bluuebunny/crossref_metadata_2025_split huggingface dataset:
Photoisomerization of an Azobenzene‐Containing Surfactant Within a Micelle
Authors: Titov Evgenii , Sharma Anjali , Lomadze Nino , Saalfrank Peter , Santer Svetlana , Bekir Marek 
Published: July 2021

AbstractPhotosensitive azobenzene‐containing surfactants have attracted great attention in past years because they offer a means to control soft‐matter transformations with light. At concentrations higher than the critical micelle concentration (CMC), the surfactant molecules aggregate and form micelles, which leads to a slowdown of the photoinduced trans→cis azobenzene isomerization. Here, we combine nonadiabatic dynamics simulations for the surfactant molecules embedded in the micelles with absorption spectroscopy measurements of micellar solutions to uncover the reasons responsible for the reaction slowdown. Our simulations reveal a decrease of isomerization quantum yields for molecules inside the micelles. We also observe a reduction of extinction coefficients upon micellization. These findings explain the deceleration of the trans→cis switching in micelles of the azobenzene‐containing surfactants.
A hybrid discontinuous PWM algorithm of balancing neutral point voltage for 3L‐NPC inverter
Authors: Zhong Liping , Hu Song 
Published: July 2021

AbstractWider linear modulation range, less switching loss, and simplicity are the goals pursued by various modulation methods of multilevel inverters. This paper proposes a new hybrid discontinuous pulsewidth modulation (HDPWM) strategy for three‐level neutral‐point‐clamped (3L‐NPC) inverter that can achieve the above goals to a certain extent. According to the position of the reference voltage vector and the actual situation of the neutral point voltage, different control modes and clamping types are selected. The neutral point voltage is controlled by DPWM strategy, which can not only greatly reduce the switch loss but also maintain the balance of the neutral point voltage and expand the linear modulation range. The implementation of the algorithm combines the advantages of carrier‐based PWM (CBPWM) and space vector PWM (SVPWM). There is no need to select the nearest three vectors (NTVs) and calculate their dwell time. Only the reference voltage needs to be modified according to the control requirements, and then by comparing the modified reference voltage with the carrier, the driver pulse required by the switching devices can be generated. Compared with the existing PWM methods, it is more simple and easy to implement. Experimental results verify the validity of the method.
Evolutionary management of coral‐reef fisheries using phylogenies to predict density dependence
Authors: Houk Peter , Lemer Sarah , Hernandez‐Ortiz Dalia , Cuetos‐Bueno Javier 
Published: July 2021

AbstractHarvesting models are based upon the ideology that removing large, old individuals provides space for young, fast‐growing counterparts that can maximize (fisheries) yields while maintaining population stability and ecosystem function. Yet, this compensatory density dependent response has rarely been examined in multispecies systems. We combined extensive data sets from coral‐reef fisheries across a suite of Pacific islands and provided unique context to the universal assumptions of compensatory density dependence. We reported that size‐and‐age truncation only existed for 49% of target coral‐reef fishes exposed to growing fishing pressure across a suite of Pacific islands. In contrast, most of the remaining species slowly disappeared from landings and reefs with limited change to their size structure (i.e., little to no compensation), often becoming replaced by smaller‐bodied sister species. To understand these remarkable and disparate differences, we constructed phylogenies for dominant fish families and discovered that large patristic distances between sister species, or greater phylogenetic isolation, predicted size‐and‐age truncation. Isolated species appeared to have greater niche dominance or breadth, supported by their faster growth rates compared to species with similar sizes and within similar guilds, and many also have group foraging behavior. In contrast, closely related species may have more restricted, realized niches that led to their disappearance and replacement. We conclude that phylogenetic attributes offered novel guidance to proactively manage multispecies fisheries and improve our understanding of ecological niches and ecosystem stability.
Worldwide border interceptions provide a window into human‐mediated global insect movement
Authors: Turner Rebecca M. , Brockerhoff Eckehard G. , Bertelsmeier Cleo , Blake Rachael E. , Caton Barney , James Alex , MacLeod Alan , Nahrung Helen F. , Pawson Stephen M. , Plank Michael J. , Pureswaran Deepa S. , Seebens Hanno , Yamanaka Takehiko , Liebhold Andrew M. 
Published: July 2021

