bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between intracytoplasmic sperm injection and neurodevelopmental outcomes among offspring
Authors: Wang Cheng-Wei , Chang Tzu-Hao , Chuang Nai-Chen , Au Heng-Kien , Chen Chi-Huang , Tseng Sung-Hui 
Published: September 2021

PurposeTo compare the risk of neurodevelopmental disorders in children conceived via intracytoplasmic sperm injection (ICSI) and those conceived naturally.Materials and methodsA population-based cohort study using data retrieved from the Taipei Medical University Research Database (TMURD) from January, 2004 to August, 2016. The data included maternal pregnancy history, perinatal history and developmental follow up of their babies up to 5 years of age. The study included 23885 children, of whom 23148 were naturally conceived and 737 were conceived via ICSI. Neurodevelopmental disorders defined by 21 ICD-9-CM codes.ResultsOf the 23885 children enrolled for analysis, 2778 children were included for further subgrouping analysis after propensity matching to reduce bias from maternal factors. The single-birth group included 1752 naturally conceived (NC) children and 438 ICSI children. The multiple-birth group included 294 NC and 294 ICSI children. The risk of neurodevelopmental disorders was not increased for ICSI children in both groups (single birth: adjusted hazard ratio aHR = 0.70, 95% CI = 0.39–1.27,p= 0.243; multiple-birth group aHR = 0.77, 95% CI = 0.43–1.35,p= 0.853). In the single-birth group, multivariate analyses showed that male sex (aHR = 1.81, 95% CI = 1.29–2.54,p< 0.001), and intensive care unit (ICU) admission (aHR = 3.10, 95% CI = 1.64–5.86,p< 0.001) were risk factors for neurodevelopmental disorders. In the multiple-birth group, multivariate analyses demonstrated that ICU admission (aHR = 3.58, 95% CI = 1.82–7.04,p< 0.001), was risk factor for neurodevelopmental disorders.ConclusionOur study indicated that the use of ICSI does not associated with higher risk of neurodevelopmental disorders in the offspring. But male sex, and ICU admission do have increased risk of neurodevelopmental disorders. However, long term follow up of this cohort on health outcomes in adolescence and adulthood will strengthen the conclusions that ICSI is safe regarding offspring long term outcome.
Changes in central venous-to-arterial carbon dioxide tension induced by fluid bolus in critically ill patients
Authors: Pierrakos Charalampos , De Bels David , Nguyen Thomas , Velissaris Dimitrios , Attou Rachid , Devriendt Jacques , Honore Patrick M. , Taccone Fabio Silvio , De Backer Daniel 
Published: September 2021

BackgroundIn this prospective observational study, we evaluated the effects of fluid bolus (FB) on venous-to-arterial carbon dioxide tension (PvaCO2) in 42 adult critically ill patients with pre-infusion PvaCO2> 6 mmHg.ResultsFB caused a decrease in PvaCO2, from 8.7 [7.6−10.9] mmHg to 6.9 [5.8−8.6] mmHg (p < 0.01). PvaCO2decreased independently of pre-infusion cardiac index and PvaCO2changes during FB were not correlated with changes in central venous oxygen saturation (ScvO2) whatever pre-infusion CI. Pre-infusion levels of PvaCO2were inversely correlated with decreases in PvaCO2during FB and a pre-infusion PvaCO2value < 7.7 mmHg could exclude a decrease in PvaCO2during FB (AUC: 0.79, 95%CI 0.64–0.93; Sensitivity, 91%; Specificity, 55%; p < 0.01).ConclusionsFluid bolus decreased abnormal PvaCO2levels independently of pre-infusion CI. Low baseline PvaCO2values suggest that a positive response to FB is unlikely.
A systematic review of the menstrual experiences of university students and the impacts on their education: A global perspective
Authors: Munro Alana K. , Hunter Erin C. , Hossain Syeda Z. , Keep Melanie 
Published: September 2021

