bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Bispectral Index-Guided Total Intravenous Anesthesia on Post-Anesthetic Recovery Outcomes in High-Risk Children: A Prospective, Randomized, Controlled Trial
Authors: Liu Guoliang , Li Lijing , Zhang Xuemei , Wang Xiaoxue , Hua Lei , Zheng Chao , Gao Jia , Hao Wei , Zhang Jianmin , Wang Fang 
Published: November 2021

Abstract
BACKGROUND TIVA is widely used in children, but few studies have attempted to evaluation of the effect of BIS-guided propofol infusion than that on conventional methods on recovery outcomes in children with higher risk factors.OBJECTIVETo evaluate the effect of bispectral index (BIS) guidance during total intravenous anesthesia on post-anesthetic recovery outcomes in children at higher risk during anesthesia. DESIGNA prospective, randomized, controlled trial. SETTING University medical centre.PATIENTSThis study enrolled 472 children (aged 1-14 years) who met the higher-risk scoring criteria and were scheduled for surgery under total intravenous anesthesia. INTERVENTIONThe children were randomly assigned to the BIS group (group B) and standard clinical practice group (group S). The BIS values in group B were maintained at 45–60. The anesthesiologist controlled the depth of anesthesia in group S according to the variation in the clinical signs of the children. MAIN OUTCOME MEASURESBIS values, heart rate (HR), mean arterial pressure (MAP), and pulse oxygen saturation at each time points, as well as the time between drug withdrawal to extubation, duration of stay in the post-anesthesia care unit (PACU), the total amount of propofol used, and postoperative adverse reactions were recorded. RESULTSThere was no significant difference in time from stopping propofol infusion to extubation and duration of PACU between the groups . There was no significant difference in BIS values between the groups at T2, T3, and T8. BIS values at T1, T4, T5, T6, and T7 in group B were lower than those in group S. There was no statistically significant difference in the HR between the groups. MAP in group B was lower than in group S at T5, T6, T7, and T8. The total amount of propofol administered in group B was higher than in group S. CONCLUSIONThe use of BIS-guided total intravenous anesthesia in higher-risk children can maintain the proper depth of anesthesia but does not prolong the time of extubation and the duration of stay in the PACU.TRIAL REGISTRATION Chictr.org.cn identifier: 24/11/2017 , ChiCTR-IOR-17013530
The Role of Community Health Advisors’ Cancer History in Implementation and Efficacy of a Cancer Control Intervention
Authors: Huq Maisha R. , He Xin , Woodard Nathaniel , Chen Chang , Knott Cheryl L 
Published: November 2021

Abstract
Purpose: Community health advisors (CHAs) play a key role in promoting health in medically underserved communities, including in addressing cancer disparities. There is a need to expand the research on what criteria makes for an effective CHA. We examined the relationship between CHAs’ personal and family history of cancer, and implementation and efficacy outcomes in a cancer control intervention trial.Methods: Twenty-eight trained CHAs implemented a series of three cancer educational group workshops for N=375 workshop participants across 14 churches. Implementation was operationalized as participant attendance at the educational workshops and efficacy as workshop participants’ cancer knowledge scores at 12-month follow-up, controlling for baseline scores. Results: CHA’s personal history of cancer was not significantly associated with implementation, nor knowledge outcomes. However, CHAs with family history of cancer had significantly greater participant attendance at the workshops than CHAs without family history of cancer (p=.03). In addition, there was a significant, positive association between male CHAs’ family history of cancer and male workshop participants’ prostate cancer knowledge scores at 12 months (estimated beta coefficient=0.49, p<.01) after adjusting for workshop participant baseline knowledge scores, the CHAs’ competence score, and the CHAs’ education levels. Conclusions: Findings suggest CHAs with family history of cancer may be particularly suitable for cancer peer education, though further research is needed to confirm this and identify other factors conducive to CHAs’ success.
Differences in The Causes of Light And Extreme Precipitation For The Qaidam Basin In Summer
Authors: Li Yan , Lv Chunyan , Chen Jun , Feng Juan , Yang Qingyi 
Published: November 2021

