bluuebunny/crossref_metadata_2025_split huggingface dataset:
How to Identify Exoplanet Surfaces Using Atmospheric Trace Species in Hydrogen-dominated Atmospheres
Authors: Yu 余馨 Xinting 婷 , Moses Julianne I. , Fortney Jonathan J. , Zhang Xi 
Published: June 2021

Abstract
Sub-Neptunes (R

p
∼ 1.25–4 R
Earth) remain the most commonly detected exoplanets to date. However, it remains difficult for observations to tell whether these intermediate-sized exoplanets have surfaces and where their surfaces are located. Here we propose that the abundances of trace species in the visible atmospheres of these sub-Neptunes can be used as proxies for determining the existence of surfaces and approximate surface conditions. As an example, we used a state-of-the-art photochemical model to simulate the atmospheric evolution of K2-18b and investigate its final steady-state composition with surfaces located at different pressures levels (P
surf). We find that the surface location has a significant impact on the atmospheric abundances of trace species, making them deviate significantly from their thermochemical equilibrium and “no-surface” conditions. This result arises primarily because the pressure–temperature conditions at the surface determine whether photochemically produced species can be recycled back to their favored thermochemical equilibrium forms and transported back to the upper atmosphere. For an assumed H2-rich atmosphere for K2-18b, we identify seven chemical species that are most sensitive to the existence of surfaces: ammonia (NH3), methane (CH4), hydrogen cyanide (HCN), acetylene (C2H2), ethane (C2H6), carbon monoxide (CO), and carbon dioxide (CO2). The ratio between the observed and the no-surface abundances of these species can help distinguish the existence of a shallow surface (P
surf < 10 bar), an intermediate surface (10 bar < P
surf < 100 bar), and a deep surface (P
surf > 100 bar). This framework can be applied together with future observations to other sub-Neptunes of interest.
Involvement of Activation of Mast Cells via IgE Signaling and Epithelial Cell–Derived Cytokines in the Pathogenesis of Pollen Food Allergy Syndrome in a Murine Model
Authors: Kato Yukinori , Morikawa Taiyo , Kato Eiichi , Yoshida Kanako , Imoto Yoshimasa , Sakashita Masafumi , Osawa Yoko , Takabayashi Tetsuji , Kubo Masato , Miura Kenji , Noguchi Emiko , Fujieda Shigeharu 
Published: June 2021

Abstract
Murine models to elucidate the pathogenesis of pollen food allergy syndrome (PFAS), characterized by oral hypersensitivity symptoms induced by specific foods in patients previously sensitized with a pollen, are lacking. The study aimed to examine PFAS pathogenesis in a novel murine model. Birch pollen–immunized mice were orally administered apple extract, and oral symptoms were evaluated based on oral rubbing frequency following the challenge. The birch pollen–immunized mice orally challenged with apple extract exhibited PFAS-like symptoms, including oral rubbing and positive reaction of swelling by the prick test. The apple extract administered with a protease inhibitor reduced the oral rubbing frequency, which was also significantly reduced in the immunized Fcer1a−/− and mast cell–deficient mice compared with the immunized control mice. The oral rubbing frequency, serum IgE levels, and Th2-cytokine production by the cervical lymph node cells were significantly reduced in the immunized Il-33−/− and thymic stromal lymphopoietin receptor–deficient (Crlf2−/−) mice as compared with the immunized wild-type mice. IL-33 and thymic stromal lymphopoietin involve the pathogenesis of PFAS. The apple-extract stimulation did not lead to increased Th2-cytokine production in the oral mucosa or number of group 2 innate lymphoid cells or eosinophils. PFAS involves an early-phase response by mast cell degranulation via IgE signaling after the cross-reactivity of Bet v 1–specific IgE and the food allergen, and exacerbation of allergic symptom via proteases in food; PFAS does not involve a late phase with local Th2/eosinophilic inflammation in the oral mucosa. This novel murine model might be used for elucidating the pathogenesis and assessing new therapeutic strategies for PFAS.
Clinical and Radiographic Analysis of Novabone Putty with Platelet-Rich Fibrin in the Treatment of Periodontal Intrabony Defects
Authors: Hazari Vibhor , Choudhary Anushree , Mishra Rohit , Chandrashekar Kabbur Thipanna , Trivedi Ashima , Pathak Pranshu Kumar 
Published: June 2021

