bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multilevel percutaneous vertebroplasty: safety, efficacy and long-term outcomes
Authors: Dalai Sibasankar , Datla Aravind V. 
Published: December 2021

<p><strong>Background:</strong> The pain in vertebral compression fractures is severe, leading to reduced mobility and quality of life. Percutaneous vertebroplasty is a minimally invasive procedure for treating various spinal pathologies. This study evaluated the usefulness and safety of multilevel PVP (two to three vertebrae) in managing VCF.</p><p><strong>Methods:</strong> This retrospective study evaluated 59 vertebral levels in 28 patients with VCF who had been operated on for multilevel PVP (two to three levels). There were 22 females and six males, and their ages ranged from 36 to 79 years, with a mean age of 68.95 years. We had injected two levels in 25 patients and three levels in 3 patients. The visual analogue scale was used for pain intensity measurement, and plain X-ray films, computed tomography scan and magnetic resonance imaging was used for radiological assessment. The mean follow-up period was 13.8 months (range, 11-19).</p><p><strong>Results:</strong> Significant pain improvement was recorded in 26 patients (92.85%). More remarkable improvement in pain was noticed in the immediate postoperative period than in the subsequent follow-ups. Asymptomatic bone cement leakage anteriorly and into the disk spaces in two patients. Isolated anterior leakage has occurred in one patient. There was no encounter of pulmonary embolism.</p><p><strong>Conclusions:</strong> Multilevel PVP for the treatment of VCF is a safe and effective procedure that can significantly reduce pain and improve patient condition without any significant morbidity. It is considered a cost-effective procedure allowing a rapid restoration of patient mobility.</p><p> </p>
Single center, observational study to analyze correlation between vitamin D-3 deficiency and age in patients with orthopedic disorders
Authors: Rathod Girish , Raut Nitin , Borole Pushkar , Shetty Chandan , Gawali Vijaykumar 
Published: December 2021

<p><strong>Background:</strong> Vitamin D deficiency has been strongly associated with various health outcomes, including all-cause mortality. Chronic vitamin D deficiency in adults and in old age results in osteomalacia, osteoporosis, muscle weakness, and increased risk of fall and long bone fractures. <strong></strong></p><p><strong>Methods:</strong> We examined records of 1029 such patients and to analyze association of vitamin d-3 levels and categories of age groups (1-20, 21-30, 31-40, 41-50, 51-60, 61-70, 71-80, 81-90 years). We categorized mild, moderate and severe cases age wise.</p><p><strong>Results: </strong>During the study period records for 1029 patients were evaluated, of which 347 (33.72%) male and 682 (66.27) were female the mean age with standard deviation for male was 38.25±15.64 years and for female was 41.43±15.23 years. Vitamin D deficiency (&lt;20 ng/ml) was present in 623 patients (61%), 189 patients (18%) had vitamin D level 20-30 ng/ml and 217 patients (21%) had sufficient levels of vitamin D.</p><p><strong>Conclusions:</strong> Our study concludes that although there is high prevalence of vitamin D-3 deficiency across all age groups among orthopedic patients, age group 31-40 years, was found to be more affected.</p><p><strong> </strong></p>
Surgical management of giant cell tumor in adolescent by excision or curettage followed by fibular strut graft
Authors: Bhaskar Reddy K. Vijaya , Chary N. Brahma , Mogili Chenna K. 
Published: December 2021

<p class="abstract">Giant cell tumour (GCT) in adolescent is a rare tumour. It commonly occurs in skeletally mature patients aged between 20-40 years. In adults it is seen in epiphyseal region. In patients with intact physis, it arises from the metaphysis. Giant cells are more common in females. It is more common in the ends of long bones of distal end of femur, proximal tibia, and distal radius. 14 cases of surgical management of GCT by excision or curettage in adolescent followed by fibular strut graft. 1 year follow up of all cases of GCT in adolescent treated with excision or curettage followed by fibular strut graft was done. Out of 14 patients, 12 patients did not develop any recurrence of GCT. 2 patient developed recurrence after 6 months. All the patients were able to attain good range of movements 2 months after surgery. GCT in adolescent surgically treated with excision or curettage followed by fibular graft had excellent results in terms of recovery of daily activities, wound healing. Chances of recurrence more in patients treated with curettage and bone grafting.</p><p class="abstract"> </p>
Assessment of Distortion Product Otoacoustic Emissions Input-Output Function in Individuals with and without Musical Abilities
Authors: Sannamani Kavitha Gurunathgowda , Chakraborty Madhumanti , Devi Neelamegarajan , Prabhu Prashanth 
Published: December 2021

