bluuebunny/crossref_metadata_2025_split huggingface dataset:
The call to recognition in the Canterbury Tales
Authors: Ashe Laura 
Published: January 2025

Abstract
This chapter begins by reviewing the modern philosophical debate about recognition, following Hegel. It then has three subsections: the first, ‘Walter and Griselda: The master and the servant’, pursues a close analysis of the Clerk’s Tale in light of Hegel’s famous description of the ‘desiring consciousness’ and the ‘struggle for recognition’; it is argued that with the narrative of his tale, Chaucer not only anticipates Hegel’s foundational structure of subjectivity, but also foreshadows many of the criticisms of Hegel’s theories that have followed in modern philosophical discussion of recognition. The second section, ‘“Wommen desiren to have sovereynetee”: The Wife of Bath’s struggle for recognition’, discusses the Wife of Bath as an exploration of the philosophy of recognition, in light of the misogyny embedded in Hegel’s theories and exposed in the critique of Judith Butler and others. The third, ‘“Who, in this plurality, comes first?” Levinasian ethics and the Franklin’s Tale’ turns to consider the Franklin’s Tale in light of Emmanuel Levinas’ adaptation and rejection of Hegel’s theory of recognition, embodied in the encounter with the Other. It is argued that where Levinas too consigned women to the status of ‘other’, Chaucer in contrast uses similar structures of subjectivity and accountability—and ‘response-ability’—to show his female protagonist, Dorigen, developing a new kind of agency and subjectivity.
The Book of the Duchess and the problem of other minds
Authors: Ashe Laura 
Published: January 2025

Abstract
This chapter begins with Wittgenstein’s account of our difficulty expressing subjective experience in language, and our playing of a ‘language-game’ of communication whereby signs stand in for effectively (albeit not actually) non-existent Somethings—such as pain—‘about which nothing can be said’. In light of this it offers a close reading of Chaucer’s major source for the Book of the Duchess, Guillaume de Machaut’s Jugement dou Roy de Behaingne, and moves to an analysis of Chaucer’s work as an exploration of Wittgenstein’s ideas. It is argued that while Machaut playfully simulates a world in which pain is communicable and commensurate, under a controlling subjectivity, Chaucer’s adaptation of the same themes results in an exploration of the limits of subjectivity and of empathy, in a world of human plurality in which the different ‘languages’ of subjective experience can only be combined in the language-game.
‘The Northern Separatists’
Authors: Keo Bernard Z 
Published: January 2025

Abstract
Following their failed attempts to stop the Federation, Peranakan political activists in Penang decided the only viable course of action was to secede and reconstitute the Straits Settlements. Through detailed analysis of the petition presented to the Colonial Office by the Penang secession committee, records produced by British colonial administrators, and newspaper reports, this chapter demonstrates that the secession movement (1948–51) was led by Peranakan putting forward an alternative cosmopolitan imagination of the nation-state from the one implicit in the Federation. In doing so, it challenges the established narrative that the movement was led by a coalition of Penang’s commercial elites seeking to restore Penang to imperial control. Conducting this re-evaluation of the secession movement and placing it within a broader trajectory of Peranakan ideas about the nation reveals a more progressive agenda than has previously been acknowledged, one centred on self-government and equal rights for all those residing in Malaya regardless of race, creed, or nationality.
Uncharted Waters
Authors: Keo Bernard Z 
Published: January 2025

Abstract
Having had their requests to leave the Federation rejected, Peranakan leaders changed tack and sought to reform the Federation from within. Between 1951 and 1955, they joined the myriad political parties that sprung up in response to the colonial government’s decision to introduce elections to Malaya. Focussing on Peranakan involvement in the Malayan Chinese Association, the Independence of Malaya Party (IMP), the Progressive Party, the Penang Radical Party, and Parti Negara, this chapter investigates the community’s attempts to secure a fair and equitable Malaya through the democratic process. As communal parties increasingly came to dominate the political landscape, the Peranakan community factionalized over the best course of action: committing to intercommunal parties and attempting to progressively build their bases or embracing communal politics to win power before implementing reforms. Regardless of their political beliefs, Peranakan actors maintained memberships in both intercommunal and communal political parties. This was political pragmatism on the part of the community which was willing to use any means at their disposal to secure a more inclusive Malayan nation.
‘Merdeka for All’
Authors: Keo Bernard Z 
Published: January 2025

