bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular Characterization of Resistance-Nodulation-cell Division Efflux Pump Genes in Multidrug-Resistant Acinetobacter baumannii
Authors: Raza Shahid , Gautam Hitender , Mohapatra Sarita , Sood Seema , Dhawan Benu , Chaudhry Rama , Kapil Arti , Das Bimal Kumar 
Published: November 2021

Introduction:
Multidrug-resistant Acinetobacter baumannii is galloping, posing threat to tackle, and leaving us with limited options of treatment.

Methods:
The purpose of this study is to find the genotypic association in drug-resistant A. baumannii isolated from different sterile body fluids. Matrix-assisted laser desorption/ionization–time of flight confirmed A. baumannii isolates were taken and minimum inhibitory concentration (MIC) was determined by VITEK-2 AST system. The presence of resistance nodulation–division (RND)-efflux pump genes AdeABC-RS was detected by multiplex polymerase chain reaction.

Results:
Of the total 40 A. baumannii, 32 (80%) were multidrug resistant though all isolates were susceptible to Tigecycline. Similarly, 26 (81.25%) isolates were positive for RND-efflux pump genes AdeABC-RS.

Discussion:
RND efflux pump AdeABC-RS system plays a significant role in emerging multi drug resistant A. baumannii. Mutation in AdeS gene deciphers the role of regulatory gene. Hence, antimicrobial stewardship should be strictly followed and efflux pump inhibiting substances should be vigorously searched to bring back the era of existing antibiotics.
A Study of Performance of First MBBS Students in Internal Assessment Conducted Online During the COVID-19 Pandemic
Authors: Chaudhuri Arunima , Mondal Tanushree , Paul Suhrita , Goswami Ayan 
Published: November 2021

Background:
The COVID-19 pandemic has greatly impacted the progress of medical education. As the crisis continues, it is important to develop valid and reliable methods of assessment.

Aims:
To assess the impact of the competency-based medical education (CBME) implemented online in the department of physiology during this pandemic on the results of internal assessments conducted online.

Materials and Methods:
This pilot study was conducted on two hundred First-year MBBS students at Burdwan Medical College after taking Institutional clearance in 6 months. Two internal assessments had to be conducted online in 6 months. We divided our internal assessment sessions which were conducted at three monthly intervals into 4 compartments: multiple-choice questions, short answer type questions, orals, and spots. We conducted two surveys to assess the stress levels of the students and two feedback surveys to assess our teaching program. Statistical analysis: T-test and Chi-square test was used to analyze the data.

Results:
Assessments scores of students in the first session were 59.68 ± 10.91; assessment scores of students in the second session were 73.21 ± 8.66; P < 0.001 ** (highly significant). Perceived stress score (PSS) in the first survey was 21.36 ± 3.84 and PSS in the second survey was 20.77 ± 4.13; P = 0.144. Thirty students failed in the first session while 1 in the second session, χ
2 = 32.1; P < 0.0001**. At the end of 3 months, 11.4% had difficulty in studying physiology, while at the end of 6 months, 8.5% had difficulty in studying physiology with online support.

Conclusions:
The first MBBS students were able to cope up better with the online mode of teaching with the passage of time and regular feedback provided to them. The results of the present study demonstrate that the department of physiology could implement CBME online and conduct internal assessments also.
Espacios de verificación en TikTok. Comunicación y formas narrativas para combatir la desinformación
Authors: Sidorenko Bautista Pavel , Alonso López Nadia , Giacomelli Fabio 
Published: November 2021

Introducción. Desde 2020 TikTok se ha convertido en red social tendencia a escala global. De ser inicialmente una plataforma para adolescentes se ha convertido en un entorno digital donde impera la comunicación efímera muy estimulante y visual. Hoy confluyen en ella una amplia diversidad de emisores, entre los cuales asisten medios y periodista. Y como ocurre en toras redes sociales, en un contexto de hiperconectividad, las informaciones falsas se viralizan con facilidad, complejizando así el desarrollo de la desinformación. Metodologí­a. A partir de una triangulación de técnicas de carácter cualitativo y cuantitativo, tales como estudio de casos, análisis de contenidos, entrevistas a profundidad y encuestas, se analiza la comunicación de los fact-checkers con perfil activo en TikTok, con el fin de determinar las claves para desmentir bulos y luchar contra la desinformación en una red social tan particular, donde aparentemente los usuarios asisten para divertirse y distraerse. Discusión y conclusiones. Queda en evidencia no solo la pertinencia sino la necesidad de medios, periodistas y específicamente medios de verificación, de llevar a cabo su labor a través de nuevos escenarios como lo es TikTok, no solo para poder asegurar un incremento del alcance del mensaje de cara a nuevos segmentos de audiencia, sino como un proceso innovador para atacar el fenómeno de la desinformación, noticias falsas y especulaciones cada vez más descentralizado a través de los canales digitales. TikTok ha supuesto un reto narrativo a partir de la síntesis del mensaje y la creatividad visual.
EL JUEGO DE LOS ABALORIOS: del Último Teorema de Fermat a los Solitones Ópticos
Authors: Fujioka Jorge , Rodríguez Alfredo Gómez , Cerón Áurea Espinosa 
Published: November 2021

