bluuebunny/crossref_metadata_2025_split huggingface dataset:
#LadiesWeGotYou: Stances of moral–political alignment in the formation of group Identity on Facebook
Authors: Zentz Lauren 
Published: June 2021

AbstractIn this article I focus on how leaders of a progressive activist group in Houston, Texas interacted with each other on Facebook, collaboratively formulating a group identity exemplified through a set of stances that I callmoral political stances. Through microlevel examination of two postcomment sequences, I examine exactly how these participants wrote themselves into being as a singular and unified group of politically and morally motivated actors. As the group collectively relied upon and supported each other's assumptions of moral political stances, they actively constructed their own group identity, in front‐ and backstage spaces, as the leaders and organizers of the structure and moral political framework of their activist organization. This collaborative construction, I argue, was further meant to influence and set the moral guidelines for the larger group identities of their organization and to portray this identity to groups of their Facebook Friends beyond these circles.
Farm Dinner Theater: Testing an innovative health and safety intervention among older farmers and their families
Authors: McCallum Debra M. , Reed Deborah B. , Claunch Deborah T. , Davis Cali M. , Conaway Michael B. 
Published: June 2021

AbstractPurposeThe effectiveness of a novel intervention for increasing health and safety behaviors of older farmers was tested. Blending didactic and readers’ theater techniques, Farm Dinner Theater (FDT) engages farmers in discussions of health and safety in a nonthreatening social atmosphere supportive of potential changes.MethodsThrough community collaborations, farmers 45 years and older were recruited in 8 communities for the FDT. For each site, 3 scripts were prepared highlighting health and safety issues especially relevant for older farmers. The brief plays were performed in a dinner theater format, with group discussion following each play. Printed educational packets (EPs) addressing the same topics were mailed to comparison groups of participants in 9 communities. In telephone interviews conducted 2 weeks and 2 months later, 870 participants (553 FDT and 317 EP) reported health and safety‐related changes they had made in their farm operations.FindingsFDT participants were more likely than EP participants to report having made any changes and reported making more changes on both the 2‐week and 2‐month follow‐up assessments. This outcome occurred when analyzing all farms and when considering only farms with at least 1 participant who spent 10 or more hours per week farming.ConclusionsFDT is a fun, relaxing intervention; it is acceptable to farming communities; and it is more effective in producing health and safety‐related changes than the common approach of providing printed materials. FDT not only had a greater impact than EP, but it has the potential to reach larger audiences due to its greater appeal.
Spatial and seasonal variations in surface water temperature and salinity in the Mexico‐Belize riverine estuary: Possible comfort conditions for manatees?
Authors: Callejas‐Jiménez Mariana E. , Alcérreca‐Huerta Juan Carlos , Morales‐Vela Benjamin , Carrillo Laura 
Published: June 2021

AbstractThe Mexican Caribbean and Belize are home to one of the largest populations of Caribbean manatees (Trichechus manatus manatus). However, the transboundary Hondo River estuary is less examined compared to the surrounding protected areas. This paper provides a quantitative description of the spatial and temporal variability in abiotic factors and manatee distribution throughout the Hondo River estuary, with monthly field measurements during 2018–2019. Simultaneously, visual observations and side‐scan sonar detection were implemented, with 84 manatee sightings reported (calves 11.9%, noncalves 88.1%). Heatmap and frequency analyses showed that most manatee sightings occurred at the riverine estuary limit, the confluences between the river and the bay into which it flows. The surface water temperature and salinity ranged 28°C ≤ T ≤ 32°C and 0.5 PSU ≤ S ≤ 4.5 PSU for ~72% of the manatees identified, potentially describing locally preferred conditions for manatees. During the regional mid‐summer drought, higher temperature (31.5°C), salinity (18 PSU), and estuary extent (17.6 km) were recorded, including the maximum peak of manatee sightings (~31%). The roles of these abiotic factors are discussed as tentative environmental comfort conditions for manatees that could reduce their energy and maintenance costs. The identification of preferred conditions could broaden perspectives on how manatees interact with their habitats.
A poplar B‐box protein PtrBBX23 modulates the accumulation of anthocyanins and proanthocyanidins in response to high light
Authors: Li Chaofeng , Pei Jinli , Yan Xin , Cui Xin , Tsuruta Momi , Liu Ying , Lian Chunlan 
Published: June 2021

