bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS KUALITAS PRODUK KORAN MENGGUNAKAN METODE SIX SIGMA DAN FAILURE MODE AND EFFECT ANALYSIS (FMEA) DI PT. XYZ BALIKPAPAN
Authors: Sepriandini Frizkia , Ngatilah Yustina 
Published: July 2021

PT. XYZ adalah sebuah perusahaan yang bergerak di bidang percetakan dan mempunyai beberapa anak cabang di seluruh wilayah Kalimantan Timur. Salah satu hasil produksi perusahaan ini adalah surat kabar harian atau koran. Adapun jumlah rata-rata produksi tahun 2019 adalah 908.489 eksemplar dan jumlah rata-rata produk cacat tahun 2019 sebesar 27.106 eksemplar. Adapun tujuan penelitian ini adalah mengetahui persentase kualitas dan nilai sigma, faktor-faktor penyebab kecacatan serta dampak yang ditimbulkan, dan memberikan usulan perbaikan kualitas produk. Metode yang diusulkan adalah Six Sigma dan Failure Mode and Effect Analysis (FMEA). Adapun tahapan Six Sigma adalah define, measure, analyze, improve, dan control (DMAIC). Untuk metode Failure Modes and Effect Analysis (FMEA) digunakan pada tahap improve, yaitu untuk menganalisis akar penyebab tingginya kecacatan serta memberikan usulan perbaikan. Hasil dari penelitian ini menunjukkan bahwa perusahaan memiliki total jumlah kecacatan koran sebesar 198.606 eksemplar yang terdiri lembab, warna kabur, berbayang, dan tidak simetris. Saat ini, perusahaan berada di level 3,97 sigma sehingga perlu dilakukan perbaikan yang dilakukan untuk mencapai level 6 sigma. Dengan meenggunakan metode FMEA diketahui bahwa kecacatan yang mendominasi adalah cacat warna kabur. Adapun rekomendasi perbaikannya adalah mengganti tinta dengan tinta yang memiliki kepekatan lebih rendah, melakukan pengecekkan kembali sebelum menyalakan mesin dan memperketat pengawasan proses cetak koran, menetapkan aturan dalam standar pengisian tinta, dan memberi pengarahan pada operator mengenai standar pengisian tinta.
ANALISIS PERANCANGAN ULANG TATA LETAK LANTAI PRODUKSI MENGGUNAKAN METODE AlGO-RITMA CRAFT DI PT. XYZ
Authors: Ferinanda Shafira Sausan , Rusindiyanto Rusindiyanto 
Published: July 2021

Perancangan tata letak fasilitas lantai produksi haruslah direncanakan dengan sebaik mungkin agar tercipta tata letak fasilitas yang efisien dan optimal dengan panjang lintasan material handling yang pendek. PT. XYZ merupakan salah satu perusahaan manufaktur atau pabrik yang memproduksi berbagai jenis sepatu. Layout lantai produksi yang sekarang diterapkan dirasa masih belum optimal karena jarak antar tiap stasiun cukup jauh maka menimbulkan biaya material handling yang sedikit lebih besar serta apabila jarak antar stasiun memiliki jarak yang cukup jauh maka akan menghabiskan lebih banyak waktu. Sehingga perlu dilakukan perancangan ulang tata letak lantai produksi. Penyelesaian masalah dengan menggunakan metode algoritma, algoritma yang digunakan yaitu algoritma CRAFT (Computerizad Relative Allocation of Facilities Techniques). CRAFT merupakan sebuah algoritma yang mencari perancangan optimal dengan melakukan perbaikan tata letak secara bertahap. Berdasarkan permasalahan diatas maka dibuatlah penelitian yang bertujuan untuk meminimumkan jarak perpindahan antar stasiun kerja dan meminimumkan ongkos material handling dengan perancangan ulang tata letak lantai produksi yang baik dengan menggunakan metode Algortma Craft (Computerized Relative Allocation of Facilities Techniques) di PT. XYZ . Hasil penelitian ini adalah pada layout awal didapatkan total jarak sebedar 53,5 meter sedangkan untuk hasil akhir total jarak setelah pengolahan data adalah 46 meter dengan selisih 7,5 meter dari layout awal. Pada layout awal didapatkan total cost material handling sebesar Rp 646.900,00 untuk satu kali putaran proses produksi sedangakan pada layout akhir didapatka hasil total cost adalah Rp. 449.392,40 dimana terdapat pengurangan Rp 197.507,60.
Kata Kunci: Tata Letak, Material Handling, CRAFT
Sağlık Okuryazarlığının Diyet Kalitesine Etkisi
Authors: Yılmaz Müge , Yaşar Fırat Yağmur , Gül Fatma Hazan , Atuk Kahraman Tutku 
Published: July 2021

