bluuebunny/crossref_metadata_2025_split huggingface dataset:
Drive Pressure-Guided Individualized Positive End-Expiratory Pressure in Traumatic Brain Injury Surgery: A Randomized Controlled Trial
Authors: Chen Xiaoping , Wang Zi , Ge Yali , Gao Ju , Yang Liuqing 
Published: December 2024

AIM: Intraoperative lung-protective ventilation strategies (LPVS) have been shown to improve lung oxygenation and prevent postoperative pulmonary problems in surgical patients. However, the application of positive end-expiratory pressure (PEEP)-based LPVS in emergency traumatic brain injury (TBI) has not been thoroughly explored. The purpose of this study is to evaluate the effects of drive pressure-guided individualized PEEP on perioperative pulmonary oxygenation, postoperative pulmonary complications, and recovery from neurological injury in patients with TBI.
METHODS: A total of 111 TBI patients who met the inclusion criteria at Northern Jiangsu People's Hospital were randomized into three groups: group A (0 PEEP, 50% inhaled oxygen concentration, and 6 mL/kg tidal volume), group B (5 cmH2O PEEP, 50% inhaled oxygen concentration, and 6 mL/kg tidal volume), and group C (individualized PEEP guided by driving pressure, 50% inhaled oxygen concentration, and 6 mL/kg tidal volume). The primary endpoints were lung ultrasound score (LUS), optic nerve sheath diameter (ONSD), and serum levels of neuron-specific enolase (NSE) and High mobility group box 1 protein (HMGB1). Secondary endpoints included intraoperative hemodynamic and respiratory mechanics parameters, postoperative pulmonary complications, and clinical lung infection scores.
RESULTS: Eighty-nine patients completed the final analysis. LUS was significantly lower in group C compared to group A at T4 (least square mean [95% confidence interval (CI)]: 2.50 [1.35, 3.65] vs. 5.25 [4.10, 6.40], p < 0.05). Although ONSD increased gradually in group C, it did not differ substantially from group A postoperatively (least square mean [95% CI]: 5.09 [4.90, 5.27] vs 5.16 [4.97, 5.34] mm, p > 0.05). Serum NSE levels in group C were significantly lower on postoperative days 1 (4.40 [3.89, 4.41] vs. 10.95 [10.44, 11.46], p < 0.05) and 3 (2.79 [2.28, 3.30] vs. 10.95 [10.44, 11.46], p < 0.05). Additionally, serum HMGB1 levels in group C were significantly reduced on postoperative days 1 (229 [200, 258] vs. 662 [633, 691], p < 0.05) and 3 (166 [137, 195] vs. 662 [633, 691], p < 0.05).
CONCLUSIONS: Individualized PEEP guided by driving pressure can improve perioperative pulmonary oxygenation and reduce the incidence of postoperative pulmonary complications. Furthermore, this strategy did not significantly elevate intraoperative intracranial pressure (ICP) and promoted recovery from postoperative neurological injury, likely by reducing the inflammatory response.
CLINICAL TRIAL REGISTRATION: https://www.chictr.org.cn/ (clinical trial no. ChiCTR2200066795).
Jaw Growth and Development in Class II Division I Malocclusion Children Using the Myobrace® Muscle Function Appliance
Authors: He Meiying , Hu Wenqi , Zhang Yan , Jiang Weijie 
Published: December 2024

