bluuebunny/crossref_metadata_2025_split huggingface dataset:
¿Son válidos los argumentos evolutivos desacreditadores en contra de la ciencia cognitiva creacionista de la religión?
Authors: Sierra Jorge 
Published: February 2021

Según Plantinga, la identificación de los mecanismos cognitivos (postulados por la ciencia cognitiva de la religión (CCR) para explicar la creencia en Dios) con el sensus divinitatis, permite construir un argumento a favor de la racionalidad del teísmo e, incluso, otro a favor de su verdad. El objetivo de este texto es mostrar de qué manera se puede socavar tal argumento de la ciencia cognitiva creacionista de la religión (CCCRR) a favor del teísmo, apoyándome en 2 argumentos evolutivos desacreditadores (AED) inspirados en Hume. Los AED contra la racionalidad de la creencia religiosa parten de la afirmación de que tal creencia es causada por procesos que no rastrean la verdad y llegan a la conclusión de que dicha creencia es injustificada o incluso falsa. Hume desarrolla un AED con base en la idea de irracionalidad motivada y de la ilusión de control, y un AED basado en la diversidad religiosa, que intentan mostrar que tales mecanismos no son fiables en la generación de la creencia teísta. Sostendré que estos 2 argumentos permiten poner en serios aprietos a los defensores de la racionalidad externalista del teísmo y que, la apelación de Plantinga a los efectos epistémicos del pecado (para justificar el mal funcionamiento del sensus divinitatis y hacer frente a los AED), fracasa por varias razones y porque es posible desarrollar un argumento lógico cancelador en contra de la CCCRR.
Developmental Toxicity of the Neural Tube Induced by Titanium Dioxide Nanoparticles in Mouse Embryos
Authors: Mohamadzadeh Nahid , Zirak Javanmard Masoumeh , Karimipour Mojtaba , Farjah Gholamhosain 
Published: February 2021

Background: This study investigated the potential effects of Titanium dioxide nanoparticles (Tio2NPs) followed by maternal gavage on fetal development and neural tube formation during pregnancy in mice.
Methods: Thirty pregnant mice were randomly divided into five main study groups including the untreated control and 4 experimental groups (n=6 per group). The control group was treated with normal saline and the experimental groups were orally treated with doses of 30, 150, 300, and 500 mg/kg Body Weight (BW) of Tio2NPs during pregnancy. On gestational day 16 and 19 (n=3 per group), pregnant mice were euthanized and then examined for neural tube defects and compared with control. Serial transverse sections were prepared in both cranial region and in lumbar region of spinal cord.
Results: Treatment with Tio2NPs resulted in low fetal weight and short length, dilation of lateral ventricle, thinning of cerebral cortex and spinal cord, spina bifida occulta and an increase in the number of apoptotic neurons in exposed embryos at doses of 300 and 500 mg/kg (p<0.05).
Conclusion: It seems that exposure to nanoparticles of Tio2 during pregnancy induces growth retardation and for the first time, teratogenicity of this nanomaterial in neural tube development and induction of defects such as spinal bifida, reduction in cortical thickness and dilatation of lateral ventricles were verified which can be related to incidence of apoptosis in central nervous system.
The effect of low-level laser therapy and stress on wound healing in rats
Authors: Dalband Mohsen , Azizi Shahabaldin , Karimzadeh Mahdieh , Asnaashari Mohammad , Farhadinasb Abdullah , Azizi Mahdokht , Ramezani Mazaher 
Published: February 2021

Background: Many studies have been performed on the effect of low level laser on wound healing which has been associated with different and sometimes contradictory results. On the other hand, considering that stress may affect the immune system the fact that it may delay wound healing has also been addressed. Therefore, the present study aimed to investigate the simultaneous effect of low level laser therapy and stress on wound healing at the three levels of histology (histological changes), biomechanics (stress and strain assessment) and macroscopic (wound size).
Methods: In this interventional study, 72 male Wistar rats (8-10 weeks old, weight range: 240 to 330 g) were randomly divided into three treatment groups and one control group. (18 per group). In all the rats, a 2.5 cm full-thickness skin incision was made on the dorsal spine. Intervention was performed from day 1 to day 21 every other day with Kals-DX61 laser (cap s) with wavelength: 660 nm, dose 3 J / cm2, 100 sec and power density 30 mW / cm2. Then, wound size was measured weekly until the third week (day 21). Then, tension metric tests were performed to evaluate the stress and strain of the restored tissue. At the end of each week, three animals from each group were sacrificed for histopathological evaluation.
Results: There was a significant difference between the stress / no laser and laser/no stress groups in all stages of evaluation. Mean and standard deviation of stress and strain were not significantly different in the study groups.
Conclusion: Stress can potentially slow the wound healing process, while receiving low level laser therapy speeds up the wound healing process, although in the end there was no significant difference in biomechanical characteristics between the groups.
Constitutional Complaint in Indonesia Through the Lens of Legal Certainty
Authors: Wico Standy , Michael Michael , Sunarto Patricia Louise , Anastasia Anastasia 
Published: February 2021

