bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Bio‐Inspired Event‐Driven Mechanoluminescent Visuotactile Sensor for Intelligent Interactions
Authors: Sou Kit‐Wa , Chan Wang‐Sing , Lei Kai‐Chong , Wang Zihan , Li Shoujie , Peng Dengfeng , Ding Wenbo 
Published: January 2025

AbstractEvent‐driven sensors are essential for real‐time applications, yet the integration of current technologies faces limitations such as high cost, complex signal processing, and vulnerability to noise. This work introduces a bio‐inspired mechanoluminescence visuotactile sensor that enables standard frame‐based cameras to perform event‐driven sensing by emitting light only under mechanical stress, effectively acting as an event trigger. Drawing inspiration from the biomechanics of canine teeth, the sensor utilizes a rod‐patterned array to enhance mechanoluminescent signal sensitivity and expand the contact surface area. In addition, a machine learning‐enabled algorithm is designed to accurately analyze the interaction‐triggered mechanoluminescence signal in real‐time. The sensor is integrated into a quadruped robot's mouth interface, demonstrating enhanced interactive capabilities. The system successfully classifies eight interactive activities with an average accuracy of 92.68%. Comprehensive tests validate the sensor's efficacy in capturing dynamic tactile signals and broadening the application scope of robots in interaction with the environment.
Ultrasound‐Controllable Release of Carbon Monoxide in Multifunctional Polymer Coating for Synergetic Treatment of Catheter‐Related Infections
Authors: Liang Ziqing , Sun Rui , Zhang Xu , Luan Shifang , Xu Hong , Wang Rui , Song Lingjie , Shi Hengchong , Wang Lei 
Published: January 2025

AbstractMedical catheters are susceptible to biological contamination and pathogen invasion, leading to infection and inflammatory complications. The development of antimicrobial coatings for medical devices has emerged as a promising strategy. However, limited biological functionality and the incompatibility between bactericidal properties and biosafety remain great challenges. Herein, a multifunctional polymer coating (CPB‐Ac) is created, incorporating an ultrasonic‐responsive carbon monoxide release unit (CORM‐Ac) and antifouling unit to treat catheter‐related complications. As‐synthesized CPB‐Ac polymer can be stably anchored to various medical devices with arbitrary shapes and compositions via facile UV treatment. Both in vivo and vitro experiments demonstrated that this multi‐functional coating exhibits anti‐fouling, anti‐inflammatory, and broad‐spectrum antibacterial activities as well as good biosafety. During the initial implantation phase, the antifouling units of CPB‐Ac coating effectively inhibit the attachment of biological contaminants, significantly reducing the risk of thrombosis and bacterial infection. Once bacterial infection occurs, ultrasonic irradiation can activate CPB‐Ac coating to release CO with a much higher amount of 55.3 µm than non‐ultrasound controls, therefore rapidly eliminating bacteria and alleviating inflammatory response. It is believed that the work may provide an effective method for the development of next‐generation intelligent medical coatings against catheter‐related complications.
Tunable Bicontinuous Macroporous Cell Culture Scaffolds via Kinetically Controlled Phase Separation
Authors: Dudaryeva Oksana Y. , Cousin Lucien , Krajnovic Leila , Gröbli Gian , Sapkota Virbin , Ritter Lauritz , Deshmukh Dhananjay , Cui Yifan , Style Robert W. , Levato Riccardo , Labouesse Céline , Tibbitt Mark W. 
Published: January 2025

