bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determination of the binding mechanism of cobalt(II) meso-tetraphenyl porphyrin with plant-esterase
Authors: Liu Zishan , Dong Liang , Li Feifeng , Hou Changjun , He Kun , Huo Danqun 
Published: May 2021

Abstract
Plant-esterase (EC 3.1.1.X) has received much attention because plant esterase and acetylcholinesterase (AChE) share a similar sensitivity towards organophosphorus (OP) pesticides detection with the same inhibition mechanism. To improve the analytical performance, tetraphenyl metal porphyrin, as an indicator was introduced to combine with plant-esterase. The time of reach equilibrium in PBS solution was shortened after adding plant-esterase by assaying the intensify change of the porphyrin spectrum. Meanwhile, intensify of porphyrin spectrum with plant-esterase was increased compared with that of only the porphyrin spectrum in solution. Tetraphenyl metal porphyrin, such as cobalt(II) meso-tetraphenyl porphyrin, is a mixed reversible inhibitor of plant-esterase from kinetic parameters. The combination ratio of plant-esterase and porphyrin is 2:1. On the other hand, the interaction between CoTPPCl and plant-esterase is the strongest among all tested tetraphenyl metal porphyrin. And the mixed system (CoTPPCl-plant-esterase) showed the best sensitivity towards the tested pesticide. All these results indicated that a complex system composed of tetraphenyl metal porphyrin and plant-esterase was fit for detecting pesticides. They make meaningful guidance on the further design of sensing material in monitoring pesticides.
Geology of Ali Khanzai Block of Zhob Ophiolite, Balochistan, Pakistan
Authors: Rehman Saeed Ur , Kakar M. Ishaq , Khan Muhammad Ayoub , Naeem Abdul 
Published: May 2021

Abstract
The Zhob Ophiolite is divided into Naweoba, Omzha and Ali Khanzai blocks. Ali Khanzai Block is further divided into ultramafic, mafic, and lava units which are surrounded by sedimentary rocks successions. The ultramafic unit contains ultramafic tectonic and ultramafic cumulate, mafic rock unit consists of foliated and layered gabbros and mafic dykes are doleritic in composition. Volcanic–volcaniclastic–pelagic rocks unit consists of thick volcanic pillow basalt, hyaloclastite, bedded chert, pelagic limestone and hemipelagic mudstone. The metamorphic sole rocks are tectonically high distorted and dismembered, comprising of amphibolite and greenschist facies. They might have formed through the process of early intra-oceanic obduction of the ophiolite. All units make thrusted contacts and are highly deformed. Petrography and geochemical studies divide the Ali Khanzai Block into rock types such as gabbro, olivine gabbro, dolerite, basalt, basaltic andesite and basaltic trachy-andesite, chert, mudstone, and limestone, dunite, serpentinite, harzburgite, and wehrlite. Mafic dyke intrusions crosscut mantle rocks of block. The mantle rocks are altered, deformed, and deeply weathered, maybe residual melting of enriched mantle peridotite. The contact relationship of dolerite dykes with peridotite indicta that they are late magmatic intrusions. The Crustal gabbros are partially chloritic and sericitic and occur within mantle peridotite,, they may have formed from fractional crystallization in a magma chamber. The volcanic-volcaniclastic-pelagic sediments surround mantle and crustal rock units. It might be a mélange in nature is much like that of the Bagh Complex found beneath the Muslim Bagh Ophiolite, and other ophiolites around the world.
Do we really have an Immigration Crisis?
Authors: Hana Tommy 
Published: May 2021

The 21st century can be characterized as the century of movement and rapid globalization. This megatrend continues to thrive as political, social, and economic strife progresses across the globe. Not only have we seen mass exoduses from countries plagued with ethno-racial and religious warfare, but rapid urbanization is pulling people out of rural areas and into cities. It is undeniable that the translocation of large ethnic groups into Western countries has instigated tension between Westerners and migrants due to evolutionary predispositions and prejudices towards migrants and refugees, as well as a nation’s resource limitations. This poster seeks to examine the history and current trends of migration, using an intersectional analysis on the grounds of Darwinian evolutionary theory.
Exploring the Impact of Adjacent Land Use on the Wilderness Character of National Parks in Northern Canada
Authors: Jacklin Courtenay 
Published: May 2021