Abstract
This chapter reinterprets the final lead up to merdeka (independence) through the lens of the Peranakan as a means of looking beyond dominant historical narratives that privilege the perspectives of the Alliance and the British in Malay(si)a's independence process. It focusses first on the revival of the Penang secession movement from 1953 to 1956 in response to the collapse of intercommunal political parties following the 1955 general elections and the entrenchment of communalism as the default mode of politics in the Federation. The secession movement’s ultimate collapse in the wake of opposition from the Alliance government, the British colonial government, and Whitehall resulted in the Peranakan shifting tactics. From 1956 to 1957, Peranakan leaders focussed their efforts on lobbying the Reid Constitutional Commission with the intention of securing provisions within the constitution for equal rights and the maintenance of dual citizenship. This chapter challenges existing interpretations of Peranakan efforts during this period as regressive acts designed to restore their privileged position in Malayan society, contending instead that these actions were in service of securing rights for themselves and other minority communities as protection against an ethnonationalist state.
Association of binge alcohol use with functional outcomes among individuals with COVID-19 infection
Authors: Tong Sebastian T , Gottlieb Michael , Ebna Mannan Imtiaz , Zheng Zihan , Sinha Manisha , Santangelo Michelle , Gatling Kristyn , Kean Efrat , Watts Phillip , Wang Ralph , Montoy Juan Carlos , Idris Ahamed , MacDonald Samuel , Huebinger Ryan , Hill Mandy , O’Laughlin Kelli N , Gentile Nicole L , Dorney Jocelyn , Malicki Caitlin , Elmore Joann G , Diaz Roldan Kate , Chan Gary , Lin Zhenqiu , Weinstein Robert A , Stephens Kari A 
Published: January 2025

Abstract

Aims
Alcohol consumption along with negative sequelae from excess alcohol intake increased during the COVID-19 pandemic. We evaluated the association between binge alcohol use and long-term functional outcomes among COVID-19-positive individuals.

Methods
Using a prospective, longitudinal, multisite cohort study design, we evaluated the association between binge alcohol use and mental and physical functional outcomes using Patient-Reported Outcomes Measurement Information System (PROMIS)-29 scores three and six months postinfection. Eligible patients were those who presented with COVID-19-like symptoms, tested positive for COVID-19, and completed a three-month survey. Binge drinking was identified at the time of infection using the Tobacco, Alcohol, Prescription medication and other Substance use screener. Generalized estimating equation models, adjusted for demographic characteristics, social determinants of health, substance use, comorbidities, and COVID-19 vaccine status, were used to assess the association between binge alcohol use and mental and physical functional outcomes.

Results
Of 3529 individuals, 23.7% screened positive for binge drinking. At three months, prior self-reported binge drinking was associated with differences in physical function [estimate: 1.08; 95% confidence interval (CI) 0.44, 1.71], pain interference (estimate: −0.86; 95% CI −1.57, −0.15), and physical health (estimate: 1.09; 95% CI 0.43, 1.75). At six months, no associations were found between binge drinking and outcomes.

Conclusions
Binge alcohol use before COVID-19 infection was associated with statistically significant but clinically irrelevant improvements in function at three months, which were not sustained at six months. Postinfectious and postpandemic stressors may have played a larger impact on functional outcomes than binge alcohol use. A higher frequency of binge drinking and its association with functional outcomes, particularly among individuals with COVID-19 warrants further study.
Rates and Predictors of Performance Validity Test Failure in Adults Treated for Post-COVID-19 Condition: a Brief Report
Authors: Clark Phoebe A , Horn Samantha , Wang Natalie , Lyketsos Constantine G , Parker Ann M , Oh Esther S , Vannorsdall Tracy D 
Published: January 2025

Abstract

&gt;Objective
Cognitive dysfunction is a common symptom of post-COVID-19 condition (PCC). Few studies have examined rates and predictors of cognitive performance validity test (PVT) failure in patients seeking treatment for PCC.

