bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mobilidade geográfica e carreira: um estudo sobre profissionais que migraram para os Estados Unidos.
Authors: Karawejczyk Tamara Cecilia 
Published: August 2021

Este estudo tem o intuito de investigar a mobilidade geográfica e a carreira dos profissionais que migram para os Estados Unidos. Para um melhor entendimento do assunto, as teorias relacionadas a noções de cultura e à cultura organizacional, incluindo a cultura americana, a trajetória de carreira profissional e a mobilidade geográfica oferecem o suporte necessário. O método de estudo escolhido foi o qualitativo exploratório e a técnica de análise foi a do discurso do sujeito coletivo, pois a intenção era a compreensão do todo e não a do individual. Para alcançar o objetivo, realizou-se entrevista com quinze profissionais de diferentes nacionalidades, que se enquadravam nas características da pesquisa, da empresa norte-americana Golden Gate. Como resultado desta investigação, foi categorizado em duas seções: perfil e trajetória de carreira dos entrevistados e mobilidade geográfica e trabalho nos Estados Unidos. A segunda seção permitiu a construção de seis categorias: motivos de saída do país de origem, motivos da escolha pelos Estados Unidos, conseguir emprego, dificuldades encontradas, motivos da permanência nos Estados Unidos e plano de carreira para o futuro.
Capital social en la perspectiva de la teoría de recursos y capacidades: un análisis bibliométrico
Authors: López Inda Karina Azucena , Alvarado Altamirano Sergio , Fong Reynoso Carlos , González Álvarez Eleazar 
Published: August 2021

En este estudio se realiza una primera aproximación a la perspectiva integrada del capital social bajo la Teoría de recursos y capacidades. Para ello se seleccionó la base de datos Scopus de la cual se extrajo la información necesaria para realizar un análisis bibliométrico de citación, palabras clave y autoría con el apoyo de las herramientas Excel y VOSviewer. Así mismo, se aplicó una revisión de contenido a los 46 documentos que arrojó la búsqueda. Los resultados confirman que el capital social es visto como un recurso firme que contribuye a mejorar el desempeño y la formación de ventajas competitivas sostenibles, además de estar estrechamente vinculado al uso del capital humano y desarrollo de capacidades como la innovación, el aprendizaje, la adaptación, así como a la gestión del conocimiento.
Palabras clave: Teoría de recursos y capacidades (TRC), capital social, ventaja competitiva, innovación
Códigos JEL: M10, M53, O12, O31
Recibido: 28/02/2019. Aceptado: 10/02/2020. Publicado: 27/04/2020
Pengaruh Penggunaan Facebook Terhadap Hasil Pemilihan Presiden 2019
Authors: Putra Delco Adia , Yazwardi Yazwardi , Fikri Muhammad Sirajudin 
Published: August 2021

Media Sosial Facebook sebagai Ruang Komunikasi Politik dalam pemilihan Presiden tahun 2019. Latar belakang masalah penelitian karena media merupakan masalah yang menjadi sorotan publik dan perlu mendapatkan perhatian untuk menanggulanginya. Penelitian ini berusaha menjawab bentuk pemanfaatan media sosial dalam pemilihan pemilihan Presiden tahun 2019, serta efektifitas komunikasi politik dalam media sosial facebook dalam konstalasi politik,. Jenis penelitian menggunakan tipe penelitian kualitatif yaitu prosedur penelitian yang menghasilkan data deskriptif. Sumber data yang diperoleh yaitu data primer dan data sekunder. Metode pengumpulan data dilakukan melalui wawancara, observasi dan melalui kajian literatur pustaka. Teknik analisis data yang digunakan yaitu teknik analisa secara kualitatif yang selanjutnya disajikan secara deskriptif. Adapun kerangka konseptual dan teoritis yang penulis gunakan yaitu teori komunikasi politik dan konsep media social.Hasil penelitian menunjukkan bahwa media sosial seperti facebook sangat berpengaruh pada komunikasi politik serta pemanfaatan media sosial berperan besar dalam Pemilihan pemilihan Presiden tahun 2019. Masing-masing tim sukses calon presiden beradu strategi kampanye melalui internet, terutama media sosial. Namun pemanfaatan media sosial untuk kampanye politik ternyata belum stabil, nampaknya belum bisa mengoptimalkan manfaat internet dan media sosial. Padahal media sosial ini selain sebagai sarana bersosialisasi atau pemasaran secara online, bisa dimanfaatkan pula sebagai alat kampanye politik yang terbilang praktis. Media sosial facebook sangat efektif dalam mengarahkan pemilih dalam memilih kandidat tertentu. Masing-masing kandidat memanfaatkan rekayasa media sosial dengan membuat grup-grup facebook. Media sosial facebook menjadi sarana bersosialisasi untuk mendulang suara dalam kontestasi politik serta menentukan opini yang menjadi perbincangan masyarakat.
Risk Factors for Hospital Mortality in Acute ST-Segment Elevation Coronary Syndrome Complicated by Cardiogenic Shock
Authors: Arsenicheva O. V. 
Published: August 2021

