bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and Validation of Clinical Prediction Models for Surgical Success in Patients With Endometriosis: Protocol for a Mixed Methods Study
Authors: Marlin Nadine , Rivas Carol , Allotey John , Dodds Julie , Horne Andrew , Ball Elizabeth 
Published: April 2021

Background
Endometriosis is a chronic inflammatory condition affecting 6%-10% of women of reproductive age and is defined by the presence of endometrial-like tissue outside the uterus (lesions), commonly affecting the pelvis and ovaries. It is associated with debilitating pelvic pain, infertility, and fatigue and often has devastating effects on the quality of life (QoL). Although it is as common as back pain, it is poorly understood, and treatment and diagnosis are often delayed, leading to unnecessary suffering. Endometriosis has no cure. Surgery is one of several management options. Quantifying the probability of successful surgery is important for guiding clinical decisions and treatment strategies. Factors predicting success through pain reduction after endometriosis surgery have not yet been adequately identified.

Objective
This study aims to determine which women with confirmed endometriosis benefit from surgical improvement in pain and QoL and whether these women could be identified from clinical symptoms measured before laparoscopy.

Methods
First, we will carry out a systematic search and review and, if appropriate, meta-analysis of observational cohort and case-control studies reporting one or more risk factors for endometriosis and postsurgical treatment success. We will search PubMed, Embase, and Cochrane databases from inception without language restrictions and supplement the reference lists by manual searches. Second, we will develop separate clinical prediction models for women with confirmed and suspected diagnoses of endometriosis. A total of three suitable databases have been identified for development and external validation (the MEDAL [ISRCTN13028601] and LUNA [ISRCTN41196151] studies, and the BSGE database), and access has been guaranteed. The models will be developed using a linear regression approach that links candidate factors to outcomes. Third, we will hold 2 stakeholder co-design workshops involving eight clinicians and eight women with endometriosis separately and then bring all 16 participants together. Participants will discuss the implementation, delivery, usefulness, and sustainability of the prediction models. Clinicians will also focus on the ease of use and access to clinical prediction tools.

Results
This project was funded in March 2018 and approved by the Institutional Research Ethics Board in December 2019. At the time of writing, this study was in the data analysis phase, and the results are expected to be available in April 2021.

Conclusions
This study is the first to aim to predict who will benefit most from laparoscopic surgery through the reduction of pain or increased QoL. The models will provide clinicians with robustly developed and externally validated support tools, improving decision making in the diagnosis and treatment of women.

International Registered Report Identifier (IRRID)
DERR1-10.2196/20986
Comparing Single-Page, Multipage, and Conversational Digital Forms in Health Care: Usability Study
Authors: Iftikhar Aleeha , Bond Raymond R , McGilligan Victoria , Leslie Stephen J , Rjoob Khaled , Knoery Charles , Quigg Ciara , Campbell Ryan , Boyd Kyle , McShane Anne , Peace Aaron 
Published: April 2021

Background
Even in the era of digital technology, several hospitals still rely on paper-based forms for data entry for patient admission, triage, drug prescriptions, and procedures. Paper-based forms can be quick and convenient to complete but often at the expense of data quality, completeness, sustainability, and automated data analytics. Digital forms can improve data quality by assisting the user when deciding on the appropriate response to certain data inputs (eg, classifying symptoms). Greater data quality via digital form completion not only helps with auditing, service improvement, and patient record keeping but also helps with novel data science and machine learning research. Although digital forms are becoming more prevalent in health care, there is a lack of empirical best practices and guidelines for their design. The study-based hospital had a definite plan to abolish the paper form; hence, it was not necessary to compare the digital forms with the paper form.

Objective
This study aims to assess the usability of three different interactive forms: a single-page digital form (in which all data input is required on one web page), a multipage digital form, and a conversational digital form (a chatbot).

Methods
The three digital forms were developed as candidates to replace the current paper-based form used to record patient referrals to an interventional cardiology department (Cath-Lab) at Altnagelvin Hospital. We recorded usability data in a counterbalanced usability test (60 usability tests: 20 subjects×3 form usability tests). The usability data included task completion times, System Usability Scale (SUS) scores, User Experience Questionnaire data, and data from a postexperiment questionnaire.

Results
We found that the single-page form outperformed the other two digital forms in almost all usability metrics. The mean SUS score for the single-page form was 76 (SD 15.8; P=.01) when compared with the multipage form, which had a mean score of 67 (SD 17), and the conversational form attained the lowest scores in usability testing and was the least preferred choice of users, with a mean score of 57 (SD 24). An SUS score of >68 was considered above average. The single-page form achieved the least task completion time compared with the other two digital form styles.

