bluuebunny/crossref_metadata_2025_split huggingface dataset:
The trend of hemoglobin levels in nasopharyngeal cancer patients treated with chemotherapy in low human development index region in Indonesia
Authors: Lestarini I A , Kadriyan H , Sulaksana M A , Firdausy M S A P , Harahap I L , Karuniawati T P , Wedayani N 
Published: April 2021

Abstract
Nasopharyngeal cancer (NPC) is a malignant tumor in the epithelial cell of the nasopharynx. Globally, the incidence was around 80,000 new cases annually or it composed 0.7% of cancer cases in the world. In locally advanced cases, chemotherapy and radiotherapy is a treatment of choice for this cancer. Chemotherapy could be given before the radiotherapy, or simultaneous, or after the radiotherapy. Chemotherapy can affect the hemoglobin levels by inducing a suppressive effect on bone marrow and a toxic effect on erythrocytes. Thus, this study aimed to explore the trend of hemoglobin levels in every cycle of chemotherapy in patients with NPC. This study is a retrospective study with secondary data collection of patients with NPC who received chemotherapy at the West Nusa Tenggara, one of the regions with low human development index (HDI) in Indonesia, during the period 2017-2019. The data obtained were analyzed descriptively and repeated measurement ANOVA test to explore the difference of hemoglobin levels during every cycle of chemotherapy. The results showed a trend of decreasing mean hemoglobin levels in six series of chemotherapy, with p-value = 0.06 on repeated measurement test. There was a trend of decreasing mean haemoglobin levels in patients with nasopharyngeal cancer who received chemotherapy in low HDI region in Indonesia.
Comparison of three digestion methods for determination of selenium in green tea samples using fluorescence spectrometry
Authors: Kamali S R , Tsai C H , Chen C N 
Published: April 2021

Abstract
Various digestions are available for the determination of selenium (Se) in environmental samples. This study aimed to investigate the most effective digestion method for the determination of Se in green tea samples that effective, eco-friendly, and low cost. Samples were digested with three different acid compositions, the aqua regia method (a mixture of nitric acid-hydrochloric acids HNO3-HCl) in a ratio 1:3, only nitric acid HNO3, and reverse aqua regia method (a mixture of nitric acid-hydrochloric acids HNO3-HCl) in a ratio 3:1. Analysis of Se was conducted using fluorescence spectrometry after derivation by 2,3-diamino naphthalene (DAN). The results show that the aqua regia method was the highest fluorescence intensity. It had given a significant fluorescence intensity of 9.0510 a.u. for 2 mL sample, 26.3689 a.u. for 5 mL sample, 54.4308 a.u. for 10 mL sample, respectively. In addition, the aqua regia digestion resulted in the selenium form in the sample has been converted to tetravalent selenium, and there was a silicone compound as precipitation can be found after digestion. The aqua regia method provides a highly effective digestion method for selenium in green tea samples under fluorescence spectroscopic investigation.
Observation of heavy metal hazard on processed frozen escolar (Lepidocybium flavobrunneum) fillets
Authors: Sipahutar Y H , Sumiyanto W , Panjaitan P S T , Sitorus R , Panjaitan T F C , Khaerudin and R 
Published: April 2021

Abstract
Heavy metals are one of the most dangerous hazards of food products. This study aims to determine the processing flow of frozen escolar fish fillets by observing the cold chain process. The research methods are carried out by applying cold chain, as well as testing the quality and safety of raw material and final products. The parameters tested were Total Plate Count (TPC), histamine, heavy metal tests, and observation of the application of Hazard Analysis Critical Control Point (HACCP) at PT. XYZ, as well as descriptive data analysis and heavy metal monitoring observations. The results showed the quality of raw materials and final products organoleptic values of 8, TPC of 5.5 x103 and 5.5x102, histamine of 2.1 ppm and 2.4 ppm, and heavy metals of raw materials (lead 0.057 mg/kg, cadmium 0.011 mg/kg, mercury 0.037 mg/kg - 0.410 mg/kg). PT. XYZ establishes Critical Control Points (CCP) at the stage of receiving raw materials, metal detecting, and packing and labelling. Supervisor and testing of heavy metal mercury are carried out every three months, lead and cadmium are carried out every six months, on raw materials from each supplier enter the company. Sampling for heavy metal testing was carried out on three size groups, namely size 10-20 kg, size 20-30 kg, and size 30 kg. In conclusion, the organoleptic value, TPC, histamine and heavy metal (mercury, lead and cadmium) were in accordance with the standard. This is the result of the application of the international standard HACCP, which ensures the quality of frozen fish fillet to provide food quality and safety for consumers.
Risk factors and characteristics of laryngeal carcinoma in the developing region of Indonesia
Authors: Kadriyan H , Sulaksana M A , Aryani I G A T , Yudhanto D , Yuliyani E A , Harahap I L , Wedayani A A N 
Published: April 2021

