bluuebunny/crossref_metadata_2025_split huggingface dataset:
Resistance to Tubulointerstitial Injury in a Mouse Remnant Kidney Model
Authors: Tanaka Shohei , Wakui Hiromichi , Azushima Kengo , Tsukamoto Shunichiro , Yamaji Takahiro , Urate Shingo , Suzuki Toru , Abe Eriko , Taguchi Shinya , Yamada Takayuki , Kobayashi Ryu , Kanaoka Tomohiko , Kinguchi Sho , Yamashita Akio , Ishigami Tomoaki , Tamura Kouichi 
Published: March 2021

Abstract
Numerous animal models of CKD have been developed, but mice are relatively resistant to kidney injury. The remnant kidney model mimics progressive renal failure, and widely used in CKD research. The present study was performed to evaluate the effects of combined high-protein diet (HPD) loading and 5/6 nephrectomy (Nx) in a susceptible strain of mice (129/Sv). Mice underwent 5/6 Nx or sham surgery, then 2 weeks later were switched to an HPD, and cardiovascular parameters, kidney function, and renal histology were assessed after 4, 8, or 12 weeks. The 5/6 Nx group showed blood pressure elevation, cardiac hypertrophy, renal function decline, severe albuminuria, and glomerular hypertrophy. However, the glomerulosclerosis by 5/6 Nx was very mild and there was only modest tubulointerstitial inflammation and fibrosis in the 5/6 Nx group, even after 12 weeks of HPD loading. Furthermore, the sham group showed no histological changes. Thus, an HPD alone is insufficient to cause renal pathology, and a combination of 5/6 Nx and HPD loading induces mild renal pathology. Therefore, future studies of CKD using 5/6 Nx should be performed over a relatively long period of time in mice, or should be performed in other animals that are susceptible to kidney injury.
Comprehensive Studies on Amino Acid Based Organometallic L-Threoninum Cobalt (Ii) Sulfate (Ltcs) Single Crystal
Authors: SANTHIA S V ASHVIN , ANEEBA B , VINU S , CHRISTY R SHEELA 
Published: March 2021

Abstract
By the most widely used slow evaporation technique at room temperature, L-Threoninum Cobalt (II) Sulfate Heptahydrate (LTCS) materials were grown for various applications. The structure of orthorhombic LTCS was identified by X-Ray Diffraction studies (Powder X-Ray Diffraction and Single crystal X-Ray Diffraction), this analysis has also reported the crystallinity, cell parameters (a = 5.35, b = 7.93, c = 13.71), and space group (non-centrosymmetric) of the grown material. Functional groups were affirmed by FTIR analysis. Optical analysis straightforwardly confirms LTCS crystals has greater optical transparency, and Eg = 5.6 eV demonstrates the appropriateness of prepared crystals to optical applications. The mechanical properties were validated with the aid of Vickers' microhardness measurement and that also suggests LTCS belongs to the class of hard material. In this respect, the SHG efficiency of the LTCS crystal grown is 1.25 times greater than that of the KDP crystal because Co+ ions boost the SHG efficiency of LTCS and it was tested by Kurtz and Perry's technique. Electrical results documented the good conducting properties of LTCS crystal. The LTCS substance used to treat fungal and bacterial infections and this bacterial and fungal destroying property was validated by an antimicrobial assay.
RNA-Seq Profiling Revealed PBMC RNA as Potential Biomarker for Hepatocellular Carcinoma
Authors: Han Zhiyi , Feng Wenxing , Hu Rui , Ge Qinyu , Ma Wenfeng , Zhang Wei , Xu Shaomin , Zhan Bolin , Zhang Lai , Sun Xinfeng , Zhou Xiaozhou 
Published: March 2021

