bluuebunny/crossref_metadata_2025_split huggingface dataset:
Features of a Booming Reproductive Practice: The Medical Process, the Market, the Antecedents, and the Risks
Authors: Bandelli Daniela 
Published: October 2021

AbstractSurrogacy is a social practice aimed at the procreation of human beings through the use of biomedical technologies. It includes the willingness of a woman to carry out a pregnancy and give birth to a child, with whom she has no genetic link, which will be immediately entrusted at birth to the people who wanted and commissioned it, known as the intended parents. A multi-million transnational market has flourished around this kind of arrangement, with the national legal frameworks being very different from each other and constantly changing. The surrogate’s revenue varies considerably from country to country, as does the price that the aspiring parents pay. This chapter aims to introduce readers to the topic by providing the main coordinates of the phenomenon: how the medical-procreative procedure takes place, what the commercial transaction consists of; the history of this market, the similarity of surrogacy with other procreative practices, and the difference with other assisted procreation practices; the variety of regulatory frameworks, the flexibility of the market according to the logic of globalization; the health risks and the inevitability for the child of the fracture with the “environment” in which he began his psychophysical development.
Sociological Perspectives Across Individual Experiences, Social Structures, and Representations
Authors: Bandelli Daniela 
Published: October 2021

AbstractThis chapter is a literature review which aims to highlight the most critical aspects discussed in the surrogacy scholarship, whose interdisciplinarity represents a major value for the advancement of the sociological understanding of the phenomenon. The literature review is organized into three levels. The first is that of individual experience, which includes some of the main ethnographies that have tried to explain the motivations that push people, aspiring parents but above all the surrogates, to undertake this procreative path. At the second level, that of the social structure, there are three recurring themes: inequality—explained through the concept of stratified reproduction—which permeates the relationships between the parties and upon which the surrogacy market proliferates; the transformation of procreation into a productive process in which life is commodified and the woman reduced to her womb; the transformation of kinship from a natural fact to a cultural product, which is defined by one’s own intentions, and the parallel fragmentation of motherhood into several figures. At the third level, that of representation, there are the studies that discuss how surrogacy is told by the media, and the studies that provide a systematization of the different feminist perspectives on the subject.
The Italian Case: A Strong Opposition in the Name of Women’s Sexual Identity and Motherhood
Authors: Bandelli Daniela 
Published: October 2021

AbstractSurrogacy is prohibited by law in Italy but it is increasingly undergone abroad by Italian aspiring parents. Although the majority of couples resorting to surrogacy internationally are heterosexuals, the surrogacy debate in Italy intertwines with discussions on homo-parenting and the problem of children born through surrogacy abroad, remaining in a legal limbo once they arrive in Italy. Since 2015, Italian feminists, led by the feminist group Senonoraquando-Libere (Snoq-L), in alliance with French feminists, have mobilized for the universal ban of surrogacy and the enforcement of surrogacy national prohibition, along with saying no to attempts of legalization promoted by same-sex families and civil rights organizations. Italian feminists are engaging in a battle that presently, and until surrogacy will be prohibited by law, does not closely pertain to the exploitation or commodification of women in the country, but to the commodification of women in other countries of the world, and more broadly to the theoretical notion of “the woman”. Although there are other feminists who do not agree with the abolitionist demand, this case study does not identify a structured regulatory or pro-surrogacy feminist front.
Conclusions
Authors: Bandelli Daniela 
Published: October 2021

