bluuebunny/crossref_metadata_2025_split huggingface dataset:
TriGAN: image-to-image translation for multi-source domain adaptation
Authors: Roy Subhankar , Siarohin Aliaksandr , Sangineto Enver , Sebe Nicu , Ricci Elisa 
Published: January 2021

AbstractMost domain adaptation methods consider the problem of transferring knowledge to the target domain from a single-source dataset. However, in practical applications, we typically have access to multiple sources. In this paper we propose the first approach for multi-source domain adaptation (MSDA) based on generative adversarial networks. Our method is inspired by the observation that the appearance of a given image depends on three factors: thedomain, thestyle(characterized in terms of low-level features variations) and thecontent. For this reason, we propose to project the source image features onto a space where only the dependence from the content is kept, and then re-project this invariant representation onto the pixel space using the target domain and style. In this way, new labeled images can be generated which are used to train a final target classifier. We test our approach using common MSDA benchmarks, showing that it outperforms state-of-the-art methods.
Subjective cognitive complaints and permanent work disability: a prospective cohort study
Authors: Pihlajamäki Minna , Arola Heikki , Ahveninen Heini , Ollikainen Jyrki , Korhonen Mikko , Nummi Tapio , Uitti Jukka , Taimela Simo 
Published: January 2021

Abstract
Purpose
Work disability (WD) is a medico-legal concept that refers to disability benefits (DB) granted due to diseases. We assessed whether subjective cognitive complaints (SCC)—presenting as self-rated difficulties of concentration, memory, clear thinking, and decision making—predict permanent WD in knowledge-intensive occupations.

Methods
In this prospective cohort study with up to 7-year follow-up, we combined the SCC questionnaire results with reliable registry data on the DBs of 7161 professional/managerial employees (46% females). We excluded employees who were on long-term sickness absence (SA) or had received a DB at baseline. The exposure variable was the presence of SCC. Age and SA before the questionnaire as a proxy measure of general health were treated as confounders and the analyses were conducted by gender. The outcome variable was a granted DB. The cumulative incidence function illustrates the difference between SCC categories, and the Fine-Gray model estimates the predictors of WD during the 8-year follow-up.

Results
The annual incidence of DB was 0.15% in the entire cohort: 0.18% among the females, and 0.12% among the males (p = 0.795). The most common primary reasons for permanent WD were mental (36%) and musculoskeletal (20%) disorders. SCC predicted DB in both genders when controlling for age and prior SA. Hazard ratios were 2.9 with a 95% confidence interval 1.4–6.0 for the females and 3.7 (1.8–7.9) for the males.

Conclusion
Subjective cognitive complaints predict permanent WD in knowledge-intensive occupations. This finding has implications for supporting work ability and preventing work disability among employees with cognitively demanding tasks.
Metacognition in adult ADHD: subjective and objective perspectives on self-awareness of cognitive functioning
Authors: Butzbach Marah , Fuermaier Anselm B. M. , Aschenbrenner Steffen , Weisbrod Matthias , Tucha Lara , Tucha Oliver 
Published: January 2021

AbstractAlthough attention deficit hyperactivity disorder (ADHD) in adulthood is associated with marked cognitive impairment, research on metacognition in adult ADHD is scarce. Deficits in metacognition may have a negative impact on treatment adherence, functional outcomes, and everyday life. This study explores metacognition, specifically self-awareness of cognitive performance, in adults with ADHD by combining objective and subjective assessments. Forty-seven patients with ADHD and 47 control individuals completed a neuropsychological assessment battery including tests for attention, executive functions and memory (objective assessment), as well as questionnaires for cognitive functioning and symptom severity (subjective assessment; self- and informant-report). Participants evaluated their test performance of the objective assessment after test completion by selecting a percentile rank which was subtracted from their normed test result, yielding a discrepancy score. Compared to controls, adults with ADHD showed impairments in attention (medium effects) and memory (small and medium effects), but not in executive functions. The discrepancy scores between self-evaluation and cognitive performance revealed deficits in self-awareness of attentional functions (small effects), but not in executive functions and memory in patients with ADHD compared to controls. Discrepancy scores between self- and informant-reports of cognitive functioning revealed no significant differences. Adults with ADHD show impairments in metacognition in attentional functions, but may have intact metacognitive abilities in other domains. Patients with ADHD tend to overestimate their abilities, especially in attentional functions. Subjective and objective measures of metacognition may not correspond, highlighting the need for clinicians to not solely rely on patients’ self-report in their assessment.
Simulation of turbulent effective wakes for propellers in off-design conditions by a correction factor approach
Authors: Sánchez-Caja Antonio , Martio Jussi , Viitanen Ville M. , Siikonen Timo 
Published: January 2021

