bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychosocial Care Service in the Mental Health Provision
Authors: Tumanggor Roxsana Devi 
Published: March 2021

The approach of health service can be divided into a medical term and psychosocial term that are applied by the mental health professional. The mental heath services help their clients with mental illness by giving a specific treatments particularly from psychological view. The information in this essay were collected from two databases that are CINAHL and Health Science. It also included the University of Wollongong e-journal database for nursing program. Based on the internet research, it is imperative that the intervention can be delivered in the form of case management. This paper therefore will discuss the psychosocial care for mentally ill clients in terms of concept, components, interventions and benefit in the practical area. The strategies to develop the treatment more effective are also discussed in depth.
Keywords. psychosocial care, medical care, mental health.
Costos ambientales-sociales en el marco de la mercantilización de los recursos naturales. Contextos de vulnerabilidad social-ambiental.
Authors: Doroni Georgina 
Published: March 2021

En el contexto del neo-extractivismo en América Latina (específicamente en Argentina) se pretende abordar los “daños colaterales” que encierran los proyectos de desarrollo y progreso económico sobre las variables socio-ambientales. A través de un análisis de tipo descriptivo y relacional se abordarán los costos ambientales-sociales que dicho accionar genera, acrecentados en sujetos que se encuentran en situaciones de vulnerabilidad -comunidades locales que se ven desplazadas y afectadas por el desarrollo de proyectos económicos-. Esta situación genera una deuda social-ecológica (pasivos ambientales y sociales) que requiere de medidas para la remediación y compensación de dicha deuda y arbitrar mecanismos legales de preservación y prevención de los derechos ambientales.
En función de lo expuesto, el presente trabajo se propone: a) explicitar la relación entre el medio ambiente y los derechos humanos, para luego b) enmarcar la problemática de los costos ambientales-sociales generados por una práctica de mercantilización de los recursos naturales; c) evidenciando la relación entre dichos costos y contextos de vulnerabilidad socio-ambiental; d) abordar medidas de remediación y compensación de la deuda social-ecológica generada y medidas prevención de los derechos ambientales.
Clonal Dissemination of KPC-2, VIM-1, OXA-48-Producing Klebsiella pneumoniae ST147 in Katowice, Poland
Authors: OCHOŃSKA DOROTA , KLAMIŃSKA-CEBULA HANNA , DOBRUT ANNA , BULANDA MAŁGORZATA , BRZYCHCZY-WŁOCH MONIKA 
Published: March 2021

Abstract
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an important bacterium of nosocomial infections. In this study, CRKP strains, which were mainly isolated from fecal samples of 14 patients in three wards of the hospital in the Silesia Voivodship, rapidly increased from February to August 2018. Therefore, we conducted microbiological and molecular studies of the CRKP isolates analyzed. Colonized patients had critical underlying diseases and comorbidities; one developed bloodstream infection, and five died (33.3%). Antibiotic susceptibilities were determined by the E-test method. A disc synergy test confirmed carbapenemase production. CTX-Mplex PCR evaluated the presence of resistance genes bla
CTX-M-type, bla
CTX-M-1, bla
CTX-M-9, and the genes bla
SHV, bla
TEM, bla
KPC-2, bla
NDM-1, bla
OXA-48, bla
IMP, and bla
VIM-1 was detected with the PCR method. Clonality was evaluated by Multi Locus Sequence Typing (MLST) and Pulsed Field Gel Electrophoresis (PFGE). Six (40%) strains were of XDR (Extensively Drug-Resistant) phenotype, and nine (60%) of the isolates exhibited MDR (Multidrug-Resistant) phenotype. The range of carbapenem minimal inhibitory concentrations (MICs, μg/mL) was as follows doripenem (16 to >32), ertapenem (> 32), imipenem (4 to > 32), and meropenem (> 32). PCR and sequencing confirmed the bla
CTX-M-15, bla
KPC-2, bla
OXA-48, and bla
VIM-1 genes in all strains. The isolates formed one large PFGE cluster (clone A). MLST assigned them to the emerging high-risk clone of ST147 (CC147) pandemic lineage harboring the bla
OXA-48 gene. This study showed that the K. pneumoniae isolates detected in the multi-profile medical centre in Katowice represented a single strain of the microorganism spreading in the hospital environment.
O estresse intra-hospitalar e o aumento da pressão arterial entre acompanhantes de pacientes
Authors: Azevedo Arimatéia Portela de , Pereira Majorry de Oliveira , De Abreu Adriana Sales , Dos Santos Daniel Guedes , Silva Michele Nascimento da , Frazão Priscila Damasceno , Moreira Rebeca Castro , Silva Wilzilene Coelho da 
Published: March 2021

