bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diffusion tensor magnetic resonance imaging: is it valuable in the detection of brain microstructural changes in patients having migraine without aura
Authors: E. Taman Saher , H. Kamr Wael , M. Belal Tamer , I. Tawfik Ahmed 
Published: December 2021

IntroductionThe aim of this study is to assess the diagnostic value of diffusion tensor magnetic resonance imaging (MRI) in the detection of brain microstructural changes in patients having migraine without aura.Material and methodsOur prospective study included 33 patients having migraine without aura and 15 volunteers with matched age and sex, who underwent brain MRI with diffusion tensor imaging (DTI). The fractional aniso­tropy (FA) and mean diffusivity (MD) of selected grey and white matter regions on both sides were measured and correlated with the neurological clinical examination.ResultsSignificant differences were detected in MD values in the thalamus, globus pallidus, and hippocampus head on the right side of patients versus controls. Also, significant differences of the FA values were detected in the thala­mus, globus pallidus, and hippocampus head on the right side of patients versus controls. Regarding the FA values of the same regions on the left side, a significant difference in the FA value was detected only in the hippocampus head. There was a statistically significant difference in the FA values on both sides of the white matter of the frontal lobes, posterior limbs of the internal capsules, and cerebellar hemispheres in patients compared to controls. There was a statistically significant difference in MD values in the white matter of both frontal lobes, posterior limb of the right internal capsule, and both cerebellar hemispheres in patients compared to controls.ConclusionsDTI can detect microstructural changes of the grey and white matter in patients having migraine without aura that could not be detected by conventional MRI.
Optimizing diagnostic imaging data using LI-RADS and the Likert scale in patients with hepatocellular carcinoma
Authors: Morad Kholoud , F. Moustafa Amr , M. Refaat Amal , AbdEllatif Ahmed , S. ElAzab Mohammed 
Published: December 2021

IntroductionThe study aimed to compare the diagnostic performance of the Liver Imaging Reporting and Data System (LI-RADS), which incorporates fixed criteria, and the Likert scale (LS), which mainly depends on an overall impression in liver lesion diagnosis.Material and methodsDiagnostic data of 110 hepatic nodules in 103 high-risk patients for hepatocellular carcinoma (HCC) were included. Data including diameter, arterial hyperenhancement, washout, and capsule were reviewed by 2 readers using LI-RADS and LS (range, score 1-5). Inter-reader agreement (IRA), intraclass agreement (ICA), and diagnostic performance were determined by Fleiss, Cohen’s , and logistic regression, respectively.ResultsThere were 53 triphasic enhanced computed tomography (CT) and 50 dynamic magnetic resonance (MR) examinations. Overall, IRA was excellent ( = 0.898). IRA was good for arterial hyperenhancement ( = 0.705), washout ( = 0.763), and capsule ( = 0.771) and excellent for diameter ( = 0.981) and tumour embolus ( = 0.927). Overall, ICA between LI-RADS and LS was fair 0.32; ICA was good for scores of 1 ( = 0.682), fair for scores of 2 ( = 0.36), moderate for scores of 5 ( = 0.52), but no agreement was found for scores of 3 ( = –0.059) and 4 ( = –0.022). LIRADS produced relatively high accuracy (87.3% vs. 80%), relatively low sensitivity (84.3% vs. 98%), and significantly higher specificity (89.83% vs. 64.4%) and positive likelihood ratio (+LR: 8.29 vs. 2.75) compared to LS approach.ConclusionsLI-RADS revealed higher diagnostic accuracy as compared to LS with statistical proof higher specificity and +LR showing its ability to foretell malignancy in high-risk patients. We recommend the practical application of the LI-RADS system in the detection and treatment response monitoring of patients with HCC.
Magnetic resonance imaging assessment of cerebral small vessel disease intensification in patients with severe aortic valve stenosis
Authors: Chrostowski Jakub , Majos Marcin , Walczak Andrzej , Wachowski Mariusz , Majos Agata 
Published: December 2021

