bluuebunny/crossref_metadata_2025_split huggingface dataset:
Il paesaggio sonoro campano tra contemporaneità e nuove forme di progettualità turistica
Authors: Citarella Germana 
Published: August 2021

Full awareness of landscape occurs when it is holistically perceived. In other words, when there is osmosis between subject and object in terms of our observing, touching, breathing and listening to the same. Contemporaneously, the diminished attention paid to information provided by acoustic perception has had the effect of generating a propensity for looking rather than listening. The contribution intends to illustrate the soundscape of Campania through the tammurriata. It is not just one of the many forms of popular music expression, but the dance contains the focal points of a complex experience of collective participation, resulting in a significant tool for territorial knowledge, capable of promoting alternative forms of tourism and sense of community.
Progettare il silenzio. Una lettura acustica dell’ex villaggio sanatoriale Morelli a Sondalo
Authors: Mocchi Martino 
Published: August 2021

The sanatorium Morelli was built in Sondalo during the fascist era (1932-1940). The strong visual impact of the structure is counterbalanced by a delicate acoustic approach, made necessary by the need to create silent places for supporting medical treatments. The project of “silence” is not only the result of a punitive stance, which simply intends to reduce sound emissions, but above all the effect of a positive attitude, aiming at selecting specific sounds, in accordance with the social and environmental characteristics of place. This produces the sense of participation and identification of the users, generating collective cares and protection. That of Morelli, indeed, is a relevant lesson for the contemporary reflection, with a view to finding good strategies for soundscape design.
I suoni di Mantova come strumenti di interpretazione del paesaggio. Tra turismo sostenibile ed educazione al patrimonio culturale
Authors: Pecorelli Valeria , Zuccoli Franca , Alessandra De Nicola , Squarcina Enrico 
Published: August 2021

This article presents an educational experience in schools held by academics in the UNESCO site of Mantova and Sabbioneta. It is the result of a wider, interdisciplinary study – sponsored by MOBARTECH, an Italian research project – aimed at the co-construction of knowledge to foster understanding and interpretation of the cultural landscape from the point of view of the local community. The project led to the creation of a toolkit for citizens and tourists in which sound was the protagonist of several activities. Here we critically present insights and reflections on heritage, landscape and the sound in education.
Musica di paesaggi sonori. Enunciazione, risignificazione, comunicazione
Authors: Sillano Carlotta 
Published: August 2021

The paper – rapidly retracing some fundamental stages in the history of sound studies – questions the relationship between soundscape and music language and proposes a reflection on the resulting ontologies of sound. In the traditional conception of soundscape studies, musical language should contribute to a re-orchestration of environmental sound and should promote awareness and active listening of extra-musical sounds. However, every music composition or performance that draws on this kind of acoustic material, inevitably transforms its fruition. Immediacy is in fact impossible and each perception produces a new meaning. The article highlights the value of subjective perception and creative processes in the multidisciplinary discussion about soundscape.
Reflexo do planejamento tributário no endividamento das empresas não financeiras listadas na Brasil Bolsa Balcão (B3)
Authors: Da Fonseca Ayanna Karoline , Mendes Sirqueira Deylane , Alves de Macena Araújo Risolene , Santos Garcia Inajá Allane 
Published: August 2021

O objetivo deste estudo é investigar qual o reflexo do planejamento tributário no endividamento das empresas não financeiras listadas na B3. Para isso, utilizou-se o método da Regressão Quantílica e uma amostra com dados em painel, composta sob duas concepções do planejamento tributário: taxa de imposto efetiva (ETR) e ETR desembolsada (ETRCash). Sob a perspectiva da ETR, observou-se que, no menor quantil, empresas mais agressivas fiscalmente são menos endividadas do que aquelas que adotam planejamento tributário moderado. Enquanto, considerando a ETRCash, observou-se que práticas de planejamento fiscal agressiva estão associadas ao endividamento das empresas dos quantis menores. Acredita-se que tais empresas, mesmo não sendo favorecidas com altos créditos de terceiros, se utilizam do endividamento como estratégia para pagar menos tributos.
Genetic Diversity of HIV-1 and Transfusion Safety : Systematic Review and Concepts Analysis
Authors: Mangala Christian , Fokam Joseph , Bangola Denis Maulot , Nkoa Thérèse 
Published: August 2021