BackgroundHigher education attainment is linked to improved health and employment outcomes but the impact of university students’ experiences of menstruation on their education is less clear. The objective of this review was to synthesise qualitative and quantitative research on university students’ menstrual experiences and educational impacts.MethodsEligible studies were identified through systematic searching across eight peer-reviewed databases, websites for menstrual health organisations, grey literature databases, and reference lists of included studies. Eligible studies must have reported on at least one of the antecedents or components of menstrual experience outlined in the integrated model of menstrual experience in relation to university students or reported on the impact of their menstrual experiences on their education. Study characteristics and findings were extracted, analysed and presented as a narrative synthesis. The quality of evidence was assessed with the Mixed Methods Appraisal Tool. This study is registered on PROSPERO, number CRD42020178470.ResultsEighty-three studies were eligible for inclusion. Most studies (n = 74; 89%) were quantitative and the highest proportion of studies were conducted in lower-middle-income countries (n = 31; 37%). Self-reported dysmenorrhea, other physical and emotional menstrual-related symptoms, and menstrual stigma contributed to negative menstrual experiences among female students. Very few studies considered the menstrual experiences of non-binary and transgender menstruating students, and culturally diverse students. Dysmenorrhea contributed to university absenteeism, impaired participation and concentration, and declining academic performance. Inadequate sanitation facilities for menstrual management and challenges containing menstruation also negatively impacted education.ConclusionsFemale university students’ experiences of menstruation can negatively impact their education, highlighting the need for program and policy responses at university to improve students’ wellbeing and educational engagement. Further research on the menstrual experiences of gender diverse, migrant and international students is needed as there is insufficient evidence to date.
Prevalence and molecular characterization of antibiotic resistance and associated genes in Klebsiella pneumoniae isolates: A clinical observational study in different hospitals in Chattogram, Bangladesh
Authors: Tanni Afroza Akter , Hasan Md. Mahbub , Sultana Nahid , Ahmed Wazir , Mannan Adnan 
Published: September 2021

Objective
This study was performed to investigate the prevalence of multidrug resistance and molecular characterization of Klebsiella pneumoniae (KPN) from clinical isolates in the southern region of Bangladesh. Additional analysis of the prevalence of blaNDM-1, blaSHV-11, uge genes of KPN was also carried out among these clinical isolates.

Method
The study was carried out using 1000 clinical isolates collected from two different hospitals of Chattogram. A drug susceptibility test was performed by the disk diffusion method to detect KPN’s response to 16 antibiotics. The presence of antibiotic-resistant and (or) virulent genes blaNDM-1, blaSHV-11, uge were investigated using the PCR technique. Isolates having blaNDM-1, blaSHV-11, uge gene were further validated by sequencing followed by phylogenetic analysis. Phylogenetic relationships among these isolates were determined by Clustal omega and MEGA7.

Result
A total of 79%, 77%, 74.9%, 71%, 66% and 65% isolates exhibited resistance against cefuroxime, cefixime, cefotaxime, ceftazidime, cefepime and ceftriaxone respectively. The frequency of resistance to other antibiotics varied from 26.5% to 61.8%. PCR analysis showed that 64% of strains harbored blaNDM-1 gene, and 38% strains harbored blaSHV-11 gene. Moreover, 47% of samples were carrying uge gene, and 19% of samples carried blaNDM-1, blaSHV-11, uge genes together.

Conclusion
In this study, we’ve analysed the pattern of expression as well as prevalence of blaNDM-1, blaSHV-11, and uge genes in Klebsiella isolates. Upon molecular and statistical analysis, we found a high prevalence of multi-drug resistance KPN strains in the isolates. The Klebsiella isolates were confirmed to harbor multiple ESBL genes and 64% of the isolates were found to be producing NDM-1. As multidrug resistance is an alarming issue, continuous surveillance and routine clinical detection of resistant bacteria and plasmids are necessary to prevent catastrophic public health incidents.
Relative Adrenal Insufficiency in Decompensated Cirrhotic Children: Does It Affect Outcome?
Authors: Tripathi Parijat Ram , Sen Sarma Moinak , Yachha Surender Kumar , Aggarwal Amita , Bhatia Vijayalakshmi , Kumar Anup , Srivastava Anshu , Poddar Ujjal 
Published: September 2021

INTRODUCTION:
Relative adrenal insufficiency (RAI) is associated with poor outcome in adult cirrhotics. So far, pediatric studies are not available on the same. We aimed to prospectively study the presence and outcome of RAI in children with decompensated cirrhosis over 180 days.

