bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the Problems of Periodization and Features of the Russian Enlightenment
Authors: Shirokova M.A. 
Published: January 2021

In connection with the concept of the "new Enlightenment" formulated in the recent anniversary report of the Club of Rome, the author of the article analyzes the phenomenon of the Enlightenment in Russia. The points of view of domestic and foreign researchers on the positive and negative aspects of the Enlightenment, the reasons for the crisis of the "classical" Enlightenment and the need for its renewal are considered. One of the most important problems of the European Enlightenment of the 18th century - the crisis of public morality. The enlighteners borrowed the norms and values of traditional morality from religious consciousness, but sought to combine them with the guidelines for the rationalization and secularization of society and man. In Russia, this trend also took place, but the Russian Enlightenment is characterized by a more expressed axiologism, an orientation towards the mutual complementarity of moral values, scientific knowledge and socio-political progress.
The author also refers to the discussion about the chronological framework of the Russian Enlightenment, highlighting its three stages: Christianization of Ancient Rus; Europeanization of the Russian Empire in the 18th century; the formation of an independent science, culture and philosophy since the 1830s. In addition, the article talks about the dialectical unity and struggle of cultural and civilizational paradigms in the Enlightenment of Russia. It is concluded that the Russian philosophy, created in the polemics of Slavophiles and Westernizers, realized Kant's idea of the essence of Enlightenment -the ability to use one's own mind.
Peranan Wan Akub di Muntok Bangka Abad ke-18
Authors: Yuliarni Yuliarni 
Published: January 2021

The development of Muntok could not be separated from the long historical story of its original name. This research is presented the background of Wan Akub's arrival in Muntok and his role in the government and economy in the 18th century. This study uses historical methods emphasizes on the biographical approach. Wan Akub is the head of government in Muntok who was sent by the Palembang Sultanate as well as the head of tin mining. Some of his policies were to open an irrigation system or help the tin mining process in Muntok as economic resources for the locals. There were various policies that had been made a considerable influence in Muntok. He imported tin miners from Johor and built clay fortresses to reduce ethnic disputes in Muntok as well introduced tin tiban regulations. He also initiated the distribution of tin products as a form of remuneration. In addition, the migration of Wan Akub's relatives from Siantan left for Bangka acquired by new skills in cloth weaving technique called Cual.
Distributed Ledger Technology and the Future of Money and Banking
Authors: Huibers Fred 
Published: January 2021

Abstract
Nakamoto, S. (2008). Bitcoin: A peer-to-peer electronic cash system. https://bitcoin.org/bitcoin.pdf outlined an alternative to the current monetary system in which banks are replaced by a peer-to-peer system to issue and transfer digital money: the Bitcoin. While Bitcoin has attracted a substantial investment volume, the system has not achieved the status of a viable alternative monetary system. However, the distributed ledger technology (DLT) underlying the payment system is being applied successfully by financial institutions and is likely to have important implications for the future of money and banking. In this paper we therefore focus on the most advanced distributed ledger application in the financial industry: R3 Corda. This paper is structured as follows. In the first section, we relate the debate about systems of money creation to the rise of Bitcoin. Next, the development of R3 Corda is discussed and the lessons learned for monetary reform. We conclude with an assessment of the scope and likelihood of monetary reform as a consequence of DLT applications by central banks.
The Informal Sector, the “implicit” Social Contract, the Willingness to Pay Taxes and Tax Compliance in Zimbabwe
Authors: Sebele-Mpofu Favourate Y 
Published: January 2021

