bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spectral Artificial Vision Endoscopy for Assisting the Differential Diagnosis of Endometrial Polyps, In Vivo
Authors: F Gkrozou , C Rossos , A Tsapras , N Kortsalioudakis , O Tsonis , C Balas , M Paschopoulos 
Published: May 2021

We are the first to present results from a pilot clinical study designed for the purpose of establishing spectral mapping patterns, as a potential novel imaging assay for identifying and discriminating between functional and nonfunctional endometrial polyps in vivo. The Spectral Artificial Vision Endoscope (SAVE) was used and validated in this study. The SAVE system, adapted to a regular hysteroscope, was able to operate in several imaging modes, including color imaging, infrared imaging, narrow band imaging and spectral mapping, all acquired at a video rate and simultaneously. The spectral maps generated by the SAVE system for 28 patients with endometrial polyps displayed characteristic patterns capable of discriminating functional from nonfunctional polyps with remarkable consistency (Spearman R=0.912, p<10-6). These preliminary clinical validation results highlighted the great potential of the in vivo spectral mapping imaging modality as an adjunct tool to conventional color camera-based hysteroscopy, offering improved and quantitative diagnosis.
Association of +505A>G Polymorphism at TAFI Gene with Recurrent Miscarriage in Iranian Women
Authors: Alivand Razieh , Abdi Fatemeh , Dehghani-Ashkezari Mahmood , Neamatzadeh Hossein , Ekraminasab Sedigheh 
Published: May 2021

Background: Recurrent miscarriage (RM) is one of the major problems of public health globally. The thrombin-activatable fibrinolysis inhibitor (TAFI) gene is a plasma zymogen that regulates both fibrinolysis and inflammation. Genetic variants within TAFI gene are presumed to be associated with development of RM. This case-control study aimed to investigate the association of TAFI +505A>G polymorphism with RM in Iranian women referred to Meybod Genetic Center.
Methods: Fifty women with RM (at least 2 miscarriages) and 50 healthy women with no history of miscarriage or other fertility complications were participated in this study. The TAFI +505A>G polymorphism was genotyped by allele specific PCR (AS-PCR) assay.
Results: The mean age of cases with RM and controls was 27.25 ± 4.31 and 28.42 ± 3.22 years, respectively. The frequency of GG genotype and G allele was 0.00% in patients and controls. There was no significant difference between RM cases and controls in terms of +505A>G genotypes and alleles.
Conclusion: This study results indicated that there was no significant relationship between the TAFI +505A>G polymorphism and RM risk in Iranian women. However, further rigorous, studies with a larger sample size and different ethnicity are necessary to confirm our findings.
A Meta-Analysis for Association of ACE I/D Polymorphism with Susceptibility to Preterm Birth
Authors: Bahrami Reza , Dastgheib Seyed Alireza , Golestanpour Hossein , Akbarian Elahe , Emarati Alireza , Jafari-Nedooshan Mohammad , Neamatzadeh Hossein 
Published: May 2021

Background: Preterm birth is one of the main contributors to newborn mortality, morbidity, and hospitalization in the first year of life globally. To date, several numbers of studies have reported that Angiotensin-Converting enzyme Insertion/Deletion polymorphism (ACE I/D) is linked with preterm birth. But those results are conflicting. Thus, we carried out this meta-analysis to summarize the existing data and evaluated the association.
Methods: All eligible studies were collected from PubMed, Scopus, SciELO, MedRxiv, SID, China National Knowledge Infrastructure (CNKI), and Chinese Biomedical Literature Database (CBLD) up to 01 March 2021. The pooled odds ratios (ORs) and 95% confidence interval (CIs) under all five genetic models were calculated using either random-effects or fixed-effects models dependent on study heterogeneity.
Results: A total of five case-control studies with 480 preterm birth cases and 702 healthy subjects were included. Pooled data showed that the ACE I/D polymorphism was significantly associated with increased risk of preterm birth under the allele model (I vs. D: OR = 1.219, 95% CI 1.023-1.453, P = 0.027), homozygote model (II vs. DD: OR = 0.662, 95% CI 1.149-2.385, P = 0.007), and recessive model (DD vs. DI+II: OR = 0.707, 95% CI 1.082-1.948, P = 0.013). Stratified analysis by ethnicity indicated that the ACE I/D polymorphism was significantly associated with preterm birth in Caucasian descendants.
Conclusion: Our pooled data revealed that ACE I/D polymorphism is associated with the risk of preterm birth. However, larger and more rigorous studies among different populations are needed to evaluate the association with preterm birth.
Stability Analysis of HIV/AIDS Model with Educated Subpopulation
Authors: Habibah Ummu 
Published: May 2021

