bluuebunny/crossref_metadata_2025_split huggingface dataset:
Produksi Bersih Industri Roti di Kota Pontianak
Authors: Lestari Dinda Deli 
Published: November 2021

Abstract Clean production is an activity to increase efforts to handle the waste of an industry. The purpose of this research is to identify the production process, to know the waste generated and to design a clean production that will reduce the waste generated. This research was conducted in a bakery located in Kota Baru, precisely on Jalan Prof. M. Yamin, Kota Baru, Pontianak. The research begins by identifying the general condition of the industry, then identifying the production process and problems in the industry and continuing with the analysis of appropriate clean production alternatives. The recommended clean production is the utilization of eggshell waste into organic fertilizer and handling plastic waste by giving the waste to the nearest waste bank. Keywords: bread industry, clean production, egg shell, minimation of waste Abstrak Produksi bersih adalah kegiatan untuk meningkatkan upaya penanganan limbah suatu industri. Tujuan penelitian ini adalah untuk mengidentifikasi proses produksi, mengetahui limbah yang dihasilkan dan rancangan produksi bersih yang akan mengurangi limbah yang dihasilkan. Penelitian ini dilaksanakan di toko roti yang berlokasi di Kota Baru, tepatnya di Jalan Prof. M. Yamin, Kota Baru, Pontianak. Penelitian diawali dengan mengidentifikasi kondisi umum industri, selanjutnya dilakukan identifikasi proses produksi dan masalah pada industri serta dilanjutkan dengan analisis alternatif produksi bersih yang tepat. Produksi bersih yang disarankan berupa pemanfaatan limbah kulit telur menjadi pupuk organik serta menangani limbah plastik dengan cara memberikan limbah tersebut ke bank sampah terdekat. Kata Kunci: industri roti, kulit telur, minimasi limbah, produksi bersih
Pengaruh Waterfront Terhadap Kondisi Lingkungan Sosial Kelurahan Benua Melayu Laut
Authors: Pratiwi Nana Novita 
Published: November 2021

Waterfront is a concept to support the availability of open spaces in Pontianak City. Besides functioning ecologically, Waterfront can also function aesthetically and economically so that its existence affects the social environment. One of the most popular Waterfront locations for visitors is the Waterfront in Benua Melayu Laut Ubran Village. The study aims to determine the effect of the Waterfront on the conditions of the social environment in Benua Melayu Laut Urban Village. The analysis used is the frequency distribution and composite index. The results showed that the effect of Waterfront on social environmental conditions was high with an index value of 3.01. This influence can be in the form of a positive or negative influence. Positive influences include increased public awareness of the social environment, increased sense of responsibility in maintaining environmental quality, a high sense of care among fellow citizens and increased cooperation in improving environmental quality and aesthetics. The magnitude of this positive influence can have implications for the comfort and safety of the social environment. Meanwhile, the negative effects that can occur are high conflicts and unfair competition which have an effect on the decline in the social security of the Waterfront Benua Melayu Laut.
MEANS OF EXPRESSING AFFECT IN A WORK OF ART: DIDACTIC ASPECT
Authors: Алексеева Марина Геннадьевна , Фролова Вера Александровна 
Published: November 2021

Выделяются два дополнительных индикатора аффективного состояния персонажей художественного драматического теста: контекстуальный и физиологический. В случае со вторым индикатором речь идет об изменении громкости голоса - понижении тона, повышении тона или о его контрастном чередовании, на что указывается в авторских ремарках. Умение дифференцировать оттенки эмоциональных состояний на основе анализа художественного текста способствует развитию эмоционального интеллекта обучаемых, «вчувствованию» в художественный текст на иностранном языке. Занятия по аналитическому чтению формируют, таким образом, одну из дополнительных компетенций будущих преподавателей - способность воспринимать и интерпретировать эмоции других участников образовательного процесса.
The article highlights two additional indicators of the affective state of the characters of the artistic dramatic test: contextual and physiological. In the case of the second indicator, we are talking about a change in the volume of the voice - a decrease in tone, an increase in tone or its contrast alternation, which is indicated in the author's remarks. The ability to differentiate shades of emotional states based on the analysis of a literary text contributes to the development of emotional intelligence of students, «feeling» in a literary text in a foreign language. Analytical reading classes thus form one of the additional competencies of future teachers - the ability to perceive and interpret the emotions of other participants in the educational process.
Kajian Usahatani Cabai Merah di Desa Mendalo Indah Kecamatan Jambi Luar Kota Kabupaten Muaro Jambi
Authors: Yanita Mirawati , Rahman A. 
Published: November 2021

