bluuebunny/crossref_metadata_2025_split huggingface dataset:
Yogic agnisara increases blood flow in the superior mesenteric artery
Authors: Minvaleev Rinad , Bogdanov Rinat , Bahner David , Levitov Alexander , Kuznetsov Andrej 
Published: June 2021

Abstract
Objectives
Medieval yoga texts claim that a special exercise of the muscles of the anterior abdominal wall, called agnisara, improves digestive function. Main objective of the study was to demonstrate change in the blood flow through superior mesenteric artery (if any) after performance of agnisara.
Design and subjects:
Ultrasound examination of the linear and volumetric indicators of blood flow in the superior mesenteric artery (SMA) before and after performing the agnisara yoga exercise 100 times was carried out in 12 healthy volunteers of both sexes (8 of them women).
Results
A significant increase in the diameter of the SMA, peak systolic and diastolic velocities, and blood flow in the superior mesenteric artery after performing the agnisara exercise 100 times was found, which contrasts with the established data on a decrease in splanchnic blood flow in humans in response to normal physical activity.
Conclusion
Properly performed agnisara increases blood flow to the splanchnic region, registered by the SMA, which should contribute to adequate blood supply to the gastrointestinal tract for successful performance of digestive function.
Effect of Cervical Conization with Positive Margins on Lymph Node Metastasis in Cervical Cancer
Authors: Nagao Yukari , Yokoi Akira , Yoshida Kosuke , Sumi Masanori , Yoshihara Masato , Tamauchi Satoshi , Ikeda Yoshiki , Yoshikawa Nobuhisa , Nishino Kimihiro , Niimi Kaoru , Kajiyama Hiroaki 
Published: June 2021

Abstract
Radical surgery after cervical conization is a common approach for the treatment of cervical cancer. Clinically, rapid disease progression is sometimes observed in patients with positive margins at conization, but the details are unclear. This study aimed to investigate the clinical impact of positive margins at conization in cervical cancer. The medical records of patients with cervical cancer between 2010 and 2020 were reviewed retrospectively and we identified 101 eligible patients who underwent radical hysterectomy, including pelvic lymph node dissection. The association between the positive margins of the conization samples and outcomes, including subsequent lymph node metastasis, was evaluated. The rate of lymphovascular space invasion positivity at radical surgery was significantly higher in patients with positive margins (p = 0.017) than in those with negative margins, although there was no significant difference in the rate of pelvic lymph node metastasis (p = 0.155). Moreover, Kaplan–Meier curves showed that there were no significant difference in overall survival or progression-free survival between the two groups (p = 0.332 and p = 0.200, respectively). A positive margin at conization presented no significant prognostic disadvantage, and therefore, diagnostic conization is one of the reasonable options for locally advanced cervical cancer.
Mapping Microbiome Signatures Associated With Antibiotic Usage On A Swine Production Farm Using Amplicon And Shotgun Data
Authors: Muwonge Adrian , Pollock Jolinda , Barbara Shih , Hutchings Michael R. , Bronsvoort Mark , Mainda Geoffrey , Gally David L. , Corbishley Alexander 
Published: June 2021

Abstract
Background: High antimicrobial usage in swine production has the potential to create reservoirs of antimicrobial resistance (AMR) genes which are transferable to human pathogens via mobile genetic elements. Understanding microbial community responses to antibiotic use is central to unravelling transfer of such resistance genes. Our previous investigation revealed a scenario of optimal antibiotic activity associated with saturation of AMR genes on this farm. Here, we use amplicon and shotgun sequence data to investigate the microbiome signatures that underwrite such a phenomenon.Results: We generated 1.24 and 576 million high quality 16S rRNA gene amplicon and shotgun sequences from 24 porcine faecal samples, respectively. The ratio of taxa detection at genus level between the two methods was 1:24. Using shotgun sequence data, 235 unique AMR genes, 122 modes of action and 17 antibiotic classes were identified using the MEGARes AMR database. Antibiotic usage in growing pigs was significantly associated with microbial and AMR resistome structural and compositional changes detectable two weeks after antibiotic initiation. These were characterised by a down regulation of MDR efflux pumps and an up regulation of macrolide-specific efflux pumps in the growing pigs (treated-group) linked to lower abundance of Verrucomicrobiaeceae. In the sows (non-treated group), a potentially undetected infection, was characterised by a high abundance of pathogenic viral sequences, microbial structural changes i.e. family Alcaligenaceae, and an up regulation of beta-lactamases, including MDR efflux pumps. We assembled 682 near complete bacterial genomes revealing that a large proportion of the resistome is carried by Firmicutes and Proteobacteria, specifically multi-class gene carriage by Clostridium species and Escherichia coli, which occurred exclusively in the treatment group.Conclusion: Microbiome signatures i.e. microbial structure, composition and resistome carriage associated with antibiotic-use can be cost effectively screened with amplicon sequencing but their granularity unravelled using shotgun metagenomic data.
A 10-Year Monitoring of Soil Properties Dynamics and Soil Fertility Evaluation in Chinese Hickory Plantation Regions of Southeastern China
Authors: Jin Jin , Wang Luoqi , Muller Karin , Wu Jiasen , Wang Hailong , Zhao Keli , Berninger Frank , Fu Weijun 
Published: June 2021