Abstract
Background: Hepatocellular carcinoma with extremely high morbidity and mortality is one of the most common malignant tumors. Although many existing studies focus on the study of its biomarkers, little information has been released on the PBMC RNA profile of hepatocellular carcinoma. Methods: We tried to make a profile throughout this analysis with the expression of Peripheral Blood Mononuclear Cells (PBMCs) RNA by using RNA-seq technology and compared the transcriptome between hepatocellular carcinoma patients and the healthy controls. 17 patients and 17 healthy controls involved in this study, PBMCs RNA were sequenced. The sequencing data were analyzed with bioinformatics tools and qRT-PCR was used for selected differential expressed gene validation. Results: It is showed that 1578 dysregulated genes found including 1334 upregulated genes and 244 downregulated genes. GO enrichment and KEGG studies showed that hepatocellular carcinoma is a closely linked source of the most differentially expressed genes (DEGs), implicated in the immune response. Expression of the 6 selected genes (SELENBP1, SLC4A1, SLC26A8, HSPA8P4, CALM1, and RPL7p24) were confirmed by qRT-PCR, and higher sensitivity and specificity obtained by ROC analysis of the 6 genes. CALM1 was found gradually decreasing along with the tumor enlarged. Conclusions: It is suggested potential biomarker for diagnosis of hepatocellular carcinomas. This study provided new perspectives for liver cancer development and possible future successful clinical diagnosis.
Two Areas and One Passage: A Simplified Protocol for the Transformation of General Hospitals to Infectious Disease Hospitals Upon the Pandemic Outbreak
Authors: Yin Jikai , Li Dongdong , Peng Meijuan , Guo Wangang 
Published: March 2021

Abstract
Infectious disease hospitals and wards fell far short of demand after the COVID-19 pandemic outbroke. Consequently, it was of urgent importance to transform existing general wards into temporary infectious disease wards for COVID-19 patients. However, due to the limitations of the original structure of public hospitals, general wards could not meet the structural criteria requiring “three areas, two passages, and two hallways” for receiving infectious disease patients. In this article, we present a “Two Areas and One Passage” reconstruction and working protocol, which has been proved to be safe and easy to achieve by medical staff during the epidemic of COVID-19 in 2020. This protocol tremendously helps to save workforce and personal protective equipment compared with standard transformation protocol and thus might be used as an exemplary protocol for the transformation of general hospitals to infectious disease hospitals upon pandemic outbreak. Besides, it also provide a new scope for us to transform the general hospital to military infectious disease hospital if there occur abundant infectious disease suffers in the battlefield.
Comparison of Short-term Surgical Outcomes Using Da Vinci S, Si and Xi Surgical System for Robotic Gastric Cancer Surgery
Authors: Ojima Toshiyasu , Nakamura Masaki , Hayata Keiji , Kitadani Junya , Takeuchi Akihiro , Yamaue Hiroki 
Published: March 2021

Abstract
When compared with the second/third generation da Vinci S/Si, the fourth generation Xi surgical system may allow for greater efficiency and result in shorter operation times during robotic gastrectomy (RG) for gastric cancer (GC). We directly compare surgical outcomes between the conventional S/Si and the newer Xi robotic platform for the treatment of GC. This is a single-center retrospective study of 148 consecutive patients with GC who underwent RG. Of these patients, 20 patients were treated with the S, 30 patients with the Si, and 98 patients with the Xi. The overall operation time was significantly longer in the S group (386.5 min) than in the other groups (Si group: 292 min; Xi group: 297 min) (S vs. Si: P = 0.010; S vs. Xi: P = 0.001). We observed no difference, however, between the newer Xi and Si systems in operation time. Intraoperative blood loss was similar across the three groups. The overall postoperative complication rate in the Xi group (8.2%) was lower than that of the S group (10%) and the Si group (13.3%), but the difference was not significant. The newer Xi system did not provide significant intraoperative or early postoperative advantages over the Si system.
A photogrammetric and cephalometric evaluation of facial symmetry and smile in relation to attractiveness.
Authors: Akshita  , Chauhan Arun K. , Chawla Riddhi 
Published: March 2021

Introduction: Human find symmetrical face more attractive than are asymmetrical faces. The smile is one of the most important facial expressions and is essential in expressing friendliness, agreement, and appreciation. The aim of the present study was to evaluate the relationship between smile and symmetry in attributing to attractiveness.

