bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improving Family Health Climate, Effect of Role Modeling and Maternal Support in Female Student
Authors: Ostovarfar Jeyran , Kaveh Mohammad Hossein , Ghahramani Leila , Karimi Masoud , Asadollahi Abdolrahim , Zare Razie 
Published: December 2021

Abstract
Introduction: Girls can use their mothers emotional, informational and behavioral support to perform healthy behaviors due to their constant access to their mothers. This study aimed to evaluate the effect of role modeling and maternal support in the family to improve healthy behaviors and perceived Family Health Climate (FHC) in female students.Methods: In this quasi-experimental study 261 female students (133 in intervention group and 128 in control group) and 223 mothers (109 intervention and 114 control) were selected, using cluster multi-stages sampling method and entered the study. Participants completed the FHC scale at three stages (Before intervention, immediately after the intervention and two month after intervention). A training programme which comprised 12 sessions for students and 6 sessions for their mothers using collaborative learning techniques and printed materials was conducted with the experimental group. Data were analyzed using SPSS20 via chi-square test, independent t-test, and Repeated Measures ANOVA at significance level of 0.05.Results: Before the intervention, there was no significant difference between demographic variables and the score of FHC scale in both groups (p<0.05). Immediately and two months after the intervention, the experimental group (female students and their mothers) showed a significant increase in dimensions of FHC including FHC-NU and FHC-PA (their subscales) compared to the control group (p<0.05).Conclusions: Educating and informing mothers about their role model defects for their children, especially girls, can make them more aware of health-oriented behaviors towards their children. Such findings reinforced the importance of focusing on actions to encourage a healthy lifestyle (healthy diet and physical activity) in students with a focus on role modeling and parental support, especially mothers.
Determinants of Pelvic Organ Prolapse at Public Hospitals in Hawassa City, Southern Ethiopia, 2020: Unmatched Case Control Study
Authors: Dora Bezabih Terefe , Kassa Zemenu Yohannes , Hadra Nebiha , Tsigie Bamlaku Birie , Esayas Hawi Leul 
Published: December 2021

Abstract
Introduction: Even though the Pelvic organ prolapse (POP) is outstanding gynecologic problem, most private and asymptomatic nature of the illness makes it the “hidden epidemic.” The aim of this study was to identify the determinants of POP. Methods: Facility based unmatched case control study was conducted from June 15 to September 10, 2020. All cases diagnosed with POP were enrolled in the study by using consecutive random sampling method by assuming that patient flow by itself is random until the required sample size was obtained. Then 1:2 cases to control ratio was applied. A structured interviewer-administered questionnaire and chart review for type and degree of prolapse was used. Epi-data and SPSS were used for analysis. Chi square test and binary and multivariable logistic regression analysis was employed. Multicolinearity was checked. Result: On multivariate logistic regression, heavy usual work load(AOR=2.3, CI(1.066-4.951), number of pregnancy ≥ 5(AOR=3.911, CI(1.108-13.802), birth space of <2 years(AOR=2.88, CI(1.146-7.232), history of fundal pressure (AOR=5.312, CI(2.366-11.927) and history of induced labor (AOR=4.436, CI(2.07-9.505) were significantly associated with POP with P value <0.05 and 95% CI after adjusting for potential confounders.Conclusion: Heavy usual work load, having pregnancy greater than five, short birth space, history of induced labor, and history of fundal pressure are independent predictors of pelvic organ prolapse. Hence the responsible body and obstetric care providers should counsel the women about child spacing. The obstetric care providers also avoid fundal pressure and the hospital officials set a law to ban fundal pressure during labor.
Photocatalytic Remediation of Methylene Blue and Antibacterial Activity Study Using Schiff Base - Cu Complexes
Authors: H Fathima Fasna P , Sasi Sreesha , K Bindu Sharmila T , S Julie Chandra C , Antony Jolly V , Raman Vidya 
Published: December 2021

