bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN ANTARA MOTIVASI MENJADI GURU DENGAN NILAI KETERAMPILAN MENGAJAR MAHASISWA PKM
Authors: Martini Lisdewi , Soeprijanto  , Wadjdi Faried 
Published: March 2021

This research aims to determine of the relationship between motivation being a teacher and the value of PKM students teaching skills. In this research using quantitative approach with descriptive-correlative method. The population and sample in this research is the students in Electrical Engineering Department, Faculty of Engineering, State University of Jakarta. The technique of data collection is hypothesis test, t-test with previously performed prerequisite analysis test: normality test and linearity test.The calculation results shows that hypothesis test with significance level of 5% obtained rcount = 0,4685 and rtable = 0,230 rcalculated > rtable then the value that of tcalculated = 4,04652 and ttabel = 1,998 which tcalculated > ttabel then its shows that there is positive and significant relationship between motivation being a teacher and the value of PKM students teaching skills. This research contributes to the world of education about the relationship between motivation being a teacher and the value of PKM students teaching skills and being a reference material for the next research, so the learning that gives is able to encourage or increase motivation being a teacher for students.
ABSTRAK
Penelitian ini bertujuan untuk mengetahui hubungan antara motivasi menjadi guru dengan nilai keterampilan mengajar mahasiswa PKM. Pada penelitian ini menggunakan pendekatan kuantitatif dengan metode deskriptif korelatif. Populasi dan sampel dalam penelitian adalah mahasiswa Program Studi Teknik Elektro Fakultas Teknik Univeristas Negeri Jakarta. Teknik analisis data yang digunakan adalah uji hipotesis dan uji-t yang sebelumnya dilakukan uji prasyarat analisis menggunakan uji normalitas dan uji linieritas. Hasil penelitian menunjukan bahwa uji hipotesis dengan taraf signifikansi 5% diperoleh nilai rhitung = 0,4685 dan nilai rtabel = 0,230, kemudian nilai thitung sebesar = 4,04652 dan nilai ttabel sebesar = 1,998 dimana thitung > ttabel maka menunjukan terdapat hubungan yang positif dan signifikan antara motivasi menjadi guru dengan nilai keterampilan mengajar mahasiswa PKM. Penelitiam ini memberikan kontribusi pada dunia pendidikan mengenai hubungan antara motivasi menjadi guru dengan nilai keterampilan mengajar mahasiswa PKM dan menjadi bahan referensi untuk penelitian selanjutnya, sehingga pembelajaran yang diberikan mampu mendorong atau meningkatkan motivasi menjadi guru pada mahasiswa.
Combined effects of predicted climate and land use changes on future hydrological droughts in the Luanhe River basin, China
Authors: Chen Xu , Han Ruiguang , Wang Yongjie 
Published: March 2021

Abstract
Drought can be impacted by both climate change and land use change in different ways. Thus, in order to predict future drought conditions, hydrological simulations as an ideal means, can be used to account for both projected climate change and projected land use change. In this study, projected climate and land use changes were integrated with the SWAT (Soil and Water Assessment Tool) model to estimate the combined impact of climate and land use projections on hydrological droughts in the Luanhe River basin. We presented that the measured runoff and the remote sensing inversion of soil water content were simultaneously used to validate the model to ensure the reliability of model parameters. Following the calibration and validation, the SWAT model was forced with downscaled precipitation and temperature outputs from a suite of nine Global Climate Models (GCMs) based on the CMIP5, corresponding to three different representative concentration pathways (RCP 2.6, RCP 4.5 and 8.5) for three distinct time periods: 2011–2040, 2041–2070 and 2071–2100, referred to as early-century, mid-century and late-century, respectively, and the land use predicted by CA-Markov model in the same future periods. Hydrological droughts were quantified using the Standardized Runoff Index (SRI). Compared to the baseline scenario (1961–1990), mild drought occurred more frequently during the next three periods (except the 2080s under the RCP2.6 emission scenario). Under the RCP8.5 emission scenario, the probability of severe drought or above occurring in the 2080s increased, the duration prolonged and the severity increased. Under the RCP2.6 scenario, the upper central region of the Luanhe river in the 2020s and upper reaches of the Luanhe river in the 2080s, were more likely to suffer extreme drought events. And under the RCP8.5 scenario, the middle and lower Luanhe river in the 2080s, were more likely to suffer these conditions.
Therapeutic effect of EGF secreted by human umbilical cord blood-derived mesenchymal stem cells on atopic dermatitis
Authors: Jung Namhee , Kong TaeHo , Yu Yeonsil , Park Hwanhee , Lee Eunjoo , Yoo SaeMi , Baek Song Yi , Lee Seunghee , Kang Kyung-Sun 
Published: March 2021

