bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risks of and From SARS-CoV-2 Infection and COVID-19 in People With Diabetes: A Systematic Review of Reviews
Authors: Hartmann-Boyce Jamie , Rees Karen , Perring James C. , Kerneis Sven A. , Morris Elizabeth M. , Goyder Clare , Otunla Afolarin A. , James Olivia E. , Syam Nandana R. , Seidu Samuel , Khunti Kamlesh 
Published: October 2021

BACKGROUND
This review was commissioned by the World Health Organization and presents a summary of the latest research evidence on the impact of coronavirus disease 2019 (COVID-19) on people with diabetes (PWD).

PURPOSE
To review the evidence regarding the extent to which PWD are at increased risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and/or of suffering its complications, including associated mortality.

DATA SOURCES
We searched the Cochrane COVID-19 Study Register, Embase, MEDLINE, and LitCOVID on 3 December 2020.

STUDY SELECTION
Systematic reviews synthesizing data on PWD exposed to SARS-CoV-2 infection, reporting data on confirmed SARS-CoV-2 infection, admission to hospital and/or to intensive care unit (ICU) with COVID-19, and death with COVID-19 were used.

DATA EXTRACTION
One reviewer appraised and extracted data; data were checked by a second.

DATA SYNTHESIS
Data from 112 systematic reviews were narratively synthesized and displayed using effect direction plots. Reviews provided consistent evidence that diabetes is a risk factor for severe disease and death from COVID-19. Fewer data were available on ICU admission, but where available, these data also signaled increased risk. Within PWD, higher blood glucose levels both prior to and during COVID-19 illness were associated with worse COVID-19 outcomes. Type 1 diabetes was associated with worse outcomes than type 2 diabetes. There were no appropriate data for discerning whether diabetes was a risk factor for acquiring SARS-CoV-2 infection.

LIMITATIONS
Due to the nature of the review questions, the majority of data contributing to included reviews come from retrospective observational studies. Reviews varied in the extent to which they assessed risk of bias.

CONCLUSIONS
There are no data on whether diabetes predisposes to infection with SARS-CoV-2. Data consistently show that diabetes increases risk of severe COVID-19. As both diabetes and worse COVID-19 outcomes are associated with socioeconomic disadvantage, their intersection warrants particular attention.
Prediction of Personal Glycemic Responses to Food for Individuals With Type 1 Diabetes Through Integration of Clinical and Microbial Data
Authors: Shilo Smadar , Godneva Anastasia , Rachmiel Marianna , Korem Tal , Kolobkov Dmitry , Karady Tal , Bar Noam , Wolf Bat Chen , Glantz-Gashai Yitav , Cohen Michal , Zuckerman Levin Nehama , Shehadeh Naim , Gruber Noah , Levran Neriya , Koren Shlomit , Weinberger Adina , Pinhas-Hamiel Orit , Segal Eran 
Published: October 2021

OBJECTIVE
Despite technological advances, results from various clinical trials have repeatedly shown that many individuals with type 1 diabetes (T1D) do not achieve their glycemic goals. One of the major challenges in disease management is the administration of an accurate amount of insulin for each meal that will match the expected postprandial glycemic response (PPGR). The objective of this study was to develop a prediction model for PPGR in individuals with T1D.

RESEARCH DESIGN AND METHODS
We recruited individuals with T1D who were using continuous glucose monitoring and continuous subcutaneous insulin infusion devices simultaneously to a prospective cohort and profiled them for 2 weeks. Participants were asked to report real-time dietary intake using a designated mobile app. We measured their PPGRs and devised machine learning algorithms for PPGR prediction, which integrate glucose measurements, insulin dosages, dietary habits, blood parameters, anthropometrics, exercise, and gut microbiota. Data of the PPGR of 900 healthy individuals to 41,371 meals were also integrated into the model. The performance of the models was evaluated with 10-fold cross validation.

RESULTS
A total of 121 individuals with T1D, 75 adults and 46 children, were included in the study. PPGR to 6,377 meals was measured. Our PPGR prediction model substantially outperforms a baseline model with emulation of standard of care (correlation of R = 0.59 compared with R = 0.40 for predicted and observed PPGR respectively; P &lt; 10−10). The model was robust across different subpopulations. Feature attribution analysis revealed that glucose levels at meal initiation, glucose trend 30 min prior to meal, meal carbohydrate content, and meal’s carbohydrate-to-fat ratio were the most influential features for the model.

