bluuebunny/crossref_metadata_2025_split huggingface dataset:
Produk Sabun Transparan Berbahan Herbal di Desa Oro-Oro Ombo, Tlekung, Junrejo, Batu Malang, Provinsi Jawa Timur
Authors: Awik Puji Dyah Nurhayati  , Elshinta Riantica  , Noor Nailis Saa’dah  , Edwin Setiawan  , Nova Maulidina Ashari  , Indiani Adik Mayang , Agus Wahyudi  , Ratna Rintaningrum  , Ni Wayan  
Published: January 2021

Pengolahan empon empon di Desa Oro-oro Ombo-Tlekung-Junrejo-Batu Malang, Provinsi Jawa Timur masih sederhana, yaitu hanya dijual dalam kondisi segar atau produk jamu tradisional, belum dilakukan pengembangan teknologi menjadi produk herbal yang bernilai ekonomi tinggi. Solusi yang diajukan dalam kegiatan pengabdian ini adalah inovasi teknologi pembuatan sabun herbal transparan dari jahe merah, lidah buaya dan bunga melati. Metode pembuatan dilakukan dengan teknik saponifikasi. Hasil uji organoleptik dan efektivitas menunjukkan bahwa formulasi sabun yang paling baik adalah total bahan herbal sebanyak 1,5 g yang tersusun oleh 0,5 g ekstrak cair bunga melati; 0,4 g bubuk jahe merah; 0,6 g gel lidah buaya. Kesimpulan dari kegiatan ini bahwa formula sabun transparan yang paling baik adalah formula A yaitu formula ekstrak herbal 1,5 g. Selain itu kegiatan ini mendapat dukungan dari pemerintah Kota Batu, apparat desa dan warga di Desa Oro Oro Ombo
Sosialisasi Pemanfaatan Aplikasi Corona Tracer Untuk Monitoring Jumlah Kasus Covid 19 Pada Mahasiswa Peserta Kuliah Berkarya Bermasyarakat (Kubermas) Universitas Khairun
Authors: Jamil Mohamad , Mufti Amir Sultan  , Fera The  
Published: January 2021

Virus corona yang pertama kali muncul dan menyebar ke manusia berasal dari kota Wuhan, China pada akhir Desember 2019. Setelah ditelusuri, ternyata beberapa orang yang terinfeksi memiliki riwayat yang sama, yaitu mengunjungi pasar basah makanan laut dan hewan lokal di Wuhan. Di Indonesia sendiri, saat ini sudah mencapai 333449 kasus pasien positif virus COVID-19 yang terlacak, dan 11884 lebih masyarakat meninggal karena virus itu. Tujuan dari kegiatan pengabdian ini yaitu untuk memberikan sosialiasasi kepada para mahasiswa peserta kuliah kerja bermasyarakat terkait pemanfaatan aplikasi corona tracker untuk membantu memonitoring jumlah penderita covid baik yang terinfeksi, meninggal dan sembuh. Kegiatan ini dilakukan secara luring dan daring dengan jumlah peserta 1000 mahasiswa, 50 peserta mengikuti secara luring dan sisanya secara daring. Hasil yang didapat dari kegiatan sosialisasi ini yaitu mahasiswa peserta kubermas dapat memahami tata cara penggunaan aplikasi corona tracker dan diharapkan peserta kubermas akan dapat membantu mensosialisasikan aplikasi ini kepada masyarakat di lokasi tempat kubermas mereka nantinya.
Berbagi Berbagi / Memberikan Bantuan Dimasa Pandemi Corona Kepada Masyarakat Yang Diperkirakan Terdampak Covid-19 Di Desa Anjir Seberang Pasar 2 Kabupaten Batola
Authors: Mahfuzil Anwar  , Rezky Nefianthi  , Arfie Yasrie  , Abdul Wahab  
Published: January 2021

