bluuebunny/crossref_metadata_2025_split huggingface dataset:
Duodenum-preserving pancreatic head resections for surgical treatment of paraduodenal pancreatitis
Authors: Usenko O. Yu. , Kopchak V. M. , Khomiak I. V. , Khomiak A. I. , Malik A. V. 
Published: January 2021

Introduction. Up to date, no consensus exists on the surgical treatment of paraduodenal pancreatitis (PDP). Most authors prefer to perform pancreaticoduodenectomy when surgical treatment is indicated. However, such an aggressive approach may not always be justified for the treatment of benign disease. The aim of our study was to investigate the results of duodenum-preserving pancreatic head resections (DPPHR) for the treatment of PDP.
Materials and methods. We performed a retrospective analysis of a database consisting of 112 patients with PDP treated in Shalimov National Institute of Surgery and Transplantology from 2014 to 2019. A total of 45 patients after DPPHR were included to the study. Such modifications of DPPHR as Frey’s, Beger’s and Berne’s procedures were used. The primary study endpoint was pain control assessed according to the Izbicki pain score before surgery and at follow-up visits. Secondary endpoints were defined as complication rate (Clavien — Dindo >2), hospital length of stay and 90-day mortality. All patients were followed-up for the assessment of pain cessation with a median of 33 months (range 8–54 months).
Results. There were 42 males (93.3%) and 3 females (6.7%) in the study group. Preoperative Izbicki pain score result was 52.6 points. Follow-up pain score results were significantly lower at 11.7 points. Postoperative complication rate (Clavien — Dindo >2) was measured at 8.9%. Median hospital length of stay was 17.4 days. No mortality was recorded in the study group. All results were statistically significant (p<0.05).
Conclusion. Application of DPPHR for the surgical treatment of PDP allows to achieve excellent results in terms of pain control (52.6 and 11.7 points on the Izbicki pain score before surgical intervention and at follow-up), while maintaining low complication (8.9%) and mortality (0%) rates.
Bacterial overgrowth syndrome of upper parts of gastrointestinal tract in acute necrotizing pancreatitis
Authors: Rotar O. V. , Khomiak I. V. , Polioviy V. P. , Rotar V. I. 
Published: January 2021

Aim: to study the changes in the microflora of the upper part of digestive tract during acute necrotizing pancreatitis.
Material and methods. Acute necrotizing pancreatitis was induced in 42 white rats; changes in the mucous microflora of the upper part of digestive tract were studied. Bacteriological examination of the contents of the proximal small intestine was performed in 42 patients with acute necrotic pancreatitis during gastrofibroscopy.
Results and discussion. Induction of acute necrotic pancreatitis was accompanied by impaired colonization resistance of the intestinal mucosa due to the elimination of bifidobacteria and lactobacilli: the frequency of their growth from the mucosa decreased threefold (p<0.01), and the population level, respectively, by 25% (p<0.05) and by 36% (p<0.02). The mucosa was actively colonized by gram-negative pathogenic and conditionally pathogenic enterobacteria at high population level (3.07‒5.39 lg CFU/g), which allowed this microflora to overcome the damaged intestinal barrier and translocate. Pathogenic Escherichia spp. and Proteus spp. were cultivated from the mesenteric lymph nodes in 24 hours; Enterobacteria spp. and Staphylococci spp. were isolated from portal blood, pancreatic tissue, and peritoneal cavity 48 hours after induction of acute pancreatitis. Eight strains of gram-negative microorganisms were identified in small intestine in 69% of patients before surgery. Similar microflora was cultivated from pathological foci in 57.4% of patients after surgery.
Conclusion. Severe deficiency of autochthonous anaerobic microflora occurred in the upper parts of the digestive tract in acute necrotizing pancreatitis, causing excessive colonization by pathogenic and conditionally pathogenic microorganisms and promoting bacterial translocation.
Chronic pancreatitis: what should be considered in diagnosis, treatment, and prognosis
Authors: Khristich T. N. 
Published: January 2021

