bluuebunny/crossref_metadata_2025_split huggingface dataset:
A relationship between bias, lean tools, and waste
Authors: Purushothaman Mahesh Babu , Seadon Jeff , Moore Dave 
Published: December 2021

Purpose
This study aims to highlight the system-wide potential relationships between forms of human bias, selected Lean tools and types of waste in a manufacturing process.

Design/methodology/approach
A longitudinal single-site ethnographic case study using digital processing to make a material receiving process Lean was adopted. An inherent knowledge process with internal stakeholders in a stimulated situation alongside process requirements was performed to achieve quality data collection. The results of the narrative analysis and process observation, combined with a literature review identified widely used Lean tools, wastes and biases that produced a model for the relationships.

Findings
The study established the relationships between bias, Lean tools and wastes which enabled 97.6% error reduction, improved on-time accounting and eliminated three working hours per day. These savings resulted in seven employees being redeployed to new areas with delivery time for products reduced by seven days.

Research limitations/implications
The single site case study with a supporting literature survey underpinning the model would benefit from testing the model in application to different industries and locations.

Practical implications
Application of the model can identify potential relationships between a group of human biases, 25 Lean tools and 10 types of wastes in Lean manufacturing processes that support decision makers and line managers in productivity improvement. The model can be used to identify potential relationships between forms of human biases, Lean tools and types of wastes in Lean manufacturing processes and take suitable remedial actions. The influence of biases and the model could be used as a basis to counter implementation barriers and reduce system-wide wastes.

Originality/value
To the best of the authors’ knowledge, this is the first study that connects the cognitive perspectives of Lean business processes with waste production and human biases. As part of the process, a relationship model is derived.
Investigating the role of employee psychological well-being and psychological empowerment with relation to work engagement and sustainable employability
Authors: Rahi Samar 
Published: December 2021

PurposeThis study aims to gain insight into how employee psychological and human resource (HR) practices impact employee work engagement behavior. In addition to that, the research model of this study has tested the moderating relationship of affective employee commitment between employee work engagement and sustainable employability.Design/methodology/approachThe research model is empirically tested with data set of 311 responses retrieved from an employee working in private organizations. Sample size of this study is computed with prior power analysis. Data were analyzed with partial least square-based structural equation modeling (SEM).FindingsFindings of the SEM revealed that altogether psychological well-being, psychological empowerment, HR compensation, HR training, transformational leadership and job enrichment have explainedR266.1% variance in employee work engagement. Concerning individual impact size psychological well-being has shown medium level effect size (f2) in measuring employee work engagement. However, all other exogenous variables have shown a small effect in determining employee work engagement. The moderating effect of commitment is confirmed in such a way that the relationship between employee work engagement and sustainable employability will be higher when affective commitment is higher.Practical implicationsThis research has synthesized HR literature into four core dimensions of HR practices and, hence contributes to HR literature. Similarly, this research contributes to well-being theory while integrating employee psychological well-being into the research model. For HR practitioners this research revealed that psychological well-being, psychological empowerment, affective employee commitment, transformational leadership, HR compensation and HR training are core factors, which influence employee behavior toward work engagement and sustainable employability.Originality/valueThe current research is unique as it investigates sustainable employability phenomenon with an integrated research model that combines employee psychological and HR factors. The concept of sustainable employability is less studied, and therefore this research fills the research gap in this context.
Impact of media multitasking on executive function in adolescents: behavioral and self-reported evidence from a one-year longitudinal study
Authors: Luo Jiutong , Yeung Pui-Sze , Li Hui 
Published: December 2021