&gt;Methods
We report the rates of PVT failure in 323 patients who received care in a long-COVID-19 clinic for any post-COVID-19 health concern and underwent routine telephone cognitive testing that included two embedded PVTs. Binary logistic regressions examined the demographic, illness, and psychological variables associated with PVT failure.

&gt;Results
The prevalence of single PVT failure ranged from 4.7% to 26.1% whereas failure on both PVTs occurred in just 6.3%. Illness characteristics, subjective cognitive dysfunction, and most demographic and psychological variables were unrelated to single PVT failure. Males and those with anxiety were more likely to fail both PVTs.

&gt;Conclusion
Failure across multiple PVTs was not common and was unrelated to COVID-19 severity or cognitive complaints.
Behavioural variation in background colour matching and the effect of social environment in rock-pool mosquitoes
Authors: Cordeschi Giulia , Porretta Daniele , Canestrelli Daniele 
Published: January 2025

Abstract
Several animal species conceal themselves from potential predators by actively choosing environmental patches that best match body coloration and chromatic patterns. Growing evidence shows that a variety of contexts and conditions can affect this background choice behaviour, yet the extent of this variety remains largely underexplored. Here, we explore the effect of disturbance and social environment on background colour choice behaviour in the rock-pool mosquito Aedes mariae. We exposed single individuals and groups of individuals to experimental arenas made of dark and bright patches and recorded the colour preferences of individuals when alone and within groups, and before and after a disruptive event. We found a marked prevalence of individuals favouring a dark background and an among-individual variation in choice over replicated trials. Moreover, we observed a non-significant effect of disturbance but a significant role of the social environment. In fact, being caged in groups significantly increased the proportion of mosquitoes choosing the dark background. Our results provide strong evidence of a background colour choice in Ae. mariae, a density dependence of this choice, and a non-negligible inter-individual variation in this behaviour. Overall, these findings offer intriguing insights into background choice behavioural variation and flexibility of mosquitoes.
Divergent effect of predator presence on gut morphology shows parallel patterns in congeneric species
Authors: Gorini-Pacheco Bruno , Mazzoni Rosana , Marques Piatã , Neres-Lima Vinicius , Zandonà Eugenia 
Published: January 2025

Abstract
Understanding the mechanisms driving parallel evolution across species and populations is fundamental to evolutionary biology. We investigated the parallel phenotypic divergence of trophic morphology in response to predation pressure in two recently described congeneric species of poeciliid fish, Phalloceros harpagos and Phalloceros anisophallos. By comparing populations from high and low predation environments with similar environmental characteristics, we aimed to isolate the effect of predation on trophic traits while controlling the effect of other sources of environmental variation. We found that populations experiencing high predation pressure had shorter guts, which is indicative of a more carnivorous diet, compared to populations in low predation environments. This parallel divergence in trophic morphology suggests that predation indirectly influences per-capita resource availability, driving convergent ecological characteristics in different species of Phalloceros. Our study highlights the importance of considering indirect effects of predation on trophic traits and provides insights into the mechanisms underlying parallel phenotypic divergence. This is one of the few field studies that has directly tested parallel phenotypic divergence, within and between species, focusing on one agent of selection and minimizing the confounding effect of other environmental sources of variation.
Spatially adaptive variable screening in presurgical functional magnetic resonance imaging data analysis
Authors: Hu Yifei , Jeng Xinge Jessie 
Published: January 2025

ABSTRACT
Accurate delineation of functional brain regions adjacent to tumors is imperative for planning neurosurgery that preserves critical functions. Functional magnetic resonance imaging (fMRI) plays an increasingly pivotal role in presurgical counseling and planning. In the analysis of presurgical fMRI data, the impact of false negatives on patients surpasses that of false positives because failure to identify functional regions and unintentionally resecting critical tissues can result in severe harm to patients. This paper introduces a novel metric, the Bayesian missed discovery rate (BMDR), designed for controlling false negatives within the voxel-specific mixture model. Building on the BMDR metric, we propose a new variable screening procedure that not only ensures effective control of false negatives but also capitalizes on the spatial structure of fMRI data. In comparison to existing statistical methods in fMRI data analysis, our new procedure directly regulates false negatives at a desirable level and is entirely data-driven. Moreover, it significantly differs from current false-negative control procedures by incorporating spatial information. Numerical examples demonstrate that the new method outperforms several state-of-the-art methods in retaining signal voxels, particularly the subtle ones at the boundaries of functional regions, while achieving a cleaner separation of functional regions from background noise. These findings hold promising implications for planning function-preserving neurosurgery.
Experienced-based co-design for cardiovascular and chronic disease research
Authors: Koirala Binu , Benjasirisan Chitchanok , Lim Arum , Moore Robyn , Dennison Himmelfarb Cheryl R , Davidson Patricia M 
Published: January 2025

