bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strategi Komuikasi Dakwah Ustadz Muhammad Sholeh Drehem
Authors: Nugroho Adityo 
Published: June 2021

ABSTRACTIn dakwah communication, as a communicator a preacher should have methods or ways so that the message could be delivered to the Jamaah. Ustadz Muhammad Sholeh Drehem delivers his speech throughÂ radios andÂ medias, he has more than other speakers who deliver their preach daily at Ar Rahmah Perak Surabaya, his strategy draws attention to researcher to conduct the research about what kind of strategy or ways implemented by Ustadz Muhammad Sholeh DrehemÂ to deliver his preach and how he overcomes the problems he faces.The purpose of this reseach is to find out whatÂ communication strategy implemented by Ustadz Muhammad Sholeh Drehem at Ar Rahmah mosque, how Ustadz faced his problems. This reseach is a qualitive descriptive kind of reseach which uses three techniques of data collection, through observation, interview, and documentation. The conclusion of the reseach are that Ustadzâ€™s strategy target determination, the determinstion of ways in communication, identification of the jamaahs, source credibility, the Jamaahâ€™s history and feelings, also the media election are quite well. Yet there are problems still, psychology problem, anthropological problem, semantic problem, mechanical problem, and ecological problem.ABSTRAKDalam komunikasi dakwah, seorang daâ€™i adalah sebagai komunikator dakwah diharuskan mempunyai metode atau cara supaya pesan dakwahnya dapat diterima dengan baik oleh jamaâ€™ah atau madâ€™unya. Ustadz Muhammad Sholeh Drehem berdakwah dengan menyampaikan pesan dakwahnya melalui kajian di dalam dan diluar masjid, beliau juga menyampaikan pesan dakwahnya melalui radio, dan media lainnya. Ustadz memiliki jamaâ€™ah yang lebih banyak dibandingkan dengan pengisi kajian rutin lainnya di Masjid Ar Rahmah Perak Surabaya. Hal inilah yang menarik perhatian peneliti untuk menelusuri tentang bagaimana strategi komunikasi dakwah Ustadz Muhammad Sholeh Drehem dan apa hambatan hambatannya.Penelitian ini bertujuan untuk mengetahui apa saja strategi komunikasi yang di lakukan oleh Ustadz Muhammad Sholeh Drehem di masjid Ar Rahmah dan bagaimana Ustadz Muhammad Sholeh Drehem dalam menghadapi hambatan hambatan dakwahnya. Penelitian ini merupakan penelitian diskriptif kualitatif dengan menggunkan tiga teknik pengumpulan data, melalui observasi, wawancara dan dokumentasi. Hasil penelitian memperoleh kesimpulan bahwa strategi Ustadz Muhammad Sholeh Drehem penentuan sasaran, penentuan cara berkomunikasi, kredebilitas sumber, mengidentifikasi jamaâ€™ah, latar belakang jamaâ€™ah, perasaan jamaâ€™ah, pemilihan media. Adapun hambatannya yaitu hambatan psikologis, hambatan antropologis, hambatan simantik, hambatan mikanis, hambatan ekologis
Introduction: Ruminations on the “F” and “B” Words
Authors: Shannon Timothy J. 
Published: June 2021

Abstract
Over the past two decades, historians studying the American West have embraced the label “borderlands” as a means of distinguishing their work from the triumphalism associated with Frederick Jackson Turner’s frontier thesis. Historians of early America have made a similar transition, although the term “frontier” is still very much in use among those working in the mid-Atlantic region. The articles in this special issue of Pennsylvania History illustrate how the themes of borderlands history have found their way into studies of eighteenth-century Pennsylvania, even if the term itself has not gained wide currency there.
Antibiotic Resistant Profile of Lactic Acid Bacteria Isolated from Swine and Poultry Faeces in Umuahia Metropolis
Authors: Osaro-Matthew R. C. , Nweke O. G. 
Published: June 2021

