bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intracranial Densitometry-Augmented Machine Learning Enhances the Prognostic Value of Brain CT in Pediatric Patients With Traumatic Brain Injury: A Retrospective Pilot Study
Authors: Kim Young-Tak , Kim Hakseung , Lee Choel-Hui , Yoon Byung C. , Kim Jung Bin , Choi Young Hun , Cho Won-Sang , Oh Byung-Mo , Kim Dong-Joo 
Published: November 2021

Background: The inter- and intrarater variability of conventional computed tomography (CT) classification systems for evaluating the extent of ischemic-edematous insult following traumatic brain injury (TBI) may hinder the robustness of TBI prognostic models.Objective: This study aimed to employ fully automated quantitative densitometric CT parameters and a cutting-edge machine learning algorithm to construct a robust prognostic model for pediatric TBI.Methods: Fifty-eight pediatric patients with TBI who underwent brain CT were retrospectively analyzed. Intracranial densitometric information was derived from the supratentorial region as a distribution representing the proportion of Hounsfield units. Furthermore, a machine learning-based prognostic model based on gradient boosting (i.e., CatBoost) was constructed with leave-one-out cross-validation. At discharge, the outcome was assessed dichotomously with the Glasgow Outcome Scale (favorability: 1–3 vs. 4–5). In-hospital mortality, length of stay (&gt;1 week), and need for surgery were further evaluated as alternative TBI outcome measures.Results: Densitometric parameters indicating reduced brain density due to subtle global ischemic changes were significantly different among the TBI outcome groups, except for need for surgery. The skewed intracranial densitometry of the unfavorable outcome became more distinguishable in the follow-up CT within 48 h. The prognostic model augmented by intracranial densitometric information achieved adequate AUCs for various outcome measures [favorability = 0.83 (95% CI: 0.72–0.94), in-hospital mortality = 0.91 (95% CI: 0.82–1.00), length of stay = 0.83 (95% CI: 0.72–0.94), and need for surgery = 0.71 (95% CI: 0.56–0.86)], and this model showed enhanced performance compared to the conventional CRASH-CT model.Conclusion: Densitometric parameters indicative of global ischemic changes during the acute phase of TBI are predictive of a worse outcome in pediatric patients. The robustness and predictive capacity of conventional TBI prognostic models might be significantly enhanced by incorporating densitometric parameters and machine learning techniques.
Storytelling as a Research Tool Used to Explore Insights and as an Intervention in Public Health: A Systematic Narrative Review
Authors: McCall Becky , Shallcross Laura , Wilson Michael , Fuller Chris , Hayward Andrew 
Published: November 2021

Objectives: Studies of storytelling (ST) used as a research tool to extract information and/or as an intervention to effect change in the public knowledge, attitudes, and behavior/practice (KAB/P) were sought and analyzed.Methods: Medline, EMBASE, PsycINFO, ERIC, Web of Science, Art and Humanities database, Scopus, and Google Scholar were searched, and a basic and broad quantitative analysis was performed, followed by an in-depth narrative synthesis of studies on carefully selected topics.Results: From this search, 3,077 studies were identified. 145 studies entered quantitative analysis [cancer and cancer screening (32/145), HIV (32/145), mental health (10/145), vaccination (8/145), and climate change (3/145)]. Ten studies entered final analysis [HIV/AIDs (5), climate change (1), sexual health (3), and croup (1)]. ST techniques included digital ST (DST), written ST, verbal ST, and use of professional writers. Of the ten studies, seven used ST to change KAB/P; the remainder used ST to extract insights. Follow-up and evaluation were very limited.Conclusion: ST reveals insights and serves as an intervention in public health. Benefits of ST largely outweigh the limitations, but more follow-up/evaluation is needed. ST should play a more significant role in tackling public health issues.PROSPERO registration number: CRD42019124704
Cohesin Mutations Induce Chromatin Conformation Perturbation of the H19/IGF2 Imprinted Region and Gene Expression Dysregulation in Cornelia de Lange Syndrome Cell Lines
Authors: Pileggi Silvana , La Vecchia Marta , Colombo Elisa Adele , Fontana Laura , Colapietro Patrizia , Rovina Davide , Morotti Annamaria , Tabano Silvia , Porta Giovanni , Alcalay Myriam , Gervasini Cristina , Miozzo Monica , Sirchia Silvia Maria 
Published: November 2021

