bluuebunny/crossref_metadata_2025_split huggingface dataset:
Measuring contagion during COVID-19 through volatility spillovers of BRIC countries using diagonal BEKK approach
Authors: Malik Kunjana , Sharma Sakshi , Kaur Manmeet 
Published: February 2021

PurposeThe outbreak of the coronavirus disease 2019 (COVID-19) pandemic is an unprecedented shock to the BRICS (Brazil, Russia, India, China, South Africa) economy and their financial markets have plummeted significantly due to it. This paper adds to the recent literature on contagion due to spillover by uniquely examining the presence of pairwise contagion or volatility transmissions in stock markets returns of India, Brazil, Russia, China and USA prior to and during COVID-19 pandemic period.Design/methodology/approachIn this study, the generalised autoregressive conditional heteroskedasticity (GARCH) by Bollerslev (1986) under diagonal parameterization is used to estimate multivariate GARCH framework also known as BEKK (Baba EngleKraft and Kroner) model on stock market returns of BRIC nations and the US.FindingsThe empirical results show that the model captures the volatility spillovers and display statistical significance for own past mean and volatility with both short- and long-run persistence effects. Own volatility spillovers (Heatwave phenomenon) have been found to be highest for the US, China and Brazil compared to Russia and India. The coefficients indicate persistence of volatility for each country in terms of its own past errors. The highest and long-term spillover effect is found between US and Russia. The results recommend that Russia is least vulnerable to outside shocks. Finally after examining the pairwise results, it is suggested that the BRIC countries stock indices have exhibited volatility spillover due to the COVID-19 pandemic.Research limitations/implicationsThe study may be extended to include other emerging market economies under a dynamic framework.Practical implicationsResearchers and policymakers may draw useful insights on cross-market interdependencies regarding the spillovers in BRIC countries' stock markets. It also helps design international portfolio diversification strategies and in constructing optimal portfolios during COVID and in a post-COVID world.Originality/valueCOVID-19 has been an improbable event in the history of the world which can have a large impact on the financial economies across the emerging countries. This event can be deemed to be informative enough to measure the co-movements of the equity markets amongst cross-country return series, which has not been investigated so far for BRIC nations.
Recognizing service users’ diversity: social identity narratives of British Pakistanis in a mental health context
Authors: Hussain Basharat , Sheikh Abdullah Zafar , Repper Julie , Stickley Theodore , Timmons Stephen , Shah Mahmood Hussain 
Published: February 2021

Purpose
This study aims to investigate how British Pakistani people talk about their social identity, in the context of mental health, and how this shapes their experiences and perceptions of care delivered by the National Health Service, UK.

Design/methodology/approach
Eight narrative interviews were conducted among members of the Pakistani community living in a city in the UK. The data were analyzed using a narrative analysis approach using “social identity” as a theoretical lens.

Findings
Considering Pakistani service users as a single social entity, and responding with generic approaches in meeting their mental health needs, may not be helpful in achieving equitable treatment. Study participants reject a simple conceptualization of race and ethnicity and how a response based upon stereotypes is woefully inadequate. The study revealed that people from one ethnic or national background cannot be assumed to have a fixed social identity.

Originality/value
This study broadens understanding of how people from a single ethnic background may construct and view their social identities markedly different to others from the same ethnic group. This has implications for service providers in understanding how their clients’ social identity is treated and understood in practice.
Topic structure and evolution patterns of documentary heritage preservation and conservation research in China
Authors: Yun Bai , Yue Zhao , Yaolin Zhou 
Published: February 2021

