bluuebunny/crossref_metadata_2025_split huggingface dataset:
Caracterización clínico patológica y hallazgos microbiológicos de la neutropenia febril en pacientes oncohematológicos en una clínica privada en la ciudad de Montería-Colombia.
Authors: Lobatón José Fernando , González Manuel Enrique , Aruachán Sandra Eugenia , Meza Luis Alfredo , García Mara , Borré Diana Patricia , Paz Maza Alicia , Ramírez Rosangela , Pinto Jean Carlos , Rocha Ernesto 
Published: June 2021

Antecedentes: La neutropenia febril es una complicación frecuente en pacientes oncológicos que reciben quimioterapia. Se estima que el 50 % de los pacientes con neoplasias sólidas y más del 80 % con neoplasias hematológicas desarrollan neutropenia y fiebre en algún momento de su evolución. Objetivo: Identificar las características clínico-patológicas, establecer los focos infecciosos y determinar el perfil microbiológico en los pacientes oncológicos que presentaron neutropenia febril, como complicación posquimioterapia y/o de terapias blanco en el Instituto Médico de Alta Tecnología (IMAT) de la ciudad de Montería – Colombia, entre junio de 2014 y junio de 2016. Materiales y métodos: Estudio de tipo descriptivo en pacientes mayores de 18 años con diagnóstico de neoplasia hematológica o tumor sólido maligno, que presentaron neutropenia febril entre junio de 2014 y junio de 2016, que cumplían con los criterios de inclusión. El análisis de la información se realizó con el software R versión 3.5.1. Resultados: Se documentaron 76 casos de neutropenia febril. La edad promedio fue de 43 años y el 55 % de los pacientes era de sexo masculino. El 84.2 % de los casos se presentó en pacientes con neoplasias hematológicas, siendo las leucemias agudas las de mayor prevalencia. En el 68 % se determinó el foco infeccioso; las infecciones del tracto respiratorio fueron el foco infeccioso clínico predominante (21 %). Los bacilos Gram negativos fueron los gérmenes más frecuentemente aislados. Conclusión: Las infecciones del tracto respiratorio fueron el foco infeccioso predominante en los pacientes con neutropenia febril. Los bacilos Gram negativos fueron los principales microorganismos responsables. La tasa de mortalidad relacionada con neutropenia febril fue del 14 %, resultados similares a lo descrito en la población colombiana y a nivel mundial.
The Effect of Public Service Quality on Community Satisfaction in Districts of Gorom Island, Eastern Seram
Authors: Palijama Fientje 
Published: June 2021

The purpose of this research is to know how far influence quality of public services to community satisfaction at the Gorom Island District Office, East Seram Regency. The method used in this research is descriptive method with a quantitative approach. The population of this research is 50 people. Methods of data analysis using simple linear regression analysis, Pearson correlation and coefficient of determination using SPSS 22.0 for windows. The results showed that 1). The quality of public services has a positive effect on consumer / community satisfaction76.9%, meaning that the higher the quality of the services provided, the higher the customer satisfaction. Vice versa, if the lower the quality of service provided, it will decrease by one point, then the consumer / community satisfaction will decrease by 0.769 or 76.9%. 2).From the tests carried out, it is obtained The coefficient of determination is 63.5% of customer / community satisfaction is influenced by the quality of public services, while the remaining 36.5% of customer / community satisfaction is influenced by other variables not examined in this study.
Keywords : Quality of Public Services, and Consumer / Community Satisfaction
The Influencing Factors of Brand Loyalty and Brand Love
Authors: Misra Isra , Sadikin Ali , Achmad Aditya 
Published: June 2021

Loving a brand can cause a positive feeling for the brand and want to use the brand for a long time. Research on the factors that make consumers feel love for a brand is still a little. This study aims to know at the factors that influence brand loyalty and brand love on iphone users in City in Souteast Asia. This research is a quantitative study using a quantitative descriptive approach. The analytical tool in this study is the Smart PLS (Path Analysis) application. The research variables consist of Romanticism (X1), Self Expression (X2), Hedonic Product (X3), Brand Loves (Y1) and Brand Loyalty (Y2) as mediating variables. Samples using the Yamane method with statistical probability methods amounted to 96 from all iphone users whose population is unknown. The results showed that romanticism, self expression and hedonic products directly have not been able to influence brand love and brand loyalty variables. However, with the presence of variable of mediator such as brand love, indirectly romanticism, self expression and hedonic products can influence brand loyalty variables with brand love as an intervening variable. Overall the results of this study are able to explain that intervening plays an important role become a mediator for other variables.
Keywords : Romanticism, Self Expression, Hedonic Products, Brand Loves, and Brand Loyalty
Analisis Penerapan Konsep Kaizen Dalam Pengendalian Biaya MutuPada UD. Ridwan 3A Kabupaten Pinrang
Authors: Salida Amrizal 
Published: June 2021

