bluuebunny/crossref_metadata_2025_split huggingface dataset:
La Recherche et l’Innovation en France
Authors: Nemessany Violette 
Published: October 2021

FutuRIS s’est intéressé, en 2014, aux modes d’approche des entreprises par les établissements publics de recherche et à leur manière de nouer des relations avec elles. Cette année, ce chapitre concentre son attention, à l’inverse, sur les entreprises. Sur la base d’une série d’entretiens réalisés avec des représentants de grands groupes, ETI et PME, il met tout d’abord en perspective l’effort de RD privé en France et le volume de recherche contractuelle. Sont ensuite passés au crible les enjeux et les attentes des entreprises, les moyens mis en œuvre pour identifier les résultats de la recherche publique, les difficultés rencontrées et les conditions de la réussite d’un partenariat, dans lesquelles la confiance joue un rôle essentiel. Le chapitre montre que le partenariat avec la recherche publique est devenu une nécessité pour les entreprises qui sont à la recherche de nouvelles compétences et de moyens complémentaires pour innover et rester compétitives dans un environnement concurrentiel. Il peut prendre des formes variées selon les besoins et les enjeux auxquels sont confrontées les différentes catégories d’entreprises. Les modes d’approche diffèrent également : si les grands groupes, les start-up technologiques et, dans une moindre mesure, les ETI initient facilement le contact, les PME, en revanche, rencontrent davantage de difficultés compte tenu de leurs capacités limitées en matière de RD et de l’insuffisance de leurs ressources tant financières qu’humaines. Parmi celles qui s’engagent dans des programmes de recherche bilatéraux, il apparaît que c’est le dirigeant de la PME qui est, le plus souvent, à l’origine de l’initiative. Mais, accaparé par la gestion quotidienne de son entreprise, il peine à tout mener de front. C’est pourquoi, les PME attendent un accompagnement personnalisé pour les orienter vers le bon partenaire, instaurer le dialogue et les guider tout au long du projet. Le renforcement des services de valorisation et le recrutement de nouveaux profils tels que les « business developers » et les commerciaux au sein d’un nombre, encore limité, d’établissements publics de recherche témoignent de la prise en compte de cette attente. Enfin, six pistes de progrès, susceptibles d’améliorer le cadre d’ensemble dans lequel s’inscrivent les partenariats public-privé, ont été dégagées. Destinées aux entreprises, établissements publics de recherche et pouvoirs publics, elles se placent dans une perspective d’accompagnement des évolutions en cours. En 2016, FutuRIS publiera un rapport qui combinera les deux études menées au cours des deux dernières années.
Oral Health Complications in Type 2 Diabetes
Authors: Sanyal Palash Kumar , Srirammohan Pramod , Chaudhuri Sirshendu 
Published: October 2021

Background:
Oral health evaluation is one aspect of diabetes care, that is usually not practised in majority of health care settings in India.

Aims:
To-identify the various complications related to oral health among Type 2 diabetics in a secondary care hospital in South India; and to identify the various determinants associated with it.

Methods:
In this cross-sectional study among the employees state insurance beneficiaries, we conveniently sampled the Type 2 diabetes patients attending the outpatient department for routine diabetic care and evaluated for some preidentified oral health conditions.

Results:
We recruited 124 participants, 76 (61.3%) males. The average duration of diabetes was 6.5 years (inter-quartile range-3–7 years). Gingivitis (n = 97, 78.2%) was the most common complication. Other important complications include-loss of functionality (n = 88, 71%), calculous (n = 87, 70.2%), and gingival recession (n = 56, 45.2%). In multivariate logistics regression modeling, young diabetics (adjusted odds ratio [AOR] −6.2; 95% confidence interval [CI] −2.2,17.6) and male populations (AOR − 2.6; 95% CI − 1.1, 6.0) were at higher risk of developing multiple complications.

Conclusions:
Diabetic population frequently suffers with oral complications. Health care professionals can include the importance of dental health care in the routine health education session for diabetics. In addition, clinicians can recommend dental evaluation to the diabetics apart from other clinical biochemical evaluation.
The burden of diabetic kidney disease in Nigeria − systematic review and meta-analysis
Authors: Azeez Taoreed A. , Efuntoye Oluwafemi , Abiola Busayo I. , Adeyemo Segun P. , Adewale Boluwatife A. 
Published: October 2021

Background
Diabetic kidney disease (DKD) is a microvascular complication of diabetes mellitus. Considering that the burden of diabetes mellitus is rising in Nigeria, there is a need to ascertain the burden of one of its most common complications. The objective of the meta-analysis was to determine the pooled prevalence of DKD in Nigeria and identify its risk factors.

