bluuebunny/crossref_metadata_2025_split huggingface dataset:
Smart and Agile Turnaround Management
Authors: Audrain Philippe 
Published: December 2021

Abstract
Oil&Gas facilities operators are looking for safe and efficient Turnaround cycles with minimum downtime. However planning such project, ensuring availability of materials, of equipment and of skilled personnel, as well as orchestrating the hundreds of processes and stakeholders involved in the execution to keep it on schedule and on budget is a huge and complex challenge. How to handle and take into account what is planned and what is unplanned?
A Turnaround project can be managed with similar approach than an EPC (Engineering Procurement Construction) project. It should leverage collaborative best practices developed to handle capital projects. Those practices allow to plan more productively, to execute with agility while taking into account unplanned changes "on the fly" without affecting on-going activities. A digital collaborative platform enables integrated knowledge as well as real-time visibility into every aspect of the Turnaround. It provides seamless collaboration for productive planning and intelligent execution. This is a strategy, which eliminates unproductive tasks and brings stakeholders together in a dynamic, collaborative management system.
With better orchestration, plant owners and operators can reduce their planning and preparation workload by around 30% with also positive impact on all subcontractors. With a better seamless execution, plant owners and operators can get things done right the first time and recover to unplanned events. They can reduce the risk to be out of schedule and keep on track with more margin. They can even reduce the execution time by up to 5% in some situation. Finally, it enforces the reuse of insights that are gathered along Turnarounds to improve safety and extend by 20% the cycle in future Turnaround.
A 3D collaborative platform provides an easy to use single source of truth to manage and monitor a Turnaround. Using such 3D environment, one can quickly identify the location of an issue where potential bottlenecks occur, and get access to any relevant vendor's specification, inspection or maintenance history report. Such 3D platform can also help to easily track with color-coding the leak test results of the many joints and their potential disturbances after Turnaround inspection.
Procedural Automation of Ethane Recovery to Rejection in NGL Trains
Authors: Sengupta Subhendu , Goveas Vincent 
Published: December 2021

Abstract
This paper is based on successful implementation of procedural automation of Ethane (C2) recovery - rejection mode change using Yokogawa's Exapilot software, wherein ADNONC Gas Processing Habshan 5 & Sulphur management approved the implementation based on similar success of the Sulphur Recover Unit start-up/shutdown procedural automation & company's drive for digitalisation.
Scope was to develop modules for automating C2 Recovery /Rejection change over procedure in NGL unit using M/s Yokogawa Exapilot software.
These automated procedures aimed to standardize said mode change over operations by incorporating the operating know how and the expertise of skilled-experienced operators into the Exapilot system as a set of Standard Operating Procedures (SOPs) that are executed in right operating sequence for enhanced operating efficiency.
Two main procedures & associated modules were designed, engineered and built using Exapilot to enable single-click change over automation for NGL units. Those were validated with operation and deployed in the Exapilot Server and were integrated with the Operator Consoles (HIS) for access, and was supplemented with operator training.
Ethane Recovery to Rejection Mode Change Ethane Rejection to Recovery Mode Change
Besides standardization and reduced change over time, this improved the critical asset integrity and lifespan of NGL section equipment by advocating systematic operations.
Following benefits including major take away from this project:
➢ Standardized the mode change-over procedures & minimized human error by the digitalization of paper documentation procedures into electronic workflow process. Procedural Automation like Exapilot is powerful tool for digital transformation of batch/discrete operation like unit/equipment start-up/shutdown or grade/mode change over. ➢ Reduced inherent delay due to manual change over. Hence, minimizing the loss-opportunities & operating cost. Besides this tool can be used as training tool (when used in offline mode) which help operator succession plan & effective knowledge transfer ➢ Automated critical operation such as temperature/flow ramping, improved equipment integrity and prolonged equipment life. Procedural Automation using Exapilot thus can improve operation efficiency, asset integrity, equipment or material life span
This paper presents a success story of procedural automation of batch operation in continuation of similar success in SRU start-up & shutdown automation. This tool along with proper integration work with DCS, has opened door for automation/digitalization in batch operation in continuous process not only in other sites of ADNOC Gas Processing and other ADNOC Group Companies but also in other industries that helps companies to enhance efficiency and fulfil their digitalization journey. Though Exapilot software belongs to M/s Yokogawa, however other DCS systems have similar software such as Honeywell DCS EPKS has E-procedure for procedural automation.
Effects of Baduanjin Exercise on Cognitive Function and Cancer-related Symptoms in Women With Breast Cancer Receiving Chemotherapy: a Randomized Controlled Trial
Authors: Wei Xiaolin , Yuan Ruzhen , Yang Juan , Zheng Wei , Jin Yongmei , Wang Mingyue , Jiang Jieting , Wu Caiqin , Li Kunpeng 
Published: December 2021

