bluuebunny/crossref_metadata_2025_split huggingface dataset:
Occupational, health and safety situation at small and medium enterprises in Kosovo, contextual factors, barriers, drivers and intervention process
Authors: Dugolli Mimoza 
Published: February 2021

AbstractThis survey has been performed as part of a wider survey within the Western Balkan Small and Medium Sized Enterprises (SME) Competitiveness Support Project. It presents the current situation of occupational health and safety (OHS) management at 18 SMEs in Kosovo. SMEs in the Republic of Kosovo are facing many difficulties in identifying the real need for interventions, recruiting adequate professional staff to support their activities in OHS. Exposed to an opened market under the regional and international competition, their sustainability has become more difficult and their financial fragility leads very often to the ignorance of OHS issues within their organization.The first objective of this research aimed to understand the OHS contextual factors, barriers and drivers based on the current practice of SMEs in Kosovo. The second objective was to find out if the OHS “ideal intervention process” is applicable to achieve improvements for SMEs in Kosovo. Data collection was expedited through internal documents review, site visits and questionnaires. The statistical data were subject to descriptive analyses and inferential statistics. The findings showed that the contextual factors which influence the intervention process, were of participatory nature, cognitive and physical workplace environment, while the perceived barriers were mainly coming from lack of resources and information. Finally the features of OHS “ideal intervention process” were analyzed and compared for applicability to the SMEs in Kosovo and several interventions in this regards were proposed.
Enhanced neural responses in specific phases of reward processing in individuals with Internet gaming disorder
Authors: Wang Lingxiao , Yang Guochun , Zheng Ya , Li Zhenghan , Qi Yue , Li Qi , Liu Xun 
Published: February 2021

AbstractBackground and aimsInternet gaming disorder (IGD) has become a global health problem. The self-regulation model noted that a shift to reward system, whether due to overwhelming reward-seeking or impaired control, can lead to self-regulation failures, e.g., addiction. The present study focused on the reward processing of IGD, aiming to provide insights into the etiology of IGD. Reward processing includes three phases: reward anticipation, outcome monitoring and choice evaluation. However, it is not clear which phases of reward processing are different between individuals with IGD and healthy controls (HC).MethodsTo address this issue, the present study asked 27 individuals with IGD and 26 HC to complete a roulette task during a functional MRI scan.ResultsCompared with HC, individuals with IGD preferred to take risks in pursuit of high rewards behaviorally and showed exaggerated brain activity in the striatum (nucleus accumbens and caudate) during the reward anticipation and outcome monitoring but not during the choice evaluation.DiscussionThese results reveal that the oversensitivity of the reward system to potential and positive rewards in college students with IGD drives them to approach risky options more frequently although they are able to assess the risk values of options and the correctness of decisions properly as HC do.ConclusionsThese findings provide partial support for the application of the self-regulation model to the IGD population. Moreover, this study enriches this model from the perspective of three phases of reward processing and provides specific targets for future research regarding effective treatment of IGD.
Problematic internet-related behaviors mediate the associations between levels of internet engagement and distress among schoolchildren during COVID-19 lockdown: A longitudinal structural equation modeling study
Authors: Chen I-Hua , Chen Chao-Ying , Pakpour Amir H. , Griffiths Mark D. , Lin Chung-Ying , Li Xu-Dong , Tsang Hector W. H. 
Published: February 2021

