bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gradient‐based recursive parameter estimation for a periodically nonuniformly sampled‐data Hammerstein–Wiener system based on the key‐term separation
Authors: Liu Qilin , Ding Feng 
Published: July 2021

SummaryThe identification of the Hammerstein–Wiener (H‐W) systems based on the nonuniform input–output dataset remains a challenging problem. This article studies the identification problem of a periodically nonuniformly sampled‐data H‐W system. In addition, the product terms of the parameters in the H‐W system are inevitable. In order to solve the problem, the key‐term separation is applied and two algorithms are proposed. One is the key‐term‐based forgetting factor stochastic gradient (KT‐FFSG) algorithm based on the gradient search. The other is the key‐term‐based hierarchical forgetting factor stochastic gradient (KT‐HFFSG) algorithm. Compared with the KT‐FFSG algorithm, the KT‐HFFSG algorithm gives more accurate estimates. The simulation results indicate that the proposed algorithms are effective.
Two‐strategy evolutionary games with stochastic adaptive control
Authors: Liang Haili , Cui Ying , Zhou Zhao , Ding Baogang 
Published: July 2021

SummaryWe investigate the stochastic stability of replicator dynamics for evolutionary games with multiplicative noises and time delay in this article. We study evolutionary games in infinite well‐mixed populations, among which each individual has two strategies, to cooperate or defect, each time when it is matched up with other individuals to play the two‐strategy game together. This article is concerned with the extension of the well‐known two‐strategy evolutionary games to the stochastic case with adaptive control. We analyze the stochastic replicator dynamics with time delays and provide conservative bounds on the strength of noise and the time delay for the almost sure exponential stability of stochastic systems. Finally, numerical simulations based on triple classical game models (snowdrift game, hunt stag game, and prisoner's dilemma game) are given to illustrate the preceding theoretical results.
Synergistical Starvation and Chemo‐Dynamic Therapy for Combating Multidrug‐Resistant Bacteria and Accelerating Diabetic Wound Healing
Authors: Li Danxia , Chen Tao , Zhang Yanfang , Xu Yuanhong , Niu Haitao 
Published: July 2021

AbstractThe application of the antibiotic drug has dramatically decreased the infection and promoted the development of surgery, but drug‐resistant bacteria appeared along with the abuse of antibiotics. Especially, wound in diabetic patients provides more glucose for bacteria resulting in poor wound healing. Therefore, it is imminent to explore advanced agents for combating multidrug‐resistant bacteria and accelerating diabetic wound healing. Herein, metal–organic frameworks based nanoreactors loaded with glucose oxidase (GOx) and peroxidase‐like bovine hemoglobin (BHb) are designed to construct an effective cascaded catalytic antibacterial system. Therein, GOx can cost the glucose, and release H2O2 simultaneously, which can then be transformed into hydroxyl radicals by BHb. As a result, the as‐prepared nanoreactors can play the roles of both starving and killing toward the multidrug‐resistant bacteria. Furthermore, the produced gluconic acid can reduce the pH of working condition, which is beneficial for both the enhancement of peroxidase activity and the inhibition of the bacteria growth. More importantly, the constructed nanoreactors can be degraded and excreted from the body in the form of feces, which render the as‐proposed nanoreactors qualified as effective and safe materials for both combating multidrug‐resistant bacteria in vitro and accelerating the diabetic wound healing in vivo of the mouse model.
A Straightforward Approach for High‐Level Anticounterfeiting and Antibacterial Applications Based on Photoluminescent Fibers/Yarns
Authors: Lyu Pei , Li Guoqing , Zhao Yuting , Chi Hao , Wang Xungai , Hurren Christopher , Chen Dongzhi , Xu Weilin , Liu Xin 
Published: July 2021