Abstract3D scaffolds enable biological investigations with a more natural cell conformation. However, the porosity of synthetic hydrogels is often limited to the nanometer scale, which confines the movement of 3D encapsulated cells and restricts dynamic cell processes. Precise control of hydrogel porosity across length scales remains a challenge and the development of porous materials that allow cell infiltration, spreading, and migration in a manner more similar to natural ECM environments is desirable. Here, a straightforward and reliable method is presented for generating kinetically‐controlled macroporous biomaterials using liquid–liquid phase separation between poly(ethylene glycol) (PEG) and dextran. Photopolymerization‐induced phase separation resulted in macroporous hydrogels with tunable pore size. Varying light intensity and hydrogel composition controlled polymerization kinetics, time to percolation, and complete gelation, which defined the average pore diameter (Ø = 1–200 µm) and final gel stiffness of the formed hydrogels. Critically, for biological applications, macroporous hydrogels are prepared from aqueous polymer solutions at physiological pH and temperature using visible light, allowing for direct cell encapsulation. Human dermal fibroblasts in a range of macroporous gels are encapsulated with different pore sizes. Porosity improved cell spreading with respect to bulk gels and allowed migration in the porous biomaterials.
Slide‐Ring Structured Stress‐Electric Coupling Hydrogel Microspheres for Low‐Loss Transduction Between Tissues
Authors: Wang Fan , Han Xiaoyu , Han Zeyu , Wang Juan , Cai Zhengwei , Chen Gang , Bai Dingqun , Cui Wenguo 
Published: January 2025

AbstractHigh transductive loss at tissue injury sites impedes repair. The high dissipation characteristics in the electromechanical conversion of piezoelectric biomaterials pose a challenge. Therefore, supramolecular engineering and microfluidic technology is utilized to introduce slide‐ring polyrotaxane and conductive polypyrrole to construct stress‐electric coupling hydrogel microspheres. The molecular slippage mechanism of slide‐ring structure stores and releases mechanical energy, reducing mechanical loss, the piezoelectric barium titanate enables stress‐electricity conversion, and conjugated π‐electron movement in conductive network improves the internal electron transfer efficiency of microspheres, thereby reducing the loss in stress‐electricity conversion for the first time. Compared to traditional piezoelectric hydrogel microspheres, the stress‐electric coupling efficiency of low‐dissipation microspheres increased by 2.3 times, and the energy dissipation decreased to 43%. At cellular level, electrical signals generated by the microspheres triggered Ca2+ influx into stem cells and upregulated the cAMP signaling pathways, promoting chondrogenic differentiation. Enhanced electrical signals induced macrophage polarization to the M2 phenotype, reshaping inflammation and promoting tissue repair. In vivo, the low‐dissipation microspheres restored low‐loss transduction between tissues, alleviated cartilage damage, improved behavioral outcomes, and promoted the treatment of osteoarthritis in rats. Therefore, this study proposes a new strategy for restoring low‐loss transduction between tissues, particularly in mechanically sensitive tissues.
3D‐Printed Electrohydrodynamic Pump and Development of Anti‐Swelling Organohydrogel for Soft Robotics
Authors: Xin Yangyang , Zhou Xinran , Tan Ming Rui Joel , Chen Shaohua , Huang Peiwen , Jiang Yawei , Wu Wenting , Gao Dace , Lv Jian , Magdassi Shlomo , Lee Pooi See 
Published: January 2025

AbstractThis study introduces advancements in electrohydrodynamic (EHD) pumps and the development of a 3D‐printable anti‐swelling organohydrogel for soft robotics. Using digital light processing (DLP)technology, precise components with less than 1% size variation are fabricated, enabling a unique manifold pump array. This design achieves an output pressure of 90.2 kPa—18 times higher than traditional configurations—and a flow rate of 800 mL min−1, surpassing previous EHD pumps. To address swelling issues in dielectric liquids, a novel organohydrogel is developed with Young's modulus of 0.33 MPa, 300% stretchability, and a swelling ratio under 10%. Its low swelling is attributed to the shield effect and edge length confinement effect. This durable material ensures consistent pump performance under mechanical stresses like bending and twisting, crucial for dynamic soft robotic environments. These innovations significantly improve EHD pump efficiency and reliability, expanding their potential applications in soft robotics, bioengineering, and vertical farming.
Maximizing the Electrochemical Performance of Supercapacitors by Using Seawater Electrolyte Instead of Acidic/Lithium‐Based Electrolytes
Authors: Garcés‐Patiño Luis Antonio , Esquivel‐Castro Tzipatly Angelica , Viesca Efrain , Mtz‐Enriquez Arturo Isaias , Martinez‐Gomez Alvaro de Jesus , Rosu Haret Codratian , Perez‐Mayen Leonardo , Oliva Jorge 
Published: January 2025

