bluuebunny/crossref_metadata_2025_split huggingface dataset:
О взаимосвязях геометрических параметров оросителя, устойчивости и кратности получаемой пены
Authors: Likhomanov Aleksey O. , Govor Eduard G. , Kamlyuk Andrey N. 
Published: May 2021

Цель. Проанализировать влияние геометрических параметров розеточного оросителя на кратность и устойчивость получаемой воздушно-механической пены. Исследовать взаимосвязь между кратностью и устойчивостью пены низкой кратности, генерируемой в розеточных оросителях, при использовании пенообразователей общего назначения и пенообразователей-смачивателей.
Методы. Общие научные методы исследования (анализ, синтез, систематизация). Исследование взаимосвязи между кратностью и устойчивостью пены выполнялось при проведении экспериментов, а для математического описания установленной зависимости применены методы регрессионного и статистического анализов.
Результаты. Установлены геометрические параметры дужек и розетки оросителя, значения которых влияют на кратность и устойчивость получаемой пены, а также проанализированы оптимальные по кратности и устойчивости пены значения данных параметров. Получено выражение для определения коэффициента рабочей поверхности розетки оросителя, имеющей конусообразную форму. Установлено, что ранее выявленный линейный характер зависимости устойчивости пены от ее кратности для пенообразователя ПО-6РЗ (6 %) характерен и для других пенообразователей: пенообразователя общего назначения Синтек-6НС (6 %) и пенообразователя-смачивателя ОПС-0,4 (1 %).
Область применения исследований. Выражение для определения коэффициента рабочей поверхности розетки Ks может широко использоваться при разработке новых розеточных оросителей для автоматических установок пожаротушения, а также для модернизации их конструкции. Кроме того, с помощью полученного выражения зависимости устойчивости пены от ее кратности и эмпирических коэффициентов пропорциональности данной зависимости для пенообразователей ОПС-0,4 (1 %) и Синтек-6НС (6 %) можно рассчитать значение устойчивости пены, зная ее кратность, или значение кратности, зная устойчивость.
Pengaruh Metode Total Physical Response (TPR) Terhadap Kemampuan Kosakata Bahasa Indonesia pada Anak Usia 5-6 Tahun
Authors: Maulidia Eva Putri , Hasibuan Rachma 
Published: May 2021

Tujuan dari penelitian yang dilaksanakan ialah guna mengetahui pengaruh metode Total Physical Response (TPR) terhadap kemampuan kosakata Bahasa Indonesia pada anak usia 5-6 tahun. Dimana Metode penelitiannya menggunakan pendekatan kuantitatif berjenis Quasi Experimental Design dengan desain penelitiannya Nonequivalent Control Group Design dengan dua kelompok yang digunakan yaitu kelompok eksperimen dan kontrol. Hasil penelitian validitas pretest dan posttest kedua kelompok menunjukkan semua nilai rhitung > rtabel, sehingga semua item pertanyaannya valid. Begitu pula pengujian reliabilitas memperlihatkan nilai Cronbach’s Alpha > rtabel oleh karenanya seluruh indikator dinyatakan reliabel. Dari pengujian normalitas nilai signifikansi data semua variabel < 0,05 sehingga pendistribusian data tidak normal, lalu dipakailah uji statistik Mann-Whitney guna pengujian hipotesisnya. Melalui pengujian Mann Whitney didapat nilai Asymp.Sig (2-tailed) berskor 0,000<nilai probabilitasnya 0,05 sehingga diputuskan menolak H0. Sehingga kesimpulan dalam penelitian ini adalah terdapat pengaruh metode Total Physical Response (TPR) terhadap kemampuan kosakata Bahasa Indonesia pada anak usia 5-6 tahun secara signifikan. Keberhasilan tersebut dikarenakan penerapan metode ini pada kosakata yang dikenalkan ke anak menghasilkan kemampuan anak yang dapat mempraktekkan gerakan sesuai perintah guru, mampu memberikan respon instruksi sederhana sesuai perintah guru, dapat menyebutkan kosakata yang dilihat dari gambar, mampu menunjukkan.
Dampak Pembangunan Destinasi Wisata Mloko Sewu Terhadap Kehidupan Sosial Ekonomi Masyarakat Desa Pupus Kecamatan Ngebel
Authors: Maharani Dhinar Ayu , Hanif Muhammad , Parji Parji 
Published: May 2021

