bluuebunny/crossref_metadata_2025_split huggingface dataset:
The level of reactive oxygen species production by adipocytes of epicardial adipose tissue is associated with an increase in postprandial glycemia in patients with severe coronary atherosclerosis
Authors: Koshelskaya O. A. , Naryzhnaya N. V. , Kologrivova I. V. , Suslova T. E. , Kharitonova O. A. , Evtushenko V. V. , Andreev S. L. , Gorbunov A. S. , Gudkova A. A. 
Published: October 2021

The mechanisms of oxidative stress in adipocytes of local fat depots in patients with cardiometabolic diseases have been studied insufficiently.Purpose. To study the levels of reactive oxygen species (ROS) production in adipocytes of epicardial (EAT) and subcutaneous adipose tissue (SAT) in patients with stable coronary artery disease (CAD) and severe coronary atherosclerosis who underwent coronary artery bypass grafting; to investigate the potential relationships between the levels of ROS production by EAT and SAT adipocytes and obesity parameters, EAT accumulation, basal and postprandial glycemia, and blood lipid transport function.Material and Methods. The study included 19 patients (12 men and 7 women including 6 patients (31.5%) with type 2 diabetes mellitus) aged 53–72 years with stable CAD and severe coronary atherosclerosis. The material for the study was EAT and SAT adipocytes obtained by the enzymatic method from intraoperative explants. The ROS level in adipocytes was determined using the fluorimetry with 2,3-dihydrodichlorofluorescein diacetate. Anthropometric parameters of obesity and EAT thickness were studied using echocardiography. The blood lipid transport function and the levels of basal and postprandial glucose were assessed.Results. The levels of ROS production by EAT and SAT adipocytes in the overall group of patients did not differ significantly and amounted to 1710 (1608; 2079) and 1876 (1374; 2215) arbitrary units, respectively. The level of ROS production by SAT adipocytes did not correlate with the parameters of obesity, EAT thickness, or biomarker levels. The level of ROS production by EAT adipocytes directly correlated with the level of postprandial glycemia (rs = 0.62, p < 0.05), but did not correlate with measures of general and abdominal obesity, EAT thickness, and dyslipidemia. The level of ROS production by EAT adipocytes in patients with postprandial glycemia ≥ 7.7 mmol/L (n = 9) exceeded the corresponding value in patients with lower level of postprandial glycemia (n = 10): 2079 (1710; 2458) against 1625.5 (1332; 1699) arbitrary units (p = 0.015), respectively.Conclusion. We showed for the first time that the level of ROS production by EAT adipocytes in CAD patients with severe coronary atherosclerosis was directly associated with the level of postprandial glycemia. The highest level of ROS production in EAT adipocytes occurred in these patients when the level of postprandial glycemia exceeds 7.7 mmol/L.
Significance of abdominal obesity and endothelial dysfunction marker in patients undergoing elective coronary stenting
Authors: Svarovskaya A. V. , Kuzheleva E. A. , Ogurkova O. N. , Garganeeva A. A. 
Published: October 2021

Aim. To study the prognostic significance of abdominal obesity and endothelial dysfunction marker in patients undergoing elective coronary stenting.Material and Methods. The study included 225 patients with coronary artery disease at an average age of 57 [51; 63] years admitted to hospital for the purpose of performing planned endovascular myocardial revascularization through stenting. Depending on the presence or absence of adverse cardiovascular events, the patients were divided into two groups. Group 1 included 127 patients with an unfavorable course of disease; group 2 comprised 98 examined patients with a favorable course. The serum levels of endothelin-1 (ET-1), insulin, interleukin-1 (IL-1), interleukin-6 (IL-6), and interleukin-10 (IL -10) and the ratio of waist to hip circumference (waist-to-hip ratio) were assessed directly before stenting the coronary arteries. The insulin resistance index (HOMA-IR) was calculated using the formula: fasting insulin (μIU/mL) × fasting blood glucose (mmol/L)/22.5. The lipid spectrum was determined by the enzymatic colorimetric method.Results. Correlation analysis of data in group 1 showed the presence of strong relationships of waist-to-hip ratio with body mass index (BMI) (r = 0.776; p = 0.000), ET-1 (r = 0.873; p = 0.000), and HOMA-IR index (r = 0.544; p = 0.000); weak relationships were found with basal glycemia (r = 0.238; p = 0.019), IL-10 (r = 0.295; p = 0.006), and IL-1 (r = 0.219; p = 0.047). Correlation analysis of data in group 2 showed the presence of week relationships of waist-to-hip ratio with BMI (r = 0.371; p = 0.002) and ET-1 (r = 0.471; p = 0.000) only.Conclusion. The study showed that ET-1 and the waist-to-hip ratio are strongly associated with the risk of adverse cardiovascular events after coronary stenting compared with other markers studied.
Pemicuan Sanitasi Total Berbasis Masyarakat (STBM) Pilar BABS di Kota Sibolga
Authors: Hasibuan Rapotan , Susilawati Susilawati , Nanda Meutia 
Published: October 2021

