bluuebunny/crossref_metadata_2025_split huggingface dataset:
3D B-Rep meshing for real-time data-based geometric parametric analysis
Authors: Maquart Tristan , Elguedj Thomas , Gravouil Anthony , Rochette Michel 
Published: April 2021

AbstractThis paper presents an effective framework to automatically construct 3D quadrilateral meshes of complicated geometry and arbitrary topology adapted for parametric studies. The input is a triangulation of the solid 3D model’s boundary provided from B-Rep CAD models or scanned geometry. The triangulated mesh is decomposed into a set of cuboids in two steps: pants decomposition and cuboid decomposition. This workflow includes an integration of a geometry-feature-aware pants-to-cuboids decomposition algorithm. This set of cuboids perfectly replicates the input surface topology. Using aligned global parameterization, patches are re-positioned on the surface in a way to achieve low overall distortion, and alignment to principal curvature directions and sharp features. Based on the cuboid decomposition and global parameterization, a 3D quadrilateral mesh is extracted. For different parametric instances with the same topology but different geometries, the MEG-IsoQuad method allows to have the same representation: isotopological meshes holding the same connectivity where each point on a mesh has an analogous one into all other meshes. Faithful 3D numerical charts of parametric geometries are then built using standard data-based techniques. Geometries are then evaluated in real-time. The efficiency and the robustness of the proposed approach are illustrated through a few parametric examples.
End-tidal to arterial PCO2 ratio: a bedside meter of the overall gas exchanger performance
Authors: Bonifazi Matteo , Romitti Federica , Busana Mattia , Palumbo Maria Michela , Steinberg Irene , Gattarello Simone , Palermo Paola , Saager Leif , Meissner Konrad , Quintel Michael , Chiumello Davide , Gattinoni Luciano 
Published: April 2021

AbstractBackgroundThe physiological dead space is a strong indicator of severity and outcome of acute respiratory distress syndrome (ARDS). The “ideal” alveolar PCO2, in equilibrium with pulmonary capillary PCO2, is a central concept in the physiological dead space measurement. As it cannot be measured, it is surrogated by arterial PCO2which, unfortunately, may be far higher than ideal alveolar PCO2, when the right-to-left venous admixture is present. The “ideal” alveolar PCO2equals the end-tidal PCO2(PETCO2) only in absence of alveolar dead space. Therefore, in the perfect gas exchanger (alveolar dead space = 0, venous admixture = 0), the PETCO2/PaCO2is 1, as PETCO2, PACO2and PaCO2are equal. Our aim is to investigate if and at which extent the PETCO2/PaCO2, a comprehensive meter of the “gas exchanger” performance, is related to the anatomo physiological characteristics in ARDS.ResultsWe retrospectively studied 200 patients with ARDS. The source was a database in which we collected since 2003 all the patients enrolled in different CT scan studies. The PETCO2/PaCO2, measured at 5 cmH2O airway pressure, significantly decreased from mild to mild–moderate moderate–severe and severe ARDS. The overall populations was divided into four groups (~ 50 patients each) according to the quartiles of the PETCO2/PaCO2(lowest ratio, the worst = group 1, highest ratio, the best = group 4). The progressive increase PETCO2/PaCO2from quartile 1 to 4 (i.e., the progressive approach to the “perfect” gas exchanger value of 1.0) was associated with a significant decrease of non-aerated tissue, inohomogeneity index and increase of well-aerated tissue. The respiratory system elastance significantly improved from quartile 1 to 4, as well as the PaO2/FiO2and PaCO2. The improvement of PETCO2/PaCO2was also associated with a significant decrease of physiological dead space and venous admixture. When PEEP was increased from 5 to 15 cmH2O, the greatest improvement of non-aerated tissue, PaO2and venous admixture were observed in quartile 1 of PETCO2/PaCO2and the worst deterioration of dead space in quartile 4.ConclusionThe ratio PETCO2/PaCO2is highly correlated with CT scan, physiological and clinical variables. It appears as an excellent measure of the overall “gas exchanger” status.
Cross-cultural adaptation of body image assessment instruments for university students: a systematic review
Authors: da Silva Ravine Carvalho Pessanha Coelho , Amaral Ana Carolina Soares , Quintanilha Augusta Karla Silva , de Almeida Vitor Alexandre Rabelo , Rodrigues Marcus Vinicius Freitas , Oliveira Aldair J , Morgado Fabiane Frota da Rocha 
Published: April 2021

