bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Central Engines of Fermi Blazars
Authors: Paliya Vaidehi S. , Domínguez A. , Ajello M. , Olmo-García A. , Hartmann D. 
Published: March 2021

Abstract
We present a catalog of central engine properties, i.e., black hole mass (M
BH) and accretion luminosity (L
disk), for a sample of 1077 blazars detected with the Fermi Large Area Telescope. This includes broad emission-line systems and blazars whose optical spectra lack emission lines but are dominated by the absorption features arising from the host galaxy. The average M
BH for the sample is

, and there is evidence suggesting the association of more massive black holes with absorption-line systems. Our results indicate a bimodality of L
disk in Eddington units (L
disk/L
Edd) with broad-line objects tend to have a higher accretion rate (L
disk/L
Edd > 0.01). We have found that L
disk/L
Edd and Compton dominance (CD; the ratio of the inverse Compton to synchrotron peak luminosities) are positively correlated at the >5σ confidence level, suggesting that the latter can be used to reveal the state of accretion in blazars. Based on this result, we propose a CD-based classification scheme. Sources with CD > 1 can be classified as high-Compton-dominated or HCD blazars, whereas those with CD ≲ 1 are low-Compton-dominated (LCD) objects. This scheme is analogous to that based on the mass accretion rate proposed in the literature; however, it overcomes the limitation imposed by the difficulty in measuring L
disk and M
BH for objects with quasi-featureless spectra. We conclude that the overall physical properties of Fermi blazars are likely to be controlled by the accretion rate in Eddington units. The catalog is made public at http://www.ucm.es/blazars/engines and Zenodo.
Records and descriptions of caddisflies from Natma Taung National Park and adjacent localities in the Chin Hills of Myanmar (Insecta, Trichoptera)
Authors: Mey Wolfram , Malicky Hans 
Published: March 2021

During several excursions to the Chin Hills of Myanmar from 2001 to 2015, rich collections of caddisflies were made which form the basis of the present taxonomic and biogeographic study. A total of 106 species were identified including seven new species. They are described as Arctopsyche subflavasp. nov., Hydromanicus abdominalissp. nov., Cheumatopsyche janosolahisp. nov., Lepidostoma subpanaitossp. nov., Aplatyphylax pumilussp. nov., Adicella natmataungensissp. nov. and Triaenodes mindatensissp. nov.
Illustrations of the male genitalia and images of the adults are provided. Two species names were recognised as junior synonyms: Hydropsyche athamas Malicky &amp; Chantaramongkol, 2000, = Hydropsyche januha Oláh &amp; Barnard, 2008, syn. nov.; Hydropsyche khasigiri Oláh &amp; Barnard, 2008, = Hydropsyche kiogupa Oláh &amp; Schefter, 2008, syn. nov.
In an attempt to determine the biogeographic character of the fauna, the known ranges of all resident species were plotted into three longitudinal transects from 85°–95°E, 95–98°E and 98°–108°E, ranging from the eastern Himalayas to northern Vietnam. About half of the species have ranges extending over all three transects. The fauna is equally composed of western and eastern species qualifying the Chin Hills as part of a transition zone including palearctic elements. Most of the species, which are widely distributed in south-east Asia, are members of the suborder Annulipalpia. The investigations of the authors yielded 77 autochthonous species, which have been unrecorded from the country including the newly-described taxa. This brings the number of species records from Mynamar to 304.
Evaluation of Chemerin in Acute Coronary Syndrome and its Role in Cardiodiabetics
Authors: Kumar Manoj , Prajapati Rajpal , Saxena Piyush , Singh Anshul , Misra Vatsala 
Published: March 2021

Objectives:
Chemerin is a proinflammatory adipokine whose role in metabolic syndrome and insulin resistance is well known. Chemerin has shown to carry a good prognostic/predictive value in patients of Coronary Artery Diseases (both chronic as well as acute) in the studies done in the US and Europe. However, no such study has been reported from India. Hence, this study was undertaken to evaluate Chemerin in patients of Acute Coronary Syndrome (ACS) and assess their role in cardiodiabetic patients.

