bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘Dinosaur-bird’ macroevolution, locomotor modules and the origins of flight
Authors: Nebreda Sergio M. , Hernández Fernández Manuel , Marugán-Lobón Jesús 
Published: August 2021

AbstractThe dinosaurian origin of birds is one of the best documented events that palaeontology has contributed to the understanding of deep time evolution. This transition has been studied on multiple fossils using numerous multidisciplinary resources, including systematics, taxonomic, anatomical, morphological, biomechanical and molecular approaches. However, whereas deep time origins and phylogenetic relationships are robust, important nuances of this transition’s dynamics remain controversial. In particular, the fossil record of several maniraptoran groups clearly shows that aerial locomotion was developed before an ‘avialization’ (i.e., before the first divergence towards avialans), thus earlier than presumed. Although aspects as important as miniaturization and the acquisition of several anatomical and morphological modifications are key factors determining such evolutionary transition, understanding this macroevolutionary trend also involves to seize the evolution of developmental systems, which requires assessing the morphological expression of integration and modularity of the locomotor apparatus throughout time. This is so because, as it happened in other flying vertebrate taxa such as pterosaurs and bats, the transformation of the maniraptoran forelimbs into flying locomotor modules must not only have involved a gradual anatomical transformation, but also a complete developmental re-patterning of the integration scheme between them and the hindlimbs. Here, we review the most relevant aspects of limb morphological transformation during the so-called ‘dinosaur-bird’ transition to stress the importance of assessing the role of modularity and morphological integration in such macroevolutionary transition, which ultimately involves the origins of flight in dinosaurs.
Digital 3D models of theropods for approaching body-mass distribution and volume
Authors: Reolid Matías , Cardenal Francisco J. , Reolid Jesús 
Published: August 2021

AbstractThe aim of this work is to obtain diverse morphometric data from digitized 3D models of scientifically accurate palaeoreconstructions of theropods from eight representative families. The analysed polyvinyl chloride (PVC) models belong to the genera Coelophysis, Dilophosaurus, Ceratosaurus, Allosaurus, Baryonyx, Carnotaurus, Giganotosaurus, and Tyrannosaurus. The scanned 3D models were scaled considering different body-size estimations of the literature. The 3D analysis of these genera provides information on the skull length and body length that allows for recognition of major evolutionary trends. The skull length/body length in the studied genera increases according with the size of the body from the smallest Coelophysis with a ratio of 0.093 to ratios of 0.119–0.120 for Tyrannosaurus and Giganotosaurus, the largest study theropods. The study of photogrammetric 3D models also provides morphometric information that cannot be obtained from the study of bones alone, but knowing that all reconstructions begin from the fossil bones, such as the surface/volume ratio (S/V). For the studied theropod genera surface/volume ratio ranges from 35.21 for Coelophysis to 5.55 for Tyrannosaurus. This parameter, closely related to the heat dissipation, help in the characterization of the metabolism of extinct taxa. Accordingly, slender primitive forms of the Early Jurassic (i.e. Coelophysis and Dilophosaurus) had relatively smaller skulls and higher mass-specific metabolic rates than the robust large theropods of the Cretaceous (i.e. Giganotosaurus and Tyrannosaurus). This work presents a technique that, when applied to proper dinosaur models, provides extent and accurate data that may help in diverse study areas within the dinosaur palaeontology and palaeobiology.
Paramedics assessing patients with complex comorbidities in community settings: results from the CARPE study
Authors: Leyenaar Matthew S. , McLeod Brent , Jones Aaron , Brousseau Audrey-Anne , Mercier Eric , Strum Ryan P. , Nolan Michael , Sinha Samir K. , Agarwal Gina , Tavares Walter , Costa Andrew P. 
Published: August 2021

Abstract
Objectives
The aim for this study was to provide information about how community paramedicine home visit programs best “navigate” their role delivering preventative care to frequent 9-1-1 users by describing demographic and clinical characteristics of their patients and comparing them to existing community care populations.

Methods
Our study used secondary data from standardized assessment instruments used in the delivery of home care, community support services, and community paramedicine home visit programs in Ontario. Identical assessment items from each instrument enabled comparisons of demographic, clinical, and social characteristics of community-dwelling older adults using descriptive statistics and z-tests.