AbstractThe theoretical-methodological process of cross-cultural adaptation of scales is fundamental for the expansion of research possibilities related to a given area and population, as instrument adequacy allows for the consistent assessment of the construct being studied. This article aims to highlight the different theoretical-methodological processes of cross-cultural adaptations of scales for assessing body image among young university students. The articles were selected in February 2020, with the following search descriptors: (“body image”) and (young or “college students” or graduating or graduat *) and (“cross-cultural validation” or “cross-cultural adaptation”), in three databases—Scopus, PsycINFO, and Web of Science, without any time restrictions. Altogether, 304 studies were surveyed on the different bases mentioned above, and 14 studies published between 2010 and 2019 were evaluated. This study highlighted the methodological procedures used in the process of cross-cultural adaptation, as well as the population, the types of validity and reliability, and also the main limitations, strengths, and results reported in each study included in this review. The information presented in this review will allow new researchers to make more appropriate choices about instruments for assessing body image in young university students, in addition to presenting the methodological evolution on this theme.
Effect of hydrolysable tannin on nutrient intake obesity and other associated metabolic risk factors in polycystic rats
Authors: Manzoor Faiza , Nisa Mahr Un , Hussain Hafiz Amjad , Khan Muhammad Kamran , Ahmad Rabia Shabir , Ahmad Nazir , Imran Muhammad , Umbreen Huma 
Published: April 2021

Abstract
Background
Food intake and eating behavior are two important risk factors that lead to obesity and other associated metabolic and reproductive disorders like polycystic ovarian syndrome (PCOS). Most of the phytonutrients like hydrolysable tannin (HT) have the ability to reduce the nutrient intake that might be a suitable remedy for weight management of females in their reproductive age. Therefore, the present research is aimed to find out the effect of HT on nutrient intake, weekly body weight, blood glucose, serum lipids, minerals, immunoglobulins and satiety hormones in PCOS rats.

Materials and methods
A total of forty five adult healthy female rats of 56 days old, weighed 135 ± 5 g with two consecutive estrous cycles were selected. In order to induce PCOS in rats, the intramuscular injection of 4 mg/rat/kg Estradiol- Valerate was used. After induction, a Complete Randomized Design was used to divide the rats into five equal groups (n = 9) named as Pc0, Pc0.5, Pc1, Pc1.5 and Pc2. The groups of rats were offered different doses of HT i.e. 0, 0.5, 1, 1.5 and 2 % respectively per kg body weight in solution form through oral gavage once in a day for 60 days.

Results
After the intake of different levels of HT, the statistical results had shown a significant decrease (p < 0.05) in the weekly nutrient intake, body weight, water intake, weight gain, fasting blood glucose in PCOS rats. A similar trend of decrease (p < 0.05) was noticed in serum iron, IgM, IgG, leptin, ghrelin, cholesterol, low density lipoprotein and triglycerides while a significant improvement (p < 0.05) was also observed in high density lipoprotein in the PCOS rats. However, a non-significant effect (p > 0.05) was observed on serum protein and calcium levels.

Conclusions
The study concluded that HT had a therapeutical potential to decrease the nutrient intake and its anti-nutritional property could be used as remedy for the management of body weight, hyperglycemia, dyslipidemia and cardiovascular risk factors of PCOS rats.
On the biocontrol by Trichoderma afroharzianum against Fusarium culmorum responsible of fusarium head blight and crown rot of wheat in Algeria
Authors: Bouanaka Hamza , Bellil Ines , Harrat Wahiba , Boussaha Saoussene , Benbelkacem Abdelkader , Khelifi Douadi 
Published: April 2021

Abstract
Background
Durum wheat (Triticum durum Desf.) is one of the most important cereals in the world. Unfortunately, the wheat plant is a target of several species of the genus Fusarium. This genus causes two serious diseases: fusarium crown rot (FCR) and fusarium head blight (FHB). The search for new indigenous strains of Trichoderma with a high potential for biocontrol against these two diseases was the purpose of this study.

