bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adherence to Medical Treatment in Elderly Patients with Coronary Artery Disease in the Settings of Primary Outpatient Care
Authors: Zyryanov S. K. , Fitilev S. B. , Vozzhaev A. V. , Shkrebneva I. I. , Shindryaeva N. N. , Klyuev D. A. , Stepanyan L. N. , Lutsenko A. M. , Tsai A. T. , Danilova A. A. 
Published: May 2021

Aim. To study medication adherence in elderly patients with coronary artery disease (CAD) in primary care practice.Material and methods. The study conducted in out-patient clinic of Moscow city. 293 elderly (≥65 years) patients with established CAD included. The following patient data obtained via electronic medical record system: demography, medical history, modifiable risk factors and prescribed pharmacotherapy. Level of medication adherence measured by Morisky scale (MMAS-8) via telephone survey.Results. According to Morisky scale high adherence was identified in 146 (49.8%) elderly patients, moderate adherence – in 99 (33.8%) patients, low adherence – in 48 (16.4%) patients. Analysis of specific questions of the scale done in non-adherent patients revealed signs of unintentional non-adherence due to forgetfulness (45.9%) and signs of intentional non-adherence due to patients feeling worse (35.8%) or better (28.4%). By means of dichotomic interpretation of Morisky scale results the population under research was divided into two groups: 147 (50.2%) non-adherent patients and 146 (49.8%) – totally adherent patients. These groups were comparable in terms of sex (female 71.2 vs 68.0%; p>0.05) and age (median 73.5 vs 73.0 years; p>0.05) distribution, and medical history: myocardial infarction (39.0% vs 38.8%), atrial fibrillation (37.0 and 41.5%), chronic heart failure (90.4% vs 91.2%), diabetes (26.7% vs 24.5%). There were fewer smokers in adherent group (0.7% vs 6.5%; p<0.05). As primary antianginal pharmacotherapy adherent and non-adherent patients were equally prescribed beta-blockers (75.3% vs 75.5%; p>0.05). Drugs that improve prognosis were also prescribed comparably: antiplatelets (66.4% vs 61.9%; p>0.05), anticoagulants (36.3% vs 44.9%; p>0.05), statins (82.2% vs 79.6%; p>0.05), renin-angiotensin system inhibitors (89.0 and 87.8%; p>0.05). Adherent patients had lower mean values of lipids: total cholesterol (4.7±1.2 vs 5.2±1.4 mmol/l; p<0.05) and low density cholesterol (2.4±0.9 vs 2.8±1.2 mmol/l; p<0.05). Non-adherent elderly patients made more visits to general practitioner (median 5 vs 3 visits; p<0.05). Share of patients receiving drugs within supplementary pharmaceutical provision program was comparable in both groups (53.7% vs 50.7%; p>0.05).Conclusion. Half of elderly patients with CAD are non-adherent to treatment in primary care setting. Medical history and structure of pharmacotherapy do not influence level of adherence in this population. Among adherent patients fewer individuals smoke and mean values of lipids are lower. Non-adherent elderly patients cause higher load on general practitioner, supplementary pharmaceutical provision program provided no better adherence in the population under research.
Anticoagulant Therapy in Patients with Non-valvular Atrial Fibrillation in Real Clinical Practice: in Appropriate Dose Reductions
Authors: Ionin V. A. , Bliznuk O. I. , Baranova E. I. , Shlyakhto E. V. 
Published: May 2021

Aim. To study the frequency of administration of direct oral anticoagulant (DOACs) in doses recommended and not recommended by the instructions of the drugs in non-valve atrial fibrillation (AF) patients.Material and methods. 10663 case histories of patients hospitalized for 5 years (2014-2018) were studied, 1307/10663 (12,3%) case histories of patients with AF were selected. In patients with AF, the risk of stroke and systemic embolism, the risk of bleeding, the anticoagulant therapy (ACT) recommended at the prehospital stage and its adequacy was evaluated.Results. 1 261/1 307 (96,5%) patients had a non-valve AF. The risk of stroke and systemic embolism was 4,7±1,5 (CHA2DS2-VASс), 97,5% of patients with non-valve AF (1229/1261) needed ACT. Only 665/1229 (54.1%) patients with AF received ACT at the time of hospitalization and 578/1229 (47,0%) of patients did not receive ACT. Before hospitalization 281/665 (42,3%) patients received vitamin K antagonist (warfarin). The international normalized ratio in the target range (2,0-3,0) was in 111/281 (39,5%) patients. 57,7% (384/665) outpatients with AF received NOAC: rivaroxaban - 180/384 (46,9%) patients, dabigatran etexilate - 110/384 (28,6%) patients, apixaban - 94/384 (24,5%) patients. Inappropriate reduced doses of DOAC were revealed in 68/384 (17,7%) patients: apixaban - 23,4%, dabigatran - 16,4% and rivaroxaban - 15,6% (p>0,05).Conclusion. In real clinical practice 42,3% AF patients used warfarin, only 39,5% of them had INR in target values. DOAC in inappropriate reduced doses used 17,7% patients.
Analysis of Anticoagulant Therapy in the Elderly Patients, in Clinical Practice of Family Medicine Centers in the Kyrgyz Republic
Authors: Mamatov S. M. , Kanat kyzy B. , Musakeev A. O. , Kinderbaeva N. K. , Tagaev T. J. 
Published: May 2021

