bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peculiarities of industrial nature management in the conditions of modern decentralization
Authors: Nazaruk Mykola , Halianta Lidiia 
Published: November 2021

The aim of the study was to determine the features of industrial development in modern decentralization.
Materials and methods. This study is based on the study of literature sources that characterize the problems of industrial nature management, features of development and operation, geospatial features of industry. The most well-known literary sources are analyzed, namely monographs, reporting materials, articles, reports concerning the problems of industrial nature management in the conditions of modern decentralization.
Results. Decentralization contributes to the development of the economy, as the authorities respond more quickly to the demands and needs of society. Decentralization processes are improving the so-called investment climate, resulting in economic growth. That is why it is important to consider the factors influencing the development of industry in today's decentralization. We highlight the political and legal, economic, socio-demographic, technological factors of industrial development. On their example, we will consider features of development of the industry in the conditions of modern decentralization.
Conclusion. The analysis of development factors and structural transformations in industry has revealed a number of sharp contradictions that create many risks for the existence of the industry itself, as well as the economy and social sphere of the country. This poses a number of serious challenges to the country to overcome such contradictions as: the inconsistency of the general trend of the industry with the development of world industry in structural and technological terms; continuation of structural and organizational degradation of production with preservation of its export-raw material orientation and corresponding dependence on external conditions; increasing technological simplification and primitivization of production; inconsistency of domestic production with the needs of the population; the progressive decline of processing industries, including high-tech and fund-generating, for the domestic consumer market; high depreciation of fixed assets and unattractive investment of the industry, including for foreign investors; remoteness of the financial sector from servicing long-term investment needs of production; "Conservative" distribution of investment resources; lack of a mechanism for redistribution of investment resources in favor of promising industries. The identified contradictions and the resulting risks to the further functioning of the industry must be resolved as soon as possible for progressive changes and industrial development in the future.
Towards to the mind-body problem
Authors: Skowron Adam , Sytnik-Czetwertyński Janusz 
Published: November 2021

The mind-body problem is one of the most difficult challenges of modern science. An
interesting attempt at providing a reductionist model of reality was made in the 18th century
by Ruder Josip Bošković. The attractiveness of this model lies in the fact that it does not
readily fit into any of the above categorizations. Although frequently associated with the third
- a fact that laid it open to violent criticism, causing the philosopher serious trouble - it stands
apart as an independent theory. For, according to Bošković, reality is neither material nor
spiritual. Nor is it a union of both of these orders.
Epidemiologia raka jelita grubego (C18-C21) w Polsce
Authors: Jaroszyńska Zuzanna , Wiśniewska Katarzyna 
Published: November 2021

Wprowadzenie i cel: Rak jelita grubego (C18-C21) jest jednym z najczęściej występujących nowotworów złośliwych w polskiej populacji. Celem niniejszej pracy była analiza sytuacji epidemiologicznej raka jelita grubego w Polsce, której dokonano na podstawie danych epidemiologicznych, opublikowanych przez Krajowy Rejestr Nowotworów, Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie – Państwowy Instytut Badawczy oraz ECIS – European Cancer Information System.
Opis stanu wiedzy: Rak jelita grubego był w Polsce w 2018 roku trzecim co do częstości występowania nowotworem złośliwym, na który zapadają mężczyźni i drugim najczęściej diagnozowanym nowotworem złośliwym u kobiet. W tym samym roku w Polsce zarejestrowano niemal 12,5 tys. zgonów z powodu raka jelita grubego. Nowotwór ten stanowił wówczas drugą wśród mężczyzn i trzecią wśród kobiet najczęstszą przyczynę zgonów z powodu nowotworów złośliwych. Pod względem wskaźników 5 letnich przeżyć dla pacjentów chorych na raka jelita grubego, mimo obserwowanej na przestrzeni lat poprawy, Polska wciąż zajmuje jedno z ostatnich miejsc w Europie.
Wnioski: Rak jelita grubego, ze względu na rozpowszechnienie, stanowi poważny problem zdrowotny polskiego społeczeństwa. Skala zachorowań i zgonów z powodu tych nowotworów, mimo rozwijającej się wiedzy medycznej oraz poprawy dostępności do nowoczesnych metod diagnostycznych i terapeutycznych, wciąż jest niepokojąca. Istnieje pilna potrzeba zintensyfikowania działań w obszarze profilaktyki przeciwnowotworowej na poziomie populacyjnym.
New aspects of pedagogical activity in the distant form of pathological physiology teaching to medical university students
Authors: Vastyanov R. , Yermuraki P. , Stoyanov A. , Tiron O. , Beseda Ya. , Ostapenko I. , Dobrovolsky V. , Lapshin D. , Stecenko A. 
Published: November 2021

