bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence, Co-morbidities and Management of Psoriasis in Saudi Arabia: A Review
Authors: Alenazy Afaf Enad , Alenazy Asmaa Enad S. , Alanazi Maali Salamah N. , Alshammari Manal Nashi 
Published: September 2021

Background: Psoriasis is a chronic inflammatory skin illness with an autoimmune pathogenic mannerisms and genetic tendency. It is regarded as erythematous plaques sheltered with silvery scales predominantly over the extensor exteriors, scalp, and lumbosacral region. The prevalence in Saudi Arabia was projected to be 5.3% (53% of psoriasis patients develop it before 30 years of age.
Aim: The main objective of this study is to summarize the current evidence regarding prevalence, types, risk factors, associated comorbidities and management of psoriasis in Saudi Arabia.
Methods: This is a systematic review was carried out, including PubMed, Google Scholar, and EBSCO that examining previous studies regarding psoriasis in KSA. Authors extracted the data, and then the author's names, year and region of publication, the study type, period of study, and the result were reported.
Results: The review included 7 studies that illustrate prevalence, types, risk factors, associated comorbidities and management of psoriasis in Saudi Arabia.
Conclusion: The incidence of psoriasis in Saudi Arabia is within previously reported figures worldwide. Family history seems to have a strong association with the occurrence of psoriasis. CVD and psychological disorders seem to be prevalent Saudi psoriatic patients. Topical medications are widely used and effective in psoriasis management in Saudi Arabia.
Construction of a calendar for people with hypertension for self-care in the hospital - home transition / Construção de calendário à pessoa com hipertensão para o cuidado/ autocuidado na transição hospital – domicílio
Authors: Fava Silvana Maria Coelho Leite , Silveira Letícia Kühn , Carvalho-Peloso Bianca de Moura , Dázio Eliza Maria Rezende , Freitas Patrícia Scotini , Morais Camila Mendonça de 
Published: September 2021

Objetivo: descrever a construção de um material educativo em forma de calendário para o autocuidado às pessoas com hipertensão arterial no processo de transição hospital-domicílio. Método: estudo metodológico fundamentado em critérios para a elaboração de materiais educativos, na revisão de escopo, nos princípios da literacia em saúde e da Andragogia. Resultados: construção do calendário ilustrado, com os temas: definições da hipertensão arterial; valores da pressão arterial; técnica para a medida da pressão arterial; estratégias para o controle da pressão arterial; tratamento não farmacológico e farmacológico da hipertensão e direitos da pessoa com Hipertensão arterial. Conclusão: a construção do material educativo no formato de calendário às pessoas com hipertensão arterial no processo de transição hospital- domicílio pode contribuir para a continuidade dos cuidados, com potencial para a pessoa cuidar melhor de si.
Construction of Polyoxometalate‐Based Material for Eliminating Multiple Pb‐Based Defects and Enhancing Thermal Stability of Perovskite Solar Cells
Authors: Wang Wei , Zhang Jian , Lin Kaifeng , Dong Yayu , Wang Jiaqi , Hu Boyuan , Li Jiao , Shi Zhe , Hu Yanjing , Cao Wei , Xia Debin , Fan Ruiqing , Yang Yulin 
Published: September 2021

AbstractThe high‐quality perovskite film with few defects plays an important role in the power conversion efficiency (PCE) and long‐term stability of perovskite solar cells. Here, an efficient strategy is proposed to eliminate Pb0 and passivate Pb2+ simultaneously by employing a stable polyoxometalate‐based material CoW12@MIL‐101(Cr) in the precursor solution of perovskite. The controllable oxidation ability of CoW12 is optimized through the interaction with metal–organic frameworks, resulting in a doped perovskite film with regular morphology, large grain size, and low defects density. The solvent effects and formation of intermediate materials in the precursor solution are further investigated by an in situ thermogravimetry‐Fourier transform infrared spectroscopy analysis. In addition, the champion doped‐device showed enhanced PCE to 21.39% and excellent stability, maintaining 85% and 89% of the original PCE after heating at 85 °C in N2 atmosphere and stored in ambient conditions (25 °C, 40% humidity) for 1000 h, respectively.
Kitkaite NiTeSe, an Ambient‐Stable Layered Dirac Semimetal with Low‐Energy Type‐II Fermions with Application Capabilities in Spintronics and Optoelectronics
Authors: Vobornik Ivana , Sarkar Anan Bari , Zhang Libo , Boukhvalov Danil W. , Ghosh Barun , Piliai Lesia , Kuo Chia‐Nung , Mondal Debashis , Fujii Jun , Lue Chin Shan , Vorokhta Mykhailo , Xing Huaizhong , Wang Lin , Agarwal Amit , Politano Antonio 
Published: September 2021

