bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study On Urban Rainstorm Pattern of Short-Duration Double-Peak
Authors: Zhang Jinping , Kong Lingli , Fang Hongyuan 
Published: May 2021

Abstract
At present, researches on urban short-duration rainstorm patterns mainly focus on single-peak rainstorm patterns, and rarely involve double-peak rainstorm patterns, or convert double-peak patterns into single-peak patterns directly, even ignore the impact of double-peak patterns, which directly affects the urban flood planning and early warning and rescue. To scientifically and rationally deduce the urban short duration double-peak rain pattern, this paper proposes a new function fitting rain pattern method by constructing double-peak virtual rain peak rainfall and virtual rain peak coefficient (RPC), based on the idea of convert double-peak to singel-peak, then revert to the double-peak, directly deducing the double-peak rain pattern.The results show that (1) The rain pattern derived by the function fitting rain pattern method(FFRPM) can effectively improve the accuracy of the double-peak rain pattern, and is also more practical; (2) The fitting degree of function fitting rainfall pattern and actual rain pattern is more than 90%, accounting for 80%, the fitting degree of main and secondary peak rainfall is more than 90%, with an average of about 95%; the accuracy of the main and secondary peak positions is also relatively high; (3) Compared with the P&C rain pattern method(RPM), whether the overall accuracy or local peak rainfall, the FFRPM has the higher accuracy, especially more accurate on rain peak rainfall.
Safety and Efficacy of Tomosynthesis-guided Breast Biopsies in the Prone Position: Mono-centric Study and Review of the Literature.
Authors: Catelli Antonio , Santoro Angela , Antignani Elena , Venetucci Pietro , Minelli Salvatore 
Published: May 2021

Abstract
Purpose: The purpose of this study is to describe the safety and efficacy of 9G needle biopsy under tomosynthesis guidance with the patient in the prone position.Materials and methods: This is a retrospective observational study conducted on patients with non-palpable breast mass exclusively detectable through tomosynthesis, performed from the 1st January 2018 to the 1st August 2020. The procedures were performed by taking 12 tissue samples from each mass. The evaluated technical success was considered as a conclusive sample for histological diagnosis. We performed a comparison between the procedural data of interventions in patients who have a lesion <or = 10mm and> 10mm and between high contrast and low contrast masses. The histological data of the samples were analyzed.Results: 500 biopsies of the total 1500 performed from the 1st January 2018 to the 1st August 2020 were included in the study; repetitions for inadequate withdrawal occurred 0.4% (3/500). No major complications have ever been observed. Two cases (0.2%) of minor bleeding were observed with self-limited bleeding from the skin breach at 90 minutes without clinical sequelae in an asymptomatic patient. The biopsy samples showed carcinoma in 55.2% (276/500). Conclusion: Our study suggests that the 9G needle sampling biopsy procedure through tomosynthesis guide with prone patient is a safe and effective procedure for the characterization of indeterminate breast mass.
Exploration of Ion Sensitive Field-Effect Transistor With Dielectric Properties
Authors: Kumar Abhishek , Tripathi Suman Lata 
Published: May 2021

Abstract
Environmental changes and increased virus effects in COVID-19 like the situation is forcing the design and researchers to develop highly sensitive, low power and low cost mean to detect the presence of biomolecules of different shapes, sizes, and their effects on the human being. Ion-sensitive field-effect transistor (IS-FET) is a biological sensor based on the architecture of metal oxide semiconductor field-effect transistor (MOS-FET). The gate terminal is replaced with a hollow space filled by electrolyte solution and reference electrode at the external surface. The biomolecular enzyme in contact with membrane enters in solution induce net DC potential, alter the oxide surface. The alteration of surface puts variation in threshold voltage and maps on the deflection of drain current. ISFET measures the concentration of charged particles (ions) in the solution; variation into ion concentration produces deflection in the drain current. In this work numerical simulation of ISFET is performed with ENBIOS-2D Lab at Nanohub platform with dielectric SiO2, Al2O3, HfO2 with NaCl and KCl in solution. Channel resistance and capacitance with 3-different electric shows a large variation of capacitance, result in threshold voltage i.e. 318.2 mV with SiO2 and 319.2 mV with Al2O3.
Photophysical Investigation of A Benzimidazole Derivative and Its Applications In Selective Detection of Fe3+, Thermosensing and Logic gates.
Authors: Nadgir Aishwarya , Sidarai Ashok H 
Published: May 2021

