bluuebunny/crossref_metadata_2025_split huggingface dataset:
RELAÇÃO ENTRE AS PRÁTICAS DOS DOCENTES NA REDE PÚBLICA MUNICIPAL DE ENSINO COM O MATERIAL PADRONIZADO APOSTILADO
Authors: Do Prado Jefferson Antonio 
Published: March 2021

Este artigo aponta a relação entre o trabalho dos docentes em uma rede pública municipal e a utilização do material apostilado utilizado em sala de aula. O estudo partiu de uma revisão bibliográfica e realizou uma pesquisa qualitativa através de um questionário aplicado a professores de língua portuguesa em escolas municipais no interior de São Paulo. Tais docentes trabalham vinculados à secretaria de Educação a qual, por meio de licitação pública, utiliza os didáticos apostilados produzidos por uma empresa que pertence ao mercado editorial educacional. Os resultados investigados apontam que tais apostilas de ensino advindos de um mercado de editoração educacional, ainda que organizem, definam e programem o trabalho pedagógico do professor, estabelecem parâmetros e regras que direcionam o funcionamento e, sobretudo, controlam os comportamentos, procedimentos e resultados de diretores, coordenadores, alunos e, em especial, dos docentes que se apropriam do material.
PRÓS E CONTRAS DO ENSINO REMOTO
Authors: Fuckner Malton de Oliveira 
Published: March 2021

O texto propõe uma reflexão sobre aulas remotas no contexto de suspensão do ensino presencial devido à pandemia do Covid-19. Sob a análise crítica de Alves (2020), por meio de um estudo de caso utilizando o projeto Conexão como objeto de análise, procurou-se propor um contraponto aos argumentos contrários à adoção das aulas remotas no ensino privado. O projeto Conexão compreende aulões por meio de lives e videoconferência no contraturno para turmas de ensino médio. O estudo de caso usou questionário, registros eletrônicos do YouTube, WhatsApp e o aplicativo mentimeter.com, além de fontes documentais, como campo de pesquisa. Inferiu-se que, devidamente inteirados, escola, família e estudantes têm diante de si elementos suficientes para a construção de aulas online a fim de adotá-las de forma sistemática, ainda que com limitações.
QUALIDADE DE VIDA E TRABALHO DOCENTE NO ENSINO SUPERIOR: UMA RELAÇÃO ANTAGÔNICA
Authors: Ferreira da Silva Jeann Bruno , Da Rocha Silva Mônica Aparecida , Rodrigues Waldecy 
Published: March 2021

Introdução: os docentes do ensino superior no Brasil além de lecionar aulas, dividem suas atribuições entre projetos de extensão, orientações de discentes e pesquisas acadêmicas. A crescente oferta de matrículas no ensino superior e a criação de novas universidades tem ampliado também a criação de programas de pós-graduação. Este processo, naturalmente capacita o docente para multifacetar sua atuação, seja por meio de programas de mestrado ou doutorado. Objetivo: analisar a produção científica acerca da Qualidade de Vida (QV) de Docentes do Ensino Superior. Metodologia: pesquisa bibliográfica de natureza descritiva com abordagem cienciométrica para análise e tratamento dos dados. Resultados e discussão: foram encontradas 78 publicações e, ao aplicar os critérios de inclusão e exclusão, restaram o total de 22. A maioria dos artigos (45%) foram publicados no ano de 2015, 36% foram publicados na região Sul, dos autores principais 54% possuem titulação de doutor, 45% objetivaram avaliar a QV dos profissionais docentes e as classificações de maior prevalência foram A2 e A1. Considerações finais: pontuou-se a escassez de pesquisas no sobre a temática na base de dados da SsciELO e que é necessário tornar visível o processo de trabalho destes profissionais para possíveis intervenções no âmbito universitário.
.
Palavras-chave: qualidade de vida; docente; ensino superior.
Sucker Rod Antibuckling System: Development and Field Application
Authors: Langbauer Clemens , Fruhwirth Rudolf Konrad , Volker Lukas 
Published: March 2021

