bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on Fracture Characteristics and Controlling Factors of Tight Sandstone Reservoir: A Case Study on the Huagang Formation in the Xihu Depression, East China Sea Shelf Basin, China
Authors: Zhao Zhongxiang , He Youbin , Huang Xin 
Published: July 2021

Abstract
Natural fractures are not only the key to affect the natural productivity of tight sandstone reservoirs but also one of the important factors to control the fracturing effect. If the local strata are affected by multistage tectonic movement and diagenesis, it will lead to the complexity of fracture types and characteristics, which makes it difficult to accurately identify natural fractures, thus, seriously affect the development of fractured reservoirs and the fracturing effect. In this paper, the macroscopic fractures were studied by combining core, conventional logging, imaging logging, petrophysical logging, logging, drilling, and gas test data. The microscopic fractures were analyzed by casting thin sections and scanning electron microscopy and cathodoluminescence. The effect of fractures on hydrocarbon migration was analyzed by fluid inclusions in fractures. The core can be used to visually study the opening fracture, but when the color of the filling inside the fracture is similar to the surrounding, the filling fracture is not easy to be found. Imaging logging has high identification accuracy for filling fractures, but it can hardly be used as a means of identifying high-angle opening fractures. The opening fracture zone in the noncoring section can be studied by conventional logging, mud logging, drilling, and rock mechanical parameter. The macroscopic structural fractures are obviously directional, which is controlled by the tectonic stress field. The occurrence and density of macroscopic structural fractures are controlled by buried depth, lithology, rock thickness, sedimentary facies, distance from the fault, and structural location. The opening fractures are all of high angle, indicating that the inclination angle is an important factor affecting the filling degree of fractures. The direction of intragranular fractures is chaotic, which is affected by the mechanical weak surface of the mineral particles, particle morphology, and particle contact relationship and stress. Effective fractures provide channels for the migration of oil and gas and acidic fluids in the historical period, which promote the occurrence of hydrocarbon accumulation and dissolution.
Experimental Investigation and Numerical Simulation of Dynamic Characteristics for Multithermal Fluid-Assisted SAGD in Extraheavy Oil Reservoir
Authors: Xu Zhenhua , Zhang Xiaokun , Cao Zhenyi , Liu Pengcheng , Yuan Zhe , Shi Lanxiang , Kang Botao 
Published: July 2021

AbstractLoss of the vast majority of heat and steam is an unavoidable problem encountered during conventional steam-assisted gravity drainage (SAGD) in extraheavy oil reservoirs. The noncondensate gas coinjection technique of reducing energy consumption and enhancing oil recovery can effectively solve this problem. Aiming at extraheavy oil with a high initial viscosity, the influence of noncondensate gases in multithermal fluids on the physical parameters of extraheavy oil was experimentally studied; the production characteristics and mechanism of multithermal fluid-assisted SAGD were studied through numerical simulation. A comparative investigation of the conventional SAGD and multithermal fluid-assisted SAGD injection schemes was conducted. The characteristics and mechanism of the steam chamber during the production processes were analyzed. The results show that a steam-gas-oil system forms in the steam chamber in the case of multithermal fluids. The steam chamber can be partitioned into four zones, and the flow of the oil mainly occurs in the steam condensation zone and the oil drainage zone. The injected multithermal fluids increase the horizontal expansion of the steam chamber, while the dissolved carbon dioxide reduces the residual oil saturation. Moreover, the nitrogen injection significantly reduces the heat loss and increases the heat utilization for multithermal fluid-assisted SAGD in developing extraheavy oil reservoirs.
Studying the treatment processes of soil samples from radionuclides
Authors: Mammadov Khagani Farzulla , Shiraliyeva Hajar Nuhbala , Mehtiyev Elnur Ismikhan , Aliyeva-Jabbarly Ulviyya Salam , Guliyev Elchin Ilham , Mirzayev Nijat Agil , Huseynova Aynur Huseyn 
Published: July 2021