Abstract
Long-term monitoring shows intensive management can significantly change soil properties and cause soil degradation. Knowledge related to the spatio-temporal variation of soil properties and their influencing factors are important for nutrient management of economic forest plantation. Here, we conducted an intensive field investigation in Chinese hickory plantation to clarify the spatial and temporal variation of soil properties and its influencing factors, and to evaluate the change of soil fertility. The results showed that the soil pH and soil organic carbon (SOC) significantly increased from 2008 to 2018, while available N significantly decreased from 2008 to 2018. The semi-variance revealed that except available P, the spatial dependencies of soil properties increased from 2008 to 2018. An increasing south-north gradient was found for soil available N, available P, available K and SOC and a decreasing south-north gradient was found for soil pH. One-way ANOVA analysis showed that the change of soil properties from 2008 to 2018 was mainly influenced by anthropogenic factors. The average soil fertility in the whole area was at a medium level from 2008 to 2018. These change of soil properties can provide a reference basis for monitoring the effects of intensive management on soil environment.
Biomechanical Correlation Between Trunk and Foot Kinematics During Golf Swing Movement Before and After Fatigue
Authors: Hakukawa Satoshi , Harato Kengo , Morita Erika , Nishizawa Kohei , Kobayashi Shu , Niki Yasuo , Matsumoto Morio , Nakamura Masaya , Nagura Takeo 
Published: June 2021

Abstract
BackgroundKinematic chain of whole body is important during golf swing. Moreover, it was suggested that kinematics of golf swing was affected by fatigue. The purpose of the present study was to investigate the golf swing before and after fatigue of trunk muscles, and to assess the effect of the fatigue on kinematics of trunk as well as lower extremity. A total of 11 healthy adults participated in the current study. Golf swing motion in each subject was measured with a 7-iron on a grass plate using motion capture system. Three-dimensional kinematics of trunk and lower extremity on the lead side were evaluated.ResultsSagittal trunk instability was observed after fatigue. Regarding the kinematic chain, range of motion of trunk rotation (r = -0.76, p < 0.01) and knee rotation (r = 0.82, p < 0.01) were significantly correlated with the hindfoot rotation before the fatigue task. However, after the fatigue task, the hindfoot rotation was significantly correlated only with the knee rotation (r = 0.76, p <0.01). ConclusionsAs fatigue of trunk muscles will alter swing movement and kinematic chain, trunk muscle training can be one of key strategies to maintain swing performance. Trial registrationOur study was registered to UMIN (No. 000037037, date; 01/07/2019).
Study Solar Energy Usage and Evaluation Activities around Bahir Dar, Ethiopia
Authors: BEZABIH ADDISU WORKU 
Published: June 2021