Salah satu dari Tridarma Perguruan Tinggi yang ketiga yaitu Pengabdian Kepada Masyarakat yang harus dilakukan bagi para Dosen, banyak hal yang dapat dilakukan seperti misalnya penyuluhan-penyuluhan, pelatihan-pelatihan serta bantuan-bantuan soaial seperti yang dilakukan oleh sebagian dosen yang akan dilaporkan berupa laporan pengabdian masyarakat sebagai bukti bahwa Dosen secara perorangan maupun secara kelompok atau Tim telah melakukan pengabdian kepada masyarakat. Berdasarkan deskripsi permasalahan di atas, dapat disimpulkan bahwa kualitas dan kuantitas Tridarma Perguruan Tinggi salah satunya adalah Pengabdian Kepada Masyaraka merupakan pengembangan profesi dosen dimana kegiatan ini masih sangat dibutuhkan oleh sebagian bagi masyarakat, khususnya yang berkaitan dengan kondisi saat Pandemi Covid-19 ini yang sangat mengganggu berbagai sektor, misalnya sektor kesehatan, sektor ekonomi maupun sektor-sektor lainnya dampak dari Pandemi ini. Dalam sambutannya Ketua Tim Pengabdian Kepada Masyarakat Drs.H. Abdul Wahab, M.Si (STIMI Banjarmasin) berharap agar bantuan ini dapat bermanfaat bagi warga yang membutuhkan dan berdoa semoga Covid-19 ini segera berakhir serta kita sekalian dapat melakukan aktivitas seperti biasanya sebelum wabah Pandemi ini mengganggu kita dalam beraktivitas sebagaimana biasanya. Sebagaimana telah dikemukakan di atas, bahwa perguruan tinggi melalui tenaga pendidiknya (Dosen) mengemban tiga tugas utama atau lebih populer dengan sebutan Tridarma Peguruan Tinggi, yaitu menyelenggarakan Pendidikan, melakukan Penelitian, dan Melaksanakan Pengabdian Kepada Masyarakat. Ketiga darma tersebut harus dilihat sebagai satu kesatuan yang utuh, dan tidak boleh dikotak-kotakkan secara terpisah. Oleh karenanyau, untuk memahami hakikat pengabdian kepada masyarakat, diperlukan pemahaman tentang dua darma yang lain. Tanpa melakukan darma pendidikan dan penelitian, tentu tidak akan ada hasil apapun yang dapat disampaikan kepada masyarakat.
Aplikasi Sistem Informasi Pengolahan Data Administrasi Pada Klinik Mitra Sehat Jakarta Selatan Berbasis Java
Authors: Tamarawati Sely 
Published: January 2021

Aplikasi sistem informasi administrasi menjadi faktor penting dalam sebuah Klinik Mittra Sehat Jakarta Selatan Sistem informasi administrasi klinik dirancang untuk dapat meminimalisir kegiatan manual, dimana petugas masih kesulitan dalam melakukan pencarian nomor rekam medis karena banyak pasien yang tidak membawa kartu berobat. Tujuan penelitian ini adalah untuk mengembangkan sistem informasi pasien di Klinik Mita Sehat, mengurangi kesalahan karena faktor manusia demi memaksimalkan pelayanan kepada pasien. Penelitian ini bertujuan smerancang aplikasi Sistem Administrasi Klinik berbasis web yang terintegrasi meliputi kegiatan registrasi pasien, pengolahan data, pemeriksaan pasien dan data resep obat hingga transaksi pembayaran secara bertahap Dengan adanya apliakasi sistem informasi pada Klinik Mitra Sehat ini dihaapkan dapat memenuhi kebutuhan informasi yang cepat, tepat dan akurat untuk kemajuan Klinik. Aplikasi ini dibuat dengan program Java Netbeans Sedangkan untuk koneksinya dalam database MySQL. Aplikasi ini dapat mempermudah kegiatan administrasi yang meliputi data pasien, data pemeriksaan, serta pelayanan pasien secara bertahap mulai dari proses registrasi hingga transaksi pembayaran.
Preoperative Anxiety and Fear of Anesthesia in Patients admitted in Tertiary Care Hospitals of Rawalpindi
Authors: Mariyam Zahra , Safdar Laibah , Fatima Shafaq , Zaheer Jawad 
Published: January 2021

