bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Breath of Fresh Air: Approaches to Environmental Health in Late Medieval Urban Communities
Authors: Rawcliffe Carole 
Published: October 2021

AbstractThis essay explores the medieval belief that disease was spread by the foul odours arising from such common nuisances as butchers’ waste, dung heaps, stagnant water, and tanneries, as a result of which great importance was placed upon fresh, clean air in medieval cities, especially in times of pestilence. It examines the medical rationale behind these ideas, which derived from Classical Greece and reflect sophisticated assumptions about human physiology. It also considers the numerous sanitary measures that were introduced at both a national and local level in pursuit of a hygienic urban environment, and the extent to which ordinary citizens recognised the vital role played by the air that they breathed in preserving or endangering communal health.
‘Let Lovers Sigh Out the Rest’: Witnessing the Breath in the Early Modern Emotional Body
Authors: Tsentourou Naya 
Published: October 2021

AbstractThis essay examines how breath is observed, recorded, and accounted for in cases of love melancholy in early modern literary and medical texts. It draws on the poetry of George Herbert and the works of Robert Burton and Jacques Ferrand on lovesickness to argue that writing on the respiration of the melancholic lover in the Renaissance involves a process of performative displacement as well as entanglement, most visible in the practice of intertextuality. As Tsentourou shows, intertextual references to emotional breathing blur the binary between patient and physician, casting bodies and texts as spaces where the detached witness conspires with the lovesick subject, and, in turn, with the reader.
Ecological Indicators for Surface Water Quality - Methodological Approaches to Fish Community Assessments in China and Germany
Authors: Beggel Sebastian , Pander Joachim , Geist Jürgen 
Published: October 2021

AbstractAssessments of aquatic ecosystem health rely increasingly on biological indicators such as fish community structure, but national approaches differ. To use bioindicators efficiently and to allow cross-country comparisons, standardized tools and methods are required. Within this study, currently applied procedures for stream ecosystem assessment in China and Germany are summarized and active and passive fish sampling methodologies used in both countries are investigated. The methodological comparison was based on the results of a joint Chinese German workshops within the SINOWATER project in 2016. A joint sampling campaign was then conducted in 2017 at 6 representative sites within 70 km of the Fan River, a tributary to the Liao River System in Liaoning province, China. Active methods comprised single-pass electrofishing methods as typically applied in Germany and China as well as seining. As passive methods, common minnow traps, gill-netting and longline-fishing were used. To allow the comparability between methods, a standardized sampling design comprising several replicates at each site was chosen, covering a range of different ecological stream conditions. By comparison of the different fishing methodologies, electrofishing yielded the best overall results to assess fish biodiversity in terms of species abundance, richness and catch per unit effort. Differences in the effectiveness of the different electrofishing approaches mostly depended on the power source used. To cover the full spectrum of the fish community and to detect very rare species, a combination of different active and passive methods was most useful. If electrofishing is the method of choice, it is very important to adjust the gear power to river specific conditions such as flow, size and depth. The results of this joint Chinese-German study may aid in the selection of suitable sampling methods for fish community assessments in the future.
Dianchi Shallow Lake Management
Authors: Rankenhohn Florian , Strauß Tido , Wermter Paul 
Published: October 2021

AbstractLake Dianchi in the Chinese province Yunnan is a shallow lake suffering from algae blooms for years due to high pollution. We conducted a thorough survey of the water quality of the northern part of the lake called Caohai. This study was intended as the basis for the system understanding of the shallow lake of Caohai. The study consisted of two steps. First we collected available environmental, hydrological and pollution data from Kunming authorities and other sources. It was possible to parameterise a lake model model based on the preliminary data set. It supported first estimations of management scenarios. But the first and quick answers came with a relevant vagueness. Relevant monitoring data was still missing like P release from lake-internal sediment.Because data uncertainty causes model uncertainty and model uncertainty causes planning and management uncertainties, we recommended and conducted a thorough sediment and river pollution monitoring campaign in 2017. Examination of the sediment phosphorus release and additional measurements of N and P was crucial for the improvement of the shallow lake model of Caohai. In May 2018 we presented and discussed the results of StoLaM shallow lake model of Caohai and the outcomes of a set of management scenarios.The StoLaM shallow lake model for Caohai used in SINOWATER indicates that sediment dredging could contribute to the control of algae by limitation of phosphorus, but sediment management can only produce sustainable effects when the overall nutrient input and especially the phosphorus input from the inflows will be reduced significantly.
Mobile Edge Computing for the Internet of Vehicles
Authors: Zhang Yan 
Published: October 2021

