bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross‐Cultural Adaptation of the Clinical Frailty Scale for Critically Ill Patients in Spain and Concurrent Validity With FRAIL‐Es
Authors: Arias‐Rivera Susana , Moro‐Tejedor María Nieves , Frutos‐Vivar Fernando , Andreu‐Vázquez Cristina , Thuissard‐Vasallo Israel John , Sánchez‐Sánchez María Mar , Sánchez‐Izquierdo Raquel , Oteiza‐López Lorena , López‐Cuenca Sonia , Checa‐López Marta , Jareño‐Collado Raquel , López‐López Virginia , Sánchez‐Muñoz Eva Isabel , Carrasco Rodríguez‐Rey Luis Fernando , Frade‐Mera María Jesús , Cortés‐Puch Irene , Padilla‐Peinado Rebeca , Huete‐García Alejandro , Lesmes‐González Aledo Amanda , Gordo‐Vidal Federico , Rodríguez‐Merino Ana , Vázquez‐Calatayud Mónica , Vázquez‐Grande Gloria , Mateo Dolores , Herrero‐Hernández Raquel , Raurell‐Torredà Marta 
Published: February 2025

ABSTRACTAimsTo adapt the Clinical Frailty Scale (CFS) into Spanish and assess its concordance with the Spanish version of the FRAIL scale (FRAIL‐Es) in the context of intensive care.DesignValidation study of frailty assessment scales in critically ill patients.MethodsThe study was conducted in two phases. The first phase consisted of translating, culturally adapting, and validating the CFS into Spanish. The second phase consisted of a metric descriptive study to assess the concurrent criterion validity of the adapted CFS with FRAIL‐Es in a cohort of intensive care patients. Both scales were assessed upon admission to intensive care and at 3, 6, 9, and 12 months post‐hospital discharge. Analysis was performed using T‐Student/Mann–Whitney, chi‐squared and Cohen's Kappa tests.ResultsSuccessful adaptation of the CFS with minimal changes was achieved, demonstrating its applicability in the evaluated context. The pilot study indicated that CFS‐Es is easy to assess, but some subjectivity in interpretation was noted. CFS‐Es and FRAIL‐Es were applied to 212 patients, revealing variations in frailty prevalence. The concordance and correlation between the CFS and FRAIL scales are robust. These differences suggest that the choice of scale may impact the identification of frail patients. These results emphasise the importance of considering specific characteristics of each scale when assessing frailty in critically ill patients, providing valuable information for clinical implementation and research in this field.Patient or Public ContributionAssessing frailty upon admission can be helpful in the care of frail patients, allowing the development of specific care plans based on pre‐existing frailty.
Development and Application of the Coverage Path Planning Based on a Biomimetic Robotic Fish
Authors: Liu Jincun , Zhao Jian , Liu Zhenna , Liu Yang , Ren Yinjie , An Dong , Wei Yaoguang 
Published: February 2025

ABSTRACTThis paper addresses the coverage path planning (CPP) and path‐following challenges for an underwater biomimetic robotic fish, aimed at performing water quality monitoring in deep‐sea net cages. First, a novel CPP strategy is proposed to minimize total path length, repetition rate, and turning frequency, thereby enhancing path coverage efficiency and reducing energy consumption. This strategy integrates the Deep Q‐Network (DQN) method, a tailored reward function, and an RRT*‐inspired rewrite mechanism. Second, a high‐performance “LOS‐PID” controller is developed to enable precise path following by the robotic fish. Finally, simulation experiments and field tests with the untethered robotic fish validate the effectiveness of the proposed CPP and path‐following strategies, highlighting their practical applicability in aquaculture management. The proposed algorithm provides valuable insights into optimizing coverage path planning for underwater robotic systems in real‐world scenarios.
Space Economy and Sustainability: A Systematic Review
Authors: Valente Marianna , Caviggioli Federico , Agostini Lara 
Published: February 2025

