bluuebunny/crossref_metadata_2025_split huggingface dataset:
Amphibole fractionation and its potential redox effect on arc crust: Evidence from the Kohistan arc cumulates
Authors: Zhang Jingbo , Wang Rui , Hong Jun 
Published: September 2021

Abstract
Arc magmas, a major contributor to continental crust growth, are thought to be more oxidized than mid-ocean ridge basalts as reflected by an enrichment in ferric iron relative to ferrous iron. But how arc magmas become oxidized is hotly debated. It is acknowledged that the fractionation of common Fe-rich phases (e.g., amphibole) may change the Fe valence of the derivative melt. Amphibole has Fe-rich compositions commonly found in arc systems. We present high-precision (±0.01%) Fe valence data of amphibole and cumulates from the Kohistan arc determined by Mössbauer spectroscopy and bulk cumulate Fe3+/ΣFe ratios by wet chemistry. We evaluate the Fe3+/ΣFe trend of Fe-rich amphibole during arc magma fractionation. Our results show that bulk Fe3+/ΣFe ratio of cumulates in mature island arc settings is mainly controlled by amphibole due to its abundance and decreases (from 0.4 to 0.2) with decreasing Mg# as Fe3+/ΣFe ratios decrease in amphibole (from 0.35 to 0.2). Our modeling suggests that amphibole fractionation from parental arc magmas to Fe3+/ΣFe above 0.2 may lead to an increase in Fe3+/ΣFe ratios of middle–late stage residual melts by 0.1–0.3, and the partitioning of ferrous Fe into amphibole increases with the evolution of arc magmas. Our findings highlight the importance of petrological processes in the magma that contribute to the production of fertile arc crust.
Sistem Jaminan Mutu dan Prediksi pada Rantai Pasok Ikan dari Perikanan Sungai
Authors: Ibrahim Muhammad Rivani , Mustafid Mustafid 
Published: September 2021

The supply chain system with quality assurance and fish prediction has important role for producers and consumers regarding the need for fresh fish to be consumed in certain size. The research aims to design quality assurance and predictive model for the fish supply chain system so that it is always available to consumers. The Fuzzy Tsukamoto method approach is used to design prediction model for required fish based on the fish provided by fishermen, and Fuzzy Mamdani approach is used to design model for quality assurance of fish needs that consumers need every week and month. This supply chain system is designed with upstream fishermen and fish sellers and as downstream fish retailers and fish consumers, while data analysis uses quantitative data sourced from fishermen and fish sellers and fish consumers. The prediction system and fish quality assurance provide output as a material for decision making in order to obtain information for agents and consumers that they can provide and supply fish as needed. A case study was conducted on the river fishery sector in Kota Bangun District.
Pioneering a Green Belt and Road Initiative (BRI) alignment between China and other members: mapping BRI's sustainability plan
Authors: Cheshmehzangi Ali , Xie Linjun , Tan-Mullins May 
Published: September 2021

AbstractThis study is the first attempt to explore the green development alignments between China and other BRI countries. It maps and presents the green agendas practiced in BRI countries by 2017 before exploring on the ground practices of China-led physical developments in these countries. 2017 is marked as the year China pledged to promote a greener BRI. This is achieved by examining how China's green BRI agenda and infrastructure development projects were undertaken in different partner countries. By doing so, we sought to identify gaps and opportunities for pursuing green developments across and through the BRI. The findings from this study contribute to the overall debate and exploration of sustainable development of BRI.
Applicability of different textile materials in filtration process integrated with SBR for wastewater reuse in small settlements
Authors: Gunes Sinem , Ayol Azize 
Published: September 2021