Background and Aim: Musical training has shown to bring about superior performance in several auditory and non-auditory tasks compared to those without musical exposure. Distortion product otoacoustic emissions (DPOAE) input-output function can be an indicator of the non-linear functioning of the cochlea. The objective of this study was to evaluate and compare the differences in the slope of DPOAE input-output function in individuals with and without musical abilities.
Methods: Twenty normal-hearing individuals were considered in the age range of 18–25 years. They were divided based on the scores obtained on the questionnaire of musical abilities, as individuals with and without musical abilities. DPOAE input-output function was done for each of the two groups. The slope of the DPOAE input-output function was compared at different frequencies between the groups.
Results: The results of the Mann Whitney test revealed that the slope was significantly steeper at 2000, 3000, 4000 and 6000 Hz in individuals with musical abilities. There was no significant difference in slope at 1000 and 1500 Hz.
Conclusion: The increased steepness of the slope indicates a relatively better functioning of the cochlea in individuals with musical abilities. The enhanced perception of music may induce changes in the cochlea resulting in a better appreciation of music.
Effects of Chlorogenic Acid on Epileptic Behavior and mRNA Expressions of Brain Derived Neurotrophic Factor in the Brain of Aged Rats
Authors: Soleimani Hossain , Rezvani Mohammad Ebrahim , Hafizi-Barjin Zainab , Esmaeilidehaj Mansour , Zaremehrjerdi Fatemeh 
Published: December 2021

Introduction: The present study was conducted to evaluate the effect of chlorogenic acid (CA) and Diazepam (DZP) on epileptic complication that induced by repetitive intra-peritoneal injections of pentylenetetrazle (PTZ) in aged rats.
Methods: Twenty-four month-old male Wistar rats (age > 12 months, 300-350 g) were divided in 4 experimental groups. Animal in control group (PTZ + Vehicle) received only PTZ. Animal in treated groups (PTZ + DZP, PTZ + CA10 and PTZ + 25) received diazepam 2 mg/kg, CA 10 mg/kg, or CA 25 mg/kg. All drugs injection were performed 30 min prior to each PTZ injection. Epilepsy was induced by injection of subconvulsive dose of PTZ every other day until the rats were completely kindled or epileptic. After each PTZ injection, animal was monitored for 40 min and epileptic behaviors were scored. At the end of the study, rats were sacrificed and the brains removed for evaluation of histological changes and Brain Derived Neurothrophic Factor (BDNF) gene expression.
Results: CA at dose of 25 mg/kg reduced percent of generalized tonic-clonic seizure (GTCS) in aged rats (24%) in compared to control group (50%) (p < 0.05). The latencies to the start of GTCS were decreased in both dose of CA (p < 0.05). Also, the percent of survived neurons in rats treated with CA (154%) were significantly higher relative to that of control animals (100%) (p < 0.05). The mRNA levels of BDNF significantly increased in CA treated rats (p < 0.05).
Conclusion: Hence, these findings revealed that CA have antiepileptic, neuroprotective and trophic effects in aged rats. CA can protect aged brain from deteriorative processes and save neurons during epilepsy in rats.
Clinical consequences of Hypotension in patient with organophosphate poisoning
Authors: Kumar Thakur Dr. Digbijay , Datri Jha Dr. Sidhi , Mahaseth Dr. Rameshwar , Pande Dr. Manish 
Published: December 2021

Objective: Aim of study is to describe the clinical consequences of hypotension in patient with organophosphate poisoning.
Method: In the retrospective cohort study, we analyzed data of 66 patients with organophosphate poisoning who were treated at Bir Hospital, Nams Kathmandu. Data from those with hypotension and normal blood pressure were compared to identify significant clinical consequences.
Results: All together 66 patients were enrolled in this study out of which 44(66.7%) were female and 22(33.3%) were male. After analyzing data, we found 18.2% of case with severe poisoning (ACHE < 700 U/L). Among all, 41(62%) were found to have normal blood pressure and 25(37.9%) were found to have low blood pressure. Among those with hypotension, around 56% were found to have prolonged QTc interval, p < 0.003 and there was statistically significant association between QTc prolongation and vasopressor requirement, X2(1) = 22.98, P < 0.001. Patients requiring higher dose to reach atropinization had statistically significant hypotension, P < 0.001. Those with low blood pressure were found to require more days of hospital admission, P < 0.001. Patients with hypotension were found to have severe poisoning both on the basis of POP Score severity grading, 16(64%) P <0.002 and ACHE Severity scale, 7(28%) P < 0.05. In comparison with normal blood pressure group, low blood pressure group had significantly more chance of developing complications like septic shock (2), aspiration pneumonia (5), ARDS (1) and bed sore, P = 0.002. Vasopressor requirement was significantly more among those with low blood pressure, P < 0.001. Most of hypotensive patients were needing ICU care, found to have higher WBC count P = 0.002 and lower GCS Score at admission P < 0.001. There was positive correlation between hypotension and POP Score at admission P < 0.001.
Conclusion: Hypotension is a common complication in patient with organophosphate poisoning and is associated with higher POP Score, lower ACHE level, lower GCS Score, increased vasopressor requirement, more hospital stays, increasing ICU admission, more chance of developing septic shock and aspiration pneumonia.
“Pleurotomy during CABG on the Clinical Outcome Following Left Internal Mammary Artery (LIMA) Harvesting”
Authors: Rahman Md. Magfur 
Published: December 2021

