bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application of pantohematogen dry for treatment of discirculatory disorders in chronic prostatitis (experimental and clinical study)
Authors: Tihonov Igor V. , Tityaev Igor I. , Kasyanov Denis S. , Chekushin Ramil H. 
Published: May 2021

PURPOSE: To study in experiment and in clinical conditions the effectiveness of the preparation pantogematogen dry, obtained from the blood of a maral, for the correction of dyscirculatory disorders in the prostate gland.
MATERIALS AND METHODS: The experimental and morphological part of the work was performed on 90 male Wistar rats with local venous congestion in the small pelvis due to ligation of the internal iliac veins. Animals of the main group (n = 30) underwent enteral correction with dry pantohematogen (in a daily dose of 10 mg per 100 g of animal weight) starting from the 7th day after modeling the disease, the course was 14 days. The rats of the 2nd group (n = 30) after modeling of venous stasis were not treated. Group 3 consisted of intact animals. During the clinical phase of the study, 61 patients with chronic congestive prostatitis were treated. All patients received standard therapy, and patients in the treatment group (n = 30) additionally received highly dispersed aerosol transrectal irrigation with an aqueous solution of pantohematogen, daily, for a course of 10 procedures.
RESULTS AND DISCUSSION: Morphological examination of the prostate gland of laboratory animals with experimental discirculatory prostatitis and its subsequent enteral correction with panthematogen dry indicated significant differences compared with animals of the 2nd group. A tendency towards restoration of the normal structure of the prostate, its metabolism, regional and organ blood and lymph outflow, improvement of the drainage-detoxification and transport activity of its regional lymph nodes was noted. In the clinical part of the study, the effectiveness of the use of pantogematogen in patients with chronic congestive prostatitis was shown. At the end of the course of treatment in patients of the 1st group, the disappearance of pain (in 72.4% of cases) and dysuric (in 86.2% of cases) syndromes was observed, and in the rest a decrease in their intensity. According to the TRUS of the prostate in patients of the 1st group, after treatment in 52% of cases, a decrease in the volume of the prostate was noted.
CONCLUSIONS: The results of an experimental clinical study indicate the prospects for the inclusion of pantogematogen in the complex therapy of patients with chronic congestive prostatitis.
PRODUÇÃO E CARACTERIZAÇÃO DE IOGURTE ADICIONADO DE POLPA DE SERIGUELA
Authors: Araújo Ana Beatriz Medeiros , Azevedo Jonas Ariel de Souza , Rodrigues Thais Jaciane Araújo , Gouveia Deyzi Santos , Véras Ítala Viviane Ubaldo Mesquita 
Published: May 2021

O mercado de alimentos saudáveis e funcionais tem crescido nos últimos anos e um dos produtos que ganhou bastante destaque foi o iogurte, principalmente quando é elaborado com diferentes sabores de frutas. A presente pesquisa foi conduzida com o objetivo de elaborar e caracterizar iogurte adicionado de polpa de seriguela, a fim de desenvolver um novo produto com características típicas da região Nordeste. Foram elaboradas três formulações de iogurte com a polpa de seriguela nas proporções de 15, 25 e 35% da polpa. As análises físico químicas realizadas foram pH, acidez titulável, teor de água, teor de cinzas e proteína. Os valores obtidos para pH (4,01 - 4,15), acidez titulável (0,66 - 0,68%) e proteína (2,05 - 2,16%) não mostraram grandes alterações mediante as diferentes concentrações de polpa de seriguela e, portanto, sem diferença significativas ao nível de 5% de probabilidade pelo teste de Tukey. Os teores de água foram inversamente proporcionais às quantidades de polpa adicionadas, variando de 79,54 a 80,91%. O teor de cinza (0,49 - 0,58%) variou de forma esperada, sendo maior em maiores concentrações de polpa. Portanto, a produção de iogurte adicionado de polpa de seriguela é considerada viável, tendo em vista que contribuirá para a diversificação do setor lácteo e para o melhoramento das características físico-químicas do produto.
Environmental Risk Assessment of Heavy Metals by Exploring Chemical Fractions, Leachability, Bioavailability in Road Dusts from Steel-Industrial City (Anshan), Northeastern China
Authors: Zong Yutong , Xiao Qing , Malik Zaffar , Lu Shenggao 
Published: May 2021

