bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magnesium Deficiency Causes a Reversible, Metabolic, Diastolic Cardiomyopathy
Authors: Liu Man , Liu Hong , Feng Feng , Xie An , Kang Gyeoung‐Jin , Zhao Yang , Hou Cody R. , Zhou Xiaoxu , Dudley Samuel C. 
Published: June 2021

Background
Dietary Mg intake is associated with a decreased risk of developing heart failure, whereas low circulating Mg level is associated with increased cardiovascular mortality. We investigated whether Mg deficiency alone could cause cardiomyopathy.

Methods and Results

C57BL/6J mice were fed with a low Mg (low‐Mg, 15–30 mg/kg Mg) or a normal Mg (nl‐Mg, 600 mg/kg Mg) diet for 6 weeks. To test reversibility, half of the low‐Mg mice were fed then with nl‐Mg diet for another 6 weeks. Low‐Mg diet significantly decreased mouse serum Mg (0.38±0.03 versus 1.14±0.03 mmol/L for nl‐Mg;
P
<0.0001) with a reciprocal increase in serum Ca, K, and Na. Low‐Mg mice exhibited impaired cardiac relaxation (ratio between mitral peak early filling velocity E and longitudinal tissue velocity of the mitral anterior annulus e, 21.1±1.1 versus 15.4±0.4 for nl‐Mg;
P
=0.011). Cellular ATP was decreased significantly in low‐Mg hearts. The changes were accompanied by mitochondrial dysfunction with mitochondrial reactive oxygen species overproduction and membrane depolarization. cMyBPC (cardiac myosin‐binding protein C) was
S
‐glutathionylated in low‐Mg mouse hearts. All these changes were normalized with Mg repletion. In vivo (2‐(2,2,6,6‐tetramethylpiperidin‐1‐oxyl‐4‐ylamino)‐2‐oxoethyl)triphenylphosphonium chloride treatment during low‐Mg diet improved cardiac relaxation, increased ATP levels, and reduced
S
‐glutathionylated cMyBPC.

Conclusions
Mg deficiency caused a reversible diastolic cardiomyopathy associated with mitochondrial dysfunction and oxidative modification of cMyBPC. In deficiency states, Mg supplementation may represent a novel treatment for diastolic heart failure.
Early Contributors to Healthy Arterial Aging Versus Premature Atherosclerosis in Young Adults: The Bogalusa Heart Study
Authors: Razavi Alexander C. , Bazzano Lydia A. , He Jiang , Krousel‐Wood Marie , Chen Jing , Fernandez Camilo , Whelton Seamus P. , Kelly Tanika N. 
Published: June 2021

Background
Early identification of healthy arterial aging versus premature atherosclerosis is important for optimal atherosclerotic cardiovascular disease risk stratification and prevention. We sought to identify predictors for the long‐term absence of carotid plaque among young adults.

Methods and Results
We included 508 participants from the Bogalusa Heart Study without clinical atherosclerotic cardiovascular disease who were free of carotid plaque at baseline (2001–2002) and underwent ultrasound imaging at follow‐up (2013–2016). Modified Poisson regression estimated the persistent absence of plaque over 12.8 years. Participants were on average age 36.2 years at baseline, 64% were women, and 29% were Black. Although nearly all participants (97%) had a 10‐year atherosclerotic cardiovascular disease risk <7.5%, there were 162 people (32%) who developed premature atherosclerosis. Aside from younger age (risk ratio [RR], 1.21; 95% CI, 1.07–1.36, per 10 years) and a total cholesterol/high‐density lipoprotein cholesterol ratio <3.5 (RR, 1.15; 95% CI, 1.01–1.30), normal values of traditional risk factors did not predict long‐term absence of plaque. Independent from traditional markers including glomerular filtration rate, serum calcium‐phosphate product (RR, 1.07; 95% CI, 1.01–1.14, per 1‐SD lower), phosphate (RR, 1.15; 95% CI, 1.03–1.29, per 1 mg/dL lower), and dietary sodium <2300 mg/day (RR, 1.20; 95% CI, 1.02–1.41) were significantly associated with the non‐development of plaque.

