bluuebunny/crossref_metadata_2025_split huggingface dataset:
Certain issues relating to the calculation of the time spent in detention and the calculation of sentences for convicted prisoners detained in the penal correction detention centre
Authors: Алфимова Ольга Александровна 
Published: November 2021

В статье освещается правовая регламентация вопросов, связанных с исчислением сроков наказания и их зачета в отношении осужденных к лишению свободы, оставленных в следственных изоляторах уголовно-исполнительной системы. На сегодняшний день ст. 72 УК РФ в новой редакции не учитывает такую категорию осужденных, которые в порядке ст. 77 УИК РФ были оставлены в СИЗО (или тюрьме) для выполнения работ по хозяйственному обслуживанию. Еще одним проблемным вопросом в части положений ст. 72 УК РФ в новой редакции является то, что законодатель не учитывает тяжесть совершенного преступления и наличие рецидива в отношении осужденных к лишению свободы женщин. При зачете таким женщинам времени содержания под стражей в срок наказания правоприменитель должен руководствоваться более льготным положением п. «б» ч. 3.1 ст. 72 УК РФ (из расчета 1:1,5), а не 1:1, как у мужчин согласно п. «а» ч. 3.1 ст. 72 УК РФ. Такое «двойное смягчение» закона в отношении осужденных женщин продиктовано, как мы полагаем, принципом гуманизма. Однако в данном случае он нивелирует другие не менее важные принципы уголовного и уголовно-исполнительного законодательства, такие как справедливость, равенство перед законом и законность.
This article covers the legal regulation of issues related to the calculation of sentences and their set-off in respect of convicted persons to deprivation of liberty left in remand centres of the penal correction system. To date, Art. 72 of the Criminal Code of the Russian Federation, in its new version, does not take into account such a category of convicts who, in accordance with Art. 77 of the Code of Criminal Procedure of the Russian Federation, were left in a pre-trial detention center (or prison) for the performance of economic maintenance works. Another problematic issue in the part of the provisions of Art. 72 of the Criminal Code of the Russian Federation in the new version, in our opinion, is that the legislator does not take into account the gravity of the crime committed and the presence of recidivism against convicted women to the deprivation of liberty of women. When such women are credited with the time of detention during their sentence, the law enforcement officer should be guided by the more preferential provision of paragraph (b) of paragraph 3.1 Art. 72 of the Criminal Code of the Russian Federation (on the basis of 1:1.5), not 1:1 as in men according to item “a” of Pt 3.1 Art. 72 of the Criminal Code of the Russian Federation. This “double easing” of the law for convicted women is dictated, we believe, by the principle of humanism. However, in this case, it equalizes other equally important principles of criminal and penal enforcement legislation, such as justice, equality before the law and the rule of law.
PROTEOFIT: healthy, fit muscle cells for exercise and obesity prevention
Authors: Bartelt Alexander , Lemmer Imke 
Published: November 2021

PROTEOFIT: healthy, fit muscle cells for exercise and obesity prevention
Physical activity and exercise have beneficial effects on overall fitness and health. However, exercise-induced increases in metabolism require specific molecular adaptation of the muscle cells. This project aims to understand the molecular processes in the muscle during the adaptation to cold, exercise, and obesity, thereby defining novel mechanisms of protein homeostasis with regard to the gene switch Nfe2l1.
ESTUDO EXPERIMENTAL DO EFEITO DA MANIPULAÇÃO NA COARTICULAÇÃO NA PERCEPÇÃO DE CONSOANTES E VOGAIS DO PORTUGUÊS BRASILEIRO
Authors: Brito Dyuana Darck Santos 
Published: November 2021