AbstractThe emergence of Dirac semimetals has stimulated growing attention, owing to the considerable technological potential arising from their peculiar exotic quantum transport related to their nontrivial topological states. Especially, materials showing type‐II Dirac fermions afford novel device functionalities enabled by anisotropic optical and magnetotransport properties. Nevertheless, real technological implementation has remained elusive so far. Definitely, in most Dirac semimetals, the Dirac point lies deep below the Fermi level, limiting technological exploitation. Here, it is shown that kitkaite (NiTeSe) represents an ideal platform for type‐II Dirac fermiology based on spin‐resolved angle‐resolved photoemission spectroscopy and density functional theory. Precisely, the existence of type‐II bulk Dirac fermions is discovered in NiTeSe around the Fermi level and the presence of topological surface states with strong (≈50%) spin polarization. By means of surface‐science experiments in near‐ambient pressure conditions, chemical inertness towards ambient gases (oxygen and water) is also demonstrated. Correspondingly, NiTeSe‐based devices without encapsulation afford long‐term efficiency, as demonstrated by the direct implementation of a NiTeSe‐based microwave receiver with a room‐temperature photocurrent of 2.8 µA at 28 GHz and more than two orders of magnitude linear dynamic range. The findings are essential to bringing to fruition type‐II Dirac fermions in photonics, spintronics, and optoelectronics.
Small Intestinal Submucosa Membrane Modified by Fusion Peptide‐Mediated Extracellular Vesicles to Promote Tissue Regeneration
Authors: Zhang Lei , Ma Shiqing , Wei Pengfei , Zhao Yifan , Mu Yuzhu , Wu Jinzhe , Jing Wei , Zhao Bo , Deng Jiayin , Liu Zihao 
Published: September 2021

AbstractTissue injury, which often occurs in daily life, remains challenging in clinical medicine. Developing a novel biomaterial with the capability to provide an ideal microenvironment and homeostasis around the wound is highly desirable for effective tissue regenerative medicine. The small intestinal submucosa (SIS) membrane possesses a precise spatial structure with excellent biocompatibility. Extracellular vesicles (EVs) derived from umbilical cord mesenchymal stem cells can achieve rapid cell proliferation and migration with little immune response by creating a satisfactory microenvironment. In this study, fusion peptide‐mediated EVs are able to modify the surface of the SIS membrane via specific combination. In vitro studies prove that modified SIS membranes can promote cell migration and spreading. This phenomenon may be because of the activation of TEADs, which regulate cell behavior. By constructing a rat abdominal wall defect model, it is further demonstrated that the modified SIS membrane is more conducive to tissue regeneration. Collectively, these results suggest that SIS membranes modified by fusion peptide‐mediated EVs achieve excellent biofunction and provide promising prospects for tissue regeneration.
Molecule‐Upgraded van der Waals Contacts for Schottky‐Barrier‐Free Electronics
Authors: Zhang Xiankun , Kang Zhuo , Gao Li , Liu Baishan , Yu Huihui , Liao Qingliang , Zhang Zheng , Zhang Yue 
Published: September 2021

AbstractThe applications of any ultrathin semiconductor device are inseparable from high‐quality metal–semiconductor contacts with designed Schottky barriers. Building van der Waals (vdWs) contacts of 2D semiconductors represents an advanced strategy of lowering the Schottky barrier height by reducing interface states, but will finally fail at the theoretical minimum barrier due to the inevitable energy difference between the semiconductor electron affinity and the metal work function. Here, an effective molecule optimization strategy is reported to upgrade the general vdWs contacts, achieving near‐zero Schottky barriers and creating high‐performance electronic devices. The molecule treatment can induce the defect healing effect in p‐type semiconductors and further enhance the hole density, leading to an effectively thinned Schottky barrier width and improved carrier interface transmission efficiency. With an ultrathin Schottky barrier width of ≈2.17 nm and outstanding contact resistance of ≈9 kΩ µm in the optimized Au/WSe2 contacts, an ultrahigh field‐effect mobility of ≈148 cm2 V−1 s−1 in chemical vapor deposition grown WSe2 flakes is achieved. Unlike conventional chemical treatments, this molecule upgradation strategy leaves no residue and displays a high‐temperature stability at >200 °C. Furthermore, the Schottky barrier optimization is generalized to other metal–semiconductor contacts, including 1T‐PtSe2/WSe2, 1T′‐MoTe2/WSe2, 2H‐NbS2/WSe2, and Au/PdSe2, defining a simple, universal, and scalable method to minimize contact resistance.
Design Principles of Sodium/Potassium Protection Layer for High‐Power High‐Energy Sodium/Potassium‐Metal Batteries in Carbonate Electrolytes: a Case Study of Na2Te/K2Te
Authors: Yang Hai , He Fuxiang , Li Menghao , Huang Fanyang , Chen Zhihao , Shi Pengcheng , Liu Fanfan , Jiang Yu , He Lixin , Gu Meng , Yu Yan 
Published: September 2021