AbstractRecently, emergent luminescent fibers have attracted extensive attention due to their intriguing applications. However, developments of the luminescent fibers are severely limited by their high‐cost and low efficient manufacturing protocols including in situ growth, dry‐wet spinning, co‐electrospinning, and multistep dip‐coating. Herein, a cost‐efficient and large‐scalable approach (namely, one‐step dip‐coating) is proposed. In this work, the photoluminescent fibers/yarns are fabricated by one‐step dipping of pristine fibers/yarns in dispersions of hybrid dots (silicon/carbon). Subsequently, Janus fabrics with striking photoluminescent patterns are developed by weaving, knitting, and braiding, respectively. An innovative anticounterfeiting technique is further developed by combing the merits of the photoluminescent fibers/yarns with textile weaving methods. The designed photoluminescent patterns can endow the weaving fabrics with excellent concealment performance. As far as it is well known, it is the first time to achieve asymmetric photoluminescent patterns on two sides of the woven fabrics by this innovative technology. Additionally, the fabrics treated with hybrid dots exhibit excellent antibacterial ability against both Staphylococcus aureus and Escherichia coli. These findings can not only provide an unprecedented insight for realizing high‐level anticounterfeiting applications, but also guide to exploit versatile applications in medical care, fashion design, stage performances, trademark, and confidential documents in the future.
Atomic Imaging of Electrically Switchable Striped Domains in β′‐In2Se3
Authors: Chen Zhi , Fu Wei , Wang Lin , Yu Wei , Li Haohan , Tan Clement Kok Yong , Abdelwahab Ibrahim , Shao Yan , Su Chenliang , Sun Mingzi , Huang Bolong , Loh Kian Ping 
Published: July 2021

Abstract2D ferroelectricity in van‐der‐Waals‐stacked materials such as indium selenide (In2Se3) has attracted interests because the ferroelectricity is robust even in ultrathin layers, which is useful for the miniaturization of ferroelectric field effect transistors. To implement In2Se3 in nanoscale ferroelectric devices, an understanding of the domain structure and switching dynamics in the 2D limit is essential. In this study, a biased scanning tunnelling microscopy (STM) tip is used to locally switch polarized domains in β′‐In2Se3, and the reconfiguration of these domains are directly visualized using STM. The room‐temperature surface of β′‐In2Se3 breaks into 1D nanostriped domains, which changes into a zig‐zag striped domains of β″ phase at low temperatures. These two types of domains can coexist, and by applying a tip‐sample bias, they can be interchangeably switched locally, showing volatile or nonvolatile like behavior depending on the threshold voltage applied. An atomic model is proposed to explain the switching mechanism based on tip‐induced flexoelectric effect and the ferroelastic switching between β′ and β″ phases.
Replicability of leptin associations with testosterone, estradiol, follicle‐stimulating hormone, and luteinizing hormone in healthy Ache men of Paraguay: A multiple daily assessment
Authors: Harries Victoria , Bribiescas Richard G. 
Published: July 2021

AbstractObjectiveAssociations between leptin and male reproductive hormone levels have been reported in men. However, few of these investigations have focused on associations in healthy men without obesity or overweight or nonindustrial societies.MethodsWe test hypotheses that leptin is associated with testosterone, estradiol, luteinizing hormone (LH), and follicle‐stimulating hormone (FSH) within healthy Ache men, an indigenous nonindustrialized South American community using archived data.ResultsArchived data of serum FSH, LH, leptin, and salivary testosterone and estradiol levels collected from healthy Ache men (n = 17, mean age = 37.1 ± 14.2) on two separate days revealed leptin was correlated with FSH (D1 p = .07, D2 p = .009) and PM testosterone (TsalPM, D1 p = .05, D2 p = .05). However, controlling for age, associations with FSH were not significant. Mean comparisons and linear regression of values over 2 days resulted in leptin (t = 0.08, p = .94, r2 = .58, p = .0009), LH (t = 1.16, p = .26, r2 = .11, p = .27), FSH (U = 131.5, p = .88, r2 = .63, p = .0002), AM testosterone (TsalAM, t = 4.0, p = .001, r2 = .02, p = 0.75), and TsalPM (t = 2.99, p = .01, r2 = .56, p = .01).ConclusionWe conclude (a) FSH, TsalPM, and leptin levels within individual men are relatively invariant over a span of days; (b) despite small sample sizes, results suggest ecological and lifestyle variation can contribute to variation in leptin associations with male reproductive hormones.
An overview of microwave assisted cyanation reactions
Authors: Fairoosa Jaleel , Shamna Salahudeen , Neetha Mohan , Anilkumar Gopinathan 
Published: July 2021

AbstractCyano compounds are versatile intermediates in organic synthesis and have immense applications in diverse sectors including pharmaceuticals, industries, and agrochemicals. Microwave heating has enlightened synthetic chemistry due to its eco‐friendly nature ever since the first report. High product yield, shorter reaction time, less byproduct formation, selectivity, reproducibility and high product purity made this heating technique more acceptable. This review focuses on the diverse aspects of microwave assisted cyanation reactions. This is the first review on this topic and covers literature from 2000 to 2020.
An efficient nanoscale representative volume element simulation including graded interphase for tensile behavior of epoxy/silica nanocomposites
Authors: Zamanian Milad , Ashenai Ghasemi Faramarz , Mortezaei Mehrzad 
Published: July 2021

