bluuebunny/crossref_metadata_2025_split huggingface dataset:
BI-RADS Reading of Non-Mass Lesions on DCE-MRI and Differential Diagnosis Performed by Radiomics and Deep Learning
Authors: Zhou Jiejie , Liu Yan-Lin , Zhang Yang , Chen Jeon-Hor , Combs Freddie J. , Parajuli Ritesh , Mehta Rita S. , Liu Huiru , Chen Zhongwei , Zhao Youfan , Pan Zhifang , Wang Meihao , Yu Risheng , Su Min-Ying 
Published: November 2021

BackgroundA wide variety of benign and malignant processes can manifest as non-mass enhancement (NME) in breast MRI. Compared to mass lesions, there are no distinct features that can be used for differential diagnosis. The purpose is to use the BI-RADS descriptors and models developed using radiomics and deep learning to distinguish benign from malignant NME lesions.Materials and MethodsA total of 150 patients with 104 malignant and 46 benign NME were analyzed. Three radiologists performed reading for morphological distribution and internal enhancement using the 5th BI-RADS lexicon. For each case, the 3D tumor mask was generated using Fuzzy-C-Means segmentation. Three DCE parametric maps related to wash-in, maximum, and wash-out were generated, and PyRadiomics was applied to extract features. The radiomics model was built using five machine learning algorithms. ResNet50 was implemented using three parametric maps as input. Approximately 70% of earlier cases were used for training, and 30% of later cases were held out for testing.ResultsThe diagnostic BI-RADS in the original MRI report showed that 104/104 malignant and 36/46 benign lesions had a BI-RADS score of 4A–5. For category reading, the kappa coefficient was 0.83 for morphological distribution (excellent) and 0.52 for internal enhancement (moderate). Segmental and Regional distribution were the most prominent for the malignant group, and focal distribution for the benign group. Eight radiomics features were selected by support vector machine (SVM). Among the five machine learning algorithms, SVM yielded the highest accuracy of 80.4% in training and 77.5% in testing datasets. ResNet50 had a better diagnostic performance, 91.5% in training and 83.3% in testing datasets.ConclusionDiagnosis of NME was challenging, and the BI-RADS scores and descriptors showed a substantial overlap. Radiomics and deep learning may provide a useful CAD tool to aid in diagnosis.
Pharmacokinetics and Monte Carlo Simulation of Meropenem in Critically Ill Adult Patients Receiving Extracorporeal Membrane Oxygenation
Authors: Lee Jae Ha , Lee Dong-Hwan , Kim Jin Soo , Jung Won-Beom , Heo Woon , Kim Yong Kyun , Kim Se Hun , No Tae-Hoon , Jo Kyeong Min , Ko Junghae , Lee Ho Young , Jun Kyung Ran , Choi Hye Sook , Jang Ji Hoon , Jang Hang-Jea 
Published: November 2021

Objectives: There have been few clinical studies of ECMO-related alterations of the PK of meropenem and conflicting results were reported. This study investigated the pharmacokinetics (PK) of meropenem in critically ill adult patients receiving extracorporeal membrane oxygenation (ECMO) and used Monte Carlo simulations to determine appropriate dosage regimens.Methods: After a single 0.5 or 1 g dose of meropenem, 7 blood samples were drawn. A population PK model was developed using nonlinear mixed-effects modeling. The probability of target attainment was evaluated using Monte Carlo simulation. The following treatment targets were evaluated: the cumulative percentage of time during which the free drug concentration exceeds the minimum inhibitory concentration of at least 40% (40% fT&gt;MIC), 100% fT&gt;MIC, and 100% fT&gt;4xMIC.Results: Meropenem PK were adequately described by a two-compartment model, in which creatinine clearance and ECMO flow rate were significant covariates of total clearance and central volume of distribution, respectively. The Monte Carlo simulation predicted appropriate meropenem dosage regimens. For a patient with a creatinine clearance of 50–130 ml/min, standard regimen of 1 g q8h by i. v. infusion over 0.5 h was optimal when a MIC was 4 mg/L and a target was 40% fT&gt;MIC. However, the standard regimen did not attain more aggressive target of 100% fT&gt;MIC or 100% fT&gt;4xMIC.Conclusion: The population PK model of meropenem for patients on ECMO was successfully developed with a two-compartment model. ECMO patients exhibit similar PK with patients without ECMO. If more aggressive targets than 40% fT&gt;MIC are adopted, dose increase may be needed.
Factors Associated With Hypertension Awareness, Treatment, and Control Among Adults in Kerala, India
Authors: Cao Yingting , Sathish Thirunavukkarasu , Haregu Tilahun , Wen Yu , Mello Gabrielli Thais de , Kapoor Nitin , Oldenburg Brian 
Published: November 2021

