bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemically Enhanced Solid–Liquid Separation of Digestate: Suspended Solids Removal and Effects on Environmental Quality of Separated Fractions
Authors: Beggio Giovanni , Peng Wei , Lü Fan , Cerasaro Andrea , Bonato Tiziano , Pivato Alberto 
Published: October 2021

AbstractChemically enhanced solid–liquid separation (CES) of digestate can improve its membrane filterability but potentially influence the environmental features of the separated solid fraction, thus hindering its possible agricultural reuse. In this study, the effects were assessed of different dosages of polyaluminum chloride (PAC), epichlorohydrine-dimethylamine with ethylendiamine (DEED) and polyacrilamides (PAM) on CES of digestate from biowaste in terms of Total Suspended Solid (TSS) mitigation in the liquid fractions and resulting environmental quality of the solid fractions. Results from lab-scale trials showed that applied chemicals significantly increased the centrifugation efficiency with achieving minimum TSS concentration of 2347 ± 281 mgTSS/L (up to 90% improved TSS mitigation). Also, performed treatments led to almost complete removal of P and Heavy Metals (HMs) from the liquid fractions after centrifugation. Conditioned solid fractions showed higher Al (reaching 20 g kg−1 TS), organic carbon and nitrogen content (up to 324 mgTOC kg−1 TS and 44.1 mgTKN kg−1 TS, respectively) due to residual PAC, DEED and PAM. However, achieved concentrations of HMs guaranteed full consistency with EU regulation limits established for agricultural reuse of organic soil amendments. Further, leaching tests performed on the treated solid fractions indicate higher chlorides and soluble Al concentrations in the water extracts (up to 4.6 g L−1 and 2.3 g L−1, respectively), but lower HMs leachability from the digestates undergone CES. Nevertheless, water extracts from treated biosolids were characterized by higher phytotoxicity, likely related with direct Al toxicity and increased salinity due to chemicals addition. Accordingly, the effects on soil–plant system should be better investigated when agricultural reuse of CES-treated solid fraction of digestate is foreseen.
Graphic abstract
Artificial Intelligence: Mind, Computer and the Dance of the Wu Li Masters
Authors: Siekmann Jörg 
Published: October 2021

AbstractIn these days of exuberant fantasies about the future development of artificial intelligence—mostly written by people who have never in their lives developed an AI program—the GFFT (Society for the Promotion of Technology Transfer) has also unleashed a competition on future AI scenarios to honour Wolfgang Bibel. Because I was allowed to give the laudatory speech for Wolfgang, I was also asked to contribute something to the pen. And because, despite everything else, it is not reprehensible to think about the future, I could not refrain from doing so. Here is my somewhat expanded contribution.
How Teacher and Grammarly Feedback Complement One Another in Myanmar EFL Students’ Writing
Authors: Thi Nang Kham , Nikolov Marianne 
Published: October 2021

AbstractProviding feedback on students’ writing is considered important by both writing teachers and students. However, contextual constraints including excess workloads and large classes pose major and recurrent challenges for teachers. To lighten the feedback burden, teachers can take advantage of a range of automated feedback tools. This paper investigated how automated feedback can be integrated into traditional teacher feedback by analyzing the focus of teacher and Grammarly feedback through a written feedback analysis of language- and content-related issues. This inquiry considered whether and how successfully students exploited feedback from different sources in their revisions and how the feedback provisions helped improve their writing performance. The study sample of texts was made up of 216 argumentative and narrative essays written by 27 low-intermediate level students at a Myanmar university over a 13-week semester. By analyzing data from the feedback analysis, we found that Grammarly provided feedback on surface-level errors, whereas teacher feedback covered both lower- and higher-level writing concerns, suggesting a potential for integration. The results from the revision analysis and pre- and post-tests suggested that students made effective use of the feedback received, and their writing performance improved according to the assessment criteria. The data were triangulated with self-assessment questionnaires regarding students’ emic perspectives on how useful they found the feedback. The pedagogical implications for integrating automated and teacher feedback are presented.
An optimal nuclei segmentation method based on enhanced multi-objective GWO
Authors: Sharma Ravi , Sharma Kapil 
Published: October 2021

