bluuebunny/crossref_metadata_2025_split huggingface dataset:
GASTON BACHELARD AND JOSÉ AMÉRICO: A PLAYFUL GAME OF PHILOSOPHIZING
Authors: Bulcão Marly 
Published: November 2021

The purpose of this work is to make a rapprochement between José Américo Pessanha, a Brazilian thinker who taught through his lectures a personal philosophy, and Gaston Bachelard, a French philosopher of undeniable importance. Both of them, starting from a critique of tradition, renew the notions of reason and imagination. The development of this work will make it evident that, for both of them, it does not make sense at the present time to accept the idea of ​​a single, universal and timeless reason. They exalt, therefore, the character of historicity of reason which, in the course of its progress, is renewed, rectified, re-established, as well as establishes new truths. On the other hand, on the contrary to what the tradition wanted, the imagination can not be understood as a simulacrum of the perceived real, as this would lead to the overlook of it before the perception and the idea. The conclusion will finally show that the proposal of a new notion of reason and imagination will have repercussions on the conception of culture, revealing the importance of the reflections of Bachelard and José Américo for contemporaneity.
Keywords: Bachelard. José Américo. Reason. Imagination.
THE CONTRIBUTION OF SOCIAL SCIENCES TO A CRITICAL READING OF THE MEDIA
Authors: Ferreira Isabelle Azevedo , Silva Lara Lanny de Oliveira , Alves Rennata Kelly Muniz 
Published: November 2021

Understanding that Social Sciences are challenged to provide theoretical and practical tools for the development of educational research, this article proposes to comprehend the role of Social Sciences and its cooperation to the area of media education. In a society increasingly dominated by the media, it is fundamental to understand how school, in this context, is responding to the challenges emerged by technology, that is transforming the ways in which society evolves and as it also questions the role of the media in the present time and its power to constitute reality. Using the thematic delimitation expressed in theses and dissertations as references, the specific objective is to verify the thematic and theoretical recurrences, the methodology used for it, as well as the difficulties encountered in the research on the ways in which the school institution and the teachers draw upon media and information and communication technologies (ICTs) to stimulate a critical analysis of the relation between the media and power. The analysis will be made based on the abstracts of the works defended in Brazil from 2005 to 2015, available in the database of Capes (Sucupira Platform) and in the Brazilian Digital Library of Theses and Dissertations (BDTD). The methodology used to analyze the abstracts will be through the analysis of the content. The proposed result points to a balance of researches already produced, as well as new possibilities of the intercultural exchange between fields of distinct traditions such as social sciences, communication and education.
Keywords: Social Sciences. Communication. Education. Abstracts.
Turismo, mineração e desenvolvimento: relações complexas
Authors: Faria Diomira M.C.P. , De Freitas Neto Jorge Fernandes , Ferreira Jordana Romano 
Published: November 2021

Diante de um cenário onde duas atividades fazem uso dos recursos naturais de um território buscando se estabelecer através da premissa de contribuir para o seu desenvolvimento, surgiu a necessidade de analisar os diversos impactos econômicos e sociais causados pela atividade turística e de extração mineral, no município de Conceição do Mato Dentro – MG. De caráter exploratório, utilizando-se de dados secundários e de entrevistas com lideranças locais, os resultados do estudo mostraram que a mineração foi determinante para a expansão dos empregos e aumento do PIB municipal, embora seja responsável por danos sociais e ambientais. Cenários de longo prazo conferem ao turismo maior vantagem relativa comparado à mineração.
Tourism of events in Campos do Jordão: CJCVB strategies to attract events
Authors: Fedrizzi Valéria Luiza Pereira , Mendes Bruna de Castro , Schliemann Magda 
Published: November 2021

