bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bacterial Normalized Binary Fission Growth Model
Authors: Baer Alan , Keady John P. 
Published: October 2021

AbstractMathematical models have traditionally been used to facilitate the interpretation of bacterial growth curves in order to more accurately understand and identify variations in bacterial proliferation. Here, a binary fission growth model was developed to normalize starting bacterial levels, allowing for the identification of changes in bacterial growth and the separation of a bacterial population as it correlates to size. This normalized binary fission model (NBF) relies on a multi-bin growth mode, where each bin is associated with a size range during a growth cycle. The proposed NBF model allows for a determination of the percentage of treated bacteria eradicated compared to a control sample, either generally across all bacterial binary fission sizes or specific to a size range or bin. Comparisons between the NBF model and experimental observations demonstrates that bacterial growth curves, and the ratio of sample growth to a control, can be used to both determine and normalize initial variations in bacterial size, and quantity, among test samples, as well as identify final nutrient levels and the percentage of bacteria affected by treatment.Significance StatementIt is difficult to determine the effectiveness of selective bacterial eradication based upon a bacteria’s characteristics size, related to acoustic resonance. Here we develop a binary fission model to analyze effect on growth curves of size depend eradications. Understanding the effect on growth curves provides a method to extract the eradication percentage and initial bacterial level differences between treated sample and control sample, by using the ratio of treated growth curve to control growth curve.
GRASP55 regulates mutant huntingtin unconventional secretion and aggregation
Authors: Ahat Erpan , Bui Sarah , Zhang Jianchao , da Veiga Leprevost Felipe , Sharkey Lisa , Reid Whitney , Nesvizhskii Alexey I. , Paulson Henry L. , Wang Yanzhuang 
Published: October 2021

AbstractRecent studies demonstrated that the Golgi stacking proteins, GRASPs, especially GRASP55, regulate Golgi-independent unconventional secretion, but the underlying mechanism remains unknown. Here, we used mutant huntingtin (Htt-Q74) as a model system to address this question. Our results demonstrate that Htt secretion is GRASP55- and autophagy-dependent, and is enhanced under stress conditions such as starvation and ER stress. Mechanistically, GRASP55 facilitates Htt secretion by tethering autophagosomes to lysosomes to promote autophagosome maturation and by stabilizing p23/TMED10, a channel for translocation of cytoplasmic proteins into the ERGIC lumen. Moreover, GRASP55 level is upregulated by various stresses to facilitate unconventional secretion, while inhibition of Htt-Q74 secretion by GRASP55 knockout enhances Htt aggregation and toxicity. Lastly, comprehensive secretomic analysis identified novel cargoes secreted by the same unconventional pathway, such as TAGLN, PAICS and PRDX1. This study provides important information on the role of GRASP55 in unconventional protein secretion and Huntington’s disease progression.
Robust transcriptional indicators of plant immune cell death revealed by spatio-temporal transcriptome analyses
Authors: Salguero-Linares Jose , Serrano Irene , Ruiz-Solani Nerea , Salas-Gómez Marta , Phukan Ujjal Jyoti , González Victor Manuel , Bernardo-Faura Martí , Valls Marc , Rengel David , Coll Nuria S. 
Published: October 2021

