bluuebunny/crossref_metadata_2025_split huggingface dataset:
Artificial Intelligence–Based Chatbot for Anxiety and Depression in University Students: Pilot Randomized Controlled Trial
Authors: Klos Maria Carolina , Escoredo Milagros , Joerin Angela , Lemos Viviana Noemí , Rauws Michiel , Bunge Eduardo L 
Published: May 2021

Background
Artificial intelligence–based chatbots are emerging as instruments of psychological intervention; however, no relevant studies have been reported in Latin America.

Objective
The objective of the present study was to evaluate the viability, acceptability, and potential impact of using Tess, a chatbot, for examining symptoms of depression and anxiety in university students.

Methods
This was a pilot randomized controlled trial. The experimental condition used Tess for 8 weeks, and the control condition was assigned to a psychoeducation book on depression. Comparisons were conducted using Mann-Whitney U and Wilcoxon tests for depressive symptoms, and independent and paired sample t tests to analyze anxiety symptoms.

Results
The initial sample consisted of 181 Argentinian college students (158, 87.2% female) aged 18 to 33. Data at week 8 were provided by 39 out of the 99 (39%) participants in the experimental condition and 34 out of the 82 (41%) in the control group. On an average, 472 (SD 249.52) messages were exchanged, with 116 (SD 73.87) of the messages sent from the users in response to Tess. A higher number of messages exchanged with Tess was associated with positive feedback (F2,36=4.37; P=.02). No significant differences between the experimental and control groups were found from the baseline to week 8 for depressive and anxiety symptoms. However, significant intragroup differences demonstrated that the experimental group showed a significant decrease in anxiety symptoms; no such differences were observed for the control group. Further, no significant intragroup differences were found for depressive symptoms.

Conclusions
The students spent a considerable amount of time exchanging messages with Tess and positive feedback was associated with a higher number of messages exchanged. The initial results show promising evidence for the usability and acceptability of Tess in the Argentinian population. Research on chatbots is still in its initial stages and further research is needed.
Overview of Graves Ophthalmopathy Literature From 1999 to 2019: Bibliometric Analysis
Authors: Cao Jiamin , Wang Nuo , Hou Shiying , Qi Xin , Chen Yu , Xiong Wei 
Published: May 2021

Background
Research on Graves ophthalmopathy has increased remarkably over the last 2 decades; however, few statistical analyses of the data presented in these publications have been conducted.

Objective
This study aims to detect and analyze emerging trends and collaboration networks in Graves ophthalmopathy research.

Methods
Graves ophthalmopathy–related publications from 1999 to 2019 were collected from the Web of Science Core Collection Database. Collected publications were restricted by category (article or review) and language (English). Bibliometric analyses included changes in the annual numbers of publications, journals, authors, countries, institutions, keywords, and references.

Results
In total, 3051 publications that met the criteria were collected. The number of annual publications has exhibited an increasing trend over the last 20 years. The journal Thyroid ranked first, publishing 183 Graves ophthalmopathy–related studies. There was no evidence of a relationship between impact factor (IF) and the number of publications (P=.69). The author Smith TJ had the largest number of publications on Graves ophthalmopathy (n=83). Of the countries that had published Graves ophthalmopathy–related articles, the United States had the largest number (n=784) and the highest centrality (0.18). Among institutions, the University of Pisa (Italy) contributed the most Graves ophthalmopathy–related articles (n=114). The most recent burst keywords (proliferation, rituximab, and selenium) and references may provide clues on emerging trends in research and clinical practice.

Conclusions
This bibliometric analysis highlights countries, institutions, and authors who contributed to Graves ophthalmopathy–related publications. Emerging trends in Graves ophthalmopathy research, based on burst keywords and references, may provide clues relevant to clinical practice and future research.
Emerging Trends and Thematic Evolution of Breast Cancer: Knowledge Mapping and Co-Word Analysis
Authors: Sadatmoosavi Ali , Tajedini Oranus , Esmaeili Omid , Abolhasani Zadeh Firouzeh , Khazaneha Mahdiyeh 
Published: May 2021

Background
One of the requirements for scientists and researchers to enter any field of science is to have a comprehensive and accurate understanding of that discipline.

Objective
This study aims to draw a science map, provide structural analysis, explore the evolution, and determine new trends in research articles published in the field of breast cancer.

