bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social network analysis of mythology field
Authors: Akça Sümeyye , Akbulut Müge 
Published: May 2021

PurposeThe main purpose of the study is to detect, monitor the mythology field and make predictions of the development of it using social network analysis metrics. Mythology, which is the subject of many disciplines, is an area with extensive working potential. In addition to basic bibliometric indicators, the relationships of this field, which cannot be seen by other methods, were analyzed using measures such as centrality, between, eigenvector, modularity and silhouette coefficients.Design/methodology/approachIn this study, social network analysis of the field of mythology, which has an interdisciplinary structure, was made. Within the scope of the study, 28,370 publications were selected from the publications in the field of mythology in the Web of Science (WoS) citation database between 1900 and 2019 using the probability-based stratified sampling method (5%), and detailed analyzes were made on these publications. The aforementioned publications were analyzed in terms of publication and citation numbers, publication types, subject categories, keywords used, co-authorship, researchers with the highest number of publications, institutions and countries with the highest number of document co-citations.FindingsThe findings show that the field of mythology gathers around four main subjects (sociology, folklore, politics and anthropology). When interpreted in terms of centrality metrics in more detail, the symbiotic or complementary relationship between anthropology, folklore, politics, sociology and mythology can be easily observed.Originality/valueThe findings of this study are seen important for scientists, decision-makers and policymakers. In addition, the findings of the study can be used to create the curriculum of the field.
Internal audit functions, financial reporting quality and moderating effect of senior management support
Authors: Madawaki Abdulkadir , Ahmi Aidi , Ahmad Halimah @ Nasibah 
Published: May 2021

PurposeThe purpose of this paper is to demonstrate the relationship between internal audit functions (IAF) and financial reporting quality (FRQ) and whether such a relationship is moderated by senior management support (SMS) in listed companies in Nigerian Stock Exchange (NSE).Design/methodology/approachThis research is a cross-sectional study, using primary data in the form of a survey sent to 175 listed companies in NSE. A total of 149 questionnaires have been collected and analysed out of which 97 were found to be useful and used in the final analysis.FindingsThe findings indicate a positive and significant relationship between internal audit qualities of work performed, internal control activities, coordination between internal and external auditors and FRQ and this finding was also supported by SMS as a moderator. However, the results show a negative and insignificant relationship between internal audit competency, organisational status and FRQ.Research limitations/implicationsThe findings support the assumption with regard to agency theory. The board should support the IAF to serve as an effective monitoring mechanism in minimising opportunistic management actions. Regulators should also ensure adequate structures that will strengthen the organisational status of the internal auditors to perform towards improving FRQ.Originality/valueThe study contributes to the existing literature by assessing the effect of IAF on FRQ as moderated by SMS.
Message sharing and verification behaviour on social media during the COVID-19 pandemic: a study in the context of India and the USA
Authors: Sharma Anumegha , Kapoor Payal S. 
Published: May 2021

PurposeTechnology has eased access to information. During the ongoing COVID-19 pandemic, ease of access and transmission of information via social media has led to ambiguity, misinformation and uncertainty. This research studies the aforementioned behaviours of information sharing and verification related to COVID-19, in the context of social media.Design/methodology/approachTwo studies have been carried out. Study 1, with Indian social media users, is a two-factor between-subjects experimental design that investigated the effect of message polarity (positive versus negative) and message type (news versus rumour) on the dissemination and verification behaviour of COVID-19-related messages. The study also investigated the mediation of perceived message importance and health anxiety. Study 2 is a replica study conducted with US users.FindingsThe study finding revealed significantly higher message sharing for news than rumour. Further, for the Indian users, message with positive polarity led to higher message sharing and message with negative polarity led to higher verification behaviour. On the contrary, for the US users, message with negative polarity led to higher message sharing and message with positive polarity led to higher verification behaviour. Finally, the study revealed message importance mediates the relationship of message type and message sharing behaviour for Indian and US users; however, health anxiety mediation was significant only for Indian users.Practical implicationsThe findings offer important implications related to information regulation during a health crisis. Unverified information sharing is harmful during a pandemic. The study sheds light on this behaviour such that stakeholders get insights and better manage the information being disseminated.Originality/valueThe study investigates the behaviour of sharing and verification of social media messages between users containing health information (news and rumour) related to the ongoing COVID-19 pandemic.Peer reviewThe peer review history for this article is available at: https://publons.com/publon/10.1108/OIR-07-2020-0282
Systematic review and practical guidance on the use of topical calcipotriol and topical calcipotriol with betamethasone dipropionate as long‐term therapy for mild‐to‐moderate plaque psoriasis
Authors: Zhao Yi , Asahina Akihiko , Asawanonda Pravit , Frez Ma. Lorna , Imafuku Shinichi , Hyun Kim Dong , Theng Colin , Wang Liangchun , Zhang Jiang An , Zimmo Sameer 
Published: May 2021

