bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing the Performance of Knee Beam–Column Joint Using Hybrid Fibers Reinforced Concrete
Authors: Zainal S. M. Iqbal S. , Hejazi Farzad , Rashid Raizal S. M. 
Published: April 2021

AbstractThe knee beam–column joint is a critical location in a Reinforced Concrete (RC) structure particularly when subjected to earthquake vibrations. The current structural design codes dictate the use of high amounts of steel reinforcements in the frame joint to manage large strain demands in seismic-prone regions. However, these codes could result in the congestion of steel reinforcements in the limited joint area which can consequently produce numerous construction complications. This study aims to improve the structural performance of Knee Joint (KJ) by reducing the load induced to the embedded steel reinforcements during seismic vibrations. Hence, this study attempted to develop a Hybrid Fiber Reinforced Concrete (HyFRC) by combining multiple synthetic fibers to be introduced onto KJ. Six KJ specimens were cast using five developed HyFRC materials and one Control specimen to be experimentally tested under lateral cyclic loading. The results indicated significant improvements for the HyFRC KJ specimens particularly in energy dissipation capacity, stiffness degradation rate, displacement ductility toughness, steel reinforcement strain and hysteretic behavior. A total of six Finite Element (FE) KJ models were developed using the HyFRC materials to verify the results from the experimental testing. The accuracy of the proposed FE models resulted in average percentage differences of 25.89% for peak load, 3.45% for peak load displacement and 0.18% for maximum displacements from the experimental data. In conclusion, this study developed HyFRC materials that are beneficial in providing cost-efficient alternatives to Reinforced Concrete (RC) KJ structures in areas with low to moderate level of seismic risks.
Cross-cultural adaptation of motivational interviewing for use in rural Nepal
Authors: Rimal Pragya , Khadka Sonu , Bogati Bhawana , Chaudhury Jamuna , Rawat Laxmi Kumari , Bhat Kumari Chhaya , Manandhar Pramita , Citrin David , Maru Duncan , Ekstrand Maria L. , Swar Sikhar Bahadur , Aryal Anu , Kohrt Brandon , Shrestha Srijana , Acharya Bibhav 
Published: April 2021

Abstract
Background
Motivational Interviewing (MI) has a robust evidence base in facilitating behavior change for several health conditions. MI focuses on the individual and assumes patient autonomy. Cross-cultural adaptation can face several challenges in settings where individualism and autonomy may not be as prominent. Sociocultural factors such as gender, class, caste hinder individual decision-making. Key informant perspectives are an essential aspect of cross-cultural adaptation of new interventions. Here, we share our experience of translating and adapting MI concepts to the local language and culture in rural Nepal, where families and communities play a central role in influencing a person’s behaviors.

Methods
We developed, translated, field-tested, and adapted a Nepali MI training module with key informants to generate insights on adapting MI for the first time in this cultural setting. Key informants were five Nepali nurses who supervise community health workers. We used structured observation notes to describe challenges and experiences in cross-cultural adaptation. We conducted this study as part of a larger study on using MI to improve adherence to HIV treatment.

Results
Participants viewed MI as an effective intervention with the potential to assist patients poorly engaged in care. Regarding patient autonomy, they initially shared examples of family members unsuccessfully dictating patient behavior change. These discussions led to consensus that every time the family members restrict patient's autonomy, the patient complies temporarily but then resumes their unhealthy behavior. In addition, participants highlighted that even when a patient is motivated to change (e.g., return for follow-up), their family members may not “allow” it. Discussion led to suggestions that health workers may need to conduct MI separately with patients and family members to understand everyone’s motivations and align those with the patient’s needs.