Background: The internal mammary artery (IMA) is the graft of choice for coronary artery bypass grafting (CABG) due to superior patency and enhanced patient survival. Pleurotomy during coronary artery bypass grafting (CABG) may cause post-operative events, mostly pulmonary complications.
Objective: To assess the impact of intact pleura during left internal mammary artery harvesting on clinical outcome.
Materials and Methods: This Cross sectional observational study was carried out in the Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from January 2019 to December 2019.101 patients who underwent Department of Cardiac Surgery, BSMMU were enrolled in this study and divided into two groups: group A (n = 48, 36 male and 12 female patients at a mean age of 56.5 ± 11.2 years) underwent routine CABG and pleurotomy and group B (n = 53, 45 male and 8 female patients at a mean age of 55.4 ± 10.3 years) had CABG with intact pleura. The patients were compared regarding their demographic data, surgical data, and postoperative events.
Results: The Incidence Of Postoperative Pericardial Effusion Was Similar Between The Groups, But The Incidence Of Postoperative Pulmonary Complications Such As Pleural Effusion (Except For Mild Pleural Effusion) On The Second (No: 10.4%, mild: 41.7%, moderate: 45.8% and severe: 2.1% in group A versus no: 42.6%, mild: 44.4%, moderate: 13%, and severe: 0 in group B) and fifth postoperative days (no: 27.1%, mild: 33.3%, moderate: 35.4%, and severe: 4.2% in group A versus no: 42.6%, mild: 44.4%, moderate: 13%, and severe: 0 in group B) was significantly lower in group B (p value < 0.001 and p value = 0.007, respectively). Also, the incidence of atelectasis (except for mild atelectasis) on the second (no: 2.1%, mild: 22.9%, moderate: 72.9%, and severe: 2.1% in group A versus no: 9.2%, mild: 59.3%, moderate: 31.5%, and severe: 0 in group B) and fifth postoperative days (no: 22.9%, mild: 39.6%, moderate: 35.4%, and severe: 2.1% in group A versus no: 39.6%, mild: 49.1%, moderate: 11.3%, and severe: 0 in group B) was significantly higher in group A (p value < 0.001 and p value = 0.004, respectively). Postoperative partial oxygen pressure and O2 saturation were similar between the groups, but partial carbon dioxide pressure was significantly lower in group A (p value = 0.017). Amount of bleeding (p value = 0.008) and duration of hospitalization (p value = 0.002) were significantly higher in group A than those in group B.
Conclusion: Our results indicate that keeping the pleura intact has beneficial effects on the respiratory function, without increasing the incidence of postoperative pericardial effusion.
Performance of Pigeon Pea (Cajanus cajan) Varieties under Different Soil Amendments in Ndokwa, Delta State, Nigeria
Authors: Ossai C.O. , Ojobor S.A. , Akpeji S.C. , Emuh F.N. 
Published: December 2021

Background: Pigeon pea is an important legume worldwide that is not cultivated by the farmers in Ndokwa, Delta State. Hence, the study looked at the possibility of evaluating the potential of pigeon pea in Ogume, a community in Ndokwa. Methods: Top soils were collected from a fallowed land mixed thoroughly and filled into 4 kg bags and were divided into 3. The 1st was amended with poultry manure, 2nd was NPK 15:15:15 amended and 3rd was without amendment, tested with two varieties of Cajanus cajan. The experiment was a 2 by 3 factorial, in a completely randomized design with 3 replicates. Residual effects of the amendments were evaluated in 2020. Soil samples were taken to establish the fertility status before amendment and at harvest. Data were taken on the agronomic and yield parameters and were analyzed using ANOVA while means were separated using LSD at P≤0.05. Result: Result obtained showed that the tallest plants (9.83±0.51) were observed in the poultry manure in 2019 while the fallowed plots had the tallest plants (11.17±0.49) in 2020, while in both years, the number of pods and dry pod weight was insignificant among the treatments and varieties. This shows that farmers do not need to spend much finance in amending the soil for pigeon pea cultivation in Ndokwa community, Delta State.
Factors Affecting the Salinity Intrusion at the Paddy Field in Thua Thien Hue Province, Vietnam
Authors: Khoa Nguyen Phuc , Dien Nguyen Thanh , Ngu Nguyen Huu , Trung Hoang Dinh 
Published: December 2021

