bluuebunny/crossref_metadata_2025_split huggingface dataset:
High Energy Storage Capabilities of CaCu3Ti4O12 for Paper-Based Zinc-Air Battery
Authors: Bhardwaj Upasana , Sharma Aditi , Gupta Vinay , Kushwaha H.S 
Published: December 2021

Abstract
A new perovskite material, CaCu3Ti4O12 (CCTO), is proposed as an efficacious electrocatalyst for oxygen evolution/reduction reactions for the development of zinc-air batteries (ZAB). Synthesis of this material adopted an effective oxalate route, which led to the purity in the electrocatalyst composition. The CCTO material is a proven potential candidate for energy applications because of its high dielectric permittivity (ε) and occupies an improved ORR activity with better onset potential, current density, and stability. The CCTO perovskite was also evaluated for the zinc-air battery as an air electrode, corresponding to the high specific capacitance of 1165 mAh g-1 with the greater cyclic efficiency and minimum variations in both charge/discharge processes. The highest power density (Pmax) measured was 32 mW cm-2. The OCV (Open Circuit Potential) obtained was 1.44 V for the as-developed battery. Also, the CCTO based paper battery shows an excellent performance achieving a specific capacity of 947.79 mAh g-1. The obtained results promise CCTO as a potential and cheap electrocatalyst for application in energy applications.
Comparative analysis of mitochondrial genomes in different species reveals the evolution of G-quadruplexes
Authors: Sugiyama Hiroshi , Sahayasheela Vinodh , Yu Zutao , Pandian Ganesh 
Published: December 2021

Abstract
G-quadruplexes (G4s) are noncanonical structures that can form in the genomes of a range of organisms and are known to play various roles in cellular function. G4s can also form in mitochondrial DNA (mtDNA) because of their high guanine content, and these G4s may play roles in regulating gene expression, DNA replication, and genome stability. However, little is known regarding the evolution and dissemination of G4s in mitochondria. Here we analyzed the potential G4-forming sequences in mtDNA of 16 species from various families and demonstrated that the heavy strand of mtDNA of higher-order organisms contained higher levels of G4 regions than that of lower-order organisms. Analysis of the codons in the light strand revealed enrichment of guanine/cytosine-rich regions in higher eukaryotes and of adenine/thymidine-rich regions in lower-order organisms. Our study showed the diversity of G4s in species ranging from lower to higher orders. In particular, mammals such as humans, chimpanzees, and monkeys display a greater number of G4s than lower-order organisms. These potentially play a role in a range of cellular functions and assist in the evolution of higher organisms.
Outcome of Neurocritical Disorders, A Multicenter Study from Sudan
Authors: Ali Khalid Mohamed , Salih Mahmoud Hussien , AbuGabal Hiba Hassan , Omer Mohammed Eltahier Abdalla , Ahmed Ammar ElTahir , Ahmed Khabab Abbasher Hussien Mohamed 
Published: December 2021

Abstract
Background:Patients with neurocritical disorders that require admission to intensive care units (ICUs) constitute about 10–15% of critical care cases.Objectives:To study the outcome of neurocritical disorders in intensive care units.Methodology:This is a prospective observational study which was conducted in neurocritical patients who were admitted in four intensive care units of major hospitals in Khartoum state during the period from November 2020 to March 2021.Results:72 neurocritical patients were included in this study, 40(55.6%) were males and 32(44.4%) were females. 21 (29.2%) patients fully recovered, 35 (48.6%) partially recovered and 16 (22.2%) died. The mortality of the common neurocritical diseases were as follows: Stroke 30.4%, Encephalitis (8.3%), Status epilepticus (11.1%), Guillain-Barre syndrome (GBS) (16.7%) and Myasthenia gravis (MG) (25%).Conclusion:This study identified that near two third of the patients required mechanical ventilation. Delayed admission was observed due to causes distributed between the medical side and patient side. The majority of patients were discharged from ICU with partial recovery.
Mobility of Organotin Pesticides: Azocyclotin And Cyhexatin In Clayey And Sandy Soils From The Northern Paraná State - Brazil
Authors: Lima Andre A.A , Onishi Bruno S.D , Watanabe Lycio S. , Santos Maria J. 
Published: December 2021

