bluuebunny/crossref_metadata_2025_split huggingface dataset:
Techniques to select site of insertion for a peripheral intravenous catheter with vessel locating devices using light, sounds or tactile actions (or palpations)
Authors: Higgins Niall , Iu Peter , Carr Peter , Ware Robert , Van Zundert André 
Published: January 2021

AbstractBackgroundApproximately 80% of patients admitted to acute hospitals have at least one peripheral intravenous catheter inserted during their admission, for the administration of fluids and medicines, and/or diagnostic tests, so the failure rate is concerning. New technology may decrease these rates even when used by inexperienced inserters. The choice of insertion site for an intravenous catheter is a known predictor of catheter failure. Therefore, the objective for this study was to evaluate the utility of vessel locating devices for novice clinicians to select catheter insertion sites in the forearm.MethodsAn inter‐subject incomplete counterbalanced research design was employed with healthy volunteers. Novice clinicians used either a vessel locating device using light or sound waves or they used palpation to identify relatively superficial veins in the forearm. This was compared to site selection performed by an expert clinician using palpation method only. Measurements of differences were analysed from photos of chosen sites. Bland–Altman agreement analysis was used to plot novice expert agreement. The STROBE checklist was followed in reporting this study (Techniques to select site of insertion for a peripheral intravenous catheter with vessel locating devices (Appendix S1)).ResultsA total of 32 novice clinicians used three vessel locating devices and a palpation technique. Novice clinicians did not choose more veins for optimum catheter placement when assisted with vessel locating devices compared to palpation techniques. All methods had a similar mean difference between novice and expert measurements and a similar percentage difference in distance from the expert choice. Bland–Altman agreement analysis did not identify any advantage for the novice with vessel locating devices over palpation.ConclusionVessel locating devices do not enhance the ability of novice clinicians any greater than palpation when selecting suitable forearm veins. If vessel locating device approaches are to be adopted in clinical practice to support better insertion outcomes then current PIVC teaching techniques should include structured vessel locating devices theory and practice.Relevance to clinical practiceSuccessful insertion of a peripheral intravenous catheter (PIVC) on the first attempt is a challenging procedure for nurses. Careful consideration of the selected site of insertion could modify this risk factor for catheter failure. The choice of PIVC insertion site by a novice clinician compared to an expert does not necessarily improve with the use of vein locating technology. While there is a range of technological devices available to assist with locating vessels, there needs to be more emphasis from educators on how to select an appropriate insertion site for intravenous therapy.
Hospital and unit variables of missed nursing care in acute care hospitals: A cross‐sectional study
Authors: Jarošová Darja , Gurková Elena , Zeleníková Renáta , Plevová Ilona , Janíková Eva 
Published: January 2021

AbstractAims and ObjectivesTo investigate hospital, unit and staff variables as the correlates of missed nursing care (MNC) in Czech hospitals.BackgroundThere is a considerable variability in patterns of MNC across different hospital, unit and staff characteristics.DesignA cross‐sectional study was conducted. The STROBE guidelines for reporting observational studies were followed for reporting of the research study.MethodsA sample of 513 nurses working in nine acute care hospitals was recruited. MNC activities were measured with the MISSCARE Survey. Data were analysed using descriptive statistics and univariate logistic regression.ResultsType of unit was confirmed as a significant predictor of MNC. Staff characteristics (nurses’ work position, level of education and perceived adequacy of unit staff) and hospital variables did not contribute significantly to MNC.ConclusionsThe study replicated the patterns of MNC across different conceptual approaches. MNC was influenced by work environment characteristics rather than individual staff variables.Relevance to clinical practiceThe results of this research showed that missed nursing care is influenced by work environment characteristics rather than individual staff variables.
Effectiveness of ultra‐long protocol on in vitro fertilization/intracytoplasmic sperm injection‐embryo transfer outcome in infertile women with endometriosis: A systematic review and meta‐analysis of randomized controlled trials
Authors: Liu Shuai , Xie Yi , Li Fei , Jin Lei 
Published: January 2021

