bluuebunny/crossref_metadata_2025_split huggingface dataset:
Syndepositional hydrothermalism selectively preserves records of one of the earliest benthic ecosystems, Moodies Group (3.22 Ga), Barberton Greenstone Belt, South Africa
Authors: Reimann S. , Heubeck C.E. , Fugmann P. , Janse van Rensburg D.J. , Zametzer A. , Serre S.H. , Thomsen T.B. 
Published: April 2021

Abstract
The ~3.22 Ga Moodies Group, Barberton Greenstone Belt (BGB), South Africa, provides a unique window into Archaean sedimentary, magmatic and ecological processes. In the central BGB, a regional mafic complex, consisting of a genetically related major mafic sill, a peperitic dyke stockwork, and extensive basaltic lava flows affected thick quartzose sandstones of the Moodies Group. We argue that epithermal hydrothermalism associated with this magmatic event occurred, at least in part, syndepositionally and in places destroyed, in other places preserved the abundant benthic microbial mats in terrestrial- and coastal-facies sandstone of this unit. We differentiate four principal types of hydrothermal alteration: (1) Sericitization resulted from ubiquitous feldspar breakdown; (2) iron-oxide alteration replaced the original matrix by fine-grained iron oxide; (3) silicification replaced matrix and most non-silica grains by microcrystalline silica and locally preserved kerogenous microbial mats; and (4) hydraulic fracturing at shallow depth brecciated consolidated Moodies Group sandstone and created closely spaced, randomly oriented fractures and quartz-filled veins. Because stockwork intrusion locally interacted with unconsolidated water-saturated sediment and because the dykes connect the sill with the mafic lava but also follow zones of structural weakness, we suggest that hydrothermalism associated with this magmatic event occurred syndepositionally but was also – within the resolution of radiometric age data – contemporaneous with tight regional folding. We conclude that microbial organisms in Paleoarchaean coastal (tidal, estuarine) environments may have been formerly widespread, possibly even abundant, but are nearly nowhere preserved because they were easily degradable. Preservation of Early Archaean microbial mats in a thermal aureole in the central BGB was controlled by the “just right” degree of heating and very early hydrothermal silicification.
Efeitos da mobilização articular do conceito Mulligan na cervicalgia crônica em adultos
Authors: Montelo Elivelton Sousa , Braga Pedro Victor de Andrade , Silva Antonio Emerson Sousa da , Matos Ludmilla Karen Brandão Lima de 
Published: April 2021

Objetivo: Analisar os efeitos das técnicas de Mobilização do Conceito Mulligan (MCM) na cervicalgia crônica em adultos. Métodos: Revisão sistemática através das recomendações do “Preferred Reporting Items for Systematic Reviews and Meta-Analyses” (PRISMA), incluindo apenas Ensaios Clínicos Randomizados (ECR) com técnicas de MCM em participantes de 18 a 59 anos com cervicalgia grau I-II, com intensidades de dor e/ou incapacidades avaliadas por instrumentos validados, somente artigos com textos completos nos idiomas inglês, português ou espanhol, entre 2015 a 2020, nas bases PubMed, Web of Science, Science Direct, Embase, Scopus, Cochrane Library e PEDro, foi realizada a análise dos títulos e a leitura dos resumos para verificar os que seriam avaliados na íntegra. Essa etapa foi realizada por três pesquisadores de forma independente. Aplicou-se a ferramenta da Cochrane para avaliar a qualidade metodológica e risco de vieses. Resultados: Dos 65 estudos identificados, após a análise dos critérios de elegibilidade, selecionou-se 4 artigos para a síntese qualitativa. Considerações finais: MCM associadas com outras condutas proporcionam melhora na dor e incapacidades e indivíduos tratados com SNAGS de forma isolada obtiveram melhoras no limiar de pressão de dor.
Need Analysis for Developing Writing Skill Materials Using Facebook for English Undergraduate Students
Authors: Sakkir Geminastiti , Dollah Syarifuddin , Arsyad Safnil , Ahmad Jamaluddin 
Published: April 2021

