bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Emperor Penguin Optimization and Particle Swarm Optimization Control algorithm for PV with ZSI in Grid Connected System
Authors: M Vidhya , R Senthil Kumar 
Published: April 2021

Abstract
In the paper, a distributed controller for the analysis of SEPIC and Z-Source Inverter (ZSI) based grid-connected Photovoltaic (PV) system. The PV systems are modeled, designed and implemented to given maximum power output with the help of proposed controller. In the paper, a distributed controller is designed to provide maximum output power and to working by changing irradiance and providing various range of active power. An enhanced controller is specified as the Fractional Order PID (FOPID) controller with aid of hybrid approach. The hybrid approach is consisting of Emperor Penguin Optimization (EPO) and Particle Swarm Optimization (PSO). FOPID controller is the advanced PID controller and it gives a better output and robustness than the traditional PID controller. To enhance the performance of the FOPID, the gain parameters are optimized with the utilization of hybrid approach. For achieving the optimal power management and maximum power tracking, the objective function is defined and specified their constraints also. Here, two various methods have been deliberated to changing the inverter operation with constant irradiance and varied irradiance. The proposed method is tested by using MATLAB/Simulink and it is contrasted with the previously developed methods like base model, Ant Colony Optimization (ACO) and PSO algorithm.
Hydrothermal Assisted Synthesis and Biological Evaluation of Biogenic Silver Nanoparticles
Authors: Ekennia Anthony , Uduagwu Dickson N. , Nwaji Njemuwa N. , Olowu Olawale J. , Nwanji Obianuju L. , Udu David Agwu , Christopher Sonde U. , Oje Obinna O. , Andrew Tyopine A. , Inya Joseph E. , Nwosa Chidimma 
Published: April 2021

Abstract
We report on hydrothermal synthesis of biogenic silver nanoparticles (AgNPs) using aqueous leaf extract of Alchornea laxiflora for threefold applications in antibacterial screening against Escherichia coli and Staphylococcus aureus, tyrosinase inhibition of mushroom tyrosine enzymes with 3,4-dihydroxyphenylalanine as a substrate and photocatalytic degradation of malachite green dye. The mode of action for the tyrosinase application and kinetics of both the tyrosinase and photocatalytic activities were provided. The localized surface resonance bands of the AgNPs were observed within the range of 424 – 435 nm from the electronic spectral analysis. Fourier transform-infrared studies reveal the functional groups of plant metabolites such as phenolic compounds and amines on the nanoparticles. The Energy Dispersive X-ray result reveals the presence of silver and other elemental compositions from the plant extract. X-ray diffraction result showed a face-centred cubic crystalline structure for the AgNPs. The SEM analyses reveal that the nanoparticles are spherical in shape with average size range of 20-52 nm. The AgNPs exhibited a dose dependent tyrosinase inhibition activity with IC50 of 20.83 µg/ml and a competitive mode of inhibition. The results of photocatalytic degradation of malachite green dye depicted rapid photo inspired degradation of 86 % in less than a min and at reaction rate of 0.136 min-1. The silver nanoparticles showed enhanced antibacterial activities compared to the precursors: silver nitrate and aqueous extract of Alchornea laxiflora.
Application of Response Surface Methodology for Optimization of Mushroom Saccharification using Crude Enzymatic Extract from Solid-State Fermentation of Pineapple Peels by Aspergillus niger KWM
Authors: Ojwang Daniel Otieno , Jakim Mulaa F. , Obiero George , Midiwo Jacob 
Published: April 2021

Abstract
Mushrooms are a rich source of high value compounds. Efficient enzymatic degradation of mushroom cell-wall matrix is therefore critical in the recovery of cellular components in high yields. In the present study, the effect of reaction variables on mushroom saccharification using crude enzymatic extract was evaluated and optimized using the central composite design based on the response surface methodology. The crude extract displayed CMCase, Fpase and xylanase activities of 1.23Umg− 1 protein, 0.95Umg− 1 protein and 1.52 Umg− 1 protein. The model was validated by the analysis of variance with a coefficient of determination of 0.866 and F test value of 7.39, making the model valid at the 95 % confidence limit. The model achieved glucose yield of 1.490mg/mL at pH 6.5, temperature 50oC, enzyme load of 5% (v/v) and reaction time of 12h. The experiment using optimal model conditions yielded 1.582 mg/mL glucose which is 1.1 folds higher than the predicted model value. This study demonstrated potential of crude extract from solid-state fermentation of low-cost pineapple peels in mushroom processing.
High-performance perovskite solar cells obtained by hybridizing SnS quantum dots with CH3NH3PbI3
Authors: Zhou Liya , Zhong Xiaoying , Fan Hua , Lu Jiangying , Ou Yingjun 
Published: April 2021