AbstractFlavonoids, which modulate plant resistance to various stresses, can be induced by high light. B‐box (BBX) transcription factors (TFs) play crucial roles in the transcriptional regulation of flavonoids biosynthesis, but limited information is available on the association of BBX proteins with high light. We present a detailed overview of 45 Populus trichocarpa BBX TFs. Phylogenetic relationships, gene structure, tissue‐specific expression patterns and expression profiles were determined under 10 stress or phytohormone treatments to screen candidate BBX proteins associated with the flavonoid pathway. Sixteen candidate genes were identified, of which five were expressed predominantly in young leaves and roots, and BBX23 showed the most distinct response to high light. Overexpression of BBX23 in poplar activated expression of MYB TFs and structural genes in the flavonoid pathway, thereby promoting the accumulation of proanthocyanidins and anthocyanins. CRISPR/Cas9‐generated knockout of BBX23 resulted in the opposite trend. Furthermore, the phenotype induced by BBX23 overexpression was enhanced under exposure to high light. BBX23 was capable of binding directly to the promoters of proanthocyanidin‐ and anthocyanin‐specific genes, and its interaction with HY5 enhanced activation activity. We identified novel regulators of flavonoid biosynthesis in poplar, thereby enhancing our general understanding of the transcriptional regulatory mechanisms involved.
Is prolonged monitoring necessary? An updated approach to infantile hemangioma treatment with oral propranolol
Authors: Johansen Maija Liv , Mahendran Geetha , Lawley Leslie P. 
Published: June 2021

AbstractBackground/ObjectivesInfantile hemangiomas (IH) are the most common soft‐tissue tumors in childhood, occurring in up to 1 in 10 infants. Oral propranolol has been well established as the first‐line treatment of complicated hemangiomas; however, variability in the administration protocol remains. We sought to evaluate our current propranolol treatment protocols to determine if the level of monitoring and follow‐up predicts immediate or future adverse events by comparing one in‐person visit vs two in‐person visits versus teledermatology for treatment initiation and dose escalation.MethodsWe analyzed retrospective data on 279 patients diagnosed with IH and treated with oral propranolol on an in‐person or virtual telemedicine outpatient basis from January 01, 2015 through May 31, 2020. Data were collected via chart review on all aspects of patient demographics, treatment indication, treatment initiation, adverse events, and follow‐up visits.ResultsTwo monitoring visits (Protocol 1) versus one (Protocol 2) was not associated with decreased adverse outcomes (P = .255). The odds of having an adverse event in Protocol 1 compared to Protocol 2 was insignificant (OR: 0.64; CI: 0.30‐1.38). The most frequently reported adverse event among patients in both protocols was sleep disturbance. However, it did not vary significantly among the groups (P = .980, OR: 0.98, CI: 0.35‐2.69).ConclusionProlonged in‐office monitoring of propranolol initiation and dose escalation (Protocol 1) may not be necessary for the setting of adequate prescreening as it does not predict immediate or future adverse events.
Correlation between the number of viable tumor cells and immune cells in the tumor microenvironment in non‐small cell lung cancer after induction therapy
Authors: Hoshino Hironobu , Aokage Keiju , Miyoshi Tomohiro , Tane Kenta , Kojima Motohiro , Sugano Masato , Kuwata Takeshi , Ochiai Atsushi , Suzuki Kenji , Tsuboi Masahiro , Ishii Genichiro 
Published: June 2021