We had constructed mathematical model of HIV/AIDS with seven compartments. There were two different stages of infection and susceptible subpopulations. Two stages in infection subpopulation were an HIV-positive with consuming ARV such that this subpopulation can survive longer and an HIV-positive not consuming ARV. The susceptible subpopulation was divided into two, uneducated and educated susceptible subpopulations. The transmission coefficients from educated and uneducated subpopulations to infection stages were where (( and ) ( and )) In this paper, we consider the case of and were zero. We investigated local stability of the model solutions according to the basic reproduction number as a threshold of disease transmission. The disease-free and endemic equilibrium points were locally asymptotically stable when and respectively. To support the analytical results, numerical simulation was conducted.
Trace of Positive Integer Power of Squared Special Matrix
Authors: Rahmawati Rahmawati , Citra Aryati , Aryani Fitri , Marzuki Corry Corazon , Muda Yuslenita 
Published: May 2021

The rectangle matrix to be discussed in this research is a special matrix where each entry in each line has the same value which is notated by An. The main aim of this paper is to find the general form of the matrix trace An powered positive integer m. To prove whether the general form of the matrix trace of An powered positive integer can be confirmed, mathematics induction and direct proof are used.
Distance and Areas Weighting of GWR Kriging for Stunting Cases In East Java
Authors: Ardianti Deby , Pramoedyo Henny , Nurjannah Nurjannah 
Published: May 2021

Spatial heterogeneity shows the characteristic location from one location to others location and it is the main assumption in Geographically Weighted Regression. The location becomes a weight on GWR model, There are two groups of location weight namely based on distance and area. The weight considers the closeness between the location. The accuracy weighted is needed because the weighting represents the data location. The aim of this research was to get a suitable weighting method for stunting data. This research used secondary data about stunting and the influence factors of stunting such as coverage visiting of pregnant women (K1), consumption of FE tablet, exclusive of breastfeeding, immunization coverage, and clean health behaviour. Those data obtained from the Healthy Ministry of East Jawa.Based on the results of this research show that the goodness weighting for GWR modell is Adaptive Bisquare Kernel (distance weighting). The predicted mapping stunting is showed by interpolation Kriging with a range of 27% to 49,5%.
Dynamical of Ratio-Dependent Eco-epidemical Model with Prey Refuge
Authors: Firdiansyah Adin Lazuardy 
Published: May 2021

This paper discusses the dynamic analysis of three species in the eco-epidemiology model by considering the ratio-dependent function and prey refuge. The prey refuge is applied under the fact that infected prey has protection instincts that allow it to reduce predation risk. Here, we get the boundedness and three equilibrium points where are existence under certain conditions. In the model, three equilibrium points are locally asymptotically stable and one of the equilibrium points is globally asymptotically stable. We find that the system undergoes Hopf bifurcation around the interior equilibrium point by choosing as a bifurcation parameter. We also find a condition for uniform persistence. Finally, several simulations of numerical are performed not only to illustrate the analytical results but also to illustrate the effect of the prey refuge.
Movimentos sociais, controle social repressivo e criminalização no Rio de Janeiro / Social movements, repressive social control and criminalization in Rio de Janeiro
Authors: Sanches Taísa , Almeida Brena , Paiva Angela 
Published: May 2021

A criminalização dos movimentos sociais no Brasil tem sido acirrada nos últimos anos, marcados pela adoção de um modelo de controle social repressivo direcionado às populações faveladas. Este artigo propõe que dita criminalização se remete especificamente aos símbolos e identidades relacionados à população pobre, notadamente na cidade do Rio de Janeiro. A partir da categoria “urbanismo subalterno” proposta por Ananya Roy, explora-se como os movimentos sociais favelados operaram transformações em seu repertório de ação, de forma a contestar dita criminalização. Apresentamos resultados e interpretações derivadas de pesquisas, realizadas entre 2013 e 2020, que acompanharam movimentos de mães e familiares de vítimas de violência estatal e movimentos em luta por moradia. AbstractThe criminalization of social movements in Brazil has been rampant in recent years, marked by the adoption of a model of repressive social control directed at favela’s populations. This article proposes that this criminalization targets specifically symbols and identities related to the poor population, notably in the city of Rio de Janeiro. Based on the category “subaltern urbanism” proposed by Ananya Roy, we explored how the favela’s social movements transformed their repertoire of action in order to contest this criminalization. We present results and interpretations derived from research carried out between 2013 and 2020, which followed movements of mothers and family members of victims of state violence, as well as movements in the struggle for housing.
Nutritional Risk Screening in Malignant Tumors: A Study of 375 Cancer Inpatients
Authors: Zhang Min , Guo Yuying , Zhang Xiaodi , Zhang Yu , Fan Yuanyuan , Liu Yanting , Zhao Kelei , Fan Ruijuan , Lu Ping 
Published: June 2021