Background: Hypertension, the most significant risk factor for cardiovascular disease, is an increasing contributor to global health burden, particularly in low- and middle-income countries (LMICs) such as India. While the rates of hypertension awareness, treatment, and control in India have been reported in several studies, the factors associated with these rates are less well-understood. Existing studies are predominantly cross-sectional, and the factors examined are limited. Understanding the predictors associated with these rates, using more rigorous study designs, is crucial for the development of strategies to improve hypertension management.Aims: To examine a range of factors associated with hypertension awareness, treatment, and control using both cross-sectional and longitudinal analyses.Methods: Data was derived from a population-based sample of 1,710 participants from Kerala, aged 30–60 years. We examined a comprehensive range of factors, including demographic, behavioral factors, anthropometric, clinical measures, psychosocial factors and healthcare utilization. Multilevel mixed effects logistic regression was used for both cross-sectional and longitudinal analyses (repeated measures for all variables across 2 years) to determine the factors associated with awareness, treatment, and control of hypertension.Results: A total of 467 (27.3%) participants had hypertension at baseline. Among those, the rates of awareness, treatment, and control of hypertension were 54.4, 25.5, and 36.4%, respectively. Being male (OR 0.27, 95% CI 0.14–0.53) and consumption of alcohol (OR 0.49, 95% CI 0.31–0.80) were significant predictors of poorly controlled hypertension (longitudinal analysis). Depression (OR 2.04, 95% CI 1.15–3.61) and fair-to-poor self-perceived health status (OR 1.87, 95% CI 1.15–3.04) were associated with increased hypertension awareness, whereas anxiety (OR 1.97, 95% CI 1.04–3.71) was associated with increased hypertension treatment (cross-sectional analysis). Seeking outpatient service in the past 4 weeks was associated with higher awareness (OR 1.09, 95% CI 1.27–2.87), treatment (OR 1.73, 95% CI 1.20–2.50) and control (OR 1.96, 95% CI 1.37–2.80) (longitudinal analysis).Conclusion: Our findings suggest the importance of considering psychosocial factors and better engagement with health services in hypertension management, as well as giving more attention to body fat control and largely male-related behaviors such as alcohol consumption, taking into account of some Indian specific attributes.
Effects of Social Capital and Leisure Participation on Self-Rated Health of Urban Residents in Southwest China
Authors: Hu XiaoYan , Hu MingWen 
Published: November 2021

Background: Leisure provides opportunities for urban and rural residents to relax, recover their vitality, and improve their personal growth, development, and well-being. However, the impact of the leisure participation process, types, obstacles, participation motivation, and satisfaction on health is not very clear, especially the impact of leisure behavior on health, and is worthy of in-depth discussion.Objective: The objective of this study was to explore the impact of social capital and leisure participation on the self-rated health of urban residents in China so as to provide an important reference for national health promotion activities.Methods: the questionnaire on the relationship between social capital, leisure behavior, and self-rated health was compiled by ourselves. The residents participating in leisure and fitness in 25 residential fitness centers in Chengdu were investigated in the morning and evening, and the obtained data were processed by exploratory and confirmatory factor analysis.Results: (1) Social capital had no direct influence on leisure hindrance; leisure motivation and leisure participation had no direct influence on self-rated health. (2) Leisure satisfaction has a direct positive impact on self-rated health, while leisure hindrance has a significant negative impact on self-rated health. (3) Social capital has a direct positive impact on leisure satisfaction, and social capital has a direct positive impact on self-rated health. Leisure satisfaction plays an intermediary role in the path of social capital affecting self-rated health, and the intermediary force exceeds the direct impact of social capital on self-rated health.Conclusion: The effect of leisure satisfaction on self-rated health is higher than that of social capital, and it plays an intermediary role in the impact path of social capital on self-rated health. Therefore, how to make urban community residents with different backgrounds obtain leisure satisfaction through leisure activities is an important topic of national health promotion.
Submicron-Sized Vermiculite Assisted Oregano Oil for Controlled Release and Long-Term Bacterial Inhibition
Authors: Kothalawala Sukitha Geethma , Zhang Jun , Wang Yue , Yu Chengzhong 
Published: November 2021

