bluuebunny/crossref_metadata_2025_split huggingface dataset:
Erectile Dysfunction and Decreased Libido in Klinefelter Syndrome: A Prevalence Meta-Analysis and Meta-Regression Study
Authors: Barbonetti Arcangelo , D’Andrea Settimio , Vena Walter , Pizzocaro Alessandro , Rastrelli Giulia , Pallotti Francesco , Condorelli Rosita , Calogero Aldo E. , Pasquali Daniela , Ferlin Alberto , Foresta Carlo , Jannini Emmanuele A. , Maggi Mario , Lenzi Andrea , Pivonello Rosario , Isidori Andrea , Garolla Andrea , Francavilla Sandro , Corona Giovanni 
Published: May 2021

ABSTRACTBackgroundOnly few studies have assessed sexual dysfunction in men with Klinefelter syndrome (KS).AimTo define pooled prevalence estimates and correlates of erectile dysfunction (ED) and decreased libido (DL) in KS.MethodsA thorough search of Medline, Embase and Web of Science was performed to identify suitable studies. Quality of the articles was scored using the Assessment Tool for Prevalence Studies. Data were combined using random effect models and the between-studies heterogeneity was assessed by the Cochrane’s Q and I2. The sources of heterogeneity were investigated by meta-regression and sub-group analyses. Funnel plot, Begg’s rank correlation and trim-and-fill test were used to assess publication bias.Main Outcome MeasureThe pooled prevalence of ED and DL in KS as well as 95% confidence intervals (CIs) were estimated from the proportion of cases of sexual dysfunction and the sample size. Variables that could affect the estimates were identified by linear meta-regression models.RESULTSSixteen studies included collectively gave information about ED and DL in 482 and 368 KS men, respectively, resulting in a pooled prevalence of 28% (95% CI: 19%–36%) for ED and 51% (95% CI: 36%–66%) for DL, with a large heterogeneity. The trim-and-fill adjustment for publication bias produced a negligible effect on the pooled estimates. At the meta-regression analyses, a higher prevalence of ED was significantly associated with an older age but not with lower testosterone levels. In series with a mean age &gt;35 years, the ED prevalence estimate increased up to 38% (95% CI: 31%–44%) with no heterogeneity (I2=0.0%, P=0.6). On the contrary, the prevalence of DL increased significantly as testosterone levels decreased, without a significant relationship with age.Clinical ImplicationsWhile DL would largely reflect an androgen deficiency, in older men with KS, erectile function should be assessed irrespective of testosterone levels.Strength & LimitationsThis is the first meta-analysis defining pooled prevalence estimates and correlates of ED and DL in KS. Nevertheless, caution is required when interpreting results, due to the high risk of bias in many studies, as well as the dearth of data about psychosocial and/or psychosexological variables and age at the diagnosis.CONCLUSIONSED and DL represent common clinical complaints in KS. While the prevalence of ED would increase with age, DL gets more common as serum testosterone decreases. Further studies are warranted to elucidate the pathogenetic mechanism(s) underlying the age-dependent increase in the prevalence of ED, apparently unrelated to the androgenic status.
Machine Learning Arrives in Archaeology
Authors: Bickler Simon H. 
Published: May 2021

OverviewMachine learning (ML) is rapidly being adopted by archaeologists interested in analyzing a range of geospatial, material cultural, textual, natural, and artistic data. The algorithms are particularly suited toward rapid identification and classification of archaeological features and objects. The results of these new studies include identification of many new sites around the world and improved classification of large archaeological datasets. ML fits well with more traditional methods used in archaeological analysis, and it remains subject to both the benefits and difficulties of those approaches. Small datasets associated with archaeological work make ML vulnerable to hidden complexity, systemic bias, and high validation costs if not managed appropriately. ML's scalability, flexibility, and rapid development, however, make it an essential part of twenty-first-century archaeological practice. This review briefly describes what ML is, how it is being used in archaeology today, and where it might be used in the future for archaeological purposes.
Synthesis of an active flutter suppression system in the transonic domain using a computational model
Authors: Vepa R. , Kwon J.R. 
Published: May 2021