Abstract
Human mesenchymal stem cells (MSCs) are emerging as a treatment for atopic dermatitis (AD), which is a common inflammatory skin disorder that affects a large number of people across the world. Treatment of AD using human umbilical cord blood-derived MSCs (hUCB-MSCs) has recently been studied; however, the mechanism underlying the effects of these cells is unclear. This study investigated the effect of epidermal growth factor (EGF) secreted by hUCB-MSCs on AD. hUCB-MSCs secreted a high concentration of EGF compared with other cell types. To elucidate the effect of EGF secreted by hUCB-MSCs, EGF expression was downregulated in hUCB-MSCs using EGF-targeting small interfering RNA, and these cells were co-cultured with keratinocytes, Th2 cells, and mast cells. Depletion of EGF expression disrupted the immunomodulatory effects of hUCB-MSCs on these AD-related inflammatory cells. In a Dermatophagoides farinae-induced AD mouse model, subcutaneous injection of hUCB-MSCs ameliorated gross scoring, histopathologic damage, and mast cell infiltration, and significantly reduced the levels of inflammatory cytokines including interleukin (IL)-4, tumor necrosis factor-α (TNFa), thymus and activation-regulated chemokine (TARC), and IL-22, as well as the serum IgE level. These therapeutic effects were significantly attenuated at all evaluation points in mice injected with EGF-depleted hUCB-MSCs. Taken together, these results suggest that EGF secreted by hUCB-MSCs plays an important role in treatment of AD by regulating the inflammatory response in keratinocytes, Th2 cells, and mast cells.
Main role of antibodies in demyelination and axonal damage in Multiple Sclerosis
Authors: Muñoz Úrsula , Sebal Cristina , Escudero Esther , Esiri Margaret , Tzartos John , Sloan Carolyn , Sadaba Mari Cruz 
Published: March 2021

Abstract
Background
Antibodies and oxidative stress are hallmarks of multiple sclerosis (MS) lesions. We aimed to clarify the relation between them, their role in MS patients, and to investigate their specificity, comparing MS with classical neurodegenerative diseases (ND).
Methods
Brain samples from 14 MS cases, 6 with ND and 9 without neurological diseases (controls). Immunohistochemistry assays were used to detect oxidized lipids (EO6), IgG and IgM, oligodendrocytes (Olig2), axons (NF, neurofilament) and cellular (TUNEL) and axonal damage (APP, amyloid precursor protein).
Results
We did not observe EO6 in controls. All samples from MS patients showed EO6 in oligodendrocytes and axons within lesions. We did not detect co-localization between EO6 and antibodies. Neither did we between EO6 and TUNEL or APP. 94.4% of TUNEL positive cells in normal appearing white matter were also stained for IgG and 75.5% for IgM. IgM, but not IgG co-localized with APP. EO6 was associated with axonal damage in amyotrophic lateral sclerosis (ALS). We did not observe association between antibodies and cellular or axonal damage in ND patients. MS patients showed a higher number of B cells and plasma cells in the lesions and meninges than controls. The number of B cells and plasma cells was associated with the presence of antibodies and with the activity of the lesions.
Conclusions
We observed a main role of B-lymphocytes in the development of MS lesions. Antibodies contribute to the oligodendrocyte and axonal damage in MS. Oxidative stress was associated with axonal damage in ALS.
Seed longevity studies in wild type, cultivated and inter-specific recombination inbred lines (RILs) of soybean
Authors: Chandra Subhash , Talukdar Akshay , Taak Yashpal , Yadav Raju R. , Saini Manisha , Sipani N. S. 
Published: March 2021

