bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Beacon Collaborative: A Journey to Excellence
Authors: Hurley Deborah , Gantz Sarah M. , Valcin E. Kate , Sacco Tara L. 
Published: October 2021

Topic
The development of the Critical Care Beacon Collaborative to achieve meaningful recognition.

Clinical Relevance
Recognizing nurses for contributions to their work environment and care delivery is important for their professional and personal fulfillment, job satisfaction, and retention; such recognition can occur at the individual, unit, or organizational level. The American Nurses Credentialing Center’s Magnet Recognition Program acknowledges nursing excellence at the organizational level. It would, however, be difficult for an organization to achieve Magnet designation without nursing excellence at the unit level. To recognize excellence at the unit level, the American Association of Critical-Care Nurses developed the Beacon Award in 2003.

Objective
To describe one academic medical center’s journey toward winning Beacon Awards across 8 units within the adult critical care service.

Content Covered
The Critical Care Beacon Collaborative resulted in a Beacon Award for each unit and important staff outcomes. This article describes the organization, the process before the Critical Care Beacon Collaborative convened and the desired state, and the methods used to achieve our goal. It also discusses unit- and service-level stakeholder involvement. The successes, lessons learned, sustainability, and growth of the Critical Care Beacon Collaborative are shared to assist readers who aspire to pursue a Beacon Award.
Risk Perception and Uptake of Human Papilloma Virus Vaccine among University Students in Jos, Plateau State
Authors: Chingle MP , Bello D , Kefas IB , Okoro B , Nkala C , Gwomson D , Zoakah AI 
Published: October 2021

Background: Human papilloma virus is the most common sexually transmitted viral infection globally. It is a well-established cause of cervical cancer and about 75% of sexually active women and men will acquire this infection at some time in life. This study assessed the risk perception of human papilloma virus infection and its vaccine uptake among university students in Jos, Plateau State Nigeria.
Methods: This was a cross-sectional survey conducted among 300 university students who were selected using a multistage sampling technique. A semi-structured interviewer administered questionnaire was used to assess risk perception and vaccine uptake. Data was analysed using Statistical Package for Social Sciences version 23. Associations between independent and dependent variables were determined using χ2 test while binary logistic regression was used to determine factors associated with risk perception, with significant value set at < 0.05.
Results: Respondents’ awareness of human papilloma virus infection and the vaccine was 148 (49.3%) and 62(20.7%) respectively. Ninety four (31.3%) students had good risk perception of the infection while 206 (68.7%) had poor perception. Three (1.0%) students had taken the vaccine with no statistically significant difference between health and social science students (p = 0.05). Health science students had 3 times better risk perception than social science students (OR = 3.42, 95% CI = 2.03 - 5.77; P< 0.001).
Conclusion: Human papilloma virus infection risk perception and vaccine uptake were poor among Jos University students. There is a need to improve the vaccine uptake through awareness creation and advocacy in Nigeria.
People of the 21st century: Where we came from – Who we are –
Where we are going
Authors: K. Oleś Piotr , Bartnicka-Michalska Aneta 
Published: October 2021

The current culture emphasizes effectiveness and happiness. In this article, we discuss whether it is possible to function optimally in the professional sphere without existential reflection. As we argue, the need for a meaning of life and giving sense to our activity is fundamental. Universal human needs, optimal functioning models, and developmental patterns throughout life support our perspective. The challenges and problems of midlife transition have a common denominator – personalized awareness of life’s finiteness and fear of death. During midlife, people need philosophical reflection on values basic for the meaning of life. Referring to Søren Kierkegaard, culture promotes fixation on the aesthetic stage, while personality development leads to the ethical and religious stage. It means profound transformation, striving for internal integration, and stabilizing the person’s functioning on higher values. Kierkegaard’s philosophical anthropology and existential psychology promote the pattern of conscious, intentional life, and personal growth.
Elite athletes’ mental well-being and life satisfaction: a study of elite athletes’ resilience and social support from an Asian unrecognised National Olympic Committee
Authors: C. H. Kuok Angus , K. I. Chio David , C. H. Pun Alan 
Published: October 2021

