bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proton Conductivity of Porous Zirconium‐Organic Frameworks Filled with Protic Ionic Liquid
Authors: Seidler Christopher F. , Wark Michael 
Published: December 2021

AbstractInfiltration of the protic ionic liquid (PIL) triethylammmonium trifluoromethanesulfonate (TEA‐TFA) into the pores of zirconium metal organic‐frameworks (Zr‐MOFs) featuring interpenetrated networks, so‐called PIZOFs, leads to highly proton conducting dry solids. In case of PIZOFs their modular synthesis allows tailoring the environment in the pores via the chemical nature of the side chains at the organic linkers. By infiltration of different PIZOFs with 50 wt % of the PIL, nanocomposites exhibiting high proton conductivity under anhydrous conditions were obtained. The proton conductivity strongly depends on the chemical nature of the PIZOF pores, i.e., the kind of side chains at the linkers. Gas adsorption studies show that the side chains strongly influence the porosity and the hydrophilicity of the PIZOF materials.
Facile Preparation of Chitosan‐modified Mesoporous Titanium Dioxide Film on Fused‐silica Capillary for Selective Enrichment of Phosphopeptides
Authors: Lv Xinyan , Jiao Shihui , Cui Lili , Wei Zhonglin , Wang Boran , Wang Wenwen , Zhang Qi , Tan Yumei , Pang Guangsheng , Feng Shouhua 
Published: December 2021

AbstractChitosan (Cts), a positively charged natural polysaccharide, is employed to functionalize mesoporous titanium dioxide (mTiO2) nanoparticles. The prepared Cts/mTiO2 composite was used as a stationary phase to coat the inner wall of fused‐silica capillary and obtain uniform Cts/mTiO2 film. The Cts/mTiO2 film is applied to detect and enrich phosphopeptides in complex biological samples based on typical in‐tube solid phase microextraction (IT‐SPME) system. This unique Cts/mTiO2 film exhibits excellent enrichment performances of high selectivity (β‐casein and BSA in molar ratio of 1 : 1000), sensitivity (detection limit as low as 40 fmol of β‐casein tryptic digest solution) and high adsorption capacity (124.5 μg mg−1). Meanwhile, the Cts/mTiO2 film possesses preferable reusability and can be reused more than 10 times. These results confirm that the Cts/mTiO2 film possesses potential and satisfactory prospects in phosphoproteomics analysis.
Synthesis of 6‐Aza‐2‐Hydroxyimino‐5‐Methylpyrimidine Nucleosides for Antiviral Evaluation
Authors: Abou‐Elkhair Reham A. I , Du Jinxi , Wasfy Abdalla A. , Khaill Nisrin A. , Maaroof Hend M. , Hassan Marwa H. , Ahmed Ayman S. , Hassan Abdalla E. A. , Sheng Jia 
Published: December 2021

AbstractThe syntheses of a series of novel 6‐aza‐2‐hydroxyimino‐5‐methylpyrimidine and related nucleosides are described. A suitably protected 2‐methylthiopyrimidine nucleoside was selected as the precursor for installing a hydroxyimino moiety at the C‐2 position. The starting nucleobase 6‐aza‐5‐methyl‐2‐thiouracil is prepared in two steps from thiosemicarbazone and ethyl pyruvate. This is subjected to coupling with 1‐O‐acetyl‐2,3,5‐tri‐O‐benzoyl‐β‐D‐ribofuranose under Vorbrüggen glycosylation conditions to provide the corresponding nucleoside in high yield. Activation of the nucleoside to the corresponding 2‐methylthio derivative followed by treatment with hydroxylamine hydrochloride in pyridine provides the corresponding 2‐hydroxyimino derivative in high yield. Finally, the synthesis of five free modified nucleoside analogs is described. The newly synthesized nucleosides have been evaluated against an RNA viral panel and moderate activity was observed against hepatitis C virus, Zika virus, and human respiratory syncytial virus. © 2021 Wiley Periodicals LLC.Basic Protocol 1: Preparation of 6‐aza‐5‐methyl‐2‐thiouracilBasic Protocol 2: Preparation of 6‐aza‐5‐methyl‐2‐thiouridine and 6‐aza‐5‐methyluridineBasic Protocol 3: Preparation of 6‐aza‐2‐hydroxyimino‐5‐methyluridineBasic Protocol 4: Preparation of 6‐aza‐2‐hydroxyimino‐5‐methyl‐4‐thiouridine and 6‐aza‐2‐hydroxyimino‐5‐methylcytosine
Hybrid islanding detection technique for distribution network considering the dynamic behavior of power and load
Authors: Jhuma Umme Kulsum , Mekhilef Saad , Mubin Marizan , Ahmad Shameem , Rawa Muhyaddin , Alturki Yusuf 
Published: December 2021

