bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical and echographic signs of acute kidney injury in premature babies born with very low and extremely low body weight
Authors: Zakharova I. N. , Sugian N. G. 
Published: November 2021

Introduction. One of the urgent issues in the first stage of nursing premature infants is acute kidney injury. The incidence of neonatal acute kidney injury in developing countries is 3.9/1000 live births, with 34.5/1000 among neonatal intensive care patients.The aim of the study was to establish echographic signs of acute kidney injury in deeply premature infants in the neonatal period.Materials and methods. 24 children with clinical and laboratory signs of acute kidney injury “AKI+” and 76 children without signs of acute kidney injury “AKI-“. All the children included in the study were born with a body weight of less than 1500 g and a gestation period of less than 32 weeks and were in the neonatal intensive care unit. To clarify the nature of the detected changes, a scientific analysis of the results of pathoanatomic studies of 55 deceased preterm infants was carried out.Results. In all children from the “AKI+” group, there was a pronounced diffuse-uneven increase in the echogenicity of the parenchyma, there was a depletion of the vascular pattern in the subcapsular zone and/or in the cortical layer of the parenchyma, in 25% of patients on the 5th-15th day of life, anechogenic formations without signs of blood flow, with a diameter of 1-3 mm in the cortical layer were noted. The changes had a bilateral nature of the lesion, with further observation they were gradually reduced and by 3 ± 2 months of life they were not determined during ultrasound of the kidneys.Discussion. Acute kidney injury is an urgent problem of preterm infants born with very low and extremely low body weight. The article presents the results of ultrasound examination of the kidneys in comparison with clinical and laboratory indicators and the results of pathomorphological studies. As a result of the study, the most characteristic ultrasound signs of acute kidney injury were identified, which are an uneven diffuse increase in the echogenicity of the renal parenchyma, small anechoic avascular inclusions (cysts) of the parenchyma, depletion of renal blood flow.Conclusions. Renal ultrasonography is an informative method, but echographic changes may be labile depending on the clinical course of the disease, and the absence of anechogenic masses in the parenchyma may be due to technical limitations of the ultrasonography method. It requires further monitoring and continued vigilance of the pediatrician and pediatric nephrologist.
Use of topical reparative creams for sensitive and atopic skin in children
Authors: Kovalevskaya-Kucheryavenko T. V. 
Published: November 2021

In recent decades, there has been a significant increase in allergy pathology among the pediatric population. One in five children at a pediatrician’s consultation has an allergic disease or has a history of allergy, or manifestations of an atopic constitution. Also, in recent years, the term «sensitive skin» has become increasingly common in the medical literature. It is an independent syndrome that manifests itself in two forms: objective, in which the syndrome clinic is observed in parallel with the skin disease, and subjective when the manifestations of the syndrome occur in healthy skin. The main manifestations of sensitive skin syndrome are burning, itching, and tingling sensations, as well as thickening and dryness of the skin in response to environmental factors. Often, sensitive skin is associated with the most common skin pathology of childhood - atopic dermatitis. This association obliges the use of combined external therapy in practice. Topical glucocorticosteroids in the form of monotherapy or combination with antibacterial and/or antifungal agents are designed to control the dynamics of inflammation and lead to the achievement and prolongation of remission. However, the combination of anti-inflammatory agents with reparative creams is more effective because it enhances the healing processes of the damaged skin.The article describes clinical cases of skin treatment in children with a history of allergies, atopic dermatitis, and sensitive skin syndrome. The therapy used restorative agents of dermocosmetics in the example of reparative cream. Clinical examples showed high efficacy of the combination of topical anti-inflammatory agents and reparative cream. This combination led to a more rapid reduction of dryness and itching, the intensity of inflammation, contributed to the rapid recovery of damaged skin, increased adherence to treatment by patients and patient’s parents.
Features of neurological and psychomotoral development of premature children born by IVF and naturally
Authors: Druzhrnina N. A. , Merzlyakova D. R. , Akhmetshin R. Z. , Khafizova N. R. , Shiryaeva G. P. , Shagarova S. V. 
Published: November 2021

