bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alcohol use among sexual minority women: Methods used and lessons learned in the 20-Year Chicago Health and Life Experiences of Women Study
Authors: Hughes Tonda , Wilsnack Sharon , Martin Kelly , Matthews Alicia , Johnson Timothy 
Published: June 2021

Background: Two decades ago, there was almost no research on alcohol use among sexual minority women (SMW, e.g., lesbian, bisexual). Since then, a growing body of scientific literature documents substantial sexual orientation-related disparities in alcohol use and alcohol-related problems. Research has identified multiple risk factors associated with high-risk/hazardous drinking among SMW. However, this research has almost exclusively used cross-sectional designs, limiting the ability to draw conclusions about processes through which sexual minority status affects alcohol use. Longitudinal designs, although very rare in research on alcohol use among SMW, are important for testing mediational mechanisms and necessary to understanding how changes in social determinants impact alcohol use.
Aim: To describe the processes and lessons learned in conducting a 20-year longitudinal study focused on alcohol use among SMW.
Methods: The Chicago Health and Life Experiences of Women (CHLEW) study includes five waves of data collection (2000–present) with an age and racially/ethnically diverse sample of 815 SMW (ages 18–83) originally recruited in the Chicago Metropolitan Area in Illinois, a midwestern state in the United States (U.S.). Measures and focus have evolved over the course of the study.
Results: The CHLEW study is the longest-running and most comprehensive study of SMW’s drinking in the U.S. or elsewhere. Findings reported in more than 50 published manuscripts have contributed to understanding variations in SMW’s risk for hazardous/harmful drinking based on sexual identity, age, race/ethnicity, sex/gender of partner, and many other factors.
Conclusions: By describing the process used in conducting this long-term study, its major findings, and the lessons learned, we hope to encourage and support other researchers in conducting longitudinal research focused on SMW’s health. Such research is critically important in understanding and ultimately eliminating sexual orientation-related health disparities.
‘Hydro‐point’ – The forgotten and unspoken entity in hydropneumothorax
Authors: Mahalingam Sasikumar , Rajendran Gunaseelan , Nathan Balamurugan , Kugan Ezhil , Sadasivam Anuusha 
Published: June 2021

AbstractEffusive pneumothorax is an abnormal collection of air and fluid within the pleural space: blood, pus, or serous fluid. Thus, effusive pneumothorax can be categorized as hemopneumothorax, pyopneumothorax, or hydropneumothorax, depending on the type of fluid accumulation. Hydropneumothorax is a clinical condition defined by the presence of air and serous fluid within the pleura space. Hydropneumothorax is one of the common respiratory emergencies encountered in the emergency department in India. Etiologies can be classified into infectious and non‐infectious causes, among which tuberculosis being the most common one. Point of care ultrasound (POCUS) can help diagnose hydropneumothorax at the bedside rather than shift the patient for an X‐ray. Here, we describe a case of hydropneumothorax, which was diagnosed using POCUS by characteristic sonographic signs, namely “Hydro‐point” and “barcode‐hydro point‐sinusoidal sign.” Sonographic hydro‐point is the transition zone of the air‐fluid interface, which is seen in hydropneumothorax. Targhetta et al., in 1992, introduced the term “Hydro‐point” in lung ultrasound for diagnosing hydropneumothorax but has been under‐reported/unspoken much in the literature. With the use of POCUS, we diagnosed and stabilized the patient in the Emergency Department.
Normalization in tumor ecosystem: Opportunities and challenges
Authors: Mortezaee Keywan 
Published: June 2021

AbstractCurrent research in cancer therapy aims to exploit efficient strategies to have long‐lasting effects on tumors and to reduce or even revoke the chance of recurrence. Within the tumor stroma, O2 and nutrients are abnormally distributed between various cells (preferentially for supplying cancer cells), the immune contexture is abnormally positioned (permissive essentially for cells exhibiting tumor‐promoting capacity), the fibroblast and fibrotic content is abnormally distributed (presence of both extracellular matrix [ECM] stiffening and ECM‐degrading factors both for tumor‐promoting purposes), and the tumor vasculature is abnormally orchestrated (for hindering drug delivery and increasing the chance of tumor metastasis). Resistance is actually an adaptive response to an imbalance in the tumor ecosystem; thus, the key consideration for effective cancer therapy is to bring back the normal status in this ecosystem so as to reach the desired durable outcome. Vascular normalization, metabolic modulation (glucose delivery in particular), balancing cellular dispersion, and balancing the pH rate and O2 delivery within the tumor microenvironment are suggested strategies to reverse abnormality within the tumor stroma.
Female and male Eurasian lynx have distinct spatial tactics at different life‐history stages in a high‐density population
Authors: Mengüllüoğlu Deniz , Edwards Sarah , Hofer Heribert , Berger Anne 
Published: June 2021

