bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evolución de la terapia sustitutiva renal
Authors: Coronado Daza Jorge Antonio 
Published: January 2021

La enfermedad renal crónica (ERC) es un problema de salud pública mundial. La cuenta de alto costo de Colombia a 2013 reportó la existencia de 22.926 pacientes en terapia de diálisis, 5.941 con trasplante renal y 1.015.124 pacientes con ERC en estadios I - IV, potenciales a progresary requerir terapia sustitutiva renal (TSR), para una incidencia aproximada de ingreso a diálisis de 65 personas por millón de habitantes (1). En Estados Unidos en el 2011 se encontraban en diálisis 430.723 pacientes y 185.626 estaban trasplantados (2).En 1945 Willen Kolff realizó la primera sesión de hemodiálisis con éxito.La cual ha ido evolucionando desde el uso en pacientes agudos hasta laaplicación en crónicos. En 1972 se aprobó en EEUU la hemodiálisis crónicapara el tratamiento de todos los pacientes con ERC avanzada (3).
Vigilancia fetal durante el trabajo de parto
Authors: Salcedo Ramos Francisco , Méndez Rodríguez Rogelio , Vallejo Navarro Carolina 
Published: January 2021

La monitoria fetal intraparto hace parte de las pruebas para la valoración del bienestar fetal. Es método de fácil realización e interpretación, no invasivo, de bajo costo, reproducible, sin efectos secundarios ni contraindicaciones. El objetivo fundamental del estudio es la evaluación del estado fetal durante el parto, identificando los fetos que posiblemente puedan estar comprometidos. Ello se determina por alteraciones en lassiguientes variables. [A] Frecuencia, variabilidad y desaceleraciones del ritmo cardíaco fetal. [B] Movimientos fetales. [C] Cambios en la actividad cardíaca en relación con la actividad uterina. Los hallazgos permiten clasificar el estado fetal en tres categorías. Así se pueden establecer medidas oportunas antes que se produzcan daños irreversibles enel feto o en el peor de los casos la muerte fetal. Rev.cienc.biomed. 2015;6(1):170-178
Consideraciones bioéticas en tumores de cabeza y cuello
Authors: Osorio Anaya Steven , Villegas González Juliana , Morales Valdés Lady Johana 
Published: January 2021

Los carcinomas de cabeza y cuello (CCC) son tumores con elevada morbilidad y mortalidad, que causan un deterioro significativo de la calidad de vida en los pacientes con adversas repercusiones familiares y sociales. La mayoría de los pacientes consultan en estadios localmente avanzados y según la localización y compromiso, el pronóstico de vida sin tratamiento puede llegar a ser desalentador. Los tratamientos no están libres de consecuencias adversas. Algunos pueden ser tan mutilantes y discapacitantes como la misma enfermedad. El abordaje siempre debe ser integral y multidisciplinario con inmensa claridad de la connotación humana del paciente y sus familiares. Se deben ofrecer diferentes opciones de manejo, que buscarán la conservación o recuperación en la mejor medida posible de la calidad de vida. Debe evitarse la iatrogenia y los tratamientosexcesivos por el impacto adverso. Dilucidarse el riesgo al suicidio, la expectativa de vida y la oportunidad real de mejoría con la intervención propuesta. Rev.cienc.biomed. 2015;6(1):179-182
Coplanar Waveguide-fed UWB Slotted Antenna with Notched-band Performance
Authors: Aissaoui Djelloul , Chaabane Abdelhalim , Boualleg Ahcene , Guerroui Mohammed 
Published: January 2021

Compact coplanar waveguide Ultra-wideband (UWB) monopole antenna with band notched characteristics is presented in this paper. The band rejection is achieved by etching a circular slot on the radiating patch. The antenna is printed on the FR4-Epoxy substrate with overall dimensions of 23.5 × 31 × 1.5 mm3. The measured results indicate that the antenna operates in the frequency range from 1.76 to 11.07 GHz and rejects the band 2.42 to 5.37 GHz with an acceptable measured input impedance over the whole operating frequency bandwidth. Furthermore, the simulated results indicate that the antenna exhibits stable radiation patterns with appreciable gain and efficiency over the whole operating band except at the notched-band. Accordingly, this antenna provides a good solution for wireless communication systems with good characteristics.
Автоматизована система контролю промислових викидів
Authors: Мелконова І.В. , Романченко Ю.А. , Співак О.М. 
Published: January 2021

