bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on the reconfiguration and switching of subcarriers in all‐optical orthogonal frequency division multiplexing system
Authors: Chao Yu , Chen Genxiang , Tian Qinghua , Zhang Xiaoyu 
Published: January 2021

AbstractWe propose a subcarrier‐switching method for all‐optical orthogonal frequency division multiplexing (AO‐OFDM) system. In addition, analysis of the affected neighboring subcarriers, along with the subcarriers being added or dropped, is carried out in a comprehensive manner. After switching operation four times, target subcarrier can still have a Q value larger than 27, while Q value of neighboring orthogonal subcarriers exceeds 31 in AO‐OFDM system with 16 orthogonal subcarriers.
Factors determining acceptance of disease and its impact on satisfaction with life of patients with peripheral artery disease
Authors: Piotrkowska Renata , Terech‐Skóra Sylwia , Mędrzycka‐Dąbrowska Wioletta , Jarzynkowski Piotr , Król Magdalena 
Published: January 2021

AbstractAims and objectivesAnalysis of factors determining acceptance of disease and satisfaction with life in patients with peripheral artery disease.BackgroundPeripheral artery disease is more common in older patients and is associated with increased morbidity and mortality due to cardiovascular diseases and the risk of amputation. The acceptance of disease is one of the most important factors for adjusting to life with a chronic disease.DesignA cross‐sectional survey study. Patients’ questionnaires.MethodThe participants were patients with peripheral artery disease (N = 72). The study included the use the standardized research tools the Acceptance of Illness Scale (AIS) and the Satisfaction with Life Scale (SWLS).ResultsThe highest acceptance of disease was observed for patients with higher education, while the lowest was found for patients with the greatest limitation of physical mobility.ConclusionsThe education level and physical fitness of patients had significant impact on disease acceptance.
Effectiveness of nurses and midwives‐led psychological interventions on reducing depression symptoms in the perinatal period: A systematic review and meta‐analysis
Authors: Wang Tsuei‐Hung , Pai Lee‐Wen , Tzeng Ya‐Ling , Yeh Tzu‐Pei , Teng Yu‐Kuei 
Published: January 2021

AbstractAimTo evaluate the effectiveness of nurses and midwives‐led psychological interventions on the perinatal depressive symptoms.DesignA systematic review and meta‐analysis based on the PRISMA guidelines.MethodsSix databases were searched, including PubMed, MEDLINE, Cochrane Library, EMBASE, Web of Science and CINAHL. The search date range was before 30 September 2019. We used the Cochrane risk of bias tool to evaluate the quality of the included studies and Review Manager software 5.3 to conduct a meta‐analysis. The data were pooled using a random‐effect model.ResultsStudies (N = 827) were retrieved with 12 studies included. Psychological interventions provided by nurses and midwives have a significant effect on reducing perinatal depressive symptoms (RR: 0.72, 95% CI [0.64–0.82]). Among the approaches of psychological intervention, supportive counselling was the most effective (RR: 0.58, 95% CI [0.42–0.80]). The best intensity of intervention was six to eight sessions (RR: 0.66, 95% CI [0.55–0.79]).
Hidden layer imaging using joint inversion of P‐wave travel‐time and electrical resistivity data
Authors: Yari Mostafa , Nabi‐Bidhendi Majid , Ghanati Reza , Shomali Zaher‐Hossein 
Published: January 2021