PurposeThe longitudinal impact of media multitasking on the development of executive function has been understudied, as most of the existing studies are cross-sectional. This longitudinal study addresses this research gap and uses multiple measures, i.e. behavioral and self-reported, to explore the impact of media multitasking on the executive function of Chinese adolescents.Design/methodology/approachThis study followed 99 Chinese adolescents (Mage = 14.41, SD = 1.10; 42 boys and 57 girls) for one year using both behavioral (2-back, Stroop Color and Number-letter tasks) and self-reported (questionnaire) measures. The adolescents were categorized as either heavy/high media multitaskers (HMMs; 19 boys and 29 girls) or light/low media multitaskers (LMMs; 23 boys and 28 girls). They were tested at baseline, 6 months later and 12 months later.FindingsThe results indicated that the accuracy scores for all cognitive tasks differed with age, but the switch-cost in the shifting task and the self-reported measures of executive function did not. And there were consistent differences between the HMMs and LMMs in the self-reported measures and 2-back accuracy. However, the interaction effect was found only in shifting ability, indicating a decline in the LMMs' self-reported problematic shifting behavior in daily life.Originality/valueThis study used behavioral and self-reported measures to confirm the longitudinal impact of media multitasking on executive function. The impact of media multitasking on executive function is more apparent in daily-life behavior than in cognitive task performance.
Elastic properties and litho‐fluid facies estimation from pre‐stack seismic data through bidirectional long short‐term memory networks
Authors: Aleardi Mattia 
Published: December 2021

ABSTRACTOne of the main goals of pre‐stack seismic inversion is the estimation of elastic properties (i.e. P‐, S‐ wave velocities and density) and litho‐fluid classes in the investigated area. To this end, many inversion strategies have been proposed, but the most popular is based on a two‐step inversion approach: First, elastic properties are inferred from pre‐stack data, and then a classification algorithm is used to convert the outcomes of the first stage into litho‐fluid facies. In this work, we propose an alternative approach based on recurrent neural networks. We train two bidirectional long short‐term memory networks to predict the inverse mappings from pre‐stack seismic data to elastic properties, and litho‐fluid classes. In the elastic inversion, we also use a Monte Carlo simulation approach to properly propagate onto the model space both the uncertainties related to noise contamination in the data and to the modelling error introduced by the network approximation. One crucial aspect of any machine‐learning inversion strategy is the definition of an appropriate training set. In this case, the models forming the training and validation examples are drawn according to a previously defined elastic and facies prior models derived from actual well log recordings. In particular, we assume a Gaussian‐mixture elastic prior, and we also take into account the uncertainties affecting the estimation of the transition probabilities of facies. We invert each seismic gather independently, and in this context, the generation of the training set, and the learning process can be accomplished with a very limited computational effort on a common notebook. Once trained, the networks estimate the elastic properties, the litho‐fluid facies and the related uncertainties from the pre‐stack data in near real‐time. Synthetic and field data inversions are used to validate the proposed method. The network predictions are also benchmarked against the outcomes of a more standard two‐step approach that combines a linear elastic inversion and a subsequent point‐wise Bayesian classification. Our results demonstrate that the implemented algorithm guarantees more accurate elastic property estimations and facies predictions than the standard inversion strategy. In particular, the predictions provided by the long short‐term memory network are less affected by erroneous assumptions on the noise statistics and prior model and by errors in the estimated source wavelet.
Ultrasound‐guided multiple‐injection costotransverse block for mastectomy and primary reconstructive surgery. A study protocol
Authors: Holm Ulrik H. U. , Andersen Christian H. S. , Hansen Christian K. , Tanggaard Katrine , Børglum Jens , Nielsen Martin Vedel 
Published: December 2021

