bluuebunny/crossref_metadata_2025_split huggingface dataset:
Audit of the provision of nutritional support to mechanically ventilated dogs and cats
Authors: Greensmith Thomas D. , Chan Daniel L. 
Published: March 2021

AbstractObjectivesTo evaluate the use of enteral and parenteral nutrition in a population of mechanically ventilated cats and dogs, identify factors associated with implementation of nutrition, and assess the frequency of nutritional support within 72 hours of absent caloric intake.DesignRetrospective, single‐center audit from June 2013 to June 2016.SettingICU of a veterinary university teaching hospital.AnimalsFifty‐eight animals (50 dogs, 8 cats) that underwent mechanical ventilation for ≥6 hours with complete medical records.InterventionsNone.Measurements and Main ResultsData collected included nutritional provision, time to initiation of nutrition, period of absent caloric intake, percentage of caloric intake obtained, and possible factors contributing to the delay or failure to implement nutrition. Thirty‐one percent of patients (dogs 16/50, 32%; cats 2/8, 25%) received nutritional support during mechanical ventilation with all but 2 dogs receiving parenteral nutrition. Of those patients that did not receive nutrition (dogs 34/50, 68%; cats 6/8, 75%), documented contraindications or notations within the medical record for its omission were present in 16 of 34 dogs (47%) and 4 of 6 cats (66.7%). Thirteen animals (11 dogs, 2 cats) had >72 hours of absent caloric intake with only a small number of these receiving nutrition (dogs 4/11, 36.4%; cats 0/2, 0%).ConclusionsOnly 18 of 58 (31%) mechanically ventilated dogs and cats at our institution received nutritional support, and the majority of these were fed parenterally (16/18, 88.9%). For animals that did not receive nutrition, there was no clear reason for its absence in many cases. Animals with absent caloric intake >72 hours had poor implementation of nutritional support in contrast to current guidelines. A repeat audit after implementing changes to institutional protocols for nutritional provision is warranted to assess the impact on morbidity and mortality.
Computational Simulation and Analysis of Major Control Parameters of Time-Dependent Photovoltaic/Thermal Collectors
Authors: Shi Jimeng , Lin Cheng-Xian 
Published: March 2021

Abstract
In order to improve the transient performance of photovoltaic/thermal (PV/T) collectors, this paper first developed and validated an improved computational thermal model to investigate the effects of the major control parameters on the thermal performance of PV/T collectors, including inlet water temperature and inlet water flowrate. Second, a computational electrical model of PV/T system, coupled with the thermal model, was also introduced to elaborate the relationship of voltage, current, and power of a PV module (MSX60 polycrystalline solar cell) used in an experiment in the literature. The thermal and electrical models were solved simultaneously to predict the transient energy conversion efficiencies of the PV/T system. Simulation results were found to agree with the experimental data very well. The effects of the time-steps from 1 h to 1 min, which is close to real-time, were reported at various conditions. It was found that both thermal and electrical efficiencies are fluctuating with time. There is an optimal water flow rate at which the efficiencies are at the maximum. Suggestions to improve the efficiency of PV/T system were discussed.
Dynamic Modeling of the Double-Nut Planetary Roller Screw Mechanism Considering Elastic Deformations
Authors: Fu Xiaojun , Liu Geng , Li Xin , Ma Shangjun , Qiao Guan 
Published: March 2021

Abstract
With the rising application of double-nut planetary roller screw mechanism (PRSM) into industry, increasing comprehensive studies are required to identify the interactions among motion, forces and deformations of the mechanism. A dynamic model of the double-nut PRSM with considering elastic deformations is proposed in this article. As preloads, inertial forces and elastic deformations have a great influence on the load distribution among threads, the double-nut PRSM is discretized into a spring–mass system. An adjacency matrix is introduced, which relates the elastic displacements of nodes and the deformations of elements in the spring–mass system. Then, the compressive force acting on the spacer is derived and the equations of load distribution are given. Considering both the equilibrium of forces and the compatibility of deformations, nonlinear equations of motion for the double-nut PRSM are developed. The effectiveness of the proposed model is verified by comparing dynamic characteristics and the load distribution among threads with those from the previously published models. Then, the dynamic analysis of a double-nut PRSM is carried out, when the rotational speed of the screw and the external force acting on the nut #2 are changed periodically. The results show that if the external force is increased, the preload of the nut #1 is decreased and that of the nut #2 is increased. Although the nominal radii of rollers are the same, the maximum contact force acting on the roller #2 is much larger than that of the roller #1.
North China craton: The conjugate margin for northwestern Laurentia in Rodinia
Authors: Ding Jikai , Zhang Shihong , Evans David A.D. , Yang Tianshui , Li Haiyan , Wu Huaichun , Chen Jianping 
Published: March 2021

