bluuebunny/crossref_metadata_2025_split huggingface dataset:
Match made in Heaven (or Hell?): Understanding the High Incidence of Tinder Rapes in Spain
Authors: Sayeras Josep , Rueff-Lopes Rita 
Published: February 2025

Abstract
A recent report revealed that 21.7% of women in Spain who went on a Tinder date were raped. These findings suggest that the incidence of sexual violence on Tinder dates in Spain may be higher than in other social contexts. This study explores the experiences of Tinder users in Spain to understand the factors contributing to this phenomenon and to propose measures for enhancing user safety. We conducted four focus groups separated by sociodemographic characteristics that replicated the typical victims’ and perpetrators’ profile (age and gender). Male participants initially expressed disbelief and attributed the phenomenon to Tinder’s environment, pathological behavior, pornography, and women’s actions. In contrast, female participants accepted the statistic as reflective of real-world issues, dismissing pathological explanations and highlighting systemic victim-blaming, fear-induced paralysis, and the impact of pornography as key factors. The findings underscore a significant disparity in perceptions between genders, with males often minimizing or misattributing the problem, while females recognizing deeper systemic issues. These insights suggest a need for targeted interventions and policies that address both the behavioral and perceptual factors contributing to sexual violence on dating platforms.
Ornamental Plant Safety and Weed Control with Indaziflam
Authors: Aulakh Jatinder S , Witcher Anthony , Kumar Vipan 
Published: February 2025

Abstract
Indaziflam was evaluated in Connecticut and Tennessee, USA, for weed control and safety of container-grown ornamental plants. Indaziflam was applied at 49, 98, or 196 g ha-1 to container-grown ornamental plants on an outdoor gravel pad and preemergence or early postemergence to weeds in greenhouse. Ornamental plants were treated twice annually in 2020 and 2021 in Connecticut, and in 2019 and 2020 in Tennessee, with approximately six weeks between applications. Chinese pyramid juniper, common juniper, eastern hemlock, eastern white pine, and Norway spruce in Connecticut, USA, and 'Andorra Compacta’ creeping juniper and 'Black Dragon’ Japanese cedar, ‘Blue Rug’ creeping juniper, and ‘Blue Pfitzer’ Chinese pyramid juniper in Tennessee, USA, were not injured with indaziflam regardless of rate applied. Preemergence application of indaziflam reduced densities of creeping woodsorrel, hairy bittercress, giant foxtail, and large crabgrass 72 to 100%, depending upon the indaziflam rate applied, by 28 d after treatment (DAT). When applied early postemergence, indaziflam provided 97 to 99% control of creeping woodsorrel (1- to 2-leaf), fringed willowherb (4- to 6-leaf), hairy bittercress (cotyledon to 1-leaf), and mouse-ear chickweed (2- to 4-leaf) by 28 DAT. Compared with the nontreated control, the total fresh shoot biomass reduction was 86 to 100% and 78 to 100% following preemergence or postemergence applications. Indaziflam offers a new site-of-action with excellent safety and weed control in the tested ornamental plants.
Rice cultivar tolerance to preemergence- and postemergence-applied fluridone
Authors: Souza Maria C.C.R. , Norsworthy Jason K. , Carvalho-Moore Pâmela , Godar Amar , Fernandes Samuel B. , Butts Thomas R. 
Published: February 2025

