bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design and Execution of Drilling and Blasting Works Using Modern Scanning Techniques
Authors: Gheorghiosu Edward , Becuţ Silviu 
Published: December 2024

Abstract
The basic principles for the design of the parameters of the shooting techniques are: the exact definition of the technical and economic objectives and especially those related to the granulometry of the demolished material, knowledge of the characteristics of the rock massif (degree of cracking and local fracturing, compressive and tensile strength of the rocks, the degree of homogeneity and their compactness), knowing in detail the possibility of executing the firing holes for loading and crushing the demolished material, knowing the explosive used and its behavior in the concrete conditions of the quarry, specifying the restrictions imposed by the protection of the environment (distances from the surrounding objectives, the maximum accepted levels of vibrations, noises, dust). In order for all these principles to be fulfilled, there are methods of designing and executing the drilling and shooting works so that the results of the shooting works are those expected in conjunction with a rational exploitation in safe conditions. The paper presents a case study where the design and execution of drilling and blasting parameters was successfully applied using modern equipment.
Living Lab – A Systemic Innovation Approach to Restoring Soil Health on Unproductive Land in the Jiu Valley
Authors: Dunca Emilia-Cornelia , Radu Sorin-Mihai , Irimie Sabin , Varga Lucia-Ana , Panaite Fabian 
Published: December 2024

Abstract
The Living Lab is an innovative and effective approach to restoring soil health on unproductive land. Through collaboration between different researchers and the use of adaptable and sustainable solutions, this method can transform degraded land into valuable resources, contributing to agricultural sustainability and the development of local communities. The establishment of a Living Lab on the non-productive lands of Jiu Valley as a systemic approach to innovation in which all interested parties are involved in the research and application of solutions to restore soil health is a challenge. The paper presents the methods used, the working hypotheses, the data analysis and the interpretation of the results obtained in the living lab created to study the cultivation of biomass, its energy utilization and the obtaining of biofertilizers. Multiple approaches regarding the obtained biofertilizers and their application to restore soil health are presented. The limits and conclusions of the innovative research carried out so far in the Living Lab are presented.
Training Scenarios for Mine Rescuers Aimed at Selecting and Building Rescue Teams Able of Intervening in Major Incidents
Authors: Nicolescu Cristian , Găman George Artur , Pupăzan Daniel , Ilie Cosmin 
Published: December 2024

Abstract
In mining rescue operations, the practical training of rescue personnel plays an essential role in the selection and configuration of rescue teams that intervene in critical situations, major incidents, accidents or other events occurring in underground mining works. Practical training can be conducted through monthly scheduled practical exercises at rescue stations within a mining unit, as well as through modern training means available at INCD-INSEMEX Petroșani (virtual reality, mobile training facility for rescuers) used in the process of instruction and re-instruction of mining rescuers. Mining rescuers’ training level can be quantified through both physical and mental training by their reactions in certain critical situations, which can be created using virtual reality. Furthermore, the monitoring of the rescuers’ physiological parameters before, during and after performing the practical exercise is also of particular importance. This monitoring can be carried out through the equipment available in the mobile training facility. The current paper aims to establish complex training scenarios for mining rescuers to select and configure rescue teams that can act in case of explosions, mine fires or other events.
Morphological Ways of Creating Eponyms in English Medical Terminology
Authors: Stehnitska Liubov , Teleky Mariia 
Published: December 2024

Abstract
In English medical terminology, there is a steady tendency for the functioning and even an increase in the number of eponymous terms. The authors focus on the term formation potential of eponyms, ways of their creation, and the semantics of derived units. This paper highlights the main morphological methods of creating eponymous terms in English medical terminology. The suffixation is represented by the suffixes: -ia, -(i)an, -ean, -ella, -(i)al, -ic, -osis, -iasis, -ism, -itis, -oma, -ize. The productivity of this method is provided by derivational suffixes with a semantic burden borrowed from Greek and Latin languages. The semantic range of suffixes contributes to creating new terms with similar meanings. Prefixation in eponymous terms was limited to using prefixes pre- and non-. Only two terms were identified in our investigation: pre-Alzheimer’s brain and non-Hodgkin’s lymphoma. The majority of eponymous terminological units are found to be formed by affix combination. The components of this type of eponymous term are the prefixes a-, anti-, de-, hemi-, non-, post-, pre-, and the suffixes -ian, -ic, -ism,-ize such as anti-Mullerian hormone or hemiparkinsonism. The prefix performs a word-building role as an affix with a mutational meaning, while the suffix generalizes and specifies the meaning of the term. The methods of the word and stem composition are not prevailing. There are structural models with the morphemes pseudo- in the preposition and -like in the postposition: pseudo-Cushing syndrome and Burkitt-like lymphoma. Morphological methods of creating eponymous terms combine borrowed and native English morphemes where the elucidation of derivatives relies on the meanings of their components. Suffixation occupies a dominant position in the creation of eponymous terminological units.
Zelda Fitzgerald in Love and Madness: Her Letters to F. Scott
Authors: Tucan Gabriela 
Published: December 2024