Conclusions
MI carries several cultural assumptions, particularly around individual freedom and autonomy. MI adaptation thus faces challenges in cultures where such assumptions may not hold. However, cross-cultural adaptation with key informant perspectives can lead to creative strategies that recognize both the patient’s autonomy and their role as a member of a complex social fabric to facilitate behavior change.
Linking market authorizations of medicines with disease burden in South Africa
Authors: Narsai K. , Leufkens H. G. M. , Mantel-Teeuwisse A. K. 
Published: April 2021

Abstract
Background
Sub-Saharan Africa is going through an epidemiological transition, including an impressive increase in non-communicable diseases. The introduction of medicines has not kept pace with the needs in developing countries. The objectives of this study were to (i) examine the correlation between the number of medicine approvals and disease burden and (ii) compare approval timelines of medicines with disease burden in South Africa in the period 2012–2017.

Methods
The dataset was compiled from publicly available data on medicines registered in South Africa between 2012 and 2017. A correlation analysis was conducted to determine the level of alignment between the number and nature of medicines registered, as determined by the WHO ATC Classification and the Lancet Global Burden of Disease data. Median registration timelines were determined to assess whether medicines for diseases of higher burden were registered faster.

Results
A total of 3059 registered medicines were included in the study, including 2779 generic medicines, 267 new chemical entities and 13 vaccines. There was a high level of alignment between the number of medicines registered to treat diseases with higher disease burden levels more effectively, except for lower respiratory tract infections and HIV/AIDS which showed less medicines registered as compared to expectations based on disease burden, respectively. HIV/AIDS showed a lower level of correlation with a much higher disease burden compared to number of medicines registered, but simultaneously also a much shorter median registration timeline (32 months) compared to the other disease areas.

Conclusions
There was generally a high level of alignment between disease burden and number of medicines authorised, except for HIV/AIDS and lower respiratory tract infections. Regulatory authorities should continue to consider burden of disease data to ensure that public health needs are met.
Bistatic scattering simulations of circular and linear polarizations over land surface for signals of opportunity reflectometry
Authors: Wu Xuerui , Song Yezhi , Xu Jin , Duan Zheng , Jin Shuanggen 
Published: April 2021

AbstractSignals of Opportunity Reflectometry (SoOp-R) employs the communication system, GNSS (Global Navigation Satellite System) constellation and other potential Signals of Opportunity (SoOp) as the transmitters. In recent years, it has gained increased interests. Several experiments have been carried out, however it is still in the initial development stage. Theoretical predictions of SoOp Reflectometry for land surface parameters detection, such as soil moisture and vegetation biomass, should be carried out simultaneously. Meanwhile, at present less works are paid attention to the polarization study of the polarizations. The first-order radiative transfer equation models are employed here and they are developed according to the wave synthesis technique to get the various polarization combinations. Using the two models as analysis tools, we simulate the bistatic scattering at all potential SoOp Reflectometry bands, i.e., P-, L-, C- and X-band for circular polarizations and linear polarizations. While the original commonly used microwave scattering models are linear polarizations, here we compare the difference. Although the models can simulate bistatic scattering at any incident angles and scattering angles. Four special observation geometry are taken into considerations during the analysis. Using the developed models as tools, the developed models establish the relationship between the land surface parameters (such as soil moisture, soil roughness and vegetation water content, diameters et al.) and bistatic radar cross section. The forward scattering models developed here enables the understanding of the effects of different geophysical parameters and transmitter–receiver observation scenarios on the bisatic scattering at any polarization combinations for any potential SoOP reflectometry bands. Robust retrieval methods for soil moisture and vegetation biomass can benefit from the forward scattering models.
Team-based instructional change in undergraduate STEM: characterizing effective faculty collaboration
Authors: Sachmpazidi Diana , Olmstead Alice , Thompson Amreen Nasim , Henderson Charles , Beach Andrea 
Published: April 2021

Abstract
Background
Team-based instructional change is a promising model for improving undergraduate STEM instruction. Teams are more likely to produce sustainable, innovative, and high-quality outcomes than individuals working alone. However, teams also tend to involve higher risks of failure and can result in inefficient allocation of valuable resources. At this point, there is limited knowledge of how teams in the context of STEM higher education should work to achieve desirable outcomes.

