bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent changes in mountain hay meadows of high conservation value in eastern France
Authors: Nicod Corentin , Gillet François 
Published: March 2021

AbstractAimTo assess vegetation changes in mountain hay meadows of high conservation value over 15 years.LocationJura Mountains and Vosges Mountains (France).MethodsIn 2019, we resampled old phytosociological relevés (made from 2005 to 2009) in extensive mountain hay meadows. To detect shifts in composition from old to recent relevés, we performed a permutational multivariate analysis of variance, and visualized observed patterns using non‐metric multidimensional scaling on the Bray–Curtis dissimilarity matrix of the vegetation data. We tested for differences in taxonomic, functional and phylogenetic diversity metrics, CSR strategies and ecological indicator values using paired Wilcoxon–Mann–Whitney tests.ResultsNon‐metric multidimensional scaling paired with a permutational multivariate analysis of variance showed that, overall, old and recent plant communities were not different in the Vosges Mountains, contrary to the situation in the Jura Mountains. Wilcoxon–Mann–Whitney paired tests revealed that, in the Jura Mountains, plant communities underwent a significant decrease in taxonomic, functional and phylogenetic diversity, associated with an increase of ruderal and competitive strategies. Ecological indicator values for nutrient availability and defoliation tolerance both increased, suggesting an intensification of agricultural practices. In the Vosges Mountains, only species richness increased while the inverse Simpson index and Pielou evenness decreased.ConclusionsOur results show that plant diversity is not currently threatened in the studied grasslands in the Vosges Mountains. By contrast, in the studied grasslands in the Jura Mountains, plant diversity is declining. The situation in the Vosges shows that agricultural activities and biodiversity conservation can be reconciled. This situation should be further investigated to help resolve conflicts between agriculture and biodiversity conservation in semi‐natural grasslands.
Assessing the importance of reproductive modes for the evaluation of altitudinal distribution patterns in tropical frogs
Authors: Siqueira Carla C. , Vrcibradic Davor , Almeida‐Gomes Mauricio , Rocha Carlos Frederico D. 
Published: March 2021

AbstractAltitudinal patterns in species richness vary among taxa and are shaped by the intrinsic traits of different organisms and their response to environmental variables. We evaluated the relationship between anuran richness and elevation along local and regional altitudinal gradients within the Brazilian Atlantic Forest based on data from fieldwork (local dataset; 100–1900 m a.s.l.) and on compiled secondary information (regional dataset; 0–2300 m a.s.l.). We also tested whether frog distribution patterns were consistent with the predictions of the mid‐domain (MDE) and Rapoport effects. In each analysis, we also considered the impact of reproductive mode, classified here as either water‐dependent or water‐independent, on species richness patterns. Considering the local dataset, species richness decreased with increasing altitude for all species pooled and (more strongly) for the species with water‐dependent reproductive mode, whereas the water‐independent species presented increased richness at intermediate altitudes. For the regional dataset, richness peaked at intermediate altitudes in all three cases. At the local scale, the observed patterns (except for the water‐dependent species) fit the MDE model, whereas at the regional scale, there was no fit in any case. Neither local nor regional data were consistent with the predictions of the Rapoport rule. Our findings indicate a strong influence of reproductive mode on the altitudinal distribution of tropical frogs, and that distribution patterns may vary according to the spatial scale considered. This highlights the importance of taking life‐history traits into consideration when assessing the distribution patterns of tropical frog species along environmental gradients.Abstract in Portuguese is available with online material.
Assessing Environmental Acidity in Storerooms of Natural History Collections
Authors: Pérez‐Azcárate Marta , Caballero‐López Berta , Uribe Francesc , Ibáñez Neus , Masó Glòria , Garcia‐Franquesa Eulàlia , Carrillo‐Ortiz José , Agua Fernando , García‐Heras Manuel , Villegas María‐Ángeles 
Published: March 2021

