bluuebunny/crossref_metadata_2025_split huggingface dataset:
Disang and Barail Sediments, their Contact and Palaeodepositional Environment along Tuli-Merangkong-Mokokchung Area of Mokokchung District, Nagaland, North East India with Reference to Diverse Palynofossil Assemblages
Authors: Barua Shalini , Kalita Kalpana Deka , Bezbaruah Devojit 
Published: September 2021

Abstract
The contact between the Barail and Disang Group in the belt of Schuppen has been remaining as a controversy amongst the scientists, because the lithologic association of the Nagoan Formation belonging to the Barail Group almost resembles the lithology of the Disang Group. The present study has attempted to establish a contact between the Barail and the Disang in the studied area based on age diagnostic palynomorphs identified and it is observed that the present contact lies about 4.2 km southwest of the established contact by the Directorate of Geology and Mining, Government of Nagaland in 2015. This investigation has documented a diverse palynofossil assemblages comprising of 58 species under 31 genera from the Disang and the Barail groups belonging to Cretaceous - Eocene - Oligocene age that is extending from Tuli –Merangkong- Mokokchung area of Mokokchung district of Nagaland, northeast India. The assemblage is comprised of angiosperm pollen (43%), fungal remains (35%), pteridophytic spores (19%) and gymnosperm pollen (one genus and one species only). The average representation of other palynotaxa are dinoflagellate cysts (1%), marine elements mainly acritarch and foraminiferal test linings (2%). Based on the presence of different palynomorphs two distinct palynozones (I and II) have been suggested. Sediments of Tuli- Merangkong -Mokokchung area are deposited in deltaic to shallow marine environment.
Beneficial Effect of Sodium Nitrite on EEG Ischaemic Markers in Patients with Subarachnoid Haemorrhage
Authors: Luettich Alexander , Franko Edit , Spronk Desiree B. , Lamb Catherine , Corkill Rufus , Patel Jash , Ezra Martyn , Pattinson Kyle T. S. 
Published: September 2021

AbstractSubarachnoid haemorrhage (SAH) is associated with long-term disability, serious reduction in quality of life and significant mortality. Early brain injury (EBI) refers to the pathological changes in cerebral metabolism and blood flow that happen in the first few days after ictus and may lead on to delayed cerebral ischaemia (DCI). A disruption of the nitric oxide (NO) pathway is hypothesised as a key mechanism underlying EBI. A decrease in the alpha-delta power ratio (ADR) of the electroencephalogram has been related to cerebral ischaemia. In an experimental medicine study, we tested the hypothesis that intravenous sodium nitrite, an NO donor, would lead to increases in ADR. We studied 33 patients with acute aneurysmal SAH in the EBI phase. Participants were randomised to either sodium nitrite or saline infusion for 1 h. EEG measurements were taken before the start of and during the infusion. Twenty-eight patients did not develop DCI and five patients developed DCI. In the patients who did not develop DCI, we found an increase in ADR during sodium nitrite versus saline infusion. In the five patients who developed DCI, we did not observe a consistent pattern of ADR changes. We suggest that ADR power changes in response to nitrite infusion reflect a NO-mediated reduction in cerebral ischaemia and increase in perfusion, adding further evidence to the role of the NO pathway in EBI after SAH. Our findings provide the basis for future clinical trials employing NO donors after SAH.
Design and construction of test facility for evaluation of swell packers in cased and open holes
Authors: Pervez Tasneem , Qamar Sayyad Zahid , Akhtar Maaz , Al Kharusi Moosa 
Published: September 2021