ABSTRACTThe space economy is booming thanks to the increasing investment of government agencies, private companies, and venture capitalists. From the beginning of the New Space era, the array of actors involved in the development of technologies for extra‐terrestrial activities has increased, as well as the downstream applications that foster innovations on Earth. Space technologies promote growth and prosperity: they pose challenges and opportunities in terms of sustainability from multiple perspectives. In outer space, several issues can hinder launches or the capabilities of observing and collecting data (e.g., presence of debris, regulatory and legal issues), while there is room to improve the technical and economic efficiency of operations; on Earth, technologies developed to support space missions and satellite data provide support to human development and help monitoring climate change. The literature dealing with space sciences is extremely varied, from materials and physics for the launch of probes, to management of missions, or the coordination of international activities. The aim of this study is to investigate whether and how studies in the space economy area addressed the topic of sustainability through a systematic literature review. This article analyses 254 articles along multiple dimensions, including the three pillars of sustainability and the sustainable development goals. The studies are categorized according to their main locus of research (i.e., in Space and on Earth) and then grouped in thematic clusters. In doing so, this article provides an overview of the state of the art, highlights potential gaps, and proposes fruitful avenues for future research.
Effect of reinforcement corrosion and axial load levels on seismic response of non‐ductile reinforced concrete columns
Authors: Amini Safdar Naveed , Rajput Aditya Singh 
Published: February 2025

AbstractThe present study investigated the seismic response of nonseismically designed reinforced concrete (NSRC) columns affected by varying degrees of reinforcement corrosion and subjected to different axial compression ratios (ACR). 3D numerical models representing corroded and noncorroded field‐scale NSRC columns were developed and validated with experimental results. Subsequently, a parametric study was carried out to quantify the combined effect of different ACRs (0.35P0, 0.5P0, 0.6P0, and 0.7P0) and corrosion degrees (0%, 15%, and 30%) on the seismic response of NSRC columns. Critical parameters such as stiffness degradation, hysteresis backbones, ductility ratios, and energy dissipation were evaluated and compared for all the specimens. Results showed that the specimen corresponding to 15% corrosion and 0.7P0 ACR experienced a loss of flexural strength, ductility, and energy dissipation by alarming 55.2%, 60.6%, and 91.3%, respectively. The losses were even higher for specimens subjected to a 30% corrosion level. The quantification of catastrophic performance degradation in corrosion‐affected NSRC columns provides crucial insights for designing effective retrofitting strategies to enhance their seismic resilience.
The application of duckweed (Lemna minor) and freshwater mussels (Anodonta cygnea) as living biofilters integrating with a filtration system to maintain water quality in juvenile trout (Oncorhynchus mykiss) rearing using the small scale RAS system
Authors: Azhar Muhammad Hanif , Memiş Devrim 
Published: February 2025

AbstractIncreasing nutrient concentrations in fish culture systems over time can reduce water quality. However, the nutrient increase can be remediated by pairing organisms at lower trophic levels with a mechanical filtration system to improve nutrient removal efficiency and water quality for fish culture. This research uses the RAS system to determine the performance of integrating living organisms as biofilters in rearing juvenile rainbow trout (Oncorhynchus mykiss) for 56 days. Duckweed (Lemna minor) was added to replicate tanks at three treatment levels: T1 (100 g wet weight and 20% area coverage), T2 (200 g wet weight and 40% area coverage), and T3 (300g wet weight and 60% area coverage). The duckweed in each treatment tank was supplemented with 20 freshwater mussels (Anodonta cygnea) with an average body weight of 56 ± 1.0 g. Physical and chemical water quality parameters were measured in fish tanks and all ponds in the RAS system. Fish from the rearing tanks were weighed every two weeks. Duckweed biomass was measured weekly; the mussels were weighed at the beginning and end of the study, and the mussels were measured at the beginning and end of the rearing period. The fish was partially harvested every two weeks to maintain constant fish biomass. Using duckweed (L. minor) with different biomass weights and areal coverage, coupled with the freshwater mussels (A. cygnea) as living biofilters, had a significant effect (P < 0.05) on water quality parameters. Ammonium (NH4), nitrite (NO2), and nitrate (NO3) concentrations decreased throughout the study. During the study period, juvenile trout experienced growth with an SGR of 2.62–2.72%/gram with a survival rate of 100%. Partial harvesting during the rearing period positively impacted the average body weight of fish growth and duckweed biomass. The best duckweed growth performance was found in treatment T1 (cover area 20% with wet weight 100 g) with a productivity of 9.4 (g/m2/day).Practitioner Points
Twenty percent duckweed coverage with freshwater mussels achieves optimal nutrient removal in RAS systems, improving water quality efficiently and growth better than other treatments.
Combined biofilters (duckweed‐mussel) and filtration units reduce operational costs while maintaining high fish survival rates in RAS systems.
Integration of living biofilters provides sustainable water treatment without chemical additives, suitable for small‐scale aquaculture operations.
The Full Electroweak Interaction: An Autonomous Account
Authors: Gracia-Bondía José M. , Rehren Karl-Henning , Várilly Joseph C. 
Published: February 2025