Abstract
Different degrees of malnutrition are one of the most common complications in patients with malignant tumors, which often accelerate the progression of the disease and affect the therapeutic effect and prognosis of the disease. Therefore, in the early census of patients with malignant tumor, screening the possible nutritional risks and correcting the possible causes of various malnutrition are important measures to improve the quality of life of patients. Our study randomly included 375 patients diagnosed with malignant tumor in Henan province, and analyzed the relationship between nutritional risk and indicators include age, BMI, serum albumin, serum prealbumin, serum hemoglobin, tumor stage, tumor type, and inflammatory factors. we found that age, BMI, hemoglobin, and whether suffering from gastrointestinal tumors were the independent risk factors for nutritional risk in patients. We also found an significant correlation between inflammatory factors (IL-6 and IL-8) and nutritional risk status of cancer patients，so as to provide new prediction indexes for clinical management of nutritional risk and dynamic changes of nutritional status.
Safety and Efficacy of Hydroxychloroquine for Treatment of Non-Severe COVID-19 in Adults in Uganda: A Randomized Open Label Phase II Clinical Trial
Authors: Byakika-Kibwika Pauline , Sekaggya-Wiltshire Christine , Semakula Jerome Roy , Nakibuuka Jane , Musaazi Joseph , Kayima James , Sendagire Cornelius , Meya David , Kirenga Bruce , Nanzigu Sarah , Kwizera Arthur , Nakwagala Fred , Kisuule Ivan , Wayengera Misaki , Mwebesa Henry G , Kamya Moses , Bazeyo William 
Published: June 2021

Abstract
BackgroundSeveral repurposed drugs such as hydroxychloroquine (HCQ) have been investigated for treatment of COVID-19, but none was confirmed to be efficacious. While in vitro studies have demonstrated antiviral properties of HCQ, data from clinical trials were conflicting regarding its benefit for COVID-19 treatment. Drugs that limit viral replication may be beneficial in the earlier course of the disease thus slowing progression to severe and critical illness. DesignWe conducted a randomized open label Phase II clinical trial from October -December 2020.MethodsPatients diagnosed with COVID-19 using RT-PCR were included in the study if they were 18 years and above and had a diagnosis of COVID-19 made in the last 3 days. Patients were randomized in blocks, to receive either HCQ 400mg twice a day for the first day followed by 200mg twice daily for the next 4 days plus standard of care (SOC) treatment or SOC treatment alone. SARS COV-2 viral load using nasal/orapharyngeal swabs was performed at baseline, day 2, 4, 6, 8 and 10. The primary outcome was median time from randomization to SARS COV-2 viral clearance by day 6.ResultsOf the 105 participants enrolled, 55 were assigned to the intervention group (HCQ plus SOC) and 50 to the control group (SOC only). Baseline characteristics were similar across treatment arms. Viral clearance did not differ by treatment arm, 20 and 19 participants respectively had SARS COV-2 viral load clearance by day 6 with no significant difference, median (IQR) number of days to viral load clearance between the two groups was 4(3-4) vs 4(2-4): p=0.457. There were no significant differences in secondary outcomes (symptom resolution and adverse events) between the intervention group and the control group. There were no significant differences in specific adverse events such as elevated alkaline phosphatase, prolonged QTc interval on ECG, among patients in the intervention group as compared to the control group.ConclusionOur results show that HCQ 400mg twice a day for the first day followed by 200mg twice daily for the next 4 days was safe but not associated with reduction in viral clearance or symptom resolution. Trial registration: NCT04860284
Syphilis in Pregnant Women and Congenital Syphilis: Spatio-temporal Dynamics and Covariates in the Middle-income Country – São Paulo, Brazil
Authors: Ruberti Joelma Alexandra , Yamamura Mellina , Silva Zilda Pereira da , Domingues Carmen Silvia Bruniera , Waldman Eliseu Alves , Neto Francisco Chiaravalloti 
Published: June 2021