Abstract
Fluridone was registered for use in rice in 2023, offering a new herbicide site of action for growers. However, little information is available on rice tolerance to this herbicide. Field experiments conducted in 2022 and replicated in 2023 near Colt, AR, evaluated the tolerance of twelve rice cultivars to fluridone, applied preemergence or at the 3-leaf growth stage, in separate experiments. Each experiment consisted of one cultivar. Fluridone rates were 0, 168 (1× label rate), and 336 (2× label rate) g ai ha⁻¹ in all experiments. Visible injury varied between years in all experiments, likely due to different environmental conditions. In 2022, injury following preemergence applications of fluridone was below 25% across cultivars. In contrast, in 2023, injury ≥ 30% occurred to five cultivars, with a maximum of 58% observed for the cultivar ‘DG263L’. Across both years, only three cultivars achieved injury ≥ 20% following fluridone applications at the 3-leaf rice. Fluridone negatively affected shoot density, groundcover, chlorophyll content, and days to 50% heading in most cultivars when applied preemergence. When fluridone was applied to 3-leaf rice, at least one of the variables evaluated was negatively affected in two and nine cultivars in 2022 and 2023, respectively. Grain yield reductions of at least 18% were observed in eight cultivars in 2022, and a grain yield decrease from 9% to 49% in eight cultivars occurred in 2023 in the preemergence experiments. Fluridone applied at the 3-leaf rice did not cause a yield penalty to any cultivar in 2022, whereas in 2023, eight cultivars had a yield loss. Yield loss in ‘DG263L’ occurred at the 1× rate in both experiments, indicating this cultivar appears sensitive to fluridone, regardless of the application timing. Based on these findings, fluridone tolerance is cultivar-dependent. Furthermore, preemergence applications of fluridone in rice should be avoided.
Hollows on Mercury: Global Classification of Degradation States and Insight Into Hollow Evolution
Authors: Deutsch Ariel N. , Bickel Valentin T. , Blewett David T. 
Published: February 2025

AbstractHollows are small, shallow, irregularly shaped landforms, widespread across Mercury, interpreted to have formed via loss of volatiles. Here, we present the first global analysis of hollow degradation states using a new machine learning‐derived global catalog. We define three classes, grading from younger/potentially active “Stage 1” (sharp morphology, high visible reflectance) to older/potentially expired “Stage 3” (softened morphology, reflectance similar to that of surroundings). Most analyzed hollows are Stage 1 (N = 1,545 individual hollows), which are more common than Stage 2 (N = 1,111) or Stage 3 (N = 10) hollows near the equator, consistent with the idea that insolation is a primary driver for hollow initiation/growth. Areas where Stage 2 hollows are more common than Stage 1 hollows may indicate regions of relative volatile depletion. Stage 3 hollows are rare, suggesting they are systematically missed during image review, or that hollows on Mercury are mostly young, have been recently reactivated, or are quickly erased once they become inactive. Temperature may limit hollow growth, given that only small hollows are identified in the coldest terrains. There is no meaningful difference in the distribution of hollow sizes between stages, suggesting that their morphological and reflectance properties are not substantially muted until they are fully grown. Stage 1 hollows are more commonly found on steeper slopes than nearby Stage 2 hollows, suggesting that slopes may be an important control on how long hollows remain active. Our hollow classifications are openly available and can help to inform global‐scale studies of hollow evolution, and upcoming targeting efforts by the ESA/JAXA BepiColombo mission.
MAPK13 phosphorylates PHGDH and promotes its degradation via chaperone-mediated autophagy during liver injury
Authors: Xing Ru , Liu Ruilong , Man Yongxiao , Liu Chen , Zhang Yajuan , Gao Hong , Yang Weiwei 
Published: February 2025

Abstract
Drug-induced liver injury (DILI) is the leading cause of acute liver failure and poses a significant clinical challenge in both diagnosis and treatment. Serine synthesis pathway (SSP) links glycolysis to one-carbon cycle and plays an important role in cell homeostasis by regulating substance synthesis, redox homeostasis and gene expression. However, the regulatory mechanism of SSP in DILI remains unclear. Phosphoglycerate dehydrogenase (PHGDH) is the rate-limiting enzyme in SSP. Here we show that during DILI, mitogen-activated protein kinase 13 (MAPK13) is activated and then phosphorylates PHGDH at serine 371 upon oxidative stress, which triggers PHGDH protein degradation via chaperone-mediated autophagy (CMA) pathway. PHGDH degradation suppresses SSP and glutathione production, thereby exacerbating DILI and cholestatic liver injury. Importantly, both MAPK13 inhibition and dietary serine supplementation ameliorates these liver injuries. Our finding demonstrates a unique regulatory mechanism of SSP, in which MAPK13 phosphorylates PHGDH and promotes its CMA degradation, establishes its critical role in DILI and cholestatic liver injury, and highlights the therapeutic potential of MAPK13 inhibitor or dietary serine to treat these liver injuries.
Blood pressure elevations post-lenvatinib treatment in hepatocellular carcinoma: a potential marker for better prognosis
Authors: Shibata Keisuke , Akasaki Yuichi , Tokushige Akihiro , Nitta Mina , Kawasoe Shin , Kubozono Takuro , Oda Kohei , Kumagai Kotaro , Mawatari Seiichi , Ohishi Mitsuru 
Published: February 2025