Abstract
The fluorescence based applications such as chemosensing of Fe3+ ion, temperature sensing, NOR-gate molecular logic operations, and fluorescent ink were achieved using an expired medicine namely Pantoprazole (sensor1) which is a derivative of benzimidazole class. The phenomenon of quenching was a basic principle used in sensing Fe3+. We found that there was a combined effect of dynamic and static processes in quenching of fluorescence of sensor1. To confirm the selectiveness of sensor1, we performed interference experiments with other metal ions. There was no interference between these metal ions and Fe3+. The low LOD value of 1.032µM suggested that the molecule is highly sensitive towards Fe3+. A high quantum yield of 8.087% increased the possibility of using sensor1 for light applications. There was a 2:1 stoichiometric ratio between sensor1 and Fe3+. The FTIR data analysis confirmed the presence of functional groups S = O, C-O-C, etc. The average particle size found with the DLS method was 130.5nm. The zeta potential of -12.7mV indicated that sensor1 is quite stable in solution form. For logic gate application EDTA (Ethylenediaminetetraaceticacid) and Fe3+ were considered as inputs and fluorescence intensity was taken as an output. In thermal sensing application, the high value of activation energy i.e 908meV and relative sensitivity of 1.2% 0C−1 affirmed that sensor1 can be used for thermal applications. The sensor1 was also apt for fluorescent ink application. Hence this investigation deduced that sensor1 can be a potential candidate for such applications over other conventional synthesized fluorescent probes.
A Fatal Case of Streptococcal Toxic Shock Syndrome Developing in the Third Trimester of Pregnancy, China
Authors: Luo Yasha , Zheng Minling , Chen Yanyuan , Gu Chunming , Lv Lijuan , Mu Xiaoping 
Published: May 2021

Abstract
Background
Group A streptococcal (GAS) toxic shock syndrome (TSS) is a rare invasive disease, causing a high risk of maternal and fetal mortality during pregnancy. We report a fatal case of a female caused by GAS-TSS in the third trimester of pregnancy in Guangzhou, China.
Case presentation:
The patient is a 33-year-old female who presented at 37 weeks’ gestation with a history of three hours fever. She underwent an emergency cesarean section due to fetal bradycardia. The neonate survived after an aggressive anti-infection treatment. However, the patient’s condition deteriorated rapidly after the operation and the patient died of disseminated intravascular coagulation and septic shock within 24h after admission. She was finally diagnosed with GAS-TSS. The GAS strains were isolated from two bottles of blood cultures, which confirmed as Streptococcus pyogenes by 16S gene sequencing and identified as serotype M1 by molecular typing.
Conclusions
Dramatical clinical picture and laboratory characters of the pregnant woman presented here might help improve clinicians' awareness and recognition of Streptococcus pyogenes, which could be of great importance for the early diagnosis of GAS- TSS in pregnancy.
Testing the Agreement of Trees with Internal Labels
Authors: Fernández-Baca David , Liu Lei 
Published: May 2021

Abstract
Background: A semi-labeled tree is a tree where all leaves as well as, possibly, some internal nodes are labeledwith taxa. Semi-labeled trees encompass ordinary phylogenetic trees and taxonomies. Suppose we are given a collection P = {T1, T2, . . . , Tk} of semi-labeled trees, called input trees, over partially overlapping sets of taxa. The agreement problem asks whether there exists a tree T , called an agreement tree, whose taxon set is the union of the taxon sets of the input trees such that the restriction of T to the taxon set of Ti is isomorphic to i, for each i ε 1, 2, . . . , k . The agreement problems is a special case of the supertree problem, the problem of synthesizing a collection of phylogenetic trees with partially overlapping taxon sets into a single supertree that represents the information in the input trees. An obstacle to building large phylogenetic supertrees is the limited amount of taxonomic overlap among the phylogenetic studies from which the input trees are obtained. Incorporating taxonomies into supertree analyses can alleviate this issue. Results: We give a O(nk(i∈[k]di + log2(nk))) algorithm for the agreement problem, where n is the total number of distinct taxa in P, k is the number of trees in P, and di is the maximum number of children of a node in Ti. Our computational experience with the algorithm suggests that its performance in practice is much better than its worst-case bound indicates.
Halochromic Cellulose Textile Obtained via Dyeing With Biocolorant Isolated From Streptomyces Sp. Strain NP4
Authors: Kramar Ana Dragan , Ilic-Tomic Tatjana R. , Lađarević Jelena M. , Nikodinovic-Runic Jasmina B. , Kostic Mirjana M. 
Published: May 2021