Analisis Penerapan Konsep Kaizen Dalam Pengendalian Biaya Mutu Pada UD.Ridwan 3A Kabupaten Pinrang. Dalam suatu bidang Usaha Manufaktur perusahaan harus dapat membangun suatu sistem mutu yang senantiasa meningkatkan produknya baik produksi, instalasi maupun kinerja. Penelitian ini bertujuan untuk mengetahui bagaimana penerapan konsep kaizen dapat berpengaruh dalam mengendalikan biaya mutu pada UD.Ridwan 3A Kabupaten Pinrang pada tahun 2018 sampai dengan tahun 2020. Metode pengumpulan data yang digunakan dalam penelitian ini yaitu observasi dan dokumentasi serta kuisioner. Jenis dan sumber data dalam penelitian ini adalah kualitatif dan data yang diperoleh dianalisis dengan metode deskriptif.Hasil penelititan ini menunjukkan bahwa (1) Secara umum, UD. Ridwan 3A telah menerapkan tiga pilar utama yang menjadi aturan dasar dalam menerapkan kaizen. (2) UD. Ridwan 3A masih berusaha melakukan pengendalian biaya mutu yang terjadi dalam kurun waktu antara tahun 2018 hingga tahun 2020.
Identifikasi Biji-Bijian Berdasarkan Ekstraksi Fitur Warna, Bentuk dan Tekstur Menggunakan Random Forest
Authors: Alwi Luthfi , Hermawan Arya Tandy , Kristian Yosi 
Published: June 2021

Abstrak - Proses identifikasi atau pengenalan biji-bijian merupakan aspek penting dalam dunia industri pengolahan pangan. Sebuah industri pangan berskala besar, proses pencampuran beberapa macam biji-bijian dalam pengolahan sebuah produk pangan sangat memperhatikan ketepatan dalam memilih bahan agar tidak terjadi kesalahan dalam proses produksi karena berpengaruh pada hasil akhir dari sebuah produksi. Agar tidak terjadi kesalahan yang fatal, diperlukan sebuah proses identifikasi dari bahan yang digunakan. Dengan sebuah sensor (intelligent camera) yang digunakan dari hasil sebuah proses identifikasi maka sebuah proses produksi produk pangan dapat berjalan dengan baik dan tidak terjadi kesalahan dalam pencampuran bahan. Proses pengidentifikasian terhadap beberapa varian biji-bijian dapat dilakukan dengan cara mengekstraksi fitur dari citra (image) dengan menganalisa melalui parameter warna, bentuk dan tekstur serta melakukan proses pengklasifikasian untuk mengukur tingkat keakuratan. Penelitian ini melakukan identifikasi terhadap varian biji-bijian (padi, jagung, kacang tanah dan kedelai) dengan melakukan ekstraksi fitur warna menggunakan RGB dan HSV, ekstraksi fitur bentuk menggunakan Morphological Threshold dan ekstraksi fitur tekstur menggunakan Grey Level Co-occurrence Matrix (GLCM) dan Local Binary Pattern (LBP). Untuk proses pengklasifikasian, peneliti menggunakan metode Random Forest Classifier (RF) untuk mendapatkan tingkat akurasi yang tinggi dengan batasan-batasan yang mempengaruhi keakuratan dalam proses pengklasifikasian untuk dikembangkan dalam proses selanjutnya. Peneliti menggunakan tools MATLAB R2015b untuk proses identifikasi mulai dari proses ekstraksi fitur sampai proses klasifikasnya. Berdasarkan hasil pengujian yang dilakukan didapatkan tingkat akurasi sebesar 99.8 %. Dapat disimpulkan bahwa pengambilan dataset berupa gambar atau image biji-bijian yang diteliti dapat dijadikan patokan untuk pengidentifikasian dan dapat dikembangkan dalam proses selanjutnya.
Erosión hídrica superficial en la microcuenca del río Mancotal en Jinotega Nicaragua, 1996 - 2015
Authors: Gutiérrez Aguilar Isolina C. , Blanco Chávez Miguel E. 
Published: June 2021