To date, there is no trial mechanism for Indonesian citizens to claim their rights through the constitutional complaint, even if the Constitutional Court has existed since 2003. In fact, civil rights guaranteed in the 1945 Constitution are often ignored by the government even though these rights are essential in promoting the rule of law. This paper aims to revisit the range of constitutional complaints and further consequences about the legal certainty by taking into account the rationale of civil rights protection following the establishment of the Constitutional Court for adjudicating civil complaints. This study uses juridical research with normative and comparative approaches. In this context, a constitutional complaint is different from the judicial review for which, the actions of government officials are deemed to be detrimental and violate the constitutional rights of citizens. Rather, it is an adjudication for protecting civil rights when it is found the constitutional rights are breached by the government so that each citizen has legal standing before the Constitutional Court. As for the effort to apply legal certainty to constitutional complaints, a legal basis is needed, namely the laws that regulate and their application. By doing so, it can be implemented after amending the 1945 Constitution that outlines the additional power-wielding to the Constitutional Court.
KEYWORDS: Constitutional Complaint, Constitutional Court, Indonesian Constitution.
Eksplorasi Etnomatematika pada Pembuatan Kubah Masjid Berbahan Stainless Steel sebagai Bahan Lembar Kerja Siswa
Authors: Annisa Nurul , Sugiarti Titik , Monalisa Lioni Anka , Sunardi Sunardi , Trapsilasiwi Dinawati 
Published: February 2021

Ethnomatics are cultural practices related to mathematical activities such as grouping, counting, calculating, designing buildings or tools, determining locations. This research was conducted at the Soponyono Dome Company, Wirolegi, Jember. The purpose of this study is to describe ethnomatematics in the manufacture of stainless steel mosque domes and produce student worksheets. This research is a type of qualitative research with ethnographic approach. Data collection methods used are observation, interviews and documentation. The subjects of this research are the owner of the company and four dome craftsmen. Geometry concepts or elements found include: congruent, flat shapes (rectangle, irregular hexagon, circle segment, trapezoid), space structures (cylinder, truncated ball, cone, and truncated cone), geometrical transformations (dilatation), and mathematical activity (measuring activity, counting activity, and design activity). The results of the study were made as worksheet material for Grade IX students with the subject of constructing curved side spaces of tube and cone material.

Keywords: Ethnomatematics, Mosque Dome, Student Worksheet.
Analisis Analisis Berpikir Kritis Siswa SMP dalam Menyelesaikan Soal Pecahan ditinjau dari Gaya Belajar
Authors: Muslimah Ayu Imamatul 
Published: February 2021

In learning activities, one of the efforts that can be done to improve students' learning abilities is to support learning styles that are following the objectives so that learning can be done effectively. This research was conducted at Junior High School 1 Kalisat, located at Jl. Diponegoro 52 Kalisat, Jember. This study aims to describe the students' critical thinking processes in solving fraction problems in terms of visual, auditory and kinesthetic learning styles. Data collection techniques used consisted of learning style questionnaires, critical thinking tests, and interview method. The subjects in this study were 6 students consisting of 2 students who represented visual, auditory, and kinesthetic learning styles. Based on data analysis, the results show that students with a visual and kinesthetic learning style meet five indicators of critical thinking, namely basic clarification, basic skills, concluding, further clarification, and strategies and tactics. Students with auditory learning styles meet the four indicators of critical thinking namely basic clarification, building basic skills, further clarification, and concluding. While students with auditory learning styles are less able to meet the indicators of strategies and tactics.
Keywords: Critical Thinking, Learning Styles, Fraction Problems
ANALISIS KETERAMPILAN GEOMETRI SISWA DALAM MENYELESAIKAN MASALAH TRANSFORMASI DAN KESEBANGUNAN GEOMETRI RUMAH ADAT OSING
Authors: AFNENDA ADINDA BEAUTY 
Published: February 2021

