bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Oceanic South Atlantic Convergence Zone Episodes on Regional SST Anomalies: the Roles of Heat Fluxes and Upper-Ocean Dynamics
Authors: Pezzi Luciano Ponzi , Quadro Mario F. L. , Lorenzzetti João , Miller Arthur J , Rosa Eliana B , Lima Leonardo , Sutil Ueslei A 
Published: December 2021

Abstract
The South Atlantic Convergence Zone (SACZ) is an atmospheric system occurring in austral summer on the South America continent and sometimes extending over the adjacent South Atlantic. It is characterized by a persistent and very large, northwest-southeast-oriented, cloud band. Its presence over the ocean causes sea surface cooling that some past studies indicated as being produced by a decrease of incoming solar heat flux induced by the extensive cloud cover. Here we investigate ocean-atmosphere interaction processes in the Southwestern Atlantic Ocean (SWA) during SACZ oceanic episodes, as well as the resulting modulations occurring in the oceanic mixed layer and their possible feedbacks on the marine atmospheric boundary layer. Our main interests and novel results are on verifying how the oceanic SACZ acts on dynamic and thermodynamic mechanisms and contributes to the sea surface thermal balance in that region. In our oceanic SACZ episodes simulations we confirm an ocean surface cooling. Model results indicate that surface atmospheric circulation and the presence of an extensive cloud cover band over the SWA promote sea surface cooling via a combined effect of dynamic and thermodynamic mechanisms, which are of the same order of magnitude. The sea surface temperature (SST) decreases in regions underneath oceanic SACZ positions, near Southeast Brazilian coast, in the South Brazil Bight (SBB) and offshore. This cooling is the result of a complex combination of factors caused by the decrease of solar shortwave radiation reaching the sea surface and the reduction of horizontal heat advection in the Brazil Current (BC) region. The weakened southward BC and adjacent offshore region heat advection seems to be associated with the surface atmospheric circulation caused by oceanic SACZ episodes, which rotate the surface wind and strengthen cyclonic oceanic mesoscale eddy. Another singular feature found in this study is the presence of an atmospheric cyclonic vortex Southwest of the SACZ (CVSS), both at the surface and aloft at 850 hPa near 24°S and 45°W. The CVSS induces an SST decrease southwestward from the SACZ position by inducing divergent Ekman transport and consequent offshore upwelling. This shows that the dynamical effects of atmospheric surface circulation associated with the oceanic SACZ are not restricted only to the region underneath the cloud band, but that they extend southwestward where the CVSS presence supports the oceanic SACZ convective activity and concomitantly modifies the ocean dynamics. Therefore, the changes produced in the oceanic dynamics by these SACZ events may be important to many areas of scientific and applied climate research. For example, episodes of oceanic SACZ may influence the pathways of pollutants as well as fish larvae dispersion in the region.
Traditional usage of underutilized aquatic plants found in the Imphal valley of Manipur
Authors: Devi Okram Abemsana , Saikia Mridula Barooah , Ningthoujam Sanjoy Singh 
Published: December 2021

Abstract
The paper focuses on the traditional usage of aquatic plants found in the wetland areas of the Imphal valley of Manipur. From the survey, 30 aquatic plants have been collected use for the management of various health conditions. Most of the collected plants consume as daily food items, some used for specic remedial purposes in the treatment of certain types of ailments and diseases like cough, fever, ulcer, piles, diarrhea, jaundice, skin diseases, rheumatic pain, diabetes, hypertension, urinary troubles, body pain, respiratory problems, urinary problems, cardiovascular diseases, etc. Accordingly, different parts of the plant are used as a single item or by mixing with other ingredients in various forms of fresh or raw, culinary, or as a tonic or dry or powder form to treat the diseases. The aquatic plants also incorporate in the preparation of various traditional dishes. 70% of collected wetland plants are marketable provides a means of livelihood and source of income for the poor and needy people. Therefore, proper documentation and preservation of traditional knowledge are essential that may provide useful for future generations through research in pharmaceuticals and drug discovery.
Clinical Features of POEMS Syndrome In Southeast Asia: A Literature-Based Study
Authors: Prado Mario B. , Adiao Karen Joy 
Published: December 2021

