bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accounting for both automated recording unit detection space and signal recognition performance in acoustic surveys: A protocol applied to the cryptic and critically endangered Night Parrot (Pezoporus occidentalis)
Authors: Leseberg Nicholas P. , Venables William N. , Murphy Stephen A. , Jackett Nigel A. , Watson James E. M. 
Published: December 2021

AbstractResearch into the suitability of autonomous recording units (ARUs) when surveying for vocal species is increasing. Simultaneously, there has been extensive research into methods for efficiently extracting signals of interest from the acoustic data sets that accrue from the deployment of ARUs. For some species, bioacoustic monitoring supported by computerised signal detection offers the only effective and efficient method for widespread survey. In these circumstances, the detection space of both the ARU and the performance of the signal detection process must be considered concurrently, but typically, these two elements have been considered separately. Here, using the Night Parrot (Pezoporus occidentalis) as a case study, we consider both ARU detection space and the signal detection process to develop a robust and repeatable survey protocol for the species. After developing a call recogniser for the Night Parrot, we test its performance on a data set of Night Parrot calls given at a known distance from an array of ARUs. Having established a relationship between ARU type, recogniser performance and distance, we determine the sampling radius of an ARU for a given recogniser score cut‐off, and the associated probability of detecting a Night Parrot that calls within that sampling radius. Using these data, we outline how to develop a robust and repeatable survey protocol for the Night Parrot, with a defined probability of detection. This protocol could be adapted for other scenarios where deployment of ARUs is necessary to determine a species’ status and distribution.
A potential diagnostic pitfall in ST elevation: Acute pulmonary embolism or ST‐segment elevation myocardial infarction
Authors: Zheng Bo , Bian Fei , Li Jingsen , Xu Huipu , Wang Jian 
Published: December 2021

AbstractThe diagnosis of acute pulmonary embolism (APE) is a great challenge for physicians due to its nonspecific symptoms, and often missed or misdiagnosed as acute coronary syndrome. Electrocardiographic (ECG) abnormalities are seen in majority of patients with APE. Recently, APE with ST‐segment elevation (STE) in leads V1–V3/V4, mimicking ST‐segment elevation myocardial infarction (STEMI), has been described. However, coronary angiography showed that the patient's coronary arteries were mostly normal. Herein, we describe a case of APE presenting with STE in V1–V4, along with severe stenosis of the left anterior descending (LAD) artery.
Non‐synonymous alterations in AKR7A3 and ABCA6 correlate with bleeding in aged patients treated with rivaroxaban
Authors: Zhao Ming , Zhang Qiang , Wang Xizi , Zhang Qianqian , Tian Conghui , Li Rongrong , Jia Xiaodong , Gu Mingliang , Yang Liping 
Published: December 2021

AbstractRivaroxaban is an oral anticoagulant that inhibits thrombin and blocks coagulation cascade through directly inactivating factors Xa. Despite rivaroxaban is widely used for prevention and treatment of venous thrombosis, and its common adverse reactions have been reported, including abnormal coagulation, mucosal hemorrhage, hematuria, and intracranial hemorrhage. To explore potential drivers of individual differences in adverse reactions induced by rivaroxaban, we performed whole‐exome sequencing and found that AKR7A3 rs1738023/rs1738025 and ABCA6 rs7212506 are susceptible sites for rivaroxaban‐related bleeding in aged patients treated with rivaroxaban. Gene functional annotation and signaling pathway enrichment indicated that homozygous mutations in AKR7A3 and ABCA6 might alter normal rivaroxaban transport and metabolism, and lead to continuous accumulation of activated drugs and toxic substances in vivo. Our results suggested that interindividual differences in bleeding events induced by rivaroxaban may be potentially driven by genetic alterations related to abnormal metabolism and transport of rivaroxaban.
When long appears short: Effects of auditory distraction on event‐related potential correlates of time perception
Authors: Getzmann Stephan , Arnau Stefan , Gajewski Patrick D. , Wascher Edmund 
Published: December 2021

