bluuebunny/crossref_metadata_2025_split huggingface dataset:
Time Management to Reduce Delays in Middle School Students
Authors: Purnamasari Aini Nadhifah , Suroso Suroso 
Published: August 2021

This study aimed to determine the effectiveness of providing time management assistance. to reduce the intensity of tardiness in 7th grade female students. This research is an experimental study with a single subject research. Interventions were carried out on research subjects and parents. Intervention by accompanying the subject in managing the time of daily activities clearly and in writing, while the subject of intervention in parents is psychoeducation. Interventions conducted on the subject were done in 4 sessions with each session carried out for 60 minutes where in the first session the subject was given an explanation of the importance of time management, in the second session the subject was asked to detail the important daily activities and must be carried out and determine the time at each activity, in the third session the subjects were asked to evaluate related matters that did not support the fulfillment of the specified time management and the things that might be done to keep doing activities in accordance with the time specified and for the fourth session the subjects were asked to evaluate the entire intervention process and conclude with regard to its effects. The intervention that was carried out to parents was carried out 1 time with a duration of 30 minutes. The result of the intervention is that the research subject can manage the time of daily activities more clearly and in writing so that he can follow the set time. In the subject's parents, the subject's mother understood more about the subject's problems and needs so that the parents paid more attention to the subject and determined someone to bring the subject to school at the designated time. From the interventions carried out, there are changes in the way of thinking and attitudes towards the subject and parents of the subject which are expected to reduce the intensity of the subject's lateness to school.
Factors Subjective Well-Being Santri are Practicing Fasting Ngrowot
Authors: Alfadla Maya Tsuroya , Trisnawati Putri Laras 
Published: August 2021

Kesejahteraan subjektif adalah persepsi dan pengalaman pribadi dari respon emosional positif dan negatif yang mengarah kepada kepuasan hidup seseorang. Seyogjanya seorang santri yang mengamalkan puasa ngrowot memiliki kesejahteraan subjektif pula meskipun harus menahan diri untuk memakan nasi sebagai upaya mendekatkan diri kepada Tuhan. Tujuan penelitian ini untuk mengkaji faktor-faktor kesejahteraan subjektif santri yang mengamalkan puasa ngrowot. Metode penelitian yang digunakan adalah penelitian kualitiatif dengan pendekatan fenomenologi yang diartikan sebagai pandangan berfikir yang menekankan pada fokus pengalaman-pengalaman subjektif manusia dan interpretasi-interpretasi dunia. Terdapat empat faktor yang memengaruhi kesejahteraan subjektif santri yang mengamalkan puasa ngrowot antara lain; spiritualitas berupa keyakinan maupun ritual, kepasrahan, dukungan sosial, dan tujuan hidup.
Real meaning of Togay Murad's novel "Fields left by my father"
Authors: Kenjayeva Munira  
Published: August 2021

Togay Murad's heroes fit the spirit of the time, especially the worldview of independent youth. Our national traditions and nationality are very bright in it. It is for this reason that the writer realizes the problem before his contemporaries. Togay Murad encourages them to do the same. In his novel “The Fields Left by My Father”, three members of an Uzbek peasant dynasty - grandfather, father and son - represent the fate of the Uzbek people's 130 years of oppression. His life is revealed with artistic skill. In this article I am on the verse to describe this historical period in details.
Optimization of Employee Workload to Achieve Effectiveness of Man Power Planning at PT. SPINDO Depo Samarinda
Authors: Budi Setya , Putra Boy Isma , Cahyana Athika Sidhi , Sari W Indah Apriliana 
Published: August 2021