Background: The genetic diversity of human immunodeficiency virus type 1 (HIV-1) is a real problem facing blood banks. This genetic diversity has a negative impact on diagnostic strategies within the transfusion chain by weakening the security of the donation. The objective of this study is to clarify the concepts emanating from the research project entitled : «Genetic diversity of HIV-1 and its effect on the residual risk in blood transfusion in Gabon».
Methods: This study was the result of a systematic review and a conceptual analysis of several studies that were systematically searched for in databases (PubMed, Google Scholar, and Medline), and whose object was focused on the genetic diversity of HIV -1 and its impact on transfusion safety. Indeed, the information relating to the concepts coming from the full articles was used. These were obtained by reading the most relevant articles. All relevant studies reporting data on HIV-1 genetic diversity and blood safety published in English between January 2012 and December 2020 have been identified for context. The method of conceptual analysis of « Walker and Avant (2005) » was used to clarify the different concepts of our study. The correlation test was used to show the relationship between the concepts.
Results: This systematic review and conceptual analysis study made it possible to determine the variables and to clarify the different concepts (HIV-1, Genetic diversity, Blood transfusion, Residual risk) essential for carrying out our research project entitled: "Genetic diversity of HIV-1 and its effect on the residual risk in blood transfusion". This model made it possible to show the effect of the genetic diversity of HIV-1 on the residual risk in blood transfusion using as model variables : viral load and serological markers (Antibodies and P24 Antigen). Knowledge of molecular strains (URF, CRF, subtypes) during this study made it possible to better identify the molecular strains most involved in the residual risk. Despite its complexity, this conceptual analysis contributed enormously to the understanding of the activities and the quantifiable and non-quantifiable components that participated in our study. Statistical analysis showed that the HIV-1 concept was significantly related to the other three concepts with P = 0.001. Likewise for the concept of genetic diversity was also significantly linked to the two other concepts with P = 0.003.
Conclusion: The genetic diversity of HIV-1 in the blood transfusion environment contributes significantly to the transmission of HIV from donor to recipient. The mastery of these molecular strains is essential for the various blood banks to ensure a safe blood supply.
A Drug Use Evaluation Study on Antidepressants in Psychiatric Patients at a Tertiary Care Teaching Hospital
Authors: Hadia Rajesh , Sanghani Bhumin , Sajan Sushin , Mathew Tiji , Rathod Trupal , Joshi Dhaval , Maheshwari Rajesh , Baile Sunil , Kardani Sunil , Rajput Hemraj Singh 
Published: August 2021

Background: The pattern of prescribing Antidepressants to patients has been varying worldwide.
Objective: We aim to observe the prescribing pattern of antidepressants as well as assess its various outcomes in patients, the rationality of the prescriptions, and the prevalence of antidepressant usage.
Methodology: A prospective observational study of a total of 56 subjects receiving antidepressants was performed at the Psychiatry. They were screened for their various outcomes on using antidepressants. The written form of the medical record sheet was used to preserve the patient's Data. Prescription pattern, treatment chart, abnormal vitals were noted. Morisky's adherence scale was used to assess the adherence of patients to prescribed drugs. Hamilton depression rating scale was used to measure the patient's depressive stage. They were screened for possible ADRs. The causality and severity assessment of the observed ADRs was done by the WHO-UMC scale and Hartwig-Seigel scale respectively. Statistical analysis was done for all relevant data.
Results: In our study, the age of patients varies from 18 years to 85 years. The maximum number of patients were from the age group of 31-40 years [28.57% (N=16)]. The 50% (N=28) of patients were diagnosed with Depressive mood disorder. A total of 169 drugs were prescribed out of which 52.07% (N=88) were Antidepressant drugs. Out of 88 Antidepressant drugs, 20% (N=18) patients received Venlafaxine, followed by 17% (N=15) Escitalopram. Out of 56, 26.78% (N=15) showed low adherence, 41.07% (N=23) showed medium adherence and 32.14% (N=18) showed High adherence.41.07% (N=23) patients were identified with drug use problems. Adverse drug reactions were suspected in 25% (N=14) patients. The most common type of Adverse reaction due to the drug was Weight gain (N=6 patients). Paroxetine drug was found with the highest number of ADRs 28.57% (N=4).
Conclusion: Most common antidepressant prescribed was Venlafaxine. Most Patients in the community included suffered from Depressive mood disorder with a maximum number of patients appeared from the age group of the thirties to forties. Patients due to their unstable mental status were adhering to therapy at medium levels. Drug use problem was identified commonly with patients on sedatives resulting them to either forget taking the pills or missing the dose. Patients generally had a common Adverse drug reaction of weight gain. Proper lifestyle modifications and patient counselling is required to benefit patient from treatment.
Comparison of Complications between Direct Trocar Insertion Versus Veress Needle for Creation of Pneumoperitoneum in Patients Undergoing laparoscopic Cholecystectomy: A Randomized Control Trial
Authors: Hamid Kamran , Ahmad Shabbir , Khan Bahzad Akram , Answer Muhammad Faheem , Latif Amer , Naqvi Syed Mazhar Ali , Bhatti Muhammad Afzal , Rana Muhammad Asim , Hafeez Muhammad Mansoor 
Published: August 2021

