bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Bath Agitation on the Transient Cooling by Quenching Process
Authors: Kacem Amine , Bourouga Brahim , Ould El Moctar Ahmed 
Published: August 2021

Abstract
During the quenching process, the liquid bath is usually agitated to homogenize the temperature and to enhance convective heat transfer. The purpose of this paper is to characterize on the one hand the agitation of a water bath due to the movement of a three-blade turbine and on the other, the cooling of an Inconel 718 part being quenched in a stirred water bath. Velocity measurements were taken by particle image velocimetry (PIV) with and without the metallic part. We found that the velocity field became purely axial when we were far enough away from the turbine. Moreover, a high turbulent mixing level was shown for this type of jet. Velocity measurements were carried out for two agitation intensities. The axial velocity amplitude, as well as the turbulent kinetic energy, decreased dramatically as the rotational speed of the propeller decreased from 410 to 100 rpm. This caused the thermal behavior of the part to differ during quenching. Indeed, we found that the part cooled faster under stronger agitation. During the film boiling and transition phases, no appreciable effect of agitation could be observed. However, from the middle of the nucleate boiling phase, the part-bath heat transfer coefficient was found to decrease much less rapidly with the surface temperature if agitation was strong than if it was weak or if the bath was completely calm. In such a case of strong agitation, both nucleate boiling and convection concomitantly ensure part cooling.
Advanced Temperature Control Applied on An Industrial Box Furnace
Authors: Tudon-Martinez Juan C. , Lozoya-Santos Jorge de-J. , Cantu-Perez Alberto , Cardenas-Romero Andrea 
Published: August 2021

Abstract
The current control system of an industrial box furnace usually uses a proportional-integral-derivative (PID) controller. Typically, this control system requires on-site tuning and specific heuristic knowledge, such that the furnace can have acceptable performance but not optimal. However, by using a proper model in the operating range of the furnace from the designing phase, it can be designed a more efficient control system capable to reach better performance in this industrial process. In this sense, the main objective of this paper is the design and validation of an advanced control strategy in the early design stage of an industrial box furnace. The goals are to decrease the controller tuning time during the furnace commissioning process, improve the furnace performance with respect to classical industrial controllers, and decrease the system energy expenses. Thus, a comparative analysis in a simulated environment has been carried out between the performance of a PID controller by its typical industrial use, a model predictive control (MPC) due to the optimal results in similar industrial processes, and a virtual reference feedback tuning (VRFT) control by its feasibility of implementation. Results show that the advanced MPC and VRFT controllers are more efficient in the used fuel/gas than the PID. MPC shows the best balance between performance and actuation, it improves the control performance up to 87.2% with respect to the VRFT controller.
Developing a health economic model for Asians with type 2 diabetes based on the Japan Diabetes Complications Study and the Japanese Elderly Diabetes Intervention Trial
Authors: Tanaka Shiro , Langer Jakob , Morton Tim , Hoskins Nicki , Wilkinson Lars , Tanaka-Mizuno Sachiko , Kawasaki Ryo , Moriya Tatsumi , Horikawa Chika , Aida Rei , Araki Atsushi , Fujihara Kazuya , Sone Hirohito 
Published: August 2021

