bluuebunny/crossref_metadata_2025_split huggingface dataset:
no processo artístico de criação nas artes plásticas
Authors: Monteiro Ilda 
Published: September 2021

O presente estudo, tendências no processo artístico de criação nas artes plásticas, pretende trasmitir o conhecimento da temática, com características específicas e diversificadas que se completam entre si. Na criação pictórica, a ação do artista modifica a obra em várias fases, que se finalizam a partir de questões, que por sua vez, respondem à experiência do criador.
Na área das artes plásticas os procedimentos criativos também estão relacionados com o momento histórico, aspectos sociais, culturais e tecnológicos em que o artista se insere. O principal objetivo do estudo é a análise das técnicas e os resultados no processo criativo, tendo como base a produção do artista, que tiveram um papel construtivo e expressivo e condicionaram o resultado estético / plástico da obra, à semelhança de qualquer outra tecnologia utilizada para determinado objecto artístico. Este trabalho apresenta métodos e técnicas das tendências verificadas a partir da exploração do artista, o qual questiona todo o processo criativo da obra. O ready-made duchampiano surge como concretização, reavalia o papel do artista e o modo como este interage com o objecto artístico, com as instituições e com o público especializado de encontro à contemporaneidade da arte.
Evidence-based teaching practices: A road less traveled in Pakistan?
Authors: Iqbal Zafar 
Published: September 2021

It is no secret that most health professionals, after postgraduation, aim to secure an academic position in a teaching institute due to various personal and/or professional preferences. Personal interest in teaching, inspirational figure/ role model-driven career selection, fixed working hours, financial rewards, societal respect, and relatively easier career path are some of the prominent motives for health professionals to join academia (Huda & Yousuf, 2006). Indeed, it is a personal choice of a health professional should he/she opt for an academic career path. However, a serious question to ask oneself is: Am I prepared and ready for this challenging role?
Does criminal law fall within the power of genetics? (difficult answers on complex questions)
Authors: Козаченко Иван Яковлевич 
Published: September 2021

В данной статье сделана попытка найти ответы на важные по своей сути вопросы относительно того: насколько глубоко и масштабно геном человека своим влиянием охватил объем его организма; познаваемы ли происходящие в организме человека процессы с участием его генома; допустимы ли манипуляции с генетическим материалом и имеют ли они разумные пределы; нравственно ли с помощью уголовно-правового механизма: а) вводить уголовно-правовые запреты на определенные манипуляции с генетическим материалом и б) устанавливать защитные заслоны, позволяющие оградить перспективные в социальном плане и полезные с позиции медицинской науки и практики мероприятия от любых незаконных, а тем более преступных посягательств? При попытке найти хотя бы толику ответов на поставленные (и не только) вопросы предвосхищает суждение о том, что человек вообще - это тайна природы за семью печатями. Тем более густая пелена загадочной завесы нисколько не проясняется даже на самом отдаленном расстоянии от решения практически значимых проблем генетического сканирования человека. Естественно, что в чреде вопросов, ответы на которые можно и нужно находить ответы, особое место занимает тот, который лег в основу названия данной статьи: подвластно ли уголовное право генетике?
The article attempts to give an answer to the substantial questions: what is the scope of genome influence on human organism; are we able to learn the nature of the genome-initiated processes ongoing in it; are human genetic manipulations admissible and do they have reasonable limits; is it moral to use criminal mechanics to: a) establish criminal law prohibitions for certain genetic manipulations and b) establish “shields” aimed to cover socially perspective and medically useful technologies from any illegal and much more criminal intrusions? While trying to find a suitable answer on the questions above, it becomes clear that human itself is a closed book of nature. Moreover, the shroud of secrecy doesn’t lift even when people trying to solve practically significant human genetic scanning problems.
Community-Based Interventions and Behaviors of HIV+ Persons in Congo-Kinshasa
Authors: Ebengho-Bokelo Max , Super-Eloko Jeremy 
Published: September 2021

