bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating effect of polymer concentrations on separation performance of hydrocyclone by sensitivity analysis
Authors: Liu Yang , Bu Fanxi , Chen Shuangqing , Jiang Minghu 
Published: March 2021

AbstractPolymer flooding technology is widely used to enhance the oil recovery, but it increases the viscosity of the produced liquid, making the subsequent water treatment more challenging. Application of polymers impacts separation performance of hydrocyclone, which is an important equipment of produced liquid preseparation and sewage treatment in oil fields. In this work, the effect of polymer solution concentrations on the separation performance of hydrocyclone was studied by using sensitivity analysis. The sensitivity was calculated by numerical simulation, and the influence of polymer concentration on velocity field, pressure field, oil volume fraction, and separation efficiency of hydrocyclone was evaluated. The prototype was processed according to the similarity principle of fluid mechanics, and the relevant laboratory tests were carried out to verify the accuracy of simulation results. Within the tested range (100‐1000 mg/L), the increase of polymer solution concentrations caused adverse impacts on the velocity field, pressure field, and oil volume fraction of the hydrocyclone. When the concentrations of polymer solution reached 800 mg/L, the separation efficiency was reduced to less than 60%. The sensitivity sequence obtained by calculation is as follows: underflow outlet pressure drop > overflow outlet pressure drop > axial velocity > radial velocity > tangential velocity > pressure drop ratio. The change of pressure drop at underflow and overflow outlets was the primary cause for poor separation performance of hydrocyclone. The work can be used to guide the design and application of hydrocyclone for efficient treatment of polymer‐containing treatment liquid.
Electrodeposition of Ni on MWNTs as a promising catalyst for CO2RR
Authors: Huo Siming , Lu Jessie , Wang Xianqin 
Published: March 2021

AbstractNovel methods for the preparation of metal‐supported materials are desired for better catalytic performance and selectivity. In this article, Ni supported on multiwall nanotubes (Ni/MWNTs) is synthesized with electrodeposition method for electrocatalytic CO2 reduction reaction (CO2RR). The sample drying time after electrodeposition is found critical to oxidize Ni for better activity, and higher Ni oxidation state is required for CO2RR. The loading effect study proves that higher current density is achieved from small Ni clusters than that from large nano particles. This work provides a pioneer approach to synthesize small Ni clusters using electrodeposition method for electrocatalytic CO2 conversion.
A comparative study of essential oil constituents, total phenolics and antioxidant capacity of the different organs of four species of the genus bunium
Authors: Adelifar Najmeh , Rezanejad Farkhondeh 
Published: March 2021

AbstractBunium persicum is one of the fragrant herbaceous plants that has many nutritional and medicinal applications. Information about other species of Bunium is scarce. Essential oils, polyphenolics and antioxidant activity were analysed in four species of Bunium. The highest levels of total flavonoids were observed in leaves and fruits of B wolffii while the other polyphenolics did not show significant differences between the species and organs. Gas chromatography‐mass spectrometry (GC/MS) analysis revealed 16, 14, 14 and 13 main components respectively accounting for 97.52% of the entire essential oils of B cylindricum, 91.12% of B paucifolium, 97.14% B persicum and 96.41% of B wolffii. The monoterpenes content was 57.9, 22, 97.14 and 63.83% in B cylindricum, B paucifolium, B persicum and B wolffii respectively whereas sesquiterpenes levels were respectively 1.29, 27.45, 0.0 and 2.98%. The nonterpens constituted 38.33, 41.67, 0.0 and 29.6% in these four species respectively. The highest amount of monoterpenes (97.14%) was observed in B persicum, while the maximum of sesquiterpenes (27.45%) and nonterpenes (41.67%) obtained in B paucifolium. The main constituents were γ‐terpinene, myristicin, cuminaldehyde, apiole, α‐pinene, β‐pinene, β‐selinene, Z‐ β‐ocimene and γ‐terpinene‐7‐al. Cuminaldehyde with the pleasant odour was only revealed in B persicum. All organs of different species except corms showed high antioxidant activity using ABTS and DPPH assay. Thus, similar to B persicum, the other studied species are a rich source of antioxidant compounds and can be used as functional food ingredients and a potential source of natural antioxidants with valuable health benefits.
Targeted locus amplification to detect molecular markers in mantle cell and follicular lymphoma
Authors: Genuardi Elisa , Klous Petra , Mantoan Barbara , Drandi Daniela , Ferrante Martina , Cavallo Federica , Alessandria Beatrice , Dogliotti Irene , Grimaldi Daniele , Ragaini Simone , Clerico Michele , Lo Schirico Mariella , Saraci Elona , Yilmaz Mehmet , Zaccaria Gian Maria , Cortelazzo Sergio , Vitolo Umberto , Luminari Stefano , Federico Massimo , Boccadoro Mario , van Min Max , Splinter Erik , Ladetto Marco , Ferrero Simone 
Published: March 2021

