bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neuromyelitis optica spectrum disorders with non opticospinal manifestations as initial symptoms: a long-term observational study
Authors: Li Rui , Lu Danli , Li Hao , Wang Yuge , Shu Yaqing , Chang Yanyu , Sun Xiaobo , Lu Zhengqi , Qiu Wei , Yang Zhi 
Published: January 2021

AbstractBackgroundEarly stage neuromyelitis optica spectrum disorders (NMOSD) with non-opticospinal manifestations as initial symptoms are easily misdiagnosed; however, data on the full symptom profile are limited. Moreover, the clinical characteristics and long-term outcomes of these patients remain unknown. We sought to analyze the clinical characteristics, imaging features, and long-term outcomes of NMOSD with non-opticospinal manifestations as initial symptoms.MethodsWe retrospectively included relevant patients from our center. Clinical, demographic, magnetic resonance imaging, treatment, and outcome data were compared according to the non-opticospinal vs. opticospinal initial symptoms.ResultsWe identified 43 (9.13 %) patients with non-opticospinal initial symptoms among 471 patients with NMOSD. Of these, 88.37 % developed optic neuritis/myelitis during an average follow-up period of 6.33 years. All the non-opticospinal symptoms were brain/brainstem symptoms. Most of the symptoms and associated brain lesions were reversible. These patients had a younger onset age (P < 0.001), lower serum aquaporin-4 (AQP4) antibody titers (P = 0.030), and a lower Expanded Disability Status Scale (EDSS) score at onset (P < 0.001) and follow-up (P = 0.041) than NMOSD patients with opticospinal initial symptoms. In addition, EDSS scores reached 3.0 (indicating moderate disability) later than in patients with opticospinal initial symptoms (P = 0.028).ConclusionsPatients with NMOSD with non-opticospinal initial symptoms have a younger onset age, lower serum AQP4 antibody titers, and better clinical outcomes.
The role of Chito-oligosaccharide in regulating ovarian germ stem cells function and restoring ovarian function in chemotherapy mice
Authors: Huang Yaoqi , Ye Haifeng , Zhu Feiyin , Hu Chuan , Zheng Yuehui 
Published: January 2021

AbstractIn recent years, the discovery of ovarian germ stem cells (OGSCs) has provided a new research direction for the treatment of female infertility. The ovarian microenvironment affects the proliferation and differentiation of OGSCs, and immune cells and related cytokines are important components of the microenvironment. However, whether improving the ovarian microenvironment can regulate the proliferation of OGSCs and remodel ovarian function has not been reported. In this study, we chelated chito-oligosaccharide (COS) with fluorescein isothiocyanate (FITC) to track the distribution of COS in the body. COS was given to mice through the best route of administration, and the changes in ovarian and immune function were detected using assays of organ index, follicle counting, serum estrogen (E2) and anti-Mullerian hormone (AMH) levels, and the expression of IL-2 and TNF-α in the ovaries. We found that COS significantly increased the organ index of the ovary and immune organs, reduced the rate of follicular atresia, increased the levels of E2and AMH hormones, and increased the protein expression of IL-2 and TNF-α in the ovary. Then, COS and OGSCs were co-cultured to observe the combination of COS and OGSCs, and measure the survival rate of OGSCs. With increasing time, the fluorescence intensity of cells gradually increased, and the cytokines IL-2 and TNF-α significantly promoted the proliferation of OGSCs. In conclusion, COS could significantly improve the ovarian and immune function of chemotherapy model mice, and improve the survival rate of OGSCs, which provided a preliminary blueprint for further exploring the mechanism of COS in protecting ovarian function.
The association of priori and posteriori dietary patterns with the risk of incident hypertension: Tehran Lipid and Glucose Study
Authors: Ramezankhani Azra , Hosseini-Esfahani Firoozeh , Mirmiran Parvin , Azizi Fereidoun , Hadaegh Farzad 
Published: January 2021

Abstract
Background
The aim of this study was to investigate the association of dietary patterns with incident hypertension.

