bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Water Resource Carrying Capacity Based on Fuzzy Matter-element Model
Authors: Wang Yumin , Ji Zixiang 
Published: March 2021

Abstract
Water resources carrying capacity (WRCC) is a significant foundation for scientific management of water resources that connected with development of water resources, population, society, and economy. With the rapid development of economy and society, the shortage of water quantity is becoming one of the most profound global issues. In this paper, to evaluate WRCC scientifically and reasonably, index system of WRCC was established and applied for assessing the WRCC of four cities in China by fuzzy matter element (FME) model comprehensively. The indices were weighted by entropy method. The WRCC of four cities of Beijing, Tianjin, Shanghai, and Chongqing are 2.620, 2.503, 2.590, and 2.457, respectively. The results indicated that the WRCC of four cities decreased in the order of Chongqing > Tianjin > Shanghai > Beijing. The method proposed can be applied to other evaluation issues, and the results can help managers realize the importance of water resources in developing the economy and society.
Simulation Analysis on Drainage Consolidation Characteristics of Hydraulic Fill Soft Soil
Authors: Yu Shengyou , Quan Xiaojuan , You Kaikai , Ding Jihui , Gan Yu 
Published: March 2021

Abstract
Based on the treatment of dredger fill soft soil foundation in Eastern Shantou, Guangdong Province, consolidation theory and numerical simulation based on composite consolidation coefficient are used to study the consolidation characteristics of dredger fill soft soil, and the results are compared with the field monitoring results. The calculation results show that the theoretical consolidation degree of the site is 93.4%, which is basically consistent with the final consolidation degree of field monitoring. In the first two stages of surcharge loading, field monitoring is faster than theoretical calculation. The field monitoring value of the final settlement is 1342 mm, which is about 10% less than the theoretical value. The final average consolidation degree of the two models is 97.9%, which is 4.7% more than the field monitoring value. The results show that the pore water pressure law is obvious, the dissipation rate is about 16% higher than the field monitoring value, and the consolidation effect is more obvious. The numerical simulation of the composite coefficient model has certain applicability and can be used to guide the design and construction of similar projects.
Experimental Study on On-line Monitoring Technology of Hydropower Station Induced Discharge
Authors: Qi Guihua , Yang Chunlin , Du Changqing 
Published: March 2021

Abstract
In this paper, the water level, tail water level and active power of hydropower generating units are collected and transmitted in real time by using the water level gauge, power collector and other measuring and sensing instruments. Using MATLAB least square fitting simulation algorithm, the three-dimensional surface function of hydraulic turbine characteristics is obtained, and the efficiency of turbine operating point is calculated based on this function. Through the calibration calculation of the background data center, the reference flow of the hydropower station can be obtained on-line in real time, and verified by the comparison test between the reference flow system of the hydropower station and the Nanrui fu911 ultrasonic flowmeter. The results show that the flow measurement data of hydropower station reference flow system and ultrasonic flowmeter have the same change trend, and the flow measurement data of hydropower station reference flow system meet the requirements of class I accuracy class < 9% specified in GB 50179-2015 “Specification for river flow measurement”, which provides an effective method for on-line monitoring of reference flow of hydropower station.
Ecological Development and Framework of Reverse Logistics System for Venous Industry Parks
Authors: Xun Wei , Cheng Guoping , Wang Chen 
Published: March 2021

Abstract
Eco-industrial park has become the trend of the development of industrial parks in the world, and the shortage of resources is also a common problem faced by all countries, Combining the development of ecological parks with resource recycling and reuse is a current international hot spot. China has been exploring for more than 20 years, but in the complex social and economic system, the system mechanism of circular economy is still being explored, in which the construction of reverse logistics system has become a breakthrough. With the rapid development of information technologies such as the Internet of Things and mobile Internet, the venous Industry as a new form of circular economy is facing major opportunities. This article combines objective optimization and spatial analysis technology to explore the structure and operational performance of the reverse logistics system in the venous Industry, and provides useful countermeasures for the development of circular economy.
Research on Anti-UV Aging of Asphalt Surface Layer Paved with Colored Epoxy Surface Material
Authors: Liu Shuxiang , Yang Jingli 
Published: March 2021

