bluuebunny/crossref_metadata_2025_split huggingface dataset:
Test of an innovative method to prepare coffee powder puck, improving espresso extraction reliability
Authors: Angeloni Giulia , Guerrini Lorenzo , Masella Piernicola , Dionisio Andrea , Gatti Riccardo , Parenti Alessandro 
Published: September 2021

AbstractCoffee powder is obtained with a grinding machine. Espresso coffee is prepared when hot water is forced under pressure through the puck of coffee powder, and the optimal espresso flow rate is 1 g s−1. However, this flow rate can change for different extractions, forcing baristas to frequently change the setup of the grinder. Grinding grade is one of the most important sources of variation in the quality of espresso. This study tests an innovative method to prepare coffee powder puck, designed to reduce variability in flow rate between extractions. The method is based on stratified layers of ground coffee with different granulometry, and it was tested in three trials with different coffees and grinders. The flow rate associated with the new method (Patent WO/2020/148258- PCT/EP2020/050773) was more stable than the rate in a conventional system, reliability was optimized by placing larger coffee particles at the bottom, and finer particles at the top of the filter basket.
Kcnk3, Ggta1, and Gpr84 are involved in hyperbaric oxygenation preconditioning protection on cerebral ischemia–reperfusion injury
Authors: Yang Chunhui , Ding Minjun , Shao Guiqiang , Jia Shengjie , Yin Xue , Cui Yuhui , Wang Zetian , Wu Chunrong 
Published: September 2021

AbstractThe present study aimed to explore the potential mechanism of the effect of hyperbaric oxygenation (HBO) preconditioning on cerebral ischemia and reperfusion injury (CIRI). GSE23160 dataset was used to identify differentially expressed genes (DEGs) from striatum between the middle cerebral artery occlusion (MCAO)/reperfusion and sham rats. The gene clusters with continuous increase and decrease were identified by soft clustering analysis in Mfuzz, and functional enrichment analysis of these genes was performed using clusterProfiler package. The intersection set of the genes with significantly altered expression at post-reperfusion 2, 8, and 24 h were screened in comparison to 0 h (sham group), and the expression of these genes was detected in the MCAO/reperfusion model and HBO preconditioning groups by real-time PCR (RT-PCR) and western blotting. A total of 41 upregulated DEGs, and 7 downregulated DEGs were detected, among which the expression of Gpr84 and Ggta1 was significantly upregulated at each reperfusion phase as compared to the sham group, while the expression of Kcnk3 was significantly downregulated except in the postreperfusion 8 h in the striatum group. RT-PCR and western blotting analyses showed that the expression of Ggta1, Gpr84, and Kcnk3 genes between the MCAO/reperfusion and sham rats were consistent with the bioinformatics analysis. In addition, the HBO preconditioning reduced the expression of Ggta1 and Gpr84 and increased the expression of Kcnk3 in MCAO/reperfusion rats. Kcnk3, Ggta1, and Gpr84 may play a major role in HBO-mediated protection of the brain against CIRI.
Meniscus position and size in knees with versus without structural knee osteoarthritis progression: data from the osteoarthritis initiative
Authors: Sharma Kalpana , Eckstein Felix , Wirth Wolfgang , Emmanuel Katja 
Published: September 2021

Abstract
Objective
To explore whether and which quantitative 3D measures of medial and/or lateral meniscus position and size are associated with subsequent medial femorotibial structural progression of knee osteoarthritis and to determine the correlation between central slice and total meniscus measures.

Materials and Methods
Knees with radiographic osteoarthritis from Osteoarthritis Initiative participants with longitudinal medial MRI-based cartilage thickness and radiographic joint space width (JSW) loss over 12 months were selected. These 37 structural progressor knees (64.7 ± 8.0y, 30.2 ± 4.6 kg/m2, 35% men) were matched 1:1 to 37 non-progressor knees (64.6 ± 9.8y, 30.2 ± 4.4 kg/m2, 35% men) without cartilage thickness or JSW loss. Quantitative measures of meniscus position and size were computed from manual segmentations of coronal baseline MRIs. Cohen’s D was used as measure of effect size.