PurposeThis study aims to identify the prominent topics, the distribution and association characteristics of topics and the topic evolutionary trends of Documentary Heritage Preservation and Conservation (DHPAC) research in China.Design/methodology/approachKeywords of relevant papers in China National Knowledge Infrastructure (CNKI) were extracted as the data source in this study. First, frequency and co-occurrence of keywords of the selected papers were obtained by using SATI. Second, co-word network indicators were calculated with the Pajek software. Then, VOSviewer was applied to optimize the visualization of the sub-communities. Finally, a topics evolution map of this research field was implemented by CorTexT.FindingsThe research topics of DHPAC research in China were unbalanced but distinct. Topics of DHPAC research in China possessed inconspicuous orientation and consistency. The core topics had less influence on the overall network. A research system had formed with archival conservation and ancient books conservation as the core research directions. Research in this field had formed four continuous evolutionary paths about ancient books conservation, salvage conservation, archival conservation and archives conservation technology science with topics fusion and differentiation coexisting. Attentions on “ancient books conservation”, “paper relics conservation”, “electronic record”, “digitization”, “minority”, “documents in the republic of China” had increased during the past two decades and new hot topics of DHPAC research kept appearing in China.Originality/valueThis study synthesized and analyzed the research results of DHPAC research in China from a more comprehensive perspective and revealed the topic structure and longitudinal evolution process intuitively with co-word analysis and social network analysis, which can assist researchers to improve research systematization, discover new research directions and seek cooperative research path.
The nexus between the exchange rates and interest rates: evidence from BRIICS economies during the COVID-19 pandemic
Authors: Garg Bhavesh , Prabheesh K.P. 
Published: February 2021

PurposeThis paper aims to investigate whether the interest rate differentials Granger cause expected change in the exchange rate during the COVID-19 period. The study examines if the investors in the international assets and exchange rate markets take advantages of the relevant information obtained during the COVID-19 pandemic.Design/methodology/approachThis paper used daily data ranging from January 31, 2020 to June 30, 2020 and considered BRIICS economies. The study implemented the Toda–Yamamoto’s Granger causality approach to identify the causality between interest rate differentials and exchange rates. For robustness checks, the study used ARLD short-run dynamics to infer causal relations.FindingsOverall, the results indicate that the interest rate differentials improve the predictability of subsequent exchange rate changes in all six BRIICS economies during the COVID-19 period wherein investors are forward-looking. The empirical results pass the robustness checks.Originality/valueThere is a lack of studies exploring the relationship between interest rate differentials and exchange rates in the presence of an unanticipated event such as the current pandemic. To the best of the authors’ knowledge, this is the first study to explore the causal linkages between interest rate differentials and expected change in exchange rates, focusing on the COVID-19 outbreak period.
Securities cross-holding in the Colombian financial system: a topological approach
Authors: León Carlos , Miguélez Javier 
Published: February 2021

Purpose
From a financial stability viewpoint, this paper aims to study cyclical interdependencies arising from the cross-holding of securities in the Colombian financial system.

Design/methodology/approach
Cross-holding of securities in financial systems occurs when two financial institutions hold securities issued by each other or when more than two financial institutions hold securities issued by each other in a circular structure. Securities cross-holding is key for financial stability because of potential contagion arising from cyclical interdependencies in the connective architecture of financial systems. The presence of cyclical interdependencies is studied based on network analysis. The data set is a multilayer network that comprises bonds, certificates of deposit and equity issued and held by Colombian financial institutions from 2016 to 2019.

Findings
Results show that the extent of securities’ cyclical interdependencies is particularly low and stable – even when cross-holding across different types of securities is considered.

Research limitations/implications
The monetary value of exposures and their size with respect to financial institutions’ balance sheets are not considered. Studying the impact on the financial system’s solvency is a compulsory research path.

Practical implications
The network topology suggests that increased potential contagion by cyclical interdependencies and feedback effects from securities cross-holding is rather limited.

Originality/value
To the best of the authors’ knowledge, this is the first time that cyclical interdependencies arising from the securities cross-holding are studied. From a financial stability perspective, the methodology is general and promising for monitoring and analytical purposes.
Commentary on “The experiences of older carers of people with learning disabilities: ‘I just carry on with it’”
Authors: Sunman Jan 
Published: February 2021

Purpose
The purpose of this paper is to provide a commentary on the article by Rachel Forrester-Jones on the experiences of older carers of people with learning disabilities.

Design/methodology/approach
The commentary reflects on the themes identified in the original article, comparing its findings to the lived experiences of those taking part in older carers’ projects in Oxfordshire, England.

Findings
Similar broad themes were identified in both samples. Given these findings, the extent to which matters have changed, since the Valuing People work on older carers is considered.

