bluuebunny/crossref_metadata_2025_split huggingface dataset:
Newer Volatile Anesthetic Agents in Cardiac Anesthesia: Review of Literature
Authors: Mandke Alka , Sarkar Manjula , Deshpande Charulata , Maheshwari Arun , Kumar Bhupesh , Bhavani M. , Varma Shapna , Shah Hetal , Bhanu Laksmi , Khanderkar Shailesh , Ganpathy K. , Soni Kunal , Nebu Reena , Saxena Gaurav 
Published: March 2021

AbstractMyocardial protection with volatile anesthetic agents have been suggested by multiple studies. These studies, however, are scattered and are often limited to a particular aspect of cardiac anesthesia. Older inhalational agents like halothane is known to cause significant hepatic damage in patients undergoing long duration surgeries while isoflurane is known to have marked vasodilating properties that also affects the coronary arteries leading to coronary “steal” phenomenon. Additionally, newer agents, like sevoflurane and desflurane, have shown more prominent cardioprotective effects than older agents. We searched ScholarOne, Medline, Embase, and the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library. The medical subject headings (MeSH) terms “anaesthesia, inhalational,” “anaesthesia, intravenous, or TIVA,” and “Cardiac anaesthesia or Cardiac Surgery” were used. Additional studies were identified by review of the reference sections of all eligible studies. The aim of this review article is to bring together the evidences with newer inhalational agents and provide a holistic view of their benefits and shortcomings in cardiac anesthesia.
Simultaneous 3D surface profile and pressure measurement using phase-shift profilometry and pressure-sensitive paint
Authors: Li Yongzeng , Dong Zhe , Liang Lei , Liu Yingzheng , Peng Di 
Published: March 2021

A simultaneous three-dimensional (3D) surface profile and pressure measurement method that integrates phase-shift profilometry and pressure-sensitive paint (PSP2) is proposed. The advantages of this novel technique over previous 3D pressure-sensitive paint (3D-PSP) techniques include a simplified system with low cost, no interference with PSP coatings, high spatial resolution, and high accuracy. A modified digital light-processing (DLP) projector-structured light generator is used to encode ultraviolet light and generate fringe projection to excite the pressure-sensitive paint. The 3D profile is reconstructed using four phase-shifting emission images. Meanwhile, the surface intensity ratio distribution is obtained. The PSP2 method is applied to a nitrogen jet impingement experiment onto a spherical model. The intensity ratio results obtained using the PSP2 method differ little from the conventional PSP results obtained using uniform excitation. The phase distortion due to the emission intensity fluctuation leads to errors in surface profile measurement, and the fringe projection with high contrast improves surface profile measurement accuracy. In most of the final results, the average total errors between the reconstructed 3D surface and the CAD geometry are less than 0.1 mm.
First-principles molecular dynamics simulation study on Ti4+ ion in aqueous sulfuric acid
Authors: Choe Yoong-Kee , Tsuchida Eiji , Tokuda Kazuya , Otsuka Jun , Saito Yoshihiro , Masuno Atsunobu , Inoue Hiroyuki 
Published: March 2021

A first-principles molecular dynamics simulation study was carried out to investigate the structural features of Ti4+ in aqueous sulfuric acid. Ti4+ forms several stoichiometric compounds in aqueous sulfuric acid, the identity and structural information details of which have been the subject of numerous studies. Three stoichiometric compounds of Ti4+ in aqueous sulfuric acid were found in the simulations, namely, [Ti=O(OH)2(H2O)3], [Ti(OH)2(H2O)2SO4], and [Ti2O2(H2O)5(OH)2SO4]. The results indicated that HSO4− formed a complex with the Ti ion by releasing its proton, which implies that such a coordination increases the proton concentration in the solution. The multinuclear complex was formed in our simulation conditions (concentration: 1M Ti4+ and temperature: 353 K); the result supports the interpretation of a previous experimental study.
Performance demonstration of vacuum microwave components critical for the operation of the ITER low-field side reflectometer
Authors: Muscatello C. M. , Anderson J. P. , Boivin R. L. , Finkenthal D. K. , Gattuso A. , Kramer G. J. , LeSher M. , Mrazkova T. J. , Neilson G. H. , Peebles W. A. , Rhodes T. L. , Robinson J. T. , Torreblanca H. , Zeller K. , Zeng L. , Zolfaghari A. 
Published: March 2021

