bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fundamentos teóricos para una estrategia de conservación y valorización turístico-recreativa de los humedales de Ecuador
Authors: Doumet Chilán Neme Yamil 
Published: May 2021

Este trabajo tiene como objetivo central identificar las fundamentaciones teóricas y bases científicas de la planificación y manejo sostenible de los humedales de Ecuador, partiendo de la situación y significación actual de sus ecosistemas y sus problemáticas socioambientales. En primer lugar, se estudian las causas y factores desencadenantes de su deterioro y pérdida de biodiversidad, como los intereses económicos particulares, la escasa sensibilidad y el desconocimiento de su importancia ambiental por parte de los gestores locales y la poca valoración social que aún tienen en muchos territorios. La metodología empleada ha partido de un enfoque cualitativo y en una revisión sistemática de la bibliografía sobre el tema a nivel internacional, así como de información de tipo técnico y documentación oficial relativa a las políticas públicas con incidencia en estos espacios protegidos. Posteriormente se define un marco teórico para el manejo integral de los humedales, considerando también la significación de las actividades turístico-recreativas como herramienta de valorización, gestión y manejo sostenible de estos espacios. Asimismo, se ha establecido una matriz de conceptualización en la que se acotan las principales definiciones y términos sobre los humedales en Ecuador. Para finalizar se analiza la clasificación de estos espacios desde la perspectiva de sus características biológicas y físicas según los lineamientos de la Secretaría de la Convención Ramsar, que establece un total de 30 categorías de humedales naturales y otras 9 de humedales artificiales.
Palabras clave: Turismo; Áreas protegidas; Humedales; Desarrollo sostenible; Marco teórico; Ecuador.
Características de la demanda potencia del destino Cuba en la nueva normalidad postcoronavirus
Authors: HERNÁNDEZ FLORES YOAN , SÁNCHEZ BORGES YENNIFER , SALDIÑA SILVERA BISMARIO , RIVES GONZÁLEZ KARLA ANANDA 
Published: May 2021

La pandemia generada por el virus SARS-CoV-2 ha provocado graves afectaciones al sector del turismo, influyendo, a gran escala, la gran incertidumbre en los visitantes internacionales a la hora de realizar viajes en el contexto de la nueva realidad. La presente investigación surge ante la necesidad de realizar estudios sobre las preferencias de los viajeros, que en una nueva “normalidad” puedan llegar al destino Cuba para de esta forma ser capaz de brindar un servicio de calidad. Por ello se propone como objetivo general caracterizar la demanda potencial al destino Cuba en la nueva normalidad. Se aplicaron los métodos análisis-síntesis e histórico-lógico como métodos teóricos, así como el análisis documental como método empírico. Como principales resultados se obtuvieron los cambios previsibles en la demanda turística hacia Cuba, relacionadas fundamentalmente, con la decisión de viaje, fecha oportuna, motivaciones, vías de obtención de información, formas de organización del viaje, duración promedio del mismo, así como con las prioridades y medidas de prevención ante el riesgo de contagio.
Palabras clave: turismo, demanda turística potencial, nueva normalidad, post Covid 19, Cuba.
Complementarity between herbaceous and woody plants in providing resources for bees in a semi-arid tropical climate: insights for conservation
Authors: Chamorro Fermín J. , Faria Christiana M.A. , Freitas Breno M. , Araújo Francisca S. 
Published: May 2021