Object of research: Soil samples contaminated with radionuclides and processes for treatment of contaminated soil.
The problem to be solved: Isolation of radionuclides from contaminated soil samples by extraction with weak solutions of acids and alkalis.
Main scientific results: Treatment of soil samples contaminated with uranyl nitrate using extraction with weak solutions of nitric and hydrochloric acid, caustic sodium and subsequent washing of soil residues with distilled water is effective process and leads to a more than tenfold decrease in the content of uranium isotopes (U238, U235, U234 and U236) in the soil samples. At the same time, there is a decrease in the content of natural radionuclides (Na22, K40, Zn65, Sn113, Sn126) in the extracted soil samples. An increase in their content in the extract of the analyzed soil samples corresponds to a decrease in their content in the residue of the extracted soil samples. The analysis of the values of the decrease in the content of natural radionuclides in the soil contaminated with uranyl nitrate corresponds to the values of the decrease in their content in the identical soil, but not contaminated with uranium isotopes. The combined extraction with weak solutions of acids and alkalis leads to the enrichment of the soil with nitrates and chlorine-containing compounds.
The area of practical use of the research results: Subdivisions of the Ministry of Emergency Situations and Chemical Troops specializing in the study of emergencies and natural disasters can use the results of these studies in the elimination of the consequences of global environmental disasters and incidents that pose a threat to the life of the civilian population and the personnel of paramilitary units.
Innovative technological product: The proposed method for treatment of soil contaminated with radionuclides makes it possible to more than tenfold reduce their concentration in the soil.
Scope of application of an innovative technological product: treatment of contaminated soil in areas affected by nuclear tests or accidents at nuclear power plants.
Institutional analysis of top-down regulatory: evidence from Iran local governance
Authors: Kamal Mohamad M. , Amiri Hadi , Moghadam Vahid , Rahimi Dariush 
Published: July 2021

Abstract
Population growth, along with climate change, has exacerbaed the water crisis in local communities. The simplest and quickest response of governments to such problems is direct intervention in local governance. Such solutions are usually proposed without regarding the indigenous knowledge of the local people. These also include top-down policies on water issues, which disrupt local institutional arrangements and eliminate the possibility of collective action by stakeholders in reaching an agreement. A case study of one of the water basins in Chaharmahal Bakhtiari in Iran (the Gorgak River in Sureshjan city) using an institutional analysis and development (IAD) framework shows that in the past, people acted collectively to solve the asymmetric distribution and drought problem. But government intervention, which initially sought to improve water conditions, has disrupted the region's institutional arrangements and power asymmetries between exploiters. Our study used the IAD framework to examine changes in institutional arrangements due to the introduction of technology and government intervention by the game theory. It clarifies that government intervention in local institutional arrangements, even if designed with the intention of improving conditions, may lead to greater inequality due to disregarding physical and social conditions and local knowledge. This inequality can eventually worsen the situation.
Efficient removal of ammoniacal nitrogen from textile printing wastewater by electro-oxidation considering the effects of NaCl and NaOCl addition
Authors: Cifcioglu-Gozuacik Bengisu , Ergenekon Sinem Merve , Ozbey-Unal Bahar , Balcik Cigdem , Karagunduz Ahmet , Dizge Nadir , Keskinler Bulent 
Published: July 2021

AbstractIn this study, an electro-oxidation (EO) process using graphite electrodes as electrode pairs was used for the removal of chemical oxygen demand (COD), ammoniacal nitrogen (NH4+-N), and color from real textile printing wastewater. The effects of solution pH, sodium chloride (NaCl) dosage, sodium hypochlorite (NaOCl), which is the oldest and still most important chlorine-based bleach, dosage, and oxidation time were investigated on the removal efficiencies. Operating conditions for the EO reactor were applied to current density 1 mA/cm2, distance between the electrodes: 2 cm, 150 min operation time, and stirring speed of 500 rpm. At optimum conditions: pH 9.5, applied current density 1 mA/cm2, NaCl dosage of 8 g/L, NaOCl dosage of 44.4 mg/L and 150 min electro-oxidation time, the obtained removal efficiencies were 86.5% and 91.1% for chemical oxygen demand (COD) and ammoniacal nitrogen, respectively. Efficiency was increased to 91.1% for ammoniacal nitrogen from 21.7% after applying EO combined with NaOCl addition compared to individual NaOCl addition.
Evaluation and Clinical Implication of Zhenwu Decoction on Seven Cytochrome P450 Enzyme in Chronic Heart Failure Rats
Authors: Hong Li-Li , Wang Hong-Song , Cheng Xiao-Yu , Zhang Sheng , Zhao Yan , Wang Qian , Zhao Ya-TIng , Wang Lei , Ge Lan , Su Jun , Chen Wei-Dong 
Published: July 2021