O objetivo desse artigo foi apresentar Campos do Jordão, situada no extremo leste do estado de São Paulo, como sendo uma cidade privilegiada pela sua posição estratégica, clima, fauna e flora. De toda sua oferta turística, analisou-se o segmento de eventos na cidade e seu fomento via captação realizada pelo Campos do Jordão e Região CVB (CJCVB), utilizando-se de uma metodologia amparada no programa exploratório-descritivo, baseando-se nos dados fornecidos pelo CJCVB, como também em pesquisa bibliográfica. A cidade conta com várias opções de espaços adequados para a operacionalização de eventos, bem como, a abundante oferta de leitos hoteleiros, para seus participantes, evidenciando-se a contribuição dessa entidade na geração de receita proveniente dos eventos captados e apoiados nos respectivos períodos (2006-2008, 2009, 2010, 2011, 2012, 2013, 2014 e 2015). Percebe-se uma mudança de perfil de eventos na cidade, pois além dos já consolidados eventos de negócios, a cidade tem captado também eventos esportivos, contando com suas áreas naturais, e esses eventos sediados no município destacam-se como uma oferta inovadora e criativa para melhorar os resultados econômicos e minimizar os efeitos da sazonalidade.
O setor hoteleiro na praia de Canoa Quebrada/CE: Processo de expansão urbana e turística
Authors: Siqueira Felipe de Souza , Urano Débora Goes , Pereira Raquel Maria Fontes do Amaral 
Published: November 2021

Este artigo discute a expansão da atividade turística na praia de Canoa Quebrada - Ceará, buscando entender suas implicações sobre o desenvolvimento do setor hoteleiro a partir das iniciativas pioneiras na década de 1970 até sua ampliação nos dias atuais. Seu foco principal é o setor hoteleiro, sua expansão e as transformações decorrentes do crescimento urbano e dos fluxos turísticos, abarcando as origens e as principais características desse setor, bem como a sua relação com a evolução da localidade. A operacionalização da pesquisa impôs a definição de um referencial teórico apropriado ao entendimento do processo de expansão da cidade e dos fluxos turísticos, de modo a propiciar a apreensão da totalidade dos elementos naturais e humanos definidores da realidade investigada. A análise dos processos locais relativos à expansão urbana e turística exigiu a sua articulação ao contexto regional e nacional, bem como a consulta à obras capazes de oferecer elementos acerca da realidade objeto da investigação, elucidando aspectos relacionados às origens e a evolução do setor hoteleiro, decorrentes de transformações sócio espaciais ocorridas em Canoa Quebrada.
Proteomic Analysis of the Colistin-resistant E. coli Clinical Isolate: Explorations of the Resistome
Authors: Sharma Divakar , Aswal Manisha , Ahmad Nayeem , Kumar Manish , Khan Asad U. 
Published: November 2021

Background:
Antimicrobial resistance is a worldwide problem after the emergence of
colistin resistance since it was the last option left to treat carbapenemase-resistant bacterial infections.
The mcr gene and its variants are one of the causes for colistin resistance. Besides mcr genes,
some other intrinsic genes are also involved in colistin resistance but still need to be explored.

Objective:
The aim of this study was to investigate differential proteins expression of colistin-resistant
E. coli clinical isolate and to understand their interactive partners as future drug targets.

Methods:
In this study, we have employed the whole proteome analysis through LC-MS/MS. The
advance proteomics tools were used to find differentially expressed proteins in the colistin-resistant
Escherichia coli clinical isolate compared to susceptible isolate. Gene ontology and STRING were
used for functional annotation and protein-protein interaction networks, respectively.

Results:
LC-MS/MS analysis showed overexpression of 47 proteins and underexpression of 74 proteins
in colistin-resistant E. coli. These proteins belong to DNA replication, transcription and translational
process; defense and stress related proteins; proteins of phosphoenol pyruvate phosphotransferase
system (PTS) and sugar metabolism. Functional annotation and protein-protein interaction
showed translational and cellular metabolic process, sugar metabolism and metabolite interconversion.

Conclusion:
We conclude that these protein targets and their pathways might be used to develop
novel therapeutics against colistin-resistant infections. These proteins could unveil the mechanism
of colistin resistance.
In Silico Prediction of Epitopes in Virulence Proteins of Mycobacterium ulcerans
for Vaccine Designing
Authors: Mohinani Taruna , Saxena Aditya , Singh Shoor Vir 
Published: November 2021

Background:
Mycobacterium ulcerans is the fundamental agent of the third most common Mycobacterial disease known as Buruli Ulcer (BU). It is an infection of the skin and soft tissue affecting the human population worldwide. Presently, the vaccine is not available against BU.

Objective:
This study aimed to investigate the vaccine potential of virulence proteins of M. ulcerans computationally.

