bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of Platelet-Rich Fibrin for Jaw Osteonecrosis: A Case Report
Authors: Kanazirska Petya G. , Hristamyan-Cilev Mery A. , Kanarinski Nikolay D. 
Published: April 2021

Summary
We present tooth extraction in a patient treated with bisphosphonates (BPs) for cancer and at risk of osteonecrosis of the jaw. The administration of platelet-rich fibrin (PRF) is an innovative method of promoting wound healing that allows hermetic closure at the surgical site after extraction without mucoperiosteal flaps or periosteal release sections. Here, we describe the case of a 60-year-old man who had osteonecrosis of the upper jaw and underwent surgery for prostate cancer in 2012. In 2014, bone metastases were detected, and the patient was treated with Xgeva and Zometa: a two-year therapy with Xgeva, followed by treatment with Zometa. In 2018, after extraction of a tooth in the upper right jaw, a healing wound of extraction and stripping of the maxillary bone occurred. The patient was admitted for hospital treatment and underwent surgery to remove the osteonecrotic lesion, sequester and administer PRF (platelet-rich fibrin), and sew tightly. As a result of the treatment, complete re-epithelialization of the wound without infection occurred. Generally, in more invasive surgical procedures, the use of PRF to close the wells after extraction in patients receiving BP appears to be a promising alternative. Additional clinical trials will be essential t to clarify the effectiveness of PRF in preventing BP-related osteonecrosis after tooth extraction.
Sectra 3 D Human Body Visualization Table Use in Brain Abscess Diagnostics in a Child: A Case Report
Authors: Mirchev Stefan I. , Valkov Alexandar V. , Milkov Mario P. , Nikolov Georgi N. , Duhlenski Boris I. , Yildiz Malik 
Published: April 2021

Summary
Brain abscess in children is a rare and particularly severe complication of acute otitis media/Chronic suppurative otitis media (CSOM). Presenting a child with brain abscess, which was developed as a pre-surgical complication of CSOM with cholesteatoma. Visualization of the abscess on a 3-D Sectra Visualization table was performed.
An 8-year-old child who often suffered from untreated runny ear was admitted in a critical state. The history and clinical and laboratory data suggested severe chronic inflammation of the right middle ear. The examination did not reveal signs of meningeal irritation, increased intracranial pressure, excitation, sensory disorders, or focal symptoms.
Surgical treatment was performed as a radical mastoidectomy with the removal of a cholesteatoma. After a three-day uneventful postoperative period, the patient worsened. A CT scan visualized a brain abscess in the right temporal lobe. A craniotomy was performed by opening the brain abscess, with an aspiration of pus, and lavage of the cavity. After surgical and conservative treatment, the child was discharged clinically healthy on the fourteenth day. Processing the image check-ups on a Sectra 3-D visualization table helped determine the size and localization of the abscess and the choice of surgical access.
Post-Traumatic Stress Disorder and Burnout in Healthcare Professionals During the SARS-CoV-2 Pandemic: A Cross-Sectional Study
Authors: Ilias Ioannis , Mantziou Vassiliki , Vamvakas Efstratios , Kampisiouli Efstathia , Theodorakopoulou Maria , Vrettou Chariklia , Douka Evangelia , Vassiliou Alice G. , Orfanos Stylianos , Kotanidou Anastasia , Dimopoulou Ioanna 
Published: April 2021

Abstract

Introduction
Healthcare professionals who are directly involved in the diagnosis, treatment, and general care of patients with SARS-CoV-2 are at risk of developing adverse psychological reactions. A cross-sectional study of healthcare professionals aimed to determine the impact of the SARS-CoV-2 pandemic on the mental health of healthcare professionals in two of the largest referral hospitals in Athens, Greece.

Methods
The study was conducted in the two largest SARS-CoV-2 referral hospitals in Athens, Greece. An assessment and the interrelationship of post-traumatic stress disorder, using the Impact of Event Scale-Revised [IES-R]) and burnout, using the Maslach Burnout Inventory [MBI]) was carried out.

