bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identification of satellited markers by microdissection and fluorescence in situ hybridization: a clinical case of isodicentric chromosome 22
Authors: Lemskaya Natalya A. , Romanenko Svetlana A. , Maksimova Yulia V. , Shorina Asia R. , Yudkin Dmitry V. 
Published: April 2021

Abstract
Background
The presence of small supernumerary marker chromosomes (sSMCs) in a karyotype leads to diagnostic questions because the resulting extra material may cause abnormal development depending on the origin of the duplication/triplication. Because SMCs are so small, their origin cannot be determined by conventional cytogenetic techniques, and new molecular cytogenetic methods are necessary. Here, we applied a target approach to chromosome rearrangement analysis by isolating a chromosome of interest via microdissection and using it in fluorescence in situ hybridization (FISH) as a probe in combination with whole-chromosome painting probes. This approach allows to identify origins of both the euchromatin and repeat-rich regions of a marker.

Case presentation
We report a case of an adult male with congenital atresia of the rectum and anus, anotia, and atresia of the external auditory canal along with hearing loss. Karyotyping and FISH analysis with whole-chromosome painting probes of acrocentric chromosomes and the constructed microdissection library of the marker chromosome reliably identified an additional chromosome in some metaphases: mos 47,XY,+idic(22)(q11.2)[14]/46,XY [23].

Conclusion
We propose to use whole-chromosome libraries and microdissected chromosomes in FISH to identify SMCs enriched with repeated sequences. We show that the methodology is successful in identifying the composition of a satellited marker chromosome.
Management of constipation in patients with schizophrenia—a case study and review of literature
Authors: Sarangi Ashish , Armin Sabiha , Vargas Aurelio , Chu Victoria M. , Fain Kristen , Nelson Jessica 
Published: April 2021

AbstractBackgroundSchizophrenia is a disorder that affects about 1% of the US population, with an extensive impact on patients’ health and their risk of later developing comorbidities from treatment. While literature on the side effect profile of antipsychotics is abundant, there are few studies on identification of anticholinergic effects on gut motility and prophylaxis development. The aim of this review is to consider antipsychotic-associated constipation in patients with schizophrenia and to discuss management of antipsychotic-induced constipation as documented in the literature.Main bodyWe present a case of antipsychotic-induced constipation and conducted a literature review assessing the prevalence of this issue in this population. The search was done on Embase, MEDLINE, Cochrane Library, and PubMed databases. Key word searches included constipation with concurrent antipsychotic use, antipsychotics and anticholinergic effects, factors causing constipation in schizophrenia, social disparities involved with constipation, and colorectal cancer screenings.Main findings included high complication rates that may be explained by clozapine-specific side effects, negative health habits, disease, and treatment-related metabolic disorders. Co-existing negative symptoms could also be associated with health outcomes and was found to have adverse consequences on schizophrenia progression. Comorbidities of diabetes and cardiovascular complications contributed to gut hypomotility. Caregiver burden was a factor in delayed recognition of constipation as a side effect. Routine surveillance for symptoms and optimization of medications facilitates early recognition of constipation.ConclusionOverall, there is insufficient trial-based evidence to compare the effectiveness and safety of common pharmacological interventions for constipation, such as lactulose, polyethylene glycol, stool softeners, and lubricant laxatives.
Cord levels of zinc and copper in relation to maternal serum levels in different gestational ages
Authors: Abdellatif May , Elhawary Ismail Mohamed , Mahmoud Marwa Mohamed , Youness Eman R. , Abuelhamd Walaa Alsharany 
Published: April 2021

Abstract
Background
A few published data on maternal and cord levels of zinc and copper with conflicting results were reported. We aimed to measure zinc and copper levels in the maternal blood and cord blood of newborns and correlate their levels with the gestational age and anthropometric measurements. This cross-sectional study included 75 full-term and preterm neonates and their mothers. These neonates were divided into 2 groups according to their gestational age. Serum levels of copper and zinc were estimated for the mothers of the studied neonates as well as their cord samples. This was done using atomic absorption spectrophotometry.

