bluuebunny/crossref_metadata_2025_split huggingface dataset:
Symmetry analysis and equivalence transformations for the construction and reduction of constitutive models
Authors: Ganghoffer J. F. , Rahouadj R. , Cheviakov A. 
Published: January 2021

AbstractA methodology based on Lie analysis is proposed to investigate the mechanical behavior of materials exhibiting experimental master curves. It is based on the idea that the mechanical response of materials is associated with hidden symmetries reflected in the form of the energy functional and the dissipation potential leading to constitutive laws written in the framework of the thermodynamics of irreversible processes. In constitutive modeling, symmetry analysis lets one formulate the response of a material in terms of so-called master curves, and construct rheological models based on a limited number of measurements. The application of symmetry methods leads to model reduction in a double sense: in treating large amounts number of measurements data to reduce them in a form exploitable for the construction of constitutive models, and by exploiting equivalence transformations extending point symmetries to efficiently reduce the number of significant parameters, and thus the computational cost of solving boundary value problems (BVPs). The symmetry framework and related conservation law analysis provide invariance properties of the constitutive models, allowing to predict the influence of a variation of the model parameters on the material response or on the solution of BVPs posed over spatial domains. The first part of the paper is devoted to the presentation of the general methodology proposed in this contribution. Examples of construction of rheological models based on experimental data are given for setting up a reduced model of the uniaxial creep and rupture behaviour of a Chrome-Molybdenum alloy (9Cr1Mo) at different temperatures and stress levels. Constitutive equations for creep and rupture master responses are identified for this alloy, and validated based on experimental data. Equivalence transformations are exemplified in the context of parameter reduction in fully nonlinear anisotropic fiber-reinforced elastic solids.
Deep Learning applications for COVID-19
Authors: Shorten Connor , Khoshgoftaar Taghi M. , Furht Borko 
Published: January 2021

AbstractThis survey explores how Deep Learning has battled the COVID-19 pandemic and provides directions for future research on COVID-19. We cover Deep Learning applications in Natural Language Processing, Computer Vision, Life Sciences, and Epidemiology. We describe how each of these applications vary with the availability of big data and how learning tasks are constructed. We begin by evaluating the current state of Deep Learning and conclude with key limitations of Deep Learning for COVID-19 applications. These limitations include Interpretability, Generalization Metrics, Learning from Limited Labeled Data, and Data Privacy. Natural Language Processing applications include mining COVID-19 research for Information Retrieval and Question Answering, as well as Misinformation Detection, and Public Sentiment Analysis. Computer Vision applications cover Medical Image Analysis, Ambient Intelligence, and Vision-based Robotics. Within Life Sciences, our survey looks at how Deep Learning can be applied to Precision Diagnostics, Protein Structure Prediction, and Drug Repurposing. Deep Learning has additionally been utilized in Spread Forecasting for Epidemiology. Our literature review has found many examples of Deep Learning systems to fight COVID-19. We hope that this survey will help accelerate the use of Deep Learning for COVID-19 research.
Racial disparities in mortality after severe traumatic brain injury in childhood: mediators identified by Oaxaca-Blinder decomposition of trauma registry data
Authors: Piatt Joseph 
Published: January 2021

Abstract
Background
In the United States social disparities in health outcomes are found wherever they are sought, and they have been documented extensively in trauma care. Because social factors cannot cause a trauma outcome directly, there must exist mediating causal factors related to the nature and severity of the injury, the robustness of the victim, access to care, or processes of care. An understanding these mediators is the point of departure for addressing inequities in outcomes.

Findings
Data were extracted from the registry of the Trauma Quality Improvement Program of the American College of Surgeons for 2007 through 2010. Inclusion criteria were age less than 19 years and head Abbreviated Injury Scale score of 4, 5, or 6. An Oaxaca-Blinder decomposition was undertaken to analyze the relative contributions of a large set of covariates to the difference in mortality rates between Black and White children. Covariates were aggregated into the following categories: “Severity,” “Structure and Process,” “Mechanism,” “Demographics,” and “Insurance.” Eligible for analysis were 7273 White children and 2320 Black children. There were 1661 deaths (17.3%) The raw mortality rates were 15.6 and 22.8% for White and Black children, respectively. Factors categorized as “Severity” accounted for 95% of the mortality difference, “Mechanism” accounted for 13%, “Insurance” accounted for 5%, and “Demographics” accounted for 2%. The contribution of “Structure and Process” did not attain statistical significance.

