bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contribution of soil compositions, harvested times and varieties on chemical fingerprint of Italian and Turkish citrus cultivars
Authors: Mottese Antonio Francesco , Sabatino Giuseppe , Di Bella Marcella , Fede Maria Rita , Parisi Francesco , Marcianò Giuseppe , Tripodo Alessandro , Italiano Francesco , Dugo Giacomo , Caridi Francesco 
Published: March 2021

SummaryThis paper aims to define the stability over the time of chemical elemental patterns in some citrus varieties of PGI (Protected Geographical Indication) and not PGI Interdonato and Lunario cultivars coming from Italy and Turkey and to set up a range of markers useful to trace their geographical origin. During the 2015–2017 growing seasons, all fruits were collected and subjected to Inductively Coupled Mass spectrometry (ICP‐MS) analysis, in order to determine the multielemental chemical profiles. The chemical variability was calculated for each element by Multi‐way analysis of variance. The results highlighted how the measured Cr, Ni, Al, K, Fe and Zn levels mainly depend on the soil composition and the fingerprint allow to trace the geographical origins. Moreover, the stepwise linear discriminant analysis (SLDA) has allowed to correctly classify the 100% of lemon pulps provenances, based on Ni, Al, K, Ca and Na contents. Finally, our study demonstrates the role played by harvest years, variety and soils composition whose interaction contributed to define the chemical fingerprints.
Risk of symptomatic COVID‐19 due to aircraft transmission: a retrospective cohort study of contact‐traced flights during England’s containment phase
Authors: Blomquist Paula Bianca , Bolt Hikaru , Packer Simon , Schaefer Ulf , Platt Steven , Dabrera Gavin , Gobin Maya , Oliver Isabel 
Published: March 2021

AbstractBackgroundKnowledge gaps remain regarding SARS‐CoV‐2 transmission on flights. We conducted a retrospective cohort study to estimate risk of acquiring symptomatic SARS‐CoV‐2 on aircraft, to inform contact tracing and infection control efforts.MethodsWe identified co‐passengers of infectious passengers on 18 England‐bound flights from European cities up to 12/03/2020, using manifests received for contact tracing. Infectious passengers were laboratory‐confirmed cases with symptom onset from 7 days before to 2 days after the flight. Possible aircraft‐acquired cases were laboratory‐confirmed with onset 3‐14 days post‐flight with no known non‐flight exposure. Manifests was merged with the national case management dataset (identifying cases, onset dates, contact tracing status) and the national COVID‐19 linelist. Contact tracing notes were reviewed to identify non‐flight exposures. We calculated attack rates (ARs) among all co‐passengers and within subgroups, including by distance from infectious cases and number of infectious cases on‐board.ResultsThere were 55 infectious passengers and 2313 co‐passengers, including 2221 flight‐only contacts. Five possible aircraft‐acquired cases were identified; ARs of 0.2% (95%CI 0.1‐0.5) among all flight‐only contacts and 3.8% (95%CI 1.3‐10.6) among contact‐traced flight‐only contacts sat within a two‐seat radius. The AR among 92 co‐travellers with known non‐flight exposure to infectious cases was 13.0% (95%CI 7.6%‐21.4%). There were insufficient numbers to assess differences between subgroups.ConclusionWe conclude that risk of symptomatic COVID‐19 due to transmission on short to medium‐haul flights is low, and recommend prioritising contact‐tracing of close contacts and co‐travellers where resources are limited. Further research on risk on aircraft is encouraged.
Gynaecological cancers and their cell lines
Authors: Skok Kristijan , Gradišnik Lidija , Maver Uroš , Kozar Nejc , Sobočan Monika , Takač Iztok , Arko Darja , Kavalar Rajko 
Published: March 2021

