bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geometrical properties of underutilized cereal varieties of Himalayan origin for the development of future processing equipments.
Authors: Jhan Faiza , Gani Adil , Shah Asima 
Published: October 2021

Abstract
This paper presents the database of physical and engineering characteristics of grains and flours of five underutilized cereal varieties viz sorghum, buck wheat, pearl millet, proso millet and barley of Himalayan origin. The results revealed a significant difference in width, length and breadth of these cereals. The sphericity value of cereal grains showed significant difference (p≤0.05) in the range 97.42 to 137.25.84% which was found to be highest for sorghum grain while as aspect ratio was found highest for proso millet grain. The static coefficient of friction samples was found maximum on corrugated board for the flour and grain. The hausner ratio and compressibility index indicated poor flowability of the sorghum flour. The bulk density, tapped density and porosity values of cereal grains varied significantly for cereal grains as well as flours. ATR-FTIR (attenuated total reflectance-Fourier transform infrared spectroscopy) confirmed the different types of linkages present in the flour samples found within the absorption bands of 3500-993 cm-1.
Document Localization in Images Taken by Smartphones Using a Fully Convolutional Neural Network
Authors: Baniadamdizaj Shima , Soheili Mohammadreza , Mansouri Azadeh 
Published: October 2021

Abstract
Today integration of facts from virtual and paper files may be very vital for the expertise control of efficient. This calls for the record to be localized at the photograph. Several strategies had been proposed to resolve this trouble; however, they may be primarily based totally on conventional photograph processing strategies that aren't sturdy to intense viewpoints and backgrounds. Deep Convolutional Neural Networks (CNNs), on the opposite hand, have demonstrated to be extraordinarily sturdy to versions in history and viewing attitude for item detection and classification responsibilities. We endorse new utilization of Neural Networks (NNs) for the localization trouble as a localization trouble. The proposed technique ought to even localize photos that don't have a very square shape. Also, we used a newly accrued dataset that has extra tough responsibilities internal and is in the direction of a slipshod user. The end result knowledgeable in 3 exclusive classes of photos and our proposed technique has 83% on average. The end result is as compared with the maximum famous record localization strategies and cell applications.
Characteristics of genitourinary tuberculosis in Sri Lanka: A retrospective cohort study
Authors: Jayarajah Umesh , Gunawardena Milan , Willaraarachchi Munipriya , Chandrasiri Shirani , Udayakumaran Perumal , Sosai Cherine , Abeygunasekera Anuruddha 
Published: October 2021

Abstract
BackgroundAlthough genitourinary Tuberculosis (GUTB) is the second commonest source of extrapulmonary TB in most countries, the reported rate of GUTB in Sri Lanka remains very low. Furthermore, the characteristics of GUTB in Sri Lanka have not been published due to paucity of data. Therefore, we aimed to study the clinical and imaging characteristics, treatment modalities and outcomes of GUTB in Sri Lanka. MethodsA retrospective analysis was performed based on patients treated by a single urological surgeon in two consecutive centres over a period of 21 years. All patients (n=82, males = 45 (54.9%), median age: 51 years; range: 26 - 75) with a microbiological and/or histological diagnosis of GUTB were included. Median duration of follow-up was 24 months (range: 6- 96). Data were obtained from direct patient interview, hospital notes and clinic files. ResultsCommonest prominent symptoms at presentation included haematuria (n=13, 15.8%) and scrotal manifestations (n=12, 14.6%). Mantoux was either positive (>10mm) (n=62/70) or equivocal (>5mm) (n=8/70). Erythrocyte sedimentation rate (ESR) was available in 69 patients and was >30 in 54 (78.3%) patients. Chest x-ray and x-ray kidney-ureter-bladder (KUB) abnormalities were detected in 9 (11%) and 6 (7.3%) respectively. CT-urography was performed in 72 patients and abnormalities were detected in 57 (79%) patients. Forty-two patients underwent a cystoscopy and 73.8% (n=31) had abnormal findings. Microbiological diagnosis was feasible in 42 (51.2%) and rest were diagnosed histologically. Commonest organs involved were kidney (64.6%, n=53), ureters (51.2%, n=42), bladder (43.9%, n=36) and testis/epididymis (14.6%, n=12). One patient had prostate TB. All were treated primarily with anti-TB drugs however, 50 (61%) had indications for some form of therapeutic intervention. The majority of interventions were reconstruction surgeries (n=20, 24.4%) followed by excision surgeries (n=19, 23.2%) and drainage procedures (n=11, 13.4%).Seven patients developed serious adverse reactions to anti-TB drugs. Five patients developed a thimble bladder and 3 patients developed end-stage renal failure. Two patients had relapse of infection. ConclusionCT-Urography, cystoscopy and histopathology are essential adjuncts to diagnose GUTB. Most ureteric strictures, non-functioning kidneys and epididymal masses needed surgical treatment. Long-term follow up is essential to detect progressive renal dysfunction.
The Role of Institutional Quality in Oil Price-Unemployment Nexus in African and Asian Oil-Exporting Countries
Authors: Raifu Isiaka Akande 
Published: October 2021