Abstract
In developing regions such as West Nusa Tenggara (WNT), Indonesia, industry, transportation, and lifestyle were also developed synergistically. This development will lead to several consequences such as air pollution, traffic, etc. On the other hand, Laryngeal cancer remains the dominant cancer in the head and neck. It is related to environmental factors such as air pollution as well as a smoking habit. Laryngeal cancer is commonly found in the advanced stage. The study aims to know the factors associated with laryngeal cancer occurrence and the characteristics of the diseases. A retrospective study was conducted through medical records exploration in WNT General Hospital from January 1st, 2018 to December 31st, 2019. All patients in this period will be included as a subject. All risk factors and characteristics of patients were recorded, then analyzed descriptively. Nineteenth patients fulfilled the criteria in the study period. Most of them were male, low socio-economic status, and has a smoking habit. The symptom when the patients seeking medical advice were mainly hoarseness and hoarseness with dyspnea. Predominantly, the patients came in late-stage. Furthermore, the most treatment given was the combination of surgery, chemotherapy, and radiotherapy. The main histopathology result was undifferentiated squamous cell carcinoma.
The effect of tamsulosin and dutasteride combination drug therapy on prostate volume in patients with benign prostatic hyperplasia
Authors: Nandana P I , Adipura L R , Rasyid and H 
Published: April 2021

Abstract

Benign prostatic hyperplasia (BPH) is a benign enlargement of the prostatic gland. This study was conducted to measure the improvement of prostate volume after treatment with Tamsulosin and Dutasteride as a combination drug in BPH patient at RSUD Kota Mataram from February 2020 to April 2020. The data were obtained by documenting the medical records of 20 new BPH patients ultrasound before and after 2 months therapy. This study was conducted using a comparative numerical analytical research model. The analysis was carried out by paired T-test in SPSS. A total of 20 medical records observed, the mean age of the study sample was 67.4 years, with the lowest age at 56 years and the oldest were 79 years, and 85% (17) of samples are more than 60 years old. The average prostate volume pre-therapy was 51.71 cc with the lowest volume was 25 cc and the highest volume 118 cc. Average prostate volume post-therapy was 42.38 cc, with the lowest volume was 22 cc and the highest 92 cc. The ratio of prostate volume more than 40 cc at pre-therapy was 50% (10 samples), and after therapy was decreased to 40% (8 samples). There are significant difference in comparison of pre and post-therapy prostate volume.
The comparative analysis of row proportions and the effect on nutrient status maize and soybean intercropping in sandy soil of North Lombok, Indonesia
Authors: Astiko W , Ernawati N M L , Silawibawa I P 
Published: April 2021

Abstract
Competition is the main problem of application intercropping cultivation in sandy soil, such as water absorption, nutrients, sunlight, and growing space. Plant density and distribution are the primary roles to consume nutrient supply in the sandy soil during intercropping. The study was aimed at determining the nutritional status of maize and soybean intercropping in the sandy soil areas of North Lombok, Indonesia. The experiment was performed at Akar-Akar village in Bayan district of North Lombok and was designed with Randomized Block Design and five treatments, i.e., P1 (2 rows of maize + 2 rows of soybean), P2 (3 rows of maize + 2 rows of soybean), P3 (3 rows of maize + 3 rows of soybean), P4 (4 rows of maize + 2 rows of soybean), P5 (4 rows of maize + 3 rows of soybean). Each treatment was replicated three times. The variables observed were the nutritional status of the soil (N-total and P availability) and nutrient uptake (N and P). The result shows that intercropping patterns of 3 rows of maize and soybean (P3) with the addition of 15 tons of cattle manure per hectare and the inoculation of AMF can increase the nutritional status of soil in nitrogen and phosphorus absorption of plants’ nutrients. It is recommended for farmers to obtain high yields using an intercropping pattern of three rows of maize and three rows of soybeans. This research recommended that nutrient improvement can be achieved by intercropping three rows of maize and three rows of soybean. Further research is needed on the response to yields of various varieties of maize and soybean intercropped on sandy soil.
Developing porang agribusiness for multiple stakeholder benefits and supporting sustainable development in dryland areas of Lombok
Authors: Sjah T , Halil  , Budastra I , Tanaya I G L P 
Published: April 2021