Abstract
The distribution of floral resources in time and space varies according to vegetation strata and to the influence of precipitation and photoperiod on flowering patterns. There are scarce studies jointly investigating the spatio-temporal distribution of plant resources for bees and at the community level, which are critical for planning strategies for their conservation. Here we investigated how herbaceous and woody strata integrate to provide resources (e.g. nectar, pollen, oil) for bees inhabiting fragments of Caatinga dryforest in the northeastern Brazil. We assessed herbaceous and woody strata species composition, abundance and their floral phenodynamics for 18 months in three 0.5-ha plots. We registered bee’s plant visits and collected data on abiotic factors to examine how they correlate to flowering patterns. Bees visited approximately 80% of the plant community, composed by a variety of growth (e.g. trees, shrubs, lianas) and life (e.g. phanerophytes, chamaephytes, hemicryptophytes, and therophytes) forms. Water availability was the main variable correlated to arboreal and herbaceous flowering, but photoperiod also played a role in annual and interannual flowering patterns. Both woody (52%) and herbaceous components (48%) similarly contributed to nectar and pollen supplies, while trees were also a source of resin. Herbaceous life forms flowered sequentially during the rainy season, keeping continuous supply until the beginning of the dry season. While growth forms in the woody stratum provided resources relatively constantly throughout the year. The phenological complementarity between different life and growth forms should be considered in bee conservation strategies, aiming to optimize resource availability throughout the year.
Positive impact of perioperative oral management on the risk of surgical site infections after abdominal surgery: A multicenter retrospective analysis conducted in Japan
Authors: Shimane Tetsu , Koike Kazuyuki , Fujita Shigeyuki , Kurita Hiroshi , Isomura Emiko Tanaka , Chikazu Daichi , Kanno Naomi , Sasaki Keiichi , Hino Satoshi , Hibi Hideharu , Koyama Takahiro , Nakamura Seiji , Nomura Takeshi , Mori Yoshiyuki , Tojyo Itaru , Yamamoto Toshiro , Yamamori Iku , Aota Keiko , Tanzawa Hideki 
Published: May 2021

Abstract
Background: Postoperative surgical site infections (SSI) can be major complications, which can prolong postoperative treatment. Perioperative oral management (POM) was first covered by Japanese national health insurance system in 2012, and patients that are scheduled to undergo major surgical treatment receive dental and oral management during the perioperative period.Objectives: The purpose of the present study was to investigate the ability of POM to prevent perioperative SSI in patients undergoing abdominal surgery.Methods: The patients’ medical records were retrospectively reviewed, and the effects of POM were investigated in a multicenter analysis involving many cases. Detailed information about SSI was assessed and compared between patients with and without POM in univariate and multivariate analyses. Results: In total, the cases of 2,782 patients (1,750 males 1,032 females) were reviewed. Of these, POM was performed in 778 patients (28.0%). Univariate analyses revealed that diabetes mellitus, Eastern Cooperative Oncology Group (ECOG) performance status, the American Society of Anesthesiologists (ASA) classification, the surgical site, the preoperative Prognostic Nutritional Index score, POM, the extent of surgery, the operation time, and the amount of intraoperative blood loss were significantly associated with postoperative SSI (Chi-square or Mann-Whitney U-test, p <0.01). The multivariate analysis revealed that POM had significant preventative effects against postoperative SSI (estimate: -0.245, standard error: 0.080, p <0.01). The surgical site, the ASA classification, and the operation time were also significant and independent clinical predictors of SSI.Conclusion: This study suggests that POM helps to prevent SSI in patients that undergo abdominal surgery.
Removal of methylene blue from aqueous solution by mesoporous silicalite-1 synthetized using carboxymethyl cellulose as template
Authors: Radoor Sabarish , Karayil Jasila , Jayakumar Aswathy , Shivanna Jyothi Mannekote , Parameswaranpillai Jyotishkumar , Siengchin Suchart 
Published: May 2021

Abstract
In the present work, we have developed a mesoporous silicalite-1 using CMC as a template for the removal of MB from aqueous solution. The synthesized silicalite-1 were characterised using scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), Energy-dispersive X-ray spectroscopy (EDX) and N2 adsorption-desorption isotherm (BET). XRD and FTIR analysis confirmed the formation of crystallinity and development of MFI structure in the mesoporous silicalite-1. The adsorption of MB dye on mesoporous silicalite-1 was conducted by batch adsorption method. The effect of various parameters such as adsorbent dosage, initial dye concentration, contact time and temperature on the dye uptake ability of silicalite-1 was investigated. The operating parameters for the maximum adsorption are silicalite-1 dosage (0.1 wt%), contact time (240 min), initial dye concentration (10 ppm) and temperature (30℃). The MB dye removal onto mesoporous silicalite-1 followed pseudo-second-order kinetic and Freundlich isotherm. The silicalite-1 exhibits 86% removal efficiency even after six adsorption-desorption cycle. Therefore, the developed mesoporous silicalite-1 is an effective eco-friendly adsorbent for MB dye removal from aqueous environment.
Optomechanical Synchronization across Multi-Octaves Frequency Spans
Authors: Rodrigues Caique , Kersul Cauê , Primo André , Lipson Michal , Alegre Thiago , Wiederhecker Gustavo 
Published: May 2021

