bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exome sequencing of child–parent trios with bladder exstrophy: Findings in 26 children
Authors: Pitsava Georgia , Feldkamp Marcia L. , Pankratz Nathan , Lane John , Kay Denise M. , Conway Kristin M. , Shaw Gary M. , Reefhuis Jennita , Jenkins Mary M. , Almli Lynn M. , Olshan Andrew F. , Pangilinan Faith , Brody Lawrence C. , Sicko Robert J. , Hobbs Charlotte A. , Bamshad Mike , McGoldrick Daniel , Nickerson Deborah A. , Finnell Richard H. , Mullikin James , Romitti Paul A. , Mills James L. ,   University of Washington Center for Mendelian Genomics, NISC Comparative Sequencing Program and the National Birth Defects Prevention Study
Published: August 2021

AbstractBladder exstrophy (BE) is a rare, lower ventral midline defect with the bladder and part of the urethra exposed. The etiology of BE is unknown but thought to be influenced by genetic variation with more recent studies suggesting a role for rare variants. As such, we conducted paired‐end exome sequencing in 26 child/mother/father trios. Three children had rare (allele frequency ≤ 0.0001 in several public databases) inherited variants in TSPAN4, one with a loss‐of‐function variant and two with missense variants. Two children had loss‐of‐function variants in TUBE1. Four children had rare missense or nonsense variants (one per child) in WNT3, CRKL, MYH9, or LZTR1, genes previously associated with BE. We detected 17 de novo missense variants in 13 children and three de novo loss‐of‐function variants (AKR1C2, PRRX1, PPM1D) in three children (one per child). We also detected rare compound heterozygous loss‐of‐function variants in PLCH2 and CLEC4M and rare inherited missense or loss‐of‐function variants in additional genes applying autosomal recessive (three genes) and X‐linked recessive inheritance models (13 genes). Variants in two genes identified may implicate disruption in cell migration (TUBE1) and adhesion (TSPAN4) processes, mechanisms proposed for BE, and provide additional evidence for rare variants in the development of this defect.
Connecting primate gesture to the evolutionary roots of language: A systematic review
Authors: Rodrigues Evelina D. , Santos António J. , Veppo Flávia , Pereira Joana , Hobaiter Catherine 
Published: August 2021

AbstractComparative psychology provides important contributions to our understanding of the origins of human language. The presence of common features in human and nonhuman primate communication can be used to suggest the evolutionary trajectories of potential precursors to language. However, to do so effectively, our findings must be comparable across diverse species. This systematic review describes the current landscape of data available from studies of gestural communication in human and nonhuman primates that make an explicit connection to language evolution. We found a similar number of studies on human and nonhuman primates, but that very few studies included data from more than one species. As a result, evolutionary inferences remain restricted to comparison across studies. We identify areas of focus, bias, and apparent gaps within the field. Different domains have been studied in human and nonhuman primates, with relatively few nonhuman primate studies of ontogeny and relatively few human studies of gesture form. Diversity in focus, methods, and socio‐ecological context fill important gaps and provide nuanced understanding, but only where the source of any difference between studies is transparent. Many studies provide some definition for their use of gesture; but definitions of gesture, and in particular, criteria for intentional use, are absent in the majority of human studies. We find systematic differences between human and nonhuman primate studies in the research scope, incorporation of other modalities, research setting, and study design. We highlight eight particular areas in a call to action through which we can strengthen our ability to investigate gestural communication's contribution within the evolutionary roots of human language.
Cryotherapy for treatment of chronic rhinitis: 3‐month outcomes of a randomized, sham‐controlled trial
Authors: Del Signore Anthony G. , Greene Joshua B. , Russell Joseph L. , Yen David M. , O'Malley Ellen M. , Schlosser Rodney J. 
Published: August 2021