<p>Community Led Total Sanitation (CLTS) coverage in Sibolga city is still relatively low. This article aims to reconstruct the residents' understanding of the pillars of open defecation free (ODF) in Huta Tonga-Tonga Village, North Sibolga District. This activity is important to do in connection with the results of environmental observations and interviews with residents and health workers which highlight the understanding of personal hygiene and regional geographic conditions as the main obstacles. The socialization method was used in this work were lecturing in the form of counseling, measuring the volume of feces, compiling a flowchart of contamination by residents. The extension method is equipped with making BABS mapping, proper handwashing, and discussion of questions and answers with content of triggering elements. The resulting output is in the form of increased understanding of the importance of changing the behavior of open defecation and awareness of the potential diseases it can cause. In addition, the output can also be seen from the ability of residents to compile a fecal contamination flowchart. The follow-up of this activity is that the Health Office, the Sub-district side, the Puskesmas, and the Village Head should monitor and evaluate the results of the STBM triggering until finally the Huta Tonga-Tonga Village actually becomes a ODF Village.</p>
Monitoring quality of life in the first half­year period of coronaviral infodemy in Ukraine
Authors: Fedorenko O.E. , Koladenko K.V. , Sologub L.V. 
Published: October 2021

The COVID-19 pandemic, political and economic factors, the latest technological advances, environmental changes in the world — all this significantly influenced the awareness of the quality of life by most of the population. For us, as clinicians and lecturers of the Department of Dermatology and Venereology with a course of cosmetology at Bogomolets National Medical University, this became obvious after the forced abandonment of the usual «live» teaching and the transition to distance learning at Zoom in March 2020, and at the same time the re-profiling of the clinical base of the department for inpatient treatment of only COVID-19 patients with the simultaneous discharge of specialized dermatological patients.During the pandemic, we were in fact deprived of the possibility of further professional contact with specialized patients with dermatological diseases. We only had the technical ability to contact the 4th year students of NMU online. It was decided to take advantage of this opportunity not only for their distance teaching of the basics of dermatovenerology, but also for determining (clarifying) their psychostatus with the help of appropriate tests.
Objective — to conduct a remote monitoring study of the quality of life (QOL) indicators in young medical workers (students) against the background of the negative informative influence of the media due to the forced long-term stay in a stressful situation of lockdown and strict multi-week quarantine caused by the COVID19 pandemic.
Materials and methods. QOL was assessed using the Health Status Survey (SF36) which is one of general (non-specialized) questionnaires.
Results and discussion. During the period from March to June, there were noticeable changes in the self-esteem of somatically quite healthy fourth-year medical students of their own QOL, both on several SF-36 scales and in general. This was despite the fact that none of them and their family members were infected with COVID-19 or had any clinical manifestations of this disease for all 3 months. In general, during this time, the existing changes were negative, albeit to varying degrees, according to individual scales. In conditions of remote contact, it became technically possible and scientifically justified to use questionnaires to determine QOL in statistically significant samples of voluntary respondents.
Conclusions. We find it hypothetically possible to consider changes in QOL self-esteem in general and according to individual SF-36 scales as a kind of unconventional but quite objective and visual diagnostic test for preclinical (early) determination of the threat of formation and development of psychosomatic disorders in any adult patient who saw a family doctor.
Traveling with Trained Man
Authors: Maher Katie 
Published: October 2021