The aim. To study the risk factors for hospital mortality in patients with acute coronary syndrome with ST-segment elevation (STEACS) complicated by cardiogenic shock (CS).Materials and methods. A total of 104 patients with STEACS complicated by CS were studied. The follow-up group (group I) included 58 (55,8%) patients who died in hospital (mean age 71,8±7,31 years), the comparison group (group II) – 46 patients, who have been treated and discharged (mean age 59,5±6,18 years). All patients underwent general clinical studies, the level of troponins, lipids, glucose, creatinine in plasma was determined, electrocardiography and echocardiography were performed. Coronary angiography and percutaneous coronary intervention (PCI) were urgently performed. The method of binary logistic regression with the determination of the odds ratio and its 95% confidence interval for each reliable variable was used to identify risk factors for hospital mortality.Results. In group I patients with CS, compared with group II, patients over the age of 70 (32 (55,2%) vs 10 (22,7%), р=0,0004), with concomitant chronic kidney disease (32 (55,2%) vs 9 (19,6%), p=0,0002), postinfarction cardiosclerosis (30 (51,7%) vs 9 (19,6%), р=0,001) and chronic heart failure of III-IV functional class (32 (55,1%) vs 11 (23,9%), p=0,001) were significantly more often observed. Baseline levels of plasma leukocytes, troponin and creatinine were significantly higher in deceased patients with CS. Left ventricular ejection fraction below 40% was observed more often in the follow-up group than in the comparison group (46 (79,3%) vs 27 (58,7%), p=0,022). In group I, compared with group II, there was a higher incidence of three-vessel coronary lesions (36 (75%) vs 12 (26,1%), p=0,0001) and chronic coronary artery occlusion unrelated to STEACS (25 (52,1%) vs 12 (26,1%), р=0,009). The same trend was observed when assessing the average number of stenoses and occlusions of the coronary arteries. PCI was performed in 43 (74,1%) of the deceased and 43 (93,5%) of the surviving STEACS patients with CS (p=0,009). The follow-up group had a higher rate of unsuccessful PCI (30,2%) vs 3 (7%), р=0,001) and performed later than 6 hours after the onset of an angina attack (28 (65,1%) vs 6 (14%), р=0,0001).Summary. Hospital mortality in patients with STEMI complicated by CS was associated with the presence left ventricular ejection fraction less than 40%, three-vessel coronary lesion and performing PCI later than 6 hours from the beginning of the pain attack.
Study of Heart Rate Variability in Patients with Chronic Heart Failure and Chronic Obstructive Pulmonary Disease
Authors: Statsenko M. E. , Lopushkova Yu. E. 
Published: August 2021

Aim. To study heart rate variability (HRV) in patients with chronic heart failure (CHF) and chronic obstructive pulmonary disease (COPD) in relation to: blood oxygen saturation level, parameters of respiratory function (RPF), Nt – proBNP concentration in blood plasma.Materials and methods. We examined 128 outpatients of both sexes. The patients’ age ranged from 45 to 70 years. Group 1 – main (60 patients) with CHF of ischemic genesis of NYHA functional class II – III and GOLD COPD of I – III degree of airflow restriction (GOLD 2019 classification) in the stage of stable remission, group 2 – control group (63 patients), with isolated CHF. All patients with CHF, who were included in the study, had myocardial infarction (AMI) from 1 to 5 years ago. There were no statistically significant differences in the severity of CHF between groups 1 and 2.Results. In patients with CHF and COPD, in contrast to patients with isolated CHF, a significant prevalence of the frequency of occurrence of the hypersympathicotonic type of autonomic regulation was revealed. Significantly lower indicators of heart rate variability were in the group of patients with concomitant COPD in comparison with patients with isolated CHF. Statistically significant correlations were revealed between HRV parameters and RPF, parameters of blood oxygen saturation level, NT-proBNP concentration in blood. Multivariate regression analysis showed a significant dependence of HRV parameters on the parameters of HRV and the concentration of NT-proBNP in the blood in the group of patients with CHF and COPD.
Chest Pain in the Patient with Arteria Lusoria: A Case Report
Authors: Reznik E. V. , Kemez Yu. V. 
Published: August 2021