Background:
Periodontal regeneration remains one of the crucial issues in the field of periodontology. Periodontal intrabony defects could be treated by surgical intervention through various alloplastic bone graft substitutes. The Food and Drug Administration approved, Novabone putty is one of the recently marketed bone graft substitutes, which has been used in the present study. This study also incorporates the placement of platelet-rich fibrin (PRF) in combination with Novabone putty.

Materials and Methods:
Twenty patients were included in the study and were allocated to either Group A or Group B through randomization. Group A included the placement of Novabone putty in the periodontal intrabony defects, whereas Group B included the placement of Novabone putty along with PRF. Statistical analysis of plaque index, gingival index, probing pocket depth, relative attachment level, and intraoral periapical radiographs was performed.

Results:
Statistical more significant difference (P < 0.05) in probing pocket depth, and relative attachment level was observed in Group B (Novabone putty and PRF) in comparison to Group A (Novabone putty).

Conclusion:
Evaluation of efficacy of Novabone putty along with PRF produced more favorable results in relative attachment level gain and more reduction in probing pocket depth when compared to Novabone putty alone.
Allogeneic Bone Application in Association with Platelet-Rich Plasma for Alveolar Bone Grafting of Cleft Palate Defects
Authors: Ferreira Cimara Fortes , Carlini João Luiz , Magini Ricardo de Souza , Gil José Nazareno , Zétola André Luis 
Published: June 2021

Aim:
The aim of this study is to compare allogeneic bone grafts associated with platelet-rich plasma (ALBGs-PRP) to autogenous bone grafts (ATBGs) for alveolar reconstructions in patients with cleft lip and palate (CLP).

Materials and Methods:
The Maxillofacial Surgery Service of the Comprehensive Care Center for CLP (CCCLP) in Curitiba (Paraná, Brazil).

Patients:
Thirty out of 46 patients with 8–12 years of age and pre- or trans-foramen unilateral clefts were operated by the same surgeon. Groups were selected randomly after coin-toss for the first surgery to be ALBG-PRP.

Interventions:
Pre- and post-surgery cleft defect severity was registered by a score system using superimposed digitalized peri-apical radiographs. The hypothesis indicated ABG-PRP to be similar to the ABG was proved.

Results:
There was no statistically significant difference (P < 0.05) in bone augmentation for the ABG-PRP group (79.88%) when compared to the ABG group (79.9%).

Conclusion:
ABG-PRP is indicated as a successful treatment modality to reduce the need for additional donor sites and reduce morbidity and hospital stay.
Long-Lasting Insecticidal Nets Incorporating Piperonyl Butoxide Reduce the Risk of Malaria in Children in Western Kenya: A Cluster Randomized Controlled Trial
Authors: Minakawa Noboru , Kongere James O. , Sonye George O. , Lutiali Peter A. , Awuor Beatrice , Kawada Hitoshi , Isozumi Rie , Futami Kyoko 
Published: June 2021