Abstract
The growth of the informal sector in African countries has largely been viewed as an escape from regulation and deliberate intention to avoid paying taxes and these views have been widely popularised, ignoring significant details to the disadvantage of realistic tax policy design. Zimbabwe adopted a presumptive tax system for various informal sector categories to enlarge the tax base and increase tax revenues mobilised. However, presumptive taxes have not generated significant revenue. Tax compliance in the informal sector has often been studied from the tax structure design, the deterrence model perspective and capacity limitations without paying adequate attention to tax morale. Tax morale can be denoted through the peer effect of the compliance behaviour of other taxpayers, the fulfilment of the psychological social contract, transparency and accountability in the use of tax revenues as well as stakeholder communication, built on mutual trust and respect. In light of these tax morale dimensions, it is evident that tax compliance can never be divorced from the intrinsic motivation to pay taxes. The inextricable link, between tax evasion, tax compliance and tax morale, motivates this study. While previous studies on tax morale have applied single method research approaches, this study adopted a sequential exploratory mixed method research design, combining both qualitative and quantitative (through the use of document reviews, semi-structured interviews and questionnaires) in order to bring a balanced view. The study found out that tax morale was a strong driver of tax evasion and non-tax compliance in the informal sector.
MiR-203-3p inhibits the oxidative stress, inflammatory responses and apoptosis of mice podocytes induced by high glucose through regulating Sema3A expression
Authors: Chen Jingfu , Xu Qing , Zhang Wei , Zhen YuLan , Cheng Fei , Hua Guo , Lan Jun , Tu Chang 
Published: January 2021

AbstractDiabetic nephropathy (DN) is the most serious long-term microvascular complication of diabetes, which mainly causes podocyte injury. Many studies have shown that microRNAs play a vital role in the development of DN. Studies have shown that miR-203-3p is involved in mesangial cell proliferation and apoptosis of DN mice. Therefore, we speculated that miR-203-3p might be related to the development of DN, but our study does not provide any evidence. In animal experiments, diabetic mice (db/db) were transfected with iR-203-3p overexpression lentiviral vectors (LV-miR-203-3p) and their control (LV-miR-con), with normal mice (db/m) being used as the control. High glucose (HG)-induced podocytes were used to construct a DN cell model in vitro. The expression levels of miR-203-3p, Semaphorin 3A (Sema3A) and inflammatory cytokines were detected by quantitative real-time polymerase chain reaction. Also, serum creatinine and blood urea nitrogen levels were used to evaluate the degree of renal injury in DN mice. Sema3A and apoptosis-related protein levels were assessed by the western blot analysis. Enzyme-linked immunosorbent assay was used to determine the different oxidative stress-related indicators and inflammatory cytokines. Flow cytometry and caspase-3 activity detection were used to analyze the degree of podocyte apoptosis. Our results suggested that the expression of miR-203-3p was lower in DN mice and in HG-induced podocytes. Overexpression of miR-203-3p reduced the body weight, blood glucose and renal injury of DN mice in vivo, as well as relieve the oxidative stress, inflammatory response and apoptosis of HG-induced podocytes in vitro. Functionally, Sema3A was a target of miR-203-3p, and Sema3A overexpression reversed the inhibitory effect of miR-203-3p on HG-induced podocyte injury. Our findings revealed that miR-203-3p alleviated the podocyte injury induced by HG via regulating Sema3A expression, suggesting that miR-203-3p might be a new therapeutic target to improve the progression of DN.
Eichler cohomology and zeros of polynomials associated to derivatives of L-functions
Authors: Diamantis Nikolaos , Rolen Larry 
Published: January 2021

Abstract
In recent years, a number of papers have been devoted to the study of zeros of period polynomials of modular forms. In the present paper, we
study cohomological analogues of the Eichler–Shimura period polynomials corresponding to higher L-derivatives.
We state a general conjecture about the locations of the zeros of the full and odd parts of the polynomials, in analogy with the
existing literature on period polynomials, and we also give numerical evidence that similar results hold for our higher derivative “period polynomials” in the case of cusp forms. The unimodularity of the roots seems to be a very subtle property which is special to our “period polynomials”. This is suggested by numerical experiments on families of perturbed “period polynomials” (Section 5.3) suggested by Zagier.
We prove a special case of our conjecture in the case of Eisenstein series.
Although not much is currently known about derivatives higher than first order ones for general modular forms, celebrated recent work of Yun and Zhang established the analogues of the Gross–Zagier formula for higher L-derivatives in the function field case.
A critical role in their work was played by a notion of “super-positivity”, which, as recently shown by Goldfeld and Huang, holds in infinitely many cases for classical modular forms.
As will be discussed, this is similar to properties which were required by Jin, Ma, Ono, and Soundararajan in their proof of the Riemann Hypothesis for Period Polynomials, thus suggesting a connection between the analytic nature of our conjectures here and the framework of Yun and Zhang.
A novel gene expression test method of minimizing breast cancer risk in reduced cost and time by improving SVM-RFE gene selection method combined with LASSO
Authors: Gupta Madhuri , Gupta Bharat 
Published: January 2021

