bluuebunny/crossref_metadata_2025_split huggingface dataset:
A highly efficient and green protocol for the synthesis of 3,3′-(arylmethylene)-bis(2-hydroxynaphthoquinone) derivatives catalyzed by a dicationic molten salt
Authors: Zare Abdolkarim , Ghobadpoor Aysoda 
Published: January 2021

Abstract
A highly efficient and green protocol for the synthesis of 3,3′-(arylmethylene)-bis(2-hydroxynaphthoquinone) {3,3′-(arylmethylene)-bis(2-hydroxynaphthalene-1,4-dione)} derivatives has been developed. The reaction of 2-hydroxynaphthoquinone (2-hydroxynaphthalene-1,4-dione) (2 eq.) and arylaldehydes (1 eq.) in the presence of the dicationic molten salt N,N,N′,N′-tetramethylethylenediaminium bis-hydrogensulfate ([TMEDAH2][HSO4]2) under solvent-free conditions afforded the mentioned compounds in high yields and relatively short reaction times.
The effect of temperature on the structural, dielectric and magnetic properties of cobalt ferrites synthesized via hydrothermal method
Authors: Majid Farzana , Shahin Ammarah , Ata Sadia , Bibi Ismat , Malik Abdul , Ali Adnan , Laref Amel , Iqbal Munawar , Nazir Arif 
Published: January 2021

Abstract
A series of cobalt ferrite nanoparticles were prepared using hydrothermal process by varying the reaction temperature. The structural, magnetic and dielectric properties have been studied with the help of X-ray diffractometer (XRD), vibrating sample magnetometer (VSM) and impedance analyzer respectively. XRD spectra of all samples confirmed the formation of cobalt ferrite (CoFe2O4) nanoparticles (NPs). The lattice constant ‘a’ for temperature series samples is averaged around 8.4023 Å. Crystallite size of temperature series is calculated by Debye–Scherer formula that lies in the range of 15.04–20.49 nm. Its values increase because the chance of coalescence increases by increasing temperature. The maximum packing factor is obtained for the sample with highest reaction temperature. From VSM data, we get the M–H hysteresis curves for complete temperature series which confirms the magnetic nature. The maximum saturation magnetization 150.67 emu/g is obtained for the sample prepared at highest temperature. Different magnetic parameter such as saturation magnetization, coercivity, retentivity, squareness ratio, anisotropy constant and magneton number has been calculated from VSM data. AC response of all prepared ferrites was studied with impedance analyzer of frequency range 20 Hz to 20 MHz. Ferrites are the insulating materials, so, eddy current does not induce in transformer cores made of ferrite materials. In the medical field cobalt ferrite is used for drug delivery, as a biosensor and in MRI.
Influence of Retrogression and Reaging Treatment on Intergranular Corrosion Resistance and Exfoliation Corrosion Resistance in AA7010 Aluminum Alloy
Authors: Krishnanunni S. , Ranganatha R. , Anil Kumar V. , Gupta R. K. , Ajithkumar G. 
Published: January 2021

Abstract
The aluminum alloys with zinc as the primary alloying element (AA7XXX series) exhibit high strength and are widely used as aircraft structural materials. These categories of aluminum alloys in their peak aging condition (T6) are known to be highly susceptible to general as well as stress corrosion cracking (SCC). Retrogression and reaging (RRA) treatment of this category of alloys leads to improvement in the corrosion resistance without significant compromise in strength. SCC was found to be improving in general in these alloys, but the intergranular corrosion (IGC) and exfoliation corrosion (EXCO) need to be evaluated. The effect of RRA heat treatment on the IGC and exfoliation of AA7010 aluminum alloy has been investigated and compared with T6 and T73 temper conditions of the alloy. The results indicate that the corrosion susceptibility of AA7010 aluminum alloy decreased by subjecting the alloy to multistage (RRA) heat treatment. It is attributed to the grain boundary precipitate coarsening and is also the major factor responsible for reducing the susceptibility to IGC and EXCO.
The clausal organization of Tuparí, an indigenous Brazilian language
Authors: Singerman Adam Roth 
Published: January 2021

AbstractThis paper provides a detailed description and analysis of the clausal organization of Tuparí, a Tupían language that is spoken by approximately 350 people in the Brazilian state of Rondônia. The paper focuses on several interrelated issues that have broader comparative and typological importance, including (a) the distribution of head-initial and head-final phrase structure, (b) the diverse surface realizations of the Tense Phrase, and (c) the distinction between true pronouns and pronoun-like agreement enclitics. Data are drawn from an in-progress corpus of native language texts, everyday conversations and elicited utterances. Differences between Tuparí and the other languages belonging to the Tupían family's Tuparían branch are highlighted at various points for comparative purposes.
The relationship between dysmenorrhea and sleep quality
Authors: CEYLAN POLAT Demet , MUCUK Salime 
Published: January 2021

