bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fast‐converging robust PR‐P controller designed by using symmetrical pole placement method for current control of interleaved buck converter‐based PV emulator
Authors: Yanarates Cagfer , Zhou Zhongfu 
Published: November 2021

AbstractIn this study, the interleaved buck converter‐based photovoltaic (PV) emulator current control is presented. A proportional‐resonant‐proportional (PR‐P) controller is designed to resolve the drawbacks of conventional PI controllers in terms of phase management, which means balancing currents evenly between active phases to avoid thermally stressing and provide optimal ripple cancelation in the presence of parameter uncertainties. The resonant path of the controller (PR) with a constant proportional unity gain is designed considering the changing dynamics of a notch filter by pole placement method (adding mutually complementary poles to the notch transfer function) at PWM switching frequency. The proportional gain path (P) of the controller is used to determine the compatibility of the controller with parameter uncertainty of the phases and designed by utilizing loop‐shaping method. The proposed controller shows superior performance in terms of 10 times faster‐converging transient response, zero steady‐state error with significant reduction in current ripple. Equal load sharing that constitutes the primary concern in multiphase converters is achieved with the proposed controller. Implementing of robust control theory involving comprehensive time and frequency domain analysis reveals 13% improvement in the robust stability margin and 12‐degree bigger phase toleration with the PR‐P controller. In addition to these, the proposed unconventional design process of the controller reduces the computational complexity and provides cost‐effectiveness and simple implementation. Moreover, implementing of auxiliary resistor‐capacitor (RC) circuits parallel with the inductors to sense the current in each phase removes the need for current measurement sensors that contribute to overall cost of the system.
Development of an incentive model for renewable energy resources using forecasting accuracy in South Korea
Authors: Kong Junhyuk , Oh Seongmun , Kang Byung O , Jung Jaesung 
Published: November 2021

AbstractThis study presents an incentive model for a renewable energy source (RES) supplier, based on forecasting accuracy. The incentive model imposes responsibility of forecasting to RES suppliers by providing an additional revenue or penalty, according to forecasting accuracy. For this, a profit analysis reflecting the current environment was performed. The structure of the incentive model is designed based on the results of profit analysis. Subsequently, the price parameter was determined using an artificially generated forecasting error of the RES. In addition, the utilization of energy storage system (ESS) is analyzed, including the operation algorithm and optimal sizing, to verify the utility of the ESS when the incentive model is applied. In the case study, the actual price data and RES data from South Korea were used. The results show that the incentive model can provide a high level of profit or penalty for the RES supplier, according to the forecasting accuracy. It is also shown that the optimal capacity of the ESS based on econometrics can be reduced by more than 50% compared with the current environment, thereby reducing the burden on the ESS investment of RES suppliers.
Widespread effects of dMRI data quality on diffusion measures in children
Authors: Koirala Nabin , Kleinman Daniel , Perdue Meaghan V. , Su Xing , Villa Martina , Grigorenko Elena L. , Landi Nicole 
Published: November 2021

AbstractDiffusion magnetic resonance imaging (dMRI) datasets are susceptible to several confounding factors related to data quality, which is especially true in studies involving young children. With the recent trend of large‐scale multicenter studies, it is more critical to be aware of the varied impacts of data quality on measures of interest. Here, we investigated data quality and its effect on different diffusion measures using a multicenter dataset. dMRI data were obtained from 691 participants (5–17 years of age) from six different centers. Six data quality metrics—contrast to noise ratio, outlier slices, and motion (absolute, relative, translation, and rotational)—and four diffusion measures—fractional anisotropy, mean diffusivity, tract density, and length—were computed for each of 36 major fiber tracts for all participants. The results indicated that four out of six data quality metrics (all except absolute and translation motion) differed significantly between centers. Associations between these data quality metrics and the diffusion measures differed significantly across the tracts and centers. Moreover, these effects remained significant after applying recently proposed harmonization algorithms that purport to remove unwanted between‐site variation in diffusion data. These results demonstrate the widespread impact of dMRI data quality on diffusion measures. These tracts and measures have been routinely associated with individual differences as well as group‐wide differences between neurotypical populations and individuals with neurological or developmental disorders. Accordingly, for analyses of individual differences or group effects (particularly in multisite dataset), we encourage the inclusion of data quality metrics in dMRI analysis.
Stage at diagnosis and survival among adolescents and young adults with lymphomas following the Affordable Care Act implementation in California
Authors: Abrahão Renata , Cooley Julianne J. P. , Maguire Frances B. , Parikh‐Patel Arti , Morris Cyllene R. , Schwarz Eleonor Bimla , Wun Ted , Keegan Theresa H. M. 
Published: November 2021