La microcuenca del río Mancotal es un efluente del embalse Apanás que demanda información cuantitativa sobre la tasa de erosión de los suelos. La erosión de los suelos tiene un impacto negativo en la protección del embalse y se ha intensificado por el cambio del uso de vocación forestal a una agricultura de subsistencia. En este contexto, se estimó la erosión hídrica superficial mediante el uso de la Ecuación Universal Revisada de Pérdida de Suelo (RUSLE). Con este modelo se obtuvieron los factores de erosividad, erodabilidad, la longitud y el gradiente de la pendiente, cobertura del suelo y prácticas de conservación. También se encontró que existe una correlación aceptable (r² =0.652), entre los valores de Erosividad de la lluvia (R) y el Índice Modificado de Fournier (IMF), por tanto, se puede estimar la erosividad utilizando los valores del IMF. Los resultados de la investigación mostraron que el 94.46 % de la microcuenca presentó un potencial de erosión alto, superior a 25 Ton/ha/año.
Hybrid DTC strategy based on predictive control with optimization of the PI controller parameters for TPIM drives
Authors: Ahmadi Taleshian Mehdi , Ghanbari Mahmood , Mehdi Rakhtala Seyed 
Published: June 2021

In this paper, a novel hybrid Direct Torque Control (DTC) strategy based on predictive control with optimization of the Proportional-Integral (PI) controller to improve overall performances of Three-Phase Induction Machine (TPIM) drives is proposed. The presented control technique has contained merits of the DTC method such as fast dynamic response, simple structure, less dependence to machine parameters and merits of vector control method such as high accuracy. Furthermore, a hybrid DTC method with optimal voltage vectors is presented. In the proposed control system, Genetic Algorithm (GA) is employed to obtain optimal values of the PI controller parameters. Finally, simulation results under the presented control strategy showed good performances of this method in comparison with DTC and vector control techniques.
Dynamic Characteristics Analysis of Cylinders Bundle Coupling System Under Axial Flow
Authors: SHU Ya-feng , WU Jian-jun , YANG Yong-wei , LIU Wei-ming , TAO Kei-wei 
Published: June 2021

Nuclear reactor fuel assemblies are mainly composed of cylinders bundle(CB), calculating the dynamics characteristics of CB under axial flow can lay a foundation for predicting fretting wear and vibration fatigue. In the paper, the CB coupling dynamic model of forced vibration under pulsating flow is established. And the stability analysis and natural frequency calculation of the CB system under steady flow are compared with the existing results to verify the model. Finally, the Runge-Kutta method is applied to solve the forced vibration equation of the CB under pulsating flow. The influence of the pulsating parameters m, w0, on the amplitude-frequency characteristics and the motion trajectory of the midspan cross section of the CB under forced vibration are analyzed and discussed. The results show that the pulsating parameters have an important influence on the vibration of the CB system.
Phenomenology of Rhythm: The Role of Rhythm in Written Language
Authors: Feilberg Casper , Maul John 
Published: June 2021

Based on existential-phenomenological perspectives from Merleau-Ponty and Løgstrup, we examine the significance of rhythm for written language skills. Rhythm is both omnipresent and a difficult phenomenon
to explore. Methodologically, the article presents phenomenological descriptions and exemplifications, not least a case study of a secondary school student with written language difficulties. Our intention is to illuminate connections between rhythmic perspectives in movement, speech, working memory and language as prerequisites for the acquisition of written language skills. We conclude that rhythm is an essential aspect of our bodily being, and based on the work of Merleau-Ponty, we are able to bring to light relationships between body, rhythm, and written language skills in ways that would not be possible from a natural scientific point of view. Inspired by Merleau-Ponty's analytical approach and the hermeneutic phenomenology of Ricoeur, we will combine an understanding perspective with both human scientific and natural scientific explanations, into a holistic interpretation. The article thus draws empirically on qualitative descriptions of rhythmic phenomena, and theoretically on perspectives from philosophy of language, developmental psychology and neuropsychology, but they are all interpreted in the light of existential-phenomenological ontology.
The Pitch as Meaning-directing Activity: Implications for Students and Education When Fast Pace and a Striving for Novelty Set the Scene
Authors: Nybye Nicolai 
Published: June 2021