Methods:
Chromosome encoded virulence proteins of Mycobacterium ulcerans strain Agy99 were selected, which were available at the VFDB database. These proteins were analyzed for their subcellular
localization, antigenicity, and human non-homology analysis. Ten virulence factors were finally chosen and analyzed for further study. Three-dimensional structures for selected proteins were predicted using Phyre2. B cell and T cell epitope analysis was done using methods available at Immune Epitope Database and Analysis Resource. Antigenicity, allergenicity, and toxicity analysis were also done to predict epitopes. Molecular docking analysis was done for T cell epitopes, those showing overlap with B cell epitopes.

Results:
Selected virulence proteins were predicted with B cell and T cell epitopes. Some of the selected proteins were found to be already reported as antigenic in other mycobacteria. Some of the
predicted epitopes also had similarities with experimentally identified epitopes of M. ulcerans and M. tuberculosis which further supported our predictions.

Conclusion :
In-silico approach used for the vaccine candidate identification predicted some virulence proteins that could be proved important in future vaccination strategies against this chronic disease. Predicted epitopes require further experimental validation for their potential use as peptide vaccines.
The Role of Aromatase Enzyme in Hormone Related Diseases and Plant-
Based Aromatase Inhibitors as Therapeutic Regimens
Authors: Akça Kevser Taban , Demirel Murside Ayşe , Süntar Ipek 
Published: November 2021

:
Medicinal plants have a long history of use as food and remedy in traditional and modern
societies. They have been used as herbal drugs and sources of novel bioactive compounds.
They provide a wide array of chemical compounds, many of which can not be synthesized via current
synthesis methods. Natural products may provide aromatase inhibitory activity through various
pathways and may act clinically effective for treating pathologies associated with excessive aromatase
secretion, including breast, ovarian, and endometrial cancers, endometriosis, uterine fibroid,
benign prostatic hyperplasia (BPH), prostate cancer, infertility, and gynecomastia. Recent
studies have shown that natural products with aromatase inhibitory activity can also be good options
against secondary recurrence of breast cancer by exhibiting chemopreventive effects. Therefore,
screening for new plant-based aromatase inhibitors may provide novel leads for drug discovery
and development, particularly with increased clinical efficacy and decreased side effects.
Nanomaterial Gas Sensors for Biosensing Applications: A Review
Authors: Kurmendra  
Published: November 2021

Background:
Nanomaterial is one of the most used materials for various gas sensing
applications to detect toxic gases, human breath, and other specific gas sensing. One of the most
important applications of nanomaterial based gas sensors is biosensing applications. In this review
article, the gas sensors for biosensing are discussed on the basis of crystalline structure and different
categories of nanomaterial.

Methods:
In this paper, firstly, rigorous efforts have been made to find out research questions by
going through a structured and systematic survey of available peer reviewed high quality articles in
this field. The papers related to nanomaterial based biosensors are then reviewed qualitatively to
provide substantive findings from the recent developments in this field.

Results:
In this review article, firstly, classifications of nanomaterial gas sensors have been presented
on the basis of the crystalline structure of nanomaterial and different types of nanomaterial
available for biosensing applications. Further, the gas sensors based on nanomaterial for biosensing
applications are collected and reviewed in terms of their performance parameters such as sensing
material used, target gas component, detection ranges (ppm-ppb), response time, operating
temperature and method of detection, etc.
The different nanomaterials possess slightly different sensing and morphological properties due to
their structure; therefore, it can be said that a nanomaterial must be selected carefully for a particular
application. The 1D nanomaterials show the best selectivity and sensitivity for gases available
in low concentration ranges due to their miniaturised structure compared to 2D and 3D nanomaterials.
However, these 2D and 3D nanomaterials also so good sensing properties compared to
bulk semiconductor materials. The polymer and nanocomposites have opened the door for future
research and have great potential for new generation gas sensors for detecting biomolecules.

Conclusion:
These nanomaterials extend great properties towards sensing the application of different
gases for a lower concentration of particular gas particles. Nano polymer and nanocomposites
have great potential to be used as gas sensors for the detection of biomolecules.
Comparison of the Impact of Conventional and Web-Based Pulmonary Rehabilitation on Physical Activity in Patients With Chronic Obstructive Pulmonary Disease: Exploratory Feasibility Study
Authors: Chaplin Emma , Barnes Amy , Newby Chris , Houchen-Wolloff Linzy , Singh Sally J 
Published: November 2021

Background
Pulmonary Rehabilitation (PR) increases exercise capacity, with less clear evidence regarding physical activity (PA). The World Health Organization recommends at least 150-300 minutes of moderate-intensity or 75-150 minutes of vigorous-intensity aerobic PA per week to reduce the risks of chronic disease.

