bluuebunny/crossref_metadata_2025_split huggingface dataset:
Myxoma of the Small Bowel in a 47-Year-Old Woman With a Left Atrial Myxoma
Authors: Wang Yuanhong , Sharkey Francis E. 
Published: January 2021

Abstract
Although atrial myxoma is the most common primary tumor of the heart, the synchronous occurrence of myxomas of the intestine and the heart has not been reported in the English literature. We report a case of a 47-year-old woman who presented with small bowel obstruction by a pedunculated mass that was found to be a myxoma after resection. A left atrial mass was found incidentally by a computed tomographic scan, and a diagnosis of atrial myxoma was confirmed after a second surgery. The cardiac myxoma showed classic histologic features, with tumor cells layered around vascular channels in an abundant myxoid matrix, while the small bowel lesion was less cellular. Immunohistochemical stains yielded identical results in both. No vascular involvement was noted at either site. This case supports the recommendation that a search for a cardiac lesion should be performed when a myxoma is identified at an unusual location.
Specimen Collection Volumes for Laboratory Tests
Authors: Dale Jane C. , Ruby Stephen G. 
Published: January 2021

Abstract
Context.—Unnecessary tests, inefficient ordering practices, and collection of more blood than is required for testing contribute to iatrogenic anemia in hospitalized patients. Laboratories accredited by the College of American Pathologists are expected to review phlebotomy practices for specimen collection volumes periodically.
Objective.—To report specimen collection, analytic, and discard volumes for routine laboratory tests and to identify practice variables associated with overcollection and blood wastage.
Design.—Clinical laboratories participating in the College of American Pathologists Q-Probes laboratory improvement program recorded collection container size, laboratory-defined requested volume, manufacturer-defined analytic volume, and average discard volume for routine complete blood cell counts and electrolyte panels ordered for patients in intensive care units. Participants provided information about their specimen collection, processing, and analytic practices in a questionnaire.
Setting and Participants.—A total of 140 public and private institutions.
Main Outcome Measures.—Overcollections for routine collections and for situations in which a reduced volume of specimen is collected, and average discard volume per tube.
Results.—Laboratories collected a median of 2.76 mL (or 8.5 times) more than their instrument's analytic volume for routine complete blood cell counts and 1.75 mL (or 12 times) more than their instrument's analytic volume for routine electrolyte panels. For clinical situations in which reduced collection volumes were necessary, overcollection for the same analytes was 0.5 mL (3 times) and 0.44 mL (4.2 times), respectively. The median discard volume was 2.8 mL/tube for complete blood cell counts and 2.0 mL/tube for electrolyte panels. Specimen collection container size was directly associated with overcollections and discard volumes. Instrument analytic volume was not a determinant of blood wastage.
Conclusions.—Most laboratories can decrease collection volumes without compromising the ability of the laboratory to report a reliable and timely result. Use of smaller collection tubes can help reduce blood wastage.
Results of the Survey of the Quality Assurance for Commercially Prepared Microbiology Media
Authors: Jones Ronald N. , Krisher Karen , Bird Deborah S. 
Published: January 2021

Abstract
Context.—Beginning in 1985, state-of-the-art surveys by the College of American Pathologists (CAP) led to M22-A guidelines by the National Committee for Clinical Laboratory Standards (NCCLS) for quality assurance (QA) of various commercially prepared isolation and diagnostic microbiology media. Some medium types were declared exempt from routine QA testing by each laboratory user, but manufacturer QA was maintained and specified in great detail. No update has occurred in more than 15 years as more complex media have been introduced into clinical microbiology practice.
Objective.—To reassess the quality of commercially prepared microbiology media in the United States for the revision of NCCLS document M22-A2.
Methods.—A questionnaire was designed to conform to that used by the CAP in 1985 and 1988, and was updated by lists of 52 recently introduced diagnostic media. Queries included details of laboratory QA in the last 12 months, such as number of lots tested, number of items in a lot, number of items in a quality control (QC) sample, number of lots failed, and reasons for lot failure. All CAP Microbiology Surveys participants received the document in late 2001.
Results.—Data from nearly 300 000 media lots representing 32.7 million medium items were received from more than 3000 CAP Surveys subscribers. Lot raw data failure rates for all media ranged from 0.10% to 9.87% (average, 1.01%). Failures with media having a significant QC experience (≥1000 lots or ≥100 000 items) adjusted for QC strain-based failures (so-called extrapolated failure rate) ranged from 0.04% to 1.34% (average, 0.40%). The threshold rate for QA exemption from 1985 analyses was expanded to 0.50% or less and now allows exemption of 27 media evaluated in this study. Local laboratory QA must remain in force (M22-A2) for the other 25 products.
Conclusions.—Generated QA failure results from the CAP Microbiology Surveys supplement recent results of the NCCLS M22 Subcommittee that will lead to more practical media QA guidelines and could significantly decrease costs for clinical microbiology laboratories through focusing QC on a smaller number of the most at-risk diagnostic products.
Colorectal Carcinoma Nodal Staging
Authors: Turner Roderick R. , Nora Dean T. , Trocha Steven D. , Bilchik Anton J. 
Published: January 2021

