bluuebunny/crossref_metadata_2025_split huggingface dataset:
A clinic biochemical study of status of fasting serum insulin and lipid profile in PCOS patients and to determine correlation between BMI and HOMA index in PCOS patients
Authors: Yadav Sumitra , Gupta Manisha 
Published: August 2021

The importance of insulin resistance, compensatory hyperinsulinemia, and its effects, many of which have adverse effects on both the metabolic and reproductive organs. Treatment options for insulin resistance/hyperinsulinemia include lifestyle changes, exercise, weight loss, and or the use of thiazolidinediones (TZDs) or metformin. Weight loss measures are essential to the treatment of this condition. Lifestyle, exercise, and dietary changes, weight loss has been shown to reduce hyperandrogenism, increase ovulation and pregnancy rates, and improve immune conflict. Numerous studies have suggested that metformin plays an important role in the treatment of PCOS including restoring ovulation, weight loss, reducing androgen cycle levels, reducing the risk of miscarriage, and reducing the risk of gestational diabetes (GDM).PCOS patients may develop severe dyslipidemia, such as increased LDL-C and TG levels and decreased HDL-C levels associated with hyperandrogenism, IR, and chronic inflammation. Therefore, statins are widely used in the treatment of PCOS patients to reduce inflammation, oxidative stress, hyperandrogenemia, and other metabolic disorders. Statins have been reported to block HMG-CoA inhibiting mevalonate synthesis, which is a necessary substrate for cholesterol production and can be used to synthesize other important lipid links, therefore, statins can improve lipid status and hyperandrogenism.
Pregnancy outcomes in women presenting with single versus multiple episodes of reduced fetal movements: A prospective observational study
Authors: Pallavee P , Podili Prudvi Rani , Samal Rupal , Ghose Seetesh 
Published: August 2021

Fetal movement counting may assist clinicians to intervene at the right time and improve perinatal outcomes, but may sometimes cause unnecessary interventions. A recent Cochrane review in 2015 concludes that there is insufficient evidence to influence practice. This prospective observational study was conducted to evaluate pregnancy outcomes of 103 pregnant women presenting with primary complaints of reduced fetal movements to our Institute. All patients underwent ultrasonography (USG) and non-stress testing (NST) as preliminary investigations and were followed up till delivery. Labor outcomes like onset of labor, mode of delivery, neonatal outcomes like APGAR scores, admission to NICU for &#62; 24 hours, birth weight, neonatal complications and maternal complications were noted. One hundred and three pregnant women presented with reduced fetal movements, of whom, 65% were term primigravida between the ages of 18-26 years. 47.5% belonged to the high risk pregnancy group. The rates of admission (62.1%), induction (77.7%) and cesarean section (43.7%) were high in this group. Pregnancy outcomes did not differ between single and multiple episodes of reduced fetal movements. Based on risk categorization we found that a single episode of reduced fetal movement was associated with approximately 70% good neonatal outcomes, whereas there was 50% risk of adverse neonatal outcomes with multiple episodes. Though this was clinically significant we could not establish statistical significance for this result. Reduced fetal movement can occur in both low and high risk pregnant population. Pregnancy outcomes between single and multiple episodes of RFM were not significantly different.
Influence of demographic profiles and spinal anaesthesia procedures on patients with treated and untreated coffee related to post dural puncture headache pain score
Authors: Jyotsana  , Sreeja L  
Published: August 2021

Post Dural Puncture Headache (PDPH) is an iatrogenic complication of spinal anaesthesia (SP) and has devastating consequences. To assess the effect of Coffee on occurrence of PDPH in post-operative patients of Interventional and control groups by comparing the mean PDPH pain scores related to demographic profiles and spinal anaesthesia procedures. An experimental approach in which 60 patients were recruited from the accessible population and was further allocated randomly to Interventional (30) and Control (30) groups. The patients were compared the demographical profiles viz. age, education and marital status and spinal anaesthesia procedures viz. surgery types, needle size and amount of fluid intake related to PDPH pain scores by Numerical Rating Scale after administration of three doses (130mg caffeine in 150ml) of coffee at intervals of 12hrs in Interventional group and only routine care in control group. The main findings in this study were that the incidence of PDPH is lower in Interventional group compared to control group with statistically significant difference (P&#60;0.001) but it is not influenced by demographic profiles as well as SP procedures in Interventional group compared to control group without statistically significant observation after 24 hrs, 48hrs and 72hrs NRS pain score, respectively.The use coffee is an effective, safe, non-invasive treatment for prevention of PDPH.
Antenatal umbilical cord coiling index as a predictor of pregnancy outcome
Authors: John Lopamudra B , Aanandini Takkellapati , Rathod Setu 
Published: August 2021