AbstractIn the petroleum industry, packers refer to the components/products which are used to isolate one section in a formation from others, or to isolate the outer section of a production tubing from the inner section, which may be a casing or a liner or the wellbore itself. Mechanical packers are installed through some form of tubing movement. Permanent packers are low in cost and provide better seal. Retrievable packers have lower sealing capability but are re-usable after repair, and therefore expensive. More innovative packers made of swellable elastomers are rather new. These elastomers swell when they come in contact with different types of fluids (mostly water and oil). Like a casing, these new packers are lowered to the desired depth and allowed to swell before production or injection operations begin. Various studies have been published about the swelling and mechanical response of these elastomers. However, many questions remain about the sealing performance of swell packers, and their effectiveness in actual wellbores of rough and random profiles. This paper describes the design and development of an experimental unit for performance testing of a mix of inert and swelling elastomer seals under realistic well conditions. Actual swell packers and petroleum tubulars are housed in a concrete block that replicates open-hole and cased-hole wells through layers of varying roughness. This is a one-of-its-kind unit providing full-scale demonstration about the working of swell packers against outer casing or rock formation in a wellbore. It is also a complete testing apparatus to investigate the behavior of swell packers made of fast-swell and medium-swell elastomers, and how they seal off irregular boreholes. This work can provide basic understanding and visual corroboration to petroleum engineers and students, swelling elastomer application developers, and academic and research personnel.
Quantitative trait loci and candidate genes associated with freezing tolerance of winter triticale (× Triticosecale Wittmack)
Authors: Wąsek I. , Dyda M. , Gołębiowska G. , Tyrka M. , Rapacz M. , Szechyńska-Hebda M. , Wędzony M. 
Published: September 2021

Abstract
Freezing tolerance of triticale is a major trait contributing to its winter hardiness. The identification of genomic regions — quantitative trait loci (QTL) and molecular markers associated with freezing tolerance in winter hexaploid triticale — was the aim of this study. For that purpose, a new genetic linkage map was developed for the population of 92 doubled haploid lines derived from ‘Hewo’ × ‘Magnat’ F1 hybrid. Those lines, together with parents were subjected to freezing tolerance test three times during two winter seasons. Plants were grown and cold-hardened under natural fall/winter conditions and then subjected to freezing in controlled conditions. Freezing tolerance was assessed as the plants recovery (REC), the electrolyte leakage (EL) from leaves and chlorophyll fluorescence parameters (JIP) after freezing. Three consistent QTL for several fluorescence parameters, electrolyte leakage, and the percentage of the survived plants were identified with composite interval mapping (CIM) and single marker analysis (SMA). The first locus Qfr.hm-7A.1 explained 9% of variation of both electrolyte leakage and plants recovery after freezing. Two QTL explaining up to 12% of variation in plants recovery and shared by selected chlorophyll fluorescence parameters were found on 4R and 5R chromosomes. Finally, main locus Qchl.hm-5A.1 was detected for chlorophyll fluorescence parameters that explained up to 19.6% of phenotypic variation. The co-located QTL on chromosomes 7A.1, 4R and 5R, clearly indicated physiological and genetic relationship of the plant survival after freezing with the ability to maintain optimal photochemical activity of the photosystem II and preservation of the cell membranes integrity. The genes located in silico within the identified QTL include those encoding BTR1-like protein, transmembrane helix proteins like potassium channel, and phosphoric ester hydrolase involved in response to osmotic stress as well as proteins involved in the regulation of the gene expression, chloroplast RNA processing, and pyrimidine salvage pathway. Additionally, our results confirm that the JIP test is a valuable tool to evaluate freezing tolerance of triticale under unstable winter environments.
The Potential of Power and Biomass-to-X Systems in the Decarbonization Challenge: a Critical Review
Authors: Poluzzi Alessandro , Guandalini Giulio , d’Amore Federico , Romano Matteo C. 
Published: September 2021

Abstract
Purpose of the Review
The scope of this work is to present a critical review of the novel class of plants for the enhanced production of bioproducts in power and biomass-to-X (PBtX) plants, where the excess carbon in the feedstock is converted into a product thanks to the addition of hydrogen from water electrolysis, rather than being vented as CO2.

Recent Findings
The review of the recent literature shows that (i) a significant gain in carbon efficiency can be achieved with this class of plants compared to corresponding biomass-to-X plants; (ii) there is high dependency of the power-to-X efficiency on the efficiency of the electrolysis system and a relatively low dependency on the final product; and (iii) the economic competitivity of PBtX plants is closely associated to the cost of hydrogen (i.e., electrolysis capital cost, electricity cost, and capacity factor) and such systems cannot rely only on green hydrogen from the low expected amounts of excess electricity from intermittent renewables.

