bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge of genetic eye diseases and genetic services and attitudes toward genetic testing and gene therapy
Authors: Ganne Pratyusha , Damagatla Manikanta , Naidu Navya Krishna 
Published: November 2021

PURPOSE:
Genetic eye diseases are among the top ten causes of ocular health burden. Asia accounts for nearly two-thirds of the global burden of genetic eye diseases. A great deal of resources is being invested in genetic research and development of genetic services including gene testing laboratories and genetic counseling in India. These efforts will be meaningful only if the public and clinicians are aware of their existence. This study aimed to understand the level of knowledge about genetic eye diseases and genetic services and attitudes toward genetic testing and gene therapy in four groups of participants (undergraduate medical students, paramedical staff, non-ophthalmologist doctors, and the general public).

MATERIALS AND METHODS:
This was a cross-sectional survey in India. Four hundred questionnaires were analyzed from the four groups of participants. Knowledge score was calculated for the different questions. To bring out the differences across the groups, Chi-square test was done with a post hoc Mann–Whitney U-test and Kruskal–Wallis test. P < 0.05 was taken as statistically significant.

RESULTS:
The level of awareness about genetic eye diseases was better among undergraduate students, doctors, and paramedical staff compared to the general public (P < 0.001). The majority across all three groups had a positive attitude toward genetic testing and gene therapy. However, most of the participants across all groups were not aware of the genetic facilities available in our country.

CONCLUSION:
This study shows a positive attitude toward genetic medicine. However, there is a need to improve public awareness about genetic eye diseases and facilities available for genetic testing and gene therapy.
Advanced technology of growing fodder beet seeds in the Central Forest Steppe of Ukraine
Authors: Balahura O. V. , Balan V. M. , Doronin V. A. , Volokha M. P. 
Published: November 2021

Goal. To improve the technology of growing fodder beets in the Central Forest-Steppe of Ukraine based on the study of agro-climatic indicators, patterns of plant growth and development.
Methods. Laboratory and field, analytical, statistical.
Results. The article is devoted to the theoretical and experimental substantiation of the parameters of the advanced technology of growing fodder beet seeds by spring sowing under the cover of corn. With this technology, seed bearing plants acquire new biological characteristics: before the onset of stable cooling, slightly larger woody roots with a high content of dry matter (20–22%) and sugar (16–17%) are formed with a well-developed leaf apparatus; due to the remaining stubble after harvesting cover crops (corn) increases the safety of plants in winter, which over the years of research was 89–96%, which provided a plant stand density at harvest of 177–180 thousand/ha, seed yield of 1.6–2.2 t/ha with a germination of 90–94%. Production testing of advanced technology has fully confirmed the field research. On average for two years the seed yield was 1.9 t/ha (control 1.5 t/ha), its cost decreased by 2.3 times compared to the control, the profit from the sale of seeds amounted to 7963 UAH/ha (control 2337 UAH/ha). The total profit on advanced technology, including due to the profit from the green mass of corn, amounted to 9133 UAH/ha, which is 3.9 times higher than in the control.
Conclusions. In the Central Forest-Steppe of Ukraine, it is expedient to grow fodder beet seeds according to an advanced technology, which stipulates row spacing of 60 cm, seeding rate of beet seeds per 1 m of a row 50–60 and corn 8–12; 2) harvesting corn before wintering at the time recommended for this area and depending on the purpose of use; 3) at the onset of stable cooling — hilling plants with simultaneous feeding (N40–50 P60–90 K30–50 kg/ha etc.) with paws-hillers of row cultivators (УСМК‑5.4Б, КОЗР‑5.4, etc.); 4) after overwintering — local application of nitrogen fertilizers (N80–120 kg/ha, etc.) + harrowing with heavy or medium harrows across the rows or diagonally; 5) in the stage of a well-developed rosette — application of inter-row (local) nitrogen-phosphorus fertilizers (N20–30, P40–60 kg/ha, etc.) using МТЗ‑1025+УСМК‑5.4Б (КРН 56–02); 6) in the stage of mass stalking — removing of top foliage using МТЗ‑1025+КС‑2,1; 7) during flowering — two or three additional pollination.
The inﬂuence of nitrogen fertilizers on the productivity of energy biomass of willow
Authors: Vokalchuk B. M. , Fuchylo Ya. D. 
Published: November 2021

