bluuebunny/crossref_metadata_2025_split huggingface dataset:
Egyptian practical guidance in lipid management 2020
Authors: Taha Hesham Salah El Din , Badran Hala Mahfouz , Kandil Hossam , Farag Nabil , Oraby Abbas , El Sharkawy Magdy , Shokry Khaled , Fawzy Fouad , Mahrous Hossam , Bahgat Juliette , Samy Mina , Shaker Mirna Mamdouh 
Published: February 2021

Abstract
Background
Numerous epidemiological investigations and randomized clinical studies have determined that dyslipidemia is a major contributor to atherosclerotic cardiovascular disease (ASCVD). Consequently, the management of serum cholesterol and low-density lipoprotein levels has become a central objective in the effort to prevent cardiovascular events.

Main body
Many guidelines were issued by different organizations and societies to define patient risk and establish important recommendations for management strategies. Newer cholesterol-lowering agents (non-statin drugs) are described, and their use is directed primarily to secondary prevention in patients at very high risk of new ASCVD.

Conclusion
The present guidance summarizes the current methods for risk estimation and outlines the most recent data on lipid management in a simple user-friendly format, to improve physician awareness and help implement guidelines in the daily practice.
Research priorities in maternal and neonatal health in Africa: results using the Child Health and Nutrition Research Initiative method involving over 900 experts across the continent
Authors: Alobo Moses , Mgone Charles , Lawn Joy , Adhiambo Colette , Wazny Kerri , Ezeaka Chinyere , Molyneux Elizabeth , Temmerman Marleen , Okong Pius , Malata Address , Kariuki Thomas ,   African Academy of Sciences Maternal and Neonatal Health Working Group for Africa
Published: February 2021

Background:Africa will miss the maternal and neonatal health (MNH) Sustainable Development Goals (SDGs) targets if the current trajectory is followed. The African Academy of Sciences has formed an expert maternal and newborn health group to discuss actions to improve MNH SDG targets. The team, among other recommendations, chose to implement an MNH research prioritization exercise for Africa covering four grand challenge areas.Methods: The team used the Child Health and Nutrition Research Initiative (CHNRI) research prioritization method to identify research priorities in maternal and newborn health in Africa. From 609 research options, a ranking of the top 46 research questions was achieved. Research priority scores and agreement statistics were calculated, with sub-analysis possible for the regions of East Africa, West Africa and those living out of the continent. Results:The top research priorities generally fell into (i) improving identification of high-risk mothers and newborns, or diagnosis of high-risk conditions in mothers and newborns to improve health outcomes; (ii) improving access to treatment through improving incentives to attract and retain skilled health workers in remote, rural areas, improving emergency transport, and assessing health systems' readiness; and (iii) improving uptake of proven existing interventions such as Kangaroo Mother Care.Conclusions:The research priorities emphasized building interventions that improved access to quality healthcare in the lowest possible units of the provision of MNH interventions. The lists prioritized participation of communities in delivering MNH interventions. The current burden of disease from MNCH in Africa aligns well with the list of priorities listed from this exercise but provides extra insights into current needs by African practitioners.The MNCH Africa expert group believes that the recommendations from this work should be implemented by multisectoral teams as soon as possible to provide adequate lead time for results of the succeeding programmes to be seen before 2030.
The mother during pregnancy and the puerperium: Detailed data abstracted from the clinical obstetric records of ALSPAC pregnancies
Authors: Birmingham Karen , Gregory Steven , Iles-Caven Yasmin , Fraser Abigail , Lawlor Deborah A. , Boyd Andrew , Northstone Kate , Golding Jean 
Published: February 2021

