bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction of Compressive Strengths for Rice Husks Ash incorporated concrete, Using Neural Network and Reviews
Authors: Ngandu Cornelius Ngunjiri 
Published: March 2021

Modelling of concrete that incorporates agricultural wastes such as rice husk ash (RHA) could potentially enhance utilization of green concrete and application of sustainable construction materials. This paper evaluations compressive strength prediction for rice husk ash (RHA) cementitious material incorporated concrete using artificial neural networks (ANNs) one of the various prediction methods. The research is based on various previous experimental studies.Literature reviews of 72 datasets for RHA incorporated concrete from 15 previous researches, were used and subjected to ANNs models, having learning rate of 0.06 with tanh activation functions. Four(4) input variables were considered, namely:- superplasticizer or water reducers variation from control (%), water to binder ratio, percentage of RHA and control compressive strengths. Output variable was compressive strength of RHA cementitious material incorporated concrete. The ANN with 15 neurons in the hidden layer was selected and indicated overall values of 5.10MPa, 0.99, 3.81MPa and 9.73% for the root mean square error (RMSE), absolute factor of variance (R2), mean absolute error (MAE) and mean absolute percentage error (MAPE) respectively and for individual training, validation/checking and testing datasets, the RMSE, R2, MAE and MAPE ranging between 3.98MPa-6.56MPa, 0.98-0.99, 3.44MPa-4.94MPa and 9.19%-12.41% respectively. Generally, both predicted and original dataset, indicated higher and lower strength values for 5-10% and 15-30% RHA incorporated cementitious material concrete respectively compared to the control strengths.Considering that the study utilized data from different sources and with a wide range of concrete strengths the selected ANN showed relatively good performance. The study provides an indicator that machine learning techniques could accurately predict green concrete strength. Based on model performance the percentage RHA cementitious materials in concrete and the other 3 input variable had a significant impact on concrete strengths. Future research should be conducted to predict green concrete focused on particular concrete class.
Vom New Competition Tool zum Digital Markets Act: Die geplante EU-Regulierung für digitale Gatekeeper
Authors: Zimmer Daniel , Göhsl Jan-Frederick 
Published: March 2021

Zusammenfassung
Der im Dezember 2020 von der EU-Kommission vorgestellte Entwurf eines Digital Markets Act (kurz: DMA-E) enthält, anstelle des im Sommer 2020 noch angekündigten „New Competition Tool“, überwiegend Regelungen für digitale Gatekeeper und steht – für einige sicher überraschend – komplementär zum europäischen Wettbewerbsrecht. Die Kommission betritt sowohl mit der Anknüpfung an den bisher (im rechtstechnischen Sinne) unbekannten Begriff des Gatekeepers als auch mit der Einführung einer Ex-ante-Regulierung regelungstechnisch Neuland. Der vorliegende Beitrag nimmt eine erste grundsätzliche Einordnung des DMA-E vor und zeigt die wichtigsten Details der Regelungsinhalte auf. Die konkrete inhaltliche Ausgestaltung des DMA-E hängt eng mit der von der Kommission gewählten Rechtsgrundlage des DMA-E zusammen. Es wird gezeigt, dass der Erlass des vorgeschlagenen DMA zwar grundsätzlich ein Schritt in die richtige Richtung wäre, aber der noch bevorstehende Normgebungsprozess für Verbesserungen genutzt werden sollte. Außerdem wird untersucht, welche Elemente des ursprünglich geplanten „New Competition Tool“ ihren Weg in den DMA-E gefunden haben. Die Kommission könnte durch den DMA-E mittelbar sowohl im Hinblick auf die Fusionskontrolle als auch durch die Befugnis zum Erlass delegierter Rechtsakte eine nicht unerhebliche Erweiterung ihres Handlungsspielraums erfahren.
Nesting tree selection by scattered heronry birds of drought prone Northern Bankura, West Bengal, India: preference of Phoenix sylvestris near wetland-associated habitats
Authors: NAYAK Ananya 
Published: March 2021

