bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of moist and oven-dried bacterial cellulose production for functional properties
Authors: Bodea Ioana Maria , Beteg Florin Ioan , Pop Carmen Rodica , David Adriana Paula , Dudescu Mircea Cristian , Vilău Cristian , Stănilă Andreea , Rotar Ancuța Mihaela , Catunescu Giorgiana Mihaela 
Published: February 2021

Abstract
Bacterial cellulose (BC) is a natural polymer with properties suitable for tissue engineering and possible applications in scaffold production. However, current procedures have limitations in obtaining BC pellicles with the desired structural, physical, and mechanical properties. Thus, this study analyzed the optimal culture conditions of BC membranes and 2 types of processing: draining and oven-drying. The aim was to obtain BC membranes with properties suitable for a wound dressing material. Two studies were carried out. In the preliminary study the medium (100 mL) was inoculated with varying volumes (1; 2; 3; 4; and 5 mL) and incubated statically for different periods (3; 6; 9; 12; and 18 days), using a full factorial experimental design. Thickness, uniformity, weight, and yield were evaluated. In the optimization study, a Box–Behnken design was used. Two independent variables were used: inoculum volume (X1: 1; 3; and 5 mL) and fermentation period (X2: 6; 12; and 18 d) to determine the target response variables: thickness, swelling ratio, drug release, fiber diameter, Tensile strength, and Young's Modulus for both dry and moist BC membranes. The mathematical modelling of the effect of the 2 independent variables was accomplished by response surface methodology (RSM). The obtained models were validated with new experimental values, and confirmed for all tested properties, except Young Modulus of oven-dried BC. Thus, the optimal properties in terms of a scaffold material of the moist BC were obtained with an inoculum volume of 5% (v/v) and 16 d of fermentation. While, for the oven-dried membranes a 4% (v/v) and 14 d of fermentation.
Klasifikasi Status Desa/Kelurahan DIY (Yogyakarta) Menggunakan Model Decision Tree (Studi Kasus Data Praktik Kerja Lapangan Politeknik Statistika STIS Tahun 2020)
Authors: Mahmud Apriliansyah , Pangestika Ana , Ramadhanty Annisa Putri , Putra Galang Madya , Putri Galuh Sri Natungga Dewi Susilo , Nooraeni Rani 
Published: February 2021

Status desa/kelurahan menjadi sebuah hal yang penting guna mengetahui perkembangan pembangunan yang ada pada desa/kelurahan tersebut serta dalam melakukan evaluasi terkait kebijakan yang telah dibuat mengenai infrastruktur. Badan Pusat Statistik (BPS) telah melakukan proses klasifikasi dengan metode skoring. Oleh karena itu pada penelitian ini akan mengimplementasikan model decision tree dikarenakan indicator klasifikasi status desa/kalurahan yang digunakan BPS belum mengikuti perkembangan zaman. Dalam penelitian ini menggunakan data hasil Praktik Kerja Lapangan (PKL) Politeknik Statistika STIS tahun 2020 yang dilaksanakan di D.I.Yogyakarta. Diharapkan penelitian ini dapat menjadi metode alternatif untuk mengganti metode yang sudah ada. Hasil penelitian menunjukkan bahwa dari 438 desa/kelurahan model decision tree mampu mengklasifikasi secara benar 392 desa/kelurahan sesuai dengan status desa/kelurahan sebelumnya. Model ini memiliki tingkat kebaikan model (specificity) sebesar 90.32%, presisi model (precision) sebesar 87.5%, sensitivitas model (recall) sebesar 88.42%, serta F1 Score
sebesar 87.95%.
Optimal water allocation of the Zayandeh-Roud Reservoir in Iran based on inflow projection under climate change scenarios
Authors: Saedi Fatemeh , Ahmadi Azadeh , Abbaspour Karim C. 
Published: February 2021

