bluuebunny/crossref_metadata_2025_split huggingface dataset:
“The Relative Impact of Barriers to Care Among Military Health Services Personnel: Exploring Differences Using Context Specific Scenarios”
Authors: Born Jennifer , Frank Christine 
Published: June 2021

Abstract
Background: Military health care providers often under access both physical and mental health care, yet research has predominantly focused on barriers to mental health care. This study explored a comprehensive set of barriers using hypothetical scenarios to quantify barrier impact on access to both mental and physical health care. Methods: Canadian military health services personnel (N = 1033) completed one of two electronic surveys (assessing either physical health or other mental health barriers) that captured participant’s demographics, health, endorsement of barriers, intent to seek care, and whether the respondent would access care in different health scenarios (pneumonia, back injury, depression and post-traumatic stress disorder). Logistic regression was used to calculate odds of not accessing care (versus accessing care) for each of the four health scenarios.Results: All barrier factors independently predicted increased odds of not accessing care for all four scenarios. When entered into an adjusted model none of the barrier factors significantly predicted accessing care in the physical health scenarios. Staffing and workload resources and Intention to self-treat were significant predictors of accessing care in the mental health scenarios. Weak general intentions to access care was the strongest predictors of not accessing care across all four scenarios.Conclusions: The impact of barriers on simulated accessing care behaviour differs depending on the context for which one is accessing care, with access to resources and intent to self-treat driving mental health care seeking. Intent appears to be the most impactful predictor of accessing care potentially mediating the effect of other barrier types on care seeking.
Physical Activity and Its Determinants Among Senior Residents of Podlasie, A Green Region of Poland, Based on the National PolSenior Study
Authors: Rowiński Rafał , Kowalska Grażyna , Kozakiewicz Mariusz , Kornatowska Kornelia , Kornatowski Maciej , Hawlena Joanna , Rowińska Karolina 
Published: June 2021

Abstract

Background: Physical activity (PA) is essential at all stages of life, and particularly so in the later years. The aim of the present work was to evaluate the PA of seniors, aged 65 years and older, living in the area of the Podlaskie voivodeship (Podlasie), Poland.Methods: The study was performed as part of the national PolSenior project, whose aim was to evaluate various aspects of aging in Poland. The physical activity of a group of 186 randomly-selected people aged 65 years and above, 94 men and 92 women, was evaluated by questionnaire. The analysis included participants who took part in physical activity at least several times a week. Results: Although all participants reported a decline in PA with age, the men remained physically active for longer. Among the respondents, 68.3% of women and 62.7% of men took short walks around the house as the main form of exercise, with working on the allotment or garden being another frequent activity; however, this was more common among men (53.9%) than women (34.7%). In addition, men were nearly twice as likely to take part in cycling (31.5%) than women (13.1%). The greatest motivation for physical activity given by the respondents was health, as noted by 73.8% of the men and 77.7% of the women. Conclusion: The physical activity (PA) of seniors in Podlasie is unsatisfactory and does not fulfil the WHO recommendations regarding the prophylaxis and prevention of chronic illness. This level does not, however, significantly differ from that reported in the nationwide PolSenior study or in other European countries in the Eurobarometer study. The decline in PA with age highlights the need for its greater promotion among seniors by local authorities. Such initiatives will help maintain the physical fitness and independence of this age group and contribute to a greater quality of life.
Model-free Adaptive Control Design for Chaotic Systems Via Type-2 Recurrent Wavelet Fuzzy Brain Emotional Learning Networks
Authors: Zou Xiaohua , Yang Qingfeng , He Feng , Ling Mingsheng , Dai Jianping 
Published: June 2021

