bluuebunny/crossref_metadata_2025_split huggingface dataset:
Presuppositions, implicatures, and contextual equivalence
Authors: Marty Paul , Romoli Jacopo 
Published: April 2021

AbstractMaximize Presupposition!(MP), as originally proposed in Heim (Semantik: Ein internationales Handbuch der zeitgenössischen Forschung, pp. 487–535, 1991) and developed in subsequent works, offers an account of the otherwise mysterious unassertability of a variety of sentences. At the core of MP is the idea that speakers are urged to use a sentenceψover a sentenceϕifψcontributes the same new information asϕ, yet carries a stronger presupposition. While MP has been refined in many ways throughout the years, most (if not all) of its formulations have retained this characterisation of the MP-competition. Recently, however, the empirical adequacy of this characterisation has been questioned in light of certain newly discovered cases that are infelicitous, despite meeting MP-competition conditions. This has led some researchers to broaden the scope of MP, extending it to competition between sentences which are not contextually equivalent (Spector and Sudo in Linguistics and Philosophy 40(5):473–517, 2017) and whose presuppositions are not satisfied in the context (Anvari in Proceedings of Semantics and Linguistic Theory 28, pp. 711–726, 2018; Manuscript, IJN-ENS, 2019). In this paper, we present a body of evidence showing that these formulations of MP are sometimes too liberal, sometimes too restrictive: they overgenerate infelicity for a variety of felicitous cases while leaving the infelicity of minimally different cases unaccounted for. We propose an alternative, implicature-based approach stemming from Magri (PhD dissertation, MIT, 2009), Meyer (PhD dissertation, MIT, 2013), and Marty (PhD dissertation, MIT, 2017), which reintroduces contextual equivalence and presupposition satisfaction in some form through the notion of relevance. This approach is shown to account for the classical and most of the novel cases. Yet some of the latter remain problematic for this approach as well. We end the paper with a systematic comparison of the different approaches to MP and MP-like phenomena, covering both the classical and the novel cases. All in all, the issue of how to properly restrict the competition for MP-like phenomena remains an important challenge for all accounts in the literature.
Eisenstein series and an asymptotic for the K-Bessel function
Authors: Tseng Jimmy 
Published: April 2021

AbstractWe produce an estimate for theK-Bessel function$$K_{r + i t}(y)$$Kr+it(y)with positive, real argumentyand of large complex order$$r+it$$r+itwhereris bounded and$$t = y \sin \theta $$t=ysinθfor a fixed parameter$$0\le \theta \le \pi /2$$0≤θ≤π/2or$$t= y \cosh \mu $$t=ycoshμfor a fixed parameter$$\mu >0$$μ>0. In particular, we compute the dominant term of the asymptotic expansion of$$K_{r + i t}(y)$$Kr+it(y)as$$y \rightarrow \infty $$y→∞. Whentandyare close (or equal), we also give a uniform estimate. As an application of these estimates, we give bounds on the weight-zero (real-analytic) Eisenstein series$$E_0^{(j)}(z, r+it)$$E0(j)(z,r+it)for each inequivalent cusp$$\kappa _j$$κjwhen$$1/2 \le r \le 3/2$$1/2≤r≤3/2.
Anticoagulant treatment satisfaction with warfarin and direct oral anticoagulants for venous thromboembolism
Authors: Fang Margaret C. , Go Alan S. , Prasad Priya A. , Hsu Jin-Wen , Fan Dongjie , Portugal Cecilia , Sung Sue Hee , Reynolds Kristi 
Published: April 2021

