bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identifying the Subtypes and Characteristics of Mental Workload Among Chinese Physicians in Outpatient Practice: A Latent Profile Analysis
Authors: Li Dehe , Hu Yinhuan , Chen Hao , Zhu Ximin , Wu Xiaoyue , Li Jiayi , Zhang Zemiao , Liu Sha 
Published: November 2021

Objective: The purpose of this study is to investigate the mental workload level of physicians in outpatient practice since the normalization of prevention and control of the COVID-19 pandemic in China and explore the subtypes of physicians regarding their mental workload.Methods: A cross-sectional survey of 1,934 physicians primarily in 24 hospitals in 6 provinces in Eastern, Central, and Western China was conducted from November 2020 to February 2021. A latent profile analysis was performed to identify clusters based on the six subscales of the Chinese version of physician mental workload scale developed by our research team. Chi-square tests were performed to explore the differences in demographic characteristics of the subtypes among the subgroups, and multinomial logistic regression analysis was further conducted to identify the determinants of the subtypes of physicians.Results: Overall, the participating physicians reported high levels of task load but with high self-assessed performance (68.01 ± 14.25) while performing communication work tasks characterized by direct patient interaction in outpatient clinics. About 33.8% of the participating physicians were identified as “high workload and high self-assessment” subtype, compared to 49.7% “medium workload and medium self-assessment” subtype and 16.4% “low workload and low self-assessment” subtype. Physicians in “high workload and high self-assessment” subtype had the highest mean mental workload score. Physicians who were female, younger, married, worse health status, those who had lower educational level and an average monthly income of 5,001–10,000 RMB, those who worked in tertiary A hospitals, more hours per week and more than 40 h per week in outpatient clinics, and those who saw more outpatients per day, and spent more time per patient but with higher outpatient satisfaction were more likely to belong to “high workload and high self-assessment” subtype.Conclusion: Our findings can help provide a solid foundation for developing targeted interventions for individual differences across physicians regarding their mental workload. We suggest the hospital managers should pay more attention to those physicians with characteristics of the “high workload and high self-assessment” subtype and strengthen the management of the workload of this subtype of physicians to reduce the risks of their mental health, and to maintain their high work performance in outpatient clinics.
Practical Recommendations for the Preoperative Screening and Protective Protocols in Cancer Surgeries During COVID-19: A Systematic Review
Authors: Dorri Sara , Sari Fateme , Seyedhasani Seyedeh Nahid , Atashi Alireza , Hashemi Esmatalsadat , Olfatbakhsh Asiie 
Published: November 2021

Introduction: The new coronavirus (COVID-19) has posed many new challenges to the health care and the timing of surgical care. At the beginning of the pandemic many guidelines recommended postponing elective surgical procedures to reallocate resources. As regards, delay in cancer treatment could be effective on cancer progression. The aim of this systematic review was to outline a guideline for preoperative screening before cancer surgeries and protecting health care workers during the pandemic.Materials and Methods: This study was conducted through a search in electronic databases up to August 2020. PubMed, EMBASE, Web of Science, Scopus, Science Direct, and Google Scholar databases were searched without time limitation. The keywords were a combination of preoperative, cancer surgery, COVID-19, and their synonyms.Results: The most commonly used ways to triage preoperatively were telephone pre-assessment for suspicious symptoms and history of contact or travel, 14-day self-isolation, in- hospital queries at admission, temperature monitoring, and isolation in a single room COVID-free ward or physical distancing. Reverse transcription-polymerase chain reaction (RT-PCR) test 24–72 h before operation was recommended commonly, except in inaccessible centers, but non-contrast chest-CT scan is not routinely advised for elective surgeries to salvage medical resources. Recommended personal protective equipment (PPE) for staffs were wearing N95 mask in addition to gown, gloves, eye protection in aerosol-generating procedures (AGPs), and wearing gloves, hats, and disposable surgical masks, practice distancing, and hand hygiene for all staffs. Meanwhile team separation of hospital staffs caring for COVID-19 patients, segregated areas for COVID-19 clean and contact, restriction of visitors and family members, and personal distancing are mostly recommended.Conclusion: We hope this review would be a guidance for triage, preoperative testing, and summarizing safety principles during COVID-19 pandemic alongside with surgical reintegration.
Hand-Assisted Laparoscopic Surgery Is Superior to Open Liver Resection for Colorectal Liver Metastases in the Posterosuperior Segments
Authors: Abu-Zaydeh Omar , Sawaied Muneer , Berger Yael , Mahamid Ahmad , Goldberg Natalia , Sadot Eran , Haddad Riad 
Published: November 2021