Aim: This study’s aim was to determine the antibiotics resistant profile of lactic acid bacteria isolated from poultry and swine faeces.
Study design: Faecal samples from swine and birds were randomly collected from livestock and poultry farms located in Umuahia metropolis, Abia State.
Place and duration of study: Department of microbiology, Michael Okpara University of Agriculture Umudike, between January 2019 to August 2019.
Methodology: A total of 12 faecal samples, 6 each from swines and birds were examined for the presence of lactic acid bacteria using Deman Rogosa Sharpe agar supplemented with 0.3% CaCO3 (w/v). Isolates were identified based on their physiological and biochemical characteristics. Antibiotic susceptibility was carried out using disk diffusion method.
Results: Of the 12 faecal samples examined, all were positive for lactic acid bacteria, with counts ranging from 1.74 – 2.36 x 106 in swine and 1.52 – 2.08 x 106 in birds. Total of 14 strains that belong to three genera; Lactobacillus, Lactococcus and Streptococcus were isolated, genus Lactobacillus occurred highest 8(57.1%). The isolates showed multidrug resistance and exhibited high rate of resistance to Augmentin (100%), Ceftazidime (100%), Cefotaxime (92.9%), Erythromycin (85.7%), Ceftriaxone (71.4%) and Azithromycin (71.4%).
Conclusion: The antibiotic resistance pattern of the isolated lactic acid bacteria is a clear indication that most animal farmers are misusing antibiotics. Therefore, animal farmers should be advised on antibiotic application safety measures.
Role of Endoscopic Ultrasound in the Diagnosis of Solid Pancreatic Lesions: A Prospective Study
Authors: Elgawish Mahmoud Abdelhamid , Elnady Mohamed Ali Ahmed , Elbedewy Tamer Abd Elhamid , Elbedewy Mohamed Mohamed 
Published: June 2021

Background: Endoscopic ultrasonography (EUS) provides high-resolution images of the pancreas, and it is considered one of the most accurate methods for the diagnosis and staging of solid pancreatic lesions (SPL), EUS guided fine-needle aspiration (EUS–FNA) can obtain cytological samples of pancreatic lesions, making a pathologic diagnosis possible, however, it is associated with small, but not insignificant, morbidity. The aim of this work is to determine in a prospective study, the role of EUS in the diagnosis of SPL in comparison with different radiological studies and to determine the diagnostic value of EUS guided FNA and elastography in differentiation between benign and malignant pancreatic lesions.
Patients and methods: A total of 50 patients with SPL identified by EUS after imaging studies were enrolled in the study. The qualitative elastography score was done, also the semi quantitative score of elastography was represented by the strain ratio (SR) method where two areas were selected, area (A) representing the region of interest and area (B) representing the normal area. Area (B) was then divided by area (A). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated by comparing diagnosis made by elastography, SR with the final diagnosis (by EUS-FNA, surgery, and/or follow up for 6 months).
Results: SPL were found to be malignant in 38 patients and benign in 12 patients. SPL was diagnosed by different imaging modalities in 39 patients with a percentage of (78%), while it was diagnosed by EUS in all 50 patients with a percentage of (100%). Elastography score alone had a sensitivity of 89.4%, a specificity of 75%, a PPV of 91.8% and an NPV of 69.2% and an accuracy of 86%. The best cut-off level of SR to obtain the maximal area under the curve was 8.42 with a sensitivity of 92.1%, specificity of 83.3%, PPV of 94.6%, NPV of 76.9% and an accuracy of 93.1%. Adding both elastography score to SR resulted in a sensitivity of 94.7%, specificity of 83.3%, PPV of 94.7%, NPV of 83.3% and accuracy of 94.3% for the diagnosis of SPL.
Conclusion: EUS has a role in diagnosis of SPL which may be superior to different radiological studies; also, EUS-elastography and SR can be a valuable complementary supplement for EUS-FNA.
Quantum Memory
Authors: Bashkansky Mark , Black Adam T. , Kwolek Jonathan M. , Kuzmich Alex 
Published: June 2021

Abstract
Quantum Memory (QM) commonly refers to a system that reversibly transfers quantum states between a material storage system and a propagating electromagnetic field. It represents a key component in quantum information science and technology.
Over the past 25 years, a wide range of theoretical protocols and experimental approaches to QM has been studied. These include optical delays, mechanical resonators, topological approaches, solid state spins, trapped single atoms and ions, and atomic ensembles.
New applications of QM are being investigated and discovered all the time, including quantum computation, long‐distance entanglement distribution, quantum teleportation, and long‐distance quantum key distribution.
Challenges to the implementation of QM include inefficiencies in storing and recovering the quantum state, and decoherence, which usually manifests by environment‐induced dephasing.
In this monograph we describe, in general terms, methods and protocols that are used in many forms of QM. We also discuss the various experimental systems in which QM has been demonstrated or proposed. Additionally, we discuss the applications of QM that have been identified and progress made in implementing those applications.
Biological Function of Solanaceous Withanolides and Their Effects on Herbivorous Insects
Authors: Sell Marie Pauline , Amezian Dries , Heckel David G. , Pauchet Yannick 
Published: June 2021

