bluuebunny/crossref_metadata_2025_split huggingface dataset:
Curative impacts of Ethanoic Extract of Laportea aestuans (L) Chew in Aspirin-Induced Ulcerative compromise in Male Rats
Authors: Akinwande Onadeko , Olusegun Akinola 
Published: October 2021

Toxicity of Non-steroidal anti-inflammatory drugs (NSAIDs) are being reported with its diverse effect in the host resulting in ulcerations. Ulceration was induced orally using aspirin. Twenty-four male Wistar rats were used for this study (120-150g). Rats were divided into 6 groups with each group containing 4 rats. Rats were pre-treated orally with cimetidine, a reference drug. Group 1 rats orally received 1% gum acacia solution as the control group, Group 2 rats orally administered 25 mg/kg aspirin and served as the ulcerated, untreated group, rats in groups 3 and 4 were pre-treated orally with 200 mg/kg and 400 mg/kg respectively for 3 days while rats in groups 5 and 6 were pre-treated orally with 50 mg/kg cimetidine and 50 mg/kg catechin respectively for 3 days. The result of this study shows that the ulcerated, untreated rats showed increased concentrations of The result of this study shows that the ulcerated, untreated rats showed increased concentrations of acid output, pepsin activity with a concomitant decrease in pH values, and mucin content compared to control group but pre-treatment with different doses, cimetidine and catechin reversed these observations. Activities of superoxide oxidase were decreased in the ulcerated, untreated group with a concomitant increase in lipid peroxidation concentration but pre-treatment with different doses, cimetidine and catechin reversed these observations. In conclusion, the ethanoic extract of L. aestuans can be said to be used therapeutically agaisnt aspirin-induced gastric ulcer which is due to the presence of bioactive compounds in the plant.
as an anti-ulcerogenic agent against aspirin-induced gastric ulcer which is due to the presence of phytochemicals in the plant.
Keywords: Ulcerations, bioactive compounds, oxidative stress, superoxide dismutase, aspirin
Stability and Degradation Kinetic study of Bilastine in Solution State by RP-HPLC Method
Authors: Gupta Krishna R , Tembhare Ekta P , Ganorkar Anvesha V , Karemore Heera , Umekar Milind J 
Published: October 2021

Aim: The current study dealt with the degradation behavior of Bilastine and degradation kinetics of a drug in solution state. Background: Very limited information on the effect of pH on maximum stability has been published. In order to understand the degradation kinetics of bilastine, aqueous stability studies were carried out, because such studies on bilastine have not been reported in the literature, further no methods have reported about shelf-life determination of bilastine. The study design involves selection of stability indicating RP-HPLC method for estimation of drug then evaluation of degradation kinetics, shelf-life determination and validation of proposed method. Results: The Shimadzu HPLC series 1100 was used for stress degradation analysis of bilastine in tablet dosage form. The analysis was performed using Agilent ZORBAX SB-C8 (4.6×150×5µm) column and Phosphate Buffer: Acetonitrile (pH-5.0) in the ratio of 60:40 as mobile phase; wavelength selected for analysis was 254nm with the flow rate of 1mL/min at which drug showed sharp peak. The analysis was performed on the isocratic pump mode with the injection volume of 20µl. The mobile phase is used as diluent. The proposed method was found to be linear over the range 10 to 50 µg/mL. The analysis was performed by placing standard and samples with 7 different pH buffer, oxidative and neutral hydrolytic solutions in oven at 40ºC, 60⁰C and room temperature for an interval of 30, 60, 90, 120, 150, 180 mints for standard and samples. The results indicated that the pH, temperature, ionic strength and oxidation greatly influence the stability of Bilastine and the degradation behavior of Bilastine followed pseudo-first-order kinetics. Bilastine was most stable in neutral, alkaline, lower temperature conditions and lower ionic strength. Conclusion: The proposed method was found to be specific, selective and robust and successfully applied for its assay, degradation (stress testing) of drug and degradation kinetics in solution state.
Keywords: Degradation, Stability, Bilastine, RP-HPLC, Kinetics
DIPLOMASI EKONOMI JEPANG DALAM UPAYA PERPINDAHAN LIMBAH B3 MELALUI INDONESIA-JAPAN ECONOMIC PARTNERSHIP AGREEMENT (IJEPA)
Authors: Anggraeni Nurshinta Anggia 
Published: October 2021