Materials & Method: The study was conducted in the Department Of Orthodontics and Dentofacial Orthopedics, on 150 samples. 150 good quality radiographs and photographs of the patients were obtained. The subjects were divided into three groups: Group I – Horizontal growth pattern Group II – Average growth pattern Group III – Vertical growth pattern. The frontal facial photograph and PA cephalometric radiograph were used to assess the facial symmetry. Posed smile photograph and Lateral cephalometric radiograph were used to assess the smile. Digimizer Image Analyzer (bvba software) were used for the analysis. The ratings were given by the expert panellist based on attractiveness

Results: In the present study, Left facial symmetry parameters is marginally higher than right side in cephalometric analysis and converse for photographic analysis, right facial symmetry parameters is marginally higher than left side but this is not statistically significant. There are no statistically significant difference among the groups for smile -photographic parameters and lateral cephalometric smile parameters. There is statistically significant difference among the groups for Visual Analog Scale readings for attractiveness given by orthodontist, general dentist and layperson for frontal profile for the subjects of three study groups.

Conclusion: The study revealed that in cephalometric analysis, left hemiface is wider than right hemiface while in photographic analysis, right hemiface is wider than left hemiface. Vertical grower shows maximum upper incisor exposure and upper and lower vermilion lip thickness. On the contrary full smile length was minimum in vertical grower. The most favored profile by VAS was horizontal growth pattern.
Prevalence and aetiology of dental trauma in 8-14 year old school-going children of Hyderabad city, India
Authors: Ahmed Tanzeem , Kaushal Nikhil , Singh Sujeet , Agarwal Rashmi 
Published: March 2021

Aims and Objectives: To determine the prevalence and etiology of fractured anterior teeth due to trauma among 8–14 years old school going children of Hyderabad city.
Materials and method: A cross-sectional study was carried out in 8-14 year old children studying in various schools of Hyderabad for the assessment of traumatic injuries of anterior teeth. Clinical examination was carried out and type of teeth affected, type of fracture, overjet and lip competence were noted. A closed end questionnaire was given to children with questions regarding etiology of trauma, place of injury, symptoms or outcomes after the injury, whether a dentist was consulted, type of treatment done by dentist and time elapsed between trauma and treatment. All the results were analyzed using “statistical package for social sciences” (SPSS) 20.0 software.
Results: The prevalence of dental trauma was found to be 7.84%. 11-14year old children showed higher prevalence. Males were more affected than females. Maxillary central incisors were most affected. Fracture involving enamel and dentin were recorded the highest. Children having overjet of >3mm and incompetent lips were at a higher risk of dental trauma (p value = 0.001). The most common cause of injury was sports and home was the most common place of occurrence of injury. Most of the traumatic dental injuries (TDI) did not undergo any treatment.
Conclusion: Increasing the awareness of the parents and teachers about the prevention of TDI and the importance of consulting the dentist after trauma should be instituted.
Effect of different mouth washes as a pre-procedural rinse to combat aerosol contamination– A cross-sectional study
Authors: Warad Shivaraj , Bhatagunaki Ravi  V 
Published: March 2021

Background: Ultrasonic scaling is a potent source of aerosol generation in dental offices, thus causing increase risk of bacterial infections. Pre-procedural mouth rinsing has been found effective in reducing the bacterial load of the aerosol produced during the procedure. Aim and objectives: the aim of the present study was to evaluate and compare the efficacy of two different mouthwashes containing Chlorhexidine and Octenidine with distilled water, by using them as preprocedural rinsing agents in reducing the bacterial load of the aerosol produced by ultrasonic scaler. Materials and Methods: 80 subjects aged 18-35years were randomly divided into three groups on the basis of mouth rinses used for preprocedural mouthrinsing - Group 1: Distilled Water (Control), Group 2: 0.2% Chlorhexidine (CHX), Group 3: 0.1% Octenidine. The aerosols were collected on agar plates placed and stabilized on patient’s as well as on operator’s chest. all the agar plates were sent for microbiological analysis to the microbiological laboratory for Colony Forming Unit (CFU) count on the same day of ultrasonic scaling procedure. The data obtained was subjected to the statistical analysis using SPSS software version 20.0. Result: At all locations, the mean CFU was significantly highest in Group I, followed by Group II and Group III. It was observed that aerosol generation on patients was significantly more than operator. Conclusion: In our study 0.1% octenidine was found to be most effective preprocedural mouthwash in reducing the bacterial load in the aerosol produced during ultrasonic scaling followed by 0.2% chlorhexidine and distilled water.
BIOMASSA SECA ESTIMADA EM ÁREAS DE PASTAGENS COM DADOS DE SENSORIAMENTO REMOTO: Estudo de caso na bacia hidrográfica do Rio Vermelho - Goiás
Authors: Alves Veloso Gabriel , Rêgo Silva Janete , Ferreira Manuel Eduardo , Guimarães Ferreira Júnior Laerte 
Published: March 2021