Background: Several coastal regions in Vietnam have been suffered from salinity intrusion as a consequence of global climate change. However, there are limited studies on saline intrusion in Vietnam. This paper aimed to investigate the salinity intrusion of water and soil samples in paddy fields along Tam Giang lagoon, Thua Thien Hue province and clarify the factors affecting the salinity level. Methods: We measured the salinity concentrations (EC, Electrical conductivity) of water and soil samples in paddy fields at different distances (400, 600, 800, 1000 and 1200 m) from Tam Giang lagoon. The multiple regression analysis was performed to figure out the factors affecting the salinity concentrations. Result: The salinity concentrations of water were assessed as 48% high saline (10-25 dS m-1), 34% moderately saline (2-10 dS m-1), 2% slightly saline (0.7-2 dS m-1) and 15% non-saline ( less than 0.7 dS m-1). As for surface soil in paddy field, 14.3% moderately saline (4-8 dS m-1), 35.4% slightly saline (2-4 dS m-1) and 50.3% non-saline (0-2 dS m-1) were measured. A significantly positive correlation was found between salinity concentrations of water and soil (n = 175, r = 0.886, p less than 0.01). The distances from salinity sources, Tam Giang lagoon and shrimp pond, were major factors affecting the salinity concentrations. The paddy fields near Tam Giang lagoon and shrimp pond have higher salinity concentrations compared to those areas close to the residential area. The surface water in the paddy field within 1000 m from the salinity source was assessed as saline that might harm the paddy soil and rice production. The results of this study provide highly useful information for local policymakers and farmers about the status of salinity intrusion in paddy land.
Fruit Morphology of Durio zibethinus L. in Jelebu, Negeri Sembilan, Malaysia
Authors: Shamin-Shazwan K. , Razali Nurul Irfan Anis , Rozilawati S. , Amri C.N.A.C. , Rusea G. 
Published: December 2021

Background: Jelebu is one of Negeri Sembilan districts of Malaysia, famous for its wide variety of D. zibethinus. It is also recognized as the top hotspot area for consumers looking for genuine Durian Kampung. This study aimed at discovering and recording significant morphological data in identification and classification of D. zibethinus fruit in Jelebu. Methods: Fifty-three accessions of durian were observed from January 2020 to September 2020 in accordance with Malaysia’s Department of Agriculture guidelines. Result: Forty-one parameters were compiled and divided into two primary morphological data sets: external and internal structures. Size, shape, color and aril characteristics of fruits were several engrossing parameters for identifying and classifying D. zibethinus varieties. Fruit weight varies between 665 g and 2.7 kg, depending on size. The results also revealed six different variants in the fruit shape and color. Aril characteristics included a variety of aril color and thickness ranging from 0.23 cm to 1.17 cm. Therefore, this research revealed that external and internal morphological data from durian fruits were valuable for recognizing and categorizing D. zibethinus Jelebu variants.
Pelatihan Pembuatan Media Articulate Storyline di Lingkungan Lahan Basah Bagi Guru MGMP IPA Kabupaten Barito Kuala
Authors: Zainuddin Zainuddin , Mastuang Mastuang , Misbah Misbah , Dari Sulastri Wulan , Agustina Aulia , Mudha Amirul Azis Anshari , Lazuardi Nana Sophia , Andiantosa Syahwarunna Dwipa 
Published: December 2021

