bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidences Of Nasal Septal Deviation And Its Effect On Surgical Success In Patients With Congenital Nasolacrimal Dacryostenosis
Authors: özdemir fatma esin , Bezgin selin Üstün , Karademir Zeliha 
Published: April 2021

Abstract
OBJECTIVE: An investigation of incidences of nasal septal deviation (NSD) and its effect on surgical success in patients with congenital nasolacrimal dacryostenosis (CNLDO).METHODS: A retrospective review was made of the medical records of patients who presented to the ophthalmology clinic due to epiphora, were diagnosed with CNLDO and underwent probing. The diagnosis was established by history, clinical examination, and fluorescein disappearance test (FDT)1. Patients with FDT grade 2 and 3 underwent surgery. Success was defined as postoperative FDT grade 0–1. The patients were assessed in terms of gestational week, birth weight, type of delivery, nasal endoscopic examination findings (presence of NSD), time of surgery, treatments received, recurrence and complications.RESULTS: The study comprised 72 eyes of 58 patients who were diagnosed with CNLDO and underwent surgical treatment. Of the patients, 44 (75.86%) had unilateral, and 14 (24.14%) had bilateral CNLDO; 41 (56.94%) were female and 31 (43.06%) were male. The mean gestational age at birth was 38.01 weeks (32–41 weeks), the mean birth weight was 3321.25 (2020–4500 g), the number of cases delivered by cesarean section was 40 (55.56%), and 32 (44.44%) were vaginal deliveries. There were 13 (18.06%) patients with detected NSD after endonasal examination and 59 (81.94%) patients with normal endonasal examination in the Otorhinolaryngology (ORL) department. The time of surgery was 10 –34 months (mean: 19.06 months, SD: 5.73), the length of follow-up was 6–16 months (mean: 9.90 months, SD: 2.58). The rate of probing success was 80.6% (58 eyes), and there was recurrence in 19.4% (14 eyes).The success rate of the probing did not statistically significantly differ by gender (p=0.323), the mean birth week (p=0.123), the mean birth weight (p=0.186), the involved eye (p=0.891), the type of delivery (p=0.891), the mean length of follow-up (months) (p=0.701), the mean month of surgery (p=0.607), and the side of NSD (p=0.853). The incidence of NSD was statistically significantly higher in the group in which the probing failed, than in the group in which the probing was successful (p=0.004).CONCLUSION: NSD was identified in 18% of the patients who were diagnosed with CNLDO and underwent surgery. The incidence of NSD was significantly higher in the group where the probing procedure failed. Pre-treatment nasal endoscopy is important for the treatment planning and prognosis of CNLDO patients.
Predicting Running Time of Aerodynamic Jobs in HPC System by Combining Supervised and Unsupervised Learning Method
Authors: Wang Hao , Dai Yi-Qin , Yu Jie , Dong Yong 
Published: April 2021

Abstract
Improving resource utilization is an important goal of high-performance computing systems of supercomputing centers. In order to meet this goal, the job scheduler of high-performance computing systems often use backfilling scheduling to fill short-time jobs into the gaps of jobs at the front of the queue. Backfilling scheduling needs to obtain the running time of the job. In the past, the job running times are usually given by users and often far exceeded the actual running time of the job, which leads to inaccurate backfilling and a waste of computing resources. In particular, when the predicted job running time is lower than the actual time, the damage caused to the utilization of the system’s computing resources becomes more serious. Therefore, the prediction accuracy of the job running time is crucial to the utilization of system resources. The use of machine learning methods can make more accurate predictions of the job running time. Aiming at the parallel application of aerodynamics, we propose a job running time prediction framework SU combining supervised and unsupervised learning, and verifies it on the real historical data of the high-performance computing systems of China erodynamics Research and Development Center(CARDC). The experimental results show that SU has a high prediction accuracy(80.46%) and a low underestimation rate(24.85%).
In-vitro and In-silico approach for characterization of antimicrobial-peptide from probiotics against Staphylococcus aureus and Escherichia coli
Authors: Bindu Amrutha , N Lakshmidevi 
Published: April 2021