Abstract
This paper introduces an optimal model named Self-Organizing Type-2 Recurrent Wavelet Fuzzy Brain Emotional Learning Network controller (SET2RWFBELNC) with self-evolving algorithm to gain optimal structure from zero initial rule, which merges Interval Type-2 Recurrent Wavelet Fuzzy System and Brain Emotional Learning Network(BELN). As an ideal controller, SET2RWFBELNC not only solves the problem of less information between master and slave systems, but also reduces the influence of external disturbance on synchronization of chaotic systems. Consequently, one model-free adaptive sliding mode controller based on SET2RWFBELNC, sliding model theory, and the asymptotic stability of the synchronization error is realized by robust compensation, in which the strong compensation used for the compensation of the network error. Besides, the Lyapunov function improves the stability of the model. Finally, simulation results of the chaotic system presented in this paper show the superiority of this method. INDEX TERMS Type-2 recurrent wavelet fuzzy system, Sliding mode control, Brain Emotion Learning Network, Model-free adaptive control,Chaotic system.
Host Immunity Biomarkers of Neonatal Sepsis: a Prospective, Multicentre Study in Sub Saharan Africa
Authors: Ezinmegnon Sem , Mommert Marine , Bartolo Francois , Agbota Gino , Darius Sossou , Briand Valérie , d’Almeida Marceline , Alao Maroufou Jules , Dossou-Dagba Ida , Massougbodji Achille , Lausten-Thomsen Ulrik , Pachot Alexandre , Vachot Laurence , Yugueros-Marcos Javier , Brengel-Pesce Karen , Fievet Nadine , Tissieres Pierre 
Published: June 2021

Abstract
Background: Few biomarkers for sepsis diagnosis are commonly used in neonatal sepsis. Whilst host response is increasingly recognized in sepsis pathogenesis and prognosis, there is a need for evaluating the accuracy of new biomarkers targeting host response in regions where sepsis burden is high and medico-economic resources are scarce. The objective of the study is to evaluate diagnostic and prognostic accuracy of biomarkers of neonatal sepsis in Sub Saharan Africa. Methods: Prospective multicentre study conducted between April 2016 and March 2018 in three University hospitals and two sub-urbans healthcare centres in the south Benin region. Patients were followed from birth to 3 months of age. Accuracy of transcriptional (CD74, CX3CR1), proteic (PCT, IL-6, IL-10, IP-10) biomarkers and clinical characteristics to diagnose and prognose neonatal sepsis were measured. At delivery, cord blood from all consecutive newborns were sampled and analysed, and infants were followed for a 12 weeks’ period. Results: From April 17, 2016 through March 12, 2018, a total of 581 newborns were enrolled. One hundred and seventy-two newborns developed neonatal sepsis (29.6%) and death occurred in forty-nine infants (8.4%). Among all tested biomarkers and clinical criteria, CD74/IP-10 ratio showed the best accuracy for neonatal sepsis diagnosis, while PCT accuracy was low. Among biomarkers and clinical criteria studied, only CD74 and PCT were independently associated with mortality, with CD74 showing an elevated predictive accuracy. Conclusion: Cord blood PCT had a low accuracy for diagnosing early onset neonatal sepsis in Sub Saharan African neonates, while CD74/IP-10 ratio had the best diagnostic accuracy. CD74 expression at birth had the best accuracy in prognosing sepsis mortality.Trial registration: Clinicaltrial.gov registration number: NCT03780712. Registered 19 December 2018. Retrospectively registered
Study on the Diversity of Epiphytic Bacteria on Corn and Alfalfa using Illumina MiSeq/NovaSeq High-throughput Sequencing System
Authors: Wu Mei-Xiao , Tang hui 
Published: June 2021

Abstract
PurposeTo investigate the diversity of the epiphytic bacteria on corn and alfalfa collected in Hengshui city and Xingtai city, hebei province, China.MethodsIllumina MiSeq/NovaSeq High-throughput sequencing systerm was used to conduct Paired-end sequencing of community DNA fragments from surface of corn and alfalfa in Hengshui and Xingtai. QIIME2 and R language were employed to sort and calculate the number of sequences and taxonomic units for each sample. Thereafter, the abundance, distribution, alpha diversity index of species, beta diversity and the differences of abundance among the samples were analyzed. ResultAt phylum level, the advantage bacterium group are Proteobacteria (70%), Firmicutes (13%), Actinobacteria (9%) and Bacteroidetes (7%). The dominant genera are Pseudomonas (8%), Acinetobacter (4%), Chryseobacterium (3%), Hymenobacter (1%). Enterobacteriaceae (24%) are the most predominant bacteria on both corn and alfalfa samples. Alpha diversity analysis and beta diversity analysis showed that the diversity of epiphytic microbial community was significantly affected by plant species, but not by region. The diversity and richness of epiphytic bacterial community of alfalfa were significantly higher than that of corn, yet corn had more LAB than alfalfa samples. ConclusionThis study contributes to expanding our understanding of the diversity of epiphytic microorganisms in corn and alfalfa silage and provide a basis for the selection of raw materials.
Ischemia Is an Efficient Predictor of Significant Coronary Artery Disease in Routine Reports of a Large-scale Clinical Cohort Using Very Low-dose Exercise-first Myocardial Perfusion SPECT
Authors: Chawki Mohammad Bilal , Goncalves Trecy , Boursier Caroline , Bordonne Manon , Verger Antoine , Imbert Laetitia , Perrin Mathieu , Claudin Marine , Roch Veronique , Djaballah Karim , Popovic Batric , Camenzind Edoardo , Marie Pierre-Yves 
Published: June 2021

