bluuebunny/crossref_metadata_2025_split huggingface dataset:
Algae bioprocess to deal with cosmetic chemical pollutants in natural ecosystems: A comprehensive review
Authors: Mishra Prabhakar , Kiran N. S. , Romanholo Ferreira Luiz Fernando , Mulla Sikandar I. 
Published: December 2021

AbstractElevated demand and extensive exploitation of cosmetics in day‐to‐day life have hiked up its industrial productions worldwide. Organic and inorganic chemicals like parabens, phthalates, sulfates, and so forth are being applied as constituents towards the formulations, which tend to be the mainspring ecological complication due to their enduring nature and accumulation properties in various sections of the ecosystem. These cosmetic chemicals get accrued into the terrestrial and aquatic systems on account of various anthropogenic activities involving agricultural runoff, industrial discharge, and domestic effluents. Recently, the use of microbes for remediating persistent cosmetic chemicals has gained immense interest. Among different forms of the microbial community being applied as an environmental beneficiary, algae play a vital role in both terrestrial and aquatic ecosystems by their biologically beneficial metabolites and molecules, resulting in the biobenign and efficacious consequences. The use of various bacterial, fungal, and higher plant species has been studied intensely for their bioremediation elements. The bioremediating property of the algal cells through biosorption, bioassimilation, biotransformation, and biodegradation has made it favorable for the removal of persistent and toxic pollutants from the environment. However, the research investigation concerned with the bioremediation potential of the algal kingdom is limited. This review summarizes and provides updated and comprehensive insights into the potential remediation capabilities of algal species against ecologically hazardous pollutants concerning cosmetic chemicals.
Inventory and assessment of pH in cropland and grassland soils in Germany#
Authors: Müller Theresia Sophia , Dechow René , Flessa Heinz 
Published: December 2021

AbstractBackgroundSoil pH is one of the key factors affecting soil fertility. For optimal plant growth on agricultural land, suitable liming management is recommended. The basis of appropriate soil pH management in agriculture is provided by recommendations on site‐specific optimum pH ranges and lime application.AimsThis study determined the current variability of soil pH of cropland and grassland in Germany, analysed the factors associated with this variability, evaluated pH management on German agricultural land and developed a national map of current pH values in agricultural soils.MethodsThe study mainly focused on the topsoil layers of 2197 cropland sites (0–30 cm) and 812 permanent grasslands sites (0–10 cm) in the German Agricultural Soil Inventory, but reports soil pH (CaCl2) down to 50 cm. Random forest models were applied to identify environmental and management factors related to soil pH and develop a map of pH values in agricultural topsoils in Germany. The current pH status of the sampled sites was classified in accordance with German lime requirement recommendations.ResultsThe soil pH of both land‐use types showed a bimodal distribution, with peaks at pH 6.1 and 7.3 for cropland and pH 5.0 and 7.1 for grassland. Soils with pH <5 were mainly found on sandy soils in northern Germany and acidic parent material in southern Germany. Alkaline soils predominated in central and southern Germany on loess and carbonate‐rich material. The carbonate content was the major factor explaining soil pH variability, but its effect was restricted to pH values >6. Only 35.4% of the cropland sites and 23.9% of the grassland sites were within the recommended optimum pH range. The percentage of sites below the recommended pH range was greater for grassland than for cropland (52.0% and 41.0%, respectively).ConclusionsSoil pH of German agricultural land is influenced by natural factors and pH management. The first national inventory of soil pH showed that many agricultural soils exhibited pH values lower than those recommended. More conscientious pH management could help improve soil fertility and crop yield. This should be based on the regular topsoil pH analysis conducted by most farmers every five years, together with the determination of plant‐available potassium and phosphorus in soils.
Using the cobweb classification system as a digital location system for the neurologic compression in cervical degenerative disease
Authors: Xiong Yang , Yang Ying‐Li , Yu Xing , Wang Feng‐Xian , Yang Yong‐Dong , Zhao Ding‐Yan , Zhao He , Li Chuan‐Hong , Yang Kai‐Tan 
Published: December 2021