CONCLUSIONS
Our model enables a more accurate prediction of PPGR and therefore may allow a better adjustment of the required insulin dosage for meals. It can be further implemented in closed loop systems and may lead to rationally designed nutritional interventions personally tailored for individuals with T1D on the basis of meals with expected low glycemic response.
IMPLEMENTASI ETNOMATIKA BERBASIS PERMAINAN TRADISIONAL TERHADAP BERPIKIR KRITIS DENGAN KOVARIABEL KEMAMPUAN VERBAL SISWA KELAS II SD
Authors: Made Alit Darmawan  , Sariyasa  , I Made Gunamantha  
Published: October 2021

Saat ini pembelajaran berbasis budaya tidak selalu diterapkan dalam kurikulum sekolah, termasuk pada kegiatan belajar mengajar di sekolah. Salah satu bentuk pembelajaran berbasis budaya adalah etnomatematika. Budaya permainan tradisional curik-curik tanpa disadari dapat diterapkan pada konsep matematika, khususnya materi waktu. Tujuan penelitian adalah untuk mengetahui pengaruh implementasi pendekatan pembelajaran Etnomatematika berbasis permainan tradisional curik-curik terhadap kemampuan berpikir kritis siswa ditinjau dari kemampuan verbal siswa kelas II SD di Gugus Pattimura Kecamatan Denpasar Selatan. Data dianalisis menggunakan ANAKOVA dengan bantuan SPSS 21.0 for windows. Sebanyak 63 siswa kelas II dipilih sebagai sampel dengan teknik random sampling. Data yang dikumpulkan adalah data kemampuan berpikir kritis dengan tes essai dan kemampuan verbal siswa dengan tes pilihan ganda. Hasil penelitian menunjukan bahwa: pertama, terdapat perbedaan yang signifikan terhadap kemampuan berpikir kritis siswa antara siswa yang menerapkan pendekatan etnomatematika dan siswa yang mengikuti model pembelajaran konvensional ( Fhitung = 7,071 > Ftabel = 3,998). Kedua, setelah dikendalikan oleh kovariabel kemampuan verbal, terdapat perbedaan yang signifikan antara kemampuan berpikir kritis siswa yang mengikuti pendekatan pembelajaran etnomatematika dan siswa yang mengikuti model pembelajaran konvensional (Fhitung = 4,295 > Ftabel = 4,00). Ketiga, terdapat kontribusi kovariabel kemampuan verbal yang signifikan terhadap kemampuan berpikir kritis siswa (rhitung = 0,570 > rtabel =0,215).
Transtorno do espectro autista
Authors: Oliveira Letícia Dal Picolo Dal Secco de , Garcia Rafael Vilas Boas , Menotti Ana Rubia Saes , Donadeli Josiane Maria , Aran Marineide Aquino de Souza , Carmo João dos Santos 
Published: October 2021

Dentre as dificuldades encontradas para a inclusão de crianças com Transtorno do Espectro Autista (TEA) nas escolas está a falta de conhecimentos técnicos e instrumentos específicos que ofereçam suporte à prática dos profissionais da educação e às escolas. Considerando essa necessidade, foi aplicado um programa de capacitação, com base no referencial teórico da Análise do Comportamento, para 18 professores do Ensino Fundamental de uma escola de cidade do interior do Estado de São Paulo, com o objetivo de capacitá-los a aprenderem estratégias para promover a participação de alunos com TEA em atividades de grupo utilizando jogos cooperativos. Foram ministradas cinco aulas com enfoque prático, abordando os temas: jogos cooperativos, prompt e reforço. A avaliação do curso foi feita de três modos: aplicação de Pré-Teste, Pós Teste e Follow-up. Para avaliar a aprendizagem dos professores participantes, foi solicitada aos professores uma atividade de simulação de situações e intervenções vivenciadas junto a alunos com TEA, a partir dos conteúdos aprendidos, e a aplicação da Escala de Avaliação do Ensino em Língua Oral em Contexto Escolar (EVALOE) para avaliar a atuação dos ministrantes. Os resultados indicaram que os participantes apresentaram mais acertos no pós-teste do que no pré-teste, a avaliação deles sobre o curso foi positiva e a atuação dos ministrantes satisfatória. Ressalta-se a importância de elaborar capacitações para os docentes e a necessidade de fornecer a eles mais materiais de apoio e atividades de autoaprendizagem.
Gaivoron—Zavallia section of the Middle Pobuzhzhіa is the most representative part of the granulite complex of the Ukrainian Shield (structural-tectonophysical results and magnetometric studies)
Authors: Мychak S.V. , Bakarzhieva М.І. , Marchenko A.V. , Reshetnyk M.M. , Farfuliak L.V. , Оrlyuk M.I. , Gintov О.B. 
Published: October 2021

