bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cristianismo, sociedade brasileira e violência doméstica: faces desfiguradas e gritos de socorro na atualidade
Authors: Xavier Donizete José , Delfino Claudio Antônio , Reis Jerusa Lisboa Pacheco Reis Pacheco 
Published: October 2021

É notório em nossos dias o sofrimento do povo brasileiro, juntamente de toda a humanidade. Neste momento da história, todos são assolados com os dramas da Pandemia do novo Coronavírus. O silêncio angustiante e vazio rompido pelo choro e pelas lágrimas de poucos familiares sepultando seus mortos, milhares de famílias enlutadas pela morte de seus entes queridos, o sistema de saúde que nem sempre consegue atender às necessidades, principalmente as dos mais vulneráveis, a necessidade do isolamento social, e ainda, as consequências destes tempos pandêmicos que vão se aflorando, tais como o desemprego, a fome, a perda da esperança em dias melhores, são algumas marcas do sofrimento de muitos de nossos irmãos Brasil afora. Não bastasse isso, vai crescendo de maneira grave e vertiginosa, em meio a esse triste cenário, a violência doméstica. Tal fenômeno tem desfigurado o rosto de muitas crianças, adolescentes e mulheres, provocando gritos de socorro, provenientes de muitos lares anônimos, gritos que não podem cair no esquecimento nem na indiferença, quer seja do Cristianismo ou de qualquer outra Confissão Religiosa que tenham como pilares o amor a Deus e ao próximo. Toda pessoa de boa vontade da Sociedade Brasileira deve estar atenta aos pedidos de socorro oriundos desses gritos abafados. Diante disso, objetivou-se nesta reflexão verificar quais seriam os desafios atuais, especificamente para o Cristianismo e para a Sociedade Brasileira no combate à violência doméstica e como tornarem-se próximos dos que já são acometidos por tão grandes sofrimentos e tomar atitudes que previnam futuros horrores. Ao menos duas questões preliminares se fizeram necessárias: é legítima a prática de um modelo religioso cristão, tendo Jesus Cristo como fundamento, que se baseie na premissa, segundo a qual, se está bem para mim a situação, não importa como está a do outro? Seria razoável para qualquer pessoa de boa vontade e para uma sociedade inteira negligenciarem-se diante da desfiguração dos rostos e dos gritos de sofrimento de milhares de crianças, adolescentes e mulheres?
A Study on the Transcriptional Profile of NOS2 and IFN-γ Genes in River Buffalo with Endometritis
Authors: Othman Othman E. , M. Osman Noha , A. Abo El-Maaty Nadia , R. Mahfouz Eman 
Published: October 2021

Background and Aim: Uterine lumen contamination with bacteria is ubiquitous in buffalo after parturition. Nearly one-third of these infected animals develop endometritis which leads to reduced fertility. The present study aimed to evaluate the expressions of IFN-γ and NOS2 genes in uterine tissue of buffaloes with endometritis and comparing them with those in healthy animals using RT-qPCR
Materials and Methods: Uterine samples were collected from 50 apparently healthy and 50 clinically infected buffaloes. RNA was extracted from the collected buffalo's uteri and cDNA was synthesized from extracted RNA. Quantitative Real Time PCR technique was performed using this synthesized cDNA.
Results: Apparent up-regulation of both genes mRNA expression was recorded in endometritis-infected animals with 8.3-folds for IFN-γ and 9.99-folds for NOS2 (P<0.001).
Conclusion: The upregulation of IFN-γ and NOS2 expression in the uterine tissue of endometritis-infected buffaloes can be used as a scale for measuring the efficiency of drugs used for endometritis treatment.
Catalytic Decomposition of Methane to Hydrogen over Al2O3 Supported Mono- and Bimetallic Catalysts
Authors: Ergazieva Gaukhar E. , Makayeva Nursaya , Shaimerden Zhanna , Soloviev Sergiy O. , Telbayeva Мoldir , Akkazin Еrzhan , Ahmetova Fariza 
Published: October 2021