Abstract
Experimental exploration of synchronization in scalable oscillator micro systems has unfolded a deeper understanding of networks, collective phenomena, and signal processing. Cavity optomechanical devices have played an important role in this scenario, with the perspective of bridging optical and radio frequencies through nonlinear classical and quantum synchronization concepts. In its simplest form, synchronization occurs when an oscillator is entrained by a signal nearby the oscillator's tone, and becomes increasingly challenging as the frequency detuning increases. Here, we experimentally demonstrate entrainment of a silicon-nitride optomechanical oscillator driven several octaves away from its 32 MHz fundamental frequency. Exploring this effect, we perform a 4:1 frequency division from 128 MHz to 32 MHz. Further developments could harness these effects towards frequency synthesizers, phase-sensitive amplification and nonlinear sensing.
Traditional Chinese Medicine Drynariae Rhizoma and Cuscuta Chinensis Suppress Osteoarthritis by Quercetin-AKT1 and Luteolin-IL6/VEGFA Direct Binding
Authors: Huang Xin-Zhou , Chen Hui , Wang Yu-Ming , Zhang Xi-He , Liu Ke-Bin , Huang Kui , Xin Hongwu 
Published: May 2021

Abstract
Background: Drynaria Fortunei and Cuscuta Chinensis are among the most used traditional Chinese medicine herbal prescriptions and have a significant therapeutic effect on osteoarthritis. However, the purpose of this study intends to elaborate the molecular mechanism of action through network pharmacology. The active ingredients of TCM and the potential targets for the treatment of osteoarthritis were selected through the TCMSP, OMIM and Genecards. Results: The 27 components and 85/117 targets of Drynaria Fortunei and/or Cuscuta Chinensis were identified for osteoarthritis. Pharmacological and PPI network analysis identified top 3 active components (kaempferol, luteolin, and quercetin) and core proteins (IL6, AKT1, and VEGFA). GO and KEGG analysis identified the top 3 functions (cytokine and cell/nuclear receptor) and pathways (PI3K-Akt, TNF and IL-17). Molecular docking showed strong binding ability between quercetin-AKT1 and luteolin-IL6/VEGFA. Interaction analysis mapped the quercetin-AKT1 and luteolin-IL6/VEGFA binding to specific hydrogen and hydrophobic bonds. Conclusions: The main active components, common target proteins, functional activities, and signaling pathways of TCM Drynaria Fortunei and Cuscuta Chinensis for the treatment of osteoarthritis were identified by Network pharmacology. We found, for the first time, that drynariae rhizoma and cuscuta chinensis suppress osteoarthritis by quercetin-AKT1/IL6 and luteolin-VEGFA direct binding. Our findings have significant implication for our understanding of the molecular mechanism of action in the treatment of osteoarthritis and future development of osteoarthritis treatment using quercetin and luteolin.
Safety of 0.5% hydrogen peroxide mist used in the disinfection gateway for COVID-19
Authors: Mohanan Parayanthala Valappil , Sangeetha Vijayan , Sabareeswaran Arumugham , Muraleedharan Vayalappil , Jithin Krishnan , Vandana Unnikrishnan , Varsha Sheela Bhasi 
Published: May 2021

Abstract
Hydrogen peroxide (H2O2) is a reactive chemical used in a wide range of applications. Most importantly, it is used for sterilization process in health care environment. In the present study, safety assessment of 0.5% of H2O2or its mist intended to be used in the disinfection gateway for Covid-19 was evaluated. Skin irritation and repeated dose inhalation toxicity studies were carried out in rabbits and rats respectively. Skin irritation study revealed no observable oedema and erythema in rabbits after tropical application of 0.5% H2O2. Wistar rats (both male and female) were exposed (whole body exposure) to0.5% of H2O2 mist, at a concentration of 11.022 (low dose-2 min exposure), 22.044 (medium dose-4 min exposure) and 55.11mg/kg (high dose/high doe recovery-10 min exposure) body weight, daily for seven days. Rats in the high dose recovery group (55.11mg/kg-10 min exposure) were kept for another 7 days without any exposure. A toxicological evaluation was done based on general health parameters, haematology, serum biochemistry, gross necropsy and histopathological data. The results of the study indicated that there was no skin irritation potential induced on exposure of 0.5% of H2O2to rabbits. Similarly, the inhalation toxicity of 0.5% of H2O2 mist, imparts no evidence of haematological, biochemical, gross pathology or histopathological abnormalities in rats. Further, at the laboratory condition stimulated, the NOEL was found to be 55.11mg/kg body weight. Hence, the present study concluded that 0.5% H2O2 or its mist used in the disinfection gateway for COVID-19, failed to induce any skin irritation in rabbits or inhalation toxicity in rats.
Inter-Provincial Responsibility Allocation of Carbon Emission in China to Coordinate Regional Development
Authors: Wang Feng , Ge Xing 
Published: May 2021

