bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rate of Force Development Is Related to Maximal Force and Sit-to-Stand Performance in Men With Stages 3b and 4 Chronic Kidney Disease
Authors: Gollie Jared M. , Harris-Love Michael O. , Patel Samir S. , Shara Nawar M. , Blackman Marc R. 
Published: September 2021

Introduction: The primary aims of the present study were to assess the relationships of early (0–50 ms) and late (100–200 ms) knee extensor rate of force development (RFD) with maximal voluntary force (MVF) and sit-to-stand (STS) performance in participants with chronic kidney disease (CKD) not requiring dialysis.Methods: Thirteen men with CKD (eGFR = 35.17 ±.5 ml/min per 1.73 m2, age = 70.56 ±.4 years) and 12 non-CKD men (REF) (eGFR = 80.31 ± 4.8 ml/min per 1.73 m2, age = 70.22 ±.9 years) performed maximal voluntary isometric contractions to determine MVF and RFD of the knee extensors. RFD was measured at time intervals 0–50 ms (RFD0−50) and 100–200 ms (RFD100−200). STS was measured as the time to complete five repetitions. Measures of rectus femoris grayscale (RF GSL) and muscle thickness (RF MT) were obtained via ultrasonography in the CKD group only. Standardized mean differences (SMD) were used to examine differences between groups. Bivariate relationships were assessed by Pearson's product moment correlation.Results: Knee extensor MVF adjusted for body weight (CKD=17.14 ±.1 N·kg0.67, REF=21.55 ±.3 N·kg0.67, SMD = 0.79) and STS time (CKD = 15.93 ±.4 s, REF = 12.23 ±.7 s, SMD = 1.03) were lower in the CKD group than the REF group. Absolute RFD100−200 was significantly directly related to adjusted MVF in CKD (r = 0.56, p = 0.049) and REF (r = 0.70, p = 0.012), respectively. STS time was significantly inversely related to absolute (r = −0.75, p = 0.008) and relative RFD0−50 (r = −0.65, p = 0.030) in CKD but not REF (r = 0.08, p = 0.797; r = 0.004, p = 0.991). Significant inverse relationships between RF GSL adjusted for adipose tissue thickness and absolute RFD100−200 (r =−0.59, p = 0.042) in CKD were observed.Conclusion: The results of the current study highlight the declines in strength and physical function that occur in older men with CKD stages 3b and 4 not requiring dialysis. Moreover, early RFD was associated with STS time in CKD while late RFD was associated MVF in both CKD and REF.Clinical Trial Registration: ClinicalTrials.gov, identifier: NCT03160326 and NCT02277236.
Use of mHealth Solutions for Improving Access to Adolescents' Sexual and Reproductive Health Services in Resource-Limited Settings: Lessons From Zimbabwe
Authors: Dhakwa Dominica , Mudzengerere Fungai H. , Mpofu Mulamuli , Tachiwenyika Emmanuel , Mudokwani Florence , Ncube Blessing , Pfupajena Mutsa , Nyagura Tendai , Ncube Getrude , Tafuma Taurayi A. 
Published: September 2021

Background:Gaps still exist in reducing new HIV infections among adolescent girls and young women (AGYW) aged 10–24 years. High Internet coverage and mobile phone penetration rates present opportunities for the use of mobile health (mHealth) to support access to health services. We present results of an FHI 360 and Zimbabwe Health Interventions-implemented mHealth intervention for reproductive health (RH) and HIV testing service (HTS) referral among AGYW aged 10–19 years between October 2019 and September 2020.Methods:Adolescent girls and young women referred for RH and HTS under the Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe (DREAMS) program had automatic reminders sent to their phones to facilitate access to services through short message service (SMS) and also using a paper-based system. These data were captured in a web-based District Health Information System (DHIS) database, which captured the referral completion status of the AGYW. Data for AGYW referred for RH and HTS for the period October 2018 to September 2019 for the paper-based system and October 2018 to September 2020 for the mHealth were extracted from District Health Information System version 2 (DHIS2) database and analyzed using SPSS to generate descriptive statistics. The Chi-square test was used to assess differences in referral completion rates by age-group; marital status, district, and type of service, as well as differences between mHealth and paper-based referral completion rates within each of the groups for the variables above.Results:A total of 8,800 AGYW referred for RH and HTS, where 4,355 and 4,445 were referred through the mHealth and paper-based systems, respectively. About 95.2% (4,148/4,355) and 87.8% (3,903/4,445) referred through mHealth and the paper-based system, respectively completed referrals. The median time for referral completion was 1 day (Range = 0–9 days) for mHealth and 11 days (Range = 0–28 days) for the paper-based system. AGYW referred through mHealth were 17.995 timesmore likely to complete the referral system than those referred through the paper-based system (OR =17.995;p&lt;0.001).Conclusion:Compared to the paper-based referral system the mHealth solution resulted in a higher, service referral completion rates and shorter turnaround time. We recommend expansion of the mHealth solution to all DREAMS supported districts to increase uptake of RH and HTS among AGYW aged 10–19 years.
Field (In)dependence Flexibility Following a Virtual Immersion Is Associated With Cybersickness and Sense of Presence
Authors: Maneuvrier A. , Decker L. M. , Renaud P. , Ceyte G. , Ceyte H. 
Published: September 2021