Background:
Recently, the combination of Traditional Chinese Medicine (TCM) formulae and other
drugs has been used frequently in clinical practice, while the possibility of herb-drug interaction (HDI) risk remains a
challenge. Since metabolic enzymes mediate the majority of drug interactions, evaluating the effects of formulae on
metabolic enzymes is therefore instructive for the rational formulation of drug delivery plans.

Objective:
Herein, we are devoted to estimating the effects of Zhenwu detection (ZWD) on activities and mRNA
expression of 7 cytochrome P450 (CYP450) isoenzymes in chronic heart failure (CHF) rats.

Methods:
The CHF rats were replicated by coronary artery ligation and were randomly divided into sham operation
group, model group, ZWD low- (2.188 g/kg), middle- (4.375 g/kg), and high- (8.750 g/kg) dose groups, n=6. After 8
weeks, rats were administrated with ZWD and normal saline (NS) for four weeks, and the mixed solution of 7 probe
drugs (1 mL/kg) was subsequently injected into 30 rats through the caudal vein after the last administration. Pharmacokinetic
parameters and mRNA expression of 7 probe drugs were measured by using UPLC-MS/MS and RT-qPCR,
respectively.

Results:
Activities and mRNA expression of CYP1A2, CYP2B1, CYP2C6, CYP2C11, CYP3A1 were inhibited in
CHF rats, and ZWD could reverse this effect except for CYP2B1.

Conclusion:
Overall, these findings underscore that for CHF patients, the HDI should be taken into consideration
when ZWD is used on its own or combined with drugs meditated by CYP1A2 (CYP1A2 in rats), CYP2C9 (CYP2C6
in rats), CYP2C19 (CYP2C11 in rats) and CYP3A4 (CYP3A1 in rats). Furthermore, since the apparent volume of
distribution (Vd) of amodiaquine, dextromethorphan and bupropion has been proved to be far greater than the total
volume of body fluids, we speculate that the dose adjustment and potential organotoxicity of these substrates may
need further consideration.
Outpatient Psychotropic Drug Interactions in a Public Psychiatry Hospital
in Bahrain: An Audit Study
Authors: Tayem Yasin , Aljaberi Saeed , Alfehaid Ali , Almekhyal Abdulaziz , Jahrami Haitham , Ali Mazen , Hattab Suhaib 
Published: July 2021

Background:
Psychotropic polypharmacy is particularly common, which puts psychiatric
patients at high risk for developing drug-drug interactions.

Objective:
We aimed to study potential interactions between psychotropic medications prescribed
within the outpatient psychiatry setting.

Method:
This was an audit study, which targeted a sample of outpatient prescriptions ordered
within the outpatient clinics of the main psychiatry hospital in Bahrain over 2017. We studied the
grades and correlates of interactions between psychotropic drugs.

Results:
The total number of prescriptions in our sample was 992 (56.1% males, 43.9% females).
Psychotropic polypharmacy was detected in 842 prescriptions (84.9%). Potential interactions between
psychotropic drugs were observed in 550 prescriptions (56.4%). The degree of interaction
was minor in 43 prescriptions (7.8%), significant in 419 prescriptions (76.2%), and serious in 88
prescriptions (16%). Schizoaffective disorder subjects were the most likely to suffer from interactions
(64.6%), whereas prescriptions issued for those who had schizophrenia contained the least
number of interactions (51.6%). The total number of interactions was strongly associated with polypharmacy
(p < .001) and gender (p < .01), but not with age (p > .05) or diagnosis (p > .05).

