bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-term association of pregnancy and maternal brain structure: the Rotterdam Study
Authors: Aleknaviciute Jurate , Evans Tavia E. , Aribas Elif , de Vries Merel W. , Steegers Eric A.P. , Ikram M. Arfan , Tiemeier Henning , Kavousi Maryam , Vernooij Meike W. , Kushner Steven A. 
Published: February 2021

ABSTRACTThe peripartum period is the highest risk interval for the onset or exacerbation of psychiatric illness in women’s lives. Notably, pregnancy and childbirth have been associated with short-term structural and functional changes in the maternal human brain. Yet the long-term effects of parity on maternal brain structure remain unknown. Therefore, we utilized a large population-based cohort to examine the association between parity and brain structure. In total, 2,835 women (mean age 65.2 years; all free from dementia, stroke, and cortical brain infarcts) from the Rotterdam Study underwent magnetic resonance imaging (1.5 T) between 2005 and 2015. Associations of parity with global and lobar brain tissue volumes, white matter microstructure, and markers of vascular brain disease were examined using regression models. We found that parity was associated with a larger global gray matter volume (β= 0.14, 95% CI = 0.09-0.19), a finding that persisted following adjustment for sociodemographic factors. A non-significant dose-dependent relationship was observed between a higher number of childbirths and larger gray matter volume. The gray matter volume association with parity was globally proportional across lobes. No associations were found regarding white matter volume or integrity, nor with markers of cerebral small vessel disease. The current findings indicate that pregnancy and childbirth are associated with robust long-term changes in brain structure involving larger global gray matter volume that persists for decades. Taken together, these data provide novel insight into the impact of motherhood on the human brain.
Environmental DNA in a Global Biodiversity Hotspot: Lessons from Coral Reef Fish Diversity Across the Indonesian Archipelago
Authors: Marwayana Onny N. , Gold Zachary , Barber Paul H. 
Published: February 2021

AbstractIndonesia is the heart of the Coral Triangle, the world’s most diverse marine ecosystem. Preserving the biological and economic value of this marine biodiversity requires efficient and economical ecosystem monitoring, yet our understanding of marine biodiversity in this region remains limited. This study uses environmental DNA (eDNA) to survey fish communities across a pronounced biodiversity gradient in Indonesia. A total of 12,939,690 sequence reads of MiFish12SrRNA from 39 sites spanning 7 regions of Indonesia revealed 4,146 Amplified Sequence Variants (ASVs). Regional patterns of fish diversity based on eDNA broadly conformed to expectations based on traditional biodiversity survey methods, with the highest fish biodiversity in Raja Ampat and generally lower diversity in Western Indonesia. However, eDNA performed relatively poorly compared to visual survey methods in site-by-site comparisons, both in terms of total number of taxa recovered and ability to assign species names to ASVs. This result stands in a stark contrast to eDNA studies of temperate and tropical ecosystems with lower diversity. Analyses show that while sequencing depth was sufficient to capture all fish diversity within individual seawater samples, variation among samples from individual localities was high, and sampling effort was insufficient to capture all fish diversity at a given sampling site. Interestingly, mean ASVs recovered per one-liter seawater was surprisingly similar across sites, despite substantial differences in total diversity, suggesting a limit to total ASVs (~200) per one-liter eDNA sample. Combined, results highlight two major challenges of eDNA in highly diverse ecosystems such as the Coral Triangle. First, reference databases are incomplete and insufficient for effective ASV taxonomic assignment. Second, eDNA sampling design developed from lower diversity temperate marine ecosystems are inadequate to fully capture diversity of biodiversity hotspots like the Coral Triangle.
VAMP2 AND SYNAPTOTAGMINS ARE RELATIVELY IMMOBILE ON CHROMAFFIN GRANULE MEMBRANES: IMPLICATIONS FOR MEMBRANE FUSION AND FUSION PORE EXPANSION
Authors: Abbineni Prabhodh S. , Briguglio Joseph S. , Chapman Edwin R. , Holz Ronald W. , Axelrod Daniel 
Published: February 2021

