bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atmospheric conditioning: Airport automation, labour and the COVID‐19 pandemic
Authors: Lin Weiqiang 
Published: September 2021

AbstractThis paper contributes to debates on human–technologies relations and labour geographies. It thinks through how the adoption of automation is mediated by the conditioning effects of atmospheres in space. Taking the occassion of the COVID‐19 pandemic, the paper presents a case of how atmospheres are capable of determining the trajectories of automation, and providing the guiding backdrop for technological (un)development. Drawing on 40 semi‐structured interviews conducted with airport labour in Singapore in 2020 at the height of the COVID‐19 pandemic, the paper offers an analysis of how airport workers variously and viscerally capitulate to, abandon, and/or desire to collaborate with automation, in ways that are both unstable and atmospherically implicated. To the extent that these affective responses have the potential to change the course of technological and labour futures in airport infrastructures, atmospheres — especially those deliberately advocated by the state and airport management — are also a political force to be reckoned with. The paper concludes with a discussion on how a focus on atmospheres can push geographic research on automation in productive and interesting directions. It views automation not just as a collection of abstract artefacts, but projects constantly subject to the conditioning effects of invisible atmospheres.
Exploring the Effectiveness of Providing Structured Design-for-the-Environment Strategies During Conceptual Design
Authors: Ross Donovan , Ferrero Vincenzo , DuPont Bryony 
Published: September 2021

Abstract
The fuzzy front end of engineering design can present a difficult challenge, and as such, recent engineering design research has focused on guiding and influencing the way a designer ideates. Early ideation can be especially difficult when attempting to integrate specific design objectives in product design, called Design for X (DfX). This paper presents two experiments exploring the efficacy of a structured Design for the Environment (DfE) design method called the Guidelines and Regulations for Early design for the Environment (GREEn) Quiz that provides designers with sustainable design knowledge during the conceptual design phase. The GREEn Quiz operates on a web-based platform and queries the designer about their design concepts; an end-of-quiz report provides abstract DfE knowledge to designers. While this abstract knowledge was able to be applied by designers in a former study, we hypothesize that providing targeted, specific design strategies during conceptual design will enable novice designers to better integrate DfE. In this study, we created these DfE strategies, integrated these into the GREEn Quiz, and studied the efficacy of these strategies when presented to designers at both the expert and novice levels. Results suggest that respondents with access to the strategy-based GREEn Quiz produced concepts with evidence of a broader range of sustainable design decisions and higher solution quality scores. This work shows the promise of supplemental DfE methods for concept generation to enable the design of more environmentally sustainable products.
Biosynthesis of Amyl Alcohol From Scenedesmus quadricauda Microalgae for Light Commercial Vehicle Compression Ignition Engine Using Prediction Models
Authors: Jacob Ashwin , Ashok B. 
Published: September 2021

Abstract
Third-generation feedstocks and its constituent biofuels have shown promising results in the light of sustainable production and as a feasible fuel source for internal combustion (IC) engines. Hence, in this study, a third-generation microalgae feedstock (Scenedesmus quadricauda) biomass was cultivated sustainably using an in situ tubular photo bioreactor and raceway pond to synthesize quintet carbon chained amyl alcohol using Ehrlich biosynthetic pathway. On analyzing the synthesized amyl alcohol, a homogenous mixture of a 20% (vol/vol) amyl alcohol-diesel blend showed similarities with conventional diesel in their physio-chemical properties. This potential fuel source was analyzed though systematic experimentation at maximum throttle position condition in a light commercial vehicle compression ignition engine. The conducted experiments were directed by response surface methodology (RSM) coupled with central composite design (CCD) which delivered a set of influential and interactive responses on engine testing. At optimal operating condition, 0.7% rise in brake thermal efficiency (BTE) and an increased specific fuel consumption of 5.6% is reported due to the lower heating value of the biofuel. Furthermore, a 55.8% and 5.4% drop in smoke and carbon monoxide emissions is observed. However, oxides of nitrogen emission increases by 31.7% for biofuel operation as a tradeoff for the improved combustion characteristics achieved.
Anti-Mullerian Hormone (AMH) as a Predictor of Ovarian Response to Clomiphene Citrate in Polycystic Ovarian Syndrome
Authors: Munira Serajoom , Banu Jesmine , Ishrat Shakeela , Shume Mehnaz Mustary , Uddin Muhammad Jasim , Sultana Sabiha 
Published: September 2021