Traditionally, Cornelia de Lange Syndrome (CdLS) is considered a cohesinopathy caused by constitutive mutations in cohesin complex genes. Cohesin is a major regulator of chromatin architecture, including the formation of chromatin loops at the imprinted IGF2/H19 domain. We used 3C analysis on lymphoblastoid cells from CdLS patients carrying mutations in NIPBL and SMC1A genes to explore 3D chromatin structure of the IGF2/H19 locus and evaluate the influence of cohesin alterations in chromatin architecture. We also assessed quantitative expression of imprinted loci and WNT pathway genes, together with DMR methylation status of the imprinted genes. A general impairment of chromatin architecture and the emergence of new interactions were found. Moreover, imprinting alterations also involved the expression and methylation levels of imprinted genes, suggesting an association among cohesin genetic defects, chromatin architecture impairment, and imprinting network alteration. The WNT pathway resulted dysregulated: canonical WNT, cell cycle, and WNT signal negative regulation were the most significantly affected subpathways. Among the deregulated pathway nodes, the key node of the frizzled receptors was repressed. Our study provides new evidence that mutations in genes of the cohesin complex have effects on the chromatin architecture and epigenetic stability of genes commonly regulated by high order chromatin structure.
An Efficient Chameleon Swarm Algorithm for Economic Load Dispatch Problem
Authors: Said Mokhtar , El-Rifaie Ali M. , Tolba Mohamed A. , Houssein Essam H. , Deb Sanchari 
Published: November 2021

Economic Load Dispatch (ELD) is a complicated and demanding problem for power engineers. ELD relates to the minimization of the economic cost of production, thereby allocating the produced power by each unit in the most possible economic manner. In recent years, emphasis has been laid on minimization of emissions, in addition to cost, resulting in the Combined Economic and Emission Dispatch (CEED) problem. The solutions of the ELD and CEED problems are mostly dominated by metaheuristics. The performance of the Chameleon Swarm Algorithm (CSA) for solving the ELD problem was tested in this work. CSA mimics the hunting and food searching mechanism of chameleons. This algorithm takes into account the dynamics of food hunting of the chameleon on trees, deserts, and near swamps. The performance of the aforementioned algorithm was compared with a number of advanced algorithms in solving the ELD and CEED problems, such as Sine Cosine Algorithm (SCA), Grey Wolf Optimization (GWO), and Earth Worm Algorithm (EWA). The simulated results established the efficacy of the proposed CSA algorithm. The power mismatch factor is the main item in ELD problems. The best value of this factor must tend to nearly zero. The CSA algorithm achieves the best power mismatch values of 3.16×10−13, 4.16×10−12 and 1.28×10−12 for demand loads of 700, 1000, and 1200 MW, respectively, of the ELD problem. The CSA algorithm achieves the best power mismatch values of 6.41×10−13 , 8.92×10−13 and 1.68×10−12 for demand loads of 700, 1000, and 1200 MW, respectively, of the CEED problem. Thus, the CSA algorithm was found to be superior to the algorithms compared in this work.
Characteristics of the Levels of Mechanisation in Arc Welding
Authors: Bagyinszki Gyula , Bitay Enikő 
Published: November 2021

Abstract
Improvement of quality, reduction of the subjective possibilities of faults may be facilitated with the help of the technically rational and economically justifiable mechanisation of productive serial production as well as the use of the wide range of hardware and software IT possibilities. Mechanisation is usually understood as the mechanisation of technological operations that may otherwise be performed by manual operations (human movements and effort). Mechanisation is therefore the substitution, in whole or in part, of manual labour with the help of specialised equipment and the mechanical operation of the various movements. The present article examines the particular features of mechanisation in the field of outstandingly high significance in industrial applications, i.e. arc welding, assisting the forms of training applied in the specialty area.
Producing a Dissimilar Joint of Copper to Austenitic Stainless Steel by Ultrasonic Welding
Authors: Márton Schramkó , Anna Kovács Tünde 
Published: November 2021

Abstract
There are several possibilities for establishing a cohesion joint between dissimilar metals. In the case of thin sheets, the ultrasonic welding process is suitable. This process can establish a cohesion joint rapidly, with a low heat input between the thin sheets. The authors have tried to determine the optimal ultrasonic welding parameters for copper and austenite stainless steel joining by using an experimental method of joining. Suitable results were obtained by welding tests due dissimilarities in the chemical, physical and mechanical properties of the copper and stainless steel. A standard size sheet thickness and test sample was used for the welding by different parameters. The parameters were refined based on the theoretical and practical knowledge during the experiments. The experimental welding was made by a Branson L20 type welder machine. The joint made by the different parameters was inspected by shearing-tensile tests (maximal force level).
Evaluation of Antifungal Activity of Carbonate Solvent – Part:1
Authors: Sathish M. , Seeniammal D. , Poornima R. , Rao J. Raghava 
Published: November 2021