Abstract
Lenvatinib is a tyrosine kinase inhibitor that effectively inhibits vascular endothelial growth factor signaling and is used for treating hepatocellular carcinoma. However, angiogenesis inhibitors often cause hypertension. Although lenvatinib-induced hypertension has been proposed as a potential surrogate marker for better prognosis, studies on blood pressure elevations and outcomes following lenvatinib initiation are limited. This study included 67 patients who underwent lenvatinib therapy at the Department of Gastroenterology, Kagoshima University Hospital, between May 2018 and December 2023. The median age of the cohort was 71 years, and 82.1% of the patients were male. The median blood pressure at admission was 128/73 mmHg, which significantly increased to 136/76 mmHg the day after lenvatinib administration. Grade 3 hypertension (≥160/100 mmHg) occurred in 37.3% of patients during hospitalization. The median increase in systolic blood pressure from admission to its peak during hospitalization was 26 mmHg. Patients who experienced an increase in blood pressure of ≥26 mmHg were classified into the blood pressure elevation group, which showed a significantly lower mortality rate than that of the blood pressure non-elevation group (35.3% vs. 81.8%, log-rank p = 0.007), even after adjusting for age, sex, disease stage, performance status, and liver reserve function. This study demonstrated that patients who experienced earlier blood pressure elevation after lenvatinib administration had lower overall mortality rates. These findings suggest that blood pressure elevations after lenvatinib initiation may serve as valuable prognostic indicators in patients with cancer undergoing lenvatinib therapy.
Strong and early monkeypox virus-specific immunity associated with mild disease after intradermal clade-IIb-infection in CAST/EiJ-mice
Authors: Meyer zu Natrup Christian , Clever Sabrina , Schünemann Lisa-Marie , Tuchel Tamara , Ohrnberger Sonja , Volz Asisa 
Published: February 2025

Abstract
Monkeypox virus (MPXV) is a zoonotic poxvirus long endemic in West and Central Africa. Outbreaks, first the global spread of clade II outside Africa in 2022, and since 2023 the accelerating spread of clade I in central Africa, point to MPXV adaptations that pose the risk of it becoming more transmissible in humans. Animal models mimicking the clinical disease outcome in humans are important to better understand pathogenesis, host tropism, and the contribution of genetic mutations. Here, we demonstrate that MPXV infection via tail scarification in CAST/EiJ mice is an appropriate animal model to mimic human mpox. In our study, disease outcome is milder in clade IIb than clade IIa-infected mice, which is associated with enhanced immunogenicity early during infection. This suggests that clade IIb more efficiently activates host immune responses, highlighting how this animal model could facilitate studying new MPXV variants to help develop efficient antivirals and preventive measures.
Jointly exploring client drift and catastrophic forgetting in dynamic learning
Authors: Babendererde Niklas , Fuchs Moritz , Gonzalez Camila , Tolkach Yuri , Mukhopadhyay Anirban 
Published: February 2025

Abstract
Federated and Continual Learning have emerged as promising paradigms for the privacy-aware use of Deep Learning in dynamic environments by addressing spatial and temporal constraints on data availability. However, Client Drift and Catastrophic Forgetting are fundamental obstacles to ensuring robust performance. Existing work only addresses these problems separately, neglecting the fact that the root cause behind them, namely an unexpected shift in the data distribution, is connected. We propose a unified analysis framework for building a controlled test environment where we can jointly model spatial and temporal shifts, more closely emulating real dynamic settings. By generating a 3D landscape of the combined performance impact, we show that a moderate combination of both shifts can even improve the performance of the resulting model (“Generalization Bump”). We apply a simple and commonly used method from continual learning in the federated setting and observe this reoccurring phenomenon.
Testing Feasibility of a Self-Administered Hearing Test for Patients With Progressive Apraxia of Speech and Aphasia
Authors: Utianski Rene L. , Meade Gabriela , Meyer Megan J. , Duffy Joseph R. , Clark Heather M. , Whitwell Jennifer L. , Josephs Keith A. , Poling Gayla L. 
Published: February 2025

Background and Objectives:
Hearing loss is relatively common in older individuals, and individuals with frontotemporal lobar degeneration (FTLD) are no exception; this can exacerbate communication difficulties stemming from speech-language impairments. The co-occurrence of these symptoms can contribute to increased frustration and isolation for patients and their communication partners. The objective of this study was to evaluate the feasibility of self-administered hearing testing. Ultimately, this could be administered remotely, which would increase access to assessment and inform management for this population.

