bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social Factors and Coping Models of Women as The Violence Victims In Ponorogo District
Authors: Rokamah Ridho , Roihanah Rif'ah 
Published: April 2021

This study examines the social factors and coping models of women as victims of domestic violence after divorce. This research used the qualitative approach while the data collection techniques are included an interview, observation, and documentation. This study's conclusions are (1) social factors, from an education point of view, they consist of the lowest education, namely junior high school and the highest in college. From their social status consisting of low, medium, and high social status, and from environmental factors, it can be concluded that respondents come from various social environments. Other factors that trigger the violence occur to women such as age, economy, independence, career women, etc. (2) The coping model of women as the victims of violence in facing post-divorce stressors in Ponorogo Regency is divided into two; namely, the problem focuses coping and emotional focused coping.Penelitian ini mengkaji bagaimana faktor sosial dan model coping perempuan korban kekerasan dalam rumah tangga pasca perceraian. Pendekatan penelitian yang digunakan dalam penelitian ini adalah pendekatan kualitatif. Sedangkan teknik pengumpulan datanya meliputi wawancara, observasi dan dokumentasi. Kesimpulan dari penelitian ini adalah: 1) faktor sosial apabila dilihat dari pendidikan, mereka terdiri dari pendidikan terendah yaitu SMP dan tertinggi perguruan tinggi, dilihat dari status sosial mereka terdiri atas status sosial rendah, sedang, dan tinggi, dan jika dilihat dari faktor lingkungan, sehingga bisa disimpulkan responden berasal dari lingkungan sosial yang beragam, dan ada faktor lain yang menyebabkan kekerasan terjadi terhadap perempuan seperti masalah usia, ekonomi, kemandirian isteri, pekerjaan isteri, dan lain-lain. Dan 2) model coping perempuan korban kekerasan dalam menghadapi stressor pasca perceraian di Kabupaten Ponorogo terbagi menjadi dua yaitu; Problem Focus Coping dan Emosional Focused coping.
The Contribution of Human Rights in Thinking on Renewing The Book of Law of Criminal Events (KUHAP)
Authors: Yahyanto Yahyanto 
Published: April 2021

The fundamental principle of human rights is that all people are born free and have equality in human rights. Equality requires equal treatment; it means that anyone should be treated equally in any condition before the law. The idea of Human Rights in the Draft of the Law on Criminal Procedure Code, which will be upheld, will become a new legalized law in the future, not apart from lifting and placing a suspect, defendant, and convicted dignified position as a creature of God. Moreover, in the end, declarative human rights principles will not mean much if the stage of the rule of law does not follow them.Fundamental dari hak asasi manusia adalah ide yang meletakkan semua orang terlahir bebas dan memiliki kesetaraan dalam hak asasi manusia. Kesetaraan mensyaratkan adanya perlakuan yang setara, dimana pada situasi sama harus diperlakukan dengan sama, dimana pada situasi yang berbeda diperlakukan dengan berbeda pula. Pemikiran HAM dalam RUU KUHAP yang akan diundangkan menjadi UU kedepan, tidak terlepas mengangkat dan menempatkan seorang tersangka, terdakwa dan terpidana dalam kedudukan yang bermartabat sebagai makhluk ciptaan Tuhan. Dan pada akhirnya, prinsip-prinsip HAM yang bersifat deklaratif tidak akan banyak berarti apabila tidak diikuti dengan tahap supremasi hukum.
The Effects of Rutin Flavonoid Supplementation on Brain White Matter and Gray Matter Abnormalities in Type 2 Diabetes Mellitus Patients: A Diffusion Tensor Imaging -Based Study Protocol for a Double-Blind, Randomized Controlled Trial
Authors: Moghadam Ali Reza Eftekhari , Javid Ahmad Zare , Asl Jafar Fatahi , Moradi Leila , Rezaeyan Abolhasan , Behbahani Hossein Bavi , Bazyar Hadi 
Published: April 2021