AbstractBackgroundPost‐operative pain amelioration following breast cancer surgery is inconsistent. The novel multiple‐injection costotransverse block (MICB) mimics the thoracic paravertebral block by possible anaesthetising the ventral rami of the thoracic spinal nerves and the sympathetic trunk. Proof of concept has been determined in a cadaveric study and needs further clinical testing.MethodsThis double‐blinded, randomised and placebo‐controlled study investigates the efficacy of the ultrasound‐guided MICB versus placebo in 36 patients undergoing unilateral mastectomy and primary subpectoral reconstruction surgery. Oral pre‐operative medicine is standardised for all patients. Active group is pre‐operatively administered MICB with three injections of each 10 ml of ropivacaine (5 mg/ml). The placebo group is pre‐operatively administered three injections of each 10 ml of saline (0.9%). Standard general anaesthesia is induced and 30 min before emergence 0.2 μg/kg total body weight sufentanil IV, 1 g of paracetamol IV and 4 mg of ondansetron IV (post‐operative nausea and vomiting, PONV, prophylaxis) will be administered. All patients are provided with a patient‐controlled analgesia pump with morphine. The primary aim is total morphine consumption in the first 24 post‐operative hours. Secondary aims are pain intensity, duration of the block, patient satisfaction, side effects, time to ambulation, time to discharge, and quality of recovery.DiscussionRecruitment began in November 2019 and is expected to finish ultimo 2021. Results are expected to be published in an international peer‐reviewed medical journal. The results will hopefully provide a substantial contribution to the knowledge of these new ‘intertransverse process blocks’ providing regional anaesthesia of the thoracic wall.
Profiling of extracellular vesicle‐bound miRNA to identify candidate biomarkers of chronic alcohol drinking in nonhuman primates
Authors: Lewis Sloan A. , Doratt Brianna , Sureshchandra Suhas , Pan Tianyu , Gonzales Steven W. , Shen Weining , Grant Kathleen A. , Messaoudi Ilhem 
Published: December 2021

AbstractBackgroundLong‐term alcohol drinking is associated with numerous health complications including susceptibility to infection, cancer, and organ damage. However, due to the complex nature of human drinking behavior, it has been challenging to identify reliable biomarkers of alcohol drinking behavior prior to signs of overt organ damage. Recently, extracellular vesicle‐bound microRNAs (EV‐miRNAs) have been found to be consistent biomarkers of conditions that include cancer and liver disease.MethodsIn this study, we profiled the plasma EV‐miRNA content by miRNA‐Seq from 80 nonhuman primates after 12 months of voluntary alcohol drinking.ResultsWe identified a list of up‐ and downregulated EV‐miRNA candidate biomarkers of heavy drinking and those positively correlated with ethanol dose. We overexpressed these candidate miRNAs in control primary peripheral immune cells to assess their potential functional mechanisms. We found that overexpression of miR‐155, miR‐154, miR‐34c, miR‐450a, and miR‐204 led to increased production of the inflammatory cytokines TNFα or IL‐6 in peripheral blood mononuclear cells after stimulation.ConclusionThis exploratory study identified several EV‐miRNAs that could serve as biomarkers of long‐term alcohol drinking and provide a mechanism to explain alcohol‐induced peripheral inflammation.
PolyI:C attenuates transforming growth factor‐β signaling to induce cytostasis of surrounding cells by secreted factors in triple‐negative breast cancer
Authors: Tamura Yusuke , Tsutsumi Shuichi , Miyazono Kohei , Koinuma Daizo 
Published: December 2021

AbstractThe activation of RIG‐I‐like receptor (RLR) signaling in cancer cells is widely recognized as a critical cancer therapy method. The expected mechanism of RLR ligand‐mediated cancer therapy involves the promotion of cancer cell death and strong induction of interferon (IFN)‐β that affects the tumor microenvironment. We have recently shown that activation of RLR signaling in triple‐negative breast cancer cells (TNBC) attenuates transforming growth factor‐β (TGF‐β) signaling, which partly contributes to the promotion of cancer cell pyroptosis. However, the consequences of suppression of TGF‐β signaling by RLR ligands with respect to IFN‐β‐mediated tumor suppression are not well characterized. This study showed that transfection of a typical RLR ligand polyI:C in cancer cells produces significant levels of IFN‐β, which inhibits the growth of the surrounding cancer cells. In addition, IFN‐β‐induced cell cycle arrest in surrounding cancer cells was inhibited by the expression of constitutively active Smad3. Constitutively active Smad3 suppresses IFN‐β expression through the alleviation of IFN regulatory factor 3 binding to the canonical target genes, as suggested by ChIP sequencing analysis. Based on these findings, a new facet of the protumorigenic function of TGF‐β that suppresses IFN‐β expression is suggested when RLR‐mediated cancer treatment is used in TNBC.
The post‐war generation remembers: A mixed‐method study exploring children’s attitudes towards World War II commemoration
Authors: Mitima‐Verloop Huibertha B. , Boelen Paul A. , Mooren Trudy T. M. 
Published: December 2021