Introduction: Laparoscopic liver resections (LLR) of colorectal metastasis located in posterosuperior segments (1, 4A, 7 and 8) are challenging and highly demanding. The aim of our study is to determine the safety and feasibility of hand-assisted laparoscopic surgery (HALS) in the resections of the posterosuperior lesions and to compare the peri-operative, short-term and long-term outcomes with the open liver resection (OLR) approach.Methods and Results: A retrospective study of patients who underwent either HALS or OLR for metastatic colorectal cancer (mCRC) located in the posterosuperior segments of the liver between 2008 and 2018 in two university affiliated medical centers.Results: A total of 187 patients were identified, of whom 78 underwent HALS and 109 underwent OLR. There was no difference between the HALS and OLR with regard to preoperative factors (age, primary CRC tumor location, number and anatomical distribution of liver metastasis, pre-operative neo-adjuvant treatment, operative time, blood transfusion rate, and resection margins positivity). On the other hand, HALS compared to OLR had a significantly shorter mean hospital stay (4 vs. 6 days; P = 0.003), and a lower total complications rate (25 vs. 47% P = 0.006). Both groups had no 30-day mortality. Also, patients who underwent HALS vs. OLR had similar liver metastases recurrence (55 vs. 51%. P = 0.65) and 5-year survival (47 vs. 45%. P = 0.72).Conclusions: HALS for mCRC located in posterosuperior liver segments is safe and feasible and it is a preferable approach due to its lower complication rate and shorter hospital stay while not compromising survival and disease recurrence.
Evaluation of Carbon Nanoparticle Suspension and Methylene Blue Localization for Preoperative Localization of Nonpalpable Breast Lesions: A Comparative Study
Authors: Zhou Yeqing , Liang Yiran , Zhang Jianshu , Feng Yang , Li Xiaoyan , Kong Xiaoli , Ma Tingting , Jiang Liyu , Yang Qifeng 
Published: November 2021

Background: The resection of nonpalpable breast lesions (NPBLs) largely depends on the preoperative localization technology. Although several techniques have been used for the guidance of NPBL resection, more comfortable and effective methods are needed. This aim of this study was to evaluate the use and feasibility of carbon nanoparticle suspension (CNS) and methylene blue (MB)-guided resection of NPBL, to introduce alternative techniques.Methods: A total of 105 patients with 172 NPBLs detected by breast ultrasound were randomized to CNS localization (CNSL) group and MB localization (MBL) group. The injection times of the two groups were divided into 2, 4, 6, 12, 16, and 20 h before surgery. In this study, localization time, stained area, operation time, total resection volume (TRV), calculated resection ratio (CRR), and pathological diagnosis were assessed.Results: All of the 172 lesions were finally confirmed benign. Dye persisted in all cases in the CNSL group (109/109, 100%), while that persisted in only 53 cases in the MBL group (53/63, 84.1%) (P &lt; 0.001). There was a significant correlation between dyeing time and dyeing area in the MBL group (r = −0.767, P &lt; 0.001); however, there was no significant correlation in the CNSL group (r = −0.154, P = 0.110). The operation time was 11.05 ± 3.40 min in the CNSL group and 13.48 ± 6.22 min in the MBL group (P &lt; 0.001). The TRV was 2.51 ± 2.42 cm3 in the CNSL group and 3.69 ± 3.24 cm3 in the MBL group (P = 0.016). For CRR, the CNSL group was lower than the MBL group (7.62 ± 0.49 vs. 21.93 ± 78.00, P = 0.018). There is no dye remained on the skin in the MBL group; however, dye persisted in 12 patients (19.4%) in the CNSL group (P = 0.001).Conclusion: Carbon nanoparticle suspension localization and MBL are technically applicable and clinically acceptable procedures for intraoperatively localizing NPBL. Moreover, given the advantages of CNSL compared to MBL, including the ability to perform this technique 5 days before operation and smaller resection volume, it seems to be a more attractive alternative to be used in intraoperative localization of NPBL.
Decrease in ITGA7 Levels Is Associated with an Increase in α-Synuclein Levels in an MPTP-Induced Parkinson’s Disease Mouse Model and SH-SY5Y Cells
Authors: Han Sangeun , Seo Min Hyung , Lim Sabina , Yeo Sujung 
Published: November 2021