Intense competition in today's industrial world requires companies to keep abreast of developments. The more years, higher the need for labor costs. To reduce high production costs, one step is to cut existing labor. By cutting the number of workers, the workload that will be borne by workers will also increase. PT. SPINDO, is a manufacturing company engaged in the production of the steel pipe industry. To expand market reach, a breakthrough was made to open a new depot located in the city of Samarinda. At the beginning of the opening along with the Covid-19 outbreak, market demand was minimal. The impact on the work load in the depot is also low. The Full Time Equivalent method is a calculation process that uses working time as a reference in determining workload. In this research, the workload value most of the employees at PT. SPINDO Depo Samarinda is included in the underload category. So that man power planning is needed by cutting the number of existing employees to balance work load and the number of manpower. After the manpower planning was carried out, the work load that was previously unbalanced was balanced because the workload had been distributed to the employees.
Selection of Fish Raw Material Suppliers by Integrating ANP and Topsis Methods in CV. Riki Utama Mandiri
Authors: Fajar Iman Sakti Aula , Sulistiyowati Wiwik 
Published: August 2021

CV. Riki Utama Mandiri is a company in distributing an economic fish frozen product. This company distributed any kind of retail and wholesaler, both domestic and export. They distributing many frozen fish products variant such as Patin Fillet and Shark Fin. The all raw materials of those frozen seafood was obtained by three different suppliers. The common problems found in CV. Riki Utama Mandiri mostly about raw patin fish supplier which often committed delivery delays. The purpose of this research is to fixing the supply chain management in deciding the more accurate selections of raw materials supplier. To overcome the common problems that happen. Analytical network process (ANP) will simplify the criteria weight values and sub criteria of each supplier. Meanwhile, technique for others reference by similarity to ideal solution (TOPSIS) method is used for giving a rank order of the alternative supplier. This research is expected for being a consideration for the company in obtaining a good and more effective kind of raw supplier. We also expecting the company for tighten supplier selection more effective way so that it can fullfilled the existing standard. Also to overcome the common problems such as delivery delays, competing raw materials with uncertain quality, and difficulty in sort out the raw materials due to size issues.
Optimization Of Cutting Chicken Routes
Authors: Sunandi Ovi Miru , Sulistiyowati Wiwik 
Published: August 2021

This study has the title Optimization of Chicken Cut Retrieval Route. The existence of this study aims to reduce the distance of chicken retrieval routes from cages to slaughter mills, as well as reduce the number of deaths and chicken kesetresan when descending from the chicken carrier fleet. The method in the study used saving matrix method and vehicle routing problem. The method of data collection used is to take primary data that is taken data from the location of cut parik and chicken coop taken by the fleet so far and secondary data taken dati preentase route from the slaughter plant to the chicken coop. And obtained the maximum chicken cut and decreased the death rate and chicken kesetresan with the length of saving matrix route 219.58 Km, using 5 trucks, spent fuel Rp. 141.263, and driver's salary of Rp. 26.250.000. While using vehicle routing problem route length 209.38 Km, using 5 trucks, spent fuel Rp. 134.775, and driver's salary of Rp. 26.250.000.
Deletion of Dnm1 Gene In Mitochondria Lead To The Changes of Cell Dynamics and Energy Metabolism In Fission Yeast
Authors: Tan Xiumei , Ding Xiang , Yuan Rongmei , Hou Yiling 
Published: August 2021

Abstract
Mitochondria are dynamic organelles that undergo cycles of fission and fusion. The major mitochondrial fission protein is dynamin-related Drp1 GTPase (Dnm1 in yeast). The effects of Dnm1 gene deletion on cell dynamics and energy metabolism during mitosis were studied in Schizosaccharomyces pombe. Dnm1 gene deletion can lead to slow growth, abnormal sporulation, abnormal number and length of interphase microtubules of Schizosaccharomyces pombe. The deletion of Dnm1 gene can also affect the spindle growth speed and growth time of metaphase and anaphase, and affect the spindle fluorescence intensity of prophase and metaphase. At the same time, the structure and dynamics of the spindle microtubules of Dnm1Δ are also different. The statistics of spindle length showed that there was delayed spindle fracture in Dnm1Δ Cells. Two different chromosome behaviors, normal and lagged, were observed by living cell imaging. The analysis of coenzymes, intermediates and energy in energy metabolism showed that there were some abnormalities after Dnm1 gene deletion, including coenzyme defects, intermediate metabolite defects and ATP production defects.
Phyto Mediated Silver Nanoparticle Synthesis Coated Fabrics Towards Antibacterial Potential
Authors: Kabeerdass Nivedhitha , Murugesan Karthikeyan , Ramasamy Srinivasan , Mathanmohun Maghimaa 
Published: August 2021

