bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pemanfaatan QR Code Dalam Pembuatan Karya Majalah Dinding Sebagai Sarana Literasi Digital
Authors: Imtiyaz Roniyah  , Syifani Nindya Nawangsari  , Arina Khalwa  , Oktavia Putri Anggraini  , Naila Jihan Ara  , Ahmad Khoirudin  , Nurul Farida  , Herdin Ferdiansyah  , Galuh Indah Zatadini  , Nurul Setyawati Handayani  
Published: January 2025

Kegiatan pengabdian ini didasari atas sebuah situasi di mana kemajuan teknologi digital telah memberikan dampak besar salah satunya dalam bidang pendidikan. Oleh karena itu, diperlukan suatu kegiatan pembelajaran dengan menggunakan QR Code sebagai media pembelajaran siswa. Dengan melibatkan QR Code dalam pembelajaran di sekolah dasar, maka siswa tidak hanya dibekali dengan ketrampilan literasi konvesional, tetapi juga membantu mereka mengembangakan literasi digital. Literasi digital menjadi kegiatan dalam mengoptimalkan teknologi informasi sekaligus menumbuhkan semangat literasi bagi siswa. Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan kemampuan literasi digital bagi siswa SDN 1 Tamanan Tulungagung. Metode pelaksanaan pengabdian ini menggunakan metode PAR (partipatoris action research) yang dilakukan dengan tiga tahap antara lain: perencanaan, pelaksanaan, dan evaluasi. Metode PAR melibatkan pelaksanakan kegiatan pengabdian untuk menjelaskan sebuah masalah maupun menerapkan informasi ke dalam aksi sebagai solusi atas masalah yang telah terdefinisi. Hasil akhir dari kegiatan pengabdian ini adalah siswa dapat memanfaatkan materi yang disediakan pada QR Code dan menghasilkan suatu karya majalah dinding. Materi yang disampaikan melalui QR Code adalah tentang pengenalan kebudayaan Indonesia. Siswa diminta untuk melakukan pemindaian QR Code, dan selanjutnya diarahkan ke link kumpulan materi yang berisi teks dan gambar untuk dibaca oleh siswa. Dilakukannya pemanfaatan QR Code dalam pembuatan majalah dinding dapat membantu siswa mengembangkan kemampuan sekaligus memberikan motivasi siswa agar memiliki kreativitas yang tinggi, memperluas pengetahuan dalam bidang komunikasi dan literasi visual, meningkatkan keterampilan kerja tim dan kemampuan dalam komunikasi. Harapan pada kegiatan pengabdian ini dapat meningkatkan kemampuan literasi digital siswa dan mendorong para siswa lebih aktif dalam mencari informasi melalui teknologi digital
Interpretación intercultural del derecho a la defensa como garantía del debido proceso en casos de justicia indígena en Ecuador
Authors: Patajalo Medina Milton Rolando , Flores Pérez Edgar Geovanny , Flores Tarambis José Luis , Arévalo Pacas Gabriela Katherine , Herrera Cevallos Jenny Marisol 
Published: January 2025

La investigación basa su análisis en el derecho establecido en la Constitución de la República, la que, en su artículo 1, reconoce al Ecuador como un “Estado constitucional de derechos y justicia, social, democrático, soberano, independiente, unitario, intercultural, plurinacional y laico.” (Const., Art. 1). En este contexto, el debido proceso es un pilar fundamental para que la justa, ordinaria y constitucional, resuelva conflictos o controversias; garantizando los derechos a la defensa de las personas afectadas, para que no queden en indefensión. En la interpretación intercultural, se examina los derechos reconocidos en la Constitución de la República del Ecuador y en los tratados y convenios internacionales, como el Convenio 169 de la Organización Internacional del Trabajo, en el cual se reconoce los derechos de los Pueblos Indígenas y Tribales, así como, entre otros, los lineamientos generales del debido proceso y el derecho a la defensa como un conjunto de garantías básicas que deben ser aplicadas en todos los procesos de justicia indígena que conozcan sus autoridades. Consecuentemente, la investigación realizada permite determinar que, respetar el derecho a la defensa en los procesos judiciales es importante, pero, resulta indispensable garantizar este derecho, como etapa del debido proceso, en los casos de justicia indígena. Más aún cuando, no existen parámetros de derecho a la defensa, estandarizados o previamente establecidos, en cada comunidad, sino que los resuelven basados en su derecho consuetudinario. A pesar de todo ello, es indispensable que se cumpla un debido proceso para evitar vulneración de derechos humanos en las personas juzgadas.
COMPARATIVE EFFECTS OF DIAPHRAGMATIC MYOFASCIAL RELEASE VERSUS DIAPHRAGMATIC BREATHING IN POST-OPERATIVE PATIENTS DIAGNOSED WITH GASTRO ESOPHAGEAL REFLUX DISEASE (GERD)
Authors: Tahir Hifza , Tahir Fizah , Iqbal Fatima , Tariq Faiza , Tahir Iqra , Dastgeer Ghulam , Asim Hafiz Ali Bin 
Published: January 2025

