bluuebunny/crossref_metadata_2025_split huggingface dataset:
Observing black holes through superconductors
Authors: Kaku Youka , Murata Keiju , Tsujimura Jun 
Published: September 2021

Abstract
We propose a way to observe the photon ring of the asymptotically anti-de Sitter black hole dual to a superconductor on the two-dimensional sphere. We consider the electric current of the superconductor under the localized time-periodic external electromagnetic field. On the gravity side, the bulk Maxwell field is sent from the AdS boundary and then diffracted by the black hole. We construct the image of the black hole from the asymptotic data of the bulk Maxwell field that corresponds to the electric current on the field theory side. We decompose the electric current into the dissipative and non-dissipative parts and take the dissipative part for the imaging of the black hole. We investigate the effect of the charged scalar condensate on the image. We obtain the bulk images that indicate the discontinuous change of the size of the photon ring.
Litter Quality Is a Stronger Driver than Temperature of Early Microbial Decomposition in Oligotrophic Streams: a Microcosm Study
Authors: Pérez Javier , Ferreira Verónica , Graça Manuel A. S. , Boyero Luz 
Published: September 2021

AbstractLitter decomposition is an ecological process of key importance for forest headwater stream functioning, with repercussions for the global carbon cycle. The process is directly and indirectly mediated by microbial decomposers, mostly aquatic hyphomycetes, and influenced by environmental and biological factors such as water temperature and litter quality. These two factors are forecasted to change globally within the next few decades, in ways that may have contrasting effects on microbial-induced litter decomposition: while warming is expected to enhance microbial performance, the reduction in litter quality due to increased atmospheric carbon dioxide and community composition alteration may have the opposite outcome. We explored this issue through a microcosm experiment focused on early microbial-mediated litter decomposition under stream oligotrophic conditions, by simultaneously manipulating water temperature (10 °C and 15 °C) and litter quality (12 broadleaf plant species classified into 4 categories based on initial concentrations of nitrogen and tannins). We assessed potential changes in microbial-mediated litter decomposition and the performance of fungal decomposers (i.e., microbial respiration, biomass accrual, and sporulation rate) and species richness. We found stronger effects of litter quality, which enhanced the performance of microbial decomposers and decomposition rates, than temperature, which barely influenced any of the studied variables. Our results suggest that poorer litter quality associated with global change will have a major repercussion on stream ecosystem functioning.
Radiomics for detecting prostate cancer bone metastases invisible in CT: a proof-of-concept study
Authors: Hinzpeter Ricarda , Baumann Livia , Guggenberger Roman , Huellner Martin , Alkadhi Hatem , Baessler Bettina 
Published: September 2021

Abstract

Objectives
To investigate, in patients with metastatic prostate cancer, whether radiomics of computed tomography (CT) image data enables the differentiation of bone metastases not visible on CT from unaffected bone using 68 Ga-PSMA PET imaging as reference standard.

Methods
In this IRB-approved retrospective study, 67 patients (mean age 71 ± 7 years; range: 55–84 years) showing a total of 205 68 Ga-PSMA-positive prostate cancer bone metastases in the thoraco-lumbar spine and pelvic bone being invisible in CT were included. Metastases and 86 68 Ga-PSMA-negative bone volumes in the same body region were segmented and further post-processed. Intra- and inter-reader reproducibility was assessed, with ICCs < 0.90 being considered non-reproducible. To account for imbalances in the dataset, data augmentation was performed to achieve improved class balance and to avoid model overfitting. The dataset was split into training, test, and validation set. After a multi-step dimension reduction process and feature selection process, the 11 most important and independent features were selected for statistical analyses.

Results
A gradient-boosted tree was trained on the selected 11 radiomic features in order to classify patients’ bones into bone metastasis and normal bone using the training dataset. This trained model achieved a classification accuracy of 0.85 (95% confidence interval [CI]: 0.76–0.92, p < .001) with 78% sensitivity and 93% specificity. The tuned model was applied on the original, non-augmented dataset resulting in a classification accuracy of 0.90 (95% CI: 0.82–0.98) with 91% sensitivity and 88% specificity.