Abstract
Although solar energy is abundant, accessible, affordable, and ecologically and environmentally friendly, in rural Ethiopia, the majority of Households are still using pollutant kerosene for lighting. The researcher assess factors that influence dissemination activities, like solar PV installation practices, house and institutional system distribution strategies, system failures, and their causes. Additionally, The researcher analyzed the impact of PV orientation, comparing the simulation results currently performed by the PVsyst software with different angles observed during the sphere survey. This made it possible to influence the dissemination activity factors and, therefore, the best orientation. The study also assessed how access to alter, maintenance, lack of public awareness building, institutional problems, tariffs, and lack of a market could affect PV system access and large-scale distribution. To distribute a sufficient amount of solar PV across the country, this study recommends that consideration of distribution impact factors be considered in the most negligible levels to realize maximum results. The PV system could be a tilt at angles of 160 and 00 azimuths; supported by this method, the PV system can collect a mean of 5.36 kW/m2daily, which implies 1929.6 kW/m2/year. This was the vision that the researcher wish to possess a sustainable supply of energy within the country and reduce emissions from biomass.Thus, adapting standard design practices of mathematical formulas, experimental and PVsyst methods through numerical simulation is critical to identifying ways to enhance the efficiency and reliability of stand-alone PV power systems for further practicality within the region.
Functionalized Liposomes Fabrication and Characterization with Erythrocruorin for a Potential Application as a Red Blood Cells Substitute
Authors: García-Flores Nadia , Rodríguez-Beas César , Iñiguez-Palomares Ramón Alfonso , Galván-Moroyoqui José Manuel , Martínez-Soto Juan Manuel , López-Esparza Ricardo , Rodríguez-León Ericka 
Published: June 2021

Aims:
Erythrocruorin is considered for a potential application as a Red Blood Cells Substitute.

Background:
Nanostructured materials such as liposomes and polymeric materials have offered new
alternatives that allow the design of systems as potential substitutes for red blood cells.

Objective:
Functionalized liposomes fabrication and characterization.

Methods:
The liposomes manufactured with egg yolk lecithin prepared by the extrusion method were
functionalized with EfEc and stabilized with polyethylene glycol (PEG) by an absorption method.

Results:
The nanoplatform has a hydrodynamic diameter of 452.4 ± 24.56 nm; this size provides the
ability to avoid problems such as system extravasation, also presents stability (ζ-potential = -30. 06 ±
0.42 mV) and SEM micrographs show a semi-spherical morphology. Also, EfEc showed a peak of
fluorescence emission at 449 nm, which allowed us to observe the protein's presence on the surface
of the liposomes employing CLSM.

Conclusion:
In this work, we report the fabrication and characterization of liposomes with EfEc and
PEG on their surface. The nanoplatform exhibits physical-chemical characteristics that confer a potential
application as a substitute for red blood cells.
Assessment of functional balance in children with sensory impairments undergoing hippotherapy
Authors: Lage Janaine Brandão , Silva Lorena Fuchs , Borges Marilia Carvalho , Nascentes Gabriel Nogueira , Ferreira Isabella Cecílio Resende , Teixeira Vicente de Paula Antunes , Espindula Ana Paula 
Published: June 2021

Objective: To evaluate the functional balance of children with sensory impairments submitted to hippotherapy. Methods: 24 children of both genres equally participated in three groups: cerebral palsy (CP), Down syndrome (DS), and intellectual disability (ID) with the respective age groups (10.71 ± 2.69 years), (12.83 ± 2.64 years), and (11 ± 1.69 years).There were 15 attendances in hippotherapy with riding materials specific to each group. The Pediatric Balance Scale (EEP) was used before the 1st and after the 15th hippotherapy session (pre and post moments) to assess functional balance. The data were analyzed using the Shapiro-Wilk tests (normality), Bartlett test (homogeneity), and, between the pre- and post-care times, the paired t-test (intra-groups) and ANOVA with Bonferroni's multiple comparison tests (between groups), with statistical significance for p < 0.05. Results: in the post-attendance, there was an increase in the EEP score for the three groups (intra groups) with significance for children with ID (p = 0.003) and DS (p = 0.033); the CP group had a lower score (inter groups) in both times, pre (p = 0.003) and post (p = 0.002) attendance. Conclusion: hippotherapy contributed to the functional balance of children with distinct sensory impairments, according to the clinical diagnosis and riding material specific to the group, thus being able to be considered a therapeutic method with relevant benefits regarding the sensory aspects of the population.
Support provided by healthcare professionals to the mothers of newborns in the neonatal unit
Authors: Giroux Suziane de Souza , Dias Brenda Tuany Pacheco , Silva Emanuele Rocha da , Reis Jéssica Haline Souza dos , Lopes Alves Samuel Filipe , Cunha Katiane da Costa , Chermont Aurimery Gomes 
Published: June 2021

