bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical analysis of frictional charging and electrostatic interaction of particles
Authors: Hu Jiawei , Pei Chunlei , Zhang Ling , Liang Cai , Wu Chuan‐Yu 
Published: September 2021

AbstractTriboelectrification due to frictional contacts between particles and surfaces is prevalent in many powder handling processes. Aiming to explore the friction‐induced electrostatic charging behavior, a discrete element method (DEM) is developed for the first time in the current article, in which a frictional charging model and electrostatic interaction models are implemented. The charge accumulation on both the particles and the surface in a rotational container is then analyzed numerically and experimentally to evaluate the developed DEM. The numerical results for the frictional electrification between insulant particles and an insulant wall agree well with the experimental measurement. It is also shown that both the net charge on the particles and the degree of the particle dispersion are a function of the charging time. Moreover, it is revealed that the friction‐induced particle charge enhances particle dispersion, and increases the granular temperature due to the electrostatic interactions.
Three‐dimensional‐printed millireactor with yeast immobilized in calcium‐alginate film for application in fermentation processes
Authors: Lopes Mariana G. M. , Santana Harrson S. , da Silva Adriano G. P. , Taranto Osvaldir P. 
Published: September 2021

AbstractAn innovative method of alcoholic fermentation was proposed by developing a microfluidic device with millichannels filled with yeast immobilized in alginate hydrogel, manufactured by a new robotic system. We propose and build an automatic equipment consisting of a modified three‐dimensional (3D) printer with two independent systems, a module with a syringe for the injection of solutions/hydrogels and a conventional head with a fused filament fabrication mechanism. The methodology consisted of hydrogel 3D printing tests, the manufacture of millireactors with immobilized yeast and the application of the millireactors in alcoholic fermentation. The 22G needle provided the best printing accuracy in tests with hydrogel. The cells were homogeneously distributed by alginate and their concentration did not influence ethanol production. The optimal millireactor configuration was 2% alginate solution containing 25 g L−1 cells, achieved average ethanol production of 11.24 ± 0.015 g L−1, with productivity of 22.49 g L−1 h−1 and efficiency of 44%.
Responsiveness of fecal immunoglobulin A to HPA‐axis activation limits its use for mucosal immunity assessment
Authors: Behringer Verena , Müller‐Klein Nadine , Strube Christina , Schülke Oliver , Heistermann Michael , Ostner Julia 
Published: September 2021

AbstractThe assessment of mucosal immunity as a component of animal health is an important aspect for the understanding of variation in host immunity, and its tradeoff against other life‐history traits. We investigated immunoglobulin A (IgA), the major type of antibody associated with mucosal immunity, in relation to changes in parasitic burden following anthelminthic treatment in noninvasively collected fecal samples in a semi‐free ranging group of Barbary macaques (Macaca sylvanus). We measured IgA in 340 fecal samples of fourteen females and nine males. As IgA has been found to be responsive to stressors, we also related fecal IgA (fIgA) levels to fecal glucocorticoid metabolites (fGCM) measured in the same samples as part of a previous study. We found a high variability within and between individual fIgA levels over time. Running generalized additive mixed models, we found that fIgA levels were higher in males than in females, but did not change in response to the anthelmintic treatment and the resulting reduction in worm burden. Instead, fIgA level changes were significantly correlated to changes in fGCM levels. Our findings indicate that due to the strong responsiveness of fIgA to HPA‐axis activity, the measurement of fIgA may have certain limitations with respect to reflecting gastrointestinal parasitic burden. Moreover, the responsiveness of fIgA to stressors interferes with the interpretation of IgA levels in fecal samples as a measure of mucosal immunity, at least in our study population of the Barbary macaques.
Is Indigeneity hidden in the shadow of Australian national school reforms?
Authors: Brown Prudence R. , Warner Sarah A. 
Published: September 2021

