bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physiological Impact of Afterload Reduction on Cardiac Mechanics and Coronary Hemodynamics Following Isosorbide Dinitrate Administration in Ischemic Heart Disease
Authors: Patterson Tiffany , Rivolo Simone , Burkhoff Daniel , Schreuder Jan , Briceno Natalia , Allen Christopher , Williams Rupert , Arri Satpal , Asrress Kaleab N. , Joseph Jubin , McConkey Hannah Z. R. , Ellis Howard , Pavlidis Antonis , Clapp Brian , Perera Divaka , Lee Jack , Marber Michael S. , Redwood Simon R. 
Published: March 2021

Abstract
Understanding the cardiac-coronary interaction is fundamental to developing treatment strategies for ischemic heart disease. We sought to examine the impact of afterload reduction following isosorbide dinitrate (ISDN) administration on LV properties and coronary hemodynamics to further our understanding of the cardiac-coronary interaction. Novel methodology enabled real-time simultaneous acquisition and analysis of coronary and LV hemodynamics in vivo using coronary pressure-flow wires (used to derive coronary wave energies) and LV pressure-volume loop assessment. ISDN administration resulted in afterload reduction, reduced myocardial demand, and increased mechanical efficiency (all P<0.01). Correlations were demonstrated between the forward compression wave (FCW) and arterial elastance (r=0.6) following ISDN. In the presence of minimal microvascular resistance, coronary blood flow velocity exhibited an inverse relationship with LV elastance. In summary this study demonstrated a reduction in myocardial demand with ISDN, an inverse relationship between coronary blood flow velocity and LV contraction-relaxation and a direct correlation between FCW and arterial elastance.

Graphical abstract
The pressure volume-loop and corresponding parameters b The pressure volume loop before (solid line) and after (broken line) Isosorbide dintrate
Choosing how to discriminate: navigating ethical trade-offs in fair algorithmic design for the insurance sector
Authors: Loi Michele , Christen Markus 
Published: March 2021

AbstractHere, we provide an ethical analysis of discrimination in private insurance to guide the application of non-discriminatory algorithms for risk prediction in the insurance context. This addresses the need for ethical guidance of data-science experts, business managers, and regulators, proposing a framework of moral reasoning behind the choice of fairness goals for prediction-based decisions in the insurance domain. The reference to private insurance as a business practice is essential in our approach, because the consequences of discrimination and predictive inaccuracy in underwriting are different from those of using predictive algorithms in other sectors (e.g., medical diagnosis, sentencing). Here we focus on the trade-off in the extent to which one can pursue indirect non-discrimination versus predictive accuracy. The moral assessment of this trade-off is related to the context of application—to the consequences of inaccurate risk predictions in the insurance domain.
Addressing physical health in mental illness: the urgent need to translate evidence-based interventions into routine clinical practice
Authors: O’Donoghue B. 
Published: March 2021

AbstractPeople affected by severe mental health disorders have a greatly reduced life expectancy compared to their non-affected peers. Cardiovascular disease is the main contributor to this early mortality, caused by higher rates of smoking, physical inactivity, unhealthy diet, sleep disturbance, excessive alcohol use or substance abuse and medication side effects. Therefore, we need to take a preventative approach and translate effective interventions for physical health into routine clinical practice. These interventions should be delivered across all stages of mental health disorders and could also have the added benefit of leading to improvements in mental health. Furthermore, we need to advocate to ensure that people affected by severe mental health disorders receive the appropriate medical assessments and treatments when indicated. This themed issue highlights that physical health is now an urgent priority for funding and development in mental health services. The widespread implementation of evidence-based interventions into routine clinical practice is an essential need for consideration by clinicians and policymakers.
Development and validation of the preschool peer bullying scale-teacher form
Authors: Besnili Zeynep Nur , Tanrikulu Ibrahim 
Published: March 2021

