bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lycopene prevents cisplatin-induced liver tissue damage, without affecting concentrations of TNF-α or iNOS/NO inflammatory pathway
Authors: Rankovic Aleksandar , Nickovic Vanja , Novakovic Tanja , Mitic Nebojsa , Krdzic Biljana , Mitic Jadranka , Nikolic Gordana , Sokolovic Dusan 
Published: May 2021

IntroductionLiver inflammatory response occurring after toxic chemicals injection, such as cisplatin, causes the aggravation in liver damage. Lycopene, a carotenoid, has previously been proven to possess antioxidant, antiinflammatory and antiapoptotic properties. This study objective was to evaluate for the first time the protective effects of lycopene in cisplatin-induced liver damage based on the disturbances in serum and tissue inflammatory parameters. Also, to confirm the extent of changes in inflammation of the studied tissue, a microscopic analysis will be performed.Material and methodsWistar rats were divided into four experimental groups: (I) control; (II) lycopene (2 mg/kg); (III) cisplatin (10 mg/kg) and (IV) lycopene and cisplatin-treated (2 and 10 mg/kg, respectively) animals. After the experiment, we studied changes in serum liver tissue damage associated parameters (ALT, AST, and γ-GT) and liver inflammatory parameters (NO and TNF-α concentrations, myeloperoxidase and iNOS activity, as well as CD68 expression).ResultsApplication of lycopene prevented a rise in evaluated serum parameters induced by cisplatin, while at the same time it did not cause any harmful effect by itself. Lycopene, alone or in combination with cisplatin, decreased the values of all studied liver inflammatory parameters.ConclusionsWe can conclude that lycopene does not prevent liver tissue inflammatory decalin seen after cisplatin application, however, it prevents tissue damage arising from this cytostatic application.
Blood count-derived inflammatory markers predict time to Bacillus Calmette-Guérin failure in high-risk non-muscle-invasive bladder cancer
Authors: Ślusarczyk Aleksander , Piotr Zapała , Garbas Karolina , Zapała Łukasz , Borkowski Tomasz , Radziszewski Piotr 
Published: May 2021

IntroductionBacillus Calmette-Guérin (BCG) treatment failure remains a significant clinical problem in patients with high-risk non-muscle-invasive bladder cancer (NMIBC). The European Organization for Research and Treatment of Cancer (EORTC) and Spanish Urological Club for Oncological Treatment (CUETO) risk scores remain the most commonly used models in the prediction of NMIBC recurrence and progression. On the other hand, well-established predictors of BCG failure are still lacking. Our aim was to evaluate the utility of blood count-derived inflammatory markers for BCG failure prediction in patients with high-risk NMIBC.Material and methodsOne hundred and eighty-three consecutive patients with high-risk NMIBC, who underwent transurethral resection of the bladder tumour (TURBT) and were further treated with BCG instillations were included in the study. Bacillus Calmette-Guérin failure was retrospectively determined based on European Association of Urology 2019 guidelines. Differences in BCG failure-free survival were assessed using the log-rank test. Logistic regression was utilized for uni- and multivariate analysis.ResultsKaplan-Meier analysis revealed that patients with a high preoperative neutrophil-to-lymphocyte ratio (NLR > 2.3), platelet-to-lymphocyte ratio (PLR > 147), neutrophil-to-erythrocyte ratio (NER > 0.93), higher systemic inflammatory marker (SIM) score and with a low lymphocyte-to-monocyte ratio (LMR < 2.55) had shorter time to BCG failure (p < 0.05). In the multivariate model, all markers except for LMR remained a significant adjunct to the CUETO recurrence risk score when predicting BCG failure.ConclusionsOur study demonstrates the utility of blood count-derived inflammatory markers in the prediction of BCG failure in high-risk NMIBC. Implementation of NLR, PLR, NER and SIM score might be of clinical value especially when combined with the CUETO scoring system.
Coloniality and the Rise of Liberation Thinking during the Sixteenth Century
Authors: Ward Thomas 
Published: May 2021

