bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uso de aspirina para prevención de preeclampsia
Authors: Villegas Chavarría Dayanna , Cordero Espinoza Fabiola 
Published: October 2021

La preeclampsia es una enfermedad multisistémica que puede traer repercusiones tanto en la madre como en feto, hasta el día de hoy el único tratamiento recomendado es la inducción del parto, es por esto que es importante buscar alternativas en cuanto al manejo, se ha observado un beneficio con el uso de aspirina en dosis bajas en mujeres de alto riesgo de desarrollar preeclampsia. La prevención de las secuelas asociadas, como el parto prematuro y el RCIU en el feto, o disfunción multiorgánica en la madre, se puede lograr al iniciar aspirina como profilaxis en <16 semanas de gestación.
ANALISIS INDEKS GLIKEMIK DAN KANDUNGAN GIZI SAGU PORNO
Authors: Pramardika Dhitodwi , Gansalangi Ferdinand 
Published: October 2021

Di Kabupaten Sangihe terdapat satu pangan lokal yang terkenal yaitu bernama “Sagu Porno”. Panganan khas asli dari suku Sangihe yang terbuat dari tanaman sagu yang diolah dengan cara dibakar. Masyarakat sangihe memepercayai bahwa makanan ini bagus jika dikonsumsi penderita diabetes. Namun penelitian ilmiah mengenai pangan tersebut masih sangat minim. Berdasarkan hal tersebut, penelitian ini dilakukan dengan tujuan untuk menganalisis indeks glikemik dan kandungan gizi pada Sagu Porno. Penelitian ini merupakan penelitian eksperimen. Lokasi pengujian kandungan gizi dilaksanakan di Laboratorium Balai Riset dan Standarisasi Industri Kota Manado sedangkan untuk pengukuran indeks glikemik dilakukan di Politeknik Negeri Nusa Utara. Subjek pada penelitian ini sebanyak 14 responden dan objek pada penelitian ini adalah sagu porno. Berdasarkan hasil uji kandungan gizinya, sagu porno memiliki kandungan karbohidrat sebanyak 50,65%, protein 2,06%, lemak 11,75% dan serat kasar 3,12%. Berdasarkan hasil uji kandungan indeks glikemiknya diketahui bahwa sagu porno adalah 296,53% yang artinya bahwa sagu porno merupakan panganan dengan indeks glikemik tinggi. Kesimpulannya, tidak disarankan penderita diabetes untuk mengkonsumsi panganan sagu porno.

in Sangihe District, famous food as a local food called “Sagu Porno”. Secialty original dish from Sangihe tribe, which it was made from the sago plant with burned processed. The people very much believe that those food was good if consumed by diabetics. However, scientific quantity research on those foods were little. Based on those study the aim of analyzing were the glycemic index and nutritional content of Sagu Porno. Those research was an experimental research. The location for testing the nutritional content was on the laboratory Balai Riset dan Standarisasi Industri of Manado City, while for the measurement of the glycemic index at Politeknik Negeri Nusa Utara. The subjects in those study were 14 respondents and the object in those study was Sagu Porno. Based on the results of the nutritional content test, Sagu Porno has a carbohidrate content of 50.65%, 2.06% protein, 11.75% fat, and 3.12% crude fiber. Based on the results of the glycemic index content test, it was known that Sagu Porno was 296.53%, which means that Sagu Porno is a food with a high glycemic index. In conclusion, diabetics are not advised to consume Sagu Porno.
PERILAKU HIDUP BERSIH SEHAT TATANAN RUMAH TANGGA DI DAERAH KEPULAUAN
Authors: Patras Mareike D. , Tinungki Yeanneke L. 
Published: October 2021