Amaç: Bu kesitsel araştırma, üniversite öğrencilerinin sağlık okuryazarlığı düzeyinin diyet kalitesine etkisini belirlemek amacıyla yürütülmüştür.
Bireyler ve yöntem: Çalışmaya Erciyes Üniversitesi Sağlık Bilimleri Fakültesi Beslenme ve Diyetetik Bölümü (BD), Turizm Fakültesi (TF) ve Spor Bilimleri Fakültesindeki (SB) 580 gönüllü öğrenci dâhil edilmiştir. Sağlık okuryazarlığı “En Yeni Yaşamsal Bulgu Testiyle (NVS)”, diyet kalitesi “Sağlıklı Yeme İndeksi-2015 (SYİ-2105)”le saptanmıştır. Veriler yüz yüze görüşme yöntemiyle toplanmış, antropometrik ölçümler yapılmıştır. p<0.05 değeri istatistiksel olarak anlamlı kabul edilmiştir.
Bulgular: Yeterli sağlık okuryazarlığı olanların oranı sırasıyla en yüksek BD (%99.2), daha sonra SB (%53.2), en az TF (%31.2) öğrencilerinindir (p<0.001). Sağlık okuryazarlığı düzeyinin TF (2.59±1.97) ve SB (3.48±1.87) öğrencilerinin sınırlı, BD öğrencilerinin (5.55±0.68) yeterli olduğu saptanmıştır. Sağlık okuryazarlığı düzeyi yeterli olan öğrencilerin SYİ-2015 puanı (56.30±9.73), sınırlı (54.26±9.61) ve yüksek olasılıklı sınırlı (53.77±9.52) olanlardan anlamlı olarak daha yüksektir (p=0.037) Sağlık okuryazarlığı düzeyi ile diyet kalitesi arasında pozitif yönlü zayıf anlamlı korelasyon saptanmıştır (rho=0.123, p=0.003). Bireylerin bel çevresi ve bel/kalça oranıyla NVS puanı, bel/kalça oranıyla SYİ-2015 puanı arasında negatif yönlü zayıf korelasyon bulunmuştur (p<0.05).
Sonuç: Sağlık okuryazarlığı düzeyindeki artış diyetin kalitesini olumlu yönde etkilemekte, daha sağlıklı beslenme alışkanlığına sahip olunduğunu göstermektedir. BD öğrencilerinin sağlık okuryazarlığı düzeyinin ve diyet kalitelerinin SB ve TF öğrencilerine göre yüksek olması beklenen bir sonuçtur. Ancak BD öğrencileri için de SYİ-2015 puanı beklenenin altındadır ve diyetlerinin kalitelilerinin iyileştirilmesi gerekmektedir. Beslenmeyle yakından ilişkili olan TF ve SB fakültelerinin eğitim müfredatlarındaki beslenme ile ilgili derslerin sayısı ve saatlerinin artırılması önerilir.
The Effect of Picture-Cued Task towards Students’ Motivation in Learning Writing
Authors: Astuti Warih , Suadiyatno Taufik 
Published: July 2021