AbstractWithin a policy regime increasingly focused on measurement, Australian Indigenous students are highly visible in school education debates as underperforming subjects for intervention. This is consistent with broader Indigenous policy discourse, which highlights disadvantage and deficit. At the same time, their Indigeneity, while acknowledged in principle, becomes less visible as the concentration on English literacy and the increasing focus on schooling as a pathway to economic participation has intensified. Recent shifts in education policy narratives of Indigeneity have the potential to counter these trends, and allow Indigeneity to emerge from the shadows of dominant policy frameworks. In this article, we argue that these shifts, while too early to translate into outcomes, deserve attention.
Rational Design, Synthesis and Evaluation of Oxazolo[4,5‐c]‐quinolinone Analogs as Novel Interleukin‐33 Inhibitors
Authors: Kim Yujin , Ma Chao , Park Seonghu , Shin ‐ Yujin , Lee Taeyun , Paek Jiwon , Hoon Kim Kyong , Jang Geonhee , Cho Haelim , Son Seyoung , Son Sang‐Hyun , Yong Lee Ki , Lee Kiho , Woo Jung Yong , Ho Jeon Young , Byun Youngjoo 
Published: September 2021

AbstractInterleukin‐33 (IL‐33) is an epithelial‐derived cytokine that plays an important role in immune‐mediated diseases such as asthma, atopic dermatitis, and rheumatoid arthritis. Although IL‐33 is considered a potential target for the treatment of allergy‐related diseases, no small molecule that inhibits IL‐33 has been reported. Based on the structure‐activity relationship and in vitro 2D NMR studies employing 15N‐labeled IL‐33, we identified that the oxazolo[4,5‐c]‐quinolinone analog 7 c binds to the interface region of IL‐33 and IL‐33 receptor (ST2), an orphan receptor of the IL‐1 receptor family. Compound 7 c effectively inhibited the production of IL‐6 in human mast cells in a dose‐dependent manner. Compound 7 c is the first low molecular weight IL‐33 inhibitor and may be used as a prototype molecule for structural optimization and investigation of the IL‐33/ST2 signaling pathway.
Real option valuation of timber harvesting contracts
Authors: Herath Hemantha S. B. , Jahera John S. 
Published: September 2021

AbstractA primary challenge for forestry businesses is valuing timber harvesting contracts. This article presents an empirical application of determining the optimal harvest volumes under stochastic prices to determine the economic value of timber harvesting contracts and manage business risk using real options theory. We illustrate a dynamic optimization solution procedure and the choice between a single long‐term versus two short‐term timber harvesting contracts from a risk management perspective. A case study of timber harvesting contracts sold in British Columbia is used to demonstrate specification of the many details and adaptations that are required in such valuation problems. Our article offers some interesting results. The highest timber harvesting contract values occur with optimal harvest quantities rather than an equal annual allowable cut (AAC). The difference in values can be substantial (two to three‐fold). Consequently, forestry businesses can benefit by timing their harvest to nonequal quantities in later years of a timber harvesting contract. Depending on the quality of timber, the maximum stumpage value for the second short‐term timber harvesting contract ranges from $12 to $17.8 per cubic meter, resulting in lower profit margins for equal AAC. In contrast, with optimal harvesting, the maximum stumpage value ranges from $2 to $8.5 per cubic meter and higher profit margins. These bounds for stumpage price and profit margins would be useful for forest businesses to better manage business risks when bidding for timber harvesting contracts.
Stem cell‐based and mesenchymal stem cell derivatives for coronavirus treatment
Authors: Rafiee Zeinab , Nejaddehbashi Fereshteh , Nasrolahi Ava , Khademi moghadam Fatemeh 
Published: September 2021

AbstractCoronavirus disease 2019 (COVID‐19) as one of the types of pneumonia was first reported in Wuhan, China in December 2019. COVID‐19 is considered the third most common coronavirus among individuals after acute respiratory syndrome (SARS‐CoV) and the Middle East respiratory syndrome (MERS‐CoV) in the 20th century. Many studies have shown that cell therapy and regenerative medicine approaches have an impressive effect on different dangerous diseases in a way that using a cell‐based experiment could be effective for improving humans with severe acute respiratory infections caused by the 2019 novel coronavirus. Accordingly, due to the stunning effects of mesenchymal stem cells (MSCs) and derivatives on the treatment of various diseases, this review focuses on the auxiliary role of MSCs and their derivatives in reducing the inflammatory processes of acute respiratory infections resulted from the 2019 novel coronavirus. The reported MSCs treatment outcomes are significant because these cells prevent the immune system from overactivating and improve, endogenous repair by improving the lung microenvironment after the SARS‐CoV‐2 infection. The MSCs can be an effective, autologous, and safe treatment, and therefore, share the results. To date, the results of several studies have shown that MSCs and their derivatives can inhibit inflammation. Exosomes act as intercellular communication devices between cells for the transfer of active molecules. In this review, recent MSCs and their derivatives‐based clinical trials for the cure of COVID‐19 are introduced.
Designing DNA probe from HPV 18 and 58 in the E6 region for sensing element in the development of genosensor‐based gold nanoparticles
Authors: Jaapar F. Nadhirah , Parmin N.A. , Halim N. Hamidah A , Hashim Uda , Gopinath Subash C.B. , Halim F. Syakirah , Ruslinda A. Rahim , Voon C.H. , Uda M.N.A. , Uda M.N.Afnan , Nadzirah Sh. , Rejali Zulida , Afzan Amilia , Zakaria Iffah Izzati 
Published: September 2021

