bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Analysis of Paper-Based and Web-Based Versions of the National Comprehensive Cancer Network-Functional Assessment of Cancer Therapy-Breast Cancer Symptom Index (NFBSI-16) Questionnaire in Breast Cancer Patients: Randomized Crossover Study
Authors: Ma Jinfei , Zou Zihao , Pazo Emmanuel Eric , Moutari Salissou , Liu Ye , Jin Feng 
Published: January 2021

Background
Breast cancer remains the most common neoplasm diagnosed among women in China and globally. Health-related questionnaire assessments in research and clinical oncology settings have gained prominence. The National Comprehensive Cancer Network–Functional Assessment of Cancer Therapy–Breast Cancer Symptom Index (NFBSI-16) is a rapid and powerful tool to help evaluate disease- or treatment-related symptoms, both physical and emotional, in patients with breast cancer for clinical and research purposes. Prevalence of individual smartphones provides a potential web-based approach to administrating the questionnaire; however, the reliability of the NFBSI-16 in electronic format has not been assessed.

Objective
This study aimed to assess the reliability of a web-based NFBSI-16 questionnaire in breast cancer patients undergoing systematic treatment with a prospective open-label randomized crossover study design.

Methods
We recruited random patients with breast cancer under systematic treatment from the central hospital registry to complete both paper- and web-based versions of the questionnaires. Both versions of the questionnaires were self-assessed. Patients were randomly assigned to group A (paper-based first and web-based second) or group B (web-based first and paper-based second). A total of 354 patients were included in the analysis (group A: n=177, group B: n=177). Descriptive sociodemographic characteristics, reliability and agreement rates for single items, subscales, and total score were analyzed using the Wilcoxon test. The Lin concordance correlation coefficient (CCC) and Spearman and Kendall τ rank correlations were used to assess test-retest reliability.

Results
Test-retest reliability measured with CCCs was 0.94 for the total NFBSI-16 score. Significant correlations (Spearman ρ) were documented for all 4 subscales—Disease-Related Symptoms Subscale–Physical (ρ=0.93), Disease-Related Symptoms Subscale–Emotional (ρ=0.85), Treatment Side Effects Subscale (ρ=0.95), and Function and Well-Being Subscale (ρ=0.91)—and total NFBSI-16 score (ρ=0.94). Mean differences of the test and retest were all close to zero (≤0.06). The parallel test-retest reliability of subscales with the Wilcoxon test comparing individual items found GP3 (item 5) to be significantly different (P=.02). A majority of the participants in this study (255/354, 72.0%) preferred the web-based over the paper-based version.

Conclusions
The web-based version of the NFBSI-16 questionnaire is an excellent tool for monitoring individual breast cancer patients under treatment, with the majority of participants preferring it over the paper-based version.
Lexicon Development for COVID-19-related Concepts Using Open-source Word Embedding Sources: An Intrinsic and Extrinsic Evaluation
Authors: Parikh Soham , Davoudi Anahita , Yu Shun , Giraldo Carolina , Schriver Emily , Mowery Danielle 
Published: January 2021

Background
Scientists are developing new computational methods and prediction models to better clinically understand COVID-19 prevalence, treatment efficacy, and patient outcomes. These efforts could be improved by leveraging documented COVID-19–related symptoms, findings, and disorders from clinical text sources in an electronic health record. Word embeddings can identify terms related to these clinical concepts from both the biomedical and nonbiomedical domains, and are being shared with the open-source community at large. However, it’s unclear how useful openly available word embeddings are for developing lexicons for COVID-19–related concepts.

Objective
Given an initial lexicon of COVID-19–related terms, this study aims to characterize the returned terms by similarity across various open-source word embeddings and determine common semantic and syntactic patterns between the COVID-19 queried terms and returned terms specific to the word embedding source.

Methods
We compared seven openly available word embedding sources. Using a series of COVID-19–related terms for associated symptoms, findings, and disorders, we conducted an interannotator agreement study to determine how accurately the most similar returned terms could be classified according to semantic types by three annotators. We conducted a qualitative study of COVID-19 queried terms and their returned terms to detect informative patterns for constructing lexicons. We demonstrated the utility of applying such learned synonyms to discharge summaries by reporting the proportion of patients identified by concept among three patient cohorts: pneumonia (n=6410), acute respiratory distress syndrome (n=8647), and COVID-19 (n=2397).