Background: Preoperative apprehension is a widespread global problem. This anxiety and apprehension can significantly affect all aspects of anesthesia and surgery. Thus, it is essential to detect and address the patient's anxiety to assist in recovery after surgery and improve the patient's outcome. Materials and Methods: This is a cross-sectional study conducted over one year in the allied hospitals of Rawalpindi Medical University (RMU). Our sample size was 380 preoperative patients, who were selected by convenience sampling. The Amsterdam Preoperative Anxiety and Information Scale (APAIS) was used.Results: The overall prevalence of anxiety was 30.5%, while the prevalence of information requirement was 33.2%. The mean total APAIS was 12.73±8.56, the mean anxiety subscore was 8.25±5.58, and the mean need for information subscore was 4.48±3.16. A statistically significant difference was found in the scores of the patients based on age, gender, education, type of anesthesia, and type of surgery (p< 0.05). The previous history of anesthesia and the presence of comorbidities did not bring a significant difference in the scores of the patients (p>0.05). Postoperative pain was the most important concern, found in 32% of the patients.
Conclusion: Younger age group, female gender, having no formal education, surgery under regional anesthesia, and undergoing C-section, IOL implantation and septoplasty are associated with higher preoperative anxiety, while the presence of comorbidities and previous history of anesthesia are factors that do not significantly affect preoperative anxiety in our population.
Association of Lipid Profile with Non-Alcoholic Fatty Liver Disease diagnosed on Ultrasound
Authors: Zahoor Ambreen , Iqbal Iram ` , Naseem Sajid , Choudhary Zaidan Idrees 
Published: January 2021

Objectives: To evaluate lipid profile parameters in patients with various grades of non-alcoholic fatty liver disease (NAFLD) diagnosed on sonography.
Material and Method: This descriptive cross-sectional study was conducted at HBS General Hospital, Islamabad over a period of six months from January 2018 to June 2018. Seventy-nine adults of either gender diagnosed with NAFLD on ultrasonography were consecutively included. Fasting blood sample of all the subjects was analyzed for total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) Comparison of lipid abnormalities between different grades of NAFLD was done by statistical analysis with p-value <0.05 considered statistically significant.
Results: Out of the total 79 patients, grade I, II, and III NAFLD was diagnosed in 56.6%, 45.5%, and 3.9% respectively. Total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C) were raised in 28 (35.4%), 43 (54.4%) and 43 (54.4%) patients respectively. Low serum high-density lipoprotein cholesterol (HDL-C) levels were seen in 74 (93.6%) of patients. Statistical analysis showed a significant increase in frequency as well as mean values in all serum lipid profile parameters with the severity of NAFLD grades except total cholesterol (TC).
Conclusion: Increasing grades of NAFLD showed a significant correlation with higher levels of cholesterol, LDL, and decreasing levels of HDL, which are all associated with cardiovascular problems.
Comparing efficacy of Rifaximin plus Lactulose vs. Lactulose alone in treating Hepatic Encephalopathy
Authors: Hussain Tanveer , Sattar Misbah , Mustafa Sara , Batool Uzma , Iqbal Shafqat , Hassan Binish 
Published: January 2021

Background: Hepatic Encephalopathy is a syndrome observed in patients with liver cirrhosis. Various treatment modalities are in use for treatment of Porto Systemic Encephalopathy (PSE). Our study aimed to compare the efficacy of Rifaximin plus Lactulose vs.Lactulose alone in treating Hepatic Encephalopathy in local population.
Materials & Methods: The study was conducted at a tertiary care hospital recruiting decompensated chronic liver disease(DCLD) patients with PSE. Using simple random sampling, patients were divided in two groups (A & B). Patients in group A received Lactulose plus Rifaximin while group B received Lactulose alone. Efficacy of treatment was assessed as return of the conscious level to pre-encephalopathy state as per clinical examination within 1 week after start of the treatment.
Results: A total of 124 patients were included in the study with each group (A & B) containing 62 patients. Frequency and percentage of efficacy among group A (Rifaximin plus Lactulose) verses group B (Lactulose alone) in treating Hepatic encephalopathy was 45 (72.6%) and 32 (51.6%) respectively.
Conclusion: The study concluded that there is a significant difference in proportions of patients showing complete recovery from Hepatic encephalopathy treated with Lactulose plus Rifaximin as compared to Lactulose alone.
A Comparison of QTc Abnormalities in Cirrhotics with Non-Cirrohotic
Authors: Ali M Mujtaba , Quddus M Abdul , Shahzad Arslan , Khan M Fareed , Anwar Sheikh Taqqi , Raja Kapeel 
Published: January 2021

