bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of digital scanning and conventional impression taking for implant-supported prostheses
Authors: Studenikin R. V. , Mamedov A. A. 
Published: September 2021

The effect of discrepancies between digital scans and conventional impressions on the clinical performance of a permanent restoration has not been fully understood.Thirty patients received conventional impressions and digital scans of a single implant restoration. Two crowns were made for the same implant using both methods. The time taken for each procedure was recorded. After analyzing the accuracy and effectiveness of both crowns, the best one was placed. A questionnaire was conducted to assess the preferences and comfort when using crowns made by one method or another.The total time for the traditional impression technique was 15 minutes, while the time for the digital scanning technique was significantly less – 10 minutes.The preparation time, including the disinfection of the silicone impressions, their transportation to the laboratory, the casting of the impressions, the hardening of the plaster, as well as the preparation of the model by the technician, was 4 hours for conventional impressions.The timing for sending the STL file and modeling the structure was less than 2 hours for the digital scan method. The production time of crowns takes 3 hours for both conventional impressions and digital ones.Of all crowns selected for placement, 46.7% were made from conventional impressions and 53.3% from digital scans. Participants preferred the digital scanning technique (89%) over the traditional impression-taking technique (11%).The data from this study suggest that digital scanning and CAD/CAM technology may be more effective and better accepted by study par-ticipants for a single implant restoration than conventional impressions and plaster casts.
Systemic antimycotic therapy of patients with mycosis of the oral mucosa and periodontal Сandida etiology
Authors: Ushakov R. V. , Tsarev V. N. , Ushakova Т. V. , Tsareva Т. V. , Ushakov A. R. , Zavadsky R. V. , Eliseeva N. B. 
Published: September 2021

Candidiasis is the most common mycosis. Оral candidiasis occurs in the form of stomatitis, including the so-called prosthetic stomatitis. Somewhat less often, fungi of the genus Candida are detected with gingivitis and periodontitis, manifestations of red lichen planus on the oral mucosa.The purpose of the work: to analyze the results of mycological studies and determine the sensitivity of fungi isolated from the oral cavity in vari-ous oral pathologies to the main antimycotics, as well as the formation on this basis of an algorithm for antimycotic therapy of candidal lesions of the oral mucosa and periodontium.Material and methods. The paper uses the results of studies of patients with candidiasis of the oral mucosa (127 patients), prosthetic stomatitis (136 patients), candida-associated periodontitis (168 patients). Primary inoculation was performed quantitatively on Sabouraud’s medium and duplicated on M1297 chromogenic medium (Himedia Labs, India).To study the biofilm formed on the oral mucosa, fixed preparations of gold-coated scrapings were prepared for scanning electron microscopy, which was performed using a Quanta 200 3D bi-beam microscope (USA). Sensitivity to antimycotics was assessed using the traditional method of disks.The results of the study. When studying the species composition of yeast-like fungi isolated from the material, it was found that the species C. albicans was isolated in 80% of patients, in association with other species: C. Krusei, C. guilliermondii and C. glabrata. The second place was taken by the species C. Krusei, which was detected in 13.3% of patients. Representatives of this genus of yeast fungi are characterized by the formation of a biofilm with a pronounced mantle, which protects the microorganism from aggressive factors, including antimycotics and antiseptics. All the studied preparations showed fungicidal activity against these strains of yeast-like fungi. When registering the results, it was found that the most pronounced sensitivity of yeast-like fungi of this species was to drugs from the group of azole derivatives. The most pronounced antifungal activity was noted by us in voriconazole.Conclusion. Based on the obtained data, an algorithm of systemic antimycotic therapy for oral candidiasis has been developed.
Analysis of the lower jaw exoskeleton in finite element programs
Authors: D’yachenko D. Yu. , Vorob’ev A. A. , Makedonova Iu. A. , Kurkina О. N. , D’yachenko S. V. , Afanas’eva O. Yu. , Vargina S. A. 
Published: September 2021

