bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peculiarities of formation of competitive strategy of the enterprises of flour-milling branch of Ukraine
Authors: Kuznetsova Inna , Gorbatiuk Valentyna , Mulyk Tetiana , Piskun Alyona , Pashchenko Oksana , Hridin Oleksandr 
Published: November 2021

The article deals with the peculiarities of formation of competitive strategy of the enterprises of flour-milling branch of Ukraine. The paper substantiates the necessity to determine the stage of the life cycle of the industry in the process of formation of the competitive strategy. The market analysis of flour-milling industry of Ukraine is carried out on indicators: size of the market, commodity nomenclature, buyers and their behavior, raw material base and intensity of competition. The paper determines that the flour-milling industry of Ukraine is at the stage of growth and has a number of tendencies, such as: decrease

in sales volumes, increase in export volumes, standardization of products and average level of competition intensity. The following stages of the life cycle of the industry are studied: introduction, growth, maturity and decline. The paper proves the necessity of distinguishing the stage of renewal in the life cycle of the industry, which is implemented on the basis of modern technologies. The practical significance of the research consists in developing recommendations for choosing a competitive strategy of the flour mill enterprise in accordance with the stage of the life cycle of the industry. The enterprises of the flour-milling industry of Ukraine, in accordance with the stage of the life cycle of the industry are recommended to form competitive advantages on the basis of the concept of "lean production".
Effects of Flywheel vs. Traditional Resistance Training on Neuromuscular Performance of Elite Ice Hockey Players
Authors: Puustinen Jari , Venojärvi Mika , Haverinen Marko , Lundberg Tommy R. 
Published: November 2021

Abstract
Puustinen, J, Venojärvi, M, Haverinen, M, and Lundberg, TR. Effects of flywheel versus traditional resistance training on neuromuscular performance of elite ice hockey players. J Strength Cond Res 37(1): 136–140, 2023—This study aimed to examine the effects of 8 weeks of flywheel (FW) vs. traditional resistance training on neuromuscular performance of elite ice hockey players during the off-season. Eighteen male players (U-18 to U-21) were assigned to a flywheel group (FG) or traditional training group (TG). The FG (n = 9) performed FW training with 4 different exercises (3–4 sets × 6–7 repetitions). The TG (n = 9) used barbells and free weights (4 sets × 4–12 repetitions). Outcome measures included loaded and unloaded countermovement jumps (CMJs) and a 200 m sprint test that included split times and direction changes. There were no group effects (analysis of covariance with adjustments for pretest values, all p > 0.05, all effect sizes <0.8), suggesting comparable performance improvements between groups. Within-group changes for the unloaded CMJ were 5.7% in FG vs. 4.8% in TG. Similar or slightly greater improvements were seen for the loaded CMJs. For sprint times, there were improvements in both groups for the split time of the first 20 m (FG: −3.2 vs. TG: −2.6%) and also for the 200 m total sprint time (FG −1.8% and TG −1.5%). In conclusion, although FW resistance training improves neuromuscular performance in elite ice hockey players, it does not elicit superior improvements compared with traditional resistance training in players with no prior experience with this training method.
Who Speaks First? Promoting Senior Resident Autonomy on Family-Centered Rounds: A QI Initiative
Authors: Kilinsky Alexandra , Brandt Timothy , Fornari Alice , Goenka Pratichi , Jan Sophia , Kabra Rashi , Khalsa Dev Darshan , Liewehr Sheila , Palumbo Nancy , Subramony Anupama , Leone Nicole 
Published: November 2021

BACKGROUND AND OBJECTIVES
Graduated autonomy is fundamental as trainees transition to independent practice. Family-centered rounds (FCR), the leading model of inpatient rounding in pediatrics, is an opportunity for trainees to demonstrate their competence in leading a health care team, which is an entrustable professional activity for all pediatric residents. At our institution, senior residents (SRs) at baseline performed at a novice level on the basis of the Senior Resident Empowerment Actions 21 (SREA-21), a validated tool that is used to assess SR autonomy during FCR. Our objective for this study was to increase the median percentage of SREA-21 domains in which SRs perform at a competent level from 38% to 75% within 6 months.

