bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pharmacologic Alteration of Corneal Topography After Radial Keratotomy
Authors: Kwitko Sergio , Sinbawy Abdelhamid , Lee Martha , McDonnell Peter J 
Published: April 2021

ABSTRACT
Contraction of corneal wounds as the incisions heal may account for changes in corneal topography after radial keratotomy; such contractility of avascular corneal wounds has been demonstrated in vitro. Using a cat model of radial keratotomy, we demonstrated in vivo contractility of radial keratotomy incisions. In eight eyes of adult female cats, four-incision radial keratotomies were performed, producing central corneal flattening. After 3 and 8 days, serotonin (1 mg/mL) was applied. On day 3, application of topical serotonin resulted in corneal steepening (P < .0001); serotonin produced no topographic changes when applied on day 8 and had no effect on normal unoperated corneas. Vehicle produced no change in corneal curvature before or at any time after radial keratotomy. Fluorescence microscopy revealed cells with myofibroblastic differentiation at the incisions. These data suggest that cells with contractile abilities play a role in determining corneal topography after radial keratotomy.
Visual, Astigmatic, and Inflammatory Results With the Staar AA-4203 Single-Piece Foldable IOL: A Randomized, Prospective Study
Authors: Martin Robert G , Sanders Donald R 
Published: April 2021

ABSTRACT
One hundred twelve unilateral cataract extraction patients were randomly assigned to receive either a one-piece Staar Model AA-4203 silicone intraocular lens (IOL) implanted through a 3.2-millimeter incision, or a one-piece polymethylmethacrylate IOL implanted through a 6.0-millimeter incision. Follow up was 96% at 1 day postoperatively, 90% at 3 months, and 70% at 1 year. Fifty-three percent of the eyes that received a smaller incision could see 20/40 or better uncorrected at 1 day, as compared with 19% of the eyes that received a 6-millimeter incision (P < .01). At 3 months, significantly more smaller-incision eyes could still see 20/40 or better (P = .03). The smaller-incision eyes also had significantly less surgically-induced astigmatism at both 1 day (P < .01) and 3 months (P = .02), and had significantly less flare (P < .01) and cellular reaction (P = .04) at 1 day.
Surgical Treatment and Desensitization Therapy of Giant Papillary Allergic Conjunctivitis
Authors: Del Prete A , Chiosi E , Magli A , Calandriello M , Bernardo B , Bracale G 
Published: April 2021

ABSTRACT
We found that three cases of giant papillary conjunctivitis responded well to local specific desensitization therapy and transplantation of the conjunctiva with saphenous vein tissue.
Adjunctive Viscoelastic Therapy for Postoperative Ciliary Block
Authors: Juzych Mark S , Parrow Kyle A , Shin Dong H , Swendris Ronald P , Ramocki John M 
Published: April 2021

ABSTRACT
Following Molteno device implantation, trabeculectomy, or needling revision of trabeculectomy, six eyes of six chronic glaucoma patients developed a flat anterior chamber without hypotony, ciliochoroidal detachment, pupillary block, or external wound leak. The ciliary block did not respond to vigorous medical and laser therapy. We performed an intracameral injection of sodium hyaluronate, which resulted in maintenance of a full anterior chamber and normal intraocular pressure in all of the six eyes. The use of intracameral viscoelastic appears to be a reasonable adjunct for management of ciliary block not responsive to vigorous medical therapy and intracameral air injection trial, before attempting more extensive surgery.
Nasal Secretions in Ocular Surgery Under General and Local Anesthesia
Authors: Nagle F , Cooper R L 
Published: April 2021

ABSTRACT
To investigate the etiology of nasopharyngeal secretion reflux under anesthesia, which could contaminate the conjunctiva, we photographed, after preoperative nasal instillation of fluorescein, the faces of 224 consecutive patients having cataract surgery under general (n = 78) and local (n = 146) anesthesia. In 10 patients, extension of the neck and facial contour caused fluid to drain from the nose directly into the conjunctival cul-de-sac. Nine of the 78 patients under general anesthesia had nasal secretions on the face at the end of surgery, usually due to leaking around the endotracheal tube. Adjusting head posture by moderate neck flexion and taking care to prevent leakage around the endotracheal tube, together with antiseptic preparation of the nose, may prevent contamination of the operative field by nasal secretions.
Measured and Predicted Anterior Chamber Depth for Transscleral Suture-Fixated Posterior Chamber Intraocular Lenses
Authors: Corder Donna M , McDermott Mark L , Shin Dong H , Parrow Kyle A , Lau-Sickon Laurie K 
Published: April 2021

