bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indicators for dental appointment scheduling in primary health care: a national cross-sectional study
Authors: Melo Estêvão Azevedo , Probst Livia Fernandes , Guerra Luciane Miranda , Tagliaferro Elaine Pereira da Silva , De-Carli Alessandro Diogo , Pereira Antonio Carlos 
Published: December 2021

Abstract
Background
Integrated dental services within the Health System, particularly at primary health care, are crucial to reverse the current impact of oral diseases, which are among the most prevalent diseases worldwide. However, the use of dental services is determined by complex phenomena related to the individual, the environment and practices in which care is offered. Therefore, factors associated with dental appointments scheduling can affect positively or negatively the use of dental services. The aim of the present study was to evaluate the indicators for dental appointment scheduling in Primary Health Care (PHC).

Methods
The present is a cross-sectional analytical study that used data from the external assessment of the third cycle of the National Program for Improving Access and Quality in Primary Care (PMAQ-AB), carried out between 2017 and 2018, in Brazil. The final sample consisted of 85,231 patients and 22,475 Oral Health teams (OHTs). The outcome variable was the fact that the user sought for a dental appointment at the Primary Health Care Unit. A multilevel analysis was carried out to verify the association between individual variables (related to users) and contextual variables (related to the OHTs) in relation to the outcome.

Results
Only 58.1% of the users interviewed at these Primary Health Care Units seek the available dental care. The variables with the greatest effect on the outcome were the patient’s age up to 42 years old (OR = 2.03, 95% CI: 1.96–2.10), at individual level, and ‘oral health teams that assisted no more than a single family health team (FHT)’ (OR = 1.29, 95% CI: 1.23–1.36) at contextual level. Other variables were also associated with the outcome, but with a smaller effect size.

Conclusion
In conclusion, users’ age and work process of OHT were indicators for dental appointment scheduling. Our results suggest that when OHT put the National Oral Health Policy guidelines into practice, by assisting only one FHT, the chance for PHC users seeking dental appointments is higher than OHTs that assist more than one FHT. Regarding age, patients aged up to 42 years are more likely to seek an appointment with a dentist.
Evaluation of intraventricular flow by multimodality imaging: a review and meta-analysis
Authors: Mutluer Ferit Onur , van der Velde Nikki , Voorneveld Jason , Bosch Johan G. , Roos-Hesselink Jolien W. , van der Geest Rob J. , Hirsch Alexander , van den Bosch Annemien 
Published: December 2021

Abstract
Background
The aim of this systematic review was to evaluate current inter-modality agreement of noninvasive clinical intraventricular flow (IVF) assessment with 3 emerging imaging modalities: echocardiographic particle image velocimetry (EPIV), vector flow mapping (VFM), and 4-dimensional flow cardiovascular magnetic resonance imaging (4D flow CMR).

Methods
We performed a systematic literature review in the databases EMBASE, Medline OVID and Cochrane Central for identification of studies evaluating left ventricular (LV) flow patterns using one of these flow visualization modalities. Of the 2224 initially retrieved records, 10 EPIV, 23 VFM, and 25 4D flow CMR studies were included in the final analysis.

Results
Vortex parameters were more extensively studied with EPIV, while LV energetics and LV transport mechanics were mainly studied with 4D flow CMR, and LV energy loss and vortex circulation were implemented by VFM studies. Pooled normative values are provided for these parameters. The meta- analysis for the values of two vortex morphology parameters, vortex length and vortex depth, failed to reveal a significant change between heart failure patients and healthy controls.