Conclusion
Our proof-of-concept study indicates that radiomics may accurately differentiate unaffected bone from metastatic bone, being invisible by the human eye on CT.

Key Points
• This proof-of-concept study showed that radiomics applied on CT images may accurately differentiate between bone metastases and metastatic-free bone in patients with prostate cancer.
• Future promising applications include automatic bone segmentation, followed by a radiomics classifier, allowing for a screening-like approach in the detection of bone metastases.
An evaluation of short-term outcomes after reoperations for anastomotic leakage in colon cancer patients
Authors: Warps A. K. , Dekker J. W. T. , Tanis P. J. , Tollenaar R. A. E. M. 
Published: September 2021

Abstract
Purpose
Scarce data are available on differences among index colectomies for colon cancer regarding reoperation for anastomotic leakage (AL) and clinical consequences. Therefore, this nationwide observational study aimed to evaluate reoperations for AL after colon cancer surgery and short-term postoperative outcomes for the different index colectomies.

Methods
Patients who underwent resection with anastomosis for a first primary colon carcinoma between 2013 and 2019 and were registered in the Dutch ColoRectal Audit were included. Primary outcomes were mortality, ICU admission, and stoma creation.

Results
Among 39,565 patients, the overall AL rate was 4.8% and ranged between 4.0% (right hemicolectomy) and 15.4% (subtotal colectomy). AL was predominantly managed with reoperation, ranging from 81.2% after transversectomy to 92.4% after sigmoid resection (p < 0.001). Median time to reoperation differed significantly between index colectomies (range 4–8 days, p < 0.001), with longer and comparable intervals for non-surgical reinterventions (range 13–18 days, p = 0.747). After reoperation, the highest mortality rates were observed for index transversectomy (15.4%) and right hemicolectomy (14.4%) and lowest for index sigmoid resection (5.6%) and subtotal colectomy (5.9%) (p < 0.001). Reoperation with stoma construction was associated with a higher mortality risk than without stoma construction after index right hemicolectomy (17.7% vs. 8.5%, p = 0.001). ICU admission rate was 62.6% overall (range 56.7–69.2%), and stoma construction rate ranged between 65.5% (right hemicolectomy) and 93.0% (sigmoid resection).

Conclusion
Significant differences in AL rate, reoperation rate, time to reoperation, postoperative mortality after reoperation, and stoma construction for AL were found among the different index colectomies for colon cancer, with relevance for patient counseling and perioperative management.
Temporal fluctuations of post-tonsillectomy haemorrhage
Authors: Grasl Stefan , Mekhail Patrick , Janik Stefan , Grasl Christoph M. , Vyskocil Erich , Erovic Boban M. , Arnoldner Christoph , Landegger Lukas D. 
Published: September 2021

AbstractPurposeAlthough haemorrhage is a common and in some cases life-threatening complication after tonsillectomy, surprisingly little is known about the temporal fluctuations of the onset of bleeding. The purpose of this study was to assess circadian and seasonal rhythms of post-tonsillectomy haemorrhage (PTH) and potential ramifications to educate patients and health care staff.MethodsThis retrospective study carried out at a tertiary referral hospital included paediatric and adult patients requiring emergency surgery due to severe PTH between 1993 and 2019. Medical records were reviewed and patient demographics, details regarding the initial procedure, postoperative day of haemorrhage, and start time of emergency surgery were extracted. Descriptive statistics, Kruskal–Wallis test, Mann–WhitneyUtest, and Chi-square goodness of fit tests were used to detect potential differences.ResultsA total of 300 patients with severe PTH and subsequent emergency surgery were identified. The median postoperative duration until PTH was 6 (range: < 1–19) days. 64.7% (n = 194) of all emergency surgeries had to be performed during evening and night hours (6 pm—6 am) (p < 0.0001). Compared to diurnal incidents, the risk of a nocturnal PTH event increased, the longer ago the initial surgery was (p < 0.0001). No seasonal variations were identified. Age, sex, and details of the initial procedure had no significant influence on the start time according to the surgical protocol.ConclusionThe discovered temporal fluctuations of PTH are of relevance for patient awareness and preoperative education. Due to possible life-threatening complications, management of severe PTH requires specific resources and trained medical staff on call.
Eco-efficiency of system alternatives of the urban water-energy-waste nexus
Authors: Poganietz Witold-Roger , Friedrich Jasmin , Lehn Helmut 
Published: September 2021

