bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANÁLISE SISTÊMICA TEMPORAL DE DUAS COMUNIDADES EM ASSENTAMENTO RURAL NO ESTADO DO PARÁ, AMAZÔNIA BRASILEIRA
Authors: Silva Higor Almeida da , Gama João Ricardo Vasconcellos , Monteiro Raimunda Nonata 
Published: November 2021

O objetivo deste estudo foi analisar o potencial de uso dos recursos florestais madeireiros e não madeireiros e a produção agropecuária familiar das comunidades rurais São Mateus e Santo AntônioÂ dos anos de 2008 e 2018. Foram avaliados os aspectos socioeconômicos e ambientais por meio de inventários florestais e com base em entrevistas semiestruturadas e pesquisas de campo. No inventário florestal das duas comunidades rurais foram encontradas 322 espécies, distribuí­das em 92 famí­lias botânicas, sendo a Famí­lia Fabaceae a mais representativa com 125 espécies. Apesar dos resultados revelarem um estoque de espécies com potencial madeireiro e não madeireiro e melhorias socioeconômicas, a maioria dos agricultores familiares (97%) apresentou alto grau de insatisfação em relação à falta de assistência técnica pública a fim de planejar suas produções através da associação de sistemas agroflorestais diversificados. Este estudo cria um modelo participativo capaz de contribuir com as polí­ticas públicas voltadas para subsidiar o potencial de uso dos recursos florestais em assentamentos rurais na Amazônia, bem como promover a formação de programas de incentivo ao desenvolvimento sustentável, considerando o mercado atual e agregando valor aos produtos.
UMA ANÁLISE ESPACIAL DO OESTE DO PARANÁ: CENÁRIOS PARA O DESENVOLVIMENTO REGIONAL
Authors: Cima Elizabeth Giron , Uribe-Opazo Miguel Angel , Rocha Junior Weimar Freire da , Fragoso Rui Manuel de Souza 
Published: November 2021

Este estudo analisa se existe uma relação direta entre municí­pios limí­trofes do oeste do estado Paraná, Brasil, e o seu desenvolvimento regional. Deste modo, analisou-se a autocorrelação espacial do efetivo da produção pecuária (quantidade de bovino, suí­no, aves e produção leiteira) dos anos 2011 a 2017, do valor bruto da produção agropecuária (VBPA), do valor adicional fiscal per capita (VAF) dos anos 2013 a 2015 e a correlação espacial bivariada do valor adicional fiscal per capita em relação ao efetivo da produção pecuária dos anos 2013 a 2017. O referencial teórico se embasou na avaliação espacial de desempenho com base nas técnicas de í­ndice de autocorrelação global de Moran, local de Moran e correlação bivariado de Moran. Os resultados permitem identificar regiõesÂ com baixo e elevado efetivo de produção pecuária, valor bruto da produção agropecuária e í­ndice de desenvolvimento humano por municí­pio (IDHPM). Houve maior autocorrelação espacial positiva para a produção de suí­nos, produção de leite, seguida do valor fiscal adicional per capita. Para o indice de desenvolvimento humano municipal, foram encontradas autocorrelações espaciais significativas. O valor adicional fiscal per capita apresentou semelhança entre as regiões estudadas. Ao avaliar a correlação espacial bivariada entre o valor adicional fiscal per capita (VAF) em relação ao efetivo da produção pecuária, observou-se a presença de correlação espacial positiva para a produção de suí­nos, aves e leite. Já para a produção de bovinos, o resultado apresentou correlação espacial negativa significativa.
The Translation of the Sibylla Tiburtina into Middle Welsh
Authors: van Seventer Nely 
Published: November 2021

