bluuebunny/crossref_metadata_2025_split huggingface dataset:
Active Pyridinium Based Ionic Liquid Anchored Quinuclidine Organocatalyst
for Morita-Baylis-Hillman Reaction
Authors: Srivastava Vivek 
Published: November 2021

:
In the present manuscript, we easily synthesized three different types of ionic liquid
supported 3-quinuclidinone organocatalysts such as [PyAmEQ][BF4] (Py-CATALYST-1),
[PyAmEQ][PF6] (Py-CATALYST-2), and [PyAmEQ][NTf2] (Py-CATALYST-3). After performing
the careful characterization of the above catalysts with sophisticated analytical techniques, we
utilized them as a catalyst to study the passive Morita-Baylis-Hillman reaction. The corresponding
Morita-Baylis-Hillman adducts were easily isolated, followed by the simple ether extraction method.
Moreover, the above protocol also promoted low catalyst loading, short reaction time, wide
substrate scope, easy product, and catalyst recycling. We easily recycled the catalytic system for 5
runs with no noticeable loss in the chemical yield. Additionally, Py-CATALYST-3 was also used to
prepare biologically active materials, i.e., N-((E,3S,4R)-5-benzylidene-tetrahydro-4-hydroxy-6-oxo-
2H-pyran-3-yl) palmitamide derivatives.
Prevalence of Anti-nuclear and Anti-phospholipid Antibodies in an Egyptian
Cohort with Schizophrenia: A Case-control Study
Authors: Medhat Basma M. , Abu-Zaid Mohammed H. , Dorgham Dalia , El-Ghobashy Nehal , Afifi Angie Y. , El-Makawi Shirin , Ayoub Doaa R. , Khalaf Ola O. , Amer Reham , Koptan Dina M.T. , Maged Lobna A. 
Published: November 2021

Background:
Psychiatric disorders, including schizophrenia, could herald other manifestation(
s) of systemic lupus erythematosus (SLE) potentially hindering timely and optimal management.
Moreover, schizophrenia is among the described ‘extra-criteria’ manifestations of anti-phospholipid
syndrome (APS). Hence, screening schizophrenia patients for SLE and APS may pose diagnostic
and therapeutic implications.

Objectives:
Examine schizophrenia patients with no overt connective tissue disease(s) manifestation(
s) for clinical and/or serologic evidence of SLE and/or APS.

Methods:
The study included 92 schizophrenia patients (61 (66.3%) males) and 100 age- and gender-
matched healthy controls. Both groups were tested for anti-nuclear antibodies (ANAs), antidouble
stranded deoxyribonucleic acid (anti-dsDNA) antibodies, complement 3 (C3) and C4, and
criteria anti-phospholipid antibodies (aPL) (anticardiolipin Immunoglobulin (Ig) G and IgM, antibeta-
2-glycoprotein I IgG and IgM, and lupus anticoagulant (LAC)).

Results:
The patients’ mean age and disease duration were 28.8 ± 8.1 and 5.7 ± 2.2 years, respectively.
The prevalence of ANA positivity, height of titre, and pattern was comparable between patients
and controls (p = 0.9, p = 0.8 and p = 0.1, respectively). Anti-dsDNA antibodies and hypocomplementemia
were absent in both groups. A significantly higher frequency of positive LAC
was observed among patients compared with controls (7.6% vs. 1%, p = 0.02), whereas other aPL
were comparable between both groups. None of the patients or controls demonstrated clinically
meaningful (medium or high) aPL titres.

Conclusion:
In our study, schizophrenia was solely associated with LAC. Thus, in the absence of
findings suggestive of SLE or APS, routine screening for both diseases is questionable.
Type 2 Diabetes Mellitus and Alzheimer's Disease: A Review of the Potential
Links
Authors: Yaghoobpoor Shirin , Deravi Niloofar , Pakdin Majid , Toutounchian Samaneh , Namazi Sina , Arabpour Zahra , Pouladi Amirreza , Afsahi Sahar , Poudineh Mohadeseh , Nasab Mohammad Mehdi Mousavi 
Published: November 2021

