bluuebunny/crossref_metadata_2025_split huggingface dataset:
Whipple procedure for ampulla of Vater cancer in a patient with situs inversus (clinical case)
Authors: Ischenko R. V. , Sedakov I. E. , Antipov V. N. , Ivanov Y. V. , Lysenko A. O. , Stankevich V. R. , Smirnov A. V. 
Published: March 2021

A clinical case of a rare combination of complete transposition of internal organs (situs inversus totalis) with adenocarcinoma of the major duodenal papilla is presented. In addition to situs vicserum inversus, the patient has a special variant of vascular anatomy that is not included in the generally accepted classification of variants of arterial liver anatomy according to Michaels N.A. (1955), namely: separate separation of the left and right hepatic arteries from the ventral trunk. After individual preoperative planning, a patient with a complete reverse position of the abdominal organs and non-standard vascular anatomy was performed Whipple procedure. Non-invasive CT angiography is important in a complex preoperative examination, which allows timely identification and clarification of frequently occurring features of blood supply to the hepatopancreatoduodenal zone in patients with situs inversus totalis. Such surgical interventions should be performed in large multi-specialty medical centers that have extensive experience in performing pancreatoduodenal resections.
The review of international clinical guidelines and clinical trial results for the diagnosis of hepatocellular cancer (HCC) for the period 2014–2020
Authors: Kаrmаzаnovsky G. G. , Shantarevich M. Yu. 
Published: March 2021

The purpose of this publication is to analyze international clinical guidelines and clinical trial data on the diagnosis of hepatocellular carcinoma and demonstrate the possibilities of using MRI with hepatobiliary magnetic resonance contrast agent. As well as an evaluation its diagnostic advantages in comparison with other diagnostic methods such as ultrasound, CT and MRI with extracellular contrast agents.Material and methods. Abstracts of 331 scientific articles for the period 2014–2020 were selected in the PubMed information and analytical system for the keywords: “hepatocellular carcinoma”, “US”, “CT”, “MRI”, “gadoxetic acid”. Articles about technical aspects and clinical cases were excluded. After the analysis of full-text articles, 32 publications were selected.Results. The presented review has demonstrated the diagnostic advantages of MRI with hepatobiliary magnetic resonance contrast agents and a wide range of its application at all stages of care for a patient with hepatocellular carcinoma.Conclusion. Despite the existing variety of methods for diagnosing hepatocellular carcinoma, the leading direction in this area is currently MRI with gadoxetic acid. The high diagnostic efficiency of gadoxetic acid makes it possible to increase the accuracy of the imaging and to choose the optimal management for each patient.
Influence of the low-dose CE-MDCT scanning protocol parameters on the results of pancreatic ductal adenocarcinoma radiomic analysis
Authors: Tikhonova V. S. , Karmazanovsky G. G. , Kondratyev E. V. , Gruzdev I. S. , Glotov A. V. 
Published: March 2021

To investigate the dependence of textural parameters of pancreatic ductal adenocarcinoma on using standard and low-dose CT protocols.Materials and methods. The study included 52 consecutive patients with histologically confirmed pancreatic ductal adenocarcinoma who underwent contrast enhanced computed tomography using standard (120 kV) and low-dose (100 kV) scanning protocols. We compared radiomics features of the identical histological tumors in all scanning phases.Results. We calculated 53 radiomics features in all types of pancreatic ductal adenocarcinoma grade differentiation for all scanning phases. We identified that out of 53 features of texture analysis, less than half was statistically different for each scan phase (11 parameters (20.8%) for the unenhanced phase; 18 parameters (34%) for the arterial; 19 parameters (35.8%) for the venous and delayed scanning phases), in all types of tumor differentiation (GLCM_ Contrast, GLCM_Correlation, GLCM_Dissimilarity, GLRLM_SRHGE etc., p < 0.05).The diagnostic accuracy of more than 50% of the radiomics features is preserved when changing kV in the CT scan protocol.Conclusion. The use of a low-dose CT protocol doesn’t affect the diagnostic accuracy of the features of texture analysis in the preoperative assessment of the degree of differentiation of pancreatic ductal adenocarcinoma.
Computed tomography in planning of the treatment of complications after pancreatic surgery
Authors: Shrainer I. V. , Pershina E. S. , Dalgatov K. D. , Kozodaeva M. V. 
Published: March 2021

