bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concordantia Veteris et Novi Testamenti in the Mosaic of the Funerary Basilica of Via Dottor Consoli in Catania
Authors: DI CARO Dominique Maria 
Published: October 2021

In 1930, it was discovered in the area of Via Dottor Consoli, in the northwestern sector of current urban centre of Catania, a cemetery complex used from the Hellenistic to the Byzantine era, by the Superintendence of Antiquities of Syracuse, under the direction of then Inspector G. Libertini. In that occasion, portions of the perimeter strip of a floor mosaic inside the basilica were brought to light, which during later excavation campaigns was completely excavated and detached in 1957 to be exhibited in the “salone di San Giorgio” of the Castello Ursino. Currently, it is kept in the storerooms of the ex-Manifattura Tabacchi (site of the future Regional Interdisciplinary Museum of Catania).
The mosaic of the basilica nave, dated to the middle of the sixth century AD, represents common secular themes on three registers: running felids, animals in combat and the marine scene with two men on a boat in front of a dragon with red coat dotted with white eyelets. In a panel there is a snake twisted around the trunk of a tree, in my opinion, to be identified with the Tree of knowledge mentioned by the sacred texts. In the Apocalypse, “the old serpent, which is called the Devil and Satan, the deceiver of the whole world” (Revelation 12, 9) becomes a great red dragon, who appears in the marine scene. An interpretative reading of the mosaic is proposed in the light of the rhetorical procedure of “significant inclusion” to enhance the unity and narrative continuity between the Old and New Testament.
Preclinical Researches of Vitamin D Role in Preventing Malignant Diseased, a Systematic Review
Authors: Udristioiu Aurelian , Farmazon Iulia , Cojocaru Manole 
Published: October 2021

ABSTRACT

Background:
In general, the role of vitamin D, [25 (OH)D], is to regulate calcium and phosphate metabolism by bone remodeling but the studies, in the recent decades, shown that low exposure at the sun and vitamin D deficiency are associated with the increased risk of many other extra-skeletal disorders, such as cancer diseases.

Content:
Several original studies and meta-analyses have evaluated the role of vitamin D in cancer prevention or the potential to improve cancer treatment outcomes. The broad field of antitumor effects of calcitriol and analogues in the treatment of cancer, as single agents or in combination with other anticancer agents, is mainly based on the mechanisms of inhibition of cancer cell proliferation and invasiveness, induction of differentiation, apoptosis and the promotion of angiogenesis.

Summary and Outlook:
The scientific evidence suggests that the provider of health care should consider the increasing of concentrations of 25 (OH) D through sun exposure or by supplementing with vitamin D of people with different ages to reduce the risk ills with Vitamin D deficiency besides the standard treatment of some chronic diseases, inclusive cancer disease beside the specific personalized antineoplastic treatments for every malignant disease.
Comparison Among Three Estimation Methods to Estimate Cascade Reliability Model (2+1) Based On Inverted Exponential Distribution
Authors: Hamza Raheem Sairan 
Published: October 2021

In this paper, we are mainly concerned with estimating cascade reliability model (2+1) based on inverted exponential distribution and comparing among the estimation methods that are used . The maximum likelihood estimator and uniformly minimum variance unbiased estimators are used to get of the strengths and the stress ;k=1,2,3 respectively then, by using the unbiased estimators, we propose Preliminary test single stage shrinkage (PTSSS) estimator when a prior knowledge is available for the scale parameter as initial value due past experiences . The Mean Squared Error [MSE] for the proposed estimator is derived to compare among the methods. Numerical results about conduct of the considered estimator are discussed including the study of mentioned expressions. The numerical results are exhibited and put it in tables.
Quelques points concernant la relation entre les normes juridiques et les normes éthiques dans la vie universitaire roumaine
Authors:   Facultatea de Drept a Universității din București, CONSTANTINESCU-MĂRUNȚEL Cătălin 
Published: October 2021

