bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distances to Galactic X-ray binaries with Gaia DR2
Authors: Arnason R M , Papei H , Barmby P , Bahramian A , D. Gorski M 
Published: February 2021

ABSTRACT
Precise and accurate measurements of distances to Galactic X-ray binaries (XRBs) reduce uncertainties in the determination of XRB physical parameters. We have cross-matched the XRB catalogues of Liu, van Paradijs & van den Heuvel to the results of Gaia Data Release 2. We identify 86 XRBs with a Gaia candidate counterpart, of which 32 are low-mass X-ray binaries (LMXBs) and 54 are high-mass X-ray binaries (HMXBs). Distances to Gaia candidate counterparts are, on average, consistent with those measured by Hipparcos and radio parallaxes. When compared to distances measured by Gaia candidate counterparts, distances measured using Type I X-ray bursts are systematically larger, suggesting that these bursts reach only 50 per cent of the Eddington limit. However, these results are strongly dependent on the prior assumptions used for estimating distance from the Gaia parallax measurements. Comparing positions of Gaia candidate counterparts for XRBs in our sample to positions of spiral arms in the Milky Way, we find that HMXBs exhibit mild preference for being closer to spiral arms; LMXBs exhibit mild preference for being closer to interarm regions. LMXBs do not exhibit any preference for leading or trailing their closest spiral arm. HMXBs exhibit a mild preference for trailing their closest spiral arm. The lack of a strong correlation between HMXBs and spiral arms may be explained by star formation occurring closer to the mid-point of the arms, or a time delay between star formation and HMXB formation manifesting as a spatial separation between HMXBs and the spiral arm where they formed.
Ionic liquid-based electrolytes for CO2 electroreduction and CO2 electroorganic transformation
Authors: Tan Xingxing , Sun Xiaofu , Han Buxing 
Published: February 2021

AbstractCO2 is an abundant and renewable C1 feedstock. Electrochemical transformation of CO2 can integrate CO2 fixation with renewable electricity storage, providing an avenue to close the anthropogenic carbon cycle. As a new type of green and chemically tailorable solvent, ionic liquids (ILs) have been proposed as highly promising alternatives for conventional electrolytes in electrochemical CO2 conversion. This review summarizes major advances in the electrochemical transformation of CO2 into value-added carbonic fuels and chemicals in IL-based media in the past several years. Both the direct CO2 electroreduction (CO2ER) and CO2-involved electroorganic transformation (CO2EOT) are discussed, focusing on the effect of electrocatalysts, IL components, reactor configurations and operating conditions on catalytic activity, selectivity and reusability. The reasons for the enhanced CO2 conversion performance by ILs are also discussed, providing guidance for the rational design of novel IL-based electrochemical processes for CO2 conversion. Finally, the critical challenges remaining in this research area and promising directions for future research are proposed.
An evaluation of REACTMH mental health training for healthcare supervisors
Authors: Akhanemhe R , Wallbank S , Greenberg N 
Published: February 2021

Abstract

Background
Healthcare workers (HCWs) are vulnerable to developing mental ill-health. Prior research has shown those in managerial or supervisory positions have pivotal roles in creating a healthy work environment, as well as recognizing and supporting HCWs with mental health symptoms to improve occupational outcomes and reduce sickness absence.

Aims
To evaluate the effectiveness of active listening skills training (REACTMH) for UK healthcare managers.

Methods
Managers of HCWs were voluntarily enrolled on a REACTMH active listening skills training package. Attendees anonymously completed questionnaires before and immediately after attending the 1-h remote training session and again 1 month later. The questionnaire asked about confidence in recognizing, conversing with and supporting distressed colleagues as well as perceived usefulness and importance of the training and how often they had used the taught active listening skills.

Results
Fifty-eight healthcare managers enrolled onto the REACTMH programme in July 2020 and 32 (55%) completed the 1-month follow-up. Just less than half reported feeling confident in being able to identify, speak to and support potentially distressed staff before the training; significantly more (&gt;80%) reported feeling confident 1 month afterwards (P &lt; 0.001). Around three-quarters of attendees reported the REACTMH programme as highly useful, highly important and said they had frequently used the learned skills.