AbstractMinimal residual disease (MRD) monitoring by PCR methods is a strong and standardized predictor of clinical outcome in mantle cell lymphoma (MCL) and follicular lymphoma (FL). However, about 20% of MCL and 40% of FL patients lack a reliable molecular marker, being thus not eligible for MRD studies. Recently, targeted locus amplification (TLA), a next‐generation sequencing (NGS) method based on the physical proximity of DNA sequences for target selection, identified novel gene rearrangements in leukemia. The aim of this study was to test TLA in MCL and FL diagnostic samples lacking a classical, PCR‐detectable, t(11; 14) MTC (BCL1/IGH), or t(14; 18) major breakpoint region and minor cluster region (BCL2/IGH) rearrangements. Overall, TLA was performed on 20 MCL bone marrow (BM) or peripheral blood (PB) primary samples and on 20 FL BM, identifying a novel BCL1 or BCL2/IGH breakpoint in 16 MCL and 8 FL patients (80% and 40%, respectively). These new breakpoints (named BCL1‐TLA and BCL2‐TLA) were validated by ASO primers design and compared as MRD markers to classical IGH rearrangements in eight MCL: overall, MRD results by BCL1‐TLA were superimposable (R Pearson = 0.76) to the standardized IGH‐based approach. Moreover, MRD by BCL2‐TLA reached good sensitivity levels also in FL and was predictive of a primary refractory case. In conclusion, this study offers the proof of principle that TLA is a promising and reliable NGS‐based technology for the identification of novel molecular markers, suitable for further MRD analysis in previously not traceable MCL and FL patients.
A qualitative study of patient perspectives of diabetes and diabetic retinopathy services in Vanuatu
Authors: ‘Ofanoa Malakai , Aitip Basil , Ram Komal , Dalmia Prarthana , Pal Moneeta , Nosa Vili , Goodyear‐Smith Felicity 
Published: March 2021

AbstractIssue addressedDiabetes mellitus is an increasing global health problem, particularly in Vanuatu, where it poses a major health burden. There is paucity of information on how patients in Vanuatu perceive diabetes, diabetic retinopathy, access to services and management, health promotion and intervention services to alleviate the issues. This study aimed to explore the perceptions of diabetic patients in Vanuatu on these issues, to help inform the design of health promotion materials and community activities to empower people to self‐manage and shape diabetic services that are integrated and people‐centred.MethodsQualitative Talanga and Kakala Pacific research methodologies were applied. Participants were diabetic patients from both urban locations and rural villages in Vanuatu. Data were collected from four (two male, two female) focus group interviews and thematically analysed.ResultsThere were 26 participants. System failures became apparent, including the inability of the health care services to meet the complex needs of patients with diabetes. The protective factors to reduce the risk and increasing incidence of diabetes and diabetic retinopathy included comprehensive village‐based health promotion and community development programmes at the primary prevention level.ConclusionThis study described patients' experiences of their diabetic care and identified key barriers and facilitators of service delivery pathways.So what?Vanuatu needs to expand nationwide health promotion and education programmes on nutrition and exercise, food insecurity and access through trade agreements and provide well‐trained nursing and medical specialists for early diagnosis and adequate management of diabetes that all people can access and afford.
The value of spot urinary creatinine as a marker of muscle wasting in patients with new‐onset or worsening heart failure
Authors: Pandhi Paloma , Streng Koen W. , Anker Stefan D. , Cleland John G. , Damman Kevin , Dickstein Kenneth , Pellicori Pierpaolo , Lang Chim C. , Ng Leong , Samani Nilesh J. , Zannad Faiez , Metra Marco , Rossignol Patrick , Filippatos Gerasimos , van Veldhuisen Dirk J. , Voors Adriaan A. , ter Maaten Jozine M. 
Published: March 2021

