bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of patient-reported outcome measures in primary care: applications, benefits and challenges
Authors: Brower Krista , Schmitt-Boshnick Margo , Haener Michel , Wilks Shea , Soprovich Allison 
Published: October 2021

AbstractPROMs use in primary care has expanded from simply describing patient populations to contributing to decision-making, in response to the increasingly complex, ever-changing healthcare environment. In Alberta, primary care is organized into primary care networks (PCNs), where family physicians are grouped geographically and supported by allied health professionals. PCNs implement programs and services in response to local population health needs with frequent evaluation, often incorporating PROMs for this purpose. As PCN programs and services vary greatly across Alberta, so do their use of PROMs. An area of commonality is the use of the EQ-5D-5L instrument; 29 out of 41 PCNs are registered and licensed to use the instrument. It is often administrated by paper, pre- and post-program, and in combination with other specific measures, depending on the program or target population. Some PCNs share programming and therefore outcome measurement, but often the selection, implementation (including training and administration procedures) and evaluation/reporting of PROMs are unique to the PCN. As well, data analysis is largely dependent on the size and capacity of the PCN. Using PROMs for PCN program evaluation supports clinical understanding and complements clinical outcomes. PROMs describe the population attending a program, as well as provide an element of consistency when examining trends across multiple programs or timepoints. This contributes to inquiries and decisions around program development, components, administrative features, resource allocation and delivery. Challenges of PROMs use in primary care include the absence of cohesive data capture technology. This limits data capabilities and presents difficulties with data fidelity, storage, export, and analysis. Additionally, this real-world application lacks a control arm and presents methodological challenges for comparative research purposes. Furthermore, capturing long term patient outcomes poses administrative challenges of multiple follow ups. More research is required into best reporting mechanisms to ensure the data is used to its full potential. To overcome these challenges, leadership and clinician engagement are key. As well, determining consistent PCN PROM reporting requirements will ensure data are comparable across PCNs and contribute to provincial level evaluations, further supporting the movement towards overall health system quality improvement.
Utilizing Patient Reported Outcome Measures (PROMs) in ambulatory oncology in Alberta: Digital reporting at the micro, meso and macro level
Authors: Watson Linda , Delure Andrea , Qi Siwei , Link Claire , Chmielewski Lindsi , Photitai Éclair , Smith Louise 
Published: October 2021

AbstractCancer patients experience numerous distressing symptoms and concerns across the course of their illness, which negatively influence their quality of life. Regardless of cancer type, unmanaged symptoms can lead to adverse downstream consequences. Patient Reported Outcome Measures (PROMs) can be used to inform patient care and lead to targeted symptom management but simply gathering this information does not improve outcomes for the patient. Patient generated information must be easy for the clinicians to access and interpret if it is to be used to inform care delivery in ambulatory oncology facilities. This pragmatic work responded to this need. One Canadian provincial ambulatory oncology jurisdiction implemented digital tracking of PROMs over time in the provincial Electronic Medical Record (EMR) to support full integration of PROMs into standard care workflows and processes. Due to an inability within the EMR for direct patient entry, a hybrid data-entry was designed where the patient completes a paper-based PROM in the waiting room, and after clinical review, a clinician documents this along with their clinical assessment in the EMR. Several digital dashboards were developed which report PROMs data at the micro (individual), meso (clinic) and macro (program) levels. Using PROMs routinely in these provincial practice settings has numerous benefits including enhanced patient-clinician communication, assisting with problem detection, management of symptoms, and improving outcomes for patients. There are over 60,000 unique patients represented in our PROMs database, and over 300,000 unique screening events captured. The PROMs data is now used at all levels of the provincial cancer jurisdiction to provide targeted person centred care (micro), to staff appropriately at a clinic or program level (meso), and for capacity planning for provincial programs (macro). A new provincial EMR is currently being implemented which has an associated patient portal. Based on the success of this work, integration of direct entry of PROMs by the patient prior to the appointment and an associated workflow for symptom management is underway in this jurisdiction.
Thoracic esophageal perforation by the use of Magill forceps in infant, success with non-operative treatment: case report
Authors: Bori Bata Abdel-Kémal , Gbénou Antoine Séraphin , Akodjènou Joseph , Kpossou Aboudou Raïmi , Noukpozoukou Bruno , Fiogbe Armand Michel 
Published: October 2021

