bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of elemental sulphur as an acidifying soil amendment for Brassica napus cultivation
Authors: López-Mosquera Mª Elvira , López-Fabal Adolfo , Illera Vives Marta , Seoane Labandeira Socorro 
Published: September 2021

Elemental sulphur is applied to alkaline soils as an acidifying material in order to improve nutrient availability and soil productivity. The oil industry extracts crude oils with ever higher concentrations of sulphur (S) that should not be released to the atmosphere and can be recovered by desulphurisation processes. The elemental S thus obtained has diverse applications, such as the manufacture of sulphuric acid, retreaded tyres, fungicides and acidifying agents. When used as a soil acidifying agent, S undergoes an oxidation process that depends on several soil-related factors: temperature, aeration, texture and organic matter content. The most important parameter appears to be the particle size of the S form applied to the soil. This study investigated the acidifying effects of two forms of elemental S, derived from an oil refinery, on an alkaline soil planted with oilseed rape. A trial was established in 300 L containers maintained outdoors in a site that received more than 1000 mm of precipitation during the study period, between October and the end of April. The treatments consisted of powdered (&lt;0.5 mm) S at a dose of 1.5 t ha<sup>-1</sup>, and sieved (0.5-2 mm) S at doses of 3 and 5 t ha<sup>-1</sup>. Control soils were not treated with sulphur. The effects of the different treatments were studied by analysing leachates collected after every episode of rain during the crop cycle, foliar analysis of the crop produced, quantification of seed production and oil yield, and, finally, analysis of aqueous extracts of the soil obtained after harvesting the crop. The results obtained show that under the study conditions, sieved S (0.5-2 mm) was at least as effective as powdered S as a treatment for acidifying the alkaline calcareous soil used in the study. The sieved form offers two advantages relative to the powdered form: it requires less grinding and its storage and distribution in the field are simpler because the material does not disperse in the air (as the particles are larger) and is not explosive.
Biomass assessment in annelids: A photogrammetric method suitable for hatchlings and adults developed for Eisenia andrei
Authors: Ortega Hidalgo Maria Mercedes , Iparraguirre Bolaños Esther , Brea San-Nicolás Carlos 
Published: September 2021

A simple photogrammetric, non-destructive method for measuring individual biomass in tubular soft-bodied organisms has been developed using <em>Eisenia andrei</em>. Photographic procedures can be easily performed with low cost digital cameras and the number of pictures to be processed can be reduced to two per animal (Variation Coefficient ≤ 3.5%) even at sizes ~10 mg live weight. Image analysis was undertaken using CobCal 2.0© software. No bias was induced by body position. Accuracy in terms of the regression coefficient of the equation (<em>y</em>=a*<em>x</em><sup>b</sup>) relating portrayed area (mm<sup>2</sup>) to live weight (mg) was 98%. Two different procedures were designed for laboratory and field uses. No differences between methods appeared at sizes over eight mg live weight, resulting in a common function relating image area to live weight results (PS = 3.27*LW<sup>0.681</sup>). Below 8 mg, the weight exponent remained unchanged but the value for the elevation rose to 4.21 indicating an increase of surface exposure to the camera lens in newly-hatched worms: the visible part of the geometric area (cylinder shape) enlarged from 34% to 43.52%. As a conclusion this non-invasive procedure proved suitable for worms ranging from sizes of 0.2 to 3 000 mg live weight to determine biometric parameters such as length, volume, surface or body weight, which are key factors for interpreting physiological responses to underlying growth patterns.
Transfer of natural radionuclides from soil to plants in Savar Dhaka
Authors: Haque M. , Ferdous J. 
Published: September 2021