AbstractBackground and aimsDue to the rapid spread of the novel coronavirus disease 2019 (COVID-19), policies based on the nature of “spatial distancing” have been implemented and have resulted in school suspensions and online learning among schoolchildren. In order to examine the impact of such policies on schoolchildren, the aims of the present study were to (i) assess changes in the level of engagement in three internet-related activities (smartphone use, social media use, and gaming) before and during the COVID-19 outbreak, including prolonged and problematic engagement in these activities; (ii) investigate the differences of psychological distress before and after COVID-19 outbreak; and (iii) to use structural equation modeling to investigate the mediating roles of problematic internet-related behaviors in the causal relationships of psychological distress and time spent on internet-related activities.MethodsSelf-report measures were used to assess internet-related activities and psychological distress. Time spent on internet-related activities, problematic use of internet-related activities, and psychological distress were collected from primary school students (N = 535; 265 boys; M age = 10.32 years [SD = 0.84]). The data were first collected before the COVID-19 outbreak (i.e., early November 2019) and then collected again during the school suspension due to COVID-19 outbreak (i.e., end of March 2020) for comparisons of changes.ResultsSchoolchildren spent significantly more time on the smartphone (increased 1.02 h daily; P < 0.001) and social media (increased 0.73 h daily; P < 0.001) but not gaming (increased 0.14 h daily; P = 0.07) during the school suspension compared to the baseline. Schoolchildren who increased by 15 or 30 min daily on internet-related activities showed an increased level of psychological distress. The association between problematic use of social media and psychological distress was stronger during the school suspension (β = 0.584) than at the baseline (β = 0.451; P < 0.001).ConclusionIncreased problematic use of internet-related activities among schoolchildren was associated with greater psychological distress. Parents should therefore monitor internet-related activities and psychological distress of their children to support their mental health.
Circ-RNF13, as an oncogene, regulates malignant progression of HBV-associated hepatocellular carcinoma cells and HBV expression and replication through circ-RNF13/miR-424-5p/TGIF2 ceRNA pathway
Authors: Chen Yan , Li Shuhua , Wei Yinbin , Xu Zhihong , Wu Xiongfei 
Published: February 2021

The circular RNA RNF13 (circ-RNF13; ID: hsa_circ_0067717) is a novel identified abnormally upregulated circRNA in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) patients. However, its role and mechanism remain to be further annotated. The expression of circ-RNF13, microRNA (miR)-424-5p, and TGFβ-induced factor homeobox 2 (TGIF2) were detected by real-time quantitative PCR and western blotting, and their interaction was confirmed by dual-luciferase reporter assay. Functional assays were performed using MTS assay, colony formation assay, flow cytometry, enzyme-linked immunosorbent assay, transwell assay, and xenograft tumor model, along with real-time quantitative PCR. Circ-RNF13 was upregulated in HBV-infected human HCC tissues and HBV-expressing cells (Huh7-HBV and Hep3B-HBV), accompanied with TGIF2 upregulation and miR-424-5p downregulation. Blocking circ-RNF13 enhanced the apoptosis rate of Huh7-HBV and Hep3B-HBV cells but inhibited cell viability, colony formation, migration, and invasion, along with suppressed tumor growth in vivo. Besides, HBV DNA copies and levels of hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) were diminished by circ-RNF13 knockdown in Huh7-HBV and Hep3B-HBV cells. Mechanistically, circ-RNF13 and TGIF2 served as competing endogenous RNAs (ceRNAs) for miR-424-5p. Overexpressing miR-424-5p mimicked and silencing miR-424-5p counteracted the effects of circ-RNF13 depletion in HBV-expressing HCC cells in vitro. Consistently, TGIF2 restoration partially abrogated the role of miR-424-5p upregulation in Huh7-HBV and Hep3B-HBV cells. The circ-RNF13 sponged miR-424-5p to suppress HBV-associated HCC cells malignant progression and HBV infection by regulating TGIF2, providing a novel insight into the occurrence and treatment of HBV-associated HCC.
Internal or External Financing: New Evidence on Investor Reaction in Indonesian Manufacturing Firms
Authors: Fikasari Rifki , Bernawati Yustrida 
Published: February 2021

