bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of earth system model and atmospheric inversion using total column CO2 observations from GOSAT and OCO-2
Authors: Patra Prabir K. , Hajima Tomohiro , Saito Ryu , Chandra Naveen , Yoshida Yukio , Ichii Kazuhito , Kawamiya Michio , Kondo Masayuki , Ito Akihiko , Crisp David 
Published: April 2021

AbstractThe measurements of one of the major greenhouse gases, carbon dioxide (CO2), are being made using dedicated satellite remote sensing since the launch of the greenhouse gases observing satellite (GOSAT) by a three-way partnership between the Japan Aerospace Exploration Agency (JAXA), the Ministry of Environment (MoE) and the National Institute for Environmental Studies (NIES), and the National Aeronautics and Space Administration (NASA) Orbiting Carbon Observatory-2 (OCO-2). In the past 10 years, estimation of CO2 fluxes from land and ocean using the earth system models (ESMs) and inverse modelling of in situ atmospheric CO2 data have also made significant progress. We attempt, for the first time, to evaluate the CO2 fluxes simulated by an earth system model (MIROC-ES2L) and the fluxes estimated by an inverse model (MIROC4-Inv) using in situ data by comparing with GOSAT and OCO-2 observations. Both MIROC-ES2L and MIROC4-Inv fluxes are used in the MIROC4-atmospheric chemistry transport model (referred to as ACTM_ES2LF and ACTM_InvF, respectively) for calculating total column CO2 mole fraction (XCO2) that are sampled at the time and location of the satellite measurements. Both the ACTM simulations agreed well with the GOSAT and OCO-2 satellite observations, within 2 ppm for the spatial maps and time evolutions of the zonal mean distributions. Our results suggest that the inverse model using in situ data is more consistent with the OCO-2 retrievals, compared with those of the GOSAT XCO2 data due to the higher accuracy of the former. This suggests that the MIROC4-Inv fluxes are of sufficient quality to evaluate MIROC-ES2L simulated fluxes. The ACTM_ES2LF simulation shows a slightly weaker seasonal cycle for the meridional profiles of CO2 fluxes, compared with that from the ACTM_InvF. This difference is revealed by greater XCO2 differences for ACTM_ES2LF vs GOSAT, compared with those of ACTM_InvF vs GOSAT. Using remote sensing–based global products of leaf area index (LAI) and gross primary productivity (GPP) over land, we show a weaker sensitivity of MIROC-ES2L biospheric activities to the weather and climate in the tropical regions. Our results clearly suggest the usefulness of XCO2 measurements by satellite remote sensing for evaluation of large-scale ESMs, which so far remained untested by the sparse in situ data.
Analysis of cognitive skill in a water discharge activity for firefighting robots
Authors: Tamura Yoshihiro , Amano Hisanori , Ota Jun 
Published: April 2021

AbstractTeleoperated robots are expected to perform tasks in unexpected disaster sites, which have become increasingly common in recent years. However, only few teleoperated robots are used for such purposes owing to their poor usability compared to the handling of such tasks by humans. Further, human-machine interfaces (HMI) used in teleoperated robots are closely related to human skills. Firefighting activities require cognitive skill to make appropriate decisions. In extinguishing a fire or attenuating a leaked combustible gas, firefighting activities consist of two tasks: reconnaissance and water discharge to stop the fire or attenuate the leaked combustible gas, and these tasks possess different properties. In this study, we compared the cognitive skill of ten firefighters (five novices and five experts) in attenuating the leaked combustible gas, the latter of the said two tasks, using a teleoperated robot at a fire department. The experimental results indicated that experts were more multifaceted in their evaluation of the attenuation of combustible gas as compared to novices. In addition, as this result related to firefighter decision-making mechanisms, we were motivated to improve the HMI of firefighting teleoperated robots.
Preparation of the polyester/cotton composite yarn with alternating segmented structure and interval color via a promising physical spinning approach
Authors: Wei Wei , Tang Qinglun , Tang Hengxing , Chen Jun , Yan Kun , Wang Dong 
Published: April 2021