Background: When the Avon Longitudinal Study of Parents and Children (ALSPAC) was planned, it was assumed that the clinical obstetric data would be easily accessible from the newly developed National Health Service computerised ‘STORK’ system. Pilot studies, however, showed that, although fairly accurate in regard to aspects of labour and delivery, it was, at the time (1990-2), inadequate for identifying the full antenatal and postnatal details of clinical complications and treatments of the women in the Study. Methods: A scheme was therefore developed to train research staff to find and abstract relevant details from clinical records onto proformas designed for the purpose. Extracting such data proved very time consuming (up to six hours for complicated pregnancies) and consequently expensive. Funding for the enterprise was obtained piecemeal using specific focussed grants to extract data for subsamples of the Study, including a random sample to serve as controls. Results: To date, detailed records have been completed for 8369 pregnancies, and a further 5336 (13,705 in total) have complete details on specific prenatal areas, including serial measures of maternal blood pressure, proteinuria and weight. In this Data Note we describe the information abstracted from the obstetric medical records concerning the mother during pregnancy, labour, delivery and the first two weeks of the puerperium. Information abstracted relating to the fetus (including fetal monitoring, presentation, method of delivery) and neonate (signs of asphyxia, resuscitation, treatment and well-being) will be described in a further Data Note. Conclusions: These data add depth to ALSPAC concerning ways in which the signs and symptoms, procedures and treatments of the mother prenatally, intrapartum and postnatally, may impact on the long-term health and development of both mother and child. They augment the data collected from the mothers’ questionnaires and the ‘STORK’ digital hospital data.
Policy Uncertainty and Innovation: Evidence from Initial Public Offering Interventions in China
Authors: Cong Lin William , Howell Sabrina T. 
Published: February 2021

Public equity is an important source of risk capital, especially in China. The Chinese government has occasionally suspended IPOs, exposing firms already approved to IPO to indeterminate listing delays. The temporary bar on going public increases uncertainty about access to public markets for affected firms. We show that suspension-induced delay reduces corporate innovation activity both during the delay and for years after listing. Negative effects on tangible investment and positive effects on leverage are temporary, consistent with financial constraints during the suspensions being resolved after listing. Our results suggest that predictable, well-functioning IPO markets are important for firm value creation. They demonstrate that corporate innovation is cumulative and is negatively affected by policy uncertainty. This paper was accepted by Gustavo Manso, finance.
Alzheimer's disease research: past approaches and future directions
Authors: Yehuda Michael Ben , Lawson Jennifer , Raymont Vanessa 
Published: February 2021

Background: Three decades after the amyloid cascade hypothesis was first proposed, research into discovery of effective treatments for Alzheimer's disease has not yet produced any disease-modifying treatments. Aims: This review outlines the progress made by dementia research thus far, and provides a brief overview of the therapeutic approaches resulting from the amyloid cascade hypothesis. It then describes the shift in research focus to the early stages of the condition, the challenges it presents and potential consequences for care. Methods: A literature overview was undertaken by reviewing research papers, published protocols and policy guidelines. Findings: Past research has failed to produce effective treatments for dementia, yet the causes of this failure remain debated. Discovery of affordable, early biomarkers has emerged as a key target of investigation as the focus has shifted from treatment to prevention of the condition. Conclusions: Failures in identifying effective treatments for dementia have highlighted the importance of earlyidentification and intervention in patients as a way to prevent neurodegeneration and progression to dementia. Discovery of biomarkers is a key focus of current research. In the future, regular screening for dementia may be recommended for all older people in an effort to assess individual risk. Care may reflect a combination of early pharmacological interventions and lifestyle modification programmesbased on risk.
Ultrahigh sensitive surface plasmon sensor using a nanofilm coated D-type
photonic crystal fiber
Authors: Liu Xuanyi , Melwin G. , Gandhi M. S. Aruna , Fu H. Y. , Babu P. Ramesh , Senthilnathan K. , Li Qian 
Published: February 2021

We investigate a novel, to the best of our knowledge, D-type photonic crystal fiber-based refractive
index microbiosensor that works on surface plasmon resonance. We study
the performance of the proposed sensor using the finite element
method. Further, we analyze the influence of various materials,
namely, gold, silver, and indium tin oxide that are deposited on the
D-type fiber surface. Of these metals, gold has been examined to be
advantageous owing to its enhanced sensitivity and greater chemical
stability. The proposed microbiosensor exhibits a high wavelength
sensitivity of 19,000 nm/RIU in the sensing range of 1.40–1.41, and
its wavelength interrogation resolution is

