bluuebunny/crossref_metadata_2025_split huggingface dataset:
Steps Towards Non-Smooth Multibody Dynamics
Authors: Pfeiffer Friedrich 
Published: November 2021

Abstract
Before the background of many thoughts about contact and impact behavior with and without friction in the past centuries a comprehensive theory appeared not before the second half of the last century, mainly connected with the names of Moreau in Montpellier and Panagiotopoulos in Thessaloniki. My former Institute has been part of this evolution focusing on non-smooth multibody dynamics and on large systems. The local development from simple impact to complex contact systems including all possible contact details will be subject of the paper, considering also the necessary mathematical evolution from classical multibody system theory with bilateral constraints and single-valued forces to non-smooth multibody system theory with unilateral constraints and set-valued forces. Paper will be illustrated by practical examples.
The protoliths of central Himalayan eclogites
Authors: Zhang Guibin , Wang Jiaxing , Webb A. Alexander G. , Zhang Lifei , Liu Shuaiqi , Fu Bin , Wu Chenguang , Wang Shuzhen 
Published: November 2021

Abstract
Eclogites represent the highest pressure conditions yet observed from rocks thrust to the surface in the central Himalaya. A detailed investigation of the protolith nature of these eclogites is needed to better understand pre-Himalayan geological history. Retrogressed eclogites were collected from Thongmön (Dingri County) and Riwu (Dinggye County), central Himalaya, China. We investigated the bulk rock major and trace elements, Sr-Nd isotopes, zircon geochronology, and Hf-O isotopes. These retrogressed eclogites experienced five stages of metamorphic evolution from prograde amphibolite-facies to peak eclogite-facies, and high pressure granulites-facies, granulites-facies then final amphibolite-facies overprinting during exhumation. Geochemically, they are subalkaline basalts with high FeO contents and a tholeiitic affinity; trace elements show similarities with enriched mid-ocean ridge basalts. Bulk rocks have a wide range of εNd(t) values from −0.24 to +7.08, and an unusually wide range of initial 87Sr/86Sr ratios of 0.705961–0.821182. Zircon relict magmatic cores from both Thongmön and Riwu eclogites yield a consistent protolith age of ca. 1850 Ma, with enriched heavy rare earth element patterns and significant negative Eu anomalies. These relict cores have oxygen isotopes signatures of δ18O = 5.8–8.1‰, εHf(t) values of –4.85 to +9.59, and two-stage model ages (TDM2) of 1.91–2.81 Ga. Metamorphic overgrowth zircons yield much younger ages of ca. 14 Ma. Integration of all of the above data suggests that the protolith of these central Himalayan retrogressed eclogites might be Proterozoic continental flood basalts of the North Indian Plate, generated under a post-collisional extension setting during the assembly of the Columbia Supercontinent. Occurrence of both Neoproterozoic–early Paleozoic rocks and ca. 1.85 Ga rocks in the regional crystalline rocks may reflect either unrecognized sub-horizontal Main Central Thrust exposure(s) or exhumation of a deeply cut part of the Greater Himalayan Crystalline complex. In combination with previous reports of Late Cretaceous, Neoproterozoic, and similar but younger Paleoproterozoic protolith, it is clear that the central Himalayan eclogites originate from multiple sources of protolith.
Determinants of the adoption of injury risk reduction programmes in athletics (track and field): an online survey of 7715 French athletes
Authors: Ruffault Alexis , Sorg Marine , Martin Simon , Hanon Christine , Jacquet Lison , Verhagen Evert , Edouard Pascal 
Published: November 2021

ObjectivesTo identify individual characteristics associated with the adoption of injury risk reduction programmes (IRRP) and to investigate the variations in sociocognitive determinants (ie, attitudes, subjective norms, perceived behavioural control and intentions) of IRRP adoption in athletics (track and field) athletes.MethodsWe conducted a cross-sectional study using an online survey sent to athletes licensed with the French Federation of Athletics to investigate their habits and sociocognitive determinants of IRRP adoption. Sociodemographic characteristics, sports practice and history of previous injuries were also recorded. Logistic regression analyses and group comparisons were performed.ResultsThe final sample was composed of 7715 athletes. From the multivariable analysis, competing at the highest level was positively associated with IRRP adoption (adjusted OR (AOR)=1.66; 99.9% CI 1.39 to 1.99 and AOR=1.48; 99.9% CI 1.22 to 1.80) and presenting a low number of past injuries was negatively associated with IRRP adoption (AOR=0.48; 99.9% CI 0.35 to 0.65 and AOR=0.61; 99.9% CI 0.44 to 0.84), both during their lifetime and the current season, respectively. These results were supported by higher scores of sociocognitive determinants among athletes who reported IRRP adoption compared with other athletes.ConclusionSome characteristics of athletes seem to be associated with IRRP adoption either positively (competing at the highest level) or negatively (presenting a lower number of past injuries), whereas all the sociocognitive determinants tested appear to be linked to IRRP adoption. Since many athlete characteristics are difficult or impossible to change, IRRP promotion may be enhanced by targeting athletes’ beliefs and intentions to adopt an IRRP.
Acute respiratory illness and return to sport: a systematic review and meta-analysis by a subgroup of the IOC consensus on ‘acute respiratory illness in the athlete’
Authors: Snyders Carolette , Pyne David B , Sewry Nicola , Hull James H , Kaulback Kelly , Schwellnus Martin 
Published: November 2021