Abstract
Photocatalytic degradation of organic dyes under visible light and ultraviolet radiation is an efficient strategy for effluent treatment. This work describes the design of novel Cu(II) complexes using the ligand N'-(3-hydroxy-4-methoxybenzylidene)nicotinohydrazide and their application in the photocatalytic degradation of the organic dye, methylene blue (MB). The photocatalytic degradation of MB follows pseudo first-order kinetics with high correlation coefficient values (R2> 0.95), making them useful as simple and low-cost organic dye degradation agents. The antibacterial screening studies of the ligand and the Cu(II) complexes by disc diffusion method show the systems to exhibit activity against Escherichia coli (gram negative) and Bacillus circulans (gram positive).
Anaerobic Co-Digestion of Food Waste and Thermal Pretreated Waste Activated Sludge: Synergetic Effect and Energy Assessment
Authors: Zhang Jian , Gan Peng , Wang Ru-yi , Xie Tian , Liu Yang , Zong Yi-feng , Wei Yan-ling 
Published: December 2021

Abstract
Thermal pretreatment was an effective method to improve the anaerobic digestion of waste activated sludge. However its application in China was still hindered by the high energy demand. In order to balance the energy consumption of sludge thermal pretreatment integrated with anaerobic digestion, food waste was introduced as co-substrate to achieve an energy self-sustainable sludge treatment system. Anaerobic biodegradability test was performed using thermal pretreated sludge and food waste in order to clarify the kinetics and mechanism of co-digestion, especially the synergetic effect on specific methane yield. The prominent synergetic effect was an initial acceleration of cumulative methane production by 20.7- 23.8% observed during the first 15 days, and the cumulative methane production of feedstock can be calculated proportionately from its composition. Between the evaluated models, modified Gompertz model presented a better agreement of the experimental results and it was able to describe the synergetic effect, assessed by the relative deviation between theoretical estimation and the experimental results of co-digestion tests. This feature made modified Gompertz model a suitable tool for methane production prediction of mono- and co-digestion. Energy assessment shown that co-digestion with food waste was a sustainable solution to maintain the integration of thermal pretreatment and anaerobic digestion energy neutral or even positive. Besides, the performance of sludge dewatering was a crucial factor for the energy balance.
Factors Associated with a Malaria Outbreak at Tongogara Refugee Camp in Chipinge District, Zimbabwe, 2021: A Case-Control Study
Authors: Takarinda Kudzai Patience , Nyadundu Simon , Govha Emmanuel , Chadambuka Addmore , Gombe Notion Tafara , Juru Tsitsi Patience , Tshimanga Mufuta 
Published: December 2021

Abstract
Background: Malaria is a leading cause of morbidity and mortality among forcibly displaced populations including refugees, approximately two-thirds of whom reside in malaria endemic regions. Data from the rapid disease notification system (RDNS) reports for Manicaland Province in Zimbabwe showed that despite implementation of malaria control initiatives, there was an increase in number of malaria cases above action thresholds at Tongogara Refugee Camp in Chipinge District during weeks 12-14. We investigated the malaria outbreak describing the outbreak by person, place and time, assessing malaria emergency preparedness and response and appropriateness of case management. We also determined the factors associated with contracting malaria to enable the formulation of appropriate interventions, establish control and prevent future malaria outbreaks among this vulnerable population.Methods: We conducted a 1:1 unmatched case control study involving 80 cases and 80 controls using interviewer-administered questionnaires at household level. Data was entered using Epi Data version 3.1 and analyzed using Epi InfoTM version 7.2.4 to generate medians, proportions, odds ratios and their 95% confidence intervals.Results: Malaria cases were distributed throughout the 10 residential sections within Tongogara Refugee Camp, the majority being from section 7, 28/80 (35%). Despite constituting 11% of the total population, Mozambican nationals accounted for 36/80 (45%) cases. Males constituted 47/80 (59%) among cases versus controls 43/80 (54%), p=0.524. Median age for cases was also lower compared to controls; 15 years [Interquartile range (IQR), 9-26] versus 17 years (IQR, 10-30). Several natural and manmade potential vector breeding sites were observed around the camp. Risk factors associated with contracting malaria were engaging in outdoor activities at night [AOR 4.26 (95% CI, 1.43-12.68)], wearing clothes that do not cover the whole body [AOR=2.74 (95% CI 1.04-7.22) while sleeping in a refugee housing unit reduced the risk of contracting malaria [AOR=0.18 (CI, 0.06-0.55)]. Conclusions: The malaria outbreak at Tongogara Refugee Camp reemphasizes the role of behavioral factors in malaria transmission. We recommend intensified health education to address human behaviors that expose residents to malaria and habitat modification with larviciding to eliminate mosquito breeding sites.
Photonic Remote Microwave Frequency Measurement With a Tunable Measurement Range Based on Dispersion Compensation Technology
Authors: Meng Qingqing , Zhu Zihang , Lin Tao , Li He , Wang Guodong , Huang Lanfeng , Li Xuan , Yu Longqiang , Zhao Shanghong 
Published: December 2021