The Sibylla Tiburtina is a medieval prophetic text with roots in Late Antiquity. It tells the story of the wise Sybil, who is summoned to the court of the Roman emperor when a hundred of his senators dream the same dream during the same night. Her explanation of this dream is a lengthy prophecy about future kings and their qualities and faults, as well as about the natural disasters and wars the future will bring. The whole culminates in a prophecy about the signs of the Day of Judgment.
The text has a long and complicated history of transmission. Originally written in Byzantine Greek, it has undergone considerable changes since being translated into Latin around the turn of the first millennium. Of this Latin text we have an edition with variants published by Ernst Sackur (1898). More recently, Anke Holdenried has worked extensively on the various versions of the Latin Sybil, and the differences between them, notably in her book The Sybil and her Scribes (Holdenried 2006). The first extant vernacular translation is in Norman French and dates from the twelfth century. There are two Middle Welsh versions of this text, one in Peniarth 14, the other in the Red Book of Hergest [RB] and the White Book of Rhydderch [WB]. In this paper, the latter will be discussed. There are only slight variations between these two versions, and I base my text on RB as edited recently on the Welsh Prose 1300–1425 project (Luft et al. 2013), with a few variant readings from WB in the same corpus. The Latin source of this translation is unknown, but must, as Marged Haycock has noted (Haycock 2005: 123), have been close to Sackur’s text. In my research I am interested in the translation process of the text from Latin into Middle Welsh, and in this paper I discuss some of the general tendencies of the Welsh translator of Sibli Ddoet ‘the wise Sybil’.
Use of MeNTS, Frailty and Symptom Scales for selecting surgical patients during the SARS-CoV-2 pandemic: A retrospective study
Authors: Tafur Betancourt Luis Alberto , Rosero Cundar Adriana Sofía , Remolina Granados Sergio Andrés , Arévalo Marcela , Millán G. María del Mar , Lema Flórez Eduardo , Zorrilla Vacca Andrés , Ruiz Holguín Víctor Hernán , Ceballos Catalina , Quintero Soto Jaime 
Published: November 2021

Introduction: The SARS-CoV-2 pandemic has led to the cancellation of non-emergent surgeries in order to optimize the use of resources. Once the elective medical services are restored, a technical and ethical strategy becomes critical to select candidate patients for elective surgery.
Objective: To describe the results from the implementation of MeNTS (Medically Necessary Time-sensitive Procedures), FI-CGA, and survey on COVID-19 symptoms Scales, as methods for the selection of patients who were candidates for elective surgery during the SARS-CoV-2 pandemic, in a third level institution in Cali, Colombia.
Methodology: The databases of the results on the administration of MeNTS, frailty index (FI-CGA) and COVID 19 symptoms scales in patients who were candidates for elective surgery in a third level clinic in Cali city, between March 1st and August 31st, 2020 were reviewed.
Results: A total of 1,044 patients were included, of which 647 (62.0 %) were females, with a mean age of 52 years (interquartile range [IQR] 38-62). 98 % of the patients were asymptomatic, the overall median score for MeNTS was 48 (IQR 44-52) and the average for FI-CGA was 0.0 (standard deviation 0.1).
Conclusions: MeNTS, FI-CGA and the Symptoms Survey are easily accessible scales amidst the pandemic and are helpful to select patients with intermediate and low risk of perioperative morbidity in elective surgery during the SARS-CoV-2 pandemic. Further studies are required to confirm these findings and to clarify the potential of these tools in the selection of patients that meet the criteria to be identified as high risk.
Revisiting the Balanced Book Hypothesis – Bettor Preferences and Results in the NFL
Authors: Paul Rodney , Weinbach Andrew 
Published: November 2021

Data on betting percentages, both in terms of number of bets and actual money wagered, is still difficult to find. Sports Action Network, in their premium access service, does provide this data in terms of both number of bets and money bet. For the2020 NFL season, it was found that the balanced book could be rejected as bettors were shown to prefer road favorites, big favorites, and the over at the highest totals. Allowing this imbalance in the sides market appeared profitable for the book as the underdog won more often than implied by efficiency, while totals were evenly split.
Tržní riziko: zbytný předpoklad kvalifikace (investičního) fondu?
Authors: Weiss Lukáš 
Published: November 2021

The current public regulation of investment funds affects a wide range of contractual or corporate investment plans. If the investment plan falls under this regulation, it can be implemented only with the appropriate permit (or registration) under the supervision of supervisory authorities. Any misconduct is strictly sanctioned. This paper aims to answer the key question of whether one of the necessary material features or assumptions of the investment fund is that the investor’s investment is exposed to market risk arising from the acquisition, holding, or sale of assets in this fund. Decision-making practice has shown in the past that this material feature of the investment fund can be interpreted differently, which has had and have to have an impact on the predictability of the legal environment, legal certainty for capital market participants, and the capital market as a whole.
One Hundred Years of the Pathology Medical Student Fellowship
Authors: Hammer Phoebe , Ireland Karen , Houghton Donald C. , Jaggers Alexis , Coleman Anya , Snir Olivia L. , Troxell Megan L. , Andeen Nicole K. 
Published: November 2021

Context.—
The Pathology Medical Student Fellowship (PSF) is a unique, year-long immersive educational experience. Review of institutional archives describes a medical student “Fellowship in Pathology” founded in 1919.