Abstract
Background: Brain microstructural changes in white matter (WM) and gray matter (GM) of type 2 diabetes mellitus (T2DM) patients can be explained using Diffusion Tensor Imaging (DTI) method. Increased oxidative stress has been recognized the key factor in T2DM induce neural damage. Rutin flavonoid plays protective roles in several oxidative stress-mediated neurodegenerative disorders. So, the effects of rutin on WM and GM continuous changes in T2DM patients requires to be more investigated.Method: We will conduct a 3 months, double-blind, randomized controlled clinical trial to examine the effects of rutin supplementation on WM and GM changes in 26 T2DM cases. The intervention group (n=13) and the control group (n=13) will receive one tablet of 1 g rutin/day and one tablet of 1 g placebo/day after meals, respectively. Before and after the intervention, DTI will perform at 1.5 Tesla, followed by an analysis employing tract-based spatial statistics (TBSS) to explore the changes in fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (λ1), and radial diffusivity (λ23) among the rutin and placebo treated groups. A receiver operating characteristic (ROC) test will use to evaluate the performance of DTI criteria for cutting off the two T2DM groups. Discussion: We will demonstrate the diverse influences of rutin supplementation on WM and GM integrity on T2DM patients. Since, rutin may regulate neurotoxicity, oxidative stress, inflammatory reaction and nitric oxide production in nervous system; for the first time, the effects of rutin on WM and GM alterations will be evaluated by DTI in T2DM patients. Trial registration: Iran Clinical Trials Registry, registration number: IRCT20151128025274N6. Registered on 10 January 2021, https://fa.irct.ir/user/trial/53283/view
Wide-angle X-ray Scattering studies on contemporary and ancient bast fibres used in textiles – ultrastructural studies on stinging nettle
Authors: Viljanen Mira , Suomela Jenni , Svedström Kirsi 
Published: April 2021

Abstract
Stinging nettle (Urtica dioica) among other bast fibres, is a potential fibre source material for industrial and manufacturing applications. However, systematic research on the ultrastructural properties of nettle fibres is lacking. Determining the ultrastructural parameters of the bast fibres could provide also new insights into the studies of archaeological and historical fibres and their usage. In this study, modern and ancient fibre samples of stinging nettle were studied using wide-angle X-ray scattering (WAXS) and compared to other well-studied plant fibre species. From the WAXS patterns, the mean microfibril angle, average cellulose crystallite width and relative crystallinity index were determined. Besides, the suitability of the WAXS method for fibre identification purposes was studied. The culturohistorical research material consisted of fibre samples of nettle, flax and hemp acquired from White Karelian textiles collected 1894 as well as of 800–900-year-old archaeological textile fragments from Ravattula Ristimäki burial site in Kaarina, Southwest Finland. The crystallite widths for all modern fibres were of the similar size, however subtle differences in the relative crystallinity values in descending order (from flax to nettle and finally hemp) were observed. For the culturohistorical fibres, the values for average crystallite width and relative crystallinity were larger compared to the modern references of the same fibre type. In addition, individual features due to the presence of other crystalline substances (noncellulosic, minerals e.g., calcium oxalates), were detected in the scattering patterns of all modern nettles. These features could potentially be used as a tool to identify modern nettle fibres.
Retinal Morphological Alterations in Polycythemia Vera: An Optical Coherence Tomography Angiography Study
Authors: Akdogan Muberra , Dogan Mustafa , Alizade Anar , Sabaner Mehmet Cem , Gobeka Hamidu Hamisi , Yavasoglu Filiz 
Published: April 2021

Abstract
PurposeInvestigation of retinal morphological alterations in patients with polycythemia vera (PV) using optical coherence tomography angiography (OCTA).Materials and MethodsThirty PV patients (group 1) who were followed-up at Afyonkarahisar Health Sciences University Hospital, Department of Hematology, and 30 normal subjects (group 2) who applied to Ophthalmology Department for routine eye examination were enrolled in this cross-sectional, single-centered study. Following a comprehensive ophthalmological examination, all participants underwent spectral-domain OCTA examination with Angio Retina mode (6x6 mm). Data were compared between groups for statistical significance.RESULTSThe male-to-female ratio was 1:1. Mean ages were 46.97±3.20 and 47.42±2.55 years in groups 1 and 2, respectively (P: 0.350). Compared to group 2, group 1 had higher values of superficial whole, parafoveal, deep foveal, perifoveal region vascular density, foveal avascular zone perimeter, and foveal vascular density in 300 μm wide regions around foveal avascular zone values, although there were no statistically significant differences. Further, group 1 had statistically non-significantly decreased flow values and foveal avascular zone area compared to group 2. The superficial foveal vascular density was statistically significantly higher in group 1 than in group 2 (P: 0.032).CONCLUSIONFor the first time, the present study has revealed association of PV with substantial increase in the vascular density almost all around the foveal region. This suggests consideration of potential hyperviscosity impact on the vessel density during macular microcirculation assessment of patients with PV.
Scalable Internet of Things Network Design Using Multi-hop IEEE 802.11ah
Authors: Ahmed Nurzaman , Hussain Md. Iftekahr 
Published: April 2021

