bluuebunny/crossref_metadata_2025_split huggingface dataset:
Near‐Infrared Afterglow and Related Photochromism from Solution‐Grown Perovskite Crystal
Authors: Liu Nianqiao , Zheng Wei , Sun Ruijia , Li Xiuling , Xie Xiaoyin , Wang Liangling , Zhang Yuhai 
Published: November 2021

AbstractNear‐infrared (NIR) afterglow is keenly sought in emerging areas including deep‐tissue imaging and night‐vision surveillance, while only few successes in powder phosphors are achieved through solid‐state calcination. In this work, a perovskite single crystal, namely Cs2Na0.2Ag0.8InCl6:Yb3+, is grown in solution via a simple hydrothermal reaction. Through a co‐doping strategy involving both Na+ and Yb3+, dual‐band emission in the visible and NIR region is activated by self‐trapped excitons (STE) and lanthanide ions, respectively. Importantly, the total photoluminescence quantum yield (PL QY) of both bands is boosted to ≈82%. Intriguingly, a long‐lasting afterglow at the NIR band (≈7200 s) and a simultaneous photochromism is observed after ceasing the excitation. Importantly, the transparency of crystals exhibit a pronounced contrast in the decoloration process, enabling a quantitative analysis of photochromism at varied temperatures. On the other hand, the transparent crystals enable the design of a light‐storage battery free of reabsorption, featuring a linear power output with crystal loading. This work proposes a new paradigm to quantitatively correlate the afterglow traps to photochromism, opening many possibilities to practical applications of NIR‐afterglow transparent crystals.
Nonvolatile Logic and Ternary Content‐Addressable Memory Based on Complementary Black Phosphorus and Rhenium Disulfide Transistors
Authors: Xiong Xiong , Kang Jiyang , Liu Shiyuan , Tong Anyu , Fu Tianyue , Li Xuefei , Huang Ru , Wu Yanqing 
Published: November 2021

AbstractHardware realization of in‐memory computing for efficient data‐intensive computation is regarded as a promising paradigm beyond the Moore era. However, to realize such functions, the device structure using traditional Si complementary metal–oxide–semiconductor (CMOS) technology is complex with a large footprint. 2D material‐based heterostructures have a unique advantage to build versatile logic functions based on novel heterostructures with simplified device footprint and low power. Here, by adopting the charge‐trapping mechanism between a black phosphorus (BP) channel and a phosphorus oxide (POx) layer, a nonvolatile CMOS logic circuit based on 2D BP and rhenium disulfide (ReS2) with a high voltage gain of ≈275 is realized with a persistent hysteresis window. A Schmidt‐like flip‐flop using only two transistors is also demonstrated, with far fewer transistor numbers than the conventional silicon counterpart, which usually requires six transistors. Furthermore, four‐transistor (4T) nonvolatile ternary content‐addressable memory (nvTCAM) cells are demonstrated with far fewer transistors for parallel data search. The nvTCAM cells exhibit high resistance ratios (Rratio) up to ≈103 between match and mismatch states with zero standby power thanks to the nonvolatility of the BP transistors. This back‐end‐of‐line compatible nvTCAM shows advantages over other structures with reduced complexity and thermal budget.
Erythropoietic properties of human induced pluripotent stem cells‐derived red blood cells in immunodeficient mice
Authors: Deng Jiusheng , Lancelot Moira , Jajosky Ryan , Deng Qiaomei , Deeb Kristin , Saakadze Natia , Gao Yongxing , Jaye David , Liu Senquan , Stowell Sean R. , Cheng Linzhao , Roback John D. 
Published: November 2021