Introduction.The use of in vitro fertilization methods plays an important role in overcoming the childlessness of families, but they must be combined with the success of nursing premature newborns to increase the effectiveness of assisted reproductive technologies. Children with very or extremely low body weight are at risk of increased rates of infant mortality and disability. The study of the state of health and the analysis of the psychomotor/neurological status of such children is extremely important due to the study of the possibilities of reducing the frequency of negative outcomes.Aim.A study during the first 3 years of neurological/psychomotor development in premature infants diagnosed with extremely low/very low body weight, born as a result of in vitro fertilization and naturally.Materials and methods.Studies of neurological/psychomotor development in premature infants have been carried out. The study included 189 infants diagnosed with prematurity at birth. The studies were carried out on the basis of the intensive care unit and the department of prematurity and neonatal pathology at the Republican Children’s Clinical Hospital (Ufa). Then, for 3 years, regular observation was carried out in the follow-up room in the same institution. Dynamic assessment of neurological and psychomotor status was performed using the Clinical Adaptive Test and Clinical linguistic and auditory milestone scales, as well as Gross Motor testing.Results and discussion. It was found that the incidence of neurological morbidity related to developmental delay is significantly higher in children born as a result of in vitro fertilization than in those conceived naturally. Thus, the number of children lagging behind in speech development at the age of up to 1 year is 59.1/59.6 and 52.1/52.3% when diagnosed with very low and extremely low body weight.Conclusion.The dynamics of the average coefficient of speech development in children conceived artificially did not reach (less than 75) normal values by the age of 3, and in the control group, the coefficient of speech development was normalized. There is no significant difference between very low and extremely low body weight children.
A case report of Potter’s syndrome in a newborn
Authors: Shidakov I. H. , Shavtikova A. T. , Dzhibabova F. A. 
Published: November 2021

Introduction. Potter’s sequence is a very rare and severe syndromic complex that includes congenital kidney defects leading to oligohydramnios, lung hypoplasia and structural skeletal disorders. Clinical case presentation: observation of a boy born from the 5th pregnancy to the mother at 37 weeks. Antenatally, the fetus was found to have bilateral renal and urinary bladder agenesis, malformations of the limbs, but the parents refused to terminate the pregnancy. After birth, the child was diagnosed with Potter’s syndrome with severe hypoplasia of the lungs, which required mechanical ventilation. In 2 hours after birth, the child developed a tension pneumothorax, which was arrested by performing drainage of the pleural cavity. During the day, the patient received complex treatment in the intensive care unit, despite which, by the 2nd day of life, the death of the child occurred. Currently, there are no guidelines for the treatment of Potter syndrome with proven positive long-term outcomes.Discussion. Children with Potter syndrome do not have the same set of symptoms, but they develop a chain of events leading to a common ultimate result - decreased amount of amniotic fluid. Abnormalities leading to oligohydramnios may include severe hypoplasia, dysplasia, polycystic, obstructive uropathy or renal agenesis. In most cases, the disease occurs sporadically, but there are also forms with transmission of the disorder through successive generations: autosomal dominant or recessive inheritance of polycystic disease, hereditary renal dysplasia caused by mutations in RET, UPK3A genes and other chromosomal abnormalities.Conclusion. Potter syndrome is a set of severe syndromes manifested by abnormalities in the development of kidneys, oligohydramnios, leading to lung hypoplasia, skeletal disorders and other congenital anomalies. The severity of congenital defects included in the set depends on the time periods when oligohydramnios occurred. Despite the availability of experimental therapies, the disease is now considered to be fatal.
Application of hypertonic saline in children with acute bronchitis
Authors: Denisova A. R. , Kolosova N. G. , Grebeneva I. V. , Denisova V. D. , Glukhova M. V. , Lurie E. V. 
Published: November 2021