AbstractContext.—Nodal staging accuracy is important for prognosis and selection of patients for chemotherapy. Sentinel lymph node (SLN) mapping improves staging accuracy in breast cancer and melanoma and is being investigated for colorectal carcinoma.Objective.—To assess pathologic aspects of SLN staging for colon cancer.Design.—Sentinel lymph nodes were identified with a dual surgeon-pathologist technique in 51 colorectal carcinomas and 12 adenomas. The frequency of cytokeratin (CK)–positive cells in mesenteric lymph nodes, both SLN and non-SLN, was determined along with their immunohistochemical characteristics.Results.—The median number of SLNs was 3; the median number of total nodes was 14. The CK-positive cell clusters were detected in the SLNs of 10 (29%) of 34 SLN-negative patients. Adjusted per patient, SLNs were significantly more likely to contain CK-positive cells than non-SLNs (P &lt; .001). Cell clusters, cytologic atypia, and/or coexpression of tumor and epithelial markers p53 and E-cadherin were supportive of carcinoma cells. Single CK-positive cells only, however, could not be definitively characterized as isolated tumor cells; these cells generally lacked malignant cytologic features and coexpression of tumor and epithelial markers and in 2 cases represented mesothelial cells with calretinin immunoreactivity. Colorectal adenomas were associated with a rare SLN CK-positive cell in 1 (8%) of 12 cases.Conclusions.—Sentinel lymph node staging with CK-immunohistochemical analysis for colorectal carcinomas is highly sensitive for detection of nodal tumor cells. Cohesive cell clusters can be reliably reported as isolated tumor cells. Single CK-positive cells should be interpreted with caution, because they may occasionally represent benign epithelial or mesothelial cells.
Comparison of Voice-Automated Transcription and Human Transcription in Generating Pathology Reports
Authors: Al-Aynati Maamoun M. , Chorneyko Katherine A. 
Published: January 2021

Abstract
Context.—Software that can convert spoken words into written text has been available since the early 1980s. Early continuous speech systems were developed in 1994, with the latest commercially available editions having a claimed accuracy of up to 98% of speech recognition at natural speech rates.
Objectives.—To evaluate the efficacy of one commercially available voice-recognition software system with pathology vocabulary in generating pathology reports and to compare this with human transcription. To draw cost analysis conclusions regarding human versus computer-based transcription.
Design.—Two hundred six routine pathology reports from the surgical pathology material handled at St Joseph's Healthcare, Hamilton, Ontario, were generated simultaneously using computer-based transcription and human transcription. The following hardware and software were used: a desktop 450-MHz Intel Pentium III processor with 192 MB of RAM, a speech-quality sound card (Sound Blaster), noise-canceling headset microphone, and IBM ViaVoice Pro version 8 with pathology vocabulary support (Voice Automated, Huntington Beach, Calif). The cost of the hardware and software used was approximately Can $2250.
Results.—A total of 23 458 words were transcribed using both methods with a mean of 114 words per report. The mean accuracy rate was 93.6% (range, 87.4%–96%) using the computer software, compared to a mean accuracy of 99.6% (range, 99.4%–99.8%) for human transcription (P &lt; .001). Time needed to edit documents by the primary evaluator (M.A.) using the computer was on average twice that needed for editing the documents produced by human transcriptionists (range, 1.4–3.5 times). The extra time needed to edit documents was 67 minutes per week (13 minutes per day).
Conclusions.—Computer-based continuous speech-recognition systems in pathology can be successfully used in pathology practice even during the handling of gross pathology specimens. The relatively low accuracy rate of this voice-recognition software with resultant increased editing burden on pathologists may not encourage its application on a wide scale in pathology departments with sufficient human transcription services, despite significant potential financial savings. However, computer-based transcription represents an attractive and relatively inexpensive alternative to human transcription in departments where there is a shortage of transcription services, and will no doubt become more commonly used in pathology departments in the future.
Multifocal Subcutaneous Phaeohyphomycosis Caused byPhialophora verrucosa
Authors: Kimura Masatomo , Goto Akio , Furuta Tomoko , Satou Takao , Hashimoto Shigeo , Nishimura Kazuko 
Published: January 2021

