bluuebunny/crossref_metadata_2025_split huggingface dataset:
Breastfeeding Promotion and Nursing Care for Infants with Cleft Palate and/or Cleft Lip in Northeastern Craniofacial Center, Thailand
Authors: Namchaitaharn Suntaree , Pimpiwan Naphatchamon , Saengnipanthkul Suchaorn 
Published: October 2021

Background:The common feeding problems in infants with Cleft Palate (CP) and/or Cleft Lip and Palate (CLP) are the inability to suck and swallow breastmilk. Difficulties in feeding may compromise normal growth and disrupt the bonding process.Objective:To evaluate the treatment and breastfeeding rate in infants with CP and CLP.Methods:A retrospective study of infants with CP and CLP who were admitted to the postpartum ward between July 2017 and June 2019 was conducted. Demographic data, type of feeding, nursing activities, and duration of breastfeeding after discharge were collected.Results:A total of 35 infants were included in the study. Twenty-seven cases were non-syndromic complete CLP (77.2%). On admission only 15 infants (42.8%) received breastmilk and alternative feeding techniques were applied for 26 (74.3%) infants. Breastfeeding promotion and nursing care were provided to mothers and infants by an interdisciplinary team at the Craniofacial Center. The median Length of Stay (LOS) was 8 days (range 5-9 days) and infants born at the affiliated hospital (inborn) had a significantly shorter LOS compared to infants referred from other health centers (p=0.019). None of the inborn groups received infant formula. The breastfeeding rate in all groups was 100% at discharge. Exclusive breastfeeding rates at 2-, 4-, and 6-months follow-up were 82.8%, 42.8%, and 31.4%, respectively.Conclusion:Breastfeeding promotion, education, and nursing care from an interdisciplinary team resulted in an improved ability of mothers to breastfeed infants with CLP, particularly in non-syndromic CLP. The exclusive breastfeeding rate after 6-months in this study was higher than in previous studies.
Impactos socioambientais nas construções de barragens hidrelétricas
Authors: Renata Freitas Fontes Alessandra , Severo Giudice Dante 
Published: October 2021

O presente artigo possui como objetivo geral definir e traçar análise sob a implantação de barragens hidrelétricas no Brasil. O estudo sobre os impactos causados por tais construções é realizado por intermédio do prisma econômico, social e ambiental. Para o estudo, parte-se da vertente jurídico-sociológica e utiliza-se a metodologia de pesquisa teórica, a partir de uma revisão bibliográfica pautada em documentos que evidenciam o tema exposto. Como resultado da pesquisa, infere-se que existe na construção de tais empreendimentos uma assimetria de poder, que origina uma apropriação social sobre os conflitos socioambientais, na medida em que a utilização dos espaços ambientais ocorre em detrimento do uso que outros segmentos sociais fazem do território. Dessa maneira, constata-se que barragens hidrelétricas são geradoras de injustiça ambiental, visto que são construídas e implementadas com a finalidade precípua de beneficiar determinados setores econômicos, em prol de direitos fundamentais da comunidade direta e indiretamente afetada.
Esquistossomose mansônica: uma análise do perfil epidemiológico na região sudeste
Authors: Barreto Costa João Victor , Marques da Silva Filho José 
Published: October 2021

Este estudo tem o objetivo de traçar o perfil epidemiológico da esquistossomose mansônica (EM) na região Sudeste do Brasil entre os anos de 2013 a 2017. É um tipo de estudo descritivo de tendência temporal, em que foram utilizados dados disponíveis nos registros de notificação do Departamento de Informática do Sistema Único de Saúde (DATASUS), considerando o período de 2013 a 2017. O cálculo da incidência foi obtido através da estimativa populacional projetada pelo Instituto Brasileiro de Geografia e Estatística - IBGE. Os dados coletados foram processados pelo Excel 2016. Durante o período foram notificados 21.464 casos da doença no Sudeste brasileiro, tendo Minas Gerais (73,25%) e São Paulo (15,52%) os maiores valores absolutos de contaminação. Percebe-se que a incidência na região diminuiu de 6,03 para 3,35 casos/ano. A maior frequência dos casos envolveu os adultos que estão entre a faixa etária dos 20 aos 39 anos, sendo o sexo masculino (35,5%) o mais acometido. Além disso, a EM teve uma maior predominância na zona urbana (72,7%). Assim, os casos notificados e a incidência da doença diminuíram na região estudada. Conclui-se que estratégias preventivas e educacionais necessitam ser adotadas, com o intuito de reduzir a incidência de EM na área endêmica da região Sudeste.
Group Membership or Identity?
Authors: Teschl Miriam 
Published: October 2021