Introduction. Cough is the most common manifestation of respiratory infections of the upper and lower respiratory tract and indicates impaired mucociliary clearance. The cause of cough must be determined to choose the management tactics for children with cough. The most commonly used mucoactive drugs liquefy sputum as a result of a direct action of the components on the tracheobronchial secretion and/or mucosa of the respiratory tract. Given the mucoactive effect of hypertonic salines, we conducted an open clinical study of the effectiveness of 3% hypertonic saline with hyaluronic acid in acute bronchitis in children.Aim of the study. To evaluate the clinical effect of 3% hypertonic saline with hyaluronic acid in acute bronchitis in children.Materials and methods. Clinical efficacy and safety of 3% hypertonic saline with hyaluronic acid in 50 patients aged 3 to 12 years old with acute bronchitis were evaluated in the dynamics on the 1st, 3rd, 7th days of treatment with the score assessment of symptoms (cough, stuffy nose, auscultation data) and an indication of adverse events (if any).Results. Improvement of condition was noted in most patients by the 3rd day of therapy (mean score 1.88 ± 0.3), temperature normalized in all patients, manifestations of rhinitis decreased. By the 5th day of treatment, the intensity of cough did not exceed 1 point in all patients (0.7 ± 0.14 points). According to the patient’s diary data, by the 7th day of treatment 74% of the children had no cough. On the 7th day of treatment, some children had a rare residual cough (0.36 ± 0.06 points), minor rhinitis (0.16 ± 0.1 points). No rales were heard in the lungs in all patients, rigid breathing was heard in 11 patients (mean score 0.22 ± 0.05).Conclusions. The conducted study demonstrated that 3% hypertonic saline with hyaluronic acid is an effective drug in the treatment of cough in acute bronchitis in children.
The microorganism-plant system for remediation of soil exposed to coal mining
Authors: Drozdova Margarita , Pozdnyakova Anna , Osintseva Maria , Burova Nadezhda , Minina Varvara 
Published: November 2021

Introduction. Coal mining causes a radical transformation of the soil cover. Research is required into modern methods and complementary technologies for monitoring technogenic landscapes and their remediation. Our study aimed to assess soil and rhizosphere microorganisms and their potential uses for the remediation of technogenic soils in Russian coal regions.
Study objects and methods. We reviewed scientific articles published over the past five years, as well as those cited in Scopus and Web of Science.
Results and discussion. Areas lying in the vicinity of coal mines and coal transportation lines are exposed to heavy metal contamination. We studied the application of soil remediation technologies that use sorbents from environmentally friendly natural materials as immobilizers of toxic elements and compounds. Mycorrhizal symbionts are used for soil decontamination, such as arbuscular mycorrhiza with characteristic morphological structures in root cortex cells and some mycotallia in the form of arbuscules or vesicles. Highly important are Gram-negative proteobacteria (Agrobacterium, Azospirillum, Azotobacter, Burkholderia, Bradyrizobium, Enterobacter, Pseudomonas, Klebsiella, Rizobium), Gram-positive bacteria (Bacillus, Brevibacillus, Paenibacillus), and Grampositive actinomycetes (Rhodococcus, Streptomyces, Arhtrobacter). They produce phytohormones, vitamins, and bioactive substances, stimulating plant growth. Also, they reduce the phytopathogenicity of dangerous diseases and harmfulness of insects. Finally, they increase the soil’s tolerance to salinity, drought, and oxidative stress. Mycorrhizal chains enable the transport and exchange of various substances, including mineral forms of nitrogen, phosphorus, and organic forms of C3 and C4 plants. Microorganisms contribute to the removal of toxic elements by absorbing, precipitating or accumulating them both inside the cells and in the extracellular space.
Conclusion. Our review of scientific literature identified the sources of pollution of natural, agrogenic, and technogenic landscapes. We revealed the effects of toxic pollutants on the state and functioning of living systems: plants, animals, and microorganisms. Finally, we gave examples of modern methods used to remediate degraded landscapes and reclaim disturbed lands, including the latest technologies based on the integration of plants and microorganisms.
Effect of the coexistence of SO32− and PO43− on the adsorption performance of zeolite-loaded FeOOH@ZnO for S2−
Authors: Li Fen , Li Youjing , Ge Baocai , Hu Jinguang , Yu Cailian , Meng Fanzhu 
Published: November 2021