AbstractThe sodium (potassium)‐metal anodes combine low‐cost, high theoretical capacity, and high energy density, demonstrating promising application in sodium (potassium)‐metal batteries. However, the dendrites’ growth on the surface of Na (K) has impeded their practical application. Herein, density functional theory (DFT) results predict Na2Te/K2Te is beneficial for Na+/K+ transport and can effectively suppress the formation of the dendrites because of low Na+/K+ migration energy barrier and ultrahigh Na+/K+ diffusion coefficient of 3.7 × 10−10 cm2 s−1/1.6 × 10−10 cm2 s−1 (300 K), respectively. Then a Na2Te protection layer is prepared by directly painting the nanosized Te powder onto the sodium‐metal surface. The Na@Na2Te anode can last for 700 h in low‐cost carbonate electrolytes (1 mA cm−2, 1 mAh cm−2), and the corresponding Na3V2 (PO4)3//Na@Na2Te full cell exhibits high energy density of 223 Wh kg−1 at an unprecedented power density of 29687 W kg−1 as well as an ultrahigh capacity retention of 93% after 3000 cycles at 20 C. Besides, the K@K2Te‐based potassium‐metal full battery also demonstrates high power density of 20 577 W kg−1 with energy density of 154 Wh kg−1. This work opens up a new and promising avenue to stabilize sodium (potassium)‐metal anodes with simple and low‐cost interfacial layers.
Direct Atomic‐Scale Structure and Electric Field Imaging of Triazine‐Based Crystalline Carbon Nitride
Authors: Wang Wu , Cui Juan , Sun Zongzhao , Xie Lin , Mu Xiaoke , Huang Limin , He Jiaqing 
Published: September 2021

AbstractCrystalline carbon nitrides (CNs) have recently attracted considerable attention owing to their superior photocatalytic activity. However, the electron‐beam‐sensitive nature of crystalline CNs hinders atomic‐resolution imaging of their local structures by conventional (scanning) transmission electron microscopy ((S)TEM) techniques. Here, the atomic structure of a triazine‐based crystalline CN, poly(triazine imide) (PTI) incorporated with lithium and chloride ions, is unambiguously revealed using the emerging imaging technique of differential phase contrast STEM under a low dose. The lightest‐element Li/H configuration is resolved within framework cavities of PTI and significantly affects the electronic structure for photoabsorption. The atomic electric field of PTI crystal directly determined in real space provides a fundamental evidence for the chemical bonding of Li ions and adjacent atoms for the migration of photogenerated carriers. These results facilitate the comprehension on local atomic configuration and chemical bonding state of crystalline CNs and can lead to a deeper understanding of the photocatalytic mechanism.
Growth of Graphene Nanoflakes/h‐BN Heterostructures
Authors: Küster Kathrin , Hooshmand Zahra , Rosenblatt Daniel Pablo , Koslowski Sebastian , Le Duy , Starke Ulrich , Rahman Talat S. , Kern Klaus , Schlickum Uta 
Published: September 2021

Abstract2D materials such as graphene, hexagonal boron nitride (h‐BN), or transition metal dichalcogenides, and their heterostacks are gaining increasing interest because of their extraordinary properties, which can range from superconductivity to large charge carrier mobilities. In this paper, the electronic and structural modifications of h‐BN on Rh(111) are investigated by the intercalation of carbon forming graphene nanoflakes between the h‐BN and the Rh(111) surface. The carbon atoms—natural impurities in Rh bulk crystals—diffuse to the surface during the h‐BN growth and segregate there during cooling. The graphene nanoflakes are present at particular sites under the wires of the h‐BN nanomesh leading to an altered appearance of the Moiré pattern and modified electronic and chemical properties. Thus, a novel fabrication route of graphene nanoflakes located in a heterostack between Rh(111) and h‐BN is shown by steering the segregation of carbon impurities at the rhodium surface.
Rapid Synthesis of Bright, Shape‐Controlled, Large Single Crystals of Cs3Cu2X5 for Phase Pure Single (X = Br, Cl) and Mixed Halides (X = Br/Cl) as the Blue and Green Components for Printable White Light‐Emitting Devices
Authors: Zhou Zhicong , Li Yanyan , Xing Zengshan , Sung Herman H. Y. , Williams Ian D. , Li Zhi , Wong Kam Sing , Halpert Jonathan E. 
Published: September 2021