AbstractThe advancement of cyber physical information has led to the pervasive use of smart vehicles while enabling various types of powerful mobile applications, which usually require high-intensity processing under strict delay constraints. Given their limited on-board computing capabilities, smart vehicles can offload these processing tasks to edge servers for execution. However, a highly dynamic topology, a complex vehicular communication environment, and edge node heterogeneity pose significant challenges in vehicular edge computing management. To address these challenges, in this chapter we investigate the characteristics of edge computing from both the application and service perspectives and introduce a hierarchical edge computing framework. Moreover, we leverage artificial intelligence technology to propose efficient task offloading and resource scheduling schemes.
Mobile Edge Computing for UAVs
Authors: Zhang Yan 
Published: October 2021

AbstractThis chapter studies mobile edge computing (MEC) networks assisted by unmanned aerial vehicles (UAVs). According to the application scenarios, we consider three roles for UAVs in MEC networks: exploiting MEC computing capabilities, serving as a computing server, and serving as a relay for computation offloading. Furthermore, the details for resource allocation and optimization are presented in the three scenarios of UAV-assisted MEC networks. In addition, we focus on the situation in which a UAV not only functions as an MEC server to inspect turbines on a wind farm, but also performs task computation. To facilitate wide applications of UAV-assisted MEC in practice, this chapter highlights the main implementation issues of UAV-assisted MEC, including optimal UAV deployment, wind models, and joint trajectory–computation performance optimization.
The importance of kinematic twists and genuine saturation effects in dijet production at the Electron-Ion Collider
Authors: Boussarie Renaud , Mäntysaari Heikki , Salazar Farid , Schenke Björn 
Published: October 2021

Abstract
We compute the differential yield for quark anti-quark dijet production in high-energy electron-proton and electron-nucleus collisions at small x as a function of the relative momentum P⊥ and momentum imbalance k⊥ of the dijet system for different photon virtualities Q2, and study the elliptic and quadrangular anisotropies in the relative angle between P⊥ and k⊥. We review and extend the analysis in [1], which compared the results of the Color Glass Condensate (CGC) with those obtained using the transverse momentum dependent (TMD) framework. In particular, we include in our comparison the improved TMD (ITMD) framework, which resums kinematic power corrections of the ratio k⊥ over the hard scale Q⊥. By comparing ITMD and CGC results we are able to isolate genuine higher saturation contributions in the ratio Qs/Q⊥ which are resummed only in the CGC. These saturation contributions are in addition to those in the Weizsäcker-Williams gluon TMD that appear in powers of Qs/k⊥. We provide numerical estimates of these contributions for inclusive dijet production at the future Electron-Ion Collider, and identify kinematic windows where they can become relevant in the measurement of dijet and dihadron azimuthal correlations. We argue that such measurements will allow the detailed experimental study of both kinematic power corrections and genuine gluon saturation effects.
Semidual Kitaev lattice model and tensor network representation
Authors: Girelli Florian , Osei Prince K. , Osumanu Abdulmajid 
Published: October 2021