AbstractNowadays, distributed generation (DG) has become an indispensable part for meeting the growing power demand in electrical power generation and distribution. However, one of the drawbacks of DG is unintentional islanding phenomena, which has become a safety issue for both human and equipment connected to the system. To prevent this hazardous condition, according to IEEE 1547 standards, this islanding condition must be detected within 2 s. This paper proposed an approach to develop a hybrid islanding detection method (IDM) to prevent the damages caused by this islanding condition. The proposed hybrid IDM is a combination of three different IDMs, two passive and one active; that is, rate of change of active power (ROCOAP) and rate of change of reactive power (ROCORP) are passive IDMs where load connecting strategy (LCS) is active. To differentiate islanding conditions with similar occurrences, different case studies are taken into account with photovoltaic (PV) and synchronous generator (SG) working as distributed generators on PSCAD/EMTDC platform. The simulation results confirm that proposed IDM is more favorable compared to other IDMs due to simplicity and fast islanding detection time when its performance is tested on the 11‐kV Malaysian distribution system for various cases.
Negative affect and binge eating: Assessing the unique trajectories of negative affect before and after binge‐eating episodes across eating disorder diagnostic classifications
Authors: Wonderlich Joseph A. , Crosby Ross D. , Engel Scott G. , Crow Scott J. , Peterson Carol B. , Le Grange Daniel , Wonderlich Stephen A. , Fischer Sarah 
Published: December 2021

AbstractObjectiveEcological momentary assessment (EMA) studies suggest that among individuals who binge eat, emotional states and binge eating are functionally related. However, it is unclear whether the trajectory of negative affect (NA) is the same across diagnostic groups or if specific changes in affect are unique to each diagnostic category. This study examined the moderating effect of diagnosis on the trajectory of negative affect before and after binge eating.MethodAdults with eating disorder diagnoses (anorexia nervosa [AN] = 118, bulimia nervosa [BN] = 133, binge‐eating disorder [BED] = 112) completed an EMA where they reported binge eating and negative affect throughout the day. Generalized estimating equation analyses were used to model the trajectories of NA before and after binge eating.ResultsFor all individuals, the linear trajectory of NA significantly increased before (B = 0.044, p < .001) and decreased following the binge‐eating episode (B = −0.054, p < .001). However, diagnosis moderated this trajectory. Specifically, individuals with BN had a greater change in linear trajectories of NA before (B = 2.305, p < .001) and after (B = −4.149, p < .001) binge eating compared to those with BED, but not those with AN. There were no differences in the trajectory of NA between individuals with BED or AN.DiscussionThese findings suggest that binge‐eating episodes in BN may be more strongly associated with NA than in BED, but similar to binge‐eating episodes in AN.
Dancing on the platform: Lability of floral organs of Beilschmiedia appendiculata (Lauraceae)
Authors: Zeng Gang , Liu Bing , Ferguson David K. , Yang Yong 
Published: December 2021

AbstractFloral characters are important for the systematics of the Lauraceae. However, structure and development of the flowers remain poorly known in the family. In this study, we observed the variation and early development of flowers of Beilschmiedia appendiculata, which belongs to the Cryptocarya clade of the family. The results indicate that the shoot apical meristems (SAMs) of the floral buds are enlarged and become a platform for the programmed initiation of the floral organs; floral organs develop basically in an acropetal pattern; phyllotaxis is whorled, initiation of floral primordia within a whorl is asynchronous; floral merosity is extremely variable, for example, dimerous, trimerous, tetramerous, dimerous plus trimerous, and trimerous plus tetramerous. In addition, this species has lost the innermost staminal whorl and glands are not closely associated with stamens of the third staminal whorl, which is unusual in the family Lauraceae. Our new observations broaden our knowledge of the variation of floral structure in Beilschmiedia and pose a fundamental question regarding the ecology underlying the lability of floral organs in B. appendiculata.
Maturity selection but not sowing date enhances soybean productivity and land use in a winter camelina–soybean relay system
Authors: Mohammed Yesuf Assen , Gesch Russ W. , Matthees Heather L. , Wells Samantha S. 
Published: December 2021