Aim. To study the current state of the anticoagulant's prescription in elderly and senile patients with atrial fibrillation in the clinical practice of family medicine center, in the southern regions of the Kyrgyz Republic.Material and methods. Of the 1974 ambulatory medical observation cards, 470 patients with atrial fibrillation were selected who had indications for prescribing antithrombotic therapy (87 [18.5%] men and 383 [81.5%] women; 212 [45.1%] urban residents and 258 [54.9%] rural residents). The average age was 66.9±10.2 years. The analysis included data from 387 patients who received anticoagulant therapy. The frequency of prescribing antithrombotic therapy has been studied.Results. There were indications for anticoagulant therapy in 387 patients. Anticoagulants were taken by 167 (43.2%) patients, antiplatelet agents - 196 (50.6%), no therapy - 24 (6.2%). Anticoagulant therapy in 153 patients included warfarin, while only 11.8% had adequate INR control after one year of follow-up. Rivaroxaban was prescribed in 14 (8.4%) patients. 50% of patients had antiplatelet agents instead of anticoagulants, which were mainly prescribed by therapists of rural family medicine centers.Conclusion. In the southern regions of the republic, an unfavorable situation is observed with the prescription and management of elderly and senile patients on anticoagulant therapy. It is necessary to continue the research across the country in order to obtain a complete and real picture of the problem, and to develop a unified and relevant recommendation.
Comorbidities and Percutaneous Coronary Intervention in Elderly Patients with Acute Coronary Syndrome
Authors: Gilyarov M. Yu. , Konstantinova E. V. , Atabegashvili M. R. , Solntseva T. D. , Anichkov D. A. , Kostina А. N. , Polybin R. V. , Udovichenko A. E. , Svet A. V. 
Published: May 2021

Aim. To assess comorbidities in elderly patients with acute coronary syndrome (ACS) and to analyze patient subgroups with different treatment strategies in the Regional Vascular Center (RVC).Material and methods. The prospective study included 205 patients with confirmed ACS 75 years and older, the mean age was 81±4.9 years, and 68% were women. ST segment elevation myocardial infarction (STEMI) was diagnosed in 46 (22.4 %) patients, non-ST segment elevation myocardial infarction (NSTEMI) was diagnosed in 159 (77,6 %) patients. The Charlson Comorbidity Index (CCI) was calculated in every patient. Early outcomes were defined as those assessed during hospital stay. Late outcomes were assessed at 6 months after the discharge using phone calls and/or clinic visits. All patients provided written informed consent.Results. Percutaneous coronary intervention (PCI) was performed in 42% of patients. In patients with STEMI and NSTEMI PCI was performed in 73% and 32%, respectively. Mean CCI score was 7.9 points: 7.6 points in men and 8.04 in women. Patients with STEMI had higher CCI score than NSTEMI patients (p<0.01): 8.1 points and 7.1 points, respectively. Patients who underwent PCI had lower CCI score (7.2 points) than patients in non-PCI group (8.2 points; p<0.05). Patients with STEMI in PCI and non-PCI groups had significant difference in CCI score (p<0.05): 7.4 and 8.4 points, respectively. Mean CCI score in patients who died in hospital was 8.5 while discharged patients had 7.6 points (p<0.01). In 6 months 13 patients (6.3%) died, their mean age was 84.9 years, mean CCI was 9 points, PCI was performed in 3 (23%) patients.Conclusions. Elderly patients with ACS had high comorbidity level assessed by CCI score. Higher CCI score was associated with PCI non-performance in elderly patients. Elderly patients with STEMI had higher CCI score than patients with NSTEMI which was significantly associated with PCI non-performance. Patients who died in hospital or in 6 months after the ACS onset had higher CCI score than other elderly patients with ACS.
The Efficacy of Thrombolytic Therapy in Inferior Myocardial Infarction with Damage to the Right Ventricular
Authors: Mazur E. S. , Mazur V. V. , Kuznetsova N. S. , Rabinovich R. M. , Myasnikov K. S. 
Published: May 2021

