bluuebunny/crossref_metadata_2025_split huggingface dataset:
Specialised Coating Processes Finding Pharmaceutical Applicability
Authors: Saikh Mahammed Athar Alli , Mohapatra Prithwiraj 
Published: November 2021

The manuscript aims at furnishing comprehensive information pertaining specialised coating technology/ processes. Solid dosage forms and solid particulates (SDFSP) are the major contributing group in the solid pharmaceuticals (SoPs). SDFSP exhibit peculiar physico-chemical properties and interaction behaviour which create problems/ issues during their handling, processing, storage, and use. Modifying and/or engineering surface attributes of SDFSP are advocated as powerful tool to modify their interaction behaviour and realise their worthy applications and functionalities. In this regard coating their surfaces with coating material (CM) is novel approach. Said approach involves wet and dry process for realising deposition of CM onto the surface of SDFSP substrates. Both the processes modify and/or alter innate properties of SDFSP substrates either physically or chemically. Basing on involved wet or dry process the coating method is either dry coating method (DCM) or wet coating method (WCM). Accordingly nowadays there available number of specialised devices, that bases on diverse technologies. Amongst them some involves state-of-art process/ technology like Supercell coating technology (SCT), Chemical vapour deposition (CVD), Atomic/molecular layer deposition (AMLD), Electrostatic deposition, Thermo-mechanical process, Resonant acoustic technology, Fluidised-bed process, Supercritical fluid (SCF) technology, and others. These foundational for commercially availability of specialised equipments like Magnetically Assisted Impaction Coater (MAIC), Resodyn acoustic mixer, Hybridizer®, Theta-composer®. Mechanofusion®, and others. Working and working principle, applicability, benefits, pros and limitations of specialised coating processes and technologies are herein discussed and presented. Contained information hoped to be beneficent for pharmaceutical professionals and technocrats and professionals of allied field.
Keywords: Coating, composite product, modification, specialised, surface.
Tapentadol: Use and Abuse
Authors: Juvin Thomas CV , Sambathkumar R , Venkateswaramurthy N 
Published: November 2021

Tapentadol is a synthetic opioid analgesic that has been on the market in India since 2011. According to international studies, there is a low danger of abuse and diversion. Prescription opioid pain reliever abuse remains a major public health concern. Tapentadol, a prescription painkiller, differs from opioids such as oxycodone and morphine in that it has two modes of action: opioid receptor agonism and norepinephrine reuptake inhibition. Tapentadol has been on the market in India for eight and a half years. Our center was the topic of a single peer-reviewed research in 2017 that detailed two instances of abuse. Tapentadol is less likely to be diverted, abused, addicted, overdosed, or sold on the street than other prescribed opioids. This article reviews uses, pharmacological properties and abuse of tapentadol as it is the most serious issues like addiction, seeking behavior, withdrawal, and physical dependency .The main challenge with tapentadol use is controlling the ratio of MOR agonist to NRI. Finally, tapentadol provides both nociceptive and neuropathic pain relief, but there are concerns about abuse and reliance.
Keywords: Tapentadol, Abuse, Opioid, Addiction.
Konsep Pendidikan Profesional Perspektif Undang-Undang tentang Guru dan Dosen
Authors: Sutarsih Eti , Misbah M 
Published: November 2021

Abstract

Educators must have an attitude in dealing with students so that they are in accordance with the teachings conveyed by Islam. Educators need to know and be aware of the profession that is taken as a calling for the soul to be able to achieve a maximum learning goal, they need to know and practice several tasks as professional educators. Professional educators are regulated in the Law on Teachers and Lecturers. Therefore, it is important for an educator to learn and implement it to become a professional educator. This research uses descriptive analysis method. This type of research is carried out on national and international literature review sources related to the concept of professional educators. Professional educators must carry out their duties as educators as stated in the law on teachers and lecturers. Professional educators must have educator competencies in carrying out their responsibilities in educating, teaching, guiding, assessing, training, and evaluating students. In addition, the quality of an educator will continue to improve, which in the end, the quality of educational institutions will also have quality. Professional educators will continue to strive to develop themselves according to the times. Has the nature and character that is in accordance with the duties or obligations as an educator