Abstract
The article examines Zelda Fitzgerald’s mental health struggles during the 1930s through her letters to F. Scott Fitzgerald. It highlights her resistance to psychiatric treatment and marital and societal constraints, highlighting her creative letter writing and art as tools for agency and autonomy. Despite prolonged institutionalisation and personal challenges, Zelda’s letters reveal her struggle for personal and professional identity, contrasting poetic self-expression with the clinical detachment and sterility of psychiatric discourse.
A Postmodernist Rewriting Of Homer’s Penelope: Margaret Atwood’s The Penelopiad
Authors: Petruş Raluca-Andreea 
Published: December 2024

Abstract
The article analyses Margaret Atwood’s reinterpretation of the Ithacan queen, Penelope, the wife of Odysseus, taking into consideration the silence-voice interplay between the original female character and her postmodernist re-representation, Penelope 2.0, the protagonist of The Penelopiad. In the Canadian writer’s novel, Penelope’s voice gets empowered through narrative means. Her voice reaches its peak or highest degree of expression in Atwood’s The Penelopiad, namely due to its main character and narrator, Penelope 2.0. Considering that a female first-person narrator elaborates the novel’s narrative, the article demonstrates how Penelope 2.0 expresses her feelings and thoughts regarding a series of events which occurred in the original text of The Odyssey, events which she elucidates by offering direct, well-developed insight, without any constraints.
Both Critic and Not: A Case Study of David Foster Wallace’s Literary Reviews and Essays
Authors: Săran Raul 
Published: December 2024

Abstract
While often described as a significant part of David Foster Wallace’s contribution to American culture, his essays highlight some of the author’s principles and values when it comes to American fiction, entertainment and the general status quo of American society in the 1990s and 2000s. There are several essays where Wallace discusses literary works, from Franz Kafka and Zbigniew Herbert to John Updike and Cormac McCarthy, as well as essays based on the evolution of American fiction at the turn of the millennium. Based on a selected corpus of essays from three of his essay collections – A Supposedly Fun Thing I’ll Never Do Again, Consider the Lobster and Both Flesh and Not – the purpose of the paper is to highlight and discuss the ways in which Wallace analyses and understands literature not just as a writer, but also as an essayist and reviewer.
Peran Rasa Kesepian dan Harapan dalam Memprediksi Kecenderungan Depresi pada Mahasiswa
Authors: Hidayati Hidayati , Poerwandari Elizabeth Kristi 
Published: December 2024

Penelitian ini bertujuan untuk melihat model dari konstruk positif yaitu harapan (hope) dan konstruk negatif yaitu kesepian (loneliness) dalam memprediksi kecenderungan depresi pada mahasiswa. Kecenderungan depresi merupakan fenomena yang sangat sering dijumpai. Mahasiswa berada pada tahap transisi antara kehidupan remaja dan kehidupan dewasa. Kondisi ini cukup membingungkan dimana mereka mulai berusaha independen namun masih belum dapat independen seutuhnya. Tuntutan akademik, rendahnya kemampuan sosial, tinggal terpisah dari orang tua seringkali menyebabkan rasa kesepian. Sementara itu, adanya harapan yang dimiliki oleh individu membuat mereka lebih fleksibel dalam menghadapi kesulitan dan berusaha mencapai tujuan sehingga menjadi faktor protektif dari kondisi depresi. Partisipan penelitian ini sebanyak 410 mahasiswa aktif program sarjana yang berasal dari Jakarta, Bogor, Depok, Tangerang, dan Bekasi. Hasil analisa statistik dengan menggunakan regresi berganda menunjukkan bahwa model cocok dengan asumsi dimana kesepian memprediksi kehadiran depresi dan harapan berperan signifikan sebagai faktor pelindung dari munculnya depresi (R2=0,456; F(6,409) = 58,183; p<.05).
Utility of fine-needle aspiration cytology combined with flow cytometry in extramedullary hematolymphoid lesions – A cross-sectional study
Authors: Murugan Roobashri , Manivannan Prabhu , Gochhait Debasis , Kar Rakhee , Siddaraju Neelaiah , Sahadevan Sushya 
Published: December 2024