Tujuan penilitian ini untuk menarangkan sejarah pembangunan destinasi wisata Mloko Sewu, pengelolaan destinasi wisata Mloko Sewu, akibat pembangunan destinasi wisata Mloko Sewu terhadap kehidupan sosial ekonomi warga Desa Pupus Kecamatan Ngebel Kabupaten Ponorogo dan akibat pembangunan destinasi wisata Mloko Sewu terhadap kehidupan sosial ekonomi warga Desa Pupus Kecamatan Ngebel Kabupaten Ponorogo serta selaku sumber belajar IPS SMP/ MTs. Penelitian ini menggunakan metode kualitatif bertabiat deskriptif. Informasi yang diperoleh dianalisis dengan metode analisa informasi interaktif model informasi Miles and Huberman. Dalam penelitian ini metode pengumpulan informasi yang digunakan penelitian merupakan wawancara mendalam, observasi serta dokumentasi. Bersumber pada hasil penelitian bisa disimpulkan kalau pembangunan wisata Mloko Sewu berawal dari kemauan buat memperlihatkan sisi eksotisme yang terdapat di Kecamatan Ngebel. Ditemui pula kalau pengelolaan wisata Mloko Sewu seluruhnya dikelola oleh pihak pengelola Mloko Sewu tanpa terdapat sama sekali kedudukan dari pemerintahan Kabupaten Ponorogo. Akibat pembangunan destinasi wisata Mloko Sewu di Desa Pupus untuk warga antara lain pergantian mutu hidup masyarakat, peningkatan kedudukan pengelola Mloko Sewu dalam kehidupan sosial masyarakat, peningkatan pemasukan warga yang membuka usaha di dekat wisata Mloko Sewu, terciptanya peluang kerja dan dapat menimbulkan potensi penyimpangan sosial. Dampak pengembangan kawasan wisata Mloko Sewu terhadap kehidupan sosial ekonomi masyarakat dapat dijadikan sebagai sumber rujukan pembelajaran khususnya untuk tema IPS SMP/MTs kelas VII.
An overview of the quality of life of Knee osteoarthritis patients at the Surakarta Orthopedic Hospital
Authors: Rachmat Nur , Minulyo Aji Janmo , Zubaidi Alfan 
Published: May 2021

ABSTRACT
Background: Osteoarthritis is a chronic degenerative disease of the joints. Functional limitations experienced by people with knee osteoarthritis are related to changes in quality of life. Knee Osteoarthritis needs to be assessed as a whole which includes several domains of quality of life, namely the domains of pain, stiffness and physical function. This study was conducted to determine the correlation between pain intensity and quality of life in patients with knee osteoarthritis.
Methods: a quantitative study using an analytic observational method with a cross-sectional approach. Population of 70 patients, a sample of 33 patients. The research was conducted in October 2020 at the Orthopedic Hospital in Surakarta City, Central Java, Indonesia. Data were collected by direct interviews to assess pain intensity based on the Numeric Rating Scale (NRS) and assess quality of life based on the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) questionnaire. Normality test using Sapiro Wilk because the data is normaly distributed. Hipotesis test using Pearson correlation.
Results: Age range of patients with knee osteoarthritis mostly occurred at the age of 56-60 years, women had a greater frequency of experiencing knee osteoarthritis with a frequency of 78.8%, the most incidence of knee osteoarthritis was experienced by patients with normal BMI, namely 54.5%, The results of the Pearson correlation test showed a significance value of Sig. (2-tailed) is 0.000149 <0.05, which means that there is a significant correlation between the variables between pain and quality of life. Has a positive relationship and strong relationship strength (r = 0.613).
Conclusion: There is a significant correlation between pain intensity and quality of life in patients with osteoarthritis
BREASTFEEDING TEMPORAL DISTRIBUTION TRENDS AMONG NEONATES IN TERTIARY CARE HOSPITAL IN LAHORE
Authors: Hamid Mehmood  , Zarmast Khan  , Abdul Rauf  , Ammara Waqar  
Published: May 2021