Results
The mean cord serum zinc in full term was 0.88 ± 0.18 μg/ml whereas in preterms was 0.73 ± 0.13 μg/ml. The mean cord copper in full term was 1.37 ± 0.26 μg/ml, whereas in preterms was 0.75 ± 0.28 μg/ml. Comparison between cord zinc and copper levels and maternal levels were statistically significant (p < 0.001). A significant positive correlation was found between zinc levels in neonates and their mothers (r 0.644; p < 0.000) and a similar positive correlation was found between copper levels in neonates and their mothers (r 0.625; p 0.000). A highly significant positive correlation was found between cord zinc and copper and anthropometric measurements.

Conclusion
The present work draws our attention to the significant correlation between trace elements in pregnant mothers and fetal development. Also, prematurity adversely influences zinc and copper levels in neonates.
Reduction of intussusception under general anesthesia by hydrostatic technique: the RIGHT technique
Authors: Chand Karunesh , Patcharu Ravi , Parikh Badal , Yadav Arun Kumar 
Published: April 2021

Abstract
Background
Intussusception is the one of the commonest causes of intestinal obstruction requiring urgent attention in early childhood. There is no gold standard of non-operative reduction. We report our 6 years’ experience in non-operative reduction using our “RIGHT” (Reduction of Intussusception under General anesthesia using Hydrostatic Technique) technique, emphasizing the need to perform the procedure in the operating room (OR) under general anesthesia. This prospective observational study covering the period from July 2014 till May 2020 included patients diagnosed with intussusception. Hydrostatic reduction was performed in the OR under general anesthesia by infusing a saline enema and the reduction was confirmed by ultrasound.

Results
Forty-eight patients underwent reduction using the RIGHT technique. Successful reduction was achieved in 44 (91.6%) patients. Four (8.3%) patients needed surgery, three (6.2%) due to failed reduction and one (2.0%) due to perforation. One (2.2%) patient developed a recurrence.

Conclusions
The “RIGHT” technique is a combination of the best available techniques of reduction of intussusception. It ensures patient safety by being performed in the OR, being pain free, avoiding radiation, avoiding the risk of aspiration associated with sedation, and also being able to immediately address a failure of reduction or a complication by surgical exploration.
ФОРМИРОВАНИЕ ПРОФЕССИОНАЛЬНОЙ ИДЕНТИЧНОСТИ СТУДЕНТОВ 1 КУРСА КОЛЛЕДЖА
Authors: Baryshnikova Ekaterina Leonidovna 
Published: April 2021

Цель. Статья посвящена актуальной в современном обществе теме профессиональной идентичности и средствам ее формирования в процессе обучения профессии. В статье приведены промежуточные результаты педагогического эксперимента, проводимого в рамках исследования формирования профессиональной идентичности обучающихся в системе среднего профессионального образования посредством гендерного подхода.Метод или методология проведения работы. Основу исследования образуют теоретические методы: изучение и анализ научно-методической литературы по исследуемой проблеме, анализ, педагогическое прогнозирование и моделирование; и эмпирические методы: наблюдение; тестирование; контент-анализ; методы математической статистики.Результаты. Результаты работы заключаются в том, что автор наблюдает положительную динамику в исследуемых параметрах оценки сформированности профессиональной идентичности учащихся экспериментальных групп, в частности параметров «номинал профессии» и «соотношении профессии с собой». Автор делает предположение, что положительный результат был достигнут благодаря педагогическому воздействию согласно разработанной методике.Область применения результатов. Результаты исследования могут быть применены в системе среднего профессионального образования.
ЯЗЫКОВЫЕ ПРЕДСТАВЛЕНИЯ КАК ФОРМА СОЦИАЛЬНОГО ЗНАНИЯ
Authors: Razumova Lina Vasilyevna 
Published: April 2021