As part of an article symposium on Partha Dasgupta and Sanjeev Goyal’s “Narrow Identities” (2019, Journal of Institutional and Theoretical Economics), Miriam Teschl reflects on the distinctive concept of identity liberal cosmopolitans have and how it may or may not be captured in economic models of identity choice.
Las homilías Adversus Iudaeos de Juan Crisóstomo: temas y estrategias argumentativas polémicas
Authors: Simonassi Lyon Andrea 
Published: October 2021

Mientras fue presbítero de Antioquía entre 386 y 398 –año en que fue nombrado Patriarca de Constantinopla–, Juan Crisóstomo, representante del cristianismo niceno, tuvo una prolífica carrera como predicador en las iglesias más importantes de la ciudad. Fue conocido como “boca de oro” por sus dotes en retórica y son muchas las obras homiléticas que se adjudican a su período antioqueno, entre las que podemos citar su serie conocida como Adversus Iudaeos. Pronunciada entre los años 386 y 387, tiene como objeto atacar a aquellos cristianos que participan de festividades judías y asisten a la sinagoga. Pero no son sólo ellos los que sufrirán el embate del presbítero: a lo largo de su serie, vemos cómo arremete contra los judíos, la Sinagoga, la Ley mosaica y las fiestas judías. El presente artículo se propone rastrear y discutir los epítetos y críticas pronunciados por Crisóstomo en las homilías Adversus Iudaeos en contra de los judíos y sus principales instituciones y festividades, así como contra aquellos miembros de su congregación que compartían, asistían a y participaban de sus fiestas, y recurrían a los “especialistas en lo sagrado” judíos para obtener curas o solucionar problemas.
Modelling Anisotropic Phenomena of Friction of Deep-Drawing Quality Steel Sheets Using Artificial Neural Networks
Authors: Trzepieciński Tomasz , Lemu Hirpa G. , Chodoła Łukasz , Ficek Daniel , Szczęsny Ireneusz 
Published: October 2021

Abstract
This paper presents a method of determining the coefficient of friction in metal forming using multilayer perceptron based on experimental data obtained from the pin-on-disk tribometer. As test material, deep-drawing quality DC01, DC03 and DC05 steel sheets were used. The experimental results show that the coefficient of friction depends on the measured angle from the rolling direction and corresponds to the surface topography. The number of input variables of the artificial neural network was optimized using genetic algorithms. In this process, surface parameters of the sheet, sheet material parameters, friction conditions and pressure force were used as input parameters to train the artificial neural network. Some of the obtained results have pointed out that genetic algorithm can successfully be applied to optimize the training set. The trained multilayer perceptron predicted the value of the friction coefficient for the DC04 sheet. It was found that the tested steel sheet exhibits anisotropic tribological properties. The highest values of the coefficient of friction under dry friction conditions were registered for sheet DC05, which had the lowest value of the yield stress. Prediction results of coefficient of friction by multilayer perceptron were in qualitative and quantitative agreement with the experimental ones.
Adenosquamous and squamous cell carcinoma of the pancreas: two histopathological variants of ductal adenocarcinoma
Authors: Szekely Tiberiu-Bogdan , Toganel Cornelia , Kadar Zoltan , Sava Alexandra Daniela , Bara Tivadar , Roman Daniela , Gurzu Simona 
Published: October 2021

Abstract

Introduction: Primary squamous cell carcinoma (SCC) and adenosquamous carcinoma of the pancreas are rare malignancies for which diagnostic and treatment strategy are challenging. In this paper we present a literature review of these tumors based on two case reports.

Case presentation: In the first case, a 55-year-old male presented with an inoperable pancreatic head/body junction tumor. Endoscopic ultrasound-guided fine needle aspiration was practiced, and histopathological examination revealed a squamous cell carcinoma of the pancreas. After exclusion of any another tumor, the diagnosis of cT4N0M0-staged primary pancreatic SCC was made. The patient is under treatment with gemcitabine and oxaliplatin. The second case is represented by a 73-year-old patient in which imagistic examinations highlighted a cystic mass of the pancreatic body. Following coporeo-caudal splenic-pancreatectomy and histopathological-proved diagnosis of adenosquamous carcinoma, the patient started chemotherapy but died at 11 months after surgery. Both tumor components displayed positivity for markers which prove ductal (cytokeratin19, maspin) and squamous differentiation (p63, cytokeratin5/6) same as vimentin, as indicator of epithelial mesenchymal transition (EMT).