Final design studies in preparation for manufacturing have been performed for functional components of the vacuum portion of the ITER Low-Field Side Reflectometer (LFSR). These components consist of an antenna array, electron cyclotron heating (ECH) protection mirrors, phase calibration mirrors, and vacuum windows. Evaluation of these components was conducted at the LFSR test facility and DIII-D. The antenna array consists of six corrugated-waveguide antennas for simultaneous profile, fluctuation, and Doppler measurements. A diffraction grating, incorporated into the plasma-facing miter bend, provides protection of sensitive components from stray ECH at 170 GHz. For in situ phase calibration of the LFSR profile reflectometer, an embossed mirror is incorporated into the adjacent miter bend. Measurements of the radiated beam profile indicate that these components have a small, acceptable effect on mode conversion and beam quality. Baseline transmission characteristics of the dual-disk vacuum window are obtained and are used to guide ongoing developments. Preliminary simulations indicate that a surface-relief structure on the window surfaces can greatly improve transmission. The workability of real-time phase measurements was demonstrated on the DIII-D profile reflectometer. The new automated real-time analysis agrees well with the standard post-processing routine.
Photosynthesis tunes quantum-mechanical mixing of electronic and vibrational states to steer exciton energy transfer
Authors: Higgins Jacob S. , Lloyd Lawson T. , Sohail Sara H. , Allodi Marco A. , Otto John P. , Saer Rafael G. , Wood Ryan E. , Massey Sara C. , Ting Po-Chieh , Blankenship Robert E. , Engel Gregory S. 
Published: March 2021

Significance
Photosynthetic light-harvesting antennae transfer energy toward reaction centers with high efficiency, but in high light or oxidative environments, the antennae divert energy to protect the photosynthetic apparatus. For a decade, quantum effects driven by vibronic coupling, where electronic and vibrational states couple, have been suggested to explain the energy transfer efficiency, but questions remain whether quantum effects are merely consequences of molecular systems. Here, we show evidence that biology tunes interpigment vibronic coupling, indicating that the quantum mechanism is operative in the efficient transfer regime and exploited by evolution for photoprotection. Specifically, the Fenna–Matthews–Olson complex uses redox-active cysteine residues to tune the resonance between its excitons and a pigment vibration to steer excess excitation toward a quenching site.
A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike
Authors: Lu Mijia , Dravid Piyush , Zhang Yuexiu , Trivedi Sheetal , Li Anzhong , Harder Olivia , KC Mahesh , Chaiwatpongsakorn Supranee , Zani Ashley , Kenney Adam , Zeng Cong , Cai Chuanxi , Ye Chengjin , Liang Xueya , Shimamura Masako , Liu Shan-Lu , Mejias Asuncion , Ramilo Octavio , Boyaka Prosper N. , Qiu Jianming , Martinez-Sobrido Luis , Yount Jacob S. , Peeples Mark E. , Kapoor Amit , Niewiesk Stefan , Li Jianrong 
Published: March 2021

Significance
Measles virus (MeV) vaccine is one of the safest and most efficient vaccines with a track record in children. Here, we generated a panel of rMeV-based vaccines with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) S antigens inserted near 3′ of the MeV genome. The rMeV expressing a soluble stabilized, prefusion spike (preS) is much more potent in triggering SARS-CoV-2–specific neutralizing antibody than rMeV-based full-length S vaccine candidate. A single dose of rMeV-preS is sufficient to induce high levels of SARS-CoV-2 antibody in animals. Furthermore, rMeV-preS induces high levels of Th1-biased immunity. Hamsters immunized with rMeV-preS were completely protected against SARS-CoV-2 challenge. Our results demonstrate rMeV-preS is a safe and highly efficacious bivalent vaccine candidate for SARS-CoV-2 and MeV.
Self-pulsing of direct-current discharge in planar and curved geometries
Authors: Levko Dmitry , Raja Laxminarayan L 
Published: March 2021

