bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUMAN FACTORS AFFECTING DIGITAL SECURITY
Authors: Dutta Avijit 
Published: February 2021

World is getting digital at an exponential rate. Commonplace activities are accomplished increasingly over digital platform to bring in requirement of digital security in place of only physical security. Security (physical or digital or both) is essential for safe storage, retrieval and exchange of physical or digital data and documents. As data/information/knowledge leading to wisdom are increasingly getting endowed with economic values the risk for such assets being pilfered are also increasing. This requires methods for their security being augmented continuously. Society from past to present days are putting their best efforts in this end. Generally, it is achieved through hiding the message from predator’s greedy glare and ensuring its temper-free safe passage to desired destination with deception in various forms. Associated processes are complex and during initial days were executed with various forms of arts and riddles. Over years technology driven solutions were evolved to ensure today’s digital security requirements [7],[8].
Motivation/Background: Presently occurrence of digital security disasters is not few and far between, instead they are alarmingly many, though technology for digital security is improving by leaps and bounds. More often than not, in case of a digital catastrophe dominant foot prints of human involvement are found along with technical snags. It may be noted that technical failure can be assessed and rectified in an organized way though causes of human involvement are difficult to judge as they are much abstract in nature and difficult to measure. Thus, this effort to explore human role in digital disaster.
Method: In present text traditional to most current practices of securing data storage, retrieval and disbursal are touched upon. During earlier days data hiding technique from predator’s glare had been more of an artistic than scientific form. Over years mathematical and statistical approach were induced to make the system more robust though secrets are exposed even today at an alarming rate and at times by their own creators to usher security disasters. As the discussion progressed results from secondary sources are presented to make a broad statement on current scenario. Finally, indicators like NCSI (National Cyber Security Index) and DDL (Digital Development Level) from NCSI site and HDI (Human Development Index) from Human Development Report of 2019, produced by UNDP, are considered for analysis to have better insight. These figures are available on public domain for general referral [24],[25].
Results: It has been observed that beyond technical complications, human factors play a dominant role in ensuring security.
Pemulihan Wisata Pantai Telawas Era New Normal dengan Menerapkan Protokol Destinasi di Desa Mekar Sari Kecamatan Praya Barat
Authors: Hafiddin Lalu Iqra , Kurniawan Lalu Rizki Rensa , Assauri Lalu Sofyan , Ammar Khaeril , Pujiana Irpan Manik , Nuriadi Nuriadi 
Published: February 2021

Pariwisata merupakan sektor industry yang penting untuk menigkatkan pendapatan masyarakat dan Negara. Kompleksitas dari Pandemi Covid – 19 telah merubah pola interaksi social tak terkecuali sektor pariwisata. Perencanaan dan pemulihan dalam sektor pariwisata melalui penerapan protocol kesehatan mulai dari edukasi, penggunaan masker, menyediakan hand sanitaizer di titik keramiaan destinasi, dan pemasangan pamphlet/baner untuk mematuhi protocol kesehatan. Tujuan dari program ini untuk memulihkan kembali destinasi wisata yang ada di Desa Mekar Sari Kecamatan Praya Barat, Kabupaten Lombok Tengah guna mengembalikan pendapatan masyarakat yang sempat turun drastis akibat pandemic Covid – 19 dengan bersandar pada protocol kesehatan. Program ini menggunakan penelitian kualitatif dengan pendekatan deskriptif. Kemudian pengolahan data di analisis yang disajikan dalam bentuk kesimpulan. Hasil dari program ini berupa panduan pemulihan pariwisata yang berbasis pada protocol kesehatan yang akan disebut sebagai protocol destinasi wisata.
Sebaran tingkat kemiskinan dan tingkat akses air bersih di Sumatera Selatan
Authors: Yesi Desri , Juairiyah Oktaf 
Published: February 2021

The poverty level and the level of access for cleaning water are two interesting variables to analyze. One type of feasible analysis was used scatter diagram. South Sumatra Province with its 17 municipalities has different characteristics in terms of poverty levels and access to clean water for the people. Overall, using the scatter diagram, in 2018 the areas with low poverty levels however high levels of access to clean water (Quadrant I) were Lahat and Penukal Abab Lematang Ilir Regency. The regions with low levels of access to clean water and low levels of poverty (Quadrant II) are Empat Lawang, Banyuasin, Ogan Komering Ulu Selatan and Prabumulih. The areas with high levels of access to clean water and high poverty (Quadrant III) are Musi Rawas Utara, Musi Banyuasin, Ogan Komering Ilir, Musi Rawas and Ogan Ilir Regency. The areas with low levels of access to clean water and high poverty (Quadran IV) are Lahat and Penukal Abab Lematang Ilir regency.
Kesesuaian dan daya dukung lingkungan untuk pengembangan ekowisata di kawasan hutan Gunung Mareje Utara Kabupaten Lombok Tengah
Authors: Nawari Nawari , Isjoni Isjoni , Zulkarnaini Zulkarnaini 
Published: February 2021

