bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sample preparation method for metal(loid) contaminant quantitation in rodent hair collected in Yuma County, Arizona
Authors: Credo Jonathan , Chandos Amy , Checinski Camilla , von Hippel Frank A. , Ingram Jani C. 
Published: July 2021

AbstractYuma County, Arizona, is a large agricultural hub of the USA located in the southwestern corner of Arizona on the USA-Mexico border. Year-round use of agrichemicals at a massive scale along with the influx of aquatic contaminants in the Colorado River led to significant levels of environmental pollution and hence exposure risks for people and wildlife. Although hair is a recognized biomarker for metal exposure, there is no universal hair preparation protocol. This study evaluated two digestion methods for metal quantitation using inductively coupled plasma-mass spectrometry (ICP-MS) and three methods for mercury quantitation using cold vapor-atomic absorption spectroscopy (CV-AAS), both employing certified reference materials. The “overnight” and “heating” digestion methods were suitable for ICP-MS, while only the heating method was suitable for CV-AAS. These validated methods will be useful for a variety of human and wildlife assessments of toxic metal(loid) exposure.
Subclinical cardiac damage in cancer patients before chemotherapy
Authors: Fabiani Iacopo , Panichella Giorgia , Aimo Alberto , Grigoratos Chrysanthos , Vergaro Giuseppe , Pugliese Nicola Riccardo , Taddei Stefano , Cardinale Daniela Maria , Passino Claudio , Emdin Michele , Giannoni Alberto 
Published: July 2021

AbstractCancer and cardiovascular diseases, including heart failure (HF), are the main causes of death in Western countries. Several anticancer drugs and radiotherapy have adverse effects on the cardiovascular system, promoting left ventricular dysfunction and ultimately HF. Nonetheless, the relationship between cancer and HF is likely not unidirectional. Indeed, cancer and HF share common risk factors, and both have a bidirectional relationship with systemic inflammation, metabolic disturbances, and neurohormonal and immune activation. Few studies have assessed the impact of untreated cancer on the heart. The presence of an active cancer has been associated with elevated cardiac biomarkers, an initial impairment of left ventricular structure and function, autonomic dysfunction, and reduced exercise tolerance. In turn, these conditions might increase the risk of cardiac damage from chemotherapy and radiotherapy. HF drugs such as beta-blockers or inhibitors of the renin–angiotensin–aldosterone system might exert a protective effect on the heart even before the start of cancer therapies. In this review, we recapitulate the evidence of cardiac involvement in cancer patients naïve from chemotherapy and radiotherapy and no history of cardiac disease. We also focus on the perspectives for an early diagnosis and treatment to prevent the progression to cardiac dysfunction and clinical HF, and the potential benefits of cardioactive drugs on cancer progression.
Design and Validation of the Scientific Data Products for China’s Tianwen-1 Mission
Authors: Tan Xu , Liu Jianjun , Zhang Xiaoxia , Yan Wei , Chen Wangli , Ren Xin , Zuo Wei , Li Chunlai 
Published: July 2021

AbstractThe Tianwen-1 mission is China’s first Mars exploration mission. To complete the scientific objectives of “orbiting, landing, and patrolling” in one mission, thirteen instruments for acquiring multi-disciplinary data are configured. The data products with rich ancillary data and flexible structures will facilitate the data application. To integrate the requirements of experts from disparate disciplines and leverage new information technologies, a complete redesign of data products is promoted in the Tianwen-1 mission. We discuss the whole process of data product generation from the data pipeline design to data validation. We design the various data products according to the application requirements of each data type, including radar echo data, spectrum data, image data, energy spectrum data, magnetic field data, meteorological data, and acoustic data. Since various error sources will exist in the generation chain of the data products, data validation is essential before release to the public; the validation activities are discussed at the end. We deliver these scientific products to the community in a timely manner, with ancillary information and quality information. This paper can provide practical reference for Tianwen-1 data application.
High-accuracy thrust measurements of the EMDrive and elimination of false-positive effects
Authors: Tajmar M. , Neunzig O. , Weikert M. 
Published: July 2021