Abstract
Kitaev’s lattice models are usually defined as representations of the Drinfeld quantum double D(H) = H ⋈ H*op, as an example of a double cross product quantum group. We propose a new version based instead on M(H) = Hcop ⧑ H as an example of Majid’s bicrossproduct quantum group, related by semidualisation or ‘quantum Born reciprocity’ to D(H). Given a finite-dimensional Hopf algebra H, we show that a quadrangulated oriented surface defines a representation of the bicrossproduct quantum group Hcop ⧑ H. Even though the bicrossproduct has a more complicated and entangled coproduct, the construction of this new model is relatively natural as it relies on the use of the covariant Hopf algebra actions. Working locally, we obtain an exactly solvable Hamiltonian for the model and provide a definition of the ground state in terms of a tensor network representation.
Monitoring process-related impurities in biologics–host cell protein analysis
Authors: Pilely Katrine , Johansen Martin Rask , Lund Rikke Raaen , Kofoed Thomas , Jørgensen Thomas Kjærsgaard , Skriver Lars , Mørtz Ejvind 
Published: October 2021

AbstractDuring biologics development, manufacturers must demonstrate clearance of host cell impurities and contaminants to ensure drug purity, manufacturing process consistency, and patient safety. Host cell proteins (HCPs) are a major class of process-related impurities and require monitoring and documentation of their presence through development and manufacturing. Even in residual amounts, they are known to affect product quality and efficacy as well as patient safety. HCP analysis using enzyme-linked immunosorbent assay (HCP-ELISA) is the standard technique, due to its simple handling, short analysis time, and high sensitivity for protein impurities. Liquid chromatography mass spectrometry (LC–MS) is an orthogonal method for HCP analysis and is increasingly included in regulatory documentation. LC–MS offers advantages where HCP-ELISA has drawbacks, e.g., the ability to identify and quantify individual HCPs. This article summarizes the available knowledge about monitoring HCPs in biologics and presents the newest trends in HCP analysis with current state-of-the-art HCP measurement tools. Through case studies, we present examples of HCP control strategies that have been used in regulatory license applications, using an MS-based coverage analysis and HCP-ELISA and LC–MS for HCP quantification. This provides novel insight into the rapid evolving strategy of HCP analysis. Improvements in technologies to evaluate HCP-ELISA suitability and the implementation of orthogonal LC–MS methods for HCP analysis are important to rationally manipulate, engineer, and select suitable cell lines and downstream processing steps to limit problematic HCPs.
Instability and Stasis Among the Microbiome of Seagrass Leaves, Roots and Rhizomes, and Nearby Sediments Within a Natural pH Gradient
Authors: Banister Raymond B. , Schwarz Melbert T. , Fine Maoz , Ritchie Kim B. , Muller Erinn M. 
Published: October 2021

AbstractSeagrass meadows are hotspots of biodiversity with considerable economic and ecological value. The health of seagrass ecosystems is influenced in part by the makeup and stability of their microbiome, but microbiome composition can be sensitive to environmental change such as nutrient availability, elevated temperatures, and reduced pH. The objective of the present study was to characterize the bacterial community of the leaves, bulk samples of roots and rhizomes, and proximal sediment of the seagrass species Cymodocea nodosa along the natural pH gradient of Levante Bay, Vulcano Island, Italy. The bacterial community was determined by characterizing the 16S rRNA amplicon sequencing and analyzing the operational taxonomic unit classification of bacterial DNA within samples. Statistical analyses were used to explore how life-long exposure to different pH/pCO2 conditions may be associated with significant differences in microbial communities, dominant bacterial classes, and microbial diversity within each plant section and sediment. The microbiome of C. nodosa significantly differed among all sample types and site-specific differences were detected within sediment and root/rhizome microbial communities, but not the leaves. These results show that C. nodosa leaves have a consistent microbial community even across a pH range of 8.15 to 6.05. The ability for C. nodosa to regulate and maintain microbial structure may indicate a semblance of resilience within these vital ecosystems under projected changes in environmental conditions such as ocean acidification.
Individual values and spirituality and their meaning for affective well-being and engagement with life in very old age
Authors: Reissmann Marcella , Storms Anna , Woopen Christiane 
Published: October 2021

Abstract
Background
Individuals’ ideals and aspirations are considered to constitute a central reference frame for subjective evaluations of their perceived reality, and, thus, to be crucial for individual quality of life (QoL) outcomes. By examining individual values and spirituality in very old people, the aim of this study was to describe two constructs representing the aspirations of the individual, as well as the relation of these constructs to both hedonic and eudaimonic QoL outcomes in very old age (VOA).