Materials/methods
This prospective study was conducted on 4793 individuals of Tehran lipid and glucose study participants, aged ≥ 18 years who were followed for a median of 6.3 years from 2008–2011 to 2016–2018. A valid and reliable semi-quantitative food frequency questionnaire was used to assess usual dietary intakes. Anthropometrics and blood pressure were assessed at baseline and during follow up examinations. Dietary patterns were derived using principal component analysis (PCA). Healthy eating index (HEI) and dietary approach to stop hypertension (DASH) score were measured based on dietary recommendations. Time-dependent Cox models adjusting for confounders were used to examine the association between dietary patterns and the risk of hypertension.

Results
During follow-up, a total of 727 incident cases of hypertension were identified. The mean ± SD age at baseline was 40.3 ± 13.5 and 37.9 ± 12.1 years in men and women, respectively. Two dietary patterns (the healthy and unhealthy) were extracted by PCA. Compared with participants in the first quartile, a 23% (HR: 1.23; 95%CI 1.00–1.53; P trend: 0.056) increased risk of hypertension was found in the fourth quartile of HEI score. This association was disappeared after further adjustment for confounders. Increasing DASH score, the healthy and unhealthy dietary pattern were not associated with risk of hypertension.

Conclusion
Our findings showed that higher adherences to the posteriori- and priori-dietary patterns were not associated with risk of hypertension in this population.
COVID-19 myopericarditis with cardiac tamponade in the absence of respiratory symptoms: a case report
Authors: Cairns Lauren , Abed El Khaleq Yazeed , Storrar Will , Scheuermann-Freestone Michaela 
Published: January 2021

Abstract
Background
Previous reports have shown various cardiac complications to be associated with COVID-19 including: myocardial infarction, microembolic complications, myocardial injury, arrythmia, heart failure, coronary vasospasm, non-ischemic cardiomyopathy, stress (Takotsubo) cardiomyopathy, pericarditis and myocarditis. These COVID-19 cardiac complications were associated with respiratory symptoms. However, our case illustrates that COVID-19 myopericarditis with cardiac tamponade can present without respiratory symptoms.

Case presentation
A 58-year-old Caucasian British woman was admitted with fever, diarrhoea and vomiting. She developed cardiogenic shock and Transthoracic echocardiogram (TTE) found a pericardial effusion with evidence of cardiac tamponade. A nasopharyngeal swab showed a COVID-19 positive result, despite no respiratory symptoms on presentation. A pericardial drain was inserted and vasopressor support required on intensive treatment unit (ITU). The drain was removed as she improved, an antibiotic course was given and she was discharged on day 12.

Conclusions
Our case demonstrates that patients without respiratory symptoms could have COVID-19 and develop cardiac complications. These findings can aid timely diagnosis of potentially life-threatening COVID-19 myopericarditis with cardiac tamponade.
Smartphone / smartwatch-based cuffless blood pressure measurement : a position paper from the Korean Society of Hypertension
Authors:   on behalf of the Korean Society of Hypertension, Lee Hae Young , Lee Dong-Ju , Seo Jongmo , Ihm Sang-Hyun , Kim Kwang-il , Cho Eun Joo , Kim Hyeon Chang , Shin Jinho , Park Sungha , Sohn Il-Suk , Chung Wook-Jin , Ryu Sung Kee , Sung Ki Chul , Kim Juhan , Kim Dae-Hee , Pyun Wook Bum 
Published: January 2021

AbstractSmartphone technology has spread rapidly around the globe. According to a report released by the Korea Information Society Development Institute, about 95% of Koreans aged more than 30 years old owned smartphones. Recently, blood pressure (BP) measurement using a photoplethysmography-based smartphone algorithm paired with the smartwatch is continuously evolving. In this document, the Korean Society of Hypertension intends to remark the current results of smartphone / smartwatch-based BP measurement and recommend optimal BP measurement methods using a smartphone device. We aim to increase the likelihood of success in implementing these new technologies into improved hypertension awareness, diagnosis, and control.
Cargo transport through the nuclear pore complex at a glance
Authors: Paci Giulia , Caria Joana , Lemke Edward A. 
Published: January 2021