The present study was conducted in the Gangajalghati block of Northern Bankura, India, to investigate the habitat and nest tree preference of three colonial waterbirds viz. Nycticorax nycticorax, Egretta garzetta, and Ardeola grayii. The study sites were surveyed for 20 months between 2017 and 2020. A total of 817 nests with an average of 204 per year were recorded on 13 tree species. Nycticorax nycticorax showed the maximum nest count followed by Egretta garzetta and Ardeola grayii. Relative abundance data revealed Phoenix sylvestris as the most abundant species (45%) of the area and harbours the highest proportion (33%) of nests. Pooled nest count data showed significantly higher (p < 0.01) total nest counts in the wetland associated habitats than others. The study observed more nest density of all three species near a cluster of small ponds than in a large water body. Year-wise difference in cumulative nest number and mean nest abundance of all three species was statistically insignificant. The interspecific nearest neighbour on Phoenix sylvestris were Egretta garzetta (88.37%) for Nycticorax nycticorax and Nycticorax nycticorax (83.25%) for Egretta garzetta and Ardeola grayii. Further, the study evaluated the impact of two tropical cyclones (Amphan and Fani) on the total nest count and found that more than 75% nests (p < 0.05) were destroyed by the mighty Amphan in May 2020. The study provides a baseline data on nesting trees and habitat preference of three species of heronry birds from Northern Bankura.
Microbial assessment and proximate composition of bread samples collected from different bakeries in Ogbomoso, Oyo state, Nigeria
Authors: OJO Segun S. , ADEOYE Adekunle O. , AJALA Adeladun S. , OLADIPO Iyabo C. 
Published: March 2021

Bread is a staple food in Nigeria and establishment of bakeries depend on the financial capacity and processing technique employed by processors. This has led to various breads in terms of nutrition and asepsis. In this study, three types of ready-to-eat bread were purchased from different bakery retail shops in Ogbomoso, Nigeria. The control sample was prepared in Food Science Department, Ladoke Akintola University of Technology Ogbomoso. These samples were analyzed for proximate composition, bacterial and fungal contamination using standard microbial procedure (SMP) and disc diffusion method (DDM) for sensitivity test to investigate safety handling practices during production, distribution and anti-microbial effect on microbial contaminant. The results of microbial analysis are as follows: total viable count (1.1 x103 - 4.5x103) cfu/g, coliform count (0-1.9x103) cfu/g, and mold count (0.3x 105 -3.7x105) cfu/g. The percentage of organisms isolated were E. coli. 15%, B. subtilis and S. aureus 20%, P. aureginosa 10%, S. cerevisiae 15.77%, R. stolonifer 13.46%, Mucor spp. and A. niger 18.08%, and P. notatum 7.69%. The result of the proximate analysis was as follows: protein (9.13- 9.79%), crude fat (1.64-4.50%), ash (1.32-1.77%), crude fibre (0.10-0.23%), moisture content (27.22 -29.05%) and carbohydrate (55.89-59.40%). The most sensitive antimicrobial agent was gentamycin across treatment. The organisms restricted septrin, augmenting, and chloramphenicol completely. Bacillus subtilis has the highest zone of inhibition with the use of gentamycin.
Case report of nasal pseudotumor – a rare presentation in severe haemophilia A with high titre inhibitors
Authors: Mandal Prakas Kumar , Garg Malini , Gantait Debasis , Jana Utpal 
Published: March 2021

Abstract
Haemophilia patients with inhibitors suffer from increased morbidity and mortality due to the ineffectiveness of factor VIII replacement. Pseudotumors are rare but dangerous complications in these patients, and nasal pseudotumors are even rarer. Here, we present the case of a young child with severe haemophilia A with high titre inhibitors who developed a nasal pseudotumor. When immune tolerance therapy was not possible due to financial constraints, he was treated with FEIBA prophylaxis and rituximab. The pseudotumor was managed with surgical excision. We conclude that epistaxis in haemophiliacs can be due to an underlying nasal pseudotumor, and highlight the use of rituximab for the eradication of inhibitors.
PLEVRAL HASTALIKLARIN TANISINDA VATS’IN ETKİNLİĞİ
Authors: TÜLÜCE Kerim , SEVİLGEN Gökçen 
Published: March 2021