AbstractAn otherwise healthy 85-year-old woman presented with purulent multifocal subcutaneous nodules on the dorsal side of the right forearm and hand. Histopathologic examination of the biopsied specimen showed a subcutaneous granuloma with central abscess and necrosis, consistent with phaeomycotic cyst. Faint brown septate hyphae and moniliform fungal elements were found in the granuloma. Culture of the discharge grew Phialophora verrucosa. This fungus has rarely been reported as a pathogen of subcutaneous phaeohyphomycosis. Subcutaneous phaeohyphomycosis usually presents as a single lesion. In this case of multifocal lesions, initial imperfect excision seems to have caused satellite lesions. To our knowledge, this is the first report of multifocal subcutaneous phaeohyphomycosis caused by P verrucosa. The disease responded to oral itraconazole administration.
Metastatic Infiltrating Syringomatous Adenoma of the Breast
Authors: Chang C. K. , Jacobs Ira A. , Calilao Gabriel , Salti George I. 
Published: January 2021

Abstract
Infiltrating syringomatous adenoma of the breast is classified as a benign, locally invasive neoplasm. To our knowledge, there have been no reported cases of metastasizing syringomatous adenomas. We used sentinel lymph node mapping to identify metastatic cells, leading to a diagnosis of infiltrating syringomatous adenoma of the breast.
EDUCANDO PARA PARTO ATIVO POR VIA REMOTA: uma realidade no contexto da PANDEMIA.
Authors: APL Amanda Paganini Lourencini 
Published: January 2021

Na década de 70 houve um movimento pela autonomia feminina no parto, para que o ato de parir fosse algo natural e guiado pela mulher/mãe. O Grupo PEMEDUTS/UFMT com o objetivo de socializar saberes e fazeres, realizou oficina voltada para área saúde, com o tema “Parto Ativo Multiprofissional” com expertise no tema. Este estudo é de abordagem qualitativa, sobre ação de extensão com elaboração de e-book. que possibilitou participação ativa e consolidação do saber. A pandemia e o isolamento social devem servir de incentivos para a utilização da extensão como educação em saúde, contribuindo para as mudanças no cenário e do olhar sobre o protagonismo feminino na parição, com a mudança da práxis.
Effects of coconut water on blood sugar and retina of rats with diabetes
Authors: Dai Yanan , Peng Li , Zhang Xiaohua , Wu Qingjing , Yao Jie , Xing Qiu , Zheng Yunyan , Huang Xiaobo , Chen Shaomei , Xie Qing 
Published: January 2021

Background
This study aimed to evaluate the effects of coconut water on the general condition (fasting blood sugar and body weight) and retina of diabetic rats.

Methods
Forty-eight Sprague–Dawley male rats were divided into normal controls (NC), diabetes mellitus (DM), diabetes+coconut water (DM+CW), and diabetes+glibenclamide (DM+Gli) groups. After 4 weeks of normal feeding, coconut water was given to group III-DM+CW and 0.6 mg/kg glibenclamide to group IV–DM+Gli. The blood sugar, body weight, total retinal thickness, pathological changes, and VEGF expression in the retina were analyzed at different time points.

Results
The fasting blood sugar was 4–6 mmol/L in group I-NC and continuously increased in group II-DM, whereas gradually decreased after the 4th experiment week in the remaining two groups. The rats, except in group I-NC, have lost weight. In group II-DM, the total retinal thickness was significantly increased after the 8th and 12th experiment week, and the pathological changes in retina were observed. VEGF was almost fully expressed in the ganglion cell layer and inner granular layer and partially expressed in the outer granular layer in group II-DM, and mainly expressed in the ganglion cell layer and inner layer in group I-NC, with a lighter color. Group III-DM + CW and group IV-DM + Gli demonstrated similar VEGF expression as in group I-NC.