Abstract
Azocyclotin and cyhexatin are pesticides commonly used in mite control. However, these organotin compounds are highly harmful to the aquatic ecosystem and supposedly mobile in the soil.
In addition to not existing defined rules of use, few studies have been carried out on organotins' behavior and environmental control. Liquid chromatography has been pointed out for the OTC quantitation because of gas chromatography's thermal stability and derivatization limitations.
Hence, a new high-performance liquid chromatography method with photodiode array detection (HPLC-PDA) was developed for quality assurance and quality control (QA/QC) and environmental performance assessment purposes.
Hysteresis index (\emph{HI}) and mobilization factor were determined from sorption/desorption in sandy and clayey soils to assess mobility and environmental risk.
Mobilization was observed for the two compounds by applying the dual-mode Freundlich-Langmuir model to the isotherms. Azocyclotin showed greater mobility, 23\% and 19\%, and \emph{HI} of $-$0.15 and 7.8$\times$10$^{-4}$ for clayey and sandy soil samples, respectively. Although cyhexatin was practically immobile for both soil samples, it can be mobilized as an azocyclotin metabolite, increasing the environmental impact and risk for agricultural uses.
Acceptability, Effect and Cost of Mobile-Health on Art Adherence and Assessment of Covid-19 Knowledge Among Youths: A Mixed Methods Sequential Study in Kiryandongo. A Study Protocol Youth Trial
Authors: Naggirinya Agnes Bwanika , Meya David B , Rujumba Joseph , Waiswa Peter , Parkes-Ratanshi Rosalind 
Published: December 2021

Abstract
Background: AIDS is the leading cause of death among young people in sub-Saharan Africa. Adherence to antiretroviral therapy is the principal determinant for achieving and sustaining viral suppression, which decreases progression to AIDS and reduces risk of mortality. Few studies have evaluated mHealth adherence tools among youths in resource-limited settings.We aim to evaluate whethermHealth tool improves ART adherence outcomes among youth receiving ART at a rural district in Western Uganda. The Corona virus disease outbreak was announced a Public Health Emergency of International concern on Jan 2020; and declared a global pandemic by World Health Organization on Mar, 2020.In rural areas, there is little data on knowledge and myths on COVID among youths.General objective:To assessacceptability, effect and cost of themHealth tool on ART adherence, knowledge and myths on COVID-19among youth initiating and on ART at KiryandongoDistrict.Methods: This is a mixed methodsequential exploratory study, with the qualitative study conducted first followed by a randomized control trial and healthcare cost evaluation.The qualitative study will assess barriers, enablers of adherence and acceptability of mHealth among youths receiving care at three health facilities inKiryandongo District.The randomized control trial of 206 youth initiatingARTto either Standard of Care or mHealth tool plus Standard of care to assesseffect of mHealth tool on ART adherence and retention in care. Through a basic cell phone, participants in the intervention arm will receive pill reminders, clinic appointment reminders, health voice messages and self-reported symptoms in addition to standard of care. Collection of data on knowledge and myths on COVID-19, HIV and sexual behavior. The health care evaluationnested within randomized trial, will assess the cost of interventionin comparison to Standard of care.Discussion: This project will determine acceptability, effectiveness of mHealth, knowledge & myths on COVID-19and cost of delivering pill and clinic appointment reminders, and voice messages to a population with suboptimal ART adherence in a resource-limited setting.Trial registration: Fully registered under clinicaltrials.gov by 20th Jan 2021. The study is ongoing. Recruitment started Aug 2020.Clinical Trial registration: NCT 04718974
Educational Intervention on Social Media To Prevent Occupational Neck Pain; A Protocol for a Randomized Trial To Prevention Occupational Neck Pain in Teachers Profession
Authors: Tavafian Sedigheh Sadat , Moradi Zohre , Kazemi Seyedeh Somayeh 
Published: December 2021