Abstract
Purpose: To determine and analyze the clinical characteristics of POEMS Syndrome among Southeast Asian countries.Methods: We searched the literature using a pre-specified inclusion and exclusion criteria and using the search terms “[(POEMS) or (Takatsuki) or (PEP) or (Crow Fukase) and (syndrome)] AND [Countries/People of Southeast Asia]”.Results: Seven studies, including 5 case reports, 1 case series and 1 correspondence letter containing 8 patients were eligible for analysis. The median age of onset was 54 years, while the median duration to correct diagnosis was 5.5 months. The most common initial presentation was weakness (4/6) with 50% initially diagnosed as chronic inflammatory demyelinating polyneuropathy. On physical examination, 100% had evidence of length dependent polyneuropathy, 80% had papilledema, 75% had edema/effusion, 86% had skin changes and 67% had organomegaly. All had abnormal NCS and CT scan while 1 tested negative for monoclonal gammopathy restricted to lambda. Only 2 had VEGF results, one of which was normal. Melphalan and steroid combination was the most common treatment given with only 1 case dying of sepsis. Conclusion: Although the number of cases in Southeast Asia is lower, which can be attributed to difference in ethnicity and geographical location, the presenting signs and symptoms of this condition was similar to other countries. However, the new proposed criteria may not be applicable in the region as only few countries are capable of doing VEGF testing.
Stroke and Internal Carotid Dissection as the First Manifestation of Giant Cell Arteritis: A Case Report
Authors: Hashami Leila , Ketabforoush Arsh Haj Mohamad Ebrahim 
Published: December 2021

Abstract
Introduction: Giant Cell Arteritis (GCA) is a systemic vasculitis that involves medium-sized and larger arteries.GCA rarely can affect the brain-arteries, resulting in ischemic strokes and transient ischemic attacks, whereby the most affected region is vertebrobasilar. Also, it's very unusual that cocurate with large artery dissections. We describe a patient with anterior brain territory stroke and right internal carotid dissection as the first manifestation of GCA.Case report: A 51-year-old man was presented with sudden onset of right-side blurred vision, frozen movements, and ptosis in the right eye and left side paresis. There was a history of right-sided frontotemporal headache, diabetes mellitus, and dyslipidemia. The Laboratory tests show erythrocyte sedimentation rate (ESR)=90, C-reactive protein (CRP)=15mg/L. CT scan and brain MRI indicated an acute ischemic infarction in the right frontal region. CT-Angiography has shown internal carotid artery dissection. Due to the presentation and lab tests, we started Methylprednisolone 1 gr for treating GCA, and temporal artery biopsy was positive for GCA in pathology findings. After ten days, inflammatory markers were reduced (ESR:40). Besides improving headaches, there was no significant change in eye deficits and reduction of left limb's force.Conclusion: Due to the noisy symptoms in patients with Stroke and carotid dissection, the diagnosis of GCA may be neglected as an underlying cause. The association of high CRP levels and the rate of ESR with Stroke, although nonspecific, should draw some attention to vasculitis, topped by GCA.
Discovery of EDA-Complex Photocatalyzed Reactions Using Multidimensional Image Processing: Iminophosphorane Synthesis as a Case Study
Authors: Silva Rodrigo , Batista Gabriel , Brocksom Timothy , de Oliveira Kleber 
Published: December 2021