A coarticulação é um fenômeno comum em todas as línguas, é peculiar à fala e apresenta caraterísticas distintas entre os falares (ÖHMAN, 1967 e FARNETANI, 1997 apud OLIVEIRA, 2000), porém, é um fenômeno ainda pouco estudado. Por outro lado, a percepção da fala é um campo complexo dentro dos estudos em fonética/fonologia, e visa a compreensão dos mecanismos acústicos e articulatórios por meio dos quais somos capazes de perceber os sons. Nesse trabalho, investiga-se, portanto, o efeito da manipulação da coarticulação na percepção em se tratando de consoantes obstruintes e das vogais [a], [i], [u], no português brasileiro. Para isso, manipulamos o sinal acústico dos monossílabos formados por esses segmentos, pela estrutura silábica CV, em três condições experimentais que foram submetidas a testes de identificação e de discriminação da percepção. Os resultados do teste de identificação apontam que as consoantes fricativas são mais facilmente percebidas que as consoantes oclusivas quando da manipulação do sinal acústico. E para o teste de discriminação, os resultados apontam que a depender da condição experimental, os juízes podem ou não ser sensíveis ao efeito da coarticulação na percepção.

Como citar:
BRITO, Dyuana Darck Santos. Estudo experimental do efeito da manipulação da coarticulação na percepção de consoantes e vogais do português brasileiro. Orientadora: Vera Pacheco; coorientadora: Maria de Fátima de Almeida Baia. 2016. 68f. Dissertação (mestrado em Linguística) – Universidade Estadual do Sudoeste da Bahia, Programa de Pós-graduação em Linguística, Vitória da Conquista, 2016. DOI: https://doi.org/10.54221/rdtdppglinuesb.2016.v4i1.75 . Acesso em: xxxxxxxx
A CATEGORIA VERBAL EM INTERLÍNGUA PORTUGÊS-LIBRAS: AQUISIÇÃO DA MODALIDADE ESCRITA DO PORTUGUÊS POR SURDOS
Authors: Silva Joyce Maria Sandes da 
Published: November 2021

O presente estudo objetiva investigar a categoria verbal no processo de aquisição da escrita do português por surdos brasileiros e pontuar os possíveis obstáculos que permeiam esse processo, considerando a língua brasileira de sinais (Libras), na modalidade falada, como a primeira língua (L1) dos surdos e o português, na modalidade escrita, como a língua alvo (L2). A partir de metodologia de análise de amostras de produção natural de língua escrita, procuramos descrever e analisar as ocorrências verbais convergentes e não convergentes com o PB encontradas em produções textuais de alunos surdos, a fim de compreender melhor o processo de aquisição da escrita de língua oral por surdos e ampliar o olhar sobre os problemas gramaticais de tais produções e possíveis reflexos da Libras sobre os mesmos. Conduzimos nossa investigação a partir de três hipóteses: (1) assumimos, conforme Kato (2005), que a aquisição da modalidade escrita é um processo de segunda ordem que se dá de forma muito similar ao processo de segunda língua (L2); (2) assumimos, ancoradas em Selinker (1972), a hipótese da interlíngua, de acordo com a qual a interlíngua, embora tenha em si propriedades inerentes tanto à língua materna quanto à língua alvo, difere sistematicamente de ambas as línguas; (3) com base no conjunto de traços de Cowper (2003), discutido por Freitag (2005), formulamos a hipótese de que a aquisição imperfeita do traço [Evento], relativamente ao sistema do português, seja a principal causa da falta de convergência entre os dados da interlíngua e a estrutura do português em sua modalidade escrita. A análise dos dados de interlíngua escrita produzidos pelos sujeitos-informantes nos permitiu constatar a naturezade estruturas gramaticais não convergentes com o PB frequentemente encontradas em produções textuais de surdos brasileiros aprendizes de português como L2. Verificamos que a natureza gramatical de tais problemas envolve desde a escolha lexical do verbo com traços mais apropriados até a composição da estrutura argumental, no que se refere ao número de argumentos e à seleção categorial.