Oregano essential oil (OEO) is a natural compound consisting of potent antibiotic molecules. Its volatility is the major obstacle against the transportation and anti-bacterial performance. In this work, submicron-sized vermiculite (SMV) particles were prepared from Australian vermiculite clay by ball milling, and tested as a potential particulate-carrier for OEO. The loading of OEO by SMV can be easily achieved by mechanical mixing. Compared to raw vermiculite and free OEO, the OEO-loaded SMV displayed sustained isothermal release behaviour of OEO and demonstrated enhanced antibacterial performance in in vitro antibacterial tests against Escherichia coli (E. coli) and Staphylococcus epidermidis (S. epidermidis). This study provides a facile and commercially viable approach in designing advantageous carriers for volatile actives in antimicrobial applications.
Perancangan Model Simulator dan Performansi Kesalahan Bit untuk Variasi Tipe Modulasi Digital Dalam Lingkungan Kanal Additive White Gaussian Noise (AWGN)
Authors: Taufiqurrahman Aditya 
Published: November 2021

Penelitian ini dibuat berdasarkan permasalahan pada penelitian sebelumnya, dimana belum menampilkan gelombang sinyal sesudah melewati kanal Additive White Gaussian Noise (AWGN), serta menampilkan hasil simulasi perbandingan kesalahan bit yang ditampilkan dalam bentuk grafik kurva untuk berbagai tipe modulasi. Selain itu gelombang sinyal probabilitas kesalahan bit masih ditampilkan terpisah serta belum melakukan analisa antara perhitungan dengan hasil simulasi. Maka pada penelitian ini akan dilakukan pengembangan pada source code dan juga dibuatnya graphical user interface (GUI) Matlab beserta dengan perhitungan teoritisnya. Pada hasil simulasi jumlah bit minimal sebesar 100 bit didapatkan untuk modulasi amplitude Shift Keying (ASK), untuk modulasi frekuency shift keying (FSK) dan untuk binary phase shift keying (BPSK). Sedangkan pada jumlah bit maksimum bit sebesar 500 bit didapatkan untuk modulasi ASK, untuk modulasi FSK, dan untuk modulasi BPSK. Dari dua data tersebut menunjukan bahwa data simulasi sudah sesuai dengan teori yang ada, dimana semakin besar energi bit yang digunakan maka bit error rate (BER) yang dihasilkan akan semakin kecil. Kesesuaian simulasi dengan teori didukung juga oleh hasil perhitungan probabilitas kesalahan bit. Hasil simulasi dan teoritis probabilitas kesalahan bit memiliki karakteristik yang sama, dimana modulasi BPSK memiliki penurunan probabilias kesalahan bit yang lebih kecil dibandingkan modulasi ASK dan FSK. Selain itu didapatkan bahwa hasil perhitungan mengalami penurunan kesalahan bit yang lebih kecil serta ideal pada Eb/N0 yang sama untuk setiap percobaannya.
Analisa Penggunaan Nilai Bobot Heuristik yang Berbeda pada Algoritma Weighted A*
Authors: Diana Ipan , Herdiana Budi 
Published: November 2021

