bluuebunny/crossref_metadata_2025_split huggingface dataset:
Το παιχνίδι ρόλων και οι επιδράσεις του σε μάθημα προγραμματισμού υπολογιστών πρώτου εξαμήνου
Authors: Σπανουδάκης Νικόλαος , Κρασαδάκη Ευαγγελία 
Published: January 2025

Το άρθρο παρουσιάζει την πιλοτική εφαρμογή ανάθεσης ρόλων σε μέλη ομαδικών εργασιών για την ανάπτυξη μιας εφαρμογής λογισμικού σε μάθημα πρώτου εξαμήνου, το οποίο προσφέρεται σε σχολή μηχανικών που δεν θεραπεύει την επιστήμη και τεχνολογία υπολογιστών. Το μάθημα εφαρμογής είναι η Μεθοδολογία Προγραμματισμού Υπολογιστών της Σχολής Μηχανικών Παραγωγής και Διοίκησης του Πολυτεχνείου Κρήτης, όπου οι πρωτοετείς έχουν χαμηλή συμμετοχή στις εξετάσεις, παρά την συμμετοχή τους στις διαλέξεις και τα εργαστήρια. Προκειμένου να ενισχυθεί η αυτοπεποίθησή τους και να δοθούν επιπλέον ευκαιρίες μάθησης, ο διδάσκων εισήγαγε τον συνδυασμό των δύο εκπαιδευτικών τεχνικών, ως μία έξτρα δυνατότητα. Οι ομάδες συγκροτήθηκαν από τέσσερα έως πέντε άτομα, ενώ οι ρόλοι που ανατέθηκαν είναι του Συντονιστή, του Αναλυτή, των Προγραμματιστών (δύο άτομα) και του Ελεγκτή. Τα αποτελέσματα έδειξαν τη θετική σχέση μεταξύ της ομαδικής εργασίας με ρόλους και της συμμετοχής στις εξετάσεις, ενώ επιβεβαιώθηκε η διαφορά στάσεων σε σχέση με το φύλο στα μαθήματα προγραμματισμού. Επιπλέον, η ανάλυση της μαθησιακής εμπειρίας με αξιοποίηση του μοντέλου Kano, έδωσε σημαντικές πληροφορίες στον διδάσκοντα για το τι θεωρούν οι φοιτητές/τριες επιθυμητά ή ελκυστικά ή αδιάφορα χαρακτηριστικά του σχεδιασμού του μαθήματος. Αν και η ταξινόμηση των περισσοτέρων χαρακτηριστικών ως επιθυμητής ποιότητας ήταν λίγο-πολύ αναμενόμενη, η ταξινόμηση ορισμένων ως ελκυστικής ή αδιάφορης ποιότητας αποτέλεσε μια πολύτιμη ανατροφοδότηση.
Βιβλιοπαρουσίαση: Γρηγοριάδης, Α., Τσιτιρίδου-Ευαγγέλου, Μ., & Κρουσοράτη, Α. (2023). "Οικογενειακό μαθησιακό περιβάλλον: Θεωρητικές προσεγγίσεις, μέτρηση ποιότητας και καλές πρακτικές". Σοφία.
Authors: Μανωλίτσης Γεώργιος 
Published: January 2025

Το βιβλίο "Οικογενειακό μαθησιακό περιβάλλον: Θεωρητικές προσεγγίσεις, μέτρηση ποιότητας και καλές πρακτικές" αποτελεί μία ολοκληρωμένη πρόταση προσέγγισης της έννοιας του οικογενειακού μαθησιακού περιβάλλοντος (home learning environment). Μέσα από θεωρητικές και ερευνητικές προσεγγίσεις αναδεικνύεται η καίρια αξία και η σπουδαιότητά του για την ολόπλευρη ανάπτυξη των παιδιών, ενώ ταυτόχρονα προτείνονται πρακτικοί τρόποι υποστήριξης και ενδυνάμωσής του. Μέσα στην παρούσα βιβλιοπαρουσίαση παρατίθενται συνοπτικά οι διαστάσεις με τις οποίες εμπλέκεται το βιβλίο για την μελέτη του οικογενειακού μαθησιακού περιβάλλοντος σε καθένα από τα εννέα κεφάλαιά του καθώς και την πρόταση των συγγραφέων για μία νέα προσέγγιση του ζητήματος αυτού, την οποία αποκαλούν ως "Οικογενειακό Μαθησιακό Οικοσύστημα".
Identifying the eminent indicators and criteria of Sustainability Assessment Tools in Higher Education: a systematic literature review.
Authors: Xenaki Maria , Dimou Irini , Passas Ioannis 
Published: January 2025

