bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extremal bifurcations of rotating AdS4 black holes
Authors: McInnes Brett 
Published: December 2021

Abstract
The Weak Gravity Conjecture arises from the assertion that all extremal black holes, even those which are “classical” in the sense of being very massive, must decay by quantum-mechanical emission of particles or smaller black holes. This is interesting, because some observed astrophysical black holes are on the brink of being extremal — though this is due to rapid rotation rather than a large electric or magnetic charge. The possibility that rotating near-extremal black holes might, in addition to radiating spinning particles, also bifurcate by emitting smaller black holes, has attracted much attention of late. There is, however, a basic question to be answered here: can such a bifurcation be compatible with the second law of thermodynamics? This is by no means clear. Here we show that, if there is indeed such a mechanism for bifurcations of AdS4-Kerr-Newman black holes, then this process can in fact satisfy the second law.
Derived representation schemes and Nakajima quiver varieties
Authors: D’Alesio Stefano 
Published: December 2021

AbstractWe introduce a derived representation scheme associated with a quiver, which may be thought of as a derived version of a Nakajima variety. We exhibit an explicit model for the derived representation scheme as a Koszul complex and by doing so we show that it has vanishing higher homology if and only if the moment map defining the corresponding Nakajima variety is flat. In this case we prove a comparison theorem relating isotypical components of the representation scheme to equivariant K-theoretic classes of tautological bundles on the Nakajima variety. As a corollary of this result we obtain some integral formulas present in the mathematical and physical literature since a few years, such as the formula for Nekrasov partition function for the moduli space of framed instantons on$$S^4$$S4. On the technical side we extend the theory of relative derived representation schemes by introducing derived partial character schemes associated with reductive subgroups of the general linear group and constructing an equivariant version of the derived representation functor for algebras with a rational action of an algebraic torus.
Safety and Effectiveness of the New Generation APERIO® Hybrid Stent-retriever Device in Large Vessel Occlusion Stroke
Authors: Vogt Marius L. , Kollikowski Alexander M. , Weidner Franziska , Strinitz Marc , Feick Jörn , Essig Fabian , Neugebauer Hermann , Haeusler Karl Georg , Pham Mirko , Maerz Alexander 
Published: December 2021

Abstract
Background
It is unknown whether technological advancement of stent-retriever devices influences typical observational indicators of safety or effectiveness.

Methods
Observational retrospective study of APERIO® (AP) vs. new generation APERIO® Hybrid (APH) (Acandis®, Pforzheim, Germany) stent-retriever device (01/2019–09/2020) for mechanical thrombectomy (MT) in large vessel occlusion (LVO) stroke. Primary effectiveness endpoint was successful recanalization eTICI (expanded Thrombolysis In Cerebral Ischemia) ≥ 2b67, primary safety endpoint was occurrence of hemorrhagic complications after MT. Secondary outcome measures were time from groin puncture to first pass and successful reperfusion, and the total number of passes needed to achieve the final recanalization result.

Results
A total of 298 patients with LVO stroke who were treated by MT matched the inclusion criteria: 148 patients (49.7%) treated with AP vs. 150 patients (50.3%) treated with new generation APH. Successful recanalization was not statistically different between both groups: 75.7% for AP vs. 79.3% for APH; p = 0.450. Postinterventional hemorrhagic complications and particularly subarachnoid hemorrhage as the entity possibly associated with stent-retriever device type was significantly less frequent in the group treated with the APH: 29.7% for AP and 16.0% for APH; p = 0.005; however, rates of symptomatic hemorrhage with clinical deterioration and in domo mortality were not statistically different. Neither the median number of stent-retriever passages needed to achieve final recanalization, time from groin puncture to first pass, time from groin puncture to final recanalization nor the number of cases in which successful recanalization could only be achieved by using a different stent-retriever as bail-out device differed between both groups.