IntroductionThis study aimed to investigate elite athletes’ mental well-being, and to ascertain whether the personal factor resilience and the social factor social support can play a role in promoting mental well-being and life satisfaction. In addition, this is one of the first studies to investigate well-being among elite athletes who are from a region belonging to an unrecognised National Olympic Committee and are not eligible to join the Olympic Games.Material and methodsEighty-four full-time elite athletes (37 males, 47 females) with mean age of 22.36 years old participated in this quantitative research study. Formal letters describing the purpose and organiser of the study were sent to the sport entities in Macao asking their permission for the researchers to contact the elite athletes to participate in this study. After gaining the permission, the elite athletes belonging to these entities were approached individually, to inform them of the purpose of the study and receive their consent.ResultsRegression revealed that emotional support and adaptability of resilience were strong positive predictors of mental well-being. Additionally, mental well-being was found to be a strong positive predictor of life satisfaction. The results reflected that in elite athletes possessing high adaptability and receiving more emotional support could help to maintain their mental well-being.ConclusionsImplications (based on the findings) are discussed in order to provide insights for policy makers or coaches how to promote elite athletes’ mental well-being.
КОНСОРЦИУМ МИКРООРГАНИЗМОВ, ИСПОЛЬЗУЕМЫЙ ДЛЯ ПОЛУЧЕНИЯ ПОЛИФУНКЦИОНАЛЬНЫХ БИОПРЕПАРАТОВ С БИОЛОГИЧЕСКОЙ АКТИВНОСТЬЮ
Authors: Kukhar Yelena , Исанов Талгат 
Published: October 2021

Разработка эффективных микробиологических препаратов для сельского хозяйства, представляющих из себя живые клетки микроорганизмов, отобранные по полезным свойствам, становится все более актуальной. Целью исследований являлось создание нового полифункционального консорциума микроорганизмов с высоким уровнем биологической активности, адаптированного к глубинному культивированию и пригодного к получению биопрепаратов.
В статье описываются этапы и результаты исследований по разработке нового полифункционального консорциума микроорганизмов «UMBK-1T» с высоким уровнем биологической активности, характеризующегося постоянством состава популяции, адаптированного к глубинному культивированию.
Авторами изучены культурально-морфологические свойства микроорганизмов, проведено метагеномное NGS-секвенирование, сделан анализ генома, подобраны методы хранения консорциума микроорганизмов. Генетический анализ показал, что микробиом нового пробиотического препарата в основном состоит из микроорганизмов типа Firmicutes (96,42%). Доминирующими видами в сообществе являются Lactobacillus hulgardii – 18,02%, Lactobacillus camelliae – 15,24%, Lactobacillus ramnosus – 11,66% и Saccharomyces cerevisiae – 38,07%. Консорциум микроорганизмов UMBK-1T депонирован в Коллекции микроорганизмов РГП «Республиканская коллекция микроорганизмов» КН МОН РК под номером RKM 0862, ссылка 11LB-1Sc.
На основе консорциума микроорганизмов разработаны пробиотический препарат для повышения эффективности использования кормов в животноводстве и нормализации работы желудочно-кишечного тракта животных; препарат для повышения урожайности комнатных, сельскохозяйственных и лесных культур; биопрепарат для очистки и разделения нефтешламовых загрязнений.
ВЫЧИСЛИТЕЛЬНЫЕ ЭКСПЕРИМЕНТЫ ПО ИССЛЕДОВАНИЮ ДВИЖЕНИЯ ТЕЛА В ПОЛЕ ЦЕНТРАЛЬНОЙ СИЛЫ
Authors: Мукушев Базарбек 
Published: October 2021

Аннотация: В статье проанализированы следующие виды центральных сил: естественные и виртуальные. На основе вычислительных экспериментов исследованы закономерности движения тела в поле этих сил. К естественным силам относятся гравитационные силы материальных точек, электростатические силы притяжения точечных зарядов и квазиупругие силы. Изучены виртуальные центральные силы, которые в зависимости от расстояния не убывают по законы F . Были составлены компьютерные программы в среде ППП Mathcad, необходимые для изучения закономерности движения тел в поле центральных сил.
Evaluation of the parameters of pulse signals applied in electrical stimulation using a new experimental device in the course of Medical and Biological Physics
Authors: Kazushchyk A. L. , Petrova E. S. , Savitsky A. I. , Kulikovich D. B. 
Published: October 2021