ABSTRACT
BACKGROUND & OBJECTIVE: Breastfeeding provides immunity against bacterial, viral, and other infectious diseases. More than four million new neonates die due to vaccine-related diseases in the first 28 days of their lives. It is therefore emphasized that breastfeeding in the first hours after delivery may save the neonate. The objective of this study was to determine the factors affecting the pattern of breastfeeding among the neonates and assess the frequency of early breastfeeding among neonates at Gulab Devi Hospital, Lahore.
METHODOLOGY: It was a cross-sectional descriptive study. One hundred mothers were selected through convenient purposes sampling. Chi-square test applied for an association between mode of delivery and initiation of breastfeeding.
RESULTS: The result of the study showed variability in the time of breastfeeding by the mothers from one hour to 24 hours after delivery. Pre-lacteal was given to 59 mothers, while 41 were not given with any pre-lacteal. A significant association was found between mode of delivery and initiation of breastfeeding with a p-value less than 0.001
CONCLUSION: The result of the study showed that variability in the time of breastfeeding by the mothers from one hour to 24 hours after delivery provided a significant difference in the production of the neonate in the first 28 days.
Cimiracemate A confers protection on arthritic neonatal rats via regulation of iNOS/NF-κB/TLR-4 pathway
Authors: Zou Jun , Peng Kun , Xiong Tao , Xiong Zhi G. , Hu Niya 
Published: May 2021

Purpose: To investigate the protective effect of cimiracemate A on Freund’s adjuvant-induced rheumatoid arthritis (RA) in neonatal rats, and the underlying mechanism.
Methods: Rheumatoid arthritis was induced in rat pups using Complete Freund’s adjuvant (100 µg/100 µL/body weight) which was intra-dermally injected at the tail region. After 21 days of establishment of RA, the rats were randomly assigned to four groups of ten rats each: control group, RA group, 5 mg/kg cimiracemate A group, and 10 mg/kg cimiracemate A group. Cimiracemate A was orally administered for 45 days. The effect of cimiracemate A on oxidative stress biomarkers, superoxide dismutase (SOD), malondialdehyde (MDA) and reduced glutathione (GSH) were determined using standard methods. Plasma levels of the inflammatory cytokines interleukin 1β (IL-1β) and tumor necrosis factor-α (TNF-α), and prostaglandin E2 (PGE-2) and matrix metalloproteinase-3 (MMP-3) were determined using enzyme-linked immunosorbent assay (ELISA). Western blotting was used to determine the levels of protein expressions of iNOS, NF-κB and TLR-4.
Results: The level of MDA significantly increased and the level of GSH significantly decreased in RA group relative to control group (p < 0.05) following treatment with cimiracemate A. SOD activity was significantly reduced in RA group, when compared with control group (p < 0.05). However, treatment with cimiracemate A significantly and dose-dependently reversed the altered levels of MDA and GSH and SOD activity, when compared with RA group (p < 0.05). Plasma levels of IL-1β, TNF-α, PGE-2 and MMP-3 were significantly higher in RA group than in control group, but were significantly and dosedependently reduced after treatment with cimiracemate A (p < 0.05). There were significant increases in the levels of expression of iNOS, NF-κB and TLR-4 proteins in the chondrocytes of RA group, relative to control group (p < 0.05). However, treatment with cimiracemate A significantly and dose-dependently down-regulated the expressions of these proteins, when compared with RA group (p < 0.05).
Conclusion: The results of this study indicate that cimiracemate A confers some degree of protection on arthritic neonatal rats via a mechanism that involves regulation of iNOS/NF-κB/TLR-4 pathway.
RACIOCÍNIO PEDAGÓGICO DE PROFESSORES ACERCA DO ENSINO DO EMPREENDEDORISMO NA ENFERMAGEM
Authors: Mirela Oliveira Amaral Thayza , do Carmo Menegaz Jouhanna , Coelho Toscano Silveira Stelacelly , Campo Meschial William , Leonardo Figueireido Cunha Carlos , Geórgia Monteiro Dias e Silva Clarice 
Published: May 2021