ABSTRACTThe combination of geophysical surface‐based imaging techniques, including seismic and electrical resistivity tomography (ERT), is now common practice to obtain a more accurate characterization of subsurface structures. Due to model non‐uniqueness and geological heterogeneity, conventional travel‐time tomography cannot solely reveal hidden layers (i.e., low‐velocity zones embedded between layers of higher velocities) in the subsurface. Hence, we present a joint inversion algorithm based on a normalized cross‐gradients function to detect hidden low‐velocity layers. The structural similarity between P‐wave velocity (Vp) and resistivity fields is enhanced by incorporating the normalized cross‐gradients constraint in the joint inversion algorithm. Improved structural similarity can mitigate the problem of the recovery of a hidden layer. We also take advantage of a priori information derived from borehole geological data to reduce the continuous range of possible solutions (i.e., exact‐data non‐uniqueness). In both joint and separate inversions, an auxiliary damping factor is used to ensure convergence, and also the smoothness constraints are applied to deal with instability stemming from error in the data. To verify the performance of the joint inversion procedure, the algorithm is tested on synthetic and real data examples with emphasis on hidden low‐velocity layer detection. Numerical experiments demonstrate that the joint inversion strategy can produce more reliable and better velocity models of the subsurface structures as compared with those obtained through individual inversions. We conclude that this simultaneous joint inversion of Vp and ERT integrates the best of both schemes and makes it possible to improve resolution, and, hence, reduces uncertainties in hidden low‐velocity layer problems.
Origin and distribution of ancient Thai pig lineages
Authors: Chittavichai Thanyaporn , Surat Wunrada , Wetchaphan Sulak , Poungpan Supanat , Boonmala Sukumal , Netmanee Suppakorn , Auetrakulvit Prasit , Khunsong Saritpong , Wattanapituksakul Athiwat , Shoosongdej Rasmi , Wonnapinij Passorn 
Published: January 2021

AbstractWhether animal domestication in Mainland Southeast Asia (MSEA) developed locally or began with the introduction of domesticated pigs from present‐day China has been discussed at length. This study compared the mitochondrial control region (mtCR) sequences of ancient pig samples from various Thai archeological sites to ancient Chinese pigs and modern Asian pigs. Twenty‐one samples (including eight previously reported ones) from six archeological sites located in three areas of Thailand were applied to haplotype analysis along with 2005 sequences of ancient Chinese pigs and modern Asian pigs. The haplotype network showed that genetic diversity and relationship with ancient Chinese pigs suggested multiple origins of ancient Thai maternal lineages, located in present‐day China and MSEA, specifically Thailand. The distinct mtCR haplotypes found in western compared with those found in eastern and central ancient Thai pigs suggested two possible routes of the past migration. These routes corresponded to the movement of agriculturists from present‐day China to MSEA. Several shared haplotypes found between ancient Thai pigs from different archeological sites suggested people contact in the past. Most ancient Thai pigs left their descendants in the contemporary Asian population. Hence, it was proposed that most maternal ancestors of ancient Thai pigs migrated from present‐day Southern China to MSEA via two routes with some local gene flow degrees and left their descendants in Thailand. These results would pave the way for future studies focusing on the history of MSEA pig domestication.
Bushmeat skeletal waste from an Atlantic African rainforest (Equatorial Guinea) as a test for the Mammal Community Structure Analysis in paleoecology
Authors: Rosas Antonio , Aguado Lorena , García‐Tabernero Antonio , Saladié Palmira , Fero Meñe Maximillano , Ebana Cayetano , Esono Mba Fidel , Morales Juan Ignacio , Andrews Peter 
Published: January 2021

AbstractMammalian Community Structure Analysis (MCSA) is a widely used paleoecological method for reconstructing environments in fossil sites where apes and hominins are present. However, any fossil assemblage is the result of complex ecological and taphonomic processes that may obscure biological interpretation. In this work, we test the validity of the MCSA for the reconstruction of African rain forest environments through an actualistic approach. For this purpose, we compare the living Mammalian Community Structure of the National Park of Monte Alen (MA) and surrounding areas (Equatorial Guinea, Río Muni) with the one inferred from associations of skeletal remains (ASRs) collected in villages of the area. It was found that in equatorial rain forest contexts, humans are a significant accumulating agent of skeletal remains, in contrast to other accumulating organisms, which are absent. In villages where hunting of wild animals (bushmeat) is regular, a good number of osteological remains from food residues are deposited near the houses. We collected six samples from five villages and treated each of them as “skeletal associations.” We also considered a cumulative deposit composed by the total sample of 3153 skeletal remains. Mammalian Community Structure was estimated using three ecovariables: weight, locomotor adaptation, and diet. Cluster and Correspondence Analysis of the three ecological variables validated the fauna of MA as that of an African tropical forest. Next, the ASRs were compared with the fauna of MA. Some of the localities allowed accurate environmental reconstruction; however, three “skeletal associations” do not provide the minimum amount of data needed for their characterization, ecological biases being evident. The skeletal assemblage that best matches the living reference community is the composite sample. From a paleoecological reconstruction viewpoint, the tropical forest signal is conserved when evaluating percentage relationships between the most diagnostic ecovariables, particularly fruit‐eating mammals versus carnivores and arboreal mammals. Taken together, the MCSA is effective in detecting African tropical ecosystems.
A Bronze Age mandibular anomaly from Gansu, China
Authors: Yang Shiyu , Mao Ruilin , Zhang Quanchao , Wang Qian 
Published: January 2021