Methods
This study comprised a descriptive survey with a scientometric approach. Data were collected from MEDLINE using a search strategy based on Medical Subject Heading (MeSH) terms. This study used science mapping, which provides a visual representation and a longitudinal evolution of possible interrelations between scientific areas, documents, or authors, thus reflecting the cognitive architecture of science mapping. For this scientometric evaluation of the topic of breast cancer research, a very long period was considered for data collection. Moreover, due to the availability of numerous publications in the database, the assessment was divided into three different periods ranging from 1988 to 2020.

Results
A total of 12,577 records related to scientometric studies were extracted. The field of breast cancer research demonstrated three diagrams containing the most relevant themes for the three chronological periods evaluated. Each diagram was plotted based on the centrality and density linked to each research topic. The research output in the field was observed to revolve around 8 areas or themes: radiation injury, cardiovascular disease, fibroadenoma, antineoplastic agent, estrogen antagonistic, immunohistochemistry, soybean, and epitopes, each represented with different colors.

Conclusions
In the strategic diagrams, the themes were both well developed and important for the structuring of a research field. The first quadrant comprised motor themes of the specialty, which present strong centrality and high density (eg, corticosteroid antineoplastic age, stem cell, T-lymphocyte, protein tyrosine kinase, dietary, and phosphatidyl inositol-3-kinase). In the second quadrant of diagram, themes have well-developed internal ties but unimportant external ties, as they are of only marginal importance for the field. These themes are very specialized and peripheral (eg, DNA-binding). In the third quadrant, themes are both weakly developed and marginal. The themes in this quadrant have low density and centrality and mainly represent either emerging or declining themes (eg, ovarian neoplasm). Themes in the fourth quadrant of the strategic diagram are considered important for a research field but are not fully developed. This quadrant contains transversal and general, basic themes (eg, immunohistochemistry). Scientometric analysis of breast cancer research can be regarded as a roadmap for future research and policymaking for this important field.
The Psychosocial Impacts of COVID-19 on a Sample of Australian Adults: Cross-sectional Survey and Sentiment Analysis
Authors: Ryan Jillian , Sellak Hamza , Brindal Emily 
Published: May 2021

BackgroundThe COVID-19 pandemic has had enormous impacts on people’s lives, including disruptions to their normal ways of behaving, working, and interacting with others. Understanding and documenting these experiences is important to inform the ongoing response to COVID-19 and disaster preparedness efforts.ObjectiveThe aim of this study was to examine the psychosocial impacts of COVID-19 on a sample of Australian adults.MethodsThe data analyzed were derived from a larger cross-sectional survey of Australian adults that was administered during the month of May 2020. Participants (N=3483) were asked in which ways COVID-19 had most greatly impacted them; the responses produced a text data set containing 1 COVID-19 impact story for each participant, totaling 86,642 words. Participants also completed assessments of their sociodemographic characteristics (sex, age, financial stress), level of concern related to COVID-19, personality trait profile, and satisfaction with life. Impact stories were analyzed using sentiment analysis and compared against the Theoretical Domains Framework to determine the most frequently impacted life domains. Finally, a multinomial regression analysis, stratified by participant sex, was conducted to identify the associations of psychological and demographic socializations with sentiment toward COVID-19.ResultsIn total, 3483 participants completed the survey, the majority of whom were female (n=2793, 80.2%). Participants’ impact stories were most commonly categorized as neutral (1544/3483, 44.3%), followed by negative (1136/3483, 32.6%) and positive (802/3483, 23.1%). The most frequently impacted life domains included behavioral regulation, environmental context and resources, social influences, and emotions, suggesting that the COVID-19 pandemic was impacting these areas of participants’ lives the most. Finally, the regression results suggested that for women, lower satisfaction with life and higher financial stress were associated with increased likelihood of negative, rather than positive, sentiment (P<.001); however, the proportion of variance in the sentiment that was explained was very small (<5%).ConclusionsParticipant sentiment toward COVID-19 varied. High rates of neutral and negative sentiment were identified. Positive sentiment was identified but was not as common. Impacts to different areas of people’s lives were identified, with a major emphasis on behavioral regulation and related domains such as social influences, environmental context and resources, and emotions. Findings may inform the development of mental health and social support resources and interventions to help alleviate the psychosocial consequences of disaster response measures.
Hidrología de ecosistemas limitados: estuarios de cuña salina
Authors: Tapanes Juan José 
Published: June 2021