AIM: Class II Division I malocclusion is common in pediatric orthodontics, and is often associated with malocclusion and poor muscle functionality. However, research on post-treatment changes in maxillomandibular dimensions, excluding normal development influences, is limited. Therefore, this study aimed to investigate the effects of Myobrace® appliance and targeted muscle functional training on maxillomandibular dimensions in children with Class II Division I malocclusion, compared to directed oral muscle training alone.
METHODS: This retrospective study included 96 children with Class II Division I malocclusion. Based on the treatment method, the patients were divided into two groups: the treatment group (patients who underwent treatment with the Myobrace® muscle function appliance combined with directed muscle functional training for one year) and the control group (patients who received only directive oral muscle training for one year). The growth changes in jaws in both groups were assessed through X-ray cephalometry and plaster casting.
RESULTS: The Sella-Nasion to A point angle (SNA) had increased (p > 0.05), and the maxilla length increased, with significant differences between the two groups (p < 0.05). Furthermore, after intervention, there was a significant increase in mandibular length (p < 0.05). There was a slight decrease in the S-Co value indicating the position of the mandibula. However, this change was not significant, indicating that the mandibula didn't move forward after treatment. The angle between the Frankfort Horizontal Plane and mandibular planes (MP-FH) increased after treatment (p > 0.05), and there were increasing trends on the Y axis, posterior heights, and anterior heights, and these changes were statistically significant (p < 0.05). Additionally, we observed a significant increase in the dental arch (p < 0.05) in the treatment group compared to the control group. This finding suggested that the Myobrace® appliance can promote dental arch growth.
CONCLUSIONS: Myobrace® appliance effectively boosts dental arch growth while correcting Class II Division I malocclusion. However, it may be limited in cases of Class II Division I with high-angle, maxillary protrusion, or severe mandibular retrusion, emphasizing the significance of assessing patient characteristics to ensure optimal improvement.
The Long-Term Prognostic Outcomes of Emergent Colon Cancer Surgery: A Single-Center Experience
Authors: Yazıcı Hilmi , Esmer Ahmet Cem , Vila Frenki , Yeğen Cumhur 
Published: December 2024

AIM: Colorectal cancer (CRC) ranks as the second most diagnosed and third most deadly cancer worldwide. Despite advances in early diagnosis and treatment, CRC remains a leading cause of cancer-related deaths. Up to 30% of CRC patients are diagnosed during emergency department visits, leading to surgical procedures that may not adhere to oncological principles due to complications like obstruction, bleeding, or perforation. This study aims to compare postoperative complications and long-term oncological outcomes between emergent and elective colon cancer surgeries.
METHODS: Retrospective analysis was performed on patients who underwent surgery for colonic adenocarcinoma from January 2018 to December 2021. Patients included were those diagnosed with colonic adenocarcinoma, excluding those under 18 years old or with other pathological results. Patients were examined under the elective and emergent surgery groups. The study investigated demographic data, tumor localization, operation type, postoperative complications, and long-term oncological outcomes. A Cox proportional hazard model was used to perform multivariate analysis in order to identify prognostic variables for overall survival (OS) and disease-free survival (DFS).
RESULTS: A total of 318 patients were included, with 62 undergoing emergent surgery and 256 undergoing elective surgery. Patient demographics were similar between the groups. The emergent surgery group had a significantly lower OS rate at 50 months compared to the elective surgery group (51% vs. 62%, p = 0.002). DFS at 50 months was also lower for the emergent surgery group compared to the elective surgery group (43% vs. 59%), but this difference did not reach statistical significance (p = 0.202). Independent poor prognostic factors included stage N, stage M, tumor diameter, neural invasion, and emergent surgery status.
CONCLUSIONS: Emergency surgery for colon cancer is associated with poor long-term outcomes due to shorter OS and DFS, highlighting the need for increased awareness and screening to reduce emergency colon cancer surgery.
Scrotal Gangrene Secondary to Staphylococcus Aureus Infection: A Case Report
Authors: Zheng Jianhong , Alhaskawi Ahmad , Dong Yanzhao , Zhou Haiying , Abdalbary Sahar Ahmed , Lu Hui 
Published: December 2024

