bluuebunny/crossref_metadata_2025_split huggingface dataset:
repercussões das condições crônicas de saúde na família
Authors: Simon Bruna Sodré , Garcia Raquel Pötter 
Published: August 2021

A transição demográfica e epidemiológica no Brasil tem demonstrado uma redução no quantitativo de condições agudas de saúde e elevação nas condições crônicas. Essas, em sua maioria, são imprevisíveis, apresentam progressão lenta, multicausalidade e potencial para perda funcional com o decorrer do tempo. Nossas vivências e experiências, enquanto enfermeiras, docentes e pesquisadoras, corroboram para o entendimento de que as condições crônicas de saúde têm repercussões na família. Essa perspectiva vai ao encontro da compreensão de família como um sistema, formado por subsistemas individuais, correspondentes aos seus membros e, por um suprassistema, representado pelas relações de amizade, de trabalho e demais componentes da sociedade com os quais interagem.
Open field mirror test as a tool for the assessment of visual functions in rats with streptozotocin-induced diabetes
Authors: Sadikan Muhammad Zulfiqah , Abdul Nasir Nurul Alimah , Iezhitsa Igor , Agarwal Renu 
Published: August 2021

To evaluate the use of mirror test in an open field arena as a visual function assessment tool in a rodent model of diabetes. Male Sprague-Dawley rats were divided into diabetic rats, that received intraperitoneal streptozotocin (55 mg/kg body weight) for induction of diabetes, and control rats that similarly received citrate buffer. Rats with a blood glucose level of more than 20 mmol/L were considered diabetic. Blood glucose was monitored weekly throughout the experimental period. General behavioural assessment of the rats was done at week 12 post-induction using open field arena, followed by visual-behavioural assessment with mirror and reversed mirror added in the arena. Subsequently, rats were euthanised and subjected to haematoxylin and eosin staining (H&E) staining to assess changes in retinal morphology. In the open field test, diabetic rats showed a lesser number of zone crossings (3.73-fold, p<0.001), total distance travelled (2.02-fold, p<0.001), number of rearing episodes (2.22-fold, p<0.001) and number of grooming episodes (4.33-fold, p<0.01) but a greater number of freezing episodes (2.47-fold, p<0.001) and number of the faecal pellet (4.17-fold, p<0.01) compared to control rats. Control rats spent more time with higher zone entries toward mirrored than non-mirrored and reversed mirror zones (p<0.05 and p<0.01 respectively), whereas diabetic rats showed no preference for zones. Normal rats also showed higher freezing episodes within the mirrored zone compared to diabetic rats (2.00-fold, p<0.05). The retinal morphometry showed significant thinning of various retinal layers in the diabetic group compared to control rats. Visual behavioural activities of diabetic rats in an open field arena with the presence of a mirror could detect the presence of visual loss. Changes in visual functions positively correlated with changes in retinal morphology. Therefore, an open field mirror test could be used as an alternative for assessing visual function in the rodent model of diabetes.
Possibilities of prognosis and improvement of treatment results in children with congenital malformations of the gastrointestinal tract
Authors: Budarova K. V. , Shmakov A. N. , Chekanov M. N. , Vereshchagin E. I. , Peshkova I. V. , Polyakevich A. S. 
Published: September 2021