The aim of the literature review is to draw attention of doctors to the need of considering not only well-known etiological factors, but also pathogenetic ones that have an impact on the progression, chronicity of the process, treatment, prevention, and prognosis.
The role of alcohol, mechanism of obstruction of the pancreatic ducts in the occurrence of abdominal pain in chronic pancreatitis, and the development and progression of exocrine pancreatic insufficiency are discussed in detail.The issues of the onset of chronic pancreatitis in elder age, comorbidity with other diseases of the internal organs, with a lack of certain vitamins are considered. It is necessary to remember that exocrine insufficiency can be associated with the progression of glandular fibrosis, metabolic disorders, food intolerance, allergic syndrome, which provoke acute attacks.The author draws attention to the fact that the syndrome of inflammatory, enzymatic intoxication and the syndrome of disseminated intravascular coagulation should not be missed out in the acute nature of the process. Above-listed recommendations will help to correctly evaluate the clinical picture and prescribe the proper treatment, as well as to prevent the development of complicationsin time.
Klotho protein as a mediator of antioxidant defense in young people with gastroesophageal reflux disease and autoimmune thyroiditis
Authors: Pasiieshvili T. M. 
Published: January 2021

Aim: to establish the content and role of Klotho protein in the pathogenesis of gastroesophageal reflux disease, which occurs against the background of autoimmune inflammation in young people.
Materials and methods. Three groups of patients were involved in the study: with the gastroesophageal reflux disease (GERD ) and autoimmune thyroiditis (AIT ) (120 persons), isolated GERD (45) and AIT (42) aged 18 to 25 years, of the same sex and duration of the disease. The content of Klotho protein was determined in the serum by ELISA, Elabscience reagents (ELISA, USA).
Results. Significant increase in Klotho protein was detected in patients with GERD and especially in its combination with AIT relative to the control. Content of Klotho protein did not correlate with the morphological form of the disease and its duration. In patients with isolated AIT , Klotho protein level did not have a significant difference with control group.
Conclusion. The GERD and its combination with AIT in young people are accompanied by an increase in Klotho protein content, as a result of the presence of an active inflammatory process in the esophagus mucosa and its stimulating effect on antioxidant defense processes.
ДО ПИТАННЯ ЩОДО ПСИХОЛОГО-ПЕДАГОГІЧНОЇ КОМПЕТЕНТНОСТІ МАЙБУТНІХ ПЕДАГОГІВ ДОШКІЛЬНОЇ ОСВІТИ В СУЧАСНИХ УМОВАХ
Authors: Теличко Т. В. 
Published: January 2021

Стаття присвячена формуванню необхідних умінь і навичок грамотного вирішення педагогічних конфліктів та загальної психолого-педагогічної компетентності педагогів-вихователів. Визначено та охарактеризовано зміст, особливості та структуру психолого-педагогічної компетентності. Доведено, що психолого-педагогічна компетентність є однією з визначальних у структурі педагогічної діяльності сучасних педагогів закладів дошкільної освіти та складовою їхньої професійної компетентності. Практика показує, що необхідно розширити психолого-педагогічну підготовку вихователів закладів дошкільної освіти. Молодий педагог повинен уміти творчо співпрацювати з дітьми, батьками і з колегами; грамотно вирішувати конфліктні ситуації. А для цього необхідно засвоїти певний рівень теоретичних знань і практичних навичок поведінки в конфліктних ситуаціях, розробити необхідні рекомендації щодо попередження та вирішення конфліктних ситуацій для формування сприятливого морально-психологічного клімату.
Психолого-педагогічна компетентність передбачає узгодженість між психологічними, педагогічними та методичними знаннями, практичними вміннями і реальною поведінкою, яку педагог демонструє в процесі педагогічної взаємодії. Встановлено, що майбутні вихователі закладів дошкільної освіти часто переживають низку труднощів, пов’язаних із застосуванням досягнень психології у професійній практичній діяльності. Зазначено, що у відборі змісту матеріалу, що викладається, необхідно враховувати його наукову і практичну зорієнтованість. Це дає студентам розуміння практичної цінності психологічних знань та можливостей їхнього використання.
Parâmetros de indenização dos danos morais no Direito do Trabalho
Authors: De Azevedo Lopes Othon 
Published: January 2021

O presente artigo tem como objetivo analisar os parâmetros para quantificação das condenações por danos morais introduzidos pela Reforma Trabalhista (Lei nº 13.467/2017) e busca avaliar se estes parâmetros contribuem para a proteção simbólica da personalidade. O artigo se inicia com uma reconstrução histórica do instituto do dano moral e apresenta discussão sobre seu legado para nossa sociedade e para o Direito Privado. Em seguida, a reflexão situa os danos morais dentro do marco da proteção à dignidade humana e apresenta seus desdobramentos para os direitos da personalidade. Posteriormente, apresenta-se discussão jurídica sobre o instituto do dano moral individual e o papel das sanções de natureza civil, introduzidas historicamente pelo Direito Moderno, na proteção dos direitos da personalidade. Por fim, à luz das reflexões teóricas sobre o dano moral, o artigo avalia as inovações trazidas pela Reforma Trabalhista quanto aos parâmetros de quantificação dos danos morais e se tais inovações permitem interpretação conforme da legislação vigente sobre dano moral.

