bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evolution of medication consumption in a working environment in France: Results of the four waves of the “Drugs and Work” study (1986–2016)
Authors: Herin Fabrice , Othenin Jerome , Jouanjus Emilie , Rousseau Vanessa , Niezborala Michel , Lapeyre‐Mestre Maryse 
Published: February 2021

AbstractObjectivesPrevious studies in the working environment have underlined the high prevalence of drug consumption. The aim of this study was to present the main characteristics of this consumption in French workers and to identify changes from the 1986, 1996, 2006 and 2016 surveys.MethodsThe design was a repeated cross‐sectional study in 1986, 1996, 2006 and 2016. At each wave, demographic and socio‐professional characteristics, self‐reported consumption of medications during the week before the occupational medical visit, and perceived difficult working conditions and extraprofessional problems were collected among a sample of workers. Factors associated with consumption of any drug and of main therapeutic classes were investigated through multivariate logistic regression models, using 2016 as the reference for investigating temporal trends.ResultsPrevalence of use of any drug was significantly higher in 2016, with marked changes observed in comparison with 1986: absolute decrease of psychotropic (−5.1%, p < 0.0001), antibiotics (−2.7%, p < 0.0001) and cardiovascular drug use (−3.8%, p < 0.0001), increase of analgesic use (+8.3%, p < 0.0001). Difficult working conditions, age and female gender were independently associated with analgesic drug use, and extraprofessional problems and female gender associated with psychotropic drug use.ConclusionsThis analysis of self‐reported drug use in the working environment illustrates the global patterns of medication use in a French active population over 3 decades. The favorable development in the level of consumption of psychotropic drugs should not underestimate the attention to be paid to the determinants of chronic consumption, or possible transfers to less stigmatized medications.
Outpatient insulin‐related adverse events due to mix‐up errors: Findings from two national surveillance systems, United States, 2012–2017
Authors: Geller Andrew I. , Conrad Ariane O. , Weidle Nina J. , Mehta Hina , Budnitz Daniel S. , Shehab Nadine 
Published: February 2021

AbstractPurposeWe used data from two public health surveillance systems for national estimates and detailed descriptions of insulin mix‐up errors resulting in emergency department (ED) visits and other serious adverse events to help inform prevention efforts.MethodsED visits involving patients seeking care for insulin medication errors collected by the NEISS‐CADES project in 2012–2017 and voluntary reports of serious insulin medication errors submitted to the US Food and Drug Administration (FDA) in 2016–2017 were analyzed. National estimates of insulin product prescriptions dispensed from retail pharmacies were obtained from IQVIA National Prescription Audit.ResultsBetween 2012 and 2017, based on 514 NEISS‐CADES cases, there were an estimated 5636 (95% CI, 4143‐7128) ED visits annually for insulin mix‐up errors; overall, over three‐quarters (77.5%; 95% CI, 71.6%–83.3%) involved taking rapid‐acting instead of long‐acting insulin. Between 2012 and 2017, the proportion of mix‐up errors among all estimated ED visits for all insulin errors decreased by 60%; concurrently, the proportion of pens among all insulin package types dispensed increased by 50%. Among 58 voluntary reports submitted to FAERS, over one‐half (56.9%) of cases involved taking rapid‐ instead of long‐acting insulin. Among 27 cases with documented contributing factors, approximately one‐half involved patients having difficulty differentiating products.ConclusionsAmong all ED visits for insulin errors collected by NEISS‐CADES in 2012–2017, the proportion involving mix‐up errors has declined. Continued reductions may require additional prevention strategies, including improving insulin distinctiveness, particularly for rapid‐ vs long‐acting insulins. Ongoing national surveillance is important for identifying the impact of interventions.
Prolonged survival in advanced squamous cell lung carcinoma by rational and standardized treatment: A case report of long‐term survival in a patient with NSCLC
Authors: Ji Min , Shi Yue , Zou Renrui , Jiang Yingying , Wang Li , Ma Rong , Zhang Xiuming , Zhu Xiangzhi , Chen Cheng , Shi Meiqi , Wang Xiaohua , Feng Jifeng 
Published: February 2021