Antimicrobial agents have been used in leather manufacturing to prevent leather products from microbial contamination. In this work, the antifungal activity of green solvent such as propylene carbonate was investigated against the mixed culture of fungi isolated from wet-blue using broth dilution/well diffusion. A concentration of 5% and above (propylene carbonate) showed effective antifungal activity against the mixed culture of fungi and the efficiency of propylene carbonate on the mixed culture increased with increasing concentration/volume. Propylene carbonate exhibited fungistatic activity against the mixed culture of fungi but it lost its activity after a certain period and fungal growth was observed again. It was also found that 2% propylene carbonate in chrome tanning process effectively inhibited the fungal growth and the wet-blue can be preserved up to 30 days without any fungal attack.
Envejecer en el actual contexto
Authors: Ludi María del Carmen 
Published: November 2021

El objetivo de esta presentación es compartir algunas reflexiones acerca la temática abordada desde nuestro trabajo en proyectos de Extensión e Investigación, donde identificamos: los modos de nombrar la vejez y a los sujetos portadores de la misma; los modos de ver, de nombrar, se plasman en modos de hacer; y los modos de hacer. Veneradas o despreciadas, amadas u odiadas, poderosas o miserables, como dice Kaplan (2001), las personas envejecidas han estado siempre presentes, tanto física como cultural y socialmente en todas las civilizaciones y culturas. Desde allí, nuestra apuesta principal en tantos años de trabajo con viejos, es mostrar la amplitud y complejidad del tema, su construcción como problemática y las implicancias del sentido de la vida.
Construyendo ámbitos de educación desde la Pedagogía: conocimiento de la educación y actividad común
Authors: Touriñán López José Manuel 
Published: November 2021

La educación es un ámbito de realidad susceptible de ser conocido, utilizando diversas formas de conocimiento. En el conocimiento de la educación se utilizan actualmente teorías filosóficas, teorías prácticas, investigaciones aplicadas y teorías sustantivas y se han generado ya términos propios con significación intrínseca a la educación.
Este trabajo insiste en la diferencia entre conocimiento de áreas culturales y conocimiento especializado y específico de la educación: el conocimiento pedagógico.
Se trata de formar criterio sobre la importancia de la Pedagogía en la construcción de ámbitos de educación. El conocimiento de la educación hace posible la construcción de ámbitos de educación con las áreas culturales, transformando la información en conocimiento y el conocimiento en educación. Hay que educar “con” el área cultural y esto exige ajustarse al significado de educar y ejercer la función pedagógica con competencia, estableciendo la relación educativa en la que el conocimiento de la educación y la actividad común son medios necesarios.
Veremos cómo la función pedagógica genera intervención desde las actividades comunes. Al ejecutar la actividad común externa, mejoramos y entrenamos las actividades-capacidades internas: sin la actividad es imposible educar con el área cultural y por medio de ella se hace posible que el educando sea agente actor y cada vez mejor agente autor de su propios proyectos y actos.
Sin el conocimiento de la educación no podemos construir ámbitos de educación y por tanto no podemos educar con el área cultural. Sin la actividad común es imposible educar y por medio de la relación educativa podemos lograr la concordancia entre valores educativos y sentimientos para hacer efectivo el paso del conocimiento a la acción en cada ámbito de educación construido.
Y así podremos concluir desde la Pedagogía que el conocimiento de la educación y la actividad común son medios necesarios de la relación educativa para educar con el área cultural en cada ámbito de educación construido.
Management of the C&D waste in the urban regeneration project
Authors: Giammetti Maria Teresa , Rigillo Marina 
Published: November 2021

This paper presents the first results of the research agreement signed by the Federico II University and CDP Immobiliare concerning reusing and recycling construction waste in the urban regeneration project. The research is aimed to develop a technical protocol for the ex-ante evaluation of the demolition operations, with a special focus on the criteria for picking the material samples to undergo chemical-physical analysis. The article is focused on the demolition process, implementing a BIM-based filing of the building system and aimed at a preliminary understanding of the material quantity, the material consistency and the state of conservation of the elements to be demolished. A tentative pre-characterisation, and an inventory of any contaminants present in the materials are also provided. In the form of discussion, further implications related the building characterisation and the planning of material flows with the reuse and recycle supply chains are provided as well.
The Influence of Family Leadership on Girl- Child School Dropout
Authors: Kamau Mary Wambui , Nyakwara Simon 
Published: November 2021

