bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of myeloperoxidase as a diagnostic and prognostic factor in cardiovascular pathology (acute coronary syndrome)
Authors: Kopytsia M. P. , Rodionova Yu. V. , Tytarenko N. V. , Kutia I. M. , Нilоva Ya. V. 
Published: October 2021

Myeloperoxidase is one of the key enzymes involved in oxidative stress and inflammation. Its elevated levels are determined in a wide range of both acute and chronic forms of cardiovascular diseases. The inflammation results in the release of the enzyme from the white blood cells to form products such as hypochlorous acid, which in turn can have a negative effect on the target proteins. Inconsistent evidence on the predictive role of this biomarker in diseases of the circulatory system generates scientific interest and provokes further research in this direction.
The aim of this review is to analyze the scientific literature data on myeloperoxidase as a possible clinical use for the diagnosis and risk stratification of patients with саrdiovascular diseases.
Materials and methods. Searching and generalization of data from leading specialized sources, which are indexed by scientific databases PubMed, SCOPUS, Web of Science.
Results. The results of the studies indicate that myeloperoxidase is actively involved in the pathophysiology of cardiovascular diseases through participation in oxidative stress and inflammation, excessive production of proatherogenic lipoproteins, changes in nitric oxide activity, endothelial dysfunction, and due to the effect on the instability of atherosclerotic plaques. In patients with cardiovascular diseases, including ischemic heart disease, the concentration of the indicated protein is increased and is often associated with a poor prognosis, including an increased risk of mortality. Myeloperoxidase metabolites are often the factors that contribute to cell damage under conditions of ischemia. The review also considers the relationship of the enzyme with the development of restenosis and the effectiveness of revascularization after percutaneous coronary intervention.
Conclusions. The presented data mainly define myeloperoxidase as a significant marker for predicting long-term follow-up results and the development of serious adverse cardiovascular events, mortality in patients with cardiovascular disease. At the same time, despite the great achievements in disclosing the complex effects of myeloperoxidase, inconsistency in the available results is noteworthy. This controversy necessitates further research to elucidate and reveal the full clinical potential of myeloperoxidase in patients with cardiovascular pathology.
Studying Depression, Anxiety, Distress and Somatization in a Community Sample of 2,425 Adults in Greece
Authors: Louvardi Maya , Pelekasis Panagiotis , Bacopoulou Flora , Vlachakis Dimitrios , Chrousos George , Darviri Christina 
Published: October 2021

A growing part of the literature has focused on depression, anxiety, distress and somatization. Identifying their prevalence and recording high-risk populations is essential in order to form relevant interventional programs addressing these symptoms. The aim of this study was to examine the prevalence and associated factors of distress, depression, anxiety and somatization in a community adult sample in Greece. Participants were recruited from two Greek cities; Giannitsa in the northern area and Athens in the southern area of the country and completed sociodemographic assessments, as well as the 4-Dimensional Symptom Questionnaire (4-DSQ), a self-reported instrument assessing depression, anxiety, distress and somatization.A total of 2,425 adults, females (60.1%) and males (39.9%), 18 to 84 years of age (mean age 46.98 ± SD) participated in the study. Mental health symptoms were reported by 10.8% for depression, 12% for anxiety, 13% for distress and 5.3% for somatization of the participants. Females scored higher than males in anxiety, distress, and somatization (p=0.000 in all cases), while there were no significant sex differences in depression (p=0.593). Statistically significant associations were found between age and depression, anxiety and distress (p=0.000 in all cases), since those between 18-34 years of age had higher scores than the older age groups in all variables. Higher scores of depression, anxiety and distress were reported by students and unemployed participants (p=0.000 in all cases) than participants with other occupations. This study mapped several sociodemographic groups with worse mental health. Studies in representative population samples are needed to guide public health interventions to improve the mental and physical well-being of high-risk populations.
Embodiment, Autoethnography, Performance Poetry:  Living with Severe Traumatic Brain Injury
Authors: Kidd Douglas E. 
Published: October 2021