ABSTRACT
Bidirectional transport of macromolecules across the nuclear envelope is a hallmark of eukaryotic cells, in which the genetic material is compartmentalized inside the nucleus. The nuclear pore complex (NPC) is the major gateway to the nucleus and it regulates nucleocytoplasmic transport, which is key to processes including transcriptional regulation and cell cycle control. Accordingly, components of the nuclear transport machinery are often found to be dysregulated or hijacked in diseases. In this Cell Science at a Glance article and accompanying poster, we provide an overview of our current understanding of cargo transport through the NPC, from the basic transport signals and machinery to more emerging aspects, all from a ‘cargo perspective’. Among these, we discuss the transport of large cargoes (&gt;15 nm), as well as the roles of different cargo properties to nuclear transport, from size and number of bound nuclear transport receptors (NTRs), to surface and mechanical properties.
Financial Reporting and Entrepreneurial Finance: Evidence from Equity Crowdfunding
Authors: Donovan John 
Published: January 2021

I study the role of accounting and financial reporting in entrepreneurial finance by examining whether financial statement disclosure increases capital raised through equity crowdfunding. On average, I find a positive association between financial reporting and capital raised, suggesting that accounting reduces information asymmetry with potential investors. Additionally, the importance of financial reporting in equity crowdfunding varies predictably in the cross-section. Specifically, financial reporting is associated with greater capital raised when the firm has longer historical operations, during periods of higher macroeconomic uncertainty, and when complemented by detailed shareholder agreements. Finally, using a mediation analysis, I find evidence that financial reporting is indirectly associated with better ex post performance by increasing the likelihood of raising capital. These results provide insight into the role of financial reporting in entrepreneurial finance and inform the ongoing debate over regulation and disclosure in the equity crowdfunding market. This paper was accepted by Brian Bushee, accounting.
Имя собственное в составе современных белорусских пословиц на фоне чешских паремий
Authors: Bojewa Наталия Е. 
Published: January 2021

Имя собственное – важный объект анализа при сравнении пословиц на материале разных языков и культур. Объектом исследования являются чешско-белорусские пословичные параллели с компонентом-именем собственным. Некоторые исследования посвящены вопросу об именах собственных в составе чешских и белорусских паремий и их роли в формировании стереотипов, но в данной работе этот вопрос рассматривается в новом аспекте. Цель исследования – сравнить имена собственные в современных чеш-ских и белорусских пословицах; выявить культурные коннотации имен собственных в паремиях, а также выявить лакуны в белорусском Паремиологическом фонде современных активных пословиц.
Pneumocystis Jirovecii Pneumonia in a Kidney Transplant Recipient 13 Months after Transplantation: A Case Report and Literature Review
Authors: Varnas Dominykas , Jankauskienė Augustina 
Published: January 2021

Background. Pneumocystis jirovecii pneumonia (PCP) is an opportunistic and prevalent fungal infection in immunocompromised hosts, including patients after kidney transplantation (KTx). It is a life threatening infection. While with effective prophylaxis it became less common, it still remains an issue among solid organ transplant (SOT) recipients during the first year. There are no specific clinical signs for PCP. Computed tomography (CT) is a better method for detecting PCP, but definite diagnosis can only be made by identification of the microorganism either by a microscopy or by a polymerase chain reaction (PCR).Clinical case. We present a case of a 17 year old with severe PCP 13 months after KTx followed by reduction in kidney function and respiratory compromise. The pathogen was detected by PCR from bronchoalveolar lavage fluid (BALF) and patient was treated successfully with trimethoprim-sulfamethoxazole (TMP-SMX). Patient’s condition, respiratory status and kidney function gradually improved. Our presented case is unusual because patient had no known risk factors for PCP and he was more than one year after KTx, what is considered rare. In addition patient and his parents delayed in notifying the treating physician about ongoing symptoms because did not deem them important enough.Conclusions. Clinicians treating patients in risk groups for PCP must always remain vigilant even in era of effective prophylaxis. The vigilance should also extend to the patient and patient’s family.
PURIFICATION OF PHOSPHOGYPSUM FOR USE AS CEMENT RETARDER BY SULPHURIC ACID TREATMENT
Authors: Phuong Dang Ngoc , Chi Ngo Kim , Lam Tran Dai , Truyen Chu Quang , Kien Tran Trung , Dinh Dang Thi 
Published: January 2021