Results
In this study, we collect semi-structured interview data from 23 team members from a total of 4 teams at 3 institutions across the USA. We analyze the results using a grounded theory approach and connect them to the existing literature. This study builds upon the first part of our work that developed a model of team inputs that lead to team outcomes. In this part, we identify the mechanisms by which input characteristics influence teamwork and outcomes. Team member data expand this initial model by identifying key aspects of team processes and emergent states. In this paper, we present five team processes: strategic leadership, egalitarian power dynamics, team member commitment, effective communication, and clear decision-making processes, that shape how teams work together, and three emergent states: shared vision, psychological safety, and team cohesion, that team members perceived as important aspects of how teams feel and think when working together.

Conclusions
This work furthers our understanding of how instructional change teams can be successful. However, due to the highly complex nature of teams, further investigation with more teams is required to test and enrich the emerging theory.
Evaluation of automated microvascular flow analysis software AVA 4: a validation study
Authors: Guay Christian S. , Khebir Mariam , Shiva Shahiri T. , Szilagyi Ariana , Cole Erin Elizabeth , Simoneau Gabrielle , Badawy Mohamed 
Published: April 2021

Abstract
Background
Real-time automated analysis of videos of the microvasculature is an essential step in the development of research protocols and clinical algorithms that incorporate point-of-care microvascular analysis. In response to the call for validation studies of available automated analysis software by the European Society of Intensive Care Medicine, and building on a previous validation study in sheep, we report the first human validation study of AVA 4.

Methods
Two retrospective perioperative datasets of human microcirculation videos (P1 and P2) and one prospective healthy volunteer dataset (V1) were used in this validation study. Video quality was assessed using the modified Microcirculation Image Quality Selection (MIQS) score. Videos were initially analyzed with (1) AVA software 3.2 by two experienced investigators using the gold standard semi-automated method, followed by an analysis with (2) AVA automated software 4.1. Microvascular variables measured were perfused vessel density (PVD), total vessel density (TVD), and proportion of perfused vessels (PPV). Bland–Altman analysis and intraclass correlation coefficients (ICC) were used to measure agreement between the two methods. Each method’s ability to discriminate between microcirculatory states before and after induction of general anesthesia was assessed using paired t-tests.

Results
Fifty-two videos from P1, 128 videos from P2 and 26 videos from V1 met inclusion criteria for analysis. Correlational analysis and Bland–Altman analysis revealed poor agreement and no correlation between AVA 4.1 and AVA 3.2. Following the induction of general anesthesia, TVD and PVD measured using AVA 3.2 increased significantly for P1 (p < 0.05) and P2 (p < 0.05). However, these changes could not be replicated with the data generated by AVA 4.1.

Conclusions
AVA 4.1 is not a suitable tool for research or clinical purposes at this time. Future validation studies of automated microvascular flow analysis software should aim to measure the new software’s agreement with the gold standard, its ability to discriminate between clinical states and the quality thresholds at which its performance becomes unacceptable.
Comparative performance analysis of hybrid differential evolution and pattern search technique for frequency control of the electric power system
Authors: Pradhan Pratap Chandra , Sahu Rabindra Kumar , Panda Sidhartha 
Published: April 2021

