bluuebunny/crossref_metadata_2025_split huggingface dataset:
Teleneurorehabilitation Among Person with Parkinson's Disease in India
Authors: Garg Divyani , Majumdar Ritu , Chauhan Sonal , Preenja Ravi , Parihar Jasmine , Saluja Alvee , Dhamija Rajinder K. 
Published: June 2021

Objective:
We aimed to assess the feasibility of teleneurorehabilitation (TNR) among persons with Parkinson's disease (PD), considering difficulties imposed by the COVID-19 pandemic in access to healthcare, particularly in low-resource settings. The feasibility of TNR in India has not been formally assessed so far.

Methods:
We conducted a single-center, prospective cohort study at a tertiary center in India. Persons with PD with Hoehn & Yahr (H&Y) stages 1-2.5, who were not enrolled into any formal exercise program, were offered TNR as per a predesigned program for 12 weeks. Baseline and post-intervention assessment included Movement Disorders Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), part II and III, Parkinson's Disease Questionnaire (PDQ)-8 and Non-Motor Symptoms Scale (NMSS). We assessed adherence to TNR and problems expressed by patients/caregivers by means of open-ended surveys addressing barriers to rehabilitation.

Results:
We recruited 22 for TNR. Median age (interquartile range [IQR]) was 66.0 (44.0-71.0) years; 66.7% were H&Y stage 2.0. One patient died of COVID-19-related complications. Of the remaining 21, 14 (66.7%) had adherence of ≥75%; 16/21 (76.2%) patients had problems with attending TNR sessions as the family shared a single phone. Slow Internet speed was an issue among 13/21 (61.9%) of the patients. Other issues included lack of rapport, migration to distant hometowns and motor-hand impairment.

Conclusion:
Multiple challenges were faced in implementing a telerehabilitation program among persons with PD, exacerbated by the COVID-19 pandemic. These barriers were present at various levels: recruitment, adherence issues and maintenance. Future TNR programs must address these concerns.
Neurosyphilis, A True Chameleon of Neurology
Authors: Pujari Shripad S , Kulkarni Rahul V , Duberkar Dhananjay , Nirhale Satish , Nadgir Dattatraya , Dhonde Pramod , Sakale Tejas , Shembalkar Prafulla , Meshram Chandrashekhar 
Published: June 2021

Background:
Neurosyphilis (NS) is a rarely encountered scenario today. Manifestations are heterogeneous, and their characteristics have changed in the antibiotic era. A differential diagnosis of NS is not commonly thought of even with relevant clinical-radiological features, as it mimics many common neurological syndromes.

Objectives:
To study the manifestations of NS in the present era and the process of diagnosis.

Method:
The data of ten patients with NS was collected and analyzed. Their background data, clinical features, investigations, the process of reaching the diagnosis, management and outcomes were recorded.

Observations and Results:
The manifestations of NS in our cohort included six patients with cognitive decline/encephalopathy and one each with meningitis with cranial nerve palsies, cerebellar ataxia, myelitis and asymptomatic NS. The presence of Argyll Robertson pupil helped to clinch diagnosis in one patient. Treponemal tests were ordered in two patients only after alternative etiologies were looked at, to begin with, whereas in six patients treponemal test was requested as a part of standard workup for dementia/ataxia.

Conclusions:
NS dementia and behavior changes are mistaken for degenerative, vascular, nutritional causes, autoimmune encephalitis or prion disease. Meningitis has similarities with infective (tubercular), granulomatous (sarcoidosis, Wegener's), collagen vascular disease and neoplastic meningitis, and myelitis simulates demyelination or nutritional myelopathy (B12 deficiency). Rarely, NS can also present with cerebellar ataxia. Contemplate NS as one of the rare causes for such syndromes, and its early treatment produces good outcomes.
Feasibility and Determinants of Deprescription of Proton Pump Inhibitors in Patients with Typical Reflux Symptoms
Authors: Jain Mayank 
Published: June 2021

Background and Aims:
Proton pump inhibitors (PPIs) are commonly used drugs in the management of reflux symptoms. These drugs are frequently overused and have side effects on long term use. The present study was undertaken to determine the feasibility and determinants of deprescription of PPI in patients with typical reflux symptoms.