AbstractThis study investigated how children, a post‐war generation without direct connection to war, relate to the commemoration of World War II (WWII). Seven group interviews were held among pupils in the Netherlands, aged 9 to 18 (n = 55) and, subsequently, questionnaires were administered to other pupils (n = 374). Results revealed that children are affected by the collective narrative of WWII, and connect to commemoration on a social and emotional level. Comprehension, tangibility, inclusiveness and a right atmosphere are key elements to appreciate a commemoration. Insights from this study may help societies practice more appealing remembrances with post‐war generations.
Rational Redundancy in Referring Expressions: Evidence from Event‐related Potentials
Authors: Tourtouri Elli N. , Delogu Francesca , Crocker Matthew W. 
Published: December 2021

AbstractIn referential communication, Grice's Maxim of Quantity is thought to imply that utterances conveying unnecessary information should incur comprehension difficulties. There is, however, considerable evidence that speakers frequently encode redundant information in their referring expressions, raising the question as to whether such overspecifications hinder listeners’ processing. Evidence from previous work is inconclusive, and mostly comes from offline studies. In this article, we present two event‐related potential (ERP) experiments, investigating the real‐time comprehension of referring expressions that contain redundant adjectives in complex visual contexts. Our findings provide support for both Gricean and bounded‐rational accounts. We argue that these seemingly incompatible results can be reconciled if common ground is taken into account. We propose a bounded‐rational account of overspecification, according to which even redundant words can be beneficial to comprehension to the extent that they facilitate the reduction of listeners’ uncertainty regarding the target referent.
Trends in an emerging artisanal fishery of the African cyprinid Rastrineobola argentea in Lake Nabugabo, Uganda
Authors: Groves Veronica , Sharpe Diana M. T. , Nkalubo Winnie , Chapman Lauren J. 
Published: December 2021

AbstractFishing pressure can have strong impacts on fish populations, driving declines in abundance and, occasionally, changing life history traits. However, much of our current understanding of these phenomena derives from studies conducted decades or even centuries after the onset of fishing. Newly established fisheries provide an excellent opportunity to understand this critical early phase. Temporal trends in catch data and life history traits of the cyprinid fish Rastrineobola argentea (Pellegrin), now the target of a burgeoning artisanal fishery in Lake Nabugabo, Uganda, were analysed. Results showed that the R. argentea fishery intensified and became more selective during the first decade since its establishment (2008–2019), while catch‐per‐unit‐effort of R. argentea (fisheries‐independent abundance) at repeatedly sampled sites in the lake decreased over this same time period. Size‐adjusted egg volume and ovary mass increased significantly over the time period, which may reflect a density‐dependent response to a fisheries‐induced population decline.
Salvage of infected tunneled hemodialysis catheters using 70% ethanol lock solution: A brief report
Authors: Visweswaran Kasi , Ravi Ranjani , Daniel David Jasper , Krishnaswamy Sampathkumar , Akhil Remyasri 
Published: December 2021

AbstractTunneled hemodialysis catheters are the lifeline to patients on maintenance hemodialysis with failed arteriovenous fistulas. However, thrombosis and infection are the main causes of reduced longevity of these accesses. According to IDSA guidelines, catheter‐related infection with Pseudomonas and fungi are absolute indications for catheter removal. Considering the cost and difficulties in catheter replacement, for those in whom all accesses are exhausted, retaining the same catheter may be lifesaving. We would like to present two patients in whom, 70% ethanol instillation was used to eradicate infection with these organisms as confirmed by repeat cultures post procedure. Hemodialysis is being successfully continued through the same catheter.
Administration of adipose stromal vascular fraction attenuates acute rejection in donation after circulatory death rat renal transplantation
Authors: Wang Xinning , Zhou Changcheng , Liu Jingyu , Mao Liang , Yang Tianli , Hong Xi , Jiang Nan , Jia Ruipeng 
Published: December 2021

