bluuebunny/crossref_metadata_2025_split huggingface dataset:
Colony composition and nutrient analysis of Polyrhachis dives ants, a natural prey of the Chinese pangolin (Manis pentadactyla)
Authors: Xu Na , Yu Jiaming , Zhang Fuhua , Wu Shibao , Zou Cuiyun , Wang Qiaoyun , Wang Yifu 
Published: October 2021

AbstractThe Chinese pangolin (Manis pentadactyla) is a critically endangered mammal with a highly specialized diet. To enhance nutritional knowledge of its diet, we analyzed the colony composition of a nest of Polyrhachis dives ants, which is the key natural prey in the Chinese pangolin's diet. In addition, we determined the nutrient composition of the total colony compared with adult ants. Nutrients quantified in this study included: crude protein, crude fat, carbohydrate, and amino acids, minerals, and vitamins, as well as formic acid and chitin, which have not been reported in previous diet studies. Our results showed that the colony consisted of adults (82%), pupae (10%), larvae (7%), and eggs (1%) (fresh mass). Both the total colony and adult ants, respectively, contained high concentrations of crude protein (62.97% and 64.68%), chitin (49.25% and 60.40%), crude fat (10.12% and 9.91%) (dry matter basis), and formic acid (2.06% and 3.07%) (fresh mass). This implies that Chinese pangolin might prefer prey with high protein, high chitin, low fat, and low formic acid content. Colony and adult ants differed in chemical composition in many aspects, thus it might be unsuitable to feed Chinese pangolin with only adult ants. Chitin and formic acid may play important roles in the diet and selectivity of Chinese pangolin. This study provides reference information that may be useful for developing better artificial diets with more comprehensive nutrient compositional data to meet the nutritional requirements of the Chinese pangolin under managed feeding programs.
Fisheries Governance
Authors: Fabinyi Michael , Barclay Kate 
Published: October 2021

AbstractThis chapter examines the role that governance plays in shaping fishing livelihoods. This includes formal government regulation as well as other factors that shape fishing, such as markets, buyer requirements and social norms. Institutional arrangements serve as a key component of fishing livelihoods, by prescribing the conditions under which fishing livelihoods operate. In this chapter we sketch out some of the trends in fisheries governance across parts of the Asia-Pacific, before discussing examples in Australia and Indonesia.
On partition functions of refined Chern-Simons theories on S3
Authors: Avetisyan M.Y. , Mkrtchyan R.L. 
Published: October 2021

Abstract
We present a new expression for the partition function of the refined Chern-Simons theory on S3 with an arbitrary gauge group, which is explicitly equal to 1 when the coupling constant is zero. Using this form of the partition function we show that the previously known Krefl-Schwarz representation of the partition function of the refined Chern-Simons theory on S3 can be generalized to all simply laced algebras.For all non-simply laced gauge algebras, we derive similar representations of that partition function, which makes it possible to transform it into a product of multiple sine functions aiming at the further establishment of duality with the refined topological strings.
Dynamical Cobordism and Swampland Distance Conjectures
Authors: Buratti Ginevra , Calderón-Infante José , Delgado Matilda , Uranga Angel M. 
Published: October 2021

AbstractWe consider spacetime-dependent solutions to string theory models with tadpoles for dynamical fields, arising from non-trivial scalar potentials. The solutions have necessarily finite extent in spacetime, and are capped off by boundaries at a finite distance, in a dynamical realization of the Cobordism Conjecture. We show that as the configuration approaches these cobordism walls of nothing, the scalar fields run off to infinite distance in moduli space, allowing to explore the implications of the Swampland Distance Conjecture. We uncover new interesting scaling relations linking the moduli space distance and the SDC tower scale to spacetime geometric quantities, such as the distance to the wall and the scalar curvature. We show that walls at which scalars remain at finite distance in moduli space correspond to domain walls separating different (but cobordant) theories/vacua; this still applies even if the scalars reach finite distance singularities in moduli space, such as conifold points.We illustrate our ideas with explicit examples in massive IIA theory, M-theory on CY threefolds, and 10d non-supersymmetric strings. In 4d$$ \mathcal{N} $$N= 1 theories, our framework reproduces a recent proposal to explore the SDC using 4d string-like solutions.
Optimum breeding strategies using genomic and phenotypic selection for the simultaneous improvement of two traits
Authors: Marulanda Jose J. , Mi Xuefei , Utz H. Friedrich , Melchinger Albrecht E. , Würschum Tobias , Longin C. Friedrich H. 
Published: October 2021