AbstractThe E6 region has higher protuberant probability annealing than consensus probe focusing on another region in the human papillomavirus (HPV) genome in terms of detection and screening method. Here, we designed the first multiple virus single‐stranded deoxyribonucleic acid (ssDNA) for multiple detections in an early phase of screening for cervical cancer in the E6 region and became a fundamental evolution of detection electrochemical HPV biosensor. Gene profiling of the virus ssDNA sequences has been carried by high‐end bioinformatics tools such as GenBank, Basic Local Alignment Searching Tools (BLAST), and Clustal OMEGA in a row. The output from bioinformatics tools resulted in 100% of similarities between our virus ssDNA probe and HPV complete genome in the databases. The cross‐validation between HPV genome and our designed virus ssDNA provided high specificity and selectivity during screening methods compared with Pap smear. The DNA probe for HPV 18, 5′ COOH‐GAT CCA GAA GGT ACA GAC GGG GAG GGC ACG 3′, while 5′COOH‐GGG CGC TGT GCA GTG TGT TGG AGA CCC CGA3′ as DNA probe for HPV 58 designed with 66.77% guanine (G) and cytosine (C) content for both. Our virus ssDNA probe for the HPV biosensor promises high sensitivity, specificity, selectivity, repeatability, low fluid consumption, and will be useful in mini‐size diagnostic devices for cervical cancer detection.
Effects of the COVID‐19 pandemic in a preexisting longitudinal study of patients with recently diagnosed bipolar disorder: Indications for increases in manic symptoms
Authors: Koenders Manja , Mesbah Rahele , Spijker Annet , Boere Elvira , de Leeuw Max , van Hemert Bert , Giltay Erik 
Published: September 2021

AbstractBackgroundThe coronavirus disease 2019 (COVID‐19) pandemic interfered in the daily lives of people and is assumed to adversely affect mental health. However, the effects on mood (in)stability of bipolar disorder (BD) patients and the comparison to pre‐COVID‐19 symptom severity levels are unknown.MethodBetween April and September, 2020, symptoms and well‐being were assessed in the Bipolar Netherlands Cohort (BINCO) study of recently diagnosed patients with BD I and II. The questionnaire contained questions regarding manic and depressive symptoms (YMRS and ASRM, QIDS), worry (PSWQ), stress (PSS), loneliness, sleep, fear for COVID‐19, positive coping, and substance use. As manic, depressive and stress symptoms levels were assessed pre‐COVID‐19, their trajectories during the lockdown restrictions were estimated using mixed models.ResultsOf the 70 invited BD patients, 36 (51%) responded at least once (mean age of 36.7 years, 54% female, and 31% BD type 1) to the COVID‐19 assessments. There was a significant increase (X2 = 17.06; p = .004) in (hypo)manic symptoms from baseline during the first COVID‐19 wave, with a decrease thereafter. Fear of COVID‐19 (X2 = 18.01; p = .003) and positive coping (X2 = 12.44; p = .03) were the highest at the start of the pandemic and decreased thereafter. Other scales including depression and stress symptoms did not vary significantly over time.ConclusionWe found a meaningful increase in manic symptomatology from pre‐COVID‐19 into the initial phases of the pandemic in BD patients. These symptoms decreased along with fear of COVID‐19 and positive coping during the following months when lockdown measures were eased.
A Systematic Review on Phytochemistry, Ethnobotany and Biological Activities of the Genus Bunium L.
Authors: Mohammadhosseini Majid , Frezza Claudio , Venditti Alessandro , Sarker Satyajit D. 
Published: September 2021