ObjectiveStem cell therapy represents a new approach to induce immune tolerance in solid organ transplantation. However, the time‐consuming process of stem cell expending limits the range of stem cell treatment. Uncultured adipose stromal vascular fraction is considered an attractive cell source for cell‐based therapy. This study aimed to evaluate the effect of stromal vascular fraction on the immune system in donation after circulatory death rat renal transplantation.MethodsStromal vascular fraction cells and splenocytes were co‐cultured to evaluate the effect of stromal vascular fraction on splenocyte proliferation and viability. Sprague–Dawley rats were used as donors. and Wistar rats as recipients to establish a donation after a circulatory death rat renal transplantation model. Warm ischemia time was 5 min. Stromal vascular fraction was administered in the rat model following the intra‐arterial route. The spleens and grafts of recipients were harvested on days 1, 3 and 7 post‐transplantation for assessing acute rejection, infiltration of inflammatory cells, indoleamine 2, 3‐dioxygenase expression and T‐cell frequency in the spleen.ResultsStromal vascular fraction could inhibit proliferation and induce apoptosis of splenocytes in vitro (P < 0.05). The administration of stromal vascular fraction could significantly reduce acute rejection and infiltration of CD8+ T cells and mononuclear macrophages in grafts, and increase indoleamine 2, 3‐dioxygenase expression (P < 0.05). The frequency of CD8+ T cells decreased, and the frequency of CD25+Foxp3+ regulatory T cells increased in the spleen of the acute rejection + stromal vascular fraction group on day 7 post‐transplantation (P < 0.05).ConclusionAdministration of the adipose stromal vascular fraction could attenuate acute rejection in donation after circulatory death renal transplantation by increasing the ratio of regulatory T cells and enhancing indoleamine 2, 3‐dioxygenase expression.
Evaluation of patient satisfaction for telehealth (telephone and video) in rheumatology outpatients during COVID‐19 pandemic
Authors: Oh Yumi , Hennessey Ashleigh , Young Laurel , Barrett Claire 
Published: December 2021

AbstractBackgroundTelehealth in rheumatology has been a topic of interest for many years, but the COVID‐19 pandemic placed it in the forefront.AimsTo evaluate patient perception of rheumatology telehealth and determine predictive factors for future telehealth acceptability.MethodsA questionnaire containing 30 questions was sent to public and private rheumatology patients who attended telehealth appointments between April and May 2020. The questionnaire aimed to obtain information on baseline demographics, traditional appointment details, telehealth appointment details and appointment satisfaction using a 5‐point Likert scale. Descriptive statistical analysis was conducted.ResultsThe questionnaire was sent to 1452 patients, of whom 494 (34%) patients responded. More than 70% of responses indicated overall satisfaction in specialist care through telehealth, and 88.7% perceived this suitable during a pandemic. Less than 50% of patients were agreeable for future telehealth either through telephone or video conference after the pandemic is over. Higher odds ratio for future telehealth acceptability was associated with visual impairment, perceived cost‐effectiveness and previous time lost at work for a face‐to‐face appointment.ConclusionDuring the unprecedented time of the pandemic, telehealth appointments (telephone/video) assisted in providing ongoing patient care remotely, with high level of satisfaction seen in this study. The patient's experience and perception of telehealth was strongly influenced by financial incentives, and certain subgroups of patients were more accepting for future telehealth appointments. Nevertheless, low level of future telehealth acceptability also highlighted the potential dissatisfaction among patients in telehealth compared with the traditional appointments.