bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural and Spectral characterization, Topological study and activity prediction of antiviral (E)-5-(diethylamino)-2-((3,5-dinitrophenylimino)methyl)phenol against SARS-CoV-2 Main Protease
Authors: esme asli 
Published: October 2021

Abstract
The (E)-5-(diethylamino)-2-((3,5-dinitrophenylimino)methyl)phenol was deliberated by Ultraviolet-Visible (UV-Vis) and Fourier Transform Infrared (FT-IR) spectroscopy techniques. Hirshfeld surface analysis was performed to analyze the contribution of intermolecular contacts in crystal structure of the studied Schiff base ligand. The plots of the highest occupied molecular orbital (HOMO), the lowest unoccupied molecular orbital (LUMO), and the electrostatic potential (ESP) were used to research the nucleophilic and electrophilic attack sites for the Schiff base ligand. According to the ESP analysis, the electrophilic reactivity was mainly found in nitro and hydroxy groups attached to phenyl rings, while the nucleophilic attack was more concentrated on hydrogen atoms. Major contributions from molecular orbitals to the electronic transitions computed according to the time-dependent DFT (TD-DFT) method were investigated using chloroform as a solvent. The topological parameters; electron density, Laplacian of electron density, kinetic energy, electron potential energy density, total electron energy density, ellipticity, hydrogen bond energy at the bond critical points have been evaluated. The compound was docked into the severe acute respiratory syndrome coronavirus 2, including a 3-chymotrypsin-like protease receptor's active site with the PDB ID 6LU7. The Schiff base ligand exhibited a good activity against coronavirus main protease receptor with 6LU7 protein as compared with Chloroquine, Favipiravir, and Remdesivir with −4.68 kcal/mol value of the binding energy.
Distinct Influences of Cold Vortex Over Northeast China On Local Extreme Precipitations in Early Summer And Midsummer
Authors: Xue Daokai , Zhang Yaocun , Wang Pinya , Sun Fenghua , Yin Jingnan 
Published: October 2021

Abstract
The station observations and reanalysis dataset are utilized to identify the cold vertex over Northeast China (NECV) in early summer (ES) and midsummer (MS) respectively. In this study, we focus on the characteristics of NECV and their distinct influences on local precipitations in ES and MS. The underpinning mechanisms are further inspected in terms of thermodynamic and dynamic processes. Results suggest that in ES (MS) the NECV is mainly located over Northern China-Southeastern Russia (Mongolia) and significantly correlated to the precipitations over the eastern (mid-western) regions of Northeast China. In the cases of extreme precipitations, NECV displays northward shift and intensification in ES and MS respectively. Meanwhile, the upper-level wind anomalies suggest a northward displacement of polar front jet and a weakened subtropical jet in ES, and an enhanced polar front jet and a southward shift of subtropical jet in MS. The wind anomalies induced by meridional temperature gradients and the Rossby wave activities transported to Northeast China encourage the development of atmospheric circulation vorticity and then promote the variations of NECV. Furthermore, the vorticity and temperature advections are favorable to the enhancement of ascending motion under quasigeostrophic approximation, which is combined with the sufficient water vapor transported from oceanic regions, triggering the regional extreme precipitations. Intriguingly, the pathways of water vapor transport and disturbance energy propagation caused by the diverse external forcings are different in ES and MS, which sheds some fresh light on the insight into the subseasonal variations of NECV and the distinctive contributions to extreme precipitations.
Revealing Fundamentals of Charge Extraction in Photovoltaic Devices Through Potentiostatic Photoluminescence Imaging
Authors: Wagner Lukas , Schygulla Patrick , Herterich Jan , Elshamy Mohamed , Bogachuk Dmitry , Zouhair Salma , Mastroianni Simone , Würfel Uli , Liu Yuhang , Zakeeruddin Shaik , Graetzel Michael , Hinsch Andreas , Glunz Stefan 
Published: October 2021