Summary
In this work, through a simplified economic analysis, the region of competitiveness of this class of plants compared to other possible uses of biomass has been qualitatively identified. The research gaps mainly lie in the lack of assessments on the design and operating criteria of flexible PBtX plants and of studies providing insights on the value of flexibility for a PBtX plant, when integrated in the electric energy systems of the future.
First Person Account of Returning to Education and Competitive Employment Following Serious Mental Illness
Authors: Pommeranz Matthew , Lawrence Jeffrey , Dark Frances 
Published: September 2021

AbstractEducation and work goals are important for people with serious mental illness. For many these goals remain unmet. Increasingly people with serious mental illness are inspired by the stories of people who have been able to meet the challenges of gaining education and stable employment. Two peer workers describe their personal journeys to stable employment. Both authors note the significance of having someone believe in their potential to work. The benefits of stable employment went beyond finances and included improved self-esteem and an altruistic wish to provide a role model for others recovering from mental illness.Functional recovery from serious mental illness (SMI) especially in terms of completed education and employment goals is suboptimal. The clinical evidence base in enhancing functional recovery is increasingly complemented by the growing evidence base developed by the consumer network and by the rise in prominence of peer workers as a significant adjunctive mental health workforce.
WEClustering: word embeddings based text clustering technique for large datasets
Authors: Mehta Vivek , Bawa Seema , Singh Jasmeet 
Published: September 2021

AbstractA massive amount of textual data now exists in digital repositories in the form of research articles, news articles, reviews, Wikipedia articles, and books, etc. Text clustering is a fundamental data mining technique to perform categorization, topic extraction, and information retrieval. Textual datasets, especially which contain a large number of documents are sparse and have high dimensionality. Hence, traditional clustering techniques such as K-means, Agglomerative clustering, and DBSCAN cannot perform well. In this paper, a clustering technique especially suitable to large text datasets is proposed that overcome these limitations. The proposed technique is based on word embeddings derived from a recent deep learning model named “Bidirectional Encoders Representations using Transformers”. The proposed technique is named as WEClustering. The proposed technique deals with the problem of high dimensionality in an effective manner, hence, more accurate clusters are formed. The technique is validated on several datasets of varying sizes and its performance is compared with other widely used and state of the art clustering techniques. The experimental comparison shows that the proposed clustering technique gives a significant improvement over other techniques as measured by metrics such Purity and Adjusted Rand Index.
Revisiting Adult Playfulness and Relationship Satisfaction: APIM Analyses of Middle-Aged and Older Couples
Authors: Brauer Kay , Sendatzki Rebekka , Scherrer Tiziana , Chick Garry , Proyer René T. 
Published: September 2021

AbstractThere is robust support for the notion that playfulness is important for how people initiate and engage in their romantic relationships. Our study sought to extend the knowledge on associations between four facets of playfulness (Other-directed, Lighthearted, Intellectual, and Whimsical; OLIW) with facets of relationship satisfaction (RS) in 116 middle-to-older age couples (median = 54 and 57 years in women and men). In comparison to younger samples, we found lower expressions in Other-directed playfulness. Using Actor-Partner Interdependence Modelling, we found that (a) older couples showed comparatively higher similarity in the single OLIW facets and their profiles than previously found in younger couples; (b) similarity is again unrelated to RS; and (c) findings on playfulness-RS associations partially replicated, with Other-directed and Whimsical playfulness showing the numerically strongest actor and partner effects, but mainly in women. We discuss the differences in similarity with regard to an attrition effect. Overall, we conclude that playfulness is important in older couples in similar ways as in younger couples.
MARTIAL AND THE DOCTORS: OPHTHALMOLOGY AND UVULECTOMY IN EPIGRAM 10.56
Authors: Bliquez Lawrence J. 
Published: September 2021

AbstractThis short note attempts to shed light on some of the surgical procedures referred to in Martial's epigram 10.56 by consulting pertinent Graeco-Roman medical texts. A fuller understanding of one such intervention (treatment of infected/inflamed uvula) supports Martial's text as transmitted.
The response of alfalfa genotypes to different concentrations of mobile aluminium
Authors: Liatukienė A. , Skuodienė R. 
Published: September 2021