Abstract
The emerging IEEE 802.11ah is a promising communication standard for large-scale networks particularly the Internet of Things (IoT). The single-channel-based centralized channel access mechanism employed in 802.11ah does not scale well in such networks and leads to poor data reception quality. In this paper, we propose a multi-band sectorization and dynamic load balancing scheme for improving scalability. These features facilitate multi-hop communication more efficiently and enhance network capacity. Traffic congestion issues prevailing around the access point node due to the large volume of uplink traffic is mitigated by allowing simultaneous transmission using multiple orthogonal channels and sectors. Simulation and analytical results establish the essence of the novel protocol by showing significant improvements in terms of throughput and average packet delay over the existing schemes. The proposed network architecture improves throughput and delay performance up to 150% and 100% respectively compared to the relevant schemes.
Assessment of Small Strain Dynamic Soil Properties of Railway site Agartala, India by Bender Element Tests
Authors: Debnath Rajat , Saha Rajib , Haldar Sumanta 
Published: April 2021

Abstract
Small strain dynamic properties of soil is the primary input parameter in seismic ground response analysis studies. This study examines the small strain shear modulus (Gs or Gmax) and damping ratio (ξ) using bender element tests on subsoil samples along with evaluation of liquefaction potential (Sandy soil) collected from a railway construction site at Agartala, India. The objective of this study is to develop a database and empirical relationship on dynamic properties of soil Agartala which may help to carry out site specific seismic hazard studies of Agartala city. In present study, both undisturbed and disturbed soil samples were collected from twelve boreholes near the study area which is mainly of soft marshy ground with localized deposits of peat layer. Similar type of soil is often found in various parts of Agartala basin and other regions of India. Experimental results indicate that Vs, Gmax and ξ vary within a wide range depending upon the type of soil and a closed form empirical equation are proposed to calculate Gmax for different types of soil which would be applicable for evaluating dynamic properties for similar nature soil available across various sites of India.
Targeting ferroptosis protects against multiorgan dysfunction and death.
Authors: VandenBerghe Tom , Coillie Samya Van , Goetschalckx Ines , Wiernicki Bartosz , Mukhopadhyay Banibrata , Tonnus Wulf , San Emily Van , Choi Sze Men , Roelandt Ria , Dumitrascu Catalina , Lamberts Ludwig , Weyts Wannes , Huysentruyt Jelle , Ingold Irina , Lele Suhas , Meyer Evelyne , Seurinck Ruth , Saeys Yvan , Vermeulen An , Nuijs Alexander van , Conrad Marcus , Linkermann Andreas , Rajapurkar Mohan , Vandenabeele Peter , Hoste Eric , Augustyns Koen 
Published: April 2021

Abstract
Approximately half of all critically ill patients in the intensive care unit (ICU) develop multiorgan dysfunction1, which is responsible for 30% of deaths worldwide2,3. Besides life-supporting treatments, no cure exists for multiorgan dysfunction and its mechanisms are still poorly understood4. Catalytic iron is a detrimental factor associated with ICU mortality5,6 and is known to cause free radical-mediated cellular toxicity7. As such, catalytic iron is thought to induce excessive lipid peroxidation7, the main characteristic of an iron-dependent type of cell death conceptualized as ferroptosis8,9. Here we show that pharmacological targeting of ferroptosis with our most potent ferrostatin-analogue10 rescues from death in acute single and multiorgan dysfunction in mice, but not sepsis. Daily monitoring of critically ill ICU patients revealed that the peak level of malondialdehyde, reflecting excessive lipid peroxidation, correlates with multiorgan dysfunction and death. Our results demonstrate that ferroptosis targeting is life-saving in experimental models of critical illness and that monitoring of malondialdehyde can allow patient stratification. Therefore, controlling the extent of ferroptosis in non-septic patients with multiorgan dysfunction could become a novel treatment for one of the major causes of global deaths.
Rhenium distribution and behaviour in the salinity gradient of a highly stratified estuary and pristine riverine waters
Authors: bura-Nakić Elvira , Knežević Lucija , Mandić Jelena , Cindrić Ana-Marija , Omanović Dario 
Published: April 2021