Conclusions
A brief active listening skills training package was associated with significant improvements healthcare manager’s confidence in recognizing, speaking with and supporting HCWs with suspected mental health conditions. Further research is needed to investigate the longer term effectiveness and acceptability of REACTMH training.
Nasopharyngeal Panbio COVID-19 Antigen Performed at Point-of-Care Has a High Sensitivity in Symptomatic and Asymptomatic Patients With Higher Risk for Transmission and Older Age
Authors: Masiá Mar , Fernández-González Marta , Sánchez Manuel , Carvajal Mar , García José Alberto , Gonzalo-Jiménez Nieves , Ortiz de la Tabla Victoria , Agulló Vanesa , Candela Inmaculada , Guijarro Jorge , Gutiérrez José Antonio , de Gregorio Carlos , Gutiérrez Félix 
Published: February 2021

Abstract

Background
Performance of point-of-care tests in different clinical scenarios and on different samples remains undetermined. We comprehensively evaluated the performance of the nasopharyngeal Panbio COVID-19 Ag Rapid Test Device.

Methods
This is a prospective study that includes consecutive patients attending 3 primary care centers (PCCs) and an emergency department. The antigen test was performed at point-of-care in nasopharyngeal and nasal swabs and in saliva. Positive percent agreement (PPA) and negative percent agreement (NPA) were calculated with the reverse-transcription polymerase chain reaction (RT-PCR) assay as reference standard.

Results
Of 913 patients included, 296 (32.3%) were asymptomatic and 690 (75.6%) came from the PCC. Nasopharyngeal swabs were collected from 913 patients, nasal swabs were collected from 659 patients, and saliva was collected from 611 patients. The RT-PCR was positive in 196 (21.5%) nasopharyngeal samples (NPS). Overall, PPA (95% CI) in NPS was 60.5% (53.3–67.4), and it was lower in nasal swabs (44.7%) and saliva (23.1%). Test performance in NPS was largely dependent on the cycle threshold (Ct) in RT-PCR, with PPA of 94% for Ct ≤25 and 80% for Ct &lt;30. In symptomatic patients, the PPA was 95% for Ct ≤25, 85% for Ct &lt;30, and 89% for the symptom triad of fever, cough, and malaise. Performance was also dependent on age, with a PPA of 100% in symptomatic patients &gt;50 years with Ct &lt;25. In asymptomatic patients, the PPA was 86% for Ct &lt;25. In all cases, NPA was 100%.

Conclusions
The nasopharyngeal Panbio COVID-19 Ag test performed at point-of-care has a good sensitivity in symptomatic patients with Ct &lt;30 and older age. The test was useful to identify asymptomatic patients with lower Ct values.
Cephalopod paralarval species richness, abundance and size structure during the 2014–2017 anomalous warm period in the southern Gulf of California
Authors: Martínez-Soler Elizabeth , Gómez-Gutiérrez Jaime , de Silva-Dávila Roxana , González-Rodríguez Eduardo , Aburto-Oropeza Octavio 
Published: February 2021

AbstractCephalopod paralarval species richness, abundance and size structure were surveyed wduring an anomalous warm period (2014–2017) in the Cabo Pulmo National Park (CPNP), Gulf of California, Mexico. Paralarval taxa from six families (Cranchiidae, Enoploteuthidae, Ommastrephidae, Onychoteuthidae, Argonautidae and Octopodidae) were identified. Most taxa were of tropical biogeographic affinity and oceanic habitats. Highest paralarval richness occurred during spring associated with the northward movement of Tropical Surface Water, while the lowest was recorded during autumn with the southward flow of the Gulf of California water mass. Although 89% of the paralarvae were collected at or close to their species hatching size, none of the paralarval taxa showed a consistent seasonal spawning period. A canonical correspondence analysis showed three taxonomic assemblages: Argonauta and Helicocranchia–Onychoteuthis groups correlated with northward currents and high zooplankton biovolumes (ZB) and SD complex–Abraliopsis group with southward currents and intermediate ZB. Our Helicocranchia pfefferi paralarvae are the first recorded for the Gulf of California. At least 11 cephalopod taxa reproduce in CPNP. This area represents a suitable spawning habitat for cephalopods of socio-economic value.
Container volume may affect growth rates of ciliates and clearance rates of their microcrustacean predators in microcosm experiments
Authors: Weisse Thomas , Lukić Dunja , Lu Xiaoteng 
Published: February 2021