AbstractObjectiveTo report the treatment of a long‐term survival case of stage IV lung squamous cell carcinoma (LSCC) patient with multiorgan metastases, including intrapulmonary, brain, liver, bone, and multiple lymph nodes.Methods and resultsA 72‐year‐old male patient with stage IV LSCC achieved a total survival of 85 months with comprehensive treatment of chemotherapy, radiotherapy, targeted, and immunotherapy.ConclusionFull‐course management, multidisciplinary diagnosis and treatment, and rational application of multiple treatment measures can improve the quality of life of the patient with advanced lung cancer and prolong their survival.
Annual analysis of field‐evolved insecticide resistance in Bemisia tabaci across China
Authors: Zheng Huixin , Xie Wen , Fu Buli , Xiao Si , Tan Xing , Ji Yao , Cheng Jiaxu , Wang Ran , Liu Baiming , Yang Xin , Guo Zhaojiang , Wang Shaoli , Wu Qingjun , Xu Baoyun , Zhou Xiaomao , Zhang Youjun 
Published: February 2021

AbstractBACKGROUNDOver recent decades, many efficacious insecticides have been applied for control of Bemisia tabaci, one of the most notorious insect pests worldwide. Field‐evolved insecticide resistance in B. tabaci has developed globally, but remains poorly understood in China.RESULTSIn this study, a total of 30 field samples of the whitefly Bemisia tabaci from eight provinces of China were collected in 2015 to 2018. Twenty‐four of the populations were identified as Mediterranean, ‘Q’ type (MED), three were Middle East‐Asia Minor 1, ‘B’ type (MEAM1), and three were mixtures of MED/ MEAM1. After identifying whether they belong to MED or MEAM1, the selected individuals were used in bioassays assessing insecticide resistance to abamectin, thiamethoxam, spirotetramat, cyantraniliprole, and pyriproxyfen. Our results showed that all populations in the eight regions had little or no resistance to abamectin; abamectin resistance was highest in the Hunan (Changsha) and Hubei (Wuhan) regions and was lowest in the island region of Hainan (Sanya). The resistance of B. tabaci to spirotetramat, cyantraniliprole, and pyriproxyfen increased each year. The resistance to thiamethoxam remained low because of the high LC50 value for the laboratory strain.CONCLUSIONThese findings suggest that a rotation system using efficacious B. tabaci insecticides with differing mode of actions ought to be implemented for sustainable control to reduce the potential of resistance development. This study provides important data to support the integrated pest management and insecticide resistance management of B. tabaci in China.© 2021 Society of Chemical Industry.
Can the banana weevil Cosmopolites sordidus be a vector of Fusarium oxysporum f.sp. cubense race 1? Unravelling the internal and external acquisition of effective inoculum
Authors: Guillen Sánchez César , Tixier Philippe , Tapia Fernández Ana , Conejo Barboza Ana Maria , Sandoval Fernández Jorge A , de Lapeyre de Bellaire Luc 
Published: February 2021

AbstractBACKGROUNDWith the undergoing world outbreak of Fusarium wilt of bananas, it is essential to unravel all the possible process of dissemination of this disease. The host‐pest interactions of the banana weevil with banana plants make this insect an important potential vector. This study, carried out in controlled conditions, explores the interaction between the banana weevil and Fusarium oxysporum f.sp. cubense race 1 (Foc), with a focus on the external and internal transport of viable fungal propagules.RESULTSViable inoculum of Foc was detected very rapidly on external teguments and in the digestive tract of the insect, i.e. at the lowest time studied of 5 min after contact with infected pseudostems. Maximal inoculum acquisition occurred after 1 h contact with an inoculum source. External inoculum was higher than the inoculum present in the digestive tract, but external and internal inoculum had the same dynamics. After a contact of an infected source, external and internal inoculum decreased exponentially within 50 h, but weevils remained infested for a long time, as long as 2 or 3 days that would be enough for inoculum dispersal. Viable inoculum was also detected in feces. Foc strains isolated were pathogenic when inoculated to banana plants of the Gros Michel variety but did not provoke any symptom on Cavendish banana plants.CONCLUSIONThese results demonstrate that the infective structures of Foc remain externally viable in the digestive system and the excreta of the banana weevil. Such excreta are capable of making healthy banana plants of the Gros Michel variety.© 2021 Society of Chemical Industry.
Mobile life and family. The impact of ICTs on spatial‐geographic mobility
Authors: Garcia Moreno José Manuel 
Published: February 2021