METHODS
Researchers observed 4 FCR encounters weekly and calculated SREA-21 scores after 2 weeks on the basis of actions promoting SR autonomy performed by the SR-hospitalist dyad. The primary outcome measure was the percentage of SREA-21 domains in which the SR achieved a competent score on the SREA-21. We used the model for improvement to identify key drivers and test proposed interventions using serial plan-do-study-act cycles. Interventions included creation of unified inpatient SR expectations, introduction of a SR-hospitalist pre-FCR huddle, auditing of FCR interruptions, and direct feedback to the SR-hospitalist dyad after FCR. Run charts were used to track SR and hospitalist scores on the SREA-21.

RESULTS
After multiple plan-do-study-act cycles, there was special cause improvement with a desirable shift upward in the centerline to 100%, which correlated with the project’s interventions and surpassed our goal.

CONCLUSIONS
Using quality improvement methodology, we improved SR autonomy during FCR, as measured by the SREA-21.
Ethnic Disparities in the Care of Opioid-Exposed Newborns in Colorado Birthing Hospitals
Authors: Weikel Blair W. , Palau Mauricio A. , Hwang Sunah S. 
Published: November 2021

OBJECTIVES
Investigate disparities by Hispanic ethnicity in the care of opioid exposed newborns (OENs) in Colorado birthing hospitals within a statewide quality improvement collaborative.

METHODS
This study is a secondary analysis of a quality improvement initiative aimed at standardizing hospital-based care of OENs through implementation of the Eat, Sleep, Console Model. We used statistical process control charts to compare time to special cause variation by Hispanic ethnicity for outcomes including infant length of stay, use of pharmacologic therapy, and breastfeeding eligibility and receipt. Only hospitals that delivered both Hispanic and non-Hispanic OENs during the study period were included, documented maternal ethnicity was required for inclusion. We investigated hospital variation in these outcomes among 4 hospitals that cared for Hispanic OENs for most of the study period.

RESULTS
We analyzed 799 mother–OEN dyads, 241 Hispanic and 558 non-Hispanic. Both Hispanic and non-Hispanic OENs experienced decreases in length of stay overall and among those who received postnatal opioids, although Hispanic OENs achieved these decreases 3 annual quarters after non-Hispanic OENs. Pharmacologic therapy use decreased by 55% for Hispanic OENs and 60% for non-Hispanic OENs. Hispanic OENs experienced a 1-quarter delay for this decrease.

CONCLUSIONS
Although this quality improvement initiative resulted in positive outcomes for Hispanic and non-Hispanic OENs, improvement was delayed among Hispanic infants, indicating a need to explore and address care practices of Hispanic mothers and infants affected by opioid use disorders.
Use of a Sterile Collection Process to Reduce Contaminated Peripheral Blood Cultures
Authors: Bram Sarah , Schmidt Teresa M. , Lloyd Justin P. , Ellsworth Samantha , Quayle Kimberly , Srinivasan Mythili 
Published: November 2021

BACKGROUND
Contaminated blood cultures pose a significant burden by subjecting children to unnecessary testing, procedures, and antibiotics and increasing health care costs. The aim of our quality improvement (QI) initiative was to decrease the percentage of contaminated peripheral blood cultures in our pediatric emergency department (ED) from an average of 6.7% to &lt;3% over a 16-month period.

METHODS
The QI initiative was implemented in the pediatric ED of a tertiary care children’s hospital. Interventions included change of the peripheral blood culture collection from a clean to a sterile process, nursing education, and individualized feedback. The primary outcome measure was the percentage of contaminated peripheral blood cultures. The process measure was the percentage of nurses who completed 75% to 100% of the steps of the sterile collection process, as measured by self-reporting in audit cards. The balancing measures were time from antibiotic ordering to time of administration and ED length of stay.

RESULTS
We decreased the percentage of contaminated peripheral blood cultures threefold from a baseline (June 2, 2018, to December 31, 2018) of 6.7% to 2.1% during the intervention period (January 1, 2019, to April 30, 2020). Ninety-eight percent of nurses who completed audit cards reported performing 75% to 100% of the steps of the new sterile process. There was no significant difference in the average time from antibiotic ordering to antibiotic administration or ED length of stay between the baseline and intervention periods.

