bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of the Musca domestica Salivary Gland Hypertrophy Virus on Food Consumption in Its Adult Host, the Common House Fly (Diptera: Muscidae)
Authors: Rachimi Suzanna , Burand John P , Geden Chris , Stoffolano John G 
Published: January 2021

Abstract
The Musca domestica salivary gland hypertrophy virus (MdSGHV) substantially enlarges the house fly’s salivary glands and prevents or delays ovarian development in its adult host, but the effect that MdSGHV has on the house fly’s food consumption is currently unknown. Using house flies from a laboratory-reared colony, we evaluated the effect of MdSGHV infection on food consumption over a 7-d period. Both treatment (virus-infected) and control (saline-injected) flies were provided with a choice of 8% sucrose solution and 4% powdered milk solution to determine food preferences. Quantities of each solution consumed were measured every 24 h for each fly to measure food consumptions. Infected house flies were shown to consume less overall of both solutions than house flies injected with saline. The largest consumption discrepancy was seen between female house flies. Healthy female flies with developing ovaries continued to consume a sugar and protein diet, whereas infected female flies fed predominantly on a sugar diet. Additionally, infected male and female flies consumed significantly lower quantities of protein and sucrose than control flies. This suggests that MdSGHV has a negative consumption effect (e.g., hunger, starvation) on its host. Thus, differences in food consumption of infected and control flies probably represent differences in the nutritional requirements of flies resulting from viral infection.
High Proportion of Unfed Larval Blacklegged Ticks, Ixodes scapularis (Acari: Ixodidae), Collected From Modified Nest Boxes for Mice
Authors: Larson R T , Bron G M , Lee X , Paskewitz S M 
Published: January 2021

Abstract
The blacklegged tick, Ixodes scapularis Say, is the primary vector of several tick-borne pathogens, including those causing Lyme disease and babesiosis, in the eastern United States and active collection methods for this species include dragging or wild animal sampling. Nest boxes targeting mice may be an alternative strategy for the surveillance and collection of immature I. scapularis feeding on these hosts and would be much safer for animals compared to small mammal trapping. We constructed double-walled insulated nest boxes (DWINs) with collection tubes mounted below the nesting chamber and deployed eleven in southern Wisconsin from June until September of 2020. The DWINs were occupied by Peromyscus spp. and birds (wren species, Troglodytidae family). We collected 192 ticks from collection tubes, all of which were identified as either I. scapularis (95%) or Dermacentor variabilis Say (Acari: Ixodidae) (5%). Only 12% (21/182) and 20% (2/10) of I. scapularis and D. variabilis were blood-fed, respectively. The high proportion of unfed ticks found in collection tubes may be due to grooming by hosts inside the nest boxes. Alternatively, immature ticks may have climbed trees and entered the DWIN seeking a host. Results suggest that nest boxes could be a tool for finding ticks in areas of low density or at the leading edge of invasion, when small mammal trapping or drag sampling is not feasible.
A study of continuous vector representations for theorem proving
Authors: PurgaŁ StanisŁaw , Parsert Julian , Kaliszyk Cezary 
Published: January 2021

Abstract
Applying machine learning to mathematical terms and formulas requires a suitable representation of formulas that is adequate for AI methods. In this paper, we develop an encoding that allows for logical properties to be preserved and is additionally reversible. This means that the tree shape of a formula including all symbols can be reconstructed from the dense vector representation. We do that by training two decoders: one that extracts the top symbol of the tree and one that extracts embedding vectors of subtrees. The syntactic and semantic logical properties that we aim to preserve include both structural formula properties, applicability of natural deduction steps and even more complex operations like unifiability. We propose datasets that can be used to train these syntactic and semantic properties. We evaluate the viability of the developed encoding across the proposed datasets as well as for the practical theorem proving problem of premise selection in the Mizar corpus.
The PAU Survey: an improved photo-zsample in the COSMOS field
Authors: Alarcon Alex , Gaztanaga Enrique , Eriksen Martin , Baugh Carlton M , Cabayol Laura , Casas Ricard , Carretero Jorge , Castander Francisco J , De Vicente Juan , Fernandez Enrique , Garcia-Bellido Juan , Hildebrandt Hendrik , Hoekstra Henk , Joachimi Benjamin , Manzoni Giorgio , Miquel Ramon , Norberg Peder , Padilla Cristobal , Renard Pablo , Sanchez Eusebio , Serrano Santiago , Sevilla-Noarbe Ignacio , Siudek Malgorzata , Tallada-Crespí Pau 
Published: January 2021