Abstract
In this paper, a novel and efficient photonic-assisted remote frequency measurement (RFM) system with a significantly simplified structure and flexible operation range is proposed. By simply changing the dispersion coefficient or length of the dispersion medium in the central station (CS), the microwave frequency measurement range in the remote antenna unit (RAU) can be tuned. In this system, the RAU and the CS is separated to ensure the concealment and safety of the signal processing unit. The measurement range of the RFM system can be tuned easily during the measurement process without system reconstruction, and different RAUs located at different places can be controlled to work at the same measurement range. The simulation results show that a frequency measurement over the high frequency range (>18 GHz) can be achieved with a measurement error better than ±0.2 GHz. Noteworthy, the impact of the non-ideal factors such as bias drift, intensity noise, phase noise, the equivalent deviation of the polarization beam splitter (PBS), and the dispersion value of the single mode fiber (SMF) is also discussed. It has been proved that they have little influence on the system performance over the high frequency range.
Utility of Cell-Free DNA from Bronchoalveolar Lavage Fluids Using Next Generation Sequencing in Predicting Malignant Solitary Pulmonary Nodules
Authors: Qi Jia-Chao , Lin Li , Zhao Zhiwei , Liao Liping , Lin Yixuan , Wang Tiezhu , Hu Miaofen , Wu Zhi , Ou Yangwu , Cai Zhiming , Ye Yuming , Wu Qiyin , Xu Qiaozhen , Zhang Weiliang , Huang Wensen , Li Hao 
Published: December 2021

Abstract
Purpose: To explore the utility of cell-free DNA (cfDNA) from bronchoalveolar lavage fluids (BALF) using next generation sequencing (NGS) in differentiating malignant tumors from benign solitary pulmonary nodule (SPN).Methods: Between January 1st 2019 and January 1st 2021, 40 subjects undergoing computed tomography (CT) examination who were diagnosed with SPN, were prospectively enrolled at Zhangzhou Affiliated Hospital of Fujian Medical University (Zhangzhou, Fujian, China). And pathological diagnosis were finally confirmed from tissue specimens obtained by surgical resection. For each patient, the mutations of gene were analysed using NGS in both extraction of cfDNA isolated from BALF and tissue. Results: Of 40 patients, 55% of them were diagnosed with lung adenocarcinoma, 20% with benign nodules, and 10% with small cell carcinoma. And patients with squamous carcinoma, adenosquamous carcinoma or large cell neuroendocrine carcinoma account for 5%, respectively. And 62.5% of malignant SPN (10/16) had at least one alteration. The most common alterations were TP53 (31.25%), followed by EGFR (18.75%), KRAS (12.5%), PIK3CA (6.25%), ERBB2 (6.25%), ALK (6.25%) and ROS1 (6.25%). Besides, there are some differences shown in the heatmap of gene mutation in the histologic sample. And there was a colse correlation between the mutations found in the tissue and BALF. For all 40 patients, the sensitivity, specificity, and concordance of BALF in predicting malignant nodules were 68.8%, 100%, and 75%, respectively. Conclusions: By NGS, tumor-specific mutations of cfDNA from BALF may be benefical to predicting malignant SPN, which may be taken into consideration for personalized cancer diagnosis.
A Discussion on Sea Level Rise, Rate Ad Acceleration. Venice as a Case Study
Authors: Camuffo Dario 
Published: December 2021