The category of newborns with congenital malformations is considered the most difficult to treat. The influence of “stress”factors on the body in a short period of time triggers a pathogenetically determined chain reaction that leads to the development of multiple organ failure syndrome. The forecasting methodology determines the timeliness and directions of intensive care to approach and achieve positive results in this group of patients.The aim of the study: is to show the diagnostic and practical value of metabolic markers and functional indicators of homeokinesis in newborns with congenital malformations of the gastrointestinal tract.Materials and methods. An observational study of 81 patients in the neonatal period. The prognostic assessment of functional parameters and biochemical markers was performed by ROC analysis.Results. In newborns with malformations of the gastrointestinal tract, the course of the pre-and early postoperative period is associated with cardiopulmonary maladaptation, which requires the protection of vital functions. By the end of the first week, priority is given to therapy aimed at restoring the motility of the gastrointestinal tract. The prognostic value of the adverse outcome was determined: stress index greater than 3503 Sp = 98.36% (95%CI 86.3–99.2) and Se = 99.2% (95%CI 87.3–100), lactatemia level greater than 3.3 mmol/L Sp = 73.7% (95% CI 59.6–84.7) and Se = 93.6% (95% CI 78.9–100). The control of the infectious process and the selection of antibacterial therapy is important, since the risks of developing septic shock are high. Prolonged epidural analgesia is the optimal method of analgesia and is indicated in suspected cases of failure to achieve 75% of the volume of enteral nutrition by the week of the postoperative period Sp 85.42% (95%CI 48.2–97.7), Se 46.8% (95% CI 62.0–84.2).Conclusions. Prognostic models allow predicting the outcome of critical conditions and timely adjusting the volume of therapy.
Sturge-Weber syndrome: Clinico-neuroradiological features and treatment profile
Authors: Chatterjee Anirban , Sinha   Malay Kumar 
Published: September 2021

Introduction: Sturge Weber syndrome (SWS) is a rare, nonhereditary genetic disorder. SWS belongs to a diverse group of Neurocutaneous disorders. A somatic mutation in the early development of cells in SWS patients causes the formation of a congenital capillary vascular malformation. SWS is characterized by nevus flammeus on the face (also called Port-Wine Birthmark), brain (leptomeningeal angioma), and eyes (glaucoma).
Methods and Materials: We present three patients diagnosed with Sturge Weber syndrome who attended a teaching hospital between 2013 to 2016. The clinical, neuroradiological features and treatment of SWS patients were reviewed retrospectively from medical records.
Results: Two males and females with SWS were reviewed. The facial nevus flammeus was unilateral in one patient and bilateral in two patients. The extensive nevus flammeus including the face, trunk, and upper limb was found in one patient. Epilepsy, neurodevelopmental delay, and intellectual disability were the most common presentation in the series. Episodic hemiparesis was manifested in one patient. Levetiracetam and oxcarbazepine, either single or combined, were used in every SWS patient (n=3). Six months seizure-free was obtained in a patient with SWS with combined anticonvulsant therapy.
Conclusion: Drug-refractory and early-age epilepsy is associated with lower intelligence level that consequently affects poor social skill and quality of life in the patients with SWS. Sudden or gradual loss of vision is also a threat for SWS patients. Diagnosis at birth or during early age, multidisciplinary intervention, and follow-up is a must to improve absolute outcomes in the patients with SWS.
Penggunaan Metode AHP Pengangkatan Karyawan Tetap Pada PT Prima Top Boga
Authors: Kodir Saepul , Nurmalasari Nurmalasari , Yoraeni Ani 
Published: September 2021

Karyawan merupakan aset penting bagi perusahaan. Tanpa karyawan. Untuk itu, PT Prima Top Boga haruslah tidak salah dalam merekrut karyawannya. Permasalahan yang terjadi pada PT Prima Top Boga yaitu masih belum optimalnya dalam proses perekrutan karyawan tetap dan sering terjadi kesalahan dalam memilih karyawan terbaik untuk direkrut menjadi karyawan tetap. Dalam hal ini penulis menggunakan metode Analytical Hierarchy Process dengan enam kriteria didalamnya sebagai tolak ukur dalam penelitian serta empat alternatif. Pada penelitian ini, penulis membagikan kuesioner kepada tiga responden yang berkompeten pada bidang terkait, kemudian data tersebut diolah dengan menggunakan aplikasi microsoft excel dan aplikasi expert choice. Maka yang berhasil menjadi karyawan tetap adalah Karta Atmaja dengan preferensi sebanyak 0.344. atau 34%.
PERINATAL OUTCOME OF VAGINAL BREECH DELIVERY VERSUS CAESAREAN BREECH DELIVERY
Authors: Malik Rupal , Gupta Ritu 
Published: September 2021

