bluuebunny/crossref_metadata_2025_split huggingface dataset:
Las buenas prácticas de manufactura
Authors: Sánchez Vásquez Viviana Lorena 
Published: June 2021

En el siguiente trabajo se plantean de forma breve pero clara los pasos o principios básicos a considerar para la implementación de un eficiente plan de Buenas Prácticas de Manufactura que garantice alcanzar productos de calidad con el fin de toda empresa, la aceptación y sobre todo la satisfacción de sus clientes.Las BPM comprenden el conjunto de normas a implementar para garantizar la optimización de los procesos de una empresa sea de consumo alimenticio, empresas farmacéuticas, empresas inclinadas al ámbito de la medicina, u otras empresas afines.El Aseguramiento de la Calidad se trata de tener bajo control todo el proceso productivo, esto es, desde antes del ingreso de los insumos y materias primas a la empresa (control de proveedores), durante el proceso mismo de producción (documentación y controles en proceso) y después del mismo (control de almacenamiento, transporte y distribución), es decir en cada eslabón de la cadena de producción del producto.El primer paso hacia la implementación de este tipo de sistemas es la aplicación de ciertos criterios que, aunque mínimos, nos aseguran que los productos son elaborados de manera segura y con una calidad apropiada al uso que se les dará. De esto tratan las Buenas Prácticas de Manufactura (BPM).
Modelo de evaluación de indicadores de eficiencia energética en sistemas de aire acondicionado utilizando plataforma android
Authors: López Telenchana Luis Stalin , Serrano Castillo Byron Jesús 
Published: June 2021

El presente trabajo de investigación propone un modelo de evaluación de indicadores de eficiencia energética, que permita a la población decidir el uso racional de la energía utilizada en los aires acondicionados de uso masivo en la Provincia de Orellana. La investigación desarrollará una aplicación móvil sobre plataforma Android que facilite la visualización de dichos indicadores, y sensibilizar a la población sobre los niveles de eficiencia energética y su impacto en la economía y el medio ambiente.El desarrollo de la investigación incluye la documentación y análisis de los parámetros de entrada relacionados al diseño del sistema, además de la arquitectura Android y los argumentos calculados para dichos indicadores impuestos en la aplicación. Con esto se llega a la mayoría de la población aprovechando la alta demanda en los dispositivos móviles, y cumplir el objetivo de sensibilizar una cultura energética y una cultura ambiental en Orellana.
Psoriasis pustulosa generalizada de von zumbusch: Reporte de un caso
Authors: Aguayo Moscoso Santiago Xavier , Vélez Páez Jorge Luis , Irigoyen Mogro Estefanía Belén , Heredia Toledo Milagros Esthela , Morocho Jaramillo Pablo René , Paredes López Miguel Ángel 
Published: June 2021

La psoriasis pustulosa generalizada conocida como enfermedad de Von Zumbusch, es una enfermedad dermatológica poco frecuente de origen genético que se expresa por una respuesta inflamatoria exagerada, constituyendo una patología con alta morbilidad y potencialmente mortal, caracterizada por infiltración episódica de neutrófilos en la piel, desarrollo de pústulas, eritema generalizado y descamación. Presentamos el caso de una paciente que ingresó al servicio de terapia intensiva con lesiones dérmicas características de una enfermedad cutánea neutrofílica con fallo multiorgánico que no obedece a etiología infecciosa y con respuesta favorable a tratamiento con inmunomoduladores.
Determinantes sociales de la salud y la virulencia del covid-19 en Guayaquil
Authors: Velásquez Serra Glenda Coromoto , Mera Flores Liz Nathaly , Preciado Velásquez Oscar Eduardo , Barrera Reyes Christopher George 
Published: June 2021