: Fetal compromise as a major contributor to neonatal morbidity is of great concern for obstetricians. Antenatal risk assessment profiles are often insufficient in picking up these cases and hence need to be improved. Antenatal Umbilical cord Coiling Index (AUCI) is one such potential predictor which helps in identifying pregnant women who need close antepartum and intrapartum monitoring. It is determined by ultrasonogram antenatally and noted to be fixed throughout the pregnancy. This study aims at determining the association between AUCI and pregnancy outcome.: This was a hospital based prospective analytical study conducted in a tertiary care centre in Pondicherry from January 2019 to May 2020. 207 pregnant women were included in the study and Colour doppler was performed and AUCI was noted. Participants were followed until delivery and pregnancy outcomes were noted.: Chi square and Fischer exact test: In the present study, among 207 subjects, 166 had normal AUCI i.e., 0.41 to 0.61. Hypocoiling was noted in 20 (&#60; 0.41) and hypercoiling in 21(&#62;0.61) subjects. Hypocoiling was associated with hypertension and oligohydramnios in10% cases each. Nonreasssuring fetal (NRFHR) heart rate, meconium stained liquor and low APGAR values were present in 15, 20 and 10% cases respectively. Hypercoiling was associated with diabetes (10%), hypertension (5%), oligohydramnios (10%), polyhydramnios (5%), NRFHR (10%) and meconium stained liquor (5%). However, there was no statistical significance among the above mentioned parameters.
Ovarian teratomas in bimodal age groups- Case report
Authors: Rao Bharathi , Bhatia Shweta , Suresh Pooja K , Bhatt Anusha S 
Published: August 2021

Ovarian teratomas are the most common germ cell tumors and are classified as mature, immature and malignant.Mature cystic teratomas, also called dermoid cysts, are the most common germ cell tumour, accounting for upto 70% of benign ovarian masses in the reproductive years and 20% in postmenopausal women.Immature ovarian teratoma affects primarily younger patients and mature cystic teratomas seen in reproductive age groups. This case report provides a brief summary of the clinicopathological features of the ovarian teratomas such as, the immature teratoma which being a rare tumour was diagnosed in a 15 year old adolescent girl, managed surgically by laparotomy followed by chemotherapy, and the other case of a benign mature cystic teratoma in an elderly 52 year old postmenopausal woman, managed surgically although benign cystic teratomas are rare in the postmenopausal age group.
Psychological and Physiological Complications of Post-Burn Patients in Pakistan
Authors: Ali Meher B , Ali Mashal B 
Published: August 2021

Pakistan has a burn mortality rate of 6.5%, with a considerable percentage of survivors suffering from long-term complications due to lack of rehabilitation. The aim of this review is to outline the important physiological and psychological after-effects of burn injuries. Relevant articles were included by conducting a comprehensive search between 20th March and 25th May 2020. Psychological complications of burns include depression, post-traumatic stress disorder, anxiety, sleep disturbance, phobias, guilt, suicidal thoughts, and personality changes. Physiological complications include scarring, contractures, pain, muscle wasting, and hypothermia. Other complications include infections. The review revealed a scarcity of literature regarding the prevalence and impact of long-term complications in post-burn patients. Our findings include a lack of rehabilitative services and high rate of post-burn complications in Pakistan. Rehabilitation of burn patients should be a continuation of active treatment and should begin from the day of admission, to reduce the morbidity and improve the quality of life of burn patients.
Keywords: Burns; physiology; psychology; rehabilitation; quality of life.
Mortalidade em portadores de HIV/aids no Pará
Authors: Pontes Karolaine Galvão , Matsumura Erica Silva de Souza , Cunha Katiane da Costa 
Published: August 2021