Abstract
In recent years, research activities on water reuse applications have rapidly increased to manage natural water sources efficiently. Although these applications in centralized treatment systems can be effective, there are some drawbacks, including the economic factors for small settlements. In this study, a textile filtration unit with the integration of a sequencing batch reactor (SBR) was developed and different textile materials were used to enhance the treated effluent quality for reuse purposes. While the textile filtration unit alone could not effectively remove the pollutants, the removal efficiencies could not exceed 36% for COD and 50% for BOD5. However, SBR integration in to the filtration system improved the treated wastewater quality and COD and BOD5 reductions were obtained higher than 93%. Activated carbon coated cotton textile materials and activated carbon cloth, which was used for the first time for wastewater treatment, increased the treatment performance. In the filtration system, although the suspended solids were high in the SBR effluent, no clogging problem was observed even with higher operation times. This paper presents the research results on this textile filtration system, and experimental findings are discussed on the applicability of the system for small communities.
Inflammation, Oxidative Stress, Vascular Aging and Atherosclerotic
Ischemic Stroke
Authors: Koutsaliaris Ioannis K. , Moschonas Iraklis C. , Pechlivani Louisa M. , Tsouka Aikaterini N. , Tselepis Alexandros D. 
Published: September 2021

Abstract:
Vascular aging is a crucial risk factor for atherosclerotic ischemic stroke. Vascular
aging is characterized by oxidative stress, endothelial dysfunction, inflammation, intimal
and media thickening, as well as the gradual development of arterial stiffness,
among other pathophysiological features. Regarding oxidative stress, increased concentration
of reactive oxygen and nitrogen species is linked to atherosclerotic ischemic stroke in
vascular aging. Additionally, oxidative stress is associated with an inflammatory response.
Inflammation is related to aging through the “inflammaging” theory, which is
characterized by decreased ability to cope with a variety of stressors, in combination with
an increased pro-inflammatory state. Vascular aging is correlated with changes in cerebral
arteries that are considered predictors of the risk for atherosclerotic ischemic stroke. The
aim of the present review is to present the role of oxidative stress and inflammation in
vascular aging, as well as their involvement in atherosclerotic ischemic stroke.
Accumulating Impact of Smoking and Co-morbidities on Severity and
Mortality of COVID-19 Infection: A Systematic Review and Meta-analysis
Authors: Kumar Rupesh , Rai Avdhesh Kumar , Phukan Mayur Mausoom , Hussain Anowar , Borah Debajit , Gogoi Bhaskarjyoti , Chakraborty Poulomi , Buragohain Alak Kumar 
Published: September 2021

Background:
High prevalence, severity, and formidable morbidity have marked the recent emergence of the novel coronavirus disease (COVID-19) pandemic. The significant association with the pre-existing co-morbid conditions has increased the disease burden of this global health emergency, pushing the patients, healthcare workers and facilities to the verge of complete disruption.

Methods:
Meta-analysis of pooled data was undertaken to assess the cumulative risk assessment of multiple co-morbid conditions associated with severe COVID-19. PubMed, Scopus, and Google Scholar were searched from January 1st to June 27th 2020 to generate a well-ordered, analytical, and critical review. The exercise began with keying in requisite keywords, followed by inclusion and exclusion criteria, data extraction, and quality evaluation. The final statistical meta-analysis of the risk factors of critical/severe and non-critical COVID-19 infection was carried out on Microsoft Excel (Ver. 2013), MedCalc (Ver.19.3), and RevMan software (Ver.5.3).

Results:
We investigated 19 eligible studies, comprising 12037 COVID-19 disease patients, representing the People’s Republic of China (PRC), USA, and Europe. 18.2% (n = 2200) of total patients had critical/severe COVID-19 disease. The pooled analysis showed a significant association of COVID-19 disease severity risk with cardiovascular disease (RR: 3.11, p < 0.001), followed by diabetes (RR: 2.06, p < 0.001), hypertension (RR: 1.54, p < 0.001), and smoking (RR: 1.52, p < 006).

Conclusion:
The review involved a sample size of 12037 COVID-19 patients across a wide geographical distribution. The reviewed reports have focused on the association of individual risk assessment of co-morbid conditions with the heightened risk of COVID-19 disease. The present meta-analysis of cumulative risk assessment of co-morbidity from cardiovascular disease, diabetes, hypertension, and smoking signals a novel interpretation of inherent risk factors exacerbating COVID-19 disease severity. Consequently, there exists a definite window of opportunity for increasing survival of COVID-19 patients (with high risk and co-morbid conditions) by timely identification and implementation of appropriately suitable treatment modalities.
A Systematic Review and Meta-analysis of Clinical Studies on Ankylosing Spondylitis and Neutrophil to Lymphocyte Ratio
Authors: Khorrampazhouh Nastaran , Omranzadeh Alireza , Fazeli Bahare , Zarifian Ahmadreza , Ghodsi Alireza , Amirkhanlou Fatemeh , Saberi Amin , Arekhi Soheil , Tork Mohammad Amin Bayat , Goudarzi Zeinab , Moghadam Maliheh Dadgar 
Published: September 2021