Aim. To study the results of thrombolytic therapy and accuracy of electrocardiographic assessment of thrombolysis efficiency in inferior myocardial infarction with and without right ventricular lesion.Material and methods. The118 patients with inferior myocardial infarction were included in this study. They received TLT in the first 12 hours of the disease. The dynamics of ST-segment in 90 minutes from the TLT start and coronary angiography data were analyzed.Results. Right ventricular myocardial infarction (RVMI) was diagnosed in 49 (41.5%) of 118 patients by echocardiography. Patients with and without RVMI did not differ in age, gender and comorbidities, but patients with RVMI were more likely to have arterial hypotension, atrioventricular block, and atrial fibrillation. All patients with RVMI had occlusion of the right coronary artery (RCA) in the proximal (34.7%) or medial segment (65.3%). Occlusion of the circumflex coronary artery was found in 20 (29.0%) patients without RVMI, and RCA occlusion - in other patients. The infarction-associated artery blood flow equal TIMI 2-3 was found in 17 (34.7%) patients with RVMI and in 46 (66.7%) patients without RVMI (p<0.005). ST-segment decrease by 50% or more in 90 minutes from the TLT was found in 35 (71.4%) patients with RVMI and in 49 (71.0%) patients without RVMI (p>0.05). The false-positive assessment of thrombolysis efficiency was noted in patients with and without RVMI in 21 (42.9%) and 11 (15.9%) cases (p <0.005), respectively. There were no false-positive assessments in patients with RVMI when using ST-segment decrease to the isoline.Conclusion. TLT should be considered effective in patients with inferior myocardial infarction with the right ventricle lesion, if ST-segment decreases to isoline in 90 minutes from the TLT start.
Water resource R&D efficiency in Korea – toward sustainable integrated water resources management
Authors: Cho Inkyung , Heo Eunnyeong , Park Jungkyu 
Published: May 2021

Abstract
In 2018, the Korean government established a legal foundation for integrated water management. Accordingly, various measures for integrated water management were taken, and water research and development (R&D) is being integrated with the Ministry of Environment. Strategic planning is needed for the efficient implementation of integrated large-scale water R&D. This study aims to analyze the efficiency of large-scale R&D programs in the field of water resources conducted by the Korean government and identify matters of priority for planning future water resources R&D programs. An empirical analysis was conducted using data envelopment analysis (DEA), in particular, a non-radial slack-based measure (SBM) model was applied to consider slacks in the input and output variables. The results showed that the efficiency of collaborative R&D projects was relatively lower than that of single projects. Further, corporate research institutes, which are typically considered as the leaders of technological innovation, were found to have conducted projects less efficiently than universities or public research institutes. Based on these results, this study recommends that: (1) a system to maximize the advantages of collaborative research should be established; (2) institutional support to enhance the enterprise's innovative activities should be prepared; and (3) comprehensive, long-term planning for integrated water management should be implemented.
Crop water productivity and yield response of two greenhouse basil (Ocimum basilicum L.) cultivars to deficit irrigation
Authors: Goldani Morteza , Bannayan Mohammad , Yaghoubi Fatemeh 
Published: May 2021

Abstract
This two-year study aimed to determine the most appropriate irrigation scheduling and crop water productivity (CWP) of basil plant under controlled conditions in Ferdowsi University of Mashhad, Iran. The experimental layout was a split-plot design with three replications. Three deficit irrigation (DI) levels (DI0: 100%, DI30: 70% and DI60: 40% of the field capacity) and two basil cultivars (Green and Purple) were applied to main and subplots, respectively. The results showed that there was a decrease in yield and an increase in CWP for fresh leaves and fresh and dry herb by decreasing the irrigation water. However, a significant difference between fresh leaves and fresh and dry herb yield of DI0 and DI30 treatment was not observed. The Green basil had higher leaves and herb yield and CWP than the other cultivar. A polynomial relationship was established between fresh leaves yield and crop evapotranspiration; however, the yield response factor (Ky) indicated a linear relationship between the relative reduction in crop evapotranspiration vs. the relative reduction in yield. The Ky values were obtained as 0.70 and 0.76 for Green and Purple basil, respectively. The results revealed that the irrigation regime of 30% water saving could ensure acceptable yield of basil plant and increase in CWP, especially for the Green basil cultivar.
The anaerobic biodegradation of emerging organic contaminants by horizontal subsurface flow constructed wetlands
Authors: Ilyas H. , Masih I. , van Hullebusch E. D. 
Published: May 2021