Abstract
The photocurrent density-voltage (J(V)) curve is the fundamental characteristic to assess opto-electronic devices, in particular solar cells. However, it only yields information on the performance integrated over the entire active device area. Here, a method to determine a spatially resolved photocurrent image by voltage-dependent photoluminescence microscopy is derived from basic principles. The opportunities and limitations of the approach are studied by the investigation of III-V and perovskite solar cells. This approach allows the real-time assessment of the microscopically resolved local J(V) curve, the steady-state Jsc, as well as transient effects. In addition, the measurement contains information on local charge extraction and interfacial recombination. This facilitates the identification of regions of non-ideal charge extraction in the solar cells and enables to link these to the processing conditions. The proposed technique highlights that, combined with potentiostatic measurements, luminescence microscopy turns out to be a powerful tool for the assessment of performance losses and the improvement of solar cells.
Hemolytic Iron Regulation in Traumatic Brain Injury and Alcohol Use
Authors: Agas Agnieszka , Ravula Arun Reddy , Ma Xiaotang , Cheng Yiming , Belfield Kevin D. , Haorah James 
Published: October 2021

Abstract
Hemorrhage is often a major component of traumatic brain injury (TBI). Red blood cells (RBCs) accumulated at the hemorrhagic site undergo hemolysis upon energy depletion. Hemolysis of RBCs is expected to release free iron into the central nervous system (CNS) that must be managed to prevent iron neurotoxicity. Here, we examine the hypothesis that chronic alcohol consumption, as a secondary stressor, may increase iron toxicity in an animal model of TBI by altering the iron management pathways. To our best knowledge, this innovative idea with significant scientific premises has not been examined to date. We found huge accumulation of free irons at the site of hemorrhage with evidence of hemolytic activity. Our observation showed that alcohol use altered the three distinct iron management pathways of transferrin/hemosiderin binding, lipocalin 2/heme oxygenase 1/ferritin system, and microglial phagocytosis. Presence of alcohol prolonged the expression of lipocalin 2 at the site of hemorrhage compared with injury alone, while the combined effects of alcohol and TBI elevated the levels of heme oxygenase 1 earlier than TBI alone. Hippocampus, neocortex, and around vessels near the site of impact appeared to be the prominent brain regions of induction. The presence of alcohol notably increased the levels of ferritin that sustained for up to 7 days. We also provide evidence that microglia also play a role in iron management through RBC phagocytosis. These results reveal the intricacy and plasticity of iron management and highlight the importance of proper iron regulation in the CNS.
Reconceptualization of Eating Addiction and Obesity as Displacement Behavior and a Possible Treatment
Authors: Pretlow Robert A , Glasner Suzette 
Published: October 2021

Abstract
Purpose: Displacement behavior is a bio-behavioral mechanism that allows an animal to deal with situations that cannot readily be faced nor avoided, or that are thwarting. It may explain compulsive overeating (eating addiction). Resembling addiction, displacement behavior is irrepressible behavior that is contextually inappropriate, e.g., sleeping or feeding when threatened by a predator, or binge eating in response to a work altercation. It is thought to be due to rechanneling of overflow brain energy to another drive (e.g., feeding drive) when two drives, e.g., fight or flight, equally oppose each other. Moving the opposing drives out of equilibrium, by resolving the person’s underlying problem/stressful situations, theoretically should mitigate the displacement mechanism and addictive overeating. Methods: We developed a mobile phone intervention targeting addictive overeating, including a displacement mechanism component. A displacement use subgroup (N=37) ages 14-24 with obesity (mean BMI= 38.1) identified life situations they could neither face nor avoid, or that were thwarting them, and developed action plans to address each situation. Feasibility and acceptability were evaluated. Results: Participants found the displacement component to be understandable and user-friendly. The majority (26/37 – 70%) used the core “Dread List” feature to input 90 individual dreaded/problem situations fueling displacement-based overeating, coupled with action plans to address each problem. Conclusion: The displacement mechanism may be a useful basis for treatment of eating addiction and obesity, and may provide individuals with hope that they can curb their addiction without relying on willpower to not overeat. A randomized trial evaluating the displacement intervention is planned.
Impact of the COVID-19 pandemic in Mexican residency programs: Implications and Experiences for the Continuing Professional Development of Residents
Authors: Domínguez-Varela Irving Armando , Esparza-Sandoval Alejandra Celina , Palomares-Ramos Irving Augusto , García-Madrigal María José , Valdez-García Jorge Eugenio 
Published: October 2021