Objetivo: analisar o raciocínio pedagógico de professores sobre o ensino do empreendedorismo na enfermagem. Método: Estudo quali-quantitativa, fundamentado no método e-Delphi. Os participantes foram professores de universidades públicas de cursos de graduação em Enfermagem. Para a seleção, utilizou-se a técnica de bola de neve (snow-ball). Para a análise dos dados qualitativos foi utilizada a análise de conteúdo de Bardin, e para a análise dos dados quantitativos das demais rodadas foi utilizada a estatística descritiva, com cálculo de frequência. Resultados: Identificou-se perspectivas a respeito do ensino do empreendedorismo na enfermagem e da prática docente neste processo. Conclusão: As escolas e professores são essenciais para fortificar o empreendedorismo na enfermagem, principalmente no cenário atual em que o mesmo ainda é incipiente. Realizar estudos como este possibilita que instituições de ensino superior acompanhem as mudanças que ocorrem no mundo, para formar profissionais capazes de atender as demandas do mercado de trabalho.
Descritores: Enfermagem; Ensino; Educação em Enfermagem; Mercado de Trabalho.
Assessing the Serviceability Status of Existing Transport Network by Using Geospatial Techniques in Metropolitan City Lahore
Authors: Fatima Syeda Jabeen , Javed Muhammad Asif , Ahmed Sajid Rashid 
Published: May 2021

Reliable and an efficient Public Transport plays key role in establishing sustainable Urban Transport system and healthy environment in any city. Public Transport equity in terms of easy access for the commuters is very crucial. With the drastic increase in population and cities extent in developing countries like Pakistan, the travel demand is recklessly increasing which urge to provide efficient public transit which may cater the ever increasing transport demand. Lahore being the provincial capital of Punjab and the second most densely populated city of Pakistan, has a remarkably large transportation network. The case study presented an advanced approach to determine the population with walking access to transit stop of Lahore Public Transport network, by using Geographical Information System (GIS). This approach is quite efficient, reliable and helpful to investigate the effectiveness of transit network, user's access to transit stops and spatial gaps in the transit facilities. GIS-based network service area analysis has been utilized to find the transit stop service area of the existing public transport network in metropolitan city Lahore. To find the transit stop service area, suitable walking time of 8 min or threshold distance of 624 m with walking speed of 78 m/min has been used as a standard. Transit stop service area has been used to find the population with walking access to a transit stop. The results reveal that only 40% of the total population was in suitable walking distance, which shows that less serviceability is due to the improper spatial distribution of existing transit stops across the transit route. The results also identify the population which is not in suitable walking distance to transit service. This study concludes that Geospatial Techniques are significant in assessment of the effectiveness and subsequently measuring the gaps in the existing transport network. Thus, on the basis of these results sustainable solution would be presented to enhance the efficacy of the integrated public transport.
L’impact de la dimension culturelle en évaluation et en intervention psychiatriques et légales
Authors: Dembri A. N. , Costi T. , Sanchez M.A. 
Published: May 2021