ABSTRACTWe present – and make publicly available – accurate and precise photometric redshifts in the ACS footprint from the COSMOS field for objects with iAB ≤ 23. The redshifts are computed using a combination of narrow-band photometry from PAUS, a survey with 40 narrow bands spaced at $100\,\mathring{\rm A}$ intervals covering the range from 4500 to $8500\,\mathring{\rm A}$, and 26 broad, intermediate, and narrow bands covering the UV, visible and near-infrared spectrum from the COSMOS2015 catalogue. We introduce a new method that models the spectral energy distributions as a linear combination of continuum and emission-line templates and computes its Bayes evidence, integrating over the linear combinations. The correlation between the UV luminosity and the O ii line is measured using the 66 available bands with the zCOSMOS spectroscopic sample, and used as a prior which constrains the relative flux between continuum and emission-line templates. The flux ratios between the O ii line and Hα, Hβ and $\mathrm{O\,{\small III}}$ are similarly measured and used to generate the emission-line templates. Comparing to public spectroscopic surveys via the quantity Δz ≡ (zphoto − zspec)/(1 + zspec), we find the photometric redshifts to be more precise than previous estimates, with σ68(Δz) ≈ (0.003, 0.009) for galaxies at magnitude iAB ∼ 18 and iAB ∼ 23, respectively, which is three times and 1.66 times tighter than COSMOS2015. Additionally, we find the redshifts to be very accurate on average, yielding a median of the Δz distribution compatible with |median(Δz)| ≤ 0.001 at all redshifts and magnitudes considered. Both the added PAUS data and new methodology contribute significantly to the improved results. The catalogue produced with the technique presented here is expected to provide a robust redshift calibration for current and future lensing surveys, and allows one to probe galaxy formation physics in an unexplored luminosity-redshift regime, thanks to its combination of depth, completeness, and excellent redshift precision and accuracy.
Searching for signatures of chaos in γ-ray light curves of selected Fermi-LAT blazars
Authors: Ostapenko O , Tarnopolski M , Żywucka N , Pascual-Granado J 
Published: January 2021

ABSTRACT
Blazar variability appears to be stochastic in nature. However, a possibility of low-dimensional chaos was considered in the past, but with no unambiguous detection so far. If present, it would constrain the emission mechanism by suggesting an underlying dynamical system. We rigorously searched for signatures of chaos in Fermi-Large Area Telescope light curves of 11 blazars. The data were comprehensively investigated using the methods of nonlinear time-series analysis: phase-space reconstruction, fractal dimension, and maximal Lyapunov exponent (mLE). We tested several possible parameters affecting the outcomes, in particular the mLE, in order to verify the spuriousness of the outcomes. We found no signs of chaos in any of the analysed blazars. Blazar variability is either truly stochastic in nature or governed by high-dimensional chaos that can often resemble randomness.
The impact of asymmetric neutrino emissions on nucleosynthesis in core-collapse supernovae II – progenitor dependences
Authors: Fujimoto Shin-ichiro , Nagakura Hiroki 
Published: January 2021

