bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impacts of Low-cost Robotic Pets for Older Adults and People With Dementia: Scoping Review
Authors: Koh Wei Qi , Ang Faith Xin Hui , Casey Dympna 
Published: January 2021

Background
Older adults and people with dementia are particularly vulnerable to social isolation. Social robots, including robotic pets, are promising technological interventions that can benefit the psychosocial health of older adults and people with dementia. However, issues such as high costs can lead to a lack of equal access and concerns about infection control. Although there are previous reviews on the use of robotic pets for older adults and people with dementia, none have included or had a focus on low-cost and familiarly and realistically designed pet robots.

Objective
The aim of this review is to synthesize evidence on the delivery and impact of low-cost, familiarly and realistically designed interactive robotic pets for older adults and people with dementia.

Methods
The Arksey and O’Malley framework was used to guide this review. First, the research question was identified. Second, searches were conducted on five electronic databases and Google Scholar. Studies were selected using a two-phase screening process, where two reviewers independently screened and extracted data using a standardized data extraction form. Finally, the results were discussed, categorized, and presented narratively.

Results
A total of 9 studies were included in the review. Positive impacts related to several psychosocial domains, including mood and affect, communication and social interaction, companionship, and other well-being outcomes. Issues and concerns associated with its use included misperceptions of the robotic pets as a live animal, ethical issues of attachment, negative reactions by users, and other pragmatic concerns such as hygiene and cost.

Conclusions
Overall, the findings resonate with previous studies that investigated the effectiveness of other social robots, demonstrating the promise of these low-cost robotic pets in addressing the psychosocial needs of older adults and people with dementia. The affordability of these robotic pets appeared to influence the practicalities of real-world use, such as intervention delivery and infection control, which are especially relevant in light of COVID-19. Moving forward, studies should also consider comparing the effects of these low-cost robots with other robotic pets.
FACTORS ASSOCIATED WITH BODY MASS INDEX IN CHILDREN – A COMMUNITY-BASED STUDY
Authors: PALADUGU NIKHILA , RAYITI RAMAKRISHNA , NUTAKKI SIDDHARTHA , GADDE RAJASREE , K SAILAJA , GHANTA VIJAYA KUMAR , SRUJANI KANAGALA VISWA 
Published: January 2021

Objectives: The increasing prevalence of overweight, obesity, and underweight in children has implications for their future health and it is vital to understand the modifiable factors that contribute to it. The study’s main objective is to determine the factors associated with the body mass index in children.
Methods: A cross-sectional study was conducted among 346 school children over a period of 6 months. Data were collected using self-administered questionnaire. Physical measurements such as height and weight were obtained from parents. Body mass index was calculated using kg/m2. Children were categorized as overweight, obese, normal, and underweight using their body mass index scores and the factors associated with BMI in children were estimated.
Results: The prevalence of overweight, obesity, normal, and underweight among children was 10.40%, 17.92%, 24.28%, and 41.67%, respectively. Intake of fast food, sweetened beverages, junk food, and consumption of food while watching television, media time indicated a significant relationship with body mass index.
Conclusion: Health care professionals should educate parents and children regarding healthy nutrition and regular physical activity. The implications of obesity, overweight, and underweight should be well explained to make desirable lifestyle modifications for a better future.
Aspek Legalitas Penyimpanan Minuta Akta Notaris Secara Elektronik
Authors: Nisa' Naily Zahrotun 
Published: January 2021

Penelitian ini bertujuan untuk (1) menjelaskan makna keautentikan dari segi hukum perdata Belanda dan Indonesia, (2) menjelaskan aspek legalitas serta mekanisme penyimpanan minuta akta secara elektronik di Indonesia, (3) menjelaskan kekuatan pembuktian minuta akta elektronik di muka pengadilan. Metode penelitian yang digunakan adalah yuridis normatif dengan cara menelaah teori, konsep hukum serta peraturan perundang-undangan yang berkaitan dengan penelitian ini. Hasil penelitian menunjukkan bahwa minuta akta notaris yang disimpan secara elektronik dapat terjaga keautentikan dan keamanannya. Solusinya dengan adanya harmonisasi antara regulasi dan teknologi yang didukung adanya sistem identifikasi dan autentikasi yang akuntabel. hal tersebut dapat merujuk pada penyelenggaraan keautentikan dokumen di Belanda dengan harmonisasi ketentuan regional uni eropa berupa peraturan nomor 910 tahun 2014 tentang e-identification and trust services.
Penerapan Media Game Ular Tangga Digital untuk Meningkatkan Hasil Belajar Tematik
Authors: Novita Lina , Sundari Fitri Siti , Rabani Khansa Rohadatul’Aisy 
Published: January 2021

