bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Profitabilitas Terhadap Return Saham Dengan Nilai Perusahaan Sebagai Variabel Mediasi Pada Indeks Saham Syariah Indonesia Sektor Industri Barang Konsumsi Periode 2013-2017
Authors: Kumala Destiana 
Published: August 2021

Abstract
This study aims to examine the effect of profitability on stock returns with firm value as the mediating variable. The population in this study are manufacturing companies in the consumer goods industry sector which are listed on the Indonesian Sharia Shock Index (ISSI), the independent variable in this study is profitabilty (X), proxied by using return on equity, the dependent variable stock returns (Y). As measured by the calculation of the stock return formula and the mediating variable, namely the firm value (Z) is proxied by the price to book value (PBV).
This research method uses quantitative research methods using secondary data. Samples were taken based on predetermined criteria. From the sampling method applied, it was obtained 13 manufacturing companies in the consumer goods industry sector that were listed on the Indonesia Sharia Stock Index (ISSI) 2013 – 2017 with data analysis using the SPSS 22 program.
The results showed that profitability had an effect on firm value, profitability had no effect on stock return, firm value had an effect on stock returns, profitability had an effect on stock returns mediated by firm value.
keywords : profitability,stock return, firm value
Application of Sanctions Against State Administrative Officials in Failure to Implement Administrative Court Decisions
Authors: Noor Hendry Julian , Afkar Kardiansyah , Glaser Henning 
Published: August 2021

<p>The purpose of this research is to determine the nature, types, and execution of administrative court decisions, as well as the position of the Prosecutor's office in the Indonesian legal system. This research also examines the legal consequences for officials that do not adhere to administrative court decisions. This is prescriptive legal research and descriptive normative legal research, comprising a statute and case approach, with data collected from primary and secondary legal materials. Firstly, the results showed that the nature of administrative court decisions is <em>erga omnes.</em> The types of administrative court decisions are before and after the dispute subject examination. Furthermore, the execution consists of the obligation to revoke the state administrative decisions, issue new laws due to the petition for negative or positive fictitious choices, and the imposition of compensation and rehabilitation in employment disputes. Secondly, the position of the Prosecutor was categorized into executive power. Thirdly, state administrative officials are obliged to implement administrative court decisions. To not implementing the administrative court decision is a violation of the principle of legality. Legal consequences for government officials that do not subject to and are disobedient to the administrative court decision with legal force should still be imposed administrative sanctions by their superiors.</p><p><strong>Keywords:</strong> Administrative Sanctions; Administrative Court; Prosecutor’s Office.</p>
Freedom of Expression in Malaysia: Compatibility with the International Human Rights Standard
Authors: Yussoff Saidah Fasihah Binti Che , Nordin Rohaida 
Published: August 2021

<p>Malaysia is likely to introduce new laws on freedom of information. However, the important questions are whether the said laws are effective and will have enough bite with the public looking forward to opening government policy. Freedom of information has developed under international human rights law as the right to freedom of expression, including the freedom to seek, receive and impart knowledge and ideas through media, regardless of any frontier. This paper aims to examine freedom of expression under the international realm, scrutinize the said freedom in the Malaysian legal framework, and discuss the proposed enactment of freedom of information laws in Malaysia in conformity with international human rights law. This research uses the qualitative research method. This paper concludes that freedom of information in Malaysia is severely impeded by the enforcement of the Official Secret Act. This paper calls for the repeal or amendment to the Act in conformity with international standards. </p><p><strong>Keywords</strong><strong>:</strong> Expression; Freedom; Expression; Human Right.</p>
Transgender and the Right to Employment in India: Analysing the Trajectories of Discrimination
Authors: K. Mishra Utkarsh , Negi Abhishek 
Published: August 2021

