bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐dose vitamin D supplementation in patients with severe acute respiratory syndrome coronavirus 2 pneumonia hospitalized in a polyvalent intensive care unit: A retrospective cohort study
Authors: Vasconcelos Mafalda , Rodrigues Bárbara Sucena , Gonçalves Ana 
Published: February 2025

AbstractBackground and AimsThe health benefits of vitamin D are far beyond bone mineral metabolism. Vitamin D has immunomodulator and anti‐inflammatory properties and its role in critically ill patients is controversial. The purpose of the study is to understand whether high doses of vitamin D supplementation are beneficial in patients with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pneumonia hospitalized in a polyvalent intensive care unit (ICU) and correlate to all‐cause mortality, need for invasive mechanical ventilation, and duration of hospitalization.MethodsA retrospective study was conducted at a single polyvalent ICU, comparing patients supplemented with vitamin D with nonsupplemented patients. Eligible participants were adults with SARS‐CoV‐2 pneumonia admitted in this unit between April 14, 2020, and October 31, 2020. Demographic and clinical characteristics, comorbidities, and disease‐related outcomes were extracted from electronic medical records.ResultsNo statistically significant differences were observed between the groups in terms of need for invasive mechanical ventilation or duration of hospitalization. Supplementation with vitamin D was associated with lower all‐cause ICU, intrahospital, and total mortality.ConclusionHigh‐dose vitamin D supplementation was associated with a reduction of mortality in patients with severe SARS‐CoV‐2 pneumonia. Randomized clinical trials are needed to confirm these findings and to assess the optimal dosage of supplementation.
Investigating conservation performance payments alongside human–wildlife conflicts: The Swedish lynx and wolverine protection policies
Authors: Kaiser Josef , Hahn Thomas , Krueger Tobias , Haase Dagmar 
Published: February 2025

Abstract

Conservation performance payments are becoming an increasingly popular instrument to tackle human–wildlife conflicts. In Sweden, Sámi communities practicing reindeer husbandry receive performance payments as compensation for reindeer losses caused by lynxes and wolverines. This study examines the challenges and conflicts associated with the Conservation Performance payment scheme and aims to understand its effectiveness.

We carried out a thematic analysis of challenges and conflicts using semi‐structured interviews with stakeholders associated with the payment scheme as the main source of evidence, supported by literature identified in a systematic review.

The results reveal a wicked conflict setting with a broad range of direct and indirect conflicts. Direct conflicts revolve around the following themes: (1) Uncertainty and mistrust regarding the annual number of lynx and wolverine family groups and the extent of reindeer losses caused by these predators; (2) Payments being too small to cover losses; (3) Large numbers of reindeer lost to predators in many communities and the related hunting regulations. Indirect conflicts are linked to cumulative effects, such as the negative effects of forestry and mining projects on reindeer husbandry, a lack of comprehensive environmental policies, and the perceived lack of respect for reindeer herding as a culturally significant livelihood.

We argue that conflicts regarding uncertainties in predator and reindeer loss numbers in particular rather mask broader underlying conflicts.

Policy implications: We suggest that high predator‐caused reindeer losses in combination with indirect conflicts hampers the successful implementation of the program. Nevertheless, all interviewees appreciated the basic design of the program and its potential. However, realizing this potential requires acknowledging the wickedness of human–wildlife conflicts and adequately addressing long‐standing ecological and socio‐cultural root conflicts by developing comprehensive, cross‐sectoral, and inclusive conservation policies.

Read the free Plain Language Summary for this article on the Journal blog.
Multi‐modal assessment of recycled polyethylene terephthalate composites in additive manufacturing: The role of carbon fiber
Authors: Charkieh Ahmad Shawki , Zhu Yifan , Huysman Sofie , Polyzos Efstratios , Quaak Astrid , Pien Nele , Carpentier Nathan , Boone Matthieu N. , Pyl Lincy 
Published: February 2025