Conclusions: SCC and adenosquamous carcinoma of the pancreas are aggressive malignancies which prognosis remains highly reserved. These tumors might be variants of ductal adenocarcinomas which are dedifferentiated through EMT phenomenon.
Vascular injury in macroscopically normal skin of patients with severe COVID-19 infection: clinical-pathologic correlations
Authors: Coșarcă Mircea-Catălin , Mureșan Vasile Adrian , Horvath Emoke , Russu Eliza , Szederjesi Janos , Keresztes Matild 
Published: October 2021

Abstract

Objectives: Taking into account that the documentation of the histopathological features in severe disease caused by SARS-CoV-2 has been scarce due to the avoidance of performing autopsies, the aim of the study was to detect the microscopic changes associated with severe COVID-19 infection in normal-appearing skin, without prominent dermatologic signs of a generalized microvascular thrombotic disorder, in accordance with the clinical evolution of disease.

Methods: In this morphological and immunohistochemical study we included cutaneous biopsy samples from 12 symptomatic patients with severe and critical type SARS-CoV-2 infection (with the admission date between February and June 2020), treated in the Intensive Therapy Unit Care of Emergency County Hospital Targu-Mures, Romania.

Results: The average age of our patients was 65.18 ± 14.21 years (range 41 to 83), and 66.67% of the patients were male. The histological and immunohistochemical assessment of cutaneous biopsies: in 4 cases the histological examination revealed small fibrin thrombi in deep-seated venules and small veins of subcuticular adipose tissue, and also 4 cutaneous biopsies showed occlusive vascular thrombosis in association with massive perivascular inflammatory infiltrate destroying and compromising the integrity of the vessel wall. The immunohistochemical examination of the composition of perivascular inflammatory infiltrate showed a predominance of CD3 positive lymphocytes, admixed with CD68 positive Mo/ MF, some of them activated with FXIII expression. In the perivascular infiltrate, the presence of granulocytes and B lymphocytes was not characteristic.

Conclusion: According to our observations, in severe COVID-19, the cutaneous tissue is involved even in the absence of clinically obvious changes. Due to the relatively easy accessibility of skin samples, these could be applied to determine the severity of the patient’s clinical status, and to predict the necessity for anti-complement or anticoagulant treatments in the early stages of a severe SARS-CoV-2 infection.
Thyroglossal duct cyst papillary thyroid cancer – the state of the art
Authors: Dabrowska Anna Maria , Dudka Jaroslaw 
Published: October 2021

Abstract
Thyroglossal duct cyst is one of the most common congenital malformations in the neck area. The majority of cysts turn out to be benign tumors, however, 0.7-1.5 % of the remnants develop into carcinoma, with papillary thyroid cancer being the most frequent malignant neoplasm. The origin of the cancer has not been clearly established so far. Typically, thyroglossal duct cyst cancer is an enlarging flexible midline or slightly lateral neck mass, most often without other worrisome symptoms. The proper diagnosis can be difficult due to the rare prevalence of thyroglossal duct cyst papillary thyroid carcinoma, as well as a lack of strongly typical features distinguishing benign and malignant lesions before surgery. Thus, diagnosis is usually made postoperatively just after histopathological examination of a resected cyst. However, there are diagnostic procedures that should be considered before the surgery that may be helpful in making a proper diagnosis. These include fine-needle aspiration biopsy, computed tomography or magnetic resonance imaging. Moreover, there are some characteristics revealed through clinical and ultrasound examination that may suggest the presence of such cancer. While the Sistrunk procedure is often considered adequate, currently, there is no clear consensus about concurrent thyroidectomy or radioiodine therapy. In the article, we sum up the preoperative suggestive factors of cancer, as well as the proposed indications that can be helpful in deciding on the extent of surgery and further management.
Urinary iodine as an important indicator for preeclampsia: a Polish perspective
Authors: Gajewska Katarzyna , Laskowska Marzena , Blazewicz Anna 
Published: October 2021