Background: Serum Anti-Mullerian hormone (AMH) levels in women with polycystic ovary syndrome (PCOS) are two- to threefold higher than in ovulatory women with normal ovaries, corresponding to the two- to threefold increase in the number of small follicles in PCOS. The increased AMH has been hypothesized to reduce follicle sensitivity to follicle stimulating hormone (FSH) and estradiol production, thus preventing follicle selection, resulting in follicular arrest at the small antral phase with failure of dominance. Objective: The study was undertaken to test the hypothesis that high AMH level is associated with poor response to ovulation induction in PCOS women. Methods: This was a cross-sectional comparative study of 50 infertile women with PCOS, grouped into those with AMH level <8 ng/mL and those with AMH level [Formula: see text] 8 ng/mL. All participants received an initial dose of 100 mg/day of clomiphene citrate from 2nd to 6th day of menstrual cycle. Ovarian response (follicle size) was assessed by transvaginal monitoring on 12th day of cycle. Results: A total of 50 women were recruited, of which 4 dropped out. Women with AMH [Formula: see text] 8 ng/mL comprised only 23.91% of the PCOS women. AMH and day 12 follicle size had a statistically significant association. Adjusting for other confounding variables in linear, logarithmic, and logistic analysis, serum AMH had significant negative relationship with follicle size (r = 0.511, p < 0.001). AMH was also positively correlated with serum LH, testosterone and negatively correlated with serum follicle stimulating hormone (FSH), serum TSH and BMI. Conclusion: We observed that higher AMH level women had poor response to ovulation induction compared to women with low AMH level.
Inflammation-Induced Metastatic Colonization of the Lung Is Facilitated by Hepatocyte Growth Factor-Secreting Monocyte-Derived Macrophages
Authors: Arif Arif A. , Huang Yu-Hsuan , Freeman Spencer A. , Atif Jawairia , Dean Pamela , Lai Jacqueline C.Y. , Blanchet Marie-Renee , Wiegand Kimberly C. , McNagny Kelly M. , Underhill T. Michael , Gold Michael R. , Johnson Pauline , Roskelley Calvin D. 
Published: September 2021

Abstract

A rate-limiting step for circulating tumor cells to colonize distant organ sites is their ability to locate a microenvironmental niche that supports their survival and growth. This can be achieved by features intrinsic to the tumor cells and/or by the conditioning of a “premetastatic” niche. To determine if pulmonary inflammation promotes the latter, we initiated models for inflammatory asthma, hypersensitivity pneumonitis, or bleomycin-induced sterile inflammation before introducing tumor cells with low metastatic potential into the circulation. All types of inflammation increased the end-stage metastatic burden of the lungs 14 days after tumor cell inoculation without overtly affecting tumor extravasation. Instead, the number and size of early micrometastatic lesions found within the interstitial tissues 96 hours after tumor cell inoculation were increased in the inflamed lungs, coincident with increased tumor cell survival and the presence of nearby inflammation-induced monocyte-derived macrophages (MoDM; CD11b+CD11c+). Remarkably, the adoptive transfer of these MoDM was sufficient to increase lung metastasis in the absence of inflammation. These inflammation-induced MoDM secrete a number of growth factors and cytokines, one of which is hepatocyte growth factor (HGF), that augmented tumor cell survival under conditions of stress in vitro. Importantly, blocking HGF signaling with the cMET inhibitor capmatinib abolished inflammation-induced early micrometastatic lesion formation in vivo. These findings indicate that inflammation-induced MoDM and HGF in particular increase the efficiency of early metastatic colonization in the lung by locally preconditioning the microenvironment.

