bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modeling of Fluid Flow in a Flexible Vessel with Elastic Walls
Authors: Kozlov Vladimir , Nazarov Sergei , Zavorokhin German 
Published: July 2021

AbstractWe exploit a two-dimensional model (Ghosh et al. in Q J Mech Appl Math 71(3):349–367, 2018; Kozlov and Nazarov in Dokl Phys 56(11):560–566, 2011, J Math Sci 207(2):249–269, 2015) describing the elastic behavior of the wall of a flexible blood vessel which takes interaction with surrounding muscle tissue and the 3D fluid flow into account. We study time periodic flows in an infinite cylinder with such intricate boundary conditions. The main result is that solutions of this problem do not depend on the period and they are nothing else but the time independent Poiseuille flow. Similar solutions of the Stokes equations for the rigid wall (the no-slip boundary condition) depend on the period and their profile depends on time.
Epidemiologische Ansätze zur Klärung wichtiger Forschungsfragen zu COVID-19 – eine Übersicht
Authors: Zeeb Hajo , Ahrens Wolfgang , Haug Ulrike , Grabenhenrich Linus , Pigeot Iris 
Published: July 2021

ZusammenfassungDie Epidemiologie als wissenschaftliche Disziplin ist prädestiniert dafür, Kernfragen der COVID-19-Pandemie zu bearbeiten. Hierzu werden klassische und neue Methoden eingesetzt, es stellen sich jedoch auch neue Herausforderungen.Der Beitrag bezieht sich auf die verschiedenen Phasen des bevölkerungsbezogenen Verlaufs der SARS-CoV-2-Infektion und COVID-19-Erkrankung. Basierend auf einer selektiven Literaturrecherche werden Beispielfragestellungen anhand von in Deutschland und international durchgeführten Studien vorgestellt und die jeweiligen epidemiologischen Ansätze diskutiert, aber auch Forschungslücken beschrieben.Wissenschaftliche Fragen, die mit epidemiologischen Daten und Forschungsansätzen zu beantworten sind, stellen sich in jeder Phase des Infektions- und Krankheitsgeschehens. Beschreibende Daten werden vielfach über (wiederholte) Querschnittsstudien generiert. Für analytische Fragestellungen etwa zur Identifikation von Risikogruppen hätten besonders in der frühen Phase der Pandemie Fallkontrollstudien wertvolle Ergebnisse liefern können, wurden aber selten durchgeführt. Daten der Krankenkassen kommt eine wichtige Funktion in der Analyse von Verläufen zu; das Potenzial dieser Datenquelle in Bezug auf Fragestellungen zur Impfung kann jedoch vermutlich kaum genutzt werden. Eine verbesserte Koordination der diversen Studien sowie eine stärker auf frei zugängliche Daten (Open Data) ausgerichtete Forschungsinfrastruktur können den Beitrag der Epidemiologie zur Kontrolle dieser und zukünftiger Pandemien weiter stärken.
The influence of pain catastrophizing and central sensitization on the reported pain after hip arthroscopy
Authors: Bech Niels H. , Sierevelt Inger N. , de Rooij Aleid , Kerkhoffs Gino M. M. J. , Haverkamp Daniel 
Published: July 2021

Abstract
Purpose
This study was conducted to investigate whether the pain catastrophizing scale (PCS) and the central sensitization inventory (CSI) are predictive factors for the reported pain after hip arthroscopy.

Methods
A total of 37 patients undergoing hip arthroscopy for femoroacetabular impingement syndrome and labral tears were prospectively enrolled. All patients completed the PCS and CSI before hip arthroscopy. Postoperative pain was measured with the numeric rating scale (NRS) weekly the first 12 weeks after surgery by electronic diary.

Results
At baseline, univariate analyses showed that both the CSI and PCS were significantly associated with the NRS outcome (p < 0.01). During 12 weeks follow-up, a significant decrease on the NRS was observed (p < 0.01). Univariate analyses showed that both the CSI and PCS were significantly associated with the NRS during follow-up. Multivariate mixed model analysis showed that only the PCS remained significantly associated with the NRS outcome with a ß of 0.07 (95% CI 0.03–0.11, p < 0.01).