Originality/value
The paper discusses policy and practice implications to improve the quality of life of older carers and their families and explores how the voice of older carers can be strengthened to enable them to shape practice and policy.
Edoxaban prevented adverse effects including pyrexia and elevation of D‐dimer caused by the combination of BRAF and MEK inhibitors in a patient with BRAF‐mutant melanoma
Authors: Mukai Kei , Kamata Masahiro , Miyazaki Mirei , Nagata Mayumi , Fukaya Saki , Hayashi Kotaro , Fukuyasu Atsuko , Ishikawa Takeko , Ohnishi Takamitsu , Tada Yayoi , Tanaka Takamitsu 
Published: February 2021

AbstractThe combination of BRAF inhibitor and MEK inhibitor is one of the first‐line treatments for unresectable BRAF‐mutant melanoma or as an adjuvant therapy. However, some patients who received the combination of dabrafenib and trametinib (CombiDT) or the combination of encorafenib and binimetinib (CombiEB) had adverse events (AEs) including pyrexia. We herein report a patient with BRAF‐mutated melanoma who repeatedly developed elevated levels of D‐dimer and pyrexia after CombiDT and CombiEB treatments. Moreover, concomitant edoxaban prevented these AEs, enabling the patient to continue receiving CombiEB.
Spatiotemporal patterns of rhizosphere microbiome assembly: From ecological theory to agricultural application
Authors: Munoz‐Ucros Juana , Zwetsloot Marie J. , Cuellar‐Gempeler Catalina , Bauerle Taryn L. 
Published: February 2021

Abstract

There is urgency in optimizing agricultural production in light of climate uncertainty, human population growth and resource limitations. The rhizosphere microbiome is a promising genetic resource, yet it is poorly understood. Additionally, research into rhizosphere microbial community assembly (MCA) lacks a consistent ecological framework that incorporates the dynamics of the occurring interactions.

We explore the ecological principles that guide community establishment as they pertain to the rhizosphere while reviewing relevant research and highlighting the gaps in knowledge.

We propose a conceptual model for studying the rhizosphere, and argue for higher resolution characterizations of the rhizosphere, under a framework of root and microbial traits that will determine its resulting composition. For this, we borrow concepts from ecological theory to chronologically describe MCA as a function of colonization, distribution and succession under changing plant‐imposed filters. We argue that there is a need to consider the temporal and spatial scale of rhizosphere processes in a manner that is relevant to its microbial components.

Finally, we discuss strategies for managing the rhizosphere microbiome for agriculture and the remaining gaps in knowledge that impede their application.

Synthesis and applications. We aim to initiate a comprehensive conversation on ecological processes and plant and microbial traits that affect rhizosphere assembly. Rhizosphere microbiome research is relatively new and highly multidisciplinary. The use of a shared vocabulary and ecological theory will facilitate the development and advances in this discipline.
Flowering fields, organic farming and edge habitats promote diversity of plants and arthropods on arable land
Authors: Gayer Christoph , Berger Jochen , Dieterich Martin , Gallé Róbert , Reidl Konrad , Witty Rosa , Woodcock Ben A. , Batáry Péter 
Published: February 2021

Abstract

Increased farming intensity led to massive declines across multiple farmland taxa. In Europe, measures introduced to counteract these losses include those considered agronomically productive, such as organic farming, as well as those that support no direct production of crops, such as non‐crop flowering fields in conventional farming systems.

We studied biodiversity effects of non‐productive flowering fields managed under conventional farming compared to both an organically managed cereal mono‐crop (organic winter spelt fields) and a flowering mixed‐crop (organic lentil mixed‐crop fields) as well as conventionally managed winter wheat fields, which served as control crop. These four crop‐use types were studied on six sites over 3 years (17 sites in total) to assess their impact on the activity density (cover for plants), species richness and community composition of wild plants, carabids, spiders, butterflies and wild bees.

Species richness of wild plants was highest under organic farming and at field edges when compared to the interior. In the case of carabids and spiders, species richness was highest at the field edges, but there was no difference between the four crop‐use types. In contrast, activity density and species richness of butterflies and wild bees responded only to flowering crop‐use types, showing no edge effects. Arable land cover in 500 m buffer area also affected community composition of all taxa, with the exception of spiders, but had only minor effects on activity densities and species richness.