The radioactivity of environmental samples from nuclear reactor sites must be analyzed before the public is given free access to the plants grown in these soils. Plant and corresponding soil samples were collected from a sample site around the Savar research reactor near Dhaka (Bangladesh) and the activity concentrations of natural radionuclides <sup>226</sup>Ra (<sup>238</sup>U-chain), <sup>228</sup>Ra (<sup>232</sup>Th-chain) and non-chained <sup>40</sup>K were measured using gamma ray spectrometry. Soils of Savar contained more radioactive <sup>40</sup>K than <sup>226</sup>Ra and <sup>228</sup>Ra. The influence of certain soil properties on the activity concentrations and transfer factors (TF) of natural radionuclides were investigated by correlating the observed data with those of soil properties. The activity concentrations of <sup>40</sup>K were much higher than those of <sup>226</sup>Ra and <sup>228</sup>Ra in plants due to higher uptake from soils. The transfer factors for <sup>226</sup>Ra, <sup>228</sup>Ra and <sup>40</sup>K were found to range from 0.04 to 0.10, 0.12 to 0.32, and 0.24 to 0.72, respectively. The soil to plant transfer factors for <sup>40</sup>K was found to be much higher in plants, which might be due to this element being vital in plants. This study showed that activity concentrations of these radionuclides in plants and their plant transfer factors seem to depend on the activity concentrations of the same radionuclides in soil.</p><p><strong> </strong>
16. YÜZYIL ŞAİRLERİNDEN KARA FAZLÎ’NİN TEHNİYET-NÂME’Sİ
Authors: YALÇINKAYA Mehmet Akif 
Published: September 2021

Kanuni devri şairlerinden biri olan Kara Fazlî, Divan’ından ziyade Gül ü Bülbül mesnevisiyle tanınmıştır. Kanuni’nin oğulları Şehzâde Mehmed, Şehzâde Mustafa ve Şehzâde Selim’in divan kâtipliğini yapmış, ömrünün son yıllarında reîs-i küttâblık makamına terfi etmiştir. Vazifesi gereği pek çok mektup kaleme almış ve devrinin muteber münşileri arasında yerini almıştır. Manzum-mensur muhtelif eserler telif eden Kara Fazlî’nin inşâ sahasındaki eserlerinden birisi de Rumeli Tımarlarına defterdar olarak atanan Ahmed Çelebi bin Mehmed isimli bir paşayı tebrik maksadıyla yazdığı Tehniyet-nâme’sidir. Mektup, Süleymaniye Kütüphanesi Âşir Efendi bölümü 314/III numarada kayıtlı mecmuanın 85b-92b varakları arasında yer almaktadır. Kara Fazlî, mektubunda bu terfi haberinden duyduğu sevinci samimi bir üslupla dile getirir. Mezkûr paşanın güzel hasletlerinden övgüyle söz eder. Ulu kimselerin meclislerinde büyüklere hediye sunmanın kadim bir adet olduğunu ve bu vesileyle bu Tehniyet-nâme’yi hediye kabilinden arz ettiğini belirtir. Mektubun muhatabını metheden bir kaside ile sözlerini noktalar. Mektupta Arapça ve Farsça tamlamalarla yüklü sanatlı bir dil kullanılmıştır. Konunun akışına uygun olarak ayet, hadis ve bir kısmı müellifin kendine ait, bir kısmı ise Arap ve Fars edebiyatlarından berceste kabilinden muhtelif şairlere ait çeşitli nazım şekillerinde şiirlere yer verilmiştir.
Bu makalede önce Kara Fazlî’nin hayatı ve eserleri hakkında bilgiler verilmiştir. Ardından eserin nüshası tanıtılarak mektup muhteva yönünden incelenmiş, çalışmanın sonunda mektubun transkripsiyonlu metni sunulmuştur.
A Case Control Study on Serum Level of Micronutrients in Decompensated Liver Cirrhosis Patients in Mymensingh, Bangladesh
Authors: Hossain Md Shahadath , Rahman Md Muzibar , Shahidullah ASM , Sen Bina , Hoque Md Rafiqul , Paul Arup Ratan , Saha Kamona Rani 
Published: September 2021

Liver cirrhosis is an end stage condition of liver disease and the leading cause of death for both men and women all over the world. It causes death due to acute or chronic gastrointestinal blood loss & multi organ failure. The aim of the study is to evaluate the serum Copper, Zinc and Iron levels in patients with liver cirrhosis. A total 120 subjects were included in this study. Among them, 60 diagnosed decompensated liver cirrhosis patients denoted as case group (n=60) and 60 were normal healthy individuals denoted as control group (n=60), both the case and control groups were male because liver cirrhosis occurs rarely female in Bangladesh. The subjects were briefed and written consents were taken. Under all aseptic precaution 5 ml of venous blood was collected from median cubital vein, analysis was carried out in the Department of Biochemistry, Mymensingh Medical College, Mymensingh, over a period of one year from July 2015 to June 2016. All statistical analysis was performed by SPSS windows package, version 20. Significance of the difference between two groups were evaluated by using student's unpaired 't' test. All the values were expressed as mean ± SD and P value 0.05 was taken as the level of significance. After careful evaluation, in the present study we found significant increase in the serum Copper levels and significant decreases in the serum Zinc and Iron levels in liver cirrhosis patients when compared with that of control group. It can be concluded that to overcome fatal consequences of decompensated liver cirrhosis patients we should avoid high Copper containing food provides Zinc and Iron supplementation as well as blood transfusion may be beneficial.
CBMJ 2019 July: Vol. 08 No. 02 P: 10-16
Prediction of the Risk Factors of Knee Injury During Drop-Jump Landing With Core-related Measurements in Amature Basketball Players
Authors: Guo Liang , Zhang Jing , Wu Ying , Li Li 
Published: September 2021