AbstractWhile many patients with psoriasis are candidates for topical agents, long‐term treatment effects are unclear. This systematic review evaluated global findings from clinical trials and real‐world studies of topical calcipotriol and the two‐compound formulation of calcipotriol and betamethasone dipropionate for mild‐to‐moderate plaque psoriasis (including scalp psoriasis). PubMed, Embase and MEDLINE were searched for relevant English‐language publications along with Chinese, Japanese, Korean and Latin American publication databases. Identified articles were screened by title and abstract against predefined inclusion/exclusion criteria. A narrative synthesis of key efficacy and safety findings from the full papers of selected publications was developed. Thirty‐seven relevant papers were identified (25 English, 11 Chinese and one Japanese‐language study) including 28 randomized controlled trials. While there was significant heterogeneity in study length, treatment intensity and clinical measures, following a critical review of the published data combined with expert opinion, the following clinical practice recommendations were agreed in order to assist healthcare providers: in adults, long‐term treatment with calcipotriol/betamethasone dipropionate is well tolerated and efficacious for up to 1 year on an ‘as needed’ basis, and for up to 16 weeks on a fixed‐treatment regimen. Calcipotriol is also well tolerated and efficacious when used long term (up to 52 weeks) ‘as needed’ and for up to 20 weeks on a fixed‐treatment regimen. Used on an ‘as needed’ basis for up to 1 year, the safety and efficacy profile of fixed‐dose combination calcipotriol/betamethasone dipropionate is more favorable than calcipotriol alone; regular consultation between patients and their dermatologist/primary care physician is required to review psoriasis symptoms and adjust treatment accordingly; a specific treatment goal should be agreed on initiation of topical agent(s) to determine when long‐term treatment can begin or if a regimen change is warranted; and application frequency during the continued treatment phase should consider the patients’ treatment expectations and goals.
Angiotensin involvement in kidney injury induced by rheumatoid arthritis in rat
Authors: Carlos Carla Patrícia , de Carvalho Enzo Prandi , Angeli Junior Euradir Vitório , Garcia Filho Glayber Falcão , Doná João Pedro Lot , Batanero Rodrigo Piloto de Oliveira , Guena Rafael de Oliveira , Agren Camila , Baptista Maria Alice Sperto Ferreira , Bizotto Thaís Santana Gastardelo , Cury Patricia Maluf , Chies Agnaldo Bruno 
Published: May 2021

