bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association Between Morning Surge in Systolic Blood Pressure and SYNTAX Score I in Patients With Stable Coronary Artery Disease
Authors: Quisi Alaa , Alici Gokhan , Harbalioglu Hazar , Genc Omer , Kurt Ibrahim Halil , Cayli Murat 
Published: June 2021

A high morning surge in systolic blood pressure poses a risk in people who have cardiovascular disease. We investigated the relationship between this phenomenon and the SYNTAX score I in patients who had stable coronary artery disease.
Our single-center study included 125 consecutive patients (109 men and 16 women; mean age, 54.3 ± 9 yr) in whom coronary angiography revealed stable coronary artery disease. We calculated each patient's sleep-trough morning surge in systolic blood pressure, then calculated the SYNTAX score I.
The morning surge was significantly higher in patients whose score was >22 (mean, 22.7 ± 13.2) than in those whose score was ≤22 (mean, 12.4 ± 7.5) (P <0.001). Forward stepwise logistic regression analysis revealed that morning surge in systolic blood pressure was the only independent predictor of an intermediate-to-high score (odds ratio=1.183; 95% CI, 1.025–1.364; P=0.021).
To our knowledge, this is the first study to show an association between morning surge in systolic blood pressure and the SYNTAX score I in patients who have stable coronary artery disease.
Ethics as Medicine: Moral Therapy, Expertise, and Practical Reasoning in al-Ghazālī’s Ethics
Authors: Vasalou Sophia 
Published: June 2021

Abstract
The idea that ethics might be fruitfully understood in analogy with, or indeed as a form of, medicine has enjoyed a long and distinguished history. A staple of ancient philosophical thinking, it also achieved wide expression in the Islamic world. This essay explores the role of the medical analogy in the work of the eleventh-century Muslim intellectual Abū Ḥāmid al-Ghazālī. Al-Ghazālī’s use of this analogy offers a unique vantage point for approaching several key features of his ethics of virtue, as notably expressed in the Revival of the Religious Sciences. These include his understanding of the nature of virtue and moral education; the fundamental structure of value; and most importantly, the place of human reasoning in the ethical life. This analogy also illuminates the rhetorical context of the Revival, taken as a book that aims to foster skills of practical reasoning and train its readers to become their own physicians.
Comparison of the analytical performance of the PATHFAST high sensitivity cardiac troponin I using fresh whole blood vs. fresh plasma samples
Authors: Gopi Vinajak , Milles Barbara , Spanuth Eberhard , Müller-Hennessen Matthias , Biener Moritz , Stoyanov Kiril , Frey Norbert , Giannitsis Evangelos 
Published: June 2021

Abstract

Objectives
The PATHFAST hs-cTnI (high-sensitivity cardiac troponin) assay is the first point-of-care assay with a high-sensitivity designation that received FDA approval for diagnosis of myocardial infarction (MI). Testing from whole blood does not need centrifugation and therefore is faster and more convenient in the emergency room instead of plasma. However, there is sparse evidence whether point-of-care testing of Tn from whole blood is as reliable as from plasma samples.

Methods
We investigated the agreement between plasma and whole blood hs-cTnI by using the PATHFAST hs-cTnI assay. Hs-cTnT measured on Cobas 602 in the central laboratory and compared to a final diagnosis of NSTEMI using serial hs-cTnT served as reference. We assessed biases, limits of agreement (±1.96 SD) and coefficients of correlation, and tested the discriminatory ability of the baseline sample of plasma and whole blood hs-cTnI and plasma hs-cTnT to discriminate non-ST-segment elevation myocardial infarction (NSTEMI).

Results
A total of 224 paired fresh samples were collected simultaneously from 191 patients presenting with suspected acute coronary syndrome. There was an excellent correlation between plasma and whole blood hs-cTnI (r=0.99), and a very good inter-rater agreement (k=0.93) between elevated and normal plasma and whole blood results. Precision evaluation according to CLSI ep 15 revealed comparable coefficients of variation (CV) in whole blood and plasma. The discriminatory ability of baseline hs-cTnT, plasma and whole blood hs-cTnI was excellent (AUC 0.967, AUC 0.954 and AUC 0.953) without significant difference.