This study investigates the potential for competing land use along the boundaries of national parks in northern Canada to impact the wilderness character of these parks. Information synthesized from park documents was used to summarize the wilderness character of northern national parks and the potential for adjacent development. Using Kluane National Park and Reserve in the southwest Yukon as a case study, a GIS-based approach was used to analyze mineral development and wildlife habitat in the Kluane region, and results of a survey distributed to park visitors provided the foundation for analyzing the importance of the wilderness within the park. Results illustrate that park visitors associate wilderness with ecosystem protection and the preservation of wildlife habitat, and consider the opportunity to encounter untouched nature as the most important value associated with Kluane National Park and Reserve. The majority of critical habitat for wildlife found in the Kluane region, including several species listed as threatened or special concern, is found in the area immediately adjacent to the park. This area also has a high concentration of quartz and placer claims, including a proposed large-scale, open-pit PGM-Ni mining operation. There is potential for increased mineral development in the area to impact the wilderness character of the park as landscape disturbance increases, compromising wildlife habitat. Other national parks in northern Canada may also face similar challenges. As development in northern Canada increases, the management of land adjacent to national parks will become increasingly important to the preservation of wilderness character within these parks.
Performance and Propriety: Representations of Madame Vestris as Actress and Theatre Manager in 19th-century Print Media
Authors: Lau Lorraine 
Published: May 2021

In 19th-century Britain, women professionally involved in theatre faced a double bind: their popularity depended on the commodification of their bodies, yet their sexual availability excluded them from the propriety of domestic middle-class femininity that Victorian culture valued highly. This project aims to offer insight into how these women negotiated their respectability by examining the career of Lucia Elizabeth Vestris, an actress and theatre manager, through an analysis of contemporary print media. The poster compares Madame Vestris’ reputation at the beginning and end of her career in 1820 and 1855 respectively. In particular, I have focused on Vestris’ transition from salacious starlet, associated with light comedy and the sexualized breeches’ role, to esteemed manager, known for constructing the Lyceum Theatre as a visual spectacle suited for refined audiences. Drawing from a variety of 19th-century London periodicals such as the Times and the Inquirer, I examine Vestris as understood by a body of mainly middle-class male critics, exploring implications behind their simultaneous attraction to and moral repulsion of young Vestris’ sexualized self-presentation, as well as their positive response to her upmarket renovation of the Lyceum as a sign of her respectability. Ultimately, the poster reflects how notions of gender and class heavily shaped the Victorian discourse on theatre: while the actress as a profession was deemed inherently sexualized, women working in the theatre could achieve some degree of social mobility if they packaged their sex appeal as socially acceptable commodities for bourgeois audiences.
The Use of Matrix Training to Teach Concurrent Appropriate Actions and Vocalizations during Sociodramatic Play in a Child with Autism
Authors: Sedgwick Hayley 
Published: May 2021

Play skills are important for children to develop because they expand social and communicative skills (Lewis, 2003). Children with autism show impaired play skills because of repetitive or stereotypic behaviour (Jung & Sainato, 2013). Matrix training is defined as a generative form of instruction in which targets are organizaed in a matrix, and it is commonly used to teach communication (Axe & Sainato, 2010). After some skill combinations are taught, other untaught skill combinations within the matrix are tested for generative learning and responding (MacManus et al., 2015). A multiple-probe design was employed to test whether matrix training can teach play actions and language use during sociodramatic play in a 6-year-old boy with autism in an intensive behavioural intervention setting. Scripted actions and vocalizations were each arranged in a two-dimensional matrix and probe data were collected for correct responding with both components of the target play skills. The data showed an increasing trend and after teaching of three target combinations, the participant generalized four of the six alternative untrained combinations for actions and vocalizations. The mean level of acquired combinations was 83.33% by the end of the generalization phase. A visual analysis, using PEM, showed that the use of two parallel matrices was effective to concurrently increase both action and vocalization components of play.
Building an Elliptic Curve Cryptography to Encode and Decode Vietnamese Texts
Authors: Trung Mai Manh , Tuan Do Trung , Do Le Phe 
Published: May 2021