Objective. To develop an experimental device, an algorithm for visual and analytical evaluation of the parameters of pulse signals used in electrical stimulation for further application in the course of Medical and Biological Physics.Materials and methods. The data obtained with the help of the experimental device were used as research materials. The analysis of the obtained results (characteristics of the pulse signal) was carried out with the analytical and numerical methods.Results. The proposed experimental device for receiving and analyzing pulse signals applied in electrical stimulation in education allows mastering the methods of the determination of the parameters of pulse signals, studying the methods to alter the characteristics of pulse signals used in electrical stimulation.Conclusion. The application of the experimental device makes it possible to acquire skills to evaluate the parameters and characteristics of difference pulse signals through their visualization and analytical evaluation.
Limited scleroderma: sonographic pattern in the stage of erythema/edema
Authors: Yurkovskiy A. M. , Pаroshуna L. A. , Achinovich S. L. 
Published: October 2021

Objective.To describe the sonopattern of limited scleroderma (LS) in the early stages after the onset of erythema.Materials and methods.The work describes a clinical case of limited plaque scleroderma. The sonographic examination was carried out on an ultrasound scanner using a transducer with operating frequencies of 10–16–18 MHz. Material sampling for the histologic examination of the skin was performed from the area with the most pronounced inﬂammatory changes under sonographic control.Results.It has been found that increased echogenicity of the dermis, “blurring” of the dermis/hypodermis boundary, increased echogenicity and the “stalactite-like” pattern of subcutaneous fat occur in the frst week of the disease; normalization or a signifcant improvement of the sonopattern is noted by the end of the second week or by the beginning of the third week after the onset of erythema.Conclusion.There is a certain parallelism between the histologic and sonographic patterns, which makes it possible to adequately assess both the activity and the stage of the LS process.
Extragonadal mediastinal germ cell tumor
Authors: Tishchenko G. V. , Shalyga A. I. , Tsishchanka I. A. 
Published: October 2021

Extragonadal germ cell tumors (GCTs) are neoplasms that develop from germ cells and have a similar histopathological structure with the gonadal forms of GCTs, but are located outside the gonads. GCTs are the most common malignant neoplasms in men aged 15–35. From 1 to 5 % of malignant GCTs are of the extragonadal origin.The work describes a clinical case of extragonadal mediastinal germ cell tumor, which was diagnosed at the stage of the histological examination of the surgical material.
THE PREVALENCE OF CHRONIC HEPATITIS C IN PATIENTS PRESENTING WITH VAGUE RHEUMATIC SYMPTOMS IN A LOCAL COMMUNITY IN DISTRICT PUNJAB, PAKISTAN
Authors: Sarwar Faheem , Murtaza Ghulam , Javed Sana 
Published: October 2021

Objective:
This study has been conducted to highlight the prevalence of chronic hepatitis in patients presenting with vague symptoms such as generalized body aches and weakness.
Methods:
A cross-sectional study was conducted in Tehsil Headquarter Hospital Sharaqpur, Sheikhupura, Pakistan. During a period of two and a half months, 751 patients presenting to general outdoor department with vague symptoms were selected through random sampling. They were tested for Anti Hepatitis C Virus Antibodies, Hepatitis B Surface Antigen, and Anti Human Immunodeficiency Virus Antibodies with Rapid Immunochromatographic Test Kits. Statistical analysis was performed using IBM SPSS Statistics version 23.
Results:
Of the 751 randomly selected patients, 28 were eliminated due to missing data. Out of 723 included participants, 36% were male and 64% were female with a mean age of 53.11±11.2 years. 26.42% people were screened positive for Hepatitis C (N=191). 1.7% people were screened positive for Hepatitis B (N=13). Whereas only 0.12% (N=1) were HIV positive.
Conclusion:
This study established that Chronic Hepatitis often presents with mild and vague symptoms. Also, the prevalence of HCV is significantly higher in our population in spite of the ongoing hepatitis control programs and is rising in contrast to the global decline.
THE SAFETY OF VEROCELL COVID -19 (SINOPHARM) VACCINATION AMONG HEALTH CARE WORKERS IN KHYBER TEACHING HOSPITAL, PESHAWAR
Authors: Altaf Shandana Altaf , Amer Mariana Amer , Azhar Amer Azhar 
Published: October 2021