AbstractAs part of national biosecurity programs, cargo imports, passenger baggage, and international mail are inspected at ports of entry to verify compliance with phytosanitary regulations and to intercept potentially damaging nonnative species to prevent their introduction. Detection of organisms during inspections may also provide crucial information about the species composition and relative arrival rates in invasion pathways that can inform the implementation of other biosecurity practices such as quarantines and surveillance. In most regions, insects are the main taxonomic group encountered during inspections. We gathered insect interception data from nine world regions collected from 1995 to 2019 to compare the composition of species arriving at ports in these regions. Collectively, 8,716 insect species were intercepted in these regions over the last 25 yr, with the combined international data set comprising 1,899,573 interception events, of which 863,972 were identified to species level. Rarefaction analysis indicated that interceptions comprise only a small fraction of species present in invasion pathways. Despite differences in inspection methodologies, as well as differences in the composition of import source regions and imported commodities, we found strong positive correlations in species interception frequencies between regions, particularly within the Hemiptera and Thysanoptera. There were also significant differences in species frequencies among insects intercepted in different regions. Nevertheless, integrating interception data among multiple regions would be valuable for estimating invasion risks for insect species with high likelihoods of introduction as well as for identifying rare but potentially damaging species.
Analytical methods matter too: Establishing a framework for estimating maximum metabolic rate for fishes
Authors: Prinzing Tanya S. , Zhang Yangfan , Wegner Nicholas C. , Dulvy Nicholas K. 
Published: July 2021

AbstractAdvances in experimental design and equipment have simplified the collection of maximum metabolic rate (MMR) data for a more diverse array of water‐breathing animals. However, little attention has been given to the consequences of analytical choices in the estimation of MMR. Using different analytical methods can reduce the comparability of MMR estimates across species and studies and has consequences for the burgeoning number of macroecological meta‐analyses using metabolic rate data. Two key analytical choices that require standardization are the time interval, or regression window width, over which MMR is estimated, and the method used to locate that regression window within the raw oxygen depletion trace. Here, we consider the effect of both choices by estimating MMR for two shark and two salmonid species of different activity levels using multiple regression window widths and three analytical methods: rolling regression, sequential regression, and segmented regression. Shorter regression windows yielded higher metabolic rate estimates, with a risk that the shortest windows (<1‐min) reflect more system noise than MMR signal. Rolling regression was the best candidate model and produced the highest MMR estimates. Sequential regression models consistently produced lower relative estimates than rolling regression models, while the segmented regression model was unable to produce consistent MMR estimates across individuals. The time‐point of the MMR regression window along the oxygen consumption trace varied considerably across individuals but not across models. We show that choice of analytical method, in addition to more widely understood experimental choices, profoundly affect the resultant estimates of MMR. We recommend that researchers (1) employ a rolling regression model with a reliable regression window tailored to their experimental system and (2) explicitly report their analytical methods, including publishing raw data and code.
Risk factors for diabetic foot complications among patients with type 2 diabetes in Austria–A registry‐based retrospective cohort study
Authors: Rossboth Sophia , Rossboth Benedikt , Schoenherr Hans , Lechleitner Monika , Oberaigner Willi 
Published: July 2021