Los determinantes sociales de la salud, (DSS) se definen como las circunstancias en que las personas nacen, crecen, trabajan, viven y envejecen. Influyen sobre las condiciones de la vida cotidiana. Objetivos: identificar las variables ambientales, biología humana, los estilos de vida y como los sistemas de salud impactaron en la calidad de vida de las personas, durante la pandemia de CoVID-19 en la ciudad de Guayaquil. Metodología: Corresponde a una revisión descriptiva de campo, documental, no experimental de corte transversal. Realizada en el lapso de marzo a julio de 2020. Para ello, se cotejó la situación de los DSS presentes durante la pandemia. Consideró referencias bibliográficas proveniente de la OMS/OPS recolectadas en el transcurso de la emergencia sanitaria, en diversos países y en América Latina, páginas oficiales del Ministerio de Salud del Ecuador, comunicados de prensa regionales y nacionales. Resultados: en el periodo de estudio, la temperatura y humedad fue de 28-34ºC y 95-99%, respectivamente. 71% de los guayaquileños se autodefinen como mestizos, 30.1% de la población tiene menos de 15 años, mientras, que el 5.9% de la población, mayores de 65 años. El virus afectó principalmente a la población adulta. El trabajo informal ocupa 37.9%. La educación privada reanudó sus actividades antes que la educación fiscal. Se destaca el uso de arroz en dos comidas diarias, patatas y fideos aunado a la cultura de freír la mayoría de los alimentos a consumir. 7.1-7.8% de la población ecuatoriana presenta diabetes y alrededor de 50-60% de la población muestra algún grado de obesidad. Se encontró 66.1% de los decesos fue por enfermedades isquémicas cardíacas Conclusiones: Los determinantes señalados favorecieron a la propagación de la pandemia, obliteró además como a nivel mundial, al colapso del sistema de salud ecuatoriano.
PENGARUH STRUKTUR KEPEMILIKAN ASING DAN KUALITAS AUDIT TERHADAP NILAI PERUSAHAAN DENGAN MANAJEMEN LABA SEBAGAI MEDIASI
Authors: Sri Hardyanti Budiman  , Randa Fransiskus , Bernadeth Tongli  
Published: June 2021

This study aims to examine the effect of foreign ownership structure and audit quality on firm value with earnings management as mediation. The population used in this study are all companies listed on the Indonesia Stock Exchange (IDX) with the research period of 2013-2018. The method of determining the sample using non-random sampling i.e purposive sampling and uses secondary data in the form of annual reports and financial statements of the company. The analytical methods used are path analysis and simultaneous test (F test). The results showed that the foreign ownership structure has a negative and significant effect on earnings management, audit quality has a negative and insignificant effect on earnings management, foreign ownership structure has a positive and insignificant effect on firm value, audit quality has a positive and significant impact on earnings management. firm value, and earnings management have a positive and significant effect on firm value. This study also found that foreign ownership structure has an indirect effect on firm value through earnings management and audit quality has an indirect effect on firm value through earnings management.
Application Enzymatic Method for Analysis Vaginal Tabletas “Fluomizin”
Authors: Vasilivna Koval'ska Olena , Mykola Blazheyevskіy 
Published: June 2021

Introduction: Development of a new enzymatic kinetic-photometric method for analysis of Dequalinium chloride, based on the use of enzymatic hydrolysis of acetylcholine, for determine the amount of Dequalinium chloride in the vaginal tablets “Fluomizin” No 6.
Method: The amount of Dequalinium chloride (DCh) was determined by the degree of inhibition of the enzymatic reaction, which was evaluated by the residual unreacted substrate - acetylcholine. Determination of the residual amount of acetylcholine in the reaction mixture was performed by a kinetic-photometric method using an indicator oxidation reaction of p-phenetidine with peracetic acid, which is formed during the auxiliary reaction of perhydrolysis with addition of excess hydrogen peroxide in the reaction mixture over a period of time.
Results: Optimal conditions were determined: pH 8.35 was selected, influence of nature of buffer solution, concentration of acetylcholine (0.05 mg / ml), cholinesterase (0.4 mg / ml), hydrogen peroxide (10,0%) and p-phenethedine (1 %), the incubation time (10 min).
Conclusions: The procedure for determination of Dequalinium chloride content in the vaginal tablets “Fluomizin” No 6 was developed. The kinetic parameters Km (Michaelis–Menten constant) and Vmax (maximal velocity) were determined.
La canción popular como fundamento del aprendizaje musical: el caso de Mallorca
Authors: Reynés Florit Arnau , Gelabert Gual Llorenç 
Published: June 2021