This book delves into the inadequately explored, liberative side of Humanism during the late Renaissance. While some long-sixteenth-century thinking anticipates twentieth-century Liberation Theology, a broader description is simply "liberation thinking," which embraces its diverse, timeless, and sometimes nontheological aspects.
Two moments frame the treatment of American colonialism’s physical and mental pathways and the liberative response to them, known as liberation thinking. These are St. Thomas More’s Utopia, published in 1516, and Felipe Guaman Poma de Ayala’s thousand-page Nueva crónica y buen gobierno, completed one hundred years later. These works and others by Erasmus and Bartolomé de las Casas trace the development of the idea of human liberation in the face of degrading chattel and encomienda slavery as well as the peonage that gave rise to the hacienda system in the Americas. Catholic humanists such as More, Erasmus, Las Casas, and Guaman Poma developed arguments, theories, and even theology that attempted to deconstruct those subordinating structures.
Art and Politics
Authors: Segal Joes 
Published: May 2021

In Art and Politics, Segal explores the collision of politics and art in seven enticing essays. The book explores the position of art and artists under a number of different political regimes of the twentieth and twenty-first centuries, traveling around the world to consider how art and politics have interacted and influenced each other in different conditions.
Joes Segal takes you on a journey to the Third Reich, where Emil Nolde supported the regime while being called degenerate; shows us Diego Rivera creating Marxist murals in Mexico and the United States for anti-Marxist governments and clients; ties Jackson Pollock's drip paintings in their Cold War context to both the FBI and the CIA; and considers the countless images of Mao Zedong in China as unlikely witnesses of radical political change.
The Dutch Polder Model in science and research
Authors: Saarloos Wim , Dijck José 
Published: May 2021

Scientific research in the Netherlands is doing remarkably well. Dutch researchers, universities and institutes reside at or near the top of international rankings.
In this essay, José van Dijck and Wim van Saarloos, the president and vice-president of the Royal Netherlands Academy of Arts and Sciences (KNAW), explore how such a small country could become a global player in science and research. They highlight interconnectedness, collaboration, trust, and interwoven research and education among the quintessentially Dutch factors that paved the way to the success.
They also show, however, that the country's efforts to reach the top sometimes chip away at these trusted foundations. Investments in its research base are lagging, and some typically Dutch strengths have recently come under pressure.
They close off with some suggestions on how the country may turn the tide, prolong its great achievements, and ensure a leading role for Dutch research in the nation's future.
Managing Authentic Relationships
Authors: Wijers Jean Paul ,   Institute of Strategic Relationship Management
Published: May 2021

In an increasingly connected world, Strategic Relationship Management is a vital capability for successful organizations. The book Managing Authentic Relationships; Facing New Challenges in a Changing Context focuses on building and managing a strong network and reciprocal relationships for the entire organization by implementing a professional relationship management approach at strategic, tactical and operational level.
Professional relationship management makes valuable and measurable contributions to the strategic goals of an organization by: Expanding the organization's strategy to a Relationship Management Strategy; Efficiently managing relationships and correctly mapping stakeholders; Embedding clear responsibility for relationship management throughout the organization; Measuring results and calculating the Return-on-Relationship; Developing strong networking skills and networkers who are able to act as eyes and ears for the organization; Organizing effective networking activities with measurable results.
This book also offers a holistic view. Managing authentic relationships requires a shared understanding of what relationships are. It is impossible to develop successful relationship management without authentic relationships based on trust and reciprocity.
EU Pension Law
Authors: Meerten Hans 
Published: May 2021

EU pension law is a relatively new and rapidly growing field. The call for a broader practical understanding of EU pension law is growing, as pension markets are increasingly internationalized.
The handbook EU Pension Law discusses the most important financial EU legislation (IORP and PEPP) and non-financial legislation (such as the Charter of Fundamental Rights of the European Union) and its consequences for pensions. The book contains a collection of relevant articles and offers necessary basic knowledge. More importantly, it contains interesting practical cases, creating a unique bridge between theory and practice. Whether you are a student, a committed policymaker, an experienced market practitioner, or someone interested in European pension developments, EU Pension Law is designed for you.
Chapters on Interdisciplinary Research and Research Skills
Authors: Gaast Koen , Keestra Machiel , Koenders Laura , Menken Steph , Post Ger ,   Instituut voor Interdisciplinaire Studies
Published: May 2021