ObjectiveTo determine the days until return to sport (RTS) after acute respiratory illness (ARill), frequency of time loss after ARill resulting in >1 day lost from training/competition, and symptom duration (days) of ARill in athletes.DesignSystematic review and meta-analysis.Data sourcesPubMed, EBSCOhost, Web of Science, January 1990–July 2020.Eligibility criteriaOriginal research articles published in English on athletes/military recruits (15–65 years) with symptoms/diagnosis of an ARill and reporting any of the following: days until RTS after ARill, frequency (%) of time loss >1 day after ARill or symptom duration (days) of ARill.Results767 articles were identified; 54 were included (n=31 065 athletes). 4 studies reported days until RTS (range: 0–8.5 days). Frequency (%) of time loss >1 day after ARill was 20.4% (95% CI 15.3% to 25.4%). The mean symptom duration for all ARill was 7.1 days (95% CI 6.2 to 8.0). Results were similar between subgroups: pathological classification (acute respiratory infection (ARinf) vs undiagnosed ARill), anatomical classification (upper vs general ARill) or diagnostic method of ARinf (symptoms, physical examination, special investigations identifying pathogens).ConclusionsIn 80% of ARill in athletes, no days were lost from training/competition. The mean duration of ARill symptoms in athletes was 7 days. Outcomes were not influenced by pathological or anatomical classification of ARill, or in ARinf diagnosed by various methods. Current data are limited, and future studies with standardised approaches to definitions, diagnostic methods and classifications of ARill are needed to obtain detailed clinical, laboratory and specific pathogen data to inform RTS.PROSPERO registration numberCRD42020160479.
Delivery of healthcare provider’s lifestyle advice and lifestyle behavioural change in adults who were overweight or obese in pre-diabetes management in the USA: NHANES (2013–2018)
Authors: Davis-Ajami Mary Lynn , Lu Zhiqiang Kevin , Wu Jun 
Published: November 2021

ObjectiveThe purpose of this study is to examine the association between delivery of healthcare provider’s advice about lifestyle management and lifestyle behavioural change in pre-diabetes management in adults who were overweight or obese.DesignThis cross-sectional study included adults with body mass index (BMI) ≥25 kg/m2 and reporting pre-diabetes in USA. Outcomes included the prevalence of receiving provider’s advice on lifestyle management and patterns of practicing lifestyle change. The association between delivery of provider’s advice and lifestyle-related behavioural change in pre-diabetes management was examined.SettingUS Continuous National Health and Nutrition Examination Survey (2013–2018).ParticipantsA total of 1039 adults with BMI ≥25 kg/m2 reported pre-diabetes.ResultsOf eligible adults with pre-diabetes, 76.8% received provider’s advice about lifestyle change. The advice group showed higher proportions of ongoing lifestyle change than no advice group, including weight reduction/control (80.1% vs 70.9%, p=0.018), exercise (70.9% vs 60.9%, p=0.013) and diet modifications (83.8% vs 61.8%, p<0.001). After adjustment, those receiving provider’s advice were more likely to increase exercise (OR 1.63, 95% CI 1.12 to 2.38) and modify diet (OR 3.0, 95% CI 1.82 to 4.96).ConclusionOver 75% of US adults who were overweight or obese and reported pre-diabetes received healthcare provider’s advice about reducing the risk of diabetes through lifestyle change. Provider’s advice increased the likelihood of lifestyle-related behavioural change to exercise and diet.
Dysregulation of prostaglandins, leukotrienes and lipoxin A4in bronchiectasis
Authors: Bedi Pallavi , Ziegler Kerstin , Whitfield Phil D , Davidson Donald , Rossi Adriano Giorgio , Hill Adam T 
Published: November 2021