AbstractAttentional models of time perception assume that the perceived duration of a stimulus depends on the extent to which attentional resources are allocated to its temporal information. Here, we studied the effects of auditory distraction on time perception, using a combined attentional‐distraction duration‐discrimination paradigm. Participants were confronted with a random sequence of long and short tone stimuli, most of which having a uniform (standard) pitch and only a few a different (deviant) pitch. As observed in previous studies, pitch‐deviant tones impaired the discrimination of tone duration and triggered a sequence of event‐related potentials (ERPs) reflecting a cycle of deviance detection, involuntary attentional distraction and reorientation (MMN, P3a, RON). Contrasting ERPs of short and long tone durations revealed that long tones elicited a more pronounced fronto‐central contingent negative variation (CNV) in the time interval after the expected offset of the short tone as well as a more prominent centro‐parietal late positive complex (LPC). Relative to standard‐pitch tones, deviant‐pitch tones especially impaired the correct discrimination of long tones, which was associated with a reduction of the CNV and LPC. These results are interpreted within the theoretical framework of resource‐based models of time perception, in which involuntary distraction due to a deviant event led to a withdrawal of attentional resources from the processing of time information.
Relationship satisfaction among spouse caregivers of service members and veterans with comorbid mild traumatic brain injury and post‐traumatic stress disorder
Authors: Brickell Tracey A. , French Louis M. , Varbedian Nicole V. , Sewell Jessie M. , Schiefelbein Faith C. , Wright Megan M. , Lange Rael T. 
Published: December 2021

AbstractThis study examined relationship satisfaction and health‐related quality of life (HRQOL) among spouse caregivers assisting service members and veterans (SMV) with comorbid uncomplicated mild traumatic brain injury (MTBI) and post‐traumatic stress disorder (PTSD). Spouse caregivers (N = 205) completed the Couples Satisfaction Index (CSI), 12 HRQOL measures, and the Mayo‐Portland Adaptability Inventory 4th Edition (MPAI‐4). T‐scores were classified as “clinically elevated” using a cutoff of ≥60T. The sample was also classified into “Satisfied” (≥13.5, n = 113, 55.0%) or “Dissatisfied” (<13.5, n = 92, 44.0%) relationship categories. Using stepwise regression analysis, Anxiety, Family Disruption, Vigilance, Emotional Support, Feeling Trapped, and MPAI‐4 Adjustment were identified as the strongest predictors of CSI total scores (p < 0.001), accounting for 41.6% of the variance. Squared semi‐partial correlations revealed that 18.1% of the variance was shared across all six measures, with 7.8% to 1.5% of unique variance accounted for by each measure separately. When comparing the number of clinically elevated measures simultaneously, the Dissatisfied group consistently had a higher number of clinically elevated scores compared to the Satisfied group (e.g., 3‐or‐more clinically elevated scores: Dissatisfied = 40.2%, Satisfied = 8.8%, OR = 6.93, H = 0.76). Caring for a SMV with comorbid TBI and PTSD can have a profound impact on the spouse caregiver's HRQOL, relationship satisfaction, and family functioning. The findings from the current study continue to support the need for family involvement in the SMV’s treatment plan, but more effort is needed to integrate behavioral health treatment that focuses on the family member's own issues into military TBI and PTSD systems of care.
Oral health status and associated factors among Sudanese older adults: A cross‐sectional study
Authors: Salih Mayson Ahmed , Ali Raouf Wahab , Nasir Elwalid Fadul 
Published: December 2021

AbstractObjectivesThe aim was to assess the oral health status, prosthetic needs and the associated factors among older adults living in Khartoum State, Sudan.BackgroundUnderstanding the extent of the oral health problems and the associated factors in the older population is important for the determination of treatment needs and future planning of dental services.Materials and MethodsA cross‐sectional study among individuals ≥60 years attending Health Care Centers. Two calibrated examiners examined participants according to the WHO oral health examination form for adults. DMFT, periodontal conditions, oral mucosal lesions, tooth wear, prosthetic status and prosthetic needs were reported. Risk indicators investigated include age, gender, socioeconomic status, general health, oral hygiene practices, tobacco use and utilisation for dental services.ResultsTwo hundred forty‐nine older adults participated in the study, and 64.3% were males. The mean age was 68.4 years (SD ±6.7). The mean DMFT was 15.9 (SD ±9.1), with 85.3%, 94.8% and 19.3% of the participants having decayed, missing or filled teeth respectively. Periodontal pockets were present in 41.9%, mucosal lesions in 14.9% and tooth wear in 46.2% of the participants. Although only 5.2% were completely edentulous, 93.2% need prosthetic replacement. Risk indicators for poor oral health were being female, oral hygiene practices, frequency and reason of dental visits.ConclusionOld adults showed a high experience of missing and decayed teeth, periodontal inflammation and prosthetic treatment needs. Future oral health policies need to consider the different needs between men and women, exposure to risk factors and barriers to access dental care.
A femin… manifesto: Academic ecologies of care and cure during a global health pandemic
Authors: Benozzo Angelo , Koro Mirka , Vasquez Anani , Vitrukh Mariia , Barbetta Pietro , Long Charlton 
Published: December 2021