This presentation offers neurodivergence embodied, autoethnography, and performance poetry. The confluence of acquiring severe traumatic brain injury combined with exposure to concepts and paradigms while pursuing a graduate degree in Disability Studies, catalyzed emergence and triggered development of my disabled identity. The brain damage acquired causes issues of decoding/deciphering/processing, which in turn triggers and/or produces episodes of temporal dissonance. When these shifts in timing occur, they have tremendous impact on rational thought processes and emotional stability. The salient aspects of my new life – emotional sensitivity and volatility – may on the surface seem detrimental and undesirable; however, I celebrate these qualities as they greatly enhance my identification with and empathy for others, which in turn drive my artistic, social, cultural, political expression, quest for community and belonging. While temporal dissonance is unlikely to occur during this planned short presentation, I will relate and provide the audience with windows on largely hidden and little understood forms of impairment.

Note: To hear recitation of some of these poems, check out fellow VIBE presenter Cheryl Green’s podcast: http://whoamitostopit.com/pigeonhole-podcast-17-autoethnographic-poetry/

The original presentation at VIBE was accompanied by music from Miles Davis and Marcus Miller’s 1987 album Music from Siesta. Readers are encouraged to listen to this album via their music platform of choice while reading the following poetry. Youtube link to the album: https://www.youtube.com/watch?v=ZuvtNL_jyeQ
Raising the Bar in Disability Arts
Authors: Nagrani Menka 
Published: October 2021

This article discusses my pedagogical approach towards teaching dance, movement, and theatre to artists with cognitive disabilities. I have developed a training method for artists participating in my classes and productions that invites individual creative exploration and professional rigour. My inclusive dance-theatre company, Les Productions des pieds des mains, creates productions that are presented on professional artistic platforms and not limited to the context of disabled art presentations. Our productions are regularly subject to the same selection criteria as would be a non-inclusive company. With this in mind, I aim for excellence. I work towards creating high quality shows while helping artists with a disability push past their perceived limits and surpass themselves. In this article I will share my findings and strategies, perfected throughout my many years of experimentation, explaining how to reach a high-level of quality in inclusive productions, as well as how I help artists with a disability reach a level of quality in their performances which allows them to find gainful employment within the artistic domain.
…and this is my voice: autopathophonography and the politics of variable voice
Authors: Sterne Jonathan 
Published: October 2021

This essay describes the production and theoretical context of an audio work entitled “…and this is my voice.” In May and June 2010, I took recordings of my voice while on the way into external beam radiation treatments for an aggressive case of papillary thyroid cancer in my neck. I then used these recordings as the raw material for the work. This essay provides full documentation of the production process for those who may want or need something beyond the original audio work to engage with it fully, as well as a theoretical discussion of the ideology of vocal ability: the belief that voices are expressions of subjects’ inner states and abilities.

Work available at: https://jonathansterne.bandcamp.com/track/and-this-is-my-voice
A UNIFIED APPROACH TO EXPONENTIAL STABILITY ANALYSIS FOR A GENERAL CLASS OF SWITCHED TIME-DELAY LINEAR SYSTEMS
Authors: Khoa Son Nguyen , Le Ngoc Van 
Published: October 2021

This paper proposes a unified approach to study global exponential stability for a class of switched time-delay linear systems described by general linear functional differential equations. Several new delay-dependent criteria of exponential stability are established for this class of systems, under arbitrary switching which satisfies some assumptions on the minimum dwell time or the average dwell time. As particular cases, the obtained results are shown to include and improve many previously known results. An example is given to illustrate the proposed method.
Diagnósticos de enfermagem em pacientes neurológicos: estudo documental
Authors: Mayron Morais Soares Francisco , Batista Mesquita Kirley Kethellen , Eduarda Silva Praciano Teles Lana , Damasceno Pequeno Carlos Lucas , Magalhães Davi Santos , Freitas Julyana Gomes 
Published: October 2021