Abstract
Lombok Island, including its dryland area, has a high potential for developing many kinds of crops, not excluded porang (elephant foot yam). This study describes the development of porang agribusiness in Lombok, its opportunities, and ways to develop forward. This study uses several sources of data and several data collection methods, in a term called triangulation. Primary data were collected through interviews guided by the instrument of unstructured questions listed as topics of investigations. Secondary data collection capitalize on available data from individuals and bodies. Data were analyzed mainly using descriptive statistics and qualitative evaluation. Results of the study evidenced several points. Porang is one of the promising crops to be developed in the dryland of Lombok Island. It grows easily and is adaptable to many agricultural conditions. It has also high demand in several forms of products. The consequences that follow from these are that the development of this crop can benefit not only porang growers, but also others, including traders, workers, or regional economic development as a whole. Above all, given that porang grows better with shades, then it brings implications for conserving nature better than that without porang, to add to the benefits of economic and social. This study recommends developing porang in dryland of Lombok or other regions.
The suitability of seagrass ecological function for the survival of the bivalvia on the East Coast of Lombok, Indonesia
Authors: Syukur A , Hidayati B N , Idrus A , Zulkifli L 
Published: April 2021

Abstract
The presence of seagrass in coastal waters has an ecological contribution to marine life’s sustainability, such as bivalves. This study aims to assess the structurer bivalves communities associated with seagrass and the relationship between seagrass communities’ structure and the environment against an abundance of bivalves—the Collected data using transect lines and squares. The data analysis used descriptive statistical analysis. Besides, a regression analysis was carried out between the seagrass community’s structure and its environment with the abundance of bivalves. This study found 40 species of bivalves that include 11 families (Veneroidae, Arcidae, Mytilidae, Cardidae, Pinnadae, Pteriidae, Mactridae, Donacidae, Pectinidae, Tellinidae, and Lucinidae). The next, Anadara antiquata has an abundance of top 1.43 ind/m2, and Atrina vexillum, chlamys luculenta, and Fragum unedo are the lowest of 0.003 ind/ m2. Simultaneously, the analysis results showed that the value of R 2 = 0.42 between the abundance of bivalves with the substrate’s depth. Values are different between seagrass closing with a lot of bivalves, wherein R 2 = 0.80. However, R 2 = 0.36’s value between the abundance of bivalves with a density of seagrass. Of the three parameters, the closure of seagrass is a parameter that can be used to identify the wealth of bivalves’ wealth in the location of the study.
Evaluation of dietary antioxidant intake of school-age children in gold mining area Sekotong, West Lombok, Indonesia
Authors: Ekawanti A , Priyambodo S , Irawati D , Cholidah R 
Published: April 2021

Abstract
Inorganic mercury from artisanal small-scale gold mining had the potency to be free radicals in the human body. Cellular antioxidants e.g. SOD, glutathione, and other antioxidants had an important role in scavenging these free radicals. Dietary antioxidants provided cellular antioxidants. The objective of this study was to identify the dietary antioxidant intake of school-age children in the ASGM area. This study design was cross-sectional and was conducted in the ASGM area of Sekotong subdistrict. Dietary intake of antioxidants was revealed by using 24-hours food recall. The subjects were school-age children in the ASGM area which fulfilled inclusion criteria, namely resided in Sekotong for more than six months, children did not conduct certain diet such as vegetarian. 71s children were enrolled and were inhabitants in 3 villages in Sekotong. 24-hours food recall analyzed using software nutrisurvey and compared to recommended daily allowance. The mean age of the subjects was 9.7 years old, and 60.6 % was female. Mean intake of dietary antioxidants for vitamin A was 566.86 µg, vitamin E was 0.99 mg, vitamin C was 29.81 mg, Zinc 2.42 mg, Copper 0.94 mg, Mangan 1.57 mg, cysteine 0.385 g, and also dietary fiber 3.19 g. All dietary antioxidants did not meet the Recommended Daily Allowance.
Antioxidant activity of brown macroalgae Sargassum ethanol extract from Lombok coast, Indonesia
Authors: Prasedya E S , Martyasari N W R , Abidin A S , Ilhami B T K , Padmi H , Widyastuti S , Sunarwidhi A L , Sunarpi H 
Published: April 2021