Objective
The objective of this study was to assess the effectiveness of conventional PR versus web-based PR with respect to changes in PA.

Methods
Patients with COPD were randomized to either conventional PR classes (n=51) or a web-based PR program (n=52) for 7 weeks in a feasibility study. Accelerometers (Sensewear) were worn before and after the intervention, and PA was measured as steps per day and mean bouts of moderate activity for ≥2, ≥5, ≥10, and ≥20 minutes. Measures were derived for patients with ≥8 hours of data per day for ≥4 days, using the R package for statistical analysis. Variables were explored to examine their relationships with bouts of activity.

Results
Baseline characteristics did not differ significantly between groups. Complete PA data were available for the groups receiving web-based (n=20) and conventional (n=34) PR interventions. The web-based PR group demonstrated a nonsignificant increase in the number of steps per day, which mainly comprised short bouts of moderate to vigorous intensity PA when compared to the conventional PR group (P=.20). The conventional PR group demonstrated increased 20-minute bouts of PA by 49.1%, although this was not significant (P=.07). At baseline, age (r=–0.21, P=.04), BMI (r=–0.311, P=.004), and FEV1 (forced expiratory volume in 1 second; % predicted; r=–0.248, P=.048) were significantly correlated with 10-minute bouts of PA; however, this was not observed post intervention.

Conclusions
The analysis revealed a nonsignificant difference in the pattern of PA between groups receiving conventional vs web-based PR—the former being associated with an increase in 20-minute bouts, while the latter having demonstrated an increase in the number of steps per day. There appears to be a differing response emerging between the two interventions.

Trial Registration
International Clinical Trials Registry ISRCTN03142263; https://tinyurl.com/y4dmfyrb
Social Media Platforms Listening Study on Atopic Dermatitis: Quantitative and Qualitative Findings
Authors: Voillot Paméla , Riche Brigitte , Portafax Michel , Foulquié Pierre , Gedik Anaïs , Barbarot Sébastien , Misery Laurent , Héas Stéphane , Mebarki Adel , Texier Nathalie , Schück Stéphane 
Published: November 2021

Background
Atopic dermatitis (AD) is a chronic, pruritic, inflammatory disease that occurs most frequently in children but also affects many adults. Social media have become key tools for finding and disseminating medical information.

Objective
The aims of this study were to identify the main themes of discussion, the difficulties encountered by patients with respect to AD, the impact of the pathology on quality of life (QoL; physical, psychological, social, or financial), and to study the perception of patients regarding their treatment.

Methods
A retrospective study was carried out by collecting social media posts in French language written by internet users mentioning their experience with AD, their QoL, and their treatments. Messages related to AD discomfort posted between July 1, 2010, and October 23, 2020, were extracted from French-speaking publicly available online forums. Automatic and manual extractions were implemented to create a general corpus and 2 subcorpuses depending on the level of control of the disease.

Results
A total of 33,115 messages associated with AD were included in the analysis corpus after extraction and cleaning. These messages were posted by 15,857 separate web users, most of them being women younger than 40 years. Tips to manage AD and everyday hygiene/treatments were among the most discussed topics for controlled AD subcorpus, while baby-related topics and therapeutic failure were among the most discussed topics for insufficiently controlled AD subcorpus. QoL was discussed in both subcorpuses with a higher proportion in the controlled AD subcorpus. Treatments and their perception were also discussed by web users.

Conclusions
More than just emotional or peer support, patients with AD turn to online forums to discuss their health. Our findings show the need for an intersection between social media and health care and the importance of developing new approaches such as the Atopic Dermatitis Control Tool, which is a patient-related disease severity assessment tool focused on patients with AD.
Subaltern jugun ianfu dalam cerpen Kapotjes dan Batu yang Terapung karya Faisal Oddang: Tinjauan poskolonial Gayatri Spivak
Authors: Bahardur Iswadi 
Published: November 2021