Materials and Methods:
We included seventy cases of ACS and further subdivided them into two groups - (1) with co-existing diabetes mellitus (ACS-DM) (n = 33) and (2) without co-existing DM (ACS-NDM) (n = 37). Thirty healthy age and sex matched controls were included for comparison. Chemerin levels were measured by ELISA, hs C Reactive Protein (hs CRP) by turbidimetric assay, Creatine Kinase MB (CK-MB) by immunoinhibition (IFCC method) and Troponin I (Trop I) by Chemiluminescent Microparticle immunoassay. All the data were analyzed using Social Science Statistics Calculators.

Results:
Serum Chemerin levels were highest in ACS-DM (0.80 ± 0.61 ng/ml) as compared to ACS-NDM (0.42 ± 0.22 ng/ml) and controls (0.25 ± 0.10 ng/ml). On comparison, the difference amongst all was statistically significant. Furthermore, Chemerin showed a positive correlation with all the three parameters of ACS – hs CRP, CK- MB and Trop I.

Conclusion:
Chemerin levels are markedly elevated in ACS patients, more so in those with coexisting diabetes [cardio diabetics]. Chemerin is a novel biomarker of ACS.
Health Professionals’ Stigma towards the Psychiatric Ill in Nigeria
Authors: Ubaka Chukwuemeka Michael , Chikezie Chioma Mirrian , Amorha Kosisochi Chinwendu , Ukwe Chinwe Victoria 
Published: March 2021

BACKGROUND: Stigma affects the quality of life of the mentallyill, and health professionals are considered to be involved in possessing negative attitudes towards them. We evaluated the prevalence of stigmatization among different health professionals in Nigerian hospitals.METHODS: This study was a descriptive, cross-sectional and comparative survey assessing attitudinal views of health professionals (doctors, pharmacists, and nurses) regarding mental illness in two hospitals in Eastern Nigeria. The survey utilized the 40-item Community Attitude to Mental Illness, CAMI-2 questionnaire. The prevalence and the factors that contribute to negative attitudes among this cohort were assessed. Statistical analysis using T-tests, ANOVA and Pearson Correlation were conducted.RESULTS: Attitudes to all the four constructs of the CAMI-2 werenon-stigmatizing. Stigmatizing attitudes were significantly higheramong pharmacists, doctors and then nurses (p<0.006). Health professionals who did not have contact with the mentally ill (p<0.0001), who were males (p=0.008) and had lower years of working experience (p=0.031) expressed significantly higher stigmatizing attitudes towards the mentally ill.Conclusions: Nigerian health professionals were largely non-stigmatizingtowards the mentally ill. However, being a pharmacist, of male gender, and working in a non-psychiatric hospital were associated with stigmatizing attitudes when they exist.KEYWORDS: Mental illness; Stigma; Health Professionals;Survey
Hubungan Pajanan Pestisida Dengan Efek Neurobehavioral Pada Petani Cabai Merah Di Kecamatan Beringin
Authors: Meirindany Tina , Indirawati Sri Malem , Marsaulina Irnawati 
Published: March 2021

Salah satu kegiatan dalam meningkatkan kualitas hasil pertanian tidak terlepas dari penggunaan pestisida. Penggunaan pestisida di Indonesia masih didominasi pestisida berbahan kimia. Usaha pertanian khususnya cabai merah masih menggunakan pestisida dari golongan organofosfat. Berbagai studi epideomiologi menunjukkan bahwa individu yang terpapar organofosfat secara akut dan kronik akan mengalami gangguan neurologis jangka panjang yang disebut efek neurobehavioral. Tujuan penelitian ini untuk menganalisis pajanan pestisida dengan efek neurobehavioral pada petani cabai merah di Kecamatan Beringin. Jenis penelitian ini adalah penelitian observasional analitik dengan desain cross sectional. Populasi penelitan adalah seluruh petani cabai merah yang tergabung dalam kelompok Juli Tani desa Sidodadi Ramunia. Sampel adalah 46 petani cabai merah. Pengumpulan data menggunakan kuisioner Q18 Versi Jerman yang dilajutkan dengan uji performa neurobehavioral menggunakan instrument digit symbol, digist span, pursuit aiming dan trail making. Hasil sebanyak 60,9% petani mengalami efek neurobehavioral tidak normal dan 39,1% petani mengalami efek neurobehavioral normal, berdasarkan analisis menunjukkan ada hubungan antara usia ( p = 0,003), masa kerja (p = 0,000), dan jenis pestisida (p = 0,013) dengan efek neurobehavioral pada petani cabai merah di Kecamatan Beringin. Kesimpulan usia, masa kerja petani, dan jenis pestisida dapat menyebabkan efek neurobehavioral tidak normal pada petani cabai merah di Kecamatan Beringin
Pengembangan Algoritma C4.5 Berbasis Particle Swarm Optimization untuk Penentuan Kelayakan Asuransi
Authors: Indriyanto Jatmiko , Huda Miftakhul , Afriliana Ida 
Published: March 2021