Abstract
Preeclampsia (PE) is one of the leading causes of perinatal and maternal morbidity. Although subclinical hypothyroidism in pregnancy is one of the established risk factors for PE, the link between iodine deficiency and PE is not fully understood. The aim of our study was to assess urinary iodine concentration (UIC), serum thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), and free thyroxine (fT4) levels in Polish women with PE (PE group, n=78) compared with healthy non-pregnant women (CNP group, n=30), and healthy pregnant women (CP group, n=46). The UIC was determined by inductively coupled plasma mass spectrometry (ICP-MS). Both the mean UIC of 144.6±36.4 μg/L in the CP group and the mean of 125.8±33.6 μg/L in the PE group, respectively, were lower compared to non-pregnant women (149.8±28.8 μg/L), and the difference between the PE and CNP groups was statistically significant. TSH values were the highest in the PE group, while the lowest average level was for the CNP group. The fT3 and fT4 values in the PE group were significantly lower compared to the CNP and CP groups. Despite iodine supplementation during pregnancy, the UIC was lower compared to non-pregnant women, while in women with PE it was at a significantly lower level. To reduce the incidence of possible health complications, proper iodine supplementation and monitoring of the UIC is recommended for pregnant women suffering from PE or at risk of developing PE.
Comparative efficacy of empagliflozin versus placebo in the treatment of type 1 diabetes mellitus: a meta-analysis of randomized controlled trials
Authors: Gillani Syed Wasif , Azhar Anam , Gulam Shabaz Mohiuddin , Gebreigziabher Fithawit Bahran , Rathore Hassaan Anwer 
Published: October 2021

Abstract
The objective of this meta-analysis study was to evaluate the comparative efficacy of empagliflozin (25 mg) with placebo in the treatment and management of type 1 diabetes mellitus. This study is a meta-analysis, so an ethical statement is not required. Different databases and individual journal websites like SCOPUS, Science direct, Cochrane review library etc. were used. The articles were evaluated based on the search and eligibility criteria. A total of five RCTs were incorporated in this meta-analysis. These studies contained a total of 1058 patients, including 526 patients with placebo (or control-treated patients), and 532 patients with empagliflozin (25 mg) treated combination. The mean follow-up time ranged from 7 days to 6 months. Overall, mean reduction in placebo was -0.50% and empa-treated was -0.85%, while the pooled WMD was 3.82 995% CI 1.20 – 5.88, p=0.0001). Regarding urinary glucose excretion, that the pooled WMD was 6.67 (95% CI 4.87-10.14, p=0.001) indicated a significant increase in empa-arm compared to placebo. No heterogeneity was found (I2 – 15.03%). This meta-analysis underlined the therapeutic benefit of empagliflozin as an adjunctive therapy for patients with type 1 diabetes.
Casirivimab and imdevimab as investigational monoclonal antibodies for COVID-19 patients – review of the literature
Authors: Reka Gabriela , Pawlak Angelika , Machowiec Piotr , Maksymowicz Marcela , Piecewicz-Szczesna Halina 
Published: October 2021

Abstract
Casirivimab and imdevimab (REGN-COV-2) are investigational monoclonal antibodies approved in November 2020 by the Food and Drug Administration for emergency use in mild and moderate COVID-19. These two noncompeting human IgG1 monoclonal antibodies can target the receptor-binding domain of the spike protein of SARSCoV-2, prevent its entry into human cells, and reduce viral load. The antibodies can be administered intravenously for mild-to-moderate COVID-19 patients who do not require hospitalization and supplemental oxygen. The purpose of the study is to review the latest available data on COVID-19 treatment using casirivimab and imdevimab. According to recent preclinical studies, the antibody cocktail presents optimal antiviral strength and has the potential to minimize the chances of the virus escaping. It was shown in animal studies that the cocktail reduces the pathological consequences caused by viruses, decreases the number of viruses in the respiratory system, and reduces lung titers and pneumonia symptoms. Casirivimab and imdevimab as a cocktail also prevents the rapid appearance of treatment-resistant mutants. In the clinical trial, REGN-COV-2 decreased viral load, particularly in patients with a non-initiated immune response (serum antibody-negative) and with high viral load at baseline. The adverse effects were comparable in the combined REGN-COV2 dose groups (2.4 g and 8.0 g), as well as in the placebo group. The cocktail caused few and mainly low-grade toxic effects. Casirivimab and imdevimab seem to be effective and safe antiviral therapy for nonhospitalized patients with COVID-19. Further observations and research are extremely necessary to assess the efficacy, security and indications in a wider group of patients.
Pre-Hispanic Nahua Slavery
Authors: Vyšný Peter 
Published: October 2021