AbstractBackgroundThe purpose of this study was to test whether cryotherapy is superior to a sham procedure for reducing symptoms of chronic rhinitis.MethodsThis study was a prospective, multicenter, 1:1 randomized, sham‐controlled, patient‐blinded trial. The predetermined sample size was 61 participants per arm. Adults with moderate/severe symptoms of chronic rhinitis who were candidates for cryotherapy under local anesthesia were enrolled. Participants were required to have minimum reflective Total Nasal Symptom Scores (rTNSSs) of 4 for total, 2 for rhinorrhea, and 1 for nasal congestion. Follow‐up visits occurred at 30 and 90 days postprocedure. Patient‐reported outcome measures included the rTNSS, standardized Rhinoconjunctivitis Quality of Life Questionnaire [RQLQ(S)], and Nasal Obstruction Symptom Evaluation (NOSE) questionnaires. Adverse events were also recorded. The primary endpoint was the comparison between the treatment and sham arms for the percentage of responders at 90 days. Responders were defined as participants with a 30% or greater reduction in rTNSS relative to baseline.ResultsTwelve US investigational centers enrolled 133 participants. The primary endpoint analysis included 127 participants (64 active, 63 sham) with 90‐day results. The treatment arm was superior at the 90‐day follow‐up with 73.4% (47 of 64) responders compared with 36.5% (23 of 63) in the sham arm (p < 0.001). There were greater improvements in the rTNSS, RQLQ(S), and NOSE scores for the active arm over the sham arm at the 90‐day follow‐up (p < 0.001). One serious procedure‐related adverse event of anxiety/panic attack was reported.ConclusionCryotherapy is superior to a sham procedure for improving chronic rhinitis symptoms and patient quality of life.
Double‐Twisted Spectroscopy with Delocalized Atoms
Authors: Ivanov Igor P. 
Published: August 2021

AbstractInteraction of atoms with twisted light is the subject of intense experimental and theoretical investigation. In almost all studies, the atom is viewed as a localized probe of the twisted light field. However, as argued in this paper, conceptually novel effects will arise if light‐atom interaction is studied in the double‐twisted regime with delocalized atoms, that is, either via twisted light absorption by atom vortex beam, or via two‐twisted‐photon spectroscopy of atoms in a non‐vortex but delocalized state. Even for monochromatic twisted photons and for an infinitely narrow line, absorption will occur over a finite range of detuning. Inside this range, a rapidly varying absorption probability is predicted, revealing interference fringes induced by two distinct paths leading to the same final state. The number, location, height, and contrast of these fringes can give additional information on the excitation process which would not be accessible in usual spectroscopic settings. Visibility of the predicted effects will be enhanced at the future Gamma factory thanks to the large momenta of ions.
Rhodium(I) Complexes Bearing an Aryl‐Substituted 1,3,5‐Hexatriene Chain: Catalysts for Living Polymerization of Phenylacetylene and Potential Helical Chirality of 1,3,5‐Hexatrienes
Authors: Sakamoto Shiori , Taniguchi Tsuyoshi , Sakata Yoko , Akine Shigehisa , Nishimura Tatsuya , Maeda Katsuhiro 
Published: August 2021

AbstractUnique bench‐stable rhodium(I) complexes bearing an aryl‐substituted 1,3,5‐hexatriene chain have been synthesized by reactions of (bicyclo[2.2.1]hepta‐2,5‐diene)rhodium(I) chloride dimer ([Rh(nbd)Cl]2) with aryl boronic acids and diphenylacetylenes in the presence of a 50 % aqueous solution of KOH. X‐ray crystallographic analysis of the isolated complexes indicated a square‐planar structure stabilized by a strong interaction with one of the aryl groups on the 1,3,5‐hexatriene chain, which has a helical structure. The helical chirality of the isolated rhodium complexes was confirmed to be sufficiently stable to be resolved into enantiomers by HPLC on a chiral stationary phase at room temperature. It was confirmed that the isolated rhodium complexes functioned as initiators for living polymerization of phenylacetylene to give cis‐stereoregular poly(phenylacetylene) with a well‐controlled molecular weight.
Ein MOF‐basierter CuxOyCz‐Katalysator für die elektrochemische CO2‐Reduktion und die Auswirkungen der lokalen pH‐Änderung
Authors: Sikdar Nivedita , Junqueira João R. C. , Dieckhöfer Stefan , Quast Thomas , Braun Michael , Song Yanfang , Aiyappa Harshitha B. , Seisel Sabine , Weidner Jonas , Öhl Denis , Andronescu Corina , Schuhmann Wolfgang 
Published: August 2021