ABSTRACTControl laws for implementing active flutter suppression are generally derived from linear aeroelastic models. In this paper, families of control laws for implementing an active flutter suppression system were initially designed using linearised aeroelastic models based on the doublet lattice method after ignoring the aerodynamic loads associated with relatively faster time scales. Using these preliminary sets of control laws and the nonlinear transonic small disturbance theory, near-optimum control laws were chosen in the transonic domain to maximally increase the flutter speed of a typical aircraft wing by at least 16% or more. Thus it is shown that it is feasible to systematically design near-optimal control laws for active flutter suppression using computational models in transonic flow. The doublet lattice method coupled with the zeroth-order matrix Padé approximant provided the fastest method for synthesising a large number of preliminary control laws. The methodology was successfully demonstrated by applying it to two benchmarking examples.
What’s In the Manuscripts of Timbuktu? A Survey of the Contents of 31 Private Libraries
Authors: Stewart Charles C. 
Published: May 2021

AbstractThe Arabic manuscripts of Timbuktu have received considerable publicity during the past 25 years, yet their contents remain largely unknown. Since 2012, an inventory of nearly 350,000 Timbuktu manuscripts in private libraries has been underway, and the contents of those libraries are now accessible in the West African Arabic Manuscript Database (WAAMD). This analysis examines 31 of the 35 libraries and in addition to reporting on their contents, notes challenges in accessing incompletely identified works, and compares the manuscripts with other West African collections.
Both Feminist and Practical Politics: The Incorporation of Infertility Treatment into Family Planning in Britain, 1930s–1950s
Authors: Beers Laura 
Published: May 2021

AbstractIn the mid-twentieth century, the Family Planning Association emerged in Britain as one of the largest providers of infertility diagnosis for men and women. In the early years of the century, women were coming to birth control centers seeking cures for their childlessness, well before those centers began officially offering infertility investigation and treatment. What changed by mid-century was the emergence of a determination not only to welcome infertility patients at birth control clinics but to establish the clinics as centers for infertility research and care. Beginning in the late 1930s, eugenicists concerned with the impact of population decline on the social acceptability of birth control formed an alliance with feminist medical professionals determined both to empower women in involuntarily childless marriages to understand and address the causes of their infertility and to shift the paradigm of infertility treatment away from its over-focus on the female body. This political marriage of convenience gave birth to a large-scale movement to diagnose both male and female infertility through the auspices of the Family Planning Association. The organization's infertility program, in turn, spurred the development of infertility as a field of medical research in postwar Britain and encouraged the expansion of National Health Service provision of infertility care.
Occurrence of global instability in hypersonic compression corner flow
Authors: Hao Jiaao , Cao Shibin , Wen Chih-Yung , Olivier Herbert 
Published: May 2021

Hypersonic flow over a two-dimensional compression corner with a Mach number of 7.7 and unit Reynolds number of 4.2 × 106m−1is numerically investigated. Special emphasis is given to the onset of global instability with respect to three-dimensional perturbations. Global stability analysis is performed for various ramp angles and wall temperatures. It is found that the shock-induced separated flow system becomes unstable when the ramp angle is beyond a certain value. The critical ramp angle increases slightly with the wall temperature, although the length of the separation region is significantly enlarged. The global instability is shown to be closely linked with the occurrence of secondary separation beneath the primary separation bubble. A criterion is established based on a scaled ramp angle defined in the triple-deck theory to predict the global stability boundary, which depends on the free-stream conditions and geometries only.
Genes go digital: Mendelian Inheritance in Man and the genealogy of electronic publishing in biomedicine
Authors: McGovern Michael F. 
Published: May 2021