We investigated the potential association between integrin α7 (ITGA7) and alpha-synuclein (α-syn) in a methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson’s disease (PD) mouse model. Tyrosine hydroxylase (TH), ITGA7, and α-syn expression in the substantia nigra (SN) of the brain were observed to examine the pathological characteristics of PD. To determine the relationship between ITGA7 and PD, the expression of TH and α-syn was investigated after ITGA7 siRNA knockdown in SH-SY5Y cells. The ITGA7 microarray signal was decreased in the SN of the MPTP group, indicating reduced ITGA7 expression compared to that in the control. The expression patterns of ITGA7 in the control group and those of α-syn in the MPTP group were similar on immunohistochemical staining. Reduction in ITGA7 expression by ITGA7 siRNA administration induced a decrease in TH expression and an increase in α-syn expression in SH-SY5Y cells. The decreased expression of ITGA7 significantly decreased the expression of bcl2 and increased the bax/bcl2 ratio in SH-SY5Y cells. These results suggest that reduced ITGA7 expression may be related to increased α-syn expression and apoptosis of dopaminergic cells in an MPTP-induced PD mouse model. To the best of our knowledge, this is the first study to show an association between ITGA7 and PD.
Pengaruh Waktu Proses pada Desalinasi Air Laut dengan Metode Elektrokoagulasi secara Batch
Authors: Ardiansyah Rifki , Putra Triyoga Meiditama , Suminar Dian Ratna , Ngatin Agustinus 
Published: November 2021

ABSTRAK
Salah satu upaya untuk menjaga persediaan air yaitu dengan cara menurunkan parameter air laut agar memenuhi parameter air tawar menggunakan metode elektrokoagulasi. Penelitian ini bertujuan untuk mempelajari pengaruh waktu proses elektrokoagulasi terhadap penurunan TDS, kekeruhan, kadar Cl, dan kadar Fe. Selain itu, untuk mengetahui perbandingan antara elektroda Al dan Fe. Air laut diambil dari Pantai Pelabuhan Ratu. Elektroda yang digunakan adalah Al dan Fe dengan ukuran 15x10 cm2. Tegangan yang digunakan yaitu 5 volt atau rapat arus sebesar 0,137 A/dm2 dengan waktu proses 15, 30, 45, dan 60 menit serta volume bahan bakunya 4 Liter. Penelitian dengan waktu proses 30 menit dan proses pengendapan selama satu hari mampu menurunkan kekeruhan hingga 2,28 NTU (55,07%); TDS hingga 1.010 mg/L (3,71%); kadar Cl hingga 271,98 mg/L (3,52%); dan kadar Fe 0,05 mg/L (40,65%). Proses elektrokoagulasi menggunakan elektroda aluminium lebih baik dibandingkan elektroda besi pada waktu proses 30 menit.

ABSTRACT
One of the efforts to maintain water supply is by lowering seawater parameters to meet freshwater parameters using the electrocoagulation method. This study aims to study the effect of electrocoagulation process time on the decrease in TDS, turbidity, Cl content, and Fe content. In addition, to determine the comparison between Al and Fe electrodes. Seawater is taken from Pelabuhan Ratu Beach. The electrodes used are Al and Fe with a size of 15x10 cm2. The voltage used is 5 volts or a current density of 0,137 A/dm2 with processing times of 15, 30, 45, and 60 minutes and the volume of the raw material is 4 liters. Research with a processing time of 30 minutes and sedimentation for one day was able to reduce turbidity up to 2,28 NTU (55,07%); TDS up to 1.010 mg/L (3,71%); Cl content up to 271,98 mg/L (3,52%); and Fe content of 0,05 mg/L (40,65%). The electrocoagulation process using aluminum electrodes was better than iron electrodes at a processing time of 30 minutes.
PIPAC (Pressurized Intraperitoneal Aerosol Chemotherapy) en el tratamiento de la carcinomatosis peritoneal. Primeros casos en Chile.
Authors: Uribe Maturana Mario , Cereceda González Luis , López Köstner Francisco , García Carrasco Carlos , Guerrero González Marco , Vargas Vargas Victoria 
Published: November 2021