This study intended to find out the effect of Picture-Cued Task towards Students’ Motivation in Learning Writing at SMPN 3 Lingsar in the academic year 2018/2019. The population of the second grade of SMPN 3 Lingsar was 120 students and the researchers took VIII-B class as an Experimental group and VIII-D as a Control group. The Experimental group was treated by Picture-Cued Task and the Control group was treated by Mind Mapping. The instruments that were used to collect the data were tests and questionnaires. The data was analyzed by using Quantitative research and the way researchers analyzed the data was by; scoring, percentile meanings, and impacts. The Quantitative Data showed that the students were able to arrange their grammar and vocabularies well when making short sentences through Picture-Cued Task. Those students were enthusiastically joined the class even though they were wondering what to do with pictures. In Quantitative Data, the researchers found; Mean = 26,07, Median = 25, Mode = 20 and Standard Deviation = 6,434. The t-test score was 6,392 and the t-table was 1,67 in significance level 0,05 with the degree of freedom 54, therefore, the score of the t-test is higher than the t-table. Based on the data finding and discussion, it can be concluded that the use of Picture-Cued Task has a positive effect to motivate students in learning writing.
Uso de plantas medicinais por indivíduos de uma comunidade do Acre
Authors: Costa Ruth  Silva Lima da , Tavares Vanessa Victoria Alnert Vieira , Dourado Eduardo Souza , Costa Vanessa Holanda de Souza Ribeiro da , Lameira Yara Costa , Américo Priscila Santos , Santos Raquel Rodrigues dos 
Published: July 2021

O objetivo foi demonstar o uso de plantas medicinais por indivíduos de uma comunidade do Acre. Trata-se de um estudo descritivo e exploratório, de abordagem qualitativa, elaborado a partir de entrevistas realizadas junto a 21 indivíduos, de ambos os sexos, residentes nas adjacências de um bairro periférico do município de Rio Branco - Acre, em cuja localidade se encontra uma horta comunitária com o cultivo de plantas medicinais. A população participante do estudo, pertencia em sua maioria ao sexo feminino, dentro da faixa etária de 54 a 80 anos e faziam uso de plantas medicinais frequentemente, além de as indicar para familiares e amigos. A maioria aprendeu sobre o uso das plantas com as mães e as avós. Cerca de 32 espécies foram citadas como utilizadas para os mais variados tratamentos, sendo que a maioria utilizava as ervas em forma de chá. Eles expressaram que as práticas do uso de fitoterápicos podem colaborar com a melhora do estado de saúde de quem faz uso delas e que acreditavam no poder de cura das mesmas, pois tiveram experiências próprias a partir do seu uso. A população estudada, utiliza as plantas medicinais, embasadas apenas em seu conhecimento popular tradicional e na indicação de outros, o que evidencia a necessidade da realização de pesquisas para o melhor conhecimento e difusão de informações das propriedades terapêuticas e tóxicas afim de se evitar futuras complicações.
Prevalência de disfunções sexuais no puerpério de parto cesáreo
Authors: Baratella Thayna Maria Praia , Quiros Ana Carolina Silva , Veras Maria Eduarda Siqueira , Alves Jamile Maria Souza , Silva Thaynan Santos da , Barros Marina de Lima Neves , Uchôa Erica Patrícia Borba Lira , Carvalho Valéria Conceição Passos de 
Published: July 2021

