bluuebunny/crossref_metadata_2025_split huggingface dataset:
Elastic Metasurfaces for Full Wavefront Control and Low-Frequency Energy Harvesting
Authors: Lin Zhenkun , Tol Serife 
Published: February 2021

Abstract
Controlling and manipulating elastic/acoustic waves via artificially structured metamaterials, phononic crystals, and metasurfaces have gained an increasing research interest in the last decades. Unlike others, a metasurface is a single layer in the host medium with an array of subwavelength-scaled patterns introducing an abrupt phase shift in the wave propagation path. In this study, an elastic metasurface composed of an array of slender beam resonators is proposed to control the elastic wavefront of low-frequency flexural waves. The phase gradient based on Snell’s law is achieved by tailoring the thickness of thin beam resonators connecting two elastic host media. Through analytical and numerical models, the phase-modulated metasurfaces are designed and verified to accomplish three dynamic wave functions, namely, deflection, non-paraxial propagation, and focusing. An oblique incident wave is also demonstrated to show the versatility of the proposed design for focusing of wave energy incident from multiple directions. Experimentally measured focusing metasurface has nearly three times wave amplification at the designed focal point which validates the design and theoretical models. Furthermore, the focusing metasurface is exploited for low-frequency energy harvesting and the piezoelectric harvester is improved by almost nine times in terms of the harvested power output as compared to the baseline harvester on the pure plate without metasurface.
Experimental and Numerical Analysis of Shear Process of a High Particle Content Bonding Material
Authors: Yang Yizhan , Li Jiliang , Chen Jiankang 
Published: February 2021

Abstract
In this study, polymer-bonded sugar (PBS) is used as a substitute material for polymer-bonded explosive (PBX), and the shear failure process of PBS under compressive loading. First, the shear failure process of PBS was analyzed by a series of experiments, and it was found that the shear band appearing on the surface of the specimen was not symmetrical. Further theory analysis showed that it was triggered by the evolution of asymmetric damage caused by internal defects in the material. In addition, through investigating the distribution of experimental scatters, we found that the material undergoes a relatively long period of internal microstructure adjustment before shear failure occurs, this adjustment will undoubtedly affect the evolution of the shear band. More importantly, a data density method was used to quantify the adjustment process. Finally, by using finite element simulation, the effects of matrix–particle interface strength on the mechanical response or damage evolution of the PBS were thoroughly examined. This research has reference significance for understanding the damage evolution process of high particle content composite materials.
The Role of Geometrical Parameters in the Lubrication of the Swiss Lever Escapement
Authors: Roda-Buch Alejandro , Magnin Valentine A. M. , Maldonado Sandra Guadalupe , Mischler Stefano 
Published: February 2021

Abstract
The lubrication regimes of a contact pair escapement-ruby pallet of a Swiss lever escapement have been investigated combining the theory of fluid lubrication with a well-established kinematic and inverse dynamic multibody model. The kinematic analytical results have been confronted with experimental measurements. The developed model allows to easily obtain, for the three operating phases of the Swiss lever escapement, the relative speed and the contact forces and, by considering a hydrodynamic lubrication regime, the lubricant minimum film thickness and the coefficient of friction. The presented formulation allows to study the influence of crucial technical parameters in the Swiss lever escapement lubrication. The spout radii of curvature have been identified as the optimal parameters to control the lubrication regimes in the pallet/escapement contacts. In that sense, an interesting result is that the lubrication regime moves away from the boundary lubrication by increasing these radii.
A Bayesian Approach for Inferring Sea Ice Loads
Authors: Parno Matthew , Hodgdon Taylor , West Brendan , O’Connor Devin , Song Arnold 
Published: February 2021