Patients and methods
The study is a meta-analysis and it followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Google scholar, PubMed, AJOL, SCOPUS, medRxiv, and the gray literature were systematically searched using appropriate key terms. Statistical analysis was done with MetaXL. The inverse-variance heterogeneity model was used for the meta-analysis and heterogeneity was determined using the I
2 statistic and the Cochran's Q test. Publication bias was checked with the Doi plot and LFK index.

Results
Nineteen studies met the eligibility criteria. The total sample size was 56 571. The pooled prevalence of DKD in Nigeria was 28% (95% confidence interval 3–58). The Cochran's Q was 747 (P<0.001), while the I
2 statistic was 97.6%. The Doi plot was drawn and the LFK index was 6.22. The most common risk factors for DKD were suboptimal glycemic control, hypertension, obesity, duration of diabetes, male sex, and advancing age.

Conclusion
The prevalence of DKD in Nigeria is high and greater attention should be focused on managing the risk factors so as to alleviate the burden of the disease.
The interrelation between body mass index and post-dural puncture headache in parturient women
Authors: Beyaz Serbülent Gökhan , Ergönenç Tolga , Saritaş Aykut , Şahin Fatih , Ülgen Ali Metin , Eman Ali , Doğan Burcu 
Published: October 2021

Background and Aims:Post-dural puncture headache is seen more frequently in pregnant women due to stress, dehydration, intra-abdominal pressure, and insufficient fluid replacement after delivery. Obesity protects against post-dural puncture headache in pregnant women; increased intra-abdominal fat tissue reduced cerebrospinal fluid leakage by increasing the pressure in the epidural space. Therefore, this study investigated the influence of body mass index on post-dural puncture headache in elective cesarean section patients in whom 27G spinal needles were used.Material and Methods:The study included 464 women who underwent elective cesarean section under spinal anesthesia. Dural puncture performed with a 27G Quincke spinal needle at the L3-4 or L4-5 intervertebral space and given 12.5 mg hyperbaric bupivacaine intrathecally. The patients were questioned regarding headache and low back pain 6, 12, 24, and 48 h after the procedure, and by phone calls on days 3 and 7.Results:Post-dural puncture headache developed in 38 (8.2%) patients. Of the patients who developed post-dural puncture headache, 23 (60.5%) had a body mass index <30 and 15 (39.5%) had a body mass index ≥30. Of the patients who did not develop post-dural puncture headache, 258 (60, 6%) had a body mass index <30 and 168 (39, 4%) had a body mass index ≥30. Conclusion: This prospective study found the body mass index values did not affect post-dural puncture headache in the elective cesarean section performed under spinal anesthesia.
Effect of intraabdominal hypertension on splanchnic blood flow in children with appendicular peritonitis
Authors: Perova-Sharonova Valentyna M. , Albokrinov Andrew A. , Fesenko Ulbolhan A. , Gutor Taras G. 
Published: October 2021

Background and Aims:Intraabdominal hypertension (IAH) is poorly diagnosed condition that cause splanchnic hypoperfusion and abdominal organs ischemia and can lead to multiple organ failure. There are no scientific data regarding effect of intraabdominal pressure (IAP) on splanchnic circulation in children.Material and Methods:Ninety-four children after surgery for appendicular peritonitis were enrolled in the study. After IAP measurement children were included in one of two groups according IAP levels: “without IAH” (n= 51) and “with IAH” (n= 43). Superior mesenteric artery (SMA) and portal vein (PV) blood flows (BFSMA, BFPV, mL/min) were measured, and SMA and PV blood flow indexes (BFISMA, BFIPV, ml/min*m2) and abdominal perfusion pressure (APP) were calculated in both groups.Results:Median BFISMAand BFIPVin group “with IAH” were lower by 54.38% (P, 0.01) and 63.11% (P< 0.01) respectively compared to group “without IAH”. There were strong significant negative correlation between IAP and BFISMA(rs= –0.66;P, 0.0001), weak significant negative correlation between IAP and BFIPV(rs= –0.36;P= 0.0001) in group “with IAH” and weak significant negative correlation between IAP and BFISMA(rs= –0.30;P= 0.0047) in group “without IAH”. There were no statistically significant correlations between IAP and BFIPVin group “without IAH”, between BFISMAand APP in both groups and between BFIPVand APP in both groups.Conclusion:Elevated IAP significantly reduces splanchnic blood flow in children with appendicular peritonitis. BFISMAand BFIPVnegatively correlate with IAP in these patients. There is no correlation between BFISMA/BFIPVand APP in children with IAH due to appendicular peritonitis.
Influence of gender on postoperative pain in percutaneous nephrolithotomy: A prospective observational study
Authors: Jonnavithula Nirmala , Garg Heena , Allenki Prashanthi , Aavula Kireeti 
Published: October 2021

