bluuebunny/crossref_metadata_2025_split huggingface dataset:
Training students from rehabilitation professions on communicating with patients with communication disorders
Authors: Mach Helen , Baylor Carolyn , Burns Michael , Yorkston Kathryn 
Published: February 2021

AbstractBackgroundFRAME, a mnemonic referring to a program for helping health care providers adapt patient–provider communication when working with patients with communication disorders, improves the knowledge, confidence, and communication skills of medical students for working with this population. However, the impact of the FRAME program for preparing students from the rehabilitation disciplines to work with patients with communication disorders is unknown.ObjectiveTo examine the effects of the FRAME program on the knowledge, confidence, and communication skills of students in physical therapy (PT), occupational therapy (OT), and prosthetics and orthotics (P&O) in terms of how to communicate effectively with patients with communication disorders.DesignAn exploratory, quasi‐experimental pretest‐posttest design.SettingPT, OT, and P&O clinical education programs at the University of Washington's Department of Rehabilitation Medicine.ParticipantsTwenty rehabilitation students (PT = 12; OT = 7; and P&O = 1) participated in the FRAME training.InterventionsThe FRAME program, delivered in a single, 2‐hour session teaches students communication skills to use with patients with various types of communication disorders.Main Outcome MeasuresA quiz of students' knowledge about communication disorders and a self‐rating of confidence for interacting with this patient population were used. Speech‐language pathology graduate clinicians rated students' use of communication strategies from each area of the FRAME training during interactions with standardized patients portraying aphasia and dysarthria. Student qualitative feedback were also collected.ResultsStudents' knowledge, confidence, and use of communication strategies improved significantly following training. Greatest gains were observed in students' ability to familiarize themselves with how a patient communicates and establish a method of communication before proceeding with the interview. Qualitative feedback aligned with these findings.ConclusionsThe FRAME program increases the knowledge, confidence, and use of communication strategies in rehabilitation students in order to communicate more effectively with patients with communication disorders in their future careers.
Polyimides with low coefficient of thermal expansion derived from diamines containing benzimidazole and amide: Synthesis, properties, and the N‐substitution effect
Authors: Qian Guangtao , Dai Fengna , Chen Haiquan , Wang Mengxia , Hu Mengjie , Chen Chunhai , Yu Youhai 
Published: February 2021

AbstractThree novel diamines, incorporating benzimidazole and amide moieties, namely 4‐amino‐N‐(5‐amino‐benzimidazol‐2‐yl)‐benzamide (6a), 4‐amino‐N‐(5‐amino‐1‐ methyl‐benzimidazol‐2‐yl)‐benzamide (6b), and 4‐amino‐N‐(5‐amino‐1‐phenyl ‐benzimidazol‐2‐yl)‐benzamide (6c), were designed and synthesized. A series of poly(benzimidazole‐amide‐imide) (PBIAI) films were prepared from the resulting diamines and 4,4‐biphthalic dianhydride (BPDA). These flexible polyimides (PIs) showed high glass transition temperatures (Tg = 353–379°C), low coefficients of thermal expansion (CTE = 3.7–12.3 ppm K−1) and good mechanical properties (σ = 152–207 MPa and E = 4.5–7.7 GPa), promising candidates for applications in flexible‐display substrates. Furthermore, the data guided a feasible method to enhance Tg and reduce CTE by introducing benzimidazole and amide units into PI main chains, and the effect of different N‐substituents on performance was revealed.
Wiener polarity index and related molecular topological descriptors of titanium oxide nanotubes
Authors: Imran Muhammad , Malik Mehar Ali , Javed Ramsha 
Published: February 2021

AbstractThe relations between the physico‐chemical properties of a chemical compounds its molecular structure properties are used in quantitative structure activity and property relationship studies by using graph‐theoretical techniques. The Wiener polarity index is the number of unordered pairs of vertices lying at distance3in a graph. This index is correlated to the cluster coefficient of chemical networks. The Wiener polarity index has been used to exhibit quantitative structure–property relationships in a series of acyclic and cycle‐containing hydrocarbons. In this paper, we consider three variants of the graph of titanium oxideTiO2, that is, two‐dimensional lattice, nanotubes and nanotorus. For all these graphs, we compute the number of pairs of vertices lying at distance one, two and three. Using this information, we compute the Wiener polarity index and leap Zagreb indices of these graphs.
Adaptive decentralized sensor failure compensation control for nonlinear switched interconnected systems with average dwell time
Authors: Zhang Jing , Xiang Zhengrong 
Published: February 2021