Le présent article situe les données du problème reliées au rôle de l’intervenant d’origine ethnique en psychiatrie légale. Il soulève les points saillants concernant l’évaluation clinique et le diagnostic de patients d’ethnies autres que Québécoise.
Un éclairage sur la problématique de l’émigré, sur les liens existant entre santé mentale et culture seront exposés. Un cas clinique étayera notre réflexion.
Nos conclusions réfutent la nécessité d’être d’une même origine ethnique pour prendre en charge ou traiter un patient. Mais lors d’évaluations ou d’expertises psychiatriques et légales, la présence de l’intervenant homoethnique qui crée un « pont inter culturel » entre le clinicien et le patient est importante. C’est ce rôle de coordination et de jonction entre deux cultures que devraient jouer les cliniques transculturelles.
Mango Peels and Kernels from Selected Varieties of Côte d’ivoire are Potential Sources of Antioxidative Bioactive Compounds
Authors: Koua Gisèle Y. , Zoue Lessoy T. , Akoa Edwige 
Published: May 2021

Aims: This study aimed to quantify the bioactive compounds and the antioxidant activity of mango peels and kernels from two main varieties (Kent, Keitt) cultivated in Côte d’Ivoire.
Study Design: Processing of mango varieties, determination of bioactive compounds content of mango peels and kernels, evaluation of antioxidant activity of mango peels and kernels.
Place and Duration of Study: Felix Houphouet-Boigny University, Biotechnology Laboratory (March to September 2019).
Methodology: Ripe mango (Mangifera indica L) fruits from Kent and Keitt varieties were processed to obtain peels and kernels powders. Methanolic extracts of peels and kernels were used to determine the content of phenolics, flavonoids and tanins while hexanic extracts were used to determine the content of carotenoids and phytosterols. DPPH scavenging and ferric reducing power tests were used to evaluate antioxidant activity of peels and kernels.
Results: Total phenolics content of kernels of Kent (4371.22 ± 24.98 mg/100g dw) and Keitt (4037.93 ± 20.43 mg/100g dw) were higher (P ˂ 0.05) than those of peels from the two varieties (2564.37 – 3082.07 mg/100g dw). The values for carotenoids content of peels varied from 37.53 to 57.74 μg/g dw while those of kernels varied from 1.48 to 3.46 μg/g dw. Based on DPPH test The IC50 values ranged from 0.2 to 0.7 mg/mL with the highest antioxidant activity reported for kernels from Kent variety. The absorbance at 700 nm was found to be 0.4 for kernel of Keitt variety and 0.3 for ascorbic acid at a dose level of 0.03 mg/mL.
Conclusion: Peels and kernels from Kent and Keitt varieties are potential sources of bioactive compounds especially phenolics, tanins, carotenoids and phytosterols. These valuable bioactive compounds in mango by-products may have greater application in the food, cosmetic and pharmaceutical industries.
Copper‐Catalyzed Selective N‐Arylation of Oxadiazolones by Diaryliodonium Salts
Authors: Soldatova Natalia S. , Semenov Artem V. , Geyl Kirill K. , Baykov Sergey V. , Shetnev Anton A. , Konstantinova Anna S. , Korsakov Mikhail M. , Yusubov Mekhman S. , Postnikov Pavel S. 
Published: May 2021

AbstractHere, we report the method for copper‐catalyzed N‐arylation of diverse oxadiazolones by diaryliodonium salts under mild conditions in high yields (up to 92%) using available CuI as a catalyst. The developed method allows utilizing both symmetric and unsymmetric diaryliodonium salts bearing auxiliary groups such as 2,4,6‐trimethoxyphenyl (TMP). We found that the steric effects in aryl moieties determined the chemoselectivity of N‐ and O‐arylation of the 1,2,4‐oxadiazol‐5(4H)‐ones. Mesityl‐substituted diaryliodonium salts demonstrated the high potential as a selective arylation reagent. The structural study suggests that steric accessibility of N‐atom in 1,2,4‐oxadiazol‐5(4H)‐ones impact to arylation with sterically hindered diaryliodonium salts. The synthetic application of proposed method was also demonstrated on selective arylation of 1,3,4‐oxadiazol‐2(3H)‐ones and 1,2,4‐oxadiazole‐5‐thiol.magnified image
Plant Natural Flavonoids Against Multidrug Resistant Pathogens
Authors: Song Meirong , Liu Ying , Li Tingting , Liu Xiaojia , Hao Zhihui , Ding Shuangyang , Panichayupakaranant Pharkphoom , Zhu Kui , Shen Jianzhong 
Published: May 2021

