bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengembangan Lembar Kerja Siswa Fisika Berbasis Scientific pada Materi Elastisitas dan Hukum Hooke
Authors: Sari Mayang , Amin Ahmad , Arini Wahyu 
Published: June 2021

Penelitian ini bertujuan untuk mengembangakan Lembar Kerja Siswa (LKS) Fisika Berbasis Scientific pada pokok bahasan Elastisitas dan Hukum Hooke yang valid, dan praktis. Masalah dalam penelitian ini adalah 1) Bagaimana mendesain dan mengembangkan Lembar Kerja Siswa Fisika berbasis scientific pada materi Elastisitas dan Hukum Hooke Kelas XI SMA Negeri 4 (Model) Lubuklinggau?, 2) Bagaimana kualitas LKS untuk pembelajaran fisika jika ditinjau dari segi kevalidan, dan kepraktisan?, Subjek dalam penelitian ini adalah kelas XI IPA 5 yang terdiri dari 6 siswa yang diambil dengan teknik purposive sampling. Pengembangan penelitian menggunakan model ADDIE yang terdiri dari 1) Analisis Kebutuhan (Analysis), 2) perancangan (design), 3) pengembangan (develop), 4) Implementasi (Implement), 5) Evaluasi (Evaluation). Pengumpulan data dilakukan dengan teknik angket respon siswa. Dan validasi terdiri dari 3 validasi ahli, validasi materi dengan penilaian 44 dalam kategori sangat baik, validasi bahasa dengan penilaian 18 dalam kategori baik, dan validasi media dengan penilaian 29 dalam kategori baik. Validasi yang dilakukan mendapatkan hasil dengan penilaian 91 dalam kategori baik. Respon siswa terhadap lembar kerja siswa fisika berbasis Scientific dengan penilaian 34,16 dalam kategori sangat baik sedangkan hasil uji kompetensi siswa dengan 6 orang sampel 1 orang tidak tuntas 5 orang yang mencapai KKM. Sehingga dapat dikatakan bahwa Lembar Kerja Siswa fisika berbasis Scientific yang dikembangkan telah Valid, dan praktis.
Forum
Authors: Hughes Geoffrey , Ben-Yehoyada Naor , Scheele Judith , Dua Jatin 
Published: June 2021

Follow the relationship: A note on Jatin Dua’s Captured at Sea: Piracy and Protection in the Western Indian Ocean Protection recaptured: Reflections on Jatin Dua’s Captured at Sea: Piracy and Protection in the Western Indian OceanProtection’s possibility: On histories and geographies of concepts
Atti di fiducia: è utile il concetto di perdono?
Authors: Smith Henry F. 
Published: June 2021

- Using detailed clinical vignettes, the author argues that, despite the current idealization of the concept of forgiveness, the term has no place in psychoanalytic work, and there are some hazards to giving it one. Clinically, the concept of forgiveness is seductive, implying that there should be a common outcome to a variety of injuries, stemming from different situations and calling for different solutions. Every instance of what we call forgiveness can be seen to serve a different defensive function. While the conscious experience of what is called forgiveness is sometimes confused with the unconscious process of reparation, the two can only be described at different levels of psychic life. Despite the fact that in "the unconscious" there is not such a thing as forgiveness; the term has an adhesive quality in our thinking that also blunts the analyst's appreciation of the aggressive components in the work. In a final vignette, the author illustrates an analytic outcome that has the appearance of forgiveness, but is best understood as the complex result of the everyday work of analysis.Parole chiave: Accettazione, aggressività, compromesso, controtransfert, difesa, perdono, riconciliazione, riparazione, risentimentoKey words: Acceptance, aggression, compromise, countertransference, defense, forgiveness, reconciliation, reparation, resentment
Permasalahan Tuntutan Harta Sepencarian Dalam Pembahagian Harta Pusaka
Authors: Ahmad Mohamad Ali Roshidi 
Published: June 2021