Family leadership is one of the vital aspects that influences and determines both the wellbeing and successful education of a girl-child. Unfortunately, the role of family leadership in ensuring girls' education is oversimplified into getting girls enrolled in school rather than warranting their perseverance in learning and successful completion. As a result, many communities in Tanzania, especially those in rural and marginalized areas are experiencing persistent girl–child school dropouts. It is against this standpoint that we sought to find out how family leadership may influence secondary school girls’ dropouts. We also explored possible measures which should be employed to eliminate girl-child school dropouts. In conducting this study, we employed a mixed research approach and convergent parallel design. We collected data through interviews and questionnaires involving 143 respondents including girl students, teachers, heads of schools, and district educational officers. Our findings from this study indicate that while the government of Tanzania has made remarkable efforts to ensure girls’ continuity and successful completion of secondary education, there are a number of factors hindering girls’ continuity and completion of secondary education. Weak family leadership, the improper raising of the children, less emphasis and interest on the importance of girls’ education, limited cooperation between family leadership were among the reason for continuous girl-child school dropout. Hence, based on our findings and the significance of girl’s education as well as the role which parents should play in ensuring girls achievement of education, we appeal to various educational leaders, to make strategic efforts in raising more awareness among rural and marginalized communities about the importance of educating girls and the role of family leadership in bringing to an end the phenomena of girl-child school dropout which is catastrophic to the long-awaited sustainable development. Moreover, we call upon all parents, to make intentional efforts in mentoring and influencing girls to strive towards achieving formal education
Effraction du psychisme chez les enfants victimes de violence sexuelle
Authors: Smida Samia 
Published: November 2021

Un grand nombre d’enfants sont victimes de violences graves et criminelles qui ont un impact psychotraumatique sur la mémoire des enfants et dont les conséquences sont directement liées à l’installation de troubles psychotraumatiques sévères. Ces troubles impactent la santé physique et psychique de ces enfants à court, moyen et long terme, en entraînant souvent des risques de suicide, de dépressions à répétition, d’anxiété, de phobies scolaires, d’angoisse de séparation, d’hyperactivité, d’irritabilité, de difficultés d’apprentissage, de conduites addictives, de troubles alimentaires, cognitifs et physiologiques. Quand on parle de traumatisme, on évoque généralement un événementiel, et plus particulièrement sa trace, c’est-à-dire son impact sur le fonctionnement psychique et sur sa mémoire. Une réflexion sur la notion de mémoire du traumatisme en lien avec celle de la résilience est proposée. A la lumière d’une vignette clinique la place du « temps de mémoire » est également mise en avant dans la dynamique du souvenir et de l’oubli ainsi que le destin des traumas infantiles qui ne peuvent être repris dans un processus d’après-coup.
La violence sexuelle dans le rapport à l’autorité. Prédation, victime, violences sexuelles, système
Authors: Bouvatier Thomas 
Published: November 2021

A propos des violences sexuelles, les médias s’intéressent souvent à la biographie des prédateurs, rarement à celle de leurs victimes. Parmi elles, se trouvent pourtant des femmes qui subissent de telles violences durant de longue période. Pourquoi et qu’est-ce que la psychanalyse peut en dire ? C’est ce que nous tâcherons de voir avec des cas cliniques, ainsi qu’à la lumière de Freud, Bourdieu, Racamier et Lacan.
Nouveaux « regards » psychocriminologiques sur le passage à l’acte et la perversion. À propos d’un cas « extrême »
Authors: Chagnon Jean-Yves 
Published: November 2021

A travers l’étude d’un meurtre ayant défrayé la chronique il y a quelques années par sa mise en acte / scène macabre (victimes homosexuelles enterrées vivantes, bâillonnées, en face à face), l’auteur soutient la perspective psychocriminologique psychanalytique « française ». Le passage à l’acte criminel a du sens au triple sens de signification, direction, sensorialité. Ces perspectives complexifient l’utilisation « aveuglante » du concept de perversion / perversité pour rendre compte de ce type de criminalité.
.”No One Can Give You Protection“ The Reversal of Protection in a Persian Decree Dated 562/1167
Authors: Azad Arezou , Firoozbakhsh Pejman 
Published: November 2021