AbstractAdolescents and young adults (AYAs, 15‐39 years) are the largest uninsured population in the Unites States, increasing the likelihood of late‐stage cancer diagnosis and poor survival. We evaluated the associations between the Affordable Care Act (ACA), insurance coverage, stage at diagnosis and survival among AYAs with lymphoma. We used data from the California Cancer Registry linked to Medicaid enrollment files on AYAs diagnosed with a primary non‐Hodgkin (NHL; n = 5959) or Hodgkin (n = 5378) lymphoma pre‐ACA and in the early and full ACA eras. Health insurance was categorized as continuous Medicaid, discontinuous Medicaid, Medicaid enrollment at diagnosis/uninsurance, other public and private. We used multivariable regression models for statistical analyses. The proportion of AYAs uninsured/Medicaid enrolled at diagnosis decreased from 13.4% pre‐ACA to 9.7% with full ACA implementation, while continuous Medicaid increased from 9.3% to 29.6% during this time (P < .001). After full ACA, AYAs with NHL were less likely to be diagnosed with Stage IV disease (adjusted odds ratio [aOR] = 0.84, 95% confidence interval [CI] = 0.73‐0.97). AYAs with lymphoma were more likely to receive care at National Cancer Institute‐Designated Cancer Centers (aOR = 1.42, 95% CI = 1.28‐1.57) and had lower likelihood of death (adjusted hazard ratio = 0.54, 95% CI = 0.46‐0.63) after full ACA. However, AYAs from the lowest socioeconomic neighborhoods, racial/ethnic minority groups and those with Medicaid continued to experience worse survival. In summary, AYAs with lymphomas experienced increased access to healthcare and better clinical outcomes following Medicaid expansion under the ACA. Yet, socioeconomic and racial/ethnic disparities remain, calling for additional efforts to decrease health inequities among underserved AYAs with lymphoma.
A novel method of transvesicoscopic ureteral reimplantation of an ectopic ureter with a mate ureter in a duplex kidney
Authors: Nishio Hidenori , Mizuno Kentaro , Matsumoto Daisuke , Kato Taiki , Kamisawa Hideyuki , Kurokawa Satoshi , Nakane Akihiro , Maruyama Tetsuji , Yasui Takahiro , Hayashi Yutaro 
Published: November 2021

IntroductionThe reimplantation of an ectopic ureter is still performed as an open surgery, although laparoscopic or robot‐assisted laparoscopic surgery has gained popularity as a minimally invasive treatment for pediatric urological disorders.Case presentationA 15‐day‐old Japanese boy was referred to our hospital with right hydronephrosis. A detailed examination revealed complete ureteral duplication on the right side and a dilated ectopic upper pole ureter, opening into the prostatic urethra. Since the patient had recurrent febrile urinary tract infections, we performed plication and ureteral reimplantation of the dilated ectopic ureter using a transvesicoscopic surgical method at the age of 2 years and 5 months.ConclusionWe safely performed transvesicoscopic ureteral reimplantation for an ectopic upper pole ureter with a mate ureter in a duplex kidney, following the detection of an ectopic ureter within the bladder, due to the prior understanding of the wrapping of both ureters in a common sheath.
Effects of photobiomodulation therapy on regulation of myogenic regulatory factor mRNA expression in vivo: A systematic review
Authors: Shepherd David W. , Norris Joseph M. , Simpson Benjamin S. , Player Darren J. , Whitaker Hayley C. 
Published: November 2021