Abstract
Herein, we report a multidimensional screening strategy for the discovery of EDA-complex photocatalyzed reactions using only photographic devices (webcam, cellphone) and TLC analysis. An algorithm was designed to identify automatically EDA-complex reactive mixtures in solution from digital image processing in a 96-wells microplate and by TLC-analysis. The code highlights the region of absorption of the mixture in the visible spectrum, and the quantity of the color change through grayscale values. Furthermore, the code identifies automatically the blurs on the TLC plate and classifies the mixture as colorimetric reactions, non-reactive or potentially reactive EDA mixtures. This strategy allowed us to discover and then optimize a new EDA-mediated approach for obtaining iminophosphoranes in up to 90% yield.
Modifiable Factors Associated with Reversion from Mild Cognitive Impairment to Cognitively Normal Status: A Prospective Cohort Study
Authors: Sha Feng , Zhao Ziyi , Wei Chang , Li Bingyu 
Published: December 2021

Abstract
Background
Previous studies found that about 24% of the mild cognitive impairment (MCI) patients reverse to cognitively normal (CN) status. However, it is unclear which modifiable factors are associated with this reversion.
Method
We conducted a prospective community-based cohort study based on 2002-2018 Chinese Longitudinal Health Longevity Survey (CLHLS). Of 35,474 older adults from 22 provinces in China in the 5 waves of CLHLS, 7,422 eligible participants with MCI were included. Multivariable Cox regression with least absolute shrinkage and selection operator (LASSO) penalty for variable selection was adopted to investigate the associations between reversion to CN and potential modifiable dietary/lifestyle, cardiometabolic, and psychological factors.
Results
Our analysis included 7,422 MCI participants [average age: 90.0 (SD 9.5) years]. Among these participants, 1,604 (21.6%) reversed from MCI to CN with a mean (SD) follow-up of 2.9 (1.8) years. Several dietary/lifestyle factors, including daily consumption of fresh fruits (Hazard Ratio [HR]: 1.28, 95% CI: 1.15 to 1.42; P༜.001), engagement in reading (HR: 1.24, 95% CI: 1.00 to 1.54; P =.047), housework (HR: 1.21, 95% CI: 1.08 to 1.35; P =.001), and mah-jong or other card games (HR: 1.23, 95% CI: 1.08 to 1.39; P =.001), were positively associated with possibility of reversion. Cigarette smoking (HR: 0.92, 95% CI: 0.84 to 1.00; P= .041) and duration of alcohol drinking (HR: 0.97, 95% CI: 0.94 to 0.99; P = .012) were negatively associated with possibility of reversion. None of the modifiable cardiometabolic and psychological factors was found to be significantly associated with reversion to CN. Difference was identified among different age and gender group.
Conclusion
This study identified several dietary/lifestyle factors associated with MCI reversion that may transfer into large-scale dementia prevention practices.
NMR analysis of pine tree oleoresin composition of the Pinus subgenus
Authors: Скаковский Е.Д. , Тычинская Л.Ю. , Гапанькова Е.И. , Латышевич И.А. , Шутова А.Г. , Шиш С.Н. , Ламоткин С.А. 
Published: December 2021

