bluuebunny/crossref_metadata_2025_split huggingface dataset:
DEVELOPMENT AND VALIDATION OF A UV SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF AGOMELATINE IN BULK AND A TABLET DOSAGE FORM
Authors: M. Firake Bhushan , V. Pathak Pranjalee , K. Dorik Pallavi , M. Siddaiah 
Published: February 2021

UV spectrophotometry is an analytical technique used routinely for qualitative and quantitative assay due the low cost and reliability during analysis. An simple, efficient, rapid, sensitive, precise and economical UV Spectrophotometric method has been developed for estimation of agomelatine from bulk and pharmaceutical formulation. The method was developed and validated according to International Conference on Harmonization (ICH Q2 R1) guidelines. The λmax of agomelatine in acetonitrile was found to be 229.6 nm. The analytical method validation parameters linearity, precision, accuracy, robustness were studied according to International Conference on Harmonization guidelines. Pure drug concentration was prepared in the range of 1-10 μg/ml and the linear regression analysis data showed good linear relationship with correlation coefficient value 0.9937. The precision of the method was studied as an intra- day, inter-day variations with value less than 2 % RSD. The limit of detection and limit of quantitation were found to be 0.577 and 1.248 μg/ml, respectively. Recoveries were found to be in the range of 100.815 to 101.744 % and % RSD was less than 2 %. This proposed UV spectroscopic method is simple and suitable for routine analysis.
Keywords: Keywords: Agomelatine, Validation, UV Spectrophotometric method
Cancer Risk Assessment of Patients Undergoing Computed Tomography Examination at the Korle-Bu Teaching Hospital
Authors: Sackey T. A. , Schandorf C. , Fletcher J. J. , Mensah Y. B. , Shirazu I. , Akyea-Larbi K. O. , Tiburu E. K. , Odonkor S. T. 
Published: February 2021

The aim of this study is to estimate the effective dose and assess the lifetime attributable risk of cancer incidence of patients undergoing computed tomography scan at the Korle-Bu Teaching Hospital in the Greater Accra Region of Ghana. Data on Volume CT Dose Index ( ) and Dose Length Product ( ) displayed on the scanner control console was recorded after confirmation of the results by performing independent checks on a phantom. The effective doses were estimated using the displayed and the anatomic region specific conversion factors ( ). The average effective dose for the head, abdomen, chest, neck, and pelvis were 3.63± 2.39mSv, 15.37±8.49 mSv, 12.72 ± 13.97 mSv, 4.04 ± 1.47 mSv and 15.8 ± 3.59 mSv respectively. Effective doses for the head and neck were within the typical range of (1-10mSv) for CT examinations whilst abdomen, chest and pelvis were above 10mSv. The average life attributable risk of cancer incidence for each region of examination were determined from the effective dose, sex and age using the model proposed in BEIR VII Report . The average cancer risk incidence for head, neck, chest, abdomen and pelvis examinations were low in the range 1 in 10,000 to 1 in 1,000. There were wide variations in the effective dose values obtained for the same region under examination. This trend calls for the optimization of CT examination protocols to be established to ensure that patient doses are as low as reasonably achievable, economic and social factors being taken into account especially for chest examinations.
2008 United States Animal Health Report
Authors:   United States. Animal and Plant Health Inspection Service. Veterinary Services. Centers for Epidemiology and Animal Health
Published: February 2021

This publication highlights APHIS Veterinary Services’ (VS) programs, events, and initiatives
aimed at maintaining healthy livestock, poultry, and aquaculture populations. In addition, the report reviews key epidemiological developments of 2008 and provides an overview of our animal health surveillance activities, as well as our emergency planning, preparedness, and monitoring efforts. This report also include an informative summary of the U.S. livestock, poultry, and aquaculture industries.
Prevalence of Transfusion Transmissible Infections In Blood Donors
Authors: Hoque Md Monirul , Saha Debashish , Khan Arif Ahmed , Tarek Monwar , Shourov Md Mehedhi Hasan 
Published: February 2021