Islamic Family Law of all states in Malaysia has recognized jointly acquired property claims. Jointly acquired property can only be claimed by the couple, whether husband or wife. Jointly acquired property can be claimed in three circumstances, namely by reason of divorce, polygamy or death. Although there are legal provisions, there is still a lot of confusion about the claim process after death. Especially from the aspect of the type of property that can be claimed as a jointly acquired property, the method of proving the level of contribution by a person to the acquisition of property, who is eligible to make a claim, the rate of share of property that can be claimed, the method of division of property, claim procedure and so on. This paper will only discuss the issues and problems encountered in the process of claiming jointly acquired property by a spouse before the claim of division of estate is made.
Asbtrak
Undang-undang Keluarga Islam semua negeri di Malaysia telah mengiktiraf tuntutan harta sepencarian. Harta sepencarian hanya boleh dituntut oleh pasangan sahaja, sama ada suami ataupun isteri. Harta sepencarian boleh dituntut dalam tiga keadaan, iaitu dengan sebab berlakunya perceraian, poligami atau kematian. Walaupun peruntukan undang-undang telah ada, tetapi masih terdapat banyak kekeliruan terhadap proses tuntutan selepas kematian. Terutama dari aspek jenis harta yang boleh dituntut sebagai harta sepencarian, kaedah pembuktian tahap sumbangan oleh seseorang terhadap pemerolehan harta, siapa yang layak membuat tuntutan, kadar bahagian harta yang boleh dituntut, cara pembahagian harta, prosedur tuntutan dan sebagainya. Kertaskerja ini hanya akan membincangkan mengenai isu-isu dan masalah-masalah yang dihadapi dalam proses tuntutan harta sepencarian oleh seorang pasangan sebelum tuntutan pembahagian harta pusaka dibuat
STRATEGI KREATIF PERIKLANAN “PINED WEARHOUSE PERIGEE” MELALUI MEDIA SOSIAL INSTAGRAM
Authors: Dianputri Pita , Rosmiati, S.Pd., M.Hum Ana 
Published: June 2021

Perkembangan dunia fashion (gaya atau mode berpakaian) adalah perkembangan yang terjadi paling pesat. Berbagai pihak usaha dalam bidang serupa berlomba-lomba dalam menciptakan sebuah strategi kreatif periklanannya. Poster merupakan salah satu media yang dipilih untuk kegiatan promosi serta media sosial instagram dipilih sebagai pelengkap untuk mendukung keberhasilan kegiatan promosinya. Penelitian ini bertujuan untuk mendiskripsikan tentang bagaimana strategi kreatif periklanan toko pakaian Pined Wearhouse Perigee yang bersegmen concept store (toko yang berkonsep) dan memililih media sosial Instagram sebagai media beriklannya. Metode penelitian yang dipilih yaitu kualitatif deskriptif dengan mengumpulkan data melalui proses dokumentasi, studi kepustakaan, observasi dan wawancara. Analisis data dilakukan dengan menanganalisis beberapa tahapan strategi kreatif antara lain yaitu permasalahan yang ada, survey khalayak untuk target market yang dituju, posisi brand yang ingin dihadirikan dalam benak konsumen, tujuan komunikasi yang ingin dicapai, usulan berupa ide yang digunakan untuk menenentukan karakter beriklannya, media poster yang dipilih dan media sosial instagram digunakan sebagai media untuk meluncurkan iklannya, serta arah kreatif sebagai sebuah gaya penyampaian pesan yang unik, menganalisis konsep desain dengan mengurai elemen-elemen desain dalam posternya, antara lain logo, ilustrasi, layout, dan warna serta pemanfaatan media sosial Instagram yang dipilih sebagai media promosinya.
Estimation of Carbon Stock in the Sylhet Basin Soils of Bangladesh
Authors: Uddin MJ , Rahman Arafat , Ali AHM Zulfiquar , Rahman Md Khalilur 
Published: June 2021