Red chili is one of the horticultural commodities that are commercially cultivated and become one of the strategic commodities. The commodity is used as a householdfood necessity and a pharmaceutical raw material, although productivity and price often fluctuate. This study aims to (1) Counting the cost and receipt of red chili farming in Mendalo Indah village Jambi district outside the city of Muaro Jambi. (2) Analyzing the large income of red chili farming in Mendalo Indah Village, Jambi District Outside Muaro Jambi Regency. This study used primary data of as many as 50 red chili farmers who were taken deliberately (purposive), considering that only Mendalo Indah Village was conducting sustainable red chili farming activities in the Jambi district outside the city. The method of population retrieval used in this study is by census method. The data analysis method used quantitative analysis. Based on the results of the research obtained that the average total cash cost is Rp 16,905,304/farmer/MT and Rp 23,359,273/ha/MT and the unpaid fee (taken into account) is Rp 8,255,687/farmer/MT and Rp 12,322,293/ ha/MT. The average revenue obtained by farmers is Rp 98,071,560/farmer/MT and Rp.146,294,776/ha/MT. so that the average income amounted to Rp 81,166,256/ farmer/MT and Rp 121,143,605/ha/MT. In the future, farmers are expected to manage agricultural inputs by implementing good agricultural practices to increase productivity further.
DIGITAL ELECTRONIC PRACTICUM WITH LOGISIM APPLICATION USING WHATSAPP VIDEO CALL
Authors: Dewantara Dewi 
Published: November 2021

<p>The purpose of this study was to describe the effectiveness and response of students about the Digital Electronics Practicum with the Logisim Application Using Whatsapp Video Call. This type of research is descriptive research. The research subjects were 50 Physics Education Students of Lambung Mangkurat University taking Digital Electronics courses. Data collection techniques are through practicum assessment sheets and student response questionnaires. The results of the student response questionnaire showed that the format, quality, clarity, and interest of the students were in good categories. The results of student practicum assessments show the effectiveness of the Digital Electronics Practicum with the Logisim Application Using Whatsapp Video Call in the good category. Thus it can be concluded that the Digital Electronics Practicum with Logisim Applications Using Whatsapp Video Call is effective to be implemented and gets a very good response from students.. </p>
Oasis. La casa Loewy en el desierto de Palm Spring
Authors: De Miguel Sergio 
Published: November 2021

En los tiempos de la optimista eclosión del Estilo Internacional en América y del comienzo de una nueva domesticidad en California, la peculiar mirada que hiciera el fotógrafo Julius Shulman de la casa Loewy, construida por Albert Frey en el desierto de Palm Springs en 1947, nos permite reconocer las claves de una excepcional pieza de arquitectura.
La simbiótica aportación que hiciera Loewy junto a Frey permite superar ampliamente los rigurosos estándares de lo moderno y consigue exaltar el hedonismo de la cultura del bienestar de la posguerra americana. Atmósfera e intención se unen en una fantástica creación tanto de un espacio como de un tiempo.
Tariqah al-Qawa'id wa at-Tarjamah wa Fa'aliyyatuha fi as-Sahah at-Ta'limiyyah
Authors: Tafida Adam Alhaji 
Published: November 2021

This research aims to introduce the Arabic language situation in Jigawa state-Nigeria, also to disclosure the effectiveness of the grammar and translation method in the development of students language skills and to find a suitable method for the development of language skills. The researcher used the descriptive method to conduct this study, and the most important outcome of the study includes; The grammar and translation method is not appropriate to the objectives of the teaching Arabic language in Jigawa state. The content of the Arabic language in this state is above the students' mental capacity, and does not take into account the individual differences between the students. This study found that the Arabic language teacher in this state, is not aware of the objectives of teaching of Arabic language. There are problems facing students understanding of Arabic language courses, as a result of lack of use of appropriate teaching processes, such as lack of materials and the appropriate teaching aids, and resorting to translation more than explanation with acting, and drawing on the blackboard, and so on.
Guia de gestion de plagas para citricos en la Florida 2016: Interpretacion de los enunciados de PPE en las etiquetas de pesticidas
Authors: Nesheim O. Norman , Fishel Frederick M. , Sanchez Tatiana 
Published: November 2021