AbstractThe EMDrive is a proposed propellantless propulsion concept claiming to be many orders of magnitude more efficient than classical radiation pressure forces. It is based on microwaves, which are injected into a closed tapered cavity, producing a unidirectional thrust with values of at least 1 mN/kW. This was met with high scepticism going against basic conservation laws and classical mechanics. However, several tests and theories appeared in the literature supporting this concept. Measuring a thruster with a significant thermal and mechanical load as well as high electric currents, such as those required to operate a microwave amplifier, can create numerous artefacts that produce false-positive thrust values. After many iterations, we developed an inverted counterbalanced double pendulum thrust balance, where the thruster can be mounted on a bearing below its suspension point to eliminate most thermal drift effects. In addition, the EMDrive was self-powered by a battery-pack to remove undesired interactions due to feedthroughs. We found no thrust values within a wide frequency band including several resonance frequencies and different modes. Our data limit any anomalous thrust to below the force equivalent from classical radiation for a given amount of power. This provides strong limits to all proposed theories and rules out previous test results by at least two orders of magnitude.
Interface Engineered Microcellular Magnetic Conductive Polyurethane Nanocomposite Foams for Electromagnetic Interference Shielding
Authors: Sang Guolong , Xu Pei , Yan Tong , Murugadoss Vignesh , Naik Nithesh , Ding Yunsheng , Guo Zhanhu 
Published: July 2021

Abstract
Lightweight microcellular polyurethane (TPU)/carbon nanotubes (CNTs)/ nickel-coated CNTs (Ni@CNTs)/polymerizable ionic liquid copolymer (PIL) composite foams are prepared by non-solvent induced phase separation (NIPS). CNTs and Ni@CNTs modified by PIL provide more heterogeneous nucleation sites and inhibit the aggregation and combination of microcellular structure. Compared with TPU/CNTs, the TPU/CNTs/PIL and TPU/CNTs/Ni@CNTs/PIL composite foams with smaller microcellular structures have a high electromagnetic interference shielding effectiveness (EMI SE). The evaporate time regulates the microcellular structure, improves the conductive network of composite foams and reduces the microcellular size, which strengthens the multiple reflections of electromagnetic wave. The TPU/10CNTs/10Ni@CNTs/PIL foam exhibits slightly higher SE values (69.9 dB) compared with TPU/20CNTs/PIL foam (53.3 dB). The highest specific EMI SE of TPU/20CNTs/PIL and TPU/10CNTs/10Ni@CNTs/PIL reaches up to 187.2 and 211.5 dB/(g cm−3), respectively. The polarization losses caused by interfacial polarization between TPU substrates and conductive fillers, conduction loss caused by conductive network of fillers and magnetic loss caused by Ni@CNT synergistically attenuate the microwave energy.
An Active Set Trust-Region Method for Bound-Constrained Optimization
Authors: Kimiaei Morteza 
Published: July 2021

AbstractThis paper discusses an active set trust-region algorithm for bound-constrained optimization problems. A sufficient descent condition is used as a computational measure to identify whether the function value is reduced or not. To get our complexity result, a critical measure is used which is computationally better than the other known critical measures. Under the positive definiteness of approximated Hessian matrices restricted to the subspace of non-active variables, it will be shown that unlimited zigzagging cannot occur. It is shown that our algorithm is competitive in comparison with the state-of-the-art solvers for solving an ill-conditioned bound-constrained least-squares problem.
Post-truth Politics and Collective Gaslighting
Authors: Rietdijk Natascha 
Published: July 2021

AbstractPost-truth politics has been diagnosed as harmful to both knowledge and democracy. I argue that it can also fundamentally undermine epistemic autonomy in a way that is similar to the manipulative technique known as gaslighting. Using examples from contemporary politics, I identify three categories of post-truth rhetoric: the introduction of counternarratives, the discrediting of critics, and the denial of more or less plain facts. These strategies tend to isolate people epistemically, leaving them disoriented and unable to distinguish between reliable and unreliable sources. Like gaslighting, post-truth politics aims to undermine epistemic autonomy by eroding someone's self-trust, in order to consolidate power. Shifting the focus to the effects on the victim allows for new insights into the specific harms of post-truth politics. Applying the concept of gaslighting to this domain may also help people recognize a pernicious dynamic that was invisible to them before, giving them an important tool to resist it.
Regression discontinuity designs: a hands-on guide for practice
Authors: Valentim Vicente , Ruipérez Núñez Ana , Dinas Elias 
Published: July 2021