AbstractOutdoor and indoor pollutants can affect the conservation of natural history collections. As a first approach to this question, environmental acidity around specimens in the collections of the Natural Science Museum of Barcelona and Botanic Institute of Barcelona (MCNB‐IBB) was measured. Measurements were taken using optical sensors in a number of different places: inside and outside buildings, in storerooms, on store cases and cabinets and in containers in three collections. All acidity measurements fell within a pH range of 6.5–7.7, which suggests that the collections tested were not exposed to a dangerous acidic environment during the measurement period. Despite its outdated facilities, the Museum’s buildings and storerooms act as effective barriers against acid pollutants entering from the outside. The type of storage facilities and containers employed seems to have little impact but is still nevertheless of some relevance. Optical sensors are excellent tools for disentangling the complex spatio‐temporal environments in which the MCNB‐IBB collections are housed. Larger samples will be necessary if a more complete analysis is to be undertaken.
Seller reputation and price gouging: Evidence from the COVID‐19 pandemic
Authors: Cabral Luís , Xu Lei 
Published: March 2021

AbstractFrom mid‐January to March 2020, 3M masks sold on Amazon by third party sellers were priced 2.4 times higher than Amazon's 2019 price. However, this price increase was not uniform across sellers. We estimate that when Amazon is stocked out (one of our measures of scarcity) new (entrant) sellers increase price by 178%, whereas the continuing sellers' increase is limited to 56.7%. This is consistent with the idea that seller reputation limits the extent of profitable price gouging. Similar results are obtained for Purell hand sanitizer and for other measures of scarcity. We also explore policy implications of our results.
Neurological outcome and quality of life 3 months after COVID‐19: A prospective observational cohort study
Authors: Rass Verena , Beer Ronny , Schiefecker Alois Josef , Kofler Mario , Lindner Anna , Mahlknecht Philipp , Heim Beatrice , Limmert Victoria , Sahanic Sabina , Pizzini Alex , Sonnweber Thomas , Tancevski Ivan , Scherfler Christoph , Zamarian Laura , Bellmann‐Weiler Rosa , Weiss Günter , Djamshidian Atbin , Kiechl Stefan , Seppi Klaus , Loeffler‐Ragg Judith , Pfausler Bettina , Helbok Raimund 
Published: March 2021

AbstractBackground and purposeTo assess neurological manifestations and health‐related quality of life (QoL) 3 months after COVID‐19.MethodsIn this prospective, multicenter, observational cohort study we systematically evaluated neurological signs and diseases by detailed neurological examination and a predefined test battery assessing smelling disorders (16‐item Sniffin Sticks test), cognitive deficits (Montreal Cognitive Assessment), QoL (36‐item Short Form), and mental health (Hospital Anxiety and Depression Scale, Posttraumatic Stress Disorder Checklist–5) 3 months after disease onset.ResultsOf 135 consecutive COVID‐19 patients, 31 (23%) required intensive care unit (ICU) care (severe), 72 (53%) were admitted to the regular ward (moderate), and 32 (24%) underwent outpatient care (mild) during acute disease. At the 3‐month follow‐up, 20 patients (15%) presented with one or more neurological syndromes that were not evident before COVID‐19. These included polyneuro/myopathy (n = 17, 13%) with one patient presenting with Guillain‐Barré syndrome, mild encephalopathy (n = 2, 2%), parkinsonism (n = 1, 1%), orthostatic hypotension (n = 1, 1%), and ischemic stroke (n = 1, 1%). Objective testing revealed hyposmia/anosmia in 57/127 (45%) patients at the 3‐month follow‐up. Self‐reported hyposmia/anosmia was lower (17%) at 3 months, however, improved when compared to the acute disease phase (44%; p < 0.001). At follow‐up, cognitive deficits were apparent in 23%, and QoL was impaired in 31%. Assessment of mental health revealed symptoms of depression, anxiety, and posttraumatic stress disorders in 11%, 25%, and 11%, respectively.ConclusionsDespite recovery from the acute infection, neurological symptoms were prevalent at the 3‐month follow‐up. Above all, smelling disorders were persistent in a large proportion of patients.
Growth parameters, longevity, and mortality of the seabob shrimp Xiphopenaeus spp. (Decapoda: Penaeidae) in four important fishing regions of southeastern Brazil
Authors: Miazaki Lizandra Fernandes , Heckler Gisele Salgado , Santos Ana Paula Freitas , Castilho Antonio Leão , Pescinelli Régis Augusto , Costa Rogerio Caetano 
Published: March 2021