AbstractTransfusion of red blood cells (RBCs) is a life‐saving intervention for anemic patients. Human induced pluripotent stem cells (iPSC) have the capability to expand and differentiate into RBCs (iPSC‐RBCs). Here we developed a murine model to investigate the in vivo properties of human iPSC‐RBCs. iPSC lines were produced from human peripheral blood mononuclear cells by transient expression of plasmids containing OCT4, SOX2, MYC, KLF4, and BCL‐XL genes. Human iPSC‐RBCs were generated in culture supplemented with human platelet lysate, and were CD34−CD235a+ CD233+ CD49dlow CD71low; about 13% of iPSC‐RBCs were enucleated before transfusion. Systemic administration of clodronate liposomes (CL) and cobra venom factor (CVF) to NOD scid gamma (NSG) mice markedly promoted the circulatory survival of human iPSC‐RBCs following transfusion. While iPSC‐RBCs progressively decreased with time, 90% of circulating iPSC‐RBCs were enucleated 1 day after transfusion (CD235a+ CD233+ CD49d− CD71−). Surprisingly, human iPSC‐RBCs reappeared in the peripheral circulation at 3 weeks after transfusion at levels more than 8‐fold higher than at 1 h after transfusion. Moreover, a substantial portion of the transfused nucleated iPSC‐RBCs preferentially homed to the bone marrow, and were detectable at 24 days after transfusion. These results suggest that nucleated human iPSC‐derived cells that homed to the bone marrow of NSG mice retained the capability to complete differentiation into enucleated erythrocytes and egress the bone marrow into peripheral blood. The results offer a new model using human peripheral blood‐derived iPSC and CL/CVF‐treated NSG mice to investigate the development and circulation of human erythroid cells in vivo.
Severe immersion pulmonary edema in a novice elderly scuba diver after heavy alcohol intake
Authors: Morimatsu Yoshitaka , Nasu Michitaka , Murata Yukio , Kitahara Yusuke , Arakaki Junya , Fukumoto Taizo , Nishikiori Hideharu , Ishitake Tatsuya 
Published: November 2021

BackgroundThere are no reports of immersion pulmonary edema induced by excessive alcohol intake. We describe the case of a novice scuba diver who developed apnea due to immersion pulmonary edema during scuba diving after heavy alcohol intake.Case PresentationA 71‐year‐old hypertensive man, without regular antihypertensive therapy, performed diving after excessive alcohol intake (total amount, approximately 253 g) until the night before. When swimming at a depth of 12 m, the patient experienced chest discomfort and ascended immediately but became unconscious. Respiratory arrest was confirmed, and he spat pink foamy sputum. On hospital admission, hypoxemia was confirmed, and chest radiography revealed butterfly‐shaped shadows. Therefore, mechanical ventilation was initiated. The next day, his blood oxygenation level improved, and the radiographic shadows disappeared. He was discharged on day 7 of hospitalization without sequelae.ConclusionA scuba diver with untreated hypertension might develop immersion pulmonary edema during diving after heavy alcohol intake.
Tailoring of advanced poly(lactic acid)‐based materials: A review
Authors: Milovanovic Stoja , Pajnik Jelena , Lukic Ivana 
Published: November 2021

AbstractPoly(lactic acid) (PLA) stands out as the most promising biodegradable alternative to conventional petrochemical‐based polymers for manufacturing of high‐performance materials applied in medicine, pharmacy, food, textile, and electronic industry. This review was aimed to present the conventional and up‐to‐date technologies for PLA processing including melt blending and molding, hot melt extrusion, 3D printing, foaming, impregnation, thermally induced phase separation, nano‐ and microparticles preparation, wet and dry spinning processes. In addition, the effect of the processing parameters and polymer characteristics on the properties of the final material was elaborated. Diverse possibilities to tailor properties of PLA‐based materials by variation in polymer characteristics and concentration, solvent selection, drying method, processing pressure and temperature, incorporation of bioactive components, and so on were highlighted. The examples of the relations between processing methods, parameters, and end‐product properties are given for a better understanding of all aspects that need to be perceived for fabrication of PLA‐based materials with required performances.
High thermal conductivity graphene oxide/carbon nanotubes/butyl rubber composites prepared by a dry ice expansion pre‐dispersion flocculation method
Authors: Bian Huiguang , Xue Junxiu , Hao Guoqiang , Hao Yingjie , Xie Miao , Wang Chuansheng , Wang Zhifei , Zhu Lin , Xiao Yao 
Published: November 2021

AbstractButyl rubber (IIR) is widely used in tire inner liners and tubes, vulcanization bladders, and shock absorption materials due to its extremely low air permeability, excellent aging resistance, and good energy absorption. However, its low thermal conductivity affects its performance and the service life of the product, while it also limits its application. Therefore, the preparation of butyl rubber composites with high thermal conductivity is of great significance and practical value. This paper proposes the use of a dry ice expansion pre‐dispersion flocculation method to improve the thermal conductivity of butyl rubber composites by simultaneously doping graphene oxide (GO) and multiwalled carbon nanotube (MWCNTs) in butyl latex. The experimental results of this study show that the dry ice expansion pre‐dispersion method uses the huge volume expansion force of dry ice to break the nanofillers aggregates during sublimation, promote the dispersion of nanofillers, and achieve better modification effects. Moreover, GO and MWCNTs have good synergistic thermal conductivity, which can establish a complete three‐dimensional thermal conductivity network inside the composite. When 5 wt% of GO and 5 wt% of MWCNTs were added, GO/MWCNTs/IIR composites exhibited the highest thermal conductivity, which reached 0.423 W m−1 K−1 at 180°C.
Ossification pattern of the unusual pisiform in two‐toed (Choloepus) and three‐toed sloths (Bradypus)
Authors: Gavazzi Lia M. , Kjosness Kelsey M. , Reno Philip L. 
Published: November 2021