Purpose. Determine the optimal rate of nitrogen fertilizers for fertilizing energy plantations of willow before the start of the second three-year cultivation cycle in the Central Forest-Steppe of Ukraine.
Research methods. Field, analytical, statistical.
Results and discussion. Appling of ammonium nitrate contributed to the active beginning of the growing season and the increase in the plant mass in hight. At the end of the first year of vegetation, the tallest plants were formed in variety ‘Tora’ using N70 – 4.67 m, which is more than in the control version (without fertilizer) by 0.71 m, or 16%. For N35, the average plant height was 4.32 m, which is 8% more than the control. The formation of more tall plants to restore more nitrogen was found in the variety’Ternopilska’. Hight of annual plant of this variety in control was 3.68 m, for application N35 – 4.08 m, and for dose N70 – 4.24 m. At the end of the second growing cycle, the average height of plants of the variety ‘Tora’ in control variant was 6.29 m. The highest plants with the distribution of ammonium nitrate in the maximum dose (N70) were 6.78 m, which is more than in control variant by 8%. For the application of N35, the height of plants of the plantation was 6.52 m and 5.79 m. In this case, the decrease in the share affects the height of plants up to 15.4%, and the share affects the varietal characteristics of growth up to 82.9%. Also nitrogen had a positive effect on biomass growth. The yield of dry biomass of three-year-old energy willow plantation in the other part of cyclic production under control (without fertilizers) was 65.3 t/ha (21.8 t/ ha/year) of dry biomass in ‘Tora’ variety, and 55.6 t/ha (18.5 t/ha/year) in ‘Ternopilska’ variety. In the variants with the use of ammonium nitrate in the dose of N35, the indicator increased due to the control in variety ’Tora’ by 2.8 t/ha and by 3.7 t/ha in the variety ’Ternopilska’. Increasing the nitrogen dose to N70 increases the yield of dry biomass in the varieties’Tora’ and ’Ternopilska’ by 8.8 t/ha and 9.3 t/ha, respectively, compared to the control.
Conclusions. The application of ammonium nitrate and varietal characteristics have a significant impact on the yield of energy biomass of willow. Of the two studied varieties of willow on chernozem soil of the Central Forest-Steppe of Ukraine, the variety’Tora’ was noted for more intensive growth and higher productivity during the second three-year growing cycle. Plants of both varieties are characterized by higher yields for nitrogen application at a dose of 70 kg/ha a.i.
Prospects of using pine in agriculture on agricultural land in Polissia of Ukraine
Authors: Fuchylo Ya. D. , Ivaniuk I. D. , Makukh Ya. P. , Yukhnovskyi V. Yu. , Remeniuk S. O. , Kusik V. M. 
Published: November 2021

Goal. Study of peculiarities of growing pine stands and prospects of their use in agroforestry of Zhytomyr Polissia on the example of agricultural lands of Malyn Vocational College.
Methods. Field, laboratory, analytical, statistical.
Results. On sod-podzolic sandy soils of Zhytomyr Polissia pine seedlings after three years of cultivation were 55.7 ± 3.43 cm in height. The maximum increase in height was observed during the third year of cultivation of the plantation, when at the beginning of the growing season with herbicide Targon Plus the impact of cereal vegetation reduced to a minimum, resulting in improved seedling growth conditions. The high preservation of pine plants and their intensive growth allow us to make optimistic forecasts about the feasibility of growing them as a forest component of agricultural landscapes, especially given the presence of biotically stable 15-year-old pine plantations created by similar agricultural techniques. They were laid at an initial density of 7.1 thousand seedlings per 1 ha, and later thinned to 2982 and 1691 plants/ha, respectively. With almost the same productivity indicators, higher tree height (by 17.0%) and larger average diameter (by 23.8%) allow thinner plantations to have a more positive impact on adjacent agricultural lands, grow more intensively and have higher productivity in the future. This indicates the expediency of pine plantations in the region of research as a forestry component of agrolandscapes a density at the age of 15 years of about 1700 trees per 1 ha.
El desarrollo económico comunitario. Diagnóstico socioeconómico de cien comunidades
Authors: Montoya Aquiles 
Published: November 2021