Aim. To evaluate opportunity of computed tomography in diagnosis and decision making in patients with pancreatic surgery complications and possibility of interventional procedures in its treatment.Materials and methods. 50 patients underwent pancreatic surgery in 2018-2020 (45 Whipple procedure and 5 distal pancreatectomies). 45 patients underwent computed tomography in post-surgery course. The complications occur in 29 patients; complications were found by computer tomography in 26 patients.Results. The most frequent complication was pancreatic fistula (24%) in typical places: upper edge of the pancreatojejunostomy (25%) and in the bed of the resected pancreatic head (50%). Delineated fluid collections on computed tomography scans were more prevalent in patients with complicated course (57.9% vs. 26.3%). The average size of fluid collections was increased in the group of complicated courses (51,9 × 28,1 mm vs. 42,2 × 20, 6 mm). Interventional procedures were performed in 18 patients (62% of complicated patients). The average number of such interventions per patient was 2.95. Using interventional techniques as the only method of surgical treatment, 13 patients were cured (50% of complicated patients). In 14 patients, interventions were planned and performed based on control computed tomography. Postoperative bleedings were detected in 8 patients (16%). In 4 cases it revealed ongoing bleeding by computer tomography, in 3 cases – completed, which allowed us to determine further treatment tactics.Conclusion. Performing computed tomography after pancreatic surgery allows to identify postoperative complications before their clinical manifestation and plan their treatment. The optimal time for performing computed tomography is 5–6 days after surgery. Performing CT angiography for suspected bleeding in some cases allows to avoid invasive angiography and choose the method of endovascular hemostasis in appropriate situations. The combination of various interventional techniques allows to avoid relaparotomy in most patients with intraabdominal complications.
Additional criterion for assessing the risk of gastric variceal bleeding according to multispiral computed tomography
Authors: Yudin A. L. , Yumatova E. A. , Yagubova K. V. 
Published: March 2021

Aim. To establish the parameters of gastric varices which determine a high risk of gastric bleeding according to the results of multispiral computed tomography.Material and methods. The results of studies of 39 patients with liver cirrhosis and gastric varices were retrospectively studied. Nine of them had signs of previous bleeding on endoscopic examination or the corresponding data in the medical history. In 3 patients gastric bleeding occurred 30-47 days after multispiral computed tomography.Results. According to the results of multispiral computed tomography with multiplanar reconstructions gastric bleeding was detected in 12 patients with protrusion of submucosal varicose veins into the gastric lumen by 5 mm or more with a vein diameter >7 mm.Conclusion. The results of multispiral computed tomography, complemented by the hydro-computed tomography technique, provide important additional information on predicting the development of gastric bleeding in the selection of patients for preventive minimally invasive interventions on the veins of the stomach.
Full-split liver transplantation. The first experience in Russian Federation
Authors: Voskanyan S. E. , Kolyshev I. Yu. , Shabalin M. V. , Artemyev A. I. , Rudakov V. S. , Maltseva A. P. , Bashkov A. N. , Syutkin V. Е. , Gubarev К. К. , Svetlakova D. S. 
Published: March 2021

Aim. To present the first successful full-split liver transplantation for two adults recipients in Russia.Materials and methods. The first successful full-split liver transplantation for two adults in ex situ way in Russia was made on 26th of September 2014 in the Burnasyan Federal Medical Biophysical Center of FMBA. The deceased donor was inside UNOS, Lee. The GRWR index in both recipients was near 1. The first recipient had been in a waiting list for 1 year, the second for 4 months. Both recipients had got liver cirrhosis in terminal stage.Results. The surgical procedure length was 650 and 660 min. The overall time of cold ischemia was 510 min. We observed a primary function of each graft. ISGLS B and Clavien-Dindo 3A biliary leak complications were observed in both recipients. Both patients were discharged after 33 and 34 days. Overall survival for this moment is 68 months.Conclusion. Full-split liver transplantation for two adults in ex situ way seems to be a complicated procedure both from the technical and organizing points of view. It demanding good mastership and coordination between surgical team members. At the same time, that treatment method has to be spread widely to improve treatment of patients with end-stage cirrhosis results.
Efficiency of minimally invasive surgery for liver echinococcosis and its complications
Authors: Azizzoda Z. A. , Kurbonov K. M. , Ruziboyzoda K. R. , Ali-Zade S. G. 
Published: March 2021