Цель. Статья посвящена уточнению характера языковых знаний в системе социального знания. Социальное представление (репрезентация) – сложная когнитивная структура. Как социальная форма знания социальное представление служит для интерпретации социальной действительности. Оно позволяет понять и подвергнуть анализу регулирующее действие социальной системы на когнитивную область социальной группы, индивида. Автор ставит целью уточнить основные характеристики языкового представления (языковой репрезентации) и его структуру как формы социального знания. Актуальность статьи определяется, с одной стороны, возросшим интересом к когнитивным разработкам, способных раскрыть сложные механизмы категоризации человеческих знаний. С другой стороны, речь идет о попытке автора применить психологическое понятие представления для уточнения психосоциальных характеристик языковых знаний, в частности – представлений о языковой норме как одной из форм социального знания.Научная новизна исследования заключается в соотнесении социально-психологической и языковой основ языковой репрезентации.Теоретическая и практическая значимость работы состоит в комплексном анализе взаимодействия социальной среды, функциональной системы языка с его внутренней структурой на примере изучения репрезентации языковой нормы бельгийского и квебекского вариантов французского языка.Материалом для исследования послужили языковые представления носителей языка о языковой норме территориальных вариантах французского языка Бельгии и Квебека, представленных в бельгийских и французских грамматиках XVI–XIX вв., квебекских лексикографических работах XVIII – начала XX столетий, в исторических свидетельствах о языке.Результаты исследования. Инструментарий социальной психологии, основной единицей которой выступает социальная репрезентация, позволил существенно расширить представление о норме как сложной когнитивной структуре, опирающейся не только на разрабатываемое в обществе научное знание, но и на знание естественное, опытное, которому свойственно неограниченное число инференций, следований, что позволяет установить неограниченное число связей между наблюдаемыми предметами. Соединение научного и опытного знания, социального и индивидуального определяют амбивалентный, рационально-оценочный, с одной стороны, и социально-индивидуальный характер нормы, с другой. Языковая норма как один из типов социальной нормы формируется в процессе взаимодействия нескольких социальных групп, определяющих свое отношение, в том числе и идентификационное, к языку (языковой форме).
Puppets, Gods, and Brands: Theorizing the Age of Animation from Taiwan, 1st ed., Teri Silvio (2019)
Authors: Yee Jared 
Published: April 2021

Review of: Puppets, Gods, and Brands: Theorizing the Age of Animation from Taiwan, 1st ed., Teri Silvio (2019)
Honolulu: Hawaii University Press, 290 pp.,
ISBN-13 978-0-82487-662-3, h/bk, $80
ISBN-13 978-0-82488-116-0, p/bk, $30
Picture Pedagogy: Visual Culture Concepts to Enhance the Curriculum, Paul Duncum (2020)
Authors: Gil-Glazer Ya’ara 
Published: April 2021

Review of: Picture Pedagogy: Visual Culture Concepts to Enhance the Curriculum, Paul Duncum (2020)
London and New York: Bloomsbury Academic, 225 pp.,
ISBN 978-1-35014-464-4, p/bk, £22.99
Re-imagining the Art School: Paragogy and Artistic Learning, Neil Mullholland (2019)
Authors: Pybus Christine 
Published: April 2021

Review of: Re-imagining the Art School: Paragogy and Artistic Learning, Neil Mullholland (2019)
Cham: Palgrave Pivot, 145 pp.,
ISBN 978-3-030-20628-4, h/bk, €51,99
ISBN 978-3-030-20629-1, e-book, €42,79
Mirror reflections in sport: A compilation study
Authors: Ceylan Gizem , Tuncel Semiyha 
Published: April 2021

Mirrors in sports halls have changed from an accessory view to an educational material view for the individual who teaches and learns physical activities (dance, boxing, pilates, zumba, gymnastics, etc.) in which visual learning is predominant. In this context, the aim of our research is to examine the studies carried out on 'mirrors in sports' in the field of sports, and to find out what kind of effect the educational environment is mirrored on teaching, learning and psycho-social processes of individuals. In the study, in which the thematic review design was used, a detailed literature review was made, and the research data were obtained by examining the resources from journals, books, theses and papers within the scope of Google Scholar, Pubmed and Yöktez. Document analysis method was used in the analysis of the data obtained. As a result, the achievable national and international studies on mirrors; mirrors provide an advantage in skill learning for the individual who provides education and training during learning, but in the process of learning, especially in professional athletes, if the use of mirrors continues, proprioception (deep sensation) and kinesthesia (joint position awareness) may cause regression and in individual sports branches where visual learning method is used and It has also been observed that the use of mirrors in physical activities involving group exercises may have negative psycho-social effects for beginner athletes or sedentary individuals.