AbstractThe behavior of interphase‐particle adhesion and interphase region around the nanoparticles can significantly affect the stress distribution and mechanical properties of polymeric nanocomposites. In this study, the elastic modulus of epoxy/silica nanocomposites is analyzed using the finite element method and different mathematical models. A nanoscale representative volume element including graded interphase, homogenous interphase, and no interphase model is implemented. Furthermore, the effect of interfacial adhesion is also considered. The final elastic modulus was clearly affected by the interphase modulus, especially at higher nanoparticle content. Under imperfect interfacial bonding, the existence of an interphase region leads to a slight increase in modulus, and in the absence of that area, the elastic modulus decreases to 3.28 GPa. In perfect bonding models, stress transferred from the matrix to interphase and, then, to nanoparticle, which led to a significant increase in elastic modulus. Unlike the imperfect bonding, the maximum stress was located in the elements along to the loading direction. A maximum 26% increase in elastic modulus for perfect bonding/graded interphase model with 6.54 vol% of nanosilica particles compared to bulk epoxy was achieved. Finally, on comparing the FEM analysis and theoretical results with the experimental data, good agreement between obtained results was found.
Humoral and Cellular Immune Responses to SARS–CoV‐2 Infection and Vaccination in Autoimmune Disease Patients With B Cell Depletion
Authors: Simon David , Tascilar Koray , Schmidt Katja , Manger Bernhard , Weckwerth Leonie , Sokolova Maria , Bucci Laura , Fagni Filippo , Manger Karin , Schuch Florian , Ronneberger Monika , Hueber Axel , Steffen Ulrike , Mielenz Dirk , Herrmann Martin , Harrer Thomas , Kleyer Arnd , Krönke Gerhard , Schett Georg 
Published: July 2021

ObjectiveB cell depletion is an established therapeutic principle in a wide range of autoimmune diseases. However, B cells are also critical for inducing protective immunity after infection and vaccination. We undertook this study to assess humoral and cellular immune responses after infection with or vaccination against SARS–CoV‐2 in patients with B cell depletion and controls who are B cell–competent.MethodsAntibody responses (tested using enzyme‐linked immunosorbent assay) and T cell responses (tested using interferon‐γ enzyme‐linked immunospot assay) against the SARS–CoV‐2 spike S1 and nucleocapsid proteins were assessed in a limited number of previously infected (n = 6) and vaccinated (n = 8) autoimmune disease patients with B cell depletion, as well as previously infected (n = 30) and vaccinated (n = 30) healthy controls.ResultsAs expected, B cell and T cell responses to the nucleocapsid protein were observed only after infection, while respective responses to SARS–CoV‐2 spike S1 were found after both infection and vaccination. A SARS–CoV‐2 antibody response was observed in all vaccinated controls (30 of 30 [100%]) but in none of the vaccinated patients with B cell depletion (0 of 8). In contrast, after SARS–CoV‐2 infection, both the patients with B cell depletion (spike S1, 5 of 6 [83%]; nucleocapsid, 3 of 6 [50%]) and healthy controls (spike S1, 28 of 30 [93%]; nucleocapsid, 28 of 30 [93%]) developed antibodies. T cell responses against the spike S1 and nucleocapsid proteins were found in both infected and vaccinated patients with B cell depletion and in the controls.ConclusionThese data show that B cell depletion completely blocks humoral but not T cell SARS–CoV‐2 vaccination response. Furthermore, limited humoral immune responses are found after SARS–CoV‐2 infection in patients with B cell depletion.
Contribution of rationality to vaccine attitudes: Testing two hypotheses
Authors: Tomljenovic Helena , Bubic Andreja , Erceg Nikola 
Published: July 2021