In the article according to the geological and geophysical data of the well-exposed areas of development of Archean rocks of the Ukrainian Shield, two alternative approaches to establishing the structure and stratigraphy of the oldest granulite complexes are discuss. The outcrops of the enderbite-gneiss complex up to 3.6—3.8 billion years old are located along the Southern Bug River between the Gaivoron town and the Zavallia village.
The first, «stratigenic-metamorphogenic» approach assumes that the main features of the composition and structure of the Lower Archean complexes are inherited from the original stratotypic strata. These strata are transformed in the conditions of quasi-isochemical metamorphism with preservation of the sequence of formation in section and the primary constitution in the form of stratification, rhythmicity, direction of change of their composition vertically and laterally. On the structural-formation map and geological section of the Gaivoron—Zavallia section, the Archean granulite complex is shown in the form of a synclinorium composed of four adjacent formations, which are equated to the world of metamorphosed volcanic-sedimentary rocks.
The second, «deformation-metamorphogenic» approach, which is supported by the authors of this article, is based on the idea that the granulite complex of Pobuzhzhіa is a subvertically layered medium formed by tangential tectonic forces. The latter lead to shear deformations and displacement of matter at the atomic-molecular (with mineral transformation of rocks) and rock masses at the regional level. This creates structural and textural elements that are superimposed on the primary structure of rocks and often erase it.
Field structural-tectonophysical, tectonofacial and magnetometric studies, its results are presented in the article. It was performed specifically to compare these two concepts. Magnetometric studies have shown that the enderbite-gneiss complex of the district by its magnetic characteristics belongs to the middle and lower crust of the Ukrainian Shield.
Features of the national development of possibilities forensic diagnostics of the gunshot injuries
Authors: Zmiievska Yuliia , Savka Ivan 
Published: October 2021

This article shows the role and contribution of individual forensic scientists and famous forensic academies in the development of learning gunshot injuries. The article presents an analysis of the national literary sources concerning development of possibilities and methods of forensic diagnostics of the main traumatic factor of gunshot injuries. The role of up-to-date digital technologies, particularly the method of three-dimensional spatial reconstruction of the gunshot wounds, which can empower possibilities of forensic diagnostics of the main traumatic factor of gunshot injuries are shown.
Aim of the work. To analyze the development of diagnostic methods of a kind of the main traumatic factor of gunshot injuries in forensic medicine, to find the up-to-date and most diagnostically valuable methods for further investigation and implementation into experts’ practical work.
Conclusions. Analysis of national forensic experts’ studies shows that forensic medical examination of gunshot body wounds has always been of current interest and become more and more actual. In every period of forensic medicine development new instrumental and laboratory methods of examination of gunshot wounds have appeared. One of the most topical and promising methods are means of the three-dimensional spatial reconstruction. It can improve the possibilities of forensic medical diagnostics of a kind and characteristic of the main traumatic factor of gunshot wounds.
Establishment of accurate criteria for diagnosis of the time since death in forensic medical practice
Authors: Savka Ivan , Kozan Natalia , Dunaiev Oleksandr , Oliynyk Igor 
Published: October 2021

Over the course of technological development, it is recommended to use more and more new modern methods to assess the time since death. However, most of them have practical limitations or show insufficient results that could ensure the most accurate assessment of the time since death in forensic medical practice.
Aim of the work. To review modern scientific articles on the problem of establishing the time since death, to identify the most promising areas of work that can potentially be used in the daily work of practitioners.
Conclusions. The analysis of scientific literature shows the relevance of the search and development of new modern methods of assessment of time since death, which could provide scientific validity, specificity and objectivity of the expert opinion.
Differential diagnostics of the presence of damage by the method of digital polarization mapping of microsocopy images of hystological sections of human organs
Authors: Litvinenko Oleksandra , Vanchulyak Oleh , Soltys Irina , Mikhailova Olga , Motrich Artem 
Published: October 2021