AbstractIn breast cancer image analysis, reliable segmentation of the nuclei is still an open-ended research problem. In this paper, a new clustering-based nuclei segmentation method is presented. First, the proposed method pre-processes the histopathology image through SLIC method. Then, a novel variant of multi-objective grey wolf optimizer is employed to group the obtained super-pixels into optimal clusters. Lastly, the optimal cluster with minimum value is segmented as the nuclei region. The experimental results demonstrates that the proposed variant of multi-objective grey wolf algorithm surpasses the existing multi-objective algorithms over ten standard multi-objective benchmark functions belonging to different categories. Particularly, the proposed variant has achieved best fitness value of more than 0.90 on 90% of the considered functions. Further, the nuclei segmentation accuracy of the proposed method is validated on H&E-stained estrogen receptor positive (ER+) breast cancer images. Experimental results illustrates that the proposed method has attained dice-coefficient value of more than 0.52 on 80% of the images. This illustrates that the proposed method is efficient in producing efficacious segmenting over histology images of Breast cancer.
Reflecting on reflection: prospect theory, our behaviors, and our environment
Authors: Oliver Adam 
Published: October 2021

AbstractIn a previously published article, I reported some tests of prospect theory's reflection effect over outcomes defined by money and life years gained from treatment. Those results suggested qualified support for the reflection effect over money outcomes and strong support over longevity outcomes. This article reruns those tests while accounting for the intensity of individual risk attitudes, and, overall, show consistency with the reflection effect. However, I argue that these results do not necessarily offer support for the explanatory power of prospect theory. Rather, the results may be driven by evolved responses to circumstances that provoke perceptions of scarcity and abundance. Therefore, from an ecological perspective, behavioral patterns such as those that are consistent with the reflection effect, which, by extension, tend to be considered as erroneous or biased by most behavioral economists because they conflict with the postulates of rational choice theory, may not be unreasonable. Recognizing as such is important when considering how behavioral insights ought to inform public policy design and implementation.
Waves in the gas centrifuge: asymptotic theory and similarities with the atmosphere
Authors: Rodal Marie , Schlutow Mark 
Published: October 2021

We study the stratified gas in a rapidly rotating centrifuge as a model for the Earth's atmosphere. Based on methods of perturbation theory, it is shown that in certain regimes, internal waves in the gas centrifuge have the same dispersion relation to leading order as their atmospheric siblings. Assuming an air filled centrifuge with a radius of around 50 cm, the optimal rotational frequency for realistic atmosphere-like waves is around 10 000 revolutions per minute. Using gases of lower heat capacities at constant pressure, such as xenon, the rotational frequencies can be even halved to obtain the same results. Similar to the atmosphere, it is feasible in the gas centrifuge to generate a clear scale separation of wave frequencies and therefore phase speeds between acoustic waves and internal waves. In addition to the centrifugal force, the Coriolis force acts in the same plane. However, its influence on axially homogeneous internal waves appears only as a higher-order correction. We conclude that the gas centrifuge provides an unprecedented opportunity to investigate atmospheric internal waves experimentally with a compressible working fluid.
Comparison of Objective Prognostic Score and Palliative Prognostic Score performance in inpatients with advanced cancer in Japan and Korea
Authors: Hiratsuka Yusuke , Kim Daye , Suh Sang-Yeon , Kim Sun-Hyun , Yoon Seok-Joon , Koh Su-Jin , Park Shin Ae , Seo Ji-Yeon , Kwon Jung Hye , Park Jeanno , Park Youngmin , Hwang Sun Wook , Lee Eon Sook , Choi Hana , Ahn Hong-Yup , Cheng Shao-Yi , Chen Ping-Jen , Yamaguchi Takashi , Morita Tatsuya , Tsuneto Satoru , Mori Masanori , Inoue Akira ,   EASED Investigators
Published: October 2021

Abstract

Objective
Accurate prognostication is important for patients and their families to prepare for the end of life. Objective Prognostic Score (OPS) is an easy-to-use tool that does not require the clinicians’ prediction of survival (CPS), whereas Palliative Prognostic Score (PaP) needs CPS. Thus, inexperienced clinicians may hesitate to use PaP. We aimed to evaluate the accuracy of OPS compared with PaP in inpatients in palliative care units (PCUs) in three East Asian countries.

