bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparing the Effects of Mastery Learning and Lectures on Nurses’ Oxygen Therapy Knowledge and Practice: A Quasi-Experimental Study in Southern Iran
Authors: Ahmadidarrehsima Sudabeh , Rafati Shideh , Jabalbarezi Mahnaz , Rafati Foozieh 
Published: September 2021

Abstract
Background and Aim: Improper administration of oxygen as an expensive drug has dangerous side effects. Nurses are responsible for performing this therapy and even prescribing it in emergencies. This study aimed to determine the effect of two methods of mastery learning and lectures on the oxygen therapy knowledge and practice of nurses in a teaching hospital in southern Iran.Materials and Methods: This quasi-experimental study was conducted on 50 nurses working in a teaching hospital in southern Iran. The participants were selected using convenience sampling and randomly divided into intervention and control groups. The members of the intervention group attended 4 oxygen therapy master learning sessions, while the members of the control group were trained using the lecture method for 4 sessions. The instruments used for data collection were a demographic information questionnaire and the researcher-made nurses’ oxygen therapy knowledge and practice inventories that were completed by the participants in both groups. The data were collected before the intervention and one week and three months after the intervention and analyzed using SPSS software with descriptive and inferential statistics.Results: The findings indicated that the nurses had poor oxygen therapy knowledge and practice before the intervention. Furthermore, there was no significant difference between the two groups in terms of the mean scores of oxygen therapy knowledge and practice before the intervention. It was also shown that oxygen therapy knowledge and practice were significantly improved one week and three months after the learning mastery intervention in the participants in the intervention group (P < 0.001). In contrast, only the oxygen therapy knowledge of the members of the control group showed a significant increase three months after the intervention compared to the pre-intervention stage (P = 0.04). Conclusion: The results of the present study showed that the mastery learning model is an effective model for improving and maintaining the nurses’ oxygen therapy knowledge and practice. Since nurses’ optimal practice improves the quality of care and increases patient safety, mastery learning can be used as an effective training technique to improve nurses’ oxygen therapy practice.
Induction Therapy and Outcome of Proliferative Lupus Nephritis in the Top End of Northern Australia – A single centre study retrospective study
Authors: Xu Chi , Goh Kim Ling , Abeyaratne Asanga , Priyadarshana Kelum 
Published: September 2021

Abstract
BackgroundLupus nephritis is a common manifestation of Systemic Lupus Erythematosus. Mycophenolate is recommended by guidelines for induction therapy in patients with proliferative lupus nephritis and nephrotic range proteinuria Class V lupus nephritis. Indigenous Australians suffer disproportionally from systemic lupus erythematosus compared to non-Indigenous Australians. MethodsWe retrospectively identified patients with newly diagnosed biopsy-proven class III lupus nephritis, class IV lupus nephritis and class V lupus nephritis with nephrotic range proteinuria from 1st Jan 2010 to 31st Dec 2019 in our institution and examined for the patterns of prescribed induction therapy and clinical outcome. The primary efficacy outcome of interest was the incidence of complete response (CR) and partial response (PR) at one-year post diagnosis as defined by the Kidney Disease: Improving Global Outcome (KDIGO) guideline. Secondary efficacy outcome was a composite of renal adverse outcome in the follow-up period. Adverse effect outcome of interest was any hospitalisations secondary to infections in the follow-up period. Continuous variables were compared using Student’s t-test or Mann-Whitney U-test. Categorical variables were summarised using frequencies and percentages and assessed by Fisher’s exact test. Time-to-event data was compared using the Kaplan-Meier method and Log-rank test. Count data were assessed using the Poisson’s regression method and expressed as incident rate ratio.Results20 of the 23 patients included in the analysis were managed with mycophenolate induction upfront. Indigenous Australian patients (N=15), compared to non-Indigenous patients (N=5) received lower cumulative dose of mycophenolate mofetil over the 24 weeks (375g vs. 256g, p<0.05), had a non-significant lower incidence of complete remission at 12 months (60% vs. 40%, p=0.617), higher incidence of composite renal outcome (0/5 patients vs. 5/15 patients, p=0.20) and higher incidence of infection related hospitalisations, (incident rate ratio 3.66, 95% confidence interval 0.89-15.09, p=0.073). ConclusionMycophenolate as upfront induction in Indigenous Australian patients were associated with lower incidence of remission and higher incidence of adverse outcomes. These observations bring the safety and efficacy profile of mycophenolate in Indigenous Australians into question.
Real-space imaging of phase transitions in bridged artificial kagome spin ice
Authors: Hofhuis Kevin , Skjærvø Sandra , Parchenko Sergii , Arava Hanu , Luo Zhaochu , Kleibert Armin , Derlet Peter , Heyderman Laura 
Published: September 2021