Objetivo deste trabalho foi estimar a biomassa seca em áreas de pastagens com dados satelitários, bem como dados de campo em áreas de pastagem no Cerrado goiano. O experimento foi realizado em áreas de pastagens na Bacia Hidrográfica do Rio Vermelho, porção oeste de Goiás, com a utilização das imagens do satélite Landsat 8. A estimativa deste parâmetro foi obtida combinando os algoritmos SEBAL (Surface Energy Balance Algorithm for Land), e o modelo CASA (Carnegie Ames Stanford Approach). Dentre os resultados, a análise da biomassa seca apresentou melhor resultado com o método SEBAL/CASA. Portanto, a estimativa da biomassa seca da pastagem com dados climáticos locais, bem com a calibração dos modelos com dados biofísicos específicos apresentou bons resultados.
Palavras-chaves: Pastagem; Landsat 8; Cerrado; Modelagem
RELAÇÃO ENTRE OS CASOS DE DENGUE E O MÉTODO DE PROFILAXIA DE OVITRAMPAS NO MUNICÍPIO DE GOIÂNIA
Authors: Rosa Lucas Espíndola , Pantaleão Ana Maria , Nunes Elizon Dias , Cherem Luís Felipe Soares 
Published: March 2021

A dengue é uma doença com ocorrência no estado de Goiás desde 1994. A partir de 2018 foi adotado na cidade de Goiânia um novo método no combate profilático, que é o estabelecimento das ovitrampas. Deste modo, o objetivo deste trabalho é compreender a relação entre os casos de ocorrência de dengue com a distribuição das ovitrampas no município de Goiânia. A pesquisa conta com o estabelecimento de 43 ovitrampas, distribuídas nas 7 regiões administrativas da capital, perfazendo um total de cobertura de 212 bairros dos 504 existentes. Os resultados apontam que as ovitrampas contribuem para a diminuição dos casos de dengue, sendo que a região Leste da capital é que apresenta maiores casos de notificações no ano de 2018, sendo os meses de março, abril e maio os de maior ocorrência. Até o mês de março de 2019, a capital apresenta 50% dos casos em comparação com o ano total de 2018
«La querella de los novelistas. La lucha por la memoria en la literatura española (1990-2010)», de Sara Santamaría Colmenero
Authors: Prieto Javier Alonso 
Published: March 2021

Reseña del libro La querella de los novelistas. La lucha por la memoria en la literatura española (1990-2010) (Valencia, Prensas Universitat de València, 2020), de Sara Santamaría Colmenero
IMPLICATIONS OF HAROA TRADITIONAL PRACTICES IN RELIGIOUS LIFE OF MUNA PEOPLE IN MUNA DISTRICT
Authors: Suraya Rahmat Sewa , Kumbara A.A. Ngurah Anom , Pujaastawa Ida Bagus Gde , Wiasti Ni Made 
Published: March 2021

This study aims to reveal and explain the representation of religious values ??in the practice of haroa and the relationship between cultural practices (haroa) in the diversity of the Muna people. This study uses ethnographic methods with qualitative analysis. Empirically, this research finds that in their daily life, the Muna people make religion and culture coexist in the midst of their religious social activities. Traditions and cultures that live earlier in society actually already have civilization and social rules so that when Islam developed in the life order of the Muna people there was not much change. This tradition becomes a medium in broadcasting and teaching the values ??of virtue in the teachings of Islam. The haroa tradition carried out by the Muna people from generation to generation when commemorating the Muslim holidays is the most effective medium in teaching all the commands and prohibitions of Allah SWT. The haroa tradition supports the Islamic ideology of the Muna community that hansuru-hansuru adhati, soano konohansuru, which implies that even though customs and traditions are destroyed, religion must not be destroyed. The haroa tradition for the Muna community is to emphasize always making the principles of Islam a life shield so that in every activity they always represent the values ??of Islamic teachings.
Key words: Islam, tradition, haroa, civilization, practice
Efektivitas Sistem Informasi Akuntansi, Budaya Organisasi dan Kinerja Karyawan di Lembaga Perkreditan Desa Kecamatan Tegalalang
Authors: Dwipayana I Gusti Ngurah Krisna , Suputra I Dewa Gede Dharma 
Published: March 2021