Como citar:
SILVA, Joyce Maria Sandes da. A categoria verbal em interlíngua Português-Libras: aquisição da modalidade escrita do português para surdos. Orientadora: Adriana Stella Caroso Lessa-de-Oliveira. 2016 128f. Dissertação (mestrado em Linguística) – Universidade Estadual do Sudoeste da Bahia, Programa de Pós-graduação em Linguística, Vitória da Conquista, 2016. DOI: https://doi.org/10.54221/rdtdppglinuesb.2016.v4i1.86. Acesso em: xxxxxxxx
Jurisprudent Lucije Neracije Prisk / The Jurisprudent Lucius Neratius Priscus
Authors: Aličić Samir 
Published: November 2021

Politician and jurist which for a while, most probably in the periode between 102 and 106 a. D., performed function of administrator of Province of Pannonia. He was a renewned legal expert and member of Imperial council (consilium principis). As a student of Celsus the Elder, he was after his death, together with Celsus the Younger, leader of the Proculean legal school of thought. The biggest influence on him had Labeo, but he’s also closelly related to a less known jurisprudent Aristo. He gaved a big importance to legal rules and moral principles, and was under influence of both italic moralist tradition and stoic philosophy.
Rudarski propisi klasičnog i postklasičnog rimskog prava / Mining regulations of classical and postclassical Roman law
Authors: Drino Dževad , Londrc Benjamina 
Published: November 2021

In order to understand the functioning of mining in ancient Rome, it is necessary to investigate the rules of classical and post-classical Roman law related to mines. Most of the mining information is extracted from the Lex Vipasca, the two bronze plates found in Aljustrelo in Portugal in 1876 and 1906. The first plate from Aljustrelo provided valuable information on the mining sale taxes, the auctioneer’s provision, the management of baths, shoemakers, barbers, metallurgy workers, mining waste tax, teachers and seizure of mines and receivables. The second plate from Aljustrelo defines the responsibilities of the procurator, the rights and obligations of the owner, the price of the mine, and tells us about the way of organizing the leaseholders in societies – societas. From the preserved provision of Codex Theodosianus (CTh.X.19.8.) we learn about the existence of specially separated rights related to the mining and exploitation rights. The aim of our work is, through analysis of the Aljustrelo plates, to show how far Roman law has defined all aspects of mining in detail and to show the functioning of the system starting from the formation, acquisition of property, business, control, disputes, and associated activities that were formed with mines. These two plates with Roman mining laws provide an inexhaustible study-basis for lawyers, as well as others dealing with Ancient Rome. In addition to the mentioned Lex Vipasca, some minor and later mining regulations have been briefly outlined to complement the picture of Roman mining law.
‘Casualty of public health’: enige gedachten over compensatie van vaccinatieschade naar aanleiding van het Amerikaanse systeem
Authors: Haazen I. 
Published: November 2021

‘Casualty of public health’: enige gedachten over compensatie van vaccinatieschade naar aanleiding van het Amerikaanse systeem
Een gegarandeerde beschikbaarheid van innovatieve vaccins is onmisbaar in een wereld waar levensbedreigende infectieziekten steeds vaker voorkomen. Het risico dat vaccins bijwerkingen hebben en tot letsel leiden is daarbij onvermijdelijk. Het verhalen van vaccinatieschade via het aansprakelijkheidsrecht blijkt gecompliceerd. De auteur onderzoekt alternatieve systemen voor vergoeding van schade door vaccinaties. Vertrekpunt daarbij is Amerikaans onderzoek op dit terrein. Zij concludeert dat een no-faultschadefonds met een gedeeltelijke immuniteit van vaccinproducenten de meest geschikte weg is om vaccinatieschade te vergoeden zonder dat de ontwikkeling van vaccins in gevaar komt. De auteur doet enkele suggesties over de invulling van een dergelijk fonds.
Boltzmann Populations of the Fluxional Be6B11− and Chiral Be4B8 Clusters at Finite Temperatures Computed by DFT and Statistical Thermodynamics
Authors: Emilano Buelna-Garcia Carlos , Castillo-Quevedo Cesar , Paredes-Sotelo Edgar , Martinez-Guajardo Gerardo , Luis Cabellos Jose 
Published: November 2021