METHODS:
Hemodynamically stable children with decompensated cirrhosis were sampled for serum basal cortisol and peak cortisol (after 30 minutes of 1-μg intravenous Synacthen) at day 1 and day 21. RAI was diagnosed as peak cortisol <500 nmol/L. Serum cytokines (interleukin-6 and tumor necrosis factor-α) and lipid profile were correlated with RAI. Cohort was followed up for outcomes over 180 days for complications and survival. With the identified risk factors, prognostic models were derived and compared with pediatric end-stage liver disease (PELD) and Child-Turcotte-Pugh scores.

RESULTS:
Prevalence of RAI was 54% at baseline and 61% at day 21 in the enrolled patients (n = 63, aged 128 ± 48 months, male 78%). No significant differences in cytokines and serum lipid levels were seen between RAI and normal adrenal function groups. Patients with RAI at baseline (D1-RAI) developed higher complications at follow-up as compared to the normal adrenal function group (53% vs 24%, P = 0.02). The PELD score (odds ratio 1.08, confidence interval 1.05–1.12, P < 0.01) and D1-RAI (odds ratio 3.19, confidence interval 1.32–7.73, P = 0.01) were independent predictors of follow-up complications. The PELD-delta cortisol model (area under the receiver operating curve 0.84, P < 0.001, 92% sensitivity; 60% specificity) predicted morbidity better than isolated PELD or Child-Turcotte-Pugh scores.

DISCUSSION:
RAI is a risk factor for development of complications in pediatric cirrhosis over short-term follow-up. The PELD-delta cortisol score is a promising prognostic model for predicting follow-up complications.
Song Recommendation Application Using Speech Emotion Recognition
Authors: Setiawan Eko Budi , Iqbal Dzulfiqar Al Ghani 
Published: September 2021

This research was conducted to facilitate the interaction between radio broadcasters and radio listeners during the song request process. This research was triggered by the difficulty of the broadcasters in monitoring song requests from listeners. The system is made to accommodate all song requests by listeners. The application produced in this study uses speech emotion recognition technology based on a person's mood obtained from the spoken words. This technology can change the voice into one of the mood categories: neutral, angry, sad, and afraid. The k-Nearest Neighbor method is used to get recommendations for recommended song titles by looking for the closeness of the value between the listener's mood and the availability of song playlists. kNN is used because this method is suitable for user-based collaborative problems. kNN will recommend three songs which then be offered to listeners by broadcasters. Based on tests conducted to the broadcasters and radio listeners, this study has produced a song request application by recommending song titles according to the listener's mood, the text message, the searching songs, and the song requests and the song details that have been requested. Functional test that has been carried out has received 100 because all test components have succeeded as expected.
Familial Factors Influencing Creativity Among Married Employees of Financial Technology Organisations in Lagos
Authors: Balogun Shyngle K. , Attah Thomas , Famakinde Oluwafemi P. 
Published: September 2021

Creativity in the workplace is absolutely essential, especially in a financial technology organization in today’s global society. A detailed literature review reveals unclear connection of creativity with some family-related variables among married employees. This study is a further exploration to establish the role of familial factors such as commitment to marriage, marital satisfaction, religiosity and familism in the creativity of FINTECH employees in Lagos, Nigeria.
The research was a cross-sectional survey of married employees within FINTECH organizations in Lagos. 224 married employees (135 are males) were conveniently sampled to respond to a structured questionnaire of six sections made up of validated scales that measured constructs of marital commitment, marital satisfaction, religiosity, familism and creativity. Three hypotheses were tested using Pearson product moment correlation, multiple regression analysis and t-test for independent samples at pα.05.
Creativity for FINTECH employees has a significant positive relationship with marital commitment (r=.468, p<.01), marital satisfaction (r=.224, p<.01), religiosity (r=.328, p<.01) and familism (r=.452, p<.01). Psychological factors (commitment to marriage, familism, marital satisfaction and religiosity) have a significant joint influence on employee creativity (F (4, 223) = 24.766, p <.01; R2 = .295) and a significant independent contribution of commitment to marriage and familism to employee creativity [(β = .358, p <.01); (β = .287, p <.01) respectively]. There are no significant gender differences in employee creativity (t (217) = 1.656, p > .05).
This confirms the hypothesized heightened relationship of familial factors with creativity of employees, especially FINTECH employees. This study rather brings a new suggestion that organizations should not just focus on the conditions of work at the office, or the pay of their employees only, but also give attention to the state of the family of their employees as this influences their abilities to deliver innovative ideas and lofty solutions to nutty problems within the work environment.
The adoption of the Chinese calendar and its impact on seasonal poetry in early Japan (c. 700 to 1000)
Authors: Leinss Gerhard 
Published: September 2021

