bluuebunny/crossref_metadata_2025_split huggingface dataset:
Depressive symptoms as a mediator between impulsiveness and suicidal ideation among Chinese medical college students
Authors: Zhang Jingxuan , Zhang Xiaolin , Yang Guoyu , Feng Zhengzhi 
Published: April 2021

Abstract
Background: Suicidal ideation is thought to be of high risk for attempts and behaviours. Researches have suggested that depressive symptoms and impulsiveness can affect suicidal ideation, attempts and behaviours independently. But how they work together in influencing suicidal ideation remains unclear. This study is aiming to investigate the reciprocal associations among impulsiveness, depressive symptoms, and suicidal ideation and to confirm the mediating effect of depressive symptoms on impulsiveness and suicidal ideation through cross-sectional and longitudinal analyses.Methods: The Self-rating Depression Scale (SDS), Barratt Impulsiveness Scale 11th version (BIS-11) and Self-rating Idea of Suicide Scale (SIOSS) were applied, as well as a list of demographic information. Multilinear regression and parallel process latent growth curve models were applied to conduct cross-sectional and longitudinal analyses, respectively.Results: (1) Participants with suicidal ideation scored higher in depressive symptoms and impulsiveness than those without suicidal ideation (P<10-5). (2) The three variables and the three dimensions of impulsiveness were significantly reciprocally correlated with each other (P<0.01). (3) For the impulsiveness total score, non-planning, motor and attention, the multilinear regression models fit well (adjusted R2>0.3, SRMR<0.05). Their indirect effects on suicidal ideation through depressive symptoms were all statistically significant (BIS-SDS-SIOSS, indirect effect coefficient=0.557, P<0.001; non-planning-SDS-SIOSS, indirect effect coefficient=0.480, P<0.001; motor-SDS-SIOSS, indirect effect coefficient=0.486, P<0.001; attention-SDS-SIOSS, indirect effect coefficient=0.504, P<0.001). (4) Four parallel process latent growth curve models fit well (RMSEA<0.05). The total indirect effect of impulsiveness on the growth rate of suicidal ideation through the initial level and growth rate of depressive symptoms was significant (indirect effect coefficient=-0.450, P=0.001). The indirect effects of non-planning and attention impulsiveness were -0.336 (P=0.005) and -0.314 (P=0.002), respectively. However, the indirect effect of motor function on the growth rate of suicidal ideation was not significant (coefficient=-0.379, P=0.067).Conclusions: This study mainly revealed that individuals with impulsive personalities might be at higher risk for and experience more rapid changes in suicidal ideation. The effects were indirect and mediated by depressive symptoms. This implies that impulsive personality with depressive symptoms is critical for suicide prevention and needs more attention.
The Network Structure of Resilience among Chinese Female Nursing Students
Authors: Wang Yifei , Wu Lin , Wang Mei , Sizhe Cheng , Yang Zelong , Ren Lei , Liu Xufeng 
Published: April 2021

Abstract
Background: Many nursing students will suffer from serious psychological problem. However, the intervention research on the psychological resilience of nurses is still in the exploratory stage and the efficiency of existing intervention methods remains variable because of limited comprehension of this relevant psychological construct. Therefore this study investigates the network structure of the 10-item Connor-Davidson Resilience Scale (CD-RISC-10) in Chinese female nursing students to provide a novel understanding for resilience and targets for related interventions. Methods: This study was an online cross-sectional study conducted at three medical universities from 21 August 2020 to 25 August 2020. This study adopted the CD-RISC-10, with a total of 776 participants joined in. Network analysis was conducted and the main focus is strength centrality and predictability. Results: Three edges with strongest unregularized partial correlations existed in the final network, such as between item “Able to adapt to change” and item “Can deal with whatever comes”. The items with strongest strength centrality are “Thinks of self as strong person” and “Can achieve goals despite obstacles”. Conclusions: The results may help us to gain a deeper understanding of resilience and provide educational orientation on how to make students more resilient, which may be benefit in challenge overcoming for nursing students.
Evaluation of the association of ERCC2 rs13181 polymorphism with different types of gliomas in patients in Northeast Brazil
Authors: Tavares Cléciton Braga , Campos-Verdes Larysse Cardoso , Lopes-Costa Pedro Vitor , Gomes-Braga Frsancisca das Chagas Sheyla Almeida , Junior Elmo Jesus Nery , Escórcio-Dourado Carla Solange Melo , Santos Alesse Ribeiro , Sousa Emerson Brandao , Pereira Renato Oliveira , Gebrim Luiz Henrique , Silva Benedito Borges da 
Published: April 2021