AbstractRecognition of a pathogen by the plant immune system often triggers a form of regulated cell death traditionally known as the hypersensitive response. This type of immune cell death occurs precisely at the site of pathogen recognition, and it is restricted to a few cells. Extensive research has shed light into how plant immune receptors are mechanistically activated. However, a central key question remains largely unresolved: how does cell death zonation take place and what are the mechanisms that underpin this phenomenon? As a consequence,bona fidetranscriptional indicators of immune cell death are lacking, which prevents gaining a deeper insight of its mechanisms before cell death becomes macroscopic and precludes any early or live observation. We addressed this question using the paradigmaticArabidopsis thaliana–Pseudomonas syringaepathosystem, by performing a spatio-temporally resolved gene expression analysis that compared infected cells that will undergo immune cell death upon pathogen recognitionvsby-stander cells that will stay alive and activate immunity. Our data revealed unique and time-dependent differences in the repertoire of differentially expressed genes, expression profiles and biological processes derived from tissue undergoing immune cell death and that of its surroundings. Further, we generated a pipeline based on concatenated pairwise comparisons between time, zone and treatment that enabled us to define 13 robust transcriptional immune cell death markers. Among these genes, the promoter of an uncharacterizedAAA-ATPasehas been used to obtain a fluorescent reporter transgenic line, which displays a strong spatio-temporally resolved signal specifically in cells that will later undergo pathogen-triggered cell death. In sum, this valuable set of genes can be used to define those cells that are destined to die upon infection with immune cell death-triggering bacteria, opening new avenues for specific and/or high-throughput techniques to study immune cell death processes at a single-cell level.
In plantadynamics, transport-biases and endogenous functions of mobile siRNAs inArabidopsis
Authors: Brosnan Christopher A. , Devers Emanuel A. , Sarazin Alexis , Lim Peiqi , Lehesranta Satu , Helariutta Yrjö , Voinnet Olivier 
Published: October 2021

ABSTRACTIn RNA interference (RNAi), small-interfering (si)RNAs processed from double-stranded RNA guide ARGONAUTE(AGO) proteins to silence sequence-complementary RNA/DNA. Plant RNAi can propagate locally and systemically, but despite recent mechanistic advances, basic questions/hurdles remain unaddressed. For instance, RNAi is inferred to diffuse through plasmodesmata, yet how its dynamicsin plantacompares with that of established symplastic-diffusion markers remains unknown. Also unknown is why select siRNA species, or size-classes thereof, are recovered in RNAi-recipient tissues, yet only under some experimental settings. Finally, RNAi shootward movement in micro-grafted Arabidopsis – necessary to study its presumptive transgenerational effects– has not been achieved thus far and endogenous functions of mobile RNAi remain scarcely documented.Focusing on non-amplified RNAi inArabidopsis, we show here that (i) transgenic RNAi-movement, although symplasmic, only partially recapitulates the diffusion pattern of free GFPin planta, (ii) the presence/absence of specific AGOs in incipient/traversed/recipient tissues likely explains the apparent siRNA-selectivity observed during vascular movement, (iii) stress application allows endo-siRNA translocation against the shoot-to-root phloem flow, and (iv) mobile endo-siRNAs generated from a single inverted-repeat(IR) locus, have the potential to regulate hundreds of transcripts.Our results close important knowledge-gaps, rationalize previously-noted inconsistencies between mobile RNAi settings, and provide a framework for functional endo-siRNA studies.
Does disclosure of earnings forecasts regulation affect the valuation of IPOs? Evidence from an emerging country
Authors: Ong Chui Zi , Mohd-Rashid Rasidah , Mehmood Waqas , Tajuddin Ahmad Hakimi 
Published: October 2021

PurposeThis paper aimed to explore the effect of a regulatory change pertaining to earnings forecasts disclosure from a mandatory to a voluntary regime on the valuation of Malaysian initial public offerings (IPOs).Design/methodology/approachThe study employed ordinary least square (OLS) regression and quantile regression to analyse the impact of disclosure of earnings forecasts regulation on the valuation of IPOs which comprised 458 IPOs reported for the period 2000–2017 on Bursa Malaysia.FindingsThis paper revealed that the regulatory change in forecasted earnings disclosure from a mandatory to a voluntary regime, effective from 1 February 2008, had a negative impact on the valuation of IPOs. The regime change did not improve the transparency of firms issuing IPOs. In fact, the absence of forecasted earnings information in most IPO prospectuses causedex anteuncertainties to increase. Voluntary disclosure, however, had a significant positive relationship with the valuation of the IPOs issued during the global financial crisis period (2008–2010). Firms concealed their poor qualities by excluding forecasted earnings information from their prospectuses in order to have a fair valuation.Practical implicationsThe findings may be used by policymakers as guidance in improving the existing regulation regarding the disclosure of forecasted earnings.Originality/valueThis paper provides new insight on the effect of a regulatory change pertaining to earnings forecasts disclosure from a mandatory to a voluntary regime on the valuation of Malaysian IPOs. It also provides evidence that the regulatory change of earnings forecast disclosure affects the IPOs' values listed during the global financial crisis period.
The technological acquisitions paradox in the beauty industry
Authors: Sedita Silvia Rita , Belussi Fiorenza , Noni Ivan De , Apa Roberta 
Published: October 2021