Results
We observed high pairwise interannotator agreement (Cohen kappa) for symptoms (0.86-0.99), findings (0.93-0.99), and disorders (0.93-0.99). Word embedding sources generated based on characters tend to return more synonyms (mean count of 7.2 synonyms) compared to token-based embedding sources (mean counts range from 2.0 to 3.4). Word embedding sources queried using a qualifier term (eg, dry cough or muscle pain) more often returned qualifiers of the similar semantic type (eg, “dry” returns consistency qualifiers like “wet” and “runny”) compared to a single term (eg, cough or pain) queries. A higher proportion of patients had documented fever (0.61-0.84), cough (0.41-0.55), shortness of breath (0.40-0.59), and hypoxia (0.51-0.56) retrieved than other clinical features. Terms for dry cough returned a higher proportion of patients with COVID-19 (0.07) than the pneumonia (0.05) and acute respiratory distress syndrome (0.03) populations.

Conclusions
Word embeddings are valuable technology for learning related terms, including synonyms. When leveraging openly available word embedding sources, choices made for the construction of the word embeddings can significantly influence the words learned.
Mobile HIV Testing Through Social Networking Platforms: Comparative Study
Authors: Chiou Piao-Yi , Ko Nai-Ying , Chien Chien-Yu 
Published: January 2021

Background
Improving HIV screening in key populations is a crucial strategy to achieve the goal of eliminating AIDS in 2030. Social networking platforms can be used to recruit high risk-taking men who have sex with men (MSM) to promote the delivery of voluntary counseling and testing (VCT) as mobile HIV testing. Therefore, client recruitment and availability of mobile HIV testing through social networking platforms requires further evaluation.

Objective
The aim of this study is to compare the effects of targeting high risk-taking MSM and HIV case finding between two mobile HIV testing recruitment approaches: through the traditional website-based approach and through social networking platforms.

Methods
A comparative study design and propensity score matching was applied. The traditional VCT model, that is, the control group, recruited MSM through a website, and a trained research assistant visited the walk-in testing station at a gay village on Friday and Saturday nights. The social networking VCT model, the experimental group, recruited MSM from social networking platforms by periodically reloading into and conducting web-based discussions on dating apps and Facebook. The participants then referred to others in their social networks via a popular messenger app in Taiwan. The test was conducted at a designated time and place during weekdays by a trained research assistant. Across both modes of contact, before the mobile HIV testing, participants needed to provide demographic characteristics and respond to a questionnaire about HIV risk-taking behaviors.

Results
We recruited 831 MSM over 6 months, with a completion rate of 8.56% (616/7200) in the traditional VCT model and 20.71% (215/1038) in the social networking VCT model. After propensity score matching, there were 215 MSM in each group (mean age 29.97, SD 7.61 years). The social networking model was more likely to reach MSM with HIV risk-taking behaviors, that is, those seeking sexual activity through social media, having multiple sexual partners and unprotected anal intercourse, having experience of recreational drug use, and never having or not regularly having an HIV test, compared with the traditional model. HIV positive rates (incidence rate ratio 3.40, 95% CI 1.089-10.584; P=.03) and clinic referral rates (incidence rate ratio 0.03, 95% CI 0.001-0.585; P=.006) were significantly higher among those in the social networking VCT model than in the traditional VCT model.

Conclusions
Through effective recruitment strategies on social networking platforms, the social networking VCT mode can be smoothly promoted, as compared with the traditional VCT model, to target high risk-taking MSM and increase testing outcomes.
Differences in Basic Life Support Knowledge Between Junior Medical Students and Lay People: Web-Based Questionnaire Study
Authors: Sturny Ludovic , Regard Simon , Larribau Robert , Niquille Marc , Savoldelli Georges Louis , Sarasin François , Schiffer Eduardo , Suppan Laurent 
Published: January 2021

Background
Early cardiopulmonary resuscitation and prompt defibrillation markedly increase the survival rate in the event of out-of-hospital cardiac arrest (OHCA). As future health care professionals, medical students should be trained to efficiently manage an unexpectedly encountered OHCA.

Objective
Our aim was to assess basic life support (BLS) knowledge in junior medical students at the University of Geneva Faculty of Medicine (UGFM) and to compare it with that of the general population.