AbstractThe present study deals with the synthesis of zeolite-loaded FeOOH@ZnO by hydrothermal method and investigates the effects of coexisting SO32− and PO43− ions in the aqueous solution on the adsorption performance for S2−. The results showed that the HNO3-modified zeolite loaded with FeOOH@ZnO (FeOOH@ZnO/HZ) resulted in a maximum S2− removal rate of ≈98%. The adsorbent's performance on removing S2− was significantly enhanced, compared with NaOH and ZnCl2-modified zeolites loaded with FeOOH@ZnO, and the adsorption was proved to be a heat-absorbing process. When SO32− and PO43− coexisted with S2−, SO32− and PO43− had a significant influence on the adsorption properties of FeOOH@ZnO/HZ. When three ions of S2−, SO32− and PO43− were present simultaneously, the adsorption performance of FeOOH@ZnO/HZ on S2− was further, and the removal rate dropped to about 80%. Moreover, FeOOH@ZnO/HZ also adsorbed PO43− and SO32− in the system containing multiple ions, but the adsorption rates of PO43− and SO32− were much lower than S2−. This indicated that the adsorption of S2− in the presence of FeOOH@ZnO/HZ dominates under competitive conditions.
Implementation of eHealth to Support Assessment and Decision-making for Residents With Dementia in Long-term Care: Systematic Review
Authors: Gillam Juliet , Davies Nathan , Aworinde Jesutofunmi , Yorganci Emel , Anderson Janet E , Evans Catherine 
Published: November 2021

BackgroundAs dementia progresses, symptoms and concerns increase, causing considerable distress for the person and their caregiver. The integration of care between care homes and health care services is vital to meet increasing care needs and maintain quality of life. However, care home access to high-quality health care is inequitable. eHealth can facilitate this by supporting remote specialist input on care processes, such as clinical assessment and decision-making, and streamlining care on site. How to best implement eHealth in the care home setting is unclear.ObjectiveThe aim of this review was to identify the key factors that influence the implementation of eHealth for people living with dementia in long-term care.MethodsA systematic search of Embase, PsycINFO, MEDLINE, and CINAHL was conducted to identify studies published between 2000 and 2020. Studies were eligible if they focused on eHealth interventions to improve treatment and care assessment or decision-making for residents with dementia in care homes. Data were thematically analyzed and deductively mapped onto the 6 constructs of the adapted Consolidated Framework for Implementation Research (CFIR). The results are presented as a narrative synthesis.ResultsA total of 29 studies were included, focusing on a variety of eHealth interventions, including remote video consultations and clinical decision support tools. Key factors that influenced eHealth implementation were identified across all 6 constructs of the CFIR. Most concerned the inner setting construct on requirements for implementation in the care home, such as providing a conducive learning climate, engaged leadership, and sufficient training and resources. A total of 4 novel subconstructs were identified to inform the implementation requirements to meet resident needs and engage end users.ConclusionsImplementing eHealth in care homes for people with dementia is multifactorial and complex, involving interaction between residents, staff, and organizations. It requires an emphasis on the needs of residents and the engagement of end users in the implementation process. A novel conceptual model of the key factors was developed and translated into 18 practical recommendations on the implementation of eHealth in long-term care to guide implementers or innovators in care homes. Successful implementation of eHealth is required to maximize uptake and drive improvements in integrated health and social care.
Effect of clinical Pilates training on balance and postural control in patients with Parkinson’s disease: a randomized controlled trial
Authors: Çoban Fahriye , Belgen Kaygısız Beliz , Selcuk Ferda 
Published: November 2021