Results
Data were analyzed for 29,938 home care clients, 13,782 community support services clients, and 136 community paramedicine patients. Differences were observed in proportions of individuals living alone between community paramedicine patients versus home care clients and community support clients (47.8%, 33.8%, and 59.9% respectively). We found higher proportions of community paramedicine patients with multiple chronic disease (87%, compared to 63% and 42%) and mental health-related conditions (43.4%, compared to 26.2% and 18.8% for depression, as an example).

Conclusion
When using existing community care populations as a reference group, it appears that patients seen in community paramedicine home visit programs are a distinct sub-group of the community-dwelling older adult population with more complex comorbidities, possibly exacerbated by mental illness and social isolation from living alone. Community paramedicine programs may serve as a sentinel support opportunity for patients whose health conditions are not being addressed through timely access to other existing care providers.

Protocol registration
ISRCTN 58273216.
A quantitative method for deriving salinity of subglacial water using ground-based transient electromagnetics
Authors: Killingbeck Siobhan F. , Dow Christine F. , Unsworth Martyn J. 
Published: August 2021

AbstractLiquid water can exist at temperatures well below freezing beneath glaciers and ice sheets, where subglacial water systems, fresh and saline, have been shown to host unique microbial ecosystems. Geophysical techniques sensitive to fluid-content contrasts, e.g. electromagnetics, can characterize subglacial water and its salinity. Here, we assess the ground-based transient electromagnetic (TEM) method for deriving the resistivity and salinity of subglacial water. We adapt an existing open-source Bayesian inversion algorithm, which uses independent depth constraints, to output posterior distributions of resistivity and pore fluid salinity with depth. A variety of synthetic models, including a thin (5 m), conductive (0.16 Ωm), hypersaline (147 psu) subglacial lake, are used to evaluate the TEM method for imaging under 800 m-thick ice. The study demonstrates that TEM methods can resolve conductive, saline bodies accurately using external depth constraints, for example, from radar or seismic data. The depth resolution of TEM can be limited beneath deep (>800 m), thick (>50 m) conductive, water bodies and additional constraints from passive electromagnetic (EM) methods could be used to reduce ambiguities in the TEM results. Subsequently, non-invasive active and passive EM methods could provide profound insights into remote aqueous systems under glaciers and ice sheets.
Permian–Triassic phylogenetic and morphologic evolution of rhynchonellide brachiopods
Authors: Guo Zhen , Chen Zhong-Qiang , Harper David A. T. , Huang Yuangeng 
Published: August 2021

AbstractThe Rhynchonellida is a major group of brachiopods that survived the “big five” mass extinctions and flourished after the Permian/Triassic (P/Tr) crisis. However, phylogenetic and character evolution in the Rhynchonellida across the P/Tr transition is poorly understood. In view of the widespread homoplasy across this order, we employ a tip-dated Bayesian analysis to reconstruct phylogenetic relationships for late Permian–Triassic rhynchonellides. The same data were also analyzed using three other methods: undated Bayesian, equal-weighting, and implied-weighting parsimony. Compared with trees generated by other methods, those constructed by tip-dating best account for the homoplasy in this group and are closer to previous assumptions on the evolution of this order. Based on the analyses of multiple trees, the major increase in lineage richness occurred in the Early and early Middle Triassic. Also, richness in the Anisian almost reached the highest level seen in the Triassic. According to fossil records, a pronounced reduction in shell size and in the development of ornamentation occurred after the P/Tr extinction, which is largely due to the loss of large and highly sculptured genera and the diversification of small-sized and weakly ornamented genera. Ancestral-state estimation of shell size and development of ornamentation, coupled with comparisons of other characters, indicate that the Early–Middle Triassic mature “small-sized taxa” may have characters displayed by juveniles of their ancestors. This suggests that for these genera, paedomorphosis was possibly a strategy to survive and diversify in the harsh environment after the P/Tr extinction.
Online behavioural activation during the COVID-19 pandemic decreases depression and negative affective bias
Authors: Ruzickova Tereza , Carson James , Argabright Stirling , Gillespie Amy , Guinea Calum , Pearse Anna , Barwick Robbie , Murphy Susannah E. , Harmer Catherine J. 
Published: August 2021