Introducción: PIPAC (Pressurized Intraperitoneal Aerosol Chemotherapy) Es una técnica que, vía laparoscopía, permite administrar quimioterapia en aerosol intraperitoneal, para el tratamiento de la carcinomatosis, ya sea para disminuir masa tumoral y aumentar la resecabilidad, o como paliación sintomática.Objetivo: Presentar los dos primeros casos de PIPAC en Chile, las consideraciones técnicas y revisión de la literatura.Pacientes y Método: Se describe la forma en que un programa PIPAC fue implementado en Clínica Las Condes. Se describe la técnica. Este procedimiento se realizó en dos pacientes, ambas portadoras de carcinomatosis con ascitis refractaria. Resultados: No hubo complicaciones. Alta a las 24 horas. Ambas pacientes presentaron disminución de la ascitis, la que se ha mantenido a los seis meses de seguimiento.Discusión: PIPAC es una técnica emergente, que ha demostrado ser segura, con escasas complicaciones, cuya indicación incluye carcinomatosis por cáncer de colon y ovario y que se está extendiendo a páncreas, vía biliar y estómago. Su rol exacto está por definirse.Conclusiones: PIPAC es una técnica factible de realizar en nuestro país; sus resultados preliminares son alentadores y exentos de complicaciones.
Pengaruh Konsentrasi Urine Sapi dan Perendaman Terhadap Pertumbuhan Setek Jambu Air King Rose (Syzygium aqueum Burn.f.Alston)
Authors: Sudartini Tini , Hartini Elya , Burhan Lulu Sofia 
Published: December 2021

Jambu air diperbanyak dengan setek yang berasal dari hasil pangkasan. Setek perlu dipercepat tumbuhnya denganÂ perendaman dalam Â urine sapi yang mengandung Â ZPT IAA dan IBA. Lama perendaman setek dalam larutan urine sapi disesuaikan dengan konsentrasinya.Â Penelitian bertujuan untuk mengetahui pengaruh konsentrasi urine sapi dan lama perendaman terhadap pertumbuhan setek jambu air king rose apple (Syzygium aqueum Burn.f.Alston). Â Percobaan dilaksanakan di Kelurahan Kahuripan Kecamatan Tawang Kota Tasikmalaya, pada Â bulan Februari sampai April 2020. Penelitian ini menggunakan metode ekperimental, dengan Rancangan Acak Kelompok (RAK) pola faktorial diulang sebanyak dua kali. Faktor pertama adalah konsentrasi urine sapi dengan empat taraf, yaitu ao= tanpa urine sapi ,a1= konsentrasi urine sapi 30%, a2= konsentrasi urine sapi 50%, dan a3= konsentrasi 70%. Faktor kedua adalah lama perendaman dalam urine sapi terdiri dari empat taraf, yaitu p0= kontrol), p1= 60 menit, p2= 90 menit, dan p3= 120 menit. Data dianalisis menggunakan sidik ragam dengan uji F dan dilanjut dengan Uji Jarak Berganda Duncan dengan taraf nyata 5%. Hasil penelitian menunjukkan bahwa terdapat interaksi antara konsentrasi urine sapi dan lama perendaman terhadap jumlah tunas. Perlakuan konsentrasi urine sapi 50% dengan lama perendaman 60 menit menghasilkan jumlah tunas yang paling banyak. Secara mandiri konsentrasi urine sapi 50% menghasilkan panjang tunas terpanjang. Konsntrasi urine sapi dan lama perendaman tidak berpengaruh terhadap kecepatan bertunas, luas daun dan panjang akar.
Pengawasan Profesional Kepala Sekolah Dalam Meningkatan Mutu Pembelajaran
Authors: Marhawati Besse , Sulkifly Sulkifly 
Published: November 2021