Abstract
Breast cancer is the leading diseases of death in women. It induces by a genetic mutation in breast cancer cells. Genetic testing has become popular to detect the mutation in genes but test cost is relatively expensive for several patients in developing countries like India. Genetic test takes between 2 and 4 weeks to decide the cancer. The time duration suffers the prognosis of genes because some patients have high rate of cancerous cell growth. In the research work, a cost and time efficient method is proposed to predict the gene expression level on the basis of clinical outcomes of the patient by using machine learning techniques. An improved SVM-RFE_MI gene selection technique is proposed to find the most significant genes related to breast cancer afterward explained variance statistical analysis is applied to extract the genes contain high variance. Least Absolute Shrinkage Selector Operator (LASSO) and Ridge regression techniques are used to predict the gene expression level. The proposed method predicts the expression of significant genes with reduced Root Mean Square Error and acceptable adjusted R-square value. As per the study, analysis of these selected genes is beneficial to diagnose the breast cancer at prior stage in reduced cost and time.
Differentially methylated CpG sites associated with the high-risk group of prostate cancer
Authors: Kobelyatskaya Anastasiya , Pudova Elena , Fedorova Maria , Nyushko Kirill , Alekseev Boris , Kaprin Andrey , Trofimov Dmitry , Sukhikh Gennady , Snezhkina Anastasia , Krasnov George , Razin Sergey , Kudryavtseva Anna 
Published: January 2021

AbstractProstate cancer (PC) is one of the most common and socially significant oncological diseases among men. Bioinformatic analysis of omics data allows identifying molecular genetic changes associated with the disease development, as well as markers of prognosis and response to therapy. Alterations in DNA methylation and histone modification profiles widely occur in malignant tumors. In this study, we analyzed changes in DNA methylation in three groups of PC patients based on data from The Cancer Genome Atlas project (TCGA, https://portal.gdc.cancer.gov): (1) high- and intermediate-risk of the tumor progression, (2) favorable and unfavorable prognoses within the high-risk group, and (3) TMPRSS2-ERG-positive (tumors with TMPRSS2-ERG fusion transcript) and TMPRSS2-ERG-free cases within the high-risk group. We found eight CpG sites (cg07548607, cg13533340, cg16643088, cg18467168, cg23324953, cg23753247, cg25773620, and cg27148952) hypermethylated in the high-risk group compared with the intermediate-risk group of PC. Seven differentially methylated CpG sites (cg00063748, cg06834698, cg18607127, cg25273707, cg01704198, cg02067712, and cg02157224) were associated with unfavorable prognosis within the high-risk group. Six CpG sites (cg01138171, cg14060519, cg19570244, cg24492886, cg25605277, and cg26228280) were hypomethylated in TMPRSS2-ERG-positive PC compared to TMPRSS2-ERG-negative tumors within the high-risk group. The CpG sites were localized, predominantly, in regulatory genome regions belonging to promoters of the following genes: ARHGEF4, C6orf141, C8orf86, CLASP2, CSRNP1, GDA, GSX1, IQSEC1, MYOF, OR10A3, PLCD1, PLEC1, PRDM16, PTAFR, RP11-844P9.2, SCYL3, VPS13D, WT1, and ZSWIM2. For these genes, analysis of differential expression and its correlation with CpG site methylation (β-value level) was also performed. In addition, STK33 and PLCD1 had similar changes in colorectal cancer. As for the CSRNP1, the ARHGEF4, and the WT1 genes, misregulated expression levels were mentioned in lung, liver, pancreatic and androgen-independent prostate cancer. The potential impact of changed methylation on the mRNA level was determined for the CSRNP1, STK33, PLCD1, ARHGEF4, WT1, SCYL3, and VPS13D genes. The above CpG sites could be considered as potential prognostic markers of the high-risk group of PC.
On the BIC for determining the number of control points in B-spline surface approximation in case of correlated observations
Authors: Kermarrec Gaël , Alkhatib Hamza 
Published: January 2021