Grandes pedagogos musicales del siglo XX no han dudado en hacer de la música y canción tradicionales o populares el punto de partida de la enseñanza musical en los más pequeños. El húngaro Zoltan Kodály, como máximo exponente de esos postulados, argumenta la fácil asimilación del hecho musical por parte del niño a partir de aquello que le es más propio, aquello que ha oído y vivido en su entorno. Sin querer profundizar en demasía en las ideas de Kodály, tema ampliamente estudiado, analizaremos las aportaciones de tres figuras musicales de la Mallorca contemporánea: Bernat Julià, Antoni Martorell i Baltasar Bibiloni. Los tres coinciden en el uso de la canción popular mallorquina como base de sus composiciones en algún momento de sus respectivas trayectorias. Si bien los dos primeros enfocaron ese elemento a la composición de adaptaciones de nivel elemental y medio para el estudio del piano, Bibiloni lo trasladó al ámbito escolar en forma de arreglos vocales a una, dos o tres voces, para voces e instrumental Orff o para voces y piano, etc. Con este artículo pretendemos analizar y sacar a la luz todas esas aportaciones desde la realidad que les unió a los tres, su tierra natal, Mallorca.
VARIOUS TERMS OF CERTIFICATION PROGRAM LAND MASS , IDE AN IMAGE OR SEIZURE
Authors: Heryana H. Sudri 
Published: June 2021

ABSTRACT People rights enforcement is the duty of the executive officers from the function of government institutions in carrying out its duties and functions. Similarly, Agrarian Institution / BPN in serving the public in the land field of this country. Remembering its strategic program referred to, in the implementation of agrarian involves officials from the center to the following areas Governor, the Regent, Mayor, Head of sub district and villages officials. Besides to support the success of this activities, also involved the Agricultural Special Teams arrangement involve Opstib membership as a security element which at that time was very well respected in the main settlement of land disputes. PRONA. Prona is a program that can be categorized as a flagship program of Agrarian / BPN service to the people, because as an early breakthrough for the sake of upholding the rights on public land with the concept of fast, accurate and simple. As a national movement, this program is called flagship program remembering in this concept of specificity in service. Keywords: Land Certification, Prona, Scramble Image
INTELKAM UNIT ROLE IN COMBATING NARCOTICS ABUSE IN BOGOR BY DECREE NO NATIONAL POLICE SKEP / 37 / I / 2005 (Studies In Bogor City Police)
Authors: Suhartini1 Endeh , Rahmat Ade , Yumarni Ani 
Published: June 2021

ABSTRACT In the Decree of the Chief of Police No. Pol Skep / 37 / I / 2005 dated January 31, 2005 on Guidelines for Environmental Security Intelligence at the Indonesian Police, stated that security intelligence is intelligence that is implemented in carrying out the principal task of the police to bring internal security. Implementation of the activities and operations of security intelligence is to early prevention, early detection and implementation of early warning in accordance with the vision and mission of the security intelligence. Throughout 2014 the number of drug cases occurring among drug cases increased from 108 cases to 168 cases or by 55.6 percent.The objectives to be achieved in this thesis are: 1) To determine and analyze the role of Unit Intelkam in combating drug abuse in the city of Bogor by the Decree of the Chief of Police No. Skep / 37 / I / 2005. 2) To know and analyze the obstacles encountered Intelkam Force in combating drug abuse in the city of Bogor, and 3) To know and analyze the efforts made Intelkam Unit in overcoming obstacles to overcome combating abuse of narcotics in the city of Bogor. The method used normative juridical research method that is conceived as the norm of law, rules, principles or dogmas.The study concluded that the role of Bogor City Police Intelkam has shown good performance in dealing with drug abuse in the region combating the city of Bogor this is done in order to get results and optimum efficiency in the process of investigating criminal cases by way of supervision open or closed in preventing abuse of the use of narcotics.
Düzeltme: Yeni Medya ve Temsil: İnternet Gazeteciliğinde Toplumsal Cinsiyet Kimliklerinin Sunumu
Authors: SÖĞÜT Fatih , İLHAN Vahit 
Published: June 2021