Conclusions
Whole blood can be used interchangeably with plasma for more convenient and less time and labor-consuming testing of hs-cTnI on the PATHFAST instrument.
Banhatti, revan and hyper-indices of silicon carbide Si2C3-III[n,m]
Authors: Zhao Dongming , Zahid Manzoor Ahmad , Irfan Rida , Arshad Misbah , Fahad Asfand , Ahmad Zahid , Li Li 
Published: June 2021

AbstractIn recent years, several structure-based properties of the molecular graphs are understood through the chemical graph theory. The molecular graphGGof a molecule consists of vertices and edges, where vertices represent the atoms in a molecule and edges represent the chemical bonds between these atoms. A numerical quantity that gives information related to the topology of the molecular graphs is called a topological index. Several topological indices, contributing to chemical graph theory, have been defined and vastly studied. Recent inclusions in the class of the topological indices are the K-Banhatti indices. In this paper, we established the precise formulas for the first and second K-Banhatti, modified K-Banhatti, K-hyper Banhatti, and hyper Revan indices of silicon carbideSi2C3{{\rm{Si}}}_{2}{{\rm{C}}}_{3}-III[n,m]{\rm{III}}\left[n,m]. In addition, we present the graphical analysis along with the comparison of these indices forSi2C3{{\rm{Si}}}_{2}{{\rm{C}}}_{3}-III[n,m]{\rm{III}}\left[n,m].
Impact of binding mode of low-sulfated hyaluronan to 3D collagen matrices on its osteoinductive effect for human bone marrow stromal cells
Authors: Vogel Sarah , Ullm Franziska , Müller Claudia Damaris , Pompe Tilo , Hempel Ute 
Published: June 2021

Abstract
Synthetically sulfated hyaluronan derivatives were shown to facilitate osteogenic differentiation of human bone marrow stromal cells (hBMSC) by application in solution or incorporated in thin collagen-based coatings. In the presented study, using a biomimetic three-dimensional (3D) cell culture model based on fibrillary collagen I (3D Col matrix), we asked on the impact of binding mode of low sulfated hyaluronan (sHA) in terms of adsorptive and covalent binding on osteogenic differentiation of hBMSC. Both binding modes of sHA induced osteogenic differentiation. Although for adsorptive binding of sHA a strong intracellular uptake of sHA was observed, implicating an intracellular mode of action, covalent binding of sHA to the 3D matrix induced also intense osteoinductive effects pointing towards an extracellular mode of action of sHA in osteogenic differentiation. In summary, the results emphasize the relevance of fibrillary 3D Col matrices as a model to study hBMSC differentiation in vitro in a physiological-like environment and that sHA can display dose-dependent osteoinductive effects in dependence on presentation mode in cell culture scaffolds.
Switched capacitor based single DC source boost multilevel inverter (S2-MLI) featuring isolation based soft charging with minimum device count
Authors: Debela Tamiru , Singh Jiwanjot 
Published: June 2021

Abstract
Multilevel inverters (MLIs) have formed a new wave of interest in research and industry. Switched capacitor-based multilevel inverters are used to avoid the need for multiple separated DC sources compared to cascaded MLIs. However, the inclusion of several capacitors creates problems such as high inrush current, voltage imbalance. To avoid these drawbacks, this paper proposes an isolation-based scheme by using a flyback converter in the switched capacitor multilevel inverter. Further, the overall topology provides step-up AC voltage across the load from a single DC source with fewer power switches. To generate a step-up five-level voltage across the load, switched capacitor-based multilevel inverter needs six power switches and only one capacitor. To get the appropriate switching operation to generate the NL-levels, phase disposition pulse width modulation (PD-PWM) has been developed. The extended nine-level S

2

-MLI is also discussed in this paper under different conditions as change in input source voltage and dynamic load change. Moreover, to prove the superior performance of switched-capacitor single DC source multilevel inverter (S2-MLI), comparative analysis with existing single DC source MLI has been performed. The effectiveness and feasibility of the proposed topology are tested with varieties of loads by simulation using Matlab/Simulink. To validate the simulation results, hardware implementation has been done of five-level S2-MLI considering resistive and motor load by using DSpace 1103 controller.
Shifted Legendre spectral collocation technique for solving stochastic Volterra–Fredholm integral equations
Authors: Abdelkawy Mohamed A. 
Published: June 2021