Abstract
The paper discusses the equations used to represent the sea level rise, and in particular the second-order polynomial, generally preferred because its second-order coefficient is related to acceleration. The long series of the sea level rise in Venice offers a particularly useful case study from 1350 to 2016, because it may be equally represented, at the same level of explained variance, by an exponential or a quadratic best-fit equation. The first-order and the second-order derivatives respectively represent the rate and the acceleration of sea level rise. The derivatives obtained from the second-order polynomial representation generate a linear rate and a constant acceleration, while those derived from an exponential preserve the exponential character. The two rates (i.e. from the quadratic and the exponential equations), and the two accelerations are characterized by different equations and different plots, but their average values are the same. The second-order polynomial with constant acceleration is in line with a climate with constant forcing factors; the exponential with a dynamic condition with increasing forcing factors and acceleration. Mathematical formulae and physical consequences are discussed in the framework of different scenarios. Finally, the trend-forecast extrapolation is discussed and applied to the case study of Venice. It is shown that, in the most optimistic assumption of forcing increasing at unchanged rate, the sea level in Venice will rise by 33.8 ± 4 cm over this century, that may be compared to the 31 cm of the similar, most optimistic prediction made by IPCC for business-as-usual.
16S rRNA Gene Sequencing Reveals Altered Composition of Gut Microbiota in Postoperative Individuals With Renal Stones
Authors: Deng Qiong , Wang Zhu , Wang Jieyan , Zhang Jianwen , Zhang Ying , Zhang Lirong , Liang Hui 
Published: December 2021

Abstract
BackgroundRenal stones are a common urological disease with high prevalence and recurrence rates. Characterizing gut microbiome profiles of first-onset renal calculi patients, both before and after surgery, may provide valuable insights and identify potential biomarkers for the disease. MethodsWe explored the associations between the gut microbiome and renal stone formation using 16S ribosomal RNA (rRNA) gene sequencing. In brief, 20 patients were recruited, and information on health and eating habits within the previous 1-3 months was collected upon admission.ResultsA total of 493 OTUs were detected in 40 specimens, with an average of 67,888 ± 827 reads per sample. The results of OUT-based PLS-DA analysis showed significant differences between RS1 and RS2 groups, with a significantly higher level of OTU7 in the RS2 group. Taxonomy‑based comparisons of the gut microbiome showed differences in the flora composition, with the prevalence of Enterobacteriales, Enterobacteriaceae, Gammaproteobacteria, and Escherichia being higher in the RS2 group and the prevalence of Pseudomonadaceae, Pseudomonadales, and Pseudomonas being higher in the RS1 group.ConclusionsThese data strongly suggest that the gut microbiome affects kidney stone formation, and these findings may provide new insights for the prevention, diagnosis, and treatment of renal stones.
Dynamic Responses of Multidiameter-class Fine Roots at Different Soil Depths to Thinning Measures in a Secondary Forest in China
Authors: Pang Yue , Tian Jing , Wang Dexiang 
Published: December 2021

Abstract
Background: Fine roots make critical contributions to carbon stocks and terrestrial productivity, and multidiameter-class fine roots exhibit functional heterogeneity. However, the dynamic characteristics of multidiameter-class fine roots at different soil depths following thinning disturbances are poorly understood. We investigated the biomass, production, mortality and turnover rate of < 0.5 mm, 0.5–1 mm and 1–2 mm fine roots at 0-20 cm, 20-40 cm and 40-60 cm soil depths under five thinning intensities (0%, 15%, 30%, 45%, and 60%) in a secondary forest in the Qinling Mountains. Results: The biomass, production and turnover rate of < 0.5 mm fine roots fluctuated with increasing thinning intensity, while 0.5-1 mm and 1-2 mm fine root biomass significantly decreased. Thinning measures had no effects on fine root necromass (except for T4) or mortality. The fine root dynamic characteristics in deeper soils were more sensitive to thinning measures. Principal component analysis results show that increased < 0.5 mm fine root biomass and production resulted from increased shrub and herb diversity and biomass and decreased soil nutrient availability, stand volume and litter biomass, whereas 0.5-1 mm and 1-2 mm fine root biomass showed the opposite trends and change mechanisms. Conclusions: Our results provide evidence of the positive effect of thinning on very fine root (< 0.5 mm) biomass and production and the negative effect on thicker fine roots (0.5-1, 1-2 mm) or all fine root (< 2 mm) biomass. From the perspective of fine root biomass and productivity, T2 (30%) is recommended for use in secondary forests of the Qinling Mountains. Moreover, our results suggest that thinning practices have varied effects on the dynamic characteristics of multidiameter-class fine roots.
The Differences of the Acromiohumeral Interval Between Supine and Upright Radiographs of the Shoulder
Authors: Sanguanjit Prakasit , Apivatgaroon Adinun , Boonsun Phanuwat , Srimongkolpi Surasak , C้hernchujit Bancha 
Published: December 2021