AbstractWith the growing interest in sustainable manufacturing, 3D printing with recycled Polyethylene Terephthalate (rPET) offers an innovative approach to upcycling waste. This study explores the potential of combining rPET with milled short carbon fibers and polymer chain extenders to produce high‐performance 3D printing filaments through melt extrusion. Filaments containing 5% and 10% carbon fiber, with and without sizing, along with a polymer chain extender, were investigated to enhance viscosity and material properties of rPET. Thermal analysis techniques evaluated the material's thermal stability and transitions, assessing the degradation temperature and calorimetric properties including glass transition and melting temperatures, while the measured carbon fiber content closely matched the theoretical content. Tensile testing of unidirectionally printed samples showed promising mechanical properties. X‐ray micro‐computed tomography assessed fiber length in extruded filaments, comparing it with the target length set during manufacturing, showing agreement. Scanning electron microscopy examined fracture and side surfaces, revealing governing failure mechanisms and defects, attributed to filament production and composition. This study highlights the synergistic role of carbon fiber sizing and chain extenders in enhancing tensile modulus, while improving overall consistency and quality of extruded filaments. It presents a groundbreaking pathway for sustainable, high‐performance additive manufacturing.Highlights
Investigated the synergistic effect of CF sizing and chain extenders in rPET.
Melt extrusion achieved 10% CF with excellent fiber alignment and integrity.
Additives enhanced thermal stability, crystallization, and adhesion.
SEM and Micro‐CT revealed improved fiber‐matrix bonding and fewer defects.
Tensile modulus doubled through synergy of CF sizing and chain extenders.
The Impact of School‐Based Personnel Delivered Coaching and Performance Feedback on Elementary Teachers' Use of Behavior Specific Praise
Authors: Ellis Kaci , Gage Nicholas A. , MacSuga‐Gage Ashley S. , Schmidt Carla , Lane Holly , Serpahine Ann 
Published: February 2025

ABSTRACTPerformance feedback has been shown to improve teachers' classroom management skills. Typically, a researcher provides the performance feedback, not school‐based personnel. Therefore, we investigated the effects of performance feedback on classroom management skills when the feedback is delivered by school‐based personnel. We used a concurrent multiple baseline design across participants to examine the effects of visual performance feedback provided by a school behavior resource teacher on four teachers' use of behavior specific praise. One White behavior support teacher, two White teachers, and two Black teachers, all with more than 5 years of teaching experience participated in the study. We used visual analysis and Tau‐U single‐case design effect sizes to evaluate the multiple baseline design. Results indicate a functional relation between visual performance feedback provided by a school behavior resource teacher and teachers' increased use of behavior specific praise The results suggest that school‐based personnel can be trained in data collection, brief coaching sessions, and implementation of visual performance feedback to support teachers in increasing their use of behavior‐specific praise. This study provides evidence that school‐based personnel can help teachers increase their use of BSP during instruction.
A Meta‐Analysis on the Effects of Peer Tutoring on Emergent Bilinguals’ Academic Achievement
Authors: Romero Monica E. , Burns Matthew K. , Wan Hoi Ting , Abdelnaby Heba , Crawford Tiffany J. 
Published: February 2025

ABSTRACTThis meta‐analysis investigated the effects of peer tutoring interventions on the academic achievement of Emergent Bilingual (EB) students from preschool through Grade 12. Fourteen studies, including peer‐reviewed journal articles and unpublished dissertations published between 2010 and 2021, were analyzed based on study characteristics, student variables, and intervention characteristics. The findings indicate that peer tutoring yielded a moderate effect size (g = 0.58, 95% CI = 0.22–0.94) on EBs’ academic outcomes. The majority of studies focused on elementary‐aged students, with significantly fewer studies addressing preschool or secondary‐level EBs. Nearly all studies involved Spanish‐speaking students (n = 14), and most targeted reading outcomes demonstrated a moderate effect size (g = 0.62, 95% CI = 0.24–1.00). Only a limited number of effects came from studies involving EBs with disabilities. These findings underscore the potential of peer tutoring to support reading development among EBs while highlighting critical research gaps, particularly at the secondary level and in core content areas such as mathematics. Implications for practice and directions for future research are discussed.
Refinement and curation of homologous groups facilitated by structure prediction
Authors: Schaeffer Richard Dustin , Pei Jimin , Zhang Jing , Cong Qian , Grishin Nick V. 
Published: February 2025