Abstract
We have evidence that since the second half of the seventh century a common calendar has been shared among Japan’s political elite within an evolving state based on Chinese models. This paper discusses the impact its introduction had on the perception of time as revealed by the seasonal poetry of aristocrats who presumably had access to the calendar. Not only numerous poems on seasonal topics but also a substantial number of calendars is extant from that period. We can therefore anticipate what kind of calendars poets possibly had at their hands when pursuing their art. I argue that the impact the introduction of the common calendar had on seasonal poetry has been far greater and more complex than hitherto acknowledged by researchers, and that the underestimation of this impact is largely due to an incomplete understanding of the seasonal concepts of the adopted calendar which I intend to clarify with this paper.
موضوع الحضارة والثقافة الصينية في المحتوى العلمي لتدريس اللغة الصينية في مصر قسم اللغة الصينية بكلية آداب جامعة القاهرة نموذجًا / Chinese Civilization and Culture in the Content of Chinese Language Teaching in Egypt: Department of Chinese Language, Faculty of Arts, Cairo University as a Model
Authors: Fergan Mohsen 
Published: September 2021

Abstract
The courses of civilization and culture are covered within the content of many departments of the Chinese language in Egyptian universities, but only on miscellaneous information and selections chosen randomly from the chapters of the cultural and history of China. Inspite of its practical functions in general, educational and research process of the ancient culture of these Egyptian and Arab academic institutions require specialized scientific treatment in the coming days, to explore an educational approach to “culture” as a fifth language skill, and thus benefit from Chinese and international efforts in teaching the language and its culture.
نموذج التنمية المستدامة في الصين ومدى استفادة العرب منها / China’s Sustainable Development Model and How Arabs Benefit From it
Authors: Daher Massoud 
Published: September 2021

Abstract
Based on the development of positive relations between China and the Arab countries in the context of a new globalization on the path to a multipolar world, this study addresses the following methodological issues: China’s development achievements in the reform and the opening-up movement, China’s success in the face of the Covid-19 epidemic, and the analysis of the notion of “Sustainable Development” and the Chinese characteristics of the concept of socialism. Accurate scientific conclusions confirmed that sustainable development with Chinese characteristics constitutes a distinct model of rational and balanced development that achieved the well-being of the Chinese population. The Belt and Road Initiative has been widely welcomed in all Arab countries. Arab institutions, both official and private, have begun to study the Chinese development model to build a new style of development based on social stability, economic prosperity and mutual benefit. China is a leading model for promoting the common interest of people. China contributes positively to the well-being of its people and the rest of the world through cooperation. It is moving forward with high-quality development plans that provide new opportunities to revive the global economy, which is suffering from the drawbacks of the Covid-19 pandemic. Having presented China as a leading human model of inclusive development to realize the Chinese Dream, the enlightened Arab elites have shown increasing interest in this high-quality experiment that has succeeded in eradicating poverty, combating Covid-19, helping the recovery of the global economy, and promoting opportunities for advancement, innovation and creativity on a global level. Since China’s development was built on moral and humanitarian rules, it is warmly welcomed in the Arab countries because it affirms that humans are the greatest capital and the goal of sustainable development. It offers rich and useful lessons for everyone around the world.
Modified TDAE petroleum plasticiser
Authors: Ptak Stefan , Krasodomski Wojciech , Jakóbiec Janusz , Antosz Artur 
Published: September 2021