Background and Aims:Percutaneous nephrolithotomy (PCNL) is the procedure of choice for managing large renal calculi. Although minimally invasive, it is associated with pain due to dilatation of renal capsule, parenchymal tract, and nephrostomy tube placement. Gender differences in pain perception and analgesic requirement have not been studied in PCNL surgeries. This study was done to evaluate the influence of gender on pain.Material and Methods:It was a prospective observational study including 60 ASA physical status I and II patients. The number of males and females were 29 and 31, respectively. Analgesic requirement and postoperative pain score were assessed by visual and dynamic visual analog scales (VAS, DVAS) score fourth hourly for first 24 h. Rescue analgesia was IV paracetamol 1 g when pain score exceeded four. VAS scores were assessed using Mann–Whitney test. Rescue analgesia was calculated as frequency and proportions. APvalue of <0.05 was considered statistically significant.Results:The mean pain score values (VASP= 0.361; DVASP= 0.332) and postoperative fentanyl (P= 0.703) did not show a statistically significant difference in males and females. The requirement of rescue paracetamol was higher in females with 30 out of 31 females demanding a rescue analgesic in comparison to 15 out of 29 male patients (P= 0.001).Conclusion:No significant difference was observed in postoperative pain among males and females in patients undergoing PCNL surgery. The analgesic requirement, however, was found to be more in females than in males.
A comparative evaluation of Airtraq and Hansraj Video laryngoscopes in patients undergoing tracheal intubation with cervical spine immobilization - A randomized prospective study
Authors: Varshney Poojangi , Ahmed Syed M. , Siddiqui Obaid A. , Nadeem Abu , PM Ajmal 
Published: October 2021

Background and Aims:Airway management is a key concern in trauma patients with cervical spine fracture. Application of manual inline axial stabilization (MIAS) has become the standard of care in these patients. Indirect laryngoscopy only requires alignment of the pharyngeal and laryngeal axis. Hence the primary objective of the study was to compare two indirect laryngoscopes, Airtraq (with adaptor) and Hansraj Video laryngoscopes based on its Intubation Difficulty Score.Material and Methods:Sixty anesthetized patients were divided into two groups using computer-based randomization, and tracheal intubation was performed using either Airtraq or Hansraj Videolaryngoscope with cervical spine immobilization.Results:Both Airtraq and Hansraj groups were comparable in terms of percentage of glottic opening (POGO) scoring (92 ± 9.88% vs. 89.3 ± 10.4%.) and duration of intubation attempt (14.9 ± 4.36 sec vs. 16.97 ± 3.64 sec). Intubation difficulty scale (IDS) score was significantly shorter with Airtraq (1 ± 0.58 vs. 1.8 ± 0.805;P< 0.0001). The mean duration of time taken for laryngoscopy in Airtraq (12.9 ± 2.07 s vs. 19.06 ± 3.83 s;P< 0.0001)) was significantly shorter and also the duration of time taken to secure airway in Airtraq VL was significantly shorter (29.47 ± 4.75 s vs. 36.03 ± 5.80 sec;P< 0.0001). The heart rate and MABP changes were modest in both groups, but was significantly more in Hansraj VL as compared to Airtraq VL, post-intubation.Conclusion:Both Airtraq and Hansraj videolaryngoscope can be used as first-hand device in the scenario of cervical spine stabilization. Airtraq videolaryngoscope is better than Hansraj videolaryngoscope due to shorter IDS and lessor hemodynamic changes.
A retrospective study comparing analgesic efficacy of ultrasound-guided serratus anterior plane block versus intravenous fentanyl infusion in patients with multiple rib fractures
Authors: Diwan Sandeep , Nair Abhijit 
Published: October 2021