AbstractMendelian Inheritance in Man (MIM), a computerized catalogue of human genetic disorders authored and maintained by cardiologist and medical genetics pioneer Victor A. McKusick, played a major part in demarcating between a novel biomedical science and the eugenic projects of racial betterment which existed prior to its emergence. Nonetheless, it built upon prior efforts to systematize genetic knowledge tied to individuals and institutions invested in eugenics. By unpacking the process of digitizing a homespun cataloguing project and charting its development into an online database, this article aims to illuminate how the institution-building efforts of one individual created an ‘information order’ for accessing genetic information that tacitly shaped the norms and priorities of the field toward the pursuit of specific genes associated with discernible genetic disorders. This was not by design, but rather arose through negotiation with the catalogue's users; it accommodated further changes as biomedical research displaced the Mendelian paradigm. While great effort was expended toward making sequence data available to investigators during the Human Genome Project, MIM was largely taken for granted as a ‘legacy system’, McKusick's own labour of love. Drawing on recent histories of biomedical data, the article suggests that the bibliographical work of curation and translation is a central feature of value production in the life sciences meriting attention in its own right.
THE FAMILY TRADITIONS OF THE GENS MARCIA BETWEEN THE FOURTH AND THIRD CENTURIES b.c.
Authors: Morelli Davide 
Published: May 2021

AbstractIn the mid fourth century b.c. some Roman gentes drew on a Pythagorean tradition. In this tradition, Numa's role of Pythagoras’ disciple connected Rome (and the gentes) with Greek elites and culture. The Marcii, between 304 and 300 b.c., used Numa's figure, recently reshaped by the Aemilii and the Pinarii for their propaganda, to promote the need for a plebeian pontificate. After the approval of the Ogulnium plebiscite (300 b.c.), the needs for this kind of propaganda fell away. When Marcius Censorinus became censor, Numa's pontificate was no longer relevant for promoting the gens. For this reason, the Marcii used another genealogy for similar propagandistic effect: the figure of Marsyas, a symbol of plebeian ideals.
NOTE ON THE p-DIVISIBILITY OF CLASS NUMBERS OF AN INFINITE FAMILY OF IMAGINARY QUADRATIC FIELDS
Authors: KRISHNAMOORTHY SRIlAKSHMI , PASUPULATI SUNIL KUMAR 
Published: May 2021

AbstractFor any odd prime p, we construct an infinite family of imaginary quadratic fields whose class numbers are divisible by p. We give a corollary that settles Iizuka’s conjecture for the case n=1 and p>2.
Fertility intention-based birth forecasting in the context of China’s universal two-child policy: an algorithm and empirical study in Xi’an City
Authors: Liu Jianghua , Zhang Lianchao 
Published: May 2021

AbstractAfter a universal two-child policy was introduced in China in 2016, studies have been published using women’s fertility intentions to forecast future births; however, the recommended algorithms need to be improved. In this study, an algorithm based on the method of limiting factors is developed to retrospectively forecast annual births in Xi’an City in the first three years of policy implementation, i.e. 2016–2018. The 2015 Xi’an Fertility Survey (sample: 560 one-child mothers) showed that 17% of mothers intended to have a second child, 30% were undecided and 53% did not intend to do so at the end of 2015. The low forecast variant based on the updated algorithm indicates that there would be a baby boom in 2016–2018, but the annual births would increase by 13% at most. The forecasting results are basically consistent with the official reports on annual births. This study emphasizes the importance of appropriately adjusting all fertility intentions in birth forecasting, helps to understand women’s fertility behaviour and evaluate the effects of implementing the universal two-child policy, and has important implications for China’s population and family planning work.
Becoming Peter Fitzpatrick (1941–2020)
Authors: Sugarman David 
Published: May 2021

AbstractThis paper examines the reciprocal interplay between Peter Fitzpatrick's life and work, between significant people, events, ideas and values, and the ways in which he made and re-made himself. It illuminates Peter's struggle, especially from the 1990s onwards, to place ethics centre stage in both life and law. Drawing on archival and secondary research, including interviews with Peter's family, former colleagues and students, this contribution to legal life writing adds to what we already knew about Peter and his scholarship. It assesses and clarifies his key ideas and their intersection with his ethics and lived experiences. It is hoped that the paper will encourage those who are less familiar with Peter's work, or who find his writing daunting, to tackle it anew and appreciate its significance.
Myth and concealment at colonial law's foundations
Authors: Pavlich George 
Published: May 2021