Objective:
Flow cytometry (FC) can be an adjunct to fine-needle aspiration cytology (FNAC) in the diagnosis and subclassification of hematolymphoid lesions. This study evaluates the utility of FC in diagnosing extramedullary hematolymphoid lesions in fine-needle aspirate samples.

Material and Methods:
This cross-sectional study enrolled patients who presented to the FNAC clinic and suspected to have hematolymphoid lesions (nodal and extra nodal lesions) from August 2020 to June 2022. Sixty-seven cases of hematolymphoid malignancies and 67 cases without hematolymphoid malignancies were included. The combined FNAC/FC diagnosis was compared with the gold standard: Biopsy, cell block, or peripheral blood/bone marrow aspirate FC.

Results:
Of 67 lymphoma cases, 63 were of the primary type and 4 were diagnosed with suspected recurrence/residual disease. Moreover, 57 cases were nodal, and 10 were extranodal. Four of the patients had discordant findings between FNAC and FC. The gold standard was available only in 56 cases, of which 5 had discordant findings between combined FNAC/FC and the gold standard. We subclassified 34 cases based on combined FNAC/FC. The five cases included anaplastic large cell lymphoma (1/5), classic Hodgkin lymphoma (3/5), and one case of atypical lymphoid hyperplasia. Non-contributory FC was attributed to the presence of large cells/necrosis/nodular lymphocyte predominant Hodgkin lymphoma/metastasis/Castleman disease/technical problem.

Conclusion:
Combining FC with FNAC enhances diagnostic accuracy and helps subclassify lymphoma. Future works should explore whether it can replace excision biopsy, especially in recurrent cases.
PR/SET domain 1 targeting glutathione peroxidase 4 regulates chronic hepatitis B liver fibrosis through ferroptosis
Authors: Wu Wenjun , Ke Wenhai , Shi Weiping , Lin Ting , Lin Shenglong , Lin Minghua , Ma Huaxi , Gao Haibing 
Published: December 2024

Objective:
Addressing the inhibition and reversal of chronic hepatitis B fibrosis is an urgent global challenge, which highlights the critical need to understand its underlying mechanisms. Inhibiting the activation of hepatic stellate cells (HSCs) is an important strategy for fibrosis reversal. In particular, the induction of ferroptosis in HSCs presents a promising avenue for curtailing liver fibrosis. Therefore, this study explores the influence of PR/SET domain 1 (PRDM1), which is a transcriptional regulator, on the progression of liver fibrosis by regulating HSC ferroptosis through glutathione peroxidase 4 (GPX4).

Material and Methods:
We used protein–protein interaction databases to analyze the interacting proteins of GPX4. The messenger ribonucleic acid levels of PRDM1 and GPX4 in liver tissues with varying degrees of fibrosis were examined using quantitative polymerase chain reaction. Cell lines with interference and overexpression of PRDM1/GPX4 were established. Reactive oxygen species (ROS) activity, malondialdehyde (MDA) concentration, cell proliferation capacity, as well as the expression levels of GPX4, a-smooth muscle actin, vimentin, and desmin, were assessed to investigate the relationship between PRDM1 and hepatic fibrosis, as well as its impact on ferroptosis in HSCs.

Results:
A significant negative correlation was observed between the transcriptional regulator PRDM1 and GPX4. As the degree of fibrosis worsened, PRDM1 decreased significantly, whereas GPX4 increased significantly. The overexpression of PRDM1 markedly increased ROS and MDA concentrations, but it decreased cell proliferation capacity, GPX4 expression levels, and activation marker protein levels. Interference with PRDM1 yielded opposite results. The expression level of GPX4 did not affect PRMD1 expression levels. Compared with cells with single interference of PRDM1, simultaneous interference with PRDM1 and GPX4 significantly inhibited the activity and proliferation capacity of HSCs. It also elevated ROS activity and MDA concentrations. When ferroptosis inhibitors were added, ROS activity and MDA concentrations decreased, and the proliferation capacity and activity of HSCs increased. Opposite results were obtained when PRDM1 and GPX4 were overexpressed simultaneously.

