AB0870-HPR GLOBAL TRENDS IN PRP AND OSTEOARTHRITIS: A BIBLIOMETRIC AND VISUALIZED STUDY
Authors: Qiu Y. , Zhang Y. , Wen L. 
Published: May 2021

Background:Osteoarthritis (OA) is a serious disease, which is one of the main causes of joint pain and body dysfunction, raising serious economic and social burden. In recent years, there are tremendous articles on the treatment of osteoarthritis, platelet rich plasma (PRP) is one of the new trends in the treatment of osteoarthritis.Objectives:The purpose of this study is to explore the development trend of PRP related osteoarthritis study and grasp the hot spots and directions in this field.Methods:Publications focusing on PRP related osteoarthritis research from 2001 to 2020 were retrieved from Web of Science (WoS) and Science Citation Index-Expanded (SCIE) database. The retrieving methods were as follow: (theme = platelet rich plasma arthritis OR theme = platelet rich plasma osteoarthritis OR theme = platelet rich plasma cartilage OR theme = platelet rich plasma knee OR theme = platelet rich plasma orthopedic OR theme = platelet rich plasma orthopaedic OR theme = platelet rich plasma articular OR theme = platelet rich plasma joint OR theme = platelet rich plasma tendon). Publications were analyzed only when type is articles or reviews. The VOS viewer was used for the generation of bibliographic coupling and visualized study.Results:A total of 2847 publications were retrieved, including 2636 articles and reviews. Before 2000, there were only 15 relevant papers, which were not included in the specific analysis. It is clear that the number of publications on PRP related OA study is increasing every year, a total of 398 articles or reviews were published in 2020. The United States is the leading country in this field, with a number of 932 publications (35.4%), followed by Italy (304 publications, 11.5%) and China (294 publications, 11.2%). The most prevalent areas of PRP related OA research were orthopedics (1013 papers, 38.4%), sports science (651 papers, 24.7%) and surgery (475 papers,18.0%). The top 3 journal that published the most PRP related OA study is American Journal of Sports Medicine (153 papers, 5.8%), Arthroscopy: The Journal of Arthroscopic & Related Surgery (95 papers, 3.6%), Journal of Orthopaedic Research (83 papers, 3.1%). The Harvard University (96 papers, 3.6%), Hospital for Special Surgery (83 papers, 3.1%) and University of London (75 papers, 2.8%) is the top 3 institution that published the most articles or reviews. Filardo G from Italy published the most articles or reviews (52, 2.0%) in this area, followed by Maffulli N from the UK (49 publications, 1.9%) and Kon E from Italy (46, 1.7%). PRP related OA study can be divided into five categories: intra-articular treatment study, clinical trials related study, soft tissue repairment study, gene and molecular biology study, regeneration and implantation study.Conclusion:Publications on PRP related OA study is increasing according to the analysis on current global trends. The United States is now the leading country in this field, with the largest number and the highest quality of publications. Among the five cluster of PRP related OA studies, “intra-articular treatment study” and “regeneration and implantation study” are considered to be the current research hotspots in the PRP related OA field.References:[1]Foster T E, Puskas B L, Mandelbaum B R, et al. Platelet-rich plasma: from basic science to clinical applications.[J]. American Journal of Sports Medicine, 2009, 37(11):2259-2272.Disclosure of Interests:None declared