AbstractWe studied the effect of volume in small containers (microcosms) on five common planktonic freshwater ciliates and three zooplankton species, namely Daphnia sp., the calanoid copepod Eudiaptomus sp., and the cyclopoid copepod Cyclops sp. We measured ciliate specific growth rates and their loss rates due to microcrustacean predation in short-term experiments. We hypothesized that container volume ranging from 10 to 200 mL would not affect the activity of our prey and predator species. We found that the response to volume was species-specific; growth rates of three ciliate species were sensitive to volume. However, the volume effect was not unequivocal because different timing of the microcosm experiments (block effects) may have caused random bias due to varying morphological and/or physiological conditions of the ciliates and their predators. For predator clearance rate, the volume effect was insignificant in the filter-feeding Daphnia and Eudiaptomus but was significant for the predatory copepod Cyclops, which was hampered in the smallest experimental containers. Total crustacean clearance rates averaged over all treatments appeared unaffected by predator species, while ciliate species significantly affected the results. Our growth and clearance rates are close to previous findings with the same or similar planktonic prey and predator species.
Estimating the population health burden of musculoskeletal conditions using primary care electronic health records
Authors: Yu Dahai , Peat George , Jordan Kelvin P , Bailey James , Prieto-Alhambra Daniel , Robinson Danielle E , Strauss Victoria Y , Walker-Bone Karen , Silman Alan , Mamas Mamas , Blackburn Steven , Dent Stephen , Dunn Kate , Judge Andrew , Protheroe Joanne , Wilkie Ross 
Published: February 2021

Abstract

Objectives
Better indicators from affordable, sustainable data sources are needed to monitor population burden of musculoskeletal conditions. We propose five indicators of musculoskeletal health and assessed if routinely available primary care electronic health records (EHR) can estimate population levels in musculoskeletal consulters.

Methods
We collected validated patient-reported measures of pain experience, function and health status through a local survey of adults (≥35 years) presenting to English general practices over 12 months for low back pain, shoulder pain, osteoarthritis and other regional musculoskeletal disorders. Using EHR data we derived and validated models for estimating population levels of five self-reported indicators: prevalence of high impact chronic pain, overall musculoskeletal health (based on Musculoskeletal Health Questionnaire), quality of life (based on EuroQoL health utility measure), and prevalence of moderate-to-severe low back pain and moderate-to-severe shoulder pain. We applied models to a national EHR database (Clinical Practice Research Datalink) to obtain national estimates of each indicator for three successive years.

Results
The optimal models included recorded demographics, deprivation, consultation frequency, analgesic and antidepressant prescriptions, and multimorbidity. Applying models to national EHR, we estimated that 31.9% of adults (≥35 years) presenting with non-inflammatory musculoskeletal disorders in England in 2016/17 experienced high impact chronic pain. Estimated population health levels were worse in women, older aged and those in the most deprived neighbourhoods, and changed little over 3 years.

Conclusion
National and subnational estimates for a range of subjective indicators of non-inflammatory musculoskeletal health conditions can be obtained using information from routine electronic health records.
What is the meaning of ANCA positivity in IgG4-related disease?
Authors: Martín-Nares Eduardo , Hernandez-Molina Gabriela 
Published: February 2021

Abstract

Objectives
To evaluate the prevalence and meaning of antineutrophil cytoplasmic antibodies (ANCA) positivity in a cohort of IgG4-related disease (IgG4-RD).