Background: GERD is a short form of “Gastro esophageal Reflux Disease”. It is a condition characterized by backflow of food particles from stomach to food pipe and associated symptoms.
Objective: To determine the comparative effects of Diaphragmatic breathing exercises and diaphragm atic myofascial release in post-operative patients diagnosed with GERD.
Methodology: We distributed participants through clinical trial. Postoperative patients diagnosed with GERD were studied. Sample size was 28. Patients were allocated to two treatment groups A and B by lottery method. Group A was treated with diaphragmatic myofascial release and Group B was treated with diaphragmatic breathing exercise. Reflux disease questionnaire (RDQ) was used as primary outcome measure for GERD. The secondary outcome measure was gastrointestinal symptom rating scale (GSRS)
Result: A cross group analysis revealed that there was statistical significant difference in post treatment values of GSRS and RDQ, with p values of 0.001and 0.001 respectively.
Conclusion: Diaphragmatic myofascial release is more effective than diaphragmatic breathing exercises in reducing the severity of GERD symptoms and improving quality of life in postoperative patients diagnosed with GERD.
Pendidikan Bagi Anak Berkebutuhan Khusus
Authors: Dahri Dahri , SH Hendra 
Published: January 2025

Pendidikan yang diterima oleh anak berkebutuhan khusus berbeda dengan pendidikan yang didapatkan oleh anak-anak normal lainnya. Pendidikan anak berkebutuhan khusus harus memperhatikan kecenderungan dan keterbatasan yang dimiliki. Melalui kajian literatur, penelitian ini menunjukkan bahwa anak berkebutuhan khusus membutuhkan pola pendidikan yang berbeda dari anak normal lainya. Selain treatment khusus, mereka juga perlu diberikan terapi untuk mengoptimalkan kelebihan dan meminimalkan keterbatasannya.
Do “desconforto” ao encontro comigo mesma
Authors: Almeida Luiza Nascimento 
Published: January 2025

The objective of this article is to provide an analysis of moments in the history of Ethnomusicology, during and following its inception, particularly when applied to Africa and the African diaspora. This analysis draws on authors from Brazil and abroad who have addressed this subject, specifically those who have situated it within the scope of ethno-racial relations – e.g., Kofi Agawu from Ghana, Mhoze Chikowero from Zimbabwe – thereby highlighting power relations with their asymmetries. Such asymmetries have resulted not only a mitigation of the epistemicide imposed by colonial/neocolonial whiteness on African-descended peoples but also the denial of Black peoples’ own protagonism in the context of their forms of expression, effectively silencing their personal narratives history. In this sense, the objective is to inquire which spaces are meant for the Black ethnomusicologist who finds him/herself confronted with the unease caused by the the biased tradition within this field of study.
Stages of formation of ideas about cognition (from the Ancient world to the New Time)
Authors: Rozin Vadim Markovich 
Published: December 2024