Conclusion
Results indicate that both the PCS and CSI are associated with the reported postoperative pain after hip arthroscopy. The PCS and CSI may be useful in daily practice to identify patients that possibly benefit from pain catastrophizing reduction therapy (e.g. counseling) prior to surgery.

Level of evidence
IV
The autonomic cardiac nervous system and arrhythmogenesis: risk stratification in the foreseeable future
Authors: Huikuri Heikki 
Published: July 2021

AbstractBoth experimental and clinical studies have shown that the autonomic nervous system plays an important role in arrhythmogenesis. Many methods describing cardiovascular autonomic regulation have been developed and tested for use as predictors of arrhythmic and other cardiovascular events. The majority of studies have focused on patients with known cardiac disease, such as prior myocardial infarction or congestive heart failure. All-cause mortality, as well as non-sudden and sudden cardiac death have been used as main endpoints. Sudden cardiac death has often been considered to be equivalent to arrhythmic cardiac arrest. Despite promising results in this field, markers of the autonomic nervous system are still not routinely used in clinical practice, mainly due to the fact that measurement of these markers does not result in evidence-based therapeutic implications. There is still a lack of randomized trials using autonomic markers as pre-defined variables in selecting patients for the studies, which would have yielded results that an intervention reduces the arrhythmic or other endpoint in those with abnormal or impaired autonomic regulation. Hence, at present, the possible use of autonomic assessment in predicting life-threatening arrhythmias is restricted to individual cases at the borders of intervention guidelines.
Remote hydroacoustic-infrasonic detection and characterization of Anak Krakatau eruptive activity leading to, during, and following the December 2018 flank collapse and tsunami
Authors: Rose Kaelynn M. , Matoza Robin S. 
Published: July 2021

AbstractA climactic eruption phase on December 22, 2018, triggered the collapse of the southwest flank and summit of Anak Krakatau stratovolcano, generating a tsunami which struck the coastlines of Sumatra and Java. We employ a selection of remote moored hydroacoustic (H08S, 3307 km; H01W, 3720 km) and infrasonic (IS06, 1156 km; IS07, 3475 km; IS52, 3638 km) stations of the International Monitoring System (IMS) to investigate eruptive activity preceding, during, and after the climactic eruption phase. We observe 6 months of co-eruptive intermittent infrasound at IS06 and powerful infrasound from the climactic eruption on IS06 and IS52. The climactic eruption phase was not detected hydroacoustically, but we observe a ~ 12-day swarm of hydroacoustic signals beginning 24 days before the flank collapse event that we attribute to sustained submarine eruptive activity at Anak Krakatau. We perform hydroacoustic waveform and envelope multiplet analysis to assess event similarity during the hydroacoustic swarm. Hydroacoustic waveforms are not well-correlated, but envelopes with a main pulse duration of ~ 20-s are correlated, with 88.7% of 247 events grouping into two multiplets using a threshold correlation coefficient of 0.75. The repetitive envelopes indicate a repetitive impulsive volcanic process, either underwater submarine explosions or volcanic earthquakes in the solid Earth coupled to the water column from the Sunda Shelf. This study further underscores the potential of remote acoustic technology for detecting and characterizing eruptions at submarine or partially submerged volcanoes.
Financial toxicity in sarcoma patients and survivors in Germany: results from the multicenter PROSa study
Authors: Büttner Matthias , Singer Susanne , Hentschel Leopold , Richter Stephan , Hohenberger Peter , Kasper Bernd , Andreou Dimosthenis , Pink Daniel , Taylor Kathy , Arndt Karin , Bornhäuser Martin , Schmitt Jochen , Schuler Markus K. , Eichler Martin 
Published: July 2021

Abstract
Purpose
Cancer patients have been shown to frequently suffer from financial burden before, during, and after treatment. However, the financial toxicity of patients with sarcoma has seldom been assessed. Therefore, the aim of this study was to evaluate whether financial toxicity is a problem for sarcoma patients in Germany and identify associated risk factors.

Methods
Patients for this analysis were obtained from a multicenter prospective cohort study conducted in Germany. Using the financial difficulties scale of the EORTC QLQ-C30, financial toxicity was considered to be present if the score exceeded a pre-defined threshold for clinical importance. Comparisons to an age- and sex-matched norm population were performed. A multivariate logistic regression using stepwise backward selection was used to identify factors associated with financial toxicity.