AbstractThis article is a femin… manifesto for supporting and encouraging academic ecologies of care and cure: it is a collaborative assemblage created by six academics—laborers, white, native American, European, Caucasian, cisgender, neurodivergent, bisexual, gay, and… and… and…—who wrote these reflections during the pandemic events that affected their lives. The cultural artifact, the femin… manifesto, is organized around nine theses, each of which tries to highlight the multiplicity of cares and genders, the challenges, the productive vitality, and the enforced slowness experienced both during lockdown and after it. The paper uses different forms/styles—academic writing, pictures, poems, first‐person narratives—which nurture the flow of the presentation of the nine theses. Each thesis ends with a call for action. The femin… manifesto is a performative text which, while opposing the constraints of the COVID‐19 emergency, also sees the potential the event offers for caring and curing ‐ both life and our academic lives. Femin… manifesto renders explicit the undecidability of cares and cures and is a call to unite with the aim of resisting the inequalities and vulnerabilities which COVID‐19 has exacerbated.
Distributed Thermal Response Multi‐Source Modeling to Evaluate Heterogeneous Subsurface Properties
Authors: Liu Honglei , Stumpf Andrew J. , Lin Yu‐Feng F. , Liu Xiaobing 
Published: December 2021

AbstractA thorough assessment of thermal properties in heterogeneous subsurface is necessary in design of low‐temperature borehole heat exchangers (BHEs). A distributed thermal response test (DTRT), which combines distributed temperature sensing (DTS) with a conventional thermal response test (TRT), was conducted in a U‐bend geothermal loop installed in an open borehole at the University of Illinois at Urbana‐Champaign to estimate thermal properties by analyzing the thermal response of different geologic materials while applying a constant heat input rate. Fiber‐optic cables in the DTRT were deployed both inside the U‐bend geothermal loop and in the center of the borehole to improve the accuracy of calculated heat‐loss rates and borehole temperature profile measurements. To assess the subsurface thermal conductivity during the heating phase of the DTRT, a single‐source model and a multi‐source model, both based on the infinite line source method, were developed using the borehole temperature data and temperatures inside and along the outside of the loop, separately. The two models returned similar thermal conductivity values. The multi‐source modeling has the advantage of predicting the thermal conductivity of heterogeneous geologic materials from borehole temperature profiles during the DTRT heating phase. In addition, based on the distributed thermal conductivity measured in the borehole, estimates were made for both radial thermal impacts and the rate of heat loss in the BHE.
U–Pb dating of detrital zircon from Permian successions of the South Kitakami Belt, Northeast Japan: Clues to the paleogeography of the belt
Authors: Li Yuxiao , Takeuchi Makoto 
Published: December 2021

