bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diplegia nervi facialis paraesthesiával – ritka Guillain–Barré-szindróma-variáns, SARS-CoV-2-infekciót követően
Authors: Gaál Tibor , Szeszák Gergely , Torák Gyöngyi , Salacz Pál 
Published: December 2021

Összefoglaló. A COVID–19 világméretű járvány kapcsán már jól
ismertek az általános akut tünetek, mint a láz, a száraz köhögés, a nehézlégzés,
a tüdőgyulladás, a hasi panaszok, a hasmenés, az ízérzés- és szaglásvesztés.
Talán kevésbé ismertek a betegség neurológiai szövődményei: az encephalitis, a
fejfájás és szédülés, az ischaemiás stroke, az akut haemorrhagiás nekrotizáló
encephalopathia, de agitáltság és exekutív funkciózavar is kialakulhat. Hosszabb
távon az úgynevezett poszt-COVID-szindróma jelenhet meg, perzisztáló testi
panaszokkal, krónikusfáradtság-érzéssel, depresszióval, mentális problémákkal. A
perifériás idegrendszeri betegségek közül a Guillain–Barré-szindróma fordul elő
gyakrabban. Jelen közleményünkben egy diplegia nervi facialis, dysarthria és
négy végtagot érintő szubjektív paraesthesiák miatt hospitalizált 41 éves férfi
betegünk esetét ismertetjük, akinek felső légúti tünetekkel és lázzal járó
SARS-CoV-2-infekciót 10–14 nappal követően jelentek meg neurológiai tünetei.
Elektrofiziológiai és liquor laboratóriumi vizsgálat során alátámasztott módon,
ritka Guillain–Barré-szindróma-variáns – bifacialis paresis paraesthesiával –
igazolódott. Fontos, hogy a vírus idegrendszeri szövődményeit is ismerjük, mert
az esetszámok a jövőben várhatóan növekedni fognak. Orv Hetil. 2021; 162(45):
1803–1807.
Summary. After the worldwide spread of COVID-19, common symptoms are
already well known as fever, coughing, shortness of breath, pneumonia, abdominal
pain and diarrhea, either loss of olfaction or sense of taste. Neurological
complications are perhaps less known as headache, dizziness, agitation,
executive dysfunction or, in particular cases, viral encephalitis and acute
hemorrhagic necrotizing encephalitis may also occur. In COVID-19 patients,
ischemic stroke or cerebral vein thrombosis are also more commonly related to
the increased risk of thrombosis. In the long term, so called post-COVID
syndrome can emerge in the form of fatigue, depression or many other mental
disorders. The most common disease of the peripheral nervous system is
Guillain–Barré syndrome. This chapter reviews a case of a 41-year-old man
presented to the Department of Neurology with facial diplegia, dysarthria and
intermittent paresthesia of the upper and lower extremities. 10–14 days before
the onset of neurological symptoms, he has gone through COVID-19 infection that
involved fever and upper respiratory tract symptoms. Electrophysiology and
liquor samples showed typical signs of a rare Guillain–Barré syndrome subtype –
bifacial weakness with paresthesias. We are reviewing the neurological
complications of the virus due to the expected increase of case numbers. Orv
Hetil. 2021; 162(45): 1803–1807.
Pelayanan Administrasi Pertanahan Di Kecamatan Marpoyan Damai Kota Pekanbaru
Authors: Regita Alma Apriliya , Sadad Abdul 
Published: December 2021

The application of the Land Information System (SIPTANAH) in Marpoyan Damai District is a form of innovation from Mr. Fiora as the sub-district head in Marpoyan Damai District for the 2016-2019 term. This aims to facilitate urban villages that provide direct services to the community in land administration management services through SIPTANAH. This study aims to determine how the application of land administration management services through SIPTANAH in Marpoyan Damai District and the inhibiting factors of application that make land administration management through SIPTANAH no longer used in mid-2019. The theory used in this study is the theory of Taliziduhu Ndraha (2001: 67) which suggests that there are 4 (four) indicators in determining the quality of service, namely: Speed, Accuracy, Easiness, and Justice. This research uses qualitative research with a case study approach and the required data both primary and secondary are obtained from observation, interview and documentation techniques for further analysis using the interactive model of Miles and Huberman. The results of this study indicate that, the application of land administration services through SIPTANAH is quite optimal, but there are still several indicators that must be added, one of which is the human resources for operators who take care of land administration services through SIPTANAH at both the District and Kelurahan levels. And the inhibiting factors for the application of land administration services through SIPTANAH in Marpoyan Damai District are the lack of cooperation between the sub-district government and the village government, and outreach to the kelurahan.
Electric energy planning in Namibe, Angola: Inserting renewable energies in search of a sustainable energy mix
Authors: Lemba I. , Ferreira Dias M. , Robaina M. 
Published: December 2021

