to explore more gender and age diverse samples and highlights important implications for practitioners.
An improved electrochemical‐based model to estimate battery equivalent circuit parameters for pulsed discharge scenarios
Authors: Bhat Chalukya , Channegowda Janamejaya 
Published: October 2021

AbstractLithium‐ion batteries (LIBs) power almost all consumer electronics products these days. High‐energy density and low cost are some of the reasons behind LIBs being used to electrify all modes of transportation. Battery equivalent circuit models enable estimation of the state of battery energy and power. These models also assist in the capturing dynamic and transient operation of electric vehicles (EVs). Researchers have used lumped equivalent circuit models in the past which fail to capture the transient variation of battery capacity during pulsed charging scenarios. In this article, we approach the estimation of battery equivalent circuit parameters from an electrochemical model‐based approach. This is the first research work to employ the single particle model that considers the electrolyte behavior to derive battery equivalent circuit parameters. We evaluate this approach using three different batteries of varying cell capacities. This technique not only improves the accuracy of these models but enables a complete understanding of the transient load operation of these batteries.
Metabolomics study of Angelica sinensis (Oliv.) Diels on the abnormal uterine bleeding rats by ultra‐performance liquid chromatography–quadrupole–time‐of‐flight mass spectrometry analysis
Authors: Chen Ting‐Ting , Zou Liang , Wang Di , Li Wei , Yang Yong , Liu Xiao‐Min , Cao Xin , Chen Jia‐Rong , Zhang Yan , Fu Jia 
Published: October 2021

AbstractThe objective of this study was to explore the effects and underlying intervention mechanisms of Angelica water extract (AWE) on abnormal uterine bleeding (AUB) based on serum metabolomics. Firstly, the concentration of main active substances in AWE was determined and the chemical components were identified by UPLC‐Q‐Exactive Orbitrap‐MS/MS. A drug‐induced abortion model was established by mifepristone and misoprostol. After administration AWE (2.16 g/kg) for 7 days, the coagulation function, serum hormone levels, H&E staining, and immunohistochemistry observation of uterus were detected. In addition, serum metabolites profiles were performed on ultra‐performance liquid chromatography–quadrupole–time‐of‐flight mass spectrometry (UPLC‐Q‐TOF‐MS). The contents of ferulic acid, senkyunolide A, and ligustilide in AWE were 0.7276, 0.0868, and 1.9908 mg/g, respectively. Twenty‐six compounds were identified in AWE. It was found that AWE was effective in regulation of coagulation function and promoting endometrial recovery. Meanwhile, the levels of E2, Pg, and HCG and the expression of ERα, Erβ, and PR were down‐regulated in AUB model and up‐regulated by the treatment of AWE. Twenty‐one potential biomarkers were eventually identified by multivariate statistical analysis. Study indicated that glycerophospholipid, sphingolipid, amino acids, retinol metabolism and primary bile acid biosynthesis were the main related metabolic pathways involved for the treatment of AUB by AWE. The results showed that AWE has potential therapeutic effect on AUB by altering the metabolic aberrations.
Transcriptome sequencing of archived lymphoma specimens is feasible and clinically relevant using exome capture technology
Authors: Skaftason Aron , Qu Ying , Abdulla Maysaa , Nordlund Jessica , Berglund Mattias , Ednersson Susanne Bram , Andersson Per‐Ola , Enblad Gunilla , Amini Rose‐Marie , Rosenquist Richard , Mansouri Larry 
Published: October 2021