AbstractRenal injury induced by rheumatoid arthritis is not clear and may be related to the angiotensin II. We aim to investigate the adjuvant‐induced arthritis (AIA) injury in rat kidney, focusing the angiotensin II/AT1 pathway. Male Wistar rats were allocated in to three groups: Control, AIA and AIA plus losartan. The AIA was induced by injection of 100 µL of an emulsion of dissected Mycobacterium tuberculosis (50 mg/mL) on the paw. Treatment with losartan was initiated on the first day of immunization (daily subcutaneous injection, 1 mg/kg). After 60 days post immunization, we evaluated kidney function by plasma creatinine, urea and uric acid levels and creatinine depuration; kidney injury by apoptosis analysis and inflammation markers such as macrophages, transforming growth factor beta (TGF‐β) and inducible nitric oxide synthase (iNOS) expression; oxidative stress by plasma thiobarbituric acid reactive substances (TBARS); renal expression of angiotensin receptors subtype 1 (AT1) and 2 (AT2) and plasma concentration of angiotensin II. AIA rats showed elevated plasma levels of creatinine, urea, uric acid, TBARS and Ang II and reduced creatinine depuration, and enhanced kidney macrophage number, TGF‐β, caspase‐3, iNOS and AT1/AT2 receptors expression. The losartan reduced plasma creatinine and its clearance, reduced macrophages and the expression of TGF‐β and iNOS in renal tissues, and reduced plasma TBARS. We conclude that AIA causes kidney injury by a physiopathological mechanism that involves AT1 stimulation in renal tissue, elevating the presence of macrophages, the expression of TGF‐β and iNOS, as well the local oxidative stress, which contribute to renal function deterioration.
Polysaccharide degradation by the Bacteroidetes: mechanisms and nomenclature
Authors: McKee Lauren S. , La Rosa Sabina Leanti , Westereng Bjørge , Eijsink Vincent G. , Pope Phillip B. , Larsbrink Johan 
Published: May 2021

SummaryThe Bacteroidetes phylum is renowned for its ability to degrade a wide range of complex carbohydrates, a trait that has enabled its dominance in many diverse environments. The best studied species inhabit the human gut microbiome and use polysaccharide utilization loci (PULs), discrete genetic structures that encode proteins involved in the sensing, binding, deconstruction, and import of target glycans. In many environmental species, polysaccharide degradation is tightly coupled to the phylum‐exclusive type IX secretion system (T9SS), which is used for the secretion of certain enzymes and is linked to gliding motility. In addition, within specific species these two adaptive systems (PULs and T9SS) are intertwined, with PUL‐encoded enzymes being secreted by the T9SS. Here, we discuss the most noteworthy PUL and non‐PUL mechanisms that confer specific and rapid polysaccharide degradation capabilities to the Bacteroidetes in a range of environments. We also acknowledge that the literature showcasing examples of PULs is rapidly expanding and developing a set of assumptions that can be hard to track back to original findings. Therefore, we present a simple universal description of conserved PUL functions and how they are determined, while proposing a common nomenclature describing PULs and their components, to simplify discussion and understanding of PUL systems.
Camelot Caves Incorporated: An Instructional Case*
Authors: Lapointe‐Antunes Pascale , Sainty Barbara , Skrubbeltrang Glenn 
Published: May 2021

ABSTRACTThe case asks you to prepare a report and presentation to the shareholders of Camelot Caves Incorporated (CCI), a privately held winery located in Niagara‐on‐the‐Lake, Ontario, Canada. CCI has approached your firm to assist them in setting a new direction for the company. The shareholders need to make critical decisions about the company's operations, but they cannot seem to agree. You must obtain an understanding of CCI's current vision and mission, strategic position, and financial situation before analyzing the strategic fit and quantitative and qualitative implications of the alternatives under consideration—including the addition of a new distribution channel, the opening of a restaurant, and the production of ice wine—and considering the impact of your recommendations on the value of the business and its cash position. The case will allow you to integrate a number of issues faced by a small business seeking growth through evaluating strategic and operational issues and providing recommendations.
National birth prevalence, associated anomalies and mortality for gastroschisis in Sweden
Authors: Caldeman Cecilia , Fogelström Anna , Oddsberg Jenny , Mesas Burgos Carmen , Löf Granström Anna 
Published: May 2021