Perilaku Hidup Bersih dan Sehat (PHBS) merupakan cerminan pola hidup keluarga yang senantiasa memperhatikan dan menjaga kesehatan seluruh anggota keluarga. Semua perilaku kesehatan yang dilakukan atas kesadaran sehingga keluarga atau anggota keluarga dapat menolong dirinya sendiri dibidang kesehatan dan dapat berperan aktif dalam kegiatan-kegiatan dibidang kesehatan di masyarakat. Hal ini terjadi karena kurangnya perilaku hidup bersih sehat keluarga. Guna mencegah penyakit menular dan tidak menular, setiap anggota rumah tangga perlu diberdayakan,dalam melaksanakan 10 (sepuluh) indikator PHBS Pelaksanaan PHBS Kabupaten Sangihe tahun 2017 50,40%. Di Kecamatan Tabukan Selatan Tengah 280 KK Keluarga yang di pantau ,yang ber PHBS 114 (40,2%). Tujuan penelitian ingin mengetahui Hubungan Pengetahuan dan Sikap Keluarga dengan Perilaku Hidup Bersih Sehat. Metode penelitian dengan menggunakan rancangan Cross sectional study. Hasil penelitian tidak ada hubungan pengetahuan dengan penerapan Perilaku hidup Bersih Sehat diperoleh nilai P yaitu = 0,171 >ᾳ 0,05 dan ada hubungan antara sikap dengan penerapan Perilaku hidup Bersih Sehat nilai p value 0,03 < ᾳ (0.05). Disarankan agar setiap anggota keluarga termotivasi melaksanakan 10 indikator PHBS

Clean and Healty living behavior showed of fammily pattern live style in order to prevent infectious and non-communicable diseases, every member of the household needs to be empowered in implementing 10 (ten) indicators of Clean and Healthy Living Behavior. In 2017 the implementation in Sangihe District was 50.40%. The family monitored in Tabukan Selatan Tengah Subdistrict were 280 families, apply clean and healthy living behavior about 114 (40.2%). Method of those reaseach apply cross sectional study, design and the result of the research show that was not a relationship between knowledge and clean healthy life behavior with p value 0.016 <ᾳ (0.05) and those was a relationship between attitude and clean healthy lifestyle, p value 0.03 <ᾳ (0.05). The member of fammily incentive to motivate ten (10) standards of Clean Healty living behavior.
PENGARUH PAKAN MENGANDUNG BAKASANG DALAM MENINGKATKAN PERTUMBUHAN DAN KELANGSUNGAN HIDUP IKAN BAWAL (Colossoma macropomum)
Authors: Manurung Usy Nora , Langi Edwin Oscar 
Published: October 2021

Bakasang, produk fermentasi dari jeroan ikan, mengandung Bakteri Asam Laktat (BAL) yang beberapa diantaranya tergolong bakteri probiotik yang dapat meningkatkan pertumbuhan ikan. Penelitian ini bertujuan untuk mengkaji pengaruh pakan mengandung bakasang (PMB) terhadap pertumbuhan dan kelangsungan hidup ikan bawal (Colosoma macropomum) dan menentukan dosis paling efektif dari bakasang terhadap pertumbuhan dan kelangsungan hidup ikan bawal. Sebanyak 120 ekor ikan yang ditempatkan dalam 12 hapa dengan kepadatan 10 ekor ikan/hapa. Setelah proses aklimatisasi, ikan uji diberi PMB dengan empat dosis berbeda (A=0 ml/kg pakan, B= 50 ml/kg pakan, C=75 ml/kg pakan dan D=100 ml/kg pakan) dengan tiga ulangan pada masing-masing perlakuan, pada dosis 5%/bb/hari, diberikan dua kali sehari selama 14 hari. Hasil penelitian menunjukan bahwa pengaruh pemberian pakan meningkat bertambahnya konsentrasi dengan pertumbuhan terbaik teramati pada dosis 100 ml/kg pakan dengan bertumbuhan sebesar 8.7 gram. Hasil ini memperlihatkan bahwa bakasang merupakan sumber potential probiotik yang dapat meningkatkan pertumbuhan ikan bawal meskipun pengujian dengan periode pemeliharaan lebih lama perlu dilakukan untuk melihat pengaruh optimum dari PMB terhadap pertumbuhan dan kelangsungan hidup.