This research aims to determine the geometry ability of class XI students in solving transformation problems and geometric building problems of the Osingese traditional house. The subjects of this study were 6 students of class XI MIPA 4 SMAN 1 Tegaldlimo. Students are given questions of geometric transformation skills and geometric building problems tests, followed by interviews. This type of research is a qualitative descriptive study. The results obtained in the transformation of skills are students with high math scores first have all skills, students with low math scores first have all skills except applied skills, students with medium mathematics scores first only have drawing skills and applied skills, and students with moderate math scores second and second low math score students only have drawing skills. As for geometric building problem skills, almost all students have all skills. The second moderate math score students and first low math students had all skills except, applied skills.
Urban planning, policymaking and scenarios of land uses' design
Authors: Vargas-Hernández José G. 
Published: February 2021

This paper is aimed to analyze the implications between urban planning, policymaking and scenarios of land uses’ design. The analysis assume that urban planning and design contribute to the quality of a city’s land uses and landscapes that are related to factors that improve qualitatively urban areas and the upgrading neglected areas. It begins analyzing the urban design and planning and its relationships with the urban land uses, policymaking and strategies to resume in design scenarios. It is concluded that urban planning, policymaking and design of land uses are relevant activities to manage urban land resources to achieve sustainable urban development.

Keywords: Design, land uses, policy making, scenarios, urban planning.
ANALISIS QUALITY OF SERVICE (QOS) PADA JARINGAN INTERNET SMK NEGERI 7 JAKARTA
Authors: Aprianto Budiman  , M. Ficky Duskarnaen  , Hamidillah Ajie  
Published: February 2021

Hampir semua kegiatan di SMK Negeri 7 Jakarta memanfaatkan fasilitas Internet. Baik itu untuk proses kegiatan belajar mengajar, maupun pada bagian staff tata usaha. Untuk mendukung semua kegiatan tersebut diperlukan kinerja jaringan yang baik dan handal. Koneksi jaringan yang buruk pastinya akan menggagu proses kegiatan tersebut. Penerapan Quality of Service (QoS) merupakan sebuah solusi dari masalah diatas Quality of Service (QoS) merupakan teknik untuk mengelola bandwidth, delay, packet loss dan jitter untuk aliran dalam jaringan. Tujuan dari mekanisme QoS adalah mempengaruhi setidaknya satu diantara empat parameter dasar QoS yang telah ditentukan. Untuk mengetahui seberapa besar nilai QoS pada jaringan Internet SMK Negeri 7 Jakarta, maka harus dilakukan sebuah analisis parameter QoS. Analisis Quality of Service pada jaringan Internet SMK Negeri 7 Jakarta menekankan proses monitoring dan pengukuran parameter QoS yaitu throughput, delay, packet loss dan jitter. Tools yang digunakan untuk pengukuran parameter QoS adalah Axence Net Tools Pro 5.0 dan bandwidth monitor speedtest apps. Hasil akhir yang didapatkan setelah melakukan pengukuran QoS adalah jaringan Internet SMK Negeri 7 Jakarta masuk pada kategori sedang berdasarkan standarisasi TIPHON dengan nilai indeks 2,14.
Desarrollo de un programa de educación acuática en la escuela indígena de la comunidad seri
Authors: Costa Urrutia Paula , Becerra Viviana , Becerra Fabián , González Osiris , Ratti Carolina , Fernández Sebastián , Chaparro Manríquez Jesús Antonio , Hernández Acevedo Haide , Santana Meza Haide Yoselin , Ramírez Cruz Alejandro , Pérez Raymundo , Rodríguez-Arellano Eunice , Granados Julio , Argüelles Diaz-González Antonio , Álvarez Fariña Rafael 
Published: February 2021