AbstractThe South Kitakami Belt in the northeast Japan is unique in presence of a thick Paleozoic–Mesozoic sedimentary rocks. The Permian sedimentary succession in the Maiya area of this belt is divided into the Nishikori, Tenjinnoki, and Toyoma formations, in ascending stratigraphic order. The Tenjinnoki Formation includes the Yamazaki Conglomerate Member containing granitic clasts. We performed U–Pb dating for detrital zircon of one sample of tuffaceous sandstone from the Nishikori Formation, six samples of sandstone from the Tenjinnoki and Toyoma formations, and five granitic clasts from the Yamazaki Conglomerate using laser ablation‐inductively coupled plasma‐mass spectrometry. Our dating results show that the tuffaceous sandstone sample has two age peaks at 287 and 301 Ma for the Nishikori Formation, three age peaks at 320–300, 290, and 270 Ma for the Tenjinnoki and Toyoma Formation, and ages of 311, 300, and 270 Ma from granitic clasts of the Yamazaki Conglomerate. In addition, older ages of 452–435 and 380 Ma were obtained from some zircon grains of the sandstone and granitic clasts. Our results suggest igneous activity in these periods. The South Kitakami Belt's origin with respect to continental blocks has been discussed in regard of the margin of North China Block or South China Block. Based on the stratigraphic ages and timing of igneous activity, we conclude that during the Permian the South Kitakami Belt was located at the margin of the South Central Asian Orogenic Belt, near the Solonker‐Xra Moron‐Changchun suture and the North China Block in East Asia.
Consumer e‐waste disposal behaviour: A systematic review and research agenda
Authors: Gilal Faheem Gul , Shah Syed Mir Muhammad , Adeel Sultan , Gilal Rukhsana Gul , Gilal Naeem Gul 
Published: December 2021

AbstractE‐waste is the world's fastest‐growing waste stream, and it contains toxic chemicals that are harmful to human health. Research has shown that the vast majority of consumers are unwilling to dispose of e‐waste, preferring to keep obsolete products at home rather than returning them to manufacturers for recycling. Despite the evident importance of this area of research, there is yet to be a systematic assessment of e‐waste disposal behaviour that summarises the relationships among constructs in the forms of antecedents, decisions, and consequences from the perspective of consumer behaviour. With this knowledge gap in mind, the current paper's goal is to provide a comprehensive examination of available studies on consumer e‐waste disposal behaviour. In particular, the purpose is to promote e‐waste disposal behaviour by looking at how such behaviour has been utilised as a construct in the literature and what theories, contexts, characteristics, and methodological approaches have been used to strengthen this behaviour. Towards this aim, we used VOSviewer to examine N = 43 research publications on e‐waste disposal behaviour published in Scopus‐indexed journals between 2000 and 2021, noting discrepancies, identifying major research gaps, and developing comprehensive research agendas (provided in the form of testable propositions).
La conformité sociale, une pratique rentable? Pourquoi on peine à convaincre. Analyse sous l'angle des coûts, des bénéfices et du prix de vente
Authors: ANTOLIN Ana , BABBITT Laura , BROWN Drusilla 
Published: December 2021

RésuméPour améliorer les conditions de travail au sein des chaînes de valeur mondiales, il faudrait convaincre les directeurs d'usine que c'est une opération rentable, ce que plusieurs études ont établi. L'analyse, qui porte sur un échantillon d'usines appliquant le programme Better Work en Indonésie, en Jordanie et au Viet Nam, montre que le coût de la mise aux normes annule parfois les gains de productivité. Pour que l'opération soit rentable, il faut que les clients revoient leurs pratiques d'achat et acceptent de payer mieux. L'expérience du COVID‐19 confirme du reste l'influence déterminante des acheteurs sur les conditions de travail dans l'amont de la chaîne.
Introducción. Disrupciones en las cadenas mundiales de valor: ¿continuidad o cambio para la gobernanza laboral?
Authors: GEREFFI Gary , POSTHUMA Anne Caroline , ROSSI Arianna 
Published: December 2021

ResumenLa producción y el comercio mundiales organizados en cadenas mundiales de valor determinan la gobernanza del trabajo y las condiciones en que en ellas se ejerce desde hace décadas. Desde principios de los años 2000 se están produciendo perturbaciones económicas, tecnológicas y políticas, incluida la actual pandemia por COVID‐19, que exacerban las grandes preocupaciones en torno a la gobernanza y al futuro del trabajo en la economía mundial. Los artículos del presente monográfico abordan estos temas mediante estudios de caso originales sobre industrias y países, con diseños de investigación tanto longitudinales como comparativos y métodos mixtos para ofrecer perspectivas sobre un marco de gobernanza laboral que se adapte a las futuras cadenas mundiales de valor.
T cell activation niches—Optimizing T cell effector function in inflamed and infected tissues*
Authors: Bala Noor , McGurk Alexander I. , Zilch Tiago , Rup Anastasia N. , Carter Evan M. , Leddon Scott A. , Fowell Deborah J. 
Published: December 2021