AbstractThis study aims to determine the correlation between the percent viable tumor cells (%VTC) and the tumor microenvironment in resected non‐small cell lung cancer after induction therapy. We enrolled 72 patients with non‐small cell lung cancer (NSCLC) who received chemoradiotherapy (CRT) or chemotherapy (CT) prior to surgery. The ratio of the area of viable tumor cells to the total tumor area was calculated to obtain the %VTC. We also examined the number of CD4 (+), CD8 (+), CD20 (+) and FOXP3 (+) tumor‐infiltrating lymphocytes (TILs), podoplanin (PDPN) (+) cancer‐associated fibroblasts (CAFs), and CD204 (+) tumor‐associated macrophages (TAMs) by immunohistochemistry (IHC). In the CRT group (n = 37), the tumors had significantly lower %VTC than the CT group (n = 35) (P < 0.001). In both of the CT group and CRT group, the %VTC showed a significant positive correlation with the number of CD204 (+)‐TAMs (P = 0.014 and 0.005, respectively). Only in the CRT group, a higher number of CD204 (+) TAMs was associated with a shorter overall survival (OS) (P = 0.007) and recurrence‐free survival (RFS) (P = 0.015). In the CRT group, the number of CD204 (+) TAMs is associated with %VTC and prognosis, suggesting that these cells may have tumor‐promoting effects on the residual lung cancer in specific microenvironments after CRT.
Socially induced negative affective knowledge modulates early face perception but not gaze cueing of attention
Authors: Matyjek Magdalena , Kroczek Bartłomiej , Senderecka Magdalena 
Published: June 2021

AbstractPrior affective and social knowledge about other individuals has been shown to modulate perception of their faces and gaze‐related attentional processes. However, it remains unclear whether emotionally charged knowledge acquired through interactive social learning also modulates face processing and attentional control. Thus, the aim of this study was to test whether affective knowledge induced through social interactions in a naturalistic exchange game can influence early stages of face processing and attentional shifts in a subsequent gaze‐cueing task. As indicated by self‐reported ratings, the game was successful in inducing valenced affective knowledge towards positive and negative players. In the subsequent task, in which the locations of future targets were cued by the gaze of the game players, we observed enhanced early neural activity (larger amplitude of the P1 component) in response to a photograph of the negative player. This indicates that negative affective knowledge about an individual indeed modulates very early stages of the processing of this individual's face. Our study contributes to the existing literature by providing further evidence for the saliency of interactive social exchange paradigms that are used to induce affective knowledge. Moreover, it extends the previous research by presenting a very early modulation of perception by socially learned affective knowledge. Importantly, it also offers increased ecological validity of the findings due to the use of naturalistic social exchange in the study design.
Ablation of a Solid Material by High Temperature Liquid Jet Impingement: An Application to Corium Jet Impingement on a Sfr Core-Catcher
Authors: Lecoanet Alexandre , Gradeck Michel , Gaus-Liu Xiaoyang , Cron Thomas , Fluhrer Beatrix , Payot Frederic , Journeau Christophe , Rimbert Nicolas 
Published: June 2021

Abstract
This paper deals with ablation of a solid by a high temperature liquid jet. This phenomenon is a key issue to maintain the vessel integrity during the course of a nuclear reactor severe accident with melting of the core. Depending on the course of such an accident, high temperature corium jets might impinge and ablate the vessel material leading to its potential failure. Since Fukushima Daiichi accident, new mitigation measures are under study. As a designed safety feature of a future European SFR, bearing the purpose of quickly draining of the corium out of the core and protecting the reactor vessel against the attack of molten melt, the in-core corium is relocated via discharge tubes to an in-vessel core-catcher has been planned. The core-catcher design to withstand corium jet impingement demands the knowledge of very complex phenomena such as the dynamics of cavity formation and associated heat transfers. Even studied in the past, no complete data are available concerning the variation of jet parameters and solid structure materials. For a deep understanding of this phenomenon, new tests have been performed using both simulant and prototypical jet and core catcher materials. Part of these tests have been done at University of Lorraine using hot liquid water impinging on transparent ice block allowing for the visualizations of the cavity formation. Other tests have been performed in Karlsruhe Institute of Technology using liquid steel impinging on steel block.
Early gastrogastric fistula after Roux-en-Y gastric bypass: successful fistula treatment with self-expandable endoscopic stent
Authors: Süsstrunk Julian , Thumshirn Miriam , Peterli Ralph , Kraljević Marko 
Published: June 2021