AbstractTreatment options for patients with venous thromboembolism (VTE) include warfarin and direct oral anticoagulants (DOACs). Although DOACs are easier to administer than warfarin and do not require routine laboratory monitoring, few studies have directly assessed whether patients are more satisfied with DOACs. We surveyed adults from two large integrated health systems taking DOACs or warfarin for incident VTE occurring between January 1, 2015 and June 30, 2018. Treatment satisfaction was assessed using the validated Anti-Clot Treatment Scale (ACTS), divided into the ACTS Burdens and ACTS Benefits scores; higher scores indicate greater satisfaction. Mean treatment satisfaction was compared using multivariable linear regression, adjusting for patient demographic and clinical characteristics. The effect size of the difference in means was calculated using a Cohen’s d (0.20 is considered a small effect and ≥ 0.80 is considered large). We surveyed 2217 patients, 969 taking DOACs and 1248 taking warfarin at the time of survey. Thirty-one point five percent of the cohort was aged ≥ 75 years and 43.1% were women. DOAC users were on average more satisfied with anticoagulant treatment, with higher adjusted mean ACTS Burdens (50.18 v. 48.01, p < 0.0001) and ACTS Benefits scores (10.21 v. 9.84, p = 0.046) for DOACs vs. warfarin, respectively. The magnitude of the difference was small (Cohen’s d of 0.29 for ACTS Burdens and 0.12 for ACTS Benefits). Patients taking DOACs for venous thromboembolism were on average more satisfied with anticoagulant treatment than were warfarin users, although the magnitude of the difference was small.
Sharing is caring - the importance of capital goods when assessing environmental impacts from private and shared laundry systems in Sweden
Authors: Klint Erik , Peters Gregory 
Published: April 2021

AbstractPurposePrevious studies on environmental impacts from domestic laundry have tended to focus solely on private washing machines and detergent. However, public procurement guidelines about the construction of laundry spaces may also be important. This article aims to expand the scope of previous work so that it also includes tumble drying and the building space. By doing this, we examine the potential for shared systems (which are common in Sweden) to reduce the environmental impacts of laundry activities, in comparison with consumer choices associated with machine operation (i.e., wash temperature and amount of detergent).MethodsAn LCA model was created using product information data from the European Union. Emissions from building use were taken from Swedish cradle-to-grave reports on energy-efficient buildings. The resulting model was run with additional sensitivity analysis of the variables, and the associated emissions from each of the scenarios were calculated.Results and discussionOn average, greenhouse gas (GHG) emissions for private laundries in Sweden were estimated to be 190 g CO2eq./kg laundry (washed and dried). If a shared laundry was used instead, the resulting emissions decreased by approximately 26%. The greatest contribution to GHG emissions was the use of detergent (22–33% of total emissions), followed by capital goods (11–38% of total emissions).ConclusionDeciding to construct shared laundries in newly built apartment buildings in Sweden, rather than in-unit machines, would reduce the emissions from domestic laundry for these tenants by approximately 26%. This is because materials used for manufacturing whitegoods, as well as the emissions associated with the building itself, play a much bigger role than previously thought. Additionally, since the cleaning efficiency of warm water and some of the components used in detergents rises with temperature, emissions from domestic laundering could for some consumers be reduced further by washing athighertemperature but with less detergent. This pattern could be seen in Sweden within regions with hard water, where the emissions from domestic laundry could be reduced by 6–12%.
Grounding, Essence, and Contingentism
Authors: Lenart Karol 
Published: April 2021

AbstractAccording to grounding necessitarianism if some facts ground another fact, then the obtaining of the former necessitates the latter. Proponents of grounding contingentism argue against this claim, stating that it is possible for the former facts to obtain without necessitating the latter. In this article I discuss a recent argument from restricted accidental generalisations provided by contingentists that advances such possibility. I argue that grounding necessitarianism can be defended against it. To achieve this aim, I postulate a relationship between grounding and essence by introducing a notion of individual essences understood as a set of essential properties that individuate its bearer. According to a proposed view grounding holds in virtue of identities of its relata, which are in turn determined by their respective individual essences. From there I claim that if grounding holds in virtue of the individual essences of its relata, then it is possible to resist the objection from restricted accidental generalisations and maintain a view that grounds necessitates what is grounded.
Visual display for surgical targeting: concepts and usability study
Authors: Regodić Milovan , Bárdosi Zoltán , Diakov Georgi , Galijašević Malik , Freyschlag Christian F. , Freysinger Wolfgang 
Published: April 2021