While we know from historical texts that authorities in pre‑Mongol Iran and Central Asia issued letters of protection (amān‑nāma), no original has survived. In this article, we introduce one newly purchased document at the National Library of Israel catalogued as Ms.Heb.8333.86 and dated 562/1167, which refers to an act of protection (ḥimāyat)—or rather, its reversal. This is the closest we get to an actual documentary reference in Persian to an act of protection in the pre-Mongol period, and the document, therefore, merits closer study. The document offers an alternative history of protection far from the centres of power, at a very local level in the Ghūrid domains of today’s Central Afghanistan and northern India, and the survival of the document offers clues as to the longevity of acts of protection and their archival value. The study, by extension, highlights the dynamism of reciprocal loyalties between citizens and administrative officials in local communities.
الترجمة العربية لكتاب جالينوس «في تعرف علل الأعضاء الباطنة المعروف بكتاب المواضع الآلمة»: دراسة في تقنية الترجمة
Authors: بدر نشوى جمعة ضيف الله 
Published: November 2021

تناقش هذه الدراسة صحة نسبة الترجمة العربية لكتاب من كتب الطب اليوناني، وهو كتاب جالينوس «في تعرف علل الأعضاء الباطنة المعروف بالمواضع الآلمة» إلى المترجم حنين بن إسحاق العبادي (192/260-264هـ)، أشهر الأطباء في العصر العباسي؛ حيث اختلفت الآراء قديمًا وحديثًا حول صحة هذه النسبة، فالبعض ينسبها لحنين، والبعض ينسبها لتلميذه حبيش بن الحسن، ذلك أن أكثر ما ترجمه حبيش من اليونانية كان إلى العربية، وأن أكثر ما ترجمه حنين كان إلى السريانية. وستتم مناقشة هذه الإشكالية بالاستشهاد بمجموعة من الأمثلة، من مؤلفات وشروح لحنين، ثم مقارنتها باستشهادات مشابهة من ترجمة الكتاب؛ للوقوف على بعض الظواهر اللغوية والأسلوبية، التي يمكن من خلالها الاستدلال على المترجم. وسنفترض أن هذه الترجمة لحنين وفقًا لما جاء في النسخ المخطوطة للكتاب، وهي أكثر من عشرة، ونحاول تأييد ذلك الفرض بالأمثلة. وسنقارن ذلك ببعض الأمثلة مما ترجمه حبيش، وفقًا لما ذكره حنين نفسه في رسالته، وسيقوم منهج الدراسة على المقارنة والتحليل.
Factors predicting the perineural invasion in carcinoma oral cavity
Authors: Samanta Dipti R , Surendra Senapati , Suresh K Rout , Ajitesh Avinash , Maitree Parida , Tapas K Dash , Sanat K Bhuyan , Rabi N Mallik 
Published: November 2021

ABSTRACT

Objective:
This study to evaluate clinicopathological parameters such as age, tumor location, tumor size, grade, depth of invasion (DOI), lymphovascular space invasion (LVSI), lymph node metastasis, and stage that predict peri-neural invasion (PNI) in oral squamous cell carcinoma (OSCC).

Material and Methods:
A retrospective study on 1716 postoperative OSCC patients who satisfied the eligibility criteria and treated from January 2009 to December 2019 was analyzed using IBM SPSS V23. Mean and percentage were assessed using descriptive statistics. Wilcoxon–Mann–Whitney U-test was used to compare continuous variables, while Chi-square test was used to compare discrete variables between PNI-positive and PNI-negative groups. Two-tailed P < 0.05 was considered to be statistically significant.

Results:
Out of 1716 patients, 553 were PNI positive. The mean age was 48.76 ± 12.42 years in PNI-positive patients while 51.52 ± 12.51 years in PNI-negative patients. Males outnumbered females. The most common primary was carcinoma buccal mucosa (204, 36.9%), followed by carcinoma of oral tongue (161,29.1%). Maximum tumor size was 3.14 ± 1.20 cm in PNI-positive patients whereas 2.78 ± 1.22 cm in PNI-negative patients. Sixty (10.84%) patients in PNI-positive group and 51 (4.38%) in PNI-negative group had LVSI positive. Lymph node involvement was observed in 305 (55.13%) patients in PNI-positive group whereas 358 (30.78%) patients in PNI-negative group. Maximum number 228 (41.3%) in PNI-positive patients were in Stage IVA disease.

Conclusion:
PNI is one of the important adverse prognostic factors having a definite correlation with anatomical subsite, tumor size, grade, DOI, LVSI, lymph node involvement, and stage of the disease. PNI should be analyzed in postoperative histopathology report of OSCC that guides the clinician for adjuvant therapy.