bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multisite Seasonal Monitoring of Pecan Aphids and Their Parasitoid in Commercial Pecan Orchards
Authors: Slusher Eddie K , Hudson William G , Halliday Pamela L , Acebes-Doria Angelita L 
Published: June 2021

Abstract
Aphids are important pests of pecans in Georgia. Although previous studies conducted seasonal monitoring of pecan aphids, these studies were done at a single experimental site. In addition, only a few seasonal monitoring studies have tracked pecan aphid mummies parasitized by the aphid parasitoid, Aphelinus perpallidus Gahan. The objective of this study was to assess the seasonal phenology of yellow pecan aphid (Monelliopsis pecanis Bissell), blackmargined aphid [Monellia caryella (Fitch)], black pecan aphid [Melanocallis caryaefoliae (Davis)], aphid mummies, and adult A. perpallidus in four Georgia commercial orchards, with varying aphid management regimes, in 2019 and 2020. Comparison of overall aphid and parasitoid numbers between sites revealed few consistent annual patterns in both years. Aphid seasonal trends were consistent among sites and followed the patterns seen in previous studies, with the yellow aphid complex peaking in May, June, September, and October and black pecan aphids peaking in late September and October. Despite varying levels of insecticide application between sites, aphid phenology followed a similar seasonal pattern and remained low, throughout both growing seasons. This may indicate that growers can apply low frequencies of insecticides and still achieve pecan aphid control. Parasitism numbers were highest in the low insecticide frequency site compared with the other three sites. Mummies varied in their correlation with yellow aphid complex and black pecan aphid numbers. Parasitoid numbers typically followed the cycle of their host throughout the season.
Diversity and Parasitism by Parasitic Wasps That AttackDalbulus maidis(Hemiptera: Cicadellidae) on Year-Round and Seasonal Maize Agroecosystems
Authors: Torres-Moreno Rosaura , Moya-Raygoza Gustavo 
Published: June 2021

AbstractAgroecosystems undergo frequent anthropogenic disturbance that may affect the diversity, community, and abundance of natural enemies living there. In the tropics, annual crops such as maize are planted two times (year-round crops) or one time (seasonal crops) per year. Little is known about how natural enemies of insect pests respond to maize agroecosystems planted one vs. two times during each annual cycle. The objective was to investigate the diversity and parasitism of egg parasitoids of the pest Dalbulus maidis (DeLong) (Hemiptera: Cicadellidae) in maize agroecosystems planted year-round and seasonally. Potted maize plants with D. maidis eggs were placed within these two maize agroecosystems to attract egg parasitoids during the maize-growing wet season in Mexico. In these two maize agroecosystems, similar levels of diversity were found, using the Shannon-Wiener index (H′). Communities of parasitic wasps were found attacking the eggs of D. maidis in both maize agroecosystems, but there were differences in the composition of these communities. In the year-round maize agroecosystem, Paracentrobia sp. near subflava (Girault) (Hymenoptera: Trichogrammatidae) was the most common, while Anagrus virlai Triapitsyn (Hymenoptera: Mymaridae) was most common in the seasonal maize. A greater total abundance and total rate of parasitoid emergence were found in the year-round maize agroecosystem compared with the seasonal maize. In addition, a positive relationship between the number of D. maidis eggs and parasitoid abundance was found in both maize agroecosystems. However, a negative density dependence between the number of D. maidis eggs and the percentage of parasitism was found in both maize agroecosystems.
Assessment of Physical Activity in Adults Using Wrist Accelerometers
Authors: Liu Fangyu , Wanigatunga Amal A , Schrack Jennifer A 
Published: June 2021