Методом ЯМР проведен анализ состава живиц восьми видов сосен подрода Pinus: черной австрийской (P. nigra), аллепской (P. halepensis), горной (P. montana), жесткой (P. rigida), Коха (P. kochiana Klotsch), Муррея (P. murrayana Balf), обыкновенной (P. sylvestris) и Палласа (P. nigra subsp. pallasiana), произрастающих в различных районах. Кроме того, исследовано содержание смоляных кислот, выделенных в 1963 г. из живиц трех видов сосен того же подрода: черной австрийской, крючковатой (P. uncinata) и кулундинской (P. sylvestris ssp. Kulundensis). Установлено, что состав живиц названных видов сосен хорошо описывается наличием восьми смоляных кислот (абиетиновая, дегидроабиетиновая, изопимаровая, левопимаровая, неоабиетиновая, палюстровая, пимаровая и сандаракопимаровая) и девяти монотерпенов (камфен, 3-карен, лимонен, мирцен, α-пинен, β-пинен, терпинолен, βфелландреен, п-цимол). Количественное содержание этих смоляных кислот зависит от многих факторов (вида сосен, времени и места сбора живицы, а также условий сбора и хранения образцов). Кроме того, наблюдаются реакции изомеризации и окисления, приводящие к перераспределению состава. В изученных живицах содержание монотерпенов сильно отличается, являясь наименьшим у сосны аллепской и наибольшим у сосны обыкновенной.
The NMR method was used to analyze oleoresin composition of eight species of Pinus subgenus: Austrian black (P. nigra), Alleps (P. halepensis), mountain (P. montana), hard (P. rigida), Koch (P. kochiana Klotsch), Murray (P. murrayana Balf), common (P. sylvestris) and Pallas (P. nigra subsp. pallasiana) growing in different areas. In addition, the content of resin acids isolated in 1963 from the oleoresins of three species of pines belonging to the same subgenus: black Austrian, hooked (P. uncinata) and Kulunda (P. sylvestris ssp. Kulundensis) was studied. It was found that the oleoresin composition of the named pine species is well described by the presence of eight resin acids (abietic, dehydroabietic, isopimaric, levopimaric, neoabietic, palustrine, pimaric and sandaracopymaric) and nine monoterpenes (camphor, 3-caren, limonene, myrcene, α-pinene, β-pinene, terpinolen, β-felandreene, p-cymol). The quantitative content of these resin acids depends on many factors (pine species, time and place of oleoresin collection, and sample collection and storage conditions). In addition, isomerization and oxidation reactions are observed, leading to a redistribution of the composition. In the studied oleoresins, the content of monoterpenes differs greatly, being the lowest in Alleps pine and the highest in Scots pine.
ESTABILIDADE E FOTOPROTEÇÃO DE FORMULAÇÕES CONTENDO EXTRATO DE PUNICA GRANATUM E METOXINAMATO DE OCTILA
Authors: Schettert Kerschner Karina , Batu de Souza Eduarda , Kessler Nunes Deuschle Viviane Cecilia 
Published: December 2021

A radiação ultravioleta provoca agressões na pele de forma cumulativa e irreversível e a fotoproteção continua sendo a forma mais eficaz de prevenção do câncer de pele e do fotoenvelhecimento. Muitos efeitos benéficos atribuídos às plantas medicinais e seus compostos bioativos tem sido alvo de estudos. Objetivo: desenvolver formulações cosméticas contendo o extrato comercial de P. granatum, acrescidas ou não de filtro solar orgânico sintético e avaliar a estabilidade e o Fator de Proteção Solar. Método: as formulações foram desenvolvidas contendo 1, 3 e 10 % do extrato de P. granatum, acrescidas ou não 7 % de metoxinamato de octila, em creme não iônico, e foi avaliada sua estabilidade físico-química, mediante a determinação das características organolépticas, pH e viscosidade. Também foi avaliada a espalhabilidade e o FPS in vito. Resultados: as formulações contendo somente o extrato de P. granatum foram as que apresentaram as maiores variações no estudo de estabilidade e o metoxinamato de octila parece interferir na estabilidade. Conclusão: conclui-se que a formulação contendo 10% do extrato de P. granatum e 7 % de metoxinamato de octila apresentou, além de estabilidade adequada, um incremento no FPS, o que proporcionaria uma redução dos filtros solares orgânicos em formulações de fotoprotetores. Recomenda-se que essa formulação seja conservada em temperatura ambiente e protegida da luz, calor e umidade.
O Elogio da Sedentarização na Viagem Contemporânea: Literatura, Pintura e Ecrã
Authors: Castro Maria João 
Published: December 2021