Path planning merupakan urutan keadaan untuk memindahkan objek dari keadaan awal ke keadaan akhir, serta menghindari daerah yang tidak dapat dilalui. Objek disini dapat berupa robot, mobil otonom dan yang lainnya. Algoritma A* merupakan algoritma pencarian jalur yang menggunakan estimasi jarak dengan menggunakan pencarian jalur terdekat untuk mencapai tujuan. Weighted A* adalah algoritma yang digunakan untuk memecahkan masalah pencarian jalur dengan mengubah nilai bobot pada fungsi heuristiknya. Tujuan dari penelitian ini yaitu menganalisa perbandingan algoritma Weighted A* dengan algoritma A*, serta menganalisa pengaruh nilai bobot heuristik pada algoritma Weighted A*. Pengujian yang dilakukan yaitu menggunakan lingkungan maze, narrow, trap, clutter. Hasil yang didapat pada perbandingan algoritma Weighted A* dan A*, dari hasil pengujian diperoleh algoritma Weighted A* menghasilkan waktu pencarian yang lebih baik yaitu sebesar 0,33 detik, sedangkan algoritma A* menghasilkan waktu 1,40 detik. Tetapi algoritma A* dapat menghasilkan jalur yang lebih optimal yaitu 163,69 dibandingkan algoritma Weighted A* yang menghasilkan jalur sebesar 164,52. Dengan strategi yang lebih menekankan pemilihan node yang lebih dekat dengan node goal, maka Weighted A* dapat menghasilkan jalur dengan waktu komputasi yang lebih cepat. Sedangkan algoritma A* karena memilih node dengan nilai heuristik terkecil, maka dapat menghasilkan jalur yang lebih optimal. Weighted A* cocok di implementasikan pada sistem yang membutuhkan waktu pencarian jalur yang lebih singkat tapi tidak harus optimal. Algoritma A* cocok di implementasikan pada sistem yang membutuhkan jalur optimal walaupun waktu pencariannya tidak terlalu cepat
Sistem Otomatis Pembuatan Nutrisi Ideal untuk Tanaman Pakcoy Menggunakan kendali Logika Fuzzy
Authors: Malik Aditya , Hartono Rodi 
Published: November 2021

Pada dasarnya, khususnya di Indonesia rata-rata perkebunan hidroponik itu masih menggunakan sistem manual, termasuk dalam pengaturan nutrisi petani masih menggunakan sistem manual dalam pengaturannya. Hal tersebut memakan banyak waktu dalam melakukan pemberian nutrisi secara manual tersebut, petani harus telebih dahulu memberi air untuk setiap tandon nutrisi, lalu setelahnya petani harus memberi pupuk atau nutrisi A dan B untuk dicampur dengan air lalu diaduk. Tujuan dari penelitian ini adalah merancang dan mengimplementasikan sistem pengecekan dan pengaturan komposisi nutrisi dengan metoda logika fuzzy untuk mendapatkan dan menjaga kondisi ideal nutrisi untuk tanaman hidroponik jenis pakcoy. Dengan menggunakan metode fuzzy, sifat ketidakpastian yang sering muncul akan teratasi. Dengan membuat 19 himpunan keanggotaan input dan juga 19 himpunan keanggotaan output yang sudah dibuat dengan cara mengambil data untuk nilai konsentrasi nutrisi mencapai set point yaitu 1050-1400 ppm, sistem akan mampu membuat dan juga mempertahankan nilai konsentrasi nutrisi pada range ideal. Dari pengujian sistem yang dilakukan didapatkan kesimpulan berupa, penambahan nutrisi A dan B terbanyak yaitu 5100 mL dengan waktu 17 menit dalam keadaan wadah nutrisi maksimal, dan penambahan nutrisi A dan B paling sedikit adalah 300 mL dengan waktu 1 menit dalam keadaan wadah nutrisi maksimal.