Abstract
In frustrated spin systems, magnetic phase transitions underpin the formation of exotic, frustration-driven magnetic phases. Of great importance is the ability to manipulate these transitions to access specific phases, which in turn provides a means to discover and control novel phenomena. Artificial spin systems, incorporating lithographically-fabricated arrays of dipolar-coupled nanomagnets that allow real-space observation of the magnetic configurations, provide such an opportunity. In particular, the kagome spin ice is predicted to have two phase transitions, one of which is to a low temperature phase whose long-range ground state order has not been observed experimentally. To achieve this order, we change the global symmetry of the artificial kagome system, by selectively tuning the near-field nanomagnet interactions through nanoscale bridges at the vertices. By precisely tuning the interactions, we can quantify the influence of frustration on such a transition, and find that the driving force for spin and charge ordering depends on the degeneracy strength at the vertex. For the first time, we are able to observe the evolution of the magnetic configurations associated with a phase transition in real space and time.
Development and Psychometric Evaluation of an Instrument for Preventing Occupational Neck Pain Behaviors in Teachers
Authors: Moradi Zohre , Tavafian Sedigheh Sadat , Kazemi Seyedeh Somayeh 
Published: September 2021

Abstract
Background: Development and psychometrics of a questionnaire for preventive occupational pain behaviors in teachers.Quantitative and qualitative research plan in tool development and validation.Method: A qualitative study was conducted in December 2020 with 25 participants to obtain the initial information of the questionnaire. Then content validity and face validity were performed. In the next stage, a questionnaire was distributed among the sample of teachers. In total, 146 teachers participated in this study (with a mean age 36.7; SD 8.92 years). Exploratory factor analysis was used to obtain the factor structure of the questionnaire. The correlation matrix in the case scale has been used to evaluate the validity of the structure. Internal stability (Cronbach's alpha) was calculated to assess reliability and internal correlation coefficient to assess stability.Results: Based on analysis of the exploratory factor, 8 factors with 43 substances, that together accounted for 65,25% variances were obtained. Also, the correlation matrix in the case scale to establish the validity of the questionnaire showed satisfactory results. The results of face validity showed that 4 factors were not approved and were removed from the questionnaire. Reliability evaluation with internal consistency method (Cronbach's alpha) showed excellent compatibility (0.87). The Intraclass correlation reliability assessment showed that the questionnaire has satisfactory stability (ICC) (0.92).Conclusion: This study provides the reliability and validity of the Occupational Pain Neck Preventive Behaviors Questionnaire. This study provides an instrument for evaluating occupational neck pain prevention behaviors among teachers. The instrument is useful for teachers and staff of administrative units and healthcare settings to implement appropriate interventions.
Risk Factors and Severity of Keratoconus on the East Coast of China
Authors: Mou Yujie , Qin Qiyu , Huang Xiaodan , Jin Xiuming 
Published: September 2021