En este artículo, el autor presenta un estudio sobre el nivel de desarrollo de 100 comunidades -ubicadas en 10 departamentos del país- conformadas por repatriados, repobladores y combatientes desmovilizados, a quienes se les considera parte de una nueva estrategia denominada Desarrollo Económico Comunitario. Estas comunidades buscan, de manera colectiva y organizada, desarrollar las actividades económicas para resolver sus problemas de pobreza y marginación. Aunque los resultados no son por completo satisfactorios, el autor considera que "la mayor riqueza del esfuerzo comunitario no está en lo logrado sino en sus posibilidades".
ECA Estudios Centroamericanos, Vol. 53, No. 595-596, 1998: 473-496.
Routing Optimization for Road Administration Vehicles with Consideration of Overloaded Truck Detour Behavior on Rural Highways
Authors: Jiang Jinyu , Yang Zhongzhen 
Published: November 2021

Abstract
In response to the increasingly frequent detour behavior of overloaded trucks attempting to avoid overload inspection and punishment, this article develops a bilevel programming model to optimize the routes of road administration vehicles by simulating the capture and anticapture interaction between administration vehicles and overloaded trucks. The upper-level model determines the optimal patrol routes of administration vehicles to maximize the number of overloaded trucks that can be captured. The lower-level model deduces the detour routes of overloaded trucks based on their circumvention behavior relative to administration vehicles. To solve the bilevel programming model, this article proposes a heuristic algorithm combining the ant colony algorithm and the labeling algorithm. To validate the proposed model and algorithm, this article uses actual rural highway data for Guiyang, China. The result proves the feasibility and superiority of the proposed programming model and algorithm. Compared to traditional overload management techniques, considering the detour behavior of overloaded trucks in optimizing the routing of road administration vehicles improves the effectiveness of overload management by up to 1.65 times.
Carpintería de armar con lacería en iglesias de la región de Murcia. Conceptos básicos y características de estas techumbres de madera
Authors: Collado Espejo Pedro Enrique 
Published: November 2021

A principios del siglo XVI, el Reino de Murcia experimenta un notable aumento de población que conlleva la construcción de numerosas iglesias. En general, estos nuevos templos se caracterizarán por el sistema de techumbre de madera a base de carpintería de armar con lacería. En muchos textos, a estas construcciones históricas se les ha denominado como “iglesias mudéjares” o “iglesias moriscas”, y su tipología ha sido relacionada con los modelos granadinos, sevillanos, levantinos (por el uso de arcos transversales o diafragma) o castellanos, dependiendo del autor que analizara estas construcciones. El presente texto pretende exponer las características formales y constructivas de estas iglesias y sus techumbres de madera, los sistemas de aprendizaje y trabajo de los autores de las cubiertas (bajo el control de los gremios de carpinteros y regulado por las correspondientes ordenanzas), y justificar por qué no se deben atribuir estas edificaciones a carpinteros mudéjares o moriscos sino a carpinteros procedentes de áreas de Castilla y por qué deberíamos denominar estos trabajos como carpintería de lazo. Con ello, se pretende contribuir al conocimiento y difusión de estas magníficas soluciones estructurales y decorativas de carpintería de armar, con lacería, que aún se conservan el nuestra Región, contribuyendo así a su conservación.
At the beginning of the 16th century, the Kingdom of Murcia experienced a notable increase in population that led to the construction of numerous churches. In general, these new temples will be characterized by the carpentry-based wooden roof system of arming with lacework. In many texts, these historical constructions have been called "mudejar churches" or "moorish churches", and their typology has been related to the Granada, Sevilla, Levantine (due to the use of transverse arches or diaphragm) or Castilian models, depending on the author who analyzed these constructions. This text aims to expose the formal and constructive characteristics of these churches and their wooden roofs, the learning and work systems of the authors of the roofs (under the control of the carpenters' unions and regulated by the corresponding ordinances), and justify why these buildings should not be attributed to “mudejar” or moorish carpenters but to carpenters from areas of Castile and why we should call these works as laced carpentry. With this, it is intended to contribute to the knowledge and dissemination of these magnificent structural and decorative carpentry solutions to be assembled, with lacework, which are still preserved in our Region, thus contributing to their conservation.
De la mise en oeuvre d’un ERP aux prismes des situations extrêmes et de la théorie de la structuration : une étude de cas dans une industrie pétrolière
Authors: Ait-Taleb Nabil , Lièvre Pascal 
Published: November 2021