Results
A total of 162 subjects were enrolled in the study. Fifty-six (35%) had an IES-R score > 33, suggesting post-traumatic stress disorder. Forty-nine (30%) had an MBI score > 27. Seventy-five (46%) had a personal accomplishment score of < 33 and 46 (28%) had a depersonalization score >10. Stepwise backward logistic regression revealed that the only independent variable that was retained regarding the presence of post-traumatic stress disorder was the emotional exhaustion score of the MBI (at a cut-off of 24 in this scale, the 95% CI of the odds ratio for the presence of post-traumatic stress disorder was 1.077-1.173).

Conclusions
In this sample of first-line Greek healthcare professionals against SARS-CoV-2, most of them were proven to be quite resilient to this challenge. One-third of them had post-traumatic stress disorder, which depended on their degree of emotional exhaustion. Healthcare professionals, as represented by this study, performed their duties without feeling helpless and developing adverse psychological reactions.
Personalisation of Therapies in COVID-19 Associated Acute Respiratory Distress Syndrome, Using Electrical Impedance Tomography
Authors: Shono Atsuko , Kotani Toru , Frerichs Inéz 
Published: April 2021

Abstract

Introduction
Each patient suffering from severe coronavirus COVID-19-associated acute respiratory distress syndrome (ARDS), requiring mechanical ventilation, shows different lung mechanics and disease evolution. Therefore, lung protective strategies should be personalised for the individual patient.

Case presentation
A 64-year-old male patient was intubated ten days after the symptoms of COVID-19 infection presented. He was placed in the prone position for sixteen hours, resulting in a marked improvement in oxygenation. However, after being returned to the supine position, his SpO2 rapidly dropped from 98% to 91%, and electrical impedance tomography showed less ventilation at the dorsal region and a ventral shift of ventilation distribution. An incremental and decremental PEEP trial under electrical impedance tomography monitoring was carried out, confirming that the dependent lung regions were recruited with increased pressures and homogenous ventilation distribution could be provided with 14 cmH2O of PEEP. The optimal settings were reassessed next day after returning from the second session of the prone position. After four prone position-sessions in five days, oxygenation was stabilised and eventually the patient was discharged.

Conclusions
Patients with COVID-19 associated ARDS require individualised ventilation support depending on the stage of their disease. Daily PEEP trial monitored by electrical impedance tomography can provide important information to tailor the respiratory therapies.
Spontaneous Coronary Artery Dissection and Anomalous Coronary Origin – Underlying Cause of Acute Coronary Syndrome in a Young Woman: A Case Report
Authors: Lazar Roxana-Daiana , Rus Abigaela , Tolescu Cosmin , Gerculy Renata , Opincariu Diana , Benedek Imre 
Published: April 2021

Abstract

Introduction: Spontaneous coronary artery dissection (SCAD) represents a very rare and poorly understood condition that is gaining recognition as an important cause of myocardial infarction, especially among young women. The pathogenesis of SCAD is not well established yet, but several theories have been proposed.

Case presentation: We report the case of a 25-year-old woman without any history of cardiovascular disease who presented with acute anterior ST-elevation myocardial infarction (STEMI) due to the luminal obstruction generated by an intramural hematoma from a SCAD of the left main coronary artery, which was successfully treated by coronary artery stenting. Additionally, the patient presented anomalies of coronary origins (ACO) with separate emergences of the left anterior descending (LAD) artery from the left coronary cusp and the left circumflex artery (LCX) from the right coronary cusp, with no apparent clinical significance.

Conclusion: SCAD should always be included in the differential diagnosis of young patients presenting with STEMI. In case of prompt diagnosis, SCAD-STEMI patients are successfully treated with percutaneous coronary intervention (PCI). Moreover, it is of vital importance to identify variants of ACO, even without clinical relevance at the moment of the acute event, in order to initiate an appropriate management, since ACO increases the risk of routine PCI.
The Role of Matrix Metalloproteinases in the Progression and Vulnerabilization of Coronary Atherosclerotic Plaques
Authors: Opincariu Diana , Rat Nora , Benedek Imre 
Published: April 2021