AbstractThe family is in a constant process of adaptation to the structural changes brought about by the network society, such as the digitalization of social relationships as a result of the extension of Information and Communication Technologies (ICTs). The aim of this study is to examine the process of spatial‐geographic mobility in Spain supported by ICTs within the family. To meet this objective, data from two studies by the Spanish Center for Sociological Research (2015 and 2016) focused on understanding the Impact of ICTs on the Family in Spain were analysed. The results indicate that the probability of moving geographically is greater when instant messaging software and digital social networks are used within the family. Differences are found in sociodemographic and social status factors. The probability of moving geographically increases when the use of ICTs enables families to become more efficient and competent and when their social capital increases.
5.3: Invited Paper: High Efficiency Phase Modulators
Authors: Lu Jiangang , Luo Yuxiang , Huang Kai 
Published: February 2021

In communication networks, wavelength selective switch (WSS) is one of the key components in reconfigurable optical add‐drop multiplexer (ROADM) [1]. Several technologies have been developed to achieve a high‐performance WSS, such as micro electromechanical systems (MEMS) [2], liquid crystal on silicon (LCOS) [3], arrayed waveguide grating (AWG) [4], and hybrid planar lightwave circuit (PLC)‐MEMS [5]. Among these, LCOS‐based WSS is most attractive for the next‐generation optical networks due to its controllability with individual electrical control on pixel. It shows advantages of flexible bandwidth adjustment, adaptive alignment, and robustness without mechanical movements.A LCOS exhibiting a high diffraction efficiency at a large deflection angle is demonstrated [6]. A liquid crystal (LC) mixture with a large birefringence (Δn = 0.27, at λ = 1550 nm) and a large dielectric constant (Δε = 10.4) is developed to obtain the high‐phase retardation, more than 4π, at 1550 nm within a relatively low operation voltage of 5.5 V on LCOS. When compared with the conventional modulation method of 2π phase retardation, both grating period and phase retardation are doubled in 4π modulo modulation. Using the high‐phase retardation modulation method, the LCOS may achieve high diffraction efficiency, more than 56.6% at 4.5° deflection angle of C‐band wavelength with an optimized phase retardation profile.A polarization‐independent blue phase liquid crystal on silicon (BPLCoS) device with low operation voltage for 2π phase depth is proposed [7]. With optimized reflection structure and two reflection films, the incident light may experience multifold optical path and 2π phase depth can be obtained. For the polarization‐independence, an inclined electric field made by periodical gradient voltage is applied on the blue phase liquid crystal (BPLC) to match the light propagation direction. With the structure, the operation voltage can be lowered to 5.5 V in simulation and 5.9 V in experiment for 2π phase modulation at 1550 nm.The high diffraction efficiency and polarization‐independent phase modulators show the great potential application of beam steering for the optical communication and the holographic display.
P‐15.4: Virtual reality gesture recognition based on depth information
Authors: Yu Xiaoyang , Jiang Lin , wang Lijun 
Published: February 2021