Background:Neutrophil to lymphocyte ratio (NLR) is a marker for many inflammatory diseases. Ankylosing spondylitis (AS) is among these inflammatory diseases, and many studies have compared the NLR ratio between patients with AS and healthy controls.Aim:This study aims to systematically review and analyze the available evidence about the significance of NLR values in AS.Method:Based on Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines, we searched Embase, Pubmed, ISI Web of Science, and Scopus databases from inception to August 2020 using (“Ankylosing spondyl* ” OR “Bechterew Disease” OR “Rheumatoid Spondylitis”) AND ((neutrophil* AND lymphocyte*) OR NLR) as key terms of the search strategy. Data selection and extraction were conducted separately by two authors. We appraised the included articles according to the Joanna Briggs checklist. Comprehensive Meta-analysis Version 2 was used for analysis and assessment of publication bias. I2 > 75% and p-value < 0.05 were considered significant.Result:In total, 182 studies resulted from a search in all databases. Duplicate removal, title, abstract, and full-text screening yielded 12 related studies, with 11 included in the meta-analysis. Quality assessment was satisfying in all studies. Pooled difference in NLR means value between patients and controls was 0.38 (95% CI: 0.24-0.52, p-value <0.0001). An I2 of 51% and a Cochran Q test p-value of <0.05 indicated moderate heterogeneity; thus, subgroup analysis had no indication. Publication bias was not significant (Funnel plot with an Egger’s intercept of -0.07; p-value=0.95).Conclusion:Significant higher amounts of NLR may be strongly indicative of underlying inflammation in AS.
Gait in Patients with Axial Spondyloarthritis: A Systematic Review of the
Literature
Authors: Soulard Julie , Vaillant Jacques , Vuillerme Nicolas 
Published: September 2021

:
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease predominantly affecting
the axial skeleton. axSpA includes radiographic (i.e., ankylosing spondylitis (AS)) and non-radiographic
forms (nr-axSpA). Although recent studies have reported that patients with AS have impaired
gait, axSpA’s consequences on gait remain unknown. The present review’s objectives were
to identify: 1) how gait is assessed in patients with axSpA, and 2) what the gait characteristics are
of patients with axSpA.
This systematic review’s protocol was registered in the Prospero database (CRD42020128509).
Three databases were systematically searched using keywords related to axSpA and gait. Two independent
reviewers selected the articles and extracted the data.
The search revealed two hundred titles and abstracts, and two articles were finally included in this
review, comprising a total of 132 patients with axSpA. One of the included studies used the 6 m
maximum gait velocity test (axSpA: 2.2 ± 0.5 m/s), and the other used the six-minute walk test
(axSpA: 414 ± 106 m). Neither study involved a control group to compare gait.
Only two published studies assessed the gait performance of patients with axSpA using clinical
tests. Furthermore, neither of them compared gait performance to healthy controls or differentiated
gait between the AS and nr-axSpA forms of axSPA. The present literature review highlights the
need for future research to learn more about how gait is impaired in different types of patients with
axSpA.
Rhododendron arboreum: A Critical Review on Phytochemicals, Health Benefits and Applications in the Food Processing Industries
Authors: Sharma Simple , Chaudhary Sahil , Harchanda Archu 
Published: September 2021