Objective: To compare the frequency of prolonged QTc interval in cirrhotics with non-cirrhotics having chronic liver disease.
Study design: Cohort study
Place and Duration of study: Department of Gastroenterology AK CMH/Sheikh Khalifa Bin Zayed Al Nahyan Hospital Rawalakot Azad Kashmir. Six months; (27-03-2019 to 26-09-2019)
Materials and Methods: One hundred patients with liver cirrhosis (group I) and 100 non-cirrhotic patients ((group II) had 12 lead ECG. QT interval was calculated. And the patients were evaluated for presence of prolonged QT interval. Statistical significant determined by chi-square test (p< 0.05 was taken as significant).
Results: The mean QTc duration in Group I was 0.536 + 0.012 seconds and group II was 0.431 + 0.015 seconds (p < 0.05). Prolonged QTc interval was present among 36(36%) patients in Group I and in 6 (6%) patients in Group II. (p < 0.05).
Conclusion: Our study findings revealed that cirrhotic patients have more chances of developing the QTc abnormalities as compared to the patients without the presence of cirrhotic liver.
Assessing the Efficacy of Pipelle Sampling as Outpatient Diagnostic Test in a Tertiary Care Hospital-Rawalpindi, 2020
Authors: Noor Nusrat , Anwar Rabiah , Akbar Rabia , Sadaf Ghazala , Yaqub Khan M 
Published: January 2021

ABSTRACT
Objective:
To assess the effectiveness and enlist clinical factors, which may affect effectiveness of Pipelle sampling in diagnosing endometrial pathology in patients with abnormal uterine bleeding and Post-menopausal Bleeding.
Study Design:
‘Analytical Cross-Sectional’ study.
Place and duration:
Gynecology Department at Combined Military Hospital Rawalpindi, in collaboration with Histo-Pathology Department, of six months duration i.e. from 1st December 2019 to 31st May 2020.
Patients and methods:
100 female patients of outpatient department with presenting complaints of either abnormal or post-menopausal bleeding were included in the study in the specified time frame. After informed written consent, Pipelle endometrial sampling was done on outpatient basis, and by consecutive sampling technique using lottery method, sample was sent for histopathological evaluation. Evaluated factors studied were: indications for the procedure, age, parity, age of menarche.
Results:
Of the total patients evaluated, 91% (n=100) were non-malignant, while 4% (n=100) were malignant. Inadequate tissue was obtained in 5% samples. Most common histopathological findings among reproductive age group were Proliferative and Secretory phase endometrium 64% (n=100). While in Post-menopausal age group 4% (n=100) were Endometrial carcinoma on histopathology. Inadequate tissue samples 5% (n=100) were noted among the Post-menopausal group. 6% samples showed endometrial hyperplasia. Pipelle Endometrial Sampling had sensitivity and specificity, in diagnosing the endometrial pathologies is summarized in Table 3.
Conclusion:
Pipelle Endometrial Sampling is an effective, safe, simple and acceptable procedure for diagnosing endometrial pathology. It is cost effective requiring no anesthesia with high sensitivity and specificity for detecting endometrial pathology.
Topiramate and Pregabalin in Lumbar Radicular Pain. Is Topiramate a better option?
Authors: Ishfaq Asim , Ashraf Javaria , Haider Aimen 
Published: January 2021