Conclusions
Coconut water has the potential to reduce blood sugar and diabetic retinal damage, serving as a candidate drug or nutrient for treating diabetes and its complications.
The interconnection between entrepreneurship and dynamic capabilities: a bibliometric analysis
Authors: Cruzara Giovani , Kaniak Vivien Mariane Massaneiro , Caciatori Junior Itamir , Teixeira Rivanda Meira 
Published: January 2021

This study uses a bibliometric approach to analyze how the scientific production of entrepreneurship and the theoretical approach of the dynamic capabilities is corelated. With a sample of 701 studies from the Web of Science database we identified 88 articles concentrated in four different journals, pointing the most productive authors, the most cited references and clusters of keywords mainly related to entrepreneurship and dynamic capabilities. The results demonstrates that entrepreneurship and dynamic capabilities are two research streams that still need to have their relationships better explored, since the bibliometric maps demonstrated that most studies appear to have a main focus on dynamic capabilities but only addressing entrepreneurship related either to the entrepreneur itself, or to its entrepreneurial orientation, not exploring other important entrepreneurship issues. This work contributes theoretically by addressing a relationship still underexplored at the academy, thus encouraging future studies on the theme.
Eosinophilic Granulomatosis with Polyangiitis: A Systematic Review and Meta‐Analysis of Test Accuracy and Benefits and Harms of Common Treatments
Authors: Springer Jason M. , Kalot Mohamad A. , Husainat Nedaa M. , Byram Kevin W. , Dua Anisha B. , James Karen E. , Chang Lin Yih , Turgunbaev Marat , Villa‐Forte Alexandra , Abril Andy , Langford Carol A. , Maz Mehrdad , Chung Sharon A. , Mustafa Reem A. 
Published: January 2021

ObjectiveEosinophilic granulomatosis with polyangiitis (EGPA) is part of a group of vasculitides commonly referred to as antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV), in addition to granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and renal‐limited vasculitis. Patients with EGPA characteristically have asthma and marked peripheral eosinophilia with only approximately 30% to 35% of patients being myeloperoxidase (MPO)‐ANCA positive, distinguishing it from other forms of AAV (1,2). The aim of this systematic review is to support the development of the American College of Rheumatology/Vasculitis Foundation guideline for the management of EGPA.MethodsA systematic review was conducted of the literature for seven forms of primary systemic vasculitis (GPA, MPA, EGPA, polyarteritis nodosa, Kawasaki disease, giant cell arteritis, and Takayasu arteritis). The search was done for articles in English using Ovid Medline, PubMed, Embase, and the Cochrane Library. Articles were screened for suitability in addressing population/patients, intervention, comparator, and outcomes (PICO) questions, with studies presenting the highest level of evidence given preference. Two independent reviewers conducted a title/abstract screen and full‐text review for each eligible study.ResultsThe initial search, conducted in August 2019, included 13 800 articles, of which 2596 full‐text articles were reviewed. There were 190 articles (addressing 34 PICO questions) reporting on the diagnosis and management of EGPA.ConclusionThis comprehensive systematic review synthesizes and evaluates the accuracy of commonly used tests for EGPA as well as benefits and toxicities of different treatment options.
Anion Constructor for Atomic‐Scale Engineering of Antiperovskite Crystals for Electrochemical Reactions
Authors: Lee Sehyun , Jung Jae Young , Jang Injoon , Choi Daeil , Lee Myeong Jae , Lee Dong Wook , Jang Jue‐Hyuk , Lee Jeong Hee , Jin Haneul , Im Kyungmin , Lee Eungjun , Kim Seung‐hoon , Kim Nam Dong , Lee Soo‐Hyoung , Kang Yun Sik , Park Hee‐Young , Chun Dongwon , Ham Hyung Chul , Lee Kug‐Seung , Ahn Docheon , Kim Pil , Yoo Sung Jong 
Published: January 2021