AbstractKnowledge regarding the spatial behavior of the Eurasian lynx is mainly inferred from populations in Europe. We used GPS telemetry to record the spatial behavior of nine individuals in northwestern Anatolia obtaining eleven home ranges (HRs). Analyses revealed the smallest mean HR sizes (nHR♀ = 4) at 57 km2 (95% kernel utilization distribution, KUD) and 56 km2 (95% minimum convex polygon, MCP), ever reported for adult female Eurasian lynx. Adult males either occupied small permanent territories (nHR♂.T = 2), with a mean of 176 km2 (95% KUD) and 150 km2 (95% MCP), or were residents without territories (floaters, nHR♂.F = 2) roaming across large, stable HRs with a mean size of 2,419 km2 (95% KUD) and 1,888 km2 (95% MCP), comparable to HR sizes of Scandinavian lynx populations. Three disperser subadult males did not hold stable HRs (mean 95% KUD = 203 km2, mean 95% MCP = 272 km2). At 4.9 individuals per 100 km2, population density was one of the highest recorded, suggesting that the presence of adult male floaters was a consequence of a landscape fully occupied by territorials and revealing a flexibility of spatial behavior of Eurasian lynx not previously recognized. Such a high population density, small HRs, and behavioral flexibility may have been aided by the legal protection from and apparent low levels of poaching of this population. The observed spatial tactics are unlikely to be seen in most of the previously studied Eurasian lynx populations, as they either suffer medium to high levels of human‐caused mortality or were unlikely to be at carrying capacity. For effective and appropriate conservation planning, data from felid populations in a reasonably natural state such as ours, where space, density, prey, and pathogens are likely to be the key drivers of spatial dynamics, are therefore essential.
Copper‐Catalyzed Aerobic Oxidation of N‐Pyridylindole Leading to Fused Quinazolinones
Authors: Ye Yaqing , Yue Yuanyuan , Guo Xiaohui , Chao Junli , Yang Yan , Sun Chunying , Lv Qingzhang , Liu Jianming 
Published: June 2021

AbstractCopper catalyzed aerobic oxidation enables the tandem selective and efficient transformation of N‐pyridylindole for the construction of 11H‐pyrido[2,1‐b]quinazolin‐11‐ones. The reaction shows good efficiency to accomplish the aerobic oxidation. Mechanistic investigation indicated the facile oxidation of N‐pyridylindole underwent the single‐electron‐transfer oxidation, the capture of molecular oxygen and the extrusion of carbon monoxide to deliver the desired 11H‐pyrido[2,1‐b]quinazolin‐11‐ones.
The value of interdisciplinary treatment for sickness absence in chronic pain: A nationwide register‐based cohort study
Authors: LoMartire Riccardo , Björk Mathilda , Dahlström Örjan , Constan Lea , Frumento Paolo , Vixner Linda , Gerdle Björn , Äng Björn O. 
Published: June 2021

AbstractBackgroundInterdisciplinary treatment (IDT) is an internationally recommended intervention for chronic pain, despite inconclusive evidence of its effects on sickness absence.MethodsWith data from 25,613 patients in Swedish specialist healthcare, we compared sickness absence, in the form of both sick leave and disability pensions, over a 5‐year period between patients either allocated to an IDT programme or to other/no interventions (controls). To obtain population‐average estimates, a Markov multistate model with theory‐based inverse probability weights was used to compute both the proportion of patients on sickness absence and the total sickness absence duration.ResultsIDT patients were more likely than controls to receive sickness absence benefits at any given time (baseline: 49% vs. 46%; 5‐year follow‐up: 36% vs. 35%), and thereby also had a higher total duration, with a mean (95% CI) of 67 (87, 48) more days than controls over the 5‐year period. Intriguingly, sick leave was higher in IDT patients (563 [552, 573] vs. 478 [466, 490] days), whereas disability pension was higher in controls (152 [144, 160] vs. 169 [161, 178] days).ConclusionAlthough sickness absence decreased over the study period in both IDT patients and controls, we found no support for IDT decreasing sickness absence more than other/no interventions in chronic pain patients.SignificanceIn this large study of chronic pain patients in specialist healthcare, sickness absence is compared over a 5‐year period between patients in an interdisciplinary treatment programme and other/no interventions. Sickness absence decreased over the study period in bothgroups; however, there was no support forthat it decreased more with interdisciplinary treatment than alternative interventions.
A Novel Carbon Nitride Nanosheets‐based Electrochemical Sensor for Determination of Hydroxychloroquine in Pharmaceutical Formulation and Synthetic Urine Samples
Authors: de Oliveira S. Silva Jonatas , Sant'Anna Mércia V. S. , Gevaerd Ava , Lima Jéssica B. S. , Monteiro Michael D. S. , Carvalho Sanny W. M. M. , Midori Sussuchi Eliana 
Published: June 2021