Abstract
The abundance and distribution of dissolved Re (DRe) has been determined in the freshwater part of the Krka River (Croatia), draining the karstic carbonate landscape, as well as in the salinity gradient of its highly stratified estuary. Due to low DRe concentration, the batch procedure consisting of pre-concentration step using an anion exchange resin (Dovex) and analysis of DRe in 8 M HNO 3 eluate using a high resolution inductively coupled plasma mass spectrometry (HR ICP-MS) was adopted. Due to the potential inconsistent recoveries, ranging from 60% to 87%, the quantification was performed by using the isotope dilution (ID) technique. The DRe concentration in the Krka River basically increased in the downstream direction, with the 6.2 pM at the spring site, reaching 11.9 pM before the estuarine region. The weathering of the surrounding carbonate lithology is assumed as the source of natural Re. The two specific anomalies were registered: a strong increase in DRe concentration due to the anthropogenic input near the town of Knin (27.5 pM) and a decrease at downstream site caused by the subterranean input of freshwater of the Zrmanja River leading to relatively low DRe concentration (8.5 pM). In the estuarine segment, a near-conservative behavior of DRe was found in the salinity gradient of the upper surface layer, with the DRe concentration ranging from 18 to 38 pM. An anthropogenic supply was suggested within the estuarine segment close to the urban area causing a small positive deviation from the conservative line. In the bottom seawater layer, a minor decrease of DRe concentration in the most upstream estuarine regions was evidenced, implying a potential weak scavenging of Re.
Dynamic Change in Regional Resilience Indicators After a Disaster: A Comprehensive Assessment of Sichuan After the 2008 Wenchuan Earthquake
Authors: Lu Yi , Shi Xiaoyuan , Mao Xiai , Wang Shihang 
Published: April 2021

Abstract
Regional resilience after a disaster is a process that encompasses resistance, recovery and redevelopment. However, there have been few longitudinal dynamic analyses using resilience indicators after a disaster. This research proposes an ordination and clustering-based method for regional resilience evaluations focused on short-term disaster-resistance and long-term disaster-recovery capacities in the affected counties. This method was proven to be effective on data from 55 counties before and after the 2008 Wenchuan Earthquake (2005-2016) in Sichuan Province, China. It was found that: (i) economic related indicators were often negatively affected by the disaster over the short term, especially in the severely affected counties; (ii) the degree of economic development and the devastation extent significantly affected the recovery trends of two macro-economic indicators: the primary industry and the private economy; and (iii) the recovery trends in most counties for some economic and social indicators were initially stagnant or had a slow recovery for 1-3 years, after which there was a rapid recovery process. The intuitive and informative results from this evaluation provide a better understanding of the dynamic regional resilience process after a disaster.
iTRAQ-Based Quantitative Proteomics Analysis of Sprague-Dawley Rats Liver Reveals Perfluorooctanoic Acid-Induced Urea Metabolism Dysfunction
Authors: Liu Hui , Liu Fangfang , Zhou Yongbing , Griffin Nathan , Faulkner Sam , Cui Huixian , Wang Li 
Published: April 2021