Abstract
Purpose
Interactive image-guided surgery technologies enable accurate target localization while preserving critical nearby structures in many surgical interventions. Current state-of-the-art interfaces largely employ traditional anatomical cross-sectional views or augmented reality environments to present the actual spatial location of the surgical instrument in preoperatively acquired images. This work proposes an alternative, simple, minimalistic visual interface intended to assist during real-time surgical target localization.

Methods
The estimated 3D pose of the interventional instruments and their positional uncertainty are intuitively presented in a visual interface with respect to the target point. A usability study with multidisciplinary participants evaluates the proposed interface projected in surgical microscope oculars against cross-sectional views. The latter was presented on a screen both stand-alone and combined with the proposed interface. The instruments were electromagnetically navigated in phantoms.

Results
The usability study demonstrated that the participants were able to detect invisible targets marked in phantom imagery with significant enhancements for localization accuracy and duration time. Clinically experienced users reached the targets with shorter trajectories. The stand-alone and multi-modal versions of the proposed interface outperformed cross-sectional views-only navigation in both quantitative and qualitative evaluations.

Conclusion
The results and participants’ feedback indicate potential to accurately navigate users toward the target with less distraction and workload. An ongoing study evaluates the proposed system in a preclinical setting for auditory brainstem implantation.
Predicting regenerative chatter in milling with hardware-in-the-loop simulation using a dexel-based cutting model
Authors: Röck Sascha 
Published: April 2021

AbstractThis article proposes a new model for simulating the interaction between cutting process and machine tool in real-time. The purpose of the model is to be coupled with a real CNC (by using hardware-in-the-loop simulation) in order to consider process forces and to predict regenerative chatter vibrations during virtual commissioning. Therefore a dexel-based workpiece model with adaptive resolution is used for the computation of the chip thickness respectively the cutting forces based on the actual machine tool position and the machining progress on the workpiece. Several simulation experiments are performed to validate the model and to analyze its numerical limits, such as computational accuracy and efficiency. The capability of the model to predict chatter is proven by comparing the simulated critical depth of cut with an analytical solution of the stability lobes. Therefore the dynamics of the machine tool were approximated as a single degree of freedom (SDOF) oscillator. A concluding analysis of the real-time factor confirms the model’s ability to be integrated under hard real-time requirements and with cycle times of just a few milliseconds which are typical of CNCs.
Machine learning and deep learning
Authors: Janiesch Christian , Zschech Patrick , Heinrich Kai 
Published: April 2021

AbstractToday, intelligent systems that offer artificial intelligence capabilities often rely on machine learning. Machine learning describes the capacity of systems to learn from problem-specific training data to automate the process of analytical model building and solve associated tasks. Deep learning is a machine learning concept based on artificial neural networks. For many applications, deep learning models outperform shallow machine learning models and traditional data analysis approaches. In this article, we summarize the fundamentals of machine learning and deep learning to generate a broader understanding of the methodical underpinning of current intelligent systems. In particular, we provide a conceptual distinction between relevant terms and concepts, explain the process of automated analytical model building through machine learning and deep learning, and discuss the challenges that arise when implementing such intelligent systems in the field of electronic markets and networked business. These naturally go beyond technological aspects and highlight issues in human-machine interaction and artificial intelligence servitization.
LINGO-1 shRNA protects the brain against ischemia/reperfusion injury by inhibiting the activation of NF-κB and JAK2/STAT3
Authors: Zhu Jiaying , Zhu Zhu , Ren Yipin , Dong Yukang , Li Yaqi , Yang Xiulin 
Published: April 2021