The significance of incorporating sustainability in (tourism) higher education is beyond doubt. This article aims to assess how this integration is best measured. This objective considers two variables: A. the indicators, referring to the questions being asked to investigate the nature of sustainability integration, and B. the criteria, referring to the organisational aspect or level at which the institute integrates sustainability. Hence, the emerging questions are: 1) What is the most appropriate set of questions that best assess sustainability integration in a Higher Education Institution? (indicators) And 2) To what department, operation, or process should this question be addressed? (criteria). The feature of the significance of the most important indicators and criteria becomes evident through the frequency of repetition. A systematic literature review regarding the sustainability assessment tools (SAT) in higher education is conducted, following PRISMA guidelines.
From Interviews to Interpretation: Utilizing Delphi Method to Assess Content Validity of Sports Event Factors and their Impact on Extending the Tourism Season in Greece
Authors: Gkarane Sofia K. , Vassiliadis Chris A. , Fragidis Garyfallos , Kotzaivazoglou Iordanis , Vrana Vasiliki 
Published: January 2025

Running tourism is regarded as one of the most rapidly growing sectors within the sport tourism industry worldwide. This is particularly true in Greece, where running events have increased in popularity. The specific objectives of this study were to assess the content validity of the key factors that influence the organizational process of sporting events, particularly running events, from the perspectives of Greek running event organizers within the framework of sustainable sport event tourism. This study uses the Delphi method to explore how these experts interpret feedback on factors influencing sport event organization in low-season period.

The Delphi process yielded a comprehensive list of factors influencing the organizational process of sporting events during the low-season period, categorized into enhancements (focused on attracting participants to stay longer through enriched experiences) and success pillars (focused on the foundations of building trust for a well-organized event in low-season period).

The findings of the current study provide valuable perspectives into how sports event experts interpret feedback, particularly regarding extending the tourism season through sport events. The identified factors and the experts' perspectives offer a comprehensive framework for understanding the specific feedback needs of sports event experts in this context.
Impact of the EU regulations on the payment services
Authors: Korus Krzysztof 
Published: January 2025

Abstract

Motivation: Legislation in payment services domain is broad, exhaustive, and detailed. Fostering innovation is one of several primary goals of the legislation. The impact of a series of regulations on the payments market, particularly the Second Payment Services Directive (PSD2), requires a comprehensive assessment of their effects on legislative efficiency and the development of European payment service providers.

Aim: The paper aims to explore the vectors and strength of the impact of EU payments legislation on the market for payment services with a focus on innovation.

Results: The major impact vector of the payment legislation is stimulating the supply of payment services. An important instrument in this domain is standardization and interoperability with legislation on open banking (PSD) and Single Euro Payment Area being flagship use – cases of such instrument. Open banking legislation (standardization) resulted in the development of a new class of services unlocking new value for demand side. SEPA legislation (interoperability) resulted in availability of significantly more efficient and productive flows of funds within the EU. In both use – cases the impact vectors demonstrate strong feedback and positive reinforcement. Instant payments developed on the building blocks of SEPA enable open banking account – to - account payments to compete with payment cards and similar instruments with acquirers being able to narrow down substantially the risks they are exposed to when engaging in traditional merchant payments. Open banking payments in turn stimulate SEPA payments. Altogether the use case of EU SEPA and open banking legislation proves that legislation addressing interoperability and standardization is paramount to steer payment market towards mutually reinforced innovation. Careful consideration and selection of policy mix in this domain results in highly efficient transmission mechanism.
Treatment options of human demodicosis
Authors: Pawełczyk Olga 
Published: January 2025

Background: Human demodicosis is a parasitic disease caused by two species of mites, Demodex folliculorum and Demodex brevis. Cutaneous and ocular demodicosis most often occurs in a situation of impaired immune response, where the attacked organism is weakened, has reduced immunity or metabolic disorders. The treatment of demodicosis can last up to several months and requires a lot of patience and regularity from the patient.
Objective: The aim of this paper is to review the therapeutic options used in the treatment of the ocular and cutaneous human demodicosis.
Materials and methods: This review was based on available data collected in the PubMed and Google Scholar databases, using the keywords: ‘Demodex brevis’, ‘Demodex folliculorum’, ‘Demodex mite’, ‘human demodicosis treatment’.
Conclusions: Treatment of demodicosis based on the use of a single medicament has the lowest efficiency and effectiveness. In contrast, a combination therapies, in which oral and local applied medication are taken together or several types of local medication are combined have the best effect.
Dropping the baton: Cognitive biases in emergency physicians
Authors: Ng Mingwei , Wong Evelyn , Sim Guek Gwee , Heng Pek Jen , Terry Gareth , Yann Foo Yang 
Published: January 2025