IntroductionTo assess the prevalence of the neuroradiological indices of cerebral small vessel disease (CSVD) in patients with severe aortic valve stenosis (AS) in magnetic resonance imaging (MRI).Material and methods34 patients (age 60-90 years, 17 women and 17 men) with severe AS and 50 healthy controls (age 61-85 years, 29 women and 21 men) underwent MRI brain examinations, which were analysed for the neuroradiological indices of CSVD: hyperintensities in periventricular white matter (PVWM) and deep white matter (DWM), enlarged perivascular spaces (ePVS), lacunar strokes, and cerebral microbleeds (CMBs).ResultsPVWM hyperintensities were found in 46% of volunteers and was significantly lower (p = 0.027), corresponding to AS patients (80%), the density of lesions was higher in the AS group than in controls (p = 0.019). DWM hyperintensities were found more often in AS patients (76%) than in controls (66%) (p = 0.303), but the densities were similar in both groups. Lacunar strokes were found in 35% of AS patients and 16% of controls (p = 0.042). The average number of lacunar strokes per person was 0.9 in the AS group and 0.3 in the controls (p = 0.035). The AS group showed higher variance in the number of strokes: SD = 1.96 vs. SD = 1.06 in controls. Both prevalence and density of the ePVS and CMBs did not differ significantly between the groups.ConclusionsNeuroradiological indices of the vascular disease do not provide an unequivocal clue to the pathogenesis of CSVD in patients with severe AS. Most observations imply that CSVD is primarily a consequence of cerebral hypoperfusion caused by AS.
Does diffusion-weighted magnetic resonance imaging help in the detection of renal parenchymal disease and staging/prognostication in chronic kidney disease?
Authors: Arora Vijinder , Khatana Jasmin , Singh Kunwarpal 
Published: December 2021

PurposeDiffusion-weighted imaging (DWI) in renal diseases is an upcoming modality, and its utility as an additional marker is yet to be proven. This study was intended to find the relationship between apparent diffusion coefficient (ADC) values with renal function tests and stages of chronic kidney disease (CKD) to assess renal dysfunction, and to label a cut-off for normal renal function and dysfunction.Material and methodsA prospective diagnostic study was conducted on 120 patients: 60 with deranged renal function tests (RFT) and 60 with normal RFT. DWI using a 1.5-Tesla MRI (at b-values of 0 and 500 s/mm<sup>2</sup>) was done. A region
of interest of size 1-2 cm<sup>2</sup> was placed on renal parenchyma in the region of medulla, one each, over the superior, mid, and lower regions of each kidney separately. ADC values were recorded for renal parenchyma and compared.ResultsIn patients with renal dysfunction ADC values were significantly lower than in patients with normal function (1.75 ± 0.25 vs. 2.28 ± 0.21 of right kidney and 1.79 ± 0.17 vs. 2.29 ± 0.21 of left kidney [×10<sup>−3</sup> mm<sup>2</sup>/s]; p = 0.001). ADC values of different stages of CKD showed a decreasing trend with increasing stage.ConclusionsADC values taken at all poles to get focal involvement of the kidney can be used to measure each kidney separately, and values can be individually correlated with the elevated renal parameters. The cut-off value of the mean ADC for individual kidneys was > 2.28 (×10−3 mm<sup>2</sup>/s) in normal renal function and < 2.00 (×10<sup>−3</sup> mm<sup>2</sup>/s) in renal dysfunction.
ĐÁNH GIÁ THỰC TRẠNG LIỆU PHÁP TẬP THỞ Ở BỆNH NHÂN CHẤN THƯƠNG NGỰC CÓ DẪN LƯU MÀNG PHỔI TẠI TRUNG TÂM TIM MẠCH VÀ LỒNG NGỰC - BỆNH VIỆN HỮU NGHỊ VIỆT ĐỨC
Authors: Hữu Lư Phạm , Văn Thuỷ Đoàn 
Published: December 2021