Conclusions
Nearly one third of young adults with a low burden of traditional risk factors developed premature atherosclerosis. Beyond younger age and an ideal lipoprotein profile, lower calcium‐phosphate homeostasis and low sodium intake were associated with long‐term absence of carotid plaque. These results suggest that dietary and intrinsic minerals are early contributors to the development of arterial aging phenotypes.
Exercise‐Based Cardiac Rehabilitation and All‐Cause Mortality Among Patients With Atrial Fibrillation
Authors: Buckley Benjamin J. R. , Harrison Stephanie L. , Fazio‐Eynullayeva Elnara , Underhill Paula , Lane Deirdre A. , Thijssen Dick H. J. , Lip Gregory Y. H. 
Published: June 2021

Background
There is limited evidence of long‐term impact of exercise‐based cardiac rehabilitation (CR) on clinical end points for patients with atrial fibrillation (AF). We therefore compared 18‐month all‐cause mortality, hospitalization, stroke, and heart failure in patients with AF and an electronic medical record of exercise‐based CR to matched controls.

Methods and Results
This retrospective cohort study included patient data obtained on February 3, 2021 from a global federated health research network. Patients with AF undergoing exercise‐based CR were propensity‐score matched to patients with AF without exercise‐based CR by age, sex, race, comorbidities, cardiovascular procedures, and cardiovascular medication. We ascertained 18‐month incidence of all‐cause mortality, hospitalization, stroke, and heart failure. Of 1 366 422 patients with AF, 11 947 patients had an electronic medical record of exercise‐based CR within 6‐months of incident AF who were propensity‐score matched with 11 947 patients with AF without CR. Exercise‐based CR was associated with 68% lower odds of all‐cause mortality (odds ratio, 0.32; 95% CI, 0.29–0.35), 44% lower odds of rehospitalization (0.56; 95% CI, 0.53–0.59), and 16% lower odds of incident stroke (0.84; 95% CI, 0.72–0.99) compared with propensity‐score matched controls. No significant associations were shown for incident heart failure (0.93; 95% CI, 0.84–1.04). The beneficial association of exercise‐based CR on all‐cause mortality was independent of sex, older age, comorbidities, and AF subtype.

Conclusions
Exercise‐based CR among patients with incident AF was associated with lower odds of all‐cause mortality, rehospitalization, and incident stroke at 18‐month follow‐up, supporting the provision of exercise‐based CR for patients with AF.
Contemporary Metaphor Studies and Classical Texts
Authors: Novokhatko Anna A. 
Published: June 2021

Abstract
This article reviews recent studies on metaphor theories applied to the classical corpus and argues that approaches from cognitive linguistics are essential for the re-interpretation of Greek and Latin texts. Its main focus are two monographs, Andreas T. Zanker’s Metaphor in Homer and Tommaso Gazzarri’s Theory and Practice of Metaphors in Seneca’s Prose. The volume of collected papers on spatial metaphors in ancient texts edited by Fabian Horn and Ciliers Breytenbach proposes that the Lakoff-Johnson approach to cognitive metaphor is productive and that mappings from empirically accessible domains construct abstract concepts in spatial models of mental activity.
The Hanoi Reprint of the Precious Scroll of Incense Mountain (1772) and the Printing of Buddhist Works in Northern Vietnam at the End of the Eighteenth Century
Authors: Nguyễn Tô Lan , Berezkin Rostislav 
Published: June 2021

Abstract
The Precious Scroll of Incense Mountain is a popular Buddhist narrative in prosimetric form that was transmitted to Vietnam from China and reprinted in Hanoi with imperial sanction in 1772. The historical background of the Hanoi reprint demonstrates that this text had much higher status in Vietnam than in China. In Vietnam it was regarded as an authoritative Buddhist scripture. The case of the reprint of the Precious Scroll of Incense Mountain reveals the role of Buddhist monasteries as centers of woodblock printing in Vietnam, which still remains understudied in current research. The growth of printing of Buddhist works, which enjoyed the support of the court and officials in the seventeenth and eighteenth centuries, testifies to the popularity of Buddhism among the ruling elite during the Later Lê dynasty, when Confucianism was proclaimed the official ideology of the state.
Sandfontein: An Operational Re-examination of the Battle, Contextualised within General J.C. Smuts’ First Phase of the German South West African Campaign 1914
Authors: Katz David Brock 
Published: June 2021