Abstract
Purpose Cognitive decline is one of the main side effects of breast cancer patients after relevant treatment, but there is a lack of clear measures for prevention and management without definite mechanism. Moreover, postoperative patients also have a need for limb rehabilitation. Whether the cognitive benefits of Baduanjin exercise can improve the overall well-being of this breast cancer patients remains unknown. This study aims to figure out these problems in the under-researched Chinese population.Methods This randomized controlled trial was conducted on 70 patients with breast cancer undergoing chemotherapy who were randomly assigned and allocated to (1:1) the supervised Baduanjin group (5 times/week, 30 min each time) or the control group for three months. The effects of Baduanjin exercise intervention were evaluated by outcome measures including subjective cognitive function, symptoms (fatigue, depression and anxiety) and health-related quality of life at pre-intervention (T0), 4 weeks (T1), 8 weeks (T2) and 12 weeks (T3). The collected data were analyzed by using an intention-to-treat principle and linear mixed-effects modeling.Results Participants in the Baduanjin group had a significantly greater improvement in terms of FACT-cog (F=14.511; P < 0.001), PCI (F=15.915; P < 0.001), PCA (F=2.767; P= 0.047), and health-related quality of life (F=8.900; p = 0.004) compared with the control group over the time. The exercise-cognition relationship was significantly mediated by reduced fatigue (indirect effect: β= 0.132; 95% CI: 0.046, 0.237) and improved anxiety (indirect effect: β=-0.075; 95% CI: -0.165, -0.004).Conclusions This pilot study revealed the benefits and outlined the underlying mediating mechanism of Baduanjin exercise to the subjective cognition and health-related quality of life of Chinese breast cancer patients receiving chemotherapy. The findings provided insights into the development of public health initiatives to promote brain health and improve quality of life among breast cancer patients.Trial registration number ChiCTR 2000033152
Maternity Care Services Utilization and Factors Associated with Institutional Delivery Among Postpartum Women in Dabat Demographic and Health Survey Site, Northwest Ethiopia: A Community Based Baseline Survey for MNCH Surveillance
Authors: Gelagay Abebaw Addis , Worku Abebaw Gebeyehu , Bashah Debrework Tesgera , Tebeje Nigusie Birhan , Gebrie Mignote Hailu , Yeshita Hedija Yenus , Cherkose Endeshaw Adimasu , Lakew Ayenew Molla , Dachew Berihun Assefa , Tariku Amare , Belew Aysheshim Kassahun , Ayana Birhanu Abera , Bikes Gashaw Andargie 
Published: December 2021

Abstract
Background
Maternal continuum of care is identified to have a greatest impact on maternal and child survival. However, there is a wide variation in maternal health services utilization from place to place in Ethiopia. Therefore, knowing antenatal care, labor and delivery, and postnatal care uptake has paramount importance to take interventions.
Methods
A community-based cross-sectional survey was conducted among 1626 postpartum women. Descriptive statistics were done to characterize the study population and utilization of antenatal care, institutional delivery, and postnatal care services. Logistic regression analysis was employed to identify factors associated with institutional delivery.
Results
Nearly eighty percent, (79.7%, 95% CI: 77.7, 81.6), of women attended at least one antenatal care visit at any health facility. However, only less than one third (31.4%) used all the recommended antenatal care (ANC). About half, 820 (49.2%: 95% CI: 46.7, 51.8) women delivered their child in health institution. About half, 822 (50.6%, 95% CI: 48.2, 52.9) of postpartum women who participated in this study had at least one postnatal care (PNC) visit at health facilities. Being urban resident (AOR=8.18, 95%CI: 4.69, 14.26)), respondents of higher educational status (AOR= 4.99, 95%CI: 2.51, 9.90), being Orthodox Christian (AOR= 2.35, 95%CI: 1.15, 4.79), getting TT vaccination during pregnancy (AOR=1.54, 95%CI: 1.06, 2.23), and antenatal care utilization (AOR=2.97, 95%CI: 2.06, 4.27) were predictors for health facility/institutional delivery.
Conclusions
Though a significant proportion of the study participants initiated antenatal care, utilization of all the recommended antenatal care visits, facility delivery, and postnatal care services were low. Health professionals need to use the first antenatal care visit as a golden opportunity to attract and maintain pregnant women for the subsequent maternal health care services.
Drought-induced Forest Dieback Increases Taxonomic and Functional Diversity But Not Phylogenetic Diversity of Saproxylic Beetles at Both Local and Landscape Scales
Authors: Cours Jérémy , Sire Lucas , Ladet Sylvie , Martin Hilaire , Parmain Guillem , Larrieu Laurent , Moliard Carl , Lopez-Vaamonde Carlos , Bouget Christophe 
Published: December 2021

