bluuebunny/crossref_metadata_2025_split huggingface dataset:
New Biomarkers of Kawasaki Disease Identified by Gingival Crevicular Fluid Proteomics
Authors: Fan Xue , Li Ying , Guo Xin , Lan Jingjing , Xu Mingguo 
Published: November 2021

Abstract
Background: Kawasaki Disease (KD) is an acute self-limiting systemic vasculitis syndrome which can result in arterial damage especially in coronary artery. To find possible new biomarkers for the diagnosis of KD by Data independent acquisition (DIA) quantitative proteomics.Methods: Twenty-seven patients with KD were enrolled in the present study, further, gingival crevicular fluid of before IVIG treatment with KD was collected as the experimental group. Meanwhile, 18 healthy volunteers were recruited as the control group.DIA quantitative proteomics mass spectrometry analysis was performed on the GCF samples of each group, and the protein expression profiles of the two groups of GCF were detected. Function enrichment of DEP by KEGG and GO, protein-protein interaction (PPI) analysis for all the DEPs detected, Finally, the multiple reaction monitoring mass spectrometry method was used to verify the selected DEPs.Results:197 DEPs (174 up-regulated and 23 down-regulated) were detected in the CGF between the KD group and the normal control group. Cellular process and metabolic process, binding and catalytic activity are the most altered biological process and molecular function, respectively. NOD−like receptor signaling pathway, Protein processing in endoplasmic reticulum pathway and influenza pathway are most significant pathway. EIF2AK2, B2M and GBP1 are kernel proteins in PPI network. The results of MRM-MS of 12 DEPs including IFIT3, UB2L6, HP, A1AT, HSP90AA1, HNRPC, HSP90AB1, SAA1, MX1, B2M, FKBP4 and TRAP1 were highly consistent with DIA.Conclusions: We suggested that 12 proteins in GCF could be used as new biomarkers for early diagnosis of KD. We also found that KD is closely related to gingival inflammation at the molecular level, which provides new ideas and directions for the diagnosis and treatment of KD.
Space-Temporary Analysis of External Geodynamic Disasters Occurred in Huaraz Province, Ancash - Peru
Authors: Malca Ulises Francisco Giraldo , Joaquin Haniel Josue Torres , Tello Yeni Lucero Torres , Quispe Nicole Dalia Reyes 
Published: November 2021

Abstract
The natural disasters generated by external geodynamics are geological risks that constantly modify landscapes, with a more significant occurrence in mountainous areas, affecting populations and registering many victims in densely populated places. This research analyzes the events in Huaraz province, of Ancash department, in the central Andes of Peru, to find relationships between their occurrence and geographical factors such as altitude, slopes, climate, and extreme meteorological events. An inventory of events was made and classified as floods, mass gravitational movements, waterlogging or snow avalanches. Using QGIS software, spreadsheets and digital elevation models, information on natural disasters, altitude levels, physiography, river basins, meteorological data, and earthquakes were analyzed. As a result, it was obtained that the Quechua region registered 60% of all events; the Santa River basin 76%; the wet season of the Peruvian Andes 78%; and places with slopes between 8% and 50% (wavy relief) 72% of disasters. It is concluded that the best conditions for these events are the intense rainfall and the undulating reliefs, predominant in the Quechua region. Likewise, floods are the disasters that register the most significant number and generate the most damage in Huaraz province. Finally, it was determined that high-intensity El Niño-Southern Oscillation processes do not necessarily increase the number of events for the study area.
Physiological Attributes and Transcriptomics Analysis Reveal the Response Mechanism of Helictotrichon Virescens to Low-Temperature Stress
Authors: Cheng Mingjun , Zheng Mingmin , Cui Kuoshu , Zhang Ruizhen , Yang Tao , Li Xiaofeng , Yan Donghai , Yao Mingjiu , Luo Xuan , Iqbal Muhammad Zafar , Zheng Junjun , He Ruyu , Zhou Qingping 
Published: November 2021