SummaryWhen the oil price is low, cost optimization is vital, especially in mature oil fields. Reducing lifting costs by increasing the mean time between failure and the overall system efficiency helps to keep wells economical and increase the final recovery factor. A significant portion of artificially lifted wells currently use sucker rod pumping systems. Although its efficiency is in the upper range, there is still room for improvement compared with other artificial-lift systems.This paper presents the field-tested sucker rod antibuckling system (SRABS), which prevents buckling of the entire sucker rod string, achieved by a redesign of the standing valve, the advantageous use of the dynamic liquid level, and, on a case-by-case basis, application of a tension element. The system allows full buckling prevention and a reduction of the overall stresses in the sucker rod string.The resulting reduction in the number of well interventions combined with the higher system efficiency prolongs economic production in mature oil fields, even in times of low oil prices. The analysis of SRABS, using finite-element simulations, showed a significant increase in system efficiency. The SRABS performance and wear tests under large-scale conditions were performed at Montanuniversität Leoben’s Pump Test Facility and in the oil field. The results of intensive laboratory testing were used to optimize the pump-body geometry and improve the wear resistance by selecting optimal materials for the individual pump components. The ongoing field-test evaluation confirmed the theoretical approach and showed the benefits achieved by using SRABS. SRABS itself can be applied within every sucker rod pumping system; the installation is as convenient as a standard pump, and manufacturing costs are comparable with those of a standard pump.This paper shows improved performance of the SRABS pumping system compared with a standard sucker rod pump. SRABS is one of the first systems that prevents the sucker rod string from buckling without any additional equipment, such as sinker bars. Testing of SRABS has identified significant benefits compared with standard sucker rod pumps.
Novel Two-stage Nonlinear Interconnected Unknown Input Observer Design: Hardware &amp; Experimental Vehicle Validation
Authors: FOUKA Majda , SENTOUH Chouki , POPIEUL Jean-Christophe 
Published: March 2021

Abstract
This paper concerns both vehicle lateral and longitudinal nonlinear dynamics estimation. Consequently, the interlinked vehicle models dependency and the hurdle coupling features will be overcome here thanks to the NONLINEAR INTERCONNECTED UNKNOWN INPUTS OBSERVER (NI-UIO) framework. This interconnection scheme extends the estimation of the lateral motion to the longitudinal one with the unknown accelerator, brake pedal and driver steering torque inputs, as well as tire-ground pneumatic efforts to reduce conservatism and observability problems. The aspects of immeasurable real-time variation in the forward speed and tire slip velocities in front and rear wheels are taken particularly into account. Consequently, TAKAGI-SUGENO (TS) fuzzy form is undertaken to deal with these nonlinearities in the observer synthesis. The INPUT TO STATE STABILITY (ISS) of the estimation errors is exploited using Lyapunov stability arguments to allow more relaxation and additional robustness guarantee regarding the disturbance term of immeasurable nonlinearities. Therein, sufficient conditions of the ISS property are formulated as an optimization problem in terms of linear matrix inequalities (LMIs). Finally, hardware and experimental validation with robustness test are performed with the well-known SHERPA dynamic interactive driving simulator as well as TWINGO vehicle prototype to highlight performances and applicability of the outlined observer.
A Novel Memcapacitor and Its Application in a Chaotic Circuit
Authors: Guo Mei , Yang Ran , Zhang Meng , Liu Renyuan , Zhu Yongliang , Dou Gang 
Published: March 2021

Abstract
In this paper, a novel memcapacitor is designed by SBT memristor and two capacitors. A fifth-order memcapacitor and memristor chaotic circuit is proposed. The stability of the equilibrium point of the system is analyzed theoretically. Lyapunov exponents spectra, bifurcation diagrams, poincaré maps and phase diagrams are used to analyze the dynamic behaviors of the system. The results show that under different initial values and parameters, the system produces rich dynamic behaviors such as stable points, limit cycles, chaos, and so on. Specially, coexisting attractors, transient chaos, and steady-state chaos accompanied by burst period phenomenon are also produced in the system. The proposed memcapacitor-based circuit expands the research methods of memcapacitor for application in chaoticcircuits.
Sorption and transport of Mn2+ in soil amended with alkali modified pomelo biochar
Authors: An Qiang , Zhu Sheng , Li Zheng , Deng Shu-man , Zhao Bin , Meng Fanyu , Jin Ningjie , Ren Xiaozhou 
Published: March 2021

