bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emergency mental health calls to first responders following a natural disaster
Authors: Saunders John , Dongarwar Deepa , Salemi Jason , Schulte Joan , Persse David , Matin Asna , Banu Sophia , Shah Asim 
Published: March 2021

Introduction:
Hurricane Harvey which made landfall on August 25, 2017 was a devastating storm that dumped unprecedented amount of rainfall on the area including Houston, Texas, United States of America. There are limited data about emergency service mental health utilization following disaster events. The goal for this project was to examine mental health calls to emergency medical services (EMS) and to the Houston Police Department following Hurricane Harvey. An analysis looking at this utilization following a natural disaster represents an understudied area and can potentially provide information about city services and community psychiatric services in the acute period following the event.

Materials and Methods:
Total number of calls to the police department and mental health calls to the police department described as crisis intervention calls (Crisis Intervention Team) were obtained from August 1, 2016 to October 31, 2016 and January 1, 2017 to December 31, 2017. Emergency detention orders (EDO) per date were obtained from January 1, 2017 to December 31, 2017. Data for mental health calls based on the primary impression of mental health complaint were obtained from the Houston Fire Department for EMS from January 1, 2016 to December 31, 2017.

Results:
There was a statistically significant increase in the number of mental health calls to the police following Hurricane Harvey. When comparing the prestorm, active storm, and poststorm period, there was not a statistically significant difference in the number of EDOs or the number of EMS mental health calls.

Conclusions:
The increase in police mental health calls suggests that there may have been an increase in the acuity of the mental health calls to EMS around in evaluating calls surrounding the period of Hurricane Harvey.

The following core competencies are addressed in this article:
Medical Knowledge and Patient Care.
Hypophosphatasia
Authors: Chamakkala Tess , Gallagher Thomas 
Published: March 2021

Hypophosphatasia is a disorder of bone metabolism due to defective tissue nonspecific alkaline phosphatase (ALP). It is most severe in early life but can present at any age, leading to a likely underdiagnosis of its adult, and commonly less severe, forms. This is the case of a 42-year-old female who presented to endocrinology asking about her low ALP levels in the setting of prior bilateral metatarsal fractures and was diagnosed with hypophosphatasia. This case report aims to highlight the importance of making this diagnosis in order to avoid commonly prescribed therapies that can be harmful. Antiresorptive therapies as well as supplementation with calcium or Vitamin D can potentially worsen the disease. There are no Food and Drug Administration-approved treatments for adult hypophosphatasia, but asfotase alfa and teriparatide are two promising therapies currently being studied.

The following core competencies are addressed in this article:
Practice-based learning and improvement, Medical knowledge.
Application of microsatellite markers for hybrid verification and genetic analysis of oil palm (Elaeis guineensis Jacq.)
Authors: Okoye M.N , Singh R , Uguru M.I , Bakoumé C 
Published: March 2021

The legitimacy of parents and progenies used in crop improvement programmes is vital for any meaningful progress in selection. While acknowledging the shortcomings of controlled pollination in oil palm breeding and commercial seed production, the legitimacy of 20 oil palm progenies from the Nigerian Institute for Oil Palm Research (NIFOR) breeding programme was determined using 16 fluorescently-labeled microsatellite markers. The genotyping of parents and progenies was conducted by capillary electrophoresis using the ABI 3730 DNA Genetic Analyzer (Applied Biosystems, USA). Results revealed a complementary expression of the parents’ alleles in 18 out of the 20 individual progenies screened, confirming their hybridity and genetic identity. The two illegitimate progenies detected could be attributed to pollination and planting errors, respectively. A subset of three sufficiently informative loci (sMg00016, sMg00179 and sMo00102) was identified for routine quality control genotyping. The detection of illegitimate progenies provided ample evidence to substantiate the importance of assessing hybrid fidelity in breeding programmes. Furthermore, the usefulness of microsatellite markers as a reliable technique for routine assessment and unambiguous identification of oil palm crosses was established. The implications of microsatellite- based hybrid identification in oil palm varietal improvement programmes have been adequately discussed.
Key words: Contamination, Genetic identity, Illegitimacy, NIFOR, Parent-Progeny relationships, seed production
Effects of Momordica Charantia Silver Nanoparticles on the expressions of Genes Associated With Lipid Metabolism and Nephrotoxicity in Streptozotocin-Induced Rats
Authors: Elekofehinti O.O , Akinjiyan M.O 
Published: March 2021