Моніторинг у галузі охорони атмосферного повітря проводиться з метою отримання, збирання, оброблення, збереження та аналізу інформації про рівень забруднення атмосферного повітря, оцінки та прогнозування його змін і ступеня небезпечності та розроблення науково обґрунтованих рекомендацій для прийняття рішень у галузі охорони атмосферного повітря У статті запропоновано комплексне технічне рішення щодо забезпечення автоматизованого моніторингу промислових викидів в атмосферу, що включає в себе технічні засоби вимірювання та інформаційні технології.
Types of Sentences Used by Male and Female Writers in Journal Article Abstracts
Authors: Willem Saragih  , Christine Hutajulu  
Published: January 2021

This study analyzed the types of sentences used in the Abstracts of Journal Articles written by 10 Female and 10 Male fully sourced from the Book Program of The First Annual International Seminar UNIMED Medan: November 19, 2016. Of the 195 sentences, 102 of which were written by females, and 92 by Males, all types of sentences are present. The occurrence of the types of sentence used by Females is Simple Sentence (50.1%), Complex Sentence (37.1%), Complex - Compound Sentence (6.8%), and Compound Sentence (4.9%). By Males, Simple Sentence is (50.%), Complex Sentence (41%), Compound Sentence (5.4%) and Complex- Compound Sentence (3.3%). Thus, this proves that the frequency is only different in Complex-Compound, i.e. by Females in the third place, but by Males in the fourth and Compound in the third. Overall, it can be concluded that gender has no relation with sentence types.
Stereotactic Body Radiotherapy Is Effective in Modifying the Tumor Genome and Tumor Immune Microenvironment in Non-Small Cell Lung Cancer or Lung Metastatic Carcinoma
Authors: Zhou Pu , Chen Diangang , Zhu Bo , Chen Wei , Xie Qichao , Wang Yali , Tan Qiulin , Yuan Bibo , Zuo Xuejiao , Huang Changlin , Zhu Hongfan , Li Guanghui 
Published: January 2021

Background and PurposeTo directly reveal the change in genome mutation, RNA transcript of tumor cells, and tumor microenvironment (TME) after stereotactic body radiotherapy (SBRT) in paired human lung tumor specimens.Materials and MethodsPaired tumor samples were collected from 10 patients with non-small cell lung cancer (NSCLC) or lung metastatic carcinoma within a week before and after SBRT. DNA and RNA of tumor tissues was extracted from the paired samples. Whole-exome and RNA sequencing assays were performed by next-generation sequencing. Gene mutation, genomic expression, T-cell receptor (TCR) repertoire, and profiling of tumor-infiltrating immune cells were analyzed through bioinformatics analysis in paired tumor samples. CD8+ T-cell infiltration and PD-L1 expressions were detected by immunostaining in tumor tissues.ResultsThe diversity of TCR repertoire and PD-L1 expression increased significantly in the TME, and the most enriched term of the gene ontology analysis was the immune response gene after receiving SBRT. SBRT induced neo-mutation of genes in tumor cells but did not increase tumor mutation burden in tumor tissues. TME displayed complex immune cell changes and infiltration and expression of immune-regulating factors such as C-X-C motif chemokine (CXCL) 10, CXCL16, interferons (IFNs), and IFN receptors. CD8+ T-cells in tumor tissues did not improve significantly after SBRT while the infiltrating TH1 and TH2 cells decreased remarkably.ConclusionSBRT improved the TCR repertoire diversity and PD-L1 expression in the TME and induced neo-mutation of genes in tumor cells but did not increase CD8+ T-cell infiltration and IFN expression in the tumor tissue within a week.
A Novel Scale for Assessment of Stroke Severity at Symptom Onset: Correlation With Neurological Deterioration and Outcome
Authors: Li Qi , Deng Lan , Huang Cheng , Zhang Wen-Yu , Zou Ning , Cao Du , Wei Xiao , Qin Xin-Yue 
Published: January 2021