PALAVRAS-CHAVE: Dano moral. Direitos da Personalidade. Reforma Trabalhista. Critérios para fixação. Função preventiva fiduciária.
Mútuo consentimento
Authors: Coutinho Aldacy Rachid 
Published: January 2021

O presente artigo objetivo analisar criticamente a reforma trabalhista introduzida pela Lei 13.467, de 2017, pela introdução da possibilidade de distrato como forma de extinção do contrato de trabalho por acordo bilateral. O mútuo consentimento abre novas fronteiras no direito do trabalho para discussão sobre a possibilidade ou não de migração, pela transposição, de conceitos de direito civil, ultrapassados ou atuais, que se referem ao contrato e aos princípios da liberdade e autonomia da vontade ou privada. A delimitação das suas consequências no distrato acarreta o necessário controle do ato jurídico pela validade da manifestação do consentimento, com a observância da incidência de preceitos constitucionais que devem ser observados e a limitação decorrente da autonomia privada que não permite às partes contratantes a livre disposição dos efeitos decorrentes da emissão de vontade.

PALAVRAS-CHAVE: Direito do trabalho. Extinção do contrato. Distrato.
Determination of antibiotic residues in Black tiger shrimps (Penaeus monodon) and commercial shrimp feeds in Chattogram
Authors: Mahmood Sharjil , Sultana Nusrat , Mahmud Abdullah Al , Akter Sharmin , Kabir Md Hossain , Saha Suvanker 
Published: January 2021

Shrimps are good source of protein and also good exportable item for its quality all over the world. Inappropriate use of antibiotics in the production of local and export quality shrimps can facilitate infiltration of antibiotic residues into human bodies which are toxic enough to cause serious health hazard. The present study was investigated to determine the antibiotic residues in some selected local market and export quality shrimps and also commercial shrimp feeds in chattogram. Local grade and export grade samples of Black tiger shrimps (Penaeus monodon) and feeds of four different companies were taken for the completion of this study. The permissible residual limit for the shrimp samples were- 0.3(μg/kg) for Chloramphenicol and 1.0 (μg/kg) for AHD, AMOZ, SEM, AOZ. Black tiger shrimps from local market 1 had high concentration of Chloramphenicol (0.35 μg/kg) and SEM (1.2 μg/kg) residues whereas Market 2 showed maximum residues in AMOZ (1.2 μg/kg) and SEM (1.1 μg/kg). Whereas, Market 3 showed negative result. Local market 4 had high concentration of Chloramphenicol (0.4 μg/kg) and AOZ (1.2 μg/kg) residues. However, in export grade shrimps antibiotic residues was found under the maximum residual limit in all samples. Also, among four feed tested, two of them were found positive for chlorampenicol and nitrofurans. The result was considered significant where P>0.05. So, legal actions should be taken against the farmers and the farms that overuse antibiotics in shrimps. Also, people should be made aware of the harmful effects of antibiotics so that the impact can be minimized.
Asian J. Med. Biol. Res. December 2020, 6(4): 623-627
Effects of dietary polyunsaturated fatty acid on reproduction and developmental biology of Gangetic Mystus (Mystus cavasius) (Hamilton-Buchanan, 1822)
Authors: Akter Rafia , Ema Noore Safa , Hossain Md Saddam , Hossain Zakir 
Published: January 2021