AbstractThe battle of Sandfontein November 26, 1914 marked the fledgeling Union Defence Force’s first defeat. Historians have used this long-forgotten battle as a lens to view the divisive political and military aspects of the Union’s early history. Unfortunately, some of their scholarship has passed through a distorted lens. Official histories were the first to obfuscate military and leadership shortcomings and interfere with the operational context surrounding Sandfontein. Theirs was for political reasons—a mission to protect delicate reputations and mollify a divided population. Historians have erroneously assumed that General J.C. Smuts’ initial plan for the invasion of German South West Africa 1914 was modified to exclude Walvis Bay/Swakopmund’s occupation. Instead, delays in occupying Walvis Bay/Swakopmund placed theUDF’s forces at Lüderitzbucht in a precarious position. Sandfontein, a desperate attempt to distract theSchutztruppe, was an operational failure, rather than the tacticalfaux pasportrayed by historians.
Integrating the concept of cultural intelligence into health education and health promotion
Authors: Luquis Raffy R 
Published: June 2021

Objectives: Since the 1990s, cultural competence and cultural humility have been advanced across health disciplines, including health education and promotion, as approaches to use to address the health needs of increasingly diverse populations, reduce persistent health disparities and promote health and health equity. While these terms are sometimes used interchangeably, each of them represents a different approach when working across cultural groups. Health professionals, including health education specialists, may also find it helpful to employ cultural intelligence when working with diverse populations. The purpose of this article is to briefly define cultural competence and cultural humility and describe how cultural intelligence can provide health education specialists with another tool when working with diverse groups. Design: Review of the literature. Setting: USA and related contexts. Results: While cultural intelligence shares some similarities with previous terms, it differs in drawing from intelligence research and emphasises an understanding of different cultures, problem-solving and adaptations in numerous cultural settings. Conclusion: This article defines cultural intelligence as an essential capability to learn and use when engaging with diverse cultural groups and working in cross-cultural settings.
Use of generic social services and social integration of patients with a severe mental illness in Belgium: Individual and services network determinants
Authors: Grard Adeline , Nicaise Pablo , Smith Pierre , Lorant Vincent 
Published: June 2021

Background: Patients with severe mental illnesses (SMI) have low levels of social integration, which could be improved if they used social services. To our knowledge, however, the extent to which they use generic social services remains unknown. Aims: We assessed the extent to which patients with SMI use generic social services and the factors that may drive that usage. Method: In 2014, we carried out a multi-setting clustered survey of patients with severe mental disorders ( n = 1,019, participation rate = 71%) and of services ( n = 517, participation rate = 53%) in 19 networks of services, covering most of Belgium. On the one hand, we asked patients, amongst other, about their health condition, their social integration in the community, and their use of social services of different types. On the other hand, we asked each service to report on its relationships with other services in the services networks. Results: On average, patients’ use of generic social services within the previous 6 months was low (6%–16%), with the exception of administrative services. There were few differences in usage according to the severity of patients’ symptoms, but some differences according to gender and age were observed. Social integration was improved when generic social services were more central in the networks. Conclusions: We suggest that generic social services should be more central in mental health services networks.
Online digital storytelling video on promoting men’s intentions to seek counselling for depression: The role of empathy
Authors: Keum Brian TaeHyuk , Hearns Maynard , Agarwal Pritha , Nguyen Mary 
Published: June 2021