Keywords

Educators, Professional, and Law

Abstrak

Pendidik harus memiliki sikap dalam menangani peserta didik agar sesuai dengan ajaran yang disampaikan oleh agama Islam. Pendidik perlu mengetahui dan sadar akan profesi yang diambil sebagai panggilan jiwa untuk dapat mencapai sebuah tujuan pembelajaran yang maksimal perlu mengetahui dan mengamalkan beberapa tugas sebagai pendidik professional. Pendidik profesional sudah diatur dalam Undang-Undang tentang Guru dan Dosen. Oleh karena itu, pentingnya seorang pendidik mempelajari dan melaksanakan untuk menjadi pendidik yang profesional. Penelitian ini menggunakan metode analisis deksriptif. Jenis penelitian yang dilakukan pada sumber-sumber kajian pustaka nasional maupun internasional yang berhubungan dengan konsep pendidik profesional. Pendidik profesional harus menjalankan tugas sebagai pendidik yang telah tercantum di dalam undang-undang tentang guru dan dosen. Pendidik profesional harus memiliki kompetensi-kompetensi pendidik dalam menjalankan tanggung jawab dalam mendidik, mengajar, membimbing, menilai, melatih serta mengevaluasi peserta didik. Selain itu, kualitas yang dimiliki seorang pendidik akan terus meningkat yang pada akhirnya kualitas lembaga pendidikan juga akan ikut bekualitas. Pendidik profesional akan terus berusaha untuk mengembangkan diri sesuai dengan perkembangan zaman. Memiliki sifat dan karakter yang sesuai dengan tugas atau kewajiban sebagai pendidik.

Kata Kunci

Pendidik, Profesional, dan Undang-Undang
Peran Pustakawan dalam Pendampingan Penggunaan Media Sosial Terhadap Perilaku Remaja di Masyarakat
Authors: Mustar Maniso 
Published: November 2021

Introduction. Information and communication technology develops very rapidly. Without exception, social media thrives in all circles including teenagers. Social media gives benefits in life and able to provide positive impacts in economic, social and cultural. However, in the midst of the widespread use of social media, sometimes users are not aware of the negative impacts such as social media influences towards teenagers behaviours. This article aims to assist teenagers in controlling behavior due to the influence of social media in society.
Methodology. This research use descriptive method. Data collection and analysis was done with literature review from various references.
Results and Discussion. This research show that social media influences teenagersâ€™ behavior by bridging activites and friendship which may bring positive and negative impacts. Librarians may have roles in social media by giving positive values through providing constructive information which has value economically, culturally and socially among teenagers and wider community.
Conclusion. Librarians can help the community by giving accompaniment in social media usage and shaping teenagers characters through attitudes, patriotic behavior, upholding democracy and towards civil society that applies knowledge responsibly towards humanity through planned programs.
Клинический случай длительной гипоосмии после перенесенной короновирусной инфекции
Authors: Дума Светлана 
Published: November 2021

Эффективное лечение длительной гипосмии ( более 4-х месяцев) после перенесенной
короновирусной инфекции.До сих пор только предполагается, что длительно
сохраняющаяся гипо и аносмия (более 15–20 дней) обусловлена возможным поражением
непосредственно обонятельных рецепторных клеток, естественный период
восстановления которых может затянуться до 2 месяцев.
Также не следует недооценивать значимость обоняния для пациента, так как
хемосенсорная дисфункция не только снижает качество жизни, но и может привести к
тяжелым неврологическим и нейропсихиатрическим осложнениям (например, к
депрессии, когнитивным нарушениям и др.).
The influence of exogenous gibberellic acid (GA3) and 24-epibrassinolide (24-EpiBL) on seed germination and the expression of genes involved in GA and BR synthesis/signalling in pepper (Capsicum annuum L.)
Authors: Çayan Selin , Sarıkamış Gölge , Yüksel Özmen Canan , Kibar Umut , Özden Eren , Ergül Ali 
Published: November 2021