Abstract
The horizontal subsurface flow constructed wetland (HFCW) is widely studied for the treatment of wastewater containing emerging organic contaminants (EOCs): pharmaceuticals, personal care products, and steroidal hormones. This study evaluates the performance of HFCW for the removal of these types of EOCs based on the data collected from peer-reviewed journal publications. In HFCW, anaerobic biodegradation is an important removal mechanism of EOCs besides their removal by the filter media (through sedimentation, adsorption, and precipitation) and plant uptake. The average removal efficiency of 18 selected EOCs ranged from 39% to 98%. The moderate to higher removal efficiency of 12 out of 18 selected EOCs in HFCW indicates the suitability of this type of constructed wetland (CW) for the treatment of wastewater containing these EOCs. The reasonably good removal (&gt;50% in most of the cases) of these EOCs in HFCW might be due to the occurrence of anaerobic biodegradation as one of their major removal mechanisms in CWs. Although the effluent concentration of EOCs was substantially decreased after the treatment, the environmental risk posed by them was not fully reduced in most of the cases. For instance, estimated risk quotient of 11 out of 18 examined EOCs was extremely high for the effluent of HFCW.
ANALISIS EFEKTIVITAS APLIKASI E-ARSIP SEBAGAI MEDIA TEMU KEMBALI INFORMASI
Authors: Saeroji Ahmad , Andriyati Rizka , Muhsin Muhsin 
Published: May 2021

Abstrak: Analisis Efektivitas Aplikasi E-Arsip Sebagai Media Temu Kembali Informasi. Perkembangan Teknologi Informasi dan Komunikasi berpengaruh terhadap cara pengelolaan surat masuk, surat keluar dan kearsipan. Salah satu aplikasi yang digunakan di Kantor Imigrasi Kelas II Non TPI Pati adalah aplikasi SISUMAKER. SISUMAKER merupakan sebuah aplikasi pengelolaan surat dan pengarsipan secara digital. Tujuan dilakukannya penelitian ini adalah untuk mengetahui efektivitas SISUMAKER sebagai sarana temu balik informasi arsip. Penelitian ini menggunakan deskriptif kuantitatif dengan metode analisis deskriptif. Data hasil penelitian dianalisis dengan metode deskriptif berdasarkan pada data yang diperoleh. Data diperoleh melalui observasi, wawancara, dan dokumentasi. Populasi dan sampel digunakan penelitian ini merupakan seluruh arsip yang telah dikelola Kantor Imigrasi Kelas II Non TPI Pati sejak tahun 2018-2020 berjumlah 10.233. Analisis data dilakukan dengan persamaan recall-precision yaitu dengan mendata semua arsip, kemudian disajikan dalam bentuk tabulasi dan diinterpretasikan sebagai jawaban atas permasalahan penelitian. Hasil penelitian menyatakan bahwa aplikasi SISUMAKER mendekati ideal dan efektif dalam menemukan kembali informasi atau arsip. Kata kunci: efektivitas, aplikasi, e-arsip, informasi, recall-precision Abstract: Analysis of E-Archive Application Effectiveness as Media of Retrieval of Information. The development of information and communication technology affects the way in which incoming, outgoing mail and archives are managed. One of the applications used in the Class II Non TPI Pati Immigration Office is the SISUMAKER application. SISUMAKER is a digital mail management and archiving application. The purpose of this study was to determine the effectiveness of SISUMAKER as a means of archival information. This research uses descriptive quantitative with descriptive analysis method. The research data were analyzed using descriptive methods based on the data obtained. Observation data, interviews, and documentation. The population and sample of this study are all archives that have been managed by the Class II Non TPI Pati Immigration Office since 2018-2020 which were managed 10,233. Data analysis was carried out using the recall-precision equation, namely by recording all archives, then presented in tabulated form and interpreted as an answer to the research problem. The results of international research show that the SISUMAKER application is effective and effective in recovering information or archives. Keywords: effectiveness, application, e-archive, information, recall-precision
DETERMINAN AUDITOR SWITCHING SECARA VOLUNTARY
Authors: Umdiana Nana , Siska Siska 
Published: May 2021