Method
This study was a secondary analysis of a cross-cultural, multicenter cohort study. We enrolled inpatients with far-advanced cancer in PCUs in Japan, Korea, and Taiwan from 2017 to 2018. We calculated the area under the receiver operating characteristics (AUROC) curve to compare the accuracy of OPS and PaP.

Results
A total of 1,628 inpatients in 33 PCUs in Japan and Korea were analyzed. OPS and PaP were calculated in 71.7% of the Japanese patients and 80.0% of the Korean patients. In Taiwan, PaP was calculated for 81.6% of the patients. The AUROC for 3-week survival was 0.74 for OPS in Japan, 0.68 for OPS in Korea, 0.80 for PaP in Japan, and 0.73 for PaP in Korea. The AUROC for 30-day survival was 0.70 for OPS in Japan, 0.71 for OPS in Korea, 0.79 for PaP in Japan, and 0.74 for PaP in Korea.

Significance of results
Both OPS and PaP showed good performance in Japan and Korea. Compared with PaP, OPS could be more useful for inexperienced physicians who hesitate to estimate CPS.
Cost-effective millimeter-wave measurement setup for narrowband path loss and angle-of-arrival measurements: uncertainty analysis and specular building reflection measurements
Authors: Schulpen R. , Bronckers L. A. , Smolders A. B. , Johannsen U. 
Published: October 2021

AbstractA cost-effective millimeter-wave measurement setup for narrowband path loss and angle-of-arrival measurements is presented in this paper. The setup consists of ubiquitous radio-frequency lab equipment and additional low-cost components. An algorithm is developed, which improves the measurement accuracy and reduces the required measurement time. An uncertainty analysis is performed, including a noise analysis, amplifier linearity, antenna misalignment and general system impairments. A theoretical model of the received signal plus noise is developed, which is used in Monte Carlo simulations to show the impact of snapshot averaging on the uncertainty. The estimated combined uncertainty with a 95.45% confidence level is 1.1 dB at the maximum measurable path loss and 0.3 dB in the case of low path loss, where the uncertainty due to receiver noise is negligible. The measurement setup is used in outdoor specular building reflection measurements at 24.00–24.25 GHz. The measured single-building reflections show a 1–9 dB excess loss compared to the free-space path loss. The measured excess loss is 9–20 dB for double-building reflections. These results indicate that buildings could potentially be used as effective millimeter-wave specular reflectors to extend millimeter-wave coverage.
Global Wet/Dry Patterns and Mechanisms Since the Last Glacial Maximum: A Key to Future Projection
Authors: Li Yu , Zhang Yuxin , Ye Wangting , Zhang Xinzhong 
Published: October 2021

AbstractInvestigating the response mechanisms of long‐term global wet/dry pattern changes to cold/warm periods and climate forcings can provide scientific supports for the projection of future wet/dry patterns in the context of global warming. Here we present a systematic assessment into the response of global wet/dry patterns to cold/warm periods since the Last Glacial Maximum, and test the triggers for global wet/dry status change. Then we conduct an assessment of future global wet/dry patterns based on a thorough analysis of modern observations, paleoclimate simulations and records. Results show that regions following the hypothesis of “wet gets wetter, dry gets drier” (WWDD) account for 22.81% of the world's land area except Antarctica in the future. Regions complied with future “DD” pattern mostly concentrate in the parts of southwestern North America, southwestern South America, Mediterranean, northern Africa, southern Africa and Asia, covering 18.21% of the modern dry regions. Regions complied with future “WW” pattern occupy 25.41% of the modern wet regions, mainly distributing around the parts of northeastern South America, central Africa, western Russia, eastern Asia and northeastern Australia. Besides we investigate global wet/dry patterns during the abrupt climate change and find that global wet/dry patterns generally have the opposite status between abrupt warm and cold periods. If an abrupt cold event appears in the near warm future, it is likely that some parts of southwestern North America and Mediterranean in modern dry regions will be getting wet.
Tracing Carbonate Formation, Serpentinization, and Biological Materials With Micro‐/Meso‐Scale Infrared Imaging Spectroscopy in a Mars Analog System, Samail Ophiolite, Oman
Authors: Leask Ellen K. , Ehlmann Bethany L. , Greenberger Rebecca N. , Pinet Patrick , Daydou Yves , Ceuleneer Georges , Kelemen Peter 
Published: October 2021