Conclusion
In the specific example of the APERIO® stent-retriever device, we observed that further technological developments of the new generation device were not associated with disadvantages with respect to typical observational indicators of safety or effectiveness.
Validation of the Thai version of the Prolapse and Incontinence Knowledge Questionnaire (PIKQ)
Authors: Komon Wanchat , Manonai Jittima , Kijmanawat Athasit , Silpakit Chatchawan , Tunkoon Bhatarachit , Jengprasert Ketkaew , Sarit-apirak Sirirat 
Published: December 2021

Abstract
Introduction and hypothesis
The Prolapse and Incontinence Knowledge Questionnaire (PIKQ) was developed and validated to assess women’s knowledge regarding etiology, diagnosis and treatment of pelvic organ prolapse (POP) and urinary incontinence (UI). We aimed to translate and validate a Thai version of the PIKQ to use as a tool to evaluate knowledge of POP and UI among Thai-speaking women.

Methods
The English PIKQ, which comprises the PIKQ-POP and PIKQ-UI sections, was translated into Thai. Psychometric properties of the final version of the Thai PIKQ were tested for content validity, construct validity, internal consistency and test-retest reliability among 168 women attending a gynecology clinic and 150 nurses.

Results
Regarding content validity of the final Thai PIKQ, the number of missing items was 0. Participants in the nurse group were more likely than those in the patient group to select the correct answer for all items for the POP scale and UI scale (P < 0.001). For internal consistency testing, Cronbach’s alpha coefficient was 0.745 for the PIKQ-POP and 0.754 for the PIKQ-UI scales, suggesting that the items had relatively high internal consistency. The item-total correlation values ranged from 0.204 to 0.539, showing an adequate correlation of each item with the scale overall. The correlation coefficients between the test and retest for PIKQ-POP and PIKQ-UI were 0.685 and 0.735, respectively (P < 0.001).

Conclusions
The Thai PIKQ is a simple instrument which shows good validity and high reliability and could be a useful tool for assessing knowledge regarding POP and UI in clinical practice.
Antenatal pelvic floor muscle training and urinary incontinence: a randomized controlled 7-year follow-up study
Authors: Stafne Signe Nilssen , Dalbye Rebecka , Kristiansen Oda M. , Hjelle Yvonne E. , Salvesen Kjell Åsmund , Mørkved Siv , Johannessen Hege Hølmo 
Published: December 2021

Abstract
Introduction and hypothesis
Urinary incontinence is common postpartum. Our aims were to assess whether antenatal exercise including pelvic floor muscle training (PFMT) has long-term effects on urinary incontinence (UI) and to explore factors associated with UI 7 years postpartum.

Methods
A follow-up of a two-centre randomized controlled trial performed at St. Olavs Hospital and Stavanger University Hospital, Norway. In the original trial women were randomized to a 12-week structured exercise protocol including PFMT or standard antenatal care during pregnancy. Link to an electronic questionnaire was sent by postal mail 7 years postpartum. Prevalence of UI was assessed with Sandvik severity index and compared between groups. Factors associated with UI were studied using multivariable logistic regression analysis.

Results
The response rate was 35% (298/855). UI was reported by 78 (51%) in the intervention group and 63 (57%) in the control group (p = 0.539). In the multivariable logistic regression analyses, women with UI at inclusion had a five-fold increase in odds of UI at 7 years (OR 5.4, 95% CI 2.6, 11.5). Engaging in regular exercise was not significantly associated with UI at 7 years; however, UI was associated with lower exercise intensity (OR 2.4, 95% CI 1.2, 4.6).