Abstract:Rhododendron is a resourceful, evergreen shrub or a small tree with an ornate display of scarlet red or pale pink flowers that belongs to the family Ericaceae. Rhododendron plants are traditionally used to treat numerous human ailments like blood dysentery, headache, asthma, cough, stomachache, fever, inflammation and fungal infections. Rhododendron also has economic, medicinal, and pharmacological importance. Rhododendron has been regarded as a rich source of secondary metabolites. Apart from aesthetic and sacred values, from past times, Rhododendron juice was prepared from the flowers to curb allergies, treat diabetes and deal with inflammations. Recent studies have shown several promising activities particularly relaxant, digestive enzyme, antioxidant, antimicrobial, antispasmodic, anticancer and antagonistic effects. With the rapidly growing popularity of Rhododendron arboreum, it is important to have a comprehensive reference for its nutritional benefits with the growing search for natural and healthy foods. This work aimed to review the recent advances in research carried out to date for the purposive evaluation of the nutritional quality and potential health benefits of Rhododendron arboreum for its utilization in food processing industries for composing novel value- added products, to achieve high consumer acceptability and health benefits.
Resuming Elective Ophthalmic Surgery during COVID-19 Pandemic
Authors: Shatnawi Raed , Al-latayfeh Motasem 
Published: September 2021

Background:
The Coronavirus (COVID-19) pandemic has become a global health problem.

Purpose:
This paper aims to describe the practical experience of resuming elective ophthalmic surgery during the COVID-19 pandemic in a specialized eye hospital.

Methods:
A descriptive design was conducted in Middle East Eye Hospital, Ammann, Jordan. The current practices were observed to be conducted according to many evidence-based measures, including mainly the American Academy of Ophthalmology guidelines to safely resume ophthalmology service during the COVID-19 pandemic.

Results:
The main strategies that were adopted were related to patient and employee awareness and education, infection control measures, medical instruments, clinical environment, administrative control, patient screening and workflow, and quality control.

Conclusion:
We expect that these strategies could help ophthalmologists globally to resume elective ophthalmic surgery.
Recruitment of Patients With Amyotrophic Lateral Sclerosis for Clinical Trials and Epidemiological Studies: Descriptive Study of the National ALS Registry’s Research Notification Mechanism
Authors: Mehta Paul , Raymond Jaime , Han Moon Kwon , Larson Theodore , Berry James D , Paganoni Sabrina , Mitsumoto Hiroshi , Bedlack Richard Stanley , Horton D Kevin 
Published: September 2021

Background
Researchers face challenges in patient recruitment, especially for rare, fatal diseases such as amyotrophic lateral sclerosis (ALS). These challenges include obtaining sufficient statistical power as well as meeting eligibility requirements such as age, sex, and study proximity. Similarly, persons with ALS (PALS) face difficulty finding and enrolling in research studies for which they are eligible.

Objective
The aim of this study was to describe how the federal Agency for Toxic Substances and Disease Registry’s (ATSDR) National ALS Registry is linking PALS to scientists who are conducting research, clinical trials, and epidemiological studies.

Methods
Through the Registry’s online research notification mechanism (RNM), PALS can elect to be notified about new research opportunities. This mechanism allows researchers to upload a standardized application outlining their study design and objectives, and proof of Institutional Review Board approval. If the application is approved, ATSDR queries the Registry for PALS meeting the study’s specific eligibility criteria, and then distributes the researcher’s study material and contact information to PALS via email. PALS then need to contact the researcher directly to take part in any research. Such an approach allows ATSDR to protect the confidentiality of Registry enrollees.

Results
From 2013 to 2019, a total of 46 institutions around the United States and abroad have leveraged this tool and over 600,000 emails have been sent, resulting in over 2000 patients conservatively recruited for clinical trials and epidemiological studies. Patients between the ages of 60 and 69 had the highest level of participation, whereas those between the ages of 18 and 39 and aged over 80 had the lowest. More males participated (4170/7030, 59.32%) than females (2860/7030, 40.68%).

Conclusions
The National ALS Registry’s RNM benefits PALS by connecting them to appropriate ALS research. Simultaneously, the system benefits researchers by expediting recruitment, increasing sample size, and efficiently identifying PALS meeting specific eligibility requirements. As more researchers learn about and use this mechanism, both PALS and researchers can hasten research and expand trial options for PALS.
Breakthrough and thermodynamic adsorption of Cr (VI) y Ni (II) bioadsorption in continuous system
Authors: Tejada Tovar Candelaria Nahir , Newball López Luis Carlos , Cardona Lara Camilo Esteban 
Published: September 2021