Aim: To compare the outcomes in term of complication of Veress Needle Insertion (VNI) to Direct Trocar Insertion (DTI) for creation of pneumoperitoneum in laparoscopic cholecystectomy.
Design: Randomized controlled trial
Place and Duration of Study: The current analysis was conducted at Khawaja Muhammad Safdar Medical College Surgical Department, Allama Iqbal Memorial Hospital and Govt. Sardar Begum Teaching Hospital, Sialkot from September 27, 2017, to September 26, 2020.
Methodology: A total of six hundred and eight (n=608) patients, having age 30 to 75 years planned for laparoscopic cholecystectomy were included in this study. Patients were randomly divided into two groups, Group A (Direct Trocar Insertion), Group B (Veress Needle Insertion). Both groups had age and sex matched males and female. All trocars and veress needle used were disposable, with a safety shield. The primary outcome of our study was to compare the complications to assess the safety levels, while total time taken by the procedure and mean time for laparoscopic entry were the secondary end points. The collected data was analyzed by using software SPSS version 22. Chi-square test was used to check the significance of variance. P-value less than 0.05 remained the statistically significant.
Results: The complication rate in VNI group were significantly greater than the DTI group (p < 0.01), the duration of surgery between the two groups was not significantly different (p > 0.05), but we found statistically significant difference in mean laparoscope insertion time (DTI 3.4+ 1.4 versus VNI 4.8+ 0.7 minutes, p < 0.001).
Conclusion: From the results of our study, it can be concluded that the direct trocar insertion is a safe alternative to veress needle insertion in laparoscopic cholecystectomy as it is associated with fewer complications.
Giant Photo‐Magneto‐Thermoelectric Effect of End‐On Oriented PEDOT Grown from Self‐Assembled 3D Tectons
Authors: Kim Byeonggwan , Cho Cheolhyun , Han Minsu , Attias André‐Jean , Kim Eunkyoung 
Published: August 2021

AbstractConductive polymers (CPs) are arranged in the end‐on direction on graphene surfaces using 3D tectons of ZnPc assemblies, to control carrier transport from hot to cold via external magnetic fields. Poly(3,4‐ethylenedioxythiophene)s doped with tosylate are synthesized using monomer seeds that are complexed through pyridine units to 3D tectons on graphene via surface‐confined host‐guest chemistry, to provide an end‐on‐oriented polymer film on graphene with a high degree of crystallinity. The film shows free‐electron‐like charge transport properties, with an enhanced Hall mobility, and an increased Seebeck coefficient compared to the CP on graphene that is prepared without 3D tectons. A magneto‐thermoelectric (MTE) effect is reproducibly observed for the film device. Taking advantage of a large photothermal effect of the polymer film, a photon‐mode MTE effect is demonstrated for the first time. Both dark and photo‐MTE effects correlate well to the generated Lorentz force. These results provide a unique tool to program carrier transport in thin‐film via external magnetic stimuli with a temperature gradient.
Magnetization‐Switchable Implant System to Target Delivery of Stem Cell‐Loaded Bioactive Polymeric Microcarriers
Authors: Go Gwangjun , Yoo Ami , Kim Seokjae , Seon Jong Keun , Kim Chang‐Sei , Park Jong‐Oh , Choi Eunpyo 
Published: August 2021