Background: The aim to find out any differences in outcome between vaginal breech delivery and cesarean breech delivery in our setup
Methods: Data were collected from record book of Department of Gynecology and obstetrics. Data of 100 patients were analysed among which 36 underwent vaginal delivery for breech and 64 underwent cesarean breech delivery
Results: Binary logistic regression was used to compare outcome among different groups. In our study only 5.56% of newborn delivered by vaginal route were admitted to NCU vs. 12.50% in cesarean group which was significant (odds ratio=0.07, P=0.01)
Conclusion:
Keywords: LSCS, Breech, NICU
RAILWAY STRUCTURES PERFORMANCE DUE TO FREIGHT INTERMODAL SERVICE AT BOJONEGORO – KALITIDU ROUTE
Authors: Nugroho Utomo  
Published: September 2021

Goods movement using container are quite efficiently assessed because it can carry a great amount of goods fit to container capacity. Freight transportations is a primary component of all supply-chain and logistics systems, but in contrary using a truck as its transportation means causing many problems such as air and noise pollutions, traffic congestions, road accidents and road damage. Depart from this facts, so government is looking for another means of freight transporter which more efficient with a bigger load capacity advantages. This options goes to train as a solutions of intermodal freight transportations lack. In order to supporting intermodal freight transportations, right now double track of railway is available for Jakarta – Surabaya route (Northern line route). By now, noted that freight transportation with double track railway frequency is potentially increase to 15 trip per days with capacity 500 TEU (Twenty feet Equivalent Units) per days and fuel consumptions (with truck) can be thrifted into 115 kl per days also reducing carbon monoxide emission amounts 350 tons per days. According with an official statements from Directorate General of Railways, Ministry of Transportations, explained that Jakarta – Bojonegoro route on double track railway is fully operated so this paper is conducted to determining feasibility of railway structure performance due to freight intermodal transportations at Bojonegoro – Kalitidu route. Railway structure performance feasibility is observed from loading distributions, rail strength, rail sleeper strength, and railway subgrade endurance to planned freight trains. As a result of this research obtained that tension force that occurred on rail is 830,10 kg/cm2 < permitted tension on rail (first class rail) 1325 kg/cm2. So, tension force that occurred on rail is safe. Moment force that occurred on rail bottom is 14521,25 kg.cm < permitted moment force (150.000 kg.cm) Moment force that occurred in the middle of rail sleeper is 58993,978 kg.cm < permitted moment force (93000 kg.cm). Tension force that occurred on above railway subgrade (σ2) is 4,17 kg/cm2 < qu (29,671 kg/cm2). It means that railway subgrade is capable to supporting load of freight transportation operations along Bojonegoro – Kalitidu route.
HUBUNGAN FUSSY EATING DAN EARLY CHILDHOOD CARIES
Authors: Praziandite Muthiara 
Published: August 2021

Latar Belakang: Fussy Eating merupakan gangguan makan yang umum terjadi pada anak tetapi memilki dampak buruk bagi kesehatan, termasuk kesehatan gigi dan mulut. Early Childhood Caries (ECC) adalah penyakit jaringan keras gigi yang paling banyak terjadi pada anak dengan prevalensi mencapai 90% (Riskesdas, 2018) . Tujuan: peneltian ini bertujuan untuk mengetahui hubungan Fussy Eating dan Early Chidhhood Caries (ECC) pada anak. Metode: penelitian ini merupakan penelitian observasional dengan desain cross sectional. Pengambilan sampel dilakukan purposive sampling dengan jumlah sampel sebanyak 165 orang berusia 3-5 tahun beserta ibunya. Children Eating Behaviour Qutionnaire (CEBQ) subskala Food Fussiness digunakan untuk mengukur Fussy Eating pada anak. ECC diukur dengan index def-t. Analisis data menggunakan uji chi-square. Hasil: Prevalensi anak dengan Fussy Eating adalah 50,9%. Terdapat hubungan bermakna antara Fussy Eating dan kejadian ECC pada anak (p-value = 0,010; OR = 2,380; 95% CI 1,273-4,450). Kesimpulan: Fussy Eating berkontribuasi dalam kejadian ECC.
Corrigendum
Authors: Transportation Engineering Periodica Polytechnica 
Published: September 2021