Siguiendo la idea del Juego de los Abalorios (de Hermann Hesse), en este trabajo investigamos qué relación existe entre el último Teorema de Fermat (UTF) y los solitones ópticos. Para encontrar esta relación examinamos los pasos principales que condujeron a la demostración del UTF, empezando por la conjetura de Taniyama-Shimura, y pasando por las contribuciones de Hellegouarch, Frey y Ribet, hasta llegar al trabajo de Wiles. Posteriormente examinamos algunas de las ecuaciones que describen a los solitones ópticos. De este análisis se desprende que las curvas elípticas constituyen el puente que relaciona ambos temas. Veremos, además, que las ecuaciones que describen solitones ópticos también podrían tener alguna relación con la criptografía. Finalmente veremos que los resultados encontrados en este trabajo nos permiten proponer 2 conjeturas que constituyen temas de investigación para el futuro.

Following the idea of the Glass Bead Game (by Hermann Hesse), in this work we investigate what relation exists between Fermat´s Last Theorem (FLT) and the optical solitons. To find such a relationship we examine the principal steps which lead to the demonstration of FLT, starting from Taniyama-Shimura´s conjecture, then paying attention to the contributions of Hellegouarch, Frey and Ribet, and finally the work of Wiles. Then we examine some of the equations which describe optical solitons. From this analysis it follows that the elliptic curves constitute the bridge that connects both topics. Moreover, we will observe that the equations which describe optical solitons might also be related to cryptography. Finally, we will see that the results found in this communication permit us to propose 2 conjectures that constitute research topics for future works.
Preliminary considerations on the local educational project (pel), an example from the huancavelica region (peru)
Authors: Bourguet Jose Yvan Vargas , Sánchez Raúl Eleazar Arias 
Published: November 2021

This article presents a general and normative overview of the Local Educational Project (PEL), its characteristics, structure, management and implementation as a local educational management instrument. In the same way, we point out some reflections in this regard and share a brief description of its development in the Huancavelica region (Peru).

El presente artículo presenta un panorama general y normativo sobre Proyecto Educativo Local (PEL), sus características, estructura, gestión y puesta en marcha como instrumento de gestión educativa local. De igual manera, señalamos algunas reflexiones al respecto y compartimos una breve descripción de su desarrollo en la región Huancavelica (Perú).
Circular Airport Concept Analysis for Indonesian Archipelago
Authors: Kusumalestari A S , Franciscus F 
Published: November 2021

Circular Airport Concept, issued by Hessellink in 2014, divides the expert opinion, but the project is still running. The idea is how visible to engage this concept into Indonesian Archipelago. To build airport within limit area for several islands in Indonesia is a big challenge. Some pioneer routes which connecting remote areas with a small aircraft is still searching for some development. Another challenge is the environmental sustainability. This paper makes an analysis about application of the concept into Indonesian Archipelago, and how this concept might be a solution. The discussion will cover analysis of airport design, aircraft to operate, and area to be treated.
PREVENÇÃO E CONTROLE DE INFECÇÃO NO SETOR DE TERAPIA RENAL SUBSTITUTIVA
Authors: Motta Raquel de Oliveira Laudiosa da , Azevedo Suely Lopes de , Oliveira Aline Silva da Fonte Santa Rosa de , Costa Mauriceia Ferreira Silva 
Published: November 2021

