bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self-awareness for Financial Decision Making Abilities Is Linked to Right Temporal Cortical Thickness in Older Adults&nbsp;
Authors: Sunderaraman Preeti , Lee Seonjoo , Varangis Eleanna , Habeck Christian , Chapman Silvia , Joyce Jillian L , Hartstone Whitney , Brickman Adam , Stern Yaakov , Cosentino Stephanie 
Published: February 2021

Abstract
Everyday financial decision making and the awareness of the integrity of one’s financial decision making abilities (or financial awareness) are both critical to study in older adults as they can help identify those at risk for making suboptimal financial decisions and prevent financial loss. In the current study, we examined the cognitive and cortical thickness correlates of financial decision making and financial awareness in 59 community-dwelling participants co-enrolled in a larger study (mean age=68.35 years (SD=5.5), mean education=15.91 (SD=2.36), 61% = women, 67% = White). Data from standardized measures of financial decision making and cognition was investigated along with FreeSurfer derived thickness regions. Based on metacognitive frameworks, financial awareness was measured along with a well-validated measure of memory awareness. Results revealed that numeracy, executive functioning and vocabulary were associated with financial decision making, whereas in analysis adjusted for financial decision making, memory awareness relative to cognition was most strongly linked to financial awareness. No significant associations between thickness and financial decision making were found. However, both financial and memory awareness were associated with the same right-hemisphere temporal thickness regions underscoring the idea of a common substrate of awareness. Interestingly, our findings converge with the emerging work on financial exploitation in which the right sided temporal regions have been found to play a prominent role. Incorporating the contributing role of self-awareness in various models of financial exploitation will be an important consideration for future studies.
Streamflow prediction of the Yangtze River base on deep learning neural networks: Impact of the El Niño–Southern Oscillation
Authors: Ha Si , Liu Darong , Mu Lin 
Published: February 2021

Abstract
Accurate long-term streamflow and flood forecasting has always been an important research direction in hydrology research. Nowadays, with climate change, floods, and other anomalies occurring more and more frequently and bringing great losses to society. The prediction of streamflow, especially flood prediction, is important for disaster prevention. Current hydrological models based on physical mechanisms can give accurate predictions of streamflow, but the effective prediction period is only about one month in advance, which is too short for decision making. Previous studies have shown a link between the El Niño–Southern Oscillation (ENSO) and the streamflow of the Yangtze River. In this paper, we use ENSO and the monthly streamflow data of the Yangtze River from 1952 to 2016 to predict the monthly streamflow of the Yangtze River in two extreme flood years by using deep neural networks. In this paper, three deep neural network frameworks are used: Stacked LSTM, Conv LSTM Encoder-Decoder LSTM and Conv LSTM Encoder-Decoder GRU. Experiments have shown that the months of flood occurrence and peak flows predicted by these four models become more accurate after the introduction of ENSO. And the best results were obtained on the Convolutional LSTM + Encoder Decoder Gate Recurrent Unit model.
DNCON2_Inter: Predicting interchain contacts for homodimeric and homomultimeric protein complexes using multiple sequence alignments of monomers and deep learning
Authors: Quadir Farhan , Roy Raj , Halfmann Randal , Cheng Jianlin 
Published: February 2021

Abstract
Deep learning methods that achieved great success in predicting intrachain residue-residue contacts have been applied to predict interchain contacts between proteins. However, these methods require multiple sequence alignments (MSAs) of a pair of interacting proteins (dimers) as input, which are often difficult to obtain because there are not many known protein complexes available to generate MSAs of sufficient depth for a pair of proteins. In recognizing that multiple sequence alignments of a monomer that forms homomultimers contain the co-evolutionary signals of both intrachain and interchain residue pairs in contact, we applied DNCON2 (a deep learning-based protein intrachain residue-residue contact predictor) to predict both intrachain and interchain contacts for homomultimers using multiple sequence alignment (MSA) and other co-evolutionary features of a single monomer followed by discrimination of interchain and intrachain contacts according to the tertiary structure of the monomer. We name this tool DNCON2_Inter. Allowing true-positive predictions within two residue shifts, the best average precision was obtained for the Top-L/10 predictions of 22.9% for homodimers, and 17.0% for higher order homomultimers. In some instances, especially where interchain contact densities are high, DNCON2_Inter predicted interchain contacts with 100% precision. We also developed Con_Complex, a complex structure reconstruction tool that uses predicted contacts to produce the structure of the complex. Using Con_Complex, we show that the predicted contacts can be used to accurately construct the structure of some complexes. Our experiment demonstrates that monomeric multiple sequence alignments can be used with deep learning to predict interchain contacts of homomeric proteins.
Tunable Full-color Room Temperature Phosphorescence of Two Single-Component Zinc(II) Complexes
Authors: Mu Ying , Liu Zhongxin , Fang Xiaoyu , Han Song-De , Pan Jie , Wei Qi , Li Jin-Hua , Wang Guo-Ming 
Published: February 2021