AbstractBased on labelling theory, the Preschool Peer Bullying Scale-Teacher Form (PPBS-Teacher Form) was developed, and its validity and reliability were tested in this current study. There were 279 Turkish preschool teachers (96% females) in the preliminary study sample. Exploratory factor analyses were conducted with the data from the preliminary study sample, revealing 14 items with two factors, named as physical-relational bullying and verbal bullying. There were 247 Turkish preschool teachers (97% females) in the cross-validation study sample. Confirmatory factor analyses were carried out with the data from the cross-validation study sample, revealing adequate fit to the data. The internal consistency coefficients were high for the two study samples. Hence, the PPBS-Teacher Form is a valid and reliable measurement instrument to assess preschool peer bullying without labelling students as bullies or victims. The PPBS-Teacher Form aims to contribute to the extant research on early childhood bullying by attracting attention to the risks of labelling preschool students as bullies or victims. Practical implications are discussed for school counsellors and psychologists, parents and researchers.
Changes in food intake from 1999 to 2012 among Mexican children and women
Authors: Reyes-Garcia Alan , Stern Dalia , Rivera-Dommarco Juan , Batis Carolina 
Published: March 2021

AbstractPrevious studies have shown that intake of sugary drinks in Mexico has increased, while intake of whole milk has decreased. Yet, in-depth analyses of the changes in solid foods, overall and in specific generations and urban/rural subpopulation, are scarce. We aimed to analyse changes in solid foods intake in Mexican children, adolescent girls and adult women through a single 24-h dietary recall from the Mexican Nutrition Survey 1999 (n 5627) and 2012 (n 6712). Foods were classified into twenty-two healthy and unhealthy food groups without considering beverages. We estimated the crude and adjusted change in the energy contribution of solid foods by age group and birth cohort and tested if the changes differed by urban/rural area. The contribution of fruits, vegetables and unsweetened dairy increased, while sweet bread from bakery decreased. However, the total contribution of healthy food groups (67–70 % kj in 1999) decreased −4·3 and −7·2 percentage points (pp) (P < 0·05) among children and adolescents, respectively, but only −1·7 pp (P > 0·05) among adult women. Likewise, those born in 1980–1984 changed little in comparison with those born in 1993–1997, and there were greater increases in unhealthy foods in urban compared with rural areas. In conclusion, from 1999 to 2012, there were negative changes in the intake of foods, specifically healthy foods, which mainly affected Mexican youth. These findings, along with previous reports on the increased intake of sugary drinks in the same population, that emphasise the need to reinforce strategies aimed at improving dietary intake of the Mexican population need to be reinforced.
Relationship between seaweeds consumption and hyperuricaemia in general adults: a Population-based study from the Tianjin Chronic Low-grade Systemic Inflammation and Health (TCLSIH) cohort study
Authors: Zhang Tingjing , Wang Yawen , Gu Yeqing , Meng Ge , Zhang Qing , Liu Li , Wu Hongmei , Zhang Shunming , Wang Xuena , Sun Shaomei , Wang Xing , Zhou Ming , Jiao Huanli , Jia Qiyu , Song Kun , Wu Yuntang , Wu Xiao-Hui , Niu Kaijun 
Published: March 2021

AbstractSeaweeds have numerous biologically active ingredients, such as polysaccharides, polyphenols and carotenoids, that are beneficial to human health. Although these benefits might be related to the synthesis, secretion or reabsorption of uric acid, no studies have explored the relationship between seaweeds consumption and hyperuricaemia (HUA) in the general population. The aim of this study was to investigate whether seaweeds consumption is related to HUA in a large-scale adult population. A cross-sectional study was conducted with 32 365 adults (17 328 men and 15 037 women) in Tianjin, People’s Republic of China. Frequency of seaweeds consumption was assessed by a validated self-administered FFQ. HUA was defined as serum uric acid levels >420 μmol/L in men and >350 μmol/L in women. The association between seaweeds consumption and HUA was assessed by multiple logistic regression analysis. Restricted cubic spline functions were used for non-linearity tests. The prevalence of HUA in men and women was 21·17 % and 5·93 %, respectively. After adjustments for potential confounding factors, the OR (95 % CI) for HUA across seaweed consumption (g/1000 kcal per d) were 1·00 (reference) for level 1, 0·91 (95 % CI 0·81, 1·02) for level 2; 0·90 (95 % CI 0·81, 1·01) for level 3; 0·86 (95 % CI 0·78, 0·97) for level 4 in men and 0·90 (95 % CI 0·73, 1·10) for level 2; 0·82 (95 % CI 0·67, 1·00) for level 3; 0·84 (95 % CI 0·68, 1·03) for level 4 in women, respectively. A negative correlation between seaweeds consumption and HUA in males but not in females was observed. Further studies are needed to explore the causal relationship.
The politics of the Hajj organisation in Senegal: security, legitimation and clientelism
Authors: Jourde Cédric , Brossier Marie , Gomez-Perez Muriel 
Published: March 2021