Conclusion:
High prevalence of polypharmacy and interactions between psychotropic medications
were observed in our sample, particularly of the significant grade.
Heart failure with preserved ejection fraction in patients with type 2 diabetes mellitus: pathophysiology and treatment options
Authors: Borisov A. A. , Gvozdeva A. D. , Ageev F. T. 
Published: July 2021

Type 2 diabetes mellitus is known to increase the risk of the development of heart failure with preserved ejection fraction and worsen its symptoms. To date, no specific treatment has been shown to reduce morbidity and mortality in patients with heart failure with preserved ejection fraction. In this review, the authors summarized the existing evidence on how diabetes mellitus can promote the development and progression of heart failure with preserved ejection fraction. The authors also addressed medications including experimental ones that can potentially be beneficial in patients of this group.
Exploring Test-Retest Reliability and Longitudinal Stability of Digital Biomarkers for Parkinson Disease in the m-Power Data Set: Cohort Study
Authors: Sahandi Far Mehran , Eickhoff Simon B , Goni Maria , Dukart Juergen 
Published: July 2021

Background
Digital biomarkers (DB), as captured using sensors embedded in modern smart devices, are a promising technology for home-based sign and symptom monitoring in Parkinson disease (PD).

Objective
Despite extensive application in recent studies, test-retest reliability and longitudinal stability of DB have not been well addressed in this context. We utilized the large-scale m-Power data set to establish the test-retest reliability and longitudinal stability of gait, balance, voice, and tapping tasks in an unsupervised and self-administered daily life setting in patients with PD and healthy controls (HC).

Methods
Intraclass correlation coefficients were computed to estimate the test-retest reliability of features that also differentiate between patients with PD and healthy volunteers. In addition, we tested for longitudinal stability of DB measures in PD and HC, as well as for their sensitivity to PD medication effects.

Results
Among the features differing between PD and HC, only a few tapping and voice features had good to excellent test-retest reliabilities and medium to large effect sizes. All other features performed poorly in this respect. Only a few features were sensitive to medication effects. The longitudinal analyses revealed significant alterations over time across a variety of features and in particular for the tapping task.

Conclusions
These results indicate the need for further development of more standardized, sensitive, and reliable DB for application in self-administered remote studies in patients with PD. Motivational, learning, and other confounders may cause variations in performance that need to be considered in DB longitudinal applications.
Web- and Mindfulness-Based Intervention to Prevent Chronic Pain After Cardiac Surgery: Protocol for a Pilot Randomized Controlled Trial
Authors: Martorella Geraldine , Hanley Adam W , Pickett Scott M , Gelinas Céline 
Published: July 2021

Background
Cardiac surgery is a frequently performed procedure. However, pain after cardiac surgery may become chronic (lasting >3 months) in adults. Once discharged from the hospital, patients are at greater risk of developing chronic postsurgical pain (CPSP) and of prolonged opioid use, as they need to self-manage their pain. Psychological risk and protective factors such as pain-related catastrophic thoughts and pain acceptance determine their ability to cope and their use of opioids, which is crucial for self-management of pain. Studies on mindfulness-based cognitive therapy (MBCT) have multiplied their potential effects on pain acceptance and catastrophic thoughts. However, web-based MBCT for the prevention of CPSP has not yet been examined.

Objective
The aim of this study is to pilot test a 4-week-long web-based MBCT intervention for adults following discharge from the hospital by assessing the acceptability or feasibility of the intervention and examining preliminary effects on pain intensity, pain interference with activities and opioid use, and pain acceptance and catastrophic thoughts in the 6 months following surgery.

Methods
A double-blinded pilot randomized controlled trial will be used to assess a web-based MBCT intervention. Patients will be selected according to the following criteria: age ≥18 years; first-time elective cardiac surgery via a median sternotomy; worst pain in the past week score ≥4/10; ability to understand and complete questionnaires in English; and ability to use an electronic device such as a smartphone, computer, or tablet. After baseline measures, 32 participants will be randomized into two groups: one receiving both the brief, 4-week-long web-based MBCT intervention and usual care (experimental group) and the other receiving only one standardized, web-based educational session with weekly reminders and usual care (attention control group). Peer-reviewed competitive funding was received from Florida State University’s Council on Research & Creativity in January 2021, as well as research ethics approval from Florida State University's institutional review board.

