bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adherence to Anti-coagulant therapy in elderly patients with Atrial fibrillation in the Kyrgyzstan
Authors: Bazira Kanat kyzy , Kinderbaeva Nazgul , Karataeva Gulnora , Mamatova Sabira , Kundashev Ulan , Mamatov Sagynali 
Published: October 2021

Introduction: Anticoagulant therapy can prevent adverse outcomes of Atrial fibrillation (AF), reducing the risk of stroke by 64% and death by 25%. The present study aimed to assess treatment adherence in elderly patients with non-valvular atrial fibrillation (NVAF) who were prescribed the vitamin K antagonist warfarin.

Materials and methods: In the present retrospective study, we analyzed the medical records of 202 elderly outpatients with NVAF aged between 65 and 74 years (mean ± SD: 68.7 ± 10.2 years).

Results: Problems associated with warfarin arose throughout the follow-up period. After 1 month of treatment, the number of patients taking warfarin had decreased to 71.3% of all patients; less than half of the patients (46%) were still taking the drug. In subsequent periods, the number continued to decrease; of all patients who had been prescribed warfarin with periodic international normalized ratio (INR) control, only 19 (9.4%) remained after 1 year. Our study revealed inadequate anticoagulation therapy in elderly patients, probably because most patients refused warfarin therapy because they could not control their INR. Moreover, significantly more rural residents than urban residents refused therapy (48 vs. 22; p < 0.05). Doctors underprescribed anticoagulants because they feared hemorrhagic complications in their patients.

Conclusion: The results of the present study showed that anticoagulants were underprescribed at the outpatient stage in centers of family medicine in our country. The main drug of choice for specialists remains warfarin, which only provides adequate therapy in a small number of patients (9.4%).
ANCA Associated vasculitis- A case of microscopic polyangiitis with proliferative glomerulonephritis
Authors: Akshaya R.C. , Sathyanarayanan R. , Narasimhalu C.R.V. , Sulochana Sonti 
Published: October 2021

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) are a collection of diseases, characterised by destruction and inflammation of small and medium vessels. Microscopic Polyangiitis (MPA) is part of an ANCA-associated vasculitis (AAV).The clinical signs diverge and disturba number of organs such as the kidneys, lungs, stomach and intestine. Skin manifestations such as purpuric, urticarial, nodular, ulcerative, livedoid and necrotic skin lesions were common as in other vaso-occlusive disorder. Morphology and added features aid the diagnostic approach. Here, we report a diagnostically challenging case of microscopic polyangiitis with progressive glomerulonephritis.
Model simulations of arctic biogeochemistry and permafrost extent are highly sensitive to the implemented snow scheme in LPJ-GUESS
Authors: Pongracz Alexandra , Wårlind David , Miller Paul A. , Parmentier Frans-Jan W. 
Published: October 2021

Abstract. The Arctic is warming rapidly, especially in winter, which is causing large-scale reductions in snow cover. Snow is one of the main controls on soil
thermodynamics, and changes in its thickness and extent affect both permafrost thaw and soil biogeochemistry. Since soil respiration during the cold
season potentially offsets carbon uptake during the growing season, it is essential to achieve a realistic simulation of the effect of snow cover on
soil conditions to more accurately project the direction of arctic carbon–climate feedbacks under continued winter warming. The Lund–Potsdam–Jena General Ecosystem Simulator (LPJ-GUESS) dynamic vegetation model has used – up until now – a single layer snow scheme,
which underestimated the insulation effect of snow, leading to a cold bias in soil temperature. To address this shortcoming, we developed and
integrated a dynamic, multi-layer snow scheme in LPJ-GUESS. The new snow scheme performs well in simulating the insulation of snow at hundreds of
locations across Russia compared to observations. We show that improving this single physical factor enhanced simulations of permafrost extent
compared to an advanced permafrost product, where the overestimation of permafrost cover decreased from 10 % to 5 % using the new snow
scheme. Besides soil thermodynamics, the new snow scheme resulted in a doubled winter respiration and an overall higher vegetation carbon content. This study highlights the importance of a correct representation of snow in ecosystem models to project biogeochemical processes that govern climate
feedbacks. The new dynamic snow scheme is an essential improvement in the simulation of cold season processes, which reduces the uncertainty of
model projections. These developments contribute to a more realistic simulation of arctic carbon–climate feedbacks.
Southern Ocean bottom-water cooling and ice sheet expansion during the middle Miocene climate transition
Authors: Leutert Thomas J. , Modestou Sevasti , Bernasconi Stefano M. , Meckler A. Nele 
Published: October 2021