Abstract
Background: Acromiohumeral interval (AHI) is a measurement method to determine the superior migration of the humeral head in patients with rotator cuff tears.Hypothesis/Purpose: The purpose of this study was to compare the AHI measurement in supine shoulder and upright shoulder radiographs, as well as magnetic resonance imaging (MRI), as well as to report the sensitivity, specificity, and accuracy in detecting full thickness rotator cuff tears.Study Design: Diagnostic study.Methods: From July 2020 to May 2021, evaluation of 86 shoulder radiographs in both supine & upright Grashey views compared with the MRI of the affected shoulder. Measurements of the AHI obtained from both radiographs and MRIs was determined by two independent orthopaedic surgeons. The intraclass correlation of the AHI measurement was tested. The difference between the AHI in each view was determined.Result: The 86 shoulders were divided into 3 groups that included; 1) non-full thickness tear (50%), 2) full thickness (FT) tear 3 cm (33.7%), and 3) FT tear > 3 cm (16.3%). The mean difference of AHI noted was significantly lower in the supine radiographs than with the upright (1.34-1.37 mm.). The mean difference of the AHI was significantly lower in the MRI than the upright (1.62-1.87 mm.). AHI obtained from the supine radiographs and MRI had no significant differences. The area under the curve (AUC) of the upright and supine AHI in the diagnosis of the FT tears were at 0.649 and 0.642 accuracy. Upright AHI 7.09 mm. had 27.9% sensitivity and 100% specificity in diagnosing FT tears with 64% accuracy (p<0.001). The upright AHI cut off value of 9.52 mm. had 60.5% sensitivity, 67.4% specificity, and 64% accuracy (p=0.01). The supine AHI 6.56 mm. had 32.6% sensitivity, 100.0% specificity, and 66.3% accuracy (p<0.01). Supine AHI cut off value of 7.42 mm. had 41.9% sensitivity, 86.0% specificity, and 64.0% accuracy (p=0.004). The inter- and intra-rater reliability of AHI measurement in 3 views were of substantial to almost perfect agreement (0.668-0.824).Conclusion: The AHI in supine radiographs were significantly lower than upright shoulder radiographs in all groups as divided by severity of the rotator cuff tear and was comparable with the MRI. For AHI ≤ 7 mm. in upright shoulder radiographs remains as a good diagnostic test of full thickness rotator cuff tears, while this value was not relevant for use as the cut point in the supine radiographs and MRI shoulders.Level of evidence: Level III; Diagnostic studyClinical Relevance: The AHI measurement in supine and upright radiographs are reliable and reproducible. The AHI ≤ 7 mm. in upright shoulder radiographs remains as a good diagnostic test of full thickness rotator cuff tears, while this value was not relevant for use as the cut point in the supine radiographs and MRI shoulders.
Persistent Airflow Obstruction: A Marker of a Severe Asthma Cohort – Inflammatory, Functional and Pathological Features
Authors: Carvalho-Pinto Regina Maria , Athanazio Rodrigo Abensur , Ferreira Diogenes Seraphin , Mauad Thais , Dolhnikoff Marisa , Rached Samia , Fernandes Frederico Leon Arrabal , Rabe Klaus F , Cukier Alberto , Stelmach Rafael 
Published: December 2021

Abstract
In our previous severe asthma cohort, 82% had fixed obstruction. Although they had greater airway smooth muscle area with decreased periostin, inflammation and remodeling weren’t associated with symptom control. High-resolution computed tomography (HRCT) and measures of small airways could be important tools for exploring asthma severity. Our aim was to describe characteristics associated to airflow obstruction in our non-controlled severe asthmatics according to obstruction profile. Persistent obstruction subgroups were also evaluated comparing disease severity. Methods: Patients were evaluated using asthma control questionnaire, induced sputum, spirometry, plethysmography, and Single Breath N2 washout test, at baseline, after oral corticosteroid (OC) and at the end of the treatment. They also underwent thorax HRCT and bronchoscopy with endobronchial biopsy.Results: Sixty-two were included and 77.4% classified as having persistent obstruction; 75% and 25% with moderate and severe obstruction, respectively. Pulmonary function values (FEV1) improved in both subgroups, except in severe. Patients with bronchial thickening, according to RB1 WA% and pi10, had significantly higher airway smooth muscle area.Conclusion: Patients with severe obstruction had greater lung function impairment, no response to OC or bronchodilator. This could be explained by airway remodeling characterized by higher airway smooth muscle area and bronchial thickness assessed by thorax HRCT.