bluuebunny/crossref_metadata_2025_split huggingface dataset:
Liver Fatty Acid Binding Protein: Is it an early diagnostic and prognostic marker in liver damage?
Authors: Gokcen Pinar , Cakmak Erol , Adali Gupse , Dogan Halef Okan , Yildiz Seyma Nur , Ozturk Oguzhan , Doganay Hamdi Levent , Ozdil Kamil 
Published: April 2021

Objective: The majority of the liver function tests are not specific to the liver. The histological liver damage begins before patients are diagnosed with cirrhosis and continues afterwards. Therefore, there is an increasing demand for early and specific markers that are correlated with liver damage. This study aims to investigate if serum and urinary liver fatty acid-binding protein (L-FABP) levels could be used as an early diagnostic marker of liver cirrhosis.
Material and Methods: This cross-sectional study included 30 patients with compensated liver cirrhosis, 27 patients with decompensated liver cirrhosis, and 30 healthy controls. The patients and healthy controls were tested for serum and urinary L-FABP levels.
Results: The serum and urinary L-FABP levels were higher in patients with cirrhosis than the healthy controls (both p<0.001). The cut-off value of serum and urinary L-FABP was computed as 721.78 ng/ml and 621.25 ng/ml, respectively. The sensitivity of serum and urinary L-FABP to detect cirrhosis at this cut-off was 99.8% and 98.9%. The specificity, positive predictive value, and negative predictive value of serum and urinary L-FABP at these cut-off levels were 100 %. There was no difference in terms of serum and urinary L-FABP between compensated and decompensated cirrhosis patients. Accordingly, no correlation was determined between serum/urinary L-FABP levels and cirrhosis complications.
Conclusion: L-FABP increases in serum and urine in response to hepatocyte damage that can result in liver fibrosis. We demonstrated that patients with liver cirrhosis had high L-FABP levels. L-FABP may be used as a predictive non-invasive marker of cirrhosis as it can be detected before the clinical symptoms of liver damage.
How does smartphone usage affect the severity of neck pain, neck-pain related disability, and cervical lordosis? A pilot study
Authors: Cankurtaran Damla , Aykin Yigman Zeynep , Yigman Fatih , Celik Gulnur 
Published: April 2021

Objective: Long-term and repetitive use of smartphones may cause musculoskeletal symptoms such as neck pain. This pilot study aimed to examine the effect of smartphone usage on neck pain, disability, and cervical lordosis.
Material and Methods: Seventy-eight patients were enrolled in this cross-sectional pilot study. The level of smartphone use was evaluated with the Smartphone addiction scale-short version (SAS-SV). Neck Bournemouth Questionnaire (NBQ), Neck Disability Index (NDI), and 100 mm Visual Analog Scale (VAS) were used to assess pain and disability. Cervical lordosis angle was measured using the Cobb method.
Results: A positive significant correlation with low correlation coefficient (r= 0.277, p=0.014; r: 0.295, p=0.009) was determined between SAS-SV and NBQ, and NDI. However, no correlation was found between SAS-SV and cervical lordosis angle (p>0.05). When applying simple linear regression modeling to predict neck pain severity, the SAS-SV total score alone explained 7.7% of the variance of the NBQ and 9.0% of the variance of the NDI total score.
Conclusion: We concluded that it would be beneficial to question the frequency and position of smartphone use, to recommend to use it less, and to avoid prolongation in neck flexion for patients with chronic neck pain.
The Antibiotic Susceptibilities of Methicilline-Resistant Staphylococcus aureus Strains Isolated From Various Clinical Samples
Authors: Özbek Erdal , Temiz Hakan , Özcan Nida , Akkoc Hasan 
Published: April 2021