AbstractWastewater systems in developed cities contribute significantly to public health. The related systems are energy and resource intensive and do not recover nutrients in an efficient and effective way. Separating wastewater to greywater and blackwater at the source and exploiting organic municipal solid waste as an additional feed to an adjunct biogas plant could support efforts to make use of the potentials to reduce the environmental impacts, to increase the energy efficiency of winning nutrients, and to implement an additional, locally available energy source. However, the implementation of such systems is seen as expensive.The overarching aim of the paper is to analyze the eco-efficiency of transforming the current separately organized wastewater-energy-waste systems to an integrated one. The study differs between three system alternatives. The least invasive system change assumes a separation of wastewater at the source without a complete overhaul of the current system; the most elaborated one takes the current wastewater system fully out of operation. The reference for the current system is the existing system of a German medium-sized urban neighborhood. The analysis considers the eco-efficiency of two resource-related (fossil and metal depletion) and three emissions-related (climate change, photochemical oxidant formation and terrestrial acidification) impacts.Under the conditions of the settlement investigated, a transformation to the system alternatives will generate in all cases a weak eco-efficiency, i.e. the higher costs of implementing a new system counteracts with the noteworthy environmental improvement. Of the three options, the most elaborated one sees the best performance.
Minding the Gaps in Fish Welfare: The Untapped Potential of Fish Farm Workers
Authors: Medaas Christian , Lien Marianne E. , Gismervik Kristine , Kristiansen Tore S. , Osmundsen Tonje , Størkersen Kristine Vedal , Tørud Brit , Stien Lars Helge 
Published: September 2021

AbstractThe welfare of farmed fish is often regarded with less concern than the welfare of other husbandry animals, as fish are not universally classified as sentient beings. In Norway, farmed fish and other husbandry animals are legally protected under the same laws. Additionally, the legislature has defined a number of aquaculture-specific amendments, including mandatory welfare courses for fish farmers who have a key role in securing animal welfare, also with regards to noting welfare challenges in the production process. This article uses fish welfare courses as a site from which to inquire about the common-sense understanding of fish welfare in Norwegian fish farming. The focus is specifically on fish farm employees, their experiences of welfare-related issues and contradictions in their daily work, and the struggle to act responsibly in aquaculture settings. Through participant observation at welfare courses, as well as interviews and conversations with fish farm workers, the article details how challenges are experienced ‘on the ground’, and suggests how fish farm workers’ own experiential knowledge might be mobilized to improve the general welfare of farmed fish.
Analysis of AC Transport Loss in Conductor on Round Core Cables
Authors: Yang Jiabin , Li Chao , Tian Mengyuan , Liu Shuyu , Shen Boyang , Hao Luning , Ozturk Yavuz , Coombs Tim 
Published: September 2021

AbstractThe conductor on round core (CORC) cable wound with second-generation high-temperature superconducting (HTS) tapes is a promising cable candidate with superiority in current capacity and mechanical strength. The composing superconductors and the former are tightly assembled, resulting in a strong electro-magnetic interaction between them. Correspondingly, the AC loss is influenced by the cable structure. In this paper, a 3D finite-element model of the CORC cable is first built, and it includes the complex geometry, the angular dependence of critical current and the periodic settings. The modelling is verified by the measurements conducted for the transport loss of a two-layer CORC cable. Subsequently, the simulated results show that the primary transport loss shifts from the former to the superconductors as the current increases. Meanwhile, the loss exhibited in the outer layer is larger than that of the inner layer, which is caused by the shielding effect among layers and the former. This also leads to the current inhomogeneity in CORC cables. In contrast with the two-layer case, the simulated single-layer structure indicates stronger frequency dependence because the eddy current loss in the copper former is always dominant without the cancellation of the opposite-wound layers. The core eddy current of the single structure is denser on the outer surface. Finally, the AC transport losses among a straight HTS tape, a two-layer cable and a single-layer cable are compared. The two-layer structure is confirmed to minimise the loss, meaning an even-numbered arrangement makes better use of the cable space and superconducting materials. Having illustrated the electro-magnetic behaviour inside the CORC cable, this work is an essential reference for the structure design of CORC cables.
Effects of long-term deep freezing on human femoral cartilage: differential scanning calorimetric (DSC) analysis and histopathological evaluations
Authors: Szabó Ivett , Patzai Balázs , Lőrinczy Dénes 
Published: September 2021

