bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hemorrhagic complications of а novel coronavirus infection: actual clinical problem.
Authors: Симарова И.Б. , Переходов С.Н. , Буланов А.Ю. 
Published: September 2021

Гиперкоагуляционный характер коагулопатии, ассоциированной с новой коронавирусной инфекцией COVID-19, и высокий риск связанных с этим тромботических осложнений — хорошо известный факт на сегодняшний день. Тем не менее в литературе имеются описания и геморрагических событий у больных COVID. В обзоре приведен анализ публикаций, описывающих кровотечения при коронавирусной инфекции; общая частота их в среднем составляет 4–8%. Превалируют желудочно-кишечные кровотечения, существенную часть составляют межмышечные гематомы и кровоизлияния в кожу и слизистые. Показана предиктивная роль применения антикоагулянтов в терапевтических дозах и гипофибриногенемии. Отмечено отсутствие четкого понимания патофизиологических механизмов.
Hypercoagulable character of coagulopathy associated with the novel coronavirus infection COVID-19, and the high risk of associated thrombotic complications is a well-known fact. However, there are also case reports of hemorrhagic events in COVID patients in the literature. The review summarizes the publications describing bleedings in coronavirus infection; their overall frequency is on average 4–8%. Gastrointestinal bleeding are prevalent, intermuscular hematomas and hemorrhages in the skin and mucous membranes are frequent. The predictive role of anticoagulants use in therapeutic doses and hypofibrinogenemia is shown. The absence of clear understanding of the pathophysiological mechanisms is noted.
Clinical cases of eculizumab use as a part of complex therapy in patients with severe COVID-19.
Authors: Майер Р.А. , Бакиров Б.А. , Набиева А.А. , Кудлай Д.А. 
Published: September 2021

Введение. В последние 2 года серьезной проблемой для всего мирового сообщества стало распространение новой коронавирусной (CoV) инфекции COVID-19 (COrona VIrus Disease-2019). Ввиду сложившихся событий в лечении COVID-19 активно стали применяться новые молекулы и уже зарегистрированные лекарственные препараты, доказавшие свою эффективность при других заболеваниях. Цель исследования: оценить эффективность применения препарата экулизумаб у пациентов с тяжелой формой течения COVID-19. Материалы и методы. Проанализированы 3 клинических случая применения препарата экулизумаб в составе комплексной терапии у пациентов с тяжелой формой течения COVID-19. Для оценки эффективности лечения проводился мониторинг основных клинико-лабораторных показателей, а также показателей, характеризующих воспалительный процесс при коронавирусной инфекции: общий анализ крови, биохимический анализ крови, проанализированы уровни таких показателей как ферритин, С-реактивный белок, интерлейкин-6, лактатдегидрогеназа и мембраноатакующий комплекс. Результаты. На фоне проводимой терапии выявлено снижение концентрации основных маркеров воспаления относительно исходных значений. Заключение. Комплексная терапия, включающая экулизумаб, облегчает течение заболевания, позволяет сократить длительность пребывания пациентов в отделении реанимации и интенсивной терапии, укорачивает срок их пребывания на искусственной вентиляции легких, тем самым снижая процент летальности.
Background. In the past two years, the incidence of the novel coronavirus (CoV) infection COVID-19 (COrona Virus Disease-2019) has been a serious problem for the global community. Considering these circumstances, new molecules and already registered drugs that have proven their effectiveness in other diseases, began to be actively used in COVID-19 treatment. Objectives: to assess the effi cacy of eculizumab in patients with severe COVID-19. Patients/Methods. Three clinical cases of eculizumab use as a part of complex therapy in patients with severe COVID-19 have been analyzed. To assess the treatment efficacy, the main clinical and laboratory parameters and indicators of inflammatory process in coronavirus infection were monitored (clinical blood analysis, biochemical blood test, levels of ferritin, C-reactive protein, interleukin-6, lactate dehydrogenase and membrane attack complex). Results. Under the therapy we found the reduction of concentration of the main inflammation markers relative to the initial values. Conclusions. Complex therapy with eculizumab facilitates the course of the disease, reduces the stay duration of patients in the intensive care unit, shortens the period of artificial lung ventilation, thereby reducing the mortality rate.
The Level of Dependency of The Lecturers of Salahaddin University On The New Media
Authors: Ali Jwan Bahaden , Mustaffa Abdulkhalq Ibrahim 
Published: September 2021