Objective.—
To characterize the impacts of this 100-year-old program.

Design.—
We determined the subsequent medical specialty of each PSF graduate in our department and surveyed those with available contact information.

Results.—
Of 145 pathology student fellows graduating between 1924 and 2020, a total of 50 (34.4%) matched into pathology; medical, surgical, and radiology subspecialties were also well-represented career choices. Between 2001 and 2020, of 36 students who matched into pathology from our institution, 19 (52.8%) had completed the fellowship. Survey respondents (n = 42) indicated that before the PSF, 11 of 42 students (26.2 %) were undecided in their specialty, with only 6 (14.3%) identifying pathology as their primary field of interest. Of survey respondents who had completed training, 26 (61.9%) practice in academic settings. Nonpathology physicians reported frequent utilization of skills gained during the PSF year, with 5 of 23 (21.7%) responding “daily,” and 9 (39.1%) responding “weekly.” The most useful skills included knowledge of pathophysiology of disease and anatomy, improved communication with multidisciplinary teams, and/or interpretation of pathology results (each selected by 17 to 20 students, 73.9%–87.0%). Free-text responses on impacts of the PSF described enhanced knowledge of disease pathobiology and diagnostic complexity and increased confidence and autonomy.

Conclusions.—
We describe the program structure, educational benefits, graduate specialty choices, and career impacts of 100 years of the PSF at our institution. Although undecided before pathology exposure, many PSF graduates subsequently enter pathology careers. Regardless of specialty choice, PSF graduates have a high rate of subsequently pursuing academic medical careers.
Tra virtuosismo e truffa: l’arte del falsario
Authors: Cerboni Baiardi Anna 
Published: November 2021

The history of artistic forgery boasts rather old origins and numerous facets. On this occasion, some emblematic cases between the Cinquecento and the present day (from the Sleeping Cupid of Michelangelo to the ‘Modiglianis’ that hit the headlines only some decades ago) will be taken into account, along with the activity of some great forgers who lived between the nineteenth and twentieth centuries. Gifted with notable technical ability and virtuosic stylistic “mobility”, some of these realized true masterpieces in meeting the requests of a growing market of Italian and foreign collectors. Above all others, one should mention the names of Egisto Rossi (1824-1899), falsifier of Old Masters’ drawings, and that of Icilio Federico Joni (nicknamed Paicap; 1866-1946), who specialized in counterfeiting fondo oro paintings by the Sienese School and was the leader of the city’s forgers.
Dirk ex Machina: Douglas Adams’ Saga and Holistic Detection as Religious Satire
Authors: Gianotti Emilio 
Published: November 2021

Douglas Adams, in his Dirk Gently series, presents his protagonist as a “holistic detective”. Following in the tradition of Sherlock Holmes, the detective bases his claims on scientific evidence and always succeeds in his enquiries. However, the mechanics of his comically random detecting behavior clash with the conclusiveness of the plot, casting doubt on the control of the protagonist over his method. A study of these mechanics as inherently computer-like elicits an interplay between the openness of a holistic postmodern pastiche and the reassuring closure granted by the appeal to science. An analysis of these core concepts, and of the influence of the New Atheist movement on the author, leads to an underlining of the satiric elements of the series. As satires of religion, these novels attack false systems of belief in favor of an enjoyment of uncertainty that waits for the answers of science.
Screening for Drought Tolerance through Root Morphology and Yield Characters of Groundnut (Arachis hypogaea L.) Genotypes
Authors: Kumar K. Manoj , Vincent S. , Mothilal A. , Raveendran M. , Anandham R. , Prasad V. Babu Rajendra , Suneel D. 
Published: November 2021