Se presenta un estudio realizado en el estuario del río Zaza, durante el año 1973, en el cual se determinaron las condiciones hidrológicas generales del mismo, tales como temperatura, salinidad, oxígeno disuelto, densidad y estabilidad de las aguas, así como procesos de circulación, mezcla y estancamiento. Estas investigaciones nos han permitido clasificar este estuario, y además, inferir que las condiciones encontradas pueden ser extrapoladas a otros estuarios similares que presenten la construcción de represas, aguas arriba de sus desembocaduras.
Procesos de acreditación de la calidad en la Carrera de Enseñanza del inglés para I y II ciclos en la UNED: fortalezas y compromisos de mejoramiento
Authors: Guillén-Saborío María Laura , Brizuela-Gutiérrez Tobías 
Published: May 2021

La calidad en la educación superior es un asunto que debe reunir a todos los actores posibles, comprometidos con el objetivo de proveer las herramientas más eficaces y actualizadas en el plano educativo de modo que se puedan capacitar y formar profesionales versátiles que aporten a la construcción de una sociedad más justa, democrática e inclusiva.
La educación universitaria debe siempre procurar y sistematizar procesos de autoevaluación y en el caso de las carreras, obtener la certificación de acreditación.
Este artículo tiene como fin describir por un lado los procesos a los que la UNED se ha sometido con el fin de que sus carreras universitarias puedan lograr la acreditación de SINAES y por otra parte sistematizar las acciones de la Carrera de la Enseñanza del Inglés en estos procesos, sus fortalezas y oportunidades de mejora plasmadas en el documento denominado compromisos de mejoramiento
Desarrollo de las habilidades de pensamiento crítico, creatividad e innovación y resolución de problemas en Ciencias Noveno año, Costa Rica
Authors: Pereira-Chaves José , Jiménez-Salazar María Andreina , Cubero-Jiménez Anyela , Quesada-Vargas Roberto , Jiménez-Sánchez Susana 
Published: May 2021

La presente investigación se realiza en el segundo semestre del 2018 y tuvo como propósito identificar el desarrollo de las habilidades de pensamiento crítico, creatividad e innovación y resolución de problemas en Ciencias Noveno año, Costa Rica, las cuales deben ser abordadas entre otras 10 habilidades más según la propuesta o transformación curricular del Ministerio de Educación Pública (MEP). El paradigma empleado es naturalista, con un enfoque cualitativo dominante y un diseño fenomenológico, donde se aplican tres estudios de casos relacionados con temas sobre a la vida cotidiana, con el fin de determinar el desarrollo de la habilidad en el proceso de enseñanza y el aprendizaje. Los sujetos de investigación son 73 estudiantes de tres colegios nocturnos de la regional de educación de Heredia. El análisis de la información se hace mediante una rúbrica preestablecida donde se determina el grado de desarrollo de la habilidad; entre los principales hallazgos se obtiene que las tres habilidades estudiadas tienen un desarrollo bajo en las clases de ciencias, lo que da indicios a que la potenciación de las mismas en el aula no son abordadas, a pesar de que el programa de estudio de Ciencias III ciclo lo exige, por lo que es fundamental que se aborde integralmente con los docentes mediante capacitación y se logre comprender e interiorizar la importancia de una mediación pedagógica en el aula, que potencie las habilidades mediante la metodología de la indagación para Ciencias.
Experiencias internacionales en la evaluación de programas de Informática centrada en el curriculum y en el proceso de enseñanza-aprendizaje. Estudio de caso: Argentina, España y México.
Authors: Bonilla-Calero Ana Isabel , Serrano-García María Ángeles 
Published: May 2021

Este trabajo tiene como objetivo analizar cómo se desarrollan las acreditaciones internacionales en el ámbito profesional de informática basados en resultados de aprendizaje seleccionados por académicos/as y profesionales de diferentes países en el ámbito de la informática. Los datos utilizados en este estudio se han obtenido de las evaluaciones realizadas por Agencia Nacional de Evaluación de la Calidad y Acreditación (ANECA) en España, Argentina y México entre enero del 2014 y julio del 2020 y de las que están en curso en el momento del cierre del artículo. También, se ha analizado la información obtenida en la meta evaluación realizada anualmente al Programa SIC. 26 universidades han obtenido el sello de Euro-Inf para sus títulos/programas educativos de informática en el periodo analizado. Desde el 2020 la evaluación se realiza virtualmente en su totalidad, debido a la pandemia provocada por la COVID-19.
Model Inside Outside Circle dan Aktivitas Belajar Terhadap Prestasi Belajar Ekonomi
Authors: Ikasari Diah Marheni , Rufi’I Rufi’I , Walujo Djoko Adi 
Published: June 2021