AbstractDie Entwicklung hocheffizienter und selektiver Elektrokatalysatoren für die CO2‐Reduktionsreaktion zur Herstellung von Chemikalien mit hohem Mehrwert wird intensiv untersucht. Wir berichten über eine Reihe von CuxOyCz nanostrukturierten Elektrokatalysatoren, die von einem MOF auf Cu‐Basis als poröses selbstopferndes Templat abgeleitet sind. Die Mischung der Katalysatoren mit Polytetrafluorethylen (PTFE) auf Gasdiffusionselektroden (GDEs) unterdrückte die konkurrierende Wasserstoffentwicklungsreaktion. Mit 25 bis 50 Gew.‐% teflonisierter GDEs wurde bei einer Stromdichte von 80 mA cm−2 eine Faradayeffizienz von ≈54 % für C2+‐Produkte erzielt. Die lokale OH−‐Ionenaktivität der PTFE‐modifizierten GDEs wurde durch die Positionierung einer Pt‐Nanoelektrode in unmittelbarer Nähe der GDE bestimmt. Unabhängig von der PTFE‐Menge wurde ein erheblicher Anstieg des OH−/H2O‐Aktivitätsverhältnisses aufgrund der lokal erzeugten OH−‐Ionen bei steigenden Stromdichten festgestellt.
A LaFeO3 supported natural‐clay‐mineral catalyst for efficient pyrolysis of polypropylene plastic material
Authors: Nguyen Linh T. Tr. , Poinern Gérrard Eddy Jai , Le Hanh T. , Nguyen Tien A. , Tran Chien M. , Jiang Zhong‐Tao 
Published: August 2021

AbstractThe pyrolysis and catalytic reforming process of waste plastics are the best pathways to handle vast amounts of waste plastics as they can convert these waste polymers into sustainable products. This study aims to incorporate a natural‐clay‐mineral (NCM) with LaFeO3 nanoparticles, with the LaFeO3/NCM catalyst in the pyrolysis of polypropylene (PP) being used as an example of plastic waste. The decomposition of PP with and without catalyst has been theoretically studied using thermogravimetry (TG) and differential scanning calorimetry (DSC) measurements under atmospheric pressure and nitrogen atmosphere. The TG/DSC results show that (i) the required temperature for pyrolysis of PP with or without catalyst in a practical system ranges from 460°C to 480°C; (ii) the amount of coke produced on the surface of the NCM or LaFeO3 is about 2 wt.% compared with the initial plastic levels; (iii) with the catalyst, PP not only goes through the phase transitions of solid to liquid to gas but also decomposition and combination processes between components from the hydrocarbon chain scission of PP. Gas chromatography–mass spectrometry (GC–MS) results show significant differences in the fuel oil recovered from the pyrolysis and catalytic reforming process. In the presence of the catalyst, cracking components consist of 49.3% alkenes (branched‐chain alkenes, cyclo‐alkenes, and alkenes) and 34.4% alkanes, while without the catalyst, branched‐chain alkenes were up to 90.2%. Repeated pyrolysis and GC–MS investigations demonstrated the reusability of the LaFeO3/NCM catalyst, which is promising for its recycling and the efficient pyrolysis of PP.
The modified polythiophene‐Cu NPs composites for Pb(II) ions removal from aqueous solution
Authors: Karegar Mohsen , Khodaei Mohammad Mehdi 
Published: August 2021