ABSTRACT
We investigate the impact of asymmetric neutrino emissions on explosive nucleosynthesis in core-collapse supernovae (CCSNe) of progenitors with a mass range of 9.5–25 M⊙. We perform axisymmetric, hydrodynamic simulations of the CCSN explosion with a simplified neutrino transport, in which anticorrelated dipolar emissions of νe and ${\bar{\nu }}_{\rm e}$ are imposed. We then evaluate abundances and masses of the CCSN ejecta in a post-processing manner. We find that the asymmetric ν-emission leads to the abundant ejection of p- and n-rich matter in the high-νe and -${\bar{\nu }}_{\rm e}$ hemispheres, respectively. It substantially affects the abundances of the ejecta for elements heavier than Ni regardless of progenitors, although those elements lighter than Ca are less sensitive. Based on these results, we calculate the initial mass function-averaged abundances of the CCSN ejecta with taking into account the contribution from Type Ia SNe. For $m_{\rm asy} = 10/3{{\ \rm per\ cent}}$ and $10{{\ \rm per\ cent}}$, where masy denotes the asymmetric degree of the dipole components in the neutrino emissions, the averaged abundances for elements lighter than Y are comparable to those of the solar abundances, whereas those of elements heavier than Ge are overproduced in the case with $m_{\rm asy} \ge 30{{\ \rm per\ cent}}$. Our result also suggests that the effect of the asymmetric neutrino emissions is imprinted in the difference of abundance ratio of [Ni/Fe] and [Zn/Fe] between the high-νe and -${\bar{\nu }}_{\rm e}$ hemispheres, indicating that the future spectroscopic X-ray observations of a CCSN remnant will bring evidence of the asymmetric neutrino emissions if exist.
Core-collapse, superluminous, and gamma-ray burst supernova host galaxy populations at low redshift: the importance of dwarf and starbursting galaxies
Authors: Taggart K , Perley D A 
Published: January 2021

ABSTRACT
We present a comprehensive study of an unbiased sample of 150 nearby (median redshift, z = 0.014) core-collapse supernova (CCSN) host galaxies drawn from the All-Sky Automated Survey for Supernovae (ASAS-SN) for direct comparison to the nearest long-duration gamma-ray burst (LGRB) and superluminous supernova (SLSN) hosts. We use public imaging surveys to gather multiwavelength photometry for all CCSN host galaxies and fit their spectral energy distributions (SEDs) to derive stellar masses and integrated star formation rates (SFRs). CCSNe populate galaxies across a wide range of stellar masses, from blue and compact dwarf galaxies to large spiral galaxies. We find 33$^{+4}_{-4}$ per cent of CCSNe are in dwarf galaxies (M* &lt; 109 M⊙) and 2$^{+2}_{-1}$ per cent are in dwarf starburst galaxies [specific star formation rate (sSFR) &gt; 10−8 yr−1]. We reanalyse low-redshift SLSN and LGRB hosts from the literature (out to z &lt; 0.3) in a homogeneous way and compare against the CCSN host sample. The relative SLSN to CCSN supernova rate is increased in low-mass galaxies and at high sSFRs. These parameters are strongly covariant and we cannot break the degeneracy between them with our current sample, although there is some evidence that both factors may play a role. Larger unbiased samples of CCSNe from projects such as ZTF and LSST will be needed to determine whether host-galaxy mass (a proxy for metallicity) or sSFR (a proxy for star formation intensity and potential IMF variation) is more fundamental in driving the preference for SLSNe and LGRBs in unusual galaxy environments.
Successive occurrences of quasi-circular ribbon flares in a fan-spine-like configuration involving hyperbolic flux tube
Authors: Mitra Prabir K , Joshi Bhuwan 
Published: January 2021

ABSTRACT
We present a comprehensive analysis of the formation and the evolution of a fan-spine-like configuration that developed over a complex photospheric configuration where dispersed negative polarity regions were surrounded by positive polarity regions. This unique photospheric configuration, analogous to the geological ‘atoll’ shape, hosted four homologous flares within its boundary. Computation of the degree of squashing factor (Q) maps clearly revealed an elongated region of high Q-values between the inner and outer spine-like lines, implying the presence of an hyperbolic flux tube (HFT). The coronal region associated with the photospheric atoll configuration was distinctly identified in the form of a diffused dome-shaped bright structure directly observed in Extreme Ultraviolet (EUV) images. A filament channel resided near the boundary of the atoll region. The activation and eruption of flux ropes from the filament channel led to the onset of four eruptive homologous quasi-circular ribbon flares within an interval of ≈11 h. During the interval of the four flares, we observed continuous decay and cancellation of negative polarity flux within the atoll region. Accordingly, the apparent length of the HFT gradually reduced to a null-point-like configuration before the fourth flare. Prior to each flare, we observed localized brightening beneath the filaments which, together with flux cancellation, provided support for the tether-cutting model of solar eruption. The analysis of magnetic decay index revealed favourable conditions for the eruption, once the pre-activated flux ropes attained the critical heights for torus instability.
Modelled 3D distribution of OH/IR stars in the Galactic disc
Authors: Uno Y , Imai H , Shinano K , Qiao H-H , Dawson J R , Breen S L , Gómez J F 
Published: January 2021