Objective: To propose a novel scale for the assessment of stroke severity at symptom onset and to investigate whether it is associated with ultra-early neurological deterioration (UND) and functional outcomes.Methods: The Chongqing Stroke Scale (CQSS) was constructed based on key aspects of history, emphasizing language, motor function, and level of consciousness to yield a total 0–11 scale. The diagnostic performance of the CQSS was assessed in 215 ischemic stroke patients between June 2017 and October 2017 in a tertiary hospital. Patients were included if they presented within 24 h after onset of symptoms and they or their witness can recall the scenario at symptom onset. UND was defined as an increase ≥2 points on the CQSS between symptom onset and admission. Functional outcomes were assessed using the 3-month modified Rankin scale. The correlation between the CQSS score and baseline National Institutes of Health Stroke Scale (NIHSS) score was assessed. The sensitivity, specificity, and positive and negative predictive values of CQSS for the outcomes were calculated. Logistic regression was used to test the association between the CQSS score and functional outcomes.Results: A total of 215 patients with available CQSS scores were included. Baseline CQSS scores at symptom onset were correlated with the admission NIHSS score (r = 0.56, p &lt; 0.001) and functional outcome at 3 months (r = 0.47, p &lt; 0.001). Baseline CQSS ≥ 6 was an independent predictor of functional outcome at 3 months (odds ratio, 12.61; 95% confidence interval 5.68–27.97, p &lt; 0.001). UND was observed in 20 (9.30%) patients. The 90-day mortality was significantly higher in patients with UND than those without UND (25.0 vs. 8.2%, p &lt; 0.001). After adjusting for age, admission systolic blood pressure, hypertension, and diabetes, UND independently predicted poor functional outcome in the multivariate logistic regression model (odds ratio, 9.69; 95% confidence interval 3.19–29.45, p &lt; 0.001).Conclusions: The newly developed CQSS is a simple and easy-to-perform scale that allows a quantitative evaluation of the stroke severity at symptom onset and an assessment of UND before hospital admission. It is associated with NIHSS and predicts functional outcome in patients with acute ischemic stroke.
Adjuvant Radiotherapy Improved Survival in Stage I to II Low-Grade Endometrial Stromal Sarcoma: A Retrospective Study of 152 Cases
Authors: Wang Wenhui , Sun Shuai , Miao Zheng , Hou Xiaorong , Zhang Fuquan , Hu Ke 
Published: January 2021

ObjectiveLow-grade endometrial stromal sarcoma (LG-ESS) is a rare gynecological tumor. Whether adjuvant radiotherapy benefits survival in patients with resected early-stage ESS remains controversial. This study was designed to explore the role of adjuvant radiotherapy in stage I to II LG-ESS.MethodsWe retrospectively reviewed patients with stage I to II LG-ESS in our center from Jan. 1998 to Feb. 2018. All patients underwent a total hysterectomy and postoperative radiotherapy was administrated based on clinical and pathological characteristics.ResultsA total of 152 patients with stage I to II resected LG-ESS were included. Forty patients received adjuvant radiotherapy (RT group) while 112 patients did not receive adjuvant radiotherapy (no RT group). The baseline characteristics of the two groups were comparable, except that the proportion of stage II patients in the RT group was higher than that in the no RT group (32.5% vs. 11.6%, in RT vs. no RT groups, respectively; p = 0.003). For both patient groups, median overall survival was not reached. The median disease-free survival (DFS) was 144 months. Radiotherapy was associated with significantly improved DFS (92 months vs. not reached in RT vs. no RT groups, respectively; p = 0.008) and pelvic failure-free survival (PFFS) (92 months vs. not reached in RT vs. no RT groups, respectively; p=0.004). Subgroup analysis revealed that RT benefited survival most among patients with stage IB to IIB disease. Adjuvant radiotherapy significantly reduced the pelvic recurrence rate (10.0%, 4/40 vs. 28.6%, 32/112, p = 0.018). No radiotherapy-induced grade 4 to 5 toxicity was observed.ConclusionFor patients with stage I to II LG-ESS, adjuvant radiotherapy showed significant improvement in DFS and PFFS with tolerable adverse effects, especially in patients with stage IB to IIB disease.
Equity at the Ballot Box: Health as a Resource for Political Participation Among Low-Income Workers in Two United States Cities
Authors: McGuire Cydney M. , Gollust Sarah E. , De Marco Molly , Durfee Thomas , Wolfson Julian , Caspi Caitlin E. 
Published: January 2021