Abstract
The participatory co-design method has received significant attention recently. Experience-based co-design is an approach that enables patients (service users) and healthcare providers (service delivers) to co-design services and care pathways in partnership to improve health outcomes based on their experience. Traditionally, it was used as a quality improvement technique. Yet, it is a valuable participatory research design that can help improve health outcomes and be applied in nursing research. This paper will discuss its application in research among people living with cardiovascular multimorbidity and its practicalities, usability, and impact on cardiovascular and chronic disease research and models of care.
Genome-wide association study of salicylic acid provides genetic insights for tea plant selective breeding
Authors: Deng Xiuling , Huang Dejun , Wang Yihan , An Hongwei , Bai Dingchen , Wang Xiaojing , Niu Suzhen , Song Xiaoming 
Published: January 2025

Abstract
Salicylic acid (SA) is a phenolic phytohormone widely believed to regulate plant growth and stress response. Despite its significance, the genetic basis of SA-mediated resistance to biotic stressors in tea plants is little understood. Our study investigated the genetic diversity, population structure, and linkage disequilibrium (LD) patterns of 299 tea accessions using 79 560 high-quality single nucleotide polymorphisms (SNPs) obtained from genotyping-by-sequencing (GBS) data. Our genome-wide association study identified CSS0033791.1, an essential gene encoding 9-cis-epoxycarotenoid dioxygenase (CsNCED1), which catalyzes a vital step in abscisic acid (ABA) biosynthesis. Exogenous ABA treatment and transgenic overexpression of the CsNCED1 gene lowered SA content in the respective tea plants by inhibiting the expression of the ICS gene. Further analysis revealed that ABA could reduce the expression levels of the SA receptor gene (NPR1) and NPR1 target genes (PR1 and WRKY18), increasing the plant’s susceptibility to biotic stressors. Furthermore, the feeding behavior of Spodoptera litura (S. litura) revealed that the insect bite area on transgenic leaves was substantially more extensive than that in wild-type, implying that the CsNCED1 gene had a negative regulatory role in SA-mediated immune response. This study thus provides the foundation for future insect resistance breeding, sustainable tea plant resource usage, and molecular marker-assisted (MAS) tea plant breeding.
Flavonoids as key players in cold tolerance: molecular insights and applications in horticultural crops
Authors: Li Jiaxin , Yu Qinhan , Liu Chang , Zhang Ningbo , Xu Weirong 
Published: January 2025

Abstract
Cold stress profoundly affects the growth, development, and productivity of horticultural crops. Among the diverse strategies plants employ to mitigate the adverse effects of cold stress, flavonoids have emerged as pivotal components in enhancing plant resilience. This review was written to systematically highlight the critical role of flavonoids in plant cold tolerance, aiming to address the increasing need for sustainable horticultural practices under climate stress. We provide a comprehensive overview of the role of flavonoids in the cold tolerance of horticultural crops, emphasizing their biosynthesis pathways, molecular mechanisms, and regulatory aspects under cold stress conditions. We discuss how flavonoids act as antioxidants, scavenging reactive oxygen species (ROS) generated during cold stress, and how they regulate gene expression by modulating stress-responsive genes and pathways. Additionally, we explore the application of flavonoids in enhancing cold tolerance through genetic engineering and breeding strategies, offering insights into practical interventions for improving crop resilience. Despite significant advances, a research gap remains in understanding the precise molecular mechanisms by which specific flavonoids confer cold resistance, especially across different crop species. By addressing current knowledge gaps, proposing future research directions, and highlighting implications for sustainable horticulture, we aim to advance strategies to enhance cold tolerance in horticultural crops.
Laughing through the Mask in Invisible Man
Authors: Paustian Megan Cole 
Published: January 2025