AbstractThe increasing emergence and dissemination of multidrug resistant (MDR) bacterial pathogens accelerate the desires for new antibiotics. Natural products dominate the preferred chemical scaffolds for the discovery of antibacterial agents. Here, the potential of natural flavonoids from plants against MDR bacteria, is demonstrated. Structure–activity relationship analysis shows the prenylation modulates the activity of flavonoids and obtains two compounds, α‐mangostin (AMG) and isobavachalcone (IBC). AMG and IBC not only display rapid bactericidal activity against Gram‐positive bacteria, but also restore the susceptibility of colistin against Gram‐negative pathogens. Mechanistic studies generally show such compounds bind to the phospholipids of bacterial membrane, and result in the dissipation of proton motive force and metabolic perturbations, through distinctive modes of action. The efficacy of AMG and IBC in four models associated with infection or contamination, is demonstrated. These results suggest that natural products of plants may be a promising and underappreciated reservoir to circumvent the existing antibiotic resistance.
Multistage distributionally robust optimization for integrated production and maintenance scheduling
Authors: Feng Wei , Feng Yiping , Zhang Qi 
Published: May 2021

AbstractIn chemical manufacturing processes, equipment degradation can have a significant impact on process performance or cause unit failures that result in considerable downtime. Hence, maintenance planning is an important consideration, and there have been increased efforts in scheduling production and maintenance operations jointly. In this context, one major challenge is the inherent uncertainty in predictive equipment health models. In particular, the probability distribution associated with the stochasticity in such models is often difficult to estimate and hence not known exactly. In this work, we apply a distributionally robust optimization (DRO) approach to address this problem. Specifically, the proposed formulation optimizes the worst‐case expected outcome with respect to a Wasserstein ambiguity set, and we apply a decision rule approach that allows multistage mixed‐integer recourse. Computational experiments, including a real‐world industrial case study, are conducted, where the results demonstrate the significant benefits from binary recourse and DRO in terms of solution quality.
Population estimate of people with clinical Alzheimer's disease and mild cognitive impairment in the United States (2020–2060)
Authors: Rajan Kumar B. , Weuve Jennifer , Barnes Lisa L. , McAninch Elizabeth A. , Wilson Robert S. , Evans Denis A. 
Published: May 2021

AbstractIntroductionThe estimate of people with clinical Alzheimer's disease (AD) and mild cognitive impairment provides an understanding of the disease burden.MethodsWe estimated people with cognitive impairment using a quasibinomial regression model in 10,342 participants with cognitive test scores.ResultsThe 2020 US Census–adjusted prevalence of clinical AD was 11.3% (95% confidence interval [CI] = 10.7–11.9): 10.0% among non‐Hispanic Whites, 14.0% among Hispanics, and 18.6% among non‐Hispanic Blacks. We estimate that in 2020, 6.07 (95% CI = 5.75–6.38) million people were living with clinical AD, which increases to 13.85 (95% CI = 12.98–14.74) million in 2060, 423% higher among Hispanics, 192% higher among Blacks, and 63% higher among Whites. However, there are predicted to be more significant increases in later years among those over 85 and women compared to men.DiscussionThe number of people with clinical AD will increase as the “baby boom” generation reaches older ages, exerting a strong upward influence on disease burden.