AbstractAimsDiabetic foot complications, a serious consequence of diabetes mellitus, are associated with a tremendous burden on both individual patients and health care systems. Since prevention strategies may reduce the incidence of this complication, identification of risk factors in large longitudinal studies is essential to optimize early detection and personalized screening of patients at increased risk.Materials and methodsWe conducted a registry‐based retrospective cohort study using data from 10,688 patients with type 2 diabetes mellitus aged ≥18 years. Cox regression models were used to identify risk factors for foot complications while adjusting for potential confounders.ResultsWe observed 140 diabetic foot complications in our patient cohort. The multivariate Cox regression model revealed neuropathy, peripheral arterial disease and male gender as being positively associated with foot complications. The same effect was detected for nephropathy in the time >10 years after T2DM diagnosis. For higher age at diagnosis and use of insulin, however, a negative association was retrieved.ConclusionMale gender and several diabetes‐related comorbidities were identified as risk factors for subsequent initial foot complications in patients with type 2 diabetes mellitus. These findings suggest that personalized early detection of patients at increased risk might be feasible by using information on demographics, medical history and comorbidities.
Molecular dietary analyses of western capercaillies (Tetrao urogallus) reveal a diverse diet
Authors: Chua Physilia Ying Shi , Lammers Youri , Menoni Emmanuel , Ekrem Torbjørn , Bohmann Kristine , Boessenkool Sanne , Alsos Inger Greve 
Published: July 2021

AbstractConservation strategies centered around species habitat protection rely on species’ dietary information. One species at the focal point of conservation efforts is the herbivorous grouse, the western capercaillie (Tetrao urogallus), which is an indicator species for forest biodiversity conservation. Non‐molecular means used to study their diet are time‐consuming and at low taxonomic resolution. This delays the implementation of conservation strategies including resource protection due to uncertainty about its diet. Thus, limited knowledge on diet is hampering conservation efforts. Here, we use non‐invasive environmental DNA (eDNA) metabarcoding on DNA extracted from faces to present the first large‐scale molecular dietary analysis of capercaillies. Facal samples were collected from seven populations located in Norway (Finnmark, Troms, Trøndelag, Innlandet) and France (Vosges, Jura, Pyrenees) (n = 172). We detected 122 plant taxa belonging to 46 plant families of which 37.7% of the detected taxa could be identified at species level. The average dietary richness of each sample was 7 ± 5 SD taxa. The most frequently occurring plant groups with the highest relative read abundance (RRA) were trees and dwarf shrubs, in particular, Pinus and Vaccinium myrtillus, respectively. There was a difference in dietary composition (RRA) between samples collected from the different locations (adonis pseudo F5,86 = 11.01, r2 = 0.17, p = 0.001) and seasons (adonis pseudo F2,03 = 0.64, r2 = 0.01, p = 0.036). Dietary composition also differed between sexes at each location (adonis pseudo F1,47 = 2.77, r2 = 0.04, p = 0.024), although not significant for all data combined. In total, 35 taxa (36.8% of taxa recorded) were new capercaillie food items compared with existing knowledge from non‐molecular means. The non‐invasive molecular dietary analysis applied in this study provides new ecological information of capercaillies’ diet, improving our understanding of adequate habitat required for their conservation.
Disposable Electrochemical Aptasensor for Ultrasensitive Determination of Aflatoxin B1 Using Copper Nanoparticles as Probes
Authors: Liu Jiaxiang , Zhou Yanli , Dong Hui , Li Qiaoxia , Zhang Yintang , Xu Maotian 
Published: July 2021

AbstractAn electrochemical aptasensor for aflatoxin B1 (AFB1) detection was constructed based on the copper nanoparticles (CuNPs) and gold nanoflowers modified screen‐printed carbon electrodes as electrochemical probes and substrates, respectively. In the range of 100 aM to 100 pM, a good linear relationship between oxidation peak current of CuNPs and concentration of AFB1 was obtained. The high sensitivity could be ascribed to the amplified electrochemical signals by CuNPs. The high affinity of AFB1 with aptamer endowed its high selectivity. The above advantages and disposable traits made this aptasensor as an ideal platform for evaluation of AFB1 level in food samples.
Macroscopically Oriented Magnetic Core‐regularized Nanomaterials for Glucose Biosensors Assisted by Self‐sacrificial Label
Authors: Yin Shiyu , Wang Jikui , Li Yan , Wu Tingxia , Song Lingyu , Zhu Yongbao , Chen Yizhe , Cheng Kai , Zhang Jun , Ma Xinzhou , Donghai Lin , Chen Guosong 
Published: July 2021