AbstractWe investigated and compared growth parameters, longevity, mortality (total, natural, and fishing), and exploitation rates of the seabob shrimp Xiphopenaeus spp. in four important fishing regions of southeastern Brazil. The hypothesis that the growth and mortality characteristics of distinct populations differ along a latitudinal gradient was tested. Sampling was performed monthly in Macaé, Ubatuba, Santos/São Vicente, and Cananéia over a 1‐ to 2‐year period. Growth and longevity parameters were estimated by the von Bertalanffy growth equation models. Total mortality (Z) was estimated by length‐converted catch curves. Growth parameters differed between sexes: males reached smaller sizes, showed larger growth coefficients (k) and higher mortality, and lived less than females in the four studied regions. Rather than finding a latitudinal gradient, our results support the hypothesis that distinct local environmental characteristics and fishing pressures alter the growth and population dynamics of Xiphopenaeus spp. in different areas. Our study indicates that the stocks of Xiphopenaeus spp. are overexploited, highlighting the importance of management plans to prevent the collapse of stocks and maintain them at sustainable levels for long‐term exploitation.
2. DESPITE SINGULARITY: THE EVENT AND ITS MANIFOLD STRUCTURES OF REPETITION
Authors: ESPOSITO FERNANDO 
Published: March 2021

ABSTRACTThis article's principle interest is in the “structures of repetition” that characterize supposedly singular events. The starting point for the analysis is Reinhart Koselleck's discussion of the event in “Structures of Repetition in Language and History.” Koselleck perceived events as arising from metahistorical structures that characterize all human histories regardless of the eras in which they took place and are narrated. This article scrutinizes Koselleck's understanding of the event as well as the underlying “structures of repetition” shaping it. In considering the question of the temporality of the event, this article distinguishes three strata of repetitive structures. First, it examines a seemingly trivial historiographical structure of repetition of the event, which is the iterative proclamation of the return of the event. It then analyzes Koselleck's foundational, yet rarely truly appreciated, “Structures of Repetition in Language and History” and maps out the fundamental structures of repetition, which are the conditions of possibility of events. Finally, it hints at a further linguistic stratum of repetitive structures. In light of growing interest in Koselleck's work in both German and Anglophone historiography, this article systematizes the manifold structures of repetition against the backdrop of current explorations of the event's temporality, thus surveying a facet of Koselleck's pioneering work that is too often forgotten.
Fever of unknown origin (FUO) on a land on cross‐roads between Asia and Europa; a multicentre study from Turkey
Authors: Yenilmez Ercan , Kakalicoglu Deniz , Bozkurt Fatma , Filiz Mine , Akkol Camurcu Aysegul , Damar Midik Elif Ozge , Berk Cam Hande , Arkali Eren , Bilgic Atli Seval , Sahin Ahmet , Yorulmaz Goktas Sibel , Erkan Halil , Ceylan Mehmet Resat , Kacar Eker Merve , Kaya Hava , Karacaer Zehra , Tural Ersin , Dokmetas İlyas , Gorenek Levent , Kose Sukran 
Published: March 2021

AbstractAimsThe differential diagnosis of Fever of Unknown Origin (FUO) is still a major clinical challenge despite the advances in diagnostic procedures. In this multicentre study, we aimed to reveal FUO aetiology and factors influencing the final diagnosis of FUO in Turkey.MethodsA total of 214 patients with FUO between the years 2015 and 2019 from 13 tertiary training and research hospitals were retrospectively evaluated.ResultsThe etiologic distribution of FUO was infections (44.9%), malignancies (15.42%), autoimmune/inflammatory (11.68%) diseases, miscellaneous diseases (8.41%) and undiagnosed cases (19.62%). Brucellosis (10.25%), extrapulmonary tuberculosis (6.54%) and infective endocarditis (6.54%) were the most frequent three infective causes. Solid malignancies (7.1%) and lymphoma (5.6%), adult‐onset still's disease (6.07%) and thyroiditis (5.14%) were other frequent diseases. The aetiological spectrum did not differ in elderly people (P < .05). Infections were less frequent in Western (34.62%) compared with Eastern regions of Turkey (60.71%) (P < .001, OR: 0.31, 95% Cl: 0.19 to 0.60). The ratio of undiagnosed aetiology was significantly higher in elderly people (p: 0.046, OR: 2.34, 95% Cl: 1.00 to 5.48) and significantly lower in Western Turkey (P: .004, OR: 3.07, 95% Cl: 1.39 to 6.71).ConclusionsBrucellosis, extrapulmonary tuberculosis and infective endocarditis remain to be the most frequent infective causes of FUO in Turkey. Solid tumours and lymphomas, AOSD and thyroiditis are the other common diseases. The aetiological spectrum did not differ in elderly people, on the other hand, infections were more common in Eastern Turkey. A considerable amount of aetiology remained undiagnosed despite the state‐of‐the‐art technology in healthcare services.
The role of social identity in the explanation of collective action: An intergroup perspective on the Yellow Vests movement
Authors: Adam‐Troian Jaïs , Mahfud Yara , Urbanska Karolina , Guimond Serge 
Published: March 2021