Conclusions
Severity of injury accounts for most of the disparity between Black and White children in traumatic brain injury mortality rates. Mechanism, insurance status, and gender make a small contributions. Because insurance status like other social factors cannot directly affect trauma survival, what mediates its contribution requires further study.
Long-period ground motion simulation using centroid moment tensor inversion solutions based on the regional three-dimensional model in the Kanto region, Japan
Authors: Takemura Shunsuke , Yoshimoto Kazuo , Shiomi Katsuhiko 
Published: January 2021

AbstractWe conducted centroid moment tensor (CMT) inversions of moderate (Mw4.5–6.5) earthquakes in the Kanto region, Japan, using a local three-dimensional (3D) model. We then investigated the effects of our 3D CMT solutions on long-period ground motion simulations. Grid search CMT inversions were conducted using displacement seismograms for periods of 25–100 s. By comparing our 3D CMT solutions with those from the local one-dimensional (1D) catalog, we found that our 3D CMT inversion systematically provides magnitudes smaller than those in the 1D catalog. TheMwdifferences between 3D and 1D catalogs tend to be significant for earthquakes within the oceanic slab. By comparing ground motion simulations between 1D and 3D velocity models, we confirmed that observedMwdifferences could be explained by differences in the rigidity structures around the source regions between 3D and 1D velocity models. The 3D velocity structures (especially oceanic crust and mantle) are important for estimating seismic moments in intraslab earthquakes, which are related to fault size estimation. A detailed discussion for intraslab seismicity can be conducted using the 3D CMT catalog. The seismic moments also directly affect the amplitudes of ground motions. The 3D CMT catalog allows us to directly conduct the precise forward and inverse modeling of long-period ground motion without adjusting source models, which have been typically applied in the cases using the 1D CMT catalog. We also conducted long-period ground motion simulations using our 3D CMT solutions to evaluate the reproducibility of long-period ground motions at stations within the Kanto Basin. The simulations of our 3D CMT solutions well-reproduced observed ground motions for periods longer than 10 s, even at stations within the Kanto Basin. The reproducibility of simulations was improved from those using solutions in the 1D catalog.
Assessment of peri-implant tissue dimensions following surgical therapy of advanced ligature-induced peri-implantitis defects
Authors: Ramanauskaite Ausra , Schwarz Frank , Sader Robert , Becker Jürgen , Obreja Karina 
Published: January 2021

AbstractBackgroundTo evaluate peri-implant tissue dimensions following implantoplasty and/or regenerative therapy of advanced ligature-induced peri-implantitis in dogs.Material and methodsAt all defect sites (n= 6 dogs,n= 48 implants), the intrabony component was filled with a particulate bovine-derived natural bone mineral (NBM). The supracrestal component was treated by either the application of an equine bone block (EB) or implantoplasty. In a split-mouth design, NBM and EB were soak-loaded with rhBMP-2 or sterile saline. All sites were covered using a native collagen membrane and left to heal in a submerged position for 12 weeks. The horizontal mucosal thickness (hMT) and bone thickness (hBT) were measured at four reference points: (v0) at the level of implant shoulder (IS), (v1) 50% of the distance IS-bone crest (BC), (v2) at the BC, and (v3) at the most coronal extension of the bone-to-implant contact.ResultsThe general tendency indicated a gradual increase in hMT from the IS (v0) toward BC (v2), which was more pronounced at implant sites treated with the regenerative approach. The hBT values increased from v2 to v3, with the highest values at the v3 region measured for implant sites treated with adjunctive rhBMP-2. For sites treated with implantoplasty, the linear regression model demonstrated an inverse correlation between hMT and hBT, whereas a positive correlation was observed at those sites treated with the regenerative approach.ConclusionHorizontal soft and hard tissue dimensions were similar among different treatment groups.
Effects of Lumbar Spine Abnormality and Serve Types on Lumbar Kinematics in Elite Adolescent Tennis Players
Authors: Connolly Molly , Middleton Kane , Spence Graeme , Cant Olivia , Reid Machar 
Published: January 2021