Abstract
Tunable full-color room temperature phosphorescence (RTP) is charming due to its potentials in multiple anti-counterfeitings, all-color displays, and multichannel biomarkers. However, it is a huge challenge to acquire excitation-dependent continuously adjustable full-color RTP from a single-component compound. Herein, we report two Zn(II)−based organic complexes, which are the first examples that present blue, cyan, green, yellow, orange, and red continuously tunable phosphorescence with decent quantum efficiency in response to variation of excitation energy at ambient conditions. The unique photoluminescence property is induced by multiple triplet decay pathways, i.e. 3ligand-centered* and 3charge transfer*. The population and stabilization of the triplet excitons benefit from heavy atom effect of Br ions and restriction of molecular motion due to crystallization. This work contributes an insight for the construction of full-color RTP materials and endows Zn(II)−based organic complexes with fresh features for extensive applications.
Perceived social support and depressive symptoms in Chinese patients with ovarian cancer and the mediating role of resilience
Authors: Pang Xiaoyan , Dong Haiyan , Deng Lei , Zhang Yi 
Published: February 2021

Abstract
BackgroundPatients with ovarian cancer (OC) often suffer from depressive symptoms, but there is little research on coping style such as perceived social support and resilience. The aim of the present study was to explore whether resilience plays a mediating role between perceived social support and depressive symptoms. MethodsA cross-sectional study was performed between August 2018 and March 2019. Perceived social support, resilience, and depressive symptoms were measured with the Multi‐dimensional Scale of Perceived Social Support (MSPSS), the Center for Epidemiologic Studies-Depression (CES-D) scale and the Connor‐Davidson Resilience Scale (CD‐RISC). Hierarchical linear regression analyses were used to assess the mediating role of resilience between these variables. ResultsOf 230 consecutive patients identified, a total of 217 completed questionnaires. After controlling for covariates, perceived social support was negatively correlated with depressive symptoms (β = -0.482, p < 0.01) and explained 22.8% of the variance. In addition, after controlling for covariates and perceived social support, resilience was also negatively associated with depressive symptoms (β = -0.492, p < 0.01) and explained 18.1% of the variance. Bootstrapping test confirmed that the BCa 95% CI for resilience excludes 0 in Table 4 (BCa95% CI: -0.342, -0.143), therefore resilience partially mediated the associations of perceived social support with depressive symptoms. ConclusionsResults revealed that resilience could mediate the association between social support and depressive symptoms, and concluded that it was critical to focus on social support as well as resilience in the management strategy of OC.
Preventing and arresting primary tooth enamel lesions using self-assembling peptide P11-4 in vitro
Authors: Wahba Nour , Schwendicke Falk , Kamel Mohamed Amr , Allam Gehan , Paris Sebastian , Kabil Noha , Jost-Brinkmann Paul-Georg , Elhennawy Karim 
Published: February 2021