AbstractObjectiveTo evaluate the effectiveness of ultra‐long protocol on reproductive and controlled ovarian hyperstimulation outcome in in vitro fertilization/intracytoplasmic sperm injection‐embryo transfer (IVF/ICSI‐ET) in infertile women with endometriosis versus long protocol.MethodsWe retrieved articles without language restrictions in the Elsevier ScienceDirect, Embase, Medline, PubMed, Web of Science, China National Knowledge Infrastructure, Wan Fang Data Knowledge Service Platform and China Science and Technology Journal Database from inception to August 2020. RCTs including the comparison of reproductive outcome of infertile patients with endometriosis who underwent ultra‐long protocol and long protocol were selected. Data extraction was conducted using RevMan 5.3.ResultsA total of nine RCTs in compliance with the standard literature were included. This meta‐analysis suggested that ultra‐long protocol with a 3‐month downregulation could increase clinical pregnancy rate of infertile women with endometriosis (RR=1.31, 95% CI:1.11 ~ 1.55, P = 0.002) versus long protocol. However, subgroup analysis found the different protocol provided no significant difference in improving clinical outcomes in patients with different disease stage of endometriosis.ConclusionThe ultra‐long protocol could improve the clinical pregnancy rate of infertile women with endometriosis compared with long protocol with a 3‐month downregulation. And ultra‐long protocol could be effective to increase the ongoing pregnancy rate compared to long‐protocol. But, the efficacy of ultra‐long protocol is not different between early and advanced stage of endometriosis.
The relationship between vitamin E level and premature ovarian insufficiency
Authors: Ma Linjuan , Chen Guili , Xu Wenxian , Chen Peiqiong , Lan Yibing , Huang Yizhou , Li Chunming , Zhou Jianhong 
Published: January 2021

AbstractAimThe aim of this study is to investigate the role of vitamin E in the etiology of premature ovarian insufficiency (POI).MethodsThis study included a total of 96 matched cases and controls, including the case group composed of 40 women with POI, and the control group composed of 56 women with normal menstrual cycles. Serum levels of vitamin E (also known as α‐tocopherol), total cholesterol, follicle stimulating hormone (FSH), luteinizing hormone (LH) and anti‐Müllerian hormone (AMH) were determined. The relationship of α‐tocopherol with FSH, LH and AMH levels in women were evaluated using regression models.ResultsWe found a negative association of α‐tocopherol levels with FSH and LH levels, and a positive correlation between a‐tocopherol and AMH levels in the whole study population. In this study, α‐tocopherol levels were significantly lower in women with POI than those in women with normal menstrual cycles.ConclusionVitamin E levels showed significantly statistical difference between the POI and control group (P < 0.001). Therefore, vitamin E is correlated to POI.
Predictors of recurrent gestational diabetes mellitus: A Japanese multicenter cohort study and literature review
Authors: Morikawa Mamoru , Yamada Takashi , Saito Yoshihiro , Noshiro Kiwamu , Mayama Michinori , Nakagawa‐Akabane Kinuko , Umazume Takeshi , Chiba Kentaro , Kawaguchi Satoshi , Watari Hidemichi 
Published: January 2021

AbstractAimTo clarify whether maternal characteristics or laboratory parameters could help predict the onset of recurrent gestational diabetes mellitus (GDM).MethodsWe enrolled 615 women with consecutive singleton deliveries at or after 28 GW from two perinatal medical centers between 2011 and 2019 and divided them into four groups according to whether they had GDM in the first and second pregnancies. The outcome of this study was to clarify the incidence and the predictors of recurrent GDM.ResultsWe found that among 72 women (11.7%) who had GDM during their first pregnancy, the rate of recurrent GDM was 47.2%. The 34 women (5.5%) with recurrent GDM gained significantly less weight in the first and second pregnancies and lost less weight between the first delivery and the second conception compared with those women without GDM in both pregnancies. Of women with GDM during the first pregnancy, 21 scored 2 or 3 (multiple) positive points on a 75‐g oral glucose tolerance test (OGTT) during their first pregnancies; the GDM recurrence rate among these women (66.7%) was significantly higher than that among the 51 women who scored 1 positive point (39.2%; p = 0.0411). During the first pregnancy, insulin administration therapy was significantly more frequent in women with recurrent GDM than in women without recurrent GDM (23.5% vs. 5.3%, p = 0.0396, respectively).ConclusionA predictor of recurrent GDM onset was a score of 2 or 3 positive points on the OGTT during the first pregnancy.
So close, and yet so far away: The dichotomy of the specific immune response and inflammation in psoriasis and atopic dermatitis
Authors: Schäbitz A. , Eyerich K. , Garzorz‐Stark N. 
Published: January 2021

