bluuebunny/crossref_metadata_2025_split huggingface dataset:
Corporate Social Responsibility Research in the Journal of Management Studies: A Shift from a Business‐Centric to a Society‐Centric Focus
Authors: Wickert Christopher 
Published: September 2021

AbstractThis introduction to the Thematic Collection on Corporate Social Responsibility (CSR) tracks the evolution of CSR research published in the Journal of Management Studies from 2006 until 2021. Alongside the mainstreaming of CSR within management studies, CSR research in JMS has progressed from a business‐centric to a society‐centric focus. The business‐centric focus centres on the financial implications of CSR on business firms, and advocates CSR to the extent that it leads to improved financial performance or some other competitive advantage for the firm. The society‐centric focus asks broader questions about the appropriate role and location of business in society and its political and institutional contexts, and it reflects a wider set of variables of interest beyond firm financial performance. Understanding this evolution is crucial because it helps to elucidate where CSR research is headed and how the role of business in society is conceptualised. Based on these developments, I outline three emergent avenues for future research: the reintegration of governments as important actors shaping CSR, the need to reorient the dependent variables used in CSR research toward tangible social and ecological outcomes, and the importance of CSR research tackling interrelated societal crises such as the COVID‐19 pandemic and the climate crisis.
A review of the antimicrobial activity of thermodynamically stable microemulsions
Authors: Al-Adham I.S.I. , Jaber N. , Al-Remawi M. , Al-Akayleh F. , Al-Kaissi E. , Ali Agha A.S.A. , Fitzsimmons L.B. , Collier P.J. 
Published: September 2021

Abstract
Microemulsions are thermodynamically stable, transparent, isotropic mixtures of oil, water and surfactant (and sometimes a co-surfactant), which have shown potential for widespread application in disinfection and self-preservation. This is thought to be due to an innate antimicrobial effect. It is suggested that the antimicrobial nature of microemulsions is the result of a combination of their inherent kinetic energy and their containing surfactants, which are known to aid the disruption of bacterial membranes. This review examines the contemporary evidence in support of this theory.
Autophagic vacuolar myopathy: Danon disease and related myopathies
Authors: Sugie Kazuma 
Published: September 2021

AbstractAutophagic vacuolar myopathy is a subgroup of muscle diseases defined as a condition in which autophagic vacuoles are present as a muscle pathological feature and is caused by abnormality of autophagy in skeletal muscles. There is an autophagic vacuolar myopathy characterized by the presence of specific autophagic vacuoles known as autophagic vacuoles with sarcolemmal features (AVSF). It is referred to as AVSF myopathy and includes Danon disease and related myopathies. Danon disease is an X‐linked dominant disease associated with a primary deficiency of lysosomal‐associated membrane protein 2 in which severe hypertrophic cardiomyopathy and myopathy develop. Cardiomyopathy is a determinant prognostic factor of this disease, and heart transplantation is still the sole radical treatment. The pathomechanism of AVSF myopathy is considered to be caused by abnormality of autophagy resulting from primary lysosomal dysfunction.
Medium‐Term Follow‐Up Outcomes of One‐Stage Posterior Lumbosacral or Lumbopelvic Fixation in the Management of Lumbosacral Junction Tuberculosis in Adults
Authors: Xu Zhenchao , Zhang Zhen , Wang Xiyang , Zhang Yilu , Wu Yunqi 
Published: September 2021