AbstractThis conclusive chapter offers a few proposals to contribute to the necessary overcoming of the current polarization in the debate: adult-centric arguments could be renovated by focusing on the child as the protagonist of reproduction and representative of tomorrow’s humanity; adult participation in surrogacy could be understood as the result of decision-making influenced by social values of self-determination, with any support or condemnation of surrogacy being grounded on considerations about the social impact of surrogacy and child’s protection and not on the immediate personal benefits that it gives to the adults; the ideal goal of eliminating surrogacy can coexist with pragmatic restrictive regulatory initiatives; monitoring both the surrogates and children’s health and well-being, along with the quantification of surrogacy births are priority objectives to be achieved regardless of prohibitionist or regulatory orientations; inform women who are targets of recruitment about medical and legal risks and individual as well as social implications of surrogacy for their life and for children; single issue campaigns focused on the child and woman’s health can offer platforms of dialogue and mobilization for social movements which on other themes (e.g. abortion, same-sex couples parenting, and women empowerment) have different and even opposing views.
Coherence, Alignment and Integration: Understanding the Legal Relationship Between Sustainable Development, Climate Change Adaptation and Disaster Risk Reduction
Authors: Cubie Dug , Natoli Tommaso 
Published: October 2021

AbstractInternational law can play an important role in promoting national, regional and international actions to tackle the human impacts of climate change and disasters. Of note, 2015 saw the adoption of three interconnected normative frameworks: the Sendai Framework for Disaster Risk Reduction 2015–2030, the Paris Agreement under the UN Framework Convention on Climate Change (UNFCCC), and the UN’s 2030 Agenda for Sustainable Development and the Sustainable Development Goals (SDGs). One may therefore be tempted to view this body of international norms, rules and standards as a comprehensive and unified system. Yet the increasing complexity and specialisation of different international legal regimes has led to concerns regarding a confusing fragmentation of international law. This chapter will therefore examine the relationship between the three topics of sustainable development, climate change adaptation (CCA) and disaster risk reduction (DRR) from a legal perspective. The chapter will commence with a discussion of the legal status of different international instruments, before providing a textual analysis of the language used by states, the UN, NGOs and other actors in the relevant documents. We then propose an ‘hourglass’ model of the legal relationships between these three different international frameworks based on: systemic coherence at the international level; vertical alignment between the international, regional and national levels; and horizontal integration of international norms at the domestic level. To support this proposal, examples will be provided from the Pacific Island Countries (PICs), drawing on research undertaken through the IRC-MSCA CAROLINE project ‘Leave No One Behind: Developing Climate-Smart/Disaster Risk Management Laws that Protect People in Vulnerable Situations for a Comprehensive Implementation of the UN Agenda 2030.’
Bridging Gaps: Connecting Climate Change Risk Assessments with Disaster Risk Reduction and Climate Change Adaptation Agendas
Authors: Paterson Shona K. , Guida Kristen 
Published: October 2021

AbstractChanging climates and increasing variability, in combination with maladaptive societal responses, present many threats and risks to both social and biophysical systems. The outcomes of such changes will progressively affect all aspects of ecosystem functioning including social, political, and economic landscapes. Coordination between the three frameworks that govern risk at national and subnational scales, climate change risk assessments, climate adaptation planning and disaster risk reduction (DRR), is often lacking or limited. This has resulted in a siloed and fragmented approach to climate action. By examining risk as a dynamic social construction that is reimagined and reinvented by society over time, this chapter explores how a greater degree of cohesion between these three frameworks might be achieved.
Enhancing Integration of Disaster Risk and Climate Change Adaptation into Irish Emergency Planning
Authors: Medway Peter , Flood Stephen , Cubie Dug , Le Tissier Martin 
Published: October 2021

AbstractThis chapter critically assesses the integration of climate change adaptation and disaster risk reduction with a special focus on the Irish policy and governance context. The chapter first presents a comprehensive overview of the Irish policy environment for climate change adaptation and disaster risk reduction including its current level of integration. Analysis of alignment with global and regional drivers of integration is then considered. Next, drawing on empirical research conducted with multidisciplinary experts across the Republic of Ireland, the chapter employs the SHIELD model, developed by the EU-funded ESPREssO project, which outlines six pathways to enhance integration across the domains of climate change adaptation and disaster risk reduction. The pathways comprise of sharing knowledge, harmonising capacities, institutionalising coordination, engaging stakeholders, leveraging investments and developing communication. Findings of stakeholder focus groups and survey responses highlight the challenges and opportunities for impactful integration between climate change adaptation and disaster risk reduction in Ireland from a practitioner perspective across the six SHIELD pathways. Finally, conclusions from the study indicate the importance of governance, management and coordination of systems for climate change adaptation and disaster risk reduction; the sequencing of policy-making, planning and research; and the significance of specificity in relation to use of the six SHIELD pathways.
Mainstreaming Climate Change Adaptation into Planning and Development: A Case Study in Northern Ireland
Authors: Burns Cathy , Flood Stephen , O’Dwyer Barry 
Published: October 2021