Abstract
We aimed to estimate the occurrence of syphilis in pregnant women (SPW) and congenital syphilis (CS) in the municipalities of the state of São Paulo (SP) and evaluate their relationship with socioeconomic, demographic, and health care variables. We developed an ecological study based on secondary data of SPW and CS with spatial and temporal components from 645 municipalities in SP and included data from 2007 to 2018. We modeled the data in a Bayesian context, considered spatial and temporal random effects, and used a binomial negative probability distribution. We found a continuous increase in the relative temporal risk of SPW, from 2007 to 2018, and CS, from 2007 to 2017, when their incidences increased by 8.7 and 6.6 times, respectively. Moreover, this increase occurred in en bloc in practically all municipalities of SP. The increase in SPW was associated with teenage pregnancy, municipalities with a large number of inhabitants, and aids incidence. The increase in CS was associated with municipalities with a large number of inhabitants, incomplete antenatal care, inadequate technology to perform deliveries in the municipality, and aids incidence. Interventions to control these diseases are needed in almost all the municipalities of the SP.
An Innovative Method for the Sustainable Utilization of Blast-furnace Slag in the Cleaner Production of One-part Hybrid Cement
Authors: Fayed Esraa K. , El-Hosiny Fouad I. , El-Kattan Ibrahim M. , Abdel-Gawwad Hamdy A. 
Published: June 2021

Abstract
Hybrid cement (HC) can be defined as alkali activated-blended-Portland cement (PC). It was prepared by the addition of an alkaline solution to high-volume aluminosilicate-blended-PC. Although this cement exhibits higher mechanical performance compared to conventional blended one (aluminosilicate-PC blend), it represents lower commercial viability because of the corrosive nature of an alkaline solution. Therefore, this study focuses on the preparing one-part-HC using dry activator-based blast-furnace slag (DAS). DAS was prepared by mixing sodium hydroxide (NaOH) with blast-furnace slag (BFS) at low water to BFS ratio, followed by drying and grinding to yield DAS-powder. Different contents of DAS (equivalent to 70 wt.% BFS and 1, 2, and 3 wt.% NaOH) were blended with 30 wt.% PC. A mixture containing 70 wt.% BFS and 30 wt.% PC was used as a reference sample. The mortar was adjusted at sand: powder (BFS-PC and/or DAS-PC) weight ratio of 3: 1. The microstructural analysis proved that DAS-powder is mainly composed of sodium calcium aluminosilicate activated species and unreacted BFS. These species can interact again with water to form calcium aluminum silicate hydrate (C-A-S-H) and NaOH, suggesting that the DAS acts as NaOH-carrier. One-part HC-mortars having 1, 2, and 3 wt.% NaOH recorded 7-days compressive strength values 82, 44, and 27 %, respectively, higher than that of the control sample. At 180-days of curing, a significant reduction in compressive strength was observed within HC-mortar having 3 wt.% NaOH. This could be attributed to the increase of Ca (within C-S-H) replacement by Na, forming Na-rich-phase with lower binding capacity. The main hydration products within HC are C-S-H, C-A-S-H, and chabazite as one of zeolite family.
A Case of Dystonic Storm: Storm That Was Mastered
Authors: Soni Lt Col (Dr) Rahul , Gupta Air Cdre (Dr) Salil , Dhull Col (Dr) Pawan , Srid Air Cdre (Dr) Madakasira Siraram 
Published: June 2021