Objective: The purpose of this study is to identify health resources associated with propensity to vote at the local-level among low-wage workers in two United States. cities. Literature confirms individuals of lower income have a lower propensity of turning out to vote, yet few studies have focused on low-income populations to identify the variation in factors associated with voting within this group. Furthermore, few studies have investigated health and voter turnout at the local-level. In this study, we examine factors related to political participation at the local-level within a low-wage sample, examine mental, physical, behavioral, and social health and their association with voter turnout, and assess if these relationships differ by city.Methods: We use cross-sectional survey data from a sample of 974 low-wage workers in Minneapolis, MN and Raleigh, NC. We computed descriptive statistics and employed a logistic regression to predict their likelihood of local voter turnout, with the key independent variables being health resources, such as self-rated health, body mass index (BMI), mental disability, smoking status, and health insurance status. We employed a logistic regression fully interacted with a city indicator variable to assess if these associations differed by city.Results: In both cities, less than 50 percent of respondents reported voting in the last election for mayor or city council. About three-quarters of the sample reported food or housing insecurity and the majority of respondents reported utilizing some government assistance, such as supplemental nutrition programs. BMI greater than 30 was significantly associated with lower likelihood of voter turnout compared to those of lower BMI status (marginal effect = −0.10, p = 0.026). Never smoking or quitting was significantly associated with higher likelihood of voter turnout compared to those who reported being a current smoker (marginal effect = 0.10, p = 0.002). Those with health insurance were significantly more likely to report voting compared to those without any insurance (marginal effect = 0.10, p = 0.022). These results did not significantly differ by city.Conclusions: Our research suggests low-wage workers face significant health burdens which may impact their propensity to vote at the local-level, and these associations do not significantly vary by city despite demographic and political differences between two jurisdictions.
HIIT Models in Addition to Training Load and Heart Rate Variability Are Related With Physiological and Performance Adaptations After 10-Weeks of Training in Young Futsal Players
Authors: Campos Fernando de Souza , Borszcz Fernando Klitzke , Flores Lucinar Jupir Forner , Barazetti Lilian Keila , Teixeira Anderson Santiago , Hartmann Nunes Renan Felipe , Guglielmo Luiz Guilherme Antonacci 
Published: January 2021

IntroductionThe present study aimed to investigate the effects of two high-intensity interval training (HIIT) shuttle-run-based models, over 10 weeks on aerobic, anaerobic, and neuromuscular parameters, and the association of the training load and heart rate variability (HRV) with the change in the measures in young futsal players.MethodsEleven young male futsal players (age: 18.5 ± 1.1 years; body mass: 70.5 ± 5.7 kg) participated in this study. This pre-post study design was performed during a typical 10 weeks training period. HIIT sessions were conducted at 86% (HIIT86; n = 6) and 100% (HIIT100; n = 5) of peak speed of the FIET. Additionally, friendly and official matches, technical-tactical and strength-power training sessions were performed. Before and after the training period, all players performed the FIET, treadmill incremental, repeated sprint ability (RSA), sprint 15-m, and vertical jump tests (CMJ and SJ), and the HRV was measured. Training load (TL) was monitored using the session rating of perceived effort. Data analysis was carried out using Bayesian inference methods.ResultsThe HIIT86 model showed clear improvements for the peak oxygen uptake (VO2peak), peak speed in the treadmill incremental test, first and second ventilatory thresholds, RSA best and mean times, CMJ, and SJ. The HIIT100 model presented distinct advances in VO2peak, peak speed in the treadmill incremental test, RSA mean time, and CMJ. Between HIIT models comparisons showed more favorable probabilities of improvement for HIIT86 than HIIT100 model in all parameters. TL data and HIIT models strongly explained the changes in the RSA mean and best times (R2 = 0.71 and 0.87, respectively), as well as HRV changes, and HIIT models explained positively VO2peak changes (R2 = 0.72). All other changes in the parameters were low to moderately explained.ConclusionThe HIIT86 proved to be more effective for improving aerobic, RSA, and neuromuscular parameters than HIIT100 during a typical 10-week futsal training period. So, strength and conditioning specialists prescribing shuttle-run intermittent exercises at submaximal intensities can manage the individual acceleration load imposed on athlete increasing or decreasing either the set duration or the frequency of change of direction during HIIT programming.
Frequency of Retinoblastoma at Lady Reading Hospital, Peshawar, Pakistan
Authors: Iqbal Zafar , Saeed Tariq Muhammad 
Published: January 2021