AbstractThis study outlines the adaptation planning journey undertaken by Derry City and Strabane District Council (DCSDC) in Northern Ireland and reflects how the prevailing policy context and level of organisational adaptive capacity create the conditions for mainstreaming climate adaptation into planning and development. This chapter explores the potential of local government in Northern Ireland to integrate local authority policy drivers such as disaster risk reduction (DRR), emergency planning, risk and assurance, and community resilience. The ability to communicate risks and solutions was identified as an important consideration when undertaking adaptation planning, particularly when discussing the adaptation planning process and securing input or support from colleagues. Moreover, a significant amount of engagement was required with local government agencies to increase understanding of the relevance of climate change and DRR. Embedding DRR and climate change adaptation (CCA) within local authority policy and planning can enable a greater understanding of specific risks to local governments and act as a catalyst for further action.
Sustainability, Disaster Risk Reduction and Climate Change Adaptation: Building from the Bottom Up – A South African Perspective from the Small-scale Fisheries Sector
Authors: Sowman Merle , Rebelo Xavier 
Published: October 2021

AbstractThis chapter explores the vulnerability context of coastal fishing communities, including the various factors that shape their capacity to cope with and adapt in the face of poverty and increasing threats associated with climate change and natural and human-induced disasters through the lens of small-scale fisheries (SSFs) in South Africa. South Africa has developed a suite of policies, strategies and laws to deal with commitments to sustainable development and address and manage climate change challenges and disaster risks. These national policies, however, are not well aligned or implemented in a coordinated and integrated manner. Nor are they attuned to the realities facing local communities. This chapter reports on work in coastal communities in South Africa that reveals the lack of policy alignment and limited coordination across government departments at all levels charged with oversight responsibilities for these endeavours. Findings suggest that incorporating local knowledge into local development and sector plans, as well as into sustainable development and sector-specific policies, strategies and plans at the national level, would enhance understanding of the realities on the ground and lead to policies, strategies and plans that are more harmonised and more likely to be supported and implemented. How this knowledge gets integrated both vertically and horizontally into formal government planning and decision-making processes, however, and leads to implementation of projects and plans that yield tangible results, remains a challenge.
Adapting to Climate Change Through Disaster Risk Reduction in the Caribbean: Lessons from the Global South in Tackling the Sustainable Development Goals
Authors: Jerez Columbié Yairen 
Published: October 2021

AbstractDeveloping resilience in conditions of extreme geographic and economic vulnerability, Small Island Developing States (SIDS) have learned to share what works for adaptation on the ground through transnational Disaster Risk Reduction initiatives that address the Sustainable Development Goals (SDGs). This chapter focuses on South-South Cooperation between Caribbean SIDS on Climate Change Adaptation and Disaster Risk Management, as well as triangulation with the European Union and international organisations through the African, Caribbean and Pacific-European Union Natural Disaster Risk Reduction (ACP-EU NDRR) Program. It critically analyses collaborations between regional platforms to show evidence of successful transferable adaptation strategies and tools that have emerged from disaster risk management experiences. Acknowledging the SIDS’ contribution to climate change adaptation is key for advancing both research and action. The examples of South-South cooperation between SIDS and triangulation with Europe and international organisations addressed in this chapter show that a coherent and effective theoretical framework for impactful adaptation research and global climate action should bring forward participatory, transdisciplinary and translocal perspectives informed by the experiences of early adaptors in the Global South.
Prediabetes and risk of mortality, diabetes-related complications and comorbidities: umbrella review of meta-analyses of prospective studies
Authors: Schlesinger Sabrina , Neuenschwander Manuela , Barbaresko Janett , Lang Alexander , Maalmi Haifa , Rathmann Wolfgang , Roden Michael , Herder Christian 
Published: October 2021