Abstract
B-spline curves are a linear combination of control points (CP) and B-spline basis functions. They satisfy the strong convex hull property and have a fine and local shape control as changing one CP affects the curve locally, whereas the total number of CP has a more general effect on the control polygon of the spline. Information criteria (IC), such as Akaike IC (AIC) and Bayesian IC (BIC), provide a way to determine an optimal number of CP so that the B-spline approximation fits optimally in a least-squares (LS) sense with scattered and noisy observations. These criteria are based on the log-likelihood of the models and assume often that the error term is independent and identically distributed. This assumption is strong and accounts neither for heteroscedasticity nor for correlations. Thus, such effects have to be considered to avoid under-or overfitting of the observations in the LS adjustment, i.e. bad approximation or noise approximation, respectively. In this contribution, we introduce generalized versions of the BIC derived using the concept of quasi- likelihood estimator (QLE). Our own extensions of the generalized BIC criteria account (i) explicitly for model misspecifications and complexity (ii) and additionally for the correlations of the residuals. To that aim, the correlation model of the residuals is assumed to correspond to a first order autoregressive process AR(1). We apply our general derivations to the specific case of B-spline approximations of curves and surfaces, and couple the information given by the different IC together. Consecutively, a didactical yet simple procedure to interpret the results given by the IC is provided in order to identify an optimal number of parameters to estimate in case of correlated observations. A concrete case study using observations from a bridge scanned with a Terrestrial Laser Scanner (TLS) highlights the proposed procedure.
The Unity of Reason: Kant’s Copernican Presupposition
Authors: Thornton Edward 
Published: January 2021

AbstractIn the controversial Appendix to theTranscendental Dialectic, Kant claims to “complete the critical work of pure reason” [A670/B698] by providing a transcendental deduction of the ideas of pure reason. In order to analyse the role that this Appendix plays in the first Critique, this paper will read the Appendix alongside Kant’s comments in the B-Preface concerning the astronomy of Copernicus. Through an analysis of the nature of Kant and Copernicus’ respective use of presuppositions, and by looking at their respective attempts to unify a science around a single systematic conception of the object of that science, this paper will offer a defence of the fundamental role that Kant’s transcendental deduction of the ideas of pure reason plays in the text.
Three weak solutions for a Neumann elliptic equations involving the p→(x) \vec p\left( x \right) -Laplacian operator
Authors: Ahmed Ahmed , Vall Mohamed Saad Bouh Elemine 
Published: January 2021

AbstractThe aim of this paper is to establish the existence of at least three weak solutions for the following elliptic Neumann problem{-Δp→(x)u+α(x)|u|p0(x)-2u=λf(x,u)inΩ,∑i=1N|∂u∂xi|pi(x)-2∂u∂xiγi=0on∂Ω,\left\{ {\matrix{ { - {\Delta _{\vec p\left( x \right)}}u + \alpha \left( x \right){{\left| u \right|}^{{p_0}\left( x \right) - 2}}u = \lambda f\left( {x,u} \right)} \hfill & {in} \hfill & {\Omega ,} \hfill \cr {\sum\limits_{i = 1}^N {{{\left| {{{\partial u} \over {\partial {x_i}}}} \right|}^{{p_i}\left( x \right) - 2}}{{\partial u} \over {\partial {x_i}}}{\gamma _i} = 0} } \hfill & {on} \hfill & {\partial \Omega ,} \hfill \cr } } \right.in the anisotropic variable exponent Sobolev spacesW1,p→(⋅)(Ω)\vec p\left( \cdot \right)\left( \Omega \right)where λ > 0 andf(x,t) = |t|q(x)−2t− |t|s(x)−2t,x∈ Ω,t∈ 𝕉 andq(·),s(⋅)∈𝒞+(Ω¯)s\left( \cdot \right) \in {\mathcal{C}_ + }\left( {\bar \Omega } \right).
The discourse of the edge: marginal advantage, positioning and linguistic entrepreneurship
Authors: Lo Bianco Joseph 
Published: January 2021