PurposeWe address the following research questions: (1) Is the innovation trajectory of the acquirer affected by previous acquisitions? (2) In which direction knowledge recombination from the acquisition is pushed further? (3) Is the technological acquisition more a means for knowledge exploration and radical innovation or, on the contrary, a way for consolidating previous technological specialization?Design/methodology/approachThe nature of this study is exploratory; therefore, we opted for an inductive approach based on the L'Oréal case study analysis. Data were triangulated from different sources: (a) the L'Oréal website and press releases collected in the 2009–2015 period; (b) journal articles and books on the global cosmetics industry and the insightful work of Jones (2010); (c) the Questel Orbit database containing data on patents; and (d) the Zephyr – Bureau van Dijk database containing information on the acquisitions of firms.FindingsEmpirical evidence from a patent data analysis reveals a paradoxical path. On the one hand, acquisitions enable the company to explore new technological spaces; on the other hand, they allow it to reinforce a preexisting technological trajectory, even when the knowledge base of the target is distant from that of the acquirer. Thus, in our case study, the absorption and recombination of knowledge from a variety of domains support specialization more than diversification technology strategies.Originality/valueWe add to innovation management literature a new perspective, by offering a detailed analysis, through patent data, of the knowledge recombination process, led by technological acquisitions.
Effects of trend inflation on monetary policy and fiscal policy shocks in Vietnam
Authors: Le Thanh Ha , Finch Nigel 
Published: October 2021

PurposeThis paper analyzes variations in the effects of monetary and fiscal shocks on responses of macroeconomic variables, determinacy region, and welfare costs due to changes in trend inflation.Design/methodology/approachThe authors develop the New-Keynesian model, in which the central banks can employ either nominal interest rate (IR rule) or money supply (MS rule) to conduct monetary policies. They also use their capital and recurrent spending budgets to conduct fiscal policies. By using the simulated method of moment (SMM) for parameter estimation, the authors characterize Vietnam's economy during 1996Q1–2015Q1.FindingsThe results report that consequences of monetary policy and fiscal policy shocks become more serious if there is a rise in trend inflation. Furthermore, the money supply might not be an effective instrument, and using the government budget for recurrent spending produces severe consequences in the high-trend inflation economy.Practical implicationsThis paper's findings are critical for economists and monetary and fiscal authorities in effectively designing both the monetary and fiscal policies in confronting the shift in the inflation targets.Originality/valueThis is the first paper that examines the effects of trend inflation on the monetary and fiscal policy implementation in the case of Vietnam.
Does transportation infrastructure impact economic growth in India?
Authors: Nenavath Sreenu 
Published: October 2021

PurposeThis paper aims to show a long run and causal association between economic growth and transport infrastructure.Design/methodology/approachIn this study, the authors use ARDL models through the period 1990 – 2020 to investigate the relationship between transport infrastructure and economic growth in India.FindingsThe infrastructure has a positive impact on economic growth in India for the long run. Moreover, Granger causality test demonstrates a unidirectional relationship between transport infrastructure to economic development. Stimulatingly, the paper highlights the effect of air infrastructure statistically insignificant on economic growth in the long and short-run period.Originality/valueThe original outcome from the study delivers an inclusive depiction of determinants of economic growth from transport infrastructure in India, and these findings will help the policymakers to frame policies to improve the transport infrastructure. Hence, it is proposed that the government of Indian should focus more to upsurge the transport infrastructure for higher economic development.
The Achilles tendon of dynamic pricing –– the effect of consumers' fairness preferences on platform's dynamic pricing strategies
Authors: Wang Yong , Tang Tianze , Zhang Weiyi , Sun Zhen , Xiong Qiaoqin 
Published: October 2021