Objective: In this study, it was aimed to determine the in vitro susceptibilities of Methicillin-Resistant Staphylococcus aureus (MRSA) strains to fluoroquinolone, linezolid, tigecycline, and quinupristin/dalfopristin as well as the macrolide-lincosamide-streptogramin B (MLSB) resistance phenotype.
Materials and Methods: A total of 94 MRSA strains isolated from various clinical samples in our hospital laboratory between January 2020 and September 2020 were included. The in-vitro susceptibilities of MRSA strains against fluoroquinolone, linezolid, tigecycline, and quinupristin/dalfopristin were determined by Kirby-Bauer disc diffusion assay according to The European Committee on Antimicrobial Susceptibility Testing (EUCAST). The E test assay was used for evaluation of tigecycline susceptibility. The D-zone test was performed with erythromycin (15 μg) and clindamycin (2 μg) discs to determine the MLSB resistance. Besides, bacterial identification, antibiotic susceptibility tests including methicillin resistance and MLSB phenotype determination were performed by using VITEK 2 Gram-positive diagnostic kits (Bio-Mérieux/France).
Results: Results: Among 94 MRSA strains included, resistance rates to ciprofloxacin, moxifloxacin, tigecycline, and quinupristin/dalfopristin were found as 71% (67 isolates) 64% (60 isolates), 17% (16 isolates), and 2% (2 isolates), respectively. Resistance was not detected for linezolid. A total of 36 (49%) isolates showed cMLSB resistance phenotype, while 18(19%) had iMLSB resistance. The methicillin susceptibility (MS) phenotype – strains resistant to erythromycin and susceptible to clindamycin- was not detected.
Conclusion: Very little resistance was found to linezolid, quinupristin/dalfopristin and tigecycline. Therefore, these antibiotics may be beneficial for the proper treatment of infections caused by MLSB-resistant isolates.
The Effect of Product Innovation on Interest with Satisfaction as Mediation
Authors: Setiobudi Auditia 
Published: April 2021

In the future, the food and beverage industry is very promising for industry players due to the trend growth of the food and beverage industry in Indonesia. The food and beverage business is starting to grow rapidly in Indonesia so that it attracts many people to innovate. One form of innovation is the frozen food industry. This study aims to determine the effect of product innovation on repurchase interest by looking at consumer satisfaction as a mediating effect on the frozen food industry. The population in this study were 147 people who were frozen food consumers. Sei. By using a purposive sampling approach and using the Slovin formula, it was determined that the number of samples in this study were 108 respondents. The results of this study indicate that product innovation has a positive and significant effect on customer satisfaction. Product innovation and customer satisfaction have a significant effect on repurchase interest. Consumer satisfaction can mediate the effect of product innovation on consumer repurchase interest.
Keywords: Product Innovation; Consumer Satisfaction; Repurchase Interest; Mediation; frozen food.
Pengaruh kemandirian belajar terhadap hasil belajar matematika siswa SMP di Balikpapan
Authors: Susilo Ganjar , Pertiwi Andi Bunga Wali Sari 
Published: April 2021

Tujuan penelitian ini untuk mengetahui pengaruh kemandirian belajar terhadap hasil belajar matematika siswa kelas VII SMP Negeri 9 Balikpapan. Teknik pengambilan sampel menggunakan teknik random sampling dengan menggunakan rumus Slovin. Teknik pengumpulan data pada penelitian ini dengan menggunakan tes hasil belajar matematika dan kuesioner kemandirian belajar. Teknik analisis menggunakan analisis regresi sederhana dengan menggunakan uji asumsi klasik, normalitas, linieritas, dan heteroskedastisitas, selanjutnya di uji hipotesis penelitian dengan menggunakan uji t. Hasil analisis data menggunakan uji t diperoleh nilai Sig. diperoleh 0,000 < nilai taraf signifikan (α) yaitu 0,05 sehingga dapat diketahui terdapat pengaruh kemandirian belajar matematika terhadap hasil belajar matematika kelas VII SMP Negeri 9 Balikpapan, dengan pengaruhnya sebesar 76,8% yang ditunjukkan dari perhitungan koefisien determinasi (R2), dan sisanya sebesar 23,2% dipengaruhi oleh variabel-variabel lainnya.
Mermaid syndrome associated with VACTERL-H syndrome
Authors: Kitova Tanya T. , Uchikova Ekaterina H. , Uchikov Peter A. , Kitov Borislav D. 
Published: April 2021