Abstract
Owing to its effectiveness and environment-friendly, biochar has been used for adsorbing and immobilizing pollutants in soil in recent years of studies, which is also suitable for manganese pollution in soil caused by manganese mining and processing activities. In this research, alkali modified pomelo biochar (MBC) was regarded as a soil amendment, the improvement of soil physicochemical properties as well as Mn 2+ sorption and transport in soil by modifying with MBC were investigated. In incubation experiment, 0-10% (w/w) MBC addition amount significantly improved the physicochemical properties of soil. Due to the amelioration of soil physicochemical properties along with the oxygen-containing functional groups and the developed pore structure of MBC itself, the adsorption capacity of MBC modification soil towards Mn 2+ (q e ) was enhanced in batch adsorption experiment, and q e increased by 10-108% when MBC ratio grew from 0 to 10% at 300 mg·L -1 Mn 2+ solution. In column migration experiment, the Mn 2+ retention rate climbed by 13-106% from 0 to 10% MBC addition proportion when adopted the MBC filling way that placed MBC on the soil upper layer , and the reinforced restriction on Mn 2+ transport in soil amended with MBC might ascribe to the enhanced q e as well as the reduced saturated hydraulic conductivity. These results proved that MBC effectively augmented adsorption ability and suppressed transport of Mn 2+ in soil, which could provide an available mind on prevention and remediation of soil Mn contamination.
Endoscopic Submucosal Dissection for Early-Stage Neuroendocrine Carcinoma of The Esophagus ：A Case Report
Authors: Tang Nan , Cheng Zhonghua , Fen Zhen 
Published: March 2021

Abstract
Background: Neuroendocrine carcinoma (NEC) of the esophagus is rare, highly aggressive and lacks biological features. Case presentation: In this report, we describe a patient with Esophageal NEC who was successfully treated using endoscopic submucosal dissection (ESD). A 55-year-old woman presented with intermittent mild dysphagia for 2 months. Gastroscopy revealed a disc-shaped protruding lesion about 18mm×18mm in size on the upper esophagus, 25cm from the incisors. Endoscopic ultrasonography (EUS) demonstrated the bulged lesion was highly echoic and homogeneous, originating from the muscularis mucosa. We assessed en bloc resection by ESD for therapeutic diagnosis to be a safe and appropriate treatment. The tumor was removed using ESD. Histopathological examination revealed a poorly differentiated neoplasm comprising large cells with marked nuclear atypia and multifocal necrosis Immunohistochemistry staining revealed tumor tissue that was positive for Ki67, CgA, Syn, CD56, but negative for P40, P63, S-100 protein. These histopathological results were consistent with a diagnosis of esophageal NEC, large cell type, derived from the muscularis mucosae. After comprehensive consideration, we adopted the combination treatments (ESD plus an adjuvant chemotherapy). The patient has been followed up till now with no recurrence. Conclusions: En bloc resection approach by ESD play a vital role in the early therapeutic diagnosis of esophageal NEC.
Reliability and Efficacy of Maximum Fluorescein Tear Break-Up Time in Diagnosing Dry Eye Disease
Authors: Mou Yujie , Xiang Huan , Lin Lin , Yuan Kelan , Wang Xin , Wu Yaying , Min Jinjin , Jin Xiuming 
Published: March 2021

Abstract
This study aims to investigate the reliability and efficacy of maximum fluorescein tear break-up time (FTBUTmax) in diagnosing dry eye disease (DED). 147 participants were enrolled in this study. Ocular symptoms were assessed by Ocular Surface Disease Index (OSDI). The fluorescein tear break-up time (FTBUT) examination, corneal fluorescein staining (CFS), and Schirmer I test were performed on both eyes. Each participant underwent 3 consecutive FTBUT tests, and five types of FTBUT values including FTBUTmax, the minimum FTBUT (FTBUTmin), the first FTBUT (FTBUT1), the average of three FTBUTs (FTBUT123) and the average of the first and second FTBUT (FTBUT12) were recorded. FTBUTmax was larger than the other FTBUT values, but no differences were found among the values of FTBUT1, FTBUT123, FTBUT12 and FTBUTmin. In the ROC analysis, FTBUTmax had the largest or the second largest area under the ROC (AUROC) in all three DED diagnostic criteria, while FTBUTmin had the least AUROC of them. ROC efficacy of FTBUTmax was significantly higher than that of FTBUT123, FTBUT12, FTBUT1 and FTBUTmin in the OSDI criteria and higher than that of FTBUT1 and FTBUTmin in Schirmer and CFS tests. FTBUTmax has a close correlation with OSDI, Schirmer I test and CFS, and is an effective tool for the DED diagnosis.
Using Gated Recurrent Units Models for Early Prediction of Sepsis in The Intensive Care Unit
Authors: Zhao Xuze , Qu Bo 
Published: March 2021