AbstractLINGO-1 may be involved in the pathogenesis of cerebral ischemia. However, its biological function and underlying molecular mechanism in cerebral ischemia remain to be further defined. In our study, middle cerebral artery occlusion/reperfusion (MACO/R) mice model and HT22 cell oxygen–glucose deprivation/reperfusion (OGD/R) were established to simulate the pathological process of cerebral ischemia in vivo and in vitro and to detect the relevant mechanism. We found that LINGO-1 mRNA and protein were upregulated in mice and cell models. Down-regulation LINGO-1 improved the neurological symptoms and reduced pathological changes and the infarct size of the mice after MACO/R. In addition, LINGO-1 interference alleviated apoptosis and promoted cell proliferation in HT22 of OGD/R. Moreover, down-regulation of LINGO-1 proved to inhibit nuclear translocation of p-NF-κB and reduce the expression level of p-JAK2 and p-STAT3. In conclusion, our data suggest that shLINGO-1 attenuated ischemic injury by negatively regulating NF-KB and JAK2/STAT3 pathways, highlighting a novel therapeutic target for ischemic stroke.
Identification of robust retailing location patterns with complex network approaches
Authors: Sánchez-Saiz Rosa María , Ahedo Virginia , Santos José Ignacio , Gómez Sergio , Galán José Manuel 
Published: April 2021

AbstractThe problem of location is the cornerstone of strategic decisions in retail management. This decision is usually complex and multidimensional. One of the most relevant success factors is an adequate balanced tenancy, i.e., a complementary ecosystem of retail stores in the surroundings, both in planned and unplanned areas. In this paper, we use network theory to analyze the commercial spatial interactions in all the cities of Castile and Leon (an autonomous community in north-western Spain), Madrid, and Barcelona. Our approach encompasses different proposals both for the definition of the interaction networks and for their subsequent analyses. These methodologies can be used as pre-processing tools to capture features that formalize the relational dimension for location recommendation systems. Our results unveil the retail structure of different urban areas and enable a meaningful comparison between cities and methodologies. In addition, by means of consensus techniques, we identify a robust core of commercial relationships, independent of the particularities of each city, and thus help to distinguish transferable knowledge between cities. The results also suggest greater specialization of commercial space with city size.
Nitration of Jharia basin coals, India: a study of structural modifications by XRD and FTIR techniques
Authors: Boral Prabal , Varma Atul K. , Maity Sudip 
Published: April 2021

AbstractFour coal samples from Jharia basin, India are treated with nitric acid in glacial acetic acid and aqueous media to find out the chemical, petrographic and spatial structure of the organic mass by X-ray diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FTIR) techniques. X-ray parameters of coal like interlayer spacing (d002), crystallite size (Lc), aroamticity (fa), average number of aromatic layers (Nc), and coal rank (I26/I20) have been determined using profile-fitting software. Considerable variation is observed in treated coals in comparison to the demineralized coals. Thed002values of treated coals have increased in both the media showing increase in disordering of organic moieties. A linear relationship has been observed betweend002values with the volatile matter of the coals. Similarly, thed002values show linear relationship with Cdmfcontents for demineralized as well as for the treated coals in both the media. TheLcandNcvalues have decreased in treated coals corresponding to demineralized coals. The present study shows that nitration in both the media is capable of removing the aliphatic side chains from the coals and aromaticity (fa) increases with increase in rank and shows a linear relationship with the vitrinite reflectance. The correspondingI26/I20values are least for treated coals in glacial acetic acid medium followed by raw and then to treated coals in aqueous medium. FTIR studies show that coal arenes of the raw coals are converted into nitro-arenes in structurally modified coals (SMCs) in both the media, the corresponding bands at 1550–1490 and 1355–1315 cm−1respectively. FTIR study confirms that nitration is the predominant phenomenon, though, oxidation and nitration phenomena takes place simultaneously during treatment with nitric acid to form SMCs. In comparison to raw coals, the SMCs show higher aromaticity and may be easily converted to coal derived products like activated carbon and specialty carbon materials.
Measuring diversity from space: a global view of the free and open source rasterdiv R package under a coding perspective
Authors: Thouverai Elisa , Marcantonio Matteo , Bacaro Giovanni , Re Daniele Da , Iannacito Martina , Marchetto Elisa , Ricotta Carlo , Tattoni Clara , Vicario Saverio , Rocchini Duccio 
Published: April 2021