Research aims: This study aims to examine investor reaction to financing sources due to its pecking order theory hierarchy.Design/Methodology/Approach: This research used a purposive sampling method of manufacturing listed firms on the Indonesia Stock Exchange, which were tested utilizing Ordinary Least Square and SPSS software.Research findings: The results showed that the investor reacted negatively to internal financing measured by the firm's retained earnings. Conversely, this research found that investors reacted positively to external financing in measurement, leverage, and equity issuance. Furthermore, the results revealed that leverage had a more positive reaction than equity issuance.Theoretical contribution/Originality: This research contributes to the pecking order theory literature to test how investor reacts to which source of financing is chosen due to its hierarchy. There is evidence that Indonesian manufacturing firms had inadequate internal financing, which made investors react negatively, and investors tended to choose leverage over equity as external financing.Practitioner/Policy implication: Our study contributes to the firm's management to carefully choose financing sources to fulfill the investor interest. This research also suggests that the firm produces more profit to provide adequate internal source financing as the research results showed that investors preferred internal than external financing. Furthermore, when there is inadequate internal financing, the firm's management should use leverage over equity.Research limitation/Implication: First, our study employed total liability rather than debt to leverage measurement. Second, our study only provided evidence of negative reactions to show that the firm failed to provide adequate internal financing sources rather than examined the level of adequate internal financing sources.
Spectrum of uncommon malignancies in pleural fluid cytology: A study from a tertiary care center in South India
Authors: Sadasivan Baalu , Dharmalingam Priya , Mukundapai Malathi , Nargund Ashwini , Alashetty Soumya 
Published: February 2021

Pleural fluid cytology is a useful diagnostic test to detect metastasis to pleura. Among the metastatic neoplasms to pleural cavity adenocarcinoma is the most common. However there are other neoplasms which rarely infiltrate pleura and produce effusion. The aim of this study is to analyse the spectrum of these unusual malignancies involving pleural fluid with cytomorphology and ancillary studies.This is a retrospective study which includes the pleural fluid samples submitted to the cytology section of our institute between 2015 to 2018. A total of 1510 samples are reviewed. Cases with diagnosis other than adenocarcinoma are selected and their cytomorphological details are analysed with ancillary tests wherever available. Out of 1510 samples analysed, 468 are positive for malignancy. Out of 468, 42 cases are uncommon malignancies. These are classified into hematolymphoid (33/42 cases) which includes Nonhodgkin lyphoma, acute lymphoblastic leukemia, chronic myeloid leukemia, multiple myeloma and nonhematolymphoid neoplasms (9 /42) which includes small round cell tumours, squamous cell carcinoma, small cell carcinoma, germ cell tumor and granulosa cell tumour. There are certain uncommonly encountered malignancies in pleural fluid. Cytomorphology plays a key role in diagnosing them with certain cases requiring ancillary studies to confirm the diagnosis.
Real time ultrasound guided fine needle aspiration cytology of intra-abdominal and intra-pelvic masses- synergistic approach of radiologist and cytopathologist for better cellular yield
Authors: Sinha Sweta , Prabhakar Rao Vatturi Venkat Satya , Bhuvan L P Bhaskar , R E A Muthu , Bora Muralidhar 
Published: February 2021

Real time ultrasound guided fine needle aspiration cytology (FNAC) of non-palpable, intra-abdominal and intra-pelvic masses are easily performed and reported rapidly. Needle tip can be visualized and manipulated on real time aspirations. It increases the sensitivity due to high diagnostic yield from target areas. The present study is a retrospective study of 161cases, where real time ultrasound guided FNAC of intra-abdominal and intra-pelvic masses were done from 1 July 2018 to 31 December 2019 in a tertiary cancer center. Aspirations from ovary and other pelvic masses-18 gauge, liver/gall bladder-22- 23 gauge and kidney-23 gauge spinal needles were taken respectively. Total 161 cases of intra-abdominal lesions- ovary- 73 cases, liver-45 cases, kidney-27 cases, gall bladder-07 cases, colon (caecum+descending colon)-03 cases and pelvis mass- 03cases, pancreas- 02 cases and retroperitoneal lymph node-01 case were retrieved and studied. Ultrasound guided aspirates were conclusive for reporting in 145 cases, inconclusive for reporting in 10 cases and acellular/ haemorrhagic in 06 cases. There was high sensitivity and specificity of 90.9% and 100% respectively. Real time image guided FNAC is the method of choice for intra-abdominal masses with better cell yield and minimal complication. It permits precise localization and targeting of lesions safely. The localization is good in most of the masses but, it’s challenging in few locations. Complication like needle track seedling, discussed in many studies, was not seen in the present study.Image guided FNAC is very rewarding in diagnosis of intra-abdominal masses. USG guided FNAC is easy, causes minimal radiation, rapid reporting, less complication and needle tip can be easily visualized and manipulated in any direction, thus aids in faster planning if the treatment.
KINERJA TEORITIS, KINERJA AKTUAL DAN EFESENSI MESIN HUMMER MILL PADA PENGGILINGAN TONGKOL JAGUNG
Authors: Latief Muhammad Fadhlirrahman , Syamsu Jasmal A , Jamila . , Jamilah Jamilah 
Published: February 2021