AbstractIn this article, we investigate the adaptive decentralized output feedback sensor failure compensation control issue of nonlinear switched interconnected systems. A new switched state observer is designed based on the false state information for estimating unmeasured states. To address the challenges incurred by the partial loss of the effectiveness of sensors, a novel adaptive failure compensation mechanism containing error signals is adopted. Mode‐dependent adaptive laws that can explicitly reflect switchings of the system are designed. A decentralized adaptive failure‐tolerant controller is constructed by using backstepping technique. It is proved that the presented scheme can guarantee that the system outputs track the reference signals and all signals in the closed‐loop system are bounded with average dwell time switchings. A practical simulation example is provided to illustrate the effectiveness of the presented scheme.
An integrated satellite–terrestrial 5G network and its use to demonstrate 5G use cases
Authors: Evans Barry , Wang Ning , Rahulan Yogaratnam , Kumar Satish , Cahill Joe , Kavanagh Mark , Watts Simon , Chau Duy‐Kha , Begassat Yann , Brunel Alain‐Pierre , Masson Thierry , Diarra Mamoutou 
Published: February 2021

SummaryIn this paper, we present a satellite‐integrated 5G testbed that was produced for the EU‐commissioned Satellite and Terrestrial Networks for 5G (SaT5G) project. We first describe the testbed's 3GPP Rel. 15/6‐compliant mobile core and radio access network (RAN) that have been established at the University of Surrey. We then detail how satellite NTN UE and gateway components were integrated into the testbed using virtualization and software‐defined orchestration. The satellite element provides 5G backhaul, which in concert with the terrestrial/mobile segment of the testbed forms a fully integrated end‐to‐end (E2E) 5G network. This hybrid 5G network exercised and validated the four major use cases defined within the SaT5G project: cell backhaul, edge delivery of multimedia content, multicast and caching for media delivery and multilinking using satellite and terrestrial. In this document, we describe the MEC implementations developed to address each of the aforementioned use cases and explore how each MEC system integrates into the 5G network. We also provide measurements from trials of the use cases over a live GEO satellite system and indicate in each case the improvements that result from the use of satellite in the 5G network.
Investigating the Influence of Reflux Condensation Reaction Temperature on the Growth of FeCo2O4 Thin Film for Flexible Supercapacitor
Authors: Kamble Gokul , Kashale Anil , Rasal Akash , Dengale Suraj , Kolekar Sanjay , Chang Jia Yaw , Han Sung‐Hwan , Ghule Anil 
Published: February 2021

AbstractMetal oxides are at the forefront for supercapacitors (SCs) applications considering their unique properties like rapid charge transport and ability to provide more active sites. In this respect, FeCo2O4 nanostructures with varying morphology are designed by reaction temperature variations (80, 100, 120, and 140 °C) in facile reflux condensation synthesis. These different structures are grown onto the flexible stainless‐steel mesh (FSSM) and investigated as an electrode in SCs. FeCo2O4 prepared at 120 °C shows good electrochemical performance and offers 106.85 m2/g specific surface area, 0.1531 cc/g pore volume, and demonstrate hierarchical mesoporous construction. FeCo2O4 nanoflakes demonstrate 260 F g−1 specific capacitance at 1 mA cm−2 and 96.16 % retention of capacitance (over 1000 cycles) supporting considerable cycle stability. The asymmetric supercapacitor (ASC) device demonstrates 15.27 Wh kg−1 energy density and promising charge‐discharge stability (80 % retention up to 2000 cycles).
Hybrid Compounds Containing a Ferrocene Scaffold as Potential Antimalarials
Authors: Peter Sijongesonke , Morifi Eric , Aderibigbe Blessing A. 
Published: February 2021

