bluuebunny/crossref_metadata_2025_split huggingface dataset:
"Yo soy la rumba", de Ángel Gustavo Infante. Construcción y deconstrucción de una identidad posmoderna
Authors: Alarcón Bermejo Javier Ignacio 
Published: March 2021

En el título de la única novela de Ángel Gustavo Infante, Yo soy la rumba (1992), se enuncia una identidad. Esta se forma desde la música y a través del texto, produciendo un “yo” intratextual que se estructura a partir de su relación con la música, la radio, el periódico y otros textos literarios. La novela narra la vida de un compositor de salsa, su infancia en el “cerro” y su madurez en la movida underground de salsa caraqueña. El resultado es, siguiendo el análisis que realiza Dällenbach en El relato especular, una mise en abyme que reproduce dentro del texto tanto al creador como al proceso creativo: la obra es un relato especular que refleja en sus páginas la producción del texto artístico. Este mecanismo está sostenido por una intertextualidad metaléptica: el texto se inserta, de manera consciente, dentro una tradición que incluye otra obra del mismo autor, Cerrícolas (1987), y construye una identidad diferente y cercana a la de Infante. La especularidad aparece, entonces, a través de un collage de referencias intermediales: la imitación de libretos de radios, jingles, fragmentos de canciones, recortes publicitarios del periódico. Sobre todo, la prosa de Infante deviene en el ritmo de la música que busca emular: la salsa, el bolero, etc. Tomando esto en cuenta, podemos afirmar que la novela construye una identidad ficticia que sirve para reflexionar en torno a lo que llamaremos la identidad posmoderna y que refleja, dentro del texto, la función autorial del discurso.
Al borde del desastre. "Manigua" de Carlos Río
Authors: Catalin Mariana 
Published: March 2021

El presente trabajo se divide en dos momentos. En la primera sección, se interrogan diferentes marcos teóricos para elaborar una diferencia entre supervivencia y sobrevivencia, en función de las temporalidades y los modos del final que las habilitan y las lógicas y valoraciones con que se las asocia, intentando destacar las tensiones que las vinculan. En la segunda sección se aborda la novela Manigua de Carlos Ríos para observar cómo el relato a la vez que vuelve necesaria esa distinción para poder dar cuenta de la complejidad de las temporalidades que la componen, la pone en jaque a través de una indecibilidad determinante entre ambas a partir de los modos en que obliga a imaginar el final.
Blanca Varela y el gran aire de las palabras
Authors: Ferrero Cándenas Inés 
Published: March 2021

En este artículo señalo y reflexiono en torno a la idea de un pacto poético en la obra de la poeta peruana Blanca Varela (1926-2009). Este pacto lo llamo “el gran aire de las palabras”, en referencia a uno de sus versos, e implica una actitud poética, un devenir en la palabra, un constante movimiento de la conciencia vareliana que, en mi opinión, constituye la piedra angular de su poesía. Mi trabajo articula el modo en el que este pacto comienza en su primer poemario, Este puerto existe (1959) y termina de cristalizarse en Ejercicios Materiales (1993) y en El libro de Barro (1994). Para ello, tomo como referencia su poesía reunida en la antología Canto Villano, escogiendo sus versos a modo de antología personal y sin orden cronológico.
Antibacterial activity of selected varieties of Malaysian honey against Escherichia coli: A comparative study
Authors: Alkafaween Mohammad A. , Al-Jamal Hamid A. Nagi , Mohmd Hilmi Abu Bakar 
Published: March 2021