Abstract
Purpose: This study aims to investigate the characteristics, potential risk factors and associated severity of keratoconus on the east coast of China. Methods: In this prospective case-control study, patients diagnosed with keratoconus were invited to fill in the online electronic questionnaire designed with the help of the App named WenJuanXing. Several questions like, sex, age of diagnosis and eye care habits were administered to each subject through this e-questionnaire. Corneal topographies at diagnosis taken from Pentacam were also collected. Results: 391 Chinese keratoconus outpatients were enrolled in this study, among which 159 patients were newly diagnosed. Only 3 patients (0.77%) had a positive family history of keratoconus. Atopy could be identified in 66.0% of our patients. A total of 357 patients (91.3%) mentioned the habit of eye rubbing, with 191 patients (48.8%) rubbing their eyes frequently. Patients with younger age at onset (P=0.005), male sex (P=0.042), frequent eye rubbing (P=0.003) and smoke (P=0.002) were found significantly associated with increased risk of acute hydrops. In newly diagnosed patients, 79.9% had the maximum keratometry (Kmax) more than 52D, with males and patients aged 21-30 being even more serious (P=0.009; P=0.005). Besides, in patients aged over 21, frequent eye rubbing was significantly associated with steeper Kmax and more severe astigmatism (all P＜0.05). Conclusion: Our results suggest that frequent eye rubbing is closely related to the severity of keratoconus in Chinese patients. Chinese keratoconus patients always had much serious disease condition at the time of diagnosis. Thus, increasing the publicity of keratoconus and advocating appropriate eye care habits are needed urgently in China.
SimulaD: A Novel Feature Selection Heuristics For Discrete Data
Authors: Besharati Mohammad Reza , Izadi Mohammad 
Published: September 2021

Abstract
For discrete big data which have a limited range of values, Conventional machine learning methods cannot be applied because we see clutter and overlapping of classes in such data: many data points from different classes overlap. In this paper we introduce a solution for this problem through a novel heuristics method. By applying a running average (with a window-size= d) we could transform Discrete data to broad-range, Continuous values. When we have more than 2 columns and one of them is containing data about the tags of classification (Class Column), we could compare and sort the features (Non-class Columns) based on the R2 coefficient of the regression for running averages. The parameters tuning could help us to select the best features (the non-class columns which have the best correlation with the Class Column). “Window size” and “Ordering” could be tuned to achieve the goal. This optimization problem is hard and we need an Algorithm (or Heuristics) for simplifying this tuning. We demonstrate a novel heuristics, Called Simulated Distillation (SimulaD), which could help us to gain a somehow good results with this optimization problem.
Effectiveness of Interventions to Improve Medication Adherence in Adults With Depressive Disorders: A Meta-Analysis
Authors: de León Beatriz González , Pino-Sedeño Tasmania del , Serrano-Pérez Pedro , Rodríguez-Álvarez Cristobalina , Bejarano-Quisoboni Daniel , Trujillo-Martín María M. 
Published: September 2021

Abstract
Background: Non-adherence to medications is a major obstacle in the treatment of depressive disorders. We systematically reviewed the literature to evaluate the effectiveness of interventions aimed at improving adherence to medications among adults with depressive disorders.Methods: We searched Medline, EMBASE, The Cochrane Central Register of Controlled Trials (CENTRAL), PsycINFO, Social Science Citation Index and Science Citation Index for randomized or non-randomized controlled trials up to September 2019. Risk of bias was assessed using the criteria of the Cochrane Collaboration. Meta-analyses, cumulative and meta-regression analyses for adherence were conducted.Results: Forty-five trials (n= 24,413) were included. Pooled estimate indicates an increase in the probability of adherence to antidepressants at 6 months with the different types of interventions (OR 1.28; 95% CI: 1.07 to 1.54). The improvement in adherence is obtained from 3 months (OR 1.57, 95% CI: 1.22 to 2.01) but it is attenuated at 12 months (OR 1.25, 95% CI: 0.99 to 1.53). Selected articles show methodological differences, mainly the diversity of both the severity of the depressive disorder and intervention procedures. Patients with depression and anxiety seem to benefit most from intervention (OR 2.77, 95% CI: 1.74 to 4.42) and collaborative care is the most effective intervention to improve adherence (OR 1.67, 95% CI: 1.17 to 2.40).Conclusions: Our findings indicate that interventions aimed at improving short and medium-term adherence to medications among adults with depressive disorders are effective. However, the evidence on the effectiveness of long-term adherence is insufficient and supports the need for further research efforts.International Prospective Register for Systematic Reviews (PROSPERO) number: CRD42017065723
Impact of COVID-19 on Malaysian Dental Students’ Physical, Mental, Financial and Academic Concerns
Authors: Lestari Widya , Yazid Nur Hazirah , Azhar Zawin Najah , Ismail Azlini , Sukotjo Cortino 
Published: September 2021

