bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Smart Education Paradigm: Expected Outcomes and Real-Life Student Experience
Authors: Strogetskaya E. V. , Betiger I. B. 
Published: April 2021

Introduction.The article examines the transition of higher education to the paradigm of smart education. The article presents the results of a sociological study, the purpose of which was to compare the real experience of online learning of students with the expected results from the implementation of the principles of the new digital educational paradigm.Methodology and sources.The principles of the economics of higher education, the institutional tradition of the sociology of higher education, and the theory of social representations were used as a methodological framework for the study.Results and discussion.The results of monitoring the satisfaction and self-assessment of the online learning experience of students of one of the leading technical universities in Russia are presented. The authors of the article revealed the interest and generally positive attitude of students, regardless of whether or not they have an appropriate educational experience in online learning. At the same time, the question remains whether at the present stage of digitalization of higher education its transition to the principles of the smart paradigm is being carried out.Conclusion.First, there is still no sufficient data on a significant increase in the effectiveness of educational activities. It is possible to record only an increase in student satisfaction with their academic performance. Secondly, there is a problem of self-organization of the system. Finally, the degree of readiness of students who have completed online training for independent production of knowledge and solving non-standard problems is not clear. Rather, on the contrary, the more difficult the mastered professional discipline becomes, the more students need the help of a teacher.
FLIPPED CLASSROOM : PENINGKATAN KEMAMPUAN BERPIKIR KRITIS MATEMATIS DAN MOTIVASI BELAJAR PESERTA DIDIK MADRASAH TSANAWIYAH
Authors: Widyasari Shafira Fiscarina , Masykur Rubhan , Sugiharta Iip 
Published: April 2021

This study aims to improve students' mathematical critical thinking skills and learning motivation through the Flipped Classroom learning model. This research is a kind of Quasi-Experimental Design research. The population in this study were students of class VIII MTs Al Khairiyah Agom, sampling using the Cluster Random Sampling technique obtained two classes from several VIII classes at MTs Al-Khairiyah Agom. As a sample, the experimental class uses flipped classroom, while the control class is learning using the expository learning model. Analysis of the data used in this study used the MANOVA test with the R program. Based on the research analysis results, there was an effect of flipped classroom learning on improving mathematical critical thinking skills and learning motivation of students. The essential mathematical skills of thinking and learning motivation of students who use flipped classroom learning are better than the mathematical critical thinking skills of students who use expository knowledge.
Abstrak
Penelitian ini bertujuan untuk meningkatkan kemampuan berfikir kritis matematis dan motivasi belajar peserta didik melalui model pembelajaran Flipped Classroom. Penelitian ini merupakan penelitian jenis Quisi Experimental Design. Populasi pada penelitian ini yaitu peserta didik kelas VIII MTs Al Khairiyah Agom, pengambilan sampel menggunakan teknik Cluster Random Sampling didapat dua kelas dari beberapa kelas VIII di MTs Al-Khairiyah Agom. Sebagai sampel kelas eksperimen yaitu pembelajaran menggunakan flipped classroom, sedangkan kelas kontrol yaitu pembelajaran menggunakan model pembelajaran ekspositori. Analisis data yang digunakan dalam penelitian ini menggunakan uji MANOVA dengan program R. Berdasarkan hasil analisis penelitian terdapat pengaruh pembelajaran flipped classroom terhadap peningkatan kemampuan berpikir kritis matematis dan motivasi belajar peserta didik. Kemampuan berpikir kritis matematis dan motivasi belajar peserta didik yang menggunakan pembelajaran flipped classroom lebih baik dibandingkan kemampuan berpikir kritis matematis peserta didik yang menggunakan pembelajaran ekspositori.
Translation in EFL Classroom
Authors: TOÇI Arta 
Published: April 2021

Throughout much of the history of research into second language acquisition (SLA), the role of learners’ first language (L1) has been a hotly debated issue. Prodromou (2000) refers to the mother tongue as a ‘skeleton in the closet’, while Gabrielatos (2001) calls it a ‘bone of contention’. Such views are but a mere reflection of the different methodological shifts in English Language Teaching, which have brought about new and different outlooks on the role of the mother tongue. The conflict itself is taking place in academic circles rather than in classrooms, where the use of L1 is still considered unacceptable owing to the predominance of the communicative method in language teaching.