Abstract
The colored epoxy surface was one of the most popular preventive maintenance technologies in road engineering. And because of the molecular of epoxy materials, the UV-aging resistance of that was poor. In the paper the effect and mechanism of UV absorber on the UV-aging resistance of epoxy surface had been studied in different aspects. Tensile properties were used as performance index to evaluation the effects of ultraviolet light absorbers on the mechanical properties of the colored epoxy surface structure materials. The aging degree of epoxy material under the long-term sunlight exposure was simulated by UV-aging test and the mechanism of light absorbers of the surface structure materials was analysed by infrared spectroscopy (FTIR) and scanning electron microscope (SEM). Finally, the wheel rutting test, trabecular bending test, freeze-thaw split test and indirect split test were conducted to evaluate the road performance of colored epoxy surface before and after added UV-light absorber. The test results showed that the optimal dosage of light absorber was 1%. The microscopic mechanism analysis showed that light absorber can effectively inhibit the decomposition of carbonyl groups, maintain the basic shape of the surface, and improve the aging resistance of the materials from the surface structure significantly. The road performances of the colored pavement with light absorber were significantly improved compared with that without adding light absorber. The intercept of fatigue curve of the one contained light absorber after UV aging was 2.6% higher and the gradient was 10.9% larger than those without light absorber. Light absorber improved the aging resistance of the epoxy surface pavement and other indexes of the road were all conformed to the specification.
Construction and Study of the Application of Novel Norfloxacin Fluorescent Probes
Authors: Lv Kuilin , Wan Detian , Wang Lei , Lv Yuguang 
Published: March 2021

Abstract
In this experiment, a fluorescent probe of tricyanohydrofuran-norfloxacin was successfully constructed. Fluorescence spectrophotometer was used to detect the fluorescence intensity of the system under the condition of the excitation wavelength was 362nm and the emission wavelength was 448nm. The optimal experimental conditions were optimized (the concentration of the complex, the amount of norfloxacin, pH, temperature and reaction time). The optimal concentration of the complex in the system is in the range of 1.0×10−3-3.5×10−4 mol·L−1, the dosage was 0.6mL, and optimal dosage of norfloxacin was 3.0 ml, the optimum pH of the system was 5.5, under this condition the fluorescence intensity of the system was the strongest. At the same time, the intramolecular charge transfer reaction mechanism of fluorescent probe was studied. And testing the content of norfloxacin capsules, the results were satisfactory. A new testing method of norfloxacin content successfully created.
Two-phase Solvothermal Synthesis of MoO2/RGO Nanocomposites for Lithium-Ion Battery Anodes
Authors: Geng Qin , Su Xintai , Dong Fan , Wang Zhiming 
Published: March 2021

Abstract
Nowadays, it is necessary to develop the lithium-ion battery with higher capacity, lighter weight and thinner volume. Transition metal oxide, as a promising anode materials, has drawn much attention, as a result of its large capacity and high economic value. However, poor cycle stability greatly limits its practical applications. In this paper, MoO2/RGO nanocomposites were synthesized by a two-phase solvothermal method by adjusting the pH value to 2.0. Affected by the size of nanoparticles, the nanocomposites with MoO2 nanoparticles (100 nm) uniformly anchored on the RGO nanosheets exhibit a more superior electrochemical performance with a high capacity of 765.1 mAh g−1 after 50 cycles, which is expected to be a promising anode material for lithium-ion batteries.
Effects of silicic acid rate and application method on plant growth, yield components and yield of Oryza sativa L. var. MR284
Authors: Najib M Y M , Hasnuri M H , Izham M N N M , Fadzli A R M N 
Published: March 2021