AbstractCharacterization of the complex interplay between cytokines, chemokines and microorganisms has led to a better understanding of the pathogenesis of both psoriasis and AD and resulted in new therapeutics targeting distinct immune responses. Psoriasis and AD share many characteristics: they are highly prevalent, chronic, cause primarily skin inflammation, but are associated with comorbidities, and come with a devastating quality of life due to itch and stigmatization. However, the pathogenesis of psoriasis and AD is opposing – psoriasis is dominated by a Th17 immune response that causes neutrophil migration, induction of innate immunity and exaggerated epithelial metabolism. Leading cytokines of this Th17 immune response are IL‐17A and F, IL‐22 and TNF‐a. AD is characterized by Th2 immunity characterized by the signature cytokines IL‐4 and IL‐13 leading to an impaired epidermal barrier, dampened innate immunity and eosinophil migration. This review compares genetics, microbiome and T‐cell infiltrate and resulting epithelial response in psoriasis and AD. Whilst the antagonistic course of psoriasis and AD is confirmed by response to specific biologics targeting the key cytokines of inflammation in psoriasis and AD, respectively, clinically overlapping phenotypes are challenging in our daily clinical practice. We conclude this review by summarizing what is known about these mixed phenotypes and how the identification of clinically relevant endotypes and molecular‐driven decision‐making is the next step in the field of dermato‐immunology.
Retrospective Comparison of Postinsertion Maintenances Between Conventional and 3D Printed Complete Dentures Fabricated in a Predoctoral Clinic
Authors: Kim Tae Hyung , Huh Jung Bo , Lee Janet , Bae Eun‐Bin , Park Cheryl J. 
Published: January 2021

AbstractPurposeA retrospective study to analyze the clinical performance of 3D printed complete dentures in edentulous patients compared with conventional complete dentures regarding postinsertion visits and patient reported outcomes.Material and MethodsElectronic charts were reviewed to analyze 420 (maxilla 270, mandible 150) heat‐polymerized conventional complete dentures (CCD) inserted between July 1, 2015 and June 30, 2016 and 217 (maxilla 130, mandible 86) 3D printed complete dentures (PCD) inserted between July 1, 2017 and June 30, 2018. Number of remakes, number of postinsertion adjustments, type and number of repairs, and patient reported complications were compared between two types of complete dentures. The frequency of denture repair and patient reported complications were analyzed using chi‐square of independence test.ResultsThe frequency of pain and visible ulcer lesions in the maxilla was determined to be 46.67% with CCD and 36.15% in PCD (p = 0.047). There was no statistical significance in other items. The majority of esthetic concerns was dissatisfaction with the shape of dentures with CCD (4.67%) and they had statistically significant, less frequent, esthetic problems than PCD (11.63%) (p = 0.047).ConclusionsSimilar clinical performance was recorded between the two groups, but the overall pain and visible ulcer lesions were less in the printed complete dentures then the conventionally processed dentures. However, the esthetic aspect was better in conventionally processed complete dentures.
Nurse's practices and attitudes toward sexual health, wellbeing, and function in people receiving haemodialysis: A scoping review
Authors: Mckie Amanda L. , Green Theresa , Bonner Ann 
Published: January 2021

AbstractBackgroundSexual health, wellbeing, and function are important parts of a person's identity. Chronic diseases, such as kidney failure can alter, impair, and profoundly, affect sexual wellbeing and function.ObjectiveTo conduct a scoping review of studies about renal nurses’ practice and attitudes towards sexual health, wellbeing, and function in people with kidney failure receiving haemodialysis.MethodsUsing Arksey and O'Malley's framework, seven databases were searched (CINAHL, MEDLINE, EMBASE, OvidPsycINFO, Scopus, Cochrane library, and JBI library). The search included studies published in English from January 2009 to January 2020.ResultsFour studies met the review criteria (two cross‐sectional surveys and two qualitative). Role confusion in discussing sexual issues, lack of training, and education in addressing sexual concerns, personal, and workplace related barriers were four factors that emerged from the review of the studies. This review identified that renal nurses were uncomfortable and hesitant in initiating discussions about sexual health, wellbeing, and function with people receiving haemodialysis.ConclusionRenal nurses experience role confusion about whose responsibility it is to initiate and discuss sexual concerns with patients, as well as who's role is it to conduct sexual health assessments. Work related and personal barriers impeded nurses’ practice regarding sexual health, wellbeing, and function. Nurses working in renal units need knowledge and practical training about how to initiate and address sexual concerns in those affected by kidney disease.
In Their Own Words: Resources Needed by School Nurses to Facilitate Student Immunization Compliance
Authors: Hoke Alicia M. , Stuckey Heather L. , Keller Chelsea M. , Lu Zhexi , Hivner Elizabeth A. , Calo William A. , Strick Janine M. , Kraschnewski Jennifer L. 
Published: January 2021