Abstract
Loss of seed viability is a serious hurdle in higher production and ambient seed storage of soybean. Understanding the factors affecting seed viability and identification of soybean genotype(s) with higher viability is critical for higher soybean production. In this study, seeds of 125 soybean genotypes of three different species (Glycine tomentella, Glycine soja and Glycine max) and 25 RILs (Glycine soja × Glycine soja) were tested for germination immediately after harvest followed by one, two and three years of ambient storage. Fresh seeds of all the genotypes recorded 78-99% germination with a mean of 94.02%. However, the mean value of per cent germination of all the genotypes after one, two and three years of ambient storage decreased and found to stand at 79.51%, 52.24% and 29.18%, respectively. Among the genotypes tested, G. tomentella accession registered highest seed storability followed by G. soja, RILs and G. max. After three years of storage, 14 wild type genotypes and 3 RILs maintained >70% germination and identified as ‘good storers’. Genetic divergence studies via k-mean clustering and principal component analysis grouped all genotypes in three cluster/component based on seed size, seed coat permeability and seed viability. Seed viability was significantly and negatively correlated with electrical conductivity. Good storers found to be having slow imbibition rate than poor storers in initial hours of imbibition. The good storing genotypes identified in this study will serve as an elite soybean genetic resource in developing the soybean cultivars with better seed longevity.
Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalized adults
Authors: Self Wesley H. , Stewart Thomas G. , Wheeler Allison P. , Atrouni Wissam El , Bistran-Hall Amanda J. , Casey Jonathan D. , Cataldo Vince D. , Chappell James D. , Cohn Claudia S. , Collins Jessica B. , Denison Mark R. , de Wit Marjolein , Dixon Sheri L. , Duggal Abhijit , Edwards Terri L. , Fontaine Magali J. , Ginde Adit A. , Harkins Michelle S. , Harrington Thelma , Harris Estelle S. , Hoda Daanish , Ipe Tina S. , Jaiswal Stuti J. , Johnson Nicholas J. , Jones Alan E. , Laguio-Vila Maryrose , Lindsell Christopher J. , Mallada Jason , Mammen Manoj J. , Metcalf Ryan A. , Middleton Elizabeth A. , Mucha Simon , O'Neal Hollis R. , Pannu Sonal R. , Pulley Jill M. , Qiao Xian , Raval Jay S. , Rhoads Jillian P. , Schrager Harry , Shanholtz Carl , Shapiro Nathan I. , Schrantz Stephen J. , Thomsen Isaac , Vermillion Krista K. , Bernard Gordon R. , Rice Todd W. 
Published: March 2021

Abstract
Background: Convalescent plasma is being used widely as a treatment for coronavirus disease 2019 (COVID-19). However, the clinical efficacy of COVID-19 convalescent plasma is unclear. Methods: The Passive Immunity Trial for Our Nation (PassITON), is a multicenter, placebo-controlled, blinded, randomized clinical trial being conducted in the United States to provide high-quality evidence on the efficacy of COVID-19 convalescent plasma as a treatment for adults hospitalized with symptomatic disease. Adults hospitalized with COVID-19 with respiratory symptoms for less than 14 days are eligible. Enrolled patients are randomized in a 1:1 ratio to 1 unit (200-399 mL) of COVID-19 convalescent plasma that has demonstrated neutralizing function using a SARS-CoV-2 chimeric virus neutralization assay. Study treatments are administered in a blinded fashion and patients are followed for 28 days. The primary outcome is clinical status 14 days after study treatment as measured on a 7-category ordinal scale assessing mortality, respiratory support, and return to normal activities of daily living. Key secondary outcomes include mortality and oxygen-free days. The trial is projected to enroll 1000 patients and is designed to detect an odds ratio ≤ 0.73 for the primary outcome. Discussion: This trial will provide the most robust data available to date on the efficacy of COVID-19 convalescent plasma for the treatment of adults hospitalized with acute moderate to severe COVID-19. These data will be useful to guide the treatment of COVID-19 patients in the current pandemic and for informing decisions about whether developing a standardized infrastructure for collecting and disseminating convalescent plasma to prepare for future viral pandemics is indicated. Trial Registration: ClinicalTrials.gov: NCT04362176. Date of trial registration: April 24, 2020, https://clinicaltrials.gov/ct2/show/NCT04362176
Identification of the tetrad-sterility-causing Solanum stoloniferum cytoplasm in interspecific hybrids with S. tuberosum
Authors: Sanetomo Rena , Nashiki Akito 
Published: March 2021