Plevral hastalıklar klinikte karşımıza plevral kalınlaşma
ve plevral efüzyon olarak çıkmaktadır. Plevral
efüzyon, plevral boşlukta sıvı birikmesidir. Çalışmamızda,
plevral efüzyon veya plevral kalınlaşma nedeni
ile kliniğimize yatırdığımız ve Video Yardımlı Torakoskopik
Cerrahi (VATS) yaptığımız hastaların klinik
özelliklerini ve postoperatif patolojik sonuçlarını literatür
bilgileri eşliğinde paylaşmayı amaçladık.
Gereç ve Yöntem
2017 Ocak ile 2020 Ekim arasında plevral efüzyon
ve plevral kalınlaşma nedeniyle Recep Tayyip Erdoğan
Üniversitesi Eğitim Araştırma Hastanesi Göğüs
Cerrahisi Kliniği’ne yatırılan ve VATS uygulanan 58
hastanın dosyaları retrospektif olarak incelendi. Hastaların
yaş, cinsiyet, hastanede yatış süreleri belirlendi.
Plevral sıvıların biyokimyasal testleri, sitolojileri,
plevral biyopsi sonuçları ve hastanede yatış süreleri
kaydedildi. Plevral biyopsilerin patolojileri malign ve
benign olarak ayrılıp karşılaştırmalı olarak incelendi.
Bulgular
VATS ile biyopsi yapılan 58 hastanın 42’si (%72,4)
erkek, 16’sı (%27,6) kadındı. Ortalama yaş 58,4
±16,2 idi. Erkeklerin yaş ortalaması 58,2, kadınların
yaş ortalaması ise 61,2 idi. Hastanede yatış süresi
ortalama 4,1±1,4 gün idi. Hastaların 12’sinde (%20
,6) plevral efüzyona eşlik eden plevral kalınlaşma
mevcuttu. Plevral sıvı sitolojilerine bakıldığında 44
(%75,8) hastanın benign, 14 (%24,2) hastanın malign
sitoloji olduğu görüldü. Biyopsi sonucu 17 (%29,3)
hastada malign iken 41 (%70,7) hasta benign olarak
değerlendirildi. Malign olarak sonuçlanan hastaların
11’i (%64,7) adenokarsinom idi. Benign sonuçların ise
29’u (%70,7) kronik aktif inflamasyon olarak sonuçlandı.
Sonuç
Analizlerimizin sonucunda, VATS’ın plevral hastalıkların
tanı ve tedavisinde güvenle kullanılabilecek efektif
minimal invaziv bir yöntem olduğunu düşünüyoruz.
‘Don’t pee on that!’ Comparing environmental modification and medical management in cats with FIC
Authors: Poole Amelia 
Published: March 2021

PICO question
In cats with feline idiopathic cystitis (FIC) is environmental modification superior than medical management in preventing reoccurrence?

Clinical bottom line
Category of research question
Treatment
The number and type of study designs reviewed
16 papers were critically reviewed; 14 randomised trials and two case studies
Strength of evidence
Critical appraisal of the selected papers meeting the inclusion criteria collectively provide weak evidence in terms of their experimental design and implementation
Outcomes reported
There is weak evidence that any medication or environmental modification is successful in reducing the reoccurrence of FIC when compared to a placebo. Short-term use of amitriptyline can contribute to an increase in occurrence of FIC
Conclusion
In view of the strength of evidence and the outcomes from the studies the following conclusion is made; in cats with feline idiopathic cystitis there is weak evidence that environmental modification or medication are effective at preventing reoccurrence. Further research is required into the cause of FIC before comparisons on treatment options can be made, however, with the exception of short-term use of amitriptyline, environmental modification and systemic treatment of clinical signs did not contribute to an increase in occurrence of FIC

How to apply this evidence in practice
The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
Minimally invasive open reduction by a modified suture bridge with anchors for avulsion-type greater tuberosity fracture of the humerus
Authors: Kong Lingpeng , Yang Juanjuan , Yang Yongliang , Wang Fu 
Published: March 2021