Abstract
Silicon is one of the beneficial elements to the rice plant for plant growth and the effects could be detected particularly under the biotic and abiotic stress conditions. Plants take up silicon in a form of monosilicic acid from various sources of silicon. A pot experiment was conducted under a greenhouse condition to study the uptake of silicon by local Malaysian rice variety MR284 in a form of silicic acid. The experiment was carried out under 2 x 4 factorial design consist of two methods of silicic acid application namely foliar spray and drench method and four silicic acid rate at 0, 0.02, 0.04 and 0.06 mol L−1-set up in Complete Randomized Design (CRD) with four replications. Parameters measured were plant growth, yield component and grain yield. Paddy with foliar spray application of silicic acid had a better performance than of paddy with drench method in term of yield increment. The application of silicic acid did not have significant effects on panicle length, plant height and thousand grain weight. The number of tillers and number of panicles had increased with an increasing silicic acid rate, while percentage of filled grain and grain yield decreased with the increasing of silicic acid rate. The findings suggest that the ideal amount of silicic acid for optimum effects on growth and yield of paddy can be used at 0.02 mol L−1 as foliar spray application.
The Marxan model for determining no-catch zones based on conservation targets in the north-eastern region of Simeulue District
Authors: Aulia F , Rusdi M , Deli A , Fuadi A , Irham M , Indra I 
Published: March 2021

Abstract
Aceh Governor’s Decree Number 523/1297/2018 concerning the Determination of Reserve Reservation for Aceh Waters allows Pinang, Siumat and Simanaha Islands (PISISI) in the northeast region of Simeulue Island to become one of the conservation zones that have a no-take zone. Therefore, it is necessary to have a scientific analysis of the management and zoning plan especially in determining the location of the core zone (no-take zone). Determination of the core zone is the most important part in planning to protect coastal areas as a form of sustainable management of fish resources and the environment. The purpose of this study is to determine the location of no-take zones based on conservation targets that have high biodiversity values in the PISISI area of Simeulue Island. Therefore, the Marxan model is used which is a design plan for the conservation zoning design. The analysis shows that there are eight areas that can be used as a no-catch area based on coastal habitats, biodiversity, and high conservation value. The model results indicate that no-take zones will be able to protect 80% of conservation targets. Simulation results also show that the area of the no-take zone is around 2,283.89 ha.
Maternal Urinary Organophosphate Esters and Alterations in Maternal and Neonatal Thyroid Hormones
Authors: Percy Zana , Vuong Ann M , Xu Yingying , Xie Changchun , Ospina Maria , Calafat Antonia M , Hoofnagle Andy , Lanphear Bruce P , Braun Joseph M , Cecil Kim M , Dietrich Kim N , Yolton Kimberly , Chen Aimin 
Published: March 2021

Abstract
Production of organophosphate esters (OPEs), which represent a major flame-retardant class present in consumer goods, has increased over the past 2 decades. Experimental studies suggest that OPEs may be associated with thyroid hormone disruption, but few human studies have examined this association. We quantified OPE metabolites in the urine of 298 pregnant women from Cincinnati, Ohio, in the Health Outcomes and Measures of the Environment Study (enrolled 2003–2006) at 3 time points (16 and 26 weeks’ gestation, and at delivery), and thyroid hormones in 16-week maternal and newborn cord sera. Urinary bis(1,3-dichloro-2-propyl)-phosphate concentrations were generally associated with decreased triiodothyronine and thyroxine levels and increased thyroid-stimulating hormone levels in maternal and newborn thyroid hormones in quartile dose–response analyses and multiple informant models. There was weaker evidence for thyroid hormone alterations in association with diphenyl-phosphate and di-n-butyl-phosphate. Bis-2-chloroethyl-phosphate was not associated with alterations in thyroid hormones in any analyses. We did not observe any evidence of effect modification by infant sex. These results suggest that gestational exposure to some OPEs may influence maternal and neonatal thyroid function, although replication in other cohorts is needed.
Beliefs, Facilitating Factors, and Barriers in Using Personal Dosimeter among Medical Radiation Workers in a Middle-Income Asian Setting
Authors: Mohd Ridzwan Siti Farizwana , Bhoo-Pathy Nirmala , Wee Lei Hum , Isahak Marzuki 
Published: March 2021