Abstract
Background
The coronavirus disease 2019 (COVID-19) caused by a novel coronavirus (SARS-CoV-2) has spread across the world at unprecedented speed and gained worldwide attention. The pandemic proved to hold an impact to humankind including dental students in all aspects of life. Dental students’ performances may indirectly be affected following the preventive measures in containing the disease. This study aims to evaluate the impact of COVID-19 pandemic on physical, mental, financial health and academic concern among dental students in Malaysia.
Methods
The current research implemented a cross sectional study among dental students in Malaysia. Assessment of the impact of COVID-19 on dental education was done by the distribution of a set of online survey consisting of 28 questions to dental students (n = 353) from public and private universities in Malaysia. The questionnaires include sociodemographic backgrounds and assessment on the 4 main domains.
Results
A total number of 353 respondents was recorded and 76.2% comprised of female. 59.7% were clinical students and 40.3% were preclinical students. 55.8% of the respondents attended hybrid mode of study. 78.0%, 76.5% and 91.8% students were concerned about their own emotional, physical health and the amount of clinical skill they acquire respectively. Year 3 students were found to be more concerned about their mental and financial health concern (p < 0.05).
Conclusions
COVID-19 pandemic had indeed significantly affected Malaysian dental students mainly due to fear of the quality of online learning and the amount of clinical skills acquired.
Overexpressing PLOD Family Genes Predict Poor Prognosis In Pancreatic Cancer
Authors: Zhang Jing , Tian Yan Zhang , Mo Shao Jian , Fu Xi Feng 
Published: September 2021

Abstract
Background: Pancreatic cancer is a common malignant tumor of digestive system. It has the characteristics of low early detection rate, large surgical trauma and high mortality. Multiple studies have shown that the PLOD family genes are closely associated with tumor progression and metastasis in many human cancers. However, The prognosis and biological function of PLOD family genes in PAAD have not been deeply discussed.Methods: GEPIA,GEO,HPA,CCLE,Kaplan-Meier Plotter,cBioPortal, LinkedOmics, DAVID6.8, STRING and TIMER were used to determine the prognostic values and biological function of PLOD family members in pancreatic cancer.Results: The mRNA and protein expression patterns of PLOD family members were noticeably upregulated in PAAD compared to normal tissue. In addition, PLOD family gene expression is also upregulated in pancreatic cancer cell lines.PLOD1 was significantly correlated with histological grade and pathological grade of pancreatic cancer. PLOD2 is related to histological grade.The high expression of PLOD1-2 was significantly correlated with the poor overall survival rate and relapse-free survival rate in patients with PAAD. In addition, PLODs has high sensitivity and specificity in distinguishing pancreatic cancer from normal tissues.Through the functional enrichment analysis of PLODs-related genes in pancreatic cancer, we found that PLODs was enriched in collagen fiber tissue structure, lysine degradation and collagen biosynthesis.Pathway analysis was confirmed PLODs regulates the proliferation, migration, and metastasis of pancreatic cancer through the RalGEF-Ral signaling pathway.The expression levels of PLOD1–2 were positively correlated with the activities of tumor-infiltrating immune cells, including CD8+T cells, neutrophils, macrophages and dendritic cells.The expression level of PLOD3 was inversely correlated with the infiltration level of CD8+T cells.The expression levels of PLOD1 were higher in pancreatic cancers with TP53 mutations as compared to pancreatic cancers without mutations.PLOD2 expression levels were increased in KRAS mutant pancreatic cancer.However, the expression level of PLOD3 is elevated in SMAD4 wild-type pancreatic cancer.Conclusion: The findings of this study could propose that individual PLOD genes or PLOD family genes as a whole could be potential prognostic biomarkers for PAAD.
Challenges In Reanalysis Products To Assess Extreme Weather Impacts On Yield Underestimate Drought
Authors: Grusson Youen , Barron Jennie 
Published: September 2021

Abstract
The incidence of dry or wet day sequences has a great influence on crops management and development. The lack of spatialized observed data with appropriate temporal resolution to investigate the changes that has occurred during the last century regarding the length and frequencies of those sequences has led to reliance on reanalysis products. However, the question can be raised about the suitability of those products when evaluating such climate indices and their impacts on crop production. Different products are here investigated to evaluate the way that succession of dry and wet days are depicted. We showed clearly that the frequency and intensity of dry and wet spells returned can differ widely between products. For instance, number of dry spell events can range from 1 to 11 over the same decade for two different products. This divergence in representation of spells could generate substantial differences in impact analysis of crop yields in agricultural modeling.
The Methods and Use of Questionnaires for the Diagnosis of Dental Phobia by Japanese Dental Practitioners Specializing in Special Needs Dentistry and Dental Anesthesiology: A Cross-Sectional Study
Authors: Ogawa Mika , Ayuse Terumi , Fujisawa Toshiaki , Sato Shuntaro , Ayuse Takao 
Published: September 2021

