bluuebunny/crossref_metadata_2025_split huggingface dataset:
Green technology transfer in a developing country: mainstream practitioner views
Authors: Nguyen Hieu Thanh , Hoang Thinh Gia , Nguyen Loan Quynh Thi , Le Hoa Phan , Mai Hoanh Xuan Vu 
Published: February 2021

PurposeThis paper aims to explore green technology (GT) transfer through the perceptions of both business managers and technology specialists, who have been identified as the foremost practitioners of this practice.Design/methodology/approachA total of 22 semi-structured interviews were conducted with business leaders and technology scientists. The interviewees were asked to share their views on the motivations for importing GT; their familiarity with, knowledge of and understanding of GT transfer and the current GT performance in their organization; the key strengths of GT transfer and its limitations; the barriers to the use of GT; and their usefulness. The theoretical framework of actors’ resistance to institutional demands of Oliver (1991) is used as a theoretical lens to investigate the perceptions of the interviewees.FindingsThis study suggests that despite some benefits of the adoption of GT, such as increasing competitive advantage and improving green operations, there are huge concerns over the use and importation of GT. More specifically, almost all the technicians were concerned about the technical risks resulting from the lack of operational tests, the old technologies and the lack of knowledge transfer. Meanwhile, the paucity of specific regulations, guidance and environmental standards has been reported by business managers as one of the primary constraints for this movement.Research limitations/implicationsThis research contributes to the emerging literature on GT transfers in the developing world. It proves that the lack of communication and the scarcity of a true champion for GT efforts have reduced the efficiency of GT transfer.Practical implicationsBy shedding light on the intricate nature of the relationships arising from GT adoption in organizations, this paper aims to support business leaders and standard setters in making a decision regarding the implementation and promotion of GT transfer, especially in the context of developing countries.Originality/valueTo the best of the authors’ knowledge, this is one of the first studies to explore eco-friendly technology transfers in a developing country from the micro-level perspective of both business and technology practitioners of GT-recipient organizations.
Two different approaches of microbial community structure characterization in riverine epilithic biofilms under multiple stressors conditions: Developing molecular indicators
Authors: Pin Lorenzo , Eiler Alexander , Fazi Stefano , Friberg Nikolai 
Published: February 2021

AbstractMicrobial communities are major players in the biogeochemical processes and ecosystem functioning of river networks. Despite their importance in the ecosystem, biomonitoring tools relying on prokaryotes are still lacking. Only a few studies have employed both metabarcoding and quantitative techniques such as catalysed reported deposition fluorescence in situ hybridization (CARD‐FISH) to analyse prokaryotic communities of epilithic biofilms in river ecosystems. We intended to investigate the efficacy of both techniques in detecting changes in microbial community structure associated with environmental drivers. We report a significant correlation between the prokaryotic community composition and pH in rivers from two different geographical areas in Norway. Both CARD‐FISH and metabarcoding data were following the pattern of the environmental variables, but the main feature distinguishing the community composition was the regional difference itself. Beta‐dispersion analyses on both CARD‐FISH abundance and metabarcoding data revealed higher accuracy of metabarcoding to differentiate regions and river systems. The CARD‐FISH results showed high variability, even for samples within the same river, probably due to some unmeasured microscale ecological variability which we could not resolve. We also present a statistical method, which uses variation coefficient and overall prevalence of taxonomic groups, to detect possible biological indicators among prokaryotes using metabarcoding data. The development of new prokaryotic bioindicators would benefit from both techniques used in this study, but metabarcoding seems to be faster and more reliable than CARD‐FISH for large scale bio‐assessment.
The use of minimal invasive extracorporeal circulation for rewarming after accidental hypothermia and circulatory arrest
Authors: Friess Jan O. , Gisler Fabian , Kadner Alexander , Jenni Hansjoerg , Eberle Balthasar , Erdoes Gabor 
Published: February 2021