AbstractThe electrochemical performance of supercapacitors (SCs) was evaluated by using different inorganic electrolytes: seawater, acidic‐electrolyte (polyvinyl‐alcohol (PVA)/H3PO4) and Li‐based electrolyte (synthesized from expired LIB‐electrodes and named as ERB‐electrolyte). SCs made only with graphene electrodes and PVA/H3PO4 electrolyte exhibited a capacitance/energy‐density of 421.4 F g−1/58.5 W·h kg−1. After adding the G/SiO2/MgO (GSM) and G/SiO2/MgO‐MnO2 (GSMM) nanocomposites to the SC electrodes, the capacitance increased by 36% and 69%, respectively. To develop an environmentally friendly SC, we substituted the acidic electrolyte with seawater or ERB electrolyte and compared their electrochemical performance. SCs made GSM and GSMM composites (seawater was the electrolyte) showed specific capacitances/energy‐densities of 679.7 F g−1/94.4 W·h kg−1 and 852.3 F g−1/118.5 W·h kg−1, respectively, which were ∼20% higher compared with these for SCs made with acidic‐electrolyte. SCs made with ERB‐electrolyte and GSMM composite had a lower capacitance (683.3 F g−1) in comparison with SCs made with GSMM/acidic electrolyte (710.4 F g−1). Electrochemical‐impedance‐ spectroscopy (EIS) analysis demonstrated that the lowest charge‐transfer‐resistance and series‐resistance were obtained in SCs made with seawater‐electrolyte, therefore, those SC had the most efficient ion storage/diffusion. Finally, UV‐Vis/Raman/XPS studies revealed the presence of oxygen‐vacancies, Mg2+/Mg0, Mn4+/Mn3+, and Si4+/Si3+/Si2+ species on the SC electrodes (active‐redox‐centers to store charge).
Neighborhood resources and stressors associated with parenting inputs for children's learning and development
Authors: Lanteri Lindsay , Miller Portia , Votruba‐Drzal Elizabeth , Coley Rebekah Levine 
Published: January 2025

AbstractPrior research has assessed the ways in which neighborhoods promote or inhibit children's development but has paid less attention to delineating the particular processes through which neighborhoods are linked to child outcomes. This study combines geospatial data with survey data from the Early Childhood Longitudinal Study Kindergarten Cohort of 2010–2011, a nationally representative sample of kindergarteners followed through 5th grade (N ~ 12,300), to explore how differences in neighborhood resources (parks and services) and stressors (crime and neighborhood disadvantage) are associated with variations in parental inputs—school involvement and provision of out‐of‐home enrichment activities. Using multilevel models assessing within‐ and between‐family associations, we found mixed evidence concerning how neighborhood features are linked to parental inputs. Considering within‐family changes in neighborhood contexts, concentrated disadvantage negatively predicted parental inputs, particularly following a move to a more disadvantaged neighborhood. Results were more consistent between families: concentrated disadvantage was associated with lower school involvement and out‐of‐home enrichment, while community services and parks were associated with more involvement and enrichment. Neighborhood crime was not associated with parental inputs. Results shed light on methodological limitations of neighborhood effects research and suggest the need for more rigorous methods, such as natural experiments which can capture exogenous changes in neighborhood processes.
Whole genome methylation sequencing in blood from persons with mild cognitive impairment and dementia due to Alzheimer's disease identifies cognitive status
Authors: Madrid Andy , Papale Ligia A. , Bergmann Phillip E. , Breen Coleman , Clark Lindsay R. , Asthana Sanjay , Johnson Sterling C. , Keleş Sündüz , Hogan Kirk J. , Alisch Reid S. 
Published: January 2025