Bakasang, a fermentation product made from fish’s viscera, contains Lactic Acid Bacteria (LAB), some of which are probiotic bacteria that can increase fish growth. This study aimed to determine effect of fish feed containing bakasang (FCB) and the effective dose of bakasang on the growth of pomfret (Colosoma macropomum). 120 fish were placed in small net cage (1x1x1) m3. Following acclimatization process, the test fish were fed with four different doses of FCB (A = 0 ml/kg of feed, B = 50 ml/kg of feed, C = 75 ml/kg of feed and D = 100 ml/kg of feed) at a dose of 5% /w/day twice a day in triplicate for 14 days. The results showed that the effect of FCB on the pamfret fish growth increased in a dose dependent manner with best growth observed at a dose of 100 ml/kg of feed with growth of 8.7 gram, suggesting bakasang as potential source of probiotic that can increase the growth of pamfret fish although further study covering longer period time is required to measure the optimum potential of FCB on pamfret fish growth and survival rate.
PENGARUH RADIASI SINAR ULTRAVIOLET TIPE C (UVC) TERHADAP KULTUR TOTAL MIKROBA IKAN ASAP PINEKUHE
Authors: Palawe Jaka Frianto Putra , Mandeno Jefri 
Published: October 2021

Untuk meningkatkan mutu produk olahan khas daerah, khususnya ikan asap pinekuhe, pengembangan teknik atau instrumen baru menjadi sebuah keharusan. Sejauh ini, metode yang umum digunakan untuk mempertahankan mutu produk pangan, khususnya mutu mikrobiologis, adalah mensterilkan produk pangan untuk mengurangi dan menginaktifkan mikroba kontaminan misalnya melalui perebusan, penggaraman atau pengasapan. Tetapi metode steriliasi menggunakan sinar ultraviolet khususnya tipe C (UVC) belum banyak diterapkan pada produk pangan di Indonesia. Sinar ultraviolet adalah gelombang elektromagnetik yang memiliki muatan elektron berfrekuensi tinggi dan panjang gelombang 100-400 nm. Sinar UV dapat memotong rantai basa nitrogen dalam RNA atau DNA sehingga menyebabkan kegagalan pemberian kode genetik untuk sintesa protein dan kematian mikroba. Penelitian ini bertujuan untuk mempelajari pengaruh sinar UVC terhadap isolat kultur mikroba dari ikan asap pinekuhe dengan menggunakan metode observasi dan analisa data secara deskriptif. Koloni bakteri yang diisolasi dari ikan pinekuhe dipaparkan dengan sinar UVC dengan perlakuan (12, 24, 36 dan 48) jam. Hasil penelitian menunjukan bahwa sinar ultra violet tipe c (UVC) dengan daya 8 va dan penyinaran 48 jam mempengaruhi pertumbuhan koloni mikroba ikan asap pinekuhe secara maksimal berupa kekeringan pada koloni bakteri isolat dari ikan asap pinekuhe.

To improve quality of pinekuhe smoked fish locally produced in Sangihe Islands, development of new techniques or instruments becomes necessary. Widely used techniques for maintaining food quality mainly include sterilization through boiling, salting or smoking. To date, however, sterilization by ultraviolet type C (UVC) has been poorly practiced for preserving food products in Indonesia. Ultraviolet light is an electromagnetic wave that has a high frequency electron charge with a wavelength of 100-400 nm. It can cut the nitrogenous base chains in RNA or DNA resulting in coding failure in protein synthesis, causing the death of microbes. This research aimed to study the effect of UVC on microbes isolated from pinekuhe. The results showed that UVC radiation with 8 va for 48 hours significantly affected the growth of microbial colonies isolated from the smoked fish, drying up the bacterial colony.
PENGARUH PERENDAMAN DAN DURASINYA DALAM LARUTAN MADU TERHADAP MASKULINASASI LARVA Oreochromis niloticus
Authors: Tomasoa Aprelia , Azhari Deidy , Manansang Christian Andelsen , Dansole Ferly Feybe 
Published: October 2021