Özet

Spor salonlarında ki aynalar genelde görsel öğrenmenin ağırlıklı olduğu fiziksel aktiviteler de (dans, boks, pilates, zumba, jimnastik vb.) öğreten ve öğrenen birey açısından aksesuar görünümünden eğitim materyali görünümüne geçmiştir. Bu bağlamda spor alanın da ‘spor da aynalarla’ ilgili yapılmış olan çalışmaları inceleyerek, eğitim ortamının aynalı olması durumunun öğretim, öğrenme ve bireylerin psiko-sosyal süreçlerine ne gibi bir etkisi olduğuna ulaşmak araştırmamızın amacını oluşturmaktadır. Tematik derleme deseninin kullanıldığı çalışmada, alanyazına dayalı detaylı kaynak taraması yapılmış, araştırma verileri Google Akademik, Pubmed ve Yöktez kapsamında, dergi, kitap, tez ve bildirilerden konuya ilişkin kaynaklar incelenerek elde edilmiştir. Ulaşılan verilerin analizinde döküman analizi yöntemi kullanılmıştır. Sonuç olarak aynalarla ilgili ulaşılabilinen ulusal ve uluslararası çalışmaların; aynaların öğrenme esnasında eğitim veren ve eğitim alan birey açısından beceri öğreniminde bir avantaj sağladığı ancak öğrenme sonrasındaki süreçte özellikle profesyonel sporcularda ayna kullanımının sürekliliği halinde propriyosepsiyon (derin duyum) ile kinesteziyi (eklem poziyon farkındalığı) gerilemeye neden olabileceği ve görerek öğrenme yönteminin kullanıldığı bireysel spor dallarında ve grup egzersizlerinin söz konusu olduğu fiziksel aktivitelerde ayna kullanımının başlangıç düzeyindeki sporcular ya da sedanter bireyler için psiko-sosyal açıdan olumsuz etkilere neden olabileceği de gözlemlenmiştir.
Effects of a 16-Week Multimodal Exercise Program on Physical Performance in Individuals With Dementia: A Multicenter Randomized Controlled Trial
Authors: Barisch-Fritz Bettina , Trautwein Sandra , Scharpf Andrea , Krell-Roesch Janina , Woll Alexander 
Published: April 2021

Background and Purpose:
Dementia affects physical as well as cognitive performance. In individuals with dementia (IWD), decline in physical performance increases with disease progression and is associated with higher functional dependence and decreased quality of life. It is paramount to examine factors that potentially preserve physical performance in IWD, particularly in light of conflicting findings on the effectiveness of physical activity interventions on physical performance of IWD, mainly due to limited number of high-quality studies, large heterogeneity in methods used, or insufficient reporting of methods. The aim of this study was to investigate the effects of a 16-week multimodal exercise program (MEP) combining physical and cognitive tasks on physical performance in IWD, and to identify individual characteristics of MEP responders.

Methods:
A multicenter randomized controlled trial with assessment methods identified by an expert panel was conducted. We included 319 IWD of mild to moderate severity, older than 65 years, who underwent a standardized MEP specifically designed for IWD. At baseline and immediately after the MEP, we assessed physical performance (ie, mobility, balance, and strength) and function of lower extremities (primary outcomes). Potential effects of the MEP on physical performance were identified using 2-factor analyses of variance with repeated measurements within 2 samples (ie, intention-to-treat and per-protocol sample). Additionally, we compared characteristics related to physical performance between positive, non-, and negative responders.

Results and Discussion:
Neither analysis procedure revealed statistically significant time×group effects. However, 28% to 40% of participants were positive responders with regard to balance, and strength and function of lower extremities; and these persons had statistically significant lower baseline performance in the corresponding assessments.