Abstract
Background
Esophageal perforation is a rare surgical pathology in children. Thoracic esophageal perforation is more severe than cervical esophageal perforation. Iatrogenic cause, mainly by endoscopy, is the most common in esophageal perforation. However, perforation induced by “Magill forceps” is exceptional.

Case presentation
A systematic physical examination revealed pyrexia severe respiratory distress and right-sided pleural effusion.
We report the success of non-operative treatment applied to thoracic esophageal perforation due to Magill forceps in a 24-month-old male infant. The immediate and short-term outcomes were excellent.

Conclusions
Non-operative treatment is possible in iatrogenic perforation of thoracic esophageal in infants. This treatment delivers excellent outcome in carefully selected patients.
Investigating dizziness symptom in adult cases with Crimean-Congo hemorrhagic fever using various scales
Authors: Bora Adem , Büyüktuna Seyit Ali , Durmuş Kasım , Demirkıran Berat Baturay , Aslan Yasin , Oksüz Caner , Altuntas Emine Elif 
Published: October 2021

AbstractBackgroundThis study was to investigate the frequency of self-reported dizziness symptom in cases with Crimean-Congo hemorrhagic fever (CCHF) and the severity of dizziness, if any, by using various scales. The frequency and severity of the self-reported dizziness symptom of CCHF patients, level of disability caused by dizziness, and to what extent vestibular symptoms affected activities of daily living were assessed by various scales. The frequency and severity of the self-reported dizziness symptom of CCHF patients, level of disability caused by dizziness, and to what extent vestibular symptoms affected activities of daily living were assessed by various scales.ResultsThe frequency of dizziness in CCHF cases included in the study was 11.11% and all the cases were involved in the mild category in terms of disease severity. When the results of the scales applied to all of the cases were evaluated in general, it was seen that there was no vertigo or dizziness.ConclusionAccording to the results of the present study, we consider that multicenter studies with large series investigating pathophysiological mechanisms underlying these clinical symptoms are needed in order to evaluate dizziness symptom and to make definitive interpretations in CCHF disease.
A new method of mineral inversion based on error analysis and static response equation error: A case study of a shale gas reservoir in the Wufeng-Longmaxi Formation
Authors: Liu Weinan , Zhang Chaomo , Zhang Zhansong , Li Jun , Zhu Linqi , Hu Song , Zhou Xueqing 
Published: October 2021

The accurate quantitative calculation of mineral components is very important and basic work in formation evaluation. Using well-log data to estimate mineralogy and porosity is a mainstream method with core measurements often used. However, in shale reservoirs, there are many mineral components, such as organic matter and pyrite. In addition, the pore structure is complex, and gas exists in the pores as free state, adsorbed state, and dissolved state. These factors make the logging response characteristics more complex and thus the estimation of the mineral components more difficult. To address this problem, we have adopted a mineral inversion method based on error analysis and response equation error. Based on the error analysis of the mineral inversion method, we first establish a technique to obtain interpretation parameters and the function of the response equation error combined with the core data. Then, based on the weighted total least-squares method, we construct the objective function, and we use the improved krill herd algorithm to solve the problem. Finally, we estimate the mineral component volume. The calculated results indicate that the method can accurately determine the clay, quartz + feldspar, carbonate contents, and porosity by conventional logging data. Compared to the traditional mineral inversion method, the average relative error is reduced by 11.1%. The method has high applicability to shale reservoirs and can supply the basic parameters for formation evaluation.
Development of a Controlled Continuous Low-Dose Feeding Process
Authors: Fathollahi Sara , Kruisz Julia , Sacher Stephan , Rehrl Jakob , Escotet-Espinoza M. Sebastian , DiNunzio James , Glasser Benjamin J. , Khinast Johannes G. 
Published: October 2021