AbstractSocial psychologists have developed influential theoretical models to understand intergroup conflicts, radicalism, and collective action. November 2018 saw the emergence of a new powerful movement in France named the Yellow Vests. Born on social media, the movement has sustained an unprecedented period of intense protests and violent clashes with the police, challenging the French government. As such, this movement offers an ideal context to examine the real‐world relevance of current social‐psychological theorizing. Using a social identity and self‐categorization perspective, two correlational studies (three samples, N = 1,849) tested the role of self‐categorization as a group member, or social identity, in accounting for individual participation in normative and nonnormative collective action. Using different operationalizations of identification, both studies confirm a powerful role of identification as a Yellow Vest and provided evidence that the effect of social media use on collective action is fully mediated by self‐categorization as a Yellow Vest. An alternative model suggesting that social media use mediated the relation between social identity and collective action was not supported by the data.
Functional characterization of Copy Number Variations regions in Djallonké sheep
Authors: Goyache Félix , Fernández Iván , Tapsoba Arnaud Stephan R. , Traoré Amadou , Menéndez‐Arias Nuria A. , Álvarez Isabel 
Published: March 2021

AbstractA total of 184 Djallonké (West African Dwarf) sheep of Burkina Faso were analysed for Copy Number Variations (CNV) using Ovine 50 K SNP BeadChip genotyping data and two different CNV calling platforms: PennCNV and QuantiSNP. Analyses allowed to identify a total of 63 candidate Copy Number Variations Regions (CNVR) on 11 different ovine chromosomes covering about 82.5 Mb of the sheep genome. Gene‐annotation enrichment analysis allowed to identify a total of 751 potential candidate ovine genes located in the candidate CNVR bounds. Functional annotation allowed to identify five statistically significant Functional Clusters (FC; enrichment factor > 1.3) involving 61 candidate genes. All genes forming significantly enriched FC were located on ovine chromosome (OAR) 21. FC1 (22 genes including PAG4 and PAG6) and FC5 (three genes: CTSC, CTSW and CTSF), coding proteases (peptidases and cathepsins, respectively), were involved in reproductive performance and modulation of gestation. Both FC3 and FC4 were involved in inflammatory and immunologic response through coding serum amyloid A and B‐box‐type zinc finger proteins, respectively. Finally, FC2 consisted of 27 genes (including OR10G6 and OR8B8) involved in olfactory receptor activity, key for animals adapting to new food resources. CNVR identified on at least 15% of individuals were considered CNVR hotspots and further overlapped with previously reported quantitative trait loci (QTL). CNVR hotspots spanning genes putatively involved with lipid metabolism (SKP1, TCF7, JADE2, UBE2B and SAR1B) and differential expression in mammary gland (SEC24A and CDKN2AIPNL) on OAR5 and dairy traits (CCDC198 and SLC35F4) on OAR7 overlapped with QTL associated with lipid metabolism, milk protein yield and milk fat percentage. Information obtained from local sheep populations naturally adapted to harsh environments contributes to increase our understanding of the genomic importance of CNV.
Delaying elaborated feedback within computer‐based learning environments: The role of summative and question‐based feedback
Authors: Candel Carmen , Máñez Ignacio , Cerdán Raquel , Vidal‐Abarca Eduardo 
Published: March 2021