AbstractRegression discontinuity (RD) designs have become increasingly popular in political science, due to their ability to showcase causal effects under weak assumptions. This paper provides an intuition-based guide for the use of the RD in applied research. After an intuitive explanation of how the method works, we provide a checklist that can help researchers understand the main robustness checks they should run, and a quick introduction to software implementing the design. We also provide a list of classic designs and examples of their application in political science. We hope this article can constitute a stepping stone from which researchers interested in RD can jump to more advanced literature; and which makes researchers not interested in implementing RDs better consumers of research employing this design.
Advancing the RDoC initiative through the assessment of caregiver social processes
Authors: King Lucy S. , Salo Virginia C. , Kujawa Autumn , Humphreys Kathryn L. 
Published: July 2021

AbstractThe relationships infants and young children have with their caregivers are fundamental to their survival and well-being. Theorists and researchers across disciplines have attempted to describe and assess the variation in these relationships, leading to a general acceptance that caregiving is critical to understanding child functioning, including developmental psychopathology. At the same time, we lack consensus on how to assess these fundamental relationships. In the present paper, we first review research documenting the importance of the caregiver–child relationship in understanding environmental risk for psychopathology. Second, we propose that the National Institute of Mental Health's Research Domain Criteria (RDoC) initiative provides a useful framework for extending the study of children's risk for psychopathology by assessing their caregivers’social processes. Third, we describe the units of analysis for caregiversocial processes,documenting how the specific subconstructs in the domain ofsocial processesare relevant to the goal of enhancing knowledge of developmental psychopathology. Lastly, we highlight how past research can inform new directions in the study of caregiving and the parent–child relationship through this innovative extension of the RDoC initiative.
Impact of brain-derived neurotrophic factor Val66Met polymorphism and response to escitalopram or paroxetine in obsessive–compulsive disorder
Authors: Harika-Germaneau Ghina , Langbour Nicolas , Patri Sylvie , Solinas Marcello , Chatard Armand , Millet Bruno , Hashemian Farshad , Pérault-Pochat Marie-Christine , Jaafari Nematollah , Lafay-Chebassier Claire 
Published: July 2021

AbstractObjectiveObsessive–compulsive disorder (OCD) is a severe psychiatric disorder characterized by its heterogeneous nature and by different dimensions of obsessive–compulsive (OC) symptoms. Serotonin reuptake inhibitors (SRIs) are used to treat OCD, but up to 40% to 60% of patients do not show a significant improvement with these medications. In this study, we aimed to test the impact of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism on the efficacy of antidepressants in OCD overall, and in relation to the different OC dimensions.MethodsIn a 6-month prospective treatment study, 69 Caucasian OCD patients were treated with escitalopram for 24 weeks or with escitalopram for 12 weeks followed by paroxetine for an additional 12-week period. Patients were genotyped and assessed for treatment response. The main clinical outcomes were improvement of the Yale-Brown Obsessive–Compulsive Scale score and in different OC symptom dimension scores.ResultsThe Val/Val group comprised 43 (62%) patients, the Val/Met and Met/Met group comprised 26 (38%) patients. Forty-two patients were classified as responders at 12 weeks and 38 at 24 weeks; no significant association was found between BDNF Val66Met and SRIs response at 12 and 24 weeks. In analyses of the different OC symptom dimensions, the Met allele was associated with a slightly reduced score in the aggressive/checking dimension at 6 months (P = .048).ConclusionsOur findings do not support the usefulness of BDNF Val66Met genotyping to predict overall response to treatment with SRIs in OCD; they did however suggest a better outcome at 6 months for the aggressive/checking symptom dimension for patients carrying the Met allele.
Australia's Response to COVID-19
Authors: Stobart Anika , Duckett Stephen 
Published: July 2021