ABSTRACT
We have modelled the 3D distribution of OH/IR stars in the Galactic plane, traced by 1612 MHz OH maser sources with classic double horned spectral profiles. We statistically analysed over 700 maser sources detected by the HI/OH/Recombination line survey of the Milky Way (THOR) and the Australia Telescope Compact Array interferometric follow-up observations of the Southern Parkes Large-Area Survey in Hydroxyl (SPLASH). With a simple model constructed from a classical density distribution of stars and luminosity functions of OH maser sources in the Galaxy, we estimate the scale height, or the half thickness of the OH/IR star distribution along the Galactic disc to be 90–290 pc. The simple model also implies that there are ∼4000 OH/IR stars hosting 1612 MHz OH masers along the Galactic Plane. Therefore, next generation telescopes such as the Australian Square Kilometre Array Pathfinder (ASKAP) and SKA Phase 1 will detect about 80 per cent of such OH/IR stars in the Galaxy at a 10 mJy detection limit. Comparing the data of previously detected circumstellar 1612 MHz OH maser sources with those of THOR and SPLASH, the maser source lifetime is estimated to be ∼300 yr. This is likely a lower limit, since non-detections of masers in some cases could be affected by the flux variation of the maser source.
A combined analysis of the H0 late time direct measurements and the impact on the Dark Energy sector
Authors: Di Valentino Eleonora 
Published: January 2021

ABSTRACT
We combine 23 Hubble constant measurements based on Cepheids-SN Ia, TRGB-SN Ia, Miras-SN Ia, Masers, Tully Fisher, Surface Brightness Fluctuations, SN II, Time-delay Lensing, Standard Sirens and γ-ray Attenuation, obtaining our best optimistic H0 estimate, that is H0 = 72.94 ± 0.75 km s–1 Mpc–1 at 68 per cent CL. This is in 5.9σ tension with the ΛCDM model, therefore we evaluate its impact on the extended Dark Energy cosmological models that can alleviate the tension. We find more than 4.9σ evidence for a phantom Dark Energy equation of state in the wCDM scenario, the cosmological constant ruled out at more than 3σ in a w0waCDM model and more than 5.7σ evidence for a coupling between Dark Matter and Dark Energy in the IDE scenario. Finally, we check the robustness of our results; and we quote two additional combinations of the Hubble constant. The ultra-conservative estimate, H0 = 72.7 ± 1.1 km s–1 Mpc–1 at 68 per cent CL, is obtained removing the Cepheids-SN Ia and the Time-Delay Lensing based measurements, and confirms the evidence for new physics.
Small-molecule inhibitors of histone deacetylase improve CRISPR-based adenine base editing
Authors: Shin Ha Rim , See Ji-Eun , Kweon Jiyeon , Kim Heon Seok , Sung Gi-Jun , Park Sojung , Jang An-Hee , Jang Gayoung , Choi Kyung-Chul , Kim Inki , Kim Jin-Soo , Kim Yongsub 
Published: January 2021

AbstractCRISPR-based base editors (BEs) are widely used to induce nucleotide substitutions in living cells and organisms without causing the damaging DNA double-strand breaks and DNA donor templates. Cytosine BEs that induce C:G to T:A conversion and adenine BEs that induce A:T to G:C conversion have been developed. Various attempts have been made to increase the efficiency of both BEs; however, their activities need to be improved for further applications. Here, we describe a fluorescent reporter-based drug screening platform to identify novel chemicals with the goal of improving adenine base editing efficiency. The reporter system revealed that histone deacetylase inhibitors, particularly romidepsin, enhanced base editing efficiencies by up to 4.9-fold by increasing the expression levels of proteins and target accessibility. The results support the use of romidepsin as a viable option to improve base editing efficiency in biomedical research and therapeutic genome engineering.
Dorsal Root Entry Zone Lesioning for Brachial Plexus Avulsion: A Comprehensive Literature Review
Authors: Gebreyohanes Axumawi Mike Hailu , Ahmed Aminul Islam , Choi David 
Published: January 2021