AbstractDomain classification of protein predictions released in the AlphaFold Database (AFDB) has been a recent focus of the Evolutionary Classification of protein Domains (ECOD). Although a primary focus of our recent work has been the partition and assignment of domains from these predictions, we here show how these diverse predictions can be used to examine the reference domain set more closely. Using results from DPAM, our AlphaFold‐specific domain parsing algorithm, we examine hierarchical groupings that share significant levels of homologous links, both between groups that were not previously assessed to be definitively homologous and between groups that were not previously observed to share significant homologous links. Combined with manual analysis, these large datasets of structural and sequence similarities allow us to merge homologous groups in multiple cases which we detail within. These domains tend to be families of domains from families that are either small, previously had few experimental representatives, or had unknown function. The exception to this is the chromodomains, a large homologous group which were increased from “possibly homologous” to “definitely homologous” to increase the consistency of ECOD based their strong homologous links to the SH3 domains.
Pioneering Mass Spectrometry: A Tribute to My Mentor Jean‐François Muller and His Enduring Legacy
Authors: Frache Gilles 
Published: February 2025

ABSTRACTProfessor Jean‐François Muller, a distinguished figure in the field of mass spectrometry, made significant contributions to the advancement of analytical chemistry and its applications. As the founding director of the Laboratory of Mass Spectrometry and Laser Chemistry at the University of Metz, Muller played a pivotal role in establishing Metz as a leading center for mass spectrometry research. His pioneering work, particularly in the development of matrix‐assisted laser desorption/ionization (MALDI) instrumentation and Fourier transform ion cyclotron resonance mass Spectrometry (FTICR MS), has had a profound impact on various scientific disciplines. This article commemorates Professor Muller's illustrious career and highlights his collaborative efforts with industrial partners such as Total, which led to groundbreaking advancements in MS analysis. I will delve into the key findings of my thesis which focused on instrumental developments for MALDI analysis and imaging, as well as personal reminiscences and the impact of his inspiring mentorship.
Algebraic rates of stability for front-type modulated waves in Ginzburg–Landau equations
Authors: Beyn Wolf-Jürgen , Döding Christian 
Published: February 2025

Abstract
We consider the stability of front-type modulated waves in the complex Ginzburg–Landau equation (CGL). The waves occur in the bistable regime (e.g., of the quintic CGL) and connect the zero state to a spatially homogenous state oscillating in time. For initial perturbations that decay at a certain algebraic rate, we prove convergence to the wave with asymptotic phase. The convergence holds in algebraically weighted Sobolev norms and with an algebraic rate in time, where the asymptotic phase is approached by one order less than the profile. On the technical side, we use the theory of exponential trichotomies to separate the spatial modes into growing, weakly decaying, and strongly decaying ones. This allows us to derive resolvent and semigroup estimates in weighted Sobolev norms and to close the argument with a Gronwall lemma involving algebraic weights.
Scanogram leg length measurement after total hip arthroplasty: not all landmarks are created equal
Authors: Le Brian T. N. , Bourgeault-Gagnon Yoan , Lyons Matthew C. , McCaffrey Samuel L. , Salmon Lucy J. , O’Sullivan Michael D. 
Published: February 2025

Abstract

Objective
To compare the magnitude of post-arthroplasty leg length discrepancy (LLD) and incidence of clinically significant LLD measured on CT scanogram using a commonly used measurement method (from the acetabular apex to tibial plafond) to an alternative technique avoiding the use of the acetabular prosthesis as a landmark and to assess inter-observer and intra-rater reliability of the new technique.

Materials and methods
In this retrospective study, post-arthroplasty LLD measurements were conducted in 100 hips by two interpreters on CT scanogram scout views from the acetabular apex to the tibial plafond (AA-TP) and the inter-teardrop line to the tibial plafond (IT-TP). Aggregate means and proportions of clinically relevant LLD (≥ 10 mm) were compared between methods. Inter-rater reliability was calculated, and both interpreters repeated measurements on ten randomly selected patients to calculate intra-rater reliability.

Results
The commonly used AA-TP technique overestimated LLD by 3.7 mm compared to the IT-TP technique. The odds of LLD measurement exceeding the clinically significant threshold of 10 mm were 3.8 times higher when using the AA-TP technique. Excellent inter-rater (ICC 0.984, 0.958) and intra-rater reliability (ICC > 0.9) were found for both techniques.