": In this paper we are beginning our research by underlining the essential characteristics of a legal norm, particularly those that one does not find in the case of other types of norms. Thereafter, we are examining the mechanisms employed by a legal system which allow the cohabitation and the collaboration between the two species that we are addressing: the legal norms and the ethical norms. In order to have a complete overview of the matter, we are utilising a few comparisons, relying on similar examples from other fields of study. We are researching under which conditions one may employ legal sanctions in cases where an ethical norm has been violated.	These being covered, we can continue by analysing the ethical (or deontological) codes used by the Romanian universities. For reasons of conciseness, we are limiting our scope to the documents adopted by the University of Bucharest. This can be done as this organisation functions on the basis of a legal and ethical normative architecture which is representative for the Romanian academic environment.	In place of conclusions, we are making a few proposals for the improvement of these codes. We are hoping that we are thus contributing to the evolving ethical culture in the Romanian universities."
‘Ulama’ Tiga Serangkai’ and Their Contribution towards Reviving Islamic Education in the Early Post-Colonial Indonesia (Sumbangan Ulama’ Tiga Serangkai dalam Menghidupkan Semula Pendidikan Islam di Indonesia pada Awal Pasca-Kolonial)
Authors: Ahmad Nadzrah 
Published: October 2021

Ulama’ Tiga Serangkai of North Sumatera was a name coined for three distinguished scholars of the Malay World for their many contributions in the area of Islamic Studies. Abdul Halim Hasan, Zainal Arifin Abbas and Abdul Rahim Haitami received the title of Ulama’ Tiga Serangkai for their collective work of Tafsīr al-Qur’ān al-Karīm. They envisioned towards reviving Islamic understanding among the Malays of post-colonial era. Apart from the Qur’ānic commentary, these three figures offered their Malay Muslim readers a collection of knowledge on Islam in Malay language. Their writings were on faith (’īmān), practices (ʿibādah), theology (tawḥīd) as well as on reformation and modernisation. This paper attempts to highlight works done by the Ulama’ Tiga Serangkai and examine their nature of contribution towards reviving Islamic knowledge and education among the Muslims of the era. The finding shows that the three had numerous contributions in terms of published and written works in the area of Islamic studies. Among the three, Abdul Halim Hasan was known to have significantly contributed in restructuring Islamic schools and education in the attempt to prevent unwelcomed interventions from the colonial authority.
Keywords: Ulama’ Tiga Serangkai, Contributions towards Islamic Education, Dutch Policy towards Education, Islamic Reformism.
Abstrak
Ulama’ Tiga Serangkai adalah gelaran bagi tiga tokoh terkemuka dari Sumatera Utara atas sumbangan mereka dalam bidang Pendidikan Islam. Abdul Halim Hasan, Zainal Arifin Abbas dan Abdul Rahim Haitami mendapat gelaran ini untuk karya kolektif mereka iaitu Tafsir al-Qur’an al-Karim. Aspirasi mereka adalah menghidupkan kembali kefahaman Islam di kalangan orang-orang Melayu pada era pasca-penjajahan. Selain daripada tafsiran Al-Qur'an, ketiga-tiga tokoh ini juga mengenengahkan koleksi pengetahuan Islam dalam bahasa Melayu kepada pembaca rantau ini. Tulisan-tulisan mereka berkisar tentang isu iman, ibadah, teologi (tawhid) serta isu reformasi dan modenisasi. Artikel ini memberi tumpuan kepada karya-karya hasil Ulama’ Tiga Serangkai dan mengkaji nilai sumbangan mereka dalam menghidupkan kembali pengetahuan dan pendidikan Islam di kalangan umat Islam pada zaman itu. Hasil kajian ini menunjukkan bahawa ketiga tokoh ini menghasilkan sumbangan yang tinggi nilainya dari segi karya terbitan dan tulisan dalam bidang pendidikan Islam. Di antara ketiga mereka, Abdul Halim Hasan merupakan tokoh yang banyak memberikan sumbangan besar dalam menyusun semula sekolah dan pendidikan Islam dalam usaha membendung campur tangan pihak berkuasa penjajah.
Kata Kunci: Ulama’ Tiga Serangkai, Sumbangan terhadap Pendidikan Islam, Polisi Kerajaan Belanda terhadap Pendidikan Islam, Reformasi Islam.
Secondary syphilis with ocular involvement in a HIV-infected patient – case report
Authors: Olszewska AM , Reduta T , Bacharewicz-Szczerbicka J , Flisiak I 
Published: October 2021