Background: Blood transfusion is a significant life-saving intervention in the present era of patient management system. As the blood and blood products are a potential source of infection and the necessity of transfusion is increasing day by day, transfusion transmissible infections (TTIs) have become a major threat to ensure safe transfusion.
Objectives: The aim of this study was to assess the prevalence of some common and serious TTIs among blood donors as well as evaluate the pattern of seroprevalence in accordance with few other characteristics.
Methods: It was a cross sectional study which was conducted at the Department of Transfusion Medicine of Armed Forces Institute of Pathology (AFIP), Dhaka Cantonment from January 2015 to June 2017. Donors were selected very carefully according to criteria of National Guidelines of Bangladesh Government and by using a detailed questionnaire. They were screened properly for HBV, HCV, HIV, Malaria and Syphilis. All positive cases were confirmed again by using more sensitive and specific tests. We analyzed the data as percentage and comparison.
Results: A total of 32,625 donors were screened. Among them 28,775 were male and 3850 female. Total 135 were found reactive in the screening assays and among them no one was reactive in more than one assays. The prevalence of HBV and HCV in our study population was 0.38% and 0.03% respectively. It was found that percentage of HBV and HCV seropositivity was more among civilian donors. There was no positive case of Malaria, Syphilis and HIV. The number of seropositive cases were found to be decreased gradually in consecutive years. The study also revealed that both HBsAg and Anti-HCV positive cases were more prevalent amongyoung donors.
Conclusion: Our study revealed that a significant number of donors were positive for TTIs who might be a potential source of transfusion related infections. It justifies the necessity of stringent screening of blood donors to prevent the transfusion transmissible infections.
Bangladesh J Med Microbiol 2018; 12 (1): 20-23
PENGORGANISASIAN PELATIHAN OLEH KELOMPOK PENYANYI JALANAN (KPJ) KOTA BENGKULU
Authors: Kendey Kendey , Rizkan Rizkan , Gusti Ririn 
Published: February 2021

This research is aimed to know organizing training by Kelompok Penyanyi Jalanan (KPJ) Bengkulu City. The subjects of this research are four people, that is Andi as chairman of the KPJ Bengkulu City, Nita as a member of the KPJ Bengkulu City, Herman and Heri as a street child who was fostered by KPJ Bengkulu City. The method used in this research is qualitative method. The technique of collecting data used interview, observation and documentation. The data analysis techniques used data reduction, data presentation and conclusion retractation. The validity check used triangulation technique which starts from the triangulation of subject, triangulation of time and triangulation of technic. From research result, Organizing carried out by the Kelompok Penyanyi Jalanan (KPJ) Bengkulu City has been carried out. This can be seen by the organizational structure that has been compiled, which is then for each individual involved in it charged with duties and responsibilities in accordance with positions they have agreed upon previously. Keywords: , Organizing, Training, Groups,
PERAN TUTOR DALAM PELAKSANAAN METODE QIRO’ATI DI TPQ PAUDIT AL HASANAH
Authors: Angga Ari , Jasma Suardi , Gusti Ririn 
Published: February 2021

Learning the Qur'an with the Qiro'ati method is the system and how to read it smoothly, quickly, precisely, correctly, and in tartil without having to be spelled. Then the implementation model is to use props for classical implementation which contains material that is in the pages of the volume book Qiro'ati. The instructor must conduct Qiro'ati education and training so as to obtain an official diploma that can be used to teach the Qiro’ati method. Then the purpose of this research is to find out what methods are used, how the learning process is, and to find out the supporting and inhibiting factors. This research uses descriptive qualitative research methods. The research was conducted at the Al-Qur'anah Education Park PAUDIT Al Hasanah Pagar Dewa Bengkulu City on March 5 to April 5, 2019. The subjects of the study were the head and coordinator of the TPQ itself and the TPQ PAUDIT teacher Al Hasanah Pagar Dewa Bengkulu City. Keywords: Role of Tutors (Ustad / Ustadzah), Al Qur'an Learning, Qiro'ati Method
Laserterapia de baixa intensidade e seus efeitos sobre a dor, edema, trismo e parestesia: uma revisão integrativa da literatura
Authors: Olkoski Louise Eduarda , Bonai Nicolly , Pavelski Mateus Diego , Magro Filho Osvaldo , Luciano Aline Alves , Frigo Lucio , Barbieri Tharzon , Pavelski Maicon Douglas 
Published: February 2021