Conclusions
In conclusion, the digital single-page form outperformed the other two forms in almost all usability metrics; it had the least task completion time compared with those of the other two digital forms. Moreover, on answering the open-ended question from the final customized postexperiment questionnaire, the single-page form was the preferred choice.
Racial and Ethnic Differences in COVID-19 Outcomes, Stressors, Fear, and Prevention Behaviors Among US Women: Web-Based Cross-sectional Study
Authors: Stockman Jamila K , Wood Brittany A , Anderson Katherine M 
Published: April 2021

Background
In the United States, racial and ethnic minorities are disproportionately affected by COVID-19, with persistent social and structural factors contributing to these disparities. At the intersection of race/ethnicity and gender, women of color may be disadvantaged in terms of COVID-19 outcomes due to their role as essential workers, their higher prevalence of pre-existing conditions, their increased stress and anxiety from the loss of wages and caregiving, and domestic violence.

Objective
The purpose of this study is to examine racial and ethnic differences in the prevalence of COVID-19 outcomes, stressors, fear, and prevention behaviors among adult women residing in the United States.

Methods
Between May and June 2020, women were recruited into the Capturing Women’s Experiences in Outbreak and Pandemic Environments (COPE) Study, a web-based cross-sectional study, using advertisements on Facebook; 491 eligible women completed a self-administered internet-based cross-sectional survey. Descriptive statistics were used to examine racial and ethnic differences (White; Asian; Native Hawaiian or other Pacific Islander; Black; Hispanic, Latina, or Spanish Origin; American Indian or Alaskan Native; multiracial or some other race, ethnicity, or origin) on COVID-19 outcomes, stressors, fear, and prevention behaviors.

Results
Among our sample of women, 16% (73/470) reported COVID-19 symptoms, 22% (18/82) were concerned about possible exposure from the people they knew who tested positive for COVID-19, and 51.4% (227/442) knew where to get tested; yet, only 5.8% (27/469) had been tested. Racial/ethnic differences were observed, with racial/ethnic minority women being less likely to know where to get tested. Significant differences in race/ethnicity were observed for select stressors (food insecurity, not enough money, homeschooling children, unable to have a doctor or telemedicine appointment) and prevention behaviors (handwashing with soap, self-isolation if sick, public glove use, not leaving home for any activities). Although no racial/ethnic differences emerged from the Fear of COVID-19 Scale, significant racial/ethnic differences were observed for some of the individual scale items (eg, being afraid of getting COVID-19, sleep loss, and heart racing due to worrying about COVID-19).

Conclusions
The low prevalence of COVID-19 testing and knowledge of where to get tested indicate a critical need to expand testing for women in the United States, particularly among racial/ethnic minority women. Although the overall prevalence of engagement in prevention behaviors was high, targeted education and promotion of prevention activities are warranted in communities of color, particularly with consideration for stressors and adverse mental health.
Patient Satisfaction and Trust in Telemedicine During the COVID-19 Pandemic: Retrospective Observational Study
Authors: Orrange Sharon , Patel Arpna , Mack Wendy Jean , Cassetta Julia 
Published: April 2021

Background
Los Angeles County is a hub for COVID-19 cases in the United States. Academic health centers rapidly deployed and leveraged telemedicine to permit uninterrupted care of patients. Telemedicine enjoys high patient satisfaction, yet little is known about the level of satisfaction during a crisis and to what extent patient- or visit-related factors and trust play when in-person visits are eliminated.

Objective
The aim of this study is to examine correlates of patients’ satisfaction with a telemedicine visit.

Methods
In this retrospective observational study conducted in our single-institution, urban, academic medical center in Los Angeles, internal medicine patients aged ≥18 years who completed a telemedicine visit between March 10th and April 17th, 2020, were invited for a survey (n=1624). Measures included patient demographics, degree of interpersonal trust in patient-physician relationships (using the Trust in Physician Scale), and visit-related concerns. Statistical analysis used descriptive statistics, Spearman rank-order correlation, and linear and ordinal logistic regression.