AbstractKey messageA breeding strategy combining genomic with one-stage phenotypic selection maximizes annual selection gain for net merit. Choice of the selection index strongly affects the selection gain expected in individual traits.AbstractSelection indices using genomic information have been proposed in crop-specific scenarios. Routine use of genomic selection (GS) for simultaneous improvement of multiple traits requires information about the impact of the available economic and logistic resources and genetic properties (variances, trait correlations, and prediction accuracies) of the breeding population on the expected selection gain. We extended the R package “selectiongain” from single trait to index selection to optimize and compare breeding strategies for simultaneous improvement of two traits. We focused on the expected annual selection gain (ΔGa)for traits differing in their genetic correlation, economic weights, variance components, and prediction accuracies of GS. For all scenarios considered, breeding strategyGSrapid(one-stage GS followed by one-stage phenotypic selection) achieved higher ΔGathan classical two-stage phenotypic selection, regardless of the index chosen to combine the two traits and the prediction accuracy of GS. The Smith–Hazel or base index delivered higher ΔGafor net merit and individual traits compared to selection by independent culling levels, whereas the restricted index led to lowerΔGain net merit and divergent results for selection gain of individual traits. The differences among the indices depended strongly on the correlation of traits, their variance components, and economic weights, underpinning the importance of choosing the selection indices according to the goal of the breeding program. We demonstrate our theoretical derivations and extensions of the R package “selectiongain” with an example from hybrid wheat by designing indices to simultaneously improve grain yield and grain protein content or sedimentation volume.
Toy story or children story? Putting children and their rights at the forefront of the artificial intelligence revolution
Authors: Fosch-Villaronga E. , van der Hof S. , Lutz C. , Tamò-Larrieux A. 
Published: October 2021

AbstractPolicymakers need to start considering the impact smart connected toys (SCTs) have on children. Equipped with sensors, data processing capacities, and connectivity, SCTs targeting children increasingly penetrate pervasively personal environments. The network of SCTs forms the Internet of Toys (IoToys) and often increases children's engagement and playtime experience. Unfortunately, this young part of the population and, most of the time, their parents are often unaware of SCTs’ far-reaching capacities and limitations. The capabilities and constraints of SCTs create severe side effects at the technical, individual, and societal level. These side effects are often unforeseeable and unexpected. They arise from the technology's use and the interconnected nature of the IoToys, without necessarily involving malevolence from their creators. Although existing regulations and new ethical guidelines for artificial intelligence provide remedies to address some of the side effects, policymakers did not develop these redress mechanisms having children and SCTs in mind. This article provides an analysis of the arising side effects of SCTs and contrasts them with current regulatory redress mechanisms. We thereby highlight misfits and needs for further policymaking efforts.
Immune checkpoint inhibitor-related thrombocytopenia: incidence, risk factors and effect on survival
Authors: Haddad Tyler C. , Zhao Songzhu , Li Mingjia , Patel Sandip H. , Johns Andrew , Grogan Madison , Lopez Gabriella , Miah Abdul , Wei Lai , Tinoco Gabriel , Riesenberg Brian , Li Zihai , Meara Alexa , Bertino Erin M. , Kendra Kari , Otterson Gregory , Presley Carolyn J. , Owen Dwight H. 
Published: October 2021

Abstract
Introduction
Immune checkpoint inhibitors (ICI) are associated with unique immune-related adverse events (irAEs). Immune-related thrombocytopenia (irTCP) is an understudied and poorly understood toxicity; little data are available regarding either risk of irTCP or the effect of irTCP on clinical outcomes of patients treated with ICI.