:
Diabetes mellitus and Alzheimer’s disease are considered the most prevalent diseases in
older ages worldwide. The main pathology of Alzheimer’s disease is highly related with accumulation
of misfolded proteins that lead to neuronal dysfunction in the brain. On the other hand, diabetes
mellitus is associated with alteration of insulin signaling, which could cause the reduction of
glucose uptake, metabolic prohibition of energy consuming cells, as well as suppression of glucose
to fat conversion in the liver. In spite of having seemingly different pathological features, both diseases
share common underlying biological mechanisms. Besides, the epidemiological and environmental
links between these two diseases should not be overlooked. In this study, we aim to review
shared pathological mechanisms of Alzheimer’s disease and diabetes mellitus, including impaired
glucose metabolism, increased Amyloid-Beta (Aβ) production, impaired lipid metabolism, mitochondrial
dysfunction, increased inflammation and elevated oxidative stress. Furthermore, we discuss
epidemiological association between these two diseases and also review animal investigations,
which have evaluated the potential links between the two diseases.
Solitary Fibrous Tumor of the Great Omentum: A Case Report and Literature Review
Authors: Geng Chengjun , Yin Huikang , Ye Daixi , Zhu Yechen 
Published: November 2021

Background:
We report a case of a 23-year-old man with a solitary fibrous tumor of the
great omentum who presented clinically as a case of dull abdominal pain.

Case Presentation:
Solitary fibrous tumor normally occurs in the visceral pleura. Extrathoracic solitary
fibrous tumor is rare, especially those from the great omentum, with approximately 31 cases
reported in the literature.

Conclusion:
After reviewing and summarizing the imaging findings of 31 cases of solitary fibrous
tumor of the greater omentum, we considered that the characteristic findings can provide a reliable
basis for preoperative diagnosis.
The Value of 99mTc-MIBI SPECT/CT in the Postoperative Assessment of Patients with Differentiated Thyroid Carcinoma
Authors: Seven Bedri , Okudan Berna , Gülaldı Nedim C.M. , Çapraz Mustafa , Açıkgöz Yusuf 
Published: November 2021

Background:
The therapeutic approaches of differentiated thyroid carcinoma (DTC) are
surgery, ablation therapy with the postoperative use of radioiodine-131 (131I), and thyroid-stimulating
hormone (TSH) suppression therapy. After the surgical therapy, the patient should be assessed
for remnants/metastases.

Objective:
The purpose of this research was to investigate the role of technetium-99m-methoxyisobutylisonitrile
(99mTc-MIBI) single photon emission computed tomography/computed tomography
(SPECT/CT) in the postoperative management of patients with DTC.

Methods:
The study comprised 22 DTC patients (13 women, 9 men; mean age 46.55 ± 13.27 y)
who underwent a total thyroidectomy previously. All patients were investigated for thyroid remnants/
metastases by 99mTc-MIBI SPECT/CT, posttherapy 131I whole-body scan (WBS) and ultrasound
(US). Serum TSH, thyroglobulin and anti-Tg antibody levels were measured. Results of
imaging modalities and laboratory measurements were compared with each other.

Results:
99mTc-MIBI SPECT/CT, 131I WBS and US respectively demonstrated thyroid remnants in
15 (68.18%), 22 (100%) and 14 (63.63%) of all patients and metastatic lymph nodes in 8 (100%), 6
(75%) and 6 (75%) of the 8 patients with lymph node metastases. 99mTc-MIBI SPECT/CT also demonstrated
lung metastases in 2 patients (9.09% of all patients). The same result was obtained with
131I WBS.

Conclusion:
The findings of this study show that 99mTc-MIBI SPECT/CT can be effective for detecting
metastases in patients with DTC who underwent surgery prior to 131I therapy.
Electrical and Structural Properties of HDPE/MWCNT/PE-g-MAH Nanocomposites Prepared Using Solution Mixing and Hot Compaction Two-step Approach
Authors: Al-Hussein Mahmoud , Jaffal Ali , Abu-Zuryak Rund 
Published: November 2021