Abstract

Naturally occurring withanolides are secondary metabolites with interesting biological activities in vivo and in vitro. The role of withanolide production in plants is still conjectural though numerous studies strongly indicate a potent feeding deterrent effect against insects and other herbivores. In contrast to the potential medical applications of withanolides, the ecological effects on herbivores have not been studied intensively. In this article, we collect and summarise present studies on herbivore–plant interactions in the light of potential insecticidal functions of withanolides. Moreover, taking the case of the specialist noctuid moth
Chloridea
(
Heliothis
)
subflexa
, we not only illustrate the known negative effects of these compounds seem to have on herbivorous insect species but also discuss how
C. subflexa
larvae might benefit from adaptation to their host plants in the genus
Physalis
. Further, we describe potential activation and detoxification mechanisms based on the current state of knowledge.
Correlating Nanocrystalline Structure with Electronic Properties in 2D Platinum Diselenide
Authors: Lukas Sebastian , Hartwig Oliver , Prechtl Maximilian , Capraro Giovanna , Bolten Jens , Meledin Alexander , Mayer Joachim , Neumaier Daniel , Kataria Satender , Duesberg Georg S. , Lemme Max C. 
Published: June 2021

AbstractPlatinum diselenide (PtSe2) is a 2D material with outstanding electronic and piezoresistive properties. The material can be grown at low temperatures in a scalable manner, which makes it extremely appealing for many potential electronics, photonics, and sensing applications. Here, the nanocrystalline structure of different PtSe2 thin films grown by thermally assisted conversion (TAC) is investigated and is correlated with their electronic and piezoresistive properties. Scanning transmission electron microscopy for structural analysis, X‐ray photoelectron spectroscopy (XPS) for chemical analysis, and Raman spectroscopy for phase identification are used. Electronic devices are fabricated using transferred PtSe2 films for electrical characterization and piezoresistive gauge factor measurements. The variations of crystallite size and their orientations are found to have a strong correlation with the electronic and piezoresistive properties of the films, especially the sheet resistivity and the effective charge carrier mobility. The findings may pave the way for tuning and optimizing the properties of TAC‐grown PtSe2 toward numerous applications.
Sphere‐on‐Tube Biomimetic Hierarchical Nanostructures Coupled with Engineered Surfaces for Enhanced Photoelectrochemical Biosensing of Cancer Cells Expressing Folate Receptors
Authors: Gao Ning , Wang Xueying , Feng Jinhui , Li Xiaojian , Wang Huan , Fan Dawei , Zhang Yong , Ma Hongmin , Wei Qin , Ju Huangxian 
Published: June 2021

AbstractThe quantitative detection of cancer cells and the evaluation of folate receptor (FR) expression on cell membranes are of great significance for tumor‐related research. In this work, a photoelectrochemical (PEC) biosensing interface is proposed for detection of cancer cells based on the construction of nanostructured platforms coupled with surface engineering. A “sphere‐on‐tube” hierarchical nanostructure is fabricated by depositing biomimetic polydopamine nanospheres on TiO2 nanotube arrays. Enhanced PEC responses are achieved with the formation of polyethylene glycol antifouling layers and the immobilization of folic acid as a recognition ligand. Based on the ligand–receptor interaction, the antifouling PEC biosensor exhibits a wide linear range for the detection of the breast cancer cell line MDA‐MB‐231 from 20 to 2.0 × 106 cells mL−1 with a low detection limit of 15 cells mL−1 (S/N = 3). The expressing differentiation of FR on several cancer cells is well discriminated. The proposed PEC cytosensing method shows great potential in detection of cancer cells expressing folate receptors.
Engineering Gene Therapy: Advances and Barriers
Authors: Shahryari Alireza , Burtscher Ingo , Nazari Zahra , Lickert Heiko 
Published: June 2021