Objetivo: Descrever a prevalência de disfunções sexuais no puerpério de parto Cesário. Metodologia: Estudo do tipo observacional descritivo, o tamanho da amostra foi de 30 puérperas. Sendo desenvolvido de forma digital, através de um formulário criado no Google Forms de outubro de 2020 a abril de 2021. A primeira etapa contou com o preenchimento dos dados sociodemográficos no formulário e em seguida aplicação do Female Sexual Function Index (FSFI), um autorrelato com 19 itens que abrange seis domínios sexuais (desejo, excitação, lubrificação, orgasmo, satisfação e dor), nas últimas quatro semanas, a paciente seleciona uma das respostas que mais lhe representa, a alternativa 0 indica que não teve relação sexual e as outras variam de 1 a 5. O somatório final reúne as respostas de todos os domínios. A análise estatística foi descritiva. Resultados: Dentre as voluntárias, 80% da população possui faixa etária entre 19-29 anos de idade e 43,3% das mulheres são casadas, 53,3% das mulheres concluíram o ensino superior. 70% da amostra esteve grávida apenas 1 vez e 76,6% realizaram apenas 1 cesárea até o momento da pesquisa. Em relação ao desejo, 36,7% das mulheres relataram sentir desejo ou interesse sexual poucas vezes. Quando se questiona sobre a satisfação sexual, 53,3% relataram estar muito satisfeitas com a intensidade de intimidade emocional com seu parceiro. Conclusão: O presente estudo evidenciou que as mulheres participantes da pesquisa que estavam no puerpério de parto Cesáreo não apresentaram uma DSF e sim uma alteração moderada na atividade sexual.
Game Studies, Next Level? Nuevos horizontes para una disciplina emergente
Authors: Gómez-García Salvador , De la Hera Teresa , Cuadrado-Alvarado Alfonso 
Published: July 2021

Tras fraguarse durante las últimas décadas, la disciplina de Game Studies ha concluido su fundamentación teórica y metodológica y ha desarrollado un interés institucional por parte de académicos de todo el mundo. Este número temático de la revista index.comunicación presenta una recopilación de estudios relacionados con la disciplina de Game Studies, llevados a cabo en el ámbito español y centrados en la exploración de líneas de futuro de una disciplina heterogénea y transversal. En concreto, se pone el foco en rasgos de las particularidades narrativas del juego, su potencial persuasivo y su influencia social. El principal objetivo de este especial es consolidar un punto de reflexión de la investigación de presente y de futuro sobre los Game Studies.
Supercritical CO2 Synthesis of Freestanding Se1-xSx Foamy Cathodes for High-Performance Li-Se1-xSx Battery
Authors: Lu Chengwei , Fang Ruyi , Wang Kun , Xiao Zhen , kumar G. Gnana , Gan Yongping , He Xinping , Huang Hui , Zhang Wenkui , Xia Yang 
Published: July 2021

Selenium-sulfur solid solutions (Se1-xSx) are considered to be a new class of promising cathodic materials for high-performance rechargeable lithium batteries owing to their superior electric conductivity than S and higher theoretical specific capacity than Se. In this work, high-performance Li-Se1-xSx batteries employed freestanding cathodes by encapsulating Se1-xSx in a N-doped carbon framework with three-dimensional (3D) interconnected porous structure (NC@SWCNTs) are proposed. Se1-xSx is uniformly dispersed in 3D porous carbon matrix with the assistance of supercritical CO2 (SC-CO2) technique. Impressively, NC@SWCNTs host not only provides spatial confinement for Se1-xSx and efficient physical/chemical adsorption of intermediates, but also offers a highly conductive framework to facilitate ion/electron transport. More importantly, the Se/S ratio of Se1-xSx plays an important role on the electrochemical performance of Li- Se1-xSx batteries. Benefiting from the rationally designed structure and chemical composition, NC@SWCNTs@Se0.2S0.8 cathode exhibits excellent cyclic stability (632 mA h g−1 at 200 cycle at 0.2 A g−1) and superior rate capability (415 mA h g−1 at 2.0 A g−1) in carbonate-based electrolyte. This novel NC@SWCNTs@Se0.2S0.8 cathode not only introduces a new strategy to design high-performance cathodes, but also provides a new approach to fabricate freestanding cathodes towards practical applications of high-energy-density rechargeable batteries.
Perfluoroalkyl Substance Exposure and the BDNF Pathway in the Placental Trophoblast
Authors: Marchese Melissa J. , Li Shuman , Liu Bin , Zhang Jun J. , Feng Liping 
Published: July 2021