Abstract
The self-pulsing of direct-current discharges in planar and curved geometries is studied using the two-dimensional axisymmetric fluid model. The simulation results show that in both cases the nature of self-oscillations is the same. They are obtained in the sub-normal mode of the discharge operation, for which the discharge has the negative differential resistance. We demonstrate that the negative differential resistance is due to both the non-linear and non-local dependence of the Townsend ionization coefficient on the electric field. We show that the self-oscillations are due to the ion transit time instability and are not related neither to RC resonance nor to the relation between the negative differential resistance and the ballast resistance as it is often suggested in the literature.
Therapeutic efficacy and cardioprotection of nucleolin-targeted doxorubicin-loaded ultrasound nanobubbles in treating triple-negative breast cancer
Authors: Fang Kejing , Wang Luofu , Huang Haiyun , Dong Shiwu , Guo Yanli 
Published: March 2021

Abstract
Targeted lipid nanobubbles as theranostic ultrasound molecular probes with both targeted contrast-enhanced ultrasound molecular imaging and synergistic treatment capabilities are expected to overcome severe challenges in the diagnosis and treatment of refractory triple-negative breast cancer (TNBC). In this study, AS1411 aptamer-functionalised nucleolin-targeted doxorubicin-loaded lipid nanobubbles (AS1411-DOX-NBs) were constructed, and their physicochemical properties as well as anti-tumour and cardioprotective efficacies were systematically tested and evaluated. The results showed that AS1411-DOX-NBs can carry and maintain the physicochemical and pharmacodynamic properties of doxorubicin (DOX) and show stronger tumour cell-killing ability in vitro by increasing the active uptake of drugs. AS1411-DOX-NBs also significantly inhibited the growth of TNBC xenografts while maintaining the weight and health of the mice. Echocardiography and pathological examination further confirmed that AS1411-DOX-NBs effectively caused tumour tissue apoptosis and necrosis while reducing DOX-induced cardiotoxicity. The AS1411-DOX-NBs constructed in this study enable both targeted contrast-enhanced ultrasound molecular imaging and synergistic therapeutic efficacy and can be used as safe and efficient theranostic ultrasound molecular probes for the diagnosis and treatment of TNBC.
Photocatalytic selective H2 release from formic acid enabled by CO2 captured carbon nitride
Authors: Wang Jinghui , Wang Xia , Qiu Lixin , Wang Honggang , Duan Limei , Kang Zhenhui , Liu Jinghai 
Published: March 2021

Abstract
The selective decomposition of formic acid (FA) traditionally needs to be carried out under high temperature with the noble metal-based catalysts. Meanwhile, it also encounters a separation of H2 and CO2 for pure H2 production. The photocatalytic FA dehydrogenation under mild conditions can meet a growing demand for sustainable H2 generation. Here, we reported a photocatalytic selective H2 release from FA decomposition at low temperature for pure H2 production by Pt/g-C3N4. Low-cost and easy-to-obtained urea was utilized to produce carbon nitride as the metal-free semiconductor photocatalyst, along with a photodeposition to obtain Pt/g-C3N4. The electrochemical evidences clearly demonstrate the photocatalytic activity of Pt/g-C3N4 to produce H2 and CO2 in one-step FA decomposition. And, the impedance is the lowest under simulated solar light of 70 mW cm−2 with a faster electron transfer kinetic. Under simulated solar light, H2 production rate is up to 1.59 mmol · h−1 · g−1 for FA with concentration at 2.65 mol l−1, 1700 000 times larger than that under visible light and 1928 times under ultraviolet (UV) light. DFT calculations further elucidate that nitrogen (N) active site at the g-C3N4 has an excellent adsorption towards CO2 molecule capture. Then, H2 molecules are selectively released to simultaneously separate H2 and CO2 in solution. Platinum (Pt) at Pt/g-C3N4 as the catalytic site contributes into the acceleration of H2 production.
Fabrication of nanostructured multi-unit vehicle for intestinal-specific delivery and controlled release of peptide
Authors: Feng Kun , Li Shu-Fang , Wei Yun-Shan , Zong Min-Hua , Hu Teng-Gen , Wu Hong , Han Shuang-Yan 
Published: March 2021

Abstract
An oral multi-unit delivery system was developed by incorporating the nanoparticle (NP) into the nanofiber mat and its efficiency for intestinal-specific delivery and controlled release of a peptide (insulin) was investigated. Initially, the influence of deacetylation degree (DD) of chitosan and ionic gelation methods on the properties of NPs was studied. High DD (95%) chitosan was attributed to higher encapsulation efficiency and stability when crosslinked with polyanion tripolyphosphate. Subsequently, the multi-unit system was fabricated using a pH-sensitive polymer (sodium alginate) as the coating layer to further encapsulate the NP. Fiber mat with an average diameter of 481 ± 47 nm could significantly decrease the burst release of insulin in acidic condition and release most amount of insulin (>60%) in the simulated intestinal medium. Furthermore, the encapsulated peptide remained in good integrity. This multi-unit carrier provides the better-designed vehicle for intestinal-specific delivery and controlled release of the peptide.
Radiation shielding properties of gadolinium-doped water
Authors: Ozturk Sertac 
Published: March 2021

