bluuebunny/crossref_metadata_2025_split huggingface dataset:
Protection Of Women Against Online-Based Shopping Fraud
Authors: Puspitosari Hervina , Fitriyah Mas Anienda Tien 
Published: October 2021

Abstract
Online shop is a popular shopping choice. attractive to consumers without having to visit the store directly, through internet applications can be easily accessed and ordered at a price offer that is sometimes also much cheaper than shopping directly coming to the store. However, the various conveniences offered in reality also cause various problems related to the protection of consumers in transactions at online shops, which oftentimes consumers also experience fraud, whether the goods have not arrived that have been ordered and paid for or the goods arrived but are not in accordance with what was ordered. There are still many cases of online buying and selling fraud, efforts are needed to reformulate existing regulations that have not been able to accommodate the interests of consumers, so it is also necessary to change the Consumer Protection Act which is more secure in providing legal protection to consumers in online buying and selling transactions as well as regulation of business actors. that adapts to the development of information technology and social changes in society.
Keywords: Protection, Women, Buying and Selling, Online
PELATIHAN TRIAS UKS PADA SISWA PETUGAS UKS SMK MUHAMMADIYAH PRINGSEWU
Authors: Vellyana Diny Vellyana , Saputri Nurwinda , Wijayanti Yossy 
Published: October 2021

Masalah kesehatan masyarakat di usia sekolah seharusnya mendapatkan perhatian khusus, karena permasalahan kesehatan pada usia sekolah sangat kompleks dan bervariasi. Seperti permasalahan kesehatan yang terjadi lebih terkait pada perilaku hidup bersih(kebiasaan cuci tangan pakai sabun,kebersihan diri, gosok gigi dan lain – lain serta gizi seimbang. Sedangkan pada anak usia SMP/MTS dan SMA/SMK/MA permasalahn yang terjadi terkait gaya hidup/perilaku berisiko terhadap kesehatan seperti konsumsi makanan, jajan. Merokok, tawuran, bullying, seks pra nikah NAPZA. Kesehatan anak sekolah ikut serta menjadi tanggung jawab sekolah melalui kegiatan kesehatan sekolah, SMK Muhammadiyah Pringsewu telah memiliki UKS yang kegiatannya belum berjalan dengan baik karena siswa petugas UKS tidak memahami terlebih dahulu tugas TRIAS UKS. Tujuan Pengabdian Masayarakat ini untuk memberikan pelatihan TRIAS UKS yaitu pendidikan kesehatan, Pelayanan kesehatan dan pembinaan lingkungan. Pelaksanaan Pengabdian Masyarakat ini dilakukan pada bulan July tanggal 19 2021 di SMK Muhamamdiyah Pringsewu Lampung dan peserta yang menjadi target adalah siswa yang telah ditunjuk oleh pihak sekolah untuk menjadi pengurus atau petugas UKS sebanyak 12 siswa. Kegiatan pelatihan petugas UKS dalam pelaksanaan TRIAS UKS yaitu, pendidikan kesehatan dan pelayanan kesehatan Metode pelatihan dilakukan dengan cara Sokratik, Demonstrasi dan Evaluasi. Capaian dari pengabdian masyarakat ini yaitu siswa mampu dan antusias dalam menerapkan program TRIAS UKS; Pelayanan kesehatan dalam menghitung IMT dan pendidikan kesehatan dengan mengetahui makanan yang bergizi bagi Remaja SMK Muhammadiyah Pringsewu Lampung. Audience atau peserta pelatihan menerapkan dan melakukan seluruh rangkaian kegiatan dengan baik
PENDIDIKAN KESEHATAN TENTANG OLAHRAGA YANG BENAR DI MASA PANDEMI COVID-19
Authors: Anastasia  
Published: October 2021

