bluuebunny/crossref_metadata_2025_split huggingface dataset:
Solving climate change requires changing our food systems
Authors: Feigin Svetlana V , Wiebers David O , Blumstein Daniel T , Knight Andrew , Eshel Gidon , Lueddeke George , Kopnina Helen , Feigin Valery L , Morand Serge , Lee Kelley , Brainin Michael , Shackelford Todd K , Alexander Shelley M , Marcum James , Merskin Debra , Skerratt Lee F , Van Kleef Gerben A , Whitfort Amanda , Freeman Carrie P , Winkler Andrea Sylvia 
Published: January 2025

Abstract
Humanity is facing an important existential threat—irreversible climate change caused by human activity. Until recently, most of the proposals to address climate change have downplayed or ignored the adverse impact of food systems, especially intensive animal agriculture. This is in spite of the fact that up to a third of global greenhouse gas production to date can be attributed to animal agriculture. Recent developments at COP28 have signaled that the tide is turning, however, and that food systems are becoming part of global discussions on climate change solutions. The pressing nature of irreversible climate change requires rethinking our food systems. To solve the climate change crisis, we propose transitioning to a predominantly plant-based diet, and phasing out intensive animal agriculture as diets shift, without increasing pastoral farming. We suggest that such transformations in global food systems can be accomplished largely through education and large-scale public information campaigns, removal of subsidies, taxation to account for externalized costs of animal agriculture, improved labelling of products, and various investment/divestment drivers. Better metrics and industry benchmarks involving food and agriculture-specific performance indicators that reflect food system sustainability will be important. Increased global awareness of these issues and a change in mindset (which will drive political will) also are needed. Our current trajectory is untenable, and we must begin to turn the ship now towards sustainable food systems and diets.
Comparing quantitative imaging biomarker alliance volumetric CT classifications with RECIST response categories
Authors: Zhao Binsheng , Obuchowski Nancy , Yang Hao , Chou Yen , Ma Hong , Guo Pingzhen , Tang Ying , Schwartz Lawrence , Sullivan Daniel 
Published: January 2025

Abstract

Purpose
To assess agreement between CT volumetry change classifications derived from Quantitative Imaging Biomarker Alliance Profile cut-points (ie, QIBA CTvol classifications) and the Response Evaluation Criteria in Solid Tumors (RECIST) categories.

Materials and Methods
Target lesions in lung, liver, and lymph nodes were randomly chosen from patients in 10 historical clinical trials for various cancers, ensuring a balanced representation of lesion types, diameter ranges described in the QIBA Profile, and variations in change magnitudes. Three radiologists independently segmented these lesions at baseline and follow-up scans using 2 software tools. Two types of predefined disagreements were assessed: Type I: substantive disagreement, where the disagreement between QIBA CTvol classifications and RECIST categories could not be attributed to the improved sensitivity of volumetry in detecting changes; and Type II: disagreement potentially arising from the improved sensitivity of volumetry in detecting changes. The proportion of lesions with disagreements between QIBA CTvol and RECIST, as well as the type of disagreements, was reported along with 95% CIs, both overall and within subgroups representing various factors.

Results
A total of 2390 measurements from 478 lesions (158 lungs, 170 livers, 150 lymph nodes) in 281 patients were included. QIBA CTvol agreed with RECIST in 66.6% of interpretations. Of the 33.4% of interpretations with discrepancies, substantive disagreement (Type I) occurred in only 1.5% (95% CI: [0.8%, 2.1%]). Factors such as scanner vendor (P = .584), segmentation tool (P = .331), and lesion type (P = .492) were not significant predictors of disagreement. Significantly more disagreements were observed for larger lesions (≥50 mm, as defined in the QIBA Profile).