This article discusses the decomposition of methane in the temperature range 550–800 °C on low-percentage monometallic (Ni/g-Al2O3, Co/g-Al2O3) and bimetallic (Ni-Co/g-Al2O3) catalysts. It is shown that the bimetallic catalyst is more active in the decomposition of methane to hydrogen than monometallic ones. At a reaction temperature of 600 °C, the highest methane conversion is 81%, and the highest hydrogen yield of 51% is formed on Ni-Co/g-Al2O3. A complex of physicochemical methods (Scanning Electron Microscope (SEM), X-ray Diffraction (XRD), Temperature Programmed Reduction (TPR-H2), etc.) established that the addition of cobalt oxide to the composition of Ni/g-Al2O3 leads to the formation of surface bimetallic Ni-Co alloys, while the dispersion of particles increases and the reducibility of the catalyst is facilitated, which provides an increase in the concentration of metal particles - active centers, which can be the reason for an increase in the catalytic properties of a bimetallic catalyst in comparison with monometallic ones. Copyright © 2021 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
Precursor Engineering of the Electron Transport Layer for Application in High‐Performance Perovskite Solar Cells
Authors: Lin Zhichao , Zhang Wenqi , Cai Qingbin , Xu Xiangning , Dong Hongye , Mu Cheng , Zhang Jian‐Ping 
Published: October 2021

AbstractThe electron transport layer (ETL) is a key component of regular perovskite solar cells to promote the overall charge extraction efficiency and tune the crystallinity of the perovskite layer for better device performance. The authors present a novel protocol of ETL engineering by incorporating a composition of the perovskite precursor, methylammonium chloride (MACl), or formamidine chloride (FACl), into SnO2 layers, which are then converted into the crystal nuclei of perovskites by reaction with PbI2. The SnO2‐embedded nuclei remarkably improve the morphology and crystallinity of the optically active perovskite layers. The improved ETL‐to‐perovskite electrical contact and dense packing of large‐grained perovskites enhance the carrier mobility and suppress charge recombination. The power conversion efficiency increases from 20.12% (blank device) to 21.87% (21.72%) for devices with MACl (FACl) as an ETL dopant. Moreover, all the precursor‐engineered cells exhibit a record‐high fill factor (82%).
Functioning and well‐being in older children and adolescents with achondroplasia: A qualitative study
Authors: Pfeiffer Kathryn M. , Brod Meryl , Smith Alden , Viuff Dorthe , Ota Sho , Charlton R. Will 
Published: October 2021

AbstractThe study aimed to explore how having achondroplasia affects older children and adolescents' day‐to‐day functioning and well‐being. Individual/focus group interviews were conducted with older children/adolescents between the ages of 9 to <18 years and diagnosed with achondroplasia to elicit key concepts. An adapted grounded theory approach informed the qualitative analysis of interview data. Thirty‐two children and adolescents completed interviews. Study results revealed five impact domains, including physical health, functioning, school impacts, emotional well‐being, and social well‐being. Frequently reported impacts on physical health included low stamina/tiring easily (81%) and back pain (69%). Key impacts in the functioning domain were difficulty with reaching objects or high places (84%) and walking long distances (75%). Emotional impacts included feeling different (63%), worried/scared (47%), and embarrassed/self‐conscious (47%). Impacts on social well‐being included difficulty with sports or physical play (81%) and others treating child as younger than their actual age (75%). The most frequent school impact was trouble participating in physical education (81%). A preliminary theoretical model depicting the experiences of older children/adolescents with achondroplasia was constructed based on the analysis. The preliminary theoretical model of older children and adolescents' experiences of living with achondroplasia may be used to inform future research and clinical practice.
Techno‐economic assessment of bio‐refinery model based on co‐pyrolysis of cotton boll crop‐residue and plastic waste
Authors: Patel Himanshu , Maiti Pratyush , Maiti Subarna 
Published: October 2021