Background and Aims:Inadequately managed pain due to multiple rib fractures (MRFs) can lead to atelectasis, pneumonia, prolonged ICU stay thereby leads to significant morbidity, morbidity and cost of treatment. Opioids, non-steroidal anti-inflammatory drugs and regional anaesthesia techniques like thoracic epidural or paravertebral blocks, intercostal nerve blocks are used to manage pain. Serratus anterior plane block (SAPB) is an ultrasound (US) guided interfascial plane block which has been used in managing pain due to MRFs. In this retrospective study, we compared analgesic efficacy and 24 hr fentanyl consumption in patients with MRFs who were managed with continuous SAPB versus patients who were managed with fentanyl infusion alone.Material and Methods:After Institutional Ethics Committee approval, we retrospectively collected data of 72 patients (38 in SAPB group and 34 in fentanyl group). Demographic data, VAS scores and 24 hrs fentanyl consumption was analysed in both groups.Results:There were statistically significant lower pain scores in patients of SAPB group when compared to that of fentanyl group (p=0.001) and in 24 hrs fentanyl consumption in patients who received continuous SAPB versus that in fentanyl group(p=0.001). No complications were observed in patients who received US guided SAPB.Conclusion:US guided SAPB is an opioid sparing, effective interfascial plane block which is safe and should be considered early in all patients who sustain MRFs. Continuous SAPB by placing a catheter can provide pain relief for longer duration, facilitate early mobilization, physiotherapy and early ICU discharge.
Determination of the efficacy of ultrasound-guided bilateral transversus abdominis plane (US-TAP) block in laparoscopic total extraperitoneal (TEP) repair of unilateral hernia surgeries: A randomized controlled trial
Authors: Sivapurapu Vijayalakshmi , Gopal Sri Vengadesh , Solomon Ashley 
Published: October 2021

Background and Aims:Bilateral ultrasound-guided transversus abdominis plane (US-TAP) block has been successfully used to provide analgesia for most lower abdominal procedures. Our aim was to determine the efficacy of US-TAP block with levobupivacaine in laparoscopic total extraperitoneal (TEP) repair of unilateral hernia surgeries under general anaesthesia (GA) as compared to no block.Material and Methods:It is prospective randomised controlled study done in a tertiary care centre in South-East Asia. After obtaining Institute Ethics Committee approval and consent, 60 patients of ASA I-II aged between 18 to 80 years were randomized into two groups. After receiving GA, Group TAP - received bilateral US-TAP block with levobupivacaine 0.25% 0.3ml kg-1on either side whereas, the control group did not receive any block. The time taken to first request for rescue analgesic (T Rescue) by the patient and the Numeric Rating Scale (NRS) at that time point were noted and tramadol 50mg i.v. was administered, followed by 50mg i.m. PRN for 24 h from the time of extubation. The 24 h analgesic requirement was noted in mg kg-1.Results:Results were analysed using SPSS 16 andP < 0.05was considered significant. T Rescue was significantly longer in the TAP Group(P = 0.02)with lower NRS at time points 24 h(P = 0.02)and 12 h(P = 0.004). Postoperative nausea and vomiting were significantly less in TAP Group(P < 0.001).Conclusion:Bilateral US-TAP block provided better analgesia and side effect profile as compared to no block when administered in laparoscopic TEP repair of hernia surgeries.
Fentanyl versus nalbuphine for intubating conditions during awake fiberoptic bronchoscopy: A randomized double-blind comparative study
Authors: Chaudhary Sujata , Chaudhary Sachin , Kumar Mahendra , Salhotra Rashmi 
Published: October 2021

Background and Aims:Patient cooperation, sedation, anxiolysis, and topicalization are important prerequisites for the successful and safe conduct of awake intubation. Because of the pharmacological properties, opioids can facilitate this process. Fentanyl is an opioid agonist and nalbuphine is an agonist-antagonist. This study aims to compare these two opioids for their effect on sedation and intubating conditions during awake fiberoptic intubation.Material and Methods:This randomized double-blind controlled study was conducted on 62 ASA I/II patients of either sex between the age of 20 and 60 years, weight between 40 and 80 kg, with MP class I/II airways requiring general anesthesia with endotracheal intubation. All patients received standard airway topicalization and nebulization. Patients were randomly allocated to one of the two groups according to a computer-generated random number table. Group F (n= 31) received fentanyl 2 µg/kg i.v. and group N (n= 31) received nalbuphine 0.2 mg/kg i.v. over 10 min before intubation. Fiberoptic intubation was attempted and lignocaine spray and propofol boluses were administered as and when required. Hemodynamic responses and intubating conditions were recorded. Repeated measure ANOVA, McNemar test, and Chi-square test or Fischer's exact test were used for data analysis. AP< 0.05 was considered significant.Results:Cough score (P= 0.458), post-intubation score (P= 1.000), and sedation score (P= 1.000) were comparable among the two groups. Hemodynamic responses and propofol and lignocaine requirements were also comparable.Conclusion:Both fentanyl and nalbuphine provide comparable intubating conditions when used before awake fiberoptic intubation with minimal adverse effects on hemodynamic profile.
Beta-human chorionic gonadotropin levels as early predictor for progression to Gestational Trophoblastic Neoplasia after molar pregnancy evacuation at a Philippine tertiary hospital
Authors: Galingan May Delight G. , Cagayan Ma. Stephanie Fay S. 
Published: October 2021

OBJECTIVE:
This study aimed to determine if the beta-human chorionic gonadotropin (hCG) levels during the first 5 weeks after a molar evacuation predict progression to gestational trophoblastic neoplasia (GTN).

