bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical value of neuronavigation combined with a fluorescent staining technique during microsurgery for treating supratentorial glioma
Authors: Yang Fugang , Xu Chengshi , Ma Chao , Zhao Yuhang , Li Zhiqiang 
Published: March 2021

Background and Aim:
Many studies have demonstrated the value of neuronavigation guided by fluorescence staining for treating glioma patients. Here, we compared the rate of overall survival (OS) and the extent of tumor resection among patients who underwent surgery with neuronavigation and fluorescence versus conventional techniques.

Materials and Methods:
In this case-control observational study, data from 162 patients with supratentorial glioma who underwent surgery from January 2016 to November 2017 were retrospectively analyzed, including a neuronavigation and fluorescence treatment group (combined group, n = 53) and a conventional microsurgery group (control group, n = 109). The extent of tumor resection, World Health Organization (WHO) pathological grade, eloquent areas involved, tumor diameter, preoperative Karnofsky Performance Status score, underlying diseases, chemotherapy, hospitalization days, length of operation, intraoperative blood loss, and postoperative molecular pathological indictors were recorded. OS rates were compared using the Cox proportional hazards regression model. The study was approved by the Ethics Committee of Zhongnan Hospital of Wuhan University (approval No. 2019048).

Results:
The total resection rate was 60.4% in the combined group and 27.5% in the control group. Multivariate logistic regression analysis revealed that involvement of eloquent areas (odds ratio [OR] = 0.455, 95% confidence interval [CI]: 0.214–0.966, P = 0.040) and the use of the combined technique (OR = 3.634, 95% CI: 1.758–7.510, P < 0.001) were independent prognostic factors affecting total glioma resection. Eloquent areas were implicated in 79 patients. Multiple logistic regression analysis revealed that the combined technique (OR = 6.041, 95% CI: 1.705–21.403, P = 0.005) was an independent prognostic factor affecting total resection. The average follow-up period was 16.4 months. Cox regression analysis revealed that the WHO tumor grade (hazard ratio [HR] = 4.782, 95% CI: 1.620-14.119, P = 0.005), chemotherapy regimen (HR = 0.324, 95% CI: 0.181–0.579, P < 0.001), IDH mutation (HR = 0.366, 95% CI: 0.154–0.870, P = 0.023), and total resection (HR = 0.458, 95% CI: 0.248–0.846, P = 0.013) were independent factors affecting the prognosis of glioma patients.

Conclusions:
The use of neuronavigation with fluorescent staining appears to improve the tumor resection range and the OS rate, which is an independent factor affecting the degree of resection of supratentorial glioma. The WHO tumor grade, chemotherapy regimen, IDH mutation, and total resection were independent factors affecting the prognosis of glioma patients.
In-silico investigation of active component
Authors: Arunachalam Preethi , Ramadoss Ramya , James Amritha , Jayan Lekshmy , Vinoth Vasanthi , Divya Bose 
Published: March 2021

Background:
Xerostomia is a common condition which affects majority of the people due to its multifarious etiologies. Although several treatment modalities are under practice, natural herbs show a great deal of beneficial effects recently. Saliva contains a considerable amount of proteins, among which the enzyme salivary α-amylase forms the major bulk. Acacia
catechu is habitually known as Katha or Karangali, and the preparations are made from the heartwood or the leaves of this plant and have been used for decades and also as a thirst quencher. The relationship between the use of this decoction and saliva secretion has been a debate among researchers. Although there are no comprehensive validations behind the theory between amylase activity and A. catechu, virtual screening techniques such as docking could help to throw light on this theory.

Aim:
This study aimed to evaluate the binding efficacy of active ingredient of A. catechu on salivary α-amylase using molecular docking approach.

Materials and Methods:
The active ingredients of A. catechu were identified using an extensive literature search. The chemical structure of the identified ligand (epicatechin gallate) and the target protein (salivary alpha-amylase) was obtained using PubChem and molecular docking was analyzed using SYBYL2.0®.

Results:
Epicatechin gallate showed the highest binding affinity for human salivary amylase when compared to the other ligand molecules.