ABSTRACT.
Malaria vectors have acquired an enzyme that metabolizes pyrethroids. To tackle this problem, we evaluated long-lasting insecticidal nets incorporating piperonyl butoxide (PBO-LLINs) with a community-based cluster randomized control trial in western Kenya. The primary endpoints were anopheline density and Plasmodium falciparum polymerase chain reaction (PCR)-positive prevalence (PCRpfPR) of children aged 7 months to 10 years. Four clusters were randomly selected for each of the treatment and control arms (eight clusters in total) from 12 clusters, and PBO-LLINs and standard LLINs were distributed in February 2011 to 982 and 1,028 houses for treatment and control arms, respectively. Entomological surveys targeted 20 houses in each cluster, and epidemiological surveys targeted 150 children. Cluster-level permutation tests evaluated the effectiveness using the fitted values from individual level regression models adjusted for baseline. Bootstrapping estimated 95% confidence intervals (CIs). The medians of anophelines per house were 1.4 (interquartile range [IQR]: 2.3) and 3.4 (IQR: 3.7) in the intervention and control arms after 3 months, and 0.4 (IQR: 0.2) and 1.6 (IQR: 0.5) after 10 months, respectively. The differences were –2.5 (95% CI: –6.4 to –0.6) and –1.3 (95% CI: –2.0 to –0.7), respectively. The datasets of 861 and 775 children were analyzed in two epidemiological surveys. The median PCRpfPRs were 25% (IQR: 11%) in the intervention arm and 52% (IQR: 11%) in the control arm after 5 months and 33% (IQR: 11%) and 45% (IQR: 5%) after 12 months. The PCRpfPR ratios were 0.67 (95% CI: 0.38, 0.91) and 0.74 (95% CI: 0.53, 0.90), respectively. We confirmed the superiority of PBO-LLINs.
Systems-Level Reforms to the US Resident Selection Process: A Scoping Review
Authors: Zastrow Ryley K. , Burk-Rafel Jesse , London Daniel A. 
Published: June 2021

ABSTRACT

Background
Calls to reform the US resident selection process are growing, given increasing competition and inefficiencies of the current system. Though numerous reforms have been proposed, they have not been comprehensively cataloged.

Objective
This scoping review was conducted to characterize and categorize literature proposing systems-level reforms to the resident selection process.

Methods
Following Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines, searches of Embase, MEDLINE, Scopus, and Web of Science databases were performed for references published from January 2005 to February 2020. Articles were included if they proposed reforms that were applicable or generalizable to all applicants, medical schools, or residency programs. An inductive approach to qualitative content analysis was used to generate codes and higher-order categories.

Results
Of 10 407 unique references screened, 116 met our inclusion criteria. Qualitative analysis generated 34 codes that were grouped into 14 categories according to the broad stages of resident selection: application submission, application review, interviews, and the Match. The most commonly proposed reforms were implementation of an application cap (n = 28), creation of a standardized program database (n = 21), utilization of standardized letters of evaluation (n = 20), and pre-interview screening (n = 13).

Conclusions
This scoping review collated and categorized proposed reforms to the resident selection process, developing a common language and framework to facilitate national conversations and change.
THE PUN-GROUP OF LINGUISTIC DEVICES IN ADVERTISING MEDIA DISCOURSE
Authors: Arakelyan Hamlet 
Published: June 2021

The language of advertising is unique and very peculiar in comparison with other elements of media discourse. The effectiveness of speech in advertising media discourse focuses on catching the attention of the target audience. Since the language of advertising is characterized by a distinguished persuasive function, the creators of ads spare no effort to make them catchy, interesting and witty. This is the reason why various linguistic devices are used to facilitate the comprehension and memorization of advertisements. In this regard, wordplay plays a significant role as the intentional usage of puns ensures the effectiveness of the composed texts.
Potential of Actinomycetes Isolates as Antimicrobials for Salmonella typhi
Authors: Hilwah Hilwah , Bahar Meiskha , Pramono Andri Pramesyanti 
Published: June 2021