AbstractThis study evaluated the techno‐economic aspects of empty cotton boll valorization to liquid fuel (moisture free bio‐oil), potash fertilizer, and activated carbon. Three different plant capacities, in terms of feedstock handling capacities were considered: 50, 100, and 200 t day−1. For each plant capacity, three plant variants were considered: only fuel, fuel + potash fertilizer, and fuel + potash fertilizer + activated carbon. The net present value ranged from 7.73 M$ for a 50 t day−1 plant to 47.38 M$ for a 200 t day−1 plant, producing liquid fuel along with fertilizer and activated carbon. The overall profitability of the plant was improved by higher plant capacity. For a 200 t day−1 plant, equipment purchase cost related to the synthesis of fuel, potash fertilizer and activated carbon contributed 32.87, 25.77, and 41.36%, respectively to the total purchase equipment cost of the entire plant. Among the three products, activated carbon contributed 81.03% to the total revenue generated by the entire plant. The sensitivity of plant economics towards feedstock price, selling price of activated carbon, potassium hydroxide recovery, annual interest rates, and total capital investment was examined. The economic competitiveness for this kind of thermo‐chemical conversion was assessed in comparison with the solar gasification route. © 2021 Society of Chemical Industry and John Wiley & Sons, Ltd
Comparison of nucleoside and nucleotide analogs in the recurrence of hepatitis B virus‐related hepatocellular carcinoma after surgical resection: A multicenter study
Authors: Qi Weili , Shen Junyi , Dai Junlong , Wu Youwei , Zhang Yu , Leng Shusheng , Gao Fengwei , Ran Shun , Peng Wei , Zhang Xiaoyun , Wen Tianfu , Li Chuan 
Published: October 2021

AbstractBackgroundAntiviral therapy should reduce the recurrence of hepatitis B virus‐related hepatocellular carcinoma (HBV‐related HCC) after surgical resection. However, there is little research on whether various antiviral drugs have different prognostic effects in patients with HBV‐related HCC after curative liver resection. The present study compared the effects of nucleotide analog (NtA) and nucleoside analog (NsA) antiviral therapies after surgical resection on the prognosis of HBV‐related HCC.MethodsA total of 1303 patients with HBV‐related HCC who received curative hepatectomy at five institutes between April 2014 and April 2019 were retrospectively enrolled and analyzed. Propensity matching analysis was used to compare the outcomes of HCC patients given NsA versus NtA therapy. Subgroup analysis of patients treated with entecavir (ETV) and tenofovir disoproxil fumarate (TDF) was also performed.ResultsAmong 1303 patients, 759 (58.2%) patients developed recurrence, and 460 (35.3%) patients died. Multivariable analyses revealed that NtA therapy significantly decreased the risk of HCC recurrence (hazard ratio [HR], 0.64; 95% confidence interval [CI], 0.51–0.80; p < 0.001) and HCC‐related death (HR, 0.52; 95% CI, 0.36–0.76; p = 0.001) compared to that with NsA therapy. Subgroup analysis showed that TDF treatment was associated with significantly lower rates of HCC recurrence (HR, 0.64; 95% CI, 0.49–0.83; p = 0.001) and death (HR, 0.32; 95% CI, 0.20–0.50; p < 0.001) than ETV treatment.ConclusionsNucleotide analog treatment, but not NsA treatment, significantly reduced the risk of HCC recurrence in patients with HBV‐related HCC and improved overall survival after curative hepatic resection.
Central retinal artery occlusion in optic disk melanocytoma
Authors: Khadka Simanta , Byanju Raghunandan , Pradhan Sangita 
Published: October 2021

AbstractOptic disk melanocytoma (ODM) is a rare benign tumor of the optic disk. We report a rare occurrence of profound visual loss due to central retinal artery occlusion associated with ODM in a 78‐year‐old female with no significant medical history. The clinical findings were supplemented by ancillary investigations.
Prediction of Gas‐Phase Acidities of Strong Brønsted Acids by ONIOM Method
Authors: Fukaya Haruhiko , Ono Taizo , Sonoda Takaaki , Mishima Masaaki 
Published: October 2021

AbstractThe gas‐phase acidities of very strong neutral Brønsted acids are estimated based on Gaussian theory and two‐layer ONIOM calculations. Although the calculated gas‐phase acidities using Gaussian theory are in excellent agreement with the experimental values, these high‐level calculations are limited to small molecules because of their high computational cost. ONIOM calculation with the smallest model system, where only the acid center is placed in the high layer, gives relatively poor results. In contrast, ONIOM calculation with a model system expanded to neighbor atoms or the next neighbor atoms of the acid center gives estimates of gas‐phase acidities with practically useful accuracy.
ScaleReactor: A graceful performance isolation agent with interference detection and investigation for container‐based scale‐out workloads
Authors: Zhu Jianyong , Hu Chunming , Wo Tianyu , Yu Xiaoqiang 
Published: October 2021