IntroductionCost-effectiveness analyses are becoming increasingly important in Japan following the introduction of a health technology assessment scheme. The study objective was to develop an economic model to evaluate the cost-effectiveness of two interventions for type 2 diabetes in a Japanese population.Research design and methodsThe Japan Diabetes Complications Study/Japanese Elderly Diabetes Intervention Trial risk engine (JJRE) Cost-Effectiveness Model (JJCEM) was developed, incorporating validated risk equations in Japanese patients with type 2 diabetes from the JJRE. Weibull regression models were developed for progression of the model outcomes, and a targeted literature review was performed to inform default values for utilities and costs. To illustrate outcomes, two simulated analyses were performed in younger (aged 40 years) and older (aged 80 years) Japanese populations, comparing a hypothetical treatment with placebo.ResultsThe model considers a population based on user-defined values for 11 baseline characteristic parameters and simulates rates of diabetic complications over a defined time horizon. Costs, quality-adjusted life years, and an incremental cost-effectiveness ratio are estimated. The model provides disaggregated results for two competing interventions, allowing visualization of the key drivers of cost and utility. A scatterplot of simulations and cost-effectiveness acceptability curve are generated for each analysis.ConclusionsThis is the first cost-effectiveness model for East Asian patients with type 2 diabetes, developed using Japan-specific risk equations. This population constitutes the largest share of the global population with diabetes, making this model highly relevant. The model can be used to evaluate the cost-effectiveness of anti-diabetic interventions in patients with type 2 diabetes in Japan and other East Asian populations.
Update on Noma: systematic review on classification, outcomes and follow-up of patients undergoing reconstructive surgery after Noma disease
Authors: Speiser Sophie , Langridge Benjamin , Birkl Moira Melina , Kubiena Harald , Rodgers Will 
Published: August 2021

IntroductionNoma is a significant yet neglected disease which affects some of the least developed countries in the world. The long-term benefit and safety of Noma surgical reconstructive missions have recently been under scrutiny due to a perceived lack of measurable outcomes and appropriate follow-up. This study analyses and reports on classifications, outcome measurement tools and follow-up for reconstructive surgery after Noma disease.MethodsThis systematic review was undertaken following Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. The three medical databases Medline, EMBASE and Web of Sciences were searched, articles published between 1 January 1983 and 15 April 2020 were included. All primary evidence on reconstructive surgery following Noma disease, reporting data on outcome after surgery, follow-up time and complications were included. Extracted data were aggregated to generate overall and population corrected mean outcomes and complication rates.ResultsOut of 1393 identified records, 31 studies including 1110 Noma patients were analysed. NOITULP and Montandon/WHO were the most commonly used classification systems. Mouth opening (MO) and complication rates were the two most often reported outcomes. Overall mean complication rate was 44%, reported by 24 studies. Postoperative MO was reported by eight publications, of which, five reported long-term outcomes (>12 months). Mean MO improved by 20 mm when compared with mean population weighted preoperative MO (7 mm). At long-term follow-up, MO decreased to 20 mm.ConclusionsStudies reporting on neglected diseases in developing countries often lack methodological rigour. Surgeons should be mindful during patient examination by using a classification system that allows to compare preoperative versus postoperative state of disease. Short-term mission surgery is a vital part of healthcare delivery to underdeveloped and poor regions. Future missions should aim at sustainable partnerships with local healthcare providers to ensure postoperative care and long-term patient-oriented follow-up. A shift towards a diagonal treatment delivery approach, whereby local surgeons and healthcare staff are educated and empowered, should be actively promoted.PROSPERO registration numberCRD42020181931.
Common factors in serious case reviews of child maltreatment where there is a medical cause of death: qualitative thematic analysis
Authors: Garstang Joanna , Eatwell Daisy , Sidebotham Peter , Taylor Julie 
Published: August 2021

