bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pola Perilaku Hidup Bersih dan Sehat pada Tatanan Rumah Tangga di Kota Surabaya Indonesia
Authors: Fadila Rena Azizul , Rachmayanti Riris Diana 
Published: December 2021

ABSTRAKLatar Belakang: Salah satu program yang dapat digunakan untuk memampukan anggota keluarga dalam pelaksanaan PHBS adalah melalui program PHBS rumah tangga. Dengan program PHBS ini, keluarga akan turut berperan aktif pada gerakan kesehatan di masyarakat. Hasil survey berdasarkan data Dinas Kesehatan Kota Surabaya tahun 2018 menunjukkan sebanyak 68,74% rumah tangga di Kota Surabaya telah menerapkan Perilaku Hidup Bersih dan Sehat (PHBS), sedangkan target dari Kementrian Kesehatan sebanyak 70%. Tujuan: Penelitian ini bertujuan untuk menganalisis hubungan pengetahuan, dan sikap masyarakat di tatanan rumah tangga dalam menerapkan perilaku hidup bersih dan sehat sebagai salah satu upaya dalam peningkatan derajat kesehatan masyarakat.Metode: Penelitian ini menggunakan metode analitik, desain yang digunakan adalah korelasional, dan pendekatan yang digunakan menggunakan pendekatan cross-sectional. Penelitian ini dilakukan pada Januari 2020 di RW 9 Kelurahan Ujung. Populasi penelitian ini adalah ibu yang memiliki bayi usia 0-24 bulan sebanyak 85 orang. Penentuan sampel dalam penelitian ini dengan metode simple random sampling yaitu sebanyak 71 orang. Pengetahuan dan sikap merupakan variabel independen, sedangkan perilaku hidup bersih dan sehat merupakan variabel dependen. Pengolahan data dapam penelitian ini menggunakan uji Spearman.Hasil: Penelitian ini menunjukkan hasil bahwa p value pada variabel pengetahuan adalah 0,000 < α (0,05) dengan correlation coefficient p=0,678, sehingga dapat diartikan bahwa terdapat hubungan dengan keeratan yang kuat antara pengetahuan dengan PHBS. Sedangkan p value pada variabel sikap adalah p 0,000<α (0,05) dengan correlation coefficient p=0,705 yang menunjukkan adanya hubungan dengan keeratan yang kuat antara sikap dengan PHBS.Kesimpulan: Pengetahuan keluarga merupakan faktor utama pada penerapan PHBS di tatanan rumah tangga. Perlu adanya kerja sama antara lintas sektor untuk meningkatkan kegiatan penyuluhan dan emo demo guna meningkatkan pengetahuan masyarakat.Kata kunci: PHBS, perilaku, rumah tangga, pengetahuan, sikap
Hubungan Pengetahuan dan Kepatuhan Mengkonsumsi Tablet Tambah Darah dengan Kejadian Anemia Defisiensi Besi: Literature Review
Authors: Larasati Destania Kinthan , Mahmudiono Trias , Atmaka Dominikus Raditya 
Published: December 2021

ABSTRAKLatar Belakang: Prevalensi remaja putri yang mengalami anemia defisiensi besi di Indonesia masih tinggi. Di Indonesia angka kejadian anemia pada remaja putri mencapai 21.7%. Anemia pada remaja dapat mempengaruhi konsentrasi dalam belajar, rendahnya produktifitas, dan mudah terkena infeksi. Pemerintah menjalankan program pemberian tablet tambah darah untuk menanggulangi anemia defisiensi besi pada remaja,. Tablet tambah darah diberikan pada remaja putri Sekolah Menengah Pertama (SMP) dan Sekolah Menengah Atas (SMA, dilakukan satu minggu sekali. Namun, program ini dirasa kurang efektif karena kepatuhan konsumsi tablet tambah darah pada remaja putri masih rendah. Salah satu faktor yang mempengaruhi adalah rendahnya pengetahuan remaja tentang anemia. Rendahnya pengetahuan tentang anemia berhubungan erat dengan konsumsi dan kesadaran dalam mengkonsumsi tablet tambah darah Tujuan: Untuk mendiskusikan hubungan pengetahuan dan kepatuhan konsumsi tablet tambah darah dengan kejadian anemia pada remaja putri.Metode: Penulisan artikel ini adalah literature review dengan bersumber dari artikel yang diterbitkan dalam kurun waktu 10 tahun dan berhubungan dengan topik yang akan dibahas. Pencarian artikel melalui database Google Scholar dan Pubmed. Terdapat 25 artikel yang diperoleh, tetapi hanya 12 artikel yang dipilih untuk diulas karena sesuai dengan topik yang akan dibahas, tujuan, sasaran, dan hasil penelitianHasil: Dari beberapa artikel yang telah diulas menunjukkan bahwa pengetahuan remaja terkait anemia dan kepatuhan remaja dalam mengkonsumsi tablet tambah darah berhubungan dengan kejadian anemia yang dialami oleh remaja. Pengetahuan yang baik tentang anemia dan gizi akan mempengaruhi pola makan pada remaja sehingga dapat mencegah anemia. Selain itu, patuh mengkonsumsi tablet tambah darah juga akan mempengaruhi kadar hemoglobin pada remajaKesimpulan: Pengetahuan remaja terkait anemia dan patuh mengkonsumsi tablet tambah darah akan mempengaruhi kadar hemoglobin pada remaja. Kata kunci: anemia, pengetahuan, kepatuhan, tablet tambah darah, remaja putri
Sobre a possibilidade de uma terapia para a cultura
Authors: Souza Edson Siquara 
Published: December 2021