Abstract
Sore repairing since occurrence up to dry skin formation (scar) is a precious process gifted by nature. Immunology takes a predominant part in healing. A sore which is sustained just now, within minutes/hours is usually ignored till its uninterrupted scar formation. When is delayed that persists for many days, many weeks, more months, even for years is keenly noticed and is seeking secondary healing which is donated by medical men. Uninterrupted natural healing is usually processed by the immune system of the host when healing is delayed then comes interruption of the medical experts with the inclusive of medicines such as synthetic chemicals, phytotherapy, micro nano particles mingled medicines, botanical flora yield Phyto metal micro therapies which going for updated management like 3D bioprinting is in practice. An array of twenty exudates of nasal, pus, urine, stool, and blood are collected from the diverse age group of sex in various wards of SOTS (such as ICU, CCU, maternity, and casualty) from the Hospitals of Madurai. After isolating from other commensals its phenotypic character is studied through gram staining and biochemical tests. To get rid of their pathogenicity a cheap, cost-effective, eco-friendly potential medicinal ingredients possessed Amaranthaceae family yielded Alternanthera sessilis mediated fabrics coated silver nanoparticles were synthesized. In the case of MIC of AS-AgNPs against isolates zone of inhibition of the E. coli is 16mm > S. aureus is 15mm at 60µg. But in the case of MIC of fabrics against isolates the E. coli and K. oxytoca show susceptibility of 19 mm in mixed cotton. In a confirmation study of AS-AgNPs in FTIR, a sharp band is observed between 1500-500cm-1, in SEM with EDAX a graph was observed between 2.6–3.9 and black white crystals measured at 200nm in HR-TEM. Nanotechnology conjoined with herbal therapeutics provides a promising solution for wound management strategies.
Application Research on End-To-End Deep Person Re-Identification
Authors: Xu Qingzhen , Qiao Han , Liu Shuang , Liu Shouqiang 
Published: August 2021

Abstract
Pedestrian detection refers to the technology of predicting and locating the location of pedestrians in video or image. However, the recognition accuracy of existing re-identification methods needs to be improved. In this paper, the deep learning method is adopted, and the pedestrian detection based on YOLOV3-spp is combined with the pedestrian re-identification based on Resnet50, to construct the deep pedestrian re-identification system. In the training part, the COCO training set containing only pedestrian images is used to train pedestrian detection. WGAN-GP was used to expand the pedestrian re-identification training set of Market1501, and pedestrian re-recognition training was carried out on the expanded dataset to reduce the interference of pose diversity in the learning process. In the detection part, the system first uses the pedestrian detection to locate the original image and cut out the corresponding image, then input the cut image and the target image into the person re-identification network to learn the image features, and finally the classifier judges the image containing the target. In the experiment, the identification accuracy of the system is 87.5% on the Market-1501 test set, and the identification speed of each picture is 0.12s.
Stemness and NK-like signatures define a subtype of esophageal squamous cell carcinoma with poor prognosis
Authors: Jiang Guozhong , Wang Zhizhong , Cheng Zhenguo , Wang WeiWei , Zhang Zifang , Lu Shuangshuang , Xu Huisha , Dong Yunshu , Chen Peinan , Zhang Zhongxian , Gao Dongling , Wang Zhimin , Miao Jinxin , Xue Xia , Wang Pengju , Zhang Lirong , Gangeswaran Rathi , Liu Peng , Dunmal Louisa Chard , Li Junkuo , Guo Yongjun , Dong Jianzeng , Lemoine Nicholas , Li Wencai , Wang Jun , Wang Yaohe 
Published: August 2021