Wetland basin soils are the major store houses of organic carbon where there is a scope to use this carbon in mitigating the climate change. A study was conducted in these basin soils at 100 cm depth regarding their carbon stock. The study showed that total soil organic carbon (SOC) stock in the Sylhet basin soils of Bangladesh is 0.094 Pg where the SOC stock was 0.044 Pg in medium low land sites and it was about 0.050 Pg in lowland sites. There was no previous study on SOC stock in the Sylhet basin soils of Bangladesh. These may act as benchmark SOC stock datasets for the future agricultural planning. The soil organic carbon stock is higher in the lowland than medium lowland sites. The contents of SOC are low is compared to its threshold levels. Moreover, it is apprehended that basin soils may lose their carbon due to the decrease of inundation level by climate change, and other eco-environmental changes. So, it is very much urgent to take steps in preserving the organic carbon of lowland basin soils.
Asiat. Soc. Bangladesh, Sci. 46(1): 49-60, June 2020
Introducción a la tecnología de membranas para la purificación de biogas y algunos desarrollos recientes
Authors: Arbelaez-Perez Oscar Felipe , Cardona-Gonzalez Cristian , Molina-Cardona Diego Andres , González-Chevejoni Roger Junior 
Published: June 2021

La remoción de CO2 en mezclas de CO2/CH4 para aumentar el contenido de energía en gas natural o biogás y prevenir problemas de corrosión, ha impulsado el desarrollo del proceso de separación de CO2 utilizando membranas. Las características más relevantes que ofrece la tecnología basada en membranas incluyen la alta eficiencia energética, el costo reducido y el rendimiento altamente flexible. Esta revisión proporciona una descripción de los trabajos reportados desde 2010 hasta 2020 sobre los diferentes tipos de membranas disponibles: poliméricas, inorgánicas y de matriz mixta para el proceso de separación de CO2/CH4; se reportan las condiciones experimentales y los determinantes primarios del rendimiento y la eficiencia de la separación (permeabilidad de CO2 y selectividad CO2/CH4). Este trabajo ofrece una nueva perspectiva de cada membrana para facilitar una mejor apreciación de su papel en la mejora del rendimiento general del proceso
The remotion of CO2 from CO2/CH4 mixes to increasing energy content in natural gas or biogas and to prevent corrosion problems, has driven the development of CO2 separation process through membranes. The attractive features offered by this technology include high energy efficiency, reduced cost and highly flexible performance. This review provides an overview of the reported paper from 2010 to 2020 different types of membranes available: polymeric, inorganic and mixed matrix for CO2/CH4 separation process, experimental conditions and primary determinants of separation performance and efficiency (permeability of CO2 and CO2/CH4 selectivity). This work would open up a new perspective of each membrane to facilitate a better appreciation of their role in the improvement of overall process performance.
KAJIAN FAKTOR KENDALA DOKTER TIDAK MENGGUNAKAN APLIKASI WIFI TB DI KOTA SEMARANG
Authors: Kurniadi Arif , Widianawati Evina , Ernawati Dyah 
Published: June 2021

Tuberkulosis (TB) merupakan salah satu dari sepuluh penyakit penyebab kematian di dunia dengan angka kejadian 10,0 juta (kisaran, 9,0–11,1 juta) penderita TB pada tahun 2018.1 Dalam pengelolaannya, kasus TB yang ditemukan harus dicatat dan dilaporkan oleh setiap fasilitas pelayanan kesehatan sesuai format yang ditentukan. Upaya pemberdayaan secara aktif untuk pelaporan kasus dilakukan dokter dengan bantuan teknologi menggunakan aplikasi WifiTB. Penelitian ini bertujuan untuk menganalisis faktor-faktor kendala yang mempengaruhi minat dokter tidak menggunakan aplikasi WifiTB di wilayah kerja Dinas Kesehatan Kota Semarang. Data diperoleh lewat kuesioner dengan skala linkert yang diisi oleh dokter sebagai pemakai aplikasi sebanyak 129 kuesioner dengan mengolah 77 kuesionar dokter yang belum menggunakan aplikasi. Dengan menggunakan teknik analisis faktor, hasil penelitian menunjukkan bahwa persepsi negatif 86,2%, smartphone 79,5% dan kesiapan 78,5% paling mempengaruhi minat dokter dalam menggunakan aplikasi WifiTB. Sehingga dengan demikian upaya pendekatan persuasif perlu ditingkatkan guna menambah keyakinan dan kesiapan para dokter dalam menggunaan aplikasi WifiTB.
Subkorakoid sıkışmada, korakoid morfolojisinin, korakohumeral mesafenin, korakoglenoid açının ve korakohumeral açının MRG ile değerlendirilmesi
Authors: KAPLANOĞLU Veysel , KAPLANOĞLU Hatice 
Published: June 2021