North Mareje Mountain Forest Area (NMMFA) is one of important areas for ecotourism development in Lombok Island. Currently integrated ecotourism management plan (IEMP) is not available for this area, it has caused land degradation and natural disasters. To support sustainable IEMP establishment, this study was conducted with objectives to analyze land suitability and assessing the environmental carrying capacity of ecotourism development. The study conducted in NMMFA, Serage Village, Central Lombok, NTB during January - March 2020. The data used in this study include attractiveness, landscape naturalness, bio-geophysical limiting factors, accessibility, optimal space requirements and length time of tourist activities. Secondary data compiled from various sources and primary data collected by field observations and interviews. Land suitability analysis used weighted linear combination (WLC), environment carrying capacity analyzed by Douglas Method (Zacarias et al., 2011) and the evaluation conducted by t-test. Based on the analysis, explained that land suitable area for ecotourism in NMMFA is 1.235,2 Ha (75,8% of total area). Effective carrying capacity (ECC) is 32.729 visitors/day. The important indicators contributed to land suitability include soil conservation, tree diversity, visibility and natural attractiveness. T-test analysis shows that the actual landuse for ecotourism smaller than potential area, the average number of tourist visits in the area also smaller than the ECC. It can be concluded if the current land utilization have been meet with land suitability and environmental carrying capacity.
Job Satisfaction among Nurses Working in a Tertiary Level Government Hospital
Authors: Singh Ajanta , Chakradhar Roshi , Joshi Nibaran 
Published: February 2021

Introduction: Job satisfaction refers to the employees having a feeling of job stability, career growth and a comfortable work life balance which implies that the employee is having satisfaction at job and the individual’s expectations are met. Job satisfaction is one of the most important factors that determine efficiency and productivity of human resources. It is vital to increase nurse’s job satisfaction to improve patients care quality and ensure adequate nursing workforce which helps in the development of effective strategies to address the nursing shortage and increase the quality of patient care. The objective of this study was to assess the level of job satisfaction among nurses working in the government hospital.
Methods: A descriptive cross-sectional design was adopted. All the nursing staffs working in Kanti Children’s Hospital, Kathmandu, Nepal were the study population and the total sample size was 81, selected using stratified random sampling techniques from different wards. The information was collected by using self-administered structured questionnaire. Level of job satisfaction was assessed by using 5point Likert Scale. The collected data were entered into SPSS version 16 and were analysed using descriptive and inferential statistics.
Results: The study findings showed that almost half (46.9%) of the respondents were satisfied with their current job. The satisfaction mean score obtained by work itself and nursing practice was (23.35 + 4.25) followed by advancement opportunity with mean value (20.44 + 4.97). Similarly, the satisfaction score obtained for recognition and reward (6.80 + 2.62) followed by participation in decision making with mean value (9.45 + 2.24). There was a statistical association between the level of job satisfaction and ethnicity (p = 0.41), marital status (p = 0.005), professional qualification (p = 0.001) and work experience (p = 0.002) of the respondents.
Conclusions: Based on the findings it is concluded that nearly half of the nurses were satisfied with their job. The most satisfying factor is the work itself whereas the least satisfying factor is the recognition and reward given to them followed by participation in decision making.
The Clinical Profile of Idiopathic Optic Neuritis at the Ophthalmology OPD of Tertiary Centre of Army Hospital, Nepal
Authors: Rajkarnikar Sagar , Gurung Anu , Pant Shambhu Nath 
Published: February 2021