Introduction: Sub-Saharan African communities bear the highest burden of HIV/AIDS in the world. Because of identifiable cultural links and local beliefs, people are more likely to engage in sexual mores that could negatively impact their life. Starting in early 2000, Congolese HIV+ patients have undergone a variety of medico-social inputs designed to decrease risky behaviors among people in the program and their family members.
Goals: This inquiry aimed to understand how PLWHs assess the influence of community-based incentives within their society, as primarily conceived to improve daily behaviors of each person living with HIV (PLWH), and a few selected family members with unknown HIV-serostatus.
Methods: From December 2020 to March 2021, a cross-sectional study was engaged to gather qualitative-driven information from nine in-depth interviews, three focus groups, and two key-informant interviews. Changes were self-assessed through data gotten from 2004-2014 in sexual cleansing, levirate and sororate marriage, Kintwidi phenomenon, stigma and discrimination, sexual gender-based violence (SGBV) and female genital mutilation (FGM), unprotected receptive vaginal or anal intercourse, and behavioral rejection of condoms throughout a decade of Congolese Community-based Interventions (CBIs) implemented from 2004. Grounded on the socioecological model (SEM), this ethnographic study was based on the meaning of the influence of CBIs on cultural behaviors among PLWHs for HIV/AIDS prevention purposes.
Results: Data from Kinshasa and Bandundu were coded and analyzed through NVivo R1 and Excel, showing significant negative sentiments for all eight key-cultural components in PLWHs.
Conclusion: Out of the holistic approach employed to tackle HIV/AIDS in communities, the comprehensive strategy enabled for social change in Congo-Kinshasa brought specific impactful insights in terms of behavior according to interviewed PLWHs. Findings could be used to inform further preventive activities to alleviate any community HIV burden in sub-Saharan Africa.
Analysis and Identification of Damages Caused by Canine (Canis lupus familiaris) Manipulation of Woven Textiles as Cultural Evidence in Forensic Cases
Authors: Molina Gabriela , De Luca Stefano , Scarso Fabiana 
Published: September 2021

Scavenging of human remains by dogs can make the process of identification and analysis of perimortem trauma difficult. Numerous scientific studies have been published about the damage caused to osseous remains by dogs due to postmortem consumption orlethal attacks. However, few studies deal with the issue of the analysis of clothing associated with human remains.
The purpose of this investigation was to identify patterns of damage caused by domestic dogs to commonly used, woven textiles. Forty-five cloth bags were used (20 × 30 cm each), made by hand with three different types of woven textile (15 of each textile): stretch(polyester with elastic), denim, and polyester, with a thickness of 40.84, 57.95, and 31.46 threads per cm², respectively. The canine sample consisted of 15 dogs, differing in size, age, and sex, coming from the “Fundación Chile Mestizo,” in Santiago, Chile. Through analysis of variance, researchers examined the relationship between the type of textile and presence of damage, and later, they calculated the frequency of damage according to type of textile. The statistical program Minitab 19 was used to do this. According to the results, four types of patterns were identified: puncture and mastication, present in 62% and 75% of the cases, respectively; perforation; and “hole and tear” damage in 91% of the analyzed cases. Regarding the relationship between textile type and frequency of damage, researchers found that the thickness and weight of the textile are directly connected to the type of damage.
Detection of Corynebacterium kroppenstedtii in Granulomatous Lobular Mastitis Using Real-Time Polymerase Chain Reaction and Sanger Sequencing on Formalin-Fixed, Paraffin-Embedded Tissues
Authors: Tariq Hamza , Menon Preethi D. , Fan Hongxin , Vadlamudi Kumari V. , Pandeswara Sri Lakshmi , Nazarullah Alia N. , Mais Daniel D. 
Published: September 2021

Context.—
Associations between granulomatous lobular mastitis (GLM) and Corynebacterium kroppenstedtii have been reported since 2002, but large-scale studies to assess the actual prevalence of this bacterium in GLM have not been performed.

Objective.—
To assess the prevalence of C kroppenstedtii in GLM using real-time polymerase chain reaction and Sanger sequencing.

Design.—
We analyzed formalin-fixed, paraffin-embedded tissues from 67 cases of GLM by sequential DNA amplification and sequencing to assess the rate of C kroppenstedtii detection in GLM. A retrospective analysis including patient demographics, history of pregnancy and lactation, clinical signs and symptoms, radiographic findings, histologic pattern, Gram stain results, and microbial cultures was performed on 67 cases of GLM. In addition, 10 cases of nongranulomatous breast abscess were included as controls.

Results.—
C kroppenstedtii 16S rRNA SYBR real-time polymerase chain reaction was positive on formalin-fixed, paraffin-embedded tissues from 46 of 67 (68.7%) GLM cases, while all control cases were negative. Among the positive cases, the majority showed features of cystic neutrophilic granulomatous mastitis.