AbstractBackgroundThe COVID-19 pandemic highlighted the need for mental health interventions that can be easily disseminated during a crisis. Behavioural activation (BA) is a cost-effective treatment that can be administered by non-specialists; however, it is unclear whether it is still effective during a time of lockdown and social distancing, when opportunities for positive activity are significantly constrained.MethodsBetween May and October 2020, we randomised 68 UK participants with mild to moderate low mood to either a 4-week online programme of non-specialist administered BA or to a passive control group. Before and after the intervention, we collected self-report data on mood and COVID-related disruption, as well as measuring emotional cognition as an objective marker of risk for depression.ResultsIn comparison to the control group, the BA group showed a significant decrease in depression, anxiety and anhedonia after the intervention, as well as an increase in self-reported activation and social support. Benefits persisted at 1-month follow-up. BA also decreased negative affective bias on several measures of the Facial Emotion Recognition Task and early change in bias was associated with later therapeutic gain. Participants rated the intervention as highly acceptable.ConclusionThis study highlights the benefits of online BA that can be administered by non-specialists after brief training. These findings can help inform the policy response towards the rising incidence of mental health problems during a crisis situation such as a pandemic. They also highlight the use of objective cognitive markers of risk across different treatment modalities.
SARS-CoV-2 immunogenicity in individuals infected before and after COVID-19 vaccination: Israel, January–March 2021
Authors: Abu Jabal Kamal , Ben-Amram Hila , Beiruti Karine , Brimat Ira , Abu Saada Ashraf , Bathish Younes , Sussan Christian , Zarka Salman , Edelstein Michael 
Published: August 2021

Abstract
Between December 2020 and March 2021, we measured anti-SARS-CoV-2 IgG titres among 725 Israeli hospital workers vaccinated against COVID-19. Infection post-dose 1 vaccination did not increase IgG titres, and individuals infected post-dose 1 had IgG levels comparable to never-infected individuals who received a single dose, lower than fully vaccinated, never-infected individuals. This suggests dose 2, currently not offered to those infected post-dose 1, may be required in these individuals. Larger studies should confirm whether individuals infected post-dose 1 need the second.
“When the first session may be the last!”: A case report of the implementation of “rapid tele-psychotherapy” with single-session music therapy in the COVID-19 outbreak
Authors: Situmorang Dominikus David Biondi 
Published: August 2021

AbstractObjectiveConventional psychotherapy with a lengthy and regular number of meetings is no longer relevant in the case of COVID-19, when persons with psychiatric problems, especially COVID-19 patients/clients, really require immediate psychological assistance. It is recognized as a “rapid test” in the field of body health to rapidly decide whether or not a person is affected by COVID-19. So, we should now be able to use the term “rapid tele-psychotherapy” with Single-Session Music Therapy (SSMT) in the field of mental health to characterize the mechanism of assistance provided to persons who seek therapeutic assistance virtually during this COVID-19 outbreak, so that they will easily and reliably be freed from troubling psychiatric issues.MethodThe author reports the case of a 33-year-old widow with asymptomatic COVID-19 who was admitted to her own home.ResultsThe author describes the effectiveness of the implementation of rapid tele-psychotherapy with SSMT in reducing the scale of anxiety, panic, fear, depression, acute stress, insomnia, and delusions of death.Significance of resultsThis case can provide new inputs or ideas for counselors/psychologists/psychiatrists/therapists who work in hospitals/institutions to provide rapid tele-psychotherapy with SSMT as therapeutic assistance for individuals who need psychotherapy in this COVID-19 outbreak, especially for COVID-19 patients/clients. Besides that, this concept is not only suitable for rapidly screening individuals that may face psychological problems and helping them better seek therapeutic assistance, but can also be used as an adjuvant therapy for psychiatric patients.
The Fine‐Scale Magnetic History of the Allende Meteorite: Implications for the Structure of the Solar Nebula
Authors: Fu Roger R. , Volk Michael W. R. , Bilardello Dario , Libourel Guy , Lesur Geoffroy R. J. , Ben Dor Oren 
Published: August 2021