Se é verdade que a época em que nos encontramos é “a” época das viagens, não é menos exato que os turistas/viajantes se deslocam cada vez mais fechados frente ao ecrã do lar, viajando através dele. De facto, as novas tecnologias apenas permitem que nos “desloquemos” de outro modo ao interior de nós mesmos, não prejudicando a essência da viagem mas sim possibilitando uma outra forma de experienciar o mundo. Graças ao mundo em rede e à modernidade tecnológica, é hoje possível ver e “estar” em qualquer espaço do globo terrestre, ou seja, tornou-se quase impossível iniciar uma viagem até um ponto desconhecido e não catalogado. Então porque não abdicar da experiência material e, em vez disso, desfrutar da comodidade de viajar no sofá através do relato de outros, sem despender de dinheiro e padecimentos? Porque não tomar de empréstimo a odisseia dos que se deslocam e fazê-la nossa, personalizando-a? Mas ainda assim, alguém poderá dizer que a viagem não acontece? Este artigo pretende mergulhar no outro lado do espelho da viagem, na dinâmica de quem escolhe o elogio da sedentarização para viajar de uma “outra” forma. O viajante de “poltrona” dos tempos de Plínio, o Velho (século I) evoluiu até chegar à época contemporânea numa dinâmica transfronteiriça que se define a partir de um mundo paralelo mas não menos rico.
Linguagem, gênero e sexualidade na educação de jovens e adultos: uma proposta de multiletramentos críticos
Authors: Souza da Silva André Luiz , Silva da Rocha Dias Thayse , Bezerra Fábio Alexandre Silva 
Published: December 2021

Gênero e sexualidade na escola são temas conflituosos e permeados de percalços na prática pedagógica (MOITA LOPES, 2013). Contrário à crença popular, tratar desses assuntos não se resume a falar abertamente sobre práticas sexuais seguras ou sobre gravidez na adolescência, tampouco se trata de expor os estudantes a objetos ou aparatos que incitem à prática sexual. Com uma compreensão mais ampla sobre como questões de gênero e experiências sobre sexualidades diversas podem impactar no desenvolvimento saudável de alunos/as e de sua relação com a aprendizagem no espaço escolar, esta pesquisa, de natureza qualitativa e de caráter interpretativista, situada no âmbito da linguística aplicada indisciplinar (KLEIMAN, 2013; MOITA LOPES, 2006), analisa a recorrência da temática de gêneros e sexualidades nesse contexto e propõe possibilidades de como abordá-la em sala de aula, a partir de práticas de multiletramentos (COPE; KALANTZIS, 2015; ROJO, 2012), nas aulas de língua portuguesa da Educação de Jovens e Adultos (EJA) mediante práticas de leitura, análise linguística e escrita guiadas pela Proposta Curricular para a Educação de Jovens e Adultos (BRASIL, 2002). Para tanto, objetiva-se: 1) identificar e discutir quais itens linguísticos têm sido utilizados no contexto escolar para se referir às identidades de gênero e sexualidades, e 2) apresentar uma proposta de ensino que contemple a temática proposta com base nas funcionalidades da linguagem (ANTUNES, 2009; BAGNO, 2009). Resultados gerais indicam a necessidade de uma abordagem de identidades de gênero e de sexualidades no contexto escolar que desafie visões essencialistas dos indivíduos e promova uma atitude de respeito à diversidade frente aos desafios que a sociedade contemporânea nos apresenta para além dos muros da escola.
O processo de reescrituração da palavra “muro” em textos jornalístico de revista “Veja”
Authors: Carneiro Lemes Renata , Mahmudo Karim Taisir 
Published: December 2021