The article presents the author's reconstruction of the main stages of the origin of ideas about cognition. The picture of the reality of cognition accepted in modern science is presented, in which the yet unknown world is contrasted as a source of latent knowledge and patterns and a person as a cognizer striving to discover this knowledge. It is argued that in the Ancient World, such a familiar picture for a modern person did not take place. An analysis of the way of mastering the world related to this period shows that it represented the resolution of problematic situations through the invention of knowledge and schemes (local and fundamental), opening the way to understanding and new behavior. Together, local and fundamental schemes set the Ancient world, understandable and epistemologically transparent, requiring no knowledge. Man lived in a world of souls, spirits and gods. Although he created this world himself, solving problematic situations, he perceived it as having always existed. Cognition begins to take shape, starting with ancient culture; its prerequisites are the formation of an ancient personality and the invention of a new way of obtaining knowledge, not on diagrams, but in reasoning. The contribution of Plato and Aristotle to this revolutionary epistemic process is considered. The first introduces cognition as a dialectical and partly sacred way of understanding a new way of obtaining consistent knowledge. Stagirite transfers knowledge from heaven to earth, and places the source of new knowledge in things. Aristotle interprets this source as a hidden natural movement, calling it nature. The author reconstructs two more stages of the formation of knowledge related to the Middle Ages and modern times. It turned out that nature is not only movements hidden from human eyes, but those that are "written in the language of mathematics" and "constrained," as Francis Bacon wrote, by human art. The article ends with an indication of the next stage in the evolution of cognition, characteristic of the study of humanitarian and social phenomena.
The power of social identity in shaping collaborative success in research teams
Authors: Pedersen Malene Roland Vils 
Published: December 2024

Interdisciplinary research teams may from time to time face collaborative challenges due to many causes, e. g. various medical interests or professional background. Social identity theory offers a framework to understand these dynamics. Diverse interests or medical background can motivate and drive innovation and creativity in research projects but can also present challenges in term of communication and collaboration caused by different perspectives and traditions. This discussion paper focus on social theory related to team cohesion and collaboration, aiming to assist interdisciplinary teams in achieving collective and collaborative strengths.
Advances in Biomaterial‐Based Spinal Cord Injury Repair
Authors: Shen He , Fan Caixia , You Zhifeng , Xiao Zhifeng , Zhao Yannan , Dai Jianwu 
Published: December 2021

AbstractSpinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major challenge in neurological clinical practice. Understanding the pathophysiological changes and the inhibitory microenvironment is crucial to enable the identification of potential mechanisms for functional restoration and to provide guidance for the development of efficient treatment and repair strategies. To date, the implantation of specifically functionalized biomaterials in the lesion area has been shown to help promote axon regeneration and facilitate neuronal circuit generation by remolding SCI microenvironments. Moreover, structural and functional restoration of the spinal cord through the transplantation of naive spinal cord tissue grafts from adult donors, artificial spinal cord‐like tissue developed from tissue engineering, and 3D printing will open up new avenues for SCI treatment. This review focuses on the dynamic pathophysiological changes in SCI microenvironments, biomaterials for SCI repairs, strategies for restoring spinal cord structure and function, experimental animal models, regenerative mechanisms, and clinical studies for SCI repair. The current status, recent advances, challenges, and prospects of scaffold‐based SCI repair from basic to clinical settings are summarized and discussed, to provide a reference that will help to guide the future exploration and development of spinal cord regeneration strategies.
Creating a Ferromagnetic Ground State with Tc Above Room Temperature in a Paramagnetic Alloy through Non‐Equilibrium Nanostructuring
Authors: Ye Xinglong , Fortunato Nuno , Sarkar Abhishek , Geßwein Holger , Wang Di , Chen Xiang , Eggert Benedikt , Wende Heiko , Brand Richard A. , Zhang Hongbin , Hahn Horst , Kruk Robert 
Published: December 2021

AbstractMaterials with strong magnetostructural coupling have complex energy landscapes featuring multiple local ground states, thus making it possible to switch among distinct magnetic‐electronic properties. However, these energy minima are rarely accessible by a mere application of an external stimuli to the system in equilibrium state. A ferromagnetic ground state, with Tc above room temperature, can be created in an initially paramagnetic alloy by nonequilibrium nanostructuring. By a dealloying process, bulk chemically disordered FeRh alloys are transformed into a nanoporous structure with the topology of a few nanometer‐sized ligaments and nodes. Magnetometry and Mössbauer spectroscopy reveal the coexistence of two magnetic ground states, a conventional low‐temperature spin‐glass and a hitherto‐unknown robust ferromagnetic phase. The emergence of the ferromagnetic phase is validated by density functional theory calculations showing that local tetragonal distortion induced by surface stress favors ferromagnetic ordering. The study provides a means for reaching conventionally inaccessible magnetic states, resulting in a complete on/off ferromagnetic–paramagnetic switching over a broad temperature range.
Hierarchical Piezoresponse in Collagen
Authors: Cartwright Victoria F. , Brown Cameron P. 
Published: December 2021