A special place in the methods of surgical treatment of bone fractures is occupied by transosseous osteosynthesis using external fixation devices of various designs.Objective: to analyze the lower jaw exoskeleton in finite element programs.Materials and research methods. During the research, 36 human lower jaws were involved from the museum of the Department of Oper-ative Surgery and Topographic Anatomy of the Volgograd State Medical University. They were scanned in 3D. All obtained images were loaded into a virtual scene reconstruction program. Fractures of the lower jaws in the corner area were modeled, an apparatus for external fixation of the lower jaw exoskeleton was installed, and the chewing load on the lower jaw was simulated. The place of application of the force was an area on a small fragment of a repositioned 3D model of the mandibular bone corresponding to the place of attachment of the masseter muscle. The evaluation of virtual studies was carried out according to the results of the stress-strain states of the bones and apparatus, the schedule of displacements of objects and the results of the analysis of the safety factor.Research results and discussion. In the course of evaluating the virtual placement of the mini-fixator wires of the apparatus for external fixation of the lower jaw exoskeleton, it was revealed that the main load is applied to the mini-fixator wires on a large fragment and the bone in the area of the wires. For the possibility of precise positioning of the osteofixers of the external fixation device, a device for the safe installation of the spokes of the lower jaw exoskeleton was also developed.Conclusion. Thus, on the basis of computer mathematical analysis, it can be argued that the developed design of the apparatus for external fixation of the lower jaw exoskeleton works under conditions of the maxillofacial region, performs reposition and fixation of bone fragments of the lower jaw under conditions of chewing functioning of the restored fracture of the lower jaw.
Development of a device for safe spatial orientation of the spokes of an extra-focal osteosynthesis apparatus
Authors: D’yachenko D. Yu. , Vorob’ev A. A. , Makedonova Iu. A. , Kurkina О. N. , D’yachenko S. V. , Vargina S. A. 
Published: September 2021

A special place in the methods of surgical treatment of bone fractures is occupied by transosseous osteosynthesis using external fixation devices.The aim of the study is to develop a device for the safe spatial orientation of the wires of the extrafocal osteosynthesis apparatus.Materials and methods. To develop a device for the spatial orientation of the external fixation spokes, a 3D model was designed with further reproduction on a 3D printer. The development of the device was carried out by placing the wires of the external fixation apparatus on 36 bones of the human lower jaw, on which a fracture in the angle was simulated.Results and discussion. The device for the spatial orientation of the spokes of the external fixation device for the lower jaw exoselet is partially reproduced using a 3D printer, which allows individualizing the device parts at the stages of preparation for surgery.Conclusions. Effect: control of the depth of immersion of osteofixers over the entire thickness of the bone and simplification of the choice of the optimal angle of mutual spatial orientation during their introduction and the greatest stable fixation of the fragments of the lower jaw during closed extrafocal osteosynthesis.
Non-invasive Global and Regional Myocardial Work Predicts High-Risk Stable Coronary Artery Disease Patients With Normal Segmental Wall Motion and Left Ventricular Function
Authors: Zhang Jun , Liu Yani , Deng Youbin , Zhu Ying , Sun Ruiying , Lu Shirui 
Published: September 2021

Background: Previous studies suggested that myocardial work (MW) may identify abnormalities in the left ventricular (LV) function and establish a more sensitive index for LV dysfunction at the early stage. This study aimed to explore the value of global and regional MW parameters in predicting high-risk stable coronary artery disease (SCAD) patients with normal wall motion and preserved LV function.Patients and Methods: A total of 131 patients, who were clinically diagnosed as SCAD with normal wall motion and LV function, were finally included in this study. Global MW parameters, including global work index (GWI), global constructive work (GCW), global waste work (GWW), and global work efficiency (GWE) were measured with non-invasive LV pressure-strain loops constructed from speckle-tracking echocardiography. Regional myocardial work index (RWI) and work efficiency (RWE) were also calculated according to the perfusion territory of each major coronary artery. All patients underwent coronary angiography and were divided into the high-risk SCAD group, the non-high-risk SCAD group, and the No SCAD group according to the range and degrees of coronary arteries stenosis.Results: The global longitudinal strain (GLS), GWI and GCW were statistically different (P &lt; 0.001) among the three groups. In the high-risk SCAD group, GLS, GWI, and GCW were significantly lower than the other two groups (P &lt; 0.05). Receiver operating characteristic analysis demonstrated GWI and GCW could predict high-risk SCAD at a cutoff value of 1,808 mm Hg% (sensitivity, 52.6%; specificity, 87.8%; predictive positive value, 76.3%; predictive negative value, 69.9%) and 2,308 mm Hg% (sensitivity, 80.7%; specificity, 64.9%; predictive positive value, 63.3%; predictive negative value, 80.0%), respectively. Multivariate analyses showed that carotid plaque, decreased GWI, and GCW was independently related to high-risk SCAD. The cutoff values of RWILAD, RWILCX, and RWIRCA were 2,156, 1,929, and 1,983 mm Hg% in predicting high-risk SCAD, respectively (P &lt; 0.001). When we combined RWI in two or three perfusion regions, the diagnostic performance of SCAD was improved (P &lt; 0.001).Conclusions: Both global and regional MW parameters have great potential in non-invasively predicting high-risk SCAD patients with normal wall motion and preserved LV function, contributing to the early identification of high-risk patients who may benefit from revascularization therapy.
Clinical Molecular and Genomic Epidemiology of Morganella morganii in China
Authors: Xiang Guoxiu , Lan Kai , Cai Yimei , Liao Kang , Zhao Mei , Tao Jia , Ma Yi , Zeng Jianming , Zhang Weizheng , Wu Zhongwen , Yu Xuegao , Liu Yuyang , Lu Yang , Xu Caixia , Chen Liang , Tang Yi-Wei , Chen Cha , Jia Wei , Huang Bin 
Published: September 2021