Hyperlipidemia and hyperglycemia have been implicated in diabetes mellitus (DM) leading to complications such as nephropathy. Medicinal plants like Mormodica charantia (MC) have been used in the treatment of DM over the years but little is known about their mechanisms of action. This study used biotechnology tools to investigate and compare the effects of M. charantia silver nanoparticles (MCSNPs) with M. charantia extract on expressions of genes linked with nephrotoxicity, lipid and glucose metabolisms using reverse-transcriptase polymerase chain reaction (RT-PCR) in streptozotocin-induced diabetic rats. The genes investigated include kidney injury molecule-1 (KIM-1), 3-hydroxyl, 3-methyl glutaryl_coA reductase (HMG-CoA reductase), peroxisome proliferator-activated receptor alpha and gamma (PPARα and PPARγ). Synthesis of MCSNPs was done using 1 mM concentration of aqueous silver nitrate solution at ratio 1:9 (v/v). Experimental rats were induced intraperitoneally with streptozotocin (65 mg/kg) and divided into six groups viz: diabetic control; normal control; silver nitrate (10 mg/kg); MCSNPs (50 mg/kg); Metformin (100 mg/kg) and M. charantia fraction (100 mg/kg). Sacrifice was done after 12 days of treatment and RT-PCR was then used to investigate gene expressions in liver and kidney tissues of the rats. The expression of HMG-CoA reductase gene was significantly upregulated (p<0.05) upon treatment with 50 mg/kg MCSNPs relative to the diabetic untreated group. M. charantia extracts and MCSNPs significantly upregulate (p<0.05) the expressions of PPAR-α and PPAR-γ compared to the diabetic control. Also, a significant (p<0.05) down-regulation of KIM-1 mRNA expression was observed in MCSNPs- treated group, relative to the diabetes untreated group. M. charantia silver nanoparticles could be a potent antidiabetic agent due to its potential to modulate genes associated with lipid metabolism and nephrotoxicity.
Keywords: Medicinal plant; Diabetes Mellitus; Silver Nanoparticles; nephrotoxicity; gene expression
Nutritional properties of indigenous fermented condiment (ogiri) produced from partial substitution of castor oil bean (Ricinus communis) with soybean (Glycine max) seeds
Authors: Okwunodulu I.N. , Agha E. F 
Published: March 2021