AbstractThis qualitative study explores the medical radiation workers’ (MRWs) beliefs with the support of the theory of planned behaviour’s constructs regarding the use of personal dosimeters in order to identify the facilitating factors and barriers to practising good personal dose monitoring. The exploration was conducted through semi-structured face-to-face interviews with 63 MRWs from the public, private, and university hospitals. Belief statements from the informants were organized under the behavioural, normative, and control belief, as guided by the theory. A thematic analysis found that a majority of informants acknowledged the benefits of using dosimeters. However, several factors influenced the actual usage. The informants were hesitant to use the dosimeter as the loss of the device involved an expensive penalty. They also mentioned that delayed dosimeter supplies due to late budget approval in the hospitals and some other reasons had got them disconnected from the monitoring system. The workers’ attitudes and social norms highly induced their dosimeter usage as well; some perceived themselves to be at low risk for high exposure to radiation, and forgetfulness was also mentioned as a reason for lack of adherence. Device physical factor influenced low dosimeter use too. This study highlighted some unique findings in Asian settings. A better understanding of the underlying reasons for the lack of dosimeter use will be useful in developing strategies to increase good practices in personal radiation monitoring.
Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity
Authors: Niccoli Teresa , Kerr Fiona , Snoeren Inge , Fabian Daniel , Aleyakpo Benjamin , Ivanov Dobril , Sofola-Adesakin Oyinkan , Cryar Adam , Adcott Jennifer , Thornton Janet , Partridge Linda 
Published: March 2021

Abstract
Accumulation of amyloid beta peptides is thought to initiate the pathogenesis of Alzheimer's disease. However, the precise mechanisms mediating their neurotoxicity are unclear. Our microarray analyses show that, in Drosophila models of amyloid beta 42 toxicity, genes involved in the unfolded protein response and metabolic processes are upregulated in brain. Comparison with the brain transcriptome of early-stage Alzheimer's patients revealed a common transcriptional signature, but with generally opposing directions of gene expression changes between flies and humans. Among these differentially regulated genes, lactate dehydrogenase (Ldh) was up-regulated by the greatest degree in amyloid beta 42 flies and the human orthologues (LDHA and LDHB) were down-regulated in patients. Functional analyses revealed that either over-expression or inhibition of Ldh by RNA interference (RNAi) slightly exacerbated climbing defects in both healthy and amyloid beta 42-induced Drosophila. This suggests that metabolic responses to lactate dehydrogenase must be finely-tuned, and that its observed upregulation following amyloid beta 42 production could potentially represent a compensatory protection to maintain pathway homeostasis in this model, with further manipulation leading to detrimental effects. The increased Ldh expression in amyloid beta 42 flies was regulated partially by unfolded protein response signalling, as ATF4 RNAi diminished the transcriptional response and enhanced amyloid beta 42-induced climbing phenotypes. Further functional studies are required to determine whether Ldh upregulation provides compensatory neuroprotection against amyloid beta 42-induced loss of activating transcription factor 4 activity and endoplasmatic reticulum stress. Our study thus reveals dysregulation of lactate dehydrogenase signalling in Drosophila models and patients with Alzheimer's disease, which may lead to a detrimental loss of metabolic homeostasis. Importantly, we observed that down-regulation of ATF4-dependent endoplasmic reticulum-stress signalling in this context appears to prevent Ldh compensation and to exacerbate amyloid beta 42-dependent neuronal toxicity. Our findings, therefore, suggest caution in the use of therapeutic strategies focussed on down-regulation of this pathway for the treatment of Alzheimer's disease, since its natural response to the toxic peptide may induce beneficial neuroprotective effects.
Aligning industry interests with urban priorities to foster energy transitions: insights from two Chinese cities
Authors: Huang Ping , Yu Zhen 
Published: March 2021

Abstract
This article uses the Dimensions of Urban Energy Transitions (DUET) framework to analyse energy transitions in two Chinese cities at different development stages and provide insights into the mechanisms underlying decarbonised industrialisation. The results show that a ‘green’ coalition between industrial actors and local governments is critical to the initiation and scale-up of low-carbon innovations that provide strong endogenous incentives for proactive transitions. The study unveils the relevance of technology-specific characteristics and the potential countering effect of urban politics in shaping the outcomes of energy transitions, adding both nuance and depth to the DUET framework.
Ethnicity Influences Risk of Inflammatory Bowel Disease (IBD)-Associated Colon Cancer: A Cross-sectional Analysis of Dysplasia Prevalence and Risk Factors in Hispanics and Non-Hispanic Whites With IBD
Authors: Damas Oriana M , Raffa Gabriella , Estes Derek , Mills Grechen , Kerman David , Palacio Ana , Schwartz Seth J , Deshpande Amar R , Abreu Maria T 
Published: March 2021

Abstract

Background
Inflammatory bowel disease (IBD) is an emerging disease in Hispanics. In this study, we examine the prevalence of IBD-related colon dysplasia (IBD-dys) in Hispanics versus non-Hispanic whites (NHWs) and compare differences in established clinical and environmental risk factors.

