bluuebunny/crossref_metadata_2025_split huggingface dataset:
Target insiders' preferences when trading before takeover announcements: Deal completion probability, premium and deal characteristics
Authors: Fidrmuc Jana P. , Xia Chunling 
Published: March 2021

AbstractWe contribute to the M&A literature by characterizing the information available to target insiders during the pre‐public takeover negotiations. We analyze insider trading in target firms in the US between 2005 and 2018. First, we show that signing confidentiality agreements is an important information threshold. Second, insiders have a good grasp of deal success. They increase their net purchases only in deals with higher completion probability. Third, insiders guess the final offer price well, but their trading strategies additionally reflect their knowledge of deal characteristics. They prefer bidder‐initiated, cash, privately negotiated, and strategic deals. Insiders combine several sources of information.
Association of putatively adaptive genetic variation with climatic variables differs between a parasite and its host
Authors: Walters Sheree J. , Robinson Todd P. , Byrne Margaret , Wardell‐Johnson Grant W. , Nevill Paul 
Published: March 2021

AbstractParasitism is a pervasive phenomenon in nature with the relationship between species driving evolution in both parasite and host. Due to their host‐dependent lifestyle, parasites may adapt to the abiotic environment in ways that differ from their hosts or from free‐living relatives; yet rarely has this been assessed. Here, we test two competing hypotheses related to whether putatively adaptive genetic variation in a specialist mistletoe associates with the same, or different, climatic variables as its host species. We sampled 11 populations of the specialist mistletoe Amyema gibberula var. tatei (n = 154) and 10 populations of its associated host Hakea recurva subsp. recurva (n = 160). Reduced‐representation sequencing was used to obtain genome‐wide markers and putatively adaptive variation detected using genome scan methods. Climate associations were identified using generalized dissimilarity modelling, and these were mapped geographically to visualize the spatial patterns of genetic composition. Our results supported the hypothesis of parasites and host species responding differently to climatic variables. Temperature was relatively more important in predicting allelic turnover in the specialist mistletoe while precipitation was more important for the host. This suggests that parasitic plants and host species may respond differently to selective pressures, potentially as a result of differing nutrient acquisition strategies. Specifically, mistletoes acquire water from hosts (rather than the abiotic environment), which may provide a buffer to precipitation as a selective pressure. This work deepens and complements the physiological and other ecological studies of adaptation and provides a window into the evolutionary processes that underlie previously observed phenomena. Applying these methods to a comparative study in a host–parasite system has also highlighted factors that affect the study of selection pressure on nonmodel organisms, such as differing adaptation rates and lack of reference genomes.
Current carbon prices do not stack up to much land use change, despite bundled ecosystem service co‐benefits
Authors: Summers David M. , Regan Courtney M. , Settre Claire , Connor Jeffery D. , O’Connor Patrick , Abbott Hayley , Frizenschaf Jacqueline , van der Linden Leon , Lowe Andrew , Hogendoorn Katja , Groom Scott , Cavagnaro Timothy R. 
Published: March 2021