Introduction: Inflammation of the optic nerve is a common cause of visual loss due to optic nerve pathology. This study was conducted to report the clinical features, demographic pattern and response to pulse steroid therapy in patients with idiopathic optic neuritis in a tertiary care teaching institute in Kathmandu, Nepal.
Methods: The hospital data of patients with idiopathic optic neuritis admitted to the Department of Ophthalmology of Shree Birendra Hospital, Chhauni, Kathmandu, Nepal between Jan 2015 to Dec 2018 were retrospectively analysed. The parameters studied were demographic pattern, clinical features, and visual acuity.
Results: Eighteen eyes of 15 patients were found to have optic neuritis (papillits in eight and retrobulbar optic neuritis in 10 eyes). The male to female ratio was 1.4:1. The mean age of the patients was 38.07 ± 11.37 years (95% CI = 31.77- 42.37). The most common modes of presentation were loss of visual acuity, painful ocular movement and colour vision defect. One patient had features suggestive of multiple sclerosis. Response to pulse methylprednisolone therapy was good in most (16 eyes) of the cases except for the patients having recurrent episode and started oral steroid elsewhere before presenting to our hospital.
Conclusions: Response to pulse methylprednisolone therapy was good in patients with initial visual acuity of at least perception of light. Demographic and clinical features of our patients were different from those reported from the western world.
POLA KOMUNIKASI MELALUI MEDIA WHATSAPP SEBAGAI SUMBER INFORMASI KARYAWAN BAGIAN OPERASIONAL DI PT. ARTISAN WAHYU
Authors: Olivia Helen 
Published: February 2021

Abstrak - Penelitian ini membahas tentang bagaimana pola komunikasi dan cara menerima dan menolak pesan yang diterima oleh karyawan PT Artisan Wahyu melalui media Whatsapp. Tujuan dari penelitian ini adalah untuk mengetahui pola komunikasi dan cara penerimaan dan penolakan yang diterima oleh karyawan PT Artisan Wahyu melalui media Whatsapp. Penelitian ini menggunakan teori komunikasi otoritas. Paradigma yang digunakan adalah konstruktivisme dengan pendekatan penelitian kualitatif. Metode yang digunakan adalah studi kasus. Subjek penelitian dalam penelitian ini terdiri dari informan kunci dan informan. Teknik pengumpulan data menggunakan wawancara dan observasi. Hasil penelitian ini menunjukkan bahwa pola komunikasi formal berupa komunikasi top down. Karyawan selalu mengikuti dan mengerjakan arahan yang diberikan oleh pimpinan, karena mereka percaya bahwa pesan yang disampaikan tidak bertentangan dengan tujuan organisasi (untuk kepentingan perusahaan). .Kata Kunci: Pola Komunikasi, Karyawan, media Whatsapp
Yield and Economic Response of Peanut (Arachis hypogaea L.) Cultivars to Prohexadione Calcium in Large-Plot Trials in Georgia
Authors: Monfort W.S. , Tubbs R.S. , Cresswell B.L. , Jordan E.L. , Smith N.B. , Luo X. 
Published: February 2021

ABSTRACT
Prohexadione calcium, a plant growth regulator, has been used on virginia market type peanut cultivars for many years to manage excessive vine growth and improve digging efficiency. Prohexadione calcium has not been widely used on runner market type cultivars due to their slower growth habit and sporadic yield response at the labeled rate until recent research showed lower use rates of prohexadione calcium provided similar vine control and enhanced yield response. Large plot experiments were conducted in Colquitt county at the Darrell Williams Research Farm on the Sun Belt Ag Expo to quantify yield and market grade quality and economics of using prohexadione calcium at 105 g a.i./ha on six runner type cultivars. Prohexadione calcium was applied twice during the growing season. The first application was made when 50% or greater of lateral vines from adjacent rows were touching. A second application of each treatment was applied 14d after the first application. The runner type cultivars were Georgia-06G, Georgia-12Y, Georgia-13M, Georgia-14N, TUFRunnerTM-297, and TUFRunnerTM-511. Similar large-plot experiments were conducted on farms in Baker and Early counties evaluating yield and economic response of prohexadione calcium on Georgia-06G. A non-treated control was used in all experiments. Prohexadione calcium increased pod yield in all experiments ranging from 450 to 650 kg/ha compared to the non-treated control with response similar across cultivars. Prohexadione calcium reduced the dollar value per metric ton (DVMT) as a result of lowering total sound mature kernel (%TSMK) percentages up to 3 points. The higher yields obtained for the prohexadione calcium-treated peanut provided higher gross dollar value return/ha (GDR) in all experiments and higher gross dollar value return/ha above treatment cost (GDRAT) in the on-farm trials. Therefore, prohexadione calcium at 105 g/ha applied twice on runner market type peanut is warranted to improve yield and financial return when excessive vine growth is a concern.
Preclinical efficacy of ribavirin in SHH and group 3 medulloblastoma
Authors: Huq Sakibul , Kannapadi Nivedha V. , Casaos Joshua , Lott Tarik , Felder Raphael , Serra Riccardo , Gorelick Noah L. , Ruiz-Cardozo Miguel A. , Ding Andy S. , Cecia Arba , Medikonda Ravi , Ehresman Jeff , Brem Henry , Skuli Nicolas , Tyler Betty M. 
Published: February 2021