AbstractCell lines are widely used for various research purposes including cancer and drug research. Recently, there have been studies that pointed to discrepancies in the literature and usage of cell lines. That is why we have prepared a comprehensive overview of the most common gynaecological cancer cell lines, their literature, a list of currently available cell lines, and new findings compared with the original studies. A literature review was conducted via MEDLINE, PubMed and ScienceDirect for reviews in the last 5 years to identify research and other studies related to gynaecological cancer cell lines. We present an overview of the current literature with reference to the original studies and pointed to certain inconsistencies in the literature. The adherence to culturing rulesets and the international guidelines helps in minimizing replication failure between institutions. Evidence from the latest research suggests that despite certain drawbacks, variations of cancer cell lines can also be useful in regard to a more diverse genomic landscape.
Salinity, freshwater and agricultural water preferences of glass eels of the Japanese eel Anguilla japonica collected in southern Japan
Authors: Kumai Yusuke , Kuroki Mari 
Published: March 2021

AbstractWater‐choice trial experiments revealed that Anguilla japonica glass eels collected in southern Japan possess strong preferences for fresh water and agricultural water. Their locomotor activity and preference for fresh water were higher and stronger, respectively, in this study when compared to previous studies conducted at lower temperatures. These results suggest that their locomotor activity and preference for fresh water is influenced by water temperature. The attraction to agricultural water indicates their upstream migration and habitat selection could be influenced by agricultural water.
Understanding Differential Effectiveness of Behavioral Parent Training from a Family Systems Perspective: Families Are Greater than “Some of Their Parts”
Authors: Weeland Joyce , Helmerhorst Katrien O. W. , Lucassen Nicole 
Published: March 2021

AbstractBehavioral parent training (BPT) is a theory‐driven, evidence‐based, and widely used intervention strategy for preventing and decreasing children's disruptive behavior problems, indirectly via improved parenting behavior. However, not all families benefit equally from BPT. To date, our knowledge of who benefits (and who does not) and our understanding of why some families benefit more than others is limited. An important challenge for research and practice is finding ways to tailor interventions to the needs of an individual family and increase their effectiveness. We put forwardfamily systems theoryas a tool to gain more insight into which families (do not) benefit from BPT and why. We synthesize the theoretical foundations and empirical support for the putative mechanisms through which the functioning of family systems may explain BPT effectiveness and propose ways in which family systems theory can help strengthen the design, implementation, and evaluation of BPT programs.
Does negative contact undermine attempts to improve intergroup relations? Deepening the understanding of negative contact and its consequences for intergroup contact research and interventions
Authors: Schäfer Sarina J. , Kauff Mathias , Prati Francesca , Kros Mathijs , Lang Timothy , Christ Oliver 
Published: March 2021

AbstractIntergroup contact is an established pathway to improve intergroup relations. Research has long focused on mainly positive intergroup contact and its capability to improve intergroup relations. Yet, if members of different groups meet, they will not only make positive, but possibly also negative intergroup contact experiences. Recent research considering both positive as well as negative intergroup contact has raised concerns about potentially stronger effects of negative compared to positive contact. These new insights and the increasing awareness of potentially detrimental effects of contact could lead to doubts about whether it is always sensible to bring individuals from different groups together. Our article first updates the latest review on joint effects of positive and negative intergroup contact. We find that there is no clear tendency for either positive or negative intergroup contact to yield stronger effects on intergroup relations, and we portray factors that might influence these effects. Such factors—for example an individual's prior experiences—could play a crucial role in defining the relevance of negative contact in everyday settings. We continue by answering calls to increase a more qualitative understanding of what kinds of experiences are seen to be intergroup contact, and where intergroup contact in everyday life is experienced from a lay understanding, with new qualitative data from British White and British Asian individuals. Our results demonstrate that positive as well as negative contact is often rather casual and happens in public spaces and at work. Interventions explicitly addressing these spaces may help to reach more people. We also demonstrate that positive contact is much more frequent than negative contact. This finding is confirmed in the third section, which reviews the relative frequency of positive and negative intergroup contact. Last but not least, we discuss the implications of our review for practitioners and researchers alike.
Influence of oral movement, particle size, and zeta potential on astringency of whey protein
Authors: Carter Brandon G. , Drake MaryAnne 
Published: March 2021