This research is aiming at giving a contribution to the lecturersâ€™ knowledge on the design materials in using social media Facebook in teaching writing process to English Department students. Before conducted the developing module for Facebook-based writing instructional course, we surveyed and explored the studentâ€™s need. The stages of this research consisted of need analysis and document analysis. We conducted needs analysis to 141 English students and 2 lecturers of writing. Data were collected using need analysis questionnaire and interview. The analyzed documents in this research were lesson plan, syllabus and the existing textbooks. The data from questionnaire and interview were analyzed in quantitative and qualitative methods. The results concluded that: first, needs analysis is the basic of developing module for Facebook-based writing instructional course, in order that the material can be related to the studentsâ€™ needs, levels and lecturersâ€™ perception. The result of students need found urgent to develop module for facebook-based writing instructional course through the following criteria of interactive, self-contained, user friendly, online supporting, online social media, authentic, environmentally friendly, formal and informal environments, online evaluation, presented in visualÂ aids, supportÂ and facilitate the studentsâ€™Â academic and non-academic writing activities, topics of the materials should be interesting which provides a cultural background of students, the materials should be implemented by applying vocabulary, reading texts, grammar and basic skills in writing process, implemented in beginner level (Writing 1), used in class and out- class and the materials globally/ international context. Second, the lecturersâ€™ desires in teaching writing are to improve the studentsâ€™ skill to comprehend the materials. Third, the existing materials are unsuitable for the students, they prefer learning facilitated by electronic social media, Facebook, so they will more motivate in write.
MODEL REGRESI COX UNTUK MENGANALISIS PENGARUH FAKTOR ASUPAN MAKANAN TERHADAP RISIKO KEKAMBUHAN ENDOMETRIOSIS
Authors: Eliyati Ning , Maiyanti Sri Indra , Dwipurwani Oki , Hamidah Shaly Wanda 
Published: April 2021

This research purpose is to analyze the relationship between food intake factors (fruit, soy, milk, caffeine, red meat, garlic, ginger, seafood, cheese, green tea, brown rice, wheat, potatoes, bean sprouts, mustard greens, soft drinks and alcohol) on hazard of endometriosis recurrence, using the Cox proportional hazard model backward method. The results of the food intake factors that significantly reduced the risk of endometriosis recurrence are fruit 1-4 times/week (p-value 0.01), fruit 5-7 1-4 times/week (p-value 0.08), mustard greens 1-7 times/week (p-value 0.006), bean sprouts 3-7 (p-value 0.007) and seafood times/week. Factors that increase the risk of endometriosis recurrence are consumption of milk 3-4 times/week (p-value 0.004), seafood 1-2 times (p-value 0.00), soy 1-2 times/week (p-value 0.002), and 3-7 times/week (p-value 0.001). Soy consumption 1-2 and 3-7 times/week are likely to relapse 30.3 and 43.9 times compared to soy consumption <1 times/week. Consumption of milk 3-4 times/week has a risk of relapse 24 times compared to consume milk <1 times/week
Food Experiences and Dietary Patterns of International Students at a Canadian University
Authors: Pilli Bhanu , Slater Joyce 
Published: April 2021

Purpose: Postsecondary students who move to a new country to continue their education experience a drastic shift in food landscape, often resulting in unhealthy dietary adaptations. Methods: This mixed-method study explored the eating experiences and dietary patterns of 30 international students attending a Canadian university. Data were collected through focus groups that were analyzed thematically and dietary records analyzed for compliance with Canada’s Food Guide for Healthy Living (2007). Results: Results showed that many participants want to maintain home country food traditions, yet their new independent living status and novel food environments led to changes in dietary habits. Limited food skills, busy schedules, reduced access to familiar foods, and fast-food environments contributed to unhealthy eating patterns. These perceptions were reflected in the high consumption of “other”, less nutritious foods and low servings of fruits and vegetables, milk products and alternatives, and grain products. Conclusions: These findings show that international university students face dual challenges of transitioning into independent living without sufficient food skills and family supports, and exposure to unfamiliar and unhealthy food environments. Resources need to be developed for newly enrolled international students that emphasize food awareness, food skills, and healthy eating habits.
Basic Reproduction Number of Tuberculosis Spread Model in Lamongan With DOTS Strategy
Authors: Alfan Aris , Resmi Fitroh , Dewi Nihaya Alivia Coraima 
Published: April 2021