Abstract
The health benefits of physical activity (PA) have been widely recognized, yet traditional measures of PA, including questionnaires and category-based assessments of volume and intensity, provide only broad estimates of daily activities. Accelerometers have advanced epidemiologic research on PA by providing objective and continuous measurement of PA in free-living conditions. Wrist-worn accelerometers have become especially popular because of low participant burden. However, the validity and reliability of wrist-worn devices for adults have yet to be summarized. Moreover, accelerometer data provide rich information on how PA is accumulated throughout the day, but only a small portion of these rich data have been used by researchers. Last, new methodological developments are emerging that aim to overcome some of the limitations of accelerometers. In this review, we provide an overview of accelerometry research, with a special focus on wrist-worn accelerometers. We describe briefly how accelerometers work; summarize the validity and reliability of wrist-worn accelerometers; discuss the benefits of accelerometers, including measuring light-intensity PA; and discuss pattern metrics of daily PA recently introduced in the literature. A summary of large-scale cohort studies and randomized trials that implemented wrist-worn accelerometry is provided. We conclude the review by discussing new developments and directions of research using accelerometers, with a focus on wrist-worn accelerometers.
Human Agency in Educational Trajectories: Evidence from a Stratified System
Authors: Burger Kaspar 
Published: June 2021

AbstractIn the research on life-course outcomes, there is a long-standing debate on the relative importance of institutional structure and human agency. This study examines how structure and agency influence educational trajectories in Switzerland. The Swiss education system is hierarchically differentiated but permeable, providing both standard and non-standard pathways to higher education. Using data from a 15-year panel survey, the study assesses, first, the extent to which lower-secondary-school track attendance is associated with individuals’ probability of moving into an academic or vocational programme at upper-secondary level and, second, how this predicts the probability of subsequently entering a university. The study also examines how human agency influences these probabilities. Results of a structural equation model show that lower-secondary track attendance significantly predicts individuals’ probability of transitioning into academic education, whereas human agency plays a minor, albeit non-negligible, role in this regard. In turn, pursuing an academic rather than a vocational programme is associated with a 47-percentage point (or 16-fold) higher probability of subsequently attending university. Individuals comparatively rarely follow non-standard pathways to university, irrespective of their level of agency. The education system channels educational trajectories, but the power of the channelling effect varies across the different junctures of the system.
Why Do Lower Educated People Separate More Often? Life Strains and the Gradient in Union Dissolution
Authors: Hogendoorn Bram , Kalmijn Matthijs , Leopold Thomas 
Published: June 2021

Abstract
In many Western countries, coresidential unions of lower educated people are less stable than those of higher educated people. A prominent explanation of this gradient in union dissolution holds that the lower educated experience more strain. Evidence for this explanation has been limited by a focus on only the economic dimension of strain and on only one partner in each union. In this study, we broadened the concept of strain to cover multiple life domains and capture the experience of both partners in each union. To do so, we used longitudinal data from the Household, Income and Labour Dynamics in Australia survey (N = 52,574 union-years; 7,930 unions). Generalized structural equation models showed that lower educated individuals experienced more strain not only in the economic domain but also in other life domains. Moreover, lower educated individuals tended to have partners who experienced more strain as well. In total, the joint experience of life strains explained 49% of the education gradient in union dissolution. These results suggest that life strains are pivotal to the stratification of family life.
Health-related quality of life associated with nocturnal leg cramps in primary care: a mixed methods study
Authors: Sebo Paul , Haller Dagmar M , Kaiser Céline , Zaim Armita , Heimer Olivier , Chauveau Nicolas , Maisonneuve Hubert 
Published: June 2021

Abstract

Background
Although nocturnal leg cramps are common, little research is available about their impact on quality of life. This mixed-methods study explored the impact of nocturnal leg cramps on health-related quality of life (HRQoL).

Methods
The study included primary care patients (&gt;50 years) who reported suffering from nocturnal leg cramps (2016–2017). In the quantitative phase, patients completed a questionnaire about their HRQoL (SF-36) and the frequency of their cramps, and we computed the SF-36 scores. Then, we conducted a qualitative study using semi-structured interviews with patients with various levels of HRQol to explore their perception of the impact of cramps on their lives.

Results
A total of 114 patients (49%) agreed to participate in the quantitative study (mean age: 71, women: 62%) and 15 patients were included in the qualitative study (mean age: 69, women: 67%). The number of cramps in the previous week was low (mean: 1.6 (SD 1.5)). The SF-36 mean physical and mental summary scores were 43 and 50, respectively, and the domain scores were similar to a comparative general population. Whilst some patients reported little interference with their daily lives, others reported a major decrease in their HRQoL. SF-36 scores were not sufficient to describe the cramp-related impairment, as patients from all levels of SF-36 scores reported major impacts of NLC in the interviews.