AbstractNon‐invasive promotion of myogenic regulatory factors (MRFs), through photobiomodulation therapy (PBMT), may be a viable method of facilitating skeletal muscle regeneration post‐injury, given the importance of MRF in skeletal muscle regeneration. The aim of this systematic review was to collate current evidence, identifying key themes and changes in expression of MRF in in vivo models. Web of Science, PubMed, Scopus and Cochrane databases were systematically searched and identified 1459 studies, of which 10 met the inclusion criteria. Myogenic determination factor was most consistently regulated in response to PBMT treatment, and the expression of remaining MRFs was heterogenous. All studies exhibited a high risk of bias, primarily due to lack of blinding in PBMT application and MRF analysis. Our review suggests that the current evidence base for MRF expression from PBMT is highly variable. Future research should focus on developing a robust methodology for determining the effect of laser therapy on MRF expression, as well as long‐term assessment of skeletal muscle regeneration.
Association of a common genetic variant (insertion/deletion) in ACE gene with prostate cancer susceptibility in a Tunisian population
Authors: Said Rahma , Jenni Rim , Boussetta Sami , Ammous Feryel , Zouari Skander , Zaghbib Selim , Chakroun Marouene , Derouiche Amine , Chebil Mohamed , Ouerhani Slah 
Published: November 2021

AbstractBackgroundAngiotensin‐converting enzyme (ACE) plays a pivotal role in several pathologies including cancers. The association of insertion/deletion (I/D) polymorphism of the ACE gene with prostate cancer (PC) risk remains controversial. We aimed to investigate for the first time, to our Knowledge, in North Africa the potential relationship between ACE I/D polymorphism with PC susceptibility and clinical outcomes of PC patients.MethodsThis case‐control study included 143 healthy individuals and 124 patients diagnosed with PC. Using genomic DNA, the samples were genotyped for ACE I/D polymorphism by polymerase chain reaction (PCR).ResultsWe found that The D allele is significantly associated with an increased risk of PC and D/D + D/I genotypes were at 3 times increased risk of PC ([p = 0.005], OR = 2.95, IC 95% = 1.26–7.09) compared with I/I genotype (p = 0.003, OR = 0.3, IC 95% = 0.12–0.74). We observed an association between D/D and D/I genotypes with advanced age (≥70 years) (p = 0.014; r2 = 0.22). Furthermore, there is a significant prediction of advanced Gleason score ≥8 based on epidemiological parameters and ACE genotype (p = 0.000; R2 = 0.349), although no significant association was observed with stage and metastasis.ConclusionThe ACE I/D polymorphism is likely to predispose to PC and could play a role in PC progression and aggressiveness.
Composite proton exchange membrane of cellulose triacetate polymer integrated with polyacrylic acid and triazole based copolymer for balanced proton conduction and methanol permeability
Authors: Karunanithi Deepa , Balaguru Sasikumar , Swaminathan Elakkiya , Gangasalam Arthanareeswaran 
Published: November 2021

AbstractBACKGROUNDProton exchange membranes (PEMs) could prompt proton transport with long‐term oxidative and hydrolytic durability with little methanol crossover under humidified conditions. Cellulose triacetate (CTA)‐based PEMs were fabricated by reinforcing with 4 wt.% of polyacrylic acid (PAA) and polymerized triazole (PTZA) combination of acrylic acid/triazole acrylate copolymer.RESULTSThe presence of PAA and PTZA copolymer in the CTA membrane was confirmed using Fourier transform infrared spectroscopy and X‐ray diffraction. The variations of proton conductivity, methanol crossover and water uptake of the PTZA copolymer‐reinforced CTA matrix were evaluated. Higher proton conductivity of 2.313 × 10−4 S cm−1 and minimal methanol permeability of 1.773 × 10−7 cm2 s−1 were obtained for the CTA/PTZA–20 membrane compared to a pristine CTA membrane. Furthermore, the oxidative tolerability was about 99.6% for CTA/PAA membrane, and hydrolytic stability was 97.78% for the CTA/PTZA–20 membrane, higher than that of the pristine CTA membrane.CONCLUSIONSThe increase in proton conduction compared to pristine CTA membrane could be attributed to the presence of triazole moiety, which acts as a proton facilitator in the conduction process. Additionally, an increase in hydrolytic stability, oxidative tolerability and lower methanol crossover results indicated that the PTZA copolymer‐reinforced CTA PEMs have potential for use in fuel cell applications. © 2021 Society of Chemical Industry (SCI).
Lymphoid blast crisis after prolonged treatment‐free remission in chronic myeloid leukaemia after tyrosine kinase inhibitor de‐escalation during the COVID‐19 pandemic
Authors: Avenoso Daniele , Milojkovic Dragana , Clark James , Pocock Christopher , Potter Victoria , Yallop Deborah , Hannah Guy 
Published: November 2021