Conclusion:
PRDM1 is implicated in the occurrence and progression of hepatic fibrosis. It may act as an upstream regulatory factor of GPX4, which exerts control over ferroptosis by suppressing the transcription of GPX4. Ultimately, the activation of HSCs is promoted.
Geniposide alleviates post-myocardial infarction-induced pyroptosis by modulating the thioredoxin-interacting protein/NLRP3 signaling pathway
Authors: Jiang Youqin , Su Yao , Li Chen , Jiang Weiwei , Wei Yang , Chang Guanglei , Liu Ya , He Honghong 
Published: December 2024

Objective:
Geniposide (GP) provides myocardial cells with protection against pyroptosis-induced damage. However, the mechanisms governing GP’s effect on the thioredoxin-interacting protein (TXNIP)/nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) signaling pathway remain unclear. This study aimed to explore how GP alleviates post-myocardial infarction (MI)-induced pyroptosis through regulation of the TXNIP/NLRP3 pathway.

Material and Methods:
In vivo studies: MI models were established, mouse body weight, heart rate, and blood glucose levels were monitored, and methods, such as cardiac ultrasound, hematoxylin–eosin staining, triphenyltetrazolium chloride staining, terminal deoxynucleotidyl transferase 2'-deoxyuridine 5'-triphosphate nick end labeling staining, quantitative polymerase chain reaction (qPCR), and Western blot (WB), were used to explore the effect of GP on myocardial cell pyroptosis. We explored the role of NLRP3 in GP’s antimyocardial cell pyroptosis through qPCR, WB, immunofluorescence, enzyme-linked immunosorbent assay (ELISA), and other methods. In vitro studies: A chronic hypoxia (CH) cell model was established, and detection methods, such as cell counting kit-8 assay, transmission electron microscopy, ELISA, and immunological assays, were used to explore the effects of GP on CH myocardial cell pyroptosis and GP’s inhibition of the TXNIP/NLRP3 signaling pathway to resist CH myocardial cell pyroptosis.

Results:
In vivo studies revealed that after the treatment with GP, the infarct area of mice’s hearts significantly decreased, cardiac structure and function notably improved, fibroblast proliferation in cardiac tissues decreased significantly, and the pyroptosis level of myocardial cells decreased. GP treatment significantly downregulated the expression levels of type I collagen (Col I), Col III, TXNIP NLRP3, caspase-1, and gasdermin D N-terminal (GSDMD-N). The inhibition of NLRP3 also reduced the expressions of NLRP3, TXNIP, caspase-1, and GSDMD-N in the cardiac tissue, which is concomitant with a decline in reactive oxygen species (ROS) production. In addition, in vitro studies unveiled that GP effectively alleviated pyroptosis in CH myocardial cells, reducing pyroptosis rates, interleukin (IL)-1β, IL-18, lactate dehydrogenase, and creatine kinase-muscle/brain levels. This protective effect was achieved by inhibiting the TXNIP/NLRP3 signaling pathway.

Conclusion:
GP greatly diminishes the extent of infarcted myocardial tissue and mitigates pyroptosis, which improves cardiac structure and function through modulation of the TXNIP/NLRP3 pathway. Furthermore, the inhibition of NLRP3 lowers the expressions of factors associated with pyroptosis in the cardiac tissue and reduces ROS production.
Correlation of patient characteristics with peak enhancement time for pediatric cardiac computed tomography in congenital heart disease
Authors: Visakh T. , Priya P. S. , Panakkal Nitika C. , Banga Gunjan , Prakashini Koteshwar 
Published: December 2024

Objectives:
Cardiac computed tomography (CCT) plays a key role in diagnosing congenital heart disease (CHD), emphasizing the need for specialized protocols in newborns due to CHD’s complexity. The aim is to explore the relationship between peak enhancement time (PET) and various parameters during CHD assessment with CCT.

Material and Methods:
The study involved 38 CHD patients undergoing CCT, with observations made on their heart rate, respiratory rate, saturation, cardiac output, weight, height, and age. The PET for each case was determined, and Spearman’s rank correlation was employed to evaluate the association between these parameters and the PET.

