bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ion dynamics at the energy-deprived tripartite synapse
Authors: Kalia Manu , Meijer Hil G.E. , van Gils Stephan A. , van Putten Michel J.A.M. , Rose Christine R. 
Published: March 2021

AbstractThe anatomical and functional organization of neurons and astrocytes at ‘tripartite synapses’ is essential for reliable neurotransmission, which critically depends on ATP. In low energy conditions, synaptic transmission fails, accompanied by a breakdown of ion gradients, changes in membrane potentials and cell swelling. The resulting cellular damage and cell death are causal to the often devastating consequences of an ischemic stroke. The severity of ischemic damage depends on the age and the brain region in which a stroke occurs, but the reasons for this differential vulnerability are far from understood. In the present study, we address this question by developing a comprehensive biophysical model of a glutamatergic synapse to identify key determinants of synaptic failure during energy deprivation. Our model is based on fundamental biophysical principles, includes dynamics of the most relevant ions, i.e., Na+, K+, Ca2+, Cl−and glutamate, and is calibrated with experimental data. It confirms the critical role of the Na+/K+-ATPase in maintaining ion gradients, membrane potentials and cell volumes. Our simulations demonstrate that the system exhibits two stable states, one physiological and one pathological. During energy deprivation, the physiological state may disappear, forcing a transit to the pathological state, which can be reverted when blocking voltage-gated Na+and K+channels. Our model predicts that the transition to the pathological state is favoured if the extracellular space fraction is small. A reduction in the extracellular space volume fraction, as, e.g. observed with ageing, will thus promote the brain’s susceptibility to ischemic damage. Our work provides new insights into the brain’s ability to recover from energy deprivation, with translational relevance for diagnosis and treatment of ischemic strokes.Author summaryThe brain consumes energy to keep ion concentrations at normal working conditions. In the case of energy deprivation (ED), e.g., during a stroke, synaptic communication fails first. Inspired by our recent experimental work on ED, we formulated a novel computational model to explore initial events during ED. Our model reproduces time courses for several ions from different experimental data. In some cases, the system returns to baseline upon restoring energy supply. In others, we observe that neurons and astrocytes cannot recover accompanied by cell swelling. There is a threshold depending on the depth and duration of ATP depletion differentiating these cases. Also, smaller extracellular spaces hamper recovery more. This result may explain clinical observations of increased vulnerability to stroke as the size of the extracellular space shrinks with ageing.
Temperature-gradient analyzers for non-resonant inelastic X-ray scattering
Authors: Ishikawa Daisuke , Baron Alfred Q. R. 
Published: March 2021

The detailed fabrication and performance of the temperature-gradient analyzers that were simulated by Ishikawa & Baron [(2010).J. Synchrotron Rad.17, 12–24] are described and extended to include both quadratic and 2D gradients. The application of a temperature gradient compensates for geometric contributions to the energy resolution while allowing collection of a large solid angle, ∼50 mrad × 50 mrad, of scattered radiation. In particular, when operating relatively close to backscattering, π/2 − θB= 1.58 mrad, the application of a gradient of 1.32 K per 80 mm improves the measured total resolution from 60 to 25 meV at the full width at half-maximum, while when operating further from backscattering, π/2 − θB= 6.56 mrad, improvement from 330 to 32 meV is observed using a combination of a gradient of 6.2 K per 80 mm and dispersion compensation with a position-sensitive detector. In both cases, the operating energy was 15.8 keV and the incident bandwidth was 22 meV. Notably, the use of a temperature gradient allows a relatively large clearance at the sample, permitting installation of more complicated sample environments.
High-order derivative fusion estimation of rotorcraft angular rate
Authors: Liu Changwu , Wang Haowen , Jiang Chen 
Published: March 2021

Purpose
The paper aims at developing a novel algorithm to estimate high-order derivatives of rotorcraft angular rates to break the contradiction between bandwidth and filtering performance because high-order derivatives of angular rates are crucial to rotorcraft control. Traditional causal estimation algorithms such as digital differential filtering or various tracking differentiators cannot balance phase-lead angle loss and high-frequency attenuation performance of the estimated differentials under the circumstance of strong vibration from the rotor system and the rather low update rate of angular rates.

Design/methodology/approach
The algorithm, capable of estimating angular rate derivatives to maximal second order, fuses multiple attitude signal sources through a first-proposed randomized angular motion maneuvering model independent of platform dynamics with observations generated by cascaded tracking differentiators.

Findings
The maneuvering flight test on 5-kg-level helicopter and the ferry flight test on 230-kg-level helicopter prove such algorithm is feasible to generate higher signal to noise ratio derivative estimation of angular rates than traditional differentiators in regular flight states with enough bandwidth for flight control.