With the rapid development of computer technology, the information revolution is constantly affecting and changing our lives. Today's virtual reality technology is no longer just a virtual model for viewing. Experiencers are more willing to personally interact with the virtual environment in a virtual scene to increase their sense of gaming experience.Today's virtual reality interaction methods mainly interact through the handles that come with VR helmets. Previously, some scholars have researched gesture interaction in virtual environments. They use data gloves to obtain information about hand movements. This method makes users have to wear heavy data gloves, which limits the natural movement of their hands. To overcome this shortcoming, the need for low‐cost vision‐based virtual reality gesture interaction is becoming more and more urgent.Traditional gesture recognition technologies based on artificial modeling include template‐based matching, data‐based gloves, and machine learning. As machine learning gesture classifiers, Hidden Markov Model (HMM) and Support Vector Machine (SVM) [1] have been widely used. However, in the hand motion detection of ordinary cameras, the image is prone to speckles, lighting changes, and other factors, which seriously affects the performance of the classifier, making it difficult to accurately and efficiently detect the first image when the background is complex and the lighting is affected. In recent years, deep learning‐based object detection methods have achieved great breakthroughs [2]. In the past decade, many deep learning‐based dynamic gesture recognition algorithms have been introduced. In the case of changing lighting conditions, in order to improve the classification accuracy of gesture recognition [3]. Therefore, this article chooses a depth camera combined with HTC VIVE device for gesture recognition in virtual reality. First obtain the depth image of the hand through the depth camera, then label the depth image, and then learn through the deep learning network hand movement training [4], preprocess the detected human hand image, and recognize it by hand detection The position of the hand in the image is obtained, and the movement of the hand is recognized as a result of recognition.The algorithm in this paper uses the advanced deep learning network YOLOv3, and changes the network structure and multiscale structure based on the original network. This algorithm is compared with other deep learning algorithms for gesture recognition, and the recognition effect is better than other algorithms in the same category.
Stretchable Energy Storage Devices Based on Carbon Materials
Authors: Li Luhe , Wang Lie , Ye Tingting , Peng Huisheng , Zhang Ye 
Published: February 2021

AbstractStretchable energy storage devices are essential for developing stretchable electronics and have thus attracted extensive attention in a variety of fields including wearable devices and bioelectronics. Carbon materials, e.g., carbon nanotube and graphene, are widely investigated as electrode materials for energy storage devices due to their large specific surface areas and combined remarkable electrical and electrochemical properties. They can also be effectively composited with many other functional materials or designed into different microstructures for fabricating stretchable energy storage devices. This review summarizes recent advances toward the development of carbon‐material‐based stretchable energy storage devices. An overview of common carbon materials’ fundamental properties and general strategies to enable the stretchability of carbon‐material‐based electrodes are presented. The performances of the as‐fabricated stretchable energy storage devices including supercapacitors, lithium‐ion batteries, metal–air batteries, and other batteries are then carefully discussed. Challenges and perspectives in this emerging field are finally highlighted for future studies.
QQ-system and Weyl-type transfer matrices in integrable SO(2r) spin chains
Authors: Ferrando Gwenaël , Frassek Rouven , Kazakov Vladimir 
Published: February 2021

Abstract
We propose the full system of Baxter Q-functions (QQ-system) for the integrable spin chains with the symmetry of the Dr Lie algebra. We use this QQ-system to derive new Weyl-type formulas expressing transfer matrices in all symmetric and antisymmetric (fundamental) representations through r + 1 basic Q-functions. Our functional relations are consistent with the Q-operators proposed recently by one of the authors and verified explicitly on the level of operators at small finite length.
High-order conservative formulation of viscous terms for variable viscosity flows
Authors: De Vanna Francesco , Benato Alberto , Picano Francesco , Benini Ernesto 
Published: February 2021