Results
Of 1624 telemedicine visits conducted during this period, 368 (22.7%) patients participated in the survey. Across the study, respondents were very satisfied (173/365, 47.4%) or satisfied (n=129, 35.3%) with their telemedicine visit. Higher physician trust was associated with higher patient satisfaction (Spearman correlation r=0.51, P<.001). Visit-related factors with statistically significant correlation with Trust in Physician score were technical issues with the telemedicine visit (r=–0.16), concerns about privacy (r=–0.19), concerns about cost (r=–0.23), satisfaction with telemedicine convenience (r=0.41), and amount of time spent (r=0.47; all P<.01). Visit-related factors associated with patients’ satisfaction included fewer technical issues (P<.001), less concern about privacy (P<.001) or cost (P=.02), and successful face-to-face video (P<.001). The only patient variable with a significant positive association was income and level of trust in physician (r=0.18, P<.001). Younger age was associated with higher satisfaction with the telemedicine visit (P=.005).

Conclusions
There have been calls for redesigning primary care after the COVID-19 pandemic and for the widespread adoption of telemedicine. Patients’ satisfaction with telemedicine during the COVID-19 pandemic is high. Their satisfaction is shaped by the degree of trust in physician and visit-related factors more so than patient factors. This has widespread implications for outpatient practices and further research into visit-related factors and the patient-provider connection over telemedicine is needed.
Interrupting Sitting Time in Postmenopausal Women: Protocol for the Rise for Health Randomized Controlled Trial
Authors: Hartman Sheri J , Dillon Lindsay W , LaCroix Andrea Z , Natarajan Loki , Sears Dorothy D , Owen Neville , Dunstan David W , Sallis James F , Schenk Simon , Allison Matthew , Takemoto Michelle , Herweck Alexandra M , Nguyen Bao , Rosenberg Dori E 
Published: April 2021

Background
Many older adults spend the majority of their waking hours sitting, which increases their risk of chronic diseases. Given the challenges that many older adults face when engaging in moderate-to-vigorous physical activity, understanding the health benefits of decreasing sitting time and increasing the number of sit-to-stand transitions is needed to address this growing public health concern.

Objective
The aim of this 3-arm randomized controlled trial is to investigate how changes in sitting time and brief sit-to-stand transitions impact biomarkers of healthy aging and physical, emotional, and cognitive functioning compared with a healthy attention control arm.

Methods
Sedentary and postmenopausal women (N=405) will be recruited and randomly assigned to 1 of the 3 study conditions for 3 months: healthy living attention control (Healthy Living), reduce sitting time (Reduce Sitting), and increase sit-to-stand transitions (Increase Transitions). Assessments conducted at baseline and 3 months included fasting blood draw, blood pressure, anthropometric measurements, physical functioning, cognitive testing, and 7 days of a thigh-worn accelerometer (activPAL) and a hip-worn accelerometer (ActiGraph). Blood-based biomarkers of healthy aging included those associated with glycemic control (glycated hemoglobin, fasting plasma insulin and glucose, and homeostatic model assessment of insulin resistance).

Results
Recruitment began in May 2018. The intervention is ongoing, with data collection expected to continue through the end of 2022.

Conclusions
The Rise for Health study is designed to test whether 2 different approaches to interrupting sitting time can improve healthy aging in postmenopausal women. Results from this study may inform the development of sedentary behavior guidelines and interventions to reduce sitting time in older adults.

Trial Registration
ClinicalTrials.gov NCT03473145; https://clinicaltrials.gov/ct2/show/NCT03473145

International Registered Report Identifier (IRRID)
DERR1-10.2196/28684
Should I Install LaTeX , MiKTeX or TexStudio?
Authors: Christian Ibiloye Abiodun 
Published: April 2021

In various guises, this is a common question, seemingly innocent, but
actually betraying a fundamental confusion about LaTeX directory, and
the levels of operation in the TeX World; concepts, distributions,
distributions, variants and the TeX family and friends (i.e., users,
contributors, dependent and extended language & softwares). TeX is a
typesetting language developed by Donald E. Kunth, today’s worldwide de
facto standard for high quality document typesetting. LateX is a Tex
based typesetting system and collection of macros for document
compilation and publication - not a word processor. MiKTeX is a compiler
and an Windows O/S based TeX/LaTeX distributions. The purpose of this
read is to clear the confusion and give a comprehensive introduction to
the World of LaTeX, hence provide information and technical bases for
anyone, authors including academias to choose between LaTeX/Tex
distributions to install given the features of the offered LaTeX engines
and Compilers needed by their project or document typesetting. This
fills the gaps in knowledge and literature, aside numerous plagiarized
blogs , confusing articles (as learning latex itself) , confusing
articles (as learning latex itself) and guidelines relating to
scientific typesetting, LaTeX distributions, .tex editors, LaTeX
distributions, .tex editors, Latex2e, LaTeX3 and the the LaTeX family.
PENINGKATAN AKTIVITAS DAN HASIL BELAJAR MATERI SUMBER DAYA ALAM MELALUI MODEL PEMBELAJARAN DIRECT INSTRUCTION
Authors: Ngadilah Ngadilah 
Published: April 2021