Este documento, PI-16-SPAN (the english version is 2016 Florida Citrus Pest Management Guide: Interpreting PPE Statements on Pesticide Labels (CG031)), es uno de una serie de publicaciones del Departamento de Agronomía, Servicio de Extensión Cooperativa de la Florida, Instituto de Alimentos y Ciencias Agrícolas, Universidad de la Florida (UF/IFAS Extension). Fecha de primera publicación: mayo 2014. Repasado noviembre 2016 y septiembre 2019.
Peningkatan Kompetensi Teknologi Komunikasi untuk Lomba Virtual pada Guru Sekolah Dasar di Surabaya Melalui Pelatihan Editing Video
Authors: Maya Setyoningrum Vinda , Tandyomano Danang , Tsyuroyya Tsyuroyya , Mutiah Mutiah , Miftakhul Huda Anam 
Published: November 2021

Melalui pelatihan video editing diharapkan pendidik akan mampu memberikan materi pembelajaran yang menarik dan kreatif bagi peserta didik agar peserta didik lebih focus dan tertarik menerima materi yang disampaikan oleh gurunya. Kualitas pendidik di Kota Surabaya masih perlu ditingkatkan termasuk dalam keterampilan membuat video auidio visual, sehingga diperlukan adanya pelatihan dan bimbingan secara khusus agar tenaga pendidik dapat memiliki skill dalam membuat dan mengedit media pembelajaran berbasis video supaya guru dapat lebih kreatif untuk membuat presentasi materi pembelajaran. Tahapan dalam proses kegiatan pengabdian ini yaitu tahap persiapan, pelaksanaan, evaluasi, dan pembuatan laporan. Hasil dari kegiatan pengabdian ini yaitu peserta pengabdian mampu menggunakan aplikasi editing video, peserta pengabdian berhasil membuat suatu produk video pembelajaran yang menarik dan inovatif, peserta pengabdian antusias untuk mengasah kemampuan eiditing video dengan mengikuti kegiatan perlombaan video editing.
Pengembangan Sensor Kimia Deteksi Albumin dalam Urin untuk Penyakit Gagal Ginjal Berbasis Cobalt (Co)
Authors: Yoedistira Chresiani Destianita , Hardi Elvin Febriyanti , Monica Eva 
Published: November 2021

Penyakit PGK (Penyakit Gagal Ginjal), protein yang hilang melalui urin dapat menyebabkan penurunan kadar albumin atau hipoalbuminemia. Keluarnya albumin melalui urin disebabkan karena adanya penurunan protein yang keluar kedalam filtrat glomerulus. Pengembangan teknologi sensor untuk mendeteksi gagal ginjal. Pada penelitian ini telah dilakukan pembuatan sensor kimia dengan menggunakan reagen cobalt dan amoniak. Pembuatan sensor kimia menggunakan teknik imobilisasi. Teknik imobilisasi merupakan suatu proses pengikatan molekul reagen cobalt pada bahan pendukung yaitu amoniak sehingga molekul reagen dapat tersebar didalam fase pendukung tersebut secara merata dan homogen. Tahap awal pada pembuatan sensor kimia adalah menentukan kondisi reagen yang optimum. Sensor memiliki hasil optimasi dengan pH optimum pH 7. Memiliki linearitas yang baik pada rentang konsentrasi 150-650 ppm dengan nilai koefisien korelasi r = 0,9677. Waktu pakai strip test lebih dari 3 bulan pada suhu ruang. Hasil penelitian validasi metode ini memenuhi persyaratan standar. Pengembangan sensor kimia berbasis cobalt (Co) dapat digunakan untuk mendeteksi PGK (Penyakit Gagal Ginjal) karena telah memenuhi kriteria validasi metode selektivitas, linearitas, akurasi, presisi, LOD dan LOQ sehingga dapat digunakan dalam deteksi albumin dalam urin.
Systematic Review of COVID-19 Treatment and Management
Authors: Tonycheta Chijioke Gospel 
Published: November 2021

COVID-19 is an emerging infectious disease, first reported in Wuhan, China. The deadly disease currently known as SARS-CoV-2 can affect everyone regardless of race, gender or age. However, people suffering from underlying medical conditions such as hypertension, diabetes, and other chronic diseases are at the biggest risk for developing more intense symptoms and complications. The global challenge in the containment of COVID-19 has led to a massive death rate and resulted in many economic, social, and health burdens around the world, leading to the question of the dynamic of COVID-19 management treatment. Therefore, this paper aimed to systematically review different past and present studies to develop a possible solution on how COVID-19 can be managed and treated. The articles were searched from five online databases: Science Direct, PubMed/Medline, Web of Science, Embase, and Scopus. The systematic review was guided by the guidelines presented in the preferred reporting items for systematic reviews and meta-analyses (PRISMA) from 2019–2021. Thirteen articles were included after reviewing seventy-two articles. Three hypotheses guided the study; clinical management, telehealth technology, and performance intelligence as an effective way of managing and controlling COVID-19. The study concludes there is no proven treatment for the virus yet, but clinical treatment, telehealth technology, and performance intelligence can effectively manage and control the virus. It also recommends policymakers should support the development and the implementation of performance intelligence based on the evidence and standardized data available for effective and pandemic resilience health care systems that will address the control and management of the virus.
Keywords: SARS2, SARS-CoV-2, Novel Coronavirus, 2019nCoV, COVID-19.
Quiescin Sulfhydryl Oxidase 2 Overexpression Predicts Poor Prognosis and Tumor Progression in Patients With Colorectal Cancer: A Study Based on Data Mining and Clinical Verification
Authors: Jiang Tao , Zheng Li , Li Xia , Liu Jia , Song Hu , Xu Yixin , Dong Chenhua , Liu Lianyu , Wang Hongyu , Wang Shuai , Wang Renhao , Song Jun 
Published: November 2021