AbstractINTRODUCTIONWhole genome methylation sequencing (WGMS) in blood identifies differential DNA methylation in persons with late‐onset dementia due to Alzheimer's disease (AD) but has not been tested in persons with mild cognitive impairment (MCI).METHODSWe used WGMS to compare DNA methylation levels at 25,244,219 CpG loci in 382 blood samples from 99 persons with MCI, 109 with AD, and 174 who are cognitively unimpaired (CU).RESULTSWGMS identified 9756 differentially methylated positions (DMPs) in persons with MCI, including 1743 differentially methylated genes encoding proteins in biological pathways related to synapse organization, dendrite development, and ion transport. A total of 447 DMPs exhibit progressively increasing or decreasing DNA methylation levels among CU, MCI, and AD that correspond to cognitive status.DISCUSSIONWGMS identifies DMPs in known and newly detected genes in blood from persons with MCI and AD that support blood DNA methylation levels can distinguish cognitive status.Highlights
Whole genome methylation levels in blood from 99 persons with mild cognitive impairment (MCI), 109 with Alzheimer's disease, and 174 who are cognitively unimpaired were analyzed.
Nine thousand seven hundred fifty‐six differentially methylated positions (DMPs) were identified in MCI.
One thousand seven hundred forty‐three genes comprise one or more DMPs in persons with MCI.
Fifty‐eight DMPs and 392 differentially methylated genes are shared among the three pairwise comparisons.
Four hundred forty‐seven DMPs exhibit progressive changes that correspond to cognitive status.
Photoinduced Energy/Electron Transfer within Single‐Chain Nanoparticles
Authors: Nagao Masanori , Mundsinger Kai , Barner‐Kowollik Christopher 
Published: January 2025

AbstractWe demonstrate that single‐chain nanoparticles (SCNPs) – compact covalently folded single polymer chains – can increase photocatalytic performance of an embedded catalytic center, compared to the comparable catalytic system in free solution. In particular, we demonstrate that the degree of compaction allows to finely tailor the catalytic activity, thus evidencing that molecular confinement is a key factor in controlling photocatalysis. Specifically, we decorate a linear parent polymer with both photoreactive chalcone moieties as well as Ru(bpy)3 catalytic centers. We initially construct a SCNP via a photosensitized [2+2] cycloaddition at 510 nm and demonstrate that the SCNP formation is substantially more efficient when the Ru(bpy)3 units are part of the polymer chain instead of as free molecules in solution. Subsequently, we employ the same Ru(bpy)3 units as photocatalysts in a model reaction employing pyrene units as charge transfer moieties. We establish that the photocatalytic activity increases as the polymer becomes more compact, reaching peak efficiency, followed by a subsequent decline as the SCNP becomes too compact. Thus, we identify a goldilocks regime of catalyst confinement via SCNP compaction for use in photocatalysis.
MOF‐Based Dual‐Layer Pickering Emulsion: Molecular‐Level Gating of Water Delivery at Water‐Oil Interface for Efficient Photocatalytic Hydrogenation Using H2O as a Hydrogen Source
Authors: Yuan Kuo , Zhang Ying , Yan Zhuang , Yun Qinbai , Song Tianqun , Guo Jun , Feng Jie , Chen Zheng , Zhang Xiaotao , Tang Zhiyong , Hu Wenping , Lu Tongbu 
Published: January 2025