SummaryStriking a balance between improved cluster utilization and guaranteed application QoS is a long‐standing research problem in multi‐tenants shared cluster. The typical solution is to detect performance degradation and investigate the root cause to conduct performance isolation. Existing efforts rely on lots of prior knowledge of applications and the assumption of interference‐free workload placement is possible. Performance interference is usually mitigated through application‐level approaches such as centralized rescheduling, which is usually an hindsight and a waste of resources. In this article, we present ScaleReactor, a graceful runtime agent on a per node basis that decouples the performance isolation from centralized resource management, and migrates the performance interference of scale‐out workloads in container‐based cluster using a lightweight black‐box approach. ScaleReactor analyzes the degree of contention for multi‐dimensional resources among co‐located workloads to detect the performance degradation without additional prior information, and uses correlation analysis to locate the cause of contention, while isolating resources in a graceful manner to reduce system overhead and the performance degradation of intrusive workloads. Experiments have demonstrated that ScaleReactor effectively reduces the job completion time of scale‐out applications in shared clusters, with the maximum value up to 36% and low system overhead against the existing isolation mechanism.
Sensitive detection of testosterone and testosterone prohormone administrations based on urinary concentrations and carbon isotope ratios of androsterone and etiocholanolone
Authors: Piper Thomas , Haenelt Nadine , Fusshöller Gregor , Geyer Hans , Thevis Mario 
Published: October 2021

AbstractThe testing strategy for the detection of testosterone (T) or T‐prohormones is based on the longitudinal evaluation of urinary steroid concentrations accompanied by subsequent isotope ratio mass spectrometry (IRMS)‐based confirmation of samples showing atypical concentrations or concentration ratios. In recent years, the IRMS methodology focussed more and more on T itself and on the metabolites of T, 5α‐ and 5β‐androstanediol. These target analytes showed the best sensitivity and retrospectivity, but their use has occasionally been challenging due to their comparably low urinary concentrations. Conversely, the carbon isotope ratios (CIR) of the main urinary metabolites of T, androsterone (A) and etiocholanolone (EITO), can readily be measured even from low urine volumes; those however, commonly offer a lower sensitivity and shorter retrospectivity in uncovering T misuse. Within this study, the CIRs of A and ETIO were combined with their urinary concentrations, resulting in a single parameter referred to as ‘difference from weighted mean’ (DWM). Both glucuronidated and sulfated steroids were investigated, encompassing a reference population (n = 110), longitudinal studies on three individuals, influence of ethanol in two individuals, and re‐analysis of several administration studies including T, dihydrotestosterone, androstenedione, epiandrosterone, dehydroepiandrosterone, and T‐gel. Especially DWM calculated for the sulfoconjugated steroids significantly prolonged the detection time of steroid hormone administrations when individual reference ranges were applied. Administration studies employing T encompassing CIR common for Europe (−23.8‰ and −24.4‰) were investigated and, even though for a significantly shorter time period and less pronounced, DWM could demonstrate the exogenous source of T metabolites.
Identification of chromatin states during zebrafish gastrulation using CUT&RUN and CUT&Tag
Authors: Akdogan‐Ozdilek Bagdeser , Duval Katherine L. , Meng Fanju W. , Murphy Patrick J. , Goll Mary G. 
Published: October 2021

AbstractBackgroundCell fate decisions are governed by interactions between sequence‐specific transcription factors and a dynamic chromatin landscape. Zebrafish offer a powerful system for probing the mechanisms that drive these cell fate choices, especially in the context of early embryogenesis. However, technical challenges associated with conventional methods for chromatin profiling have slowed progress toward understanding the exact relationships between chromatin changes, transcription factor binding, and cellular differentiation during zebrafish embryogenesis.ResultsTo overcome these challenges, we adapted the chromatin profiling methods Cleavage Under Targets and Release Using Nuclease (CUT&RUN) and CUT&Tag for use in zebrafish and applied these methods to generate high‐resolution enrichment maps for H3K4me3, H3K27me3, H3K9me3, RNA polymerase II, and the histone variant H2A.Z using tissue isolated from whole, mid‐gastrula stage embryos. Using this data, we identify a subset of genes that may be bivalently regulated during both zebrafish and mouse gastrulation, provide evidence for an evolving H2A.Z landscape during embryo development, and demonstrate the effectiveness of CUT&RUN for detecting H3K9me3 enrichment at repetitive sequences.ConclusionsOur results demonstrate the power of combining CUT&RUN and CUT&Tag methods with the strengths of the zebrafish system to define emerging chromatin landscapes in the context of vertebrate embryogenesis.
“Why don't behavior analysts do something?”1 Behavior analysts' historical, present, and potential future actions on sexual and gender minority issues
Authors: Capriotti Matthew R. , Donaldson Jeanne M. 
Published: October 2021