Methods
We identified patients with ANCA determination from a retrospective cohort of 69 patients with IgG4-RD. ANCA were measured by indirect immunofluorescence microscopy (IIF) and/or proteinase 3 (PR3)-ANCA and MPO-ANCA by ELISA. IIF patterns were classified as perinuclear (P-ANCA), cytoplasmic (C-ANCA) and atypical (X-ANCA). We compared the ANCA-positive vs the ANCA-negative IgG4-RD group.

Results
Out of 69 patients, 31 IgG4-RD patients had an ANCA determination. Four patients with concomitant systemic autoimmune diseases were excluded. We found positive ANCA by IIF in 14 (56%) of 25 patients tested. The most common IIF pattern was C-ANCA in eight (57.1%), followed by dual C-ANCA/X-ANCA in four (28.6%) and P-ANCA and dual C-ANCA/P-ANCA in one each (7.1%). Of the 20 patients with ANCA determination by both IIF and ELISA, four have positive ANCA by ELISA (three for MPO-ANCA and one for PR3-ANCA). Of the two patients with only ELISA determination, one was positive for MPO-ANCA. The prevalence of ANCA positivity by ELISA was 22.7% (5 out of 22 patients). ANCA was more frequent in the Mikulizc/systemic phenotype (42.9%) compared with other phenotypes (P = 0.04). ANCA-positive IgG4-RD patients had more frequently lymph node and kidney involvement, high IgG1 levels and erythrocyte sedimentation rate, and positive antinuclear antibodies.

Conclusion
ANCA are found in a significant number of patients with IgG4-RD and differed from the ANCA-negative group in terms of clinical and serological features.
MINIMIZING THE EXPOSURE TO THE EYE LENS OF RADIOLOGIC TECHNOLOGISTS ASSISTING PATIENTS DURING CHEST X RAYS: A PHANTOM STUDY
Authors: Mitsuyoshi Yasuda , Tomoya Funada , Hisaya Sato , Kyoichi Kato 
Published: February 2021

Abstract
As chest x rays involve risks of patients falling, radiologic technologists (technologists) commonly assist patients, and as the assistance takes place near the patients, the eye lenses of the technologists are exposed to radiation. The recommendations of the International Commission on Radiological Protection suggest that the risk of developing cataracts due to lens exposure is high, and this makes it necessary to reduce and minimize the exposure. The present study investigated the positions of technologists assisting patients that will minimize exposure of the eye lens to radiation. The results showed that it is possible to reduce the exposure by assisting from the following positions: 50% at the sides rather than diagonally behind, 10% at the right side of the patient rather than the left and 40% at 250 mm away from the patient. The maximum reduction with radiation protection glasses was 54% with 0.07 mmPb and 72% with 0.88 mmPb.
Physical Activity Interventions for Individuals With a Mild Traumatic Brain Injury:
Authors: Alarie Christophe , Gagnon Isabelle , Quilico Enrico , Teel Elizabeth , Swaine Bonnie 
Published: February 2021

Objective:
To document the characteristics, measured outcomes, and effectiveness of physical activity (PA) interventions designed to improve health-related outcomes in individuals with a mild traumatic brain injury (mTBI) to assist in rehabilitation quality improvement efforts of a TBI rehabilitation program.

Methods:
A scoping review following a 6-step iterative framework search across 5 databases (MEDLINE, CINAHL, PsycINFO, SPORTDiscuss, and EMBASE) and the gray literature (Google) was performed. Selected PA interventions were designed for individuals of all ages and any mechanism of injury (eg, sports-related and falls). Data were charted, collated, and summarized according to the Consensus on Exercise Reporting Template checklist and domains of the International Classification of Functioning, Disability and Health. Involvement of clinical experts ensured tailoring of the knowledge synthesis to meet clinical needs.

Results:
Thirty-five articles and 14 gray literature records were retained. Five types of PA interventions were identified with the majority being multimodal. Reporting of PA intervention characteristics was highly variable across studies; many details necessary for intervention replication are missing. Study outcomes focused primarily on improving body functions and symptoms of mTBI, and less frequently on activities, participation, and health-related quality of life. The methodological quality of studies varies.