Results
Biocontrol potential of 15 isolates of Trichoderma (T1 to T15), isolated from different rhizosphere soils and Algerian ecosystems, was evaluated against 4 strains of Fusarium culmorum (FC11, FC2, FC4, and FC20); the main causative agent of FCR and FHB. The efficacy of biological control by Trichoderma spp., evaluated by in vitro tests (direct and indirect confrontation), was confirmed by in vivo bioassays. The in vitro results showed a significant inhibition of mycelial growth of F. culmorum species than the control. The highest percentages of inhibition were obtained by T9, T12, and T14 isolates causing a maximum inhibition percentage of 81.81, 77.27, and 80.68%, respectively. T14 was selected for biocontrol in in vivo testing. A tube and pot experiments for FCR against F. culmorum showed that T14 decreased the disease severity with 50 and 63.63% reduction, respectively. FHB infection was significantly reduced by T14 in all durum wheat cultivars tested, where %AUDPC (area under the disease progress curve) reduction was 49.77, 43.43, 48.25, and 74.60% for Simeto, Waha, Bousselem, and Setifis genotypes, respectively. Yields also increased significantly for almost all cultivars. The antagonistic T14 was characterized based on molecular tools, using translation elongation factor1-alpha (TEF1-α) and internal transcribed spacers rDNA (ITS1). The results identified T14 as T. afroharzianum with accession numbers attributed by NCBI GenBank as MW171248 and MW159753.

Conclusions
Trichoderma afroharzianum, evaluated for the first time in Algeria as biocontrol agent, is a promising biocontrol approach against FCR and FHB.
On the potential of Bacillus aryabhattai KMT-4 against Meloidogyne javanica
Authors: Antil Sonam , Kumar Rakesh , Pathak D. V. , Kumar Anil , Panwar Anil , Kumari Anju , Kumar Vinod 
Published: April 2021

Abstract
Background
Nematodes (Meloidogyne spp.) are a major reason behind the global crop yield reduction. The bacterial strain KMT-4 was isolated from nematode-affected tomato (Solanum lycopersicum) rhizosphere at research farms, Hisar, India, and screened for its biocontrol potential against root-knot nematode Meloidogyne javanica as well as checked for its effect on plant growth and yield.

Results
The bacterium KMT-4 was identified as Bacillus aryabhattai based on phenotypic characters and 16S rRNA sequence analysis. During in vitro studies, hatching and mortality of M. javanica were significantly affected due to the antagonistic behavior exhibited by the bacterium. In addition to this, KMT-4 also displayed various direct as well as indirect plant growth-promoting attributes like siderophore production, growth hormone (IAA) production, ammonia excretion, hydrogen cyanide production, and chitinase activity. A pot house experiment conducted on brinjal resulted in nearly 73% reduction in eggs, while 80% reduction in galls in the plant root compared to the untreated and chemically treated plants. The final nematode population also reduced significantly in KMT-4 treatment. It was 1141.6 J2/200cc soil in control and reduced to 108 J2/200 cc soil inoculated with KMT-4. Similar results were obtained in field experiments on brinjal and cucumber conducted in years 2018 and 2019, respectively. Also, a notable enhancement in the plant growth was observed in both pot house experiment and field trials.

Conclusion
The possession of nematicidal activity along with plant growth-promoting properties in B. aryabhattai KMT-4 warrants its employment as a potent biological control agent against M. javanica and a promising substitute of chemical nematicides.
The Control of Wing Kinematics And Flight Forces In Fruit Flies (Drosophila Spp.)
Authors: Lehmann Fritz-Olaf , Dickinson Michael H. 
Published: April 2021

ABSTRACT
By simultaneously measuring flight forces and stroke kinematics in several species of fruit flies in the genus Drosophila, we have investigated the relationship between wing motion and aerodynamic force production. We induced tethered flies to vary their production of total flight force by presenting them with a vertically oscillating visual background within a closed-loop flight arena. In response to the visual motion, flies modulated their flight force by changing the translational velocity of their wings, which they accomplished via changes in both stroke amplitude and stroke frequency. Changes in wing velocity could not, however, account for all the modulation in flight force, indicating that the mean force coefficient of the wings also increases with increasing force production. The mean force coefficients were always greater than those expected under steady-state conditions under a variety of assumptions, verifying that force production in Drosophila spp. must involve non-steady-state mechanisms. The subtle changes in kinematics and force production within individual flight sequences demonstrate that flies possess a flexible control system for flight maneuvers in which they can independently control the stroke amplitude, stroke frequency and force coefficient of their wings.
By studying four different-sized species, we examined the effects of absolute body size on the production and control of aerodynamic forces. With decreasing body size, the mean angular wing velocity that is required to support the body weight increases. This change is due almost entirely to an increase in stroke frequency, whereas mean stroke amplitude was similar in all four species. Despite the elevated stroke frequency and angular wing velocity, the translational velocity of the wings in small flies decreases with the reduction in absolute wing length. To compensate for their small size, D. nikananu must use higher mean force coefficients than their larger relatives.
High-Intensity Interval Training in Patients with Pulmonary Embolism: A Randomized Controlled Trial
Authors: GHRAM AMINE , JENAB YASER , SOORI RAHMAN , CHOOBINEH SIROOS , HOSSEINSABET ALI , NIYAZI SEPIDEH , SHIRANI SHAPOOR , SHAFIEE AKBAR , JALALI ARASH , LAVIE CARL J. , WISLØFF ULRIK 
Published: April 2021