<p><em>The development of Japan's industrial sector triggered the generation of toxic and hazardous waste as its consequences which endangered the environment and human’s health. The high cost of waste management and limited land disposal encourages transboundary movement to developing countries. Although it has been monitored by the Basel Convention which ban toxic waste movement, Japan still find the loophole by using Indonesia-Japan Economic Partnership Agreement (IJEPA) as an instrument to transfer domestic waste abroad. This study will use the theory of economic diplomacy and issue linkage concept to observe Japan's diplomacy in reaching an agreement on reducing toxic and hazardous waste tariff with Indonesia in IJEPA. The result shows that Japan bartered the issue by offering capacity building compensation. Those are consisting of investment on toxic and hazardous waste management facilities and the development of hazardous waste recycling market in Indonesia. Through the compensation, reduction tariff of hazardous waste could be achieved by Japan to continue its transboundary movement and reduce the impact of domestic environmental pollution, while still accommodating the interests of Indonesia in terms of capacity building towards hazardous waste management.</em></p>
KERJASAMA INTERNASIONAL OLEH PEMERINTAH DAERAH (STUDI KASUS: MEDAN-PENANG)
Authors: Sinambela Stivani Ismawira 
Published: October 2021

Kerjasama <em>Sister City</em> antara Pemerintah Kota Medan dengan Penang (Georgetown) di Malaysia terbentuk dari adanya kesamaan kultur dan etnisitas penduduknya yang ditandatangani sejak Oktober 1984 dengan harapan berkembangnya kerjasama di segala bidang. Penelitian ini dimaksudkan untuk mengetahui bagaimana Kerjasama Internasional yang dilakukan oleh Pemerintah Kota Medan dalam menjalankan kerjasama <em>Sister City</em> dengan Penang pada tahun 2010-2014. Metode penelitian yang digunakan penulis adalah metode deskriptif analitis, dengan tujuan untuk menggambarkan fakta yang berhubungan dengan masalah yang diteliti. Sebagian besar data yang dikumpulkan melalui studi kepustakaan, penelusuran data online, dokumentasi, wawancara dan observasi yang kemudian dianalisis dengan pendekatan: 1) <em>Decisions Making Process</em> yang merupakan proses awal yang dilakukan oleh Kepala Daerah sebelum memutuskan suatu tindakan. 2) <em>Paradiplomacy</em> yaitu diplomasi yang dilakukan oleh pemerintah sub-nasional di suatu negara dengan Pemerintah sub-nasional di negara lain. Hasil penelitian menunjukkan bahwa implementasi dari kewenangan pada Pemerintah Kota Medan dalam menjalankan hubungan luar negeri, kerjasama <em>Sister City</em> dengan Kota Penang adalah <em>MoU</em> yang telah disepakati bersama belum mengalami pembaharuan sejak tahun 1984, hal tersebut menunjukan adanya stagnansi pada hubungan kerjasama antara Pemerintah Kota Medan dengan Penang. Selain <em>MoU</em> yang tidak mengalami perubahan sejak disepakati oleh kedua belah pihak, terdapat beberapa hambatan yang terbagi menjadi dua, yaitu <em>External Government Issues</em> dan <em>Internal Government Issues</em>.
Analysis of Light Pollution as a Neglected issue in Development
Authors: Isnarti Rika 
Published: October 2021

<p><em>The growth of economy that encourage development sometimes cause damage to environment. One of the case is light pollution while many people do not realize this pollution is existed. This research analyses light as one kind of pollution that people tend to unrealize. It describes cause and effect of light pollution. This pollution occurs because overused and misdirected light. Moreover, economics growth and increasing of population encourage this phenomena. Further, It argues that light pollution gives bad impact to environment and animal as well as becomes a threat to human health. This research employs qualitative methods by collecting, categorizing data from library research. It found that light pollution give bad impact to environment and human health, such as miss direction in migration animals, we cannot see Milky Way, and potential breast cancer to human. In addition, light pollution also wastes of energy. So, more attention has to be paid to this pollution and several managements in development and regulation have to be taken to manage this pollution worse.</em></p><p><em> </em></p><p><em>Keywords: </em></p>
Quality of Life Score Difference Based on Chronic Otitis Media Outcome Test-15 (COMOT-15) Questionnaire on Chronic Supurative Otitis Media Patients with and without Cholesteatoma at Sanglah General Hospital
Authors: Setiawan E. P. , Meregawa M. R. R. D. 
Published: October 2021