Abstract
Petroleum plasticisers are applied as softening additives in rubber vulcanisation processes and as components of rubber mixtures in the production and vulcanisation process. They contain polycyclic aromatic compounds exhibiting carcinogenic and mutagenic effects. Since 2010, the European Union has banned the use of high-aromatic DAE plasticisers. The petroleum industry and tyre manufacturers are developing new types of petroleum plasticisers. The best alternative to the DAE is the TDAE plasticisers, obtained mainly by selective solvent refining. The solvent dewaxing process of classic TDAE plasticisers was studied in order to improve the chemical composition as well as the rheological and low-temperature properties of deparafinate. This article presents the results of an examination of the TDAE plasticiser samples subjected to solvent dewaxing process on a laboratory scale with three types of solvents, MEK–TOL, MEK–MIBK and MEK–MTBE. It was demonstrated that solvent dewaxing of the TDAE plasticiser with positive pour points maintains good process selectivity and allows for a significant reduction of the plasticiser pour point, thus improving the rheological and low-temperature properties. In all dewaxing attempts, the pour point in the deparaffinate decreased significantly to the range −12 to −22°C, compared to the positive pour points of the raw materials. The application tests for two types of the TDAE plasticisers, used to produce oiled rubber and a standard rubber compound, meet the quality requirements for those products.
Reflections on the ‘Just Price’ in Times of Crisis (with Reference to Coronavirus … but not only)
Authors: Marchisio Emiliano 
Published: September 2021

Abstract
The debate about the ‘just price’ has ancient origin and returns forcefully to the scene when, in the event of crises of various kinds, there is a rapid and significant increase in prices of given goods or services. The main issue is whether price increases of such a nature could, or should, be considered illicit and ground the issue of sanctions against the firms increasing prices, thus focusing on a macro-systemic level of analysis. The central part of the article reviews different theories on what a ‘just price’ should be and focuses on the idea that a price is ‘just’ when it functions as an index of relative scarcity in free markets. It is claimed that such a function deserves protection by Italian and EU law. Therefore price adjustments in response to shocks cannot and should not be considered illegal: it is unacceptable to sanction private firms by attributing them the wrong of not having substituted themselves, at their own expense, for the exercise of a public function (that of making sure that price increases do not put at risk solidarity and other constitutional principles).
「是」字句和「是……的」句的教學語法: 以九套國際學校中文教材為例
Authors: Wing-Yu Tam Hugo 
Published: September 2021

AbstractDue to the economic growth in East and Southeast Asia, the global interest in teaching and learning Asian languages has been continually increasing in the past two decades. More and more international schools are offering Asian languages as elective second/foreign languages to adolescent learners, such as Arabic, modern Chinese (Cantonese/Mandarin), Japanese, and Malay. Since 2008, the most common grammatical mistake,shi(literallyto be) had been highlighted by the Cambridge Assessment every single year in the IGCSE Mandarin (0547) examiner reports. This paper reviews the literature of the functions and the error patterns of copula verbshiand “shi…de” construction, then investigates how the textbooks describe the grammatical usages and sequence the different functions ofshifor young learners. Based on the qualitative research findings, this study proposes suggestions for improving the description of grammar items in Mandarin textbooks, and illustrates the classroom activities and teaching strategies for parts of speech in the international school context. This research has implications for second language acquisition, pedagogical grammar, and teacher education for IGCSE Mandarin.
Language play in and with Chinese: traditional genres and contemporary developments
Authors: Wei Li , Lee Tong King 
Published: September 2021

Abstract
Language play is playing with the rules of language for fun. This article is one of the first attempts at providing an overview of the traditional genres and current trends of language play in and with Chinese, a topic that has received relatively little attention in English. We explore the specific aspects of the Chinese language that are susceptible to play, and discuss a number of conventional formulas of Chinese language play. We also examine the affordances of new media and what we call translanguaging language play that involves mixing different named languages and scripts as well as mixing linguistic with other semiotic resources. The motivations and effects of language play are discussed, giving particular attention to the socio-political dimensions of language play. Throughout the discussion, we provide historical as well as contemporary examples to illustrate the ways in which Chinese language users play with language for specific purposes.