Abstract
Background: Self-assembling peptides (SAP) may prevent and/or arrest caries lesions. The aim of the study was to evaluate SAP for caries prevention and arrest in primary tooth enamel in vitro. Methods: 215 extracted primary teeth were used. In the prevention experiment, self-assembling peptide for prevention (SAPP), fluoride varnish/mouthwash (FV/FMW), casein-phosphopeptide amorphous-calcium phosphate (CPP-ACP), nanohydroxy-apatite (nHA) were applied. Samples were subjected to a demineralizing pH-cycling for 14-days. In the arrest experiment, 60 samples were pre-demineralized and induced lesions treated using self-assembling peptide for repair (SAPR), FV, CPP-ACP plus fluoride and resin infiltration (RI), and submitted to pH-cycling. Thirty-five samples were used as negative controls (NC). Mineral loss and its differences (Δ/ΔΔZ) were determined using transversal microradiography. Results: FV (ΔZ median: -46 [interquartile range: 189] vol%×µm) and FMW (-28 [129] vol%×µm) prevented caries significantly more effective than all other groups (p<0.05), which did not show significant preventive effects compared with NC (ΔZ=1446 [378] vol%×µm). RI (ΔΔZ=1808 [2193] vol%×µm) and FV (ΔΔZ=1494 [4274] vol%×µm) arrested lesions compared with NC (ΔΔZ=5605 [1371] vol%×µm; p<0.05), while SAPR and CPP-ACPF did not show such arrest. Conclusions: FV and FMW showed the largest caries-preventive effect, while RI and FV arrested lesion progression in primary tooth enamel in vitro. Clinical significance: Preventing and arresting caries lesion allows decreasing invasive treatment needs and patient’s morbidity and fosters the application of minimal invasive dentistry approach.
Soil Moisture Responses Under Different Vegetation Types to Winter Rainfall Events in a Humid Karst Region
Authors: Yan Weihong , Zhou Qiuwen , Peng Dawei , Wei Xiaocha , Tang Xin , Yuan Ershuang , Wang Yalin , Shi Chunmao 
Published: February 2021

Abstract
Humid karst ecosystems are fragile, with precipitation being the main source of soil moisture recharge. The process of soil moisture recharge and usage varies by vegetation type. To analyze the dynamics of soil moisture under different vegetation types during rainfall events, we continuously monitored soil moisture in arable land, grassland, shrub, and forest areas at 10-minute intervals from November 6, 2019, to January 6, 2020.The arable land was used as a control group. Soil moisture under the different vegetation types responded to light, moderate, and rainstorm events with large rainfall amounts. However, only the soil moisture in the grassland areas responded to a light rainfall event with a rainfall amount of 0.87 mm. The largest soil moisture recharge (12.63 mm) and decline (2.08%) were observed for the grassland areas, with the smallest observed for the forest areas. While the grassland areas showed the greatest decline in soil moisture following rainfall, they were more easily recharged during the winter rainfall events. Soil moisture in forests and shrubs was less recharged than in grasslands but also declined less. Therefore, forests and shrubs are better at retaining soil moisture in winter, which is informative for the formulation of a regional vegetation recovery model.
Dysregulation of circRNA&nbsp;Expression in the Peripheral Blood of Individuals With Schizophrenia and Bipolar Disorder
Authors: Mahmoudi Ebrahim , Green Melissa J. , Cairns Murray 
Published: February 2021

Abstract
Circular RNA (circRNA) are head-to-tail back-spliced RNA transcripts that have been linked to several biological processes and their perturbation is evident in human diseases, including neurological disorders. There is also emerging research suggesting circRNA expression may also be altered in psychiatric and behavioural syndromes. Here, we provide a comprehensive analysis of circRNA expression in peripheral blood mononuclear cells (PBMCs) from 39 patients with schizophrenia and bipolar disorder as well as 20 healthy individuals using deep RNA-seq. We observed systematic alternative splicing leading to a complex and diverse profile of RNA transcripts including 8,762 high confidence circRNAs. More specific scrutiny of the circular transcriptome in schizophrenia and bipolar disorder, compared to a non-psychiatric control group, revealed significant dysregulation of 55 circRNAs with a bias towards downregulation. These molecules were predicted to interact with a large number of miRNAs that target genes enriched in psychiatric disorders. Further replication and cross validation to determine the specificity of these circRNAs across broader diagnostic groups and subgroups in psychiatry will enable their potential utility as biomarkers to be established.
Assessing phytotoxicity and accumulation of trace elements to Lactuca sativa of a contaminated shooting range soil
Authors: Česynaitė Jūratė , Praspaliauskas Marius , Sujetoviene Gintare 
Published: February 2021