Abstrak: Determinan Auditor Switching secara Voluntary. Penelitian ini bertujuan untuk menganalisis pengaruh pergantian manajemen, Qualified opinion (Opini Wajar Degan Pengecualian) dan Ukuran perusahaan yang berpengaruh terhadap Auditor Switching (Pergantian Auditor) secara voluntary (sukarela) pada perusahaan Pertambangan yang terdaftar di Bursa Efek Indonesia tahun periode 2015-2018. Jenis penelitian ini adalah penelitian kausal asosiatif dan Jenis data yang digunakan adalah data sekunder. Analisis data menggunakan SPSS versi 25 .Populasi dalam penelitian ini adalah perusahaan-perusahaan sub pertambangan yang terdaftar di Bursa Efek Indonesia tahun 2015 - 2018. Namun untuk beberapa variabel dibutuhkan data tahun sebelumnya. Metode pengumpulan data yang digunakan dalam penelitian ini adalah purposive sampling, yaitu berdasarkan kriteria yang telah ditentukan. Sebanyak 6 perusahaan yang digunakan sebagai sampel perusahaan. Data dianalisis dengan statistik deskriptif dan regresi logistic. Berdasarkan hasil dari analisis menunjukkan bahwa pergantian manajemen, qualifiedopini , dan ukuran perusahaan tidak berpengaruh terhadap auditorswitching secara voluntaryKata Kunci : pergantian Auditor, pergantian manajemen, SukarelaAbstract: Determinants Of Voluntary Auditor Switching. This research has a purpose to analize the effect of management changes, qualified opinion and size of clien to auditor switching voluntary in mining companies listed in the Indonesia Stock Exchange in 2015-2018 .The type of this research was associativecausal and the type of data used is secondary data. Data analysis uses SPSS version 25. The population in this research are sub-mining companies listed on the Indonesia Stock Exchange in 2015 - 2018.However, for some variables the previous year's data is needed. Data collection method used in this research was purposive sampling, which is based on predetermined criteria. A total of 6 companies were used as sample companies. Data were analyzed using descriptive statistical analysis and logistic regression.The results of analize showed that management changes, qualified opinion, and size of clien do not affect to auditor switching voluntaryKeywords: Auditor switching, countary, management changes, Voluntary
THE EFFECT OF FINANCIAL KNOWLEDGE AND THE USE OF E-MONEY TOWARD FINANCIAL BEHAVIOR OF UNDERGRADUATE STUDENTS FACULTY OF ECONOMICS YOGYAKARTA STATE UNIVERSITY
Authors: Safitri Meyliana , Sari Ratna Candra 
Published: May 2021

Abstract: The Effect of Financial Knowledge and The Use of E-Money Toward Financial Behavior of Undergraduate Students Faculty of Economics Yogyakarta State University. This study aims to determine the influence of (1) Financial knowledge toward financial behavior of undergraduate students Faculty of Economics, Yogyakarta State University. (2) Knowing the influence of the use of e-money toward financial behavior of undergraduate students Faculty of Economics, Yogyakarta State University. This research was comparative causal study. The study sample was 217 respondents of the Faculty of Economics, Yogyakarta State University students. Samples were taken using purposive sampling technique. The data analysis technique used is multiple linear regression analysis test. The result of this study show that (1) Financial knowledge has a positive effect on financial behavior of undergraduate students Faculty of Economics, Yogyakarta State University. (2) The use of E-money has a negative effect on financial behavior of undergraduate students Faculty of Economics, Yogyakarta State University. Keywords: Financial Knowledge, E-money, Financial BehaviorAbstrak: Pengaruh Pengetahuan Keuangan, Dan Penggunaan E-Money Terhadap Perilaku Keuangan Mahasiswa S1 Fakultas Ekonomi Universitas Negeri Yogyakarta. Penelitian ini bertujuan untuk mengetahui pengaruh (1) pengetahuan keuangan terhadap perilaku keuangan mahasiswa S1 Fakultas Ekonomi Universitas Negeri Yogyakarta. (2) Mengetahui pengaruh penggunaan e-money terhadap perilaku keuangan mahasiswa S1 Fakultas Ekonomi Universitas Negeri Yogyakarta. Penelitian ini merupakan penelitian hubungan kausal. Sampel penelitian ini adalah 217 responden mahasiswa Fakultas Ekonomi Universitas Negeri Yogyakarta. Sampel diambil menggunakan teknik purposive sampling. Teknik analisis data menggunakan uji analisis regresi linear berganda. Hasil penelitian menunjukan bahwa (1) Pengetahuan Keuangan, berpengaruh positif terhadap Perilaku Keuangan Mahasiswa S1 Fakultas Ekonomi Univeristas Negeri Yogyakarta. (2) Penggunaan e-money berpengaruh negatif terhadap perilaku keuangan mahasiswa S1 Fakultas Ekonomi Universitas Negeri Yogyakarta.Kata kunci: Pengetahuan Keuangan, E-money, Perilaku Keuangan.