Background: Applying the narrative transportation theory, we sought to test the role of a male-sensitive digital storytelling video as a source to persuade men to develop greater intentions to seek counselling based on their empathic reactions to the storyteller. Methods: Using a post-test only design, a total of 247 diverse adult men ( M = 35.86, SD = 12.75) were randomly assigned to either the brochure or video condition and subsequently reported on their state empathy, perceived persuasiveness, and intentions to seek counselling. Controlling for previous counselling experience, a three-way interaction analysis was conducted to assess the significance of the relationship between persuasiveness and intentions to seek counselling across the two conditions, and whether empathy moderated this association in each condition. Results: For men who viewed the brochure, greater persuasiveness was linked to lower intentions to seek counselling at all levels of empathy; although, at high empathy, the relationship was not significant. A similar trend was observed for men who viewed the video at low and mean empathy levels. However, for men who reported high empathy after viewing the video, greater persuasiveness was significantly linked to greater intentions to seek counselling. Conclusion: Empathy may play a viable role in promoting intentions to seek counselling among men who view persuasive digital storytelling content on depression. However, more research needs to be conducted on the conditions that make it favourable for men to have empathic reactions to the contents. Implications for research and the potential for intervention are discussed.
Mental Health, Behavior Change Skills, and Eating Behaviors in Postpartum Women
Authors: Yu Yang , Ma Qianheng , Fernandez Isabel Diana , Groth Susan W 
Published: June 2021

Excessive postpartum weight retention conveys risks for future metabolic diseases. Eating behaviors influence postpartum weight retention; however, the modifiable predictors of eating behaviors remain unclear. Using data from a three-arm, randomized controlled trial, the purpose of this study was to examine the longitudinal associations of mental health (e.g., depressive symptoms) and behavior change skills (e.g., self-efficacy) with eating behaviors (i.e., compensatory restraint, routine restraint, emotional eating, and external eating) among women (N = 424) over 18-months postpartum. Results revealed that depressive symptoms, perceived stress, healthy eating self-efficacy, overeating self-efficacy, self-weighing, and problem-solving confidence were associated with one or more of the examined eating behaviors. Furthermore, depressive symptoms moderated the association between healthy eating self-efficacy and routine restraint. Perceived stress moderated the associations between healthy eating/overeating self-efficacy and emotional eating. The findings suggest that mental health and behavior change skills may serve as targets for interventions designed to improve postpartum women’s eating behaviors. Clinical trials registry:ClinicalTrials.gov #NCT01331564
Remote home visits: Exploring the concept and applications of remote home visits within health and social care settings
Authors: Jones Natalie Louise , Read Jennifer , Field Becky , Fegan Colette , Simpson Emma , Revitt Claire , Lanfranchi Vita , Ciranvenga Fabio 
Published: June 2021

Introduction This study consulted intended users and adopters of technology about a remote home visit application called Virtual Visit Approach. Participants were shown a video of a ‘mock’ remote home visit and asked to discuss the potential benefits, barriers and uses they could envisage. Methods Purposive sampling brought together stakeholders, patients and public representatives to capture thoughts, feelings and views in co-design workshops. Primary qualitative data were collected in real time. Post workshop, they were analysed and categorised into key themes and subthemes. Findings The opportunity to conduct remote home visits was regarded as a positive adjunct to usual practice. However, concerns about the quality of remote assessments were expressed by participants in the workshops. Conclusion The NHS response to COVID-19 sparked a national roll out of the use of video conferencing technology. The opportunity to access technology to conduct remote visits and consultations, has instigated a seismic change in the way healthcare is delivered now and for the future. However, there is much we do not yet know about the impact on the intended adopters and users of remote visits and consultations. This study demonstrated the importance of involving intended adopters and users in the co-design of technology to explore potential benefits, barriers and uses providing valuable insights to inform future design and development.
The Indonesian sociocultural contexts related to daily occupations of children with cancer during hospitalisation: The parents’ perspective
Authors: Buwana Cahya , Ito Yuko , Brintnell E Sharon 
Published: June 2021

Background The sociocultural phenomenon affecting daily occupations of hospitalised children with cancer in a diverse country like Indonesia is thought-provoking and requires exploration. Objective This study aims to explore the sociocultural contexts related to daily occupations of children with cancer during hospital admittance from the parents' perspective. Methods Semi-structured interviews were conducted with parents of children with cancer who had been hospitalised for two weeks or more. The data were collected at the paediatric ward of “Dharmais” National Cancer Center Hospital, Jakarta. The study uses interpretative phenomenological analysis (IPA). Results Nine parents of children with cancer consented to the study. Three interconnected themes emerged as necessary to the sociocultural context among participants. These involve ‘The surrounding human environment as primary encouragement’, ‘Culture and spirituality as the basic standard’ and ‘Activity adjustments as new habits’. Conclusions The themes revealed that the daily occupations of hospitalised children with cancer are strongly encouraged by family and social systems in Indonesia, spiritual aspects of the parents and the occupational changes due to the new settings.
Exploring the process of health in mothers of children with cerebral palsy: Changing “clinical reasoning”
Authors: Dehghan Leila , Dalvand Hamid , Hadian Rasanani Mohammad Reza , Kelly Greg 
Published: June 2021