Drought affects the rainfed groundnut (Arachis hypogaea L.) at different phases of development and it is the serious threats on groundnut productivity causing losses than any other abiotic factor under rainfed agriculture. In the world's semiarid regions, groundnut accounts for 90% of worldwide production. Drought mainly affects the pace and pattern of nutrient and water intake from the soil, affecting the architecture of the groundnut root system. Plant selections with desirable root trait have been a major focus in developing drought resistant Groundnut cultivars. In 2019, 60 groundnut genotypes were cultivated in root block design with two different soil water treatments, as well as in the field during the year under same circumstances. The purpose of this study was to see how different groundnut cultivars fared in terms of yield, yield contributing features, root characters, and their relationships with drought tolerance. Drought resistant genotypes had thicker roots, larger roots, and a deeper root system than susceptible genotypes. Recent series in groundnut genotypes of 60 numbers were sown during kharif 2019 (july-september) under rainfed condition (It includes life irrigation and rainfall received during cropping season). Groundnut genotypes were semi spreading with the duration of 110-120 days. Observation on root morphological character viz., roots length, root volume after 20 days of stress imposition of the crop and yield parameters were observed at the harvest. Among the 60 genotypes, 20 genotypes (VG 17008, VG 17046, VG 18005, VG 18102, VG 18077, VG 19572, VG 19709, VG 18111, VG19561, VG19576, VG 19620, VG 19681, VG 19688 etc.,) similarly, yield character were observed for 60 genotypes and all the genotypes given above recorded higher value in Total number of pods per plant, Number of double seeded pods per plant, Pod yield per plant, Harvest index and Total dry matter production. The methods used in this study identified correlation between yield character and root characters. Groundnut genotypes by assessing yield metrics and their relationship with root trait. These findings lay the groundwork for future study aimed at deciphering the molecular pathways underpinning Groundnut drought resistance.
A Clinicopathological Study of Malignant Tumors of the Uterine Corpus in a Tertiary Care Center
Authors: Binu Irene Sara , Diwagar K. Nithin , Sekhar Ganthimathy 
Published: November 2021

Aim: To study the clinicopathological spectrum of malignant tumors of the uterine corpus in a tertiary care center and classify it according to the latest WHO classification.
Methods: A 2 year study was conducted on 22 diagnosed cases of malignant tumors of uterine corpus. Retrospectively clinical and histopathological details were collected and analyzed.
Results: In our study majority (40.90%, 9 of 22) cases belong to the age group of 51-60 years. Abnormal uterine bleeding was the most common clinical presentation. A large share (81.81%) of the tumours was of epithelial origin, followed by mixed and mesenchymal tumors. Nearly 94% of the epithelial tumours were Endometrioid Adenocarcinomas. Majority of the cases were at pT1a stage (42.1%) at the time of diagnosis, followed by pT1b stage (31.57%). Very few cases (21%) presented with nodal metastasis. All the cases with nodal metastasis showed Lymphovascular invasion in the tumor proper and were usually high grade tumors.
Conclusion: The prognosis of the patients with malignant tumors of uterine corpus depends on stage, grade, myometrial invasion, tumor size, lymphovascular invasion etc. Clinical findings in these tumors are not specific, so Histopathological examination plays a vital role in diagnosing and assessing the prognosis of these tumors. Classifying these tumors according to the recently proposed molecular classification will aid in patient specific targeted therapy.
Preparation and Characterization of Solid Lipid Nanoparticles of Cinnacalcet HCl
Authors: Routray Sudhanshu Bhusan , Patra Ch. Niranjan 
Published: November 2021

Objective: The objective of the present research is to formulate solid lipid nanoparticles of cinnacalcet HCl to improve its oral bioavailability.
Methods: Cinnacalcet hydrochloride exhibits poor oral bioavailability of 20 to 25 % because of low aqueous solubility and first pass metabolism. The formulations were optimised using Box-Behnken Design. Solid lipid nanoparticles formulation was prepared using hot homogenization and ultra sonication method.
Results and Discussion: Precirol ATO 05, Soya lecithin and poloxamer 407 were selected as lipid, surfactant and co-surfactant respectively. For optimistaion the desirable goal was fixed for various responses entrapment efficiency, particle size and (time taken for diffusion of 85% drug) T85%. The optimized single dose of solid lipid nanoparticle obtained using box behnken design consisting of 30 mg of cinnacalcet HCl, 200 mg of precirol ATO 05, 250 mg of soya lecithin and 0.2% w/v of poloxamer. 407. The pharmacokinetic study revealed that optimized formulation was found to increase the oral bioavailability nearly 3 times compared to aqueous suspension of pure drug.
Conclusion: Thus optimized solid lipid nanoparticle explicated the potential of lipid-based nanoparticles as a potential carrier in improving the oral delivery.
Updates in Diagnosis and Management of Croup
Authors: Sheikh Mohammed Hussen , M. Albalawi Haya Jamal , S. Albalawi Yazeed Ali , R. Alotaibi Mohammed Abdulhafith , M. Alsharef Sultan Makki , A. Alshehri Ali Abdulrahman , A. Albalawi Ahmed Saad , A. Albalawi Abdulaziz Saed , H. Alamri Mohammed Abdulwahed , Mohammed AlTurki Abdulrahman , Q. Al-Ruwaili Sultan Suliman , Alqrafi Mohammad , Alenzi Sarah Awad Muhammad , D. Alharbi Rahaf Saad , H. Alomrani Heba Homoud 
Published: November 2021