Hammer mill merupakan teknologi penggilingan bahan pakan yang bekerja dengan prinsip tumbukan. Kinerja mesin mempengaruhi dari efesiensi penggilingan. Penelitian ini bertujuan untuk mengetahui kinerja teoritis (KT), Kinerja Aktual (KA), dan efesiensi mesin hammer mill pada penggilingan tongkol jagung. Penelitian menggunakan rancangan acak lengkap (RAL) dengan 4 perlakuan dan 3 ulangan sebagai berikut P1 (berat tongkol jagung 1 kg), P2 (berat tongkol jagung 2 kg, P3 (berat tongkol jagung 3 kg), dan P4 (berat tongkol jagung 4 kg). Total unit perlakuan yaitu 12 unit percobaan. Parameter yang diukur yaitu KT (kg/menit), KA (kg/menit), efesiensi mesin (%). Hasil penelitian menunjukkan bahwa P4 memiliki perbedaan yang nyata (P<0,05) dengan nilai KA 0,82 ± 0,07 kg/menit dan 76 ± 0,08 kg/menit. P2 paling efesien dalam proses penggilingan dengan nilai efesiensi 99%.Kata kunci: efesiensi, hammer mill, kinerja mesin, tongkol jagung.
Application of Computational Intelligence in Generating Synthetic Reservoir Rock Mechanical Parameters for Building Geo-Models.
Authors: Akubue L. C. , Dosunmu A. , Beka F. T. 
Published: February 2021

Abstract
Oil field Operations such as wellbore stability Management and variety of other activities in the upstream petroleum industry require geo-mechanical models for their analysis. Sometimes, the required subsurface measurements used to estimate rock parameters for building such models are unavailable. On this premise, past studies have offered variety of methods and investigative techniques such as empirical correlations, statistical analysis and numerical models to generate these data from available information. However, the complexity of the relationships that exists between the natural occurring variables make the aforementioned techniques limited. This work involves the application of Artificial Neural Networks (ANNs) to generating rock properties. A three-layer back-propagation neural network model was applied predicting pseudo-sonic data using conventional wireline log data as input. Four well data from a Niger-Delta field were used in this study, one for training, one for validating and the two others for generating and testing results. The network was trained with different sets of initial random weights and biases using various learning algorithms. Root mean square error (RMSE) and correlation coefficient (CC) were used as key performance indicators. This Neural-Network-Generated-Sonic-log was compared with those generated with existing correlations and statistical analysis. The results showed that the most influential input vectors with various configurations for predicting sonic log were Depth-Resistivity-Gamma ray-Density (with correlating coefficient between 0.7 and 0.9). The generated sonic was subsequently used to compute for other elastic properties needed to build mechanical earth model for evaluating the strength properties of drilled formations, hence optimise drilling performance. The models are useful in Minimizing well cost, as well as reducing Non Productive Time (NPT) caused by wellbore instability. This technique is particularly useful for mature fields, especially in situations where obtaining this well logs are usually not practicable.
Sequence Stratigraphic, Structural and Reservoir Analyses: An Integrated Approach to Exploration and Development of the Eastern Coastal Swamp Cluster, Niger Delta Basin
Authors: Dim C. I. , Onuoha K. Mosto , Okeugo C. Gabriel 
Published: February 2021