Conclusions
Some patients describe a specific impact of cramps on their lives, regardless of their HRQoL. These patients should be the target of future intervention trials.
Using Theories of Behavior Change to Develop Interventions for Healthy Aging
Authors: Klusmann Verena , Gow Alan J , Robert Philippe , Oettingen Gabriele 
Published: June 2021

Abstract
Healthy aging requires people to adopt and maintain beneficial behaviors in all stages of the life span. Supporting behavior change, including via the motivation to make and maintain those changes, is therefore important for the promotion of healthy aging. The aim of this overview is to introduce theoretical frameworks from the psychology of motivation that lend themselves to the development of effective interventions promoting behavior change conducive to healthy aging. We discuss theoretical frameworks referring to the determinants, properties, and functionality of goals aimed at behavior change, and consider the implications of the various theories for designing interventions to support healthy aging. We first consider theories that focus on beliefs and attitudes as determinants of goals, then we address theories that focus on the structure and content as important properties of goals, and, finally, we examine theories drawing on conscious and nonconscious processes underlying the functionality of these goals. We will present if–then planning and mental contrasting, as well as nudging and boosting, that is, novel strategies of behavior change that support the creation of scalable interventions for healthy aging across the life span. Against this background, new perspectives emerge for modern, state-of-the-art, and individually tailored interventions with the aim of enhancing older people’s healthy living.
Care Recipient Controlling and Manipulative Behavior and Caregiver Depressive Symptoms: The Role of Race, Caregiver Resentment, and Mutual Communal Behavior
Authors: Johnson Michelle R , Lance Charles E , Williamson Gail M 
Published: June 2021

Abstract

Background and Objectives
We explored whether relationship quality, as measured by mutual communal behavior, would serve as a buffer against caregiver resentment and, consequently, depressive symptoms when care recipients (CRs) engage in problem behavior (i.e., controlling and manipulative behavior [CMB]). Using the common core model of caregiver distress, we hypothesized that caregiver resentment would explain why caregivers were depressed when their CRs engage in CMB. We predicted that the indirect effect of CRCMB on depressive symptoms via resentment would depend on the strength of the communal bond between the caregiver and CR. Resentment was expected to play a significant role in explaining the association between CRCMB and depressive symptoms for caregivers in less communal relationships, but a small or nonexistent role for those in highly communal relationships. We also investigated whether these effects were different for Black and White caregivers.

Research Design and Methods
Data were obtained from 187 Black and 247 White caregivers from the second Family Relationships in Late Life Project. Before testing our model, we confirmed the measurement equivalence/invariance of the four scales used in this study.

Results
Resentment mediated the association between CRCMB and depressive symptoms. However, the indirect effect was larger among highly communal caregivers. Caregiver race did not moderate the moderated mediation.

Discussion and Implications
The communal bond between the caregiver and CR does not entirely protect the caregiver from depressive symptoms, particularly among highly communal caregivers. Interventions aimed at improving caregiver outcomes should acknowledge the unique vulnerabilities of caregivers in close relationships.
Isostasy with Love: II Airy compensation arising from viscoelastic relaxation
Authors: Beuthe Mikael 
Published: June 2021

SUMMARYIn modern geodynamics, isostasy can be viewed either as the static equilibrium of the crust that minimizes deviatoric stresses, or as a dynamic process resulting from the viscous relaxation of the non-hydrostatic crustal shape. Paper I gave a general formulation of Airy isostasy as an elastic loading problem solved with Love numbers, and applied it to the case of minimum stress isostasy. In this sequel, the same framework is used to study Airy isostasy as the long-time evolution of a viscoelastic shell submitted to surface and internal loads. Isostatic ratios are defined in terms of time-dependent deviatoric Love numbers. Dynamic isostasy depends on the loading history, two examples of which are the constant load applied on the surface in the far past and the constant shape maintained by addition or removal of material at the compensation depth. The former model results in a shape decreasing exponentially with time and has no elastic analogue, whereas the latter (stationary) model is equivalent to a form of elastic isostasy. Viscoelastic and viscous approaches are completely equivalent. If both load and shape vary slowly with time, isostatic ratios look like those of the stationary model. Isostatic models thus belong to two independent groups: the elastic/stationary approaches and the time-dependent approaches. If the shell is homogeneous, all models predict a similar compensation of large-scale gravity perturbations. If the shell rheology depends on depth, stationary models predict more compensation at long wavelengths, whereas time-dependent models result in negligible compensation. Mathematica and Fortran codes are available for computing the isostatic ratios of an incompressible body with three homogeneous layers.
Reproductive Violence as a Category of Analysis: Disentangling the Relationship between ‘the Sexual’ and ‘the Reproductive’ in Transitional Justice
Authors: Laverty Ciara , de Vos Dieneke 
Published: June 2021