CONCLUSIONS
Use of a sterile blood culture collection process, in addition to nursing education and individualized feedback, is an effective method to decrease peripheral blood culture contamination rates in a pediatric ED.
Creation and Implementation of a Hospitalist-Run Propofol Sedation Program
Authors: McAndrew Lisa , Patel Melissa , Werner Amy , Aredas Brenna , Winser Kyle , Dubow Scott 
Published: November 2021

BACKGROUND
Pediatric hospitalists increasingly provide sedation outside the operating room. Given the large body of safety data available, propofol was identified as a beneficial addition to our hospitalist-run sedation service’s medication repertoire. Currently, the training required for hospitalists to provide sedation is defined and determined locally by individual institutions.

METHODS
We convened a task force to develop and implement training for hospitalists in the use of propofol for deep sedation. After implementing training, we analyzed the outcome of patients receiving propofol for deep sedation for MRI, including the adverse event rate and successful completion rate. An adverse event was defined as a significant desaturation, persistent upper airway obstruction, laryngospasm, administration of neuromuscular blockade, conversion to anesthesia, call for additional backup, or if the procedure was not able to be completed. Successful completion was defined as any patient being able to complete the imaging study or procedure with sedation performed by a hospitalist physician.

RESULTS
Between September 2015 and September 2018, sedation services sedated 12 979 patients, 3929 of whom were deeply sedated with propofol. During this period, the trained hospitalists had an adverse event rate of 3.6% and a 98.9% rate of successful completion of all studies or procedures when using propofol for deep sedation.

CONCLUSION
With a comprehensive training program for hospitalists in the administration of propofol, we provided effective sedation for a selective population of patients. We now have a standard approach that uses credentialed hospitalists to train new faculty for propofol administration.
Improving Discharge Instructions for Hospitalized Children With Limited English Proficiency
Authors: Choe Angela Y. , Schondelmeyer Amanda C. , Thomson Joanna , Schwieter Andy , McCann Erin , Kelley Jodi , Demeritt Brenda , Unaka Ndidi I. 
Published: November 2021

BACKGROUND AND OBJECTIVES
Patients with limited English proficiency (LEP) have increased risk of adverse events after hospitalization. At our institution, LEP families did not routinely receive translated discharge instructions in their preferred language. Our objective for this study was to increase the percentage of patients with LEP on the hospital medicine (HM) service receiving translated discharge instructions from 12% to 80%.

METHODS
Following the Model for Improvement, we convened an interdisciplinary team that included HM providers, pediatric residents, language access services staff, and nurses to design and test interventions aimed at key drivers through multiple plan-do-study-act cycles. Interventions addressed the translation request process, care team education, standardizing discharge instructions for common conditions, and identification and mitigation of failures. We used established rules for analyzing statistical process control charts to evaluate the percentage of patients with translated discharge instructions for all languages and for Spanish.

RESULTS
During the study period, 540 patients with LEP were discharged from the HM service. Spanish was the preferred language for 66% of patients with LEP. The percentage of patients with LEP who received translated discharge instructions increased from 12% to 50% in 3 months and to 77% in 18 months. For patients whose preferred language was Spanish, the percentage increased from 16% to 69% in 4 months and to 96% in 18 months.

CONCLUSIONS
Interventions targeting knowledge of the translation process and standardized Spanish discharge instructions were associated with an increased percentage of families receiving translated discharge instructions. Future work will be used to assess the impact of these interventions on postdischarge disparities, including emergency department revisits and readmissions.
Synthesis and behavior of bulk iron nitride soft magnets via high-pressure spark plasma sintering
Authors: Monson Todd C. , Zheng Baolong , Delaney Robert E. , Pearce Charles J. , Zhou Yizhang , Atcitty Stanley , Lavernia Enrique 
Published: November 2021

Abstract
In this study, dense bulk iron nitrides (FexN) were synthesized for the first time ever using spark plasma sintering (SPS) of FexN powders. The Fe4N phase of iron nitride in particular has significant potential to serve as a new soft magnetic material in both transformer and inductor cores and electrical machines. The density of SPSed FexN increased with SPS temperature and pressure. The microstructure of the consolidated bulk FexN was characterized with X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and superconducting quantum interference device (SQUID) magnetometry. XRD revealed a primary phase of Fe4N with secondary phases of Fe3N and metallic iron. Finite element analysis (FEA) was also applied to investigate and explain localized heating and temperature distribution during SPS. The effects of processing on interface bonding formation and phase evolution were investigated and discussed in detail to provide insight into fundamental phenomena and microstructural evolution in SPSed FexN.