Distance learning (DL) is a completely new and unique form of education, which got forced to switch to by the current pandemic of coronavirus disease.
Note that until now, distance learning technologies have been used at the department of general and clinical pathological physiology and some other departments of the Odessa National Medical University (ONMedU).
The aim of this analytical article is to analyze the efficacy of ONMedU General and Clinical Pathological Physiology Department staff during the one and a half year period of the coronavirus infection pandemic with an accent to psychological approach to students modified teaching. The urgent need of time and the primary desire to protect students and their own lives during 2020-2021 requires us to improve our own pedagogical approaches in the further on-line teaching of students.
We see success in systematic methodological work with students, the implementation of which will make it possible to evoke and increase their motivation to study histology. The importance of this methodological technique, supported in the senior years of medical universities by the integration of teaching theoretical and clinical disciplines, the approximation of teaching to specific clinical cases will help optimize the assimilation of morphological knowledge by students at least and, undoubtedly, in the near future will lead to a better assimilation of clinical disciplines.
In connection with the ideas of individualized and developmental learning, the use of psychological capabilities of learning tools in the virtual environment brings both pedagogy and psychology to a new level of understanding the mediation of mental, creative, communicative and executive learning and learning activities.
The use of distance learning helps the students to acquire skills of independent work, creates comfortable conditions for creativity, increases the creative and intellectual potential of the student through self-organization, the ability to interact with computer technology and make responsible decisions, creates favorable conditions for individual creative expression in the process of learning, for the development of the student's personality.
The authors are convinced that the optimization and improvement of the educational process in medical universities is to draw students' attention to the problems that the medical community is dealing with on a daily basis today.
Long-term consequences of traumatic brain injuries with ice-hockey players
Authors: Sekretnyi Volodymyr , Nekhanevych Oleh 
Published: November 2021

Introduction
Significant part of sports related concussions (SRC) are below the level of clinical diagnosis of SRC or are unnoticed. The most severe cumulative consequence of SRC is chronic traumatic encephalopathy (CTE). The study of a wide range of clinical manifestations of CTE plays an important role.
Purpose
To establish long-term cognitive consequences of TBI in ice hockey players.
Material and methods
Retrospectively, we tested retired 20 ice hockey players. All athletes completed a questionnaire with their team doctor, which included: passport part, sports history, history of SRC, a mini mental scale evaluation (MMSE) and «the clock drawing test».
Results
The results of the analysis showed a statistically significant decrease in the value of MMSE with an increase in SRC more than 1 during a sports career. Thus, in the group with 1 SRC the value of MMSE was 28.7 (1.38) points, while in the group with 2 or more SMS it was equal to 26.7 (1.15) points (p <0.05). MMSE goalkeepers scored 26.6 (0.6) points, strikers – 27.8 (0.4) points, defenders – 28.2 (0.7) points (p<0.05). The fact of hospitalization indicates clinically significant severity of a history of SRC. Having retrospectively collected data on hospitalization of hockey players after SRC, there was also a decrease in the value of MMSE in those with a history of hospitalization. Thus, in the group of people with hospitalization MMSE was 27.1 (1.39) points, without hospitalization – 27.9 (1.7). No statistically relationship between age and severity of cognitive impairment was found. Significant statistic connection (n = 20, correlation coefficient rs = – 0.40; p<0.05) has been found between the number of SRC and the indicator and MMSE test and between number of SRC and «the clock drawing test» (n = 20, correlation coefficient rs = – 0.10; p <0.05).
Conclusions
Our study has outlined connection between cognitive impairment in ice-hockey players and SRC.
Scalable Optimization Methods for Incorporating Spatiotemporal Fractionation into Intensity-Modulated Radiotherapy Planning
Authors: Adibi Ali , Salari Ehsan 
Published: November 2021