AbstractAustralia suffered two waves of the coronavirus disease 2019 pandemic in 2020: the first lasting from February to July 2020 was mainly caused by transmission from international arrivals, the second lasting from July to November was caused by breaches of hotel quarantine which allowed spreading into the community. From a second wave peak in early August of over 700 new cases a day, by November 2020 Australia had effectively eliminated community transmission. Effective elimination was largely maintained in the first half of 2021 using snap lockdowns, while a slow vaccination programme left Australia lagging behind comparable countries. This paper describes the interventions which led to Australia's relative success up to July 2021, and also some of the failures along the way.
Re‐Analysis of the Cassini RPWS/LP Data in Titan's Ionosphere: 2. Statistics on 57 Flybys
Authors: Chatain A. , Wahlund J.‐E. , Shebanits O. , Hadid L. Z. , Morooka M. , Edberg N. J. T. , Guaitella O. , Carrasco N. 
Published: July 2021

AbstractThe ionosphere of Titan hosts a complex ion chemistry leading to the formation of organic dust below 1,200 km. Current models cannot fully explain the observed electron temperature in this dusty environment. To achieve new insight, we have re‐analyzed the data taken in the ionosphere of Titan by the Cassini Langmuir probe (LP), part of the Radio and Plasma Wave Science package. A first paper (Chatain et al., 2021) introduces the new analysis method and discusses the identification of four electron populations produced by different ionization mechanisms. In this second paper, we present a statistical study of the whole LP dataset below 1,200 km which gives clues on the origin of the four populations. One small population is attributed to photo‐ or secondary electrons emitted from the surface of the probe boom. A second population is systematically observed, at a constant density (∼500 cm−3), and is attributed to background thermalized electrons from the ionization process of precipitating particles from the surrounding magnetosphere. The two last populations increase in density with pressure, solar illumination and Extreme ultraviolet flux. The third population is observed with varying densities at all altitudes and solar zenith angles (SZA) except on the far nightside (SZA > ∼140°), with a maximum density of 2,700 cm−3. It is therefore certainly related to the photo‐ionization of the atmospheric molecules. Finally, a fourth population detected only on the dayside and below 1,200 km reaching up to 2000 cm−3 could be photo‐ or thermo‐emitted from dust grains.
Investigating Axisymmetric and Asymmetric Signals of Secondary Eyewall Formation Using Observations‐Based Modeling of the Tropical Cyclone Boundary Layer
Authors: Yu Chau‐Lam , Didlake Anthony C. , Kepert Jeffrey D. , Zhang Fuqing 
Published: July 2021

AbstractThis study examines axisymmetric and asymmetric aspects of secondary eyewall formation (SEF) in tropical cyclones (TCs) by applying a nonlinear boundary layer model to tangential wind composites of observed TCs with and without SEF. SEF storms were further analyzed at times prior to and after SEF, as defined by the emergence of a secondary maximum in axisymmetric tangential wind. The model is used to investigate the steady‐state boundary layer response to the free‐tropospheric pressure forcing derived from observed tangential wind fields. The axisymmetric response to the Post‐SEF wind field displayed a secondary updraft maximum associated with a mature secondary eyewall; the model correctly produced no secondary updraft for non‐SEF storms. The Pre‐SEF response also exhibited a secondary updraft associated with an incipient secondary eyewall largely due to the broadened outer tangential wind field that commonly precedes SEF events. The asymmetric wind fields and model response were analyzed relative to the 850–200 hPa environmental wind shear vector. In Pre‐SEF storms, the tangential wind field displayed a broadened tangential wind structure in the downshear quadrants. The boundary layer response shows a downwind shift toward the left‐of‐shear quadrants, exhibiting the clearest secondary maxima in updrafts, tangential wind, and radial inflow. This left‐of‐shear response was the leading contributor to the secondary eyewall signals in the Pre‐SEF axisymmetric response. Sensitivity analyses confirmed the robustness of these asymmetric signals. These findings suggest that enhanced tangential wind and boundary layer updrafts in the left‐of‐shear sectors may be early indicators and critical features of SEF in sheared TCs.
Fault Planes, Fault Zone Structure and Detachment Fragmentation Resolved With High‐Precision Aftershock Locations of the 2016–2017 Central Italy Sequence
Authors: Waldhauser Felix , Michele Maddalena , Chiaraluce Lauro , Di Stefano Raffaele , Schaff David P. 
Published: July 2021