Purpose: To evaluate the relationship between specific aspects of core stability and knee injury risk factors during drop-jump (DJ) landing.Methods: Eighteen college-aged male amateur basketball players participated in the project. Kinetic and kinematic data for DJ tasks were collected with force plates and infrared cameras. Raw data were processed to calculate knee joint angles and joint moments during DJ landing. Different components of core stability were represented by the sit-ups in 20 s (SU), trunk extensor endurance, trunk flexion and extension range of motion, dominant extremity single-leg stance time (DLS), and dominant extremity single-leg hop distance, respectively.Methods: Correlation and regression were used to determine the relationship between jumping-related biomechanical parameters and core stability components.Results: SU shared significant variance with the peak moment of knee extension (PMKE, p &lt; 0.05), the peak moment of knee abduction (PMKA, p &lt; 0.05), and the angle of knee internal rotation at initial contact (AKRI, p &lt; 0.05). DLS shared significant variance with the angular motion of knee internal rotation (AMKR, p &lt; 0.05) and the AKRI (p &lt; 0.01). SU and DLS together could explain 52% of the variance observed in the AKRI, and the result was significant.Conclusion: Core stability’s strength and motor control aspects played an essential role in preventing knee injury during DJ landing. An integrative training program addressing core strength and motor control could be considered for coaches and athletes to prevent knee injury through core training and conditioning.
The Therapeutic Potential of Mesenchymal Stromal Cells for Regenerative Medicine: Current Knowledge and Future Understandings
Authors: Merimi Makram , El-Majzoub Rania , Lagneaux Laurence , Moussa Agha Douâa , Bouhtit Fatima , Meuleman Nathalie , Fahmi Hassan , Lewalle Philippe , Fayyad-Kazan Mohammad , Najar Mehdi 
Published: September 2021

Graphical AbstractThe road map of MSC review.
Genotype Distribution Change After Human Papillomavirus Vaccination in Two Autonomous Communities in Spain
Authors: Freire-Salinas Javier , Benito Rafael , Azueta Ainara , Gil Joaquina , Mendoza Claudia , Nicolás Montserrat , García-Berbel Pilar , Algarate Sonia , Gómez-Román Javier 
Published: September 2021

ContextIt has been more than 10 years since the human papillomavirus (HPV) vaccination program was initiated in most advanced countries. Thus, it seems necessary to change the uterine cervical cancer screening strategy. Molecular-based tests are considered essential in this scenario.ObjectiveWe aimed to review the distribution of the HPV genotypes after the introduction of the vaccination program with Cervarix® and Gardasil 4® in two autonomous communities in Spain, looking for possible changes in distribution and the occurrence of a herd effect.DesignA cross-sectional study was performed in 45,362 samples that were processed in the Cantabria and Aragon communities during the period from 2002 to 2016. We compared the genotype distribution before and after the vaccination program was initiated.ResultsGenotypes HPV6 and HPV11 have decreased significantly after the introduction of the vaccine. HPV16 has had a decrease, but not a significant one in the statistical analysis. However, HPV31, HPV52, and HPV45 have increased in percentage. A replacement phenomenon with other genotypes not included in the vaccine has been observed in our population.ConclusionsContinued surveillance is needed to provide further indication of any changes over time in the genotypes in circulation. This will be facilitated by monitoring the genotyping results from the new model of cervical screening using primary HPV DNA testing.
Comparison of the Ocular Microbiomes of Dry Eye Patients With and Without Autoimmune Disease
Authors: Qi Yun , Wan Yong , Li Tianhui , Zhang Ming , Song Yu , Hu Yaguang , Sun Yining , Li Li 
Published: September 2021