AIM: To present a case of scrotal gangrene secondary to Staphylococcus aureus infection, highlighting the importance of early intervention and multidisciplinary care in the management of Fournier's gangrene.
CASE PRESENTATION: This case report details the clinical course of a 67-year-old male who presented with severe perineal pain and swelling, later diagnosed as Fournier's gangrene due to Staphylococcus aureus infection. The patient underwent emergency surgical debridement and received antibiotic therapy. Postoperative care included wound cleaning, pain management, and continuous monitoring of clinical and laboratory parameters.
RESULTS: The patient showed significant improvement post-surgery, with a marked decrease in white blood cell (WBC) count and C-reactive protein levels, as well as normalization of body temperature. A successful second-stage wound debridement and closure were performed, and the patient experienced no major complications during recovery. The patient reported minimal pain postoperatively and improved daily functioning, contributing to an enhanced quality of life.
CONCLUSIONS: This case underscores the critical importance of early aggressive treatment and comprehensive multidisciplinary care in managing Fournier's gangrene. Prompt surgical intervention combined with effective postoperative management can lead to positive outcomes, with significant improvement in clinical and laboratory parameters, enhanced patient comfort, and improved quality of life. Further research is needed to optimize treatment protocols and improve outcomes in similar cases.
An Analysis of Operated Mediastinal Cysts and Masses
Authors: Özdemir Çiflik Büşra , Çiflik Kadir Baturhan , Akkaş Yücel , Yekeler Erdal , Koçer Bülent , Karaoğlanoğlu Nurettin 
Published: December 2024

AIM: This study had two aims: to analyze surgical patients with mediastinal cysts and masses according to clinical, histopathological, and surgical types; and compare the impact of the coronavirus disease 2019 (COVID-19) pandemic on these cases.
METHODS: A retrospective analysis was conducted on 132 patients who had undergone surgical intervention for mediastinal cysts and masses. Demographic, clinical, and histopathologic data were recorded. Patients were divided into two groups based on their preference for video-assisted thoracoscopic surgery (VATS) and other surgical methods. Patients who had undergone surgery during and before the COVID-19 pandemic were also compared.
RESULTS: Lesions were detected incidentally in 56 patients (42.4%). The lesions were most commonly located in the anterior mediastinum (n = 86, 65.2%), while the most common pathology was found to be thymoma (n = 47, 35.6%). VATS was the most preferred method of operation (n = 36, 27.3%). The duration of hospital stay was observed to be statistically significantly shorter in patients who underwent VATS (p = 0.016). After the COVID-19 pandemic, the incidental incidence of mediastinal cysts and masses was significantly higher (p = 0.005).
CONCLUSIONS: The incidental detection rate of operated mediastinal cysts and masses increased after the COVID-19 pandemic. It is suggested that this study act a starting point for investigating the impact of the pandemic on mediastinal cysts and masses.
Cytoreductive Surgery Combined with Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Colorectal Cancer Peritoneal Metastasis: A Systematic Review and Meta-Analysis
Authors: Peng Wei , Li Jianhong , Jin Chengwu , Liu Heng , Wang Mingju , Lu Jing 
Published: December 2024

AIM: This research aimed to evaluate the long-term survival rates and relapse-free status of colorectal cancer (CRC) patients with peritoneal metastases who underwent cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC). The data are expected to provide valuable insights for determining therapeutic options for these patients.
METHODS: PubMed (MEDLINE), Embase, Web of Science, Cochrane, Ovid, Scopus, and ClinicalTrials.gov databases were searched from inception to 1 August 2023, without language restrictions. The primary outcomes of interest were overall survival (OS) and relapse-free survival/disease-free survival (RFS/DFS), while the secondary outcome was complications. Fourteen studies were included in both qualitative and quantitative analyses.
RESULTS: Analyses of the 14 included publications (10 cohort studies and 4 randomized controlled trials) indicated significantly higher OS and RFS/DFS rates in the CRS + HIPEC group compared to the control group regimens.
CONCLUSIONS: Individuals with peritoneal metastases following a diagnosis of CRC may have improved survival outcomes when treated with CRS + HIPEC.
SYSTEMATIC REVIEW REGISTRATION: PROSPERO: CRD42023470622.
Application of Osborne's Ligament Suspension and Ulnar Nerve Anterior Transposition in Conjunction with Transcutaneous Electrical Nerve Stimulation for Managing Cubital Tunnel Syndrome: A Retrospective Study
Authors: Wang Wei , Tian Yu , Zhou Gang-gang , Deng Jian-feng , Li Wen-yan , Wang Rui 
Published: December 2024