Abstract
The present aim was to determine the characteristic feature and stability of antimicrobial compound (AMC) produced by probiotic strains of Enterococcus durans MCC4243, Lactiplantibacillus plantarum (Basanym: Lactobacillus plantarum MCC4246) and Limosilactobacillus fermentum (Basonym: Lactobacillus fermentum MCC4233) against Staphylococcus aureus MTCC96 and Escherichia coli MTCC118. Growth kinetic assay revealed 24h of incubation to be optimum for bacteriocin production. Ammonium sulphate precipitation-dialysis was found to be favorable method for extraction of AMC compared to other methods employed. The partially purified compound after ion-exchange chromatography was found to be thermo-resistant upto 90°C and stable under wide range of pH. The compound was sensitive to proteinase-K, but resistant to trypsin, α-amylase and lipase. The apparent molecular weight of AMC from MCC4243 and MCC4246 was found to be 3.5KDa. PCR confirmed the presence of plantaricinA gene in MCC4246. Translated partial amino acid sequence of plnA gene of MCC4246 displayed 48 amino acid sequence which had 100% similarity with plantaricinA of Lactobacillus plantarum (WP 0036419). The sequence revealed 7 β sheets, 6 α sheets, 6 predicted coils and 9 predicted turns and functions on cytoplasm with 10.82 isoelectric point and 48.6% hydrophobicity. From the study, the amino acid sequence “KSSAYSLQMGATAIKQVKKLFKKWGW” of peptide was predicted to be responsible for antimicrobial activity.
Water Inrush and Failure Characteristics of Coal Seam Floor Over A Confined Aquifer
Authors: Cao Min , Yin Shangxian , Xu Bin 
Published: April 2021

Abstract
Failure behaviors of the floor rocks under coal seam mining in the conditions of hard magma rock roof and confined aquifer are studied. Based on the theory of rock stresses and elasticity mechanics, the combined effects of the abutment pressure induced by the hard roof and by the water pressure under the thin aquicludes of the floor rocks were considered, and a mechanical model was constructed along the strike of the working face. An analytical solution of stress distribution was derived in the floor rocks, the distributions of vertical, horizontal and shear stresses were calculated. In combination with the in-situ measurement, the results show that: 1) when the periodic pressure caused by the roof collapse occurs on the working face, and the maximum stress concentration in the floor appears at the elastic-plastic junction in the direction of the strike of the working face. With the increase of the depth of the floor, the horizontal stress coefficient tends to decrease, and the corresponding shear stress coefficient isoline shows a “symmetric spiral” distribution and propagates downward to the floor at a certain angle with the vertical direction. This causes the floor rocks to generate compression and shear or tension and shear failure. 2) when the immediate roof of coal seam is the magma rock, the abutment pressure shows a trend of a slow increase initially and then a rapid increase later. The peak value of abutment pressure appears at the location of 4 - 6 meters from the coal wall of the working face, and the concentration coefficient of the abutment pressure is between 1.4 and 1.8. 3) according to the measurement and calculation of the failure depths of the floor at different positions under the same coal seam, it is found that the maximum failure depth appears near the coal wall of the working face. The failure depth reduces by 11.6% after the floor goes through “the roof caving and re-compaction”, which causes the fractures in the floor to close and the thickness of the effective aquiclude increases. In the un-mined area of the working face, the failure depth is 55% of the maximum failure depth. 4) both the theoretical calculation and the numerical simulation show that the failure depth of the floor increases obviously under the combined action of high vertical stress and the water pressure. Under the condition that the thickness of the aquiclude is relatively thin, the water pressure of the floor and pressure intensity of the roof are the sensitive factors to affect the maximum failure depth of the floor.
Seasonal fluctuation and host species affect Tobacco ringspot virus detection
Authors: Beaver-Kanuya Eunice E , Harper S.J. 
Published: April 2021

Abstract
Tobacco ringspot virus (TRSV) is a pathogen with a wide host range that can cause disease in many perennial species. Yet detection of this virus can be insistent and unreliable, complicating disease management. In this study we asked whether seasonal effects changed the titer and distribution of the virus in Vitis vinifera, Malus domestica, and Prunus armeniaca. We developed an RT-qPCR assay and used it to monitor TRSV accumulation in leaves, stems, and roots over the course of a year. TRSV titer, and the tissues in which it accumulated, changed throughout the year in a host-specific manner which may be due to host plant growth patterns and temperature. These data will aid in determining optimal sampling time, and which tissues to collect to have confidence in diagnostic results.
Assessing and mapping wind erosion-prone areas in northeastern Algeria using additive linear model, AHP, FAHP approaches, GIS, and medium resolution multisource remotely sensed data
Authors: Mihi Ali , Benaradj Abdelkrim 
Published: April 2021