Antecedentes: Las prácticas acuáticas contribuyen al desarrollo motriz y disminuyen la probabilidad de ahogamientos. Su implementación es particularmente importante en comunidades costeras, dada la relación de sus integrantes con el entorno marino.
Objetivos: Por lo que se llevó a cabo una escuela de verano que tuvo como objetivo la adaptación, de la comunidad indígena Seri de Punta Checa, norte de México, al medio acuático en un entorno natural.
Método: Las actividades fueron retos motores para desarrollar habilidades y destrezas de supervivencia en el ambiente acuático; estaciones de habilidades de juego grupal; y enseñanza de técnica.
Resultados: Participaron 48 niños en total, con un promedio de asistencia de dos días por semana. Ninguno de los participantes sabía nadar antes del programa y todos adquirieron habilidades de supervivencia básicas. Los niños mayores de 8 años desarrollaron habilidades motrices y lograron completar circuitos con estaciones cuyas distintas los obligaban a poner en práctica estas habilidades. Los niños de 6 a 8 años alcanzaron una fase preliminar de desarrollo, puesto que fueron capaces de realizar algunas actividades en lugares poco profundos. Por medio de dibujos, los niños expresaron sus intereses, y la natación estuvo entre sus actividades preferidas.
Conclusiones: Los niños, las familias, los docentes y las autoridades educativas consideraron que el programa había tenido resultados positivos, lo cual resalta la importancia de incluir la adaptación al medio acuático en el plan de estudios. Esto, contribuiría a la seguridad acuática y el desarrollo de la competencia motriz de los niños, sino también a una mayor disposición al aprendizaje curricular.
Influencia de la interacción práctica entre padres e hijos en el proceso de adquisición de habilidades acuáticas.
Authors: Dos Santos Bruna F. , De Freitas Edson T. , Dos S. Mineiro Aurea , Madureira Fabrício 
Published: February 2021

Antecedentes: Teniendo en cuenta, las limitadas experiencias de interacción entre padres e hijos, en el actual contexto tecnológico, trabajos que se profundicen en identificar los posibles efectos de experiencias que maximizan el acercamiento de la familia con actividades físicas deben ser incentivados.
Objetivos: Analizar los efectos de un programa de interacción práctica entre padres e hijos en el proceso de adquisición de habilidades acuáticas (HA).
Método: El estudio se compuso de 16 sesiones de 50' cada uno, con 17 niños de 5 (± 1,2) años, divididos en GE (donde los padres participaron en las clases de natación) y GC (donde los padres no participaron en las clases). El análisis del aprendizaje de las HAs fue realizado a través de un checklist, compuesto por 18 ítems.
Resultados: Después del análisis de los datos se puede observar que el GE presentó inicialmente un 79% de aprovechamiento en el boletín de evaluación y después del programa presentó una mejora de 93%. El GC presentó inicialmente 72% de aprovechamiento y después un 84%. Con respecto a la comparación de los momentos pre y post para las tareas cuantitativas siendo ellas: control de esfuerzo por tiempo prolongado, reflejado en la distancia total recorrida en 5' de nado continuo; el metraje total nadado en 45'; el tiempo de apnea estática, se puede identificar diferencia estadística significativa para ambos grupos.
Conclusiones: A pesar de la mejora de los dos grupos el GE presentó resultados más significativos en 3 tareas que involucra mayor demanda de complejidad y motivación.
Revisión bibliográfica de las prácticas acuáticas escolares en argentina. propuesta de intervención
Authors: Albarracín Pérez Apolonia , Rocha Daniela 
Published: February 2021

Antecedentes: Las prácticas acuáticas en la educación física escolar permiten a los niños, niñas y adolescentes experimentar y disfrutar junto a otros diversas y amplias posibilidades de movimiento en un medio diferente al habitual. Es por ello, que se considera necesario indagar en el sistema educativo argentino, en busca de propuestas y normativas que promuevan la enseñanza en el medio acuático.
Objetivos: Identificar los marcos normativos y curriculares de Argentina que regulen la enseñanza de actividades acuáticas escolares, y contribuir a la implementación de propuestas en el medio acuático, a partir de la construcción de orientaciones didácticas.
Método: Se ha realizado una revisión bibliográfica de diferentes documentos y estudios de Argentina en búsqueda de antecedentes e información sobre las prácticas acuáticas escolares en la Educación Secundaria.
Resultados: Se analizaron artículos y documentos que presentan antecedentes de estudios referidos a prácticas acuáticas escolares en Argentina, así como también se realizó un análisis de los documentos oficiales a nivel jurisdiccional, vinculados a la enseñanza de las actividades acuáticas en la educación física escolar en Argentina. Por último, se elabora una propuesta práctica de intervención centrada en orientaciones didácticas que puedan ser de utilidad para la elaboración de diferentes propuestas que promuevan aprendizajes significativos en el medio acuático.
Conclusiones: Se destaca el valor de la enseñanza de prácticas acuáticas, para que sea promovida desde el Estado dentro del sistema educativo en Argentina, y se pondera el lugar protagonista de la escuela y los profesores de educación física. Resulta significativo el alcance de este estudio al analizar veintidós de veinticuatro jurisdicciones del territorio nacional, e identificar que dieciocho de ellas proponen contenidos vinculados a las prácticas acuáticas en el área de educación física.
Development and validation of a ferroptosis-related prognostic model in pancreatic cancer
Authors: Qiu Chen-jie , Wang Xue-bing , Zheng Zi-ruo , Yang Chao-zhi , Lin Kai , Zhang Kai , Tu Min , Jiang Kui-rong , Gao Wen-Tao 
Published: February 2021