Abstract
Background: Helictotrichon Virescens is a perennial herb mainly distributed in high altitude areas of 2000 ~ 4500 m. It is widely cultivated in the Qinghai-Tibet Plateau of China, strongly resistant to cold, and an essential part of wild herbage in this region. However, the molecular mechanism of Helictotrichon virescens response to low-temperature stress is unclear, and the key regulating genes to specific biological processes are poorly known. Results: It was used physiological and transcriptome analysis to study the cold stress response mechanism in Helictotrichon Virescens. Under low-temperature treatment at 0℃, the leaves reduced chlorophyll content and light energy absorption through light antenna complex (LHCs). As the content of chlorophyll, a and b decreased, as evident were the photoprotection effects. Besides, circadian pathway-plant is crucial for the response to cold stress in Helictotrichon Virescens. Among them, DEG encoding LHY and HY5 showed strongly up-regulated expression during cold stress in Helictotrichon Virescens. Conclusions: This study provides an opportunity to fully understand the response process of Helictotrichon Virescens to low-temperature stress. It answers the pertinent questions in perennial herbaceous cold stress research, how leaves integrate light and low-temperature signals to regulate circadian rhythms in crops, and how leaf tissue reduces light absorption and enhances light protection through optical antenna complex (LHCs).
Men and Women With First Episode Psychosis Present Distinct Profiles of Social Cognition and Metacognition
Authors: Ferrer-Quintero Marta , Fernández Daniel , López-Carrilero Raquel , Birulés Irene , Barajas Ana , Lorente-Rovira Esther , Luengo Ana , Díaz-Cutraro Luciana , Verdaguer Marina , García-Mieres Helena , Gutiérrez-Zotes Alfonso , Grasa Eva , Pousa Esther , Huerta-Ramos Elena , Pélaez Trinidad , Barrigón Maria Luisa , Gómez-Benito Juana , González-Higueras Fermín , Ruiz-Delgado Isabel , Cid Jordi , Moritz Steffen , Sevilla-Llewellyn-Jones Julia , Ochoa Susana 
Published: November 2021

Abstract
Deficits in social cognition and metacognition impact the course of psychosis. Gender differences in social cognition and metacognition could explain heterogeneity in psychosis. 174 (58 females) patients with first-episode psychosis completed a clinical, neuropsychological, social cognitive and metacognitive assessment. Subsequent latent profile analysis split by gender yielded 2 clusters common to both genders, a specific male profile characterized by presenting jumping to conclusions and a specific female profile characterized by cognitive biases. Males and females in the homogeneous profile seem to have a more benign course of illness. Males with jumping to conclusions had more clinical symptoms and more neuropsychological deficits. Females with cognitive biases were younger and had less self-esteem. These results suggest that males and females may benefit from specific targeted treatment and highlights the need to consider gender when planning interventions.
The Catalytic Activity of GSTM1 In vitro is Independent of MAPK8
Authors: Robin Shannon , Ben Hassine Khalil , Mlakar Simona Jurkovic , Mlakar Vid , Ansari Marc , Uppugunduri Chakradhara Rao S. 
Published: November 2021

Background:
Glutathione S-transferases (GSTs) are phase II metabolic enzymes crucial
for the metabolism of electrophilic drugs. Additionally, several GST isoforms are involved in protein-
protein interaction with mitogen-activated protein kinases (MAPKs), modulating apoptosis
pathways.

Methods:
To assess the potential change of enzymatic activity, we performed a GST enzyme assay
with human recombinant GSTM1 in the presence and absence of MAPK8. Recently, GSTM1 has
been demonstrated to interact with MAPK8 both in silico and in vitro. The binding interface predicted
in silico comprised amino acid residues present on the surface of the protein and a few were
deep in the active site of the protein.

Results:
The experiment demonstrated that the GSTM1 activity was conserved even in the presence
of MAPK8 in the assay.

Conclusion:
The possible alteration in the activity of MAPK8 in this interaction needs to be evaluated
in further experiments.
Exploring the Representation of History and 'Slow Violence' in "Philadelphia Fire" and "The Lone Ranger and Tonto Fistfight in Heaven"
Authors: Orr Alice F. 
Published: November 2021

After connecting history to urban spatiality in Teju Cole's Open City, this paper develops Rob Nixon's articulation of "slow violence" to demonstrate how John Edgar Wideman and Sherman Alexie's novels depict issues of authenticity in storytelling, highlighting the limitations of representing the effects of “slow violence” on the cultural, physical, and economic welfare of marginalised communities in the aftermath of major violent events.
ITERATIVE COMPUTATION FOR SOLVING CONVEX OPTIMIZATION PROBLEMS OVER THE SET OF COMMON FIXED POINTS OF QUASI-NONEXPANSIVE AND DEMICONTRACTIVE MAPPINGS
Authors: Sow Thierno M. M. 
Published: November 2021