Objective: To evaluate the support offered by health professionals to mothers of newborns admitted to the neonatal unit.Methods: Descriptive cross-sectional study with a quantitative approach conducted at the Regional Hospital of Tucuruí, in the state of Pará, region of the Brazilian Amazon, where 33 mothers who had newborn children admitted to the neonatal unit responded to the structured adapted version of the NPST (Nurse Parent Support Tool ). Results: Most were aged 20-34 years (48%), married or in a stable relationship (69%), multiracial (87%), housewife (57%), with up to 11 years of study (72%). The scores for the NPST subdomains were 3.39 ± 1.65 (Communication and Information Support), 4.13 ± 1.33 (Emotional Support), 3.93 ± 1.46 (Incentive Support), and 4.21 ± 1,27 (Instrumental Support). The findings revealed unsatisfactory communication and information support from health professionals to mothers, although they expressed satisfaction with the care provided. Conclusions: The perception of scarcity of human resources and health education, verified in this study, weakens the communication process during hospitalization and influences the mother's well-being, leading to a decrease in the efficiency of the support provided. The improvement in this area can lead to better results in daily practice. The replication of this study to other locations can lead to more significant assistance to mothers of hospitalized neonates and provide new technologies and strategies in health education.
Adapting Chinese Qigong Mind-Body Exercise for Healthy Aging in Older Community-Dwelling Low-income Latino Adults: Pilot Feasibility Study
Authors: Yin Zenong , Martinez Cristina E , Li Shiyu , Martinez Martha , Peng Kezhi , Land William M , Ullevig Sarah L , Cantu Adelita , Falk Sharon , Hernández Arthur E , Ortega Catherine , Parra-Medina Deborah , Simmonds Maureen J 
Published: June 2021

Background
Research translating the evidence for the benefit of mind-body exercise in older Latinos with limited access to community-based healthy aging programs is sparse.

Objective
This study aimed to evaluate the feasibility of Function Improvement Exercises for Older Sedentary Community-Dwelling Latino Residents (FITxOlder), a Community Health Worker (CHW)-led, mobile technology-facilitated Chinese Qigong mind-body exercise program for healthy aging and to explore its impact on physical and cognitive function and quality of life (QoL) in older community-dwelling low-income Latino adults.

Methods
This study was designed as a Stage 1 feasibility study to develop and pilot-test FITxOlder. In Phase 1 (Stage 1A), a working group of seniors, CHWs, and senior center staff guided the adaptation of Chinese Qigong into a healthy aging program. In Phase 2 (Stage 1B), 49 older Latino adults participated in a 3-arm controlled study to test the feasibility and preliminary effect of CHW-led FITxOlder on physical and cognitive function and QoL measures over 16 weeks.

Results
Although the COVID-19 pandemic disrupted the implementation of the study protocol, we found favorable results regarding participant recruitment, retention, and fidelity of implementation. Notable findings included an 89.3% participant retention, 79.4% of the participants completed at least 70% of the weekly exercise goal, and no report of adverse events. The effects on intervention outcome measures were modest.

Conclusions
FITxOlder is feasible for promoting healthy aging in older Latino adults; future research needs to compare its feasibility with other low-impact exercise programs for healthy aging using a randomized controlled trial.

Trial Registration
ClinicalTrials.gov NCT04284137; https://clinicaltrials.gov/ct2/show/NCT04284137
Pirkuma līguma objekta izpratne jauno patērētāju pirkuma direktīvu gaismā
Authors:   Latvijas Universitātes Juridiskā fakultāte, Kārkliņš Jānis 
Published: June 2021

One of the objectives of the European Union is to create an internal market in which the free movement of goods and services is ensured. At the same time, by ensuring the free movement of goods and services, the European Union has a duty to promote a high level of consumer protection. In order to achieve both of these goals at the same time, the European Union has adopted, among other things, a significant number of directives, which the Latvian legislator has mostly transposed into the Consumer Rights Protection Law. Nevertheless, the development of digital technologies has made it necessary to lay down special rules in the event that the subject of the contract contains digital elements. Taking into account the above, this article provides analysis of the content of the new consumer sales directives (2019/770, 2019/771), their implementa­tion as much as possible in connection with the existing Latvian legal system, as well as views some legal issues related to the implementation of directives in Latvia.
Digitālā satura vai digitālā pakalpojuma atbilstības līgumam izpratne patērētāja digitālā pirkuma direktīvā (Direktīvā 2019/770)
Authors:   Latvijas Universitātes Juridiskā fakultāte, Mantrovs Vadims 
Published: June 2021