Abstract
The utilization of water-filled radiation protection garments and walls has recently taken into consideration especially in space technologies, due to the fact that water is a material which is light, cheap, and easy-to-obtain. Furthermore, radiation shielding properties of water can be improved by adding soluble materials. In this study, a simulation-based study is presented to investigate the effects of the gadolinium additive in water for improvement on radiation shielding properties. GdCl
3 salt is selected as an additive substance. The obtained results using the Geant4 simulation toolkit indicate that the usage of gadolinium addition in water improves gamma-ray and neutron radiation properties significantly. While the linear attenuation coefficient values of water for gamma radiation increase about 60% with 20% of GdCl
3 addition, the increment of neutron macroscopic cross-section is about 40%.
Three-dimensional dual-wavelength optoacoustic angiography reveals arteriovenous anastomoses
Authors: Perekatova Valeriya , Nemirova Svetlana , Orlova Anna , Kirillin Mikhail , Kurnikov Alexey , Pavlova Ksenia , Khilov Aleksandr , Kovalchuk Andrey , Subochev Pavel 
Published: March 2021

Abstract
A dual-wavelength 532/1064 nm optoacoustic (OA) imaging system allows 3D visualizations of arteriovenous anastomoses (AVAs) with an acoustic spatial resolution (50 µm) at depths of up to 2 mm in vivo in rabbit ears. Both structural and spectral information from the OA data are employed to analyze the anatomical locations of the blood vessels and to distinguish between veins and arteries in the zone of their confluence. The OA monitoring of a rabbit ear under temperature-induced (43 °C/15 °C) shunting demonstrated the potential of the technique for the monitoring of functional arteriovenous anastomosis.
A Modulo-Based Computation for Kendall’s Phi Test for 2 by 2 Contingency Table
Authors: Chen Ray-Ming 
Published: March 2021

Abstract
Kendall’s Phi Test is very important technique in testing whether there exists a significant relation between variables under some known levels of experiments. However, the typical statistical testing would utilise some complex probability distribution for the statistic. In this article, we put forward a computational approach to effectively linearize Kendall’s Phi coefficients based on modulo operation. In our approach, the confidence levels would serve the threshold of the operation. Unlike typical approach which lists the whole distribution of the statistic, our method would concentrate only on the accumulated values needed. Such computation has merits in visualization and programming. In particular, if one is interested in Kendall’s Phi-based test, then this approach could largely reduce the complexity and computational time.
On the Properties of a Radially Symmetric Self-Similar Solution of a Nonlinear Heat Conduction Equation with a Source
Authors: Aripov M M , Mukimov A SH , Djabbarov O 
Published: March 2021

Abstract
In this work, new properties of a radially symmetric self-similar solution of the nonlinear heat equation with source were obtained. A self-similar solution was derived using the method of standard equations. These properties were proved by regulation the solution of the self-similar equation relative to the parameter of the nonlinear source by adding an additional parameter. The obtained properties were verified by numerical experiments.
Higher Education 4.0 Technologies: Survey of Immersive, Interactive Content Development and Materials Deployment Within A Developing Nation
Authors: Adnan A H M , Karim R A , Shah D S M , Tahir M H M , Shak M S Ya 
Published: March 2021

Abstract
Industry 4.0 manufacturing processes are making advanced hardware and the latest software cheaper, and easier to employ for teaching and learning. In the process, the objectives of the Higher Education 4.0 initiative are being realized. Tertiary educators should take heed of these developments so that their undergraduate students could benefit from education technologies that are geared for the current technologically savvy generation. The question that needs to be asked is, are tertiary educators taking advantage of innovative teaching and learning technologies by becoming content developers? And, are they deploying educational materials that align to the principles of Higher Education 4.0 for the advantage of their tertiary students? This empirical paper reports and discusses findings from a survey on content development and materials deployment by Malaysian tertiary educators from different fields across a range of tertiary institutions in Peninsula Malaysia. Results do not look encouraging. Some respondents stated that they do use high-end learning materials in teaching and learning, just not content that they have created on their own. Only a minority are taking advantage of new technological tools to create their proprietary immersive and interactive materials, a finding that might be the case for many developing nations across the globe.
Industry 4.0 critical skills and career readiness of ASEAN TVET tertiary students in Malaysia, Indonesia and Brunei
Authors: Adnan A H M , Rahmat A M , Mohtar N M , Anuar N 
Published: March 2021