Introduction: Chronic suppurative otitis media (CSOM) is a chronic infection in the middle ear with perforation of the tympanic membrane and persistent or intermittent secretion from the middle ear which is more than two months. It causes a pathological condition in the ear which results in limited hearing function in a person and will affect the quality of life of the patients. Quality of life assessment is carried out to assess the patient's condition and an instrument is needed to be able to evaluate the condition of CSOM patients. Currently, there are several questionnaires that can be used to assess the quality of life of people with CSOM. One of them is the Chronic Otitis Media Outcome Test (COMOT-15) which is a valid measuring tool to subjectively assess the quality of life of people with CSOM.
Methods: This study was an observational study with a cross sectional study design.
Results: There was a difference in quality-of-life scores between CSOM patients with and without cholesteatoma types with mean score 26.87 (95% CI 22.28- 31.47) (p<0.001).
Conclusion: There was a difference in quality-of-life scores between CSOM patients with and without cholesteatoma types at Sanglah General Hospital, Denpasar.
Role and Impact of Operating Theatre Background Music on Users and Patients: Opinion of Theatre Staff
Authors: Ijah Rex Friday Ogoronte A. , Elenwo Solomon N. , Dayi Joy O. , Aaron Friday E. , Oko-Jaja Rose E. , Ofuru Vitalis O. 
Published: October 2021

Aim: To determine the opinion of operating theatre users on the role of operating theatre background music on theatre users and patients in tertiary health care facilities in Port Harcourt.
Background: The relationship between music and health has been described by researchers. Music has been used in several hospital settings with effects which some consider beneficial and others harmful.
Materials and Methods: This cross-sectional descriptive study was carried out among theatre users from March to June 2020 in two multispecialty tertiary healthcare facilities in Port Harcourt Nigeria. Using the convenience sampling method, data collected with pretested semi-structured questionnaires were analyzed using the Statistical Package for the Social Sciences (SPSS) version 20.0.
Results: One hundred and twenty-one (82.9%) respondents asserted to knowledge of relationship between music and stress hormone. 97 (66.4%) agreed that music has positive effect on workers in the operating theatre. One hundred and seventeen (80.1%) respondents were of the opinion that background music in the operating theatre is not a distraction, while 22 (15.1%) respondents felt otherwise. One hundred and forty-four (98.8%) respondents agreed to usefulness of background music while at work. High proportion of respondents who lack knowledge of the relationship between stress hormone and music had no preference for operating theatre background music and the relationship was statistically significant (P<0.05).
Conclusion: Operating theatre background music is useful as opined by the majority of operating theatre staff, though its preference is low among those with less knowledge of the positive relationship between such music and stress hormones.
Analysis of the Key Factors for Successful Public Policy Implementation: A Qualitative Study in Slovenia
Authors: Kotnik Žiga , Umek Lan , Kovač Polonca , Stanimirović Dalibor , Vintar Mirko 
Published: October 2021

Abstract
This paper analyses the role and significance of the selected factors for the successful design and implementation of public policies in Slovenia and more broadly. Based on structured interviews and content analysis of the responses, we investigated the impact of predefined factors (i.e. strategic, institutional, normative, economic/financial, methodological/procedural, organisational/human resources/ICT support factors). The aim of the article is to analyse the case of Slovenia, to identify which factors contribute most to the successful design and implementation of public policies, and to provide a basis for comparison with similar countries or systems. The research findings imply several conclusions, particularly strategic factors, which have been identified as the most essential. The other findings are related to the lack of evaluation practice, the discontinuity of and early changes in government, which affect all aspects of policy execution and lead to poor intersectoral collaboration as well as insufficient and ineffective public debate. Not surprisingly, all of the identified hindrances are featured in the pertinent theories as necessary democratic dimensions of contemporary public governance. Contrary to the national context, the EU influence seems to expedite policymaking processes and contribute to the consistency of policies.
LOS ARCTIINI (LEPIDOPTERA, EREBIDAE, ARCTIINAE) ATRAÍDOS POR Heliotropium sp. (HELIOTROPIACEAE) EN LA ESTACIÓN BIOLÓGICA JOSÉ ÁLVAREZ ALONSO, IQUITOS, PERÚ
Authors: ANCAJIMA Georgette Paola , NEYRA-HIDALGO Diego Andrés 
Published: October 2021