AbstractVisible‐shortwave infrared (VSWIR) imaging spectrometers map composition remotely with spatial context, typically at many meters‐scale from orbital and airborne data. Here, we evaluate VSWIR imaging spectroscopy capabilities at centimeters to sub‐millimeter scale at the Samail Ophiolite, Oman, where mafic and ultramafic lithologies and their alteration products, including serpentine and carbonates, are exposed in a semi‐arid environment, analogous to similar mineral associations observed from Mars orbit that will be explored by the Mars‐2020 rover. At outcrop and hand specimen scales, VSWIR spectroscopy (a) identifies cross‐cutting veins of calcite, dolomite, magnesite, serpentine, and chlorite that record pathways and time‐order of multiple alteration events of changing fluid composition; (b) detects small‐scale, partially altered remnant pyroxenes and localized epidote and prehnite that indicate protolith composition and temperatures and pressures of multiple generations of faulting and alteration, respectively; and (c) discriminates between spectrally similar carbonate and serpentine phases and carbonate solid solutions. In natural magnesite veins, minor amounts of ferrous iron can appear similar to olivine's strong 1‐μm absorption, though no olivine is present. We also find that mineral identification for carbonate and serpentine in mixtures with each other is strongly scale‐ and texture‐dependent; ∼40 area% dolomite in mm‐scale veins at one serpentinite outcrop and ∼18 area% serpentine in a calcite‐rich travertine outcrop are not discriminated until spatial scales of <∼1–2 cm/pixel. We found biological materials, for example bacterial mats versus vascular plants, are differentiated using wavelengths <1 μm while shortwave infrared wavelengths >1 μm are required to identify most organic materials and distinguish most mineral phases.
On the Damping Time Scale of EVP Sea Ice Dynamics
Authors: Danilov Sergey , Koldunov Nikolay V. , Sidorenko Dmitry , Scholz Patrick , Wang Qiang 
Published: October 2021

AbstractWe propose to make the damping time scale, which governs the decay of pseudo‐elastic waves in the Elastic Viscous Plastic (EVP) sea‐ice solvers, independent of the external time step and large enough to warrant numerical stability for a moderate number of internal time steps. A necessary condition is that the forcing on sea ice varies slowly on the damping time scale, in which case an EVP solution may still approach a Viscous Plastic one, but on a time scale longer than a single external time step. In this case, the EVP method becomes very close to the recently proposed modified EVP (mEVP) method in terms of stability and simulated behavior. In a simple test case dealing with sea ice breaking under the forcing of a moving cyclone, the EVP method with an enlarged damping time scale can simulate linear kinematic features which are very similar to those from the traditional EVP implementation, although a much smaller number of internal time steps is used. There is more difference in sea‐ice thickness and linear kinematic features simulated in a realistic Arctic configuration between using the traditional and our suggested choices of EVP damping time scales, but it is minor considering model uncertainties associated with choices of many other parameters in sea‐ice models.
Representing Microphysical Uncertainty in Convective‐Scale Data Assimilation Using Additive Noise
Authors: Feng Yuxuan , Janjić Tijana , Zeng Yuefei , Seifert Axel , Min Jinzhong 
Published: October 2021

AbstractFor convective clouds and precipitation, model uncertainty in cloud microphysics is considered one of the most significant sources of model error. In this study, samples for model microphysical uncertainty are obtained by calculating the differences between simulations equipped with two‐ and one‐moment schemes during a one‐month training period. The samples are then added to convective‐scale ensemble data assimilation as additive noise and combined with large‐scale additive noise based on samples from climatological atmospheric background error covariance. Two experiments, including the combination and large‐scale error only, are conducted for a one‐week convective period. The results reveal that the simulation with a two‐moment scheme triggers more convection and has larger ice‐phase precipitation particles, which produce a stronger signal in the melting layer. During data assimilation cycling, although more water is introduced to the model, it is shown that the combination performs better for both background and analysis and significantly improves short‐term ensemble forecasts of radar reflectivity and hourly precipitation.
Targeting the miRNA-155/TNFSF10 network restrains inflammatory response in the retina in a mouse model of Alzheimer’s disease
Authors: Burgaletto Chiara , Platania Chiara Bianca Maria , Di Benedetto Giulia , Munafò Antonio , Giurdanella Giovanni , Federico Concetta , Caltabiano Rosario , Saccone Salvatore , Conti Federica , Bernardini Renato , Bucolo Claudio , Cantarella Giuseppina 
Published: October 2021