Đặt vấn đề: Lý liệu pháp hô hấp (bao gồm liệu pháp tập thở) là một can thiệp điều trị bắt buộc sau phẫu thuật lồng ngực cũng như sau chấn thương ngực có dẫn lưu màng phổi, có ý nghĩa rất quan trọng giúp nhanh chóng đẩy đờm dãi, máu ra khỏi đường hô hấp, chống xẹp phổi, giúp phổi nở sát thành ngực, góp phần đẩy hết máu - khí ra khỏi khoang màng phổi. Nghiên cứu này nhằm đánh giá thực trạng sự tuân thủ thực hiện liệu pháp với người bệnh sau chấn thương ngực có dẫnl lưu màng phổi trong thời gian gần đây. Phương pháp: Nghiên cứu mô tả cắt ngang-tiến cứu: kết quả nghiên cứu ghi nhận ở các biến số: tuổi, giới tính, tổn thương kèm theo ,thực trạng tuân thủ thực hiện liệu pháp tập thở… Số liệu được thu thập theo mẫu bệnh án nghiên cứu cho từng bệnh nhân và xử lý bằng chương trình SPSS 20.0. Kết quả: Từ tháng 6/2020 đến 11/2020 có 98 bệnh nhân chấn thương ngực có dẫn lưu màng phổi được lựa chọn vào nhóm nghiên cứu với tỷ lệ thực hiện đúng đủ các bước của liệu pháp tập thổi bóng 76%, tiếp theo liệu pháp thở chúm môi là 46%, liệu pháp tập thở cơ hoành có tỷ lệ 27%. Kết luận: Liệu pháp tập thở là một liệu pháp quan trọng trong chăm sóc bệnh nhân chấn thương ngực có dẫn lưu màng phổi.
ĐÁNH GIÁ KẾT QUẢ NGẮN HẠN NONG BÓNG VÀ ĐẶT GIÁ ĐỠ TRONG ĐIỀU TRỊ TẮC ĐỘNG MẠCH CHẬU TASC II A, B
Authors: Đức Tín Lê , Minh Ánh Phạm , Kim Quế Đỗ 
Published: December 2021

Mục tiêu: Đánh giá kết quả ngắn hạn nong bóng và đặt giá đỡ trong điều trị tắc động mạch chậu TASC II A, B. Phương pháp: hồi cứu mô tả. Kết quả: Nghiên cứu có 137 bệnh nhân, nam chiếm 84,7%, tuổi trung bình 70,4 ± 10,9 mẫu nghiên cứu. Phân độ TASC II A chiếm 48,9% (67 trường hợp), phân độ TASC II B chiếm 51,1% (70 trường hợp). Nhóm nong bóng đơn thuần có tỷ lệ phân loại B thấp hơn nhóm đặt giá đỡ (28,6% so với 63,6%, p < 0,001). Thời gian can thiệp trung bình của nhóm nong bóng và đặt giá đỡ lần lượt chiếm 157 ± 39,7 phút và 147 ± 56,4 phút. Thời gian nằm viện trung bình của nhóm nong bóng và đặt giá đỡ lần lượt chiếm là 4,4 ± 1,7 ngày và 4,8 ± 3,1 ngày. Biến chứng chung chiếm 4,4%, trong đó tắc mạch 0,73%, nhồi máu cơ tim 0,73%, cắt cụt 1,5%, tụ máu đường vào 0,73%, suy thận 0,73% mẫu nghiên cứu. Kết quả thành công về kỹ thuật nong bóng và đặt giá đỡ lần lượt chiếm 95,9% và 96,6% mẫu nghiên cứu. Thành công về mặt lâm sàng ở giai đọan ngắn hạn của nong bóng và đặt giá đỡ lần lượt chiếm 97,9% và 96,7%, khác biệt không có ý nghĩa thống kê (P = 0,67). Kết luận: Nong bóng và đặt giá đỡ trong điều trị tắc động mạch chậu tổn thương TASC II A, B là ít xâm lấn, an toàn, hiệu quả, thời gian nằm viện ngắn, hồi phục nhanh. Cả hai phương pháp đều cải thiện các triệu chứng lâm sàng và cận lâm sàng sau can thiệp, ít biến chứng. Tỷ lệ thành công về lâm sàng ở giai đoạn ngắn hạn của phương pháp nong bóng và đặt giá đỡ tương đương nhau.
GAMBARAN PERESEPAN OBAT ANTIHIPERTENSI DI PUSKESMAS TELUK NIBUNG KOTA MADYA TANJUNG BALAI
Authors: Rambe Robiatun , Marpaung Nurhayati 
Published: December 2021