Abstract
Wind erosion is one of the most severe environmental problems in arid, semi-arid and dry sub-humid regions of the planet. This dissertation aimed to identify areas sensitive to wind erosion in northeastern Algeria (Wilaya of Tebessa) based on empirical model using analytic hierarchy process (AHP), fuzzy analytic hierarchy process (FAHP) approaches, and geomatics-based techniques. Sixteen causative factors were used incorporating meteorological, soil erodibility, physical environment, and anthropogenic impacts as main available inputs in this approach. Weighted linear combination (WLC) algorithm was used to combine all standardized raster layers. Area under curve (AUC) value equal 0.96 indicate an excellent accuracy for the proposed approach. Globally, wind erosion risk increase gradually from the north to south of the whole area. Besides, it was found that areas with slight, moderate, high, and very high covered 9.65 %, 25.83 %, 24.30 %., and 40.22 %, respectively of the total. Our results highlighted the potential of additive linear model, and free available medium resolution multi-source remote sensing data in studying natural hazards and disasters mainly under data-scarce or areas of difficult access in developing countries. In addition, restoration and re-vegetation activities of sensitive areas at high risk of wind erosion represent a challenge for researchers and decision-makers.
I Think, Therefore I Forgive: The Role of Reasoning in Forgiving Accidental Harms
Authors: Patil Indrajeet , Trémolière Bastien 
Published: April 2021

Abstract
People experience a strong conflict while evaluating actors who unintentionally harmed someone - her innocent intention exonerating her, while the harmful outcome incriminating her. Different people solve this conflict differently, suggesting the presence of dispositional moderators of the way the conflict is processed. In the present research, we explore how reasoning ability and cognitive style relate to how people choose to resolve this conflict and judge accidental harms. We conducted three studies in which we made vary the reasoning measures and the population. The results showed that individual differences in reasoning ability and cognitive style predicted severity of judgments in fictitious accidental harms scenarios, with better reasoners being less harsh in their judgments. Internal meta-analysis confirmed that this effect was robust only for accidental harms. We discuss the importance of individual differences in reasoning ability in the assessment of accidental harms.
Prognostic Value of Pretreatment Overweight/obesity and Adipose Tissue Distribution in Resectable Gastric Cancer: A Retrospective Cohort Study
Authors: Gu Lihu , Zhang Yangfan , Hong Jiaze , Xu Binbin , Yang Liuqiong , Yan Kun , Zhang Jingfeng , Chen Ping , Zheng Jianjun , Lin Jie 
Published: April 2021

Abstract
Background: This is a study aimed at exploring the relationship between pretreatment overweight/obesity, adipose tissue distribution, and long-term prognosis of gastric cancer.Methods: A total of 607 gastric cancer patients were involved in the retrospective cohort study. Overweight/obese patients was defined as body mass index (BMI) greater than 25 kg/m2 and adipose tissue distribution parameters, including visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), and VAT/SAT ratio were measured at the level of the third lumbar vertebra using computerized tomography images within 15 days before the surgery. Multiple Cox regression models were applied to evaluate the association between overweight/obesity and disease-specific survival (DSS) of gastric cancer and covariates including age, gender, T stage, N stage, and chemotherapy were adjusted. Furthermore, multiple Cox regression models were performed to evaluate the association between adipose tissue distribution parameters and DSS of gastric cancer, expect for covariates mentioned above, overweight/obesity was adjusted additionally.Results: Overweight/obesity was a protective factor (HR = 0.61, 95% CI: 0.37-0.99) for the prognosis of gastric cancer. While high SAT percentage was independently related to a good prognosis, high VAT percentage and high VAT/SAT ratio were independently related to poor prognosis of resectable gastric cancer.Conclusion: These results suggest that overweight/obesity is a protective factor for the prognosis of gastric cancer. The VAT/SAT ratio could be used as a promising prognostic factor for gastric cancer. Therefore, in preoperative evaluation of gastric cancer patients, attention should be paid not only to BMI but also to adipose tissue distribution.
Determinants of Skilled Birth Attendance Utilization Among Mothers Who Gave Birth In The Past 24 Months In Kembata Tembaro Zone
Authors: Mathewos Eyassu , Kassa Belete 
Published: April 2021