AbstractThis contribution discusses some links between the linguistics and the economics of the spirit of entrepreneurship and entrepreneurialism. Whether it is individuals or various social groupings, or even entire societies, a review of policies promoting self-investment in language ability links to a neoliberal economic and political ethos of competition, advantage, meritocracy, innovation and risk-taking; and thereby instantiates an essentially exchange and profit based understanding of communication. The depth and persistence of policy attaching personal and commodified gain to language merges with moral character judgements. I discuss four Asian studies of linguistic entrepreneurship, extracting common elements and differences, and then discuss the project of Asian engagement and language study in Australia. Applying the lens of linguistic entrepreneurship to Australia’s promotion of Asian languages reveals an entire project of national re-formation to foster integration into Asian regional economic and geopolitical arrangements. Much of this national project has been premised on reformulating core purposes of language study around the advantaging of individuals and the nation within an ethos of market competition. Australia’s ambition of national integration into Asia has achieved national consensus, reversing a long history of repudiation of the nation’s Asian geography, yet there are still persisting ideas of orientalism. This is particularly exposed in relation to how Asian Australians’ language skills are treated. Minority language maintenance of Asian languages has been construed as problematic, while Anglo-Australian learners’ acquisition of key trade languages of Asia is celebrated and admired. One result of this is that a considerable part of Australia’s Asia literacy project is in tension with its avowed aim of multiculturalism, which would value all language skills, those of maintenance as much as those of new learning.
Source of Life or Kiss of Death: Revisiting State-Civil Society Dynamics in India during COVID-19 Pandemic
Authors: Tandon Rajesh , Aravind Ram 
Published: January 2021

Abstract
As COVID-19 spread through India, Civil Society Organizations (CSO)s mobilized resources to support the efforts of the Government by playing the role of an active partner in providing social and economic welfare to the affected population. This paper aims to provide a concise overview of the response of civil society to the pandemic situation at the grassroots and policy level. Further, the authors discuss the paradox in demonstrated efficiency and commitment of civil society, which follows a crackdown on civil society organizations by the state through silencing voices of dissent and regulating the shrinking civic space. The strained relationship between the government and civil society organizations in India is also examined against the backdrop of draconian legislation and policies framed during the time of COVID-19, proscribing debate, review or consultations. In the context of the pandemic and the subsequent phase of recovery, such actions of the Government will have deleterious effects on the relationship of trust between civil society and the state. Through this paper, the authors argue for a more tolerant and co-operative approach to the functions of civil society organizations by the Government, thus effectively reducing mistrust and suspicion in the intentions of the state.
The Syndemics and Structural Violence of the COVID Pandemic: Anthropological Insights on a Crisis
Authors: Singer Merrill , Rylko-Bauer Barbara 
Published: January 2021

AbstractThis paper examines the COVID-19 pandemic in light of two key concepts in medical anthropology: syndemics and structural violence. Following a discussion of the nature of these two concepts, the paper addresses the direct and associated literatures on the syndemic and structural violence features of the COVID pandemic, with a specific focus on: 1) the importance of local socioenvironmental conditions/demographics and disease configurations in creating varying local syndemic expressions; 2) the ways that the pandemic has exposed the grave weaknesses in global health care investment; and 3) how the syndemic nature of the pandemic reveals the rising rate of noncommunicable diseases and their potential for interaction with current and future infectious disease. The paper concludes with a discussion on the role of anthropology in responding to COVID-19 from a syndemics perspective.
“We Speak Pidgin!” – Family Language Policy as the Telling Case for Translanguaging Spaces and Monolingual Ideologies
Authors: Hirsch Tijana , Kayam Orly 
Published: January 2021

AbstractWith the increase in global movement, both temporary (travel and transsettlement) and permanent (e/immigration), traditional conceptions of the linguistic processes rooted largely in the long-term translocation(s) or migrations are revisited through the study of family language policy. The present study of family language policy serves as a telling case (Mitchell, 1984) of (1) translanguaging (Williams, 1994) as a practical theory of language (Li, 2018), describing how the transnational individual experienced the construction of two intergenerational translanguaging spaces (Li, 2011): the family and the community and (2) how the phenomenon of monolingual ideologies infiltrates the translanguaging space of the family to exert its influences toward the standard, in this case the standard Russian dialect. Importance of increased mobility characteristic of contemporary times and the central role of temporality in linguistic processes and their disruptions are discussed in this article.