Abstract
Gliomas are the most common primary tumors of the central nervous system with unclear etiology. However, hereditary factors may play an important role in glioma development, with mutations and single nucleotide polymorphisms (SNPs) being prominent among the genetic changes. This study aimed to evaluate the association of the ERCC2 gene rs13181 variant polymorphism between high- and low-grade gliomas in patients from Brazil’s Northeast region. Samples from glioma patients stored in paraffin blocks were used. DNA extraction was performed using the MagMAX™ FFPE DNA/RNA Ultra kit, and for genotyping, the Taqman assay probe C_3145033_10 corresponding to the SNP rs13181 of the ERCC2 gene was selected. Quantitative and categorical variables were analyzed using the t-test and Fisher’s exact test or Chi-square test (p < 0.05). Patients with low-grade gliomas were younger than those with high-grade gliomas (p = 0.003). Statistically significant differences were not observed in the expression of the GG, GT, and TT genotypes between low- and high-grade gliomas. The ERCC2 rs13181 genotypes found were TT, GG, and GT; however, no difference in the expression between different glioma types was observed.
The Association Between Obstructive Sleep Apnea and Lung Nodule, Carcinoembryonic Antigen
Authors: Zeng Ai-Ming , Chen Li-Da , Zhao Zhi-Wei , Chen Meng-Xue , Huang Jie-Feng , Lai Guo-Xiang , Lin Qi-Chang 
Published: April 2021

Abstract
Purpose: The association between obstructive sleep apnea (OSA) and cancer risks gaining more and more attention. Data on the association between OSA and lung cancer risk are limited. This study is to investigate whether a link exists between Low-dose computed tomography (LDCT) scanning of the chest findings, carcinoembryonic antigen (CEA) and OSA in patients suspected of OSA.Methods: The cross-sectional study included patients aged 18 years or older who underwent continuous nocturnal polysomnography at our sleep center between February 2019 and November 2020. All subjects underwent chest LDCT and CEA. Patients with an apnea-hypopnea index(AHI) of ≥15/h were classified as clinically significant OSA group, whereas patients with an AHI ＜15/h were classified as control group.Results: A total of 277 patients were enrolled in the study. 176 patients were categorized into the OSA group, while 101 patients were categorized into the control group. There is no relationship between any OSA-related parameter and presence of lung nodule or presence of ≥6mm lung nodule in the binary logistic regression analysis. OSA group demonstrated a significant higher value of CEA than control group. Stepwise multiple linear regression analysis showed that lowest O2 saturation(β=-0.256, p＜0.001), smoking status (β=0.156, p=0.007) and age (β=0.153, p=0.008) were independent predictors of elevated CEA. Conclusion: In a group of patients suspected of OSA, we confirmed an independent correlation between nocturnal hypoxia and elevated CEA levels. OSA was not related with presence of pulmonary nodule or≥6 mm pulmonary nodule in LDCT.
Biosafety Assessment of Acinetobacter Strains Isolated From the Three Gorges Reservoir Region in Nematode Caenorhabditis Elegans
Authors: Deng Yunjia , Du Huihui , Tang Mingfeng , Wang Qilong , Huang Qian , He Ying , Cheng Fei , Chen Yu , Xiao Guosheng 
Published: April 2021

Abstract
Acinetobacter is an important nosocomial pathogen frequently detected in backwater areas of the Three Gorges Reservoir (TGR) region. We here employed Caenorhabditis elegans to perform biosafety assessment of Acinetobacter strains isolated from the backwater area in the TGR region and reference strains. Among 21 isolates and 5 reference strains of Acinetobacter, exposure to Acinetobacter strains of AC1, AC15, AC18, AC21, A. baumannii ATCC 19606T, A. junii NH88-14 and A. lwoffii DSM 2403T resulted in significant decrease in locomotion behavior and reduction in lifespan. In nematodes, exposure to Acinetobacter strains of AC1, AC15, AC18, AC21, A. baumannii, A. junii and A. lwoffii also resulted in significant reactive oxygen species (ROS) production. Moreover, exposure to Acinetobacter isolates of AC1, AC15, AC18, and AC21 led to significant increase in expressions of both SOD-3::GFP and some antimicrobial genes (lys-1, spp-12, lys-7, dod-6, spp-1, dod-22, lys-8, and/or F55G11.4) in nematodes. The Acinetobacter isolates of AC1, AC15, AC18, and AC21 had different morphological, biochemical, and phylogenetical properties. Our results suggested that it exists the exposure risk of some Acinetobacter strains isolated from the TGR region for environmental organisms and human health, and Caenorhabditis elegans can be used to assess the biosafety of Acinetobacter isolates from the environment.
Corrosion Behavior of the Nickel/nickel Interface During the Copper Sacrificial Layer Releasing Process in Micro-Electroforming
Authors: Wang Lili , Ye Minheng , Wang Yingying , Tian Dong , Ye zuoyan , Wang Chao 
Published: April 2021