Aim. Improving outcomes of diagnosis and treatment of patients with liver echinococcosis and its complications. Materials and methods. A comparative analysis of the results of surgical treatment of liver echinococcosis and its complications with traditional laparotomy access surgery (control group) and minimally invasive interventions (main group) was performed.Results. The study included 300 patients (170 in the control and 130 in the main group). In the main group, 37 (28.4%) cases performed open echinococcectomy from various mini-accesses, and 27 (20.7%) performed twostage operations using minimally invasive technology. Laparoscopic echinococcectomy was performed in 23 (17.7%) patients, laparoscopic pericystectomy 12 (9.2%) and laparoscopic liver resection in 10 (7.7%) patients. The frequency of postoperative complications in the main group was 17.7%, in the control 51.8%, postoperative mortality decreased from 2.3% to 0.8%.Conclusion. Minimally invasive technologies in the surgical treatment of liver echinococcosis show the better immediate results compared to traditional open surgical methods.
АНАЛИЗ ПЛАНИРОВАНИЯ И ОЦЕНКА РЕАЛИЗАЦИИ МУНИЦИПАЛЬНЫХ ПРОГРАММ В СОЦИАЛЬНОЙ СФЕРЕ ГОРОДА ЭЛИСТА
Authors: Курепина Наталья Леонидовна , Баглеева Галина Валерьевна , Асанов Тимур Николаевич 
Published: March 2021

Целью исследования является анализ планирования и реализации муниципальных программ социальной направленности города Элиста.
Методологической основой данного исследования являются общенаучные методы, методы экономического анализа, планирования и моделирования.
Результаты исследования. Проведенные исследования показали, что в муниципальном образовании на протяжении последних лет происходил переход на программно-целевое планирование. Анализ доходной части бюджета, сформированного в соответствии с бюджетной классификацией, показал, что за последние годы налоговые поступления не являются основным источником формирования бюджета города, они составляли только четверть поступлений, более 50% – безвозмездные поступления. Структура расходов утверждается по ведомствам и целевым статьям муниципальных программ. Более 70% расходов направлено на развитие социальной сферы, поэтому при исследовании мы сделали акцент именно на этой статье расходов, наиболее важной для развития муниципалитета. Расходы на образование занимают более половины от общего объема расходов бюджета. Финансовые средства на другие программы социального развития, развитие культуры, физической культуры, спорта, социальную поддержку граждан занимают всего около 8%.
Перспектива исследования. Результаты исследования показали, что при оценке реализации программ нет четкого формирования показателей, позволяющих оценить эффективность исполнения обязательств, необходимо совершенствование методики оценки эффективности реализации муниципальных программ. Совершенствование методических подходов оценки результатов реализации программ является одним из направлений, требующих дальнейшего исследования.
АНАЛИЗ ИСПОЛЬЗОВАНИЯ ГИС В МУНИЦИПАЛЬНЫХ ОБРАЗОВАНИЯХ РОСТОВСКОЙ ОБЛАСТИ
Authors: Ткачева Ольга Александровна , Лукьянченко Елена Павловна , Лукьянченко Елизавета Андреевна 
Published: March 2021

Целью исследования является анализ использования геоинформационных технологий муниципальных образований Ростовской области за период 2018-2020 гг. и предложение мероприятий по совершенствованию использования геоинформационных технологий.
Методологическую базу исследования представляют общенаучные методы логического и статистического анализа, а также элементы системного подхода.
Результаты исследования. Использование геоинформационных систем существенно влияет на разработку мероприятий, принятие решений, а также возможность создания документов нового поколения в сфере управления территориями муниципальных образований. Анализ использования геоинформационных технологий в муниципальных образованиях Ростовской области позволил определить невысокую активность их использования, потребность в повышении цифровой квалификации всех категорий пользователей, отсутствие оперативности актуализации информационных ресурсов ГИС РО. Всё это говорит о необходимости выработки системы мер по активизации использования ГИС в муниципальных образованиях.
Перспективы исследования составляет обоснование необходимости активизации применения геоинформационной системы Ростовской области при разработке мероприятий устойчивого развития территорий муниципальных образований.
НАУКА – «СОТРУДНИЦА» МАТЕРИАЛЬНОЙ ЦИВИЛИЗАЦИИ (РЕАЛЬНОСТЬ И ПЕРСПЕКТИВЫ)
Authors: Матяш Тамара Петровна , Матяш Дмитрий Владимирович 
Published: March 2021