<p>This research aims to investigate the trajectories of discrimination these communities face in the employment sector. While doing so, the authors have emphasized that despite a clear mandate of ‘Right to Work’ in the Constitution of India, policymakers, governments, and the Indian judiciary too has been keen only on laying down framework only concerning ‘Rights at work.’ In this sense, the authors opine that India presently lacks a clear employment non-discrimination framework. Even almost all the labor laws of India stipulate rights and duties post-recruitment scenario. There is an apparent lack of pre-recruitment guidelines. In this light, the authors see the Supreme Court’s recent judgment in the NALSA case recognizing the Transgenders as ‘third gender’ and the efforts of the Indian Parliament to frame a law on the protection of the rights of the transgender people as a silver lining in the cloud. This paper highlights the underpinnings of this development by still emphasizing that something needs to be done more on the front.</p><p> </p><p><strong> </strong><strong>Keywords:</strong> Transgenders; Employment; India.</p>
Prenatal Use of Medication for Opioid Use Disorder and Other Prescription Opioids in Cases of Neonatal Opioid Withdrawal Syndrome: North Carolina Medicaid, 2016–2018
Authors: Austin Anna E. , Bona Vito Di , Cox Mary E. , Proescholdbell Scott , Fliss Michael Dolan , Naumann Rebecca B. 
Published: August 2021

Objectives. To estimate use of medication for opioid use disorder (MOUD) and prescription opioids in pregnancy among mothers of infants with neonatal opioid withdrawal syndrome (NOWS). Methods. We used linked 2016–2018 North Carolina birth certificate and newborn and maternal Medicaid claims data to identify infants with an NOWS diagnosis and maternal claims for MOUD and prescription opioids in pregnancy (n = 3395). Results. Among mothers of infants with NOWS, 38.6% had a claim for MOUD only, 14.3% had a claim for prescription opioids only, 8.1% had a claim for both MOUD and prescription opioids, and 39.1% did not have a claim for MOUD or prescription opioids in pregnancy. Non-Hispanic Black women were less likely to have a claim for MOUD than non-Hispanic White women. The percentage of infants born full term and normal birth weight was highest among women with MOUD or both MOUD and prescription opioid claims. Conclusions. In the 2016–2018 NC Medicaid population, 60% of mothers of infants with NOWS had MOUD or prescription opioid claims in pregnancy, underscoring the extent to which cases of NOWS may be a result of medically appropriate opioid use in pregnancy.
Inflow Performance Analysis of a Horizontal Well Coupling Stress Sensitivity and Reservoir Pressure Change in a Fractured-Porous Reservoir
Authors: Wang Mingxian , Fan Zifei , Zhao Wenqi , Ming Ruiqing , Zhao Lun , Tan Chengqian , Zhang Juan , Li Weiqiang 
Published: August 2021

Abstract
Stress sensitivity has always been a research hotspot in fractured-porous reservoirs and shows huge impacts on well productivity during the depletion development. Due to the continuous reservoir pressure change, accurate evaluation of stress sensitivity and its influence on well productivity is of great significance to optimize well working system. Taking horizontal well trajectory as the research object, the principal focus of this work is on the analysis of inflow performance for a horizontal well coupling stress sensitivity and reservoir pressure change in a fractured-porous reservoir. Firstly, a relationship between permeability damage rate and stress sensitivity coefficient was established to quantitatively evaluate the influence of reservoir pressure and stress sensitivity on reservoir permeability. Secondly, considering stress sensitivity and reservoir pressure drop, a set of practical productivity equations were derived for a horizontal well in a fractured-porous reservoir by adopting the equivalent seepage resistance method. Finally, the influence of relevant important factors on the inflow performance of horizontal wells was discussed in depth. Results show that a positive correlation exists between stress sensitivity coefficient and maximum permeability damage rate. At the same maximum permeability damage rate, high initial reservoir pressure corresponds to low stress sensitivity coefficient. In general, stress sensitivity coefficient mainly ranges from 0 to 0.2. Reservoir pressure change drastically affects the production dynamic characteristics of horizontal wells, and both the inflow performance curve and the production index curve decline and shrink as reservoir pressure decreases. Stress sensitivity is negatively correlated with horizontal well productivity, and the inflow performance/production index curve bends closer to bottom-hole pressure axis, and an inflection point can be observed with the aggravation of stress sensitivity. In addition, horizontal wellbore length and initial reservoir permeability also show significant effects on the inflow performance and are positively correlated with well productivity. For water cut, it has little effect on the well production when bottom-hole pressure drawdown is low, but its effect gets stronger as the drawdown becomes higher. Meaningfully, depending on these newly established productivity equations, a reasonable production system can be quantitatively optimized and achieved for the horizontal wells in fractured-porous reservoirs.
A Low-Sample-Count, High-Precision Pareto Front Adaptive Sampling Algorithm Based on Multi-Criteria and Voronoi
Authors: Wu Changkun , Liang Ke , Sang Hailang , Ye Yu , Pan Mingzhang 
Published: August 2021