Abstract
The impact of climate change on water availability has become a significant cause for concern in the Zayandeh-Roud Reservoir in Iran and similar reservoirs in arid regions. This study investigates the climate change impact on water supply and availability in the Zayandeh-Roud River Basin. For better management, the Soil & Water Assessment Tool (SWAT) was used to develop a hydrologic model of the basin. The model was then calibrated and validated for two upstream stations using the Sequential Uncertainty Fitting (SUFI-2) algorithm in the SWAT-CUP software. The impact of climate change was modeled by using data derived from five Inter-Sectoral Impact Model Intercomparison Project general circulation models under four Representative Concentration Pathways (RCPs). For calibration (1991–2008), the Nash–Sutcliffe efficiency (NSE) values of 0.75 and 0.61 at the Ghaleshahrokh and Eskandari stations were obtained, respectively. For validation (2009–2015), the NSE values were 0.80 and 0.82, respectively. The reservoir inflow would probably reduce by 40–50% during the period of 2020–2045 relative to the base period of 1981–2006. To evaluate the reservoir's future performance, a nonlinear optimization model was used to minimize water deficits. The highest annual water deficit would likely be around 847 MCM. The lowest reservoir reliability and the highest vulnerability occurred under the extreme RCP8.5 pathway.
Multi-model ensemble projection of mean and extreme streamflow of Brahmaputra River Basin under the impact of climate change
Authors: Alam Sarfaraz , Ali Md. Mostafa , Rahaman Ahmmed Zulfiqar , Islam Zahidul 
Published: February 2021

Abstract
The streamflow of Brahmaputra River Basin is vital for sustainable socioeconomic development of the Ganges delta. Frequent floods and droughts in the past decades indicate the susceptibility of the region to climate variability. Although there are multiple studies investigating the basin's future water availability, most of those are based on limited climate change scenarios despite the wide range of uncertainties in different climate model projections. This study aims to provide a better estimation of projected future streamflow for a combination of 18 climate change scenarios. We develop a hydrologic model of the basin and simulate the future water availability based on these climate change scenarios. Our results show that the simulated mean annual, mean seasonal and annual maximum streamflow of the basin is expected to increase in future. By the end of the 21st century, the projected increase in mean annual, mean dry season, mean wet season, and annual maximum streamflow is about 25, 178, 11, and 22%, respectively. We also demonstrate that this projected streamflow can be expressed as a multivariate linear regression of projected changes in temperature and precipitation in the basin and would be very useful for policy makers to make informed decision regarding climate change adaptation.
Effective treatment of the wastewater from ceramic industry using ceramic membranes
Authors: Shurygin Maxim , Guenther Christiane , Fuchs Stephan , Prehn Volker 
Published: February 2021

Abstract
Emissions of organic compounds, heavy metals and chemicals used in the ceramic industry cause significant organic and inorganic pollution of water. The effluent must be treated before it is discharged into a water body. International and EU laws control the chemical oxygen demand (COD) of the wastewater. Conventional technologies, such as sedimentation, flocculation and biological treatment, have lots of drawbacks, whereas membrane technologies give many benefits, as they are chemical-free and allow a reduction of the treatment steps. One-step wastewater nanofiltration with ceramic membranes of 450 Da cut-off is able to reduce the COD of ceramic wastewater to a sufficient level. However, the working time without cleaning is limited and the rejection of membranes can be significantly reduced due to fouling. Multistage filtration can be the solution. Filtration experiments with various combinations (MF, UF and NF) of ceramic membranes were performed at a laboratory scale with single-channel membranes and at pilot scale with 7-, 19- and 151-channel membranes in order to permanently reach the limit value of a COD below 80 mg/L and to increase the operating time. Four types of membranes were sequentially tested in the cross-flow mode: MF (200 nm pore size), UF (2,000 Da), NF (450 Da) and NF (200 Da). 5-day Biological Oxygen Demand (BOD) tests were performed in order to examine the wastewater biodegradability. The test results with single-channel membranes showed that in terms of the highest COD rejection and the highest permeability, the best combination was that of MF and UF membranes. Here, UF membranes were sufficient to reach the limit values. As for the multi-channel membranes, the combination of MF and NF (450 Da) was the best and the final COD concentration ranged from 11 to 48 mg/L. 5-day BOD bottle tests showed a COD/BOD ratio of 3.8, which opened up possibilities for combined treatment.
Anthropological Aspects of Problem Of God, Faith and Grace
Authors: Ozorowski Edward 
Published: February 2021