AbstractDuring the COVID‐19 pandemic, access to health services has been considerably restricted and furthermore, patients have been reluctant to attend for routine monitoring, and this may have had a negative impact in the management of patients affected with haematological disorders. Sudden blast crisis in chronic myeloid leukaemia is categorized as a rapid onset of blastic phase, after a documented ‘optimal’ response to tyrosine kinase inhibitor (TKI) therapy and within 3 months of a normal complete blood count. Herein, we describe a case of patient who developed sudden blast crisis after TKI while in treatment‐free remission.
Association Between Heart Failure With Preserved Left Ventricular Ejection Fraction and Impaired Left Atrial Phasic Function in Hypertrophic Cardiomyopathy: Evaluation by Cardiac MRI Feature Tracking
Authors: Shi Rui , Shi Ke , Huang Shan , Li Xiang , Xia Chun‐Chao , Li Yuan , He Sen , Li Zhen‐Lin , He Yong , Guo Ying‐Kun , Yang Zhi‐Gang 
Published: November 2021

BackgroundThe majority of heart failure (HF) in hypertrophic cardiomyopathy (HCM) manifests as a phenotype with preserved left ventricular (LV) ejection fraction; however, the exact contribution of left atrial (LA) phasic function to HF with preserved ejection fraction (HFpEF) in HCM remains unresolved.PurposeTo define the association between LA function and HFpEF in HCM patients using cardiac magnetic resonance imaging (MRI) feature tracking.Study TypeRetrospective.PopulationOne hundred and fifty‐four HCM patients (HFpEF vs. non‐HF: 55 [34 females] vs. 99 [43 females]).Field Strength/Sequence3.0 T/balanced steady‐state free precession.AssessmentLA reservoir function (reservoir strain [εs], total ejection fraction [EF]), conduit function (conduit strain [εe], passive EF), booster‐pump function (booster strain [εa] and active EF), LA volume index, and LV global longitudinal strain (LV GLS) were evaluated in HCM patients.Statistical TestsChi‐square test, Student's t‐test, Mann–Whitney U test, multivariate linear regression, logistic regression, and net reclassification analysis were used. Two‐sided P < 0.05 was considered statistically significant.ResultsNo significant difference was found in LV GLS between the non‐HF and HFpEF group (−10.67 ± 3.14% vs. −10.14 ± 4.01%, P = 0.397), whereas the HFpEF group had more severely impaired LA phasic strain (εs: 27.40 [22.60, 35.80] vs. 18.15 [11.98, 25.90]; εe: 13.80 [9.20, 18.90] vs. 7.95 [4.30, 14.35]; εa: 13.50 [9.90, 17.10] vs. 7.90 [5.40, 14.15]). LA total EF (37.91 [29.54, 47.94] vs. 47.49 [39.18, 55.01]), passive EF (14.70 [7.41, 21.49] vs. 18.07 [9.32, 24.78]), and active EF (27.19 [17.79, 36.60] vs. 36.64 [26.63, 42.71]) were all significantly decreased in HFpEF patients compared with non‐HF patients. LA reservoir (β = 0.90 [0.85, 0.96]), conduit (β = 0.93 [0.87, 0.99]), and booster (β = 0.86 [0.78, 0.95]) strain were independently associated with HFpEF in HCM patients. The model including reservoir strain (Net Reclassification Index [NRI]: 0.260) or booster strain (NRI: 0.325) improved the reclassification of HFpEF based on LV GLS and minimum left atrial volume index (LAVImin).Data ConclusionLA phasic function was severely impaired in HCM patients with HFpEF, whereas LV function was not further impaired compared with non‐HF patients.Level of Evidence4Technical EfficacyStage 3
Investigating the associations between childhood trauma and cardiovascular health in midlife
Authors: Caceres Billy A. , Britton Laura E. , Cortes Yamnia I. , Makarem Nour , Suglia Shakira F. 
Published: November 2021