Abstract
The Qaidam Basin (QB) locates over the northeast of the Tibetan Plateau (TP), where precipitation especially extreme precipitation possesses obvious local characteristics compared with that over the whole TP. This study tries to investigate cause of light (50% threshold) and extreme (95% threshold) precipitation in boreal summer in the QB, which is helpful to deepen understanding of the mechanism of precipitation formation in different regions of the TP. The extreme (light) precipitation thresholds in the eastern QB are greater than that in the western QB, with a value of 6~16mm (2mm) for most regions. There are two main moisture transport channels for light and extreme precipitation events. One is from the Eurasia and carried by the westerlies, which provides 48.2% and 55.8% of moisture for light and extreme precipitation events, respectively. The other moisture transport channel is from the Arabian Sea and the Bay of Bengal, which is transported toward the QB at the joint role of the South Asian summer monsoon and the plateau monsoon, contributing 51.8% and 44.2% of moisture for light and extreme precipitation events, respectively. The stronger moisture transport to precipitation mostly attributes to the enhanced moisture influxes from the western and southern boundaries. Additionally, the weaker moisture outflux across the eastern boundary is also responsible for the extreme precipitation. The circulation characteristics shows that, the precipitation in the QB has a closely relationship with the weak ridge over the Caspian Sea and Aral Sea, the enhanced South Asian summer monsoon and plateau monsoon, which are conducive to the moisture transport from the Eurasia and low-latitudes toward the QB. The meridional circulation enhances, meantime the westerly jet stream splits into east- and west-branch, and the south Asian high (SAH) strengthens, which are beneficial for the stronger convective motion. Especially, the trough in the northwest of the QB and the more significant east- and west-branch structure of westerly jet are the main circulation characteristics for the extreme precipitation events. Further analysis reveals that the apparent heat source over the QB is contributed to more synchronous moisture transport around the TP and its surrounding areas for light precipitation events, while the apparent heat source enhances 1 day prior to moisture transport from the east part region of the South Asian summer monsoon to around the eastern TP for extreme precipitation events. Meantime, the apparent heat source triggers an abnormal cyclone over the TP which can positively strength the local convective motion. Such abnormal configuration of atmospheric circulation and the influence of apparent heat source can explain the difference in cause of precipitation with different magnitude to a great extent in the QB.
Point-of-Care Biomedical Engineering Equipment Management System
Authors: Wu Hsin-Chen , Yang Jia-Xian , Hsu Wan-Lun , Chen Duan-Yu , Liao Li-Jen 
Published: November 2021

Abstract
BackgroundMedical devices and equipment play an important role in the modern medical service. It is necessary to integrate the relevant information in order to effectively manage all the equipment into a biomedical engineering equipment management system (BEEMS). Aims: To report our experience and satisfactory from the users of a BEEMS.MethodWe combine a central core module with intra-net and a mobile device application with internet to become a real-time BEEMS. With the combination of these two modules, the point-of-care software system become real-time and mobile for all users in the hospital. We conduct a survey about satisfactory from the users after more than one-year implementation of this system. ResultsAfter the application more than one year, only 7% users show unsatisfactory about the BEEMS. We also find this real-time and point-of-care BEEMS has high satisfactory and is especial helpful for the management staff in hospital. ConclusionA real-time BEEMS has high satisfactory and is helpful for the staff in hospital.Relevance to clinical practiceA real-time biomedical engineering equipment management system is helpful to effectively manage all the equipment in hospital.
Self-Assembly of Silver Clusters into One- and Two-Dimensional Structures as Artificial Intelligent Sensors of Alcohol
Authors: Li Gao , Qin Zhaoxian , Sharma Sachil , Peng Yongwu 
Published: November 2021

Abstract
Reggeization and response to external stimulus is an important part of artificial intelligence, which would significantly improve the quality of life in the future. The development of new materials for the design of sensitive and responsive sensors has become a crucial component. Here, two silver cluster-based polymers (Ag-CBPs), including one-dimensional (1D) {Ag22(L1)8(CF3CO2)14(CH3OH)2}n chain and two-dimensional (2D) {[Ag12(L2)2(CO2CF3)14(H2O)4(AgCO2CF3)4](HNEt3)2}n film, are designed and used to simulate the human nose - an elegant sensor to smells, to distinguish organic solvents. We study the relationship between the atomic structures of Ag-CBPs determined by X-ray diffraction and electrical properties in the presence of organic solvents (e.g. methanol, ethanol). The ligands, cations and the ligated solvent molecules not only play an important role in the self-assembly process of Ag-CBP materials, but also determine their physiochemical properties. An application of cluster-based polymers is demonstrated in the artificial intelligent sensors.
Agglomerate Fog Early Warning Method based on GWR Model
Authors: Wang Qi , Hai-xia FENG , NING Er-wei , LI Jian , Yao-kun CHAI , Shou-dong JIA 
Published: November 2021