Abstract
The corrosion behavior of the Ni/Ni interface during the Cu sacrificial layer releasing process in micro-electroforming has been investigated. The XPS and SEM results reveal that the pre-existing passive layer and interfacial defects exist on the Ni/Ni interface. Compared with Ni base, the interface is prone to be attacked. Pitting corrosion occurs along interface boundary, which contains three main processes, pit initiation, pit growth and pits fusion, leading to a commensurate reduction in interfacial adhesion strength and ultimately structural integrity. The combination of the substrate modification and heat post treatment is an effective solution to avoid the localized corrosion. We believe that both the surface activation and thermally induced diffusion have worked.
Evaluation of Corneal Endothelium in Middle-Aged Keratoconus Eyes
Authors: Doğan Emine , Çakır Burçin , Aksoy Nilgün , Alagöz Gürsoy 
Published: April 2021

Abstract
Purpose

To investigate the corneal endothelial cell parameters and to evaluate the correlation with corneal topographic parameters in middle-aged non-treated keratoconus (KC) patients.
Materials and Methods

Thirty-six eyes of 21 KC patients in the middle decade (4th-5th) and age-gender matched 36 healthy eyes were included. Topographic parameters [(K1, K2 Sim K, central, thinnest pachymetry, anterior chamber depth (ACD)] were obtained with Galillei double scheimpflug analyzer. Patients were divided into stages according to mean keratometric values ​​(Mild < 45D,Moderate 45-52D, Severe > 52D, Advanced > 62 D). Endothelial cell density (ECD), coefficient of variation (CV) of cell areas and hexagonal cell percentage (HCP) obtained with specular microscopy were recorded.Corneal topography and specular microscopy parameters were compared between KC and healthy eyes. The correlation between topographic and specular microscopy parameters were analyzed.
Results

The mean age of the patients was 38.6 ± 6.0 and 37.8 ± 4.2 years in the KC and control group, respectively. Age and gender were statistically similar between the groups. ECD was 2772 ± 17 in the KC group and 2741 ± 30 cells / mm2 in the control group, and there was no statistical difference between the groups (p: 0.621). HCP was 63.5 ± 7.2, 67.4 ± 5.2 in KC and healthy eyes, respectively (p: 0.014); CV was 30.7 ± 5.2 and 28.6 ± 3.4, respectively (p: 0.058). Specular microscopy parameters were not statistically different according to KC stage. K1,K2,SimK, CCT, ACD did not correlate with ECD in patients.
Conclusion

Our results showed that endothelial cell morphology is significantly affected in middle-aged KC patients who have not been treated.
Association between maternal dietary quality and gestational diabetes mellitus based on the Diet Balance Index for Pregnancy
Authors: Wang Shanshan , Wang Ning , Luo Can , Zhao Rui , Du Yatan , Xie Huihui , Lu Yuxuan , Xu Yue , Wang Dongxia , Li Yan , Yang Xuefeng , Xiong Guoping , Hao Liping 
Published: April 2021