Introdução: A internação gera alto grau de estresse e ansiedade na família. O ambiente é percebido por eles como um espaço agressivo e ameaçador, pois evidencia o risco de morte do ente querido. Objetivo: Realizar acompanhamento de valores pressóricos de familiares cuidadores de pacientes internados para averiguar possiveis oscilações relacionadas ao estresse intra-hospitalar. Material e métodos: O presente estudo foi do tipo prospectivo, descritivo com abordagem quantitativa no qual foi realizado o registro pressórico dos acompanhantes de pacientes internados, no período de seis meses e averiguação dos fatores causais de maior estresse entre eles. Resultados: No período foram selecionados, por demanda espontânea, 48 acompanhantes de pacientes internados, dos quais 10,4% já declararam ser hipertensos e dos que declararam não ser hipertensos, 25% tiveram pico hipertensivo no primeiro dia como cuidador e 8,3% no decorrer dos dias, 4,1% teve elevação repentina da pressão arterial tendo que haver intervenção médica urgente. Conclusão: Os fatores estressores relacionados a permanência de um familiar cuidador em um ambiente hospitalar têm grande influência sobre o aumento dos valores pressóricos deles, principalmente ao se tratar de um hospital onde albergam pacientes com doenças infectocontagiosas.
Modelo de assistência ao parto normal: atuação das parteiras no Brasil
Authors: Lima Claudia Moreira de , Pavoski Juliani , Silvestre Grasiela Cristina Silva Botelho , Nascimento Grazielly Nogueira Xavier do , Magalhaes Dayane dos Santos Souza , Ferro Rayanni Bruna Campos 
Published: March 2021

Objetivo: Traçar o perfil bibliométrico da produção científica nacional acerca da assistência ao parto pela obstetrícia informal. Métodos: A metodologia desta revisão foi desenvolvida de acordo com os propósitos da revisão de escopo. Para tanto foram consultadas as bases de dados BDENF, Lilacs, Medline, Pubmed e Scielo com uso dos descritores: assistência ao parto; parto domiciliar e parteira, tendo como auxílio o boleano and e or. Foram selecionados 11 estudos, que foram gerenciados no programa JabRef Reference Manager 2.5, e os dados provenientes foram submetidos a análise estatística no software Prisma. Resultados: Os estudos analisados apontam para uma necessidade de uma fonte de pesquisa dentro desta temática, que, apesar de importante e constante, ainda é escassa. Conclusão: Foi evidenciado a necessidade de desenvolverem pesquisas considerando todos os aspectos relacionados a atuação de parteiras antigamente e atualmente, bem como a utilização desta metodologia, viabilizando possíveis reflexões de pesquisadores, meio acadêmico e sociedade como um todo.
Educação em saúde para mães com recém nascidos hospitalizados: relato de experiência
Authors: Campos Marcos Pires , Rodrigues Jessiane de Paulo , Sampaio João Victor Ferreira , Vasconcelos Layse Fernandes Queiroz , Tomaz Letícia de Souza , Cavalcante Francisco Marcelo Leandro , Sousa Francisco Willian Melo de , Dias Francisca Isaelly dos Santos , Silva Maria Adelane Monteiro da , Freitas Cibelly Aliny Siqueira Lima 
Published: March 2021

O estudo objetiva descrever as ações educativas realizadas com mães de crianças prematuras hospitalizadas. Trata-se de um relato de experiência, com abordagem qualitativa, desenvolvido por estudantes de Enfermagem, a partir de oficinas realizadas numa casa de apoio denominada Casa da Mamãe, vinculada a um hospital escola da região norte do Ceará. Os encontros foram realizados no período de maio a julho de 2019 e ocorriam semanalmente. Para coleta das informações utilizou-se o diário de campo, e posteriormente, fez-se análise dos registros junto à literatura. Realizou-se nove encontros com as puérperas, e nestes trabalhou-se, por meio de oficinas educativas e metodologias ativas as seguintes temáticas: cuidando do cuidador, cuidados com o recém-nascido, promovendo e compartilhando sentimentos, entre outras ações feitas por meio de dinâmicas, massagens, pinturas e arteterapia. As atividades realizadas com o grupo de puérperas proporcionaram momentos de aprendizagem a todos os envolvidos, reafirmando a ideia de que as ações de promoção à saúde devem ser eminentemente participativas e transformadoras. A equipe de acadêmicos de enfermagem auxiliou no favorecimento do vínculo, por meio das atividades de educação em saúde, momentos de relaxamento e de autoconhecimento, além de fortalecer a relação de apoio mútuo entre as mães.
Perancangan Sistem Microgrid Untuk Mempercepat Akses Terhadap Energi Listrik (Energy Access) Pada Kawasan Wisata Setu Rawalumbu Kota Bekasi
Authors: Marpaung Charles O.P. , Siahaan Uras , Sudarwani Margareta M. 
Published: March 2021