Abstract
In order to realize the early warning of Agglomerate fog-prone sections, reduce accidents and ensure the safety of personal and property. Taking Shandong Province as an example, according to the statistics of the time and location of the roads where the agglomerate fog occurs and the number of occurrences in 2018, the time and space analysis of the agglomerate fog occurrence is carried out, and combined with the analysis of the correlation between the frequent occurrence of agglomerate fog and the elevation of Shandong Province, river density, and Normalized Difference Vegetation Index (NDVI), construction of Geographically Weighted Regression (GWR) model to study the geographical environment conditions of highways prone to foggy weather, the influence of regional altitude, river density analysis and NDVI on the occurrence of agglomerated fog. The research results show that the number of agglomerate fog occurrences in different regions has a strong spatial correlation, that is, the environment of different regions has a greater impact on the number of agglomerate fog occurrences. The agglomerate fog early warning model built with regional river density, elevation difference and NDVI as independent variables can effectively predict agglomerate fog-prone areas. The prediction result shows that more than 98% of the area is within the allowable range of error.
Enhanced Expression of Serum miR-410-3p Reflects The Disease Progression in Anti-gp210 Positive Primary Biliary Cholangitis
Authors: Xu Tiantian , Wang Pan , Wang Zhan , Wang Lin , Li Wenshuai , Sun Guirong , Liu Mingjun 
Published: November 2021

Abstract
Background & Aims: Anti-gp210 antibodies are highly specific for primary biliary cholangitis (PBC) and are detected in 20%-40% of PBC patients. PBC patients with anti-gp210 positive appear to have more advanced bile duct damage and worst prognosis. Recent studies suggest that miRNAs play a critical role in the progression of PBC. The aim of this study was to explore the relationship between the expression dysregulation of miRNAs in serum from patients with anti-gp210 positive PBC and the disease progression.Methods: The differentially expressed miRNAs were identified by deep sequencing. The differentially expressed miRNAs were validated by qRT-PCR in PBC patients along with healthy controls and chronic hepatitis B patients. The target genes of differentially expressed miRNAs were predicted using TargetScan and miRDB database. Gene ontology and KEGG pathway analyses were conducted to explore the target genes function. Results: The expression levels of 60 miRNAs were found to differ significantly between PBC patients with anti-gp210 positive and anti-gp210 negative. MiR-410-3p was validated as the significantly differentially expressed miRNA. MiR-410-3p had a higher level in patients with anti-gp210 positive PBC and was associated with the disease progression. Bioinformatics showed that underlying target genes of miR-410-3p was involved in cell communication, signal transduction, cell apoptosis, and so on. Through KEGG pathway analysis, we suspected that Th1, Th2, Th17 cell differentiation might be associated with the pathogenesis of PBC. Conclusion: The over-expression of serum miR-410-3p might reflect the disease progression in patients with anti-gp210 positive PBC.
Inter-Incisive Index in South Bulgarians and Its Application in Aesthetic Dentistry
Authors: Harizanova Zdravka , Baltadjiev Atanas , Popova Ferihan , Peycheva Marieta , Boyaci Emre 
Published: November 2021

Abstract
Background: In recent years, aesthetic dentistry has become a major focus for the public. Facial attractiveness plays a key role on modern society and the creation of harmonious smile is an aim for every dentist.The aim of this study was to define certain values of the inter-incisive index in South Bulgarians, the sexual dimorphism and bilateral asymmetry and to verify differences of this index between Bulgarians and other Balkan populations.Materials and methods: The present study included 86 males and 83 females of Bulgarian origin living in South Bulgaria aged 20-40 years. Mesiodistal dimensions of maxillary central and lateral incisors were measured by Dentistry Sliding Vernier Caliper. We used the technique of Martin-Saller, modified by Prof. Y. Yordanov. We calculated the inter-incisive index as ratio of the mesiodistal dimension of maxillary lateral incisor to the mesiodistal dimension of the maxillary central incisor. The measurements were analyzed with SPSS 23. The level of statistical significance was set at P< 0.05. Results: The inter-incisive index showed no statistically significant differences between left and right side of the dental arch in both sexes. We did not find statistically significant differences between males and females as well. On the other hand we found statistically significant differences in MD values of incisors between Bulgarians and other Balkan nations.Conclusion: Inter-incisive index shows no sexual dimorphism and bilateral asymmetry in South Bulgarians. This can be helpful in aesthetic dentistry, in prosthodontics and in orthodontic treatment planning.
Molecular and morphological characterization of a first report of Cactodera torreyanae Cid del Prado Vera & Subbotin, 2014 (Nematoda: Heteroderidae) from Minnesota, the United States of America
Authors: Handoo Zafar A. , Skantar Andrea M. , Subbotin Sergei A. , Kantor Mihail R. , Hult Maria N. , Grabowski Michelle 
Published: November 2021