AbstractResults from our previous study proved that differential scanning calorimetry (DSC) is a reliable method for qualitative evaluation of morphological changes in human cartilage samples caused by cryopreservation and storage time correlates with graft quality [1, 2]. Our current aim was to specify/characterise the effects of deep-freezing on hyaline cartilage in conjunction with length of storage time. Detailed analysis included DSC and histological measurements which showed distinctive differences. Based on our histological examinations, we could not confirm significant association between cartilage destruction and long-time storage, but the DSC results exhibited a definite change in thermal parameters after the 6th week cryopreservation. A modified and more detailed analysis would be useful to determine the effects of deep-freezing.
Financial accounting for deferred taxes: a systematic review of empirical evidence
Authors: Görlitz Anna , Dobler Michael 
Published: September 2021

AbstractDeferred taxes—resulting from differences between financial and tax accounts—have been a long-standing, contentious issue in financial accounting regulation, practice, and research. Debates on concepts and standards have been accompanied by doubts around whether and the extent to which deferred taxes provide relevant information for financial statement users and are employed by firms to manage their earnings. This paper systematically reviews the body of empirical evidence that has emerged over the last three decades on deferred taxes in the fields of value relevance and earnings management. A bibliographic analysis and a narrative synthesis are presented within a thematic categorization framework. Key results indicate that existing research focuses on the US setting. There is substantial evidence for the value relevance of various deferred tax items but limited evidence that firms use deferred taxes to manage their earnings. The findings suggest implications for both future research and the regulatory debate.
Hinweise und Empfehlungen für die Konzeption von Lehrkräftefortbildungen zu digitalen Medien
Authors: Schulze-Vorberg Lukas , Krille Claudia , Fabriz Sabine , Horz Holger 
Published: September 2021

ZusammenfassungUm Unterricht durch digitale Medien lernwirksam gestalten zu können, sollten Lehrkräfte über die notwendigen Kompetenzen für einen didaktisch angemessenen und reflektieren Einsatz von Technologien verfügen. Neben der Verbesserung der technischen Infrastruktur an Schulen ist es daher notwendig, Lehrkräfte bei ihrer Professionalisierung zu unterstützen. Lehrkräfte an deutschen Schulen zeigen allerdings eine eher zurückhaltende Teilnahme an Fortbildungsangeboten zu digitalen Themen, was auf eine fehlende Passung zu den realen Bedarfen hinweisen kann. Der vorliegende Beitrag widmet sich daher Präferenzen von Lehrkräften zu Inhalten und Gestaltungsmerkmalen von Fortbildungen zu digitalen Medien und berichtet dazu Ergebnisse einer Befragung von Gymnasiallehrkräften (N = 238). Um möglichst zielgruppenspezifische Ergebnisse zu erhalten, wurden über eine latente Profilanalyse mit Personenmerkmalen (technologisches und technologisch-pädagogisches Wissen, Selbstwirksamkeit, Mediennutzung) drei Profile identifiziert und im Hinblick auf ihre Präferenzen verglichen. Die Ergebnisse weisen auf eine Vielfalt an thematischen Wünschen sowie auf die Notwendigkeit einer bedarfsgerechten Gestaltung von Fortbildungen hin. Abschließend werden zusammenfassende Empfehlungen zur Gestaltung von Lehrkräftefortbildungen zu digitalen Medien formuliert.
Is the Association Between Education and Sympathovagal Balance Mediated by Chronic Stressors?
Authors: van Nieuwenhuizen Benjamin P. , Sekercan Aydin , Tan Hanno L. , Blom Marieke T. , Lok Anja , van den Born Bert-Jan H. , Kunst Anton E. , van Valkengoed Irene G. M. 
Published: September 2021

Abstract
Background
This study investigated whether raised chronic stress in low education groups contributes to education differences in cardiovascular disease by altering sympathovagal balance.

