bluuebunny/crossref_metadata_2025_split huggingface dataset:
Silver jar from the bosporan sanctuary of Demeter and Kore: results of neutron tomography and XRF investigations
Authors: Zavoikin Alexey , Saprykina Irina , Pelgunova Lubov , Kichanov Sergey , Kozlenko Denis 
Published: December 2021

This article presents the results of the study of a halide film formed on a surface of a silver jar found in 2002 in the sanctuary of Demeter and Kore on the Taman Peninsula (Krasnodar region, Russia). Investigated sanctuary is located within Beregovoy 4 settlement and was related to Eleusinian cults, which were already presented on the territory of the Cimmerian Bosporus. This silver jar was placed into a specially prepared ceramic hydriskos tightly closed with a sea herb rope. One side of the jar was covered by a crust of some substance. Firstly it was interpreted as sea salt remains, but in our case, this assumption can be excluded, because this place is located high above the sea level (12.60 m). The sanctuary is located at the foot of a mud volcano (Mount Gorelaya), its last eruption was occurred in 1794. It is known that the chemical composition of Taman volcanic muds is characterized by the presence of both Cl and Br. We assume that the presence of the halide film on the silver jar’s surface can be explained by peloids or volcanic mud, which had been used for medical practices or cultic rituals in the sanctuary of Demeter and Kore.
Regards croisés sur le sanctuaire laténien de La Peyrouse (Saint-Félix-de-Villadeix, Dordogne) : confrontation des données géophysiques et archéologiques
Authors: Hantrais Juliette , Mathé Vivien , Corfmat Pauline , Chevillot Christian , Chapoulie Rémy , Hiriart Eneko 
Published: December 2021

Le sanctuaire de La Peyrouse est situé sur la commune de Saint-Félix-de-Villadeix en Dordogne. Il a été découvert en 2019 lors d’une campagne extensive de prospection magnétique, réalisée sur un site d’habitat protohistorique et antique. De nouvelles prospections géophysiques ciblées, combinant méthodes magnétique et électrique, ont été menées dans le cadre d’une thèse intégrée au projet RAPSODIE (Reconnaissance des Agglomérations Protohistoriques du Sud-Ouest : Développement, Imagerie, Environnement). Les résultats obtenus ont permis de documenter davantage ce bâtiment, en livrant son plan et une première vision verticale des vestiges conservés grâce à une section électrique transversale. Il s’agit d’un enclos fossoyé quadrangulaire d’environ 25 m de côté, ouvert à l’est, délimitant un espace interne aménagé d’environ 700 m². En 2020, une fouille archéologique a complété cette approche non destructive en identifiant précisément la source des anomalies magnétiques et électriques. La confrontation des données géophysiques et archéologiques permet ainsi d’appréhender le premier sanctuaire attesté du territoire des Pétrocores, au cœur d’une agglomération ouverte du IIIe s. av. J.-C., un type d’habitat groupé précoce encore mal connu en Europe celtique.
Découverte d’une mare altomédiévale à Rivière-les-Fosses en Haute-Marne : l’Homme dans son environnement du ve au viie siècle
Authors: Pertuisot Gaëlle , Daoulas Geneviève , Doyen Élise , Lamy Valérie , Tegel Willy , Testard Pierre 
Published: December 2021

Une fouille préventive menée en 2017 sur une zone humide au « Vau du Guet » à Rivière-les-Fosses en Haute-Marne a été l’occasion de récolter, grâce à l’étude des écofacts conservés (pollen, macrorestes et bois), des données inédites sur le paysage d’un vallon entre le ve et le viie siècle de notre ère. L’impact de l’Homme sur son environnement a pu être observé avec le passage, au cours du haut Moyen Âge, d’un environnement boisé à un espace plus ouvert. Les données archéologiques acquises aux alentours de la mare permettent d’attribuer ces changements à des défrichements liés à l’implantation d’un habitat à proximité.
Service, expertise et archéométrie : état d’une réflexion collégiale
Authors: Balasse Marie , Bellot-Gurlet Ludovic , Dillmann Philippe , Geigl Eva-Maria , Jacob Jérémy , Lebon Matthieu , Le Hô Anne-Solenn , Lefèvre Jean-Claude , Leroyer Chantal , Mathé Vivien , Merle Valérie , Mirabaud Sigrid , Reiche Ina 
Published: December 2021