AbstractThis paper proposes a feed rate control strategy for a novel volumetric micro-feeder, which can accomplish low-dose feeding of pharmaceutical raw materials with significantly different powder properties. The developed feed-forward control strategy enables a constant feed rate with a minimum deviation from the set-point, even for materials that are typically difficult to accurately feed (e.g., due to high cohesion or low density) using conventional continuous feeders. Density variations observed during the feeding process were characterized via a displacement feed factor profile for each powder. The characterized effective displacement density profile was applied in the micro-feeder system to proactively control the feed rate by manipulating the powder displacement rate (i.e., computing the feed rate from the powder displacement rate). Based on the displacement feed factor profile, the feed rate can be predicted during the feeding process and at any feed rate set-point. Three pharmaceutically relevant materials were used for the micro-feeder evaluation: di-calcium phosphate (large-particle system, high density), croscarmellose sodium (small-particle system, medium density), and barium sulfate (very small-particle <10 μm, high density). A significant improvement in the feeding performance was achieved for all investigated materials. The feed rate deviation from the set-point and its relative standard deviation were minimal compared to operations without the control strategy.
Safety of augmentation cystoplasty in patients with bladder abnormalities undergoing renal transplantation: a systematic review
Authors: Bobby Sutojo  , Gampo Alam Irdam  
Published: October 2021

BACKGROUND Augmentation cystoplasty (AC) has been recently proposed to improve a bladder condition before or after a renal transplantation for an optimal allograft function. Until now, AC in adults with end-stage renal disease (ESRD) is uncommon and rarely practiced. This study aimed to investigate the safety of AC in patients with bladder abnormalities who required renal transplantation.
METHODS Studies of patients with ESRD and abnormal bladder who underwent AC were searched in ProQuest, PubMed, EBSCO, and Cochrane Library online databases. Only studies published in English from January 1985 to May 2020 were included. The keywords used were renal transplantation, bladder dysfunction, cystoplasty, and their synonyms. Data were extracted by two independent authors who selected, screened, and assessed the articles’ eligibility and quality. The outcomes were graft survival rate and complications of AC.
RESULTS A total of 19 articles were included. AC improved an intravesical pressure, a bladder capacity, and a compliance in patients with ESRD and bladder abnormalities, allowing patients to undergo the renal transplantation. Even though AC in patients with renal transplantation resulted in a significantly higher urinary tract infection rate than patients who underwent renal transplantation only, performing AC after renal transplantation was considered safe.
CONCLUSIONS AC was considered safe for patients with bladder abnormalities who underwent renal transplantation.
Reliability and validity of the Indonesian version of the aging males’ symptoms
Authors: Dyandra Parikesit  , Miftah Adityagama  , Widi Atmoko  , Birowo Ponco , Akmal Taher  , Nur Rasyid  
Published: October 2021