AbstractAlthough many of the proteins of secretory granules have been identified, little is known about their molecular organization and diffusion characteristics. Granule-plasma membrane fusion can only occur when proteins that enable fusion are present at the granule-plasma membrane contact. Thus, the mobility of granule membrane proteins may be an important determinant of fusion pore formation and expansion. To address this issue, we measured the mobility of (fluorophore-tagged) vesicle associated membrane protein 2 (VAMP2), synaptotagmin 1 (Syt1), and synaptotagmin 7 (Syt7) in chromaffin granule membranes in living chromaffin cells. We used a method that is not limited by standard optical resolution. A bright flash of strongly decaying evanescent field (∼80 nm exponential decay constant) produced by total internal reflection (TIR) was used to photobleach GFP-labeled proteins in the granule membrane. Fluorescence recovery occurs as unbleached protein in the granule membrane distal from the glass interface diffuses into the more bleached proximal regions, thereby enabling the measurement of diffusion coefficients. The studies revealed that VAMP2, Syt1, and Syt7 are relatively immobile in chromaffin granules membranes with diffusion constants of ≤ 3 × 10−10 cm2/s. Utilizing these diffusion parameters and the known density of VAMP2 and Syt 1 on synaptic vesicles, we estimated the time required for these proteins to arrive at a nascent fusion site to be tens of milliseconds. We propose that the mobilities of secretory granule SNARE and Syt proteins, heretofore unappreciated factors, influence the kinetics of exocytosis and protein discharge.Significance StatementIn eukaryotic cells, secretory vesicles fuse with the plasma membrane to secrete chemical transmitters, hormones and proteins that enable diverse physiological functions including neurotransmission. Fusion proteins need to be assembled at the fusion site in sufficient number in order to enable membrane fusion. However, the diffusion characteristics of fusogenic proteins on secretory vesicles remained unknown. Here we used a novel method not limited by standard optical resolution to measure the diffusion of VAMP2 and synaptotagmins on chromaffin granule membranes. We found they have limited mobility. The time required for these proteins to reach the granule-plasma membrane contact site suggests that their limited mobility likely influences the kinetics of membrane fusion and subsequent fusion pore expansion.
Corrosion mechanism of a new-type low-alloy corrosion resistant steel containing Sb used in acid environment
Authors: Yang Ying , Wu Wei , Cheng Xuequn , Zhao Jinbin , Zhaoal Baijie , Li Xiaogang 
Published: February 2021

Purpose
This study aims to develops a new-type low-alloy corrosion resistant steel containing Sb and investigate the corrosion mechanism of this new-type low-alloy steel.

Design/methodology/approach
Energy dispersive spectrometer, X-ray photoelectron spectroscopy, X-Ray diffraction and scanning electron microscopy were used to evaluate the corrosion resistance of the rust layers formed on these samples. Laser confocal microscopy was used to observe the corroded surfaces of the steels.

Findings
Results showed that Sb added can consume H+ in the solution, thereby preventing the oxygen reaction to slow down the corrosion rate. Meanwhile, a stable and insoluble substance (Sb2O3) in the acidic solution would be produced when the reaction of the product of Sb and H+ with the enough dissolved oxygen in the solution. Due to the precipitation of Sb2O3 and iron oxyhydroxides, the rust layer of Sb-containing steel became more uniform and compact, which resulted in better corrosion resistance in acid environment.

Originality/value
In this study, a new-type acid resistant low-alloy steel containing Sb was developed. Compared with the results, the corrosion mechanism of the new-type low-alloy steel in acid environment was discussed.
The costs of COVID-19 and the cost-effectiveness of testing
Authors: González López-Valcárcel Beatriz , Vallejo-Torres Laura 
Published: February 2021

Purpose
This paper aims to provide an estimation of the costs of the coronavirus (COVID-19) pandemic with a special focus on Spain. Costs include macroeconomic costs of foregone gross domestic product (GDP) attributable to the pandemic and the direct and indirect costs of prevention, treatment and lost productivity. This study also analyzes the cost-effectiveness of the test-tracking-quarantine (TTQ) strategy in Spain.