Results
Maximum extrusion distance of the total medial meniscus and mean extrusion in the central 5 and in the central slice were greater for progressor than non-progressor knees (Cohen’s D 0.58–0.66). No significant differences were observed for medial tibial coverage or mean extrusion (entire meniscus). Among medial meniscus morphology measures, only mean height differed between progressor vs non-progressor knees (Cohen’s D 0.40). Among lateral meniscus measures, height and volume were greater in progressor vs. non-progressor knees (Cohen’s D 0.46–0.83). Mean extrusion measures were highly correlated between the entire meniscus and the central (r = 0.88) or the central 5 (r = 0.93) slices.

Conclusions
3D maximum and central medial meniscus extrusion may serve as predictors for subsequent structural progression. Central meniscus extrusion measures could substitute 3D extrusion measurement across the entire meniscus.
Long‐term Outcomes After Lung Cancer Resection in Smokers: Analysis of the National Lung Screening Trial
Authors: Sesti Joanna , Decker Jonathan , Bell Jaimie , Nguyen Andrew , Lackey Adam , Turner Amber L. , Hilden Patrick , Paul Subroto 
Published: September 2021

AbstractBackgroundSmoking is a known risk factor for perioperative complications after lung resection; however, little data exists looking at the impact of smoking status (current versus former) on long‐term oncologic outcomes after lung cancer surgery. We sought to compare overall survival (OS), progression‐free survival (PFS), and cancer‐specific mortality (CSM) in current and former smokers using data from the National Lung Screening Trial (NLST). Additionally, we performed subset analysis in current smokers in order to evaluate the effect of modern surgical techniques on long‐term outcomes.MethodsPatients with clinical stage IA or IB NSCLC who underwent upfront resection within 180 days of diagnosis were identified in the NLST database. Cox proportional hazard regression models were used to assess differences in patient and treatment characteristics with respect to OS and PFS, with a cause‐specific hazard model used for CSM.ResultsA total of 593 patients were included in the study (269 former smokers, 324 current smokers). Lobar resection (LR) was performed more often than sublobar resection (SLR) (481 vs. 112), and thoracotomy was performed more often than thoracoscopy (482 vs. 86). Comparison of current versus former smokers showed no difference in OS or PFS after resection. Higher CSM was seen in current smokers (p = 0.049). Subset analysis of current smokers revealed no difference in OS or PFS between sub‐lobar and lobar resection or thoracotomy and thoracoscopy. Although higher CSM was associated with thoracoscopy versus thoracotomy in this group, this finding was limited by a relatively small thoracoscopy sample size of 44 patients (p = 0.026).ConclusionOur analysis of the NLST database shows no significant difference in OS and PFS when comparing current and former smokers undergoing resection for stage I NSCLC. Active smoking status was associated with higher CSM. Subset analysis of current smokers showed no difference in OS or PFS between sub‐lobar and lobar resection or thoracotomy and thoracoscopy. Higher CSM was seen in current smokers who underwent thoracoscopy compared to thoracotomy; however, this finding was limited by a small sample size.
Akut symptomatische epileptische Anfälle in Assoziation mit COVID-19
Authors: Mauritz Matthias , Trinka Eugen 
Published: September 2021

ZusammenfassungAkut symptomatische epileptische Anfälle treten in einem engen zeitlichen Zusammenhang zu einer akuten strukturellen oder funktionellen Schädigung des Gehirns auf, die viele verschiedene Ursachen haben kann. Neurologische Symptome wie Enzephalopathie, Geruchsstörung und Kopfschmerzen finden sich häufig bei COVID-19. Epileptische Anfälle ereignen sich nur in 1–2 % aller mit COVID-19 hospitalisierten Patient*innen. Eine mögliche direkte Invasion des ZNS durch SARS-CoV‑2 sowie indirekte Effekte durch Hypoxie, Inflammation und metabolische Entgleisungen werden als Ursache für die neurologischen Manifestationen bei COVID-19 angenommen.
Where is Waldo? or find the platelet
Authors: Menter D. G. 
Published: September 2021