Total energy computations using density functional theory are typically carried out at a zero temperature; thus, entropic and thermic contributions to the total energy are neglected, even though functional materials work at finite temperatures. This book chapter investigates the Boltzmann populations of the fluxional Be6B11− and chiral Be4B8 isomers at finite temperature estimated within the framework of density functional theory, CCSD(T), and statistical thermodynamics. A couple of steps are taken into account to compute the Boltzmann populations. First, to identify a list of all possible low-energy chiral and achiral structures, an exhaustive and efficient exploration of the potential/free energy surfaces is carried out using a multi-level and multi-step global hybrid genetic algorithm search coupled with Gaussian code. Second, the thermal or so-called Boltzmann populations were computed in the framework of statistical thermodynamics for temperatures ranging from 20 to 1500 K at DFT and CCSD(T) theoretical levels. The results show the effects of temperature on the distribution of isomers define the putative global minimum at finite temperature due to the minimization of the Gibbs free energy and maximization of entropy. Additionally, we found that the fluxional Be6B11− cluster is strongly dominant at hot temperatures, whereas the chiral Be4B8 cluster is dominant at room temperature. The methodology and results show the thermal effects in the relative population hence molecular properties.
Fast Track Arthroplasty Using Local Infiltration Analgesia
Authors: Cordingley Timothy , Chepurin Daniel , Younis Ghada , Nassar Islam , Mitchell David 
Published: November 2021

Fast track arthroplasty is a holistic approach to patients who undergo total hip and knee arthroplasty, a journey or care that begins with setting patient’s expectation, optimising medical status, using intraoperative local anaesthetic infiltra-tion, decreasing narcotics usage either in spinal or post-operative medication, discouraging usage of patient controlled analgesia or urinary catheters, encouraging day of operation mobilisation and optimising post-operative physiotherapy protocols. The use of local infiltration analgesia (LIA) is a good alternative compared to other traditional pain management techniques. The purpose of adoption of LIA technique is to provide comfort from the trauma associated with hip and knee arthroplasty particularly for the first 36 h post-operatively, during the time of high post-operative pain, to facilitate increased post-operative mobilisation and function. LIA is safe and effective to achieve good outcomes, early mobilisation and decreasing length of stay without jeopardising clinical outcomes. This chapter discusses LIA and its multimodal approach to analgesia, regional anaesthesia and early mobilisation that improves overall patient experience and satisfaction. The chapter discusses LIA techniques, wound catheter placement, and postoperative protocol to achieve fast track hip and knee arthroplasty.
Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia
Authors: Subkorn Paweena , Norkaew Chosita , Deesrisak Kamolchanok , Tanyong Dalina 
Published: November 2021

Background
Punicalagin is the major phenolic compound found in pomegranate peels. It has several reported medical benefits, including antioxidant, anti-inflammatory, and anticancer properties. The present study investigated the anti-leukemic effects and the molecular mechanism of punicalagin on NB4 and MOLT-4 leukemic cell lines.

Methods
Leukemic cells were treated with punicalagin and cell viability was determined using MTS assay. Apoptosis and autophagy were analyzed by flow cytometry using Annexin V-FITC/PI and anti-LC3/FITC antibodies staining, respectively. Apoptotic and autophagic mRNA expression were determined using reverse transcription-quantitative PCR. STITCH bioinformatics tools were used to predict the interaction between punicalagin and its proposed target proteins.