This book is a special edition, compiled for to the MSc Course Research Methodologies as taught at the Faculty of Aerospace Engineering at Delft University of Technology. It is a compilation of useful chapters from several sources on how to structure, set up, carry out and write up your (thesis) research to aid you in writing your research plan. Next to that it acts as a companion during your thesis research. After introducing you to the philosophy of scientific research, subsequent chapters each contribute to the different phases of your research. The book uniquely allows for the often multi- or interdisciplinary research many of you carry out, based on the established Dutch university tradition of (semi-)independent student research, creating a thread through the process for you to follow.
This edition is a collection of chapters from An Introduction to Interdisciplinary Research (2016), edited by Steph Menken and Machiel Keestra, and Academic Skills for Interdisciplinary Studies. Revised edition (2019), by Koen van der Gaast, Laura Koenders and Ger Post, published by Amsterdam University Press.
Prototipe Alat Simulasi Taman Pintar Dengan Pengontrol Bluetooth HC-05 Berbasis Mikrokontroller
Authors: Fahmi Muhammad , Santoso Budi , Maisyaroh Maisyaroh , Sunandar Agus , Wahyudi Ilham 
Published: May 2021

Abstrak: Pengontrol Taman Pintar dibuat untuk memudahkan aktivitas bertanam sehari-hari, aktivitas ini biasanya dilakukan secara manual yang tentu saja membuat orang kadang malas atau mempunyai kesibukan untuk melakukan aktivitas menyiram tanaman, menyalakan lampu, membuka gerbang taman. Bagi orang-orang yang memiliki rutinitas kesibukan yang padat akan sangat susah untuk mengurus taman sendiri dirumah, sehingga dengan membuat alat simulasi taman pintar menggunakan pengontrol Bluetooth HC-05 berbasis mikrokontroler dapat mempermudah para pemilik taman dirumah yang tidak memiliki banyak waktu luang untuk dapat menyiram taman, menyalakan lampu taman, membuka gerbang taman hanya dengan mengontrol melalui Bluetooth di smartphone android miliknya. Alat yang dibuat ini memakai komponen elektronik yaitu, Atmega16, Bluetooth HC-05, Motor Servo, dan Relay. Komponen-komponen elektronik tersebut digunakan untuk mendukung sistem otomatis yang akan dibuat. Alat ini memiliki kelebihan dapat mengontrol penyiraman tanaman, membuka gerbang atau pintu taman, menyalakan lampu taman hanya dengan mengontrol melalui smartphone android tanpa harus memerlukan tenaga yang banyak.

Kata kunci: atmega16, bluetooth hc-05, motor servo, relay.

Abstract: Smart Park controllers are made to facilitate daily farming activities, this activity is usually done manually which of course makes people sometimes lazy or have a busy life doing activities to water plants, turn on lights, open garden gates. For people who have a busy routine, it will be very difficult to manage their own garden at home, so making a smart garden simulation tool using a microcontroller-based Bluetooth HC-05 controller can make it easier for garden owners at home who don't have much free time to be able to water the garden. , turn on the garden light, open the garden gate by simply controlling via Bluetooth on his android smartphone. This tool is made using electronic components, namely, Atmega16, Bluetooth HC-05, Servo Motor, and Relay. These electronic components are used to support the automatic system to be created. This tool has the advantage of being able to control plant watering, open garden gates or doors turn on garden lights by simply controlling via an Android smartphone without requiring a lot of energy.

Keywords: atmega16, bluetooth hc-05, motor servo, relay.
Penerapan Konsep Model View Controller Pada Sistem Informasi Manajemen Data Terintegrasi
Authors: Ramadan Rino 
Published: May 2021