AbstractThe Earth’s climate is rapidly changing and some of the most drastic changes can be seen in the Arctic, where sea ice extent has diminished considerably in recent years. As the Arctic climate continues to change, gathering in situ sea ice measurements is increasingly important for understanding the complex evolution of the Arctic ice pack. To date, observations of ice stresses in the Arctic have been spatially and temporally sparse. We propose a measurement framework that would instrument existing sea ice buoys with strain gauges. This measurement framework uses a Bayesian inference approach to infer ice loads acting on the buoy from a set of strain gauge measurements. To test our framework, strain measurements were collected from an experiment where a buoy was frozen into ice that was subsequently compressed to simulate convergent sea ice conditions. A linear elastic finite element model was used to describe the response of the deformable buoy to mechanical loading, allowing us to link the observed strain on the buoy interior to the applied load on the buoy exterior. The approach presented in this paper presents an instrumentation framework that could use existing buoy platforms as in situ sensors of internal stresses in the ice pack.
Memory-Efficient Modeling and Slicing of Large-Scale Adaptive Lattice Structures
Authors: Liu Shengjun , Liu Tao , Zou Qiang , Wang Weiming , Doubrovski Eugeni L. , Wang Charlie C. L. 
Published: February 2021

Abstract
Lattice structures have been widely used in various applications of additive manufacturing due to its superior physical properties. If modeled by triangular meshes, a lattice structure with huge number of struts would consume massive memory. This hinders the use of lattice structures in large-scale applications (e.g., to design the interior structure of a solid with spatially graded material properties). To solve this issue, we propose a memory-efficient method for the modeling and slicing of adaptive lattice structures. A lattice structure is represented by a weighted graph where the edge weights store the struts’ radii. When slicing the structure, its solid model is locally evaluated through convolution surfaces in a streaming manner. As such, only limited memory is needed to generate the toolpaths of fabrication. Also, the use of convolution surfaces leads to natural blending at intersections of struts, which can avoid the stress concentration at these regions. We also present a computational framework for optimizing supporting structures and adapting lattice structures with prescribed density distributions. The presented methods have been validated by a series of case studies with large number (up to 100 M) of struts to demonstrate its applicability to large-scale lattice structures.
A General Method for Constructing Planar Cognate Mechanisms
Authors: Sherman Samantha N. , Hauenstein Jonathan D. , Wampler Charles W. 
Published: February 2021

Abstract
Cognate linkages are mechanisms that share the same motion, a property that can be useful in mechanical design. This article treats planar curve cognates, that is, planar mechanisms with rotational joints whose coupler points draw the same curve, as well as coupler cognates and timed curve cognates. The purpose of this article is to develop a straightforward method based solely on kinematic equations to construct cognates. The approach computes cognates that arise from permuting link rotations and is shown to reproduce all of the known results for cognates of four-bar and six-bar linkages. This approach is then used to construct a cognate of an eight-bar and a ten-bar linkage.
Horsing Around: Escherichia coli ST1250 of Equine Origin Harboring Epidemic IncHI1/ST9 Plasmid with
bla
CTX-M-1
and an Operon for Short-Chain Fructooligosaccharide Metabolism
Authors: Valcek Adam , Sismova Petra , Nesporova Kristina , Overballe-Petersen Søren , Bitar Ibrahim , Jamborova Ivana , Kant Arie , Hrabak Jaroslav , Wagenaar Jaap A. , Madec Jean-Yves , Damborg Peter , van Duijkeren Engeline , Ewers Christa , Hordijk Joost , Hasman Henrik , Brouwer Michael S. M. , Dolejska Monika 
Published: February 2021

The relatedness of the equine-associated
Escherichia coli
strain ST1250 and its single- and double-locus variants (ST1250-SLV/DLV), obtained from horses in Europe, was studied by comparative genome analysis. A total of 54 isolates of
E. coli
ST1250 and ST1250-SLV/DLV from healthy and hospitalized horses across Europe (Czech Republic [
n
= 23], The Netherlands [
n
= 18], Germany [
n
= 9], Denmark [
n
= 3], and France [
n
= 1]) from 2008 to 2017 were subjected to whole-genome sequencing.
Long-term outcomes following primary versus secondary Boston keratoprosthesis type 1 implantation
Authors: Nayman Taylor , Bostan Cristina , Szigiato Andrei-Alexandru , Harissi-Dagher Mona 
Published: February 2021