Abstract
Background: This study aims to describe a modified surgical method of minimally invasive open reduction by a modified suture bridge with anchors for avulsion-type greater tuberosity fracture of the humerus and to evaluate its clinical effectiveness.Methods: From January 2015 to January 2018, 16 patients who were diagnosed with an avulsion-type greater tuberosity fracture of the proximal humerus and treated with minimally invasive open reduction by modified suture bridges with anchors were retrospectively studied. All patients were followed up with clinical examination and radiographs at 3 weeks, 6 weeks, 3 months, 6 months and 12 months after surgery and then every 6 months. Outcomes were assessed preoperatively and postoperatively with the visual analog scale (VAS), the University of California Los Angeles (UCLA) shoulders score, the American Shoulder and Elbow Surgeons score (ASES), and the range of motion (ROM) for shoulders.Results: There were 7 males and 9 females with an average age of 44.94 years. Six fractures involved the left shoulder, and 10 involved the right shoulder. The time between injury and operation ranged from 1 to 5 days, with an average of 2.32 days. The average length of stay was 6.5 ± 0.85 days; the mean operation time was 103.1 ± 7.23 minutes; and the mean amount of operative blood loss was 51.88 ± 6.40 ml. All patients achieved bone union within 3 months after surgery. The VAS score significantly decreased at 3 weeks postoperatively (p = 0.002), as did the average degree of forward elevation (p = 0.047). The mean degree of abduction increased at 6 weeks after the operation (p = 0.035), and the average degree of external rotation and internal rotation improved at 3 months postoperatively (p = 0.012; p = 0.007). The ASES score and the UCLA score improved at the 6-week follow-up (p = 0.092; p = 0.029). No procedure-related death or incision-related superficial or deep tissue infection was identified in any case. No iatrogenic neurovascular injuries or fractures were found in this study.Conclusion: The fracture block was fixed firmly by minimally invasive open reduction with a modified suture bridge with anchors. Patients were allowed to move their shoulder early after surgery and recovered quickly. It is an efficient method for the treatment of avulsion-type greater tuberosity fractures of the humerus.
LncRNA SUMO1P3 aggravates doxorubicin-induced cardiomyocyte apoptosis by targeting miR-93-5p / Bin1
Authors: Lin Xuefeng , Ma Aiqun 
Published: March 2021

Abstract
Background: Non-coding RNA plays a critical role in myocardial apoptosis induced by doxorubicin (DOX). However, the specific function of Long noncoding RNA (lncRNA) small ubiquitin-like modifier 1 pseudogene 3 (SUMO1P3) is unclear. The purpose of this study was to determine the role of lncRNA SUMO1P3 in myocardial apoptosis induced by DOX. Methods: QRT-PCR were used to detect the expression levels of SUMO1P3 and miR-93-5p in DOX-treated primary cardiomyocytes and rat models. QRT-PCR and Western blot were used to detect the expression levels of Bin1 in DOX-treated primary cardiomyocytes and rat models. The relationship between SUMO1P3, miR-93-5p and Bin1 was analyzed using bioinformatics analysis and Luciferase reporter assay. The effects of DOX on the viability and apoptosis of cardiomyocytes were evaluated by flow cytometry and CCK-8. The effects of SUMO1P3 on cardiomyocyte apoptosis were analyzed by TUNEL staining and echocardiography. Results: In DOX-treated primary cardiomyocytes and rat models, the expression levels of SUMO1P3 and Bin1 were significantly increased, while the expression levels of miR-93-5p were significantly reduced. MiR-93-5p was a direct target gene of SUMO1P3, and Bin1 was a direct target gene of miR-93-5p. In addition, miR-93-5p reversed the protective effect of SUMO1P3 knockout on cardiomyocytes by inhibiting the expression of Bin1. Conclusions: SUMO1P3 inhibited DOX-induced cardiomyocyte apoptosis through miR-93-5p/Bin1 axis.
Transfusion Practices In Advanced Cancer Patients
Authors: Marote Sara , Marinho Joana , Silva Maria Cândida , Gonçalves José António Ferraz 
Published: March 2021

Abstract
Purpose: Anemia is highly prevalent in patients with advanced cancer and adversely affects quality of life. There is limited data on the frequency, clinical utility and effectiveness of red blood cell transfusions (RBC), and no randomized controlled trials or clinical practice guidelines are available. The aim of this study was to evaluate clinician practices on RBC transfusion in an oncologic palliative care service (PCS) and its impact in patients’ symptoms, adverse events and overall survival.Methods: Retrospective analyses of all advanced cancer patients who received RBC transfusions admitted, during a 3-year period. Pre-blood counts, reason for transfusion, subjective benefit and objective outcomes were listed.Results: We identified 179 patients with a mean age of 67 years. A total of 435 RBC units, during 301 transfusion episodes were recorded. Asthenia/fatigue was the most frequent symptom (68%). The mean pretransfusion hemoglobin (Hb) was 6.85 g/dL and 48% patients had an Hb above 7 g/dL. Symptomatic benefit was achieved in 36% of patients. Adverse events were reported in 4%, with a 30-day survival rate of 57%. A statistically significant association between ECOG performance status (ECOG-PS) and symptomatic benefit was found (p=0.005). Hemoglobin level pre-transfusion, ECOG-PS and symptomatic benefit with transfusions were significantly associated with survival.Conclusion: This study suggests that advanced cancer patients with a higher level of functioning may have a bigger benefit from RBC transfusion. Post-transfusion symptomatic benefit, and pre-transfusion ECOG-PS and hemoglobin levels seem to be independent predictors of survival. Further studies are needed to develop validated measures of objective functional changes to evaluate the clinical impact of transfusions and to identify patients most likely to benefit from it.
What’s for Dinner? Assessing the Value of an Edible Invasive Species and Outreach Actions to Promote Its Consumption
Authors: Cerveira Inês , Baptista Vânia , Teodósio Maria Alexandra , Morais Pedro 
Published: March 2021