5.26
×

10

−
6

RIU. Besides, this novel scheme
provides a high amplitude sensitivity of

569

R
I
U

−
1

with the corresponding resolution of

2.63
×

10

−
6

RIU. Further, the linearity of the
proposed microbiosensor,

R

2

, is 0.9745 in the sensing environment
of the refractive index ranging between 1.31 and 1.40. Finally,
optimizing the metal coating thickness, diameter of the air-hole, and
the lattice pitch of the proposed sensor have been conducted
systematically, in order to augment the sensing performance of the
proposed sensor. We foresee that the proposed microbiosensor would
turn out to be an appropriate candidate in sensing the analytes of
high refractive index.
Compact silicon-based TE-pass polarizer using a symmetrical triple-guide directional coupler including SWG structures and hybrid plasmonic waveguides
Authors: Yang Nan , Xiao Jinbiao 
Published: February 2021

A compact and broadband silicon-based transverse-electric (TE)-pass polarizer based on a symmetrical triple-guide directional coupler (TW-DC) is presented and analyzed in detail, assisted with subwavelength gratings (SWGs) and hybrid plasmonic waveguides (HPWs), where the SWGs are involved at the inner part of its central waveguide and two HPWs are introduced and symmetrically located at its outer sides. By carefully improving the structural parameters, only the injected TE mode can be supported by SWGs, and it passes through the device directly due to phase mismatching, while the input TM mode will be supported in the strip waveguides and coupled to the adjacent HPWs due to phase matching and gradually attenuated via the metals. As a result, a compact TE-pass polarizer is realized. Results show that the proposed polarizer has a total coupling length of 6 µm, with an extinction ratio (ER) of 31.2 dB, insertion loss (IL) of 0.1 dB, and reflection loss (RL) of

−

26.2

d
B

at 1.55 µm, and its operation bandwidth can be up to 270 nm (from 1.43 to 1.7 µm) for

E
R

>

20

d
B

and

I
L

<

1

d
B

. In addition, fabrication tolerances to the key structural parameters and field evolution through the proposed device are given.
Single-mode spatiotemporal soliton attractor in multimode GRIN fibers
Authors: Zitelli M. , Ferraro M. , Mangini F. , Wabnitz S. 
Published: February 2021

Experimental and numerical studies of spatiotemporal femtosecond soliton propagation over up to 1 km spans of parabolic graded-index fibers reveal that initial multimode soliton pulses naturally and irreversibly evolve into a single-mode soliton. This is carried by the fundamental mode of the fiber, which acts as a dynamical attractor of the multimode system for up to the record value (for multimode fibers) of 5600 chromatic dispersion distances. This experimental evidence invalidates the use of variational approaches, which intrinsically require that the initial multimode propagation of a self-imaging soliton is indefinitely maintained.
Ideology and the Virtual City: Video games, Power Fantasies and Neoliberalism, Jon Bailes (2018)
Authors: Shelton James 
Published: February 2021

Review of: Ideology and the Virtual City: Video games, Power Fantasies and Neoliberalism, Jon Bailes (2018)
Winchester and Washington: Zero Books, 112 pp.,
ISBN 978-1-78904-164-4, p/bk, £9.99
Through the looking glass: Reflections of a writing scholar
Authors: Graham Steve 
Published: February 2021

The Acquired Wisdom series provides veteran academics, like myself, a soapbox from which to brandish their accomplishments, failures, and lessons they presumably learned. It can be foolish and maybe a tad dangerous to offer an old dog a platform from which to bark. But here we are. I will try my best not to be dangerous. I make no promises about folly and banality.Start at the BeginningIn the 1951 movie, Alice in Wonderland, the March Hare and the Mad Hatter give advice about how to tell a story – simply put: “Start at the beginning.” So here we go. (Hopefully the folly meter is not ticking upward yet.)
PENGARUH KEBIASAAN BERKENDARA TERHADAP PERILAKU BERKENDARA DAN ATRIBUT BERKENDARA DRIVER OJEK ONLINE (STUDI KASUS)
Authors: Susanto Novie , Mujahidin Esa Akhmad , Siswanto Siswanto 
Published: February 2021