The most common anomaly of the aortic arch and its branches is the aberrant right subclavian artery – arteria lusoria. Usually, it produces dysphagia or dyspnea and chronic coughing.Our purposeis to underline that it is necessary to exclude the anomalies of the branches of the thoracic aorta, including arteria lusoria, in the patients with cardialgia of unknown origin.Clinical case.An 18-year-old female patient without a previously diagnosed chronic pathology was admitted to a hospital with chest pain after emotional stress for about an hour. The ECG revealed a sinus rhythm with a heart rate of 50 per minute, the normal direction of the electrical axis of the heart, the incomplete right bundle branch block, the negative T wave in the lead III. After excluding ischemic heart disease, acute coronary syndrome, pulmonary embolism, contrast-enhanced chest computed tomography revealed an aortic arch anomaly – a. lusoria.Conclusion.A. lusoria may manifest by cardiac pain. In patients with chest pain of unknown origin, it is advisable to include anomalies of the aorta and its branches, including the presence of the lusoria artery, in the range of differential diagnostics.
New mitochondrial genome resource for resolving the grey langur species complex
Authors: Hiremath Vipin , Khedkar Gulab , Jadhav Chandrakant Chandrakant , Sanil Raveendranathanpillai , Khedkar Chandraprakash , Prakash Bharathi 
Published: August 2021

Abstract
Among Indian primate species, the gray langur, is widely distributed and shows extraordinary morphological plasticity throughout its range of distribution. Various taxonomic assignments have been suggested and developed over the past century in resolving the systematic position of the gray langur. There was a substantial disagreements on number of species. To bring about some clarity, it has been proposed to use six morphotypes along with ecological niche modelling to form the basis of a taxonomic classification scheme for the grey langurs found in peninsular India. Nevertheless, the validation for these ambiguities in species numbers is necessary by employing independent tools and molecular data informatics. However, previous attempts at species authentication using molecular data usually rely on only one or a small number of genes. To develop a more reliable method for the reconstruction of phylogenetic relationships of these taxa, and to create an important genomic resource for future studies, we sequenced whole mitochondrial genome of the gray langur Seminopithicus hypoleucos. Our results substantiate the value of sequencing whole mitochondrial genomes for this purpose, and show that developing similar information for new members belonging to the species complex associated to the Hanuman langur clade is essential. Our study proposed a species boundary using different genomic locus to differentiate a species. This may aid to resolve taxonomy and systematic relationships of entire hanuman langur clade in the Indian subcontinent. Further data resource based validity is necessary in this regards.
Sudden Loss of Ovarian Function Exacerbate Cancer-related Fatigue in Patients with Ovarian Carcinoma
Authors: Cai Honghong , Chen Youguo , Shen Fangrong , Sun Huating , Wang Juan , Zhou Jinhua 
Published: August 2021

Abstract
Objective: We aimed to investigate whether ovarian cancer and cancer-related fatigue are associated with a sudden loss of ovarian dysfunction.Methods: In total, we retrospectively analyzed 211 survivors of ovarian carcinoma from the First Affiliated Hospital of Soochow University between January 2015 and January 2020. Fatigue was measured with the Cancer Fatigue Scale (CFS). Single and multiple linear regression were used to determine statistical differences.Results: Fatigue was reported in 206 of all completed questionnaires. Patients who had a menstrual period prior to treatment had a higher fatigue score. The CRF score was highest during the first two years after treatment and gradually decreased over time. Patients with sleep disorders became fatigued more easily. We identified a negative correlation between hemoglobin and CRF. There were no significant correlations between CRF, the number of chemotherapy cycles, the type of chemotherapy regimen, or the pathological subtype of ovarian cancer.Conclusion: CRF is common in ovarian cancer patients and improve CRF are important for improving the quality of life. The fatigue experienced by patients with ovarian cancer may be related to the deprivation of sex hormones. It may be prudent to add such hormones to the treatment regimen in order to improve CRF.
Degradation of Methyl Violet over Fenton-Like Hydroxyapatite Catalysts, Kinetics and Thermodynamics Studies
Authors: Roumila Yasmina , Meziani Djaafar , Debaghi Saadia , Abdmeziem Kaïssa 
Published: August 2021