Abstract
In the Rodinia supercontinent, Laurentia is placed at the center because it was flanked by late Neoproterozoic rifted margins; however, the conjugate margin for western Laurentia is still enigmatic. In this study, new paleomagnetic results have been obtained from 15 ca. 775 Ma mafic dikes in eastern Hebei Province, North China craton (NCC). Stepwise thermal demagnetization revealed a high-temperature component, directed northeast or southwest with shallow inclinations, with unblocking temperatures of as high as 580 °C. Rock magnetism suggests the component is carried by single-domain and pseudo-single-domain magnetite grains. Its primary origin is supported by a positive reversal test and regional remanence direction correlation test, and the paleomagnetic pole (29.0°S, 64.7°E, A95 = 5.4°) is not similar to any published younger poles of the NCC. Matching the late Mesoproterozoic to early Neoproterozoic (ca. 1110–775 Ma) apparent polar wander paths of the NCC and Laurentia suggests that the NCC could have been the conjugate margin for northwestern Laurentia in Rodinia, rather than sitting off the northeast coast of the main Rodinian landmass. Geological data indicate that breakup of the NCC and Laurentia occurred between ca. 775 and 720 Ma.
Archean geodynamics: Ephemeral supercontinents or long-lived supercratons
Authors: Liu Yebo , Mitchell Ross N. , Li Zheng-Xiang , Kirscher Uwe , Pisarevsky Sergei A. , Wang Chong 
Published: March 2021

Abstract
Many Archean cratons exhibit Paleoproterozoic rifted margins, implying they were pieces of some ancestral landmass(es). The idea that such an ancient continental assembly represents an Archean supercontinent has been proposed but remains to be justified. Starkly contrasting geological records between different clans of cratons have inspired an alternative hypothesis where cratons were clustered in multiple, separate “supercratons.” A new ca. 2.62 Ga paleomagnetic pole from the Yilgarn craton of Australia is compatible with either two successive but ephemeral supercontinents or two long-lived supercratons across the Archean-Proterozoic transition. Neither interpretation supports the existence of a single, long-lived supercontinent, suggesting that Archean geodynamics were fundamentally different from subsequent times (Proterozoic to present), which were influenced largely by supercontinent cycles.
Light Curves of Type Ia Supernovae
Authors: Lyutykh A. V. , Pruzhinskaya M. V. , Blinnikov S. I. 
Published: March 2021

Abstract
We have studied the light curves of type Ia supernovae (SNe Ia) and the physical parameters inferred from them. We have constructed both analytical and numerical light curves of SNe Ia. Using an empirical relation between the SN luminosity and light-curve parameters, we have managed to impose constraints on the hydrodynamic solutions obtained by the STELLA code and to produce a sample of models that describe the observational properties of real SNe maximally accurately. With this sample we have established a relationship between the opacity in SN Ia ejecta and the parameters being determined directly from observations. The method has been tested on two classical SNe Ia as an example: 2011fe and 2012fr. The presented approach allows the opacity to be found without resorting to time-consuming computations.
Temporal variations in the severity of COVID-19 illness by race and ethnicity
Authors: Ebinger Joseph E , Driver Matthew , Ji Hongwei , Claggett Brian , Wu Min , Luong Eric , Sun Nancy , Botting Patrick , Kim Elizabeth H , Hoang Amy , Nguyen Trevor Trung , Diaz Jacqueline , Park Eunice , Davis Tod , Hussain Shehnaz , Cheng Susan , Figueiredo Jane C 
Published: March 2021