Field dependence–independence (FDI) is a psychological construct determining an individual’s approach of the perception–cognition coupling. In virtual reality (VR) context, several studies suggest that an individual’s perceptive style is susceptible to shift toward a more FI mode through down-weighting of conflicting visual cues. The present study proposes to investigate the potential flexible nature of FDI following a virtual immersion and to assess if this flexibility might be associated with the subjective experience of VR. 86 participants explored a real-world–like virtual environment for approximately 10 min. FDI levels were measured before and after the VR exposure using the rod-and-frame test. Their subjective experience of VR was measured a posteriori (cybersickness and sense of presence) and used in order to build two experimental groups via a cluster analysis. The results showed that only participants with a poor subjective experience of VR (i.e., a low level of sense of presence associated with a high level of cybersickness) significantly shifted to a more FI mode, which is discussed as a sensory re-weighting mechanism. Pragmatical applications are discussed, and future studies are outlined, based on the conclusion that FDI might be more flexible than we thought, which could shed light on the psychophysiology of VR.
Fourth Branchial Anomalies: Diagnosis, Treatment, and Long-Term Outcome
Authors: Boonen Annelien , Hens Greet , Meulemans Jeroen , Hermans Robert , Delaere Pierre , Vander Poorten Vincent 
Published: September 2021

Introduction: Fourth branchial anomalies, the rarest among anomalies of the branchial apparatus, often present diagnostic and therapeutic challenges. We evaluated the clinical presentation and radiographic features, the treatment and the long-term outcome of patients in this setting.Patients and Methods: Of 12 patients treated in the University Hospitals Leuven from 2004 until 2020, 12 variables were collected: date of birth, gender, age of onset of the symptoms, age at final diagnosis, presentation, laterality, previous procedures, diagnostic tools, treatment (open neck surgery, endoscopic laser excision, or combination), complications, recurrence, and period of follow-up. Descriptive statistics were calculated and results were compared to the existing literature.Results: The most common clinical manifestations were recurrent neck infections with and without abcedation. Definitive diagnosis using direct laryngoscopy, visualizing the internal sinus opening, was possible in all patients. A CT study revealed the typical features of fourth branchial anomalies in seven patients out of nine, an ultrasound study in five out of nine patients. All patients underwent open neck surgery. If this was insufficient, secondary endoscopic laser resection of the ostium at the apex of the piriform sinus was performed (n = 4). In eight patients a thyroid lobectomy was needed for safe complete resection. Postoperative complications were minimal and at long-term, none of the patients showed further recurrence. Average time of follow-up was 8.6 years.Conclusions: Direct laryngoscopy and CT are the most accurate diagnostic tools. Our recommended treatment schedule consists of complete excision of the sinus tract by open neck surgery as the primary treatment because this ensures the best results. In case of recurrence afterwards, endoscopic laser resection of the pharyngeal ostium solved the problem.
Clinical Validation of an Immune Quiescence Gene Expression Signature in Kidney Transplantation
Authors: Akalin Enver , Weir Matthew R. , Bunnapradist Suphamai , Brennan Daniel C. , Delos Santos Rowena , Langone Anthony , Djamali Arjang , Xu Hua , Jin Xia , Dholakia Sham , Woodward Robert N. , Bromberg Jonathan S. 
Published: September 2021

Key Points

AlloMap Kidney is a gene expression profile developed using candidate genes from the AlloMap assay broadly used in heart transplantation.AlloMap Kidney was validated to differentiate quiescence from rejection in two independent sample sets using a quantitative scale.Blood cell gene expression and donor-derived cell-free DNA contribute independent signals and inform on different aspects of allograft rejection.