Abstract
To establish the carbon emission trading scheme and achieve the carbon emission reduction goals in China, it is critical to allocate the carbon emission allowance (CEA). Using the entropy method and the modified fixed cost allocation model (MFCAM), we calculated the CEA and the carbon emission intensity (CEI) reduction targets of 30 Chinese provinces in 2030, and further classified China’s provinces, from four principles (equity-efficiency-feasibility-sustainability) and three dimensions (economy-society-environment). The results are shown as follows. First, we calculated China's CEA in 2030 is 17567.9 Mt. Second, on the whole, China's southern provinces have higher CEA than northern ones. Eastern China has a larger final CEA than western China and central China. Third, Guangdong has the largest final CEA, due to its large population, developed economy, and high energy utilization efficiency. Fourth, in the future, provinces such as Guizhou, Inner Mongolia, Ningxia, Xinjiang, Shaanxi, and Shanxi will take on greater responsibility for carbon emission reduction, while provinces such as Tianjin, Qinghai, Guangxi, and Beijing will be able to sell carbon emission allowances to other provinces.
Mechanisms Controlling the Dissolved Load, Chemical Weathering and CO2 Consumption Rates of Cauvery River, South India: Role of Secondary Soil Minerals
Authors: Upendra B. , Ciba M. , Aiswarya A. , Dev V. Vinu , Sreeniva G. , Krishnan K. Anoop 
Published: May 2021

Abstract
Hydrochemical assessment of the Cauvery River Basin (CRB), an east flowing Western Ghats (WG) river is carried out to understand the dissolved load sources and controlling mechanisms along with quantification of source-wise input to the dissolved load. Silicate weathering rates (SWR) and associated CO2 consumption rates (CCR) are evaluated on account of silicate basement of CRB comprising of granulites and supracrustal rocks. The source-wise solute load contributions estimated using the chemical mass balance model signify that 68% of total load is from chemical weathering followed by 18.5% and 13.5% from anthropogenic and atmospheric inputs respectively, implying that chemical weathering is the major solute load controlling mechanism for CRB. The intensity of silicate chemical weathering occurring in the CRB is measured by index (Re) and found to be > 3, suggesting an incomplete weathering of drainage rocks (primary minerals) resulting in formation of soils comprising of secondary minerals including oxides, alumino-silicates and clay minerals (smectite, kaolinite and montmorillonite). Detailed understanding of chemical weathering mechanisms is carried out using Ca/Na and Mg/Na elemental ratios of different end-members including primary minerals from rocks and secondary minerals from soils. The Na-normalized mixing diagram reveals that chemical weathering of secondary minerals is dominating and the solute load contribution to the total dissolved load is significantly higher from secondary minerals (35.5%) than primary minerals (23.5%). The SWR and associated CCR are estimated to be 13 t.km-2.y-1 and 3.3 × 105 mole.km-2.y-1 respectively at outlet (Musiri) of the CRB. Results also indicate that SWR of the east flowing WG river, Cauvery are several times (~4) lower than the average SWR of west flowing WG rivers even though the associated CCR are comparable for both river systems.
Opportunities for winter prescribed burning in mixed conifer plantations of the Sierra Nevada
Authors: York Robert , Levine Jacob , Russell Kane , Restaino Joseph 
Published: May 2021

Abstract
Background

Young, planted forests are particularly vulnerable to wildfire. High severity effects in planted forests translate to the loss of previous reforestation investments and the loss of future ecosystem service gains. We conducted prescribed burns in three ~ 35 year-old mixed conifer plantations during February in order to demonstrate the effectiveness of winter burning, which is not common in the Sierra Nevada, California.
Results