Los árctinos son atraídos por plantas productoras de pirrolizidinas (ej. Heliotropiaceae), ya que emplean estos compuestos en las feromonas. La necesidad de este compuesto hace que las plantas secas de algunasHeliotropiaceae sean un eficiente método de colecta. Este estudio evaluó la riqueza de Arctiini con preferencia de Heliotropium sp. en la Estación Biológica José Álvarez Alonso, durante los meses de enero, febrero y marzo de 2014. Se establecieron 21 puntos de colecta, 14 puntos en bosque tropical y 7 en varillales. Fueron colectados 16 especies de Arctiini (39 ejemplares), distribuidos en las subtribus Arctiina, Ctenuchina y Euchromina. Los varillales mostraron mayor número de especies en relación a los bosques tropicales. Probablemente exista una preferencia por las hojas de Heliotropium sp. Todas las especies registradas son nuevos registros para la Estación Biológica José Álvarez Alonso, de los cuales, siete han sido exclusivamente registradas en los varillales. Se ha generado una base para futuros trabajos, es probable que estos bosques albergan un mayor número de especies, que podrían registrarse con mayor esfuerzo de muestreo y otros métodos de colecta. La lista presentada de la fauna de Arctiini sirve como soporte para la conservación de estos bosques.
ЗАСТОСУВАННЯ ІННОВАЦІЙНИХ ЗАСОБІВ НАВЧАННЯ В УМОВАХ СЬОГОДЕННЯ
Authors: Гончарова Євгенія , Бєляєва Олена 
Published: October 2021

У статті розглядається проблема оптимальної організації освітнього процесу, спрямованого на підготовку фахівців, мотиваційно-орієнтованих на безперервний процес активної пізнавальної діяльності. Аргументується закономірність комплексного застосування традиційних та інноваційних засобів навчання з метою отримання якісних змін у засвоєнні навчального матеріалу студентами, формуванні їх фахових компетентностей та стимулюванні пізнавальної активності.
Аналізується місце особистості викладача у процесі творчого поєднання традиційних та інноваційних засобів навчання з метою модернізації й інтенсифікації навчального процесу у сучасних ЗВО України.
KEPUTUSAN PENGAMBILAN KREDIT PEMILIKAN RUMAH (KPR) PENGARUH BRAND AWARENESS, PHYSICAL EVIDENCE DAN SERVICE QUALITY PADA PT. BTN (PERSERO) Tbk
Authors: Widyastuti Maria 
Published: October 2021

This research aims to determine the effect of brand awareness, physical evidence and service quality on mortgage decisions at Bank BTN Branch Office Surabaya Bukit Darmo. The sampling method are purposive sampling method with sample size of 100 respondents. The results showed that: (1) there is a positive and significant impact of brand awareness on the decisions to make KPR at Bank BTN Surabaya Bukit Darmo Branch office (2) There is a positive and significant effect of physical evidence on decision to make KPR at Bank BTN Surabaya Bukit Darmo Branch Office (3) there is a positive and significant effect of service quality on the decisions to make KPR at Bank BTN Surabaya Bukit Darmo Branch Office; and the regression coefficient is 0.314. (4) The influence of brand awareness, physical evidence and service quality on mortgage decisions at Bank BTN Surabaya Bukit Darmo Branch Office (adjusted R2) is 79.7%.
Saving Management in Malaysia
Authors: Murugiah Logasvathi 
Published: October 2021