Abstract
Aims/hypothesis
The term prediabetes is used for individuals who have impaired glucose metabolism whose glucose or HbA1c levels are not yet high enough to be diagnosed as diabetes. Prediabetes may already be associated with an increased risk of chronic ‘diabetes-related’ complications. This umbrella review aimed to provide a systematic overview of the available evidence from meta-analyses of prospective observational studies on the associations between prediabetes and incident diabetes-related complications in adults and to evaluate their strength and certainty.

Methods
For this umbrella review, systematic reviews with meta-analyses reporting summary risk estimates for the associations between prediabetes (based on fasting or 2 h postload glucose or on HbA1c) and incidence of diabetes-related complications, comorbidities and mortality risk were included. PubMed, Web of Science, the Cochrane Library and Epistemonikos were searched up to 17 June 2021. Summary risk estimates were recalculated using a random effects model. The certainty of evidence was evaluated by applying the GRADE tool. This study is registered with PROSPERO, CRD42020153227.

Results
Ninety-five meta-analyses from 16 publications were identified. In the general population, prediabetes was associated with a 6–101% increased risk for all-cause mortality and the incidence of cardiovascular outcomes, CHD, stroke, heart failure, atrial fibrillation and chronic kidney disease, as well as total cancer, total liver cancer, hepatocellular carcinoma, breast cancer and all-cause dementia with moderate certainty of evidence. No associations between prediabetes and incident depressive symptoms and cognitive impairment were observed (with low or very low certainty of evidence). The association with all-cause mortality was stronger for prediabetes defined by impaired glucose tolerance than for prediabetes defined by HbA1c.

Conclusions/interpretation
Prediabetes was positively associated with risk of all-cause mortality and the incidence of cardiovascular outcomes, CHD, stroke, chronic kidney disease, cancer and dementia. Further high-quality studies, particularly on HbA1c-defined prediabetes and other relevant health outcomes (e. g. neuropathy) are required to support the evidence.

Graphical abstract
Defects-per-unit control chart for assembled products based on defect prediction models
Authors: Verna Elisa , Genta Gianfranco , Galetto Maurizio , Franceschini Fiorenzo 
Published: October 2021

AbstractTypically, monitoring quality characteristics of very personalized products is a difficult task due to the lack of experimental data. This is the typical case of processes where the production volume continues to shrink due to the growing complexity and customization of products, thus requiring low-volume productions. This paper presents a novel approach to statistically monitor defects-per-unit (DPU) of assembled products based on the use of defect prediction models. The innovative aspect of such DPU-chart is that, unlike conventional SPC charts requiring preliminary experimental data to estimate the control limits (phase I), it is constructed using a predictive model based on a priori knowledge of DPU. This defect prediction model is based on the structural complexity of the assembled product. By avoiding phase I, the novel approach may be of interest to researchers and practitioners to speed up the chart’s construction phase, especially in low-volume productions. The description of the method is supported by a real industrial case study in the electromechanical field.
Comparison of continuous and pulsed wave lasers in keyhole welding of stainless-steel to aluminium
Authors: Coroado Julio , Ganguly Supriyo , Williams Stewart , Suder Wojciech , Meco Sonia , Pardal Goncalo 
Published: October 2021