Amaç: Bu çalışmanın amacı, korakoid morfolojisi, korakohumeral mesafe,korakoglenoid açı ve korakohumeral açı değişkenlerinin subkorakoid sıkışma gelişimi üzerine etkileri manyetik rezonans (MRG) ile değerlendirilmektir. Gereç ve Yöntem: Retrospektif çalışmaya omuz MRG çekilen toplam 255 hasta (ort. yaş 51.25±15.77 olan 115 erkek ve ort.yaş 53.13±14.75 olan 140 kadın) alındı. MRG incelemeleri standart pozisyonda yapıldı. Korakoid morfolojisi ve subskapularis tendonu değerlendirildi. Tüm olgularda korakohumeral mesafe, korakoglenoid açı ve korakohumeral açı ölçüldü. Gruplar arasındaki farkı değerlendirmek için tek yönlü ANOVA kullanıldı. İkili karşılaştırmalar için, Tukey post hoc analizi yapıldı. Değişkenler arasında Pearson korelasyon analizi yapıldı. Bulgular: Subskapularis tendonu yırtık olan grupta en sık Tip C korakoid görüldü. Korakohumeral mesafe, korakoglenoid açı ve korakohumeral açı değerleri için korakoid tipleri arasında istatistiksel olarak anlamlı bir fark saptanmadı (p&gt; 0.05). Subskapularis tendon yırtığı olan hastalarda korakoglenoid açı değerlerinde ve korakohumeral mesafede istatistiksel olarak anlamlı bir azalma vardı (p= 0.000). Korakohumeral açı değeri için tendonu normal olanlar, tendinozis olanlar ve yırtık olan grupların ortalamaları arasında fark yoktu (p&gt;0.05). Korakohumeral mesafe ile korakoglenoid açı arasında pozitif yönlü korelasyon bulundu (r=0.239, p&lt;0.001). Korakoglenoid açı ile korakohumeral açı arasında negatif yönlü korelasyon bulundu (r=-0.320 , p&lt;0.001). Sonuç: Subskapularis tendon patolojilerinde korakohumeral mesafe ve korakoglenoid açıda azalma gözlendi. Tip C korakoid subkorakoid sıkışmada etkili ve önemli bir faktördür.
Development and Validation of a Robust Ferroptosis-Related Prognostic Signature in Lung Adenocarcinoma
Authors: Zhang Anran , Yang Jinpo , Ma Chao , Li Feng , Luo Huan 
Published: June 2021