Verificar o índice de mortalidade em portadores do vírus da imunodeficiência humana (HIV) e/ou aids no estado do Pará entre os anos de 2007 a 2017. Trata-se de um estudo descritivo, transversal e retrospectivo, por meio da base de dados DATASUS (departamento de informática do sistema único de saúde) na faixa etária de 20 a 59 anos. Como resultados temos, a região metropolitana I apresentou maior prevalência de óbitos, seguida de Carajás. A idade onde se concentrou maior mortalidade foi em adultos de 30 a 39 anos, além de que o estado civil mais comum foram os declarados solteiros. Em relação ao índice de escolaridade, a maioria se concentrou entre 4 a 7 anos de estudo, e no que concerne a cor/raça, a parda foi a mais comum. A respeito da região Metropolitana I apesar de ter quantitativo menor de municípios foi a com maior mortalidade devido a questão populacional, a discrepância entre homens e mulheres se deve ao fato de que eles não procuram centros de saúde com assiduidade, já o tempo de estudo foi relativamente curto devido a problemas escolares/reprovações. Portanto, o HIV ainda é um importante marcador de mortalidade no estado do Pará, e os homens ainda são maioria nesses casos.
Terapia gênica em doenças falciformes: Análise dos efeitos curativos nas beta-talassemias e nas anemias falciformes
Authors: Sarmento Ianaly Raiane Abrantes , Souza Maria Alciene Saraiva de , Abreu Dandara Dias Cavalcante , Gomes Maria Raphaella Ferreira 
Published: August 2021

OBJETIVO: relacionar as Doenças Falciformes com a terapia gênica, tendo em vista a possibilidade da correção genética dessas hemoglobinopatias hereditárias. MÉTODOS: o delineamento consistiu em uma revisão integrativa a partir de artigos publicados nas bases de dados PubMed, Lilacs, e da Biblioteca Virtual em Saúde (BVS), combinando os seguintes descritores: Genetic therapy AND Anemia, Sickle Cell e Beta-thalassemia AND Anemia, Sickle Cell. Após busca e aplicações dos critérios de inclusão e exclusão restaram assim oito artigos, os quais compõem esta revisão. RESULTADOS E DISCUSSÕES: a maioria dos artigos utilizados faziam uma abordagem geral sobre a terapia genética em pacientes beta-talassêmicos, comparando as características destes com as dos indivíduos falciformes, ressaltando as grandes chances de controle e até mesmo da cura destas através da inserção ou edição de genes como também transplante das células hematopoiéticas. Estudos atuais apostam em avanços científicos no ramo da biologia da manipulação para que haja uma modificação genética com transfusão de células em crianças pré-diagnosticadas com alguma hemoglobinopatia, impedindo assim que ocorram as manifestações clínicas da doença. CONSIDERAÇÕES FINAIS: sabendo-se do grande número de nascidos portando algum tipo de Doença Falciforme, a modificação genética do sangue do cordão umbilical e o desenvolvimento de células estaminais hematopoiéticas seria, portanto uma terapia ideal para a diminuição dos casos de recém-nascidos portadores de Anemia Falciforme ou de Beta-talassemia. Já nos casos já existentes, a abordagem terapêutica que mostra maior eficiência e facilidade de acesso seria àquela que combina o aumento do volume celular com a diminuição da hemoglobina intracelular.
A educação alimentar de nutricional como estratégia no tratamento e controle do diabetes mellitus tipo 2: Uma revisão sistemática.
Authors: Silva Samillys Valeska Bezerra de França , Ávila Rígila Taiane Cunha , Couto Lívia Viviane Guimarães do 
Published: August 2021