Purpose: This study was conducted to determine the prevalence of dysmenorrhea and the relationship between dysmenorrhea and sleep quality.
Materials and Methods: This was a cross-sectional study. A total of 250 volunteer female university students, who met the inclusion criteria, participated in this study. To collect data a questionnaire form, the Visual Analog Scale (VAS) and Pittsburgh Sleep Quality Index (PSQI) were used.
Results: The prevalence of dysmenorrhea in students was 82.4%. Eighty-two percent of the students with dysmenorrhea had poor sleep quality. It was determined that 96.8% of the students with sleep division in the menstrual period and 96.3% of those with difficulty falling asleep had dysmenorrhea. In participants with dysmenorrhea, there were different level of correlation between poor sleep quality and the number of sleep divisions, severity of dysmenorrhea), and less duration of sleep.
Conclusion: Dysmenorrhea has a negative effect on sleep quality. In accordance with these results, it is advisable to identify students with dysmenorrhea and to give training on methods of coping with it to improve their sleep quality.
The pattern of sharp injuries and its associated factors among healthcare workers in Gambella town, Southwest Ethiopia
Authors: Mengistu Yitayeh B. , Desta Abebaw A. , Fekadu Sofonias A. 
Published: January 2021

<p class="abstract"><strong>Background:</strong> The objective of the study was to assess the pattern of needle stick and sharp injuries and associated factors among healthcare workers in Gambella Town, Southwest Ethiopia.</p><p class="abstract"><strong>Methods:</strong> Institutional-based cross-sectional study was conducted from 05 March to 20 April 2019. A total of 368 healthcare workers were recruited using a systematic random sampling procedure. The data were entered into Epi info 7 and exported to statistical package for the social sciences (SPSS) version 21 for analysis. P≤0.20 was used to select variables from bivariable logistic analysis to multivariable logistic analysis. P value of ≤0.05 with 95% confidence level was used to identify variables that were associated with needle stick and sharp injuries. </p><p class="abstract"><strong>Results:</strong> The prevalence of needle stick and sharp injuries among healthcare workers in Gambella town was 113 (32.2%) 95% CI (27.43, 36.97) with mean age of 30.35±7.73. Work experience &gt;10 years [AOR=2.24, 95% CI: (1.13, 4.43)], absence of training on occupational health and safety [AOR=4.89, 95% CI: (2.21, 10.84)], working more than 48 hours/week [AOR=3.44, 95% CI: (1.76, 6.74)], dissatisfaction with their work [AOR=3.76, 95% CI: (2.12, 6.69)], having low risk perception [AOR=5.82, 95% CI: (2.59, 13.07)], and having moderate risk perception [AOR=3.44, 95% CI: (1.83, 6.49)] were significantly associated with needle stick and sharp injuries.</p><p class="abstract"><strong>Conclusions:</strong> There was high prevalence of needle stick and sharp injuries among healthcare workers in Gambella town. Lack of training, low-risk perception, dissatisfaction with the working environment, long working hours, and long working experience were associated with needle stick and sharp injuries.</p>
Evaluation of restricted antibiotic utilization and cost-minimization analysis in a tertiary care hospital in India
Authors: Krishna Kumar Dhakchinamoorthi , Swapna Mani , Kanmani Srinivasan , Varsha Varghese , Vidya Nair V. 
Published: January 2021

<p class="abstract"><strong>Background:</strong> Antibiotic resistance is a major menace to public health and treatment of several infectious diseases, also associated with an economic burden to society. Pharmacoeconomic analysis of antibiotic usage and cost-minimization analysis provides better and low-cost drug selection for the patients.</p><p class="abstract"><strong>Methods:</strong> The study was conducted as a cross-sectional, observational analysis of restricted antibiotics in the prescriptions (n= 191). Cost minimization analysis was conducted for the restricted antibiotics alone. The drug costs of prescribed brands were compared with the least cost brands, and the percentage cost difference was calculated and compared by student paired ‘t’ test. P&lt;0.05 considered statistical significance. </p><p class="abstract"><strong>Results:</strong> The average age of the patients was found to be 58.1±18.3 (Mean±SD) years, and most of the restricted antibiotics were prescribed for the treatment of hospital-acquired infections 71.7%. Meropenem was prescribed highly 29.8% followed by imipenem (28.8%) and colistin (12%). The major reason for starting restricted antibiotics was found to be infectious diseases (27.7%). The cost-minimization analysis showed that the total unit cost for caspofungin (₹1,85,000 or $2523.40) was found to be higher followed by meropenem (₹1,29,800) in the prescriptions. The mean cost of actually prescribed restricted antibiotics was found to be ₹68,338±61,332 (Mean±SD). The lowest mean cost of restricted antibiotics was found to be ₹32,223±31,082 (p&lt;0.05).</p><p class="abstract"><strong>Conclusions:</strong> Pharmacoeconomic cost-minimization analysis was a useful tool for clinical pharmacist in the selection of appropriate antibiotics and minimizing the burden of the cost of the drugs, it provides a better outcome in patients while using restricted antibiotics with infectious disease.</p>
BYOD and its Application in the Healthcare Environment
Authors: Shabazi Masoomeh , Amini Rarani Mostafa , Tahmasebian Sharam , Jahanbakhsh Maryam 
Published: January 2021