László Lindenmaier, István Ferenc Lövétei, Gábor Lukács, Szilárd Aradi "Infrastructure Modeling and Optimization to Solve Real-time Railway Traffic Management Problems", 49(3), pp. 270–282, 2021. (in this issue)https://doi.org/10.3311/PPtr.18582When the above article was first published online some symbols in the text on pages 274–276, Table 7 on page 277, furthermore the subscript of the symbol bs in Eqs. (10), (11) and in the text on page 277 were incorrect. This has now been corrected in the online version. The correct version of some symbols in the text on pages 274–276, Table 7 on page 277, furthermore the subscript of the symbol bs in Eqs. (10), (11) and in the text on page 277 were published in this paper.
Clinical Presentation of Patients with Thyroid Cancer in Tertiary Level Hospitals
Authors: Hossain AKM Farhad , Wahab Md Abdul , Khatun Sayada Fatema , Zafreen Farzana 
Published: September 2021

Introduction: Thyroid malignancy is the most common endocrine malignancy seen in clinical practice. Incidence of thyroid cancer varies worldwide from 0.5 to 10 per 1,00,000 populations annually. Exact incidence of thyroid cancer in Bangladesh is not known.
Aim: To find out the clinical presentation of patient with thyroid cancer and identify the association between socio- demographic features and clinical presentation.
Methods: This cross sectional study was conducted purposively among 246 thyroid cancer patients in two tertiary hospitals of Dhaka city from 01 July 2018 to 30 June 2019. Data were collected by face to face interview using semi-structured questionnaire and checklist and were were analyzed by Statistical Package of Social Science v23.
Results: Study revealed that mean±SD age of the respondent was 37.9±12.20years (range 14-70 years). Majority 74.4% of respondents was female, married 72%, housewife 61.4%, primary education 69.0% and mean±SD monthly family income was BDT 17,681±10,602. Approximately 82.9% of patients had papillary cancer and 17.1% had follicular cancer. Various clinical presentations included, neck swelling 91.5%, swollen lymph node 41.9%, pain 36.6%, dysphonia 57.3% and dysphagia 35.4%. Study revealed the significant association of clinical presentation with gender, education and occupation of the respondents (p<0.05).
Conclusion: Incidence of thyroid cancer has increased worldwide specially in female patients. As thyroid cancer is a growing public health problem in Bangladesh, proper screening and early diagnostic facilities at all level should be available to measure its actual burden in the country.
JAFMC Bangladesh. Vol 15, No 1 (June) 2020: 22-25
Linfoma T intestinal epiteliotrópico monomórfico
Authors: Vintimilla Cazorla María Paz , Yoncón Romero Ricardo , Benites Ordinola Carlos , Nieto Orellana Jorge , Ochoa Bastidas Anthony , Huamán Garaicoa Fuad 
Published: September 2021