Abstract
This study adopts panel OLS and panel ARDL to examine the role of institutional quality in institutional quality in oil price-unemployment nexus in African and Asian oil-exporting countries. The POLS results reveal that an increase in oil price does not reduce unemployment in African oil-exporting countries whereas it reduces unemployment in Asian oil-exporting countries. However, interaction of oil price with institutional quality variables such as democratic accountability and rule of law leads to reduction of unemployment in African oil-exporting counties while the interaction of control of corruption and government stability with oil price leads to a further reduction in unemployment in Asian oil-exporting countries. The panel ARDL results, however, show that an increase in oil price leads to a reduction in unemployment in African oil-exporting countries only in the short run while it leads to a reduction in unemployment in Asian oil-exporting countries only in the long run. The effect of the interaction of institutional quality with the oil price, even though slightly changes when PARDL is employed, it largely remains ditto when compared with POLS. Given our results, we conclude that each of the oil-exporting countries needs to strengthen some aspects of their institutional quality apparatuses to ensure that an increase in the oil price brings about the desirable effect on unemployment. Precisely, the fight against corruption and government instability must be given the utmost attention in African oil-exporting countries while the rule of law and democratic accountability must be prioritised in Asian oil-exporting countries.JEL Classifications: C33; E24; L71; O17
Photonic microwave and RF programmable true time delays for phased array antennas using a soliton crystal Kerr micro-comb source
Authors: Moss David 
Published: October 2021

Abstract
We demonstrate significantly improved performance of a microwave true time delay line based on an integrated optical frequency comb source. The broadband micro-comb (over 100 nm wide) features a record low free spectral range of 49GHz, resulting in an unprecedented record high channel number (81 over the C band) – the highest number of channels for an integrated comb source used for microwave signal processing. We theoretically analyze the performance of a phased array antenna and show that this large channel count results in a high angular resolution and wide beam steering tunable range. This demonstrates the feasibility of our approach as a competitive solution towards implementing integrated photonic true time delays in radar and communications systems.
SHiMMer: Privacy-Aware Alignment of Genomic Sequences with Secure and Efficient Hidden Markov Model Evaluation
Authors: Kim Miran , Song Yongsoo , Jiang Xiaoqian , Harmanci Arif 
Published: October 2021

Abstract
As the cost of DNA sequencing is decreasing, personal genomic data is becoming more abundant. Genomic data is known to be very identifying; even a few genetic mutations can identify an individual. Therefore, leakage of genetic information and the associated metadata create privacy risks. While these risks are well-known, most of the basic methods are not privacy-aware. One of these fundamental methods is the Hidden Markov Models (HMMs), which are especially important for comparative genomics because genetic data are sequential in nature, e.g., DNA/RNA nucleotides sequences and protein residues. HMMs are used mainly for comparing and aligning DNA/RNA and protein sequences, such as viral genomes or gene sequences, whereby similar portions of sequences are identified and they are defined to be conserved throughout evolution, whereas non-matching portions of the sequences indicate a divergence. HMM-based inference of sequence alignment is therefore a vital component of sequence analysis. Here, we describe SHiMMer, Secure HMM evaluation method that can guarantee cryptographic security while HMMs are used for sequence comparison. We used simulated data for alignment of genomic sequences to demonstrate that SHiMMer can perform sequence alignment efficiently. We present the scaling of time/memory requirements with increasing numbers of alignment states and lengths of sequences.
bridges over the river Kei
Authors: Martinson William 
Published: October 2021

The article is the outcome of the author's long-standing interest in the number and variety of bridges that were built within a short section of the Great Kei River at Victoria Drift - in close proximity to the village of Komgha - over a 100-year period. The particular bridges under scrutiny - with their dates of construction - are as follows:

Temporary Military Bridge, 1877 (no longer extant)
Lattice Girder Wagon Bridge, 1879
Timber Railway Bridge, 1905 (only foundations remaining)
Relocated Lattice Girder Railway Bridge, 1948
N2 SANRAL Concrete Bridge, 1977.
PERCEPÇÕES DE GESTORES SOBRE AS AÇÕES DE EDUCAÇÃO ALIMENTAR E NUTRICIONAL NA ESCOLA
Authors: Soder Taís Fátima , Benetti Fábia , Deon Rúbia Garcia , Volkweis Dionara Simoni Hermes , Weyh Cênio Back 
Published: October 2021

A Educação Alimentar e Nutricional (EAN) representa uma das mais importantes práticas e estratégias de incentivo à incorporação de hábitos alimentares saudáveis de caráter emancipatória na vida das novas gerações. Nesta perspectiva, o estudo objetivou identificar a percepção de gestores sobre a EAN no âmbito escolar. Trata-se de uma investigação qualitativa com abordagem hermenêutica. Quanto aos fins, envolve a pesquisa descritiva exploratória e quanto aos meios, pesquisa de campo. Os dados foram coletados através de entrevistas gravadas com secretários de educação e nutricionistas, responsáveis técnicos pela merenda escolar (12 entrevistados) de alguns municípios do Médio e Alto Uruguai/RS. A escolha da amostra é considerada probabilística e aleatória simples. A análise de conteúdo foi escolhida como estratégia para discussão dos dados obtidos na pesquisa de campo. Quando indagados sobre a percepção da EAN na escola, os entrevistados ressaltaram as essas ações como práticas reflexivas, promotoras de saúde, formadoras de atores e da autonomia alimentar. Sobre o que poderia ser feito, destacaram a necessidade de incentivo constante, de projetos integradores, capacitação de professores sobre a temática e, ainda, a importância do trabalho de EAN no ambiente familiar. Conclui-se que a escola se apresenta como ambiente favorável para o desenvolvimento de estratégias de EAN problematizadoras, dialógicas e, por considerem a realidade local, fomentando para a necessidade de gestão e adequado planejamento destas ações.
ELABORAÇÃO E VALIDAÇÃO DE MATERIAL DIDÁTICO PARA ESCOLHA DE EXCIPIENTES DE CÁPSULAS PREPARADAS MAGISTRALMENTE
Authors: Gemeinder Adriana Carrer Stefanini , Casagrande Vanessa , Pinheiro Osni Lázaro 
Published: October 2021

RESUMO
Os excipientes são componentes fundamentais de uma preparação farmacêutica, estabilizando o princípio ativo, favorecendo sua solubilidade durante o processo de preparação e sua absorção após administração. Entretanto, a escolha dessas substâncias deve ser um processo criterioso, pois podem interferir na biodisponibilidade dos fármacos e causar efeitos colaterais. O objetivo deste estudo foi elaborar e validar um material educativo para auxiliar os farmacêuticos na escolha dos excipientes adequados para a preparação de cápsulas magistrais. Inicialmente foi elaborado um questionário com assertivas para definição dos temas que poderiam compor o material educativo sobre excipientes. Este questionário foi encaminhado para um grupo de juízes, constituídos por farmacêuticos com experiência na área de farmacotécnica. Pautado nas avaliações foi elaborado o material educativo sobre excipientes, que foi novamente enviado aos juízes para validação. As avaliações dos juízes apoiaram a confecção de um material educativo sobre excipientes para preparação de cápsulas seguindo os critérios do Sistema de Classificação Biofarmacêutica. O material foi validado, alcançando o índice de 70% de concordância proposto neste estudo, e as sugestões consideradas pertinentes foram incorporadas ao material educativo. Com o auxílio de um painel de especialistas da área de farmacotécnica foi produzido um material educativo validado, contendo importantes informações para a escolha de excipientes de cápsulas preparadas magistralmente. O material educativo produzido pode representar um recurso importante para ser utilizado em atividades de formação continuada de profissionais que trabalham em farmácias de manipulação.
Palavras-chave: Excipientes. Cápsulas duras. Incompatibilidade. Classificação biofarmacêutica. Material educativo.
USO DE MEDICAMENTOS POTENCIALMENTE INAPROPRIADOS POR IDOSOS RESIDENTES EM UMA INSTITUIÇÃO DE LONGA PERMANÊNCIA EM GOIÁS, BRASIL
Authors: Da Silva Khalil Sara , Soares Rodrigues Maria Cristina , Kdudsi Khalil Omar Arafat 
Published: October 2021