A Educação Alimentar e Nutricional é considerada como uma ferramenta imprescindível para o controle glicêmico em diabéticos tipo 2. O estudo objetivou avaliar se as intervenções de educação nutricional melhoram o controle glicêmico em portadores de Diabetes Mellitus tipo 2. Realizou-se a busca para seleção dos estudos nos bancos de dados: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Portal da Biblioteca Virtual em Saúde (BVS), US National Library of Medicine National Institutes of Health- (Pubmed), e Cochrane Library. Foram identificados 5.437 estudos nas bases, após a seleção foram elegidos 6 estudos para a revisão sistemática. As intervenções nutricionais melhoram significativamente o controle glicêmico em pacientes de meia idade com diabetes tipo 2. Cinco estudos mostram resultados positivos na melhora do controle glicêmico e um estudo não apresentou melhora significativa nos níveis glicêmicos comparado ao grupo controle. A partir desses resultados, a maioria dos estudos demonstrou que os programas de educação nutricional melhoram o nível de conhecimento nutricional e aumentam a adesão às práticas de alimentação saudável em grupos de diabéticos tipo 2 e melhoram significativamente o controle glicêmico.
Contact Dermatitis Knowledge Level in Batik Workers of Desa Batik, Tanjung Bumi, Bangkalan, Madura
Authors: Prakoeswa Cita Rosita Sigit , Rahmadewi Rahmadewi , Setyaningrum Trisniartami , Damayanti Damayanti , Mappamasing Hasnikmah , Anggraeni Sylvia , Umborowati Menul Ayu 
Published: August 2021

Background: Batik has been declared as a humanitarian heritage for oral and non-cultural culture. The increasing demand for batik may have a negative impact as the industry utilizes chemical agents. Hazardous chemical exposure to the skin in the batik industry may result in a high risk of occupational contact dermatitis. This study was conducted to find out the social determinants of health. Purpose: This study aims to assess the level of knowledge of the batik workers before and after health education about occupational contact dermatitis. Methods: This was an observational interview study, and the data were collected using questionnaires. This study involved 30 batik workers. We assessed the level of knowledge before and after the health education about occupational contact dermatitis. Result: There were 4 (13.3%) male participants and 26 (86.7%) female participants. The mean score of the pre-test was 66.98±10.10, and the post-test was 77.77±13.53 (p<0.05). Conclusion: The result showed a significant difference between batik workers' knowledge before and after health education about contact dermatitis.
Sistemik lupus eritematozusda prognostik nutrisyonel indeksin hastalık aktivitesi ile olan ilişkisinin araştırılması: Tek merkez deneyimi
Authors: BİLİCİ SALMAN Reyhan , HAZNEDAROĞLU Şeminur 
Published: August 2021

Amaç: Periferik kandaki serum albümin seviyesi ve lenfosit sayısı ile hesaplanan ve hastaların immün-beslenme durumu yansıtan prognostik nutrisyon indeks (PNI) ile Türkiye’deki SLE hastalarında hastalık aktivitesi (SLEDAI-2K) arasındaki ilişkiyi göstermeyi ve PNI’nın hastalık aktivitesinin bağımsız bir prediktörü olduğunu göstermeyi amaçladık.
Yöntem: PNI, 156 SLE hastasında aşağıdaki formüle göre hesaplandı: 10 x serum albümin değeri (g / dL) + 0.005 x periferik lenfosit sayısı (/ mm3). PNI ile laboratuvar değişkenleri arasındaki ilişkilerin analizinde Spearman korelasyon analizi kullanıldı. Laboratuvar ve klinik değişkenler ile SLE Hastalık Aktivite İndeksi-2000 (SLEDAI-2 K) arasındaki ilişkiyi göstermek için lojistik regresyon analizleri yapıldı.
Bulgular: 79’u hastalık aktivitesi yüksek (SLEDAI-2K>10)ve 77’si hastalık aktivitesi düşük toplam 156 SLE hastası çalışmaya alındı. Yüksek hastalık aktivitesine sahip SLE hastalarının medyan PNI'si, hastalık aktivitesi düşük olanlar ile kıyaslandığında daha düşük saptanmıştır (38'e karşı 42, p
Covid-19 Pandemisinin Çocuk Yoğun Bakım Ünitesi Yatışlarına Etkisi
Authors: EMEKSİZ Serhat , UYAR Emel , PERK Oktay , ÖZCAN Serhan 
Published: August 2021