AbstractVarious magnetic microcarrier systems capable of transporting cells to target lesions are developed for therapeutic agent‐based tissue regeneration. However, the need for bioactive molecules and cells, the potential toxicity of the microcarrier, and the large volume and limited workspace of the magnetic targeting device remain challenging issues associated with microcarrier systems. Here, a multifunctional magnetic implant system is presented for targeted delivery, secure fixation, and induced differentiation of stem cells. This magnetic implant system consists of a biomaterial‐based microcarrier containing bioactive molecules, a portable magnet array device, and a biocompatible paramagnetic implant. Among biomedical applications, the magnetic implant system is developed for knee cartilage repair. The various functions of these components are verified through in vitro, phantom, and ex vivo tests. As a result, a single microcarrier can load ≈1.52 ng of transforming growth factor β (TGF‐β1) and 3.3 × 103 of stem cells and stimulate chondrogenic differentiation without extra bioactive molecule administration. Additionally, the implant system demonstrates high targeting efficiency (over 90%) of the microcarriers in a knee phantom and ex vivo pig knee joint. The results show that this implant system, which overcomes the limitations of the existing magnetic targeting system, represents an important advancement in the field.
Modular‐Peptides‐Based Ternary Complex for Precisely Tracking the Targeted Process and Delivery of Gene/Chemo‐Drug
Authors: Hu Jing‐Jing , Yuan Qiming , Dong Xiaoqi , Cheng Yong , Yuan Lizhen , Dai Jun , Xia Fan , Lou Xiaoding 
Published: August 2021

AbstractHighly effective transporting and real‐time monitoring of the drug delivery system (DDS) has attracted much attention from researchers. However, separately tracking the multiple components in a complex DDS as well as its delivery process is challengeable. Here, a multi‐fluorescence‐labeled ternary complex is designed for delivering the therapeutic agents and monitoring the multiple components. Ternary complex (A@TR) is formed by three parts, including a) the carrier module TFD, which is a cell‐penetrating peptide (TAT) conjugated with anti‐cancer drug doxorubicin (DOX) and fluorescent molecule fluorescein isothiocyanate (FITC); b) therapeutic genes (ASO); c) the targeting module RDP based on a cyclic RGDFK peptide and aggregation‐induced‐emission luminogen PyTPE. The labeling of FITC through the covalent bond can stably track the location of anticancer drugs and genes in the long term. Meanwhile, the mark of PyTPE can monitor the process of targeting‐mediated endocytosis over time. After being internalized by tumor cells selectively, chemodrug and therapeutic genes can achieve a superior tumor inhibited effect. By utilizing the multi‐channel fluorescence, this ternary complex could achieve precisely monitoring the targeted binding process of DDS and delivery processes of therapeutic agents.
Metal‐Insulator‐Insulator‐Metal Diodes with Responsivities Greater Than 30 A W−1 Based on Nitrogen‐Doped TiOx and AlOx Insulator Layers
Authors: Alshehri Abdullah H. , Shahin Ahmed , Mistry Kissan , Ibrahim Khaled H. , Yavuz Mustafa , Musselman Kevin P. 
Published: August 2021