Abstract
Background: Neck pain is one of the most common work-related musculoskeletal disorders (WMSDs). Which has important social and economic consequences such as reduced productivity due to absenteeism, leave and early retirement and financial losses due to medical expenses for the workforce, especially teachers, and is a serious problem among teachers. This study aims was to evaluate whether a theory-based intervention social media could change the high-risk behaviors that cause to job-related neck pain among teachers.Methods: This is a community-randomized controlled trial that will be done in three steps. The stages of the study include: The first stage is a qualitative study to obtain the items and areas of the researcher-made questionnaire based on the health belief model (HBM), the second stage is the psychometric evaluation of the questionnaire and the third stage is the design and implementation of model-based educational intervention in social media. The study population is middle school teachers in the 19th district of Tehran, which are randomly divided into two groups of intervention and control. The intervention group receives training packages on social media and the control group does not receive any training. The intervention tries to improve the knowledge, attitude, skills and self-efficacy in adopting neck pain prevention behaviors among teachers. The study will also assess whether the intervention can reduce disability caused by neck pain among teachers.Discussion: Job-related neck pain can have a negative impact on teachers' health. This study is an attempt to investigate the impact, development and implementation of interventions in reducing job-related neck pain on social media.Trial registration number: IRCT20210301050542N1Registered on 16 March 2021 in IRCT (Iranian registry of Clinical TrialEthics Code: IR.MODARES.REC.1399.163
Groundwater contamination by salinity, microoorganisms and nitrogen compounds in Zahedan city, southeastern Iran
Authors: Allahdadi Alieh , Jahanshahi Reza 
Published: December 2021

Abstract
Generally, the quality and availability of groundwater resources can be affected by urbanization. In this research, various impacts of urbanization on the height of the water table and quality of groundwater in an urban aquifer has been investigated for Zahedan city, Iran. The investigations indicated that the widespread use of wastewater discharge wells in the city area had increased the elevation of the water table by 2 to 6 meters and had reduced the salinity of shallow groundwater. The effluent in the city's sewage channel with high EC had no effect on the groundwater quality in the city due to the fact that the channel was cement-lined within the city area. Microbial surveys showed that elevated total coliforms were present in groundwater throughout the city area while fecal coliforms were only present at a limited number of sampling sites. In the central areas of the city, where the groundwater abstraction takes place at high rates from deep wells, the pollution was less. The wastewaters had high level of total coliform and fecal coliform contamination due to the discharge of domestic wastewater through wells and the dumping of solids wastes. The urban water supply network and water treatment plants samples were free of any microbial contamination. Finally, nitrate concentrations in the groundwater were high (27-392 mg/L) and in the wastewater were much higher (up to 600 mg/L).
An Integrated Framework of GRU Based on Improved Whale Optimization Algorithm for Flood Prediction
Authors: Ji Chunlei , Peng Tian , Zhang Chu , Hua Lei , Sun Wei 
Published: December 2021

Abstract
Accurate prediction of floods is the first step in formulating flood control strategies and reducing flood disasters. This research proposes a deep learning model based on Gate Recurrent Unit (GRU), Random Forest Algorithm (RF), Whale Optimization Algorithm (WOA) and Optimal Variational Mode Decomposition (OVMD) for flood prediction. First, the random historical time series is decomposed using OVMD. Secondly, combined with the RF feature importance measurement, select features with high importance to obtain the optimal input set. Third, use the GRU model to predict all sub-models, and use the WOA algorithm to optimize the hyperparameters in the GRU model. This study also proposes a hybrid strategy to improve the traditional WOA algorithm and enhance the optimization ability of the WOA algorithm. Finally, the prediction results of all sub-modes were aggregated to generate the final prediction result. The model was validated using data from three hydrological stations in the upper, middle and lower reaches of the Minjiang river basin in China. Through the results of the experiment, it can be seen that the proposed prediction model can effectively predict the flood time series, and has better accuracy than other models.
Neurofeedback for Opioid Dependent Patients in an Outpatient Setting: A Pilot Feasibility Study
Authors: Rempala Helena A. , Barterian Justin A. 
Published: December 2021

Abstract
Background: Neurofeedback (NF) has been described as “probably efficacious” when used in conjunction with other interventions for substance use disorders, including the most recent studies in population of individuals with opioid use disorder. Despite these promising outcomes, the seriousness of the opioid epidemic, and the high rate of relapse even with the most effective medication-assisted maintenance treatments NF continues to be an under-researched treatment modality. This article explores factors that affected the feasibility of adding Alpha/Theta Neurofeedback to treatment as usual for opioid dependence in an outpatient urban treatment center. The study strived to replicate previous research completed in Iran that found benefits of NF for opioid dependence.Methods: Out of approximately two dozen patients eligible for Alpha/Theta NF, about 60% (n=15) agreed to participate; however, only 2 participants completed treatment. The rates of enrollment in response to active treatment were monitored. Results: The 4 factors affecting feasibility were: 1) the time commitment required of participants, 2) ineffectiveness of standard incentives to promote participation, 3) delayed effects of training, and 4) the length and number of treatments required.Conclusion: The findings indicate a large scale study examining the use of NF for the treatment of opioid use disorder in the United States will likely be difficult to accomplish without modification to the traditional randomized control study approach and suggests challenges to the implementation of this treatment in an outpatient setting.
Simulation of a Ridge-Type Semiconductor Laser with Transversal Diffraction Gratings
Authors: Hirose Tatsuhiro , Numai Takahiro 
Published: December 2021