IntroductionBronchiectasis is characterised by excessive neutrophilic inflammation. Lipid mediators such as prostaglandins and leukotrienes have crucial roles in the inflammatory response. Further characterisation of these lipids and understanding the interplay of anti-inflammatory and proinflammatory lipid mediators could lead to the development of novel anti-inflammatory therapies for bronchiectasis.AimThe aim of our study was to characterise the lipids obtained from serum and airways in patients with bronchiectasis in the stable state.MethodsSix healthy volunteers, 10 patients with mild bronchiectasis, 15 with moderate bronchiectasis and 9 with severe bronchiectasis were recruited. All participants had 60 mL of blood taken and underwent a bronchoscopy while in the stable state. Lipidomics was done on serum and bronchoalveolar lavage fluid (BALF).ResultsIn the stable state, in serum there were significantly higher levels of prostaglandin E2(PGE2), 15-hydroxyeicosatetranoic acid (15-HETE) and leukotriene B4(LTB4) in patients with moderate–severe disease compared with healthy volunteers. There was a significantly lower level of lipoxin A4(LXA4) in severe bronchiectasis.In BALF, there were significantly higher levels of PGE2, 5-HETE, 15-HETE, 9-hydroxyoctadecadienoic acid and LTB4in moderate–severe patients compared with healthy volunteers.In the stable state, there was a negative correlation of PGE2and LTB4with % predicted forced expiratory volume in 1 s and a positive correlation with antibiotic courses.LXA4improved blood and airway neutrophil phagocytosis and bacterial killing in patients with bronchiectasis. Additionally LXA4reduced neutrophil activation and degranulation.ConclusionThere is a dysregulation of lipid mediators in bronchiectasis with excess proinflammatory lipids. LXA4improves the function of reprogrammed neutrophils. The therapeutic efficacy of LXA4in bronchiectasis warrants further studies.
Straw cigarette branding: misleading descriptors and a new Marlboro man
Authors: Grilo Graziele , Welding Kevin , Szklo André Salem , Cohen Joanna E , Clegg Smith Katherine 
Published: November 2021

BackgroundStraw cigarettes are hand-rolled tobacco in a corn straw, common in Brazil and believed to be less harmful by consumers. Traditionally consumed in rural areas and by men, a recent increase in use among young people in urban areas was observed. This study assessed marketing appeals of straw cigarette packaging in Brazil.MethodsFollowing a systematic protocol, unique straw cigarette packs were purchased in 2013, 2016 and 2019 from three cities: Manaus, Salvador and São Paulo. Packs were double-coded for the absence/presence of marketing appeals (ie, luxury/quality, masculinity, classic/timeless, flavours and less harm).ResultsThe number of unique straw cigarette packs purchased as part of the overall sample increased in the most recent collection: 2.3% (n=3), 1.3% (n=2) and 15.5% (n=27) in 2013, 2016 and 2019, respectively. Across the years, all packs presented luxury/quality elements (eg, images of crests); 93.8% (n=30) included the word ‘artisanal’. Masculine appeal (eg, images of men) was present on 56.3% (n=18) of packs. Almost half had classic/timeless elements, including the words ‘tradition’/‘original’. In 2019, 59.3% (n=16) of the packs were flavoured compared with none in previous years. Over a quarter of all packs presented a less harm appeal (eg, ‘smooth’).ConclusionWe identified an increase in availability of unique straw cigarette packs, strong branding and use of misleading descriptors on the packs. The adoption of plain packaging and the implementation of Brazil’s additive ban could help to reduce the appeal of straw cigarettes and curb the current increase in use among youth.
Profile of menthol cigarette smokers in the months following the removal of these products from the market: a cross-sectional population survey in England
Authors: Kock Loren , Shahab Lion , Bogdanovica Ilze , Brown Jamie 
Published: November 2021