Amaç: Bu çalışmada pandemi döneminde; sosyal izolasyon, alınan önlemler ve hastane protokollerinin üçüncü basamak pediatrik yoğun bakım pratiğine etkisini araştırmak amaçlanmıştır.
Gereç ve Yöntem: Çalışmamıza; 15 Mart 2020-1 Haziran 2020 tarihleri arasında çocuk yoğun bakım ünitemize kabul edilen çocuk hastalar dahil edildi. Hastaların demografik özellikleri, yatış tanıları, mekanik ventilatöre bağlanma oranları, mekanik ventilatörde kalış süreleri, ÇYBÜ ve hastane yatış süreleri, PRİSM III skorları ve mortalite durumları medikal dosya verilerinden retrospektif olarak kaydedildi. Elde edilen veriler pandemiden önceki yılın aynı dönemiyle (15 Mart 2019 – 1 Haziran 2019) karşılaştırıldı.
Bulgular: Pandemi döneminde ÇYBÜ’ne kabül edilen hasta sayısı 200’dü. Pandemi öncesi (2019) dönemde 379 hasta yatışı olmuştu. ÇYBÜ’ne kabül edilen hasta sayısında pandemi döneminde bir önceki yıla göre %47 oranında bir düşüş saptadık. Pandemi öncesi dönem ile pandemi dönemi; hastaların yoğun bakıma yatış tanıları açısından karşılaştırıldığında, solunum yolu hastalıkları (pnömoni, bronşiolit, astım vb.) ve post-op hasta yatışlarında azalma, diabetik ketoasidoz nedeni ile yatışlarda artış saptandı ve istatistiksel olarak anlamlı farklılık vardı. Ayrıca hastaların pandemi döneminde mekanik ventilatörde kalış süreleri, hastanede kalış süreleri ve yoğun bakımda kalış sürelerinde azalma saptadık ve bu durum istatistiksel olarak da anlamlıydı.
Sonuç: Sosyal mesafenin, maske kullanmanın ve hijyen kurallarına uyumun enfeksiyon bulaş riskini azalttığını ve bu durumun yoğun bakım yatış sayısında azalmaya neden olduğu tahmin etmekteyiz. Buradan yola çıkarak; sosyal mesafeye ve el hijyenine uyumu belki de hayatımızın bir parçası olarak kabul edip, bulaş riskinin yüksek olduğu kreş ve okullarda ileriki dönemlerde buna yönelik düzenlemelerin yapılması gerektiğini vurgulamak istiyoruz.
KARAKTERISTIK BIOSORBEN PELEPAH NIPAH (Nypa Fruticans) UNTUK PENURUNAN KADAR LOGAM BERAT AIR MERKURI (Hg)
Authors: Ikhsan Aulia Noor , Azmiati Yaya , Delvianti Ulfah , Syauqiah Isna 
Published: August 2021

Penelitian ini bertujuan untuk mengetahui karakteristik biosorben pelepah nipah dan menentukan kondisi optimum ukuran partikel dan waktu kontak dalam penurunan kadar merkuri. Proses maserasi menggunakan metanol dan diaktivasi menggunakan HCl. Hasil analisa FT-IR menunjukkan bahwa pada biosorben pelepah nipah memiliki kandungan selulosa yang ditunjukkan dengan gugus fungsi O-H, C-H dan C-O. Pada analisa SEM menunjukkan bahwa luas permukaan biosorben ukuran 100 mesh lebih besar dibandingan dengan luas permukaan 60 dan 80 mesh. Hasil pengujian AAS pada sampel pada ukuran 60 mesh dengan wantu kontak 30,60 dan 90 menit yaitu 99,99902 %, 99,99922 % dan 99,99942 %, pada ukuran 80 mesh dengan waktu kontak 30,60 dan 90 menit yaitu 99,99951 %, 99,99958 % dan 99,99966 %, pada ukuran 100 mesh dengan waktu kontak 30,60 dan 90 menit yaitu 99,99973 %, 99,99981 % dan 99,99989 %. Penyerapan kadar merkuri terbanyak terjadi pada biosorben ukuran 100 mesh dengan waktu kontak 90 menit yaitu 99,99989 %. Kata Kunci : Adsorpsi, biosorben, karakteristik, merkuri, pelepah nipah. This research attempts to know characteristic of nypa midrib biosorbent and determine optomization particle size and contact time in reduce level mercury. Maceration process using methanol and activation biosorbent is using HCl. The results of FTIR analysis shows that nypa midrib biosorbent contains cellulose indicated by the fungsional group O-H, C-H and C-O. SEM analysis is shows that the surface area biosorbent 100 mesh is bigger than surface area 60 and 80 mesh. The result of AAS for sample 60 mesh with contact time 30, 60 and 90 minute is 99,99902 %, 99,99922 % dan 99,99942 %, at 80 mesh with contact time 30,60 and 90 minute is 99,99951 %, 99,99958 % dan 99,99966 %, and at 100 mesh with contact time 30, 60 and 90 minute is 99,99973 %, 99,99981 % dan 99,99989 %. The highest absorption of mercury levels occurred in biosorbent 100 mesh with contact time 90 minute is 99,99989 %. Keywords: Adsorption, biosorbent, characteristic, mercury, nypa midrib.
KONTRIBUSI KEPUASAN MAHASISWA TERHADAP MOTIVASI BERPRESTASI MAHASISWA (Studi analisis deskriptif pada kelompok Belajar Barabai Kalimantan Selatan)
Authors: Aisyah Siti 
Published: August 2021