Objetivo: Analisar o uso de medicamentos potencialmente inapropriados (MPIs) em prescrições para idosos em uma instituição de longa permanência, segundo os Critérios de Beers 2015. Método: Estudo transversal observacional de prontuários de 77 idosos residentes em uma instituição de longa permanência de Goiás, Brasil, sobre dados de saúde e medicamentos utilizados. A análise dos MPIs foi realizada por meio de análises descritivas. Resultados: Os medicamentos mais prevalentes como MPI-1 foram diazepam, omeprazol e risperidona, como MPI-2 diazepam, risperidona e citalopram e MPI-3, hidroclorotiazida e ácido acetilsalicílico. Conclusão: Prescrições de medicamentos para idosos devem ser centradas nas circunstâncias individuais e nos objetivos terapêuticos. Nesse sentido, esse estudo contribui para a prática da segurança do paciente idoso pelo uso de ferramenta explícita de análise de MPIs.
PROVA EM ALIMENTOS: A APLICAÇÃO DA TEORIA DA APARÊNCIA BASEADA EM PROVAS OBTIDAS ATRAVÉS DAS REDES SOCIAIS DIGITAIS
Authors: Wolney Póvoa Chagas Yasmim , Schelive Correia Italo 
Published: October 2021

A teoria da aparência baseia-se na cultura da digitalização vivida em nosso século, onde as pessoas se expõem cada vez mais na internet. Toda essa exposição traz consequências, e o direito vem abraçando essa autoprodução de provas no sentido de buscar se aproximar do princípio da verdade real. Analisa-se por meio deste estudo o juízo de ponderação das provas nas ações de fixação e majoração de alimentos, especificamente quando as alegações sobre a capacidade financeira declaradas pelo alimentante se mostram controversas a realidade exposta por este em suas redes sociais, devendo o juiz, nessa situação, encontrar mecanismos que o ajudem a elucidar a questão e trazer efetividade ao binômio necessidade e capacidade, atentando-se aos sinais exteriores de riqueza, conforme disposição da súmula 573 do Superior Tribunal de Justiça (STJ). A metodologia utilizada na pesquisa trata-se de uma análise bibliográfica de legislações, doutrinas, julgados dos tribunais pátrios e artigos científicos relacionados ao tema. A pesquisa resultou em esclarecimento acerca da aplicabilidade da teoria da aparência, demonstrando que diante da falta de comprovação da real situação econômica do alimentante quando da fixação dos alimentos, as provas extraídas de registros feitos pelo alimentante em suas redes sociais tornam-se perfeitamente cabíveis, permitindo que as sentenças sejam o mais equânime possível. Palavras-chave: Ação de alimentos; Redes sociais; Sinais exteriores de riqueza; Teoria da aparência.
ANÁLISE DE UM ÍNDICE DE CLASSIFICAÇÃO DA CONDIÇÃO DE PAVIMENTOS FLEXÍVEIS URBANOS
Authors: Silva Matheus , Salviatto Vitor Hugo , Da Silva Karen Amanda Barbosa , Da Silva Junior Carlos Alberto Prado , Fontenele Heliana Barbosa 
Published: October 2021

A ausência de recursos e medidas racionais para a conservação dos pavimentos nacionais apresenta-se cada vez maior. Assim, surge a necessidade do desenvolvimento de ferramentas simples e eficazes de monitoramento da condição do pavimento para auxiliar um Sistema de Gerência de Pavimentos Urbanos. Desse modo, esse trabalho teve como objetivo avaliar a aplicabilidade do Índice de Condição de Pavimentos Urbanos de João Pessoa na classificação da condição dos pavimentos urbanos. Para isso, a condição da malha viária de um campus universitário foi avaliada subjetivamente e pelo método do Pavement Condition Index. Na avaliação subjetiva foram utilizados dois painéis de avaliadores. Um deles recebeu apenas informações básicas do processo e o outro teve o apoio adicional de uma escala visual. As informações dos defeitos levantados foram utilizadas para encontrar os índices de condição das unidades amostrais avaliadas de acordo com as especificidades de cada um. Análises de correlação foram realizadas entre os índices obtidos em cada método de avaliação adotado. Dessa forma, os valores de coeficiente de correlação do índice de João Pessoa com as dos índices gerados nas avaliações subjetivas e objetiva variaram entre 0,54 a 0,61. Conclui-se que o índice avaliado está moderadamente correlacionado com os outros índices de condição do pavimento. Desse modo, infere-se que a aplicabilidade pode ter sido afetada por aspectos dos defeitos da região de análise que não são contemplados. Portanto, o índice deve ser ajustado para que possa representar a condição de pavimentos em regiões diferentes daquela em que foi desenvolvido.
Screening and Structure-Activity Relationship of Potential Compounds
against Proposed Targets of COVID-19 Infection
Authors: Ali Majid , Zaidi Asma , Farooq Umar , Bukhari Syed Majid 
Published: October 2021