This article presents building an Elliptic curve cryptography and using it to encode and decode Vietnamese text. Here we have illustrated the prime number p = 151 in the future, which will use a large prime number. We consider an elliptic curve with a total score of 172 points. Encode and decode with standard Vietnamese text and combine with the special characters in ASCII code. The program is designed and installed and on the C# environment to give the correct result of the encryption algorithm.
KeywordsData sequence, Decryption, Discrete logarithm, Elliptic curve, Elliptic curve cryptosystem, Encryption, Public key
References[1] Koblitz, “Elliptic curve cryptosystems”, Mathematics of Computation”, 203 - 209, 1987.[2] Miller, “Uses of elliptic curves in cryptography, Advances in Cryptology - Crypto”, Lecture Notes in Computer Science, SpringerVerlag, 1986, pp. 417-426.[3] Sugantha Priya, Dr.M. Mohanraj, “A Review on Secure Elliptic Curve Cryptography (ECC) and Dynamic Secure Routing Link Path Detection Algorithm (DSRLP) Under Jamming Attack”, ISSN 68(30) (2020) 0474-9030.[4] Negin Dinarvand, Hamid Barati, “An efficient and secure RFID authentication protocol using ellipticcurvecryptography”,SpringerfScience+Business Media, LLC, 2017[5] Utku Gulen, Selcuk Baktir, “Elliptic Curve Cryptography for Wireless Sensor Networks Using the Number Theoretic Transform”, journal-sensors, Published: 9 March, 2020.[6] Sravana Kumar, C.H. Suneetha, A.R. Chandrasekh, “Encryption of Data Using Elliptic Curve Over Finite Fields”, International Journal of Distributed and Parallel Systems (IJDPS). 3(1) (2012) 301-308.[7] Amounas, E.H. El Kinani, ECC Encryption and Decryption with a Data Sequence, Applied Mathematical Sciences 6(101) (2012) 5039-5047.[8] Vu Thi Hai Ha, Dinh Thi Hang, Bui Dang Binh, “The influence of volume on the formant of vowels and the identification of Vietnamese speakers”, Vietnam Institute of Linguistics, 2015.[9] Enge, “Elliptic curves and their applications to cryptography”, Norwell, MA: Kulwer Academic publishers, 1999.[10] Neil Koblitz, “An Elliptic Curve implementation of the finite field digital signature algorithm”, in Advances in cryptology,(CRYPTO 1998), SpringerLecture Notes in computer science, 1462 (1998) 327-337.[11] S. Sandeep, Kumar, “Elliptic curve cryptography for constrained devices”, PhD thesis, Ruhr-University Bochum, June, 2006.
Estrés académico y sintomatología de gastritis en los beneficiarios del comedor Universitario, Chachapoyas, 2017
Authors: Tirado Cusma Jeiner Jimy , Tejada Muñoz Sonia 
Published: May 2021

El presente estudio fue de enfoque cuantitativo, relacional, observacional, prospectivo, transversal y analítico cuyo objetivo fue determinar la relación que existe entre el estrés académico y la sintomatología de gastritis en beneﬁciarios del comedor de la Universidad Nacional Toribio Rodriguez de Mendoza de Amazonas, Chachapoyas – 2017. Se tuvo una muestra de 45 beneﬁciarios categorizados. Para la recolección de datos se utilizó el método de la encuesta, técnica del cuestionario, los instrumentos utilizados fueron: inventario SISCO de estrés académico con conﬁabilidad de 0.90 y el test de sintomatología de gastritis validado mediante la prueba binomial cuyo valor fue 8.88 (adecuado) y la determinación de conﬁabilidad por Alfa de Crombach obteniéndose un valor de 0.85 (alta conﬁabilidad). Los resultados fueron: el 71.1% presentaron sintomatología de gastritis con estrés académico moderado, el 20% no presentó sintomatología de la gastritis y tiene estrés académico leve y el 8.9% no tiene sintomatología de gastritis y tienen estrés académico moderado. La hipótesis fue contrastada con la prueba 2estadística no paramétrica de la Ji-cuadrada X^2 = 27.692; Gl = 2; p = 0.023 &lt; α = 0.05, aceptando la Hipótesis alterna (H). Concluyéndose que el estrés académico tiene relación signiﬁcativa con la sintomatología de la a gastritis
Neurological Examination in a Rare Case of Upper Motor Neuron Injury: A Case Report
Authors: Miller James Austin , Sheldon Nicholas Luke 
Published: May 2021