Abstract
The coastal areas of Lombok has very high diversity of macroalgae which are largely unexplored. Among them are the brown macroalgae Sargassum species which are well known for their biological potentials. In this study, we aim to evaluate 4 Sargassum species, S.cristaefolium, S. crassifolium, S. polycystum, and S. aquifolium for their antioxidant potential of Sargassum species found the west coastal Aare of Lombok, Indonesia. To determine the antioxidant capacity of macroalgal extracts, 2,2-diphenyl-1-picrylhydrazyl (DPPH) as well as total phenolic content (TPC) were measured. Extracts of the brown macroalgae are well known to have very active antioxidant activity. Among them S. cristaefolium and S.crassifolium provide stronger antioxidant activity compared to S.aquifolium and S.polycystum. Furthermore, correlations were found between TPC macroalgal and their DPPH scavenging activity. This indicates an important role of polyphenols as antioxidants. Overall, brown macroalgae from Lombok coastal area may be a good source of natural bioactive compounds.
The use of a very small business-scale oven to enhance quality of “ready–to-eat” Beef Jerky
Authors: Handayani B R , Widyastuti S , Kertanegara  , Hidayati A , Werdiningsih W , Rahayu T I 
Published: April 2021

Abstract
The aim of this study was to enhance the quality of traditional ready-to-eat beef jerky using a very small business scale (VSB) oven “Rob-Han” 12 racks. The experiment was designed in a Completely Randomized Design consisted of 6 roasting treatments using a laboratory oven (15 min.) and using a Rob Han oven at 5 various times (0, 5, 10, 15, and 20 min.). The results showed that the use of the oven (Rob-Han) significantly affected the chemical qualities of beef jerky i.e. relative humidity, water activity, water content, and protein content. However, the treatments did not significantly affect the ash content of beef jerky. All of the heating time treatments in the oven (Rob-Han) were able to reduce total microbes 2 log cycles (into less than 1,0x103 CFU/gram). Furthermore, coliform and fungi were undetected on agar media of all treatments, therefore they were safe for consumption. Based on the qualities and shelf-life parameters, the best treatment was the roasting for 20 minutes at 135 °C using the oven (Rob-Han) 12 rack, which resulted in beef jerky with a quality similar to that produced by roasting in the laboratory scale oven Memmert.
Implementation of CITES 1973 in Indonesia: a study of shark fishing in Tanjung Luar East Lombok, West Nusa Tenggara
Authors: Nurbani E S , Koynja J J , Pitaloka D , Zunnuraeni  , Octavia D G R 
Published: April 2021

Abstract
This research is based on the issue of sharks being caught by the fishermen at Tanjung Luar, East Lombok. According to an international agreement on the protection of endangered species and Indonesia’s national law, the activity of shark-catching should be limited or even prohibited. Nowadays, sharks as the top predator in the ocean are in the critical condition. Therefore, slow propagation, the limited number of babyshark, and long life cycle, makes them vulnerable against exploitation. This study aims to further investigate on Indonesia’s obligation based on international and national law related to the protection and conservation of sea natural resources, on which shark fishing is the primary case. In principle, this research is normative-legal research. The empirical research onducted by interview and observation are intended to complete the primary data. As the biggest archipelago state, Indonesia is obliged to obey its obligations under international law. The loss or damage of certain species, in this case, the shark in Indonesia will be affecting the global situation. However, the efforts to supervising the shark sale in Tanjung Luar should be the main concern for both local and central government.
In vitro anthelmintic activities of shrub plants extracts for Haemonchus contortus worms
Authors: Hadi R F , Handayanta E , Widyawati S D , Hanifa A , Suprayogi W P S , Sudiyono and 
Published: April 2021