BackgroundExtracorporeal cardiopulmonary resuscitation has become a recommended treatment option for patients with severe hypothermia with cardiac arrest. Minimal invasive extracorporeal circulation (MiECC) may offer advantages over the current standard extracorporeal membrane oxygenation (ECMO).MethodsRetrospective cohort analysis of hospital database for patients with accidental hypothermia and extracorporeal rewarming with MiECC admitted between 2010 and 2019.ResultsOverall, six of 17 patients survived to hospital discharge. Eleven patients suffered accidental hypothermia in an alpine and six in an urban setting. Sixteen patients arrived at the hospital under ongoing cardiopulmonary resuscitation (CPR). CPR time was 90 minutes (0‐150). Four patients survived from an alpine setting and two from an urban setting with CPR duration of 90 minutes (0‐150) and 85 minutes (25‐100), respectively. Asphyctic patients tended to have lower survival (one of seven patients). Two patients of six with major trauma survived.ConclusionMiECC for extracorporeal rewarming from severe accidental hypothermia is a feasible alternative to ECMO, with comparable survival rates.
Prevalence of attention‐deficit/hyperactivity disorder in people with mood disorders: A systematic review and meta‐analysis
Authors: Sandstrom Andrea , Perroud Nader , Alda Martin , Uher Rudolf , Pavlova Barbara 
Published: February 2021

AbstractObjectiveAttention‐deficit/hyperactivity disorder (ADHD) in mood disorders is associated with unfavorable outcomes, including more frequent mood episodes, and increased risk of suicide. The reported prevalence of ADHD in individuals with mood disorders varies widely.MethodsWe searched PsycInfo and PubMed for articles published before September 21st, 2020, using search terms for ADHD and mood disorders. We included original data on the prevalence of ADHD in individuals with bipolar disorder (BD) or major depressive disorder (MDD). We estimated the prevalence of ADHD, by developmental period and disorder using random‐effects meta‐analyses. We also compared the rate of ADHD in people with MDD and BD, and with and without mood disorders.ResultsBased on 92 studies including 17089 individuals, prevalence of ADHD in BD is 73% (95% CI 66–79) in childhood, 43% (95% CI 35–50) in adolescence, and 17% (95% CI 14–20) in adulthood. Data from 52 studies with 16897 individuals indicated that prevalence of ADHD in MDD is 28% (95% CI 19–39) in childhood, 17% (95% CI 12–24) in adolescence, and 7% (95% CI 4–11) in adulthood. ADHD was three times more common in people with mood disorders compared to those without and 1.7 times more common in BD compared to MDD.ConclusionPeople with mood disorders are at a significant risk for ADHD. ADHD should be assessed and treated in individuals with BD and MDD. Comprehensive assessment strategies are needed to address challenges of diagnosing ADHD alongside mood disorders.
Dentists’ preferences in implant maintenance and hygiene instruction
Authors: Cheung MC , Hopcraft MS , Darby IB 
Published: February 2021

AbstractBackgroundThis study investigated the preferences of dentists in Australia in providing professional implant maintenance and implant‐specific oral hygiene instructions (OHI).MethodsGeneral dentists were surveyed online about their preferences in peri‐implant diagnostics, maintenance provision, armamentarium used, and implant OHI techniques and frequency.ResultsMost of the 303 respondents (96%) provided maintenance services; 87.6% reviewed implants regularly while 10.7% only performed diagnostics after detecting clinical signs/symptoms. Supragingival prosthesis cleaning was performed by 77.9% of respondents, 35.0% performed subgingival debridement, 41.9% treated peri‐implant mucositis and 18.2% treated peri‐implantitis. About 15% did not treat nor refer peri‐implant disease, including significantly more non‐implant providers and dentists without implant training. Maintenance armamentarium commonly included floss (76.3%), prophylaxis (73.9%), plastic curettes (43.3%) and stainless‐steel ultrasonics (38.0%). Brushing (86.5%), flossing (73.9%) and interdental brush use (68.3%) were most commonly recommended. Implant OHI was repeated routinely by 57.4% of dentists who provided it. Dentists with greater implant training and experience were more likely to perform reviews and complex maintenance procedures.ConclusionsPeri‐implant diagnostics performed, treatments provided and armamentarium varied among dentists. Implant providers and those with higher levels of training had more preventative approaches to implant OHI. Possible shortcomings in disease management and OHI reinforcement were identified.
Enhanced angiogenesis in the 3D dynamic responsive implant for inguinal hernia repair ProFlor
Authors: Amato Giuseppe , Puleio Roberto , Rodolico Vito , Agrusa Antonino , Calò Pietro Giorgio , Di Buono Giuseppe , Romano Giorgio , Goetze Thorsten 
Published: February 2021