AbstractThis paper provides an engagement with, and highlights the depth of, Peter Fitzpatrick's careful examination of myths that grounded modern law and its colonial instances. That grounding is shown to be premised on a concealment of basic contradictions behind fictions of a unified law, even though it only appears through negations of others. Intersecting patterns of marginalisation are shown to be constitutive of modern and colonial law, so it is not surprising that current protests should address a basic exclusionary racism that Fitzpatrick's work signalled. It concludes with some reflections on what his work might mean for three current debates.
A concise note on Peter Fitzpatrick's ‘Racism and the innocence of law’
Authors: Tuitt Patricia 
Published: May 2021

AbstractI have long felt that Peter Fitzpatrick's 1987 paper, ‘Racism and the innocence of law’, should be closely studied by all law students during, or shortly after, their induction to the study of law. These concise notes on the paper are written primarily in tribute to a friend, colleague and mentor but, in writing them, I hope also to demonstrate how this early instance of a theory about how law is intertwined in racial capitalism could be taught in those law schools that harbour ambitions to be not only critical, but also decolonial. Inevitably, in such a short piece, choices have had to be made about which aspects of the paper to foreground and which to leave out entirely. I trust that my decision to focus on those aspects that can be more readily comprehended by a student with limited knowledge of legal theory and substantive fields of law will not be thought to have unduly watered down its meaning.
Cuboidal quad-port UWB-MIMO antenna with WLAN rejection using spiral EBG structures
Authors: Modak Sumon , Khan Taimoor 
Published: May 2021

AbstractThis study presents a novel configuration of a cuboidal quad-port ultra-wideband multiple-input and multiple-output antenna with WLAN rejection characteristics. The designed antenna consists of four F-shaped elements backed by a partial ground plane. A 50 Ω microstrip line is used to feed the proposed structure. The geometry of the suggested antenna exhibits an overall size of 23 × 23 × 19 mm3, and the antenna produces an operational bandwidth of 7.6 GHz (3.1–10.7 GHz). The notched band characteristic at 5.4 GHz is accomplished by loading a pair of spiral electromagnetic bandgap structures over the ground plane. Besides this, other diversity features such as envelope correlation coefficient, and diversity gain are also evaluated. Furthermore, the proposed antenna system provides an isolation of −15 dB without using any decoupling structure. Therefore, to validate the reported design, a prototype is fabricated and characterized. The overall simulated performance is observed in very close agreement with it's measured counterpart.
Neurodevelopmental assessment of infants born to mothers with hypertensive disorder of pregnancy at six months of age
Authors: Sala Marisa E. , Romero M. Florencia , Romero Anabella , Fasano M. Victoria , Varea Ana M. , Carrera Patricia , Salazar Martín R. , Espeche Walter G. , González Horacio F. 
Published: May 2021

AbstractInfant neurodevelopment is a complex process which may be affected by different events during pregnancy, such as hypertensive disorders of pregnancy (HDP). We conducted a prospective cohort study to compare the prevalence of neurodevelopmental disorders in infants born to mothers with and without HDP at six months of age. Participants attended the Health Observatory of Instituto de Desarrollo e Investigaciones Pediátricas “Prof. Dr. Fernando E. Viteri” during 2018 and 2019. Infant neurodevelopment was assessed with the Bayley Scales of Infant and Toddler Development—Third Edition (Bayley-III). Data were analyzed using Chi-square, Student’s t-test and Mann–Whitney test. Of the 132 participating infants, 68 and 64 were born to mothers with and without HDP, respectively. At six months, the prevalence of risk of neurodevelopmental delay was significantly higher in infants born to mothers with than without HDP (27.9% vs. 9.4%; p = 0.008) (odds ratio, 3.71; 95% confidence interval, 1.30; 12.28). In conclusion, infants born to mothers with HDP had three times increased risk of neurodevelopmental delay at six months of age.
Nationalism or Geopolitics: The Rise of Guerillas and Patterns of Military Conflict during the Expansion of the Ili Rebellion, 1944–46
Authors: Wei Zikui 
Published: May 2021