AbstractThe morphological traits of alfalfa under acid soil conditions with different mobile aluminium (Al) concentrations were investigated. The study site was Vėžaičiai Branch of the Lithuanian Research Centre for Agriculture and Forestry, 55°70 N, 21°49 E. The experiment featuring the 30 most Al-tolerant alfalfa accessions (populations and cultivars), determined from laboratory trials was established on a Bathygleyic Dystric Retisol in 2018. In 2019 and 2020, the biological and morphological traits were evaluated: plant regrowth, plant height before flowering, wintering, leafiness, stem thickness, plant vigour, stem density, seed yield and resistance to spring black stem leaf spot. The resistance of alfalfa to mobile Al toxicity was determined using a filter-based screening method of selection cycles C1 and C2. The accessions grown in the soil with mobile Al (20.6–23.4 mg/kg) showed better tolerance to Al toxicity in the cycle C2. The hypocotyl tolerance index of these accessions was better at 8, 16, 32 and 64 mm AlCl3 concentrations in the cycle C2. The correlation analysis showed strong significant positive and negative relationships between the morphological traits. A cluster analysis showed that the accessions, grown in the soil with mobile Al (20.6–23.4 mg/kg) were the most resistant to Al toxicity in the cycle C2. These accessions produced a better seed yield and demonstrated lower values of morphological traits compared to cluster 2. Also, these accessions are considered as tolerant to mobile Al toxicity and might be used as donors in breeding for Al toxicity tolerance.
The impact of the COVID-19 enforced lockdown and fiscal package on the South African economy and environment: a preliminary analysis
Authors: Chitiga-Mabugu Margaret , Henseler Martin , Mabugu Ramos , Maisonnave Helene 
Published: September 2021

AbstractThis paper offers a quantitative assessment of the impacts of the COVID-19 pandemic-induced lockdown and government fiscal plan, containing ‘green’ elements on the economy and the environment of South Africa. The analysis uses a dynamic computable general equilibrium model operationalised using a social accounting matrix coupled with a greenhouse gas balance and emissions data. We find that while the economy is harshly impacted by the pandemic in the short term, the government fiscal package ameliorates and cushions the negative effects on poor households. Importantly, an adaptation of the fiscal package towards a ‘greener’ policy achieves the same economic outcome and reduces unemployment. Carbon dioxide emissions decrease in the short run due to economic slowdown. This improvement persists until 2030. These results can be used as decision support for policy makers on how to orient the post COVID-19 policies to be pro-poor and pro-environment, and thus, ‘build back better and fairer’.
ON OPTIMAL THRESHOLDS FOR PAIRS TRADING IN A ONE-DIMENSIONAL DIFFUSION MODEL
Authors: FUKASAWA MASAAKI , MAEDA HITOMI , SEKINE JUN 
Published: September 2021

AbstractWe study the static maximization of long-term averaged profit, when optimal preset thresholds are determined to describe a pairs trading strategy in a general one-dimensional ergodic diffusion model of a stochastic spread process. An explicit formula for the expected value of a certain first passage time is given, which is used to derive a simple equation for determining the optimal thresholds. Asymptotic arbitrage in the long run of the threshold strategy is observed.
Compression‐Induced Anomalous Subsidence in the Extensional Sedimentary Basin: A Numerical Study From the Pearl River Mouth Basin, Northern South China Sea Margin
Authors: Li Fucheng , Sun Zhen , Ding Weiwei , Yang Hongfeng , Xie Hui , Pang Xiong , Li Hongbo , Zheng Jinyun 
Published: September 2021

AbstractCompressional uplift has long been considered as the basic response to basin inversion. However, significant discrepancies are recently observed in the Pearl River Mouth Basin (PRMB), where anomalous subsidence occurs during the Miocene compression phase. Whether the subsidence is another scenario that is associated with the tectonic inversion under certain circumstances remains unknown. Here we conduct systematic numerical modeling to explore the patterns of rift basin evolution from extension to compression. Our results show that two distinct inversion types develop depending on the stretching degree and tectonic quiescence. A less stretched continental crust would facilitate the uplift of basin center accompanied by erosion during shortening; otherwise, the basin center exhibits anomalous subsidence with abundant sediment accumulation. We further demonstrate that these two contrasting types, consistent with the Miocene evolutionary pathways of the eastern and western PRMB, respectively, are strongly conditioned by the along‐strike variation of stretching degree during extension.
Late Miocene Onset of Tasman Leakage and Southern Hemisphere Supergyre Ushers in Near‐Modern Circulation
Authors: Christensen Beth A. , De Vleeschouwer David , Henderiks Jorijntje , Groeneveld Jeroen , Auer Gerald , Drury Anna Joy , Karatsolis Boris Theofanis , Lyu Jing , Betzler Christian , Eberli Gregor P. , Kroon Dick 
Published: September 2021