Methods
We conducted a retrospective review of sequential cancer patients treated with ICI between 2011 and 2017 at our institution. All patients who received ICI alone or in combination with other systemic therapy in any line of treatment were included; those with thrombocytopenia ≥ grade 3 at baseline were excluded. We calculated the incidence of ≥ grade 3 irTCP and overall survival (OS). Patient factors associated with irTCP were assessed.

Results
We identified 1,038 patients that met eligibility criteria. Overall, 89 (8.6%) patients developed grade ≥ 3 thrombocytopenia; eighteen were attributed to ICI (1.73% overall). Patients who developed grade ≥ 3 irTCP had worse overall survival compared to those whose thrombocytopenia was unrelated to ICI (4.17 vs. 10.8 month; HR. 1.94, 95% CI 1.13, 3.33; log-rank p = 0.0164). Patients with grade ≥ 3 irTCP also had worse survival compared to those without thrombocytopenia (4.17 vs. 13.31 months; HR 2.22, 95% CI 1.36, 3.62; log-rank p = 0.001). The incidence of irTCP appeared lowest among those treated with PD-1/L1 monotherapy (p = 0.059) and was not associated with cancer type, smoking status, age, gender, race, or line of therapy.

Conclusions
Unlike other irAEs, we found that irTCP was associated with worse overall survival. The incidence of irTCP appeared lowest among those treated with PD-1/L1 monotherapy.
Use of PET-CT in diagnostic workup of periprosthetic infection of hip and knee joints: significance in detecting additional infectious focus
Authors: Roschke E. , Kluge T. , Stallkamp F. , Roth A. , Zajonz D. , Hoffmann K. T. , Sabri O. , Kluge R. , Ghanem M. 
Published: October 2021

Abstract
Introduction
The diagnosis and management of periprosthetic knee and hip infections as well as the identification and management of possible additional infectious foci is of great importance for successful therapy. This study analyses the importance of 18F deoxyglucose PET-CT (PET-CT) in the identification of additional infectious focus and subsequent impact on management of periprosthetic infection (PPI).

Material and methods
A retrospective analysis of the clinical data and findings in the period from January 2008 to December 2018 was carried out. One hundred and four patients with in-hospital treatment due to PPI of a hip or knee joint were identified and included in this study. All patients underwent a standardized clinical examination and further surgical and antibiotic therapy. The reevaluation of performed PET-CTs was specifically carried out with regard to the local PPI or detection of secondary foci.

Results
PET-CT successfully verified the PPI in 84.2% of the patients. A total of 78 possible additional foci were detected in PET-CT in 56 (53.8%) of the examined patients. Predilection sites for possible secondary foci were joints (42.3%), pulmonary (15.4%), ear-nose-throat (15.4%), spine (11.5%), and the musculocutaneous tissues (11.5%). Fifty-four positive PET-CT findings were confirmed clinically with need of additional adequate treatment.

Conclusion
PET-CT is a valuable diagnostic tool to confirm periprosthetic joint infection. At the same time, the whole-body PET/CT may detect additional foci of infection with impact on subsequent treatment strategy. PET was of special value in detecting infections at distant locations far from the primary infected joint in significant number. These distant infection locations can be potential cause of a re-infection. This clearly reflects the need of their diagnosis.
Object-based illumination transferring and rendering for applications of mixed reality
Authors: Xu Di , Li Zhen , Cao Qi 
Published: October 2021

AbstractIn applications of augmented reality or mixed reality, rendering virtual objects in real scenes with consistent illumination is crucial for realistic visualization experiences. Prior learning-based methods reported in the literature usually attempt to reconstruct complicated high dynamic range environment maps from limited input, and rely on a separate rendering pipeline to light up the virtual object. In this paper, an object-based illumination transferring and rendering algorithm is proposed to tackle this problem within a unified framework. Given a single low dynamic range image, instead of recovering lighting environment of the entire scene, the proposed algorithm directly infers the relit virtual object. It is achieved by transferring implicit illumination features which are extracted from its nearby planar surfaces. A generative adversarial network is adopted in the proposed algorithm for implicit illumination features extraction and transferring. Compared to previous works in the literature, the proposed algorithm is more robust, as it is able to efficiently recover spatially varying illumination in both indoor and outdoor scene environments. Experiments have been conducted. It is observed that notable experiment results and comparison outcomes have been obtained quantitatively and qualitatively by the proposed algorithm in different environments. It shows the effectiveness and robustness for realistic virtual object insertion and improved realism.
Die laienverständliche Version der 2018 EULAR Empfehlungen zu körperlicher Aktivität von Menschen mit entzündlich-rheumatischen und degenerativen Erkrankungen
Authors: Niedermann K. , Rausch A. K. , Braun J. , Becker H. , Böhm P. , Bräm R. , Gilliam-Feld G. , Kiefer D. , Kurz R. , Schönfelder M. , Stamm T. , Kiltz U. 
Published: October 2021