İnternetin hayatımıza girmesiyle birlikte pek çok alanda olduğu gibi habercilik pratiklerinde de önemli değişimler olmuştur. İnternet gazetesi denilen çevrimiçi habercilik yapmaya imkân tanıyan yeni bir medya türü ortaya çıkmıştır. Bu çalışmada yeni bir medya türü olarak görülen internet gazetesi ve temsil konu edilmiştir. Özellikle internet gazetelerinde cinsiyet kimliklerinin nasıl inşa edildiği sorusuna cevap aranmaktadır. Bu çalışma kapsamında, internet gazetelerinde cinsiyet kimliklerinin görünürlük seviyesini, hangi cinsiyetin ne ölçüde görünür kılındığını ve nasıl görüntülendiğini tespit etmek üzere nitel içerik çözümlemesi yapılmıştır. Bu çalışma kapsamında sistematik yöntemle seçilen örneklemin belirlenmesinde kullanılan ölçüt internet gazetelerinin tıklanma sayısı olup, tıklanma bilgileri internet reyting verilerini yayınlayan Alexa.com adlı siteden alınmıştır. Bu doğrultuda, tıklanma sayısı en fazla olan ilk üç internet sitesi belirlenmiştir. Bu siteler, tıklanma sayısı sırasıyla “milliyet.com.tr”, “hurriyet.com.tr” ve “sabah.com.tr” dir. Elde edilen araştırma bulgularına göre kadın kimliğinin internet gazetelerinde daha çok magazin malzemesi olarak kullanıldığı, aynı zamanda bu eğilim sonucunda, internet gazetelerinde ağırlıklı olarak eğlence sektöründe yer alan 20-35 yaş arası kadınların görünür kılındığı tespit edilmiştir. İncelenen internet gazetelerinde ön plana çıkan erkeğin temsil özellikleri; modayı ve teknolojik gelişmeleri takip eden, delikanlı, baba ve eş, sert, dayanıklı, güçlü erkek şeklinde belirginleşmiştir ve ataerkil düzendeki erkek egemenliği bu temsil özellikleriyle meşrulaştırılmıştır.Bu makalenin ilk hali 30-06-2019 tarihinde yayınlandı. https://dergipark.org.tr/tr/pub/akil/issue/47030/531977
Comparison of Thermo-physical Properties of Mg-Ga and Mg-Pb Alloys at 1000 K
Authors: Panthi N. , Bhandari I. B. , Pangeni R. C. , Koirala I. 
Published: June 2021

Concentration-dependent thermophysical properties of molten Mg-Pb and Mg-Ga alloys at 1000 K was compared using the Redlich Kister equation by optimizing exponential interaction energy parameters based on the R-K polynomials framework. The mixing behavior was investigated by giving more emphasis to the role of temperature-dependent interaction energy parameters. Our study shows that the magnesium gallium alloy is slightly interacting than the magnesium lead alloy. The surface tension and viscosity of both alloys was compared using the Butler equation as improved by Kaptay and KRP (Kozlov-Ronanov-Petrov) approach respectively. The surface tension of Mg-Pb liquid alloy increases but decreases in Mg-Ga alloy with an increase in the concentration of Mg. The viscosity has a nonlinear variation for both alloys with the increase in the concentration of magnesium.
ESTUDO GENÉTICO-POPULACIONAL DOS SISTEMAS SANGUÍNEOS ABO E RH DE ALUNOS DO ENSINO MÉDIO DE PARANAÍTA, MATO GROSSO
Authors: Cuchi Giovana , Cardoso Elisa dos Santos , Rossi Ana Aparecida Bandini , Karina Gorini Luciane Karina 
Published: June 2021