O presente artigo tem como objetivo, sob a ótica da semântica do acontecimento, analisar o processo de reescrituração da palavra muro , em outras palavras, o modo como a referida palavra ao se repetir produz um novo significado. Para isso, a analise constituirá de quatro textos jornalísticos da revista Veja publicados nos anos 2014, 2015 e 2017, que tematizam sobre a palavra muro na relação com outros sentidos que rememoram um passado enunciativo, no presente do acontecimento. A base teórica e metodológica está fundamentada em conceitos da teoria da semântica do acontecimento, conforme proposta por Guimarães (2002, 2004 e 2005). Assim, analisaremos o modo como o processo de reescrituração se constitui em textos jornalísticos que tematizam o “muro” enquanto acontecimento enunciativo, de modo que o locutor-jornalista, ao enunciar, é afetado por seu lugar social no acontecimento enunciativo. Tudo isso nos fez observar o processo de significação de outro(s) sentido(s) da palavra muro pelo efeito da repetição nos textos jornalísticos.
Antioxidant, Antimicrobial, and Molecular Docking Studies of Novel
Chalcones and Schiff Bases Bearing 1, 4-naphthoquinone Moiety
Authors: Elkanzi Nadia Ali Ahmed , Hrichi Hajer , Bakr Rania B. 
Published: December 2021

Background:
The 1,4-naphthoquinone ring has attracted prominent interest in the field of medicinal
chemistry due to its potent pharmacological activities such as antioxidant, antibacterial, antifungal,
and anticancer.

Objective:
Herein, a series of new Schiff bases (4-6) and chalcones (8a-c & 9a-d) bearing 1,4-
naphthoquinone moiety were synthesized in good yields and were subjected to in-vitro antimicrobial,
antioxidant, and molecular docking testing.

Methods:
A facile protocol has been described in this study for the synthesis of new derivatives (4-7, 8ac,
and 9a-d) bearing 1,4-naphthoquinone moiety. The chemical structures of all the synthesized compounds
were identified by 1H-NMR, 13C-NMR, MS, and elemental analyses. Moreover, these derivatives
were assessed for their in-vitro antimicrobial activity against gram-positive, gram-negative bacteria, and
fungal strains. Further studies were conducted to test their antioxidant activity using DPPH (2,2-diphenyl-
1-picrylhydrazyl) scavenging assay. Molecular docking studies were realized to identify the most likely
interactions of the novel compounds within the protein receptor.

Results:
The antimicrobial results showed that most of the compounds displayed good efficacy against
both bacterial and fungal strains. The antioxidant study revealed that compounds 9d, 9a, 9b, 8c, and 6
exhibited the highest radical scavenging activity. Docking studies of the most active antimicrobial compounds
within GLN- 6-P, recorded good scores with several binding interactions with the active sites.

Conclusion:
Based on the obtained results, it was found that compounds 8b, 9b, and 9c displayed the
highest activity against both bacterial and fungal strains. The obtained findings from the DPPH radical
scavenging method revealed that compounds 9d and 9a exhibited the strongest scavenging potential. The
molecular docking studies proved that the most active antimicrobial compounds 8b, 9b and 9c displayed
the highest energy binding scores within the glucosamine-6-phosphate synthase (GlcN-6-P) active site.
Calcium Modification Therapies in Contemporary Percutaneous Coronary
Intervention
Authors: Zaidan Mohammad , Alkhalil Mohammad , Alaswad Khaldoon 
Published: December 2021

Abstract:
Coronary artery calcifications (CAC) has been known to be associated with worse Percutaneous Coronary Intervention (PCI) short- and long-term outcomes. Nowadays with the increased prevalence of the risk factors leading to CAC in the population and also more PCI procedures done in older patients and with the growing number of higher risk cases of chronic total occlusion (CTO) PCI and PCI after coronary artery bypass grafting(CABG), severe cases of CAC are now encountered on a daily basis in the catheterization lab and remain a big challenge to the interventional community, making it crucial to identify cases of severe CAC and plan a CAC PCI modification strategy upfront. Improved CAC detection with intravascular imaging helped identifying more of these severe CAC cases and predicting response to therapy and stent expansion based on CAC distribution in the vessel. Multiple available therapies for CAC modification has evolved over the years, familiarity with the specifics and special considerations and limitations of each of these tools is essential in the choice and application of these therapies when used in severe CAC treatment.
In this review we discuss CAC pathophysiology, modes of detection, and different available therapies for CAC modification.