Conclusions:
Identified PA intervention types offer various management options for healthcare providers. PA interventions may improve a wide range of health-related outcomes supporting the inclusion of PA in the management of individuals of all ages with mTBI. Higher-quality research and better reporting about intervention characteristics is however needed.
Efficacy of Ivermectin in COVID-19 Patients with Mild to Moderate Disease
Authors: Shah Bukhari Karamat Hussain , Asghar Asma , Perveen Najma , Hayat Arshad , Mangat Sermad Ahmad , Butt Kamil Rehman , Abdullah Mohammad , Fatima Tehreem , Mustafa Ahmad , Iqbal Talal 
Published: February 2021

AbstractObjectiveTo evaluate the efficacy of ivermectin (IVM) as an addition to the standard of care (SOC) treatment in COVID-19 patients with mild and moderate diseaseMaterials and MethodsA randomized clinical trial (Trial registration # NCT04392713) was carried out at Combined Military Hospital Lahore from March 15, 2020, to June 15, 2020. Eighty-six patients with reverse transcriptase-polymerase chain reaction (RT-PCR) proven SARS-CoV-2 infection completed the trial protocol. Patients were stratified via the lottery method into two groups. Group A was administered standard of care (SOC) treatment as per existing hospital guidelines whereas group B was given ivermectin (single dose of 12 milligrams) along with SOC treatment. PCR was repeated at 72 hours, 7th day, and at 14th day of admission for both the groups and the point at which the PCR became negative was noted. Complete blood counts, liver function tests and renal function tests were done at recruitment, 7th day, and 14th day. The primary outcome was the viral clearance, measured as days to achieve PCR negativity. The secondary outcome was the development of any adverse side effects pertinent to ivermectin or derangement in baseline laboratory parameters.ResultsIn group A, 36 (80%) participants were males, and 9 (20%) were females, whereas in group B, 37 (90.2%) were males and 4 (9.8%) were females. Mean age was 39.0± 12.6 and 42.2 ± 12.0 years for groups A and B, respectively (p= 0.394). There was early viral clearance in group B as compared to group A (p=0.001). No adverse reaction or derangements in laboratory parameters was noted in the intervention arm during the trial period.ConclusionIn the intervention arm, early viral clearance was observed and no side effects were documented. Therefore ivermectin is a potential addition to the standard care of treatment in COVID-19 patients.
Thromboembolic risk in hospitalised and non-hospitalised Covid-19 patients: A self-controlled case series analysis of a nation-wide cohort
Authors: Ho Frederick K , Man Kenneth KS , Toshner Mark , Church Colin , Celis-Morales Carlos , Wong Ian CK , Berry Colin , Sattar Naveed , Pell Jill P 
Published: February 2021

AbstractObjectiveAn unexpectedly large number of people infected with Covid-19 had experienced a thrombotic event. This study aims to assess the associations between Covid-19 infection and thromboembolism including myocardial infarction (MI), ischaemic stroke, deep-vein thrombosis (DVT), and pulmonary embolism (PE).Patients and MethodsA self-controlled case-series study was conducted covering the whole of Scotland’s general population. The study population comprised individuals with confirmed (positive test) Covid-19 and at least one thromboembolic event between March 2018 and October 2020. Their incidence rates during the risk interval (5 days before to 56 days after the positive test) and the control interval (the remaining periods) were compared intra-personally.ResultsAcross Scotland, 1,449 individuals tested positive for Covid-19 and experienced a thromboembolic event. The risk of thromboembolism was significantly elevated over the whole risk period but highest in the 7 days following the positive test (IRR 12.01, 95% CI 9.91-14.56) in all included individuals. The association was also present in individuals not originally hospitalised for Covid-19 (IRR 4.07, 95% CI 2.83-5.85). Risk of MI, stroke, PE and DVT were all significantly higher in the week following a positive test. The risk of PE and DVT was particularly high and remained significantly elevated even 56 days following the test.ConclusionConfirmed Covid-19 infection was associated with early elevations in risk with MI, ischaemic stroke, and substantially stronger and prolonged elevations with DVT and PE both in hospital and community settings. Clinicians should consider thromboembolism, especially PE, among people with Covid-19 in the community.