In this paper, a new iterative method for solving convex minimization problems over the set of common fixed points of quasi-nonexpansive and demicontractive mappings is constructed. Convergence theorems are also proved in Hilbert spaces without any compactness assumption. As an application, we shall utilize our results to solve quadratic optimization problems involving bounded linear operator. Our theorems are significant improvements on several important recent results.
ON GENERALIZED RELATIVE COMMUTATIVITY DEGREE OF FINITE MOUFANG LOOP
Authors: Hasanzadeh Hamideh , Iranmanesh Ali , Azizi Behnam 
Published: November 2021

For a given element $g$ of a finite group $G$, the probablility that the commutator of randomly choosen pair elements in $G$ equals $g$ is the relative commutativity degree of $g$. In this paper we are interested in studying the relative commutativity degree of the Dihedral group of order $2n$ and the Quaternion group of order $2^{n}$ for any $n\geq 3$ and we examine the relative commutativity degree of infinite class of the Moufang Loops of Chein type, $M(G,2)$.
THE EFFECT OF WASTE MANAGEMENT ON THE ISLAMIC WORK ETHIC OF MADIUN COMMUNITY
Authors: Kamaluddin Imam , Yunita Wulandari Yunita , Arief Suyoto , Zarkasyi Muhammad Ridlo 
Published: November 2021

Work ethic isÂ crucial to the growthÂ of human life. Related to the problem of waste, humans must be able to position themselves with waste around it.Â As a result,Â this study will discuss a relationship between one's Islamic work ethic and the form of a Waste Bank in the surrounding area, in order to improveÂ the community's Islamic work ethic.Â TheÂ studyÂ is a survey research with a quantitative descriptive approach with primary data obtained from questionnaires distributed to Waste BankÂ customers.Â Researchers want to know the influenceÂ of the Waste BankÂ on improvingÂ Islamic work ethic ofÂ Madiun community.Â The analysis results show that the value of t-count is greater than the value of t-table (11,788> 1,97612) between the variables Waste Bank (X) and Islamic Work Ethic (Y), indicating that H0 was rejected and Ha was accepted.Â Thus there is an influence on the existence of a waste bank to increase the Islamic work ethic of the MadiunÂ community. While the amount of influence is 48.4% and 51.6% is influenced by other variables outside the research.
Analysis of Savings and Loans Scheme by Family Welfare Empowerment Organization As a Fulfillment Solution for Muslim in the Pandemic Outbreak
Authors: Aisyiah Helti Nur , Yahya Alvin 
Published: November 2021

This study aims to analyze the savings and loans scheme at the Family Welfare Empowerment Organization (FWEO) at the Neighborhood Association (NA) XY, Karanganyar Regency, during the Covid-19 pandemic outbreak. This study uses a qualitative approach with the method of observation and interviews. Observations observe the object of research when transacting savings and loans and the distribution of residual income. Interviews confirmed people who are directly related to the savings and loans activities at FWEO of NA XY including the chairperson, fund administrator of FWEO and Muslim borrowers.The results of the study show that the savings and loans activities at FWEO of NA XY are family-based community activities and prioritize the principle ofÂ ta'awunÂ or mutual assistance. One of the assistance is given to Muslims members of FWEO and suffering from financial difficulties during the pandemic outbreak. The principle ofÂ ta'awunÂ is reflected by the scheme of savings, loans and the ease use of residual income and based on trust among members. This fact supports the findings that the existence of FWEO in NA XY makes it easier for Muslims to obtain funds as well as to ease the economic burden, especially for those affected by Covid-19.
FEATURES OF SURGICAL TREATMENT OF SPINAL DYSRAPHISM OF THE SACRALCOCCYGEAL AREA OF INFANTS
Authors: O. B. Bodnar  , A. I. Roshka  
Published: November 2021

