bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wordify: A Tool for Discovering and Differentiating Consumer Vocabularies
Authors: Hovy Dirk , Melumad Shiri , Inman J Jeffrey 
Published: March 2021

Abstract
This work describes and illustrates a free and easy-to-use online text-analysis tool for understanding how consumer word use varies across contexts. The tool, Wordify, uses randomized logistic regression (RLR) to identify the words that best discriminate texts drawn from different pre-classified corpora, such as posts written by men versus women, or texts containing mostly negative versus positive valence. We present illustrative examples to show how the tool can be used for such diverse purposes as (1) uncovering the distinctive vocabularies that consumers use when writing reviews on smartphones versus PCs, (2) discovering how the words used in Tweets differ between presumed supporters and opponents of a controversial ad, and (3) expanding the dictionaries of dictionary-based sentiment-measurement tools. We show empirically that Wordify’s RLR algorithm performs better at discriminating vocabularies than support vector machines and chi-square selectors, while offering significant advantages in computing time. A discussion is also provided on the use of Wordify in conjunction with other text-analysis tools, such as probabilistic topic modeling and sentiment analysis, to gain more profound knowledge of the role of language in consumer behavior.
Power and Privilege
Authors: Koenig Alexa , Egan Ulic 
Published: March 2021

Abstract
Digital open source information — including the videos and photographs that people post to social media and other publicly accessible platforms — is increasingly valued as a critical source of evidence. While investigators have repeatedly established the value of open source information for researching a range of crimes, there is a subset of crimes that investigators have struggled to address with digital open sources — namely, sexual violence. In this article, we report on findings pulled from our interviews with international investigators and gender experts with regards to the perceived strengths and weaknesses of integrating digital open source information into international criminal investigations of sexual violence. More specifically, we elaborate on three insights into how open source investigations may be refined to better respect and protect the interests of survivors: by considering contextual issues related to ethics, power, and privilege, including the identity of the investigator and of the victims; by integrating a gender analysis and an intersectional analysis into online investigation planning; and by being thoughtful about consent, privacy, trauma and control — including who determines what happens with open source information and how such information is used in courts. We conclude with a discussion of what is needed to strengthen the efficacy and ethics of sexual violence investigations through the use of digital open sources.
First Report of Chaetocnema minuta (Coleoptera: Chrysomelidae) Associated With Turfgrass Damage in the Desert Southwest United States
Authors: Van Dyke Adam , McGraw Benjamin A 
Published: March 2021

Abstract
Chaetocnema minuta Melsh., a Nearctic flea beetle, has been recently isolated from damaged perennial ryegrass (Lolium perenne L. var. Palmer/Prelude) and hybrid bermudagrass (Cynodon dactylon L. Pers. × Cynodon transvaalensis Burtt Davy var. Midiron) in southern Utah and Nevada, respectively. Though previous surveys have found this insect associated with grasses, this short communication is the first report of economic damage to turfgrasses. Little is known about C. minuta seasonal phenology and host plant damage, and the distribution and understanding of the population dynamics in the Southwestern United States remain unstudied. Area turfgrass managers report the need for multiple insecticide applications throughout the growing season to maintain populations below turf damaging levels. This report serves to characterize turfgrass damage and document monitoring efforts to assist with future management programs.
Dynamic landscapes in northwestern North America structured populations of wolverines (Gulo gulo)
Authors: Krejsa Dianna M , Talbot Sandra L , Sage George K , Sonsthagen Sarah A , Jung Thomas S , Magoun Audrey J , Cook Joseph A 
Published: March 2021