Background:
With reference to COVID-19 pandemic prevailing across the globe, chloroquine
and hydroxychloroquine were reported as effective against the disease to some extent. This effectiveness
can be attributed to the glycosylation interruption of the Angiotensin-converting enzyme 2 (ACE2) receptor,
which is a known target for SARS-CoV-2 entery. On the other hand, studies suggest that the inhibition
of ACE2 can be lethal in certain cases, thereby causing cardiovascular disorders, especially in patients
already suffering from heart-related diseases.

Methods:
In this study, the most probable targets (other than ACE2) have been proposed for the treatment
of COVID-19 infection by taking chloroquine and hydroxychloroquine as reference drugs. SwissTargetPrediction
and PASSonline tools were used in order to achieve this objective. Known drugs against
each target possessing close relation to either viral infections or lung disorders were assessed from the
DrugBank database, and simultaneous efficacy of these drugs towards other proposed targets has been
analyzed. By taking the most effective drugs as a reference, similar compounds were screened from the
ChEMBL library by using the SwissSimilarity tool. Finally, molecular docking studies were performed
through MOE software by using screened compounds against proposed targets.

Results:
Four most probable targets have been proposed, which include chemokine receptors (CCRs),
dipeptidyl peptidase 4 (DPP4), muscarinic acetylcholine receptors (CHRMs), and histamine Nmethyltransferase
(HNMT). Furthermore, it has been evaluated that quinacrine and vildagliptin are effective
against most of the proposed targets. By taking vildagliptin as well as quinacrine as reference drugs,
further eight compounds with similar effectiveness against these targets have been screened from the
ChEMBL library. Molecular docking studies with CCR5, DPP4, and CHRM5 suggest that the quinacrine
and its analogue (ChEMBL1782742) as well as vildagliptin and its analogue (ChEMBL511785) are the
most suitable compounds as HITs for these targets.

Conclusions:
It has been established that the quinacrine, ChEMBL1782742, vildagliptin,
ChEMBL511785, mavorixafor, atropine, and N-(2-aminoethyl)-1-aziridineethanamine in descending
order can be considered as effective drugs for the treatment of COVID-19 infection.
Acetylcholinesterase Enzyme Inhibitor Molecules with Therapeutic Potential
for Alzheimer's Disease
Authors: Sivaraman Bhuvaneswari , Raji Vijaykumar , Velmurugan Bala Aakash , Natarajan Ramalakshmi 
Published: October 2021

:
Acetylcholinesterase (AchE), hydrolase enzyme, regulates the hydrolysis of acetylcholine
neurotransmitter in the neurons. AchE is found majorly in the central nervous system at the
site of cholinergic neurotransmission. It is involved in the pathophysiology of Alzheimer’s diseasecausing
dementia, cognitive impairment, behavioral and psychological symptoms. Recent findings
involved the inhibition of AchE that could aid in the treatment of Alzheimer's. Many drugs of different
classes are being analyzed in the clinical trials and examined for their potency. Drugs that
are used in the treatment of Alzheimer’s disease are donepezil, galantamine, tacrine, rivastigmine
showing major adverse effects. To overcome this, researchers work on novel drugs to elicit inhibition.
This review comprises many hybrids and non-hybrid forms of heteroaromatic and nonheteroaromatic
compounds that were designed and evaluated for AchE inhibition by Ellman’s
method of assay. These novel compounds may assist future perspectives in the discovery of novel
moieties against Alzheimer’s disease by the inhibition of AchE.