Materials and Methods:
This retrospective study recruited all patients, >18 years, with heartburn and/or regurgitation of more than 3-month duration. The severity of reflux was assessed with white light endoscopy and graded as per Los Angeles classification. All patients were advised lifestyle changes, aerobic exercises for >30 min/day, and dietary modifications. Follow-up details, including symptom resolution and drug requirement, were noted at 3 months after the initial visit.

Results:
A total of 106 patients formed the study cohort (males 60, median age 43 years [range 18–72 years]). Reflux esophagitis was noted in 32 cases (30%). Of these patients, 8 (25%) had Grade A esophagitis and the remaining had Grade B or beyond. Three-fourths of the patients were prescribed once a day PPI. On follow-up at 3 months, PPI therapy was stopped completely in 58 (54.7%) cases. Thirty-two (30.2%) and 16 (15.1%) patients were on on-demand PPI and continuous low dose therapy, respectively. A significantly higher proportion of patients with reflux esophagitis (30/32, 93.75%) could stop PPI at the end of 3 months. The need for on-demand PPI and continuous low dose therapy was higher in patients with nonerosive reflux disease (14 cases, 19%). In univariate analysis, use of alcohol (P = 0.04), smoking (P = 0.0006), presence of diabetes mellitus (P = 0.01), and presence of hiatus on endoscopy (P = 0.03) were the factors significantly associated with continued use of PPI at the end of 3 months. In multivariate analysis, smoking was the only factor independently associated with the continuation of PPI use after 3 months.

Conclusion:
Deprescription of PPI was achieved in 90 cases (84.9%) at 3 months. In univariate analysis, use of alcohol, smoking, presence of diabetes mellitus, and presence of hiatus are associated with continued PPI use at 3 months. In multivariate analysis, smoking was the only factor independently associated with the continuation of PPI use after 3 months.
Evaluation of Psychological Impact of COVID-19 on Health-Care Workers
Authors: Grover Sandeep , Mehra Aseem , Sahoo Swapnajeet , Avasthi Ajit , Rao T. S. Sathyanarayana , Vaishnav Mrugesh , Dalal P. K. , Saha Gautam , Singh Om Prakash , Chakraborty Kaustav , Janardran Reddy Y. C. , Rao Naren P. , Tripathi Adarsh , Chadda Rakesh K. , Mishra K. K. , Rao G. Prasad , Kumar Vinay , Gautam Shiv , Sarkar Siddharth , Krishnan Vijay , Subramanyam Alka 
Published: June 2021

Background:
Little information is available from India about the psychological impact of COVID-19 on helath-care workers.

Aim:
The current study aimed to evaluate the psychological issues among the health-care workers (HCW) during the COVID-19 pandemic.

Materials and Methods:
An online survey using Survey Monkey® platform was carried out to evaluate depression (using Patient Health Questionnaire-9), anxiety (using Generalized Anxiety Disorder Questionnaire-7), and other psychological issues (using a self-designed questionnaire).

Results:
The study sample comprised 303 participants with a mean age of 41.2 (standard deviation: 11.1) years. A majority of them were male (69%) and married (79.9%). Nearly half (46.2%) of the participants had either anxiety disorder or depression or both and 12.9% of HCW had suicidal behavior. Higher level of anxiety and depression scores were associated with being female, having undergone quarantine, directly involved in the care of COVID-19 patients, and younger age (<30 years). Higher prevalence of depression and anxiety disorder was seen in younger (<30 years) age group, being a doctor (compared to paramedics). In addition, higher prevalence of depression was seen in those who were directly involved in the care of patients with COVID-19 infection.

Conclusion:
About half of the HCWs are suffering from psychiatric morbidity, specifically anxiety, in the wake of the COVID-19 pandemic. There is a need to assess all the HCWs for psychiatric morbidity and provide them with psychological support.
Coping with COVID
Authors: Singh Virendra Vikram , Patra Priyadarshee , Singal Ankit 
Published: June 2021

Introduction:
The sudden and extended lockdown imposed by the government as an attempt to break the transmission chain of COVID disrupted the lives and plans of many. The impact on mental health of people is variable depending on the appraisal of the situation and the resources and coping strategies.

