bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Snowmaking Conditions Based on Meteorological Reconstruction in the Beijing–Zhangjiakou Mountain Area of North China in 1978–2017
Authors: Chen Jing , Wang Ji , Lin Runsheng , Lu Li 
Published: June 2021

AbstractThe outdoor events of the 2022 Winter Olympics and Paralympics will be held in the mountain areas of Beijing–Zhangjiakou, North China, where there is a complete reliance on artificial snow production owing to the dry and cold weather conditions. To assess how favorable the meteorological conditions are to snowmaking at the mountain venues, we reconstructed the daily wet-bulb temperature by adopting the thin-plate smoothing spline function method, and then we assessed the potential number of snowmaking days at eight weather stations (928–2098 m MSL) from October to the next April (i.e., the ski season) during the period 1978–2017. Results showed that artificial snow production would have been possible on 121 (±14) to 171 (±12) days on average at the stations with the increases of altitude, and the number of days decreased at rates of 4.3–5.1 days decade−1 across four decades of the study period. The cause of the decrease was the warming trend, which affected the number of days in low-altitude sites simultaneously, but the reduction was delayed with increased elevation. At monthly scale, the number of snowmaking days was robust in wintertime but reduced in other months of the ski season, particularly in March in more recent subperiods at high-altitude stations, which was determined by the increase in high values of daily mean wet-bulb temperature. Further improvements in assessing snowmaking conditions require detailed microclimatic studies to reduce the uncertainties caused by meteorological conditions as well as combination with model-based methods to determine potential future changes.
Spatial and temporal trends and variabilities of hailstones in the United States Northern Great Plains and their possible attributions
Authors: Jeong Jong-Hoon , Fan Jiwen , Homeyer Cameron R. 
Published: June 2021

AbstractFollowing on our study of hail for the Southern Great Plains (SGP), we investigated the spatial and temporal hail trends and variabilities for the Northern Great Plains (NGP) and the contributing factors for summers (June–August) focusing on the period of 2004–2016 using two independent hail datasets. Analysis for an extended period (1994–2016) with the hail reports was also conducted to more reliably investigate the contributing factors. Both severe hail (1″ < diameter ≤ 2″) and significant severe hail (SSH; diameter > 2″) were examined and similar results were obtained. The occurrence of hail over the NGP demonstrated a large interannual variability, with a positive slope overall. Spatially, the increase is mainly located in the western part of Nebraska, South Dakota, and North Dakota. We find the three major dynamical factors that most likely contribute to the hail interannual variability in the NGP are the El Niño-Southern Oscillation (ENSO), North Atlantic subtropical high (NASH), and low-level jet (LLJ). With a thermodynamical variable integrated water vapor transport that is strongly controlled by LLJ, the four factors can explain 78% of the interannual variability in the number of SSH reports. Hail occurrences in the La Niña years are higher than the El Niño years since the jet stream is stronger and NASH extends further into the southeastern United States, thereby strengthening the LLJ and in turn water vapor transport. Interestingly, the important factors impacting hail interannual variability over the NGP are quite different from those for the SGP, except for ENSO.
Quantifying the Mechanisms of Atmospheric Circulation Response to Greenhouse Gas Increases in a Forcing-Feedback Framework
Authors: Zhang Pengfei , Chen Gang , Ming Yi 
Published: June 2021