Abstract
Background
Low back pain (LBP) is pervasive among elite junior tennis players. Previous research has explored the relationship between serving mechanics and LBP, though the participants in these studies had already experienced LBP. Therefore, it is unclear whether their serving mechanics caused the LBP or are a result of having LBP. Thus, the purpose of this study was to compare the flat and kick serve kinematics of asymptomatic elite adolescent male and female tennis players with and without lumbar spine abnormalities. Twenty-four players (nine of which had confirmed lumbar spine abnormalities) carried out a series of flat and kick serves, while marker trajectories were recorded by a 3D motion capture system. Pelvis and lumbar spine kinematics (anterior/posterior tilt, lateral tilt, axial rotation and flexion/extension, lateral flexion and axial rotation respectively) were compared between players with and without lumbar spine abnormalities, genders, and serve types using a mixed-effects model. Exploratory data pertaining to the order and timing of key serve events was also collected.

Results
Males had significantly greater posterior pelvis tilt than females during the drive phase of both flat (M, − 7.1 ± 5°; F, 4 ± 5.5°) and kick serves (M, − 8.6 ± 5.1°; F, 2.1 ± 5.8°). Independent of serve type, males also impacted the ball ~ 15 cm further into the court than females, while all players contacted flat serves significantly further forward (~ 17 cm). There were no effects for abnormality in the magnitude of pelvis and trunk kinematics. The order and timing of key serve events, however, did tend to differ between those with and without lumbar spine abnormalities. Players with abnormalities entered peak front knee flexion and initiated pelvis rotation earlier than players without abnormalities. Lastly, the timing of pelvis rotation was highly variable among females though not males.

Conclusion
Pelvis and ball toss kinematics vary with gender and serve type but not necessarily abnormality in the elite adolescent serve. There is evidence to suggest that the order and timing of key serve events might help to identify those at risk of lumbar spine abnormalities; however, further research is needed to investigate the statistical significance of the timing of these events.
The Association Between Training Load and Injury Risk in Elite Youth Soccer Players: a Systematic Review and Best Evidence Synthesis
Authors: Verstappen Sven , van Rijn Rogier M. , Cost Rick , Stubbe Janine H. 
Published: January 2021

Abstract
Background
Injury risk in elite youth soccer players is high. Implementing an optimal training load is of utmost importance to reduce the risk of injuries.

Objective
To conduct a systematic review and best evidence synthesis to explore the effects of internal and external training load on injury risk in elite youth soccer players.

Methods
MEDLINE, Embase, Web of Science, CENTRAL, and CINAHL were searched up until 17 January 2020. Each article had to meet all of the following criteria: (1) the study population consisted of male elite youth soccer players aged between 12 and 21 years; (2) a longitudinal, prospective study design was used; (3) soccer-related injuries were registered (i.e., self-reported or by medical staff); (4) external and/or internal load parameters were described; and (5) the article was published in an English peer-reviewed scientific journal. The quality of the included articles was assessed using the Newcastle–Ottawa Quality Assessment Scale (NOS). A best evidence synthesis was performed to rank the level of evidence.

Results
Five studies (2 high quality, 3 low quality) were included. Best evidence synthesis highlighted that there was moderate evidence for (1) no association between 2-, 3-, and 4-week cumulative loads for total distance covered; (2) no association between 1-week workloads (sRPE × duration); and (3) no association between A:C workload ratios (4 weeks) and injury risk. For all other comparisons, only insufficient or conflicting evidence was found.

Conclusion
There is a paucity of evidence for an association between internal and external training load parameters and injury risk in elite youth soccer players.
Ocular complications following intravitreal bevacizumab injection for retinopathy of prematurity and assessment of risk factors
Authors: Bazvand Fatemeh , Riazi-Esfahani Hamid , Mirshahi Ahmad , Khodabande Alireza , Khojastheh Hasan , Farahani Afsar Dastjani , Roohipourmoallai Ramak , Imani Marjan , Faghihi Hooshang , Adib Nazanin Ebrahimi , Bahar Mohammadreza Mehrabi 
Published: January 2021

Abstract
Purpose
Laser ablation of the avascular peripheral retina has been the standard method of ROP treatment. Intravitreal anti-VEGF is useful in the management of ROP patients, especially for aggressive posterior ROP. However, ocular and systemic complication after intravitreal bevacizumab was the main concern. This study aimed to investigate the treatment-related ocular and systemic complications of intravitreal bevacizumab (IVB) in patients with retinopathy of prematurity (ROP).