Hipertensi merupakan suatu keadaan seseorang mengalami peningkatan tekanan darah di atas normal yaitu tekanan darah sistolik. Hipertensi perlu mendapat penanganan, salah satunya penanganan antihipertensi dengan pemberian antihipertensi. Penelitian ini bertujuan untuk mengetahui Gambaran Peresepan Obat Antihipertensi di Puskesmas Teluk Nibung Kota Madya Tanjung Balai.Penelitian ini merupakan penelitian deskriptif. Penelitian ini telah dilaksanakan pada Juni 2020 sampai dengan Desember 2020. Populasi dalam penelitian ini adalah pasien hipertensi yang mendapat obat antihipertensi di Puskesmas Teluk Nibung sebanyak 483 orang pada tahun 2020. Pengambilan sampel menggunakan Simple sampling sampling yang ditentukan berdasarkan rumus Slovin sebanyak 83 orang. Hasil Penelitian didapat bahwa Obat antihipertensi yang tersedia di Puskesmas Teluk Nibung Kota Madya Tanjung Balai adalah Amlodipine 10 mg, Captopril 12,5 mg dan Captopril 25 mg, Penggunaan Obat Antihipertensi yang paling sering diresepkan di Puskesmas Teluk Nibung Kota Madya Tanjung adalah Amlodipine 10 mg. Saran dalam penelitian ini diharapkan dengan adanya penelitian ini Puskesmas Teluk Nibung Kota Madya Tanjung Balai terus berkontribusi memberikan pengobatan kepada masyarakat khususnya penyakit hipertensi untuk mencegah terjadinya komplikasi penyakit.
Kata kunci: Gambaran Penggunaan Antihipertensi
Reduced-complexity air quality intervention modeling over China: the development of InMAPv1.6.1-China and a comparison with CMAQv5.2
Authors: Wu Ruili , Tessum Christopher W. , Zhang Yang , Hong Chaopeng , Zheng Yixuan , Qin Xinyin , Liu Shigan , Zhang Qiang 
Published: December 2021

Abstract. This paper presents the first development and evaluation
of a reduced-complexity air quality model for China. In this study, the
reduced-complexity Intervention Model for Air Pollution over China (InMAP-China)
is developed by linking a regional air quality model, a reduced-complexity
air quality model, an emission inventory database for China, and a health
impact assessment model to rapidly estimate the air quality and health
impacts of emission sources in China. The modeling system is applied over
mainland China for 2017 under various emission scenarios. A comprehensive
model evaluation is conducted by comparison against conventional Community Multiscale Air Quality (CMAQ) modeling system
simulations and ground-based observations. We found that InMAP-China
satisfactorily predicted total PM2.5 concentrations in terms of
statistical performance. Compared with the observed PM2.5
concentrations, the mean bias (MB), normalized mean bias (NMB) and
correlations of the total PM2.5 concentrations are
−8.1 µg m−3, −18 % and 0.6, respectively. The statistical performance is
considered to be satisfactory for a reduced-complexity air quality model and
remains consistent with that evaluated in the USA. The
underestimation of total PM2.5 concentrations was mainly caused by its
composition, primary PM2.5. In terms of the ability to quantify source
contributions of PM2.5 concentrations, InMAP-China presents similar
results to those based on the CMAQ model, with variation
mainly caused by the different treatment of secondary inorganic aerosols in
the two models. Focusing on the health impacts, the annual
PM2.5-related premature mortality estimated using InMAP-China in 2017
was 1.92 million, which was 250 000 deaths lower than estimated
based on CMAQ simulations as a result of the underestimation of PM2.5
concentrations. This work presents a version of the reduced-complexity air
quality model over China that provides a powerful tool to rapidly assess the air
quality and health impacts associated with control policy and to quantify
the source contribution attributable to many emission sources.
GRANUL EFFERVESCENT KOMBINASI BUNGA TELANG (Clitoria ternatea) DAN JERUK KALAMANSI (Citrus microcarpa) SEBAGAI ALTERNATIF MINUMAN KESEHATAN
Authors: Putri Nurwigya Mohamad , Slamet Nangsih Sulastri , Wicita Prisca Safriani , Imran Arlan K 
Published: December 2021