Цель исследования: изучить взаимозависимость типа науки и типа цивилизации; рассмотреть тип цивилизации, соответствующий новоевропейской науке, раскрыть основное содержание этой цивилизации; провести критический анализ апологетики науки в философии Ф. Бэкона; изучить его аргументы в защиту науки перед так называемым «невежеством» теологов и выяснить, почему Бэкон считал, что торжество науки неизбежно таит в себе опасность; рассмотреть философские и богословские критические оценки господствующего убеждения, что наука приносит несомненную пользу человечеству; раскрыть смысл проектов науки, не ориентированной на материальную цивилизацию.
Методологическая база исследования. Эмпирической базой являются труды русских религиозных философов XIX-XX веков, а также богословов VII-го и XIX-го веков. В статье используются сравнительно-исторический метод, метод социально-культурной реконструкции, а также принцип конкретной историчности и критически-рефлексивный анализ текстов.
Результаты исследования. Доказано, что новоевропейская наука содействовала становлению особого типа цивилизации, которую условно можно назвать материальной; раскрыта суть этой цивилизации; показано, что апологет науки Ф. Бэкон не сумел защитить науку от так называемого «невежества теологов», а значит, не сумел обосновать право науки господствовать над природой; реконструированы философские идеи Ф. Бэкона, демонстрирующие, что с одной стороны философ пытался утвердить господство науки, но с другой осознавал, что торжество науки несет угрозу христианской цивилизации, так как утверждает господство человеческого над божественным; рассмотрены критические оценки господствующего около трех веков убеждения в великой пользе науки, проанализированы главные аргументы этой критики, показано, что она является латентной критикой материальной цивилизации; реконструированы проекты науки, не ориентированной на материальную цивилизацию.
Перспективы исследования: продолжить теоретико-методологические исследования проблемы формирования типа цивилизации в ходе обретения наукой гуманистических и метафизических ориентиров и параметров.
GRAVITATIONAL DRIVING: GEODESICS WARPED BY SOLITONS OF ACCELERATION
Authors: Serpa Nilo 
Published: March 2021

<p>Abstract. This article discusses the basic science to be considered as the background for a speculative technology of gravitational propulsion. Generalized functions are applied to the formalism of general relativity to introduce finite dynamic intervals of spacetime to be warped by acceleration solitons, the latter being interpreted as causing geodesic bends in the spacetime continuum.</p><p><strong>Key words</strong>: soliton, propultion, gravitational tail, warp-drive spacetime, spacetime interval.</p><p>=============================================================================</p><p>Dieser Artikel beschreibt die Grundlagenforschung, die als Hintergrund einer spekulativen Technologie des Gravitationsantriebs betrachtet werden soll. Verallgemeinerte Funktionen werden auf den Formalismus der allgemeinen Relativitätstheorie angewendet, um die richtigen Abstände als dynamische Raumzeitintervalle zu definieren. Einsame Beschleunigungswellen werden so interpretiert, dass sie die geodätischen Abweichungen im Raumzeitkontinuum verursachen.</p><p><strong>Schlüsselwörter</strong>: Soliton, Antrieb, Gravitationsschwanz, Warp-Drive-Raumzeit, Raumzeitintervall.</p>
Possibilities of janus kinase inhibitors application in complex treatment of patients with COVID-19
Authors: Saiganov Sergei A. , Mazurov Vadim I. , Melnikov Evgenii S. , Latariia Elgudzha L. 
Published: March 2021