Objectives: To determine the safety of Sinopharm Covid -19 vaccine among health care workers of Khyber Teaching Hospital (KTH, Peshawar).
Material and Methods: This observational study was carried out to assess the side effects associated with the first dose of Sinopharm vaccine among health care workers in KTH Peshawar, Pakistan. Data was collected using a close ended questionnaire which was filled by the health care workers above 18 years of age. The participants were asked to monitor any side effects upto 1 week after the first dose of sinopharm vaccine administered to them. Data was analyzed using SPSS version 23 for macbook.
Results: A total of 400 health workers were included in the study but only 155 partcipants responded by completing the questionnaire. It was observed that 63.9% of the participants who were vaccinated experienced at least one symptom after vaccination. The most common symptom was pain at injection site (36.8%) experienced during 15 – 30 minutes after vaccination. The occurrence of symptoms after vaccination was greater in age group 24-42 years which was 60.6% while in age group 43-60 years it was 39.4%. Our analysis shows that there is no association between co-morbidities and post vaccination symptoms (p>0.01).
Conclusion: Our study concludes that sinopharm vaccine has no severe/ moderate side effects and therefore safe for public use.
Key words: Safety, SARS Covid-19, Sinopharm vaccine
Mucosal Immunology
Authors: Sepehrnia Saeed 
Published: October 2021

Approximately 80% of the pathogens that lead to deadly infections in humans choose mucosal tissue as the first site of infection. The mucosal surfaces of the body include the gastrointestinal tract, airways, oral cavity, and urogenital mucosa, which provide a large area conducive to the invasion and accumulation of many microorganisms and are of great importance in this regard. The large extent of mucus, as well as the accumulation of bacteria and countless foreign antigens in these areas, are the most important reasons for the importance of mucosal tissues. In addition to the myriad of symbiotic bacteria, large amounts of oral antigens (both pathogenic and non-pathogenic) enter a person’s body daily and human mucosal tissues are exposed to these antigens. The function of the mucosal immune system is to distinguish pathogenic antigens from non-pathogenic ones. In this way, against a large number of oral antigens or co-tolerant microorganisms, and pathogenic antigens, a favorable (and even non-inflammatory, possible) immune response is produced. Mucosal tissue, as the largest lymphatic organ in the body, is home to 75% of the lymphocyte population and produces the highest amount of immunoglobulin. The amount of secreted IgA (slgA) produced daily by mucosal surfaces is much higher than the IgG produced in the bloodstream. A 70 kg person produces more than 3 grams of IgA per day, which is about 70–60% of the total antibodies produced in the body. The first embryonic organ in which immune system cells are located in the intestine. Some researchers consider this organ (and specifically mucosal lymph nodes) to be the source of the human immune system.
Pseudopolydora (Annelida: Spionidae) from the Arabian Gulf, Kuwait
Authors: Radashevsky Vasily I. , Al-Kandari Manal , Malyar Vasily V. , Pankova Victoria V. 
Published: October 2021

Seven species of Pseudopolydora are described and illustrated from the Arabian Gulf, Kuwait: P. achaeta Radashevsky & Hsieh, 2000, P. antennata (Claparède, 1868), P. arabica Radashevsky & Al-Kandari, 2020, P. auha sp. nov., P. kuwaiti sp. nov., P. melanopalpa sp. nov., and P. multispinosa sp. nov. The morphology of the developed planktonic larvae is described for P. antennata and P. kuwaiti sp. nov. Adults of all species live in tubes in soft sediments, while adults of P. kuwaiti sp. nov. also bore in shells of gastropods and dead corals encrusted by coralline algae. Pseudopolydora antennata and P. arabica form dense settlements up to 50 000 individuals per 1 m2, while other species are comparatively rare. The phylogenetic relationships between the examined species and other Pseudopolydora (18 species in total) were assessed in an analysis of sequence data of four gene fragments: mitochondrial 16S rDNA, nuclear 18S rDNA and 28S rDNA, and Histone 3 (2473 bp in total). Three species complexes are distinguished involving P. antennata, P. diopatra Hsieh, 1992 and P. paucibranchiata (Okuda, 1937). Sets of adult morphological features shared by species of each complex and an identification key to Pseudopolydora species from the Arabian Gulf are provided.
Colorectal cancer biomarkers and their impact on the clinical practice
Authors: Crespo James , Victorino Ana Paula , Araujo Kelly , Araujo Luiz Henrique , Vieira Fernando Meton de Alencar Camara 
Published: October 2021