The removal of heavy metals present in water is an issue of environmental interest, due to bioaccumulation,
biomagnification and the carcinogenic and mutagenic effects on living beings. The objective of the present study was to use plantain peel residues in Chromium (VI) and Nickel (II) removal in continuous system, evaluating the effect of bedheight, temperature and adsorbent particle size on the process; obtaining a 98.7% 99.71% removal yield for Cr (VI) and Ni(II), respectively. The FTIR showed that the bioadsorbent has
a heterogeneous structure with the presence of hydroxyl groups, saturated and unsaturated hydrocarbons, carbonyls, carboxyl, among others, and it was established that the process is controlled by electrostatic reactions between the active centers and the metal. The breaka ge curve was carried out under the optimal conditions established by the Response Surface Methodology (RSM) and it was established that the
bioadsorbent has an extensive useful life, as it was not saturated throughout the process. The hermodynamic parameters established that the process is exothermic and irreversible, being favored at room temperature. Taking into account the behavior of plantain peels during the breakage curve, it is recommended to use it as a filler in a packed bed to remove Cr (VI) and Ni (II).
AKTIVITAS ANTIDIABETES EKSTRAK ETANOL DAUN BELIMBING BESI (Averhhoa carrambola) PADA MENCIT (Mus musculus)
Authors: WIDI YANTHI NI PUTU SRI PUSPITA , Astiti Ni Putu Adriani , Sudatri Ni Wayan 
Published: September 2021

Many antioxidant compounds, flavonoids, and saponins are contained in starfruit leaves (Averrhoa carambola). The purpose of this study was to determine the antidiabetic activity of star fruit extract in mice. This study used a completely randomized design (CRD) with 6 treatments, namely P1 (aquadest without alloxan) as a negative control, P2 (aquadest with alloxan) as a positive control, P3 (metformin 500 mg / kgBB), P4 (alloxan + ethanol extract of star fruit leaves. 100 mg / kgBB), P5 (alloxan + ethanol extract of star fruit leaves 150 mg / kgBB), P6 (alloxan + ethanol extract of star fruit leaves 200 mg / kgBB). The starfruit leaf extract was made using the maceration method. In order for experimental animals to become diabetic, alloxan is used at a dose of 120 mg / kgBW which is injected intramuscularly into the thigh muscles. After the experimental animals were diabetic, We were given ethanol extract of starfruit leaves according to the experimental design, starting from day 7th to day 21st. Blood glucose levels are measured with a glucometer every week. The results showed that the best decrease in blood glucose levels occurred in the first week and the second week. In the first week, the metformin treatment was able to reduce blood glucose by 88.4%, while the ethanol extract treatment of star fruit leaves at a dose of 200 mg / kg BW was able to reduce blood glucose levels by 60%. The ethanol extract of star fruit leaves has antidiabetic activity.
Keywords: mice, diabetes mellitus, blood glucose, starfruit leaves.
AKTIVITAS HARIAN DAN FREKUENSI BEGGING BEHAVIOUR DARI ELANG BONDOL (Haliastur indus) SITAAN DI PUSAT PENYELAMATAN SATWA, TABANAN, BALI
Authors: Widiyavedanta Gde Oka , Yuni Luh Putu Eswaryanti Kusuma , Ginantra I Ketut 
Published: September 2021

Brahminy kite (Haliastur indus) is one of bird of prey species that occupy position as top predator. Many brahminy kite was captured and was kept as pet which caused those birds lose their ability to hunt as a result of being caged for too long and for not to be trained to hunt. In Bali Wildlife Rescue Centre, the confiscated brahminy kite showed begging behavior in which the birds “whine” every time a human approach. This kind of behaviour affect their readiness to be released in the wild. The purpose of this study was to determine the daily activity and the frequency of begging behaviour of confiscated brahminy kite in Bali Wildlife Rescue Centre. This study was conducted in January 2020. This study found that the brahminy kite at the Bali Wildlife Rescue Centre spent the most of their time for perching. The second highest activity was preening, whereas the least activities were feeding and moving. The highest percentage to beg in brahminy kite was recorded in the morning, whereas the lowest percentage was in the midday. The results of this study indicate that the confiscated brahminy kite at the Bali Wildlife Rescue Centre still needs more time to be rehabilitated prior released ack into the wild.