Results
Results indicated that punicalagin decreased NB4 and MOLT-4 cell viability in a dose-dependent manner. Punicalagin, in combination with daunorubicin, exhibited synergistic cytotoxic effects. Punicalagin induced apoptosis through the upregulation of caspase-3/-8/-9, Bax and the downregulation of Bcl-2 expression. Punicalagin also promoted autophagy via the downregulation of mTOR and the upregulation of ULK1 expression. Cyclooxygenase-2 and toll-like receptor 4 were found to be involved in punicalagin-induced cell death in punicalagin-targeted protein interactions.

Conclusions
These results suggest that punicalagin exerts cytotoxic activities by suppressing proliferation and promoting apoptosis and autophagy by activating the caspase cascade, altering Bax and Bcl-2, and regulating autophagy via mTOR/ULK1 signaling.
Comparative Study of the Antimicrobial Efficacy of Three Medicinal Plants against Dermatophytic Pathogens
Authors: Folorunso Temitayo Veronica , Onifade Anthony Kayode , Oladunmoye Kolawole , Akinyele Bamidele Juliet 
Published: November 2021

Bixa orellana, Jatropha curcas and Cassia alata are three of the prominent plants used for traditional medicine in Nigeria. Dermatophytosis also known as tinea or ringworm is the most frequent superficial fungal infections in Nigeria.
Objective: In this Present Study, We Aimed at Comparing The Phytochemical Components and the Antifungal Efficacy of these Medicinal against Selected Dermatophytes.
Study Design: Cross Sectional Study among a Particular Population.
Place and Duration of Study: Department of Microbiology, Federal University of Technology, Akure, Ondo State. Between March 2019 and September 2019.
Methods: The phytochemical contents of the plants were determined and the in-vitro antifungal activities of Bixa orellana, Jatropha curcas and Cassia alata were screened against seven species of Trichophyton (T. ajelloi, T. mentagrophytes, T. rubrum, M.gypseum T. soudenensis, T. tonsurans and T. verrucosum) using agar dilution method.
Results: The phytochemical screening revealed the presence of flavonoid, saponin, phenol, steroids, glycoside, phytosteroids, alkaloids, terpenoid, tannin, and cardiac glycoside in various quantities. The findings from our study showed that the ethanol extracts of these medicinal plants have more antifungal activities than other solvents. However, the hexane and ethanol extracts of Jatropha curcas was observed to be significantly higher than other extracts. The zone of inhibition recorded ranges from 22 mm-32 mm and the minimum inhibitory concentration (MIC) of 12.5 mg/ml was recorded.
Conclusion: The ethanolic extract of Jatropha curcas showed broad effectiveness against the tested pathogens when compared to other plants and we conclude that the plants antifungal property is concentration dependent. However, we recommend further studies on these plants extracts using a large number of different isolates and solvents.
Atomically Dispersed Zinc(I) Active Sites to Accelerate Nitrogen Reduction Kinetics for Ammonia Electrosynthesis
Authors: Kong Yan , Li Yan , Sang Xiahan , Yang Bin , Li Zhongjian , Zheng Sixing , Zhang Qinghua , Yao Siyu , Yang Xiaoxuan , Lei Lecheng , Zhou Shaodong , Wu Gang , Hou Yang 
Published: November 2021