ABSTRACTThis article analyses how the state in Senegal has managed the hajj since the liberalisation era in the early 2000s. Although the essence of the hajj is religious, it is also deeply political and requires that the state manages complex relations with pilgrims, religious leaders, private travel agencies, politicians and Saudi authorities. This article argues that three inter-related imperatives structure the conduct of the Senegalese state: a security imperative, a legitimation imperative, and a clientelistic imperative. Security concerns lead the state to monitor and control pilgrims travelling to Mecca. Legitimation is seen in the collaborative relations with Sûfi orders and in the framing of the hajj organisation as a ‘public service’. Finally, given the magnitude of financial and symbolic resources attached to the hajj, clientelistic relations are constitutive of state officials’ actions. Overall, despite the post-2000 liberalisation of the hajj, the state has maintained its role as a gatekeeper, regulator and supervisor.
Unravelling the adoption of youth quotas in African hybrid regimes: evidence from Morocco
Authors: de Paredes Marta Garcia , Desrues Thierry 
Published: March 2021

ABSTRACTParliamentary youth quotas have been adopted by nine countries, mainly African autocracies. They have also attracted the attention of international organisations, which consider them indicators of democratic progress. Why were these quotas adopted? This article challenges the long-standing regime survival thesis by explaining quota adoption as the result of the convergent strategies of actors placed inside and outside the regime. It also provides new theoretical arguments that point to the transformation of representative linkages in hybrid regimes and shows how this is justified in the light of empirical evidence grounded on qualitative methodology and extensive fieldwork. By connecting the broader historical and socio-political context where youth quotas emerged – Africa – to the micro-level processes of quota adoption – based on the Moroccan case – this article provides a dynamic picture of how political representation is claimed and mobilised in contemporary Africa while shedding some light on the inclusive limits of quota policies.
Karl Barth's ontology of holy scripture revisited
Authors: Xu Ximian 
Published: March 2021

AbstractThis paper seeks to examine Barth's ontology of holy scripture by appropriating the latest nomenclatural analysis of Barth's usage of Wesen and Sein. Given the difference between the Wesen and the Sein of the Bible, and the claim that the Sein-in-becoming of the Bible is determined by its Wesen-in-act, it follows that for Barth the Bible is ontologically the Word of God in the sense of Wesen, which underlies the Bible's becoming the Word of God in the sense of Sein. In short, the Bible ontologically becomes the Word of God in the sense of Sein because the Bible is the Word of God in the sense of Wesen.
Between God and the world: a critical appraisal of the sophiology of Sergius Bulgakov
Authors: May Richard 
Published: March 2021

AbstractThe sophiology of Sergius Bulgakov has exerted a significant amount of influence over Anglophone theology over the last decade. Theological figures as significant as Rowan Williams, John Milbank and Paul Fiddes, to name but a few, have positively engaged with and utilised Bulgakov's sophiology within their own theological contributions. Thus, for many, Bulgakov's sophiology has proven to be a fecund source of theological inspiration, especially when articulating the relationship between God and the world. However, historically, Bulgakov's sophiology has been criticised by many Orthodox theologians, who argue that Bulgakov's proposals are theologically flawed and challenge traditional orthodox readings of Christian doctrine. Despite the controversy surrounding Bulgakov's use of Sophia, very few comprehensive, critical studies of Bulgakov's sophiology, spanning its historical development, exist. This article seeks to fill this void at a time when Bulgakov's sophiology is enthusiastically adopted by many without an accompanying critical lens.
Short-Term Health Policy Responses to Crisis and Uncertainty
Authors: HORNUNG JOHANNA , BANDELOW NILS C. 
Published: March 2021