Recently, in Nigeria, there has been a series of controversial publications and debates over the use of seasoning cubes and monosodium glutamate as cancer inducing agents. With this, the use of local condiments like Ogiri has become an option. Ogiri is traditionally produced from castor oil beans which is scarce in some communities. This study therefore explored the possibility of substituting castor oil bean with soybean to obtain an acceptable Ogiri. Proximate, mineral and vitamin composition and sensory characteristics of the substituted Ogiri samples produced were evaluated using standard methods. With increase in soybean substitution levels, proximate analysis showed an increase in crude protein (17.33%-31.68%), crude fibre (0.47-1.71%) and fat (13.76-20.23%) contents while ash (3.63-3.21%) and carbohydrate (48.13%-23.55%) contents decreased. Mineral contents increased from 46.11 - 80.21, 60.25 - 73.83, 80.33 - 99.42, 118.10 - 794.38, 1.63 - 6.32 and 0.49 - 1.48 mg/100g for calcium, magnesium, phosphorous, potassium, iron and zinc, respectively. Potassium was the most abundant mineral in the samples. Also, retinol (11.63-16.26 mg/100g), vitamin B1 (0.10-0.21 mg/100g), vitamin B2 (10.37-14.79 mg/100g), vitamin B3 (9.21-9.91 mg/100g), vitamin C (2.43-5.85 mg/100g) and vitamin E (6.43-11.25 mg/100g) increased significantly. Sensory analysis revealed that the Ogiri sample with 50% soybean inclusion and the control had the best organoleptic properties. Therefore, soybean substitution of up to 50% gave a better acceptable Ogiri with improved nutrient contents.
Keywords: “ogiri”, castor oil bean, soybean
Evaluation of electrochemotherapy in the management of apocrine gland anal sac adenocarcinomas in dogs: A retrospective study
Authors: Valenti Paola , Menicagli Francesco , Baldi Alfonso , Barella Gabriele , Catalucci Chiara , Attorri Valeria , Spugnini Enrico P. 
Published: March 2021

Background: Electrochemotherapy (ECT) combines the administration of anticancer drugs with the delivery of electric pulses, thus increasing the drug uptake through the cell membranes, resulting in increased efficacy.
Aim: The aim of our study was to describe the tolerability and efficacy of ECT alone or in association with other treatment modalities for the management of apocrine gland anal sac adenocarcinoma (AGASAC).
Methods: Medical records of dogs with a diagnosis of AGASAC that were treated with ECT alone or in combination with surgery/chemotherapy were retrospectively evaluated. Each dog received 20 mg/m2 of bleomycin intravenously. Based on the clinician’s decision, the primary tumor or tumor bed was also infiltrated with cisplatin at the dose of 0.5 mg/cm2. Trains of permeabilizing biphasic electric pulses were then applied under general anesthesia.
Results: Ten dogs were enrolled in the study. Of those 10 dogs, only one received ECT for treatment of microscopic local disease, while in six cases ECT was the only treatment modality. In three dogs, ECT was followed by systemic medical treatment. Six dogs (60%) had a partial response (PR), three dogs (30%) had stable disease, and one dog treated for microscopic disease did not show any sign of local relapse for 305 days after treatment, being still alive and in complete remission at the time of writing this article. The median time to progression was 303 days and the median survival time was 365 days. The treatment was well tolerated and local side effects were minimal. No systemic effects were documented.
Conclusion: This preliminary study suggests that ECT may be beneficial for dogs with AGASAC and could be a useful addition to the current therapeutic options in consideration of its low cost, limited toxicity, and ease of administration.
Hubungan Kemudahan Akses Terhadap Perilaku Penggunaan Rokok Elektrik pada Mahasiswa di Universitas Muhammadiyah Kalimantan Timur
Authors: Sunarti Sri 
Published: March 2021

Merokok merupakan hal yang menjadi ancaman bagi kesehatan karena menyebabkan 7 juta jiwa meninggal dunia per tahun. (1) Tujuan: Untuk mengetahui Hubungan Kemudahan Akses Terhadap Perilaku Penggunaan Rokok Elektrik pada Mahasiswa di Universitas Muhammadiyah Kalimantan Timu. (2) Metode : Penelitian ini merupakan penelitian kuantitatif dengan menggunakan metode penelitian analitik , dengan desain Cross-Sectional. Sampel penelitian ini adalah mahasiswa/i Program Studi Kesehatan Masyarakat Universitas Muhammadiyah Kalimantan Timur sebanyak 214 responden dan dilaksanakan pada bulan Juli 2020 yang dipilih menggunakan Stratifite Random Sampling dengan menggunakan kuesioner. (3) Hasil: Hasil uji statistik menunjukan bahwa 8,4% responden menggunakan rokok elektrik. Analisis Chi Square menunjukan bahwa ada hubungan yang signifikan antara kemudahan akses P=0,008; OR=4,899 dengan perilaku penggunaan rokok elektrik pada Mahasiswa di Universitas Muhammadiyah Kalimantan Timur. (4) Simpulan : sehingga Adanya hubungan antara variabel kemudahan akses dengan perilaku penggunaan rokok elektrik pada mahasiswa di Universitas Muhmmadiyah Kalimantan Timur (p=0,008)
Hubungan Gaya Hidup dengan Kejadian Hipertensi Di Wilayah Kerja Puskesmas Geneng, Ngawi
Authors: Nurmandhani Ririn 
Published: March 2021