In recent years, the number of people who use mobile devices for business and organizational purposes has increased. This phenomenon is now known as “bring your own device” (BYOD), and it is rapidly entering the health industry, which makes clear the necessity of studying its various dimensions for its implementation and application. Recently, the use of mobile devices is increasing due to the social tendencies of people. Rapid changes in modern gadgets and smartphones have also encouraged organizations to use their mobile devices in the workplace for business purposes, creating related opportunities and challenges. These cases have made the expansion of BYOD inevitable so that the only way to control BYOD’s threats is to accept its process and finally formulate related strategies and policies before using it.
Effect of Phospho Enriched Compost and Zinc on Productivity and Nutrient Uptake of Blackgram (Vigna mungo L.) in Sub-humid Southern Hills and Aravalli Region of Rajasthan
Authors: Meena Manisha , Jat Gajanand , Meena R.H. , Choudhary Roshan , Jain Devendra , Doodhwal Kiran , Jat Hemraj , Yadav Sharvan Kumar 
Published: January 2021

Background: Phosphorus (P) and zinc (Zn) are essential plant nutrients and their deficiency in soils has the adverse effect on the crop productivity, moreover the antagonistic effect of P on Zn is also important study aspect. Hence, the present investigation was carried out to study the effect of phospho enriched compost and zinc on productivity, nutrient content and uptake of Blackgram (Vigna mungo L.) in Sub-humid Southern Hills and Aravalli region of Rajasthan. Methods: The experiment was undertaken during Kharif 2018 at Rajasthan College of agriculture, Udaipur (Rajasthan). The treatments comprised of four levels of phospho enriched compost (PEC) i.e. control, PEC @ 2.0, 4.0 and 6.0 t ha-1 and four levels of zinc i.e. control, Zn @ 2.0, 4.0 and 6.0 kg ha-1. The experiment was laid out in a factorial randomized block design with three replications. Result: The increasing levels of phospho enriched compost and zinc upto 4 t ha-1 and 4 kg ha-1, respectively increased significantly (P=0.05) the number of nodules per plant, number of pods per plant, number of seeds per pod, test weight, seed yield, stover yield, nutrient content (N, K and Zn) and uptake (N, P, K and Zn) in seed and stover of blackgram. Whereas, the application of zinc significantly decreased the phosphorus content in seed and stover as compared to control. However, the combined application of phospho enriched compost @ 6 t ha-1 along with zinc @ 6 kg ha-1 was found to record higher seed and stover yield. The application of phospho enriched compost @ 4 t ha-1 and zinc @ 4 kg ha-1 along with the recommended dose of fertilizer results in significantly higher productivity, nutrient content and uptake of blackgram under Typic Haplustepts soil.
Peningkatan pengetahuan dan pemeriksaan skabies santri Pondok Pesantren Nurul Islam Sekarbela
Authors: Hidayat Lalu Husnul , Aini Siti Rahmatul , Hidajat Dedianto , Pratama Iman Surya 
Published: January 2021