AbstractFormalin‐fixed, paraffin‐embedded (FFPE) specimens are an underutilized resource in medical research, particularly in the setting of transcriptome sequencing, as RNA from these samples is often degraded. We took advantage of an exome capture‐based RNA‐sequencing protocol to explore global gene expression in paired fresh–frozen (FF) and FFPE samples from 16 diffuse large B‐cell lymphoma (DLBCL) patients. While FFPE samples generated fewer mapped reads compared to their FF counterparts, these reads captured the same library complexity and had a similar number of genes expressed on average. Furthermore, gene expression demonstrated a high correlation when comparing housekeeping genes only or across the entire transcriptome (r = 0.99 for both comparisons). Differences in gene expression were primarily seen in lowly expressed genes and genes with small or large coding sequences. Using cell‐of‐origin classifiers and clinically relevant gene expression signatures for DLBCL, FF, and FFPE samples from the same biopsy paired nearly perfectly in clustering analysis. This was further confirmed in a validation cohort of 50 FFPE DLBCL samples. In summary, we found the biological differences between tumors to be far greater than artifacts created as a result of degraded RNA. We conclude that exome capture transcriptome sequencing data from archival samples can confidently be used for cell‐of‐origin classification of DLBCL samples.
Sex differences in acute and long‐term brain recovery after concussion
Authors: Churchill Nathan W. , Hutchison Michael G. , Graham Simon J. , Schweizer Tom A. 
Published: October 2021

AbstractConcussion is associated with acute disturbances in brain function and behavior, with potential long‐term effects on brain health. However, it is presently unclear whether there are sex differences in acute and long‐term brain recovery. In this study, magnetic resonance imaging (MRI) was used to scan 61 participants with sport‐related concussion (30 male, 31 female) longitudinally at acute injury, medical clearance to return to play (RTP), and 1‐year post‐RTP. A large cohort of 167 controls (80 male, 87 female) was also imaged. Each MRI session assessed cerebral blood flow (CBF), along with white matter fractional anisotropy (FA) and mean diffusivity (MD). For concussed athletes, the parameters were converted to difference scores relative to matched control subgroups, and partial least squares modeled the main and sex‐specific effects of concussion. Although male and female athletes did not differ in acute symptoms or time to RTP , all MRI measures showed significant sex differences during recovery. Males had greater reductions in occipital‐parietal CBF (mean difference and 95%CI: 9.97 ml/100 g/min, [4.84, 15.12] ml/100 g/min, z = 3.73) and increases in callosal MD (9.07 × 10−5, [−14.14, −3.60] × 10−5, z = −3.46), with greatest effects at 1‐year post‐RTP. In contrast, females had greater reductions in FA of the corona radiata (16.50 × 10−3, [−22.38, −11.08] × 10−3, z = −5.60), with greatest effects at RTP. These findings provide new insights into how the brain recovers after a concussion, showing sex differences in both the acute and chronic phases of injury.
Impact of hybrid nanofluids on unsteady MHD flow and heat transfer due to a moving infinite vertical plate
Authors: Rajesh Vemula , Chamkha Ali J. 
Published: October 2021

AbstractThe objectives of this study are (i) to find exact analytical solutions to the unsteady hybrid nanofluid flow and heat transfer due to a moving infinite flat plate, and (ii) to investigate the impacts of different hybrid nanofluids (Cu‐Al2O3/water, CuO‐Al2O3/water, and Ag‐Al2O3/water) on the unsteady flow and heat transfer characteristics with MHD and variable temperature. The Laplace transform technique is employed to find the exact analytical solutions of the partial differential equations with appropriate boundary conditions governing the problem considered. The results computed for engineering quantities, namely skin friction coefficient and Nusselt number and velocity and temperature profiles by the Laplace transform technique are analyzed using graphs and tables. It has been found that there is a significant increase in the heat transfer rate for hybrid nanofluids than for nanofluids and we observed a higher heat transfer rate for Cu‐Al2O3/water and a lower heat transfer rate for Ag‐Al2O3/water than for the others. The novelty of this study is finding an exact analytical solution to the problem of hybrid nanofluid flow due to moving vertical plate where the effects of magnetic field and variable plate temperature conditions are considered. The obtained results can be used in various engineering applications, including geothermal reservoirs, packed‐bed storage tanks, packed‐bed catalytic reactors, thermal insulation, grain storage, porous solids drying, and petroleum resource gas production. Furthermore, the findings can be used to validate numerical solutions for more complex transient hybrid nanofluid flow and convective heat transfer problems.
The role of microchannel geometry selection on heat transfer enhancement in heat sinks: A review
Authors: Dash Binayak , Nanda Jajneswar , Rout Sachindra Kumar 
Published: October 2021