Conclusion
CT scanogram measurements from the acetabular apex to the tibial plafond often overestimate operative limb length due to reference landmarks in different axial planes. Measurements from the inter-teardrop line to the tibial plafond yield significantly lower LLD values, possibly reflecting actual limb length better. The authors recommend using the inter-teardrop line and tibial plafond as reference landmarks to improve LLD assessment accuracy post-arthroplasty.
Preparation of non-toxic green slippery liquid infused surfaces based on electrospun fiber with anti-algae and anti-bacterial properties
Authors: Dinc Sena Kardelen , Caglar Busra Nur , Birlik Demirel Gokcen , San Keskin Nalan Oya 
Published: February 2025

Abstract
Microbial attachment is a problem of vital importance and economic significance, particularly in marine environments. Slippery Liquid Infused Surfaces (SLIPS) have attracted considerable interest as a solution to this challenge. In the present study, we hypothesized that Saint John's Wort Oil (SJWO) could provide an eco-friendly alternative to synthetic oils, combating marine microbial attachment with non-toxic chemicals. We developed a hydrophobic electrospun porous cellulose acetate fiber layer, coated with silica nanoparticles (SiO2NPs), and infused with SJWO. The optimization process involved measuring sliding velocity, the number of SiO2NP layers, the amount of lubricant, and the infusion time. The optimal configuration demonstrated a sliding velocity of 0.31 cm/s on a 10° slope. Antibacterial tests revealed that the SLIPS reduced bacterial attachment of Pseudomonas aeruginosa from 1.67 ± 0.03 × 106 CFU/mL on glass substrates to 2.85 ± 0.07 × 105 CFU/mL for SLIPS. Similarly, the anti-algae performance against Chlorella sp. showed a significant reduction in optical density from 0.92 ± 0.01 for glass substrates to 0.19 ± 0.01 for SLIPS, and chlorophyll content was reduced from 7.24 ± 0.19 µg/mL to 3.70 ± 0.77 µg/mL. The findings indicate that SJWO-infused SLIPS provide a robust and effective method for reducing microbial attachment.
Tinnitus is not associated with cardiovascular risk factors or mortality in the Gutenberg Health Study
Authors: Hahad Omar , Hackenberg Berit , Döge Julia , Bahr-Hamm Katharina , Kerahrodi Jasmin Ghaemi , Tüscher Oliver , Michal Matthias , Kontohow-Beckers Konstantin , Schuster Alexander K. , Schmidtmann Irene , Lackner Karl J. , Schattenberg Jörn M. , Konstantinides Stavros , Wild Philipp S. , Münzel Thomas 
Published: February 2025

Abstract

Background and aims
Tinnitus, characterized by the conscious perception of sound without external acoustic stimulation, presents a multifaceted challenge. Recent research suggests a potential association between tinnitus and cardiovascular health. To elucidate these associations further, we examined the prevalence of tinnitus alongside its distress levels and their associations with cardiovascular risk factors, diseases, and risk of death within a general population cohort.

Methods and results
This study analyzed data from the prospective Gutenberg Health Study (GHS), a population-based cohort of 15,010 individuals aged 35–74, who underwent baseline assessments from 2007 to 2012. We focused on the 10-year follow-up (2017–2020) of the GHS, including otologic testing with 8539 subjects, of whom 2387 (28%) reported tinnitus, allowing for a comprehensive cross-sectional and prospective analysis. Participants completed a questionnaire on hearing-related symptoms, including tinnitus presence (“Do you suffer from ringing in the ears (tinnitus)?” yes/no) and distress (“How much do you feel bothered by it?”), rated on a six-point scale from 0 (“not bothersome”) to 5 (“very bothersome”). Outcomes were assessed based on observed prevalent cardiovascular conditions (i.e., cardiovascular risk factors and diseases) and deaths. Additionally, calculated cardiovascular risk was assessed using the SCORE2 algorithm. Significant differences in baseline characteristics emerged between participants with and without tinnitus, with the former exhibiting advanced age, male predominance, and a higher prevalence of cardiovascular risk factors and diseases. Tinnitus displayed associations with various prevalent cardiovascular diseases including atrial fibrillation (odds ratio 1.48, 95% confidence interval 1.11–1.96), peripheral artery disease (1.43, 1.05–1.95), coronary artery disease (1.49, 1.09–2.04), and any cardiovascular disease (1.31, 1.11–1.56), persisting even after adjustments for demographic, socioeconomic, and cardiovascular risk factors. While crude associations with several prevalent cardiovascular risk factors were observed, these associations diminished upon comprehensive adjustment. Tinnitus presence was associated with elevated 10-year cardiovascular disease risk (incidence rate ratio 1.11, 1.09–1.13), as indicated by higher SCORE 2 values, yet did not predict all-cause mortality risk.