Penelitian bertujuan untuk meningkatkan aktivitas dan hasil belajar IPS materi sumber daya alam melalui model pembelajaran Direct Instruction pada siswa kelas IV SD 2 Gondangmanis semester I tahun pelajaran 2017/2018. Prosedur pelaksanaan dan implementasi di lokasi penelitian terbagi dalam dua siklus. Siklus I dilakukan dua kali pertemuan dan begitu juga siklus II dilakukan dua kali pertemuan. Hasil penelitian ini menunjukkan bahwa aktivitas belajar siswa pada siklus I memperoleh rata-rata skor 20,8 atau sebesar 73,45% (cukup baik), siklus II meningkat menjadi 25,4 atau sebesar 90,35% (sangat baik). Pada akhir tindakan siklus I nilai rata-rata yang diperoleh 70,48 atau sebesar 71,43% mengalami peningkatan 20,81% dari kondisi awal. Nilai rata-rata siklus II diperoleh 78,57 atau sebesar 85,71% ketuntasan belajar sehingga mengalami peningkatan sebesar 14,28% dari siklus I. Disimpulkan bahwa penerapan model pembelajaran direct instruction dapat meningkatkan aktivitas dan hasil belajar IPS materi sumber daya alam pada siswa kelas IV SD 2 Gondangmanis Kudus.
Prevalence of Third Molar Agenesis in Patients – A Panoramic Retrospective Study
Authors: Padmanabhan Vivek , Khaled AR Abo Mostafa Omar , Kamel Rahhal Lama M. 
Published: April 2021

Background/Purpose: Agenesis is found to be the most common dental anomaly affecting at least 25% of the population. Agenesis is an anomaly where the tooth germ fails to differentiate completely into dental tissues resulting in congenitally missing teeth. The aim of this study was to determine the prevalence of bilateral agenesis of mandibular second premolars. This study also reflects upon the treatment options available for the agenesis of mandibular second premolars.
Materials and Methods: Bilateral agenesis was considered as agenesis and unilateral agenesis was excluded from the study. Orthopantamograms (OPGs) of 945 dental patients aged 6 years -30 years were examined for the agenesis of teeth. Descriptive statistics were used to describe the percentages and frequencies were calculated using chi square test and the level of significance was considered if p value was <0.05.
Results: The prevalence of bilateral agenesis or congenitally missing mandibular second premolars were at 10.5%.
Conclusions: The prevalence rates of bilateral agenesis or congenitally missing mandibular second premolars are more common in males than females. A well informed evidence based decision should be taken for the clinical management of the missing mandibular second premolars.
EVALUASI PENERAPAN NO.108 AKUNTANSI ASURANSI SYARIAH (STUDI KASUS PADA TAFAKUL KELUARGA BANDA ACEH)
Authors: Zuhra Fitria , Bustamam Bustamam 
Published: April 2021

The purpose of this study was to determine how the suitability of the recognition, measurement, presentation and disclosure of sharia insurance accounting in the tafakul banda aceh family. This researt using descriptive statistical analysis or qualitative method. The data obtained trough a direct interview with Mr.Jamaluddin as head of the the tafakul banda aceh family agency. The result of the study show that from the financial statements they made, they revealed that there were investments in tabarru’ funds, assets, then allowances discussed, financial health, contributions, metc.participants, tabarru’ funds, investment funds,technical allowances allowances, and asset details of this statement are in accordance with item no.108.
ПАРАДИГМАЛЬНИЙ ПІДХІД У ФОРМУВАННІ КОМУНІКАТИВНОЇ КОМПЕТЕНТНОСТІ МАЙБУТНІХ ФАХІВЦІВ ПОЧАТКОВОЇ ШКОЛИ
Authors: Бірюк Людмила , Пішун Сергій 
Published: April 2021