Setu Rawalumbu, Kecamatan Rawalumbu, Kota Bekasi, Propinsi Jawa Barat, Indonesia adalah satu dari ribuan setu yang ada di Indonesia, yang masih belum dimanfaatkan secara optimal, Permen PUPR No. 9 Tahun 2015 Tentang Penggunaan Sumber Daya Air pada pasal 43 ayat (2), dan Permen PUPR No. 28 Tahun 2015 Tentang Garis Sempadan Sungai dan Garis Sempadan Danau pada pasal 23. Ini bisa dilihat dari munculnya banyak perumahan di daerah tersebut termasuk fasilitas umum dan fasilitas sosial, dan menjadi tempat pembuangan sampah yang berasal dari daerah sekitar. Setu ini juga dicanangkan sebagai Daerah Kawasan Wisata yang fokusnya pada eko-wisata (eco-tourism), yang akan memberikan manfaat ekonomi kepada masyarakat setempat dan mendukung upaya pelestarian lingkungan alam dan budaya. Sebagai Daerah Kawasan Wisata, energi listrik yang berkelanjutan di Setu ini perlu dioptimalkan sesuai dengan kriteria goal ke 7 dari Sustainable Development Goals (SDGs), dengan membangun microgrid energi terbarukan dengan back-up generator diesel dan memanfaatkan potensi sumberdaya matahari. Energi listrik yang dibangkit dari sinar matahari melalui solar PV adalah energi yang bersih atau hijau (clean energy atau green energy). Sistem ini lebih andal, murah dan berdampak lingkungan rendah. Dengan cara ini, Daerah Kawasan Wisata Setu Rawalumbu dapat menjadi daerah eko-wisata (eco-tourism).

Kata Kunci: Setu; Rawalumbu; Energi
PELATIHAN PENGGUNAAN METODE MENGAJAR REMAJA DI MASA PANDEMI COVID-19 DI HKBP RESORT JATISAMPURNA BEKASI
Authors: Sianipar Desi , Rambitan Stanley , Sairwona Wellem , Zega Yunardi Kristian 
Published: March 2021

Metode mengajar merupakan cara atau alat yang digunakan oleh para pendidik untuk mengimplementasikan rencana yang sudah disusun dalam kegiatan pembelajaran, agar tujuan yang telah disusun tercapai secara optimal. Dengan demikian, gereja perlu menyediakan para pendidik, khususnya pendidik remaja yang berkualitas, salah satu kualitas yang harus dimiliki oleh para pendidik remaja adalah mampu menggunakan metode mengajar yang sesuai dengan kebutuhan remaja, khususnya di masa pandemi covid-19 sekarang ini. Oleh karena itu, kegiatan ini dirancang untuk membantu para pembina remaja dalam penggunaan metode mengajar yang sesuai dengan kebutuhan remaja dan untuk meningkatkan keterampilan bagi para pendidik dalam mengajar remaja di masa pandemi Covid-19. Hasil yang diperoleh dari kegiatan ini adalah menghasilkan para pembina remaja yang dapat memahami metode mengajar khususnya dalam Alkitab, metode mengajar secara luring, prinsip-prinsip dalam pemilihan metode mengajar dan cara mengajar remaja yang kreatif di masa pandemi Covid-19 dengan penggunaan metode pembelajaran daring.

Kata kunci: Pelatihan, Metode Mengajar, Pandemi Covid-19, dan Remaja.
Dysbiosis and Implication of the Gut Microbiota in Diabetic Retinopathy
Authors: Huang Yinhua , Wang Zhijie , Ma Hongjie , Ji Shangli , Chen Zhongping , Cui Zekai , Chen Jiansu , Tang Shibo 
Published: March 2021