Abstract
In this paper, a Pareto front (PF)-based sampling algorithm, PF-Voronoi sampling method, is proposed to solve the problem of computationally intensive multi-objectives of medium size. The Voronoi diagram is introduced to classify the region containing PF prediction points into Pareto front cells (PFCs). Valid PFCs are screened according to the maximum crowding criterion (MCC), maximum LOO error criterion (MLEC), and maximum mean MSE criterion (MMMSEC). Sampling points are selected among the valid PFCs based on the Euclidean distance. The PF-Voronoi sampling method is applied to the coupled Kringing and NASG-II models and its validity is verified on the ZDT mathematical cases. The results show that the MCC criterion helps to improve the distribution diversity of PF. The MLEC criterion and the MMMSEC criterion reduce the number of training samples by 38.9% and 21.7%, respectively. The computational cost of the algorithm is reduced by more than 44.2%, compared to EHVIMOPSO and SAO-MOEA algorithms. The algorithm can be applied to multidisciplinary, multi-objective, and computationally intensive complex systems.
Pretreatment Platelet-to-Lymphocyte Ratio (PLR) is associated with prognosis in gastric cancer patients with immunotherapy
Authors: Gou Miaomiao , Zhang Yong 
Published: August 2021

Abstract
Background: previous studies had demonstrated that system inflammation indexes were associated with prognosis ability in various cancers. We aim to explore the prognostic value of platelet to lymphocyte ratio (PLR) in patients with advanced or metastatic gastric cancer (AGC or MGC) receiving immunotherapy. Method: patients with AGC and MGC who received anti-PD-1 treatment at the Chinese PLA General Hospital between January 2016 and August 2020 were reviewed. The study analyzed the association of PLR and overall survival (OS) or progression-free survival (PFS) and anti-tumor response rate with immunotherapy.Results: 137 patients were included in the final analysis. The area under the curve values of PLR for 6 months PFS was 0.68(P<0.05). The best cut-off value for PLR was 816.43. Patients in PLR <816.43 group had PFS of 7.9m compared to 4.3m in PLR>= 816.43 group (HR = 0.61`, 95% CI, 0.42-0.89, p < 0.001).OS in PLR <816.43 group was longer than PLR>= 816.43 group (11.1m vs 9.2m, HR = 0.62`, 95% CI, 0.42-0.93, p < 0.001). The objective response rate (ORR) and disease control rate (DCR) were 34.1% and 84.6% respectively in PLR <816.43 group while 30.4% and 80.4% in the>= 816.43 group. No significant difference was observed among two group in terms of ORR and DCR (p=0.669, p=0.536). Univariate analysis and multivariate analysis found that PLR was an independent prognosis biomarker for PFS and OS(p<0.05). Conclusions: Pre-treatment PLR was significantly associated with PFS and OS in patients with AGC and MGC who received immunotherapy. Clinicians might consider patients with elevated PLR as one factor for decisions on immunotherapy strategy.
Development and Validation of a Prognostic Nomogram Model for Recurrence of Non-Muscle Invasive Bladder Cancer
Authors: Liu Sanhe , Li Yongzhi , Cui Diansheng , Jiao Yuexia , Duan Liqun , Wang Wei , Dong Zhiqiang , Wei Shaozhong 
Published: August 2021

