bluuebunny/crossref_metadata_2025_split huggingface dataset:
МОДЕЛЬ ОЦЕНКИ ДИНАМИКИ ЗРЕЛОСТИ ПРОМЫШЛЕННЫХ ЭКОСИСТЕМ
Authors: Dudareva Olga V. , Dudarev Dmitry N. , Goncharov Alexander Y. 
Published: May 2021

Переход на экономику, устроенную по принципу экосистем, является сверхзадачей Российской Федерации. Стимулирование развития всеохватной и устойчивой промышленности и дальнейшие инвестиции в материальную инфраструктуру, инновации и научные исследования имеют принципиальное значение для долгосрочного экономического развития. Развитие промышленной экологии на основе кросс-отраслевого взаимодействия позволило сформулировать предпосылки и необходимость перехода от традиционных промышленных систем к более интегрированным моделям, подобным биологическим экосистемам. Основным катализатором такой трансформации промышленных систем в экосистемы явилась технологическая динамика. Промышленная экосистема не имеет четких границ и требует специфического набора индикаторов для оценки ее зрелости. Отсутствуют аналоги для сравнения промышленных экосистем, а единственным способом установления целевых значений показателей является опрос участников. Тем не менее, концепция оценки зрелости применима и авторы операционализируют ее путем внедрения ряда индикаторов, позволяющих определить этап развития экосистемы. Подход основан на методологии оценки цифровой зрелости организации Центра перспективных управленческих решений (ЦПУР).
Цель – определение способов и приемов оценки уровня цифровой зрелости промышленной экосистемы.
Метод или методология проведения работы: использовались экономико-математические методы, а также статистические методы анализа.
Результаты: модель позволяет решить важную задачу: оценить текущее состояние экосистемы и выявить проблемы, которые не позволяют ей достичь целевого уровня.
Область применения результатов: полученные результаты целесообразно применять экономическими субъектами, осуществляющими промышленную деятельность.
Shaming Microloan Delinquents: Evidence from a Field Experiment in China
Authors: Bu Di , Liao Yin 
Published: May 2021

We study the effects of village credit information sharing on individual microloan repayment, using a randomized experiment with loan applicants from 40 villages in rural China. In our main treatment, customers received a message on the loan application form that “overdue payment (40 days after each installment due date) will be considered for public disclosure among the village by showing debtors’ names on a blackboard outside the village office of the microlending institution.” On average, this social appeal reduces the share of delinquents and the individual delinquency rate by 18.6% and 5.6% from baseline rates of 79.5% and 15.2%, respectively. The effects appear more pronounced among male and older borrowers. Additional treatments help to benchmark the effect against lender credit information sharing and separate the effects on adverse selection and moral hazard. Mechanism analysis shows that the publicly disclosed “blacklist” of delinquents affects borrowers’ repayment behaviors, partially through borrowers’ fear of losing informal risk insurance from the village society and predominately through public shaming penalties. Overall, these results support that, in traditional societies, social appeals can provide not only pecuniary, but also psychological incentives to improve loan repayment. Psychological incentives, to some extent, have stronger effects. This paper was accepted by Gustavo Manso, finance.
Embolisation of Vertebral Artery Damaged Following Cervical Disc Removal
Authors: Johannes Borkert  , Annika Hirte  , Jacobus Reimers  , Nicoline Jochmann  , Sigrid Nikol  
Published: May 2021

Introduction: The incidence of vertebral artery (VA) injury during cervical spine surgery is rare. Even though tamponade is effective in many cases, early consultation of an endovascular team is recommended if bleeding cannot be controlled. We report a case of emergent endovascular embolisation of left VA due to iatrogenic injury during anterior cervical disc removal and fusion. Case: A 47-year-old woman was admitted to our emergency department with serious arterial bleeding from the neck only hours after undergoing anterior cervical disc removal and fusion surgery. She was intubated and mechanically ventilated, however hemorrhage could not be successfully controlled by packing with surgical hemostatic agents. Cranial computed tomography, computed tomography of the cervical spine and CT angiography confirmed the suspected diagnosis of injury to the VA. Emergent endovascular embolisation successfully stopped the bleeding. Occlusion of the vessel was achieved by vascular plugging. The patient was discharged from our hospital 14 days after the intervention, receiving a revision surgery of the cervical spine on the day of embolisation. At the date of discharge she presented without any focal neurological deficit. Conclusion: Pre-operative radiographic imaging of the cervical spine should be used routinely to identify anatomic abnormalities of the vertebral arteries. Endovascular embolisation appears to be effective in treating acute iatrogenic dissection of the vertebral arteries.
Variegate Porphyria Triggered by Acute Hepatitis A Infection
Authors: Daniel Micallef  , Charlton Agius  , Charles Mallia-Azzopardi  , Gerald Buhagiar  , Lawrence Scerri  
Published: May 2021

