bluuebunny/crossref_metadata_2025_split huggingface dataset:
Swallowing Exercise During Head and Neck Cancer Treatment: Results of a Randomized Trial
Authors: Hajdú Sara Fredslund , Wessel Irene , Dalton Susanne Oksbjerg , Eskildsen Signe Janum , Johansen Christoffer 
Published: June 2021

AbstractThe diagnosis and treatment of head and neck cancer (HNC) can have substantial impact on swallowing function, nutritional balance, physical function and quality of life (QoL). Early initiated swallowing exercises are hypothesized to improve swallowing function in HNC patients. The aim was to investigate the effects of swallowing exercises and progressive resistance training (PRT) during radiotherapy on swallowing function, physical function and QoL in patients with pharynx-, larynx-, oral cavity cancer or unknown primary compared to usual care. In a multi-centre RCT participants were assigned to (a) twice-weekly PRT and daily swallowing exercises throughout treatment or (b) usual care. Outcomes were measured at end of treatment and 2, 6 and 12 months after. Primary outcome was penetration aspiration score (PAS). Data were analysed on an “intention-to-treat” basis by GEE logistic regression model, linear mixed effects model and cox regression. Of 371 invited HNC patients, 240 (65%) enrolled. Five participants were excluded. At 12 months follow-up, 59 (25%) participants were lost. Analyses showed significant effect on mouth opening, QoL, depression and anxiety at 12 months when comparing intervention to non-active controls. The trial found no effect on swallowing safety in HNC undergoing radiotherapy, but several positive effects were found on secondary outcomes when comparing to non-active controls. The intervention period may have been too short, and the real difference between groups is too small. Nevertheless, the need to identify long-lasting intervention to slow down or avoid functional deteriorations is ever more crucial as the surviving HNC population is growing.
Closed non-suction drain placement as haematoma and seroma formation preventive measure post-nylon darn surgery for inguinoscrotal hernias in adults
Authors: Hagbevor Israel , Ali Mahamudu Ayamba , Awuku George Asare 
Published: June 2021

AbstractPurposeInguinal hernia is a common male surgical disease. Intervention carries a wide range of complications such as scrotal haematoma and seroma which may require surgical re-intervention or predispose patients to developing infections, pains or feeling of mass. This could lead to long hospital stay. Scrotal tamponade by bandaging or wearing of tight pants and elevation are practiced to reduce bleeding and haematoma formation. These methods require prolong use. Closed suction drains are scarcely used in resource-deprived communities due to high cost and non-availability.AimThis study was to determine the effectiveness of a closed non-suction drain in preventing scrotal collection requiring further surgical intervention and the predisposition to developing surgical site infection following nylon darn repair of inguinoscrotal hernia.MethodsForty (40) participants were recruited for a preliminary study and assigned into control and interventional groups (CG, IG) for purposes of inserting flexible feeding tube (FFT) wound drain after nylon darn (ND) repair. Daily measurement of drained scrotal collection was carried out in the IG till the day drainage was zero. Residual volumes in IG and wound collection in the CG who were not candidates for re-intervention were determined at 14th and 28th post-operative days using ultrasound scan. Data were analyzed using SPSS version 25.ResultsThree (3) patients (15.8%) in the CG required re-intervention. Surgical site infection rates for the CG and IG were, respectively, 2/19 versus 0/21 (ρ = 0.134).There was a numerical significant difference in the mean volumes of scrotal collections between the control (0.95 ± 0.42 ml) and the intervention group (0.44 ± 0.33 ml) [pvalue of 0.041] but with no clinical impact.ConclusionSimple inexpensive flexible feeding tube placement significantly reduced scrotal collection which forms a base for larger sample size in subsequent studies. This could reduce the feared risk of re-intervention, wound infection and long hospital stay post-operative.
Leveraging human factors in cybersecurity: an integrated methodological approach
Authors: Pollini Alessandro , Callari Tiziana C. , Tedeschi Alessandra , Ruscio Daniele , Save Luca , Chiarugi Franco , Guerri Davide 
Published: June 2021

AbstractComputer and Information Security (CIS) is usually approached adopting a technology-centric viewpoint, where the human components of sociotechnical systems are generally considered as their weakest part, with little consideration for the end users’ cognitive characteristics, needs and motivations. This paper presents a holistic/Human Factors (HF) approach, where the individual, organisational and technological factors are investigated in pilot healthcare organisations to show how HF vulnerabilities may impact on cybersecurity risks. An overview of current challenges in relation to cybersecurity is first provided, followed by the presentation of an integrated top–down and bottom–up methodology using qualitative and quantitative research methods to assess the level of maturity of the pilot organisations with respect to their capability to face and tackle cyber threats and attacks. This approach adopts a user-centred perspective, involving both the organisations’ management and employees, The results show that a better cyber-security culture does not always correspond with more rule compliant behaviour. In addition, conflicts among cybersecurity rules and procedures may trigger human vulnerabilities. In conclusion, the integration of traditional technical solutions with guidelines to enhance CIS systems by leveraging HF in cybersecurity may lead to the adoption of non-technical countermeasures (such as user awareness) for a comprehensive and holistic way to manage cyber security in organisations.
Semiautomatic robust regression clustering of international trade data
Authors: Torti Francesca , Riani Marco , Morelli Gianluca 
Published: June 2021