AbstractMagnetic fields in the early solar system may have driven the inward accretion of the protoplanetary disk (PPD) and generated instabilities that led to the formation of planets and ring and gap structures. The Allende carbonaceous chondrite meteorite records a strong early solar system magnetic field that has been interpreted to have a PPD, dynamo, or impact‐generated origin. Using high‐resolution magnetic field imaging to isolate the magnetization of individual grain assemblages, we find that only Fe‐sulfides carry a coherent magnetization. Combined with rock magnetic analyses, we conclude that Allende carries a magnetization acquired during parent body chemical alteration at ~3.0–4.2 My after calcium aluminum‐rich inclusions in an >40 µT magnetic field. This early age strongly favors a magnetic field of nebular origin instead of dynamo or solar wind alternatives. When compared to other paleomagnetic data from meteorites, this strong intensity supports a central role for magnetic instabilities in disk accretion and the presence of temporal variations or spatial heterogeneities in the disk, such as ring and gap structures.
Nearshore Hurricane Intensity Change and Post‐Landfall Dissipation Along The United States Gulf and East Coasts
Authors: Zhu Yi‐Jie , Collins Jennifer M. , Klotzbach Philip J. 
Published: August 2021

AbstractIntensification and dissipation of a hurricane before and after landfall, respectively, are crucial for coastal and inland risk potential. This study examines the relationship between intensity change prior to landfall and post‐landfall dissipation. The relative difference of 24 h accumulated cyclone energy generated before and after landfall is defined as the landfall dissipation rate (LFDR). This study focuses on the continental United States and shows that the 24 h hurricane LFDR is significantly negatively related to the 24 h intensity change before landfall. This implies hurricanes undergoing rapid intensification before landfall weaken at a slower rate after landfall. The decay rate is also positively correlated with landfall intensity but is less certain for Category 4–5 hurricanes (>112 kt). The relationship between near‐shore wind change and post‐landfall decay is not equally distributed along the U.S. coast, with pre‐landfall intensification more common along the Gulf Coast and a LFDR that varies.
Superposed Epoch Analysis of Nighttime Magnetic Perturbation Events Observed in Arctic Canada
Authors: Engebretson Mark J. , Ahmed Lidiya Y. , Pilipenko Viacheslav A. , Steinmetz Erik S. , Moldwin Mark B. , Connors Martin G. , Boteler David H. , Weygand James M. , Coyle Shane , Ohtani Shin , Gjerloev Jesper , Russell Christopher T. 
Published: August 2021

AbstractRapid changes of magnetic fields associated with nighttime magnetic perturbation events (MPEs) with amplitudes |ΔB| of hundreds of nT and 5–10 min duration can induce geomagnetically induced currents (GICs) that can harm technological systems. Here we present superposed epoch analyses of large nighttime MPEs (|dB/dt| ≥ 6 nT/s) observed during 2015 and 2017 at five stations in Arctic Canada ranging from 64.7° to 75.2° in corrected geomagnetic latitude (MLAT) as functions of the interplanetary magnetic field (IMF), solar wind dynamic pressure, density, and velocity, and the SML, SMU, and SYM/H geomagnetic activity indices. Analyses were produced for premidnight and postmidnight events and for three ranges of time after the most recent substorm onset: (a) 0–30 min, (b) 30–60 min, and (c) >60 min. Of the solar wind and IMF parameters studied, only the IMF Bz component showed any consistent temporal variations prior to MPEs: a 1–2 h wide 1–3 nT negative minimum at all stations beginning ∼30–80 min before premidnight MPEs, and minima that were less consistent but often deeper before postmidnight MPEs. Median, 25th, and 75th percentile SuperMAG auroral indices SML (SMU) showed drops (rises) before pre‐ and post‐midnight type A MPEs, but most of the MPEs in categories B and C did not coincide with large‐scale peaks in ionospheric electrojets. Median SYM/H indices were flat near −30 nT for premidnight events and showed no consistent temporal association with any MPE events. More disturbed values of IMF Bz, Psw, Nsw, SML, SMU, and SYM/H appeared postmidnight than premidnight.
UV-LED projection photolithography for high-resolution functional photonic components
Authors: Zheng Lei , Zywietz Urs , Birr Tobias , Duderstadt Martin , Overmeyer Ludger , Roth Bernhard , Reinhardt Carsten 
Published: August 2021