Abstract
The precise renormalizable interactions in the bosonic sector of electroweak theory are intrinsically determined in the autonomous approach to perturbation theory. This proceeds directly on the Hilbert–Fock space built on the Wigner unirreps of the physical particles, with their given masses: those of three massive vector bosons, a photon, and a massive scalar (the “higgs”). Neither “gauge choices” nor an unobservable “mechanism of spontaneous symmetry breaking” is invoked. Instead, to proceed on Hilbert space requires using string-localized fields to describe the vector bosons. In such a framework, the condition of string independence of the

$${\mathbb {S}}$$

S

-matrix yields consistency constraints on the coupling coefficients, the essentially unique outcome being the experimentally known one. The analysis can be largely carried out for other configurations of massive and massless vector bosons, paving the way towards consideration of consistent mass patterns beyond those of the electroweak theory.
Spatiotemporal Diffusion Variability of Injection-Induced Seismicity in Enhanced Geothermal Systems
Authors: Michas Georgios 
Published: February 2025

Abstract
Injection-induced seismicity represents a major challenge for the development of Enhanced Geothermal Systems (EGS). To effectively mitigate the associated seismic hazard, a better understanding of the spatiotemporal evolution of induced seismicity and its efficient modeling are required. Towards that end, a stochastic framework within the continuous time random walk (CTRW) theory is used to make inferences regarding the diffusion properties of injection-induced seismicity in three cases of hydraulic stimulations in EGS. The analysis of seismicity within the CTRW context indicates multi-scaling variations in the waiting times distributions and in the evolution of the mean squared distance of seismicity with time, both associated with the co- and post-injection periods, respectively. During fluid-injections, an almost Poissonian waiting times distribution is followed by broad distributions during post-injection, enhancing long-term clustering effects and inter-earthquake interactions. At the same time, the rate of triggered earthquake diffusion drastically drops during the post-injection period for all the studied cases. Such properties may have implications on the main driving mechanisms of injection-induced seismicity in EGS, highlighting the transition from a dominant pressure-driven triggering mechanism during fluid-injections, to a mixed mechanism after termination of injections, where stress transfer effects and inter-earthquake interactions become more important.
Wirkungen der Beteiligung und Partizipation von Bürger:innen in Erkenntnisprozessen der integrierten kommunalen Gesundheitsförderung. Ein systematischer Scoping-Review
Authors: Hartung Susanne , Houwaart Stefanie , von Rüden Ursula , Schaefer Ina 
Published: February 2025

Zusammenfassung

Hintergrund
Beteiligung und Partizipation von Bürger:innen sind anerkannte Anforderungen in verschiedenen Handlungsfeldern von Public Health. Mittels eines Scoping-Reviews sollen die Wirkungen von Beteiligung und Partizipation von Bürger:innen in Erkenntnisprozessen der integrierten kommunalen Gesundheitsförderung systematisch untersucht und aufbereitet werden.

Methoden
Der anhand des PRISMA-Frameworks durchgeführte Scoping-Review wurde durch eine systematische Handrecherche ergänzt. Basierend auf dem Modell der Partizipativen Gesundheitsforschung und dem PHINEO-Wirkungsmodell wurde für die Aufbereitung der Ergebnisse ein Analyseraster entwickelt.

Ergebnisse
Insgesamt wurden 30 Publikationen aus 6 Teilprojekten von Forschungsverbünden (darunter auch forschungsverbundübergreifende Publikationen) sowie aus 6 eigenständigen Projekten in die Auswertung eingeschlossen. Wirkungen wurden hauptsächlich für positive Veränderungen hinsichtlich des Bewusstseins und der Fähigkeiten der direkt beteiligten und partizipierenden Bürger:innen und Projektpartner:innen berichtet sowie darüber hinaus in geringerem Umfang für nicht direkt beteiligte Bürger:innen und Stakeholder. Verhältnisänderungen leiteten sich aus den Veränderungen im Bewusstsein und Handeln der Stakeholder ab, die in den Projekten beteiligt waren.