Abstract
In this work, SnS quantum dot (QDs) were added into the CH3NH3PbI3 (MAPI) perovskite precursor solution to fabricate MAPI/SnS QDs films with preferred (110) orientation and a perovskite film with large crystal size. This hybrid material showed increased light harvesting ability and a red shift with respect to the number of SnS QDs. As a result, an enhanced performance was achieved in the perovskite solar cells (PSCs) based on MAPI/SnS QDs prepared from the S5, exhibiting a maximum photoelectric conversion efficiency (PCE) of 10.15%, an open-circuit voltage (Voc) of 1.41 V and a fill factor (FF) of 65%.
Nutritional problems of patients infected with COVID-19 and potential for nutritional management of disorders
Authors: Pilat T. L. , Alekseenko S. N. , Krutova V. A. , Akimov M. Yu. , Radysh I. V. , Umnova T. N. , Istomin A. V. , Gordeeva E. A. , Korosteleva M. M. , Khanferyan R. A. 
Published: April 2021

Introduction. One of the most significant issues that require close attention in the treatment and rehabilitation of patients with coronovirus infection is the analysis of the nutritional status of patients and the development of approaches to nutritional support for patients.Aim of study. Analysis of nutritional status of patients infected with COVID-19 and studying the effectiveness of specialized products dietary therapeutic and preventive nutrition during illness and recovery period.Materials and methods. A survey of 283 patients with mild and moderate severity was conducted. The survey showed a significant change in eating behavior in patients during the disease. To assess the effectiveness of nutritional support during the disease and during the recovery period, 36 individuals took a specialized product of dietary therapeutic and preventive nutrition “Detoxifying Kissel” LEOVIT DETOX daily after the diagnosis of COVID-19, both throughout the entire period of the disease, and within 2 weeks after the disease and going to work.Results and discussion. The survey showed the presence of a significant range of eating disorders in patients with coronavirus disease. It was found that in 90% of the respondents during the day, the main meal was 3 or more times. During the disease, the number of main meals decreased in 40% of individuals, and only in 4% of patients this figure increased. When using nutritional support with dietary therapeutic and prophylactic foods during the disease, patients noted a significant decrease in weakness and fatigue, temperature fluctuations, fears, anxiety, suspiciousness and other symptoms began to disappear. The continuation of the intake in the post-ovoid period of the use of nutritional support with the dietary therapeutic and preventive food product “Detoxifying Kissel” LEOVIT DETOX, contributes to a faster recovery of patients.Conclusion. The use of the dietary therapeutic and preventive food product “Detoxifying Kissel” LEOVIT DETOX is an effective method of nutritional support both during the disease and in the post-ovoid period. Long-term use of detoxification products (at least 3–6 months) after the disease is recommended.
To the health of the nation through multi-level educational programs for the population in the field of optimal nutrition
Authors: Pogozheva A. V. 
Published: April 2021

Introduction. Healthy nutrition is the most important component of the quality of life, which is understood as an integral indicator of the mental, physical and social functioning of a person. However, the diet of Russians is not enough vegetables and fruits, dairy products, excess sugar, salt, products containing animal fat and trans fats. Violations of the structure of nutrition, nutritional status lead to the development of alimentary-dependent diseases, primarily cardiovascular, and in particular, arterial hypertension.Goal. Study of alimentary risk factors for arterial hypertension.Materials and methods. The data of the survey of VTSIOM and the company Gideon Richter “Food habits of Russians”, September 2020”, conducted by telephone survey in at least 80 regions (1,600 respondents over 18 years old), are analyzed.Results and discussion. The diet of the adult population of Russia is characterized by a high consumption of animal fat (frequent consumption of fatty dairy products-52% of respondents, butter-61%, sausage products-48%), salt (pickles and marinades – 42%), added sugar (confectionery – 47%) with a lack of fruit, fish and seafood. 23% of respondents add salt to ready meals, and 43% use frying when cooking. Arterial hypertension was noted in 52% of respondents, who, compared to normotonics, less often (32-39%) include in their diet foods that are sources of potassium and magnesium (apricots, bananas, dried fruits, nuts, seeds, etc.), and more often-pickles, marinades (47%) and mayonnaise (45%), containing a large amount of salt, as well as add salt to ready meals (24%).Conclusions. In order to prevent arterial hypertension in Russians, it is necessary to increase their intake of potassium and magnesium, limit the content of table salt in the diet, which will be facilitated by the widespread introduction of educational programs on healthy nutrition.
Latent iron deficiency and iron deficiency anemia in pregnancy: effects on maternal and fetal health, possible ways to solve the problem
Authors: Magomedova A. P. , Lomova N. A. , Karapetyan T. Eh. , Amiraslanov E. Yu. 
Published: April 2021