AbstractBiological sources of carbon sequestration such as revegetation have been highlighted as important avenues to combat climate change and meet global targets by the global community including the Paris Climate Agreement. However, current and projected carbon prices present a considerable barrier to broad‐scale adoption of tree planting as a key mitigation strategy. One avenue to provide additional economic and environmental incentives to encourage wider adoption of revegetation is the bundling or stacking of additional co‐beneficial ecosystem services that can be realized from tree planting. Using the World's largest land‐based carbon credit trading scheme, the Australian Emissions Reduction Scheme (ERF), we examine the potential for three pairs of ecosystem services, where the carbon sequestration value of land use change is paired with an additional co‐benefit with strong prospects for local tangible benefits to land owners/providers. Two cases consider agricultural provisioning values that can be realized by the landowners in higher returns: increased pollination services and reduced lamb mortality. The third case examined payments for tree plantings along riparian buffers, with payments to farmers by a water utility who realizes the benefit from reduced treatment cost due to water quality improvements. Economic incentives from these co‐benefit case studies were found to be mixed, with avoided treatment costs from water quality paired with carbon payments the most promising, while pollination and reduced lamb mortality paired with carbon payments were unable to bridge the economic gap except under the most optimistic assumptions. We conclude that the economics case for significant land use change are likely to be geographically dispersed and only viable in relatively niche landscape positions in high establishment, high opportunity cost areas even when carbon payments are augmented with the value of co‐benefits classified as providing direct and local benefits.
A regional inter‐disciplinary partnership focusing on the development of a carinata‐centered bioeconomy
Authors: George Sheeja , Seepaul Ramdeo , Geller Dan , Dwivedi Puneet , DiLorenzo Nicolas , Altman Rich , Coppola Ed , Miller Stephen A. , Bennett Rick , Johnston Glenn , Streit Leon , Csonka Steve , Field John , Marois Jim , Wright David , Small Ian M. , Philippidis George P. 
Published: March 2021

AbstractBrassica carinataor Ethiopian mustard, a non‐edible oilseed brassica, is a low carbon, purpose‐grown, and none‐to‐low indirect land‐use change bioenergy feedstock for the production of drop‐in sustainable aviation fuel, biodiesel, renewable diesel, and a suite of value‐added coproducts. Carinata oil converted to drop‐in fuel using an American Society for Testing and Materials approved Catalytic Hydrothermolysis process has been successfully tested in commercial and military aviation. Carinata meal, the residue after oil extraction, is a high‐protein feed supplement for livestock, poultry, and swine, and can also yield specialty products. The Southeast Partnership for Advanced Renewables from Carinata (SPARC) is a public–private partnership formed with a twofold mission: (1) Removing physical, environmental, social, and economic constraints that prevent regional intensification of carinata production as a low‐carbon feedstock for renewable fuel and coproducts and (2) demonstrating enhanced value across the entire value chain by mitigating risk to farmers and other stakeholders. The partnership's goal is to energize the US bioeconomy through sustainable agriculture and thus contribute to energy security and economic diversification. SPARC relies on a combination of cutting‐edge multidisciplinary research and active industry engagement to facilitate adoption of the crop. This involves informing stakeholders along the entire supply chain, from producers to end‐users, policymakers, influencers, and the public, about the opportunities and best practices related to carinata. This article provides context and background concerning carinata commercialization as a winter cash crop in the Southeast US for renewable fuels and bioproducts. The advances made to date in the areas of feedstock development, fuel and coproduct development, meal valorization, supply chain logistics, and stakeholder engagement are outlined.
Opt‐in or opt‐out health‐care communication? A cross‐sectional study
Authors: Tong Vivien , Krass Ines , Robson Stephen , Aslani Parisa 
Published: March 2021

AbstractBackgroundPatients need medication and medical condition‐related information to better self‐manage their health. Health‐care professionals (HCPs) should be able to actively provide information outside of one‐on‐one consultations; however, patient consent may be required.ObjectiveTo investigate the Australian public's preferences, and factors that may influence their preferences, towards an opt‐in versus an opt‐out approach to health communication.DesignA cross‐sectional study using a structured questionnaire administered via Computer‐Assisted Telephone Interviewing.Setting and participantsParticipants across Australia who were adults, English‐speaking and had a long‐term medical condition.Main outcome measuresPreferences for opt‐in vs opt‐out approach to receiving follow‐up tailored information.ResultsA total of 8683 calls were made to achieve the required sample size of 589 completed surveys. Many (346/589; 58.7%) indicated that they were interested in receiving tailored, ongoing follow‐up information from their HCP. Nearly half (n = 281; 47.7%) preferred an opt‐in service and 293/589 (49.7%) an opt‐out service for receiving follow‐up information. Reasons for preferring an opt‐in service were being in control of the information received (n = 254); able to make a decision that is best for them (n = 245); opt‐in service would save time for HCPs (n = 217); they may not want or need the information (n = 240). Many (n = 255) felt that an opt‐out service should be part of the normal duty of care of their HCP and believed (n = 267) that this approach would ensure that everyone has access to information.ConclusionsRespondents were interested in receiving tailored information outside of consultation times. However, preferences for an opt‐in or opt‐out approach were divided.
Approaches to optimize patient and family engagement in hospital planning and improvement: Qualitative interviews
Authors: Anderson Natalie N. , Baker G. Ross , Moody Lesley , Scane Kerseri , Urquhart Robin , Wodchis Walter P. , Gagliardi Anna R. 
Published: March 2021