Abstract
Hydroxyapatite (HA), a calcium hydroxyphosphate was prepared via precipitation method and used as a catalyst in a Fenton like process for methyl violet (MV) dye degradation. This study is aimed to evaluate the effect of hydrogen peroxide concentration, HA dose, initial pH, temperature and MV concentration on the catalyst performance to find out the optimum conditions leading to maximum efficiency of the Fenton process. The results showed that MV dye with a concentration of 20 mg L-1 can be removed within just 10 minutes at the optimal conditions of 36 mmol L–1 H2O2 and 2.5 g L–1 HA at pH of 6.65 and T = 48 °C). The experimental outcome of this study also demonstrates that HA displayed a good recyclability over three cycles; while the use of scavenger highlighted that the hydroxyl radical HO• was the main active species for MV degradation. The catalytic tests result of MV dye degradation were analyzed by the first-order, second-order and Benhnajady-Modirshahla-Ghanbery (BMG) kinetic models, those showing that the Fenton like reaction follows the first-order and BMG models. The activation energy of the reaction and the values of thermodynamic parameters such as standard enthalpy (ΔH*0), entropy (ΔS*0) and Gibbs free energy (ΔG*0) were also evaluated. Those results revealed that the degradation of MV over the as-synthesized material is an endothermic and non-spontaneous process.
Computational Study of Novel Natural Inhibitors Targeting 3-Phosphoinositi-Dependent Protein Kinase 1(PDK1)
Authors: Zhong Sheng , Guo Zhen , Dou Gaojing , Lv Xiaye , Wang Xinhui , Wu Bo , Wang Hongyu , Jiang Yuting , Liu Xiaoxia , Hou Shuya , Liang Luodan , Chen Zhenghe , Mou Yonggao 
Published: August 2021

Abstract
Objective To screen ideal lead compounds with potential inhibition of 3-phosphoinositi-dependent protein kinase 1 (PDK1) from ZINC15 database, which is beneficial to drug design and improvement.Methods The Discovery Studio 4.5 computer-aided virtual screening technique was used to screen potential inhibitors of PDK1. Libdock was used for virtual screening and scoring of candidate compounds, ADME module was used for physical and chemical properties and toxicity analysis, and CDOCKER module was used for molecular docking analysis. The binding affinity of ligand-PDK1 was studied through molecular docking, and the stability of ligand-PDK1 in the natural environment was analyzed through molecular dynamics simulation.Results Two natural compounds ZINC00000157721 and ZINC000034189841 were screened from ZINC15 database. These two compounds have no CYP2D6 inhibition, easy to pass the blood-brain barrier, no hepatotoxicity, high binding affinity with PDK1, higher stability in the natural environment than positive drug BX-795, and stable existence.Conclusions The results show that ZINC00000157721 and ZINC000034189841 are ideal and safe lead compounds and have a potential inhibitory effect on PDK1. These compounds are safe candidates and may provide the basis and premise for the design and optimization of specific PDK1 inhibitors.
Entanglement of a System of an Indirectly Linked Two-Coupled-Cavity
through an Optical Fiber Cable for Single Excitation Atomic States in
the Presence of an External Field
Authors: Hanoura Sadek Ahmed 
Published: August 2021

Abstract
The dynamics of the quantum entropies of a system of two cavities coupled by an optical fiber cable, each cavity contains a two-level atom interacting with a single electromagnetic field in addition to an external classical field, is investigated. Under canonical transformations, the considered Hamiltonian is diagonalized. Effective Hamiltonians in three different limiting regimes: namely large optical fiber cable coupling bstrength, large detunig, and comparable detuning and optical fiber cable coupling strength, are derived. The ith ¯ -tom are respectively prepared in the superposition coherent and the ground states while the fields are prepared in the vacuum states. An analytical expression for the solution of the Schr¨odinger equation for each dispersive is derived. The degree of entanglement (DEM) is studied by using von Neumann atomic entropies. The influences of both the optical fiber cable coupling strength and the detuning on the evolution of the DEM ”their values are closely chosen to be compatible with the imposed restrictions for the applications of the different regimes” are analyzed. General conclusions reached are illustrated by numerical results.
Functional analysis of Ectodysplasin-A mutations in X-linked non-syndromic hypodontia and possible involvement of X-chromosome inactivation
Authors: Pan Yuhua , Lu Ting , Peng Ling , Zeng Qi , Huang Xiangyu , Wu Buling , Xiong Fu 
Published: August 2021