Research on the role that mother tongue has for the non-native learners of English has been conducted around the world, however none in North Macedonia. This research aims to explore some of the controversy regarding the use of the student’s first language (L1), as well as to suggest translation activities as a beneficial tool for the students of South East European University in Tetovo, North Macedonia. It also provides insights into native language interference in the process of translating from students’ mother tongue into English, and vs.
ANALISIS PENGARUH PENDAPATAN ASLI DAERAH (PAD), DANA ALOKASI UMUM (DAU), DANA ALOKASI KHUSUS (DAK) TERHADAP PERTUMBUHAN EKONOMI DAN PENGANGGURAN DI PROVINSI ACEH
Authors: Yani Rizal  , Iskandar  , Devra Wati  
Published: April 2021

Penelitian ini bertujuan untuk mengetahui pengaruh pendapatan asli daerah (PAD), dana alokasi umum (DAU), dana alokasi khusus (DAK) terhadap pertumbuhan ekonomi dan pengangguran di Provinsi Aceh, melalui pengaruh langsung dan tidak langsung. Penelitian ini menggunakan data time series dengan runtun waktu dari tahun 2008-2019. Model penelitian ini menggunakan model analisis jalur (path analyisis) dengan menggunakan aplikasi E-views versi 11. Hasil penelitian dengan tingkat signifikansi 5% menunjukkan bahwa variabel pendapatan asli daerah (X1) secara langsung berpengaruh positif dan tidak signifikan terhadap pertumbuhan ekonomi (Y1). Variabel dana alokasi umum (X2) secara langsung berpengaruh positif dan signifikan terhadap pertumbuhan ekonomi (Y1). Variabel dana alokasi khusus (X3) secara langsung berpengaruh positif dan tidak signifikan terhadap pertumbuhan ekonomi (Y1). Variabel pendapatan asli daerah (X1) dan dana alokasi umum (X2) secara langsung berpengaruh positif dan tidak signifikan terhadap pengangguran (Y2), dan variabel dana alokasi khusus (X3) secara langsung berpengaruh negatif dan signifikan terhadap pengangguran (Y2). Variabel pendapatan asli daerah (X1) dan dana alokasi umum (X2) secara tidak langsung berpengaruh positif dan tidak signifikan terhadap pengangguran (Y2) melalui pertumbuhan ekonomi (Y1), sedangkan variabel dana alokasi khusus (X3) secara tidak langsung berpengaruh positif dan signifikan terhadap pengangguran (Y2) melalui pertumbuhan ekonomi (Y1) di Provinsi Aceh.
Relationship between Nutritional Status and Development of Preschool Aged Children in the Operational Area of Puskesmas Batua Raya
Authors: Azizah Nuraeni , Darmawansyih  , Fauziah Henny 
Published: April 2021

Introduction: Development is a mental change that occurs gradually and over time, starting from simple abilities to more difficult abilities, such as attitude, behavior and intelligence. Preschool age is a golden age in which all aspects of development play an important role in aspects of further development. The study aimed to determine the relationship between nutritional status and development of preschool aged children in the operational area of ​​Puskesmas Batua Raya.
Methods: The study used a cross sectional study design with total sample of 196 respondents. Data were collected through anthropometric measurements of body weight and KPSP assessment (developmental pre-screening questionnaire) was carried out. Data analysis was performed using the chi square test.
Results: Results of the study found that children with appropriate development were higher in good nutritional status (74%) than those who were below the nutritional status (5.6%). Analysis of the two variables shows the value of p = 0.000. Statistically, there was a significant relationship between nutritional status and development of preschool children.
Conclusion: Based on the research, it may be concluded that there is a relationship between maternal knowledge and the behavior of exclusive breastfeeding in the operational area of the Sudiang Primary Health Center.
Cinderella Syndrome of Working Women in Cyber Literature
Authors: Fatimah Eva , Istiani Imas 
Published: April 2021