Background: The purpose of this study was to investigate antibacterial activity of three varieties of Malaysian honey; Tualang honey (TH), Gelam honey (GH), and Acacia honey (AH) against Escherichia coli.
Methods: The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the honey samples against E. coli were determined by the broth microdilution assay in the presence and absence of catalase enzyme. The mode of inhibition of honey samples against E. coli was investigated by the effect of time on viability. Impacts of the honeys on the expression profiles of the selected genes of E. coli were examined using RT-qPCR analysis.
Results: The results showed that TH and GH honey possessed lowest MIC and MBC values against E. coli with 20% and 25% (w/v) respectively. Highest MIC and MBC values were observed by AH honey against E. coli with 25% (w/v) and 50% (w/v) values respectively. Among the tested honeys, TH and GH exhibited the highest total antibacterial activity and the highest levels of peroxide-dependent activity. Time–kill curve demonstrated a bactericidal rather than a bacteriostatic effect; with a 2-log reduction estimated within 540 min. Viable cells were not recovered after 9 hours exposure to MIC of all honey-treated. The RT-qPCR analysis showed that all honey-treated cells share a similar overall pattern of gene expression, with a trend toward reduced expression of the virulence genes of interest.
Conclusion: This study demonstrates that Malaysian honey have the potential to be effective inhibitor and virulence modulator of E. coli via multiple molecular targets.
Bosnian Chardaklia House: The Dzider Familyʹs House in The Crnoc Village near Kakanj
Authors: Hadrovic Ahmet 
Published: March 2021

The Dzider familyʹs house in the Crnoc village near Kakanj is located on the flat terrain of a steep slope with southwestern insolation (Figure 1). It is one of a large number of relatively preserved bosnian chardaklia houses in the area of Kakanj, in the territory of Bosnia and Herzegovina where the most developed types of Bosnian chardaklia house were built (Figure 2).
The house was built during the reign of the Ottoman Empire (before the 19th century), but to date it has undergone a number of reconstructions and renovations[1]. It belongs to the type of two-tracts bosnian chardaklija house. One of the most valuable features of this house (except for its age) is the fact that it was erected on a living water source, which is still in the basement of the house today.
Ethnicity and Neonatal Lupus Erythematosus Manifestations Risk in a Large Multiethnic Cohort
Authors: Diaz Talia , Dominguez Daniela , Jaeggi Edgar , Knight Andrea M. , Laskin Carl A. , Ng Lawrence , Silverio Franklin , Silverman Earl D. , Hiraki Linda T. 
Published: April 2021

ObjectiveTo evaluate the association between ethnicity and neonatal lupus erythematosus (NLE), as well as specific NLE manifestations in a large multiethnic population.MethodsWe conducted a cohort study of the children (≤ 1 yr of age) seen in the NLE clinic at The Hospital for Sick Children (SickKids), between January 2011 and April 2019. The cohort was divided into European, non-European, and mixed European–non-European groups according to parent-reported child’s ethnicity (Canada Census categories). Outcomes were NLE and specific NLE manifestations (cardiac, cutaneous, cytopenias, transaminitis, and macrocephaly). The frequency of NLE and specific manifestations were compared between ethnic groups (Fisher exact test). We tested the association between ethnicity and (1) NLE risk, and (2) specific NLE manifestations with logistic regression models, including covariates for child’s sex, maternal rheumatic disease status during pregnancy, and maternal use of antimalarials during pregnancy (multiple comparisons threshold P < 0.008).ResultsWe included 324 children born to 270 anti-Ro antibody–positive mothers. Median age at first visit was 1.8 (IQR 1.4–2.3) months, and median follow-up time was 12 (IQR 2–24) months. The majority was non-European (48%), with 34% European, and 18% mixed European–non-European. There was no significant association between non-European ethnicity (OR 1.18, 95% CI 0.71–1.94, P = 0.51), mixed European–non-European ethnicity (OR 1.13, 95% CI 0.59–2.16, P = 0.70), and NLE risk compared with European ethnicity. We also did not find an association between ethnicity and specific NLE manifestations in univariate or multivariable-adjusted models.ConclusionIn a large multiethnic cohort, there was no association between a child’s ethnicity and NLE risk or specific NLE manifestations.
Real-world data of second-line immunotherapy in metastatic clear cell renal cell carcinoma
Authors: Abbas Waseem , Aggarwal Anjali , Pankaj Promila , Jain Rachna 
Published: March 2021

Background:
Targeted therapies have prolonged the survival of patients with metastatic renal cell carcinomas (RCC). However, the majority of patients with metastatic RCC develop treatment resistance and disease progression. The programmed cell death protein 1 inhibitors offer a new ray of hope for such patients.

Objectives:
The primary objective of this study was to evaluate the overall survival (OS) of patients with relapsed metastatic RCC treated with immunotherapy in the second-line setting. The secondary objectives were to assess the safety profile and objective response rate (ORR) for nivolumab.