Objetivo: Identificar evidências nas publicações oficiais do Ministério da Saúde, ANVISA e demais bases de dados sobre ações preventivas e de controle de infecção nos serviços de hemodiálise. Método: Trata-se de uma revisão bibliográfica da literatura com busca de artigos nas bases de dados: MEDLINE, LILACS, BDENF e no portal SCIELO, bem como em documentos oficiais dos órgãos fiscalizadores e de controle, realizada de julho a setembro de 2021. Ao final do processo foram selecionados seis artigos que compuseram a amostra do estudo. Resultados e Discussão: Para responder ao objetivo desse estudo, na fase de interpretação dos estudos selecionados, foram evidenciadas e construídas duas categorias de análise que versam sobre a prevenção e o controle de infecção nos serviços de hemodiálise, a saber: “Prevenção e controle de infecção relacionado ao acesso vascular” e “Prevenção e controle de infecções na terapia renal substitutiva”. Considerações finais: Os estudos apontaram que a instalação de medidas de prevenção e controle, bem como realizar modificações necessárias nos processos de trabalho e também estruturais são de extrema relevância. Busca-se com isso a redução ou anulação da possibilidade de transmissão das infecções virais e bacterianas nos pacientes hemodialíticos. Sendo este o recurso fundamental para a promoção de uma assistência de qualidade nos serviços de hemodiálise.
Thermodynamic Probability Analysis of the Effects of Rb on the Corrosion Susceptibility of Cr-Containing Steels for Nuclear Materials Canisters
Authors: Wang Kang , Demarest Charles R. , Matthew Asmussen R. , Scully John R. , Zhou Bi-Cheng 
Published: November 2021

Rubidium (Rb) generated from the β-decay of Kr-85 has been theorized to be corrosive toward steel, specifically in the storage of Kr-85 nuclear waste streams. In the present study, the phase equilibria of RbxCryOz with Rb in dry oxygen and water are investigated to understand a possible pathway to unusual deterioration of the corrosion resistance of canister steels in the presence of Rb. It was found that, in dry oxygen environments, the accumulation of Rb (more than 0.01 mol) can completely consume the Cr in 1 mol of AISI 4130 steel by forming α-Rb2CrO4 and Rb3CrO4 and prevent the formation of protective Cr2O3 scale. In aqueous environments, RbxCryOz are metastable species. In order to investigate their role, the probability of forming various oxides is invoked in order to avoid the all-or-nothing approach to oxide formation typical of E-pH diagram, which only predicts the most stable species dissolved, ionized, or solid ionized. Thus, the probability of forming RbxCryOz was considered and reported herein. It was found RbxCryOz can possess a larger than 7% probability of forming over Cr2O3 in the Rb-rich case and 15% in the Cr-rich case, indicating that it is expected to find a small amount of RbxCryOz in the thermodynamically formed reaction products. Even though Cr2O3 is more stable than RbxCryOz, the protective Cr2O3 scale is likely to have some vulnerability to Rb, leading to one possible route for the decline in the corrosion resistance of steel canisters in aqueous environments. Therefore, from a thermodynamic perspective, the current study supports the hypothesis that Rb can thermodynamically react with Cr in steels and can lead to the formation of RbxCryOz at certain potentials and pH levels, showing the Rb influence of steel corrosion cannot be discounted. The paper considers experimental mixed potential and pH levels observed and their relationship to thermodynamic probability. From this relative corrosion resistance can be assessed in a preliminary way in aqueous environments.
Pembrolizumab (Keytruda)
Authors: Team Reimbursement 
Published: November 2021

CADTH recommends that Keytruda should be reimbursed by public drug plans for the treatment of adult and pediatric patients with refractory or relapsed classical Hodgkin lymphoma (cHL) if certain conditions are met.
Keytruda should only be reimbursed to treat patients who have failed autologous stem cell transplant (ASCT) or who are not candidates for multi-agent salvage chemotherapy and ASCT.
Keytruda should only be reimbursed as monotherapy and if the cost of pembrolizumab is reduced.
ESTRUTURA PRODUTIVA DA ECONOMIA BRASILEIRA E SETORES-CHAVE PARA O DESENVOLVIMENTO
Authors: Sesso Filho Umberto Antonio , Brene Paulo Rogério Alves , Rangel Ronaldo Raemy , Sesso Patrícia Pompermayer , Zapparoli Irene Domenes 
Published: November 2021

O objetivo do estudo foi identificar os setores-chave e motrizes para o desenvolvimento na economia brasileira com a utilização de três indicadores econômicos baseados na matriz de insumo-produto do Brasil do ano de 2017: índices de ligações intersetoriais de Rasmussen-Hirschman, índices GHS e campo de influência. O setor-chave é aquele com efeitos de encadeamento pela compra e venda de insumos acima da média da economia. O setor motriz, além de ser chave, possui relativa maior dimensão de seus efeitos de encadeamento e impulsos motores significativos sobre o crescimento da economia. A análise conjunta e complementar dos métodos de identificação de setores-chave e motrizes conduziram a uma lista de atividades econômicas que são capazes de estimular o sistema produtivo, os quais deveriam ser prioritários para investimentos para sua expansão para otimizar o uso de recursos públicos e privados. Os setores-chave identificados foram (10) Outros produtos alimentares, (19) Refino de petróleo, (38) Energia elétrica, gás e outras utilidades, (43) Transporte terrestre e (40) Construção. Os setores motrizes são (19), (38) e (40), pois além de possuírem os maiores impactos nas cadeias produtivas nas quais estão inseridos também têm alta participação em termos de produção nacional.Palavras-chave: insumo-produto, setores-chave, desenvolvimento econômico, cadeia produtiva.
Pengaruh Kualitas Layanan Internal dan Kepuasan Kerja terhadap Kinerja Karyawan Hotel
Authors: Jati Ni Luh Putu Surining , Surata I Ketut , Febrianto I Gusti Agung 
Published: November 2021