Conclusion:
The current study thus elucidates that A. catechu can possibly be effective as a stimulatory agent for patients suffering from xerostomia.
Relative position of mandibular foramen in 4–9-year-old children
Authors: Chandran Sruthi , Peedikayil Faizal C , Chandru T. P. , Kottayi Soni , John Seena 
Published: March 2021

Introduction:
Most common nerve block used in children is the inferior alveolar nerve block (IANB) for anesthetizing mandibular teeth. Therefore, knowledge of the location of the mandibular foramen is necessary for a successful IANB anesthesia.

Aim:
The study aimed to correlate the position of mandibular foramen in relation to the mandibular occlusal plane and the deepest point of the coronoid notch as a clinical guide for IANB injection in 4–9-year-old children.

Materials and Methods:
One-hundred orthopantamographs were analyzed and divided into two groups; Group 1 (4–6 years) and Group 2 (7–9 years). The orthopantamographs were traced on the acetate paper using a radiograph viewer and measurements were taken from mandibular lingula (ML) to the occlusal plane and to the deepest point of the coronoid notch.

Results:
Statistical analysis of the data revealed that there was a significant difference in mean distance between the two groups on both sides by measuring the position of ML to the mandibular occlusal plane and to the deepest point of the coronoid notch. Intergroup comparison of the distance from ML to the deepest point of the coronoid notch on the right and left sides shows a statistically significant difference (P < 0.001).

Conclusion:
There is a significant difference in both the distance and position of mandibular foramen in the considered age groups.
Case Report: A Fatal Case of West Nile Virus Meningoencephalomyelitis in a Woman with Systemic Lupus Erythematosus Initially Misdiagnosed as SARS-CoV-2 Infection
Authors: Schiuma Marco , Pezzati Laura , Ballone Elisabetta , Borghi Beatrice , Osio Maurizio , Mattavelli Daniele , Galimberti Laura , Corbellino Mario , Mileto Davide , Zanchetta Nadia , Antinori Spinello 
Published: March 2021

ABSTRACTWe present a fatal case of West Nile virus meningoencephalomyelitis initially misdiagnosed as COVID-19 in a 63-year-old Egyptian woman with a previous diagnosis of systemic lupus erythematosus. The patient’s medical history and immunosuppressive therapy, as well as the COVID-19 pandemic, substantially broadened the differential diagnosis of her encephalitis.
Analysis of the potential of contrailer transport (on the example of the Kaliningrad transport hub)
Authors: Rybin P. K. , Novikova I. D. , Moroz J. A. 
Published: March 2021

The subject of the research is the study of the potential of piggyback transportation on the basis of the multimodal terminal and warehouse infrastructure of the Kaliningrad railway. The relevance of the topic is determined by the intensification of international trade, which requires simplification of receiving and dispatching and transfer operations in a complex logistics system for the delivery of goods and the use of intermodal transport modules to speed up the listed operations, and, as a result, reduce the delivery time of goods. One of the types of intermodal transport modules is a piggyback, which can be transported by both rail and road transport, and processed at specialized cargo terminals. As a rule, piggyback terminals are located in large transport hubs with significant volumes of transit traffic. The conditions of the Kaliningrad transport hub are considered as the basis for the formation of a transport and logistics framework for the development of piggyback transportation.Methods used: analytical, design, evolutionary-functional, forecasting.With the help of forecasting and analysis methods, the potential of the market for piggyback transportation on the Kaliningrad railway has been investigated, taking into account statistical data over the past few years.The features of the Kaliningrad transport hub and the functioning of railway transport for servicing international transit using multimodal cargo delivery technologies are considered. The performance indicators of the Kaliningrad railway have been studied, and several alternative scenarios for the dynamics of transportation by means of contrailers have been predicted. A general assessment of the conditions of the Kaliningrad region for the prospective development of the volume of transportation of goods and cargo in foreign trade using piggyback.
Formation of corporate competencies of Russian Railways in the context of lifelong education
Authors: Goreva O. V. , Kutsenko S. M. 
Published: March 2021