Abstract
This paper reports on improvement of stability of the fundamental horizontal transverse mode in a ridge-type semiconductor laser by incorporating transversal diffraction gratings. Kinks do not appear in current versus light-output curves by appropriately designing the number of the grating periods when the mesa width is 5 μm in which kinks exist in current versus light-output curves for conventional ridge-type semiconductor lasers.
New Mineral Names: Diamonds, Dumps, and Fumaroles
Authors: Celestian Aaron J. 
Published: December 2021

Abstract

In this issue
In this series of New Mineral Names, a thematic approach is used to help provide context for advances and discoveries in mineralogy. Planet Earth is ever-changing, and unique crystals are found in the tiniest of micro-geologic niches. With emerging analytical techniques, the formerly inaccessible becomes accessible. New minerals inspire creative approaches to overcoming chemical and technological challenges and can reveal what the Earth was like billions of years ago. In this issue, we look at recently described minerals that are associated with diamonds, dumps, and fumaroles: crowningshieldite, goldschmidtite, breyite, cardite, grimmite, hrabákite, freitalite, dioskouriite, dobrovolskyite, ferroefremovite, and vasilseverginite.
The influence of sensor installation angle on explosive shock wave overpressure test
Authors: Wang Liangquan , Kong Deren 
Published: December 2021

In the engineering measurement of explosion shock wave pressure, the installation method of shock wave pressure sensor is of great significance to accurately obtain shock wave pressure. Based on the actual shooting range explosion shock wave overpressure test program, this paper uses AUTODYN to establish a finite element numerical simulation model. The distance from the ground reflection pressure sensor to the explosion center is 3 m, 4 m, 5 m, and 6 m. The shock wave overpressure data in the range of 8° and 10° are acquired and analyzed. The analysis results show that the shock wave overpressure obtained when the sensor installation angle is absolute zero is the ideal value. When the sensor installation plate is within a certain range, the overpressure value of the explosion shock wave increases with the increase of the installation angle of the plate, and the installation angle of the sensor is positively correlated with the overpressure of the explosion shock wave.
O USO DE PROTOCOLOS NA GESTÃO DO CUIDADO DA HIPERTENSÃO ARTERIAL NA ATENÇÃO PRIMÁRIA À SAÚDE: UMA REVISÃO INTEGRATIVA
Authors: Dantas Rosimery Cruz de Oliveira , Dantas Davidson Cruz de Oliveira , Lima Valdênia Veríssimo , Silva João Paulo Teixeira , Amador Ana Edimilda , Azevedo Ulicélia Nascimento , Lopes Monique da Silva , Roncalli Angelo Giuseppe 
Published: December 2021

O uso de protocolos, na assistência a hipertensão arterial sistêmica (HAS), permite um melhor direcionamento nas condutas profissionais. Objetivou-se identificar na literatura nacional e internacional, a existência de protocolos para otimizar a gestão do cuidar ao cliente com HAS assistido na Atenção Primária à Saúde. Trata-se de uma revisão integrativa (dezembro/2016 a janeiro/2017). Bases: Scopus, Lilacs, Medline, Scielo, PubMed e Biblioteca Cochrane. A análise da pertinência dos estudos deu-se com a escala de Likert e índice de concordância, a textual com agregação dos objetivos e resultados em categorias. Likert > 4 classificou os estudos em muito pertinente. O índice de concordância foi > 88%. Foram incluídos 10 estudos e todos mostraram a importância do uso de protocolos como estratégia para o acompanhamento e controle da HAS. As categorias encontradas foram: avaliação, adesão e satisfação. Apesar da baixa adesão aos protocolos, a sua utilização é uma ferramenta importante no controle da HAS, e para um cuidar integral, é necessário um protocolo voltado para a equipe multiprofissional, que conte com a adesão de gestores, profissionais e clientes, reforçando a integralidade do cuidar.
Application Progress of Gd-EOB-DTPA-Enhanced MRI T1 Mapping in Hepatic Diffuse Diseases
Authors: Xu Long , Wen Xing , Feng Xu , Kang Yao 
Published: December 2021

Background:
In recent years, T1 mapping imaging based on Gd-EOB-DTPA-enhanced
magnetic resonance imaging (MRI) has resulted in new research and clinical applications in hepatic
diseases.