AbstractAstringency is an important characteristic in whey protein products that leads to lower consumer liking, improvements in astringency may improve consumer acceptance of high protein products. The contributions of oral movement, particle size, and zeta potential on the perception of whey protein astringency were investigated. Trained panelists documented the astringency of 10% (w/w) whey protein isolate (WPI, >90% protein) solutions at pH 3.4 or 7.0 with or without oral movements. In a second experiment, 67 commercial WPI and whey protein concentrate 80% protein (WPC80) were evaluated for particle size and zeta potential at neutral pH, and of these, 21 were selected for further evaluation of astringency. Acidification of WPI increased astringency, but astringency was also documented in a neutral pH range (pH 6.0–7.0). Oral movements increased the perception of astringency (p < 0.05), suggesting that part of the astringent sensation was due to the interaction of whey proteins with receptors on oral tissues and oral movement further increasing astringency perception, possibly by friction of delubricated oral surfaces. Commercial WPI and WPC80 varied widely in particle size, zeta potential, and astringency. Astringency of WPI solutions were correlated with zeta potential (p < 0.05, r = −.81). WPC80 were astringent, but astringency of WPC 80 was not correlated with particle size or zeta potential (p > 0.05, r = .14, .40). These results provide information on the mechanism of whey protein astringency perception, which may facilitate the development of whey protein products with decreased astringency.Practical ApplicationsAstringency of whey proteins is complex and a result of multiple mechanisms. This study established that oral movements and zeta potential are linked to the astringency of whey protein. These results further explain the mechanisms of astringency and may help to identify possible methodologies to reduce astringency in whey protein ingredient applications.
Social Representations Theory and young Africans' creative narratives about human immunodeficiency virus/acquired immune deficiency syndrome, 1997–2014
Authors: Winskell Kate 
Published: March 2021

AbstractResearch on social representations (SRs) has often focused more on categorical than narrative‐based representations. However, narratives are considered to play a key role in the organization of SRs. This article describes an empirical study of some 2000 creative narratives about human immunodeficiency virus written by young Africans from five countries between 1997 and 2014 and examines the theoretical, methodological and applied relevance of Social Representations Theory (SRT) for this study and the implications of the study for the intersection between narrative and SRT. The study is unusual within the SR paradigm: it is temporal and cross‐national; addresses a subject whose science has evolved over time; and usescreativenarratives as its data source. A narrative perspective foregrounds holistic understandings of SRs as systems of thought. Creative narratives fit well within an SR framework. Our triangulating methodologies foreground categorical or narrative dimensions depending on the objectives of specific sub‐studies. Central Core Theory provides a framework to articulate stability and change within narrative representations. In creative narrative, objectification also happens at the level of plot and characters, such that dominant cultural narratives can be viewed as a form of hegemonic SR. We link with health communication and embrace more critical streams within SR research.
Ubiquitin‐specific protease 7 as a potential therapeutic target in dogs with hematopoietic malignancies
Authors: Pawlak Aleksandra , Bajzert Joanna , Bugiel Katarzyna , Hernández Suárez Beatriz , Kutkowska Justyna , Rapak Andrzej , Hildebrand Wojciech , Obmińska‐Mrukowicz Bożena , Freire Raimundo , Smits Veronique A. J. 
Published: March 2021