Diskussion
Die Wirkungen von Beteiligung und Partizipation von Bürger:innen in Erkenntnisprozessen der kommunalen Gesundheitsförderung sind vielfältig und betreffen nicht nur die Zielgruppe des jeweiligen (Teil‑)Projektes. Zugleich gibt es nur wenige Wirkungsbeschreibungen, die über die Ebene der direkt Beteiligten hinausreichen. Für die systematische Implementierung, Evaluation und Veröffentlichung partizipativer Erkenntnisprozesse sind adäquate Förderung und Strukturen nötig.
Whither the price of coffee? An analysis of trends and shocks since the coffee crisis
Authors: Ghoshray Atanu , Mise Emi 
Published: February 2025

Abstract
This short paper examines two potent issues that affect coffee producers worldwide. First, we estimate whether the real price of coffee received by producers are declining over time, making the coffee growers worse off. Secondly, we estimate how long it takes for exogenous shocks to dissipate, so that farmers can be better informed to manage volatile coffee prices. We find no evidence of any prevalent declining trend, and the time taken for a price shock to dissipate by half can vary widely from 5 to 18 months for individual coffee prices.
Detection of PRKAR1A gene mutations in sporadic cardiac myxomas: a study of 24 cases
Authors: Bekers Elise , van Bladel Diede A. G. , Berendsen Madeleine R. , Eijkelenboom Astrid , van Krieken J. Han J. M. , Ooft Marc , Ruijter Emiel , Verhagen Ad , Flucke Uta E. , Scheijen Blanca 
Published: February 2025

Abstract
The benign neoplasm cardiac myxoma represents one of the hallmarks of Carney complex (CNC), a familial multiple neoplasia syndrome. About 80% of the index cases have germline mutations in PRKAR1A encoding the RIα regulatory subunit of cAMP-dependent protein kinase A (PKA). However, the role of PRKAR1A gene mutations in the pathogenesis of non-CNC-associated sporadic cardiac myxoma is less well established. Here, we investigated the presence of PRKAR1A gene variants in a cohort of 24 sporadic cardiac myxomas using targeted next-generation sequencing. Our study shows that 14 out of 24 cases (58%) harbor PRKAR1A gene mutations, represented mostly by frameshift, nonsense, and splice site mutations (together 84%), leading to a premature stop codon predicted to be degraded via non-sense mediated mRNA decay. The other 16% of PRKAR1A genetic alterations involved missense mutations, often located in important functional domains of the regulatory subunit RIα. Notably, 64% (n = 9/14) of the cases harbored more than one PRKAR1A gene variant, suggesting compound heterozygous mutations either in cis or trans. In conclusion, PRKAR1A gene mutations associated with loss of RIα function leading to increased PKA activity were observed in ~ 60% of sporadic cardiac myxomas, strongly supporting an essential role for PKA in mediating formation of cardiac myxoma.
Update on esophageal function, acid and non-acid reflux after one-anastomosis gastric bypass (OAGB): high-resolution manometry, impedance-24-h pH-metry, and gastroscopy in a prospective mid-term study
Authors: Felsenreich D. M. , Vock N. , Zach M. L. , Kristo I. , Jedamzik J. , Bichler C. , Eichelter J. , Mairinger M. , Gensthaler L. , Nixdorf L. , Richwien P. , Pedarnig L. , Langer F. B. , Prager G. 
Published: February 2025

Abstract

Background
One-anastomosis gastric bypass (OAGB) is the third most common metabolic/bariatric procedure worldwide. A point for discussion regarding OAGB is acid and non-acid reflux in mid- and long-term follow-up. The aim of this study was to objectively evaluate reflux and esophagus motility by comparing pre- and postoperative results of 24-h pH-metry, high-resolution manometry (HRM), and gastroscopy.

Setting
Cross-sectional study and university hospital based.

Methods
This study includes primary OAGB patients operated at the Medical University of Vienna before 31st December 2022. After a mean follow-up of 4.1 ± 2.9 years, the preoperative examinations were repeated. Additionally, history of weight, remission of obesity-related complications (ORC), and quality of life (QOL) were evaluated.

Results
A total of 50 patients were included in this study and went through all examinations. Preoperative weight was 125.5 ± 21.0 kg with a BMI of 44.6 ± 5.4 kg/m2 and total weight loss after 4.1 ± 2.9 years was 37.1 ± 8.1%. Remission of ORC and QOL outcomes was successful in all categories. Gastroscopy showed anastomositis, esophagitis, Barrett’s esophagus, and bile in the pouch in 38.0%, 34.0%, 6.0%, and 48.0%, respectively. In HRM, the postoperative lower esophageal sphincter pressure was 29.6 ± 15.1 mmHg (unchanged to preoperative). The total number of refluxes was equal to preoperative, whereas decreased acid refluxes were replaced by increasing non-acid refluxes. Impedance-24-h pH-metry showed that acid exposure time of the esophagus and DeMeester score decreased significantly to 1.6 ± 1.4% (p = 0.001) and 10.3 ± 9.6 (p = 0.046).