The elevator pitch is part of a global tendency toward homogenization of entrepreneurial content in educational programs (Fletcher, 2018), and this article shows how the pitch is naturalized as a new language because it must be decoded in order to pass an innovation course for health students at a Danish University College. A core communicative component of the pitch is speed. Using pragmatism, the article shows how the pitch guides the meaning making of students and how the compressed time element reduces the space for reflection. Thus, the educational rhythm is set by values from the pitch and innovation. Further, the article problematizes how the pitching situation separates the pitched end product both from reflections on possible consequences of new solutions and from the dynamic forces that actually created the pitch.
Comparative sera proteomics analysis of differentially expressed proteins in oral squamous cell carcinoma
Authors: Wong Yin-Ling , Ramanathan Anand , Yuen Kar Mun , Mustafa Wan Mahadzir Wan , Abraham Mannil Thomas , Tay Keng Kiong , Rahman Zainal Ariff Abdul , Chen Yeng 
Published: June 2021

Background
Oral squamous cell carcinoma (OSCC) has increased in incidence from 1990 to 2017, especially in South and Southeast Asia. It is often diagnosed at an advanced stage with a poor prognosis. Therefore, early detection of OSCC is essential to improve the prognosis of OSCC. This study aims to identify the differentially expressed serum proteins as potential biomarkers for oral squamous cell carcinoma (OSCC).

Methods
Comparative proteomics profiling of serum samples from OSCC patients, oral potentially malignant disorder (OPMD) patients, and healthy individuals were performed using two-dimensional gel electrophoresis (2-DE) coupled with mass spectrometry (MS) (n = 60) and bioinformatics analysis. The enzyme-linked immunosorbent assay (ELISA) (n = 120) and immunohistochemistry (IHC) (n = 70) were used to confirm our findings.

Results
The 2-DE analysis revealed that 20 differentially expressed proteins were detected in OPMD and OSCC (p < 0.05). Bioinformatics analysis indicated that the activation of classical complement, liver X receptor/retinoid X receptor (LXR/RXR) activation, and acute phase response signaling pathway are associated with the development and progression of OSCC. Most of the detected proteins are acute-phase proteins and were related to inflammation and immune responses, including apolipoprotein A-I (APOA1), complement C3 (C3), clusterin (CLU), and haptoglobin (HP). The expression levels of CLU and HP in ELISA are consistent with the findings from the 2-DE analysis, except for the mean serum level of HP in OPMD, whereby it was slightly higher than that in control. IHC results demonstrated that CLU and HP are significantly decreased in OSCC tissues.

Conclusion
Decreased expression of CLU and HP could serve as complementary biomarkers of OSCC. These proteins may assist in predicting the outcomes of OSCC patients. However, a larger cohort is needed for further investigation.
Certain Subclass of Bi-univalent Functions Defined by Sălăgean Differential Operator Related with Horadam Polynomials
Authors: Hussein Dhirgam Allawy 
Published: June 2021

The goal of this paper is to introduce and investigate a new subclass of bi-univalent functions using the Horadam polynomials and Sălăgean differential operator. Furthermore, coefficient estimates are given for and Fekete-Szegő inequalities for this subclass are obtained.
Cost‐effectiveness of precision diagnostic testing for precision medicine approaches against non‐small‐cell lung cancer: A systematic review
Authors: Henderson Raymond , Keeling Peter , French Declan , Smart Dave , Sullivan Richard , Lawler Mark 
Published: June 2021

Precision diagnostic testing (PDT) employs appropriate biomarkers to identify cancer patients that may optimally respond to precision medicine (PM) approaches, such as treatments with targeted agents and immuno‐oncology drugs. To date, there are no published systematic appraisals evaluating the cost‐effectiveness of PDT in non‐small‐cell lung cancer (NSCLC). To address this gap, we conducted Preferred Reporting Items for Systematic Reviews and Meta‐Analyses searches for the years 2009–2019. Consolidated Health Economic Evaluation Reporting Standards were employed to screen, assess and extract data. Employing base costs, life years gained or quality‐adjusted life years, as well as willingness‐to‐pay (WTP) threshold for each country, net monetary benefit was calculated to determine cost‐effectiveness of each intervention. Thirty‐seven studies (50%) were included for analysis; a further 37 (50%) were excluded, having failed population‐, intervention‐, comparator‐, outcomes‐ and study‐design criteria. Within the 37 studies included, we defined 64 scenarios. Eleven scenarios compared PDT‐guided PM with non‐guided therapy [epidermal growth factor receptor (EGFR),n = 5; programmed death‐ligand 1 (PD‐L1),n = 6]. Twenty‐eight scenarios compared PDT‐guided PM with chemotherapy alone (anaplastic lymphoma kinase,n = 3;EGFR,n = 17; PD‐L1,n = 8). Twenty‐five scenarios compared PDT‐guided PM with chemotherapy alone, while varying the PDT approach. Thirty‐four scenarios (53%) were cost‐effective, 28 (44%) were not cost‐effective, and two were marginal, dependent on their country’s WTP threshold. When PDT‐guided therapy was compared with a therapy‐for‐all patients approach, all scenarios (100%) proved cost‐effective. Seven of 37 studies had been structured appropriately to assess PDT‐PM cost‐effectiveness. Within these seven studies, all evaluated scenarios were cost‐effective. However, 81% of studies had been poorly designed. Our systematic analysis implies that more robust health economic evaluation could help identify additional approaches towards PDT cost‐effectiveness, underpinning value‐based care and enhanced outcomes for patients with NSCLC.
C
ox,
G
ertrude
M
ary: Her Life and Work
Authors: Anderson R. L. 
Published: June 2021