Abstract. Cyber literature has been academically recognized in literary studies through multiple research studies. Cyber literature is manifested in various cyberspace, both maintained individually and professionally. Writing platforms on the internet, such as Wattpad, have been widely used. They provide space for writers and engage readers to create online writing communities. One of the most popular genres found in cyber literature is romance chick-lit, in which most main characters are working women. Although most protagonists are working women who are financially independent, they still search for men who have higher positions, social levels, and financial stability. They wish that such men will find and save them, referred to by Colette Dowling as Cinderella complex. The study investigates the Cinderella complex's indications on female protagonists in two Wattpad chick lit works: 1) Furious Boss & Naughty Secretary, and 2) Ex-lovers but Married. The indications of Cinderella Complex were shown through 1) the wish to be saved, 2) the girl-child lives on, 3) the achievement gap, 4) the intimations of helplessness, and 5) the blind devotion.Keywords: Cinderella complex; cyber literature, WattpadAbstrak. Sastra cyber sudah diperhitungkan sebagai bagian dari studi sastra secara akademik melalui berbagai penelitian yang sudah dilakukan. Sastra cyber terwujud di dalam berbagai ruang cyber, baik itu dijalankan secara individual maupun profesional. Platform menulis pada internet seperti Wattpad sudah marak digunakan sebagai tempat berkarya bagi penulis serta menarik perhatian pembaca untuk menciptkana suatu komunitas menulis secara online. Salah satu genre populer pada sastra cyber adalah chicklit romantis yang mana karakter utamanya adalah wanita pekerja. Meskipun protagonis wanita merupakan wanita pekerja yang independen secara finansial, mereka masih mengharapkan pasangan yang berada di posisi, tingkat sosial dan kestabilan finansial yang lebih besar dari mereka. Studi ini bertujuan untuk mencari indikasi adanya Cinderella complex pada karakter protagonis perempuan melalui dua karya chicklit di Wattpad, yaitu: 1) Furious Boss & Naughty Secretary, dan 2) Mantan Tapi Menikah. Indikasi Cinderella complex yang ditemukan adalah 1) keinginan untuk diselamatkan, 2) gadis-kecil yang hidup di dalam diri, 3) kesenjangan prestasi, 4) tanda ketidakmampuan, dan 5) kepatuhan yang buta.Kata kunci: Cinderella complex; sastra cyber, Wattpad
Analysis of Motivational Factors of MSMEs Entrepreneurs to Be Halalpreneurs
Authors: Mumtaz Anwari  , Sri Rahayu Hijrah Hati  
Published: April 2021

This study aims to examine the motivational factors of Micro, Small and Medium Enterprises (MSMEs) entrepreneurs to become Halalpreneurs based on their religiosity, attitude (awareness of halalentrepreneurship, intrinsic motivation, effort to seek out opportunity, creativity and motivation, honesty and integrity, risk-taking attitude, relative advantage and perceived desirability), subjective norm (family support and peer influence) and perceived behavioral control (perceived feasibility, government support). Data were collected from 239 Muslim entrepreneurs who run their MSMEs. Data were then analyzed using descriptive analysis and partial least square in SmartPLS 3.0. From the result, awareness of halalpreneurship, intrinsic motivation, effort to seek out opportunity, relative advantage, perceived desirability, family support, and perceived feasibility positively are found to influence halalpreneurial propensity significantly. Meanwhile, creativity and innovation, honesty and integrity, perceived governmental support, peers influence, risk-taking attitude, and religiosity are not significant in influencing the MSMEs entrepreneur's halalpreneurial propensity.
Synthesis, Biological Evaluation, and QSAR Studies of 3-Iodochromone Derivatives as Potential Fungicides
Authors: Kaushik Parshant , Shakil Najam A. , Rana Virendra S. 
Published: April 2021