Abstract

Cactodera torreyanae Cid del Prado Vera & Subbotin, 2014 cysts were discovered during a Pale Potato Cyst Nematode (PCN) survey conducted by Minnesota Department of Agriculture as part of the Animal and Plant Health Inspection Service (APHIS) efforts to survey states for the presence of PCN. The soil samples were collected from a potato field, located in Karlstad, Kittson County, Minnesota, USA. Two out of 175 vials submitted for identification to the Mycology and Nematology Genetic Diversity and Biology Laboratory (MNGDBL) contained few cysts and juveniles of C. torreyanae. Cysts were dark brown in color, lemon-shaped to elongated with distinct vulval cone. Vulva with denticles present around fenestra, cyst length to width ratio between 1.6 and 2.3 and anus distinct. The juveniles had rounded stylet knobs, some sloping slightly posteriorly. The molecular analysis included sequence and phylogenetic analysis of ITS rRNA, D2-D3 expansion segments of 28S rRNA and COI of mtDNA genes. The nematode species was identified by both morphological and molecular means as Cactodera torreyanae. To the best of our knowledge this represents the first report of Cactodera torreyanae from the United States and first report of this cyst nematode species from potato fields. Definite host plant for this nematode remains unknown.
Features of seasonal growth of Arundo donax var. versicolor Mill. (Stokes) in the conditions of the M. M. Gryshko National Botanical Garden of the National Academy of Sciences of Ukraine
Authors: Shcherbakova T. O. 
Published: November 2021

Purpose. To define of phenological and morphological features of A. donax var. versicolor growth during the introduction in the M. M. Gryshko National Botanical Garden of the National Academy of Sciences of Ukraine (NBG).
Methods. The object of research was the plants of A. donax var. versicolor in the collection of ornamental grasses of the department of flower and ornamental plants of NBG. The plants were grown on a sunny experimental area during 2014–2020. Since under NBG conditions, A. donax var. versicolor did not enter the flowering phase, the beginning of the phases of spring regrowth, leaf unfolding, and the end of the growing season were recorded. Morphometric parameters and shoot-forming ability were investigated for 3–5 years of cultivation.
Results. The beginning and duration of the phases of shoot spring regrowth and the unfolding of leaves of A. donax var. versicolor as well as their dependence on the sum of effective temperatures was established. Thus, spring regrowth begins with renewal buds on May 11 ± 5 days at the effective temperature sums of 226.6 ± 19.7 °С. The phase of leaf development in plants occurred on May 20 ± 7 days. The effective temperature sum at the beginning of this phase was 309.45 ± 11.66 °C. The productivity of shoot formation (1.6 ± 0.3 shoot per plant) under the conditions of introduction was determined.
Conclusions. A. donax var. versicolor plants did not have a full cycle of seasonal development in the conditions of the NBG. Plants formed vegetative monocyclic shoots 240–260 cm tall. The duration of their vegetation was 182–189 days. The optimal period for the growth of the ground mass of plants fell on July-August. During this period, the leaves were quickly formed, the number of which was 28.8 ± 6.68 on the shoot. The correlation between the rate of accumulation of effective temperatures and the rate of regrowth of plant shoots was recorded.
Design and performance analysis of a renewable pumping system for treated wastewater to reuse in the Moroccan desert
Authors: Achag Badre , Mouhanni Hind , Bendou Abdelaziz 
Published: November 2021