Abstrak: Manajemen data terintegrasi merupakan sebuah pendekatan untuk memfasilitasi manajemen data dan meningkatkan kinerja. Biasanya manajemen data terintegrasi terdiri dari lingkungan modular yang terintegrasi untuk mengelola data aplikasi perusahaan, dan mengoptimalkan aplikasi berbasis data selama masa pakainya. Saat ini manajemen data yang ada masih kurang konsisten dalam melakukan capaian target tingkat pengelolaan, beberapa operasi masih perlu di otomatiskan dan di sederhanakan, diperlukannya dukungan manajemen data untuk pertumbuhan, dibutuhkannya fasilitas penyelarasan serta konsistensi tata kelola data. Tujuan penelitian ini adalah membangun sebuah sistem informasi manajemen data terintegrasi berbasis website untuk membantu staff dalam mengelola data penerimaan mahasiswa baru ubsi secara terintegrasi. Pembangunan Sistem berbasis web ini menggunakan bahasa pemrograman PHP dan database MySQL, dengan menerapkan konsep Model View Controller (MVC) dalam teknik pemrogramannya. Penelitian ini menghasilkan sebuah aplikasi sistem informasi manajemen data terintegrasi berbasis web, yang mengintegrasikan data terhadap aplikasi lainnya agar siklus hidup aplikasi menjadi lebih praktis dan efisien. Penelitian ini memberikan arahan yang jelas tentang bagaimana sebaiknya membangun sebuah sistem informasi berbasis web dengan baik, sehingga tidak menyulitkan pemrogram web saat harus memperbaiki atau mengembangkan sistem di kemudian hari.

Kata kunci: Data terintegrasi, Konsep model view controller, Sistem manajemen.

Abstract: Integrated data management is an approach to facilitate data management and improve performance. Typically integrated data management consists of an integrated modular environment for managing enterprise application data, and optimizing data-driven applications over their lifetime. Currently, existing data management is still inconsistent in achieving management level targets, several operations still need to be automated and simplified, data management support is needed for growth, alignment facilities and consistency of data governance are needed. The purpose of this research is to build an integrated data management information system based on a website to assist staff in managing the data of new student admissions in an integrated way. This web-based system development uses the PHP programming language and MySQL database, by applying the Model View Controller (MVC) concept in its programming techniques. This research produces a web-based integrated data management information system application, which integrates data with other applications so that the application life cycle becomes more practical and efficient. This study provides clear directions on how best to build a web-based information system properly, so that it doesn't make it difficult for web programmers to repair or develop the system at a later date.

Keywords: Integrated data, Management system, Model View Controller Concept.
Sistem Monitoring Kedalaman Dan Kekeruhan Air Berbasis Internet Of Things
Authors: Herlambang Nurdian , Pramudita Rully , Retnoningsih Endang 
Published: May 2021

Abstrak: Berdasarkan hasil penelitian yang dilakukan terdapat masalah yang ditemukan yaitu pada saat proses penggecekan kedalaman dan kekeruhan kualitas air masih menggunakan sistem secara manual yang melibatkan peran karyawan dalam melakukan proses penggecekannya dengan menggunakan alat turbidity meter dan level transmitter. Oleh sebab itu peneliti memberikan masukkan dan saran untuk proses penggecekan kedalaman dan kekeruhan air tersebut menggunakan sensor dalam mendapatkan hasil penggecekannya dan sistem berbasis internet of things untuk memonitoring hasil dari sensor yang digunakan. Lalu hasil dari prosesnya dapat dimonitoring langsung kedalam platform website. Didalam penelitian ini penulis menggunakan metode logika fuzzy logic untuk memprogram perangkat kerasnya dan hasil monitoringnya menggunakan website dengan framework codeigneter. Yang bertujuan untuk membangun sistem monitoring penggecekan kedalaman dan kekeruhan kualitas air secara otomatis menggunakan sensor ultrasonic dan sensor turbidity.

Kata kunci: fuzzy logic, internet of things, sensor turbidity, sensor ultrasonic, sistem monitoring

Abstract: Based on the results of the research conducted, there were problems found that when the process of checking the depth and turbidity of water quality was still using a manual system that involved the role of employees in carrying out the checking process using a turbidity meter and level transmitter. Therefore, researchers provide input and suggestions for the process of checking the depth and turbidity of the water using sensors to get the results of checking and an internet of things based system to monitor the results of the sensors used. Then the results of the process can be monitored directly into the website platform. In this research, the writer uses fuzzy logic logic method to program the hardware and the monitoring results use a website with codeigneter framework. Which aims to build a monitoring system for checking the depth and turbidity of water quality automatically using ultrasonic sensors and turbidity sensors..