Abstract
This article considers the railways as a decolonial option for moving toward mobility justice. It views the photographic artwork Trained Man by Ngalkban Australian artist Darren Siwes through a mobilities lens, considering how the artist plays with time and attends to space, making visible what colonial projects of protection and assimilation have attempted to erase. Attending to the truths and imaginaries that reside and move with Trained Man, it draws on the work of Aboriginal and Black artists, scholars, and activists to trace Australia's past and present colonial history of training Aboriginal people into whiteness. It considers the railways as carrying “two lines of destiny” with potential moving in both colonial and decolonial directions. The article concludes by suggesting that shared spaces such as the railways open possibilities for mobilizing the decolonial project.
Book Reviews
Authors: Baker Lucy , Castañeda Paola , Dalstrom Matthew , Datta Ankur , Joelsson Tanja , Jordi-Sánchez Mario , Kelly Jennifer Lynn , Zunino Singh Dhan 
Published: October 2021

Nicholas A. Scott, Assembling Moral Mobilities: Cycling, Cities and the Common Good (Lincoln: University of Nebraska Press, 2020), 288 pp., 38 illus., $50
John Stehlin, Cyclescapes of the Unequal City: Bicycle Infrastructure and Uneven Development (Minneapolis: University of Minnesota Press, 2019), 328 pp., 24 photos, 11 maps, 9 tables, $27
Cecilia Vindrola-Padros, Critical Ethnographic Perspectives on Medical Travel (New York: Routledge, 2019), 161 pp., $36.77
Nicola Frost and Tom Selwyn, eds., Travelling Towards Home: Mobilities and Homemaking (New York: Berghahn, 2018), 182 pp., 10 illus., 1 table, $110
Peter Cox, Cycling: A Sociology of Vélomobility (Abingdon: Routledge, 2019), 200 pp., 2 B/W illus., £120.00 (ebook £40.49)
Lesley Murray and Susana Cortés-Morales, Children's Mobilities: Interdependent, Imagined, Relational (London: Palgrave Macmillan, 2019), 307 pp., 10 illus., $89.99
Jocelyne Guilbault and Timothy Rommen, eds., Sounds of Vacation: Political Economies of Caribbean Tourism (Durham, NC: Duke University Press, 2019), 234 pp., $25.95
John Krige, ed., How Knowledge Moves: Writing the Transnational History of Science and Technology (Chicago: The University of Chicago Press, 2019), 408 pp., 11 illus., $40
State of Uncertainty
Authors: Wentzel Sigrid Irene 
Published: October 2021

Abstract
In July 2019, the village of Nizhniy Bestyakh in the Republic of Sakha (Yakutiya), the Russian Far East, was finally able to celebrate the opening of an eagerly awaited railroad passenger connection. Through analysis of rich ethnographic data, this article explores the “state of uncertainty” caused by repeated delays in construction of the railroad prior to this and focuses on the effect of these delays on students of a local transportation college. This college prepares young people for railroad jobs and careers, promising a steady income and a place in the Republic's wider modernization project. The research also reveals how the state of uncertainty led to unforeseen consequences, such as the seeding of doubt among students about their desire to be a part of the Republic's industrialization drive.
3D-printed Poly-Lactic Co-Glycolic Acid (PLGA) scaffolds in non-critical bone defects impede bone regeneration in rabbit tibia bone
Authors: Lim Jin Xi , He Min , Chong Alphonsus Khin Sze 
Published: October 2021

BACKGROUND: An increasing number of bone graft materials are commercially available and vary in their composition, mechanism of action, costs, and indications. OBJECTIVE: A commercially available PLGA scaffold produced using 3D printing technology has been used to promote the preservation of the alveolar socket after tooth extraction. We examined its influence on bone regeneration in long bones of New Zealand White rabbits. METHODS: 5.0-mm-diameter circular defects were created on the tibia bones of eight rabbits. Two groups were studied: (1) control group, in which the bone defects were left empty; (2) scaffold group, in which the PLGA scaffolds were implanted into the bone defect. Radiography was performed every two weeks postoperatively. After sacrifice, bone specimens were isolated and examined by micro-computed tomography and histology. RESULTS: Scaffolds were not degraded by eight weeks after surgery. Micro-computed tomography and histology showed that in the region of bone defects that was occupied by scaffolds, bone regeneration was compromised and the total bone volume/total volume ratio (BV/TV) was significantly lower. CONCLUSION: The implantation of this scaffold impedes bone regeneration in a non-critical bone defect. Implantation of bone scaffolds, if unnecessary, lead to a slower rate of fracture healing.
Aspek biopsikososial ibu hamil bersalin dan nifas terkonfirmasi covid-19: Rapid review
Authors: Syah Putri Silvia Rizki , Pratiwi Cesa Septiana , Kurniawati Herlin Fitriani , Rosida Luluk 
Published: October 2021