Abstract
Tetrad sterility, in which only clumps of four premature pollen grains are released from anthers, has been observed in some modern potato cultivars. It is a form of cytoplasmic male sterility caused by the cytoplasm derived from the Mexican tetraploid species Solanum stoloniferum Schlechtd. et Bché., an important source of resistance to Potato virus Y in potato breeding. However, since S. stoloniferum is highly polymorphic, the source of tetrad-sterility-causing cytoplasm is unknown among diverse S. stoloniferum accessions. In this study, we directly crossed 24 S. stoloniferum accessions with pollen from 4x S. tuberosum and obtained 39 hybrids from 12 accessions. Nineteen hybrids from six accessions showed tetrad sterility, with either D/γ- or W/γ-type cytoplasm, and were triploid, tetraploid, or hexaploid. The W/γ-type cytoplasm was not necessarily associated with tetrad sterility. Sequence comparisons of 17 mitochondrial genes and their intergenic regions revealed a length polymorphism in the intergenic region between rpl5 and rps10, in which an amplified band of 859 bp was associated with tetrad sterility. This specific cytoplasm causing tetrad sterility is named TSCsto. The 859-bp band would be a useful diagnostic marker for identifying TSCsto in potato breeding.
Fram Strait: Possible key to saving Arctic ice
Authors: Ivanova Detelina , Bhattacharyya Subarna , Field Leslie , Mlaker Velimir , Strawa Anthony , Player Timothy , Sholtz Alexander 
Published: March 2021

Abstract
We present a modeling study of the sensitivity of present-day Arctic climate dynamics to increases in sea ice albedo in the Fram Strait. Our analysis reveals a new mechanism whereby enhancing the albedo in the Fram Strait triggers a transition of the regional atmospheric dynamics to a negative Arctic Dipole Anomaly phase. This causes an Arctic-wide ice circulation regime, weakening Transpolar Drift and reducing Fram Strait ice export, leading to thickening of the multi-year ice pack. These findings advance our understanding of the key role that the Fram Strait plays in the Arctic climate and highlights a potential path to restoring Arctic sea ice.
Applicability of literature values for Green-Ampt parameters to account for infiltration in hydrodynamic rainfall-runoff simulations in ungauged basins
Authors: Tügel Franziska , Hassan Aziz , Hou Jingming , Hinkelmann Reinhard 
Published: March 2021

Abstract
This study aims to evaluate the suitability of literature parameter values for the Green-Ampt infiltration model to be used in hydrodynamic rainfall-runoff simulations. The outcome of this study supports to decide which literature values should be taken if observed data for model calibration is not available. Different laboratory experiments, a plot-scale experiment in the Thiès catchment in Senegal, and flash floods in the region of El Gouna in Egypt have been simulated with the 2D shallow water model Hydroinformatics Modeling System (hms) incorporating the Green-Ampt model. For four test cases with available runoff data, the results of the calibrated models were compared to those obtained from average values after Rawls et al. [54] and Innovyze [27]. The results showed a clear underestimation of infiltration in two of three considered laboratory experiments, while for a field experiment in Senegal, average values after Rawls et al. [54] led to a strong overestimation and the ones after Innovyze [27] to an underestimation of infiltration. In a case study on flash floods in an ungauged region in Egypt, the values of both sources led to a strong overestimation of infiltration, when the simulation results are compared to observed flooding areas. It can be concluded, that the values after Innovyze [27] lead to overall better results than the ones after Rawls et al. [54]. According to the results, the hydraulic conductivity in ungauged areas with bare sandy soil should be reduced by about 90–100 % compared to the value after Rawls et al. [54].
Identification of Microplastics in Conventional Drinking Water Treatment Plants in Tehran, Iran
Authors: Adib Danial , Mafigholami Roya , Tabeshkia Hossein 
Published: March 2021