Kurikulum 2013 lebih menekankan keaktifan peserta didik, namun penerapan pembelajaran masih berpusat pada guru. Salah satu penyebab adalah kurangnya penggunaan media pembelajaran. Oleh sebab itu perlu dilakukan upaya dalam meningkatkan kualitas pembelajaran. Penelitian ini bertujuan untuk meningkatkan hasil belajar dan menumbuhkan keaktifan siswa dengan penggunaan media ular tangga digital. Metode penelitian tindakan kelas digunakan dalam penelitian ini. Subjek penelitian siswa kelas IV berjumlah 35 siswa. Penelitian ini dilakukan dengan 2 siklus, yang terdiri dari perencanaan, pelaksanaan, pengamatan, dan refleksi. Siklus 2 dilakukan, apabila pada siklus 1 belum mencapai indikator keberhasilan pembelajaran. Pengumpulan data dan analisis data dilakukan dari hasil pelaksanaan pembelajaran dan observasi yang dilakukan kolaborator. Hasil penelitian menunjukkan adanya peningkatan hasil belajar dan perubahan sikap dengan penggunaan media game ular tangga digital. Peningkatan tersebut dibuktikan dengan angka rata-rata siklus 1, yaitu 74,42 meningkat menjadi 84,02 pada siklus 2, artinya terjadi peningkatan 9,6. Dengan demikian dapat disimpulkan bahwa media ular tangga digital dapat meningkatkan hasil belajar dan adanya perubahan aktivitas siswa pada proses pembelajaran. Hal ini dapat dikatakan bahwa pembelajaran dengan menggunakan media baik itu ular tangga digital maupun media pembelajaran lainnya dapat mengubah pembelajaran menjadi lebih aktif
How well do integrated 3D models predict alveolar defects after treatment with clear aligners?
Authors: Jiang Ting , Wang Jian Kai , Jiang Yang Yang , Hu Zheng , Tang Guo Hua 
Published: January 2021

ABSTRACT

Objectives
To evaluate the accuracy of integrated models (IMs) constructed by pretreatment cone-beam computed tomography (pre-CBCT) in diagnosing alveolar defects after treatment with clear aligners.

Materials and Methods
Pre-CBCT and posttreatment cone-beam computed tomography (CBCT) scans from 69 patients who completed nonextraction treatment with clear aligners were collected. The IMs comprised anterior teeth in predicted positions and alveolar bone from pre-CBCT scans. The accuracy of the IMs for identifying dehiscences or fenestrations was evaluated by comparing the means of the defect volumes, absolute mean differences, and Pearson correlation coefficients with those measured from post-CBCT scans. Defect prediction accuracy was assessed by sensitivity, specificity, positive predictive values, and negative predictive values. Factors possibly affecting changes in mandibular alveolar defects were analyzed using a mixed linear model.

Results
The IM measurements showed mean deviations of 2.82 ± 9.99 mm3 for fenestrations and 3.67 ± 9.93 mm3 for dehiscences. The absolute mean differences were 4.50 ± 9.35 mm3 for fenestrations and 5.17 ± 9.24 mm3 for dehiscences. The specificities of the IMs were higher than 0.8, whereas the sensitivities were both lower (fenestration = 0.41; dehiscence = 0.53). The positive predictive values were unacceptable (fenestration = 0.52; dehiscence = 0.62), and the overall reliability was low (&lt;0.80). Molar distalization and proclination were positively correlated with significant increases in alveolar defects at the mandibular incisors after treatment.

Conclusions
Alveolar defects after clear aligner treatment cannot be simulated accurately by IMs constructed from pre-CBCT. Caution should be taken in the treatment of crowding with proclination and molar distalization for the safety of alveolar bone at the mandibular incisors.
Does the rhythm and appliance type of rapid maxillary expansion have an effect on root resorption?
Authors: Malkoç Sıddık , Alçin Rukiye , Uzel Aslıhan 
Published: January 2021

ABSTRACT

Objectives
To evaluate the volume, amount, and localization of root resorption in the upper first premolars by micro–computed tomography (micro-CT) after three different rapid maxillary expansion appliances and two different activation rhythms.