Results
We included 1103 sarcoma patients treated in 39 centers and clinics; 498 (44.7%) patients reported financial toxicity. Sarcoma patients had 2.5 times the odds of reporting financial difficulties compared to an age- and sex-matched norm population. Patient age < 40 and > 52.5 years, higher education status, higher income, and disease progression (compared to patients with complete remission) were associated with lower odds of reporting financial toxicity. Receiving a disability pension, being currently on sick leave, and having a disability pass were statistically significantly associated with higher odds of reporting financial toxicity.

Conclusion
Financial toxicity is present in about half of German sarcoma patients, making it a relevant quality of life topic for patients and decision-makers.
Mass occurrence and habitat selection of Common Redpolls (Carduelis flammea) after a large seed crop year: snow-covered ground facilitates food access
Authors: Dale Svein 
Published: July 2021

AbstractIn boreal forests, food supplies typically have cyclic variations, and many species here fluctuate in numbers from year to year. One group of species showing large variations in population size is birds specialized on seeds from masting trees. Here, I analyze spatial patterns of a mass occurrence and habitat selection of the Common Redpoll (Carduelis flammea) during the breeding season in southeastern Norway in 2020 after a year with large seed crops from Norway Spruce (Picea abies) and Downy Birch (Betula pubescens). I found that Common Redpoll numbers increased with elevation and towards the northwest. Numbers were also strongly and positively correlated with snow depth in early April when snow was present mainly above 400 m elevation. Sites with snow cover in early April (30% of all sites) held 96.4% of all individuals recorded. Field observations indicated that Common Redpolls foraged extensively for spruce seeds on the snow until the end of May when young were independent. I suggest that the mass occurrence was due to a unique combination of exceptionally large seed crops of two tree species coinciding in the same year. The masting produced large amounts of food both for overwintering (birch seeds) and for breeding (spruce seeds), and during the breeding season snow cover facilitated access to food resources. Dependency of Common Redpolls on snow cover suggests that climate change may negatively impact some seed-eaters in boreal regions. On the other hand, higher temperatures may induce more frequent masting which may be beneficial for seed-eaters. Thus, climate change is likely to lead to complex ecosystem changes in areas where snow cover may disappear.
Characterization of the Functional Dynamics in the Neonatal Brain during REM and NREM Sleep States by means of Microstate Analysis
Authors: Khazaei Mohammad , Raeisi Khadijeh , Croce Pierpaolo , Tamburro Gabriella , Tokariev Anton , Vanhatalo Sampsa , Zappasodi Filippo , Comani Silvia 
Published: July 2021

AbstractNeonates spend most of their life sleeping. During sleep, their brain experiences fast changes in its functional organization. Microstate analysis permits to capture the rapid dynamical changes occurring in the functional organization of the brain by representing the changing spatio-temporal features of the electroencephalogram (EEG) as a sequence of short-lasting scalp topographies—the microstates. In this study, we modeled the ongoing neonatal EEG into sequences of a limited number of microstates and investigated whether the extracted microstate features are altered in REM and NREM sleep (usually known as active and quiet sleep states—AS and QS—in the newborn) and depend on the EEG frequency band. 19-channel EEG recordings from 60 full-term healthy infants were analyzed using a modified version of the k-means clustering algorithm. The results show that ~ 70% of the variance in the datasets can be described using 7 dominant microstate templates. The mean duration and mean occurrence of the dominant microstates were significantly different in the two sleep states. Microstate syntax analysis demonstrated that the microstate sequences characterizing AS and QS had specific non-casual structures that differed in the two sleep states. Microstate analysis of the neonatal EEG in specific frequency bands showed a clear dependence of the explained variance on frequency. Overall, our findings demonstrate that (1) the spatio-temporal dynamics of the neonatal EEG can be described by non-casual sequences of a limited number of microstate templates; (2) the brain dynamics described by these microstate templates depends on frequency; (3) the features of the microstate sequences can well differentiate the physiological conditions characterizing AS and QS.
In Our Own Words: The Complex Sensory Experiences of Autistic Adults
Authors: MacLennan K. , O’Brien S. , Tavassoli T. 
Published: July 2021