The present study was undertaken to determine the effects of polyunsaturated fatty acids (PUFAs) on enhanced maturation, spawning, embryonic and larval development of endangered Gangetic Mystus (Mystus cavasius). Fishes were collected from the Brahmaputra River, Mymensingh, Bangladesh and stocked in the cisterns. Treated group was provided supplemental diet enriched with 1% squid extracted lipids as a source of PUFAs four months whereas controlled group fed the same diet except PUFAs. In comparison with the control group, treated group exhibited higher reproductive performances in spawning trial. The fertilization rate (79.5±1.49), hatching rate (72.29±1.78) and survival rate (64.31±0.48) of offspring were significantly higher in treated group compared to control. Consequently, early embryonic and larval development was observed in the treated fishes. Therefore, the present study indicates the enhanced reproductive and developmental performances of (Mystus cavasius) owing to PUFAs supplementation in diet.
Asian J. Med. Biol. Res. December 2020, 6(4): 641-649
Effect of different dietary protein level on growth, production and survivability of threatened Mystus cavasius (Hamilton-Buchanan 1822) in pond habitat
Authors: Samad Md Abdus , Alice Esmot Jahan , Pal Dipankar 
Published: January 2021

A study was undertaken to determine the effect of different dietary protein levels on growth, survival and production of Mystus cavasius (Hamilton-Buchanan 1822) with three experimental diets containing 29%, 32% and 35% protein level applied simultaneously to three treatments T1, T2 and T3 respectively each with three replications. The stocking density (1, 11, 150/ha), initial weight (3.00±00 g) and length (2.00±0.00 cm) of fish were same for all the treatments. No significant (P>0.05) difference was found for the mean values of water quality parameters. A suitable range of water quality parameters were recorded with the environment of experimental ponds. In terms of growth, production and survival, relatively highest performance was found in the treatment T3. After 180 days of rearing, average weight gain was 29.16±0.43 g, 31.17±0.30 g and 37.44±0.32 g with the above three different feeds, respectively. The average daily gain (ADG) and specific growth rate (SGR) of all treatments showed significant difference (P<0.05) and the highest value (0.21±0.04 and 1.43±0.01%) was found with the 35% dietary protein level containing diet. Feed conversion ratio (FCR) improved with increase of dietary protein. The findings of FCR were 2.97±0.02 at 29% protein level (T1), 2.64±0.02 at 32% protein level (T2) and 2.20±0.01 at 35% protein level (T3). The results of protein efficiency ratio (PER) values were fairly similar of 1.17±0.02 and 1.18±0.01 for 29% and 32% protein level containing diets respectively indicating low efficiency and the highest efficiency (1.30±0.01) was found with 35% protein level. The findings of condition factor in different treatments for Mystus cavasius were not significantly (P>0.05) varied with the treatments. Calculated values of condition factor were 1.04±0.00, 1.03±0.03 and 1.09±0.05 in treatment T1, T2 and treatment T3, respectively. In pond culture, the performance of treatment T3 was found to be better than the treatment T1 and T2. The production was of 3616±16.74 kg/ha in T3 during the culture period of six months. The best cost benefit ratio (CBR) value (1.98±0.02) was also found with treatment T3. The 35% dietary protein level with treatment T3 resulted in best growth performance and was probably adequate to meet the dietary protein needs of Mystus cavasius (Hamilton-Buchanan, 1822).
Asian J. Med. Biol. Res. December 2020, 6(4): 659-673
Management of hemodialysis unit in a specialized hospital
Authors: Sultana Arifa , Saha Ashees Kumar , Bilkis Afsana , Sultana Papia , Khatun Sajeda , Hossain Kazi Jahangir 
Published: January 2021

Chronic Kidney disease is becoming a global public health problem throughout the world. The aim of the study was to assess management status of the hemodialysis unit in a specialized hospital. It was a hospital based descriptive cross sectional study. A total of 17 participants were selected by purposive sampling method on the basis of defined selection criteria from January 2015 to December 2016. The place of study was National Institute of Kidney Diseases and Urology (NIKDU) hospital, Dhaka. The research instruments were a semi structured questionnaire and a checklist. The socio-demographic status of the respondents showed that 11.8 %( n=02) were doctor, 58.8 %( n=10) nurses and 29.4 %( n=05) were technician. Mean age of care providers was 38.82±8.79 years. Majority of respondents, were satisfied regarding the unit including physical facilities 76.5% (n=13) cleanliness of the unit 58.8% (n=10) and medical record facility 52.9% (n=9). Need to strengthen infection control measure and BCC activities among the service providers to improve the management status of the hemodialysis unit of NIKDU hospital.
Asian J. Med. Biol. Res. December 2020, 6(4): 683-688
Management of services in total quality management implemented and non-implemented health facilities
Authors: Begum Muhsina , Saha Ashees Kumar , Begum Sheuly , Akhter Nasima , Borua Pritikona , Riaz Baizid Khoorshid 
Published: January 2021