AbstractMalaria is an infectious disease, and it remains a serious health problem globally. The drugs developed for its treatment suffer from several shortcomings such as low water solubility, poor bioavailability, drug toxicity, and resistance. Molecular hybridization of different bioactive agents is a promising approach for developing hybrid compounds with improved therapeutic effects. Ferrocene, an organometallic, has been hybridized with several pharmacophores resulting in compounds with potent biological activities. In this research, a modified ferrocene scaffold was hybridized with selected pharmacophores. The synthesized compounds were characterized by Fourier‐Transform Infrared Spectroscopy (FTIR), Nuclear Magnetic Resonance Spectroscopy (NMR), and Liquid Chromatography‐Mass Spectroscopy. The hybrid compounds were obtained in good yields (53–76 %). In vitro evaluation against NF54 (drug‐sensitive) strain of Plasmodium falciparum parasites revealed the compounds, 16 and 19 (hybrids containing artesunate scaffold), together with 18 and 21 (hybrids containing oleanolic acid scaffold), as promising antimalarial agents. These compounds displayed IC50 values of 116.73±3.18, 56.33±15.20, 78.22±21.05, and 58.22±15.20 nM, respectively. These findings revealed the potency of ferrocene as a precursor for the development of promising antimalarials.
Autocatalytic Friedel‐Crafts Acylation of Arenes without Additional Catalyst and Additive
Authors: Zhao Zhe , Tian Xinzhe , Tang Peichen , Ren Yun‐Lai , Zhao Shuang , Zheng Xianfu , Cheng Xinqiang 
Published: February 2021

AbstractA new and autocatalytic method was developed for Friedel‐Crafts acylation of arenes without additional catalyst and additive. A series of electron‐rich arenes underwent the acylation to give the targeted product in low to high yields by using aryl, alkyl and vinyl acyl chlorides as the acylating reagent, which gave an effective method for the preparation of diaryl ketones, alkyl aryl ketones and α,β‐unsaturated ketones. Preliminary mechanistic investigation suggested that the present acylation displayed an induction period and a sigmoid kinetic profile characteristic of autocatalytic systems, and the resulting H+ played a role of the catalyst.
Economic freedom, pandemics, and robust political economy
Authors: Candela Rosolino A. , Geloso Vincent 
Published: February 2021

AbstractWhat is the relationship, if any, between economic freedom and pandemics? This paper addresses this question from a robust political economy approach. As is the case with recovery from natural disasters or warfare, a society that is relatively free economically offers economic actors greater flexibility to adapt to pandemics. We argue that societies that are more economically free will be more robust to the impact from pandemics, illustrated by shorter time for economic recovery. We illustrate this relationship by testing how initial levels of economic freedom (at the start of the major influenza pandemics of the 20th century) temper contractions and accelerate recoveries for 20 OECD countries.
Evaluating the robustness of self‐consolidating concrete: An approach to the mix design procedure
Authors: Rissardi Cristyan Zenato , Gil Augusto Masiero , Ehrenbring Hinoel Zamis , Li Zongjin , Tutikian Bernardo Fonseca 
Published: February 2021

AbstractThis paper aimed to develop a method to analyze and rank self‐consolidating concrete (SCC) according to its robustness, considering isolated and simultaneous variations in its main components, like water (±6%) and cement content (ΔC±), in three matrices with binder to aggregate ratio (rich, intermediate and poor). In the experimental campaign, only water variations (±6%) were considered, and the cement content variations were considered in the analytical method. The method regarded the behavior of SCC in fresh and hardened states and turned out to be potentially useful to the academic community and the industry. The simple additive weighting method was used for that reason, which is probably the most adopted among methods for decisions with multiple variables due to its simplicity. Among the families studied, the poor mixture presented the lowest robustness with variation in water content due to the higher initial w/c ratio. However, for the condition ΔC±, the poor mixture achieved the second‐best robustness index. The rich mixture behaved differently as it was ranked second for ±6% of water and the worst for ΔC± due to slump‐flow and segregation results. The intermediate matrix presented the highest robustness in both conditions analyzed, water (±6%), and cement content (ΔC±).
Utilizing a maximin optimization approach to maximize system resiliency
Authors: Liaghati Hassan Robert , Mazzuchi Thomas A. , Sarkani Shahram 
Published: February 2021