Pada akhir tahun 2019 terjadi wabah virus corona baru yang diberi nama 2019-novel corona virus (SARS-CoV-2) di kota wuhan, provinsi Hubei, China. Virus ini mulai masuk ke Indonesia pada sekitar bulan Februari 2020. Sehingga semua kegiatan termasuk olah raga harus dilakukan didalam rumah ataupun kalau di luar rumah harus dilakukan dengan cermat. Bamyak orang menganggap yang penting olah raga dengan jarak terpisah minimal satu meter dan memakai masker sudah cukup aman. Padahal tidak semua olahraga di luar ruangan itu aman. Situasi inilah yang membuat pentingnya edukasi tentang olahraga di masa pandemic. Kegiatan pengabdian masyarakat ini bermula dari surat permohonan dari ketua RW VI Kelurahan Darmo Surabaya untuk dilaksanakan penyuluhan. Kemudian surat tersebut direspon oleh unit LPPM STIKES Katolik St. Vincentius a Paulo untuk menugaskan tim dosen melakukan kegiatan pengabdian masyarakat. Seluruh proses kegiatan ini dilakukan selama 2 bulan. Setelah dilakukan proses pendidikan kesehtan didapatkan perubahan prosentase tingkat pengetahuan warga tentang olahraga yang benar dimasa pandemic covid 19 adalah 6 orang (22%) mempunyai tingkat pengetahuan baik, 11 orang (40%) mempunyai tingkat pengetahuan sedang dan 10 orang (38%) mempunyai tingkat pengetahuan kurang. Sedangkan setelah mengikuti pendidikan kesehatan didapatkan bahwa: 2 orang (7%) mempunyai tingkat pengetahuan sedang dan 25 orang (93%) mempunyai tingkat pengetahuan baik. Berdasarkan kegiatan tersebut menunjukkan bahwa pendidikan kesehatan dapat meningkatkan pengetahuan responden mengenai olah raga yang benar dimasa pandemic covid 19, disisi lain responden diharap tetap menerapkan protokol kesehatan terutama saat berolahraga di luar ruangan.
O ESPORTE BEISEBOL NAS AULAS DE EDUCAÇÃO FÍSICA NA ESCOLA PÚBLICA: UMA PRÁTICA PEDAGÓGICA (IM)POSSÍVEL À LUZ DO CURRÍCULO OFICIAL?
Authors: Queiroz Diego Faria de , Queiroz Tamara Franco Althman de 
Published: October 2021

O objetivo principal deste estudo é relatar uma prática pedagógica docente, na qual houve inserção e apresentação do esporte beisebol para os alunos do 9º ano do Ensino Fundamental durante as aulas de Educação Física (EF), em uma escola pública, seguindo as orientações do Currículo Oficial da Rede Estadual Paulista. A estrutura da unidade escolar (infraestrutura), do professor (experiência profissional), a turma (participação nas aulas) e o esporte beisebol (atividades desenvolvidas nas aulas), foram os quatro aspectos elencados para compreensão da realidade vivenciada. Falta de materiais, desmotivação dos discentes (nas atividades teóricas, principalmente) e o não entendimento da dinâmica do jogo por parte destes, foram algumas das dificuldades enfrentadas. Por outro lado, a motivação e participação nas atividades práticas foram alguns dos fatores positivos. Conclui-se que o conteúdo esporte beisebol pode ser inserido nas aulas de EF, a partir de múltiplas adaptações, e que as orientações curriculares podem contribuir para a problematização desta prática corporal nos espaços públicos de ensino.
Retinal Degeneration Associated With RPGRIP1: A Review of Natural History, Mutation Spectrum, and Genotype–Phenotype Correlation in 228 Patients
Authors: Beryozkin Avigail , Aweidah Hamzah , Carrero Valenzuela Roque Daniel , Berman Myriam , Iguzquiza Oscar , Cremers Frans P. M. , Khan Muhammad Imran , Swaroop Anand , Amer Radgonde , Khateb Samer , Ben-Yosef Tamar , Sharon Dror , Banin Eyal 
Published: October 2021

Purpose:RPGRIP1 encodes a ciliary protein expressed in the photoreceptor connecting cilium. Mutations in this gene cause ∼5% of Leber congenital amaurosis (LCA) worldwide, but are also associated with cone–rod dystrophy (CRD) and retinitis pigmentosa (RP) phenotypes. Our purpose was to clinically characterize RPGRIP1 patients from our cohort, collect clinical data of additional RPGRIP1 patients reported previously in the literature, identify common clinical features, and seek genotype–phenotype correlations.Methods: Clinical data were collected from 16 patients of our cohort and 212 previously reported RPGRIP1 patients and included (when available) family history, best corrected visual acuity (BCVA), refraction, comprehensive ocular examination, optical coherence tomography (OCT) imaging, visual fields (VF), and full-field electroretinography (ffERG).Results: Out of 228 patients, the majority (197, 86%) were diagnosed with LCA, 18 (7%) with RP, and 13 (5%) with CRD. Age of onset was during early childhood (n = 133, average of 1.7 years). All patients but 6 had moderate hyperopia (n = 59, mean of 4.8D), and average BCVA was 0.06 Snellen (n = 124; only 10 patients had visual acuity [VA] &gt; 0.10 Snellen). On funduscopy, narrowing of blood vessels was noted early in life. Most patients had mild bone spicule-like pigmentation starting in the midperiphery and later encroaching upon the posterior pole. OCT showed thinning of the outer nuclear layer (ONL), while cystoid changes and edema were relatively rare. VF were usually very constricted from early on. ffERG responses were non-detectable in the vast majority of cases. Most of the mutations are predicted to be null (363 alleles), and 93 alleles harbored missense mutations. Missense mutations were identified only in two regions: the RPGR-interacting domain and the C2 domains. Biallelic null mutations are mostly associated with a severe form of the disease, whereas biallelic missense mutations usually cause a milder disease (mostly CRD).Conclusion: Our results indicate that RPGRIP1 biallelic mutations usually cause severe retinal degeneration at an early age with a cone–rod pattern. However, most of the patients exhibit preservation of some (usually low) BCVA for a long period and can potentially benefit from gene therapy. Missense changes appear only in the conserved domains and are associated with a milder phenotype.
Open Characterization of Vaping Liquids in Canada: Chemical Profiles and Trends
Authors: Kosarac Ivana , Kubwabo Cariton , Fan Xinghua , Siddique Shabana , Petraccone Dora , He Wei , Man Jun , Gagne Matthew , Thickett Kelly R. , Mischki Trevor K. 
Published: October 2021