The socioeconomic development of any region requires electricity for operating the various sectors of the economy. Sometimes energy is scarce, not only because of the lack of energy resources, but also because energy policy is inadequate or non-existent. This paper examines the situation in the province of Namibe, Angola, characterising the energy sector, and proposing an energy mix for the security of electricity supply, environmental protection and sustainable economic development. Using the Long-range Energy Alternative and Planning System, energy scenarios were simulated and the greenhouse gas emissions (GHGs) for the period 2014-2040 calculated and analysed. The most sustainable scenario, in terms of energy mix diversification and GHG reduction, as well as the least costly (considering electricity production and carbon costs), has an increase of hydro capacity and the insertion of wind, solar photovoltaic, thermoelectric sources and natural gas. Given the intermittency of photovoltaic and wind systems, natural gas appears in this scenario as a way to avoid interruptions in the electricity supply. This scenario is the one with the largest production reserve margin of 24.47 %, and emissions are avoided at 386 550 tCO2eq compared to the base scenario in 2040. Energy policymakers can take this scenario as a model to assist in making decisions on how power capacities can be installed over the planned time for the desired energy output.
Gene polymorphisms associated with lipid metabolism disorders in young adults with risk of ­sudden cardiac death
Authors: Kachnov V A , Kryukov E V , Kolyubaeva S N , Kutelev G G , Tyrenko V V 
Published: December 2021

Aim. To study the frequency of polymorphisms in genes associated with lipid metabolism disorders in young people with risk of sudden cardiac death, to identify the relationships between gene polymorphisms and risk factors of sudden cardiac death, and to develop mathematical models to identify the probability of carrying mutations in these genes.
Methods. The study included 436 young people (mean age 19.81.6 years). A standard examination and survey by questionnaire specially developed by us were conducted to identify an increased risk of sudden cardiac death. 59 individuals with a risk of sudden cardiac death were selected. The control group was 65 people, which was comparable to the study group. A blood test was performed to determine lipid profile and polymorphisms: Leu28Pro (rs 429358) in gene APOE, C3238G (rs 5128) in gene APOC3, Gln192Arg (rs 662) in gene PON1, Ser447Ter (rs 328) in gene LPL, G250A (rs 1800588) in gene LIPC. Statistical analysis was performed using the statistical package SPSS 17.0 and Statistica 6.0. The parametric KruskalWallis test, the MannWhitney U-test, the Pearsons chi-squared test, the Spearman rank correlation coefficient, and logistic regression analysis were used.
Results. We revealed a high frequency of Gln192Arg (rs 662) polymorphism in the PON1 gene in the group of individuals at risk of sudden cardiac death and its correlation with the deaths in relatives under age 50 years. Mathematical models for predicting the presence of polymorphisms in genes associated with lipid metabolism disorders have been developed. Among the developed mathematical models, the models for identifying carriers of the minor allele of Gln192Arg polymorphism in the PON1 gene, Ser447Ter in the LPL gene, and 250 GA in the LIPC gene had the highest sensitivity, specificity, and accuracy.
Conclusion. In persons at risk for sudden cardiac death, it is advisable to conduct a screening for mutations in genes associated with lipid metabolism disorders, especially in Gln192Arg polymorphism in gene PON1.
Procedimiento para caracterizar analizadores de descargas parciales de HF, VHF y UHF utilizados para el diagóstico de las redes e instalaciones de alta tensión
Authors: Garnacho Fernando , Khamlichi Abderrahim , Rivera Jorge , Simón Pascual , Ramírez Ángel , Álvarez Fernando 
Published: December 2021