Hasil belajar penilaian menunjukkan bahwa nilai rata-rata yang dicapai masih berada di bawah nilai KKM Ekonomi yang telah ditetapkan guru. Hal ini disebabkan karena aktivitas belajar siswa belum mampu membuat siswa termotivasi untuk belajar. Penelitian ini bertujuan untuk menganalisis perbedaan prestasi belajar siswa pada pelajaran ekonomi antara kelompok siswa yang diajarkan dengan menggunakan model Inside Outside Circle (IOC) dan model ceramah bervariasi kelompok siswa yang mempunyai aktivitas belajar tinggi dan yang mempunyai aktivitas belajar rendah, serta interaksi antara penggunaan model IOC dan aktivitas belajar siswa terhadap prestasi belajar. Jenis penelitian ini yakni penelitian kuasi eksperimen dengan pendekatan secara kuantitatif. Pengumpulan data dalam penelitian ini menggunakan tes prestasi belajar dan angket. Uji analisis data menggunakan ANOVA untuk mengolah dan menganalisis data. Hasil penelitian ini yaitu, hipotesis pertama diperoleh pengaruh positif nilai F sebesar 21,840 dengan signifikansi sebesar 0,000 (Sig < 0,05), hipotesis kedua menunjukkan angka signifikansi yaitu Sig. 0,001 < 0,05, hipotesis ketiga menunjukkan angka signifikansi yaitu Sig 0,036 < 0,05. Simpulan dalam penelitian ini yaitu penerapan model pembelajaran Inside Outside Circle dan aktivitas belajar siswa berpengaruh kuat secara signifikansi terhadap peningkatan prestasi belajar siswa pada pelajaran Ekonomi. Implikasi dari penelitian ini yakni untuk dapat meningkatkan prestasi belajar siswa serta memberikan efek pembelajaran bermakna terhadap aktivitas belajar siswa.
Oferta assistencial de leitos de referência à covid-19 nas regiões de saúde de Pernambuco
Authors: Pontes Juliana Leão , Cardoso Ana Cláudia De Andrade , Santos Daiane Cordeiro , Oliveira Pollyana Ribas , Lemos Anna Renata Pinto , Neto Aristides Vitorino De Oliveira , Neto Giliate Cardoso Coelho 
Published: May 2021

Trata-se de um estudo descritivo que utilizou documentos e dados oficiais com objetivo de analisar a distribuição da oferta de leitos SUS para tratamento da infecção pelo covid-19 em Pernambuco, por região de saúde. Observa-se interiorização da doença com registro em todas as regiões de saúde, o que ocasionou diminuição da proporção de casos em residentes da Região Metropolitana do Recife, passando de 90,0% para 47,1%. Destaca-se ocorrência de SRAG em 22% dos casos. Quanto à oferta dos leitos, identificou-se crescimento de 1,29 para 4,74 leitos/10.000 habitantes, havendo distribuição homogênea entre as macrorregiões de saúde, condição relevante no enfrentamento à pandemia. Os registros de Autorização de Internação Hospitalar revelaram uma média de 7,05 dias de permanência no leito, aumentando para 9,97 dias nos internamentos em UTI. Por fim, destaca-se o importante legado deixado pela covid-19: o urgente e indispensável fortalecimento da saúde pública brasileira.Palavras-chave: Infecções por Coronavírus, Assistência à Saúde, Regionalização, Planos de Contingência The offer of reference hospital beds to treatment of covid-19 in the health regions of Pernambuco ABSTRACTThis is a descriptive study that used official documents and data in order to analyze the distribution of the supply of SUS hospital beds for the treatment of covid-19 infection in Pernambuco by health region. It been observed an internalization of the disease registrated in all health regions, which caused a decrease from 90.0% to 47.1% in the proportion of cases in residents of the metropolitan region of Recife. The occurrence of SARS stands out in 22% of cases. As for the supply of hospital beds, there was a growth from 1.29 to 4.74 beds per 10,000 inhabitants, with a homogeneous distribution among the health macro-regions, a relevant condition in facing the pandemic. Records of hospitalization authorization revealed an average of 7.05 days in bed, increasing to 9.97 days in ICU admissions. Finally, we highlight the important legacy left by covid-19: the urgent and indispensable strengthening of Brazilian public health.Keywords: Coronavirus Infections, Delivery of Health Care, Regional Health Planning, Contingency Plans
Multi-Drug Resistance Genes associated with some Gram-Negative Bacteria Isolates from Shellfish in Iko and Douglas River Estuaries, in Nigeria
Authors: Udoekong Nsikan Samuel , Bassey Bassey Enya , Asuquo Anne E. , Akan Otobong Donald , Ifeanyi Casmir Ifeanyichukwu Cajetan 
Published: May 2021