Background
Despite advances in immune suppression, kidney allograft rejection and other injuries remain a significant clinical concern, particularly with regards to long-term allograft survival. Evaluation of immune activity can provide information about rejection status and help guide interventions to extend allograft life. Here, we describe the validation of a blood gene expression classifier developed to differentiate immune quiescence from both T cell–mediated rejection (TCMR) and antibody-mediated rejection (ABMR).

Methods
A five-gene classifier (DCAF12, MARCH8, FLT3, IL1R2, and PDCD1) was developed on 56 peripheral blood samples and validated on two sample sets independent of the training cohort. The primary validation set comprised 98 quiescence samples and 18 rejection samples: seven TCMR, ten ABMR, and one mixed rejection. The second validation set included eight quiescence and 11 rejection samples: seven TCMR, two ABMR, and two mixed rejection. AlloSure donor-derived cell-free DNA (dd-cfDNA) was also evaluated.

Results
AlloMap Kidney classifier scores in the primary validation set differed significantly between quiescence (median, 9.49; IQR, 7.68–11.53) and rejection (median, 13.09; IQR, 11.25–15.28), with P<0.001. In the second validation set, the cohorts were statistically different (P=0.03) and the medians were similar to the primary validation set. The AUC for discriminating rejection from quiescence was 0.786 for the primary validation and 0.800 for the second validation. AlloMap Kidney results were not significantly correlated with AlloSure, although both were elevated in rejection. The ability to discriminate rejection from quiescence was improved when AlloSure and AlloMap Kidney were used together (AUC, 0.894).

Conclusion
Validation of AlloMap Kidney demonstrated the ability to differentiate between rejection and immune quiescence using a range of scores. The diagnostic performance suggests that assessment of the mechanisms of immunologic activity is complementary to allograft injury information derived from AlloSure dd-cfDNA. Together, these biomarkers offer a more comprehensive assessment of allograft health and immune quiescence.
Effectiveness of Cooperative Learning with Advisor Group Strategy in 7th Grade Mathematics Classroom
Authors: Asrina  , Arsyad Nurdin , Arwadi Fajar 
Published: September 2021

This study aims to determine the Effectiveness of the Cooperative Learning Model with Group Advisory Strategy in Mathematics Learning of the Grade VII SMP. This research is pre-experiment with techniques sampling is cluster random sampling. Data collection was carried out using observation sheets of implementation of learning, test results of learning (pretest and posttest), observation sheets of student activities, and student questionnaire responses. The data analysis technique used is descriptive and inferential statistical analysis. The results of descriptive statistical analysis showed: (1) The average score of learning outcomes after learning reaches 80.04 with standard deviation of 8.79, (2) the posttest results show that classical completeness is achieved 91% (3) The average percentage of student activity is 89% (4) the average percentage of students who gave positive response 89%. The results of inferential statistical analysis showed : (1) The average value of students taught using cooperative learning models with the Advisor Group Strategy is greater than completeness, which is 70, and (2) The proportion of classical completeness of learning outcomes after the application of the cooperative learning model with Group Advisors Strategy achieve classical completeness. From the results of this research it can be concluded that cooperative learning models with the Group Advisory Strategy are effectively used in students of grade VII.
Forced Displacement during the Syrian Forced Displacement during the Syrian Crisis, and its Impact on Jaramana’s Children's Education: A Field Study , and its Impact on Jaramana’s Children's Education: A Field Study
Authors: Rehawi Jalb Nihal Abdulsalam , Al-Rebdawi Qassem 
Published: September 2021