ABSTRACT
Variables in intraocular lens (10L) power calculations include axial length, average dioptric power of the cornea, and an assumed Pseudophakie anterior chamber depth (ACD). In the case of transscleral suturefixated posterior chamber (PC) IO Ls, ACD depends on the placement of the suture and thus might be expected to vary more than it does in eyes with capsular-fixated IOLs. To assess the degree of this variation, we determined the postoperative Pseudophakie ACD using ?-scan ultrasonography in 15 patients with transscleral suture-fixated PC-IOLs. The mean Pseudophakie ACD (posterior corneal vertex to anterior pseudophakos) was 3.47 ± 0.69 mm. The mean absolute discrepancies in ACD between these measured values and those predicted by the original Binkhorst and the most recent Holladay formulas were 0.579 ± 0.513 mm and 0.639 ± 0.519 mm, respectively. In 11 of 15 eyes, the measured ACD was within 1 mm of that predicted by either the Binkhorst or Holladay formula, suggesting that either will provide reasonable estimates of ACD for IOL power calculations for suture-fixated PC-IOLs.
Surgical Management of a Long-Standing Subfoveal Neovascular Membrane Secondary to Ocular Histoplasmosis
Authors: Wind Brian E , Sobol Warren M 
Published: April 2021

ABSTRACT
Subretinal neovascular membranes located under the fovea typically lead to significant visual loss. Laser treatment has been limited due to the anatomic location of the neovascular process, but surgical removal has been reported with promising results. We surgically removed a long-standing, presumed ocular histoplasmosis syndrome (POHS) subfoveal neovascular membrane that had been present for 10 months in a patient's only functional eye, with unexpected good results. This case suggests that the good visual outcomes achieved by surgically excising smaller subfoveal neovascular membranes early in their natural history also can be achieved in selected patients with more chronic and severe subfoveal neovascular processes.
A New Method for Posterior Sub-Tenon's Drug Administration
Authors: Nesterov Arkady P , Basinsky Sergey N , Isaev Ajubkhan 
Published: April 2021

ABSTRACT
We describe a technique of sub-Tenon's drug administration involving the use of a strip of collagen sponge connected with a silicone tube. The strip is implanted in the sub-Tenon's space and the free end of the tube "is attached to the patient's forehead. Medication is infused through the tube two to four times a day for 7 to 10 days; then the tube is removed. We have used this technique, without serious complications, in the treatment of 230 patients with various diseases of the posterior segment and the anterior part of the optic nerve.
Mersilene Mesh and Fascia Lata in Brow Suspension: A Comparative Study
Authors: Elder Mark J 
Published: April 2021

ABSTRACT
I retrospectively compared 34 brow suspension procedures: 17 using Mersilene mesh and 17 using stored, irradiated fascia lata. Good results were obtained with both materials. Since Mersilene mesh is inexpensive, easy to prepare and work with, and can be sterilized and guaranteed free of infectious diseases, it is an acceptable alternative if fascia lata is unavailable.
Curved, Sub-Tenon Cannula for Local Anesthesia
Authors: Stevens Julian D 
Published: April 2021

ABSTRACT
I describe a new cannula for delivery of sub-Tenon's local anesthetic solution. The cannula has a rigid structure, a 19-gauge diameter, and a shaft with a gentle curve, specifically designed to follow the contour of the globe. Anteroposterior flattening of the tip facilitates advancement of the cannula within the potential Tenon's-space tissue plane. Without the acute angulation of the shaft of the Bishop-Harmonstyle cannula, it is easier to follow the gtobe contour and create less tenting-up of conjunctiva.
Mitomycin as Adjunct Therapy in Correcting Iatrogenic Punctal Stenosis
Authors: Lam Sheridan , Tessler Howard H 
Published: April 2021

ABSTRACT
A 52-year-old woman developed persistent epiphora in her left eye after undergoing occlusion of the left puncta. Two attempts to reopen the puncta with a one-snip procedure and placement of punctal sii icone plugs failed. The epiphora resolved and the puncta remained patent after the patient underwent a third one-snip procedure, supplemented with topical mitomycin during and after surgery.
Systemic Herpetic Infection Diagnosed by Retinal Biopsy
Authors: Friedberg Mark A , Schwartz Joseph C , Feinman Mitchell C , Pilkerton A Raymond , Barth Werner F , Perman Kevin I 
Published: April 2021