Materials and Methods:
This retrospective study was conducted in the Department of Medical Oncology at the Max Institute of Cancer Care, a tertiary care center in Delhi, India. Patients with histologically proven stage IV RCC who had progressed on first-line tyrosine kinase inhibitors (TKIs) and treated with at least four cycles of nivolumab at our center between December 2015 and January 2019 were enrolled in the study. The OS, progression-free survival (PFS), immune-mediated adverse events (irAEs), and ORR were determined.

Results:
Out of 50 patients with metastatic RCC who progressed on first-line TKIs, 19 received immunotherapy with nivolumab. The median age of the patients was 62 years (range, 31–71 years); the male-to-female ratio was 2:1. The median follow-up time and duration of treatment were 11 months (range, 2–23) and 4.5 months (95% confidence interval [CI], 3.52–5.96), respectively, and 8 (42.1%) patients were alive at the time of analysis. The median OS was 13 months (95% CI, 10.4–15.5) from the start of nivolumab therapy, and the median PFS was 8 months (95% CI, not evaluable). The best response was progressive disease in 47.3%; the ORR was 26.3%. Grade 1/2 and grade 3/4 adverse events were observed in 68.4% and 10.5% of the patients, respectively. Adverse events of any grade were reported in 13 (68.6%) patients. Fatigue and hypothyroidism were the most frequently observed irAEs associated with nivolumab and occurred in 4 (21%) and 11 (57.8%) patients, respectively. Four (15.7%) patients developed grade 1 pruritus. No fatal toxicities were recorded.

Conclusion:
Nivolumab is efficacious and safe as a second-line treatment option for metastatic RCC in Indian patients.
Neuropsychological functioning in long-term survivors of pediatric acute lymphoblastic leukemia
Authors: Abraham Jisha , Veeraiah Surendran , Radhakrishnan Venkatraman 
Published: March 2021

Background:
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Given the improvement in the survival of patients with ALL over the last few decades, the adverse effects of treatment and disease on survivors have become a major concern. Neuropsychological functioning has been reported to be affected in long-term survivors of ALL and can impact their quality of life.

Objective:
The objective of the study was to assess the neuropsychological functioning of long-term survivors of pediatric ALL.

Materials and Methods:
This prospective cross-sectional study was conducted at the Cancer Institute, Chennai, India, between March and August 2014. Pediatric patients with ALL who had survived at least 2 years after treatment and were in remission were included in the study. Various neuropsychological domains such as sustained attention, focused attention, verbal working memory, immediate memory, verbal learning, immediate recall, delayed recall, visuoconstructive ability, and visuomotor speed were assessed using age-appropriate tests. Data were analyzed using descriptive statistics and nonparametric tests such as the Mann–Whitney U and Kruskal–Wallis H-tests. P < 0.05 was considered statistically significant.

Results:
Of the 51 participants, there were 30 male and 21 female survivors. Their median ages at diagnosis and assessment were 8.6 years and 18.3 years, respectively. Adult survivors (n = 31) were found to have deficits in immediate memory, verbal learning, immediate recall, visuoconstructive ability, and visuomotor speed. Adolescent survivors (n = 20) were found to have deficits in immediate memory and verbal working memory. Survivors aged 8 years or more at diagnosis had better focused attention and verbal working memory, while those diagnosed at age <8 years had better visuoconstructive ability. Those with longer survival had better verbal working memory.

Conclusions:
Long-term survivors of pediatric ALL experience deficits in various neuropsychological functions. Adult survivors have deficits in immediate memory, visuoconstructive ability, verbal learning, immediate recall, and visuomotor speed, whereas adolescent survivors have deficits in immediate memory and verbal working memory.
Impact of COVID-19 lockdown on patients with cancer in North Bihar, India
Authors: Singh Ravikant , Rai Chanda , Ishan Rohit 
Published: March 2021

Background:
In India, the coronavirus disease-2019 (COVID-19) outbreak led to an extensive lockdown, leaving the other time-sensitive medical conditions, such as cancer unaddressed. Patients with cancer are extremely vulnerable to infections owing to their already immunocompromised status and the need for prolonged treatment.

Objectives:
We aimed to study the impact of the COVID-19 lockdown on the utilization of health-care services by patients with cancer in the Muzaffarpur district of North Bihar, India.