Tuberculosis (TB) will be a serious threat if not handled quickly and appropriately. The relatively long treatment in time and the high risk of death is a challenge in controlling the spread of this disease. The DOTS (Directly Observed Treatment Short-course) strategy is considered capable of controlling the spread of TB because of the high success rate, reaching 91%. The mathematical model of the spread of TB has been widely studied to determine the potential for the spread of this disease in an area. The purpose of this study is to build a model of tuberculosis spread in Lamongan to determine the rate of its spread and to predict whether it will be endemic or not. Using disease spread mathematical model type SEITR, this research has examined based on 2018 and 2019 data from the Lamongan health office then simulates the result. The research begins with the construction of the model followed by a stability analysis of the model by determining the basic reproduction number ( ), which is simulated after the parameter approach was carried out. From the simulation results, the result shows that means that TB will not endemic in Lamongan. Besides, the results of the effect of parameter ω on I(t) were obtained, which concluded that seeking and treating active TB alone would only reduce infected individuals but not reduce the length of time TB spread. Identification of the effect of parameter φ on I(t) has also been carried out which results in the conclusion that more treatment for susceptible individuals, in addition to reducing the number of infected individuals, will also reduce the length of time TB spreads in that area. This result will be a good suggestion for the government to deal faster with tuberculosis transmission.
Phase II (NAVIGATE-AD study) Results of LY3202626 Effects on Patients with Mild Alzheimer’s Disease Dementia
Authors: Lo Albert C. , Evans Cynthia Duggan , Mancini Michele , Wang Hong , Shcherbinin Sergey , Lu Ming , Natanegara Fanni , Willis Brian A. 
Published: April 2021

Background: LY3202626 is a small molecule inhibitor of β-site amyloid precursor protein cleaving enzyme (BACE)1 shown to reduce amyloid-β (Aβ)1–40 and Aβ1–42 concentrations in plasma and cerebrospinal fluid developed for the treatment of Alzheimer’s disease (AD). Objective: To assess the change from baseline in flortaucipir positron emission tomography (PET) after treatment with LY3202626 compared with placebo in patients with mild AD dementia. Methods: Patients received daily 3 mg or 12 mg doses of LY3202626 or placebo for 52 weeks. The primary outcome was assessment of cerebral neurofibrillary tangle load by flortaucipir PET. The study was terminated early following an interim analysis due to a low probability of identifying a statistically significant slowing of cognitive and/or functional decline. Results: A total of 316 patients were randomized and 47 completed the study. There was no statistically significant difference between placebo and either dose of LY3202626 from baseline to 52 weeks, or in annualized change for flortaucipir PET. There was no clinically meaningful difference between placebo and LY3202626 doses on efficacy measures of cognition and function. No deaths or serious adverse events considered related to LY3202626 were reported. A statistically significant increase in treatment-emergent adverse events in the psychiatric disorders system organ class was reported for both LY3202626 doses compared to placebo. Conclusion: LY3202626 tested at doses generating 70–90% BACE inhibition was generally well tolerated in this study. LY3202626 treatment did not result in a clinically significant change in cerebral tau burden as measured by flortaucipir nor in change of functional or cognitive decline compared to placebo.
Incidental Prostate Cancer in Radical Cystoprostatectomy Specimens is Associated with Worse Overall Survival
Authors: Kimura Takahiro , Onuma Hajime , Sato Shun , Inaba Hiroyuki , Fukuokaya Wataru , Urabe Fumihiko , Kimura Shoji , Tashiro Kojiro , Tsuzuki Shunsuke , Miki Jun , Furuta Akira , Takahashi Hiroyuki , Egawa Shin 
Published: April 2021