Conclusion
We conclude that QIBA CTvol classifications agree with RECIST categories.
Addressing the unfettered authority of sport governing bodies through EU competition law: the effect of International Skating Union and European Super League
Authors: Bantekas Ilias , Mercado Jaén Pedro José 
Published: January 2025

Abstract
The unfettered authority of sports governing bodies (SGBs) has given rise to a distinct number of human rights claims, but it has also led to the distortion of the free movement of persons and competition law in the European Union. In the International Skating Union and European Super League Company, the Court of Justice of the European Union (CJEU) emphasized that while SBGs have a right to achieve legitimate sporting aims, such as integrity and sporting fairness, this cannot be done at the expense of competition rules. The CJEU highlighted that SGBs are not allowed to prevent their member associations from organizing and operating competitive leagues and events, nor can they inflict sanctions on them for attempting to do so. These judgments will revolutionize the transnational sports law landscape and reshape SGB institutional rules and their relationships with their members.
Compliance and enforcement in the AIA through AI
Authors: Micklitz Hans-W , Sartor Giovanni 
Published: January 2025

ABSTRACT
The Artificial Intelligence Act (AIA) relies on public authorities to survey and monitor the compliance systems of private companies and establish appropriate discovery mechanisms to render ex-officio enforcement possible. The article analyses the intricacies of compliance and enforcement of the AIA and the interaction between private companies and public authorities, thus preventing the marketing of AI systems that are dangerous to both people and society. The striking complexity of the enforcement structure invites us to consider the use of AI in compliance and enforcement. Such areas to consider are: handling the communication between hundreds of competent national authorities; communication between the European Union (EU) and the private compliance bodies; generating and processing information on the design and use of AI systems, in facilitating regulatory action in the EU as a whole.
Appreciating Appreciation: Residents’ Experience Feeling Valued Differently as Learners, Physicians, and Employees
Authors: Bogerd Rosa , Silkens Milou E.W.M. , Henriques José P.S. , Lombarts Kiki M.J.M.H. 
Published: January 2025

Abstract

Purpose
Cultures of wellness, defined as shared norms, values, attitudes, and behaviors that promote personal and professional growth and well-being, are robust determinants of professional fulfillment and professional performance. A major and largely overlooked aspect of a culture of wellness in medicine is residents’ perceived appreciation or experience of feeling valued. Considering the pressing workforce and retention challenges that residency programs face, this study addressed the following research questions: How does appreciation at work manifest in the eyes of residents and how do residents perceive appreciation in relation to their professional fulfillment and performance?

Method
Guided by an interpretative phenomenological approach, this qualitative study purposively sampled 12 residents from different specialties, training years, regions in the Netherlands, and genders. Residents’ individual experiences with appreciation at work were explored in semistructured interviews conducted between October 2022 and March 2023. Thematic analysis was used for data analysis.

Results
Residents perceived appreciation as “being seen and heard” and further described how appreciation at work manifested using 3 narratives. As learners, residents felt appreciated when their competencies were acknowledged and supervisors created room for individual growth. As physicians or colleagues, residents felt appreciated when they experienced meaningful patient contact, high levels of collegiality, and self-appreciation through successes at work. As employees, residents felt appreciated when their (extra) efforts were noticed, they were properly facilitated in their work and training, and their well-being was prioritized. Residents said that receiving appreciation boosted their mental health, self-confidence, professional commitment, and professional fulfillment, thereby benefiting their performance and the quality of patient care they deliver.

Conclusions
Appreciation at work is important for residents and manifests itself within the narratives of learner, physician or colleague, and employee. Which narrative is foregrounded depends on context, but regardless feeling “seen and heard” at work is crucial for residents’ fulfillment and performance.
Analysis of Mood and Anxiety Disorder Content in Common U.S. Obstetrics and Gynecology Residency Educational Resources
Authors: Lennon Clare , Toscano Marika 
Published: January 2025

Abstract

Purpose
This study investigates mental health–related content to delineate potentially deficient topics for improvement in future obstetrics and gynecology (OBGYN) resident educational curriculum initiatives.