Zusammenfassung
Hintergrund
Körperliche Aktivität und spezifisches Training haben großen gesundheitlichen Nutzen. Empfehlungen zum Management von rheumatoider Arthritis (RA), Spondyloarthritis (SpA) sowie Hüft- und Kniegelenkarthose (HKA) sind bisher in Bezug auf Art und Dosierung aber unspezifisch. Darum wurden die 2018 EULAR Empfehlungen zu körperlicher Aktivität für Menschen mit entzündlich-rheumatischen und degenerativen Erkrankungen formuliert. Sie bestehen aus 4 übergeordneten Prinzipien und 10 Empfehlungen. Die EULAR Bewegungsempfehlungen wurden auch als laienverständliche Version in englischer Sprache publiziert.

Ziel
Übersetzung der laienverständlichen Version ins Deutsche und sprachliche Validierung in Deutschland, Österreich und der Schweiz.

Methoden
Eine professionelle Übersetzung ins Deutsche wurde von den Autor*innen einschließlich Personen mit RA, SpA und HKA zu einer präfinalen Version bearbeitet. Anschließend wurden in den 3 Ländern je 8 Interviews mit Personen mit RA, SpA und HKA durchgeführt, um die Verständlichkeit, Wortwahl, Vollständigkeit und Umsetzbarkeit zu prüfen. Die Patientenvertreter*innen der Autor*innengruppe bewerteten anonym ihre Zustimmung zur finalen Version auf einer Skala von 0 bis 10.

Ergebnisse
Die professionelle Übersetzung wurde von den Autor*innen und auf Grundlage der Interviews substanziell überarbeitet. Dabei wurden Formulierungen angepasst, um Lesbarkeit und Verständlichkeit zu verbessern und Aussagen zu präzisieren. Inhalt und Struktur des Originaltextes wurden dabei nicht verändert. Die Zustimmung zu den einzelnen Empfehlungen lag zwischen 10 (SD 0) und 7,6 (SD 1,67).

Diskussion
Für Menschen mit RA/SpA/HKA sollten die EULAR Bewegungsempfehlungen in deren Muttersprache vorliegen. Die laienverständliche deutsche Version ist valide und wurde in allen 3 Ländern gut akzeptiert. Damit können die EULAR Bewegungsempfehlungen verständlich und praktikabel vermittelt werden.
Peri-implant fracture: a rare complication after intramedullary fixation of trochanteric femoral fracture
Authors: Halonen Lauri M. , Stenroos Antti , Vasara Henri , Kosola Jussi 
Published: October 2021

Abstract
Introduction
Trochanteric femoral fractures are among the most common operatively treated fractures. Intramedullary fixation has become the treatment of choice in many centers around the world. Nevertheless, the knowledge of rare complications of these fractures is limited. In this study, the incidence and treatment strategies for peri-implant fractures (PIF) were assessed.

Materials and methods
A single-center retrospective cohort study was done on 987 consecutive operatively treated trochanteric fractures. PFNA cephalomedullary nail was used as a fixation method. All patients were followed up from patient records for peri-implant fractures. Plain radiographs as well as different salvage methods were analyzed and compared.

Results
The total rate of peri-implant fractures was 1.4% (n = 14). The rate of PIF for patients treated with short (200 mm) nails, intermediate-length (240 mm) nails, and long nails was 2.7% (n = 2), 1.5% (n = 11), and 0.7% (n = 1), respectively (ns, p > 0.05 for difference). Treatment of choice for PIF was either ORIF with locking plate (57%, n = 8) or exchange nailing (43%, n = 6). None of the PIF patients needed additional surgeries for non-union, malunion, or delayed union.