AbstractAimAn increased incidence has been reported for the congenital abdominal wall defect gastroschisis. The reason for this increasing trend is not known, nor the aetiology. The aim of this study was to examine the national birth prevalence in Sweden, the termination rate, associated anomalies and the mortality of gastroschisis within the cohort.MethodsA nationwide, population‐based descriptive study of children born with gastroschisis in Sweden between 1/1 1997 and 31/12 2016 was conducted. The cohort was collected from the Swedish Medical Birth Register and the Swedish National Patient Register. Several other national registers were then interlinked to identify outcome data.ResultsThe study included 361 cases of gastroschisis, 54% female. The birth prevalence was 1.52 in 10,000 live births. The termination rate was 21%. The mortality within the cohort was 4.4% with a 1‐year mortality of 3.9%. Most frequent associated anomalies were gastrointestinal (11.4%), musculoskeletal (9.8%) and cardiovascular anomalies (7.9%).ConclusionDuring the 20‐year study period, a stable birth prevalence of 1.52 per 10 000 live births was seen in Sweden. The mortality was low, 4.4%, but the termination of pregnancies was high, 21%. Almost one‐third had associated congenital anomalies where gastrointestinal anomalies were the most common.
Mitochondria transfer from early stages of erythroblasts to their macrophage niche via tunnelling nanotubes
Authors: Yang Chong , Endoh Mitsuhiro , Tan Darren Q. , Nakamura‐Ishizu Ayako , Takihara Yuji , Matsumura Takayoshi , Suda Toshio 
Published: May 2021

SummaryAdult erythropoiesis entails a series of well‐coordinated events that produce mature red blood cells. One of such events is the mitochondria clearance that occurs cell‐autonomously via autophagy‐dependent mechanisms. Interestingly, recent studies have shown mitochondria transfer activities between various cell types. In the context of erythropoiesis, macrophages are known to interact closely with the early stages of erythroblasts to provide a specialized niche, termed erythroblastic islands (EBI). However, whether mitochondria transfer can occur in the EBI niche has not been explored. Here, we report that mitochondria transfer in the EBI niche occurs in vivo. We observed mitochondria transfer activities from the early stages of erythroblasts to macrophages in the reconstituted in vitro murine EBI via different modes, including tunnelling nanotubes (TNT). Moreover, we demonstrated that Wiskott‐Aldrich syndrome protein (WASp) in macrophages mediates TNT formation and mitochondria transfer via the modulation of F‐actin filamentation, thus promoting mitochondria clearance from erythroid cells, to potentially enhance their differentiation. Taken together, our findings provide novel insight into the mitochondria clearance machineries that mediate erythroid maturation.
Soft tissue integration of different abutment surfaces: An experimental study with histological analysis
Authors: Canullo Luigi , Penarrocha Oltra David , Pesce Paolo , Zarauz Cristina , Lattanzio Rossano , Penarrocha Diago Miguel , Iezzi Giovanna 
Published: May 2021

AbstractObjectiveTo evaluate whether abutment surface and surface bio‐activation have an effect on soft tissue morphogenesis.Materials and Methods36 patients (36 implants) were included. Abutments were randomly divided into 4 groups (n = 9): Smooth Surface—MAChined (MAC), Ultrathin Threaded Microsurface (UTM), MAC Plasma of Argon activated (Plasma‐MAC), and UTM Plasma of Argon activated (Plasma‐UTM). After 2 months of healing, soft tissue samples were collected and prepared for histological analysis. The margin of the peri‐implant mucosa (PM), the apical extension of the barrier epithelium (aJE), and the apical location of the abutment (AM) were identified. Significances of differences among groups were tested by means of the Kruskal–Wallis test and between pairs of results by means of the Mann–Whitney test.ResultsThe mean (SD) vertical dimension of the mucosa was 2.5mm (1.0), including a connective tissue portion (CTP) of 0.8mm (0.8) in the MAC group; 3.6mm (0.2) with a CTP of 1.6mm (0.4) in the Plasma‐MAC group; 3.2mm (1.0), with a CPT of 0.5mm (0.6) in the UTM; and 3.3mm (0.8), with a CPT of 0.9mm (0.7) in the Plasma‐UTM group. Statistically significant differences were observed in the aJE‐AM height and PM‐aJE profile among the four experimental groups (p = .042 and p = .039, respectively). The Mann–Whitney test indicated differences between the Plasma‐abutments and the untreated abutments both for PM‐AM (p = .025) and AjE‐AM (p = .021). The differences appeared more evident when the preoperative soft tissue thickness was ≤2mm.ConclusionsWithin its limits, the study demonstrated a favorable effect of the plasma treatment on the connective tissue portion tissues. Plasma‐MAC group highlighted the best performance. This behavior appeared strictly correlated with the soft tissue thickness.
Using temporal occupancy to predict avian species distributions
Authors: Snell Taylor Sara , Di Cecco Grace , Hurlbert Allen H. 
Published: May 2021