e arguments presented here can be qualified as a part of the more extensiveproblem concerning relations between the Christian religion and human nature.We have only limited ourselves to paying attention to the essential componentsof the religious phenomenon&Y. It seems, however, that in the context of all thesetheological theses and church rites, the question should be posed about howthey arise from human existence as well as how they can serve it since only thenwould their fully anthropological value be fully manifested. What is more, oneshould refer to a religious phenomenon as such and consider Christianity in itscontext. Christian religion, in spite of its essential separateness from other religions,shares many common features with them. Christians, therefore considerimportant the philosophical question of whether religiousness defines man to thesame extent as the category homo sapiens, homo socialis, homo faber, etc. does&_.e problem of the role that religion plays in human life is also significant. Manyscholars, for example, emphasize the personality-forming role of religion andits role in maintaining man’s mental health;`.Man is then the point of reference when proving the raison d’être of theChristian religion. It is not enough to say that the Church comes from God, wemust also justify that it is necessary for people.Similarly, the problem of verification of the Christian religion does notonly consist in proving that the present-day Church comes from Christ and thatin its historical duration it remains faithful to the will of its founder, but alsoin justification of the thesis that it represents the value necessary for people.
Since according to the scholastic principle of verum, it can be considered ensand bonum at the same time. e latter is, however, an anthropological issue.Also dogmatic and moral theology, not to mention practical theology andtheology of internal life, which by their very nature deal with man, is characterizedby an anthropological attitude. We have already mentioned that contemporaryCatholic theology is strongly inclined towards anthropology. It must beadded here that the interests of dogmatics and moral theologians should not belimited to the mere interpretation of revealed truths about man, but should alsotake into account the confrontation of these truths with the experience of a manabout himself. en the relevance and validity of dogmatic theorems will becomeclearer and indications of moral theology will become more convincing.
Implementing a Peer Advocate Mental Health Digital Intervention Program for Ohio Youth: Descriptive Pilot Study
Authors: Albritton Tashuna , Ford Kelsey Lynett , Elsbernd Kira , Santodomingo Melodie , Juzang Ivan , Weddington Pam , Bull Sheana 
Published: February 2021

Background
In the United States, millions of adolescents report poor mental health, where 1 in 5 teenagers considers suicide. Reducing stigma and fostering peer support remains critical for positive mental health interventions and programs. Increasingly, digital mental health tools have emerged with great promise, leveraging social networks. Despite the potential, limited understanding of such comprehensive programs and their implementation exist.

Objective
The objective of this study investigates a piloted digital mental health training program (Be Present) for youth, specifically describing the impact on youth behavioral outcomes and user engagement and identifying high-risk youth in the early phases of prevention.

Methods
Eligibility included Ohio residents (aged 14 to 22 years) to be enrolled as either a Friend or a Peer Advocate. From May 1 to June 1, 2019, participants completed the Advocate training course, taking pretest and posttest surveys. Single-arm descriptive analyses measured youth outcomes (self-efficacy, intentions, behaviors, social support, knowledge, and sources of strength) and engagement and assessed risk based on survey responses.

Results
A total of 65 adolescents participated, with 54 completing both pretest and posttest surveys. The majority of participants included non-Hispanic White females. Findings illustrated a significant increase in self-report of referrals for mental health services as well as in perceptions that youth had of experiencing social support; however, no significant differences were found for measures of self-efficacy, knowledge, and sources of strength between pretest and posttest surveys. Roughly two-thirds of the participants completed all of the Advocate training modules, and we observed a gradual decline in engagement. Most respondents who received escalated high-risk response messages identified as female.