AbstractBiologic response to hernia prostheses represents a continuous source of debate. Conventional hernia meshes, in their typical static, passive configuration have been used for decades to reinforce the herniated abdominal wall. These flat implants, mainly fixated with sutures or tacks, induce poor quality fibrotic ingrowth that shrinks the mesh. In groin hernia repair, flat meshes are applied in the delicate inguinal surrounding where uncontrolled development of a scar plate can impair movement and may incorporate the sensitive nerves crossing this area. Complications deriving from mesh fixation and nerve entrapment are frequent and unpleasant for patients. To remedy these problems, a multilamellar shaped 3D device with a dynamic responsive behavior has recently been developed to repair inguinal hernia. Its inherent dynamic compliance during inguinal movements has shown to induce enhanced biological response with ingrowth of newly formed connective tissue, muscle fibers, and nerves. The function of these highly specialized tissue structures is supported by the contextual development of newly formed arteries and veins. The scope of the study was to assess quantity and quality of vessels, which had ingrown in the 3D hernia device in the short‐term, medium‐term, and long‐term post‐implantation, in biopsy specimens gathered from inguinal hernia patients operated with the 3D device. Starting from an early stage, widespread angiogenesis was evident within the 3D structure. Arteries and veins increased in quantity showing progressive development until full maturation of all specific vascular components throughout the mid‐term, to long‐term, post‐implantation. High quality biologic ingrowth in hernia prosthetics needs an adequate vascular support. The broad network of mature arteries and veins evidenced herewith seems to confirm the enhanced biological features of the dynamic responsive 3D device whose features resemble a regenerative scaffold, an ideal feature for the treatment of the degenerative source of inguinal hernia disease.
Role of implantable cardioverter‐defibrillator in patients awaiting heart transplant in the continuous‐flow left ventricular assist device era
Authors: Trivedi Jaimin R. , Slaughter Mark S. , Pan Queeny , Vijaykrishnan Raj , Gopinathannair Rakesh 
Published: February 2021

AbstractImplantable cardioverter‐defibrillators (ICDs) have been shown to have survival advantage in advanced heart failure patients. Few studies have evaluated the role of ICDs in patients supported with continuous‐flow left ventricular assist devices (CFVADs). We aimed to evaluate the impact of ICD and CFVAD on heart transplant (HTx) waiting list survival. We queried the United Network for Organ Sharing (UNOS) thoracic transplant database between years 2007 and 2016 for patients aged ≥ 18 years listed for HTx. Patients receiving devices other than CFVAD were excluded. Patients were divided into groups—with and without CFVAD and further subdivided into groups—with and without ICD use. Kaplan‐Meier curves were used to evaluate the survival outcomes. There were 34 860 patients listed for HTx during study period of which 11 481 (32%) had a CFVAD and 26 139 (75%) had an ICD. Within CFVAD group, patients with ICD were older, more likely male, with higher creatinine and listed as UNOS status 1A. In the No‐CFVAD group, 1‐year waitlist survival was significantly better with ICD use (81% vs. 73%, P < .0001); however, in CFVAD patients, 1‐year survival with ICD use was comparable to No‐ICD use (95% vs. 94%, P = .1). Use of ICD is associated with significantly better heart transplant waitlist survival in patients not supported by CFVAD. In patients supported with CFVAD, the ICD does not offer additional survival benefit.
Extracorporeal circulation during on‐pump cardiac surgery: An evaluation of the energy equivalent pressure index based on waveforms decomposition in harmonics
Authors: Drochon Agnès , Fouquet Olivier , Baufreton Christophe 
Published: February 2021