AbstractThis study introduces modified carbon paste electrodes with carbon nitride nanosheets (CNNS) and outlines their application for the determination of hydroxychloroquine sulfate (HCQ) in tablets and synthetic urine samples. CNNS were synthesized by hydrothermal route (200 °C, 10 h) using melamine and citric acid as their precursors. The carbon nitride nanosheets‐based electrode (CNNS/E) presented a linear dynamic range for HCQ (LDR), ranging from 10.0 nmol l−1 to 6.92 μmol l−1, and detection (LOD) and quantification limits (LOQ) of 0.16 nmol l−1 and 0.52 nmol l−1, respectively. LOD and LOQ were calculated by the equations: LOD=3(Sd/b), and LOQ=10(Sd/b). The modified sensor presented excellent relative standard deviations for parameters such as repeatability (2.39 % and 1.87 %) and reproducibility (3.22 % and 2.32 %) in HCQ oxidation peaks (1 and 2). The CNNS/E has not shown significant variations in its anodic signal intensity in the presence of some organic and inorganic substances. It is worth bearing in mind that CNNS/E can be easily manufactured and the sensor has the lowest HCQ detection limits reported so far. The proposed sensor was successfully applied for HCQ determination in tablets and synthetic urine, showing good recovery values and an error of 0.60 % about comparative method in tablet samples, assuring the quality of the method.
Interfacial adsorption–insertion mechanism induced by phase boundary toward better aqueous Zn‐ion battery
Authors: Shan Lutong , Wang Yiren , Liang Shuquan , Tang Boya , Yang Yongqiang , Wang Ziqing , Lu Bingan , Zhou Jiang 
Published: June 2021

AbstractBiphasic and multiphasic compounds have been well clarified to achieve extraordinary electrochemical properties as advanced energy storage materials. Yet the role of phase boundaries in improving the performance is remained to be illustrated. Herein, we reported the biphasic vanadate, that is, Na1.2V3O8/K2V6O16·1.5H2O (designated as Na0.5K0.5VO), and detected the novel interfacial adsorption–insertion mechanism induced by phase boundaries. First‐principles calculations indicated that large amount of Zn2+ and H+ ions would be absorbed by the phase boundaries and most of them would insert into the host structure, which not only promote the specific capacity, but also effectively reduce diffusion energy barrier toward faster reaction kinetics. Driven by this advanced interfacial adsorption–insertion mechanism, the aqueous Zn/Na0.5K0.5VO is able to perform excellent rate capability as well as long‐term cycling performance. A stable capacity of 267 mA h g−1 after 800 cycles at 5 A g−1 can be achieved. The discovery of this mechanism is beneficial to understand the performance enhancement mechanism of biphasic and multiphasic compounds as well as pave pathway for the strategic design of high‐performance energy storage materials.image
The European Big Data Value Ecosystem
Authors: Curry Edward , Metzger Andreas , Zillner Sonja , Pazzaglia Jean-Christophe , García Robles Ana , Hahn Thomas , Le Bars Laure , Petkovic Milan , De Lama Nuria 
Published: June 2021