AbstractCurrently, 33 gene‐therapy drugs/products have been approved in the clinic. Over 3000 completed and ongoing clinical gene therapy trials have been reported worldwide. The development/maturation of tools for gene manipulation and gene delivery, as well as molecular advances in the diagnosis of genetic diseases, have played a central role in gene therapy, which have greatly revolutionized the field. Versatile and diverse genetic tools for gene manipulations and deliveries, with the possibility of short and long‐term effects, are vital advantages of gene therapy tools, paving the road for the development of new therapies. However, efficacy and safety concerns, immune system responses, laborious approaches for developing and manufacturing, unknown gene‐therapy drug interactions with the host and the high cost of drugs/products, are significant barriers in gene therapy. Here, the authors review the attempts for engineering of the gene manipulations that have been undertaken in the last three decades and used in clinical trials focusing on 1) gene‐editing platforms, 2) viral gene delivery systems, and 3) nonviral gene tools. In this comprehensive review, the principles of these gene manipulation tools as well as advances and barriers for their application in modern therapies are discussed. Furthermore, trends and future directions in gene therapy are discussed.
Engineering the Immune Adaptor Protein STING as a Functional Carrier
Authors: Sun Xin , Ni Yun , He Yanpu , Yang Mengdi , Tani Tetsuo , Kitajima Shunsuke , Barbie David A. , Li Jiahe 
Published: June 2021

AbstractActivation of the stimulator of interferon genes (STING) pathway through cyclic dinucleotides (CDNs) is being explored as potent vaccine adjuvants against infectious diseases and to increase tumor immunogenicity toward cancer immunotherapy. To date, a myriad of synthetic vehicles, including liposomes, polymers, and other nanoparticle platforms, have been developed to improve the bioavailability and therapeutic efficacy of STING agonists in preclinical mouse models. Compared to synthetic materials, protein‐based carriers represent an attractive delivery platform owing to their biocompatibility, amenability to genetic engineering, and intrinsic capacity to form well‐defined structures. Here, the immune adaptor STING is engineered as aprotein‐based delivery system for efficient encapsulation and intracellular delivery of CDNs. Through genetic fusion with a protein transduction domain, the recombinant STING can spontaneously penetrate cells to markedly enhance the delivery of CDNs in a mouse vaccination model and a syngeneic melanoma model. As certain tumor cells can evade immune surveillance via loss of STING expression, authors further unveiled that the STING platform can serve as a functional vehicle to restore the STING signaling in cell lines with impaired STING expression. Altogether, their delivery platform may offer a unique direction toward targeting STING‐silenced tumors and augmenting the efficacy of STING‐based vaccine adjuvants.
Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease
Authors: Zhang Xiaoling , Farrell John J. , Tong Tong , Hu Junming , Zhu Congcong ,   Alzheimer's Disease Sequencing Project, Wang Li‐San , Mayeux Richard , Haines Jonathan L. , Pericak‐Vance Margaret A. , Schellenberg Gerard D. , Lunetta Kathryn L. , Farrer Lindsay A. 
Published: June 2021

AbstractIntroductionFindings regarding the association between mitochondrial DNA (mtDNA) variants and Alzheimer's disease (AD) are inconsistent.MethodsWe developed a pipeline for accurate assembly and variant calling in mitochondrial genomes embedded within whole exome sequences (WES) from 10,831 participants from the Alzheimer's Disease Sequencing Project (ADSP). Association of AD risk was evaluated with each mtDNA variant and variants located in 1158 nuclear genes related to mitochondrial function using the SCORE test. Gene‐based tests were performed using SKAT‐O.ResultsAnalysis of 4220 mtDNA variants revealed study‐wide significant association of AD with a rare MT‐ND4L variant (rs28709356 C>T; minor allele frequency = 0.002; P = 7.3 × 10−5) as well as with MT‐ND4L in a gene‐based test (P = 6.71 × 10−5). Significant association was also observed with a MT‐related nuclear gene, TAMM41, in a gene‐based test (P = 2.7 × 10−5). The expression of TAMM41 was lower in AD cases than controls (P = .00046) or mild cognitive impairment cases (P = .03).DiscussionSignificant findings in MT‐ND4L and TAMM41 provide evidence for a role of mitochondria in AD.
Fluoreszenz‐detektierte Pump‐Probe‐Spektroskopie
Authors: Malý Pavel , Brixner Tobias 
Published: June 2021