Methods
Junior UGFM students and lay people who had registered for BLS classes given by a Red Cross–affiliated center were sent invitation links to complete a web-based questionnaire. The primary outcome was the between-group difference in a 10-question score regarding cardiopulmonary resuscitation knowledge. Secondary outcomes were the differences in the rate of correct answers for each individual question, the level of self-assessed confidence in the ability to perform resuscitation, and a 6-question score, “essential BLS knowledge,” which only contains key elements of the chain of survival. Continuous variables were first analyzed using the Student t test, then by multivariable linear regression. Fisher exact test was used for between-groups comparison of binary variables.

Results
The mean score was higher in medical students than in lay people for both the 10-question score (mean 5.8, SD 1.7 vs mean 4.2, SD 1.7; P<.001) and 6-question score (mean 3.0, SD 1.1 vs mean 2.0, SD 1.0; P<.001). Participants who were younger or already trained scored consistently better. Although the phone number of the emergency medical dispatch center was well known in both groups (medical students, 75/80, 94% vs lay people, 51/62, 82%; P=.06), most participants were unable to identify the criteria used to recognize OHCA, and almost none were able to correctly reorganize the BLS sequence. Medical students felt more confident than lay people in their ability to perform resuscitation (mean 4.7, SD 2.2 vs mean 3.1, SD 2.1; P<.001). Female gender and older age were associated with lower confidence, while participants who had already attended a BLS course prior to taking the questionnaire felt more confident.

Conclusions
Although junior medical students were more knowledgeable than lay people regarding BLS procedures, the proportion of correct answers was low in both groups, and changes in BLS education policy should be considered.
Quantifying the Influence of Delay in Opinion Transmission of COVID-19 Information Propagation: Modeling Study
Authors: Yin Fulian , Shao Xueying , Ji Meiqi , Wu Jianhong 
Published: January 2021

Background
In a fast-evolving public health crisis such as the COVID-19 pandemic, multiple pieces of relevant information can be posted sequentially on a social media platform. The interval between subsequent posting times may have a different impact on the transmission and cross-propagation of the old and new information that results in a different peak value and a final size of forwarding users of the new information, depending on the content correlation and whether the new information is posted during the outbreak or quasi–steady-state phase of the old information.

Objective
This study aims to help in designing effective communication strategies to ensure information is delivered to the maximal number of users.

Methods
We developed and analyzed two classes of susceptible-forwarding-immune information propagation models with delay in transmission to describe the cross-propagation process of relevant information. A total of 28,661 retweets of typical information were posted frequently by each opinion leader related to COVID-19 with high influence (data acquisition up to February 19, 2020). The information was processed into discrete points with a frequency of 10 minutes, and the real data were fitted by the model numerical simulation. Furthermore, the influence of parameters on information dissemination and the design of a publishing strategy were analyzed.

Results
The current epidemic outbreak situation, epidemic prevention, and other related authoritative information cannot be timely and effectively browsed by the public. The ingenious use of information release intervals can effectively enhance the interaction between information and realize the effective diffusion of information. We parameterized our models using real data from Sina Microblog and used the parameterized models to define and evaluate mutual attractiveness indexes, and we used these indexes and parameter sensitivity analyses to inform optimal strategies for new information to be effectively propagated in the microblog. The results of the parameter analysis showed that using different attractiveness indexes as the key parameters can control the information transmission with different release intervals, so it is considered as a key link in the design of an information communication strategy. At the same time, the dynamic process of information was analyzed through index evaluation.

Conclusions
Our model can carry out an accurate numerical simulation of information at different release intervals and achieve a dynamic evaluation of information transmission by constructing an indicator system so as to provide theoretical support and strategic suggestions for government decision making. This study optimizes information posting strategies to maximize communication efforts for delivering key public health messages to the public for better outcomes of public health emergency management.
TOTAL ERITROSIT DAN LEUKOSIT BROILER BETINA SETELAH PEMBERIAN JINTAN HITAM (Nigella sativa) SEBAGAI IMUNOMODULATOR DALAM AIR MINUM
Authors: Hariyani Noven , Siswanto Siswanto , Suharyati Sri , Santosa Purnama Edy 
Published: January 2021