Abstract
What is the relationship among Blackness, whiteness, and laughter? For Ralph Ellison, race is at the heart of “the American joke”; his phrase suggests that humor is somehow fundamental to the American story. It is certainly fundamental to his novel, Invisible Man (1952). While much scholarship has addressed the novel’s humor—how it makes readers laugh—the laughter of characters has been underexplored. From start to finish, the narrative is punctuated with scenes of laughter, which crop up at every major turning point in the unnamed narrator’s journey. While he encounters laughter that is racist and belittling, he also reckons with its creative, communal forms. By tracing his journey through the trope of laughter and placing the novel in conversation with theories of Black humor, this essay reveals how the laugh operates as a strategy of defense and defiance, at once protective and resistant. Like the mask of meekness, exemplified by the narrator’s grandfather, Black laughter is a technique for navigating the tensions and threats of American life. It can cloak aggression and ease white fears, but it communicates more ambiguously than the mask, leaving observers in a state of uncertainty. The novel suggests that Black laughter flirts with power in a way that unsettles white consciousness and expands the mask’s terrain of resistance. Zeroing in on laughter itself reveals its role in day-to-day navigations of the color line while also adding nuance to more general theories of humor.
Functional germline variants in DNA damage repair pathways are associated with altered survival in adults with glioma treated with temozolomide
Authors: Guerra Geno , Wendt George , McCoy Lucie , Hansen Helen M , Kachuri Linda , Molinaro Annette M , Rice Terri , Guan Victoria , Capistrano Lianne , Hsieh Allison , Kalsi Veruna , Sallee Jaimie , Taylor Jennie W , Clarke Jennifer L , Almaraz Eduardo Rodriguez , Wiencke John K , Eckel-Passow Jeanette E , Jenkins Robert B , Wrensch Margaret , Francis Stephen S 
Published: January 2025

Abstract

Background
Temozolomide (TMZ) treatment has demonstrated, but variable, impact on glioma prognosis. This study examines associations of survival with DNA repair gene germline polymorphisms among glioma patients who did and did not have TMZ treatment. Identifying genetic markers which sensitize tumor cells to TMZ could personalize therapy and improve outcomes.

Methods
We evaluated TMZ-related survival associations of pathogenic germline SNPs and genetically predicted transcript levels within 34 DNA repair genes among 1504 glioma patients from the UCSF Adult Glioma Study and Mayo Clinic whose diagnoses spanned pre- and post-TMZ eras within the major known glioma prognostic molecular subtypes.

Results
Among those who received TMZ, 5 SNPs were associated with overall survival, but not in those who did not receive TMZ. Only rs2308321-G, in MGMT, was associated with decreased survival (HR=1.21, p=0.019) for all glioma subtypes. Rs73191162-T (near UNG), rs13076508-C (near PARP3), rs7840433-A (near NEIL2), and rs3130618-A (near MSH5) were only associated with survival and TMZ treatment for certain subtypes, suggesting subtype-specific germline chemo-sensitization.
Genetically predicted elevated compared to normal brain expression of PNKP was associated with dramatically worse survival for TMZ-treated patients with IDH-mutant and 1p/19q non-codeleted gliomas (p=0.015), with a median difference of over 70 months in overall survival times. Similarly, NEIL2 and TDG expressions were associated with altered TMZ-related survival only among certain subtypes.

Conclusions
Functional germline alterations within DNA repair genes were associated with TMZ sensitivity, measured by overall survival, among adults with glioma, these variants should be evaluated in prospective analyses and functional studies.
Mimickers of Pituitary Tumors
Authors: Perez-Guzman M Citlalli , Szuman Gabriela , Altwijri Abdulrahman , Shek Kevin , Asa Sylvia L , Ezzat Shereen 
Published: January 2025

Abstract
Enlargement of the pituitary gland and/or its surrounding structures on brain or sellar imaging is a frequent finding. The distinction between clinically relevant and incidental changes can be challenging. Further, the assumption that sellar lesions reflect a true neoplasm must be rigorously questioned to avoid inappropriate treatment or unnecessary surveillance plans. Here we review wide-ranging conditions that can mimic primary pituitary tumors. We outline a suggested approach to rational decision-making.