AbstractAmong the Pt group metals, Pd has been considered the most efficient for application in electrocatalysts as an alternative to Pt. Despite the comparable electrochemical activities of Pd and Pd‐metal alloys, they are vulnerable to liquid acidic electrolytes, leading to degradation of catalytic activity. Pd–Ni alloys have been used to enhance catalytic activity because the electronic structure of Pd can be easily changed by adding Ni. In other studies, N atoms have been introduced for more stable M–Ni catalysts by inducing the formation of Ni4N species; however, the structural analysis and the role of nitrogen have not been fully understood yet. Herein, the Pd–Ni alloy nitride with a unique crystal structure shows a promising catalytic activity for oxygen reduction reaction (ORR). The nitride PdNi nanoparticles have a novel monolithic antiperovskite structure of chemical formula (PdxNi1−x)NNi3. The unique antiperovskite crystal (PdxNi1−x)NNi3 possesses superior ORR activity and stability, originating from the downshifted d‐band center of the monolayer Pd/antiperovskite surface and the lower formation energy of the antiperovskite core nanocrystal. Consequently, (PdxNi1−x)NNi3, as a Pt‐free Pd‐based electrocatalyst, overcomes the stability issue of Pd under acidic conditions by achieving 99‐times higher mass activity than commercial Pd/C, as shown by the durability test.
Side‐Chain Engineering for High‐Performance Conjugated Polymer Batteries
Authors: Li Xiaoyi , Li Yilin , Sarang Kasturi , Lutkenhaus Jodie , Verduzco Rafael 
Published: January 2021

AbstractConjugated polymers are attractive for energy storage but typically require significant amounts of conductive additives to successfully operate with thin electrodes. Here, side‐chain engineering is used to improve the electrochemical performance of conjugated polymer electrodes. Naphthalene dicarboximide (NDI)‐based conjugated polymers with ion‐conducting ethylene glycol (EG) side chains (PNDI‐T2EG) and non‐ion‐conducting 2‐octyldodecyl side chains (PNDI‐T2) are synthesized, tested, and compared. For thick (20 µm, 1.28 mg cm−2) electrodes with a 60 wt% polymer, the PNDI‐T2EG electrodes exhibit 66% of the theoretical capacity at an ultrafast charge–discharge rate of 100C (72 s per cycle), while the PNDI‐T2 electrodes exhibit only 23% of the theoretical capacity. Electrochemical impedance spectroscopy measurements on thin (5 µm, 0.32 mg cm−2), high‐polymer‐content (80 wt%) electrodes reveal that PNDI‐T2EG exhibits much higher lithium‐ion diffusivity (DLi+ = 7.01 × 10−12 cm2 s−1) than PNDI‐T2 (DLi+ = 3.96 × 10−12 cm2 s−1). PNDI‐T2EG outperforms most previously reported materials in thick, high‐polymer‐content electrodes in terms of rate performance. The results demonstrate that the rate performance and capacity are significantly improved through the incorporation of EG side chains, and this work demonstrates a route for increasing the rate of ion transport in conjugated polymers and improving the performance and capacity of conjugated‐polymer‐based electrodes.
Constructing Li‐Rich Artificial SEI Layer in Alloy–Polymer Composite Electrolyte to Achieve High Ionic Conductivity for All‐Solid‐State Lithium Metal Batteries
Authors: Liu Yuxuan , Hu Renzong , Zhang Dechao , Liu Jiangwen , Liu Fang , Cui Jie , Lin Zuopeng , Wu Jinsong , Zhu Min 
Published: January 2021

AbstractTo achieve high ionic conductivity for solid electrolyte, an artificial Li‐rich interface layer of about 60 nm thick has been constructed in polymer‐based poly(ethylene oxide)‐lithium bis(trifluoromethanesulfonyl)imide composite solid electrolyte (briefly noted as PEOm) by adding Li‐based alloys. As revealed by high‐resolution transmission electron microscopy and electron energy loss spectroscopy, an artificial interface layer of amorphous feature is created around the Li‐based alloy particles with the gradient distribution of Li across it. Electrochemical analysis and theoretical modeling demonstrate that the interface layer provides fast ion transport path and plays a key role in achieving high and stable ionic conductivity for PEOm‐Li21Si5 composite solid electrolyte. The PEOm‐5%Li21Si5 composite electrolyte exhibits an ionic conductivity of 3.9 × 10–5 S cm−1 at 30 °C and 5.6 × 10−4 S cm−1 at 45 °C. The LiFePO4 | PEOm‐5%Li21Si5 | Li all‐solid‐state batteries could maintain a stable capacity of 129.2 mA h g−1 at 0.2 C and 30 °C after 100 cycles, and 111.3 mA h g−1 after 200 cycles at 0.5 C and 45 °C, demonstrating excellent cycling stability and high‐rate capability.