Conclusion
This study has shown decreased rates of acid reflux and increased rates of non-acid reflux after a mid-term outcome of primary OAGB patients. Gastroscopy showed significant signs of chronic reflux exposure of the anastomosis, the pouch, and the distal esophagus, even in asymptomatic patients. General follow-up visits in patients after OAGB should be considered.

Graphical abstract
Partial Groupoid Actions on Smooth Manifolds
Authors: Marín Víctor , Pinedo Héctor , Rodríguez José L. Vilca 
Published: February 2025

Abstract
Given a smooth partial action

$$\alpha $$

α

of a Lie groupoid G on a smooth manifold M, we provide necessary and sufficient conditions for

$$\alpha $$

α

to be globalizable with smooth globalization. As an application, we provide results on the differentiable structure of orbit and stabilizer spaces induced by

$$\alpha ,$$

α
,

which leads to other criteria for its globalization in terms of its orbit maps in the case that

$$\alpha $$

α

is free and transitive. Further, under the assumption that

$$\alpha $$

α

is free and proper, we prove that there exists exactly one differentiable structure on the quotient structure of the orbit equivalence space M/G such that the quotient map

$$\pi :M\rightarrow M/G$$

π
:
M
→
M
/
G

is a submersion.
Development and application of predictive clinical biomarkers for low back pain care: recommendations from the ISSLS phenotype/precision spine focus group
Authors: Hodges Paul W. , Sowa Gwendolyn , O’Neill Conor , Vo Nam , Foster Nadine , Samartzis Dino , Lotz Jeffrey 
Published: February 2025

Abstract
Predictive biomarkers (or moderators of treatment) are features, or more likely feature clusters, that discriminate individuals who are more likely to experience a favourable or unfavourable effect from a specific treatment. Utilization of validated predictive biomarkers for chronic low back pain (CLBP) treatments is a plausible strategy to guide patients more rapidly to effective treatments thereby reducing wastage of finite healthcare funds on treatments that are ineffective (or potentially harmful). Yet, few predictive biomarkers have been successfully validated in clinical studies. This paper summarizes work by the Phenotype/Precision Spine Focus Group of the International Society for the Study of the Lumbar Spine that addressed: (1) relevant definitions for terminology; (2) advantages and disadvantages of different research approaches for the specification of predictive biomarkers; (3) methods for assessment of clinical validity; (4) approaches for their implementation; (5) barriers to predictive biomarker identification; and (6) a prioritised list of recommendations for the development and refinement of predictive biomarkers for CLBP. Key recommendations include the harmonisation of data collection, data sharing, integration of theoretical models, development of new treatments, and health economic analyses to inform cost-benefit of assessments and the application of matched treatments. The complexity of CLBP demands large datasets to derive meaningful progress. This will require coordinated and substantive collaboration involving multiple disciplines and across the research spectrum from the basic sciences to clinical applications.
An immunohistochemical approach to cell wall polysaccharide specialization in maritime pine (Pinus pinaster) needles
Authors: Michavila Santiago , Encina Antonio , De la Rubia Alfonso G. , Centeno María Luz , García-Angulo Penélope 
Published: February 2025

Abstract
Pine needles are specialized leaves bearing distinctive anatomical features whose function is to minimize water loss. At the molecular level, needle specialization is expected to lead to heterogeneity in cell wall (CW) composition. By immunohistochemical analysis of CW epitopes in maritime pine (Pinus pinaster) needles, we described the variability of CW composition in all tissues, discussing its possible relationship with the cell function. Cells specialized in water transport, tracheids, transfusion tracheids, and endodermis, together with epi/hypodermal and stomatal cells, had similar CW composition, where epitopes for pectins (homogalacturonan and rhamnogalacturonan-I), xyloglucan, and heteroxylans were abundant. Heteroxylans differ between the dermis, enriched in arabinoxylan, and endodermis, enriched in glucuronoxylan. Xylem CWs were very rich in (arabino)xylans and homogalacturonan and distinctively lacked immunolabelling for rhamnogalacturonan-I. CWs from phloem, transfusion phloem, mesophyll, and resin ducts were enriched in homogalacturonan, rhamnogalacturonan-I, and xyloglucan, showing a low content for heteroxylan epitopes. Arabinogalactan proteins were detected in mesophyll and in cells specialized in solute transport such as phloem, duct sheath, and guard cells. These results show that tissues with similar functions have similar polysaccharide composition, shedding light on the role of CW components through different tissues.