Conclusion
Agreement between the different modalities studying intraventricular flow is low and different methods of measurement and reporting were used among studies. A multimodality framework with a standardized set of flow parameters is necessary for implementation of noninvasive flow visualization in daily clinical practice. The full potential of noninvasive flow visualization in addition to diagnostics could also include guiding medical or interventional treatment.
Computational method for solving weakly singular Fredholm integral equations of the second kind using an advanced barycentric Lagrange interpolation formula
Authors: Shoukralla E. S. , Saber Nermin , Sayed Ahmed Y. 
Published: December 2021

AbstractIn this study, we applied an advanced barycentric Lagrange interpolation formula to find the interpolate solutions of weakly singular Fredholm integral equations of the second kind. The kernel is interpolated twice concerning both variables and then is transformed into the product of five matrices; two of them are monomial basis matrices. To isolate the singularity of the kernel, we developed two techniques based on a good choice of different two sets of nodes to be distributed over the integration domain. Each set is specific to one of the kernel arguments so that the kernel values never become zero or imaginary. The significant advantage of thetwo presented techniques is the ability to gain access to an algebraic linear system equivalent to the interpolant solution without applying the collocation method. Moreover, the convergence in the mean of the interpolant solution and the maximum error norm estimation are studied. The interpolate solutions of the illustrated four examples are found strongly converging uniformly to the exact solutions.
Initial dispersal behavior and survival of non-native juvenile Burmese pythons (Python bivittatus) in South Florida
Authors: Pittman Shannon E. , Bartoszek Ian A. 
Published: December 2021

Abstract
Background
Dispersal behavior is a critical component of invasive species dynamics, impacting both spatial spread and population density. In South Florida, Burmese pythons (Python bivittatus) are an invasive species that disrupt ecosystems and have the potential to expand their range northward. Control of python populations is limited by a lack of information on movement behavior and vital rates, especially within the younger age classes. We radio-tracked 28 Burmese pythons from hatching until natural mortality for approximately 3 years. Pythons were chosen from 4 clutches deposited by adult females in 4 different habitats: forested wetland, urban interface, upland pine, and agricultural interface.

Results
Known-fate survival estimate was 35.7% (95% CI = 18% - 53%) in the first 6 months, and only 2 snakes survived 3 years post hatching. Snakes moving through ‘natural’ habitats had higher survival than snakes dispersing through ‘modified’ habitats in the first 6- months post-hatching. Predation was the most common source of mortality. Snakes from the agricultural interface utilized canals and displayed the largest net movements.

Conclusions
Our results suggest that pythons may have lower survival if clutches are deposited in or near urbanized areas. Alternatively, juvenile pythons could quickly disperse to new locations by utilizing canals that facilitate linear movement. This study provides critical information about behavioral and life history characteristics of juvenile Burmese pythons that will inform management practices.
Paedomorphosis in the Ezo salamander (Hynobius retardatus) rediscovered after almost 90 years
Authors: Okamiya Hisanori , Sugime Ryohei , Furusawa Chiharu , Inoue Yoshihiro , Kishida Osamu 
Published: December 2021

AbstractAlthough paedomorphosis is widespread across salamander families, only two species have ever been documented to exhibit paedomorphosis in Hynobiidae. One of these two exceptional species is Hynobius retardatus in which paedomorphosis was first reported in 1924, in specimens from Lake Kuttara in Hokkaido. This population became extinct after the last observation in 1932; since then, no paedomorphs of this species have been reported anywhere. Here, we report the rediscovery of paedomorphs of this species. Three paedomorph-like male salamanders were collected from a pond in the south Hokkaido in December 2020 and April 2021; in size, these specimens were similar to metamorphosed adults but they still displayed larval features such as external gills and a well-developed caudal fin. An artificial fertilization experiment demonstrated that they were sexually compatible with metamorphosed females, thus, confirming them to be paedomorphs. Future efforts to find additional paedomorphs in this and other populations are required to assess the prevalence of paedomorphosis in H. retardatus and to improve understanding of the ecology and evolution of paedomorphisis in Urodela.
Cervical musculoskeletal impairments in migraine
Authors: Liang Zhiqi , Thomas Lucy , Jull Gwendolen , Treleaven Julia 
Published: December 2021

Abstract
Background
Neck pain is common and disabling amongst individuals with migraine. Cervical musculoskeletal interventions are often sought but there is currently no evidence to support such interventions for this population. Improved understanding of how cervical musculoskeletal impairments present in migraine can elucidate neck pain mechanisms and guide clinicians and researchers in the management of patients with migraine and neck pain.