Materials and Methods
The patients were divided into three groups; Hyrax, acrylic cap splint (ACS), and full coverage acrylic bonded (FCAB) appliances. Each group was then divided into the following two subgroups: rapid maxillary expansion (RME) and semirapid maxillary expansion (SRME). After expansion was completed, the appliances were stabilized for 12 weeks during the retention period. For each group, 10 premolars (for a total of 60 premolars) were scanned with the micro-CT (SkyScan). The reconstructed 3D images of each root sample were divided into six regions. The resorption craters on these six different root surfaces were analyzed by special CTAn (SkyScan) software for direct volumetric measurements. Kruskal-Wallis one-way analysis of variance and Mann-Whitney U tests were used for statistical analysis.

Results
The total volume of root resorption was less with FCAB than with ACS and Hyrax (P &lt; .001). In all groups, a greater volume of resorption was found on the buccal surface than on the lingual surface (P &lt; .001). No significant differences were found between the RME and SRME groups (P &gt; .05).

Conclusions
All expansion appliances caused root resorption in the upper first premolar teeth, but FCAB may be safer in terms of root resorption. The resorption craters were generally concentrated on the buccal surface. There was no effect of activation rhythm on root resorption.
Analisis Faktor-faktor yang Mempengaruhi Perilaku Penggunaan Sistem E-Learning Undiksha dengan Model Unified Theory of Acceptance and Use of Technology (UTAUT)
Authors: Sukarya I Gede Arya , Pradnyana I Made Ardwi , Sugihartini Nyoman 
Published: January 2021

Sistem E-learning dikembangkan oleh Undiksha untuk meningkatkan efektivitas dan kualitas pembelajaran. Namun pada kenyataannya E-learning Undiksha belum dimanfaatkan secara maksimal oleh dosen di lingkungan Undiksha. Pengguna dapat menerima dan menggunakan sistem adalah hal yang penting untuk dapat mengetahui tingkat keberhasilan dari implementasi sistem tersebut. Oleh karena itu penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi perilaku penggunaan sistem E-learning Undiksha dengan model Unified Theory of Acceptance and Use of Technology (UTAUT). UTAUT merupakan salah satu model penerimaan teknologi yang menggabungkan delapan teori penerimaan teknologi sebelumnya. UTAUT memiliki empat konstruk utama yaitu ekspektasi kinerja, ekspektasi usaha, pengaruh sosial dan kondisi yang memfasilitasi. Data diperoleh dengan cara menyebarkan kuesioner tertutup dengan sampel 64 Dosen Undiksha. Dianalisis menggunakan software SPSS. Hasil penelitian ini menunjukkan bahwa (1) Ekspektasi kinerja, ekpektasi usaha, pengaruh sosial dan kondisi yang memfasiitasi berpengaruh positif terhadap perilaku penggunaan sistem E-learning Undiksha (2) Variabel moderator jenis kelamin memperkuat hubungan ekspektasi kinerja dan ekspektasi usaha terhadap perilaku penggunaan sistem E-learning Undiksha sedangkan untuk variabel moderator jenis kelamin memperlemah hubungan variabel pengaruh sosial terhadap perilaku penggunaan sistem E-learning Undiksha (3) Variabel moderator umur memperkuat hubungan variabel ekspektasi kinerja, ekspektasi usaha, pengaruh sosial dan kondisi yang memfasilitasi terhadap perilaku penggunaan sistem E-learning Undiksha (4) Variabel moderator pengalaman memperkuat hubungan ekspektasi usaha, pengaruh sosial dan kondisi yang memfasilitasi terhadap perilaku penggunaan sistem E-learning Undiksha.
Sistem Seleksi Penerimaan Siswa Baru Menggunakan Metode Weighted Product
Authors: Mayhendra Bella , Sokibi Petrus 
Published: January 2021

The Acceptance of new students in SMA Negeri 1 Rajagaluh is done by choosing alternate prospective students who qualify based on predetermined variables. The problem faced by the team of selectors is how to determine the best students from a number of prospective students who have advantages and disadvantages of each with a very fast time so often mistakes in the selection of new students in SMA Negeri 1 Rajagaluh and less objective in providing an assessment for selected. In this thesis built a new decision support selection system using the method of Weighted Product (WP). The variables used in the selection of admissions in SMA Negeri 1 Rajagaluh are the national final examination scores, the final examination score of the school, the value of junior high school report cards. This system is designed using PHP programming language (Hypertext Processor File) as well as MySQL database as a database server. This system generates rankings of prospective new students in accordance with the procedure of admission of students in SMA Negeri 1 Rajagaluh, where the result is in the form of student ranking. This system has several advantages that variable and a weight value of variables used in this system is dynamic. This system also has a shortage of the range of values on the variable is still static
Factors influencing complications following mastectomy procedures in dogs with mammary gland tumors: 140 cases (2009–2015)
Authors: Evans Brolin J. , Holt David E. , Stefanovski Darko , Sorenmo Karin U. 
Published: January 2021

Abstract

OBJECTIVE
To evaluate complication rates for various types of mastectomy procedures, identify factors associated with an increased risk of complications, and determine the consequences of such complications.