On average, 59% of fine fuels were consumed and the fires reduced shrub cover by 94%. The average percent of crown volume that was damaged was 25%, with no mortality observed in overstory trees one year following the fires. A plot-level analysis of the factors of fire effects did not find strong predictors of fuel consumption. Shrub cover was reduced dramatically, regardless of the specific structure that existed in plots. We found a positive relationship between crown damage and the two variables of Pinus ponderosa relative basal area and shrub cover. But these were not particularly strong predictors. An analysis of the weather conditions that have occurred at this site over the past 20 years indicated that there has consistently been opportunities to conduct winter burns. Windows of time are short, typically one or two days, and may occur at any time during the winter season.
Conclusions

This study demonstrates that winter burning can be an important piece of broader strategies to reduce wildfire severity in the Sierra Nevada. Preparing forest structures so that they can be feasible to burn and also preparing burn programs so that they can be nimble enough to burn opportunistically during short windows during the winter are key strategies.
Atomic Charges, Surface Electrostatic Potential Analysis, and Bond Order Analysis on Nitriles and Isocyanides
Authors: Zhao Yanyun , Cheng Xueli 
Published: May 2021

Abstract
Isocyanide-nitrile rearrangement has long been a continuing and interesting topic. A series of nitriles and isocyanides with the substituents of R=-AlH2, -BeH, -BH2, -C ≡ CH, -CF3, -CH3, -Cl, -C ≡ N, -COOH, -F, -H, Li, -MgH, -Na, -NH2, -NO2, -OH, -PH2, -SH, -SiH3, -CH = CH2 were investigated systematically based on full optimization at B3LYP-D3(BJ)/def2-QZVP level, and the isomerization energies from R-C ≡ N to :C = N-R were estimated. The substituent effect and bonding characters were analyzed by surface ESP colored van der Waals surfaces in conjunction with the global and local electrostatic extrema, the population analyses in terms of Hirshfeld and ADCH atomic charges, and bond order analyses via Laplacian and fuzzy bond orders.
Bionic Innovative Design of Pipeline Disinfection Robot Based on Biological Text Information
Authors: Chen Liang , Zhang Huo , Liu Xiao-Min , Fan De-Hua 
Published: May 2021

Abstract
The traditional bionic innovative design method relies too much on the designer's own experience and inspiration, and the design method could be limited by designer’s own thinking. This paper presents a new bionic design method, proposing one kind of special model for the engineering design problem, through obtaining biological text information, after processing and storage in the database, combined with engineering design problems, obtains the corresponding bionic design prototype, and generates the bionic design scheme through bio-engineering mapping. This design method can effectively avoid trapping designers into their own thinking, and this method is helpful for the generation of innovative design scheme. Finally, the meta design of innovative pipeline disinfection robot is shown as an example to verify the feasibility of the method proposed in this paper.
Autoinflammation Leading to Autoimmunity in Adult Onset Still’s Disease, More Than Simple Coincidence?
Authors: Valor-Méndez Larissa , Manger Bernhard , Cavallaro Alexander , Achenbach Stephan , Schett Georg , Rech Jürgen 
Published: May 2021

Abstract
Background: Adult onset Still’s disease (AOSD) should be considered in the differential diagnosis of patients with endocarditis, with or without a cardiac decompensation. Case presentation: We report the case of a 68-year-old Caucasian male diagnosed with AOSD after an initial acute manifestation of endocarditis with severe aortic acute manifestation of endocarditis with severe aortic insufficiency. The histological findings revealed Libman-Sacks endocarditis. He was treated with the IL-1 receptor inhibitor anakinra. Two years later the patient developed a symptomatic dilated cardiomyopathy with reduced ejection fraction (23.5%) and functional anti-beta-1-adrenergic receptor antibodies, which was initially treated with plasmapheresis; anakinra was maintained. While his AOSD symptoms responded well, our patient presented with recurrent arthritis in multiple joints, dual energy-CT showed urate deposition compatible with a gouty arthropathy. Over seven years, he presented with recurrent episodes of arthritis and the adjustment of dosages of colchicine and febuxostat was needed. In 2018, our patient died due to a deterioration of his underlying cardiac disease. Conclusions: Only two cases with initial endocarditis prior to AOSD diagnosis have been published and we are not aware of any other cases reporting -β1AR-Ab development with DCM and gout in the setting of AOSD treated with anakinra.