Spinal dysraphism (SD) of children is a complicated and unsolved problem in pediatric neurosurgery. Pathology of sacral-coccygeal area is 30 % - 50 % of the total number of SD of children. The presence of a large number of nearest complications (wound abscess, meningitis, the gap of the wounds, liquorrhoea) and long-term postoperative period complications (impaired functions of the lower limbs and pelvic organs) are the basis to search for improved methods of treatment. 19 newborns with SD sacral-coccygeal area were operated. 16 children were aged 1 to 10 days and 3 from 11 to 28 days. Depending on the anatomical variants of SD sacral-coccygeal areas they were divided into: meningocele (26,32%); myelomeningoradiculocele (15,78%); myelomeningocele (31,58%). All surgery was performed with the use of microsurgical tools and microsurgical techniques under optical multiplication using electric coagulator for the tissue (EC-300M 1). A favourable condition for better results in the treatment of SD was selection of the optimal timing and techniques of surgery. The best results for surgery were the age of 7 to 10 days (12 children). The term of surgery from 11 until 28 days for 3 children was due to the presence of hernia infection and purulence, which required the implementation of preoperative preparation for 5-7 days. The approach was determined by: hernia localization, size and spine defect, the degree of subcutaneous tissue development, the condition of hernia layers, displacement and plasticity of the back tissues. The disadvantage of all methods of surgical treatment of SD there is a danger of iatrogenic damage to neural elements during surgery, depending on the quality of its performance. While performing surgical treatment of SD microsurgical radiculolysis with precision microsurgical excision of all cicatricial adhesions, cerebrospinal fluid cysts and other intraradicular formations, and thorough revision of the spinal canal should be undertaken. Dysfunction of the pelvic organs (urine and anal incontinence) and lower limbs are observed in 63,16% of children operated on for SD in the neonatal period that requires further development of methods of their surgical correction at a later age.
PENGARUH ARTIFICIAL INTELLIGENCE TERHADAP CUSTOMER EXPERIENCE (STUDI PADA PENGGUNA GOJEK BANDUNG, JAWA BARAT)
Authors: Arviollisa Putri Ayunda Dipta , Chan Arianis , Nirmalasari Healthy 
Published: November 2021

Artificial Intelligence (AI) allows marketers to differentiate their consumers into different personas and understand what motivates consumers in purchasing decisions so that marketers use AI to identify and predict consumer behavior, and through this information marketers are able to build unique experiences for consumers. This study tests and measures the effect of AI on customer experience by using simple regression analysis with four dimensions of AI: mechanical intelligence, analytical intelligence, intuitive intelligence and empathetic intelligence on the four dimensions of customer experience: immersion, flow, cognitive fit and emotional fit with a four-point Likert scale. Based on the results of study on 116 respondents, it it known that both AI and Gojek's customer experience are good and there is a significant effect of AI on customer experience. Artificial Intelligence (AI) memungkinkan pemasar untuk membedakan konsumennya menjadi persona yang berbeda dan memahami apa yang memotivasi konsumen dalam keputusan pembelian sehingga pemasar menggunakan AI untuk mengidentifikasi dan memprediksi perilaku konsumen, dan melalui informasi ini pemasar mampu membangun pengalaman unik bagi konsumen. Penelitian ini bertujuan untuk menguji dan mengukur pengaruh AI terhadap customer experience dengan menggunakan analisis regresi sederhana dengan empat dimensi AI: mechanical intelligence, analytical intelligence, intuitive intelligence dan empathetic intelligence terhadap empat dimensi customer experience: immersion, flow, cognitive fit dan emotional fit dengan skala Likert empat poin. Berdasarkan hasil penelitian terhadap 116 responden, didapatkan bahwa baik AI maupun customer experience Gojek dinilai baik dan terdapat pengaruh yang signifikan AI terhadap customer experience.
Pengaruh Inovasi, Kepercayaan Diri Dan Pengambilan Risiko Terhadap Intensi Berwirausaha Pada Mahasiswa Universitas Tarumanagara
Authors: Nathasia Nathasia , Rodhiah Rodhiah 
Published: November 2021

The purpose of this study was to determine the effect of innovation, self-confidence, and risk taking on entrepreneurial intentions. The sample was chosen using nonprobability sampling technique with a number of 100 respondents from Tarumangara University students. The questionnaire was distributed using Google Form and analyzed using the SmartPLS 3.0 program. Individually and as a whole, the results of this study indicate that innovation, self-confidence, and risk taking have a positive effect on entrepreneurial intentions. This means that in entrepreneurial intentions are needed which is innovation, confidence, and risk taking. Tujuan penelitian ini adalah untuk mengetahui pengaruh inovasi, kepercayaan diri, dan pengambilan risiko terhadap intensi berwirausaha. Sampel dipilih menggunakan teknik nonprobability sampling dengan jumlah 100 responden mahasiswa Universitas Tarumangara. Kuesioner disebar menggunakan google form dan dianalisis dengan menggunakan program SmartPLS 3.0. Secara individu dan keseluruhan, hasil penelitian ini menunjukkan bahwa inovasi, kepercayaan diri, dan pengambilan risiko berpengaruh positif terhadap intensi berwirausaha. Artinya dalam intensi berwirausaha dibutuhkan antara lain inovasi, kepercayaan diri, dan pengambilan risiko.
Pengaruh Pendidikan Kewirausahaan, Efikasi Diri Dan Locus Of Control Terhadap Intensi Berwirausaha
Authors: Blegur Anastasia , Handoyo Sarwo Edy 
Published: November 2021