Conclusions
The pilot presented promise for implementing a digital mental health program focused on peer support, specifically observing reported youth behavioral outcomes and user engagement and identifying high-risk youth. Various limitations exist given the small nonrepresentative sample and lack of control group. All findings should be considered preliminary to a larger trial and underscore the feasibility of delivering online training programs to bolster adolescent mental health. Such formative evaluation proved critical for future implementation and research, offering opportunity for substantial improvements for real-world digital mental health programs.
The prognostic impact of renal function decline during hospitalization for myocardial infarction
Authors: Mayer Otto , Seidlerová Jitka , Bruthans Jan , Opatrný Jan , Hromádka Milan , Jirák Josef , Filipovský Jan 
Published: February 2021

Aim:
We analyzed the mortality risk of myocardial infarction (MI) patients according to renal function, observed during hospitalization.
Materials & methods:
Patients hospitalized for MI between 2006 and 2018 were followed (n = 5659). We divided the sample into four groups by estimated glomerular filtration (eGFR) [ml/min]: normal functions (lowest eGFR during hospitalization >60); transiently moderate insufficiency (lowest eGFR >30 and ≤60, highest >60); permanently moderate insufficiency (highest eGFR >30 and ≤60); severe insufficiency (highest and lowest eGFR ≤30).
Results:
Permanently moderate renal insufficiency indicates increased 5-years all-cause mortality (hazard risk ratio: 2.27 [95% CIs: 1.87–2.75], p < 0.0001), but a similar risk was found in patients with the only transient decline of renal functions (hazard risk ratio: 2.08 [95% CIs: 1.70–2.55], p < 0.0001). Both moderate insufficiency subgroups (transient/permanent) did not statistically differ regarding mortality risk.
Conclusion:
Even just fluctuation of eGFR toward moderate insufficiency during hospitalization represents an important prognostic indicator in MI patients.
Strategies to improve the availability of medicines in primary health care in Brazil: findings and implications
Authors: Barbosa Mariana M , Nascimento Renata CRM , Garcia Marina M , Acurcio Francisco A , Godman Brian , Guerra Augusto A , Alvares-Teodoro Juliana 
Published: February 2021

Aim:
Access to essential medicines is a key component of managing patients in ambulatory care. In 2008, the State of Minas Gerais, Brazil, created the Pharmacy Network of Minas (Rede Farmácia de Minas [RFM]) program to improve access to medicines, increasing availability and restructuring the infrastructures. The aim was to assess the current situation, comparing municipalities with and without RFM.
Materials & methods:
Descriptive survey study, data collected from 2014 July to May 2015. Availability was verified by stock levels.
Results:
The drug availability index was 61.0%, higher in municipalities with RFM. Most physicians considered the pharmaceutical services as good/very good. The main reasons for medicines shortage were ‘financial transference problems’, ‘insufficient financial resources’ and ‘budget’.
Conclusion:
Strategies, such as the RFM can promote improvements in medicine availability.
Heterogeneity in renal end points of cardiovascular outcomes trials in Type 2 diabetes
Authors: Balijepalli Chakrapani , Yan Kevin , Zoratti Michael , Franklin Meg , Druyts Eric 
Published: February 2021

Composite renal end points and end stage renal disease (ESRD) are frequently included as prespecified secondary end points in the cardiovascular outcomes trials (CVOTs) of diabetes medications. We examined the heterogeneity in the definitions of composite renal end point and ESRD in CVOTs. Five criteria (macroalbuminuria, doubling of serum creatinine, estimated glomerular filtration rate [GFR], ESRD and renal death), were considered for the renal composite end point across the trials. Only three of the 12 trials included all five criteria, whereas the other trials included different combinations of four, three and two criteria. ESRD definition also showed considerable heterogeneity across the trials. Heterogeneity exists in the definitions of renal composite and ESRD end points in CVOTs making it challenging to assess comparative efficacy of the active treatments for reimbursement purposes.
Medication review with follow-up for cardiovascular outcomes: a trial based cost–utility analysis
Authors: Ahumada-Canale Antonio , Vargas Constanza , Balmaceda Carlos , Martinez-Mardones Francisco , Plaza-Plaza José Cristian , Benrimoj Shalom , Garcia-Cardenas Victoria 
Published: February 2021