Research limitations/implications
The decrease of update rate of input attitude signals will weaken the bandwidth performance of the algorithm and higher sampling rate setting is recommended.

Practical implications
Rotorcraft flight control researchers and engineers would benefit from the estimation method when implementing flight control laws requiring angular rate derivatives.

Originality/value
A purely kinematic randomized angular motion model for flight vehicle is first established, combining rigid-body Euler kinematics. Such fusion algorithm with observations generated by cascaded tracking differentiators to estimate angular rate derivatives is first proposed, realized and flight tested.
Consumer brand engagement in the US–China trade war
Authors: Lee Yi Hsuan , Wei Chiou-Fong , Lee Bruce C. Y. , Cheng Ya-Yun , Chen Yao 
Published: March 2021

PurposeThis study examines whether consumer brand engagement (CBE) can mitigate the negative effects of economic animosity (EA) on purchase intention (PI) and strengthen the positive effect of country-of-origin (COO) on PI.Design/methodology/approachUsing questionnaires distributed to 372 young Chinese adults, the study collected PI data for US products in the Chinese market. Partial least square structural equation modeling was adopted.FindingsThis study found a positive relationship between COO and CBE and a negative relationship between EA and CBE. CBE exhibits a partial mediating effect in the relationship between COO and PI and a full suppression effect on EA toward PI.Research limitations/implicationsThis research is limited to China; future research could extend this framework to the United States.Practical implicationsThis study contributes to relationship marketing knowledge. Furthermore, it provides new tools for multinational corporations to deploy their marketing strategies and avoid negative consequences stemming from the EA effect in the Chinese market following the US–China trade war.Originality/valueThis study is the first to extend COO and EA research to CBE discipline.
A COVID-19 contextual study of customers’ mistreatment and counterproductive work behavior at coffee cafés
Authors: Ahmed Ishfaq , Islam Talat , Ahmad Saima , Kaleem Ahmad 
Published: March 2021

PurposeThe issue of customer mistreatment in food and retail sectors has come under the spotlight during the COVID-19 crisis. The purpose of this paper is to examine the problem in the COVID-19 pandemic context and study its implications for employee counterproductive behavior in the workplace. Specifically, this study aims to investigate the relationship between customer mistreatment and employee counterproductive behavior by considering the mediating role of cognitive rumination and moderating role of servant leadership at coffee cafés that operated during the COVID-19 smart lockdown period.Design/methodology/approachStructured questionnaires were distributed to 479 frontline staff working at cafés and coffee shops located in two large cities of Pakistan. The questionnaire data were analyzed by using bootstrapped regression procedures to determine how the investigated variables influenced counterproductive work behavior during the pandemic.FindingsThe findings revealed a positive influence of customer mistreatment on counterproductive work behavior both directly as well as indirectly in the presence of employee rumination as a mediator. Furthermore, the presence of servant leadership at cafés and coffee shops was found to moderate the impact of customer mistreatment during the pandemic.Originality/valueThe study offers a novel insight into the relationships between mistreatment by customers, counterproductive work behavior, employee rumination and servant leadership in the COVID-19 pandemic context, hitherto unexplored.
Spain's reputation in China: analysing its effects on attitudes towards Spanish olive oil
Authors: García Juan A. , Ruiz Belén 
Published: March 2021

PurposeThe objective of this paper is to analyse the elements that influence Spain's reputation among Chinese consumers, and to evaluate to what extent this country's reputation has an impact on their perceived quality of Spanish olive oil (SOO) and their intentions to purchase and recommend SOO.Design/methodology/approachThis study was carried out by surveying 399 potential olive oil consumers in China (256 of whom were familiar with olive oil and 143 of whom had no previous familiarity with the product, although they stated their intentions to consume it). The proposed hypotheses were tested using covariance-based structural equation modelling (CB-SEM).FindingsThe results show that: (1) Spain's reputation among Chinese consumers can be principally explained by its appealing environment and advanced economy; (2) reputation does not have a direct impact on intentions to purchase and recommend SOO (summary construct effect), but rather has an indirect impact thanks to the perceived quality of SOO (halo effect), and (3) familiarity with olive oil moderates these relationships.Originality/valueNo previous study has analysed this question for this food product category (olive oil), country of origin (Spain) and target market (China). This study, therefore, provides new empirical evidence regarding the formation process of Spain's reputation among Chinese olive oil consumers and the effect of the country of origin on the Chinese olive oil market. These results provide countries' policymakers with criteria for competitive country reputation management.
Wine consumption preferences among generations X and Y: an analysis of variability
Authors: Rodríguez-Donate Mª Carolina , Romero-Rodríguez Margarita E. , Cano-Fernández Víctor Javier 
Published: March 2021