Iron deficiency with or without anemia in pregnant women is quite common today. In fact, anemia affects nearly 30% of women of reproductive age, and its prevalence among pregnant women is estimated to be 38% worldwide. Although iron deficiency (IR) is not the only cause of anemia, it is the most prevalent one. Anemia-reduction strategies among pregnant women are often ineffective, and severe anemia can greatly increase the risk of maternal mortality, as reported by WHO. Now therefore, the current guidelines for screening and treatment of ID-anemia (IDA) in pregnant women and new-borns require change. Severe anemia can greatly increase the risk of maternal death and adversely affect a developing fetus and new-born. In this review, we analyse the available data on the epidemiology and the effects of iron deficiency on mothers and infants, current treatment strategies and screening recommendations, as well as examine the treatment of IDA in pregnant women and newborns and the problem of poor compliance in patients with latent iron deficiency. A continuous long-term course of administration of oral iron supplements is one of the components of success in the treatment of IDA, and particularly latent forms of iron deficiency in pregnant women. It is often the case that poor patients’ compliance with therapy leads to poor treatment outcomes and misleading conclusions about the ineffectiveness of oral iron dosage forms in the battle against IDA. The data we have analysed suggest the possibility of increasing compliance with IDA treatment in pregnant women.
Application of MCLP and LINGO methods to optimal design of groundwater monitoring network in an oil refinery site
Authors: Vaezihir Abdorreza , Safari Fatemeh , Tabarmayeh Mehri , Khalafi Ali Asghar 
Published: April 2021

Abstract
Groundwater-monitoring network is a set of boreholes (wells) that is used to monitor the water table fluctuation and to detect groundwater contamination. In this research, the maximal covering location problem (MCLP) method is employed to discretize the area, and the LINGO modeling program is used to optimize the number of boreholes. Tabriz oil refinery at the northwest of Iran with high pollution potential that imposes a serious threat to the beneath multilayered aquifer was chosen to evaluate the feasibility of these techniques in field scale. The location and content of storage tanks, leakage history, groundwater flow direction, contaminated well location and the facilities leakage potential are considered as the weighting factors to calculate the number and location of the optimal wells. As a result of optimization, the initial estimated number of boreholes by the MCLP model for the study area is reduced from 349 to 184. A high density of optimal boreholes is allocated to refining zone and oil storing yard, especially near tanks containing dangerous substances due to their toxicity and potential for contaminating water. A vulnerability zoning map prepared using the analytical hierarchy process method indicates a suitable conformation between locations of the boreholes and the vulnerable areas.
SARS-CoV-2 Entry Inhibitors Targeting Virus-ACE2 or Virus-TMPRSS2
Interactions
Authors: Lin Hao , Cherukupalli Srinivasulu , Feng Da , Gao Shenghua , Kang Dongwei , Zhan Peng , Liu Xinyong 
Published: April 2021

Abstract:
COVID-19 is an infectious disease caused by SARS-CoV-2. The life cycle of
SARS-CoV-2 includes the entry into the target cells, replicase translation, replicating and
transcribing genomes, translating structural proteins, assembling and releasing new virions.
Entering host cells is a crucial stage in the early life cycle of the virus, and blocking
this stage can effectively prevent virus infection. SARS enters the target cells mediated
by the interaction between the viral S protein and the target cell surface receptor angiotensin-
converting enzyme 2 (ACE2), as well as the cleavage effect of a type-II transmembrane
serine protease (TMPRSS2) on the S protein. Therefore, the ACE2 receptor
and TMPRSS2 are important targets for SARS-CoV-2 entry inhibitors. Herein, we provide
a concise report/information on drugs with potential therapeutic value targeting
virus-ACE2 or virus-TMPRSS2 interactions to provide a reference for the design and discovery
of potential entry inhibitors against SARS-CoV-2.
Baru Nut Intake and Resistance Training Practice have Potential to Reduce the Cardiometabolic Risk Factors in Type 2 Diabetes
Authors: da Silva John Sebastião Cardoso , Silva Maria Sebastiana , Naves Maria Margareth Veloso 
Published: April 2021