For thousands of years, societies actively practiced the oppression, persecution, and dehumanization of sexual and gender minority (SGM) people (e.g., lesbian, gay, bisexual, transgender, and queer individuals). Rekers and Lovaas' (1974) study is part of that history within behavior analysis. Following requests for retraction, the Society for the Experimental Analysis of Behavior and LeBlanc (2020) issued a formal Expression of Concern about the work. Continued conversation and debate have followed. First, we contextualize debate around retraction of Rekers and Lovaas and the history of behavior analysts' work on SGM issues. Second, we propose 5 steps that leaders in behavior analysis can take with relative immediacy, and we describe 5 research areas that individual behavior analysts could pursue. We conclude that behavior analysts can contribute much toward the liberation of SGM individuals if we begin to bring our science to bear on pressing, socially significant issues facing SGM communities.
Reporting of Cochrane systematic review protocols with network meta‐analyses—A scoping review
Authors: Wang Rui , Dwan Kerry , Showell Marian G. , van Wely Madelon , Mol Ben W. , Askie Lisa , Seidler Anna Lene 
Published: October 2021

AbstractPublishing systematic review protocols is a fundamental part of systematic reviews to ensure transparency and reproducibility. In this scoping review, we aimed to evaluate reporting of Cochrane systematic review protocols with network meta‐analyses (NMA). We searched all Cochrane NMA protocols published in 2018 and 2019, and assessed the characteristics and reporting of methodologies relevant to NMA. We reported frequencies for each reporting item. Forty‐five protocols were assessed, including two for overviews and 43 for intervention reviews. Thirty‐three (73%) were labelled as NMA protocols in the title. Forty‐two (95%) justified the need of an NMA and 40 (89%) used appropriate search strategies to identify potential eligible studies. About half (24, 53%) considered the transitivity assumption when reporting inclusion criteria and 35 (78%) specified potential effect modifiers. Forty‐three (96%) reported statistical software for NMA, 25 (56%) reported NMA model choice, 32 (71%) reported framework choice and 32 (71%) reported assumption about heterogeneity variances. Protocols varied in whether they reported methods for relative ranking (35, 78%), statistical inconsistency (40, 89%), reporting bias (44, 98%) and sources of heterogeneity (39, 87%). In conclusion, Cochrane NMA protocols reported multiple NMA‐specific items well, but could be further improved, especially regarding transitivity assumptions. Our recommendations for NMA protocol reporting based on this scoping review could assist authors, reviewers, and editors to improve NMA protocols.
Absorption to and emission from the excited electronic state 11Bu in long linear all‐trans‐polyenes: The case of ttbP9 and ttbP11
Authors: Catalán Javier , Hopf Henning , Klein Dagmar , Kilickiran Pinar 
Published: October 2021

AbstractA 1:1‐mixture of decalin and methylcyclohexane (v/v), generates a solvent mixture that allows measurements at temperatures as low as 77 K of the emission and absorption spectra of long‐chain linear polyenes. This solvent mixture, on lowering the temperature also generates interesting increases in polarizability and viscosity that undoubtedly facilitate the study of these important compounds. In this study, we show that the two polyenes studied, ttbP9 and ttbP11, generate photophysical behavior that can be explained by the presence of their excited 11Bu state, as the first excited electronic state. Consequently, the solvatochromism of the absorption and the emission of these two polyenes are equally sensitive to the polarizability of the solvent used. We must also point out that the absorption and emission spectra of ttbP9 and ttbP11, whose molecular structures have a long polyene chain, do not show Stokes shift. This is especially relevant when it is commonly accepted that polyene compounds have a Stokes shift that increases with the length of their polyene chain.