AbstractFluoreszenzdetektierte Pump‐Probe‐(F‐PP‐)Spektroskopie überwindet einige Einschränkungen der traditionellen PP‐Spektroskopie. F‐PP unterdrückt die Absorption angeregter Zustände, bietet eine untergrundfreie Detektion, entfernt Artefakte, die aus der Anregepuls‐Streuung, aus nicht‐resonanter Lösungsmittelantwort oder aus kohärenter Pulsüberlappung resultieren, und erlaubt eine Extrahierung der Dynamik angeregter Zustände unter bestimmten Bedingungen. Trotz inkohärenter Detektion ist die zeitliche Auflösung von F‐PP durch die Dauer der Laserpulse gegeben und unabhängig von der Fluoreszenzlebensdauer. Wir beschreiben das Funktionsprinzip von F‐PP und liefern eine theoretische Beschreibung. Zudem veranschaulichen wir spezifische Eigenschaften von F‐PP im direkten Vergleich mit PP. Zu diesem Zweck untersuchen wir mittels beider Techniken ein molekulares Squarain‐Heterodimer, Kern‐Schale‐CdSe/ZnS‐Quantenpunkte sowie das fluoreszierende Protein mCherry. F‐PP ist umfassend anwendbar auf chemische Systeme in verschiedensten Umgebungen und in unterschiedlichen Spektralbereichen.
Synergetic Metal Defect and Surface Chemical Reconstruction into NiCo2S4/ZnS Heterojunction to Achieve Outstanding Oxygen Evolution Performance
Authors: Sun Jing , Xue Hui , Guo Niankun , Song Tianshan , Hao Yi‐ru , Sun Jiawen , Zhang Jiangwei , Wang Qin 
Published: June 2021

AbstractDefect and interface engineering are recognized as effective strategies to regulate electronic structure and improve activity of metal sulfide. However, the practical application of sulfide is restricted by their low conductivity and rapid decline in activity derived from large volume fluctuation during electrocatalysis process. More importantly, the determination of exact active site of sulfide is complicated due to the inevitable electrochemical reconstruction. Herein, ZnS nanoparticles with Zn defect are anchored onto the surface of NiCo2S4 nanosheet to construct NiCo2S4/ZnS hybrids, which exhibit outstanding oxygen evolution performance with an ultralow overpotential of 140 mV. The anchoring of defective ZnS nanoparticles inhibit the volume expansion of NiCo2S4 nanosheet during the cycling process. Density‐functional theory reveals that the build‐in interfacial potential and Zn defect can facilitate the thermodynamic formation of *O to *OOH, thus improve their intrinsic activity.
Preparation, characterization and antioxidant activity of acetylated garlic polysaccharide, and garlic polysaccharide‐Zn (II) complex
Authors: Chen Xin , Huang Gangliang 
Published: June 2021

AbstractGarlic polysaccharide (PS) was extracted from garlic by hot‐water extraction. Acetylated garlic polysaccharide (AcPS) and garlic polysaccharide‐zinc complex (ZnPS) were synthesized. The results of Fourier transform infrared spectroscopy and nuclear magnetic resonance spectroscopy analysis showed that the modifications were successful. The antioxidant activities of PS, AcPS, and ZnPS were further investigated in vitro, including scavenging superoxide anion and hydroxyl radicals, antilipid peroxidation capacity, and reducing power. The results showed that the scavenging abilities of AcPS and ZnPS on hydroxyl radical (The IC50 of PS, AcPS, and ZnPS were 2.86, 1.62 and, 1.49 mg/ml, respectively,) and superoxide anion radical (The scavenging rate of PS, AcPS, and ZnPS were 1.5% and 1.8%, and 2.3%, respectively, when concentration was at 1.0 mg/ml.) were stronger than that of PS, and the inhibitory effect of AcPS on lipid peroxidation was significantly stronger than that of PS (The IC50 of PS and AcPS were 1.05 and 0.53 mg/ml, respectively.). It indicated that the acetylation was a favorable way to enhance the antioxidant activity of garlic PS; ZnPS complex could be applied as potential candidate for antioxidant and Zn supplement.