Keywords: fuzzy logic, internet of things, monitoring systems, turbidity sensors, ultrasonic sensors
Aplikasi Media Pembelajaran Pengenalan Kosakata Harian Bahasa Arab Dengan Metode Multimedia Development Life Cycle (MDLC)
Authors: Alfian Ari Nurul 
Published: May 2021

Abstrak: Salah satu solusi untuk mengatasi permasalahan dalam pembelajaran adalah dengan pemanfaatan media pembelajaran. Media pembelajaran merupakan sebuah alat bantu komunikasi antara guru dan siswa untuk mempermudah penyampaian suatu informasi dalam sebuah pembelajaran. Penelitian yang telah dilakukan pada pengembangan media pembelajaran Adobe Flash CS6 mengenai kosakata harian Bahasa Arab. Tujuan dari penelitian ini adalah untuk merancang dan mengembangkan media pembelajaran dan uji penerimaan (user acceptance test). Aplikasi yang dikembangkan memiliki fitur yang berguna untuk meningkatkan kemampuan siswa mempelajari dan menghapal kosakata serta pengucapan yang benar. Program aplikasi telah diuji pada jenis perangkat komputer yang berbeda serta diuji kepada guru dan siswa secara sampling. Hasil penelitian menunjukkan bahwa aplikasi media pembelajaran kosakata Bahasa Arab dapat bekerja dengan baik dan responden, secara umum, menyatakan bahwa program aplikasi memuaskan untuk digunakan dalam mempelajari kosakata Harian Bahasa Arab untuk siswa.

Kata kunci: adobe flash CS6, kosakata bahasa arab, mufrodat, media pembelajaran, multimedia, user acceptance test.

Abstract: One solution to solving problems in learning is the use of learning media. Learning media is a communication tool between teachers and students to facilitate the delivery of information in a lesson. Research that has been done on the development of Adobe Flash CS6 learning media regarding daily Arabic vocabulary. The purpose of this study is to design and develop instructional media and a user acceptance test. The application developed has useful features to improve students' ability to learn and memorize vocabulary and correct pronunciation. The application program has been tested on different types of computer equipment and tested on teachers and students by sampling. The results showed that the application of Arabic vocabulary learning media could work well and respondents, in general, stated that the application program was satisfactory to be used in learning Arabic daily vocabulary for students.

Keywords: adobe flash CS6, mufrodat, learning media, multimedia, user acceptance test, vocabulary arabic
Pelatihan Penggunaan Mesin Pembuatan Pellet Pakan Ikan Dalam Upaya Peningkatan Produktifitas Kelompok Pembudidayaan Ikan
Authors: Nugroho Arif Setyo 
Published: May 2021

Penduduk kreatif Kelurahan Ngadirejo Kabupaten Sukoharjo melakukan budidaya dan pengembangan ikan lele, hasilnya sudah bisa dirasakan manfaatnya, tetapi mengalami kendala dalam pengembangan usaha pembudidayaan dan pengembangan ikan lele. Kendala atau permasalahn yang dihadapi adalah ketika harga pakan naik tetapi harga ikan hasil panen turun, sehingga FCR nya sangat kecil sehingga peternak rugi. Solusi yang ditawarkan sesuai hasil diskusi dengan PokDaKan adalah berusaha membuat pakan plus sehingga tidak tergantung dari pakan pabrik. Pakan lele berbentuk pelet dengan tambahan prebiotik untuk tambahan suplemen pakan lele dengan sentuhan teknologi dengan sistem mesin pengolah prebiotik sistem mix hot rotary dan mesin pembuat pellet apung. Teknologi tersebut sangat tepat untuk PokDaKan karena mampu menanggulangi permasalahan yang dihadapi. Mesin pellet bisa menghasilkan 80 kg /jam pelet. Dengan membuat sendiri pellet pakan ikan sesuai dengan yang dipraktekan, dengan modal uang Rp 500 ribu untuk belanja bahan pembuatan pellet bisa dibuat pelet kurang lebih 140 kg pellet. Lebih hemat dan pakan buatan sendiri lebih bergizi.