bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dentre tantos caminhos, uma escolha: das Tecnologias da Informática na escola às Performances Matemáticas Digitais – Trajetória por programas governamentais brasileiros e projetos de pesquisa
Authors: Braga Eduardo dos Santos de Oliveira , Fraga Vinícius Munhoz , Pereira Marcus Vinicius , Rôças Giselle 
Published: June 2021

As Performances Matemáticas Digitais (PMDs) podem ser compreendidas inicialmente como uma perspectiva da Educação Matemática que integra as artes performáticas e tecnologias digitais à Educação Matemática. Levando em consideração as temáticas que envolvem as PMDs – artes e tecnologias digitais - e tendo como inspiração as produções acadêmicas sobre o assunto, o presente artigo tem por objetivo apresentar, a partir de uma das temáticas das PMDs: tecnologias digitais – uma trajetória que se inicia com a entrada da tecnologia informática nas escolas brasileiras até os mais atuais projetos que envolvem discussões das tecnologias digitais com artes e Educação Matemática, por meio das PMDs. Pautados numa metodologia de pesquisa qualitativa, com o estudo particular do evento Encontro Brasileiro de Estudantes de Pós-Graduação em Educação Matemática para descortinar os atuais projetos de pesquisa sobre tecnologias digitais, dividimos esse artigo em duas seções, a saber: a primeira delas se destina a tratar sobre algumas ações governamentais de incentivo às tecnologias digitais nas escolas públicas brasileiras e a segunda descreve a que ponto chegamos em termos de projetos de pesquisa sobre tecnologias digitais na Educação Matemática, enfatizando, para isso, os projetos ligados às PMDs. Conclui-se, dentre outros fatores, que as PMDs se apresentam como uma potente proposta para o ensino e aprendizagem em matemática uma vez que além de articular as tecnologias digitais à Educação Matemática, preocupa-se em incorporar as artes (performáticas) nesse processo, bem como desmistificar estereótipos da matemática e de quem a pratica, dando protagonismo discente em produções oriundas dos diferentes projetos de pesquisa.
Formação complexa de conselheiro linguageiro: Experiência vinculada ao centro de autoacesso Base de Apoio à Aprendizagem Autônoma
Authors: Matos Maria Clara Vianna Sá e , Niwa Sônia Lumi , Carneiro Tiago da Fonseca 
Published: June 2021

O aconselhamento linguageiro é uma atividade ofertada em centros de autoacesso de universidades. Um dos seus papéis é apoiar o processo de aprendizagem de estudantes de línguas estrangeiras no que diz respeito à autonomia e à motivação. A pesquisa “Formação de conselheiro linguageiro com viés empreendedor e o processo motivacional de equipe de centro de autoacesso” tem entre seus objetivos propor caminhos para formar conselheiros linguageiros que possam atuar em centros de autoacesso, bem como em espaços no mercado de trabalho. Nesta pesquisa-ação, realizada sob a abordagem da complexidade, investiga-se como esse fenômeno se desenrola. Alguns do resultados parciais obtidos mostram que: (i) os passos se dão de modo interligado: aprende-se sobre a atividade de aconselhamento exercendo o papel de conselheiro em práticas guiadas com estudantes aconselhados, discutindo as atitudes tomadas e as leituras de apoio sobre o aconselhamento linguageiro, motivação e empreendedorismo; (ii) a configuração do grupo de pesquisa é a de uma dinâmica rede de apoio com conselheiros pesquisadores que apresentam competência linguística diversificada como usuários da língua estrangeira alvo e que frequentam ou já frequentaram o centro de autoacesso no qual este estudo está vinculado, sendo que alguns deles atuam na equipe como voluntários ou bolsistas voltados para gerenciar o espaço e as atividades nele ofertadas.
Aspergilose broncopulmonar alérgica em pacientes com Fibrose Cística
Authors: Santos Júnior Reinaldo José dos , Silva Natália Millena , Souza Pâmella Grasielle Vital Dias de 
Published: June 2021