Abstract

To explore the biology of esophageal squamous cell carcinoma (ESCC) and identify new therapeutic opportunities, comprehensive genomic-transcriptomic characterizations of 120 Chinese ESCC patients were performed. Here we show that ESCC can be categorized into differentiated, metabolic, immunogenic and stemness subtypes based on transcriptomics, with each subtype exhibiting unique molecular and histopathological features. The stemness subgroup, with four key signature genes (WFDC2, SFRP1, LGR6 and VWA2), has the poorest prognosis and was associated with downregulated immune activities, a high frequency of EP300 mutation/activation, functional mutation enrichment in Wnt signalling and the highest level of intratumoural heterogeneity. The immune profiling further revealed ESCC tumour cells overexpress NK cell markers XCL1/2 and CD160 as a new immune evasion strategy. Strikingly, XCL1 expression also affects the sensitivity of ESCC cells to common chemotherapy drugs. This study opens up new avenues for ESCC treatment and provides a unique public resource to better understand and treat ESCC.
­Actual Evapotranspiration for Sugarcane Based on Bowen Ratio-Energy Balance and Soil Water Balance Models with Optimized Crop Coefficients.
Authors: Martins Suelen da Costa Faria , Santos Marcos Alex dos , Lyra Gustavo Bastos , Souza José Leonaldo , Lyra Guilherme Bastos , Teodoro Iêdo , Ferreira Fábio Freitas , Júnior Ricardo Araújo Ferreira , Almeida Alexsandro Claudio dos Santos , de Souza Renan Cantalice 
Published: August 2021

Abstract
Evapotranspiration is an important parameter to evaluate soil water deficit and water use efficiency, especially at places with irregularly distributed precipitation.The aim of this study was to assess the daily actual evapotranspiration (ETa) estimated by the Thornthwaite and Mather soil water balance method adapted for crops (ThM) and by the dual Kc approach with the crop coefficients optimized from inversing modeling and by the adjustment procedure suggested in FAO-56. The models comparison and optimization were performed with actual evapotranspiration determined by the Bowen ratio – energy balance method (ETβ) for sugarcane at full canopy closure grown in Alagoas State, Northeastern Brazil. The objective function of the inverse problem was defined in terms of ETβ and ETa estimated by the ThM and dual Kc method by optimizing single crop coefficient (Kc) and the basal coefficient Kcb, respectively. Both optimized Kcand Kcbwere lower than the adjusted KcFAO56, with optimized Kconly 3% less than the Kc obtained experimentally. ETa estimated by ThM and dual Kc models with optimized crop coefficients (Kc = 1.05 or Kcb = 1.00) had similar high precision (r² >0.79) and accuracy (dm>0.93 and RMSE < 0.30 mm d-1), whereas using the coefficients derived from FAO 56 overestimated ETa in both models.
A Comparison of Symptoms and Signs in Patients with Inflammatory Dry Eye Disease using two Commercially Available Treatment Formulations of Cyclosporine A
Authors: Olafsson Jonatan , Olafsson Snorri , Hammer Hugo Lewi , Tashbayev Behzod , Utheim Øygunn A. , Chen Xiangjun , Raeder Sten , Lagali Neil , Dartt Darlene A. , Utheim Tor P. 
Published: August 2021