AbstractTernary copper halides have garnered significant interest for their bright, high quantum yield emission stemming from the radiative decay of self‐trapped excitons (STEs). Cesium copper halides have shown promise for use in optoelectronics, including light‐emitting devices (LEDs) for lighting and displays. To date several synthetic procedures for Cs3Cu2X5 (X = Cl, Br, and mixed Br/Cl) have been proposed for making nanocrystals, microcrystals, or polycrystalline thin films. Here, a synthetic method for making large single crystals (SCs) with millimeter dimensions in less than 30 min is presented. Phase pure mixed halide SCs are also produced and in‐depth structural analysis has been performed for the first time, definitively showing the site preferences for mixing chloride into the pure Cs3Cu2Br5 structure. Quantum yields for SCs of X = Cl and Br are 100% and 27% respectively, with long lifetimes and strong evidence of STE emission. This synthesis can be used to produce white light UV‐downconversion LEDs using ternary copper halides as the blue and green components along with the commercial red phosphor K2SiF6:Mn4+. These devices give a Commission Internationale de l'Éclairage (CIE) coordinate of (0.3327, 0.3342) and color rendering index of 90% at a color temperature of ≈5500 K.
Novel tool for assessing the quality of feedback in the emergency room (FEED‐ER)
Authors: Natesan Sreeja , Todd Brett , Hsu Robert S. , Ren Ronnie Kuo , Clark Ryan , Jara‐Almonta Geoff , Vissoci Joao Ricardo Nickenig , Narajeenron Khuansiri 
Published: September 2021

AbstractBackgroundThe Accreditation Council for Graduate Medical Education (ACGME) emphasizes constructive feedback as a critical component of residency training. Despite over a decade of using competency‐based milestone evaluations, emergency medicine (EM) residency programs lack a standardized method for assessing the quality of feedback. We developed two novel EM‐specific feedback surveys to assess the quality of feedback in the ER (FEED‐ER) from both the resident and the faculty perspectives. This study aimed to evaluate the surveys’ psychometric properties.MethodsWe developed FEED‐ER using a Likert scale with faculty and resident versions based on the ACGME framework and a literature review. The preliminary survey consisted of 25 questions involving the feedback domains of timeliness, respect/communication, specificity, action plan, and feedback culture. We conducted two modified Delphi rounds involving 17 content experts to ensure respondent understanding of the items, item coherence to corresponding feedback domains, thematic saturation of domain content, and time duration. A multicenter study was conducted at five university‐based EDs in the United States and one in Thailand in 2019. We evaluated the descriptive statistics of the frequency of responses, validity evidence, and reliability of FEED‐ER.ResultsA total of 147 EM faculty and 126 EM residents completed the survey. Internal consistency was adequate (Cronbach's alpha > 0.70) and test–retest reliability showed adequate temporal stability (ICC > 0.80) for all dimensions. Content validity was deemed acceptable (CVC > 0.80) for all items. From the 25 items of FEED‐ER, 23 loaded into the originally theorized dimensions (with factor loadings > 0.50). Additionally, the five feedback domains were found to be statistically distinct, with correlations between 0.40 and 0.60. The final survey has 23 items.ConclusionsThis is the first study to develop and provide validity evidence for an EM‐specific feedback tool that has strong psychometric properties, is reproducible and reliable, and provides an objective measure for assessing the quality of feedback in the ED.
Robin sequence without cleft palate: Genetic diagnoses and management implications
Authors: Weaver K. Nicole , Sullivan Bonnie R. , Balow Stephanie A. , Hopkin Sara , Chini Barbara A. , Pan Brian S. , Stottmann Rolf W. , Bender Patricia L. , Hopkin Robert J. , Zhang Xue , Saal Howard M. 
Published: September 2021