This research was conducted to analyze the influence of internal service quality on job performance, analyze the influence of job satisfaction on job performance, and analyze the influence of internal service quality and job satisfaction on job performance at The Ritz-Carlton Bali. Questionnaires as the data collection technique were distributed to employees at The Ritz-Carlton Bali as the respondents. The total samples were 85 respondents which identified using simple random sampling technique and Slovin formula as sampling technique. The measurements of this research used a Likert scale. The methods of data analysis used were classic assumption testing, coefficient determination, hypothesis test, and testing by SPSS version 24. The results of data analysis indicated that internal service quality has a positive and significant effect on job performance at The Ritz-Carlton Bali as proven by the value of tcount (3,259) > ttabel (1,663). Job satisfaction has a positive and significant effect on job performance at The Ritz-Carlton Bali as proven by the value of tcount 2,742 > ttabel (1,663). and Internal service quality and job satisfaction simultaneously have a contributing is 5,21% through to the job performance. While the other remaining 4,79% is influenced by the other variable studied in this research.
Pengetahuan, Ketersediaan Data dan Pengawasan Pimpinan Berhubungan Dengan Keakuratan Laporan Kesehatan Ibu Hamil Dari Puskesmas Ke Dinas Kesehatan Provinsi DKI Jakarta Tahun 2021
Authors: Haryanto Mia , Siswani Sri 
Published: November 2021

Keakuratan pelaksanaan sistem pencatatan dan pelaporan kesehatan Ibu Hamil dari Puskesmas ke Dinas Kesehatan Provinsi DKI Jakarta sangat penting dalam upaya menjaga kualitas program kesehatan Ibu Hamil. Tercatat masih banyaknya Angka Kematian Ibu (AKI) dan Angka Kematian Bayi (AKB) di Indonesia, hal ini disebabkan karena salah satu keberhasilan program kesehatan ibu hamil yang baik jika memiliki data dan informasi yang akurat, sehingga pelaku kebijakan kesehatan dapat membuat suatu kebijakan dalam menangani permasalahan tersebut dengan tepat. Tujuan Penelitian ini bertujuan untuk mengetahui pengetahuan petugas, ketersediaan data dan pengawasan pimpinan berhubungan dengan laporan kesehatan Ibu Hamil dari Puskesmas ke Dinas Kesehatan Provinsi DKI Jakarta. Jenis penelitian yang digunakan adalah penelitian kuantitatif dengan desain cross sectional, dengan populasi penelitian sebanyak 44 penanggung jawab pelayanan kesehatan ibu hamil di Puskesmas Kecamatan wilayah kerja Dinas Kesehatan Provinsi DKI Jakarta. Data diperoleh dengan menggunakan kuesioner dan dianalisis dengan menggunakan perangkat lunak statistic untuk uji chi square. Hasil Penelitian dalam penelitian ini menunjukan bahwa variabel pengetahuan dengan nilai p value=0,034 dan variabel ketersediaan data dengan nilai pvalue 0,041 yang artinya kedua variabel tersebut memiliki hubungan yang bermakna dengan keakuratan laporan kesehatan Ibu Hamil, sedangkan variabel pengawasan pimpinan memiliki p value=1,00 yang artinya tidak ada hubungan yang signifikan dengan dengan keakuratan laporan kesehatan Ibu Hamil. Saran dalam penelitian ini adalah Kepala Dinas Kesehatan memberikan akses dan fasilitas dalam peningkatan wawasan secara berkala untuk para petugas kesehatan untuk dapat memahami dengan benar pengisian indikator format laporan kesehatan Ibu Hamil serta membuat suatu kebijakan terkait kewajiban seluruh FKTP dan FKRTL melampirkan bukti telah melakukan pencatatan dan pelaporan rutin setiap bulannya ke Puskesmas Kecamatan yang ada di wilayah masing-masing kedalam persyaratan untuk mendapatkan rekomendasi perizinan dan perpanjangan izin operasional yang perlu dipenuhi kedalam persyaratan ke PTSP dalam menunjang jejaring cakupan ketersediaan data laporan kesehatan Ibu Hamil. Kata Kunci : Pengetahuan, Ketersediaan Data, Pengawasan Pimpinan, Keakuratan Laporan, Kesehatan Ibu Hamil, Puskesmas, Dinas Kesehatan
Analisis Manajemen Risiko Penularan Virus COVID-19 Pada Dokter Dan Perawat Di Rumah Sakit X
Authors: Afifa Tiffani Dwiarine , Adisasmito Wiku Bakti Bawono 
Published: November 2021