Conclusions.—
C kroppenstedtii was highly prevalent in GLM cases and was not found to be associated with nongranulomatous breast abscess in our study (P &lt; .001).
Sequential Development of JAK2V617F Mutation and BCR-ABL1 Fusion in Individual Patients With Myeloproliferative Neoplasms
Authors: Zhao Yue , Reddi Deepti , McCracken Jenna , Iranzad Natasha , Rehder Cathrine , Neff Jadee , Wang Endi 
Published: September 2021

Context.—
Concomitant BCR-ABL1 and JAK2V617F in myeloproliferative neoplasms (MPNs) is rare, and its pathogenesis and clinical significance are unclear.

Objective.—
To investigate the clonal relationship between the 2 genomic alterations, as well as the clinicopathologic impact.

Design.—
Retrospective analysis of MPNs with sequential development of BCR-ABL1 and JAK2V617F.

Results.—
Of 6 cases, 5 had JAK2V617F-positive MPN diagnosed before acquiring BCR-ABL1 years later, and 1 had BCR-ABL1+ chronic myeloid leukemia before JAK2V617F-positive myelofibrosis completely replaced the BCR-ABL1+ clone 1 year after tyrosine kinase inhibitor therapy. Among the former group, treatment for the initial MPN involved hydroxyurea, ruxolitinib, and/or supportive care, and the latency to the development of JAK2V617F ranged from 4 to 13 years (median of 9 years). Four cases showed retention of JAK2V617F, whereas BCR-ABL1 emerged as the major clone, including 2 cases that exhibited parallel increases in JAK2V617F and BCR-ABL1 burdens, with both genomic markers exceeding 50%. Three patients received stem cell transplants and demonstrated sustained engraftment, with the genomic markers below detectable levels.

Conclusions.—
Most MPNs with concomitant JAK2V617F and BCR-ABL1 are actually composite MPNs with a “second hit” residing on a different clone. Rare cases demonstrate a subclone harboring a “double-hit” in a background of a JAK2V617F-positive stem line clone. The probability of a “double-hit” with a BCR-ABL1+ stem line clone is probably reduced by effective tyrosine kinase inhibitor treatment. The treatment often involves combined kinase inhibitors and/or hydroxyurea, but the outcome is unpredictable; hematopoietic stem cell transplantation may be the ultimate therapeutic option for this complicated disease.
Independent validation of downscaled climate estimates from a coastal Alaska watershed using local historical weather journals
Authors: Williamson Emily R. , Sergeant Christopher J. 
Published: September 2021

Downscaling coarse global and regional climate models allows researchers to access weather and climate data at finer temporal and spatial resolution, but there remains a need to compare these models with empirical data sources to assess model accuracy. Here, we validate a widely used software for generating North American downscaled climate data, ClimateNA, with a novel empirical data source, 20th century weather journals kept by Admiralty Island, Alaska homesteader, Allen Hasselborg. Using Hasselborg’s journals, we calculated monthly precipitation and monthly mean of the maximum daily air temperature across the years 1926 to 1954 and compared these to ClimateNA data generated from the Hasselborg homestead location and adjacent areas. To demonstrate the utility and potential implications of this validation for other disciplines such as hydrology, we used an established regression equation to generate time series of 95% low duration flow estimates for the month of August using mean annual precipitation from ClimateNA predictions and Hasselborg data. Across 279 months, we found strong correlation between modeled and observed measurements of monthly precipitation (ρ = 0.74) and monthly mean of the maximum daily air temperature (ρ = 0.98). Monthly precipitation residuals (calculated as ClimateNA data - Hasselborg data) generally demonstrated heteroscedasticity around zero, but a negative trend in residual values starting during the last decade of observations may have been due to a shift to the cold-phase Pacific Decadal Oscillation. Air temperature residuals demonstrated a consistent but small positive bias, with ClimateNA tending to overestimate air temperature relative to Hasselborg’s journals. The degree of correlation between weather patterns observed at the Hasselborg homestead site and ClimateNA data extracted from spatial grid cells across the region varied by wet and dry climate years. Monthly precipitation from both data sources tended to be more similar across a larger area during wet years (mean ρ across grid cells = 0.73) compared to dry years (mean ρ across grid cells = 0.65). The time series of annual 95% low duration flow estimates for the month of August generated using ClimateNA and Hasselborg data were moderately correlated (ρ = 0.55). Our analysis supports previous research in other regions which also found ClimateNA to be a robust source for past climate data estimates.
Seagrass contribution to blue carbon in a shallow karstic coastal area of the Gulf of Mexico
Authors: Cota Lucero Tania C. , Herrera-Silveira Jorge A. 
Published: September 2021