O interesse pelo uso da laserterapia de baixa intensidade tem surgido fortemente dentre os clínicos e estudiosos, a fim de compreender o potencial das interações da luz laser, e em particular, para bioestimular os processos de regeneração dos tecidos, controlar o processo inflamatório e a dor. O objetivo do presente trabalho é realizar uma revisão integrativa a fim de discutir a eficácia da laserterapia de baixa intensidade na prática odontológica. Para tal, utilizamos artigos científicos oriundos das bases de dados Scielo e Pubmed. Foram selecionados 19 artigos, os quais se enquadram nos seguintes critérios de inclusão: publicações dos últimos 10 anos, artigos que avaliem a efetividade na melhora da dor, edema, trismo, parestesia e estudos “in vitro” relacionados a aplicabilidade da laserterapia. Não foram considerados artigos com mais de 10 anos e estudos que não envolvam aplicação laserterapia de baixa intensidade. Os resultados dessa revisão integrativa sugerem novos ensaios clínicos randomizados para comprovar sua efetividade na prática clínica. Portanto, de acordo com a literatura consultada, a laserterapia de baixa intensidade se mostrou eficaz em diferentes aplicações e em outros quesitos, como na regeneração tecidual e no controle de processos inflamatórios. Porém, é necessário realizar novos estudos, pois pesquisas específicas a fim de avaliar efetividade da laserterapia no dor, edema, trismo e parestesia, são escassas e carecem de protocolos específicos para seu uso.
Diagnósticos de Enfermagem identificados entre usuários do Centro de Atenção Psicossocial Álcool e Outras Drogas do Município de Caucaia-CE
Authors: Dias Guanacy  Nonato , Sousa Albertina Antonielly Sydney de , Brasil Eysler Gonçalves Maia , Silva Sarah Lima Verde da 
Published: February 2021

Objetivo: identificar os principais Diagnósticos de Enfermagem entre os usuários de um Centro de Atenção Psicossocial aos Usuários de Álcool e Outras Drogas do Município de Caucaia-CE. Metodologia: estudo exploratório-descritivo, documental, quantitativo realizado no CAPS AD de Caucaia-CE. Dentre os 1020 prontuários ativos, após o cálculo amostral, elegeram-se 200 prontuários para análise. Os dados foram coletados entre dezembro de 2019 e abril de 2020, por meio de instrumento previamente elaborado, analisados por estatística descritiva simples e com base na NANDA-I (2018-2020) para a identificação dos principais Diagnósticos de Enfermagem; e discutidos com base na literatura pertinente. Resultados: O perfil dos usuários registrados era majoritariamente masculino, de adultos jovens, solteiros, com ensino fundamental incompleto, desempenhando algum tipo de ocupação, sendo o álcool a substância de preferência. Foram identificados 37 diagnósticos de Enfermagem com predominância dos com foco no problema, seguido dos de promoção da saúde. Com relação à análise dos diagnósticos de risco e com foco no problema, emergiram três subcategorias: 1) Problemas de enfrentamento e na autopercepção; 2) Problemas autodirigidos; e 3) Problemas biológicos, físicos, psicológicos e sociais. O abuso de substância despontou como elemento relacionado ou de risco para grande parte desses enunciados. Conclusão: Tendo em vista a complexidade que envolve o cuidado de Enfermagem no âmbito da Saúde Mental, aponta-se que o levantamento dos Diagnósticos de Enfermagem nesse cenário é uma ferramenta primordial para entender os indivíduos em suas singularidades e delinear intervenções alinhadas às suas necessidades de cuidado.
Pre-habilitation Before Vestibular Schwannoma Surgery—Impact of Intratympanal Gentamicin Application on the Vestibulo-Ocular Reflex
Authors: Tarnutzer Alexander A. , Bockisch Christopher J. , Buffone Elena , Huber Alexander M. , Wettstein Vincent G. , Weber Konrad P. 
Published: February 2021

Background: Patients with vestibular schwannoma that show residual peripheral-vestibular function before surgery may experience sudden and substantial vestibular loss of function after surgical resection. To alleviate the sudden loss of peripheral-vestibular function after vestibular-schwannoma (VS) resection, pre-surgical intratympanic gentamicin application was proposed.Objective: We hypothesized that this approach allows for a controlled reduction of peripheral-vestibular function before surgery but that resulting peripheral-vestibular deficits may be canal-specific with anterior-canal sparing as observed previously in systemic gentamicin application.Methods: Thirty-four patients (age-range = 27–70 y) with unilateral VS (size = 2–50 mm) were included in this retrospective single-center trial. The angular vestibulo-ocular reflex (aVOR) was quantified before and after (29.7 ± 18.7 d, mean ± 1SD) a single or two sequential intratympanic gentamicin applications by use of video-head-impulse testing. Both aVOR gains, cumulative saccadic amplitudes, and overall aVOR function were retrieved. Statistical analysis was done using a generalized linear model.Results: At baseline, loss of function of the horizontal (20/34) and posterior (21/34) canal was significantly (p &lt; 0.001) more frequent than that of the anterior canal (5/34). After gentamicin application, loss of function of the horizontal (32/34) or posterior (31/34) canal remained significantly (p ≤ 0.003) more frequent than that of the anterior canal (18/34). For all ipsilesional canals, significant aVOR-gain reductions and cumulative-saccadic-amplitude increases were noted after gentamicin. For the horizontal canal, loss of function was significantly larger (increase in cumulative-saccadic-amplitude: 1.6 ± 2.0 vs. 0.8 ± 1.2, p = 0.007) or showed a trend to larger changes (decrease in aVOR-gain: 0.24 ± 0.22 vs. 0.13 ± 0.29, p = 0.069) than for the anterior canal.Conclusions: Intratympanic gentamicin application resulted in a substantial reduction in peripheral-vestibular function in all three ipsilesional canals. Relative sparing of anterior-canal function noted at baseline was preserved after gentamicin treatment. Thus, pre-surgical intratympanic gentamicin is a suitable preparatory procedure for reducing the drop in peripheral-vestibular function after VS-resection. The reasons for relative sparing of the anterior canal remain unclear.
Application of developmental games based on kinesthetic perception to improve proprioceptive sensitivity, intelligence and cooperation in primary school children
Authors: Syahputri Aulia Maris , Sukoco Pamuji Sukoco 
Published: February 2021