Abstract
Perfluorooctanoic acid (PFOA) is a typical C8 representative compound of perfluoroalkyl and polyfluoroalkyl substances (PFAS) widely used in industrial and domestic products. It is a persistent organic pollutant found in the environment as well as in the tissues of humans and wildlife. Despite emerging scientific and public interest, the precise mechanisms of PFOA toxicity remain unclear. In this study, male rats were exposed to 1.25, 5, and 20 mg PFOA/kg body weight/day for 14 days. Urine samples were also collected and monitored by raising rats in metabolic cages. In vivo results demonstrate that PFOA exposure induces significant hepatocellular hypertrophy and reduced urea metabolism. iTRAQ-based quantitative proteomics analysis of Sprague-Dawley (SD) rats livers identified 3,327 non-redundant proteins of which 112 proteins were significantly upregulated and 80 proteins were downregulated. Gene ontology analysis revealed proteins are primarily involved in cellular, metabolic and single − organism processes. Among them, eight proteins (ACOX1, ACOX2, ACOX3, ACSL1, EHHADH, GOT2, MTOR and ACAA1) were related to oxidation of fatty acids and two proteins (ASS1 and CPS1) were found to be associated with urea cycle disorder. The downregulation of urea synthesis proteins ASS1 and CPS1 after exposure to PFOA was then confirmed through qPCR and western blot analysis. Together, these data demonstrate that PFOA exposure directly influences urea metabolism and identify CPS1 as a potential regulatory target.
Breast Cancer Prognosis: A Genetic Code for Personalized Therapy
Authors: Rulli Antonio , Fortuna Laura , Zayik Svitlana , Covarelli Piero , Stracci Fabrizio , Pelliccia Cristina , Sidoni Angelo , Barberini Francesco 
Published: April 2021

Abstract
Background: Breast cancer is distinguished in three different subtypes, based on clinical and molecular parameters: Luminal - HER2 - Basal type. Luminal carcinomas (which represent about 65% of the total) are distinguished by a particular heterogeneity of biological behaviour with disease recovery in about 40-50% and death in about two-thirds of these patients at 5 years from diagnosis, despite initial anatomopathological pictures of apparent low aggressiveness. Precisely, more biomolecular parameters are desirable for this diagnostic category which starting from an estimated disease recovery can guide therapeutic choices in a more articulated way that is modelled on the actual needs.Method: The aim of this work is to build a panel of genes that can be used to personalize therapy and consequently reduce mortality. Our kit is patented and includes 33 genes that best characterize neoplastic heterogeneity and sensitivity to drugs. The study involved the total transcriptome (RNA) sequencing of 40 patient samples carried out in the two-year period 1994/1995 with the aim of identifying a group of genes expressed differentially among patients with good prognosis and those with poor prognosis. Results: Total RNA extraction from formalin-fixed, paraffin-embedded samples and then Library preparation for RNA-Seq was achieved. The study highlighted some genes: CXCL13 life gene, IFITM10 death gene always present regardless of molecular subtype, and DSCAM-AS1 gene, specific for Luminal A subtype, that if present, let the patient avoid standard PBI and neoadjuvant therapy. Conclusion: The goal is to implement a different surgical and adjuvant personalized therapy for every single patient.
Research on the Coordinated Development of Resources, Environment, and Economy in the Yellow River Basin
Authors: ZHAO Jinhui , WANG Yufeng , XIA Yongbo , ZHANG Lijun 
Published: April 2021

Abstract
Background：The high-quality development in the Yellow River Basin has to be fostered by the coordination of resources, environment, and economy. Therefore, conducting an analysis on the coupling level of resources, environment, and economy in the Yellow River Basin is of major significance to the research on its high-quality development path. Methods：Based on the data of the nine provinces in the Yellow River Basin from 2004 to 2017, a coupling development model is constructed for an analysis of the coupling level in this area and a modeling prediction. A comprehensive evaluation of the development level of Resources-Environment-Economy system and the subsystems in the Yellow River Basin is performed by combining the range change method and entropy weight method. Results：The result shows that despite the rising coupling level of resources, environment, and economy in the Yellow River Basin, the comprehensive evaluation value of the environment subsystem is low, which was merely 0.109 in 2017 and has remained unchanged between 2009 and 2017, resulting in a low coupling coordination degree of Resources-Environment-Economy. In 2017, the coupling coordination degree was only 0.454. The development was on the verge of imbalance and the high-quality coordinated development of the Yellow River Basin has been restricted. The simulated prediction indicates that the coordinated development of Resources-Environment-Economy in the Yellow River Basin can only be realized by overcoming the disadvantages of the ecological and economic systems. Conclusions：When the comprehensive evaluation value of environmental subsystem increases by 0.2 and that of economic subsystem increases by 0.1, all the systems are just coordinated; when the comprehensive evaluation value of each subsystem reaches 0.65, the development of the systems of Resources-Environment-Economy in the Yellow River Basin are well coordinated.