AbstractThe work presents a general strategy to design high-order conservative co-located finite-difference approximations of viscous/diffusion terms for flows featuring extreme variations of diffusive properties. The proposed scheme becomes equivalent to central finite-difference derivatives with corresponding order in the case of uniform flow properties, while in variable viscosity/diffusion conditions it grants a strong preservation and a proper telescoping of viscous/diffusion terms. Presented tests show that standard co-located discretisation of the viscous terms is not able to describe the flow when the viscosity field experiences substantial variations, while the proposed method always reproduces the correct behaviour. Thus, the process is recommended for such flows whose viscosity field highly varies, in both laminar and turbulent conditions, relying on a more robust approximation of diffuse terms in any situation. Hence, the proposed discretisation should be used in all these cases and, for example, in large eddy simulations of turbulent wall flows where the eddy viscosity abruptly changes in the near-wall region.
Genetic Correlates of Psychological Responses to the COVID-19 Crisis in Young Adult Twins in Great Britain
Authors: Rimfeld Kaili , Malanchini Margherita , Allegrini Andrea G. , Packer Amy E. , McMillan Andrew , Ogden Rachel , Webster Louise , Shakeshaft Nicholas G. , Schofield Kerry L. , Pingault Jean-Baptiste , Stringaris Argyris , von Stumm Sophie , Plomin Robert 
Published: February 2021

AbstractWe investigated how the COVID-19 crisis and the extraordinary experience of lockdown affected young adults in England and Wales psychologically. One month after lockdown commenced (T2), we assessed 30 psychological and behavioural traits in more than 4000 twins in their mid-twenties and compared their responses to the same traits assessed in 2018 (T1). Mean changes from T1 to T2 were modest and inconsistent. Contrary to the hypothesis that major environmental changes related to COVID-19 would result in increased variance in psychological and behavioural traits, we found that the magnitude of individual differences did not change from T1 to T2. Twin analyses revealed that while genetic factors accounted for about half of the reliable variance at T1 and T2, they only accounted for ~ 15% of individual differences in change from T1 to T2, and that nonshared environmental factors played a major role in psychological and behavioural changes. Shared environmental influences had negligible impact on T1, T2 or T2 change. Genetic factors correlated on average .86 between T1 and T2 and accounted for over half of the phenotypic stability, as would be expected for a 2-year interval even without the major disruption of lockdown. We conclude that the first month of lockdown has not resulted in major psychological or attitudinal shifts in young adults, nor in major changes in the genetic and environmental origins of these traits. Genetic influences on the modest psychological and behavioural changes are likely to be the result of gene–environment correlation not interaction.
Systematic Variation in Waste Site Effects on Residential Property Values: A Meta-Regression Analysis and Benefit Transfer
Authors: Schütt Marvin 
Published: February 2021

AbstractThis article presents a meta-analysis based on 727 estimates from 83 hedonic pricing studies to provide new insights on the effects of waste sites on residential property values. Relative to previous meta-analyses on this subject, estimates are corrected for publication bias and the ability of the meta-regression model to produce reliable benefit-transfer estimates is assessed. Proximity to severely contaminated waste sites has a supremely negative impact on residential property values, whereas on average the distance from non-hazardous waste sites has no effect. Correcting for publication bias has a sizeable impact, reducing the average effect size by up to 38%. Benefit-transfer errors based on the meta-regression model are fairly large and, in line with the broader literature, outperform simple value transfer when the underlying data sample is heterogeneous.
Finite Strain Modelling for Multiphase Flow in Dual Scale Porous Media During Resin Infusion Process
Authors: Huang Ruoyu 
Published: February 2021

AbstractResin infusion is a pressure-gradient-driven composite manufacturing process in which the liquid resin is driven to flow through and fill in the void space of a porous composite preform prior to the heat treatment for resin solidification. It usually is a great challenge to design both the infusion system and the infusion process meeting the manufacturing requirements, especially for large-scale components of aircraft and wind turbine blades. Aiming at addressing the key concerns about flow fronts and air bubble entrapment, the present study proposes a modelling framework of the multiphase flow of resin and air in a dual scale porous medium, i.e. a composite preform. A finite strain formulation is discussed for the fluid–solid interaction during an infusion process. The present study bridges the gap between the microscopic observation and the macroscopic modelling by using the averaging method and first principle method, which sheds new light on the high-fidelity finite element modelling.