AbstractObjectiveTo provide the cobweb classification system (CCS) for the precise digital location and description of the neurological compression in cervical degenerative disease (CDD), and the reliability and the clinical subgroup analysis of the system were tested and analyzed.MethodsThe CCS consisted of three parts: compression zones (1‐12), degrees (a, b) and ossification (s, m, h). Computerized tomography (CT) and magnetic resonance imaging (MRI) images from 238 CDD patients were reviewed. All compression cases were classified by five independent reviewers with varied clinical experience in spine surgery. The reliability of the CCS was tested by calculating the kappa (κ) statistics value. Finally, 74 patients with anterior cervical surgery treatment were enrolled for the clinical subgroup analysis.ResultsFor the small compression, including single and double compression zones, there was a good interobserver reliability between the reviewers (κ coefficient = .855, P < .001). For the large compression with three or more involved zones, there was a fair reliability between the reviewers (κ coefficient = .696, P < .001). The whole intraobserver reliability was good (κ coefficient = .923, P < .001). For clinical practice, the operative time in the large compression and the m/h group was significantly longer than the small compression and the s group, respectively (P < .05), and the blood loss in the m/h group was significantly increased as well (P < .01). Though the preoperative Japanese Orthopedic Association score in Group b was lower than Group a (P < .05), all patients had achieved significant clinical improvement at last follow‐up.ConclusionsThe CCS can be used to provide detailed and objective descriptions of the location, extent, and severity of neurological compressions in CDD with satisfactory reliability. Surgeons should pay more attention to the patient with large zone, degree b, and ossification compression, because the operation may be more challenging.
Ternary Transition Metal Dichalcogenides for High Power Vector Dissipative Soliton Ultrafast Fiber Laser
Authors: Li Lu , Pang Lihui , Wang Rongfeng , Zhang Xiaogang , Hui Zhanqiang , Han Dongdong , Zhao Feng , Liu Wenjun 
Published: December 2021

Abstract2D ternary transition metal dichalcogenides (TMDCs) have been studied widely by researchers from the fields of nanotechnology to materials science because of the extraordinary chemical/physical characteristics, and significant potential in nanoscale device applications. Here, the application of NbxRe(1−x)S2 nanosheets in ultrafast photonics is studied. The few‐layer NbxRe(1−x)S2 nanosheets are fabricated through liquid phase exfoliation method and a NbxRe(1−x)S2‐microfiber device is constructed by depositing these nanosheets onto the tapered region of a microfiber. After incorporating the NbxRe(1−x)S2‐microfiber saturable absorber (SA) into a net positive dispersion Er‐doped fiber (EDF) laser cavity, the generation of stable dissipative soliton pulses with a pulse duration of 1.03 ps proved as polarization‐locked vector solitons upon further study. With pump power growing to 900 mW, the average output power increases to 116.9 mW without pulse splitting. Besides, the pulse width can be compressed to 149.6 fs outside the cavity by using a single‐mode fiber. Compared with previous works based on 2D materials‐based saturable absorbers, the NbxRe(1−x)S2‐based mode‐locked fiber laser proposed herein, reveals superior comprehensive performance.
Laser Frequency Combs with Fast Gain Recovery: Physics and Applications
Authors: Piccardo Marco , Capasso Federico 
Published: December 2021

AbstractThe dynamics of semiconductor lasers with fast gain is generally considered to suppress amplitude modulation, resulting in a frequency‐modulated output. Since their first demonstration of frequency comb operation, quantum cascade lasers—ideal representatives of this class of lasers with fast gain dynamics—were indeed shown to emit frequency‐modulated combs. The understanding of these frequency comb regimes has progressively evolved, being refined from simpler arguments to more advanced theories, considering the role of Kerr nonlinearity and linewidth enhancement factor. By now, the traditional frequency‐modulated combs are rather well understood in quantum cascade lasers, but new types of frequency combs have emerged, reopening interesting physics questions in these lasers. Recent advancements on two open frontiers will be discussed: harmonic frequency combs, characterized by mode skipping of many free spectral ranges, and spatiotemporal structures with solitonic features, recently reported in unidirectional ring cavities. These new types of frequency combs open technological and fundamental perspectives, sprouting new interest in quantum cascade lasers.
Graph‐like spaces approximated by discrete graphs and applications
Authors: Post Olaf , Simmer Jan 
Published: December 2021