PurposeIn this paper, the authors study the effect of consumers' fairness preferences on dynamic pricing strategies adopted by platforms in a non-cooperative game.Design/methodology/approachThis study applies fair game and repeated game theory.FindingsThis study reveals that, in a one-shot game, if consumers have fairness preferences, dynamic prices will slightly decline. In a repeated game, dynamic prices will be reduced even when consumers do not have fairness preferences. When fairness preferences and repeated game are considered simultaneously, dynamic prices are most likely to be set at fair prices. The authors also discuss the effect of platforms' discounting factors, the consumers' income and alternative choices of consumption on the dynamic prices.Research limitations/implicationsThe study findings illustrate the importance of incorporating behavioral elements in understanding and designing the dynamic pricing strategies for platforms and the implications on social welfare in general.Originality/valueThe authors developed a theoretical model to incorporate consumers' fairness preference into the decision-making process of platforms when they design the dynamic pricing strategies.
The differentiated role of organizational ambidexterity and organizational innovation in the subsidiary reverse knowledge transfer process
Authors: Borini Felipe Mendes , Santos Leandro Lima , Raziq Muhammad Mustafa , Pereira Rafael Morais , Brunhara Aldo José 
Published: October 2021

PurposeThis paper underscores how organizational ambidexterity and organizational innovation play differentiated roles in the subsidiary reverse knowledge transfers (RKT). The authors argue that both organizational ambidexterity and organizational innovation play a positive but differentiated role in the RKT process in that the former positively influences subsidiary knowledge creation, whereas the latter positively influences subsidiary knowledge transfers.Design/methodology/approachData were collected from 289 foreign subsidiaries operating in Brazil. Hypotheses were developed and tested by applying partial least squares structural equation modeling.FindingsThe results supported the hypotheses and showed that organizational ambidexterity promotes knowledge creation, and that organizational innovation facilitates knowledge transfers.Research limitations/implicationsThe paper offers implications with regard to drivers of subsidiary investments and actions of subsidiary managersvis-à-visthe subsidiary objectives of knowledge creation and/or transfers.Originality/valueShowing the different roles of organizational ambidexterity and organizational innovation, this paper reveals some underlying mechanisms of the RKT process and contributes by explaining the competitive heterogeneity of subsidiaries, with impacts on subsidiary management’s evolutionary and resource dependence perspective.
The myth of a direct relationship between organizational culture and TQM: propositions and challenges for research
Authors: Haffar Mohamed , Al-Hyari Khalil Ahmad , Djebarni Ramdane , Al-Shamali Ahmed , Abdul Aziz Muhammad , Al-Shamali Sarah 
Published: October 2021

PurposeThis paper aims to report the results of a comprehensive literature review concerned with exploring the distinctive roles of the underlying multidimensional psychological mechanisms through which organizational culture (OC) affects TQM.Design/methodology/approachA thorough review of the relevant existing studies focusing on the direct and indirect links between OC, employee readiness for change (ERFC), employee commitment to change (ECC) and TQM implementation was conducted. To identify studies to include in the review, electronic searches of prominent databases and journals were carried out for the period 1980 to 2020.FindingsThe thorough analysis of relevant studies indicates that various types of OC influence TQM through certain psychological mechanisms namely ERFC dimensions and employee affective commitment to change. As a consequence, the paper develops a set of propositions and a novel integrative conceptual framework to explain the mediating roles of ERFCs and EACC in the OC–TQM relationship and then concludes by suggesting future lines of research and highlighting practical managerial implications.Originality/valueDrawing on academic perspectives from multiple literature streams, this study offers a more advanced understanding of the relationship between OC and TQM implementation via exploring multiple mediating paths.
Performance evaluation of graphene added nanofluids and self-lubricating tools in machining Inconel 718
Authors: Maddamasetty Amrita , Bodduru Kamesh , Bevara Siva , Revuru Rukmini Srikant , Kumar Sanjay 
Published: October 2021