Abstract
Cyclic climatic and glacial fluctuations of the Late Quaternary produced a dynamic biogeographic history for high latitudes. To refine our understanding of this history in northwestern North America, we explored geographic structure in a wide-ranging carnivore, the wolverine (Gulo gulo). We examined genetic variation in populations across mainland Alaska, coastal Southeast Alaska, and mainland western Canada using nuclear microsatellite genotypes and sequence data from the mitochondrial DNA (mtDNA) control region and Cytochrome b (Cytb) gene. Data from maternally inherited mtDNA reflect stable populations in Northwest Alaska, suggesting the region harbored wolverine populations since at least the Last Glacial Maximum (LGM; 21 Kya), consistent with their persistence in the fossil record of Beringia. Populations in Southeast Alaska are characterized by minimal divergence, with no genetic signature of long-term refugial persistence (consistent with the lack of pre-Holocene fossil records there). The Kenai Peninsula population exhibits mixed signatures depending on marker type: mtDNA data indicate stability (i.e., historical persistence) and include a private haplotype, whereas biparentally inherited microsatellites exhibit relatively low variation and a lack of private alleles consistent with a more recent Holocene colonization of the peninsula. Our genetic work is largely consistent with the early 20th century taxonomic hypothesis that wolverines on the Kenai Peninsula belong to a distinct subspecies. Our finding of significant genetic differentiation of wolverines inhabiting the Kenai Peninsula, coupled with the peninsula’s burgeoning human population and the wolverine’s known sensitivity to anthropogenic impacts, provides valuable foundational data that can be used to inform conservation and management prescriptions for wolverines inhabiting these landscapes.
Problems and Issues Concerning Social Integration of Elderly Refugees in Turkey
Authors: Özmete Emine , Pak Melike , Duru Serdarhan 
Published: March 2021

Abstract
Elderly refugees reflect a vulnerable group within the refugee communities. When the difficulties of the old age and the migration process come together, difficulties and problems tend to increase. Considering the rise in the elderly and refugee population, the social integration of elderly refugees were discussed in this study. Elderly refugees had health problems, language problems, isolation and formal problems mostly. Women refugees seemed to be more disadvantaged in terms of education, language, income and employment. Language, poverty and being in a different country were the factors that made the social integration of elderly refugees difficult, while facilitating factors were evaluated as common religion, host country characteristics and social networks. Specific services and gerontological social work practices should be created that eliminate the challenging factors and emphasize the facilitating factors of the social integration for elderly refugees.
A Pilot Study of a Stress Management Program for Incarcerated Veterans
Authors: Sylvia Louisa G , Chudnofsky Rana , Fredriksson Stacie , Xu Bingyu , McCarthy Megan D , Francona Jacque , Hart Betsy R , Millstein Rachel , Mehta Darshan H , Park Elyse R , Fricchione Gregory L 
Published: March 2021

ABSTRACT

Introduction
Veterans involved in the justice system are an understudied population warranting attention given their higher risk of mental health concerns and psychosocial challenges. Thus, there is a need for programs to support the psychological health of incarcerated veterans. The present study sought to determine the acceptability and effectiveness of a mind-body stress reduction program for incarcerated veterans.

Materials and Methods
Twenty-four incarcerated veterans (100% male; Mage = 44.87 (SD = 13.84)) completed a 6 week mind-body stress reduction course, or Resilient Warrior. Participants completed validated, self-report assessments of mood, functioning, mindfulness, and coping at pre- and post-program as well as having post-program qualitative feedback surveys.

Results
Results showed improvement in depressive symptom severity, self-efficacy, and resilience over the study duration (P &lt; .05), but not stress reactivity, mindfulness, sleep disturbance, or perceived stress. The intervention was reported as helpful by 96% of participants, with 86% of participants stating they would recommend the course to others.

Conclusions
The Resilient Warrior program is acceptable and well-tolerated for incarcerated veterans as well as may improve aspects of psychological health. Future studies could examine how stress reductions program might improve recidivism rates and quality of life after the release of incarcerated veterans.
Limited proteolysis by acrosin affects sperm-binding and mechanical resilience of the mouse zona pellucida
Authors: Kuske Michael , Floehr Julia , Yiallouros Irene , Michna Thomas , Jahnen-Dechent Willi , Tenzer Stefan , Stöcker Walter , Körschgen Hagen 
Published: March 2021