ABSTRACT

Purpose
High-intensity interval training (HIIT) appears to be safe and effective in cardiovascular diseases. However, there is a paucity of data on the effect of HIIT for patients with acute pulmonary embolism (PE). The present randomized controlled trial (RCT) therefore examined the efficiency and safety of HIIT in patients with acute PE.

Methods
In single-center parallel open-label RCT, 24 patients (5 women) discharged recently with a diagnosis of intermediate–high-risk acute PE were randomized (1:1) to supervised HIIT (n = 12) or control (n = 12) group. The primary outcomes were exercise capacity evaluated in terms of the estimated maximal oxygen uptake (eV˙O2max), lung function (forced expiratory volume in 1 s [FEV1]), right ventricular (RV) function (RV/left ventricular diameter [LV] ratio), and health-related quality of life (HRQoL). Safety was the secondary outcome.

Results
Eight weeks of HIIT improved eV˙O2max (+65%, P < 0.001), FEV1 (%) (+17%, P = 0.031), and RV/LV ratio diameter (−27%, P = 0.005), as well as HRQoL. All patients in the HIIT group tolerated exercise training without serious adverse events. The control group did not improve (P > 0.05) eV˙O2max, RV/LV ratio diameter, or HRQoL; however, FEV1 (%) was slightly reduced (−6%, P = 0.030).

Conclusions
The present RCT of a tailored center-based HIIT intervention provides preliminary evidence that this intervention could improve exercise capacity, lung function, RV function, and HRQoL without serious adverse events, which could provide marked clinical benefits after PE. Further larger multicenter randomized controlled studies are needed to confirm these promising findings.
Musculoskeletal Responses to Exercise Plus Nutrition in Men with Prostate Cancer on Androgen Deprivation: A 12-Month RCT
Authors: DALLA VIA JACK , OWEN PATRICK J. , DALY ROBIN M. , MUNDELL NIAMH L. , LIVINGSTON PATRICIA M. , RANTALAINEN TIMO , FOULKES STEPHEN J. , MILLAR JEREMY L. , MURPHY DECLAN G. , FRASER STEVE F. 
Published: April 2021

ABSTRACT

Purpose
Androgen deprivation therapy (ADT) for prostate cancer has multiple adverse effects on musculoskeletal health. This 12-month randomized controlled trial aimed to assess the effects of multicomponent exercise training combined with whey protein, calcium and vitamin D supplementation on bone mineral density (BMD), structure and strength, body composition, muscle strength, and physical function in ADT-treated men.

Methods
Seventy ADT-treated men were randomized to exercise plus supplementation (Ex + Suppl; n = 34) or usual care (control; n = 36). Ex + Suppl involved thrice weekly progressive resistance training plus weight-bearing impact exercise with daily multinutrient supplementation. Primary outcomes were DXA hip and spine areal BMD. Secondary outcomes included the following: tibia and radius pQCT volumetric BMD, bone structure and strength, DXA body composition, pQCT muscle and fat cross-sectional area and muscle density, and muscle strength and physical function.

Results
Sixty men (86%) completed the study. Mean exercise and supplement adherence were 56% and 77%, respectively. There were no effects of the intervention on bone or body composition outcomes. Ex + Suppl improved leg muscle strength (net difference, (95% confidence interval, or CI), 14.5% (−0.2 to 29.2); P = 0.007) and dynamic mobility (four-square-step test time, −9.3% (−17.3 to −1.3), P = 0.014) relative to controls. Per-protocol analysis of adherent participants (≥66% exercise, ≥80% supplement) showed Ex + Suppl preserved femoral neck aBMD (1.9% (0.1 to 3.8), P = 0.026) and improved total body lean mass (1.0 kg (−0.23 to 2.22), P = 0.044) relative to controls.