The article presents the results of experimental testing of methods of azimuthal-invariant polarization mapping of microscopic images of samples of histological sections of the myocardium and lung tissue; time monitoring of changes in the magnitude of statistical moments of the 1-4th orders, characterizing the distributions of the azimuth and ellipticity of polarization of microscopic images of myocardial and lung tissue samples with different age of damage; determination of the diagnostic efficiency (time interval and accuracy) of establishing the age of damage to human internal organs by digital histological methods of mapping azimuth maps and polarization ellipticity of microscopic images.
Aim of the work. Development of a digital histology technique for samples of human internal organs.
Materials and methods. The object of the study was the histology of samples of human internal organs (myocardium, lung tissue) with different duration of damage from 1 hour to 120 hours. For control, we used BT samples from those who died from coronary artery disease with different duration of damage from 1 hour to 120 hours. The studies were carried out using the method of digital polarization mapping of microscopic images of histological sections of biological tissues of human internal organs.
Results. Revealed the following ranges ramp variation quantity statistics polarizing digital histology and accuracy of the limitation of damage: a. Arts azimuth polarization microscopic image of a magnification ×40 (asymmetry – 12 hours, kurtosis – 12 hours, accuracy – 55-60 min), maps of ellipticity of polarization of microscopic images with a magnification of ×40 (asymmetry – 12 hours, kurtosis – 12 hours, accuracy – 65-75 min).
Conclusions. Scenarios of changes in the statistical structure of maps of azimuth and ellipticity of polarization of microscopic images of histological sections of human internal organs have been determined - with an increase in the duration of damage, the value of the mean and variance decreases, the asymmetry and kurtosis increase.
Bioelectrical Phase Angle, Muscle Damage Markers and Inflammatory Response After a Competitive Match in Professional Soccer Players
Authors: Moya-Amaya Heliodoro , Molina-López Antonio , Berralaguilar Antonio Jesús , Rojano-Ortega Daniel , La Rosa Carlos Javier Berral-De , La Rosa Francisco José Berral-De 
Published: October 2021

Abstract

Introduction. The purposes of this study were 1) to evaluate changes from baseline levels in bioelectrical phase angle (PhA) and markers of muscle damage and inflammation in professional players 36 h after a soccer match, and 2) to analyze the relationships between PhA and markers of muscle damage and inflammation in order to investigate if PhA might be a useful parameter to monitor recovery.

Material and methods. Eighteen male professional soccer players participated in this study. Plasma lactate dehydrogenase (LDH) and creatine kinase (CK) activities, plasma C-reactive protein (CRP) and interleukin-6 (IL-6) concentrations, and PhA were measured before and 36 h after a competitive match.

Results. Changes in LDH and CK 36 h after the match were greater than their reference change values (RCV). Changes in CRP and IL-6 were, however, lower than their corresponding RCV. 36 h after the match, significant correlations were observed between PhA and LDH (r = 0.714, p = 0.001), PhA and CK (r = 0.787, p = 0.000), and PhA and CRP (r = 0.554, p = 0.017).

Conclusions. Although IL-6 and CRP have been traditionally analyzed together to monitor inflammation after intense exercise, since 36 h after the match they have already returned or started to return to baseline levels, the use of them alone is not a good option to monitor inflammation throughout recovery. PhA might be used as a predictor of muscle damage and inflammation, but further studies covering the whole recovery period are warranted.
APLIKASI POLYMERASE CHAIN REACTION (PCR) KONVENSIONAL DAN REAL TIME- PCR UNTUK DETEKSI VIRUS VNN (Viral Nervous Necrosis) PADA IKAN KERAPU MACAN (Epinephelus fuscoguttatus)
Authors: Kurniawati Made Devi , Sumaryam Sumaryam , Hayati Nurul 
Published: October 2021

VNN ( Viral Nervous Necrosis ) adalah jenis virus nodaviridae yang menyerang ikan kerapu macan (Epinephelus fuscoguttatus), terutama pada fase larva dan benih sehingga dapat menyebabkan kematian massal. Pengujian penyakit virus yang paling sering digunakan adalah pengujian dengan metode PCR Konvensional dan Real Time-PCR. Tujuan dari penelitian ini adalah untuk mengetahui metode manakah yang paling tepat dalam mendeteksi virus VNN pada ikan kerapu macan di Balai KIPM Denpasar, Bali. Dari keseluruhan ikan yang di identifikasi VNN pada ikan kerapu macan yang menunjukan jumlah prevalensi yang hampir sama antara menggunakan identifikasi dengan metode uji PCR Konvensional sebesar 10,30% dan dengan uji Real Time PCR sebesar 10 % yang menunjukan bahwa kedua metode tersebut sama-sama bisa digunakan sebagai metode untuk uji virus VNN, tetapi metode PCR Konvensional membutuhkan waktu lebih lama (waktu pengujian 5 jam) dibandingkan metode Real Time-PCR (waktu pengujian 2,5 jam). Kata Kunci : Viral Necrosis Nerveus (VNN) , PCR Konvensional, Real Time PCR, (Epinephelus fuscoguttatus)
PERSEPSI MASYARAKAT TERHADAP NILAI EKONOMIS IKAN TERBANG (cypselurus sp.) DAN MOTIVASINYA DALAM PENGEMBANGAN USAHA PERIKANAN DI KABUPATEN MALUKU TENGGARA
Authors: Pical Venda Jolanda , Leasa Samuel Filemon Imanuel 
Published: October 2021