<p><strong>ABSTRACT</strong><br />We describe the case of a HIV-infected patient, in whom a secondary syphilis with skin lesions and ocular involvement developed.<br />On admission papular skin rash and partial visual loss with left eye were observed. Serological tests for syphilis were positive in very high titers. Ophthalmological examination revealed ocular abnormalities indicating ocular syphilis. Cerebrospinal fluid (CSF) tests showed elevated concentration of immunoglobulin G (IgG) with normal white blood count and albumin concentration, serological treponemal tests for syphilis were positive. <br />Intravenous therapy with Penicillinum Crystallisatum (Benzylpenicillinum kalicum) was administered, according to the neurosyphilis treatment schedule, achieving resolution of the skin lesions and partial vision improvement, a month after the end of the treatment a complete recovery of the vision was noted. Serological tests` for syphilis titers decreased fourfold.<br />Described case confirms reasonability of examination for syphilis in patients with sudden vision disturbances, especially those HIV-infected. It also indicates that early appropriate treatment of the ocular syphilis prevents permanent loss of vision.</p>
<p><strong>STRESZCZENIE</strong><br />Prezentujemy przypadek chorego zakażonego HIV, u którego wystąpiła kiła wczesna nawrotowa z objawami skórnymi i zajęciem narządu wzroku.<br />Przy przyjęciu stwierdzono osutkę grudkową i częściową utratę widzenia lewym okiem. Kiłowe odczyny serologiczne były dodatnie o bardzo wysokich mianach. Badanie okulistyczne wykazało odchylenia mogące odpowiadać kile narządu wzroku. W płynie mózgowo-rdzeniowym (PMR) stwierdzono podwyższone stężenie immunoglobuliny G (IgG) przy prawidłowej cytozie i stężeniu albumin oraz dodatnie kiłowe odczyny krętkowe.<br />Wdrożono leczenie penicyliną krystaliczną dożylnie, według schematu leczenia kiły ośrodkowego układu nerwowego (OUN). Uzyskano ustąpienie zmian skórnych i częściową poprawę widzenia, po miesiącu od zakończenia leczenia całkowity powrót widzenia. Miana kiłowych odczynów serologicznych uległy czterokrotnemu obniżeniu.<br />Opisywany przypadek potwierdza zasadność diagnostyki w kierunku kiły u osób z nagłymi zaburzeniami widzenia, zwłaszcza u pacjentów zakażonych HIV. Wskazuje również, że odpowiednio szybkie podjęcie adekwatnego leczenia pomaga zapobiec trwałej utracie wzroku.</p>
Pengaruh Pelatihan, Motivasi Dan Budaya Organisasi Terhadap Kinerja Karyawan Pada PT Bank Mandiri, Tbk Di Jakarta
Authors: Wicaksono Widhi , Suyatin Suyatin , Sunarsi Denok , Affandi Azhar , Herling Herling 
Published: October 2021

Penelitian ini bertujuan untuk mengetahui pengaruh pelatihan, motivasi dan budaya organisasi terhadap kinerja karyawan pada PT. Bank Mandiri, Tbk di Jakarta. Metode yang digunakan adalah explanatory research dengan teknik analisis menggunakan analisis statistik dengan pengujian regresi, korelasi, determinasi dan uji hipotesis. Hasil penelitian ini pelatihan berpengaruh signifikan terhadap kinerja karyawan sebesar 37,0%, uji hipotesis diperoleh t hitung > t tabel atau (7,533 > 1,984). Motivasi berpengaruh signifikan terhadap kinerja karyawan sebesar 42,1%, uji hipotesis diperoleh t hitung > t tabel atau (8,499 > 1,984). Budaya organisasi berpengaruh signifikan terhadap kinerja karyawan sebesar 37,1%, uji hipotesis diperoleh t hitung > t tabel atau (7,597 > 1,984). Pelatihan, motivasi dan budaya organisasi secara simultan berpengaruh signifikan terhadap kinerja karyawan dengan persamaan regresi Y = 6,746 + 0,243X1 + 0,304X2 + 0,370X3. Kontribusi pengaruh sebesar 55,5%, uji hipotesis diperoleh F hitung > F tabel atau (39,934 > 2,470).
Bioinformatics Analysis Using ATAC-seq and RNA-seq for the Identification of 15 Gene Signatures Associated With the Prediction of Prognosis in Hepatocellular Carcinoma
Authors: Yang Hui , Li Gang , Qiu Guangping 
Published: October 2021