Budidaya ikan nila monoseks jantan memiliki peranan penting dalam meningkatkan produksi ikan nila. Meskipun saat ini teknik maskulinisasi menggunakan hormon sintetik umum diterapkan namun cara ini berbahaya dari segi keamanan pangan dan konsumen karena sifat karsinogenik dan potensi akumulasi di alam dari hormon sintetik. Sebaliknya, bahan alami seperti madu yang menggandung Chrysin, yang telah diketahui sebagai aromatase inhibitor yang dapat menyebabkan maskulinisasi pada ikan dapat digunakan dalam teknik maskulinisasi. Meskipun demikian, sejauh ini pengaruh perendaman larva ikan nila dalam larutan madu terhadap maskulinisasi masih harus dikaji. Penelitian ini bertujuan untuk mengetahui pengaruh perendaman dan durasi perendaman dalam larutan madu terhadap rasio kelamin jantan benih ikan nila. Menggunakan larva berumur 7 hari hasil pemijahan semi-buatan dengan induksi hormon, penelitian ini dilakukan menggunakan 4 perlakuan (durasi perendaman) dengan 1 konsentrasi (15 mL/L). Untuk mengetahui rasio kelamin jantan, analisa histologis dengan pewarnaan asetokarin dilakukan untuk mengamati gonad benih hasil perlakuan. Perendaman larva ikan nila pada larutan madu konsentrasi 15 mL/L selama 20 jam mampu menghasilkan 80% benih berkelamin jantan. Sebagai kesimpulan, durasi perendaman berpengaruh terhadap rasio kelamin jantan yang dihasilkan dan perendaman selama 20 jam adalah durasi perendaman terbaik untuk larva ikan nila.

Farming monosex male tilapia has an important role in improving the production of Nile tilapia. Although synthetic hormone is commonly used to produce male monosex tilapia, this method poses a serious threat to food safety and consumer’s health due to carcinogenic potential and bioaccumulation of the synthetic hormone in ecosystem. In contrast, honeybee is a natural product containing Chrysin, an aromatase inhibitor, which is known to cause masculinity in fish and can be used for masculinization. To date, however, the effect of honeybee on tilapia larvae’s masculinization is yet to be studied. This research aimed to study the effect of immersion and its duration in honeybee’of Nile Tilapia’s Larvae in honeybee’s solution and length of immersion on male ratio. This research was conducted in quadruple consisting of three different times of immersion (duration of immersion) and one concentration (15 mL/L). Using 7-day post hatched Nile tilapia larvae from semi-artificial breeding, we determined male ratio based on histological analysis using acetocarmine stain. The result show that the Nile Tilapia’s larvae treated at the concentration of 15 mL/L of honeybee for 20 hours had the highest male ratio (80%). To conclude, immersion in honeybee solution affected male ratio with 20 hours length of immersion resulting in the highest male ratio for tilapia’s larvae.
Coexistent intracranial midline cysts: Persistent cavum septum pellucidum, cavum vergae, cavum velum interpositum, and a pineal cyst
Authors: TIRYAKIOGLU Mehtap 
Published: October 2021

This case is presented after a concurrent cavum septum pellucidum, cavum vergae, cavum velum interpositum, and a pineal cyst
prevailed following a magnetic resonance imaging evaluation for a temporary blindness the patient reported that she recently had.
Heterosis and Combining Abilities Studies in Okra [Abelmoschus esculentus (L.) Moench]
Authors: Nanthakumar S. , Kuralarasu C. , Gopikrishnan A. 
Published: October 2021