AbstractIn the current situation, operation and control of power system is a greater challenge. The most significant situation in power system control is load frequency control. In the present work, a hybrid differential evolution and pattern search (hDE-PS) method has been suggested for frequency regulation of electrical power systems. Fractional-order proportional integral derivative (FOPID) controller is implemented for design and analysis purpose. The suggested control method has been applied for two electrical power systems model, i.e., 2-area diverse source power system with/without HVDC linkage and 2-area thermal system. The performances of the suggested controller have been evaluated with PID and optimal controller. The simulation results indicate that system performances are enhanced with the suggested approach for identical structure. Robustness of the suggested approach has been analyzed by variation in random load and the system parameters. The suggested method (hDE-PS tuned FOPID) is further investigated with a 2-area thermal system. The performance of the recommended approach is analyzed by equating the results with other newly available approaches, like Genetic Algorithm (GA), Bacteria Foraging Optimization Algorithm (BFOA), Particle Swarm Optimization (PSO), hybrid BFOA and PSO (hBFOA-PSO), multi-objective Non-dominated Sorting Genetic Algorithm (NSGA)-II and Firefly Algorithm for the similar structure.
The effect of age at time of cochlear implantation on the pragmatic development of the prelingual hearing impaired children
Authors: Khodeir Mona Sameeh , Moussa Dina Fouad El Sayed , Shoeib Rasha Mohammed 
Published: April 2021

Abstract
Background
Pragmatics is the social use of language that draws on understanding human interactions in specific contexts and requires engagement with a communicative partner or partners. The hearing-impaired children are known to have a pragmatic language delay as hearing impairment deprived of exposure to natural communication interactions, in addition to the language delay they have. Since the age of implantation has emerged as an important predictor of language, hearing, and speech in children who use cochlear implants (CI), question aroused about the benefits of early cochlear implantation on pragmatic language development in those children. Thus, this study aims to compare the pragmatic language development of the prelingual hearing impaired children who cochlear implanted before the age of 3 years and those who cochlear implanted after the age of 3 years.

Results
The two study groups showed no significant differences regard their scores in the Egyptian Arabic Pragmatic Language Test (EAPLT). The two studied groups had pragmatic language scores below their 5th percentile. Among the studied groups, the scores of the EAPLT were positively correlated to the age of the children, the children’s language abilities, and the duration of the received language rehabilitation, with no significant correlation to the age of implantation.

Conclusions
The age of implantation has no impact on pragmatic language development in children with CI. The prelingual children with CI are susceptible to delays in the pragmatic language development that is primarily related to the age of those children and their language abilities, besides their experience in social interactions. These results should be considered in their rehabilitative plan and advocate the importance of early incorporation of pragmatic behaviors into their intervention programs.
Remote Home Monitoring of Patients With Cancer During the COVID Pandemic: A Pilot Study
Authors: Steimer Mary , Leabo Jessica , Wang Hongkun , Heyer David , Addison Nancy , Bowles Nancy , Cannon Timothy L. , Cuevo Raymund , Ershler William B. , Shafer Danielle , Jang Sekwon , Pennisi Angela , Al-Hussain Amjaad , Farrell Kirby , Deeken John F. 
Published: April 2021

PURPOSE:The COVID-19 pandemic has posed significant challenges in the care of patients with cancer, including how to manage outpatients who are COVID-positive but do not require hospitalization. We explored the use of a remote patient monitoring (RPM) program to care for such outpatients.METHODS:Consecutive patients who were tested for COVID-19 because of symptom onset but were clinically stable were offered enrollment into a pilot RPM program. Patients were provided equipment for vital sign measurements and a computer tablet to enter results three times per day. The results were monitored centrally by clinical staff. The goal was to closely monitor patients and escalate care as warranted.RESULTS:Between March and June of 2020, 29 patients were approached and 26 were enrolled. The mean age was 57 years old (range, 30-88), 14 were women, and patients remained in the program for an average of 16 days (range, 2-63). Twenty-four patients (83%) were on active anticancer therapy. During that time period, only one patient was admitted to the hospital for worsening respiratory symptoms. The percentage of days during which at least one set of data and all three sets of data were entered was 97.2% and 65.7%, respectively. There was no association between the demographic factors of age, sex, or the reason for being monitored with the level of engagement ( P > .05).CONCLUSION:In this pilot study, patients with cancer were readily enrolled in a remote home monitoring program. Monitoring was feasible, and there was a high rate of engagement with the program. The role of RPM should be further tested as the COVID pandemic continues.
Approach to the History and Evaluation of Vertigo and Dizziness
Authors: Fife Terry D. 
Published: April 2021

ABSTRACT

PURPOSE OF REVIEW
This article reviews a method of obtaining the medical history of patients presenting with dizziness, vertigo, and imbalance. By combining elements of the history with examination, the goal is to identify patterns and an effective differential diagnosis for this group of patients to help lead to an accurate diagnosis.