Phosphogypsum is a by-product of the wet phosphoric acid production. In this study, chemical compositions of phosphogypsum waste (PG) in Hai Phong diammonium phosphate plant (DAP1) and Lao Cai diammonium phosphate plant (DAP2) in Vietnam were surveyed for the purpose of gypsum recovery by P2O5, F removal to meet TCVN11833 for use treated gypsum as cement retarder. Studies of impurities P2O5, F, TOC removal by sulfuric acid 10 % at 28 0C was presented. The results found that the combination of a low concentration of sulfuric acid treatment, washing, lime neutralizing, and thermal treatment was successful in Phoshogypsum treatment for use as cement retarder. The cement test proved that treated PG could partially replace natural gypsum as a retarder.Keywords: phosphogypsum treatment, phosphorus pentoxide removal, calcium sulfate transition phase, cement retarder.
REMOVAL OF ORGANIC MATTERS FROM PIGGERY WASTEWATER IN ANAEROBIC MOVING BED BIOFILM REACTOR (MBBR)
Authors: Nguyen Quan Truong , Nguyen Quan Truong , Nguyen Ha Thi 
Published: January 2021

The objective of this study is to investigate the performance of Anaerobic Moving Bed Biofilm Reactor (MBBR) on the removal of organic matters (using COD and TSS values) in piggery wastewater using two kinds of carrier: Polyurethane (PU) and Polyethylene (PE) - Different organic loading rates (OLRs) varying from 4 to 10 gCOD/l/day with controlled temperature 37±2oC, pH 7.0-7.5 were investigated. The seeded sludge was collected at the anaerobic tank of the wastewater treatment plant of the Sabeco Beer Manufacturing Plant (Nam Tu Liem district, Hanoi) and grown in the MBBR for 15 days. For porous PU material, the COD and TSS removal efficiencies achieved 69.7 and 67.3% and 54.9 and 65.5% at OLR 4 and 6 gCOD/l/day, respectively. Whereas for wheel shape PE material, it was found that the COD removal efficiencies were slightly higher with OLR of 6 gCOD/l/day (71%%), even with higher OLR at 10 gCOD/l.day, the COD removal efficiency didn‘t seem to significantly increase (73.3 %). For TSS removal, in comparison between PU and PE, the later found slightly better with the same OLRs of 4 and 6 gCOD/l/day, reaching 63.2 and 67 %, respectively. However, TSS removal efficiencies were found to be higher with PE carrier at higher OLR, reaching 72% at 10 gCOD/l/day.
Gente de bem protesta aos domingos: Uma análise de imagens postadas com a ‘hashtag’ #dia26euvou
Authors: Figueiredo Carolina 
Published: January 2021

Após a eleição presidencial de 2014, nota-se uma ampliação da polarização entre direita e esquerda no Brasil. Por estarem relacionados às gestões do presidente Luís Inácio Lula da Silva e da presidenta Dilma Rousseff, os ideais de esquerda passaram a ser preteridos. O presente artigo analisa a construção de uma narrativa que deslegitima os protestos da esquerda, classificando-os como hostis. Para as finalidades aqui pretendidas, usamos o caso do protesto de 26 de maio de 2019. Seguimos a hashtag #dia26euvou por um período de 24 horas, analisando imagens que revelam o antagonismo em relação às manifestações de esquerda.
Implementation of Business Competition Violation Norms in the Decision of the Business Competition Supervision Commission
Authors: Ma’ruf Arifin , Setiyawan Wahyu Beny Mukti , Widiatama Widiatama 
Published: January 2021