Conclusions
We found no group differences of antenatal exercise including PFMT on UI after 7 years among the responders. UI in pregnancy increased the risk of long-term UI. Regular exercise was not associated with UI at 7 years; however, women with UI were more than twice as likely to exercise at lower intensity than continent women.
Prevalence, contributory factors and severity of medication errors associated with direct-acting oral anticoagulants in adult patients: a systematic review and meta-analysis
Authors: Al Rowily Abdulrhman , Jalal Zahraa , Price Malcolm J. , Abutaleb Mohammed H. , Almodiaemgh Hind , Al Ammari Maha , Paudyal Vibhu 
Published: December 2021

Abstract
Purpose
This study aimed to estimate the prevalence, contributory factors, and severity of medication errors associated with direct acting oral anticoagulants (DOACs).

Methods
A systematic review and meta-analysis were undertaken by searching 11 databases including Medline, Embase, and CINHAL between January 2008 and September 2020. The pooled prevalence of errors and predictive intervals were estimated using random-effects models using Stata software. Data related to error causation were synthesised according to Reason’s accident causation model.

Results
From the 5205 titles screened, 32 studies were included which were mostly based in hospitals and included DOAC treatment for thromboembolism and atrial fibrillation. The proportion of study population who experienced either prescription, administration, or dispensing error ranged from 5.3 to 37.3%. The pooled percentage of patients experiencing prescribing error was 20% (95% CI 15–25%; I2 = 96%; 95% PrI 4–43%). Prescribing error constituted the majority of all error types with a pooled estimate of 78% (95%CI 73–82%; I2 = 0) of all errors. The common reported causes were active failures including wrong drug, and dose for the indication. Mistakes such as non-consideration of renal function, and error-provoking conditions such as lack of knowledge were common contributing factors. Adverse events such as potentially fatal intracranial haemorrhage or patient deaths were linked to the errors but causality assessments were often missing.

Conclusions
Despite their favourable safety profile, DOAC medication errors are common. There is a need to promote multidisciplinary working, guideline-adherence, training, and education of healthcare professionals, and the use of theory-based and technology-facilitated interventions to minimise errors and maximise the benefits of DOACs usage in all settings.

Protocol
A protocol developed as per PRISMA-P guideline is registered under PROSPERO ID = CRD42019122996
Application of reinforcement learning for the optimization of clinch joint characteristics
Authors: Zirngibl Christoph , Dworschak Fabian , Schleich Benjamin , Wartzack Sandro 
Published: December 2021

AbstractDue to increasing challenges in the area of lightweight design, the demand for time- and cost-effective joining technologies is steadily rising. For this, cold-forming processes provide a fast and environmentally friendly alternative to common joining methods, such as welding. However, to ensure a sufficient applicability in combination with a high reliability of the joint connection, not only the selection of a best-fitting process, but also the suitable dimensioning of the individual joint is crucial. Therefore, few studies already investigated the systematic analysis of clinched joints usually focusing on the optimization of particular tool geometries against shear and tensile loading. This mainly involved the application of a meta-model assisted genetic algorithm to define a solution space including Pareto optima with all efficient allocations. However, if the investigation of new process configurations (e. g. changing materials) is necessary, the earlier generated meta-models often reach their limits which can lead to a significantly loss of estimation quality. Thus, it is mainly required to repeat the time-consuming and resource-intensive data sampling process in combination with the following identification of best-fitting meta-modeling algorithms. As a solution to this problem, the combination of Deep and Reinforcement Learning provides high potentials for the determination of optimal solutions without taking labeled input data into consideration. Therefore, the training of an Agent aims not only to predict quality-relevant joint characteristics, but also at learning a policy of how to obtain them. As a result, the parameters of the deep neural networks are adapted to represent the effects of varying tool configurations on the target variables. This provides the definition of a novel approach to analyze and optimize clinch joint characteristics for certain use-case scenarios.
The CUSUM statistic of change point under NA sequences
Authors: Ling Jin , Li Xiao-qin , Yang Wen-zhi , Jiao Jian-ling 
Published: December 2021