AbstractThe adoption of big data technology within industrial sectors facilitates organizations to gain competitive advantage. The impacts of big data go beyond the commercial world, creating significant societal impact, from improving healthcare systems to the energy-efficient operation of cities and transportation infrastructure, to increasing the transparency and efficiency of public administration. In order to exploit the potential of big data to create value for society, citizens and businesses, Europe needs to embrace new technology, applications, use cases and business models within and across various sectors and domains. In the early part of the 2010s, a clear strategy centring around the notion of the European Big Data Value Ecosystem started to take form with the aim of increasing the competitiveness of European industries through a data ecosystem which tackles the fundamental elements of big data value, including the ecosystem, research and innovation, business, policy and regulation, and the emerging elements of data-driven AI and common European data spaces. This chapter describes the big data value ecosystem and its strategic importance. It details the challenges of creating this ecosystem and outlines the vision and strategy of the Big Data Value Public-Private Partnership and the Big Data Value Association, which together formed the core of the ecosystem, to make Europe the world leader in the creation of big data value. Finally, it details the elements of big data value which were addressed to realise this vision.
Risk Factors for Cerebral Aneurysm Rupture in Mongolia
Authors: Bechstein Matthias , Gansukh Amarjargal , Regzengombo Boldbat , Byambajav Oyun , Meyer Lukas , Schönfeld Michael , Kniep Helge , Hanning Uta , Broocks Gabriel , Gansukh Tserenchunt , Fiehler Jens 
Published: June 2021

Abstract
Purpose
Identification of country-specific demographic, medical, lifestyle, and geoenvironmental risk factors for cerebral aneurysm rupture in the developing Asian country of Mongolia. First-time estimation of the crude national incidence of aneurysmal subarachnoid hemorrhage (aSAH).

Methods
A retrospective analysis of all intracranial digital subtraction angiographies (DSA) acquired in Mongolia during the 2‑year period 2016–2017 (1714 examinations) was performed. During this period, DSA was used as primary diagnostic imaging modality for acute severe neurological symptoms in the sole hospital nationwide dedicated to neurological patients. The catchment area of the hospital included the whole country. Patients with incidental and ruptured aneurysms were reviewed with respect to their medical history and living conditions. The data was used to install a Mongolian aneurysm registry.

Results
The estimated annual crude incidence of cerebral aneurysm rupture was 6.71 for the country of Mongolia and 14.53 per 100,000 persons for the capital region of Ulaanbaatar. Risk factors common in developed countries also applied for the Mongolian population: A medical history of hypertension, smoking or the presence of multiple aneurysms led to a higher relative risk of rupture. In contrast, female gender was not associated with a higher risk in this national cohort. Males pursuing a traditional nomadic living may exhibit a specifically high risk of rupture.

Conclusion
Disease management of over 200 individuals/year with aSAH constitutes a socioeconomic burden in Mongolia. Efforts to raise awareness of the risk factors hypertension and smoking among the Mongolian population are desirable. Measures to improve the nationwide availability of modern neurovascular treatment options are currently under consideration.
Selected dried fruits as a source of nutrients
Authors: Rybicka Iga , Kiewlicz Justyna , Kowalczewski Przemysław Łukasz , Gliszczyńska-Świgło Anna 
Published: June 2021

AbstractDried fruits are an excellent alternative to unhealthy snacks. Twelve commercially available dried fruits were selected: dates, raisins, prunes, Goji berry, chokeberry, rose hip, sea buckthorn, berberis, physalis, haritaki, noni and juniper. The nutritional value in terms of moisture, ash, protein, fat, carbohydrate, dietary fiber, energy value, mineral composition, antioxidant activity and tannins was compared. It is a novelty in the literature in relation to the particular analytes (e.g., minerals, tannins) and/or fruits (e.g., berberis, noni, haritaki). Especially rich in protein were Goji berry (13.3%), sea buckthorn (9.3%), noni (8.9%) and physalis (8.0%); in fat − sea buckthorn (11.2%); in dietary fiber (4.4–53.0%) − most of analyzed products. High antioxidant capacity was noticed for haritaki, berberis, rose hip, Goji berry, and physalis. An important source of minerals was 100 g of: noni (345 mg of Ca; 251 mg of Mg), rose hip (844 mg of Ca; 207 mg of Mg), juniper (564 mg of Ca), sea buckthorn (58 mg of Fe), berberis (24 mg of Fe) and haritaki (14 mg of Fe). The nutritionally attractive dried fruits have the potential for wider application in food formulations.
A DNA-based method for distinction of fly artifacts from human bloodstains
Authors: Bini Carla , Giorgetti Arianna , Iuvaro Alessandra , Giovannini Elena , Gianfreda Denise , Pelletti Guido , Pelotti Susi 
Published: June 2021