World Health Organization (WHO) menyebut coronavirus disease yang ditemukan pertama kali di Wuhan dengan novel coronavirus 2019 (2019-nCoV) yang disebabkan oleh virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Ibu hamil, bersalin, nifas dan bayi baru lahir juga merupakan sasaran yang rentan terhadap infeksi Covid-19 (Kemenkes RI, 2020).Tujuan dari Rapid Review ini adalah untuk mengetahui ibu hamil, bersalin dan nifas yang terkonfirmasi Covid-19.Dari 12 Artikel yang didapatkan ibu hamil, bersalin dan nifas terkonfirmasi Covid-19 dilihat dari aspek biologi, aspek psikologi dan aspek sosial. Tetapi masih diperlukan untuk mengivestigasi mendalam terkait pengalaman ibu hamil, bersalin dan nifas terkonfirmasi Covid-19.
"PUBLISH OR PERISH": JAVANESE LANGUAGE MAINTENANCE ON JAVANESE-ENGLISH CODE-SWITCHING SONG
Authors: Maharani Amalina , Sudarwati Emy 
Published: October 2021

This descriptive qualitative study aims to shed new light on Javanese language maintenance through the practice of English-Javanese code-switching reflected in a song entitled Lathi by Weird Genius feat Sara Fajira. The intrinsic merit of the song 'Lathi,' covering cultural values, song lyrics significance, and the song's moral message, were deliberately discussed here. The data are taken from interview transcripts, observation, and documentation. The data were analyzed by first classifying the Lathi song lyrics into types of code switching, investigating the youths’ perception regarding the used of Javanese English code switching in Lathi song, and analyze the aspects of the songs highlighted the idea of Javanese language maintenance. The findings of this study suggest that the phenomenon of code-switching in Lathi songs is deliberately done to keep maintaining Javanese's existence as one of the popular vernacular in Indonesia. Language maintenance of the Javanese language in a song named Lathi can pique the public's interest in learning Javanese by creating Javanese language maintenance represented in its song lyrics. It makes the Javanese language gain popularity in the community, particularly among students and young people. It is, of course, a good sign of minimizing the threat of language shift. The continuous use of the local language as a language maintenance effort will avoid losing the community's first language
Pemberian Terapi Jus Wortel Pada Penderita Hipertensi Di Desa Bauh Gunung Sari Lampung Timur
Authors: Suwarto Suwarto , Furqoni Prima Dian 
Published: October 2021

ABSTRAK Hipertensi merupakan masalah kesehatan dengan prevalensi yang tinggi, yaitu sebesar 25,8%, pengobatan farmakologi, penurunan Hipertensi Pada pasien hipertensi dpat dilakukan dengan pengobatan non farmakologi. Salah satu alternatif pengobatan non farmakologi pada pasien hipertensi adalah pemberian pola makan DASH yang kaya akan kalium dan kalsium; diet rendah natrium. JNC VII menyarankan pola makan DASH yaitu diet yang kaya dengan buah, sayur, dan produk susu redah lemak dengan kadar total lemak dan lemak jenuh .Natrium yang direkomendasikan < 2.4 g (100 mEq)/hari. Tujuan Asuhan Keperawatan Komprehensif Pada klien Hipertensi Dengan Terapi Komplementer Jus Wortel di Desa Bauh Gunung Sari Lampung Timur Tahun 2020. Metode terapi dengan Wortel diblender 150 gram ditambah ±100cc air mineral + 1 sendok makan madu (sebagai pemanis ) diberikan kepada responden sebanyak ±200gram /hari selama 5 hari berturut-turut pada pukul 13.00-15.00wib. masalah hipertensi teratasi dengan terapi jus wortel dengan hasil efektif pada kedua pasien hanya saja kadar penurunan tekanan darah dan waktu penurunan berbeda diantara kedua pasien dikarenakan intensitas nyeri antara kedua pasien, dan kadar tekanan darah kedua pasien yang berbeda. Kata Kunci : Hipertensi, Komplikasi, Terapi Jus Wortel ABSTRACT Hypertension is a health problem with a high prevalence, which is 25.8%, pharmacological treatment, hypertension reduction in hypertensive patients can be done with non-pharmacological treatment. One alternative non-pharmacological treatment in hypertensive patients is the administration of a DASH diet that is rich in potassium and calcium; a low sodium diet. JNC VII recommends the DASH diet, which is a diet rich in fruits, vegetables, and low-fat dairy products with total fat and saturated fat content. The recommended sodium is <2.4 g (100 mEq) / day. Purpose of Comprehensive Nursing Care for Hypertension clients with Complementary Carrot Juice Therapy in Bauh Gunung Sari Village, East Lampung in 2020. The therapeutic method with Blender Carrot 150 grams plus ± 100cc mineral water + 1 tablespoon of honey (as a sweetener) is given to respondents as much as ± 200gram / days for 5 consecutive days from 1:00 to 15:00 a.m. the problem of hypertension is resolved with carrot juice therapy with effective results in both patients except that the level of blood pressure drops and the time of decrease is different between the two patients due to the intensity of pain between the two patients, and the blood pressure levels of the two patients are different. Keywords: Hypertension, Complications, Carrot Juice Therapy
Pemberian Terapi Senam Kaki Pada Pasien Diabetes Mellitus Di Desa Gunung Labuhan Sungkai Selatan Lampung Utara
Authors: Apriyadi Apriyadi , Zainaro M. Arifki 
Published: October 2021