Gibberellins (GAs) and brassinosteroids (BRs) are the plant hormones involved in various physiological processes including seed germination. In this study, the effects of exogenous gibberellic acid (GA3) and 24-epibrassinolide (24-EpiBL) treatments on the expression of key genes involved in GA and BR syntheis/signalling during seed germination were investigated in pepper (Capsicum annuum L).
The expressions of BES1 and BRI1 involved in BR synthesis/signalling pathway as well as GA3OX1 and GA20OX1 associated with gibberellic acid biosynthesis in plants were determined. Exogenous GA3 treatments increased BES1 expression and the highest increase was determined with 10⁻⁸ M BR + 100 µM GA3 (P<0.05). On the contrary, the expression of BRI1 gene was significantly decreased by 10-8 M BR + 100 µM GA3 (P<0.05). The expression of GA3OX1 gene was induced with BR and GA3 treatments (P<0.05). GA20OX1 gene expression was generally higher compared to the expression of GA3OX1 and significantly increased by the GA3 treatments. Our findings are expected to bring an insight to the influence of BRs during seed germination together with the expression of associated genes.
Damage Control in Orthopedics and Traumatology
Authors: Martínez-Rondanelli Alfredo , Gomez-Sierra Maria Antonia , Ossa Arley Alberto , Hernández Rubén Darío , Torres Mauricio 
Published: November 2021

In Orthopedics, damage control is indicated in patients with pelvic and / or long bone fractures associated with unstable general conditions. Given the severity of the trauma associated with hemodynamic instability, it is not appropriate to perform a complex definitive reduction and fixation surgery for all the patient’s fractures. In these cases, its recommended to perform minimally invasive procedures which provide provisional stabilization of the fractures, this reduces pain, controls bleeding from fractures, allows for proper alignment of fractured bones and reduces dislocations, these procedures aim to control the damage of the first hit to reduce complications. Closed or open fractures of the long bones of the femur, tibia, humerus, and pelvis can lead to instability and shock making damage control in orthopedics a priority. If the patient is hemodynamically stable its recommended to stabilize all fractures with an early permanent internal fixation thereby controlling the damage with less hospitalization time. As a result, there’s a reduction in the time spent in intensive care as well as the need for mechanical ventilation, transfusions and complications. The concept of damage control as the treatment in orthopedic injuries should be individualized according to the general conditions of each patient and the severity of injuries such as open fractures, dislocations, complete dislocation of sacroiliac joint, vascular lesions, amongst others, as these lesions must be a priority in most patients with multiple injuries. This is to avoid complication and that can leave permanent sequalae’s by receiving inadequate initial treatment.
Knowledge, attitude, and prevention of self-medication practices among the general population of Gujarat
Authors: Shah Hital , Arora Bhoomi 
Published: November 2021

Objectives:
The practice of self-medication (SM) without consulting a health-care professional among the populace of both developed and developing countries like India may lead to a delay in therapeutic effectiveness. The present study was conducted to assess the knowledge, attitude, and practice of SM among the general population of Gujarat.

Material and Methods:
An observational, cross-sectional questionnaire-based study was conducted among 488 participants between April 2021 and May 2021 to evaluate the several aspects of SM. In April 2021, this study was conducted on both the genders of 18–80 years of urban and rural areas of Gujarat. Data were analyzed for descriptive statistics. The data presented in the form of percentages using tables and figures. The responses were collected and analyzed using GraphPad v.8 and Microsoft Excel for percentage and statistical significance.

Results:
Prevalence of SM was 78.3%. It was found to be practiced more among the younger age group (55.32%) than the older. Graduates practiced SM more than the others (P < 0.004). Significant association was found between its practice and residency (P < 0.03), marital status (P < 0.003), education (P < 0.004), and occupation (P < 0.0007). Fever, cough, and cold were the most common conditions noted for SM practice followed by headache. It was noticed that 63.5% participants were procured medications from pharmacy. Multivitamins, nonsteroidal anti-inflammatory drugs, and antibiotics were the most frequent medications used by participants.