5S-CQI-TQM is a management technique that is aimed at bringing satisfaction of staff as well as the patients through improvement of working environment. A cross-sectional comparative study was carried out among 226 respondents who were selected purposively from the selected study place from 1st January to 31st December 2017. Among 226 respondents, 113 were taken from Dhaka Medical College and another 113 were taken from Mugdha Medical College. Among 113 respondents, 56 respondents were health care providers and 57 respondents were health care receivers. The purpose of this study to compare the management of services in Total Quality Management implemented (Dhaka Medical College and Hospital) and non-implemented (Mugdha Medical College and Hospital) health facilities. A Semi-structured interviewer administered questionnaire and an observational check list were developed to collect the data. Separate questionnaire was used for health care providers and health care receivers. The statistical analysis was conducted using SPSS (statistical package for social science) version 20 statistical software. Significant statistical differences were found between TQM implemented and TQM non-implemented hospital regarding workload (p=0.043), hospital authority always seriously consider staff’s suggestions for the improvement of quality of service (p<0.001), employees always respect to each other in the hospital (p<0.001) and 35 (62.5%) service providers expressed satisfactory opinion regarding management of the hospital.
Asian J. Med. Biol. Res. December 2020, 6(4): 689-696
Workplace environment and performance of nurses in a tertiary level hospital
Authors: Akhter Nasima , Saha Ashees Kumar , Ahmed Mst Jannat Ara , Begum Muhshina , Borua Priti Kana , Das Ringku , Haque Md Mahmudul 
Published: January 2021

Workplace environment is an integral part of a hospital. The workplace environment influences on nurses’ performance both positively and negatively. A cross-sectional study was conducted in Chittagong Medical College Hospital, Chittagong from 1st January to 31st December 2017 with the aim to assess the workplace environment and performance of nurses. Total respondents in this study were 210 nurses. Samples were selected by purposive sampling technique. After taking written consent from the respondents, data collection was done by face to face interview using a semi-structured questionnaire with the help of Copenhagen Psychosocial Questionnaire II and Performance Evaluation Rating Scale. Data were analyzed using SPSS. The study findings revealed that 43.3% had good, 51.4% average and 5.2% poor state of physical environment and 10.0% had good, 88.1% average and 1.9% poor state of psychosocial environment. Therefore 70.5% respondents’ performance needed some improvement. The results revealed that there was a significant relationship between educational qualification and workplace performance of nurses (p< 0.001; pulled from χ2 text) and psychosocial environment and workplace performance of nurses (p<0.015; pulled from χ2 text). So, a conducive workplace environment is very crucial in every hospital to improve nurses’ performance and provide quality care.
Asian J. Med. Biol. Res. December 2020, 6(4): 705-713
Medical record keeping practices in a tertiary level hospital
Authors: Barua Priti Kana , Saha Ashees Kumar , Borua Jay Priya , Barua Shampa , Akhter Nasima , Begum Muhsina , Das Ringku , Ahmed Be Nazir 
Published: January 2021

Medical record is the most important document in the medical field. This cross sectional study was conducted at Chittagong Medical College hospital from January to December, 2017 with the aim to assess the existing medical record keeping practices. Around 214 patients’ record files were selected by systematic sampling method and 30 record keeping personnel were also interviewed. Data were collected by review of records by observational checklist and semi-structured questionnaire were administered to medical record keeping personnel. This study showed that, out of 44 items of patient record file among them 33 items were recorded in 100%. Majority of the medical records (89.7%) were satisfactorily completed. All of the respondents mentioned that they had no training regarding medical record keeping practices. All the respondents stated that some problem faced during keeping the medical record and (90.0%) respondents stated that computerized medical record system could solve the problem they faced. This study showed that, the medical recording status is good in majority areas but keeping practice was not organized at all. There were important defects in keeping the medical records. It seems that there are multiple factors contributing to the problem, such as lack of manpower, insufficient record room and they had no training about medical record keeping practice. It is necessary for the government to develop policies and strategies to improve medical record keeping practice for patient safety, to reduce error, repetition of investigations, protect the medico legal issues and future health care advancement.
Asian J. Med. Biol. Res. December 2020, 6(4): 723-730