Abstract
This paper addresses a spectral collocation technique to treat the stochastic Volterra–Fredholm integral equations (SVF-IEs). The shifted Legendre–Gauss–Radau collocation (SL-GR-C) method is developed for approximating the FSV-IDEs. The principal target in our technique is to transform the SVF-IEs to a system of algebraic equations. For computational purposes, the Brownian motion W(x) is discretized by Lagrange interpolation. While the integral terms are interpolated by Legendre–Gauss–Lobatto quadrature. Some numerical examples are given to test the accuracy and applicability of our technique. Also, an error analysis is introduced for the proposed method.
Infinite line of equilibriums in a novel fractional map with coexisting infinitely many attractors and initial offset boosting
Authors: Almatroud A. Othman , Khennaoui Amina-Aicha , Ouannas Adel , Pham Viet-Thanh 
Published: June 2021

Abstract
The study of the chaotic dynamics in fractional-order discrete-time systems has received great attention in the past years. In this paper, we propose a new 2D fractional map with the simplest algebraic structure reported to date and with an infinite line of equilibrium. The conceived map possesses an interesting property not explored in literature so far, i.e., it is characterized, for various fractional-order values, by the coexistence of various kinds of periodic, chaotic and hyper-chaotic attractors. Bifurcation diagrams, computation of the maximum Lyapunov exponents, phase plots and 0–1 test are reported, with the aim to analyse the dynamics of the 2D fractional map as well as to highlight the coexistence of initial-boosting chaotic and hyperchaotic attractors in commensurate and incommensurate order. Results show that the 2D fractional map has an infinite number of coexistence symmetrical chaotic and hyper-chaotic attractors. Finally, the complexity of the fractional-order map is investigated in detail via approximate entropy.
Schelling’s Narrative Philosophy and Ankersmit’s Narrative Logic – Is There Any Philosophy to Narrative?
Authors: Filutowska Katarzyna 
Published: June 2021

AbstractThis paper considers the problem of a narrative philosophy according to F. W. J. Schelling and narrative logic according to Franklin Ankersmit. Referring to these examples, I ask whether there is any philosophy to narrative at all. First, I discuss Schelling’s views from his unfinished work “The Ages of the World,” as well as his later dialectics of mythology of revelation from the system of the ages of the world. I focus on a dialectics of figurative and speculative order, which is at the core of Schelling’s project to tell philosophy in the form of poetry and demonstrate the origins of Schelling’s narrative philosophy in his early, transcendental thought. Next, I juxtapose my findings with Ankersmit’s analysis of historians’ language. I also consider whether, and how, some of these ideas can be applied in contemporary narrative research.
First North African record of a melanistic common genet (Genetta genetta Linnaeus, 1758)
Authors: Ahmim Mourad , Aroudj Hafid , Aroudj Farouk , Saidi Saaid , Aroudj Samir 
Published: June 2021

Abstract
The common genet (Genetta genetta Linnaeus, 1758) is a rare and protected mammal species in Algeria. We report the first melanistic individual of this species ever recorded in North Africa. Such animals have only been recorded in Spain and Portugal so far. It is unclear why melanistic common genets seem to be so rare in its African range. More research is needed to determine the true occurrence of melanistic individuals, and what the evolutionary history of melanism is in common genets.
An apercu of the current status of women in ocean science
Authors: Brooks L. Anthea , Déniz-González Itahisa 
Published: June 2021

Abstract
This article complements the coverage of the status of women in ocean science as contained in the recently published Global Ocean Science Report 2020 – Charting capacity for ocean sustainability. Using the seven Science, Technology and Innovation Gender Objectives (STI GOs) of UNESCO’s SAGA (STEM and Gender Advancement) project, it reviews available information on women’s education and careers in ocean science for some of the countries with the highest numbers of ocean scientists in order to highlight STI GOs of concern. It also provides some information on resources for each STI GO to help institutions to achieve gender equality amongst their ocean science research staff.
Bayesian multivariate Beveridge–Nelson decomposition of I(1) and I(2) series with cointegration
Authors: Murasawa Yasutomo 
Published: June 2021