La mise en oeuvre d’un ERP est appréhendée comme une situation extrême, car elle cumule de la rupture, de l’incertitude et du risque. Nous abordons cette question dans le cadre du courant structurationniste, en mobilisant le modèle de Giddens. Nous introduisons l’outil technique comme un facilitateur en tant que ressource artefactuelle, dans le registre de la domination. A partir d’une étude de cas, nous montrons que ce modèle est pertinent pour rendre compte des blocages en matière d’appropriation d’un ERP, mais inadapté pour rendre compte de l’apprentissage des acteurs, dans un contexte où la dimension informelle prend une place importante.
Study into the Development of a Light Weight Smart Life Buoy Prototype (LWSLB)
Authors: Thanakodi Suresh , Talib Muhamad Lazim , Ali Syarifah Aishah Syed , Wahab Norshahriah Abdul , Ahmad Amalina Farhi , Noor Norshaheeda Mohd , Zahari Muhammad Izham Bin Ahmad , Ahmad Mohd Arif 
Published: November 2021

Life Buoy, also known as a life preserver, is a crucial safety tool on board any marine ships. The most common and conventional lifesaver is operated manually to save people from drowning, yet this method poses a risk for both the victim and rescuer. Hence, with the help of current technology, a smart lifebuoy has been developed, whereby the rescuer just operates the lifebuoy using remote control. Yet, the existing smart life buoy system has been found heavy and hard to be operated, especially for women, children, and other people with disabilities.This paper focuses on the development of a lightweight smart life buoy system and its characteristics. Arduino Uno R3, Arduino Nano, DC motor 775, Transmitter and Receiver kit were the main components used in the development of the lightweight smart life buoy system (LWSLB). The developed LWSLB system was tested at the National Defence University of Malaysia’ swimming pool due to Covid-19 lockdown, and data such as speed, range of remote connection and battery endurance were obtained. It has been found out that the developed LWSLB weighs just 3.5kg overall compared to Brand S which weighs 13.75kg. However, in terms of speed, Brand S proves to be faster at 4.17m/s compared to LWSLB which exhibits a speed of 1.25m/s.
Analysis of the Microbial Quality of Locally Consumed Palm Wine Sold in Elele Community of Rivers State Nigeria
Authors: Ikeh I. M. , Anele B. C. , Ukanwa C. C. , Njoku S. O. 
Published: November 2021

Palm wine is generally consumed due to its nutritive composition to the human body system particularly when fresh and unfermented state. A total of 20 Palm wine samples obtained from two different locations in Elele community of Rivers state, were analyzed for their microbiological qualities. A ten-fold serial dilution method was used. For Total Aerobic Plate Count (TAPC) nutrient agar was used, MacConkey for coliform count (CC), Eosin methylene blue for Escherichia coli count (EC), and Potato dextrose agar for the fungal count. Microbial counts in the palm wine sold in the drinking bar were higher than that of the palm wine tapper. TAPC, the sample from the drinking bar has a mean value (6.73+ 0.22 log10cfu/ml) which was higher than the value obtained from the palm wine tapper (6.70+0.15log10cfu/ml). The coliform count of palm wine from the drinking bar was (6.57+ 0.10log10cfu/ml) but not significantly different from those with minimum counts (6.56+ 0.9log10cfu/ml) obtained from the tapper. Escherichia coli of palm wine from drinking bar were (5.73+ 0.23 log10cfu/ml) which were higher than (5.71+ 0.18 log10cfu/ml). The Fungal counts of palm wine sampled from the drinking bar were higher but not significantly different from those obtained from the tapper. Bacteria isolated from the two respective palm wines sampled included Staphylococcus spp 50% and 30% respectively, Klebsiella spp 20% and 30% respectively, Proteus spp 40% and 10% and 30% respectively, Aspergillus spp 30% , 10% and Saccharomyce cerevisae 20% and 30% respectively. For the analysis of variance, bacteria and fungi count was not significant. Consumers of palm wine are advised to purchase the product from the tapper to reduce the chances of contamination.
Workforce Skill Development Policy Guideline for Industrial Revolution in Thailand
Authors: Tuenpusa Pongpith 
Published: November 2021