AbstractThe variation of species diversity over space and time has been widely recognised as a key challenge in ecology. However, measuring species diversity over large areas might be difficult for logistic reasons related to both time and cost savings for sampling, as well as accessibility of remote ecosystems. In this paper, we present a new package - - to calculate diversity indices based on remotely sensed data, by discussing the theory behind the developed algorithms. Obviously, measures of diversity from space should not be viewed as a replacement of in situ data on biological diversity, but they are rather complementary to existing data and approaches. In practice, they integrate available information of Earth surface properties, including aspects of functional (structural, biophysical and biochemical), taxonomic, phylogenetic and genetic diversity. Making use of the package can result useful in making multiple calculations based on reproducible open source algorithms, robustly rooted in Information Theory.
Revisiting Keynes in the Light of the Transition to Circular Economy
Authors: Ghisellini Patrizia , Passaro Renato , Ulgiati Sergio 
Published: April 2021

AbstractThe study briefly recalls the evolution and crisis of the theory and thought of John Maynard Keynes with the rise and progressive dominance of the neoliberalism paradigm. The exercise has been made for evaluating the effects of such process for the sustainability of the global economy and society. In this view, we explored how Keynes’ contribution could be useful for the global economy in building a new paradigm of socio-economic development underpinning the transition to circular economy (CE). We also evaluated the adoption of the Global Green New Deal including a case study of Italy for the purpose of suggesting how that topical political programme can be key in the CE transition. Given the urgency of environmental problems, we underline the importance of the adoption of Keynesian expansionary “green mission oriented” fiscal policies with the purpose of allowing the triggering of a virtuous circle of sustainable welfare involving the Green New deal and the transition to CE. At the basis of such virtuous circle, we propose a new paradigm based on a revisited Keynesian paradigm and models of economy within the framework of Genovesi’s “civil economy” that entails an active role and responsibility of all the societal actors (consumers, companies and institutions). In this view, the “spirit” of Keynes in the economy, policy and society could be appreciated once more and be extremely useful along with other scholars’ contributions in accelerating the CE transition and a more sustainable development.
Precision of fiducial marker alignment for correlative super‐resolution fluorescence and transmission electron microscopy
Authors: Fathima Adeeba , Quintana-Cataño César Augusto , Heintze Christoph , Schlierf Michael 
Published: April 2021

AbstractRecent advances in microscopy techniques enabled nanoscale discoveries in biology. In particular, electron microscopy reveals important cellular structures with nanometer resolution, yet it is hard, and sometimes impossible to resolve specific protein localizations. Super-resolution fluorescence microscopy techniques developed over the recent years allow for protein-specific localization with ~ 20 nm precision are overcoming this limitation, yet it remains challenging to place those in cells without a reference frame. Correlative light and electron microscopy (CLEM) approaches have been developed to place the fluorescence image in the context of a cellular structure. However, combining imaging methods such as super resolution microscopy and transmission electron microscopy necessitates a correlation using fiducial markers to locate the fluorescence on the structures visible in electron microscopy, with a measurable precision. Here, we investigated different fiducial markers for super-resolution CLEM (sCLEM) by evaluating their shape, intensity, stability and compatibility with photoactivatable fluorescent proteins as well as the electron density. We further carefully determined limitations of correlation accuracy. We found that spectrally-shifted FluoSpheres are well suited as fiducial markers for correlating single-molecule localization microscopy with transmission electron microscopy.