Conclusions
Exercise training combined with multinutrient supplementation had a limited effect on ameliorating the adverse musculoskeletal consequences of ADT, likely related to the modest intervention adherence.
Adherence to physical distancing guidance in Ireland: a nationally representative analysis from the International COVID-19 Awareness and Responses Evaluation (iCARE) study
Authors: Durand Hannah , Bacon Simon L. , Byrne Molly , Farrell Karen , Kenny Eanna , Lavoie Kim L. , McGuire Brian E. , McSharry Jenny , Meade Oonagh , Mooney Robert , Noone Chris , O'Connor Laura L. , O'Flaherty Kate , Molloy Gerard J. ,   The iCARE Study Team
Published: April 2021

Background:Physical distancing measures (i.e., limiting physical contact with people outside of one’s household, maintaining a 2-metre distance between oneself and others, avoiding non-essential travel, etc.) are among the primary strategies used to prevent transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19). These measures will remain crucial during the rollout of newly developed vaccines to limit community-based spread of COVID-19 and prevent healthcare systems from becoming overburdened. Therefore, it is essential to understand the determinants of public adherence to physical distancing measures to inform current and future public health communications. Methods:As part of the International COVID-19 Awareness and Responses Evaluation (iCARE) study, a cross-sectional survey was conducted to evaluate behavioural responses to physical distancing measures in Ireland. A nationally representative sample of 1000 adults completed the survey over one week in June 2020 during Phase 2 restrictions. Participants completed measures assessing socio-demographic characteristics, theory-based psychological predictors, and physical distancing behaviours.Results:Awareness of restrictions in place at the time of data collection was high overall, as was adherence to most physical distancing measures. Participants aged 25–34 years reported the poorest adherence to maintaining a 2-metre distance from others (71.2%, versus 79–90% for all other age groups), avoiding social gatherings (42.4%, versus 52–62%) and avoiding non-essential travel (63.9%, versus 69–79%). Females were slightly more adherent than were males to most measures. Adherence also varied according to participant beliefs and COVID-19 risk category.Conclusions:These results indicate that adherence to physical distancing guidelines varies depending on the behaviour in question as well as socio-demographic and psychological factors. Although some non-adherence was evident for all physical distancing behaviours, adherence was generally high. Future interventions to improve adherence to physical distancing measures should target individual-level determinants of adherence in tandem with effective public health interventions.
The association between BMI self-selection, self-reported BMI and objectively measured BMI
Authors: Johnson Emily , Millar Seán R. , Shiely Frances 
Published: April 2021

Background: It is challenging to measure BMI accurately in population studies because it is an expensive and time-consuming task. As a result, subjectively measured BMI, calculated from self-reported height and weight, which we know to be inaccurate, is often used. The purpose of this study is to determine whether using a different, subjective method of measuring BMI, BMI self-selection, would be more accurate. BMI self-selection is determined by asking participants to place themselves in one of the BMI categories, underweight, normal weight, overweight or obese. Methods: A quantitative survey conducted in the outpatient departments of two hospitals in the South West of Ireland. Participants >18 years were included. Pregnant women were excluded. The final sample included 70 participants. Survey completion, including self-reported height and weight and BMI self-selection, preceded the objectively measured weight and height. Demographic and lifestyle factors were also recorded. Results: 59% of the sample were overweight or obese –63% of females and 54% of males. The sensitivity for correct BMI self-selection for normal weight, overweight and obese categories was 90%, 36% and 33% respectively. The sensitivity for BMI categories calculated from self-reported height and weight was 83%, 57% and 59% respectively. In analysis, age, regular alcohol consumption, unhealthy diet and lower levels of physical activity were all associated with underestimation of BMI. Conclusion: BMI self-selection is an accurate tool when used with normal weight individuals but shows poorer ability to demonstrate accurate measurement in overweight and obese BMI categories. It is inferior to the traditional self-reported BMI method for measuring BMI levels in the general population. Presently, we recommend continuing with self-reported BMI for BMI measurement in large population studies. However, further testing of BMI classification in larger studies is suggested and investigation into alternative objective methods of measurement is warranted.