Abstract
Extracellular matrix (ECM) plays an important role in the development and progression of atherosclerotic lesions. Changes in the ECM are involved in the pathophysiology of many cardiovascular diseases, including atherosclerosis. Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteases, also known as matrixins, with proteolytic activity in the ECM, being responsible for the process of tissue remodeling in various systemic pathologies, including cardiac and vascular diseases. MMPs play an important role in maintaining normal vascular structure, but also in secondary cardiovascular remodeling, in the formation of atherosclerotic plaques and in their vulnerabilization process. In addition to the assigned effect of MMPs in vulnerable plaques, they have a well-defined role in post-infarction ventricular remodeling and in various types of cardiomyopathies, followed by onset of congestive heart failure, with repeated hospitalizations and death. The aim of this manuscript was to provide a summary on the role of serum matrix metalloproteinases in the process of initiation, progression and complication of atherosclerotic lesions, from a molecular level to clinical applicability and risk prediction in patients with vulnerable coronary plaques.
Government Data Openness and Coverage. How do They Affect Trust in European Countries?
Authors: Gonzálvez-Gallego Nicolás , Nieto-Torrejón Laura 
Published: April 2021

Abstract

Purpose
This paper aims to assess if the extent of openness and the coverage of data sets released by European governments have a significant impact on citizen trust in public institutions.

Design/methodology/approach
Data for openness and coverage have been collected from the Open Data Inventory 2018 (ODIN), by Open Data Watch; institutional trust is built up as a formative construct based on the European Social Survey (ESS), Round 9. The relations between the open government data features and trust have been tested on the basis of structural equation modelling (SEM).

Findings
The paper reveals that as European governments improve data openness, disaggregation, and time coverage, people tend to trust them more. However, the size of the effect is still small and, comparatively, data coverage effect on citizens’ confidence is more than twice than the impact of openness.

Research limitations
This paper analyzes the causal effect of Open Government Data (OGD) features captured in a certain moment of time. In upcoming years, as OGD is implemented and a more consistent effect on people is expected, time series analysis will provide with a deeper insight.

Practical implications
Public officers should continue working in the development of a technological framework that contributes to make OGD truly open. They should improve the added value of the increasing amount of open data currently available in order to boost internal and external innovations valuable both for public agencies and citizens.

Originality/value
In a field of knowledge with little quantitative empirical evidence, this paper provides updated support for the positive effect of OGD strategies and it also points out areas of improvement in terms of the value that citizens can get from OGD coverage and openness.
Why Open Government Data? The Case of a Swedish Municipality
Authors: Golub Koraljka , Lund Arwid 
Published: April 2021

Abstract

Purpose
The purpose of this exploratory study is to provide modern local governments with potential use cases for their open data, in order to help inform related future policies and decision-making. The concrete context was that of the Växjö municipality located in southeastern Sweden.

Design/methodology/approach
The methodology was two-fold: 1) a survey of potential end users (n=151) from a local university; and, 2) analysis of survey results using a theoretical model regarding local strategies for implementing open government data.

Findings
Most datasets predicted to be useful were on: sustainability and environment; preschool and school; municipality and politics. The use context given is primarily research and development, informing policies and decision making; but also education, informing personal choices, informing citizens and creating services based on open data. Not the least, the need for educating target user groups on data literacy emerged. A tentative pattern comprising a technical perspective on open data and a social perspective on open government was identified.

Research limitations
In line with available funding, the nature of the study was exploratory and implemented as an anonymous web-based survey of employees and students at the local university. Further research involving (qualitative) surveys with all stakeholders would allow for creating a more complete picture of the matter.

Practical implications
The study determines potential use cases and use contexts for open government data, in order to help inform related future policies and decision-making.