Introduction
Clinical medicine is becoming more complex and increasingly requires a team-based approach to deliver healthcare needs. This dispersion of cognitive reasoning across individuals, teams and systems (termed “distributed cognition”) means that our understanding of cognitive biases and errors must expand beyond traditional “in-the-head” individual mental models and focus on a broader “out-in-the-world” context instead. To our knowledge, no qualitative studies thus far have examined cognitive biases in clinical settings from a team-based sociocultural perspective. Our study therefore seeks to explore how cognitive biases and errors among emergency physicians (EPs) arise due to sociocultural influences and lapses in team cognition.

Methodology
Our study team comprised four EPs of different seniorities from three different institutions and local and international academics who provided qualitative methodological guidance. We adopted a constructivist paradigm and employed a reflexive thematic analysis approach which acknowledged our researcher reflexivity. We conducted seven focus group discussions with 25 EPs who were purposively sampled for maximum variation. Our research question was: How do sociocultural factors lead to cognitive biases and medical errors among EPs?

Results
Our themes coalesce around sociocultural pressures related to team psychology. In theme one, the EP is compelled by sociocultural pressures to blindly trust colleagues. In the second, the EP is obliged by cultural norms to be “nice” and neatly summarise cases into illness scripts during handovers. In the last, the EP is under immense pressure to follow conventional wisdom, comply with clinical protocols and not challenge inpatient specialists.

Conclusion
Cognitive biases and errors in clinical decision-making can arise due to lapses in distributed team cognition. Although this study focuses on emergency medicine, these pitfalls in team-based cognition are relevant across the entire continuum of care and across all specialties of medicine. The hyperacute nature of emergency medicine merely exacerbates and condenses these into a compressed timeframe. Indeed, similar relays are run every day in every discipline of medicine, with the same unified goal of doing the best for our patients while not committing cognitive errors and dropping the baton.
O metodách a cílech terénního výzkumu jazyka a kultury
Authors: Zima Petr 
Published: January 2025

1. Although traditionally links between methods of field research of languages and cultures have been emphasised and in the approach of some American descriptive schools the research of language and culture was even made part of a joint methodological framework of anthropology, there are also undoubtedly some basic differences. 2. Biological and cultural criteria are perhaps too much stressed in the question of the choice of the informants in traditional works about the problems of field research; one has to stress here the diversity of the criteria with which informant are selected in the field research of language and culture. While research of culture requires a measure of orientation and experience (which implies a higher age and proportion of the years spent in a given community for the people under examination), good information can also be provided for the research of language also by a psychologically and physically orientated very young man (a student). By contrast, older people under examination dosely linked with a culture and some habits can become under certain circumstances an obstacle to objective research of a neutral register of a given variety/language because instead of it they force field researchers to accept a functionally biased specific register of culturally bound texts (such as oral literature). 3. The choice of the type of texts is also vital: most traditional texts providing relevant information about culture are monologic accounts. A picture arisen from the analysis of such texts does not cover neutral expressions in a given code, especially in the sphere of syntax. From the linguistic viewpoint one has to confront such monologic texts with neutral dialogues on day-to-day themes (which, in their turn, have a smaller value in terms of research of culture). 4. The field research of culture and language cannot be entirely separated in the sphere of analysis in view of their natural communication links. Instead, one always has to bear in mind which priorities within the framework of a given research are really of primary importance and which are only registered for further use by a different discipline.
Reference intervals of hematological parameters in the Chilean adult population and the Mapuche ethnic group
Authors: Letelier Pablo J. , Chicahual Carolina A. , Arroyo Nicolas F. , Monsalves Daniel P. , Boguen Rodrigo E. , Guzmán Neftalí H. 
Published: January 2025

Abstract

Objectives
Reference intervals (RI) are an essential tool to support clinical decisions. These may have intra- and inter-individual variations associated with genetic differences and environmental factors. Given that Chile is a multiethnic territory, studying these variables is even more relevant. The purpose of this study was to establish RI for various hematological parameters in the Chilean population and the Mapuche ethnic group.