Abstract. The middle Miocene climate transition (MMCT), around 14 Ma, was associated with a significant climatic shift, but the
mechanisms triggering the event remain enigmatic. We present a clumped isotope (Δ47) bottom-water temperature (BWT) record from 16.0 to
12.2 Ma from Ocean Drilling Program (ODP) Site 747 in the Southern Ocean and compare it to existing BWT records from different
latitudes. We show that BWTs in the Southern Ocean reached 8–10 ∘C during the Miocene climatic optimum. These high BWT values indicate considerably warmer bottom-water conditions than today. Nonetheless, bottom-water δ18O (calculated from foraminiferal δ18O and Δ47) suggests substantial amounts of land ice throughout the interval of the study. Our dataset further demonstrates that BWTs at Site 747 were variable with an overall cooling trend across the MMCT. Notably, a cooling of around 3–5 ∘C preceded the stepped main increase in benthic δ18O, interpreted as global ice volume expansion, and appears to have been followed
by a transient bottom-water warming starting during or slightly after the main ice volume increase. We speculate that a regional freshening of the
upper water column at this time may have increased stratification and reduced bottom-water heat loss to the atmosphere, counteracting global cooling
in the bottom waters of the Southern Ocean and possibly even at larger scales. Feedbacks required for substantial ice growth and/or tectonic
processes may have contributed to the observed decoupling of global ice volume and Southern Ocean BWT.
An 18S V4 rRNA metabarcoding dataset of protist diversity in the Atlantic inflow to the Arctic Ocean, through the year and down to 1000 m depth
Authors: Egge Elianne , Elferink Stephanie , Vaulot Daniel , John Uwe , Bratbak Gunnar , Larsen Aud , Edvardsen Bente 
Published: October 2021

Abstract. Arctic marine protist communities have been understudied due to challenging sampling conditions, in particular during winter and in deep waters. The aim of this study was to improve our knowledge on Arctic protist diversity through the year, in both the epipelagic (< 200 m depth) and mesopelagic zones (200–1000 m depth). Sampling campaigns were performed in 2014, during five different months, to capture the various phases of the Arctic primary production: January (winter), March (pre-bloom), May (spring bloom), August (post-bloom), and November (early winter). The cruises were undertaken west and north of the Svalbard archipelago, where warmer Atlantic waters from the West Spitsbergen Current meet cold Arctic waters from the Arctic Ocean. From each cruise, station, and depth, 50 L of seawater was collected, and the plankton was size-fractionated by serial filtration into four size fractions between 0.45–200 µm, representing picoplankton (0.45–3 µm), small and large nanoplankton (3–10 and 10–50 µm, respectively), and microplankton (50–200 µm). In addition, vertical net hauls were taken from 50 m depth to the surface at selected stations. The net hauls were fractionated into the large nanoplankton (10–50 µm) and microplankton (50–200 µm) fractions. From the plankton samples DNA was extracted, the V4 region of the 18S rRNA-gene was amplified by polymerase chain reaction (PCR) with universal eukaryote primers, and the amplicons were sequenced by Illumina high-throughput sequencing. Sequences were clustered into amplicon sequence variants (ASVs), representing protist genotypes, with the dada2 pipeline. Taxonomic classification was made against the curated Protist Ribosomal Reference database (PR2).
Altogether, 6536 protist ASVs were obtained (including 54 fungal ASVs). Both ASV richness and taxonomic composition varied between size fractions, seasons, and depths. ASV richness was generally higher in the smaller fractions and higher in winter and the mesopelagic samples than in samples from the well-lit epipelagic zone during summer. During spring and summer, the phytoplankton groups diatoms, chlorophytes, and haptophytes dominated in terms of relative read abundance in the epipelagic zone. Parasitic and heterotrophic groups such as Syndiniales and certain dinoflagellates dominated in the mesopelagic zone all year, as well as in the epipelagic zone during the winter. The dataset is available at https://doi.org/10.17882/79823 (Egge et al., 2014).
Adsorption of methylene blue dye by different methods of obtaining shrimp residue chitin
Authors: Otto Iliane Muller , Morselli Luiza Beatriz Gamboa Araújo , Bunde Dienifer Aline Braun , Pieniz Simone , Quadro Maurízio Silveira , Andreazza Robson 
Published: October 2021