AbstractAutistic adults commonly experience sensory reactivity differences. Sensory hyperreactivity is frequently researched, whilst hyporeactivity and seeking, and experiences across domains, e.g., vision, are often neglected. Therefore, we aimed to understand more about the sensory experiences of autistic adults. We conducted a mixed-methods study, co-produced with stakeholders; recruiting 49 autistic adults who completed an online survey. Firstly, quantitative results and content analysis enhanced our understanding of sensory input/contexts associated with sensory hyperreactivity, hyporeactivity, and seeking across modalities. Secondly, thematic analysis developed themes relating to ‘Outcomes’, ‘Control’, ‘Tolerance and management’, and ‘The role of other people’, informing a theoretical model of sensory reactivity differences in autistic adults. These findings have implications for support services and improving quality of life for autistic adults.
Structural and Thermal Properties of Starch Plasticized with Glycerol/Urea Mixture
Authors: Paluch Magdalena , Ostrowska Justyna , Tyński Piotr , Sadurski Waldemar , Konkol Marcin 
Published: July 2021

AbstractThe paper presents the results of research on the influence of used plasticizing system on the structural and thermal properties of thermoplastic starch (TPS). The thermoplastic starch granulate was obtained by extrusion of native starch in the presence of a plasticizing system using a twin-screw extruder. Glycerol and urea were used as plasticizers in various proportions. In order to evaluate the effectiveness of the starch plasticization process, changes in its chemical structure were analyzed by infrared spectroscopy (FTIR), gel permeation chromatography (GPC) and X-ray diffraction (XRD). TPS thermal stability was determined by thermogravimetric analysis (TGA). An improvement in the efficiency of the plasticization process has been found for a urea-containing plasticizing system compared to the composition of starch plasticized only with glycerol. In addition, the XRD analysis confirms the beneficial effect of urea on the inhibition of starch retrogradation process.
Do governments delay the implementation of parliamentary requests? Examining time variation in implementing legislative requests in Switzerland
Authors: Stadelmann-Steffen Isabelle , Oehrli Dominique , Vatter Adrian 
Published: July 2021

AbstractThis paper investigates time variations in the implementation of legislative requests by the Swiss government. Combining the literature on executive–legislative relations with findings from implementation research, we focus on the procedural level and argue that implementation delays can occur because the government does not want to, cannot or should not implement faster. We test these mechanisms using a unique database, which enables us to analyse a systematic collection of all legislative requests that have been approved between the parliament’s 2003 winter session and its 2018 spring session. Our results show that the considerable variation in the time needed for the legislative mandates’ implementation is mostly related to the Swiss government’s inability to transpose faster, i.e. to factors like highly busy administrative offices or complex and controversial issues. In contrast, there is no support for the ideas that the government “shall not” or “does not want to” transpose faster.
Multidisciplinary studies supporting conservation programmes of two rare, endangered Limonium species from Spain
Authors: González-Orenga Sara , Donat-Torres Ma Pilar , Llinares Josep V. , Navarro Albert , Collado Francisco , Ferrer-Gallego P. Pablo , Laguna Emilio , Vicente Oscar , Boscaiu Monica 
Published: July 2021

Abstract
Background and aims
Two local threatened endemics from Valencian salt marshes were analysed from a multidisciplinary perspective combining field studies with experiments performed under greenhouse-controlled conditions. The work aimed to investigate the habitat of the two species but also to explore their limits of tolerance to severe drought and salinity and the mechanisms behind their stress responses.

Methods
The number of individuals in several populations, climatic conditions, soil characteristics and accompanying vegetation in the natural habitats were analysed in the field study. Plants obtained by seed germination were grown in the greenhouse and subjected to one month of water and salt stress treatments. Growth and biochemical parameters were analysed after the treatments were finalised.

Results
No correlation between climatic parameters and the number of individuals censed of the two Limonium species could be established. Although L. dufourii was found in more saline soils in the natural habitats, under controlled greenhouse conditions, this species was more severely affected by salt treatment than L. albuferae, which is more susceptible to water stress. A common biochemical response was the increase of proline under all stress treatments, but mostly in water-stressed plants. Oxidative stress markers, MDA and H2O2, did not indicate significant differences between the treatments. The differences in the two species' responses to the two kinds of stress were correlated with the activation of the antioxidant enzymes, more pronounced in conditions of salt stress in L. albuferae and of water stress in L. dufourii.