Abstract
Dorsal root entry zone (DREZ) lesioning is a neurosurgical procedure that aims to relieve severe neuropathic pain in patients with brachial plexus avulsion by selectively destroying nociceptive neural structures in the posterior cervical spinal cord. Since the introduction of the procedure over 4 decades ago, the DREZ lesioning technique has undergone numerous modifications, with a variety of center- and surgeon-dependent technical differences and patient outcomes. We have reviewed the literature to discuss reported methods of DREZ lesioning and outcomes.
Use of Continuous Electrical Impedance Measurement for Accurate Nerve Block in Rabbits
Authors: Ootaki Chiyo , Kobayashi Yo , Koyama Yuki 
Published: January 2021

Abstract

Objective
To perform an effective and safe nerve block, the needle must be placed near the target nerve while avoiding nerve damage. Our objective was to conduct an animal study to determine whether changes in electrical impedance (EI) could be used to guide the needle and achieve a safe and accurate nerve block.

Methods
We measured the EI of rabbit tissues during ultrasound-guided sciatic nerve block using a bipolar needle via the in-plane needle approach. The EI values and needle track on the ultrasound monitor were video-recorded. When there was a change in the EI, the needle advancement was stopped, and a stained anesthetic was injected. Subsequently, the animals were euthanized, and the anesthetic-stained tissue was examined via dissection, while the other tissue was preserved at –80°C for microscopic analysis.

Results
The EI remained stable as the needle advanced through the muscle (extraneural); however, it markedly decreased when the needle tip contacted the nerve or slightly punctured the epineurium (paraneural). The mean extra- and paraneural EIs were 4.92 ± 1.31 kΩ (range, 2.39–9.67 kΩ) and 2.86 ± 0.96 kΩ (range, 1.66–5.13 kΩ), respectively. Examination of the dissections and cryostat sections showed anesthetic delivery around the nerve.

Conclusions
EI values differed between extra- and paraneural sites, and monitoring these values allowed prediction of the needle tip location with respect to the target nerve. Real-time EI measurement could improve the nerve block.
A Comparison of Genicular Nerve Blockade With Corticosteroids Using Either Classical Anatomical Targets vs Revised Targets for Pain and Function in Knee Osteoarthritis: A Double-Blind, Randomized Controlled Trial
Authors: Fonkoue Loïc , Steyaert Arnaud , Kouame Jean-Eric K , Bandolo Eric , Lebleu Julien , Fossoh Hermann , Behets Catherine , Detrembleur Christine , Cornu Olivier 
Published: January 2021

Abstract

Objective
Compare the effectiveness of genicular nerve blockade (GNB) using classical anatomical targets (CT) versus revised targets (RT) in patients suffering from chronic knee osteoarthritis pain.

Design
Double-blinded randomized controlled trial.

Setting
Pain medicine center of a teaching hospital.

Methods
We randomly assigned 55 patients with chronic knee osteoarthritis pain to receive a GNB (using a fluid mixture of 2 mL: lidocaine 1% + 20 mg triamcinolone) with either classical targets (CT-group, n = 28) or revised targets (RT-group, n = 27). Numeric rating pain scale (NRS), Oxford knee score (OKS), Western Ontario and McMaster Universities osteoarthritis index score (WOMAC), Quantitative analgesic questionnaire (QAQ) and global perceived effects were assessed at baseline, and at 1-hour, 24-hours, 1, 4, and 12 weeks post-intervention.

Results
The RT-group showed greater reduction in NRS mean score at 1-hour post-intervention (2.4 ± 2.1 vs 0.4 ± 0.9, 95% confidence interval (CI) [.0–.8] vs [1.6–3.2], P &lt; .001). The proportion of patients achieving more than 50% knee pain reduction was higher in the RT-group at each follow up interval, yet these differences were statistically significant only at 1-hour post intervention (82.1% [95% CI = 63.1–93.9] vs 100% [95% CI = 97.2–100] P = .02). Both protocols resulted in significant pain reduction and joint function improvement up to 12 weeks post-intervention.

Conclusions
The revised technique allowed more pain relief as well as greater proportion of successful responders at 1-hour post intervention. The large volume injected during therapeutic GNB could have compensated the lack of precision of the classical anatomical targets, mitigating differences in outcomes between both techniques.