AbstractBone defect in the mandible due to developmental defects, trauma, or diseases is common. However, large scale of mandibular bone atrophy induced by long‐term pressure is rare. This study reported a mandibular anomaly, possibly a secondary lesion, from a Bronze Age adult male excavated from the Dunping cemetery during the Eastern Zhou Dynasty (770–256 BCE), Zhang County, Gansu Province, China. The defect presents as an absence of bone mass at the angle of inferior lingual aspect of the mandibular corpus, incorporating the gonial angle of the mandible on the left side. Overall profile of the defect was assessed using morphological observations of the mandible, accompanied by computed tomography (CT) imaging and panoramic dental X‐ray images of the jaws used to assist with the diagnosis. There were no signs of trauma, osteogenic neoplasms, or osteolytic lesions. Pressure resorption, a Stafne defect, was postulated as the primary cause of bone atrophy due to a long‐term lesion of the neighboring submandibular gland, namely, chronic sialadenitis or a benign neoplasm pleomorphic adenoma. This is for the first reported case of a mandible anomaly as such identified from ancient China. This reporting enriches the knowledge of long‐term effects of pressure resorption in the human mandible.
Effect of surface modification and fiber content on the mechanical performance of compression molded polyethylene‐maple composites
Authors: Vázquez Fletes Roberto Carlos , Raymond Alexandre , Rodrigue Denis 
Published: January 2021

AbstractWith the objective of producing more sustainable materials, wood‐plastic composites were produced using linear low density polyethylene and a wide range of maple wood fiber content (up to 80% wt). This was possible by using a simple dry‐blending of the component in a powder form and compression molding. In particular, the effect of different surface treatments (mercerization, maleated polyethylene [MAPE], and their combination) on the morphology and mechanical performance of these composites was studied. The results show that all the surface treatments investigated were able to improve the fiber‐matrix adhesion, leading to better composite homogeneity, and higher mechanical properties. Furthermore, it was possible to increase the amount of wood that can be introduced in the composites compared to untreated fibers. In our case, up to 80% wt of maple fibers were easily processed generating significant improvements in moduli (367%) and strength (50%), especially when a combination of alkali‐MAPE treatment was performed. This simple processing of the composites is interesting to produce different parts size and geometry with limited degradation since no melt compounding is performed. The work also represents a way to produce sustainable, economic, and lightweight composites with improved properties using a high content of renewable filler.
Effect of solution concentration in microfiltration properties of PLA mats produced by solution blow spinning
Authors: Soares de Azerêdo Marina , Marconcini José Manoel 
Published: January 2021

AbstractIn order to remediate the difficulty of access to safe drinking water by 1/3 of the world population, mats produced by solution blow spinning (SBS) have a great potential for use in liquid filtration due to their small pores and high porosity, being capable of filtrating water by retaining particles and even microorganisms. In this context, this work aims the production and characterization of poly (lactic acid) mat obtained by SBS to be morphologically, thermally, and mechanically evaluated, as well as to observe water flux properties. The correlation between structure‐processing‐properties is an important part of the work, which shows that lower concentration of polymeric solution leads to mats with smaller average fiber diameter, greater crystallinity, impacting on their greater tensile strength. The water flux performance shows that mats obtained from higher polymer concentration solutions present less resistance to the water flow, which indicates larger pore diameters.
In‐depth proteomic analysis of Plasmodium berghei sporozoites using trapped ion mobility spectrometry with parallel accumulation‐serial fragmentation
Authors: Hamada Soumia , Pionneau Cédric , Parizot Christophe , Silvie Olivier , Chardonnet Solenne , Marinach Carine 
Published: January 2021