AbstractThe onset of the economic crisis more than a decade ago posed extreme challenges to health care systems that may now be repeated with the COVID-19 pandemic. The resulting policies produced a wide range of (in some cases, even opposite) outcomes: increased or decreased public expenditures for health care. Curiously, however, countries that were considered particularly hard hit by the economic crisis showed different extremes of policy outcomes. Investigating these developments requires a dynamic view and identifying explanations for government action in one direction or the other. Using the lenses of several theoretical perspectives in public policy research, this article analyses the conditions under which public health expenditures changed in European Union member states after the financial crisis. Why did certain countries, at first sight similarly affected, show opposite outcomes? A Qualitative Comparative Analysis (QCA) confirms that left-wing governments and coordinated market economies, in combination and alone, tended to increase public health expenditures in the short term, whereas countries where neither of these conditions was present decreased public health expenditures.
The Republic at the Table, with Decolonisation on the Agenda: The United Nations Security Council and the Question of Indonesian Representation, 1946–1947
Authors: Foray Jennifer L. 
Published: March 2021

AbstractThis article examines a formative episode in the history of both the United Nations Security Council and Indonesian decolonisation. In August of 1947, Council members authorised an ad hoc delegation from the Republic of Indonesia to participate in its discussions concerning the ongoing Dutch–Indonesian conflict. Focusing on the series of developments that led to the Indonesians taking their seats at the table, this article reveals how Security Council procedures and practices could be used to facilitate the decolonisation process. The Council's involvement in the Dutch–Indonesian conflict—and, in particular, the decision to allow the Indonesians to present their case in this international arena—demonstrates that Europeans’ claims of “domestic jurisdiction” over their colonial territories remained subject to negotiation, and that non-European actors could successfully contest these claims in Council chambers.
An evaluation of a group-based cognitive behavioural therapy intervention for low self-esteem
Authors: Swartzman Samantha , Kerr Jenny , McElhinney Rowena 
Published: March 2021

AbstractBackground:Self-esteem is a common factor in many mental health problems, including anxiety and depression. A cognitive behavioural therapy (CBT)-based protocol called ‘Overcoming Low Self-Esteem’ is available; the use of this protocol in a group format has been associated with improvements in self-esteem. However, it is unclear whether improvements persist after the end of a group-based version of this programme.Aims:We aimed to assess whether changes in self-esteem, anxiety and depression persist 3 months after the end of a group version of the Overcoming Low Self-Esteem programme.Method:Using data from the National Health Service in Fife, Scotland, we analysed whether there were improvements on self-report measures of self-esteem, anxiety and depression from the beginning of the group to the end of the group and at a follow-up session 3 months later.Results:Significant improvements in self-esteem, anxiety and depression are maintained at 3 months follow-up.Conclusions:The Overcoming Low Self-Esteem group seems to be associated with improved self-esteem, anxiety and depression. However, further research from randomised controlled trials is needed to establish a causal link between the programme and improved psychological outcomes.
The implementation of the nationwide out-of-hours phone number 1733 in Belgium: analysis of efficiency and safety
Authors: Schoenmakers Birgitte , Delmeiren Lukas , Pietermans Sjors , Janssens Marco , Van Der Mullen Chris , Sabbe Marc 
Published: March 2021

AbstractBackground:Belgium has a problem with inappropriate use of emergency services. The government installed the number 1733 for out-of-hours care. Through a dry run test, we learned that 30% of all calls were allocated to the protocol ‘unclear problem’. In only 11.9% of all cases, there was an unclear problem.Methods:The study aimed to determine whether the adjusted protocol ‘unwell for no clear reason’ led to a safer and more efficient referral and to evaluate the efficiency and safety of the primary care protocols (PCPs). The study ran in cross-sectional design involving patients, General Practitioner Cooperatives and telephone operators. A random sample of calls to 1733 and patient referrals were assessed on efficiency and safety.Results:During 6 months in 2018, 11 622 calls to 1733 were registered. Seven hundred fifty-six of them were allocated to ‘unwell for no clear reason’, and a random sample of 180 calls was audited. To evaluate the PCPs, 202 calls were audited. The efficiency and safety of the protocol ‘unwell for no clear reason’ improved, and safety levels for under- and over-triage were not exceeded. The GP’s judged that 9/10 of all patient encounters were correctly referred.Conclusion:This study demonstrated that the 1733-telephone triage system for out-of-hours care is successful if protocols, flow charts and emergency levels are well defined, monitored and operators are trained.
Tidal Variations in the Mesosphere and Lower Thermosphere Before, During, and After the 2009 Sudden Stratospheric Warming
Authors: Liu Guiping , Lieberman Ruth S. , Harvey V. Lynn , Pedatella Nicholas M. , Oberheide Jens , Hibbins Robert E. , Espy Patrick J. , Janches Diego 
Published: March 2021