Tujuan penelitian ini adalah untuk Pengembangan Algoritma C4.5 Berbasis Particle Swarm Optimization Untuk Penentuan Kelayakan Asuransi. metode logistic regresion, decision trees, k-nearest neighbors, naïve bayes dan support vector machines. Model tersebut akan menentukan atau memprediksi status konsumen dimasa mendatang. Observasi yang mirip juga pernah dilakukan, tetapi dengan cara berbeda. Pada penilitian ini, akan digunakan algoritma klasifikasi C4.5 berbasis Particle Swarm Optimization (PSO), hasil ketepatan yang diinginkan lebih bagus dibandingkan hanya memakai algoritma C4.5 untuk mengatasi permasalahan pada kasus pemilihan produk asuransi. dapat disimpulkan bahwa nilai akurasi yang didapatkan pada model algoritma C4.5 berbasis PSO adalah 98.93% lebih bagus jika dibandingkan dengan model algoritma C4.5 yaitu 97.84%. Dari hasil tersebut didapatkan perbedaan antara kedua model yaitu senilai 0.4%. Selagi untuk penelaahan menggunakan ROC curve bagi kedua model ialah,untuk model algoritma C4.5 nilai AUC adalah 0.970 dengan urutan diagnosa Excellent Classification, dan untuk model algoritma C4.5 berbasis PSO nilai AUC adalah 0.968 dengan urutan diagnosa Excellent Classification.
The Effect of Current Ratio and Debt to Equity Ratio on Stock Prices with Return on Equity as an Intervening Variable in Food and Beverage Companies
Authors: Christia Christia , Nurmala Sari Eka , Noviyanti SimoranJkir Enda , Hutagalung Galumbang 
Published: March 2021

This study aims to test and analyze the effect of Current Ratio and Debt to Equity Ratio on stock prices with ROE as an intervening variable . This research is a quantitative research. The population of food and beverage companies is 23 companies using purposive sampling technique, so samples that meet the criteria for analysis are 13 companies. The data were analyzed using multiple linear regression analysis, the cc›efficient of determination, the F test, and the T test. The results showed that the Current Ratio had a positive and significant effect on ROE and stock prices. DER has a positive and significant effect on ROE but has a significant negative effect on stock prices and ROE has a positive and significant effect on stock prices. CR and DER have an indirect effect on stock prices through ROE.
Financial Reporting Quality and Investment Efficiency: Evidence from Indonesian Stock Market
Authors: Ardianto Hanif Putra , Harymawan Iman , Paramitasari Yuanita Intan , Nasih Mohammad 
Published: March 2021

This study aims to analyze the impact of financial reporting quality on the investment efficiency of a company. The study uses 994 observations from companies listed on the Indonesia Stock Exchange (IDX) in three periods from 2013 to 2015. The findings suggest that higher financial reporting quality has a positive and significant relationship with investment efficiency. Furthermore, the tests were conducted on groups of companies experiencing underinvestment and overinvestment. It was found that higher financial reporting quality had a negative and significant relationship with companies experiencing overinvestment. The findings provide implications for investors in assessing investment management carried out by company.
Association of the MMP-3, MMP-9 and MMP-12 gene polymorphisms with COPD risk: a meta-analysis
Authors: Zhao Hua , Jiang Xiao-Hong , Huang Qiu-Pin , Chen Min-Li , Xie Zheng-Fu 
Published: March 2021