A fibrose cística (FC) é uma doença genética de perfil autossômico recessivo e é caracterizada pela disfunção do gene CFTR, o que irá afetar alguns órgãos como pulmão, pâncreas, fígado, intestino e testículos, sendo os pulmões o mais acometido. Tais alterações são capazes de provocar obstruções consistentes devido ao muco viscoso produzido. As infecções são um fator recorrente nos portadores dessa doença devido a presença da secreção, tornando-se um ambiente ideal para propagação de micro-organismos, como fungos e bactérias, que podem colonizar as vias aéreas dos pacientes e provocar agravos, piorando o quadro clínico do paciente. Como é o caso do fungo Aspergillus fumigattus, causador da aspergilose broncopulmonar alérgica (ABPA), que pode acarretar relevantes complicações principalmente nas funções pulmonares. Analisando os fatores que faz com que os pacientes com FC tenha maior facilidade em contrair a ABPA e como isso pode agravar seu quadro clínico, com busca de materiais a partir das plataformas PUBMED e SCIELO, utilizando as recomendações do Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), os resultados obtidos nesse estudo mostram que a presença de ABPA nos fibrocísticos favorecem um aumento nas colonizações microbianas, deterioração pulmonar, pior estado nutricional além de maior obstrução respiratória por muco, contribuindo pelo aumento nos índices de hospitalização.
Accurate Identification of Closely Related Mycobacterium tuberculosis Complex Species by High Resolution Tandem Mass Spectrometry
Authors: Bajaj Amol O. , Saraswat Suraj , Knuuttila Juha E. A. , Freeke Joanna , Stielow J. Benjamin , Barker Adam P. 
Published: June 2021

Rapid and accurate differentiation of Mycobacterium tuberculosis complex (MTBC) species from other mycobacterium is essential for appropriate therapeutic management, timely intervention for infection control and initiation of appropriate health care measures. However, routine clinical characterization methods for Mycobacterium tuberculosis (Mtb) species remain both, time consuming and labor intensive. In the present study, an innovative liquid Chromatography-Mass Spectrometry method for the identification of clinically most relevant Mycobacterium tuberculosis complex species is tested using a model set of mycobacterium strains. The methodology is based on protein profiling of Mycobacterium tuberculosis complex isolates, which are used as markers of differentiation. To test the resolving power, speed, and accuracy of the method, four ATCC type strains and 37 recent clinical isolates of closely related species were analyzed using this new approach. Using different deconvolution algorithms, we detected hundreds of individual protein masses, with a subpopulation of these functioning as species-specific markers. This assay identified 216, 260, 222, and 201 proteoforms for M. tuberculosis ATCC 27294™, M. microti ATCC 19422™, M. africanum ATCC 25420™, and M. bovis ATCC 19210™ respectively. All clinical strains were identified to the correct species with a mean of 95% accuracy. Our study successfully demonstrates applicability of this novel mass spectrometric approach to identify clinically relevant Mycobacterium tuberculosis complex species that are very closely related and difficult to differentiate with currently existing methods. Here, we present the first proof-of-principle study employing a fast mass spectrometry-based method to identify the clinically most prevalent species within the Mycobacterium tuberculosis species complex.
A Comparison of Transvaginal Removal and Repair of Uterine Defect for Type II Cesarean Scar Pregnancy and Uterine Artery Embolization Combined With Curettage
Authors: Cao Shanshan , Qiu Guijing , Zhang Peipei , Wang Xinyan , Wu Qing 
Published: June 2021

Background: There is no consensus on a standardized therapy for type II cesarean scar pregnancy (CSP II). The objective of the present study was to evaluate the efficacy and safety and compare costs associated with transvaginal removal and repair (TRR) of uterine defect for CSP II to those of uterine artery embolization (UAE) and curettage.Methods: We conducted a retrospective study that included 87 patients diagnosed with CSP II and treated by performing UAE in combination with curettage and hysteroscopy (n = 53), or TRR (n = 34). Clinical data and outcomes were analyzed.Results: UAE and TRR groups exhibited similar success rates. The TRR group had significantly lower complication rates (30.19 vs. 8.82%, P &lt; 0.05) and lower total costs (13,765.89 ± 2,029.12 vs. 9,063.82 ± 954.67, P &lt; 0.05) than the UAE group. The anterior myometrium of the lower uterine segment was relatively thicker after performing TRR, and no patient suffered from recurrent CSP II. The proportion of patients in the TRR group who had full-term delivery without uterine rupture was 88.24% (30/34), while four patients failed to pregnancy.Conclusion: TRR is a safe and effective treatment method for patients with CSP II and presents a highly cost-effective outcome, especially for patients with future fertility desire.
Accuracy of the Short-Form Montreal Cognitive Assessment Chinese Versions
Authors: Tan Ji-ping , Wang Xiaoxiao , Zhang Shimin , Zhao Yiming , Lan Xiaoyang , Li Nan , Wang Lu-ning , Gao Jing 
Published: June 2021