Abstract
Halochromic (pH-responsive) material was obtained by dyeing functionalized viscose fabric with a crude extract from Streptomyces sp. strain NP4. The functionalization of the pristine fabric before dyeing was performed to make cellulose susceptible to coloration with NP4 extract. Two combined pre-treatment protocols were used, oxidation to obtain dialdehyde cellulose and chitosan deposition onto pristine and oxidized cellulose. Functionalization by both protocols made viscose susceptible to dyeing with the notion that the latter deposition of chitosan produced a darker shade on the material. Dyed fabrics showed visual pH responsiveness in the range pH 4-10, with a color change from pink to red (pH 4 to pH 7) and a major color change from red to blue (pH 7 to pH 10) whereby fabric was tested and could withstand 10 color-changing cycles. Cytotoxicity assay confirmed the non-toxic nature of dyed material, which indicates its possible use as wound dressing’s indicators.
Contrasting effects of the alkaloid ricinine on the capacity of Anopheles gambiae s.l. to transmit Plasmodium falciparum
Authors: Hien Domonbabele François de Sales , Paré Prisca S. L. , Cooper Amanda , Koama Benjamin K. , Guissou Edwige , Yaméogo Bienvenue K. , Yerbanga Rakiswendé S. , Farrell Ian W. , Ouédraogo Jean B. , Gnankiné Olivier , Ignell Rickard , Cohuet Anna , Dabiré Roch K. , Stevenson Philip , Lefèvre Thierry 
Published: May 2021

Abstract
Background: Besides feeding on blood, females of the malaria vector Anopheles gambiae s.l. readily feed on natural sources of plant sugars. The impact of toxic secondary phytochemicals contained in plant-derived sugars on mosquito physiology and on the development of Plasmodium parasites remains elusive. The focus of this study was to explore the influence of the alkaloid ricinine, found in the nectar of the castorbean Ricinus communis, on the mosquito ability to transmit Plasmodium falciparum. Methods: Females of Anopheles gambiae and its sibling species Anopheles coluzzii were exposed to ricinine through sugar feeding assays to assess the effect of this phytochemical on mosquito survival, the level of P. falciparum infection, and the growth rate of the parasite. Results: Ricinine induced a significant reduction in the longevity of both Anopheles species. Ricinine caused acceleration in the parasite growth rate with an earlier invasion of the salivary glands in both species. At a concentration of 0.04 g l-1 in An. coluzzii, ricinine had no effect on mosquito infection, while 0.08 g l-1 ricinine-5% glucose solution induced a 14% increase in An. gambiae infection rate. Conclusions: Overall, our findings reveal that consumption of certain nectar phytochemicals can have unsuspected and contrasting effects on key phenotypic traits that govern the intensity of malaria transmission. Further studies will be required before concluding on the putative role of ricinine as a novel control agent, including the development of ricinine-based toxic and transmission-blocking sugar baits. Testing other secondary phytochemicals in plant nectar will provide a broader understanding of the impact, which plants can have on the transmission of vector-borne diseases.
Construction of Biological Flame Retardant Layer on Cotton Fabric via Photografting of Nucleotide/Amino Acid Monomers
Authors: liu yutong , Wang Xiao , Li Zhenbao , Wei Ju , Du Bing 
Published: May 2021