Background:
Type 2 diabetes mellitus (T2DM) is a disease associated with several
cardiometabolic risk factors (CMRF). There is strong evidence about the benefits of oilseeds intake
and the practice of resistance training (RT) in the prevention and treatment of T2DM and its
associated CMRF. However, no study has evaluated the combination of these interventions yet.
Baru nut, an oilseed native to the Brazilian Cerrado, stands out among oilseeds due to its healthy
nutritional composition, which has the potential to reduce CMRF in T2DM. RT, in turn, provides
positive changes in the composition and metabolism of muscle cells, which contributes to improving
cardiometabolic health.

Objective:
This review aimed to summarize the effects and mechanisms related to the intake of
baru nut and the practice of RT in reducing CMRF in T2DM.

Methods:
Literature research was performed using the keywords “type 2 diabetes mellitus”,
“Dipteryx alata Vog”, “nuts”, “physical exercise” and “resistance training”, isolated or associated,
in Web of Science and Pubmed databases.

Results:
Baru nut is oilseed with a high density of nutrients and bioactive compounds with antioxidant
and antihypercholesterolemic properties, and the RT is associated with beneficial effects
on CMRF of individuals with T2DM. Thus, the consumption of baru nut and the RT have the potential
to improve insulin sensitivity, glycemic control, body composition, and serum lipid profile.

Conclusion:
The baru nut consumption and the RT have the potential to reduce the cardiometabolic
risk factors in T2DM. Both interventions are innovative and promising approaches to preserve
the health of individuals with T2DM.
Retinoprotective Effects Of Crocin And Crocetin via Anti-Angiogenic Mechanism in High Glucose-Induced Human Retinal Pigment Epithelium Cells
Authors: Sepahi Samaneh , Soheili Zahra-Soheila , Tavakkol-Afshari Jalil , Mehri Soghra , Hosseini Seyedeh M. , Mohajeri Seyed A. , Khodaverdi Elham 
Published: April 2021

Background:
Diabetic retinopathy (DR) is one of the most common side effects of diabetes. We aimed to investigate the effects of crocin and crocetin (as a deglycosylated form of crocin in blood stream) in gene expression or protein levels of vascular endothelial growth factor (VEGF), vascular endothelial growth factor-receptor1 (VEGFR-1), matrix metalloproteinases2 (MMP-2), matrix metalloproteinases9 (MMP-9) and thrombospondin-2 (TSP-2) in high glucose cell culture media.

Methods:
The retinal pigment epithelium (RPE) cells were exposed to high glucose (HG, 30 mM glucose concentration) and normal glucose (NG, 24.5 mM mannitol + 5.5 mM glucose) for six days. RPE cells were treated in four treatment groups (crocin, crocetin, Bevacizumab, and crocin + Bevacizumab). Gene expressions were measured using quantitative real-time PCR, and proteins level was evaluated by western blot.

Results:
Findings showed that VEGF gene expression and protein level significantly decreased in all treatment groups. In addition, reduction in VEGFR1 gene expression was significantly higher in Bevacizumab and crocin + Bevacizumab groups than other groups. Only, crocin and crocetin could reduce the gene levels of MMP-2 and MMP-9. In addition, TSP-2 protein levels increased when HG cells were exposed crocin or crocin + Bevacizumab groups.