The textile industry, very important for the world economy, generates an effluent containing dyes, and which, when discarded in water bodies without proper treatment, can cause impacts to human health and the environment. One of these widely used dyes is methylene blue, whose characteristics are high solubility in water and its toxic potential, and which effects range from eye irritations, nausea, vomiting and even mental confusion. Among the potential adsorbents of this dye is chitin, which is a biopolymer extracted from the shrimp exoskeleton. Aiming at the development of a low-cost adsorbent material with potential use in the textile effluent treatment industry, the ability to remove methylene blue dye by shrimp residue chitin, obtained by eleven different methodologies, was verified. The three most efficient treatments reached approximately 75% of dye removal, proving the high adsorption power of shrimp residue. In addition to providing technological development of materials, the research brings socioeconomic benefits to the fishermen’s colony with the use of shrimp residue for the adsorption of other waste from the textile industry, contributing to the sustainability of both activities and reducing the environmental impact.
PEMODELAN KAWASAN PASAR SOUVENIR DI DESA TOMOK (Objek Kasus : Desa Wisata Tomok, Kabupaten Samosir, Sumatera Utara)
Authors: Sitohang Ida Nova , Pakpahan Raimundus , Silitonga Shanty 
Published: October 2021

The tourist market or souvenir shop is a place of sale and purchase transactions in tourist areas that sellÂ merchandise typical of the tourist attraction. The tourist market can be classified into the traditional marketÂ according to the physical, time, area of activities and goods traded. The tourist market can also be classified as aÂ traditional market according to its function as a culture that is a market that has multiple roles, not only acting asÂ a meeting place between sellers and buyers but the market also has a function as a meeting place for culturesÂ brought by each of them who utilize the market. Trading is one of the economic activities of the Tomok tourismÂ village community to meet the needs of the community. Based on the condition of the souvenir shop building,Â there are many variations in terms of size, shape and ownership of the shop. One type of merchandise isÂ souvenir as one of the facilities in Tomok village tourist attraction. For this reason the importance of providingÂ the right model in the souvenir market area in the village of Tomok in order to increase the high tourist arrivalsÂ of tourist taxis. Simulation and modeling research strategies are a research that using imitation models of aÂ particular process or system that will be examined / tested through a simulation process, both scientific andÂ man-made phenomena. The benefit of this research is to find a model of the souvenir market area in the TomokÂ tourism village that meets the criteria of market structuring.
STUDI PERBANDINGAN ARSITEKTUR TRADISIONAL ANGKOLA DENGAN ARSITEKTUR TRADISIONAL BATAK TOBA DITINJAU DARI STRUKTUR BANGUNAN
Authors: Giawa Wengky Billy Putra , Pakpahan Raimundus , Yulianto Yulianto 
Published: October 2021