BackgroundGene expression (RNA-seq) and overall survival (OS) in TCGA were combined using chromosome accessibility (ATAC-seq) to search for key molecules affecting liver cancer prognosis.MethodsWe used the assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) to analyse chromatin accessibility in the promoter regions of whole genes in liver hepatocellular carcinoma (LIHC) and then screened differentially expressed genes (DEGs) at the mRNA level by transcriptome sequencing technology (RNA-seq). We obtained genes significantly associated with overall survival (OS) by a one-way Cox analysis. The three were screened by taking intersection and further using a Kaplan–Meier (KM) for validation. A prognostic model was constructed using the obtained genes by LASSO regression analysis.The expression of these genes in hepatocellular carcinomas was then analysed. The protein expression of these genes was verified using the Human Protein Atlas(HPA) online datasets and immunohistochemistry.ResultsATAC-seq, RNA-seq and survival analysis, combined with a LASSO prediction model, identified signatures of 15 genes (PRDX6, GCLM, HTATIP2, SEMA3F, UCK2, NOL10, KIF18A, RAP2A, BOD1, GDI2, ZIC2, GTF3C6 SLC1A5, ERI3 and SAC3D1), all of which were highly expressed in hepatocellular carcinoma. The LASSO prognostic model showed that this risk score had high predictive accuracy for the survival prognosis at 1, 3 and 5 years. A KM curve analysis showed that high expression of all 15 gene signatures was significantly associated with a poor prognosis in LIHC patients. HPA analysis of protein expression showed that PRDX6, GCLM, HTATIP2, NOL10, KIF18A, RAP2A and GDI2 were highly expressed in the hepatocellular carcinoma tissues compared with normal control tissues.ConclusionsPRDX6, GCLM, HTATIP2, SEMA3F, UCK2, NOL10, KIF18A, RAP2A, BOD1, GDI2, ZIC2, GTF3C6, SLC1A5, ERI3 and SAC3D1 may affect the prognosis of LIHC.
Pharmacist‐Led Intervention on the Inappropriate Use of Stress Ulcer Prophylaxis Pharmacotherapy in Intensive Care Units: A Systematic review
Authors: Xu Peipei , Yi Qiusha , Wang Cuitong , Zeng Linan , Olsen Keith M. , Zhao Rongsheng , Jiang Mingyan , Xu Ting , Zhang Lingli 
Published: October 2021

Background: Pharmacist’s direct intervention or participation in multidisciplinary management teams can improve the clinical outcome and quality of life of patients. We aimed to determine the effectiveness of pharmacist-led interventions on the inappropriate use of stress ulcer prophylaxis (SUP) pharmacotherapy in intensive care units (ICUs).Methods: A systematic review was performed for relevant studies using searched PubMed, EMBASE (Ovid), the Cochrane Library, Cochrane Central Register of Controlled Trials (CENTRAL), and four Chinese databases from the establishment of databases to 12 March 2020. We conducted a descriptive analysis of participants, the intervention content and delivery, and the effects on inappropriate medication rates.Results: From 529 records, 8 studies from 9 articles were included in the systematic review. The time of appropriateness judgment and the criteria of “appropriate” varied from included studies. Pharmacist interventions mainly included clarifying indications for SUP pharmacotherapy, education and awareness campaign, reviewed patients on SUP pharmacotherapy during rounds, and adjustments of drug use. Five (62.5%) studies found a significant intervention effect during hospitalization, while 2 (25%) studies at ICU transfer and 2 (25%) studies at hospital discharge. 4 (50%) studies identified the complications related to SUP pharmacotherapy and found no significant difference. 4 (50%) studies declared the pharmacist-led interventions were associated with cost savings.Conclusion: Pharmacist-led intervention is associated with a decrease in inappropriate use of SUP pharmacotherapy during hospitalization, at ICU transferred and hospital discharged, and a lot of medical cost savings. Further research is needed to determine whether pharmacist-led intervention is cost-effective.
Enhancement of the ion flux to the substrate through high-voltage biasing in an electron cyclotron resonance plasma and its application to high-speed deposition of conductive carbon film
Authors: Bae Hansin , Hamaguchi Ikumi , Sasai Kensuke , Suzuki Haruka , Toyoda Hirotaka 
Published: October 2021

Abstract
A method for enhancing ion flux to the substrate via high-voltage pulse biasing is investigated in an electron cyclotron resonance plasma. When high-voltage pulse biases above 500 V are applied to the stage, an increase in the stage current is observed, especially in the case of diverging magnetic field configurations in front of the bias stage. The growth and decay time constants of the plasma density and emission intensity are evaluated using a time-resolved Langmuir probe and emission spectroscopy while the pulse is on, and the enhancement of the ionization rate during the bias application is estimated using the zero-dimensional global model. The estimated density enhancement from the model is in good agreement with the measured one. From the numerical simulation of secondary electron trajectory, it is concluded that the electron confinement from the magnetic field is the key factor in plasma density enhancement during stage biasing. Using the high-density plasma produced by the bias voltage, conductive carbon is deposited at a high deposition rate of ∼4 nm s−1.
The project "The Civilizational heritage of Russia in Moscow" as a means of improving the cultural and historical literacy of schoolchildren
Authors: Юренко Ю.Ю. 
Published: October 2021