Kata kunci : fuzzy, nilai konsentrasi, nutrisi, pakcoy, PPM
Pembelajaran Edutainment Dalam Penanaman Karakter Cinta Tanah Air Pada Anak Usia Dini di Sekolah Dasar
Authors: Yanuardianto Elga 
Published: November 2021

Konsep edutainment mencoba memadukan antara pendidikan dan hiburan, yang didalam konsep edutainment tersebut terdapat beberapa pendekatan yang lebih kita kenal sebagai SAVI (Somatik, Auditori, Visual dan Intelektual). Metode penelitian ini menggunakan jenis penelitian Library research, yaitu jenis penelitian yang dilakukan dan difokuskan pada penelaahan, pengkajian dan pembahasan literature-literatur, baik klasik maupun modern. Literature berbahsa arab, inggris, Indonesia dan sebagainya yang ada kaitannya dengan persoalan ini. Penelitian ini bersifat analisis deskriptif. Sumber data penelitian ini yaitu: Sumber primer dari pemikiran Beby De Poter. Sumber skunder meliputi: buku, artikel atau esai yang membahas konsep edutainment, dan buku yang berkenaan dengan konsep psikologi belajar anak, serta buku pendidikan karakter, terutama karakter cinta tanah air. Hasil penelitian ini menunjukkan: (1) Pembelajaran Edutainment Dalam Penanaman Karakter Cinta Tanah Air Bagi Anak Usia Dini Di Sekolah Dasar, yaitu: menumbuhkan karakter cinta tanah air, memunculkan emosi minat anak seperti rasa senang dan gembira dalam pembelajaran, guru dalam menyampaikan pembelajaran di kelas harus menunjukkan sikap kepedulian terhadap peserta didik. (2) Proses Penanaman Karakter Cinta Tanah Air Bagi Anak Usia Dini Di Sekolah Dasar, yaitu: proses pembelajaran interaksi antara siswa dan guru terbangun suasana menyenangkan, fleksibiltas guru dalam menyampaikan materi menyesuaikan dengan emosi peserta didik, hubungan keakraban dan persahabatan sebagaimana teman sendiri, dan guru memberikan kebabasan berexspresi kepada perserta didik pada saat proses pembelajaran.
InAs/GaAsSb in-plane ultrahigh-density quantum dot lasers
Authors: Tanaka Motoyuki , Banba Keichiro , Sogabe Tomah , Yamaguchi Koichi 
Published: November 2021

Abstract
InAs in-plane ultrahigh-density quantum dots (IP-UHD QDs) were grown on GaAsSb/GaAs(001) by molecular beam epitaxy and introduced into the active layer of a ridge-waveguide AlGaAs/GaAs laser. The IP-UHD QD density was 5 × 1011 cm−2. Despite having a short cavity length, no high-reflective coating on the cavity edge and a small number of stacked QD layers, stable laser operation up to 80 ℃ has been achieved. IP-UHD QD lasers without p-type doping exhibited a characteristic temperature of 77 K. IP-UHD QD lasers have the same low internal loss as conventional QD lasers. Improved uniformity in IP-UHD QDs promises the achievement of ultralow threshold current.
Pelatihan Pengkayaan Pakan Pada Kelompok Pembudidaya Udang Sistem Backyard Di Kabupaten Barru
Authors: Hamsah Hamsah , Anwar Asni , Murni Murni , Malik Abdul , Khaeriyah Andi , Ikbal Muhammad , Darmawati Darmawati 
Published: November 2021