Resumo: O conhecimento sobre os tipos sanguíneos ABO e Rh é muito relevante para casos de atendimento emergencial e aconselhamento sobre a doença hemolítica perinatal (DHP), bem como para a conscientização quanto à importância da doação de sangue. Considerando que, em Mato Grosso, a lei nº 9.905, de 06 de maio de 2013, determina que as escolas incluam informações sobre os tipos sanguíneos dos alunos na ficha de matrícula, este trabalho teve por objetivo realizar o estudo genético-populacional dos sistemas sanguíneos ABO e Rh de alunos do ensino médio da Escola Estadual João Paulo I, Paranaíta, Mato Grosso. Para obtenção dos dados, os alunos responderam anonimamente à um questionário com quatro questões fechadas. As respostas foram tabuladas e, a partir delas, foram obtidas as frequências fenotípicas, alélicas e genotípicas. Dentre os alunos que souberam informar o grupo sanguíneo, predominam os grupos sanguíneos A+ e O+, com 30,5% cada, seguidos dos indivíduos portadores de sangue O- (16,90%), considerado doador universal. Também foi possível identificar que, aproximadamente, 16% dos indivíduos do gênero feminino são Rh-, demonstrando a necessidade de que as escolas trabalhem os temas relacionados aos tipos sanguíneos, levando em consideração as problemáticas decorrentes da incompatibilidade sanguínea, seja em transfusão seja materno-fetal, bem como a importância da doação de sangue.
Palavras-chave: Doença Hemolítica Perinatal. Frequência Genotípica. Genética Populacional. Transfusões Sanguíneas.
Management challenges associated with a pineal region chordoma: illustrative case
Authors: Kwon Ji-Eyon , Ji So Young , Hwang Kihwan , Lee Kyu Sang , Choe Gheeyoung , Kim Chae-Yong , Han Jung Ho 
Published: June 2021

BACKGROUND
Chordomas, which are rare malignant neoplasms arising from notochordal remnants, often cause gradually progressive clinical symptoms. Intradural cranial chordomas (ICCs) are extremely rare and generally have a favorable prognosis. However, the authors reported the case of a primary ICC originating in the pineal gland presenting with recurrent thalamic hemorrhage and displaying an aggressive postoperative clinical course.

OBSERVATIONS
A 41-year-old man arrived at the emergency department with morning headaches and recurrent syncope that had lasted several months. Computed tomography and magnetic resonance imaging (MRI) revealed a pineal gland mass causing obstructive hydrocephalus and a subacute hematoma in the right thalamus. Three weeks after an endoscopic third ventriculostomy was performed, recurrent hemorrhage was observed in the right thalamus. The tumor was promptly removed surgically. The yellowish-white tumor did not exhibit abundant bleeding. No evidence of intratumoral hemorrhage around the hematoma pocket was found. Histopathological examination revealed the characteristics of a chordoma with minimal vascularity. MRI performed 10 weeks postoperatively for worsening headaches revealed abnormal enhancement of multiple cranial nerves, suggesting leptomeningeal seeding (LMS) of the tumor.

LESSONS
Despite radiotherapy and intrathecal chemotherapy, the patient’s neurological status worsened; he died 2 years postoperatively. A pineal ICC may cause recurrent thalamic hemorrhage and potentially fatal LMS, even in the early postoperative period.
Tethered brain: disentangling unintentional brain-mesh interfaces. Illustrative case
Authors: Spellicy Samantha E. , Kilianski Joseph R. , Poston Rachel , Moore-Hill Debra , Vale Fernando L. 
Published: June 2021

BACKGROUND
Surgical meshes have found widespread use in neurosurgical practice. While commonly recognized risks of synthetic mesh include infection, exposure of mesh implants, and foreign body reaction, the risk of mesh tethering to neural structures is often overlooked.