No O Mal-Estar da Civilização Freud deixa em aberto uma pergunta sobre a possibilidade de a cultura ser, ela própria, neurótica[1], e neste sentido, se não seria pertinente um tratamento para a cultura; mas a psicanálise surge para curar o indivíduo, que poderia, então, ser considerado saudável, mas tendo que se adaptar a uma cultura doente. Neste artigo tento identificar em Freud e Schiller as possibilidades de uma terapia para a cultura.

[1] “Se a evolução cultural tem tamanha similitude com a do indivíduo e trabalha com os mesmos recursos, não seria justificado o diagnóstico de que muitas culturas – ou épocas culturais, ou possivelmente toda a humanidade – tornaram-se ‘neuróticas’ por influência dos esforços culturais?” (2010, p.119/120)
LUGARES PERSISTENTES, PRÁTICAS FUNERÁRIAS E TECNOLOGIA CERAMISTA EM CAÇADORES-COLETORES PRÉ-HISTÓRICOS SUL-AMERICANOS: Uma Proposta de Interpretação para o Sítio Arqueológico Pedra do Alexandre, Carnaúba dos Dantas, RN, Brasil
Authors: Mafra Fabio 
Published: December 2021

A classificação do sítio Pedra do Alexandre como cemitério, insere-o no cerne das discussões sobre as práticas funerárias de grupos caçadores-coletores sul-americanos. Considerado como lugar persistente (persistente place) e marco paisagístico (landmark), neste artigo, apresentou-se uma síntese das pesquisas arqueológicas desenvolvidas. Como resultados obtidos, elenca-se: as novas cronologias definidas, as relações tecno-tipológicas com os outros sítios registrados e o surgimento da tecnologia ceramista, no assentamento. Além da proposição de um modelo de variação temporal para as práticas mortuárias e a definição de um horizonte cultural, com longa duração histórica, na área arqueológica do Seridó (RN, Brasil). PERSISTENT PLACES, FUNERARY PRACTICES AND CERAMIC TECHNOLOGY IN SOUTH AMERICAN PREHISTORIC HUNTERS-COLLECTORS: An Interpretation Proposal for the Archaeological site Pedra do Alexandre, Carnaúba dos Dantas, RN, Brazil ABSTRACTThe classification of the Pedra do Alexandre site as a cemetery inserts it at the heart of the discussions on the funerary practices of South American hunter-gatherer groups. Considered as a persistent place and a landmark, this article presents a synthesis of the archaeological research developed. As results obtained, it is listed: the new defined chronologies, the techno-typological relations with the other registered sites and the emergence of ceramic technology in the settlement. In addition to the proposition of a model of temporal variation for mortuary practices and the definition of a cultural horizon, with a long historical duration, in the archaeological area of Seridó (RN, Brazil).Key-words: Funerary Practices - Persistent Place; Hunter-gatherer ceramists groups
CENPF/CDK1 Signaling Pathway Enhances the Progression of Adrenocortical Carcinoma by Regulating the G2/M-phase Cell Cycle
Authors: Huang Yugang , Li Dan , Wang Li , Su Xiaomin , Tang Xian-bin 
Published: December 2021