AbstractMagnetic core‐regular nanostructures composed of magnetite and regular Prussian blue was prepared by self‐sacrificial macro‐oriented method. Magnetic graphene oxide (MGO) was vertically oriented on the surface of home‐made screen‐printing electrode with the help of constant magnetic field (CMF).Then regular nanostructured Prussian blue (RPB) was realized by chemical reaction through an aerosol deposition. Finally, glucose oxidase (GOx) was immobilized by glutaraldehyde cross‐linking to fabricate glucose biosensors. The linear range of CMF‐RPB/MGO sensor towards glucose was 0.03∼1.35 mM, and the detection limit was 13.4 μM. The CMF‐RPB/MGO sensor could apply to analyze glucose in human serum samples.
The anti‐inflammatory and antiapoptotic effects of probiotic on induced neurotoxicity in juvenile hamsters
Authors: Ben Bacha Abir , Al‐Orf Norah , Alonazi Mona , Bhat Ramesa Shafi , El‐Ansary Afaf 
Published: July 2021

AbstractBrain inflammation and apoptosis play crucial roles in the pathogenesis of various neurodevelopmental disorders. Probiotics have been shown to confer protection against many stresses, including apoptosis and inflammation, by modulating the gut function. The short‐chain fatty acid, propionic acid (PPA), plays an important intermediate of cellular metabolism. Although PPA exhibits numerous beneficial biological effects, its accumulation is neurotoxic. This study focused on the therapeutic potency of probiotics against PPA‐induced apoptosis and neuroinflammation in hamsters. Five groups of male golden Syrian hamsters were treated as follows: Group I as control; Group II as PPA‐treated with three doses of 250 mg PPA/kg/day; Group III as clindamycin‐treated with a single dose of 30 mg clindamycin/kg; Group IV as PPA–probiotic; and Group V as clindamycin–probiotic were two therapeutic groups which were treated with the same doses of PPA and clindamycin, respectively, followed by treatment with 0.2 g kg‐1 d−1 of probiotic (ProtexinR, Probiotics International Limited) for three weeks. Proapoptotic markers, such as caspases 3 and 7; neuroinflammation markers, such as interleukins 1β and 8; and heat shock protein 70 were measured in the brain. Significant increase of all measured markers (p ˂ .001) was observed in PPA and clindamycin‐treated hamsters compared with controls. Probiotics significantly reduced the damages and ameliorated all the test markers in both therapeutic groups compared with the control. Our results confirmed that probiotics can be utilized as a feasible strategy for managing apoptotic and inflammation‐related stresses in brain disorders by retaining the gut function.
Petrogenesis of the Pandao granites in the Wutai Mountains area in the North China Craton: Constraints from geochemistry, zircon U–Pb geochronology, and Hf isotopes
Authors: Ye Feng , Dong Guochen , Ren Jianxun , Ketchaya Yanick Blaise , Yang Quanlin , Niu Xiaoyang , Dang Hongmin , Bai Yubo , Dong Chen , Li Baifu 
Published: July 2021

The Trans‐North China Orogen (TNCO) is a part of the North China Craton (NCC) and together provides a classic example of lithospheric destruction. The Pandao granites outcropping in the Wutai Mountains area provide a window to investigate the Mesozoic magmatism in the TNCO. Here, this paper presents the new zircon geochronology, whole‐rock geochemistry, and zircon Hf isotope data for the Pandao granites to discuss their petrogenesis and tectonic implications. The Pandao granites are mainly composed of light‐red medium‐ to coarse‐grained biotite granite and light‐grey fine‐ to medium‐grained biotite granite. Zircon U–Pb ages of 110.05 ± 0.67 Ma and 108.35 ± 0.81 Ma suggest that the Pandao granites were crystallized in the Early Cretaceous. The Pandao granites are classified as high‐K calc‐alkaline and weak peraluminous series. The rocks display abundance in large‐ion lithophile elements (LILE) and light rare‐earth elements (LREE) but show depletion in high‐field‐strength elements (HFSE) and heavy rare‐earth elements (HREE), with strong negative Eu anomalies. The classification diagrams indicate that the Pandao granites are A‐type granites and thus belong to the A1 subtype, formed in an intraplate extensional environment. The Pandao granites have homogeneous zircon Hf isotopic compositions. Their zircons have negative εHf(t) values (−19.1 to −17.1) and old Hf isotope crustal model ages (2,250–2,375 Ma), suggesting that the Pandao granites were formed by partial melting of the Paleoproterozoic lower crustal material. Therefore, it is suggested that the Pandao granites were formed under an intraplate extensional tectonic environment of remote effect due to the ancient Pacific Plate subduction and retreat beneath the Eurasian continent. The TNCO was influenced by the subduction and retreat of the ancient Pacific Plate in the late Early Cretaceous.
Equal Access to Organ Transplantation for People with Disabilities
Authors: Pendo Elizabeth 
Published: July 2021