AbstractThe advancement of micro- and nanostructuring techniques in optics is driven by the demand for continuous miniaturization and the high geometrical accuracy of photonic devices and integrated systems. Here, UV-LED projection photolithography is demonstrated as a simple and low-cost approach for rapid generation of two-dimensional optical micro- and nanostructures with high resolution and accuracy using standard optics only. The developed system enables the projection of structure patterns onto a substrate with 1000-fold demagnification. Photonic devices, e.g., waveguides and microring resonators, on rigid or flexible substrates with varied geometrical complexity and overall structure dimensions from the nanometer to centimeter scale were successfully prepared. In particular, high-resolution gratings with feature sizes down to 150 nm and periods as small as 400 nm were realized for the first time by this approach. Waveguides made of doped laser active materials were fabricated, and their spontaneous emission was detected. The demonstrated superior performance of the developed approach may find wide applications in photonics, plasmonics, and optical materials science, among others.
Monolithic integration of nanorod arrays on microfluidic chips for fast and sensitive one-step immunoassays
Authors: Wang Ye , Zhao Jiongdong , Zhu Yu , Dong Shurong , Liu Yang , Sun Yijun , Qian Liling , Yang Wenting , Cao Zhen 
Published: August 2021

AbstractHere, we present integrated nanorod arrays on microfluidic chips for fast and sensitive flow-through immunoassays of physiologically relevant macromolecules. Dense arrays of Au nanorods are easily fabricated through one-step oblique angle deposition, which eliminates the requirement of advanced lithography methods. We report the utility of this plasmonic structure to improve the detection limit of the cardiac troponin I (cTnI) assay by over 6 × 105-fold, reaching down to 33.9 fg mL−1 (~1.4 fM), compared with an identical assay on glass substrates. Through monolithic integration with microfluidic elements, the device enables a flow-through assay for quantitative detection of cTnI in the serum with a detection sensitivity of 6.9 pg mL−1 (~0.3 pM) in <6 min, which was 4000 times lower than conventional glass devices. This ultrasensitive detection arises from the large surface area for antibody conjugation and metal-enhanced fluorescent signals through plasmonic nanostructures. Moreover, due to the parallel arrangement of flow paths, simultaneous detection of multiple cancer biomarkers, including prostate-specific antigen and carcinoembryonic antigen, has been fulfilled with increased signal-to-background ratios. Given the high performance of this assay, together with its simple fabrication process that is compatible with standard mass manufacturing techniques, we expect that the prepared integrated nanorod device can bring on-site point-of-care diagnosis closer to reality.
SARS-CoV-2 disease severity and transmission efficiency is increased for airborne compared to fomite exposure in Syrian hamsters
Authors: Port Julia R. , Yinda Claude Kwe , Owusu Irene Offei , Holbrook Myndi , Fischer Robert , Bushmaker Trenton , Avanzato Victoria A. , Schulz Jonathan E. , Martens Craig , van Doremalen Neeltje , Clancy Chad S. , Munster Vincent J. 
Published: August 2021

AbstractTransmission of SARS-CoV-2 is driven by contact, fomite, and airborne transmission. The relative contribution of different transmission routes remains subject to debate. Here, we show Syrian hamsters are susceptible to SARS-CoV-2 infection through intranasal, aerosol and fomite exposure. Different routes of exposure present with distinct disease manifestations. Intranasal and aerosol inoculation causes severe respiratory pathology, higher virus loads and increased weight loss. In contrast, fomite exposure leads to milder disease manifestation characterized by an anti-inflammatory immune state and delayed shedding pattern. Whereas the overall magnitude of respiratory virus shedding is not linked to disease severity, the onset of shedding is. Early shedding is linked to an increase in disease severity. Airborne transmission is more efficient than fomite transmission and dependent on the direction of the airflow. Carefully characterized SARS-CoV-2 transmission models will be crucial to assess potential changes in transmission and pathogenic potential in the light of the ongoing SARS-CoV-2 evolution.