Method
This retrospective study included neonates receiving intravitreal injections of bevacizumab (IVB) (0.625 mg) to treat ROP. Medical records of the patients were evaluated about the ocular complications after receiving IVB from 2012 to 2019. Treatment-related complications (vitreous hemorrhage, glaucoma, cataract, hyphema, corneal abrasion/opacity, and endophthalmitis), and disease-progression signs including retinal fold or stage 4 or 5 detachment were documented. Any reports of systemic events after injections were also recorded.

Result
Mean gestational age and birth weight of 441 patients receiving IVB for type-1 ROP were 28 ± 2 (22–34 weeks) and 1121 ± 312 (550–2700 g), respectively. The median follow-up after treatment in all patients and patients with complications was 289.43 ± 257 days (5–1899 days) and 385.89 ± 311.59 (196–1192) days, respectively. Out of 865 eyes, 20 eyes (2.31%, 95% Clopper-Pearson Confidence Interval: 1.14–3.54%) have been affected by ocular complications. The rates of different complications included progression of retinopathy in 17 eyes (1.96%), cataracts in 2 eyes (0.23%), and vitreous hemorrhage in one eye (0.11%). No cases of endophthalmitis, thromboembolic events, or death occurred in this study. We evaluated the prevalence ratio (PR) on the multiple risk factors to determine the prediction of the complications. The existence of neovascularization of iris has the highest susceptibility to predict the complication (PR = 5.091, P-value 0.014) following by the presence of retinopathy in zone 1 of the infant’s retina (PR = 4.386, P-value = 0.010).

Conclusion
The incidence rate of complications related to Intravitreal bevacizumab injection was low, which was compatible with previous studies. Bevacizumab injection seems well tolerated in most cases of ROP. Iris neovascularization and the presence of retinopathy in zone 1 were associated with a higher occurrence of complications than the absence of these risk factors.
Diagnostic accuracy of the clinical indicators to identify central sensitization pain in patients with musculoskeletal pain
Authors: Bittencourt Juliana Valentim , de Melo Magalhães Amaral Ana Carolina , Rodrigues Pedro Vidinha , Corrêa Leticia Amaral , Silva Bruno Moreira , Reis Felipe José Jandre , Nogueira Leandro Alberto Calazans 
Published: January 2021

AbstractBackgroundThe identification of central sensitization (CS) is an important aspect in the management of patients with chronic musculoskeletal pain. Several methods have been developed, including clinical indicators and psychophysical measures. However, whether clinical indicators coincide with the psychophysical test of CS-related sign and symptoms is still unknown. Therefore, the present study aimed to analyze the diagnostic accuracy of the clinical indicators in identifying CS-related sign and symptoms in patients with musculoskeletal pain.MethodsOne-hundred consecutive patients with musculoskeletal pain were included. Clinical indicators (index method) based on a combination of patient self-report pain characteristics and physical examination were used to identify the phenotype of patients with musculoskeletal pain and the predominance of the CS-related sign and symptoms. Conditioned pain modulation (CPM) was assessed by the Cold Pressor Test (reference standard), which is a psychophysical test used to detect impairment of CPM. Measurements of the diagnostic accuracy were performed.ResultsTwenty-seven patients presented predominance of CS-related sign and symptoms in the assessment of the clinical indicators, and 20 had impairment of CPM. Clinical indicators showed high accuracy (75.0%; 95% confidence interval = 65.3 to 83.1), high specificity (80.0%; 95% confidence interval = 69.6 to 88.1), high negative predictive value (87.7%; 95% confidence interval = 81.2 to 92.1), and a relevant positive likelihood ratio (2.8, 95% confidence interval = 1.5 to 5.0) when compared to the Cold Pressor Test.ConclusionClinical indicators demonstrated a valuable tool for detecting the impaired CPM, which is a remarkable feature of the CS-related sign and symptoms. Clinicians are encouraged to use the clinical indicators in the management of patients with musculoskeletal pain.
Rescue permanent LVIS stenting with post-stenting angioplasty after failed mechanical thrombectomy for refractory internal carotid artery occlusion at the paraclinoid segment: two-case report
Authors: Li He , Li Zifu , Hua Weilong , Zhang Yongxin , Yang Wenjin , Feng Mingtao , Zhang Lei , Xing Pengfei , Zhang Yongwei , Hong Bo , Yang Pengfei , Liu Jianmin 
Published: January 2021

Abstract
Background
Previous studies indicated the effectiveness of permanent stenting when dealing with retriever-failed refractory large vascular occlusion (LVO). Variety types of stents were implanted permanently to achieve recanalization. Low-profile visualized intraluminal support (LVIS) is generally used as a supportive device for embolization of intracranial aneurysm. Its specific structural and functional characteristics contribute to its potential of treating LVO.