Originality/value
Modern local governments, and especially in Sweden, are faced with a challenge of how to make their data open, how to learn about which types of data will be most relevant for their end users and what will be different societal purposes. The paper contributes to knowledge that modern local governments can resort to when it comes to attitudes of local citizens to open government data in the context of an open government data perspective.
Effect of Storage Temperature and Postharvest Tuber Treatment with Chemical and Biorational Inhibitors on Suppression of Sprouts During Potato Storage
Authors: Murigi Winnie Wanjiku , Nyankanga Richard Ombui , Shibairo Solomon Igosangwa 
Published: April 2021

Abstract
Consumption of ware potatoes in the tropics may be enhanced by storage under conditions that inhibit sprouting, most important of which is the temperature. The effects of storage temperatures (10 °C and 23 °C) and two alternatives to the chlorpropham (CIPC): 1,4-dimethylnaphthalene (DMN) and peppermint oil (PMO), a biorational inhibitor, were evaluated for tuber sprout suppression at postharvest. Tubers of three cultivars – ‘Asante’, ‘Kenya Mpya’, and ‘Shangi’ – with different dormancy lengths were assessed. Storage temperatures and suppressant effects on tuber sprouting, sprout length and sprout numbers per tuber were investigated in replicated storage experiments. Significant differences in sprout inhibition were observed between the two temperatures with suppressive effects higher at 10 °C than in 23 °C. CIPC had the greatest suppressive effect on tuber sprout inhibition at both temperatures. After 24 weeks of storage, the suppressive effects of CIPC at 10 °C was 100% on the three cultivars, whereas all the nontreated tubers sprouted after six (‘Shangi’), twelve (‘Asante’), fourteen (‘Kenya Mpya’) weeks of storage. At 23 °C, the effectiveness of CIPC followed the dormancy period of the cultivars, with ‘Shangi’ recording significantly more sprouted tubers followed by ‘Asante’ and ‘Kenya Mpya’. The inhibition of sprouting by DMN and PMO varied with storage temperatures and cultivars, but were significantly greater than the nontreated tubers. At 10 °C, the effectiveness of DMN treatment was equal to that of CIPC for ‘Kenya Mpya’ resulting in 100% inhibition. In the PMO treatments, complete inhibition of sprouting was observed for 18 weeks on cultivars ‘Asante’, ‘Kenya Mpya’ and 14 weeks on ‘Shangi’. At 23 °C, PMO suppressed sprouts for 14 weeks on ‘Asante’ and ‘Kenya Mpya’ and on ‘Shangi’ for 8 weeks. Storage temperature effects on sprout length and numbers varied with inhibitor type and cultivar. These findings showed that in potato tuber storage, inhibitors can replace low temperature but to an extent depending on the cultivar dormancy character and storage length, thus enabling greater consumption of potatoes in tropical regions.
Aus der Not geboren oder sinnvolle Substitution? Chancen und Grenzen des Einsatzes von „Pflegerobotern“ in der stationären Altenpflege aus ethischer Sicht
Authors: Giesbers Markus 
Published: April 2021

Abstract
This article deals with a differentiated examination of robotics and its evaluation in inpatient geriatric care. It examines the extent to which nursing robots fit into person-centered nursing work and possibly change it significantly. The advantages and new possibilities are shown, but also the dangers and problems from the point of view of different area ethics are pointed out. In the centre of the considerations are residents and employees as a benchmark for the ethical evaluation of robots in geriatric care.
Emergence and advancement of basic human capacities
Authors: Ilyin Mikhail 
Published: April 2021

Abstract
The article departs from the Teilhardean opposition of the inside (le dedans) and the outside (le dehors), notions of reflection and self-enclosure (enroulement sur lui-même), and an experimental law of recurrence (une loi expérimentale de recurrence). The author supplements them with his own apparatus of simplex-complex transformations as an epistemic principle and a set of related practices. The article starts with quantum emergence, forging its inside and outside by an interface and an alternative way to represent it as Diracean membrane, branes of the string theory, and the eigenform. The interface instrumentality for operating the inside and outside of the quantum allows their structured totality to enact agency potential. Simplex-complex transformations allow to represent an evolutionary series of agency transformations as modules of a single model up to a developed human self. The article discusses the recurrence, enclosure, and other trickeries of emergence as well as their representation with the help of cognitive metaphors likme Ouroboros or mathematical formalisms like the Moebius strip. It proceeds to chemical catalysis and autocatalysis, further to emergence of autopoiesis, and finally to biogenesis. Forms of life internalize environmental productive factor (Umwelt) by duplication, recursion, enclosing, folding, etc. to evolve a series of codes, making up integral genetic agency and genome as its key vehicle. The article considers organismic symbiosis and respective autocatalytic recursions, addresses the emergence of signal systems and cognition, which is parallel to and duplicating neural processes. It discusses primary cognitive abilities and their further autocatalytic transformations into a range of more advanced capabilities, along with the emergence of higher levelhigher-level signal systems. Finally, it ends up by discussing anthropogenesis and stepwise emergence and advancement of human language and thought in a series of internalizations of communicative contexts (frames, typical communicative settings, mementoes and typical remembrances, etc.) into codes of the first, second, and further orders.
Knowledge, complexity, power: social semiotics as metadiscipline
Authors: Hodge Bob 
Published: April 2021