AbstractHerein, a novel kind of composite yarn with alternating segmented structure and interval color has been prepared based on a ring spinning approach. By adjusting the relative motion and blend ratio of the colored polyester filament and natural cotton staple fiber in yarn spinning process, a series of composite yarns were designed and prepared with various segmented structure and cyclical change of the distinct colors. The blend ratio was found to strongly influence on the segment frequency and yarn performance, achieving an improved mechanical property and yarn performance. A color systematic analysis indicated that the combination of alternating structural change induced interval color sense and gradient at the merged regions would lead to an enhanced stereoscopic visual effect of the composite yarns. Moreover, the composite yarns were confirmed to have an excellent weavability and able to endow different patterns and visual effects to the textiles. Thus, considering of the above advantages and multifunctionalities, this work should spur great possibilities for dyeing industry with the promising physical spinning method.
Cooperation & Liaison between Universities & Editors (CLUE): recommendations on best practice
Authors:   on behalf of the CLUE Working Group, Wager Elizabeth , Kleinert Sabine 
Published: April 2021

Abstract
Background
Inaccurate, false or incomplete research publications may mislead readers including researchers and decision-makers. It is therefore important that such problems are identified and rectified promptly. This usually involves collaboration between the research institutions and academic journals involved, but these interactions can be problematic.

Methods
These recommendations were developed following discussions at World Conferences on Research Integrity in 2013 and 2017, and at a specially convened 3-day workshop in 2016 involving participants from 7 countries with expertise in publication ethics and research integrity. The recommendations aim to address issues surrounding cooperation and liaison between institutions (e.g. universities) and journals about possible and actual problems with the integrity of reported research arising before and after publication.

Results
The main recommendations are that research institutions should:

develop mechanisms for assessing the integrity of reported research (if concerns are raised) that are distinct from processes to determine whether individual researchers have committed misconduct;

release relevant sections of reports of research integrity or misconduct investigations to all journals that have published research that was investigated;

take responsibility for research performed under their auspices regardless of whether the researcher still works at that institution or how long ago the work was done;

work with funders to ensure essential research data is retained for at least 10 years.

Journals should:

respond to institutions about research integrity cases in a timely manner;

have criteria for determining whether, and what type of, information and evidence relating to the integrity of research reports should be passed on to institutions;

pass on research integrity concerns to institutions, regardless of whether they intend to accept the work for publication;

retain peer review records for at least 10 years to enable the investigation of peer review manipulation or other inappropriate behaviour by authors or reviewers.

Conclusions
Various difficulties can prevent effective cooperation between academic journals and research institutions about research integrity concerns and hinder the correction of the research record if problems are discovered. While the issues and their solutions may vary across different settings, we encourage research institutions, journals and funders to consider how they might improve future collaboration and cooperation on research integrity cases.
Why are the batteries in the microwave?: Use of semantic information under uncertainty in a search task
Authors: Rehrig Gwendolyn L. , Cheng Michelle , McMahan Brian C. , Shome Rahul 
Published: April 2021

AbstractA major problem in human cognition is to understand how newly acquired information and long-standing beliefs about the environment combine to make decisions and plan behaviors. Over-dependence on long-standing beliefs may be a significant source of suboptimal decision-making in unusual circumstances. While the contribution of long-standing beliefs about the environment to search in real-world scenes is well-studied, less is known about how new evidence informs search decisions, and it is unclear whether the two sources of information are used together optimally to guide search. The present study expanded on the literature on semantic guidance in visual search by modeling a Bayesian ideal observer’s use of long-standing semantic beliefs and recent experience in an active search task. The ability to adjust expectations to the task environment was simulated using the Bayesian ideal observer, and subjects’ performance was compared to ideal observers that depended on prior knowledge and recent experience to varying degrees. Target locations were either congruent with scene semantics, incongruent with what would be expected from scene semantics, or random. Half of the subjects were able to learn to search for the target in incongruent locations over repeated experimental sessions when it was optimal to do so. These results suggest that searchers can learn to prioritize recent experience over knowledge of scenes in a near-optimal fashion when it is beneficial to do so, as long as the evidence from recent experience was learnable.
Improved X-ray baggage screening sensitivity with ‘targetless’ search training
Authors: Muhl-Richardson Alex , Parker Maximilian G. , Recio Sergio A. , Tortosa-Molina Maria , Daffron Jennifer L. , Davis Greg J. 
Published: April 2021