Design/methodology/approach
The macroeconomic costs of foregone GDP attributable to the pandemic are estimated for different countries and areas by comparing the present GDP forecasts for 2020 and 2021 with counterfactuals estimated before the COVID-19 crisis aftermath. The total cost of the COVID-19 for Spain in 2020 was obtained using the cost of illness approach with a bottom-up process. A cost-effectiveness analysis of the TTQ strategy in Spain is based on the estimation of the total costs of TTQ and the health gains and avoided health-care costs associated with the TTQ strategy. A sensitivity analysis explores the consequences of uncertainty in key parameters.

Findings
The GDP cost of the COVID-19 is by far larger than all the other components of the cost. The global cost of the Covid-19 crisis in 2020–2021 is estimated at 14% of 2019 GDP (around 12,206 mm$). In the specific case of Spain, it amounts to 24% of the 2019 GDP; which is 397.3 m €. Spain is and will be by far the European country most economically affected by the pandemic. In Spain 2020, the GDP cost accounts for 94.7% of the total cost of the COVID-19 and health-care direct costs are only 2.14%. TTQ is a dominant strategy in Spain. For each euro spent on it, 7 euros will be recovered only in terms of saved health-care resources.

Research limitations/implications
Given the large degree of uncertainty and the fast-evolving nature of the epidemic, a number of assumptions are required to arrive at the estimates provided in this study. The results were found to be robust to the assumptions applied.

Practical implications
TTQ is a key strategy for the contention of the epidemy and it is justified from the economic perspective.

Originality/value
This is the first estimation of the cost of the COVID-19 and the cost-effectiveness of the TTQ strategy for Spain.
Proposed guidelines for treatment of recurrent failures for sustainability of results in the post-project improvement stage process
Authors: Almeida Caio Melo , Araujo Fernando Oliveira , Abreu Chrystyane Gerth Silveira , Batista Haydee Maria Correia da Silveira 
Published: February 2021

PurposeThe maintenance of process improvement programs within organizations is not an easy task. Some processes do not maintain the results achieved with the improvement project and again present low performance shortly after completion of the project. This paper aims to identify the socio-technical causes responsible for the loss of process performance after applying improvement projects, in order to support the mitigation of the problem.Design/methodology/approachA systematic review of the literature was carried out, which allowed the selection of 28 articles. The empirical stage used the benchmarking technique, along a large Brazilian mining company with an international standard of production and quality. This organization has been using improvement projects for more than ten years.FindingsThe research complements the literature regarding the prioritization of the 26 identified failures and the identification of seven new failure factors and two resources. Findings in this study can be an inspiration for other organizations, considering the similarity of methodological aspects of improvement projects since internationally standardized methodologies such as Six Sigma, Lean, Kaizen and 5S are used.Originality/valueThe research presented a proposal of guidelines that corroborate to the mitigation of loss of process performance after improvement project.
Voremetur Project: proposal for the digital cataloguing of museum objects on media art
Authors: García-López Fátima , Martínez-Cardama Sara , Morales-García Ana María 
Published: February 2021

Purpose
The purpose of this paper is to describe the creation of a catalogue of museum objects associated with two media art collections. The proposal was formulated under the Voremetur Project “Vocabularios para una Red de Archivos y Colecciones de Media Art y sus efectos: metaliteracy y turismo de conocimiento” (thesauri for networked media art archives and collections and their effects: metaliteracy and knowledge tourism) (HAR2016-75949-C2-1-R). Collection characteristics and typologies are discussed along with the difficulties encountered and the interoperability of the platform chosen with other Web resources that foster visibility.