AbstractThe present work describes the use of chemically modified polythiophene with copper nanoparticles and polyvinylpyrolidine‐sulfonic acid (PTh‐PVP‐SA‐Cu) as an adsorbent for the removal of Pb(II) ions from aqueous solution. The synthesized composite, PTh‐PVP‐SACu, was characterized by different techniques including Fourier‐transform infrared spectrometer, scanning electron microscopy, energy dispersive X‐ray spectroscopy (EDX), transmission electron microscopy, X‐ray powder diffraction, thermogravimetric analysis (TGA), and differential scanning calorimetry. This nanocomposite has good conductivity and thermal stability due to the presence of copper nanoparticles. The acidic doping agent, polyvinylpyrolidine‐sulfonic acid, can act as the surfactant and improves the polymerization of thiophene in the aqueous medium. The conductivity of PTh was 0.54 S/cm, while the conductivities of PTh‐Cu with 10 and 20 wt% of PVP‐SA under the same reaction conditions were 2.3 and 2.7 S/cm, respectively. The influence of pH, adsorbent dosage, temperature, contact time, and concentration on the removal of Pb(II) ions was evaluated. The optimum conditions for the removal of Pb(II) ions were 25°C with the adsorbent dosage of 3 g.L−1 at pH = 7. The adsorption capacity was obtained to be 111 mg. g−1. The obtained equilibrium data for PTh‐PVP‐SA‐Cu was fitted well by Langmuir isotherm model indicating that the adsorption process was monolayer adsorption and distribution of adsorption sites on the surface of PTh‐PVP‐SA‐Cu was homogeneous. The maximum monolayer capacity obtained from the Langmuir isotherm was 121.9 mg. g−1 for Pb(II) ions at 45°C. The values of Gibbs free energy (ΔG), entropy change (ΔS) and enthalpy change (ΔH) indicated the feasibility, spontaneity and the endothermic nature of the adsorption process, respectively. The kinetic process followed the pseudo‐second‐order kinetic model. The recyclability studies revealed that PTh‐PVP‐SA‐Cu could be reused for three consecutive cycles.
Lipophilic rheology modifier and its application in oil‐based drilling fluids
Authors: Zhou Yan , Pu Xiaolin 
Published: August 2021

AbstractControl of rheological behavior plays an important role in the process of wellbore construction and ensure the success of drilling operation. This paper reports for the first time the use of poly‐amide (SMN) and poly‐ester (SMO) as potential rheology modifiers. Fourier transform infrared (FTIR) spectroscopy, nuclear magnetic resonance, and thermogravimetric analysis have been carried out to confirm the chemical structures and properties of SMN and SMO. The results from environmental scanning electron microscope (ESEM) illustrated that SMN and SMO are lamellar structures formed by the stacking or interpenetrating of thin sheets. The atomic force microscope test results show that the network structure is formed after dissolving rheology modifier in diesel oil. Combining with the rheology and suspension measurements, it can be determined that the addition of rheology modifier exhibited obvious influence on the viscosity, thixotropy, and settlement factor of W/O emulsion. The rheology control properties and suspension stability between two rheology modifiers and traditional rheology modifier organoclay were compared. After hot rolling at 180°C, the base mud containing organoclay exhibited excellent suspension stability, but the fluid had completely lost fluidity and consolidated into a block. For SMN and SMO addition into the base formula, the rheological parameters of base mud changed moderately and the settlement of barites was not observed after standing for 24 h.
Isolated iron/polyether sulfone catalytic membranes for rapid phenol removal
Authors: Huang Lilan , Wang Shaofei , Chen Haimei , Hou Xiaoyang , Zhang Han , Pan Jian , Zhang Yuzhong 
Published: August 2021