It has been recently shown that an additional therapeutic gain may be achieved if a radiotherapy plan is altered over the treatment course using a new treatment paradigm referred to in the literature as spatiotemporal fractionation. Because of the nonconvex and large-scale nature of the corresponding treatment plan optimization problem, the extent of the potential therapeutic gain that may be achieved from spatiotemporal fractionation has been investigated using stylized cancer cases to circumvent the arising computational challenges. This research aims at developing scalable optimization methods to obtain high-quality spatiotemporally fractionated plans with optimality bounds for clinical cancer cases. In particular, the treatment-planning problem is formulated as a quadratically constrained quadratic program and is solved to local optimality using a constraint-generation approach, in which each subproblem is solved using sequential linear/quadratic programming methods. To obtain optimality bounds, cutting-plane and column-generation methods are combined to solve the Lagrangian relaxation of the formulation. The performance of the developed methods are tested on deidentified clinical liver and prostate cancer cases. Results show that the proposed method is capable of achieving local-optimal spatiotemporally fractionated plans with an optimality gap of around 10%–12% for cancer cases tested in this study.Summary of Contribution: The design of spatiotemporally fractionated radiotherapy plans for clinical cancer cases gives rise to a class of nonconvex and large-scale quadratically constrained quadratic programming (QCQP) problems, the solution of which requires the development of efficient models and solution methods. To address the computational challenges posed by the large-scale and nonconvex nature of the problem, we employ large-scale optimization techniques to develop scalable solution methods that find local-optimal solutions along with optimality bounds. We test the performance of the proposed methods on deidentified clinical cancer cases. The proposed methods in this study can, in principle, be applied to solve other QCQP formulations, which commonly arise in several application domains, including graph theory, power systems, and signal processing.
Hedging on the Hill: Does Political Hedging Reduce Firm Risk?
Authors: Christensen Dane M. , Jin Hengda , Sridharan Suhas A. , Wellman Laura A. 
Published: November 2021

We examine whether firms’ political hedging activities are effective at mitigating political risk. Focusing on the risk induced by partisan politics, we measure political hedging as the degree to which firms’ political connections are balanced across Republican and Democratic candidates. We find that greater political hedging is associated with reduced stock return volatility, particularly during periods of higher policy uncertainty. Similarly, greater political hedging is associated with reduced crash risk, investment volatility, and earnings volatility. Moreover, the reduction in earnings volatility appears to relate to both a firm’s taxes and its operating activities, as we find that greater political hedging is associated with reduced cash effective tax rate volatility and pretax income volatility. We further find investors are better able to anticipate future earnings for firms that engage in political hedging, suggesting that political hedging helps improve firms’ information environments. Lastly, we perform an event study using President Obama’s Clean Power Plan. We find that on the days this policy proposal was debated in Congress, energy and utility firms experienced heightened intraday return volatility (relative to other firms and nonevent days). However, this heightened volatility is mitigated for energy and utility firms that are more politically hedged. Overall, we conclude that political hedging is an effective risk management tool that helps mitigate firm risk. This paper was accepted by Suraj Srinivasan, accounting.
Coping with Digital Extortion: An Experimental Study of Benefit Appeals and Normative Appeals
Authors: Chen Kay-Yut , Wang Jingguo , Lang Yan 
Published: November 2021

