bluuebunny/crossref_metadata_2025_split huggingface dataset:
Telemanagement of Home-Isolated COVID-19 Patients Using Oxygen Therapy With Noninvasive Positive Pressure Ventilation and Physical Therapy Techniques: Randomized Clinical Trial
Authors: Adly Aya Sedky , Adly Mahmoud Sedky , Adly Afnan Sedky 
Published: April 2021

Background
With the growing stress on hospitals caused by the COVID-19 pandemic, the need for home-based solutions has become a necessity to support these overwhelmed hospitals.

Objective
The goal of this study was to compare two nonpharmacological respiratory treatment methods for home-isolated COVID-19 patients using a newly developed telemanagement health care system.

Methods
In this single-blinded randomized clinical trial, 60 patients with stage 1 pneumonia caused by SARS-CoV-2 infection were treated. Group A (n=30) received oxygen therapy with bilevel positive airway pressure (BiPAP) ventilation, and Group B (n=30) received osteopathic manipulative respiratory and physical therapy techniques. Arterial blood gases of PaO2 and PaCO2, pH, vital signs (ie, temperature, respiratory rate, oxygen saturation, heart rate, and blood pressure), and chest computed tomography scans were used for follow-up and for assessment of the course and duration of recovery.

Results
Analysis of the results showed a significant difference between the two groups (P<.05), with Group A showing shorter recovery periods than Group B (mean 14.9, SD 1.7 days, and mean 23.9, SD 2.3 days, respectively). Significant differences were also observed between baseline and final readings in all of the outcome measures in both groups (P<.05). Regarding posttreatment satisfaction with our proposed telemanagement health care system, positive responses were given by most of the patients in both groups.

Conclusions
It was found that home-based oxygen therapy with BiPAP can be a more effective prophylactic treatment approach than osteopathic manipulative respiratory and physical therapy techniques, as it can impede exacerbation of early-stage COVID-19 pneumonia. Telemanagement health care systems are promising methods to help in the pandemic-related shortage of hospital beds, as they showed reasonable effectiveness and reliability in the monitoring and management of patients with early-stage COVID-19 pneumonia.

Trial Registration
ClinicalTrials.gov NCT04368923; https://clinicaltrials.gov/ct2/show/NCT04368923
Transforming a Patient Registry Into a Customized Data Set for the Advanced Statistical Analysis of Health Risk Factors and for Medication-Related Hospitalization Research: Retrospective Hospital Patient Registry Study
Authors: Taushanov Zhivko , Verloo Henk , Wernli Boris , Di Giovanni Saviana , von Gunten Armin , Pereira Filipa 
Published: April 2021

Background
Hospital patient registries provide substantial longitudinal data sets describing the clinical and medical health statuses of inpatients and their pharmacological prescriptions. Despite the multiple advantages of routinely collecting multidimensional longitudinal data, those data sets are rarely suitable for advanced statistical analysis and they require customization and synthesis.

Objective
The aim of this study was to describe the methods used to transform and synthesize a raw, multidimensional, hospital patient registry data set into an exploitable database for the further investigation of risk profiles and predictive and survival health outcomes among polymorbid, polymedicated, older inpatients in relation to their medicine prescriptions at hospital discharge.

Methods
A raw, multidimensional data set from a public hospital was extracted from the hospital registry in a CSV (.csv) file and imported into the R statistical package for cleaning, customization, and synthesis. Patients fulfilling the criteria for inclusion were home-dwelling, polymedicated, older adults with multiple chronic conditions aged ≥65 who became hospitalized. The patient data set covered 140 variables from 20,422 hospitalizations of polymedicated, home-dwelling older adults from 2015 to 2018. Each variable, according to type, was explored and computed to describe distributions, missing values, and associations. Different clustering methods, expert opinion, recoding, and missing-value techniques were used to customize and synthesize these multidimensional data sets.

Results
Sociodemographic data showed no missing values. Average age, hospital length of stay, and frequency of hospitalization were computed. Discharge details were recoded and summarized. Clinical data were cleaned up and best practices for managing missing values were applied. Seven clusters of medical diagnoses, surgical interventions, somatic, cognitive, and medicines data were extracted using empirical and statistical best practices, with each presenting the health status of the patients included in it as accurately as possible. Medical, comorbidity, and drug data were recoded and summarized.