Background/aimsTo compare long-term outcomes of primary versus secondary (postgraft failure) Boston keratoprosthesis type 1 (KPro) implantation.MethodsMedical records of patients at the Centre hospitalier de l’Université de Montréal having undergone KPro implantation between 2008 and 2017 were reviewed and included if they had a preoperative Snellen best-corrected visual acuity (BCVA) of 20/100 or worse and a minimum of 5 years of follow-up. Eighty-two eyes were separated into two cohorts (40 primary, 42 secondary KPro) and BCVA, complications and device retention were evaluated between groups.ResultsBCVA improved from baseline in both groups at each year; this was significant at all five postoperative years in the primary group and the first 3 years in the secondary group (p<0.05). Mean BCVA was similar between groups at 5 years (logarithm of minimal angle resolution 1.3±0.8 in the primary group vs 1.5±0.8 p<0.05). Idiopathic vitritis, choroidal detachment and new glaucoma occurred more after primary KPro (n=7, 17.5% vs n=1, 2.4%; n=11, 27.5% vs n=3, 7.14% and n=14, 35% vs n=6, 14%, respectively; p<0.05). Primary KPro had lower retention (n=28, 70% vs n=38, 91%, p<0.05) at final follow-up. There was more aniridia in the primary group (n=19, 48% vs n=6, 14%, p<0.01). Within each group, 50% of removals occurred in aniridic eyes.ConclusionPrimary KPro yielded favourable long-term visual outcomes but had more complications and lower retention rates than secondary KPro, likely explained by preoperative indications. Primary device implantation represents a favourable option for patients for whom grafts are likely to fail.
Association between body mass index and diabetic retinopathy in Asians: the Asian Eye Epidemiology Consortium (AEEC) study
Authors: Sabanayagam Charumathi , Sultana Rehena , Banu Riswana , Rim Tyler , Tham Yih Chung , Mohan Sunita , Chee Miao Li , Wang Ya Xing , Nangia Vinay , Fujiwara Kohta , Tai E Shyong , Song Su Jeong , Bikbov Mukharram M , Raman Rajiv , Cheng Ching Yu , Wong Tien Yin , Jonas Jost B 
Published: February 2021

Background/aimsObesity is a well-known risk factor for diabetes, but its association with diabetic retinopathy (DR) is inconclusive, in particular in Asians. We aimed to assess whether body mass index (BMI) is associated with the presence and severity of DR in Asian populations with diabetes.MethodsPooled analysis of individual-level cross-sectional data from 10 010 adults with diabetes who participated in 12 population-based studies conducted in China, India, Japan, Russia (Asian), Singapore and South Korea that were part of the Asian Eye Epidemiology Consortium (AEEC). BMI was calculated as weight in kilograms divided by height in square metres and categorised into normal (<25 kg/m2, reference), overweight (25–29.9 kg/m2) and obese (≥30 kg/m2). Any-DR (n=1669) and vision-threatening DR (VTDR, n=489) were assessed from digital retinal photographs and graded according to standard protocols. Each study was analysed separately using multivariable logistic regression models adjusted for age, sex, haemoglobin A1c%, systolic blood pressure and diabetes duration, and the estimated odds ratios (ORs) and 95% confidence interval (CIs) from all studies were then combined using random-effects models.ResultsIn multivariable models, obesity showed a significant inverse association with any-DR (pooled OR (95% CI) =0.74 (0.59 to 0.91)) and VTDR (0.75 (0.60 to 0.93)). Similarly, in continuous analysis, BMI showed a significant inverse association with both any-DR (0.93 (0.87 to 0.99)) and VTDR (0.79 (0.68 to 0.92) per SD increase). Overweight did not show a significant association with any-DR.ConclusionsAmong Asian adults with diabetes, both BMI and obesity showed an inverse association with DR. These findings warrant confirmation in further longitudinal studies.
Mental health among elite athletes in Norway during a selected period of the COVID-19 pandemic
Authors: Pensgaard Anne Marte , Oevreboe Tom Henning , Ivarsson Andreas 
Published: February 2021