OBJECTIVE
Medulloblastoma, the most common pediatric brain malignancy, has Sonic Hedgehog (SHH) and group 3 (Myc driven) subtypes that are associated with the activity of eukaryotic initiation factor 4E (eIF4E), a critical mediator of translation, and enhancer of zeste homolog 2 (EZH2), a histone methyltransferase and master regulator of transcription. Recent drug repurposing efforts in multiple solid and hematologic malignancies have demonstrated that eIF4E and EZH2 are both pharmacologically inhibited by the FDA-approved antiviral drug ribavirin. Given the molecular overlap between medulloblastoma biology and known ribavirin activity, the authors investigated the preclinical efficacy of repurposing ribavirin as a targeted therapeutic in cell and animal models of medulloblastoma.

METHODS
Multiple in vitro assays were performed using human ONS-76 (a primitive SHH model) and D425 (an aggressive group 3 model) cells. The impacts of ribavirin on cellular growth, death, migration, and invasion were quantified using proliferation and Cell Counting Kit-8 (CCK-8) assays, flow cytometry with annexin V (AnnV) staining, scratch wound assays, and Matrigel invasion chambers, respectively. Survival following daily ribavirin treatment (100 mg/kg) was assessed in vivo in immunodeficient mice intracranially implanted with D425 cells.

RESULTS
Compared to controls, ribavirin treatment led to a significant reduction in medulloblastoma cell growth (ONS-76 proliferation assay, p = 0.0001; D425 CCK-8 assay, p < 0.0001) and a significant increase in cell death (flow cytometry for AnnV, ONS-76, p = 0.0010; D425, p = 0.0284). In ONS-76 cells, compared to controls, ribavirin significantly decreased cell migration and invasion (Matrigel invasion chamber assay, p = 0.0012). In vivo, ribavirin significantly extended survival in an aggressive group 3 medulloblastoma mouse model compared to vehicle-treated controls (p = 0.0004).

CONCLUSIONS
The authors demonstrate that ribavirin, a clinically used drug known to inhibit eIF4E and EZH2, has significant antitumor effects in multiple preclinical models of medulloblastoma, including an aggressive group 3 animal model. Ribavirin may represent a promising targeted therapeutic in medulloblastoma.
Diffusion tensor imaging in children following prenatal myelomeningocele repair and its predictive value for the need and timing of subsequent CSF diversion surgery for hydrocephalus
Authors: Yuan Weihong , Stevenson Charles B. , Altaye Mekibib , Jones Blaise V. , Leach James , Lovha Mykhailo , Rennert Noa , Mangano Francesco T. 
Published: February 2021

OBJECTIVE
The aim of this study was to investigate diffusion tensor imaging (DTI), an objective and noninvasive neuroimaging technique, for its potential as an imaging biomarker to predict the need and timing of CSF diversion surgery in patients after prenatal myelomeningocele (MMC) repair.

METHODS
This was a retrospective analysis of data based on 35 pediatric patients after prenatal MMC repair (gestational age at birth 32.68 ± 3.42 weeks, range 24–38 weeks; 15 females and 20 males). A logistic regression analysis was used to classify patients to determine the need for CSF diversion surgery. The model performance was compared between using the frontooccipital horn ratio (FOHR) alone and using the FOHR combined with DTI values (the genu of the corpus callosum [gCC] and the posterior limb of the internal capsule [PLIC]). For patients who needed to be treated surgically, timing of the procedure was used as the clinical outcome to test the predictive value of DTI acquired prior to surgery based on a linear regression analysis.

RESULTS
Significantly lower fractional anisotropy (FA) values in the gCC (p = 0.014) and PLIC (p = 0.037) and higher mean diffusivity (MD) values in the gCC (p = 0.013) were found in patients who required CSF diversion surgery compared with those who did not require surgery (all p values adjusted for age). Based on the logistic regression analysis, the FOHR alone showed an accuracy of performance of 0.69 and area under the receiver operating characteristic curve (AUC) of 0.60. The performance of the model was higher when DTI measures were used in the logistic regression model (accuracy = 0.77, AUC = 0.84 for using DTI values in gCC; accuracy = 0.75, AUC = 0.84 for using DTI values in PLIC). Combining the DTI values of the gCC or PLIC and FOHR did not improve the model performance when compared with using the DTI values alone. In patients who needed CSF diversion surgery, significant correlation was found between DTI values in the gCC and the time interval between imaging and surgery (FA: ρ = 0.625, p = 0.022; MD: ρ = −0.6830, p = 0.010; both adjusted for age and FOHR).