Background: Variegate porphyria (VP) is a rare disorder of haem biosynthesis. We report a novel association with hepatitis A infection. Patient and methods: A 31-year-old man was diagnosed with acute hepatitis A infection. During recovery, he presented with abdominal pain and a photoaggravated blistering skin eruption. Results: Urine porphyrin precursors were markedly raised with high coproporphyrin III isomer levels. Faecal protoporphyrin levels were markedly increased and a maximum plasma fluorescence emission at 629 nm was noted. Discussion: Acute hepatitis A infection, and the associated metabolic stress exerted on the haem biosynthetic pathway, induced overt presentation of latent VP.
A Case of Fatal Intestinal Infarct Preceded by Recurrent Ischaemic Colitis due to the Enterotoxic Effect of Sodium Polystyrene Sulfonate
Authors: Renato De Vecchis  , Andrea Paccone  
Published: May 2021

Case description: A 64-year-old patient with chronic renal failure and persistent hyperkalaemia not corrected by dialysis, was prescribed sodium polystyrene sulfonate (SPS) at a low dose (30 g/day for 2 days a week during the long interdialytic interval). After 3 months of therapy, the patient developed intense abdominal pain with non-specific colitis identified with a colonoscopy. In addition, the biopsy specimens showed rhomboid SPS crystals in the intestinal mucosa. Fourteen months after discontinuing therapy, the patient again presented with colitis and persistent biopsy finding of SPS crystals. The patient died a few months later due to intestinal infarction. Discussion and conclusion: SPS is a cation exchange resin used to treat hyperkalaemia resistant to dialysis, but may cause inflammation and ischaemia of the colon. In our patient, a short 3-month course of low-dose SPS therapy (without sorbitol, which is used to counter iatrogenic constipation caused by SPS) induced relapsing colitis, which was followed by massive intestinal infarction a few months later. In light of frequent reports of its enterotoxic effects, SPS should be replaced with the new potassium chelators (patiromer and sodium zirconium cyclosilicate).
COVID-19 Induced Pancytopenia in a Major Molecular Response CML patient on Dasatinib: A Case Report and Review of Literature
Authors: Balraj Singh  , Sarah Ayad  , Parminder Kaur  , Vinod Kumar  , Sachin Gupta  , Michael Maroules  
Published: May 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), has caused a global health crisis. COVID-19 can have a multifaceted presentation. A wide range of complications and outcomes can emerge based on the severity and comorbidities of the infected patient. We report a 42-year-old male with past medical history of CML on Dasatinib (in Major Molecular Response) who was diagnosed with COVID-19 and developed pancytopenia. Our case and review of available reports add to the limited literature available regarding COVID-19 in CML.
Severe Complication of Thiopurine Treatment in a Young Woman with Crohn’s Disease
Authors: Michiel PJ Voet  , TGA Calon  , MMC Hendriks  , RM Schreuder  
Published: May 2021

Case Description: TA 28-year old woman receiving thiopurine treatment for Crohn’s disease presented with a systemic primo cytomegalovirus (CMV) infection affecting the gut (colitis), liver (hepatitis), lungs (pneumonitis) and eyes (retinitis). Secondary to this systemic infection, she developed splenomegaly, pancytopenia and lymphadenopathy. Anti-viral treatment resulted in complete resolution of clinical, biochemical and radiological abnormalities within 6 weeks. Conclusion: Early recognition is crucial since CMV infection in a patient receiving thiopurine treatment may result in serious complications.
Azygos Continuation of the Inferior Vena Cava: Potential for Misdiagnosis as Lung Neoplasm
Authors: Sharjeel Shaikh  , Hind Awad  , Anna Kelly  , Tadhg Gleeson  
Published: May 2021