The aim of this study that to expose the level of dependency of the lecturers of Salahuddin University on the new media, generally, in education process and determine their use of these tools and determinie the arithmetical average of these uses. For this purpose, specific criteria have been set for measuring the level of dependency , after identifying the Face validity and consistency of the measurement content, the researchers distributed randomly (50) questionnaires to the lectures who were (33) males and 17 females.
the results showed that the lectures depend on new media on medium, that lectures depend on new media for e-mail and the Internet to conduct their research as the ferst recuer, in contrast lectures less depend on new media for getting information about the goods they want to buy or to choose the fashion and type of clothing.
Impact of Climate Change on Walnut Production in Biara Sub-District
Authors: Ghafur Pshtiwan Gharib , Hama Zhyan Sleman , Tofiq Khanda Saed 
Published: September 2021

In this research is conducted about the impact of climate change on walnut production in Biara Sub-district. Descriptive – analytical method was utilized to obtain the proposed objectives by using SPSS – 16. The predominant objective of this analysis is to illustrate the inevitable impact of climate change on the walnut production in 1973-2017. The results on which the study was based on are Pearson Correlation which demonstrates that there is an indirect correlation between temperature and walnut production, and an equivalent relation with precipitation. For instance, in Multiple Regression Analysis, the impact of temperature and precipitation on small walnut trees is 4%, and on medium walnut trees is 25.8%, whereas on big walnut trees it is 24.8%. Moreover, in Coefficient of Determination, the effect of temperature on small walnut trees is 3.4%, on medium and large walnut trees increase to 18.6% and 24.7% respectively. However, precipitation impact is less than 1%, except medium walnut trees is less than 6%. The apparent wide gaps between temperature and precipitation which affects production is due to low topographic elevation and the presence of 82 springs in the study area.
Additionally, an increase in temperature, a decrease in precipitation and subfreezing temperatures, in other words, chill dates, in spring time, ultimately leads to an increase in hazardous insects such as stem worms and beetle. These issues could be solved through selecting different varieties of walnuts and planting at higher elevation, construct more irrigation projects and regular irrigation, in particular during drought seasons, improving agricultural facilities and importing sufficient pesticides to tackle walnut trees diseases, is also among the precautionary methods.
Attenuation of Staphylococcus Aureus By Pomegranate Peel Extracts
Authors: Ismaeil Abdulilah Saleh , Salih Fraidoon Abdulqadr 
Published: September 2021

Pomegranate Peel extractions used as quorum sensing inhibitor (QSI) against Staphylococcus aureus (which isolated from soft white cheese in local market), different solvents used to obtain different active ingredient groups, minimum inhibitory concentration of each group were determined then sub-inhibitory concentration was used as (QSI). We get that all groups have ability to inhibit quorum sensing in Staphylococcus aureus in different ratio. By using Real-time PCR found that the different Pomegranate Peel extract groups can inhibit the expression of some quorum sensing and virulence factor genes ( Sea, Seb, AgrA, RNAIII, and Hla).
Also Pomegranate Peel extracts groups have a role in biofilm reduction in Staphylococcus aureus significantly, furthermore the extract groups significantly affect the growth curve of this bacteria. Our results idicated that the pomegranate peel extracts fight infections by supressing virulence factors, may be due to blocking autoinducer receptors.
USAHA PENINGKATAN PRODUKSI PADI FUNGSIONAL MELALUI APLIKASI TEKNOLOGI TEPAT GUNA DI DESA KATENG KABUPATEN LOMBOK TENGAH
Authors: Suliartini Ni Wayan Sri , Ngawit I Ketut , Farida Nihla , Anugrawati Dwi Ratna 
Published: September 2021