ABSTRACTColorectal cancer (CRC) holds third place in the global ranking of malignancies worldwide. Patients with CRC commonly show distinct outcomes and treatment responses due to their biological features and tumoral biomarkers. This review explores the repertoire of molecular biomarkers in CRC, comprised of chromosomal aberrations and genomic instability and genetic mutations. We also underline the stratification of CRC patients into four clinically defined subsets: CMS1 (MSI, immune); CMS2 (canonical); CMS3 (metabolic); and CMS4 (mesenchymal), as well as novel techniques to be applied very soon in the field, such as cell-free DNA, tumor mutational burden, and microbiome profiling.
Analysis on complete pathological response and estimated survival among breast cancer patients undergoing neoadjuvant chemotherapy in a private institution in the state of Rio de Janeiro
Authors: Sermoud Letícia Morais C. O , Gaui Maria de Fátima Dias , Ferreira Thamirez de Almeida Vieira , Lerner Lilian Campos , Buscacio Gustavo , Pagnoncelli Dante , Araujo Luiz Henrique 
Published: October 2021

ABSTRACT
Objective: Breast cancer is the most common malignancy among women, both in developed and in developing countries. Indications for neoadjuvant treatment have been expanded so that pathological responses can be evaluated. Diversified therapeutic approaches may thus be indicated in accordance with each residual disease profile. This was a real-life study, in which the aim was to analyze the complete pathological response (CPR) and estimated survival among breast cancer patients undergoing neoadjuvant chemotherapy in a private institution in the state of Rio de Janeiro.
Methods: This was a prospective observational cohort study on patients diagnosed with breast cancer and treated with neoadjuvant chemotherapy, in a private institution. The primary objective of this study was to analyze CPR. As secondary endpoints, we evaluated the disease-free survival (DFS) and overall survival (OS) of these patients and correlated them with clinical-pathological variables.
Results: CPR was achieved in: 12.5% of luminal A cases; 19.5% of luminal B/HER-2-negative cases; 38.5% of luminal B/ HER-2-positive cases; 65% of HER-2-enriched cases; and 37.8% of triple negative cases. There was a significant correlation between CPR and histopathological subtypes (p<0.001). At the end of 36 months, the DFS for patients with CPR was 89.1% vs. 72.4% for the others (p=0.01). OS could not be calculated for patients who achieved CPR, because there was no event.
Conclusion: We confirmed in this study that a correlation exists between CPR and overall survival. In addition, we were able to show that even in developing countries, such as Brazil, appropriate treatments can be offered in accordance with international guidelines, such that our results were consequently similar to those in the worldwide literature.
Hvorfor fortælle dig noget, du allerede ved?
Authors: Christensen Pernille Meyer 
Published: October 2021

Why Tell You Something You Already Know?
– On Second Person Narratives in Danish Literature

In this article, I propose a typology that expands the empirical field of second person narratives to include any narrative, fictional as well as autobiographical, where the “you” is designated, but not addressed. Based on the proposed typology, I investigate the development of second person narratives throughout Danish literary history; from experimental to conventionalized second person narratives.
Des repères pour la conception des apps ?
Authors: Khazaal Yasser , Potvin Stéphane , Pennou Antoine , Djomo William , Borgeat François , Lecomte Tania 
Published: October 2021

Objectif Proposer quelques repères pour faciliter le processus de création d’applications pour téléphones intelligents (apps) en santé mentale.
Méthode Présentation brève de l’intérêt potentiel des apps et proposition argumentée d’étapes clés pour la création des apps. L’article se base sur une revue narrative, un retour d’expérience et des discussions de groupes d’experts.
Résultats Les apps ont des caractéristiques ubiquitaires particulièrement intéressantes pour le domaine de la santé mentale. Potentiellement connectées à de multiples technologies, mobiles et disponibles en tout temps, elles permettent une grande flexibilité de conception. Afin d’augmenter les chances d’efficacité et de bonne dissémination d’une app donnée, certains principes pourraient guider de manière utile le travail de conception des apps : 9 repères sont proposés, en particulier une bonne intégration des utilisateurs finaux autour d’objectifs cibles bien définis durant tout le processus de création de tels outils.
Conclusion Les repères proposés pourraient faciliter le processus de création d’apps pour la santé mentale.