Abstract
Context: Forest ecosystems worldwide are facing increasing drought-induced dieback, causing mortality patches across the landscape at multiple scales. This increases the supply of biological legacies and differentially affects forest insect communities.Objectives: We analysed the relative effects of local- and landscape-level dieback on local saproxylic beetle assemblages. We assessed how classic concepts in spatial ecology (e.g. habitat-amount and habitat-patch hypotheses) are involved in relationships between multi-scale spatial patterns of available resources and local communities.Methods: We sampled saproxylic beetle assemblages in commercial fir forests in the French highlands. Through automatic aerial mapping, we used dead tree crowns to assess dieback levels at several nested spatial scales. We analysed beetle taxonomic, phylogenetic and functional diversity related to differing levels of multi-scale dieback.Results: In line with the habitat-amount hypothesis, taxonomic and functional diversity, but not phylogenetic diversity, of beetle assemblages significantly benefitted from forest dieback, at both local and landscape scales. Very few single or interaction effects were detected in the multiplicative models combining local and landscape variables, though a significant positive effect of landscape-scale dieback on the abundance of cavity- and fungus-dwelling species was consistent with a spill-over effect. Increased landscape-scale dieback also caused a functional specialisation of beetle assemblages, favouring those related to large-diameter, well-decayed deadwood.Conclusions: Increasing tree mortality under benign neglect provides conservation benefits by heterogenising the forest landscape and enhancing deadwood habitats. Legacy retention practices could take advantage of unharvested, declining forest stands to promote species richness and functional diversity within conventionally managed forest landscapes.
Bibliometric study of the combustion of cane cutting waste (RAC) in the capture of Carbon Dioxide.
Authors: PEÑA SANDRA EMPERATRIZ , FORERO CARMEN , VELASCO FRANCISCO 
Published: December 2021

Abstract
Objective: To describe the combustion process of sugarcane RAC with CO2 capture by manganese-based oxygen transporters during the period from 2015 to 2021. Design: Bibliometric observational study. Location: Combustion of cutting waste with CO2 capture by manganese-based oxygen conveyors.Main measures: Magazine, year of publication, first/last author, workplace and autonomous community were obtained in each register. Subsequently, the articles were classified according to their content or research area. The impact factor was obtained from the bibliometric analysis base of Scopus and Vos viewer.Results: Using the search criteria, 475 documents were recovered in the 2015-2021 period, excluding 2637 because they did not correspond to affiliation with centers or institutions directly related to documents related to chemical combustion and CO2 capture. In total, 73 documents were selected, in which an increase and interest in the study of these processes was verified both in the research areas and in the journals in which they are published. Most of the studies have been published in universities or research centers, and differences were observed in terms of the volume of international and national scientific production, so it is necessary to increase these investigations in Colombia.
Cold Shock Induced Oxidative Stress, Apoptosis and Genome-wide Gene Expression Perturbation in the Eyes of Zebrafish and the Mitigation of Blue Wavelength Light
Authors: Peng Li-Bin , Han Tao , Wen Zhengshun , Cheng Xiao , Wang Dan , Zhu Qing-Ling , Wang Ping , Zheng Jia-Lang 
Published: December 2021