ObjectiveTo evaluate the medium‐term outcomes of one‐stage posterior lumbosacral or lumbopelvic fixation treatment of lumbosacral junction tuberculosis in adults.MethodsThis retrospective study enrolled a total of 38 adult patients (24 males and 14 females) with an average age of 48.0 ± 13.0 years (range, 25–75 years) during the period from February 2008 to July 2015. All patients were treated by one‐stage posterior debridement, interbody fusion, lumbosacral or lumbopelvic fixation, and postural drainage. After pedicle screw or iliac screw fixation, a hemi‐laminectomy or laminectomy was performed on the severely damaged side of the lesion segment. Intervertebral bone grafting and intertransverse bone grafting were performed after clearing the focus of tuberculosis. All cases were followed up for at least 5 years. Intraoperative blood loss, operative time, erythrocyte sedimentation rate (ESR), pain intensity was assessed by visual analog scale (VAS) score; neurological function was assessed by Japanese Orthopaedic Association (JOA) score; quality of life was assessed by Oswestry Disability Index (ODI); functional outcome, lumbosacral angle, and fusion time were gathered and analyzed. All data expressed as mean ± standard deviation.ResultsDuring the 66.2 ± 4.4 months (range, 60–78 months) follow‐up, all patients achieved clinical cure without severe complications. The intraoperative blood loss was 726.3 ± 151.9 mL (range, 400–1100 mL) and the operative time was 137.6 ± 22.5 min (range, 110–200 min). The ESR decreased to normal levels within (11.8 ± 2.6 mm/h) 3 months postoperatively. The VAS score significantly decreased from 6.8 ± 1.1 preoperatively to 0.8 ± 0.7 at the final follow‐up (P < 0.01). The mean JOA improved from preoperative 18.5 ± 2.9 to 26.9 ± 1.1 at the last visit (P < 0.01). The mean ODI was 44.3 ± 6.7 and significantly decreased to 9.3 ± 1.9 at the final observation (P < 0.01). Patient‐reported outcomes as measured by Kirkaldy‐Willis criteria were excellent in 21 cases, good in 16 cases, and fair in one case; there were no poor outcomes. Lumbosacral angle increased from the preoperative values of 21.7° ± 1.8° to the postoperative values of 26.4° ± 1.4° (P < 0.01), with an angle loss of 1.2° ± 0.7° at the last follow‐up. Bone fusion occurred on average 12.8 ± 1.9 months (range, 9–15 months) after surgery. No nonunion, pseudarthrosis, loosening or fracture of instruments occurred at the last follow‐up.ConclusionOne‐stage posterior debridement, interbody fusion, lumbosacral or lumbopelvic fixation, and postural drainage according to the severity of sacral destruction is an effective and highly safe procedure to treat lumbosacral junction tuberculosis in adults.
Endogenous indole‐3‐acetic acid and nitric oxide are required for calcium‐mediated alleviation of copper oxide nanoparticles toxicity in wheat seedlings
Authors: Yadav Vaishali , Gill Rafaqat Ali , Arif Namira , Gill Skhawat Ali , Singh Vijay Pratap , Ramawat Naleeni , Zhou Weijun , Tripathi Durgesh Kumar , Chauhan Devendra K. 
Published: September 2021

ABSTRACTThe action of nanoparticles is increasingly being studied in recent years to minimize their toxic impacts. Besides this, efforts are also being made to minimize their toxicity in crop plants by using various chemicals, i.e. nutrients, donors of signaling molecules, plant hormones, and so on. However, associated alleviatory mechanisms are still not well known. Therefore, in the present study, we have investigated the toxicity of CuONPs and its mitigation by exogenously applied calcium (Ca). The focus was on whether indole‐3‐acetic acid (IAA) or endogenous nitric oxide (NO) has any role in accomplishing this task. CuONPs declined wheat growth due to increased accumulation of Cu and oxidative stress markers such as superoxide radicals, hydrogen peroxide, and lipid peroxidation (malondialdehyde) and it was also accompanied by a decline in endogenous NO. CuONPs also altered the redox status of ascorbate and glutathione by inhibiting the activity of their regenerating enzymes. This collectively leads to cell death in wheat seedlings. However, exogenous supplementation of Ca mitigated toxic effects of CuONPs by reducing the excess accumulation of Cu, which caused remarkable enhancement in growth, protein contents, photosynthetic pigments, and endogenous NO; altogether protecting wheat roots from cell death. Interestingly, addition of 2,3,5‐triiodobenzoic acid (TIBA) further increased CuONPs toxicity even in the presence of Ca, but the addition of IAA rescued this effect of TIBA. These results clearly show that Ca mitigates CuONPs toxicity in wheat seedlings by involving IAA. Further, the results also showed that endogenous NO has a positive and indispensable role in Ca‐mediated mitigation of CuONPs toxicity in wheat seedlings.
The role of forskolin as a lipolytic stimulator during in vitro oocyte maturation and the in vitro embryo production of livestock
Authors: Raza Sayed Haidar Abbas , Abd El‐Aziz Ayman H. , Abdelnour Sameh A. , Easa Ahmed A. , Alagawany Mahmoud , Farag Mayada R. , Al‐Mutary Mohsen G. , Elfadadny Ahmed , Khan Rajwali , Quan Guobo , Cheng Gong , Zan Linsen 
Published: September 2021