The present article deals with conformity of a digital content or a digital service with the contract within the recently adopted Consumer Digital Sale Directive (Directive 2019/770) by discussing this issue within the transposition procedure of that directive in Latvia. At the beginning, the article provides a general overview of regulation for conformity with the contract within the framework of the Consumer Digital Sale Directive regarding a digital content or a digital service by discussing main features of this regulation. Furthermore, the article examines subjective and objective grounds for conformity of a digital content or a digital service with the contract in conjuncture with the draft act for transposition of this directive into the Latvian Consumer Rights Protection Act. By establishing incompliances between the directive and the draft act, the article goes on by suggesting legislative proposals for the Latvian legislator to bring the draft act in line with the directive. The article finishes with the conclusion by summarising the discussion reflected in the article and emphasising the legislative proposals for elimination discrepancy between the Consumer Digital Sale Directive and the draft act concerning the regulation of conformity of a digital content or a digital service with the contract.
Videokonferenču izmantošanas perspektīvas valsts pārvaldes un privātpersonu saziņā
Authors:   Latvijas Universitātes Juridiskā fakultāte, Danovskis Edvīns 
Published: June 2021

The article analyses the legal regulation of videocall use in administrative pro­ce­dure, administrative offence procedure and other legally relevant communication between the government and private persons. The context of this analysis is the COVID-19 pandemics, which was the reason to cease in-person customer service in many government institutions. The article provides legal preconditions to create a multifunctional on-line platform, which could offer clients of government institutions customer service that is equivalent to in-person service.
Gender Equal Access to Goods and Services
Authors:   Latvijas Universitātes Juridiskā fakultāte, Dupate Kristīne 
Published: June 2021

Direktīva 2004/113/EK, kura prasa nodrošināt sievietēm un vīriešiem vienlīdzīgu piekļuvi precēm un pakalpojumiem, tika pieņemta 2004. gadā. Tā bija jāievieš līdz 2007. gada 21. decembrim. Neskatoties uz to, ka ir pagājuši jau 13 gadi, kopš dzimumvienlīdzīgai piekļuvei precēm un pakalpojumiem bija jādarbojas praksē, līdztiesība šajā jomā gana bieži netiek nodrošināta. Tas skaidrojams ar to, ka līdz šim nav bijis izvērstākas diskusijas par līdztiesību šajā jomā ne no atbildīgo institūciju puses, nedz arī plašākā sabiedrībā, līdz ar to ievērojama daļa preču pārdevēju un pakalpojumu sniedzēju par šo tiesisko regulējumu neko nezina. Lai pievērtu uzmanību jautājumam par dzimumlīdztiesīgu piekļuvi precēm un pakalpojumiem un šo tiesību nodrošināšanu praksē, šajā rakstā autore pievēršas, pirmkārt, Direktīvas 2004/113/EK materiālā un personālā tvēruma un galveno jēdzienu skaidrošanai, otrkārt, problēmām, kuras saistītas ar šo tiesību nodrošināšanu praksē, un, treškārt, analizē šīs direktīvas normu ieviešanu Latvijas tiesiskajā regulējumā. Autore secina, ka Direktīva 2004/113/EK Latvijā nav ieviesta pilnīgi, jo tiesiskais regulējums neietver tās privātās personas, kuras piedāvā preces un pakalpojumus ārpus savas profesionālās darbības jomas. Turklāt apdrošināšanas jomā nav skaidrs, vai visās apdrošināšanas polisēs būtu obligāti iekļaujami riski, kuri saistīti ar grūtniecību un maternitāti. Ir apšaubāmi, vai, nenodrošinot nevienu šo tiesību ievērošanas administratīvās kontroles mehānismu, tiek ievērots ES tiesību aizsardzības līdzekļu efektivitātes princips.
Kā izturēt Uber testu. EST secinājumi lietā C-62/19 Star Taxi App
Authors:   Latvijas Universitātes Juridiskā fakultāte, Kalniņa Vija 
Published: June 2021

The controversial Uber test has been applied once again. The CJEU judgment in the case C62/19 Star Taxi App acknowledges that the test is applicable and correct in its current form and no changes or improvements can be expected at least for now. In the meantime, the judgment gives one more example on how the Uber test can be executed and what are the preconditions for passing this test successfully. However, one of the most significant aspects that could affect the outcome of this test, that is, whether the factors of the Uber test are cumulative or alternative, remains unclear.