AbstractThe aim of this review article is to present, for the first time, an appraisal of the phytochemical, ethnobotanical and pharmacological data on Bunium species. The literature search was conducted using the Scopus, Google Scholar and PubMed databases. The genus Bunium has been found to produce both essential oil (EO), mainly comprising monoterpenes and sesquiterpenes, and non‐volatile components mainly coumarins and flavonoids. There are several pharmacological activities associated with the Bunium species, especially antioxidant, antibacterial and antifungal properties. The chemotaxonomic appraisal of the phytochemical pattern of the genus is in sink with the current classification of the family. Moreover, this review confirms the significant ethnobotanical and pharmacological potential of different Bunium species.
Cation Decorated Ferric Oxide with a Polyhedral‐like Structure for the Electrocatalytic Nitrogen Reduction Reaction
Authors: Zhao Mingzhu , Guo Chengying , Gao Lingfeng , Yang Hua , Liu Chengqing , Kuang Xuan , Sun Xu , Wei Qin 
Published: September 2021

AbstractConsiderable efforts have been devoted to electrocatalytic reaction of N2 to NH3 driven by the broad demand of ammonia and the disadvantages of the Haber‐Bosch process. Unfortunately, the difficult adsorption of nitrogen molecules and the permanent dipole of N≡N vastly inhibit its practical application. Historically, the ferric oxide (Fe2O3) has inferior nitrogen reduction reaction (NRR) activity among transition compounds due to the unfavorable band gap and scarce active center. Considering the fact that the electronic properties and morphology character could be well‐tuned brought by the incorporation of heteroatoms, we report vanadium atom decorated ferric oxide (named as V‐α‐Fe2O3) with a polyhedral‐like structure as an innovative catalyst for fast nitrogen reduction reaction. Benefiting from the incorporation of vanadium atoms, the electronic structure and active center of α‐Fe2O3 were well‐optimized, with enhanced NRR activity being obtained. The as‐synthesized 17 % V‐α‐Fe2O3 exhibits excellent catalytic activity that the Faradaic efficiency is 5.7 % and the NH3 yield is 68.7 μg h−1 mg−1cat. at −0.2 V (vs. RHE) in 0.1 M HCl. This work reported an approach to synthesize the enhanced catalysts even realizing the efficient application of NRR in the near future.
Constructing Highly Efficient Blue OLEDs with External Quantum Efficiencies up to 7.5 % Based on Anthracene Derivatives
Authors: Zheng Xu‐Hui , Huang Ting‐Ting , Yang Guo‐Xi , Lin An‐Qi , Chen Keng , Chen Xiang , Li Jiu‐Yan , Tong Qing‐Xiao 
Published: September 2021

AbstractAcquiring desirable device performance with deep‐blue color purity that fulfills practical application requirements is still a challenge. Bipolar fluorescent emitters with hybrid local and charge transfer (HLCT) state may serve to address this issue. Herein, by inserting anthracene core in the deep‐blue building blocks, the authors successfully developed two highly twisted D‐π‐A fluorescent emitters, ICz‐An‐PPI and IP‐An‐PPI, featuring different acceptor groups. Both exhibited superb thermal stabilities, high photo luminescent quantum yields and excellent bipolar transport capabilities. The non‐doped OLEDs using ICz‐An‐PPI and IP‐An‐PPI as the emitting layers showed efficient blue emission with an external quantum efficiency (EQEmax) of 4.32 % and 5.41 %, and the CIE coordinates of (0.147, 0.180) and (0.149, 0.150), respectively. In addition, the deep blue doped device based on ICz‐An‐PPI was achieved with an excellent CEmax of 5.83 cd A−1, EQEmax of 4.6 % and the CIE coordinate of (0.148, 0.078), which is extremely close to the National Television Standards Committee (NTSC) standard. Particularly, IP‐An‐PPI‐based doped device had better performance, with an EQEmax of 7.51 % and the CIE coordinate of (0.150, 0.118), which was very impressive among the recently reported deep‐blue OLEDs with the CIEy <0.12. Such high performance may be attributed to the hot exciton HLCT mechanism via T7 to S2. Our work may provide a new approach for designing high‐efficiency deep‐blue materials.
Active Living After Cancer: Adaptation and evaluation of a community‐based physical activity program for minority and medically underserved breast cancer survivors
Authors: Tami‐Maury Irene M. , Liao Yue , Rangel Maria L. , Gatus Leticia A. , Shinn Eileen H. , Alexander Ashley , Basen‐Engquist Karen 
Published: September 2021