Materials and Methods:
This descriptive, cross-sectional study was conducted at a preventive oncology clinic in the Muzaffarpur district of North Bihar in India. All consecutive patients registered in the population-based cancer registry of Muzaffarpur were telephonically contacted between April 15, 2020, and May 7, 2020, during the first phase of the nationwide lockdown. The patients were asked questions related to their disease, treatment status, and impact of the lockdown on their treatment. Detailed responses were recorded and analyzed.

Results:
The study comprised 210 patients of which majority were women (62.9%) and aged more than 40 years (77.1%). A total of 162 (77%) patients were found to be affected by the lockdown, of which 137 (65.4%) missed their scheduled visits, 1 (0.5%) missed surgery, 1 (0.5%) missed chemotherapy, and 24 (11.4%) could not get the prescribed drugs. Most patients who missed their scheduled appointments were aged more than 60 years, women, inhabitants of rural areas, with multiple comorbidities, or belonged to the lower middle-income economic strata. About 70% of the patients faced transportation issues, and 55% experienced financial problems during the lockdown.

Conclusion:
The lockdown led to difficulties in accessing cancer care in almost 80% of the patients with cancer. This suggests the need for strategic planning of health-care services for patients with cancer during the current pandemic, by means of telemedicine consultation, home-based palliative care services, and ensuring the availibility of essential cancer drugs.
Cancer-related fatigue and its impact on quality of life in patients with central nervous system tumors
Authors: Singh Gunjesh Kumar , Varghese Litty , Menon Nandini , Dale Ochin , Patil Vijay M. 
Published: March 2021

Background:
Cancer-related fatigue (CRF) has a high prevalence in individuals with cancer, especially in those with central nervous system (CNS) tumors, and impacts the quality of life (QOL). However, there are limited data on CRF in Indian patients with CNS tumors.

Objective:
We aimed to estimate the CRF scores in patients with CNS tumors.

Materials and Methods:
This cross-sectional study was conducted in the Department of Medical Oncology of the Tata Memorial Hospital in Mumbai, India, between May 2019 and August 2019. Patients with CNS tumors aged ≥18 years, who presented to the Neuro-Oncology Disease Management Group, were enrolled in the study. The Functional Assessment of Chronic Illness Therapy Fatigue Scale was used to collect data related to well-being and fatigue. Data were captured in a single visit. Descriptive statistics and multiple regression analyses were performed to identify the factors associated with a high fatigue score.

Results:
There were 100 patients in our cohort with a median age of 40 (range, 18–64) years. The median fatigue score was 36. The median physical well-being, social well-being, emotional well-being, functional well-being, and Functional Assessment of Cancer Therapy-General (FACT-G) scores were 19, 19.9, 18, 17, and 72, respectively. There was a significant correlation between the fatigue score and the various subscales of FACT-G (P < 0.0001). The associated risk factors for CRF were age (P = 0.021), poor Eastern Cooperative Oncology Group-Performance Status (ECOG PS) (2–3) (P < 0.0001), general category based on the payment ability of the patient (P = 0.004), ongoing treatment status (P = 0.0003), and the presence of recurrent disease (P = 0.001).

Conclusion:
CRF is common in patients with CNS tumors and impacts all aspect of the QOL. It is affected by age, ECOG PS, payment ability, treatment status, and disease recurrence status.
A Review: Genetics Algorithms in Bioinformatics Tools
Authors: Najeb Mohammed Bafreen 
Published: March 2021

Bioinformaticians study biological questions by analyzing molecular data with various programs and tools. Today, bioinformatics is used in large number of fields such as microbial genome applications, biotechnology, waste cleanup, Gene therapy, fingerprint and eye detection. The field of bioinformatics, is one of the most prominent areas that our need is increasing, and the demand for it is increasing day by day. Where dealing with this vital and biological information using advanced computer technologies to generate useful information and new discoveries. For this reason, vital bioinformatics is one of the domains that combines both interested and programming at the same time. It provides you with resources for self-learning, the most important information in the field of vital information, and asked questions of those wishing to learn this field. The term bioinformatics was first used in 1968 by Margret Dayhoff, which is a pioneer in this field, but its definition appeared for the first time in 1978. This science arose and developed in conjunction with the emergence and development of computers. It is also referred to as "computational biology."
Investigation of the Organizational Commitment and Psychological Well-being Levels of Academicians
Authors: Yalçın Sinan , Akan Durdağı , Yıldırım İsa 
Published: March 2021