The study aimed to determine the effects of black cumin extract (Nigella sativa) and determine the optimal dose of black cumin extract (Nigella sativa) on total erythrocytes and leukocytes broilers. This research was conducted from December 2019 to January 2020 at the Integrated Field Laboratory Unit of the Faculty of Agriculture, University of Lampung. The research data were analyzed at Pramitra Biolab Indonesia Laboratory, Bandar Lampung. The research material was 60 female broilers (strain Cobb CP 707). This study used a Completely Randomized Design with 4 treatments and 3 replications. The treatments in this study were drinking water without Nigella sativa (P0), drinking water with Nigella sativa 36 mg/kg BW/day (P1), drinking water with Nigella sativa 72 mg/kg BW/day (P2) and drinking water with Nigella sativa 144 mg/kg BW/day (P3). Data obtained from observations were arranged in the form of simple tabulations and displayed in the form of histograms for descriptive analysis. Research showed that female broilers given black cumin (Nigella sativa) in their drinking water affected on the total erythrocytes which was in the normal range and the total leukocytes which were above the normal range in all treatment. The best dose of black cumin (Nigella sativa) in drinking water for each parameters was 144 mg/kg BW/day for total erythrocytes and 72 mg/kg BW/day for total leukocytes.
Keywords: Black cumin (Nigella sativa), Erythrocytes, Female broilers, Immunomodulator , Leukocytes
FAKTOR-FAKTOR YANG MEMPENGARUHI SERVICE PER CONCEPTION PADA SAPI KRUI DI KECAMATAN PESISIR SELATAN
Authors: Fauzi Nur Fadilah Rizki , Hartono Madi , Siswanto Siswanto , Suharyati Sri 
Published: January 2021

Research on service per conception (S/C) of Krui Cattles in Pesisir Selatan Regency was carried out in December 2019 using two inseminators collection data, 75 farmers and 166 Krui Cattles that have been artificially inseminated. The purpose of this study was to determine: 1) the S/C value of Krui cattle in the Pesisir Selatan District, 2) the factors and its magnitude that influence the S/C of Krui cattle in Pesisir Selatan Regency. Data was analysed with multiple regression using SPSS (Statistical Package for Social Science) programs. The results showed that the S/C value of Krui Cattles in Pesisir Selatan Regency was 1.53�0.71. The factors that affected the S/C value of Krui Cattless in Pesisir Selatan Regency were derived from the variable of farmers and livestock. At the farmer level the factors that influence wee the type of forage that is negatively associated with a factor of 0.229, the shape of the cage wall which is negatively associated with 0.287, and the sanitation of the cage that is negatively associated with 0.355. Factors influencing S/C values at the livestock level were negative associated body condition scores (BCS) of 0.429, age of first mated was negative associations of 0.039, and estrus postpartum negative associations of 0.118.
Keywords: Factors and factors value, Service per conception, Krui cattle
EFISIENSI IRIGASI BERDASARKAN KONDISI SALURAN DI DAERAH IRIGASI PUNGGUR UTARA
Authors: Sari Dwi Meyta , Wahono Endro Prasetyo , Kusumastuti Dyah Indriana 
Published: January 2021

Efisiensi saluran didefinisikan sebagai perbandingan antara jumlah air yang masuk pada hulu saluran dengan jumlah air yang tersedia pada hilir yang dinyatakan dalam persentase. Air irigasi dalam perjalanannya untuk sampai ke petakan sawah mengalami kehilangan air yang dapat disebabkan oleh beberapa faktor diantaranya rembesan, evaporasi dan faktor lain seperti adanya eksploitasi air irigasi oleh warga sekitar. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana kondisi fisik saluran sekunder di BF 3 sampai dengan BF 5 dan nilai efisiensi yang tercapai, serta untuk mengetahui seberapa besar pengaruh kehilangan air akibat faktor rembesan, evaporasi dan faktor lainnya. Penelitian ini dilakukan dengan mengidentifikasi kondisi saluran kemudian menghitung efisiensi yang tercapai serta kehilangan airnya. Hasil analisis menunjukkan bahwa kerusakan pada saluran BF 3 – BF 4 termasuk dalam kategori rusak ringan dengan efisiensi rata – rata yang tercapai sebesar 97,41%. Persentase kehilangan air pada saluran BF 3 – BF 4 akibat faktor rembesan sebesar 53,74%, faktor evaporasi sebesar 0,69% dan faktor lain – lainnya sebesar 46,57%. Sedangkan kondisi pada saluran BF 4 – BF 5 termasuk ke dalam kategori baik dengan efisiensi yang tercapai sebesar sebesar 87,44%. Persentase kehilangan air pada saluran BF 4 – BF 5 akibat faktor rembesan sebesar 27,85%, faktor evaporasi sebesar 0,78% dan faktor lain – lainnya sebesar 71,37%.
ПСИХОТЕРАПЕВТИЧЕСКИЕ ОСОБЕННОСТИ МЕТОДА ГИДРОРЕАБИЛИТАЦИИ БОЛЬНЫХ С ОГРАНИЧЕННЫМИ ВОЗМОЖНОСТЯМИ ЗДОРОВЬЯ (ОВЗ)
Authors: Власов Ян , Гаврилов Владимир , Ипатов Олег , Клименко Екатерина , Чернышев Александр 
Published: January 2021