PurposeThe pathogenesis of dry eye concomitant with autoimmune disease is different from that of dry eye without autoimmune disease. The aim of this study was to explore differences in the microbiota diversity and composition in dry eye with and without autoimmune disease.MethodsSwab samples from the inferior fornix of the conjunctival sac were obtained from dry eye patients without autoimmune disease (n = 49, dry eye group) and from those with autoimmune disease (n = 38, immdry eye group). Isolated bacterial DNAs from swabs were analyzed with 16S rRNA amplicon sequencing.ResultsAnalysis of the alpha diversity revealed no significant differences between subjects in the dry eye and immdry eye groups. Those in the immdry eye group had a distinct microbial composition compared with those in the dry eye group. The combination of the genera Corynebacterium and Pelomonas distinguished subjects in the immdry eye group from those in the dry eye group, with an area under the curve of 0.73 (95% CI = 0.62–0.84). For the same bacteria, the correlations between microbe abundance and the ocular surface parameters were different in the two groups. In addition, the functions of the microbial communities were altered in the two groups.ConclusionsOur study demonstrates changes in the composition and function of the ocular microbiome between subjects in the immdry eye and dry eye groups, which suggests that the potential pathogenesis is different.
The Integrative Analysis of Competitive Endogenous RNA Regulatory Networks in Coronary Artery Disease
Authors: Ji Yuyao , Yan Tao , Zhu Shijie , Wu Runda , Zhu Miao , Zhang Yangyang , Guo Changfa , Yao Kang 
Published: September 2021

Background: Coronary artery disease (CAD) is the leading cause of cardiovascular death. The competitive endogenous RNAs (ceRNAs) hypothesis is a new theory that explains the relationship between lncRNAs and miRNAs. The mechanism of ceRNAs in the pathological process of CAD has not been fully elucidated. The objective of this study was to explore the ceRNA mechanism in CAD using the integrative bioinformatics analysis and provide new research ideas for the occurrence and development of CAD.Methods: The GSE113079 dataset was downloaded, and differentially expressed lncRNAs (DElncRNAs) and genes (DEGs) were identified using the limma package in the R language. Weighted gene correlation network analysis (WGCNA) was performed on DElncRNAs and DEGs to explore lncRNAs and genes associated with CAD. Functional enrichment analysis was performed on hub genes in the significant module identified via WGCNA. Four online databases, including TargetScan, miRDB, miRTarBase, and Starbase, combined with an online tool, miRWalk, were used to construct ceRNA regulatory networks.Results: DEGs were clustered into ten co-expression modules with different colors using WGCNA. The brown module was identified as the key module with the highest correlation coefficient. 188 hub genes were identified in the brown module for functional enrichment analysis. DElncRNAs were clustered into sixteen modules, including seven modules related to CAD with the correlation coefficient more than 0.5. Three ceRNA networks were identified, including OIP5-AS1-miR-204-5p/miR-211-5p-SMOC1, OIP5-AS1-miR-92b-3p-DKK3, and OIP5-AS1-miR-25-3p-TMEM184B.Conclusion: Three ceRNA regulatory networks identified in this study may play crucial roles in the occurrence and development of CAD, which provide novel insights into the ceRNA mechanism in CAD.
Genomic Prediction of Two Complex Orthopedic Traits Across Multiple Pure and Mixed Breed Dogs
Authors: Jiang Liping , Li Zhuo , Hayward Jessica J. , Hayashi Kei , Krotscheck Ursula , Todhunter Rory J. , Tang You , Huang Meng 
Published: September 2021