Abstract
Background: Sepsis is one of the major causes of mortality in hospitalized patients. Therefore, a reliable means of predicting sepsis onset is of great importance. The purpose of this study was to develop a gated recurrent unit (GRU) based model and explore whether it can improve model performance in predicting sepsis for up to 6h from the time of admission in intensive care units (ICU) compared to traditional sepsis prediction methods. Methods: The data used for model development in this study were from retrospective MIMIC-III dataset, restricted to intensive care units (ICUs) patients aged between 15 and 89. Model performance of GRU model were compared to logistic regression (LR), support vector machine (SVM), random forest (RF), and extreme gradient boost (XGBoost). The area under the receiver operating characteristic (AUROC) measures the performance of the prediction capability of the models. Results: A total of 31297 MIMIC-III cases are included in this article and 4008 cases had encountered sepsis while 27289 had not. As for the AUC (0.801 (95% CI): 0.760-0.841), 0.782 (95%CI: 0.743-0.821), 0.775 (95%CI: 0.736-0.813), 0.771 (95%CI: 0.732-0.809), 0.749 (95%CI: 0.711-0.886),) results of the models, GRU performed best in predicting sepsis.Conclusions: The present study concluded that by using GRU deep learning method, a more accurate prediction model can be established. The GRU deep learning method we build can prove clinically helpful and assist physicians in tailoring accurate management and treatment for patients with sepsis.
Transfection of STAT3 Overexpression Plasmid Mediated by Recombinant Lentivirus Promotes Differentiation of Bone Marrow Mesenchymal Stem Cells Into Neural Cells in Fetal Rats With Spina Bifida Aperta
Authors: Jiang mingyu , Dai Ji-cheng , Yin Ming-ying , Ren Ming-yong 
Published: March 2021

Abstract
Background

To investigate the influence of signal transducer and activator of transcription-3 (STAT3) on spinal cord tissue grafts of rat fetuses with spina bifida aperta. In particular, we wished to determine if STAT3 overexpression plasmid transfection would increase survival of spinal cord transplantation to improve therapeutic efficiency.
Methods

The fetal rat model of spina bifida aperta was established by retinoic acid and treated by microsurgical injection of stem cells. They were divided into blank control group (n = 12), negative control group (n = 10) and experimental group (n = 11). The optical density (OD) value of BMSCs viability was determined by Cell Counting Kit-8 (CCK-8). The expression of STAT3, pSTAT3, nerve markers (Glial fibrillary acidic protein, Neuron-specific enolase, Neurofilament and Nestin) and apoptosis related factors (Caspase 8 and Bcl-2) were tested by the method of real-time PCR and Western blot. All statistical analyses were performed using SPSS version 20.0 software. One-way analysis of variance was used to analyze differences among three or more groups. The data are presented as the mean ± standard deviation from at least three independent experiments. P < 0.05 was considered statistically significant.
Results

OD value in experimental group was the highest at 8 hours after transplantation by CCK-8, and then gradually decreased, which was statistically significant compared with blank control group and negative control group (P < 0.05). There was no statistical difference in OD peak time and value between blank control group and negative control group. The expression levels of pSTAT3, Glial fibrillary acidic protein, Neuron-specific enolase, Neurofilament and Nestin in experimental group were remarkably higher than those in blank control group and negative control group (P < 0.05), but STAT3 expression in experimental group were statistically decreased (P < 0.05). The relative expression levels of Caspase-8 and Bcl-2 in experimental group were tremendously lower than those in blank control group and negative control group (P < 0.05).
Conclusion

Transfection of recombinant lentivirus mediated STAT3 overexpression plasmid with BMSCs can improve the efficiency of transforming into neural cells and provide new seed cells for the treatment of congenital spina bifida aperta.
Effects of Sweet Potato Vine Silage Supplementation on Meat Quality, Antioxidant Capacity and Immune Function in Finishing Pigs
Authors: Wang Ruibo , Sun Bo , Yue Zhiyuan , Zheng Hao , Zhou Qinglong , Bao Chunna , Shi Baoming , Shan Anshan , Ma Qingquan 
Published: March 2021

Abstract
Background

Sweet potato vine is the stem and leaf of sweet potato and is nutritious as feedstuff. Silage is an effective solution to retain nutritional value and is beneficial for the preservation. This article explored the effects of Sweet potato vine silage (SPVS) supplementation on meat quality, antioxidant capacity and immune function in finishing pigs. 180 finishing pigs (Berkshire×Licha Black) with body weight of 74.54 ± 3.32 kg were randomly divided into three groups with six pigs per pen and six replicate per treatment: control diet (CON), CON supplemented with 2.5% SPVS (LSPVS) and 5.0% SPVS (HSPVS).
Results