Aim and Objectives:
The aim of the study was to know the impact on mental health and coping strategies used by internet users dealing with the COVID-19 pandemic and involved difficulties in India.

Materials and Methods:
The survey was conducted using Google doc application. Tools included Generalized Anxiety Disorder-7 (GAD-7) questionnaire, Patient Health Questionnaire (PHQ), and brief COPE questionnaire.

Statistical Analysis:
Descriptive statistics were used to assess the sociodemographic characteristics, GAD-7, PHQ-2, and brief COPE scales. The group differences were analyzed using appropriate parametric or nonparametric tests for the quantitative variable and Chi-square/Mc-Nemar's test for categorical variables. The data were analyzed using SPSS software.

Results:
Three hundred and twenty six responses were analyzed. Nearly 35.3% screened positive for anxiety disorder and 12% for major depression. Respondents who were screened positive for anxiety disorder used active coping, denial, substance use, behavioral disengagement, planning, and self-blame more often than those screened negative. Those screened positive for major depression used all the coping strategies similar to anxiety disorder except for active coping more often than those who screened negative. While females used adaptive coping more frequently than males, respondents those engaged in essential services employed maladaptive coping less often.

Conclusions:
Acceptance, positive reframing, and positive coping were the most often employed strategies, while denial, self-blame, and substance use were least often employed.
Safety and feasibility of laparoscopic left hepatectomy for the treatment of hepatolithiasis in patients with previous abdominal surgery
Authors: Liu Lingpeng , Huang Yong , Ding Zigang , Xu Bangran , Luo Dilai , Xiong Hu , Liu Hongliang , Huang Mingwen 
Published: June 2021

Background:
The aim of the study was to compare the benefits and drawbacks of laparoscopic left hepatectomy (LLH) in patients with previous abdominal surgery (PAS) with those in patients without PAS and confirm the safety and feasibility of LLH as a treatment for patients with hepatolithiasis and PAS.

Materials and Methods:
This retrospective comparative study included 111 patients who underwent LLH for hepatolithiasis (with PAS, n = 41; without PAS, n = 70) from August 2017 to August 2019. Patients’ general information, surgical outcomes, hospital stay duration, hospitalisation cost, post-operative laboratory data and post-operative complications were evaluated.

Results:
No statistically significant difference was noted in the post-operative laboratory data between patients with and without PAS (P > 0.05). Longer operative times were required for patients with PAS than for those without PAS (P = 0.025). Hospitalisation cost, hospital stay duration, blood loss, open conversion and post-operative complications were not significantly different between patients with and without PAS (P > 0.05). No cases of mortality were noted.

Conclusions:
LLH is a safe and feasible treatment for patients with hepatolithiasis and PAS.
Socioeconomic and Demographic Profile of Autism Spectrum Disorder
Authors: Marella Shivaji , Sahu Samiksha , Mujawar Swaleha , Saldanha Daniel , Chaudhury Suprakash 
Published: June 2021

Background:
Autism spectrum disorder (ASD) is a multifactorial disorder resulting from genetic and nongenetic risk factors and their interaction. There is a paucity of data on the socioeconomic and demographic factors underlying ASD from India.

Aim:
The aim of this study was to evaluate the socioeconomic and demographic profile of ASD.

Materials and Methods:
Six hundred patients with behavioral complaints reporting to either psychiatric or pediatric outpatient departments were screened and validated as per Autism questionnaire (Childhood Autism Rating Scale [CARS]). Included patients were evaluated on socioeconomic and demographic scale the appropriate Child Behavior Checklist (CBCL).

Results:
Twenty-eight children out of 600 (4.66%) were found to have ASD. The average age at which parents first noticed symptoms was 16 months (range: 9–24 months). The mean age at first consultation for ASD symptoms was delayed for girls. A highly significant association between intelligence quotient (IQ) and a diagnosis of ASD was seen. The mean IQ of ASD patients (93.2 n = 28) was significantly lesser than either psychiatric diagnoses or no diagnosis. Even though all patients had an IQ >70, there were still 9/28 patients with a level 3 severity of ASD. A highly significant association between ASD diagnosis and CARS scores was seen. Out of the documented 26 presenting complaints, 17 were social impairment related and 9 related to repetitive patterns of behaviors. The clinical findings from the CBCL conform to a previously developed autism profile for CBCL.