AbstractCryopreservation is a modern technique which assists in the preservation of genetic material from oocytes and embryos for a long time. However, elevated vulnerability to cryopreservation due to the large accumulation of intracellular lipids within oocytes or embryos avoids success of this method. These lipids remain the main crucial factor limiting survival rates of oocytes and embryos after thawing. Lipid ingathering in the oocyte cytoplasm augments lipid peroxidation (LPO) and oxidative stress increases the apoptosis process, declines the viability after thawing, declines cytoskeleton actin filament injuries, lowers the blastocyst rates and reduces cryotolerance in the early stages of embryo development. There have been several attempts to reduce the ingathering of intracellular lipids in oocytes or embryos during the cryopreservation process, in that way enhancing the competence of cryopreserved oocytes or embryos and increasing their viability. One of the most applied agents for chemical delipidation is forskolin. Forskolin exhibited a possible part in improving the oocytes cryopreservation through stimulating cyclic adenosine monophosphate (cAMP) production. The main purpose of cAMP modulation is to provide energy to sustain the mammalian oocytes´ meiotic arrest. The purpose of the existing article is to assess and offer more evidence concerning the forskolin utilization as a modulator of cAMP during the cryopreservation of oocytes and its influence on meiosis completion and the reorganization of cytoplasm, which are prerequisites for the development of oocytes in addition to the contribution to fertilization and subsequently, the development of embryos.
Mapping the literature on child marriage: A critical engagement
Authors: O'Quinn Jamie 
Published: September 2021

AbstractU.S. “child marriage”—marriage including at least one person under the age of 18—is legal and practiced in 44 states. In this article, I map the existing literature on child marriage and offer insights on how child marriage can expand our sociological understandings of marriage, gender inequality, and youth sexualities. Social scientists have almost exclusively focused on child marriage in the Global South at the expense of understanding child marriage in the Global North, which I argue reinforces racist and xenophobic narratives that cast child marriage as a non‐Western social problem. The research on U.S. child marriage that does exist focuses on the consequences, rather than the causes, of child marriage, which may shift focus away from a structural understanding of how intersecting inequalities shape girls' likelihood of getting married as minors. I position a sociology of U.S. child marriage at the intersection of sociological understandings of marriage and gender inequality and critical research on youth sexualities. I conclude by calling for intersectional research on U.S. child marriage that builds on these literatures, examining how girls' sexualities are racialized, gendered, and classed within the institution of marriage.
Nitric oxide synthase inhibition in healthy adults reduces regional and total cerebral macrovascular blood flow and microvascular perfusion
Authors: Carter Katrina J. , Ward Aaron T. , Kellawan J. Mikhail , Eldridge Marlowe W. , Al‐Subu Awni , Walker Benjamin J. , Lee Jeffrey W. , Wieben Oliver , Schrage William G. 
Published: September 2021