Selama pandemi COVID-19, rumah sakit perlu melakukan upaya perlindungan terhadap dokter dan perawat, yaitu dengan penerapan manajemen risiko yang baik. Dalam penelitian ini dilakukan analisis penerapan manajemen risiko terhadap pencegahan penularan infeksi COVID-19 pada dokter dan perawat di RS X dengan cara menganalisis elemen penting dalam penerapannya serta melihat hubungan elemen tersebut terhadap penilaian penerapan manajemen risiko. Penelitian ini menggunakan metode penelitian kuantitatif dan kualitatif paralel konvergen yang diolah secara univariat dan bivariat. Data dikumpulkan melalui wawancara mendalam dan penyebaran kuesioner daring. Hasil: Rumah sakit telah melakukan upaya demi tercapainya lingkungan kerja yang aman, seperti pembuatan area khusus COVID, penyediaan APD yang cukup, serta pengaturan durasi shift. Didapatkan korelasi signifikan (p-value <0.05) elemen yang diteliti dengan penilaian penerapan manajemen risiko, dengan nilai uji Spearman tertinggi 0.607 pada elemen komunikasi dan information. Kesimpulan: Elemen-elemen yang diteliti memiliiki hubungan terhadap penilaian penerapan manajemen risiko di RS X. Telah dilakukan berbagai upaya untuk melindungi dokter dan perawat dengan penerapan manajemen risiko yang sudah berjalan cukup baik, terlihat dari menurunnya angka terinfeksi pada pemeriksaan rutin. Masih ditemukan hambatan berupa keterbatasan sumber daya, karakter yang kurang disiplin, serta belum terciptanya komunikasi dan lingkungan jujur dengan sepenuhnya.Kata kunci: manajemen risiko, COVID-19, dokter, perawat
PEMBELAJARAN MEMBACA MENGGUNAKAN METODE PHONIK DAN MEDIA GAMBAR ANAK TUNAGRAHITA DI SLB NEGERI PRINGSEWU
Authors: Diana Ani 
Published: November 2021

AbstrakPerkembangan ilmu pengetahuan dan teknologi menuntut terciptanya masyarakat yang gemar belajar. Proses belajar yang efektif antara lain dilakukan melalui membaca. Masyarakat yang gemar membaca memperoleh pengetahuan dan wawasan baru yang akan semakin meningkatklan kecerdasan sehingga mereka lebih mampu menjawab tantangan hidup pada masa-masa mendatang, maka membaca diberikan di semua tingkat pendidikan termasuk bagi anak-anak berkebutuhan khusus. Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan peaksanaan metode pembelajaran membaca phonik dan media gambar bagi anak tunagrahita. Subjek penelitian ini anak tunagrahita di SLB Negeri Pringsewu. Teknik pengumnpulan data yang digunakan dalam penelitian ini adalah observasi, wawancara, dan tes hasil belajar. Data yang sudah didapatkan dianalisis dengan metode analisis kualitatif deskriptif. Dari hasil penelitian bahwa pembelajaran membaca menggunakan metode phonik dan media gambar pada 7 anak tunagrahita di SLB Negeri Pringsewu, kemampuan membaca anak-anaknya lebih baik.Kata Kunci: pembelajaran membaca, metode phonik, media gambar, anak tunagrahita. AbstractThe development of science and technology demands the creation of a society that likes to learn. An effective learning process, among others, is done through reading. People who like to read gain new knowledge and insights that will increase their intelligence so that they are better able to answer life's challenges in the future, so reading is given at all levels of education including for children with special needs. This study aims to identify and describe the implementation of learning methods for reading phonics and image media for mentally retarded children. The subject of this research was children with mental retardation in Pringsewu State SLB. The data collection techniques used in this study were observation, interviews, and learning outcomes tests. The data that has been obtained were analyzed using descriptive qualitative analysis method. From the results of the study that learning to read using phonic methods and image media on 7 mentally retarded children in Pringsewu State SLB, their children's reading ability was better.Keywords: reading learning, phonic methods, image media, mentally retarded children.