Conclusions:
This randomized controlled trial revealed no overall effects of the MEP on physical performance, probably due to high heterogeneity of the study sample. Findings in responder analysis showed that IWD with lower physical performance at baseline tended to benefit more than those with higher baseline performance. Thus, a higher degree of individualization of the MEP depending on baseline performance on IWD may improve overall MEP effectiveness.
Strength and Conditioning for Cricket Spin Bowlers
Authors: Mathankar Apurva , S Kirti 
Published: April 2021

ABSTRACT
Although the popularity of cricket is increasing, there is a lack of strength and conditioning research into position-specific roles. Much of the available research on cricket spin bowling is based on ball swing, flight, deviation, and its principles. Less is known about the demands of the cricket spin bowler (needs analysis) and the specific training methods needed for the optimal performance of the athlete. Spin bowlers are considered to play a crucial role in bowling attacks against the batting team. The batsman is deceived by the spin bowler by adding revolutions to the ball and thus deviates it off the wicket. Therefore, to improve the cricket team's performance, it is prudent to focus on improving the performance of the team's spin bowlers. needs analysis based on a review of literature in the area of biomechanics, time-motion analysis, physiology, and injury epidemiology specific to cricket spin bowlers is provided in this article. Based on these analyses, practical considerations and guidelines for the implementation of strength and conditioning programs for the spin bowlers are provided.
UNDERSTANDING MENTAL HEALTH IN MALAYSIAN ELITE SPORTS: A QUALITATIVE APPROACH
Authors: Lew Philip Chun Foong , Wong Rebecca Sook Kwan 
Published: April 2021

The attention in the society and rapid expansion of interest on the status and challenges of mental health among sporting athletes, especially in the elite sports setting, had increased exponentially. The present study was aimed to explore and gain a better understanding of mental health and psychological well-being of Malaysian elite athletes. It also provides insights into a broader aspect based on participants’ personal experiences. A semi-structured interview was conducted for all 32 athletes (male, n=16; female, n=16) from a variety of sport: individual, team-sports; able-bodied, and Paralympic. Participants were aged between 19-38 years old (mean 25.69 years) from various ethnicity and religions. Six (6) themes (Personal understanding on mental health; Stigma of mental health; Symptoms, effects and sources of mental health; Coping strategies; Mental health and well-being support; Advice of athletes) and 19 subthemes were derived based on qualitative thematic analysis. Based on the analysis, subthemes, i.e. Presentation in mass media; Transition; Personal life-related issues; Performance expectation; Sporting environment are significant stressors causing mental health issues. The influence of spirituality and religion on the topic of mental health was also being highlighted. In conclusion, it is hopeful that the present study will stimulate interest and discussion in identifying methods and direction for both researchers and practitioners in bridging the theoretical-applied gap and offer effective supports to Malaysian athletes.
Postpartum clinical evaluation of omission of bladder flap during cesarean section
Authors: UZUN Asiye , AYDIN Emrah , ERSAN Fatma , ELÇİ ATILGAN Adeviye , LEYLA ALTUNTAŞ Şükriye 
Published: April 2021

Objective: Cesarean section (C/S) is one of the most common operation performed by the gynecologist throughout the world. The aim of this study is to present our experience in this particular group of patients and compare the early and late outcomes of the patients with and without a bladder flap after a C/S procedure.
Materials and Method: All cases admitted between October 2018 and January 2019 due to C/S were retrieved from hospital electronic medical records. Data were collected on demographics, perioperative test results, operative characteristics, postoperative complications and outcomes. The C/S decision was given by the surgeon per fetal or maternal problems such as placenta previa, ablatio placenta, malpresentation, fetal distress, macrosomia and prolapses of the umbilical cord. Patients were grouped into two as Group 1 comprised patients who had C/S with bladder flap while Group 2 included the patients without bladder flap.
Results: There were 63 patients included in the study with a mean age of 27.87 ± 4. None of the patients in either group had bladder injury. The comparison of the groups demonstrated the group were statistically equal in maternal age, weight, body mass index (BMI) and gestational week. The presence of microhematuria was significantly higher in Group 1 patients (p=0.000, OR 2.55, 95% CI 1.568-4.159) and there was statistically significant decrease in the hemoglobin levels (Group 1 0.91 ± 1.48 vs Group 2 0.13 ± 1.24, p=0.026). However, the decrease in the hematocrit values did not statistical significance (Group 1 1.78 ± 6.84 vs Group 2 0.63 ± 4.09, p=0.423). The postoperative residual urine, on the other hand, was slightly higher in patients with bladder flap.
Conclusion: Bladder flap during C/S has adverse effects on the blood loss, surgical time and postoperative symptoms. Hence, omitting the flap will improve the postoperative comfort both for the patient and the surgeon.