ObjectiveTo investigate the prevalence of mental health problems and satisfaction with life among different groups of elite athletes during a selected period of the COVID-19 pandemic and examine how COVID-19 related consequences were associated with these variables.DesignCross-sectional data collection during a selected period of the COVID-19 pandemic in Norway.Participants378 elite athletes, mean age 26.86 (range 18–59), 159 females and 219 males, divided into Olympic-level and Paralympic-level athletes (n=194) and elite and semielite athletes (n=184).Main outcome measuresHopkins Symptoms Check List − 10; symptoms of anxiety and depression; Bergen Insomnia Scale; Eating Disorder Examination Questionnaire Short; Canadian Problem Gambling Index and Satisfaction with Life Scale. In addition, we included specific COVID-19 questions (eg, financial concern, keeping daily routines, perceived coping and motivation).ResultsSymptoms of insomnia (38.3%) and depression (22.3%) were most prevalent within the sample. Symptoms of eating disorders more prevalent among female athletes (8.8% vs 1.4%) while symptoms of gambling problems were higher among male athletes (8.6% vs 1.3%). Olympic and Paralympic athletes reported lower levels of anxiety and depression symptoms than elite and semielite athletes. Financial concerns were associated with an increased risk of mental health problems, while daily routines and perception of coping were associated with less mental health problems and higher satisfaction with life.ConclusionSymptoms of insomnia and depression were the two most common mental health problems reported during this selected phase of the COVID-19 pandemic. Elite and semielite athletes reported financial concerns as a risk factor for mental health problems at a larger degree than Olympic and Paralympic athletes.
Relative survival after aortic valve surgery in patients with bicuspid aortic valves
Authors: Glaser Natalie , Jackson Veronica , Eriksson Per , Sartipy Ulrik , Franco-Cereceda Anders 
Published: February 2021

ObjectivesThe objective of this cohort study was to analyse long-term relative survival in patients with bicuspid aortic valve (BAV) who underwent aortic valve surgery.MethodsWe studied 865 patients with BAVs who participated in three prospective cohort studies of elective, open-heart, aortic valve surgery at the Karolinska University Hospital, Stockholm, Sweden, between 2007 and 2020. The expected survival for the age, sex and calendar year-matched general Swedish population was obtained from the Human Mortality Database. The Ederer II method was used to calculate relative survival, which was used as an estimate of cause-specific survival.ResultsNo differences were found in the observed versus expected survival at 1, 5, 10 or 12 years: 99%, 94%, 83% and 76% vs 99%, 93%, 84% and 80%, respectively. The relative survival at 1, 5, 10 and 12 years was 100% (95% CI 99% to 100%), 101% (95% CI 99% to 103%), 99% (95% CI 95% to 103%) and 95% (95% CI 87% to 102%), respectively. The relative survival at the end of follow-up tended to be lower for women than men (86% vs 95%). The mean follow-up was 6.3 years (maximum 13.3 years).ConclusionsThe survival of patients with BAV following aortic valve surgery was excellent and similar to that of the general population. Our results suggest that the timing of surgery according to current guidelines is correct and provide robust long-term survival rates, as well as important information about the natural history of BAV in patients following aortic valve surgery.
Comparison between 1973 and 2004/2016 WHO grading systems in patients with Ta urothelial carcinoma of urinary bladder
Authors: Collà Ruvolo Claudia , Würnschimmel Christoph , Wenzel Mike , Nocera Luigi , Califano Gianluigi , Tian Zhe , Shariat Shahrokh F , Saad Fred , Chun Felix K H , Briganti Alberto , Verze Paolo , Imbimbo Ciro , Mirone Vincenzo , Karakiewicz Pierre I 
Published: February 2021