Mermaid syndrome or sirenomelia is an extremely rare congenital malformation with an incidence between 1.5 and 4.2 per 1,000,000 pregnancies. Association of mermaid syndrome with VACTERL-H syndrome is extremely rare, with only two cases reported so far in the literature. We present a new case of type I sirenomelia associated with VACTERL-H syndrome and review the relevant literature.&nbsp;
A 15-year-old female patient was admitted to the Department of Pathological Pregnancy at St George University Hospital, Plovdiv with progredient abortion during her first pregnancy. She had low socioeconomic status, negative history of concomitant diseases and addictions. The patient avoided prophylactic intake of folic acid during her pregnancy. Prenatal ultrasound found a malformative fetus. Consequently, magnetic resonance imaging was performed which established the presence of hydrocephalus and defects in the lower part of the spine. These pathological findings indicated interruption of pregnancy at 20 weeks of gestation. The fetopathological examination found sirenomelia type I associated with myelomeningocele, hydrocephalus, anal imperforation, single umbilical artery, bilateral renal and ureteric agenesis, bladder agenesis, tracheo-esophageal fistula, agenesis of external genitals, monkey fold of the left palm of the hand, also known as VACTERL-H syndrome.
Our case demonstrates that mermaid syndrome and VACTERL-H syndrome represent different manifestations of a single pathological process that results in disorders of the blastogenesis at different stages during embryonic development.&nbsp;
Écritures de soi, Écritures des limites
Authors: Chocron Michael 
Published: April 2021

Le Papotin est un atelier artistique et culturel visant à produire un journal atypique écrit par des adolescents et adultes présentant des troubles autistiques ou apparentés. Cette médiation présente comme particularité d’offrir aux participants un cadre où il est possible « d’écrire par la parole ». Pour se faire, le dispositif mis en place s’appuie sur ce qui pourrait se comprendre comme la mise en jeu d’un témoin interne pour le groupe des rédacteurs. Partant de ce qui est observé dans le cadre de cet atelier et des travaux autobiographiques d’auteurs se revendiquant du diagnostic d’autisme, je proposerai une analyse de ce dispositif indiquant comment celui-ci soutient les rédacteurs dans leur travail d’écriture. Mais cela sera également l’occasion d’appréhender comme le fonctionnement psychique d’un tel groupe permet d’envisager des propositions théoriques plus générales concernant la clinique groupale.
PREVALENCE AND MOLECULAR CHARACTERIZATION OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE (G6PD) DEFICIENCY IN FEMALES FROM PREVIOUSLY MALARIA ENDEMIC REGIONS IN NORTHEASTERN THAILAND AND IDENTIFICATION OF A NOVEL G6PD VARIANT
Authors: Dechyotin Sumalai , Sakunthai Kittipong , Khemtonglang Noppmats , Yamsri Supawadee , Sanchaisuriya Kanokwan , Kitcharoen Kriengkrai , Kitcharoen Suttiphan 
Published: April 2021

Introduction: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common X-linked enzymopathy, highly prevalent in areas where malaria is or has been endemic. Prevalence of G6PD deficiency and characterization of G6PD variants in females from previously malaria endemic areas of northeast Thailand remain unstudied.
Methods: Prevalence of G6PD deficiency was determined by a fluorescent spot test (FST) and multiplex allele specific (AS)- and restriction fragment length polymorphic (RFLP)-PCR developed for detection of common G6PD variants in the Thai population.
Results: Prevalence of G6PD deficiency in female samples (n = 355) was 18% by FST and 27% by PCR-based genotyping. The most common variant was G6PD Viangchan (54%), followed by G6PD Canton (11%) and G6PD Union (11%); in addition, a novel heterozygous variant, G6PD Khon Kaen (c.305T>C, p.F102S located in the coenzyme-binding domain), was identified. The majority (75%) of G6PD activities of heterozygotes were within the intermediate deficiency range (30-80% of median normal enzyme activity).
Conclusion: High prevalence of G6PD deficiency was present in females from northeast Thailand, the majority being due to heterozygosity of G6PD variants. The findings will have a bearing on an inclusion of primaquine in antimalarial-based policies for malaria elimination in populations with high prevalence in G6PD deficiency.
Parental Stress and Parenting during COVID-19 Pandemic in Pakistan
Authors: Imran Nazish , Sharif Muhammad Imran , Iqtadar Somia , Javed Afzal , Azeem Muhammad Waqar 
Published: April 2021

Objectives:
As COVID-19 spreads around the globe, parents are being presented with new challenges to meet their children needs. We investigated parental stress and its impact on their parenting practices during COVID-19 outbreak in Lahore, Pakistan.

