bluuebunny/crossref_metadata_2025_split huggingface dataset:
Umsetzung anästhesiologischer Fast-Track-Maßnahmen bei kolorektalen Resektionen
Authors: Willis M. A. , Thudium M. , van Beekum C. J. , Söhle M. , Coburn M. , Kalff J. C. , Vilz T. O. 
Published: November 2021

Zusammenfassung
Einleitung
Beim Fast-Track(FT)-Konzept handelt es sich um multimodale, interdisziplinäre Maßnahmen zur perioperativen Patientenbetreuung zur Reduktion postoperativer Komplikationen. Trotz guter Evidenz erscheint die Umsetzung verbesserungswürdig, wobei sich nahezu alle Untersuchungen ungeachtet des interdisziplinären Aspektes auf die Implementierung der chirurgischen Module fokussieren. Die Adhärenz zu den anästhesiologischen Maßnahmen (präoperative Patientenoptimierung, Prämedikation, Volumen- und Wärmemanagement, Schmerztherapie) ist hingegen nur unzureichend untersucht. Um den Status quo zu erfassen, wurde eine Umfrage zur Umsetzung der anästhesiologischen FT-Bausteine unter den Mitgliedern der Deutschen Gesellschaft für Anästhesiologie und Intensivmedizin (DGAI) durchgeführt und analysiert, wo mögliches Verbesserungspotenzial besteht.

Methoden
Mithilfe des Online-Umfragetools SurveyMonkey® wurden 28 Fragen zur perioperativen anästhesiologischen Versorgung kolorektalchirurgischer Patienten an die Mitglieder der DGAI verschickt und die Adhärenz zu den FT-Maßnahmen analysiert.

Ergebnisse
Während einige der FT-Maßnahmen (Wärmemanagement, PONV-Prophylaxe) bereits routinemäßig umgesetzt sind, gibt es bei anderen Bausteinen eine Divergenz zwischen den aktuellen Empfehlungen und der klinischen Umsetzung. Besonders betroffen sind neben der Prämedikation insbesondere interdisziplinäre Maßnahmen (Prähabilitation) sowie Maßnahmen, die mehrere Schnittstellen (OP, Aufwachraum (AWR), Station) betreffen, wie beispielsweise Volumenmanagement oder perioperative Schmerztherapie

Fazit
Die anästhesiologischen Empfehlungen des FT-Konzepts werden in Deutschland nur teilweise umgesetzt. Hiervon sind insbesondere die interdisziplinären Bausteine sowie Maßnahmen an den Schnittstellen OP-AWR-Station betroffen. Die Bildung eines interdisziplinären FT-Teams und die interdisziplinäre Ausarbeitung von SOP können die Adhärenz optimieren, was wiederum das kurz- und langfristige Outcome der Patienten verbessert.
A note on cut-elimination for classical propositional logic
Authors: Pulcini Gabriele 
Published: November 2021

AbstractIn Schwichtenberg (Studies in logic and the foundations of mathematics, vol 90, Elsevier, pp 867–895, 1977), Schwichtenberg fine-tuned Tait’s technique (Tait in The syntax and semantics of infinitary languages, Springer, pp 204–236, 1968) so as to provide a simplified version of Gentzen’s original cut-elimination procedure for first-order classical logic (Gallier in Logic for computer science: foundations of automatic theorem proving, Courier Dover Publications, London, 2015). In this note we show that, limited to the case of classical propositional logic, the Tait–Schwichtenberg algorithm allows for a further simplification. The procedure offered here is implemented on Kleene’s sequent system G4 (Kleene in Mathematical logic, Wiley, New York, 1967; Smullyan in First-order logic, Courier corporation, London, 1995). The specific formulation of the logical rules for G4 allows us to provide bounds on the height of cut-free proofs just in terms of the logical complexity of their end-sequent.
Remarks on weak amalgamation and large conjugacy classes in non-archimedean groups
Authors: Malicki Maciej 
Published: November 2021