Method:
Seventeen patients with underlying FTLD, clinically presenting with progressive apraxia of speech with and without agrammatic aphasia, independently completed the Home Hearing Test supervised while in office.

Results:
Three patients self-reported hearing loss, but results for 100% recommended formal evaluation. Eleven patients demonstrated good test accuracy. Six patients had “poor” or not computable accuracy; among them, five had evidence of cognitive impairment and/or behavioral changes, and one had known severe hearing loss, although differences between those with good and poor test accuracy were not significant. Patients with poor test accuracy had more difficulty with limb praxis.

Conclusions:
Most participants independently completed the test, though some had reduced test accuracy that may have been associated with cognitive impairment and/or limb apraxia. This study supports the need for hearing screenings in all patients with progressive apraxia of speech and aphasia and highlights both the feasibility and caution required in implementing self-administered testing protocols. Further work should evaluate the feasibility of in-home hearing screenings in a broader range of FTLD phenotypes and directly compare sensitivity and specificity of hearing loss detection with in-clinic administration.

Supplemental Material:

https://doi.org/10.23641/asha.28306613
How do Clinicians Use Electronic Health Records for Respiratory Support Decisions? A Qualitative Study in Critical Care
Authors: Zhang Tianyi , Mosier Jarrod , Subbian Vignesh 
Published: February 2025

Abstract
Objectives Selecting appropriate respiratory support in critical care is complex, and some decisions require information that may be unknown when the treatment assignment is necessary. Digital technologies such as electronic health records (EHR) are essential components in critical care medicine to support respiratory support care delivery and management of patients with respiratory failure. However, there are limited studies on EHR use that enable clinical decisions related to respiratory support. The objective of this study is to understand how clinicians use EHRs for their decision-making related to respiratory support in intensive care units (ICUs).
Methods Using a socio-technical systems approach, we conducted nine observations with nine different care teams for 35 hours at two ICUs within a large academic hospital system. We created a journey map to illustrate clinicians' respiratory support decision-making processes. We identified barriers related to decision-making processes within the ICU socio-technical work context and characterized them based on macro-cognitive functions to derive themes that can capture the decision-making patterns associated with EHR use.
Results Our analysis identified three overarching themes that represent clinicians' use of EHR for their respiratory support decisions: (1) fragmented information and tasks for individual sensemaking; (2) EHR workarounds for collaborative decision-making; and (3) interruptive order entry and order execution. These three themes represent three major sequential stages (i.e., before, during, and after morning rounds) related to clinicians' respiratory support decision-making processes, and their interaction with EHR significantly varies between stages.
Conclusion Our findings reflected different EHR use patterns before, during, and after morning rounds for decision-making related to respiratory support. These findings indicated potential opportunities for diagnostic clinical decision support (CDS) to facilitate respiratory support decisions.
High-energy irradiation of matrix isolated acetic acid yields a ·CH3⋯CO2 complex: A spectroscopic and ab initio study
Authors: Zasimov Pavel V. , Tyurin Daniil A. , Mirskoi Georgii A. , Sanochkina Elizaveta V. , Feldman Vladimir I. 
Published: February 2025