AIM: To explore the effectiveness and safety of Osborne's ligament suspension and ulnar nerve anterior transposition (OLSUNAT) in conjunction with transcutaneous electrical nerve stimulation (TENS) for managing cubital tunnel syndrome (CTS).
METHODS: A total of 116 individuals diagnosed with CTS who underwent OLSUNAT in our hospital between October 2020 and December 2023 were retrospectively selected. They were divided into a treatment group (62 cases) and a control group (54 cases) based on whether they received subsequent TENS. Observation indicators included pain level, numbness, ulnar nerve conduction velocity, strength of the abductor of the little finger, two-point discrimination, elbow range of motion, fine motor activities of the upper limb and hand, SF-36 scores, and incidence of complications.
RESULTS: No significant differences in baseline characteristics were identified between the treatment and control groups (p > 0.05). After treatment, both groups showed remarkable improvements in pain level, numbness, motor nerve conduction velocity (MCV), sensory nerve conduction velocity (SCV), strength of the abductor of the little finger, two-point discrimination, elbow range of motion, Simple Test for Evaluating Hand Function (STEF) score, and SF-36 scores compared to before treatment (p < 0.05). However, the treatment group showed greater progress than the control group (p < 0.05). Although the overall incidence of complications in the treatment group was slightly lower than in the control group, this difference did not reach statistical significance (p > 0.05).
CONCLUSIONS: OLSUNAT combined with TENS offers significant advantages in managing CTS, effectively alleviating symptoms, promoting nerve and elbow function recovery, and improving patients' quality of life while demonstrating high safety. However, further extensive and long-term studies are needed to confirm its sustained efficacy and safety.
КАЗАХСКИЕ ИГРУШКИ-КУКЛЫ ИЗ ФОНДОВ МУЗЕЯ АНТРОПОЛОГИИ И ЭТНОГРАФИИ ИМ. ПЕТРА ВЕЛИКОГО (КУНСТКАМЕРА) РАН
Authors: Стасевич Инга 
Published: December 2024

St. Petersburg Kunstkamera item collections devoted to Kazakh traditional culture comprise 49 dolls. They are all dated late 19th — 1st half of the 20th centuries. Some of the dolls are, as it were, schematic, others, on the contrary, are made with care to detail, their miniature clothes reproducing not only the composition of the costume and its cut, but also its decorative elements, which allows to define who a certain doll represents: a maiden, a young married woman, a middle‑aged woman, a groom, or a child. The article aims to introduce these museum pieces as an ethnographic source for scientific use. The author describes the design features, the dolls' costumes, and their role in Kazakh every‑day and ritual culture.
Insinuation in the View Talk Show: A Cognitive Discourse Analysis
Authors: Kareem Hussein Hamid , Kadhim Sadiq Mahdi 
Published: December 2024

This study is about the insinuation in the View talk show from the cognitive discourse perspective. It aims to show how lack of knowledge can affect the way people talk to each other. This is conducted by the aid of an eclectic model of Johnson’s Conceptual Metaphor (1980), and Sharfian’s Cultural Cognition ( 2011 ). The data is collected from the episodes on You Tube from an American talk show called the View. It is concluded that insinuation is a process of indirect communication that is done according to some strategies for many purposes, among them is to avoid social embarrassment.
Factores asociados a brote por Clostridium difficile en el Hospital Nacional de Geriatría y Gerontología, Costa Rica
Authors: Bonilla Vargas Alice , Paniagua Hidalgo Diana , Leandro Astorga Gustavo , Abarca Gómez Leandra , Badilla Vargas Xiomara 
Published: December 2024