Methods
A sample of 356 adult individuals (aged 18–65 years), of which 146 belonged to the Mapuche ethnic group, was selected using the indirect a posteriori method from the database of the UC Temuco Clinical Laboratory. The analysis was conducted by sex and ethnicity. The Tukey fences method was employed to detect outliers, and the RIs were established through the non-parametric method recommended by the IFCC.

Results
The median age for the overall sample of the general population was 35 years (female) and 36 years (male). Differences (p<0.05) were found by sex in parameters dependent on hemoglobin and platelets counts. In the analysis by ethnicity, the parameters of RBC, HGB and HCT presented significant differences (p<0.0001).

Conclusions
This study shows that hematological RI vary according to sex and ethnicity, which must be considered in a multiethnic population. This understanding enhances our comprehension of the individual characteristics of each person and facilitates more accurate clinical interpretation.
MFAP5 inhibits the malignant progression of endometrial cancer cells in vitro
Authors: Liang Guanying , Qi Zijuan , Du Chun 
Published: January 2025

Abstract
To investigate the biological role of MFAP5 in endometrial cancer (EC). HEC-1-A and Ishikawa cells overexpressing MFAP5 were created. Cell proliferation, apoptosis, migration, and invasion were evaluated using CCK8, colony formation, flow cytometry, and transwell assays. A western blot was used to analyze the expression of markers affiliated with the epithelial–mesenchymal transition process and AKT/mTOR pathway. As a result, MFAP5 was found to be down-regulated in EC. Overexpression of MFAP5 suppressed proliferation and promoted apoptosis of HEC-1-A and Ishikawa cells, as evidenced by the inhibition of cell viability and colony formation, and the increase in cell apoptosis rate. Besides, overexpression of MFAP5 attenuated the abilities of cell migration and invasion, as well as reduced MMP2 and MMP9 protein expression. Furthermore, E-cadherin protein level was elevated, while N-cadherin and α-SMA protein levels were decreased, and the phosphorylation of AKT and mTOR was reduced in cells overexpressing MFAP5. Our findings indicate that MFAP5 overexpression inhibits the malignant behaviors of EC cells, possibly by blocking the AKT/mTOR pathway, suggesting that MFAP5 may be a new therapeutic target for EC.
Major ozonated autohemotherapy promoted functional recovery following spinal cord injury in adult rats via the inhibition of oxidative stress and inflammation
Authors: Xia Liwei , Sun Yongming , Zhou Yue , Yang Qian , Huang Jianhan , Liu Dong 
Published: January 2025

Abstract
This study sought to explore the value of major ozonated autohemotherapy (MOA) as a treatment for spinal cord injury (SCI) in a rat model system. In total, 54 female Sprague-Dawley rats were randomized into sham-operated, SCI model, and MOA treatment groups. We found that relative to the SCI model group, rats that underwent MOA treatment exhibited improved locomotor scores on days 14, 21, and 28 after injury (p < 0.05) together with reduced residual urine on days 5, 7, 14, and 21 after injury (p < 0.05). MOA treatment also lowered proinflammatory TNF-α, IL-1α, and C1q levels on day 3 post-injury (p < 0.05), decreased malondialdehyde levels, and enhanced superoxide dismutase activity (p < 0.001). Activated astrocytes in MOA-treated rats exhibited larger soma and higher levels of extracellular matrix secretion, whereas reactive microglia in the MOA group presented with a ramified morphology in contrast to the amoeboid morphology exhibited by these cells in SCI model rats. MOA offers potential value as a means of protecting spinal cord integrity, potentially through anti-inflammatory, antioxidant, and regulatory effects that shape the polarization of astrocytes and microglia.
Differential expression of phosphoinositide 3-kinase/protein kinase B and Toll-like receptor/nuclear factor kappa B signaling pathways in experimental obesity Wistar rat model
Authors: Song Liya , Li Lihua 
Published: January 2025