AbstractSporozoites of the malaria parasite Plasmodium are transmitted by mosquitoes and infect the liver for an initial and obligatory round of replication, before exponential multiplication in the blood and onset of the disease. Sporozoites and liver stages provide attractive targets for malaria vaccines and prophylactic drugs. In this context, defining the parasite proteome is important to explore the parasite biology and to identify potential targets for antimalarial strategies. Previous studies have determined the total proteome of sporozoites from the two main human malaria parasites, P. falciparum and P. vivax, as well as P. yoelii, which infects rodents. Another murine malaria parasite, P. berghei, is widely used to investigate the parasite biology. However, a deep view of the proteome of P. berghei sporozoites is still missing. To fill this gap, we took advantage of the highly sensitive timsTOF PRO mass spectrometer, combined with three alternative methods for sporozoite purification, to identify the proteome of P. berghei sporozoites using low numbers of parasites. This study provides a reference proteome for P. berghei sporozoites, identifying a core set of proteins expressed across species, and illustrates how the unprecedented sensitivity of the timsTOF PRO system enables deep proteomic analysis from limited sample amounts.
Structure of human BCCIP and implications for binding and modification of partner proteins
Authors: Choi Woo Suk , Liu Bochao , Shen Zhiyuan , Yang Wei 
Published: January 2021

AbstractBCCIP was isolated based on its interactions with tumor suppressors BRCA2 and p21. Knockdown or knockout of BCCIP causes embryonic lethality in mice. BCCIP deficient cells exhibit impaired cell proliferation and chromosome instability. BCCIP also plays a key role in biogenesis of ribosome 60S subunits. BCCIP is conserved from yeast to humans, but it has no discernible sequence similarity to proteins of known structures. Here we report two crystal structures of an N‐terminal truncated human BCCIPβ, consisting of residues 61–314. Structurally BCCIP is similar to GCN5‐related acetyltransferases (GNATs) but contains different sequence motifs. Moreover, both acetyl‐CoA and substrate‐binding grooves are altered in BCCIP. A large 19‐residue flap over the putative CoA binding site adopts either an open or closed conformation in BCCIP. The substrate binding groove is significantly reduced in size and is positively charged despite the acidic isoelectric point of BCCIP. BCCIP has potential binding sites for partner proteins and may have enzymatic activity.
Structural basis for substrate specificity of l‐methionine decarboxylase
Authors: Okawa Atsushi , Shiba Tomoo , Hayashi Masaya , Onoue Yuki , Murota Masaki , Sato Dan , Inagaki Junko , Tamura Takashi , Harada Shigeharu , Inagaki Kenji 
Published: January 2021

Abstractl
‐Methionine decarboxylase (MetDC) from Streptomyces sp. 590 is a vitamin B6‐dependent enzyme and catalyzes the non‐oxidative decarboxylation of l
‐methionine to produce 3‐methylthiopropylamine and carbon dioxide. We present here the crystal structures of the ligand‐free form of MetDC and of several enzymatic reaction intermediates. Group II amino acid decarboxylases have many residues in common around the active site but the residues surrounding the side chain of the substrate differ. Based on information obtained from the crystal structure, and mutational and biochemical experiments, we propose a key role for Gln64 in determining the substrate specificity of MetDC, and for Tyr421 as the acid catalyst that participates in protonation after the decarboxylation reaction.
Supermodding – A special footprint operator for mesoscale data assimilation using scatterometer winds
Authors: Mile Máté , Randriamampianina Roger , Marseille Gert‐Jan , Stoffelen Ad 
Published: January 2021