в статье рассматривается проведение культурно-просветительского проекта «Цивилизационное наследие России в Москве» в 2020 г., описывается методика реализации проекта, дается краткая оценка реакции учащихся и педагогов, делаются выводы о возможной трансляции полученного опыта для дальнейшей работы по культурной адаптации детей из семей мигрантов в школах Москвы и регионов России.
the article discusses the implementation of the cultural and educational project "The Civilizational Heritage of Russia in Moscow" in 2020, describes the methodology for the implementation of the project, gives a brief assessment of the reaction of schoolchildren and teachers, draws conclusions about the possible transmission of the experience gained for further work on the cultural adaptation of children from migrant families in schools of Moscow and regions of Russia.
Cooperative technologies as a condition for the formation of professionally significant qualities of the future teacher of primary education
Authors: Полтавская Н.Е. 
Published: October 2021

автор рассматривает кооперативные технологии как условие формирования профессионально значимых качеств будущего педагога начального образования в высшей школе. Проведенный теоретический анализ формирования профессионально значимых качеств педагога начального образования показал, что основными из них являются: высокая гражданско-патриотическая ответственность, социальная активность, педагогическое целеполагание и проектирование, креативность, рефлексия, самообладание. Применение кооперативных технологий позволяет решить профессионально-образовательные задачи, способствует формированию вышеуказанных качеств, развитию навыков вербализации и визуализации, умению слушать, разрешать возникающие проблемы, регулировать межличностные конфликты, преодолевать свои комплексы и барьеры.
author considers cooperative technologies as a condition for the formation of professionally significant qualities of the future teacher of primary education in higher education. Our theoretical analysis of the problem of forming professionally significant qualities of a primary education teacher has shown that the main ones are high civic and patriotic responsibility, social activity, pedagogical goal-setting and design creativity, reflection, self-control. The use of cooperative technologies allows you to solve professional and educational tasks, contributes to the formation of the above qualities, the development of verbalization and visualization skills, the ability to listen, solve emerging problems, regulate interpersonal conflicts, overcome your complexes and barriers.
Information and educational technologies as a resource for the development of an Islamic educational organization
Authors: Яковлева А.В. 
Published: October 2021

статья посвящена проблеме использования современных информационно-образовательных технологий в исламской образовательной организации. В условиях конфессионально обусловленной учебно-воспитательной среды цифровизация образовательного пространства вызывает ряд вопросов и опасений, касающихся сохранения качества образовательных результатов. Рассмотрены теоретические основы внедрения информационных технологий в процесс обучения и практика их применения в исламском институте.
the article is devoted to the problem of using modern information and educational technologies in an Islamic educational organization. In the context of a confessionally conditioned educational environment, the digitalization of the educational space raises a number of questions and concerns regarding the preservation of the quality of educational results. The theoretical foundations of the introduction of information technologies in the learning process and the practice of their application in the Islamic institute are considered.
Historical-Philosophical Research as a Fractal Universe Breaking
Authors: Морозов М.Ю. 
Published: October 2021

в статье исследуется объективная роль и значение историко-философского исследования в условиях тотального господства фрагментарности, что характерно для функционирования позднего этапа общества развитого товарного производства. Показывается, что теоретически развитое понятие фрактальности является адекватным выражением как гносеологической позиции фрагментарного индивида, воспроизводящегося в таком обществе, так и основных межсубъектных определений исторического движения на указанном этапе. Вопреки господствующему наглядно-образному представлению о фрактале обосновывается всеобщий характер и значимость этого понятия как логической категории, противоположной и диалектически сопряженной с категорией «тотальность», занимающей особое место в диалектической логике. Доказывается, что историко-философское исследование является основанием для снятия фрактальной одномерности в ее же собственной разрывно-фрагментарной логике.
the article explores the objective role and significance of historical-philosophical research in the conditions of total domination of fragmentation, which is the characteristic of late-stage functioning of the society of developed commodity production. It is shown that theoretically developed concept of fractality is an adequate expression of both the epistemological position of fragmented individual reproduced in such society and the main intersubjective definitions of historical movement at this stage. Contrary to the prevailing visual-image representation of the fractal, the universal nature and significance of this concept as a logical category is stated, which is opposite and dialectically connected to the category "totality", which occupies a special place in dialectical logic. It is proved that historical-philosophical research is the basis for the removal of the fractal one-dimensionality in its own discontinuous-fragmentary logic.