Implications:
Inflammation preconditions the distant site microenvironment to increase the metastatic potential of tumor cells that arrive there.
Oscillation Modes of Weld Pool in Stationary GTA Welding Using Structure Laser Method
Authors: Wu Xingpei , Huang Jiankang , He Jing , Liu Shien , Liu Guangyin , Fan Ding 
Published: September 2021

AbstractResearchers have recently attempted to monitor pool oscillations using the three-dimensional laser vision method. However, the deficiency of simulation software will result in significant capital expenditure. Both simulations and experiments are performed in this study, and the Bessel equation is used to analyze the oscillation mode of a weld pool. The laser dot matrix images of (0, 1), (1, 1), (2, 1), and (0, 2) oscillation modes at different times are obtained via structured laser optical measurement simulation. The oscillation mode of a stationary gas tungsten arc weld pool is analyzed based on laser dot matrix images obtained from a structure laser experiment. Results show that the simulated laser dot matrix images are consistent with the experiment results. The oscillation mode of the weld pool can be recognized based on the laser dot matrix image. This study not only provides conditions for assessing the penetrating state of a weld pool, but also enable a further understanding of the oscillation mode of a weld pool and the development of more effective observation methods and measurement tools to effectively control and improve welding quality.
Influence of Ultrasonic Surface Rolling Process and Shot Peening on Fretting Fatigue Performance of Ti-6Al-4V
Authors: Wang Ning , Zhu Jinlong , Liu Bai , Zhang Xiancheng , Zhang Jiamin , Tu Shantung 
Published: September 2021

AbstractAt present, there are many studies on the residual stress field and plastic strain field introduced by surface strengthening, which can well hinder the initiation of early fatigue cracks and delay the propagation of fatigue cracks. However, there are few studies on the effects of these key factors on fretting wear. In the paper, shot-peening (SP) and ultrasonic surface rolling process (USRP) were performed on Ti-6Al-4V plate specimens. The surface hardness and residual stresses of the material were tested by vickers indenter and X-ray diffraction residual stress analyzer. Microhardness were measured by HXD-1000MC/CD micro Vickers hardness tester. The effects of different surface strengthening on its fretting fatigue properties were verified by fretting fatigue experiments. The fretting fatigue fracture surface and wear morphology of the specimens were studied and analyzed by means of microscopic observation, and the mechanism of improving fretting fatigue life by surface strengthening process was further explained. After USRP treatment, the surface roughness of Ti-6Al-4V is significantly improved. In addition, the microhardness of the specimen after SP reaches the maximum at 80 μm from the surface, which is about 123% higher than that of the AsR specimen. After USRP, it reaches the maximum at 150 μm from the surface, which is about 128% higher than that of AsR specimen. It is also found that the residual compressive stress of the specimens treated by USRP and SP increases first and then decreases with the depth direction, and the residual stress reaches the maximum on the sub surface. The USRP specimen reaches the maximum value at 0.18 mm, about − 550 MPa, while the SP specimen reaches the maximum value at 0.1 mm, about − 380 MPa. The fretting fatigue life of Ti-6Al-4V effectively improved after USRP and SP. The surface integrity of specimens after USRP is the best, which has deeper residual compressive stress layer and more refined grain. In this paper, a fretting wear device is designed to carry out fretting fatigue experiments on specimens with different surface strengthening.
Is the simple webbed penis a contraindication to circumcision?
Authors: Bawazir Osama Abdullah , Alhallaq Obada Alladh , Albayhani Bashair , Bawazir Abdullah 
Published: September 2021

AbstractBackgroundSurgical correction of the webbed penis is challenging. We presented the safety and feasibility of webbed penis correction for neonates under local anesthesia using a simple principle of leaving equal cylindrical shaft skin.MethodsThis retrospective study included 530 patients who presented for circumcision to three pediatric surgery centers between May 2017 and January 2020. We included male patients aged less than four weeks old who had circumcision with a minimum of 6 months follow-up. We compared patients with normal penile anatomy (n = 451, Group 1) to a simple webbed penis (n = 79, Group 2).ResultsThere were no differences in age and weight between groups. The procedure time was significantly longer in Group 2 (8.05 ± 3.11 vs. 7.48 ± 2.07 min;P = 0.04). There were no differences in bleeding (P = 0.38), redundant foreskin (P > 0.99), need for corrective surgery (P = 0.38), and re-suturing (P = 0.28) between groups. The procedure success was significantly higher in Group 1 (449 (99.56%) vs. 70 (88.6%);P < 0.001). Parents' satisfaction was measured at two weeks with no difference between both groups.ConclusionSimple penoscrotal web is not a contraindication for neonatal circumcision. Circumcision of the penoscrotal web had good esthetic results with comparable outcomes to those with a normal penis without a web.
Proteomics reveals the effects of drought stress on the kernel development and starch formation of waxy maize
Authors: Guo Jian , Qu Lingling , Hu Yifan , Lu Weiping , Lu Dalei 
Published: September 2021

Abstract
Background
Kernel development and starch formation are the primary determinants of maize yield and quality, which are considerably influenced by drought stress. To clarify the response of maize kernel to drought stress, we established well-watered (WW) and water-stressed (WS) conditions at 1–30 days after pollination (dap) on waxy maize (Zea mays L. sinensis Kulesh).