Conclusion:
The prevalence of SM is alarming which causes serious health issues and needs an intervention. Planning of health awareness programs, educating people, and pharmacists are necessary for promoting rational use of medication.
3D Natural State Modeling of Mount Iyang-Argopuro Geothermal Area, East Java, Indonesia
Authors: Asmorowati Dewi , Lukmana Allen Haryanto , Prasetyo Rizqi Mahfudz 
Published: November 2021

Mount Iyang-Argopuro is one of the geothermal working areas in the East Java. Mount Iyang-Argopuro has the potential of 185 MWe of reserves and 110 MWe of resources. It is estimated to have a liquid dominated reservoir with temperature up to 250-275 oC. An early 3D natural state numerical model of Mount Iyang-Argopuro Field is created using TOUGH2 simulator in order to identify the undisturbed condition of reservoir and resource assessment. Since Mount Iyang-Argopuro geothermal area is still in the exploration stage, the model created based on based on geological, geophysical, and geochemical data. The model has an area 14 km x 8.2 km and 9180 m in thickness. The model consists of 7410 of rectangular cell blocks with the roughest cell size is 1000 m x 1000 m and the finest is 200 m x 500 m. The model is verified by matching the model temperature and pressure profiles to the calculated geothermometer temperature and pressure, which shows good match enough.
The Geomorphological Factors and Its Implications for The Tidal Energy Installations in Java, Indonesia
Authors: Kurnianto Fahmi Arif , Ikhsan Fahrudi Ahwan , Apriyanto Bejo , Nurdin Elan Artono , Fadilah Tyas Nisa 
Published: November 2021

This study aims to place the tidal energy installation effectively in Indonesia based on geomorphological factors. The survey method was used to analyze the characteristics of beaches in Indonesia. Mathematical physics model was implemented to find the new formulas based on geomorphological factors. Tides are the result of gravitational attraction and the centrifugal effect, which is the drive In the earth-moon system, tidal generating forces are the resultant forces that cause tides, namely: the earth-moon system (FS) centrifugal force and the moon's gravitational force (FB). FS works in the center of the mass of the earth-moon system whose mass point is located on the 3/4 radius of the earth. The style of tidal generator caused by the moon can be calculated by combining Newton's universal gravitational law .The results of this study consist of F = m ac, where the style of the tidal generator caused by the moon can be calculated by combining newton's universal gravitational law in equation and newton's second law of motion in Equation. The another results is tan = , where the formula takes into account constants (K) based on slopes. The last result is the constants (K) for each land form starting on 0,00 untill 1,00. The north coast of Java is more suitable for tidal energy installations because the land form is dominated by alluvium plains of the quaternary age with a lower risk than the southern region of Java. The effectiveness of tidal energy installation depends on the characteristics of the land form. In alluvial plains, the quaternary age of the alluvial plains is more suitable than the hill form volcanic quaternary, tertiary volcanic, and tertiary holokarst.
Comparison of Granitoid Characteristics West Kalimantan and Karangsambung Based On Mineralogical And Geochemical Aspects
Authors: Adi Nugroho Kevin Setyo , Setiawan Iwan , Winarno Tri 
Published: November 2021

Indonesia was included in the ring of fire so that it has various types of tectonic products, one of which is granitoid. Granitoid is very complex rock and many are found in Indonesia. Some of them are found in West Kalimantan and Karangsambung. Basis of the reasearch is there is no research that compares granitoid in two regions. The purpose of this study was to compare rock characteristics and granite petrogenesis of West Kalimantan and Karangsambung. The research method used was collecting data on field, also laboratory analysis of rock samples using a polarization microscope, refraction microscope, and X-Ray Fluorescence analysis. The mineralogical characteristics of each study area tend to be almost the same. The predominant composition of the main minerals is quartz, plagioclase and orthoclase. But specifically the rock samples from West Kalimantan have been altered from phylic-silicification-propylitic. The entire study area contained accessory minerals, namely apatite, zircon, titanite, and for monazite only in the West Kalimantan sample. There was mineralization up to the supergene stage in the presence of the characteristic minerals for the supergene covelite and chalcocytes in the West Kalimantan sample. Geochemical analysis of both regions shows the same magma affinity, namely Calc Alkaline - High K Calc Alkaline. For West Kalimantan, the value of A / CNK <1.1 has a type metaluminious and > 1.1 a type peraluminious. Meanwhile, Karangsambung A / CNK value <1.1 has a type metaluminious. So that West Kalimantan granite has two I-type and S-type. While Karangsambung is I-type. West Kalimantan granite is formed in continental arc granite (CAG) and continental collision granite (CCG). Meanwhile, Karangsambung in Volcanic Arc Granite (VAG). It can be concluded that the granites of the two regions have quite different characteristics even though they belong to a relatively similar tectonic environment.
PISA in Finland: An Education Miracle or an Obstacle to Change?
Authors: Sahlberg Pasi 
Published: November 2021