Background: Multi drug resistant bacterial agents that contaminate seafood cause several diseases in humans and are widely documented as a global public health challenge.
Methods: This study evaluated the microbiological and antimicrobial resistance genes profiles of bacterial Isolates from shellfish vended at Iko and Douglas Creeks of Cross River State, Nigeria. A total of 540 shellfish (117 clams, 88 oysters, 136 periwinkles) samples were collected from various vendor at the two Creeks were analyzed. The samples were processed using standard microbiological methods to identify bacterial pathogens. Antimicrobial susceptibility was assayed using the Kirby-Bauer disk diffusion method. Isolates were screened for antimicrobial resistant genes using polymerase chain reaction.
Results: Overall, a total of 135 bacteria isolates were identified. The most common isolate was Alcaligenes species 53(39.2%) followed by Pseudomonas species 44(32.6%), Providencia species 25(18.5%), Vibrio species 6(4.4%), and Paenalcaligenes species 7(5.2%). The isolates showed varying susceptibilities to Imipenem (36%) and amikacin (28%) but were all resistant to Trimethoprim-Sulfamethoxazole. Fifty-three isolates had a multiple antibiotic resistance index (MARI) of ≥0.9 - 1.0. Most of the bacterial isolates were detected with TEM genes (82.2%), SHV (51.8%,), VIM (50.3%) resistance genes. None of the isolates expressed Veb gene. Only 40.7% of the isolates expressed QnrB gene while none expressed QnrA and QnrS.
Conclusion: The detection of these multidrug resistant clinically relevant bacterial species suggests a significant linkage of commonly consumed seafood in the community and environmental spread of MDR bacteria.
Hydraulic Modelling of Different Working Regimes in Water Pipeline. Case Study: Mihaliq – Water Treatment Plant “SHKABAJ”
Authors: Vataj Gjelosh , Berisha Xhevat , Sejfijaj Zenel 
Published: May 2021

In the flow through the pipes, we have unstable movements when, due to the closing or opening of the valve or other hydraulic equipment, the speed of movement of the liquid changes. The change in velocity causes inertial forces to arise in the liquid which cause pressure changes in the flow. The phenomenon characterized by these pressure changes is called hydraulic water hammer.
The hydraulic shock can be called the increase or decrease of the flow pressure in the pipe caused by the change in time (in any section) of the flow velocity.
The objective of this paper is to provide information and resources to assist water company management and their staff in identifying and implementing opportunities to reduce energy use. Case study is Pumping Station in Milloshevo managed by Regional Water Company “PRISHTINA”.
Restoration of a Traumatically Amputated Finger by a Traditional Glove-Type Prosthesis: A Case Report
Authors: Kaur Simarpreet , Kaur Mandeep , Verma Anupama , Singh Tarun 
Published: May 2021

Background: Each organ serves a specific function in the human body. Congenital absence or loss of even minor parts of it can pose extreme psychological trauma in addition to the functional impairment and esthetic issues encountered by the individual. Amputation of complete or a part of phalange of hand is frequently encountered either due to trauma or necrosis. Restoration of such defects become mandatory to improve general form and function combined with the esthetic requirements of the patient. It can either be done by microvascular reconstruction or prosthetic rehabilitation. The latter becomes the means of choice in cases where the former is either not possible, unavailable, unsuccessful, or unaffordable.
Case Report: A case report has been presented of a 60 years old patient with an old traumatic partially amputated index finger.
Treatment Plan: A custom-made glove-type prosthesis was fabricated using silicone elastomer.
Conclusion: A ring is provided for better esthetics and special adhesive is recommended for retention of the prosthesis.