Suite à une journée thématique « Service et expertise par les sciences archéologiques et de la conservation » organisée par le réseau CAI-RN (Compétences Archéométriques Interdisciplinaires – Réseau National, MITI CNRS) les membres du Comité de Pilotage du réseau CAI-RN ayant participé à cette journée ont souhaité rassembler et clarifier dans ce texte un certain nombre des points évoqués lors des discussions. Ceci en donnant notamment une brève définition des termes « service » et « expertise » et en présentant les différents types de structures liées à la communauté archéométrique et réalisant ces activités. Cette proposition d’une première analyse de la situation actuelle propose aussi quelques pistes de réflexion.
La vie imaginaire d’Albucius selon Pascal Quignard, ou le destin rêvé de l’éloquence
Authors: Tlemsani-Cantin Jawad 
Published: December 2021

La vie imaginaire que Pascal Quignard consacre en 1990 à Albucius1, un orateur latin du ier siècle avant Jésus-Christ, a de quoi surprendre, mais elle ouvre paradoxalement bien des pistes pour qui s’intéresse à l’enseignement de l’éloquence à notre époque.Elle met d’abord en scène un représentant de l’éloquence judiciaire en action, un homme qui avait fréquenté les écoles de rhétorique et avait lui‑même eu des disciples. Cette vie, romancée, met aussi en valeur l’importance du désir, du corps, de la gêne même, et surtout de la fable dans un genre qu’on aurait tort de croire exclusivement argumentatif. Enfin, elle montre des orateurs qui, malgré leur exclusion de la vie politique par un empereur liberticide, ont réussi à donner encore plus de force à leurs discours.Dans une approche très contemporaine, Pascal Quignard réfléchit à de nouvelles formes génériques pour la fable et pour le discours, liant étroitement l’une et l’autre afin de voir naître une pensée neuve et de répondre à l’un des besoins fondamentaux de l’homo fabulator.
Tbet Expression by Regulatory T Cells Is Needed to Protect against Th1-Mediated Immunopathology during Toxoplasma Infection in Mice
Authors: Warunek Jordan , Jin Richard M , Blair Sarah J , Garis Matthew , Marzullo Brandon , Wohlfert Elizabeth A 
Published: December 2021

Abstract
Toxoplasma gondii infection has proven to be an ideal model to understand the delicate balance between protective immunity and immune-mediated pathology during infection. Lethal infection causes a collapse of T regulatory cells (Tregs) mediated by the loss of IL-2 and conversion of Tregs to IFN-γ–producing cells. Importantly, these Tregs highly express the Th1 transcription factor Tbet. To determine the role of Tbet in Tregs, we infected Tbx21f/f-Foxp3YFPCre and control Foxp3YFPCre mice with the type II strain of T. gondii, ME49. The majority of Tbx21f/f-Foxp3YFPCre mice succumbed to a nonlethal dose. Notably, parasite burden was reduced in Tbx21f/f-Foxp3YFPCre compared with Foxp3YFPCre control mice. We found that Tbx21f/f-Foxp3YFPCre mice have significantly higher serum levels of proinflammatory cytokines IFN-γ and TNF-α, suggestive of a heightened immune response. To test if CD4+ T cells were driving immunopathology, we treated Tbx21f/f-Foxp3YFPCre mice with anti-CD4–depleting Abs and partially rescued these mice. Broad-spectrum antibiotic treatment also improved survival, demonstrating a role for commensal flora in immunopathology in Tbx21f/f-Foxp3YFPCre mice. RNA sequencing analysis reinforced that Tbet regulates several key cellular pathways, including leukocyte activation, regulation of lymphocyte activation, and cell cycle progression, that help to maintain fitness in Tregs during Th1 responses. Taken together, our data show an important role for Tbet in Tregs in preventing lethal immunopathology during T. gondii infection, further highlighting the protective role of Treg plasticity in controlling immune responses to infection and the microbiota.
ABCB10 Loss Reduces CD4+ T Cell Activation and Memory Formation
Authors: Sun Wenxiang , Jia Xuan , Liesa Marc , Tantin Dean , Ward Diane M 
Published: December 2021