Background: There is a strong need for short and effective methods to screen for cognitive impairment. Recent studies have created short forms of the Montreal Cognitive Assessment (s-MoCA) in English-speaking populations. It is also important to develop a validated Chinese short version to detect cognitive impairment.Methods: Item response theory and computerized adaptive testing analytics were used to construct abbreviated MoCAs across a large neurological sample comprising 6,981 community-dwelling Chinese veterans.Results: Six MoCA items with high discrimination and appropriate difficulty were included in the s-MoCA. The Chinese short versions (sensitivity 0.89/0.90, specificity 0.72/0.77) are similar in performance to the full MoCA in identifying cognitive impairment (sensitivity 0.91, specificity 0.82).Conclusions: These short variants of the MoCA may serve as quick and effective instruments when the original MoCA cannot be feasibly administered in clinical services with a high patient burden and limited cognitive testing resources.
Active Ingredients and Mechanisms of Change in Motivational Interviewing for Smoking Cessation in Patients With Coronary Artery Disease: A Mixed Methods Study
Authors: Dobber Jos , Snaterse Marjolein , Latour Corine , Peters Ron , ter Riet Gerben , Scholte op Reimer Wilma , de Haan Lieuwe , van Meijel Berno 
Published: June 2021

Background: For patients with coronary artery disease (CAD), smoking is an important risk factor for the recurrence of a cardiovascular event. Motivational interviewing (MI) may increase the motivation of the smokers to stop smoking. Data on MI for smoking cessation in patients with CAD are limited, and the active ingredients and working mechanisms of MI in smoking cessation are largely unknown. Therefore, this study was designed to explore active ingredients and working mechanisms of MI for smoking cessation in smokers with CAD, shortly after a cardiovascular event.Methods: We conducted a qualitative multiple case study of 24 patients with CAD who participated in a randomized trial on lifestyle change. One hundred and nine audio-recorded MI sessions were coded with a combination of the sequential code for observing process exchanges (SCOPE) and the motivational interviewing skill code (MISC). The analysis of the cases consisted of three phases: single case analysis, cross-case analysis, and cross-case synthesis. In a quantitative sequential analysis, we calculated the transition probabilities between the use of MI techniques by the coaches and the subsequent patient statements concerning smoking cessation.Results: In 12 cases, we observed ingredients that appeared to activate the mechanisms of change. Active ingredients were compositions of behaviors of the coaches (e.g., supporting self-efficacy and supporting autonomy) and patient reactions (e.g., in-depth self-exploration and change talk), interacting over large parts of an MI session. The composition of active ingredients differed among cases, as the patient process and the MI-coaching strategy differed. Particularly, change talk and self-efficacy appeared to stimulate the mechanisms of change “arguing oneself into change” and “increasing self-efficacy/confidence.”Conclusion: Harnessing active ingredients that target the mechanisms of change “increasing self-efficacy” and “arguing oneself into change” is a good MI strategy for smoking cessation, because it addresses the ambivalence of a patient toward his/her ability to quit, while, after the actual cessation, maintaining the feeling of urgency to persist in not smoking in the patient.
The COVID-19 Crisis as a Teachable Moment for Lifestyle Change in Dutch Cardiovascular Disease Patients
Authors: Brust Michelle , Gebhardt Winifred A. , Numans Mattijs E. , Kiefte-de Jong Jessica C. 
Published: June 2021

Objective: When lifestyle changes are needed, life events or crises such as COVID-19 may function as “teachable moments”. This study aimed to explore whether the pandemic can provoke a teachable moment regarding lifestyle change in cardiovascular disease patients.Method: In this cross-sectional survey study, 830 cardiovascular disease patients reported their intentions to change lifestyle, instigated by the corona crisis, together with risk perception, affective impact, and changed self-concept, based on a “teachable moments” framework.Results: Between 8 and 28% of the sample reported increased intentions to optimize lifestyle behaviors, particularly related to general lifestyle (28%), physical activity (25%), and diet (21%). Multivariate regression analyses revealed that changed self-concept was associated with higher intentions to improve general lifestyle (B = 0.26; CI = 0.19–0.33), physical activity (B = 0.23; CI = 0.16–0.30), and smoking (B = 0.29; CI = 0.01–0.57). In addition, changed self-concept and affective impact were both significantly associated with higher intentions to improve diet (resp. B = 0.29; CI = 0.21–0.36 and B = 0.12; CI = 0.04–0.21) and to limit alcohol consumption (resp. B = 0.22; CI = 0.13–0.30 and B = 0.11; CI = 0.01–0.20). We did not find evidence for an important role of risk perception on behavior change intentions.Conclusion: The COVID-19 crisis evoked a potential teachable moment for lifestyle change in cardiovascular disease patients, driven by a change in a patient's self-concept and to a lesser extent by an affective impact of the COVID-19 crisis. These results suggest an important window of opportunity for healthcare professionals to utilize the pandemic to promote a healthy lifestyle to their patients.
Comparing Screening Abilities of the 33-Item Hypomania Checklist (HCL-33) and the 33-Item Hypomania Checklist External Assessment (HCL-33-EA) for the Detection of Bipolar Disorder
Authors: Wang Yuan-Yuan , Feng Yuan , Fang Meng , Guo Chengwei , Ungvari Gabor S. , Hall Brian J. , Wang Gang , Xiang Yu-Tao 
Published: June 2021