Design/methodology/approach
This paper describes a case study and a review of the protocols and standards used to catalogue media art collections. Digitised descriptions were processed with Omeka software in conjunction with the expanded Dublin Core metadata schema. This paper also reviews the literature on the conceptualisation of these collections and the challenges involved in their conservation and management.

Findings
The result was the creation of a digital repository for two media art collections: one linked to Espacio P; and the other the outcome of digitising part of the MIDECIANT collection (Archivo Media ART AEMA).

Originality/value
The methodology innovates the description and analysis of museum objects on media art in Spain. The proposed cataloguing method can be replicated and used to describe similar collections and lays the grounds for creating a Spanish network of media art archives and collections.
A 23.3 dBm CMOS power amplifier with third-order gm cancellation linearization technique achieving OIP3 of 34 dBm
Authors: Mariappan Selvakumar , Rajendran Jagadheswaran , Mohd Noh Norlaili , Yusof Yusman , Kumar Narendra 
Published: February 2021

Purpose
The purpose of this paper is to implement a highly linear 180 nm complementary metal oxide semiconductor (CMOS) power amplifier (PA) to meet the stringent linearity requirement of an long term evolution (LTE) signal with minimum trade-off to power added efficiency (PAE).

Design/methodology/approach
The CMOS PA is designed in a cascaded dual-stage configuration comprises a driver amplifier and a main PA. The gate voltage (VGS) of the driver amplifier is tuned to optimize its positive third-order transconductance (gm3) to be canceled with the main PA’s fixed negative gm3. The gm3 cancellation between these stages mitigates the third-order intermodulation product (IMD3) that contributes to enhanced linearity.

Findings
For driver’s VGS of 0.82 V with continuous wave signal, the proposed PA achieved a power gain of 14.5 dB with a peak PAE of 31.8% and a saturated output power of 23.3 dBm at 2.45 GHz. A maximum third-order output intercept point of 34 dBm is achieved at 20.2 dBm output power with a corresponding IMD3 of −33.4 dBc. When tested with a 20 MHz LTE signal, the PA delivers 19 dBm maximum linear output power for an adjacent channel leakage ratio specification of −30 dBc.

Originality/value
In this study, a novel cascaded gm3 cancellation technique has been implemented to achieve a maximum linear output power under modulated signals.
Professional competence and attitudes of library personnel towards digital services in selected university libraries in Nigeria
Authors: Atanda Abiodun Daniel , Owolabi Kehinde Abayomi , Ugbala Chukwuemeka Peter 
Published: February 2021

Purpose
The purpose of this paper is to investigate the professional competence and attitude of library personnel towards digital services in selected university libraries in Nigeria. Despite the evolution of digital technologies in university libraries, as well as massive investment and research on digital libraries particularly in developed countries, it has been observed that many university libraries in Nigeria are still relatively reliant on traditional library services which no longer serve and satisfy the twenty-first-century users’ needs.

Design/methodology/approach
The population of the study comprised all the 196 library personnel from the 5 purposively selected university libraries in Nigeria. The total enumeration sampling method was adopted; while the questionnaire was the main instrument for data collection.

Findings
The findings of the study revealed that internet service was the most available digital service in libraries. It further revealed that most of the library personnel have requisite proficiency skills in basic computer operations. However, inadequate power supply was the major problem affecting digital services in the university libraries.

Research limitations/implications
The study is limited to a specific geographical area and selected university libraries in Ogun State, Nigeria. Accordingly, further studies need to be carried out on the same or similar subject matter, in other states or regions in Nigeria.

Practical implications
The need for library personnel to acquire relevant information and communication technology skills and develop a positive attitude that will enable them to render effective digital library services in the university libraries. Apart from this, university libraries should also strive to train users on how to access digital services in the libraries.