Abstract
T cells must shift their metabolism to respond to infections and tumors and to undergo memory formation. The ATP-binding cassette transporter ABCB10 localizes to the mitochondrial inner membrane, where it is thought to export a substrate important in heme biosynthesis and metabolism, but its role in T cell development and activation is unknown. In this article, we use a combination of methods to study the effect of ABCB10 loss in primary and malignantly transformed T cells. Although Abcb10 is dispensable for development of both CD4+ and CD8+ T cells, it is required for expression of specific cytokines in CD4+, but not CD8+, T cells activated in vitro. These defects in cytokine expression are magnified on repeated stimulation. In vivo, CD8+ cells lacking ABCB10 expand more in response to viral infection than their control counterparts, while CD4+ cells show reductions in both number and percentage. CD4+ cells lacking ABCB10 show impairment in Ag-specific memory formation and recall responses that become more severe with time. In malignant human CD4+ Jurkat T cells, we find that CRISPR-mediated ABCB10 disruption recapitulates the same cytokine expression defects upon activation as observed in primary mouse T cells. Mechanistically, ABCB10 deletion in Jurkat T cells disrupts the ability to switch to aerobic glycolysis upon activation. Cumulatively, these results show that ABCB10 is selectively required for specific cytokine responses and memory formation in CD4+ T cells, suggesting that targeting this molecule could be used to mitigate aberrant T cell activation.
Frequency and Correlates of Hypogonadism in Adult Males with Type 2 Diabetes Mellitus
Authors: Gangwar Saurabh K. , Verma Sanjiv K. , Modi Sagar 
Published: December 2021

Background and Aims:There is increasing awareness about an association between type 2 diabetes mellitus (T2DM) and male hypogonadism. However, data are sparse and less uniform with respect to factors associated with hypogonadism in males with T2DM. This study aimed to assess the frequency and correlates of hypogonadism in these subjects.Materials and Methods:This cross-sectional study included 130 males with T2DM, age 25-60 years. Study subjects were screened for hypogonadal symptoms using androgen deficiency in aging male (ADAM) questionnaire. Serum total testosterone was measured in subjects with positive ADAM score. Hypogonadism was defined as the presence of positive ADAM score and low serum total testosterone (<3 ng/mL). Clinical and biochemical variables were compared between T2DM subjects with and without hypogonadism.Results:Hypogonadism was observed in 26.9% of the study subjects. Hypogonadal symptoms most frequently observed in patients with T2DM and hypogonadism were erectile dysfunction (96.4%), reduced libido (64.3%) and deterioration in work performance (53.6%). Group with T2DM and hypogonadism had higher (i) duration of T2DM (8.9 ± 5.03 vs. 4.8 ± 4.76 years;P= .001), (ii) frequency of diabetic retinopathy (58.3% vs. 27.3%;P= .008), (iii) frequency of diabetic neuropathy (42.9% vs. 19.7%;P= .024), (iv) proportion of subjects on insulin therapy (46.4% vs. 22.4%;P= .027), and (v) HbA1c (10.9 ± 2.63% vs. 9.3 ± 2.42%;P= .006), compared to group without hypogonadism.Conclusion:Hypogonadism was present in nearly one-fourth of the study subjects with T2DM. Compared to the subjects without hypogonadism, group with hypogonadism had longer duration of diabetes, higher HbA1c, greater frequencies of diabetic retinopathy and diabetic neuropathy, and more subjects on insulin therapy.
Invariants for metabelian groups of prime power exponent, colorings, and stairs
Authors: Barmak Jonathan Ariel 
Published: December 2021

AbstractWe study the free metabelian group
$M(2,n)$
of prime power exponent n on two generators by means of invariants
$M(2,n)'\to \mathbb {Z}_n$
that we construct from colorings of the squares in the integer grid
$\mathbb {R} \times \mathbb {Z} \cup \mathbb {Z} \times \mathbb {R}$
. In particular, we improve bounds found by Newman for the order of
$M(2,2^k)$
. We study identities in
$M(2,n)$
, which give information about identities in the Burnside group
$B(2,n)$
and the restricted Burnside group
$R(2,n)$
.
The Role of Self Esteem in Developing Social Anxiety
Authors: Calin Mariana Floricica , Sandu Mihaela Luminita , Chifoi Miruna Alexandra 
Published: December 2021