Currently, there is a lack of comprehensive data on the diversity of chemicals present in vaping liquids. To address this gap, a non-targeted analysis of 825 vaping liquids collected between 2017 and 2019 from Canadian retailers was conducted. Prior to mass spectrometry analysis, samples were diluted 1:500 v/v with methanol or acetonitrile. Chemical compound separation and analysis was carried out using gas chromatography and triple quadrupole mass spectrometry (GC-MS/MS) systems operated in the full scan mode and mass range of 35–450 m/z. Mass spectrum for each sample was obtained in electron ionization at 70 eV and processed. Non-targeted identification workflow included use of automated mass spectral deconvolution and identification system (AMDIS), where required, as well as a number of commercially available spectral libraries. In order to validate identities, an in-house database of expected compounds previously detected in vaping liquids was used along with genuine analytical standards for compounds of interest. This resulted in a dataset of over 1,500 unique detected chemicals. Approximately half of these chemical compounds were detected only once in a single product and not in multiple products analyzed. For any sample analyzed, on average, 40% of the chemical constituents appeared to have flavouring properties. The remainder were nicotine and related alkaloids, processing, degradation or indirect additives, natural extractives and compounds with unknown roles. Data published here from the project on the Open Characterization of vaping liquids is unique as it offers a detailed understanding of products’ flavour chemical profiles, the presence and frequency of chemicals of potential health concern, as well as trends and changes in products’ chemical complexity over a three-year period. Non-targeted chemical surveillance such as this present valuable tools to public health officials and researchers in responding to emergent issues such as vaping associated lung injury or informing chemical based strategies which may be aimed at addressing product safety or appeal.
The Long-Term Results of Three Catheter Ablation Methods in Patients With Paroxysmal Atrial Fibrillation: A 4-Year Follow-Up Study
Authors: You Ling , Zhang Xiaohong , Yang Jing , Wang Lianxia , Zhang Yan , Xie Ruiqin 
Published: October 2021

Aims: Catheter ablation of paroxysmal atrial fibrillation (PAF) has been shown to be effective and safe. However, recurrence of PAF varies between 10 and 30% for radiofrequency ablation. There have been no reports comparing long-term recurrence rates following radiofrequency ablation, cryoablation, and three-dimensional guided cryoablation plus radiofrequency ablation. The aim of this study was to observe the long-term recurrence rate of PAF when treated by these three catheter ablation methods, and to explore clinical factors that can potentially predict PAF recurrence following catheter ablation.Methods: There were 238 patients involved in this study, including 106 radiofrequency (RF) ablation cases (RF group), 66 cryoablation cases (Freeze group), and 66 cases treated by three-dimensional guided cryoablation combined with radiofrequency ablation (Freeze-plus-RF group). All patients underwent standardized follow-up. The recurrence rate of atrial fibrillation (AF) in the three groups was calculated. Predictive factors for the recurrence of AF were also investigated.Results: At 48 months (the median follow-up period), the sinus rhythm maintenance rate was 77.4% in the RF group, 72.7% in the Freeze group, and 81.8% in the Freeze-plus-RF group. The maintenance rate of sinus rhythm was highest in the Freeze-plus-RF group, but differences among the three groups were not statistically significant. Further analysis found that the preoperative left atrial appendage emptying velocity (LAAEV) (recurrence vs. no recurrence, 56.58 ± 18.37 vs. 65.59 ± 18.83, respectively, p = 0.003), left atrial (LA) anteroposterior dimension (recurrence vs. no recurrence, 36.56 ± 4.65 vs. 35.00 ± 4.37, respectively; p = 0.028), and LA vertical dimension (recurrence vs. no recurrence, 56.31 ± 6.96 vs. 53.72 ± 6.52, respectively; p = 0.035) were related to postoperative recurrence. Multiple Cox regression analysis showed that only LAAEV was predictive of postoperative recurrence of PAF (hazard ratio: 0.979; 95% confidence interval: 0.961–0.997).Conclusion: Our study found that there was no statistically significant difference in long-term recurrence rates among the RF, Freeze, and Freeze-plus-RF groups. Preoperative LAAEV is an independent predictor of postoperative recurrence of PAF.
Effect of Pre-Adsorbed Water on Methane Adsorption Capacity in Shale-Gas Systems
Authors: Chen Lei , Jiang Zhenxue , Jiang Shu , Guo Song , Tan Jingqiang 
Published: October 2021