AbstractBackgroundMuscle wasting and unintentional weight loss (cachexia) have been associated with worse outcomes in heart failure (HF), but timely identification of these adverse phenomena is difficult. Spot urinary creatinine may be an easily accessible marker to assess muscle loss and cachexia. This study investigated the association of urinary creatinine with body composition changes and outcomes in patients with new‐onset or worsening HF (WHF).MethodsIn BIOSTAT‐CHF, baseline spot urinary creatinine measurements were available in 2315 patients with new‐onset or WHF in an international cohort (index cohort) and a validation cohort of 1431 similar patients from Scotland.ResultsMedian spot urinary creatinine concentrations were 5.2 [2.7–9.6] mmol/L in the index cohort. Median age was 69 ± 12 years and 73% were men. Lower spot urinary creatinine was associated with older age, lower height and weight, worse renal function, more severe HF, and a higher risk of >5% weight loss from baseline to 9 months (odds ratio = 1.23, 95% CI = 1.09–1.39 per log decrease; P = 0.001). Spot urinary creatinine was associated with Evans criteria of cachexia (OR = 1.26 per log decrease, 95% CI = 1.04–1.49; P = 0.016) and clustered with markers of heart failure severity in hierarchical cluster analyses. Lower urinary creatinine was associated with poorer exercise capacity and quality of life (both P < 0.001) and predicted a higher rate for all‐cause mortality [hazard ratio (HR) = 1.27, 95% CI = 1.17–1.38 per log decrease; P < 0.001] and the combined endpoints HF hospitalization or all‐cause mortality (HR = 1.23, 95% CI = 1.15–1.31 per log decrease; P < 0.001). Significance was lost after addition of the BIOSTAT risk model. Analyses of the validation cohort yielded similar findings.ConclusionsLower spot urinary creatinine is associated with smaller body dimensions, renal dysfunction, and more severe HF in patients with new‐onset/WHF. Additionally, lower spot urinary creatinine is associated with an increased risk of weight loss and a poorer exercise capacity/quality of life. Urinary creatinine could therefore be a novel, easily obtainable marker to assess (risk of) muscle wasting in HF patients.
The impact of tropical storms on tax revenue
Authors: Mohan Preeya , Strobl Eric 
Published: March 2021

AbstractWe investigate the vulnerability of tax revenue and its various sources to hurricane damages. To this end, we construct a monthly panel of hurricane losses, tax revenue, and its components, tax rates, and gross domestic product (GDP) for eight Eastern Caribbean countries over 14 years. Panel vector autoregressions (VAR) show that following a hurricane, any effects are generally short term. The cumulative expected loss in total tax revenue is 5.3%. Revenue derived from international trade and transactions and domestic goods and service are the most negatively affected. Countries with higher value added, as well as international trade and transactions tax rates, appear to be able to buffer the negative impact better, whereas higher property taxes amplify the negative impact of damaging hurricanes on this revenue source.
Translational balancing questioned: Unaltered glycosylation during disulfiram treatment in mannosyl‐oligosaccharide alpha‐1,2‐mannnosidase‐congenital disorders of glycosylation (MAN1B1‐CDG)
Authors: Kemme Lisa , Grüneberg Marianne , Reunert Janine , Rust Stephan , Park Julien , Westermann Cordula , Wada Yoshinao , Schwartz Oliver , Marquardt Thorsten 
Published: March 2021

AbstractMAN1B1‐CDG is a multisystem disorder caused by mutations in MAN1B1, encoding the endoplasmic reticulum mannosyl‐oligosaccharide alpha‐1,2‐mannnosidase. A defect leads to dysfunction within the degradation of misfolded glycoproteins. We present two additional patients with MAN1B1‐CDG and a resulting defect in endoplasmic reticulum‐associated protein degradation. One patient (P2) is carrying the previously undescribed p.E663K mutation. A therapeutic trial in patient 1 (P1) using disulfiram with the rationale to generate an attenuation of translation and thus a balanced, restored ER glycoprotein synthesis failed. No improvement of the transferrin glycosylation profile was seen.
Impact of Wideband Late Gadolinium Enhancement Cardiac Magnetic Resonance Imaging on Device‐Related Artifacts in Different Implantable Cardioverter‐Defibrillator Types
Authors: Singh Amita , Chen Wensu , Patel Hena N. , Alvi Nazia , Kawaji Keigo , Besser Stephanie A. , Tung Roderick , Zou Jiangang , Lang Roberto M. , Mor‐Avi Victor , Patel Amit R. 
Published: March 2021