Conclusions
A cleaner, better-structured data set was obtained, combining empirical and best-practice statistical approaches. The overall strategy delivered an exploitable, population-based database suitable for an advanced analysis of the descriptive, predictive, and survival statistics relating to polymedicated, home-dwelling older adults admitted as inpatients. More research is needed to develop best practices for customizing and synthesizing large, multidimensional, population-based registries.

International Registered Report Identifier (IRRID)
RR2-10.1136/bmjopen-2019-030030
Impact of Gamification on the Self-Efficacy and Motivation to Quit of Smokers: Observational Study of Two Gamified Smoking Cessation Mobile Apps
Authors: Rajani Nikita B , Mastellos Nikolaos , Filippidis Filippos T 
Published: April 2021

BackgroundThe proportion of smokers making quit attempts and the proportion of smokers successfully quitting have been decreasing over the past few years. Previous studies have shown that smokers with high self-efficacy and motivation to quit have an increased likelihood of quitting and staying quit. Consequently, further research on strategies that can improve the self-efficacy and motivation of smokers seeking to quit could lead to substantially higher cessation rates. Some studies have found that gamification can positively impact the cognitive components of behavioral change, including self-efficacy and motivation. However, the impact of gamification in the context of smoking cessation and mobile health has been sparsely investigated.ObjectiveThis study aims to examine the association between perceived usefulness, perceived ease of use, and frequency of use of gamification features embedded in smoking cessation apps on self-efficacy and motivation to quit smoking.MethodsParticipants were assigned to use 1 of the 2 mobile apps for a duration of 4 weeks. App-based questionnaires were provided to participants before app use and 2 weeks and 4 weeks after they started using the app. Gamification was quantitatively operationalized based on the Cugelman gamification framework and concepts from the technology acceptance model. The mean values of perceived frequency, ease of use, and usefulness of gamification features were calculated at midstudy and end-study. Two linear regression models were used to investigate the impact of gamification on self-efficacy and motivation to quit.ResultsA total of 116 participants completed the study. The mean self-efficacy increased from 37.38 (SD 13.3) to 42.47 (SD 11.5) points and motivation to quit increased from 5.94 (SD 1.4) to 6.32 (SD 1.7) points after app use. Goal setting was perceived to be the most useful gamification feature, whereas sharing was perceived to be the least useful. Participants self-reported that they used the progress dashboards the most often, whereas they used the sharing feature the least often. The average perceived frequency of gamification features was statistically significantly associated with change in self-efficacy (β=3.35; 95% CI 0.31-6.40) and change in motivation to quit (β=.54; 95% CI 0.15-0.94) between baseline and end-study.ConclusionsGamification embedded in mobile apps can have positive effects on self-efficacy and motivation to quit smoking. The findings of this study can provide important insights for tobacco control policy makers, mobile app developers, and smokers seeking to quit.
ANTIEMETIC ACTIVITIES OF INDONESIAN STINGLESS BEE PROPOLIS ON EMETIC INDUCED BY ANTI-TUBERCULOSIS DRUGS
Authors: MAHANI  , FATURACHMAN FIRMANSYAH , MICHELLE  , LEMBONG ELAZMANAWATI , SULAEMAN AHMAD , HARDINSYAH  , NURJANAH NUNUNG , SUNARNO  , SARIADJI KAMBANG 
Published: April 2021

Objective: This study aims to determine the antiemetic potential of stingless bee propolis in reducing the prevalence of nausea due to consumption of Anti-Tuberculosis Drugs (ATD) in Tuberculosis patients and to identify phytochemical compounds that act as an antiemetic in propolis.
Methods: The stingless bee propolis used was Wallacetrigona incisa from South Sulawesi. The clinical testing used the randomized controlled trial, randomization using permuted block randomization consisting of one positive control group and two treatment groups. The active components analyzed using Gas Chromatography-Mass Spectrometer (GC-MS) pyrolyzer.
Results: This study found that the measurement at week 0 obtained the mean value of nausea per week for each group P0 (Placebo), P1 (Propolis 6%), and P2 (Propolis 30%) were respectively 2.14; 1.5 and 5.2 events/week, at week 8 the prevalence of nausea by 2.0; 1.0; and 1.6 events/week, and week 24 the prevalence of nausea by 3.0; 0; and 0 events/week. There are 11 compounds with concentrations above 1% that act as antiemetic compounds either through direct and indirect mechanism with a total concentration reaches 75,47%.
Conclusion: Based on all determinant parameters, propolis of Wallacetrigona incisa species from South Sulawesi has antiemetic activity and can reduce the prevalence of emetic induced by ATD consumption in pulmonary TB patients.
PROXIMATE ANALYSIS AND AMINOACID PROFILES OF LEAVES, FLOWERS, PODS, AND SEEDS OF ERYTHRINA EDULIS FROM PERU
Authors: PARRAGA ADELMO , GONZALES JEVIER , PORTALES ROSARIO , RUIZ CANDY , ROJAS ROSARIO 
Published: April 2021