[Bahasa]: Angka prevalensi skabies di pondok pesantren di Indonesia adalah sebesar 3,9-6% termasuk di Provinsi Nusa Tenggara Barat. Alih pengetahuan oleh tenaga kesehatan terdidik pada santri diperlukan untuk mencapai pesantren bebas skabies. Program pengabdian kepada masyarakat (PKM) ini bertujuan untuk menentukan peningkatan pengetahuan, status perilaku kebersihan santri dan kesehatan kulit santri melalui penyuluhan dan pemeriksaan skabies pada santri Madrasah Aliyah Nurul Islam Sekarbela, Kota Mataram. Peningkatan pengetahuan ditentukan melalui pemberian kuesioner pretest dan posttest setelah penyuluhan. Status perilaku kebersihan santri ditentukan melalui wawancara semi terstruktur. Status dermatologis ditentukan melalui penemuan lesi skabies dengan pemeriksaan fisik dan teknik dermoskopi. Penyuluhan yang telah dilakukan meningkatkan pengetahuan santri terkait skabies sebesar 25-90%. Status perilaku kebersihan santri terkait skabies pada aspek kebersihan diri terkait penularan masih rendah dengan persentase lebih dari 50%. Berdasarkan pemeriksaan fisik, sebesar 21% santri terinfeksi skabies (n = 52 orang) dengan status dermatologikus berupa papula, erilematosa, skuama, dan erosi.
Kata Kunci: alih pengetahuan, skabies, santri, madarasah
[English]: The prevalence of scabies in Islamic boarding schools in Indonesia is 3,9-6%, including the province of West Nusa Tenggara. A knowledge transfer by educated health workers to madrasa students (santri) is needed to protect boarding schools from scabies. This community service program aimed to elevate the students’ knowledge of scabies, develop their hygiene behavior, and help them understand skin protection. It was done through counseling and physical examinations on students of MA Nurul Islam Sekarbela. The increase of knowledge was examined through the provision of pre and post counseling questionnaires. The personal hygiene status was determined through semi-structured interviews. Meanwhile, dermatological status was assessed through the scabies lesions by the physical examination and dermoscopy techniques. The counseling increased students’ knowledge of scabies at 72%-95%. The aspect of personal hygiene relating to transmissions is still low (> 50%). Based on the physical examinations, 21% of the students were infected with scabies (n = 52) in the form of papules, erythematous, squama, and erosion.
Keywords: knowledge transfer, scabies, santri, madrasa
Prognostic Value of Atherosclerotic Extent in Diabetic Patients with Non-Obstructive Coronary Artery Disease
Authors: Ding Yipu , Liu Zinuan , Dou Guanhua , Yang Xia , Wang Xi , Shan Dongkai , He Bai , Jing Jing , Chen Yundai , Yang Junjie 
Published: January 2021

Abstract
Background and Objective: Atherosclerotic extent was approved to be associated with adverse cardiac events. Risk score derived by coronary computed tomography angiography (CCTA) could identify high-risk group among patients with non-obstructive coronary artery disease (CAD) but its ability is still uncertain in the presence of diabetes mellitus (DM). The purpose of this study was to investigate the prognostic value of the plaque burden shown by CCTA in diabetic patients with non-obstructive CAD.Methods and Results: 813 DM patients (age 58.9±9.9 years, 48.1% male) referred for CCTA due to suspect CAD in 2015-2017 were consecutively included. During a median follow-up of 31.77 months, 50 MACEs (6.15%) were experienced, including 2 cardiovascular deaths, 14 non-fatal myocardial infarction, 27 unstable angina requiring hospitalization and 7 strokes. 3 groups were defined based on coronary stenosis combined with Leidon score, as normal, non-obstructive Leidon<5, and non-obstructive Leidon≥5. Cox models was used to assess the prognosis of plaque burden within these groups. An incremental incidence of outcome event rates was observed. After adjustment for age, gender, and presence of high-risk plaque, the group of Leidon≥5 showed a higher risk than Leidon<5 in non-obstructive CAD (HR:1.88 95%CI:1.03-3.42, p＝0.039). Similar results were illustrated when segment involvement score was used for sensitivity analysis.Conclusion: Atherosclerotic extent was associated with the prognosis of DM patients with non-obstructive coronary disease, highlighting the importance of better risk stratification and management.
Efficacy of Doxycycline in treating COVID-19 Positive Patients: A Case Series
Authors: Meybody Zohreh Akhoundi , Owlia Mohammad Bagher , Owlia Sina , Mousavinasab Seyed Rohollah 
Published: January 2021

Abstract
Background: Given the high morbidity and mortality caused by Coronavirus Disease 2019 (COVID-19), scientific research is necessary to achieve a proper treatment regimen. Since doxycycline is effective in reducing inflammatory factors, including IL-6 and TNF-alpha that play an important role in initiating cytokine storms and probably causing death in patients with COVID-19, its use is associated with low side effects and can be used orally, the present study was attempted to evaluate the efficacy of doxycycline in the treatment of inpatients and outpatients with COVID-19.Methods: This descriptive and prospective study was performed on inpatients and outpatients were diagnosed with COVID-19 based on polymerase chain reaction (PCR) test from nasopharyngeal secretions or computerized tomography scan (CT Scan). Patients who met the inclusion criteria received doxycycline at a dose of 100 mg every 12 hours for 7 days and then were evaluated on the baseline day and on days 3, 7, and 14 after admission for cough, Shortness of breath, temperature and oxygen saturation.Results: Out of 21 patients, 11 patients were male and 10 patients were female. Cough, SOB, temperature, and O2 sat improved in both of outpatients and inpatients compared to baseline. In general, the results showed that doxycycline was more effective in improving cough, SOB, temperature, and O2 sat in outpatients than inpatients. Conclusion: It can be concluded that doxycycline with the dose and duration prescribed in our study could play an effective role in the treatment of patients with COVID-19.
Association between Liver Enzymes and Dyslipidemia in Yemeni Patients with Type Two Diabetes Mellitus
Authors: Dahman Lotfi S. Bin , Humam Mariam A. , Barahman Omer M. 
Published: January 2021