Methods
We performed a cross-sectional analysis on adult Hispanics and NHWs with IBD who met criteria for colorectal cancer surveillance and were followed at our center between 2008 and 2018. Clinical variables and IBD phenotype were recorded. Lifestyle IBD-dys risk factors were examined, including smoking and lack of physical activity. Using multivariable regression, we compared the prevalence of IBD-dys in Hispanics versus NHW, using relevant covariates. Receiver operating characteristic and area under the curve were performed to find the best fitting model.

Results
A total of 445 IBD patients were included (148 Hispanics and 297 NHWs). IBD phenotype was similar between groups, except that Hispanics had shorter disease duration, a lower frequency of Crohn’s disease-related complications, and lower reported use of steroids. Frequency of surveillance colonoscopies was similar between Hispanics and NHW. There were no differences in median body mass index between Hispanics and NHW [26.5 (IQR 6.0) vs 25.0 (IQR 6.0), P = 0.40]. Hispanics were less likely than NHW to consume alcohol but smoking history was similar between groups. Three out of 148 Hispanic patients had IBD-dys (2.02%) compared to 29 out of 297 NHWs (9.76%). Adjusting for disease duration, primary sclerosing cholangitis, family history of colon cancer, and smoking, Hispanics had a lower prevalence of IBD-dys compared to NHW [ORadjusted = 0.207 (95% CI 0.046–0.938), P = 0.008].

Conclusions
Hispanics with IBD undergoing surveillance had a lower prevalence of IBD-dys than their NHW counterparts, despite similar risk factors. Future studies should examine dietary and microbial factors that may explain differences in risk.
Methodology and Initial Results From a Real-World Observational Cohort of Patients With Inflammatory Bowel Disease: TARGET-IBD
Authors: Click Benjamin , Barnes Edward L , Cohen Benjamin L , Sands Bruce E , Hanson John S , Regueiro Miguel , Rubin David T , Dubinsky Marla C , Gazis Derek R , Dalfonso Laura , Hildebrand Janet S , Crawford Julie M , Long Millie D 
Published: March 2021

Abstract

Background
Data on care patterns for inflammatory bowel disease (IBD) from large-scale, diverse clinical cohorts in real-world practice are sparse. We developed a real-world cohort of patients receiving care at academic and community sites, for comparative study of therapies and natural history of IBD.

Methods
We describe novel methodology of central abstraction of clinical data into a real-world IBD registry with patient reported outcomes (PROs). Baseline demographics, clinical characteristics, healthcare utilization, and disease metrics were assessed. Bivariate statistics were used to compare demographic and clinical data by Crohn disease (CD) or ulcerative colitis (UC) and site of care (academic, community).

Results
In 1 year, 1343 IBD patients (60.1% CD, 38.9% UC) were recruited from 27 academic (49.5%) and community (50.5%) sites, exceeding expectations (110% enrolled). Most participants also consented to provide PROs (59.5%) or biosamples (85.7%). Overall, 48.7% of the cohort provided a baseline PRO, and 62.6% provided a biosample. Compared to UC, CD subjects had higher prior (34.1% CD vs 7.7% UC; P &lt; 0.001) and current (72.1% vs 47.9%; P &lt; 0.001) biologic utilization. CD participants from academic sites had more complicated disease than those from community sites (62.5% vs 46.8% stricturing/penetrating; 33.5% vs 27% perianal; 36.8% vs 14.5% prior biologic, respectively). Nearly all (90.4%) participants had endoscopic data of whom 37.7% were in remission. One-year retention was 98.4%.

Conclusions
Centralized data abstraction and electronic PRO capture provided efficient recruitment into a large real-world observational cohort. This novel platform provides a resource for clinical outcomes and comparative effectiveness research in IBD.