An article presents policies for Thailand's workforce development under the context of the 4th Industrial Revolution. It will be helpful for executives to design policies to improve the country's workforce. Within context, the changes from the impact of the Industrial Revolution were due to the influence of Disruptive Technology. The paper explores directions, trends, impacts, and policies for managing labor issues in the Disruptive Technologies era. Studying the opinions of 26 CEOs and executives of businesses in Thailand(2019-2020) used or affected by the Industrial Revolution, obstacles, feedback, focusing on issues, concepts about Disruptive Technologies, and vocational education concepts.
They are using qualitative research methodology and procedures to support policy. The study results are the impact of Industrial Revolution on Thai workers and technological TVET Institution to develop Thai people during Industrial Revolution, educational management to develop Thai people in the Thailand 4.0 Therefore focuses on increasing labor skills and educating to create new skill / Upskill /Reskill for workers under reality.
The policy document also outlines recommendations from the public and private executives. The CEOs have advised on the issue of developing the skills and performance of the workforce in the future. The changes in the skills of older workers and summary provide policy recommendations to educational institutions and governments.
Frequency of Acute Ischemic Stroke in Patient with Type-II Diabetes Mellitus: Descriptive Cross Sectional Study
Authors: Khan Salman , Malik Zubair , Khan Nisar , Mojai Sajid Ali , Rehman Ata Ur , Khan Alamgir , Khan Muhammad Ismail , Ullah Najeeb , Jan Hafiz Tahsin Ullah , Ahmed Tahseen 
Published: November 2021

Aim: To evaluate the frequency of acute ischemic stroke in patients with type-II diabetes mellitus.
Study Design: Descriptive Cross sectional Study
Place & Duration of Study: The study was carried out at Department of Medicine, DHQ Teaching Hospital, Dera Ismail Khan for the period of 06 months from 06 Feb, 2018 to 06 Aug, 2018.
Methodology: All patients admitted through OPD presented with type-II diabetes mellitus and having acute ischemic stroke after radiological confirmation using non-contrast enhanced CT scan brain with type-II diabetes (as per operational definitions above) were enrolled in study. Informed written consent was taken by the researcher with detailed history followed by detailed clinical examination and all patients who was give their consent to participate in the study was questioned about their medical history and was examined in detail for their neurological deficits. All the laboratory investigation was done from single hospital laboratory and all the radiological investigations were done from hospital radiology department.
Results: As per frequencies and percentages for acute ischemic stroke, 215 (74.65%) patients were found having acute ischemic stroke.
Conclusion: In this study, we concluded that there is a significant age difference between the diabetes-stroke co-morbid patient and non-diabetic stroke patient. Therefore, health education on preventive measures for type 2 DM, adequate regulation of blood pressure and blood sugar level through compliance to medical advice and medication, regular clinic attendance and periodic measurement of blood pressure and blood sugar level.
Formulation and Evaluation of Ibuprofen Fast Dissolving Tablets Employing Starch Malonate (Modified Starch) as a Superdisintegrant
Authors: Kumari Annu , Kumar R. Santosh 
Published: November 2021

Aim: The goal of the study was to prepare a superdisintegrant named starch malonate followed by its evaluation for physicochemical properties. Prepared starch malonate was optimized in the preparation of fast dissolving tablets of ibuprofen by using 23 factorial designs.
Methods: Compatibility studies like FTIR, TLC and DSC were performed to check any interaction between starch malonate and ibuprofen. Fast dissolving tablets were compressed by direct compression method and subjected to various official tests like hardness, friability, drug content, dissolution etc. Wetting time and water absorption ratio were also performed. At last response surface plot and contour plot was plotted to check the effects of starch malonate, croscarmellose sodium and crospovidone (independent variables) on disintegration time and dissolution efficiency in 5 minutes (dependent variables). Stability studies were also performed to check the stability of prepared fast dissolving tablets of ibuprofen.
Results: Results of the studies showed that all the results are within acceptable limits and complying with the criteria of fast dissolving tablets. Drug content was found to be (100±5%), hardness of all tablets were found in between 3.8 -4 kg/cm2, friability was found less than 0.15%. Optimized formulation has showed less wetting time, less disintegration time followed by enhanced drug release. Among all formulation, formulation F2 has shown least disintegration time and enhanced drug release (99.89%) as compared to other formulations. We can conclude that starch malonate can be used as a novel superdisintegrant.