AbstractThis paper presents a procedure for the estimation of propeller effective wakes in oblique flows. It shows how a recently developed method for controlling coupling errors can be applied to analyze propellers operating in off-design conditions. The approach allows the use of fast potential flow methods for the representation of the propeller in the context of viscous flow solvers and works accurately for a wide range of advance numbers and incidence angles with a minimum computational cost. The new method makes it possible to disclose flow phenomena on the effective wake that were hidden in conventional approaches of effective wake simulation. Different application cases are analyzed, such as a propeller-shaft configuration in inclined flow, a pod propulsor in an oblique inflow, and a ship hull advancing at a yaw angle. A dipole-like distortion on the effective wake is unmasked for a uniform flow incident to a propeller mounted on an inclined shaft. The flow component perpendicular to the axis is found to be responsible for the distortion. The effect of the direction of propeller rotation on the effective wake is illustrated for a single-shaft ship moving at a yaw angle. In particular, keel vortices are either attracted to or repelled from the propeller disk depending on the sign of the yaw angle or alternatively on that of the propeller rotation.
Gender differences in patient journey to diagnosis and disease outcomes: results from the European Map of Axial Spondyloarthritis (EMAS)
Authors: Garrido-Cumbrera Marco , Poddubnyy Denis , Gossec Laure , Mahapatra Raj , Bundy Christine , Makri Souzi , Sanz-Gómez Sergio , Christen Laura , Delgado-Domínguez Carlos J. , Navarro-Compán Victoria ,   on behalf of the EMAS Working Group
Published: January 2021

Abstract
Introduction/objectives
To evaluate the journey to diagnosis, disease characteristics and burden of disease in male and female patients with axial spondyloarthritis (axSpA) across Europe.

Method
Data from 2846 unselected patients participating in the European Map of Axial Spondyloarthritis (EMAS) study through an online survey (2017–2018) across 13 countries were analysed. Sociodemographic characteristics, lifestyle, diagnosis, disease characteristics and patient-reported outcomes (PROs) [disease activity –BASDAI (0–10), spinal stiffness (3–12), functional limitations (0–54) and psychological distress (GHQ-12)] were compared between males and females using chi-square (for categorical variables) and student t (for continuous variables) tests.

Results
In total, 1100 (38.7%) males and 1746 (61.3%) females participated in the EMAS. Compared with males, females reported considerable longer diagnostic delay (6.1 ± 7.4 vs 8.2 ± 8.9 years; p < 0.001), higher number of visits to physiotherapists (34.5% vs 49.5%; p < 0.001) and to osteopaths (13.3% vs 24.4%; p < 0.001) before being diagnosed and lower frequency of HLA-B27 carriership (80.2% vs 66.7%; p < 0.001). In addition, females reported higher degree of disease activity in all BASDAI aspects and greater psychological distress through GHQ-12 (4.4 ± 4.2 vs 5.3 ± 4.1; p < 0.001), as well as a greater use of alternative therapies.

Conclusion
The patient journey to diagnosis of axSpA is much longer and arduous in females, which may be related to physician bias and lower frequency of HLA-B27 carriership. Regarding PROs, females experience higher disease activity and poorer psychological health compared with males. These results reflect specific unmet needs in females with axSpA needing particular attention.