AbstractBackgroundPatient engagement (PE) in health‐care planning and improvement is a growing practice. We lack evidence‐based guidance for PE, particularly in hospital settings. This study explored how to optimize PE in hospitals.MethodsThis study was based on qualitative interviews with individuals in various roles at hospitals with high PE capacity. We asked how patients were engaged, rationale for approaches chosen and solutions for key challenges. We identified themes using content analysis.ResultsParticipants included 40 patient/family advisors, PE managers, clinicians and executives from 9 hospitals (2 < 100 beds, 4 100 + beds, 3 teaching). Hospitals most frequently employed collaboration (standing committees, project teams), followed by blended approaches (collaboration + consultation), and then consultation (surveys, interviews). Those using collaboration emphasized integrating perspectives into decisions; those using consultation emphasized capturing diverse perspectives. Strategies to support engagement included engaging diverse patients, prioritizing what benefits many, matching patients to projects, training patients and health‐care workers, involving a critical volume of patients, requiring at least one patient for quorum, asking involved patients to review outputs, linking PE with the Board of Directors and championing PE by managers, staff and committee/team chairs.ConclusionThis research generated insight on concrete approaches and strategies that hospitals can use to optimize PE for planning and improvement. On‐going research is needed to understand how to recruit diverse patients and best balance blended consultation/collaboration approaches.Patient or public contributionThree patient research partners with hospital PE experience informed study objectives and interview questions.
Does the drought tolerance of guar [Cyamopsis tetragonoloba (L.) Taub.] extend belowground to root nodules?
Authors: Shrestha Rajan , Adams Curtis B. , Rajan Nithya 
Published: March 2021

AbstractIn cultivating guar [Cyamopsis tetragonoloba (L.) Taub], a drought‐tolerant legume, producers anticipate soil N credits through biological N fixation (BNF), but it has been speculated that root nodulation is poor under dry conditions and little is known about how nodules recover from drought stress. To provide better insight, two greenhouse studies were conducted to investigate static (25%, 50%, 75% and 100% ET replacement in two soils) and dynamic (50%, 75% and 100%, plus 50% and 75% relieved to 100% at 20 and 30 days after planting) water regimes on guar over 50 days. Water stress generally had the greatest negative impact on nodule weight, followed by aboveground biomass, reproductive nodes, height and then nodule number. Parameter responses were either linear or quadratic with ET replacement and response slopes differed between soils for nodule weight and biomass. The relatively minor effect on nodule number indicated the basic machinery for BNF (nodules) remained largely intact until water stress was extreme. This was likely a key factor that enabled strong and rapid recovery of nodule growth following relief of water stress. Biomass recovery was likewise robust, with production equal to the stress‐free control, regardless of the intensity and duration of the stress. These results show that nodule growth in guar is highly sensitive to water stress, but the plant is resilient in maintaining nodules under water stress and recovering nodule growth upon moisture restoration.
Improving predictions of range expansion for invasive species using joint species distribution models and surrogate co‐occurring species
Authors: Briscoe Runquist Ryan D. , Lake Thomas A. , Moeller David A. 
Published: March 2021