The purpose of this research is to determine the effect of entrepreneurship education, self-efficacy and locus of control on entrepreneurial intentions of Tarumanagara University Faculty of Economics students. This study uses a non-probability sampling method with the number of samples taken in the study were 150 respondents of the Faculty of Economics students at Tarumanagara University. This questionnaire was distributed to respondents from the Economics department who had taken entrepreneurship courses. Data analysis method uses SEM (Structural Equation Modeling) with the SmartPLS program. The results of this study indicate that there is an influence of entrepreneurship education, self efficacy and locus of control on entrepreneurial intentions of Tarumanagara University Faculty of Economics students. Tujuan penelitian ini adalah untuk mengetahui pengaruh pendidikan kewirausahaan, efikasi diri dan locus of control terhadap intensi berwirausaha mahasiswa Fakultas Ekonomi Universitas Tarumanagara. Penelitian ini menggunakan metode pengambilan sampel non-probability sampling dengan jumlah sampel yang diambil dalam penelitian ialah 150 responden mahasiswa Fakultas Ekonomi Universitas Tarumanagara. Kuesioner ini dibagikan kepada responden jurusan Ekonomi yang sudah mengambil mata kuliah kewirausahaan. Metode analisis data menggunakan SEM (Structural Equation Modelling) dengan program SmartPLS. Hasil penelitian ini menunjukan bahwa terdapat pengaruh pendidikan kewirausahaan, efikasi diri dan locus of control terhadap intensi berwirausaha mahasiswa Fakultas Ekonomi Universitas Tarumanagara.
Pengaruh Technology Usage, E- Networking Dan Government Support Terhadap Keberhasilan Entrepreneur Di Jakarta
Authors: Livia Livia , Nuringsih Kartika 
Published: November 2021

The purpose of this study is to examine the effect of technology usage, e- networking and government support to entrepreneur success in Jakarta. The sample as selected by a nonprobability sampling method of 100 respondens. The results of this study indicate that on technology usage, e –networking does not significantly influence the success of entrepreneurs in Jakarta and there is a significant on government support influence on the success of entrepreneurs in Jakarta. Tujuan dari penelitian ini adalah untuk menguji pengaruh technology usage, enetworking dan government support terhadap keberhasilan entrepreneur di Jakarta. Sampel dipilih menggunakan metode nonprobability sampling sebesar 100 responden. Hasil penelitian ini menunjukan bahwa pada technology usage dan e-networking tidak berpengaruh secara signifikan terhadap keberhasilan entrepreneur di Jakarta dan terdapat pengaruh yang signifikan pada government support terhadap keberhasilan entrepreneur di Jakarta
Pengaruh Motivasi, Kepuasan Kerja, Dan Disiplin Kerja Terhadap Kinerja Karyawan
Authors: Sandika Sandika , Andani Kurniati W. 
Published: November 2021

The purpose of this study was to find out and analyze the influence of motivation, job satisfaction and work discipline on employee performance at PT Aneka Warna Semesta Pratama. This research was conducted by non-random sampling method with the type of convenience sampling. The researcher distributed questionnaires to 52 employees of PT Aneka Warna Semesta Pratama. Data analysis using PLS SEM analysis. The results of the analysis concluded that motivation, job satisfaction and work discipline influence the employee performance of PT Aneka Warna Semesta Pratama. Tujuan penelitian ini adalah untuk mengetahui dan menganalisa pengaruh motivasi, kepuasan kerja dan disiplin kerja terhadap kinerja karyawan di PT Aneka Warna Semesta Pratama. Penelitian ini dilakukan dengan metode non-random sampling dengan jenis convenience sampling. Peneliti menyebarkan kuesioner kepada 52 karyawan PT Aneka Warna Semesta Pratama. Analsisi data menggunakan analisis SEM PLS. Hasil analisis menyimpulkan bahwa motivasi, kepuasan kerja dan disiplin kerja berpengaruh terhadap kinerja karyawan PT Aneka Warna Semesta Pratama.