AbstractComplex systems typically have a large parameter space and by definition have the potential for strong emergent behavior, especially when operating in a complex environment. A method is needed to design a system that will be resilient in a complex target operating environment. Here, we propose a maximin optimization approach to support the exploration of system design, based on co‐evolutionary system/environment models, which emphasizes the importance of the operating environment in the system evolution, resulting in increased system resilience. In this paper, this method is demonstrated on an air defense system and shows an increase in resilience when compared to the system resulting from the application of a genetic algorithm such as has been previously demonstrated for other systems. For the air defense system used here, the proposed maximin optimization process significantly (, via a one‐sided paired t‐test) increased the resulting system resilience from 0.64 (the resilience of the system designed by a genetic algorithm) to 0.92 (the resilience of the system designed by maximin optimization).
Targeted Reading Instruction: Four Guiding Principles
Authors: Aiken Heather H. , Bratsch‐Hines Mary , Amendum Steve , Vernon‐Feagans Lynne 
Published: February 2021

AbstractThis article describes four key principles from Targeted Reading Instruction (TRI, formerly called Targeted Reading Intervention), an evidence‐based early reading intervention and professional development program. Focused on accelerating the growth of students not yet meeting grade‐level expectations, one‐on‐one 15‐minute daily TRI lessons engage students in developing phonemic awareness, phonics knowledge, decoding, fluency, vocabulary, and beginning reading comprehension. Four key principles guide TRI, which can be applied to classroom reading instruction. First, all work is done in the context of real words and connected text, placing meaning at the heart of instruction. Second, lessons keep it moving, as they follow a consistent structure, use activities to achieve multiple objectives, and make use of all available resources. Third, TRI teachers let the student do the work, engaging students in productive struggle. Fourth, explicit teaching of skills such as blending provides students with unique strategies to become confident independent readers.
Investigation of cardiorespiratory effects of the selective 5‐HT4 agonist BIMU‐8 in etorphine‐immobilised goats (Capra aegagrus hircus) in a randomized, blinded and controlled trial
Authors: Tod Nadine , Stalder Gabrielle , Rauch Hanna , Boehmdorfer Stefan , Haw Anna , Gerritsmann Hanno , Painer Johanna , Meyer Leith 
Published: February 2021

AbstractBackground: Opioid‐induced respiratory compromise remains a significant challenge in etorphine‐immobilised wildlife. Serotonergic agonists offer a potential avenue for preventing or treating opioid‐induced respiratory compromise. We therefore aimed to determine whether the selective 5‐hydroxytryptamine receptor 4 (5‐HT4) agonist, BIMU‐8, reverses opioid‐induced respiratory compromise in etorphine‐immobilised goats.Methods: Seven healthy adult goats were immobilised with etorphine, then treated with BIMU‐8 or sterile water 5 minutes later in a randomised, prospective cross‐over study. Cardiorespiratory variables were measured at 1‐minute intervals from 4 minutes before etorphine to 15 minutes after its administration. Arterial blood gas analyses were also performed before and after etorphine administration and the respective treatments.Results: Intravenous injection of BIMU‐8 attenuated etorphine‐induced respiratory compromise, as indicated by improvements, compared to baseline and between treatments, in respiratory rate (fR), peripheral arterial blood oxygen saturation (SpO2), partial pressure of arterial oxygen (PaO2) and the alveolar‐arterial oxygen partial pressure gradient (P(A‐a)O2). BIMU‐8 caused an increase in heart rate and a temporary decrease in arterial blood pressure. Mild movements and slight muscle spasm occurred but BIMU‐8 did not reverse immobilisation.Conclusion: Our results indicate that BIMU‐8 may be a potential drug candidate for the treatment, or prevention, of etorphine‐induced respiratory compromise in immobilised ungulates.
Infrastructure‐scale sustainable energy planning in the cityscape: Transforming urban energy metabolism in East Asia
Authors: Taminiau Job , Byrne John , Kim Jongkyu , Kim Min‐whi , Seo Jeongseok 
Published: February 2021