AbstractGrowing evidence suggests that childhood trauma is associated with poorer cardiovascular health in adulthood, but few studies have examined potential mediators of these associations. We examined the links between different forms of childhood trauma (i.e., abuse, neglect, cumulative trauma) and cardiovascular health and explored potential mediators. Cross‐sectional data from 1,251 participants in the National Survey of Midlife Development in the United States’ II Biomarker Project were analyzed. Path analyses were conducted to examine the associations between childhood trauma and cardiovascular health (i.e., American Heart Association's Life's Simple 7 [LS7] score). Depressive symptoms and sleep quality were explored as potential mediators, and exploratory analyses examined whether these associations were moderated by sex. Women reported more severe childhood emotional and sexual abuse and emotional neglect, p < .001 to p = .018, and higher LS7 scores, p = .027, than men. Path analyses demonstrated the total effects of increasing severity of all forms of childhood trauma with LS7 scores were significant, and cumulative childhood trauma was inversely associated with LS7 score Bs = ‐0.306– ‐0.076, p < .001–p = .048. The range of total effects of different forms of childhood trauma on LS7 scores mediated by depressive symptoms and sleep quality was 26.8%–57.5%. Sex moderated the associations between all forms of childhood trauma and cardiovascular health. Longitudinal studies are needed that examine mediators of the associations between childhood trauma and cardiovascular health. Findings suggest sex‐specific, trauma‐informed approaches for cardiovascular disease prevention in adults exposed to childhood trauma may be needed.
Racial discrimination and other adverse childhood experiences as risk factors for internalizing mental health concerns among Black youth
Authors: Bernard Donte L. , Smith Quinton , Lanier Paul 
Published: November 2021

AbstractAdverse childhood experiences (ACEs) have been consistently linked to a reduction in healthy psychological adjustment among youth. Emergent evidence suggests that there are culturally specific ACEs, such as racial discrimination, that are particularly harmful to the mental health of Black youth. However, the psychological impact of racial discrimination on the mental health of Black youth relative to other ACEs remains underexplored. The present study aimed to address this gap by examining the extent to which racial discrimination was associated with other ACEs and elucidating the unique associations between children's experiences of racial discrimination and internalizing problems (i.e., depression, anxiety), after controlling for other ACEs. Data consisted of a subsample of Black children from the National Survey of Children's Health (N = 8,672; Mage = 9.8 years; 51.1% male). Bivariate analyses illustrated that racial discrimination was positively associated with the co‐occurrence of all other ACEs measured within the current study. Multivariable analyses using generalized linear mixed models revealed that racial discrimination was significantly associated with youth diagnoses of depression, adjusted odds ratio (aOR) = 1.35, 95% CI [1.23, 1.49], and anxiety, aOR = 1.39, 95% CI [1.31, 1.47], after controlling for other ACEs and sociodemographic covariates. The findings demonstrate that racial discrimination is comparably associated with youth internalizing problems relative to ACEs conventionally examined within the childhood trauma literature. The importance of these results, including how this knowledge can be leveraged to inform clinical practice and policy to promote the positive mental health of Black youth, are also discussed.
New Onset of Smell and Taste Loss Are Common Findings Also in Patients With Symptomatic COVID‐19 After Complete Vaccination
Authors: Vaira Luigi A. , De Vito Andrea , Lechien Jerome R. , Chiesa‐Estomba Carlos M. , Mayo‐Yàñez Miguel , Calvo‐Henrìquez Christian , Saussez Sven , Madeddu Giordano , Babudieri Sergio , Boscolo‐Rizzo Paolo , Hopkins Claire , De Riu Giacomo 
Published: November 2021

The aim of this study is to investigate the clinical profile of patients who developed coronavirus disease 2019 (COVID‐19) after full vaccination. Demographic, epidemiological and clinical data were collected through medical records and online patient‐reported outcome questionnaire from patients who developed symptomatic SARS‐CoV‐2 infection, confirmed by nasopharyngeal swab, at least 2 weeks after completion of vaccination. A total of 153 subjects were included. The most frequent symptoms were: asthenia (82.4%), chemosensory dysfunction (63.4%), headache (59.5%), runny nose (58.2%), muscle pain (54.9%), loss of appetite (54.3%), and nasal obstruction (51.6%). Particularly, 62.3% and 53.6% of subjects reported olfactory and gustatory dysfunction, respectively. Symptom severity was mild or moderate in almost all cases. Chemosensory dysfunctions have been observed to be a frequent symptom even in subjects who contracted the infection after full vaccination. For this reason, the sudden loss of smell and taste could continue to represent a useful and specific diagnostic marker to raise the suspicion of COVID‐19 even in vaccinated subjects. In the future, it will be necessary to establish what the recovery rate is in these patients.Level of Evidence4 Laryngoscope, 132:419–421, 2022