Abstract
This article contributes to this special journal issue by developing concepts and methods from social semiotics to analyse, interpret and comment on text and ideas from the issue plus an RFS-project on interdisciplinarity, knowledge transfer and methodology convergence within and across STEM and HASS disciplines. It follows and extends this project’s focus on three disciplines, politics, biology and linguistics, and connects them with emerging features of contemporary knowledge production, especially complex, problematic relations between scientific and non-scientific knowledges, and new forms of operations of power on knowledge.
The article develops a modified Kuhnian framework to argue that this project can be understood as a significant intervention into a currently unfolding crisis and opportunity in knowledge. It diagnoses crises of knowledge that stem from inadequacies in traditional disciplinary organisations when confronted by challenges and “wicked problems” arising from the scale and complexity of a hyper-connected world. It sees new opportunities arising from new forms of disciplinary organization, constituted by metadisciplinary structures and functions, within a Kuhnian framework of paradigms and metaparadigms. It uses social semiotics as tool and case study, to show how disciplines can evolve into metadisciplines, and demonstrate the productivity of metadisciplines within meta- paradigm processes.
A systematic review of research on reading in English on screen and on paper
Authors: Çetin Kenan , Kılıçkaya Ferit 
Published: April 2021

Abstract
The introduction and wide use of devices, especially mobile ones, has changed the way learners read and do research for a variety of reasons, and this trend has attracted a number of studies conducted regarding reading on screen and on paper in addition to those dealing with the students’ behavior in using online resources to print ones. This paper aims at identifying the major findings and trends in reading research by describing the current state of knowledge and practice in the studies comparing reading on screen and on paper and to provide guidance for practitioners by analyzing and summarizing the existing research. The current review adopted a systematic review as the research methodology as well as the article selection and screening process. The articles published between 2009 and 2017 were reviewed, and 37 articles were included in the analysis. The review revealed that the research on onscreen and paper-based reading focused on comparing the learners’ performances in reading activities in both contexts and sharing preliminary findings and students’ views. However, the findings are inconclusive as mixed findings were produced as to the effects of reading on screen and on paper. Moreover, the review also indicates that practitioners are also interested in examining the factors and affordances in reading on screen. As a result, there is still further research needed to establish the factors affecting reading and comprehension while reading on screen and on paper.
Experiential Marketing: Effects on Brand, Customer and Market Experience, and Industrial Applications with Perspectives from Nigeria
Authors: Fatoki Oluwaseyi Philip , Fatoki Toluwase Hezekiah 
Published: April 2021

Abstract
The purpose of this study is to provide comprehensive review of experiential marketing with focus on its effects and industrial applications. We report that experiential marketing has effect on brand, consumers and the market. Experiential marketing provides a lively brand experience that give consumers the chance to engage with the brand. It promotes brand experience effects more in the Generation Y than in Generation X. Experiential marketing focuses on customer experiences. The future would be about customer relationship management (CRM), due to the fact that CRM strategy helps the company to know more about the customers. Markets are changing faster than marketing. Experiential marketing has beneficial impact on the marketing mix. Experiential marketing finds application in different businesses or industries such as hospitality and tourism, retail, health care, airline, automotive, real estate, banking, FMCG and others, in emerging markets, because it motivates customers to make faster and more positive purchasing decisions. In Nigeria, experiential marketing has become so vital to brands to cut through the media clutter.