The study aims to examine the problem of forced displacement and its social and economic problems in light of the Syrian crisis. Such an aim helps to know the difficulties and challenges facing the children of displaced families in learning, and the reasons for their lack of enrolment. It also clarifies whether there are significant statistical differences at among the attitudes of the children of the displaced families towards education regarding the following variables: (the work of the head of the family, the economic level of the family, and the work of the children). The study has adopted the descriptive-analytical approach; a questionnaire was adopted as a tool to collect information. The study was applied to a sample of displaced families in Jaramana City in the governorate of Damascus countryside. The sample consisted of sixty items that represent 40% of the displaced families. Results have shown that the largest percentage of the social and economic problems that the displaced families suffer from is due to the high rents of houses and apartments, and to the high prices and the inability to purchase the basic needs. There are statistically significant differences between the attitudes of the children of the displaced families towards education due to the variable of work of the head of the family, and to the variable of the economic level. For the family, the study has recommended, in light of its findings, several recommendations, including: Enacting temporary laws for the displaced families that include: educating their children, giving priority to employing the members of these families, providing them with houses, and granting them easy and interest-free loans that enable them to buy a house or repair their homes when they return to their liberated from terror areas.
The Degree of Knowledge and Use of Authentic Assessment Tools by Basic Elementary Teachers' According to some Variables
Authors: Joma Amjad , Joma Amjad , Al Soudi Sharif , Alalawi Salma 
Published: September 2021

Evaluation is one of the most important elements of teaching process. The recent trends in evaluation and educational reform movements have called for using alternative evaluation, which focuses on performance evaluation. Authentic assessment is usually described as formative, in which students participate in their acquisition, in addition to the fact that students are productive and active, which is reflected in the students' achievement and skill level. The study aims to reveal the degree of knowledge and use of alternative assessment tools by primary school teachers in Gaza -Palestine. To meet the objective of the study, the researchers used the descriptive-analytical method and the questioner as a study tool. The study sample consisted of (134) elementary basic school teachers in the Gaza governorate in Palestine. Results have shown that the percentage of knowledge of alternative evaluation tools reached (77.7%), which is a high level, and that the percentage of using alternative evaluation tools reached (70.3%). As it is seen, the percentages do not vary according to variables, such as: gender, educational qualification, specialization, classes taught by the teacher, years of service, type of school, gender of school students, educational region, and taking training courses. Howerver, the degree of usage of such alternative tools varies in favour of basic education. The study recommends continuing to motivate primary school teachers to employ alternative assessment tools, and to support them with courses and workshops that enhance their skills in employing these tools
METODOLOGIAS ATIVAS E DIALOGICIDADE NA DIFUSÃO DAS BASES DA EDUCAÇÃO PROFISSIONAL E TECNOLÓGICA
Authors: Diemer Odair , Moraes Átila Alixandre de 
Published: September 2021

Ingressantes dos Institutos Federais e a comunidade em geral apresentam divergência de compreensão sobre o que seria a Educação Profissional e Tecnológica (EPT). Assim, a pesquisa teve como objetivo analisar se metodologias ativas e dialogicidade podem contribuir para a difusão das bases que norteiam a EPT no Brasil. Para a realização da pesquisa foi ofertado ao público em geral uma formação fundamentada em metodologias ativas e dialogicidade sobre as bases que norteiam a EPT, sendo aplicada no IFMS campus Coxim. Durante a formação os participantes registraram suas impressões e opiniões em um diário reflexivo e em anotações de relatos para análise de conteúdo temática. Em síntese, houve indicativos que a metodologia utilizada colaborou com o entendimento e difusão das bases da EPT.
Sosialisasi Kelas LIBUR (Kelas Ibu Balita Gibur) tentang Pemberian Makanan Tambahan pada Bayi Balita Gizi Buruk dan Kurang di Puskesmas Jenggot Kota Pekalongan
Authors: Meikawati Pedvin Ratna , Maslikhah Maslikhah 
Published: September 2021