The presence and content of water will certainly affect the gas adsorption capacity of shale and the evaluation of shale gas content. In order to reasonably evaluate the gas adsorption capacity of shale under actual reservoir conditions, the effect of water on methane adsorption capacity needs to be investigated. Taking the Da’anzhai Member of the Lower Jurassic Ziliujing Formation in the northeastern Sichuan Basin, China as an example, this study attempts to reveal the effect of pre-adsorbed water on methane adsorption capacity in shale-gas systems by conducting methane adsorption experiments in two sequences, firstly at different temperatures under dry condition and secondly at different relative humidity levels under the same temperature. The results show that temperature and relative humidity (i.e., water saturation) are the main factors affecting the methane adsorption capacity of shale for a single sample. The key findings of this study include: 1) Methane adsorption capacity of shale first increases then decreases with depth, reaching a peak at about 1,600–2,400 m. 2) Lower relative humidity correlates to greater maximum methane adsorption capacity and greater depth to reach the maximum methane adsorption capacity. 3) 20% increase of relative humidity results in roughly 10% reduction of maximum methane adsorption capacity. As a conclusion, methane adsorption capacity of shale is predominately affected by water saturation, pore type and pore size of shale. This study could provide a theoretical basis for the establishment of a reasonable evaluation method for shale adsorbed gas content.
Perioperative Multimodal General Anesthesia Focusing on Specific CNS Targets in Patients Undergoing Cardiac Surgeries: The Pathfinder Feasibility Trial
Authors: Shanker Akshay , Abel John H. , Narayanan Shilpa , Mathur Pooja , Work Erin , Schamberg Gabriel , Sharkey Aidan , Bose Ruma , Rangasamy Valluvan , Senthilnathan Venkatachalam , Brown Emery N. , Subramaniam Balachundhar 
Published: October 2021

Multimodal general anesthesia (MMGA) is a strategy that utilizes the well-known neuroanatomy and neurophysiology of nociception and arousal control in designing a rational and clinical practical paradigm to regulate the levels of unconsciousness and antinociception during general anesthesia while mitigating side effects of any individual anesthetic. We sought to test the feasibility of implementing MMGA for seniors undergoing cardiac surgery, a high-risk cohort for hemodynamic instability, delirium, and post-operative cognitive dysfunction. Twenty patients aged 60 or older undergoing on-pump coronary artery bypass graft (CABG) surgery or combined CABG/valve surgeries were enrolled in this non-randomized prospective observational feasibility trial, wherein we developed MMGA specifically for cardiac surgeries. Antinociception was achieved by a combination of intravenous remifentanil, ketamine, dexmedetomidine, and magnesium together with bupivacaine administered as a pecto-intercostal fascial block. Unconsciousness was achieved by using electroencephalogram (EEG)-guided administration of propofol along with the sedative effects of the antinociceptive agents. EEG-guided MMGA anesthesia was safe and feasible for cardiac surgeries, and exploratory analyses found hemodynamic stability and vasopressor usage comparable to a previously collected cohort. Intraoperative EEG suppression events and postoperative delirium were found to be rare. We report successful use of a total intravenous anesthesia (TIVA)-based MMGA strategy for cardiac surgery and establish safety and feasibility for studying MMGA in a full clinical trial.Clinical Trial Number:www.clinicaltrials.gov; identifier NCT04016740 (https://clinicaltrials.gov/ct2/show/NCT04016740).
Sex Differences in Case Fatality Rate of Patients With Severe Fever With Thrombocytopenia Syndrome
Authors: Zhao Jing , Lu Qing-Bin , Li Hao , Yuan Yang , Cui Ning , Yuan Chun , Zhang Xiao-Ai , Yang Zhen-Dong , Ruan Shi-Man , Liu Lan-Zheng , Du Juan , Fang Li-Qun , Liu Wei 
Published: October 2021