AbstractThe use of pulsatile perfusion instead of nonpulsatile perfusion during cardiopulmonary bypass continues to be a source of debate. The disagreements among the conclusions of the published studies may be due to different factors: differences in the type of patients included in the studies, differences in the protocol of the studies, and difficulty to quantify the pulsatility of the flow. In the present paper, we propose a quantitative evaluation of Shepard's energy equivalent pressure index, based on the harmonic decomposition of the physiological aortic pressure and flow rate signal. It is thus demonstrated that the surplus energy provided by pulsatile flow remains moderate (of order 10 mm Hg), but that it can be improved by changing the relative shapes of the pressure and flow waves.
Bayesian spatial homogeneity pursuit for survival data with an application to the SEER respiratory cancer data
Authors: Geng Lijiang , Hu Guanyu 
Published: February 2021

AbstractIn this work, we propose a new Bayesian spatial homogeneity pursuit method for survival data under the proportional hazards model to detect spatially clustered patterns in baseline hazard and regression coefficients. Specially, regression coefficients and baseline hazard are assumed to have spatial homogeneity pattern over space. To capture such homogeneity, we develop a geographically weighted Chinese restaurant process prior to simultaneously estimating coefficients and baseline hazards and their uncertainty measures. An efficient Markov chain Monte Carlo (MCMC) algorithm is designed for our proposed methods. Performance is evaluated using simulated data, and further applied to a real data analysis of respiratory cancer in the state of Louisiana.
The role of Popeye domain‐containing protein 1 (POPDC1) in the progression of the malignant phenotype
Authors: Tucker Steven J. , Zorn Alina J. 
Published: February 2021

The Popeye domain‐containing protein 1 (POPDC1), a tight junction‐associated transmembrane protein with a unique binding site for cAMP, has been shown to act as a tumour suppressor in cancer cells. Through interaction with many downstream effectors and signalling pathways, POPDC1 promotes cell adhesion and inhibits uncontrolled cell proliferation, epithelial‐to‐mesenchymal transition and metastasis. However, POPDC1 expression is down‐regulated in many types of cancer, thereby reducing its tumour‐suppressive actions. This review discusses the role of POPDC1 in the progression of the malignant phenotype and highlights the broad range of benefits POPDC1 stabilisation may achieve therapeutically. Cancer stem cells (CSCs) are a key hallmark of malignancies and commonly promote treatment resistance. This article provides a comprehensive overview of CSC signalling mechanisms, many of which have been shown to be regulated by POPDC1 in other cell types, thus suggesting an additional therapeutic benefit for POPDC1‐stabilising anti‐cancer drugs.LINKED ARTICLESThis article is part of a themed issue on New avenues in cancer prevention and treatment (BJP 75th Anniversary). To view the other articles in this section visithttp://onlinelibrary.wiley.com/doi/10.1111/bph.v179.12/issuetoc
Droplet and bone dust contamination from high‐speed drilling during mastoidectomy
Authors: Markey Anne L. , Leong Samuel C. , Vaughan Casey 
Published: February 2021

AbstractObjectivesThe aim of this study was to examine contamination from otolaryngologic procedures involving high‐speed drilling, specifically mastoid surgery, and to assess the adequacy of PPE in such procedures.Design and SettingMastoid surgery was simulated in a dry laboratory using a plastic temporal bone, microscope and handheld drill with irrigation and suction. Comparisons of distance of droplet and bone dust contamination and surgeon contamination were made under differing conditions. Irrigation speed, use of microscope and drill burr size and type were compared.Main Outcome MeasuresMeasurement of the distance of field contamination while performing simulated mastoidectomy and location of surgeon contamination.ResultsThere was a greater distance field contamination and surgeon contamination without the use of the microscope. Contamination was reduced by using a smaller drill burr and by using a diamond burr when compared to a cutting burr. The use of goggles and a face mask provided good protection for the surgeon. However, the microscope alone may provide sufficient protection to negate the need for goggles.ConclusionsWhile the risks of performing mastoid surgery during the coronavirus pandemic cannot be completely removed, they can be mitigated. Such factors include using the microscope for all drilling, using smaller size drill burrs and creating a safe zone around the operating table.
Noninvasive vagus nerve stimulation to reduce ileus after major colorectal surgery: early development study
Authors: Chapman Stephen J. , Helliwell Jack A. , Naylor Maureen , Tassinari Cerys , Corrigan Neil , Jayne David G. 
Published: February 2021