Abstract
The encounter of oocyte and sperm is the key event initiating embryonic development in mammals. Crucial functions of this existential interaction are determined by proteolytic enzymes, such as acrosin, carried in the sperm head acrosome, and ovastacin, stored in the oocyte cortical granules. Ovastacin is released upon fertilisation to cleave the zona pellucida, a glycoprotein matrix surrounding the oocyte. This limited proteolysis hardens the oocyte envelope, and thereby provides a definitive block against polyspermy and protects the developing embryo. On the other hand, acrosin, the renowned and most abundant acrosomal protease, has been thought to enable sperm to penetrate the oocyte envelope. Depending on the species, proteolytic cleavage of the zona pellucida by acrosin is either essential or conducive for fertilisation. However, the specific target cleavage sites and the resulting physiological consequences of this proteolysis remained obscure. Here, we treated native mouse zonae pellucidae with active acrosin and identified two cleavage sites in zona pellucida protein 1 (ZP1), five in ZP2 and one in ZP3 by mass spectrometry. Several of these sites are highly conserved in mammals. Remarkably, limited proteolysis by acrosin leads to zona pellucida remodelling rather than degradation. Thus, acrosin affects both sperm binding and mechanical resilience of the zona pellucida, as assessed by microscopy and nanoindentation measurements, respectively. Furthermore, we ascertained potential regulatory effects of acrosin, via activation of latent pro-ovastacin and inactivation of fetuin-B, a tight binding inhibitor of ovastacin. These results offer novel insights into the complex proteolytic network modifying the extracellular matrix of the mouse oocyte, which might apply also to other species.
Exploring human porphobilinogen synthase metalloprotein by quantum biochemistry and evolutionary methods
Authors: Barbosa E D , Neto J X Lima , Teixeira D G , Bezerra K S , do Amaral V S , Oliveira J I N , Lima J P M Santos , Machado L D , Fulco U L 
Published: March 2021

Abstract
Previous studies have shown the porphobilinogen synthase (PBGS) zinc-binding mechanism and its conservation among the living cells. However, the precise molecular interaction of zinc with the active center of the enzyme is unknown. In particular, quantum chemistry techniques within the density functional theory (DFT) framework have been the key methodology to describe metalloproteins, when one is looking for a compromise between accuracy and computational feasibility. Considering this, we used DFT-based models within the molecular fractionation with conjugate caps scheme to evaluate the binding energy features of zinc interacting with the human PBGS. Besides, phylogenetic and clustering analyses were successfully employed in extracting useful information from protein sequences to identify groups of conserved residues that build the ions-binding site. Our results also report a conservative assessment of the relevant amino acids, as well as the benchmark analysis of the calculation models used. The most relevant intermolecular interactions in Zn2+–PBGS are due to the amino acids CYS0122, CYS0124, CYS0132, ASP0169, SER0168, ARG0221, HIS0131, ASP0120, GLY0133, VAL0121, ARG0209, and ARG0174. Among these residues, we highlighted ASP0120, GLY0133, HIS0131, SER0168, and ARG0209 by co-occurring in all clusters generated by unsupervised clustering analysis. On the other hand, the triple cysteines at 2.5 Å from zinc (CYS0122, CYS0124, and CYS0132) have the highest energy attraction and are absent in the taxa Viridiplantae, Sar, Rhodophyta, and some Bacteria. Additionally, the performance of the DFT-based models shows that the processing time-dependence is more associated with the choice of the basis set than the exchange–correlation functional.
Sequencing error profiles of Illumina sequencing instruments
Authors: Stoler Nicholas , Nekrutenko Anton 
Published: March 2021

Abstract
Sequencing technology has achieved great advances in the past decade. Studies have previously shown the quality of specific instruments in controlled conditions. Here, we developed a method able to retroactively determine the error rate of most public sequencing datasets. To do this, we utilized the overlaps between reads that are a feature of many sequencing libraries. With this method, we surveyed 1943 different datasets from seven different sequencing instruments produced by Illumina. We show that among public datasets, the more expensive platforms like HiSeq and NovaSeq have a lower error rate and less variation. But we also discovered that there is great variation within each platform, with the accuracy of a sequencing experiment depending greatly on the experimenter. We show the importance of sequence context, especially the phenomenon where preceding bases bias the following bases toward the same identity. We also show the difference in patterns of sequence bias between instruments. Contrary to expectations based on the underlying chemistry, HiSeq X Ten and NovaSeq 6000 share notable exceptions to the preceding-base bias. Our results demonstrate the importance of the specific circumstances of every sequencing experiment, and the importance of evaluating the quality of each one.
The short- and long-term effects of dietary patterns on cardiometabolic health in adults aged 65 years or older: a systematic review
Authors: Luong Rebecca , Ribeiro Rosilene V , Cunningham Jessica , Chen Siting , Hirani Vasant 
Published: March 2021