IntroductionIn May 2020, the EU Tobacco Products Directive ban on the sale of menthol cigarettes was implemented in England. This study examined the prevalence of menthol cigarette smoking after the ban, according to sociodemographic and smoking characteristics.MethodsCross-sectional data came from a representative survey of current smokers (18+) in England (unweighted n=2681) between July 2020 and June 2021. The weighted prevalence of menthol cigarette smoking as a proportion of total cigarette smoking was calculated, log-binomial regression explored trends over time, and χ2statistics assessed the relationship between menthol smoking, sociodemographic and smoking characteristics. Sources of purchase of menthol cigarettes were explored.ResultsBetween July 2020 and June 2021, 15.7% (95% CI 14.5 to 17.1) of smokers reported smoking menthol cigarettes. The fitted non-linear trend supported no initial change followed by a possible reduction across April–June 2021 and fit the data better than linear and null (no change) models (χ2(2)=2519.7, p=0.06; χ2(3)=2519.7, p=0.006). Menthol cigarette smoking was more common among younger groups (16–24=25.2%; 25–34=19.9%) and women (19.4%). Menthol cigarette smokers showed lower cigarette dependence compared with other smokers. Past-6-month purchases of menthol cigarettes from any illicit or cross-border source declined from 30.1% in the last 6 months of 2020 to 17.5% in the first 6 months of 2021.ConclusionsA substantial minority of current smokers in England reported menthol cigarette smoking between July 2020 and June 2021, despite the ban, possibly reflecting mitigation of restrictions by a variety of licit means, such as legal menthol accessories. The reduction in menthol smoking across April–June 2021 warrants further monitoring.
Measuring and Modeling Group Dynamics in Open-Source Software Development: A Tensor Decomposition Approach
Authors: Bock Thomas , Schmid Angelika , Apel Sven 
Published: November 2021

Many open-source software projects depend on a few core developers, who take over both the bulk of coordination and programming tasks. They are supported by peripheral developers, who contribute either via discussions or programming tasks, often for a limited time. It is unclear what role these peripheral developers play in the programming and communication efforts, as well as the temporary task-related sub-groups in the projects. We mine code-repository data and mailing-list discussions to model the relationships and contributions of developers in a social network and devise a method to analyze the temporal collaboration structures in communication and programming, learning about the strength and stability of social sub-groups in open-source software projects. Our method uses multi-modal social networks on a series of time windows. Previous work has reduced the network structure representing developer collaboration to networks with only one type of interaction, which impedes the simultaneous analysis of more than one type of interaction. We use both communication and version-control data of open-source software projects and model different types of interaction over time. To demonstrate the practicability of our measurement and analysis method, we investigate 10 substantial and popular open-source software projects and show that, if sub-groups evolve, modeling these sub-groups helps predict the future evolution of interaction levels of programmers and groups of developers. Our method allows maintainers and other stakeholders of open-source software projects to assess instabilities and organizational changes in developer interaction and can be applied to different use cases in organizational analysis, such as understanding the dynamics of a specific incident or discussion.
Thermal Stability of Transparent ITO/n-Ga2O3/n+-Ga2O3/ITO Rectifiers
Authors: Xia Xinyi , Xian Minghan , Ren Fan , Rasel Md Abu Jafar , Haque Aman , Pearton S. J. 
Published: November 2021

The thermal stability of n/n+
β-Ga2O3 epitaxial layer/substrate structures with sputtered ITO on both sides to act as rectifying contacts on the lightly doped layer and Ohmic on the heavily doped substrate is reported. The resistivity of the ITO deposited separately on Si decreased from 1.83 × 10−3 Ω.cm as-deposited to 3.6 × 10−4 Ω.cm after 300 °C anneal, with only minor reductions at higher temperatures (2.8 × 10−4 Ω.cm after 600 °C anneals). The Schottky barrier height also decreased with annealing, from 0.98 eV in the as-deposited samples to 0.85 eV after 500 °C annealing. The reverse breakdown voltage exhibited a negative temperature coefficient of −0.46 V.C−1 up to an annealing temperature of 400 °C and degraded faster at higher temperatures. Transmission Electron Microscopy showed significant reaction at the ITO and Ga2O3 interface above 300 °C, with a very degraded contact stack after annealing at 500 °C.
First Pass Effect With Neurothrombectomy for Acute Ischemic Stroke: Analysis of the Systematic Evaluation of Patients Treated With Stroke Devices for Acute Ischemic Stroke Registry
Authors: Jadhav Ashutosh P. , Desai Shashvat M. , Zaidat Osama O. , Nogueira Raul G. , Jovin Tudor G. , Haussen Diogo C. , Mueller-Kronast Nils , Liebeskind David S. 
Published: November 2021

Background and Purpose:
Achieving complete revascularization after a single pass of a mechanical thrombectomy device (first pass effect [FPE]) is associated with good clinical outcomes in patients with acute ischemic stroke due to large vessel occlusion. We assessed patient characteristics, outcomes, and predictors of FPE among a large real-world cohort of patients (Systematic Evaluation of Patients Treated with Stroke Devices for Acute Ischemic Stroke registry).