AbstractWe study the notion of weak amalgamation in the context of diagonal conjugacy classes. Generalizing results of Kechris and Rosendal, we prove that for every countable structure M, Polish group G of permutations of M, and $$n \ge 1$$

n
≥
1

, G has a comeager n-diagonal conjugacy class iff the family of all n-tuples of G-extendable bijections between finitely generated substructures of M, has the joint embedding property and the weak amalgamation property. We characterize limits of weak Fraïssé classes that are not homogenizable. Finally, we investigate 1- and 2-diagonal conjugacy classes in groups of ball-preserving bijections of certain ordered ultrametric spaces.
Temporal variations of net Kuroshio transport based on a repeated hydrographic section along 137°E
Authors: Kawakami Yuma , Kojima Atsushi , Murakami Kiyoshi , Nakano Toshiya , Sugimoto Shusaku 
Published: November 2021

AbstractTemporal variations of net Kuroshio transport are examined for 1972–2018 based on a repeated hydrographic section along 137°E, which is maintained by the Japan Meteorological Agency. The net Kuroshio transport obtained by integration of geostrophic current velocity relative to 1000 dbar depth fluctuates on inter-annual and decadal timescales. The predominant timescale of the net Kuroshio transport changes with time; the inter-annual variation is pronounced in 1972–1990 and 2000–2018, and the decadal variation is detected only before 2000. We find that a winter wind stress curl variation in the central North Pacific which reflects meridional movements of the Aleutian Low and intensity fluctuations of the North Pacific subtropical high on an inter-annual timescale and intensity fluctuations of the Aleutian Low on a decadal timescale, causes the net Kuroshio transport variation. In addition to the inter-annual and decadal variations, we further pointed out a bi-decadal-scale variation of the net Kuroshio transport and its possible link to the Aleutian Low intensity fluctuation. Moreover, our results indicate that during large net Kuroshio transport, sea surface temperature around the Kuroshio and Kuroshio Extension region tends to increase, resulting in vigorous upward sensible and latent heat release.
Crystal plasticity model of residual stress in additive manufacturing using the element elimination and reactivation method
Authors: Grilli Nicolò , Hu Daijun , Yushu Dewen , Chen Fan , Yan Wentao 
Published: November 2021

AbstractSelective laser melting is receiving increasing interest as an additive manufacturing technique. Residual stresses induced by the large temperature gradients and inhomogeneous cooling process can favour the generation of cracks. In this work, a crystal plasticity finite element model is developed to simulate the formation of residual stresses and to understand the correlation between plastic deformation, grain orientation and residual stresses in the additive manufacturing process. The temperature profile and grain structure from thermal-fluid flow and grain growth simulations are implemented into the crystal plasticity model. An element elimination and reactivation method is proposed to model the melting and solidification and to reinitialize state variables, such as the plastic deformation, in the reactivated elements. The accuracy of this method is judged against previous method based on the stiffness degradation of liquid regions by comparing the plastic deformation as a function of time induced by thermal stresses. The method is used to investigate residual stresses parallel and perpendicular to the laser scan direction, and the correlation with the maximum Schmid factor of the grains along those directions. The magnitude of the residual stress can be predicted as a function of the depth, grain orientation and position with respect to the molten pool. The simulation results are directly comparable to X-ray diffraction experiments and stress–strain curves.
Efficacy and safety comparison between 1927 nm thulium laser and 2940 nm Er:YAG laser in the treatment of facial atrophic acne scarring: a prospective, simultaneous spilt-face clinical trial
Authors: Lu Kune , Cai Suiqing 
Published: November 2021