BACKGROUND: The impact of incidental prostate cancer (IPC) on oncological outcomes after radical cystoprostatectomy (RCP) specimens from patients with bladder cancer (BC) remains controversial. This relationship has not been well elucidated in Asian countries, where the incidence of prostate cancer has recently shown dramatic increases. OBJECTIVES: This study retrospectively compared pathological features and oncological outcomes between BC patients with and without IPC in the RCP specimens. METHODS: This study included 142 men who underwent RCP for BC. Men who were previously diagnosed with prostate cancer were excluded. Each prostate gland and seminal vesicle was processed as whole mounts and 4-mm close-step sectioning was performed. A single genitourinary pathologist diagnosed IPC. The pathological features and oncological outcomes such as overall survival (OS), bladder cancer-specific survival (BCSS), and progression-free survival (PFS) were compared between patients with IPC (IPC+group, n = 45) and without IPC (IPC- group, n = 97). P values less than 0.05 considered to indicate statistical significance for patients’ characteristics. Because of multi-primary endpoint, P values less than 0.0167 was considered statistical significance for oncological outcomes. RESULTS: We detected IPC in 45 RCP specimens (31.6%). Patients in the IPC- group were significantly younger at surgery than those in the IPC+group ( P < 0.001). The pathological features of the RCP specimens did not differ significantly. In multivariable analyses, presence of IPC was significantly associated with worse OS ( P = 0.005), but not with either BCSS or PFS ( P = 0.038 and 0.326, respectively). In Kaplan–Meier analyses, OS tended to be longer in the IPC- group than that in the IPC+group (NR vs 65 months, P = 0.0017). CONCLUSIONS: Our results suggested significantly better OS in patients without IPC than that in those with IPC.
A STUDY ON RESPIRATORY COMPLICATIONS AND ITS OUTCOME IN ACUTE PANCREATITIS
Authors: Valsalan Abhijith , Kavalakat Alfie J , Gopal Gowri , P John Thomas , Vakiyath Rashifa , M V Suresh 
Published: April 2021

Background: Respiratory complications are frequent in acute pancreatitis, and respiratory dysfunction, presenting as Acute lung injury (ALI) or Acute Respiratory Distress Syndrome (ARDS), is a major component of multiple organ dysfunction syndrome (MODS), with a frequent need for ventilator support, which contributes to early death in severe acute pancreatitis. The current study was done with the objective of assessing the morbidity and mortality of acute pancreatitis cases with respiratory complications and to find out whether there is any association between the aetiology of acute pancreatitis and respiratory complications.
Methodology: It was a prospective observational study conducted in a tertiary care centre in Kerala. All participants admitted with symptoms suggestive of acute pancreatitis were screened for potential enrolment. The inclusion criteria employed were that the patients should be aged above 18 years, and presenting with the first episode of pancreatitis, irrespective of aetiology. All the patients who were admitted were monitored daily for the worsening of any respiratory complications and provided with adequate respiratory supports.
Results: Out of the 101 participants recruited, males were 84.2%. Mean (SD) age was 42.1 (11.4) years. Majority of cases (61%) had alcoholic aetiology. Fourteen patients required high flow nasal oxygen support, four patients were given face mask support, five patients required ventilator support and three patients required tracheostomy support. Respiratory complications and requirement of support were found to be associated with higher morbidity as well as mortality. Respiratory complications were higher in those with alcoholic etiology but this was not significant in univariate analysis.
Conclusion: Respiratory complications pose challenges in clinical course of acute pancreatitis in terms of morbidity as well as mortality. Aetiology did not seem to play a major role in development of respiratory complications.
CLINICAL AND RADIOGRAPHIC EVALUATION OF INTENTIONAL REPLANTATION OF TEETH UTILIZING ATRAUMATIC EXTRACTION TECHNIQUE AND BIODENTIN AS ROOT END RESTORATIVE MATERIAL. AN IN VIVO STUDY
Authors: Tomer Anil K. , Mushtaq Hysum , Tyagi Ayush , Poonia Sachin , Sabharwal Geetika , Singh Supriya , Jain Shivangi 
Published: April 2021

Aims: Aim is to evaluate the clinical and radiographic outcome of Intentional Replantation of teeth utilizing Atraumatic extraction technique and Biodentin as root end restorative material
Materials and Methods: Any patients irrespective of age & sex who reported to the Department of Conservative Dentistry & Endodontics, D. J. College of Dental Sciences & Research with the post endodontic treatment periapical pathology where orthograde retreatment and apical surgery was unfeasible or declined by patients and where extraction be the last resort was selected for the procedure. Informed consent was taken. Retention and healed status without complications (periapical radiolucency, external root resorption, ankylosis, signs/symptoms, probing <6 mm) was recorded and analyzed with Kaplan-Meier survival analysis and Cox proportional hazard regression model (P < .05). Bivariate associations of the investigated variables with the main complications (ankylosis, periapical radiolucency, external root resorption) evaluated.
Results: Cumulative healed rates from 60% at 6 months to 92% at 12months seen. Complications leading to extraction observed in 1 of 15 attending teeth. The Kaplan-Meier survival function suggested an expected 1-year cumulative retention rate of 92%. Among the 15 teeth, 1 tooth with complication was due to persistent periapical radiolucency and mobility.
Null hypothesis was that IR is to preserve the natural dentition, there by upholding the main goal of Conservative treatment.
Conclusions: Within the limitations of this study, after analyzing the results and obtaining a complete follow up of 12 months radiographically and clinically, it can be concluded that Intentional replantation is an alternative treatment and should be included in the savior procedures as it has shown a success rate of 92%.
Keywords: endodontic complications, intentional replantation, physics forceps, Biodentin
Pengetahuan Ibu tentang Manfaat Bermain pada Perkembangan Anak Usia balita di Masa Pandemi Covid-19
Authors: Melati Rosa , Rahayu Metha Kemala 
Published: April 2021