Methods:
Following ethical approval, using web-based cross-sectional survey, data were collected in April 2020–May 2020. Symptoms of depression and anxiety were assessed among parents by the patient health questionnaire and generalized anxiety disorder scale. Respondents also reported on parenting practices and emotional and behavior changes noticed in their children.

Results:
Three hundred and fifty-five parents participated in the survey with a mean age of 35.3 years (standard deviation = 8.2) with 55% having at least one child between the ages of 1 and 5 years and 9% had children with special needs. The prevalence of depressive symptoms and anxiety was 25.6% and 21.6%, respectively. A significant proportion (77%) of parents were concerned about the outbreak fearing about family/self-being infected, losing love ones, and financial difficulties. Fifty percent of participants reported more than usual use of consequences (shouting at children, taking privileges away, and slapping child) in the past 1 month. However, the positive impact of parents spending more time with their children was also reported. Unhealthy eating and sleeping patterns (24.5%), irritability (21.1%), anxiety (16.3%), and aggression (14.6%) were the most common behavior and emotional problems noticed in children.

Conclusions:
Parental stress observed during COVID-19 outbreak can adversely impact the parenting practices and child's mental health. Provision of effective strategies to support parents to care for children is urgently needed.
Nikotin Menyebabkan Osteoporosis
Authors: Nilawati Nina 
Published: April 2021

Pada sebagian besar perokok, seringkali ditemukan adanya osteoporosis tulang alveolar. Dari beberapa penelitian telah diketahui terdapat hubungan antara merokok dengan jumlah mineral dan sel sel dalam kandungan tulang. Bahan utama rokok adalah tembakau yang mengandung nikotin. Karena itu untuk mengetahui pengaruh merokok terhadap tulang alveolar, salah satu cara yang dapat dilakukan adalah dengan meneliti nikotin. Penelitian ini bertujuan untuk mengetahui bagaimana nikotin dapat menyebabkan osteoporosis pada tulang alveolar. Penelitian ini adalah penelitian eksperimental dengan disain post-test control group yang dilakukan pada 16 ekor kelinci New Zealand secara random. Grup 1 (8 ekor), sebagai kelompok kontrol dan grup 2 (8 ekor), sebagai kelompok perlakuan. Pada kelompok perlakukan dilakukan injeksi larutan nikotin selama 1 minggu dengan dosis nikotin sebesar 2,5 mg/kg BW/hari. Pengamatan dilakukan pada minggu pertama dengan mengukur jumlah sel osteoklas dan sel osteoblas melalui pemeriksaan histologi. Dengan analisa statistik ditemukan perbedaan yang bermakna antara kelompok perlakuan dengan kelompok kontrol (p<0,05). Pada kelompok perlakuan, menunjukkan adanya peningkatan jumlah sel osteoklas sementara sel osteoblas menurun. Nikotin dapat menyebabkan osteoporosis tulang alveolar melalui peningkatan jumlah sel osteoklas dan penurunan sel osteoblas.
TÁC ĐỘNG CỦA VIỆC THU HỒI ĐẤT NÔNG NGHIỆP ĐẾN SINH KẾ NGƯỜI DÂN TẠI DỰ ÁN KHU ĐÔ THỊ CẦU DÂU, XÃ TRÀNG SƠN, HUYỆN ĐÔ LƯƠNG, TỈNH NGHỆ AN
Authors: Quý Lê Ngọc Phương , Vân Mai Thị Khánh 
Published: April 2021