AbstractEnhancing crop diversification is needed to ensure sustainable food and energy production in the soybean [Glycine max (L.) Merr.] and maize (Zea mays L.) dominated cropping systems of the US Midwest. Relay‐cropping soybean with winter camelina [Camelina sativa (L.) Crantz] is a means to sustainably intensify food and energy production while adding cropping system diversity. However, soybean yields in relay systems tend to be less than a full‐season monocrop. We hypothesized that improved soybean selection and seeding date for relay cropping could minimize this yield gap, thus increasing agricultural land use productivity. A 2‐year field study was conducted to determine the effects of soybean maturity and seeding date (SD) on winter camelina and soybean yields and land use productivity. Three soybean genotypes differing in maturity (MG) were relayed into winter camelina at rosette (SD1), bolting (SD2), and first flowering (SD3) growth stages. The soybean MGs were MG0.2, MG1.1, and MG1.7 representing early, standard, and late maturity, respectively, for the study region. The MG1.1 sown at SD2 was grown as sole crop check using conventional practices (CP). Results demonstrated that SD3 decreased camelina seed yield compared with SD1 and SD2. Soybean yield in the relay system was greatest for the MG1.7 genotype, and averaged across SD1 and SD2, was just 11.6% less than the sole crop CP check. Relaying soybean MG1.7 at SD2 produced 43% greater total (camelina +soybean) oil yield and greatly improved land use efficiency compared with CP. Appropriate soybean genotype selection can enhance winter camelina–soybean relay system productivity and land use efficiency.
Financially constrained index futures arbitrage
Authors: Glover Kristoffer , Hulley Hardy 
Published: December 2021

AbstractWe develop two models for index futures arbitrage that take the financing constraints faced by real‐world arbitrageurs into account. Our models predict that the price of an index futures contract and the value of its underlying index should deviate further from their theoretical cost‐of‐carry relationship when (a) the contract has a long time to go before expiry, and (b) volatility is high. The fact that these predictions enjoy considerable empirical support highlights the importance of financing constraints for explaining index futures mispricing.
Volatility model applications in China's SSE50 options market
Authors: Chi Yeguang , Hao Wenyan , Zhang Yifei 
Published: December 2021

AbstractWe investigate the effectiveness of various volatility models using China's Shanghai Stock Exchange‐50 (SSE50) Index. Regarding in‐sample fit, the generalized autoregressive conditional heteroscedasticity (GARCH) and the variants of the GARCH model perform much better than the autoregressive conditional heteroscedasticity model. However, we do not observe any significant asymmetric volatility response to past returns in the GJR–GARCH model. For out‐of‐sample forecasting of the future realized volatility, in five of the seven options we investigate, the GARCH volatility forecast outperforms the option implied volatility. We formulate a trading strategy by exploiting the spread between the GARCH volatility forecast and the option implied volatility, and show robust profits when applied to the SSE50 options.
Role of Co species on Co/KIT‐6 catalyst surface in CO2 hydrogenation
Authors: Zhou Guilin , Ai Xing , Tian Yunqi , Huang Rui , Feng Yongcheng , Ren Jianmin 
Published: December 2021

AbstractSupported Co/KIT‐6 catalyst, which has high specific surface area and well‐developed ordered mesoporous structure, was prepared by wet impregnation method. Its physicochemical properties were characterized by transmission electron microscopy (TEM), Brunner–Emmet–Teller (BET), Low‐angle XRD, in situ X‐ray photoelectron spectroscopy (in situ XPS) and H2‐temperature program reduction (H2‐TPR), and its catalytic properties were investigated by CO2 hydrogenation. The in situ XPS and H2‐TPR results indicated that Co oxide species could be reduced by H2 to highly dispersed active metal Co species. The highly dispersed active metal Co species are the main CO2 hydrogenation active centers. CO2 molecules could be reduced by active metal Co species to generate CO molecules and promote CO2 methanation. The prepared Co catalyst presented high CO2 catalytic hydrogenation activities and stability. The CO2 conversion exceeds 47%, and CO and CH4 selectivity reaches 25.6% and 74.4% at 400°C within the range of reaction time of 500 min, respectively. © 2021 Society of Chemical Industry and John Wiley & Sons, Ltd.
A hybrid method combining membrane separation and chemical absorption for flexible CH4refinement and CO2separation in natural gas
Authors: Liu Jian , Kong Chengdong , Zhang Zhongxiao , Yang Liu 
Published: December 2021