AbstractAimsSpecies distribution models (SDMs) are often used to forecast potential distributions of important invasive or rare species. However, situations where models could be the most valuable ecologically or economically, such as for predicting invasion risk, often pose the greatest challenges to SDM building. These challenges include non‐equilibrium range expansion, low or uneven prevalence, and projecting distributions into environments that are non‐analogous to the environments used for model building.LocationMinnesota, USA.TaxonCardamine impatiens (Narrowleaf Bittercress), Celastrus orbiculatus (Oriental Bittersweet), and Humulus japonicus (Japanese Hops).MethodsWe took a novel approach to build robust species distribution models of invasive species using occurrence‐environment correlations between invasive species and co‐occurring native community members. The correlations were obtained from a joint species distribution model (JSDM) of a densely sampled database of 10,336 MN plant communities from across the state of Minnesota, USA. Positively and negatively associated native species were incorporated into the model as surrogate presences and pseudoabsences (weighted by their environmental correlations) along with invasive species occurrences records (surrogate SDMs).ResultsSurrogate models performed better than traditional SDMs in predicting occurrences along the northern invasion margin (outside the training area). Both types of models had similarly high cross‐validation metrics in the area of training. Surrogate models also predicted greater range expansion beyond the current geographic range.Main conclusionsThese results demonstrate that modelers can take advantage of detailed community data to develop SDMs that leverage surrogate native species as phytometers of environments beyond the current area of occupancy. The additional information in surrogate models generates highly effective predictions of invasive species along expanding range margins.
The iatrogenic opioid crisis: An example of ‘institutional corruption of pharmaceuticals’?
Authors: Makhinson Michael , Seshia Shashi S. , Young Gordon Bryan , Smith Preston A. , Stobart Kent , Guha Indra Neil 
Published: March 2021

AbstractRationalePrescribed opioids are major contributors to the international public health opioid crisis. Such widespread iatrogenic harms usually result from collective decision failures of healthcare organizations rather than solely of individual organizations or professionals. Findings from a system‐wide safety analysis of the iatrogenic opioid crisis that includes roles of pertinent healthcare organizations may help avoid or mitigate similar future iatrogenic consequences. In this retrospective exploratory study, we report such an analysis.MethodsThe study population encompassed the entire age spectrum and included those in whom opioids prescribed for chronic pain (unrelated to malignancy) were associated with death or morbidity. Root cause analysis, incorporating recent suggestions for improvement, was used to identify possible contributory factors from the literature. Based on their mandated roles and potential influences to prevent or mitigate the iatrogenic crisis, relevant organizations were grouped and stratified from most to least influential.ResultsThe analysis identified a chain of multiple interrelated causal factors within and between organizations. The most influential organizations were pharmaceutical, political, and drug regulatory; next: experts and their related societies, and publications. Less influential: accreditation, professional licensing and regulatory, academic and healthcare funding bodies. Collectively, their views and decisions influenced prescribing practices of frontline healthcare professionals and advocacy groups. Financial associations between pharmaceutical and most other organizations/groups were common. Ultimately, patients were adversely affected. There was a complex association with psychosocial variables.LimitationsThe analysis suggests associations not causality.ConclusionThe iatrogenic crisis has multiple intricately linked roots. The major catalyst: pervasive pharma‐linked financial conflicts of interest (CoIs) involving most other healthcare organizations. These extensive financial CoIs were likely triggers for a cascade of erroneous decisions and actions that adversely affected patients. The actions and decisions of pharma ranged from unethical to illegal. The iatrogenic opioid crisis may exemplify ‘institutional corruption of pharmaceuticals’.
Description of a new species of Mustura Kottelat (Teleostei: Nemacheilidae) from the Brahmaputra drainage, India
Authors: Choudhury Hrishikesh , Das Rajdeep , Bharali Ratul Ch. , Sarma Kangkan , Tyagi Lalit K. , Lal Kuldeep K. , Sarma Dandadhar 
Published: March 2021