Ikan terbang (cypselurus sp.) di Maluku Tenggara sangat potensial tetapi yang dimanfaatkan hanya telurnya sedangkan ikan terbang belum dimanfaatkan secara optimal. Tujuan penelitian adalah menganalisis persepsi masyarakat terhadap nilai ekonomi ikan terbang (cypselurus sp.) dan motivasinya dalam pengembangan usaha perikanan di Kabupaten Maluku Tenggara. Lokasi penelitian adalah di Tual Kabupaten Maluku Tenggara. Metode sampling menggunakan stratified random sampling. Data primer melalui kuesioner, FGD, wawancara mendalam, dokumentasi, catatan harian serta observasi. Data sekunder dari penelusuran pustaka. Hasil penelitian tentang identitas dan karakteristik responden mayoritasnya berada di usia produktif, didominasi laki-laki dan sudah menikah. Responden mayoritas berpendidikan SMU, kurang mengikuti pendidikan non formal. Responden terlibat dalam usaha perikanan namun tidak terlibat dalam usaha non perikanan. Selain itu juga tidak terlibat dalam organisasi masyarakat, pekerjaan utamanya adalah nelayan dan tidak memiliki pekerjaan sampingan. Persepsi masyarakat terhadap nilai ekonomi ikan terbang (cypselurus sp.) adalah rendah. Hal ini disebabkan nilai jualnya dalam bentuk segar maupun olahan sangat rendah dibandingkan ikan pelagis lainnya. Motivasi masyarakat dalam pengembangan usaha perikanan ikan terbang (cypselurus sp.) sangat tinggi dilihat dari tingkat partisipasi masyarakat dalam mengikuti kegiatan penyuluhan dan pelatihan optimalisasi pemanfaatan ikan terbang (cypselurus sp.) bagi pengembangan usaha perikanan berskala industri rumah tangga sangat tinggi.
Mobile-Assisted Language Learning (MALL) in English language acquisition: a critical literature review
Authors: Gael Kristianus Erwin , Elmiana Dewi Satria 
Published: October 2021

The objective of this study is ‘how effective mobile apps in learning English?’ by exploring the use of mobile apps in English as a Second Language (ESL)/English as a Foreign Language (EFL) acquisition. It examines how employing MALL in learning English can improve students’ receptive skills, productive skills, and other skills by conducting critical literature review to answer the research question. The results showed that employing mobile applications in learning English is effective to develop L2 learners’ English skills and also Mobile apps help L2 learners in learning English both as the second and foreign language. Interestingly, in the situation of the global pandemic which many schools are closed, mobile technology has helped students in learning English skills. It can be suggested that by employing Mobile Assisted Language Learning (MALL) in learning English skills plays a crucial role in the situation of the global pandemic of COVID 19 where teachers and students can use mobile apps both in and outside the classroom because it is convenient and user friendly.
CRIMINAL LIABILITY FOR CRIMES IN THE SPHERE OF MEDICAL ACTIVITIES: TOPICAL ISSUES OF DEVELOPMENT OF LEGISLATION AND LAW ENFORCEMENT PRACTICE
Authors: Дронова Юлия Анатольевна 
Published: October 2021

В статье рассматриваются актуальные вопросы квалификации и расследования ятрогенных преступлений на основе материалов судебной практики, а также обозначена проблема отсутствия единообразного подхода к уголовно-правовой оценке случаев фальсификации вакцинации от коронавируса, совершенной медицинскими работниками.
The article discusses topical issues of qualification and investigation of iatrogenic crimes based on materials of judicial practice, and also outlines the problem of the lack of a uniform approach to the criminal legal assessment of cases of falsification of vaccination against coronavirus committed by medical workers.