AbstractContextCardiometabolic diseases are leading causes of death and morbidity. Aging increases the risk of disease development. Diet has protective and causal effects on cardiometabolic health.ObjectiveTo consolidate the current evidence on the short- and long-term effects of dietary patterns on cardiometabolic health in adults aged ≥ 65 years.Data SourcesThe Medline, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, Cumulative Index to Nursing and Allied Health Literature, Web of Science, Scopus, Global Health, and Pre-Medline databases, along with ClinicalTrials.gov and the World Health Organization International Clinical Trials Registry Platform were searched.Data ExtractionA total of 40 042 records were identified. Quality assessment involved using the revised Cochrane risk-of-bias tool for randomized trials and Joanna Briggs Institute checklists. The certainty of evidence was assessed using Grading of Recommendations, Assessment, Development, and Evaluation.ResultsThirteen articles were included (n = 5 cohort studies and n = 3 randomized controlled trials). The low-fat dietary pattern reduced adiposity; however, no effects were evident for hypertension incidence, composite coronary heart disease incidence (including myocardial infarction, coronary heart disease, and coronary revascularization), high-density lipoprotein cholesterol level, and increased blood pressure in the long term. The Mediterranean dietary pattern resulted in reduced triglyceride levels and systolic blood pressure, and had no effects on diastolic blood pressure and glucose in the short term. Other dietary patterns had inconclusive effects.ConclusionsThe Mediterranean dietary pattern showed the most benefits without harm on cardiometabolic health in older adults. The current body of evidence is small, indicating the need for more research to confirm these findings at a high certainty of evidence, and to include dietary patterns combined with other dietary components, subgroups with cardiometabolic disease or risk factors, longer follow-up, and outcomes that have not yet been investigated. Studies including these factors may help identify the most effective dietary pattern for cardiometabolic health benefits in older adults, to inform future guidelines.Systematic Review RegistrationPROSPERO registration no. CRD42020141400.
What determines the unique spectra of super-Eddington accretors? Origin of optically thick and low-temperature coronae in super-Eddington accretion flows
Authors: Kawanaka Norita , Mineshige Shin 
Published: March 2021

Abstract
The existence of relatively cool (kBT ≲ 10 keV) and optically thick (τ ≳ 3) coronae are inferred above super-Eddington accretion flow such as ultraluminous X-ray sources, GRS 1915+105, and narrow-line Seyfert 1 galaxies, which contrasts with cases in sub-Eddington accretion flows, which are associated with coronae with kBT ∼ 100 keV and τ ∼ 1. To understand their physical origin, we investigate the emission properties of the corona which is formed by the gas blown off the super-Eddington inner disk by radiation pressure. We assume that the corona is heated by the reconnection of magnetic loops emerging from the underlying disk. We show that this radiation-pressure-driven wind can act as an optically thick corona which upscatters thermal soft photons from the underlying disk, and that with a reasonable parameter set we can theoretically reproduce the coronal optical depth and temperature which are inferred by spectral fittings of observational data. By contrast, the coronal optical depth cannot be so high in sub-Eddington cases, since the coronal material is supplied from the disk via evaporation and there is a maximum limit on the evaporation rate. We suggest that low-temperature, optically thick Comptonization should be a key signature of super-Eddington accretion flow.
Estimating costs of hepatitis B vaccination in infants: experimental evidence of the expanded program on immunization in Southern Iran
Authors: Mokhtari Ali Mohammad , Barouni Mohsen , Moghadami Mohsen , Negahdaripour Manica , Mirahmadizadeh Alireza 
Published: March 2021

ABSTRACT

Background
Health costs have increased significantly around the world, and cost assessments have become important. This study aimed to collect cost of the resources used in the national hepatitis B immunization program in Southern Iran.

Methods
Costs were calculated by investigating the available documents as well as consulting with knowledgeable personnel. These costs were collected using the data from Shiraz University of Medical Sciences. According to the health payer’s perspective, the indirect costs of the people were not taken into account. All current and capital costs in year 2017 were calculated and converted to US dollars (USDs).

Results
In 2017, 33 204 children received hepatitis B vaccine. The total cost of the national hepatitis B vaccination program in Shiraz and the cost of vaccination per child were 473 506 and 14.26 USD, respectively. However, the cost of inoculation of hepatitis B vaccine per dose was estimated at 3.20 USD. Personnel costs constituted the highest proportion (53.84%) of total costs.