Synthesis and applications. Our findings underline that there is no single best measure to promote biodiversity on arable land. Instead a mosaic of non‐productive and productive measures such as conventional flowering fields, organic crops and field edge habitats might be more appropriate to support the regional species pool in arable‐dominated landscapes. To support a range of complementary biodiversity‐promoting farming practices, agricultural policy should foster the coordination and collaboration between multiple farmers within the same region by covering additional costs for coordination and prioritizing collaborative schemes.
Age Segregation, Intergenerationality, and Class Monopoly Rent in the Student Housing Submarket
Authors: Revington Nick 
Published: February 2021

AbstractStudentification—the concentration of students within a particular neighbourhood and associated impacts—represents a “generationed” or age‐segregated housing submarket defined by a distinct life course stage. I analyse this submarket through the lens of David Harvey’s concept of class monopoly rent, a critical theory of residential submarkets, drawing on semi‐structured interviews with key informants and students in Waterloo—Canada’s largest private purpose‐built student accommodation market. Planning interventions, real estate strategies, and neighbourhood politics have intertwined to enable the extraction of class monopoly rent from a clearly delineated student housing submarket. I show how studentification, and the age segregation it entails, is produced by and serves to reproduce capitalist urbanisation, illustrating temporal power dynamics of rent. A radical political response to the impacts of studentification on students and other residents alike must therefore adopt an intergenerational perspective that confronts class and life course dimensions of the process simultaneously.
Combination of bis (α‐furancarboxylato) oxovanadium (IV) and metformin improves hepatic steatosis through down‐regulating inflammatory pathways in high‐fat diet‐induced obese C57BL/6J mice
Authors: Liu Quan , Li Linyi , Gao Lihui , Li Caina , Huan Yi , Lei Lei , Cao Hui , Li Ling , Gao Anli , Liu Shuainan , Shen Zhufang 
Published: February 2021

AbstractThe effects of the combination of bis (α‐furancarboxylato) oxovanadium (IV) (BFOV) and metformin (Met) on hepatic steatosis were investigated in high‐fat diet‐induced obese C57BL/6J mice (HFC57 mice) for 6 weeks. Oral glucose tolerance test was performed to evaluate glucose metabolism. Moreover, blood and hepatic biochemical and histological indices were detected. Besides, Affymetrix‐GeneChip analysis and Western blot of the liver were performed. Comparing to the monotherapy group, BFOV + Met showed more effective improvement in glucose metabolism, which decreased the fasting blood glucose, insulin levels and improved insulin sensitivity in HFC57 mice. BFOV + Met significantly decreased serum ALT and AST activities and reduced hepatic triglyceride content and iNOS activities, accompanied by ameliorating intrahepatic fat accumulation and hepatocellular vacuolation. Enhanced hepatic insulin signalling transduction and attenuated inflammation pathway were identified as the major pathways in the BFOV + Met group. BFOV + Met significantly down‐regulated the protein expression levels of MMPs, NF‐κB, iNOS and up‐regulated phosphorylation of AKT and AMPK levels. We concluded that a combination of BFOV and metformin ameliorates hepatic steatosis in HFC57 mice via alleviating hepatic inflammation and enhancing insulin signalling pathway, suggesting that the combination of BFOV and metformin is a potential treatment for hepatic steatosis.
Anti‐inflammatory effects of α7‐nicotinic ACh receptors are exerted through interactions with adenylyl cyclase‐6
Authors: Zhu Simeng , Huang Shiqian , Xia Guofang , Wu Jin , Shen Yan , Wang Ying , Ostrom Rennolds S. , Du Ailian , Shen Chengxing , Xu Congfeng 
Published: February 2021