Antecedentes: el objetivo de este estudio fue determinar los factores asociados que influyeron en el brote por Clostridium difficile en el Hospital Nacional de Geriatría y Gerontología, Costa Rica, de agosto a diciembre de 2014.
Metodología: se realizó un estudio de casos y controles. Se definió como caso a todo paciente hospitalizado con resultado positivo para Clostridium difficile entre agosto y diciembre de 2014 y un control paciente para aquellos que no presentaron diarrea. Las exposiciones a comorbilidad y a los tratamientos se dieron para el grupo infectado en un periodo de ventana de tres semanas antes del inicio de los síntomas y para el grupo de control de tres semanas antes del egreso.
Resultados: la edad media de los casos fue de 85 años (DE= 7,4) y de los pacientes control de 83 (DE= 7,9). El OR ajustado mostró que el Clostridium difficile se asoció con afecciones médicas subyacentes a la enfermedad por ácido péptico [OR 74,0; intervalo de confianza (IC) 95 %: 3,9-1 377,0, p= 0,00], a cardiopatía (OR 6,9; IC 95 %: 1,1-43,3, p= 0,03) y al uso de la sonda nasogástrica (OR 63,8; IC 95 %: 14,9-1 386,3, p= 0,00). El modelo ajustado fue la administración de cefotaxima (OR 591,7; IC 95 %: 36,0-9 709,2, p <0,00), de ceftazidima (OR 10; IC 95 %: 3,8-18,1, p <0,03) y de ampicilina (OR 119,7, IC 95 %: 7,9-18 002,9, p <0,03).
Conclusión: se determinó que el brote por Clostridium difficile se asoció al uso de ciertos antibióticos, al sexo masculino, al uso de sonda nasogástrica, al subregistro de notificación obligatoria y a la comorbilidad de enfermedad ácido-péptica y cardiopatía.
Comportamento de bovinos fistulados e canulados no rúmen, em confinamento
Authors: Fuzaro Heloisa Couto , Fuzaro Letícia Couto , Zeferino Cynthia Pieri , Soares Vando Edésio , Leal do Carmo Victor Gomes Leal do Carmo , Marques Pereira Kaike José , Brennecke Käthery 
Published: December 2024

A fistulação é um procedimento cirúrgico que cria uma abertura no trato digestório do animal, permitindo acesso direto ao órgão para estudos e manejo nutricional. Apesar de sua ampla utilização em pesquisas, há relatos de que bovinos fistulados podem apresentar alterações comportamentais, como redução no consumo de alimentos e preferência por itens de maior digestibilidade. No entanto, o impacto desse procedimento no comportamento geral dos animais, incluindo aspectos como interação social, reatividade, ruminação e padrões de repouso, ainda não está totalmente esclarecido, especialmente em condições específicas de manejo, como o confinamento. Essas lacunas evidenciam a necessidade de estudos mais detalhados que considerem fatores ambientais e sociais que possam influenciar o comportamento desses animais. O objetivo deste experimento foi observar o comportamento de cinco bovinos machos, nelore, fistulados e canulados no rúmen, em confinamento. As observações foram realizadas in locu, com registros a cada 10 minutos, nos meses de dezembro a abril, utilizando planilhas baseadas em etogramas comportamentais. Os dados foram convertidos em valores quantitativos e analisados por estatística descritiva. Os resultados indicaram maior frequência de comportamento em pé entre dezembro e fevereiro, e maior reatividade nos meses de dezembro, março e abril. De modo geral, a distribuição das atividades comportamentais observadas esteve dentro do esperado para bovinos, indicando adaptação adequada ao sistema de confinamento.
Pelatihan Membuat Presentasi Menarik Menggunakan Canva Untuk Anggota Penyuluh Agama Buddha Provinsi Banten
Authors: Halim Ardie , Yo Ceng Giap  , Raditya Rimbawan O  , Wiyono  , Andri Wijaya  , Aditiya Hermawan  , Jessen Laorenza Suwandi  , Arvin Lawistra  
Published: December 2024