AimTo identify the common factors in serious case reviews (SCRs) where a child has died of a medical cause.DesignQualitative thematic analysis.BackgroundSCRs take place when neglect or abuse results in children dying or being seriously harmed. Known key factors within SCRs include parental substance misuse, mental health problems and domestic abuse. To date, there has been no investigation of children who die of a medical cause where there are concerns about child maltreatment.Data sourcesA list of SCRs relating to deaths through medical causes was provided from previous coded studies and accessed from the National Society for the Prevention of Cruelty to Children National Case Review Repository. Twenty-three SCRs with a medical cause of death from 1 April 2009 to 31 March 2017 were sourced.Results20 children died of an acute condition and 12 of a chronic condition; 20 of the deaths were unexpected and maltreatment contributed to the deaths of 18 children. Most children were aged either <1 year or >16 years at the time of death. Many parents were caring for a child with additional vulnerabilities including behavioural issues (6/23), learning difficulties (6/23), mental health issues (5/23) or a chronic medical condition (12/23). Common parental experiences included domestic violence/abuse (13/23), drug/alcohol misuse (10/23), mental ill health or struggling to cope (7/23), criminal history (11/23) and caring for another vulnerable individual (8/23). Most children lived in a chaotic household characterised by missed medical appointments (18/23), poor school attendance (11/23), poor physical home environment (7/23) and disguised compliance (12/23). All 23 SCRs reported elements of abusive or neglectful parenting. In most, there was an evidence of cumulative harm, where multiple factors contributed to their premature death. At the time of death, 11 children were receiving social care support.ConclusionAlthough the underlying medical cause of the child’s death was often incurable, the maltreatment that often exacerbated the medical issue could have been prevented.
Quantifying conflict zones as a challenge to certification of Guinea worm eradication in Africa: a new analytical approach
Authors: Kelly-Hope Louise A , Molyneux David H 
Published: August 2021

ObjectivesTo quantify conflict events and access across countries that remain to be certified free of transmission ofDracunculus medinensis(Guinea worm disease) or require postcertification surveillance as part of the Guinea Worm Eradication Programme (GWEP).Setting and participantsPopulations living in Guinea worm affected areas across seven precertification countries and 13 postcertification sub-Saharan African countries.Outcome measuresThe number of conflict events and rates per 100 000 population, the main types of conflict and actors reported to be responsible for events were summarised and mapped across all countries. Chad and Mali were presented as case studies. Guinea worm information was based on GWEP reports. Conflict data were obtained from the Armed Conflict Location and Event Data Project. Maps were created using ArcGIS V.10.7 and access was measured as regional distance and time to cities.ResultsMore than 980 000 conflict events were reported between 2000 and 2020, with a significant increase since 2018. The highest number and rates were reported in precertification Mali (n=2556; 13.0 per 100 000), South Sudan (n=2143; 19.4), Democratic Republic of Congo (n=7016; 8.1) and postcertification Nigeria (n=6903; 3.4), Central Africa Republic (n=1251; 26.4), Burkina Faso (n=2004; 9.7). Violence against civilians, protests and battles were most frequently reported with several different actors involved including Unidentified Armed Groups and Boko Haram. Chad and Mali had contracting epidemiological and conflict situations with affected regions up to 700 km from the capital or 10 hours to the nearest city.ConclusionsUnderstanding the spatial–temporal patterns of conflict events, identifying hotspots, the actors responsible and their sphere of influence is critical for the GWEP and other public health programmes to develop practical risk assessments, deliver essential health interventions, implement innovative surveillance, determine certification and meet the goals of eradication.
Built environments for inpatient stroke rehabilitation services and care: a systematic literature review
Authors: Lipson-Smith Ruby , Pflaumer Luis , Elf Marie , Blaschke Sarah-May , Davis Aaron , White Marcus , Zeeman Heidi , Bernhardt Julie 
Published: August 2021