ABSTRACTBACKGROUNDAll 50 states have school‐entry immunization requirements, and many also allow exemptions based on medical and non‐medical reasons. School nurses are responsible for managing student immunization compliance based on state policies, but lack standardized resources and guidance.METHODSPennsylvania school nurses (N = 21) participated in semi‐structured interviews regarding their strategies for communication and management of student immunization information, along with resources needed for practice improvement. Data were analyzed using descriptive content analysis.RESULTSNurses reported similarities in timelines used for communication of immunization requirements, but differences in mechanisms used to secure and manage immunization records. Nurses reported a need for clarity regarding exclusions and exemption policy implementation and requested standardized resources and guidance for navigating immunization compliance.CONCLUSIONSA need exists for standardized processes that support immunization compliance. Furthermore, nurses highlighted a need for additional training and enhanced networks to develop creative strategies for promoting immunization uptake among families.
Impact of the COVID‐19 pandemic on the well‐being of children with neurodevelopmental disabilities and their parents
Authors: Masi Anne , Mendoza Diaz Antonio , Tully Lucy , Azim Syeda Ishra , Woolfenden Susan , Efron Daryl , Eapen Valsamma 
Published: January 2021

AimsTo examine the impact of COVID‐19 pandemic on child mental health and socio‐emotional and physical well‐being (including sleep, diet, exercise, use of electronic media; care giver perceptions of symptoms of child neurodevelopmental disability [NDD] and comorbidities), and care giver mental health and well‐being, social support and service use.MethodsAn online cross‐sectional self‐report survey was distributed via disability service providers and support groups. Care givers of children aged 2–17 years with a NDD were invited to respond to questions on child symptom severity and well‐being, parent well‐being and service access and satisfaction.ResultsOverall, 302 care givers (94.7% female) completed the survey. Average child age was 9.7 years and 66.9% were male. Worsening of any child NDD or comorbid mental health symptom was reported by 64.5% of respondents and 76.9% reported child health and well‐being was impacted by COVID‐19. Children were viewing more television and digital media (81.6%), exercising less (68.0%), experiencing reduced sleep quality (43.6%) and had a poorer diet (32.4%). Almost one fifth (18.8%) of families reported an increase in the dosage of medication administered to their child. Parents reported COVID‐19 had impacted their own well‐being (76.1%). Over half of respondents were not satisfied with services received during COVID‐19 (54.8%) and just 30% reported that telehealth works well for their child.ConclusionTargeted interventions are required to address worsening child neurodevelopmental disability, mental health symptoms and poor diet, sleep and exercise patterns. Improved access to telehealth services is indicated, as is further research on barriers and enablers of effective telehealth services.
Evaluation of the combined effects of different dose levels of Zinc oxide with probiotics complex supplementation on the growth performance, nutrient digestibility, faecal microbiota, noxious gas emissions and faecal score of weaning pigs
Authors: Wang Huan , Kim Kun Phil , Kim In Ho 
Published: January 2021