Results
Kernel development, starch accumulation, and activities of starch biosynthetic enzymes were significantly reduced by drought stress. The morphology of starch granules changed, whereas the grain filling rate was accelerated. A comparative proteomics approach was applied to analyze the proteome change in kernels under two treatments at 10 dap and 25 dap. Under the WS conditions, 487 and 465 differentially accumulated proteins (DAPs) were identified at 10 dap and 25 dap, respectively. Drought induced the downregulation of proteins involved in the oxidation–reduction process and oxidoreductase, peroxidase, catalase, glutamine synthetase, abscisic acid stress ripening 1, and lipoxygenase, which might be an important reason for the effect of drought stress on kernel development. Notably, several proteins involved in waxy maize endosperm and starch biosynthesis were upregulated at early-kernel stage under WS conditions, which might have accelerated endosperm development and starch synthesis. Additionally, 17 and 11 common DAPs were sustained in the upregulated and downregulated DAP groups, respectively, at 10 dap and 25 dap. Among these 28 proteins, four maize homologs (i.e., A0A1D6H543, B4FTP0, B6SLJ0, and A0A1D6H5J5) were considered as candidate proteins that affected kernel development and drought stress response by comparing with the rice genome.

Conclusions
The proteomic changes caused by drought were highly correlated with kernel development and starch accumulation, which were closely related to the final yield and quality of waxy maize. Our results provided a foundation for the enhanced understanding of kernel development and starch formation in response to drought stress in waxy maize.
Ileostomy or ileal pouch-anal anastomosis for ulcerative colitis: patient participation and decisional needs
Authors: Cohan Jessica N. , Ozanne Elissa M. , Hofer Rebecca K. , Kelly Yvonne M. , Kata Anna , Larsen Craig , Finlayson Emily 
Published: September 2021

Abstract
Background
Up to 30% of patients with ulcerative colitis will undergo surgery resulting in an ileal pouch-anal anastomosis (IPAA) or permanent end ileostomy (EI). We aimed to understand how patients decide between these two options.

Methods
We performed semi-structured interviews with ulcerative colitis patients who underwent surgery. Areas of questioning included the degree to which patients participated in decision-making, challenges experienced, and suggestions for improving the decision-making process. We analyzed the data using a directed content and thematic approach.

Results
We interviewed 16 patients ranging in age from 28 to 68 years. Nine were male, 10 underwent IPAA, and 6 underwent EI. When it came to participation in decision-making, 11 patients felt independently responsible for decision-making, 3 shared decision-making with the surgeon, and 2 experienced surgeon-led decision-making. Themes regarding challenges during decision-making included lack of support from family, lack of time to discuss options with the surgeon, and the overwhelming complexity of the decision. Themes for ways to improve decision-making included the need for additional information, the desire for peer education, and earlier consultation with a surgeon. Only 3 patients were content with the information used to decide about surgery.

Conclusions
Patients with ulcerative colitis who need surgery largely experience independence when deciding between IPAA and EI, but struggle with inadequate educational information and social support. Patients may benefit from early access to surgeons and peer guidance to enhance independence in decision-making. Preoperative educational materials describing surgical complications and postoperative lifestyle could improve decision-making and facilitate discussions with loved ones.
The association between malaria prevalence and COVID-19 mortality
Authors: Anyanwu Michael U. 
Published: September 2021

Abstract
Background
The number of persons infected with COVID-19 continues to increase with deaths reported daily across the globe. High income countries such as the US, the UK, Italy and Belgium have reported high COVID-19 related deaths but low-and-middle-income countries have recorded fewer deaths despite having poor healthcare system. This study aimed to investigate the association between malaria prevalence and COVID-19 mortality.