Conclusions
In the present study, tinnitus was associated with prevalent cardiovascular disease. However, no association with cardiovascular risk factors and mortality was found.
Pseudotumor following total hip arthroplasty: experience of a tertiary referral center and proposal of the new “PCS” classification system
Authors: Stimolo Davide , Muratori Francesco , Cucurullo Lorenzo , Scoccianti Guido , Innocenti Matteo , Campanacci Domenico Andrea 
Published: February 2025

Abstract

Introduction
This study summarizes outcomes in treating pseudotumors of the hip at a tertiary referral center and introduces a classification system to aid treatment decisions and enhance communication among providers.

Materials and methods
We collected data from 39 patients who underwent surgery for hip pseudotumor, analyzing implant failures based on patient history, revision reasons, bearing surface type, mass location and size, bone loss, revision type, and whether it was single- or two-stage. We introduce the PCS classification: ‘P’ for Pseudotumor (with ‘s’ for symptomatic, ‘e/I’ for intra/extrapelvic location, and ‘m’ for high Chromium/Cobalt levels), ‘C’ for implant status, and ‘S’ for bone loss extent. In 37 patients, we evaluated Cohen’s kappa coefficient to evaluate interobserver reliability.

Results
Twenty (51.2%) patients were female, with a mean age of 71 years (range 36–89; σ 12.11); the mean follow-up duration was 54.43 months (range 12.2–128.3). The average size of the pseudotumor was 13.10 cm (range 3.3–37.2; σ 7.11) with 61.5% exhibiting extra-pelvic localization only. Bearing surfaces were MoM in 27 patients (69.2%). Single-stage revision surgery was performed in 87.1% of patients. There were 7 (17.9%) implant failures. No significant differences in failure rates were observed based on considered parameters. The agreement following Cohen’s coefficient for the combined PCS classification was k = 0.43. Moderate to almost perfect agreement was obtained for parameter P and S, with k = 0.48 for parameter C.

Conclusion
No correlation was found between failures and analyzed characteristics. Our classification assesses clinical scenarios and stratifies surgical complexity for indication purposes. While interobserver agreement varies with parameter C, it is consistent with parameters P and S.
Inverse design of spinodoid structures using Bayesian optimization
Authors: Raßloff Alexander , Seibert Paul , Kalina Karl A. , Kästner Markus 
Published: February 2025

Abstract
Tailoring materials to achieve a desired behavior in specific applications is of significant scientific and industrial interest as design of materials is a key driver to innovation. Overcoming the rather slow and expertise-bound traditional forward approaches of trial and error, inverse design is attracting substantial attention. Targeting a property, the design model proposes a candidate structure with the desired property. This concept can be particularly well applied to the field of architected materials as their structures can be directly tuned. The bone-like spinodoid materials are a specific class of architected materials. They are of considerable interest thanks to their non-periodicity, smoothness, and low-dimensional statistical description. Previous work successfully employed machine learning (ML) models for inverse design. The amount of data necessary for most ML approaches poses a severe obstacle for broader application, especially in the context of inelasticity. That is why we propose an inverse-design approach based on Bayesian optimization to operate in the small-data regime. Necessitating substantially less data, a small initial data set is iteratively augmented by in silico generated data until a structure with the targeted properties is found. The application to the inverse design of spinodoid structures of desired elastic properties demonstrates the framework’s potential for paving the way for advance in inverse design.