Abstract
Background: Maternal diet is critical to the development of gestational diabetes mellitus (GDM), but sparse studies have applied the Chinese Dietary Balance Index for Pregnancy (DBI-P) to assess the maternal dietary quality and its relationship with GDM. We aimed to examine the maternal dietary quality and its relationship with GDM risk using the newly developed DBI-P. Methods: We included 1122 pregnant women from the Tongji Birth Cohort (TJBC) in Wuhan, China. The semi-quantitative food frequency questionnaire (FFQ) was used to obtain the dietary information during pregnancy. The newly developed DBI-P, including DBI-P components and DBI-P dietary patterns, was applied to comprehensively evaluate the maternal dietary quality. GDM was diagnosed by the 75-g, 2-h oral glucose tolerance test at 24-28 weeks gestation. We used a generalized linear regression model to examine the relationship between DBI-P components and blood glucose levels, and a logistic regression model to examine the relationship between dietary patterns and GDM. Results: A total of 179 participants (16.0%) were diagnosed with GDM. There is a widespread phenomenon of dietary imbalance among pregnant women in Wuhan. With per score increase in nuts and eggs, fasting blood glucose increase by 0.03 mmol/l (95% CI: 0.01, 0.05) and 0.01 mmol/l (95 %CI: 0.01, 0.03), respectively, while per score increase in fruits, 1-h post-load blood glucose decreased by 0.05 mmol/l (95% CI: -0.10, -0.01). Besides, compared with pattern E characterized by higher intake of total energy, total fat, fruits, and cooking oil, pattern B (OR: 0.51, 95% CI: 0.26, 0.99) and pattern C (OR: 0.27, 95% CI: 0.09, 0.81) were associated with a lower GDM risk. The associations between dietary patterns and GDM risk may be partly attributed to the intakes of dietary total fat, carbohydrate, cholesterol, eggs, and cooking oil. Conclusions: Unfavorable dietary quality during pregnancy is associated with a higher risk of GDM. The newly established DBI-P can provide an easy-to-implement tool to assess maternal dietary quality. These findings will provide new insights for the exploration of preferable dietary evaluation methods and prevention and control of GDM.
Confluences and Land Cover As Agents of Change: Temporal Habitat Variability Modifies the Movement and Assemblage Change of Headwater Fishes
Authors: Hubbell Joshua P. , Schaefer Jacob F. 
Published: April 2021

Abstract
Interspersed inputs of wood and sediment brings about morphological change at confluences and the extent to which these processes are modified by anthropogenic disturbance has ramifications for stream fish assemblages. In this study, we use three functional groups of headwater fishes to assess the influences of confluence size and land cover on habitat stability, distance moved, movement rate, and assemblage change in a Gulf Coastal Plain drainage in the southeastern United States using a 2X2 design. Our results suggest that differences in habitat stability were described by a hydrogeomorphic gradient, and urban reaches characterized by a confluence size > 0.6 displayed the greatest habitat instability. Water-column specialists in urban reaches were more likely to move when habitat change was limited, whereas movement by this functional group in forested reaches was more likely in response to greater habitat instability. Therefore, the distance moved by water-column specialists was related to land cover. Assemblage change also occurred at a more constant rate in urban reaches in response to habitat instability. There was little evidence that confluence size influenced movement or assemblage stability in these headwater assemblages. Our understanding of the extent to which land cover alters the geomorphic and ecological gradients associated with headwater confluences will be critical to ensure the conservation of sensitive species whose fitness is dependent on the integrity of these habitats.
Alpha-T: Learning to Traverse over Graphs with An AlphaZero-inspired Self-Play Framework
Authors: Wang Qi 
Published: April 2021

Abstract
The combinatorial optimization problems on the graph are the core and classic problems in artificial intelligence and operations research. For example, the Vehicle Routing Problem (VRP) and Traveling Salesman Problem (TSP) are not only very interesting NP-hard problems but also have important significance for the actual transportation system. Traditional methods such as heuristics methods, precise algorithms, and solution solvers can already find approximate solutions on small-scale graphs. However, they are helpless for large-scale graphs and other problems with similar structures. Moreover, traditional methods often require artificially designed heuristic functions to assist decision-making. In recent years, more and more work has focused on the application of deep learning and reinforcement learning (RL) to learn heuristics, which allows us to learn the internal structure of the graph end-to-end and find the optimal path under the guidance of heuristic rules, but most of these still need manual assistance, and the RL method used has the problems of low sampling efficiency and small searchable space. In this paper, we propose a novel framework (called Alpha-T) based on AlphaZero, which does not require expert experience or label data but is trained through self-play. We divide the learning into two stages: in the first stage we employ graph attention network (GAT) and GRU to learn node representations and memory history trajectories, and in the second stage we employ Monte Carlo tree search (MCTS) and deep RL to search the solution space and train the model.
Application of Business Intelligence (BI) To Nutritional Support for Successful Ventilator Weaning
Authors: Lo Shih-Ching , Li Yan-Ru , Li Zi-Yue , Lin Cheng-Hung , Lin Hsing-Chun 
Published: April 2021