AbstractRobin sequence (RS), the triad of micrognathia, glossoptosis, and airway obstruction, is a major cause of respiratory distress and feeding difficulties in neonates. Robin sequence can be associated with other medical or developmental comorbidities in ~50% of cases (“syndromic” RS). As well, RS is variably associated with cleft palate (CP). Previous studies have not investigated differences in clinical characteristics of children with RS based on presence or absence of CP. We retrospectively reviewed 175 children with RS and compared genetic diagnoses, medical and developmental comorbidities, severity of airway obstruction, and feeding outcomes between those with and without CP. Strikingly, 45 of 45 (100%) children with RS without CP were classified as syndromic due to presence of comorbidities unrelated to RS, while 83 of 130 (64%) children with RS with CP were classified as syndromic. Among 128 children with syndromic RS, there were no differences in severity of airway obstruction, surgical intervention rate or type, or feeding outcome at 12 months based on CP status. Our findings support the conclusion that the pathogenesis of RS without CP is distinct from RS with CP and more likely to cause additional medical or developmental problems. Alternatively, children with RS without CP and without additional anomalies present may be under recognized.
Brain health: Key to health, productivity, and well‐being
Authors: Avan Abolfazl , Hachinski Vladimir ,   the Brain Health Learn and Act Group
Published: September 2021

AbstractBrain health is essential for physical and mental health, social well‐being, productivity, and creativity. Current neurological research focuses mainly on treating a diseased brain and preventing further deterioration rather than on developing and maintaining brain health. The pandemic has forced a shift toward virtual working environments that accelerated opportunities for transdisciplinary collaboration for fostering brain health among neurologists, psychiatrists, psychologists, neuro and socio‐behavioral scientists, scholars in arts and humanities, policymakers, and citizens. This could shed light on the interconnectedness of physical, mental, environmental, and socioeconomic determinants of brain disease and health. We advocate making brain health the top priority worldwide, developing common measures and definitions to enhance research and policy, and finding the cause of the decline of incidence of stroke and dementia in some countries and then applying comprehensive customized cost‐effective prevention solutions in actionable implementation units. Life cycle brain health offers the best single individual, communal, and global investment.
Recombinant human thrombopoietin improved platelet engraftment after autologous hematopoietic stem cell transplantation in patients with newly diagnosed multiple myeloma
Authors: Gu Jingli , Liu Junru , Li Xiaozhe , Zou Waiyi , Huang Beihui , Chen Meilan , Li Juan 
Published: September 2021

AbstractBackgroundTo evaluate the efficacy and safety of recombinant human thrombopoietin (rhTPO) for hematopoietic reconstitution after autologous stem cell transplant (ASCT) in patients with newly diagnosed multiple myeloma (NDMM).MethodThirty‐five cases with NDMM had been enrolled into a prospective clinical trial from March 2014. The hematopoietic reconstitution was compared between these 35 cases (rhTPO group) and 98 historic cases not receiving rhTPO (control group) after stem cell reinfusion.ResultsThirty‐five (100%) cases receiving rhTPO achieved both neutrophil and platelet engraftment within 30 days post‐transplant. The median time to neutrophil and platelet engraftment was the 10th day and 11th day after stem cell reinfusion, respectively. Multivariate analysis showed that rhTPO administration was an independent factor for accelerating platelet engraftment (HR 2.013, 95% CI 1.336–3.034, p = 0.001). Subgroup analysis showed that rhTPO improved platelet engraftment and alleviated platelet transfusion needs in patients with inadequate re‐infused CD34+ cell counts of <2 × 109/L. All the 35 patients tolerated rhTPO well. Survival analysis showed no decrease in time to progression (TTP) or overall survival (OS) by rhTPO administration.ConclusionrhTPO accelerated the platelet engraftment after ASCT in patients with NDMM with good tolerability and long‐term safety, especially for those patients with poor CD34+ cell reinfusion. rhTPO might be recommended to be used early after ASCT for patients with NDMM.
Principles of Combined Surgical Therapy for the Management of Peri‐Implantitis
Authors: Monje Alberto , Schwarz Frank 
Published: September 2021

Focused Clinical QuestionThe purpose of this technical note is to present the principles for combined therapy as well as to illustrate the step‐by‐step approach of this procedure to efficiently manage peri‐implantitis.SummaryPeri‐implantitis is the primary threat that compromises the longevity of dental implants. This entity is regarded as a biofilm‐mediated inflammatory condition. As such, the arrestment of disease is conditioned by the elimination of the etiological factor and the clinical resolution of inflammation by eliminating pathogenic pockets. It was suggested that the therapy of peri‐implantitis relies upon defect configuration. In this sense, defect configuration is, in part, conditioned by the dimensions of the alveolar bone and implant position. In the clinical basis, it is frequent to identify combined defects exhibiting area(s) where reconstructive therapy is inefficient due to uncontained defect morphology. These situations represent clinical indications for combined therapy.ConclusionsThis therapeutic modality is based on the combination of reconstructive therapy in the infraosseous defect component and surface modification for the area of the implant within the supracrestal component or outside the reparative potential.