ObjectivesTo identify, appraise and synthesise existing design evidence for inpatient stroke rehabilitation facilities; to identify impacts of these built environments on the outcomes and experiences of people recovering from stroke, their family/caregivers and staff.DesignA convergent segregated review design was used to conduct a systematic review.Data sourcesOvid MEDLINE, Scopus, Web of Science and Cumulative Index to Nursing and Allied Health Literature were searched for articles published between January 2000 and November 2020.Eligibility criteria for selecting studiesQualitative, quantitative and mixed-methods studies investigating the impact of the built environment of inpatient rehabilitation facilities on stroke survivors, their family/caregivers and/or staff.Data extraction and synthesisTwo authors separately completed the title, abstract, full-text screening, data extraction and quality assessment. Extracted data were categorised according to the aspect of the built environment explored and the outcomes reported. These categories were used to structure a narrative synthesis of the results from all included studies.ResultsTwenty-four articles were included, most qualitative and exploratory. Half of the included articles investigated a particular aspect of the built environment, including environmental enrichment and communal areas (n=8), bedroom design (n=3) and therapy spaces (n=1), while the other half considered the environment in general. Findings related to one or more of the following outcome categories: (1) clinical outcomes, (2) patient activity, (3) patient well-being, (4) patient and/or staff safety and (5) clinical practice. Heterogeneous designs and variables of interest meant results could not be compared, but some repeated findings suggest that attractive and accessible communal areas are important for patient activity and well-being.ConclusionsStroke rehabilitation is a unique healthcare context where patient activity, practice and motivation are paramount. We found many evidence gaps that with more targeted research could better inform the design of rehabilitation spaces to optimise care.PROSPERO registration numberCRD42020158006.
Perceived anxiety and physical activity behaviour changes during the early stages of COVID-19 restrictions in community-dwelling adults in Canada: a cross-sectional study
Authors: McCormack Gavin R , Doyle-Baker Patricia K , Petersen Jennie A , Ghoneim Dalia 
Published: August 2021

ObjectivesThe COVID-19 pandemic changed daily routines, including physical activity, which could influence physical and mental health. In our study, we describe physical activity and sedentary behaviour patterns in relation to the pandemic and estimate associations between anxiety and physical activity and sedentary behaviour in community-dwelling adults.DesignCross-sectional study.SettingCalgary, Alberta, Canada.ParticipantsBetween April and June 2020, a random sample of 1124 adults (≥18 years) completed an online questionnaire.Primary and secondary outcomesThe online questionnaire captured current walking, moderate intensity, vigorous intensity and total physical activity and sedentary behaviour (ie, sitting and leisure-based screen time), perceived relative changes in physical activity, sedentary and social behaviours since the pandemic, perceived seriousness and anxiety related to COVID-19, and sociodemographic characteristics. Differences in sociodemographic characteristics, perceived relative change in behaviour and current physical activity and sedentary behaviour were compared between adults with low and high anxiety.ResultsOur sample (n=1047) included more females (60.3%) and fewer older adults (19.2%). Most participants (88.4%) considered COVID-19 as extremely or very serious and one-third (32.9%) felt extremely or very anxious. We found no differences (p>0.05) in current physical activity or sedentary behaviour by anxiety level. The largest perceived change in behaviours included social distancing, driving motor vehicles, use of screen-based devices, watching television and interactions with neighbours. We found anxiety-related differences (p<0.05) in perceived changes in various behaviours.ConclusionsChanges in physical activity, sedentary behaviour and social behaviour occurred soon after the COVID-19 pandemic was declared, and some of these changes differed among those with low and high anxiety.
Psyllium reduces inulin-induced colonic gas production in IBS: MRI andin vitrofermentation studies
Authors: Gunn David , Abbas Zainab , Harris Hannah C , Major Giles , Hoad Caroline , Gowland Penny , Marciani Luca , Gill Samantha K , Warren Fred J , Rossi Megan , Remes-Troche Jose Maria , Whelan Kevin , Spiller Robin C 
Published: August 2021