Abstract
Adrenocortical carcinoma (ACC) is an aggressive and rare malignant tumor and prone to local invasion and metastasis. While, overexpressed Centromere Protein F (CENPF) is closely related to oncogenesis of various neoplasms, including ACC. However, the prognosis and exact biological function of CENPF in ACC remains largely unclear. In present essay, the expression of CENPF in human ACC samples, GEO and TCGA databases depicted that CENPF were overtly hyper-expressed in ACC patients and positively correlated with tumor stage. The aberrant expression of CENPF was significantly correlated with unfavorable overall survival (OS) in ACC patients. Then, the application of gene-set enrichment analysis (GSEA) declared that CENPF was mainly involved in the G2/M-phase mediated cell cycle and p53 signaling pathway. Further, a small RNA interference experiment was conducted to demonstrate that the interaction between CENPF and CDK1 enhanced the G2/M-phase transition of mitosis, cell proliferation and might induce p53 mediated anti-tumor effect in human ACC cell line, SW13 cells. Lastly, two available therapeutic strategies, including immunotherapy and chemotherapy, have been further probed. Immune infiltration analysis highlighted that ACC patients with high CENPF expression harbored significantly different immune cell populations, and high TMB/MSI score. Then, the gene-drug interaction network stated that CENPF inhibitors, such as Cisplatin, Sunitinib, and Etoposide, might serve as potential drugs for the therapy of ACC. Briefly, CENPF and related genes might be served as a novel prognostic biomarker or latent therapeutic target for ACC patients.
Energy, Economic, and Environmental Assessment of Coriander Seed Production Using Material Flow Cost Accounting and Life Cycle Assessment
Authors: Dekamin Majid , Kheiralipour Kamran , Afshar Reza Keshavarz 
Published: December 2021

Abstract
The agricultural sector in the world is facing social expectations to reduce energy consumption and environmental impacts; and at the same producing enough food and fiber for the growing world population. The purpose of the present research to determine the economic, energy consumption, and environmental indicators in coriander seed production using novel approach of material flow cost accounting (MFCA) along with classical life cycle assessment (LCA). The positive output and negative energy were 25485 and 6742 MJ ha−1, respectively. Energy efficiency, net energy gain, specific energy, and energy productivity indicators were calculated as 0.6, -11944 MJ ha−1, 17.4 MJ kg−1, and 0.06 kg MJ−1, respectively. The average production cost was calculated as 588 $ ha−1 (334 $ ton−1) whereas gross income was 1267 $ ha−1 (720 $ ton−1). The value of negative products in coriander production was estimated as 239 $ ha−1 (136 $ ton−1). Seed shedding at harvest and water loss due to inefficient irrigation system were found to be the major negative products (economic and energy) in the system that can enhance the system productivity upon improvement. The values of benefit costs ratio and economic productivity were 1.74 and 3 kg $−1, respectively. The acidification potential (58.2 kg SO2 eq ton−1), global warming potential (510 kg CO2 eq ton−1), photochemical oxidation potential (0.13 kg C2H4 eq ton−1), and eutrophication potential (23 kg PO4 −3 eq ton−1) indicators were evaluated. The hotspots in point of economic (labor and seed shedding), energy use (nitrogen fertilizer and machinery) and energy loss (seed shedding), and environment (diesel fuel consumption) were determined which can be used to optimize coriander production through decreasing the material and energy consumption in the field. The results showed that MFCA combined with LCA is a powerful tool in identifying hotspots in crop production systems and can be used in developing more sustainable systems as well as in developing sustainability models.
Changes in Chorioretinal Flow Index after Cataract Surgery: An Optical Coherence Tomography Angiography Study
Authors: Nemet Achia , Mimouni Michael , Haddad Fadi , Safuri Shadi , Achiron Asaf , Shapira Yinon , Mtanis Kamal , Duvdevan Nitzan , Ben-Ner Daniel , Zayit-Soudry Shiri 
Published: December 2021