Graphic abstract
TARİHSEL SÜREÇTE AKÇAABAT’TA BAĞCILIK
Authors: TOPAL Zehra 
Published: November 2021

Kaybedildiğinde önemi anlaşılan, çoğu zaman geri kazanılamayan değerlerimiz zamana ve şartlara göre bir bir yok olup gitmekte, her geçen gün bunlara bir yenisi eklenmektedir.
Doğu Karadeniz Bölgesi’nde bir zamanlar başlıca tarımsal üretim kalemlerinden birini teşkil eden, ancak günümüzde ortadan kalkan üzüm yetiştiriciliği yani bağcılık da bunlardan biridir.
Bu çalışmada, bağ alanı ve üzüm üretimi bakımından günümüzde tarım bölgelerimiz arasında adı geçmeyen, Trabzon’a bağlı Akçaabat ilçesinin bağcılık geçmişi ele alınmıştır. Çalışmanın ana kaynakları fethin ilk yüzyılında kayda alınan Tahrir defterleri başta olmak üzere Osmanlı Arşivi kayıtlarıdır. Bunların yanında bahsi geçen kaynaklarda belirtilen verilerin günümüz ile olan bağlantılarının kurulması amacıyla sözlü kültür kaynaklarına da başvurulmuştur. Akçaabat’ta bağcılık yapılan köyler, köylerdeki asma adeti, üretilen şıra ve şarap miktarları ile zamanla bağcılıkta meydana gelen gerilemenin nedenleri, ortadan kalkması gibi konular irdelenmeye çalışılmıştır.
Resumos I Congresso Internacional de Intervenção na Saúde e no Exercício: pensando na Pós-pandemia - I CIISE
Authors: De Freitas Brito Aline 
Published: November 2021

O I Congresso Internacional de Intervenção na Saúde e no Exercício: pensando na Pós-pandemia - CIISE foi um evento de caráter científico que teve como objetivo promover a discussão do conhecimento sobre as demandas de Intervenção na Saúde e no Exercício na situação de pós-pandemia no Brasil e no Mundo. O evento nasce como produto do Projeto de Extensão "Faciologia – Descomplicando a Fisiologia Humana" e do canal do YouTube "COM CIÊNCIA – todo conhecimento é rico em ciência" [vinculado à Universidade de Pernambuco (UPE)] e foi coordenado pela Profa. Dra. Aline de Freitas Brito. O CIISE foi realizado nos dias 03/06/2021 (14h às 17h), 04 e 05/06/2021 (08h às 19h), com transmissão online pelo YouTube, através do Canal "COM CIÊNCIA" https://www.youtube.com/channel/UCpo2da5QwwxoTzH0fADoD8Q e contou com a participação de 17 palestrantes renomadas na área da Saúde e do Exercício, todas pesquisadoras e docentes de diversas universidades do Brasil e do Mundo.
Myeloid Metabolism as a New Target for Rejuvenation?-Comments on Restoring Metabolism of Myeloid Cells Reverses Cognitive Decline in Ageing. Nature. 2021 Feb;590(7844)122-128
Authors: Knobloch Marlen , Paolicelli Rosa C. 
Published: November 2021

Abstract
Research led by Katrin Andreasson suggests that fixing age-induced metabolic defects in myeloid cells would suffice to reverse cognitive impairment and to restore synaptic plasticity to the level of young subjects, at least in mice. This opens up the possibility to develop rejuvenating strategies by targeting immune dysfunction.
Towards automatic detection and classification of orca (Orcinus orca) calls using cross-correlation methods
Authors: Palmero Stefano , Guidi Carlo , Kulikovskiy Vladimir , Sanguineti Matteo , Manghi Michele , Sommer Matteo , Pesce Gaia 
Published: November 2021