Main body
Migraine hypersensitivity is a major consideration when assessing for cervical impairments as it can aggravate migraine and confound findings. Current evidence of cervical impairments in migraine is limited by disregard for the different underlying causes of neck pain and possible influence of hypersensitivity. Findings of cervical musculoskeletal impairments are mixed within and across studies, indicating that different forms of neck pain are present in migraine. Some migraineurs have neck pain that is part of the migraine symptom complex and therefore exhibit little or no cervical musculoskeletal impairment. Others have a cervical source of neck pain and therefore exhibit a pattern of cervical musculoskeletal impairments akin to that of cervical disorders. The presence of cervical musculoskeletal dysfunction may or may not be related to migraine but knowledge of this is currently lacking which impacts decision making on management. Cervical musculoskeletal interventions may be indicated for migraineurs with identified cervical dysfunction but other factors requiring further clarification include determination of i) patient specific outcomes, ii) impact of co-existing migraine referred neck pain, and iii) potential moderating effects of migraine hypersensitivity on treatment efficacy.

Conclusions
Physiotherapists should seek a combination of cervical impairments through skilful assessment to identify if cervical musculoskeletal dysfunction is present or not in individual patients. The relevance of cervical dysfunction to migraine and influence of co-existing migraine referred neck pain need to be established through detailed evaluation of pain behaviours and further research. Future clinical trials should define expected treatment outcomes and select individuals with cervical musculoskeletal dysfunction when investigating the efficacy of cervical musculoskeletal interventions.
Use of the Cascade expandable net to treat cerebral vasospasm – initial clinical experience from a single centre with in vitro benchside tests
Authors: Bhogal P. , Simpanen T. , Wong K. , Bushi D. , Sirakov M. A. , Sirakov S. , Aggour M. , Makalanda L. 
Published: December 2021

Abstract
Background
The use of self-expanding stents to treat post-hemorrhagic cerebral vasospasm was recently described. We sought to determine the clinical efficacy of the Cascade device to treat delayed cerebral vasospasm (DCV). We performed benchside tests to determine the chronic outward force exerted by the Cascade in comparison to the Solitaire.

Methods
The chronic outward force (COF) of the Cascade M agile and Cascade L Agile was tested with equivalent tests of the Solitaire 4x20mm. Further tests to determine the forces generated in pre-formed tubes of 1.5–6 mm were performed using both fully and partially unsheathed Cascades.
A retrospective review to identify all patients with aSAH and DCV treated with a Cascade device between January 2020 and July 2021. We recorded the treatment arterial vessel diameters and hemorrhagic or ischemic complications.

Results
In vitro the Cascade generated greater radial force than the Solitaire. The force generated by the Cascade M Agile at 1.5 mm was approximately 64% higher than the Solitaire 6x40mm and approximately 350% higher than the Solitaire 4x20mm.
4 patients with DCV were identified all of whom were treated with a cascade device. In all cases there was a significant improvement in the diameter of the vasospastic vessels treated with an average diameter increase of approximately 300%. There were no complications from the Cascade. Delayed CT angiography showed persistent dilatation of the segments treated with the Cascade at 24 h.