Key Points• Healthcare professionals’ perception of axSpA as a predominantly male disease may introduce some bias during the diagnosis and management of the disease. However, evidence about male-female differences in axSpA is scarce.• EMAS results highlight how female axSpA patients report longer diagnostic delay and higher burden of the disease in a large sample of 2846 participants of 13 European countries.• Results reflect unmet needs of European female patients. Healthcare professionals should pay close attention in order to accurately diagnose and efficiently manage axSpA cases while further research should be developed on the cause of reported gender differences.
Anti-phospholipids antibodies and immune complexes in COVID-19 patients: a putative role in disease course for anti-annexin-V antibodies
Authors: Cristiano Antonio , Fortunati Valentina , Cherubini Fabio , Bernardini Sergio , Nuccetelli Marzia 
Published: January 2021

Abstract
Introduction
Besides distinctive respiratory and digestive hallmarks, COVID-19 has been recently associated with a high prevalence of pro-inflammatory and hypercoagulable states known as “COVID-19 Associated Coagulopathy” (CAC), corresponding to a worsening in patients’ conditions, whose causes are still to be elucidated. A link between anti-phospholipid antibodies (aPLs) and viral infections has long been suggested. APLs are assessed for anti-phospholipid syndrome (APS) diagnosis, characterized by thrombocytopenia, thrombosis, and coagulopathy. Furthermore, circulating immune complexes (CICs), arisen upon inflammatory responses and related immune dysregulation, can lead to endothelial cell damage and thrombotic complications.

Method
We performed an extended panel including IgG/IgM anti-cardiolipin, IgG/IgM anti-β2-glycoprotein-1, coupled with IgG/IgM anti-prothrombin, IgG/IgM anti-annexin-V on two COVID-19 patient groups (early and late infection time), and a negative control group. IgG CIC analysis followed to evaluate inflammatory status, through a possible complement system activation.

Results
Our results showed low positive case percentage in IgG/IgM anti-cardiolipin and IgG/IgM anti-β2-glycoprotein-1 assays (4.54%, 6.25%, and 4.55%; in early infection group, late infection group, and control group, respectively); few positive cases in IgG/IgM anti-prothrombin and IgG/IgM anti-annexin-V immunoassays; and no IgG CIC positivity in any patient.

Conclusions
In conclusion, our data show a low aPL prevalence, likely excluding an involvement in the pathogenesis of CAC. Interestingly, IgG/IgM anti-prothrombin and anti-annexin-V positive cases, detected in late infection group, suggest that aPLs could temporarily increase or could trigger a “COVID-19-induced-APS-like-syndrome” in predisposed patients.

Key Points•To our knowledge, anti-prothrombin (aPT) antibodies, anti-annexin-V antibodies and CICs in COVID-19 patients have not been reported in the scientific literature.•Lack of uniformity and the low percentage of aCL/aβ2GP1 positivity preclude a putative role in CAC pathogenesis.•IgG/IgM anti-prothrombin and IgG/IgM anti-annexin-V data show that distribution of positive case number increases in late infection patients, significantly in anti-annexin-V results, suggesting a possible role for these anti-phospholipid antibodies in disease course.•aPLs can arise transiently in some patients with critical illness and SARS-CoV-2 infection (disappearing in a few weeks), as well as in other genetically predisposed patients; they could trigger a “COVID-19-induced-APS-like-syndrome”.
Reform des Europäischen Stabilitätsmechanismus — eine Einordnung
Authors: Matthes Jürgen 
Published: January 2021

ZusammenfassungEnde November 2020 wurde eine Reform des Europäischen Stabilitätsmechanismus beschlossen, die nicht unterschätzt werden sollte. Im Mittelpunkt steht die Einführung einer staatlichen Letztabsicherung für den europäischen Bankenrettungsfonds ab 2022. Doch auch weitere Änderungen sind relevant und werden in diesem Beitrag eingeordnet.
Building Large-Scale Quantitative Imaging Databases with Multi-Scale Deep Reinforcement Learning: Initial Experience with Whole-Body Organ Volumetric Analyses
Authors: Winkel David J. , Breit Hanns-Christian , Weikert Thomas J. , Stieltjes Bram 
Published: January 2021