It showed that eye muscle area in the LSPVS group was significantly increased and carcass weight in the HSPVS was significantly reduced. Cooking loss in both HSPVS and LSPVS were significantly reduced. Hepatic level of glutathione peroxidase (GSH-PX) was significantly upregulated in LSPVS but downregulated in HSPVS. In serum, HSPVS decreased glutathione (GSH) level and increased GSH-PX level. HSPVS significantly reduced hepatic IL-1 level and LSPVS significantly reduced IL-12 level and increased IL-8 level. Moreover, HSPV promoted the secretion of IgM and IgG in serum.
Conclusions

SPVS supplementation improved animal performance, meat quality, antioxidant capacity and immune performance in finishing pigs, which provide a new alternative to improve animal health and substitute traditional feedstuff.
Renal function in Japanese HIV-1-positive patients who switch to tenofovir alafenamide fumarate after long-term tenofovir disoproxil fumarate
Authors: Abe Kensuke , Obara Taku , Kamio Satomi , Kondo Asahi , Imamura Junji , Goto Tatsuya , Ito Toshihiro , Sato Hiroshi , Takahashi Nobuyuki 
Published: March 2021

Abstract
BACKGROUND Tenofovir disoproxil fumarate (TDF) has a strong antiviral effect, but TDF is known to cause renal dysfunction. Therefore, we are investigating preventing renal dysfunction by replacing TDF with tenofovir alafenamide fumarate (TAF), which is known to be relatively safe to the kidneys. However, the changes in renal function under long-term use of TAF are not known. In this study, we evaluated renal function in Japanese HIV-1-positive patients switching to TAF after long-term treatment with TDF.METHODS A single-center observational study was conducted in Japanese HIV-1-positive patients. TDF was switched to TAF after at least 48 weeks of treatment so we could evaluate the long-term use of TDF. The primary endpoint was the estimated glomerular filtration rate (eGFR) at 144 weeks of TAF administration. In addition, we predicted the factors that would lead to changes in eGFR after long-term use of TAF.RESULTS Of the 125 HIV-1-positive patients who were prescribed TAF at our hospital during the study period, 70 fulfilled the study criteria. The eGFR at the time of switching from TDF to TAF was 81.4 ± 21.1 mL/min/1.73 m2. eGFR improved significantly after 12 weeks of taking TAF but significantly decreased at 96 and 144 weeks. At 144 weeks of taking TAF, the factors significantly correlated with the difference in eGFR from baseline were the difference in eGFR at 48 weeks of taking TAF and age at the start of TAF.CONCLUSIONS In this study, Japanese HIV-1-positive patients who had been taking TDF for a long period of time showed a decrease in eGFR after switching to long-term use of TAF. Japanese HIV-1-positive patients are expected to take TAF for a long time. Depending on age, laboratory values related to renal function need to be monitored carefully.
Changes in Genetic Diversity and Demographic History of Jankowski’s Bunting (Emberiza Jankowskii), as Revealed by Mitochondrial DNA and Microsatellite Markers
Authors: Huang Long , Feng Guochen , Li Dan , Shang Weiping , Zhang Lishi , Yan Rongfei , Jiang Yunlei , Li Shi 
Published: March 2021

Abstract
The genetic variation and distribution of a population depend largely on the demographic history. For instance, populations that have recently experienced shrinkage usually have a lower genetic diversity. However, some endangered species with a narrow distribution have a high genetic diversity resulting from large historical population sizes and long generation times. In addition, very recent population bottlenecks may not be reflected in the population’s genetic information. In this study, we used a mitochondrial DNA marker and 15 microsatellite markers to reveal the genetic diversity, recent changes, inbreeding, and demographic history of a Jankowski’s bunting (Emberiza jankowskii) population in eastern Inner Mongolia. The results show that the genetic diversity of the population remained at a relatively stable and high level until recently. Severe population shrinkage did not result in a considerable lack of genetic variation because of the large historical population size and relatively short periods of human disturbance. In addition, introgression and gene flow among populations compensate for the loss of genetic variation to some extent. Considering the current small effective population size and the existence of inbreeding, we recommend that habitat protection be continued to maximize the genetic diversity of the Jankowski’s bunting population.