AbstractIn this paper, we investigate the CUSUM statistic of change point under the negatively associated (NA) sequences. By establishing the consistency estimators for mean and covariance functions respectively, the limit distribution of the CUSUM statistic is proved to be a standard Brownian bridge, which extends the results obtained under the case of an independent normal sample and the moving average processes. Finally, the finite sample properties of the CUSUM statistic are given to show the efficiency of the method by simulation studies and an application on a real data analysis.
Fuzzy Zorn’s lemma with applications
Authors: Xin Xiao-long , Fu Yu-long 
Published: December 2021

AbstractWe introduced the fuzzy axioms of choice, fuzzy Zorn’s lemma and fuzzy well-ordering principle, which are the fuzzy versions of the axioms of choice, Zorn’s lemma and well-ordering principle, and discussed the relations among them. As an application of fuzzy Zorn’s lemma, we got the following results: (1) Every proper fuzzy ideal of a ring was contained in a maximal fuzzy ideal. (2) Every nonzero ring contained a fuzzy maximal ideal. (3) Introduced the notion of fuzzy nilpotent elements in a ring R, and proved that the intersection of all fuzzy prime ideals in a commutative ring R is the union of all fuzzy nilpotent elements in R. (4) Proposed the fuzzy version of Tychonoff Theorem and by use of fuzzy Zorn’s lemma, we proved the fuzzy Tychonoff Theorem.
Assessment of the Antimicrobial and Fertilizing Activity of Table Olive Concentrated Waste Streams During Their Shelf Life
Authors: Brenes Manuel , De Los Santos Berta , Aguado Ana , De Castro Antonio , García Pedro , Romero Concepción 
Published: December 2021

AbstractTable olive wastewaters represent a big problem for factories not yet solved. Some partial solutions are the purification, the reuse or the generation of a smaller volume of these liquids. The purpose of this study was to investigate the possibility of obtaining a concentrate that can be stable over time and that has a biofertilizing capacity on tomato (Solanum lycopersicum L.) plants. In this study, washing waters from Spanish style green and storage liquids from black ripe olive processing were vacuum concentrated up to 10, 13 and 17 times so that they reached total sugar content of up to 700 mmol L−1, 925 mmol L−1 and 1200 mmol L−1 respectively. Interestingly, the evaporation achieved to retain most of the phenolic compounds that ranged from 18 mmol L−1 in the fresh solution to 140 mmol L−1 in the solution concentrated 10 times. Moreover, these concentrates showed in vitro antimicrobial activity against the bacteria Erwinia amylovora and Pseudomonas syringae, and the Oomycota Phytophthora sp. In addition, they increased the strength and cumulative yield of the tomato plants cultivated under greenhouse conditions, even after 12 months of storage at room temperature. It has been demonstrated that it is possible to reduce the large volume of the wastewaters of the table olive industry, and the concentrates have potential application for agricultural uses, even after 1 year of storage, thereby contributing to a more environmentally sustainable industry.
Graphical Abstract
Stratigraphic architecture and depositional environment of the Paleocene-Lower Eocene aquifers system (Douala onshore basin, SW Cameroon)
Authors: Koah Na Lebogo Serge Parfait , Bisso Dieudonnée , Ngo Elogan Ntem Jeannette , Mvondo Ondoa Joseph 
Published: December 2021