Introducción: El linfoma de células T intestinal epiteliotrópico monomórfico es una neoplasia derivada de linfocitos intraepiteliales. La etiología es desconocida, pero se ha asociado a enfermedad celíaca o a síndrome de malabsorción, aunque en la actualidad se considera un linfoma esporádico. La histopatología se caracteriza por linfocitos de tamaño intermedio a pequeño, con mínimo pleomorfismo, que generalmente expresan CD8 y CD56.
Reporte de caso: Mujer de 60 años con un cuadro de dispepsia de larga evolución, ingresada por dolor abdominal agudo, diarrea, nausea, vómito bilioso y pérdida de peso. En los estudios se determinó anemia microcítica hipocrómica y desequilibrio hidroelectrolítico. Se evidenció por tomografía de abdomen una lesión nodular esplénica y engrosamiento concéntrico segmentario de yeyuno e íleon distal asociado a la presencia de líquido libre en cavidad abdominal.
Evolución: Se realizó una laparotomía exploratoria con resección de yeyuno-transverso anastomosis latero-lateral, en patología se deteminó la presencia de 3 tumores: a nivel de yeyuno de 16x8.5x6 cm, en el íleon distal de 13x6.5x3 cm y en el ciego de 5x4x2cm con histología de linfoma no Hodgkin T de alto grado, intestinal primario, de tipo monomórfico epiteliotrópico (MEITL). Fue dada de alta en mejores condiciones diez días después. Dos semanas luego del alta desarrollo sepsis de foco urinario, deshidratación por síndrome de intestino corto, hiperamonemia y neumonía de focos múltiples con derrame pleural bilateral. Falleció al sexto día de hospitalización.
Conclusiones: En conclusión, el MEITL es una neoplasia agresiva primaria intestinal de reciente identificación y pobre pronóstico. No se conocen en su totalidad los mecanismos moleculares y genéticos asociados a esta entidad. El caso presentado demostró un curso clínico similar al reportado en la literatura.
Incidencia de trombosis venosa profunda en pacientes diagnosticados con neoplasias útero- ováricas
Authors: Arguello Santacruz Mario Andres , Loor Holguín Jonathan Lenin , Venegas Arteaga Carlos Alfredo 
Published: September 2021

Introducción: El trombo embolismo venoso (TEV), una complicación frecuente en pacientes con cáncer ginecológico. El objetivo del estudio fue determinar la incidencia de TEV profunda en pacientes diagnosticados con neoplasias útero ováricas en un centro de referencia oncológica en Guayaquil-Ecuador en el año 2019 (enero-diciembre).
Metodología: El presente estudio observacional, de fuente retrospectiva se realizó en el servicio de estadística del Instituto Oncológico Nacional “Dr. Juan Tanca Marengo” de la Sociedad de Lucha contra el Cáncer-SOLCA, Guayaquil Ecuador. El cálculo del tamaño muestral fue probabilístico de 237 pacientes. Se incluyeron casos de pacientes con neoplasias útero ováricas y endometriales. Las variables fueron edad, localización de la neoplasia, incidencia de TEV en base a evidencia Ultrasonográfica de TEV, criterios Wels, dímero D. Se utilizó estadística descriptiva. Los porcentajes se presentan con intervalo de confianza.
Resultados: Se incluyeron 237 pacientes, el grupo etario más frecuente de 40 a 59 años con el 46.4%, seguido de 60 y más años con el 34.6%; el 88.6% de los casos tuvieron cáncer de útero (cérvix – endometrio) y el 11.4% con cáncer de ovario. Por la clasificación de Wells, el 92% presentó riesgo moderado de TVP y 8% riesgo alto. La incidencia de trombosis venosa profunda en pacientes con cáncer útero – ovario fue del 6.75% (IC 6.54-6.96%). La incidencia fue estadísticamente más prevalente (P=0.01) en el grupo de mujeres con Ca de Útero que en el grupo de Ca de ovario.
Conclusión: Las neoplasias útero ováricas tienen alta incidencia de trombosis venosa profunda.
Soteriological Studies About The Concept Of Choice God According To Romans 9:6-16
Authors: Prasetyo Widi s , Nababan Fernando , Purwanto Ani Teguh , Wibowo Daniel Ari 
Published: August 2021