Nowadays, anxiety is a growing phenomenon because people come across more and more stressful situations. Therefore, among its different forms of manifestation, there is social anxiety. This type of anxiety generally starts in adolescence, when personality is still shaping up and when teenagers are more and more interested in getting confirmation from others. When he is analyzed by others, a teenager fears failure and being ashamed when things are not the way they should, he fears being judged by others for possible small mistakes and, thus, anxiety appears. In other words, persons with low self-confidence and lacking confidence in their abilities have low self-esteem and can easily develop a form of anxiety. As we have already mentioned, social anxiety is caused by the fear of being criticized by others, by the fear of being improperly evaluated, by the feeling of being ashamed, of being in the presence of unknown persons, etc. All these social contexts are backgrounds for individuals’ unexplainable restlessness that can lead to physical symptoms such as excessive perspiration, trembling, palpitations, blushing etc. Self-esteem is very important here as it is very important how the subject sees himself or herself in the social situation. Thus, if a person feels unable to deal with situations considered difficult and if there is lack of confidence in her/his own abilities, meaning he/she has low self-esteem, it is highly possible that this behaviour lead to the debut of social anxiety. Therapy sessions help reduce and even eliminate this disturbance. There are certain techniques consisting of facing the problems up to the moment where the subject begins feeling comfortable with normal life aspects which used to be considered anxiety episodes.
BRIDGING ECONOMIC INEQUALITY GAP IN DEVELOPING COUNTRIES: A DIAGNOSIS OF OBSTACLES AND OPPORTUNITIES IN THE CONTEXT OF UGANDA
Authors: Clief Naku Daniel Wandera 
Published: December 2021

Purpose: Economists argue that a nation will never survive morally or economically when so few have so much, while so many have so little. In the context of Uganda where the level of economic inequality is high as revealed by the present gini coefficient of 0.42, the purpose of this paper was to explore obstacles making it difficult to bridge economic inequality in the country and the possible opportunities that could be capitalized on so as to bridge this gap.
Methodology: The study employed an extended literature review to explore the state of economic inequality in Uganda, the obstacles to dealing with the problem of economic inequality and the possible opportunities for addressing economic inequality in Uganda
Findings: Study findings show that economic inequality in Uganda is a chronically growing problem that will need more than just policies and regulations to deal with it. In this regard, political will and commitment by both the government of Uganda and its citizens are essential factors in this struggle.
Unique contribution to theory, practice and policy: The paper recommends that the political will and commitment of the prevailing leadership and policy makers in Uganda will be vital in bridging economic inequality gap in the country.
IDENTIFICATION AND PREVENTION OF EXPECTED CYBERSECURITY THREATS DURING 2022 FIFA WORLD CUP IN QATAR
Authors: Khalifa Nasser AL-Dosari 
Published: December 2021

Purpose: This research aimed to identify cybersecurity threats expected at the upcoming FIFA World Cup in Qatar in 2022 and assess how they can be prevented.
Methodology: This was done by adopting a quantitative research design and survey strategy with 167 respondents from Qatar. The respondents were purposively sampled from the event industry, and a Likert scale was used to quantify the responses for further statistical analysis. The quantitative data collected was analysed using the SPSS version 25 for data analysis. A hypothesis was tested as to whether the perceived expected cybersecurity threats are significantly associated with the perceived quality of measures to tackle these threats. The testing was done using multiple methods, including Principal Component Analysis (PCA) and cross-sectional linear regression analysis. Further analysis was done using One-way ANOVA and correlation analysis, as well as, independent samples t-test. Descriptive statistics, such as percentages and frequencies were used, with tables and charts used in presenting the findings.
Findings: The results revealed high loadings of potential cyberattacks on sponsors, fans, online ticket sales, government and the FIFA website based on the PCA. The regression analysis revealed a statistically significant association between the perception of the cybersecurity risks and perceived quality of measures undertaken to address the cyber threats. The research was limited, however, by not covering technical issues of cybersecurity, including the development of improvements to current security systems, which presents an area for future research with the implementation of machine learning technologies, big data and AI training.
Contribution: The study provided recommendations for policymakers to invest in technologies for the protection of sensitive data, including online databases and hiring competent specialists in the field of cybersecurity. To address the risks for fans, policymakers are recommended to start a campaign aimed at increasing the awareness of cyberattacks on personal and financial information at large events.
The profile of the COvid-19 VACcination register SAFEty study in Sweden (CoVacSafe-SE)
Authors: Ljung Rickard , Sundström Anders , Grünewald Maria , Backman Charlotte , Feltelius Nils , Gedeborg Rolf , Zethelius Björn 
Published: December 2021