AbstractTwo‐toed (Choloepus sp.) and three‐toed (Bradypus sp.) sloths possess short, rounded pisiforms that are rare among mammals and differ from other members of Xenarthra like the giant anteater (Myrmecophaga tridactyla) which retain elongated, rod‐like pisiforms in common with most mammals. Using photographs, radiographs, and μCT, we assessed ossification patterns in the pisiform and the paralogous tarsal, the calcaneus, for two‐toed sloths, three‐toed sloths, and giant anteaters to determine the process by which pisiform reduction occurs in sloths and compare it to other previously studied examples of pisiform reduction in humans and orangutans. Both extant sloth genera achieve pisiform reduction through the loss of a secondary ossification center and the likely disruption of the associated growth plate based on an unusually porous subchondral surface. This represents a third unique mechanism of pisiform reduction among mammals, along with primary ossification center loss in humans and retention of two ossification centers with likely reduced growth periods in orangutans. Given the remarkable similarities between two‐toed and three‐toed sloth pisiform ossification patterns and the presence of pisiform reduction in fossil sloths, extant sloth pisiform morphology does not appear to represent a recent convergent adaptation to suspensory locomotion, but instead is likely to be an ancestral trait of Folivora that emerged early in the radiation of extant and fossil sloths.
Time‐resolved photometry of the high‐energy radiation of M dwarfs with the Star‐Planet Activity Research Cubesat
Authors: Ramiaramanantsoa Tahina , Bowman Judd D. , Shkolnik Evgenya L. , Loyd Robert Oliver Parke , Ardila David R. , Barman Travis , Basset Christophe , Beasley Matthew , Cheng Samuel , Gamaunt Johnathan , Gorjian Varoujan , Jacobs Daniel , Jensen Logan , Jewell April , Knapp Mary , Llama Joe , Meadows Victoria , Nikzad Shouleh , Peacock Sarah , Scowen Paul , Swain Mark R. 
Published: November 2021

AbstractKnow thy star, know thy planet, … especially in the ultraviolet (UV). Over the past decade, that motto has grown from mere wish to necessity in the M dwarf regime, given that the intense and highly variable UV radiation from these stars is suspected of strongly impacting their planets' habitability and atmospheric loss. This has led to the development of the Star‐Planet Activity Research CubeSat (SPARCS), a NASA‐funded 6U CubeSat observatory fully devoted to the photometric monitoring of the UV flaring of M dwarfs hosting potentially habitable planets. The SPARCS science imaging system uses a 9‐cm telescope that feeds two delta‐doped UV‐optimized CCDs through a dichroic beam splitter, enabling simultaneous monitoring of a target field in the near‐UV and far‐UV. A dedicated onboard payload processor manages science observations and performs near‐real‐time image processing to sustain an autonomous dynamic exposure control algorithm needed to mitigate pixel saturation during flaring events. The mission is currently halfway into its development phase. We present an overview of the mission's science drivers and its expected contribution to our understanding of star‐planet interactions. We also present the expected performance of the autonomous dynamic exposure control algorithm, a first‐of‐its‐kind onboard a space‐based stellar astrophysics observatory.
Chemically Coupled Fe2O3/Graphene Hydrogel as Binder‐Free Anode Material for Stable Ni‐Fe Battery with High Energy and Power Density
Authors: Yin Fuqiang , Yang Pingping , Chen Xiaoying , Yang Qing , Xie Jiale 
Published: November 2021