Background: Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne disease with high mortality. However, detailed analysis is lacking to explore the complex effect of sex with age or comorbidities.Methods: A retrospective cohort study was performed among 2,938 SFTS patients entered during 2011–2020 in Xinyang, China. The case fatality rate (CFR) was estimated for their association with sex, age, and comorbidities by an interactive way. The difference of immune response between sex was explored in an age dependent way.Results: An overall CFR of 15.3% (450/2,938) was obtained, which appeared to be higher in males than in females [17.7% vs. 13.6%, adjusted odds ratio (aOR) = 1.24; 95% CI, 1.00–1.53; P = 0.048] and increased dramatically with age (P &lt; 0.001). The associations between sex and SFTS fatal outcome were age-dependent and varied according to the status of comorbidities. The mortality-related risk conferred by older age was more pronounced in males, with aOR (95% CI) to be 5.76 (3.75–8.84) vs. 5.30 (3.54–7.95) in female. Sex-stratified analysis disclosed significant associations between death and comorbidities among female patients (aOR = 1.87, 95% CI: 1.40–2.49; P &lt; 0.001), while none among males. Among females, the significant associations between presence of comorbidity and fatal outcome differed among age groups, with aOR (95% CI) decreased from 2.28 (1.16–4.46) in ≤60 years, to 2.06 (1.34–3.18) in 60–70 years and further to 1.55 (0.97–2.47) in &gt;70 years. Altogether 194 SFTS patients were randomly selected for the test of B cells, natural killer (NK) cells, CD4 cells percentages, and anti-SFTSV IgM antibody level, the results revealed that males &gt;60 years had significantly decreased percentages of B cells, CD4 cells, lower anti-SFTSV IgM antibody titer, and increased level of NK cells than male aged ≤60 years, while none of these age specific differences was observed in the females. This finding underlies the more pronounced age specific difference in CFR among male than female.Conclusions: Males had a significantly higher mortality of SFTS than did females, and more likely to be affected by aging for SFTS mortality. This difference can be explained by the effect from comorbidities and the host immunity. It is essential to take a sex- and age-based approach to SFTS treatment and management.
Harmonisation and Between-Country Differences of the Lifetime of Experiences Questionnaire in Older Adults
Authors: Ourry Valentin , Marchant Natalie L. , Schild Ann-Katrin , Coll-Padros Nina , Klimecki Olga M. , Krolak-Salmon Pierre , Goldet Karine , Reyrolle Leslie , Bachelet Romain , Sannemann Lena , Meiberth Dix , Demnitz-King Harriet , Whitfield Tim , Botton Maëlle , Lebahar Julie , Gonneaud Julie , de Flores Robin , Molinuevo José Luis , Jessen Frank , Vivien Denis , de la Sayette Vincent , Valenzuela Michael J. , Rauchs Géraldine , Wirth Miranka , Chételat Gaël , Arenaza-Urquijo Eider M. ,   The Medit-Ageing Research Group
Published: October 2021

Background: The Lifetime of Experiences Questionnaire (LEQ) assesses complex mental activity across the life-course and has been associated with brain and cognitive health. The different education systems and occupation classifications across countries represent a challenge for international comparisons. The objectives of this study were four-fold: to adapt and harmonise the LEQ across four European countries, assess its validity across countries, explore its association with brain and cognition and begin to investigate between-country differences in life-course mental activities.Method: The LEQ was administered to 359 cognitively unimpaired older adults (mean age and education: 71.2, 13.2 years) from IMAP and EU-funded Medit-Ageing projects. Education systems, classification of occupations and scoring guidelines were adapted to allow comparisons between France, Germany, Spain and United Kingdom. We assessed the LEQ's (i) concurrent validity with a similar instrument (cognitive activities questionnaire - CAQ) and its structural validity by testing the factors' structure across countries, (ii) we investigated its association with cognition and neuroimaging, and (iii) compared its scores between countries.Results: The LEQ showed moderate to strong positive associations with the CAQ and revealed a stable multidimensional structure across countries that was similar to the original LEQ. The LEQ was positively associated with global cognition. Between-country differences were observed in leisure activities across the life-course.Conclusions: The LEQ is a promising tool for assessing the multidimensional construct of cognitive reserve and can be used to measure socio-behavioural determinants of cognitive reserve in older adults across countries. Longitudinal studies are warranted to test further its clinical utility.