Background:
Clinical pilates exercises have been shown to improve balance. Our study aims to compare effects of clinical Pilates and conventional physiotherapy exercises on balance and postural control in Parkinson’s disease patients.
Materials & methods:
Forty patients were randomly assigned into either clinical Pilates (CLP) or conventional physiotherapy (COP) group. Exercises were performed twice a week for 8 weeks. Balance, lower-extremity strength, fall risk and functional mobility were assessed at the beginning and end of the exercise period.
Results:
All measurements indicated significant increase in two groups (p < 0.05). Compared with the COP group, the CLP group showed significant improvement in dynamic balance values (p < 0.05).
Conclusion:
CLP was as effective as COP, with better dynamic balance results, and could be used in rehabilitation for patients with Parkinson’s disease.

Clinical trial registration number:
NCT04063605
.
Harnessing molasses as a low-cost carbon source for production of poly-hydroxy butyrate (PHB) using Burkholderia sp. B73 bacteria
Authors: RATNANINGRUM Diah - , ENDAH Een Sri , LISDIYANTI Puspita , PRIATNI Sri , SARASWATY Vienna 
Published: November 2021

Burkholderia sp. has been reported as a poly-hydroxy-butyrate (PHB) producer. PHB is a natural polyester class with a wide range of applications in foods, medicines, and biomedicines. However, the high production cost of PHB may limit its potential. Molasses, a by-product of the sugarcane industry available abundantly, may be used as an alternative carbon source of PHB production. In this research, we aimed to evaluate PHB production by Burkholderia sp. B73 in fermentation media using molasses as an alternative carbon source. Small-scale experiments were performed in Erlenmeyer flasks on a shaker at 150 rpm and 30 °C to evaluate the best initial C/N ratio for biomass accumulation and PHB production. A set of parameters including bacterial growth, dry cell weight, yield, and FTIR spectrum of PHB were observed. The results showed that molasses could be used to grow Burkholderia sp. B73 and the highest PHB production was obtained when a 20:1 C/N ratio of molasses was applied in the fermentation medium. In addition, when the initial pH was adjusted to 7.0, the highest PHB yield was also produced. More importantly, the use of molasses as a carbon source improved the PHB yield by nearly 2-fold compared with our previous report using a synthetic Ramsay’s minimal medium. In conclusion, the experiment results showed that molasses could be used as a low-cost carbon source for PHB production by Burkholderia sp. B73 bacteria.
Pembinaan Karakter Mahasiswa di Ma’had UIN Ar-Raniry Banda Aceh
Authors: Munita Putri 
Published: November 2021

One of the functions of education is to form the character of students. Character building is a system of inculcating character values ​​to students through competency achievement activities in accordance with the level of education. Character education at the institutional level leads to the formation of values ​​that underlie individual behavior applied in society. The problem that arises in this research lies in fostering student character so that it gives rise to several research questions such as: How to plan students’ character development at Ma'had UIN Ar-Raniry Banda Aceh in building student character, How is the implementation of the Ma'had UIN Ar-Raniry Banda Aceh program in fostering student character and what are the implications of the Ma'had UIN Ar-Raniry Banda Aceh program in fostering students’ character. The purpose of this study is to determine the efforts made by ustaz ustazah in planning student character development in Ma'had, to determine the implementation of the Ma'had UIN Ar-Raniry Banda Aceh program and to find out what are the implications of the Ma'had UIN Ar-Raniry Banda Aceh program. in building student character. The research method in this thesis uses qualitative research methods in the form of descriptive analysis. Data collection was carried out using observation, interview and documentation techniques. The results in this thesis research indicate that planning at the beginning of the program that students are required to live in a dormitory and the role of dorm supervisor is very important for students in the dormitory. They carry out disciplinary attitudes through congregational prayers, Implementation of the Ma'had program through the Tsaqafah Islamiyah program, the Tahsin program and the Dormitory program. The ma'had program is very beneficial for students, because undergoing activities in a dormitory is like living in an Islamic boarding school. Surely, it really helps them in doing good things, especially in worship to get closer to the Khaliq and many other positive things that students get during this program. They can manage their time in discipline.