Aim: Genetically complementary parents and amount of heritability of economic traits determines the successful development of breeding population, hybrids and varieties. The studies on heterosis and combining ability are useful in formulating effective breeding strategies and selection of suitable parents for crosses in breeding program.
Study Design: During the study period24 F1hybrids and their 10 parents were evaluated along with commercial check (‘Shakthi’) in a randomized block design (RBD) with three replication.
Place and Duration of the Study: The present study was conducted at Adhiparasakthi Agricultural College farm, Kalavai, Vellore district of Tamil Nadu state during summer 2014.
Methodology: The experimental material consist of 24 F1 hybrids developed from six lines (EC755648, EC755653, EC 755654, IC52303, IC755652 IC111515 ) and three tester (Arakka Anamika, Parbhani, Pusa Sawani VRO 22 ). These were evaluated along with commercial check (‘Shakthi’) in a randomized block design with three replication. The observation were recorded for 14 yield and yield contributing characters.
Results: The results inferred that the predominance of non-additive gene action was observed for all the traits. Among the parents, the overall study of gca effects suggested that parent EC 755648 and Parbhanikranti were significant general combiner for yield, these can be used to improve hybrids with desirable traits in future. Significant positive SCA effects were found for all the studied traits.
Conclusion: Among the hybrids, EC755653 x ArakkaAnamikaand IC111515 x ParbhaniKrantishowed desirable standard heterosis percentage over the check Shakthi along with good sca effects and per se performance for yield and other important yield contributing traits, thus it can be effectively be exploited in hybrid breeding programme.
Pharmacognostic Specifications of Calotropis procera (Aiton) W. T. Aiton Leaf and Tribulus terrestris L. Fruit: Important Medicinal Plants Used in Veterinary Products
Authors: Monika . , Akanksha . , Lal Snigdha 
Published: October 2021

Present article deals with the pharmacognostic specification of selected medicinal plants used in veterinary products for the purpose of their standardization, as evidential support concerning quality determination of plant material in veterinary medicine is scarce and there is poor documentation on primary studies of many species. The plants undertaken for the study were Calotropis procera (Apocynaceae) and Tribulus terresteris (Zygophyllaceae) on the basis of their usage relevance in veterinary products. Both plants are official in Ayurvedic Pharmacopoeia of India. Morphology as well as various pharmacognostic aspects of different parts of the plant were studied and have been described, which will help in authentication and quality control. The observed microscopic characters of Calotropis procera leaf were rubiaceous type apostomatic stomata, epidermis, collenchymas, parenchyma, vascular bundles, palisade cells, cortical fibres and lamina, trichomes on the cuticle of lamina. Microscopic characteristics of Tribulus terrestris fruit were epicarp cells showing clusters of calcium oxalate crystals, xylem vessels, group of thin walled sclerenchymatous fibres, group of stone cells of mesocarp. Powder microscopy of the Tribulus terrestris fruit shows abundance of epidermal trichomes - simple, short, long, thick walled, multicellular covered trichomes, sclereids. The qualitative microscopic features would prove useful for laying down their pharmacopoeial standards. The present study also provides the information with respect to identification and authentication of crude drug and serves as a reference point for the proper identification of Calotropis procera leaf and Tribulus terrestris fruit, thereby contributing to the scientific world of research.
Corpos que desafiam as normas: narrativas da Defensoria Pública sobre intersexualidade
Authors: De Oliveira Manoel Rufino David , Gonçalves Alisson Costa 
Published: October 2021

os corpos intersexuais, por borrarem as fronteiras de sexo, gênero e sexualidade, e confrontarem a matriz heterossexual estabelecida pela sociedade patriarcal, situam-se numa longa e infindável rede de relações de poder. Por estar no campo do Direito e da Medicina, essa rede é ora coercitiva e negativa, ora produtiva e positiva. Dessa forma, o presente trabalho busca analisar como o Núcleo de Direitos Humanos da Defensoria Pública do Estado do Pará atua nas demandas jurídicas de pessoas intersexuais, a partir de entrevista semiestruturada com a Defensora Pública Anelyse Freitas. Para tanto, em primeiro lugar, será discutida a intersexualidade enquanto forma de vida “potencialmente perigosa” para a matriz heterossexual. Em segundo lugar, serão analisadas as demandas jurídicas de pessoas intersexuais existentes no Núcleo de Direitos Humanos da Defensoria Pública do Estado do Pará. Por fim, serão discutidos os desafios e avanços na proteção e garantia dos direitos das pessoas intersexuais. A partir da pesquisa, concluiu-se que a Medicina e o Direito são dois grandes campos de normalização dos indivíduos intersexuais na lógica binária de gênero e, nesse contexto, a obrigação de uma definição sexual jurídica e da realização da cirurgia corretiva podem acabar se tornando violações de direitos humanos. Nesse cenário, o Núcleo de Direitos Humanos da Defensoria Pública do Estado do Pará desponta como resistência, em nome da pluralidade de sexo, gênero e sexualidade e dos direitos das pessoas intersexuais.
O corpo político de Linn da Quebrada
Authors: Da Silva João Paulo 
Published: October 2021