BACKGROUND Aging males’ symptoms (AMS) scale was developed to study the problems of aging males, especially related to the quality of life. Currently, there is no valid and reliable Indonesian version of the AMS scale. This study was aimed to translate and evaluate the validity and reliability of the Indonesian version of the AMS scale.
METHODS This cross-sectional study translated the existing AMS scale into Indonesian, which was tested in 40 years old males from May to August 2020. Cross-cultural validation of the AMS scale was conducted by translating the questionnaire from English to Indonesian by two independent-certified translators. The validity of the Indonesian version of the AMS scale was measured by conducting a Pearson correlation (r) analysis. The reliability of this questionnaire was tested and retested in 118 participants with a 2-week interval. In addition, Cronbach’s alpha value was measured and used as a reference. The first test was conducted in a corporate blood donor event in Matraman, East Jakarta, and the retest was conducted in Cipto Mangunkusumo Hospital.
RESULTS The Indonesian version of the AMS scale was valid and had a good internal consistency with a Cronbach’s alpha value of 0.74. The test-retest reliability showed good reliability with an r-value of 0.981. Pearson correlation test showed that all questions in the questionnaire were valid (p<0.05) and correlated positively.
CONCLUSIONS The Indonesian version of the AMS scale derived from this study is valid and has good reliability.
Precision health care strategies for older adults with diabetes in Indonesia: a Delphi consensus study
Authors: Satriya Pranata  , Shu-Fang Vivienne Wu  , Chun-Hua Chu  , Khristophorus Heri Nugroho  
Published: October 2021

BACKGROUND Studies on precision health care for older adults with diabetes in Indonesia are still limited. This study was aimed to reach the experts consensus on the suitable precision health care strategies for older adults with diabetes.
METHODS A total of 10 experts (4 physicians, 4 nurses, and 2 dietitians) agreed to participate in the 3-round interview using Delphi technique. The experts should have at least 5 years of experience in teaching or working as health professionals in a hospital.
RESULTS Consensus was reached that precision health care consisted of eight elements: self-management, interdisciplinary collaborative practice, personalized genetic or lifestyle factors, glycemic target, patient preferences, glycemic control, patient priority-directed care, and biodata- or evidence-based practice. The strategies of precision health care for diabetes were divided into seven steps: conducting brief deducting teaching; assessing self-management level and risk of cardiovascular disease; organizing a brainstorming session among patients to exchange experiences on glycemic target and specific target behavior; making a list of patients’ needs and ranking the priorities; setting a goal and writing action; doing follow-up; and reporting the goal attempts.
CONCLUSIONS The eight elements of precision health care provided the basis of precision health care strategies for diabetic older adults, which are the real and measurable strategies for precision health care implementation in clinical settings.
Magnetostrictive current sensor with high sensitivity and a large linear range for the subway
Authors: Xu Shaoyi , Peng Qiang , Xing Fangfang , Sun Junwen 
Published: October 2021

Stray current affects the safe operation of subway equipment. The stray current leakage point can be located by measuring the current of subway running track. A magnetostrictive current sensor with high sensitivity and a large linear range is proposed to monitor track current. The design of the sensor is qualitatively guided by a set of finite element method (FEM) simulations to improve the sensitivity of the sensor. However, when the sensitivity of the sensor increases, the linear range decreases. To solve this problem, a novel current sensor, to the best of our knowledge, which is composed of magnetostrictive composites, steel bars, and adjustable coils, is presented. The linear range of the sensor is expanded by adjusting the different DC bias magnetic fields generated by the adjustable coils. The results show that when the measured current is 0–500 A and 500–1000 A, the Terfenol-D (TD) mass is only 0.14 g, and the sensitivity of the sensor is 0.391 µɛ/A and 0.418 µɛ/A, respectively. The current measurement with low cost, high sensitivity, and larger linear working range is realized, which is suitable for monitoring stray current leakage points.
High-efficiency broadband polarization-independent binary fused silica gratings for large astronomical telescopes
Authors: Wang Yanan , Chen Zhiwen , Cai Maoqi , Qiu Keqiang , Liu Zhengkun , Zhu Qingfeng , Hong Yilin 
Published: October 2021

The binary fused silica gratings (BFSGs) with high diffraction efficiency are presented for large astronomical ground-based telescopes. Calculations demonstrate that the BFSGs could obtain high diffraction efficiency in a wider wavelength range and angle of incident (AOI) range compared with volume phase holographic gratings. Several gratings with a size of