Abstract
PURPOSE: Pseudophakic cystoid macular edema (CME) occurs in up to 2% of uneventful cataract surgeries. This study evaluates changes in macular blood flow succeeding uneventful phacoemulsification cataract extraction among otherwise visually healthy subjects.METHODS: This prospective study included 18 eyes of 18 patients undergoing routine phacoemulsification. Optical coherence tomography angiography (OCT-A) was performed using the Angio-Retina 6x6mm protocol with the XR Avanti Angio-Vue system (Optovue Inc., Fremont, California) prior to the surgery and 4-8 weeks thereafter. Exclusion criteria included motion artifacts, segmentation errors and signal strength index (SSI) ˂40. The main outcome measure was change in flow index (FI) measured in all 4 retinal segmentation layers within an area of 1mm diameter around the foveal center.RESULTS: Following surgery, a significant increase in SSI (46.65±8.62 versus 53.12±8.07, p=0.01), superficial plexus FI (0.98±0.23 versus 1.16±0.16, p=0.02) and deep plexus FI (0.54±0.46 versus 0.93±0.39, p=0.01) was found. No significant changes were noted in the outer retina or the choriocapillaris. CONCLUSION: The study demonstrates a significant increase in FI in the superficial and deep retinal plexus following uneventful cataract surgery, with the greatest changes occurring in the latter. These findings corroborate evidence from structural imaging and support the vascular etiology of pseudophakic CME.
Procalcitonin as a Diagnostic Marker in Patients with Infectious Diseases
Authors: Ashitani Keigo , Kobayashi Takehito , Saito Kohei , Shiomi Rie , Miyaguchi Kazuya , Yokoyama Akira , Aoyagi Ryutaro , Noguchi Toru , Yamaoka Minoru , Iida Shin-ichiro , Tsuzuki Yoshikazu , Hirooka Nobutaka , Hashimoto Masayoshi , Miyakawa Yoshitaka , Imaeda Hiroyuki , Yamamoto Keiji , Nakamoto Hidetomo 
Published: December 2021

Abstract
Background: Procalcitonin levels have been shown to indicate severity of a disease, but there have been few reports about interpretation of procalcitonin levels between different diseases. This study was therefore carried out to investigate the usefulness of procalcitonin for clinical diagnosis, and for discriminating between bacterial and viral infection, between cystitis and pyelonephritis, and between acute upper respiratory inflammation and pneumonia.Methods: Among patients with the primary complaint of fever who were treated, either hospitalized or as out-patients, at Saitama Medical University Hospital during a 5-year period from August 1, 2012, to July 31, 2017, the potential subjects for this study were the 362 patients, consisting of 191 males and 171 females, with whom procalcitonin was measured. The subjects with whom comparative evaluation was carried out were the 205 with whom the final diagnoses were diseases, these being infectious diseases, malignancies, collagen diseases, and benign tumors with 176, 12, 11 and 6 patients, respectively. The remaining patients were excluded from the study, these consisting of 150 patients with whom the final diagnosis was merely symptoms such as headache, or was a condition not covered by internal medicine, such as traumas; and 7 patients whose diagnoses were unknown.Results: Procalcitonin levels in patients with infectious diseases were significantly higher (p < 0.05) than in patients with malignant tumors, collagen diseases, or benign tumors. Comparison between different diseases showed significant differences (p < 0.05) between pyelonephritis and cystitis, and between bacterial pneumonia and acute upper respiratory inflammation.Conclusions: Procalcitonin was significantly elevated in patients with bacterial infection. Significant differences in procalcitonin level were found between pyelonephritis and cystitis, and between bacterial pneumonia and acute upper respiratory inflammation, so procalcitonin is considered to be useful for discrimination between these.
Molecular Variation Between RT-PCR Detected Rotavirus Infection of Naturally Diarrheic Neonatal Calves and Rotavirus Strains of Commercial Vaccines
Authors: ZAITOUN AHMED M.A. , Abdel-rady Ahmed , YOUSSEF ZAINAB M.A. 
Published: December 2021

Abstract
Neonatal diarrhea is the main cause of morbidity and mortality in calves, and Rotavirus is the main viral etiology. Rotavirus vaccines are one of the main important methods for control of diarrhea in neonates' calves. In the current study, Deoxyribonucleic acid (DNA) sequencing and phylogenetic analysis of Bovine Rotavirus Group A (BRVA) were performed in our study. 1 Calf guard® vaccine genotype (G6P1) and 5 different field genotypes (2 G6P5, 1 G10P5, G10P? and 1 G10P11) were subjected to DNA sequencing. We observed that at the nucleotide level, G10P5 and G10P? sequences were 100 % identical with each other, two G6P5 sequences were 100% identical with each other and there was no significant similarity between sequences of G10P11 with sequences of G6P5, G10P5, and G10P? The phylogenetic analysis of G10P5 and G10P? isolates showed a close cluster with G10 isolates of Sharkia governorate, Egypt, phylogenetic analysis of two G6P5 and one G10P11 isolate showed a close cluster with the VP4 gene of Rotavirus isolates of Dakahlia governorate, Egypt. Molecular comparison between detected and typed Rotaviruses' genotypes with other genotypes of common vaccines indicated that there were genetically close or distance between field and vaccine Rotavirus strains.
Growth strategy for two-dimensional nanomaterials via a unified model
Authors: chen zongkun , Schmid Ralf , Wang Xingkun , Fu Mengqi , Han Zhongkang , Scheer Elke , Huang Minghua , Nielaba Peter , Coelfen Helmut 
Published: December 2021