AbstractAcne scarring is a common disfiguring complication of acne, and fractional lasers are widely applied in improving it. This study is to compare the efficacy and safety of fractional non-ablative 1927 nm thulium laser (FTL) and fractional ablative 2940 nm Er:YAG laser (FEL) in the treatment of acne scarring. Subjects with moderate or severe atrophic facial acne scarring received 3 sessions of FTL on the left side of face and FEL on the right side of face at an average interval of 4–6 weeks. Major assessments included Goodman&Baron quantitative global scarring grading system (GBS), self-rated improvement and satisfaction score. Twenty-seven subjects completed the study; for FTL side, average GBS decreased from 11.15 ± 5.04 at baseline to 7.07 ± 4.87 with an improvement percent of 36.54%; for FEL side, average GBS decreased from 10.81 ± 4.46 to 7.00 ± 4.07 with an improvement percent of 35.27%. Adverse effects include transient pain, erythema, edema, and increase of acne. No significant difference was found between two lasers. Both FTL and FEL improved atrophic acne scarring and were well-tolerated. Increase of acne during laser treatment may have a negative impact on efficacy. Trial registration number was NCT04813419 and date of registration was 19th, March, 2021, retrospectively registered.
Performance assessment of a low-complexity autoregressive Kalman filter for GNSS carrier tracking using real scintillation time series
Authors: Locubiche-Serra Sergi , Seco-Granados Gonzalo , López-Salcedo José A. 
Published: November 2021

AbstractIonospheric scintillation is one of the most challenging sources of errors in global navigation satellite systems (GNSS). It is an effect of space weather that introduces rapid amplitude and phase fluctuations to transionospheric signals and, as a result, it severely degrades the tracking performance of receivers, particularly carrier tracking. It can occur anywhere on the earth during intense solar activity, but the problem aggravates in equatorial and high-latitude regions, thus posing serious concerns to the widespread deployment of GNSS in those areas. One of the most promising approaches to address this problem is the use of Kalman filter-based techniques at the carrier tracking level, incorporating some a priori knowledge about the statistics of the scintillation to be dealt with. These techniques aim at dissociating the carrier phase dynamics of interest from phase scintillation by modeling the latter through some correlated Gaussian function, such as the case of autoregressive processes. However, besides the fact that the optimality of these techniques is still to be reached, their applicability for dealing with scintillation in real-world environments also remains to be confirmed. We carry out an extensive analysis and experimentation campaign on the suitability of these techniques by processing real data captures of scintillation at low and high latitudes. We first evaluate how well phase scintillation can be modeled through an autoregressive process. Then, we propose a novel adaptive, low-complexity autoregressive Kalman filter intended to facilitate the implementation of the approach in practice. Last, we provide an analysis of the operational region of the proposed technique and the limits at which a performance gain over conventional tracking architectures is obtained. The results validate the excellence of the proposed approach for GNSS carrier tracking under scintillation conditions.
Local-scale dispersal patterns and susceptibility to Dryocosmus kuriphilus in different Castanea species and hybrid clones: insights from a field trial
Authors: Castedo-Dorado Fernando , Álvarez-Álvarez Pedro , Cuenca Valera Beatriz , Lombardero María Josefa 
Published: November 2021

AbstractThe chestnut gall wasp Dryocosmus kuriphilus is a major insect pest affecting chestnut trees worldwide. Medium and long-term control of this pest can be improved by using resistant or less susceptible cultivars and hybrid clones. In addition, little is known about the local patterns of dispersal of the pest. We obtained data from trees of 3 chestnut species and 27 hybrid clones in a field trial in NW Spain with the aim of evaluating the susceptibility of the material to the gall wasp and identifying possible drivers of local spatial dispersal. In the first 3 years of the invasion by D. kuriphilus, the number of trees attacked and the number of galls on each tree were spatially clustered. Tree height significantly predicted both variables, suggesting that gall wasps may use visual cues to locate suitable host trees, at least in the early stage of invasion. Assessment of the susceptibility of hybrid clones/pure species must take concurrent indicators of infestation levels into account. We suggest the use of indices involving galls on shoots because these enable good assessment of the damage to chestnut trees. The study findings add to existing knowledge on the susceptibility of hybrid chestnut clones. We report, for the first time, two hybrid clones resistant to the pest and one hybrid clone which exhibited consistently low values for all of the indicators of infestation level. The results have important implications regarding selection of plant material for use in afforestation in Spain, where the current high rate of chestnut planting is expected to continue.
Dialectical logic or logical dialectics? The Polish discussion on the principle of non-contradiction (1946–1957)
Authors: Woźniak Monika 
Published: November 2021