Aim: to produce a game learning model based on kinesthetic perception to improve kinesthetic perception, play intelligence, and collaboration among elementary school children. Material and methods. The game learning model based on kinesthetic perception is adapted to the growth and development aspects of students which is packaged through the processing of limbs that is focused on the psychomotor domain consisting of a series of basic locomotor movements, manipulative, non-manipulative, cognitive play intelligence, and effective cooperation. The method used is research and development, namely descriptive, evaluative and experimental methods. This research method is used to produce a product, namely a game learning model based on the kinesthetic perception of children aged 7-8 years which is equivalent to lower grade elementary school students. Development procedures: (1) collecting research results and information, (2) analyzing the product to be developed, (3) developing the initial product, (4) conducting expert validation, (5) conducting small-scale trials and revisions, (6) conducting large-scale trials and revisions, (7) making final products, and (8) conducting effectiveness tests. The subjects of this study were grade 1 elementary school students. The data analysis techniques used were quantitative and qualitative descriptive analysis. The final product effectiveness test used one group pretest-posttest design experiment. Results. The results of this study are in the form of a kinesthetic perception-based game learning model to improve kinesthetic perception, playing intelligence, primary school children's collaboration which contains four games, namely (1) Target Shooting Games, (2) Train Car Games, (3) Flag Games, and ( 4) Rakartugu Games. From the results of the assessment of experts and practitioners, the game learning model based on kinesthetic perception has a validity of 0.963. Conclusions. Kinesthetic perception based game learning model is effective for developing kinesthetic perception limb processing skills, playing intelligence and cooperation.
Features of individual cognitive style of qualified badminton players
Authors: Xiang Qian Xu , Korobeynikov G.V. , Mishchuk D.M. , Korobeynikova L.G. 
Published: February 2021

Aim: to determine of peculiarities of personal cognitive styles in qualified badminton players.
Material and methods. The studies were carried out using the hardware-software computer complex "Multipsychometer-05". The modified Stroop test was selected. The indicators of the test "Field dependence" were determined: field independence, left hemispheric dominance, functional asymmetry, and the effectiveness of the test. The obtained results of the study were analyzed for the entire sample of badminton players, as well as separately for men and women.
Results. According to the results of scientific research on the field dependence of qualified badminton players, it was found that all athletes in our sample demonstrate a slight bias towards field dependence; dominated by right hemisphere dominance; in functional asymmetry and efficiency, qualified badminton players demonstrate an average level. The analysis of test indicators, taking into account gender dimorphism, showed that among men 72% demonstrate a predominance of right hemispheric dominance of varying degrees, 28% have left hemispheric dominance. As for women, 54% demonstrate a predominance of right hemispheric dominance of varying degrees, and 37% demonstrate left hemispheric dominance of varying degrees.
Conclusions. Men show a tendency towards better test performance and have more pronounced functional asymmetry. The cognitive style of skilled badminton players determines the strategy of selection and processing of information, problem solving, learning and other types of cognitive activities. Because human cognitive-activity styles are genetically determined and demonstrate a pronounced stability of cognitive-stylistic characteristics in ontogenesis, they can be used as prognostic and diagnostic criteria.
Fatty acid profile, antioxidant and antibacterial effect of the ethyl acatate extract of cleistopholis patens
Authors: A.O Daniels , Temikotan Taye 
Published: February 2021