AbstractThe purpose of this paper is to show in regression clustering how to choose the most relevant solutions, analyze their stability, and provide information about best combinations of optimal number of groups, restriction factor among the error variance across groups and level of trimming. The procedure is based on two steps. First we generalize the information criteria of constrained robust multivariate clustering to the case of clustering weighted models. Differently from the traditional approaches which are based on the choice of the best solution found minimizing an information criterion (i.e. BIC), we concentrate our attention on the so called optimal stable solutions. In the second step, using the monitoring approach, we select the best value of the trimming factor. Finally, we validate the solution using a confirmatory forward search approach. A motivating example based on a novel dataset concerning the European Union trade of face masks shows the limitations of the current existing procedures. The suggested approach is initially applied to a set of well known datasets in the literature of robust regression clustering. Then, we focus our attention on a set of international trade datasets and we provide a novel informative way of updating the subset in the random start approach. The Supplementary material, in the spirit of the Special Issue, deepens the analysis of trade data and compares the suggested approach with the existing ones available in the literature.
Partition-based distributionally robust optimization via optimal transport with order cone constraints
Authors: Esteban-Pérez Adrián , Morales Juan M. 
Published: June 2021

AbstractIn this paper we wish to tackle stochastic programs affected by ambiguity about the probability law that governs their uncertain parameters. Using optimal transport theory, we construct an ambiguity set that exploits the knowledge about the distribution of the uncertain parameters, which is provided by: (1) sample data and (2) a-priori information on the order among the probabilities that the true data-generating distribution assigns to some regions of its support set. This type of order is enforced by means of order cone constraints and can encode a wide range of information on the shape of the probability distribution of the uncertain parameters such as information related to monotonicity or multi-modality. We seek decisions that are distributionally robust. In a number of practical cases, the resulting distributionally robust optimization (DRO) problem can be reformulated as a finite convex problem where the a-priori information translates into linear constraints. In addition, our method inherits the finite-sample performance guarantees of the Wasserstein-metric-based DRO approach proposed by Mohajerin Esfahani and Kuhn (Math Program 171(1–2):115–166. https://doi.org/10.1007/s10107-017-1172-1, 2018), while generalizing this and other popular DRO approaches. Finally, we have designed numerical experiments to analyze the performance of our approach with the newsvendor problem and the problem of a strategic firm competing à la Cournot in a market.
Cultural change and the migration choice
Authors: Lanati Mauro , Venturini Alessandra 
Published: June 2021

AbstractCultural differences play an important role in shaping migration patterns. The conventional proxies for cross country cultural differences, such as common language; ethnicity; genetic traits; or religion, implicitly assume that cultural proximity between two countries is constant over time and symmetric. This is far from realistic. This paper proposes a gravity model for international migration which explicitly allows for the time varying and asymmetric dimensions of cultural proximity. In accordance with Disdier, Tai, Fontagné, Mayer (Rev World Econ, 145(4):575–595, 2010) we assume that the evolution of bilateral cultural affinity over time is reflected in the intensity of bilateral trade in cultural goods. The empirical framework includes a comprehensive set of high dimensional fixed effects which enable identification of the impact of cultural proximity on migration over and beyond the effect of pre-existing cultural and historical ties. The results are robust across different econometric techniques and suggest that positive changes in cultural relationships over time foster bilateral migration.
Doctors as disseminators? Practicing physicians as multipliers for community-based prevention networks in a large city in western Germany
Authors: Kreffter Katharina , Götz Simon , Lisak-Wahl Stefanie , Nguyen Thuy Ha , Dragano Nico , Weyers Simone 
Published: June 2021

Abstract
Aim
Practicing physicians have a special position as disseminators of community-based prevention for children. However, it is unclear to what extent physicians inform parents about programs. The study investigated: To what extent do physicians disseminate information about community-based prevention for children aged 0–7? Do differences exist along family’s socioeconomic position (SEP) and immigrant background?

Subject and methods
We conducted a retrospective cohort study in a German school entrance examination. Parents were invited to participate in a survey on community-based prevention with information about their awareness and information source. SEP was measured by parental education, immigrant background by country of birth. For nine services types, we counted how often parents named physicians and other professional groups as information sources. To estimate social differences, we calculated adjusted odds ratios (OR) with 95% confidence interval (CI).