AbstractWhile there is substantial evidence for tropospheric jet shift and Hadley cell expansion in response to greenhouse gas increases, quantitative assessments of individual mechanisms and feedback for atmospheric circulation changes remain lacking. We present a new forcing-feedback analysis on circulation response to increasing CO2 concentration in an aquaplanet atmospheric model. This forcing-feedback framework explicitly identifies a direct zonal wind response by holding the zonal mean zonal wind exerting on the zonal advection of eddies unchanged, in comparison with the additional feedback induced by the direct response in zonal mean zonal wind. It is shown that the zonal advection feedback accounts for nearly half of the changes to the eddy-driven jet shift and Hadley cell expansion, largely contributing to the subtropical precipitation decline, when the CO2 concentration varies over a range of climates. The direct response in temperature displays the well-known tropospheric warming pattern to CO2 increases, but the feedback exhibits negative signals. The direct response in eddies is characterized by a reduction in upward wave propagation and a poleward shift of midlatitude eddy momentum flux (EMF) convergence, likely due to an increase in static stability from moist thermodynamic adjustment. In contrast, the feedback features a dipole pattern in EMF that further shifts and strengthens midlatitude EMF convergence, resulting from the upper-level zonal wind increase seen in the direct response. Interestingly, the direct response produces an increase in eddy kinetic energy (EKE), but the feedback weakens EKE. Thus, the forcing-feedback framework highlights the distinct effect of zonal mean advecting wind from direct thermodynamic effects in atmospheric response to greenhouse gas increases.
Ocean glider flight in the presence of surface waves
Authors: Merckelbach Lucas M. , Carpenter Jeffrey R. 
Published: June 2021

AbstractAutonomous, buoyancy-driven ocean gliders are increasingly used as a platform for the measurement of turbulence microstructure. In the processing of such measurements, there is a sensitive (quartic) dependence of the turbulence dissipation rate, ϵ, on the speed of flow past the sensors, or alternatively, the speed of the glider through the ocean water column. The mechanics of glider flight is therefore examined by extending previous flight models to account for the effects of ocean surface waves. It is found that due to the relatively small buoyancy changes used to drive gliders, the surface wave-induced motion, superimposed onto the steady-state motion, follows to a good approximation the motion of the wave orbitals. Errors expected in measuring ϵ at the ocean near-surface due to wave-induced relative velocities are generally less than 10%. However, pressure perturbations associated with the wave motion can be significant when using the glider-measured pressure signal to infer the glider vertical velocity. This effect of surface waves is only present in the shallow water regime, and can also affect glider depth measurements. It arises from an incomplete cancellation of the wave-induced pressure perturbation with the hydrostatic component due to vertical glider displacements, whereas for deep-water waves this cancellation is complete.
The Early Evening Transition in Southeastern U.S. Tornado Environments
Authors: Brown Matthew C. , Nowotarski Christopher J. , Dean Andrew R. , Smith Bryan T. , Thompson Richard L. , Peters John M. 
Published: June 2021

AbstractThe response of severe local storms to environmental evolution across the early evening transition (EET) remains a forecasting challenge, particularly within the context of the Southeast U.S. storm climatology, which includes the increased presence of low-CAPE environments and tornadic nonsupercell modes. To disentangle these complex environmental interactions, Southeast severe convective reports spanning 2003–18 are temporally binned relative to local sunset. Sounding-derived data corresponding to each report are used to characterize how the near-storm environment evolves across the EET, and whether these changes influence the mode, frequency, and tornadic likelihood of their associated storms. High-shear, high-CAPE (HSHC) environments are contrasted with high-shear, low-CAPE (HSLC) environments to highlight physical processes governing storm maintenance and tornadogenesis in the absence of large instability. Last, statistical analysis is performed to determine which aspects of the near-storm environment most effectively discriminate between tornadic (or significantly tornadic) and nontornadic storms toward constructing new sounding-derived forecast guidance parameters for multiple modal and environmental combinations. Results indicate that HSLC environments evolve differently than HSHC environments, particularly for nonsupercell (e.g., quasi-linear convective system) modes. These low-CAPE environments sustain higher values of low-level shear and storm-relative helicity (SRH) and destabilize postsunset—potentially compensating for minimal buoyancy. Furthermore, the existence of HSLC storm environments presunset increases the likelihood of nonsupercellular tornadoes postsunset. Existing forecast guidance metrics such as the significant tornado parameter (STP) remain the most skillful predictors of HSHC tornadoes. However, HSLC tornado prediction can be improved by considering variables like precipitable water, downdraft CAPE, and effective inflow base.
A Novel Educational Tool to Improve Medical Student Knowledge Acquisition During Surgical Rotations
Authors: Portelli Tremont Jaclyn N. , Kratzke Ian M. , Williford Michael L. , Pascarella Luigi 
Published: June 2021