Aim: To ascertain the demographics, clinical features, and treatment options for children with retinoblastoma. Methods: This was a hospital-based cohort study of all children with retinoblastoma presenting from 1 January 2008 to 31 December 2008. Demographic data, presenting features, family history, and findings identified during examination were recorded for each patient. The tumours were classified using the Reese- Ellsworth classification system. Documentation of the tumours included examination under anesthesia, ultrasound B- scan, and computed tomography scan as well as histopathological reporting of enucleated eyes.Results: Twenty seven new patients with retinoblastoma were identified and 36 eyes were affected, with a bilaterality rate of 33%. The frequency was 4.1, with a bimodal peak of presentation of younger than 1 yearand 4 years. The mean age at diagnosis was 3.2 years (SD, 2.5 years; range, 3 months to 8 years). Most of the patients were boys, (59%) and most were in the age range of 1 to 5 years (66%). There was a male preponderance (5:1) amongst patients younger than 1 year and the male to female ratio was equal (1:1) in the 1 to 5 years age range. Leukocoria was the main presentation in 38% of eyes and 19% presented with proptosis. Enucleation/exenteration was performed for 17 unilateral eyes (94%) and 5 bilateral eyes (27%) with group V disease. Groups I and II tumours (n = 1 and n = 7 for unilateral and bilateral eyes, respectively) were treated conservatively with cryotherapy or chemotherapy alone or in combination. The commonest treatment for bilateral disease was enucleation of 1 eye and chemotherapy for the fellow eye (22%). Radiotherapy was advised for patients with histopathological evidence of optic nerve involvement (25%).Conclusions: Retinoblastoma usually affects infants and children younger than 5 years, with no sexual or racial predilection. One-third of patients demonstrate bilaterality, with leukocoria as the commonest presenting feature and proptosis as a feature of late presentation. In bilateral retinoblastoma, primary enucleation of one eye with conservative chemotherapy and/or cryotherapy of the fellow eye is advocated.
Effect of Desonide 0.25% Ophthalmic Solution on Central Corneal Thickness and Intraocular Pressure of Patients with Allergic Conjunctivitis
Authors: Sahin Ozlem Gurses 
Published: January 2021

Aim: To evaluate whether a significant difference exists between the initial and final mean central corneal thickness that might affect Goldmann applanation tonometer recordings of patients with allergic conjunctivitis treated with desonide 0.25% ophthalmic solution, and to determine the effect of desonide on intraocular pressure by using adjusted intraocular pressure values.Methods: This double-blind randomised placebo-controlled trial enrolled 30 patients (60 eyes) with allergic conjunctivitis. Patients were randomly assigned to receive desonide to 1 eye (study eye) and preservative-free tear supplement (Tears Naturale Free®) to the other eye (control eye) 3 times daily for 3 weeks. Goldmann applanation tonometry and central corneal thickness of both eyes were recorded on the day of presentation and 3 weeks later.Results: Regression of itching, tearing, conjunctival hyperaemia, and tarsal conjunctival papillary reaction were noted in the study eyes after 3 weeks of treatment. The control eyes showed mild regression of pruritis, tearing, conjunctival hyperaemia, and tarsal conjunctival papillary reaction after 3 weeks. There was a significant difference between the initial and final mean central corneal thickness values for the study eyes (p = 0.003). There were no statistically significant differences between the initial and final mean values of Goldmann applanation tonometry and adjusted intraocular pressure for the study eyes. No statistically significant differences were found between the initial and final mean values of any of the parameters for the control eyes.Conclusion: Inflammation-induced increase in central corneal thickness of patients with allergic conjunctivitis treated with desonide showed statistically significant regression. However, this regression did not significantly affect Goldmann applanation tonometry and adjusted intraocular pressure values of the treated eyes.
Detection of Senile Scleral Plaque after Head Trauma
Authors: Guigui Sarah , Lifshitz Tova , Baidousi Amjad , Yagev Ronit , Levy Jaime 
Published: January 2021

Senile scleral plaques are late onset ocular calcifications, and are usually detected incidentally on orbital computed tomography scan following trauma. This report is of 4 elderly patients with senile scleral plaques who were admitted to the emergency room following trauma to the head. A head/orbital computed tomography scan was performed as part of the routine examination. In all 4 patients, computed tomography scan revealed a clear retina and no scleral perforation or foreign body intrusion, but bilateral radiodense areas were located anterior to the insertion of the horizontal rectus muscles. These areas were diagnosed as senile scleral plaques. Even though these ocular calcifications are benign, they have important prognostic implications, and should therefore be identified correctly and not confused with other ocular pathologies.