During the Covid-19 pandemic, the government implemented the PSBB (Large-Scale Social Restrictions), which meant that no outdoor activities for the community, including children. Children's activities in the surrounding environment experience changes and restrictions. The design of this study was an analytic design with a cross sectional approach. The population of this study were all mothers who have children aged 1-5 years in Jatiluhur, and a sample of 50 respondents. The data collection tool was a questionnaire. Univariate and bivariate data analysis using the Spearmen Rank correlation. The results of this study are that the majority of the mother's knowledge level about the benefits of playing for toddlers (aged 1-5 years) is in the good category (42 mothers: 87.5%) and the development of toddlers (ages 1-5 years) the majority is in the normal category of 59 people ( 94.5%). It is shown by the results of statistical tests using the Spearmen Rank with z count 3.181 z table (1.96). The conclusion from this study is that there is a relationship between the level of maternal knowledge about the benefits of playing with the development of toddlers (ages 1-5 years). Keywords: benefits of playing, knowledge, development
Gambaran Karakteristik Siswa SMP Dalam Mengontrol Emosional Di Kota MALANG
Authors: Rahayu Hastutiningtyas Wahidyanti , Maemunah Neni , Lakar Rolianto Ngganja 
Published: April 2021

ABSTRACT The development of adolescence is always looking for new things and identity, this will make the youth begin to understand themselves when they have the ability to regulate and control their emotions and will adversely affect if they are not able to multiply their emotions. This study aims to know the characteristics of junior high school students in emotional control in Malang. This type of research is descriptive analytics. The respondents of the study were students at SMP Shalahuddin Malang, obtained a population of 65 respondents and a sample of 56 respondents taken with simple random sampling techniques. The data was collected using questionnaires. The results of the analysis are univariate and presented by frequency distribution. The results showed that of the 28 young men at Shalahuddin Junior High School in Malang, most had emotional control in the moderate category (71.43%) and that of the 28 young women at Smp Shalahuddin Malang most had emotional control in the high category (64.29%). In educational institutions, there needs to be knowledge about the characteristics of junior high school students in controlling emotions in Malang so that they know how to cope with students who cannot control emotions properly. Keywords : Student Characteristics, and Emotional Control ABSTRAK Masa perkembangan remaja selalu mencari hal yang baru dan identitas dirinya, hal ini akan membuat remaja mulai memahami dirinya ketika memiliki kemampuan dalam mengatur dan mengendalikan emosinya dan akan berdampak buruk bila tidak mampu mengalikan emosinya. Penelitian ini bertujuan mengetahui gambaran karakteristik siswa SMP dalam mengontrol emosional di Kota Malang. Jenis penelitian ini adalah deskriptif analitik. Responden penelitian adalah siswa di SMP Shalahuddin Kota Malang, didapatkan populasi sebanyak 65 responden dan sampel sebanyak 56 responden yang diambil dengan teknik pengambilan simple random sampling. Data dikumpulkan dengan menggunakan kuesioner. Hasil analisis secara univariat dan disajikan secara distribusi frekuensi. Hasil menunjukkan bahwa dari 28 remaja putra di SMP Shalahuddin Kota Malang sebagian besar memiliki kontrol emosi pada kategori sedang (71,43%) dan bahwa dari 28 remaja putri di SMP Shalahuddin Kota Malang sebagian besar memiliki kontrol emosi pada kategori tinggi (64,29%). Pada instansi pendidikan perlu adanya pengetahuan tentang karakteristik siswa SMP dalam mengontrol emosional di Kota Malang sehingga mengetahui cara mengatasi siswa yang tidak bisa mengontrol emosi secara baik. Kata kunci : Karakteristik siswa, dan Mengontrol emosional