Background Neurological complaints are common in the field of sports medicine and range from simple nerve root compression to complex postconcussive syndrome. As a result, a concise clinical examination of the neurological system must be performed. Case Presentation A 23-year-old man presented to the clinic with a 2-week history of right-sided ankle weakness and difficulty walking. Physical examination revealed reduced strength in dorsiflexion and great-toe extension and difficulty performing a full calf raise; however, sensation was intact, reflexes were equal, and Babinski and clonus tests were negative. His symptoms progressed rapidly over a period of 2 weeks, resulting in a complete foot drop. Outcome and Follow-Up Subsequent imaging of the lumbar spine and brain revealed a mass in the motor cortex abutting the falx cerebri, later shown to be a stage 3 anaplastic astrocytoma. Discussion This case highlights the limitation of pathological reflex testing for excluding upper motor neuron lesions and presents an appropriate clinical-reasoning process in the neurological examination of an unusual case. JOSPT Cases 2021;1(1):15–18. doi:10.2519/josptcases.2021.10034
Clinical Utility of Lumbar Anteroposterior Mobilizations in a Patient With Degenerative Lumbar Spondylolisthesis: A Case Report
Authors: Jones Brian , Bux Christopher 
Published: May 2021

Background and Purpose Lumbar anteroposterior mobilizations (LAPMs) are seldom referenced in the literature but may be useful in the treatment of degenerative lumbar spondylolisthesis (DLS). This case details successful management of a 53-year-old man with DLS and lower extremity pain through LAPM and exercise. Case Description Lumbar anteroposterior mobilization was implemented into the plan of care after unsatisfactory improvement with lumbar posteroanterior mobilization and exercise. Lumbar anteroposterior mobilization helped to facilitate improvement in lumbar active range of motion and pain, allowing expedited exercise progression and achievement of patient goals. Outcomes At discharge, the patient demonstrated full, pain-free lumbar active range of motion in all planes except extension and reported a 58% improvement in Oswestry Disability Index score over that of his initial evaluation. He achieved his goals of avoiding surgery and beginning an exercise program to manage his health. Conclusion This case suggests that LAPM should be considered as part of a comprehensive DLS treatment strategy. JOSPT Cases 2021;1(1):42–48. doi:10.2519/josptcases.2021.9798
A Symptom-Based Approach to Sports-Related Concussion Rehabilitation in Adolescents: A Case Series
Authors: Walston Lindsay , Walston Zachary , McLester Cherilyn , Yake Dale 
Published: May 2021

Background Current research supports active rehabilitation for individuals recovering from concussion, but does not offer objective thresholds to guide treatment progression. The purpose of this study was to demonstrate the feasibility of utilizing standardized symptom provocation thresholds to guide exercise progression in concussion rehabilitation. Case Presentation Seven patients from 14 to 17 years of age presented to outpatient physical therapy for treatment of sports-related concussion. Each patient completed a 3-phase symptom-based treatment plan. A self-reported increase in symptoms between 2 and 4 points on a visual analog scale (range, 0–10) was used to determine exercise intensity. Outcome and Follow-Up All patients demonstrated full resolution of self-reported symptoms and objective measures of impairment before returning to full sport participation. Discussion The outcomes of this case series suggest that the use of standardized symptom scores may be feasible in treating individuals with sports-related concussion. JOSPT Cases 2021;1(1):5–12. doi:10.2519/josptcases.2021.9874
Stability Indicating Assay Method (Siam) For Determination Of Semaglutide By Hplc Using Qbd Approach
Authors: Merugu Manasa  , Vijey Aanandhi M  
Published: May 2021

An accurate, precise, robust and stability-indicating RP-HPLC method was developed for the estimation of Semaglutide using QbD approach. After conducting several trials using CCD method, one desirable method was optimized. Stationary phase selected was Kromasil C18 (250×4.6 mm, 5 µm) and potassium dihydrogen orthophosphate (pH 2) and Methanol used as mobile phase in the ratio of 61.2: 38.8. Detection was carried out at the wavelength 230nm. Flow rate selected for separation was 0.98ml/min and the temperature of 29.150C. The retention time was found to be 2.518 at the run time of 5min. The developed method was subjected to validation as per ICH guidelines. Semaglutide linear in the concentration range of 0-9µg/ml and the regression coefficient was found to be 0.999. The developed method was accurate, precise and robust. When a sample solution subjected to stress conditions like acid hydrolysis, neutral hydrolysis, photodegradation and thermal degradation, no degradation products were observed. In basic degradation studies two degradation products and oxidative conditions one degradation product was observed. From stress studies, we can observe that the degradation of Semaglutide was less than 10 in all conditions, and there is no impact of degradation products on system suitability parameters. The peak was homogenous I all conditions, thus proving the stability-indicating nature of the method. This method can be applied for the determination of Semaglutide in the drug substance.
Antioxidant studies of 3-(5-(2,4-dichlorophenoxy)-3-methyl-1-phenyl-1Hpyrazole-4-yl)-1-(furan-2-yl)prop-2-en-1-one
Authors: Ganesh Somashekarachar  , Arpita Goswami  , Kannika Byadarahalli Ravindranath  , Madan Kumar Shankar  , Manju Nagaraja  
Published: May 2021