A 25-year-old patient underwent laparoscopic Roux-en-Y gastric bypass surgery with an initially uneventful postoperative course. Two weeks postoperatively, the patient presented with acute abdominal pain. CT scan revealed a gastrogastric fistula from the gastric pouch to the gastric remnant. Laparoscopic drainage was performed, and intraoperative endoscopy confirmed a large gastrogastric fistula. Due to intense adhesions between pouch and remnant, a closure by suture of the fistula was not possible. The fistula was initially treated with a fully covered metal stent. After multiple stent migrations despite clip attachment to the mucosa, the stent was changed to a partially covered metal stent. Fistula healing progress was documented every 2 weeks. After 10 weeks of stent treatment, fistula closure was accomplished.In conclusion, early fistula from the gastric pouch to the gastric remnant is a rare complication and can be managed with endoscopic stent placement.
Oxylipin profiles and levels vary by skeletal muscle type, dietary fat and sex in young rats
Authors: Penner Avery L. , Waytt Victoria , Winter Tanja , Leng Shan , Duhamel Todd A. , Aukema Harold M. 
Published: June 2021

Polyunsaturated fatty acids (PUFA)-derived bioactive lipid mediators called oxylipins have been shown to influence muscle growth, inflammation and repair in select muscles. Since individual oxylipins have varying effects and potencies, broad profiling in differing muscle types is required to further understand their overall effects. In addition, diet and sex are key determinants of oxylipin levels. Therefore, to provide comprehensive data on oxylipin profiles in rat soleus (SO), red gastrocnemius (RG), and white gastrocnemius (WG) muscles, female and male weanling Sprague–Dawley rats were provided control or experimental diets enriched in n-3 (ω-3) or n-6 (ω-6) PUFA for 6 weeks. Free oxylipin analysis by HPLC/MS/MS revealed that SO muscle had 25% more oxylipins and 4–13 times greater oxylipin mass than WG muscle. Dietary n-3 PUFA (α-linolenic acid, eicosapentaenoic acid, and docosahexaenoic acid) each increased n-3 oxylipins derived directly from their precursors and several that were not direct precursors, while reducing arachidonic acid derived oxylipins. Dietary linoleic acid had few effects on oxylipins. Oxylipins with a sex effect were higher in females in SO and RG. Oxylipins generally reflected the effects of diet and sex on PUFA, but there were exceptions. These fundamental oxylipin profile data provide groundwork knowledge and context for future research on muscle oxylipin functions. Novelty: Rat SO compared with RG and WG muscles have a higher number and greater mass of oxylipins. Oxylipins generally reflect diet effects on PUFA in all muscles, but there are notable exceptions. Oxylipins in SO and RG are higher in females.
Influence of cropping system and soil type on soil health
Authors: Marshall Carolyn B. , Burton David L. , Heung Brandon , Lynch Derek H. 
Published: June 2021

There has been a continued adaption and application of soil health tests across all regions of the globe; however, there are challenges related to the interpretation of the results of soil health tests developed in one region but applied elsewhere. To determine the factors that are the most important for interpreting soil health tests in Nova Scotia, a soil health database was constructed using soil samples from diverse cropping systems and soil orders in the region. The Comprehensive Assessment of Soil Health, developed at Cornell University in New York, was adapted and combined with other soil health measures. Principal component analysis (PCA), analysis of variance, and a correlation analysis were applied to the dataset to determine if management (i.e., cropping system) or pedogenesis (i.e., soil order) was more important as a driver of soil health test results. It was determined that cropping systems explained more variance in the dataset than soil order. Although total carbon explained the most variation in the PCA, it was highly correlated to other measures of carbon such as permanganate oxidizable carbon and respiration that may be more responsive to management changes. In addition, autoclaved-citrate extractable protein, a test for nitrogen mineralization, was more related to measures of soil carbon than other measures of soil nitrogen availability. The findings of this study provide a foundation for interpreting soil health testing results for this region and will help indicate which cropping systems and soil management practices have the greatest potential for improving soil health.
EVALUATION OF TIBIAL COMPONENT ROTATION IN PAINFUL TOTAL KNEE ARTHROPLASTIES BY MRI ENHANCED WITH METAL ARTIFACT REDUCTION TECHNIQUE
Authors: Elkabbani Mohamed , Osman Amr , Helaly Mohamed , Tarabichi Samih 
Published: June 2021