Background: The azygos venous system is an accessory venous pathway supplying an important collateral circulation between the superior and inferior vena cava (IVC). Case summary: We report a case of complicated community-acquired pneumonia with interruption of the IVC with azygos continuation that was misdiagnosed as lung neoplasm. Discussion: The aim of this case report is to emphasize the importance of recognizing an enlarged azygos vein at the confluence with the superior vena cava and in the retrocrural space to avoid misdiagnosis as a right-sided para-tracheal mass. The angiographic features and clinical importance of this condition are discussed.
Coombs-Negative Haemolytic Anaemia, Direct Hyperbilirubinaemia and Splenomegaly: A Rare Amalgam
Authors: Radhika Kulkarni  , Amjad Basheer  , Aziz Khan  
Published: May 2021

Introduction: Epstein-Barr virus (EBV) is notorious for its varied presentation in adults. Reactivation of EBV can occur at any time and is often due to weakened cellular immunity. Case Description: Here we report the case of a young woman with no previous medical history who presented with cholestatic hepatitis, Coombs-negative haemolytic anaemia and splenomegaly. Due to the initial disjointed picture with no other localizing symptoms, she underwent extensive work-up for the same. Discussion: EBV has been associated with many malignancies, autoimmune diseases and chronic fatigue syndrome. EBV causes elevated liver enzymes; however, cholestatic hepatitis is exceedingly rare, with only a few cases reported. Haemolytic anaemia is a common complication of EBV infection and is often Coombs positive. Conclusion: EBV testing should be considered before more invasive and expensive work-up in a patient presenting with multi-systemic abnormalities.
Escola Livre de Dança da Maré: um chão em partilha
Authors: Soter Silvia , Pavlova M. Adriana 
Published: May 2021

O artigo trata da experiência da Escola Livre de Dança da Maré, criada pela artista Lia Rodrigues e pela professora Silvia Soter em parceria com a Redes de Desenvolvimento da Maré. A formação em dança de jovens estudantes tem impacto para além de uma formação técnica e profissional, abrindo possibilidades de futuro e alargando subjetividades. Palavras-chave: Ensino de Dança, Dança, Favela, Jovens
Trânsitos
Authors: De Araújo Inês , Queiroz Tania 
Published: May 2021

O artigo comenta e transcreve trechos da entrevista realizada pelas autoras com o artista indígena Xadalu Tupã Jekupé, relacionando suas intervenções artísticas e seu trânsito entre cidade e aldeias a modos de estabelecer contato entre a arte e seu público através do contágio, gesto que alcança a coletividade inadvertidamente, e contamina essas sociedades.
¿Todas las pestes la peste? Individuo, destino y modernidad en el Diario del año de la peste (1722)
Authors: Martínez Carolina 
Published: May 2021

El artículo examina los efectos de la gran plaga de Londres (1665) tal como fue narrada por Daniel Defoe en Diario del año de la peste (1772) a partir de dos ejes de análisis: las tensiones entre individuo y comunidad en la temprana modernidad y su carácter propedéutico a la luz de los acontecimientos actuales.
Adjusting to university: Perceptions of first-year health professions students
Authors: Malau-Aduli Bunmi S. , Adu Mary D. , Alele Faith , Jones Karina , Drovandi Aaron , Mylrea Martina , Sfera Kornelija , Ross Simone , Jennings Ernest 
Published: May 2021

Background
The transition experience into university can be challenging for health profession students as they are required to rapidly learn diverse and adaptable problem solving skills and advanced reflective thinking processes which are necessary to address complex patient-care problems, particularly in the face of uncertainty within a dynamic and rapidly evolving learning environment.

Methods
A mixed-methods study was conducted to identify factors influencing this transition for first-year medical, dental, and pharmacy students at a regional Australian university. The Student Adaption to College Questionnaire (SACQ) examined participants’ levels of adjustment to university, while Schlossberg’s 4 S transition model was utilised in a framework analysis of the focus group and interview responses.