Kegiatan pengabdian ini bertujuan untuk meningkatkan kompetensi pedagogik guru MGMP IPA Kabupaten Batola dalam hal pembuatan media pembelajaran melalui Articulate Storyline di lingkungan lahan basah. Pelatihan dilaksanakan secara daring yang diikuti 24 orang peserta, yakni guru-guru anggota MGMP IPA Kabupaten Batola. Metode kegiatan pengabdian ini meliputi: perencanaan, tindakan, observasi, evaluasi, dan refleksi. Pelaksanaan pelatihan secara luring dilaksanakan sebanyak dua pertemuan, yang terdiri dari konseptual dan praktik pembuatan media menggunakan Articulate Storyline. Angket digunakan untuk mengukur respon peserta terhadap pelaksanaan kegiatan. Adapun hasil kegiatan pengabdian ini adalah: 1) dihasilkannya media pembelajaran melalui Articulate Storyline di lingkungan lahan basah, dan 2) kegiatan ini mendapatkan respon yang sangat baik pada bagian keahlian dan kesiapan 94,00%, pada kegunaan materi yang disampaikan mendapatkan respon sangat baik 91,33%, dan kesesuaian pelaksanaan pelatihan mendapatkan respon baik 89,50%,materi yang disampaikan 90,00%, dan fasilitas yang diberikan 92,00%mendapatkan respon yang sangat baik.This service activity aims to improve the pedagogic competence of the IPA MGMP teachers in Batola Regency to make learning media through Articulate Storyline in a wetland environment. The training was conducted online by 24 participants, namely teachers from the IPA MGMP in Batola Regency. The method of this service activity includes planning, action, observation, evaluation, and reflection. The offline training was carried out in two meetings, consisting of conceptual and practical media creation using Articulate Storyline. Questionnaires are used to measure participants' responses to the implementation of activities.The results of this service activity are: 1) the production of learning media through Articulate Storyline in a wetland environment, and 2) this activity gets a very good response in the expertise and readiness section of 94.00%, on the usefulness of the material presented gets a very good response 91 .33%, and the suitability of the training implementation got a good response 89.50%, the material delivered 90.00%, and the facilities provided 92.00% got a very good response.
Pattern of Antibiotics Use in Adult Patients with Urinary Tract Infection (UTI)
Authors: Kurniawati Hidayatul , Auliyanah Anisa 
Published: December 2021

Abstract: Introduction: Urinary tract infection (UTI) is an infectious disease caused by the growth and proliferation of bacteria in the urinary tract, including infections in the bladder to the renal parenchyma with a certain number of bacteria in the urine. The use of antibiotics is therapy that commonly used to treat infectious diseases caused by bacteria. Irrational use of antibiotics can lead to bacterial resistance and toxicity. Objective: To determine the rationality of using antibiotics in adult patients with a urinary tract infection (UTI) in the X Hospital Yogyakarta from January-December 2017.Methods: This study is a non-experimental study with a descriptive observational study design and retrospective data collection. The sample of this study was inpatients with a diagnosis of urinary tract infection (UTI) and was recorded in the Medical Record X Hospital Yogyakarta for the period January-December 2017 which was included in the inclusion criteria. Results: Medical records that were included in the inclusion criteria were 61. The single most widely used antibiotic was ceftriaxone in 25 cases (44.64%) and the most widely used combination antibiotic was ceftazidime + levofloxacin in 2 cases (40%). The use of antibiotics with the right indication was 61 patients (100%), the right type was 61 patients (100%), the correct duration was 54 patients (88.52%), the right dose was 61 patients (100%), the right interval was 60 patients (98.36%) and the right route of administration was 61 patients (100%). Keywords: Urinary tract infection, antibiotic, rational
Survival Rate Analysis of Early Stage Cervical Cancer Patients after Radical Hysterectomy in Ulin Banjarmasin General Hospital, Indonesia
Authors: Teguh Setyo , Hariadi Hariadi , Armanza Ferry , Sabaruddin Hermin 
Published: December 2021

Abstract: Cervical cancer is a gynecologic disease that has a high level of malignancy and is a major cause of death from cancer in women. To be used as educational material for patients with cervical carcinoma when if there is known outcome of radical hysterectomy in patients with IB-IIA cervical carcinoma, it can be used as a basic data to know the success rate of radical hysterectomy.The sample was collected by consecutive sampling and we found a total of 55 IB-IIA cervical carcinoma patients who underwent a radical hysterectomy. The samples that met the inclusion criteria are 30 people. Data analysis using Chi-square/Fisher method (significant p-value <0.05).In this study, 16.7% of patients with cervical carcinoma from IB to IIA died in 3 years after radical hysterectomy was performed. The average age of patients with stage IB to IIA cervical carcinoma was 48.03 ± 12.21 years with ages ranging from 23 to 78 years. Stage IIA is 16 times more significantly at risk for mortality in cervical carcinoma patients than stage IB. The 3-year survival rate for patients with stage IB to IIA cervical carcinoma after radical hysterectomy was 83.3% with an average life span of 32.8 months. Patients with stage IB to IIA cervical carcinoma after radical hysterectomy have an average disease-free interval (DFI) of 33.0 ± 5.74 months. Keywords: Cervical Cancer, Radical Hysterectomy, Survival Rate