Conclusion:
Children are taking longer than recommended for optimal outcome to receive a diagnosis. Girls were brought for consultation with the pediatrician later than the boys. Male preponderance in ASD with M: F ratio of 6:1 was highly significant. ASD was found higher in MSES and HSES families. Living in urban areas predicted higher severity. IQ was lesser than for other conditions in ASD.
Psychological distress among survivors of moderate-to-critical COVID-19 illness
Authors: Imran Javaria , Nasa Prashant , Alexander Leny , Upadhyay Surjya , Alanduru Veena 
Published: June 2021

Purpose:
Coronavirus disease-2019 (COVID-19) is predicted to have long-term sequelae on the physical and mental health of survivors. We aim to calculate the prevalence of psychological distress in moderate-to-critical survivors of COVID-19.

Materials and Methods:
The patients discharged from the hospital after moderate-to-critical COVID-19 were interviewed using e-mail at 30 and 60 days for anxiety, depression, and posttraumatic stress disorder (PTSD) using Generalized Anxiety Disorder-7, Patient Health Questionnaire-9, and PTSD Check List-5 questionnaire, respectively.

Results:
In 103 patients (96% were immigrant workers), the prevalence rate of clinically significant anxiety, depression, and PTSD was 21.4%, 12.7%, and 8.7% at day 30 and 9.5%, 7.1%, and 4.7% at day 60, respectively. There was significantly higher anxiety in patients of Indian nationality and depression with preexisting chronic illness.

Conclusion:
There is a high prevalence rate of clinically significant psychological distress among COVID-19 survivors, and we propose a formal psychiatric assessment and long-term follow-up.
Índice de citação: um estudo de caso sobre o periódico Ensino em Perspectivas
Authors: Fialho Lia Machado Fiuza , Neves Vanusa Nascimento Sabino 
Published: June 2021

O artigo versa sobre o índice de citação do Google Scholar, adotado como critério principal a ser considerado avaliação para as revistas de humanidades no quadriênio 2017-2020. O objetivo foi analisar os principais artigos que impactaram no índice h5 da revista Ensino em Perspectivas (EnPe). Desenvolveu-se uma pesquisa qualitativa, do tipo estudo de caso, que utilizou o perfil público da revista EnPe no Google Scholar como plataforma de coleta de dados. Os resultados demonstraram que índices h5, em 10 de junho de 2021, é igual a 6, pois havia 9 artigos citados 6 ou mais vezes. As análises possibilitam inferir que por ser uma revista com apenas um ano e meio de existência seus índices no Google são relativamente bons, bem como que as temáticas mais citadas eram variadas, versando sobre formação de professor, gênero, inclusão, gestão pública, dentre outras.
EFFECTS OF PHOSPHORUS AVAILABILITY ON NODULATION AND NITROGEN UPTAKE BY THREE LEGUME CROPS IN TWO GHANAIAN SOILS
Authors: Boateng Alex , Bennoah Emmanuel 
Published: June 2021

Purpose: A greenhouse study of Soybean, Cowpea and Pigeon Pea was made at University of Ghana, to determine the effects of phosphorus availability on nodulation and nitrogen uptake by the afore mentioned legumes in two Ghanaian soils, Adenta and Nzema series.
Methodology: Three P rates of 0mg, 50mg and 100mg P of TSP and TPR were applied to a kilogram of soil per pot in two soil series. The pots were arranged using Randomized Complete Block Design. GenstatR was used to do the statistical analysis.
Findings: The results from this study showed that with or without Triple Super Phosphate (TSP) or Togo Phosphate Rock (TPR), soybean did not form nodules in the Nzema soil but nodulated with TSP application in the Adenta soil. The absence of nodulation even with high P from TSP by soybean in Nzema soil is surprising but the observation in the Nzema soil may be attributed to the absence of soybean Rhizobium cells or insignificant numbers of these rhizobia. The improvement in the dry matter yield of pigeon pea and cowpea on Adenta soil and soybean on the Nzema soil at TPR50 and TPR100 show the importance of P application to dry matter yield of legumes. Significant difference that was shown by cowpea on Nzema soil could be attributed to the ability of the crop to desorp P from sparingly available P sources through exudation of high amounts of organic acid anions, mainly citrate.
Unique contributions to theory, practice and policy: In the soil, Rhizobium species must recognize their specific host before nodulation may take place and the absence of the appropriate Rhizobium species with the introduction of a legume into a given soil may result in no or poor nodulation. Low P availability is a challenge for crop species to nodulate since the rhizobia responsible for nitrogen fixation have a high P requirement. The toxicity of Aluminum to rhizobia may be due to inhibition of DNA replication because of binding of Aluminum to DNA. One factor that could have accounted for the better nodulation in soil is the higher acidity. The optimum pH for effective rhizobia growth in soils is between pH 6 and 7
Full flowering phenology of apple tree (&lt;i&gt;Malus domestica&lt;/i&gt;) in Pūre orchard, Latvia from 1959 to 2019
Authors: Kalvāne Gunta , Gribuste Zane , Kalvāns Andis 
Published: June 2021