Abstract
Industry 4.0 is a time of serious disruptions whereby monumental changes are happening in the world of work, in the ways we teach and learn, and in the ways that we live our lives. Increased automation coupled with artificial intelligence are making humans obsolete, for instance, in the manufacturing and service industries. Intelligent machines are useful but human beings are losing livelihoods or becoming trapped in the ‘gig economy’. This empirical study collected and examined qualitative data related to Industry 4.0 critical skills outlined by the World Economic Forum from ASEAN student leaders at five tertiary polytechnics in Brunei, Indonesia and Malaysia. ‘Netnography’ data collection instruments were employed namely online interviews and group discussions within a cloud-based instant messaging and VOIP service together with face-to-face focus group discussions, where permissible. Results do not look too promising with a number of the participants still in the dark about what skills they need to acquire for Industry 4.0 and how they must hone those skills before they enter an uncertain world of work in 2020 and beyond. Clearly, ASEAN nations must move fast, un-train and retrain tertiary students in the vital skills needed to survive and succeed in the post-Industry 4.0 era.
Continuance intention to use e-campus: The role of service quality in Malaysian higher education context
Authors: Rani Mohd Jaffri bin Abdul , Razak Fahmi Zaidi Abdul 
Published: March 2021

Abstract
This article examines the role of service quality on continuance intention to use e-campus among private higher education students. This research uses only one predictor taken out from well-established information system success model, namely, ‘De Lone & Mclean Success Model. A quantitative research method is used and paper-and-pencil self-administered questionnaire survey as method of data collection. Data was analysed using simple linear regression analysis. The results indicate that service quality were positively related to continuance intention to use e-campus explaining a total of 24.2% variance. This paper provides an extension of service quality in the post adoption stage at private higher learning context. Implications for service provider are highlighted.
E-campus usage: A descriptive study on Malaysian setting
Authors: Mokhtar Anis Azzyaty bte , Razak Fahmi Zaidi Abdul 
Published: March 2021

Abstract
This study examines the demographic information of student e-learning usage in Malaysian private higher learning institution. Four demographic factor were involved in this study namely gender, race, age and faculty. Data were collected from 500 undergraduate and postgraduate students from private university in Kuantan Malaysia using a validated set of questionnaire. The data were collected by means of a paper-and-pencil self-administered questionnaire and analyzed by using simple linear regression analysis. The findings found that differs on the basis of gender, race, age and faculty.
Exploring the relationship between system quality and continuance intention to use e-campus: The mediating effect of satisfaction
Authors: Razak Fahmi Zaidi Abdul , Mokhtar Ahmad Effat , Rahman Asmadi Abdul , Abidin Mohd Zawavi Zainal 
Published: March 2021

Abstract
The rapid growth of information technology has led many sectors to equip their organizations with the latest IT facilities. Although many organizations are equipped with IT facilities, there are some institutions that do not fully utilize IT facilities. This study will identify the role of satisfaction as mediator of the relationship between system quality and continuance intention. The study was conducted at a private university in the east coast of Malaysia. The research data in the analysis uses Bootstrapping techniques to test the hypothesis. Research findings indicate that satisfaction plays a significant role as a mediator. Further studies discuss practical implications.
Factors influencing e-campus satisfaction: A content quality perspective
Authors: Razak Fahmi Zaidi Abdul , Rahman Asmadi Abdul , Moktar Ahmad Effat 
Published: March 2021

Abstract
The purpose of this study is to investigate the relationship between content quality and user satisfaction to use e-campus. To achieve this objective, we use data from 315 e-campus users from Malaysian private higher learning institution through paper-and-pencil self-administered questionnaire survey. We use validated questionnaire derived from the literature. Our results show that content quality directly influences e-campus user satisfaction explaining a total of 33% variance. Implications from this finding are further elaborated.