AbstractWhen searching for a known target, mental representations of target features, or templates, guide attention towards matching objects and facilitate recognition. When only distractor features are known, distractor templates allow irrelevant objects to be recognised and attention to be shifted away. This is particularly true in X-ray baggage search, a challenging real-world visual search task with implications for public safety, where targets may be unknown, difficult to predict and concealed by an adversary, but distractors are typically benign and easier to identify. In the present study, we draw on basic principles of distractor suppression and rejection to investigate a counterintuitive ‘targetless’ approach to training baggage search. In a simulated X-ray baggage search task, we observed significant benefits to target detection sensitivity (d′) for targetless relative to target-based training, but no effects of performance-contingent rewards or the inclusion of superordinate semantic categories during training. The benefits of targetless search training were most apparent for stimuli involving less spatial overlap (occlusion), which likely represents the difficulty and greater individual variation involved in searching more visually complex images. Together, these results demonstrate the effectiveness of a counterintuitive targetless approach to training target detection in X-ray baggage search, based on basic principles of distractor suppression and rejection, with potential for use as a real-world training tool.
Finite element analysis of reinforced concrete deep beam with large opening
Authors: Ismail Elsayed , Issa Mohamed S. , Elbadry Khaled 
Published: April 2021

Abstract
Background
A series of nonlinear finite element (FE) analyses was performed to evaluate the different design approaches available in the literature for design of reinforced concrete deep beam with large opening. Three finite element models were developed and analyzed using the computer software ATENA. The three FE models of the deep beams were made for details based on three different design approaches: (Kong, F.K. and Sharp, G.R., Magazine of Concrete Res_30:89-95, 1978), (Mansur, M. A., Design of reinforced concrete beams with web openings, 2006), and Strut and Tie method (STM) as per ACI 318-14 (ACI318 Committee, Building Code Requirements for Structural Concrete (ACI318-14), 2014). Results from the FE analyses were compared with the three approaches to evaluate the effect of different reinforcement details on the structural behavior of transfer deep beam with large opening.

Results
The service load deflection is the same for the three models. The stiffnesses of the designs of (Mansur, M. A., Design of reinforced concrete beams with web openings, 2006) and STM reduce at a load higher than the ultimate design load while the (Kong, F.K. and Sharp, G.R., Magazine of Concrete Res_30:89-95, 1978) reduces stiffness at a load close to the ultimate design load. The deep beam designed according to (Mansur, M. A., Design of reinforced concrete beams with web openings, 2006) model starts cracking at load higher than the beam designed according to (Kong, F.K. and Sharp, G.R., Magazine of Concrete Res_30:89-95, 1978) method. The deep beam detailed according to (Kong, F.K. and Sharp, G.R., Magazine of Concrete Res_30:89-95, 1978) and (Mansur, M. A., Design of reinforced concrete beams with web openings, 2006) failed due to extensive shear cracks. The specimen detailed according to STM restores its capacity after initial failure. The three models satisfy the deflection limit.