AbstractThis study was conducted to assess the effects of different dose levels of zinc oxide (ZnO) combined with probiotics complex supplementation on the growth, performance, nutrient digestibility, faecal lactobacillus and Enterobacteria counts, noxious gas emissions and faecal score of weaned piglets. A total of 180 crossbred weaning pigs ([Yorkshire × Landrace] × Duroc; 6.61 ± 1.29 kg [mean ± SE]; 28 days old) were used in a 42‐day trial. All pigs were randomly allotted to 1 of 4 treatment diets based on initial BW and sex (9 replicate pens/treatment; 2 gilts and 3 barrows/pen). Dietary treatment groups were as follows: CON, basal diet +ZnO 3,000 ppm; BZS, basal diet +ZnO 2,100 ppm +0.1% SynerZymeF10; BZS1, basal diet +ZnO 1,200 ppm +0.1% SynerZymeF10; BZS2, basal diet +ZnO 300 ppm +0.1% SynerZymeF10. During the phase 3, decreasing the ZnO concentration led to a linear reduction in ADG (p = 0.044), and the ADG was lower (p < 0.05) in BZS2 compared with CON treatment during the whole experimental period. The effects of dietary ZnO with probiotics complex were not detected (p > 0.05) on nutrient digestibility, Lactobacillus and E. coli counts, faecal gas emissions and faecal scores. In conclusion, the diet supplementation of ZnO (1,200 ppm) with probiotics complex has been shown to have comparable efficacy to ZnO (3,000 ppm) diet on growth performance, nutrient digestibility, faecal microbiota, noxious gas emissions and faecal score of weaning pigs.
Rural Perceptions of Acute Care at Home: A Qualitative Analysis
Authors: Levine David M. , Desai Meghna P. , Ross Joseph , Como Natalie , Anne Gill Emily 
Published: January 2021

AbstractPurposeHospital‐level care at home in urban areas delivers low‐cost, high‐quality care. Few have attempted to deliver home hospital care in a rural environment, where traditional hospitals are often less equipped to deliver high‐quality care. Little is known about rural clinicians’ and patients’ perceptions regarding rural home hospital care and how the urban model might be adapted to fit rural circumstances.MethodsWe conducted semistructured qualitative interviews in the United States with a national purposive sample of practicing rural clinicians, a focus group with clinicians who care for rural patients, and interviews with rural patients. We coded these qualitative data into domains and subdomains.FindingsWe identified 4 domains: (1) current state of rural health care, (2) attitudes toward rural home hospital, (3) perceived barriers to implementing rural home hospital, and (4) perceived facilitators to implementing rural home hospital. Participants expressed challenges with current rural health care, including inefficient care coupled with poor access. Most felt rural home hospital care could offer benefits, including comfort, timeliness, and downstream outcomes such as readmission rate reduction. Rural patients were open to receiving acute care in their homes. Potential barriers included geographic accessibility, Internet connectivity, rural hospital politics, the culture of hospitalization, and the availability of skilled human resources.ConclusionsSignificant interest and optimism exist surrounding rural home hospital despite perceived barriers. Designing for and testing adaptations to the urban model will likely optimize benefits and minimize threats to a potential intervention.
Phylogenomics of Fargesia and Yushania reveals a history of reticulate evolution
Authors: Ye Xia‐Ying , Ma Peng‐Fei , Guo Cen , Li De‐Zhu 
Published: January 2021

AbstractReticulate evolution is a common and important driving force in angiosperm evolution. In this study, we analyzed the phylogenetic signals of genomic regions with different inheritance patterns to understand the evolutionary process of organisms using species‐rich Himalaya–Hengduan taxa of bamboos (Fargesia Franchet and Yushania Keng). We constructed phylogenetic trees using different sampling strategies and reconstruction methods based on genome skimming and double digest restriction‐site‐associated DNA sequencing data. We assessed the congruence of topologies generated from different datasets and employed several approaches to reveal the causes of phylogenetic incongruence, including the detection of hybridization and introgression using PhyloNetworks and the D‐statistic test (ABBA‐BABA test). We found that, in the plastome‐based phylogeny, Fargesia bamboos can be clustered into three groups and Yushania was nested within one of them, which contradicts the nuclear–double digest restriction‐site‐associated DNA sequencing‐based phylogeny. Moreover, the genetic variation of chloroplast DNA is significantly correlated with geographical distribution. The strong signal of incomplete lineage sorting, hybridization, introgression, and cytoplasmic gene flow found among genera and species suggests that reticulate evolution is the main cause for the phylogenetic incongruence between nuclear and chloroplast datasets. Our results add evidence that genomes with different inheritance patterns can reveal distinct evolutionary histories of species and suggest that reticulate evolution is prevalent in rapidly diversifying groups.