Background: Bipolar disorder (BD) is a severe psychiatric disorder that is often misdiagnosed and under-diagnosed in clinical settings. The 33-item Hypomania Checklist (HCL-33) is a newly developed self-administered scale for BD detection, while the 33-item Hypomania Checklist-external assessment (HCL-33-EA) is a version of the HCL-33 for external rating used by patient's carer (e.g., family member or friend). We aimed to compare the screening abilities between the HCL-33 and the HCL-33-EA, and evaluate the screening consistency between the two scales.Methods: The data were collected from 269 patients with diagnosed BD (n = 84) or major depressive disorder (MDD) (n = 185). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and area under the curve (AUC) between the HCL-33 and the HCL-33-EA for BD were compared against clinician diagnosis as the gold standard.Results: Using Youden's index, the optimal cut-off value of the HCL-33 is 20, while the corresponding figure for HCL-33-EA is 11. Using Youden's index, the HCL-33-EA showed a better performance than the HCL-33 (0.51 vs.0.41). The HCL-33-EA was more sensitive in correctly identifying BD patients from MDD patients than the HCL-33 (0.83 vs. 0.59), while the HCL-33 presented better specificity than the HCL-33-EA (0.82 vs. 0.68). There was significant screening consistency between the two scales (p &lt; 0.001).Conclusions: Both scales have acceptable psychometric properties in detection BD from MDD. Use of the two scales should be considered based on the assessment purpose in clinical research or daily practice (i.e., prefer sensitivity or specificity). Noticeably, the current sample size is insufficient and future studies are recommended to further evaluate the scales.
Arthroscopically Assisted Cannulated Screw Fixation for Treating Type III Tibial Intercondylar Eminence Fractures: A Short-Term Retrospective Controlled Study
Authors: Zheng Chao , Han Huanli , Cao Yujiang 
Published: June 2021

Background: This study presents the clinical results from 22 children who underwent minimally invasive arthroscopically assisted screw fixation for the treatment of intercondylar eminence fractures.Methods: We retrospectively analyzed the clinical data of 22 children (aged 7.5 to 13.5 years) with type III tibial intercondylar eminence fractures who were treated in our department from March 2007 to September 2019. According to the type of operation, the patients were divided into two groups: group A (n = 12) received arthroscopically assisted cannulated screw fixation, and group B (n = 10) received open reduction and cannulated screw internal fixation. Radiography scans, Lysholm scores, International Knee Documentation Committee (IKDC) 2,000 subjective scores, Tegner scores, range of motion (ROM) of the knee, the anterior drawer test (ADT), the Lachman test, and the pivot-shift test were used to evaluate the clinical efficacy.Results: All 22 children were evaluated over a 12 to 58 month follow-up period (mean: 27.5 months). At the final exam, group A was significantly superior to group B in Lysholm scores (93.33 ± 3.55 vs. 86.20 ± 4.52), IKDC scores (92.06 ± 3.55 vs. 86.07 ± 5.81), and Tegner scores (7.75 ± 0.87 vs. 6.40 ± 0.52) and presented shorter operative times (25.42 ± 3.97 vs. 35.00 ± 5.27). The differences were statistically significant (P &lt; 0.05). All the incisions healed primarily. No complications, such as fracture fragment displacement, delayed epiphyseal growth, or knee joint dysfunction, were observed. The drawer test, Lachman test, and pivot-shift test were negative for all patients.Conclusions: Arthroscopically assisted cannulated screw fixation is effective and safe for the treatment of tibial intercondylar eminence fractures, providing excellent stability and quick recovery of joint function.
Type 2 Nep1-Like Proteins from the Biocontrol Oomycete Pythium oligandrum Suppress Phytophthora capsici Infection in Solanaceous Plants
Authors: Yang Kun , Dong Xiaohua , Li Jialu , Wang Yi , Cheng Yang , Zhai Ying , Li Xiaobo , Wei Lihui , Jing Maofeng , Dou Daolong 
Published: June 2021