God acts to choose a person or group and within a larger community, for a purpose or future of His own choosing. The main OT word for this word is bak-har (bak-har), which means to choose someone or something carefully, after carefully considering other possibilities. This word includes the mind, is very fond of the chosen thing, and sometimes receives pleasure from it. In the LXX and the NT the verb which corresponds to ba-khar is eklegomai. In ancient Greek this language was usually used in an active sense, and the biblical writers used it in a form meaning to choose for himself. (Hareomai) Haireomai, used of God's election in 2 Thess 2:13, and in Deut. 26:18 LXX, with the same meaning.
The Hebrew verb (yada) (yada), meaning to know which is used for various ways of knowing, at least in the mind, containing and expressing love such as sexual relations, or confession on the part of one who believes in God is used in Gen. 18:19; Hos 13:5 concerning the election of God means knowing God in love. Likewise, the Greek word proginosko meaning “to know beforehand” is translated “He chose” in Romans 8:29.Election is a fully sovereign act of God; Allah is in no way obligated to choose anyone because everyone has lost his position before Allah. Even after Christ's death, God was still under no obligation to carry out salvation. Except that He had to keep the agreement He had made with Christ regarding the salvation of mankind. So, God's election is a fully sovereign act because there is no coercion from anyone.
Perilaku Pencegahan Stunting pada Ibu Hamil
Authors: Nurfatimah Nurfatimah , Anakoda Priska , Ramadhan Kadar , Entoh Christina , Sitorus Sony Bernike Magdalena , Longgupa Lisda Widianti 
Published: September 2021

Pencegahan stunting mulai dari awal kehamilan harus dilakukan agar dapat menurunkan kejadian stunting pada anak. Kejadian stunting dapat terjadi pada masa kehamilan dikarenakan asupan gizi yang kurang saat hamil, pola makan yang tidak sesuai, serta kualitas makanan yang rendah sehingga mengakibatkan terhambatnya pertumbuhan. Tujuan penelitian untuk mengetahui gambaran perilaku ibu hamil dalam mencegah stunting pada balita di wilayah kerja Puskesmas Mapane. Desain Penelitian ini cross-sectional. Populasi penelitian adalah ibu hamil trimester II yang ada di wilayah kerja Puskesmas Mapane, berjumlah 49 orang. Teknik sampling yang digunakan adalah total sampling. Hasil Penelitian menunjukan bahwa 53.1% responden yang memiliki perilaku yang baik dalam pencegahan stunting. Hasil uji bivariat menunjukan umur >35 tahun (p=0,026), pendidikan perguruan tinggi (p<0,001), ibu bekerja (p<0,001), dan Multigravida (p=0,036) berhubungan dengan perilaku baik dalam pencegahan . Kesimpulan dari penelitian ini adalah perilaku ibu hamil yang baik dalam pencegahan stunting berada pada usia >35 tahun, pada tingkat pendidikan perguruan tinggi, pada ibu yang bekerja dan multigravida.
Novel Molecule Nell-1 Promotes the Angiogenic Differentiation of Dental Pulp Stem Cells
Authors: Li Mengyue , Wang Qiang , Han Qi , Wu Jiameng , Zhu Hongfan , Fang Yixuan , Bi Xiuting , Chen Yue , Yao Chao , Wang Xiaoying 
Published: August 2021

IntroductionThis work aimed to reveal the crucial role of Nell-1 in the angiogenic differentiation of human dental pulp stem cells (DPSCs) alone or co-cultured with human umbilical vein endothelial cell (HUVECs) in vitro and whether this molecule is involved in the pulp exposure model in vivo.MethodsImmunofluorescence was conducted to ascertain the location of Nell-1 on DPSCs, HUVECs, and normal rat dental tissues. RT-PCR, Western blot, and ELISA were performed to observe the expression levels of angiogenic markers and determine the angiogenic differentiation of Nell-1 on DPSCs alone or co-cultured with HUVECs, as well as in vitro tube formation assay. Blood vessel number for all groups was observed and compared using immunohistochemistry by establishing a rat pulp exposure model.ResultsNell-1 is highly expressed in the nucleus of DPSCs and HUVECs and is co-expressed with angiogenic markers in normal rat pulp tissues. Hence, Nell-1 can promote the angiogenic marker expression in DPSCs alone and co-cultured with other cells and can enhance angiogenesis in vitro as well as in the pulp exposure model.ConclusionNell-1 may play a positive role in the angiogenic differentiation of DPSCs.