Keterbatasan fasilitas irigasi memaksa petani mengolah lahan tergesa- gesa untuk mendapatkan air yang cukup, akibatnya proses pelumpuran tanah tidak sempurna, potensi tanah sebagai seed bank sehingga muncul masalah gulma yang sulit dikendalikan. Petani menanam bibit yang tersedia di pasaran tanpa menelusuri asal-usul benih, varietas dan mutu benih. Akibatnya produktivitas usahatani padi di wilayah sasaran semakin menurun. Tujuan yang ingin dicapai adalah terjadi transfer teknologi tepat guna sehingga pengetahuan dan keterampilan petani tentang agribisnis dan pengelolaan hama terpadu (PHT) pada budidaya tanaman padi beras merah meningkat. Kegiatan dilaksanakan di Desa Kateng Kec. Praya Barat Kab. Lombok Tengah dari bulan Januari sampai dengan Juli 2020. Metode kegiatan yang dilaksanakan adalah Program Tindak Partisipatif (Participatori Action Program). Pendekatannya adalah dari bawah dan dari atas (Bottom-up and top down approach) dengan penekanan pada tingkat pengetahuan, keterampilan dan kearifan lokal para petani mitra (Hutwan et al., 2016). Mekanisme pelaksanan melalui beberapa tahap yaitu penyuluhan, penetapan petani sasaran sebagai mitra, pendampingan dan monitoring serta evaluasi program. Hasil kegiatan menunjukkan bahwa pengetahuan dan keterampilan petani tentang agribisnis dan PHT pada budidaya tanaman padi beras merah meningkat. Hal ini terlihat dari antusiasme petani sasaran mengikuti kegiatan penyuluhan dan pendampingan, serta penerapan teknologi tepat guna antara lain pengolahan tanah, penggunaan benih unggul, pupuk organik dan PHT pada budidaya tanaman padi. Teknologi tepat guna yang diintroduksikan menyebabkan pertumbuhan dan hasil padi beras merah lebih baik, intensitas serangan hama wereng menurun, sehingga memberikan hasil dan keuntungan yang lebih banyak dibandingkan dengan hasil budidaya manual
Modern possibilities of interventional radiology in the elimination of percutaneous nephrolithiasis surgery hemorrhagic complications
Authors: Suleymanov S. I. , Kadyrov Z. A. , Ramishvili V. Sh. , Chuvarayan G. A. , Musokhranov V. V. , Babkin A. S. 
Published: September 2021

Рurpose. To increase the treatment eff ectiveness of patients with various forms of nephrolithiasis based on the development and integration of interdisciplinary approaches to the choice of surgical access. Materials and methods. The study was based on clinical and laboratory data and the results of surgical treatment of 133 patients with various forms of urolithiasis. Results. The analysis of complications of percutaneous surgery is shown by the example of 133 patients with various forms of nephrolithiasis, who underwent PCNL (percutaneous nephrolithotomy). The inclusion of highly informative methods of visualization of urinary stones, multispiral computed tomography with 3D-visualization and densitometry namely in the algorithm of examination of patients with nephrolithiasis is justifi ed. The possibilities of interventional radiology in the elimination of hemorrhagic complications of percutaneous surgery of urolithiasis, including staghorn nephrolithiasis, are presented. Conclusion. The eff ectiveness of the creation of multidisciplinary surgical teams, including specialists in the fi eld of interventional radiology, for the interpretation of diagnostic results, as well as the prevention and elimination of intra- and postoperative hemorrhagic complications, is proven.
Psychological Impact and their Associated Factors of COVID-19 Pandemic among Nurses of a Metropolitan City of Central Nepal
Authors: Lamichhane Rama Kumari , Dhakal Bijaya , Thapa Asha , Sapkota Kalyan 
Published: September 2021