60

m
m

×

60

m
m

have been fabricated by holographic lithography and reactive ion-beam etching technology. The measured peak diffraction efficiency reaches 94%, and results show that there are 130 nm wavelength bandwidth and 12° AOI bandwidth in which diffraction efficiency is higher than 70%. The stray light causes the diffraction efficiency to decrease by about 0.48%. All measurements have indicated good consistency with the simulation results.
SARS-CoV-2 viral load as a predictor for disease severity in outpatients and hospitalised patients with COVID-19: A prospective cohort study
Authors: Knudtzen Fredrikke Christie , Jensen Thøger Gorm , Lindvig Susan Olaf , Rasmussen Line Dahlerup , Madsen Lone Wulff , Hoegh Silje Vermedal , Bek-Thomsen Malene , Laursen Christian B. , Nielsen Stig Lønberg , Johansen Isik Somuncu 
Published: October 2021

Introduction
We aimed to examine if severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) cycle quantification (Cq) value, as a surrogate for SARS-CoV-2 viral load, could predict hospitalisation and disease severity in adult patients with coronavirus disease 2019 (COVID-19).

Methods
We performed a prospective cohort study of adult patients with PCR positive SARS-CoV-2 airway samples including all out-patients registered at the Department of Infectious Diseases, Odense University Hospital (OUH) March 9-March 17 2020, and all hospitalised patients at OUH March 10-April 21 2020. To identify associations between Cq-values and a) hospital admission and b) a severe outcome, logistic regression analyses were used to compute odds ratios (OR) and 95% Confidence Intervals (CI), adjusting for confounding factors (aOR).

Results
We included 87 non-hospitalised and 82 hospitalised patients. The median baseline Cq-value was 25.5 (interquartile range 22.3–29.0). We found a significant association between increasing Cq-value and hospital-admission in univariate analysis (OR 1.11, 95% CI 1.04–1.19). However, this was due to an association between time from symptom onset to testing and Cq-values, and no association was found in the adjusted analysis (aOR 1.08, 95% CI 0.94–1.23). In hospitalised patients, a significant association between lower Cq-values and higher risk of severe disease was found (aOR 0.89, 95% CI 0.81–0.98), independent of timing of testing.

Conclusions
SARS-CoV-2 PCR Cq-values in outpatients correlated with time after symptom onset, but was not a predictor of hospitalisation. However, in hospitalised patients lower Cq-values were associated with higher risk of severe disease.
“Sometimes I think my frustration is the real issue”: A qualitative study of parents’ experiences of transformation after a parenting programme
Authors: McKay Kathy , Kennedy Eilis , Young Bridget 
Published: October 2021

IntroductionParenting programmes help to alleviate conduct problems in children, but ensuring that all parents feel supported to attend, complete and learn from these programmes has proven difficult. Parents can feel overwhelmed and struggle to change their parenting. This article aims to inform the future refinement of parenting programmes by examining parents’ narratives of how programmes motivated them to change and enabled them to put changes into practice.Method and resultsForty-two parents, most of whom had attended Incredible Years group sessions, were interviewed about their views and experiences of parenting programmes that focused on positive parenting practices. Analysis of interview transcripts drew on thematic approaches. Parents perceived that parenting programmes helped them to better understand their child and themselves and to let go of anxieties surrounding their child’s behaviour. Better understanding included greater awareness of emotions and of behaviours their child could and could not control. Parents believed this awareness helped them to change the ways that they interacted with their child, which, in turn, helped them and their child to feel calmer. With greater understanding and calmness parents believed they became more able to see for themselves the changes that they could make in their parenting and everyday lives, and to feel more confident in putting these into practice.DiscussionBy supporting parents to reflect on their own and their child’s situation, parents perceived that programmes enabled them to improve interactions with their children without getting stuck in self-blame or feeling overwhelmed. Parents of children whose behaviour remained challenging believed that programmes led to beneficial changes in the way they felt about their child’s behaviours. Enhanced support for reflection by parents could potentially help more families to benefit from parenting programmes.