Abstract
Two-dimensional (2D) materials prepared by a wet-chemical precipitation route exhibit many unique properties and high potential in various fields. Still, simple, rational and green fabrication of target materials remains challenging due to the lack of a guiding principle. Here, we propose a universal qualitative model for 2D materials grown for layered and non-layered crystal structures by wet-chemical precipitation, which is confirmed by both theoretical simulation and experimental results. It demonstrates that 2D growth can be obtained by only tuning reaction concentration and temperature. This model not only has been applied to fabricate more than 30 different 2D nanomaterials in water at room temperature in the absence of additives, but also is promising in optimizing the experimental design of numerous other 2D nanomaterials.
Amycolatopsis Camponoti Sp. Nov., New Tetracenomycin-Producing Actinomycete Isolated from Carpenter Ant Camponotus Vagus
Authors: Zakalyukina Yuliya V , Osterman Ilya A , Wolf Jacqueline , Neumann-Schaal Meina , Nouioui Imen , Biryukov Mikhail 
Published: December 2021

Abstract
An actinobacterial strain A23T, isolated from adult ant Camponotus vagus collected in Ryazan region (Russia) and established as tetracenomycin X producer, was subjected to a polyphasic taxonomic study. Morphological characteristics of this strain included well-branched substrate mycelium and aerial hyphae fragmented into rod-shaped elements. Phylogenetic analyses based on 16S rRNA gene and genome sequences showed that strain A23T was most closely related to Amycolatopsis pretoriensis DSM 44654T (99.9%). Average nucleotide identity and digital DNA–DNA hybridization values between the genome sequences of isolate A23T and its closest relative, Amycolatopsis pretoriensis DSM 44654T, were 39.5% and 88.6%, which were below the 70% and 95-96% cut-off point recommended for bacterial species demarcation, respectively. The genome size of the isolate A23T is 10,560,374 bp with a DNA G+C content of 71.2 mol%. The whole-organism hydrolysates contain arabinose and galactose as main diagnostic sugars as well as ribose and rhamnose. It contained MK-9(H4) as the predominant menaquinone and iso-C16:0, iso-C15:0, anteiso-C17:0 and C16:0 as the major cellular fatty acids. Based on the phenotypic, genomic and phylogenetic data, isolate A23T represents a novel species of the genus Amycolatopsis, for which the name Amycolatopsis camponoti sp. nov. is proposed, and the type strain is A23T (=DSM 111725T =VKM 2882T).
Critical evaluation of the Microbial Turnover to Biomass approach for the estimation of biogenic non-extractable residue
Authors: Trapp Stefan , Brock Andreas Libonati , Kastner Matthias , Schäffer Andreas , Hennecke Dieter 
Published: December 2021

Abstract
Background

Persistence is a key criterion for the risk assessment of chemicals. In degradation tests, microbial biodegradation of labeled test chemicals leads to the incorporation of the label in microbial biomass, resulting in biogenic non-extractable residues (bioNER), which are not considered as harmful in persistence assessment. The amount of bioNER can be estimated using the Microbial Turnover to Biomass (MTB) model. MTB estimates the biomass growth during productive degradation of a compound from theoretical growth yield and CO2-formation and gives an upper and a lower value for bioNER formation.
Results

We collected experimental data in order to test accuracy and precision of this estimation method. In total, 16 experimental studies were found in literature where bioNER was experimentally quantified. Hereof, 13 studies used the amount of label recovered from total amino acid (tAA) content as proxy for bioNER. Unfortunately, the comparison with experimental data was difficult due to the variety of employed methods. A conversion factor is required to extrapolate from tAA on bioNER, and this factor may vary during the experiment and between experiments. The bioNER formation for all compounds tested was calculated with the MTB method, and the outcome was compared to measured tAA as proxy for bioNER. The relation between predicted and measured bioNER was significant, but no better correlation was obtained than with CO2 to tAA. The mean absolute error of the prediction (low MTB versus tAA) was 5% (unit applied label, %aL). Large deviations between experimentally determined bioNER and the calculated result for some compounds may indicate problems in the experimental determination of bioNER.
Conclusions

MTB thus provides a robust model for determining of the potential amounts of biomass and bioNER formed from the degradation of organic chemicals.