Abstract
Objective: To compare the efficacy of two anticonvulsant drugs topiramate and pregabalin on lumbar radicular pain and to find out whether topiramate is a better option or not.
Study design: Experimental study.
Place and Duration: Department of Neurosurgery, Combined Military Hospital Lahore. January 2020 - March 2020.
Patients and Methods: 60 patients of both gender divided in two groups of 30 each were included. Patients were assessed based on subjective impairment scale of oswestry disability index. Maximum score was calculated in percentage with higher score pointing to greater disability. Both drugs were given in low starting once daily dose, 75 mg for pregabalin and 25 mg for topiramate for two weeks followed by twice daily dose for two more weeks in patients not getting pain relief.
Results: Male to female ratio of 4:1 in both groups. Age range of 27-77 years (41.5+12.45) for pregabalin and 22-74 years (41.6+14.6) for topiramate group. Baseline demographics and pre drug pain measurement index were identical amongst two groups. Oswestry disability index was 49.2+18.3 pre drug and post drug 41+16.4 for pregabalin (p<0.01). For topiramate it was 43.6+37.9 pre drug and 37.9+17.3 post drug (p <0.01).
Conclusion: Both pregabalin and topiramate are effective in radicular pain management, and topiramate is not better but still a viable option as an alternative to pregabalin.
Comparison of Paricalcitol (I.V) and Alfacalcidol (I.V) in Treatment of Secondary Hyperparathyroidism (SHPT) in Hemodialysis Patients
Authors: Qaisar Mansoor Abbas , Abideen Zain Ul , Chattah Fateh Sher , Nadeem Muhammad , Hafeez Zahid 
Published: January 2021

ABSTRACT

Objective of study: To Compare the efficacy of Alfacalcidol (I.V) and Paricalcitol (I.V) for the treatment of secondary hyperparathyroidism (SHPT) in hemodialysis patients.
Materials and Methods: An open-label randomized clinical trial carried out to compare the efficacy of intravenous paricalcitol and alfacalcidol. We recruited 80 patients with end stage renal disease receiving maintenance hemodialysis in a tertiary care hospital dialysis unit. The participants were randomly divided into two groups. A wash out period of one week was decided for each patient in which he/she did not receive any medication for treatment of hypocalcemia, hyperphosphatemia or secondary hyperparathyroidism. Afterwards, patients received expanding dosage of alfacalcidol or paricalcitol for a time of about four months and then after a further wash out period of one week, each group received opposite treatment (paricalcitol or alfacalcidol) for further four months (16 weeks).
Results: The analyzed data for the same end points revealed no difference between the two groups. No significant statistical difference in terms of calcium levels in both groups was noted. The study also found no big difference in the ability of both drugs to treat secondary hyperparathyroidism, while keeping serum phosphate and calcium levels inside the desired range. The study also found no distinction in the frequency of hypercalcemia and hyperphosphatemia as a side effect of Vitamin D analogue’s treatment.

Conclusion: The study concludes that alfacalcidol and paricalcitol are equally effective in treatment of secondary hyperparathyroidism in dialysis population. Since Paricalcitol is expensive as compared to alfacalcidol, in an economically challenged country like Pakistan, Alfacalcidol can be a better choice when treating SHPT as we did not find any gross difference in the ability of two drugs to restrict SHPT.

Keywords: Alfacalcidol, Paricalcitol, Secondary hyperparathyroidism, Hemodialysis.
Antidiabetic Effects of Aloe Vera Whole Leaf Extract and Sitagliptin in Streptozotocin-induced Diabetic Rats
Authors: Javaid Sobia , Waheed Akbar 
Published: January 2021