The mechanism of the chemical transformations of isolated small organic molecules induced by high-energy radiation is of basic interest for astrophysics and astrochemistry. In this work, we first applied a combination of electron paramagnetic resonance (EPR) and Fourier-transform infrared (FTIR) spectroscopy to identify the products of the radiation-induced transformations of isolated CH3COOH and CD3COOH molecules. As revealed by EPR, ·CH3 (or ·CD3) is the principal primary radical generated from acetic acid in solid argon and xenon, while the FTIR results suggest that this radical is trapped mainly in the form of the ·CH3⋯CO2 radical–molecule complex. The assignment of this previously unknown complex was based on the complexation-induced shifts of the absorption bands corresponding to CH3OPLA and CO2bend vibration modes, confirmed by analysis of the kinetic curves, photochemical behavior, and comparison with the results of ab initio computations at the spin-unrestricted coupled-cluster singles, doubles, and perturbative triples level of theory. Most likely, the complex in matrices adopts the geometry close to the theoretically predicted structure with Cs symmetry stabilized by the C⋯C and O⋯H interactions. It was suggested that the complex could be produced via the intermediate formation of a CH3COOH+· radical cation deprotonating to the CH3COO· radical, which promptly decomposed to ·CH3 + CO2 fragments. We believe that the results obtained in this study may contribute to a better understanding of the processing of acetic acid molecules in astrophysically relevant ices under high-energy irradiation and give a valuable insight into the understanding of weak intermolecular interactions involving radicals relevant to atmospheric chemistry, combustion, and carbon dioxide conversion.
Rubber wear: Experiment and theory
Authors: Persson B. N. J. , Xu R. , Miyashita N. 
Published: February 2025

We study the wear rate (mass loss per unit sliding distance) of a tire tread rubber compound sliding on concrete paver surfaces under dry and wet conditions, at different nominal contact pressures of σ0 = 0.12, 0.29, and 0.43 MPa, and sliding velocities ranging from v = 1 μm s−1 to 1 cm s−1. We find that the wear rate is proportional to the normal force and remains independent of the sliding speed. Sliding in water and soapy water results in significantly lower wear rates compared to dry conditions. The experimental data are analyzed using a theory that predicts wear rates and wear particle size distributions consistent with the experimental observations.
Cold H + O2 collisions: Impact of resonances, geometric phase, and alignment
Authors: Wang Junyan , Hu Xixi , Guo Hua , Xie Daiqian 
Published: February 2025

We report a quantum mechanical investigation of cold inelastic collisions between H and O2 (Ec ≤ 10 K) using a recently developed diabatic potential energy matrix for the lowest two 2A″ states coupled by conical intersections. Time-independent close coupling calculations were carried out in both the adiabatic and nonadiabatic representations in order to delineate the impact of the geometric phase (GP) on scattering. Both adiabatic and nonadiabatic results show many resonance peaks dominated by single partial waves. The inclusion of GP is found to have a large impact on the scattering resonances and more generally on both the integral cross section (ICS) and differential cross section (DCS). In addition, our investigations show that both ICS and DCS could be controlled by the initial alignment of O2, and the effect of the GP also manifest in the stereodynamics of the H + O2 collisions.
Accuracy and Stability study of two-way time transfer in Cis-lunar space
Authors: Liu Tong , Qin Cheng-Gang , Pu Jing-Hui , Yang Yongzhang , Wang Wenbin 
Published: February 2025

Abstract
The realization of clock synchronization and syntonization via inter-satellite link is of vital importance for navigation, space-based VLBI experiments and precision tests of fundamental physics. We study the accuracy and stability of time and frequency transfer via inter-satellite link in cis-lunar space. A relativistic time transfer model using microwave dual one-way ranging is developed. Taking the DRO-LEO inter-satellite link as an instance, sub-nanoseconds level accuracy is achieved. We analyze the error in orbit determination of LEO satellite and DRO satellite. With the models of relative velocity correction, relativistic frequency shift and Shapiro delay, the stability of time transfer is studied. The result shows the DOWR microwave link would support clock synchronization with a time stability of better than 14.2ps over 1000s, better than 100.1ps over one day, with the accuracy constraints on the orbit determination of the LEO satellite 10cm and DRO satellite 50m in position. If the longer time stability of hardware delay reaches ps level, the performance of DOWR time transfer link can be further improved to support the distribution of the time-frequency scale established by an active hydrogen maser with a frequency stability of 2×10-15 over one day.We estimated that high-performance DRO-LEO time and frequency comparisons may support the gravitational redshift tests at a 10−6 level and the space-based VLBI experiments to improve the orbit determination of deep-space probes by one to two orders of magnitude.&#xD;