Background: The coronavirus disease 2019 (COVID-19) vaccines have been rapidly implemented in national vaccination programs world-wide after accelerated approval processes. The large population exposure achieved in very short time requires systematic monitoring of safety. The Swedish Medical Products Agency has launched a project platform for epidemiological surveillance to detect and characterise suspected adverse effects of COVID-19 vaccines in Sweden.
Methods: The platform includes all individuals 12 years or older in Sweden in 2021 and will be updated annually. Data, including vaccine and COVID-19 disease data, socioeconomic and demographic data, comorbidity, prescribed medicines and healthcare utilisation outcomes, are obtained from several national registers in collaboration with other Swedish Government agencies. Data from 2015 to 2019 are used as a historical comparison cohort unexposed to both the COVID-19 pandemic and to the COVID-19 vaccines.
Results: The primary study cohort includes 8,305,978 adults 18 years and older permanently residing in Sweden on 31 December 2020. The historical control cohort includes 8,679,641 subjects. By 31 July 2021, around 50% of those 18 years and older and two-thirds of those 50 years and older were vaccinated with at least one dose, 90% of those 70 years or older had two doses.
Conclusions: The nationwide register-based study cohort created by the Swedish Medical Products Agency with regular updates of individual level linkage of COVID-19 vaccination exposure data to other health data registers will facilitate both safety signal detection and evaluation and other pharmacoepidemiological studies.
SISTEM INFORMASI ABSENSI DAN PENGGAJIAN DENGAN MEMANFAATKAN RFID READER (STUDI KASUS : PT. USAHA MANDIRI EKSPORTAMA)
Authors: Rusito Rusito , Rurin Masnunah  
Published: December 2021

Information technology is not only expected to be a supporting device and facilitate the company's operational activities, but has become part of the strategy in maintaining employee performance. PT. Usaha Mandiri Exporttama is a company engaged in assembling and manufacturing gas stoves for export destinations with a total of ± 150 employees. Having problems in terms of: (1) Efficiency, (2) Data Accuracy, (3) Timeliness, (4) Data Search, (5) Data Calculation. Seeing the weaknesses in the company, researchers designed a web-based attendance and payroll information system using the PHP programming language and MySQL database. The Rfid Reader and Card/Tag

tools were selected to facilitate employee attendance in large numbers. The Information System will immediately record as soon as the card is attached to the Rfid Reader. In this study, researchers used the research method of the Borg and Gall (1987) model from 10 steps to 6 steps. The test results related to the design show the final value of the calculation is 3.0, then the system is declared valid. The validation test by system experts related to usage shows the final value of the calculation is 2.9, concluding that the system is very feasible to use. User Validation at PT. Usaha Mandiri Exporttama Semarang obtained the final value of the calculation is 3.5 stating that the system is feasible to use and very good. The performance test by 4 respondents of the old system and the new system with an average of 43.7% of the old work system, and 87.5% of the new work system showed that the new system was effective and efficient.
PEMANFAATAN METODE ACTIVITY BASED COSTING DALAM SISTEM INFORMASI AKUNTANSI PENENTUAN BIAYA PADA BENGKEL MUJI JAYA
Authors: Sukemi Kamto Sudibyo  , Fitri Puji Astuti  
Published: December 2021

The Muji Jaya Workshop in determining the cost of body repair, it still uses a manual estimate model with paper media which will result in losses if the calculation of the cost of body repair that is informed to the customer is not enough so that the body repair costs received are not sufficient for the needs of raw material costs and labor costs in body work. The repair and preparation of financial statements will be disrupted and delayed for a long time if the note paper used is lost or damaged. This results in the owner not being able to make decisions quickly, precisely and accurately.
From these various problems, Workshop Muji Jaya implements the use of the activity based costing method in the accounting information system for determining body repair costs in order to make it easier to determine the cost of body repairs to be more accurate and in presenting financial statements to be easier and more efficient because this method is guided by the assignment of costs to products. or services based on all required activities.

Keywords: estimation, cost, activity based costing
Model of the functioning of the active security system of a social network user account
Authors: Черкасов Александр Николаевич , Сивенко Алена Валерьевна 
Published: December 2021

Проведен анализ развития нейросетевых алгоритмов в социальных сетях. Представлен алгоритм функционирования системы обеспечения активной безопасности учетной записи пользователя. Разработано программное обеспечение, позволяющее оценить надежность и предложить рекомендации по защите учетной записи пользователя в социальной сети « ВКонтакте » .
The analysis of the development of neural network algorithms in social networks is carried out. The algorithm of functioning of the system for ensuring the active security of the user account is presented. The software has been developed to assess the reliability and propose recommendations for protecting a user's account on the « ВКонтакте » (“In Contact”) social network.