The Batak are the majority in North Sumatra. The Batak tribe even has another sub-tribe, namely TobaÂ Â Batak, Karo Batak, Simalungun Batak, Mandailing Batak and Angkola Batak. Every Batak tribe has its ownÂ Â distinctive culture and identity. Batak tribes have traditional buildings which are traditional BatakÂ Â architectural identities. The diversity of the Batak tribe caused the phenomenon of visual aspect equality inÂ Â traditional buildings because of the effects of secession and cultural integration. The Toba BatakÂ Â architecture has the concept of a stilt house and pointed gable construction in both directions and a pegÂ and pen structure system is evidence of similarities with Angkola Batak architecture. Angkola Bataks are part of the Batak tribe. Angkola Batak is a tribe in the area of South Tapanuli. The Toba Batak is the center of the Batak culture. The Toba Batak has one of the traditional Sopo buildings, namely Sopo. Sopo functions as a barn, but also an art venue and meeting place. Angkola Batak has one traditional building that represents the traditional architecture of the Angkola Batak namely Sopo Godang. Serves as a meeting place for the king and the people. It is a place where tradition is based on Dalihan Na Tolu which produces consensus and mutual agreement (The King and People). Sopo Godang is a part of traditional Batak architecture that needs to be preserved. The benefit of this study is to collect data on traditional Angkola Batak architecture and data on structures that are characteristic of the Angkola Batak
KAJIAN SKALA PADA BANGUNAN TRADISIONAL ANGKOLA (Studi Kasus : Museum GKPA, Silangge)
Authors: Sitanggang Fernanda , Silitonga Shanty , Napitupulu Putri P 
Published: October 2021

This research raises the scale study of traditional angkola buildings with a case study of the GKPAÂ Museum, Silangge. This building consists of the elements making up the space, both indoor and outdoor.Â The building blocks in the building include: the head of the building (ni orbo horns, closed capillaries,Â dadap na tolu, and lisplank), the building body (doors, windows, vents, and poles), and the legs of theÂ building (foundations, columns, and stairs). While the building elements outside the building include:Â buildings with supporting functions (Debora orphanage and Debora orphanage study room), DeboraÂ orphanage field, and some vegetation around the Angkola Museum. The scale that will be examined in thisÂ study is the human scale (human as a benchmark) of the elements forming the outer space of traditionalÂ Angkola buildings. The scale study will be carried out by analyzing the human scale of the building with aÂ predetermined observation point. This study was classified in research that uses descriptive methods withÂ qualitative analysis. Data analysis with descriptive analysis techniques that use benchmarks. EvaluationÂ research that aims to assess the extent to which the variables studied are in accordance withÂ predetermined benchmarks. The benefit of this research is finding a scale study found in Angkola'sÂ traditional building, whether the building is classified as good with the scale of the outer space that existsÂ in the elements of the building's outer space.
Nivel de conocimiento electrocardiográfico sobre bradi y taquiarritmias y calidad de resucitación cardiopulmonar en estudiantes de medicina 2018
Authors: Cairol Andres , Morún Vargas Wendy , Loaiza Sáenz Luis Felipe , Segura Pérez Edward , Navarro Fallas Tania 
Published: October 2021

El reconocimiento del electrocardiograma (ECG) en el servicio de emergencias plantea un reto y en el contexto de la academia aún más. En este estudio, se sometió a estudiantes que cursaron emergencias médicas en el año 2018 en la UNIBE al reconocimiento de trazos electrocardiográficos y conceptos básicos de calidad de la reanimación cardiopulmonar; como factor diferenciador los estudiantes del III cuatrimestre recibieron 3 horas de sesión de simulación clínica, en comparación con los demás estudiantes de los cuatrimestres restantes. No se encontraron diferencias significativas en el reconocimiento de los trazos con 3 horas de simulación, también se evidenció que solo el 51 % de los ritmos se interpretaron de manera correcta, lo cual demuestra una falencia en este tema en específico. Los ritmos que más se identificaron fueron los ventriculares y la fibrilación atrial, en contra parte los de menor reconocimiento fueron los sinusales y los ritmos lentos. Se recomienda ampliar la cantidad de tiempo dedicado a la simulación y reorientar la enseñanza, estudio y evaluación de este tema, con el fin de demostrar a futuro los beneficios de la simulación clínica.
Evaluation of linear and nonlinear models for temperature driven development of Spodoptera litura (Fabricius) on soybean crop
Authors: Y.G. PRASAD  , M. GAYATHRI  , V. SAILAJA  , M. PRABHAKAR  , G.RAMACHANDRA RAO  , G. REKHA  , S. VENNILA  
Published: October 2021