Method
In this quantitative content analysis, educational resources commonly used by OBGYN residents were selected based on a 2020 multi-institutional survey of OBGYN residents and informal group discussion with 32 OBGYN residents from a New York academic institution in April 2020. After independent screening, the authors iteratively developed, tested, and implemented a coding scheme for relevant keywords. The primary outcome was total depression and anxiety content in the educational resource materials. Information about other mental health conditions was additionally collected, and content ratings were assigned. Descriptive statistics were used and interrater reliability calculated. Data were accessed and archived on July 30, 2020, for all future analyses.

Results
From 7 materials reviewed, 36 items were analyzed. The cumulative percentage of resources with mental health–related content was 1.1%. Professional society publications contained the most content at 5.0% (95% CI, 1.4%-12.3%), and a podcast series contained the least at 0.6% (95% CI, 0.02%-3.3%). Depressive (30 [83.3%]), anxiety (12 [33.3%]), and bipolar (9 [25.0%]) disorders were the most common content, whereas posttraumatic stress disorder (5 [13.9%]), postpartum psychosis (4 [11.1%]), obsessive compulsive disorder (3 [8.3%]), and schizophrenia (2 [5.6%]) were the least. The content ratings for schizophrenia, postpartum psychosis, posttraumatic stress disorder, obsessive compulsive disorder, pathophysiology of mental health conditions, lactation safety, and fetal and maternal adverse effects of psychiatric medications and psychiatric disease were low. No educational resource reviewed in this study contained all recommended Council on Resident Education in Obstetrics and Gynecology residency curriculum topics related to mental health.

Conclusions
Mental health disorders are underrepresented in commonly used OBGYN educational resources, reinforcing the need for more comprehensive inclusion of these topics in OBGYN curriculum initiatives.
Current Opinion in Acute Aortic Dissection
Authors: Nappi Francesco 
Published: January 2025

Abstract
In recent years, there have been significant improvements in the management of acute aortic dissection, including screening, diagnosis, and surgical options. However, acute aortic dissection represents a serious cardiovascular disease associated with a high risk of early mortality and significant morbidity in those who emerge from the emergency phase. Considerable progress has been made in the last decade in improving our understanding of the pathophysiology of this disorder. The current classifications of acute aortic dissection have faced challenges. There is a growing scientific consensus in favor of a classification that integrates existing features based on both morphological and functional criteria. The location and size of the initial tear in the innermost layer of the aorta determine the main cause of the aortic dissection. This tear causes the middle layer of the aortic wall to rupture and affects the size of the effected area. It is crucial to determine the necessary course of action for the patient, which may involve emergency surgery, endovascular intervention, or the most appropriate conservative care. The management and monitoring of acute aortic dissection is a constantly evolving field of research. This review provides an overview of preventing, recognizing, and treating life-threatening acute aortic dissections.
When should the tricuspid valve be repaired during mitral valve repair?
Authors: An Kevin R. , Nwajei Ekene , Chu Michael W.A. 
Published: January 2025

Purpose of review
Management of tricuspid regurgitation and annular dilation during mitral valve repair remains controversial. We review the latest evidence on indications to repair the tricuspid valve during mitral valve repair and discuss surgical strategies and complications.

Recent findings
Concomitant tricuspid valve repair of moderate tricuspid regurgitation is effective in reducing tricuspid regurgitation progression at 2 years, but has not shown benefit to late survival, quality of life, or functional benefit, and is associated with increased permanent pacemaker implantation (PPM) rates, which is associated with reduced late survival. Progression of less than moderate tricuspid regurgitation with annular dilation alone is uncommon, obviating the need for concomitant repair.

Summary
Repairing concomitant moderate tricuspid regurgitation at the time of mitral repair reduces tricuspid regurgitation progression at 2 years, at the cost of a higher PPM implantation rate. However, repairing less than moderate tricuspid regurgitation for annular dilation alone has not been shown to reduce tricuspid regurgitation progression, bringing current guideline recommendations surrounding repair for annular dilation into question. Longer-term follow-up data, at 5 years, will shed further light on this topic.
OCT Angiography characteristics of Bilateral Mactel type 1: revealing the Aneurysmo occlusive variety.
Authors: Pradhan Amrita , Sen Ahana , Chowdhury Ruchira , Sharma Survee , Majumdar Bristi , Chattree Surabhi , Das Debmalya , Nigam Eesh , Saurabh Kumar , Roy Rupak 
Published: January 2025

Purpose:
To report OCTA (Optical coherence tomography angiography) characteristics of bilateral MacTel type 1 with capillary obliteration.