Digital extortion has emerged as a significant threat to organizations that rely on information technologies for their operations. Using human subject experimentation, we study the effectiveness of message appeals in encouraging defenders to adopt two mitigation strategies, investment in security and refusal to pay ransoms, to digital extortion threats. We explore two types of appeals, benefit and normative, for this purpose. We find that the decisions of the defenders (representing any organization that can be a potential victim) deviate from the predictions of game theory. However, given the strategic interactions between the defenders and the attacker as well as noisy decision-making behaviors, it is challenging to untangle the influence of the appeals on the defenders. We develop a structural model based on the quantal response equilibrium framework to measure how message appeals change the defenders’ utilities of investment and payment refusal. Although the interventions may be successful in increasing the utilities of investment and/or payment refusal, their impacts on investment rate and payment rate are mitigated by the attacker reducing ransoms. Thus, it is challenging for an intervention to significantly boost a community’s investment rate or to suppress the ransom payment rate. We characterize how security outcomes of a community (including expected ransom, attack rate, investment rate, and payment rate) vary with the defenders’ utilities of investment and pay refusal. This paper was accepted by Chris Forman, information systems.
Pharmacist involved education program in a multidisciplinary team for oral mucositis: Its impact in head-and-neck cancer patients
Authors: Yoshida Kensuke , Kodama Yasumitsu , Tanaka Yusuke , Pak Kyongsun , Soga Marie , Toyama Akira , Katsura Kouji , Takagi Ritsuo 
Published: November 2021

Objectives
This retrospective study examined how a pharmacist-involved education program in a multidisciplinary team (PEMT) for oral mucositis (OM) affected head-and-neck cancer (HNC) patients receiving concurrent chemoradiotherapy (CCRT).

Materials and methods
Total samples data of 53 patients during the stipulated timeframe were retrospectively collected from electronic medical records from February 2017 to January 2019. We compared the presence/absence of OM (OM: yes/no) between patients with and without PEMT (PEMT: yes/no) as the primary endpoint and OM severity as the secondary endpoint. The following information was surveyed: age, gender, weight loss, steroid or immunosuppressant use, hematological values (albumin, white blood cell count, blood platelets, and neutrophils), cancer grade, primary cancer site, type and use of mouthwash and moisturizer, opioid use (yes/no, days until the start of opioid use, and dose, switch to tape), and length of hospital day (LOD). The two groups were compared using Fisher’s exact test for qualitative data and the Mann-Whitney U test for quantitative data, and a significance level of p<0.05 was set.

Results
The group managed by PEMT had significantly lower weight loss and a significantly lower incidence of local anesthetic and opioid use and switch to tape compared with the group not managed by PEMT (p<0.05). The two groups showed no significant difference in OM (yes/no) or OM severity. The PEMT group had significantly shorter LOD at 57 (53–64) days compared with the non-PEMT group at 63.5 (57–68) days (p<0.05).

Conclusions
Our results showed that PEMT did not improve OM (yes/no) or OM severity in HNC patients undergoing CCRT. However, the PEMT group had a lower incidence of grades 3 and 4 OM than the non-PEMT group, although not significantly. In addition, PEMT contributed to oral pain relief and the lowering of the risk for OM by reduction in weight loss.
Clinicopathologic and prognostic implications of Golgi Phosphoprotein 3 in colorectal cancer: A meta-analysis
Authors: Wang Tao , Fei Jiandong , Nie Shuangfa 
Published: November 2021

Background
Golgi Phosphoprotein 3 (GOLPH3) has been implicated in the development of colorectal cancer (CRC). Nevertheless, the clinicopathological and prognostic roles of GOLPH3 in CRC remain undefined. We thus did a meta-analysis to assess GOLPH3 association with the clinicopathological characteristics of patients and evaluate the prognostic significance of GOLPH3 in CRC.