Originality/value
This study is novel, in the sense that it is the first of its kind to examine the professional competence and attitude of library personnel towards digital services in university libraries in Nigeria. The paper reported the necessary skills that library staffs need to demonstrate to effectively use various digital resources in the libraries to meet the information needs of their users.
Scientometric analysis of BIM adoption by SMEs in the architecture, construction and engineering sector
Authors: Makabate Choeu Tshepisho , Musonda Innocent , Okoro Chioma Sylvia , Chileshe Nicholas 
Published: February 2021

PurposeBuilding information modelling (BIM) has had a significant impact on the architecture, engineering and construction (AEC) sector in the past several years. However, not much is published concerning small and medium-sized enterprises (SMEs) adopting BIM in the construction industry. To address this knowledge gap, a complete and in-depth literature review of the adoption of BIM by SMEs in the AEC sector is conducted in this study. The paper also provides a comprehensive review of the mainstream studies of adoption of BIM in the AEC organisations.Design/methodology/approachBased on a five-stage literature review, 54 articles on the adoption of BIM by SMEs from the period 2009 to 2019 were critically analysed from the following three perspectives: (1) the number of articles produced; (2) the research focus and (3) the author's contributions. The techniques of the visualisation of similarities (VOSviewer) software were used to analyse the citation networks of the 54 articles as identified.FindingsFrom the analysis, it was established that the number of studies on BIM adoption by SMEs in the reviewed journals has not been increasing and not many articles are available. The finding makes the argument that BIM adoption by SMEs is not a focus point but rather the adoption and implementation of BIM is generalised in the AEC sector. In addition, the results revealed that most of the published articles come from the United Kingdom (UK). However, this finding is hardly surprising due to the requirements in the UK, which have made the adoption of BIM mandatory on all publicly funded projects and are at level 2 BIM. The other highly ranked countries by origins of studies on the adoption of BIM by SMEs were found to be Australia and the United States of America (USA), all of which are developed nations or economies. Some key BIM in SME research trends (adoption, enforcement, benefits, strategies, skills gap, awareness, education and training, and technology) were identified and evaluated.Research limitations/implicationsThe results presented in this journal are only applicable to SMEs in the AEC sector. As a result of little available literature on the adoption of BIM in developing countries, the articles have been drawn from developed countries. The dataset was mainly extracted from the Scopus database for the analysis.Originality/valueAn accomplished series content analysis of the implementation and adoption of BIM by SMEs from international construction journals were reported. The study makes significant and emergent contribution by building on the foundation of BIM research in SMEs as well as providing a reference point for the interpretation of findings, as well as directions for future research.
Equity gap in construction contracting: identification and ramifications
Authors: Zhu Liuying , Cheung Sai On 
Published: February 2021

PurposeThis study conceptualizes the equity gap (EG) in construction contracting and examines its impact on project performance.Design/methodology/approachThe identification of EG was first summarized from a literature review. A conceptual framework that included EG elements of information, risks, expected return and power asymmetry was then proposed. A study of the Hong Kong–Zhuhai–Macau Bridge supported the existence of EG. The framework was further refined by incorporation of 21 EG identifications. To examine the reliability of the framework, data were collected from 106 senior project professionals to evaluate the extent to which EG identification occurred in their projects. A Partial Least Square–Structural Equation Modeling (PLS-SEM hereafter) analysis was conducted on the collected data.FindingsThe proposed framework was deemed statistically significant. Furthermore, no significant differences were detected between the developer and contractor. The concepts of asset and process specificities suggested that the unaddressed EG may be met with retaliatory behaviors, such as noncooperation, procrastination, opportunism and withdrawal, as the physical works proceed. These behaviors may also hamper project performance.Practical implicationsTo address the EG ex post, it is suggested that relational incentives to balance the power differential be set, reallocation of risks and return and enhancing task programmability for ease of monitoring and performance evaluation.Originality/valueThis study investigates the downside of the EG between the contracting parties. The proposed EG framework informs the project management of critical EG elements and possible methods to narrow the gap ex post. Practical suggestions are also provided to manage construction contracts in general and in the use of incentive schemes to address EG.