Background:MWCNTs tend to form agglomerates in nonpolar polymers due to their small size and large surface area. A promising approach to facilitate their dispersion within the polymeric matrix is based on employing a compatibilizer agent.Objective:The current study aimed to investigate the effect of a compatibilizer agent based on maleic anhydride grafted HDPE (PE-g-MAH) on the electrical and morphological properties of highdensity polyethylene/multi-wall carbon nanotubes nanocomposites (HDPE/MWCNT/PE-g-MAH) prepared by solution mixing and hot compaction two-step approach.Methods:A two-step approach based on solvent mixing and hot compaction was used to prepare nanocomposites of HDPE/MWCNT/PE-g-MAH with different MWCNTs and PE-g-MAH contents. The electrical, morphological, and HDPE crystalline structure properties of the nanocomposites were characterized by impedance spectroscopy, high-resolution field emission scanning electron microscopy, and X-ray diffraction, respectively.Results:The results confirm the positive role of the PE-g-MAH compatibilizer in enhancing the dispersion of the MWCNTs and, in turn, the formation of more conductive pathways at low MWCNTs content in the nanocomposites. Adding 2 wt% of the compatibilizer to the nanocomposite of 1 wt% MWCNTs increases the electrical conductivity by more than three orders of magnitude. Increasing the MWCNTs concentration by more than 1 wt% leads to a limited enhancement in conductivity of the nanocomposite prepared using 2 wt% of PE-g-MAH compatibilizer. Meanwhile, the morphological characterization revealed that the limited increase in conductivity of nanocomposites with only 1 wt% compatibilizer is related to a substantial increase in the HDPE crystallinity (from 14.8 to 43.9%) induced by the enhanced nucleating effect of the dispersed MWCNTs. The excess HDPE crystalline regions suppress the formation of effective MWCNTs conducting pathways due to their confinement into smaller inter-crystallite regions in the nanocomposite.Conclusion:Therefore, a balanced role of the compatibilizer between the dispersion of the MWCNTs and the nucleation of more HDPE crystallites has to be achieved by carefully selecting the compatibilizer type and concentration.
Eating Disorders and Type 1 Diabetes: A Perspective
Authors: Marucci Simonetta , De Iaco Giulia , Lisco Giuseppe , Mariano Francesco , Giagulli Vito Angelo , Guastamacchia Edoardo , De Pergola Giovanni , Triggiani Vincenzo 
Published: November 2021

:
Patients with type 1 diabetes (T1D) are at risk of clinical eating disorders (EDs) and disordered eating behaviors (DEBs) than the general population. This burden is related mainly to diabetes-related physical and psychosocial issues especially beginning during childhood. DEBs must be investigated carefully and promptly managed in case of suspicion, as they can evolve into severe clinical EDs over time and are strictly related to poor outcomes.
The significant number of scientific articles dealing with the relationship between T1D and DEBs or EDs confirms the complexity of these problems and the difficulties in diagnosis and treatment.
This paper examined current scientific literature related to this topic, emphasizing the epidemiological and clinical complexity of the phenomenon and briefly summarizing EDBs management strategy in T1D patients.
Nigella Sativa (Black seeds) – Potential Herb to Help Weight Loss
Authors: Maideen Naina Mohamed Pakkir 
Published: November 2021

:
Obesity is associated with many diseases, including diabetes, hypertension, dyslipidemia,
coronary heart disease, stroke, fatty liver disease, cancer, osteoarthritis and many others.
The prevalence of obesity is increasing every year among the global population. The persons being
overweight or obese may consider traditional herbal medicines as a good strategy to manage chronic
conditions due to various reasons. Nigella sativa (Black seeds) has been used to treat various conditions,
including obesity, diabetes, hypertension, cancer, etc. Hence, the anti-obesity potential of
N. sativa is analyzed in this review. The databases, including Medline/PMC/PubMed, Google Scholar,
Science Direct, and reference lists, were searched to identify relevant randomized controlled
clinical trials. Significant reduction of body weight, body mass index and waist circumference have
been observed in many randomized controlled clinical trials (RCTs) by using N. sativa. Hence, the
individuals willing to reduce their body weight can effectively use N. sativa along with lifestyle
modifications.
Primer registro de Acanthoscelides obtectus (Coleoptera: Chrysomelidae: Bruchinae) en Senna multiglandulosa (Fabaceae) de la región andina central del Perú
Authors: Baltazar Castañeda Hernán , Baltazar Sedano Danilo , Baltazar Sedano Neddy , Álvarez Tolentino Daniel 
Published: November 2021