Abstract
BackgroundDifferent recurrence probability of non-muscle invasive bladder cancer (NMIBC) requests different adjuvant treatments and follow-up strategies. However, there is no simple, intuitive, and generally accepted clinical recurrence predictive model available for NMIBC. This study aims to construct a predictive model for the recurrence of NMIBC based on demographics and clinicopathologic characteristics from two independent centers. MethodsDemographics and clinicopathologic characteristics of 511 patients with NMIBC were retrospectively collected. Recurrence free survival (RFS) was estimated using the Kaplan-Meier method and log-rank tests. Univariate Cox proportional hazards regression analysis was used to screen variables associated with RFS, and a multivariate Cox proportional hazards regression model with a stepwise procedure was used to identify those factors of significance. A final nomogram model was built using the multivariable Cox method. The performance of the nomogram model was evaluated with respect to its calibration, discrimination, and clinical usefulness. Internal validation was assessed with bootstrap resampling. X-tile software was used for risk stratification calculated by the nomogram model. ResultsIndependent prognostic factors including tumor stage, recurrence status, and European Association of Urology (EAU) risk stratification group were introduced to the nomogram model. The model showed acceptable calibration and discrimination (area under the receiver operating characteristic [ROC] curve was 0.85; the consistency index [C-index] was 0.79 [95% CI: 0.76 to 0.82]), which was superior to the EAU risk stratification group alone. The decision curve also proved well clinical usefulness. Moreover, all populations could be stratified into three distinct risk groups by the nomogram model. ConclusionsWe established and validated a novel nomogram model that can provide individual prediction of RFS for patients with NMIBC. This intuitively prognostic nomogram model may help clinicians in postoperative treatment and follow-up decision-making.
Higher Level of Sports Activities Participation During the Five-year Survival Was Associated With Better Quality of Life Among Chinese Breast Cancer Survivors
Authors: Lei Yuanyuan , Ho Suzanne C. , Cheung Ka Li , Yeo Victoria K. M. , Lee Roselle , Kwok Carol , Cheng Ashley , Mo Frankie K. F. , Yeo Winnie 
Published: August 2021

Abstract
BackgroundTo investigate the association between level of sports activities participation at post-diagnosis and quality of life (QoL) among Chinese women with early-stage breast cancer patients during the first five years of survival.MethodsA validated modified Chinese Baecke questionnaire was used to prospectively measure sports activities among a breast cancer cohort at four time-points: baseline (sports activities during the previous 12 months before cancer diagnosis), 18-, 36- and 60-month after diagnosis (sports activities during the previous 12 months before each interview); QoL was measured at the same time. ResultsIn total, 1289, 1125 and 1116 patients were included into the analyses at 18-, 36- and 60-month follow-up, respectively. The percentages of patients who belonged to no [0 metabolic equivalent of task (MET)-hours per week], low-level (<10 MET-hours/week) and high-level (≥10 MET-hours/week) sports activities group were 20.7%, 45.5% and 33.8% at 18-month follow-up, respectively; the corresponding figures at 36- (29.4%, 38.9% and 31.6%, respectively) and 60-month (32.8%, 36.7% and 30.5%, respectively) differed slightly. Using data from the three follow-ups, Generalized Estimating Equations (GEE) analyses showed that higher level of sports activities participation was associated with better QoL in several items, including global health status/QoL, physical functioning, role functioning and emotional functioning (P for trend < 0.05 for all), as well as less symptoms in fatigue, pain, loss of appetite and constipation (P for trend < 0.05 for all). ConclusionsThe present findings in Chinese women with breast cancer provided another important evidence on the beneficial effect of regularly participation in sports activities following cancer diagnosis and patients’ QoL. Health promotion programs should be encouraged with the inclusion of regular sports activities after breast cancer diagnosis.
Artificial Perches for Birds in Deforested Areas Favour a Seed Rain Similar to Woodland Remnants
Authors: Guidetti Brenda Yamile , Dardanelli Sebastian , Miño Fátima María Lourdes , Amico Guillermo César 
Published: August 2021