The key results of the program of interaction between JSC “Russian Railways” and railway transport university complexes until 2025 include the following: approval of selection criteria and assessment procedures for candidates for targeted training from among applicants; assessment of competencies and tests of abilities according to the methods approved by JSC “Russian Railways” for all university graduates and students under contracts for targeted training of the company. To achieve these results, the task of designing a map of the development of Russian Railways corporate competencies at various levels of education is relevant.Using the methods of system analysis of Russian Railways regulatory documents and Federal state educational standards, this article presents a model of educational programs succession by education levels in order to design educational trajectories in accordance with the request for Russian Railways corporate competencies.The proposed model of developing Russian Railways corporate competencies in the context of lifelong learning will be useful for educational organizations in designing educational routes for students, forming criteria for competencies assessing at various education levels, adjusting the content of additional and basic educational programs in order to train highly qualified personnel for JSC “Russian Railways”.
HSCT FOR MYELODYSPLASTIC SYNDROMES (MDS)
Authors: Duarte Fernando Barroso , Barroso Karine Sampaio Nunes , Silva Roberto Luiz da , Gurgel Livia Andrade , Leitão João Paulo de Vasconcelos , Pitombeira Beatriz Stela Gomes de Souza , Soares Rodolfo Daniel de Almeida , De Pádua Leandro , Betarello Gustavo 
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
HSCT FOR PEDIATRIC DISEASES
Authors: Seber Adriana , Gomes Alessandra , Vieira Ana Karine , Rodrigues Ana Luiza Melo , Silva Ana Maria Marinho da , Zanette Antonella , Macedo Antonio Vaz de , Breviglieri Carla Nolasco Monteiro , Zanchetta Carla , Bonfim Carmem , Kuwahara Cilmara , Carvalho Cinthya Rocha , Castro Junior Cláudio Galvão de , Lelis Fernanda Lima , Netto Gabriele Zamperlini , Zamperlini Gustavo , Garcia Julia Lopes , Fernandes Juliana Folloni , Silva Karoline Helena Silva da , Fortunato Laila Rigolin , Gregianin Lauro José , Daudt Liane Esteves , Domingues Luciana , Darrigo Junior Luiz Guilherme , Matos Maria Gabriela , Lee Maria Lucia , Michalowski Mariana Bohns , Ikoma-Colturato Maura , Cypriano Monica , Borges Natália Maria Tavares Ferreira , Villela Neysimelia Costa , Soriano Paola , Ikeuti Patrícia Shimoda , Klinger Paulo Henrique dos Santos , Ribeiro Raul , Guimaraes Renata Fittipaldi , Tavares Rita Barbosa , Gouveia Roseane , Nichele Samantha , Franco Simone De Castro Resende , Ginani Valeria Cortez , Zecchin Victor Gottardello , Fernandes Virginio 
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
DONOR SELECTION: GENERAL ASPECTS
Authors: Pereira Simone Cunha Maradei , Souza Aline Miranda , Bouzas Luis Fernando , Oliveira Danielli Cristina Muniz de 
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
TRANSFUSIONAL SUPPORT IN HSCT
Authors: Kondo Andrea Tiemi , Prata Karen Lima , Souza Aline Miranda de , Lira Sanny Marcele da Costa , Ribeiro Andreza Alice Feitosa 
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
HSCT FOR HEMOGLOBINOPATHIES
Authors: Costa Thalita Cristina de Mello , Darrigo Junior Luiz Guilherme , Vieira Ana Karine , Albino Cintia Delbem , Barros George Maurício Navarro , Garcia Julia Lopes , Fortunato Laila Rigolin , Santos Flavia Leite Souza , De Santis Gil Cunha , Fonseca Guilherme , Guerino-Cunha Renato Luiz , Simões Belinda Pinto 
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
Strategi Sekolah Dasar Dalam Menumbuhkan Jiwa Kewirausahaan Peserta Didik
Authors: Maknuni Jauharil 
Published: March 2021