Abstract
This study evaluated chemical fractions, potential leachability, and bio-accessibility of heavy metals (Cr, Cu, Cd, Ni, Pb, and Zn) in road dusts from the steel-industrial city (Anshan), Northeastern China. Chemical fractions of heavy metals were determined using Tessier sequential extraction method. The environmental risk assessment was evaluated using short-term extraction tests: TCLP, PBET, and CaCl2. Sequential extraction analysis reveals that Cr and Ni primarily existed in residual form. The non-residual fraction of heavy metals decreased in the order of Zn (average 57.78%)> Cu (39.16%)> Pb (30.73%)≈ Cd (30.67%)> Ni (19.06 %)> Cr (8.7%%). The results showed that Cd, Cu, Zn and Pb, which were extremely concentrated in potentially mobile fractions, had highly potential environmental risks. The mobility of Cd and Zn was usually higher than those of Cr, Cu, Pb and Ni, which means that Cd and Zn have higher hazardous to ecosystem. The order of bioavailability identified by PBET method was generally Zn>Cd>Pb>Ni>Cu>Cr. There was a significantly relationship between PBET, TCLP-test and bioavailable parts (F1+F2+F3+F4, SUM4) of sequential extraction, respectively. Multiple linear regression analysis indicated that toxicity and bioavailability of heavy metals were not only depended on RDs properties, but also lied on the total heavy metals.
Classification Model for Heart Disease Prediction With Feature Selection Through Modified Bee Algorithm
Authors: Velswamy Karunakaran , Velswamy Rajasekar , Swamidason Iwin Thanakumar Joseph 
Published: May 2021

Abstract
Now-a-days a healthcare field produces a huge amount of data, for processing those data some efficient techniques are required. In this paper, a classification model is developed for heart disease prediction and the attribute selection is carried out through a modified bee algorithm. The prediction of heart disease through models will help the practitioners to make a precise decision about patient health. Heart disease dataset is obtained from the UCI repository. Dataset consists of 76 features and all those seventy-six features have not contributed equal information during the time classification. In the entire attributes, some of the attributes have contributed a large amount of information at the time of classification and some of the attributes have contributed only a small amount of information during the classification task. In this paper, a modified bee algorithm is used to identify the best subset of features from the entire features in the dataset i.e., in the training phase of classification only retain those features that are contributing more information during classification and it will reduce the training time of classifiers. The experiment is analyzed with a obtained reduced subset of features by using the following classifiers such as Support Vector Machine, Navie bayes, Decision tree and Random forest. The experimental result shows that the Support Vector Machine classifier will provide a good classification accuracy, true positive rate, true negative rate, false positive rate and false negative rate compared to Navie bayes and Random forest tree classifier.
Selenium Promotes Sunflower Resistance to Sclerotinia Sclerotiorum by Regulating Redox Homeostasis and Hormonal Signaling Pathways
Authors: Chen Zhiying , Sun Huiying , Hu Ting , Wang Zehao , Wu Wenliang , Liang Yue , Guo Yanbin 
Published: May 2021

Abstract
Sclerotinia wilt of sunflower caused by Sclerotinia sclerotiorum is a devastating disease causing serious loss. Selenium (Se) has a benefit effect to plant in stress tolerance. In this study, sunflower leaves treated by foliar application of Se were inoculated with S. sclerotiorum. Pathogenesis on the inoculated leaves and transcript levels of plant genes involved in redox homeostasis and hormonal signaling pathways were examined. Se could be detected after the foliar application and was mainly transformed to selenomethionine in sunflower. Consequently, Se pretreatment delayed the necrosis development caused by S. sclerotiorum and alleviated the adverse effects derived from pathogen infection by differentially balancing the regulation of enzymes involved in the redox homeostasis. Specially, the cat expression increased to alleviate its downregulation responded to pathogen infection at the earlier infection stage (12 hour post inoculation, hpi) while the pod, gpx, apx, and nox expressions decreased to alleviate their responsive upregulation at the later infection stages (24 and 36 hpi). Se pretreatment enhanced the regulation of genes involved in hormonal signaling pathways, in which the AOC and PAL expressions increased to enhance its upregulation induced by pathogen infection for improving resistant responses at the earlier infection stage (12 hpi), as well as the AOC and PDF expressions increased at the later infection stages (24 hpi). Besides, the EIN2 expression increased to alleviate its downregulation at all of infection stages. Our results suggested that Se plays the beneficial effect on the resistant responses to S. sclerotiorum infection. This study provided a clue to improve the sustainable management of Sclerotinia wilt on sunflower by Se foliar application.
Multi-Hazard Susceptibility Assessment: Case Study – Municipality of Štrpce (Southern Serbia)
Authors: Durlević Uroš , Novković Ivan , Samardžić Ivan , Ćurić Vladimir , Batoćanin Natalija , Valjarević Aleksandar , Lukić Tin 
Published: May 2021