Penyakit Hipertensi sangat di pengaruhi oleh gaya hidup sehari-hari. Hipertensi atau tekanan darah tinggi adalah peningkatan tekanan darah sistolik lebih dari 140 mmHg dan tekanan darah diastolik lebih dari 90 mmHg. Hipertensi juga sering disebut dengan pembunuh diam-diam (the silent killer) karena seringkali orang yang menderita hipertensi selama bertahun-tahun tidak merasakan suatu gangguan atau gejala. Data penderita hipertensi di Ngawi, berdasarkan data Dinas Kesehatan Kabupaten. Ngawi tahun 2016 sebanyak 10.042 orang penderita, kemudian pada tahun 2018 sebanyak 10.302 orang penderita. Angka prevalensi hipertensi diperkirakan akan terus meningkat, mengingat gaya hidup yang serba mudah, usia seseorang meningkat, kemiskinan, dan akses pelayanan kesehatan yang kurang memuaskan. Tujuan penelitian ini adalah untuk mengetahui hubungan antara gaya hidup dengan kejadian hipertensi di Wilayah Kerja Puskesmas Geneng. Jenis penelitian ini adalah suatu penelitian Kuantitatif dengan desain studi Cross Sectional. Pengambilan sampel dilakukan dengan teknik Purposive Sampling dengan sampel 69 orang penderita hipertensi. Uji statistik menggunakan Korelasi Spearman dengan kemaknaan α0,05.Hasil penelitian menunjukkan bahwa ada hubungan antara gaya hidup dengan kejadian hipertensi dengan nilai signifikan (p) = 0, 000 dimana ≤ α = 0,05 dengan nilai korelasi r=0,787 dengan demikian maka dapat dikatakan ada hubungan yang bermakna antara gaya hidup dengan kejadian hipertensi di Puskesmas Geneng.Berdasarkan hasil penelitian tersebut diketahui bahwa ada hubungan antara gaya hidup dengan kejadian hipertensi. Disarankan bagi responden atau masyarakat di Puskesmas Geneng agar meningkatkangaya hidup yang sehat dengan cara meningkatkan pola hidup bersih dan sehat serta menghindari hal-hal yang dapat menimbulkkan penyakit hipertensi seperti mengkomsumsi makanan asin dan awetan, berlemak dan jeroan, tidak mengkomsumsi minuman beralkohol dan berkafein, sering berolahraga, tidak merokok dan tidak stress.
SOCIALIZATION OF THE DANGER OF DRUGS TO IMPROVE COLLAGE STUDENT'S AWARENESS
Authors: Hartono Wira Jaya , Fachrurozzie Ryone 
Published: March 2021

Drugs are not a dangerous thing if they are used by the experts in medication, but in this case drugs such as crystal meth is consumed by colleagues or university students freely will impact their emotionally and physically. In result it will impact their future to become worse and worse. STMIK Dhamarpala Riau is a college located in central Pekanbaru city. It has freedom of interaction in all aspects, moreover the majority of students are workers. So they become a fresh bait by drug distributors. To prevent that happen and improve their awareness, this is important to give socialization about the danger of drugs in order to avoid bad things occur and they will not trapped in drugs situation. This program is also supported by the National Anti Narcotics Agency of Indonesia. The writer as anti narcotics activators socialize about the definition of drugs, how to recognize drug users, and how to make an anticipation of drug users at the level of family, friends and society.
Key Words: Danger of drugs, university student
TIME MANAGEMENT SKILLS FOR ENTREPRENEUR SUCCESS
Authors: Putra Riyan Sisiawan , Zuhdi Ubaidillah 
Published: March 2021