AbstractDeveloping highly active and stable nitrogen reduction reaction (NRR) catalysts for NH3 electrosynthesis remains challenging. Herein, an unusual NRR electrocatalyst is reported with a single Zn(I) site supported on hollow porous N‐doped carbon nanofibers (Zn1N–C). The Zn1N–C nanofibers exhibit an outstanding NRR activity with a high NH3 yield rate of ≈16.1 µg NH3 h−1 mgcat−1 at −0.3 V and Faradaic efficiency (FE) of 11.8% in alkaline media, surpassing other previously reported carbon‐based NRR electrocatalysts with transition metals atomically dispersed and nitrogen coordinated (TM‐Nx) sites. 15N2 isotope labeling experiments confirm that the feeding nitrogen gas is the only nitrogen source in the production of NH3. Structural characterization reveals that atomically dispersed Zn(I) sites with Zn–N4 moieties are likely the active sites, and the nearby graphitic N site synergistically facilitates the NRR process. In situ attenuated total reflectance‐Fourier transform infrared measurement and theoretical calculation elucidate that the formation of initial *NNH intermediate is the rate‐limiting step during the NH3 production. The graphitic N atoms adjacent to the tetracoordinate Zn–N4 moieties could significantly lower the energy barrier for this step to accelerate hydrogenation kinetics duing the NRR.
Antiangiogenic Nanomicelles for the Topical Delivery of Aflibercept to Treat Retinal Neovascular Disease
Authors: Zhao Xinxin , Seah Ivan , Xue Kun , Wong Wendy , Tan Queenie Shu Woon , Ma Xiaoxiao , Lin Qianyu , Lim Jason Y. C. , Liu Zengping , Parikh Bhav Harshad , Mehta Karishma N. , Lai Joel Weijia , Yang Binxia , Tran Kim Chi , Barathi Veluchamy Amutha , Cheong Kang Hao , Hunziker Walter , Su Xinyi , Loh Xian Jun 
Published: November 2021

AbstractThe traditional intravitreal injection delivery of antivascular endothelial growth factor (anti‐VEGF) to the posterior segment of the eye for treatment of retinal diseases is invasive and associated with sight‐threatening complications. To avoid such complications, there has been significant interest in developing polymers for topical drug delivery to the retina. This study reports a nanomicelle drug delivery system made of a copolymer EPC (nEPCs), which is capable of delivering aflibercept to the posterior segment topically through corneal–scleral routes. EPC is composed of poly(ethylene glycol) (PEG), poly(propylene glycol) (PPG), and polycaprolactone (PCL) segments. In this study, aflibercept‐loaded nEPCs (nEPCs + A) are capable of penetrating the cornea in ex vivo porcine eye models and deliver a clinically significant amount of aflibercept to the retina in laser‐induced choroidal neovascularization (CNV) murine models, causing CNV regression. nEPCs + A also demonstrate biocompatibility in vitro and in vivo. Interestingly, this study also suggests that nEPCs have intrinsic antiangiogenic properties. The ability to deliver anti‐VEGF drugs and the intrinsic antiangiogenic properties of nEPCs may result in synergistic effects, which can be harnessed for effective therapeutics. nEPCs may be a promising topical anti‐VEGF delivery platform for the treatment of retinal diseases.
Detection of Sub‐Terahertz Raman Response and Nonlinear Optical Effects for Luminescent Yb(III) Complexes
Authors: Kumar Kunal , Stefanczyk Olaf , Nakabayashi Koji , Imoto Kenta , Oki Yurie , Ohkoshi Shin‐ichi 
Published: November 2021

AbstractThe development of multifunctional oriented polar crystals combining diverse optical, nonlinear optical, and magnetic phenomena are desirable. Two enantiomorphic assemblies [YbIII(TPPO)3(NCE)3] (E = S (“YbS”), Se (“YbSe”); TPPO = triphenylphosphine oxide) are prepared. Both crystallites show ultralow‐frequency (ULF) Raman scattering for molecular materials with a value of 16 cm−1 (0.48 THz), originating from collective vibrations of the TPPO ligand and pseudohalides, which is supported by ab initio calculations. Moreover, YbS and YbSe crystals exhibit high‐intense second harmonic generation (SHG) phenomena along the threefold rotation c‐axis. The polarization‐variation of the pumping laser electric field experiment performed on single crystals gives a unique insight into the tensor elements constituting the R3 space group. Replacement of thiocyanide with selenocyanide in YbSe compound increases the second harmonic signal attributed to increased polarization. Besides, they also exhibit 4f‐metal centered high‐performance near‐infrared luminescence thermometric properties and weak single‐molecule magnet behaviors. They can also serve as a platform to study the magnetic and linear/nonlinear optical cross effects.