Era globalisasi adalah kebebasan berusaha yang didorong dengan persaingan bebas yang tidak terbatas, sehingga setiap manusia dituntut lebih kreatif dan inovatif dalam berbagai bidang. Oleh sebab itu, untuk menghadapi persaingan ini, sekolah khususnya sekolah dasar perlu membekali peserta didik menjadi jiwa wirausaha. Penelitian ini bertujuan untuk mengetahui strategi sekolah dalam menumbuhkan jiwa kewirausahaan peserta didik. metode penelitianya kualitatif deskriptif, dalam mengumpulkan data penelitian ini mengunakan wawancara, dokumentasi dan observasi, dari hasil penelitan maka ditemukan beberapa strategi sekolah dalam menumbuhkan jiwa kewirausahaan peserta didik, yang terutama pada saat perencanaan dirumuskan didalam rapat sekolah setiap awal tahun ajaran. Penyusunan program dihadiri oleh ketua yayasan, komite, guru, staff dan orangtua peserta didik. program-proram ialah niaga santri, entrepreneur zone, culinary corner, pengusaha berbagi inspirasi dan berkebun. Ini bertujuan untuk agar peserta didik tertanam jiwa, karakter tanggung jawab, dan kepemimpinan. Pelaksanaan dilakukan pada peoses belajar mengajar, ektrakulikuler, dan mata pelejaran kewirausahaan, penelitian ini dapat memberi informasi kepada sekolah-sekolah lain dalam menerapkan dan menumbuhkan jiwa kewirausahaan peserta didik.
The Effect of Inquiry-Based Science Teaching Approach on Self- Concept of Secondary School Physics Students in Kitui County, Kenya
Authors: John Kunga , Embeywa Henry , Koech Peter 
Published: March 2021

Purpose: The study sought to investigate the effect of Inquiry-Based Science Teaching Approach on learners’ self-concept of secondary school physics students in Kitui County, Kenya.
Methodology: The study adapted Quasi Experimental Research Design and in particular the Solomon’s Four Non-Equivalent Control Group Research Design. The target population of the study was 1600 form four Physics students from 40 Extra-County secondary schools in Kitui County. Stratified random sampling was used to select four Extra-County schools (2 Girls and 2 Boys). Purposive sampling was used to select 40 students from each of the four schools and a Physics teacher from each of the two sampled schools; giving a sample size of 160. A students’ questionnaire on self- concept was the research instrument. A reliability coefficient of 0.776 was obtained. Both descriptive and inferential data were analysed. The descriptive analysis was by means of frequencies, means, standard deviation and percentages. Inferential analysis was through Analysis of Variance, Chi-square and the Least Significant Difference (LSD) technique at a significance level of coefficient alpha α=0.05.
Findings: The results showed a statistically significant difference in self-concept between students taught using IBSTA and those taught by the conventional methods. The study established that out of the four indicators of self-concept, only role performance was not statistically significant. Consequently, the study concludes that IBSTA is effective in improving students’ self-concept.
Unique contribution to theory, practice and policy: The theories were validated in that there was knowledge was actively constructed and need to prepare a learner to have a self -concept after learning. The researcher recommended that creation of an enabling environment for IBSTA be adopted in schools, an appropriate policy should be developed for diploma colleges and universities to train their teacher trainees with an emphasis on IBSTA as part of their Physics training curriculum and KICD should introduce and develop a programme for the Induction and Mentorship of Physics Teachers on the implementation of IBSTA so as to empower them with inquiry skills.
Regional history in literature, narratives and performance in Bengal and Santhal Pargana
Authors: Kumar Ranjan 
Published: March 2021

This is an attempt to study the regional history of Bengal with the help of literature and narratives and unheard past of Santhal Pargana through narrative performances. Since, the history was written for the ruling and aristocracy class which gives an understanding of the past from above and it hardly talks about the history of lower strata. There is a massive need of history writing pertaining to local areas. The knowledge of the local people is acquired through qualitative research because the indigenous knowledge is transferred from one generation to another and because of the west centric knowledge, the indigenous knowledge is marginalised which will even vanish after sometime. Similar is the situation of the knowledge of spiritual and religious past. The hagiographical literature of this region is considered as an important source to understand the socio- religious outlook. Beneath these literatures, there were several proto socio- religious outlooks that exercised a profound impact on people at lower level. In process to study these , one has to depend upon the oral history available in its surroundings.
Effect of Platelet-rich Plasma in Regeneration of Thin Endometrium and Its Implications in in vitro Fertilization Cycles: A Novel Approach
Authors: Pandey Kiran , Sahoo Gangadhar , Lal Pavika , Upadhyay Rashmi 
Published: March 2021