<table width="680" border="1" cellspacing="0" cellpadding="0" align="left"><tbody><tr><td valign="top" width="487"><p><strong>This paper analyzes the application of norms concerning violations of business competition in KPPU decisions. The case study in this paper is in the case of violations of business competition conducted by PT Forisa Nusapersada in Case Decision Number 14/KPPU-L/2015. As a comparison, this study also compares the application of norms in cases that are almost similar, namely the Decision of the Case KPPU Number 14/ KPPU-L/ 2015 with the Decision of the Case KPPU Number: 06/KPPU-L/2004. The results of the research show that in addition to Article 19 and Article 25 above, KPPU should also apply Article 52 paragraph (2) letter a and Article 15 paragraph (3) of Law Number 5 of 1999 concerning Prohibition of Monopolistic Practices and Unfair Business Competition in the case of PT Forisa Nusapersada.</strong><strong></strong></p><p><strong> </strong></p></td></tr></tbody></table>
DAFTAR ISI Volume 3, Nomor 2, November 2020.
Authors: Kunto Imbar 
Published: January 2021

Ummu Kulsum Wiyarandi, Dr. KHAERUDIN, M.Pd, & Diana Ariani, S.Pd., M.Pd. (2020). Pengembangan Kurikulum Program Tahfidz Al-Qur’an di Pondok Qur’an Bahrul Ulum Bogor . Jurnal Pembelajaran Inovatif, 3(2), 79 - 87. https://doi.org/10.21009/JPI.032.01
Fahrenza, R., Cecep Kustandi, & Kunto Imbar Nursetyo. (2020). Pengembangan Modul Belajar Bahasa Mandarin di BLK PT Trias Insan Madani. Jurnal Pembelajaran Inovatif, 3(2), 88 - 96. https://doi.org/10.21009/JPI.032.02.
Mariliana Berlian, Suprayekti, & Retno Widyaningrum. (2020). Pengembangan Strategi Pembelajaran Menyenangkan “Permainan Bisik Berantai” Pada Pembelajaran Bahasa Inggris Kelas II di SD Mardi Yuana. Jurnal Pembelajaran Inovatif, 3(2), 97 - 103. https://doi.org/10.21009/JPI.032.03.
Zuraida, A. H. M. B., Suprayekti, & Retno Widyaningrum. (2020). Desain Program Pelatihan “Pengenalan Dasar-Dasar Asuransi” Untuk Karyawan Baru Pada PT ASABRI (Persero) . Jurnal Pembelajaran Inovatif, 3(2), 104 - 112. https://doi.org/10.21009/JPI.032.04.
Imam, A., Cecep Kustandi, & Retno Widyaningrum. (2020). Pengembangan Blended Learning untuk Mata Kuliah Pengembangan Media Sederhana Teknologi Pendidikan. Jurnal Pembelajaran Inovatif, 3(2), 113 - 122. https://doi.org/10.21009/JPI.032.05.
Rahmi Citra Lestari, Mulyadi, M.Pd, & Kunto Imbar Nursetyo, S.Pd. (2020). Evaluasi Reaksi Dalam Pelaksanaan Program Cool Class Di BTPN Syariah. Jurnal Pembelajaran Inovatif, 3(2), 123 - 131. https://doi.org/10.21009/JPI.032.06.
QD, A., Kustandi, C., & Imbar, K. (2020). Kajian Pengembangan Web HyLearn oleh Dosen Fakultas Ilmu Pendidikan Universitas Negeri Jakarta. Jurnal Pembelajaran Inovatif, 3(2), 132 - 139. https://doi.org/10.21009/JPI.032.07.
Defrian Putut Wasitto. (2020). Evaluasi pelatihan peningkatan kompetensi TIK Pustekkom untuk guru di Papua dan Papua Barat. Jurnal Pembelajaran Inovatif, 3(2), 140 - 143. https://doi.org/10.21009/JPI.032.08.
Ariani, D. (2020). Gamifikasi untuk Pembelajaran. Jurnal Pembelajaran Inovatif, 3(2), 144 - 149. https://doi.org/10.21009/JPI.032.09.
Mariyana, R. (2020). Pengembangan Desain Model Pembelajaran Virtual Flipped Classroom. Jurnal Pembelajaran Inovatif, 3(2), 150 - 156. https://doi.org/10.21009/JPI.032.10.
Patient with Multiple Rib Fractures Developed into Phrenic Hernia after Cardiopulmonary Resuscitation
Authors: Cheng Shaowen , Yang Jian , Peng Lei , Chen Yangping , Hu Zhihua 
Published: January 2021