Abstract
Orca (Orcinus orca) is known for complex vocalisation. Their social structure consists of pods and clans sharing unique dialects due to geographic isolation. Sound type repertoires are fundamental for monitoring orca populations and are typically created visually and aurally. An orca pod occurring in the Ligurian Sea (Pelagos Sanctuary) in December 2019 provided a unique occasion for long-term recordings. The numerous data collected with the bottom recorder were analysed with a traditional human-driven inspection to create a repertoire of this pod and to compare it to catalogues from different orca populations (Icelandic and Antarctic) investigating its origins. Automatic signal detection and cross-correlation methods (R package warbleR) were used for the first time in orca studies. We found the Pearson cross-correlation method to be efficient for most pairwise calculations (> 85%) but with false positives. One sound type from our repertoire presented a high positive match (range 0.62–0.67) with one from the Icelandic catalogue, which was confirmed visually and aurally. Our first attempt to automatically classify orca sound types presented limitations due to background noise and sound complexity of orca communication. We show cross-correlation methods can be a powerful tool for sound type classification in combination with conventional methods.
Spatial and Temporal Evolution of Ecological Vulnerability Based on Vulnerability Scoring Diagram Model in Shennongjia, China
Authors: Cao Jia-shuo , Yang Yu-qi , Deng Zheng-yu , Hu Yuan-dong 
Published: November 2021

Abstract
Background
Shennongjia is one of the most important ecological function areas and ecologically vulnerable zones in the world. With the rapid development of social economies, especially tourism, the ecological environment of Shennongjia has experienced profound changes. To describe an assessment method of ecological vulnerability, explain its application in Shennongjia, and propose optimization strategies to reduce the risk of ecosystem vulnerability and maintain regional ecological security and stability.
Results
(1) During the study period, the overall ecological vulnerability of Shennongjia is in a mild vulnerability level, exhibiting differentiation characteristics of high in the northeast and low in the southwest. High vulnerability zones are mainly distributed in the main towns and roads of Shennongjia. (2) The risk of ecological vulnerability of the entire region presents the characteristics of continuous decline. The ecological vulnerability composite index reaches the lowest value of 2.51 in 2018. (3) Land-use types, population density, and vegetation coverage are the main factors driving the evolution of ecological vulnerability. (4) A high level of coupling coordination exists between ecological vulnerability and landscape patterns, and the contribution of patch number and aggregation index to ecological vulnerability is substantial.
Conclusions
Analyses of the ecological vulnerability of Shennongjia shows that the entire region is in a mild vulnerability level. The extreme vulnerability risk of the northeast, south and southwest areas appears gradually, the vulnerability degree of the ecological environment shows polarization. The evolution of ecological environment in Shennongjia is the result of the interaction between human activities and natural environment. This study offers an effective way to assess ecological vulnerability and provides some strategies and guidance for improving ecological security.
Identification of a FLG-wide-type bladder cancer subtype with poor prognosis and prediction use in immune checkpoint
Authors: Chen Liang , Xiong Liulin , Chen Weinan , An Lizhe , Wang Huanrui , Hong Yang , Wang Huina , Huang Xiaobo 
Published: November 2021

Abstract
Background

Bladder cancer (BLCA) is one of most common urinary tract malignant tumor and immunotherapy have generated a great deal of interest in BLCA. Immune checkpoint blockade (ICB) therapy has significantly progressed the treatment of BLCA. Multiple studies have suggested that specific genetic mutations may serve as immune biomarkers for ICB therapy.
Objective

In this study, we aimed to investigate the role of mutations genes and subtypes in prognosis and immune checkpoint prediction in BLCA.
Method

Mutation information and expression profiles were acquired from The Cancer Genome Atlas (TCGA) database. Integrated bioinformatics analysis was carried out to explore the mutation genes of BLCA. Functional enrichment analysis Gene Ontology (GO) and Gene set enrichment analysis (GSEA) was conducted. The infiltrating immune cells and the prediction of ICB between different subtypes group were explored using immuCellAI algorithm.
Results

The mutation genes Filaggrin (FLG) gene were identified. Following the study on its subtypes and functional enrichment analysis, Sub2 of FLG-wide type was found to have relationships with poor prognosis and immune infiltration BLCA. What’s more, Sub2 of FLG-wide type may be used as a biomarker to predict the prognosis of BLCA patients receiving ICB.
Conclusion

This research provides a new basis and ideas for guiding the clinical application of BLCA immunotherapy.