AbstractWe define a distance between energy forms on a graph‐like metric measure space and on a suitable discrete weighted graph using the concept of quasi‐unitary equivalence. We apply this result to metric graphs, graph‐like manifolds (e.g. a small neighbourhood of an embedded metric graph) or pcf self‐similar fractals as metric measure spaces with energy forms associated with canonical Laplacians, e.g., the Kirchhoff Laplacian on a metric graph resp. the (Neumann) Laplacian on a manifold (with boundary), and express the distance of the associated energy forms in terms of geometric quantities. In particular, we show that there is a sequence of domains converging to a pcf self‐similar fractal such that the corresponding (Neumann) energy forms converge to the fractal energy form. As a consequence, the spectra and suitable functions of the associated Laplacians converge, the latter in operator norm.
Sertaconazole provokes proapoptotic autophagy via stabilizing TRADD in nonsmall cell lung cancer cells
Authors: Zhang Wenhui , Zhou Li , Qin Siyuan , Jiang Jingwen , Huang Zhao , Zhang Zhe , Zhang Xiyu , Shi Zheng , Lin Jie 
Published: December 2021

AbstractNonsmall cell lung cancer (NSCLC) is one of the most commonly diagnosed and lethal cancers characterized by relatively low overall cure and poor survival rates with great challenge for consistent effective clinical treatment. Here we demonstrated that the antifungal sertaconazole displays potent anti‐NSCLC effect by promoting apoptosis in vitro and in vivo. Further studies found that sertaconazole induces complete autophagic flux, which contributes to sertaconazole‐induced apoptosis and subsequent growth suppression in NSCLC cells. Further studies demonstrated that sertaconazole provokes TNF receptor type 1 associated death domain protein (TRADD) expression via stabilizing it from ubiquitination‐mediated degradation, which results in Akt dephosphorylation and thereby triggers proapoptotic autophagy in NSCLC cells. Moreover, we found that TRADD suppression reverses sertaconazole‐induced proapoptotic autophagy and relieves growth suppression, indicating the vital role of TRADD‐regulated proapoptotic autophagy in the anti‐NSCLC activity of sertaconazole. In summary, our findings suggest that sertaconazole could be a highly promising anti‐NSCLC drug by triggering proapoptotic autophagy via stabilizing TRADD, which may provide a new potential therapeutic option for patients with NSCLC.
Functional nanoparticles in electrospun fibers for biomedical applications
Authors: Saiding Qimanguli , Cui Wenguo 
Published: December 2021

AbstractElectrospinning provides a facile route for generating fibers with diameters ranging from hundreds of nanometers to several micrometers. This technology has been widely explored in many biomedical areas including drug delivery systems (DDS), disease diagnosis and treatment, biosensing as well as tissue engineering. However, there are still existing challenges for electrospinning fibers in achieving complex regenerative or reconstructive processes through pure surface modification or simple drug loading. With the rise of nanotechnology, functional nanoparticles (NPs) made by various materials rapidly emerged in tissue engineering and regenerative medicine. Due to the objective size difference between NPs and electrospun fibers, doping NPs into electrospun nanofibers makes it possible to produce functional fibers having the inherent merits of both the guest NPs and the host fibers. In this review, we focus on the recent progress in preparing nanoparticle bearing electrospun hybrid fibers for biomedical applications. The organic, inorganic and mesoporous nanoparticles combined with electrospun nanofibers for different biological scenarios with several notable examples were systematically reviewed. Then, we finish with challenges and future perspectives of electrospun hybrid fiber materials for drug delivery and regenerative medicine.
Intraventricular topotecan in the successful treatment of recurrent CNS pleuropulmonary blastoma
Authors: Shim Jenny , Reisner Andrew , Esiashvili Natia , Rapkin Louis , Olson Thomas 
Published: December 2021

AbstractPleuropulmonary blastoma (PPB) is a rare pediatric tumor of the pleura and pulmonary mesenchyme, associated with pathogenic germline DICER1 mutations. Although the most common site of metastasis is the central nervous system (CNS), patients with CNS metastasis have dismal outcome. We report a case of a patient presenting with type II PPB and intracranial and bone metastases. We describe a multimodal therapy approach and highlight the use of intraventricular topotecan for isolated CNS recurrence. In addition, a new pathogenic germline mutation heterozygous for the c.1234delT of DICER1 was identified. Patient remains in remission 3 years after recurrence.
Boredom proneness and core self‐evaluation as mediators between loneliness and mobile phone addiction among Chinese college students
Authors: Li Xinwei , Zhou Hui , Xiao Weilong 
Published: December 2021