Abstract
Background
Dental phobia is covered by medical insurance; however, the diagnostic methods are not standardized in Japan. Therefore, the aim of this study was to investigate the methods and use of questionnaires for the diagnosis of dental phobia by Japanese dental practitioners specializing in special needs dentistry and dental anesthesiology.
Methods
We conducted an online survey to obtain information from the members of the Japanese Society for Disability and Oral Health (JSDH, n = 5134) and the Japanese Dental Society of Anesthesiology (JDSA, n = 2759). Response items included gender, qualification, affiliation type, methods of diagnosis and management of dental phobia, use of questionnaire, need for new evaluation methods for the diagnosis of dental phobia, and others. The chi-squared test was used to compare answers between the three groups (JSDH only, JDSA only, and both). Multiple logistic regression analysis was conducted to identify factors associated with the use of an assessment questionnaire.
Results
Data were obtained from 614 practitioners (only JSDH: n = 329, only JDSA: n = 195, both JSDH and JDSA: n = 90, response rate: 7.8% [614/7,893], men: n = 364 [58.5%]). Only 9.7% practitioners used questionnaires to quantify the level of dental anxiety. The members of both JSDH and JDSA used questionnaires more frequently than members only of the JSDH (19% and 7.1%, respectively; Bonferroni corrected p < 0.01). Most practitioners (89.1%) diagnosed dental phobia based on patient complaints of fear of treatment. Further, majority of the participants (73.3%) felt the need for a new diagnostic method for “dental phobia”. Multiple logistic regression analysis showed that membership of the JSDH only was negatively related (odds ratio [OR] = 0.32, 95% confidence interval [CI] : 0.15—0.68), and use of behavioral therapy was positively related (OR = 2.51, 95% CI : 1.27—5.20) to the use of a questionnaire.
Conclusions
The results of this study showed that the use of questionnaires was very low, patients’ subjective opinions were commonly used to diagnose dental phobia, and a new diagnostic criterion was needed among practitioners. Therefore, it is important to establish standardized methods for diagnosing dental phobia in Japan.
Transition Sandwich Janus Membrane of Cellulose Acetate and Polyurethane Nanofibers For Oil-Water Separation
Authors: Zhang Yong , Yang Mei , Zhou Yuan , Yao Anrong , Han Yanting , Shi Yidong , Cheng Fei , Zhou Mi , Zhu Puxin , Tan Lin 
Published: September 2021

Abstract
Through sequential electrospinning, a sandwich Janus membrane (PU-(CA/PU)-CA) was constructed with hydrophobic polyurethane (PU) nanofiber membrane as the top layer, cellulose acetate/polyurethane (CA/PU) blend nanofiber membrane as the intermediate transition layer and hydrophilic cellulose acetate (CA) nanofiber membrane as the bottom layer. The effects of membrane structure, composition and thickness on the mechanical properties, permeability and separation ability of PU-(CA/PU)-CA nanofiber membrane were studied. The results show that the transition sandwich structure PU-(CA/PU)-CA membrane has good mechanical properties, high permeability and selective separation ability, and can realize the unidirectional transmission of water and efficient oil-water separation. When the membrane thickness is 80 μm, the hydraulic permeability is 3.4×104 L/(m2 h bar), the oil-water separation efficiency reaches 99%, and the tensile strength is 95.8% higher than that of the double-layer PU-CA membrane without intermediate transition layer. The thermal stability and antifouling ability of PU-(CA/PU)-CA nanofiber membrane have also been improved, and the reusability is good. CA/PU transition interlayer improves the interfacial compatibility between CA and PU nanofiber membrane, enhances the performance of PU-(CA/PU)-CA nanofiber Janus membrane, and shows its application prospect in the field of separation and purification.