Abstract
Purpose. This study assesses results from large-scale and real-life routine interpretations by multiple observers of very low-dose exercise-first myocardial perfusion SPECT imaging (MPI) and the correlation of MPI ischemia with subsequent routine reports of coronary stenosis by angiography. Methods. Data from 13,126 routine exercise-MPI reports, from 11,952 patients (31% women), using very low doses of Sestamibi and a high-sensitivity cardiac CZT-camera, were extracted to assess the reporting of significant MPI-ischemia (> 1 left ventricular segment), to determine the normalcy rate for MPI in a group with < 5% pretest likelihood of coronary artery disease (CAD) (n=378), and to assess the ability of MPI to predict a > 50% coronary stenosis in patients with available coronary angiography reports within the next three months of MPI (n=713). Results. The median of patients’ effective dose was 2.51 [IQR: 1.00-4.71] mSv. The normalcy rate was 97%, and the MPI-ischemia rate was independently related to a previous CAD history, the male gender, obesity, and a < 50% resting LV ejection fraction, ranging from 31% with all these risk factors represented, to 2% when there were no risk factors. A > 50% coronary stenosis was significantly predicted by MPI-ischemia, less significantly for mild (odd-ratio [95% confidence interval]: 1.61 [1.11-2.32]) than for moderate-to-severe MPI-ischemia (3.91 [2.24-6.84]), and was also impacted by a history of CAD (2.31 [1.56-3.44]), a sub-maximal exercise test (1.61 [1.11-2.34]) and age ≥ 65 years (1.41 [1.00-1.97]). Conclusion. Ischemia is an efficient predictor of significant CAD in routine reports of a large-scale clinical cohort and using a very low-dose exercise-first MPI protocol, although this prediction is enhanced by other variables. This weakly irradiating investigation could likely be repeated at shorter time intervals, especially in targeted patient groups with high risk of ischemia.
Identification of Campylobacter Jejuni and Chlamydia Psittaci From cockatiel (Nymphicus Hollandicus) Using Metagenomics
Authors: Kim Si-Hyeon , Kwon Yong-Kuk , Park Choi-Kyu , Kim Hye-Ryoung 
Published: June 2021

Abstract
BackgroundIn July 2015, the carcasses of 11 cockatiels were submitted for disease diagnosis to the Avian Disease Division of the Animal and Plant Quarantine Agency of Korea. The cockatiels, which appeared dehydrated and underweight, had exhibited severe diarrhea and 22% mortality over 2 weeks. Traditional diagnosis did not reveal the causes of these symptoms. MethodsWe conducted metagenomics analysis on intestines and livers from the dead cockatiels using Illumina high-throughput sequencing. To obtain more accurate and longer contigs, which are required for further genetic characterization, we compared the results of three de novo assembly tools (metaSPAdes, MEGAHIT, and IDBA-UD).ResultsSequence reads of Campylobacter jejuni (C. jejuni) and Chlamydia psittaci (C. psittaci) were present in most of the cockatiel samples. Either of these bacteria could cause the reported symptoms in psittaciformes. metaSPAdes (ver.3.14.1) identified the 1152 bp flaA gene of C. jejuni and the 1096 bp ompA gene of C. psittaci. Genetic analysis revealed that flaA of C. jejuni was recombinant between C. jejuni and Campylobacter coli, and that ompA of C. psittaci isolated from cockatiel was closely related to strains isolated from humans. ConclusionC. jejuni and C. psittaci were detected in cockatiels in the Republic of Korea using metagenomic analysis. This approach is useful for understanding pathogens of pet birds. Three de novo assemblers were compared to obtain accurate contigs from large quantities of reads, and sequences of C. jejuni and C. psittaci generated by metaSPAdes were analyzed.
The gut bacterial natural product colibactin triggers induction of latent viruses in diverse bacteria
Authors: Silpe Justin E. , Wong Joel W. H. , Owen Siân V. , Baym Michael , Balskus Emily P. 
Published: June 2021