Introduction The issue of the health status of mothers of children with disability is one that is beginning to be addressed more fully. This study aimed to explore the process of health in mothers during caregiving of children with cerebral palsy (CP). Method A qualitative research method with a grounded theory approach was used, including purposive and theoretical sampling. A constant comparative analysis method was adopted, and data were gathered from 15 mothers with CP children through interviews. Results The results were grouped into six main categories: Self-neglecting of their health, facing challenges in caring their children, physical and psychosocial damages, perceiving threat of health problems from concern to action, trying to regain their health, and caring in a complex context. “Facing challenges in caring” was extracted as a core concept. Conclusion Results showed an urgent need to establish family-centered services in clinical settings and change the “way of thinking” of the health provider system.
Focal superior quadrant haemorrhages in post COVID-19 patient: A target for personalized medicine
Authors: Savastano Maria Cristina , Culiersi Carola , Savastano Alfonso , Gambini Gloria , Caporossi Tomaso , Rizzo Stanislao 
Published: June 2021

Purpose: To report a case of multiple superior quadrant intraretinal haemorrhages in post-COVID-19 patient. Case description: A 58-year-old male with a history of coronary artery disease and hypertension, presented with multiple superior quadrant intraretinal haemorrhages in the superonasal quadrant of the left eye 1 month after hospitalization for COVID-19. The right eye was normal. During his 10-day stay, he was treated with hydroxychloroquine, lopinavir + ritonavir, ceftriaxone, and his pre-existing antiplatelet therapy. During hospitalization, a complete medical work up showed an anomalous increase in D-dimer. He did not require intensive care support. Conclusions: In this report, we focused on the origin of retinal bleeding in a post COVID-19 patient, likely due to a focal occlusion of a vessel. Considering the nature of SARS-CoV-2 infection, we hypothesize that retinal haemorrhages were caused by a combination of factors including the patient’s antiplatelet therapy and the thrombotic microvascular injury caused by the virus.
Māori and autism: A scoping review
Authors: Tupou Jessica , Curtis Sally , Taare-Smith Dorothy , Glasgow Ali , Waddington Hannah 
Published: June 2021

Cultural groups may vary considerably in their understandings of autism spectrum disorder and approaches to supporting autistic individuals. However, approaches to researching, identifying and managing autism are largely dominated by Western perspectives. This review provides an overview of the literature related to autism and Māori, the indigenous people of Aotearoa/New Zealand. A search of the peer-reviewed and grey literature identified 273 potentially relevant publications, and 13 of these met inclusion criteria. The included publications addressed questions related to Māori understandings of autism, Māori prevalence rates and diagnostic and support services for Māori. Findings suggest broad differences in Māori and Western understandings of autism and slightly higher autism prevalence rates for Māori than for non-Māori New Zealanders. The need for diagnostic and support services that are both effective and culturally appropriate for Māori was also highlighted. These findings are discussed in relation to implications for future research and the provision of services for autistic Māori. Lay abstract Most current approaches to identifying, researching and managing autism are based on Western views and understandings. However, different cultural groups may understand and approach autism differently. We searched a wide range of websites, academic journals and other sources for published information related to autism and Māori, the indigenous people of Aotearoa/New Zealand. Our search identified 13 publications that addressed questions related to Māori understandings of autism, Māori prevalence rates and diagnostic and support services for Māori. Overall, we found broad differences in Māori and Western understandings of autism and slightly higher autism prevalence rates for Māori than for non-Māori New Zealanders. Findings also highlighted a need for diagnostic and support services that are both effective and culturally appropriate for Māori. We discuss what these findings might mean for future research and the provision of services for Māori with autism.