Conclusion
The Cascade is a safe and effective device when used to treat DCV secondary to aSAH. Larger studies are required to validate our initial results.
Transfer learning for deep neural network-based partial differential equations solving
Authors: Chen Xinhai , Gong Chunye , Wan Qian , Deng Liang , Wan Yunbo , Liu Yang , Chen Bo , Liu Jie 
Published: December 2021

AbstractDeep neural networks (DNNs) have recently shown great potential in solving partial differential equations (PDEs). The success of neural network-based surrogate models is attributed to their ability to learn a rich set of solution-related features. However, learning DNNs usually involves tedious training iterations to converge and requires a very large number of training data, which hinders the application of these models to complex physical contexts. To address this problem, we propose to apply the transfer learning approach to DNN-based PDE solving tasks. In our work, we create pairs of transfer experiments on Helmholtz and Navier-Stokes equations by constructing subtasks with different source terms and Reynolds numbers. We also conduct a series of experiments to investigate the degree of generality of the features between different equations. Our results demonstrate that despite differences in underlying PDE systems, the transfer methodology can lead to a significant improvement in the accuracy of the predicted solutions and achieve a maximum performance boost of 97.3% on widely used surrogate models.
Nutritional assessment and rehabilitation in children with bronchiectasis and childhood interstitial lung diseases: effects on pulmonary functions and clinical severity
Authors: Alsharkawy Asmaa , Fouda Eman , Mujahed Asmaa , Elgendy Yasmin 
Published: December 2021

Abstract
Background
Nutrition is recognized as a modifiable contributor to bronchiectasis and interstitial lung diseases (ChILD) development and progression. Nutritional interventions have great potential in reducing respiratory illness related morbidity and mortality. The study was done to assess nutritional state and body composition of children with bronchiectasis and interstitial lung diseases (ChILD) and to study the effect of short course nutritional intervention program on their growth, clinical symptoms, pulmonary functions and frequency of acute exacerbations and hospitalization. Seventeen patients with bronchiectasis and thirteen patients with interstitial lung diseases and 40 healthy children as controls were enrolled. Nutritional status, chest symptoms, anthropometry, body composition, and spirometric pulmonary function were evaluated. A short course nutritional intervention program was done for patients and then they were re-evaluated.

Results
In total, 56.67% of studied patients were moderately malnourished and 23.33% were severely malnourished. A total of 66.7% of studied patients were underweight and 50% of patients had stunted growth. Anthropometric indices were significantly lower than control groups (P < 0.05). Body composition indices were lower in patients than control but not with a statistical significance. Forced vital capacity was positively correlated to body mass index (P = 0.045). Nutritional rehabilitation significantly improved patient anthropometry (weight, body mass index, height, triceps skin-fold thickness, mid arm circumference), body composition (body fat, fat free mass, and muscle mass), respiratory symptoms, and FEV1. Needs to asthma rescue medications, school absence, acute exacerbation attacks, and hospitalization were reduced.

Conclusion
Patients with bronchiectasis and interstitial lung diseases (ChILD) have malnutrition and body composition changes that improved significantly after short nutritional intervention program with significant improvement in FEV1, frequency of acute exacerbations, and hospitalization.
Comparison of a Nasal Mask and Traditional Nasal Cannula During Intravenous Anesthesia for Gastroscopy Procedures: A Randomized Controlled Trial
Authors: Chen Dong Xu , Yang Hui , Wu Xi Ping , Niu Wang , Ding Lin , Zeng Huo Lin , Li Qian 
Published: December 2021

BACKGROUND:
Hypoxemia can occur during gastroscopy under intravenous anesthesia. The aim of this randomized controlled trial was to evaluate whether oxygenation using a nasal mask can reduce the incidence of hypoxemia during gastroscopy under intravenous anesthesia compared with a traditional nasal cannula.

METHODS:
A total of 574 patients scheduled for gastroscopy under intravenous anesthesia were enrolled and randomly assigned to receive either a nasal mask or a traditional nasal cannula for oxygenation. The primary outcome was the incidence of hypoxemia. The secondary outcomes included the incidence of severe hypoxemia, duration of hypoxemia, minimum oxygen saturation, the proportion of emergency airway management, length of procedure, recovery time, and the satisfaction of the anesthetist and gastroenterologists as well as other adverse events (including cough, hiccups, nausea and vomiting, reflux, aspiration, and laryngospasm).