Despite the emergence of novel biotechnological and biological solutions, agrochemicals continue to play an important role in crop protection. Fungicide resistance is becoming a major problem; numerous cases of fungicide resistance have occurred worldwide in the last decade, resulting in the loss of several fungicides. The discovery of new molecules has therefore assumed critical importance in crop protection. In our quest for biologically active molecules, we herein report the synthesis of a series of twenty-one 3-Iodochromone derivatives (4a–4u), in a two-step process by condensation of 2-hydroxyacetophenone derivatives (2a–2u) with N,N-dimethylformamidedimethylacetal yielding enaminones (3a–3u), followed by cyclization with iodine to corresponding 3-iodochromones. Characterization of these compounds was done by IR, 1H NMR, 13C NMR, and LC-HRMS techniques. All synthesized compounds were screened for their fungicidal activity against Sclerotium rolfsii. Among these 6,8-Dichloro-3-iodochromone 4r was found to be most active (ED50 = 8.43 mg L−1). 2D-Quantitative Structural Activity Relationship (2D-QSAR) analysis was also performed by generating three different models viz., Multiple Linear Regression (MLR, Model 1), Principal Component Regression (PCR, Model 2), and Partial Least Squares (PLS, Model 3). Predictive power and statistical significance of these models were assessed with external and internal validation and leave one-out cross-validation was used for verification. In QSAR study, MLR (Model 1) was found to be best having correlation coefficient (r2) 0.943, cross-validated correlation coefficient (q2) 0.911 and r2pred 0.837. It was observed that DeltaEpsilonC, T_2_Cl_6, T_2_F_6, T_T_F_3, and ZCompDipole are the major descriptors which influence the fungicidal activity of 3-Iodochromone derivatives. The physicochemical parameters were estimated by the VLifeMDS 4.6 software. The QSAR study results will be helpful for structure optimization to improve the activity.
Case Report: Effective Treatment for Acute Chlorpyrifos Poisoning Complicated by a Non-ST-Segment Elevation Myocardial Infarction
Authors: Ye Changqing , Zhang Qiang , Chao Yongsheng , Yin Chun 
Published: April 2021

Background: Acute myocardial infarction (AMI) is a rare complication of acute organophosphorus pesticide poisoning. Although chlorpyrifos has been widely used as an organophosphate insecticide, a few cases of AMI complicated by chlorpyrifos poisoning have been reported thus far. Hence, a suitable treatment strategy remains to be explored.Case Presentation: Based on the clinical manifestations, medical history, results of an auxiliary examination, and serum biomarkers, a 65-year-old male farmer with complaints of nausea, vomiting, chest tightness, and pain was clearly diagnosed as having a severe chlorpyrifos self-poisoning with acute non-ST-segment elevation MI. Because the patient and his family confirmedly refused a coronary intervention, conservative treatment was used instead. It should be noted that there were some conflicts of the management for chlorpyrifos poisoning and AMI. Although rapid atropinization would contribute to the relief of muscarinic symptoms, it would also lead to an increased heart rate and myocardial oxygen consumption in AMI. Furthermore, the reduction of platelet aggregation, which is necessary for coronary recanalization of an AMI patient, is known to aggravate the gastrointestinal injury caused by poisoning. In this case, these conflicts were properly addressed, which led to an excellent effect and prognosis of the patient.Conclusions: To our knowledge, this is the first case report of acute chlorpyrifos poisoning with AMI. It is emphasized that patients with chest pain or coronary heart disease should be treated with atropine more cautiously because of the possible AMI. Moreover, proper resolution of conflicts in the management for chlorpyrifos poisoning and AMI played contributing roles in patient improvement.
Effect of Left Atrial Appendage Closure in Combination With Catheter Ablation on Left Atrial Function for Persistent Atrial Fibrillation
Authors: Yang Jing , Liu Yue , Feng Liang , Liu Mingqing , You Ling , Liu Yu , Wu Jinglan , Zhang Guangming , Geng Xue , Xie Ruiqin 
Published: April 2021