Results
Recruitment began in June 2021. Unfortunately, because of the current COVID-19 pandemic, recruitment is not progressing as expected. Recruitment strategies are constantly monitored and updated according to latest data and restrictions surrounding the pandemic.

Conclusions
This research is significant because it targets the trajectory of CPSP, a leading cause of disability and opioid misuse. This is the first study to assess MBCT for the prevention of CPSP after cardiac surgery in the recovery phase. This approach is innovative because it promotes self-management of pain through the modulation of individual factors. If successful, the intervention could be expanded to numerous populations at risk of chronic pain.

International Registered Report Identifier (IRRID)
DERR1-10.2196/30951
Polarization of Profit Sharing of Paddy Cultivation in the Acehnese Community as an Attempt to Alleviate Poverty: A Study of Fiqh Muamalah
Authors: Maulana Muhammad , Amri Aulil 
Published: July 2021

This study examines the polarization of profit sharing in paddy cultivation in the tradition of the people of Aceh as an effort to alleviate poverty. This study, as the empirical or juridical sociological legal research, examines the behavior of law or operation of law in society. The study uses fiqh muamalah approach and obtains data through interviews and literature study. This study concludes that the pattern of profit sharing on the cultivation of paddy fields is categorized into a muzāra’ah aqd, which has rules specified in fiqh muamalah and promotes mutual assistance. However, traditionally, the people of West Aceh, Pidie, and Aceh Jaya utilizing leasing in managing paddy fields tend not to fully operate in accordance with the muzāra’ah aqd. This is due to the operational costs needed for the management of the fields have to be provided by the tenant farmers without financial contributions from the landowners at all. This method can easily allow the landowners to exploit the labor of tenant farmers as the tenants do not have other options aside from cultivating the land. As a result, tenant farmers find it difficult to get out of the shackles of poverty. Therefore, it takes effort to help the farmers out of poverty. It is expected that the government plays a role in the forms of the provision of aids such as seeds, fertilizers, medicines, harvesting machines, and rice threshers, with the goal to reduce expenditure costs of management and thus, the farming revenue will increase and farmers’ well-being will be achieved.
A Comparative Analysis of DSN-MUI Fatwas Regarding Murabahah Contract and the Real Context Application (A study at Islamic Banking in Aceh)
Authors: Ibrahim Azharsyah , Salam Abdul Jalil 
Published: July 2021

The National Sharia Council-Indonesian Ulama Council (DSN-MUI) has issued 11 fatwas (a formal ruling on a point of Islamic law) related to murabahah for parties in economic transactions. However, in the initial study, several indications of the dissonance between the clauses in the fatwa and the practice of Islamic banking were found. This study aims to analyze the application of murabahah contracts in Islamic banking in Aceh. Several Fatwas declared by the National Sharia Council - Indonesian Ulama Council (DSN-MUI) that are related to murabahah were used as an analytical tool to assess the shariah value of the contract in financing practice at Islamic banking in Aceh. This study used a descriptive qualitative method, particularly, a critical study approach. Data were collected using: 1) interviews with bank employees and customers, 2) participant observation in which researchers were directly involved in the process of financing application at several Islamic banks, and 3) documentation studies of resources related to the fatwas. The results showed that the practice of murabahah financing conducted by Islamic banking in Aceh was not fully in accordance with the fatwas stipulated by the DSN-MUI. The results of the analysis showed that the discrepancy lies in the following matters such as ownership of goods, 'coercion' in the use of murabahah contracts, and the inappropriate use of 'wakalah'or contract assistant. The study also revealed that the practice of murabahah in this method has both positive and negative economic implications for banking customers and the banks, especially with regards to profits, calculations of credit ceiling, and customers’ image and trust.