AbstractSuccessful immunity to infection, malignancy, and tissue damage requires the coordinated recruitment of numerous immune cell subsets to target tissues. Once within the target tissue, effector T cells rely on local chemotactic cues and structural cues from the tissue matrix to navigate the tissue, interact with antigen‐presenting cells, and release effector cytokines. This highly dynamic process has been “caught on camera” in situ by intravital multiphoton imaging. Initial studies revealed a surprising randomness to the pattern of T cell migration through inflamed tissues, behavior thought to facilitate chance encounters with rare antigen‐bearing cells. Subsequent tissue‐wide visualization has uncovered a high degree of spatial preference when it comes to T cell activation. Here, we discuss the basic tenants of a successful effector T cell activation niche, taking cues from the dynamics of Tfh positioning in the lymph node germinal center. In peripheral tissues, steady‐state microanatomical organization may direct the location of “pop‐up” de novo activation niches, often observed as perivascular clusters, that support early effector T cell activation. These perivascular activation niches appear to be regulated by site‐specific chemokines that coordinate the recruitment of dendritic cells and other innate cells for local T cell activation, survival, and optimized effector function.
Skin‐ny deeping: Uncovering immune cell behavior and function through imaging techniques*
Authors: Tan Yingrou , Tey Hong Liang , Chong Shu Zhen , Ng Lai Guan 
Published: December 2021

AbstractAs the largest organ of the body, the skin is a key barrier tissue with specialized structures where ongoing immune surveillance is critical for protecting the body from external insults. The innate immune system acts as first‐responders in a coordinated manner to react to injury or infections, and recent developments in intravital imaging techniques have made it possible to delineate dynamic immune cell responses in a spatiotemporal manner. We review here key studies involved in understanding neutrophil, dendritic cell and macrophage behavior in skin and further discuss how this knowledge collectively highlights the importance of interactions and cellular functions in a systems biology manner. Furthermore, we will review emerging imaging technologies such as high‐content proteomic screening, spatial transcriptomics and three‐dimensional volumetric imaging and how these techniques can be integrated to provide a systems overview of the immune system that will further our current knowledge and lead to potential exciting discoveries in the upcoming decades.
Mutational spectrum of congenital long QT syndrome in Turkey; identification of 12 novel mutations across KCNQ1, KCNH2, SCN5A, KCNJ2, CACNA1C, and CALM1
Authors: Akgun‐Dogan Ozlem , Ağaoğlu Nihat B. , K. Demirkol Yasemin , Doğanay Levent , Ergül Yakup , Karacan Mehmet 
Published: December 2021

AbstractIntroductionLong QT syndrome (LQTS) is of great importance as it is the most common cause of sudden cardiac death in childhood. The diagnosis is made by the prolongation of the QTc interval on the electrocardiography. However, clinical heterogeneity and nondiagnostic QTc intervals may cause a delay in the diagnosis. In such cases, genetic tests such as next‐generation sequencing (NGS) panel analysis enable a definitive diagnosis. We present the first study that aimed to expand the LQTS's mutational spectrum by NGS panel analysis from Turkey.MethodsFifty‐seven unrelated patients with clinically diagnosed LQTS were investigated using an NGS panel that includes six LQTS‐related genes. Clinical aspects, outcome, and molecular analysis results were reviewed.ResultsPathogenic (53%)/likely pathogenic (23%)/variant of unknown significance (4%) variants were detected in any of the genes examined in 79% of the patients. Among all detected variants, KCNQ1(71%) was the most common gene, followed by SCN5A (11%), KCNH2 (10%), CALM1 (5%), and CACNA1C (3%). Twelve novel variants were detected. Among the variants in KCNQ1, the c.1097G>A variant was present in 42% of patients. This variant also composed 31% of the variants detected in all of the genes.ConclusionOur study expands the spectrum of the variations associated with LQTS with twelve novel variants in five genes. And also it draws attention to the frequency of the KCNQ1 c.1097G>A variant and forms the basis for new studies to determine the possible founder effect in the Turkish population. Furthermore, identifying new variants and clinical findings has importance in elaborating the roles of related genes in pathophysiology and determining the variable expression and incomplete penetration rates in this syndrome.