AbstractSatellite observation footprints may extend over many grid points of a high‐resolution limited‐area model, while small and fast model scales may not be traceable by the observing system. We discuss the spatial representation of scatterometer ocean surface winds for the representation of high‐resolution model state variables. A prototype observation operator called supermodding is studied in the variational assimilation framework in order to avoid correcting unconstrained small scales during the assimilation procedure. The challenges connected to small scales that are represented by the mesoscale model with respect to the application of the supermodding operator are discussed through idealised experiments. These results show that the application of the supermodding operator is able to avoid correcting unconstrained small scales, putting focus on the large scales only during data assimilation. Departure‐based diagnostics show that the footprint representation helps to reduce the standard deviation of observation minus background departures (4–5% reduction) while the statistics for the supermodding method show a further reduction (8–11%). The impact of the supermodding approach is discussed through a forecast sensitivity study using a moist total energy norm (MTEN)‐based technique and verification of the forecasts against observations. It is shown that the impact of the supermodding method to ASCAT data assimilation on the upper‐air AROME‐Arctic forecasts is observed over sea and near the surface, and that it is progressively shifted towards 700–800 hPa levels. Both supermodding at 30 km and at 60 km (i.e., twice the effective resolution of the applied scatterometer observations) show significant and consistent improvement on forecasts of lower tropospheric wind and temperature compared to the operational assimilation technique, as such demonstrating the robustness of the supermodding technique.
A novel manipulator with needle insertion forces feedback for robot‐assisted lumbar puncture
Authors: Li Hongbing , Wang Yiyun , Li Yuling , Zhang Jing 
Published: January 2021

AbstractBackgroundThe use of lumbar puncture for paediatric diagnosis and treatment, such as cerebrospinal fluid sampling and intracranial pressure measurements, is steadily increasing. However, the standard ‘blind’ technique makes it difficult to attain accurate needle insertion.MethodsIn this study, we developed a robot‐assisted system to improve the precision of needle insertion during lumbar puncture. The manipulator can perform orientation, insertion and rotation of the needle as well as linear motion at targeted locations. We focused on accurately sensing the puncture forces during the needle insertion phase and evaluated the piercing force perception of the operator.ResultsThe main features of the robot, such as backdrivable joints, physical human–robot cooperation, actuation system with low friction and remote centre of motion mechanism, can enhance overall safety.ConclusionsExperimental results using a lumbar puncture phantom proved that the manipulator could position the needle tip at targeted locations with good accuracy. The data obtained from the test system also showed that the loss of resistance and peak forces for stiff tissues were accurately perceived by the operator.
Implementation of robot‐assisted total mesorectal excision by multiple surgeons in a large teaching hospital: Morbidity, long‐term oncological and functional outcome
Authors: Hol Jeroen C. , Dogan Kemal , Blanken‐Peeters Charlotte F. J. M. , van Eekeren Ramon R. J. P. , de Roos Marnix A. J. , Sietses Colin , Spillenaar Bilgen Ernst J. , Witteman Bart P. L. 
Published: January 2021

AbstractBackgroundRobot‐assisted total mesorectal excision (TME) might offer benefits in less morbidity, better functional and long‐term outcome over laparoscopic TME.MethodsAll consecutive patients undergoing robot‐assisted TME for rectal cancer during implementation between May 2015 and December 2019 performed by five surgeons in a single centre were included. Outcomes included local recurrence rate at 3 years, conversion rate, circumferential resection margin (CRM) positivity rate, 30‐day postoperative morbidity and outcomes of low anterior resection syndrome (LARS) questionnaires.ResultsIn 105 robot‐assisted TME, local recurrence rate at 3 years was 7.4%, conversion to open surgery rate was 8.6%, CRM positivity rate was 5.7%, 73.3% had good quality specimen, postoperative morbidity rate was 47.6% and anastomotic leakage rate was 9.0%. Incidence of major LARS was 55.3%.Conclusionsresults of this study described acceptable morbidity, functional and long‐term outcome during implementation of robotic TME for rectal cancer by multiple surgeons in a single centre.
The behavior of concrete‐encased steel composite column‐beam joints under cyclic loading
Authors: Şermet Fethi , Ercan Emre , Hökelekli Emin , Demir Ali , Arısoy Bengi 
Published: January 2021

SummaryThis study outlines the cyclic loading response of a concrete‐encased steel profile composite column‐reinforced concrete beam connection. The experimental study performed for an interior joint. The column in joint was designed as a concrete‐encased I‐steel profile composite column according to Eurocode 4, and the beam was designed as a regular reinforced concrete beam according to local building codes. In order to emphasize the effect of the joint design, different steel core orientations were used. The numerical analysis was performed using ABAQUS to predict behavior of the joint. The performance of the samples compared the load‐carrying capacity, ductility, and failure type. Comparisons were made using load–displacement relationships and failure mechanisms. The analysis results showed that the failure was determined by the behavior of the beam, and the joint capacity depended on the shear capacity of the beam.