Ojek online hadir ditengah banyaknya jumlah sepeda motor dengan melihat peluang bisnis ojek online. Jumlah kendaraan bermotor tiap tahunnya yang semakin meningkat menyebabkan jumlah kecelakaan yang terjadi dari tahun ke tahun juga ikut mengalami peningkatan. Menganalisis hubungan antara kebiasaan berkendara terhadap perilaku berkendara dan atribut berkendara merupakan langkah pencegahan kecelakaan pada driver ojek online. Penelitian ini menggunakan metode PLS (Partial Least Square) untuk menganalisis hubungan antara variabel kebiasaan berkendara terhadap perilaku dan atribut berkendara. Berdasarkan hasil pengujian dari metode PLS didapatkan kebiasaan berkendara memeiliki hubungan signifikan dengan t-stat 4,584 terhadap atribut berkendara. Variabel kebiasaan berkendara memiliki hubungan yang signifikan terhadap erilaku berkendara dengan t-stat 64,533. Perilaku berkendara memiliki hubungan yang signifikan terhadap atribut berkendara dengan nilai t-stat 3,567. Abstract[THE EFFECT OF DRIVING HABITS TO DRIVING BEHAVIOR AND DRIVING ATTRIBUTE OF ONLINE MOTORCYCLE TAXI DRIVERS (A CASE STUDY)] Online motorcycle taxi comes in the middle of the number of motorbikes by looking at the motorcycle taxi business opportunities online. The number of vehicles that are increasing every year which increases causing the number that occurs from year to year which also increases. Analyzing the relationship between driving while traffic and the attribute of riding traffic towards OJEK ONLINE drivers is one of effort to decrease the number of accidents. This study uses the PLS (Partial Least Square) method to analyze the relationship between driving habits variables on driving behavior and attributes. Based on the test results of the PLS method, it is showed that driving habits have a significant relationship with the t-stat 4,584 to the driving attributes. The driving habits variable has a significant relationship to driving behavior with t-stat 64,533. Driving behavior has a significant relationship to driving attributes with a t-stat value of 3.567. Keywords: driving habits; driving behavior; driving attributes; PLS; online motorcycle taxi
PENINGKATAN EFISIENSI PERSEDIAAN WORK IN PROCESS GREEN TYRE DI PT XYZ
Authors: Wijaya Hendri , Puspasari Luky 
Published: February 2021

Manajemen persediaan dapat meningkatkan kemampuan perusahaan untuk menghasilkan produk tepat waktu, dengan jumlah yang tepat, serta kualitas yang sesuai standar. PT XYZ adalah perusahaan yang menghasilkan produk ban tubless. Terdapat 8 proses untuk menghasilkan ban tubeless, dan masing-masing proses menghasilkan penyimpanan work in process. Salah satu dari work in process adalah green tyre. PT XYZ menghadapi masalah terjadi overstock pada green tyre yang menimbulkan produk cacat. Tujuan dari studi adalah untuk menentukan jumlah produksi yang tepat untuk mengatasi permasalahan overstock. Metode yang digunakan untuk menyelesaikan permasalahan ini adalah Economic Production Quantity (EPQ). Metode EPQ terbukti dapat mengurangi biaya penyimpanan dalam satu bulan sebesar Rp 33,218,117 atau sebesar 40% dari biaya semula. Alat penyimpanan juga dapat dikurangi sebesar 34%, serta luas area penyimpanan dapat dikurangi sebesar 14%. AbstractInventory management can increase a company's ability to produce products on time, with the correct amount and meet the quality standard. PT XYZ is a company that produces tubeless tyres. There are eight processes to produce the tubeless tyre, and each process results a work in process inventory. One of the process is a green tyre. PT XYZ faces the overstock of green tyre that raises the amount of the defect. The aim of this study was to determine the amount of production appropriately to avoid the overstock problem. Economic Production Quantity (EPQ) method was used to solve this problem. EPQ method decreased the inventory cost as much as IDR 33,218,117 or 40% of the existing inventory cost, and reduced storage tools of 34% and reduced the storage area of 14 %.Keywords: work in process; inventory; green tyre; overstock; eqonomic production quantity
REDESAIN TATA LETAK PRODUK DI SUPERMARKET BERDASARKAN PERILAKU PEMBELIAN DENGAN METODE MARKET BASKET ANALYSIS
Authors: Purwaningsih Ratna , Widharto Yusuf , Susanto Novie , Utami Listyorini Tri 
Published: February 2021