AbstractThree devastating earthquakes of MW ≥ 5.9 activated a complex system of high‐angle normal, antithetic, and sub‐horizontal detachment faults during the 2016–2017 central Italy seismic sequence. Waveform cross‐correlation based double‐difference location of nearly 400,000 aftershocks illuminate complex, fine‐scale structures of interacting fault zones. The Mt. Vettore–Mt. Bove (VB) normal fault exhibits wide and complex damage zones, including a system of bookshelf faults that intersects the detachment zone. In the Laga domain, a comparatively narrow, shallow dipping segment of the deep Mt. Gorzano fault progressively ruptures through the detachment zone in four subsequent MW ∼ 5.4 events. Reconstructed fault planes show that the detachment zone is fragmented in four sub‐horizontal, partly overlaying shear planes that correlated with the extent of the mainshock ruptures. We find a new, deep reaching seismic barrier that coincides with a bend in the VB fault and may play a role in controlling rupture evolution.
Inter‐Basin Interaction Between Variability in the South Atlantic Ocean and the El Niño/Southern Oscillation
Authors: Ham Yoo‐Geun , Lee Hyun‐Jeong , Jo Hyun‐Su , Lee Se‐Gun , Cai Wenju , Rodrigues Regina R. 
Published: July 2021

AbstractOceanic variability that interacts with the El Niño/Southern Oscillation (ENSO) has been well identified in most ocean basins; however, the effect of variability over the South Atlantic (SA) on the ENSO is unknown. This study demonstrates that dominant mode of subtropical SA sea surface temperature (SST) variability during the boreal winter, referred to as the South Atlantic Subtropical Dipole (SASD), contributes to occurrence of an El Niño a year later. During a positive SASD, low‐tropospheric anticyclonic circulation anomalies over the mid‐latitude SA reduce convective activities over southeastern South America. The low‐tropospheric divergence anomalies associated with the reduced convection attenuate the occurrence of South American Low‐Level Jet, and moisture supply is directed along the South Atlantic Convergence Zone (SACZ). The increased precipitation over the SACZ leads to an anomalous surface easterly that lowers the SST over the equatorial Atlantic and eventually modulates the zonal Walker circulation, thereby favoring El Niño development.
Decadal Timescale Correlations Between Global Earthquake Activity and Volcanic Eruption Rates
Authors: Jenkins A. P. , Biggs J. , Rust A. C. , Rougier J. C. 
Published: July 2021

AbstractAt the global scale, large tectonic earthquakes and volcanic eruptions are believed to be random and independent events. Here, we compare global time‐series of large earthquakes ( 7) and explosive volcanic eruptions (VEI 2) spanning 1960–2019. Both time‐series exhibit decadal timescale trends, over which annual earthquake and eruption rates vary by a factor of 2. Moreover, global seismic moment release is positively correlated with global eruption rate, with Monte Carlo permutation tests showing that this correlation is significant with a ‐value of 0.05. Although large earthquakes can trigger eruptions at nearby volcanoes, the magnitude of this effect is insufficient to cause the observed global correlation. Other mechanisms, such as triggering of distant eruptions (>1000 km) by earthquake‐induced dynamic stress changes, modulation of global earthquake and eruption rates by variations in Earth's rotational velocity, or natural synchronization of events over repeating cycles, are therefore required to explain the correlation.
Antarctic Radiative and Temperature Responses to a Doubling of CO2
Authors: Freese Lyssa M. , Cronin Timothy W. 
Published: July 2021

AbstractGreenhouse gases (GHGs), including carbon dioxide (), impact global and local outgoing longwave radiation (OLR). The Antarctic is known for its near‐surface temperature inversion, where the addition of GHGs can lead to increased OLR during all but the winter months. These changes in OLR, however, are unable to explain modeled surface warming due to changes in GHGs across central Antarctica. Here we develop a simple explanation showing why adding always warms the surface, and allowing an estimation of the change in surface temperature due to a change in concentration based on the initial surface temperature. We develop a radiative‐advective‐turbulent single‐column model based on observed temperatures for explicit comparisons between our estimations and model equilibrium behavior. We confirm that Antarctic surface temperatures warm as GHG concentrations increase, and find that this response is best explained through the surface greenhouse effect rather than that of the top of atmosphere (TOA).