Method:
Colour fundus photo (CFP), OCT angiography (OCTA), Fundus fluorescein angiography (FFA), Fundus autofluorescence (FAF)

Result:
We describe three cases of bilateral MacTel Type 1 with a special emphasis on OCTA characteristics.

Conclusion:
OCTA is a non-invasive method to detect capillary telangiectasia and abnormal vascular tortuosity in the superficial capillary plexus and deep capillary plexus. OCT angiography demonstrates that bilateral mactel type 1 may have both aneurysmal and occlusive components.
Developing a New Paradigm for Healthcare Delivery: Lessons Learned from Same-Day Access
Authors: Chen Allen M. 
Published: January 2025

Goal:
Excessively lengthy wait times for appointments with clinicians are a major source of frustration for patients, and difficulties with access represent a public health problem facing populations across all societies. As delays in care have been associated with inferior outcomes, same-day appointments have been proposed as a patient-centric means of improving healthcare delivery. However, this paradigm represents a radical shift from conventional scheduling tactics, and skepticism has long existed regarding its feasibility and real-world applicability to clinical practice. Given the limited data available about same-day access and the lack of guidance on this strategy, the need to evaluate experiences and engage in introspective reflection (i.e., examine thoughts, emotions, judgments, and perceptions) for quality improvement are paramount. Thus, the purpose of this study was to review a single-institutional practice with same-day access, focusing on lessons learned over a two-year period.

Methods:
From March 2021 to March 2023, a total of 4,301 consecutive patients with newly diagnosed cancer were offered same-day appointments as part of a prospective pilot initiative conducted in the outpatient setting at a tertiary-based academic medical center. Systematic analysis demonstrated the positive impact of this initiative on access-related benchmarks. A retrospective review was conducted to identify core themes pertaining to the feasibility of the initiative with respect to its design and implementation. An interpretive synthesis was then presented in descriptive fashion.

Principal Findings:
Of the 3,414 patients scheduled, 477 (14%) opted for same-day appointments. While same-day appointments significantly reduced the time to consultation and treatment for patients with newly diagnosed cancer, the initiative presented new challenges—both expected and unexpected—that could have hindered its development, acceptance, and adoption. These challenges related to scheduling capacity, logistical coordination, workflow efficiency, resource allocation, and cultural change. A consistent, proactive management approach, coupled with an unwavering commitment to communication, was required to overcome these operational barriers.

Practical Applications:
Same-day appointments in the ambulatory setting has the potential to improve health outcomes and care quality, while fundamentally changing the way healthcare is delivered for the betterment of patients. However, thoughtful preparation and team-based planning are imperative to establish a methodical approach that will optimize the likelihood of success. Given the potentially disruptive nature of this paradigm, the need for steady leadership, accompanied by the consistent promotion of standardized guidelines, is critical to ensure engagement among all stakeholders. Lastly, the importance of promoting positive cultural change and creating an environment of shared purpose, trust, and transparency cannot be overemphasized.
Corporate Motivation and Performance to Participate in the Government-Led Health Productivity and Management Initiatives in Japan
Authors: Sakai Kosuke , Nakazawa Shoko , Furuya Yuko , Fukai Kota , Tatemichi Masayuki 
Published: January 2025

Objective
In this study, we aimed to structure motivation for workplace health promotion (WHP) and explore the relationship between motivation and WHP performance.

Methods
We qualitatively categorized the WHP motivations written on the Health Productivity and Management (HPM) survey sheet in Japan. We then quantitatively analyzed the relationship between the categories and their HPM rankings using multiple logistic regression.