Abstract
There has been limited engagement with reproductive violence in the field of transitional justice. Highlighting how, where this has taken place, reproductive violence has tended to be approached through the lens of sexual violence, this article problematises the category of ‘the sexual’ in understanding conflict-related violence. Advancing an approach to reproductive violence that centralises the notions of reproductive autonomy and choice, along with recognition of the structural conditions within which they can be exercised, the article argues that placing acts of reproductive violence within a frame of ‘sexual violence’ obscures the complexities of harm inflicted on women and masks the distinct gendered structures that underpin different forms of violence. The article ultimately argues that conceptualising reproductive violence in this way can contribute to greater understanding within transitional justice of the diverse harms experienced by women and has the potential to challenge the gendered normalisation of control over their reproductive functions.
Prevalence of Human Papillomavirus Among Women Older than Recommended Age for Vaccination by Birth Cohort, United States 2003‒2016
Authors: Vahle Kristin , Gargano Julia W , Lewis Rayleen M , Querec Troy D , Unger Elizabeth R , Bednarczyk Robert A , Markowitz Lauri E 
Published: June 2021

Abstract

Background
Apparent associations between human papillomavirus (HPV) prevalence and age observed in cross-sectional studies could be misleading if cohort effects influence HPV detection.

Methods
Using data from 2003–2016 National Health and Nutrition Examination Surveys, we evaluated overall and 10-year birth cohort-specific cervicovaginal HPV prevalence estimates (any, high-risk [HR], and non-HR) by 3-year age group among 27 to 59-year-old women born in 1950–1979. Average percent changes (APC) in HPV prevalence by 3-year age were calculated.

Results
Overall, prevalence of any HPV declined from 49.9% in 27–29 year olds to 33.8% in 57–59 year olds (APC, −2.82% per 3-year age group; 95% confidence interval [CI], −4.02% to −1.60%) as did prevalence of HR-HPV (APC, −6.19%; 95% CI, −8.09% to −4.26%) and non–HR-HPV (APC, −2.00%; 95% CI, −3.48% to −.51%). By birth cohort, declines by age group were seen in prevalences of any HPV, HR-HPV, and non–HR-HPV for those born in the 1950s and 1970s and in any HPV and HR-HPV for those born in the 1960s (APC range, −14.08% to 0.06%).

Conclusions
Declines in HPV prevalence with age in these cross-sectional surveys cannot be explained by birth cohort differences alone, as associations were observed across all birth cohorts.
HIV-1 RNA Kinetics in Blood Plasma and in Seminal Plasma of Men Starting a Dolutegravir-Based Triple-Combination Regimen at the Time of Primary HIV-1 Infection
Authors: Ghosn Jade , Assoumou Lambert , Lascoux-Combe Caroline , Peytavin Gilles , Amat Karine , Gabassi Audrey , Le Minh P , Nzalakanda Robert , Valin Nadia , Landman Roland , Chaix Marie-Laure , Delaugerre Constance 
Published: June 2021