ABSTRACT
We describe a patient with systemic lupus erythematosus who developed myelopathy, optic neuropathy, retinopathy, and aseptic meningitis unresponsive to immunosuppressive and antimicrobial therapy. Although cultures and brain biopsy were unrevealing, a Herpes virus was suggested by retinal biopsy. The patient recovered dramatically after institution of acyclovir therapy and optic-nerve-sheath decompression. This case demonstrates that herpetic retinitis can occur in an iatrogenically suppressed host and underscores the value of tissue diagnosis.
Versatility of the cw-Nd:YAG and Diode Lasers in Ocular Surgery
Authors: Fankhauser Franz , Kwasniewska Sylwia , Henchoz Pierre-David , van der Zypen Eugen , England Ceri 
Published: April 2021

ABSTRACT
The effectiveness of cw-Nd:YAG and diode laser light in performing transscleral chorioretinal coagulation is demonstrated in cadaver porcine eyes using a new contact probe that facilitates irradiation of these layers. Both radiation sources also may be viable alternatives to argon laser light in effecting chorioretinal and cycloendocoagulation.
Automated Perimetric Changes Following Panretinal Photocoagulation in Diabetic Retinopathy
Authors: Khosla P K , Gupta Vivek , Tewari H K , Kumar Atul 
Published: April 2021

ABSTRACT
Sixty eyes - 30 with severe nonproliferative diabetic retinopathy (NPDR) and 30 with proliferative diabetic retinopathy (PDR) - underwent argon laser panretinal photocoagulation (PRP). Static perimetry (Humphrey automated visual field analyzer 630, Threshold Prog Central 30-1 and Peri 30/60-1) was done 1 day before and 6 weeks after the initial laser treatment. One day before treatment, the fields of the NPDR and PDR eyes differed mainly in the central field affection: the PDR eyes had more localized areas of markedly decreased retinal sensitivity and, therefore, a higher initial mean deviation value and higher corrected pattern standard deviation values. However, peripheral retinal sensitivity was equally depressed in the NPDR and PDR eyes. Six weeks after treatment, central retinal sensitivity had significantly improved in all of the eyes, although more so in the eyes with severe NPDR. This study suggests that static-perimetry-guided PRP is an effective treatment for diabetic retinopathy, especially severe NPDR.
Posttrabeculectomy Anterior Subcapsular Cataract Formation Induced by Anterior Chamber Air
Authors: Asamoto Ayako , Yablonski Michael E 
Published: April 2021

ABSTRACT
We retrospectively examined the effect of air, as contrasted with balanced salt solution (BSS), sodium hyaluronate, or no substance at all, used to reform the anterior chamber at the end of trabeculectomy on subsequent cataract formation in 141 consecutive patients (173 phakic eyes). The minimum follow up was 120 days. The use of air increased the incidence of anterior subcapsular cataract formation significantly. Also, the eyes that had a large air bubble on postoperative day 1 had a higher incidence of anterior subcapsular cataract than the eyes with less air on that day. We suggest that the toxicity to the lens of the oxygen in the air increased the incidence of anterior subcapsular cataract in the eyes in which air was used. We recommend that BSS or sodium hyaluronate be used instead of air to reform the anterior chamber following trabeculectomy.
Surgical Correction of Upper Eyelid Retraction
Authors: Liu Don 
Published: April 2021

ABSTRACT
Over the last 7 years, I have used a "central aponeurosis disinsertion" technique to correct dysthyroid upper eyelid retraction in nine patients. Consistent and predictable results were achieved and maintained over follow-up periods ranging from 18 to 72 months. The technique is simple and effective, and does not involve extensive dissection or the use of a spacer.
Combined Extracapsular Cataract Extraction, Posterior Chamber Intraocular Lens Implantation, and Pars Plana Vitrectomy
Authors: Foster Robert E , Lowder Careen Y , Meisler David M , Zakov Z Nicholas , Meyers Sanford M , Ambler John S 
Published: April 2021