Acanthoscelides obtectus (Say, 1831) (Coleoptera: Chrysomelidae: Bruchinae) es unescarabajo de distribución cosmopolita que ocasiona graves daños a diversas especies de la familia Fabaceae. Este trabajo es el primer reporte de su infestación en arbustos de Senna multiglandulosa (Jacq.) H.S. Irwin & Barneby, 1982 (Fabaceae) en la zona andina central del Perú. Se describe la morfología de los estados biológicos de A. obtectus y las perforaciones que realizaron en legumbres infestadas colectadas en tres lugares del Valle del Mantaro de enero a diciembre 2018. Se midió la longitud total (L) y ancho (A) de los huevos, larvas, pupas y adultos de A. obtectus, así como el diámetro (D) de las perforaciones en vainas y semilla de S. multiglandulosa. Los resultados mostraron diferencias significativas en los tamaños de cada uno de los estadios (p < 0,001) y sus perforaciones en las legumbres (p < 0,001), afectan especialmente las semillas de S. multiglandulosa, por lo cual se constituye en un problema sanitario muy severo en la planta estudiada.
Acanthoscelides obtectus (Say, 1831) (Coleoptera: Chrysomelidae: Bruchinae) is a beetle with a cosmopolitan distribution that causes severe damages to diverse species of the Fabaceae family. This is the first report of its infestation on Senna multiglandulosa (Jacq.) H.S. Irwin & Barneby, 1982 (Fabaceae) bushes in the central Andean region of Peru. The morphology of the biological stages of A. obtectus and the perforations they made on infested legumes collected in three sites of Mantaro Valley from January to December 2018 are described. The total length (L) and width (W) of eggs, larvae, pupae, and adults of A. obtectus and the diameter (D) of the perforations on the pods and seeds of S. multiglandulosa were measured. The results showed significant differences in the size of each stage (p < 0.001) and their perforations on legumes (p < 0.001), affecting mainly the seeds of S. multiglandulosa, constituting a severe health problem for the studied plant.
Appointment of the Constitutional Court Justice: Some Issues
Authors: Rodiņa Anita 
Published: November 2021

This article analyses important issues brought up in public regarding one of the constitutional institutions – formation of the Constitutional Court. At the outset, the article looks at the models of accessing the position of the Constitutional Court justice, their weaknesses and also responsibility of persons engaged in the appointment of justices. Challenges of parliamentary procedures are also discussed, especially considering that the platform e-Saeima was used as the voting platform to appoint the justice. The article also reflects a debate on whether a Constitutional Court justice can be appointed only once in a lifetime, keeping in mind the recent amendments to the Constitutional Court Law, including reappointment mechanism if the judge has had to leave the position before expiration of 10 years’ mandate. Finally, the article analyses the role and meaning of decisions made by a special institution – Judicial Council – when appointing the Constitutional Court justice.
Antitrust Rules and Competition Violations. The Evolution of Consumer Protection
Authors: Capasso Antonio 
Published: November 2021

According to the order of the Court of Verona of 01.10.2018, No. 3763, a prohibited agreement pursuant to Art. 2, Law No. 287/1990, can also be harmful to consumer or entrepreneur, who has not taken part in it. In order to recognize an interest in invoking the protection referred to in Art. 33, para. 2, Law No. 287/1990, it is not sufficient to allege the nullity of the agreement itself but it is also necessary to specify the consequence that this failure has produced regarding the right to an effective choice between a plurality of competing products. This paper intends to investigate the institutions of the omnibus guarantee and its consequent nullity for violation of the discipline that governs agreements restricting competition. It also provides an analysis of the remedies and safeguards available to consumers who have remained extraneous to the competitive agreement, and who have entered into a subsequent contract of the latter.
Procedural Autonomy of a Member State: Application of the Principle by Latvian Administrative Courts
Authors: Briede Jautrīte 
Published: November 2021

The article addresses certain issues of principle of national procedural autonomy. The meaning of the principle is briefly explained at the beginning of the article. It is followed by analyses of examples of the application of this principle by Latvian courts after the judgments of Court of Justice of the European Union, as well application of the principle of procedural autonomy by Latvian courts on their own initiative.
Apropiacion y accion colectiva: ida y vuelta. El caso de una movilizacion ciudadana parea seguir formando parte del Centro Historico de Mexico
Authors: Vedie Marie 
Published: November 2021

Este artículo pretende revelar la relación ente acción colectiva y apropiación del espacio, utilizando el caso de la movilización de una organización de arrendatarios en el Centro Histórico de México. Bajo el prisma de los conceptos diferenciados por Henri Lefebvre entre espacio dominado y espacio apropiado, el Centro Histórico aparece en primer lugar como un espacio dominado, transformado por el poder. Personifica de manera paradigmática la puesta en escena del espacio del poder político, y también es el objeto desde el principio de los años 2000 de políticas destinadas a normalizar los usos de este espacio y a erradicar a los habitantes más pobres que lo habitan. En este contexto, definiremos las formas de apropiación del espacio de la acción colectiva de los habitantes movilizados para seguir habitando el Centro Histórico. Pondremos de manifiesto que la apropiación es el objetivo y a la vez la condición de la acción colectiva. En esta constante ida y vuelta, los militantes redefinen poco a poco el objeto de su apropiación: el hábitat en el Centro Histórico.
Load Test pada Microservice yang menerapkan CQRS dan Event Sourcing
Authors: Fansha Difa Al , Setyawan Muhammad Yusril Helmi , Fauzan Mohamad Nurkamal 
Published: November 2021