AbstractThe piezoelectric nature of collagen has been known for decades, yet its manifestation across, and interactions between, hierarchies remains elusive. Here, piezoelectricity at the tropocollagen‐, microfibril‐, and fibril‐level hierarchies is examined experimentally, using collagen assembled from solution onto muscovite mica substrates. An amplification of the d15 response of 35–50% is observed between the tropocollagen and fibril levels, with no difference observed between the microfibril and fibril levels. Comparison of experimental results with simulation indicates the potential to optimize collagen piezoresponse via tropocollagen packing to exceed the piezoelectric properties of native collagen fibrils. By improving electromechanical performance through adjustments to winding angle and packing, it may therefore be possible to utilize collagen in low‐cost, biodegradable, and biocompatible sensing or harvesting devices.
Stereoselective Cyclopropanation of Boron Dipyrromethene (BODIPY) Derivatives by an Organocascade Reaction
Authors: Dočekal Vojtěch , Koberová Tereza , Hrabovský Jan , Vopálenská Andrea , Gyepes Róbert , Císařová Ivana , Rios Ramon , Veselý Jan 
Published: December 2021

AbstractThe synthesis of enantiopure chiral boron dipyrromethenes (BODIPYs) is of importance due the intrinsic properties of BODIPYs as fluorophores that could be used as probes for molecular sensing. The present study reports an asymmetric organocatalytic cascade reaction of meso‐chloromethyl BODIPY derivatives with α,β‐unsaturated aldehydes catalyzed by a chiral secondary amine. The corresponding BODIPY‐derived cyclopropanes were produced in isolated yields 66–98%, and with diastereomeric ratios 3/2–>20/1, and 92–99% ee for major diastereomer. The synthetic utility of the protocol was exemplified on a set of additional transformations of the corresponding optically pure compounds. In addition, a study explaining the reaction mechanism (DFT computations) and photophysical characterization of all enantioenriched products were accomplished.magnified image
Expanded phenotype of primary ciliary dyskinesia related to DRC1 pathogenic variant with dysmorphisms and vascular anomalies
Authors: LeBlanc Samuel , Allain Eric P. , Girouard Gabriel , Mallet Marcel , Amor Mouna Ben 
Published: December 2021

AbstractWe present a case of a female diagnosed with primary ciliary dyskinesia (PCD) type 21 with non‐previously reported extrapulmonary symptoms, including facial features and congenital vascular anomalies. Whole genome sequencing in our patient revealed a homozygous pathogenic variant in the DRC1 gene and no other notable structural nor punctual variants. This case demonstrates a unique clinical manifestation of PCD, which is possibly associated with the presence of a homozygous pathogenic DRC1 variant. Therefore, we suggest that analysis of DRC1 be considered with PCD type 21 when such features are present.
Trifluoroethanol as a Unique Additive for the Chemoselective Electrooxidation of Enamines to Access Unsymmetrically Substituted NH‐Pyrroles
Authors: Baidya Mrinmay , Maiti Debabrata , Roy Lisa , De Sarkar Suman 
Published: December 2021

AbstractAn electrochemical method for the synthesis of unsymmetrically substituted NH‐pyrroles is described. The synthetic strategy comprises a challenging heterocoupling between two structurally diverse enamines via sequential chemoselective oxidation, addition, and cyclization processes. A series of aryl‐ and alkyl‐substituted enamines were effectively cross‐coupled from an equimolar mixture to synthesize various unsymmetrical pyrrole derivatives up to 84 % yield. The desired cross‐coupling was achieved by tuning the oxidation potential of the enamines by utilizing a “magic effect” of the additive trifluoroethanol (TFE). Additionally, extensive computational studies reveal the unique role of TFE in promoting the heterocoupling process by regulating the activation energies of the reaction steps through H‐bonding and C−H⋅⋅⋅π interactions. Importantly, the developed electrochemical protocol was found to be equally efficient for the homocoupling of enamines to form symmetric pyrroles up to 92 % yield.
Fluorescence Imaging of Mitochondrial DNA Base Excision Repair Reveals Dynamics of Oxidative Stress Responses
Authors: Jun Yong Woong , Albarran Eddy , Wilson David L. , Ding Jun , Kool Eric T. 
Published: December 2021