La monitorización y medida de las descargas parciales en las redes eléctricas e instalaciones de alta tensión para evaluar el estado del aislamiento de los activos es un tema de gran actualidad, sin embargo, no existen criterios ni procedimientos para evaluar las características técnicas de estos sistemas de medida y diagnóstico. Los sistemas de cable se monitorizan con sensores de tipo HFCT por tener alcances de medida de varios kilómetros cada sensor. En las instalaciones GIS, los sensores invasivos de tipo UHF son ampliamente utilizados, al presentar alta sensibilidad para detectar pequeñas DP pese a su corto su alcance de pocos metros y para los transformadores de potencia se utilizan las capacidades de las bornas capacitivas, como condensador de acoplamiento acoplado a una impedancia de medida. Aunque aparentemente no existe una solución universal para resolver el mismo problema “detección del defecto del aislamiento eléctrico”, en realidad no son bien conocidas las capacidades que tienen las diferentes técnicas de medida convencionales, en HF, VHF y las de UHF.
En este artículo se presenta un procedimiento de ensayo desarrollado con motivo del proyecto europeo “FuturEnergy” dentro del programa EURAMET que utiliza un banco de ensayo monofásico de alta tensión (20 kV) compuesto por una GIS y un sistema de cable que permite realizar pruebas de caracterización de sistemas de medida que utilicen sensores de tipo convencional, HFCT, VHF y de UHF. Las descargas parciales son generadas por un conjunto de probetas de referencia diseñadas al efecto o por un generador de trenes de pulsos de DP de referencia utilizado como calibrador.
Relacije Mračne tetrade, aleksitimije i distresa: analiza na nivou faceta, antagonističkog i agensnog faktora mračnih crta
Authors: Dinić Bojana M. , Cmiljanić Anđela , Rokvić Nikola 
Published: December 2021

Osnovni cilj ovog istraživanja je utvrđivanje relacija između crta Mračne tetrade i faktora aleksitimije, uzimajući u obzir multidimenzionalnu prirodu mračnih crta, kao i njihove antagonističke (maladaptivne) aspekte i aspekte delotvornosti ili agensne aspekte (adaptivnije aspekte). Dodatno, ispitana je medijatorska uloga faktora aleksitimije u odnosu između mračnih crta i distresa. Na uzorku od 355 ispitanika (71.3% ženskog pola) iz opšte populacije, primenjeni su sledeći instrumenti: Toronto skala aleksitimije, Skala depresije, anksioznosti i stresa, Levensonova skala psihopatije, Petofaktorski inventar makijavelizma, Kratka verzija Petofaktorskog inventara narcizma, Procena sadističke ličnosti. Rezultati pokazuju da mračne crte i faktori aleksitimije dele 56% zajedničke varijanse, te da su dominantni prediktori aleksitimije sekundarna psihopatija u pozitivnom smeru i makijavelistička delotvornost u negativnom smeru, a potom i narcistički antagonizam i primarna psihopatija, oba u pozitivnom smeru. Rezultati pokazuju da faktor mračnih crta koji okuplja agensne karakteristike na pozitivnom polu ostvaruje veći i negativni doprinos u objašnjenju aleksitimije i distresa, u odnosu na faktor koji okuplja primarno antagonističke karakteristike. Mračnim crtama je najviše objašnjen faktor aleksitimije koji se odnosi na probleme u identifikaciji emocija, i ujedno je ovaj faktor značajan medijator u predikciji distresa na osnovu sekundarne psihopatije, makijavelističke delotvornosti ili oba faktora mračnih crta. Naime, ovaj kognitivni deficit u razumevanju emocija doprinosi povećanju distresa u slučaju primarno antagonističkih mračnih crta, dok faktor delotvornosti preko manjih problema u identifikaciji emocija doprinosi redukciji distresa.
Genomic Responses Associated with Drought Stress in Walnut as Revealed Transcriptome Sequencing
Authors: Sadat-Hosseini Mohammad , Bakhtiarizade Mohammad Reza , Boroumand Naser , Tohidfar Masoud , Aliniaeifard Sasan , Vahdati Kourosh 
Published: December 2021

Abstract
Walnut production is challenged by abiotic stresses. We investigated the leaf transcriptome responses of walnut under control and drought stress in 9 and 18 days. We identified 921, 1035 differentially expressed genes (DEGs) between control and drought stress groups in 9 and 18-day, respectively. In control and drought stress conditions DEGs were significantly enriched into the abscisic acid biosynthesis, regulation of stomata closure, leaf morphogenesis, carbohydrate metabolism, oxidative stress, cell wall macromolecule catabolism, and secondary metabolite biosynthesis pathways. We confirmed our RNA-Seq data using quantitative real-time PCR (qPCR) of six candidate genes. Our results indicated that more complicated transcript regulation of drought responses following prolong exposure to drought stress. In general, walnut activated more tolerance mechanisms 18 days after drought stress. Findings of this research would be useful for future studies on breeding for drought tolerance of Persian walnut and related species.
Bilingual experiences induce dynamic structural changes to basal ganglia and the thalamus
Authors: Korenar Michal , Treffers-Daller Jeanine , Pliatsikas Christos 
Published: December 2021