ABSTRAK Data Riskesdas Provinsi Lampung tahun 2013 jumlah penderita diabetes mellitus yang terdiagnosis dokter sebesar 0,7%. Prevalensi penderita diabetes mellitus di Lampung utara berada di posisi kelima terbanyak dengan jumlah 0,8%. Sementara jumlah penderita di Lampung yang terdiagnosis dan yang tidak terdiagnosis tetapi selama sebulan terakhir mengalami gejala-gejala diabetes mellitus berjumlah lebih besar yaitu 0,8% dengan prevalensi di Lampung utara sebesar 0,8%. Penatalaksanaan diabetes mellitus terdiri dari 5 pilar utama olahraga atau latihan fisik merupakan salah satu dari penatalaksanaan tersebut selain dari diet, obat-obatan, edukasidan pemantauan, Olah raga dalam arti gerak fisik atau kerja otot dapat meningkatkan metabolisme atau pembentukan dan pengeluaran energi tubuh, salah satunya yaitu senam kaki. Tujuan setelah penyuluhan dan demonstrasi, diharapkan pemberian senam kaki dapat untuk menurunkan kadar glukosa pada klien diabetes melitus. Adapun kegiatan yang dilakukan berupa penyuluhan menggunakan leaflet dan demonstrasi senam kaki. Terdapat penurunan kadar glukosa pada klien diabetes melitus setelah pemberian akupresur selama 7 hari di Desa gunung labuhan sungkai selatan, Lampung Utara. Dengan demikian, pemberian senam kaki pada klien diabetes melitus sangat efektif dalam menurunkan glukosa. Kata Kunci: Senam kaki, diabetes melittus ABSTRACT Lampung Province Riskesdas data in 2013 the number of people with diabetes mellitus diagnosed by doctors (0.7%). The prevalence of people with diabetes mellitus in northern Lampung is in the fifth position (0.8%). While the number of sufferers in Lampung who were diagnosed and those who were undiagnosed, during the last month experiencing symptoms of diabetes mellitus was greater, namely (0.8%) with a prevalence in northern Lampung (0.8%). Management of diabetes mellitus consists of 5 main pillars of sports or physical exercise is one of these treatments apart from diet, drugs, education, and monitoring, Sports in the sense of physical movement or muscle work can increase metabolism or the formation and expenditure of the body's energy, one of which is foot exercise. The aim after counseling and demonstration is expected to provide foot exercises to reduce glucose levels in clients with diabetes mellitus. The activities were carried out in the form of counseling using leaflets and foot exercises. There was a decrease in glucose levels in diabetes mellitus clients after giving acupressure for 7 days in the village of Gunung Labuhan, South Sungkai, North Lampung. Thus, giving foot exercises to diabetes mellitus clients is very effective in reducing glucose. Keywords: Foot exercises, diabetes Mellitus