BackgroundPer- and polyfluoroalkyl substances (PFAS) are persistent organic pollutants that have become globally ubiquitous in humans and the environment. In utero PFAS exposure is associated with neurodevelopmental effects; however, the mechanism is poorly understood. Brain-derived neurotrophic factor (BDNF) signaling is critical to fetal neurodevelopment during pregnancy and maintains important regulatory roles later in life. This study aims to characterize placental BDNF signaling and investigate whether PFAS exposure disrupts the signaling pathway in placental trophoblast cells.MethodsThe expression and localization of BDNF receptors–p75NTR and TrkB–in first trimester and term human placentas and trophoblast cells were investigated by immunofluorescence staining. To assess the effects of PFAS exposure on the BDNF pathway, BeWo cells were treated with PFAS mixtures that mimicked blood levels in a highly exposed population and major PFAS compounds in the mixture at 0.01, 0.1, 1, and 10 µM concentrations. Changes in pro-BDNF levels and phosphorylation of TrkB receptors were examined by Western blot.ResultsIn first trimester human placentas, TrkB and p75NTR receptors were primarily localized to syncytiotrophoblast and cytotrophoblast cells. At term, TrkB and p75NTR receptors were primarily observed in the placental villous stroma. TrkB receptor staining in trophoblasts was reduced at term, while p75NTR receptor staining was negative. TrkB receptors were confined to the nuclear and perinuclear spaces, and phosphorylation occurred at the Tyr816 residue in BeWo cells. Exposure to PFOS, PFOA, PFBS, and the six-PFAS mixture did not significantly affect BDNF levels or activation (phosphorylation) of TrkB. Treating cells with 1 μM and 10 μM of PFNA resulted in increased TrkB phosphorylation compared to unexposed controls, but BDNF levels were unchanged.ConclusionsBDNF receptors are present in different regions of human placental villi, indicating diverse functions of BDNF signaling in placental development. Our findings suggest that the BDNF pathway in placental trophoblast cells is not disrupted by exposures to PFOS, PFOA, PFBS, and a PFAS mixture, but may be affected by PFNA exposures. Further investigation is needed on how PFAS affects other critical signaling pathways during fetal neurodevelopment.
Predictive Value of Free Triiodothyronine to Free Thyroxine Ratio in Euthyroid Patients With Myocardial Infarction With Nonobstructive Coronary Arteries
Authors: Gao Side , Ma Wenjian , Huang Sizhuang , Lin Xuze , Yu Mengyue 
Published: July 2021

BackgroundThyroid function is closely involved in cardiovascular diseases. The free triiodothyronine (fT3) to free thyroxine (fT4) ratio has been reported as a risk factor for coronary artery disease, but its prognostic value in euthyroid patients with myocardial infarction with nonobstructive coronary arteries (MINOCA) remains unclear.MethodsA total of 1162 euthyroid patients with MINOCA were enrolled and divided according to decreased tertiles of fT3/fT4 ratio. The study endpoint was major adverse cardiovascular events (MACE), including all-cause death, nonfatal MI, nonfatal stroke, revascularization, and hospitalization for unstable angina or heart failure. Kaplan-Meier, Cox regression, and receiver-operating characteristic analyses were performed.ResultsPatients with lower fT3/fT4 tertile levels had a significantly higher incidence of MACE (10.0%, 13.9%, 18.2%; p=0.005) over the median follow-up of 41.7 months. The risk of MACE increased with the decreasing fT3/fT4 tertiles even after multivariate adjustment (tertile1 as reference, tertile2: HR 1.58, 95% CI: 1.05-2.39, p=0.030; tertile3: HR 2.06, 95% CI: 1.17-3.11, p=0.006). Lower level of fT3/fT4 ratio remained a robust predictor of MACE in overall (HR 1.64, 95% CI: 1.18-2.29, p=0.003) and in subgroups. When adding fT3/fT4 ratio [area under the curve (AUC) 0.61] into the thrombolysis in myocardial infarction (TIMI) risk score (AUC 0.69), the combined model (AUC 0.74) yielded a significant improvement in discrimination for MACE (ΔAUC 0.05, p=0.023).ConclusionsLow level of fT3/fT4 ratio was strongly associated with a poor prognosis in euthyroid patients with MINOCA. Routine assessment of fT3/fT4 ratio may facilitate risk stratification in this specific population.
The Importance of Metabolism for Immune Homeostasis in Allergic Diseases
Authors: Rodriguez-Coira Juan , Villaseñor Alma , Izquierdo Elena , Huang Mengting , Barker-Tejeda Tomás Clive , Radzikowska Urszula , Sokolowska Milena , Barber Domingo 
Published: July 2021