Conclusion
It is found that the three design approaches give sufficient ultimate load capacity. The amount of reinforcement given by both (Mansur, M. A., Design of reinforced concrete beams with web openings, 2006) and (Kong, F.K. and Sharp, G.R., Magazine of Concrete Res_30:89-95, 1978) is the same. The reinforcement used by the STM method is higher than the other two methods. Additional reinforcement is needed to limit the crack widths. (Mansur, M. A., Design of reinforced concrete beams with web openings, (2006)) method gives lesser steel reinforcement requirement and higher failure load compared to the other two methods.
Evaluation of physicochemical stability and degradation kinetics of bedaquiline in hydrolytic solutions of different pH
Authors: Rajput S. J. , Vanavi P. J. 
Published: April 2021

Abstract
Background
Tuberculosis is an infection that has high mortality rate in human as well as in animals if it remains unattained for long time. Scientists are always desirous to discover new molecules against Mycobacterium tuberculosis; one of them is bedaquiline which was recently approved to treat multidrug resistance TB. During the clinical study of new molecule stability and impurity are the key aspects to develop formulation. Stability issues in bulk drug are dangerous to drug safety and needs careful attention in formulation development. Bedaquiline stability study was completed with reversed-phase high-performance liquid chromatography (HPLC) and utilized in degradation kinetic study of bedaquiline in aqueous condition under different pH, temperature, and concentrations of degradant.

Results
Linearity was obtained in 50.0-250.0μg/ml, correlation coefficient, and regression line equation were 0.998 and Y=18528x + 7E+06 respectively. Intraday, inter day precision, and repeatability RSD were less than 2.0%. Average recovery in accuracy study was more than 98.0% showed that good recovery was obtained. Degradation kinetics parameters like activation energy (Ea), half-life (t50), rate constant (k), and shelf life (t90) were calculated under different condition for bedaquiline. Entropy and enthalpy of reaction was studied to gather knowledge about energy of system.

Conclusion
The result explained that bedaquiline degradation was pH-dependant, as increase in concentration of degradant and temperature, there was increase in degradation rate of bedaquiline. Bedaquiline was stable in neutral aqueous condition and at lower temperatures, shows that drug is hydrophobic in nature. Kinetic data showed that bedaquiline followed first order kinetics in acidic and alkaline pH.
Electronic Geriatric Assessment: Is It Feasible in a Multi-Institutional Study That Included a Notable Proportion of Older African American Patients? (Alliance A171603)
Authors: Guerard Emily , Dodge Andrew B. , Le-Rademacher Jennifer G. , Kemeny M. Margaret , Ojelabi Michael , Sedrak Mina S. , Hopkins Judith , Shahrokni Armin , Harlos Elizabeth , Muss Hyman , Cohen Harvey Jay , Lafky Jacqueline , Sloan Jeff , Jatoi Aminah , Hurria Arti 
Published: April 2021

PURPOSE This study determined whether an electronic version of the geriatric assessment is feasible in a multi-institutional, diverse setting. METHODs Ten sites within the Alliance for Clinical Trials in Oncology participated. Patients who had active cancer or a history of cancer and were 65 years of age or older were eligible. The geriatric assessment was completed with an electronic data capture system that had been loaded onto iPads. Feasibility was defined a priori as completion in at least 70% of patients either with or without help. To enhance racial diversity, the original sample size was later changed and augmented by 50% with the intention of increasing enrollment of older minority patients. RESULTS A total of one hundred fifty-four patients were registered with a median age of 72 years (range, 65-91 years). Forty-three (28%) identified themselves as African American or Black. One hundred forty-one patients (92%) completed the electronic geriatric assessment. Feasibility was observed across all subgroups, regardless of race, education, performance status, comorbidities, and cognition; 124 patients (81%) completed the geriatric assessment without help. Reasons for not completing the geriatric assessment are as follows: clinic visit did not occur (n = 6), no iPad connection to the Internet (n = 3), patient declined (n = 2), prolonged hospitalization (n = 1), and patient died (n = 1). Reasons for needing help, as reported by study personnel, were as follows: the patient preferred that research personnel ask the questions (n = 9), vision problem (n = 3), lack of comfort with the iPad (n = 2), questions were not clear (n = 1), less proficient in English (n = 1), and challenge in pressing the green button to go to the next question (n = 1). CONCLUSION The electronic geriatric assessment is feasible in a multi-institutional setting that includes a notable proportion of African American or Black patients.
Protocol for a scoping review of measurement of sleep in mild cognitive impairment and early dementia
Authors: Blackman Jonathan , Morrison Hamish , Harding Sam , Lloyd Katherine , Coulthard Elizabeth 
Published: April 2021