Abstract
Background: Mutations of the Ectodysplasin-A (EDA) gene are generally associated with syndrome hypohidrotic ectodermal dysplasia or non-syndromic tooth agenesis. The influence of EDA mutations on dentinogenesis and odontoblast differentiation have not been reported. The aim of this study was to identify genetic clues for the causes of familial non-syndromic oligodontia and explore the underlying mechanisms involved, while focusing on the role of human dental pulp stem cells (hDPSCs). Materials and Methods: Candidate gene sequences were obtained by PCR amplification and Sanger sequencing. Functional analysis was conducted, and the pathogenesis associated with EDA mutations in hDPSCs was investigated to explore the impact of the identified mutation on the phenotype. Capillary electrophoresis (CE) was used to detect X chromosome inactivation (XCI) in the blood of female carriers. Results: In this study, we identified an EDA mutation in a Chinese family：the missense mutation c.1013C>T (Thr338Met). Transfection of hDPSCs with a mutant EDA lentivirus decreased the expression of EDA and dentin sialophosphoprotein (DSPP) compared with transfection of control EDA lentivirus. Mechanistically, mutant EDA inhibited the activation of the NF-κB pathway. The CE results showed that symptomatic female carriers had a skewed XCI with a preferential inactivation of the X chromosome that carried the normal allele. Conclusions: In summary, we demonstrated that EDA mutations result in non-syndromic tooth agenesis in heterozygous females and that, mechanistically, EDA regulates odontogenesis through the NF-κB signalling pathway in hDPSCs. Due to the large heterogeneity of tooth agenesis, this study provided a genetic basis for individuals who exhibit similar clinical phenotypes.
Production And Characterization of Transportation Fuels From Domestic Plastic Wastes And Mixed Virgin Plastics By Low- Cost Catalytic Pyrolysis
Authors: Ghodke Praveen Kumar , Moorthy Krishna , Sharma Amit Kumar , Chen Wei-Hsin 
Published: August 2021

Abstract
With increasing population, modernization, and industrialization, plastics usage is growing daily and results in vast plastic waste. Recycling these plastic wastes to hydrocarbon fuels is challenging due to their different chemical structures, long-chain polymeric compositions, and decomposition/thermal behavior. In the present manuscript, the pyrolysis of domestic plastic waste was carried out at 473 - 973 K in a fixed bed tubular reactor and compared with individual virgin plastics, i.e. HDPE (High-density polyethylene), LDPE (Low-density polyethylene), PP (Polypropylene), and their mixture of (virgin mixed plastic). The experiments were also performed using a low-cost catalyst (mineral clay) to maximize hydrocarbon fuels. At identified optimum operating conditions, the domestic plastic waste and mixed virgin plastics yielded 73.1 wt% and 81.6 wt% liquid hydrocarbons along with 16.9 wt% and 25.5 wt.% pyrolysis gas, respectively. The composition of liquid fuels was analyzed using FTIR and GC-MS in detail, revealing a wide variety of hydrocarbons disbursement in the range of C8–C20. In addition, fuel properties of liquid fuels such as viscosity, density, fire and flash point, pour point, and calorific value was analyzed according to ASTM methods and found to be satisfactory. Based on chemical composition and fuel properties, liquid fuels derived from domestic plastic wastes showed 78.05%, and 61.86 % similarity with diesel, and jet fuels respectively. Non-condensable gases, which mainly consist of ethane and propene with minor amounts of hydrogen and methane, have been identified to be ideal for spark-ignition engine (SI) engines. This study offers a unique technique for converting waste plastics into transportation jet fuel using an affordable catalyst.
Prophylactic Protection Against Respiratory Viruses Conferred by a Prototype Live Attenuated Influenza Virus Vaccine
Authors: Rathnasinghe Raveen , Salvatore Mirella , Zheng Hongyong , Jangra Sonia , Kehrer Thomas , Mena Ignacio , Schotsaert Michael , Muster Thomas , Palese Peter , Garcia-Sastre Adolfo 
Published: August 2021

Abstract
The influenza A non-structural protein 1 (NS1) is known for its ability to hinder the synthesis of type I interferon (IFN) during viral infection. Influenza viruses lacking NS1 (ΔNS1) are under clinical development as live attenuated human influenza virus vaccines and induce potent influenza virus-specific humoral and cellular adaptive immune responses. Attenuation of ΔNS1 influenza viruses is due to their high IFN inducing properties, that limit their replication in vivo. This study demonstrates that pre-treatment with a ΔNS1 virus results in an immediate antiviral state which prevents subsequent replication of homologous and heterologous viruses, preventing disease from virus respiratory pathogens, including SARS-CoV-2. Our studies suggest that ΔNS1 influenza viruses could be used for the prophylaxis of influenza, SARS-CoV-2 and other human respiratory viral infections, and that an influenza virus vaccine based on ΔNS1 live attenuated viruses would confer broad protection against influenza virus infection from the moment of administration, first by non-specific innate immune induction, followed by specific adaptive immunity.