Abstract
The Municipality of Štrpce (Southern Serbia) is an area located within the Šar Mountain National Park, and due to its great ecological importance, it was necessary to analyze the terrain susceptibility to the occurrence of natural hazards. The main goal of this research is to determine the locations that are most susceptible to natural hazards (earthquakes, erosion, torrential flooding, snow avalanches and forest fires) on the territory of the municipality of Štrpce. By utilizing the geographic information systems (GIS), the first step was to analyze seismic hazard for a 475-year return period (VII-VIII MCS for the observed area). The second step was to determine the intensity of erosion and total sediment production using erosion potential model (EPM). The mean erosion coefficient is quantified to 0.34, and the total sediment production is 131.795 m3/year. The third step was the analysis potential of torrential floods using the Flash Flood Potential Index (FFPI). This method indicated that 43.33% of the municipality is highly susceptible, and 18.86% is very highly susceptible to torrential floods. The Avalanches Potential Index (AVAPI) method was used for the fourth step which involved determining the area prone to the occurrence and movement of avalanches. It was determined that 9.1 km2 of the municipality area is susceptible to this type of hazard. The fifth step included the analysis of the terrain susceptibility to the occurrence of forest fires. More than half of the municipal area (52.4%) is highly susceptible, and 8.5% is very highly susceptible to forest fires. Following the five criteria analysis, weight coefficients were assigned for each of the analyzed parameters using the analytical hierarchy process (AHP), giving the result of the total susceptibility of the territory of Štrpce to natural hazards. Results indicated that over 45% of the municipality is highly or very highly prone to various natural hazards. This paper presents a significant step towards better understanding and more adequate management and mitigation of natural hazards not only in the investigated area, but on regional and national levels as well.
Landslide Triggered by Orthogonal Tunnel Excavation and Prevention Measures in Jimei Village, Sichuan Province, China
Authors: wang zhongfu , Liu Han Dong , He Si Ming , Fang Yunfeng 
Published: May 2021

Abstract
The axis of highway tunnels constructed in mountains under complex geological conditions is usually orthogonal to the section of potential landslide. The tunnel construction may lead to landslide, which then may result in the deformation and/or cracking of tunnels. Therefore, it is very important and practical for tunnel projects to study the complex interaction mechanism between orthogonal tunnel and landslide and provide appropriate prevention measures for tunnel. This paper, on the base of geological survey, on-site monitoring and numerical simulation, analyzed the deformation and reason of an ancient landslide revived by tunnel construction and studied the prevention measures for tunnel. The results show that the reason for the revival of the ancient landslide resulted mainly from the tunnel construction through sliding surface, and the ancient landslide is generally stable because most landslide deformation occurred beyond the tunnel and in the upper part of landslide. The numerical simulation was used to optimize the tunnel prevention scheme by the analysis to the stability, stresses and deformation of landslide based on stress-strain control theory. The original anti-slide pile design was cancelled and finally the tunnel is reinforced by upper soil removal and moving upper soil into toe. This tunnel has successfully completed and are under good operation. The used prevention measures were proven to be effective according to the monitoring data about displacements and stress of landslide and tunnel during operation period, and saved about seven million US$. The research results in this paper may offer a beneficial reference to projects with similar geological conditions.
The Relationship Between Staffing Sufficiently by the Workload Indicator of Staffing Needs and HIV Outcomes in Namibia
Authors: Adynski Gillian I , McQuide Pamela , Knafl George , Bock Maria , Hamunime Ndapewa , Jones Cheryl B 
Published: May 2021