IntroductionGiven the evidence that the matrix metalloproteinases (MMPs) play an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD), a number of case-control studies have attempted to assess the relationship between genetic polymorphisms in MMP genes and COPD risk. However, reliable measures of these results are lacking.Material and methodsWe assessed the published evidence for association of the MMP-3, MMP-9 and MMP-12 polymorphisms with COPD risk using meta-analytic techniques. The odds ratio (OR) and 95% confidence interval (CI) were calculated for each study using fixed or random effect models.ResultsA total of 23 case-control studies were included in the meta-analysis. No significant association was observed between the MMP-9 rs3918242 polymorphism and COPD risk in the overall populations under the dominant (T/T + C/T vs. C/C: OR = 1.30, 95% CI: 1.00–1.69, p = 0.054) and allele contrast (T allele vs. C allele: OR = 1.22, 95% CI: 0.97–1.53, p = 0.088) models. However, in sub-group analysis the polymorphism rs3918242 was significant in Asians under the dominant model (T/T + C/T vs. C/C: OR = 1.66, 95% CI: 1.02–2.72, p = 0.043). The results for MMP-12 rs2276109 showed an association with COPD only in mixed populations (G/G + A/G vs. A/A: OR = 1.57, 95% CI: 1.10–2.24, p = 0.013; G allele vs. A allele: OR = 1.52, 95% CI: 1.09–2.14, p = 0.015). We did not find any significant association of the MMP-12 rs652438 and MMP-3 rs35068180 polymorphisms with COPD.ConclusionsThe findings of this meta-analysis suggest that there is a risk of COPD associated with the MMP-9 rs3918242 and MMP-12 rs2276109 polymorphisms in certain ethnic groups.
BUDAYA PENDIDIKAN DI LINGKUNGAN KELUARGA DAN BOARDING SCHOOL
Authors: AlMunip  
Published: March 2021

Writing this article with viewpoints on the back of student ability of adjusting with culture of education and culture are in environment family adn Dormitory or boarding school. The methodology used is using a literature study and supported by experience. The result of article was first to know the sate and culture is in environment family, both know culture is in boarding school and third knows the difference between culture education in evironment family and boarding school
Early start of insulin therapy in type 2 diabetes mellitus: pros and cons
Authors: Яргин С.В. 
Published: March 2021

Своевременное назначение инсулина позволяет быстро нормализовать уровень гликемии. Показания к ранней инсулинотерапии часто возникают при дефиците инсулина у молодых пациентов с низкой массой тела, у пожилых больных с саркопенией, кахексией, хроническими инфекциями; при ранней манифестации микроагиопатических осложнений, при недостаточной эффективности двух- или трехкомпонентных схем; при выраженной симптоматике, связанной с гипергликемией. Адекватная инсулинотерапия уменьшает липо- и глюкозотоксичность, защищает бета-клетки, другие ткани и органы от повреждения. Вместе с тем существует мнение, что ввиду неблагоприятных эффектов экзогенного инсулина и появления новых сахароснижающих препаратов инсулинотерапию нужно начинать как можно позже. К нежелательным эффектам относятся риск гипогликемии, увеличения массы тела и, возможно, сердечно-сосудистых осложнений. Обсуждаются комбинации инсулинотерапии с другими сахароснижающими препаратами и ее особенности в пожилом возрасте. Отмечена тенденция увеличения с возрастом целевых уровней гликемии. Очевидно, что подход должен быть индивидуальным с учетом возраста, клинико-лабораторных показателей, сопутствующих заболеваний, предпочтений и возможностей пациентов.
The timely insulin administration can promptly normalize the blood glucose level. Indications for early insulin therapy include severe insulin deficiency often in young patients with low body weight; sarcopenia, cachexia and chronic infections especially in elder patients; early manifestation of microagiopathic complications, insufficient effectiveness of two- or three-component combinations of anti-diabetic drugs, severe symptoms associated with hyperglycemia. Adequate insulin therapy reduces lipo- and glucotoxicity, protects beta cells, other tissues and organs from damage. At the same time, there is an opinion that, in view of adverse effects of exogenous insulin and appearance of new anti-diabetic drugs, the insulin therapy should be started as late as possible. Adverse effects include the risk of hypoglycemia, weight gain and possibly also cardiovascular complications. Combinations of insulin with other hypoglycemic drugs and special features of insulin therapy in elder patients are discussed. There is a tendency for the target glycemic levels to increase with age. Obviously, the approach must be individual, taking into account age, clinical and laboratory data, comorbidities, preferences and possibilities of patients.
Diabetic peripheral polyneuropathy in the practice of a primary care physician
Authors: Комелягина Е.Ю. , Анциферов М.Б. 
Published: March 2021