Abstract
The dynamic IS equation implies that if the real interest rate is I(1), then so is the output growth rate with possible cointegration, and log output is I(2). This paper extends the Beveridge–Nelson decomposition to such a case, and develops a Bayesian method to obtain error bands. The method is valid whether log output is I(1) or I(2). The paper applies the method to US data to estimate the natural rates (or their permanent components) and gaps of output, inflation, interest, and unemployment jointly, and finds that allowing for cointegration gives much bigger estimates of the gaps for all variables.
Effects of Eccentric Single-Leg Decline Squat Training Performed With Different Execution Times on Maximal Strength and Muscle Contraction Properties of the Knee Extensor Muscles
Authors: Abián-Vicén Javier , Martínez Fernando , Jiménez Fernando , Abián Pablo 
Published: June 2021

Abstract
Abián-Vicén, J, Martínez, F, Jiménez, F, and Abián, P. Effects of eccentric single-leg decline squat training performed with different execution times on maximal strength and muscle contraction properties of the knee extensor muscles. J Strength Cond Res 36(11): 3040–3047, 2022—The eccentric phase of the single-leg decline squat (SLDSe) has been described as a method to maximally load the knee extensor and has been used as an easy and effective rehabilitation exercise for patellar tendinopathy. The purpose of this study was to examine the impact of 6-week SLDSe training with 2 technical execution times on changes related to strength and muscle contractile properties. Thirty-six healthy volunteers were randomly divided into 3 groups: a control group (CG, n = 13, no training), a slow training group (n = 11, SLDSe in 6 seconds), and a fast training group (n = 12, SLDSe in 3 seconds). Subjects completed a 6-week SLDSe training program (80% of eccentric one repetation maximum [1RM]) 3 days a week. Pre, post, and 6-week follow-up of maximal dynamic and isometric strength and muscle contractile properties were assessed. After 6 weeks, training maximal loads showed a significant increase (p < 0.05) in 1RM of the SLDSe (∼92–95%), the concentric peak torque at 180°·s−1 (∼38%) and 60°·s−1 (∼25%), and the extension isometric peak torque (∼12%), with no differences between both experimental groups. Moreover, a decrease (p < 0.05) was found in the contraction time of the vastus medialis (VM) and the response time of the 3 analyzed quadriceps muscles. After the 6-week detraining period, there was a decrease in strength in all tests and in both experimental groups (1RM = 28–37%, isometric and isokinetic tests = 7–17%) and all contractile properties returned to baseline, except for the response time of the vastus lateralis in the fast training group and the contraction time of the VM in the STG. In conclusion, the SLDSe training protocol produced significant increases in muscle strength, showing important neuromuscular changes regardless of the technical execution time. It was also found that the training reduced the response and contraction time of the knee extensor musculature.
Simplified Prediction Method of Stress Intensity Factor in Mid-thick Plane in 3D Cracked Body and Its Difference from 2D Handbook Formula
Authors: Kawabata Tomoya , Kosuge Hiroaki , Ozawa Takumi , Mikami Yoshiki 
Published: June 2021