ABSTRACT
The surgical management of coexisting cataract and vitreoretinal disease has been controversial, particularly for eyes with a history of proliferative diabetic retinopathy (PDR) or chronic uveitis. We retrospectively studied the results of combined extracapsular cataract extraction (ECCE), posterior chamber intraocular lens (PC-IOL) implantation, and pars plana vitrectomy in 20 eyes of 16 patients. The indications for combined vitrectomy included dense, nonclearing vitreous hemorrhage attributed to PDR in 10 eyes, age-related macular degeneration in 2, and trauma in 1. The remaining 7 eyes had pars plana vitrectomy to remove inflammatory vitreous cell and debris associated with chronic uveitis. Follow up ranged from 4 to 32 months (average, 17.4 months). Visual acuity improved in 19 eyes (95%)- to 20/100 or better in 12 (60%). The improvement ranged from 1 to 13 Snellen lines (average, 4.9 lines). Postoperative visual acuity improvement averaged 7.5 Snellen lines for eyes with chronic uveitis, 7.0 lines for those with age-related macular degeneration, and 3.3 lines for those with a history of PDR. Postoperative visual acuity was less than 20/100 in 8 eyes (40%). In most cases, these latter results were attributed to macular changes associated with the underlying ocular disease. Our results confirm previous studies that have shown that combined ECCE/PC-IOL implantation and pars plana vitrectomy is a well-tolerated surgical procedure for diabetics, which can provide clear anterior and posterior segment media. In addition, our results suggest that this combined procedure can be useful in restoring vision in certain eyes with uveitis in the short-term postoperative period.
A New Technique for Combined Cataract/Glaucoma Procedures in Patients on Chronic Miotics
Authors: Whitsett Jeffrey C , Stewart Robert H 
Published: April 2021

ABSTRACT
We describe a combined cataract/glaucoma procedure for patients on chronic miotics that includes smallincision phacoemulsrfication to provide increased predictability of visual outcome and early visual rehabilitation, and an inferior pupilloplasty to facilitate intraoperative visualization. To date, 42 procedures have been performed with excellent results. Complications, although minimal, have included iridolenticular/ iridocapsular adhesions, diplopia, rupture of 10-0 polypropylene sutures, peripheral anterior synechia, hyphema, and fibrinoid aqueous.
Nd:YAG "Sweeping"-An Indirect Technique for Clearing Intraocular Lens Deposits
Authors: Vajpayee Rasik B , Angra Surendra K , Honavar Santosh G , Kumar Harsh 
Published: April 2021

ABSTRACT
Corticosteroid-resistant deposits on the anterior surface of intraocular lenses (1OLs) in 11 patients who had complained of poor vision were "swept" with a Neodymium:YAG laser beam. As contrasted with previous "direct hit" methods, our method is indirect, using a low-power, defocused beam to generate an acoustic shock-wave, which then sweeps the lens surface clear of deposits. The deposits were cleared in all 11 patients, with no damage to the IOL or any other postlaser complications. Improvement in visual acuity ranged from 1 to 3 lines, and all the patients reported alleviation of symptoms.
Focal and Diffuse Visual Field Defects: Their Relationship to Intraocular Pressure
Authors: Samuelson Thomas W , Spaeth George L 
Published: April 2021

ABSTRACT
The view that visual field loss in "low-tension" glaucoma (LTG) is more focal than in ordinary or "high-tension" glaucoma (HTG) is controversial. The basis of the controversy may be the inappropriate presupposition that an arbitrary intraocular pressure (IOP) level effectively differentiates these entities. We attempted to determine whether meaningful differences exist between glaucoma patients classified on the basis of pattern of visual field loss rather than IOR One hundred consecutive glaucomatous visual fields were classified as focal or diffuse by two independent observers masked to all other clinical information. Several clinical parameters were then evaluated, comparing patients with focal visual field loss, with those with diffuse loss. Maximal pretreatment IOP was significantly lower among the patients with focal visual field loss than it was among those with diffuse loss (21.5 mm Hg ± 5.7 vs 25.9 mm Hg ± 4.7; P < .01). There was no difference between the two groups in terms of age, blood pressure, visual acuity, or color vision. We conclude that focal glaucomatous visual field loss occurs at a lower IOP than diffuse loss and, as such, may be a marker by which to identify patients whose optic nerves are abnormally susceptible to glaucomatous injury.
Transscleral Neodymium:YAG Laser Cyclophotocoagulation for End-Stage Glaucoma, Refractory Glaucoma, and Painful Blind Eyes
Authors: Al-Ghamdi Saleh , Al-Obeidan Saleh , Tomey Karim F , Al-Jadaan Ibrahim 
Published: April 2021

ABSTRACT
We used transscleral NeodymiunrYAG laser cyclophotocoagulation (TSYLCC) to treat 47 patients (47 eyes! with end-stage, refractory, or absolute glaucoma. The mean pretreatment intraocular pressure (IOP), 40.5 ± 10.8 mm Hg, decreased a mean of 13 ± 8 months following treatment to 15.6 ± 10.6 mm Hg, a statistically significant change (P < .05). Our overall rate of success (final IOP « 25 mm Hg, with or without medications) was 79% (37 eyes). Early complications included pain (11 eyes) and inflammation (13 eyes); late complications included hypotony (7 eyes), high IOP (5 eyes), and decreased visual acuity (4 eyes). TSYLCC seems to be a safe, effective, and convenient outpatient procedure.
Use of Perfluoroperhydrophenanthrene in the Management of Posteriorly Dislocated Crystalline and Intraocular Lenses
Authors: Greve Mark D J , Peyman Gholam A , Mehta Nalin J , Millsap C Mark 
Published: April 2021