Background: Tibial component malrotation is one of the commonest causes of pain and stiffness following total knee arthroplasties, however, the assessment of tibial component malrotation on imaging is not clear-cut. The objective of this study was to assess tibial component rotation in cases with pain following total knee replacement using MRI with metal artifact reduction technique. Methods: In 15 consecutive patients presented in our clinic — a high-volume arthroplasty institution — between January 2017 and June 2017 with persistent unexplained moderate to severe pain for at least 6 months following total knee arthroplasties, which were ALL done outside our institution, after exclusion of infection and loosening (tibial or femoral), MRI evaluation of tibial component rotation using metal artifact reduction for orthopedic implants (O-MAR) technique — to improve visualization of soft tissue and bone by reducing artifacts caused by metal implants — was done according to the technique of Berger et al. [Malrotation causing patellofemoral complications after total knee arthroplasty. Clin Orthop Relat Res 144–153, 1998]. Results: Eleven cases showed an internal rotation of tibial components (73.3%), four cases showed a neutral or external rotation of tibial components (26.6%), however, with the presence of abnormal intraarticular fibrous bands in two of them. Conclusions: Two main conclusions are obtained from this study: Firstly, internal rotation of tibial component must be excluded in all cases of persistent pain following total knee replacement. Secondly, magnetic resonance imaging with the newly developed metal artifact reduction techniques is a very useful tool in evaluating cases of unexplained pain following total knee replacement.
Early Onset Age Increased the Risk of Diabetic Retinopathy in Type 2 Diabetes Patients with Duration of 10–20 Years and HbA1C ≥7%: A Hospital-Based Case-Control Study
Authors: Yuan Jing , Zhang Lin , Jia Pu , Xin Zhong , Yang Jin-Kui 
Published: June 2021

Background. The relationship between onset age of diabetes and diabetic retinopathy (DR) is controversy and not concluded. Therefore, this hospital-based case-control study aimed to investigate the influence of diabetes onset age on the development of DR in patients with type 2 diabetes (T2D), independent of diabetic duration and HbA1c levels. Methods. A sample of 780 T2D patients with diabetic duration of 10–20 years and glycated hemoglobin (HbA1c) ≥7% were enrolled in the study. 338 T2D patients with onset age ≤45 years were further selected as cases (early onset) and 79 with onset age ≥ 55 years were chosen as controls (elderly onset). International Clinical Diabetic Retinopathy Disease Severity Scale was applied to estimate the severity of DR. Results. The prevalence of DR and proliferative diabetic retinopathy (PDR) was notably increased in the early onset group. When stratified by duration of diabetes, the impact of younger age on the risk of DR turned to be greatest in patients with diabetic duration ≥15 years (OR = 5.202, 95% CI 2.625–10.310). In groups stratified by HbA1c, the risk of DR was highest in patients with younger onset age and HbA1c ≥ 9% (OR = 3.889, 95% CI 1.852–8.167). Compared with the elderly onset group, the risk of DR (OR = 1.776, 95% CI = 1.326–2.380,

p

< 0.001) and PDR (OR = 1.605, 95% CI = 1.106–2.329,

p

= 0.013) in younger diagnosed patients was increased after multivariable adjustment. Conclusions. Age of onset was an independent risk factor for developing DR and PDR. This suggests that it is urgent to closely monitor and treat the metabolic disorders in younger T2D patients to delay the occurrence and progression of DR.