Penelitian ini bertujuan untuk mengungkapkan tentang: (1) tingkat kecenderungan kepuasan mahasiswa (2) Tingkat kecenderungan motivasi berprestasi mahasiswa serta, (3) hubungan antara kepuasan mahasiswa dengan motivasi berprestasi mahasiswa Universitan Terbuka Kelompok Belajar Barabai. Populasi penelitian ini berjumlah 60 orang mahasiswa Universitan Terbuka Kelompok Belajar Barabai. Karena jumlahnya yang tidak terlalu banyak maka semua populasi dijadikan sampel penelitian/sampel penuh. Data di kumpulkan dengan menggunakan koesioner. Pengujian hepotesis dilakukan dengan menggunakan teknik analisis uji korelasi pada taraf kepercayaan 0,95. Hasil analisis statistik deskriptif menunjukkan bahwa kepuasan mahasiswa dalam kategori tinggi, dan motivasi berprestasi mahasiswa tergolong dalam kategori tinggi. Berdasarkan hasil analisis korelasi produnc moment diperoleh r hitung =0,337 sedangkan harga r tabel pada n 60 = 0,250, karena harga r hitung > r tabel maka dapat dikatakan terdapat korelasi yang ;ositip dan signifikan antara kepuasan mahasiswa dengan motivasi berprestasi Universitas Terbuka Kelompok Belajar Barabai dengan peluang kesalahan 0,05. Penelitian ini diharapkan dapat memberikan gambaran sekaligus kontribusi kepada mahasiswa untuk mengetahui tingkat motivasi berprestasi, kepuasan mahasiswa. Di samping itu, penelitian ini juga dapat dijadikan masukan bagi pengelola Universitan Terbuka Kelompok Belajar Barabai dalam upaya menimngkatkan layanan terhadap mahasiswa di daerahnya.
THE EFFECT OF REAR SPROCKET SIZE VARIATION ON POWER AND TORQUE ON YAMAHA VIXION MOTORCYCLES IN 2015
Authors: Saputro Yoyo , Prasetyo Imam , Nadhief Muhammad Thomi 
Published: August 2021

Sepeda motor dilengkapi dengan sistem pemindahan tenaga yang mampu menjembatani antara output mesin (daya dan torsi mesin) dengan tuntutan kondisi jalan, sprocket adalah bagian terakhir dari sistem pemindah tenaga, karena sprocket merupakan bagian yang menyalurkan tenaga mesin motor ke roda belakang melalui rantai. Peneliti terdahulu mengganti ukuran sprocket dengan mata sprocket lebih besar atau lebih kecil 2 mata dari sprocket standar sedangkan dalam penelitian ini mengganti sprocket belakang dengan jumlah mata besar dan lebih kecil 4 mata dari sprocket standar. Tujuan penelitian ini untuk mengetahui pengaruh variasi ukuran sprocket belakang terhadap daya dan torsi pada motor vixion tahun 2015. Penelitian ini menggunakan metode pengambilan data dari uji daynotest menggunakan alat dynamometer. Hasil pengujiannya yaitu pengaruh variasi ukuran sprocket 43T, 39T, dan 47T menghasilkan peningkatan daya dan torsi paling optimal pada sprocket ukuran 47T dengan data daya maksimum sebesar 16.1 HP, dan torsi diperoleh data dengan sprocket ukuran 47T menghasilkan torsi maksimum sebesar 14.42 Nm hal ini di sebabkan karena jumlah mata sprocket yang banyak dan jarak antara sprocket depan dengan sprocket belakang lebih pendek.