AbstractThe discussion on the principle of non-contradiction (1946–1957) between Marxist and non-Marxist philosophers was one of the major philosophical discussions in Polish philosophy of this period. In my text, I carefully reconstruct this discussion and outline its relation to Soviet debates on the subject. I show that the change in Schaff’s position happened in the early 1950s under the combined influence of the Lvov–Warsaw School and the changes in the official Soviet position regarding formal logic. I discuss the aftermath following Schaff’s change in attitude towards the analytic tradition for the development of Polish philosophy, as well as the critique of this change by Jarosław Ładosz. In my reconstruction of the latter, I focus on the problem of the historical development of science. I refer to Ilyenkov’s critique of Schaff, opposing synchronic (“positivist”) and diachronic (“dialectical”) concepts of knowledge. As I argue, these opposing concepts of science can be seen as a genuine issue at stake in the Polish discussion as well, especially in the polemic between Schaff and Ładosz.
Optimal labor and capital utilization by financial firms: evidence from the German property and casualty insurance industry
Authors: Eling Martin , Lehmann Martin , Schaper Philipp 
Published: November 2021

AbstractMotivated by discussions whether financial firms use too much equity capital and labor, we analyze the input utilization in the German property and casualty (p/c) insurance industry in a newly constructed sample of firm-level data in the period 1956–2019. An earlier study for the U.S. (Cummins and Nini, J Financial Serv Res 21(1–2):15–53, 2002) finds that p/c insurers over-utilize capital. Compared to this study, our large historical dataset exhibits less heterogeneity and thus allows a cleaner identification of the impact of firm characteristics on input factor utilization. We show that German p/c insurers have substantial cost savings potential and that labor input is the main driver of inefficiency. We also document severe differences in firm characteristics driving the utilization of labor. Our results contribute to both the academic discussion on productivity and efficiency in financial services as well as to the political discussion on the future of work and capital regulation in this sector.
The Advent and Fall of a Vocabulary Learning Bias from Communicative Efficiency
Authors: Carrera-Casado David , Ferrer-i-Cancho Ramon 
Published: November 2021

AbstractBiosemiosis is a process of choice-making between simultaneously alternative options. It is well-known that, when sufficiently young children encounter a new word, they tend to interpret it as pointing to a meaning that does not have a word yet in their lexicon rather than to a meaning that already has a word attached. In previous research, the strategy was shown to be optimal from an information theoretic standpoint. In that framework, interpretation is hypothesized to be driven by the minimization of a cost function: the option of least communication cost is chosen. However, the information theoretic model employed in that research neither explains the weakening of that vocabulary learning bias in older children or polylinguals nor reproduces Zipf’s meaning-frequency law, namely the non-linear relationship between the number of meanings of a word and its frequency. Here we consider a generalization of the model that is channeled to reproduce that law. The analysis of the new model reveals regions of the phase space where the bias disappears consistently with the weakening or loss of the bias in older children or polylinguals. The model is abstract enough to support future research on other levels of life that are relevant to biosemiotics. In the deep learning era, the model is a transparent low-dimensional tool for future experimental research and illustrates the predictive power of a theoretical framework originally designed to shed light on the origins of Zipf’s rank-frequency law.
In silico Methods for Identification of Potential Therapeutic Targets
Authors: Zhang Xuting , Wu Fengxu , Yang Nan , Zhan Xiaohui , Liao Jianbo , Mai Shangkang , Huang Zunnan 
Published: November 2021