AbstrakMasyarakat di wilayah pesisir Desa Madello Kecamatan Balusu Kabupaten Barru memanfaatkan pekarangan rumah sebagai tempat budidaya udang vaname skala pembenihan melalui sistem backyard. Kendala utama yang sering dialami oleh kelompok pembudidaya udang “Pantai Palie” Desa Madello adalah rendahnya kelulushidupan udang yang umumnya terjadi pada fase mysis ke fase pascalarva, sehingga perlu penerapan teknologi tepat guna untuk meningkatkan hasil panennya. Salah satu upaya yang dilakukan untuk menyikapi masalah tersebut adalah menerapkan penggunaan prebiotik mannanoligosakarida (Bio-MOS) pada pakan alami Artemia sp. sebagai pakan larva udang untuk meningkatkan nilai nutrisi pakan. Metode pelaksanaan kegiatan dilakukan dengan metode diskusi, koordinasi, penyuluhan, pelatihan dan pendampingan kepada mitra. Berdasarkan hasil kegiatan pengabdian kepada masyarakat, kelompok pembudidaya udang “Pantai Palie” menjadi mengetahui dan terampil melakukan pengkayaan pakan alami Artemia sp. dengan Bio-MOS, sehingga dapat meningkatkan kelulushidupan udang pada stadia mysis ke pascalarva. Saran yang diberikan dalam kegiatan ini adalah sebaiknya dilakukan pendampingan lanjutan terkait penggunaan Bio-MOS pada pakan Artemia sp. serta pelatihan manajemen usaha untuk meningkatkan kualitas sumberdaya manusia sebagai pengelola pada usaha pembenihan sistem backyard di Desa Madello,Kabupaten Barru.Kata Kunci: udang vaname, backyard, Artemia sp., mannanoligosakarida (Bio-MOS).AbstractCommunities in the coastal area of Madella Village, Balusu District, Barru Regency use their home yards as a place for cultivation vanname shrimp on a hatchery scale through the backyard system. The main obstacle that is often experienced by the "Palie Beach" shrimp farming group is the low survival rate of shrimp, which generally occurs from the mysis phase to the postlarva phase, so it is necessary to apply appropriate technology to increase crop yields. One of the efforts made to address this problem is to apply the use of prebiotic mannanoligosaccharides (Bio-MOS) in natural feed Artemia sp. as feed for shrimp larvae to increase the nutritional value of feed. The method of implementing the activities is carried out using the methods of discussion, coordination, counseling, training and mentoring to partners. Based on the results of community service activities, the "Palie Beach" shrimp farming group became aware of and skilled in enriching the natural feed of Artemia sp. with Bio-MOS, so that it can increase the survival of shrimp from the mysis stage to post-larvae. The advice given in this activity is that further assistance should be carried out regarding the use of MOS in Artemia sp feed as well as business management training to improve the quality of human resources as managers in a backyard hatchery business in Madello Village, Barru Regency.Key Word: vanname shrimp, backyard, Artemia sp., mannanoligosaccharides (Bio-MOS).
Edukasi Penanaman Bibit Vanili Pada Pekarangan Rumah di Desa Yehembang Kangin
Authors: Nugraha I Gusti Putu Riyan , Gama Adie Wahyudi Oktavia , Sutama Wayan 
Published: November 2021

AbstrakKegiatan pengabdian kepada masyarakat ini dilakukan dalam rangka memberikan edukasi penanaman bibit vanili pada pekarangan rumah di Desa Yehembang Kangin, Tabanan, Bali. Penulis menemukan bahwa masyarakat belum dengan baik memanfaatkan lahan kosong pada pekarangan rumah mereka. Tujuan dari pengabdian masyarakat ini adalah untuk membantu masyarakat dalam memanfaatkan lahan kosong pekarangan rumah mereka dengan menanam tanaman bibit vanili agar masyarakat memiliki kegiatan yang menghasilkan. Metode yang digunakan pada kegiatan ini adalah tahap observasi dan edukasi langsung dengan mengunjungi rumah warga yang memiliki pekarangan luas, maupun edukasi tidak langsung yang dilakukan secara online menggunakan media digital serta tahap evaluasi untuk mengetahui ketercapaian kegiatan. Dengan adanya kegiatan pengabdian ini, masyarakat akan lebih sadar akan keuntungan dalam memanfaatkan lahan pekarangan rumah serta membangun minat mereka dalam menanam bibit vanili.Kata Kunci: pemanfaatan pekarangan rumah, edukasi penanaman vanili, alternatif peningkatan kesejahteraan, pengabdian masyarakat AbstractThis community service activity was carried out in order to provide education on planting vanilla seeds in the yard of the house in Yehembang Kangin village, Tabanan, Bali. The author finds that the community has not properly utilized the vacant land in their yards. The purpose of this community service is to assist the community in utilizing the vacant land in their home yards by planting vanilla seeds so that the community has productive activities. The method used in this activity is the direct observation and education phase by visiting the homes of residents who have large yards, as well as indirect education conducted online using digital media and the evaluation phase to determine the achievement of the activity. With this service activity, the community will be more aware of the benefits of utilizing their yards and build their interest in planting vanilla seeds.Key Word: utilization of home yards, education on vanilla planting, alternatives for improving welfare, community services