Objectives:Ongoing acquisition of antimicrobial resistance genes has madeMorganella morganiia new clinical treatment challenge. Understanding the molecular epidemiology ofM. morganiiwill contribute to clinical treatment and prevention.Methods:We undertook a 6-year clinical molecular epidemiological investigation ofM. morganiifrom three tertiary hospitals in China since 2014. Antimicrobial susceptibility testing was performed using a VITEK-2 system. All isolates were screened for β-lactam and plasmid-mediated quinolone resistance genes by PCR. Isolates carrying carbapenem-resistant genes were subjected to whole-genome sequencing (WGS). The variation and evolution of these mobile genetic elements (MGEs) were then systematically analyzed.Results:Among allM. morganiiisolates (n= 335), forty (11.9%) were recognized as multidrug resistant strains.qnrD1,aac(6′)-Ib-cr,blaTEM–104, andblaCTX–M–162were the top four most prevalent resistance genes. Notably, phylogenomic and population structure analysis suggested clade 1 (rhierBAPS SC3 and SC5) associated with multiple resistance genes seemed to be widely spread. WGS showed ablaOXA–181-carrying IncX3 plasmid and aProteusgenomic island 2 variant carryingblaCTX–M–3,aac(6′)-Ib-crcoexisted in the same multidrug resistant strain zy_m28. Additionally, ablaIMP–1-carrying IncP-1β type plasmid was found in the strain nx_m63.Conclusion:This study indicates a clade ofM. morganiiis prone to acquire resistance genes, and multidrug resistantM. morganiiare increasing by harboring a variety of MGEs including two newly discovered ones in the species. We should be vigilant thatM. morganiimay bring more extensive and challenging antimicrobial resistance issue.
Positron Emission Tomography-Computed Tomography Parameters Predict Efficacy of Immunotherapy in Head and Neck Squamous Cell Carcinomas
Authors: Zhang Songtao , Zhang Runfang , Gong Wenbo , Wang Chao , Zeng Chen , Zhai Yifei , Fang Qigen , Dai Liyuan 
Published: September 2021

BackgroundThis study aims to assess the association between positron emission tomography-computed tomography (PET-CT) parameters and the response to immune checkpoint inhibitors in unresectable head and neck squamous cell carcinoma (HNSCC).MethodsA total of 105 patients receiving immunotherapy (pembrolizumab or sintilimab with/without cisplatin) were retrospectively enrolled in this study; pretreatment data regarding metabolic tumor volume (MTV) and maximum standardized uptake value (SUVmax) were collected. The primary interest of the study was objective response rate (ORR), and the secondary was progression−free survival (PFS).ResultsThe mean total MTV was 40.6 cm3 (range: 8.5–100.3), ORRs in tumors with total MTV of ≥40.6 and &lt;40.6 cm3 were 43.1% and 23.1%, respectively; the difference was statistically significant (p = 0.018). Survival analysis indicated similar PFS rates in the two groups (p = 0.057). The mean total SUVmax was 12.5, ORRs in tumors with total SUVmax ≥12.5 and &lt;12.5 were 40.0% and 26.0%, respectively; the difference was not significant (p = 0.092). Survival analysis reported patients with total SUVmax of ≥12.5 had significantly worse PFS (p = 0.001) than patients with total SUVmax of &lt;12.5.ConclusionsIn HNSCC, total MTV ≥40.6 cm3 translated into improved clinical response but not into better PFS; total SUVmax had no effect on clinical response, but total SUVmax ≥12.5 was associated with worse PFS.
A Study on the Correlations of Anxiety and Depression With Self-Management Ability and Endogenous Creatinine Clearance Rate in Renal Transplant Recipients
Authors: Hu ShiMin , Li Yu , Quan MingTao , Yang ShuJuan , Wan ZhaoMei , Yan XiaoYong , Tan ZhouKe , Liang GuoBiao 
Published: September 2021