Background: Sleep abnormalities are increasingly recognised to emerge early in dementia, at or before the Mild Cognitive Impairment (MCI) phase. Abnormal sleep accelerates cognitive decline and may directly contribute to pathophysiology. Its accurate measurement is therefore crucial, firstly to characterise sleep abnormalities in early disease potentially facilitating earlier identification of those at risk of dementia and secondly to test sleep intervention efficacy. However, it is our a priori hypothesis that sleep outcomes are reported heterogeneously inhibiting side-by-side comparison of study findings. As a translational step towards informing choice and decisions on optimal measures, this scoping review will describe measurement tools utilised and sleep parameters currently reported in early dementia and MCI. Methods: This scoping review follows the Joanna Briggs Institute Manual for Evidence Synthesis for Scoping Reviews. The search strategy consists of an electronic search of the CINAHL Plus, Embase, Medline, Psychinfo and British Nursing Index databases and date limited to articles published from 2000. Search results will be merged using reference management software and duplicates removed. 10% of returned titles and abstracts will be checked by each reviewing member to ensure continuity of decision making. Full-texts will be reviewed by at least two reviewers with discrepancies resolved by whole team consensus. A PRISMA flow diagram will document the selection process. Extracted data will be analysed and reported narratively. Discussion: This scoping review will identify which sleep parameters are reported and the means by which they are measured in people with MCI or early dementia. We intend to explore differences in reporting practice within group subsets, e.g. by dementia and study subtype. Ethics and dissemination: Ethical approval is not required due to absence of human participants. Results will be published in a peer-reviewed journal and presented at relevant academic conferences. The search strategy will be made available publicly for transparency.
The Avon Longitudinal Study of Parents and Children - A resource for COVID-19 research: Generation 2 questionnaire data capture May-July 2020
Authors: Smith Daniel , Northstone Kate , Bowring Claire , Wells Nicholas , Crawford Michael , Pearson Rebecca M. , Thomas Amy , Brooks-Pollock Ellen , Lawlor Deborah A. , Timpson Nicholas John 
Published: April 2021

The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective population-based cohort study which recruited pregnant women in 1990-1992 from the Bristol area (UK). ALSPAC has followed these women, their partners (Generation 0; G0) and their offspring (Generation 1; G1) ever since. From 2012, ALSPAC has identified G1 participants who were pregnant (or their partner was) or had become parents, and enrolled them, their partners, and children in the ALSPAC-Generation 2 (ALSPAC-G2) study, providing a unique multi-generational cohort. At present, approximately 1,100 G2 children (excluding thosein utero) from 810 G1 participants have been enrolled.In response to the COVID-19 pandemic, ALSPAC rapidly deployed two online questionnaires; one during the initial lockdown phase in 2020 (9thApril-15thMay), and another when national lockdown restrictions were eased (26thMay-5thJuly). As part of this second questionnaire, G1 parents completed a questionnaire about each of their G2 children. This covered: parental reports of children’s feelings and behaviour since lockdown, school attendance, contact patterns, and health. A total of 289 G1 participants completed this questionnaire on behalf of 411 G2 children.This COVID-19 G2 questionnaire data can be combined with pre-pandemic ALSPAC-G2 data, plus ALSPAC-G1 and -G0 data, to understand how children’s health and behaviour has been affected by the pandemic and its management. Data from this questionnaire will be complemented with linkage to health records and results of biological testing as they become available. Prospective studies are necessary to understand the impact of this pandemic on children’s health and development, yet few relevant studies exist; this resource will aid these efforts.Data has been released as: 1) a freely-available dataset containing participant responses with key sociodemographic variables; and 2) an ALSPAC-held dataset which can be combined with existing ALSPAC data, enabling bespoke research across all areas supported by the study.