Abstract
The lack of seeds represents one of the highest difficulties to overcome for the ecological restoration of areas that have been deforested. This study evaluates the effectiveness of artificial perches in increasing the abundance and species richness of bird-dispersed seeds and the similitude of seed rain composition (origin and habit of plant seeds), of deforested areas with and without artificial perches in relation to woodland remnants that serve as seeds source. The experiment took place in two sites of the Espinal ecoregion, Argentina. We found that in deforested areas, perches increased seed abundance and species richness in the seed rain in comparison with deforested areas without artificial perches. The species composition under artificial perches was similar to the seed rain dispersed in the woodland. However, a decrease in the richness of native species was significant in the deforested area, probably due to behavioral differences between opportunistic and obligate frugivorous. Seed of trees and shrubs species were well represented in the seed rain under artificial perches. Results from this study contribute to the understanding of nucleation and recovery mechanisms used by nature that reflect ecosystem resilience. We recommend using artificial perches in deforested areas with potential for recovery because it is an efficient technique to promote the entry of birds and increase seed rain, preserving features of the original environment. However, using artificial perches should be avoided in sites with potentially invasive non-native species.
Health-Related Quality of Life with Cervical Cancer and Precancer: A Cross-Sectional Study in Yunnan Province, China
Authors: Zhao Min , Zhang Mengjiao , He Lianju , Zuo Chunmei , Ding Songrui , Golden Allison Rabkin , Cai Le 
Published: August 2021

Abstract
Objectives Cervical cancer is the fourth most common cancer in women, with an estimated 600,000 new cases and 340,000 deaths worldwide in 2020. However, there remains limited understanding of the association between individual socioeconomic status (SES) and clinical characteristics and health-related quality of life (HRQoL) of women with cervical precancerous lesions and cancer worldwide, including in China. This study investigates socioeconomic and clinical variations in HRQoL of women with cervical precancerous lesions and cancer in Yunnan Province, China.MethodsThe present study employed a cross-sectional survey design. An EQ-5D-5L questionnaire was used to assess HRQoL of 400 patients with cervical precancerous lesions and cancer in Yunnan Province, China from 2019 to 2020. ANOVA and independent samples t-tests were performed to identify the independent variables associated with the EQ-5D-5L utility scores and VAS scores. Predictors of the utility scores were confirmed using a Tobit regression model.ResultsThe mean of cervical precancerous lesions and cancer patients’ EQ-5D-5L utility scores was 0.939 (SD, 0.104) and the mean of VAS scores was 80.84(SD, 16.551). Patients aged 40-59 years (β=-0.037, p=0.005), patients who were not aware of the human papillomavirus (HPV) vaccine (β=-0.032, p=0.004), and patients who underwent radical hysterectomy (β=-0.036, p=0.006) had significantly lower utility scores, whereas having high monthly household income (β=0.023, p=0.033) was significantly associated with higher EQ-5D-5L utility scores. Age (p=0.023) was statistically significant in differences in patients’ VAS scores. Anxiety/depression was the most frequently reported issue (35.75%) among participants. ConclusionsFuture cervical cancer prevention and treatment guidelines should focus on low-income women, women aged 40-59 years, and those lacking knowledge about cervical cancer prevention.
Comparison of Two Methods of Removing Totally Implantable Vascular Access Devices- A Single-Center Experience
Authors: zhang yanshou , Han Lei , Liu Yunjiang 
Published: August 2021

Abstract
In recent years, totally implantable vascular access devices (TIVADs) are widely used for infusion of high-concentration chemotherapeutic drugs and total parenteral nutrition solution, mainly in cancer patients. While there is no definite optimal time and detailed surgical procedures for the removal of TIVADs. The purpose of the study was to investigate the effects and complications of different removal approaches of totally implantable vascular access devices (TIVADs). A retrospective analysis was performed on 205 breast cancer patients who underwent TIVAD removal between June 2019 and November 2019. The patients were randomly divided into two groups. There were 102 cases in group A, in which the port was removed before the catheter. There were 103 cases in group B, in which the catheter was removed before the port. The systematic analysis focused on operation time and postoperative complications (pain, local skin infection, and hematoma). There were no significant differences in postoperative pain, wound infection, and hematoma between the two groups (P>0.05). The operation time was significantly shortened in group A (P<0.01).There were no significant differences in postoperative complications between the two groups. The operation time could be significantly reduced by adopting the strategy of removing the port before the catheter.