Bunga telang (Clitoria ternatea) adalah tanaman yang memiliki potensi farmakologis sebagai antioksidan, antimikroba, antiparasit, anti-inflamasi, antikanker, antihistamin. Jeruk kalamansi (Citrus microcarpa) merupakan tanaman yang sangat kaya akan mineral dan vitamin C sehingga sangat baik digunakan untuk bahan baku minuman kesehatan. Sediaan granul effervescent adalah hasil dari gabungan senyawa asam dan basa yang bila ditambahkan dengan air (H2O) akan bereaksi melepaskan karbon dioksida (CO2), sehingga efek ini akan menghasilkan buih pada sediaan. Tujuan dari penelitian ini adalah untuk memanfaatkan bunga telang dan jeruk kalamansi sebagai bahan aktif dan untuk menghasilkan sediaan granul effervescent sebagai alternatif minuman kesehatan. Ekstrak bunga telang diperoleh dari metode ekstraksi sederhana dengan cara diblender menggunakan air (1:3). Sari jeruk kalamansi diperoleh dari perasan buahjeruk kalamansi. Hasil penelitian menunjukkan bahwa sediaan granul effervescent kombinasi bunga telang dan jeruk kalamansi ini memiliki warna granul putih keunguan dan larutan biru muda bening serta memiliki bau dan rasa kombinasi bunga telang dan jeruk kalamansi, waktu dispersi yang memenuhi persyaratan waktu larut yakni 1 menit 4 detik dan indeks kompresibilitas 13,3%. Berdasarkan penilaian panelis dari parameter tekstur, warna, aroma dan rasa menunjukkan rata-rata 4,3 dengan kategori suka.Kata Kunci : Bunga telang, Jeruk kalamansi, Granul effervescent
SIMULAÇÃO DE EVENTO DISCRETO: ESTUDO DE CASO DE UM LAVA A JATO
Authors: Quintão Elizângela , Coelha Sionara , Neto José Paulo Da Silva , Silva Patrícia Lidiane Carneiro , Rezende Bruna Aparecida 
Published: December 2021

Cada vez mais as empresas procuram formas para tomadas de decisões a respeito do processo produtivo ou serviço a ser prestado, de forma a melhor atender os seus clientes. Diante deste cenário, a simulação tem se tornado uma ferramenta bastante útil. O objetivo do presente estudo foi demonstrar a aplicabilidade da técnica SED em um lava-jato, norteado por um estudo de caso realizado no Centro Automotivo de pequeno porte, localizado em Antônio Pereira, Ouro Preto/Minas Gerais (MG). Foi realizado o levantamento dos recursos materiais e humanos para verificar quais são os gargalos do sistema, comprovando assim, a importância da técnica de SED em empreendimentos de prestação de serviços. A partir das informações disponibilizadas pelos proprietários e cronometragem dos tempos de chegada e atendimento, foi possível realizar a simulação do processo de lavagem e/ou acabamento nos veículos leves, veículos de carga e equipamentos por meio do software Arena. Os resultados do cenário real evidenciaram que a retenção dos recursos utilizados para lavagem é de 91,70% ocasionando congestionamento na fila e aumento do tempo de espera. No cenário simulado, a taxa de utilização reduziu para 83,12%, o que contribuiu para a minimização do tamanho da fila e o tempo de espera.
Perspectivas da proteção ao meio ambiente ante o Estatuto da Cidade
Authors: Silva Suelem Da Costa , Gorczevsk Clovis 
Published: December 2021