IntroductionEarly reports highlighted racial/ethnic disparities in the severity of COVID-19 seen across the USA; the extent to which these disparities have persisted over time remains unclear. Our research objective was to understand temporal trends in racial/ethnic variation in severity of COVID-19 illness presenting over time.MethodsWe conducted a retrospective cohort analysis using longitudinal data from Cedars-Sinai Medical Center, a high-volume health system in Southern California. We studied patients admitted to the hospital with COVID-19 illness from 4 March 2020 through 5 December 2020. Our primary outcome was COVID-19 severity of illness among hospitalised patients, assessed by racial/ethnic group status. We defined overall illness severity as an ordinal outcome: hospitalisation but no intensive care unit (ICU) admission; admission to the ICU but no intubation; and intubation or death.ResultsA total of 1584 patients with COVID-19 with available demographic and clinical data were included. Hispanic/Latinx compared with non-Hispanic white patients had higher odds of experiencing more severe illness among hospitalised patients (OR 2.28, 95% CI 1.62 to 3.22) and this disparity persisted over time. During the initial 2 months of the pandemic, non-Hispanic blacks were more likely to suffer severe illness than non-Hispanic whites (OR 2.02, 95% CI 1.07 to 3.78); this disparity improved by May, only to return later in the pandemic.ConclusionIn our patient sample, the severity of observed COVID-19 illness declined steadily over time, but these clinical improvements were not seen evenly across racial/ethnic groups; greater illness severity continues to be experienced among Hispanic/Latinx patients.
Self-reported sick leave following a brief preventive intervention on work-related stress: a randomised controlled trial in primary health care
Authors: Hultén Anna-Maria , Bjerkeli Pernilla , Holmgren Kristina 
Published: March 2021

ObjectivesTo evaluate the effectiveness of a brief intervention about early identification of work-related stress combined with feedback at consultation with a general practitioner (GP) on the number of self-reported sick leave days.DesignRandomised controlled trial. Prospective analyses of self-reported sick leave data collected between November 2015 and January 2017.SettingSeven primary healthcare centres in western Sweden.ParticipantsThe study included 271 employed, non-sick-listed patients aged 18–64 years seeking care for mental and/or physical health complaints. Of these, 132 patients were allocated to intervention and 139 patients to control.InterventionsThe intervention group received a brief intervention about work-related stress, including training for GPs, screening of patients’ work-related stress, feedback to patients on screening results and discussion of measures at GP consultation. The control group received treatment as usual.Outcome measuresThe number of self-reported gross sick leave days and the number of self-reported net sick leave days, thereby also considering part-time sick leave.ResultsAt 6 months’ follow-up, 220/271 (81%) participants were assessed, while at 12 months’ follow-up, 241/271 (89%) participants were assessed. At 6-month follow-up, 59/105 (56%) in the intervention group and 61/115 (53%) in the control group reported no sick leave. At 12-month follow-up, the corresponding numbers were 61/119 (51%) and 57/122 (47%), respectively. There were no statistically significant differences between the intervention group and the control group in the median number of self-reported gross sick leave days and the median number of self-reported net sick leave days.ConclusionsThe brief intervention showed no effect on the numbers of self-reported sick leave days for patients seeking care at the primary healthcare centres. Other actions and new types of interventions need to be explored to address patients’ perceiving of ill health due to work-related stress.Trial registration numberNCT02480855.
High TG/HDL ratio suggests a higher risk of metabolic syndrome among an elderly Chinese population: a cross-sectional study
Authors: Nie Guqiao , Hou Shukai , Zhang Meng , Peng Wen 
Published: March 2021