BackgroundLate gadolinium enhancement (LGE) imaging in patients with implantable cardioverter‐defibrillators (ICD) is limited by device‐related artifacts (DRA). The use of wideband (WB) LGE protocols improves LGE images, but their efficacy with different ICD types is not well known.PurposeTo assess the effects of WB LGE imaging on DRA in different non‐MR conditional ICD subtypes.Study TypeRetrospective.PopulationA total of 113 patients undergoing cardiac magnetic resonance imaging with three ICD subtypes: transvenous (TV‐ICD, N = 48), cardiac‐resynchronization therapy device (CRT‐D, N = 48), and subcutaneous (S‐ICD, N = 17).Field Strength/Sequence5 T scanner, standard LGE, and WB LGE imaging with a phase‐sensitive inversion recovery segmented gradient echo sequence.AssessmentDRA burden was defined as the number of artifact‐positive short‐axis LGE slices as percentage of the total number of short‐axis slices covering the left ventricle from based to apex, and was determined for WB and standard LGE studies for each patient. Additionally, artifact area on each slice was quantified.Statistical TestsShapiro–Wilks, Kruskal–Wallis analysis of variance, Dunn tests with Bonferroni correction, and Mann–Whitney U‐test.ResultsIn patients with TV‐ICD, DRA burden was significantly reduced and nearly eliminated with WB LGE compared to standard LGE imaging (median [interquartile range]: 0 [0–7]% vs. 18 [0–50]%, P < 0.05), but WB imaging had less of an impact on DRA in the CRT‐D (8 [0–23]% vs. 16 [0–45]%, p = 0.12) and S‐ICD (60 [15–71]% vs. 67 [50–92]%, P = 0.09) patients. Residual DRA was significantly greater (P < 0.05) for S‐ICD compared to other device types with WB LGE imaging, despite the generators of all three ICD types having similar proximity to the heart. The area of S‐ICD associated DRA was smaller with WB LGE (P < 0.001) than with standard LGE imaging and the artifacts had different characteristics (dark signal void instead of a bright hyperenhancement artifact).Data ConclusionAlthough WB LGE imaging reduced the burden of DRA caused by S‐ICD, the residual artifact was greater than that observed with TV‐ICD and CRT‐D devices. Further developments are needed to better resolve S‐ICD artifacts.Level of Evidence1Technical Efficacy: Stage5
Shared leadership and relationship conflict in teams: The moderating role of team power base diversity
Authors: Sinha Ruchi , Chiu Chia‐Yen (Chad) , Srinivas Santosh B. 
Published: March 2021

SummaryShared leadership in teams is believed to be beneficial for team effectiveness. Yet recent empirical evidence shows that it may not always bring positive effects. On the one hand, the team leadership literature suggests that shared leadership allows for frequent interactions among members, improving intrateam harmony and reducing conflicts. On the other hand, the team power literature suggests that frequent influence interactions among multiple leaders can form an arena in which members fight over their power turfs, thereby triggering conflict. Drawing on dominance complementarity theory, we suggest that team power base diversity—the variety in power bases among team members from which they derive their informal influence—is an important contingency that moderates the impact of shared leadership on relationship conflict to influence team performance. In a sample of 70 project‐based teams, we find support for the proposition that at high levels of team power base diversity, shared leadership has a positive downstream effect on team performance through reduced team relationship conflict. We discuss the contributions to knowledge about shared leadership and highlight practical implications for temporary teams with no formally designated leaders.
Improving the reporting quality of reliability generalization meta‐analyses: The REGEMA checklist
Authors: Sánchez‐Meca Julio , Marín‐Martínez Fulgencio , López‐López José Antonio , Núñez‐Núñez Rosa Maria , Rubio‐Aparicio María , López‐García Juan José , López‐Pina José Antonio , Blázquez‐Rincón Desirée Mª. , López‐Ibáñez Carmen , López‐Nicolás Rubén 
Published: March 2021