AbstractBackgroundUbiquitin‐specific protease 7 (USP7) belongs to the group of deubiquitinating enzymes (DUBs), which remove ubiquitin which controls various cellular processes such as chromosome segregation, DNA repair, gene expression, protein localization, kinase activity, protein degradation, cell cycle progression, and apoptosis. It is critical for several important functions in the cell, and therefore dysregulation of USP7 can contribute to tumorigenesis.ObjectivesAlterations in the USP7 protein have been identified in various malignancies of humans. Our aim was to examine whether USP7 could be a potential therapeutic target in hematopoietic cancers of dogs.MethodsThe expression level of USP7 in lymphocytes from healthy dogs and canine lymphoma cells was determined, and the effect of USP7 inhibition on the vital functions of canine cancer cells was examined.ResultsWe showed that USP7 was overexpressed in lymphomas in dogs. The USP7 inhibitor P5091 has selective cytotoxic activity in canine lymphoma and leukemia cell lines. Our results indicate that inhibition of USP7 leads to a disruption of cell cycle progression, and triggers DNA damage and apoptosis. The observed proapoptotic effect of the USP7 inhibitor most likely is not dependent on the p53 pathway.Conclusions and Clinical ImportanceOur results suggest that USP7 could be explored as a potential therapeutic target in dogs with lymphoma. The effectiveness of USP7 inhibition in malignant cells is predicted to be independent of their p53 status.
Myb10‐D confers PHS‐3D resistance to pre‐harvest sprouting by regulating NCED in ABA biosynthesis pathway of wheat
Authors: Lang Jing , Fu Yuxin , Zhou Yong , Cheng Mengping , Deng Min , Li Maolian , Zhu Tingting , Yang Jian , Guo Xiaojiang , Gui Lixuan , Li Linchuan , Chen Zhongxu , Yi Yingjin , Zhang Lianquan , Hao Ming , Huang Lin , Tan Chao , Chen Guoyue , Jiang Qiantao , Qi Pengfei , Pu Zhien , Ma Jian , Liu Zehou , Liu Yujiao , Luo Ming‐Cheng , Wei Yuming , Zheng Youliang , Wu Yongrui , Liu Dengcai , Wang JiRui 
Published: March 2021

Summary

Pre‐harvest sprouting (PHS), the germination of grain before harvest, is a serious problem resulting in wheat yield and quality losses.

Here, we mapped the PHS resistance gene PHS‐3D from synthetic hexaploid wheat to a 2.4 Mb presence–absence variation (PAV) region and found that its resistance effect was attributed to the pleiotropic Myb10‐D by integrated omics and functional analyses.

Three haplotypes were detected in this PAV region among 262 worldwide wheat lines and 16 Aegilops tauschii, and the germination percentages of wheat lines containing Myb10‐D was approximately 40% lower than that of the other lines. Transcriptome and metabolome profiling indicated that Myb10‐D affected the transcription of genes in both the flavonoid and abscisic acid (ABA) biosynthesis pathways, which resulted in increases in flavonoids and ABA in transgenic wheat lines. Myb10‐D activates 9‐cis‐epoxycarotenoid dioxygenase (NCED) by biding the secondary wall MYB‐responsive element (SMRE) to promote ABA biosynthesis in early wheat seed development stages.

We revealed that the newly discovered function of Myb10‐D confers PHS resistance by enhancing ABA biosynthesis to delay germination in wheat. The PAV harboring Myb10‐D associated with grain color and PHS will be useful for understanding and selecting white grained PHS resistant wheat cultivars.
What do unions do… with digital technologies? An affordance approach
Authors: Hennebert Marc‐Antonin , Pasquier Vincent , Lévesque Christian 
Published: March 2021

AbstractThis article examines the affordances that digital technologies offer to labour unions. The results of our study of 13 trade unions in Canada contrast with the prevailing techno‐deterministic perspectives in the literature which describe digital technologies as fundamentally good, bad or neutral for unions. By adopting an affordance approach, our paper examines how union actors perceive digital technology utility and constraints across five union core functions. The study identifies four digital information and communication technology affordances for unions (visibility, intensification, aggregation and addressability) and contributes to the literature on union renewal by showing how these affordances interact in a complex way and can reinforce trade unions' capabilities.
Gender and ethnic diversity in global ophthalmology and optometry association leadership: a time for change
Authors: Yashadhana Aryati , Clarke Neriah A , Zhang Justine H , Ahmad Jawad , Mdala Shaffi , Morjaria Priya , Yoshizaki Miho , Kyari Fatima , Burton Matthew J , Ramke Jacqueline 
Published: March 2021