ANIMALS
140 female dogs that underwent 154 separate mastectomy procedures to treat mammary gland tumors.

PROCEDURES
Medical records of dogs in the Penn Vet Shelter Canine Mammary Tumor Program from July 2009 to March 2015 were reviewed. Data regarding signalment, tumor characteristics (ie, number and size, benign or malignant, and bilateral or unilateral), mastectomy type, anesthesia time, concurrent ovariohysterectomy or ovariectomy, surgeons’ qualifications, antimicrobial administration after surgery, postoperative placement of surgical drains, and complications (seroma, abscess, dehiscence, or infection) were collected. Complications that required hospitalization were recorded. Fisher exact tests were used to evaluate associations between variables of interest and complications. Multivariable analysis was used to identify factors independently associated with an increased risk of complications.

RESULTS
Complication rate following all mastectomy procedures was 16.9% (26/154); of these, 9 (34.6%) required hospitalization. High body weight, undergoing bilateral mastectomy, and postoperative antimicrobial administration were associated with significantly increased odds of complications. The odds of complications associated with postoperative antimicrobial administration, however, varied according to mastectomy type; dogs undergoing chain mastectomy that did not receive antimicrobials postoperatively had the highest odds of developing complications. Dogs undergoing concurrent ovariohysterectomy or ovariectomy had significantly decreased odds of complications.

CONCLUSIONS AND CLINICAL RELEVANCE
Previously spayed dogs with a large body size that underwent the most extensive mastectomy procedures had increased odds of having postoperative complications.
Reporting quality of abstracts of veterinary randomized controlled trials
Authors: Maranville Rachel E. , Popken Andrea K. , Reynders Reint Meursinge , Brandão João , Di Girolamo Nicola 
Published: January 2021

Abstract

OBJECTIVE
To evaluate the adherence of veterinary randomized controlled trial (RCT) abstracts to the recommendations on minimum abstract information included in the Consolidated Standards of Reporting Trials (CONSORT) checklist for RCT abstracts and to identify characteristics associated with the number of CONSORT items reported.

SAMPLE
212 abstracts representing all RCTs published in 5 general veterinary journals in 2013 and 2018.

PROCEDURES
2 investigators independently assessed whether each of the 15 CONSORT checklist items for abstracts applicable to veterinary medicine was reported. Generalized linear mixed models were built to explore associations of selected variables with the total number of checklist items reported.

RESULTS
Abstracts included a median of 5 checklist items (range, 2 to 10 items). None met the recommendations for reporting participant recruitment and funding source. Less than 25% of abstracts met the recommendations for the title, participant eligibility criteria, primary outcome, randomization technique, blinding, numbers analyzed, primary outcome results, and harms to participants. The number of items reported was higher in abstracts of RCTs that included clinical patients (vs other participants; OR, 1.13; 95% CI, 1.05 to 1.22). The number of items reported did not significantly change over time.

CONCLUSIONS AND CLINICAL RELEVANCE
Results suggested that the reporting quality of abstracts of RCTs in general veterinary journals was suboptimal per CONSORT recommendations. Because abstracts may be the only reference material available in certain settings, improvements are warranted to ensure readers have the information they need to properly interpret reported findings.
Antibacterial and antitumor activity of the species Prunella vulgaris L.
Authors: Groşan Alexandra , Vari Camil-Eugen , Ştefănescu Ruxandra , Danciu Corina , Pavel Ioana Zinuca , Dehelean Cristina , Man Adrian , David Remona Eliza , Vlase Laurian , Muntean Lucia Daniela 
Published: January 2021

Abstract

Background: Prunella vulgaris L., known as self-healing herb, is a widely spread species in the spontaneous flora with beneficial effects on human health, a fact proven in particular by Asian researchers. The aim of this study was to evaluate the antitumor activity and the antibacterial effect on different bacterial strains, including multidrug-resistant ones, depending on the type of solvent used (aqueous, hydroalcoholic), the plant product taken into consideration (spike inflorescence, leaf), its quantity and the concentration of active principles.