O artigo em comento trabalhará as categorias raça, corpo, gênero e sexualidade a partir da análise do ser político da rapper e performer Linn da Quebrada, por intermédio da análise documental de entrevistas da artista associadas a trechos de suas canções. Linn é produto musical brasileiro que adentra o cenário do funk e do rapper com canções e performances que subvertem o padrão universal de comportamento social dominante no que confere ao que se espera em ser homem e ser mulher, vez que em suas letras pensa o feminino em corpos outros (corpos trans, não siliconados, afeminados, enviadados etc). Trata-se de estudo de natureza qualitativa, com análise documental exploratória e descritiva junto a pesquisa bibliográfica. Como resultado, constatou-se que a pluralidade da artista advém como instrumento político de defesa de um feminino não esperado pela maioria dos indivíduos, dando vazão por sua voz a lutas encampadas por movimentos de mulheres e pela comunidade TLGB[1]. Judith Buttler, Michael Focault e Patricia Hill Collins são autores que complementam teoricamente o que Linn transmite em seu trabalho artístico. Palavras-chaves: gênero; corpos; Linn.[1] A alteração da sigla LGBT para TLGB no texto parte de uma política de enaltecimento dos corpos travestis, transsexuais e transgêneros, sendo reiterado a terminologia por artistas pertencentes ao T da sigla, com o intuito de ampliar a visibilidade a elas nos diálogos efetivados em prol da comunidade.
Measuring treatment response to advance precision medicine for multiple sclerosis
Authors: Calabresi Peter A. , Kappos Ludwig , Giovannoni Gavin , Plavina Tatiana , Koulinska Irene , Edwards Michael R. , Kieseier Bernd , de Moor Carl , Sotirchos Elias S. , Fisher Elizabeth , Rudick Richard A. , Sandrock Alfred 
Published: October 2021

AbstractObjectiveTo assess the independent contributions of clinical measures (relapses, Expanded Disability Status Scale [EDSS] scores, and neuroperformance measures) and nonclinical measures (new brain magnetic resonance imaging [MRI] activity and serum neurofilament light chain [sNfL] levels) for distinguishing natalizumab‐treated from placebo‐treated patients.MethodsWe conducted post hoc analyses using data from the AFFIRM trial of natalizumab for multiple sclerosis. We used multivariable regression analyses with predictors (EDSS progression, no relapse, new or enlarging MRI activity, brain atrophy, sNfL levels, and neuroperformance worsening) to identify measures that independently discriminated between treatment groups.ResultsThe multivariable model that best distinguished natalizumab from placebo was no new or enlarging T2 or gadolinium‐enhancing activity on MRI (odds ratio; 95% confidence interval: 7.2; 4.7–10.9), year 2 sNfL levels <97.5th percentile (4.1; 2.6–6.2), and no relapses in years 0–2 (2.1; 1.5–3.0). The next best‐fitting model was a two‐component model that included no MRI activity and sNfL levels <97.5th percentile at year 2. There was little difference between the three‐ and two‐component models.InterpretationNonclinical measures (new MRI activity and sNfL levels) discriminate between treatment and placebo groups similarly to or better than clinical outcomes composites and have implications for patient monitoring.