Objective: To explore the effects of anxiety and depression on the self-management ability and endogenous creatinine clearance rate of renal transplant patients.Method: Eighty-eight renal transplant recipients who were followed up in the outpatient clinic of the Affiliated Hospital of Zunyi Medical University were selected using convenient sampling. The self-made general data sheet, Self-Rating Anxiety Scale, Self-Rating Depression Scale, and Self-Management Scale for Kidney Transplant Recipients were used. Correlation analysis was used to find factors related to endogenous creatinine clearance, while multiple linear regression was used to identify factors influencing endogenous creatinine clearance. Patients with or without anxiety and depression were divided into groups, and the indexes of the groups were compared using the independent samples t test, rank-sum test, or chi-squared test.Results: Anxiety was present in 12.5% of patients, depression in 25%, and a moderate level of self-management in 34.1%. Only 9.1% of renal transplant recipients had endogenous creatinine clearance within the normal range, and 34.1% had a body mass index not in the normal range (25% were overweight, and 9.1% were underweight). The endogenous creatinine clearance rate was negatively correlated with age and degree of depression, and positively correlated with body mass index, treatment management score, and psychosocial management score. The main influencing factors of endogenous creatinine clearance rate were age, sex, depression, body mass index, and treatment management score. The endogenous creatinine clearance rate and psychosocial management ability were significantly higher in patients without anxiety and depression than in patients with anxiety and depression (all P &lt; 0.05).Conclusions: Anxiety and depression showed significant negative effects on the psychosocial self-management ability and endogenous creatinine clearance rate of renal transplant recipients and thus should be given more attention.
ANALYSIS OF THE STATE OF SERVICEABILITY IN THE PROCESS OF WEAR OF ELEMENTS DURING THE OPERATION OF OIL AND GAS PRODUCTION EQUIPMENT
Authors: Sevda Aliyeva Sevda Aliyeva 
Published: September 2021

The generalized indicator of useful use, depending on the state of individual elements of oil-producing equipment, characterizes the ability of this equipment to perform its function during operation at optimal working time. The generalized indicator of the useful use of operational equipment can be described as the calculated sum of the indicator of the useful use of individual equipment elements. If, during operation, the oil-producing equipment retains its operability due to frequent replacement of its structural and non-structural elements, then such operational equipment is considered by users as outdated.
Operating equipment can be divided into 6 categories according to the indicators of suitability. The article analyzes the state of useful use of equipment and, as a result, the total utility of equipment is calculated in accordance with the indicators of useful use by category, and graphs of changes in the state of useful use are constructed. Based on the study of the graphs of the useful use of equipment, it was proposed to conduct an analysis in the following areas:
•	Evaluation of the design and technological perfection of the equipment by users according to important new parameters.
•	Determination of equipment compliance with wear standards during operation.
Keywords: structural element, wear theory, the usefulness of jam, categories, schedule of changes, reliability.
D.C. Magnetron Sputtering Coating on Trenches
Authors: V Srikumaran 
Published: September 2021

The development and application of plasma processing such as plasma assisted CVD and PVD become highly important in various industrial fields such as microelectronics, sensors, solar cells, automobiles, cutting tools, etc. In PVD different process are used such as Vacuum Evaporation, Electron Beam evaporation, Sputtering etc. But all processes have common limitation of one as such deposition is inline sight. It is difficult to achieve uniform coating on complex surfaces, holes and trenches. The width dimension and higher aspect ratio (Depth: width >1) of trenches generally in compatible with sputter deposition. When aspect ratio is increased, undesirable discontinuity can be observed at the lower half compared to upper half of trenches. So that 3 axis rotation of substrate holder was designed with a stepper motors to get uniform coating on complex surfaces and holes. The angle of rotation and the speed are controlled by programmed micro controller. By positioning the surface features perpendicular to the plasma the holes, grooves are coated uniformly. The coating was characterized using X-ray diffractometer, SEM and micro hardness tester.
ENERGY SAVING IN ORGANIZATION OF HEATING IN THE PRODUCTION OF BROILERS
Authors: Агафонова Ирина Владимировна 
Published: September 2021