Abstract
Background: The purpose of this study was to identify ferroptosis-related genes (FRGs) associated with the prognosis of pancreatic cancer and to construct a prognostic model based on FRGs. Methods: Based on pancreatic cancer data obtained from The Cancer Genome Atlas database, we established the prognostic model from 232 FRGs. A nomogram was constructed by combining the prognostic model and clinicopathological features. Gene Expression Omnibus datasets and tissue samples obtained from our center were utilized to validate the model. Relationship between risk score and immune cell infiltration was explored by CIBERSORT and TIMER.Results: The prognostic model was established based on four FRGs (ENPP2, ATG4D, SLC2A1 and MAP3K5) and can be an independent risk factor in pancreatic cancer (HR 1.648, 95% CI 1.335-2.035, p < 0.001). Based on the median risk score, patients were divided into a high-risk group and a low-risk group. The prognosis of the low-risk group was significantly better than that of the high-risk group. In the high-risk group, patients treated with chemotherapy had a better prognosis. The nomogram showed that the model was the most important element. Gene set enrichment analysis identified three key pathways, namely, TGFβ signaling, HIF signaling pathway and adherens junction. The prognostic model can also affect the immune cell infiltration, such as macrophages M0, M1, CD4+T cell and CD8+T cell. Conclusion: A ferroptosis-related prognostic model can be employed to predict the prognosis of pancreatic cancer. Ferroptosis can be an important marker and immunotherapy can be a potential therapeutic target for pancreatic cancer.
Prediction of Inflammatory Bowel Diseases using Genetic Risk Score in Asian populations
Authors: Abedian Shifteh , Wong Sunny H , Sommeren Suzanne Van , Takahashi Atsushi , Cheon Jae Hee , Sood Ajit , Vahedi Homayoon , Yamazaki Keiko , Kim Won Ho , K Thelma B , Daryani Nasser E , Kubo Michiaki , Yang Suk-Kyun , Banerjee Rupa , Malekzadeh Reza , Weersma Rinse K. , Ng Siew C. , Alizadeh Behrooz Z. 
Published: February 2021

Abstract
Background and Aims:

The incidence of Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and Ulcerative colitis (UC), is rising in Asian populations. We undertook a cross-population study to explore whether genetic risk scores (GRS) of IBD, CD and UC could explain their occurrence, and whether they can be used to predict disease occurrence in general populations from East Asia (EA) and Central Asia (CA).
Methods

We studied 9,698 subjects – 4,733 IBD patients (2,003 CD; 2,730 UC) and 4,965 matched controls – who had been genotyped using Immunochip. The subjects were from three East Asian (Japan, South Korea and China) and two Central Asian populations (India and Iran). We generated GRS for each population by combining information from up to 201 genome-wide significant IBD-associated variants to summarize the total load of genetic risk for each phenotype. We then estimated the explained variance and predictability of IBD using the GRS.
Results

IBD GRS could explain up to 4.40% and 4.14% of IBD variance at a significant level in East Asian and Central Asian populations, respectively, but, given a prevalence of 0.01% and 0.04% for IBD, these yield limited predictive probability. GRS for CD and UC separately proved less significant than GRS for IBD.
Conclusion

GRS alone can explain only a limited percentage of disease occurrence (< 5% of disease susceptibility) and cannot be used to predict IBD in Asian populations at this time. Our results highlight the significant missing heritability, which may be due to genetic epistasis, gene-environment interactions, or rare variants.