AbstractReliability generalization (RG) is a meta‐analytic approach that aims to characterize how reliability estimates from the same test vary across different applications of the instrument. With this purpose RG meta‐analyses typically focus on a particular test and intend to obtain an overall reliability of test scores and to investigate how the composition and variability of the samples affect reliability. Although several guidelines have been proposed in the meta‐analytic literature to help authors improve the reporting quality of meta‐analyses, none of them were devised for RG meta‐analyses. The purpose of this investigation was to develop REGEMA (REliability GEneralization Meta‐Analysis), a 30‐item checklist (plus a flow chart) adapted to the specific issues that the reporting of an RG meta‐analysis must take into account. Based on previous checklists and guidelines proposed in the meta‐analytic arena, a first version was elaborated by applying the nominal group methodology. The resulting instrument was submitted to a list of independent meta‐analysis experts and, after discussion, the final version of the REGEMA checklist was reached. In a pilot study, four pairs of coders applied REGEMA to a random sample of 40 RG meta‐analyses in Psychology, and results showed satisfactory inter‐coder reliability. REGEMA can be used by: (a) meta‐analysts conducting or reporting an RG meta‐analysis and aiming to improve its reporting quality; (b) consumers of RG meta‐analyses who want to make informed critical appraisals of their reporting quality, and (c) reviewers and editors of journals who are considering submissions where an RG meta‐analysis was reported for potential publication.
Disentangling the Symptom‐Level Nuances in Comorbid Posttraumatic Stress Disorder and Problematic Alcohol Use in Northern Irish Military Veterans: A Network Analysis
Authors: McGlinchey Emily , Ross Jana , Murphy Dominic , Shorter Gillian W. , Armour Cherie 
Published: March 2021

AbstractPosttraumatic stress disorder (PTSD) and alcohol use are highly prevalent among military veteran populations. Several theories have been proposed to account for the comorbidity between PTSD and problematic alcohol use, but research examining the symptom‐level associations between the two is limited. The current study used network analysis to examine the associations between PTSD and problematic alcohol use. Data were collected through a cross‐sectional survey of veterans of the United Kingdom Armed Forces living in Northern Ireland. The sample comprised 511 (91.2% male) veterans with a history of trauma exposure and current alcohol use. A network consisting of PTSD symptoms from the PTSD Checklist for DSM‐5 (PCL‐5) and items from the Alcohol Use Disorders Identification Test (AUDIT) was constructed, and the bridge centrality of all items was estimated to identify items with the highest number of associations and the strongest associations between the two constructs. The PTSD symptom “reckless behavior” (2.43) had the highest bridge centrality values and thus the strongest connections and most connections to the alcohol use items. For the alcohol use items, “not being able to stop drinking” (2.31) and “number of drinks” (1.24) demonstrated the strongest bridge connections to the PTSD items. These results highlight the role of specific PTSD symptoms involved in the interaction between PTSD and problematic alcohol use.
The Impact of Traumatic Stress, Social Support, and Substance Problems on Graduation Among Female Offenders in a Prescription Drug Court Program
Authors: Abarno Cristina N. , De Leon Ardhys , Sharp Amanda G. , Moore Kathleen , Boothroyd Roger 
Published: March 2021

AbstractTrauma exposure and comorbid substance use are highly prevalent among female drug court participants. Despite the pervasiveness of the issue, few studies have investigated the impact of posttraumatic stress symptoms (PTSS) and nonmedical prescription drug use among this specific population. The present study examined the impact of posttraumatic stress, social support, and nonmedical prescription drug use on graduation outcomes among female participants in a specialized drug court program (N = 210). Participants either received motivational enhancement therapy/cognitive behavioral therapy (MET‐CBT; N = 210) or both MET‐CBT and Seeking Safety through intensive outpatient treatment (n = 109). The findings indicated that graduation was negatively correlated with posttraumatic stress, r = −.19, p = .007, d = 0.40; past 90‐day nonmedical prescription painkiller, opiate, and analgesic use, r = −.19, p = .001, d = 0.44; tangible social support, r = −.24, p = < .001, d = 0.51; and past‐month substance use problems, r = −.25, p < .001, d = .50. In addition, past‐month substance use problems, OR = 0.84, 95% CI [0.72, 0.97]; PTSS, OR = 0.90, 95 % CI [0.82, 0.99]; and tangible social support, OR = 0.94, 95% CI [0.89, 0.98], were significant negative predictors of graduation. These results speak to the importance of facilitating the development of specialized evidence‐based drug court interventions that target and improve comorbid substance use and trauma outcomes among female drug court participants to reduce recidivism and set a precedent for future research to replicate and expand upon these findings.
Featured Front Cover
Authors: Xu Shanshan , Zhao Qinghe , Qin Chengzhe , Qin Mingzhou , Lee Jay , Li Cangyu , Li Yanyan , Yang Jiaxin 
Published: March 2021

The cover image is based on the Original Article Effects of vegetation restoration on accumulation and translocation of heavy metals in post‐mining areas by Mingzhou Qin et al., https://doi.org/10.1002/ldr.3861.
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