AbstractExtensive research has been carried out by researchers for improving the thermal efficiency of the microchannel. There are various types of methodologies that have been proposed by authors for different geometry and fluid flow. The use of microchannel in the miniature heat exchangers and microchannel heat sink (MCHS) have taken the science of heat transfer to an another level for which the field of electronic device cooling, aerospace applications, automobile sectors, biomedical engineering, and chemical engineering sectors are being keen toward further development of the technology. Since 3 decades, the microchannel has been tested numerically, experimentally, and analytically for establishing the theories of hydraulic and thermal efficiency during fluid flow. Improper geometry selection of microchannel may lead to carry various losses such as pressure drop, friction factor, wall shear stress, and temperature jump. Available investigations and results have been reviewed immensely in this paper to give a clear prospective for further research in selecting a proper channel geometry.
Adult allergic rhinitis sufferers have unique nasal mucosal and peripheral blood immune gene expression profiles: A case–control study
Authors: Watts Annabelle M. , West Nicholas P. , Smith Peter K. , Cripps Allan W. , Cox Amanda J. 
Published: October 2021

AbstractBackgroundAllergic rhinitis (AR) is a complex disease involving both mucosal and systemic immune compartments. Greater understanding of the immune networks underpinning AR pathophysiology may assist with further refining disease‐specific biomarkers.ObjectiveTo compare immune gene expression profiles in nasal mucosa and peripheral blood samples between adults with AR and controls without AR.MethodsThis cross‐sectional study included 45 adults with moderate‐severe and persistent AR (37.6 ± 12.8 years; mean ± SD) and 24 adults without AR (36.6 ± 10.2). Gene expression analysis was performed using the NanoString nCounter PanCancer Immune profiling panel (n = 730 immune genes) in combination with the panel plus probe set (n = 30 allergy‐related genes) with purified RNA from peripheral blood and cell lysates prepared from combined nasal lavage and nasal brushing.ResultsOne hundred and thirteen genes were significantly differentially expressed in peripheral blood samples between groups (p < .05). In contrast, 14 genes were differentially expressed in nasal lysate samples between groups (p < .05). Upregulation of allergy‐related genes in nasal mucosa samples in the AR group was observed. Namely, chemokines CCL17 and CCL26 are involved in the chemotaxis of key effector cells and TPSAB1 encodes tryptase, an inflammatory mediator released from activated mast cells and basophils. Six differentially expressed genes (DEGs) were in common between the nasal mucosa and blood samples. In addition, counts of specific DEGs in nasal mucosa samples were positively correlated with eosinophil and dust mite‐specific immunoglobulin E (IgE) counts in blood.Conclusions and Clinical RelevanceDistinct gene expression profiles in blood and nasal mucosa samples were observed between AR sufferers and controls. The results of this study also provide evidence for a close interaction between the local site and systemic immunity. The genes identified in this study contribute to the current knowledge of AR pathophysiology and may serve as biomarkers to evaluate the effectiveness of treatment regimens, or as targets for drug discovery.
Comparison of cervical cancer screening results among public and private services in Brazil
Authors: Bispo Pereira Eliseu Henrique , Camilo‐Júnior Deolino João , D’ávilla Solange Correa Garcia Pires , Mattar Neivio José , Xavier‐Júnior José Cândido Caldeira 
Published: October 2021

AbstractObjectiveTo compare the frequency of cervical smear test results between women seen in private and public health services in a medium‐sized city in Brazil.MethodsThis was an observational analytical study analyzing cervical cytologic results over 16 years. Public data were collected from the Brazilian National Health System, and private refers to those collected at private clinics.ResultsThe overall frequency of unsatisfactory/rejected results was higher in public service examinations (odds ratio [OR] 0.05; 95% confidence interval [CI] 0.04–0.06). The same occurred for atypical squamous cells of undetermined significance (ASC‐US) (OR 0.90; 95% CI 0.85–0.95) and atypical squamous cells cannot exclude high grade intraepithelial lesions (ASC‐H) (OR 0.55; 95% CI 0.47–0.64) categories. For low‐grade squamous intraepithelial lesions, the frequency was higher among women from private services (OR 1.39; 95% CI 1.24–1.55). Among women aged 25–64 years, the frequency of high‐grade squamous intraepithelial lesions was higher among women seen in the public service (OR 0.81; 95% CI 0.66–0.99).ConclusionBrazilian public services showed higher frequencies of unsatisfactory/rejected results and higher rates of ASC‐US and ASC‐H. Focusing on pre‐analytical phases and establishing an internal quality control program can help improve these rates even though national protocols guide them.
Thymoquinone and quercetin induce enhanced apoptosis in non‐small cell lung cancer in combination through the Bax/Bcl2 cascade
Authors: Alam Shoaib , Mohammad Taj , Padder Rayees A. , Hassan Md. Imtaiyaz , Husain Mohammad 
Published: October 2021