Methods:
Demographics, clinical outcomes, and procedural characteristics were analyzed among patients in whom FPE (modified Thrombolysis in Cerebral Infarction 2c/3 after first pass) was achieved versus those requiring multiple passes (MP). Modified FPE and modified MP included patients achieving modified Thrombolysis in Cerebral Infarction 2B-3. Primary outcomes included 90-day modified Rankin Scale (mRS) score and mortality.

Results:

Among 984 Systematic Evaluation of Patients Treated with Stroke Devices for Acute Ischemic Stroke patients, 930 had complete 90-day follow-up. FPE was achieved in 40.5% (377/930) of patients and MP in 20.0% (186/930). Baseline characteristics were similar across all groups. The FPE group had fewer internal carotid artery occlusions compared with MP (
P
=0.029). The FPE group had faster puncture to recanalization time (
P
≤0.001), higher rates of 90-day mRS score of 0 to 1 (52.6% versus 38.6%,
P
=0.003), mRS score of 0 to 2 (65.4% versus 52.0%,
P
=0.003), and lower 90-day mortality compared with the MP group (12.0% versus 18.7%,
P
=0.038). Similarly, compared with modified MP patients, the modified FPE group had fewer internal carotid artery occlusions (
P
=0.004), faster puncture to recanalization time (
P
≤0.001), and higher rates of 90-day mRS score of 0 to 1 (
P
=0.002) and mRS score of 0 to 2 (
P
=0.003).

Conclusions:
Our findings demonstrate that FPE and modified FPE are associated with superior clinical outcomes.
Tenecteplase Improves Door‐to‐Needle Time in Real‐World Acute Stroke Treatment
Authors: Hall Jillian , Thon Jesse M. , Heslin Mark , Thau Lauren , Yeager Terri , Siegal Taylor , Vigilante Nicholas , Kamen Scott , Tiongson Justin , Jovin Tudor G. , Siegler James E. 
Published: November 2021

Background
We report the interim results of a process improvement initiative at a comprehensive stroke center in which all tPA (tissue‐type plasminogen activator)–eligible patients were given tenecteplase for acute ischemic stroke.

Methods
We retrospectively analyzed a prospectively maintained single‐center registry of consecutive patients with acute ischemic stroke treated at our comprehensive stroke center emergency department or transferred for further care. Patients treated with alteplase (tPA) before the process improvement initiative (October 2019–April 2020) were compared with those treated with tenecteplase (May 2020–July 2021). The primary efficacy outcome was the Target: Stroke Phase II recommendation of door‐to‐needle (DTN) time ≤45 minutes. Backward stepwise logistic regression was used to estimate an independent effect of tenecteplase against DTN time ≤45 minutes. Two contemporaneous, negative controls (time to first emergency department antibiotic for patients who presented with infectious symptoms and door‐to‐groin puncture for thrombectomy) were evaluated to confirm DTN time was unrelated to emergency department and other stroke treatment throughput.

Results

Of the 113 included patients, 53 (47%) received tenecteplase. DTN time was significantly faster in patients treated with tenecteplase (median, 41 [interquartile range, 34–62] minutes versus 58 [interquartile range, 45–70] minutes;
P
<0.01), with no significant difference in symptomatic intracranial hemorrhage (2% versus 7%;
P
=0.37). Despite the higher proportion of tPA patients being transferred for care (with slower DTN time), tenecteplase remained independently predictive of DTN time ≤45 minutes (adjusted odds ratio, 3.96; 95% CI, 1.58–9.91). There was no difference in time to first emergency department antibiotic (
P
>0.05) or door‐to‐puncture (
P
>0.05) when similar periods were compared.

Conclusions
Tenecteplase was associated with faster DTN time when compared with tPA in those with acute ischemic stroke. This can likely be attributed to the ease of single bolus administration of tenecteplase.
Women’s Reproductive Rights and the Legacy of Religion in Ireland: The Eighth Amendment and Its Repeal
Authors: Hogan Linda 
Published: November 2021

Abstract
The changing religious landscape in Ireland is the context for this analysis of the implications of the insertion of the 8th Amendment to the Irish Constitution (which in 1983 inserted Article 40.3.3 into the Constitution to give the unborn an equal right to life with that of the mother) and its subsequent repeal in the 2018 referendum. It considers how women’s right to abortion (within the limits specified by the Regulation of Termination of Pregnancy Act 2018) can be vindicated in the context of claims to freedom of religion or belief and in light of the continuing institutional power of the Catholic church in the provision of healthcare. The broader political implications of the changing religious landscape are also considered, as is the question of whether and how the relationship between religion and politics in Ireland can be re-conceptualised.