AbstractThis article investigates the Ili Rebellion in Xinjiang (1944–49). Relying primarily on Chinese sources, the author identifies variations in the rise and fate of non-Han ethnic guerillas, and the patterns of military conflict in different regions during the expansionist stage of the Ili Rebellion from 1944 to 1946. The article argues that neither a nationalist nor a geopolitical explanation adequately account for such variations. Rather, the overlapping and intersecting geopolitical influence (both the Soviet Union and the two Chinese regimes) as well as local conditions (including local ethnic composition and social structure) explain such patterns. Finally, this article discusses broader implications of the role of nationalism and geopolitics in revolutions in small and dependent states.
Moho Depth Estimation Beneath Tibet From Satellite Gravity Data Based on a Condensation Approach
Authors: Chen Wenjin , Tenzer Robert , Xu Xinyu , Wang Shuai , Wang Bin 
Published: May 2021

AbstractWe develop an algorithm for a Moho depth recovery from gravity and gravity gradiometry data and apply this method to estimate the Moho depth beneath the Tibetan Plateau. The basic idea of this algorithm is to describe mathematically the Moho depth undulations in terms of a condensation layer with respect to a mean Moho depth, instead of applying more commonly used isostatic compensation schemes. Expressions that functionally relate gravity field quantities with a (Moho) condensation layer are derived in spectral and spatial domains. The main advantage of this algorithm is that a functional relation between gravity field quantities and surface density anomalies, and consequently Moho depth undulations, has a linear form. The proposed algorithm is tested using satellite gravity and gravity gradiometry data. The Moho depth (taken with respect to the geoid surface) estimates obtained based on applying this algorithm are validated against global and regional seismic Moho results at the study area of Tibet. We also compare the result with the corresponding Moho depth estimates obtained by applying the Parker–Oldenburg and Vening Meinesz–Moritz (VMM) methods. The validation shows that results from all three gravimetric methods are similar, and they also closely agree with a regional seismic Moho model. Nevertheless, the VMM method and our algorithm in this comparison overperform the Parker–Oldenburg's method. The analysis of results also reveals that the newly developed algorithm provides better result (in terms of the RMS fit with a regional seismic Moho model) when applied for a Moho determination from gravity gradiometry instead of gravity data.
Localized Backarc Extension in an Overall Compressional Setting During the Assembly of Nuna: Geochemical and Isotopic Evidence From Orosirian (1883–1848 Ma) Mafic Magmatism of the Aillik Group, Labrador, Canada
Authors: Hinchey A. M. 
Published: May 2021

AbstractBimodal volcanism occurs in a range of extensional environments that are characterized by distinctive but overlapping, lithogeochemical and isotopic signatures and lithological assemblages. Where basaltic magmatism is associated with ferroan (A‐type) rhyolites, it is typically the lithogeochemistry and isotopic systematics of the basaltic rocks that are the most beneficial in constraining the tectonic evolution. This study presents geochemical and isotopic data from mafic volcanic rocks of the bimodal Aillik Group, that formed during the assembly of the Paleoproterozoic supercontinent Nuna. Lithogeochemical signatures define two suites. Suite 1 samples have N‐MORB (Normal‐Mid‐Ocean Ridge Basalt) chemical affinities such as flat HREE, and smooth but flat LREE and have εNd(t = 1860 Ma) values between +2.8 and +4.8. Suite 2 samples typically have compositions between N‐MORB and IAT (Island Arc Tholeiites) basalts, with variable REE patterns ranging from IAT to OIB (Ocean Island Basalt). The basalts display moderately developed subduction zone signatures, such as negative Nb and Ti, and have εNd(t = 1860 Ma) ranging from −3.4 to +2.2. Geochemical variability within the Aillik Group mafic rocks is explained by processes active in arc settings and involves mixing between depleted mantle components with variable contributions from crustal and subducted‐slab sources. Coupled with field evidence, the geochemical and isotopic data support emplacement of the basalt in an extensional, backarc basin setting. This backarc basin formed due to localized extension during Nuna assembly. The Makkovik Province preserves a complex orogen characterized by multiple diachronous, compressional, and extensional events along a long‐lived active margin of the Archean North Atlantic Craton.