Material and methods
Cross-sectional data from a representative survey of people in VOA (NRW80+, n = 1863) were used. Individual values were assessed based on the Portrait Value Questionnaire. A revised questionnaire was developed drawing on the Spiritual Health and Life-Orientation Measure. Individual values and spirituality were studied using descriptive statistics, and hierarchical linear regression models were used to analyze their predictive value for two QoL outcomes: 1) affective well-being as an indicator of hedonic QoL, which was assessed using the positive affect subscale of the short form of the Positive and Negative Affect Schedule, and 2) engagement with life, which captures eudaimonic aspects and which was measured with a subscale of the Valuation of Life Scale.

Results
The most important values were both protection and growth-oriented values with a social focus. However, only values representing strivings for growth had a positive association with QoL outcomes. Spirituality was of high relevance to very old people, although not in the sense of religious institutions or practices. Rather, it predominantly consisted in environmental, interpersonal, and transcendental connectedness, all of which were positively connected to QoL outcomes.

Conclusion
Individual values and spirituality can be an important resource for hedonic as well as eudaimonic QoL; however, age-related losses may lead to an emphasis of protective values that are not beneficial in terms of QoL. To support older people on their spiritual journey, a broad concept of spirituality needs to be established among researchers as well as practitioners.
Fetal ciliopathies: a retrospective observational single-center study
Authors: Simonini Corinna , Floeck Anne , Strizek Brigitte , Mueller Andreas , Gembruch Ulrich , Geipel Annegret 
Published: October 2021

Abstract
Purpose
Report on the diagnosis of prenatally suspected multisystem ciliopathies in a single center between 2002 and 2020.

Methods
Retrospective observational single-center study including pregnancies with prenatal ultrasound features of multisystem ciliopathies, such as hyperechogenic kidneys together with polydactyly and/or other skeletal and extraskeletal findings. Cases were compared according to their prenatal findings and outcomes.

Results
36 cases of multisystem ciliopathies were diagnosed. Meckel-Gruber syndrome (MKS) was the most common ciliopathy (n = 19/36, 52.8%), followed by disorders that belong to the group of short-rib thoracic dysplasia (SRTD, n = 10/36, 27.8%) McKusick–Kaufmann syndrome (MKKS, n = 4/36, 11.1%), Bardet–Biedl syndrome (BBS, n = 2/36, 5.5%) and Joubert syndrome (n = 1/36, 2.8%). All cases showed abnormalities of the kidneys, most often hyperechogenic parenchyma (n = 26/36, 72.2%), cystic dysplasia (n = 24/36, 66.7%), and/or bilateral kidney enlargement (n = 22/36, 61.1%). Oligohydramnios was mainly present in fetuses with MKS. Polydactyly (n = 18/36), abnormalities of the CNS (n = 25/36), and heart defects (n = 10/36) were associated in 50%, 69.4%, and 27.8%, respectively.

Conclusion
Prenatal detection of renal abnormalities associated with skeletal or brain abnormalities should raise the suspicion for multisystem ciliopathies. Prenatal ultrasound can help to differentiate between different diseases and pave the way for subsequent targeted genetic testing.
Music perception and speech intelligibility in noise performance by Italian-speaking cochlear implant users
Authors: Dincer D’Alessandro Hilal , Boyle Patrick J. , Portanova Ginevra , Mancini Patrizia 
Published: October 2021

Abstract
Objective
The goal of this study was to investigate the performance correlations between music perception and speech intelligibility in noise by Italian-speaking cochlear implant (CI) users.