Introduction: COVID-19 poses a great challenge to the global health system. The nurses worked in COVID ward and fever clinic act as gatekeepers to the health care system in the public health response to COVID-19 epidemic. The consequences of lockdown, quarantine of COVID-19 pandemic has not only caused physical sufferings but also affected the mental health of the nurses around the globe. This study aimed to assess psychological impact and associated factors of COVID 19 pandemic among nurses working in different level of hospital at Bharatpur Municipality Chitwan, Nepal.
Methods: A cross-sectional descriptive study was conducted among 150 nurses working in different hospitals of Bharatpur Municipality. Non-probability Purposive Sampling Technique was used and Data was collected via online survey using Google Form questionnaire. COVID-19 peritraumatic distress index (CPDI) questionnaire was used to find out psychological impact. Statistical analysis of data was done using SPSS version 20.
Results: Total of 150 nurses were involved in the study where 99.3% were female, 45.3% in the age group of 26-35 years, mean age 27.22±6.612 years, 87.2% bachelor in nursing. Mild to moderate peritraumatic distress was found in 47.33% and 16% of respondents found to have severe distress level. Chi-square test showed that respondents level of knowledge (p=0.003) and presence of chronic disease (p=0.007) was statistically significant with level of distress.
Conclusions: Majority of the nurses had some form of psychological distress. Study highlights the need for counseling for distress and mental health during COVID-19 pandemic. A focus on improving mental wellbeing of nurses should be immediately initiated.
Fractures in patients with chronic kidney disease
Authors: Dudar S. L. 
Published: September 2021

Abstract. Despite rapid progress in improving dialysis technology in recent years, the mortality of patients treated with renal replacement therapy remains quite high. Mineral and bone disease is omnipresent in patients with chronic kidney disease (CKD) and leads to a diverse range of clinical manifestations, including bone pain and fractures. Mineral bone disorders (MBD), as well as changes in bone structure, develop at the beginning of CKD. Osteoporosis can progress according to declining of the glomerular filtration rate and contribute to the deterioration of bone strength resulted in a high risk of fracture. In CKD patients, the most common are hip fractures, femur, humerus, compression fractures of the vertebrae and pelvic fractures. CKD-MBD is characterized by disorders of calcium, phosphate, parathyroid hormone and/or vitamin D metabolism, as well as, bone regeneration, mineralization, volume, linear growth and strength violation, calcification of blood vessels, or other soft tissues. Medications that correct systemic mineral metabolism can improve bone histology in patients with CKD. However, clinical and biochemical targets used in clinical practice remain controversial, resulting in an undermanagement of bone fragility. The clarifying of the appropriateness of medicines that act directly on the bone or affect the mineral and hormonal metabolism could be a promising strategy to prevent pathological fractures due to fragility among CKD patients.
Gotovnost' sovremennykh roditelei k effektivnoi realizatsii ikh sotsial'noi roli "roditel'" (na primere izucheniia ottsov vospitannikov DOO)
Authors: Serebriakova Tatiana Aleksandrovna , Dvoriantseva Svetlana Vladimirovna , Shibalkina Svetlana Iur'evna , Anisimova Elena Aleksandrovna , Rechinskaia Elena Aleksandrovna 
Published: September 2021

The article reflects the results of experimental testing of the monitoring program, focused on studying the specifics of the manifestation of modern fathers' readiness to effectively implement their most important social role – «parent». Based on the results of research by scientists in the field of parenting (research by V.V. Abramenkova, A.I. Antonov, V.V. Boyko, V.I.Brutman, A.I. Zakharova, S.Yu. Meshcheryakova, R.V. Ovcharova, V.A.Petrovsky, N.Yu. Sinyagina, G.G. Filippova, A.G. Kharcheva; D. Bassin, E. Galinsky, M. Honey, M. Kaplan, etc.) and an experimental monitoring program was implemented, aimed at a detailed study of the readiness of the fathers of our pupils for responsible fatherhood. Having summarized the data obtained by us as a result of the monitoring program, we conclude that only a quarter of dads are responsible for the implementation of the role of «parent». Most fathers need help for raising their children. We define the development and subsequent implementation of the program of psychological and pedagogical support for dads in the upbringing of their children in the practice of preschool educational institutions as the target guidelines for our future activities.
Novel Reviews
Authors: Toivanen Anna-Leena , Taylor Joanna E. 
Published: September 2021

Michèle Rakotoson, Elle, au printemps (Saint-Maur: Sépia, 1996), 122 pp.Kathleen Jamie, Surfacing (UK: Sort of Books, 2019), 240 pp., £7.99. Kathleen Jamie (ed.), Antlers of Water: Writing on the Nature and Environment of Scotland (Edinburgh: Canongate Books, 2020), 232pp., £20.
Book Reviews
Authors: Dinter Sandra , Tsai Weipin , Caset Freke 
Published: September 2021