Objective: The study aim was to determine the proximate composition and amino acid profiles of seeds, leaves, pods, and flowers of Erythrina edulis that are consumed in Oxapampa, Perú.
Methods: Plant parts of E. edulis were analyzed for proximate composition (proteins, carbohydrates, fat, fiber, and ash) according to AOAC methods. Amino acid profiles were determined by HPLC analysis.
Results: Fat contents were low (<1.3%) in all four plant parts. The crude fiber was high in leaves and pods (19.9 and 15.1%, respectively). Protein contents in leaves (24.4%) and flowers (23.7%) were higher than that of the pods (19.3%). The limiting amino acids in the seeds were methionine and tryptophan, while the pods were deficient in four amino acids (methionine, tryptophan, histidine, and isoleucine). Of the four plant parts studied, the flowers turned out to be a promising source of protein because they meet most of the amino acid requirements for adults recommended by FAO.
Conclusion: The seeds and flowers of E. edulis have a high protein content and a good amino acid profile that makes them recommended for human consumption.
ANALISIS DAMPAK PENDAYAGUNAAN ZAKAT PRODUKTIF TERHADAP PENINGKATAN PENDAPATAN USAHA MUSTAHIK BERDASARKAN MODEL CIBEST (Studi Kasus pada Baitul Mal Aceh)
Authors: Jaili Muhibbul , Adnan Muhammad , Furqani Hafas 
Published: April 2021

Baitul Mal Aceh mendistribusikan zakat produktif menilai calon mustahik menggunakan model CIBEST yang bertujuan dapat memberi pengaruh yang signifikan terhadap keberhasilan usaha dan tingkat kemampuan mustahik dalam mengembangkan modal usaha yang telah diberikan oleh Baitul Mal. Penelitian ini berupaya menganalisis bagaimana penentuan calon mustahik dalam pendistribusian zakat produktif yang dilakukan oleh Baitul Mal Aceh dengan menggunakan model cibest, bagaimana dampak pemberdayaan zakat produktif terhadap peningkatan pendapatan usaha mustahik dengan menggunakan model CIBEST. Metode yang digunakan dalam penelitian ini adalah metode kualitatif dengan sumber data dari Baitul Mal Aceh. Teknik pengumpulan data dilakukan dengan cara observasi, wawancara, kuisioner dan dokumentasi. Hasil penelitian menunjukkan bahwa Penentuan calon mustahik dalam pendistribusian zakat produktif yang dilakukan oleh Baitul Mal Aceh berdasarkan model CIBEST. Tujuan penggunaan model CIBEST ini adalah untuk melihat tingkat kemiskinan dari calon mustahik, bukan hanya kemiskinan materiil saja yang dinilai tetapi juga kemiskinan spiritual. Dampak pemberdayaan zakat produktif terhadap peningkatan keberhasilan usaha mustahik pada Baitul Mal Aceh ketika dianalisis dengan menggunakan CIBEST terlihat adanya perubahan jumlah mustahik dari kategori miskin materil ke kategori sejahtera yang diketahui dari perubahan pendapatan usaha sebelum dan sesudah diberikan zakat produktif , hal ini sangat dipengaruhi oleh pengelolaan zakat produktif secara baik, pendistribusiannya tepat sasaran serta dilakukan pendampingan secara berlanjut.
UNIVERSIDADE E TRAJETÓRIAS PROFISSIONAIS: UMA LEITURA A PARTIR DAS RELAÇÕES DE GÊNERO
Authors: Cappellin Paola , Custodio Jorge 
Published: April 2021