As a non-pathogenic oomycete, the biocontrol agent Pythium oligandrum is able to control plant diseases through direct mycoparasite activity and boosting plant immune responses. Several P. oligandrum elicitors have been found to activate plant immunity as microbe-associated molecular patterns (MAMPs). Necrosis- and ethylene-inducing peptide 1 (Nep1)-like proteins (NLPs) are a group of MAMPs widely distributed in eukaryotic and prokaryotic plant pathogens. However, little is known about their distribution and functions in P. oligandrum and its sister species Pythium periplocum. Here, we identified a total of 25 NLPs from P. oligandrum (PyolNLPs) and P. periplocum (PypeNLPs). Meanwhile, we found that PyolNLPs/PypeNLPs genes cluster in two chromosomal segments, and our analysis suggests that they expand by duplication and share a common origin totally different from that of pathogenic oomycetes. Nine PyolNLPs/PypeNLPs induced necrosis in Nicotiana benthamiana by agroinfiltration. Eight partially purified PyolNLPs/PypeNLPs were tested for their potential biocontrol activity. PyolNLP5 and PyolNLP7 showed necrosis-inducing activity in N. benthamiana via direct protein infiltration. At sufficient concentrations, they both significantly reduced disease severity and suppressed the in planta growth of Phytophthora capsici in solanaceous plants including N. benthamiana (tobacco), Solanum lycopersicum (tomato) and Capsicum annuum (pepper). Our assays suggest that the Phytophthora suppression effect of PyolNLP5 and PyolNLP7 is irrelevant to reactive oxygen species (ROS) accumulation. Instead, they induce the expression of antimicrobial plant defensin genes, and the induction depends on their conserved nlp24-like peptide pattern. This work demonstrates the biocontrol role of two P. oligandrum NLPs for solanaceous plants, which uncovers a novel approach of utilizing NLPs to develop bioactive formulae for oomycete pathogen control with no ROS-caused injury to plants.
Masks as Part of Our Novel Identity
Authors: Kefalaki Margarita 
Published: June 2021

Since the time COVID19 made its appearance on an international level (March 2020), masks have become a personal and social identity tool. Nowadays (June 2021), we cannot still leave our house without wearing a mask. It really feels like the mask is now part of our face, covering its lower part, hiding our facial expressions. In this paper, we examine the place and use of masks as markers of personal and social identities, as well as social responsibility. More particularly, we observe the following three issues: a) the symbolic meaning of masks as an anthropological artifact, b) the dilemma of individual liberty balanced by social responsibility, produced through mask wearing, and c) the way we can create meaning through adaptation to a new “masked reality”. In this article, based on personal experiences, observation and bibliographical research, we explore and reveal the symbolic meaning of masks. We make use of the social identity theory (SIT) that assumes that one part of the self-concept is defined by our belonging to social groups (Trepte, 2006). More particularly we are examining our identity’s, personal and social, need to respond to the ‘obligation’ of mask wearing. We believe that finding or inventing meaning to the use of mask, can help us evolve and accept our new reality.
DEVELOPMENT OF CONCRETE MODIFIED ON POLYCARBOXYLATE SUPERPLASTICATOR
Authors: Саламанова М. Ш. , Аласханов А. Х. , Габашев А. А. , Мовсулов М. М. 
Published: June 2021

Представлены результаты разработки высококачественных бетонов линейки классов от В7,5 до В30 с использованием местных сырьевых материалов и суперпластификатора на основе эфиров поликарбоксилатов. С использованием добавки MasterPozzolith 3150W проведены исследования по изучению динамики набора прочности, жизнеспособности, подвижности и склонности к седиментации бетонной смести, что благоприятно отразится на перекачиваемости и формовании конструкций.
The results of the development of high-quality concretes of a line of classes from B7.5 to B30 using local raw materials and a superplasticizer based on polycarboxylate ethers are presented. Using the additive MasterPozzolith 3150W, studies have been carried out to study the dynamics of strength gain, viability, mobility and the tendency to sedimentation of concrete sweep, which will have a beneficial effect on the pumpability and formation of structures.