Actinomycetes are aerobic bacteria and Gram-positive bacilli. Acinomycets have an antimicrobial, antitumor, immunosuppressive, and antiparasitic acivity. This study aims to determine the antimicrobial potency of Actinomycetes against Salmonella typhi. The research design was a true experimental design with Actinomycetes isolates obtained from the Microbiology Laboratory of the Veteran National Development University, Jakarta. Rejuvenation of Actinomycetes isolates used spread plate method on media Starch Casein Agar (SCA) with six serial dilutions of 10-1, 10-2, 10-3, 10-4, 10-5, and 10-6. The antimicrobial test method used the liquid dilution method to determine the value of the minimum inhibitory concentration (MIC) with Trypticase Soy Broth (TSB) media followed by colony calculations on Salmonella Shigella Agar (SSA) media to determine the value of the minimum bactericidal concentration (MBC). The results showed that the antimicrobial activity of Actinomycetes isolates is bacteriostatic with MIC value of 10-2. MBC value cannot be determined. It can be concluded that there is a potential of Actinomycetes isolates as an antimicrobial against Salmonella typhi (p <0.05).
TELERREABILITAÇÃO E TELEMONITORAMENTO CARDIORRESPIRATÓRIO EM TEMPOS DE PANDEMIA DE COVID-19
Authors: Freitas Camila Machado de Freitas , Alves Camila Martins Alves , Aparecida Correa Feltrin Luciana , Oliveira Adriana Paulino de , Maia Laura Cristiana Pereira Maia 
Published: June 2021

Introdução: A COVID-19 tem representado um desafio global aos sistemas de saúde, expandindo em velocidade crescente de óbitos. Métodos para controlar a propagação da doença como o isolamento social e o rastreio dos contactantes dos casos têm sido utilizados no mundo. Com o surgimento da COVID-19 foi necessário a expansão das aplicações e adoção de tecnologias de Telessaúde. Objetivo: Descrever os efeitos da telerreabilitação e do telemonitoramento cardiorrespiratório nos pacientes DPOC em isolamento social. Método: Pesquisa transversal, prospectiva. Foram avaliados 8 pacientes com diagnóstico de DPOC. Foram realizados 10 encontros através de plataforma digitais. Para avaliação foram aplicados os questionários de Medida de Independência Funcional, SF-36, Airways questionnaire 20 e Inventário de Depressão de Beck II, inicial e ao final do protocolo. Resultados: Houve resultados positivos, tendo visto que o telemonitoramento e a telerreabilitação foram uma alternativa para esses pacientes manterem o tratamento. E assim o protocolo de reabilitação manteve a funcionalidade dos indivíduos, quanto à melhora de sintomas de ansiedade 25% dos pacientes tinham sintomas de depressão e após o programa de reabilitação somente 12,5% apresentou sintomas. O grau obstrutivo de vias áreas 37,5% dos participantes apresentaram grau de acometimento leve e após o programa 50%. De forma que houve aumento da pontuação da qualidade de vida dos mesmos. Conclusão: Verificamos que o telemonitoramento e telerreabilitação podem auxiliar na continuidade do programa de reabilitação fisioterapêutica dos pacientes com DPOC, superando as dificuldades de funcionalidade, obstrução de vias aéreas e depressão, melhorando assim a qualidade de vida.
PROTAGONISMOS LEIGOS ALTERNATIVOS NAS TRAJETÓRIAS DE SAÚDE: DA MEDICALIZAÇÃO À ‘NATURALIZAÇÃO’ DA VIDA.
Authors: Rosa Maria do Rosário Tomás , Alves Maria de Fátima Pereira 
Published: June 2021

Este artigo pretende refletir sobre as propriedades heurísticas dos ‘protagonismos leigos alternativos’ nas trajetórias de saúde para a compreensão da resistência ou reforço da medicalização da vida, através da procura do ‘natural’ observada nos discursos dos utilizadores de medicinas alternativas e complementares (MAC), recolhidos através de entrevistas semiestruturadas[1]. Os ‘protagonismos leigos alternativos’ refletem processos subjacentes à construção de trajetórias individuais de relação com a saúde, onde são mobilizadas abordagens alternativas, complementares ou não-convencionais que se diferenciam das do sistema biomédico. Para isso estabelecemos um diálogo teórico que parte da racionalidade biomédica dominante, para o questionamento dos sentidos e significados da agência leiga que integra o recurso às MAC nas suas trajetórias de saúde. O enfoque da nossa reflexão centra-se na compreensão das lógicas da ação leiga presentes na construção das trajetórias de saúde. São estes sentidos e lógicas que abordamos neste artigo, debatendo de que modo a procura de uma saúde e de um ‘saudável’ associados à natureza e ao ‘natural’ constituem uma resistência ou um reforço da medicalização da vida.