O objeto deste artigo é refletir sobre o processo de aproximação a Universidade por parte de jovens trabalhadores no período entre 1999 e 2013. Período da realidade brasileira, marcada por frequentes crises econômicas que modificam em continuação o mercado de trabalho e, de consequência, fragilizam as trajetórias ocupacionais das pessoas. Estas alterações repercutem na vida das pessoas, introduzindo sentimentos de incerteza e de insegurança social. Neste contexto buscar o diploma universitário, é uma estratégia para ampliar as perspectivas futuras de promoção profissional. Os jovens trabalhadores ao retornar aos estudos, se disponibilizam a reorganizar seus cotidianos: conciliar o tempo dedicado a frequentar a universidade, a assistir a família e a manter o emprego. No decorrer do artigo, apesar de sublinhar as inovações, tudo indica que a cultura de gênero permanece como marcador de diferença de opções e escolhas.
Palavras-chave: gênero e trabalho; trabalho e universidade; gênero e universidade.
A FOGUEIRA QUE QUEIMOU A ALMA ONTEM INCINERA A EDUCAÇÃO HOJE: A PERSEGUIÇÃO AOS ESTUDOS DE GÊNERO
Authors: Montagnoli Renata Lewandowski , Vizzotto Liane 
Published: April 2021

O objetivo deste artigo é analisar as ações e os seus julgados no Supremo Tribunal Federal para apontar os pontos convergentes a favor dos estudos sobre gênero utilizados pelos ministros da Suprema Corte em suas decisões. A análise de oito Arguições de Descumprimento de Preceito Fundamental ou Ação Direta de Inconstitucionalidade, já julgadas pela Suprema Corte, constituem a base documental da pesquisa. A grosso modo, os achados mostram a legalidade dos estudos de gênero na escola, ancorada na Carta Constitucional.
Palavras-chave: Gênero; Legalidade; Supremo Tribunal Federal; Educação.
Importance of Pulse Pressure after Extracorporeal Cardiopulmonary Resuscitation
Authors: Lee Seok In , Lim Yong Su , Park Chul Hyun , Choi Woo Sung , Choi Chang Hyu 
Published: April 2021

Background: Recent reports have revealed better clinical outcomes
for extracorporeal cardiopulmonary resuscitation (ECPR) than
conventional cardiopulmonary resuscitation (CPR).
In this retrospective study, we attempted to identify predictors
associated with successful weaning off extracorporeal membrane
oxygenation (ECMO) support after ECPR.
Methods: The demographic and clinical data of 30 ECPR patients
aged over 18 years treated between August 2016 and January 2019 were
analyzed. All clinical data were retrospectively collected. The primary
endpoint was successful weaning from ECMO support after ECPR. Patients
were divided into two groups based on successful or unsuccessful weaning
off ECMO support (Weaned (n=14) vs. Failed (n=16)).
Results: Univariate logistic regression analysis showed that age,
CPR duration, ECMO complications, and loss of pulse pressure
significantly predicted the results of weaning off ECMO support.
However, multivariate logistic regression analysis showed that only CPR
duration and loss of pulse pressure independently predicted unsuccessful
weaning from ECMO support.
Conclusion: We conclude that long CPR duration and loss of pulse
pressure after ECPR predict unsuccessful weaning from ECMO. However,
unlike CPR duration, loss of pulse pressure during post-ECPR was related
to subsequent management. In patients with reduced pulse pressure after
ECPR, careful management is warranted because this reduction is closely
associated with unsuccessful weaning off ECMO support after ECPR.
Sustainable Urban Development And Ecological Externalities: Russian Case
Authors: Kudryavtseva Olga V. , Malikova Olga I. , Egorov Egor G. 
Published: April 2021

Inclusive, safe, resilient and sustainable cities are included in Sustainable development Goals. The choice between environmental and social well-being is a very acute issue. It is necessary to take into account the interaction of three city dimensions: economic, ecological and social. The aim of the paper is to evaluate externalities in terms of population for 114 Russian cities all over the country considering all three dimensions.The methods are the analysis of statistical data by econometric methods and their processing including geographical visualization. The data was taken from the Federal State Statistics Service database. The main results are the followings. The methodology for evaluation of externalities and estimation a hypothetical «efficient city size» in terms of population for Russian cities has been elaborated. The access to high-paying jobs and the availability of social benefits is often associated with living or moving to cities or regions with an unfavorable environment. Some cities feature an extremely high growth rate, dense population and often a low level of management and economic development.Then there was demonstrated how to achieve a hypothetical «efficient city size» by means of environmental management and changes in city area. This should be helpful in achieving the Sustainable Development Goals (especially the Goal 11) and some targets mentioned in the «New Urban Agenda». It is essential to pay attention to the function of a city and its spatial organization. Some other measures to rise efficiency were proposed as well.
Convergence of Biology and Gender Identity: A Study of Toni Morrison’s The Bluest Eyes
Authors: S.M. Dr. Vanamala 
Published: April 2021