Background: As a member of the atypical thiol oxidase family, quiescin sulfhydryl oxidase 2 (QSOX2) has been reported to play an important role in several biological processes, but the expression and function of QSOX2 in colorectal cancer (CRC) remains elusive.Methods: The difference of QSOX2 expression, and its relationship with clinicopathological features and prognosis in CRC, was analyzed by bioinformatic analysis and validated by clinical CRC specimen cohort. The functional characterization of QSOX2 was detected via in vitro and vivo experiments in CRC cell lines, while the potential signaling pathways were predicted by Gene Set Enrichment Analysis (GSEA).Results: Our data based on bioinformatical analysis and clinical validation demonstrated that the expression of QSOX2 in CRC tissues was significantly upregulated. Additionally, the chi-square test, logistic regression analysis, and Fisher’s exact test showed that QSOX2 overexpression was significantly correlated with advanced clinicopathological parameters, such as pathological stage and lymph node metastasis. The Kaplan–Meier curves and univariate Cox regression model showed that QSOX2 overexpression predicts poor overall survival (OS) and disease-free survival (DFS) in CRC patients. More importantly, multivariate Cox regression model showed that QSOX2 overexpression could serve as an independent factor for CRC patients. In vitro and vivo data showed that the proliferation and metastasis ability of CRC cells were suppressed on condition of QSOX2 inhibition. In addition, GSEA showed that the QSOX2 high expression phenotype has enriched multiple potential cancer-related signaling pathways.Conclusion: QSOX2 overexpression is strongly associated with malignant progression and poor oncological outcomes in CRC. QSOX2 might act as a novel biomarker for prognosis prediction and a new target for biotherapy in CRC.
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis
Authors: Li Qi , Xu Mengping , Li Zhuqing , Li Tingting , Wang Yilin , Chen Qiao , Wang Yanxin , Feng Jiaxin , Yin Xuemei , Lu Chengzhi 
Published: November 2021

Aims: The inflammatory response and apoptosis are the major pathological features of myocardial ischemia/reperfusion injury (MI/RI). Maslinic acid (MA), a natural pentacyclic triterpene with various bioactivities, plays critical roles in the multiple cellular biological processes, but its protective effects on the pathophysiological processes of MI/RI have not been extensively investigated. Our study aimed to determine whether MA treatment alleviate ischemia/reperfusion (I/R)-induced myocardial inflammation and apoptosis both in vitro and in vivo, and further reveal the underlying mechanisms.Methods and results: An MI/RI rat model was successfully established by ligating the left anterior descending coronary artery and H9c2 cells were exposed to hypoxia/reoxygenation (H/R) to mimic I/R injury. In addition, prior to H/R stimulation or myocardial I/R operation, the H9c2 cells or rats were treated with varying concentrations of MA or vehicle for 24 h and two consecutive days, respectively. In this study, our results showed that MA could obviously increase the cell viability and decrease the cardiac enzymes release after H/R in vitro. MA could significantly improve the H/R-induced cardiomyocyte injury and I/R-induced myocardial injury in a dose-dependent manner. Moreover, MA suppressed the expression of inflammatory cytokines (tumor necrosis factor alpha [TNF-α, interleukin-1β [IL-1β and interleukin-6 [IL-6]) and the expressions of apoptosis-related proteins (cleaved caspase-3 and Bax) as well as increased the levels of anti-apoptotic protein Bcl-2 expression both in vitro and in vivo. Mechanistically, MA significantly inhibited nuclear translocation of nuclear factor-κB (NF-κB) p65 after H/R via regulating high mobility group box 1 (HMGB1)/toll-like receptor 4 (TLR4) axis.Conclusion: Taken together, MA treatment may alleviate MI/RI by suppressing both the inflammation and apoptosis in a dose-dependent manner, and the cardioprotective effect of MA may be partly attributable to the inactivation of HMGB1/TLR4/NF-κB pathway, which offers a new therapeutic strategy for MI/RI.
The Trend of TIM3 Expression on T Cells in Patients With Nontuberculous Mycobacterial Lung Disease: From Immune Cell Dysfunction to Clinical Severity
Authors: Wang Ping-Huai , Wu Ming-Fang , Hsu Chi-Yu , Pan Sheng-Wei , Shu Chin-Chung , Cheng Shih-Lung 
Published: November 2021