Abstract
The authors have been working to improve the crack tip opening displacement (CTOD) evaluation standard as a fracture parameter for the cleavage-type brittle fracture critical condition of carbon steel. In 2016, WES1108, Standard Test Method for Crack-Tip Opening Displacement (CTOD) Fracture Toughness Measurement, which is the CTOD test standard in Japan, was revised, and subsequently, the CTOD calculation formula of ISO 15653:2010, Metallic Materials – Method of Test for the Determination of Quasistatic Fracture Toughness of Welds, was revised in 2018, focusing on the study of the formula that constitutes the basis of the standard. Similar to the original British Standards equation, the proposed CTOD calculation formula consists of a small-scale yield (SSY) term and a plastic term, but in the SSY term, the two-dimensional (2D) stress intensity factor (SIF) is used. The authors focused on the incorrectness of this treatment derived from the difference between 2D and three-dimensional (3D). Here, two accurate relationships have been explored through systematic finite element method analyses; one is the correlation of the 3D SIF values in the mid-thickness plane and 2D SIF, and the second is the relationship between the actual 3D SIF in mid-thickness and the CTOD in mid-thickness. The KI ratio (K3D/K2D) sharply coincides with the value 1.11, as inferred in several previous pieces of research in the idealistic infinite plate with a crack. However, if the ligament size is finite as in the actual fracture toughness test, the KI ratio drops significantly from 1.11, and in some cases, the KI ratio is less than 1. By unifying these findings, a new precise CTOD formula has been established. Lastly, the study inferred that the error of the calculation formula is improved, especially in small thickness regions, as compared with the current standard proposed in 2016 and 2018 by the authors.
Sex disparities in COVID-19 outcomes of inpatients with diabetes: insights from the CORONADO study
Authors: Tramunt Blandine , Smati Sarra , Coudol Sandrine , Wargny Matthieu , Pichelin Matthieu , Guyomarch Béatrice , Al-Salameh Abdallah , Amadou Coralie , Barraud Sara , Bigot Edith , Bordier Lyse , Borot Sophie , Bourgeon Muriel , Bourron Olivier , Charrière Sybil , Chevalier Nicolas , Cosson Emmanuel , Fève Bruno , Flaus-Furmaniuk Anna , Fontaine Pierre , Galioot Amandine , Gonfroy-Leymarie Céline , Guerci Bruno , Lablanche Sandrine , Lalau Jean-Daniel , Larger Etienne , Lasbleiz Adèle , Laviolle Bruno , Marre Michel , Munch Marion , Potier Louis , Prevost Gaëtan , Renard Eric , Reznik Yves , Seret-Bégué Dominique , Sibilia Paul , Thuillier Philippe , Vergès Bruno , Gautier Jean-François , Hadjadj Samy , Cariou Bertrand , Mauvais-Jarvis Franck , Gourdy Pierre 
Published: June 2021

Objective
Male sex is one of the determinants of severe coronavirus diseas-e-2019 (COVID-19). We aimed to characterize sex differences in severe outcomes in adults with diabetes hospitalized for COVID-19.

Methods
We performed a sex-stratified analysis of clinical and biological features and outcomes (i.e. invasive mechanical ventilation (IMV), death, intensive care unit (ICU) admission and home discharge at day 7 (D7) or day 28 (D28)) in 2380 patients with diabetes hospitalized for COVID-19 and included in the nationwide CORONADO observational study (NCT04324736).

Results
The study population was predominantly male (63.5%). After multiple adjustments, female sex was negatively associated with the primary outcome (IMV and/or death, OR: 0.66 (0.49–0.88)), death (OR: 0.49 (0.30–0.79)) and ICU admission (OR: 0.57 (0.43–0.77)) at D7 but only with ICU admission (OR: 0.58 (0.43–0.77)) at D28. Older age and a history of microvascular complications were predictors of death at D28 in both sexes, while chronic obstructive pulmonary disease (COPD) was predictive of death in women only. At admission, C-reactive protein (CRP), aspartate amino transferase (AST) and estimated glomerular filtration rate (eGFR), according to the CKD-EPI formula predicted death in both sexes. Lymphocytopenia was an independent predictor of death in women only, while thrombocytopenia and elevated plasma glucose concentration were predictors of death in men only.

Conclusions
In patients with diabetes admitted for COVID-19, female sex was associated with lower incidence of early severe outcomes, but did not influence the overall in-hospital mortality, suggesting that diabetes mitigates the female protection from COVID-19 severity. Sex-associated biological determinants may be useful to optimize COVID-19 prevention and management in women and men.
Technical Writing as Tralanguage in Favor of a Translation and Productemiccompetence of the Word
Authors: Djelloul Said-Belarbi 
Published: June 2021

In translation and traductology, specialists recognize the undeniable relationship between the act of transiting, technical writing and the meaning of the words. However, considerations regarding the problems presented by culture and realia (untranslatable terms) in particular are frequent. It is at the same time the raison d’etre of translation and the source of difficulties. In other words, building a sense of a word or even producing it in case of a failure in the target language is not easy, but is this exercise impossible? If not, what should be done to overcome these pitfalls and cultural difficulties for realia via a translation operation in general and a legal one in particular? Answers to these questions can be found in a proposal entailing a strategic approach, calling on four major factors that the “trauthor” should take into account for the production of the meaning of a word. Finally, a reflection on said factors is made to access the process of ways of teaching for the production of word meaning.