AbstractCO2removal is imperative in the sweetening of natural gas. In this work, a hybrid method combining membrane separation and chemical absorption is proposed and applied to test its performances in CH4refinement and CO2separation from natural gas. Specifically, the permeate stream from the membrane separation part was fed into the chemical absorption column. The retentate stream and the chemically scrubbed permeate stream were mixed to produce the final sweetened CH4. Parametric analysis indicates that the enriched CH4volume fraction increases with the growth of feed pressure, but it decreases as the gas flow rate increases. The CO2removal efficiency gets enhanced with the increment of feed pressure, gas temperature and monoethanolamine (MEA) concentration. Under an optimized condition with a feed pressure of 0.9 MPa, a gas flow rate of 40 L/min, a gas temperature of 45°C, a MEA concentration of 15%, and a MEA flow rate of 20 L/h, the high CH4volume fraction of 96.8%, 100% CH4recovery efficiency, and 80.4% CO2removal efficiency can be simultaneously achieved using the hybrid method. Compared with the membrane separation method, the hybrid method has higher CH4recovery efficiency and higher CH4volume fraction, which can meet the requirements of carbon capture utilization and storage (CCUS). Compared with the chemical absorption, the hybrid method consumes less MEA since a part of CO2can be separated by membrane separation. Therefore, the hybrid method is a promising technique for flexible CH4refinement and CO2separation in natural gas. © 2021 Society of Chemical Industry and John Wiley & Sons, Ltd.
Effect of increased alcohol consumption during COVID‐19 pandemic on alcohol‐associated liver disease: A modeling study
Authors: Julien Jovan , Ayer Turgay , Tapper Elliot B. , Barbosa Carolina , Dowd William N. , Chhatwal Jagpreet 
Published: December 2021

Abstract

Background and Aims
Alcohol consumption increased during the COVID‐19 pandemic in 2020 in the United States. We projected the effect of increased alcohol consumption on alcohol‐associated liver disease (ALD) and mortality.

Approach and Results
We extended a previously validated microsimulation model that estimated the short‐ and long‐term effect of increased drinking during the COVID‐19 pandemic in individuals in the United States born between 1920 and 2012. We modeled short‐ and long‐term outcomes of current drinking patterns during COVID‐19 (status quo) using survey data of changes in alcohol consumption in a nationally representative sample between February and November 2020. We compared these outcomes with a counterfactual scenario wherein no COVID‐19 occurs and drinking patterns do not change.
One‐year increase in alcohol consumption during the COVID‐19 pandemic is estimated to result in 8000 (95% uncertainty interval [UI], 7500–8600) additional ALD‐related deaths, 18,700 (95% UI, 17,600–19,900) cases of decompensated cirrhosis, and 1000 (95% UI, 1000–1100) cases of HCC, and 8.9 million disability‐adjusted life years between 2020 and 2040. Between 2020 and 2023, alcohol consumption changes due to COVID‐19 will lead to 100 (100–200) additional deaths and 2800 (2700–2900) additional decompensated cirrhosis cases. A sustained increase in alcohol consumption for more than 1 year could result in additional morbidity and mortality.

Conclusions
A short‐term increase in alcohol consumption during the COVID‐19 pandemic can substantially increase long‐term ALD‐related morbidity and mortality. Our findings highlight the need for individuals and policymakers to make informed decisions to mitigate the impact of high‐risk alcohol drinking in the United States.
Norhygrine Alkaloid and Its Derivatives: Synthetic Approaches and Applications to the Natural Products Synthesis
Authors: Smolobochkin Andrey V. , Gazizov Almir S. , Burilov Alexander R. , Pudovik Michail A. 
Published: December 2021

AbstractThis review summarizes the advances in the synthesis of norhygrine and its derivatives over the past ten years, with special attention paid to stereoselective methods of their preparation. Information on the biological activity of some derivatives of 1‐(pyrrolidin‐2‐yl)propan‐2‐one is presented and the possibility of using pyrrolidines containing a terminal carbonyl group in the synthesis of various alkaloids with useful properties is shown.
A major step in developing Mainland China's cross‐border insolvency law
Authors: Wee Meng Seng 
Published: December 2021