Introduction: Aloe Vera, a perennial herb, is being used since ancient times for the cure of various diseases and is recently being used in curing diabetes due to the synergistic activity of its over 75 biologically active ingredients. The objective of the study was to compare the antidiabetic effects of Aloe Vera whole leaf extract with standard antidiabetic drug Sitagliptin on streptozotocin-induced diabetic rats.
Material and Methods: The present study was RCT, conducted at the Department of Pharmacology, Islamic International Medical College, Rawalpindi in collaboration with the National Institute of Health, Islamabad, Pakistan, from September 2019 to August 2020. A total of 40, young Sprague Dawley rats weighing between 220-250 grams were taken and randomly divided into Group A (Normal Control) and group B. After induction of Type-2 Diabetes, group B was further subdivided into 3 groups with 10 rats each: Group B1 (Diabetic Control), Group B2 (Aloe Vera whole Leaf Extract treated), GROUP B3 (Sitagliptin treated). Terminal Sampling was done to measure FBS and HbA1c on Day 60. Statistical Analysis was done by applying SPSS version 25. A one-way ANOVA test was used for assessing any difference in the mean values. Post-hoc Turkey analysis was conducted to compare any inter-group mean differences. P-value of <0.05 was considered significant.
Results: On completion of the study, at Day 60, mean FBS values for Rats in Group A were 82.40 mg/dl, for Group B1 498.40 mg/dl, for Group B2 89.30 mg/dl, and Group B3 93.00 mg/dl respectively. Mean HbA1c results for rats after terminal sampling in Group A were 3.71%, Group B1 11.84%, Group B2 4.02%, B3 3.73%. Rats in each of Group B2 (Aloe Vera whole leaf treated) and Group B3 (Sitagliptin treated) had a significant reduction in fasting blood sugar and HbA1c levels in comparison to Group B1 (diabetic control), with no statistically significant intergroup differences in results of Group A, Group B2 and Group B3.
Conclusion: Aloe Vera whole leaf extract significantly decreased fasting blood glucose and HbA1c levels with almost similar efficacy to Sitagliptin in diabetic rats.
Microdebrider-Assisted Turbinoplasty and Submucosal Diathermy for Inferior Turbinate Hypertrophy: A Randomized Clinical Trial
Authors: Arshad Muhammad , Ashfaq Ahmed Hasan , Rasheed Muhammad Tayyab , Khawaja Mahwash , Langove Muhammad Nadeem , Khan Muhammad Sheharyar 
Published: January 2021

ABSTRACT
Background: Nasal obstruction is a common presenting problem which can lead to symptoms like sleep disturbances, mouth breathing, oral cavity dryness. Hypertrophied inferior turbinate is a common cause of nasal obstruction. Microdebrider assisted turbinoplasty and submucosal diathermy are widely used methods for patients who fail to respond to medical therapy to relieve obstruction. The aim of the study was to compare two methods in terms of relief of nasal obstruction, reduction in sneezing and post-operative complications.
Material & Methods: This randomized clinical trial was conducted at ENT Department, Benazir Bhutto Hospital Rawalpindi, Pakistan for one year from 01-03-2018 to 28-02-2019. One hundred and twenty patients were randomized to into either MAT and SMD groups each with 60 patients. Nasal obstruction symptom evaluation score system (NOSE) was used to access relieve from obstruction and sneezing. SPSS 22, online chai square and fisher exact test calculators were used to analyze the data.
Results:
Two groups were comparable for age and gender. After 3 months of treatment, all patients in MAT group and 51 patients in SMD group were completely relieved from obstruction. At two weeks follow up 37(61.57%) patients in MAT group had grade 0 obstruction compared with 14 (23.33%) in SMD group and this difference was significant (p value .000). at one month follow up 55 (91.67%) patients in MAT while 46 (76.67%) had completely relieved obstruction and this difference was significant ( p value .024). Not all patients showed reduction in sneezing in both groups. 37 patients in MAT and 25 patients in SMD group had completely relieved from sneezing at third month follow up with MAT group showing significantly more patients with sneezing reduced at one month follow up. Crust formation was most seen complication in both groups, more with SMD group at two weeks follow up which responded to treatment alkaline nasal douches and crust removal.

Conclusion:
MAT gives better in terms of nasal obstruction relieved, reduction in sneezing and less complications than SMD procedure.
KEYWORDS: Microdebrider; Diathermy; Turbinates; Nasal obstruction