MATERIALS AND METHODS:
This was a retrospective cohort study of complete mole cases managed at a Philippine tertiary hospital from January 2009 to December 2018. Extracted data were analyzed using applicable statistical tools. The level of significance was set at a P< 0.05 using two-tailed comparisons.

RESULTS:
One hundred and fifty-five complete patient records were available for review. Disease progression in 15.48% of cases while regression in 84.52% were noted. Uterine size was larger in those who eventually had postmolar GTN (t: −3.12, df: 32.64, P: 0.01). Analysis of the receiver operating characteristic curve showed that optimum cut-off levels for predicting GTN at 1, 3, and 5 weeks after evacuation were 4,152 mIU/ml (sensitivity: 50%, specificity: 94.7%, area under the curve [AUC]: 0.75), 804 mIU/ml (sensitivity: 62.5, specificity: 96.9%, AUC: 0.94), and 541 mIU/ml (70.8%, specificity: 97.7%, AUC: 0.96), respectively.

CONCLUSION:
The level of hCG within the first 5 weeks after molar pregnancy evacuation is predictive of progression to GTN.
A cone-beam computed tomography evaluation of bone density for insertion of pterygoid implants in dentulous and edentulous patients
Authors: Sahoo Pradyumna Kumar , Awinashe Vaibhav , Bali Yashika , Gupta Nitika , Parihar Anuj Singh , Jagadeesh Kyatsandra Narasimhaiah , Babaji Prashant 
Published: October 2021

Objectives:
The bone quantity and quality determine the prosthetic success outcome. This research was performed to evaluate the bone density for insertion of pterygoid implants in edentulous and dentulous participants with cone-beam computed tomography (CBCT).

Materials and Methods:
CBCT evaluation was done for 66 dentate and edentulous patients for pterygoid implants at the pterygomaxillary region. The calculation of joint width, height, and volume of bone was done. Density of the bone was evaluated at the superior and inferior aspects of the pterygomaxillary column.

Results:
It was observed that average pterygomaxillary joint height for dentulous (dentate) was −12.7 ± 7.2 mm, edentulous −12.4 ± 7.1 mm, the average pterygomaxillary joint width for dentulous was 8.15 ± 7.3 mm, and 8.13 ± 6.2 mm for edentulous. The average pterygomaxillary joint volume in dentulous participants was 279.4 ± 189.2 mm3 and for edentulous was 254.5 ± 176.4 mm3. There was expressively greater density of the bone in dentulous participants over edentulous participants (P < 0.05).

Conclusion:
There was better bone density found in dentate participants in comparison to edentulous participants. CBCT is a recent investigative device which measures pterygoid area efficiently. Pterygoid implants may be deliberated as an alternative method for resorbed (atrophic) maxilla.
Cambios en el paisaje de menorca desde 1975 hasta 2010 mediante teledetección
Authors: Ramírez-Juidías Emilio , Víquez-Urraco Francisco 
Published: October 2021

La isla de Menorca, Reserva de la Biosfera, ha originado una fuerte atracción turística a consecuencia de su gran riqueza paisajística. En este estudio, se analizaron 265 imágenes Landsat procedentes del United States Geological Service para el periodo 1975-2010, todas examinadas y clasificadas en un determinado lapso de tiempo con el fin de poder caracterizar correctamente el desarrollo territorial espacial y temporalmente. Los resultados muestran como entre 1975 y 1990 no existe desarrollo del paisaje. Entre 1990 y 2000, hay un gran aumento de la vegetación a consecuencia de la protección recibida por la Unesco. En el periodo 2000-2010, es evidente el efecto del clima en el desarrollo del paisaje.

The island of Menorca, Reserve of the Biosphere, has created a strong tourist attraction due to its rich landscape. In this research, 265 Landsat satellite images from the United States Geological Service were analyzed or the 1975 to 2010 eriod, each of which was examined and classified in a certain period of time in order to characterize right way the territorial development both spatially and temporally. The results show how between 1975 and 1990 there is virtually no landscape development. Between 1990 and 2000, there is a strong increase of vegetation as a result of the protection received by UNESCO. In the period 2000-2010, it was evident the effect of climatic factors in the landscape development.