Conclusion:
Our data showed that crocin and crocetin have anti-VEGF function similar to Bevacizumab, act as an anti-angiogenic agent. Also, crocin and crocetin could decrease MMP-2 and MMP-9 gene levels, as inflammatory and angiogenesis factors. As a result, crocin and crocetin have protective effects against angiogenesis and inflammation in DR.
Coenzyme Q10 Supplement Rescues Postovulatory Oocyte Aging by
Regulating SIRT4 Expression
Authors: Su Jianmin , Xing Xupeng , Zhang Jinjing , Zhang Jingcheng , Wang Yongsheng , Wang Jingyi , Kang Jian , Quan Fusheng , Zhang Yong 
Published: April 2021

Background:
High-quality of the oocyte is crucial for embryo development and the success
of human-assisted reproduction. The postovulatory aged oocytes lose developmental competence
with mitochondrial dysfunction and oxidative stress. Coenzyme Q10 (CoQ10) is widely distributed
in the membranes of cells and has an important role in the mitochondrial respiration chain
against oxidative stress and modulation of gene expression.

Objective:
The objective of this study is to investigate the functions and mechanisms of CoQ10 on
delaying postovulatory oocyte aging.

Methods:
Quantitative real-time PCR and Immunofluorescence staining were used to determine
the expression patterns of the biogenesis genes of CoQ10 in postovulatory aged oocytes compared
with fresh oocytes. The mitochondrial function, apoptosis, reactive oxygen species (ROS) accumulation
and spindle abnormalities were investigated after treatment with 10 μM CoQ10 in aged
groups. SIRT4 siRNA or capped RNA was injected into oocytes to investigate the function of
SIRT4 on postovulatory oocyte aging and the relationship between CoQ10 and SIRT4.

Results:
Multiple CoQ10 biosynthesis enzymes are insufficient, and a supplement of CoQ10 can
improve oocyte quality and elevate the development competency of postovulatory aged oocytes.
CoQ10 can attenuate the aging-induced abnormalities, including mitochondrial dysfunction, ROS
accumulation, spindle abnormalities, and apoptosis in postovulatory aged oocytes. Furthermore,
SIRT4, which was first found to be up-regulated in postovulatory aged oocytes, decreased following
CoQ10 treatment. Finally, knockdown of SIRT4 can rescue aging-induced dysfunction of mitochondria,
and the efficiency of CoQ10 rescuing dysfunction of mitochondria can be weakened by
SIRT4 overexpression.

Conclusion:
Supplement of CoQ10 protects oocytes from postovulatory aging by inhibiting SIRT4
increase.
COVID-19
Authors:   CASIS Vancouver
Published: April 2021

On July 16th, 2020, the Canadian Association for Security and Intelligence Studies (CASIS) Vancouver hosted its third digital roundtable event of the year, COVID-19: China’s Foreign Policy in the South China Sea. The presentation was conducted by guest speaker Mr. Brett Witthoeft, senior analyst in N39 International Engagement, at Maritime Forces Pacific (MARPAC) HQ at CFB Esquimalt, Canada’s west coast naval formation. Mr. Witthoeft’s presentation gave an overview of the South China Sea (SCS) and its importance as well as how this fits into the larger picture to the rest of the world. Subsequently, Mr. Witthoeft answered questions submitted by the audience, which focused on the ramifications of the SCS conflicts.
APA Citation
CASIS Vancouver. (2020). COVID-19: China’s foreign policy in the South China Sea. The Journal of Intelligence, Conflict, and Warfare, 3(2), 54-60. https://journals.lib.sfu.ca/index.php/jicw/article/view/2408/1817.
The Protective Power of Behavioural Threat Assessment (& Management) (BTAM)
Authors:   CASIS Vancouver
Published: April 2021

On August 20th, 2020, the Canadian Association for Security and Intelligence Studies (CASIS) Vancouver hosted its fourth digital roundtable event of the year, The Protective Power of Behavioural Threat Assessment (& Management) (BTAM). The presentation was conducted by guest speaker Andrea Ringrose, Director of Campus Public Safety at Simon Fraser University, who is also on the Board of Directors at Canadian Association of Threat Assessment Professionals. Ringrose’s presentation gave an overview on behavioural threat assessment and management, and how public safety and caring for persons of concern are interconnected when assessing threats and risks. Subsequently, Ringrose answered questions submitted by the audience, which focused on the assessment of different offender types, the handling bias during the BTAM process, the role of artificial intelligence, and the possibility of echo chambers accelerating behaviour.
APA Citation
CASIS Vancouver. (2020). The protective power of behavioural threat assessment (& management) (BTAM). The Journal of Intelligence, Conflict, and Warfare, 3(2), 77-83. https://journals.lib.sfu.ca/index.php/jicw/article/view/2409/1816.