Cleistopholis patens is a tropical plant that is used in the treatment of many bacterial and fungal infections. In this study, the antibacterial action against some human pathogens and the fatty acid profile of the plant were investigated. The plant was found to be active against Salmonella typhi Streptococcus pyogenes, Staphylococcus aureus while Shigella dysenteriae was resistant. The comparative antibiotic test revealed that only Staphylococcus aureus was sensitive to chloramphenicol and gentamycin. The purified extract showed lesser activity than the crude extract. Phytochemical components include; glycosides, steroids, Phenol, tanins and saponins. Anticonstituents include tanin (2.32mg/g), phenol (2.50 mg/g), phytate (15.65 mg/g), oxalate (6.57 mg/g), saponin (9.71 mg/g) and flavonoids (6.49 mg/g). The GCMS profile of the ethyl acetate extract of the plant revealed 23 fatty acid including 9-Hexadecanoic acid, (25.11%), 6 octadecanoic acid (21.98%), n Hexadecanoic (4.62%), Cyclopentaneundecanoic acid, methyl ester (2.05%). Heptacosanoic acid, methyl ester (2.05%), Decanoic acid, methyl ester (1.74%), Oleic acid (4.38%), 16-Octadecenoic acid, methyl ester (3.55%) amongst others.
Budaya Iyakyaker dalam Peningkatan Nilai-Nilai Sosial di Distrik Sorong Kota
Authors: Herningsih Herningsih 
Published: February 2021

Abstract
This study aims to describe and analyze cultural values in increasing social values in the Sorong Kota district with the focus of the study covering: culture, customs and values on the character of the Biak Tribe in Sorong Kota District. This study uses a qualitative approach with data collection techniques using interviews, observation and documentation and data analysis techniques, namely data reduction, data presenter, data presenter and research conclusions using the results of the study show that the social values that occur are not only a benchmark in ethnic culture/customs. breed but has a major role to tie a sibling association and a customary system, the customary system includes regional languages, regional languages are ancestral cultures that are beginning to be eroded by time, regional language culture is the body of ancestral customs so it must be preserved, because culture (language area) is a systematic one that describes the existence of a person in the ethnicity/origin of a person.

Abstrak
Penelitian ini bertujuan untuk mendeskripsikan dan menganalisis tentang budaya iyakyaker dalam peningkatan nilai sosial di distrik sorong kota dengan fokus kajian mencakup: budaya, adat dan Nilai terhadap karakter masyarakat Suku Biak di Distrik Sorong Kota. Penelitian ini menggunakan pendekatan kualitatif dengan Tehnik pengumpulan data mengunakan diantaranya Wawancara, observasi dan dokumentasi dan Teknik Analisis Data yaitu reduksi data, penyaji data, penyaji data dan kesimpulan penelitian mengunakan Hasil penelitian menunjukan bahwa nilai sosial yang terjadi tidak hanya sebagai patokan dalam budaya/adat suku biak akan tetapi memiliki peran utama untuk mengikat suatu perkumpulau saudara dan sistem adat, sistem adat tersebut diantaranya bahasa daerah, Bahasa daerah merupakan budaya leluhur yang mulai terkikis oleh jaman, Budaya bahasa daerah merupakan raga dari adat leluhur sehingga harus tetap dilestarikan, karena budaya (bahasa daerah) merupakan salah satu sistematis yang mengambarkan tentang keberdaan seseorang dalam suku/asal-usul seseorang itu berasal.
Kata Kunci: Budaya, Adat, Nilai Sosial
Presentación
Authors: Editorial Comité 
Published: February 2021

Un nuevo volumen actualiza nuestro compromiso de seguir convocando a los docentes y estudiantes al trabajo intelectual, como una actividad prioritaria que fundamenta la razón de ser de la institución universitaria, cuya finalidad es permitir que la investigación, la creación, el proceso cultural y la práctica docente se integren y se potencien de una manera efectiva. Por ello desde EDUCA-UMCH se pretende entablar un espacio para el logro de esas metas y su difusión oportuna.

COMITÉ EDITORIAL
Formación general, necesidad del currículo universitario
Authors: Peñaloza Ramella Walter 
Published: February 2021

En el presente texto vamos a ocuparnos de la formación General en los currícula universitarios. Más acontece que la noción de Formación General se halla oscurecida por una serie de ideas y definiciones poco afortunadas que han generado confusión entre los profesores universitarios. Conviene por ello deslindar conceptos y separar lo que es Formación General y distinguirla de otras estructuras curriculares con las cuales a veces se la mezcla indebidamente.