Abstract
Gertrude Mary Cox was one of the twentieth century pioneers in Statistics. After receiving her BS and MS degrees in Mathematics and Statistics from Iowa State, she took charge of the computing and data analysis in its Statistical Laboratory. She developed and taught classes in Design of Experiments, using real data.
In 1940, she accepted the headship of the newly established Department of Experimental Statistics at North Carolina State. She started staffing with statisticians who had strong programs in applied fields. In 1944, she became the head of an all‐university Institute of Statistics.
In 1949, Gertrude Cox gave up the Headship at NCS to help develop Statistics at the Research Triangle Park in North Carolina; Dr. Cox became RTI's first Director of Statistics Research in 1959. She had received an honorary doctor's degree from NC State in 1958. Her most treasured honor came in 1975, when she was elected to the National Academy of Science.

Dr. Cox received much outside support; a special one helped establish an outstanding statistical genetics program and the development of a strong computer program. She was a founding member of the International Biometrics Society and became President and Editor of its journal,
Biometrics
. She also became President of the American Statistical Association and consulted with many federal organizations. The building housing Statistics at NCS was named Cox Hall in 1977.

Unfortunately, Gertrude contracted leukemia and died in Duke Hospital in 1978.
G
ardner,
M
artin
J
ohn
Authors: Barker David 
Published: June 2021

Abstract
Although Martin Gardner achieved fame for his work at Sellafield, which showed that paternal exposure to ionizing radiation was linked to leukemia in childhood, this discovery came toward the end of a varied and highly productive career in medical statistics. After receiving a first class degree in mathematics, he joined the Medical Research Council Social Medicine Unit at the London School of Hygiene and Tropical Medicine. It was there that he became interested in the problem of why the rates of common diseases vary so much between different parts of Britain—an interest to which he returned repeatedly throughout his career. He carried out a series of novel analyses on the geographical links between socioeconomic conditions and coronary heart disease. Later, at the MRC Environmental Epidemiology Unit in Southampton, he produced two uniquely detailed atlases of mortality in England and Wales.
H
alley,
E
dmond
Authors: Asmar Lina 
Published: June 2021

Abstract
Edmond Halley was born on November 8, 1656 in Haggerton, UK. He was a major English, astronomer, mathematician, and physicist, who was also interested in demography, insurance mathematics (Actuarial Methods), geology, oceanography, geography, and navigation. Moreover, he was considered an engineer and a social statistician whose life was filled with the thrill of discovery. In 1705, he reasoned that the periodic comet—now known as Halley's comet—that appeared in 1456, 1531, 1607, and 1682, was the same comet that appears every 76 years, and accurately predicted that it would appear again in December 1758. His most notable achievements were his discoveries of the motion of stars, which were then considered fixed, and a scheme for computing the motion of comets and establishing their periodicity in elliptical orbits. Edmond Halley died on January 14, 1742 in Greenwich, UK.
Health Statistics, History of
Authors: Feinleib Manning 
Published: June 2021

Abstract
Early work in demography and vital statistics in the seventeenth century was influenced both by the development of probability in relation to gambling problems and by the analysis of astronomic data. The work of Graunt and Petty is described, as is the later work of Pinel and Louis in clinical statistics. In nineteenth century England, Farr's work on classification and registration of vital events was important, and similar developments took place in the United States, where extensive health surveys were established.