Abstract
Background: No study in inpatient or outpatient nurse staffing research have examined nurse staffing using the measure of the World Health Organization’s Workload Indicator of Staffing Needs, despite this being a commonly used tool to make staffing decisions across various healthcare settings around the world. This study aimed to understand the relationship between nurse staffing in HIV clinics and the patient outcomes of viral load documentation and viral load suppression in order to better understand the best ways of staffing nurses to provide the best HIV services to clients. Methods: This study modeled nurse staffing measured as the Workload Indicator of Staffing Needs, with two HIV outcomes of viral load documentation and viral load suppression in remotely located 66 hospitals, health centers and clinics in Northern Namibia. Various control variables were taken into account. Results: Sufficient nurse staffing based on the Workload Indicator of Staffing Needs was associated with better viral load documentation, however overly sufficient staffing made no difference on viral load documentation. There was no association between sufficient staffing by the Workload Indicator of Staffing Needs and viral load suppression. Conclusions: Our findings suggest that staffing sufficiently by the Workload Indicator of Staffing Needs was associated with better HIV outcomes of viral load documentation and viral load suppression at the facility level. This suggests that policy makers should continue using the Workload Indicator of Staffing Needs tool to staff their clients in order to have the best HIV outcomes possible at their facilities.
Influence of Organic Ammonium Derivatives on the Equilibria Between of NH4+, NO2- and NO3- Ions in River Waters
Authors: Spataru Petru 
Published: May 2021

Abstract
The braking effect of the ammonium derivatives on the natural aquatic environment varies dramatically with the number and nature of organic radical substitutions at nitrogen atom, particularly with their structure, composition and genesis. The most common discrepancy in their toxic effect are showing the natural and synthetic amines. For instance, the values of the maximum allowable concentration (MAC) of the derivatives of the natural origin for drinking water exceed the MAC of the synthetic ones by two orders. On the other hand, it has been found out that 1- naphtylamine (1-NA) inhibitory effect is associated to its toxicity. The Diethylamine (DEA) braking impact on the nitrification process is effectively lower than that of the toxicity. Our experiments show that the carbon-radicals of organic amines act as reducing agents. It is found that DEA decomposition leads to a high NH4+ ions (approx. 3.8 mg/L ammonium nitrogen) concentration in river water samples. By laboratory simulations two types of fixations by microbial organisms have been established: 1) absorption-desorption, the hydromicrobiotic reaction to ammonium (HMBRA) at the instantaneous increase of the concentration of ammonium ion in the river water (so-called shock/stress effect); 2) nitrogen fixation stimulated by a certain concentration (0.05mg/L) of a 1-NA and other amines.
Five Weeks of Yuishinkai Karate Training Improves Balance and Neuromuscular Function in Older Adults
Authors: Mustafa Hajer , Harrison Aimee , Sun Yao , Pearcey Gregory E. P. , Follmer MSc. Bruno , Nazaroff Benjamin M. , Rhodes Ryan E. , Zehr E. Paul 
Published: May 2021

Abstract
Background: To test the efficacy of a documented 5-week karate training intervention for rehabilitation and neuroprotection in older adults. Methods: Sixteen older adults (8 male, 8 female, age 59-90y), with or without chronic conditions, participated a 5-week karate training intervention. Dynamic balance, hand grip, ankle plantarflexion force, Timed Up and Go (TUG), and spinal cord excitability (via the soleus H-reflex) were assessed pre- and post-intervention. Results: Participants completed 2437 steps, 1762 turns, 3585 stance changes, 2047 punches, 2757 blocks, and 1253 strikes. Karate training improved dynamic postural performance. The group average time for dynamic postural reaction was reduced (time to target (-13.6%, p = 0.020) and time to center (-8.3%, p =0.010)). TUG was unchanged when considering the entire group (p=0.779), but reductions were found in 5 neurologically intact older adults (-4.5 to -8.6%; p<0.05) and increased for 1 Parkinson’s Disease participant (3.8%, p<0.05). Strength increased in left arm (7.9%, p=0.037), right leg (28.8%, p=0.045), and left leg (13.3%, p=0.024) for the group. Spinal cord excitability remained unchanged across the group but 3 neurologically intact older adults (215.4%, 47.9%, -35.9%; p<0.05) and 2 Parkinson’s Disease participants (152.4%, 195.3%; p<0.05) had modulated H-reflex amplitudes. Conclusion: 5-weeks of karate training delivered in a fashion to mimic community-level programs provided an effective therapeutic “dose” to improve balance and strength in older adults. Whole-body training embodied in martial arts enhanced neuromuscular function and postural integration. Further quantitative work should explore threshold dose and development of martial arts interventions as functional fitness for older adults.
Effect of Different Management Techniques on Bird Assemblages on Rice Fields in the Republic of Korea
Authors: Choi Green , Do Min Seock , Son Seok-Jun , Nam Hyung-Kyu 
Published: May 2021