Toddler age (under five years) is an important period in the process of human growth and development, where in this period growth and development takes place very quickly. The process of growth and development of children that takes place quickly brings the consequences of increasing nutritional needs that are adequate. Poor nutrition is one of the factors that is significantly associated with an increased risk of acute respiratory infections, diarrhea, measles and several other infectious diseases. Such conditions will further worsen the nutritional status of children. If this continues, the risk of death in children will increase.
Based on the Nutrition Program Report at the Pekalongan City Jenggot Health Center, in 2018 there were 13 infants with poor nutritional status 9 (BB / U) with 1 toddler with very thin nutritional status (BB / TB). This shows that there are still many children under five suffering from malnutrition (BB / U) and need special handling in overcoming this. This community service activity aims to increase the knowledge, attitudes and practices of toddlers about malnutrition and to compile healthy foods or snacks. Pretest and posttest were conducted to find out the knowledge of mothers who have babies and toddlers with poor and malnourished status. The results obtained are an increase in knowledge both mothers of children under five who after being given treatment, which was originally 33.3% to 60%. Routine Puskesmas to conduct classes for toddlers with varied in delivery, Academics or other related institutions, to always provide counseling for mothers of toddlers
Menjaga Kesehatan Mental Keluarga saat Pembatasan Sosial Berskala Besar pada Masa Pandemi Covid-19
Authors: Furwasyih Dian , Sunesni Sunesni , Arifin Yulia , Supri Rahmayeni , Zalmawita Widya , Riska Miftah Dwi 
Published: September 2021

The outbreak of the COVID-19 coronavirus infection that has spread throughout the world has had a major impact on the health of the global community, including mental health. Stress that arises during the COVID-19 pandemic could be in the form of fear and anxiety about personal health and the health of other loved ones, changes in sleep and diet patterns, aggravating physical conditions, especially in someone with chronic illness. This activity is one solution that is expected to broaden the audience's insight about maintaining the mental health of families during the COVID-19 pandemic. This activity is carried out through CISCO WEBEX Meeting media. The outputof this activity was the increase of level of knowledge of the audiences 37.5%, the publication of activities on youtube media and publication articles in a journal.
PENGEMBANGAN MEDIA PERMAINAN CATUR RANGKA MATERI SISTEM GERAK MANUSIA MUATAN IPA KELAS V SEKOLAH DASAR
Authors: Kencana Rachmadina Tri , Usman Herlina , Sekaringtyas Tunjungsari 
Published: September 2021

The use of media is one of the essential aspects of the learning process, because, it will provide a different and certainly more varied learning experience so that it will attract students and make it easier to understand the learning material. This research and development aims to produce a learning media to make it easier for students to understand learning material, especially on the material of human locomotor organs system in a fun way. Learning will be meaningful for students if the media used is the appropriate one. The methodology in this research is Research an Development (RND). The type of model used in the ASSURE development model, which consist of 6 stages including analyze learner; state objectives; select methods, media and materials; utilize media and materials; require learner participation; and evaluate and revise. The final results of this research produces a learning media that is useful to support the learning process on the material of human movement organs. The data collection technique used in this study was through observation, interviews, and questionnaires. This research was conducted only to the stage of expert validation to test the feasibility of the product. The product feasibility test involves 3 experts, namely media experts, material experts, and language experts. The results obtained from the three experts if the average is 4.5 from the maximum value of 5, or if converted in percentage is 90%, which means the media is included in the very good category. This shows that the framework of the chess game media is suitable for use in science learning material for human llocomotor organs system.
NILAI KARAKTER DARI DONGENG ANAK PADA MAJALAH BOBO DAN IMPLEMENTASINYA DI MASA PANDEMI COVID-19
Authors: Rizam Masyithah Maghfirah 
Published: September 2021

Children's fairy tales are a literary art that presents children's favorite entertainment and there is knowledge to increase children's knowledge. Children's fairy tales are a way to instill five main values in strengthening character education. It must be known, namely religious values, nationalism, integrity, independence, and mutual cooperation. This research was a qualitative research by describing the five main values of character education in the children’s fairy tale on bobo.grid.id and its implementation in learning during the Covid-19 pandemic. The researcher as the key instrument carried out heuristic and hermeneutic readings to find and describe the main values of character education, namely religious, nationalist, integrity, independent, and mutual cooperation values in Bobo children's fairy tales. The results show that there are five main values of character education in children's fairy tales on bobo.grid.id that can be implemented in learning during the Covid-19 pandemic such as praying to God so that the pandemic will end soon and protocols comply with the safety of self and others.