Abstract
Colibactin is a chemically unstable small molecule genotoxin produced by multiple different bacteria, including members of the human gut microbiome. While the biological activity of colibactin has been extensively investigated in mammalian systems, little is known about its effects on other microorganisms. Here, we discover that colibactin targets bacteria carrying prophages, inducing lytic development via the bacterial SOS response. DNA, added exogenously, protects bacteria from colibactin, as does expressing a colibactin resistance protein (ClbS) in non-colibactin-producing cells. The prophage-inducing effects we observe apply broadly across taxonomically diverse phage-bacteria systems. Finally, we identify bacteria that possess colibactin resistance genes but lack colibactin biosynthetic genes. Many of these bacteria are infected with predicted prophages, and we show that the expression of their ClbS homologs provides immunity from colibactin-triggered induction. Our study reveals a mechanism by which colibactin production could impact microbiomes and highlights an underappreciated role for microbial natural products in influencing population-level events such as phage outbreaks.
Fermi surface tomography
Authors: Borisenko Sergey , Fedorov Alexander , Andrii Kuibarov , Bianchi Marco , Bezguba Volodymyr , Majchrzak Paulina , Hofmann Philip , Baumgärtel Peter , Voroshnin Vladimir , Kushnirenko Yevhen , Sánchez-Barriga Jaime , Varykhalov Andrei , Ovsyannikov Ruslan , Morozov Igor , Aswartham Saicharan , Feia Oleh , Harnagea Luminita , Kordyuk Alexander , Yaresko Alexander , Berger Helmuth , Büchner Bernd 
Published: June 2021

Abstract
Fermi surfaces, three-dimensional (3D) abstract interfaces that define the occupied energies of electrons in a solid, are important for characterizing and predicting the thermal, electrical, magnetic, and optical properties of crystalline metals and semiconductors [1]. Angle-resolved photoemission spectroscopy (ARPES) is the only technique directly probing the Fermi surface by measuring the Fermi momenta ( kF ) from energy- and angular distribution of photoelectrons dislodged by monochromatic light [2]. Existing electron analyzers are able to determine a number of kF -vectors simultaneously, but current technical limitations prohibit a direct high-resolution 3D Fermi surface mapping. As a result, no such datasets exist, strongly limiting our knowledge about the Fermi surfaces and restricting a detailed comparison with the widely available nowadays calculated 3D Fermi surfaces.
Here we show that using a simpler instrumentation, based on the Fourier electron optics combined with a retardation field of the detector, it is possible to perform 3D-mapping within a very short time interval and with very high resolution. We present the first detailed experimental 3D Fermi surface recorded in the full Brillouin zone along the kz-direction as well as other experimental results featuring multiple advantages of our technique. In combination with various light sources, including synchrotron radiation, our methodology and instrumentation offer new opportunities for high-resolution ARPES in the physical and life sciences.
Finding a rIsk assessmeNt moDel for thromboembolic events in hospItalized Cancer pATiEnts: the INDICATE study running title: thromboembolism in hospitalized cancer patients
Authors: Nichetti Federico , Ligorio Francesca , Montelatici Giulia , Porcu Luca , Zattarin Emma , Provenzano Leonardo , Franza Andrea , Lalli Luca , De Braud Filippo , Platania Marco 
Published: June 2021