Seagrass meadows provide multiple ecosystem services, including carbon sequestration. However, seagrass meadows are among the most threatened ecosystems worldwide. Determining the magnitude of the carbon stocks in seagrass meadows at the regional scale allows for the estimation of their global magnitude and identification of their importance in regional environmental mitigation strategies. The objective of the present study was to determine the structure of seagrass meadows in the Los Petenes Biosfera Reserve (LPBR) and evaluate their contributions to sinks of carbon in this system, located in Yucatan, which is considered the region with the largest seagrass extension in Mexico. Analyses of the seagrass meadows were executed following standardized protocols (spectral analysis, and isotope and carbon stock analyses). The LPBR stores an average of 2.2 ± 1.7 Mg C ha−1 in living biomass and 318 ± 215 Mg C ha−1 in sediment (top 1 m), and this carbon stock decreases with water depth. The seagrass community extends 149,613 ha, which represents the largest organic carbon stock (47 Tg C) documented in seagrass meadows in Mexico. Macroalgae and seagrass represent 76% of the organic carbon stored in sediment. If LPBR seagrass meadows are lost due to natural or anthropogenic impacts, 173 Tg CO2eqemissions could be released, which corresponds to the emissions generated by fossil fuel combustion of 27% of the current Mexican population. This information emphasizes the importance of seagrass meadows as a carbon sink in the region and their contribution to climate change mitigation, thus allowing for the implementation of necessary conservation strategies.
Screening of Genotypes against Major Sucking Insect- Pests of Mothbean [Vigna aconitifolia] in Arid Region
Authors: Naga K. L. , Naqvi A. R. , Naga B. L. , Deshwal H. L. , Jhumar L. 
Published: September 2021

Aim: Some genotypes of mothbean were screened for their comparative preference against jassids, whiteflies and thrips.
Materials and Methods: The experiment was laid out during Kharif season in Randomized Block Design with three Replications. Ten genotypes (viz., RMO-225, RMO-40, RMO-423, RMO-435, RMO-257, RMO-25, RMO-141, RMO-20-36, RMO-04-01-28 and RMO-28-80) were screened against major sucking insect pests which were replicated thrice.
Observations: The observations were recorded after two weeks of sowing at weekly intervals after two weeks of sowing. The pest populations were recorded on five randomly selected and tagged plants per plot in early hours when insect have minimum activity.
Results: The data revealed that none of the genotypes ware found free from sucking insect pest attack. On the basis of peak population, the genotypes RMO-25 and RMO-141 were categorized as least preferred to jassids, whiteflies and thrips, whereas, RMO-435, RMO-225 and RMO-04-01-28 as highly preferred to jassids and whiteflies and RMO-435, RMO-225 and RMO-257 as highly resistant to thrips.
Conclusion: It is well known that certain genotypes of crops are less attacked by a specific insect-pest than others because of natural resistance. In the integrated pest management programme, growing of varieties (RMO-25 and RMO-141) with less preference to sucking insect-pests is one of the most important tools without additional cost.
Convalescent Plasma for COVID-19- is it Time to Say Goodbye? A Single-Center, Retrospective, Observational Study from Northern India
Authors: Setia Rasika , Dogra Mitu , Thangavel Gokhula Prasath , Yadav Ramesh , Rahman Amena Ebadur , Bhasin Atul , Pande Rajesh Kumar , Nayar Sandeep , Singal R. K. , Vardani Anil , Pande Deepak Gargi , Saini R. N. , GulatI Tribhuvan , Singh Vivek Pal , Kalra Sunny , Anand Gagan , Garg Manish , Ghai Santosh , Agarwal N. M. 
Published: September 2021