PurposeInconel 718 is difficult to machine due to its high toughness and study hardenability. Though the use of cutting fluids alleviates the problem, it is not sustainable. So, supply of a small quantity of specialized coolant to the machining zone or use of a solid lubricant is a possible solution. The purpose of the present work is to improve machinability of Inconel718 using graphene nanoplatelets.Design/methodology/approachIn the present study, graphene is used in the machining of Inconel 718 alloy. Graphene is applied in the following two forms: as a solid lubricant and as an inclusion in cutting fluid. Graphene-based self-lubricating tool and graphene added nanofluids are prepared and applied to turning of Inconel 718 at varying cutting velocities. Performances are compared by measuring cutting forces, cutting temperature, tool wear and surface roughness.FindingsGraphene, in both forms, showed superior performance compared to dry machining. In total, 0.3 Wt.% graphene added nanofluids showed the lowest cutting tool temperature and flank wear with 44.95% and 83.37% decrease, respectively, compared to dry machining and lowest surface roughness, 0.424 times compared to dry machining at 87 m/min.Originality/valueGraphene could improve the machinability of Inconel 718 when used in tools as a solid lubricant and also when used as a dispersant in cutting fluid. Graphene used as a dispersant in cutting fluid is found to be more effective.
Influence of glass powder incorporation on the physical-mechanical properties of sand concrete
Authors: Ammari Mohammed Seghir , Tobchi Mohammed Bachir , Amrani Yahia , Mim Anouer , Bederina Madani , Ferhat Ahmida 
Published: October 2021

Purpose
This study is part of the valorization of local materials and the reuse of industrial waste in construction. This study aims to improve the physical-mechanical properties of sand concrete. This work is a continuation of previous studies conducted on sand concrete, the purpose of which is to introduce industrial waste into this material. For this purpose, a glass waste in powder form is added.

Design/methodology/approach
This study is focused on the effect of adding glass powder (GP) whose mass percentage varies from 0 to 40% with an interval of 10% to target the right composition that ensures the best compromise between the characteristics studied.

Findings
The results found show that the workability and density of the studied concretes decreased with increasing GP dosage. Indeed, the optimal addition which constitutes the best compromise between the studied properties is 10% of GP. Improvements of up to about 9% in the case of flexural strength and about 18% in the case of compressive strength. The thermal conductivity has been reduced by 12.74%, the thermal diffusivity which characterizes the notion of thermal inertia has been reduced by about 4% and the specific heat mass has been reduced by 7.80%. Also, the shrinkage has been reduced by about 20%. The microstructure of the studied composite shows a good homogeneity between the aggregates. Finally, the addition of GP to sand concrete gives very encouraging results.

Originality/value
The interest of this study is in two parts. The first one is the exploitation of local materials: dune sand, river sand and limestone filler to meet the growing demand for construction materials. And the second one is the reuse of glass waste, in the form of powder (GP), to solve the environmental problem. All this participates in the improvement of the physical-mechanical properties of sand concrete and the extent of its response to the development of an economical structural concrete.
‘I Have Been a Collector of Costumes’: Women, Dress Histories and the Temporalities of Eighteenth‐Century Fashion
Authors: DYER SERENA 
Published: October 2021

AbstractBy the early nineteenth century, the ‘costume book’ genre was well established as a catalogue of national habits. These chronologically, socially and geographically devised sartorial indexes to the world strove to use dress as a means of categorising and delineating humankind. Such publications espouse a sense of neat chronological evolution, situated within a framework of masculine progress. While the majority of published costume books from the late eighteenth and early nineteenth centuries were authored by men, this article explores the myriad ways in which women too constructed, subverted and engaged in sartorial histories. Published dress histories attempted to use dress as a means of constructing a coherent chronological narrative of a national heritage. Yet amateur women, such as Catherine Hutton, Mary White and Laetitia Powell, used pens, scissors, paste and needles to reach back through that time‐tunnel, borrowing from and taking possession of the sartorial past.