AbstractBiphasic system not only presents a promising opportunity for complex catalytic processes, but also is a grand challenge in efficient tandem reactions. As an emerging solar‐to‐chemical conversion, the visible‐light‐driven and water‐donating hydrogenation combines the sustainability of photocatalysis and economic‐value of hydrogenation. However, the key and challenging point is to couple water‐soluble photocatalytic hydrogen evolution reaction (HER) with oil‐soluble hydrogenation. Herein, we employed metal–organic frameworks (MOFs) and CdS nanorods to construct a MOF‐CdS dual‐layer Pickering emulsion (water in oil, W/O), which compartmented aqueous phase for photocatalytic HER and oil phase for hydrogenation. The hydrophobic MOF and hydrophilic CdS were isolated at the inner and outer layers of W/O emulsion, respectively. The molecularly regulated hydrophobicity of MOF controlled the water delivery onto CdS photocatalysts, which realized the synergistic regulation of HER and hydrogenation. In the photocatalytic hydrogenation of cinnamaldehyde, the highest yield of MOF‐CdS Pickering emulsion reached 187.37 mmol ⋅ g−1 ⋅ h−1, 30 times that of the counterpart without emulsion (6.44 mmol ⋅ g−1 ⋅ h−1). Its apparent quantum yield reached 43.24 % without co‐catalysts. To our knowledge, this performance is at a top‐level so far. Our work realized the precise regulation of water‐oil interface to effectively couple two reactions in different phases, providing new perspective for challenging tandem catalysis.
Autocatalytic Interfacial Synthesis of Self‐Standing Amide‐Linked Covalent Organic Framework Membranes
Authors: Fang Lei , Xu Hui , Qiu Suyu , Ye Tao , Wang Tianqi , Shang Jin , Gu Cheng , Kitagawa Susumu , Li Liangchun 
Published: January 2025

AbstractThe synthesis of crystalline covalent organic frameworks (COFs) has in principle relied on reversible dynamic chemistry. A general method to synthesize irreversibly bonded COFs is urgently demanded for driving the COF chemistry to a new era. Here we report a universal two‐step method for the straightforward synthesis of irreversibly amide‐linked COF (AmCOF) membranes by autocatalytic interfacial polymerization (AIP). Highly crystalline amide and imine bilinker COF (AICOF) membranes are readily synthesized by AIP strategy which ingeniously leverages interfacial polymerization to generate amide units followed by an autocatalytic condensation that forms imine bonds. Then, the fully amide‐linked AmCOF membranes with Turing structures can be prepared through irreversible linker renovation. The universality of this method has been exemplified by nine AmCOF membranes. Among them, the AmCOF‐1 membrane exhibits superior performance for H2O2 photosynthesis (4353 μmol g−1 h−1) and high stability, enabling continuous production of H2O2 under sunlight for 150 h without sacrificial agents. Mechanistic investigations reveal that the greatly improved properties are attributable to the built‐in robust amide knots, facilitating full separation of electrons and holes, ultra‐long exciton diffusion length, and fast dissociation of excitons within the AmCOF channels.
Electrosynthesis of Mussel‐inspired Adhesive Polymers as a Novel Class of Transient Enzyme Stabilizers
Authors: Neubert Tilmann J. , Hielscher Maximilian M. , Walter Keven , Schröter Carolin M. , Stage Marion , Rosencrantz Ruben R. , Panis Felix , Rompel Annette , Balasubramanian Kannan , Waldvogel Siegfried R. , Börner Hans G. 
Published: January 2025

AbstractMultifunctional ortho‐quinones are required for the formation of thiol‐catechol‐connectivities (TCC) but can be delicate to handle. We present the electrochemical oxidation of the dipeptide DiDOPA, achieving up to 92 % conversion efficiency of the catechols to ortho‐quinones. Graphite and stainless steel could be employed as cost‐efficient electrodes. The electrochemical activation yields quinone‐solutions, which are free of undesired reactive compounds and eliminates the challenging step of isolating the reactive quinones. The DiDOPA quinones were employed in polyaddition reactions with multi‐thiols, forming oligomers that functioned as transient enzyme stabilizers (TES). These TCC‐TES‐additives improved the thermal stability and the activity of tyrosinase in heat stress assays.
Photocatalytic Dehalogenation of Aryl Halides Mediated by the Flexible Metal–Organic Framework MIL‐53(Cr)
Authors: Luo Tian , Jeppesen Henrik S. , Schoekel Alexander , Bönisch Nadine , Xu Fei , Zhuang Rong , Huang Qiang , Senkovska Irena , Bon Volodymyr , Heine Thomas , Kuc Agnieszka , Kaskel Stefan 
Published: January 2025