BackgroundLung adenocarcinoma (LUAD) is the most common subtype of non-small cell lung cancer. Ferroptosis is a newly recognized process of cell death, which is different from other forms of cell death in morphology, biochemistry, and genetics, and has played a vital role in cancer biology. This study aimed to identify a ferroptosis-related gene signature associated with LUAD prognosis.MethodsDataset TCGA-LUAD which came from the TCGA portal was taken as the training cohort. GSE72094 and GSE68465 from the GEO database were treated as validation cohorts. Two hundred fifty-nine ferroptosis-related genes were retrieved from the FerrDb database. In the training cohort, Kaplan–Meier and univariate Cox analyses were conducted for preliminary screening of ferroptosis-related genes with potential prognostic capacity. These genes then entered into the LASSO Cox regression model, constructing a gene signature. The latter was then evaluated in the training and validation cohortsviaKaplan–Meier, Cox, and ROC analyses. In addition, the correlations between risk score and autophagy were examined by Pearson correlation coefficient. The analyses of GSEA and immune infiltrating were performed for better studying the function annotation of the gene signature and the character of each kind of immune cells played in the tumor microenvironment.ResultsA 15-gene signature was found from the training cohort and validated by Kaplan–Meier and Cox regression analyses, revealing its independent prognosis value in LUAD. Moreover, the ROC analysis was conducted, confirming a strong predictive ability that this signature owned for LUAD prognosis. One hundred fifty-one of 222 (68.01%) autophagy-related genes were discovered significantly correlated with risk scores. Analyses of GSEA and immune infiltration exhibited in detail the specific pathways that associate with the 15-gene signature and identified the crucial roles of resting mast cells and resting dendritic cells owned in the prognosis of the 15-gene signature.ConclusionIn this present study, a novel ferroptosis-related 15-gene signature (RELA, ACSL3, YWHAE, EIF2S1, CISD1, DDIT4, RRM2, PANX1, TLR4, ARNTL, LPIN1, HERPUD1, NCOA4, PEBP1, and GLS2) was built. It could accurately predict the prognosis of LUAD and was related to resting mast cells and resting dendritic cells, which provide potential for the personalized outcome prediction and the development of new therapies in LUAD population.
ZIF-12/Fe-Cu LDH Composite as a High Performance Electrocatalyst for Water Oxidation
Authors: Hameed Arslan , Batool Mariam , Iqbal Waheed , Abbas Saghir , Imran Muhammad , Khan Inayat Ali , Nadeem Muhammad Arif 
Published: June 2021

Layered double hydroxides (LDH) are being used as electrocatalysts for oxygen evolution reactions (OERs). However, low current densities limit their practical applications. Herein, we report a facile and economic synthesis of an iron-copper based LDH integrated with a cobalt-based metal-organic framework (ZIF-12) to form LDH-ZIF-12 composite (1) through a co-precipitation method. The as-synthesized composite1requires a low overpotential of 337 mV to achieve a catalytic current density of 10 mA cm−2with a Tafel slope of 89 mV dec−1. Tafel analysis further demonstrates that1exhibits a slope of 89 mV dec−1which is much lower than the slope of 284 mV dec−1for LDH and 172 mV dec−1for ZIF-12. The slope value of1is also lower than previously reported electrocatalysts, including Ni-Co LDH (113 mV dec−1) and Zn-Co LDH nanosheets (101 mV dec−1), under similar conditions. Controlled potential electrolysis and stability test experiments show the potential application of1as a heterogeneous electrocatalyst for water oxidation.
Plasmodium vivax Gametocytes Adherence to Bone Marrow Endothelial Cells
Authors: Salazar Alvarez Luis Carlos , Vera Lizcano Omaira , da Silva Barros Dayanne Kamylla Alves , Baia-da-Silva Djane Clarys , Monteiro Wuelton Marcelo , Pimenta Paulo Filemon Paolluci , de Lacerda Marcus Vinicius Guimarães , Costa Fabio Trindade Maranhão , Lopes Stefanie Costa Pinto 
Published: June 2021

In a Plasmodium vivax infection, it was shown a proportionally increased on gametocyte distribution within the bone marrow aspirant, suggesting a role of this organ as a reservoir for this parasite stage. Here, we evaluated the ex vivo cytoadhesive capacity of P. vivax gametocytes to bone marrow endothelial cells (HBMEC) and investigated the involvement of some receptors in the cytoadhesion process by using transfected CHO cells (CHO-ICAM1, CHO-CD36 and CHO-VCAM), wild type (CHO-K1) or deficient in heparan and chondroitin sulfate (CHO-745). Ex-vivo cytoadhesion assays were performed using a total of 44 P. vivax isolates enriched in gametocyte stages by Percoll gradient in the different cell lines. The majority of isolates (88.9%) were able to adhere to HBMEC monolayer. ICAM1 seemed to be the sole receptor significantly involved. CD-36 was the receptor with higher adhesion rate, despite no significance was noticed when compared to CHO-745. We demonstrated that gametocyte P. vivax adheres ex vivo to bone marrow endothelial cells. Moreover, P. vivax gametocytes display the ability to adhere to all CHO cells investigated, especially to CHO-ICAM1. These findings bring insights to the comprehension of the role of the bone marrow as a P. vivax reservoir and the potential impact on parasite transmission to the vector.
Next-Generation Sequencing Analysis Reveals Frequent Familial Origin and Oligogenism in Congenital Hypothyroidism With Dyshormonogenesis
Authors: Oliver-Petit Isabelle , Edouard Thomas , Jacques Virginie , Bournez Marie , Cartault Audrey , Grunenwald Solange , Savagner Frédérique 
Published: June 2021