Abstract
Background: Hospitalized cancer patients are at increased risk for Thromboembolic Events (TEs). As untailored thromboprophylaxis is associated with hemorrhagic complications, the definition of a risk-assessment model (RAM) in this population is needed. Objectives: INDICATE was an observational study enrolling hospitalized cancer patients, with the primary objective of assessing the Negative Predictive Value (NPV) for TEs during hospitalization and within 45 days from discharge of low-grade Khorana Score (KS=0). Secondary objectives were to assess KS Positive Predictive Value (PPV), the impact of TEs on survival and the development of a new RAM. Materials and Methods: Assuming 7% of TEs in KS=0 patients as unsatisfactory percentage and 3% of as satisfactory, 149 patients were needed to detect the favorable NPV with one-sided a= 0.10 and power=0.80. Stepwise logistic regression was adopted to identify variables included in a new RAM.Results: Among 535 enrolled patients, 153 (28.6%) had a KS=0. The primary study objective was met: 29 (5.4%) TEs were diagnosed, with 7 (4.6%) cases in the KS=0 group (NPV=95.4%, 95%CI: 90.8-98.1%; one-sided p=0.084). However, the PPV was low (5.7%, 95%CI: 1.9-12.8%); a new RAM based on albumin (OR 0.34, p=0.003), log(LDH) (OR 1.89, p=0.023) and presence of vascular compression (OR 5.32, p<.001) was developed and internally validated. Also, TEs were associated with poorer OS (median, 5.7 vs 24.8 months, p <.001).Conclusion: INDICATE showed that the KS has a good NPV but poor PPV for TEs in hospitalized cancer patients. A new RAM was developed, and deserves further assessment in external cohorts.
Coaxial Drainage Versus Standard Chest Tube After Pulmonary Lobectomy: A Randomized Controlled Study
Authors: Bassi Massimiliano , Mottola Emilia , Mantovani Sara , Amore Davide , Pagini Andreina , Diso Daniele , Poggi Camilla , Vannucci Jacopo , De Giacomo Tiziano , Rendina Erino Angelo , Venuta Federico , Anile Marco 
Published: June 2021

Abstract
Objectives: Chest tubes are routinely inserted after thoracic surgery procedures in different size and numbers. The aim of this study is to assess the efficacy of Smart Drain Coaxial drainage compared with two standard chest tubes in patients undergoing thoracotomy for pulmonary lobectomy.Methods: Ninety-eight patients (57 males and 41 females, mean age 68.3±7.4 years) with lung cancer undergoing open pulmonary lobectomy were randomized in two groups: 50 received one upper 28-Fr and one lower 32-Fr standard chest tube (ST group) and 48 received one 28-Fr Smart Drain Coaxial tube (SDC group). Hospitalization, quantity of fluid output, air leaks, radiograph findings, pain control and costs were assessed.Results: We performed 33 right upper lobectomies (17 ST, 16 SDC), 25 right lower (15 ST, 10 SDC), 20 left upper (8 ST, 12 SDC) and 19 left lower (10 ST, 9 SDC). SDC group showed shorter hospitalization (7.3 vs 6.1 days, p=0.02), lower pain in postoperative day-1 (p=0.02) and a lower use of analgesic drugs (p=0.04). Pleural effusion drainage was lower in SDC group in the first postoperative day (464±143 ml vs 408±141 ml, p=0.04) and regarding the average of the first three days (374±96 ml vs 324±95 ml, p=0.01). No difference in terms of fluid retention, residual pleural space, subcutaneous emphysema and complications after chest tubes removal was found. Conclusions: Smart Drain Coaxial chest tube seems a feasible option after thoracotomy for pulmonary lobectomy. The SDC group showed a shorter hospitalization and a decreased analgesic drugs use and, thus, a reduction of costs.
Adsorption/desorption performance of Pb2+ and Cd2+ with super adsorption capacity of PASP/CMS hydrogel
Authors: Wang Hao , Zhao Baiyun , Wang Li 
Published: June 2021

Abstract
Super-absorbent polyaspartic acid/carboxymethyl Salix psammophila powder (PASP/CMS) hydrogel was prepared by aqueous solution polymerization. PASP/CMS hydrogel was characterized by Fourier-transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). The results showed that PASP/CMS hydrogel is prepared by graft copolymerization of the -COOH of polyaspartic acid (PASP) and the -CH2OH of CMS. The surface of the hydrogel became dense from loose porosity, and Pb2+ and Cd2+ were adsorbed onto the surface of hydrogel. The crystallinity of CMS was destroyed by the addition of PASP. The initial concentration of Pb2+ and Cd2+, pH, adsorption time and adsorption temperature on the adsorption effect were studied through experiments. Results showed that hydrogel has a good removal effect on Pb(II) and Cd(II) ions. Pseudo-second-order kinetics and Langmuir isotherm models are represented in the process, which are spontaneous, exothermic and decreased in randomness, and it is a single layer chemical adsorption. At the same time, the effect of desorption experimental parameters (HNO3 initial concentration, desorption time, and desorption temperature) on the experiment was studied and optimized.