Background The addition of a novel education tool helps students improve understanding of general surgery topics. However, the effect of the new tool on objective exam performance is unknown. Materials A 10-item card of high-yield general surgery topics was implemented in the third-year surgery clerkship. Students reviewed these topics with general surgery residents. Scores from the National Board of Medical Examiners (NBME) surgery subject exam and Step 2 Clinical Knowledge (CK) board exam were compared among students who completed the Ask-a-Resident Topic card to a control group. Results Students who participated in the curriculum demonstrated significantly better scores on the NBME Surgery exam, t (236) = −2.56, P = .006. There was not a significant effect of the curriculum on Step 2 CK scores, although students who participated in the curriculum (M = 250.7, SD = 13.4) achieved higher scores than the control group (M = 247.8, SD = 14.2). Discussion The novel curriculum may improve objective student performance on standardized surgery exams.
The Effectiveness of Information-Motivation-Behavioral Skills Model on Self-Care Practices in Early Pregnancy to Prevent Gestational Diabetes Mellitus in Iranian Overweight and Obese Women: A Randomized Controlled Trial
Authors: Motahari-Tabari Narges Sadat , Nasiri-Amiri F. , Faramarzi Mahbobeh , Shirvani Marjan Ahmad , Bakhtiari Afsaneh , Omidvar Shabnam 
Published: June 2021

Background Gestational diabetes mellitus (GDM) is one of the most common metabolic dysfunction in pregnancy and as overweight and obesity are of the major risk factors. The aim of this study was to determine the effect of Information-Motivation and Behavioral skills (IMB) model-based counseling on preventing GDM in overweight and obese pregnant women. Methods This randomized controlled trial study was conducted on 137 pregnant women in two groups; education and counseling IMB model-based for four sessions ( n = 70), and antenatal usual care (AUC) ( n = 67). This study was conducted on overweight and obese pregnant women, at the 12 to 16 weeks' gestation and recruited from the Prenatal Clinic of Rohani Hospital in north of Iran. Blood glucose was measured before and 8 weeks after the intervention. Descriptive and inferential statistics including mean, frequency, t-test, chi-square and ANCOVA were used. Results The prevalence of GDM was lower in the intervention group than the control group (10% and 29.9%, respectively, RR = 0.33, CI 95% (0.15– 0.74) p = .004) as well as mean fasting blood glucose (Cohen's d = 0.28, p = .07), and glucose tolerance test at the first and second hour ( d = 0.41 and Cohen's d = 0.73, respectively, p < .01). Conclusions A lifestyle intervention in early pregnancy by IMB counseling in overweight and obese pregnant women can be effective in decrease GDM.
Tumor necrosis factor receptor II and PTPN22 genes polymorphisms and the risk of systemic lupus erythematosus in Egyptian children
Authors: Eid Riham , Hammad Ayman , Abdelsalam Maha , Fathy Aya Ahmed , Abd-El Ghafaar Dena M , Elmarghany Eman B , El-Hanafy Aya A , Mostafa Nora , Niazey Nermeen A , Korkor Mai S , Hamdy Nashwa 
Published: June 2021