[1] A pesquisa foi efetuada no âmbito de tese de doutoramento de Rosa, R. (2013). Protagonismos leigos alternativos nas trajetórias de saúde. Tese de doutoramento. Universidade Aberta. Lisboa. Apoio da FCT-BD: SFRH/BD/30210/2006
Khảo sát sự hài lòng của các bà mẹ có con đến khám Tại phòng tái khám và các bà mẹ có con nằm điều trị nội trú tại khoa nhi bệnh viện trường đại học y dược huế
Authors: Tram Duong Thi Quynh , Thanh Nguyen Thi Minh 
Published: June 2021

Đặt vấn đề và mục tiêu:Cải tiến chất lượng khám chữa bệnh (KCB) tuân thủ nguyên tắc tổ chức, thực hiện quản lý chất lượng là lấy người bệnh (NB) làm trung tâm, là nhiệm vụ trọng tâm, xuyên suốt của BV. Tất cả nhân viên y tế (NVYT) trong BV có trách nhiệm tham gia hoạt động quản lý chất lượng nhằm đổi mới và hoàn thiện hệ thống y tế theo hướng công bằng, hiệu quả và phát triển, tạo cơ hội thuận lợi cho mọi người dân được bảo vệ, chăm sóc và nâng cao sức khoẻ với chất lượng ngày càng cao. Hơn nữa, chăm sóc sức khỏe trẻ em là nhiệm vụ hết sức quan trọng của toàn bộ xã hội. Vì vậy, nghiên cứu này thực hiện với mục tiêu: Đánh giá mức độ hài lòng của các bà mẹ đưa con đến khám tại phòng tái khám và các bà mẹ có con nằm điều trị nội trú và các yếu tố liên quan tại khoa nhi Bệnh viện Trường Đại học Y Dược Huế.
Phương pháp: Nghiên cứu được tiến hành trên 72 bà mẹ có con đến khám tại phòng tái khám và 72 bà mẹ có con nằm điều trị nội trú tại khoa Nhi, Bệnh viện Trường Đại học Y Dược Huế trong thời gian tháng 2 năm 2020 đến tháng 10 năm 2020. Phương pháp nghiên cứu mô tả cắt ngang. Thu thập số bằng phát vấn bộ công cụ khảo sát, đánh giá lại mức độ tin cậy của hai bộ câu hỏi với chỉ số Cronbach alpha lần lượt là 0,93 và 0,94. Phân tích bằng phần mềm SPSS 20.
Kết quả: Các bà mẹ đưa con đến khám tại phòng tái khám và các bà mẹ có con nằm điều trị nội trú tại khoa Nhi, Bệnh viện Trường Đại học Y Dược Huế có mức độ hài lòng cao về “Khả năng tiếp cận” với tất cả các biển báo, chỉ dẫn, hướng dẫn; về “sự minh bạch thông tin và thủ tục khám bệnh, điều trị”; “Cơ sở vật chất và phương tiện phục vụ người bệnh”; “thái độ ứng xử, năng lực chuyên môn của nhân viên y tế”; “kết quả cung cấp dịch vụ” của bệnh viện; có mối liên quan giữa tôn giáo và sự hài lòng của bà mẹ về kết quả cung cấp dịch vụ (với p<0,05) và có mối liên quan giữa tình trạng hôn nhân và sự hài lòng của bà mẹ về cơ sở vật chất và phương tiện phục vụ người bệnh (với p<0,05); có mối liên quan giữa trình độ học vấn và sự hài lòng của bà mẹ về khả năng tiếp cận (với p<0,05) và có mối liên quan giữa trình độ học vấn và sự hài lòng của bà mẹ về sự minh bạch thông tin và thủ tục khám bệnh, điều trị (với p<0,05).
Kết luận: Sự hài lòng của người bệnh và người nhà bệnh nhân là một trong những chỉ số rất quan trọng để đánh giá chất lượng của bệnh viện. Chính vì vậy, mỗi bệnh viện nên có kế hoạch nâng cao mức độ của bệnh nhân và người nhà bệnh nhân để tạo lên giá trị cao hơn của bệnh viện.
Comparison between traditional resistance exercise and variable resistance with elastic bands in acute vertical jump performance
Authors: Popp Marin Douglas , Anthony Astorino Todd , Silva Serafim Allan Igor , Bertoldo Urtado Christiano , Prestes Jonato , Tubagi Polito Luis Felipe , Otton Rosemari 
Published: June 2021