ContextCongenital hypothyroidism (CH) is related to dyshormonogenesis in 15% to 40% of the world population and associated with homozygous or heterozygous variants in the main genes of the hormone synthesis pathway. Emerging diagnostic tools, such as next-generation sequencing (NGS), have been used to efficiently explore panels of genes and identify complex mechanisms of pathogenesis.ObjectiveWe explored 19 candidate genes known to be causative for permanent or transient CH to evaluate the role of complex gene variations in CH phenotype.Patients, Design and SettingUsing the NGS approach, we studied 65 newborns with thyroid dyshormonogenesis (TDH). New variants were assessed in silico for pathogenicity.ResultsAmong the 65 infants, 56.9% presented a variant in one or more genes of the thyroid hormone synthesis axis. We identified homozygous or compound heterozygous variants in the TG, DUOX2, TPO, or SLC5A5 genes in 10 infants and heterozygous variants in DUOX2, TG, TPO, and TSHR in 19 others. In seven cases, a heterozygous variant in the TG gene was the unique anomaly detected, but related to disturbed hormonal balance. Oligogenic variants were found in eight infants associated with severe CH and goiter in five of them.ConclusionThe systematic exploration of genes involved in thyroid hormone synthesis by NGS in TDH showed high diagnostic relevance. Oligogenic inheritance could be related to phenotypic heterogeneity and a high frequency of goiter.
A Novel Homozygous In-Frame Deletion in Complement Factor 3 Underlies Early-Onset Autosomal Recessive Atypical Hemolytic Uremic Syndrome - Case Report
Authors: Pollack Shirley , Eisenstein Israel , Mory Adi , Paperna Tamar , Ofir Ayala , Baris-Feldman Hagit , Weiss Karin , Veszeli Nóra , Csuka Dorottya , Shemer Revital , Glaser Fabian , Prohászka Zoltán , Magen Daniella 
Published: June 2021

Background and ObjectivesAtypical hemolytic uremic syndrome (aHUS) is mostly attributed to dysregulation of the alternative complement pathway (ACP) secondary to disease-causing variants in complement components or regulatory proteins. Hereditary aHUS due to C3 disruption is rare, usually caused by heterozygous activating mutations in the C3 gene, and transmitted as autosomal dominant traits. We studied the molecular basis of early-onset aHUS, associated with an unusual finding of a novel homozygous activating deletion in C3.Design, Setting, Participants, &amp; MeasurementsA male neonate with eculizumab-responsive fulminant aHUS and C3 hypocomplementemia, and six of his healthy close relatives were investigated. Genetic analysis on genomic DNA was performed by exome sequencing of the patient, followed by targeted Sanger sequencing for variant detection in his close relatives. Complement components analysis using specific immunoassays was performed on frozen plasma samples from the patient and mother.ResultsExome sequencing revealed a novel homozygous variant in exon 26 of C3 (c.3322_3333del, p.Ile1108_Lys1111del), within the highly conserved thioester-containing domain (TED), fully segregating with the familial disease phenotype, as compatible with autosomal recessive inheritance. Complement profiling of the patient showed decreased C3 and FB levels, with elevated levels of the terminal membrane attack complex, while his healthy heterozygous mother showed intermediate levels of C3 consumption.ConclusionsOur findings represent the first description of aHUS secondary to a novel homozygous deletion in C3 with ensuing unbalanced C3 over-activation, highlighting a critical role for the disrupted C3-TED domain in the disease mechanism.