Aim:
To assess the trial-based cost–effectiveness of medication review with follow-up compared with usual care in primary care.
Materials & methods:
A cluster randomized controlled trial included patients if they were independent older adults, receiving five or more prescriptions, with moderate or high cardiovascular risk. Costs were estimated from the public healthcare sector perspective, and health benefits were measured as quality-adjusted life years. Both of which were used to calculate the incremental cost–effectiveness ratio.
Results:
Twelve centers completed the study, six (146 patients) in the intervention group and six (145 patients) in the control group. The base-case analysis showed an incremental cost–effectiveness ratio of US$ (2019) 434.4/quality-adjusted life year (95% CI 64.20–996.03).
Conclusion:
The intervention was cost-effective in the public primary care setting.
Purchase Order “Analytic Audit”
Authors: O'Leary Daniel E. 
Published: February 2021

ABSTRACT
This paper reviews a case study used as part of introducing data and analytics in a Masters of Accounting curriculum. In particular, this paper presents a dataset, an approach to analyzing that data using analytic approaches, suggests that analysis of that dataset could function as a capstone project, and provides a review of multiple data, analytical tools, and methodologies. The dataset includes almost 13,500 purchase orders and allows the use of multiple data analytic approaches for anomaly detection, time-series analysis, and visualization to meet audit goals such as identification of unusual or significant items, determination of trends, and concentration of purchasing activity.
Can Employees Exercise Control Over Managers? The Role of the Employees' Knowledge of Manager Behavior and Manager Discretion
Authors: Yin Huaxiang 
Published: February 2021

ABSTRACT
I investigate whether organizations can use the “power of the employee” to reduce managers' opportunistic behavior toward others. I predict that revealing this behavior to employees makes managers less inclined to act opportunistically. Employees' knowledge has a stronger impact on reducing managers' opportunistic behavior when managers have discretion over employee rewards versus when they do not. I further predict that the effect of employee-based control depends on whether managers are other-interested versus self-interested. Revealing manager actions alone is sufficient to reduce other-interested managers' opportunism, even when they lack discretion over employee rewards. Revealing manager actions alone has no discernible influence on self-interested managers' opportunism, but pairing this action with granting them discretion over employee compensation does reduce their opportunism. Results of two experiments support my predictions, and these results have important implications. By relying on the power of the employee, organizations can induce (even selfish) managers to act less opportunistically.
JEL Classifications: C91; D83; M40.
Deterrent Disclosure
Authors: Glaeser Stephen A. , Landsman Wayne R. 
Published: February 2021

ABSTRACT
We examine how product market competition affects the disclosure of innovation. Theory posits that product market competition can cause firms to increase their disclosure of innovation to deter product market competitors. Consistent with this reasoning, we find that patent applicants in more competitive industries voluntarily accelerate their patent disclosures, which are credibly disclosed via the United States Patent and Trademark Office. Our inferences are robust to using changes in industry-level import tariffs as sources of plausibly exogenous variation in product market competition in difference-in-differences designs. Consistent with patent disclosure deterring product market competitors, we find that timelier patent disclosures are more strongly associated with declines in the similarity of competitors' products than are less timely patent disclosures. In total, our results suggest that product market competition increases patent disclosure timeliness, which is consistent with firms using the disclosure of innovation to deter product market competition.
JEL Classifications: D23; G38; O30; O31; O33; O34; O38.
"A Perfect Work of Art". A propósito de las primeras traducciones al inglés de «Pepita Jiménez»
Authors: Ramos García Ana María María , Sánchez García Remedios 
Published: February 2021

En el presente artículo se hace un análisis de las primeras traducciones y adaptaciones al inglés de Pepita Jiménez, la obra principal del escritor decimonónico Juan Valera y una de las novelas costumbristas más destacadas del siglo XIX. Se realiza un análisis del proceso de traducción, tanto de las ediciones americanas como de la británica, estudiando las similitudes y diferencias en cuanto al diseño y estructura de la obra que, en ese tiempo estuvieron supervisadas por el autor, uno de los primeros novelistas españoles en negociar su proyección en el potente mercado editorial de los países anglófonos.