Waktu sangat penting karena waktu yang biasa terbuang sia-sia bisa jadi merukapan waktu yang berguna bahkan bisa menjadi peluang yang menghasilkan uang. Dalam pengabdian ini kami akan mengajarkan bagaimana cara mengatur waktu dengan baik sehingga nantinya para pelaku usaha bisa terbiasa menata waktu dan mencari peluang sebaik mungkin. Dengan menggunakan metode seminar online kami mendapatkan hasil :

memahami tentang wirausaha kreatif dan pentingnya menjadi seorang wirausaha
berkeinginan untuk membuka/merintis usaha baru
mempunyai ide-ide baru untuk usaha kreatif

Dengan dilaksanakannya kegiatan pengabdian masyarakat ini, diharapkan dapat membantu para pengusaha maupun masyarakat sekitar untuk berkembang dalam kondisi yang sedang bermasalah dengan baik.
Бастауыш сынып оқушыларын тұлға ретінде қалыптастыруда үштілділікті меңгертудің тиімділігі
Authors: Сағынбекова Еркежан Ризабекқызы  , Турганбаева Толганай Бокейхановна  
Published: March 2021

"Қоғамда болып жатқан әлеуметтік экономикалық өзгерістер мен еліміздің білім беру саласының әлемдік білім кеңістігіне шығуы – білім беру саласында, соның ішінде бастауыш мектепке заман талабына сай өзгерістер енгізіліп отыр. Қазіргі уақытта елімізідң негізгі стратегиялық міндеттерінің бірі білім беру жүйесін қайта құру және дамыту болып табылады. Бастауыш мектеп үздіксіз білім берудің алғашқы оқушылардың негізі қаланатын маңызды кезең. Сондықтан да бастауыш мектептің негізгі мақсаты баланың жеке ерекшеліктерін, қабілетін, дарыны мен талантын ашуға және жан-жақты дамытуға бағытталған. Мақалада қазіргі таңда өзекті болып отырған үштілдік тіл идеясы бойынша мәселе қарастырылмақ. Сондай-ақ, аталмыш мақала ана тілді құрметтеу, мемлекеттік тілді байыту және ағылшын тілін меңгерту мақсатында жазылып отыр. Үштілділікті меңгертудегі үштілділік бағдарламасы бойынша ағылшын тілін оқытуда баланың алған дағдылары мен әдістерін дамытып, нығайту үшін жағдай жасап, ұйымдастыру, міндетті түрде білім салаларымен жан-жақты байланыстылығы жайында сөз қозғалмақ. Шет тіліне оқыту жұмысын ойдағыдай жүргізу үшін балалардың жас ерекшіліктері мен жеке ерекшеліктерін, әрқайсысының зейін, қабылдау, еске сақтау, ойлау, қиялдау ерекшеліктерін, сезім, ерік, пен жеке дарындылық қасиеттерін жақсы біліп алу керек. Үштілділік идеясының бастауыш сынып оқушыларын тұлға ретінде қалыптастырудағы орны, тілді меңгерту ерекшелігі жайында баяндалады. "
El papel de la fotografía y el fotomontaje en el proyecto del Monumento a Aita Donostia (Jorge Oteiza y Luis Vallet)
Authors: Etxepare Igiñiz Lauren , García Nieto Fernando 
Published: March 2021