Chalcones are flavonoid precursors, abundant in edible plants. The pyrazole moieties in chalcones show various pharmacological activities. Notably, Chalcone-based structures exhibit numerous pharmacological activities like antiinflammatory, antibacterial, antitumor, antioxidant functions because of having α, β-unsaturated ketone moiety. Such broad spectrum biological activities were also observed in several nitrogen containing heterocycles. Among the heterocyclic systems, pyrazole stand unique. All these observations led us to design and synthesize pyrazole fused hybrid thiophenechalcone molecule 3-(5-(2,4-dichlorophenoxy)-3-methyl-1-phenyl-1H-pyrazole-4-yl)-1-(furan-2-yl)prop-2-en-1-one (3a). The synthesis was performed using base catalyzed reaction of pyrazole aldehyde and acetyl furan. Further characterization of the molecule was done by spectroscopy and antioxidant studies. Spectroscopic methods included Fourier transform infrared (FTIR), nuclear magnetic resonance (NMR) and mass spectra (MS). The antioxidant potency of the compound was carried out based on the scavenging activity of 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH). This compound showed moderate free radical scavenging activity of 45.12 %.
MarkIt: A Collaborative Artificial Intelligence Annotation Platform Leveraging Blockchain For Medical Imaging Research
Authors: Witowski Jan , Choi Jongmum , Jeon Soomin , Kim Doyun , Chung Joowon , Conklin John , Figueiro Longo Maria Gabriela , Succi Marc D. , Do Synho 
Published: May 2021

Current research on medical image processing relies heavily on the amount and quality of input data. Specifically, supervised machine learning methods require well-annotated datasets. A lack of annotation tools limits the potential to achieve high-volume processing and scaled systems with a proper reward mechanism. We developed MarkIt, a web-based tool, for collaborative annotation of medical imaging data with artificial intelligence and blockchain technologies. Our platform handles both Digital Imaging and Communications in Medicine (DICOM) and non-DICOM images, and allows users to annotate them for classification and object detection tasks in an efficient manner. MarkIt can accelerate the annotation process and keep track of user activities to calculate a fair reward. A proof-of-concept experiment was conducted with three fellowship-trained radiologists, each of whom annotated 1,000 chest X-ray studies for multi-label classification. We calculated the inter-rater agreement and estimated the value of the dataset to distribute the reward for annotators using a crypto currency. We hypothesize that MarkIt allows the typically arduous annotation task to become more efficient. In addition, MarkIt can serve as a platform to evaluate the value of data and trade the annotation results in a more scalable manner in the future. The platform is publicly available for testing on https://markit.mgh.harvard.edu.
Kajian Rancangan Instalasi Penerangan Pada Laboratorium Eksplorasi Dan Mekanika Batuan Politeknik Muara Teweh
Authors: Teruna Juli Chandra 
Published: May 2021

Politeknik Muara Teweh memiliki fasilitas gedung pendidikan yang memadai, begitu juga laboratorium sebagai wadah eksperimen dan penelitian untuk mengembangkan ilmu pengetahuan khususnya teknik pertambangan telah tersedia. Salah satu laboratorium yang ada di Politeknik Muara Teweh adalah Laboratorium Eksplorasi dan Mekanika Batuan Program Studi Teknik Pertambangan, dimana di laboratorium ini terdapat beberapa peralatan baru sehingga perlu direncanakan instalasi penerangan yang baik agar pelaksanaan kegiatan praktikum dapat berjalan dengan baik. Berdasarkan hasil observasi yang dilakukan, Laborarorium Eksplorasi dan Mekanikan Batuan memiliki luas ruangan 60 m2 dan tinggi ruangan 3,2 m dengan indeks ruangan 1,6. Faktor refleksi dinding sebesar 0,5 dan langit-langit sebesar 0,7. Kebutuhan minimum pencahayaan untuk peralatan sesuai dengan persyaratan kerja adalah 200 lux sehingga berdasarkan hasil penelitian, diperlukan 6 armatur lampu yang masing-masing dapat menghasilkan fluks cahaya sebesar 5200 lumen dengan intensitas cahaya mencapai 413,8 candela sehingga total kuat penerangan di tengah ruangan mencapai 211 lux. Kata Kunci : Intensitas cahaya, fluks cahaya, iluminasi, faktor refleksi, indeks ruangan.