AbstractThe catalytic potential of flexible metal–organic frameworks (MOFs) remains underexplored, particularly in liquid‐phase reactions. This study employs MIL‐53(Cr), a prototypical “breathing” MOF capable of structural adaptation via pore size modulation, as a photocatalyst for the dehalogenation of aryl halides. Powder X‐ray diffraction and Pair Distribution Function analyses reveal that organic solvents influence pore opening, while substrates and products dynamically adjust the framework configuration during catalysis. This structural flexibility enables precise tuning of photocatalytic efficiency via solvent‐mediated control of the pore aperture. The results demonstrate that the dynamic behavior of MIL‐53(Cr) facilitates enhanced catalytic activity and selectivity, advancing the application of flexible MOFs as tunable, enzyme‐mimicking catalysts. These findings pave the way for the rational design of next‐generation flexible photocatalysts.
Enhanced Water Splitting with Sulfur‐Doped Nickel Ferrite for Green Hydrogen at Industrial Current Density
Authors: Rosh Tom Deepa , Shah Ayushi , Modi Krishna H. , Majethiya Ajay , Pataniya Pratik M. , Sumesh C. K. 
Published: January 2025

AbstractThe main challenge for water electrolysis is that continuous and effective hydrogen evolution at high current densities is unattainable due to the quick degradation of performance that occurs with extended large‐current operation. In this work, sulfur‐doped nickel ferrite nanocomposites were prepared using simple hydrothermal method with the objective of improving electrocatalytic green hydrogen production at industrial current densities. X‐ray diffraction (XRD), scanning electron microscopy (SEM), and X‐ray photoelectron spectroscopy (XPS) were used to analyse the crystalline structure, morphology, and chemical composition of the synthesised nanocomposites. The prepared S−NiFe2O4/NF (NS‐85) catalyst exhibits excellent electrochemical water‐splitting activity, a low overpotential, a high current density, and extended stability lasting more than 12 hours. The NS‐85/NF electrode has a cathodic current density of 300 mA cm−2 at −0.329 V overpotential and at the lowest overpotential of −0.264 V, the electrode has a current density of 100 mA cm−2. Our work provides new approaches to the development of earth‐abundant, stable, scalable, and highly effective catalysts for industrial water electrolysis.
Solution‐Processed MoS2‐Expanded Graphite as a Fast‐Charging Anode for Lithium‐Ion Batteries
Authors: Lobo Kenneth , Moolayadukkam Sreejesh , Vishwanathan Savithri , Ramakrishna Matte H. S. S. 
Published: January 2025

AbstractThe widespread demand for battery‐powered technologies has propelled the search for efficient and commercially viable electrode materials with fast‐charging abilities. Reported herein is an MoS2‐expanded graphite (EG) composite as a stable and high‐rate lithium‐ion battery (LIB) anode, delivering specific capacities of 796 mAh g−1 at 0.5 A g−1 and 320 mAh g−1 at 20 A g−1 over 400 cycles. Cyclability at extreme rates up to 50 A g−1 (~103 mAh g−1) illustrates its scope for fast charging applications. As a result of the processing technique, the exfoliated nanosheets have good interfacial contact which aids in charge transfer and maintaining structural integrity during continuous battery operation. Further, analytical electrochemical methods suggest a predominance of pseudocapacitive charge storage mechanism, explaining the anode performance at high rates.