ObjectivesTo investigate the relationship between triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio and metabolic syndrome in the elderly population of China, and to determine the best critical value of TG/HDL-C in higher risk of metabolic syndrome in this population.DesignCross-sectional study.SettingOur study was conducted in a community physical examination centre in Wuhan, China between 1 January 2016 and 31 December 2016.ParticipantsThe physical examination data from 1267 elderly people (aged over 65 years) in the community were analysed in this study. The average age of the study participants was 71.64±5.605 years.Primary outcome measuresCorrelation between the TG/HDL-C ratio and metabolic syndrome; the optimum cut-off of the TG/HDL-C ratio for the prediction of metabolic syndrome.ResultsThe TG/HDL-C ratio showed a significant positive correlation with metabolic syndrome (r=0.420, p<0.001) in the elderly Chinese population. Binary logistic regression analysis showed that the TG/HDL-C ratio was an independent risk factor for metabolic syndrome (OR=3.07 (95% CI: 2.402 to 3.924), p<0.001) after adjusting for blood pressure, blood glucose, age, sex and body mass index. The receiver operating characteristic curves of TG/HDL-C ratio and metabolic syndrome showed that in the elderly population, a TG/HDL-C ratio of 1.49 can be used as the critical value for a higher risk of metabolic syndrome. At this value, the specificity and sensitivity of the measure were optimal (80.8% and 72.4%, respectively).ConclusionIn this study, we found a significant correlation between TG/HDL-C ratio and metabolic syndrome. And high TG/HDL ratio suggests a higher risk of metabolic syndrome among an elderly Chinese population.
Perspectives of paediatric hospital staff on factors influencing the sustainability and spread of a safety quality improvement programme
Authors: Lachman Peter , Gondek Dawid , Edbrooke-Childs Julian , Deighton Jessica , Stapley Emily 
Published: March 2021

ObjectiveSituation Awareness For Everyone (SAFE) is a quality improvement programme aiming to improve situation awareness in paediatric clinical teams. The aim of our study was to examine hospital staff perceptions of the facilitators and barriers/challenges to the sustaining and subsequent spread of the huddle, the key intervention of the SAFE programme.SettingInterviews were held on two wards in two children hospitals and on two children wards in two district general hospitals.MethodSemistructured interviews were conducted with 23 staff members from four National Health Service paediatric wards. A deductive thematic analysis was conducted, drawing on an existing framework, which groups the factors influencing programme sustainability into four categories: innovation, leadership, process and context.Participants23 staff in two children’s hospitals and two children’s wards across four UK hospitals, comprising of nurses and doctors, administration or housekeeping staff, ward managers and matrons, and allied professionals.Primary outcomesUnderstanding factors contributing to the sustaining and spread of a quality improvement intervention.ResultsPerceptions of the benefits, purpose and fit of the huddle, team commitment, sharing learning, adaptation of the method and senior leadership were identified as facilitators. High staff turnover, large multiple specialty medical staff teams, lack of senior leadership and dislike of change were identified as barriers/challenges.ConclusionsSustaining and spreading quality improvement interventions in a complex clinical setting requires understanding of the interplay between the actual innovation and existing leadership, process and contextual factors. These must be considered at the planning stage of an innovation to maximise the potential for sustainability and spread to other settings.
Anticipated responses to a hypothetical minimum price for cigarettes and roll-your-own tobacco: an online cross-sectional survey with cigarette smokers and ex-smokers in the UK
Authors: Critchlow Nathan , Moodie Crawford , Best Catherine , Stead Martine 
Published: March 2021

ObjectivesAs tobacco companies can circumvent tax increases, a minimum retail price per-cigarette/per-gram of roll-your-own tobacco presents an additional mechanism for governments to reduce smoking. We examined (1) anticipated responses to a hypothetical minimum price-per-cigarette/per-gram among smokers in the UK; (2) what demographic and smoker characteristics are associated with anticipated responses; and (3) whether minimum pricing may help ex-smokers stay quit.DesignCross-sectional survey (May–July 2019).SettingUK.ParticipantsAdult cigarette smokers (n=2412) and ex-smokers (n=700).Main outcome measurementsAnticipated responses to a hypothetical minimum price of £10.00 for 20 cigarettes (£0.50 per-cigarette) and £13.50 for 30 grams of roll-your-own tobacco (£0.45 per-gram); approximately £0.10 per-cigarette/per-gram increases on the cheapest prices in leading UK supermarkets (January 2019). Smokers were presented with ten options (eg, ‘Try to quit’) and asked which they would do (Yes/No) and then which they would most likely do. Ex-smokers were asked to what extent the minimum prices would help them stay quit (A lot vs Lesser agreement).ResultsAmong smokers, 55.6% said they would most likely smoke the same amount, 10.7% they would smoke less, 9.5% they would try to quit and 5.8% they would use e-cigarettes more often. Anticipated reactions were associated with demography and smoker characteristics, for example, C2DE (lower social grade) smokers were less likely than ABC1 (higher social grade) smokers to say they would smoke the same as they do now (ORAdj=0.74, 95% CI 0.62 to 0.88). Among ex-smokers, 38.5% said the minimum prices would help them stay quit ‘A lot’, more so among C2DE than ABC1 participants (ORAdj=1.80, 95% CI 1.30 to 2.49).ConclusionsIn response to a hypothetical minimum price for cigarettes and roll-your-own tobacco, approximately a fifth of smokers in the UK indicated they would smoke less or quit and almost two-fifths of ex-smokers indicated the prices would help them stay quit.
Videogame intervention to increase advance care planning conversations by hospitalists with older adults: study protocol for a stepped-wedge clinical trial
Authors: Mohan D , O"Malley A James , Chelen Julia , MacMartin Meredith , Murphy Megan , Rudolph Mark , Barnato Amber 
Published: March 2021