PurposeResistance exercise (RE) with variable resistance (VR) may be an interesting strategy to increase strength and power in several sports activities. The present study aimed to compare the effect of RE vs. VR exercise in the back squat on subsequent jump performance at different time points.MethodsNine male elite handball athletes (age: 21.4 ± 2.1 years; body fat percentage: 10.5 ± 4.2%) undergoing in-season training participated in the study. They randomly completed 3 sets of 5 back squat repetitions at 85% of predicted one-repetition maximum (1RM) with 3-minute rests between sets. They performed RE back squat alone or VR back squat by combining 55% of 1RM using standard weight plates and 29.7 ± 2.0% of the athlete’s 1RM in fully erect position (starting position) with elastic band resistance. Countermovement jump (CMJ) test was applied at baseline, immediately after the conditioning activity (within 15 seconds), and every 2 minutes after the protocols (2, 4, 6, and 8 minutes).ResultsThere was a very large (5.8%, <i>p</i> = 0.02, <i>ES</i> = 1.53) increase in CMJ performance 2 minutes after VR back squat, while no significant changes were observed after the completion of RE back squat. Moreover, there was a large (<i>p</i> = 0.04, <i>ES</i> = 1.27) increase in peak power after VR exercise.ConclusionsCMJ performance and peak power output can be potentiated after 2 minutes of recovery following the completion of back squat exercise combining RE plus elastic bands, reinforcing the practical applicability of VR exercise.
No rastro historiográfico da Psicanálise no Brasil
Authors: Librelotto Rubin Aline 
Published: June 2021

Neste trabalho elaboramos uma articulação entre as diferentes tradições e momentos dos estudos historiográficos da Psicanálise no Brasil, desde sua emergência na década de 1920. Buscamos situar historicamente continuidades e descontinuidades promulgadas pela virada epistemológica dos anos 1970. Com vistas a uma critica a abordagem historiográfica que se construiu dentro do paradigma da “ficção científica” e da “verdadeira psicanálise”, propomos um retorno à “ficção teórica” de Freud, como definido pelo historiador Michel De Certeau. Além disso, visando a construção de uma historiografia psicanalítica que se baseie em preceitos aliados a sua própria teoria, convocamos alguns elementos da teoria do texto de Barthes, como a escritura baseada no desejo e não na autoria.
Palavras-chaves: Historiografia psicanalítica; verdadeira psicanálise; ficção teórica.
The Obscure Object of Rhetoric
Authors: Wagner Nathan R. 
Published: June 2021

ABSTRACT
This paper proposes a vision of rhetoric as metaphysical enactment. This position contrasts with traditionally accepted views of rhetoric as phenomenological practice, evidenced prominently in contemporary rhetorical theory. I advance a framework that employs metaphorical accommodation and indicates a way that rhetoric can be situated as a perpetually productive force. The analytic tradition affords a method and vocabulary that when placed in conversation with rhetorical studies offers an alternative for viewing rhetoric as metaphysical enactment. I determine that rhetorical theory should engage with rhetoric as a measure of action, activity, and vitality that raises our awareness and connects us.