The tobacco caterpillar, Spodoptera litura, a major pest of soybean in India is under surveillance in all soybean growing areas in Maharashtra in order to issue alerts to farmers and prevent economic losses. In this context, two linear models were fitted to developmental data of S. litura life stages reared on soybean at five constant temperatures viz. 15, 20, 25, 30 and 35°C through laboratory experiments. Optimum temperature for development (Topt) and upper temperature threshold (Tmax) were estimated from three nonlinear models by additionally including developmental response at >35°C. Topt estimates for the total immature development were 34.5°C (Lactin-2), 33.7°C (Briere-1) and 33.2°C (Simplified Beta type function) while Tmax estimates were in the range of 38 to 40°C. Application of a thermodynamic non-linear model (Optim SSI) gave estimate ofintrinsic optimum temperature (Tφ) for development of egg (28.3°C), larva (27.5°C) and pupal stage (30.3°C). The phenology model of S. litura on soybean based on estimated developmental threshold temperatures and thermal constants was validated using available field surveillance data to facilitate informed pest management decisions.
Assessment and monitoring of drought in Chitradurga district of Karnataka using different drought indices
Authors: S. SRIDHARA  , G.M. CHAITHRA  , PRADEEP GOPAKKALI  
Published: October 2021

Drought is a natural disaster due to less precipitation than the normal that can occur irrespective of climate regimes. Impact assessment of drought and monitoring are the most important mitigation stratregies to combat the drought effects. As the single index cannot assess all the drought conditions, in the present study multi-variate indices approach has been used to assess and monitor drought. Five indices were assessed using precipitation data such as deciles index (DI), percent normal (PN), China-Z index (CZI), Z-Score index (ZSI) and standardized precipitation index (SPI). Monthly total precipitation data was used to calculate drought events occurred during the period 1967–2017 in different talukas of Chitradurga district of Karnataka, India. The assessment revealed that SPI, CZI and ZSI performance was similar in identifying drought. PN was very much responsive for the rainfall events that occurred during the particular year however, it exhibited variations in dry conditions. DI was not that much satisfactory in identifying drought conditions. Among the five indices assessed, SPI seems to be the best indicator to predict the drought onset than the other four drought indices. Therefore SPI can be recommended for assessing and monitoring the drought in Chitradurga district of Karnataka, India.
Desarrollo del pensamiento crítico a través del cine como recurso didáctico
Authors: Monsalve Lorente Laura , Ruiz Romero María José 
Published: October 2021

Objetivo del estudio: El propósito de este trabajo es analizar, clarificar y visibilizar los diferentes usos del cine en población adolescente, dotando de herramientas al profesorado con una extensa propuesta de materiales en formato de nueve películas y series. Así mismo, se pretende describir una serie de competencias que potencien el pensamiento crítico del alumnado perteneciente a esta etapa, con el fin de favorecer una sociedad más plural y justa.
Diseño/metodología/enfoque: Se ha seguido una metodología cualitativa, en la que se realiza una revisión y búsqueda documental. El análisis se ha basado en tres ejes: una revisión y búsqueda documental sobre la utilización del cine como recurso educativo en las etapas de secundaria, selección y análisis de nueve películas/series y la descripción de las competencias que promueven para utilizar el cine como herramienta de aprendizaje basado en valores y concienciar al alumnado de secundaria sobre los derechos que poseen, sus libertades, la diversidad cultural, etc., para favorecer una sociedad más plural y justa.
Resultados: Es un hecho que dependiendo del uso que se le dé al cine se consiga educar en valores y concienciar al alumnado perteneciente a la etapa de Educación Secundaria Obligatoria (ESO) sobre sus derechos, sus libertades, etc. Por ello, el pensamiento crítico juega un papel primordial en la interpretación del contenido audiovisual que se exponga al grupo-clase. En la realización del presente trabajo se ha podido comprobar las posibilidades del cine en las aulas, dejando abiertas una gran cantidad de propuestas para líneas futuras, como el análisis de otros bloques y temáticas.
Originalidad/contribución: Este texto contribuye al fomento de trabajar el pensamiento crítico a través del cine en las aulas de Educación Secundaria Obligatoria. Se demuestra las posibilidades que tiene el cine como recurso pedagógico para educar en valores a través de contenido audiovisual concienciado al alumnado sobre sus derechos y libertades.
Clasificación JEL: D83; I20; I21