Abstract
Type two diabetes mellitus (T2DM) is characterized by chronic hyperglycemia and is associated with dyslipidemia and liver function disorders. This study was conducted to assess the association between liver enzymes and elevated lipid profile in a sample of Yemeni patients with T2DM. A case-control study comprising 142 T2D patients and 142 healthy control subjects was carried out at the outpatient clinics of Ibn-Sina hospital, Mukalla, during the period from January to May 2020. Serum fasting blood glucose (FBG), total cholesterol, triglyceride, high-density lipoprotein cholesterol (HDL-C), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyl transferase (GGT) were analyzed using the Cobas Integra Plus 400 autoanalyzer. Also, anthropometric and blood pressure measurements were taken from each participant. Independent sample T-test and Pearson correlation coefficient were used. T2D patients had significantly higher FBG (P= <0.0001), total cholesterol (P= <0.0001), LDL-C (P= <0.0001), and GGT (P= <0.0001) while, HDL-C was significantly lower in T2D patients (P= 0.021). In correlation analysis, serum GGT was positively associated with FBG (r= 0.216; P= <0.0001), total cholesterol (r= 0.196; P= 0.0001), triglyceride (r= 0.123; P= 0.038), and LDL-C (r= 0.209; P= <0.0001). Also, serum ALT was positively associated with FBG (r= 0.145, P= 0.014) and triglyceride (r= 0.172, P= 0.004). In conclusion, higher levels of ALT and GGT are used as the predictive biomarkers for NAFLD in T2D patients with hyperlipidemia. Thus, routine screening of liver enzymes and lipid profile in T2D patients is recommended for the early detection of liver abnormalities and diminish diabetes complications.
Morphological Physiological and Transcriptional Response to Low Nitrogen Stress in Populus Deltoides Marsh. Clones With Contrasting Nitrogen Use Efficiency
Authors: Chen Cun , Chu Yanguang , Huang Qinjun , Zhang Weixi , Ding Changjun , Zhang Jing , Li Bo , Zhang Tengqian , Li Zhenghong , Su Xiaohua 
Published: January 2021

Abstract
Background: Nitrogen (N) is one of the main factors limiting the wood yield in poplar cultivation. Understanding the molecular mechanism of N utilization could play a guiding role in improving the nitrogen use efficiency (NUE). Results: In this study, three N-efficient genotypes (A) and three N-inefficient genotypes (C) of Populus deltoides were cultured under low N stress (5 μM NH4NO3) and normal N supply (750 μM NH4NO3). The dry matter mass, leaf morphology, and chlorophyll content of both genotypes decreased under N starvation. Interestingly, N starvation induced fine root growth in A, but not in C. Next, a detailed time-course analysis of enzyme activities and gene expression in leaves identified 2,062 differentially expressed genes (DEGs) in A and 1,118 in C, most of which were up-regulated. Moreover, the sensitivity to N starvation of A was weak, and DEGs related to hormone signal transduction played an important role in the low N response in A. The weighted gene co-expression network analysis identified genes related to membrane, catalytic activity, enzymatic activity, and response to stresses might be critical for poplar’s adaption to N starvation and these genes participated in the negative regulation of various biological processes. Finally, ten inﬂuential hub genes and twelve transcription factors were identified in the response to N starvation, among them Podel.19G001200, Podel.19G035300, Podel.02G021400, and Podel.04G076900 were related to programmed cell death, and the defense response, and PodelWRKY41, PodelWRKY75, PodelWRKY18, PodelBHLH25, PodelBHLH30, PodelBHLH, and PodelHY5 were involved in plant signal transduction.Conclusions: Under the condition of N starvation, A showed stronger adaptability and a better NUE than C in morphology and physiology. The discovery of hub genes and TFs provided a new information for the analysis of the molecular mechanism of N efficient utilization and the improvement of NUE of poplar.