Cases presentation
A 51-year-old male was transferred to our stroke center because of conscious disturbance with the weakness of the left upper limb. The National Institute of Health Stroke Scale (NIHSS) was 24; the Glasgow Coma Scale (GCS) was 10. Digital subtraction angiography (DSA) showed that his paraclinoid segment of R-ICA was occluded due to hard clot embolization. Thrombectomy was performed 6 times, but the occlusion remained. Finally, LVIS was implanted permanently and post-dilation was performed, which successfully recanalized the artery (eTICI 2c). The post-operative NIHSS and GCS were 20 and 11, respectively, which were 10 and 14 when discharged.
Another patient was a 71-year-old male who suffered weakness of left limbs. NIHSS was 15; GCS was 11. DSA confirmed that the paraclinoid segment of his R-ICA was occluded due to hard clot embolization. Totally 6 times of mechanical thrombectomy, angioplasty, and tirofiban infusion were performed, which failed to recanalize the artery. In the end, LVIS implantation with post-dilation was performed, and full recanalization was achieved (mTICI 3). The post-operative NIHSS and GCS were 9 and 15, respectively, which were 3 and 15 when discharged.

Conclusions
These 2 cases invited LVIS into the treatment of refractory occlusion due to hard clot embolization at the paraclinoid segment, and the outcomes were preferable because of the higher visibility, higher flexibility, and lower cell size of LVIS.
Psychometric examination of Runco Ideational Behavior Scale: Thai adaptation
Authors: Tep Puthyrom , Maneewan Sorakrich , Chuathong Saranya 
Published: January 2021

AbstractCreativity is a multidimensional construct. Several different approaches have been developed to measure creativity, including psychometric scales. The Runco Ideational Behavior Scale (RIBS) is one such measure of creative ideation. The primary purpose of this paper was to assess the 23 items of the RIBS in the context of the Thai language and examine scale reliability and validity. Participants, consisting of 508 undergraduate students selected from five Thai public universities, were selected through a convenience sampling approach involving both exploratory and confirmatory factor analysis. Results suggested that the Thai version of the RIBS presented a valid measure to a certain extent. Factor analysis of the empirical data indicated a two-dimensional structure. Confirmatory factor analysis (CFA) results confirmed that the two-factor construct demonstrated a better fit with improved psychometric characteristics. Six items were eliminated from the Thai RIBS version inventory: five items during explanatory factor analysis (EFA) and one during the CFA process. Results will contribute to ascertaining that the Thai version of the RIBS instrument can be used as a self-assessment tool for measuring students’ creative ideation. Implications and limitations of this research are discussed with suggestions for future studies.
Congenital portosystemic shunt occlusion with an Amplatzer PFO occlusion device: a case report
Authors: Shnayder Michelle M. , Dervishi Mario , Jo Alexandria , Pomerantz Benjamin 
Published: January 2021

Abstract
Background
Congenital portosystemic shunts are embryological malformations in which portal venous flow is diverted to the systemic circulation. High morbidity and mortality are seen in patients with concurrent hepatic encephalopathy, hepatopulmonary syndrome, and pulmonary hypertension. Endovascular therapy, in the correct patient population, offers a less invasive method of treatment with rapid relief of symptoms.

Case presentation
In this report, we discuss the treatment of a two-year-old male with abnormal chorea-like movements, altered mental status, anisocoria and hyperammonemia diagnosed with an intrahepatic congenital portosystemic shunt between the inferior vena cava and right portal vein. Given the patient’s amenable anatomy and shunt type, embolization was performed with an 18 mm Amplatzer patent foramen ovale occlusion device.

Conclusions
Portosystemic shunts are a rare congenital abnormality without universal treatment guidelines. An Amplatzer PFO occlusion device can provide a novel method of shunt closure given appropriate shunt type, size and anatomy.