AbstractAt the initial stage of drug discovery, identifying novel targets with maximal efficacy and minimal side effects can improve the success rate and portfolio value of drug discovery projects while simultaneously reducing cycle time and cost. However, harnessing the full potential of big data to narrow the range of plausible targets through existing computational methods remains a key issue in this field. This paper reviews two categories of in silico methods—comparative genomics and network-based methods—for finding potential therapeutic targets among cellular functions based on understanding their related biological processes. In addition to describing the principles, databases, software, and applications, we discuss some recent studies and prospects of the methods. While comparative genomics is mostly applied to infectious diseases, network-based methods can be applied to infectious and non-infectious diseases. Nonetheless, the methods often complement each other in their advantages and disadvantages. The information reported here guides toward improving the application of big data-driven computational methods for therapeutic target discovery.Graphical abstract
Wavelength, dose, skin type and skin model related radical formation in skin
Authors: Meinke M. C. , Busch L. , Lohan S. B. 
Published: November 2021

AbstractThe exposure to sun radiation is indispensable to our health; however, a long-term and high exposure could lead to cell damage, erythema, premature skin aging, and promotion of skin tumors. An underlying pathomechanism is the formation of free radicals which may induce oxidative stress at elevated concentrations. Different skin models, such as porcine-, murine-, human- ex vivo skin, reconstructed human skin (RHS) and human skin in vivo, were investigated during and after irradiation using X- and L-band EPR spectroscopy within different spectral regions (UVC to NIR). The amount of radical formation was quantified with the spin probe PCA and the radical types were measured ex vivo with the spin trap DMPO. The radiation dose influences the types of radicals formed in the skin. While reactive oxygen species (ROS) are always pronounced at low doses, there is an increase in lipid oxygen species (LOS) at high doses. Furthermore, the radical types arise independent from the irradiation wavelength, whereas the general amount of radical formation differs with the irradiation wavelength. Heat pre-stressed porcine skin already starts with higher LOS values. Thus, the radical type ratio might be an indicator of stress and the reversal of ROS/LOS constitutes the point where positive stress turns into negative stress.Compared to light skin types, darker types produce less radicals in the ultraviolet, similar amounts in the visible and higher ones in the infrared spectral region, rendering skin type-specific sun protection a necessity.
The societal impact of electronic sport: a scoping review
Authors: Riatti Paolo , Thiel Ansgar 
Published: November 2021

AbstractCompetitive computer gaming, known as electronic sport or esport, is growing and professionalizing profoundly during the past years with experts struggling to allocate it in society. This scoping review explores existing evidence and identifies potential societal impact of esport by applying the Mapping Elite Sports Societal Impact Model. Main findings included insights on the motivation of passive and active esport consumption, beneficial socializing, pedagogical or educational aspects, hegemonial clinical pictures in esport, differing popularity regarding demographics and games, and potential interference of the esport economy in traditional sports. The findings implicate a paradigm shift in the world of sport. It can be stated that esport affects society in a positive and a negative way, although the fragmented body of research has only given superficial evidence so far. Future research needs to go into detail regarding the peculiarities and find approaches of isolating the positive aspects, while reducing the negative spin-offs and allow a well-regulated handling of esport on a broad societal level.
A trim problem formulation for maximum control authority using the Attainable Moment Set geometry
Authors: Varriale Carmine , Voskuijl Mark 
Published: November 2021

AbstractThis paper presents a generic trim problem formulation, in the form of a constrained optimization problem, which employs forces and moments due to the aircraft control surfaces as decision variables. The geometry of the Attainable Moment Set (AMS), i.e. the set of all control forces and moments attainable by the control surfaces, is used to define linear equality and inequality constraints for the control forces decision variables. Trim control forces and moments are mapped to control surface deflections at every solver iteration through a linear programming formulation of the direct Control Allocation algorithm. The methodology is applied to an innovative box-wing aircraft configuration with redundant control surfaces, which can partially decouple lift and pitch control, and allow direct lift control. Novel trim applications are presented to maximize control authority about the lift and pitch axes, and a “balanced” control authority. The latter can be intended as equivalent to the classic concept of minimum control effort. Control authority is defined on the basis of control forces and moments, and interpreted geometrically as a distance within the AMS. Results show that the method is able to capitalize on the angle of attack or the throttle setting to obtain the control surfaces deflections which maximize control authority in the assigned direction. More conventional trim applications for minimum total drag and for assigned angle of elevation are also explored.