Material and method: For screening of antimicrobial susceptibility, both minimum inhibitory concentration and minimum bactericidal concentration were determined on Escherichia coli, Klebsiella pneumoniae, Providencia stuartii, Pseudomonas aeruginosai, and methicillin-resistant Staphylococcus aureus species, including reference strains and hospital strains. Leaves and flower extracts (aqueous and 70% methanolic) were first assessed, and the one with the best antibacterial potential was further tested as a concentrated extract. The antitumor activity was determined on MDA-MB-231 breast adenocarcinoma cells and on a non-tumor cell line, MCF-10A breast epithelial cells by means of Alamar blue technique and Scratch assay.

Results: Inflorescence extracts showed better bacteriostatic effects than leaf extracts on most bacteria, in both aqueous and hydroalcoholic extracts. The concentrated extract of spike inflorescence showed measurable activity with good effects on Gram-positive bacteria, but also on multidrug-resistant Gram-negative ones. The 70% methanolic extract of the species Prunella vulgaris L. (spike inflorescence) demonstrated a concentration-dependent cytotoxic and anti-migratory activity on MDA-MB-231 breast cancer cells, while affecting the non-tumor cell line less.

Conclusions: The results suggest that Prunella vulgaris extracts present antibacterial potential in the complementary treatment of multidrug-resistant infections. The extract from the spike inflorescence of Prunella vulgaris L. produced a dose and time-dependent reduction in cell viability and migration, eliciting a stronger effect on the breast adenocarcinoma cell line.
The potential of programmed death ligand-1 expression in ovarian malignant germ cell tumors as a prognostic factor
Authors: Harahap Fadhlina , Tjahjadi Hartono , Kusmardi Kusmardi 
Published: January 2021

Abstract

Background: Ovarian malignant germ cell tumors (OMGCT) that fail to recover with conventional management have a poor prognosis. Several recurrent events after chemotherapy have been found. Programmed death ligand-1 (PD-L1) is expressed in various malignancies and tumor infiltrating lymphocytes (TILs) with a known role as a prognostic factor.

Objective: To determine the role of PD-L1 expression in OMGCT in determining overall survival (OS) and progression-free survival (PFS).

Methods: Expression of PD-L1 was assessed from PD-L1 immunohisto-chemistry in paraffin block preparations from 40 patients diagnosed with OMGCT who met the inclusion criteria. The relationship between clinicopathological characteristics and OS and PFS was analyzed using the Kaplan-Meier method and multivariate analysis using the Cox regression model.

Results: No significant relationship was found between PD-L1 expression in tumor cells with 2-year OS (p=0.275) and PFS (p=0.421) in OMGCT. A significant association was found between histopathologic types with 2-year OS (p=0.002), and cancer stage with 2- year OS (p=0.028) and PFS (p=0.014).

Conclusion: PD-L1 expression in tumor cells was not related to OS and PFS in OMGCT patients. There is a tendency for death and recurrence in patients OMGCTs with low PD-L1 expression in tumor cells.
The Diagnostic Value of Monocyte Chemoattractant Protein-1, Compared with Procalcitonin, C-reactive Protein, and Lactate in Bacteremia Estimation for Patients with Febrile Neutropenia
Authors: Ödemiş İlker , Köse Şükran , Senger Süheyla Serin , Akbulut İlkay , Çelik Didem 
Published: January 2021

Abstract
Bacteremia in the febrile neutropenic patients significantly increases the mortality. It takes a long time to complete the blood culture for the diagnosis of bacteremia. Therefore, quick and specific markers are needed for the prediction of bacteremia. The purpose of this study are to compare the diagnostic value of lactate, procalcitonin, C-reactive protein (CRP) and monocyte chemoattractant protein-1 (MCP-1) levels in a patient with febrile neutropenia, and to evaluate its usefulness in predicting bacteremia. This study was designed to be prospective case-control study. Forty-eight patients and forty control cases aged 18 years or older who were monitored between May 2016 and May 2017 were included in the study. P-value as <0.05 was accepted to be significant. Significantly increased values were determined by the level of inflammatory markers of patients compared to the control group. The highest diagnostic odds ratio were found to be in MCP-1. For patients with febrile neutropenia, CRP (83.3%), and MCP-1 (81.2%) were the most sensitive markers while lactate (85.0%), MCP-1 (75%), and procalcitonin (75%) were the most specific markers. CRP was the only beneficial biomarker in the estimation of bacteremia. No significant results were observed for any biomarker for the prediction of the gram positive/negative discrimination of bacteria in the blood culture. We believe that CRP, MCP-1, and lactate levels can be taken into consideration for diagnosis, and CRP can be beneficial in the estimation of bacteremia.