BackgroundThe incidence of nontuberculous mycobacterial lung disease (NTM-LD) is increasing worldwide. Immune exhaustion has been reported in NTM-LD, but T-cell immunoglobulin and mucin domain-containing protein 3 (TIM3), a co-inhibitory receptor on T cells, has been scarcely studied.MethodsPatients with NTM-LD and healthy controls were prospectively recruited from July 2014 to August 2019 at three tertiary referral centers in Taiwan. We examined TIM3 expression on the T cells from the participants using flow cytometry. TIM3 expression was analyzed for different disease statuses and after treatment. The apoptosis and cytokine profiles were analyzed according to the TIM3 expression.ResultsAmong enrolled subjects (47 patients and 46 controls), TIM3 on CD4+ cells (6.44% vs. 4.12%, p = 0.028) and CD8+ cells (18.47% vs. 9.13%, p = 0.003) were higher in NTM-LD patients than in the controls. The TIM3 level on CD4+ and CD8+ T cells was positively associated with T-cell apoptosis in the NTM-LD patients. In stimulating peripheral blood mononuclear cells using PMA plus ionomycin, a high TIM3 level on T cells correlated with low interleukin-2 and tumor necrosis factor-alpha (TNF-α) on CD4+ cells and interferon-gamma and TNF-α on CD8+ T cells. For clinical manifestation, low body mass index (BMI), positive sputum acid-fast smear, and high radiographic score correlated with high TIM3 expression on T cells. After NTM treatment, TIM3+ decreased significantly on CD4+ and CD8+ T cells.ConclusionsIn patients with NTM-LD, TIM3+ expression increased over CD4+ and CD8+ T cells and correlated with cell apoptosis and specific cytokine attenuation. Clinically, TIM3+ T cells increased in patients with low BMI, high disease extent, and high bacilli burden but decreased after treatment.
Proton Pump Inhibitor Therapy Does Not Affect Prognosis of Cirrhosis Patients With Acute Decompensation and Acute-on-Chronic Liver Failure: A Single-Center Prospective Study
Authors: Sun Shanshan , Ye Wenyi , Zhao Ruihong , Hu Jianhua , Zhang Xuan , Yang Meifang , Zhao Hong , Sheng Jifang 
Published: November 2021

Background: The aim of this study was to investigate the impact of proton pump inhibitor (PPI) therapy on complications and prognosis in cirrhosis patients with and without acute-on-chronic liver failure (ACLF).Materials and Methods: Cirrhosis patients with acute decompensation (AD) (n = 489) admitted in our center were enrolled in this prospective observational cohort study. According to treatment received, patients were identified as users or nonusers of PPI. Clinical and laboratory data, complications during hospitalization, and overall survival were recorded in all the patients.Results: Of the 489 patients, 299 (61.1%) patients received PPI therapy. The logistic regression analysis showed that age, albumin, history of previous hepatic encephalopathy (HE), and the chronic liver failure-sequential organ failure assessment (CLIF-SOFA) score were independent risk factors for HE in patients with decompensated cirrhosis [odds ratio (OR) = 1.07, 95% CI: 1.03–1.12, p = 0.001; OR = 1.13, 95% CI: 1.04–1.24, p = 0.006; OR = 242.52, 95% CI: 40.17–1464.11, p &lt; 0.001; and OR = 2.89, 95% CI: 2.11–3.96, p &lt; 0.001, respectively]. Previous severe liver injury and previous bacterial infections were independent risk factors for spontaneous bacterial peritonitis (SBP) in patients with decompensated cirrhosis (OR = 3.43, 95% CI: 1.16–10.17, p = 0.026 and OR = 6.47, 95% CI: 2.29–18.29, p &lt; 0.001, respectively). The multivariate Cox proportional hazards regression model showed that the type and dose of the PPI used were not related to 28-day and 90-day mortality in cirrhosis patients with AD or ACLF.Conclusion: PPI use does not appear to increase mortality or the risk of HE and SBP in the hospitalized cirrhosis patients with and without ACLF.