Abstract
Shooting range soil contamination with heavy metals is a common problem around the world. Usually, lead is the main contaminant in the shooting ranges. Extreme concentrations of trace elements create a toxic living environment for various plants. The purpose of this study was to evaluate the effect on lettuce (Lactuca sativa L.) grown in contaminated shooting range soil. The results showed that physiological parameters root elongation, shoot length and fresh biomass per plant was negatively affected, especially in the most contaminated site of the shooting range. At the most contaminated shooting range site shoots accumulated higher concentrations of Ni and Zn, roots – Cu, Ni, and Zn. The roots of plants grown in the most contaminated soil accumulated significantly higher concentrations of Cu, Ni and Sb in comparison with control (p < 0.05). Accumulation of Cu, Fe, Mn, Ni, Sb and Zn in the roots of the plants grown in the most contaminated site was higher compared to shoots (p < 0.05). Bioaccumulation factor of lettuce was lower than 1, only BF of Cu and Ni in plants from most contaminated site was significantly higher compared to control. In terms of translocation factor, the TFsoil to root of Cu and Pb among all plants and Ni in plants grown in the most contaminated site above 1 shows that metals absorbed by L.sativa were accumulated in root and lower metal translocation in shoots was determined, except for Mn.
Is Obstructive Sleep Apnoea Associated with Hypoxemia and Prolonged ICU Stay after Type A Aortic Dissection Repair?
Authors: Xi Xin , Chen Yu , Ma Wei-Guo , Xie Jiang , Liu Yong-Min , Zhu Jun-Ming , Gong Ming , Zhu Guang-Fa , Sun Li-Zhong 
Published: February 2021

Abstract
Background : Although obstructive sleep apnoea (OSA) is prevalent among patients with aortic dissection, its prognostic impact is not yet determined in patients undergoing major vascular surgery. We aimed to investigate the association of OSA with hypoxemia and with prolonged intensive care unit (ICU) stay after type A aortic dissection (TAAD) repair. Methods: This study enrolled 83 patients who underwent TAAD repair. OSA diagnosis was confirmed by a preoperative STOP-BANG questionnaire and a sleep test performed within 90 days postoperatively. OSA was defined as an apnoea hypopnea index (AHI) of ≥15/h, while an AHI of >30/h was defined severe OSA. Hypoxemia was defined as an oxygenation index (OI) of <200 mmHg, 6 h postoperatively and prolonged ICU referred to an ICU stay of >72 h. Multivariable analysis was performed to assess the association of OSA with hypoxemia and prolonged ICU stay. Results: OSA was diagnosed in 41 patients (49.4%), which was consistent with the detection by using a preoperative STOP-BANG score of ≥4 (Kappa=0.424, P<0.01). Hypoxemia occurred postoperatively in 56 patients (67.5%). Postoperatively hypoxemia developed mostly in OSA patients (52.4% vs. 83.0%, P<0.01), and particularly in those with severe OSA ( 52.4% vs. 90.5%, P<0.01). The postoperative OI could fairly predict a prolonged ICU stay (area under the curve, 0.719; 95% CI 0.595-0.843; P=0.002). Severe OSA was a predictor of both postoperative hypoxemia (odds ratio [OR] 6.65; 95% CI 1.56-46.26, P<0.01) and prolonged ICU stay (OR 5.58; 95% CI 1.54-20.24, P<0.01). Conclusions: OSA was common in patients with TAAD. Severe OSA was predictive of hypoxemia and prolonged ICU stay after TAAD repair. The STOP-BANG score may offer diagnostic clues to OSA in patients with TAAD.
Glycemic Control Status and Long-term Clinical Outcomes in Diabetic Chronic total occlusion patients: An Observational Study
Authors: Zhang Xuehui , Nie Maoxiao , Chen Xue , Liang Zhe , Zhao Quanming 
Published: February 2021