Methods
An ecological study was conducted with data from 195 countries. Spearman’s correlation was used to test the association between the population variables and COVID-19 mortality. Generalized linear model with Poisson distribution was used to determine the significant predictors of COVID-19 mortality.

Results
There was a significant positive correlation between median age, life expectancy, 65+ mortality and COVID-19 mortality while malaria prevalence, sex ratio and cardiovascular mortality were negatively correlated with COVID-19 mortality. Malaria prevalence, life expectancy and mortality rate were significant on multivariate regression analysis.

Conclusion
The results of this study support the hypotheses that there are reduced COVID-19 deaths in malaria endemic countries, although the results need to be proved further by clinical trials.
Physical activity and sedentary behaviors (screen time and homework) among overweight or obese adolescents: a cross-sectional observational study in Yazd, Iran
Authors: Hadianfard Ali Mohammad , Mozaffari-Khosravi Hassan , Karandish Majid , Azhdari Maryam 
Published: September 2021

Abstract
Background
The growing number of adolescents who are overweight or obese (OW / OB) is a public concern. The present study was aimed to evaluate physical activity (PA) and sedentary behaviors (SB) (screen time (ST) and homework time (HT)) among Yazd OW/OB adolescents.

Methods
This cross-sectional study was performed among 510 students aged 12-16 in Yazd, Iran. The general information, PA, and SB (ST and HT) were collected by interview based on the WHO standard questionnaire. Anthropometric data were assessed by precise instruments. Daily energy intake (Energy) was obtained from a 7-day food record. Nutritionist 4 software (version I) was run to estimate the energy.

Results
There was a high prevalence of SB > 2h/day (97.6), ST > 2h/day (70.3%), overweight or obesity (40%), abdominal obesity (36.9%), physical inactivity (29.8%) among the students. The younger age (p = 0.014), energy (p < 0.001), no access to the yard (p < 0.001), family size ≤ 2 (p = 0.023), passive transportation, (p = 0.001), the highest school days’ HT (p = 0.033) and SB (p = 0.021), and the highest weekends’ HT among the students were the risk factors for OW/OB. The highest PA level was associated with a lower risk of OW/OB (p < 0.001). The findings were not the same in both sexes. Compared to the normal weight students, OW / OB spent more time on school days and weekdays for ST (P <0.001), HT (P <0.001, P = 0.005) and SB (P <0.001), respectively. OW/OB students showed a higher weekends’ ST (p < 0.001) and lower HT (p = 0.048) than normal-weight students.

Conclusion
The prevalence of SB, ST, OW/OB, and physical inactivity were common. The school days and weekends’ HT, the school days’ SB and HT, age, energy, PA, and access to the yard, family size, and passive transportation were related to the greater chances of OW/OB students. Given that the expansion of online education and self-isolation in a new situation with COVID-19, it seems we will meet the worrying results.
Factor structure and measurement invariance of the Chinese version of the Center for Epidemiological Studies Depression (CES-D) scale among undergraduates and clinical patients
Authors: Niu Lishui , He Jiayue , Cheng Chang , Yi Jinyao , Wang Xiang , Yao Shuqiao 
Published: September 2021

Abstract
Background
The Center for Epidemiologic Studies Depression scale (CESD) was widely used for screening of depressive symptoms. The purpose of the current study was to investigate the factor structure and measurement invariance of the CESD across genders and groups in a sample of Chinese undergraduates and clinical patients.

Methods
Participants included 3093 undergraduates from the Hunan province and 336 patients from psychological clinics. The structure of the CESD scale was analyzed by confirmatory factor analysis (CFA). Multiple sets of CFAs were used to test measurement invariance across genders among undergraduates and clinical patients. Internal consistency reliability was also evaluated.

Results
The five-factor model achieved satisfactory fit (in the undergraduate sample: WLSMVχ2 = 1662.385, df = 160, CFI = 0.973, TLI = 0.968, RMSEA = 0.055; in the clinical patients: WLSMVχ2 = 502.089, df = 160, CFI = 0.962, TLI = 0.955, RMSEA = 0.072). The measurement invariance of the five-factor model across genders was supported fully assuming different degrees of invariance. The CESD also showed acceptable internal consistency.

Conclusion
Due to its sound structure and measurement invariance, the five-factor model of the CESD is best suited for testing in Chinese mainland college students and clinical patients.