PurposeThis paper compares the socio-demographic features, wine consumption preferences and habits of individuals of Generations X and Y. The influence of age, as a life cycle effect, on individuals' consumption preferences from the same generation is analysed. In addition, the generational effect and period effect on consumption by each generation are studied to ascertain changes in preferences due to specific values of their birth cohort or period.Design/methodology/approachMixed ordered logit models are estimated to identify which traits influence the probability of consuming a certain quantity of wine for each generation. The variability of the effects of different variables on the consumption decision is analysed in depth, as a reflection of the unobserved heterogeneity present in individuals' decisions. For this purpose, data from two exhaustive surveys carried out in Tenerife (Canary Islands) over a time interval of 13 years are used.FindingsIndividuals' age and period are relevant factors in the consumption decision. There are some similarities in the behaviour of both generations, although the variability of the effects of some individual traits is greater for Generation X.Originality/valueThis paper contributes to a better understanding of the profile of wine consumers from different generations through a joint analysis of age effects, period and cohort, which have rarely been addressed jointly in the literature. In addition, it provides an exhaustive analysis of the heterogeneity in consumption preferences that highlights the variability of the effects found.
Job stress and employee outcomes: employment practices in a charity
Authors: Wang Wen , Seifert Roger 
Published: March 2021

PurposeThe study intends to examine employee relations with a changing workforce resulting from the business-like transformation in the charity sector. The authors investigated sector-specific employment practices that can alleviate job stress (as a given and which has been made worse by the transformation). Developed from the intrinsic and extrinsic motivation framework, the findings can inform human resource management practices in its new efficiency-seeking business model.Design/methodology/approachThe authors collected both quantitative (through a staff survey and administrative records of sick leave in the previous 12 months) and qualitative data (through interviews and focus groups) from one branch of an internationally well-established and UK-based religious charity between 2017 and 2018.FindingsThe quantitative results support a strong mediating effect of job satisfaction between job stress and staff sick leave. The negative correlation shown between job stress and job satisfaction is subject to paid staff perception of meaningful work and their level of involvement in decision-making, with the latter having a stronger moderating effect. The qualitative data provides further contextualized evidence on the findings.Practical implicationsIt is important for charities to uphold and reflect their charitable mission towards beneficiaries and paid staff during the shift to an efficiency-seeking business model. Charities should involve their new professional workforce in strategic decision-making to better shape a context-based operational model.Originality/valueThe study examined employee relations in the non-profit charity sector with a changing workforce during the transition to a more business-oriented model. In particular, the authors revealed sector-specific factors that can moderate the association between job stress and absenteeism, and thereby contribute to the understanding of human resource management practices in the sector.
Exploring the development of entrepreneurial identity in a learning-by-doing entrepreneurial project environment
Authors: Chen Shin-Horng , Wang Wei-Tsong , Lu Chih-Tsen 
Published: March 2021

PurposeUnderstanding the construction of individual entrepreneurial identity for entrepreneurship education is an important but understudied issue. Prior studies indicate that entrepreneurship learning is associated with not only learning critical entrepreneurial skills and knowledge but also facilitating the construction of a personal entrepreneurial identity. However, educators are constantly challenged by the task of facilitating such an identity within students via learning-by-doing processes in the context of entrepreneurial teams. Additionally, while effective conflict management is essential to productive entrepreneurial learning in entrepreneurial teams, studies that investigate the relationships between interpersonal conflicts of entrepreneurial teams and the students' entrepreneurial identity are absent.Design/methodology/approachThe approach of an in-depth case study was adopted to achieve our research purpose.FindingsA conceptual model that describes the construction of the entrepreneurial identity of students of entrepreneurial teams in a learning-by-doing environment from the perspectives of conflicts and task characteristics are developed.Research limitations/implicationsThe research findings highlight the preliminary relationships between task characteristics (i.e. task interdependence, task uncertainty, resource competition and tension regarding responsibility allocation) and interpersonal conflicts of entrepreneurial teams, and their impacts on the entrepreneurial identity of team members.Originality/valueThis study is among the first group of studies that especially explores the relationships among task characteristics of entrepreneurship projects, interpersonal conflicts and the development of students' entrepreneurial identity.
Housing price volatility: uncertainty, an asymmetric econometric analysis – some European country experiences
Authors: Ghosh Sudeshna 
Published: March 2021

Purpose
The purpose of this paper is to examine the asymmetric impact of economic policy uncertainty (EPU) on the volatility of the housing price index (RP) based on quarterly observations from major European countries, namely, France, Germany, Sweden, Greece Italy and the UK.