ObjectiveHealth-promoting dietary fibre including inulin often triggers gastrointestinal symptoms in patients with IBS, limiting their intake. Our aim was to test if coadministering psyllium with inulin would reduce gas production.DesignA randomised, four-period, four-treatment, placebo-controlled, crossover trial in 19 patients with IBS. Subjects ingested a 500 mL test drink containing either inulin 20 g, psyllium 20 g, inulin 20 g+ psyllium 20 g or dextrose 20 g (placebo). Breath hydrogen was measured every 30 min with MRI scans hourly for 6 hours. Faecal samples from a subset of the patients with IBS were tested using anin vitrofermentation model. Primary endpoint was colonic gas assessed by MRI.ResultsColonic gas rose steadily from 0 to 6 hours, with inulin causing the greatest rise, median (IQR) AUC(0–360 min)3145 (848–6502) mL·min. This was significantly reduced with inulin and psyllium coadministration to 618 (62–2345) mL·min (p=0.02), not significantly different from placebo. Colonic volumes AUC(0–360 min)were significantly larger than placebo for both inulin (p=0.002) and inulin and psyllium coadministration (p=0.005). Breath hydrogen rose significantly from 120 min after inulin but not psyllium; coadministration of psyllium with inulin delayed and reduced the maximum increase, AUC(0–360 min)from 7230 (3255–17910) ppm·hour to 1035 (360–4320) ppm·hour, p=0.007.Fermentationin vitroproduced more gas with inulin than psyllium. Combining psyllium with inulin did not reduce gas production.ConclusionsPsyllium reduced inulin-related gas production in patients with IBS but does not directly inhibit fermentation. Whether coadministration with psyllium increases the tolerability of prebiotics in IBS warrants further study.Trial registration numberNCT03265002.
Bi-directional associations between religious attendance and mental health: findings from a British birth cohort study
Authors: Kaushal Aradhna , Stafford Mai , Cadar Dorina , Richards Marcus 
Published: August 2021

BackgroundThere is evidence that religious attendance is associated with positive outcomes for mental health; however, there are few longitudinal studies, and even fewer, which take into account the possibility of bi-directional associations. This study aimed to investigate bi-directional associations between religious attendance and mental health.MethodsParticipants were 2125 study members who provided data at age 68–69 from the Medical Research Council National Survey of Health and Development (1946 British birth cohort study). Mental health was assessed using the 28-item General Health Questionnaire at ages 53, 60–64 and 68–69. Religious attendance was measured using a 4-point scale (weekly=3, monthly=2, less than monthly=1 or never=0) at ages 43, 60–64 and 68–69. Cross-lagged path analysis was used to assess reciprocal associations between mental health and religious attendance, adjusting for gender and education.ResultsPrevious religious attendance was strongly related to later attendance (r=0.62–0.74). Similarly, mental health at baseline was strongly associated with subsequent mental health scores (r=0.46–0.54). Poor mental health at age 53 and 60–64 was associated with more frequent religious attendance at age 60–64 (b=0.04; 95% CI: 0.02 to 0.06; p<0.05), and 68–69 (b=0.03; 95% CI: 0.02 to 0.06; p<0.05), respectively. There was no evidence that religious attendance at age 43, 60–64 or 68–69 was associated with later or concurrent mental health.ConclusionUsing birth cohort data from the UK, it was found that poor mental health was associated with later religious attendance but not vice versa. Future research should confirm these novel findings and explore the underlying mechanisms between religious attendance and mental health.
Violent victimisation trajectories from adolescence through adulthood: consequences for sleep problems
Authors: Testa Alexander , Semenza Daniel C , Jackson Dylan B 
Published: August 2021

BackgroundViolent victimisation is a stressful experience that has been linked with sleep problems among children, adolescents and adults. However, prior research has not assessed how victimisation trajectories across different stages of the life-course correspond to sleep outcomes. The present study assesses how trajectories of violent victimisation from adolescence to middle adulthood correspond to sleep behaviours in adulthood.MethodsData are from fives waves of the National Longitudinal Study of Adolescent to Adult Health (N=6015). Semi-parametric group-based trajectory modelling was used to estimate violent victimisation trajectories from adolescence to middle adulthood. Multinomial logistic regression was used to assess the association between sleep quantity and quality across violent victimisation trajectories.ResultsThe findings demonstrate that the relationship between violent victimisation and sleep in adulthood is not consistent across all victimisation trajectories. Rather, sleep quality and quantity are the worst among those who persistently experience violent victimisation from adolescence through adulthood.ConclusionPersistent exposure to violence can be a particularly damaging experience with consequences for sleep quantity and quality. Establishing interventions that reduce violent victimisation across the life-course and promote positive sleep behaviours among those with a history of victimisation are important public health measures.