Abstract
We compared the proportion of participants achieving first undetectable HIV-1 RNA (VL) in seminal plasma (SP) and blood plasma (BP) in 19 men starting dolutegravir-based regimen at primary HIV infection. At baseline, median VL was 6.5 (interquartile range [IQR], 5.6–7.9) and 4.5 (IQR, 3.5–5.0) log10 copies/mL in BP and SP, respectively. Between baseline and week 48, significantly higher proportion of participants achieved first VL below limit of quantification in SP (93.0%) than in BP (84.2%; P = .008). Time to first undetectable VL was 8 weeks in SP (95% confidence interval [CI], 5.6–10.4) and 24 weeks in BP (95% CI, 14.1–33.9).
Longitudinal Changes in Epigenetic Age Acceleration in Aviremic Human Immunodeficiency Virus–Infected Recipients of Long-term Antiretroviral Treatment
Authors: Esteban-Cantos Andrés , Montejano Rocio , Rodríguez-Centeno Javier , Saiz-Medrano Gabriel , De Miguel Rosa , Barruz Pilar , Bernardino Jose I , Mena-Garay Beatriz , Cadiñanos Julen , Jiménez-González María , Nevado Julián , Valencia Eulalia , Mayoral-Muñoz Mario , Arribas Jose R , Rodés Berta 
Published: June 2021

Abstract

Background
Human immunodeficiency virus (HIV) infection induces epigenetic age acceleration (EAA), but it remains unclear whether epigenetic aging continues to accelerate during successful antiretroviral therapy (ART) and prolonged virological suppression.

Methods
We longitudinally analyzed 63 long-term aviremic HIV-infected adults. Using blood DNA methylation patterns, we calculated EAA measures based on 3 epigenetic clocks (Horvath’s clock, PhenoAge, and GrimAge). We recorded the emergence of serious AIDS-related and non-AIDS-related events throughout the study to assess its association with EAA.

Results
All participants were on stable ART and were virologically suppressed. After 4 years of follow-up, PhenoAge-EAA and GrimAge-EAA showed no differences, whereas Horvath-EAA slightly decreased (median difference, –0.53 years; P = .015). Longitudinal changes in EAA measures were independent of changes in CD4 cell counts, the ART regimen, or other HIV-related factors. Nineteen percent of participants experienced a serious clinical event during the study. Horvath-EAA was significantly higher at baseline in participants with clinical events (P = .027). After adjusting for confounders, we found a trend toward an association of higher levels of all EAA measures at baseline with serious clinical events.

Conclusions
Epigenetic aging did not accelerate in long-term aviremic HIV-infected adults after 4 years of successful ART. EAA measures deserve further study as potential tools for predicting clinical events.
Interchangeability of periplasmic adaptor proteins AcrA and AcrE in forming functional efflux pumps with AcrD in Salmonella enterica serovar Typhimurium
Authors: Alav Ilyas , Bavro Vassiliy N , Blair Jessica M A 
Published: June 2021

Abstract

Background
Resistance-nodulation-division (RND) efflux pumps are important mediators of antibiotic resistance. RND pumps, including the principal multidrug efflux pump AcrAB-TolC in Salmonella, are tripartite systems with an inner membrane RND transporter, a periplasmic adaptor protein (PAP) and an outer membrane factor (OMF). We previously identified the residues required for binding between the PAP AcrA and the RND transporter AcrB and have demonstrated that PAPs can function with non-cognate transporters. AcrE and AcrD/AcrF are homologues of AcrA and AcrB, respectively. Here, we show that AcrE can interact with AcrD, which does not possess its own PAP, and establish that the residues previously identified in AcrB binding are also involved in AcrD binding.

Methods
The acrD and acrE genes were expressed in a strain lacking acrABDEF (Δ3RND). PAP residues involved in promiscuous interactions were predicted based on previously defined PAP-RND interactions and corresponding mutations generated in acrA and acrE. Antimicrobial susceptibility of the mutant strains was determined.

Results
Co-expression of acrD and acrE significantly decreased susceptibility of the Δ3RND strain to AcrD substrates, showing that AcrE can form a functional complex with AcrD. The substrate profile of Salmonella AcrD differed from that of Escherichia coli AcrD. Mutations targeting the previously defined PAP-RND interaction sites in AcrA/AcrE impaired efflux of AcrD-dependent substrates.

Conclusions
These data indicate that AcrE forms an efflux-competent pump with AcrD and thus presents an alternative PAP for this pump. Mutagenesis of the conserved RND binding sites validates the interchangeability of AcrA and AcrE, highlighting them as potential drug targets for efflux inhibition.