Abstract
Background: Whether good glycemic control can result in clinical benefits for diabetic chronic total occlusion (CTO) patients are limited and controversial.Methods: We assigned the enrolled patients into 2 groups based on one-year glycosylated hemoglobin A (HbA1c) levels: HbA1c<7% group (n=448) and HbA1c≥7% group (n=581). We further subdivided the patients into the successful CTO revascularization (CTO-SR) and non-successful CTO revascularization (CTO-NSR) groups. Kaplan-Meier analysis and Cox regression before and after propensity score matching were used to compare major adverse cardiovascular events (MACE) and other endpoints.ResultsThere were no significant differences between the groups in terms of the most endpoints in the overall patients. After propensity score-matched analysis, patients with HbA1c < 7.0 tended to be superior in terms of MACE, which was mainly attributed to repeat revascularization but the other endpoints. What’s more, the benefit of the HbA1c <7 group was more prominent among patients with CTO-NSR in terms of MACE, repeat revascularization and target vessel revascularization (TVR). And, the improvement of the HbAc1＜7 group was more prominent among patients without chronic heart failure (CHF) (P=0.027). Conclusions: HbA1c <7.0 was associated with a reduced incidence of MACE, which was mainly attributed to a reduction in repeat revascularization. Well glycemic control can improve diabetic CTO patients’ clinical prognosis, especially in CTO-NSR patients.Trial registration: The present study was approved by the Clinical Research Ethics Committee of Beijing Anzhen Hospital, Capital Medical University (No:2018008X). Informed consent was exempt by the committee.
Prevalence and Related Risk Factors Associated with Coronary Heart Disease (CHD) Among Middle Aged and Elderly Patients with Vision Impairment (VI)
Authors: Qin Shengmei , Wu Hengjing , Wang Hao , Li Qi , Zhou Jie , Wu Jing 
Published: February 2021

Abstract
Objective: To investigate the prevalence and related risk factors associated with coronary heart disease（CHD） among middle aged and elderly patients with vision impairment (VI). Study design: cross-sectional research. Methods: The study was conducted with 1,355 visually impaired adults over 45 years old, recruited from a Rehabilitation Hospital in China. Visual impairment is diagnosed by a doctor according to guidelines. Data was analyzed using multiple correspondence and logistic regression analysis. This research represents an important step towards the development of empirically based practical suggestions for decision-makers and health professionals that support visually impaired middle-aged and elderly people to participate in physical exercise and weight management when needed. Results: Of the 1335 middle aged and elderly adults with VI, a total of 154 (11.5%) developed CHD. Statistical analysis based on age grouping indicated that hypertension, diabetes, blindness, gentle and moderate activity were shown to have a strong association with development of CHD. In addition, fasting plasma glucose, heart rate (<60), and BMI were important risk factors for CHD in the middle-aged group and the elderly group respectively.Conclusion: Suggestions for related policy changes should focus on the social and environmental aspects. This includes developing a more accessible and inclusive environments and providing meaningful information about physical activity and weight management to middle-aged and elderly people with visually impaired.
Osteoporosis is Associated with Varus Deformity in Postmenopausal Women with Knee Osteoarthritis: A Case-Control Study
Authors: Zhang Cheng , Zhuang Zhikun , Chen Xiaojun , Li Keda , Lin Tianye , Pang Fengxiang , Zhang Ying , He Wei , Wei Qiushi 
Published: February 2021

Abstract
Background: Varus deformity of the knee is a common pathological characteristic in knee osteoarthritis (KOA), and not enough attention has been given to the relationship between knee varus deformity and the state of systemic bone mass. The purpose of this study is to evaluate the potential relationship between bone mineral density (BMD) and varus deformity in postmenopausal women with KOA.Methods: This case-control study included 202 postmenopausal women with KOA with or without varus deformity. The hip-knee-ankle angle of the lower extremity (HKA), medial distal femoral angle (MDFA), medial proximal tibial angle (MPTA), and the angle of the joint line (JLCA) were measured in all patients. The BMD of the lumbar (L1-L4), left femoral neck, and left hip were measured by dual-energy X-ray absorptiometry in all patients. The difference in BMD between the knee varus deformity group and the normal limb alignment group was compared, and the relationship between the different angles of limb alignment and the BMD values at different sites was evaluated.Results: The BMD at different sites of the knee varus deformity group was lower than of the normal limb alignment group, and the incidence of osteoporosis was higher. Pearson correlation analysis showed that BMD of the lumbar spine (L1-L4), left femoral neck and left hip joint were positively correlated with the HKA, but negatively correlated with JLCA. MPTA was positively correlated with the left femoral neck and left hip joint BMD, but not correlated with lumbar bone density. Furthermore, in the normal limb alignment group, the HKA was only negatively correlated with JLCA, but not significantly correlated with MDFA and MPTA. In the varus deformity group, the HKA was not only negatively correlated with JLCA but also positively correlated with MDFA and MPTA. Conclusions: Osteoporosis should be an important predicting factor for exacerbating knee varus deformity. Maintaining a systemic bone mass level may help to prevent the progression of knee varus deformity in the treatment of KOA.