The concept of gender and the related practices are born at the intersection of biology and politics. Biological markers; physical, physiological and psychological are politicized for hierarchical positioning of man and woman. The nexus between biology and politics has also generated the notion of ‘immutability’ of woman’s ‘gendered self’. Women too, having interiorized the inferiority of the self unquestioningly and have shown little inclination to redefine her-‘self’ after having accepted the nature’s role in her physical and physiological formation. The inability for better ‘self’ definition is also due to the failure to distinguish the exact point of confluence between biology and politics in the socially ascribed gender identities. Caught in the imbroglio woman has suffered crippled social and psychological consequences and the same is well substantiated in the novel The Bluest Eye by African American writer Toni Morrison. The women characters in the novel are paradigms of real life situations. While some do acutely suffer from social and psychological deprivation having interiorized the inferiority of their biological markers, others handle affirmatively the socially ascribed deprivations of their physical self by understanding the nexus between biology and cultural politics. The novel successfully explores the fact that distinct anatomical difference between man and woman or the biological identities of humans should not be the cause or source of discriminatory practices. Or in other words the novel denies the inferiority of woman as something hermetically sealed and that social factors; advantages of birth (like race and social class), socio-cultural pressures, cultivation of mental culture and many more are of great consequence for both the formation of ‘positive self- identity’ by woman and for challenging of gender significations.
ІДЕЇ ДИТИНОЦЕНТРИЧНОЇ ОСВІТИ В РЕФОРМАТОРСЬКІЙ ПЕДАГОГІЦІ НІМЕЧЧИНИ
Authors: Сторонська Оксана 
Published: April 2021

Статтю присвячено розгляду німецького педагогічного реформаторського руху кінця ХІХ – початку ХХ ст. Її безпосередньою метою є історико-педагогічний аналіз ідей дитиноцентричної освіти в реформаторській педагогіці Німеччини. У результаті досягнення мети розглянуто передумови виникнення і поширення ідей дитиноцентричної освіти в педагогічній теорії і шкільній практиці Німеччини у вказаний історичний період, висвітлено міркування відомих німецьких педагогів-реформаторів (Ф. Гансберга, Л. Гурліта, Г. Шаррельмана та ін.) щодо навчання і виховання молодого покоління на засадах дитиноцентризму, констатовано їх суголосність із сучасними освітніми тенденціями.
РАДЯНСЬКИЙ ЧИННИК У ЗБРОЙНІЙ БОРОТЬБІ НА ТЕРИТОРІЇ ДИСТРИКТУ “ГАЛИЧИНА” ГЕНЕРАЛЬНОГО ГУБЕРНАТОРСТВА (1941-1944)
Authors: ГУЛАЙ Василь , МАКСИМЕЦЬ Віра 
Published: April 2021

Анотація. Мета дослідження – аналіз провокативної ролі та диверсійно-розвідувального характеру дій радянських підпільників та партизан проти нацистського режиму та українського націоналістичного підпілля на території дистрикту “Галичина” Генерального Губернаторства. Методологія дослідження спирається на застосуванні комплексу історичних (проблемно-історичний, хронологічний, ретроспективний, синхроністичний), політологічних (порівняльний, структурно-функціональний, системного аналізу, нормативний), та загальнонаукових (аналітичний і синтетичний, індуктивний і дедуктивний) методів. Наукова новизна полягає у тому, що вперше в новітній українській історіографії зроблена спроба комплексного порівняльного аналізу розвідувально-дисерсійної діяльності груп радянських органів безпеки та військової розвідки на території дистрикту “Галичина” Генерального Губернаторства. Висновки. Отже, на підставі проведеного історичного дослідження можемо дійти до низки висновків, що при характеристиці воєнних дій на території Галичини, особливо від літа 1943 р., не варто залишати поза увагою існування та впливу розвідувально-диверсійних груп та окремих агентів органів державної безпеки СРСР й УРСР та Розвідувального управління Генерального штабу Червоної армії, радянського організованого підпілля та партизанських формувань. Виявлені архівні документи в сукупності з іншими критично опрацьованою історіографією дозволяють твердити про вагомий зовнішній чинник в організаційному оформленні прорадянського підпільницького та партизанського руху. При цьому, попри непоодинокі ефективні акції проти нацистської окупаційної адміністрації та Вермахту боротьба радянських підпільників та партизан не отримувала підтримки місцевого, передовсім домінуючого українського населення.