Background and PurposeNicotinic ACh receptors containing the α7 sub‐unit (α7‐nAChRs) suppress inflammation through a wide range of pathways in immune cells. These receptors are thus potentially involved in a number of inflammatory diseases. However, the detailed mechanisms underlying the anti‐inflammatory effects of α7‐nAChRs remain to be described.Experimental ApproachAnti‐inflammatory effects of α7‐nAChR agonists were assessed in both murine macrophages (RAW 264.7) and bone marrow‐derived macrophages (BMDM), stimulated with LPS, using immunoblotting, RT‐PCR and luciferase reporter assays. The role of adenylyl cyclase‐6 in the degradation of Toll‐like receptor 4 (TLR4) following endocytosis, was explored via overexpression and knockdown. A mouse model of chronic obstructive pulmonary disease (COPD) induced by porcine pancreatic elastase was used to confirm key findings.ResultsAnti‐inflammatory effects of α7‐nAChRs were largely dependent on adenylyl cyclase‐6 activation, as knockdown of adenylyl cyclase‐6 considerably reduced the effects of α7‐nAChR agonists while adenylyl cyclase‐6 overexpression promoted them. We found that α7‐nAChRs and adenylyl cyclase‐6 are co‐localized in lipid rafts of macrophages and directly interact. Activation of adenylyl cyclase‐6 led to increased degradation of TLR4. Administration of the α7‐nAChR agonist PNU‐282987 attenuated pathological and inflammatory end points in a mouse model of COPD.Conclusion and ImplicationsThe α7‐nAChRs inhibit inflammation through activating adenylyl cyclase‐6 and promoting degradation of TLR4. The use of α7‐nAChR agonists may represent a novel therapeutic approach for treating COPD and possibly other inflammatory diseases.
Molecular diversity of dragonflies in three high‐elevation Andean tropical lakes through DNA barcoding
Authors: Chiriboga‐Ortega Rodrigo , Van der Heyden Christine , Sulen Burgos Maria Eugenia , Ortega Sania , Oña Tania , Velarde Elizabeth , Goethals Peter , Alfaro‐Núñez Alonzo 
Published: February 2021

AbstractGenetic and morphological identification of dragonflies' larvae species in three high‐elevation Andean tropical lakes was done using DNA barcoding of the cytochrome oxidase 1 gene (COI). Phylogeny allowed inferring the evolutionary relationships of at least five species (from 74 samples) that belong to two different families within the Odonata order.Abstract in Spanish is available with online material.
Paternal safety of the use of mycophenolic acid in kidney transplant recipients. Results of the EMVARON study
Authors: Martin‐Moreno Paloma L. , Sánchez‐Fructuoso Ana I. , Mazuecos Auxiliadora , Mir Marisa , Lopez‐Lopez Isabel , González‐Rinne Ana , Coca Armando , Valero Rosalía , Ventura Galiano Ana , Ridao Natalia , Toapanta‐Gaibor Nestor G. , Fernández‐Tagarro Ernesto , Cruzado‐Vega Leonidas , Pérez‐Mir Mónica , Jiménez Carlos 
Published: February 2021

AbstractBackgroundThe use of mycophenolic acid (MPA) in women during pregnancy causes an increase in miscarriages and birth defects with a typical embryopathy profile. Although epidemiological data does not suggest a greater risk among the offspring of male kidney transplant recipients, the European Medicines Agency and The Spanish Agency of Medicines and Medical Devices introduced the recommendation of using contraceptive methods.MethodsWe conducted a national retrospective study in 15 Spanish Kidney Transplant Centers to evaluate the frequency of miscarriages and birth defects between the offspring from male kidney transplants recipients. We included 151 males who had fathered 239 offspring, 225 under MPA and 14 without MPA.ResultsThe results of our study showed an incidence of miscarriages in the MPA group of 9.8%, and of birth defects of 4%.ConclusionsWe observed an incidence of miscarriages between the offspring fathered by kidney transplant males under MPA lower than the general population. The incidence of birth defects was similar to the incidence described in other studies and the fact that we did not find the typical embryopathy profile makes it difficult to associate them to the use of MPA. Because of that, we urge the European and Spanish Agencies to reconsider their recommendations for males.
Reisevorbereitungen für Patienten mit Psoriasis unter Immunsuppression
Authors: Stephan Brigitte , Tittelbach Jörg , Bühler Silja 
Published: February 2021

ZusammenfassungMit der Etablierung moderner Systemtherapien bei Psoriasis ist eine umfassende Beratung für Reisen unter Immunmodulation erforderlich. Es sind organisatorische Aspekte bezüglich Transport und Aufbewahrung, klimatische Besonderheiten des Reiselandes und substanzabhängige Risiken bezüglich Infektionen zu beachten. Impfungen und präventive Maßnahmen sollten vor Reisebeginn erfolgen; je nach geltenden aktuellen nationalen Empfehlungen sind Besonderheiten bei Impfungen unter Immunsuppression zu berücksichtigen.