Employee performance is a level of overall success for a person in carrying out a task. Good employee performance is driven by the effectiveness of the accounting information system and organizational culture. The purpose of this study was to provide empirical evidence in the effect of the effectiveness of accounting information systems and organizational culture on employee performance. This research conducted at the Village Credit Institutions in Tegalalang District. The number of respondent taken was 121 employees, with a purposive sampling method. Data collection was carried out using a questionnaire. The analysis technique used is multiple linear regression. The results showed that the effectiveness of the accounting information system and organizational culture had a positive effect on employee performance.
Keywords: Effectiveness of Accounting Information Systems; Organizational Culture; Employee Performance.
Faktor-Faktor yang Mempengaruhi Fenomena Ketepatwaktuan Publikasi Laporan Keuangan
Authors: Anggita Dwiantari Ni Kadek , Mediatrix Ratna Sari Maria 
Published: March 2021

Timeliness is needed to present relevant information. In order for a company to submit its financial reports to the public on time, it must consider the factors that affect the timeliness of the publication of financial reports. This study was done to examine the effect of company size, company age as well as independent commissioners on the timeliness of the publication of financial reports. The research was done at food and beverage sub-sector manufacturing companies listed on the Indonesia Stock Exchange at 2017-2019. The samples were 48 companies and used purposive sampling technique. The technique used was logistic analysis. The result indicated that company size and independent commissioners have a positive effect on the timeliness of the publication of financial reports. Meanwhile the age of the company had no effect on the timeliness of the publication of financial reports.
Keywords: Timeliness; Company Size; Company Age; Independent Commissioner.
Analisis Faktor-Faktor yang Mempengaruhi Kinerja Sistem Informasi Akuntansi pada Lembaga Perkreditan Desa
Authors: Safitri Gita Najmi , Dwiana Putra I Made Pande 
Published: March 2021

This study aims to determine the effect of user involvement variables in system development, user education and training programs, personal technical skills, user communication and information systems developers and organizational size on the performance of the Accounting Information System. Respondents in this study were 40 employees found in the LPD in South Denpasar District. Determination of the sample using purposive sampling method. The analytical tool used is multiple regression analysis. The results of this study indicate that the variables of user involvement in system development, user training and education programs, personal technical skills, user communication and information system developers and organizational size have a significant positive effect on SIA performance.
Keywords: User Involvement; Training and Education; Personal Engineering; User and Developer Communication.
Self Efficacy, Partisipasi Anggaran, Asimetri Informasi, Emosional Stability dan Penekanan Anggaran terhadap Senjangan Anggaran
Authors: Ardianti Putu Novia Hapsari , Damayanti Ni Nyoman Sri Rahayu , Prayoga I Made Surya 
Published: March 2021

A budget is an organizational plan stated in a monetary unit and drawn up for a period of time. The process of budgeting can trigger the behavior of budget implementers to conduct budgetary slack due to negative subjective attitudes and norms owned by budget executives. This makes research on the factors that affect the budgeting slack important to be carried out. This study used data collection techniques with questionnaires. All research instruments are valid and reliable. This research has also been freed from the problem of classical assumptions. The results were tested with multiple linear regression analysis. The results showed self-efficacy, budget participation, information asymmetry, and budgetary emphasis influenced the budgetary slack. On the other side emotional stability has no significant effect on the budgetary slack.
Keywords: Self-efficacy; Budget Participation; Information Asymmetry; Emotional stability; Budgetary Emphasis; Budgetary Slack.