AbstractThe importance of nitric oxide (NO) in regulating cerebral blood flow (CBF) remains unresolved, due in part to methodological approaches, which lack a comprehensive assessment of both global and regional effects. Importantly, NO synthase (NOS) expression and activity appear greater in some anterior brain regions, suggesting region‐specific NOS influence on CBF. We hypothesized that NO contributes to basal CBF in healthy adults, in a regionally distinct pattern that predominates in the anterior circulation. Fourteen healthy adults (7 females; 24 ± 5 years) underwent two magnetic resonance imaging (MRI) study visits with saline (placebo) or the NOS inhibitor, L‐NMMA, administered in a randomized, single‐blind approach. 4D flow MRI quantified total and regional macrovascular CBF, whereas arterial spin labelling (ASL) MRI quantified total and regional microvascular perfusion. L‐NMMA (or volume‐matched saline) was infused intravenously for 5 min prior to imaging. L‐NMMA reduced CBF (L‐NMMA: 722 ± 100vs. placebo: 771 ± 121 ml/min,P= 0.01) with similar relative reductions (5–7%) in anterior and posterior cerebral circulations, due in part to the reduced cross‐sectional area of 9 of 11 large cerebral arteries. Global microvascular perfusion (ASL) was reduced by L‐NMMA (L‐NMMA: 42 ± 7vs. placebo: 47 ± 8 ml/100g/min,P= 0.02), with 7–11% reductions in both hemispheres of the frontal, parietal and temporal lobes, and in the left occipital lobe. We conclude that NO contributes to macrovascular and microvascular regulation including larger artery resting diameter. Contrary to our hypothesis, the influence of NO on cerebral perfusion appears regionally uniform in healthy young adults.Key pointsCerebral blood flow (CBF) is vital for brain health, but the signals that are key to regulating CBF remain unclear.Nitric oxide (NO) is produced in the brain, but its importance in regulating CBF remains controversial since prior studies have not studied all regions of the brain simultaneously.Using modern MRI approaches, a drug that inhibits the enzymes that make NO (L‐NMMA) reduced CBF by up to 11% in different brain regions.NO helps maintain proper CBF in healthy adults. These data will help us understand whether the reductions in CBF that occur during ageing or cardiovascular disease are related to shifts in NO signalling.
Numerical and Orthogonal Study on Optimization Analysis of Structure Parameters of Bubble Breaker for Electrical Submersible Pump System
Authors: Xie Chuan , Liu Yonghui , Li Xiaoping , Wang Guangbiao , Wang Qinghua , Zeng Fanhua 
Published: September 2021

Abstract
Under slug flow conditions, electrical submersible pumps (ESPs) show a low efficiency due to Taylor bubbles, which cause pressure surging and gas pockets and the further deterioration of pressure boosting ability. In this study, a novel downhole bubble breaker is designed for mitigating the impact in ESP under slug flow conditions. The computational fluid dynamics-population balance model (CFD-PBM) coupled approach was used to calculate the bubble breaker's average bubble diameter to evaluate its efficiency. Meanwhile, experimental studies were conducted and compared with numerical results. Also, matlab and DIP-image technology was used to calculate the bubble diameter. Compared with experimental results, the simulation results agree well. Furthermore, the novel bubble breaker's performance was studied by orthogonal approach. The best result of range analysis is A2B3C4D1E4 (α = 30 deg, L = 300 mm, R = 2:1, vsg = 0.2 m/s, and vsl = 0.08 m/s), and sensitively analysis results present that the range of impact intensity are A (inlet angle) &gt; E (superficial gas velocity) &gt; B (total length) &gt; D (superficial liquid velocity) &gt; C (ratio of the gas–liquid channel). The optimal structure's bubble diameters are all less than that of the original structure, with a superficial gas velocity range of 0.2–0.6 m/s. The downstream bubble diameter of the optimal bubble is about 31.6% lower than the original structure at the maximum value point.
Combined Physical Activity and Sitting Time Association on Older Adults’ Body Mass Index: Cross-Sectional Findings From the Brazilian Longitudinal Study of Aging
Authors: Amorim Juleimar S.C. , Torres Juliana L. , Peixoto Sérgio V. 
Published: September 2021

This study examined isolated and combined associations of physical activity (PA) and sitting time (ST) with body mass index (BMI) among older Brazilian adults. We have analyzed baseline data of 8,177 participants aged 50 years and older from the Brazilian Longitudinal Study of Aging. Respondents were categorized into sufficient PA/low ST, sufficient PA/high ST, insufficient PA/low ST, or insufficient PA/high ST using the Short Version of International Physical Activity Questionnaire. Multinomial logistic regression analysis examined the associations of being underweight (BMI, <18 kg/m2), overweight (BMI, 25–29.9 kg/m2), and obese (BMI, ≥30 kg/m2) with PA and ST categories. High ST (≥165 min/day) was associated with overweight (odds ratio, 1.26; 95% confidence interval [1.11, 1.44]) and obesity (odds ratio, 1.43; 95% confidence interval [1.21, 1.70]). However, no association was observed between PA and BMI. Participants in the insufficient and sufficient PA/high ST categories were more likely to be obese after adjusting for sociodemographic and health condition. Our findings call for public health initiatives that consider reducing ST in older adults.
Improving transparent team communication with the ‘Glass Door’ decal communication tool: a mixed methods analysis of family and staff perspectives
Authors: Zavalkoff Samara , Mazaniello-Chezol Maud , O'Donnell Shauna , Cunningham Kadine , Almazyad Mohammed , O'Reilly Ashley , Macedo Kimberley , Lammeree Kimberly , Mitchell Ellen , Roussianos Chrysanthi , Antonacci Marie , Cunnigham Gabrielle , Park Matthew , Gottesman Ronald 
Published: September 2021