Conclusions
A PIF is a rare complication of intramedullary fixation of trochanteric fractures. It can be treated with either locking plates or exchange nailing with sufficient results. There are no grounds for favoring long nails to avoid PIFs.
Notes on the creation and manipulation of solid solution models
Authors: Myhill Robert , Connolly James A. D. 
Published: October 2021

AbstractA large class of solid solution models are formulated on the premise that exchange of chemical species takes place on a finite number of unique crystallographic sites, and that the thermodynamic properties of the solution are a function of the proportions of species occupying each of the sites. These models are broadly classified as being of Bragg–Williams-type. They form an excellent first order approximation of non-ideal mixing and long-range order. In this article we present the mathematical framework common to all Bragg–Williams models, introducing necessary concepts from geometry, set theory and linear algebra. We combine this with a set of mathematical tools which we have found useful in building and using such models. We include several worked examples to illustrate key concepts and provide general expressions which can be used for all models. This paper is split into two parts. In the first part, we show how the valences of the species occupying each site and the total charge of the species involved in site exchange are sufficient to define the space of valid site occupancies of a solid solution, and to compute the endmembers bounding that space. We show that this space can be visualised as a polytope, i.e, an n-dimensional polyhedron, and we describe the relationship between site-occupancy space and compositional space. In the second part of the paper, we present the linear algebra required to transform descriptions of modified van Laar and subregular solution models from one independent endmember basis to another. The same algebra can also be used to derive macroscopic endmember interactions from microscopic site interactions. This algebra is useful both in the initial design of solution models, and when performing thermodynamic calculations in restricted chemical subsystems. A polytope description of solid solutions is used in the thermodynamic software packages Perple_X and burnman. The algorithms described in this paper are made available as python code.
Impact of pulse oximetry screening to detect congenital heart defects: 5 years’ experience in a UK regional neonatal unit
Authors: Singh Yogen , Chen Si Emma 
Published: October 2021

AbstractPulse oximetry screening (POS) has been shown to be an effective, non-invasive investigation that can detect up to 50–70% of previously undiagnosed congenital heart defects (CHDs). The aims of this study were to assess the accuracy of POS in detection of CHDs and its impact on clinical practice. All eligible newborn infants born between 1 Jan 2015 and 31 Dec 2019 in a busy regional neonatal unit were included in this prospective observational study. A positive POS was classified as two separate measurements of oxygen saturation < 95%, or a difference of > 2% between pre- and post-ductal circulations. Overall, 23,614 infants had documented POS results. One hundred eighty nine (0.8%) infants had a true positive result: 6 had critical CHDs, 9 serious or significant CHDs, and a further 156/189 (83%) infants had significant non-cardiac conditions. Forty-three infants who had a normal POS were later diagnosed with the following categories of CHDs post-hospital discharge: 1 critical, 15 serious, 20 significant and 7 non-significant CHDs. POS sensitivity for detection of critical CHD was 85.7%, whereas sensitivity was only 33% for detection of major CHDs (critical and serious) needing surgery during infancy; specificity was 99.3%.Conclusion: Pulse oximetry screening showed moderate to high sensitivity in detection of undiagnosed critical CHDs; however, it failed to detect two-third of major CHDs. Our study further emphasises the significance of adopting routine POS to detect critical CHDs in the clinical practice. However, it also highlights the need to develop new, innovative methods, such as perfusion index, to detect other major CHDs missed by current screening tools.

What is Known:• Pulse oximetry screening is cost effective, acceptable, easy to perform and has moderate sensitivity and high specificity in detection of critical congenital heart defects.• Pulse oximetry screening has been implemented many countries including USA for detection of critical congenital heart defects, but it is not currently recommended by the UK National Screening Committee.

What is New:• To our knowledge, this is the first study describing postnatal detection and presentation of all the infants with congenital heart defects over a period of 5 years, including those not detected on the pulse oximetry screening, on the clinical practice. • It emphasises that further research required to detect critical congenital heart defects and other major CHDs which can be missed on the screening tools currently employed in clinical practice.