RESUMO
O presente artigo emprega o método de revisão de literatura com a finalidade de analisar o Estatuto da Cidade após 20 anos de sua vigência, considerando o objetivo da proteção ambiental no espaço urbano. Parte-se da premissa de que o Estatuto da Cidade representa um marco normativo e principiológico para a proteção ambiental coadunando com o esforço institucional internacional em conciliar economia e sustentabilidade. Fixa-se o objetivo de apontar de que forma o Estado está responsabilizado para com políticas públicas de proteção ambiental, como transcorre a mobilização política e social e a formulação de práticas protetivas com centralidade no direito ambiental. Busca-se especificar como a Política Nacional do Meio Ambiente coaduna com o Estatuto da Cidade permitindo que o Estado brasileiro responda as demandas de sustentabilidade à nível local, regional e nacional. Incluso, verifica-se de que forma o Estatuto responde a Agenda 2030 e aos Objetivos de Desenvolvimento Sustentável, coadunando princípios do direito urbanístico e do direito ambiental. Entende-se que no âmbito das perspectivas de proteção ambiental a partir do Estatuto da Cidade tem-se a sedimentação principiológica da proteção dos recursos ambientais e a consolidação de um processo de urbanização que respeita as funções sociais da cidade, demandando-se, apenas uma maior mobilização social e um esforço político extensivo em prol do ambiente urbano sustentável.
Palavras-chave: Estatuto da Cidade. Sustentabilidade. Cidades sustentáveis. Meio ambiente. Direito urbanístico.
PENGARUH KARAKTERISTIK INDIVIDU DAN LINGKUNGAN KERJA NON FISIK TERHADAP KINERJA KARYAWAN DEPARTEMEN PARTS PT TRAKINDO UTAMA CABANG SAMARINDA
Authors: Juliana Juliana 
Published: December 2021

Individual characteristics and work environment are considered as crucial aspects for companies that want to improve their employees’ performance. PT Trakindo Utama specifically Samarinda branch is one of many branches of PT Trakindo Utama in Indonesia, which become the sole agent of Caterpillar products in Indonesia. Caterpillar itself is the world's leading manufacturer of heavy equipment originally from USA. This research aims to determine the influence of characteristics and non-physical work environment of the employee performance in parts Department at PT Trakindo Utama Samarinda branch. The individual characteristics (x1) and non-physical work environment (x2) are used as independent variables while the performance of employees (Y) as dependent variable. Primary data is obtained by conducting interviews to 34 respondents by using questionnaires while secondary data is obtained by conducting field observation. Data analysis uses a double linear regression technique by using SPSS 22 software. The results show that the individual characteristic variables does not have any partial effect toward the performance of the employees of Parts Department PT Trakindo Utama Cabang Samarinda branch and individual characteristic variables (X1) and non-physical work environment (x2) are simultaneously influential in the performance of the Employees (Y) Parts Department at PT trakindo Utama, Samarinda branch. Suggestions for PT Trakindo Utama Samarinda Branch, the company should hold a family gathering in order to improve not only for each employees relations but also with bosses to stay awake, provide suggestions and evaluate employee work which can effectively improve employee performance, manage the best possible time so that the job can be completed on time.
Probable maximum precipitation for the catchment of Koyna dam
Authors: RAKHECHA P. R. , A. K. KULKARNI A. K. A. K. KULKARNI , MANDAL B. N. , SANGAM R. B. , DESHPANDE N. R. 
Published: December 2021

Estimates of Probable Maximum Precipitation (PMP) for different durations were made for the catchment above Koyna dam on the Koyna river. The catchment spans an area of 892 km2 and the PMP estimates were made for a range of durations of 1 to 3 days. The PMP estimates for Koyna dam were found to be 48, 87 and 117 cm by the physical method and 54, 89 and 124 cm by statistical method for 1, 2 and 3 day respectively. These estimates can be used to check the existing spillway design flood of Koyna dam.