Abstract
This study aimed to investigate the differential expression of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) signaling pathway in relation to the Toll-like receptor (TLR)/nuclear factor κB (NF-κB) signaling pathway in an obese rat model. A total of 200 8-week-old male Wistar rats were randomly assigned to a control group (Ctrl, n = 40) and an observation group (Obs, n = 160), with obesity induced through a high-fat diet. Following modeling, the Obs group was further divided into a model group, a PI3K/AKT inhibition group, a TLR/NF-κB inhibition group, and a combined PI3K/AKT + TLR/NF-κB inhibition group, with 40 rats in each. Metabolic changes were assessed by monitoring the glucose infusion rate (GIR), as well as conducting an intraperitoneal glucose tolerance test (IPGTT) and an intraperitoneal insulin tolerance test (IPITT). Hematoxylin and eosin staining was utilized to observe morphological changes in adipose tissue, while Western blotting was employed to detect the expression levels of proteins associated with the PI3K/AKT and TLR/NF-κB signaling pathways in adipose tissue. The results indicated that the Obs group exhibited significantly higher blood glucose and insulin levels during the IPGTT and IPITT experiments compared to the Ctrl group (P < 0.05). Additionally, the GIR, as well as the expression levels of p-PI3K and p-AKT proteins in the Obs group, were significantly lower than those in the Ctrl group (P < 0.05). In both the PI3K/AKT inhibition group and the combined PI3K/AKT + TLR/NF-κB inhibition group, the expression of relevant proteins further declined (P < 0.05). These findings suggest that while a high-fat diet decreases the activity of the PI3K/AKT signaling pathway, it concurrently promotes inflammatory responses by upregulating the TLR-4 and NF-κB signaling pathways, indicating a critical role for these pathways in obesity-related metabolic abnormalities.
Guaranteed Income: A Policy Landscape Review of 105 Programs in the United States
Authors: Rodriguez Sarina , Kagawa Rose , Koundinya Vikram , Choe Daniel , Vaitla Bapu , Volzer Alyx , Brinkley Catherine 
Published: January 2025

Abstract
Cash assistance programs have been piloted as Basic or Guaranteed Income across the United States. This research asks how programs are being designed and evaluated, with implications for how collective program impacts are understood. To answer this question, we assemble and review 105 programs based in the United States, covering over 40,000 beneficiaries. We compare eligibility criteria, funding sources, distribution amounts, program administration, pilot duration, and evaluation measures. We find that just over half of the programs use income-based qualifications and most (84 %) have some form of place-based eligibility criteria defined by residence. The plurality of programs (28) are based in California (CA) and 16 operate at the county level. We also find that while the development of pilots often uses community development framing, funding and evaluation measures tend to be more aligned with either economic or public health intervention assessments. As multiple fields of study engage with poverty alleviation, our findings add nuance to the complex and continuously developing landscape of interventions and evaluations.
Quality indicators for urine sample contamination: can squamous epithelial cells and bacteria count be used to identify properly collected samples?
Authors: Walber Gabriela Blauth , Poloni José Antonio Tesser , Rotta Liane Nanci 
Published: January 2025

Abstract

Objectives
To evaluate urinalysis parameters useful for identifying mixed cultures in urine culture using an automated urinary particle analyzer to assess quality indicators (QIs) for urine sample contamination.

Methods
A retrospective observational cross-sectional study was conducted with 2,527 urine samples from patients of a quaternary hospital in Brazil. Urine samples were processed simultaneously in Sysmex UF-5000 flow cytometry analyzer (urinalysis) and MALDI-TOF (culture).

Results
For all samples, a cutoff of 123.8 bacteria/µL was established to discriminate culture-negative specimens. ROC curve indicated the following cutoffs for females and males, respectively: 193.65 and 23.55 bacteria/µL, and 21.35 and 5.05 squamous epithelial cells (SEC)/µL, with the latter two related to scenarios of sample contamination/colonization through mixed cultures. Performing univariate logistic regression, we found a 2.78 (CI95 %: 2.12–3.65) times higher chance of probable mixed culture when SEC values were above the cutoffs for each sex, and 6.91(CI95 %: 4.56–10.47) times for bacteria. For multivariate logistic regression, the OR values were 1.62 (CI95 %: 1.21–2.15) and 5.82 (CI95 %: 3.77–8.98), respectively.

Conclusions
The fluorescent flow cytometry analyzers could efficiently identify urinary bacteria counts associated with contamination/colonization scenarios using the cutoffs of 21.35 SEC/µL for women and 5.05 SEC/µL for men. The cutoffs for bacteria/µL (193.65 for females and 23.55 for males) indicated that the presence of bacteria in male samples may be more associated with urinary tract infections (UTIs), while in female samples, it may be associated with either UTIs or contamination/colonization scenarios. This makes the analyzer a helpful tool as QI of sample contamination in urine cultures.