OBJETIVO: identificar o perfil sociodemográfico e clínico e os diagnósticos de enfermagem em pacientes neurológicos. MÉTODO: Estudo documental realizado entre dezembro de 2017 e março de 2018, com 184 prontuários em um hospital terciário da região nordeste do Brasil. Os dados foram coletados mediante instrumento com perfil sociodemográfico e clínico e apresentados por meio da estatística descritiva. RESULTADOS: A maioria dos pacientes era do sexo masculino e com diagnóstico médico de traumatismo cranioencefálico. Foi observado um total de 25 títulos de diagnósticos de enfermagem, e os que mais prevaleceram foram glicemia instável, confusão aguda, queda, déficit do autocuidado, deambulação prejudicada e conforto prejudicado. Percebe-se a predominância dos diagnósticos de enfermagem para os pacientes neurológicos nos domínios de nutrição e autocuidado. CONCLUSÃO: Os diagnósticos de enfermagem identificados neste estudo podem contribuir para o incremento de indicadores sensíveis à prática de enfermagem e favorece a assistência direcionada as necessidades do paciente.
USING THE SeDeM-ODT METHOD FOR THE DEVELOPMENT OF GK-2 TABLETS DISPERSED IN THE ORAL CAVITY
Authors: Tishkov S. V. , Blynskaya E. V. , Alekseev K. V. , Buyeva V. V. 
Published: October 2021

Introduction. The SeDeM-ODT method is a relatively new method based on expert judgment and pie charts, which reflect 15 main parameters of the suitability of a dosage form for direct compression and dispersibility in the oral cavity.The purpose of the research presented in this article is to study the pharmaceutical substance (API) GK-2 (bis- (N-monosuccinyl-L-glutamyl-L-lysine)hexamethyleneamide) using the SeDeM-method, to determine the direction for the correction of technological properties using excipients and to develop using the presented methods of the composition of tablets GK-2, dispersible in the oral cavity.Materials and methods. Preparation of tablets – manual hydraulic press PRG-50; method for determining flowability (GPM.1.4.2.0016.15, GP XIV, volume 2) – bulk density analyzer (ERWEKA SVM 221), GTB flowability tester (ERWEKA, Germany); crushing strength of tablets (GPM.1.4.1.0011.15, GP XIV, volume 2) – strength analyzer TBF 1000 CopleyScientific® (Great Britain); method for determining disintegration (GPM.1.4.2.0013.15, GP XIV edition, volume 2) – PTZ-S disintegration tester (Pharma Test, Germany); weight loss on drying (GPM.1.2.1.0010.15, GP XIV edition, volume 1) – moisture analyzer Sartorius MA-35 (Sartorius AG, Germany); determination of fractional composition – a vibrating sieve with pore sizes: 850, 600, 425, 300 and 250 microns, is used to determine the particle size distribution; tablet abrasion tester (GPM.1.4.2.0004.15, GP XIV edition, volume 2) – tablet abrasion tester PTF 30 ERA (Pharma Test, Germany); Optical microscopy (GPM.1.2.1.0009.15, GP XIV edition, volume I) – microscope Nicon, Eclipse E 200; digital camera Nicon Ds-Ri2. The data were processed using the SeDeM and SeDeM-ODT methods.Results. Model formulations have been developed containing various types of co-process fillers and a sliding excipient, which have been studied using the main pharmaceutical-technological methods and optical microscopy. Based on the data obtained, SeDeM-ODT diagrams were constructed, in which the parameters were converted into “radii”, reflecting the degree of acceptability for each technological characteristic. In addition, the following factors were calculated from the pie charts: volumetric parameter, compressibility coefficient, flowability parameter, stability coefficient, dosage coefficient, dispersibility coefficient, as well as the index of good pressing, the parametric index and the parametric index of the profile.Conclusion. As a result of the data obtained, the most optimal composition was selected that was acceptable for all the factors under consideration and had the highest values of the parametric index.
An economic evaluation of pre-dialysis stage of chronic kidney disease
Authors: Rumiantseva E. I. , Avxentyeva M. V. 
Published: October 2021