Lamanya pembeli swalayan mencari barang yang diperlukan mengurangi ketidaknyamanan. Jika jenis dan jumlah produk yang dicari cukup banyak dan letak produk - produk yang dibeli berjauhan, maka waktu di dalam ruang belanja akan semakin lama. Penelitian ini bertujuan untuk mensimulasikan penataan produk produk yang dijual di swalayan dengan mempertimbangkan perilaku konsumen yaitu kelompok produk yang dibeli berdasarkan data dari struk belanja. Metode yang digunakan adalah market basket analysis yang akan mengukur support factors dari kelompok produk dan menata produk yang harus didekatkan berdasarkan confident value. Hasil perhitungan Market Basket Analysis menemukan delapan pasang kelompok produk yang sebaiknya diletakkan berdekatan menurut nilai support factor. Kedekatan antar kelompok produk kemudian ditata menurut nilai confident value dan dilakukan validasi dengan mengukur nilai improvement rasio. Simulasi jarak yang harus ditempuh pengunjung setelah produk ditata sesuai dengan kelompok produk mendapatkan reduksi jarak 10 % dibanding penataan produk yang tidak mempertimbangkan kelompok produk. Abstract[Title: Redesign of Product Layout in Supermarket Based on Purchase Behavior used Market Basket Analysis Method] The length of time that self-service buyers search for the necessary item reduces inconvenience. If the types and quantities of product are large enough and the locations of the products are far apart, the shopping time will be longer. This study aims to simulate the arrangement of product sold in supermarkets by considering consumer behavior in purchased product groups based on data from shopping receipts. The method used is market basket analysis, which measures support factors from product groups and arranges that must be placed close together based on confident value. The calculation results of Market Basket Analysis found eight pairs of product groups that should be placed close together according to the high support factor value. The closeness between product groups is then arranged according to the confident value and validated by measuring the value of the improvement ratio. The simulation of the distance that visitors must travel after the product is arranged according to the product group has a 10% reduction in distance compared to the product arrangement that does not consider product groups.Keywords: product arrangement, supermarket, Market Basket Analysis
La main abstraite, analyse d’un élément polyfonctionnel en samba leko, langue Adamawa du Cameroun
Authors: Fabre Gwenaëlle 
Published: February 2021

Résumé
Comme bien d’autres langues isolantes, le samba leko dispose de morphèmes transcatégoriels et polyfonctionnels quelque peu déroutants pour le descripteur à la recherche de l’invariant sémantique supposé observable dans la variété de leurs emplois. On se propose ici, au travers des différentes attestations de ce terme dans le corpus textuel de première main, de traiter de l’élément na᷆ ∼ na᷄w que les locuteurs traduisent instinctivement ‘en main’, mais dont la signification dépasse largement cette valeur référentielle. Au travers des exemples, on verra que la possession aliénable, la temporalité et le contrôle semblent au cœur du sémantisme de cet élément.
The Contribution of Environmental Enrichment to Phenotypic Variation in Mice and Rats
Authors: Kentner Amanda C. , Speno Amanda V. , Doucette Joanne , Roderick Ryland C. 
Published: February 2021

AbstractThe reproducibility and translation of neuroscience research is assumed to be undermined by introducing environmental complexity and heterogeneity. Rearing laboratory animals with minimal (if any) environmental stimulation is thought to control for biological variability but may not adequately test the robustness of our animal models. Standard laboratory housing is associated with reduced demonstrations of species typical behaviors and changes in neurophysiology that may impact the translation of research results. Modest increases in environmental enrichment (EE) mitigate against insults used to induce animal models of disease, directly calling into question the translatability of our work. This may in part underlie the disconnect between preclinical and clinical research findings. Enhancing environmental stimulation for our model organisms promotes ethological natural behaviors but may simultaneously increase phenotypic trait variability. To test this assumption, we conducted a systematic review and evaluated coefficients of variation (CVs) between EE and standard housed mice and rats. Given findings of suboptimal reporting of animal laboratory housing conditions, we also developed a methodological reporting table for enrichment use in neuroscience research. Our data show that animals housed in EE were not more variable than those in standard housing. Therefore, environmental heterogeneity introduced into the laboratory, in the form of enrichment, does not compromise data integrity. Overall, human life is complicated, and by embracing such nuanced complexity into our laboratories, we may paradoxically improve on the rigor and reproducibility of our research.