Results
Responses from 2003 companies were analyzed. The WHP motivations were summarized into 12 categories. Higher-ranked companies more frequently mentioned corporate impressions, workplace environments, employee productivity, employee autonomy, and system management and less often mentioned recruitment and retention.

Conclusions
For more effective WHPs, companies need to support their current workforce, set specific goals, and allocate resources in the appropriate direction, such as increasing work engagement.
Parenteral lipid emulsions: the state of the art
Authors: Da Prat Valentina , Caccialanza Riccardo , Cotogni Paolo 
Published: January 2025

Purpose of review
Several types of injectable lipid emulsions (ILEs) have become available for parenteral nutrition. The purpose of this review is to highlight the most recent and interesting articles in the field of ILEs.

Recent findings
Recent literature has compared ILEs in various clinical scenarios (e.g. abdominal surgery, chronic intestinal failure, critical illness, and preterm birth). Favorable clinical effects of ILEs containing fish oil have been observed in studies on surgical patients with Crohn's disease, critically ill patients, and patients with intestinal failure-associated liver dysfunction, whereas other trials have shown no clear benefit. Ongoing research is focused on finding novel strategies to reduce liver toxicity of ILEs, including the use of ‘artificial intelligence’ tools and liver organoids. Promising new applications for ILEs are emerging, including the prevention of neonatal hypoxic brain injury.

Summary
Although ILEs with the goal of reducing the levels of pro-inflammatory omega-6 fatty acids appear to confer some advantage in some settings (e.g. surgery), conclusive data on the superiority of one ILE over another are lacking. In particular, research is needed to compare different types of mixed-oil ILEs with each other and with pure fish oil ILEs.
Short-chain fatty acids in clinical practice: where are we?
Authors: Martindale Robert G. , Mundi Manpreet S. , Hurt Ryan T. , McClave Stephen A. 
Published: January 2025

Purpose of review
Once considered to have only local influences on the gut mucosa, short-chain fatty acids (SCFAs) now appear to have a much wider anti-inflammatory, immune-modulating, systemic effect. This article reviews recent evidence to suggest a much wider clinical application of this valued dietary substrate.

Recent findings
SCFAs act systemically through stimulation of G protein receptors (GPRs) and inhibition of histone deacetylases (HDACs). SCFAs cause appetite suppression, reduce systemic inflammation, improve insulin sensitivity, increase energy expenditure, promote mitochondrial function, stimulate satiety, reduce blood pressure, and improve cognitive function from various neurologic maladies.

Summary
Dietary strategies should be implemented to provide this beneficial substrate across a wide spectrum of disease conditions. Use of prebiotic fiber or liquid supplements containing high SCFA-producing organisms should be considered as therapeutic targets for multiple metabolic, immunologic, and neurodegenerative diseases.
The impact of n-3 polyunsaturated fatty acids in patients with cancer: emerging themes
Authors: van der Meij Barbara , Parsons Sarah , Mazurak Vera 
Published: January 2025

Purpose of review
This review summarizes recent literature falling broadly under the topic of n-3 polyunsaturated fatty acids (PUFAs) in the oncology setting, highlighting emerging themes and emphasizing novel explorations.

Recent findings
Meta-analyses continue to confirm safety and efficacy of n-3 PUFA supplementation on reducing inflammation and improving survival in people with cancer. Common themes in recent studies emphasize improving tumor-directed efficacy and reducing toxicities of common cancer therapies. New areas of interest include the impact of n-3 PUFA when combined with immunotherapies and applications in pediatric acute lymphoid leukemia. Novel assessments include specialized pro-resolving lipid mediators, the intestinal microbiome and psychological well being. A variety of clinically relevant outcomes including nutritional status, toxicities and survival are being explored in ongoing clinical studies.

Summary
Evidence confirms the safety of n-3 PUFA for patients with cancers, as well as benefits in some, but not all areas of exploration. Larger, well designed trials with biological assessment of compliance compared to the prescribed n-3 PUFA dose would strengthen the evidence needed to integrate n-3 PUFA recommendations into clinical practice for patients with cancer.