AbstractThe Paleocene-Lower Eocene N'kapa Formation has long been considered as an important groundwater and hydrocarbon resource in the eastern edge of the Douala Basin. The present study’s aim is to establish a possible link between the geological nature of this formation and the quality of potential aquifers using Gamma Ray well log, cuttings and outcrops through sedimentology and sequence stratigraphy studies. The results obtained from this study show that: lithofacies are dominated by clays, silts and sands/sandstones; gamma ray electrofacies are funnel-shaped to cylindrical-shaped with some bell-shaped; depositional environments are continental to shallow marine dominated by fluvial and sometimes tidal processes; fluvial channel-fill, tidal channel-fill and delta front bars sands are potential aquifers; sequence stratigraphy analysis reveals two transgressive–regressive cycles of second order (Danian to Selandian and Thanetian to Ypresian), two Highstand System Tracts, one Transgressive System Tract and one Lowstand System Tract; the high-resolution geometry of these sandy/sandstone sedimentary bodies shows that their distribution is linked to the hydrodynamic factors and the topography of the depositional environment. A total of two types of lithological facies of the reservoir levels were defined according to the volume of clay: clean sandstone (0–15%) and low clayey sandstone (15–30%). The gamma ray well log correlation shows that the thickness of the reservoir levels is variable and that the clay content (Vsh%) increases from the NE to the SW. As a result, the best potential aquifers appear to correspond to the fluvial channel-fill sands deposited during the base-level fall of Upper Paleocene age (Lower Thanetian).
Utilization of produced condensate for enhanced oil recovery: a case study for the forest reserve field in Trinidad
Authors: Lall Daron , Alexander David , Maharaj Rean , Narace Indar , Soroush Mohammad 
Published: December 2021

AbstractThe current global economic trends of low commodity prices for hydrocarbons, competition due to the emergence of shale oil and gas, as well as the decline in production from mature oilfields in Trinidad and Tobago (TT) have fuelled the need for the implementation of efficient and enhanced oil recovery methods. Of particular concern locally is the issue of decreasing oil production and increasing production costs in mature oil fields due to the prevalence of organic deposits (paraffin or asphaltenes), which results in the coating of production tubing causing the plugging of surface equipment, pipelines, perforations and pore spaces in the geological formation. Major deposition compound paraffins and asphaltene are soluble in condensate, which is relatively cheap and is produced as a by-product and flared in TT, and it is already used as a pipeline diluent and cleaner for deposits. The strategy of utilizing this “waste” solvent as an economical and environmentally friendly strategy for EOR was worth investigation. The FR 1346 RD well was selected for evaluation, and a pilot test was conducted using the compositional reservoir simulation model (CMG–GEM). Laboratory studies were conducted using a constructed pressure permeability flow chamber, and results from the device indicated that an asphaltene plug decreased the permeability by approximately 24%, but after treatment with condensate, there was an improvement in permeability of approximately 10% (300 md to 420 md). Tuning of the simulation model incorporating the laboratory-derived permeability data resulted in an increase in production rate to 35 bopd, which matched very closely with the field pilot well test result of an increase of 46% (from 20 to 39 bopd) when the condensate soak was performed. This increase translated in an overall gain of 30,531 bbls of oil associated with a financial gain of approximately $4.7 MM TT per well over the 16-year period. Injection types including condensate, carbon dioxide and nitrogen yielded the production of the same order. This study offers compelling evidence that the use of produced condensate in EOR is an economically and environmentally friendly strategy in TT.
Improvement of a multiphase flow model for wellhead chokes under critical and subcritical conditions using field data
Authors: Leporini Mariella , Terenzi Alessandro , Marchetti Barbara 
Published: December 2021

AbstractThe characterization of the multiphase flow through valves and orifices is a problem yet to be solved in engineering design, and there is a need for a prediction model able to simulate the complexity of this kind of flow in relation to fluid thermodynamic behaviour, and applicable to different incoming stream conditions and compositions. The present paper describes the development of a global model for the calculation of the discharge coefficient of orifices and choke valves operating under two- and three-phase flow as well as critical and subcritical conditions. The model generalizes the hydrovalve model developed by Selmer-Olsen et al. (in: Wilson (ed) Proceedings of 7th international conference on Multiphase Production, BHR Group, pp 441–446, 1995) and the Henry–Fauske (J Heat Transfer 93: 179–187, 1971. 10.1115/1.3449782) non-equilibrium model on the basis of an updated definition of the discharge coefficient. The model has been adapted to real choke valve geometries, by fitting the discharge coefficient and model parameters using field data from three production wells. The model developed is a global quartic function with different constants for the different valve geometries. The new discharge coefficient allows to simulate field data with high accuracy.