AbstractAlthough previous studies have demonstrated an association between vaccine attitudes and cognitive biases, often resulting in vaccination hesitancy, the exact contribution of rationality has not been fully clarified. We tested two hypotheses regarding the impact of rationality on vaccine attitudes stemming from bounded and expressive rationality. We focused on parental vaccine attitudes operationalized by the affective, behavioral, and cognitive attitude components and investigated how these are influenced by disillusionment toward authorities and ability to engage in rational thinking operationalized using cognitive reflection and heuristics and biases tasks. The study was of a cross‐sectional correlational design with a non‐probabilistic sample of 823 volunteer participants surveyed online in April and May 2018 in Croatia. The results identified disillusionment toward authorities as a predictor of all components. Furthermore, performance on heuristics and biases tasks also predicted the affective and cognitive, but not the behavioral component, whereas cognitive reflection had no impact on vaccine attitudes. Next, a moderation effect of disillusionment toward authorities on the association between the omission bias task and all attitude components was identified. Parents with low disillusionment demonstrated positive vaccine attitudes regardless of their rationality, whereas for parents with high disillusionment a significant positive correlation between performance on the omission bias task as assessed with a vaccination vignette and attitudes was identified. This suggests that the ability to resist vaccine specific omission bias, that is, higher rationality, can decrease the negative effects of disillusionment, which supports the bounded rationality hypothesis.
Rapid self‐assembly of γPNA nanofibers at constant temperature
Authors: Kumar Sriram , Dhami Isha , Thadke Shivaji A. , Ly Danith H. , Taylor Rebecca E. 
Published: July 2021

AbstractPeptide nucleic acids (PNAs) have primarily been used to achieve therapeutic gene modulation through antisense strategies since their design in the 1990s. However, the application of PNAs as a functional nanomaterial has been more recent. We recently reported that γ‐modified peptide nucleic acids (γPNAs) could be used to enable formation of complex, self‐assembling nanofibers in select polar aprotic organic solvent mixtures. Here we demonstrate that distinct γPNA strands, each with a high density of γ‐modifications can form complex nanostructures at constant temperatures within 30 minutes. Additionally, we demonstrate DNA‐assisted isothermal growth of γPNA nanofibers, thereby overcoming a key hurdle for future scale‐up of applications related to nanofiber growth and micropatterning.
An engineered cellobiohydrolase I for sustainable degradation of lignocellulosic biomass
Authors: Pramanik Subrata , Semenova Margarita V. , M. Rozhkova Aleksandra , Zorov Ivan N. , Korotkova Olga , Sinitsyn Arkady P. , Davari Mehdi D. 
Published: July 2021

AbstractThis study provides computational‐assisted engineering of the cellobiohydrolase I (CBH‐I) from Penicillium verruculosum with simultaneous enhanced thermostability and tolerance in ionic liquids, deep eutectic solvent, and concentrated seawater without affecting its wild‐type activity. Engineered triple variant CBH‐I R1 (A65R‐G415R‐S181F) showed 2.48‐fold higher thermostability in terms of relative activity at 65°C after 1 h of incubation when compared with CBH‐I wild type. CBH‐I R1 exhibited 1.87‐fold, 1.36‐fold, and 1.57‐fold higher specific activities compared with CBH‐I wild type in [Bmim]Cl (50 g/L), [Ch]Cl (50 g/L), and two‐fold concentrated seawater, respectively. In the multicellulases mixture, CBH‐I R1 showed higher hydrolytic efficiency to hydrolyze aspen wood compared with CBH‐I wild type in the buffer, [Bmim]Cl (50 g/L), and two‐fold concentrated seawater, respectively. Structural analysis revealed a molecular basis for the higher stability of the CBH‐I structure in which A65R and G415R substitutions form salt bridges (D64 … R65, E411 … R415) and S181F forms π–π interaction (Y155 … F181), leading to stabilize surface‐exposed flexible α‐helixes and loop in the multidomain β‐jelly roll fold structure, respectively. In conclusion, the variant CBH‐I R1 could enable efficient lignocellulosic biomass degradation as a cost‐effective alternative for the sustainable production of biofuels and value‐added chemicals.
Connecting strategic orientation, innovation strategy, and corporate sustainability: A model for sustainable development through stakeholder engagement
Authors: van Lieshout Johannes W. F. C. , Nijhof Andre H. J. , Naarding Gijs J. W. , Blomme Robert J. 
Published: July 2021