AbstractAqueous nickel‐iron (Ni−Fe) batteries provide a sustainable solution for large‐scale power sources, but their practical applications are still restrained by the nonstable Fe anodes. A simple, inexpensive and mass‐manufacturable one‐pot strategy is used to in situ grow Fe2O3 nanoparticles on graphene sheets for preparing a chemically coupled Fe2O3/graphene hydrogel (Fe2O3@GH), of which the pore structure can be well rationally tuned by the ratio of graphene to Fe2O3. In contrast to the conventional iron oxide/carbon anodes (FeOx/C), Fe2O3@GH anode in Ni−Fe batteries delivers much higher specific capacity (287.2 mAh g−1 vs. 159.5 mAh g−1 at 2 A g−1), better stability (capacity retention of 95 % vs. 61.2 % after 1000 charge/discharge cycles) and superior power density comparable with supercapacitors. More remarkably, the assembled full rechargeable Ni−Fe battery made from Ni(OH)2 microspheres growing on Ni foam (Ni(OH)2 MSs@NF) (+)//Fe2O3@GH (−) achieves excellent cycling stability (retention of 82 % of specific capacity after 500 cycles) at a large operating potential of 1.6 V, while delivering the largest energy density of 203 Wh kg−1 and also a highest power density of 6.4 kW kg−1 among the reported full Ni−Fe batteries. This work holds great promises to fabricate alternative safer high‐performance vehicle batteries.
A ratiometric fluorescence sensor based on carbon quantum dots realized the quantitative and visual detection of Hg2+
Authors: Liu Yalei , Su Luyao , Wang Sui , Guo Zhiyong , Hu Yufang 
Published: November 2021

AbstractIn this paper, based on the fluorescence of carbon quantum dots (CQDs) quenched by mercury ions (Hg2+) and the nonresponse of Hg2+ to rhodamine B fluorescence, a dual emission ratio fluorescence sensor was constructed to realize the quantitative detection of Hg2+. Under excitation at 365 nm, the fluorescence spectrum showed double emission peaks at 437 nm and 590 nm, corresponding to the fluorescence emissions of CQDs and rhodamine B, respectively. This method quantitatively detected Hg2+ based on the linear relationship between the ratio of the intensities of the two emission peaks F437/F590 and the concentration of Hg2+. The detection range was 10–70 nM, and the limit of detection (S/N = 3) was 3.3 nM. In addition, this method could also realize the qualitative and semiquantitative detection of Hg2+ according to the fluorescence colour change of the probe under ultraviolet light. After various evaluations, the method could be successfully applied to the quantitative and visual detection of Hg2+ in tap water, and demonstrated excellent selectivity, anti‐interference performance, and repeatability of the method.
Cloning and Characterization of a Novel Carotenoid Cleavage Dioxygenase 1 from Helianthus annuus
Authors: Qi Zhipeng , Tong Xinyi , Bu Su , Pei Jianjun , Zhao Linguo 
Published: November 2021

AbstractNatural β‐ionone, a high‐value flavoring agent, has been widely applied in the food, cosmetics, and perfume industry. However, attempts to overproduce β‐ionone in microorganisms have been limited by the efficiency of carotenoid cleavage dioxygenases (CCDs), which catalyzes β‐carotene in the biosynthesis pathway. In order to obtain CCD genes responsible for the specific cleavage of carotenoids generating β‐ionone, a novel carotenoid cleavage dioxygenase 1 from Helianthus annuus was cloned and overexpressed in Escherichia coli BL21(DE3). The recombinant CCD was able to cleave a variety of carotenoids at the 9, 10 (9′, 10′) sites to produce C13 products in vitro, including β‐ionone, pseudoionone, 3‐hydroxy‐4‐oxo‐β‐ionone, 3‐hydroxy‐β‐ionone, and 3‐hydroxy‐α‐ionone, which vary depending on the carotenoid substrates. In comparison with lycopene and zeaxanthin, HaCCD1 also showed the high specificity for β‐carotene to cleave the 9, 10 (9′, 10′) double bond to produce β‐ionone in E. coli accumulating carotenoids. Finally, the expression of HaCCD1 in E. coli was optimized, and biochemical characterizations were further clarified. The optimal activity of HaCCD1 was at pH 8.8 and 50 °C. The Vmax for β‐apo‐8′‐carotenal was 10.14 U/mg, while the Km was 0.32 mM. Collectively, our study provides a valuable enzyme for the synthesis of natural β‐ionone by biotransformation and synthetic biology platform.
Three‐Dimensional Porous Carbon Framework Confined Si@TiO2 Nanoparticles as Anode Material for High‐Capacity Lithium‐Ion Batteries
Authors: Hou Li , Xiong Shuangsheng , Cui Ruiwen , Jiang Yang , Chen Rongna , Liang Wenjing , Gao Zeyuan , Gao Faming 
Published: November 2021