Abstract
As global climate changes, severely temperature variations have significant impacts on survival and development of fish. While the potential effects of light wavelength on cold shock and associated mechanisms remain largely unknown in fish. Here, zebrafish were pre-exposed to white LEDs (an irradiance of 0.9 W/m2) and blue LEDs (LDB, peak at 450 nm, 0.9 W/m2) for 2 weeks, and then exposed to 26℃ or 11℃ for 48 hours, respectively. Cold shock led to low survival rate. Cold shock altered retinal structure, increased the number of apoptotic cells and Caspase-3 activity, inhibited superoxide dismutase (SOD) and catalase (CAT) activities, up-regulated mRNA expression of (NF-E2-related factor 2) nrf2, p53, casp3 and casp9, and down-regulated cat expression in fish eyes. These results demonstrated that acute cold exposure induced oxidative stress and apoptosis in zebrafish eyes, which may lead to mortality. However, cold shock in combination with LDB apparently mitigated these negative effects, which might be involved in the up-regulation of antioxidant response and down-regulation of apoptotic responses at transcriptional and translational levels. Furthermore, cold shock also caused dysregulation of genome-wide gene expression involved in circadian rhythm, phototransduction and il-17 signaling pathway, indicating that cold shock disturbed phototransduction cascade and circadian rhythm signals and caused inflammatory responses. Ten key genes involved in circadian rhythm, phototransduction, cell cycle arrest, RNA processing or inflammatory responses were identified, including muc5d, rnps1, si:dkey-243i1.1, opn1mw1, gadd45ba, cebpd, btg2, si:dkey-242g16.2, nr1d1 and zgc:122979, which may play an important role in the protection of LDB against cold shock. Finally, our study suggested the relationship between spectrum and cold stress and demonstrated LDB could protect fish against the negative effect of cold stress in the eyes.
A Generative Adversarial Inpainting Network to Enhance Prediction of Periodontal Clinical Attachment Level
Authors: Kearney Vasant , Yansane Alfa-Ibrahim M. , Brandon Ryan G. , Vaderhobli Ram , Lin Guo-Hao , Hekmatian Hamid , Deng Wenxiang , Joshi Neha , Bhandari Harsh , Sadat Ali S. , White Joel M. 
Published: December 2021

Abstract
Deep learning algorithms has recently been used to determine clinical attachment levels (CAL) which aid in the diagnosis of periodontal disease. However, the limited field-of-view of dental bitewing x-rays poses a challenge for convolutional neural networks (CNN) because out-of-view anatomy cannot be directly considered. This study presents an inpainting algorithm using generative adversarial networks (GANs) coupled with partial convolutions to predict out-of-view anatomy to enhance CAL prediction accuracy. 80,326 images were used for training, 12,901 images were used for validation and 10,687 images were used to compare non-inpainted methods to inpainted methods for CAL predictions. Statistical analyses were conducted using mean bias error (MBE), mean absolute error (MAE) and Dunn’s pairwise test comparing CAL at p=0.05. Comparator p-values demonstrated statistically significant improvement in CAL prediction accuracy between corresponding inpainted and non-inpainted methods with a MAE of 1.04mm and 1.50mm respectively. The Dunn’s pairwise test indicated a statistically significant improvement in CAL prediction accuracy between both inpainted methods compared to their non-inpainted counterparts, with the best performing methods achieving a Dunn’s pairwise value of -63.89. This study demonstrates the superiority of using a generative adversarial inpainting network with partial convolutions to predict CAL from bitewing images.
Incidence of Hypoglycemia and Hospitalization Related to Chronic Diabetes Complications and Its Effect on Quality of Life Among Patients Initiating Second Line Therapy: DISCOVER Study
Authors: Al-Rubeaan Khalid , Banah Faisal , Alruwaily Fayez , Sheshah Eman , Alnaqeb Dhekra , AlQahtani Awad , Ewais Diaa , Juhani Nassr Al , Hassan Abdul-hameed , Youssef Amira 
Published: December 2021