RESULTS:
A total of 565 patients were included in the analysis: 282 patients in the nasal cannula group and 283 patients in the nasal mask group. The incidence of hypoxemia was lower in the nasal mask group (18.0%) than in the nasal cannula group (27.7%; relative risk [RR] = 0.65; 95% confidence interval [CI], 0.48–0.89; P = .006), and the hypoxemia lasted a median of 18.0 seconds (interquartile range, 10.0–38.8) in the nasal mask group and 32.5 seconds (20.0–53.5) in the nasal cannula group (median difference –14.50; 95% CI, −22.82 to −1.34; P = .047). The proportion of patients requiring emergency airway management was significantly lower in the nasal mask group (8.8%) than in the nasal cannula group (19.1%; RR, 0.46; 95% CI, 0.30–0.73; P < .001). No difference was found in the overall incidence of other adverse events between the 2 groups (nasal mask 20.8%; nasal cannula 17.0%; RR, 1.23; 95% CI, 0.87–1.73; P = .25). Satisfaction was higher with the nasal mask than with the nasal cannula from the perspective of anesthetists (96.1% for nasal mask versus 84.4% for nasal cannula; RR, 1.14; 95% CI, 1.08–1.20; P < .001) and gastroenterologists (95.4% for mask versus 81.9% for cannula; RR, 1.17; 95% CI, 1.10–1.24; P < .001). There were no significant differences in the incidence of severe hypoxemia, minimum oxygen saturation, length of procedure, or recovery time between the 2 groups.

CONCLUSIONS:
Nasal mask oxygenation reduced the incidence of hypoxemia during anesthesia for gastroscopy under intravenous anesthesia.
Interplay among positive and negative symptoms, neurocognition, social cognition, and functional outcome in clinically stable patients with schizophrenia: a network analysis
Authors: Charernboon Thammanard 
Published: December 2021

Background: Schizophrenia has a broad range of interrelated symptoms and impairment in functioning. The objective of the study was to explore the interplay between positive symptoms, negative symptoms, neurocognition, social cognition and functional outcome in patients with schizophrenia using network analysis. Methods: Participants were 64 clinically stable patients with schizophrenia. Psychopathologic, neurocognition, social cognition, and functional outcome were measured using the Scale for the Assessment of Positive Symptoms, Scale for the Assessment of Negative Symptoms, Addenbrooke’s Cognitive Examination III, Faces test, Reading the Mind in the Eyes test, and Personal Social Performance scale. Results: The network analysis suggested that functional outcome was the most central in the network followed by avolition and asociality. Functioning was directly connected to avolition, asociality, blunted affect, neurocognition and emotion recognition. The positive symptoms were the most remote and therefore the least important node. Conclusion: The high centrality of functioning suggests the need for improving of everyday life skills for patients with schizophrenia. Moreover, treatment of specific negative symptoms, neurocognition and emotion recognition could also enhance functional outcome.
Hobotnica: exploring molecular signature quality
Authors: Stupnikov Alexey , Sizykh Alexey , Favorov Alexander , Afsari Bahman , Wheelan Sarah , Marchionni Luigi , Medvedeva Yulia 
Published: December 2021

A Molecular Features Set (MFS), is a result of a vast diversity of bioinformatics pipelines. The lack of a “gold standard” for most experimental data modalities makes it difficult to provide valid estimation for a particular MFS's quality. Yet, this goal can partially be achieved by analyzing inner-sample Distance Matrices (DM) and their power to distinguish between phenotypes. The quality of a DM can be assessed by summarizing its power to quantify the differences of inner-phenotype and outer-phenotype distances. This estimation of the DM quality can be construed as a measure of the MFS's quality. Here we propose Hobotnica, an approach to estimate MFSs quality by their ability to stratify data, and assign them significance scores, that allow for collating various signatures and comparing their quality for contrasting groups.