Bài báo này nhằm mục đích làm rõ quá trình thu hồi đất để phục vụ dự án khu đô thị Cầu Dâu cũng như tác động của nó đến sự chuyển đổi vốn sinh kế cho người dân địa phương, thông qua phương pháp phỏng vấn trực tiếp 80 hộ dân xã Tràng Sơn thuộc ba nhóm đối tượng bị ảnh hưởng. Kết quả nghiên cứu cho thấy, sau khi thu hồi đất để xây khu đô thị Cầu Dâu, diện tích đất nông nghiệp của các hộ dân giảm rõ rệt từ 32,6% đến 81,1% tổng diện tích. Trước thu hồi đất, khoản thu từ nông nghiệp chiếm tỷ trọng cao nhất (82,6%), nhưng sau thu hồi chỉ chiếm 38,9% trong tổng thu nhập của hộ. Hiện tại, nguồn thu nhập của các hộ gia đình được cải thiện hơn nhờ các ngành nghề lao động tự do và các hoạt động phi nông nghiệp. Sau quá trình thu hồi đất, nguồn vốn vật chất của các hộ dân cũng được cải thiện nhiều hơn. Cụ thể, từ 93% đến 100% các hộ phỏng vấn đều mua sắm được các phương tiện sinh hoạt trong gia đình như xe máy, điện thoại, tivi, tủ lạnh. Bên cạnh những hộ dân nhận được tác động tích cực từ việc thu hồi đất, một số hộ dân vẫn còn gặp phải khó khăn trong quá trình thích ứng với cuộc sống “bên ngoài đồng ruộng”. Nghiên cứu cũng cho thấy cần có những giải pháp cụ thể hơn đối với hình thức bồi thường, hỗ trợ đền bù, tái định cư từ phía Nhà nước để người dân có sinh kế bền vững sau thu hồi đất.
ABSTRACT
This paper aimed to clarify the process of land acquisition to serve the Cau Dau urban project as well as its impact on the conversion of livelihood capital of local people through direct interview method. 80 households in Trang Son commune belonged to three groups of affected people. Research results showed that after recovering land to build Cau Dau urban area, the agricultural land area of ​​households decreased significantly from 32.6% to 81.1% of the total area. Before the land acquisition, income from agriculture accounted for the highest proportion (82.6%). On the other hand, after the recovery, this figure accounted for 38.9% of total household income. At present, household income is being improved thanks to the earned money from freelance labor and non-farm activities. After the land acquisition process, the physical capital of households has been improved. Specifically, from 93% to 100% of the interviewed households could buy home appliances such as refrigerators, televisions, mobile phones, and even motorbikes. Most of the interviewed households have received positive impacts from the acquisition of agricultural land. However, the other ones have faced up difficulties in adapting to "outside the field" life.
ĐÁNH GIÁ KHẢ NĂNG SINH TRƯỞNG VÀ PHÁT TRIỂN CỦA MỘT SỐ GIỐNG HOA ĐỒNG TIỀN LÙN TẠI THÀNH PHỐ HUẾ, TỈNH THỪA THIÊN HUẾ
Authors: Đình Thục Đỗ 
Published: April 2021

Thí nghiệm thực hiện trong vụ Đông Xuân năm 2020 tại thành phố Huế, tỉnh Thừa Thiên Huế nhằm mục đích tìm hiểu đặc điểm sinh trưởng, phát triển của 6 giống hoa đồng tiền lùn (ĐT) trồng chậu gồm có 305 (màu hồng), ĐT 308 (màu vàng), ĐT 315 (màu trắng), ĐT 320 (màu đỏ thẫm), ĐT 326 (màu đỏ đô), giống đối chứng (màu đỏ tươi) đã được trồng thử nghiệm tại tỉnh Thừa Thiên Huế trong 2 năm và xác định được giống hoa đồng tiền lùn phù hợp với điều kiện sinh thái tỉnh Thừa Thiên Huế. Kết quả nghiên cứu cho thấy các giống tham gia thí nghiệm có thời gian sinh trưởng phù hợp với điều kiện địa phương (73 - 93 ngày). Các giống hoa đồng tiền lùn thí nghiệm đều có số hoa trên cây dao động từ 1,3 - 1,9 hoa, đường kính hoa đạt yêu cầu thẩm mĩ, độ bền hoa dài, màu sắc hoa đẹp phù hợp với thị hiếu người tiêu dùng trên địa bàn thành phố Huế. Trong đó có 3 giống là ĐT 308 (màu vàng), ĐT 320 (màu đỏ thẫm) và ĐT 305 (màu hồng) có các chỉ tiêu sinh trưởng phát triển tốt hơn so với các giống khác và giống đối chứng.
ABSTRACT
The experiment was carried out in the Winter-Spring crop of 2020 in Hue city, Thua Thien Hue province with the aim of understanding the growth and development characteristics of 06 potted gerbera varieties including gerbera variety 305 (pink), gerbera variety 308 (yellow), gerbera variety 315 (white), gerbera variety 320 (dark red), gerbera variety 326 (brown red), control gerbera variety (fresh red) and identifying the dwarf gerbera variety suitable for the ecological condition of Thua Thien Hue province. The results of the study showed that the varieties in the experiment had suitable duration for local conditions (73 - 93 days). The experimental dwarf gerbera varieties had the number of flowers per plant ranging from 1.3 to 1.9 flowers, the flower diameter met the aesthetic requirements, long flower durability, beautiful flower color, and general all varieties are suitable for human interests and consumption in Hue city. 3 varieties including gerbera variety 308 (yellow), gerbera variety 320 (dark red), and gerbera variety 305 (pink) had better growth and development performances than other varieties and control variety.
XÁC ĐỊNH MỘT SỐ LOÀI ĐỊCH HẠI TRÊN HÀU NUÔI TẠI ĐẦM LẬP AN, THỊ TRẤN LĂNG CÔ, HUYỆN PHÚ LỘC, TỈNH THỪA THIÊN HUẾ
Authors: Hoàng Nguyễn Việt , Thuần Đoàn Thị Ngọc , Sự Võ Văn , Thủy Nguyễn Thị Thanh , Chất Tôn Thất 
Published: April 2021