Conclusions
Although L. albuferae is found in sites with lower salinity in the natural habitats, the greenhouse experiment indicated that it tolerates higher concentrations of salt than L. dufouri, which is more resistant to drought. The two species efficiently mitigate oxidative stress by activation of antioxidant enzymes. The results obtained may be helpful for the conservation management of the two species: whereas salinity is not problematic, as the two species tolerated under controlled conditions salinities far beyond those in their natural environments, water scarcity may be a problem for L. albuferae, which proved to be more susceptible to water deficit.
What is the myth of the given?
Authors: O’Shea James R. 
Published: July 2021

AbstractThe idea of ‘the given’ and its alleged problematic status as most famously articulated by Sellars (1956, 1981) continues to be at the center of heated controversies about foundationalism in epistemology, about ‘conceptualism’ and nonconceptual content in the philosophy of perception, and about the nature of the experiential given in phenomenology and in the cognitive sciences. I argue that the question of just what the myth of the given is supposed to be in the first place is more complex than has typically been supposed in these debates, and that clarification of this prior question has surprising consequences. Foundationalism was only one of Sellars’s targets, and this not only in the familiar sense that the more fundamental issues at stake concern the very ‘objective purport’ or intentionality of our empirical thinking in general. When pushed further still, Sellars’s critique in fact hinged on his diagnoses of implicit framework-relative or ‘categorial’ metaphysical presuppositions he exposes in givenist views. Furthermore, the key to his critique accordingly turns out to rest on implicit assumptions concerning the in principle revisability or replaceability of any such presuppositions, whether ‘innate’ or acquired, and including Sellars’s own. Another key result is that widespread assumptions that Sellars’s famous critique is simply inapplicable or irrelevant to either ‘thin’ nonconceptualist views of the given (such as C. I. Lewis’s), since they are ‘non-epistemic’; or alternatively, irrelevant to ‘thick’ conceptualist and phenomenological analyses (since they, too, reject ‘sense-data’ or the ‘bare given’)–both turn out to be mistaken.
Opacity thought through: on the intransparency of computer simulations
Authors: Beisbart Claus 
Published: July 2021

AbstractComputer simulations are often claimed to be opaque and thus to lack transparency. But what exactly is the opacity of simulations? This paper aims to answer that question by proposing an explication of opacity. Such an explication is needed, I argue, because the pioneering definition of opacity by P. Humphreys and a recent elaboration by Durán and Formanek are too narrow. While it is true that simulations are opaque in that they include too many computations and thus cannot be checked by hand, this doesn’t exhaust what we might want to call the opacity of simulations. I thus make a fresh start with the natural idea that the opacity of a method is its disposition to resist knowledge and understanding. I draw on recent work on understanding and elaborate the idea by a systematic investigation into what type of knowledge and what type of understanding are required if opacity is to be avoided and why the required sort of understanding, in particular, is difficult to achieve. My proposal is that a method is opaque to the degree that it’s difficult for humans to know and to understand why its outcomes arise. This proposal allows for a comparison between different methods regarding opacity. It further refers to a kind of epistemic access that is important in scientific work with simulations.
“I’ve Got Many Stories You Know”—Problematizing Silence Among Unaccompanied Migrant Girls
Authors: Ekström Elin , Andersson Ann-Christine , Börjesson Ulrika 
Published: July 2021

AbstractThis paper presents a study on inhabited silence among unaccompanied female minors in Sweden. Silence among unaccompanied minors has often been explained by experienced trauma. Conversely, research also explains silence as a natural way of establishing autonomy during adolescence. By analyzing the narratives of 11 unaccompanied female minors, we aim to problematize and broaden the understanding of silence as a lack of communication. By using Bourdieu’s concept of linguistic capital, we analyze how hegemonic narratives on migration and integration influence how the girls in this study use silence in their everyday interactions. Our findings suggest that silence can be understood as both a rejection of these narratives and a strategy to preserve the girls’ integrity. We also demonstrate how these girls negotiate their linguistic capital in relation to embodiment and othering, thereby pushing boundaries of identity and what it means to be seen as Swedish. The paper concludes that silence itself speaks and shows that what is often perceived as a lack of communication can also be understood as a failure to listen.