Results
Survey participants included 6480 parents (response 65.49%). Compared to other information sources, physicians were mentioned less frequently. For example, regarding language therapy, 31.2% of parents were informed by healthcare/social services, and 4.4% by physicians. Lower educated parents were less frequently informed by physicians about counseling services (OR 0.58; 95% CI 0.46–0.73) compared to higher educated parents. Parents with immigrant background were informed less often about parenting skills courses (OR 0.79; 95% CI 0.70–0.90) compared to parents without immigrant background, but more often about language therapy (OR 1.47; 95% CI 1.13–1.91). No further social differences were observed.

Conclusion
The role of physicians as disseminators for community-based prevention is expandable. They should promote parenting skills courses in a socially sensitive way.
Food Should not be Forgotten: Impacts of Combined Cash Transfer Receipt and Food Security on Child Education and Cognition in South Africa and Malawi
Authors: Sherr Lorraine , Roberts Kathryn J. , Tomlinson Mark , Skeen Sarah , Mebrahtu Helen , Gordon Sarah , du Toit Stefani , Haag Katharina , Cluver Lucie D. 
Published: June 2021

AbstractSocial protection can take many forms. Both cash transfers and food security may have important contributions to child cognitive development. This study examines the potential impact of combinations of cash transfers and food security status on child cognitive development and educational outcomes. Cross-sectional data for 796 HIV-affected children in the Child Community Care study were utilised for this analysis. Children and caregivers completed interview schedules comprised of standardised items on socio-demographics, household data, cash grant receipt and food security status, school achievement, and cognition. A series of logistic and linear regression models and marginal effects analyses were undertaken to explore the impacts of differing levels of social protection (none; either cash grant receipt or food secure status or, both in combination) on child educational and cognitive outcomes. Although all children lived in poverty-stricken households, 20% (157/796) of children did not live in a household in receipt of a cash grant and did not report food security; 32.4% (258/796) reported either component of social protection and, 47.9% (381/796) received both measures of social protection in combination. Compared to no social protection, being in receipt of either component of social protection was found to be significantly associated with being in the correct class for age, higher scores of non-verbal cognition, and higher working memory scores. Receiving both social protection measures in combination was found to be significantly associated with reduced educational risk scores, improved odds of being in the correct class for age, regular school attendance, missing less than a week of school in the previous two weeks, higher scores on measures of nonverbal cognition, higher working memory scores, and learning new things more easily. Educational and cognitive outcomes for children can be bolstered by social protection measures (cash grant receipt or food security). Benefits are enhanced when social protection is received in combination. Such findings support the notion of synergistic social protection responses for children living in environments impacted by high levels of HIV burden and deprivation.
Evaluation of microfiber release from jeans: the impact of different washing conditions
Authors: Periyasamy Aravin Prince 
Published: June 2021

AbstractMicroplastic particles are a burgeoning population crisis in the marine environment. This research examines the emission of microfibers from three different jeans (garments) during domestic washing. The jeans types, washing temperature, washing duration, spin speed, detergent types, and addition of conditioner are the main factors for this research work. The average length and diameter of the microfibers for the 100% PET jeans (jeans-P) has 7800 ± 4000 μm and 11.9±3.2 μm and for polyester/cotton jeans (jeans-PB) has 4900 ± 2200 μm 17.4±4.8 μm, respectively. The maximum microfiber released was observed in the rigorous washing treatment (90 min, 60°C, 1400 rpm, powder detergent with the presence of conditioner). The surmised number of microfibers discharged from the 1 kg wash load of jeans-P was calculated within the extent of 2300000–4900000 microfibers, and it is varied by the washing treatments.
Durability analysis of bio-cemented slope soil under the exposure of acid rain
Authors: Gowthaman Sivakumar , Nakashima Kazunori , Kawasaki Satoru 
Published: June 2021

Abstract
Purpose
Instability of slope surface is a critical concern in Geotechnical and Environmental Engineering. MICP (Microbial-Induced Carbonate Precipitation), an innovative bio-cementation technique, has attracted the attention for slope surface protection. In this work, MICP was investigated to evaluate its durability under the exposure of acid rain and to advance the understanding on long-term performance of slope soil preserved by MICP.

Methods
MICP treatment was applied to a fine-grained slope soil using indigenous bacteria. Specimens treated to different cementation levels (% CaCO3) were exposed to acid rain (of varying pH) through two sorts of mechanisms: (i) infiltration and (ii) immersion. The evaluations were based on corrosion of CaCO3, mass loss, needle penetration tests, and scanning electron microscopy.