AbstractThis paper aims to enhance our understanding of the relationship between organizations' strategic orientation (i.e., instrumental, equidistant, and stewardship) and their innovational strategy (i.e., organizational ambidexterity and open innovation), and this relationship's influence on their sustainability performance. We expected organizations' strategic orientation to influence their innovational strategy and exhibit better corporate sustainability. We focused on 12 different multinational organizations in the Eurozone and found that inbound open innovation acts as a driver for corporate sustainability while simultaneously positively enabling organizations to pursue both financial and social initiatives. After suggesting open innovation as a new corporate sustainability antecedent, we only found empirical evidence of inbound open innovation. However, we would suggest that if organizations incorporated outbound open innovation in their strategy, they could likely improve their corporate sustainability. Also, we found that achieving an equidistant or stewardship orientation paves the way for sustainability to become an integral part of an organization's innovational culture and actualizes the organization's strategic behavior. Our findings further contribute to a deeper understanding of organizations' characteristics as their sustainability commitment grows and as they move from an instrumental to a stewardship orientation and implement an open innovational strategy.
A Fixed Reconstruction of Partially Edentulous Patient With Systemic Scleroderma: A 4.8‐year Follow‐Up Case Report
Authors: Bayram Yeter Eylul , Eskan Mehmet Akif 
Published: July 2021

IntroductionSystemic scleroderma (SSc) is a progressive autoimmune multisystem disease affecting several organs. In the oral cavity, its manifestations include enlarged periodontal ligament, xerostomia, microsomia, alveolar bone loss, and premature teeth loss. A removable prosthesis would not be a treatment option due to loss of hand dexterity, reduced chewing capacity, microsomia, and xerostomia in these patients. Alternatively, implant‐supported fixed restorations are a plausible treatment for these patients. However, there is very limited literature showing implant survival rate in patients with SSc for a long follow‐up.Case PresentationA 57‐year‐old female patient with SSc presented to our clinic. She was diagnosed with SSc 25 years ago. Initial clinical and radiological examination revealed that she showed slight to moderate chronic periodontitis, tooth cavities, remaining tooth tips, and a partial edentulism in the posterior areas. A total of seven implants were placed at different time points. The remaining upper teeth were crowned. At 4.8 years follow‐up, the placed implants showed no sign of peri‐implant disease.ConclusionThis case report indicated that 4.8 years of follow‐up revealed good oral hygiene and clinically or radiologically no sign of peri‐implant disease around the implants in a patient with SSc. Implant‐supported fixed restoration could be a viable treatment approach in these patients.
A “fully upper extremity” bailout of direct transaxillary large bore arterial access: A refinement within arm's reach?
Authors: Mathur Moses , Zack Chad J. , Heatley Ashley , Rhodes Denise , Yamane Kentaro , Gilchrist Ian C. , Kozak Mark 
Published: July 2021

AbstractContemporary direct (“fully percutaneous”) transaxillary (TAx) large‐bore arterial access technique advocates for a 0.018” wire to be passed from femoral arterial access to axillary artery to serve percutaneous bailout options. However, in certain patients, avoiding femoral arterial access entirely may be desired. We describe the merits of a “fully upper extremity” (FUE) bailout approach, as a refinement to previously described direct TAx technique.
Forecasting hydropower generation byGFDL‐CM3climate model and hybrid hydrological‐Elman neural network model based on Improved Sparrow Search Algorithm (ISSA)
Authors: Wang Haizhen , Wu Xuerui , Gholinia Fatemeh 
Published: July 2021

AbstractOne of the most sensitive factors affecting hydropower generation is climate change. The objective of this study is to forecast the hydropower generation under the influence of climate change for the next 50 years. For this purpose, the GFDL‐CM3 model is used under three scenarios: RCP2.6, RCP4.5, and RCP8.5 to predict precipitation and temperature. Any change in the inlet flow to the turbine will cause changes in the hydropower output. Therefore, the more accurately the flow is estimated, the hydropower generation is forecasted more accurately. In this research, a hydrological‐neural network hybrid model for flow prediction is presented in which the Improved Sparrow Search Algorithm (ISSA) has been used. The results forecasting climate parameters showed that the average annual rainfall, runoff, and evaporation have a downward trend compared to the control period. The minimum and maximum annual temperatures have an increasing trend compared to the control period. To evaluate the hydropower generation Aras dam, the HEC‐Ressim reservoir model is utilized. By comparing the average annual hydropower with the control period, it is known that the power generation will decrease in future years. The average annual electricity generated by hydropower under the scenario RCP2.6 and RCP4.5 and RCP8.5 in the next 50 years will decrease by approximately 3.36, 4.62, and 6.64 MW.