Eksploitasi seksual dan kekerasan fisik yang dilakukan tentara Jepang terhadap perempuan pribumi di era penjajahan tahun 1942-1945 yang direpresentasikan kembali dalam teks-teks sastra pascakolonial, menjadi satu hal yang menarik untuk dikaji. Relevan dengan latar belakang tersebut, tujuan penelitian ini adalah menganalisis dan mengungkapkan permasalahan perempuan pribumi yang mengalami subaltern karena dipaksa oleh tentara Jepang menjadi jugun ianfu. Sumber data untuk mengungkapkan permasalah tersebut adalah cerpen karya Faisal Oddang berjudul Kapotjes dan Batu yang Terapung. Data dalam penelitian ini adalah satuan kata, frasa, serta kalimat-kalimat dalam bentuk narasi dalam sudut pandang pengarang, maupun dialog antartokoh yang menggambarkan permasalahan subaltern jugun ianfu. Metode penelitian kualitatif dan pendekatan analisis isi digunakan untuk mengungkapkan masalah perempuan pribumi subaltern yang menjadi jugun ianfu dalam cerpen Kapotjes dan batu Yang Terapung dilakukan melalui telaah penokohan jugun ianfu bernama Suriani atau Hana. Telaah terhadap penokohan Suriani meliputi gambaran fisik, psikis, tindakan, kepribadian, dan relasi dominasi superior tokoh lain terhadap Suriani yang tergambar dalam teks dialog dan monolog cerpen. Tahapan analisis isi yang diterapkan adalah metode analisis hermeneutika, sesuai dengan pandangan Krippendoff. Hasil penelitian menunjukkan subalternisasi terhadap jugun ianfu dalam cerpen Kapotjes dan Batu yang Terapung terjadi karena dominasi kekuasaan tentara Jepang yang diwujudkan dalam (1) tindakan pelecehan fisik, (2) perkosaan, (3) eksploitasi dan perdagangan seksual, (4) penggantian identitas, (5) paksaan menghormati lagu kebangsaan Jepang, serta (6) penghilangan hak-hak kebebasan perempuan yang dipaksa menjadi jugun ianfu. Dominasi tersebut berdampak pada kerusakan fisik serta trauma psikis yang bermuara pada upaya perlawanan.
The Representation of Syrian Refugees in Canadian Online News Media: A Focus on the Topos of Burdening
Authors: Mustafa Manar , Pilus Zahariah , Mohammad Lotfie Maskanah 
Published: November 2021

Background: This study focuses on the representation of Syrian refugees in Canadian online news media. It examines 375 articles selected from three of the most visited Canadian news sites, namely the Toronto Star, which favours the Liberal Party, and the Toronto Sun and National Post, which favour the Conservative Party. Analysis: The basis of this research is a topoi analysis, whereby instances of the topos of burdening are identified, examined, and categorized as either positive or negative. Conclusion and implications: A distinction is drawn between the depiction of Syrian refugees in conservative- and liberal-leaning news sources. The findings aim to provide some insight into the possible impact of media representation on both the Syrian refugees and the Canadian public.
Enemy Imaginaries: A Case Study of the Far Right in Canada
Authors: Neville Stephen J. , Langlois Ganaele 
Published: November 2021

Background: Social media and digital technology play a central role in amplifying the potential harms of the far right. Analysis: The concept of enemy imaginaries is developed to map the digital and social media practices of far-right actors and groups in their antagonistic participation with and against a liberal, multicultural, globalist imagined community. Analysis focuses on a dramatic clash at a People’s Party of Canada event in Hamilton, Ontario, during the 2019 federal election. Conclusion and implications: Disparate far-right groups can momentarily crystallize around a particular event to define new nationalist objects that are symbolic of their networked and mediated fight against an imagined enemy.
Political Crowdfunding and Campaigning on GoFundMe
Authors: Elmer Greg , Ward-Kimola Sabrina 
Published: November 2021

Background: What does the Canadian use of GoFundMe tell us about the role of non-party campaigners in contemporary election campaigning? Analysis: Within the context of the 2019 Canadian federal election, this article examines how GoFundMe has been used as a platform for fundraising by fringe and populist political voices online. Conclusion and implications: The crowdfunding platform GoFundMe has been leveraged to meet political goals both within and outside of traditional, party-centred, political fundraising setups. The mobilization of GoFundMe’s crowdfunding tools in the 2019 federal election presented an opportune space for the financialization of political goals reflecting right-wing populist ideas.