AbstractMitochondrial function in cells declines with aging and with neurodegeneration, due in large part to accumulated mutations in mitochondrial DNA (mtDNA) that arise from deficient DNA repair. However, measuring this repair activity is challenging. We employ a molecular approach for visualizing mitochondrial base excision repair (BER) activity in situ by use of a fluorescent probe (UBER) that reacts rapidly with AP sites resulting from BER activity. Administering the probe to cultured cells revealed signals that were localized to mitochondria, enabling selective observation of mtDNA BER intermediates. The probe showed elevated DNA repair activity under oxidative stress, and responded to suppression of glycosylase activity. Furthermore, the probe illuminated the time lag between the initiation of oxidative stress and the initial step of BER. Absence of MTH1 in cells resulted in elevated demand for BER activity upon extended oxidative stress, while the absence of OGG1 activity limited glycosylation capacity.
Maximizing Step‐Normalized Increases in Molecular Complexity: Formal [4+2+2+2] Photoinduced Cyclization Cascade to Access Polyheterocycles Possessing Privileged Substructures
Authors: Reddy D. Sai , Novitskiy Ivan M. , Kutateladze Andrei G. 
Published: December 2021

AbstractA new complexity building photoinduced cascade which amounts to an unprecedented formal [4+2+2+2] cycloaddition topology is developed to access complex nitrogen polyheterocycles. This photocascade is initiated by the excited state intramolecular proton transfer (ESIPT) in aromatic amino ketones with tethered dual unsaturated pendants, i.e. pyrrole and alkenic moieties, resulting in the formation of four σ‐bonds and setting six new stereogenic centers in a single experimentally simple photochemical step with up to 220 mcbit complexity increases.
Structural Elucidation of Cryptic Algaecides in Marine Algal‐Bacterial Symbioses by NMR Spectroscopy and MicroED
Authors: Park Jong‐Duk , Li Yuchen , Moon Kyuho , Han Esther J. , Lee Seoung Rak , Seyedsayamdost Mohammad R. 
Published: December 2021

AbstractMicrobial secondary metabolite discovery is often conducted in pure monocultures. In a natural setting, however, where metabolites are constantly exchanged, biosynthetic precursors are likely provided by symbionts or hosts. In the current work, we report eight novel and architecturally unusual secondary metabolites synthesized by the bacterial symbiont Phaeobacter inhibens from precursors that, in a native context, would be provided by their algal hosts. Three of these were produced at low titres and their structures were determined de novo using the emerging microcrystal electron diffraction method. Some of the new metabolites exhibited potent algaecidal activity suggesting that the bacterial symbiont can convert algal precursors, tryptophan and sinapic acid, into complex cytotoxins. Our results have important implications for the parasitic phase of algal‐bacterial symbiotic interactions.
A Bright, Renal‐Clearable NIR‐II Brush Macromolecular Probe with Long Blood Circulation Time for Kidney Disease Bioimaging
Authors: Yao Chenzhi , Chen Ying , Zhao Mengyao , Wang Shangfeng , Wu Bin , Yang Yiwei , Yin Dongrui , Yu Peng , Zhang Hongxin , Zhang Fan 
Published: December 2021

AbstractEarly detection of kidney disease is of vital importance due to its current prevalence worldwide. Fluorescence imaging, especially in the second near‐infrared window (NIR‐II) has been regarded as a promising technique for the early diagnosis of kidney disease due to the superior resolution and sensitivity. However, the reported NIR‐II organic renal‐clearable probes are hampered by their low brightness (ϵmaxΦf>1000 nm<10 M−1 cm−1) and limited blood circulation time (t1/2<2 h), which impede the targeted imaging performance. Herein, we develop the aza‐boron‐dipyrromethene (aza‐BODIPY) brush macromolecular probes (Fudan BDIPY Probes (FBP 912)) with high brightness (ϵmaxΦf>1000 nm≈60 M−1 cm−1), which is about 10‐fold higher than that of previously reported NIR‐II renal‐clearable organic probes. FBP 912 exhibits an average diameter of ≈4 nm and high renal clearance efficiency (≈65 % excretion through the kidney within 12 h), showing superior performance for non‐invasively diagnosis of renal ischemia‐reperfusion injury (RIR) earlier than clinical serum‐based protocols. Additionally, the high molecular weight polymer brush enables FBP 912 with prolonged circulation time (t1/2≈6.1 h) and higher brightness than traditional PEGylated renal‐clearable control fluorophores (t1/2<2 h), facilitating for 4T1 tumor passive targeted imaging and renal cell carcinoma active targeted imaging with higher signal‐to‐noise ratio and extended retention time.