Pengabdian kepada masyarakat (PkM) yang dilakukan oleh tim dosen dan mahasiswa Fakultas Sains dan Teknologi Universitas Buddhi Dharma, Tangerang bertujuan untuk memberikan pelatihan dalam membuat materi pembelajaran secara interaktif dan inovatif menggunakan media berbasis digital canva kepada anggota penyuluh agama Buddha (PAH) agar dapat membuat materi ceramah yang sesuai dengan cara yang interaktif dan inovatif. Metode yang digunakan dalam PkM ini adalah demontrasi (peragaan), praktikum (membuat materi ceramah secara langsung menggunakan komputer di laboratoriom komputer Universitas Buddhi Dharma) dan studi kasus (latihan mandiri membuat materi presentasi yang dipandu oleh tutor). Hasil PkM ini adalah para anggota PAH dapat memperoleh pemahaman dan pengetahuan tentang cara membuat slide presentasi dalam beberapa bentuk seperti teks, gambar, audio, video dengan menggunakan canva, sehingga akan mempermudah dalam penyampaian materi ceramah. Hal ini terlihat dari hasil kuesioner dengan persentase 74% peserta sangat setuju bahwa materi yang disampaikan sangat bermanfaat dan dapat dipraktekkan untuk mendukung pembuatan materi presentasi
Pemanfaatan Microsoft Office bagi Perangkat Desa dalam Membantu Pelayanan Warga
Authors: Ibrahim Anton Maulana , Khumaiya Nabila 
Published: December 2024

Program pengabdian masyarakat ini bertujuan untuk meningkatkan keterampilan perangkat desa dalam menggunakan Microsoft Office, terutama aplikasi Microsoft Word dan Excel, guna meningkatkan efisiensi pelayanan administrasi kepada warga. Pelatihan dilaksanakan melalui metode tatap muka yang meliputi penyampaian materi, diskusi, dan praktik langsung. Sebelum pelatihan, banyak perangkat desa menghadapi kesulitan dalam menggunakan aplikasi ini, yang menghambat proses administrasi. Setelah pelatihan, terdapat peningkatan signifikan dalam keterampilan peserta, yang terlihat dari hasil evaluasi pre-test dan post-test. Program ini juga meningkatkan kesadaran perangkat desa akan pentingnya literasi digital dalam menjalankan tugas sehari-hari. Dengan peningkatan kemampuan ini, diharapkan perangkat desa dapat memberikan pelayanan yang lebih efektif dan efisien kepada masyarakat.
Structural Investigations of Some Metal Complexes of Malon-Di-(α-Naphthyl) Amide-Oxime
Authors: Shrivastava Mukesh , Swarnabala G. , Khatavkar S. B. , Sadana G. S. , Bharadwaj Anahita 
Published: December 2024

The study investigates the structural properties of Cu(II), Ni(II), Fe(II), Co(III), Zn(II), Cd(II), and Hg(II) complexes with malon-di-(α-naphthyl)amide-oxime (isonitroso malon-di-(α-naphthyl)amine oxime). It summarizes chemicals, equipment, experimental methods, metal-ligand bonding, stereochemistry, oxidation states, and coordination modes using spectral and magnetic data. Solution studies done with reagent and metal salts assisted in predicting geometry for these complexes, to finalize the M:L ratios and have allowed the pH to be established to separate the complex formed in solid state. The green Cu(II) complex is dimeric, confirmed by its electronic and reflectance spectra, with a likely square planar structure, Bleaney-Bower’s equation helped to finalize the dimeric complex formation. Yellow Ni(II) and dark-blue Fe(II) complexes are paramagnetic, suggesting high-spin octahedral geometries. The dark-red Co(III) complex exhibits weak paramagnetism, explained by the Van Vleck term, spectral data, and its diamagnetic nature, indicative of an octahedral structure. Zn(II), Cd(II), and Hg(II) complexes are assigned tetrahedral structures based on magnetic and infrared spectral data. From the dark colours of the complexes obtained, they may be utilized as complexing agents like the well-known oxime containing ligands.