Design/methodology/approach
The nonlinear autoregressive distributed lag model method is used to investigate the asymmetric impact of EPU on RP. In addition to considering EPU as the explanatory variable, industrial production (IP) (as a proxy for economic growth), interest rate (I), inflationary tendency (Consumer Price Index) and share prices (S) are included as major control variables. The period of the observations runs from 1996Q1 to 2019Q1.

Findings
The Wald test confirms the long-run asymmetric relationship for all countries. The alternative specification of the data sets reconfirms the asymmetric impact on RP in the long run, thereby verifying the robustness of the study.

Research limitations/implications
The study has implications for investors seeking to incorporate housing price behaviour within their portfolio structure. The analysis and findings are constrained by the availability of data.

Originality/value
This is one of the few studies on housing price dynamics related to the major economies of the European region that explore asymmetries. Additionally, it is the first to explore the asymmetry dynamics using the EPU variable.
Intelligent and efficient? An empirical analysis of human–AI collaboration for truck drivers in retail logistics
Authors: Loske Dominic , Klumpp Matthias 
Published: March 2021

PurposeTechnological advances regarding artificial intelligence (AI) are affecting the transport sector. Although fully autonomous delivery, or self-driving trucks, are not operating currently, various AI applications have become fixed components of cargo vehicles. Since many research approaches primarily concentrate on the technical aspects of assistance systems (ASs), the economic question of how to improve efficiency is seldom addressed. Therefore, the purpose of this paper is to apply an efficiency analysis to measure the performance of truck drivers supplying retail stores.Design/methodology/approachFor this comparative study, 90 professional truck drivers in three groups are compared with (1) trucks without AS, (2) trucks with AS that cannot be turned off and (3) trucks with AS that can be turned off. First, we build a model investigating the impact of performance expectation, effort expectation, social influence and facilitating conditions on the behavioural intention to use AS. Second, we explore the impact of truck drivers' behavioural intention on actual technology use, misuse and disuse; operationalize these constructs; and merge them with our behavioural constructs to create one econometric model.FindingsThe human–AI system was found to be the most efficient. Additionally, behavioural intention to use ASs did not lead to actual usage in the AI-alone observation group, but did in the human–AI group. Several in-depth analyses showed that the AI-alone group used AS at a higher level than the human–AI group, but manipulations through, for example, kickdowns or manual break operations led to conscious overriding of the cruise control system and, consequently, to higher diesel consumption, higher variable costs and lower efficiency of transport logistical operations.Research limitations/implicationsEfficiency analysis with data envelopment analysis is, by design, limited by the applied input and output factors.Originality/valueThis study represents one of the first quantitative efficiency analyses of the impact of digitalization on transport performance (i.e. truck driver efficiency). Furthermore, we build an econometric model combining behavioural aspects with actual technology usage in a real application scenario.
The relationships between CEOs' psychological attributes, top management team behavioral integration and firm performance
Authors: Aljuhmani Hasan Yousef , Emeagwali Okechukwu Lawrence , Ababneh Bashar 
Published: March 2021

PurposeThis study aims to investigate the impact of chief executive officers' (CEO’s) core self-evaluation and grandiose narcissism on firm performance. This work combines bright and dark personality sides to explore how complex CEO's behavioral characteristics affect firms' outcomes. In addition, top management team (TMT) behavioral integration is considered as an organizational setting that acts as a conductive device bridging CEOs behavioral characteristics with firms' performance.Design/methodology/approachThe data for this study are based on 187 respondents, including CEOs and TMTs, across medium and large firms in Turkey through an online survey using a questionnaire. Structural equation modeling (SEM) was used to analyze the data collected.FindingsThe study finds that only CEO-TMT narcissism and TMT behavioral integration have a positive direct effect on firm financial performance. Contrary to expectations, CEO-TMT core self-evaluation has a negative direct effect on firm performance. Moreover, the results show that environmental dynamism interacts positively and significantly with CEO-TMT narcissism. Thus, the claim that TMT behavioral integration has a mediating effect is not supported in the context of medium and large firms in Turkey.Originality/valueThis study contributes to the upper echelons theory (UET) literature by highlighting the boundary conditions under which narcissistic CEOs can interact with more behaviorally integrated TMT members to exchange information, make joint decisions and collaborate in a relatively dynamic environment, as well as aggregating the bright side and dark side of CEOs personality traits and examining their effects alongside those of TMT behavioral integration on the firm performance. Finally, this study enriches the upper echelons literature by providing evidence from Turkey.