Abstract
The 5’-adenylicacid (AMP-Na2) is modified to introduce unsaturated double bonds for photografting onto cotton fabrics together with L-cysteine (L-Cys) monomer to prepare synergistic flame-retardant cotton fabrics. The chemical structure of AMP-Na2/L-Cys monomers, the surface morphology, residual carbon morphology, thermal property and flame retardant property of photografted flame retardant cotton fabrics are analyzed. FT-IR and 1H NMR spectra verified the AMP-Na2 and L-Cys monomers with unsaturated double bonds. Scanning electron micrographs revealed the carbon residue of photografted fiber maintains a natural curled and fibers shape. TGA showed the major pyrolysis temperature of photografted cotton fabric declined by 42℃, with the weight loss reduced by 21.6%, proving that good charring effect. The continuous burning and smoldering time of photografted cotton fabric are decreased to 0s. The experimental results indicate that AMP-Na2/L-Cys monomers can reveal good durability and remarkable flame retardancy property to cotton fabrics via facile treatment of photografting.
Mild Progressive Osseous Heteroplasia Overlap Syndrome With PTH and TSH Resistance Appearing During Adolescence and Not Early Childhood
Authors: Ozaki Kayo , Mituboshi Akari , Nagai Masashi , Nishiyama Atushi , Nishimura Gen , Morisada Naoya , Iijima Kazumoto 
Published: May 2021

Abstract
Purpose: Progressive osseous heteroplasia (POH), a genetic disorder, is associated with Albright’s hereditary osteodystrophy (AHO), pseudohypoparathyroidism, and primary osteoma cutis and has common features of superficial ossification and GNAS-inactivating mutations. Disorders due to GNAS­-inactivating mutations are classified as “inactivating parathyroid hormone (PTH)/PTHrP signaling disorder type 2.” This study reports a case of mild POH overlap syndrome to improve understanding of genotype–phenotype correlations.Methods: A 13-year-and-6-month-old Japanese boy was referred to our hospital with a chief complaint of the lower limb length difference. He underwent clinical, biochemical, radiological, and genetic studies.Results: He showed sporadic GNAS mutation, deep ectopic ossification, small for gestational age (SGA), congenital tooth defect, and lack of AHO features; he met the diagnostic criteria for POH, and mild PTH and TSH resistance was detected. He had constant hyperphosphatasemia and hypocalciuria. At the age of 10 years, he occasionally experienced high iPTH levels. The pituitary stimulation test showed a normal response of all hormones at 3 years of age, but TSH response was decreased (previously 0.770, peak value 4.144 μIU/mL) in the TRH loading test at age 13 years and 6 months. DNA analysis showed a heterozygous p.D189MfsTer14 mutation of GNAS. The parents did not carry this mutation.Conclusion: We report a rare case of POH overlap syndrome with PTH/TSH resistance that appeared in adolescence rather than early childhood. Cases diagnosed with POH in early childhood also require reassessment during adolescence. Further studies of the GNAS heterozygous mutation p.D189MfsTer14 may reveal factors involved in POH overlap syndrome.
An Adaptive Trajectory Tracking Controller of a Multi-joint Snake Robot Considering Non-holonomic Constraints
Authors: Li Dongfang , Wang Chao , Deng Hongbin , Huang Jie 
Published: May 2021

Abstract
Multi-joint snake robot is a vital reconnaissance, surveillance and attack weapon in national defence and military in the future. To study the trajectory tracking problem of a multi-joint snake robot with high redundancy and multi-degree of freedom in the plane, an adaptive trajectory tracking controller of a multi-joint snake robot considering non-holonomic constraints is proposed in this paper. The adaptive trajectory tracking controller replaces unknown parameters in the environment wi t h estimated values, which effectively solves the negative effects caused by uncertain and time-varying environmental parameters in the process of the robot movement and realizes the stability of the controller. Firstly, a new dynamical model of a multi-joint snake robot is established through coordinate transformation. Secondly, the control objective of the controller of the multi-joint snake robot is established. Thirdly, the proposed controller of the multi-joint snake robot is designed by the Backsteppi n g method to realize the control of the joint angle tracking error, link angle tracking error, actuator torque error and motion speed error of the robot. Then, a suitable Lyapunov function is found to verify the stability of the controller. Finally, through the MATLAB simulation and prototype experiment, the motion process of the multi-joint snake robot is observed, the trajectory tracking performance of the robot is analyzed, and the effectiveness of the adaptive trajectory tracking controller is verified.
Cervical Ripening With Multiple Medical or Combined Induction Methods: Risks of Subsequent Preterm Birth in Nulliparous Women
Authors: Farago Naama , Ginsberg Yuval , Bachar Gal , Beloosesky Ron , Vitner Dana , Weiner Zeev , Ganem Nadir , Khatib Nizar 
Published: May 2021