Croup is a common respiratory disease that affects 3% of children aged six months to three years. It represents 7% of annual hospital admissions for fever and/or acute respiratory disease in children under the age of five. Boys are more susceptible than girls to the condition, with an overall male/female predominance of 1.4/1. Viruses are detected in up to 80% of patients with croup with identifiable pathogens. The onset of symptoms is usually sudden and usually occurs at night: stridor, hoarse voice and respiratory distress are often seen due to upper airway obstruction. Croup is a clinical diagnosis, children with an uncertain diagnosis, anterior and lateral soft-tissue neck radiographs may be useful to support an alternative diagnosis. Management includes: general care, humidified air, heliox, corticosteroids, and epinephrine, Objective: This study aimed to discuss croup in terms of its etiology, pathogenesis, clinical features, diagnosis, assessment, and finally management.
Development and Validation of Ultra Performance Liquid Chromatographic Method Simultaneous Estimation of Aspirin and Ticlopidine Hydrochloride in Pharmaceutical Formulation
Authors: Wankhede B. , Jangam S. S. , Nimje H. M. , Khobragade D. S. , Parkhe P. D. 
Published: November 2021

Objective: The combined dose tablet formulation containing aspirin and ticlopidine hydrochloride is used to reduce the formation of harmful blood clots in blood vessels which helps in preventing a heart attack or stroke in people with heart disease. The objective of the present work was to develop an accurate, precise, economical and less time consuming UPLC method and subsequently validate the method as per ICH guidelines, for routine quality control of combined dose tablet formulation containing above mentioned drug.
Methods: The present work describes development and validation of ultra performance liquid chromatographic method for simultaneous quantitation of aspirin and ticlopidine hydrochloride in tablets. The chromatographic separation was carried out using Supelcosil LC-18 (3.3 cm × 4.6 mm × 3 µm) column using mixture of Potassium Phosphate buffer (0.01M) and Acetonitrile (20:80 v/v) as mobile phase with a flow rate of 0.6 ml per minute, total run time was 3 minutes. The detection and quantitation of chromatographic peaks was carried out at 230 nm.
Results: The retention time for aspirin (ASP) and ticlopidine hydrochloride (TPH) was 0.529 minutes and 1.530 minutes, respectively. The linearity of detector response was observed in the concentration range of 20 – 60 µg/ml and 50-150 µg/ml for ASP and TPH, respectively. The LOD and LOQ for ASP and TPH was found to be 0.399 & 1.209 and 3.385 & 10.260, respectively. The accuracy of the method was found in the range of 99.92 – 100.58 % and 98.91 – 100.52 for ASP and TPH, respectively. The relative standard deviation for intra-day and inter-day precision studies was below 2 % indicating that the method is precise. The robustness of the proposed method was evaluated by varying the chromatographic parameters and the effect of these changes on retention time and tailing factor was studied. The % RSD for retention time and tailing factor was below 2 % indicating that the method is robust. The forced degradation studies were carried out to evaluate the specificity of the method. As the method was able to quantitate ASP and TPH selectively in presence of degradation products, the method was found to be specific. As the results of validation studies were within standard limits, the method was successfully applied for simultaneous estimation of ASP and TPH in marketed tablet formulation.
Conclusion: The method has distinct advantages over reported UV and HPLC methods and hence the developed UPLC method can be used for routine quality control of Aspirin and Ticlopidine hydrochloride combined tablet formulation.