There is increasing evidence that the metabolic status of T cells and macrophages is associated with severe phenotypes of chronic inflammation, including allergic inflammation. Metabolic changes in immune cells have a crucial role in their inflammatory or regulatory responses. This notion is reinforced by metabolic diseases influencing global energy metabolism, such as diabetes or obesity, which are known risk factors of severity in inflammatory conditions, due to the metabolic-associated inflammation present in these patients. Since several metabolic pathways are closely tied to T cell and macrophage differentiation, a better understanding of metabolic alterations in immune disorders could help to restore and modulate immune cell functions. This link between energy metabolism and inflammation can be studied employing animal, human or cellular models. Analytical approaches rank from classic immunological studies to integrated analysis of metabolomics, transcriptomics, and proteomics. This review summarizes the main metabolic pathways of the cells involved in the allergic reaction with a focus on T cells and macrophages and describes different models and platforms of analysis used to study the immune system and its relationship with metabolism.
Home-Based Exercise Training in Childhood-Onset Takayasu Arteritis: A Multicenter, Randomized, Controlled Trial
Authors: Astley Camilla , Clemente Gleice , Terreri Maria Teresa , Carneiro Camila G. , Lima Marcos S. , Buchpiguel Carlos Alberto , Leão Filho Hilton , de Sá Pinto Ana Lúcia , Silva Clovis Artur , Campos Lucia Maria Arruda , Aikawa Nadia Emi , Gil Saulo , Pereira Rosa Maria Rodrigues , Roschel Hamilton , Gualano Bruno 
Published: July 2021

IntroductionChildhood-onset Takayasu Arteritis (c-TA) is a rare, large-vessel vasculitis seen in children that could predisposing patients to a high risk of mortality. Exercise has the potential to improve overall health in several diseases, but evidence remains scant in c-TA. The main objective of this study was to investigate the safety and potential therapeutic effects of exercise in c-TA.MethodsThis was a 12-week, multicenter, randomized, controlled trial, to test the effects of a home-based, exercise intervention vs. standard of care in c-TA patients in remission. The primary outcomes were arterial inflammation, assessed by [18F] FDG- PET/MRI and systemic inflammatory markers. Secondary outcomes included, physical activity levels, functionality, body composition, disease-related parameters, and quality of life.ResultsThirty-seven patients were assessed for eligibility, which represents the total number of c-TA patients being followed by the three specialized medical ambulatory services in Sao Paulo. After exclusions, fourteen c-TA patients (71.4% females) aged 12-25 years were randomly allocated into exercised (n=5) and non-exercised groups (n=9). Exercise did not exacerbate arterial inflammation. In fact, exercised patients had a reduction in the frequency of vessel segments with severe inflammation, whereas the non-exercised patients had an opposite response (P=0.007). Greater improvements in visceral fat, steps per day, functionality and physical component SF-36 were observed in the exercised patients (P ≤ 0.05).ConclusionsExercise is safe and may improve visceral fat, physical activity levels, functionality, and physical component SF-36 in c-TA patients. Thus, exercise arises as a novel, evidence-based intervention to improve general health in c-TA.Clinical Trial Registrationhttps://www.clinicaltrials.gov/ct2/show/NCT03494062?term=NCT03494062&amp;draw=2&amp;rank=1, identifier NCT03494062.