Methods
An electronic search for relevant articles was conducted in the PubMed, Cochrane Library, Web of Science, Medline, Embase, CNKI, and WanFang databases. Two independent reviewers searched all the literature and finished the data extraction and quality assessment. Odds ratio (OR) or hazard ratio (HR) with 95% confidence interval (CI) were used to assess estimates. Stata software (version12.0) was employed to analyze the data.

Results
A total of 8 published studies were eligible (N = 723 participants). Meta-analysis revealed that GOLPH3 was found to be highly expressed in tumor tissues compared to that of adjacent colorectal tissues (OR, 2.63), and overexpression of GOLPH3 had significant relationship with advanced clinical stage (OR, 3.42). GOLPH3 expression was not correlated with gender (OR, 0.89), age (OR, 0.95), positive lymphatic metastasis (OR, 1.27), tumor size (OR, 1.12), poor differentiation of tumor (OR, 0.56) or T stage (OR, 0.70). Moreover, GOLPH3 overexpression was not associated with worse overall survival (OS) (HR = 1.14, 95% CI: 0.42–1.86, P>0.05) and disease-free survival (DFS) (HR = 0.80, 95% CI:-0.26–1.86, P>0.05).

Conclusions
GOLPH3 overexpression is correlated with tumor stage, which is an adverse clinicopathological characteristic of CRC. But, GOLPH3 can not serve as a useful biomarker in evaluating the progression of CRC.
Genesis and Exodus as Conceptually Independent, Competing Origin Myths?
Authors: Hong Koog P. 
Published: November 2021

Abstract
Against Konrad Schmid’s thesis that the pre-P ancestral and Exodus traditions existed as competing origin myths that were conceptually independent from each other, this article argues that this conceptual independence is difficult to prove in the context of the ancient Israelites’ oral-written culture. Moreover, societal negotiation about the past should not be misconstrued as a sign of traditions’ conceptual independence. Competition between origin stories, or selective emphasis on one story over another, does not indicate their conceptual independence.
Purging the Evil from Israel: The Function of the Deuteronomic Formula in Judg 20:13
Authors: Ber Viktor 
Published: November 2021

Abstract
This article argues for the importance of the purging formula in Judg 20:13. In the Deuteronomic Code, this formula provides the motivation for capital punishment in two areas relevant to the Judges narrative: first, apostasy and incitement to it, and, second, the perversion of Deuteronomic legal procedures. This study argues that both motifs are present in and important to Judges’ rendering of the Sodom-like outrage in Gibeah. The first is obvious. With regard to the second, the article argues that the Israelites err in their investigation of the case, and therefore their decisions and subsequent action lead to more violence and confusion. It is further argued that the triple oracular inquiry of YHWH in Judg 20:18–28 is presented as an inadequate substitute for proper forensic adjudication; it therefore does not lead to the establishment of order and justice.
Can remote work during COVID-19 pandemic strengthen the link between workload and workaholism?
Authors: Morkevičiūtė Modesta , Endriulaitienė Auksė 
Published: November 2021

The aim of the present study was to investigate the role of the way of doing work for the relationship between workload and workaholism during COVID-19 pandemic. A total of 668 employees working in different Lithuanian organizations participated in a study. A sample included employees who worked in the workplace (n = 331), as well as those who worked completely from home (n = 337). The levels of workaholism were measured using DUWAS-10 (Schaufeli et al., 2009). Workload was assessed with the help of the Quantitative Workload Inventory (QWI; Spector & Jex, 1998). It was revealed in a study that the higher levels of workload experienced by employees were related to the increased workaholism. It was further found that the positive relationship between workload and worka­holism was stronger in the group of complete remote workers. Overall, the findings support the idea that remote work is an important variable increasing a risk for workaholism especially for those employees who experience a heavy workload. Therefore, the ways of doing work must be considered when addressing well-being of employees.