AbstractA continuous wave (CW) and a nanosecond pulsed wave (PW) lasers were used to join 1-mm thick sheets of SS304L (SS) austenitic stainless-steel to AA5251 (Al) aluminium alloy in an overlap joint configuration. The weld shape (penetration depth and width), intermetallic compounds concentration, weld quality (cracking and porosity) and mechanical strength were correlated with the process energy and compared between each laser temporal mode. Successful CW joints were produced with the SS sheet on top of the Al, but the opposite configuration revealed to be impossible for the range of parameters tested. The PW joints were successful with the Al sheet on top of SS, but all the joints cracked at the interface when the opposite configuration was used. The mechanical tests showed that even though it is possible to achieve higher tensile shear load in CW welds due to the larger bonding area, the tensile shear strength revealed to be almost 5 × higher for PW welds at similar applied energy.
MR imaging characteristics of uveal melanoma with histopathological validation
Authors: Ferreira Teresa A. , Jaarsma-Coes Myriam G. , Marinkovic Marina , Verbist Berit , Verdijk Robert M. , Jager Martine J. , Luyten Gregorius P. M. , Beenakker Jan-Willem M. 
Published: October 2021

AbstractPurposeTo evaluate the magnetic resonance imaging (MRI) characteristics of uveal melanoma (UM), to compare them with fundoscopy and ultrasound (US), and to validate them with histopathology.MethodsMR images from 42 UM were compared with US and fundoscopy, and on 14 enucleated cases with histopathology.ResultsA significant relationship between the signal intensity on T1 and pigmentation on histopathology was found (p=0.024). T1 hyperintense UM were always moderately or strongly pigmented on histopathology, while T1-hypointense UM were either pigmented or non-pigmented. Mean apparent diffusion coefficient (ADC) of the UM was 1.16 ± 0.26 × 10−3mm2/s. Two-thirds of the UM had a wash-out and the remaining a plateau perfusion time-intensity curve (TIC). MRI was limited in evaluating the basal diameter of flat tumors. US tends to show larger tumor prominence (0.5mm larger,p=0.008) and largest basal diameter (1.4mm larger,p<0.001). MRI was good in diagnosing ciliary body involvement, extrascleral extension, and optic nerve invasion, but limited on identifying scleral invasion. An increase of tumor prominence was associated with lower ADC values (p=0.030) and favored a wash-out TIC (p=0.028). An increase of tumor ADC correlated with a plateau TIC (p=0.011).ConclusionsThe anatomical and functional MRI characteristics of UM were comprehensively assessed. Knowing the MRI characteristics of UM is important in order to confirm the diagnosis and to differentiate UM from other intra-ocular lesions and because it has implications for treatment planning. MRI is a good technique to evaluate UM, being only limited in case of flat tumors or on identifying scleral invasion.
The radiological interpretation of possible microbleeds after moderate or severe traumatic brain injury: a longitudinal study
Authors: van der Eerden Anke W. , van den Heuvel Thomas L. A. , Maas Marnix C. , Vart Priya , Vos Pieter E. , Platel Bram , Góraj Bozena M. , Manniesing Rashindra 
Published: October 2021

Abstract

Introduction
In order to augment the certainty of the radiological interpretation of “possible microbleeds” after traumatic brain injury (TBI), we assessed their longitudinal evolution on 3-T SWI in patients with moderate/severe TBI.

Methods
Standardized 3-T SWI and T1-weighted imaging were obtained 3 and 26 weeks after TBI in 31 patients. Their microbleeds were computer-aided detected and classified by a neuroradiologist as no, possible, or definite at baseline and follow-up, separately (single-scan evaluation). Thereafter, the classifications were re-evaluated after comparison between the time-points (post-comparison evaluation). We selected the possible microbleeds at baseline at single-scan evaluation and recorded their post-comparison classification at follow-up.

Results
Of the 1038 microbleeds at baseline, 173 were possible microbleeds. Of these, 53.8% corresponded to no microbleed at follow-up. At follow-up, 30.6% were possible and 15.6% were definite. Of the 120 differences between baseline and follow-up, 10% showed evidence of a pathophysiological change over time. Proximity to extra-axial injury and proximity to definite microbleeds were independently predictive of becoming a definite microbleed at follow-up. The reclassification level differed between anatomical locations.

Conclusions
Our findings support disregarding possible microbleeds in the absence of clinical consequences. In selected cases, however, a follow-up SWI-scan could be considered to exclude evolution into a definite microbleed.