Abstract
Purpose: Dry eye (DED) is a multifactorial disease of the ocular surface in which ocular surface inflammation and damage play etiological roles. In the present study, we compared symptoms and signs in patients with DED treated with 0.1% Cyclosporine A (CsA) cationic emulsion (Ikervis, Santen) and 0.05% CsA anionic emulsion (Restasis, Allergan).Methods: Single-center, retrospective, 202 consecutive DED patients were treated with 0.1% CsA cationic emulsion (Ikervis, n=101) or 0.05% CsA anionic emulsion (Restasis, n=101) over six months. Ophthalmological work-up included Ocular Surface Disease Index (OSDI) questionnaire, fluorescein break-up time (FBUT), fluorescein ocular surface staining (OSS), Schirmer’s test, meibum expressibility (ME), and meibum quality (MQ). Results: In both treatment groups, subgroup analysis revealed a significant improvement of OSDI only in patients with severe symptoms at baseline (OSDI 33-100). Ikervis-treated patients with OSDI <23 at baseline had a significant increase in symptoms. OSS and FBUT improved significantly in most subgroups irrespective of Ikervis or Restasis being used. Regression analysis revealed a significant superiority to Restasis with regard to FBUT improvement and superiority to Ikervis in regards ME improvement. Conclusions: We conclude that there is seemingly no substantial difference in efficacy between the two drugs. The strength of Restasis is increased efficacy at improving FBUT and of Ikervis improving ME.
Venetoclax and Azacitidine Therapy in Elder Acute Myeloid Leukemia: A Retrospective Evaluation of Real-World Experience
Authors: Hu Rong-Hua , Su Li , Lan Xiao-Xi , Chang Xiao-Li , Hui Wu-Han , Zhao Hong , Guo Yi-Xian , Wang Guo-Xiang , Sun Wan-Ling 
Published: August 2021

Abstract
Background：To investigate the efficacy of venetoclax combined with azacytidine in the treatment of elderly patients with relapsed and refractory (R/R) acute myeloid leukemia（AML). Methods： The clinical data of 9 elderly AML patients over 65 years old, including 5 with R/R AML, using venetoclax and azacytidine were retrospectively analyzed. Results： Six males and 3 females with a median age of 71 years were included in this study, of which four patients had at least one relapse, and one patient did not get go into remission after 4 cycles of azacytidine monotherapy, deeming it refractory. Four patients had AML with myelodysplasia-related changes (AML-MRC). After 1 to 13 cycles of treatment using venetoclax and azacytidine, one of the 9 patients died early due to long duration of neutropenia and severe pulmonary infection caused by drugs. and six of the remaining 8 patients obtained complete response or complete response with incomplete hematologic recovery (CR/ CRi) , including five R/R patients. One patient did not respond to treatment after two cycles. For the side effects of the treatment, granulocytopenia occurred in all patients, and neutropenia occurred in 8 patients, lasting for an average of 10.5 (6-15) days and was most obvious in the second to third week of treatment. Three patients with TP53 gene mutation positive had following different outcomes. One relapsed patient achieved progression free remission (PFS) for 16 months up to date, and a second patient achieved complete remission but relapsed two months thereafter. Another patient had complete remission in myelology for 4months, but the variant allele fraction value (VAF) gradually increased, indicative that the disease was about to progress. Conclusion：Venetoclax combined with azacytidine regimen in elderly patients is an effective and well tolerated rescue scheme for R/R AML.The patients with TP53 mutation with lower VAF may be benifit from Venetoclax and azacytidine. Severe infection caused by neutropenia is an adverse reaction worthy of attention in the treatment process of the regimen.
Impacts of structural change in global trade on sustainable development
Authors: Wang Jiayu , Wang Ke , Hubacek Klaus , Feng Kuishuang , Shan Yuli , Wei Yi-Ming 
Published: August 2021

Abstract
The 2030 Agenda for Sustainable Development pursues 17 sustainable development goals (SDGs), the achievement of which may be influenced by a country’s role in global supply chains and position in international trade patterns. Global trade changes constantly with an increasing share of flows between developing countries. However, little is known about the impacts of change in trade on multi-dimensions of sustainable development at both global and country levels. Here we assess how structural change in trade during three time periods, between 2004 and 2014, impact 13 SDG indicators in 141 countries or regions. We find that socio-economic indicators (e.g., high- and medium-skilled labor, GDP) are less sensitive to change in trade, compared with resource and environmental indicators (e.g., water consumption, GHG emissions). Moreover, change in trade aggravated inequality among countries. The number of indicators that significantly worsened by change in trade decreased from eight indicators (2004–2007) to one (2011–2014) for high-income and upper-middle-income countries, but increased from five to fourteen for lower-middle-income and low-income countries. Furthermore, change in trade led to a coupling of value added with most resource and environmental indicators for low-income countries, while strengthening decoupling or reducing coupling for other countries.