Abstract
Background: Skilled delivery is encouraged as a single most important strategy in preventing maternal and neonatal morbidity and mortality. It ensures safe birth, reduce both actual and potential complications and increase the survival of most mothers and newborns. Little is known on current factors that affect utilization of skilled birth attendance in the study area. Therefore this study was aimed identify determinants of skilled birth attendance utilization among women who gave birth in the last 24 months preceding the studyMethods: A community based cross-sectional study was employed among women who gave birth in the last 24 months prior to the survey in Kembata Tembaro zone from April 1 to 30, 2020. 624 study participants were recruited for the study as eligible study participants. Multi-stage stratified sampling was used to select three districts and one town administrative unit of the study area. The data were collected and verified for their completeness, edited, and coded. Multivariate analysis was performed using the back ward LR method to identify factors independently associated with dependent variable. Statistical significance was declared at p-value of less than 0.05 and the strength of statistical association was measured by adjusted odds ratios and 95% confidence intervals.Results: In this study, 375(61.8%) women gave their last birth at health institutions being attended by skilled birth attendants. Place of residence [AOR (95% CI)=0.33(0.215, 0.582)], age at interview [AOR (95% CI=3.41(1.572, 5.449)], maternal education [AOR (95% CI)=1.50(1.336, 4.193)], history of still birth [AOR (95% CI)=3.85(2.144, 6.905)], maternal occupation [AOR (95% CI)=3.35(1.793,6.274)], husband occupation [AOR (95% CI)=2.69(1.701,7.986)], ANC visit [AOR (95% CI) =4.62(3.124, 7.324)], knowledge about obstetric complications [AOR (95% CI) =3.10(1.371,5.214)] and final decision maker about place of delivery [AOR (95% CI)= 3.64(1.701,7.986)] were significant with utilization of skill birth attendance.Conclusion: In this study, about two fifth of the respondents were delivering in the home without using unskilled delivery attendant. Place of residence, age at interview, maternal education, history of still birth, maternal occupation, husband occupation, ANC visit, knowledge about obstetric complications and final decision maker about place of delivery were determinants of utilization of skilled attendant delivery.
Changes of Entropy Connectivity of the Default Mode and Central Executive Networks in ASD
Authors: Zhao Haichen , Lv Rui , Cai Xiaotao , Zhang Guangyu 
Published: April 2021

Abstract
Background: Autism spectrum disorder (ASD) is a heterogeneous disorder characterized by different levels of repetitive and stereotypic behavior as well as cognitive deficit. Brain structural and functional changes of individuals with ASD have been reported in previous investigations. To provide more implications for clinical diagnosis and treatment of ASD, it is necessary to further explore the changes of cerebral neural activities in ASD.Method: We reinvestigate the brain functional networks (viz. the default mode network (DMN) and central executive network (CEN)) of ASD utilizing entropy connectivity (a kind of causal connectivity) method and nodal degree (a topological property in graph theoretical analysis). Eighty-nine patients with ASD and 94 age-matched typical developing (TD) teenagers participated in this study.Result: Two-sample t tests revealed weakened entropy connectivity in the right dorsolateral prefrontal cortex and the left supramarginal gyrus in the CEN, as well as reduced entropy connectivity in the ventral posterior cingulate cortex and the retrosplenial cingulate cortex but enhanced asynchronous output entropy connectivity from the right dorsal frontal cortex to the left piriform cortex in the DMN in patients with ASD. In addition, we also noted significantly decreased nodal degrees in the right somatosensory association cortex and the supramarginal gyrus in individuals with ASD.Limitation: The differences of data from different sites in MRI acquisition settings, such as keep eye open or close, decline the credibility of the results. And further discussion is blocked for BAs template, the lack of ADOS data in ABIDE I and regardless of the effect of sensorimotor related cortex. Conclusion: These findings indicate that overconnecitivity and underconnecitivity in the CEN and DMN might be an important factor that contributes to executive and cognitive disorders of individuals with ASD.
Theoretical Study of The Chemical Reactivity of A Class of Trivalent Phosphorus Derivatives Towards Polyhaloalkanes: DFT Study.
Authors: Barhoumi Ali , idrissi Mohammed El , Zeroual Abdellah , Tounsi Abdessamad , Bakkas Salam , hajbi Abdeslam El 
Published: April 2021