В данной работе предлагается на рассмотрение метод психотерапевтической гидрореабилитации больных с ограниченными возможностями здоровья (ОВЗ) и инвалидов больных рассеянным склерозом. Концепция рассмотрена примере сценария реабилитации, который в динамике выглядит следующим образом:
•	мотивация уверенности в своих силах и возможностях;
•	мотивация на ремиссию с текстом, где ведущая роль отводится пребыванию в воде - уводящей пациента в мир где он легко управляет своим телом;
•	обучение плаванию сертифицированными инструкторами и тренерами для работы с людьми ОВЗ;
•	понимание пациентом того факта, его фантазии могут быть реализованы в реальности; например – пациентка первой группы инвалидности по рассеянному склерозу, ранее занимавшаяся бальными танцами – могла потанцевать в воде; больной рассеянным склерозом первой группы инвалидности – научился плавать; пациент с черепно-мозговой травмой стал передвигаться без страха и напряжения в реальных условиях – ставшей значительно более доступной – среды.
Graduate Employability and Digital Entrepreneurship in the Era of IR 4.0
Authors: Nayan Surina , Shafie Latisha Asmaak , Chulan Majdah , Zakaria Fazmawati , Nayan Suhaimi 
Published: January 2021

This is a conceptual paper on virtual entrepreneurship that can be ventured by graduates in Malaysia in the IR 4.0 era. The study defines what virtual entrepreneurship is, its advantages, reviews of some literature on the topic, IR 4.0 and its effects to Malaysian businesses in general. Besides, the paper also focuses on types of virtual entrepreneurship that Malaysian graduates can explore. They can venture into cyber-security analyst positions, can produce and innovate IoT tools and solutions, be online retail consigners, can be content creators for Instagram, Twitter and Facebook for companies that need their services, can do freelance copywriting and editing for new companies or traditional companies, can become social media influencers, can become YouTube personalities, can assume the role of digital strategy experts and they can also offer digitalized services and solutions. As a result, they will not depend a lot on working with the government or private sector. It is a well-known fact that getting a job in an office is difficult nowadays. They can find their own income to continue supporting their lives in today’s challenging world when they are aware of the opportunities offered to them using the virtual world. They can actually venture into areas that do not require them to commute to their offices every day. Instead, they can just work in front of their laptop or pc or tab which is connected to the internet. Furthermore, they themselves can create other job opportunities for others.
A low latency quaternion-based web transmission system for augmented reality applications
Authors: Ijaz Umer , Butt Arslan Dawood , Khalid Muhammad Husnain , Anwar Muhammad Fraz , Malik Muhammad 
Published: January 2021

This work deals with the development and testing of a low latency Animation Transmission Technology (ATT) for augmented reality applications. This web-based transmission system based on AutoBahn Pyhton web server and WebSocket LibrarY (WSLAY) integrated clients has been studied to reduce packet header size and to simultaneously allow a large number of Users to interact with each other. The transmission system in the proposed system architecture allows motion sensor’s acquisition software to easily send compressed 3D quaternion-based data from transmitter to the rendering softwares at receiver side to generate real time 3D animation on an avatar. Furthermore, effects of lossy compression of quaternion data and server limitation have also been considered. Initial simulation test results with the Python server alongside WSLAY integrated clients with virtual motion sensors have been presented in this work. It has been evaluated that the network delay (ND) has a huge improvement from more than 300 ms to less than 25 ms at 100 Hz sensor sampling rate once lossy compression of 3D quaternion data is implemented. Furthermore, the effect of motion sensor sampling frequency and broadcast server limitation on maximum number of simultaneous users/sensors is also described in this work.