AbstractAimVagus nerve stimulation has emerged as a plausible intervention to reduce ileus after surgery. An early development study was undertaken with the aim of exploring the feasibility of self‐administered, noninvasive vagus nerve stimulation (nVNS) after major colorectal surgery.MethodA parallel‐group, randomized controlled trial was undertaken between 1 January 2018 and 31 August 2019. Forty patients undergoing colorectal surgery for malignancy were allocated equally to Sham and Active stimulation groups. Electrical vagus nerve stimulation was self‐administered bilaterally over the cervical surface landmarks for 5 days before and after surgery. Outcomes of interest were postoperative complications and adverse events measured using the Clavien–Dindo scale, treatment compliance, device usability according to the Systems Usability Scale (SUS) and clinical measures of bowel recovery.ResultsForty patients were randomized and one withdrew, leaving 39 for analysis. Postoperative complications occurred in 9/19 (47.4%) participants receiving Sham and 11/20 (55.0%) receiving Active stimulation and were mostly minor. Compliance with treatment before surgery was 4.7 ± 0.9 days out of 5 days in the Sham group and 4.7 ± 1.1 in the Active group. Compliance with treatment after surgery was 4.1 ± 1.1 and 4.4 ± 1.5, respectively. Participants considered the intervention to be ‘acceptable’ according to the SUS. The most prominent differences in bowel recovery were days to first flatus (2.35 ± 1.32 vs 1.65 ± 0.88) and tolerance of solid diet (2.18 ± 2.21 vs 1.75 ± 0.91) for Sham and Active groups, respectively.ConclusionThis study supports the safety, treatment compliance and usability of self‐administered nVNS in patients undergoing major colorectal surgery.
Growth and convergence in Eastern Partnership and Central Asian countries since the dissolution of the USSR—embarking on different development paths?
Authors: Incaltarau Cristian , Sharipov Ilkhom , Pascariu Gabriela Carmen , Moga Teodor Lucian 
Published: February 2021

AbstractBackgroundSince the dissolution of the USSR, the former Soviet countries not included in the enlargement of the European Union (EU) have experienced divergent development. While the so‐called Eastern Partnership (EaP) countries established closer ties with the EU, the Central Asian (CA) states mostly gravitated towards Russia and China. Thus, despite belonging to a similar economic and political system, the two groups of countries pursued transition to a market‐oriented economy and fostering development with varying results, creating a neat contrast to facilitate the study of patterns of growth and disparity.PurposeBased on an analysis covering more than two decades, the article explores the growth paths of the EaP and CA countries. Given their bumpy economic performances, the article aims, first, to show how these affected economic disparities among them. Second, it aims to identify the factors which most influenced different development trajectories.Approach and methodsThrough analysis of panel data, the article seeks to explain long‐term economic growth (1992–2015) in terms of endowments of production factors, macroeconomic stabilization and transition reforms, external conditions and institutional development. Sources of growth are identified to reveal how they affected income per capita and shaped convergence in the two groups of countries.FindingsThe EaP and CA countries show different growth patterns since the end of communism. While the EaP economies shrank more during the 1990s compared to the CA group, they bounced back faster during the 2000s. The EaP economies, being more closely connected to the EU, were more affected by the Great Recession of 2007–2009 than those of the CA. Overall, economic disparities between these sets of countries have slightly increased. Physical capital, foreign direct investment, natural resources, openness to trade and the transition reforms significantly explain economic growth, with stronger effects in the EaP compared to CA countries, which suggests the EU’s neighbourhood instruments have been effective in promoting growth.Policy implicationsOur findings suggest that stepping up reforms, preserving macroeconomic stability, enhancing openness to trade and accumulating factors of production spurred growth in both EaP and CA countries. Pursuing closer ties with the EU economies fostered growth by strengthening investment, foreign trade, structural and market reforms, and by better use of natural resources.Given the large variations seen between countries in both groups, more detailed country diagnoses are needed to tailor interventions according to the specifics of each country.