AbstractThe treatments available for non‐small cell lung cancer exert various side effects in patients, and the burden of treatment cost is high. Therefore, exploring the alternative system of medicines, including therapies based on natural compounds, has become inevitable in developing anticancer therapeutics. This study used an integrated approach involving in‐silico and in‐vitro methods to explore natural compounds targeting Bax and Bcl2 for their apoptotic potential. Molecular docking followed by molecular dynamics (MD) simulation of thymoquinone (Tq) and quercetin (Qu) with Bax and Bcl2 were carried out to explore their interactions and stability under explicit solvent conditions. Tq and Qu showed appreciable binding affinities toward Bax (−6.2 and −7.1 kcal/mol, respectively) and Bcl2 (−5.6 and −6.4 kcal/mol, respectively) with well‐organized conformational fitting compatibility. The MD simulation results revealed the development of stable complexes maintained by various noncovalent interactions that were preserved throughout the 100 ns trajectories. Further studies with these compounds were carried out using various in‐vitro experimental approaches like MTT assay, apoptotic assay, and Western blot. IC50 values of Tq and Qu alone in A549 cells were found to be 45.78 and 35.69 µM, while in combination, it comes down to 22.49 µM, which is quite impressive. Similarly, in apoptosis assay, a combination of Tq and Qu shows 50.9% early apoptosis compared to Tq (40.6%) and Qu (33.3%) when taken alone. These assays signify their apoptotic induction potential, whereas both compounds significantly reduce the expression of antiapoptotic protein Bcl2 and induce proapoptotic Bax, suggestive of sensitizing NSCLS cells toward apoptosis.
Preparing for 2070: Reflections from the Journal of Community Psychology's initial decade: Pathways to community psychology's continuing maturation
Authors: Lorion Raymond P. 
Published: October 2021

AbstractThis virtual monograph celebrates the 50 th anniversary of the Journal of Community Psychology (JoCP) by reprinting selected commentaries and peer‐reviewed papers from JoCP's initial decade. Selected articles focused on the originating goals and priorities of the discipline of community psychology. Each article is followed by reflections. The monograph final section challenges contemporary discipline leaders to identify goals for the coming decades and milestones for measuring progress in their achievement.
Separation of PET and PS from PET/PS/PP plastic mixture and their use in synthesis of composite floating sorbent materials for dyes removal
Authors: Tsave Polyxeni K , Bikiaris Dimitrios N , Lazaridis Nikolaos K 
Published: October 2021

AbstractBACKGROUNDThe large production of polymeric materials worldwide and the difficulty of their decomposition make recycling necessary for both economic and environmental reasons. In this study, the separation of polyethylene terephthalate (PET) and polystyrene (PS) from ternary mixtures (polyethylene terephthalate/polystyrene/polypropylene, PET/PS/PP) and their subsequent utilization as sorbent materials was carried out. The carbonaceous sorbent materials based on polymeric matrices that were synthesized and characterized have low densities, resulting in ease of removal by flotation.RESULTSWetting agents polyvinyl alcohol (PVA) and dodecylamine (DA) were used to selectively wet PET and PS, respectively, and the effect of the wetting agents' concentration and pH on the effectiveness of the separation were studied. The recovered polymers were then utilized to prepare carbon composite materials that were used to remove of a test dye, Reactive Black dye, from aqueous solutions.CONCLUSIONThe results show effective dye removal (nearly 98%) for both composite materials. The sorbents may then be regenerated for further wastewater treatment. © 2021 Society of Chemical Industry (SCI).