AbstractPeople with disabilities are often denied equal access to organ transplantation despite long‐standing federal nondiscrimination mandates. Under the Americans with Disabilities Act and the Rehabilitation Act, people cannot be excluded from consideration for organ transplantation because of disability itself, or because of stereotypes or assumptions about the value or quality of life with a disability. Instead, decisions concerning whether an individual is a candidate for organ transplantation should be based on an individualized assessment of the patient and on objective medical evidence. Recent legal developments underscore these basic guarantees and signal a new focus on the policies, practices, and attitudes that continue to compromise equal access to life‐saving organ transplants for people with disabilities.
Care Ethics versus the CARES Act
Authors: Sontan Oluwatomisin 
Published: July 2021

AbstractOne of the biggest policy interventions during the last year of the COVID‐19 pandemic was the Coronavirus Aid, Relief, and Economic Securities Act, instituting a novel form of economic relief similar to a universal basic income. The economic impact payments, colloquially known as “stimulus checks,” were distributed based on the socioeconomic status of American citizens and legal residents and provided much‐needed financial aid. However, the distribution of these payments paid little attention to other important factors that might determine the economic security of said individuals, such as race and gender. This article calls for policy‐makers to pay particular attention to how structural inequity and discrimination based on identity could affect the efficacy of proposed policies and demonstrate an ethic of care informed by an understanding of intersectionality.
Activism and the Clinical Ethicist
Authors: Meyers Christopher 
Published: July 2021

AbstractAlthough clinical ethics scholarship and practice has largely avoided assuming an activist stance, the many health care crises of the last eighteen months motivated a distinct change: On listserves, in blog postings, and in published essays, activist language has permeated conversations over such issues as the impact of triage policies on persons with disabilities and of color, and how the health care system has historically failed African Americans.In this paper, I defend this turn, arguing that clinical ethicists should embrace activism—generally, and with particular emphasis on institutional, mesolevel concerns. Ethicists are often uniquely situated to understand the structural factors that regularly motivate clinical ethics cases, and they are often in a privileged position to be effective change agents. In making this case, I also stress the need not to overstep one's skills and to be acutely cognizant of the political risks associated with such work.
Antiracist Activism in Clinical Ethics: What's Stopping Us?
Authors: Vo Holly , Campelia Georgina D. 
Published: July 2021

AbstractAlthough justice is a central principle in clinical ethics, work that centers social justice is often marginalized in clinical ethics. In addition to institutional barriers that may be preventing clinical ethicists from becoming the activists that Meyers argues we should be, we must also recognize the barriers embedded in the field of clinical ethics itself. As clinical ethicists, we have an opportunity to support anti‐racism work in particular by altering our own organizational structures to be more inclusive and reflective of the Black, Indigenous, and other communities of color we serve, enhancing clinical ethics education and training by making critical theories foundational, and decolonizing our clinical ethics consultation tools and practices.
Why Clinical Ethicists Are Not Activists
Authors: Elliott Carl 
Published: July 2021

AbstractActivism is rare among clinical ethicists because the position of ethics consultant is constructed in a way that makes activism very difficult. Clinical ethicists have little formal power and few job protections; they work in organizations in which dissent is discouraged if not punished; and as institutional insiders, they often become blind to the injustices that outsiders protest against.