AbstractPlatelets evolved from nucleated thrombocytes that exhibit both coagulation and immune function. The essential role of platelets in coagulation is common knowledge. The larger and critical role of platelets in immune responses and cancer are frequently overlooked in our modern-day, large-data-set, sequencing-oriented efforts. Much like Waldo, their small size, biophysical characteristics, rapid biological responses, active cytoskeleton, migration capacity, and lack of a nucleus make them difficult to track as single platelets disappear while executing their function into the histologic “tissue scape”. The adaptive evolution of platelets is linked to placentalization and stopping massive blood loss. This resulted in exclusion of any platelet nucleus and therefore sustainable gene expression due to being extruded in the billions (1011) per day from megakaryocytes under bone marrow protection. The platelets’ small size and sheer number in circulation, combined with an active open canalicular exchange- and membrane-reserve system, plus an array of pathogen receptors enable them to deal with small pathogenic viral treats and to decorate larger ones for further immune identification and immune-cell recruitment. Once stimulated, platelets release most serum-based cytokines and growth factors that contribute to cell growth and wound repair, and potentially to immune suppression. From a self-taught practitioner of the illustrative arts with a ken for platelet biology, this offering is a humble attempt to provide a stimulating sketch of the critical importance of platelet biology and insights into potential new directions for finding the Waldo-esque platelet.
Do agri-food market incentives improve food security and nutrition indicators? a microsimulation evaluation for Kenya
Authors: Ramos María Priscila , Custodio Estefanía , Jiménez Sofía , Mainar-Causapé Alfredo J. , Boulanger Pierre , Ferrari Emanuele 
Published: September 2021

AbstractThe sustainable development goal #2 aims at ending hunger and malnutrition by 2030. Given the numbers of food insecure and malnourished people on the rise, the heterogeneity of nutritional statuses and needs, and the even worse context of COVID-19 pandemic, this has become an urgent challenge for food-related policies. This paper provides a comprehensive microsimulation approach to evaluate economic policies on food access, sufficiency (energy) and adequacy (protein, fat, carbohydrate) at household level. The improvement in market access conditions in Kenya is simulated as an application case of this method, using original insights from households’ surveys and biochemical and nutritional information by food item. Simulation’s results suggest that improving market access increases food purchasing power overall the country, with a pro-poor impact in rural areas. The daily energy consumption per capita and macronutrients intakes per capita increase at the national level, being the households with at least one stunted child under 5 years old, and poor households living areas outside Mombasa and Nairobi, those which benefit the most. The developed method and its Kenya's application contribute to the discussion on how to evaluate nutrition-sensitive policies, and how to cover most households suffering food insecurity and nutrition deficiencies in any given country.
STANISŁAW KUCZERA (5 MAY 1928–28 JULY 2020)
Authors: Dmitriev Sergey 
Published: September 2021

AbstractStanisław Kuczera (May 5, 1928–July 28, 2020) was an eminent figure in Polish, Soviet, and Russian Chinese Studies, holding the position of one of leading experts in a vast number of fields (most prominently, archeology, epigraphy, and the translation of classics) over a period decades, until his last days. His life, filled with a thirst for knowledge and harsh vicissitudes, is a story that is worthy of being told and remembered.
Chaotic behavior of the p-adic Potts–Bethe mapping II
Authors: KHAKIMOV OTABEK , MUKHAMEDOV FARRUKH 
Published: September 2021

AbstractThe renormalization group method has been developed to investigate p-adic q-state Potts models on the Cayley tree of order k. This method is closely related to the examination of dynamical behavior of the p-adic Potts–Bethe mapping which depends on the parameters q, k. In Mukhamedov and Khakimov [Chaotic behavior of the p-adic Potts–Behte mapping. Discrete Contin. Dyn. Syst.38 (2018), 231–245], we have considered the case when q is not divisible by p and, under some conditions, it was established that the mapping is conjugate to the full shift on
$\kappa _p$
symbols (here
$\kappa _p$
is the greatest common factor of k and
$p-1$
). The present paper is a continuation of the forementioned paper, but here we investigate the case when q is divisible by p and k is arbitrary. We are able to fully describe the dynamical behavior of the p-adic Potts–Bethe mapping by means of a Markov partition. Moreover, the existence of a Julia set is established, over which the mapping exhibits a chaotic behavior. We point out that a similar result is not known in the case of real numbers (with rigorous proofs).
Massey products in the homology of the loop space of a p-completed classifying space: finite groups with cyclic Sylow p-subgroups
Authors: Benson Dave , Greenlees John 
Published: September 2021