AbstractAlthough loneliness is related to mobile phone addiction among college students, little is known about the mediating mechanisms underlying this association. on the basis of the Interaction of person–affect–cognition–execution model for addictive behaviors, self‐verification theory, and previous results of empirical studies, the present study examined the mediating roles of boredom proneness and core self‐evaluation in the relationship between loneliness and mobile phone addiction among college students. A sample of 1300 Chinese college students (mean age = 20.40 years, SD = 0.97) were recruited to complete a series of questionnaires measuring loneliness, boredom proneness, core self‐evaluation, and mobile phone addiction. These results showed that loneliness was positively correlated with mobile phone addiction; boredom proneness and core self‐evaluation partially mediated this relationship when they operate in a parallel fashion. The relationship between loneliness and mobile phone addiction was mediated totally by boredom proneness and core self‐evaluation when they operate sequentially. These findings help us to better understand the relationship between loneliness and mobile phone addiction and provide implications for the prevention and intervention of mobile phone addiction.
Precise Preparation of Various Morphological Silver Sulfide Nanostructures, Investigation of Formation Mechanism, and Comparative Study of Photothermal Performance for Cancer Treatment
Authors: Gao Minjie , Du Jiyuan , Han Zehua , Wang Zhihua , Zhao Yanbao , Zou Xueyan , Sun Lei 
Published: December 2021

AbstractAs a bio‐nanomaterial with low toxicity, Ag2S has attracted more and more attention due to its intensive absorption of near‐infrared (NIR) light. Meanwhile, it has become a novel and excellent photothermal transduction agent due to its local surface plasma resonance effect. However, little research is conducted with respect to the influences of factors such as shapes on photothermal property. In this paper, a novel and convenient strategy is proposed to prepare three shapes of Ag2S (i.e., hollow nanospheres, nanoplates, and porous nanoplates), and their formation mechanisms are revealed through various characterizations. Furthermore, the in vitro capabilities of hollow Ag2S nanospheres are compared with nanoplates and porous nanoplates as photothermal transduction agents for theranostic applications. All these Ag2S nanostructures can absorb and convert 808 nm NIR light into heat. Among them, porous Ag2S nanoplates possess the highest photothermal conversion efficiency, whereas hollow Ag2S nanospheres have the maximum temperature difference. In addition, hollow Ag2S nanospheres exhibit the highest cellular uptake and the best treatment effect. Combined, it can be concluded that hollow Ag2S nanospheres are promising candidates for cancer treatment.
Mechanical Properties of HTPB Propellant under Shear Loading at Low Temperature
Authors: Wang Jia‐xiang , Qiang Hong‐fu , Wang Zhe‐jun 
Published: December 2021

AbstractA new type of shear loading fixture and tensile testing machine with a refrigeration system was utilized to conduct Hydroxyl‐terminated polybutadiene (HTPB) propellant low strain rate (0.01∼1.00 s−1) shear loading tests at low temperature (223 K∼298 K). The shear strength and shear modulus of the HTPB propellant under different loading conditions were studied, and the master curves of the shear mechanical properties were constructed. It is found that the shear strength of HTPB propellant increases with increasing of shear strain rate and decreasing of temperature. The change of shear strength with temperature and strain rate conforms to the linear double logarithmic relationship. The initial shear modulus has a good linear double logarithmic relationship with the strain rate but changes nonlinearly with the logarithmic temperature. The shift factor of HTPB propellant shear strength and initial shear modulus changes exponentially with temperature after taking logarithm. The master curve of the initial shear modulus of HTPB propellant shows an “S”‐shaped change trend, and a linear equation is used to fit the master curve of shear strength to obtain a better fitting effect.
Design, Synthesis and In Vivo Cardiovascular Evaluation of Some Novel Aryloxy Propanol Amino Acid Derivatives
Authors: Soltani Hekmat Ava , Farjam Mojtaba , Javanmardi Kazem , Behrouz Somayeh , Zarenezhad Elham , Soltani Rad Mohammad Navid 
Published: December 2021