Abstract
Bilingualism has been linked to structural adaptations of subcortical brain regions that are important nodes in controlling of multiple languages. However, research on the location and extent of these adaptations has yielded variable patterns. Existing literature on bilingualism-induced brain adaptations has so far largely overseen evidence from other domains that experience-based structural neuroplasticity often triggers non-linear adaptations which follow expansion-renormalisation trajectories. Here we use generalised additive mixed models (GAMMs) to investigate the non-linear effects of quantified bilingual experiences on the basal ganglia and thalamus in a sample of bilinguals with wide range of bilingual experiences. Our results revealed that volumes of bilateral caudate nuclei and accumbens were positively related to bilingual experiences in a non-linear pattern, with increases followed by decreases, in the most experienced bilinguals, suggesting a return to baseline volume at higher levels of bilingual experience. Moreover, volumes of putamen and thalamus were positively linearly predicted by bilingual experiences. The results offer the first direct evidence that bilingualism, similarly to other cognitively demanding skills, leads to dynamic subcortical structural adaptations which can be nonlinear, in line with expansion-renormalisation models of experience-dependent neuroplasticity.
Discovery of a conserved rule behind the assembly of β-barrel membrane proteins
Authors: Shiota Takuya , Germany Edward , Ding Yue , Imai Kenichiro , Bamert Rebecca , Dunstan Rhys , Nakajima Yukari , Lai Xiangfeng , Webb Chaille , Stubenrauch Christopher , Hidaka Kentaro , Thewasano Nakajohn , Tan Khershing , Shen Hsin-Hui , Lithgow Trevor 
Published: December 2021

Abstract
Gram-negative bacteria, mitochondria and chloroplasts contain β-barrel outer membrane proteins (OMPs). Most OMPs have a “β-signal” imprinted in the final β-strand. In Gram-negative bacteria, the β-barrel assembly machinery (BAM) complex recognize the β-signal for the folding and membrane insertion of the OMP. Here, we identified the “-5 signal”, a novel signal existing in the fifth β-strand from the C-terminus (-5 strand) responsible for the insertion step of the assembly process. We further identified the receptor for the -5 signal as BamD. BamD can recognize both β-signal and -5 signal, marshalling the OMP for assembly. There is sequence similarity in of both signals observed also in mitochondrial OMPs. Therefore, we propose the “-5 rule” repeating a similar sequence in the -5 and last strand, as a conserved feature of the OMP assembly process in bacteria and eukaryotes.
New Modification of Vertical Muscle Transposition to Enhance Abducting Force in Sixth Nerve Palsy
Authors: Heede Santa , Kovalevskaya Irina , Astle William , Valeina Sandra , Griebenow Uwe 
Published: December 2021

Abstract
Purpose:Since 1907, multiple transposition procedures have been established for the treatment of abducens paralysis. In this study, we try to determine where the transposed muscle should be reattached in order to increase the tangential force necessary to improve abduction.Methods:Retrospective case review of 12 consecutive patients with abducens paralysis. All patients underwent the transposition procedure between 2016 and 2019.Vertical rectus muscles are transposed to the insertion of lateral rectus muscle: The temporal parts are joined and sutured to the sclera on top of the lateral rectus muscle in the middle of the insertion. The nasal parts are sutured to the sclera following the spiral of Tillaux. The muscle junction suture is placed 8 mm from the insertion: The temporal parts of the vertical muscles bellies are joined and sutured to the lateral rectus muscle. A full tendon transposition was performed on 11 patients, a half tendon transposition procedure on one patient. The minimum follow-up was 3 months.Results:The mean preoperative deviation was ET of 37° (range: ET 24° to ET 51°). The mean preoperative abduction limitation was 5 mm from midline (range: -7 to -1mm). The postoperative mean deviation was ET of 2° PD (range: 0 to ET 5°). The postoperative mean abduction improvement was 5mm past midline (range: +2 to +6mm). There were no complications, or signs of anterior segment ischemia. Conclusions:To achieve the maximal abductive force from the transposed muscles, we suggest that the vertical muscles be reattached as close as possible to the middle of the lateral rectus insertion.
Cellulose/Exosome Nanocarrier for Improved Prolonged Release of 5-Fluorouracil: Preparation, Characterization, Drug Release Behavior and Cytotoxicity
Authors: Saeidifar Maryam , Seyedahmadi Mobina , Javadpour Jafar , Rezaei Hamid Reza 
Published: December 2021