Abstract
The management of patients with type 2 diabetes is a complex process that must be individualized and be patient centered. The aim of this study was to assess the metabolic control, the annual incidence and crude prevalence of hypoglycemia, hospitalization, and complications among patients with type 2 diabetes initiating second-line therapy. This study is an observational, longitudinal, prospective study as a part of the multinational DISCOVERing Treatment Reality of Type 2 Diabetes in Real World Settings (DISCOVER) study, that recruited 519 patients with type 2 diabetes who were non-insulin users, aged ≥18 years, and switching to second-line therapy. The cohort was clinically evaluated over three years of follow up. Fear of hypoglycemia was assessed using the Hypoglycemia Fear Survey (HFS II), while the quality of life was assessed using SF36v2 questionnaire. Using second-line therapy improved metabolic control but the annual incidence of microangiopathies were at 61/1000 patient-years, 47/1000 patient-years, and 4/1000 patient-years for neuropathy, retinopathy, and nephropathy, respectively. The incidence of hypoglycemia was 57/1000 patient-years, where 50% were recurrent during the three-years period. The HFS II showed a significant increase in patients’ worries related to hypoglycemia. The incidence of hospitalization was 31/1000 patient-years, out of which 8/1000 patient-years were related to cardiovascular events, mainly myocardial infarction. Moderate metabolic control was associated with lower incidence of macro angiopathy and an increased incidence and fear of hypoglycemia, while it was associated with improved mental component score when assessing the patients’ quality of life. The treating physician’s decision of treatment intensification should be individualized with consideration of befits of good glycemic control versus the risk of hypoglycemia, especially in elderly patients.
A 5-km-thick reservoir with &gt;380,000 km3 of magma within the ancient Earth's crust
Authors: Latypov Rais , Chistyakova Sofya , Hornsey Richard , Costin Gelu , Merwe Mauritz van der 
Published: December 2021

Abstract
Several recent studies have argued that large, long-lived and molten magma chambers1–10 may not occur in the shallow Earth’s crust11–23. Here we present, however, field-based observations from the Bushveld Complex24 that provide evidence to the contrary. In the eastern part of the complex, the magmatic layering was found to continuously drape across a ~4-km-high sloping step in the chamber floor. Such deposition of magmatic layering implies that the resident melt column was thicker than the stepped relief of the chamber floor. Prolonged internal differentiation within such a thick magma column is further supported by evolutionary trends in crystallization sequence and mineral compositions through the sequence. The resident melt column in the Bushveld chamber during this period is estimated to be >5-km-high in thickness and >380,000 km3 in volume. This amount of magma is three orders of magnitude larger than any known super-eruptions in the Earth’s history25 and is only comparable to the extrusive volumes of some of Earth’s large igneous provinces26. This suggests that super-large, entirely molten and long-lived magma chambers, at least occasionally, occur in the geological history of our planet. Therefore, the classical view of magma chambers as ‘big magma tanks’1–10 remains a viable research concept for some of Earth’s magmatic provinces.
Tight association of autophagy and cell cycle in leukemia cells
Authors: Gschwind Alena , Marx Christian , Just Marie D. , Severin Paula , Behring Hannah , Marx-Blümel Lisa , Becker Sabine , Rothenburger Linda , Förster Martin , Beck James F. , Sonnemann Jürgen 
Published: December 2021

Abstract
BackgroundAutophagy plays an essential role in maintaining cellular homeostasis and in the response to cellular stress. Autophagy is also involved in cell cycle progression, yet the relationship between these processes is not clearly defined.ResultsIn exploring this relationship, we observed that the inhibition of autophagy impaired the G2/M phase-arresting activity of etoposide but enhanced the G1 phase-arresting activity of palbociclib. We further investigated the connection of basal autophagy and cell cycle by utilizing the autophagosome tracer dye Cyto-ID in two ways. First, we established a double-labeling flow-cytometric procedure with Cyto-ID and the DNA probe DRAQ5, permitting the cell cycle phase-specific determination of autophagy in live cells. This approach demonstrated that different cell cycle phases were associated with different autophagy levels: G1 phase cells had the lowest one and G2/M phase cells had the highest one. Second, we developed a flow-cytometric cell sorting procedure based on Cyto-ID that separates cell populations into fractions with low, medium and high autophagy. Cell cycle analysis of Cyto-ID-sorted cells confirmed that the high autophagy fraction contained a much higher percentage of G2/M phase cells than the low autophagy fraction. Beyond that, Cyto-ID-based cell sorting proved also to be useful for assessing other autophagy-related processes: extracellular flux analysis revealed metabolic differences between the cell populations, with higher autophagy being associated with higher respiration, higher mitochondrial ATP production and higher glycolysis.ConclusionThis work sheds new light on the interrelation of autophagy and cell cycle by establishing a novel cell sorting technique based on Cyto-ID.