AbstractLet $G$ be a finite group with cyclic Sylow $p$-subgroups, and let $k$ be a field of characteristic $p$. Then $H^{*}(BG;k)$ and $H_*(\Omega BG{{}^{{}^{\wedge }}_p};k)$ are $A_\infty$ algebras whose structure we determine up to quasi-isomorphism.
Music as a social bond in patients with amnesia
Authors: Del Mastro Maria Chiara , Strollo Maria Rosaria , El Haj Mohamad 
Published: September 2021

Abstract
The music and social bonding (MSB) hypothesis proposes that human musicality has evolved as mechanisms supporting social bonding. We consider the MSB hypothesis under the lens of amnesia by arguing how patients with amnesia, especially those with Alzheimer's disease, can benefit from music, not only to retrieve personal memories, but also to use them for social bonding.
If it quacks like a duck: The by-product account of music still stands
Authors: Lieberman Debra , Billingsley Joseph 
Published: September 2021

Abstract
Discerning adaptations from by-products is a defining feature of evolutionary science. Mehr, Krasnow, Bryant, and Hagen posit that music is an adaptation that evolved to function as a credible signal. We counter this claim, as we are not convinced they have dispelled the possibility that music is an elaboration of extant features of language.
Signaling games and music as a credible signal
Authors: Lumaca Massimo , Brattico Elvira , Baggio Giosuè 
Published: September 2021

Abstract
The argument by Mehr et al. that music emerged and evolved culturally as a credible signal is convincing, but it lacks one essential ingredient: a model of signaling behavior that supports the main hypothesis theoretically and empirically. We argue that signaling games can help us explain how musical structures emerge as population-level phenomena, through sender–receiver signaling interactions.
Social bonding and music: Evidence from lesions to the ventromedial prefrontal cortex
Authors: Belfi Amy M. 
Published: September 2021

AbstractThe music and social bonding (MSB) hypothesis suggests that damage to brain regions in the proposed neurobiological model, including the ventromedial prefrontal cortex (vmPFC), would disrupt the social and emotional effects of music. This commentary evaluates prior research in persons with vmPFC damage in light of the predictions put forth by the MSB hypothesis.
Making music: Let's not be too quick to abandon the byproduct hypothesis
Authors: Stewart-Williams Steve 
Published: September 2021

Abstract
It is premature to conclude that music is an adaptation. Given the danger of overextending the adaptationist mode of explanation, the default position should be the byproduct hypothesis, and it should take very strong evidence to drag us into the adaptationist camp. As yet, the evidence isn't strong enough – and the proposed adaptationist explanations have a number of unresolved difficulties.
Ecological and psychological factors in the cultural evolution of music
Authors: Scott-Phillips Thom , Tominaga Atsuko , Miton Helena 
Published: September 2021

Abstract
The two target articles agree that processes of cultural evolution generate richness and diversity in music, but neither address this question in a focused way. We sketch one way to proceed – and hence suggest how the target articles differ not only in empirical claims, but also in their tacit, prior assumptions about the relationship between cognition and culture.
Music as a trait in evolutionary theory: A musicological perspective
Authors: Wald-Fuhrmann Melanie , Pearson Lara , Roeske Tina , Grüny Christian , Polak Rainer 
Published: September 2021

AbstractAlthough it can be straightforward to define the features of physical traits, complex cultural categories tend to elude widely accepted definitions that transcend cultural and historical context. Addressing papers by Mehr et al. and Savage et al., which both aim to explain music as an evolved trait, we discuss fundamental problems that arise from their conceptualizations of music.
Is neural entrainment to rhythms the basis of social bonding through music?
Authors: Grahn Jessica A. , Bauer Anna-Katharina R. , Zamm Anna 
Published: September 2021

Abstract
Music uses the evolutionarily unique temporal sensitivity of the auditory system and its tight coupling to the motor system to create a common neurophysiological clock between individuals that facilitates action coordination. We propose that this shared common clock arises from entrainment to musical rhythms, the process by which partners' brains and bodies become temporally aligned to the same rhythmic pulse.
A neurodevelopmental disorders perspective into music, social attention, and social bonding
Authors: Kasdan Anna , Gordon Reyna L. , Lense Miriam D. 
Published: September 2021