Abstract
Objectives: Cervical ripening is one of the most frequently used procedures in modern obstetrics; it can be conducted with mechanical (single or double balloon), medical (PGE2), or combinations of both methods. We aimed to determine the impact of combined methods on the risk of preterm birth in subsequent pregnancy, in nulliparous women. Methods: A retrospective cohort study of term singleton gestations in nulliparous women, who were induced by mechanical, medical, or combined methods for any indication, managed at one tertiary medical center from 2019 to July 2019, and had their subsequent second birth in our institution. Study groups were compared to a control group of nulliparous women not induced. The primary outcome was risk of preterm labor in the second consecutive birth. Secondary outcomes included maternal and fetal complications, postpartum hemorrhage, chorioamnionitis, mode of delivery, and fetal Apgar score. Results: Our cohort included 1277 nulliparous women who underwent cervical ripening with mechanical, medical, or combined methods, and a subsequent singleton live birth in our institution. Our study group consisted of 942 women induced by one dose of PGE2, 248 women induced by multiple doses of PGE2 or combined methods, and 87 women induced by mechanical method. The study group was matched to 3903 women in the control group. Demographic data of the four groups were identical, including maternal age, body mass index, and maternal diseases. The rates of spontaneous pre-term birth in the subsequent births, defined as birth at < 37 weeks, did not differ among the four groups (4.9% in single dose group, 2% in multiple induction group, 6.9% in mechanical induced group, and 4.3% in the control group). Moreover, the rates of spontaneous early preterm birth at < 34 weeks did not differ among the groups. Conclusions: Cervical ripening with combined methods or multiple medical doses did not increase the rate of subsequent spontaneous preterm births in nulliparous women. The rate of maternal or fetal complications was identical in our study and control group.
Patterns of pre-operative opioid use affect the risk for complications after total joint replacement
Authors: Ravi Bheeshma , Pincus Daniel , Croxford Ruth , Leroux Timothy , Paterson Michael , Hawker Gillian , Redelmeier Donald A. 
Published: May 2021

Abstract
Background Preoperative opioid use has been shown to increase the risk for complications following total joint arthroplasty (TJA); however, these studies have not always accounted for differences in co-morbidities and socio-demographics between patients that use opioids and those that do not. They have also not accounted for the variation in degree of pre-operative use. The objective of this study was to determine if preoperative opioid use is associated with risk for surgical complications after TJA, and if this association varied by degree of use. Methods Population-based retrospective cohort study. Older adult patients undergoing primary TJA of the hip, knee and shoulder for osteoarthritis between 2002 and 2015 in Ontario, Canada were identified. Using accepted definitions, patients were stratified into three groups according to their preoperative opioid use: no use, intermittent use and chronic use. The primary outcome was the occurrence of a composite surgical complication (surgical site infection, dislocation, revision arthroplasty) or death within a year of surgery. Intermittent and chronic users were matched separately to non-users in a 1:1 ratio, matching on TJA type plus a propensity score incorporating patient and provider factors. Results Overall, 108,067 patients were included in the study; 10% (N=10,441) used opioids on a chronic basis before surgery and 35% (N=37,668) used them intermittently. After matching, neither intermittent nor chronic pre-operative opioid use were associated with an increased risk for complications after TJA. Conclusions Overall, less than half of patients undergoing TJA used opioids in the year preceding surgery; the majority used them only intermittently. Pre-operative opioid use is not associated with an increased risk for complications after TJA.