The present article discusses the role and impact of the Programme for International Student Assessment (PISA) in Finland. PISA has created a new geography of education policies and reforms by shifting global interest away from Anglo-Saxon education systems to Asian countries, as well as to Finland and Canada in the West. The article describes how PISA has become evidence of the successful education reforms in Finland carried out since the 1970s, but at the same time has created a situation where the continuous renewal of the Finnish education system has become more difficult than before. The conclusion is that PISA is animportant global benchmarking instrument, but that policy makers and the media need to make better use of the rich data that have been collected together with information about students’ academic performance.
Adapting and Designing Spaces: Children and their Schools
Authors: Kenkmann Andrea 
Published: November 2021

In schools, children experience their environment on three different levels: firstly, they constantly make spatial decisions by positioning themselves in relation to others and organising their immediate environment; secondly, they can potentially contribute to shaping the classroom spaces; and, thirdly, they are confronted with the designed school as a whole.It is argued here that our experiences of spaces are related to our memories, which provide us with a framework of references that allows us to ‘read’ and construct spaces. Whereas on the lowest level of spatial involvement children are natural decision makers, the higher levels require access to, and an understanding of, shared practices and discourses. Although existing data on children’s perceptions of their schools suggest that children’s participation inthe school design process is laudable for all sorts of reasons, such participation means overcoming considerable barriers for comparatively little gain in terms of the design quality. It is the level of the classroom where a more genuine shared organisation and (re)creation of space can take place on an everyday basis.
Variations in Primary Teachers’ Responses and Development during Three Major Science In- Service Programmes
Authors: Jarvis Tina , Pell Anthony , Hingley Philip 
Published: November 2021

This paper reports on how different types of teachers responded to in-service aimed at developing investigative-based science education (IBSE) in primary schools, and the extent to which they applied their new skills in the classroom. Common items from evaluation questionnaires allowed data to be combined from three major in-service programmes. Using complete data sets from 120 teachers, cluster analysis enabled three teacher types to be identified: a small group of ‘science unsures’, with low attitude scores and little confidence, who showed no response to the innovation; ‘holistic improvers’, who showed the largest improvement in science teaching confidence; and ‘high level, positive progressives’, who were very positive to science teaching throughout and showed gains in confidence in teachingphysics and chemistry, as well as in demonstrating the relevance of science to their pupils. Taking account of these teacher types alongside interviews and observations, nine developmental stages in how teachers apply their new expertise in the classroom and the whole school are suggested. Major factors influencing application in the classroom are the teachers’ initial science knowledge and pedagogical expertise, and motivating feedback to teachers when pupils responded positively to the innovation. Assessing teachers’ initial level of subject knowledge and science pedagogical expertise to inform the approach and amount of in-service provision is important. Subsequent mentoring as well as support from the school principal when teachers first try IBSE with pupils promotes successful implementationin the classroom.
Encouraging Teachers’ and Students’ Innovation with the Support of Teacher Learning Communities
Authors: García Leonor Margalef 
Published: November 2021

The purpose of this paper is to share knowledge generated through the implementation of “Teaching Innovation Teams” as a strategy for teachers’ professional development and innovation at the University of Alcala (Spain). We analyse the contributions of this strategy to the facilitation of curriculum innovation in higher education and reflect on some of theachievements and results of the activities carried out by these teams, identifying the dilemmas and difficulties that teachers experienced and that hinder the development of curriculum innovations. Finally, we outline some educational contributions of Teaching Innovation Teams understood as a collaborative and formative strategy to facilitate educational change.