Abstract
Our commentary addresses how two neurodevelopmental disorders, Williams syndrome and autism spectrum disorder, provide novel insights into the credible signaling and music and social bonding hypotheses presented in the two target articles. We suggest that these neurodevelopmental disorders, characterized by atypical social communication, allow us to test hypotheses about music, social bonding, and their underlying neurobiology.
Music as social bonding: A cross-cultural perspective
Authors: Zou Ivan Yifan , Wang William S.-Y. 
Published: September 2021

AbstractWe extend Savage et al.'s music and social bonding hypothesis by examining it in the context of Chinese music. First, top-down functions such as music as political instrument should receive more attention. Second, solo performance can serve as important cues for social identity. Third, a right match between the tones in lyrics and music contributes also to social bonding.
Musicality was not selected for, rather humans have a good reason to learn music
Authors: Atzil Shir , Abramson Lior 
Published: September 2021

AbstractWe propose that not social bonding, but rather a different mechanism underlies the development of musicality: being unable to survive alone. The evolutionary constraint of being dependent on other humans for survival provides the ultimate driving force for acquiring human faculties such as sociality and musicality, through mechanisms of learning and neural plasticity. This evolutionary mechanism maximizes adaptation to a dynamic environment.
Music, bonding, and human evolution: A critique
Authors: Merker Bjorn 
Published: September 2021

AbstractSavage et al. propose that music filled a hypothetical “bonding gap” in human sociality by Baldwinian gene-culture coevolution (or protracted cognitive niche construction). Both these stepping stones to an evolutionary account of the function and origin of music are problematic. They are scrutinized in this commentary, and an alternative is proposed.
Credible signalling and social bonds: Ultimately drawing on the same idea
Authors: Kennedy Patrick , Radford Andrew N. 
Published: September 2021

Abstract
The hypotheses in both target articles rely implicitly on much the same logic. For a “social-bonding” device to make sense, there must be an underlying reason why an otherwise-arbitrary behaviour sustains alliances – namely, credible signals of one's value to partners. To illustrate our points, we draw on the parallels with supposed bonding behaviours in nonhuman animals.
Functional and evolutionary parallels between birdsong and human musicality
Authors: Snyder Kate T. , Creanza Nicole 
Published: September 2021

Abstract
Here, we compare birdsong and human musicality using insights from songbird neuroethology and evolution. For example, neural recordings during songbird duetting and other coordinated vocal behaviors could inform mechanistic hypotheses regarding human brain function during music-making. Furthermore, considering songbird evolution as a model system suggests that selection favoring certain culturally transmitted behaviors can indirectly select for associated underlying neural functions.
Is the MSB hypothesis (music as a coevolved system for social bonding) testable in the Popperian sense?
Authors: Fritz Jonathan B. 
Published: September 2021

Abstract
“Music As a Coevolved System for Social Bonding” (MSB) is a brilliant synthesis and appealing hypothesis offering insights into the evolution and social bonding of musicality, but is so broad and sweeping it will be challenging to test, prove or falsify in the Popperian sense (Popper, 1959). After general comments, I focus my critique on underlying neurobiological mechanisms, and offer some suggestions for experimental tests of MSB.
Reducing behavioral dimensions to study brain–environment interactions
Authors: Thura David 
Published: September 2021

Abstract
Movement vigor provides a window on action valuation. But what is vigor, and how to measure it in the first place? Strikingly, many different co-varying vigor-related metrics can be found in the literature. I believe this is because vigor, just like the neural circuits that determine it, is an integrated, low-dimensional parameter. As such, it can only be roughly estimated.
Time and the decider
Authors: Spurrett David 
Published: September 2021

Abstract
Shadmehr and Ahmed's book is a welcome extension of optimal foraging theory and neuroeconomics, achieved by integrating both with parameters relating to effort and rate of movement. Their most persuasive and prolific data come from saccades, where times before and after decision are reasonably determinate. Skeletal movements are less likely to exhibit such tidy temporal organization.
A role of serotonin and the insula in vigor: Tracking environmental and physiological resources
Authors: Tops Mattie , Boksem Maarten A. S. , Montero-Marin Jesus , van der Linden Dimitri 
Published: September 2021

AbstractWe describe a neural monitor of environmental and physiological resources that informs effort expenditure. Depending on resources and environmental stability, serotonergic and dopaminergic neuromodulations favor different behavioral controls that are organized in corticostriatal loops. This broader perspective produces some suggestions and questions that may not be covered by the foraging approach to vigor of Shadmehr and Ahmed (2020).