Abstract
The article deals with pre-Hispanic Nahua slavery. Based upon an examination of Nahua perception of slavery/slaves, Nahua forms of slavery (apart from the slaves destined for sacrifice there were slaves destined for work) and the social and legal position of Nahua slaves (destined for work) the author concludes that the Nahua institution traditionally called “slavery“ is different from its counterparts known from the history of Occident. Except for slaves destined for sacrifice to the gods which are discussed only briefly in the article, the Nahua slaves (i.e. the slaves destined for work) had a certain degree of personal freedom and certain rights. Becoming a slave at birth was possible only exceptionally and the enslavement of persons was in many cases (even if not in all cases) only temporary. The treatment of Nahua slaves – compared to the living conditions of their counterparts in many other world cultures – was significantly better, more humane. This can be seen from the fact that the master was entitled only to his/her slave’s labor and not to slave’s life, health, family members or property, as well as from the fact that the slave could obtain freedom in many ways, not only by the manumission made by his/her master. Although slaves were considered a kind of both physically and mentally “less perfect“ individuals who were “dirtied“, that is, morally tainted and dishonored by their enslavement and its reasons (mainly a delinquent behavior, i.e. non-payment of debts or perpetration of certain crimes), they were not systematically excluded from the wider society formed by free persons and they lived with their families in their houses and neighborhoods.
Analysis of species floristics within the oak forests of Guerrouche (Jijel, Algeria)
Authors: Bounar Rabah , Charmat Sabah , Amara Djilani Ghemmam , Adjabi Amina 
Published: October 2021

Abstract
The Guerrouche forest is home to a fairly important flora heritage which offers this massif a forest cover by the presence of quite remarkable forest stands, from a floristic point of view by the presence of natural vegetation characterized by a diverse flora. This study aims to quantify the floristic diversity of the vegetation associated with the three main tree species (zeen oak, cork oak and afares oak) that inhabit the Guerrouche forest on the basis of distributed floristic surveys, according to a sampling strategy. stratified and systematic, which took into account the species present in each type of tree stand. The floristic surveys thus carried out, numbering 55, made it possible to establish a list of a floristic list made up of 172 species, which belonged to 69 genera and 45 botanical families. Of these, 42 were endemic species, including 4 specific to the study area. The number of rare and very rare species was 70 taxa. The study also revealed the clear degradation of the genus Erica of this ecosystem. Analysis of the overall chorological spectrum showed a dominance of Mediterranean species (209 species), with a dominance (82.3%) of species that were therophyte species. The forest stands of the genus Quercus inhabiting the Guerrouche massif must be supported by the authorities to preserve and conserve this forest heritage against fires, illegal logging, etc. The results of this study will be the subject of development actions and rational management of these natural forest ecosystems.
In Vitro Inhibitory Activity of Cell-Free Supernatants of Lactobacillus Spp. and Bacillus Spp. Against Fusarium graminearum
Authors: Harčárová M. , Čonková E. , Naď P. , Váczi P. , Proškovcová M. 
Published: October 2021

Abstract
In this study, the antifungal activity of cell-free supernatant (CFS) of Lactobacillus spp. (Lactobacillus plantarum CCM 1904; L81, Lactobacillus fermentum; 2I3, Lactobacilus reuteri; 2/6, L26;) and Bacillus spp. (Bacillus subtilis CCM 2794, Bacillus licheniformis CCM 2206) against two strains of Fusarium graminearum CCM F-683 and Fusarium graminearum CCM 8244 were investigated in vitro. All tested CFS of Lactobacillus spp. were able to inhibit the growth of both strains of Fusarium graminearum. The highest inhibitory effect (IE) (56.5 %) against F. graminearum CCM F-683 was observed for CFS Lactobacillus fermentum (2I3) at the minimum inhibitory concentration (MIC) (2.25 ± 0.56 mg.ml–1). CFS of Lactobacillus reuteri (2/6) showed the best IE (40.0 %) against F. graminearum CCM 8244 (2/6) at the MIC 1.25 mg.ml–1. However, no inhibitory effect of Bacillus subtilis and Bacillus licheniformis CFS against both strains of F. graminearum were observed, even at the highest tested concentration of 5.0 mg.ml–1.