Materials and methods
Twenty postlingually deafened adults with unilateral CIs (mean age 65 years, range 46–92 years) were tested with a music quality questionnaire using three passages of music from Classical Music, Jazz, and Soul. Speech recognition in noise was assessed using two newly developed adaptive tests in Italian: The Sentence Test with Adaptive Randomized Roving levels (STARR) and Matrix tests.

Results
Median quality ratings for Classical, Jazz and Soul music were 63%, 58% and 58%, respectively. Median SRTs for the STARR and Matrix tests were 14.3 dB and 7.6 dB, respectively. STARR performance was significantly correlated with Classical music ratings (rs = − 0.49, p = 0.029), whereas Matrix performance was significantly correlated with both Classical (rs = − 0.48, p = 0.031) and Jazz music ratings (rs = − 0.56, p = 0.011).

Conclusion
Speech with competitive noise and music are naturally present in everyday listening environments. Recent speech perception tests based on an adaptive paradigm and sentence materials in relation with music quality measures might be representative of everyday performance in CI users. The present data contribute to cross-language studies and suggest that improving music perception in CI users may yield everyday benefit in speech perception in noise and may hence enhance the quality of listening for CI users.
Tympanal bone fracture in forensic practice
Authors: Evain France , Lovblad Karl-Olof , Fracasso Tony 
Published: October 2021

AbstractA tympanal bone fracture is an uncommon complication of head trauma and is mostly associated with a mandibular or petrous bone fracture. Upon reviewing the medicolegal literature, we could not find any publications on this topic. Tympanal bone fracture may lead to chronic complications (including external auditory canal stenosis and conductive hearing loss), with an important impact in both the medical and judiciary fields (e.g., chronic disabilities with loss of income). We decided to investigate the prevalence and mechanisms of tympanal bone fractures by means of a retrospective observational study on living victims who underwent head computed tomography after blunt head trauma and clinical forensic investigation at our center. We selected 159 cases of living victims with blunt head trauma (following an assault, traffic accident, or work accident) between January 2016 and December 2020. Re-examination of head imaging revealed 12 cases of tympanal bone fracture. Seven individuals showed cranial fractures involving the petrous bone (on the same side as the tympanal bone fracture). Three individuals had a temporomandibular fracture after a fall with chin impact. Only two victims exhibited an isolated tympanal bone fracture.
Surgery for chronic pancreatitis: the comparison of two high-volume centers reveals lack of a uniform operative management
Authors: Surci Niccolò , Bassi Claudio , Salvia Roberto , Marchegiani Giovanni , Casetti Luca , Deiro Giacomo , Bergmann Christina , Tamandl Dietmar , Schindl Martin , Mühlbacher Jakob , Sahora Klaus 
Published: October 2021

Abstract
Purpose
Many aspects of surgical therapy for chronic pancreatitis (CP), including the correct indication and timing, as well as the most appropriate operative techniques, are still a matter of debate in the surgical community and vary widely across different centers. The aim of the present study was to uncover and analyze these differences by comparing the experiences of two specialized surgical units in Italy and Austria.

Methods
All patients operated for CP between 2000 and 2018 at the two centers involved were included in this retrospective analysis. Data regarding the clinical history and the pre- and perioperative surgical course were analyzed and compared between the two institutions.

Results
Our analysis showed a progressive decrease in the annual rate of pancreatic surgical procedures performed for CP in Verona (no. = 91) over the last two decades (from 3% to less than 1%); by contrast, this percentage increased from 3 to 9% in Vienna (no. = 77) during the same time frame. Considerable differences were also detected with regard to the timing of surgery from the first diagnosis of CP — 4 years (IQR 5.5) in the Austrian series vs two (IQR 4.0) in the Italian series -, and of indications for surgery, with a 12% higher prevalence of groove pancreatitis among patients in the Verona cohort.

Conclusion
The comparison of the surgical attitude towards CP between two surgical centers proved that a consistent approach to this pathology still is lacking. The identification of common guidelines and labels of surgical eligibility is advisable in order to avoid interinstitutional treatment disparities.