AbstractTransformation of the urban energy metabolism is possible when sustainable energy is positioned as an infrastructure‐scale tool. A review of urban energy planning research is complemented by an examination of assessment methods in use to gauge the feasibility of planning sustainable energy as a new infrastructure to power cities. A case study analysis of the city of Daejeon is offered to operationalize this planning strategy. In particular, the integrated application of the “savings city” and “solar city” concepts where, respectively, citywide deployment of energy efficiency and rooftop photovoltaic energy systems is envisioned at a large‐scale, is explored for Daejeon through the innovative use of geospatial assessment methods and a visualization tool that can guide urban policy. This assessment and its visualization illustrates not only grid energy use divisions throughout the city but also reveals possible energy planning trajectories in pursuit of positioning sustainable energy as urban infrastructure. The assessment finds that cities like Daejeon could fulfill over half of their electricity service needs through in‐city deployment of sustainable energy at the infrastructure‐scale. Cities that embark on this “sustainable city” trajectory essentially reform the lived experience of “the city” and reshape the city‐energy relationship.This article is categorized under:
Energy Efficiency > Systems and Infrastructure
Energy Policy and Planning > Systems and Infrastructure
Energy and Urban Design > Systems and Infrastructure
Breeding program in rehabilitated bottlenose dolphins (Tursiops truncatus gephyreus) from the Southwestern Atlantic Ocean
Authors: Loureiro Julio D. , Migliorisi Ana L. , Loureiro Juan P. , Rodríguez Heredia Sergio , Rebollo Jorge , Álvarez Karina C. , Morón Sergio , Nuñez Favre Romina 
Published: February 2021

AbstractTursiops truncatus gephyreus is only found in the inshore waters of the Southwestern Atlantic Ocean. They are organized in small socially, structured groups, which lead to low genetic variability and high anthropogenic threats. Currently, the information about their reproductive biology and management is still insufficient. Thus, this study aims to present novel information recorded for 20 years regarding reproductive parameters in a small population of captive T. t. gephyreus. Three of the animals involved were found stranded in La Plata River estuary and, the other two were born at the oceanarium. Thirteen semen evaluations showed high‐quality semen with a low percentage of sperm abnormalities. Twelve pregnancies and parturitions were observed. There was a clear calving seasonality during austral spring and summer. The duration of phase‐2 of labor was approximately 80 min, being the caudal presentation the most frequent. The average inter‐birth interval (IBI) was about 33 months. This is the first report that closely monitored parturition, IBI, and seminal evaluation in this species. Information gathered during this program will allow the development of adequate conservation plans for free‐ranging populations.
If time were a graph, what would evolution equations look like?
Authors: Hussein Amru , Mugnolo Delio 
Published: February 2021

AbstractLinear evolution equations are considered usually for the time variable being defined on an interval where typically initial conditions or time periodicity of solutions is required to single out certain solutions. Here, we would like to make a point of allowing time to be defined on a metric graph or network where on the branching points coupling conditions are imposed such that time can have ramifications and even loops. This not only generalizes the classical setting and allows for more freedom in the modeling of coupled and interacting systems of evolution equations, but it also provides a unified framework for initial value and time-periodic problems. For these time-graph Cauchy problems questions of well-posedness and regularity of solutions for parabolic problems are studied along with the question of which time-graph Cauchy problems cannot be reduced to an iteratively solvable sequence of Cauchy problems on intervals. Based on two different approaches—an application of the Kalton–Weis theorem on the sum of closed operators and an explicit computation of a Green’s function—we present the main well-posedness and regularity results. We further study some qualitative properties of solutions. While we mainly focus on parabolic problems, we also explain how other Cauchy problems can be studied along the same lines. This is exemplified by discussing coupled systems with constraints that are non-local in time akin to periodicity.
Regulation of tamoxifen sensitivity by the PLAC8/MAPK pathway axis is antagonized by curcumin-induced protein stability change
Authors: Mao Misha , Hu Dengdi , Yang Jingjing , Chen Yongxia , Zhang Xun , Shen Jianguo , Teng Rongyue , Zhou Jichun , Wang Linbo 
Published: February 2021

AbstractTamoxifen resistance remains the major obstacle to the estrogen receptor positive breast cancer endocrine therapy. Placenta-specific 8 (PLAC8) has been implicated in epithelial-mesenchymal transition and tumorigenesis. However, the molecular mechanisms underlying PLAC8 function in the context of tamoxifen resistance are unclear. Curcumin has attracted considerable attention in the last decades. It is isolated from Curcuma longa and has beneficial effects in cancer therapy. We studied this property by using MCF-7 and tamoxifen-resistant breast cancer cells (MCF-7/TAM) cell lines. PLAC8 can regulate MCF-7/TAM cell drug sensitivity through the MAPK/ERK pathway and shows the potential effects of curcumin or as a possible druggable target against tamoxifen failure.