Abstract
In the current work, the chemical reactivity of some trivalent phosphorus derivatives R2PR' towards polyhaloalkanes CCI3POR''2 was studied by the quantum method DFT/B3LYP/6-311G (d,p). The introduction of substituents for the trivalent phosphorus derivative and polyhaloalkane allowed us to have more information on these reactions. On the one hand, the calculation of reactivity indices derived from the DFT/B3LYP/6-311G(d,p) method and the gapLUMO-HOMO show that trivalent organophosphorus derivatives behave as nucleophiles, while polyhaloalkanes act as electrophiles. On the other hand, the calculation of the activation barrier and the determination of the free enthalpy variation prove that the kinetic and thermodynamic products of these reactions result from the nucleophilic attack of the phosphorus atom on the chlorine halogen. All these theoretical predictions are in very good agreement with the experimental results.
Difference in Risk Factors Associated with Acute Respiratory Distress Syndrome and Intubation/Death in Patients with Coronavirus Disease 2019: A Two-hospital Retrospective Cohort Study in Hubei, China
Authors: Mu Jing-Lan , Qin Ming-Zhe , Sun Hui-Mei , Guo Bao-Sheng , Qiu Shi-Da , Zhang Fu , Yang Huang , Nie Juan , Liu Xu-Dong , Yeung Wing-Fai , Liu Xiao-Dong , Dong Ye-Hong , Li Bi-Xi , Song Xiao-Yang , Lin Shao-Yan , Liu Ke-Xuan 
Published: April 2021

Abstract
Background: The reviews on the risk factors with ARDS and the worse outcomes concluded lacking robust data of risk factors to prevent COVID-19 and identified an urgent need for large sample and high-quality research in this area, as well as the features of the ARDS.Methods: This retrospective cohort study included 333 COVID-19 inpatients at two hospitals in Hubei of China in 2020. The COVID-19-related ARDS was diagnosed according to the Berlin criteria. The outcomes were ARDS development and the intubation or in-hospital death. The cox proportional hazard ratio (HR) models were employed to determine the significant risk factors. Results: The median number of days from symptom onset to ARDS diagnosis was 11.0 (IQR, 8.0–13.0). Up to 84.1% COVID-19-related ARDS patients demonstrated multiple organ injuries. The mortality rates were 41.9% and 85.7% in moderate and severe ARDS. The survival patients on invasive mechanical ventilation (IMV) had been intubated earlier since ARDS diagnosis than those who had not survived (5.5 median days, IQR 4.0-7.0 days versus 11.5 median days, IQR 6.0-14.0 days, P < 0.001). Males and all abnormal laboratory indices associated with the higher risk of ARDS (P<0.05) but were not linked with the risk of intubation or death (P>0.05). The sensitivity analyses found that lymphocyte count of < 1000 per mm3 at hospital admission were still significantly associated with developing ARDS when adjusting for age and male gender (HR, 4.10; 95% CI, 2.40-7.10), and oxygenation index (OI) ratio < 150 were more likely to predict the intubation/death after age adjustment (HR, 2.50; 95% CI, 1.17-5.30). Conclusion: The SARS-CoV-2-caused ARDS was not the typical ARDS according to Berlin criteria. The alive patients with IMV had been intubated earlier since ARDS diagnosis than those who had not survived. We identified male gender and abnormal laboratory indices associated with the ARDS but were not linked with the intubation/death. Sensitivity analysis concluded lymphocyte count of < 1000 per mm3 could predict ARDS while OI ratio less than 150 could predict intubation/death.
Dynamic Behavior of T-beam Resonator With Repulsive Actuation
Authors: Tian Yu , Daeichin Meysam , Towfighian Shahrzad 
Published: April 2021

Abstract
We introduce a MEMS resonator that uses a "T"-shape beam driven by repulsive force, of which the first advantage is to avoid pull-in instability; thus, high enough voltages can be applied to the MEMS system to tune the center frequency. A T-beam model is derived from the beam-paddle hypothesis, and theoretical analysis regarding both static and dynamic behaviors, including primary resonance and secondary resonance, is conducted. This study shows an electrostatic T-beam resonator's feasibility based on repulsive force and outlines its advantages over a traditional cantilever beam resonator. Additional micro-paddle to the micro-beam means larger surface for absorption of targeted analytes and lower natural frequency, but higher resonant responses. We present a thorough analysis of primary and parametric resonances, which can enhance the system signal-to noise ratio and response time. This design enables potential applications in MEMS mass-sensors, where a large area for attachment and a high resolution are often vital.