Background Many genes have been implicated in the pathogenesis of systemic lupus erythematosus (SLE). Tumor necrosis factor (TNF) is a potent cytokine stimulator acting through 2 cell surface receptors (TNFR I and II). TNFRII gene which controls expression of these receptors has been linked to SLE susceptibility through promoting apoptosis. Also; Protein tyrosine phosphatase non receptor 22 (PTPN22) gene enhances intrinsic phosphatase activity of T lymphocytes leading to their dysregulation and stimulates autoimmune process of lupus and its rs2476601 has been linked to susceptibility to thyroiditis in SLE patients in few studies. Objectives (i) to investigate the correlation between 2 SNPs of TNFR II and PTPN22 genes and SLE susceptibility in a cohort of Egyptian children compared to controls (ii) and to investigate their possible association with different clinical presentations of the disease in children. Subjects and methods Typing of TNFR II rs1061622 and PTPN22 rs2476601 SNPs were done using polymerase chain reaction-restriction fragment length polymorphism for 74 children with SLE and 100 matched healthy controls. Results Children with SLE had more frequent G allele and GG genotype of TNFR II rs1061622 ( p < 0.001) and more T allele and TT genotype of PTPN22 rs2476601 ( p = 0.012 and <0.001, respectively) compared to controls. Only 6 patients (8%) had thyroiditis (hypothyroidism) with T allele and TT genotype of PTPN22 1858 T more prevalent in those patients versus those without thyroiditis ( p ≤ 0.001). Apart from, thyroiditis, no significant association was found between genotypes and alleles frequencies of the 2 studied SNPs and other clinical manifestations of the disease. Conclusion The G allele and GG genotype of TNFR II rs1061622 and T allele and TT genotype of PTPN22 rs2476601 genes polymorphism can be considered as risk factors for the development of SLE. The presence of the T allele of PTPN22 rs2476601 may increase the risk of concomitant thyroiditis in Egyptian children with SLE but further studies are required to confirm this finding as thyroiditis was reported only in few cases in this study.
Factors associated with neuropsychiatric involvement in Latin American patients with systemic lupus erythematosus
Authors: Barile-Fabris Leonor A , Fragoso-Loyo Hilda , Wojdyla Daniel , Quintana Rosana , Pons-Estel Guillermo J , Catoggio Luis J , García Mercedes A , Saurit Verónica , Drenkard Cristina , Bonfa Eloisa , Borba Eduardo F , Sato Emilia , Tavares Brenol Joao C , Cavalcanti Fernando , Da Silva Nilzio A , Lavras Costallat Lilian T , Guibert Toledano Marlene , Massardo Loreto , Neira Oscar , Cardiel Mario H , Amigo Mary Carmen , García De La Torre Ignacio , Silveira Luis H , Acevedo Vásquez Eduardo M , Chacón-Diaz Rosa , Esteva-Spinetti María H , Alarcón Graciela S , Pons-Estel Bernardo A ,   On behalf of GLADEL
Published: June 2021

Introduction Factors related to presentation of neuropsychiatric (NP) SLE manifestations, early in the course of the disease, and during follow up have not been clearly established. Purpose To identify disease and non-disease related factors associated with NP manifestations in early SLE. Methods We included 1193 patients from the GLADEL inception cohort free of NP involvement at cohort entry. We evaluated the association of demographic, clinical and laboratory data with NP involvement during follow-up. Statistical methods Independent factors associated with NP involvement were identified using a multivariable Cox regression model. Results Factors independently associated with NP manifestations were: mestizo ethnicity (HR 1.701, 95% CI 1.282–2.258, p = 0.0002), myalgias/myositis (HR 1.832, 95% CI 1.335–2.515, p = 0.0002), pneumonitis (HR 2.476, 95% CI 1.085–5.648, p = 0.0312), shrinking lung (HR 2.428, 95% CI 1.074–5.493, p = 0.0331) and hemolytic anemia (HR 1.629, 95% CI 1.130–2.347, p = 0.0089). Longer disease duration at cohort entry (13 to 24 months) was associated with a lower risk of developing NP manifestations (HR 0.642, 95% CI 0.441–0.934, p = 0.0206). Conclusions Patients with myalgias/myositis, pneumonitis, shrinking lung and hemolytic anemia are at higher risk of NP involvement, whereas longer disease duration at cohort entry is associated with a lower risk of developing NP involvement.
Exploring the Relationship Between Palatal Cleft Type and Width With the Use of Relieving Incisions in Primary Repair
Authors: Davies Alex , Davies Amy , Wren Yvonne , Deacon Scott , Cobb Alistair R.M. , Chummun Shaheel 
Published: June 2021