AbstractAimSpecies distribution models (SDMs) are ubiquitous in ecology to predict species occurrence throughout their range. Typically, SDMs are created using presence‐only or presence–absence data. We hypothesize that the continuous metric of temporal occupancy, the proportion of time a species is observed at a given site, provides more detail about species occurrence than binary presence‐based SDMs.LocationNorth America.MethodsWe compared SDMs for 189 focal species using four modelling methods to determine whether North American avian species distributions are better predicted using temporal occupancy over presence–absence. We used the North American Breeding Bird Survey and built SDMs based on all sites sampled consecutively between 2001 and 2015, as well as on a subset of only five time points within the 15‐year sampling window. Each model used the same environmental inputs to predict species range. Each SDM was cross‐validated temporally and spatially.ResultsSpecies distributions were generally better predicted using temporal occupancy rather than presence–absence when using either a five‐year or fifteen‐year sampling window. Species that occurred in a smaller proportion of their predicted range were particularly better predicted with SDMs using temporal occupancy. Temporal occupancy SDMs had lower false discovery and false‐positive rates but higher false‐negative rates than presence–absence models.Main conclusionsTemporal occupancy is a valuable metric that can improve predictions of species occurrence for birds and may improve conservation planning and design efforts.
Organisational accreditation, workforce training and perceptions of performance
Authors: Haile Getinet Astatike 
Published: May 2021

AbstractThe paper examines if the ‘Investors in People’ (IiP) organisational accreditation scheme promoted worker training and organisational performance in Britain using a panel of organisations. DID matching estimators relating to both employee‐ and employer‐assessed training outcomes revealed that IiP status promoted workforce training, but only for private sector organisations. Conversely, losing the status was not found to have a significant training link. On organisational performance, the estimates revealed that gaining (losing) the status had a significant positive (negative) link with managers' perceptions of organisational performance in both sectors. Public sector organisations are reported to have a relative strength in workforce training, which appears to explain the lack of significant training link. The sector may thus require a different scheme to promote workforce training further.
Single‐cell transcriptome analysis of human oocyte ageing
Authors: Yuan Lihua , Yin Ping , Yan Hua , Zhong Xiufang , Ren Chunxia , Li Kai , Chin Heng Boon , Zhang Wuwen , Tong Guoqing 
Published: May 2021

AbstractOocyte ageing is a key bottleneck and intractable challenge for in vitro fertilization treatment of aged female patients. The underlying molecular mechanisms of human oocyte ageing remain to be elucidated. Hence, this study aims to investigate the key genes and relevant biological signalling pathways involved in human oocyte ageing. We isolated mRNA for single‐cell RNA sequencing from MII human oocytes donated by patients undergoing intracytoplasmic sperm injection. Nine RNA‐seq datasets were analyzed, which included 6 older patients(average 42.67±2.25 years) and 3 younger patients (average 25.67±2.08 years). 481 differentially expressed genes (DEGs) were identified, including 322 upregulated genes enriched in transcription, ubiquitination, epigenetic regulation, and cellular processes, and 159 downregulated genes enriched in ubiquitination, cell cycle, signalling pathway, and DNA repair. The STRING database was used to analyse protein‐protein interactions, and the Cytoscape software was used to identify hub genes. From these DEGs, 17 hub genes were identified including 12 upregulated genes (UBE2C, UBC, CDC34, UBR1, KIF11, ASF1B, PRC1, ESPL1, GTSE1, EXO1, UBA1, KIF4A) and 5 downregulated genes (UBA52, UBE2V2, SKP1, CCNB1, MAD2L1). The significant key biological processes that are associated with these hub genes include ubiquitin‐mediated proteolysis, ubiquitination‐related pathways, oocyte meiosis, and cell cycle. Among these, UBE2C may play a crucial role in human oocyte ageing.