Canine hip dysplasia (CHD) and rupture of the cranial cruciate ligament (RCCL) are two complex inherited orthopedic traits of dogs. These two traits may occur concurrently in the same dog. Genomic prediction of these two diseases would benefit veterinary medicine, the dog’s owner, and dog breeders because of their high prevalence, and because both traits result in painful debilitating osteoarthritis in affected joints. In this study, 842 unique dogs from 6 breeds with hip and stifle phenotypes were genotyped on a customized Illumina high density 183 k single nucleotide polymorphism (SNP) array and also analyzed using an imputed dataset of 20,487,155 SNPs. To implement genomic prediction, two different statistical methods were employed: Genomic Best Linear Unbiased Prediction (GBLUP) and a Bayesian method called BayesC. The cross-validation results showed that the two methods gave similar prediction accuracy (r = 0.3–0.4) for CHD (measured as Norberg angle) and RCCL in the multi-breed population. For CHD, the average correlation of the AUC was 0.71 (BayesC) and 0.70 (GBLUP), which is a medium level of prediction accuracy and consistent with Pearson correlation results. For RCCL, the correlation of the AUC was slightly higher. The prediction accuracy of GBLUP from the imputed genotype data was similar to the accuracy from DNA array data. We demonstrated that the genomic prediction of CHD and RCCL with DNA array genotype data is feasible in a multiple breed population if there is a genetic connection, such as breed, between the reference population and the validation population. Albeit these traits have heritability of about one-third, higher accuracy is needed to implement in a natural population and predicting a complex phenotype will require much larger number of dogs within a breed and across breeds. It is possible that with higher accuracy, genomic prediction of these orthopedic traits could be implemented in a clinical setting for early diagnosis and treatment, and the selection of dogs for breeding. These results need continuous improvement in model prediction through ongoing genotyping and data sharing. When genomic prediction indicates that a dog is susceptible to one of these orthopedic traits, it should be accompanied by clinical and radiographic screening at an acceptable age with appropriate follow-up.
Development and Validation of Predictors for the Survival of Patients With COVID-19 Based on Machine Learning
Authors: Zhao Yongfeng , Chen Qianjun , Liu Tao , Luo Ping , Zhou Yi , Liu Minghui , Xiong Bei , Zhou Fuling 
Published: September 2021

Background: The outbreak of COVID-19 attracted the attention of the whole world. Our study aimed to explore the predictors for the survival of patients with COVID-19 by machine learning.Methods: We conducted a retrospective analysis and used the idea of machine learning to train the data of COVID-19 patients in Leishenshan Hospital through the logical regression algorithm provided by scikit-learn.Results: Of 2010 patients, 42 deaths were recorded until March 29, 2020. The mortality rate was 2.09%. There were 6,812 records after data features combination and data arrangement, 3,025 records with high-quality after deleting incomplete data by manual checking, and 5,738 records after data balancing finally by the method of Borderline-1 Smote. The results of 10 times of data training by logistic regression model showed that albumin, saturation of pulse oxygen at admission, alanine aminotransferase, and percentage of neutrophils were possibly associated with the survival of patients. The results of 10 times of data training including age, sex, and height beyond the laboratory measurements showed that percentage of neutrophils, saturation of pulse oxygen at admission, alanine aminotransferase, sex, and albumin were possibly associated with the survival of patients. The rates of precision, recall, and f1-score of the two training models were all higher than 0.9 and relatively stable.Conclusions: We demonstrated that percentage of neutrophils, saturation of pulse oxygen at admission, alanine aminotransferase, sex, and albumin were possibly associated with the survival of patients with COVID-19.
Gait-Related Brain Activation During Motor Imagery of Complex and Simple Ambulation in Parkinson's Disease With Freezing of Gait
Authors: Huang Hui-Chun , Chen Chun-Ming , Lu Ming-Kuei , Liu Bey-Ling , Li Chia-Ing , Chen Jui-Cheng , Wang Guei-Jane , Lin Hsiu-Chen , Duann Jeng-Ren , Tsai Chon-Haw 
Published: September 2021

Background: Freezing of gait (FOG) in Parkinson's disease (PD) is a devastating clinical phenomenon that has a detrimental impact on patients. It tends to be triggered more often during turning (complex) than during forwarding straight (simple) walking. The neural mechanism underlying this phenomenon remains unclear and requires further elucidation.Objective: To investigate the differences in cerebral functional magnetic resonance imaging responses between PD patients with and without FOG during explicitly video-guided motor imagery (MI) of various complex (normal, freezing) and simple (normal, freezing) walking conditions.Methods: We recruited 34 PD patients, namely, 20 with FOG and 14 without FOG, and 15 normal controls. Participants underwent video-guided MI of turning and straight walking, with and without freezing, while their brain blood oxygen level-dependent (BOLD) activities were measured. Gait analysis was performed.Results: While comparing FOG turning with FOG straight walking, freezers showed higher activation of the superior occipital gyrus, left precentral gyrus, and right postcentral gyrus compared with non-freezers. Normal controls also manifest similar findings compared with non-freezers, except no difference was noted in occipital gyrus activity between the two groups. Freezers also displayed a higher effect size in the locomotor regions than non-freezers during imagery of normal turning.Conclusions: Our findings suggest that freezers require a higher drive of cortical and locomotion regions to overcome the overinhibition of the pathways in freezers than in non-freezers. Compared with simple walking, increased dorsal visual pathway and deep locomotion region activities might play pivotal roles in tackling FOG in freezers during complex walking.