ABSTRACT
We describe a series of 28 patients in whom a posteriorly dislocated crystalline or intraocular lens was successfully removed with the intraoperative use of perfluoroperhydrophenanthrene (Vitreon), a heavy liquid perfluorocarbon. The Vitreon was used to float the lens into the midvitreous cavity, thereby avoiding hazardous micromanipulation with intraocular instruments in the macular area. In addition, the Vitreon served to protect the posterior retina by keeping the posteriorly dislocated lens fragments from falling backward onto the posterior pole as the lens was being removed from the eye. Postoperative visual acuity improved in 73% of the patients, remained the same in 15%, and worsened in 12%.
Silicone Oil Tamponade for Retinal Detachment and Delayed Treatment of Retinal Tears
Authors: Zauberman Hanan , Hemo Itzhak 
Published: April 2021

ABSTRACT
Four patients underwent a vitrectomy procedure for retinal detachment associated with anterior and posterior proliferative vitreoretinopathy (D-1 type). In each patient, an internal tamponade was achieved with 1000-centistoke silicone oil. Preretinal and/or subretinal hemorrhage that was difficult to remove during surgery, as well as remnants of subretinal fluid, prevented complete intraoperative treatment of the retinal tears or the retinotomy with endolaser photocoagulation. The silicone oil tamponade kept the retina flat until laser treatment was applied to the retinal tears several weeks later, when the retinal blood and subretinal fluid had reabsorbed.
When circumstances make achieving intraoperative laser marks difficult, silicone oil tamponade appears to be superior to a long-lasting gas tamponade. It provides a more permanent tamponade than gas and excellent visualization of the fundus several weeks after surgery, at which time laser marks can be completed.
Migration of Solid Silicone Encircling Element Through Four Rectus Muscles
Authors: Maguire Albert M , Zarbin Marco A , Eliott Dean 
Published: April 2021

ABSTRACT
Anterior migration of an encircling element through a rectus muscle is an unusual complication of scierai buckling surgery. We describe two patients with migration of a solid silicone encircling element through the insertions of all four rectus muscles after retinal detachment surgery. Buckle migration was associated with elevated intraocular pressure and glaucomatous optic atrophy. Rectus muscle function was preserved in both patients. Despite transsection of the anterior ciliary blood supply, anterior segment ischemia did not develop.
Pseudo-Brown's Syndrome as a Complication of Glaucoma Drainage Implant Surgery
Authors: Prata João Antonio , Minckler Donald S , Green Ronald L 
Published: April 2021

ABSTRACT
Two cases of pseudo-Brown's syndrome occurring after superior nasal implantation of glaucoma filtering devices are described. We hypothesize that this restriction in ocular motitity was due to the mechanical effects of large filtering blebs or increased inflammation and scar formation in the superior nasal quadrant. Serial ultrasound examinations of our patients demonstrated development of a large bleb, coincidental with the disturbance in motility. Because of the risk of strabismus, we no longer recommend placing large implant devices in the superior nasal quadrant in eyes that have good vision.
The Necessity of Long-Term Follow Up After Surgery for Basal Cell Carcinomas of the Eyelid
Authors: Steinkogler Franz Josef , Scholda C D 
Published: April 2021

ABSTRACT
Both diagnostic and therapeutic problems remain in the treatment of basal cell carcinomas of the eyelid. Incorrect initial diagnosis and resulting inadequate treatment can lead to the loss of the bulbus. Inadequate follow up may result in failure to detect a recurrent tumor. We retrospectively studied 226 patients with basal cell carcinoma of the eyelid who had surgery some time between 1980 and 1989. In 179 patients, a primary lid tumor was removed; the recurrence rate for these patients was 6.1%. Forty-seven patients had surgery for secondary eyelid basaliomas; the recurrence rate for these patients was 14.8%. These recurrence rates correlated clearly with the horizontal extent and depth of the tumor, and with the appearance of the sclerodermiform type. The fact that recurrences were found after 3 years demonstrates the importance of long-term follow up in these patients, especially in those with secondary tumors and tumors of exceptional height.