ABSTRACT
Sequence stratigraphic, structural and reservoir analytical tools have been employed in interpreting the geology of the eastern Coastal Swamp Depo-belt of the Niger Delta Basin. The aim was to understand the stratigraphic framework, structural styles and hydrocarbon reservoir distribution for improved regional hydrocarbon exploration across the onshore Niger Delta basin. This interpretative study made use of well logs, biostratigraphic (biofacies and bio-zonation) and petrophysical data obtained from twenty wellbores, integrated with recently merged and reprocessed 3D Pre-Stack Time Migrated regional seismic volume spanning across eight fields (over 960 km2). Results reveal the occurrence of nine key chronostratigraphic surfaces (five maximum flooding surfaces and four sequence boundaries) that were tied to well-established pollen and foram bio-zones for high resolution sequence stratigraphic interpretation. The sediment stacking patterns recognized from gamma ray log signatures were used in delineating the lowstand system tract (LST), transgressive system tract (TST) and highstand system tract (HST) genetic units. Well log sequence stratigraphic correlation reveals that stratal packages within the area were segmented into three depositional sequences occurring from middle to late Miocene age. Furthermore, there is thickening of stratal packages with corresponding decrease in net-to-gross thickness from north to south (basinwards). This is due possibly to the influence of syn-depositional structures on stratigraphy. The combination of reservoir sands (of LST and HST), source and seal shales (of TST and HST) and fault structures allows for good hydrocarbon accumulation and should be targeted during exploration. Reservoir evaluation studies using petrophysical parameters indicates the presence of good quality reservoir intervals, which are laterally continuous and partly compartmentalized. Structural top maps of reservoirs show good amplitude response that are stratigraphically and structurally controlled. Structural analysis revealed the occurrence of back-to-back faulting, collapsed crest structures, simple/faulted rollovers, regional foot wall and hanging wall closures and sub-detachment structures. These structural styles constitute the major hydrocarbon entrapment mechanism in the area. Overall, the study has unraveled the existence of undrilled hydrocarbon leads at deeper depths that should be further revalidated for development and production.
Production Optimization in a Marginal Field through Established Reservoir Management Techniques – A Case Study
Authors: Toluse Williams , Okolo Victor , Martey Amarquaye 
Published: February 2021

ABSTRACT
The Federal Government of Nigeria in a bid to promote indigenous companies participation in the oil and gas sector, and to grow the nation&rsquo;s production capacity passed legislation in 1999 to foster the exploitation of Marginal Oil Fields (MOFs). MOF is one that is considered non &ndash; commercial as a result of strategic business development philosophy of the operator, often times large oil companies. Reservoir management is central to the effective exploitation of any hydrocarbon asset; this dependence is heightened for an undeveloped marginal field. There is no &lsquo;one-size fits all&rsquo; approach to reservoir management; this paper reviews some techniques adopted by Midwestern Oil and Gas Ltd in the development of the Umusadege marginal field.
These techniques fall under three categories: (I) subsurface study (II) well placement and spacing, (III) integrated surface production and optimization, in accordance with regulatory practices.
The previously acquired 3-D seismic data was reprocessed and interpretation of reservoir heterogeneities within the Umusadege field concessionary boundary carried out form the basis of the initial field development plan. To optimize reservoir drainage, the general principles of non-interference well spacing were employed, and advanced well placement technology was deployed to guarantee optimum well placement within the reservoir for effective and efficient drainage.
Subsequently, 14 vertical wells and 4 horizontal wells were drilled to effectively optimize recovery from the field. Prior to bringing these wells on-stream, clean-up and Maximum Efficiency Rate (MER) tests were conducted to determine the optimum choke settings, GOR and water cut limits for all wells. An integrated approach encompassing choke sizing, gas and water production management, vessel and line sizing were implemented on the Umusadege field to maintain and optimize recovery. Crude custody transfer measurements and export were enabled by an optimized Group Gathering Facility (GGF).The above techniques combining new technologies, traditional reservoir and production strategies led to the successful development of the Umusadege field; increasing daily oil production from 2,000 bbls/d from the first well re-entry to approximately 30,000 bbls/day over a 7-year period. This case study proves that with the correct implementation of the key elements of reservoir management the value of any hydrocarbon asset can be maximized in a cost effective, safe and environmentally friendly manner.