Статья посвящена значению энергосбережения в системах отопления на птицефабриках. Автором выполнено сравнение эффективности энергоснабжения бройлерного производства при применении различных систем отопления. В статье приведен сравнительный расчет генераторов тепла на газе и инфракрасных излучателей для птицефабрики, находящейся в городе Йошкар Ола.
The article is devoted to the importance of energy saving in heating systems at poultry farms. The author compares the efficiency of energy supply of broiler production when using different heating systems. The article provides a comparative calculation of gas heat generators and infrared emitters for a poultry farm located in the city of Yoshkar Ola.
CORPORATE TRAINING AS AN ELEMENT OF THE PERSONNEL MANAGEMENT SYSTEMPRINCIPLES OF MANAGING INNOVATIVE ACTIVITIES IN EDUCATION
Authors: Булавко Ольга Александровна 
Published: September 2021

Рассматривается сущность, виды корпоративного обучения, значимость в системе управления персоналом предприятия.
The essence, types of corporate training, the significance in the personnel management system of the enterprise are considered.
ORGANIZATION OF PROSECUTOR'S SUPERVISION OVER THE IMPLEMENTATION OF LAWS DURING THE REGISTRATION, CONSIDERATION AND RESOLUTION OF REPORTS ON CRIMES OF EXTREMIST DIRECTIONS
Authors: Шинкарук Владимир Маркович , Фантров Павел Петрович , Соловьева Наталья Алексеевна 
Published: September 2021

В статье описаны основные особенности организации прокурорского надзора за исполнением законов при приеме, регистрации и разрешении сообщений о преступлениях экстремистской направленности. Дается характеристика полномочий прокурора в контексте исполнения им законодательства о противодействии экстремизму.
The article describes the main features of the organization of prosecutorial supervision over the execution of laws when receiving, registering and resolving reports on extremist crimes. The authors describe the powers of the prosecutor in the context of his execution of the legislation on countering extremism.
BASIC DETERMINANTS CONDITIONING THE PERFORMANCE YOUTH PUBLIC CALLS FOR EXTREMIST ACTIVITIES
Authors: Фантров Павел Петрович , Шинкарук Владимир Маркович 
Published: September 2021

В статье описаны основные причины, побуждающие молодежь к публичным призывам к осуществлению экстремистской деятельности. Авторы статьи выделяют следующие из них: социально-экономические, политические, идеологические и религиозные. В целях обеспечения общественной безопасности необходимо нивелирование экстремистских настроений в молодежной среде.
The article describes the reasons prompting young people to make public calls to carry out extremist activities. The authors of the article highlight the following of them: socio-economic, political, ideological and religious. In order to ensure public safety, it is necessary to level out extremist sentiments in the youth environment.
THE STUDY OF THE FACTORS DETERMINING THE OPERATIONAL EFFICIENCY OF THE SOCIO-ECONOMIC SYSTEM
Authors: Богомолова Елена Владимировна 
Published: September 2021

Современные предпринимательские структуры представляют собой открытые социально-экономические системы. Деятельность такой системы определяется рядом характеристик, одной из которых является операционная эффективность. Улучшая уровень операционной эффективности социально-экономическая системы может достигнуть конкурентных преимуществ на рынке.
Modern entrepreneurial structures are open socio-economic systems. The activity of such a system is determined by a number of characteristics, one of which is operational efficiency. By improving the level of operational efficiency, the socio-economic system can achieve a competitive advantage in the market.
PRINCIPLES OF MANAGING INNOVATIVE ACTIVITIES IN EDUCATION
Authors: Туктарова Лилия Равильевна 
Published: September 2021

Рассматриваются вопросы и положения инновационной деятельности в образовании, приведены основные критерии инноваций в образовании.
The issues and provisions of innovation in education are considered, the main criteria for innovation in education are given.