Abstract
Introduction: The COVID-19 pandemic has forever changed the way to evaluate and teach residents, fellows, and medical students by means of new demanding learning modalities and alternatives to leverage from this new lifestyle without affecting our training as medical specialists. As of January, 24 2021, the number of confirmed cases and deaths by COVID-19 both in Mexico and around the world have been continuously growing (1,752,347 and 149,084 vs. 99,596,451 and 2,135,068, respectively). Mexico registers the world’s highest number of deaths from coronavirus among health workers, with 1,320 deaths confirmed. Methods: Four residents of different specialties analyzed and described how the pandemic affected and benefited the ongoing residency program and exposed some recommendations for each specialty. Results/Discussion: In Mexico, residents from all specialties are rotating in the COVID-designated area working as general practitioners exclusively for hospitalized COVID-19 patients. Our residency program has had to put a stop to routine activities such as academic sessions, specialty consultations, practices, and surgeries. Conclusion: Nothing will replace the insights of the training from real surgical practices, but new and forgotten resources can be used to help assess surgical proficiency.
Service Migration in a Distributed Virtualization System
Authors: Pessolani Pablo , Re Luis Santiago , Fleitas Tomás Andrés 
Published: October 2021

Cloud applications are usually formed by different components (microservices) that may be located in different virtual and/or physical computers. To achieve the desired level of performance, availability, scalability, and robustness in this kind of system developers are forced to maintain and configure complex sets of infrastructure, platforms and frameworks which are expensive to implement, operate and manage.
Another approach would be to use a Distributed Virtualization System (DVS) that provides a transparent mechanism that each component could use to communicate with others, regardless of their location and thus, avoiding the potential problems and complexity added by their distributed execution. This communication mechanism already has useful features for developing commercial-class distributed applications, such as replication support (active and passive) and process migration.
In general, process migration is used when a node in the cluster is overloaded, or it has been scheduled to be disconnected in order to save energy or to do maintenance tasks in it. When this occurs, it is very important that any application using a service running in that node does not end up being affected by the migration.
This article describes the mechanisms used for the migration of server processes between nodes of a DVS cluster in a transparent way for client and server processes, doing special focus on how to solve the problem of keeping client/server communications active even when the server process location has changed.
Unrevealing the impact of pulsed electric fields (PEF) on cucumber seed vigour and surface disinfection
Authors: Atmaca Bahar , Akdemir Evrendilek Gulsun , Bulut Nurullah , Uzuner Sibel 
Published: October 2021

Abstract
Chemicals used for seed treatments help to increase the agricultural production by preventing pests and pathogens but also cause environmental and health problems. Thus, environmentally-friendly technologies need to be developed for a seed treatment that inactivates surface microflora and improves seed vigor. One such pulsed electric field (PEF) treatment applied to cucumber seeds in the range of 1.07-17.28 Joule (J) significantly enhanced a mean germination rate (MGR) by up to 9%, a normal seedling rate by 25.73%, and a resistance to 100 and 200 mM salt stresses by 96% and 91.67%, respectively, with a stronger and faster growth of roots and seedlings. PEF treatment provided 3.34 and 3.22 log-reductions in the surface microflora of total mold and yeast and total aerobic mesophilic bacteria, respectively. The electrical conductivity (EC) values of the control samples increased over time, from 4 to 24 h. Those of the PEF-treated samples after 4, 12, and 24th hours were also more affected by the measurement time not by the PEF treatment.
The joint optimization of 18 responses based on the best-fit Gaussian process model pointed to 19.78 s and 17.28 J as the optimal settings. The PEF treatment appeared to improve seed germination ability and stress resistance with the adequate inactivation of surface microflora.
The four weeks before lockdown during the COVID-19 pandemic in Germany: a weekly serial cross-sectional survey on risk perceptions, knowledge, public trust and behaviour, 3 to 25 March 2020
Authors: Betsch Cornelia , Korn Lars , Burgard Tanja , Gaissmaier Wolfgang , Felgendreff Lisa , Eitze Sarah , Sprengholz Philipp , Böhm Robert , Stollorz Volker , Ramharter Michael , Promies Nikolai , De Bock Freia , Schmid Philipp , Renner Britta , Wieler Lothar H , Bosnjak Michael 
Published: October 2021

Background
During the COVID-19 pandemic, public perceptions and behaviours have had to adapt rapidly to new risk scenarios and radical behavioural restrictions.