Background: COVID-19 pandemic continues threatening the world with no effective treatment to tackle the menace. Till date, there is conflicting evidence on efficacy of CP in reducing COVID-19 related mortality. The objective of this study was to see disease progression and 7, 14 and 28-day mortality after CP therapy and analyze CP efficacy with/without Remdesivir.
Materials and Methods: A retrospective single-centre observational study done from August 20, 2020, to 20 November 2020. Records of 294 COVID-19 patients with moderate to severe disease given CP therapy were analysed based on disease progression and length of hospital stay, further subcategorized on age, clinical profile, risk factors, ward/ICU, ventilatory support and co-administration of Remdesivir.
Results: Lowest 7-day mortality rate was seen within age group 20-40 years (0%) and was highest in ≥61 years (24.3%). 87 patients on ventilatory support showed higher 28day mortality (48.28%) compared to non-ventilated (10.14%), (P<0.00001). Lesser 7-day mortality was seen in early CP therapy ≤3 days of admission (P=0.01). Patients requiring ICU admission showed higher 14 and 28-day mortality compared to ward P=0.001%). Median (IQR) length of hospital stay from CP transfusion was shorter, 4 (3 to 9) days in group 2 (CP only) compared to 7 (4 to 12) days in group1 (CP+Remdesivir ).
Conclusion: CP therapy in ≤3 days of hospital admission in COVID-19 patients with moderate to severe infection not on ventilatory support showed reduction in mortality and length of hospital stay. Length of hospital stay was shorter in the CP-only group as compared to the CP+ Remdesivir group.
“Homoeopathic Perspective of Attention Deficit Hyperactivity Disorder - Hyperactive Type – A Review”
Authors: Gnnanaprakasham M. , Mathew Sunny , Mohan N. D. 
Published: September 2021

Attention Deficit Hyperactivity Disorder (ADHD) is commonly diagnosed neuropsychiatric condition affecting the children and adolescence. Nearly 8 percent of school - going children were diagnosed as ADHD and mostly as hyperactive type. More than 60 percent of children with ADHD were progressed to grow with the symptoms into adulthood which causes significant impaired academic achievements, poor interpersonal skills, disordered social activities, and various psychiatric disorders like learning disability, substance abuse, mood disorders, disruptive behavior disorder, etc., Homoeopathy a unique system of medicine which provides a beneficial effect on the human body through its ultra-diluted and potentized drug substances adopting holistic approach. There are reliable sources where homoeopathy proves its efficacy in treating ADHD children. This article provides a cluster of remedies derived through repertorisation considering only the symptoms of ADHD hyperactive type which will be helpful in cases where the individualization of the child is difficult to achieve. Considering the symptomatology of ADHD hyperactive type mentioned in DSM V criteria the most indicated remedies among various remedies were Medorrhinum, Nux. Vom, Carcinosinum, Hyoscyamus, Anacardium, Chamomilla, Veratrum. Album, Coffea Cruda, Tarentula etc.
Effects of Proton Pump Inhibitors on Serum Calcium Level: A Study on Rabbit Model
Authors: Memon Rizwan Ahmed , Memon Fazeela Rizwan , Memon Ali Raza , Memon Jamshaid Ul Qadir , Laghari Jawaid Hussain , Shams Salman , Memon Ashfaq Rahim 
Published: September 2021

Background: Proton Pump inhibitors (PPI) are widely used all over the world as therapeutic agents as well as prophylactic agent at different age groups for multiple gastrointestinal disorders etc. it inhibits the hydrogen potassium pump (H/K ATPase Pump). PPI interferes the calcium absorption and thus disturbs acid secretion which leads to decrease the calcium level in the body.
Objective: The present design is to evaluate the effects of PPI on serum calcium level in rabbit model.
Study Design: Randomized Control Trial/ Study on Rabbit Model.
Place and Duration of Study: This experimental study was done at Department of Pharmacology Isra Medical University Hyderabad (November 2020 to March 2021
Material & Methods: A total 20 healthy male rabbits with weight between 1-2kg were included in this study. While female rabbits, ill rabbits and rabbits with weight less than 1kg were excluded from study. Ten rabbits were given omeprazole sachet of 20mg orally dissolve in water once a day and 10 rabbits were given sachet of esomeprazole of 20mg dissolve in water once a day upto 90 days regularly. At different levels of study blood samples were obtained from vein near ear of rabbits and samples were centrifuged for 10minutes to obtain the serum. Then serum was sent to Isra Diagnostic Laboratory for analysis of serum calcium levels of all samples at different levels of study.
Results: Serum calcium levels of all rabbits were analyzed at three different levels of study, at zero level before starting of experiment, at level I after completion of one month of experiment and level II after the completion of three months of experiment. The normal serum calcium level in rabbits is 13-15mg/dl.8There was a significant decline in serum calcium level in Group A (Omeprazole Group), while in Group B (Esomeprazole Group) there was no significant relation between decreased serum calcium levels.
Conclusion: The study concluded that there is significant relation of longterm usage of PPI on serum calcium level.