Диабетическая периферическая сенсомоторная нейропатия относится к числу наиболее распространенных осложнений сахарного диабета. Диагностика диабетической периферической нейропатии состоит из оценки симптомов и клинического неврологического обследования с применением количественных тестов для оценки степени выраженности неврологических расстройств. В статье рассматриваются современные подходы к комплексному лечению болевой формы диабетической периферической нейропатии, начиная с компенсации углеводного обмена. Если, несмотря на нормализацию гликемии, у пациента сохраняются жалобы на боли или другие неприятные ощущения, необходимо назначать средства патогенетической либо симптоматической направленности с целью их уменьшения или полного исчезновения. Рассмотрены средства местной терапии для лечения диабетической периферической нейропатии, целью которой является купирование болевой симптоматики (антидепрессанты, противосудорожные средства, анальгетики, средства местного воздействия), а также средства патогенетической терапии, базирующиеся на воздействии на основные патогенетические компоненты диабетической периферической нейропатии (применение препаратов α-липоевой (тиоктовой) кислоты).
Diabetic peripheral sensorimotor neuropathy is one of the most common complications of diabetes mellitus. Diagnosis of diabetic peripheral neuropathy consists of symptom assessment and clinical neurologic examination using quantitative tests to assess the severity of neurologic disorders. The article discusses modern approaches to the complex treatment of pain form of diabetic peripheral neuropathy, starting with the compensation of carbohydrate metabolism. If, despite the normalization of glycemia, the patient continues to complain of pain or other unpleasant sensations, it is necessary to prescribe pathogenetic or symptomatic agents in order to reduce or completely disappear. The means of local therapy for the treatment of diabetic peripheral neuropathy, the purpose of which is to relieve pain symptoms (antidepressants, anticonvulsants, analgesics, topical agents), as well as pathogenetic therapy, based on the effect on the main pathogenetic components of diabetic peripheral neuropathy (use of drugs α-lipoic (thioctic) acid).
On the advisability of using antioxidants in the treatment of acute salpingooophoritis
Authors: Марзиева Т.А. , Рогожина И.Е. , Глухова Т.Н. 
Published: March 2021

В работе проведено изучение состояния процессов перекисного окисления липидов в крови больных с острым сальпингооофоритом, а также обоснование использования антиоксидантной терапии в комплексном лечении пациенток с указанной патологией. В группе из 50 пациенток с острым сальпингооофоритом проведено традиционное лечение, включающее антибактериальные средства в соответствии с клиническим протоколом диагностики и лечения воспалительных заболеваний органов малого таза (2015), противовоспалительную, дезинтоксикационную терапию (группа сравнения). У 50 пациенток с острым сальпингооофоритом аналогичная комплексная терапия была дополнена назначением препаратов со свойствами антиоксидантов (основная группа). При поступлении больных в стационар и после проведения терапии выполнена оценка состояния процессов перекисного окисления липидов в крови по содержанию продуктов липопероксидации в плазме крови и в эритроцитах, а также состоянию антиоксидантной системы крови. Результаты проведенных исследований свидетельствуют об активации перекисного окисления липидов и дестабилизации биологических мембран у больных с острым сальпингооофоритом. Показано, что использование антиоксидантной терапии в комплексном лечении больных с острым сальпингооофоритом способствует сокращению сроков лечения в стационаре и улучшает отдаленные результаты лечения пациенток с указанной патологией.
The study of the state of lipid peroxidation processes in patients with acute salpingo-oophoritis, as well as the rationale for the use of antioxidant therapy in the complex treatment of patients with this pathology, was carried out. In a group of 50 patients with acute salpingo-oophoritis, traditional treatment was performed, including antibacterial agents in accordance with the clinical protocol for the diagnosis and treatment of pelvic inflammatory diseases (2015), anti-inflammatory, detoxification therapy (comparison group). In 50 patients with acute salpingo-oophoritis, similar complex therapy was supplemented by the appointment of drugs with antioxidant properties (main group). When patients were admitted to the hospital and after therapy, the state of lipid peroxidation processes in the blood was assessed by the content of lipid hydroperoxides and malondialdehyde in blood plasma and in red blood cells, as well as the state of the antioxidant blood system. The results of the studies indicate the activation of lipid peroxidation and the destabilization of biological membranes in patients with acute salpingo-oophoritis. It is shown that the use of antioxidant therapy in the complex treatment of patients with acute salpingo-oophoritis helps to reduce the treatment time in the hospital and improves the long-term results of treatment for patients with this pathology.