AbstractMustura subhashi, new species, is described from the Dikal River, a north bank tributary of the Brahmaputra drainage in Arunachal Pradesh. It is distinguished from all its congeners by having a colour pattern of 14–23 dark‐greyish black to dark brown irregular bars on a greyish to pale beige body; pre‐dorsal bars thin, numerous, wider than interspaces, weakly contrasted, uniting dorsally at lateral one‐third or midway on flank to form thicker bars, coalescing further at lateral one‐fifth and continuous on dorsum with contralateral bars; bars below dorsal fin exhibiting similar condition but slightly wider than pre‐dorsal bars; post‐dorsal bars thicker than anterior bars, wider than interspaces, sharply contrasted, rarely coalescing on flank; and a short bar along the caudal mid‐line, rarely forming a blotch. Based on re‐examination of the type specimens and additional materials, Mustura dikrongensis is confirmed as a species belonging to Mustura, and M. harkishorei is not sufficiently diagnosed from 'Nemacheilus' corica.
Investigation of time effect on pectin production from citrus wastes with ohmic heating assisted extraction process
Authors: Sabanci Serdal , Çevik Mutlu , Göksu Ali 
Published: March 2021

AbstractPectin is usually extracted by exposure to a high temperature and a specific pH value by conventional methods. However, due to reasons such as low energy efficiency of the process and damage to the pectin, alternative thermal and non‐thermal methods are used in the pectin extraction process. In this study, the effect of different processing times (0, 5, 15, 30, 60, 120, 180 min) on pectin extraction was investigated for grapefruit, lemon, and orange samples at 80°C. Besides, it was determined that the electrical conductivity value ranged between 1.46–2.06 S/m during heating, the electrical conductivity value of the pH solution adjusted with sulfuric acid. Accordingly, it was figured out that the total amount of energy consumed increases as the process holding time increases. However, it was determined that there was a decrease in the average power value by turning on–off the system.Practical ApplicationPectin is one of the additives used in many areas in the food industry. Pectin is now produced especially from agricultural waste peel. During this production, it is subjected to long processes at certain pH and certain temperatures. With the present study, determination of pectin yield over a wide period of time by using ohmic heating process and total ohmic heating energy was determined. In this way, it is thought that a serious contribution will be made to the literature and industry regarding different industrial agricultural waste peel (orange, grapefruit, lemon) during pectin production.
Long‐term symptom severity in people with irritable bowel syndrome following dietetic treatment in primary care: A service evaluation
Authors: Seamark Leah , Barclay Yvonne , Marchant Ceri , Williams Marianne , Hickson Mary 
Published: March 2021

AbstractBackgroundEvidence suggests that dietary interventions can improve symptoms in people with irritable bowel syndrome (IBS), although most data explore the short‐term (immediate) impact. Data on long‐term (>6 months) impact are limited, especially from primary care settings. The present study aimed to investigate the long‐term effect of dietetic‐led interventions for IBS delivered in primary care.MethodsA service evaluation of a dietetic‐led IBS clinic was completed, analysing data on symptom severity, stool frequency and consistency, and healthcare input. Data were collected before and immediately after dietary intervention as part of patients’ routine clinical appointments. Long‐term data were collected via a postal questionnaire at least 11 months later.ResultsIn total, 211 patients responded to the long‐term follow‐up questionnaire at a median of 13 months (interquartile range 12–16 months) post follow‐up appointment. Of these, 84% had been advised to follow a low FODMAP (i.e., fermentable oligosaccharides, disaccharides, monosaccharides and polyols carbohydrates) diet. All symptoms were reported significantly less frequently short term, and all except heartburn and acid regurgitation remained so over the long term. The four most commonly reported bowel symptoms reduced in frequency were abdominal pain (62%), bloating (50%), increased wind (48%) and urgency to open bowels (49%) (p < 0.001). The percentage of patients reporting satisfactory relief of gut symptoms was 10% at baseline and 55% at long‐term follow‐up (p < 0.001). Visits to a general practitioner were reduced (from 96% to 34%; p < 0.001), as were those to the gastroenterologist (from 37% to 12%; p = 0.002), during the year prior to long‐term follow‐up compared to the year prior to dietary intervention.ConclusionsPatients with IBS who received dietetic‐led interventions in primary care reported long‐term symptoms improvements that may result in reduced healthcare usage.