RECENT FINDINGS
Studies over the past dozen years have changed the historical approach to patients with dizziness from one based primarily on how the patient describes the sensation of dizziness. This older approach can lead to misdiagnosis, so a preferred method puts greater emphasis on whether the dizziness is acute or chronic, episodic or continuous, or evoked by or brought on by an event or circumstance so that a pattern may be derived that better narrows the differential diagnosis and focused examination can further narrow to a cause or causes.

SUMMARY
Dizziness is a common symptom of many possible causes. This article will help clinicians navigate gathering the history and examination to formulate a working diagnosis in patients affected by dizziness.
Tinnitus, Hyperacusis, Otalgia, and Hearing Loss
Authors: Fife Terry D. , Tourkevich Roksolyana 
Published: April 2021

ABSTRACT

PURPOSE OF REVIEW
This article reviews the causes of tinnitus, hyperacusis, and otalgia, as well as hearing loss relevant for clinicians in the field of neurology.

RECENT FINDINGS
Important causes of unilateral and bilateral tinnitus are discussed, including those that are treatable or caused by serious structural or vascular causes. Concepts of hyperacusis and misophonia are covered, along with various types of neurologic disorders that can lead to pain in the ear. Hearing loss is common but not always purely otologic.

SUMMARY
Tinnitus and hearing loss are common symptoms that are sometimes related to a primary neurologic disorder. This review, tailored to neurologists who care for patients who may be referred to or encountered in neurology practice, provides information on hearing disorders, how to recognize when a neurologic process may be involved, and when to refer to otolaryngology or other specialists.
Novel Use of a Pyridinium Salt to Form a Solid Electrolyte Interphase (SEI) on High Voltage Lithium-Excess Layered Positive Active Material
Authors: Shomura Ryo , Sakakibara Keita , Marukane Shoko , Nakamichi Kimiyo , Morinaga Takashi , Tsujii Yoshinobu , Sato Takaya 
Published: April 2021

Abstract
Lithium-excess layered positive electrodes containing Fe and Ni are promising materials for the next generation of high voltage lithium ion batteries (LIB) because they are more chemically stable than those using Co and use more widely available metals. However, a positive electrode driven with a high voltage generates an electrochemical decomposition reaction of the electrolyte at the electrode interface and a significant deterioration in performance occurs. In order to suppress electrolysis of the electrolyte solution, a promising solution is to form a solid electrolyte interphase (SEI) on the electrode to mediate contact between the electrolyte solution and the electrode. In this study, we discovered that a pyridinium series salt, an ionic liquid, used as an additive, forms a good SEI on the positive electrode surface to improve the overall performance of the LIBs, such as improved cycle capacity and inhibited gas generation. Furthermore, from XPS, TOF-SIMS, 1H NMR and SEM measurements, we discuss the chemical makeup of the SEI and its formation mechanism, and propose a powerful method to achieve the next generation of high energy-density lithium ion batteries.
A 5-year-old Snowboarder with Boot Top Tibial Diaphysis Fracture
Authors: Prill Christine , Hoefler Amanda Honsvall 
Published: April 2021

Abstract
A previously healthy 5-year-old boy presented with an oblique fracture of the midtibial diaphysis at the top border of the snowboarding boot after falling from a standing position with both feet strapped to his snowboard. This case illustrates a snowboarding-specific variant of the torsion-tension boot top injury classically described in skiers. Unlike most snowboarding-related lower-extremity injuries, this fracture occurred in the absence of high-speed trauma or collision.