AbstractFly artifacts resulting from insect activity could act as confounding factors on a crime scene and interfere with bloodstain pattern analysis interpretation. Several techniques have been proposed to distinguish fly artifacts from human bloodstains based on morphological approach and immunological assay, but a DNA-based method has not been developed so far. Even if in forensic genetic investigations the detection of human DNA is generally the primary goal, fly artifacts can provide useful information on the dynamics of crime events. The present study provides a molecular method to detect fly DNA from artifacts deposited by Calliphora vomitoria after feeding on human blood through the analysis of the mitochondrial cytochrome oxidase gene subunit I (COI). Fly artifacts originated from digestive process and of different morphology spanning from red and brownish/light brown, circular and elliptical stains to artifacts with sperm-like tail or a tear-shaped body were collected. The COI amplification was successfully obtained in 94% of fly artifact samples. The method showed high sensitivity and reproducibility, and no human DNA contamination was observed, offering specificity for use in confirmatory test. This molecular approach permits the distinction of fly artifacts from genuine bloodstains and the identification of fly’s species through the COI region sequencing by protocols usually applied in forensic genetic laboratories.
Resistance of the Montgomery Ladder Against Simple SCA: Theory and Practice
Authors: Kabin Ievgen , Dyka Zoya , Klann Dan , Aftowicz Marcin , Langendoerfer Peter 
Published: June 2021

AbstractThe Montgomery kP algorithm i.e. the Montgomery ladder is reported in literature as resistant against simple SCA due to the fact that the processing of each key bit value of the scalar k is done using the same sequence of operations. We implemented the Montgomery kP algorithm using Lopez-Dahab projective coordinates for the NIST elliptic curve B-233. We instantiated the same VHDL code for a wide range of clock frequencies for the same target FPGA and using the same compiler options. We measured electromagnetic traces of the kP executions using the same input data, i.e. scalar k and elliptic curve point P, and measurement setup. Additionally, we synthesized the same VHDL code for two IHP CMOS technologies, for a broad spectrum of frequencies. We simulated the power consumption of each synthesized design during an execution of the kP operation, always using the same scalar k and elliptic curve point P as inputs. Our experiments clearly show that the success of simple electromagnetic analysis attacks against FPGA implementations as well as the one of simple power analysis attacks against synthesized ASIC designs depends on the target frequency for which the design was implemented and at which it is executed significantly. In our experiments the scalar k was successfully revealed via simple visual inspection of the electromagnetic traces of the FPGA for frequencies from 40 to 100 MHz when standard compile options were used as well as from 50 MHz up to 240 MHz when performance optimizing compile options were used. We obtained similar results attacking the power traces simulated for the ASIC. Despite the significant differences of the here investigated technologies the designs’ resistance against the attacks performed is similar: only a few points in the traces represent strong leakage sources allowing to reveal the key at very low and very high frequencies. For the “middle” frequencies the number of points which allow to successfully reveal the key increases when increasing the frequency.
Urteilsbildung
Authors: Wolff Stephan 
Published: June 2021

ZusammenfassungAus einer ethnomethodologischen Perspektive werden einige grundlegende Aspekte der Urteilsbildung in sozialen Diensten vorgestellt, sowie Medien, Orte und Technologien angesprochen, die damals wie heute, zum Teil freilich mit anderen Akzenten, die Urteilsbildung in der Sozialen Arbeit prägen.
Sozial bewegt
Authors: Haase Katrin 
Published: June 2021

ZusammenfassungDie spezialisierte Opferberatung hat sich aus antifaschistischen und antirassistischen Initiativen entwickelt. Mit der Geschichte des Beratungsfeldes wird auf das gesellschaftskritische Potenzial Sozialer Arbeit hingewiesen und die Notwendigkeit des Erinnerns herausgestellt.
Why feeling competent matters
Authors: Raven Hanna , Pels Fabian 
Published: June 2021

AbstractPhysical education is an important setting for the promotion of personal resources of children and adolescents. One of the main personal resources in education in general and physical education in particular is self-efficacy. The current study investigated the association between physical education-related self-efficacy and basic psychological need satisfaction according to Self-Determination Theory in adolescent students. A total of 708 students from grades nine to eleven were surveyed using questionnaires. The results of a linear regression analysis indicated that there is a relationship between the need for competence satisfaction and physical education-related self-efficacy (R2corr = 0.29, p < 0.001, f2 = 0.40), while the need for autonomy and the need for relatedness were not related to self-efficacy. One possible interpretation is that the feeling of being competent in physical education enables the development of positive self-efficacy. As practical implications, the implementation of assessment systems in physical education is recommended, focusing on students’ individual performance to positively influence competence satisfaction and, subsequently, self-efficacy.