The pathogenesis of type 2 diabetes mellitus (T2DM) is commonly associated with altered gut bacteria. However, whether the microbial dysbiosis that exists in human diabetic patients with or without retinopathy is different remains largely unknown. Here, we collected clinical information and fecal samples from 75 participants, including 25 diabetic patients without retinopathy (DM), 25 diabetic patients with retinopathy (DR), and 25 healthy controls (HC). The gut microbial composition in the three groups was analyzed using 16S ribosomal RNA (rRNA) gene sequencing. Microbial structure and composition differed in the three groups. The α and β diversities in both the DM and DR groups were reduced compared with those in the HC group. Blautia was the most abundant genus, especially in the DM group. In addition, increased levels of Bifidobacterium and Lactobacillus and decreased levels of Escherichia-Shigella, Faecalibacterium, Eubacterium_hallii_group and Clostridium genera were observed in the DM and DR groups compared with the HC group. Furthermore, a biomarker set of 25 bacterial families, which could distinguish patients in the DR group from those in the DM and HC groups was identified, with the area under the curve values ranging from 0.69 to 0.85. Of note, Pasteurellaceae, which was increased in DM and decreased in DR compared with HC, generated a high AUC (0.74) as an individual predictive biomarker. Moreover, 14 family biomarkers were associated with fasting blood glucose levels or diabetes, with most of them being negatively correlated. In summary, our study establishes compositional alterations of gut microbiota in DM and DR, suggesting the potential use of gut microbiota as a non-invasive biomarker for clinical and differential diagnosis, as well as identifying potential therapeutic targets of diabetic retinopathy.
Gut Microbiota of Chinese Obese Children and Adolescents With and Without Insulin Resistance
Authors: Yuan Xin , Chen Ruimin , Zhang Ying , Lin Xiangquan , Yang Xiaohong , McCormick Kenneth L. 
Published: March 2021

ObjectiveThe intestinal flora of gut microbiota in obese Chinese children and adolescents with and without insulin resistance (IR) was analyzed, as well as associations between the gut microbiota and two serum cytokines related to glucose metabolism, adropin and angiopoietin-like 4 (ANGPTL4).MethodsClinical data, fecal bacterial composition, glucose-related hormones, and serum adipokines (adropin and ANGPTL4) were analyzed in 65 Chinese children with exogenous obesity. The composition of the gut microbiota was determined by 16S rRNA-based metagenomics and IR was calculated using the homeostasis model assessment (HOMA).ResultsThe 65 obese subjects were divided into two groups: insulin sensitive (IS) (n=40, 57.5% males) or IR (n=25, 60% males). Principal coordinates analysis revealed that the gut microbiota samples from the IS group clustered together and separated partly from the IR group (p=0.008). By Mann-Whitney U-test, at a phylum level, a reduction of Firmicutes and an increase of Bacteroidetes in the IR subjects was observed. LEfSe analysis revealed that IS subject, when compared to their IR counterparts, harbored members of the order Coriobacteriales, Turicibacterales, Pasteurellales and family Turicibacteraceae, that were significantly more abundant. In contrast, the IR subjects had members of family Peptococcaceae that were significantly more prevalent than the IS subjects (all p&lt;0.05). Spearman’s correlation analysis revealed that serum ANGPTL4 was positively associated with genus Bacteroides, Butyricimonas, and Alistipes, and adropin was positively associated with genus Anaerostipes and Alistipes, and negatively associated with genus Blautia (all p&lt;0.05).ConclusionIn obese children, the gut microbiome in IR subjects was significantly discordant from the IS subjects, and the abundance of some metabolism-related bacteria correlated with the serum concentrations of adropin and ANGPTL4. These observations infer that the gut microbiota may be involved in the regulation of glucose metabolism in obesity.
Dry and Wet Events in Andean Populations of Northern Peru: A Case Study of Chachapoyas, Peru
Authors: Rascón Jesús , Gosgot Angeles Wildor , Quiñones Huatangari Lenin , Oliva Manuel , Barrena Gurbillón Miguel Ángel 
Published: March 2021

Climate change and population growth have heavily impacted the ecosystem’s water resources, essential for anthropogenic activities. These also apply to the Andean city of Chachapoyas, located in the north of Peru, which has gone through a substantial population increase in recent years, therefore increasing its water demand. This research aimed to assess dry and wet events from 1981 to 2019 that have taken place in Chachapoyas, by applying the Standardized Precipitation Index (SPI), and the Standardized Precipitation Evapotranspiration Index (SPEI). These events were periodically characterized, and the index relationship was determined at different timescales. The SPI and SPEI indices were calculated at the city’s only weather station for timescales of 3, 6, 12, and 24 months using climatic data. The indices showed a remarkably consistent behavior for timescales of 12 and 24 months detecting an extreme drought event in 1993, while for timescales of 3 and 6 months a severe drought event was detected in the same year. Contrastingly, there has been an increase in extreme wet events in the last decade, hence Chachapoyas is categorized between "moderate drought" and “moderate wet”. It should be noted that the indices have a high correlation between them when calculated for the same timescale. The results were statistically significant (p &lt; 0.05). Considering the results obtained related to dry and wet events and their relation with economic activities such as environmental management, we can conclude that the SPI and SPEI indices are useful and valuable tools for local and regional governments.
Trimethylamine-N-Oxide Levels Are Similar in Asymptomatic vs. Symptomatic Cerebrovascular Atherosclerosis
Authors: Heyse Miriam , Schneider Christine , Monostori Peter , Schwarz Kathrin V. , Hauke Jana , Drüschler Katharina , Berberich Anne , Zorn Markus , Ringleb Peter A. , Okun Jürgen G. , Mundiyanapurath Sibu 
Published: March 2021