Abstract. The Pūre orchard is one of the oldest apple orchards
in the Baltic, where thousands of varieties of fruit trees from throughout
the world are grown and tested. Over time, a huge knowledge base has been
accumulated, but most of the observational data are stored in archives in
paper format. We have digitized a small part of the full flowering
phenological data of apple trees (Malus domestica) over the period of 1959 to 2019 for 17
varieties of apple trees, a significant step for horticulture and
agricultural economics in Latvia. Climate change has led to significant
changes in the phenology of apple trees as all varieties, autumn, summer and
winter, have begun to flower earlier: from 2002 to 2019, on average full
flowering was recorded to have taken place around 21 May, whereas for the
period 1959–1967 it occurred around 27–28 May. To develop better-quality phenological predictions and to take account of
the fragmentary nature of phenological data, in our study we assessed the
performance of three meteorological data sets – gridded observation data
from E-OBS, ERA5-Land reanalysis data and direct observations from a distant
meteorological station – in simple phenological degree-day models. In the
first approximation, the gridded E-OBS data set performs best in our
phenological model.
Persistent effects of sand extraction on habitats and associated benthic communities in the German Bight
Authors: Mielck Finn , Michaelis Rune , Hass H. Christian , Hertel Sarah , Ganal Caroline , Armonies Werner 
Published: June 2021

Abstract. Sea-level rise demands for protection measures of endangered
coastlines crucial for the local population. At the island of Sylt in the SE
North Sea, shoreline erosion is compensated by replenishment with sand
dredged from an offshore extraction site. We studied the long-term effects
of sand extraction on bathymetry, geomorphology, habitats and benthic
fauna. Sand extraction created dredging holes about 1 km in diameter and up
to 20 m below the ambient seafloor level. Directly after dredging the
superficial sediment layer, inside the pits was dominated by coarse sand and
stones. Hydroacoustic surveys revealed only minor changes of bathymetry
> 35 years after sand extraction. Obviously, backfill of the
dredging pits was very slow, at a rate of a few millimeters per year, presumably
resulting from low ambient sediment availability and relatively calm
hydrodynamic conditions despite high wave energy during storms. Thus, a
complete backfill of the deep extraction sites is likely to take centuries
in this area. Hydroacoustic surveys and ground truthing showed that the
backfilled material is mainly very fine sand and mud, turning the previously
coarse sand surface into a muddy habitat. Accordingly, grab samples revealed
significant differences in macrozoobenthos community composition, abundance
and species density between recently dredged areas (< 10 years ago),
recovery sites (dredging activity > 10 years ago) and undisturbed
sites (control sites). Overall, dredging turned the original association of
sand-dwelling species into a muddy sediment association. Since
re-establishment of disturbed benthic communities depends on previous
re-establishment of habitat characteristics, the low sedimentation rates
indicate that a return to a pre-dredging habitat type with its former
benthic community and habitat characteristics is unlikely. Since coarse sand
is virtually immobile in this area, a regeneration towards pre-dredging
conditions is also unlikely without human interference (e.g., mitigation
measures like depositing coarse material on the seafloor to restore the
sessile epifauna).