CONCLUSIONS
The authors’ data demonstrated that DTI could potentially serve as an objective biomarker differentiating patients after prenatal MMC repair regarding those who may require surgery for MMC-associated hydrocephalus. The predictive value for the need and timing of CSF diversion surgery is highly clinically relevant for improving and optimizing decision-making for the treatment of hydrocephalus in this patient population.
DEVELOPMENT OF HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY METHOD FOR QUANTITATION OF ?-SITOSTEROL IN NORMACID SYRUP: A POLY HERBAL FORMULATION
Authors: H Shah Kinjal , Rajeshree Makwana 
Published: February 2021

Normacid syrup consisiting of 17 ingredients, used in the treatment of hyperacidity and gastritis. ?- Sitosterol is one of the phytoconstituent present in Normacid syrup- a poly herbal formulation. In the present study an attempt has been made to develop a HPTLC method for quantitative estimation of ?- Sitosterol in dried plant parts used in formulations. This HPTLC method was found to be reproducible, accurate, precise and detect ?- Sitosterol at nanogram level. The developed HPTLC method would be an important tool in the quality control method of poly herbal formulation.
Keywords: HPTLC, Polyherbal, ?- Sitosterol, Gastritis
STRUKTUR KOMUNITAS VEGETASI MANGROVE DI PESISIR UTARA PULAU MENDANAU DAN PULAU BATU DINDING, KECAMATAN SELAT NASIK KABUPATEN BELITUNG
Authors: Akhrianti Irma , Franto Franto , Nurtjahya Eddy , Syari Indra Ambalika 
Published: February 2021

Mendanau Island and Batu Dinding Island are part of small island groups that have a high diversity and density of mangroves. Based on administratively, Mendanau Island is located in the coastal area of Simpang Pesak District, Belitung Regency, which consist of one large island (Mendanau Island) and 1 small island (Batu Dinding Island). The lack of data about potential, diversity, and community structure of mangroves on the north coast of Mendanau Island and Batu Dinding Island, therefore this research is needed as a database for planning, sustainability management of mangroves at the coastal area and small island. The data of mangrove vegetation was taken by purposive sampling method, with using line transect plot (LTP). Ilustration of sampling design is each line transect have 3 plot / kuadratic transect sized 10 m x 10 m (capling), 5 m x 5m (sapling), 1m x 1 m (seedling). The result showed that there are 12 (twelve) mangrove species were found: jenis S. alba, R. apiculata, R. stylosa, R. mucronata, B. gymnorhiza, X. granatum, L. littorea. S. hydrophyllacea, S. taccada, H. tiliaceus, Pandanus, dan I. pes-caprae. Mangrove community structure and mangrove condition on the North Coast of Mendanau Island, at several observation stations, was damaged (poor conditions), while the status of the mangrove conditions on Pulau Batu Dinding was still relatively good
Aconselhamento oncogenético como tecnologia assistencial em enfermagem oncológica: uma revisão integrativa
Authors: Almeida Jamilie Ferrarez , Souza Sônia Regina de , Sales Lívia de Alcântara , Albuquerque Ana Carolina Gonçalves Duarte de , Albuquerque Ieda Lessa de Souza , Campo Lívia Lírio 
Published: February 2021

O aconselhamento genético é a assistência prévia, a interpretação de achados e estimativas de riscos genéticos para pessoas clinicamente saudáveis, com familiares que apresentem diagnóstico e doença rara documentada. O objetivo deste estudo é identificar, a partir da produção científica na área de enfermagem, a participação do enfermeiro no aconselhamento oncogenético, apontando suas práticas e desafios. Para atingir tal objetivo, foi utilizado o método de revisão integrativa da literatura. Foram encontrados na busca inicial um total de 1007 artigos. Ao aplicar os critérios de inclusão e exclusão, selecionaram-se 5 artigos para análise, que após examinados foram categorizados com baixo nível de evidência. A partir dos resultados obtidos, foi possível observar a escassez de conteúdo qualificado e conhecimento do assunto por parte dos profissionais da área. O enfermeiro está em um posicionamento ideal no serviço de saúde, ter uma base do conhecimento sobre a função do profissional na área, prepara a força de trabalho da enfermagem para oferecer cuidados hábeis com o foco no Aconselhamento Oncogenético.