AbstractSilicon‐based lithium‐ion battery anodes, in recent years, have caught widespread interest seeing their great theoretical capacity, low charge‐discharge potentials, and ample natural storage. However, poor electrochemical performance is typically observed, attributed mainly to significant volume expansion, unstable solid‐electrolyte interphase, and low intrinsic electronic/ionic conductivity. Numerous attempts have been reported to revamp its electrochemical performance, including the capacity cycle stability and cycle life. Herein, we reported the synthesis of three‐dimensional (3D) Si@TiO2@C nanohybrids adopting a facile three‐step synthesis strategy. Compared with Si@C and C (derived from polyaniline) electrodes, the well‐designed Si@TiO2@C electrode delivered a momentous enhancement in the electrochemical performance thanks to the presence of robust TiO2 shell and polyaniline‐derived porous carbon skeleton to cope with volume changes of silicon during lithiation and promote the electric conductivity of the overall electrode. The Si@TiO2@C hybrid electrode delivered a high initial discharge capacity of 1748.6 mA h g−1 at 100 mA g−1 and a stable reversible capacity of 1112.5 mA h g−1 at 100 mA g−1 after 500 cycles, with the coulomb efficiency of 98.8 %. Moreover, the electrode showed a high reversible capacity of 508.9 mA h g−1 even at 500 mA g−1 at the 500th cycle with the coulomb efficiency of 99.1 %. This work showed the paramount role of TiO2 shell and 3D porous carbon skeleton, being a promising future for designing the next generation of high capacity, long cycle stable anode materials for lithium‐ion batteries.
Hybrid ZnSe‐SnSe2 Nanoparticles Embedded in Nitrogen‐Doped Carbon Nanocube Heterostructures with Enhanced and Ultra‐stable Lithium‐Storage Performance
Authors: Yu Litao , Kim Kyung Su , Saeed Ghuzanfar , Kang Jun , Kim Kwang Ho 
Published: November 2021

AbstractInvited for this month's cover picture are the groups of Prof. Kwang Ho Kim at the Pusan National University (Korea) and Prof. Jun Kang at the Korea Maritime and Ocean University (Korea). The cover picture shows characteristic microstructure images of novel bimetallic selenide composites embedded in N‐doped carbon nanocubes and their enhanced and ultra‐stable electrochemical performances as lithium‐ion battery anodes. Read the full text of the Article at 10.1002/celc.202100846.
Failure‐Experiment‐Supported Optimization of Poorly Reproducible Synthetic Conditions for Novel Lanthanide Metal–Organic Frameworks with Two‐Dimensional Secondary Building Units
Authors: Kitamura Yu , Terado Emi , Zhang Zechen , Yoshikawa Hirofumi , Inose Tomoko , Uji‐i Hiroshi , Tanimizu Masaharu , Inokuchi Akihiro , Kamakura Yoshinobu , Tanaka Daisuke 
Published: November 2021

AbstractInvited for the cover of this issue are Daisuke Tanaka at Kwansei Gakuin University and co‐workers at Kwansei Gakuin University, Hokkaido University, Kyoto University, Japan and KU Leuven, Belgium. The image is a depiction of exploring the desired crystal by decision tree analysis. Read the full text of the article at 10.1002/chem.202102404.
Serial FNA allows direct sampling of malignant and infiltrating immune cells in patients with B‐cell lymphoma receiving immunotherapy
Authors: Mooney Kelly L. , Czerwinski Debra K. , Shree Tanaya , Frank Matthew J. , Haebe Sarah , Martin Brock A. , Testa Stefano , Levy Ronald , Long Steven R. 
Published: November 2021

BackgroundFine‐needle aspiration (FNA) is used to diagnose malignancies, recurrences, and metastases. The procedure is quick and well tolerated and can be facilitated by ultrasound guidance.MethodsThis article describes the authors' experience in using serial FNA to harvest cellular material during 4 clinical trials of immunotherapy by in situ vaccination in patients with low‐grade lymphoma.ResultsTwo hundred ninety‐six FNA samples were collected from 44 patients over a span of approximately 6 weeks for each patient. Samples were sufficient in quantity and quality to be analyzed by flow cytometry and/or single‐cell messenger RNA sequencing. FNA samples yielded an average of 12 × 106 cells with a mean cellular viability of 86%. Material collected from the tumor lymph nodes differed significantly in the proportions and phenotypes of cellular populations in comparison with matched peripheral blood samples. A comparison of flow cytometry results obtained by FNA directly from the patient and by FNA performed ex vivo and a dissociation of the same lymph node after surgical excision confirmed that FNA sampling of the patient accurately represented the tumor and the microenvironment. An analysis of the FNA samples from immunotherapy‐treated target lymph nodes versus nodes from nontreated tumor sites provided insight into the impact of specific immunotherapy regimens.ConclusionsThis is the largest study describing the use of serial FNA sampling to harvest cellular material during immunotherapy clinical trials. The success of this technique opens the door for FNA sampling to expand significantly future investigations of the dynamic effects of investigational agents, be they immunotherapies or targeted therapies.