<p>Una vez que Jorge Oteiza definiera la estela en homenaje a <em>Aita Donostia</em> por encargo de la Sociedad de Ciencias Aranzadi, comenzaba el desarrollo, por parte de Luis Vallet, del proyecto arquitectónico para la capilla que iba a acompañarla. Vallet se encargó de integrar la estela, la capilla y los crómlech milenarios de Agiña, haciendo uso de la fotografía como herramienta de trabajo aplicada en todos los estadios de proyecto. Durante el proyecto, que arrancó en noviembre de 1956 y finalizó en verano de 1959, Oteiza y Vallet emplearon dos técnicas, la fotografía y el fotomontaje, y tres tipos de cámara fotográfica: una Weltaflex, una Polaroid y una Leica. Es hora de sacar a la luz los aspectos técnicos de los distintos reportajes, las influencias bajo las cuales fueron realizados y los motivos por los que optaron por una determinada técnica o cámara en cada una de las fases.</p>
Use of automatic refractometer infrared images to screen pigment dispersion syndrome: a cross-sectional observational study from a preliminary hypothesis
Authors: Brusini Paolo , Papa Veronica 
Published: March 2021

Background: This study was performed to evaluate the use of anterior segment images, obtained with an automatic refractometer, to identify early defects of the iris pigment epithelium in patients with pigment dispersion syndrome (PDS) or pigmentary glaucoma (PG) without observable alterations at the slit lamp.
Methods: In this cross-sectional observational study, carried out from January 2018 to December 2019, in Policlinico Citta di Udine Health Center, Udine, Italy, we observed anterior segment infrared images of 1700 subjects who were undergoing routine ophthalmological examination using an automatic refractometer. We selected infrared images of subjects who fulfilled the inclusion and exclusion criteria and looked for a focal defect in the iris pigment epithelium.
Results: Twenty patients with focal iris pigment epithelial defect were identified and none of them showed evident signs of PDS. After the necessary explanations, they agreed to have further examinations to verify the possibility of PDS. An in-depth evaluation of ocular structures, including gonioscopy, demonstrated the presence of PDS in all subjects with iris defects.
Conclusions: The use of infrared images obtained by an automatic refractometer could provide early and easy identification of PDS in crowded ophthalmology clinics or mass screening programs; yet, more well-designed studies are necessary to confirm these preliminary findings and prove this proposed screening tool.
Surgical versus optical treatment for anisometropia in adults: a randomized controlled trial
Authors: Iqbal Mohammed , Mahmoud Ali , Zarif Marcos , Gad Ahmad 
Published: March 2021

Background: We evaluated and compared outcomes of laser-assisted in situ keratomileusis (LASIK) versus optical spectacle correction for the treatment of anisometropia in adult patients.
Methods: This prospective, randomized controlled clinical trial included 50 eyes of 50 patients. We randomly allocated participants to Group A (25 eyes with anisometropia assigned to LASIK treatment) and Group B (25 eyes with anisometropia assigned to optical spectacle correction). All patients underwent preoperative and postoperative visual acuity, subjective and cycloplegic refraction, fundus, slit-lamp, and corneal topography examinations.
Results: In Group A, at 1-month postoperatively, there were statistically significant differences in uncorrected distance visual acuity, corrected distance visual acuity, refractive sphere, cylinder, and spherical equivalent (SE) as compared to baseline. At 3-months postoperatively in Group A, SE showed good stability within ± 0.50 diopter (D) in 22 eyes (88%) and within ± 0.75 D in 23 eyes (92%), while two eyes had an SE beyond 1.00 D emmetropia. Five eyes had amblyopia with minimal improvement in two eyes in Group A after LASIK, and no improvement in three eyes treated with spectacles in Group B. Two amblyopic eyes had developed ocular deviations by the end of the study that referred to the strabismus unit.
Conclusions: Our outcomes revealed that LASIK was more effective and advantageous than spectacles in the treatment of different types of anisometropia in adults. However, future randomized trials should focus on optical versus surgical treatment of anisometropia and anisometropic amblyopia in both pediatric and adult patients, to verify these conclusions before generalizing this treatment modality.