ABSTRACT
The thin endometrium is an important cause of failure of cycle cancellations in in vitro fertilization (IVF). Several modalities like estrogen, low-dose aspirin, heparin, vaginal sildenafil, pentoxifylline, and granulocyte-colony stimulating factor (G-CSF) intrauterine perfusion have been tried and studied in patients with a thin endometrium. We discuss platelet-rich plasma (PRP) administration by intrauterine infusion as a novel approach in these patients. We reviewed and analyzed all important and relevant articles including case series, pilot studies, and case reports published from January 2000 to December 2020. Studies pertaining to other uses of PRP were not included. We found that intrauterine infusion of PRP can significantly increase the endometrial thickness and improve the pregnancy rates in infertile patients with thin endometrium <6 mm.
How to cite this article: Pandey K, Garg R, Lal P, et al. Effect of Platelet-rich Plasma in Regeneration of Thin Endometrium and Its Implications in in vitro Fertilization Cycles: A Novel Approach. J South Asian Feder Obst Gynae 2020;12(5):313–316.
Comparison of Effectiveness of Diode Laser as an Adjunct to Scaling and Root Planing and Scaling, Root Planing Alone in Treatment of Chronic Periodontitis&mdash;A Randomized Split-mouth Clinical Study
Authors: Boloor Vinita , Hegde Shashikanth , Pooja Manjunath , Kashyap Rajesh S , Kumar Maiya A 
Published: March 2021

ABSTRACTAim and objectiveTo compare the clinical effects of diode laser (DL) as an adjunct to scaling and root planing (SRP) and SRP alone in the treatment of subjects with chronic periodontitis.Materials and methodsThirty subjects aged 25–54 years participated in this randomized split-mouth clinical study. All subjects with 60 selected sites were randomly divided into 2 equal groups depending on the treatment provided. Group I (control site): only SRP was performed at baseline and group II (test site): SRP along with DL irradiation was performed on day 7, 14, and 21. Clinical parameters plaque index (PI), gingival index (GI), bleeding index (BI), probing pocket depth (PPD), and clinical attachment level (CAL) were recorded at baseline and the end of 3 months for both groups.ResultsMean values of PPD from baseline to 3 months between groups I and II on the mesial and distal aspect showed a high statistically significant difference (p< 0.02). Mean values of CAL from baseline to 3 months between two groups on distal and buccal aspect showed high statistically significant difference (p< 0.02). On intragroup comparison, there was a decrease in a mean difference of PI, GI, and BI individually for both the groups from baseline to 3 months with (p< 0.001).ConclusionThe adjunctive use of 810 nm DL with SRP provides moderate additional clinical benefit in moderate periodontal pockets 4–6 mm.Clinical significanceThis study signifies that using noninvasive laser therapy, potential clinical benefits can be obtained in terms of reduction of periodontal parameters.How to cite this articlePooja M, Kashyap RS, Hegde S,et al.Comparison of Effectiveness of Diode Laser as an Adjunct to Scaling and Root Planing and Scaling, Root Planing Alone in Treatment of Chronic Periodontitis—A Randomized Split-mouth Clinical Study. J Contemp Dent 2019;9(3):117–123.
Lutas contra o Um
Authors: Tible Jean 
Published: March 2021

Este artigo propõe um diálogo entre duas abordagens; de Marx, por um lado, e da antropologia de P. Clastres e Viveiros de Castro, por outro. Trata-se de trocas acerca do Estado, a partir das respectivas concepções de abolição e recusa deste. Inicia-se com uma apresentação e justificativa desse diálogo, além de explanar também acerca de que Marx se está falando. Após colocar de modo inicial ambos os conceitos-chave e seus elos, tal encontro ganha outros desdobramentos, graças aos Mil Platôs de Deleuze e Guattari. Enfim, a análise de certas lutas, antigas e contemporâneas, que ambas as perspectivas trabalham do ponto de vista teórico, permite aprofundar tal proposta.
Relato de um impasse de pesquisa
Authors: Rui Taniele 
Published: March 2021

Este texto compartilha com o leitor impasses e dúvidas que durante quatro anos impediram uma visada analítica sobre a trajetória de Nando, descrita ao fim, apesar dos titubeios. Para compô-la, recorri a relatos produzidos desde 2003 (quando ele tinha treze anos), alguns por educadores de projetos socioeducativos, outros registrados em meus diários de campo. Ao narrá-la, viso esboçar um cotidiano e uma adolescência que se dão na circulação entre a rua, as instituições e a casa. Para além de um fracasso analítico, a trajetória de Nando revela também fracassos políticos. Por isso merece ser lida.