AbstractThis work presents a comprehensive evaluation of tides in the mesosphere and lower thermosphere (MLT) of the Whole Atmosphere Community Climate Model with thermosphere‐ionosphere eXtension (WACCMX) and data assimilation provided by the Data Assimilation Research Testbed (DART) ensemble Kalman filter. A total of 26 diurnal and semidiurnal tidal components are calculated using the latest hourly data assimilation cycling during January 12–March 15, 2009 time period. When averaged over this entire yaw cycle, most tidal components display a latitudinal and vertical structures similar to that observed by the Sounding of the Atmosphere using Broadband Emission Radiometry (SABER). However, WACCMX + DART amplitudes of some diurnal tidal components are a factor of ∼1.2–2 times smaller and the peak altitudes and latitudes are shifted compared to SABER. The amplitudes of semidiurnal tides are likewise underestimated in the model, as well as being shifted in altitude and latitude, and some wavenumbers are not captured. Daily tidal variations are calculated in the model and compared with SABER and Super Dual Auroral Radar Network (SuperDARN) radar observations. Both the model and the radars show an amplification of the migrating semidiurnal tide during the week following the peak SSW. Enhancements in nonmigrating diurnal tides are also shown around the SSW peak, which could be produced by the nonlinear interaction between migrating tides and planetary waves. This study finds that, despite using data assimilation to constrain model dynamics, more work is needed in order to accurately simulate the full tidal spectrum and responses to SSWs in the MLT region.
3D Local Earthquake Tomography of the Ecuadorian Margin in the Source Area of the 2016 Mw 7.8 Pedernales Earthquake
Authors: León‐Ríos Sergio , Bie Lidong , Agurto‐Detzel Hans , Rietbrock Andreas , Galve Audrey , Alvarado Alexandra , Beck Susan , Charvis Philippe , Font Yvonne , Hidalgo Silvana , Hoskins Mariah , Laigle Mireille , Oregioni Davide , Meltzer Anne , Ruiz Mario , Woollam Jack 
Published: March 2021

AbstractBased on manually analyzed waveforms recorded by the permanent Ecuadorian network and our large aftershock deployment installed after the Pedernales earthquake, we derive three‐dimensional Vp and Vp/Vs structures and earthquake locations for central coastal Ecuador using local earthquake tomography. Images highlight the features in the subducting and overriding plates down to 35 km depth. Vp anomalies (∼4.5–7.5 km/s) show the roughness of the incoming oceanic crust (OC). Vp/Vs varies from ∼1.75 to ∼1.94, averaging a value of 1.82 consistent with terranes of oceanic nature. We identify a low Vp (∼5.5 km/s) region extending along strike, in the marine forearc. To the North, we relate this low Vp and Vp/Vs (<1.80) region to a subducted seamount that might be part of the Carnegie Ridge (CR). To the South, the low Vp region is associated with high Vp/Vs (>1.85) which we interpret as deeply fractured, probably hydrated OC caused by the CR being subducted. These features play an important role in controlling the seismic behavior of the margin. While subducted seamounts might contribute to the nucleation of intermediate megathrust earthquakes in the northern segment, the CR seems to be the main feature controlling the seismicity in the region by promoting creeping and slow slip events offshore that can be linked to the updip limit of large megathrust earthquakes in the northern segment and the absence of them in the southern region over the instrumental period.