Objective: The mainstay of palatal repair in the United Kingdom is the intravelar veloplasty (IVVP). It is not always possible to align the oral mucosa in the midline to achieve tension-free repair. The addition of lateral relieving incisions may aid transposition of the oral mucosa to allow closure. The aim of this study was to explore cleft features that may predispose to a requirement for relieving incisions in order to allow palate closure. Design: We performed a national multiinstitutional retrospective study using data from the UK Cleft Collective cohort study. Patients: The study sample consisted of 474 patients who had undergone IVVP at the time of palatal closure across all 16 of the UK cleft units. Results: We found strong evidence for the requirement for relieving incisions in patients with an increased degree of clefting per the Veau classification ( P < .001), increasing palatal soft-edge width ( P < .001) and moderate evidence of an associated use in patients with Pierre Robin sequence ( P = .015). Insufficient data were available to explore the relationship between intertuberosity distance and the presence of fistula formation with the use of relieving incisions. Conclusions: The results of this study identify cleft features that increase the likelihood for requiring lateral relieving incisions to allow palatal closure. The degree to which the addition of relieving incisions to IVVP affects maxillary growth and speech outcomes is unknown. Further study is required to answer this important question.
Blinatumomab-related pneumatosis intestinalis in a pediatric patient with relapsed acute lymphoblastic leukemia: A case report
Authors: Kim Sung Eun , Lee So Mi , Kim Ji Yoon 
Published: June 2021

Introduction Pneumatosis intestinalis is characterized by air in the subserosal or submucosal layer of the intestine, with the severity ranging from mild and asymptomatic to symptomatic with serious conditions such as intestinal ischemia and perforation requiring surgery. Although several etiologies, including those from conventional chemotherapy agents and molecular target agents, have been suggested, blinatumomab-related pneumatosis intestinalis is quite rare. Case report An 11-year-old girl with history of B-cell ALL presented with bone marrow relapse 3 years after completion of initial chemotherapy. Reinduction chemotherapy and blinatumomab as post-reinduction consolidation were initiated. On day 28 of blinatumomab therapy, pneumatosis intestinalis from the ascending colon to the hepatic flexure was found incidentally on abdominal computed tomography. Management and outcome: After withholding blinatumomab therapy for 1 month, pneumatosis intestinalis improved significantly without abnormal gastrointestinal symptoms. Blinatumomab was resumed and safely completed. The computed tomography performed 4 months later showed complete resolution of pneumatosis intestinalis. The patient has been in good condition for over 1 year to date. Discussion To our knowledge, this is the first case report of pneumatosis intestinalis after blinatumomab therapy in a pediatric patient with relapsed precursor B-cell acute lymphoblastic leukemia. Herein, we highlight the importance of early detection of pneumatosis intestinalis through imaging follow-up during blinatumomab therapy.
Comparison of ultrasound-guided femoral artery cannulation versus palpation technique in neonates undergoing cardiac surgery
Authors: Salık Fikret , Bıçak Mustafa 
Published: June 2021

Objectives: Palpation technique for femoral artery cannulation can be very difficult, especially in neonates. In this study, we evaluated whether ultrasound-guided cannulation of the femoral artery is superior to palpation technique in neonates undergoing cardiac surgery. Methods: Forty neonates undergoing cardiac surgery were prospectively randomized into two groups (Ultrasound group and Palpation group). Access time, number of attempts, number of successful cannulations on first attempt, success rate, number of cannulas used, inadvertent access, and complications were compared between the two groups. Cost analyses of the cannulation were performed in two groups. Results: In the ultrasound group, access time for femoral artery cannulation was shorter (6.4 ± 3.0 and 10.2 ± 4.4, p = 0.003) and the number of attempts (1.4 ± 0.6 and 2.3 ± 0.8, p < 0.001) was lower compared to the palpation group. The number of successful cannulations on first-attempt (15 (75%) and 5 (25%), p = 0.002) and the success rate (95% (19) and 60% (12), p = 0.008) were higher in the ultrasound group. The number of cannulas used in the ultrasound group was less than the palpation group ( p = 0.001). The cost of intervention was higher in the palpation group compared to the ultrasound group ( p = 0.048). Conclusions: The ultrasound-guided cannulation of the femoral artery in neonates is superior to the palpation technique based on the increased of the number of successful first-attempt cannulation and success rate, and the reducing of the access time, number of attempts, number of cannulas used, and cost of cannulation.