Abstract. Load Test on Microservice implementing CQRS and Event Sourcing. In developing an application, determining the architecture is a very important job. This research implements microservice architecture with CQRS pattern and event sourcing on OpenAPI, API-driven and event-driven integration between services. Applying the right architecture can make the performance of the application faster. There are two test activities that are useful to find out the difference in the frequency of requests for APIdriven and event-driven that can affect response time, error rate and throughput, as well as analyze which architecture has better performance. The test is carried out using a load test technique using the JMeter tool. This study proves that microservices with CQRS and Event Sourcing patterns have 3.7% faster performance compared to API-driven, and communication between services has no effect on error rate and throughput. Keywords: microservice, load test, CQRS, event sourcing, software architecture Abstrak. Dalam pengembangan sebuah aplikasi, penentuan arsitektur merupakan pekerjaan yang sangat penting. Penelitian ini mengimplementasikan arsitektur microservice dengan pola CQRS dan event sourcing pada OpenAPI, integrasi antar service berbasis API-driven dan event-driven. Penerapan arsitektur yang tepat dapat membuat performansi dari aplikasi menjadi lebih cepat. Terdapat dua aktivitas pengujian yang berguna untuk mengetahui perbedaan frekuensi request pada API-driven dan eventdriven yang dapat mempengaruhi response time, error rate dan juga throughput, serta menganalisis arsitektur mana yang memiliki performa yang lebih baik. Pengujian dilakukan dengan teknik load test yang menggunuakan tool JMeter. Penelitian ini membuktikan bahwa microservice dengan pola CQRS dan Event Sourcing memiliki performansi lebih cepat 3,7% dibandingkan dengan API-driven, serta komunikasi antar service tidak berpengaruh pada error rate dan throughput.Kata Kunci: microservice, load Test, CQRS, event sourcing, software arsitektur
Technology and Truth. Reflections on Russia, America, and Live Not By Lies
Authors: Grenier Paul 
Published: November 2021

The main thesis of the author of the essay is that in contemporary Western society the objective and subjective truth is created by the people. This is the key to what the author calls technological and technocratic society for which truth and reason are no longer the goals that the man should be striving for in his thoughts and behavior. In a technocratic society the reality itself is created and thus accordingly the term “lie” loses its meaning. Anything can potentially be viewed as a useful step in the process of creating something new and “efficient” for those who above all value the strengthening of their own control (over people, nature, etc). Subjects acting in the framework of technological society deny any identifications and technologically determine themselves what man, nature and society is, – right down to the basics of our biological existence. This approach overturns such notion as absolute truth, establishing relevant truth. In contemporary Western society subjective and objective truth is created. The author examines in detail how this approach is used by the United States in their international policy to achieve dominance. He also considers Russia to be the only great power that is prepared to choose a different line of development due to its historical development. The possibility of such choice is capable to prevent final Americanization of Europe, which, should it happen, would lead to the “mankind as a whole losing its past”, as Simone Weil predicted.
Post-liberal Communitarianism in Contemporary Russia: Future in the Legacy of the Past
Authors: Bakurkov Anatoly A. , Tyapin Igor N. 
Published: November 2021

The address to communitarianism as a system of ideas and a model of the “ideal type” of a public organization can serve as the foundation for scientific and philosophical research of the problems of organizing public dialogue and social consolidation, the implementation of the organic relationship of technological progress with institutional and anthropological conservatism. The issue of communitarianism has a certain tradition in Russian thought of different eras and directions (Slavophilism, philosophy of the “new religious consciousness”, Eurasianism, ethical and anthropological studies in Soviet – orthodox and non–Marxist – philosophy and certain recent historical, philosophical and political science works), which is both indirect and in some cases quite direct. Comparing the approaches of domestic and foreign authors to the factors of transformation of society on the principles of social harmony allows us to conclude that when in Western philosophy communitarianism is simply the criticism of liberalism and the search for a balance between various social forces interests, in Russia it is capable to reach a fundamentally higher axiological and theoretical level within the framework of integration with the conceptual baggage of the Russian idea and the real experience of the state of social justice understanding.