Aim
To identify major drivers of acceptance of protective behaviours during the 4-week transition from virtually no COVID-19 cases to the nationwide lockdown in Germany (3–25 March 2020).

Methods
A serial cross-sectional online survey was administered weekly to ca 1,000 unique individuals for four data collection rounds in March 2020 using non-probability quota samples, representative of the German adult population between 18 and 74 years in terms of age × sex and federal state (n = 3,910). Acceptance of restrictions was regressed on sociodemographic variables, time and psychological variables, e.g. trust, risk perceptions, self-efficacy. Extraction of homogenous clusters was based on knowledge and behaviour.

Results
Acceptance of restrictive policies increased with participants’ age and employment in the healthcare sector; cognitive and particularly affective risk perceptions were further significant predictors. Acceptance increased over time, as trust in institutions became more relevant and trust in media became less relevant. The cluster analysis further indicated that having a higher education increased the gap between knowledge and behaviour. Trust in institutions was related to conversion of knowledge into action.

Conclusion
Identifying relevant principles that increase acceptance will remain crucial to the development of strategies that help adjust behaviour to control the pandemic, possibly for years to come. Based on our findings, we provide operational recommendations for health authorities regarding data collection, health communication and outreach.
LEMON AROMATHERAPY AS AN ALTERNATIVE TO REDUCE THE INTENSITY OF CHEMOTHERAPY-RELATED NAUSEA AND VOMITING EXPERIENCED BY THE BREAST CANCER PATIENTS
Authors: Hastuti Puji , Nurhayati Yuli , Ernawati Dwi , Yuliastuti Christina , Widyastuti Merina 
Published: October 2021

ABSTRACT
Introduction : The mechanism of breast cancer is the cells growing and breeding become appear abnormal tissue of breast. One of the common treatments for it is chemotherapy using cytotoxic drugs. However, chemotherapy may cause nausea and vomiting as its side effects. Lemon aromatherapy is a complementary therapy in patients with breast cancer who experience nausea or vomiting. The study’s purpose was to know the effect of lemon aromatherapy on the intensity of nausea and vomiting experienced by the breast cancer patients as an effect of chemoterapy in the Chemo Center Room of RSAL Dr. Ramelan Surabaya. Material and Methods : The study was the pre-experimental design with pre-post test without control group. There are two variables, lemon aromatherapy is independent, and the intensity of nausea and vomiting is dependent. The sampling technique was nonprobability purposive sampling, with 34 breast cancer patients taken as the sample. A questionnaire was the instrument for collecting the data. The Data collected were analyzed using the Wilcoxon Test (α = 0,05). Results : The study’s result indicated that the lemon aromatherapy was effectively to decrease of the intensity of nausea and vomiting exeperienced by the respondents, with the value of Wilcoxon test p < 0.001. Conclusion : Lemon aromatherapy stimulates the raphe nucleus to produce serotonin. Which function to generate a sense of comfort and calm. For that reason, it can be used as an alternative for taking care of nausea and vomiting experienced by patients with breast cancer as the side effect of chemotherapy.
Keywords: Lemon Aromatherapy, Nausea, Vomiting, Chemotherapy
Teller Service Satisfaction Level Analysis at BNI Undaan Surabaya Branch
Authors: Mahmud Ahmad Ali , Damayanti Elok 
Published: October 2021

This study aims to find out the analysis of the level of satisfaction of teller services at BNI Undaan Surabaya Branch by using the research dimension consisting of tangible (physical evidence), reliability (reliability), responsiveness (responsiveness), assurance (guarantee) and empathy (empathy). This research is a research that uses the approach qualitative, the technique used in this research is the method of questionnaires and data collection techniques through google form. Then using the gap analysis method and managed to find the gap score is - 0.48 with an average score of -0.096. The research subjects used were customers at BNI Undaan Surabaya Branch which amounted to 50 people. The results showed from 50 respondents known analysis of the quality of teller services to customers at BNI Undaan Surabaya Branch with a Very Dissatisfied attitude of 0%, Dissatisfied 0%, Dissatisfied 0%, Satisfied 9.6% and Very Satisfied 90.4%. Based on the results of the research can be interpreted the quality of service provided by the teller at BNI Undaan Surabaya Branch is Very Satisfied.
Pseudo Weakly Closed Submodules and Related Concepts
Authors: Mohammadali Haibat K. , Dahash Mohammad E. 
Published: October 2021