AbstractMetal‐insulator‐insulator‐metal diodes based on nitrogen‐doped titanium dioxide (NTiOx) and aluminum oxide (NAlOx) are fabricated and characterized for the first time. Pt/TiOx‐NTiOx/Pt and Pt/TiOx‐NAlOx/Pt diodes with 30 nm of TiOx or NTiOx and 5 nm of NAlOx are compared to undoped Pt/TiOx/Pt and Pt/TiOx‐AlOx/Pt diodes of similar thickness. The nitrogen atoms are expected to modify the barrier heights and produce electron traps in the insulators. This changes the conduction mechanisms of the doped diodes, including the introduction of unidirectional, defect‐mediated Poole–Frenkel transport and trap‐assisted tunneling, which increase the performance of the doped diodes. The representative figures of merit observed for a Pt/TiOx‐NAlOx/Pt diode at 0.5 V include an asymmetry of 8.76 × 103, nonlinearity of 4, and zero‐bias responsivity of 22.3 A W−1. Zero‐bias responsivities as high as 36.8 A W−1 are obtained, which surpass the 19.4 A W−1 theoretical limit for Schottky diodes. Notably, this defect‐engineering approach is found to improve the figures of merit without an unwanted increase in diode resistance. A thinner Pt/NTiOx‐NAlOx/Al diode is also produced, which has a low zero‐bias resistance of 36 Ω, nonlinearity of 3.7, and zero‐bias responsivity of 1.7 A W−1.
All‐Metal Oxide Transparent Photovoltaic for High‐Speed Binary UV Communication Window
Authors: Patel Malkeshkumar , Bhatnagar Priyanka , Bist Shristi , Kim Joondong 
Published: August 2021

AbstractOptoelectronic devices that are self‐powered and have a high transparency are of interest for application in versatile next‐generation “see‐through” platforms. However, current optoelectronic photodetectors often have drawbacks including a high driving power and a relatively slow response speed. In this work, large‐area transparent photovoltaic devices (TPVD) are reported that can be easily prepared at room temperature from eco‐friendly and abundant materials. The TPVD consists of a zinc oxide/nickel oxide heterostructure as the light‐harvester and ultraviolet (UV) blocker, and its photovoltaic performance is evaluated using silver nanowire (AgNW) electrodes composed of NWs with varying diameters. As a result of surface plasmons in the AgNW electrode, TPVDs with AgNWs that have a larger diameter exhibit enhanced transparency and photovoltaic performance, with a photovoltage of 520 mV under standard AM1.5 light illumination. Importantly, the binary electric signal produced can be decoded without the need for electronic filter circuits or a threshold. A UV communication system is further designed based on the TPVD for application as a self‐powered, binary Morse‐code signal with a high response speed. This work integrates the features of a transparent power generator and transparent optoelectronics into a UV photodetector, and it can enable the application of self‐reliant devices for communications, imaging, and sensors.
Asymptomatic Venous Thromboembolism After Hepatobiliary–Pancreatic Surgery: Early Detection Using D‐dimer and Soluble Fibrin Monomer Complex Levels
Authors: Hayashi Hikaru , Shimizu Akira , Kubota Koji , Notake Tsuyoshi , Sugenoya Shinsuke , Masuo Hitoshi , Hosoda Kiyotaka , Yasukawa Koya , Kobayashi Ryoichiro , Soejima Yuji 
Published: August 2021

AbstractAimThe aim was to investigate the usefulness of a preemptive management strategy that includes monitoring serum D‐dimer (DD) and soluble fibrin monomer complex (SFMC) levels for early detection and treatment of venous thromboembolism (VTE) after hepatobiliary–pancreatic (HBP) surgery.MethodsOverall, 678 patients who underwent HBP surgery between January 2010 and March 2020 were enrolled. Patients with increased postoperative serum DD or SFMC levels underwent contrast‐enhanced computed tomography, and those with VTE received anticoagulant agents. The VTE risk factors were investigated using multivariable analysis. Postoperative changes in DD and SFMC levels were verified, and their ability to identify VTE was evaluated using receiver operating characteristic (ROC) analysis.ResultsVTE developed in 83 patients (12.2%), and no symptomatic VTE or death due to VTE was observed. Multivariable analysis identified female sex (odds ratio [OR] 2.26; 95% confidence interval [CI] 1.41–3.60; P < .001) and surgery duration of ≥401 min (OR 2.07; 95% CI 1.27–3.35; P < .001) as independent risk factors for VTE. Maximum serum DD and SFMC levels in patients who developed VTE were significantly higher than those in patients without VTE (DD, 15.1 vs 8.9 μg/mL, P < .001; SFMC, 18.0 vs 10.2 μg/mL, P < .001, respectively). Both DD (n = 678) and the combination of DD and SFMC levels (n = 230) showed a good ability to detect VTE (area under the ROC curve, 0.804 and 0.761, respectively).ConclusionOur preemptive strategy of monitoring serum DD and SFMC levels enables early detection and treatment intervention of VTE after HBP surgery.