Abstract
Many bird species rely on the ecological functions of rice field microhabitats. However, recent intensive practices are causing rice fields to provide fewer suitable habitats. This study examined bird microhabitat usage and the effects of intensive use of chemical substances on it. Eco-friendly and conventional rice fields were surveyed from January 2014 to December 2016, and the species presence, the number of birds, and the location of observed microhabitats were recorded. It was found that shorebirds and herons used more eco-friendly rice paddies with fewer or no chemical substances, while waterfowl used the paddy microhabitat more than the other microhabitats, regardless of the amount of chemical substances used. It was confirmed that land birds used ditches or roads in conventional rice fields more than those in fields that used chemical substances. Chemical substances affected bird assemblages differently. Consequently, bird assemblages used habitats differently depending on the farm crop cultivation as well as food abundance. These results provided valuable information useful for managing rice fields that serve as habitats for birds.
Prevalence of Oral and Pharyngeal Cancers and the Relationship Between Tumour Size and Lymph Node Metastases in Oral Cancer.
Authors: Omar Abdullah , Rmman Mohammad , Hafi Madiha Al , Al-Masalmeh Mohammad Sadek , Nahas Louei Darjazini 
Published: May 2021

Abstract
Background: the study aimed at studying the incidence and prevalence rates of oral and pharyngeal cancer and their distribution according to gender, tumour size, histological type and chief complaint. We also tackled the relationship between the tumour size and the metastasis to the regional lymph nodes.Materials and Methods: This cohort retrospective study was done in Al-Mouasat hospital from January 2017 to June 2020. The population included patients with oral or pharynx cancer who were admitted to the Ear, Nose, Throat department.Results: The total participants were 96 cases. The median age was 57 year. The most common tumour location was oral tumour 58.3%, and the most common chief complaint about oral tumour was mass by 62.5%. while nasopharynx cases most commonly came with neck mass 68.2%. 50% was the percentage of dysphagia that was the most common complaint. Squamous cell carcinoma (SCC) was the most common histologic type < 90% of the oral, oropharynx, and hypopharynx cases. About the classification of the tumour due to its subsite 33.9% of the oral cases were in lip and especially the lower one. Whereas, oropharynx most frequent tumour site was the tonsil (50%). we found statistical evidence for the relationship between the tumour size (T) and the metastasis to the regional lymph node (N) in oral cancer.Conclusion: Oral and pharyngeal cancer is a very important issue. And according to our paper, the most frequent cancer was oral cancer and especially lower lip tumour. oral cancer presents with mass. whereas, the nasopharyngeal cancer presentation was neck mas. The most common histological type was SCC. And we reached a relationship between the T and N in oral cancer
Utilizing Patient-specific 3D Printed Guides for Graft Reconstruction in Thoracoabdominal Aortic Repair
Authors: Kim Taehun , Hong Dayeong , Ock Junhyeok , Park Sung Jun , Rhee Younju , Lee Sangwook , Kim Guk Bae , Yang Dong Hyun , Kim Joon Bum , Kim Namkug 
Published: May 2021

Abstract
In thoracoabdominal aortic aneurysm repair, repairing the visceral and segmental arteries is challenging. Although there is a pre-hand-sewn and multi-branched graft based on the conventional image-based technique, it has shortcomings in precisely positioning and directing the visceral and segmental arteries. Here, we introduce two new reconstruction techniques using patient-specific 3D-printed graft reconstruction guides: 1) model-based technique that presents the projected aortic graft, visualizing the main aortic body and its major branches and 2) guide-based technique in which the branching vessels in the visualization model are replaced by marking points identifiable by tactile sense. We demonstrate the effectiveness by evaluating conventional and new techniques based on accuracy, marking time requirement, reproducibility, and results of survey to surgeons on the perceived efficiency and efficacy. The graft reconstruction guides cover the segmentation, design, fabrication, post-processing, and clinical application of open surgical repair of thoracoabdominal aneurysm, and proved to be efficient for accurately reconstructing customized grafts.