Conclusions
The cost of hepatitis B vaccination in Iran was lower than other countries. Considering that personnel costs had the largest proportion, it is recommended that proper measures be taken to monitor and modify these costs if necessary.
Disagreement after News: Gradual Information Diffusion or Differences of Opinion?
Authors: Fedyk Anastassia 
Published: March 2021

Abstract
This paper considers the puzzle of increased trading volume around information releases through the lens of canonical models of disagreement. I use a unique data set of clicks on news by key finance professionals to simultaneously measure gradual information diffusion and differences of opinion. I find that neither channel subsumes the other and that the two are complementary in generating trading volume around news events. Their relative strengths depend on the characteristics of the underlying information: gradual information diffusion matters more for straightforward news, while differences of opinion play a larger role around textually ambiguous news. (JEL G12, G14, G41, D84)
Received January 12, 2020; editorial decision: November 24, 2020 by Editor: Jeffrey Pontiff. Authors have furnished an Internet Appendix, which is available on the Oxford University Press Web site next to the link to the final published paper online.
Abatacept in monotherapyvscombined in interstitial lung disease of rheumatoid arthritis—multicentre study of 263 Caucasian patients
Authors: Fernández-Díaz Carlos , Atienza-Mateo Belén , Castañeda Santos , Melero-Gonzalez Rafael B , Ortiz-SanJuan Francisco , Loricera Javier , Casafont-Solé Ivette , Rodríguez-García Sebastián , Aguilera-Cros Clara , Villa-Blanco Ignacio , Raya-Alvarez Enrique , Ojeda-García Clara , Bonilla Gema , López-Robles Alejandra , Arboleya Luis , Narváez Javier , Cervantes Evelin , Maiz Olga , Alvarez-Rivas María N , Cabezas Iván , Salgado Eva , Hidalgo-Calleja Cristina , Fernández Sabela , Fernández Jesús C , Ferraz-Amaro Ivan , González-Gay Miguel A , Blanco Ricardo ,   for the Spanish Collaborative Group of Interstitial Lung Disease Associated with Rheumatoid Arthritis
Published: March 2021

AbstractObjectiveTo assess the efficacy and safety of abatacept (ABA) in monotherapy (ABAMONO) vs combined ABA [ABA plus MTX (ABAMTX) or ABA plus non-MTX conventional synthetic DMARDs (csDMARDs) (ABANON-MTX)] in RA patients with interstitial lung disease (ILD) (RA-ILD).MethodsThis was a restrospective multicentre study of RA-ILD Caucasian patients treated with ABA. We analysed in the three groups (ABAMONO, ABAMTX, ABANON-MTX) the following outcome variables: (i) dyspnoea; (ii) forced vital capacity (FVC) and diffusion capacity of the lung for the carbon monoxide (DLCO); (iii) chest high-resolution CT (HRCT); (iv) DAS28-ESR; (v) CS-sparing effect; and (vi) ABA retention and side-effects. Differences between basal and final follow-up were evaluated. Multivariable linear regression was used to assess the differences between the three groups.ResultsWe studied 263 RA-ILD patients (mean ± s.d. age 64.6 ± 10 years) [ABAMONO (n = 111), ABAMTX (n = 46) and ABANON-MTX (n = 106)]. At baseline, ABAMONO patients were older (67 ± 10 years) and took higher prednisone dose [10 (interquartile range 5–15) mg/day]. At that time, there were no statistically significant differences in sex, seropositivity, ILD patterns, FVC and DLCO, or disease duration. Following treatment, in all groups, most patients experienced stabilization or improvement in FVC, DLCO, dyspnoea and chest HRCT as well as improvement in DAS28-ESR. A statistically significant difference between basal and final follow-up was only found in CS-sparing effect in the group on combined ABA (ABAMTX or ABANON-MTX). However, in the multivariable analysis, there were no differences in any outcome variables between the three groups.ConclusionIn Caucasian individuals with RA-ILD, ABA in monotherapy or combined with MTX or with other conventional-DMARDs seems to be equally effective and safe. However, a CS-sparing effect is only observed with combined ABA.