Abstract
Promoting the consumption of edible aquatic invasive species has gained popularity to minimize its impacts while easing pressure on native resources. Weakfish Cynoscion regalis (Bloch & Schneider, 1801) is one of the most recent invasive fish species in the Iberian Peninsula (Europe) which once sustained an important fishery in the native range (Northwest Atlantic Ocean). Portugal ranks third in the list of the world’s top fish consumers, so promoting a weakfish fishery could at least help minimize the impacts upon native species, since weakfish have innate traits that are likely appreciated by Portuguese fish consumers. However, introducing a new species to consumers is challenging owing to consumers’ habits and unfamiliarity with the species. So, we aimed to (i) evaluate the acceptance of weakfish by a panel of Portuguese fish consumers and (ii) create outreach actions – partnerships with local Chefs and press releases – to explain to a broader public what invasive species are and promote the consumption of edible aquatic invasive species. The survey that we conducted to Portuguese fish consumers showed that weakfish has great chances of being well accepted by the public – 90% of consumers would buy weakfish because they appreciated its appearance, flavour, and texture, besides being a wild fish. The outreach actions reached a few million people because 46 online articles were published, and three news pieces broadcasted on national television. Overall, our strategy greatly increased the public’s awareness about invasive species, which can be replicated elsewhere in the world.
Structure Identification of Fractional-order Complex-variable Network With Complex Coupling
Authors: Zhou Mingcong , Wu Zhaoyan 
Published: March 2021

Abstract
Fractional-order complex-variable dynamical network with complex coupling is considered in this paper. The topological structures and system parameters are assumed to be unknown. As we know, the topological structure and system parameters play a key role on the dynamical behavior of complex network. Thus, how to effectively identify them is a critical issue for better studying the network. Through designing proper controllers and updating laws, two corresponding network estimators are constructed. Based on the Lyapunov function method and Gronwall-Bellman integral inequality, the results are analytically derived. Finally, two numerical examples are performed to illustrate the feasibility of the theoretical results.
The Remanufacture of a Complex Part Using Hybrid Manufacturing (HM))
Authors: Barragan German Alberto , Ferreira Rodrigo Jose , Mariani Fabio , Silva Eraldo Jannone da , Coelho Reginaldo 
Published: March 2021

Abstract
The industrial importance of repair and remanufacturing processes has significantly increased over the past years, primarily due to their possible cost reductions and environmental benefits. Different techniques have been used for the development of such tasks in different areas, however, restrictions have been encountered in parts of high geometric complexity or those that require high mechanical performance. Additive Manufacturing (AM) technologies are an interesting alternative for remanufacturing, due to their advantageous mechanical properties and possible application in operations involving complex geometries. Hybrid Manufacturing (HM) technologies, which combine the advantages of AM processes with CNC machining in the same machine, have arisen as a new method that modernizes the repair and remanufacturing of metal components and offers a range of possible combinations of materials. This article addresses a remanufacturing operation that involves the use of an HM applied to an AISI 1045 component repaired with the addition of AISI 316L steel. The properties of the final parts showed the viability of the process for the remanufacturing of components of different materials and complex geometry. The parameters and strategy employed for the deposition of the additive material allowed us to obtain a piece without significant porosity, cracks, or defects. Microstructure and hardness in the sample were like those obtained in other published works. The manufacture or remanufacturing of components by the Directed Energy Deposition process employing stainless steel deposition on top of carbon steels opens a wide range of new applications. Those include the deposition and machining of complex 3D geometries