AimsTo compare the 1973 WHO and the 2004/2016 WHO grading systems in patients with urothelial carcinoma of urinary bladder (UCUB), since no consensus has been made which classification should supersede the other and since both are recommended in clinical practice.MethodsNewly diagnosed patients with Ta UCUB treated with transurethral resection of bladder tumour were abstracted from the Surveillance, Epidemiology and End Results database (2010–2016). Kaplan-Meier plots and multivariable Cox regression models (CRMs) tested cancer-specific mortality (CSM), according to 1973 WHO (G1 vs G2 vs G3) and to 2004/2016 WHO (low-grade vs high-grade) grading systems.ResultsOf 35 986 patients, according to 1973 WHO grading system, 8165 (22.7%) were G1, 17 136 (47.6%) were G2 and 10 685 (29.7%) were G3. According to 2004/2016 WHO grading system, 24 961 (69.4%) were low-grade versus 11 025 (30.6%) high-grade. In multivariable CRMs, G3 (HR: 2.05, p<0.001), relative to G1, and high-grade(HR: 2.13, p<0.001), relative to low-grade, predicted higher CSM. Conversely, G2 (p=0.8) was not an independent predictor. The multivariable models without consideration of either grading system were 74% accurate in predicting 5-year CSM. After addition of 1973 WHO or 2004/2016 WHO grade, the accuracy increased to 76% and 77%, respectively.ConclusionsFrom a statistical standpoint, it appears that the 2004/2016 WHO grading system holds a small, although measurable advantage over the 1973 WHO grading system. Other considerations, such as intraobserver and interobserver variability may represent an additional matric to consider in deciding which grading system is better.
Diagnostic criteria for constitutional mismatch repair deficiency (CMMRD): recommendations from the international consensus working group
Authors: Aronson Melyssa , Colas Chrystelle , Shuen Andrew , Hampel Heather , Foulkes William D , Baris Feldman Hagit , Goldberg Yael , Muleris Martine , Wolfe Schneider Kami , McGee Rose B , Jasperson Kory , Rangaswami Arun , Brugieres Laurence , Tabori Uri 
Published: February 2021

BackgroundConstitutional mismatch repair deficiency syndrome (CMMRD) is the most aggressive cancer predisposition syndrome associated with multiorgan cancers, often presenting in childhood. There is variability in age and presentation of cancers and benign manifestations mimicking neurofibromatosis type 1. Genetic testing may not be informative and is complicated by pseudogenes associated with the most commonly associated gene,PMS2. To date, no diagnostic criteria exist. Since surveillance and immune-based therapies are available, establishing a CMMRD diagnosis is key to improve survival.MethodsIn order to establish a robust diagnostic path, a multidisciplinary international working group, with representation from the two largest consortia (International Replication Repair Deficiency (IRRD) consortium and European Consortium Care for CMMRD (C4CMMRD)), was formed to establish diagnostic criteria based on expertise, literature review and consensus.ResultsThe working group established seven diagnostic criteria for the diagnosis of CMMRD, including four definitive criteria (strong evidence) and three likely diagnostic criteria (moderate evidence). All criteria warrant CMMRD surveillance. The criteria incorporate germline mismatch repair results, ancillary tests and clinical manifestation to determine a diagnosis. Hallmark cancers for CMMRD were defined by the working group after extensive literature review and consultation with the IRRD and C4CMMRD consortia.ConclusionsThis position paper summarises the evidence and rationale to provide specific guidelines for CMMRD diagnosis, which necessitates appropriate surveillance and treatment.
Changes in work and life patterns associated with depressive symptoms during the COVID-19 pandemic: an observational study of health app (CALO mama) users
Authors: Sato Koryu , Sakata Ryohei , Murayama Chiaki , Yamaguchi Mai , Matsuoka Yoko , Kondo Naoki 
Published: February 2021

BackgroundDuring the COVID-19 pandemic, many people refrained from going out, started working from home (WFH), and suspended work or lost their jobs. This study examines how such pandemic-related changes in work and life patterns were associated with depressive symptoms.MethodsAn online survey among participants who use a health app called CALO mama was conducted from 30 April to 8 May 2020 in Japan. Participants consisted of 2846 users (1150 men (mean age=50.3) and 1696 women (mean age=43.0)) who were working prior to the government declaration of a state of emergency (7 April 2020). Their daily steps from 1 January to 13 May 2020 recorded by an accelerometer in their mobile devices were linked to their responses. Depressive symptoms were assessed using the Two-Question Screen.ResultsOn average, participants took 1143.8 (95% CI −1557.3 to −730.2) fewer weekday steps during the declaration period (from 7 April to 13 May). Depressive symptoms were positively associated with female gender (OR=1.58, 95% CI 1.34 to 1.87), decreased weekday steps (OR=1.22, 95% CI 1.03 to 1.45) and increased working hours (OR=1.73, 95% CI 1.32 to 2.26). Conversely, starting WFH was negatively associated with depressive symptoms (OR=0.83, 95% CI 0.69 to 0.99).ConclusionsDecreased weekday steps during the declaration period were associated with increased odds of depressive symptoms, but WFH may mitigate the risk in the short term. Further studies on the longitudinal effects of WFH on health are needed.