AbstractPurposeTo assess the diversity of leadership bodies of member organisations of the International Council of Ophthalmology (ICO) and the World Council of Optometry (WCO) in terms of: (1) the proportion who are women in all world regions, and (2) the proportion who are ethnic minority women and men in Eurocentric high‐income regions.MethodsWe undertook a cross‐sectional study of board members and chairs of ICO and WCO member organisations using a desk‐based assessment of member organisation websites during February and March 2020. Gender and ethnicity of board members and chairs were collected using a combination of validated algorithmic software and manual assessment, based on names and photographs where available. Gender proportions were calculated across Global Burden of Disease super‐regions, and gender and ethnicity proportions in the high‐income regions of Australasia, North America and Western Europe.ResultsGlobally, approximately one in three board members were women for both ICO (34%) and WCO (35%) members, and one in three ICO (32%) and one in five WCO (22%) chairpersons were women. Women held at least 50% of posts in only three of the 26 (12%) leadership structures assessed; these were based in Latin America and the Caribbean (59% of WCO board positions held by women, and 56% of WCO chairs), and Southeast Asia, East Asia and Oceania (55% of ICO chairs). In the Eurocentric high‐income regions, white men held more than half of all board (56%) and chair (58%) positions and white women held a further quarter of positions (26% of board and 27% of chair positions). Ethnic minority women held the fewest number of board (6%) and chair (7%) positions.ConclusionsImprovements in gender parity are needed in member organisations of the WCO and ICO across all world regions. In high‐income regions, efforts to address inequity at the intersection of gender and ethnicity are also needed. Potential strategies to enable inclusive leadership must be centred on structurally enabled diversity and inclusion goals to support the professional progression of women, and people from ethnic minorities in global optometry and ophthalmology.
Time trends of childhood food allergy in China: Three cross‐sectional surveys in 1999, 2009, and 2019
Authors: Ma Zhuoying , Chen Lin , Xian Ruoling , Fang Heping , Wang Juan , Hu Yan 
Published: March 2021

AbstractBackgroundMany countries have recorded the trends of food allergy (FA) prevalence. Little is known about epidemiologic trends of childhood FA in China.MethodsIn three cross‐sectional surveys conducted in 1999, 2009, and 2019, the prevalence of and characteristic changes in FA in children aged ≤ 2 years were assessed and the outcomes were compared. All the children were recruited during well‐baby check‐ups at the Children's Hospital of Chongqing Medical University. All participants had a detailed medical history taken and underwent skin prick tests using ten commercial food extracts. Open food challenges were used for confirmation of FA.ResultsThe three studies included 1228 children (314 in 1999, 401 in 2009, and 513 in 2019; response rate > 95%). The prevalence of FA in 2009 (7.7%) and 2019 (11.1%) was significantly higher than that in 1999 (3.5%). However, there was no statistically significant difference in prevalence between 2009 and 2019 (P = .086). There was evidence of increased prevalence in CMPA between 1999 and 2019 (1.6% versus 5.7%; P = .004). However, no statistic difference was found in egg allergy (2.9% versus 5.5%; P = .21). The incidence of skin symptoms did not differ significantly over the study period, while the incidence of gastrointestinal symptoms increased significantly (18.2% in 1999, 12.9% in 2009, and 43.9% in 2019; P < .05).ConclusionsThe prevalence of FA in children rapidly increased after the 1990s and gradually stabilized after 2010. Cow's milk has become the most common food allergen among children in Chongqing. The incidence of gastrointestinal symptoms as a manifestation of FA has increased significantly since 2010.