Objective:
The objective of the study is to analyze, prospect, and summarize the Gd-EOB-DTPA-
enhanced MRI T1 mapping technology in hepatic diseases in recent years.

Main Findings:
Gd-EOB-DTPA-enhanced T1 mapping has been used more frequently in liver diseases
regardless of 1.5T or 3.0T MRI equipment. Volume interpolated body examination (VIBE)
mapping sequence seems to be the recommended MRI scan sequence. In the evaluation of T1 value
on liver function, the hepatobiliary phase 10 minutes after enhancement is the recommended
time point. The fat fraction and hepatic steatosis grade based on MRI-derived biomarkers are easier
to implement and popularize than a liver biopsy. Gd-EOB-DTPA-enhanced MRI T1 mapping can
not only be used to evaluate the degree of liver injury, the stage of liver fibrosis, and the liver reserve
function of patients with liver cirrhosis but also to distinguish focal liver lesions and predict
the differentiation degree of hepatocellular carcinoma. At the same time, it has some value in predicting
tumor immunohistochemical indexes, such as Ki67, CD34.

Conclusion:
Gd-EOB-DTPA-enhanced MRI T1 mapping has great potential in the application of
diffuse and focal liver lesions. It is a quantitative study, trying to select homogeneous research objects
and try to use the same standards in scanning sequence and scanning time, especially for the
study of liver function, which is a focus of future research. The research on the relationship between
T1 value and tumor immunohistochemical indexes is worth consideration.
Effect of Edaravone on MicroRNA Expression in Exosomes after Hepatic Ischemia-reperfusion Injury
Authors: Fei Yanxia , Shao Jiali , Huang Ge , Wang Lijuan , Zou Shuangfa , Sun Huiping , Zheng Chumei , Yang Jinfeng 
Published: December 2021

Background and Objective:Hepatic ischemia-reperfusion injury (HIRI) results in serious complications after liver resection and transplantation. Edaravone (ED) has a protective effect on IRI. This study was designed to evaluate whether ED could protect the liver of rats from HIRI injury and explored its exosomal miRNA-related mechanism.Methods:The sham group, hepatic ischemia/reperfusion (IR group), and hepatic ischemia/reperfusion + edaravone (ED group) models were established. We determined the protective effect of ED by measuring alanine aminotransferase (ALT), aspartate aminotransferase (AST), malondialdehyde (MDA), superoxide dismutase (SOD); enzyme-linked immunosorbent assay for tumor necrosis factor- α (TNF-α) and interleukin-1β (IL-1β); hematoxylin-eosin staining and immunohistochemistry for histopathological changes. Exosomal miRNAs were subjected to second-generation sequencing to identify their differential expression. The results were analyzed using bioinformatics methods and validated using real-time quantitative polymerase chain reaction (RT-qPCR).Results:HIRI rats showed higher levels of ALT, AST, oxidative stress, and inflammatory markers; ED attenuated these effects. The sequencing results showed 6 upregulated and 13 downregulated miRNAs in the IR vs. sham groups, 10 upregulated and 10 downregulated miRNAs in the ED vs. IR groups. PC-3p-190-42101 was screened as an overlapping differentially expressed miRNA, and RT-qPCR validation showed that its expression in HIRI rats was significantly decreased; ED prevented this downregulation. Moreover, the expression of PC-3P-190-42101 was significantly correlated with the level of inflammatory factors.Conclusion:These findings indicate that ED can regulate the level of inflammatory factors by affecting the expression of miRNA PC-3p-190-42101 in plasma exosomes to protect the liver from IRI.
'Mucormycosis': A Fungal Infection Threatening India During COVID-19' - A Review
Authors: Ashique Sumel 
Published: December 2021

:During the second wave of Covid-19 in India, doctors recently reported a outbreak of cases involving a rare infection-called the “black fungus”-among recovering and recovered Covid-19 patients. The frequency of bacterial and fungal coinfections has been continuously rising. At the same time, invasive pulmonary aspergillosis is increasingly being recognized in association with nCOVID-19. Currently, India is suffering from a newly maiming disease associated with nCOVID-19 infected patients; at the time of the treatment, it can be developed into rhino-orbital mucormycosis. There are some approved antifungal therapies for treating this fungal infection. The background, risk factors, and associated reports about the infection are described in this review.