Abstract
Background: Hyperkinetic movement disorder characterized by involuntary sustained or intermittent muscle contractions causing repetitive twisting movement, abnormal postures, or both is called dystonia. Its extreme severity is called ‘Dystonic Storm’, which is a life-threatening medical emergency. This is the only case that was managed with two surgical interventions, the Intrathecal Baclofen pump followed by Deep Brain Stimulation to Globus Pallidus Interna in addition to medical managementCase presentation: 16 years old boy, presented with insidious onset gradually progressive dystonia. Initially, he developed in lower limbs than in both upper limbs and the cervical region at the age of 08 years. His dystonia of the neck, arms, and trunk increased, walking became a problem, and even sitting became difficult over 24 hours. Dystonia movement continued even during sleep associated with dysautonomia. On investigation, his Creatine Phosphokinase was raised with 1324 IU/I. Bilirubin was normal but, liver enzymes were mildly raised. Urine for myoglobulin was negative, MRI was normal. He was managed as a case of dystonic storm injectable Vecuronioum infusion and Midazolam infusion. However, even then dystonia continued. Since dystonia was refractory to supportive and specific medical management, two-step procedures were planned to control the refractory dystonic storm. The first step was an Intrathecal Baclofen Pump as bridge therapy and then Deep Brain Stimulation to Globus Pallidus Interna was done. As part of an etiological investigation, his Clinical exome sequencing showed the CACNA1E gene, autosomal dominant (heterozygous) missense mutation on chromosome 1. Pathogenic CACNA1E variants presented with variable Developmental and Epileptic Encephalopathies characterized by movement disorders including dystonia in 60% cases. Conclusion: Status dystonicus is a rarest and life–threatening movement disorder emergency that requires both medical management (supportive and directive to precipitating factor and dystonia) and surgical intervention in a stepwise manner. Appropriate time of surgical intervention is key in management of dystonic storm.
Development of Highly Specific and Selectively Recognizing Caffeine
Imprinted Polymer Nanomaterials with EGDMA Crosslinker
Authors: Malik Babita , Suravajhala Renuka , Burri Harshavardhan Reddy 
Published: June 2021

Background:
Molecular imprinting approach involves a two-step process, template-functional
monomer complex and co-polymerization process. The loose polymer networks are known
to have limitations towards binding cavities with low specificity and cavity shrinking after template
removal lead to inefficient template-based imprinted polymer networks. To overcome optimization
of crosslinkers and FMs concentration lead to efficient organic imprinted polymer networks.

Methods:
The present study focused on selective recognition of caffeine specific cavities in the
Molecular Imprinted Polymer (MIP) networks. The degree of crosslinking was optimized based on
the template to study the rebinding capacity.

Results:
A self-assembled co-polymerization with functional monomers (FM) as methyl acrylamide
(MAA), ethylene glycol dimethyl acrylate (EDMA) / cross-linker in 1:20,40:60 ratio of
FM:crosslinker leads to caffeine with/without networks in imprinted polymers. Furthermore, The
synthesized imprinted nano polymers were characterized by UV-VIS, FTIR, GC-MS ,SEM spectral
analysis.

Conclusion:
We have observed that 30-50 nm particle size in MIPs and 60-92 nm particle sizes in
NIPs The specific selective binding of caffeine and its analogues as hydrazone, naphthalene and hypoxanthine
were investigated.It was proved from rebinding studies that in imprinted nanomaterials
polymers with 1:10 :20, 40, 60 (template: FM: crosslinker) had 62-70% maximum specific selectivity.
PLC-based lumber humidity measurement method
Authors: Nguyen V. V. , Shilin A. A. , Momot P. M. 
Published: May 2021

Purpose or research.The paper considers the solution of the scientific and practical problem of measuring the humidity content of lumber on the basis of a programmable logic controller (PLC), which makes it possible to implement control systems for drying lumber on inexpensive controllers of wide application with the advantages of modern SCADA systems.Methods.To achieve this goal, modern methods for assessing the humidity content of lumber by electrical resistance have been investigated. We have provided a review and analysis of the known dependences of the electrical resistance of lumber on moisture. It is noted the need to measure resistance in the range of 2.5 KΩ to 25 MΩ. The schematic solution for matching a high-resistance measurement bridge with an additional voltage source with a PLC is described here. We have proposed a method for calculating the matching scheme. Expressions are obtained for calculating humidity according to the data of an analog-to-digital converter. The procedure for setting up the measurement channel according to the readings of two reference measurements is presented.Results.The estimation of the measurement error of humidity and resistance is carried out. It is shown that a resistance measurement error of up to 20% leads to a humidity measurement error of up to 1%, provided that the parameters are correctly configured. To set it up, it is enough to take two reference measurements to complete the procedure for setting the humidity measurement parameters.Conclusion.In the process of designing modern systems for drying lumber, you can use the algorithms and programs of the technological process available and well presented in the literature for implementation on the PLC. The article offers a solution to the main problem of measuring the humidity content of lumber, which is necessary for these algorithms and programs. The material can be useful for researching technological stages of the drying process and developing industrial control systems based on inexpensive controllers.