Results
Complete survey responses were obtained from 198 students, 17 of whom also participated in focus group discussions or interviews. Mean adjustment ratings obtained from the SACQ responses were academic (6.09 ± 1.3) personal-emotional (5.53 ± 1.55), social (6.30 ± 1.38), and institutional attachment (6.96 ± 1.6). These results indicate that the personal and emotional aspects of this transition were more challenging for the students. Analysis of the qualitative data revealed that generally, for these highly motivated health-professions students, dropping out of university was not an option and this had a positive influence on their ability to adjust to their new learning environment. Nonetheless, the transition involved role change; school-leavers were excited about their newly found independence, while for mature-aged students, returning to university allowed them to pursue their lifelong dreams. Adjustment was more challenging for international, mature-aged and female students, with personal and social factors influencing the transition for each of these demographic groups.

Conclusions
To facilitate smooth transition into university, tertiary education institutions must consider tailored on-going support strategies that promote social interaction among students with varied backgrounds and personal characteristics.
The cost-effectiveness of a two-step blood pressure screening programme in a dental health-care setting
Authors: Andersson Helen , Svensson Mikael , Bergh Håkan 
Published: May 2021

Background
Hypertension is one of the largest contributors to the disease burden and a major economic challenge for health-care systems. Early detection of persons with high blood pressure can be achieved through screening and has the potential to reduce morbidity and mortality. We evaluate the cost-effectiveness of an opportunistic hypertension screening programme in a dental-care facility for individuals aged 40–75 in comparison to care as usual (the no-screening baseline scenario).

Methods
A cost-effectiveness analysis (CEA) was carried out from the payer and societal perspectives, and the short-term (from screening until diagnosis has been established) cost per identified case of hypertension and long-term (20 years) cost per quality-adjusted life year (QALY) were reported. Data on the short-term cost were based on a real-world screening programme in which 2025 healthy individuals were screened for hypertension. Data on the long-term cost were based on the short-term outcomes combined with modelling in a Markov cohort model. Deterministic and probabilistic sensitivity analyses were carried out to assess uncertainty.

Results
The short-term analysis showed an additional cost of 4,800 SEK (€470) per identified case of hypertension from the payer perspective and from the societal perspective 12,800 SEK (€1,240). The long-term analysis showed a payer cost per QALY of 2.2 million SEK (€210,000) and from the societal perspective 2.8 million SEK per QALY (€270,000).

Conclusion
The long-term model results showed that the screening model is unlikely to be cost-effective in a country with a well-developed health-care system and a relatively low prevalence of hypertension.
Pharmacist medication review: An integrated team approach to serve home-based primary care patients
Authors: Monzón-Kenneke Michele , Chiang Paul , Yao Nengliang (Aaron) , Greg Mark 
Published: May 2021

Background
Comprehensive medication review is a patient-centered approach to optimize medication use and improve patient outcomes. This study outlines a pilot model of care in which a remote corporate-based clinical pharmacist implemented comprehensive medication reviews for a cohort of medically complex home-based primary care (HBPC) patients.

Method
Ninety-six medically complex patients were assessed for medication-related problems. Data collected on these patients were: number of chronic conditions, number of medications, appropriate indication for each medication, dose appropriateness, drug interactions, recommendations for medication optimization and deprescribing. The number of accepted recommendations by the HBPC practice was analyzed.

Results
On average, the patients were 82 years old and had 13 chronic conditions. They were taking a median of 17 medications. Over a four-month pilot period, 175 medication recommendations were made, and 53 (30.3%) of them were accepted, with most common being medication discontinuation, deprescribing, and dose adjustments. Sixty-four (66.7%) patients were on a medication listed as potentially inappropriate for use in older adults. The most common potentially inappropriate medication was a proton-pump inhibitor (38.5%), followed by aspirin (24%), tramadol (15.6%), a benzodiazepine (13.5%) or an opioid (8.3%). Eighty-one medications were recommended for deprescribing and 27 medications were discontinued (33.3%). There were 24 recommended dose adjustments and 11 medications were dose adjusted (45.8%). Thirty-four medications were suggested as an addition to the current patient regimen, 2 medications were added (5.9%).