AbstractThe design, synthesis and biological evaluation of some aryloxy propanol amino acid derivatives have been described. Synthetic pathways is consisted of the reaction of phenol derivatives with epichlorohydrin and/or epibromohydrin produced the various O‐phenol ether adducts. In continue, the reaction of amino acid with O‐phenol ether adducts generated the new class of β‐blocking agents. The products were evaluated for their cardiovascular property. The 2‐kidney‐1‐clip method was used to induce renovascular hypertension in rats. New analogues of propranolol were evaluated in order to find the most appropriate ones for reducing the hypertension. Our results showed that compound 4 d [i. e.: (2‐hydroxy‐3‐phenoxypropyl) glycine] was effective in blood pressure lowering, even lower than propranolol as a standard drug. All the modelling study was performed at physiological pH (pH∼7.0–7.4).The MEP and docking analysis have shown the appropriate fitting of (2‐hydroxy‐3‐phenoxypropyl) glycine in human β2‐adrenergic receptor active site.
Innovative Synthesis of PANI/Cu2O Nanocomposite and Its Antibacterial Properties**
Authors: Zhang Mengmeng , Han Sha , Niu Xiaohui , Li Hongxia , Zhang Deyi , Fan Haiyan , Wang Kunjie 
Published: December 2021

AbstractTo fight various bacteria‐caused inflammations and overcome drug resistance, the present work develops a simple in‐situ growth method to synthesize Cu2O nanoparticles involved nanocomposite using polyaniline (PANI) matrix. The morphology of the as prepared composite was characterized by Scanning Electron Microscope (SEM) and X‐ray Diffraction Spectroscopy (XRD), and the molecular structure was identified using Fourier‐Transforms Infrared FT‐IR, X‐ray Photoelectron Spectroscopy (XPS), and UV‐Visible Spectroscopy (UV‐Vis). The antibacterial properties of PANI/Cu2O nanocomposite were tested against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), and Methicillin‐resistant Staphylococcus aureus (MRSA). The combination of PANI and Cu2O indicated a synergistic antibacterial effect. The analysis of the antimicrobial mechanism revealed that the positive charge released from the nanocomposite takes the main responsibility. This work provides new ideas for the design of metal oxide and polymer nanocomposites and the development of antibiotics.
Copper‐Catalyzed Cleavage of Aryl C(OH)−C Bonds to Access Aryl Nitriles
Authors: Zheng Yi , Liu Wenbo , Ren Yun‐Lai , Guo Yinggang , Tian Xinzhe 
Published: December 2021

AbstractIt was found that aryl nitriles could be synthetized by cleavage of aryl C(OH)−C bonds in the presence of oxygen gas, (NH4)2CO3 and Cu(OAc)2. The present protocol allowed various secondary aryl alcohols to undergo the present transformation to give aryl nitriles in low to high yields. Lignin‐related β‐O‐4 and β‐1 linkages could be converted to benzonitriles under the present conditions, which provides an avenue to obtain value nitrile products via fragmentation of lignin.
Large‐Grain Spanning Monolayer Cu2ZnSnSe4Thin‐Film Solar Cells Grown from Metal Precursor
Authors: Li Jianjun , Huang Jialiang , Cong Jialin , Mai Yaohua , Su Zhenghua , Liang Guangxing , Wang Ao , He Mingrui , Yuan Xiaojie , Sun Heng , Yan Chang , Sun Kaiwen , Ekins‐Daukes Nicholas J. , Green Martin A. , Hao Xiaojing 
Published: December 2021

AbstractThe persistent double layer structure whereby two layers with different properties form at the front and rear of absorbers is a critical challenge in the field of kesterite thin‐film solar cells, which imposes additional nonradiative recombination in the quasi‐neutral region and potential limitation to the transport of hole carriers. Herein, an effective model for growing monolayer CZTSe thin‐films based on metal precursors with large grains spanning the whole film is developed. Voids and fine grain layer are avoided successfully by suppressing the formation of a Sn‐rich liquid metal phase near Mo back contact during alloying, while grain coarsening is greatly promoted by enhancing mass transfer during grain growth. The desired morphology exhibits several encouraging features, including significantly reduced recombination in the quasi‐neutral region that contributes to the large increase of short‐circuit current, and a quasi‐Ohmic back contact which is a prerequisite for high fill factor. Though this growth mode may introduce more interfacial defects which require further modification, the strategies demonstrated remove a primary obstacle toward higher efficiency kesterite solar cells, and can be applicable to morphology control with other emerging chalcogenide thin films.