Abstract
Background: Phrenic hernia is a rare condition in patients with multiple rib fractures after cardiopulmonary resuscitation. We report a 28-year-old case of multiple injuries with multiple rib fractures who developed Phrenic hernia after cardiopulmonary resuscitation. Case presentation: We report a case of a young woman who developed sudden respiratory and cardiac arrest during treatment in the intensive care unit with severe multiple injuries with multiple fractures of the left rib. The patient developed a left diaphragmatic hernia after cardiopulmonary resuscitation, causing the stomach and part of the liver to enter the left chest. After emergency operation, the patient was in stable condition and finally recovered and discharged from hospital.Conclusion: It is easy to cause diaphragmatic hernia in the process of cardiopulmonary resuscitation for patients with rib fracture, but sometimes it is necessary to carry out cardiopulmonary resuscitation before saving the patient's life. Once diagnosed with diaphragmatic hernia, surgical treatment should be done as soon as possible to avoid organ necrosis.
A Modified Regularization Approach to MIT Image Reconstruction Based on PSO-SA
Authors: Lu Tian , Yang Dan , Wang Xu , Zhang Xinhui , Guo Wenxin 
Published: January 2021

Abstract
Background: Magnetic induction tomography (MIT) is a promising imaging modality of electrical tomography. The precision of image reconstruction algorithms in MIT places the key role in its application in industrial and biomedical fields. Image reconstruction in MIT is an ill-posed inverse problem. Regularization algorithms are effective to handle the ill-posed problem. However it is difficult to select its proper regularization parameter, larger or smaller regularization parameter will both effect on the quality of the reconstructed images.Methods: In this paper, firstly, the regularization principle of image reconstruction of MIT is analyzed. Then, we take the dimension of the Hessian matrix as the prior knowledge to obtain a novel penalty term, and add it to hybrid regularization algorithm, including Tikhonov and NOSER regularization, to propose a modified hybrid regularization algorithm. Secondly, selection for regularization parameters of image reconstruction algorithm is considered as a typical optimization problem, Particle swarm optimization with simulated annealing (PSO-SA) algorithm is used to solve the optimal solution.Results: Numberial experiments with six typical models and cerebral hemorrhage model were carried out. The correlation coefficient (CC), relative error (RE) and condition number of Hessian matrix are used as evaluation metrics to evaluate the effectiveness of the proposed method. The results obtained from the proposed method have lower REs and higher CCs compared to the other two methods. And the condition number of Hessian matrix in the proposed method is greatly reduced.Conclusions: The experimental results can prove the validity of the proposed method. The proposed method is capable of enhancing accuracy and noise immunity, which most closely coincides with the true conductivity distributions. Our method has better reconstructed quality compared with the other two methods, and it provides a theoretical reference for the development of application of the MIT technique in clinical decision application.