AbstractTo explore the feasibility of a fully automated workflow for whole-body volumetric analyses based on deep reinforcement learning (DRL) and to investigate the influence of contrast-phase (CP) and slice thickness (ST) on the calculated organ volume. This retrospective study included 431 multiphasic CT datasets—including three CP and two ST reconstructions for abdominal organs—totaling 10,508 organ volumes (10,344 abdominal organ volumes: liver, spleen, and kidneys, 164 lung volumes). Whole-body organ volumes were determined using multi-scale DRL for 3D anatomical landmark detection and 3D organ segmentation. Total processing time for all volumes and mean calculation time per case were recorded. Repeated measures analyses of variance (ANOVA) were conducted to test for robustness considering CP and ST. The algorithm calculated organ volumes for the liver, spleen, and right and left kidney (mean volumes in milliliter (interquartile range), portal venous CP, 5 mm ST: 1868.6 (1426.9, 2157.8), 350.19 (45.46, 395.26), 186.30 (147.05, 214.99) and 181.91 (143.22, 210.35), respectively), and for the right and left lung (2363.1 (1746.3, 2851.3) and 1950.9 (1335.2, 2414.2)). We found no statistically significant effects of the variable contrast phase or the variable slice thickness on the organ volumes. Mean computational time per case was 10 seconds. The evaluated approach, using state-of-the art DRL, enables a fast processing of substantial amounts irrespective of CP and ST, allowing building up organ-specific volumetric databases. The thus derived volumes may serve as reference for quantitative imaging follow-up.
Organizational Virtues and Organizational Anthropomorphism
Authors: Martin Felix 
Published: January 2021

AbstractAnthropomorphism is the attribution of human features to non-human subjects. Anthropomorphized organizations acquire in the minds of their members a unique identity, which becomes capable of guiding members’ motivations, with important managerial implications. Ashforth et al. (Acad Manage Revhttps://doi.org/10.5465/amr.2016.0496, 2018) offered a theoretical model of anthropomorphism in organizations, including “top-down” and “bottom-up” processes of organizational anthropomorphism as antecedents, and sensemaking and the sense of social connection of the organization as outcomes. Using SEM, this study operationalizes Ashforth et al.’s (Acad Manage Revhttps://doi.org/10.5465/amr.2016.0496, 2018) model using a two-trait scale of organizational virtue (Empathy and Courage) derived from Chun (J Bus Ethics 57:269–284, 2005), including measures of CSR and OCB as antecedents, and organizational justice and affective commitment as outcomes. The model is tested on survey data from seven UK managed service organizations in the hotels, logistics and legal sectors. As secondary contribution, moderation analysis is undertaken by industry, offering further insight into the evaluation of organizational anthropomorphism. Firstly, we note that high evaluations of Empathy influence evaluations of Courage through a halo effect. Secondly, we note that heuristic evaluation of the firm’s CSR practice also influences perceptions of Empathy and Courage. The paper also includes a discussion of the critique of organizational virtues by virtue ethicists in an effort to advance the dialogue between the two traditions.
Selective Mutism and Its Relations to Social Anxiety Disorder and Autism Spectrum Disorder
Authors: Muris Peter , Ollendick Thomas H. 
Published: January 2021

AbstractIn current classification systems, selective mutism (SM) is included in the broad anxiety disorders category. Indeed, there is abundant evidence showing that anxiety, and social anxiety in particular, is a prominent feature of SM. In this article, we point out that autism spectrum problems in addition to anxiety problems are sometimes also implicated in SM. To build our case, we summarize evidence showing that SM, social anxiety disorder (SAD), and autism spectrum disorder (ASD) are allied clinical conditions and share communalities in the realm of social difficulties. Following this, we address the role of a prototypical class of ASD symptoms, restricted and repetitive behaviors and interests (RRBIs), which are hypothesized to play a special role in the preservation and exacerbation of social difficulties. We then substantiate our point that SM is sometimes more than an anxiety disorder by addressing its special link with ASD in more detail. Finally, we close by noting that the possible involvement of ASD in SM has a number of consequences for clinical practice with regard to its classification, assessment, and treatment of children with SM and highlight a number of directions for future research.
Using advanced statistical tools to assess the impact of a small landfill site on the aquatic environment
Authors: Przydatek Grzegorz 
Published: January 2021