Introduction: Trimethylamine-N-oxide (TMAO) is correlated with atherosclerosis and vascular diseases such as coronary heart disease and ischemic stroke. The aim of the study was to investigate whether TMAO levels are different in symptomatic vs. asymptomatic cerebrovascular atherosclerosis.Methods: This was a prospective, case–control study, conducted at a tertiary care university hospital. Patients were included if they had large-artery atherosclerosis (TOAST criteria). Symptomatic patients with ischemic stroke were compared with asymptomatic patients. As primary endpoint, TMAO levels on admission were compared between symptomatic and asymptomatic patients. Univariable analysis was performed using Mann–Whitney U test and multivariable analysis using binary logistic regression. TMAO values were adjusted for glomerular filtration rate (GFR), age, and smoking.Results: Between 2018 and 2020, 82 symptomatic and asymptomatic patients were recruited. Median age was 70 years; 65% were male. Comparing symptomatic (n = 42) and asymptomatic (n = 40) patients, no significant differences were found in univariable analysis in TMAO [3.96 (IQR 2.30–6.73) vs. 5.36 (3.59–8.68) μmol/L; p = 0.055], GFR [87 (72–97) vs. 82 (71–90) ml/min*1.73 m2; p = 0.189] and age [71 (60–79) vs. 69 (67–75) years; p = 0.756]. In multivariable analysis, TMAO was not a predictor of symptomatic cerebrovascular disease after adjusting for age and GFR [OR 1.003 (95% CI: 0.941–1.070); p = 0.920]. In a sensitivity analysis, we only analyzed patients with symptomatic stenosis and excluded patients with occlusion of brain-supplying arteries. Again, TMAO was not a significant predictor of symptomatic stenosis [OR 1.039 (0.965–1.120), p = 0.311].Conclusion: TMAO levels could not be used to differentiate between symptomatic and asymptomatic cerebrovascular disease in our study.
RETRACTED: Overexpressed Tumor Suppressor Exosomal miR-15a-5p in Cancer Cells Inhibits PD1 Expression in CD8+T Cells and Suppresses the Hepatocellular Carcinoma Progression
Authors: Zhang Hong-Yu , Liang Hong-Xia , Wu Shu-Huan , Jiang He-Qing , Wang Qin , Yu Zu-Jiang 
Published: March 2021

BackgroundHepatocellular carcinoma (HCC) is the most common primary liver tumor, and the main reason is the unclear pathogenesis of HCC, which leads to a high fatality rate of HCC. Therefore, it is of great clinical significance to explore the molecular mechanism of HCC and find a targeted therapeutic approach from the molecular level.Materials and MethodsMicroRNA-15a-5p (miR-15a-5p) expression level was measured by bioinformatics and qRT-PCR. Luciferase assay and RIP assays were used to verify the relationship between programmed cell death protein 1 (PD1) PD 1 with miR-15a-5p. Exosomes were identified using TEM, Zetasizer Nano ZS, and western blot. Edu, Transwell, and scratch assay were performed to explore the role of miR-15a-5p or exo-miR-15a-5p on HepG2 cells progression.ResultsMicroRNA-15a-5p (miR-15a-5p) was decreased in HCC tissues and cell lines, which indicated a poor prognosis. Overexpression of miR-15a-5p inhibited viability, proliferation, migration and invasion of HepG2 cells. Then, we isolated exosomes from cancer cells, and found that miR-15a-5p was packaged into exosomes from cancer cells. Furthermore, exo-miR-15a-5p was secreted into CD8+ T cells, then directly inhibited PD1 expression via targeted binding. Then, we co-cultured CD8+ T cells transfected with PD1 with HepG2 transfected with miR-15a-5p, PD1 remitted the inhibitory role of miR-15a-5p on HCC progression.ConclusionTogether, present study revealed exo-miR-15a-5p from cancer cells inhibited PD1 expression in CD8+ T cells, which suppressed the development of HCC.