Conclusion
Pharmacist comprehensive medication review is a necessary component of the HBPC healthcare continuum. Additional research is needed to examine whether aligning pharmacists to deliver support to HBPC improves clinical outcomes, reduces healthcare expenditures and improves the patient’s experience.
Od Redakcji
Authors: Churski Paweł 
Published: May 2021

Zapraszamy Państwa do działu Nowości Wydawniczych, w którym prezentujemy najnowsze prace autorstwa pracowników naszego wydziału, których tematyka bezpośrednio wiąże się z problematyką rozwoju regionalnego i polityki regionalnej. W bieżącym numerze przedstawiamy Państwu rozdział autorstwa dr Emilii Bogackiej pt. „Safety of urban park users. The case of Poznań, Poland”, który został opublikowany w monografii „Crime and Fear in Public Places” (red. V. Ceccato, M.K. Nalla) przygotowanej przez Wydawnictwo Routledge.
Transformações institucionais e mudanças climáticas: Pernambuco (Brasil) e em Quebec (Canadá) em uma perspectiva de análise comparativa
Authors: Theodoro Hildelano Delanusse , Ramos Paulo , Tremblay Simon 
Published: May 2021

Considerada como uma temática crescente devido aos inúmeros eventos administrativos e climáticos desenvolvidos, a gestão ambiental requerer um entendimento sobre seus modelos e práticas de atuação. De forma a identificar as particularidades presentes nas questões do meio ambiente em termos de suas transformações institucionais e suas relações com as mudanças climáticas e os recursos hídricos, o artigo discute algumas instituições presentes na província do Quebec, Canadá, e em Pernambuco, Brasil, responsáveis por esses temas. O objetivo foi de identificar as transformações institucionais nos níveis político e institucional que podem possibilitar o cumprimento dos objetivos de reduzir os impactos ambientais, tendo como princípios a democracia, a justiça social e a liberdade, a partir da análise comparativa destes aspectos no estado brasileiro de Pernambuco e a província canadense de Quebec. A pesquisa documental institucional permitiu verificar que existem limites financeiros e de planejamento para que as organizações quebequenses e pernambucanas possam atuar de forma mais efetiva. Da mesma forma, as organizações só podem ser realmente entendidas a partir de sua formação histórica, legal, política e social. Esses elementos são fundamentais para que ambientes de interação entre o conjunto institucional e as necessidades presentes em cada estado e região possam ser levados em consideração de fato, na direção da criação ou consolidação de processos de gestão compartilhada dos recursos ambientais.
Ghrelin (GHRL) Gene Polymorphism and its Association with Growth and Body Size Parameters in Three Nigerian Chicken Breeds
Authors: SANDA Adeyinka , BEMJI Martha , WHETO Mathew , OSO Abimbola , SANDA Mofoyeke , OLOWOFESO Olajide 
Published: May 2021

This study was conducted to identify ghrelin (GHRL) gene polymorphism within exons 2 and 3 in three chicken breeds and to determine its association with growth and linear body measurements. Three hundred one-day-old chicks comprising 100 each of three chicken breeds (FUNAAB Alpha, Noiler and Shika Brown) were used for the research and were raised for eighteen weeks. Fifty birds per breed were sampled for blood collection and Genomic DNA was extracted using Zymo miniprep kit. DNA was amplified and PCR products digested with Eco72I restriction enzyme. Growth data were analysed using Generalized Linear Model of SAS. Noiler had the highest (P <0.05) growth traits from 10 to 18 weeks among studied breeds. GHRL gene polymorphism had no significant (P >0.05) effect on growth traits. However, interaction between GHRL gene polymorphism and chicken breeds revealed that Noiler chickens AA and AB had the best (P <0.05) productive performance from 2 to 18 weeks.
His and hers: visions and narratives in a Brazilian unit of the Unified Health System (SUS)
Authors: Jurberg Claudia , Sousa Camila Pereira Belisário de , Russomano Fábio Bastos 
Published: May 2021

This article tries to understand the intersections and differences of narratives among health professionals, users of a highly complex institution within the Unified Health System (SUS) and mothers of children with complex health conditions; also reflects on actions that can contribute to a better communication among these two actors and the formulation of guiding policies for this dialogical exchange in a more effective and efficient way. Focus groups and semi-structured interviews were carried out, totaling 36 participants, including doctors, nurses, social workers, managers, cleaning professionals, front desks and users/mothers of children under treatment at this institution in Rio de Janeiro, during a six-month period. The results were treated from a qualitative-quantitative perspective using the MAXQDA® software, which supported the identification of synergies and antagonisms among the collected narratives, pointing to three main categories of narratives: communication flow between actors; the perception about the institution, including care aspects; and feelings about health, illness and death. As perspectives, we believe the results can be inspiring when reflecting on Social Determinants in Health and SUS.