Kerri Andrews, Wanderers: A History of Women Walking (London: Reaktion Books, 2020), 303 pp., £14.99Nanny Kim, Mountain Rivers, Mountain Roads: Transport in Southwest China, 1700–1850 (Leiden; Boston: Brill, 2019), xxvi, 621 pp, €149/$179Karen Chapple and Anastasia Loukaitou-Sideris, Transit-Oriented Displacement or Community Dividends? (Cambridge, MA: Th e MIT Press, 2019), 347 pp., 67 black-and-white illustrations, $40.00
Analisis Reaksi Investor Sebelum Pengumuman dan Setelah Pencabutan Suspensi Saham
Authors: Rangkuti Hamdani Arifulsyah , Ali Fifitri , Bhayangkara Abdi 
Published: September 2021

AbstractThe purpose of this research is to analyze descriptively qualitatively to test whether the abnormal return, trading Volume activity and Bid-Aks spread have a positive or negative value before the announcement suspension and after unsuspension. After that, testing with a different test (paired sample t-test). This research is an event study, using an estimated period of 5 days before the announcement of the suspension, and 5 days after the withdrawal of the suspension (unsuspension), within the period of observation in the year 2019. The sample in this study was 75 companies that announced the stock suspension. as well as announcing stock unsuspension in 2019. The results of this study show that the average abnormal return, trading Volume activity and Bid-Aks spread show a positive value both before the announcement of the stock suspension and after the stock unsuspension. Meanwhile, for the different test results (paired sample t-test), there is a significant difference before the announcement of stock suspension and after stock unsuspension for the abnormal return variable and the Bid-Aks spread, while the trading Volume activity must be excluded from the study because SPSS did not include it so the exclude variable category. Abstrak Riset ini bertujuan menganalisis secara deskriptif kualitatif apakah abnormal return, Trading Volume activity dan Bid-Aks spread memiliki nilai positif atau negatif pada saat sebelum pengumunan dan setelah pencabutan suspensi saham. Pengujian berikutnya adalah dengan melakukan uji beda berpasangan (paired sample t-test). Periode penelitian ini adalah 5 hari sebelum pengumuman suspensi saham, dan 5 hari setelah penarikan suspensi saham (unsuspensi), dalam rentang waktu pengamatan dari selama tahun 2019. Sebanyak 75 perusahaan yang mengumumkan suspensi dan unsuspensi saham selama tahun 2019. Hasil penelitian ini menunjukkan bahwa rata-rata Abnormal Return, Trading Volume Activity dan Bid-Aks Spread menunjukkan nilai yang positif baik sebelum pengumuman suspensi saham, maupun setelah unsuspensi saham. Sementara untuk hasil uji bedanya, beda yang cukup nyata sebelum pengumuman suspensi saham dan setelah unsuspensi saham untuk variabel Abnormal Return dan Bid-Aks Spread, sementara untuk variabel Trading Volume Activity dikeluarkan dari penelitian karena di SPSS termasuk kedalam kategori exclude variable.
Psychotic Features as Initial Presentation of Intracranial Epidermoid of Suprasellar Origin
Authors: Jain Nidhi , Isha Patidar 
Published: September 2021

Intracranial epidermoids are rare congenital lesions which account for around 1% of all intracranial tumors. They present most commonly in cerebello-pontine angle followed by suprasellar region, along with different intracranial areas. The most common presentation includes headache, cranial nerve deficiets, seizures, raised intracranial pressure. It is extremely uncommon for epidermoid tumors to present with psychiatric symptoms. We present a case of 38 year old female with history of psychosis for 2 years with personality change, disorganised behavior and delusions. An episode of increased sedation and semi-consciousness led to neuroimaging which revealed a large epidermoid tumor of suprasellar region and interpeduncular region. Surgical resection of the epidermoid was done and patient was maintained on drug treatment.
Keywords: Epidermoid tumour, Psychosis