AbstractPhenolic waster has a pervasive problem afflicting people throughout the word due to negative impacts for ecosystems and humans. Herein, isolated iron/polyethersulfone (4A‐Fe/PES) mixed‐matrix membrane as a catalytic non‐permselective membrane reactor is developed for rapid reduction of phenol in continuous flow‐through reaction. The forced flow of the reactants through the membrane intensifies the contact between reactants and immobilized catalysts, allowing for high catalytic activity with negligible mass transport resistances. In the presence of H2O2, the 4A‐Fe/PES catalytic membrane can remove 99.9 ± 1.6% phenol after 6 min at pH 2 with a catalyst/phenol mass ratio of 1/3. The catalytic membranes show much higher performances than 4A‐Fe particles even under neutral or alkaline conditions. In particular, at pH 9, the catalytic membrane exhibits a phenol degradation rate of 92.5 ± 3.4% after 12 h. This strategy provides guidance to the design of high‐performance catalytic membranes for efficient removal of phenolic pollutants.
Kombucha SCOBY Waste as a Catalyst Support
Authors: Tang Karen Yuanting , Heng Jerry Zhi Xiong , Lin Ming , Li Zibiao , Ye Enyi , Loh Xian Jun 
Published: August 2021

AbstractIt is established that food waste can be repurposed to extend its lifecycle and decrease its carbon footprint. In this work, SCOBY (symbiotic culture of bacteria and yeast) waste from kombucha tea production has been repurposed as a catalyst support. Copper nanoparticles (Cu NPs) have been embedded in a piece of treated SCOBY via an in‐situ method which enabled the catalyst, inCu/t‐SCOBY, to be easily recycled. In addition, inCu/t‐SCOBY catalyzed the full reduction of 4‐nitrophenol in an excess of sodium borohydride (NaBH4) within 20 minutes. After 6 additional catalytic cycles, the catalyst maintained up to 50% of its performance in the first cycle. Characterization of the catalyst has also been done to understand the mechanism of action and interactions occurring between t‐SCOBY and Cu NPs. The results of this work clearly present a proof‐of‐concept in utilizing porous wastes materials such as SCOBY as catalyst supports, allowing metallic NPs to be efficacious and practical heterogenous catalysts.
Ecological momentary assessment of emotional processing: An exploratory analysis comparing daily life and a psychotherapy analogue session
Authors: Beuchat Hélène , Grandjean Loris , Despland Jean‐Nicolas , Pascual‐Leone Antonio , Gholam Mehdi , Swendsen Joel , Kramer Ueli 
Published: August 2021

AbstractBackgroundEmotional processing has been studied in psychotherapy as a state‐dependent, sequential process of change. So far, no studies have applied this conceptualisation of emotional processing to the assessments of emotion in daily life. This is particularly important in the light of the pertinence of day‐by‐day fluctuations of emotions for understanding mental health and for monitoring the impact of prevention and psychotherapy programmes. This study examined the internal and ecological validity of a state‐dependent conceptualisation of emotional processing in daily life, in comparison with an experiential‐psychodynamic psychotherapy analogue session.MethodsIn total, N = 42 university students participated in an experiential‐psychodynamic session, completed symptom measures and responded to a one‐week period of ecological momentary assessment (EMA) using a smartphone. Emotional processing in the session was assessed using the valid observer‐rated measure Classification of Affective Meaning States (CAMS), and emotional responses in daily life were assessed using newly developed theory‐consistent items self‐rated via an interactive smartphone program.ResultsInternal validity was generally satisfactory across the subscales used in EMA. Correspondence between EMA and in‐session emotional processing was generally low, but specific relationships were found between self‐rated fear, rejecting anger, hurt/grief or loneliness and the observer‐rated productive emotions in the psychotherapy analogue session. Relationships between maladaptive emotional processing and intensity in symptoms were found.ConclusionsThis is the first study to have examined the validity of a state‐dependent conception of emotional processing in daily life, in direct comparison with a psychological session. We recommend using this assessment schedule to develop or complement integrative prevention or intervention programmes.
Leading with gratitude, authenticity makes challenging times more manageable
Authors: McCarthy Claudine 
Published: August 2021