AbstractElaborative feedback (EF) containing explanations on students' responses benefits learning. Computer‐based environments provide learners with EF in different ways, for example, on an immediate question‐by‐question basis or after answering a set of questions. Recent findings also suggest that delaying EF enhances learning. However, it is unclear to what extent different types of delayed‐EF favour students' performance. This study examines whether and how two types of delayed‐EF (question‐based vs. summative) influence students' question‐answering performance and final learning over immediate‐EF. One hundred thirty‐three secondary‐school students read a scientific text and answered 12 multiple‐choice questions in a computer‐based environment. A day later, students completed a final learning test with 20 open‐ended questions. Results showed that neither question‐based delayed EF nor summative delayed EF outperformed immediate EF. However, EF moderated the relationship between students' prior knowledge and their performance outcomes, suggesting that students with higher levels of prior knowledge receiving summative delayed EF benefited more.
The mechanisms of left septal and anterior wall reentrant atrial tachycardias analyzed with ultrahigh resolution mapping: The role of functional block in the circuit
Authors: Miyazaki Shinsuke , Hasegawa Kanae , Ishikawa Eri , Mukai Moe , Aoyama Daisetsu , Nodera Minoru , Yamaguchi Junya , Shiomi Yuichiro , Tama Naoto , Ikeda Hiroyuki , Fukuoka Yoshitomo , Ishida Kentaro , Uzui Hiroyasu , Tada Hiroshi 
Published: March 2021

AbstractBackgroundLow voltage areas (LVAs) are most commonly observed on the left atrial (LA) septal/anterior wall.ObjectiveWe explored the mechanisms of LA septal/anterior wall reentrant tachycardias (LASARTs) using ultrahigh resolution mapping.MethodsThis study included seven consecutive LASARTs in six patients (75 [62.2–82.8] years, 4 women) who underwent atrial tachycardia (AT) mapping and ablation using Rhythmia systems.ResultsThe AT cycle length was 266 (239–321) ms. During ATs, 11.0 (9.0–12.9) cm2 of LVAs were identified in all, and 0.8 (0.7–1.7) cm2 of dense scar was identified in four patients. Five ATs rotated around dense scar, while two rotated around functional linear block, which was confirmed during atrial pacing after AT termination. The AT circuit length was 8.7 ± 2.1 cm with a conduction velocity of 30.4 ± 3.7 cm/s. A median of 3.0 (2.0–4.0) slow conduction areas per circuit were identified, and 17/23 (73.9%) areas were present in LVAs, while they were at the border of the LVA and normal voltage areas in the remaining 6/23 (26.1%). Global activation histograms facilitated the identification of the critical isthmus in all. Tailor‐made ablation at critical isthmuses successfully eliminated all ATs. However, one patient with AT related to functional linear block experienced recurrent AT related to dense scar, which progressed after the procedure. During a mean 14 ± 13 month follow‐up after the last procedure, no patients experienced recurrent ATs without any complications.ConclusionLASARTs consist of not only fixed conduction blocks but also functional conduction blocks. Ultrahigh resolution mapping is highly useful to decide the optimal tailor‐made ablation strategy based on the mechanisms.
LncRNA TP73‐AS1 enhances the malignant properties of pancreatic ductal adenocarcinoma by increasing MMP14 expression through miRNA ‐200a sponging
Authors: Miao Haiyan , Lu Jingjing , Guo Yibing , Qiu Hongquan , Zhang Yu , Yao Xihao , Li Xiaohong , Lu Yuhua 
Published: March 2021

AbstractPancreatic ductal adenocarcinoma (PDAC) is an invasive and aggressive cancer that remains a major threat to human health across the globe. Despite advances in cancer treatments and diagnosis, the prognosis of PDAC patients remains poor. New and more effective PDAC therapies are therefore urgently required. In this study, we identified a novel host factor, namely the LncRNA TP73‐AS1, as overexpressed in PDAC tissues compared to adjacent healthy tissue samples. The overexpression of TP‐73‐AS1 was found to correlate with both PDAC stage and lymph node metastasis. To reveal its role in PDCA, we targeted TP73‐AS1 using LnRNA inhibitors in a range of pancreatic cancer (PC) cell lines. We found that the inhibition of TP73‐AS1 led to a loss of MMP14 expression in PC cells and significantly inhibited their migratory and invasive capacity. No effects of TP73‐AS1 on cell survival or proliferation were observed. Mechanistically, we found that TP73‐AS1 suppressed the expression of the known oncogenic miR‐200a. Taken together, these data highlight the prognostic potential of TP73‐AS1 for PC patients and highlight it as a potential anti‐PDAC therapeutic target.