OBSERVATIONS
The authors presented the first case, to their knowledge, of the disentanglement of mesh interfaced to cortical tissue. The patient, a 68-year-old woman, presented with severe intractable seizure disorder and worsening left hand function and incoordination after meningioma resection and cranioplasty 9 years earlier. Magnetic resonance imaging (MRI) demonstrated interval progression of macrocystic encephalomalacia involving the right supplementary motor area, with fluid-attenuated inversion recovery signal extending posteriorly into the right primary motor cortex. Both computed tomography and MRI suggested potential tethering of the cortex to the overlying cranioplasty mesh. Because of the progressive nature of her condition, the decision was made to surgically remove the tethered mesh.

LESSONS
De-tethering brain parenchyma from surgical mesh requires careful microdissection and judicious use of electrocautery to minimize further tissue damage and preserve neurological function. This inadvertent complication evinces the importance of using dural substitutes when unable to primarily repair the dura to prevent scarring and tethering of neural tissues to synthetic cranioplasty materials.
Short lever arm, bipedicular handlebar construct for correction of acute angular kyphosis in spondylodiscitis-induced kyphotic deformity: illustrative case
Authors: Huang Meng , Cajigas Iahn , Vanni Steven 
Published: June 2021

BACKGROUND
Pyogenic spondylodiscitis diminishes spinal structural integrity via disruption of the anterior and middle column, sometimes further compounded by iatrogenic violation of the posterior tension band during initial posterior decompressive surgeries. Although medical management is typically sufficient, refractory infection or progressive deformity may require aggressive debridement and reconstructive arthrodesis. Although anterior debridement plus reconstruction with posterior stabilization is an effective treatment option, existing techniques have limited efficacy for correcting focal deformity, leaving patients at risk for long-term sagittal imbalance, pain, and disability.

OBSERVATIONS
The authors present a case of chronic lumbar pyogenic spondylodiscitis in a patient in whom initial surgical debridement failed and pronounced angular kyphosis and intractable low back pain developed. A novel bipedicular handlebar construct was used to achieve angular correction of the kyphosis through simultaneous anterior interbody grafting and posterior instrumentation with the patient in the lateral position.

LESSONS
Leveraging both pedicle screws at the same level to transmit controlled corrective distraction forces through the segment allows for kyphosis correction without relying on long posterior constructs for cantilever reduction. Simultaneous anterior reconstruction with a posterior short lever arm, bipedicular handlebar construct is an effective technique for achieving high angular correction during circumferential reconstructive approaches to postinfectious focal kyphotic deformities.
Perencanaan Struktur Atas Jembatan Komposit Sungai Nipah Desa Darul Aman Kecamatan Rupat
Authors: Puluhulawa Indriyani , Aspaliza Nur , Armada Armada 
Published: June 2021

The Darul Aman Village Bridge was originally a wooden bridge connecting community settlements with harbor and plantation areas. Yhe current condition of the bridge is not worth crossing because the wooden structure on the bridge has severe weathering, so it is very risky if forced to pass through the vehicle continuously and will cause further damage.for this purpose a nwe bridge is planned using a composite structure between steel girder and concrete slab. This plan refers to SNI T-02-2005 for loading bridge and SNI T-03-2005 fot steel structure planning. The planned plan includes bridge slab, girders, diaphragms and bridge elastomeric placement.
From the result of the planning, the steel girder profile is using WF 800.300.14.26 , with a gap between 1,125 m. The steel angles profile diaphragm 70.70.7 mm using with a gap 4 m diaphragm, the elastomeric placement diameter is 175.175.12 mm