AbstractAge-related disorders, such as Alzheimer’s disease (AD) and age-related macular degeneration (AMD) share common features such as amyloid-β (Aβ) protein accumulation. Retinal deposition of Aβ aggregates in AMD patients has suggested a potential link between AMD and AD. In the present study, we analyzed the expression pattern of a focused set of miRNAs, previously found to be involved in both AD and AMD, in the retina of a triple transgenic mouse model of AD (3xTg-AD) at different time-points. Several miRNAs were differentially expressed in the retina of 3xTg-AD mice, compared to the retina of age-matched wild-type (WT) mice. In particular, bioinformatic analysis revealed that miR-155 had a central role in miRNA-gene network stability, regulating several pathways, including apoptotic and inflammatory signaling pathways modulated by TNF-related apoptosis-inducing ligand (TNFSF10). We showed that chronic treatment of 3xTg-AD mice with an anti-TNFSF10 monoclonal antibody was able to inhibit the retinal expression of miR-155, which inversely correlated with the expression of its molecular target SOCS-1. Moreover, the fine-tuned mechanism related to TNFSF10 immunoneutralization was tightly linked to modulation of TNFSF10 itself and its death receptor TNFRSF10B, along with cytokine production by microglia, reactive gliosis, and specific AD-related neuropathological hallmarks (i.e., Aβ deposition and Tau phosphorylation) in the retina of 3xTg-AD mice. In conclusion, immunoneutralization of TNFSF10 significantly preserved the retinal tissue in 3xTg-AD mice, suggesting its potential therapeutic application in retinal degenerative disorders.
Economic disparity among generations under the Paris Agreement
Authors: Yang Haozhe , Suh Sangwon 
Published: October 2021

AbstractThe costs and benefits of climate change mitigation are known to be distributed unevenly across time and space, while their intergenerational distribution across nations has not been evaluated. Here, we analyze the lifetime costs and benefits of climate change mitigation by age cohorts across countries under the Paris Agreement. Our results show that the age cohorts born prior to 1960 generally experience a net reduction in lifetime gross domestic product per capita. Age cohorts born after 1990 will gain net benefits from climate change mitigation in most lower income countries. However, no age cohorts enjoy net benefits regardless of the birth year in many higher income countries. Furthermore, the cost-benefit disparity among old and young age cohorts is expected to widen over time. Particularly, lower income countries are expected to have much larger cost-benefit disparity between the young and the old. Our findings highlight the challenges in building consensus for equitable climate policy among nations and generations.
High resolution global spatiotemporal assessment of rooftop solar photovoltaics potential for renewable electricity generation
Authors: Joshi Siddharth , Mittal Shivika , Holloway Paul , Shukla Priyadarshi Ramprasad , Ó Gallachóir Brian , Glynn James 
Published: October 2021

AbstractRooftop solar photovoltaics currently account for 40% of the global solar photovoltaics installed capacity and one-fourth of the total renewable capacity additions in 2018. Yet, only limited information is available on its global potential and associated costs at a high spatiotemporal resolution. Here, we present a high-resolution global assessment of rooftop solar photovoltaics potential using big data, machine learning and geospatial analysis. We analyse 130 million km2of global land surface area to demarcate 0.2 million km2of rooftop area, which together represent 27 PWh yr−1of electricity generation potential for costs between 40–280 $ MWh−1. Out of this, 10 PWh yr−1can be realised below 100 $ MWh−1. The global potential is predominantly spread between Asia (47%), North America (20%) and Europe (13%). The cost of attaining the potential is lowest in India (66 $ MWh−1) and China (68 $ MWh−1), with USA (238 $ MWh−1) and UK (251 $ MWh−1) representing some of the costliest countries.