Abstract
The aim of this study was to apply business intelligence (BI) to monitoring of ventilated patient nutritional status to determine appropriate strategies for ventilator weaning.We collected data on patient characteristics, nutrition delivered, and clinical outcomes. From October 2017 to July 2019, 322 ventilated patients were enrolled and divided into successful extubation and failed weaning groups. The mean age was 67.6±16.6 years, 201 patients were men (62.4%) and 121 were women (37.6%). Successful extubation group consisted of patients who underwent surgery (p=0.001), were treated for neurological issue (p=0.002), had higher weight before pre-weaning (p=0.02), and lost weight during the weaning process (p<0.001). Both groups were given the same nutritional intervention initially. Successful extubation group received significantly more calories and protein post-weaning (p=0.022 and 0.006). Successful weaning was associated with higher survival rate (p=0.016), shortened hospital stay (p=0.005), and reduced medical costs (p<0.001).We suggest 28 kcal/kg/day and protein 1.2 g/kg/day to optimize nutrition for successful ventilator weaning.
Detection and Prevention of Drop Attack in WANET Using Robust Scheme Method
Authors: P Vinoth kumar , K Venkatesh 
Published: April 2021

Abstract
Performance and protection are the main important factors of Wireless Ad-hoc Network. Network protection includes the protection, stability and parameters of WANET. This helps to avoid significant service disruptions and increases network productivity by making the network more efficient. Since wireless ad hoc networks lack concentrate network management, these methods are vulnerable to data attack. In selected intruder finding tests, the neighboring locations are not trusted to send messages below. It is important to expose the invalid node, which pulls the capture mode and separates it from the network by pushing its routing mechanism. In this paper, we introduce the Resistant Drop Attack (RDA) method to provide effective protection against data loss. An RDA network protocol is recommended to detect weak nodes in the network during a fixed-speed attack. The RDA protocol can be embedded with present Wireless Ad-hoc Network routing systems such as AODV and DSR. Using the Digital Signature Algorithm (DSA) improves the reliability of the route by blocking links at high speeds and verifying the nodes.
A Hybrid Multi-Dimensional Usability Evaluation Approach Proposal: A Case Study Related to Airline Firms’ Websites
Authors: Can Gülin Feryal , DELİCE Elif KILIÇ 
Published: April 2021

Abstract
This study aims to advance a new multi-dimensional usability evaluation approach (MDUEA) for websites including four phases In the first phase, components of usability evaluation as tasks, participants, usability criteria are determined. In the second phase, the Morae V3 package program used for the tests recording the user actions and the system usability scale (SUS) is performed by Morae at the end of the each task. In the third phase, Preference Selection Index (PSI), ENTROPY and The Criteria Importance through Inter criteria Correlation (CRITIC) are performed to obtain objective usability criteria weights considering a novel three-dimension initial decision matrices than, the weights obtained from these three techniques are aggregated via geometric mean operator. In the same phase, Rank Sum (RS), Rank Reciprocal (RR) and Rank Exponent (RE) methods are utilized to compute subjective criteria weights than, weights obtained from these three approaches are aggregated via using geometric mean operator. In the fourth phase, Combinative Distance-based Assessment (CODAS) is used to rank websites considering a new proposed threshold function value computation for objective criteria group and subjective criteria group separately.
Developmental Changes of The Central Sulcus Morphology In Young Children
Authors: Gajawelli Niharika , Deoni Sean , Ramsey Natalie , III Douglas C Dean , O'Muircheartaigh Jonathan , Nelson Marvin D , Lepore Natasha , Coulon Olivier 
Published: April 2021

Abstract
"The human brain grows rapidly in early childhood, reaching 95% of its final volume by age 6. Understanding brain growth in childhood is important both to answer neuroscience questions about anatomical changes in development, and as a comparison metric for neurological disorders. Metrics for neuroanatomical development including cortical measures pertaining to the sulci can be instrumental in early diagnosis, monitoring and intervention for neurological diseases. In this paper, we examine the development of the central sulcus in children aged 12 to 60 months from structural magnetic resonance images. The central sulcus is one of the earliest sulci to develop at the fetal stage and is implicated in diseases such as Attention Deficit Hyperactive Disorder and Williams syndrome. We investigate the relationship between the changes in the depth of the central sulcus with respect to age. In our results, we observed a pattern of depth present early on, that had been previously observed in adults. Results also reveal the presence of a rightward depth asymmetry at age 12 month at a location related to orofacial movements. That asymmetry disappears gradually, mostly between 12 and 24 months, and we suggest that it is related to the development of language skills."