Penelitian ini bertujuan untuk mendeskripsikan Pengawasan professional kepala sekolah dalam peningkatan mutu pembelajaran guru yang meliputi: (1) upaya-upaya kepala sekolah membantu guru mengatasi kesulitan mengajarnya dalam menyesuaikan dengan tuntutan perubahan baru di MIM Unggulan Kota Gorontalo; (2) upaya-upaya kepala sekolah dalam melakukan penilaian terhadap sasaran program pengajaran yang disesuaikan dengan kebutuhan belajar peserta didik di MIM UnggulanKota Gorontalo; (3) upaya-upaya kepala sekolah dalam melakukan perbaikan program pengajaran yang telah direncanakan di MIM Unggulan Kota Gorontalo; (4) upaya-upaya kepala sekolah melakukan program-program perubahan di MIM Unggulan Kota Gorontalo; dan (5) upaya-upaya kepala sekolah melakukan evaluasi terhadap program-program pengajaran di MIM Unggulan Kota Gorontalo.Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kualitatif dengan rancangan studi kasus yang berlokasi di MIM Unggulan Kota Gorontalo. Hasil penelitian menunjukkan: (1) upaya-upaya kepala sekolah membantu guru mengatasi kesulitan mengajarnya dalam menyesuaikan dengan tuntutan perubahan baru Di MIM Unggulan Kota Gorontalo meliputi: membantu guru yang mengalami kesulitan mengajar (Menggabungkan ke group, sharing ilmu, penggunaan model, metode, dan teknik pemlelajaran), menyiapkan laptop dan LCD di kelas, penyediaan buku paket, pelatihan pembuatan video-video pembelajaran, mendesain pembelajaran yang menyenangkan, dan penyediaan jaringan listrik dan internet (WIFI) dan Indi Home; (2) upaya-upaya kepala sekolah dalam melakukan penilaian terhadap sasaran program pengajaran yang disesuaikan dengan kebutuhan belajar peserta didik Di MIM Unggulan Kota Gorontalo meliputi: melakukan supervisi administrasi dan supervisi kelas, pemantauan melalui CCTV dan pemantauan langsung ke kelas, bimbingan khusus terhadap siswa-siswa yang memiliki bakat dan potensi untuk persiapan dalam mengikuti lomba; (.3) upaya-upaya kepala sekolah melakukan program-program perubahan di MIM Unggulan Kota Gorontalo meliputi: bimbingan khusus bagi siswa yang orang tuanya ingin mengikutkan anaknya dalam bimbingan di bidang matematika, sains, tilawah, bimbingan khusus juga dilakukan bagi siswa-siswa yang memiliki keinginan sendiri, penilaian karakter siswa; (4) upaya-upaya kepala sekolah melakukan program-program perubahan di MIM Unggulan Kota Gorontalo meliputi: kerjasama dengan sekolah, perguruan tinggi dan lembaga bimbingan belajar, raport digital, kultum setelah sholat Dzuhur, proaktif dalam mengikuti lomba-lomba, penilaian sikap berbasis IT melalui aplikasi Dojo Class, absensi online, group kelas, akun untuk guru, siswa, dan orang tua, dan program hafalan Qur’an juz 30; dan (5) upaya-upaya kepala sekolah melakukan evaluasi terhadap program-program pengajaran di MIM Unggulan Kota Gorontalo meliputi: rapat evaluasi dalam hal ini membahas tentang kendala terhadap program pengajaran yang telah direncanakan, dan kegiatan Problem Solving setiap hari Ju’mat.
Serum ferritin level of transfusion dependent thalassaemia patients- A Single Centre Study
Authors: Islam Khaza Amirul , Baqi Saqi Md. Abdul , Rahman Md. Arif-Ur- , Md. Shafiul Azam  , Sharmin Mahbuba , Kabir Amin Lutful , Akther Tahmina 
Published: November 2021