Methods
This study included cross-sectional data of 10,202 participants from the multi-ethnic, population-based HELIUS-study. Sympathovagal balance was measured by baroreflex sensitivity (BRS), the standard deviation of the inter-beat interval (SDNN) and the root mean square of successive differences between normal heartbeats (RMSSD). The associations between chronic stressors (work, home, psychiatric, financial, negative life events, lack of job control and perceived discrimination) in a variety of domains and BRS, SDNN and RMSSD were assessed using linear regression, adjusted for age, ethnicity, waist-to-hip ratio and pack-years smoked. Mediation analysis was used to assess the contribution of chronic stress to the association between education and sympathovagal balance.

Results
Modest but significant associations were observed between financial stress and BRS and SDNN in women, but not in RMSSD nor for any outcome measure in men. Women with the highest category of financial stress had 0.55% lower BRS (ms/mmHg; β = -0.055; CI = -0.098, -0.011) and 0.61% lower SDNN (ms; β = -0.061; CI = -0.099, -0.024) than those in the lowest category. Financial stress in women contributed 7.1% to the association between education and BRS, and 13.8% to the association between education and SDNN.

Conclusion
No evidence was found for the hypothesized pathway in which sympathovagal balance is altered by chronic stress, except for a small contribution of financial stress in women.
Defect Detection in the Winding Layer of CNG Composite-Wound Cylindersvirtue of minimal mechanism is that it allows
Authors: Lv Hui , Shen Gongtian , Yu Yue , Zhu Lixiong , Zhou Rui 
Published: September 2021

AbstractNatural gas vehicles have been widely used around the world as a mode of green transportation. The defect detection method for a vehicle cylinder, which is the energy storage component of a natural gas vehicle, is essential for ensuring safety. Current vehicle cylinder testing methods are relatively simple and cannot quickly and accurately detect internal defects in the winding layer of the cylinder. In this study, the effect of winding layer defects on the temperature behavior of cylinders during filling was studied using finite element simulation and infrared thermal imaging technology. The results show that a defect in the winding layer acts as a source of thermal resistance that hinders heat transfer. The more serious the defect is, the greater the hindrance of the heat transfer is. According to this principle, an evaluation model based on the R parameter was developed for the temperature changes due to defects, and a method for quantitatively correlating the maximum R value with the defect depth was established, thereby providing a practical approach for the rapid detection and evaluation of defects in cylinder winding layers.
Evaluating genetic and genomic tests for heritable conditions in Australia: lessons learnt from health technology assessments
Authors: Norris Sarah , Belcher Andrea , Howard Kirsten , Ward Robyn L. 
Published: September 2021

AbstractThe Medical Services Advisory Committee (MSAC) is an independent non-statutory committee established by the Australian government to provide recommendations on public reimbursement of technologies and services, other than pharmaceuticals. MSAC has established approaches for undertaking health technology assessment (HTA) of investigative services and codependent technologies. In 2016, MSAC published its clinical utility card (CUC) Proforma, an additional tool to guide assessments of genetic testing for heritable conditions. We undertook a review and narrative synthesis of information extracted from all MSAC assessments of genetic testing for heritable conditions completed since 2016, regardless of the HTA approach taken. Ten assessments met our inclusion criteria, covering a range of testing methods (from gene panels to whole-exome sequencing) and purposes (including molecular diagnosis, genetic risk assessment, identification of congenital anomaly syndromes, and carrier screening). This analysis identified a range of methodological and policy challenges such as how to incorporate patient and societal preferences for the health and non-health outcomes of genomic testing, how best to capture the concept of co-production of utility, and how to engage clinicians as referrers for genomics tests whilst at the same time ensuring equity of access to a geographically dispersed population. A further challenge related to how qualitative assessments of patient and community needs influenced the evidence thresholds against which decisions were made. These concepts should be considered for incorporation within the value assessment frameworks used by HTA agencies around the world.