Background: A single procedure combining left atrial appendage closure (LAAC) plus catheter ablation (CA) has been proven to be safe and feasible for treating atrial fibrillation (AF). However, the influence of treatment modality on left atrial (LA) function is not thoroughly explained.Objective: We aimed to investigate the changes of LA function in persistent AF patients undergoing concomitant LAAC and CA.Methods: The study population comprised 65 patients who underwent combined AF ablation and Watchman LAAC (combined therapy group) in our center, and 65 participants of the AF simple ablation group who were matched based on sex, age, CHA2DS2-VASc score and HAS-BLED score using propensity score matching. During the 1-year follow-up period, two-dimensional echocardiography and speckle tracking echocardiography were performed to assess LA reservoir, conduit, and contractile function.Results: The combined therapy was associated with a significant improvement in the LA reservoir function with increased expansion index and strain indices, including strain and strain rate (SR) during ventricular systole. Conduit function with SR during early ventricular diastole was also improved, as was contractile function with active atrial emptying fraction and SR during atrial systole. Similarly, LA reservoir and contractile function indices all improved continuously during follow-up after catheter ablation alone. At 3 months follow-up LA reservoir and conduit function with strain indices had a tendency to improve only in the simple procedure group. At 1-year follow-up there was no significant difference in either LA volumes or strain indices between the two groups.Conclusion: Both the combined therapy group and the simple ablation group demonstrated significant improvement in LA function. Based upon the fact that LA function was improved in both groups it might be concluded that most of the effects appeared to result from ablation, not LAAC; furthermore the additional LAAC procedure did not affect the improvement of LA function after CA.
Identifying New Hybrid Insulin Peptides (HIPs) in Type 1 Diabetes
Authors: Mannering Stuart I. , Rubin Alan F. , Wang Ruike , Bhattacharjee Pushpak 
Published: April 2021

In 2016 Delong et al. discovered a new type of neoepitope formed by the fusion of two unrelated peptide fragments. Remarkably these neoepitopes, called hybrid insulin peptides, or HIPs, are recognized by pathogenic CD4+ T cells in the NOD mouse and human pancreatic islet-infiltrating T cells in people with type 1 diabetes. Current data implicates CD4+ T-cell responses to HIPs in the immune pathogenesis of human T1D. Because of their role in the immune pathogenesis of human T1D it is important to identify new HIPs that are recognized by CD4+ T cells in people at risk of, or with, T1D. A detailed knowledge of T1D-associated HIPs will allow HIPs to be used in assays to monitor changes in T cell mediated beta-cell autoimmunity. They will also provide new targets for antigen-specific therapies for T1D. However, because HIPs are formed by the fusion of two unrelated peptides there are an enormous number of potential HIPs which makes it technically challenging to identify them. Here we review the discovery of HIPs, how they form and discuss approaches to identifying new HIPs relevant to the immune pathogenesis of human type 1 diabetes.
Distinguishing Coronavirus Disease 2019 Patients From General Surgery Emergency Patients With the CIAAD Scale: Development and Validation of a Prediction Model Based on 822 Cases in China
Authors: Zhao Bangbo , Wei Yingxin , Sun Wenwu , Qin Cheng , Zhou Xingtong , Wang Zihao , Li Tianhao , Cao Hongtao , Wang Yujun , Wang Weibin 
Published: April 2021

Background: During the epidemic, surgeons cannot identify infectious acute abdomen patients with suspected coronavirus disease 2019 (COVID-19) immediately using the current widely applied methods, such as double nucleic acid detection. We aimed to develop and validate a prediction model, presented as a nomogram and scale, to identify infectious acute abdomen patients with suspected COVID-19 more effectively and efficiently.Methods: A total of 584 COVID-19 patients and 238 infectious acute abdomen patients were enrolled. The least absolute shrinkage and selection operator (LASSO) regression and multivariable logistic regression analyses were conducted to develop the prediction model. The performance of the nomogram was evaluated through calibration curves, Receiver Operating Characteristic (ROC) curves, decision curve analysis (DCA), and clinical impact curves in the training and validation cohorts. A simplified screening scale and a management algorithm were generated based on the nomogram.Results: Five potential COVID-19 prediction variables, fever, chest CT, WBC, CRP, and PCT, were selected, all independent predictors of multivariable logistic regression analysis, and the nomogram, named the COVID-19 Infectious Acute Abdomen Distinguishment (CIAAD) nomogram, was generated. The CIAAD nomogram showed good discrimination and calibration, and it was validated in the validation cohort. Decision curve analysis revealed that the CIAAD nomogram was clinically useful. The nomogram was further simplified as the CIAAD scale.Conclusion: We established an easy and effective screening model and scale for surgeons in the emergency department to use to distinguish COVID-19 patients. The algorithm based on the CIAAD scale will help surgeons more efficiently manage infectious acute abdomen patients suspected of having COVID-19.