BackgroundAn expanding body of research documents the benefits of physical activity for cancer survivors' physical functioning and quality of life, but few successful models provide community‐based physical activity programs to cancer survivors. This report presents an evaluation of Active Living After Cancer, an evidence‐based physical activity program for breast cancer survivors, adapted for community delivery to minority and medically underserved survivors.MethodsSurvivors were recruited from health care and community settings. The program consisted of 12 weekly group sessions providing training in cognitive and behavioral skills for behavior change, brief physical activity, and cancer survivorship‐related content. At the baseline and follow‐up, participants completed assessments of their physical activity, quality of life, and physical functioning (6‐minute walk and 30‐second sit‐to‐stand test). At follow‐up, they also completed questionnaires to measure program content mastery and satisfaction.ResultsThe outcome analysis included 127 participants. Physical activity and quality of life (mental and physical) improved from the baseline to follow‐up (all P < .01). Physical functioning improved, with increases in sit‐to‐stand repetitions (mean, 12.5 at the baseline vs 14.9 at the follow‐up; P < .01) and 6‐minute walk distances (mean, 428 m at the baseline vs 470 m at the follow‐up; P < .01).ConclusionsThe results highlight the effectiveness of an evidence‐based program adapted for community‐based delivery to minority and medically underserved breast cancer survivors. The program could be delivered to improve outcomes in diverse survivor populations.Lay Summary

Physical activity in breast cancer survivors is related to better quality of life and longer cancer‐free survival. However, there are few community‐based programs to help breast cancer survivors to become more physically active.

The Active Living After Cancer program was adapted from an evidence‐based program and delivered in community‐based settings to minority and medically underserved breast cancer survivors. It consisted of 12 weekly group sessions in which participants learned skills to increase their physical activity.

The program participants increased their physical activity and improved their mental and physical well‐being and physical functioning.
Retracted: A multi‐modality paradigm for CT and MRI fusion with applications of quantum image processing
Authors: Dogra Ayush , Ahuja Chirag Kamal , Kumar Sanjeev 
Published: September 2021

AbstractAs pixel resolution continues to increase in images acquired from different sensors, the measurement of the correlation between pixels and their properties requires numerous processing steps over multiple iterations. Quantum image processing (QIP) is a technology capable of processing exponentially large volumes of data within polynomial time. One such application is image fusion. In the field of radiography, computerized tomography (CT) images provide the structural information of bone tissues, and magnetic resonance MR images can provide the visualization of gray‐scale anatomical structures of soft tissues. With the help of CT and MR fusion, a composite image can be obtained containing information on both hard and soft tissues. Clinicians often have to switch between these modalities to trace various patterns for effective staging and diagnosis of various oncological diseases. In this study, a multilevel filtering‐based image fusion algorithm that efficiently fuses information from CT and MR images into a single image has been proposed. First, source images are processed with a rolling guidance filter, and the detail layer is calculated. The base layer is then computed using guided filtering to ensure a high level of edge preservation. Furthermore, to minimize noise and artifacts, the detail layers are fused using the Karhunen–Loeve transform, and the base layers are combined using the weighted superimposition principle. Experimental results demonstrate that the proposed methodology is subjectively more efficient than the existing state‐of‐the‐art methods.
A recommendation approach based on correlation and co‐occurrence within social learning network
Authors: Souabi Sonia , Retbi Asmaâ , Idrissi Mohammed Khalidi , Bennani Samir 
Published: September 2021

SummaryThe context of our work falls within the context of social learning networks, particularly recommendation systems. A recommendation system generally consists of proposing objects and items that meet users' needs and expectations. Within social learning, recommendation systems are of paramount importance as they guide learners in their learning path and facilitate their interactions with learning platforms. However, most recommendation systems in online learning are limited to the use of explicit feedback received from learners. In addition to explicit feedback, the new generation of recommendation systems ought to promote implicit feedbacks and actions taken by the stakeholders. In this article, we propose a hybrid recommendation system integrating all the activities carried out by the learners and combining the two notions of correlation and co‐occurrence. After expounding our system, the evaluation is performed on a database outlining the interaction of employees with articles available within a Deskdrop platform. The results indicate that the performance of the hybrid approach (70%) exceeds the performance of the non‐hybrid recommendation system (30%), and that the hybrid system is more consistent in terms of performance as well.