AbstractThe aim of the study was to assess the impact of a small municipal landfill on the aquatic environment over 9 years, using advanced statistical tools. The results of the study of surface, ground- and leachate waters from 2008 to 2016 were subjected to detailed statistical analysis based on 15 physicochemical indicators. Factor analysis accounted for the requirements of the WHO, the European Union and the nation of Poland using 8 statistical analytical methods. The analysis of leachate contamination from the landfill site with the use of advanced statistical tools revealed its interaction with groundwater. The assessment was based on increased and statistically significant values and correlations of temperature, Zn and N–NO3between leachate and groundwater, factors demonstrating the negative impact of the landfill. In the case of Zn, there was also a correlation between the tested waters below the landfill. The increased PAH values in the examined surface and ground waters were not a consequence of waste disposal. However, the deterioration of the chemical state of groundwater in the vicinity of the landfill could result from a certain dysfunction of the facility’s infrastructure after operating for more than 20 years.
Additive main effects and multiplicative interaction analyses of yield performance in rice genotypes for general and specific adaptation to salt stress in locations in India
Authors: Krishnamurthy S. L. , Sharma P. C. , Sharma D. K. , Singh Y. P. , Mishra V. K. , Burman D. , Maji B. , Mandal S. , Sarangi S. K. , Gautam R. K. , Singh P. K. , Manohara K. K. , Marandi B. C. , Chattopadhyay K. , Padmavathi G. , Vanve P. B. , Patil K. D. , Thirumeni S. , Verma O. P. , Khan A. H. , Tiwari S. , Geetha S. , Gill R. , Yadav V. K. , Roy B. , Prakash M. , Anandan A. , Bonifacio J. , Ismail A. M. , Singh R. K. 
Published: January 2021

AbstractThe aim of this study was to identify stable rice genotypes tolerant to a salt stress environment and to identify ideal mega-environments using AMMI (additive main effects and multiplicative interaction) stability model analysis. A total of 13 rice genotypes and three salt tolerance checks were evaluated across 13 salt stress locations (alkaline and saline) for the two kharif seasons of 2014 and 2015. Genotype CSR 36 (CHK3) was found to be the most ideal of those tested. Genotypes CHK2 (CST 27) and IR 87952-1-1-1-2-3-B (G05) were found to be the most stable, with above average yields. The check CSR 36 (CHK3) genotype was the best performer in the majority of the environments studied, followed by CSR 27 (CHK2) and IR 87952-1-1-1-2-3-B (G05) which were the best genotypes in the mega-environment consisting of 21 environments evaluated across stress locations and year combinations. Overall, the most promising genotype (IR 87952-1-1-1-2-3-B) had high mean yield and stability and could be used for commercial cultivation or used as donor for breeding programs across salt-affected soils. The genotypes GN13 (IR 87938-1-1-2-1-3-B) and GN11 (IR 87938-1-2-2-1-3-B) showed 60–80% yield advantage at specific salt stress locations, showing that these genotypes could be used for specific environments of salt-affected soils in India.
Pigou in the 21st Century: a tribute on the occasion of the 100th anniversary of the publication of The Economics of Welfare
Authors: Edenhofer Ottmar , Franks Max , Kalkuhl Matthias 
Published: January 2021

AbstractThe year 2020 marks the centennial of the publication of Arthur Cecil Pigou’s magnum opusThe Economics of Welfare. Pigou’s pricing principles have had an enduring influence on the academic debate, with a widespread consensus having emerged among economists that Pigouvian taxes or subsidies are theoretically desirable, but politically infeasible. In this article, we revisit Pigou’s contribution and argue that this consensus is somewhat spurious, particularly in two ways: (1) Economists are too quick to ignore the theoretical problems and subtleties that Pigouvian pricing still faces; (2) The wholesale skepticism concerning the political viability of Pigouvian pricing is at odds with its recent practical achievements. These two points are made by, first, outlining the theoretical and political challenges that include uncertainty about the social cost of carbon, the unclear relationship between the cost–benefit and cost-effectiveness approaches, distributional concerns, fragmented ministerial responsibilities, an unstable tax base, commitment problems, lack of acceptance and trust between government and citizens as well as incomplete international cooperation. Secondly, we discuss the recent political success of Pigouvian pricing, as evidenced by the German government’s 2019 climate policy reform and the EU’s Green Deal. We conclude by presenting a research agenda for addressing the remaining barriers that need to be overcome to make Pigouvian pricing a common political practice.