Let be a commutative ring with identity, and be a unitary left -module. In this paper we introduce the concept pseudo weakly closed submodule as a generalization of -closed submodules, where a submodule of an -module is called a pseudo weakly closed submodule, if for all , there exists a -closed submodule of with is a submodule of such that . Several basic properties, examples and results of pseudo weakly closed submodules are given. Furthermore the behavior of pseudo weakly closed submodules in class of multiplication modules are studied. On the other hand modules with chain conditions on pseudo weakly closed submodules are established. Also, the relationships of pseudo weakly closed submodules with other classes of modules are discussed.
Assessment of Long Distance Chasing Photometer (NAG-ADF-300-2) by Estimating the Drug Atenolol with Povidone Iodine Via CFIA
Authors: Mezaal Elham N. , Turkey Nagam S. 
Published: October 2021

Atenolol was used with povidone iodine to prove the efficiency, reliability and repeatability of the long distance chasing photometer (NAG-ADF-300-2) using continuous flow injection analysis. The method is based on reaction between atenolol and povidone iodine in an aqueous medium. Optimum parameters was studied to increase the sensitivity development of method. Calibration graph was linear in the range of 2-19 mmol/L for cell A and 5-19 mmol/L for cell B. Limit of detection 146.4848 ng/55 µL and 2.6600 µg/200 µL respectively to cell A and cell B. Correlation coefficient (r) 0.9957 for cell A and 0.9974 for cell. Relative standard deviation (RSD %) was lower than 1%, (n=8) for the determination of atenolol at concentration (5, 9 and 17) mmol/L for cell A and (5, 13 and 17) mmol/L for cell B respectively. The results were compared with classical method UV-spectrophotometric at λ max=270 nm by using method standard addition via t-test, at 95% confidence level. The comparison of data explain that long distance chasing photometer (NAG-ADF-300-2) is the choice with excellent extended detection and wide application.
تقييم كفاءة الخدمات التعليمية و الصحية في مدينة قلعة سكر
Authors: عزيز عبد الرزاق موسى رهام 
Published: October 2021

تناول هذا البحث تقييم كفاءة الخدمات التعليمية والصحية في مدينة قلعة سكر وهي مركز قضاء قلعة سكر ووحدة إدارية تقع ضمن محافظة ذي قار وتقع في الجزء الشمالي من مدينة الناصرية, الواقعة ما بين دائرتي عرض (32, 51⁻, 31°) شمالاً وخط طول (38،4⁻، 46°) شرقاً وبمساحة تبلغ (480) هكتار تنتظم في (9) أحياء سكنية وبحجم سكاني بلغ سنة 2020 (56203) نسمة . استخدمت الباحثة تقنية نظم المعلومات (GIS )map v.10.1 في توقيع المؤسسات التعليمية والصحية .
اعتمدت الدراسة في جانب كبير منها على العمل الميداني وصُممتْ استمارة استبانة عدد (1) ووزعت منها (150) استمارة ، فضلاً عن الجهد المكتبي وقد شمل المسح الميداني المؤسسات المرتبطة بتلك الخدمات , وتحديد كفاءة الخدمات اعتماداً على عدد من المعايير التخطيطية المحلية وكذلك معياري درجة الرضا السكان وسهولة الوصول. وقد أظهرت الدراسة بأن هناك تباين في توزيع الخدمات التعليمية والصحية, اذ اتضح بأن هناك خلل في كفاءة التوزيع المكاني للخدمات التعليمية والصحية في مدينة قلعة سكر كما أن هناك نقصاً واضحاُ في مقدار الخدمات المقدمة لهذه الأحياء.
تضمنت الدراسة ثلاث مباحث, اذ تناول المبحث الأول المفاهيم النظرية أما المبحث الثاني تضمن كفاءة الخدمات التعليمية والمعيار التخطيطية لدراسة كفاءة تلك الخدمات وجاء المبحث الثالث كفاءة الخدمات الصحية والمعايير التخطيطية المستخدمة لمعرفة مدى كفاءة هذه الخدمات وخرجت الباحثة بعدد من التوصيات على أمل أن تأخذ بها الدوائر المعنية وصولاً إلى تحقيق الأهداف المرجوة .