Introduction. More than 30 million cases and more than 970 thousand fatalities from COVID-19 have been registered. The effectiveness of interleukin-6 and interleukin-1 antagonists and janus kinase inhibitors in the treatment of new coronavirus infection is still being analyzed. At present, the emphasis is placed on the introduction into a wide practice of a Russian vaccine named Sputnik V.
Purpose. To compare the effect of complex therapy with baricitinib and dexamethasone on the course of COVID-19 interstitial pneumonia.
Materials and methods. A retrospective analysis of the medical records of 122 people hospitalized at the North-Western State Medical University named after I.I. Mechnikov was carried out. All the patients were divided into three groups: the first one 64 patients who received therapy including baricitinib; the second one 33 patients whose therapy included dexamethasone; the third one 25 patients in the comparison group.
Results. In the first group of patients the lung damage was 25-75% (2-3 degree CT) in 78.1% of the patients, more than 75% in 14.1% of the patients, which was accompanied by severe clinical symptomatology and high laboratory activity. Against the background of the tharapy, positive dynamics of CT was observed in 48.4% of the cases. In the second group of patients the volume of pulmonary tissue damage by CT of 2-3 degrees was observed in 84.9% of the examined patients, clinical and laboratory activity corresponded to the moderate course of the disease. Against the background of the complex therapy, positive dynamics according to CT examination was observed in 18.2% of the cases. In the comparison group, positive dynamics according to CT was observed in 56% of the patients against the background of the therapy. Normalization of clinical and laboratory parameters was observed in all the patients from three study groups on the background of treatment.
Conclusions. In the first group the majority of the patients had he highest number of comorbid pathologies and severe course of COVID-19. Normalization of clinical and laboratory parameters was observed in all the groups of patients. As a result of standard comprehensive therapy, as well as therapy involving baricitinib or dexamethasone, positive dynamics according to CT data was observed in 48.4%, 18.2% and 56% of the patients, respectively.
Confronting Power, Money, and Most Economists
Authors: Cohen Marjorie 
Published: March 2021

The Canadian anti-free trade movement was a genuine ‘movement’ that originated locally in many different places throughout the country and was soon consolidated in a loose coalition at the national level. It was extraordinary for several reasons. First, it brought together a large number of groups that had never worked with each other before and their coalitions were strong and effective. Second, it was a movement based on class issues and was understood that way by its leaders and most of those who participated in it. Third, it democratized thinking and knowledge about economic policy, and this, in turn, meant that many groups and issues that were normally absent from a discussion of macro-economic policy, became central to the debate. Fourth, the anti-free trade movement grew in relation to the specific issues of regions and groups but the critical arguments that developed over time focused on the problems of having market mechanisms dominate both the economic and social spheres. This scrutiny and discussion of the market system itself has not been replicated in debates on any subsequent major policy issue.
Processos criativos e imaginação
Authors: Pinheiro Marina Assis , Breckenfeld Taciana Feitosa de Melo , Lyra Maria da Conceição Diniz Pereira de 
Published: March 2021

O presente artigo discute as dimensões estética, dialógica e, necessariamente, criativa da experiência humana e seu lugar na Psicologia vigente. Para a discussão pretendida, a fotografia e as reflexões de Evgen Bavcar, artista cego e filósofo, são tomadas como metáfora/alegoria para questionar o paradigma cartesiano, naquilo que propõe a separação sujeito-objeto resultando na conceituação artificializante, objetivista e visocêntrica da psique. Nesse sentido, os processos imaginativos e criativos são retomados como funções psicológicas fundamentais à retomada da dimensão estética e dialógica da existência humana.
Ação promovendo a reflexão
Authors: Gavassa Regina Célia Fortuna Broti 
Published: March 2021

Atender as necessidades dos alunos na aquisição de novas aprendizagens em um mundo complexo, globalizado e digital que está em constante mudança demanda repensar abordagens formativas, que prepare os educadores para esse desafio e que reflita na transformação de espaços, mude concepções e relações entre os atores e, consequentemente, possibilite e incentive maior engajamento nos processos de aprendizagem. Este artigo apresenta uma das abordagens adotadas pelo Núcleo de Tecnologias para a Aprendizagem da Secretaria Municipal de Educação de São Paulo, denominado “Seminário e Mostra Ação promovendo a Reflexão”, estruturada pelos princípios pedagógicos de projetos, autonomia, inventividade, colaboração, protagonismo e pensamento reflexivo que se aproximam das premissas da Aprendizagem Criativa.
Palavras-chave: Aprendizagem; Criatividade; Formação; Protagonismo.
CONECTA
Authors: Cota Iva Ribeiro , Paiva Tatiana Vieira dos Santos 
Published: March 2021

Este trabalho apresenta a configuração e as possibilidades do Centro de Oportunidades, Novidades, Experiências, Criações e Tecnologias para a Aprendizagem Criativa - CONECTA, realizado em uma escola pública de educação profissional no interior do Estado da Bahia, por meio do delineamento das práticas desenvolvidas nesse espaço, da ideia que o constitui, das conexões estabelecidas para o seu funcionamento e da metodologia embasada em ações e reconhecimento, por meio de um processo avaliativo que vislumbra novas dinâmicas para as práticas educacionais locais.