Abstract
Designing of nanoparticle drug delivery systems and improving the efficacy of anticancer drugs are a great deal of effort in the recent years. In this study, a novel biocompatible nanocarrier based on bacterial cellulose (BC) in presence of exosome (Exo) was prepared to controlled release of 5-fluorouracil (5-FU), (5-FU.Exo@BC). The physicochemical properties of 5-FU.Exo@BC was characterized using field emission scanning electron microscopy (FESEM), Differential Scanning Calorimetry (DSC), Fourier-transform infrared spectroscopy (FTIR), and X-ray Diffraction (XRD) techniques that confirmed the successful preparation of 5-FU.Exo@BC. The release behavior of 5-FU.Exo@BC compared to 5-FU and 5-FU@BC demonstrated a significant sustained release during 162 h. The release mechanism of the above three systems followed Korsmeyer-peppas with non-Fickian diffusion for 5-FU@BC and 5-FU.Exo@BC. In addition, the viability of HT-29 cells (human colon cancer cell line), towards BC, 5-FU@BC and 5-FU.Exo@BC indicated the promising efficacy of 5-FU into 5-FU.Exo@BC. Subsequently, the prepared bio-nanocomposite could be proposed as a potential drug delivery system with effective controlled-release function.
Superabsorbent Polymer With Excellent Water/Salt Absorbency And Water Retention, And Fast Swelling Properties For Preventing Soil Water Evaporation
Authors: Tian Haizhou , Cheng Sha , Zhen Jianghong , Lei Ziqiang 
Published: December 2021

Abstract
Superabsorbent polymers have important applications in many fields, but insufficiency of water/salt absorbency, water retention, and swelling rate limit its application development. Herein, we fabricated HEC-g-P (AA-co-AMPS)/laterite by aqueous solution polymerization, the structure and morphology of the superabsorbent polymer were characterized by FTIR, SEM and TG/DTG. The optimal water absorbency of the superabsorbent polymer were 1294 g/g, 177 g/g, and 119 g/g in distilled water, tap water, and 0.9 wt% NaCl solution, respectively. The superabsorbent polymer had good water retention and re-swelling properties at different temperatures, and fast water absorption rate, and reached swelling equilibrium at 5 min. The swelling mechanism of the superabsorbent polymer was explained by the pseudo-second-order swelling kinetics model and Ritger-Peppas model. The effect of the amount of hydrogel on the water evaporation rate in soil was studied, and it had a good effect.
Whether Gastrorenal Shunt Embolization Would Benefit the Outcomes of Post Transjugular Intrahepatic Portosystemic Shunt
Authors: Zhao Dongmei , Wang Mingquan , Chen Guosheng , Zhang Guobing , Zhang Chaoxue , Li Jiabin 
Published: December 2021

Abstract
Background & Aim: Whether the spontaneous portosystemic shunts in cirrhosis who require embolization during transjugular intrahepatic portosystemic shunt (TIPS) remains a therapeutic controversial. This study was retrospectively conducted to evaluate the effectiveness of the gastrorenal shunts (GRS) embolization in cirrhosis post-TIPS。Methods: 70 cirrhotic patients who underwent TIPS in a tertiary-care center were included, of which 43 patients had no GRS and 27 had GRS with embolization during TIPS placement. Then, to assess the outcomes of embolization of GRS on post-TIPS hepatic encephalopathy (HE), clinical relapse, mortality and shunt dysfunction.Results: During a median follow-up period of 497.01 days, 25 patients (35.7%) experienced HE, of 14 patients in GRS group and 11 in another (p = 0.026). Within 50 days after TIPS, 12 patients performed initial HE in GRS group while 6 in the reference group (p < 0.001). After TIPS of 150th to 200th, one in the former group and five in another experienced HE (p < 0.001). However, there was no significant difference in the 1-year cumulative risk of HE (p = 0.287). Meanwhile, during the 2-year follow-up, the patients performed lower incidence of ascites after GRS embolization with TIPS (p < 0.002). And there was no difference in rebleeding, mortality and shunt dysfunction. Conclusions: TIPS with GRS embolization appeared to be a safe and efficacious procedure in the treatment of portal hypertension with concomitant GRS. Furthermore, the procedure seemed to reduce the recurrences of ascites for a long term observation.