IntroductionFewer than half of all people in the USA have a documented advance care plan (ACP). Hospitalisation offers an opportunity for physicians to initiate ACP conversations. Despite expert recommendations, hospital-based physicians (hospitalists) do not routinely engage in these conversations, reserving them for the critically ill.The objective of this study is to test the effect of a novel behavioural intervention on the incidence of ACP conversations by hospitalists practicing at a stratified random sample of hospitals drawn from 220 US acute care hospitals staffed by a large, nationwide acute care physician practice with an ongoing ACP quality improvement initiative.Methods and analysisWe developedHopewell Hospitalist, a theory-based adventure video game, to modify physicians" attitudes towards ACP conversations and to increase their motivation for engaging in them. The planned study is a pragmatic stepped-wedge crossover phase III trial, testing the efficacy ofHopewell Hospitalistfor increasing ACP conversations. We will randomise 40 hospitals to the month (step) in which they receive the intervention. We aim to recruit 30 hospitalists from up to eight hospitals each step to complete the intervention, playingHopewell Hospitalistfor at least 2 hours. The primary outcome is ACP billing for patients aged 65 and older managed by participating hospitalists. We hypothesise that the intervention will increase ACP billing in the quarter after dissemination, and have 80% power to detect a 1% absolute increase and 99% power to detect a 3.5% absolute increase.Ethics and disseminationDartmouth’s Committee for the Protection of Human Subjects has approved the study protocol, which is registered on clinicaltrials.gov. We will disseminate the results through manuscripts and the trials website.Hopewell Hospitalistwill be made available on the iOS Application Store for download, free of cost, at the conclusion of the trial.Trial registration numberNCT04557930.
Measuring frailty in younger populations: a rapid review of evidence
Authors: Spiers Gemma F , Kunonga Tafadzwa Patience , Hall Alex , Beyer Fiona , Boulton Elisabeth , Parker Stuart , Bower Peter , Craig Dawn , Todd Chris , Hanratty Barbara 
Published: March 2021

ObjectivesFrailty is typically assessed in older populations. Identifying frailty in adults aged under 60 years may also have value, if it supports the delivery of timely care. We sought to identify how frailty is measured in younger populations, including evidence of the impact on patient outcomes and care.DesignA rapid review of primary studies was conducted.Data sourcesFour databases, three sources of grey literature and reference lists of systematic reviews were searched in March 2020.Eligibility criteriaEligible studies measured frailty in populations aged under 60 years using experimental or observational designs, published after 2000 in English.Data extraction and synthesisRecords were screened against review criteria. Study data were extracted with 20% of records checked for accuracy by a second researcher. Data were synthesised using a narrative approach.ResultsWe identified 268 studies that measured frailty in samples that included people aged under 60 years. Of these, 85 studies reported evidence about measure validity. No measures were identified that were designed and validated to identify frailtyexclusivelyin younger groups. However, in populations that included people aged overandunder 60 years, cumulative deficit frailty indices, phenotype measures, the FRAIL Scale, the Liver Frailty Index and the Short Physical Performance Battery all demonstrated predictive validity for mortality and/or hospital admission. Evidence of criterion validity was rare. The extent to which measures possess validity across the younger adult age (18–59 years) spectrum was unclear. There was no evidence about the impact of measuring frailty in younger populations on patient outcomes and care.ConclusionsLimited evidence suggests that frailty measures have predictive validity in younger populations. Further research is needed to clarify the validity of measures across the adult age spectrum, and explore the utility of measuring frailty in younger groups.