Objective: to review clinical and economic studies on the pre-dialysis stage of chronic kidney disease (CKD) and the cost-effectiveness of medical interventions used to detect CKD and prevent its progression.Material and methods. Articles were collected from the bibliographic databases PubMed, Cochrane Library and eLibrary for 2010–2020. Keywords for the search: ‘chronic kidney disease (CKD)’, ‘cost-effectiveness’, ‘economic evaluation’, ‘economic burden’, ‘cost’, ‘healthcare’. After the selection and elimination of the repeated articles, we reviewed 36 Russian and foreign studies on the economic burden of CKD and the clinical and economic effectiveness of various medical interventions of the CKD pre-dialysis stage.Results. We found 21 studies on the economic burden of CKD. A significant part of them (n=6) was performed in the United States.The methodology for assessing the economic burden varied significantly from study to study. Studies on medical interventions at the CKD predialysis stage can be divided into three groups: Group 1 (n=9) – studies on the clinical and economic effectiveness of screening programs; Group 2 (n=3) – studies on the clinical and economic effectiveness of nephroprotectors and other drugs that slow down the course of CKD; and Group 3 (n=3) – studies on the clinical and economic effectiveness of multidisciplinary care. We concluded on the clinical and economic feasibility of most interventions that were used to detect CKD and prevent its progression.Conclusion. We did not find any scientific data that could currently serve as a justification for the clinical and economic feasibility of CKD control programs in the Russian Federation. At the same time, studies conducted in foreign countries on the screening for CKD and some interventions aimed at slowing the progression of CKD suggest that in the Russian Federation, such approaches can be justified not only clinically, but also economically. It is necessary to conduct domestic research on the clinical and economic feasibility of interventions aimed at identifying and treating CKD at an early stage.
The Recuperation of Sacrifice
Authors: Fagerberg David W. 
Published: October 2021

Przywrócenie znaczenia ofiary
Ofiarniczy wymiar Mszy świętej mógłby być lepiej zrozumiany, jeśli na nowo przywrócilibyśmy pojęcie „ofiary”. Powszechne, świeckie rozumienie ofiary ujmuje ją w kategoriach straty, smutku i rezygnacji z czegoś, podczas gdy biblijne, teologiczne rozumienie widziane jest w kategoriach daru, radości i dawania Bogu. Dlatego w artykule poddano analizie ofiarę w trzech kontekstach, w których się ona dokunuje: niewinności, grzechu i Osoby Chrystusa. Pierwszy z nich to kosmiczna liturgia homo adorans, sprawowana w stanie pierwotnej sprawiedliwości. Drugi to skażona po grzechu forma ofiary oczekującej na odkupienie. Trzecia to ofiara krzyża, w której łaska udoskonala naturę, a pierwotne znaczenie ofiary zostaje przywrócone. Ofiarny Chrystus – kapłan i ofiara – oddaje się członkom swojego mistycznego ciała, aby formować ich do prawdziwej ofiary.
The Liturgical Offering of Boredom
Authors: O'Malley Timothy P. 
Published: October 2021

Znudzenie podczas ofiary liturgicznej
Czy istnieje coś takiego jak nudny rytuał, czy raczej nuda jest afektywnym przeżyciem podmiotu? W artykule autor stawia tezę, że nic – łącznie z posoborowymi obrzędami Kościoła – nie może być z natury nudne. Nuda – lub wyraźniej poddanie się nudzie – jest duchową chorobą późnej nowoczesności. Artykuł wychodzi od analizy zjawiska nudy, ze szczególnym uwzględnieniem nudy w jakiejś cyfrowej ekologii. Następnie zwrócono uwagę na symptomy nudy badane przez teoretyków społecznych i kulturowych w ciągu ostatniej dekady, w tym Zygmunta Baumana, Harmuta Rosę i Byung-Chul Hana. Na koniec poddano analizie Ducha liturgii Romano Guardiniego jako dającej lekarstwo na pewien rodzaj antyświątecznej kultury, która jest źródłem nudy w późnej nowoczesności. Nuda nie jest problemem związanym z obrzędem, ale ze świadomością samego człowieka, który nie nauczył się jeszcze uczestniczyć w autentycznej radości aktu kultu.
STUDY OF VOLUME CHANGES OF PLASTER WITH MINERAL ADDITIVES
Authors: Іefimenko Artem 
Published: October 2021