The aim of the study was to determine serum ferritin level in transfusion dependent thalassaemia patients. A total of 64 transfusion dependent thalassaemia (TDT) patients was included in this cross sectional study from April, 2018 to September, 2019 according to selection criteria. Body iron load was estimated by serum ferritin level. The study sample consisted of 43 male and 21 female TDT patients, with a mean age of 25.5 years. Most of the patients (43.8%) patients had serum ferritin level in between 1000-2500 ng/ml. 12 patients (18.7%) had serum ferritin level >5000 ng/ml and 3 patients (4.7%) had serum ferritin in between 2501-5000 ng/ml. The mean serum ferritin was found 2462.6 ± 2792.7ng/ml with range from 207.0 -11891.2ng/m.
Türkçe ve Almanca Dijital Ortamlarda Kadınların Kullandıkları Hitap İfadeleri
Authors: ÖZTÜRK DAĞABAKAN Fatma 
Published: November 2021

Hitaplar gerek formal konuşmada gerekse informal dilde belirleyici bir özelliğe sahiptir. Hitaplar konuşmaya, yazmaya veya herhangi bir yazılı belgeye başlarken kullanılan ve göndericinin alıcıya yönelik bakış açısını belirten dilsel ifadelerdir. Hitap edilen kişi veya gruplar muhatap olarak adlandırılır.
Selamlama ve hitap araştırmalarında, bir muhataba hitap ederken kullanılan dilsel araçlara hitap biçimleri denir. Dilsel hitap biçimleri, ad ve zamir kategorisine ayrılabilir. Ad kategorisindeki hitap türleri isimlerin, mesleki ve diğer unvanların kullanımını içerir. Hitapların zamir biçimleri kendilerini şahıs zamirlerinde gösterir. Zamirlerin bir alt sınıfı olarak, şahıs zamirleri gönderene veya kişilere atıfta bulunur.
Dilsel iletişim hitaplar ile başlar. Herhangi bir konu hakkında birisiyle birdenbire konuşmaya başlamamak toplumsal uzlaşımın bir parçasıdır. Bu bağlamda hitaplar yaşamın her anında yer bulmaktadır.
Bu makalede, Türk ve Alman dijital ortamlarda kadınların hitap ifadelerinin incelenmesi amaçlanmaktadır. İnternet günümüzde toplumun her alanındaki insanların zorunlu bir alışkanlığı haline gelmiştir. Toplumdaki bireyler etkileşimlerini büyük oranda internet aracılığı ile gerçekleştirmekte, sosyal medyayı takip ederek merak ettikleri konular hakkında fikir sahibi olabilmektedirler. Toplumda, arasında kadınların da önemli bir yere sahip olduğu büyük bir kesim günün her anında sosyal medya üzerinden iletişim kurmakta, kurdukları her tür iletişimde farklı hitap türleri sergilemektedir. Bu çalışma, kullandıkları hitaplar açısından kadınların dilsel davranışlarını içermektedir. Bilindiği gibi kadınlar ve erkekler birçok açıdan ayrıdırlar. Kadın ve erkekler arasındaki bu farklılıklar kendine dijital ortamda da yer bulmaktadır.
Makalenin birinci bölümünü oluşturan kuramsal kısımda, hitapların tanımından yola çıkılarak konunun ayrıntıları ortaya konacaktır. Çalışmanın uygulama bölümünde, Türkçe ve Almancadaki sosyal medya metinleri her iki dilde hitaplar açısından karşılaştırılarak incelenecektir. Elde edilen veriler kadınların iki dildeki hitap kullanımı bağlamında değerlendirilecektir. Bu değerlendirme sonucunda Türkçe ve Almancada kadın dilinin hitaplar açısından nasıl bir kullanım alanının olduğu görülecek, her iki dilde ne tür farklılıklar ve benzerliklerin gözlemlenebildiği sonucuna ulaşılacaktır.
Çalışmada Türkçe ve Almanca hitaplar karşılaştırılacağından inceleme genel olarak kontrastif söylem analizi ve deskriptif-analitik yöntemler doğrultusunda karma bir yöntem ile yürütülecektir.