У статті зроблена спроба теоретичного аналізу парадигмального підходу як сукупності ключових положень та ідей, що визнані педагогічною спільнотою в конкретний період і лежать в основі наукових досліджень. Зазначено, що формування освітніх парадигм відбувається в процесі освоєння людством різних способів взаємодії зі світом, тому кожна з них відповідає тому чи тому його сприйняттю як педагогічного об’єкта.
Парадигмальний підхід до розвитку особистості в умовах функціонування освітньої діяльності забезпечує новий перцептивно-комунікативний процес спілкування, причому зв’язки, що виникають, не лише повторюють систему функціональних відносин різних компонентів суспільства, а й взагалі є його найважливішим вираженням у педагогічному дискурсі.
АКТУАЛЬНІ ПРОБЛЕМИ ВАЛЕОЛОГІЧНОГО ВИХОВАННЯ СТУДЕНТІВ В УМОВАХ ЗМІШАНОГО НАВЧАННЯ
Authors: Шупік Ігор 
Published: April 2021

У статті висвітлена проблема збереження здоров’я студентів в умовах змішаного та дистанційного навчання. Описано аналіз досвіду та результати дослідження чинників, які є причиною погіршення стану здоров’я студентів під час організації дистанційного і змішаного навчання.
Зосереджено увагу на шляхах розв’язання завдань валеологічного виховання студентської молоді у закладах вищої освіти, обґрунтовано умови зміцнення здоров’я студентів, та формування у них усвідомлення необхідності дбати про стан здоров’я.
Наголошено на необхідності підтримки і бажання у студентської молоді бути здоровими, а також формування вміння і навичок дотримання здорового способу життя.
АРТ-ПЕДАГОГІЧНІ ТЕХНОЛОГІЇ ЯК ЗАСІБ ФОРМУВАННЯ ТВОРЧОГО САМОВИРАЖЕННЯ УЧНІВ ПОЧАТКОВОЇ ШКОЛИ У ПРОЦЕСІ ПОЗАШКІЛЬНОЇ ОСВІТИ
Authors: Чемоніна Лада , Лесик Анжеліка 
Published: April 2021

Статтю присвячено актуальній проблемі формування творчого самовираження учнів початкової школи у процесі позашкільної освіти засобами арт-педагогічних технологій. Відзначено роль позашкільної освіти як складника безперервної освіти, що покликаний забезпечити розвиток здібностей дітей і молоді у сфері освіти, науки та культури.
Підкреслено ефективність застосування арт-педагогічних технологій у формуванні творчого самовираження учнів у процесі здійснення позашкільної освіти.
Implementing Data Privacy of Cloud Data on a Remote Server using Symmetric Cryptographic Algorithms
Authors: Livingston David , Kirubakaran Ezra , David Eben Priya 
Published: April 2021

Cloud Computing is an excellent technology for Micro Medium and Small Enterprises, which operate under budget shortage for setting up their own Information Technology infrastructure that requires capital investment on resources such as computers, storage and networking devices. Now-a-days, major Cloud Providers like Google and Amazon provide cloud services to its customers for managing their email, contact list, calendar, documents, and their own websites. MSME can take advantage of the cloud-based solutions offered by various Cloud Service Providers for equipping their own employees in doing their day to day activities more effectively and on the cloud. Though cloud computing promotes less expensive and collaborative work environment among a group of employees, it involves risks in keeping the resources such as computing and data secured. Different mechanisms are available for securing the data on the cloud among which encryption of data using cryptographic algorithm is the widely used one. Among various encryption symmetric algorithms, Advanced Encryption Standard is the more secured symmetric encryption algorithm for implementing data privacy on the cloud. In this paper, the authors have discussed some of the issues involved in adopting the cloud in an organization and proposed solutions that will benefit an organization while uploading and managing data in files and databases on the cloud.
Copper–Ligand Cooperativity in H2 Activation Enables the Synthesis of Copper Hydride Complexes
Authors: Aloisi Alicia , Crochet Etienne , Nicolas Emmanuel , Berthet Jean-Claude , Lescot Camille , Thuéry Pierre , Cantat Thibault 
Published: April 2021

Copper(I) complexes of a new participative triphosphane ligand (2H) have been prepared and structurally characterized, in particular [Cu(2H)I] and [Cu(2)]2. Hydrogenation of the latter species afforded the trimetallic hydride species [Cu3(2)2(µ-H)] or in the presence of BEt3, [Cu(2H)(HBEt3)]. Their formation evidences transient formation of [Cu(2H)H] formed by hydrogenolysis of the Cu‒N bond of [Cu(2)]2. [Cu(2H)(HBEt3)] behaves like a hydride complex and inserts CO2 to yield the formate product [Cu(2H)(O2CH)].