Qua quá trình điều tra cho thấy có 4 nhóm địch hại phổ biến đối với hàu nuôi ở đầm Lập An, thị trấn Lăng Cô, huyện Phú Lộc, tỉnh Thừa Thiên Huế gồm: (i) Họ vẹm (vẹm Xanh (Perna viridis), vẹm Đen (Perna sp.); (ii) Sun (Balanus sp.); (iii) Giun nhiều tơ (Polydora sp.); và (iv) các loài ăn thịt (tôm Sú - Penaeus monodon, cua Xanh - Scylla parapamosain, cá Dìa - Siganus guttatus). Vẹm Xanh (Perna viridis) và vẹm Đen (Perna sp.) giống xuất hiện nhiều vào tháng 4 - tháng 5. Sun (Balanus sp.) xuất hiện nhiều từ tháng 6 - tháng 12, địch hại còn lại xuất hiện hầu như suốt vụ nuôi. Hình thức gây hại chính của địch hại là kí sinh trong, ngoài vỏ và bám chiếm giá thể, còn các loài ăn thịt dùng các cơ quan phá vỡ vỏ hàu để ăn thịt. Tổng sản lượng hàu nuôi tại đầm Lập An là 529,5 tấn/vụ, sản lượng trung bình đạt 8,54 tấn/hộ/vụ. Nghề nuôi hàu mang lại thu nhập cao cho người dân tại đầm Lập An, lợi nhuận các hộ nuôi hàu tại đầm Lập An thu được từ 74 - 118 triệu đồng/vụ. Khi thời tiết không thuận lợi, địch hại hàu nuôi xuất hiện nhiều khi phát triển bùng phát làm giảm năng suất và sản lượng của hàu nuôi.
ABSTRACT
The investigation showed that there are 4 common harmful groups of oysters in Lap An lagoon, Lang Co town, Phu Loc district, Thua Thien Hue province, including (i) Mussel (Green mussel - Perna viridis, Black mussel - Perna sp.); (ii) Sun (Balanus sp.); (iii) Polychaete (Polydora sp.); and (iv) Predators such as Giant tiger prawn (Penaeus monodon), Mud crab (Scylla parapamosain), Orange spotted spinefoot (Siganus guttatus). Green mussel (Perna viridis), Black mussel (Perna sp.), the breed mainly appears in April - May. Sun (Balanus sp.) mostly appears from June to December, the remaining predators nearly appear during the crop. The main harmful forms of natural enemies are to live as parasites inside, outside of the shell, and clinging to the planktons, while the predators use some of their body parts to break the oysters’ outer shell. The total production of cultured oysters in Lap An lagoon is 529.5 tons/crop, the average yield is 8.54 tons/household/crop. Oyster farming brings high income for people in Lap An lagoon, oyster farming households in Lap An lagoon earn from 74 to 118 million VND/crop. When the weather is unfavorable, the predators of cultured oysters sometimes appear to grow out, reducing the productivity and yield of cultured oysters.