Abstract
This study was conducted to evaluate the anthelmintic activity and effectiveness of shrubs as forage containing tannins as anti-parasites in the digestive tract of small ruminants by in vitro. The types of shrubs used in the study included anting-anting (Acalypha australis linn), bandotan (Ageratum conyzoides), som jawa (Talinum paniculatum), suruhan (Peperomia pellucid L.), and tapak liman (Elephantopus scaber). This study at P0: aquadest (negative control) P1: 10% concentration level of shrubs; P2: 20% concentration level of shrubs, and P3: albendazole 100% (positive control) after 60 minutes of time. The methods of Haemonchus contortus adult worm mortality test were used to investigate the inhibiting effect of in vitro worm mortality from shrub plant extracts. The results of this study on in vitro screening of adult worms, at an increasing concentration, the number of worms that died was significantly more (P <0.05). The highest worm mortality was seen at the concentration level of tapak liman leaf extract (Elephantopus scaber) as much as 20% with a tannin content of 8.89% so that the anthelmintic potential was seen in adult worm mortality. From this study, it can be concluded that the extract of shrubs shows significant anthelmintic activity against the death of adult female Haemonchus contortus worms so that it has the potential to play a role in parasite control in the digestive tract of small ruminants.
Assessment of grouper and snapper fisheries with EAFM approach and sustainable strategy management in Sumbawa-Indonesia
Authors: Hilyana Sitti , Gigentika Soraya , Tezar Rafandi M. , Hernawati  
Published: April 2021

Abstract
The utilization of grouper and snapper resources in Teluk Cempi, Teluk Waworada and the waters of Sape has not been carried out in a sustainable manner, so it is feared that it will interfere with stock availability and the sustainability of grouper and snapper fishery resources. This study aims to assess the status of management and policy strategies for sustainable grouper and snapper fisheries resource management. The data was collected by using a structured interview technique using a questionnaire, Focus Group Discussion, and public consultation. Analysis of the status of grouper and snapper fisheries resources using the Ecosystem Approach to Fisheries Management (EAFM) indicator. The results showed that the condition of grouper and snapper fisheries management is classified as “Less” with an aggregate score 39.6. Sustainable grouper and snapper fisheries management strategies can be carried out through several efforts, including: regulating the allowable quota and fishing time, arrangement of fishing gear, development of artificial coral reef technology and mangrove rehabilitation controlling water quality, optimizing the use of selective fishing gear, livelihood alternatives, management working groups, development for facilities and infrastructure for fisheries supervisors and strengthen institutions (Pokmaswas), knowledge, attitude and practices assistance to fishing communities and formulation of management plan.
A discharge estimation model using a spatial correlation method in Cipanunjang-Cileunca Reservoir, Bandung District, West Java Province
Authors: Marselina Mariana , Sabar Arwin 
Published: April 2021

AbstractCipanunjang-Cileunca reservoir is one of the raw water sources for the Drinking Water Supply System of Bandung City and Bandung District. The total raw water need for both area is 1.66 m3/s. It is known that discharge data estimation is essential for the successful management of the reservoir. This study estimate the future discharge of the Cipanunjang-Cileunca Reservoir using a spatial correlation method, also known as the continuous method. Before the discharge was estimated, the mainstay discharge was first calculated in each reservoir. We found that the mainstay discharge for the raw water in Cipanunjang Reservoir was 0.86 m3/s, while in Cileunca Reservoir was 0.34 m3/s. This study also calculated the sufficient reservoir volume using discharge data from 2000 to 2017, and found that there was a decrease of reservoir volume: from 22 million m3to 18.7 million m3at Cipanunjang Reservoir, and from 11 million m3to 9.5 million m3at Cileunca Reservoir. Discharge estimation using a continuous method showed a correlation between historic discharges, which was 0.87 for Cipanunjang Reservoir and 0.83 for Cileunca Reservoir. This shows that the discharge estimation model using a continuous method, which had a value close to 1, could estimate future discharge.