In this research, which aims to investigate the organizational commitment and psychological well-being of academicians, the quantitative research method was employed. The research was designed in the relational screening model. The sample of the research consisted of 132 academicians at the Erzincan Binali Yıldırım University located in the Eastern Anatolia Region of Turkey in the 2018-2019 academic year. The research data were collected with the organizational commitment and psychological well-being scales. The data of the research were analyzed with the SPSS package program. The frequency, t-test, one-way (ANOVA) analysis, correlation and regression analysis were applied in the analysis of the data. According to the results reached in the study, the psychological well-being levels of the academicians were found to be high, their organizational commitment levels were at a moderate level. As it was analyzed in terms of the sub-dimensions of the organizational commitment, the emotional commitment of the academicians was found to be high, normative and the attendance commitment was at a moderate level. According to another result reached in the study, a positive significant relationship was encountered between the psychological well-being levels of the academicians and their organizational commitment levels. According to another result, the psychological well-being levels of the academicians were a significant predictor on the emotional and normative commitment, which are sub-dimensions of the organizational commitment, but was not a significant predictor of the attendance commitment.
Determination of Deposit Insurance Premium (LPS): Mertonâ€™s Option Theory with Co-Insurance Consideration
Authors: Pandiangan Naomi 
Published: March 2021

Indonesia is a developing country that implements a deposit insurance system. Deposit Insurance Agency or LPS is an Indonesian deposit insurance established in 2004, which is Indonesian still unfamiliar with LPS, both among researchers, and the general public. Almost all deposit insurance in every country including Indonesia has the same problem, the problem is how to calculate premiums and how to avoid moral hazard by banks, therefore in this study will discuss how to determine premiums from the development of Black-Scholes option theory (1973) conducted by Merton (1977). To prevent banks from engaging in moral hazard, co-insurance is considered in this study, which is banks take the risk to anticipate 'excessive risk-taking' behavior. that occurs if the value of the asset isÂ smaller than value of the deposit after joining the insurance program. So it is expected to encourage banks to beware.
IMPLEMENTASI PENGGUNAAN BAHASA INGGRIS PADA PEMBELAJARAN PAI DINIYAH ULYA KELAS 4 DENGAN METODE COLLABORATIVE LEARNING DI PONDOK PESANTREN MIFTAHUL HUDA AL-AZHAR CITANGKOLO
Authors: Kusmayadi Yudi 
Published: March 2021

This research has a background that the era of globalizationraises the community's need for international schools that have theconcepts and systems needed for international standard schools thatactually implement the international system. Not only limited to thecover or international appearance, but the content and purposeaccording to the label displayed. So that it can answer people's anxiety.This study aims to describe the implementation of the use of English inPAI learning in diniyah ulya grade 4 by using the CollaborativeLearning method at Miftahul Huda Al-Azhar Islamic Boarding Schoolin Citangkolo Banjar, Including the preparation, implementation, and evaluation ofPAI learning, advantages and disadvantages, obstacles and solutionsfor Implementation of English using English in PAI learning in diniyahulya grade 4 by using Collaborative Learning method in Islamicboarding school Miftahul Huda al Azhar Citangkolo Banjar City Theresults of this study are (1) Implementation of the use of English in PAIlearning in grade 4th grade ulya Madrasah Ali Miftahul Huda Al AzharCitangkolo Banjar as a whole is in accordance with the guidelines oflearning programs with the use of foreign languages. language. (2) thebenefits of implementing the use of English motivate teachers andstudents to master English better, foster greater self-confidence inteachers and students, students avoid speaking improperly / disrespectfully, increasing students' abilities or skills (abilities) inEnglish, add teacher insight. Deficiencies in the form of timeeffectiveness (3) constraints in the form of teacher recruitment,standardization of the English language ability of PAI teachers,building madrasa culture, mastering English that is owned by teachersand students. Solutions in the form of conducting English learning forteachers and students, supplementary learning for students in theafternoon, conducting training for teachers, delegating PAI teachers tobuild madrasa culture, making corrections to lesson plans, andteaching practices (Micro Teaching), controlling language