AbstractThis study provides a Miocene‐to‐recent history of Tasman Leakage (TL), driving surface‐to‐intermediate waters from the Pacific into the Indian Ocean. TL, in addition to Indonesian ThroughFlow (ITF), constitutes an important part of the Southern Hemisphere Supergyre. Here, we employ deep‐sea benthic δ13C timeseries from the southwestern Pacific and eastern Indian Oceans to identify the history of Tasman Leakage. The δ13C results combined with sedimentary evidence show that an inter‐ocean connection south of Australia existed from 7 Ma onward. A southward shift in Westerlies combined with a northward movement of Australia created the oceanic corridor necessary for Tasman Leakage (between Australia and the sub‐Antarctic Front) at this time. Furthermore, changes in the northern limb of the Supergyre (ITF) are evident in the sedimentary record on Broken Ridge from ∼3 to 2 Ma when Banda Sea intermediate waters started originating from the North Pacific.
A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapy
Authors: Che Li-Heng , Liu Jing-Wen , Huo Jian-Ping , Luo Rong , Xu Rui-Ming , He Cai , Li Yu-Qing , Zhou Ai-Jun , Huang Piao , Chen Yong-Yu , Ni Wen , Zhou Yun-Xia , Liu Yuan-Yuan , Li Hui-Yan , Zhou Rong , Mo Hui , Li Jian-Ming 
Published: September 2021

AbstractMetastasis is the primary cause of cancer-related mortality in colorectal cancer (CRC) patients. How to improve therapeutic options for patients with metastatic CRC is the core question for CRC treatment. However, the complexity and diversity of stromal context of the tumor microenvironment (TME) in liver metastases of CRC have not been fully understood, and the influence of stromal cells on response to chemotherapy is unclear. Here we performed an in-depth analysis of the transcriptional landscape of primary CRC, matched liver metastases and blood at single-cell resolution, and a systematic examination of transcriptional changes and phenotypic alterations of the TME in response to preoperative chemotherapy (PC). Based on 111,292 single-cell transcriptomes, our study reveals that TME of treatment-naïve tumors is characterized by the higher abundance of less-activated B cells and higher heterogeneity of tumor-associated macrophages (TAMs). By contrast, in tumors treated with PC, we found activation of B cells, lower diversity of TAMs with immature and less activated phenotype, lower abundance of both dysfunctional T cells and ECM-remodeling cancer-associated fibroblasts, and an accumulation of myofibroblasts. Our study provides a foundation for future investigation of the cellular mechanisms underlying liver metastasis of CRC and its response to PC, and opens up new possibilities for the development of therapeutic strategies for CRC.
Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors
Authors: Bedoya-Reina O. C. , Li W. , Arceo M. , Plescher M. , Bullova P. , Pui H. , Kaucka M. , Kharchenko P. , Martinsson T. , Holmberg J. , Adameyko I. , Deng Q. , Larsson C. , Juhlin C. C. , Kogner P. , Schlisio S. 
Published: September 2021

AbstractChildhood neuroblastoma has a remarkable variability in outcome. Age at diagnosis is one of the most important prognostic factors, with children less than 1 year old having favorable outcomes. Here we study single-cell and single-nuclei transcriptomes of neuroblastoma with different clinical risk groups and stages, including healthy adrenal gland. We compare tumor cell populations with embryonic mouse sympatho-adrenal derivatives, and post-natal human adrenal gland. We provide evidence that low and high-risk neuroblastoma have different cell identities, representing two disease entities. Low-risk neuroblastoma presents a transcriptome that resembles sympatho- and chromaffin cells, whereas malignant cells enriched in high-risk neuroblastoma resembles a subtype of TRKB+ cholinergic progenitor population identified in human post-natal gland. Analyses of these populations reveal different gene expression programs for worst and better survival in correlation with age at diagnosis. Our findings reveal two cellular identities and a composition of human neuroblastoma tumors reflecting clinical heterogeneity and outcome.