Saving management is about empowering and enlightening consumers so that they are well prepared about finance in a way that is relevant to their lives. Koid (2008) denotes that challenges faced by Malaysian in disabling them to protect their finances are low level in mastering financial literacy, poor saving rates, complex products and services, access to a variety of financial products and costs of living. Savings can be lifesavers during an individual’s financial downturn. Today, financially we can be in a good position but nobody knows what will happen in the future. But one thing is for sure, our savings today would certainly save our financial pitfall in the future. Therefore, it is vital for an individual to empower themselves a good saving habit. Therefore, this paper endeavors to analyze the key determinants of saving management in Peninsular Malaysia. Survey forms were distributed to 2500 working adults in Peninsular Malaysia, ages ranging from 18 to 45 years old. Meanwhile, the method employed in this study is multiple regression analysis. Further, this study highlight that parents’ characteristic, investment skill, financial literacy and expenses management are the important factors in enhancing and increasing the level of saving skills in Malaysia.
Influence of Extension Connectivity on Youth Engagement into Paddy Farming in Kano State, Nigeria
Authors: Datti Muhammad Ibrahim , Said Rusmawati , Ismail Normaz Wana , Rehman Azmawani 
Published: October 2021

The international development agencies have made a clarion call to the developing countries, upon strengthening their agricultural sectors with a modern technological connectivity, so that massive unemployed youth can be employed in the sector. The insufficient of youth data and studies becomes a major challenge in these countries. However, emphasis of Nigeria’s government was more on the provision of farm inputs subsidies to farmers. While the policy on youth’s inclusion into paddy farming was not given much consideration, despite the growing number of unemployed youths. Also, the availability of paddy fertile land and increase in extension connectivity subscription in the country could have improve both the paddy production and youth employment. Yet over 33% of the youths are unemployed. Thus, designing an effective youth policy could not be realized without analysing factors that can inspire them to participate into farming. This study examines the effect of extension connectivity technology in influencing youth participation in paddy farming in Kano, Nigeria. The study selected 180 youth respondents from mixed sampling techniques and the questionnaire was administered in three paddies local government areas in Kano state around August 2019. The binary logit was used in the estimation of different models. The findings proved that extension connectivity used in farming can inspire youths to participate and remain in paddy farming. The study highlights the need for greater attention in utilising the extension connectivity in enlightening and educating youths to access information to aids paddy farming activities.
Credit-worthiness Prediction in Energy-Saving Finance Using Machine Learning Model
Authors: Sudarmaji Eka , Achsani Noer Azam , Arkeman Yandra , Fahmi Idqan 
Published: October 2021

Companies can form their own "ESCO model" with their capitals. Unfortunately, customer's creditworthiness was becoming more crucial for ESCO. Machine learning was used to predict the creditworthiness of clients in ESCO financing processes. This research aimed to develop a scoring model to leverage a machine learning and life cycle cost analysis (LCCA) to evaluate alternative financing for Energy Saving in Indonesia. The results of calculations using multinomial logistic regression showed that the accuracy value of prediction data with test data was 88.3562 %. The prediction rate result that refers to the percentage of correct predictions among all test data was 91.67%, and False Positive Rate (FPR) was 39.44%. The True Positive Rate was called Recall or 'Sensitivity Rate' as it was defined as several positive cases that were correctly identified (TPR) was 92.20%. We found the machine learning methods for creditworthiness prediction in retrofitting projects were fresh and worth a shot. It was hoped that this new practice would grow in popularity and become standard among ESCOs. Unfortunately, current machine-learning-based creditworthiness scoring practices lacked explain ability and interpretability. Unfortunately, ESCO must penalize the retrofitting project. As a result, since retrofitting was a new industry, the credit approval process was challenging to communicate to consumers. The most important thing for ESCO to deal with the project was to have a friendship and know-how with the client. Research from these case studies led to a clearer understanding of the factors affecting all parties' decisions to implement and continue with their ESCO project.
Assessment of a Hierarchical Model Using Partial Least Squares (PLS): The Case of Enterprise Resource Planning (ERP) System Continued Usage
Authors: Ramayah T. , May-Chiun Lo , Samad Sarminah , Ahmad Noor Hazlina , Halim Hasliza Abdul 
Published: October 2021

This paper is an empirical study that highlights the usage of Enterprise Resource Planning (ERP) system among individual users. Questionnaire survey was carried out with measures gleaned from the literature. In this study we have proposed and tested a hierarchical reflective model of quality unlike other studies. The results support the higher order hierarchical reflective model tested using the Partial least Squares (PLS) software of SmartPLS. We further found support for all the hypotheses developed. Quality was a significant predictor of continuance intention and satisfaction. Satisfaction also drives continuance intention and mediates the effect of quality on the continuance intention relationship. Implications of the findings are further explored.