Results:
The median PET was 20.63 s, with a mean aortic Hounsfield unit of 512.16 ± 160.56. A moderate negative correlation was found between PET and both heart rates (r = −0.42, P = 0.009) and respiratory rates (r = −0.41, P = 0.01), whereas a negligible positive correlation (r = 0.19, P = 0.25) was observed with SpO2. A moderate positive correlation was noted between PET and both weight (r = 0.44, P = 0.005) and height (r = 0.40, P = 0.01). In addition, there were significant differences in median PET across different age categories.

Conclusion:
The findings conclude that PET during CCT is significantly associated with heart rate and respiratory rate. An increase in these rates corresponds to a notable decrease in PET. Consequently, the study recommends minimizing scan delays in CCT for patients exhibiting higher heart rates.
STUDY STUDY OF SCIENCE LITERACY ABILITY OF CHEMISTRY PRE-SERVICE TEACHERS IN HYDROPONICS PRACTICUM
Authors: Bahriah Evi Sapinatul , Siti Suryaningsih  , Ivan Muhammad Maful  
Published: December 2024

The ability of scientific literacy of indonesian student categorized as low. One of the factor that contribute is that the ability of a scientific literacy of a teacher. The hydroponics practical in a biotechnology’s subject, can be measure the ability of scientific literacy of a student because there is a science process in it. The aim of this reasearch is to determine the ability of scientific literacy of chemisty pre-service Teachers for the knowledge and competency’s aspects in a hydroponics topic. The method that used in this reasearch was quantitative descriptive analysis and the technique of data collection by spreading the instrument in a purposive sampling technique to 50 chemisty pre-service teachers. The instrment that used was 10 items of essay questions. The data was analyse with a scoring method and then will change it into a percentage. Based on the reasearch, the ability of scientific literacy of a student for knowledge’s aspect is 68.5% and for the competency is 62.2%. From that data, it can conclude that the ability of scientific literacy of chemistry chemisty pre-service teachers for knowledge and comptency aspects categorized good.
THE RELATIONSHIP OF METACOGNTIVE KNOWLEDGE WITH METACOGNITIVE AWARENESS IN STUDENTS
Authors: Parestu Bina Putri , Milama Burhanudin , Fairusi Dila 
Published: December 2024

The 2013 curriculum requires students to demonstrate metacognitive proficiency. The alignment of knowledge and metacognitive awareness can assist students in achieving the learning objectives in the national curriculum. This study aimed to ascertain whether there was a correlation between metacognitive knowledge and metacognitive awareness among students. This study employed a correlational design research methodology. The instruments used to gather data including a set of 5 questions involved in testing students’ metacognitive knowledge. Meanwhile, The Metacognition Awareness Inventory (MAI) which comprised of 52 items was employed to assess metacognitive awareness. The correlation between metacognitive knowledge and awareness can be measured using the Product Moment correlation coefficient. The findings of this study indicated that there was a positive correlation between metacognitive knowledge and awareness yet it was relatively low (0.110).
Visual Instruction Tuning for Drone Accident Forensics
Authors: Editya Arda Surya , Ahmad Tohari , Studiawan Hudan 
Published: December 2024

The increasing use of drones in both commercial and personal use has led to a growing demand for effective forensic analysis following drone-related accidents. This research focuses on improving forensic analysis through the development of LLaVAFor, a fine-tuned version of the Large Language and Vision Assistant (LLaVA) model. The objective of this study is to enhance the interpretability of visual instruction tuning for drone accident forensics. LLaVAFor was developed by fine-tuning LLaVA via a specialized dataset of drone accident scenarios. The model's performance was evaluated via the BLEU score, a metric commonly used to assess machine translation and natural language processing models. The results demonstrated that LLaVAFor achieved superior BLEU scores compared with baseline models such as LLaVA, Google Gemini, and ChatGPT. It demonstrates its ability to provide more accurate and contextually relevant analyses. The key innovation in LLaVAFor is its ability to explain forensic findings in the context of drone accidents, making it a valuable tool for investigators. The results show that the model's fine-tuning process on drone-specific datasets enables it to offer detailed, domain-specific insights, improving the accuracy and reliability of forensic analyses in this field. Through these advancements, LLaVAFor represents a step forward in the integration of AI into drone accident investigations. Doi: 10.28991/HIJ-2024-05-04-01 Full Text: PDF