Abstract
The presence of microplastics (MPs), as an emerging pollutant is a growing concern in different water resources. These particles are recognized as less than 5 mm in size. Most of the studies have been carried out in surface waters and wastewater treatment plants (WWTPs), but there are few studies on MPs in drinking water treatment plants (DWTPs). This study investigates these particles in three different conventional DWTPs in the city of Tehran, Iran and aims to analyze these particles down to the size of 1 µm. A scanning electron microscope (SEM) was utilized in this study to quantitatively analyze MPs. Accordingly, the average abundance of MPs in raw and treated water samples varied from 1996±268 to 2808±80 MPs L-1 and 971±103 to 1401±86 MPs L-1, respectively. While particles smaller than 10 µm comprised 65-87% of MPs. Moreover, µ-Raman spectroscopy was used to characterize MPs. As the results, polypropylene (PP), polyethylene terephthalate (PET), and polyethylene (PE) were the most abundant identified polymers among MPs comprising more than 53% of particles. Additionally, MPs were categorized as fibers, fragments and spheres. This study fills the knowledge gap of MPs presence in Tehran DWTPs which is of high importance since they supply drinking water for more than 8 million people and investigates the performance of conventional DWTPs in removing MPs.
The importance of diversified physical activities in early childhood for later fundamental movement skills and physical activity level: a seven-year longitudinal study
Authors: Melby Paulina S. , Elsborg Peter , Nielsen Glen , Lima Rodrigo A. , Bentsen Peter , Andersen Lars B. 
Published: March 2021

Abstract
Background: Research indicates that childhood fundamental movement skills (FMS) can predict physical activity (PA) later in life and it has been argued that frequently engaging in a wide diversity of physical activities will eventually improve children’s FMS. However, no longitudinal or experimental studies have confirmed this hypothesis. The aims of this study are to investigate the longitudinal associations between diversified physical activities at age six and later FMS and PA (age nine and 13). Furthermore, we explore to what extent the longitudinal association between diversified physical activity and PA is mediated by FMS.Methods: Longitudinal data from the Copenhagen School Intervention Studywere used for this analysis, where 704 participated (69% response rate). Diversified physical activity (self-reported), FMS (The Körperkoordinationstest für Kinder battery of postural stability and locomotor skills) and PA (accelerometer) were assessed in the children at age six, age nine and age 13. A total of 991 participated in at least one of the measure years. Two structural equation models were constructed, with diversified physical activity at age six and FMS and PA at age nine as predictors of PA and FMS at age 13. Results: The data from both models demonstrated good model fit. Diversified physical activity at six years of age was significantly associated with physical activity and FMS at age 13, when adjusting for sex, age, intervention, weight, height, and previous levels of PA and FMS. Diversified physical activity at age six was also positively associated with PA and FMS at age nine, which were, in turn, positively related to PA at age 13 but to a lesser degree than diversified PA at age six. The association between diversified physical activity at age six and PA at age 13 was not mediated by FMS at age nine. Conclusions: The results of this study indicate that diversified physical activity at age six is important for the development of FMS and PA in adolescence. Increasing the diversity of children’s daily physical activities, not only the amount and intensity, seems important for future PA behavior and thereby health promotion in a life course perspective.
The Relationship Between Intralobar Pulmonary Sequestration and Type a Aortic Dissection: A Case Report
Authors: Lin Gang-Hua , Chen Ying Yi 
Published: March 2021

Abstract
Background: Pulmonary sequestrations often lead to serious complications such as infections, tuberculosis, fatal hemoptysis, cardiovascular problems, and even malignant degeneration, but it is rarely documented with medium and large vessel vasculitis, which is likely to result in acute aortic syndromes.Case presentation: A 44-year-old man with a history of acute Stanford type A aortic dissection status post-reconstructive surgery five years ago. The contrast-enhanced computed tomography (CT) of the chest at that time had also revealed an intralobar pulmonary sequestration in the left lower lung region, and the angiography also presented perivascular changes with mild mural thickening and wall enhancement, which indicated mild vasculitis. The intralobar pulmonary sequestration in the left lower lung region was long-term unprocessed, which was probably associated with his intermittent chest tightness since no specific medical findings were detected but only positive sputum culture with mycobacterium avium-intracellulare complex and Aspergillus. We performed uniportal video-assisted thoracoscopic surgery with wedge resection of the left lower lung. Hypervascularity over the parietal pleura, engorgement of the bronchus due to a moderate amount of mucus, and firm adhesion of the lesion to the thoracic aorta were histopathologically noticed.Conclusion: We hypothesized that a long-term pulmonary sequestration-related bacterial and fungal infection can result in focal infectious aortitis gradually, which may threateningly contribute to aortic dissection.