ObjectiveTo determine the value and perspectives of intensive care unit (ICU) healthcare professionals (HCPs) and families about the Glass Door (GD) decal team communication tool.DesignQuality improvement methodology was used to design, test and implement the GD. Uptake was measured through audit. Impact was assessed through mixed methodology (survey of ICU HCPs (n=96) and semi-structured interviews of HCPs (n=10) and families (n=7)).SettingEighteen bed, closed, mixed medical–surgical–cardiac ICU in a tertiary care, university-affiliated, paediatric hospital.PopulationInterdisciplinary ICU HCPs and families of children admitted to the ICU.InterventionA transparent template (the GD) applied to the outside of ICU patients’ doors with sections for HCPs names, physiological goals and planned tests and treatments for the day. Medical staff completed the GD in rounds (AM and PM) and any HCP caring for the patient updated it throughout the day.Measurements and main resultsAfter 3 months, 96% of 613 doors were employed of which 99% respected confidentiality. ICU HCPs reported improved understanding of the patient’s plan (84% today vs 59% pre-GD, p<0.001) and sense that families were up-to-date (79% today vs 46% pre-GD, p<0.001). Based on semi-structured interviews, the GD promoted a shared understanding of the plan contributing to care continuity. The GD reassured families the team is working together and fostered family engagement in the care. Routine family experience surveys showed no change in families’ sense of privacy during admission; families denied the GD’s anticipated compromise of confidentiality.ConclusionsThe GD decal communication tool, visible on the patient’s door, improved ICU HCPs’ perceived knowledge of their patient’s plan. The GD improved the shared mental model, facilitated teaching and information transfer and fostered family engagement. Challenges included knowing the rules for use and consistent application. Concerns initially raised by HCPs about confidentiality were denied by families.
Evaluating the effect of driving distance to the nearest higher level trauma centre on undertriage: a cohort study
Authors: Waalwijk Job F , Lokerman Robin D , van der Sluijs Rogier , Fiddelers Audrey A A , Leenen Luke P H , Poeze Martijn , van Heijl Mark 
Published: September 2021

BackgroundIt is of great importance that emergency medical services professionals transport trauma patients in need of specialised care to higher level trauma centres to achieve optimal patient outcomes. Possibly, undertriage is more likely to occur in patients with a longer distance to the nearest higher level trauma centre. This study aims to determine the association between driving distance and undertriage.MethodThis prospective cohort study was conducted from January 2015 to December 2017. All trauma patients in need of specialised care that were transported to a trauma centre by emergency medical services professionals from eight ambulance regions in the Netherlands were included. Patients with critical resource use or an Injury Severity Score ≥16 were defined as in need of specialised care. Driving distance was calculated between the scene of injury and the nearest higher level trauma centre. Undertriage was defined as transporting a patient in need of specialised care to a lower level trauma centre. Generalised linear models adjusting for confounders were constructed to determine the association between driving distance to the nearest higher level trauma centre per 1 and 10 km and undertriage. A sensitivity analysis was conducted with a generalised linear model including inverse probability weights.Results6101 patients, of which 4404 patients with critical resource use and 3760 patients with an Injury Severity Score ≥16, were included. The adjusted generalised linear model demonstrated a significant association between a 1 km (OR 1.04; 95% CI 1.04 to 1.05) and 10 kilometre (OR 1.50; 95% CI 1.42 to 1.58) increase in driving distance and undertriage in patients with critical resource use. Also in patients with an Injury Severity Score ≥16, a significant association between driving distance (1 km (OR 1.06; 95% CI 1.06 to 1.07), 10 km (OR 1.83; 95% CI 1.71 to 1.95)) and undertriage was observed.ConclusionPatients in need of specialised care are less likely to be transported to the appropriate trauma centre with increasing driving distance. Our results suggest that emergency medical services professionals incorporate driving distance into their decision making regarding transport destinations, although distance is not included in the triage protocol.