Abstract
Treated wastewaters are an important alternative water supply for communities in dry climates all over the world. This study investigates using waste stabilization ponds (WSPs) to treat wastewater and the design of a solar photovoltaic pumping system to transfer the water to an Oasis in the Moroccan desert. The Oasis is currently about 5 ha in size and is irrigated with 24 m3/day of underground water. The wastewater is subjected to physicochemical and bacteriological analyses, also monitoring of operation, maintenance and loading rates of the WSPs for 12 months. To build a solar water pumping system, data on the system's components as well as local climatic data are obtained. The design optimization is done by simulation software PVsyst. WSPs provide reduced rates of BOD and fecal coliforms of 95 and 99%, respectively, with an average effluent concentration of 20 mg/l and 195 CFU. The exploitation of solar energy for pumping 24 m3/day requires five panels with a unit nominal power of 440 W for each panel and 2200 W for the entire system. This allows us to save about 1,500 kg of CO2 emissions per year, protect the region's fragile water resources and ensure the sustainability of the Oasis.
USO DE TECNOLOGIAS DE INFORMAÇÃO E COMUNICAÇÃO COMO ESTRATÉGIA EDUCATIVA SOBRE ALEITAMENTO MATERNO: RELATO DE EXPERIÊNCIA
Authors: Diniz da Silva Hémyllen Taísa , Pereira de Lima Jessyellen , De Araújo Pereira Leonara Carla , Martins Azevedo Castro Gabrielle Mahara 
Published: November 2021

Introdução: O aleitamento materno é uma prática recomendada de forma exclusiva até os 6 meses de idade e complementado por 2 anos ou mais, diante dos vários benefícios cientificamente comprovados tanto para a mãe quanto para o bebê. O leite materno protege a criança contra infecções, previne contra asma, diabetes e obesidade e está associado ao melhor crescimento e desenvolvimento. Objetivo: Relatar a experiência da produção de materiais educativos sobre benefícios e manejo da amamentação por meio de tecnologias de informação e comunicação, utilizados em um curso de educação à distância para profissionais, promovido por um Hospital Universitário do Rio Grande do Norte. Metodologia: Trata-se de um relato de experiência de uma ação educativa e de promoção à saúde. Estes materiais foram incluídos como parte do conteúdo do curso de manejo clínico em aleitamento materno para 2020, no formato de ensino à distância (EAD) em virtude da pandemia provocada pelo Covid-19. Foram realizadas duas produções de áudio em formato de Podcasts e um deles integrado a uma produção em vídeoaula para continuação do tema educativo abordado. Resultados: Elencado os principais benefícios do aleitamento materno exclusivo de forma lúdica. O primeiro Podcast retrata uma situação fictícia onde um recém-nascido é amamentado exclusivamente e evolui com baixo ganho de peso. Uma videoaula foi elaborada para explicar de forma dinâmica a condução do caso fictício no Podcast. O segundo Podcast tratou sobre os benefícios do aleitamento materno a longo prazo, pela simulação de uma entrevista de rádio entre locutor e nutricionista. Conclusões: Os materiais produzidos, por meio de ferramentas tecnológicas acessíveis, tornam o processo de aprendizado à distância mais ativo e dinâmico dentro de um contexto de afastamento social.
Non-coding RNAs in Necrotizing Enterocolitis- A New Frontier?
Authors: Nair Jayasree , Maheshwari Akhil 
Published: November 2021

Abstract:
With the recognition that only 2% of the human genome encodes for a protein, a large
part of the “non-coding” portion is now being evaluated for a regulatory role in cellular processes.
These non-coding RNAs (ncRNAs) are subdivided based on the size of the nucleotide transcript into
microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), but most of our attention has
been focused on the role of microRNAs (miRNAs) in human health and disease. Necrotizing enterocolitis
(NEC), an inflammatory bowel necrosis affecting preterm infants, has a multifactorial, unclear
etiopathogenesis, and we have no specific biomarkers for diagnosis or the impact of directed
therapies. The information on ncRNAs, in general, and particularly in NEC, is limited. Increasing
information from other inflammatory bowel disorders suggests that these transcripts may play an
important role in intestinal inflammation. Here, we review ncRNAs for definitions, classifications,
and possible roles in prematurity and NEC using some preliminary information from our studies
and from an extensive literature search in multiple databases including PubMed, EMBASE, and
Science Direct. miRNAs will be described in another manuscript in this series, hence in this
manuscript we mainly focus on lncRNAs.