Pre-treatment viznachaє infusion of mineral additives on the natural deformation of gypsum virob. The main reason for the low water resistance of the gypsum viruses is stated. The reason is є a wedge vise. Such a grip breaks out local contacts with crystals. Tsi cause one to dress up in a negative synergistic effect. A wide circle of naukovts is looked around. Fakhivtsi detect the inflow of mineral and chemical additives on the water resistance of the gypsum. Zokrem is honored that the power of materials on the basis of inorganic viscous accumulation of the manifestation of electrostatic interconnection of subordinate electric spheres of structural elements.
Before it was confirmed, the value of the biological deformation of the gypsum should be deposited instead of a mineral supplement. Uwagu zoseredzheno on slag blast-furnace granulated chalk.The meta of the statistic was the determination of the degree of determination of the indicator of the uniform lineal deformation of the water saturation (swelling) ew at m / m. Such an indicator can be used with a supplementary indicator of water resistance. In the experimental preliminaries, we used G-10 grade G-10 industrial gypsum, Zaporizhstal blast-furnace granulation slag, and a plasticizing additive - sodium lignosulfonate in a 2% mixture of gipsuFor further development, the skin with three eyes was placed vertically near the vessel. A steel overlay was placed on top of the zrazok. Before the overlay, an indicator of the year-old type was set, fastened to a laboratory stand. The distance was fixed to the cob to show the indicator. The deformation took 3–5 years to develop. In the meantime, having reached the maximum value and mayzhe, the odra was repaired to decrease. At the same time, there will be a projection of the addition of a supplementary indicator of water resistance to the water consumDue to the increase in the amount of slag, the deformation will decrease. The price decrease did not demonstrate a linear character. The character is sickly. This deposit is analogous to that of the deposits of the mines and water from the slag. Minimal deformation is more favorable for a piece gypsum stone with a removable slag W / (H + W) 0.05–0.1 and ponad 0.27. Tse pіdtverzhu podpuschennya about injections at low water resistance gіpsu ozklinuvalnogo inlet water. The wedge-shaped inflow of water is drawn through the contacts between the crystals and particles in the structures of the hypers. The values of the natural deformations of a piece gypsum stone are projected according to the parameters of the water resistance.
​Yield of Spring Wheat with the Combined Use of Sodium Selenite and Growth Regulators Depending on the Conditions of Water Supply
Authors: Seregina I. , Chernyshev D.A. , Trukhachev V.I. , Belopukhov S.L. , Dmitrevskaya I.I. , Zaitsev F.I. 
Published: October 2021

Background: Currently, technologies that provide the energy and nutritional value of agricultural crops under extreme growing condishions have the greatest advantage. Much research is devoted to the study of the effect of brassinosteroids and their analogs, as well as zircon, which have a multifunctional effect on the yield and the formation of elements of productivity of various agricultural plants. Also many studies have been carried out to study the effect of microelements on the formation of yield and adaptive ability of grain crops. However, some aspects of increasing the efficiency of growth regulation and microelements require further study. In this regard, studies were carried out to study the effect of the combined use of growth regulators and sodium selenite on the yield and the formation of productivity elements of spring wheat, depending on the conditions of water supply. The efficiency of the action of plants growth epin and zircon, introduced together with sodium selenit, on the yield and production process of spring wheat plants under conditions of optimal irrigation and short-term soil drought has been studies. Methods: The research was carried out in 2018-2019. In a vegetation experiment at the Russian State Agarian University-Moscow Agricultural Academy. The object of research was spring soft wheat of the Ivolga variety. The plants were grown in vessels with a capacity of 5 kg of soil. For the experiments, a soddy-podzolic medium loamy soil was used. The optimal conditions for water supply were created watering the vessels during the entire growing season. A short-trem drought was created by stopping irrigation duting the steming phase. The duration of the drought is 5-6 days. In experiments, growth regulations epin, zircon and sodium selenite were studied, which were used by treating seeds before sowing wich 0,01% solutions of preparations. In the studies, the yield of spring wheat ang the formation of productivity elements were determined. Result: Analysis of variance results for differences in the action of sodium selenite, zircon and epin, as well as their combination on various aspects of the production process of forming wheat yield. The stimulating effect of the combined use of sodium selenite and zircon on the reproductive organs of wheat was established, as a result of cariopses in an ear increased by 1.43 time. The activation of the attracting ability of the ear established when using the conscientious use of sodium selenite and epin. As a result, the wheat yield increased by 20% with optimal water supply and drought.