AbstractSection 5 of Mainland China's Enterprise Bankruptcy Law provides that, in the absence of treaties, Chinese courts may recognise foreign insolvency proceedings based on reciprocity. The meaning of reciprocity is very uncertain, and no rules have been laid down on how recognition or assistance may be given to foreign insolvency proceedings. The Mainland has not entered into any treaty or arrangement on the matter with another jurisdiction. On 14 May 2021, the Mainland signed an agreement with Hong Kong, under which the Mainland issued an Opinion on the rules for the recognition of and assistance to Hong Kong insolvency proceedings. This article argues that this is a momentous development for both the Mainland and Hong Kong. It explains how the Opinion adapted provisions and ideas from the UNCITRAL Model Law on Cross‐Border Insolvency with modifications to suit the Mainland's needs and the objectives it wanted to achieve; in particular, the Mainland's concern with mitigating the risks arising from the Opinion's implementation. At the same time, however, cases decided after the coming into force of the arrangement revealed the hurdles posed by the corporate structure that Chinese groups in Hong Kong adopted to the utility of the arrangement, foreshadowing dynamic developments in practice and debate in the doctrinal and theoretical spheres.
Survival outcomes of patients with nonsmall cell lung cancer concomitantly receiving proton pump inhibitors and immune checkpoint inhibitors
Authors: Baek Yeon‐Hee , Kang Eun Joo , Hong Soojung , Park Sohee , Kim Ju Hwan , Shin Ju‐Young 
Published: December 2021

AbstractRecent evidence suggests that gut microbiota dysbiosis adversely affects the efficacy of immune checkpoint inhibitors (ICIs). Our objective was to investigate the association between concomitant use of proton pump inhibitors (PPIs) and ICIs, and poor prognosis in patients with nonsmall cell lung cancer (NSCLC). We conducted a cohort study using a completely enumerated lung cancer cohort from a nationwide healthcare database in South Korea. We identified 2963 patients treated with ICIs as second‐line or later therapy for stage ≥IIIB NSCLC. PPI use was ascertained within 30‐days before and on the date of ICI initiation, and nonuse was defined as no prescription of PPIs during this period. Using national vital statistics in South Korea, we assessed the risk of all‐cause mortality associated with concomitant PPI use through a propensity score‐matched Cox proportional hazard model. Among 1646 patients included after 1:1 propensity score‐matching, concomitant PPI use was associated with a 28% increased risk of all‐cause mortality, compared to nonuse (adjusted hazard ratio [HR] 1.28; 95% confidence intervals [CIs], 1.13‐1.46). We observed an increased risk when we restricted the analysis to new users of PPI (adjusted HR = 1.64; 95% CI = 1.25‐2.17). Subgroup analysis showed that PPI use was associated with high mortality risk among patients with viral hepatitis (adjusted HR = 2.72; 95% CI = 1.54‐4.78; Pinteraction = .048). Our study indicates that PPI use is associated with poor prognosis in NSCLC patients treated with ICIs. Further prospective studies are required to determine the risk‐benefit balance of concomitant use of PPIs and ICIs.
Utility of a multidisciplinary team approach with transanal total mesorectal excision for resection of a large pelvic solitary fibrous tumor
Authors: Tanabe Kenji , Nakanishi Yasukazu , Matsumoto Shunya , Yajima Shugo , Kuroe Takashi , Watanabe Reiko , Arai Yasunori , Iwata Shintaro , Ito Masaaki , Masuda Hitoshi 
Published: December 2021

IntroductionSolitary fibrous tumors require complete surgical resection to avoid recurrence. Large solitary fibrous pelvic tumors are difficult to resect completely with conventional surgical methods. We herein report a case in which a joint surgical approach was required for resection due to the location and size of tumor.Case presentationA 45‐year‐old man had a large solitary fibrous tumor in the pelvis, which extended into the left obturator foramen. The patient underwent tumor resection with vesico‐prostatectomy, transanal total mesorectal excision, and opening of the foramen obturatum. The tumor was grossly resected completely. No recurrence was noted nine months after surgery.ConclusionA multidisciplinary team approach with transanal total mesorectal excision may provide complete resect of large pelvic solitary fibrous tumors.