During the pandemic, Matt Ennis, Director of Athletics and Student Activities at the State College of Florida, Manatee‐Sarasota, set out to lead with gratitude and optimism while also being as upfront as possible with students about what they could expect. “We continually shared our gratitude for the opportunity we were being provided. Being authentic was more important this last year than ever. We took on the mantra of persevering in the fall so we can chase championships in the spring,” said Ennis, who has worked in college athletics for 17 years. He's also a recipient of the 2020‐21 NACDA AD of the Year Awards for the Junior/Community Colleges division.
Implications of concomitant obstructive or restrictive pulmonary diseases on functional and clinical results after MitraClip
Authors: Schneider Leonhard Moritz , Nicoleta Nita , Schepperle Niklas , Paukovitsch Michael , Haide Uli , Feuerabendt Sieglinde , Keßler Mirjam , Rottbauer Wolfgang , Markovic Sinisa 
Published: August 2021

AbstractObjectivesWe investigated the impact of underlying pulmonary limitations (PL) on symptoms and clinical outcomes after transcatheter mitral valve repair (TMVr).BackgroundPatients with pulmonary disease and patients with symptomatic mitral regurgitation (MR) suffer common symptoms like dyspnea and reduced exercise capacity.MethodsDatasets from the TMVr Ulm registry were retrospectively analyzed by a blinded specialist in pneumology. Patients were dichotomized according to an unambiguous manifestation of concomitant pulmonary disease in a PL‐group and a non‐PL‐group and were analyzed regarding baseline characteristics and clinical follow‐up.ResultsOverall, 483 patients were included in the study of which 32.3% (n = 156) showed an underlying pulmonary disease. Patients in the PL‐group were similar to patients in the non‐PL‐group, including Euro SCORE II (8.2 vs. 8.4, p = 0.39), New York Heart Association (NYHA) classification (3.2 ± 0.7 in both groups, p = 0.65) and the incidence of moderate‐to‐severe or severe MR after TMVr (5.8 vs. 8.3%, p = 0.32). Equal and significant symptom relief after TMVr was experienced in both cohorts according to NYHA functional class (2.24 ± 0.84 vs. 2.24 ± 0.86, p = 0.93) and rate of hospitalization during 2 years of follow‐up decreased comparably from 61.1 to 19.3%. However, all‐cause mortality for 2 year follow‐up was significantly higher in the PL‐group compared to the non‐PL‐group (31.4 vs. 21.4%, p = 0.018).ConclusionIn patients with MR and concomitant pulmonary disorders, a significant increase of exercise capacity and a significant decrease of rehospitalization rate were observed after TMVr. Nevertheless, all‐cause mortality remains significantly increased within a follow‐up period of 2 years compared to patients without pulmonary disorders.
A case of mistaken arrhythmogenic identity during pregnancy
Authors: Asher Clint , Thomas Tessa , Rinaldi Christopher A. , Carr‐White Gerry 
Published: August 2021

AbstractAtypical LVOT ectopy can present with an RVOT morphology on ECG and differentiation to reveal this focus is in favor of benign idiopathic ventricular ectopy over an arrhythmogenic cardiomyopathy.
Zukunftssicher in die Industrie 4.0
Authors: Hermann Alexander 
Published: August 2021

AbstractCerabar und Deltabar ebnen den Weg in die Industrie 4.0 und bringen smarte Prozesssicherheit für Anlagenbetreiber. Die sichere kabellose Kommunikation eröffnet viele Möglichkeiten, die Prozesse zu überwachen, zu optimieren und auch die Sensoren selbst zu monitoren.
Sicher, schnell und vielseitig
Authors: Krause Peter 
Published: August 2021

AbstractCPC‐Schnellkupplungen sind einfach zu bedienende Schlauchverbinder für Flüssigkeiten und für Gase. Standard‐Schnellkupplungen, High‐Flow‐Schnellkupplungen, Non‐Spill‐Schnellkupplungen, Messing‐verchromte Schnellkupplungen und Mehrfach‐Schnellkupplungen de