Results
The decrease in pH increased the corrosion of CaCO3, resulting in considerable loss in aggregate and unconfined compressive strength. However, increased cementation level showed high durability of specimens. The soils treated to 12.5% CaCO3 showed 19.9% soil loss, whereas it was reduced to 5.4% when cemented to 22.5% CaCO3. The results also revealed that the contact time of acid rain significantly governed the rate of corrosion, i.e., specimens subjected to lower infiltration rate (20 mm/h) showed higher loss of mass compared to that of higher rate (100 mm/h).

Conclusion
The long-term performance of MICP treatment is determined by (i) cementation level, (ii) pH, and (iii) infiltration rate of acid rain. High cementation level promotes the longevity of the treatment. Therefore, MICP to higher cementation level is recommended for long-term preservation of slope surface.
Synthesis and Theoretical Investigation Using DFT of 2,3-Diphenylquinoxaline Derivatives for Electronic and Photovoltaic Effects
Authors: Zając Dorota , Przybylski Dariusz , Sołoducho Jadwiga 
Published: June 2021

AbstractDeveloping effective and low‐cost organic semiconductors is an opportunity for the development of organic solar cells (OPV). Herein, we report the molecular design, synthesis and characterization of two molecules with D–A–D–A configuration: 2-cyano-3-(5-(8-(3,4-ethylenodioxythiophen-5-yl)-2,3-diphenylquinoxalin-5-yl)thiophen-2-yl)acrylic acid (6) and 2-cyano-3-(5-(2,3-diphenyl-8-(thiophen-2-yl)quinoxalin-5-yl)thiophen-2-yl)acrylic acid (7). Moreover, we investigated the structural, theoretical and optical properties. The distribution of HOMO/LUMO orbitals and the values of the ionization potential indicate good semiconducting properties of the compounds and that they can be a bipolar material. Also, the optical study show good absorption in visible light (λabs 380–550 nm). We investigate the theoretical optoelectronic properties of obtained compounds as potential materials for solar cells.
Assessing genotyping errors in mammalian museum study skins using high-throughput genotyping-by-sequencing
Authors: Yuan Stella C. , Malekos Eric , Hawkins Melissa T. R. 
Published: June 2021

AbstractThe use of museum specimens held in natural history repositories for population and conservation genetic research is increasing in tandem with the use of massively parallel sequencing technologies. Short Tandem Repeats (STRs), or microsatellite loci, are commonly used genetic markers in wildlife and population genetic studies. However, they traditionally suffered from a host of issues including length homoplasy, high costs, low throughput, and difficulties in reproducibility across laboratories. Massively parallel sequencing technologies can address these problems, but the incorporation of museum specimen derived DNA suffers from significant fragmentation and exogenous DNA contamination. Combatting these issues requires extra measures of stringency in the lab and during data analysis, yet there have not been any high-throughput sequencing studies evaluating microsatellite allelic dropout from museum specimen extracted DNA. In this study, we evaluate genotyping errors derived from mammalian museum skin DNA extracts for previously characterized microsatellites across PCR replicates utilizing high-throughput sequencing. We found it useful to classify samples based on DNA concentration, which determined the rate by which genotypes were accurately recovered. Longer microsatellites performed worse in all museum specimens. Allelic dropout rates across loci were dependent on sample quantity, with high concentration museum specimens performing as well and recovering quality metrics nearly as high as the frozen tissue sample. Based on our results, we provide a set of best practices for quality assurance and incorporation of reliable genotypes from museum specimens.
The interaction and interference of preformed metal crowns on magnetic resonance imaging: a scoping review with a systematic methodology
Authors: Sumner O. , Goldsmith R. , Heath N. , Taylor G. D. 
Published: June 2021

Abstract
Purpose
Preformed metal crowns are widely used to restore primary and permanent teeth. Children may require magnetic resonance imaging (MRI) for diagnosis and monitoring of diseases in the head and neck region. Metallic objects, in the field of view, may compromise the diagnostic value of an MRI. The impact on the diagnostic quality of an MRI in children who have had preformed metal crowns placed has not been assessed. The aim of this systematic review was to evaluate the impact that PFMCs have on MRI imaging quality and thus the overall diagnostic value.

Methods
Electronic searches of the following databases were completed: MEDLINE, EMBASE, Cochrane Library, Web of Science and Open Grey. Primary in vivo studies on children who had at least one preformed metal crown placed and required an MRI investigation were to be included. PRISMA guidelines were followed and screening/data extraction was carried out by two independent calibrated reviewers.

Results
A total of 7665 articles were identified. After removing duplicates, 7062 were identified for title and abstract screening. Thirty-four articles underwent full-text review, of which none met the inclusion criteria. Most common reasons for exclusion were not placing preformed metal crowns (n = 16) or in vitro studies (n = 12).

Conclusion
No in vivo studies were identified to establish the hypothetical impact preformed metal crowns would have on the diagnostic quality of an MRI in the head and neck region. Decision making needs to be guided on a case by case basis. Further high-quality clinical studies are required.