bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extracellular fluid volume: A suitable indexation variable to assess impact of bariatric surgery on glomerular filtration rate in patients with chronic kidney disease
Authors: Grangeon-Chapon Caroline , Laurain Audrey , Esnault Vincent L. M. , Cruzel Coralie , Iannelli Antonio , Favre Guillaume A. 
Published: August 2021

Background
Bariatric surgery (BS) might be a nephroprotective treatment in obese patients with chronic kidney disease (CKD), and the non-linear relation between body surface area (BSA) and extracellular fluid volume (ECFV) in obese people raises the question of the most relevant way to scale glomerular filtration rate (GFR) for assessing renal function changes after BS.

Methods
We screened 1774 BS candidates and analysed 10 consecutive participants with CKD stage 3. True GFR (mGFR), measured by the renal clearance of 51Cr-ethylenediaminetetraacetic acid (EDTA), was scaled either to BSA (mGFRBSA) or to ECFV measured by 51Cr-EDTA distribution volume (mGFRECFV) before and one year after BS.

Results
The 10 candidates for BS had a mean body mass index of 43.3 ± 3.6 kg/m2 and a mean GFR of 48 ± 8 mL/min/1.73 m2. Six participants had a sleeve gastrectomy and four had a Roux-en-Y gastric bypass. One year after BS, ECFV decreased (23.2 ± 6.2 to 17.9 ± 4.3 L, p = 0.001), absolute mGFR was not significantly modified (74 ± 23 versus 68 ±19 mL/min), mGFRBSA did not change significantly (53 ± 18 versus 56 ± 17 mL/min/1.73 m2) whereas mGFRECFV significantly increased (42 ± 13 versus 50 ± 14 mL/min/12.9 L, p = 0.037). The relation between mGFRECFV and mGFRBSA was different from the identity line before (p = 0.014) but not after BS (p = 0.09).

Conclusion
There is a difference between mGFRBSA and mGFRECFV following BS and the latter might better reflect the adequacy between renal function and corpulence.
Influence of genetic and comorbid emotional-affective factors on pre-mild cognitive decline in middle-aged patients
Authors: Koberskaya N. N. , Ostroumova T. M. , Perepelov V. A. , Smirnov D. S. 
Published: August 2021

Recently, maximum attention has been drawn to the earliest forms of cognitive deficit - pre-mild cognitive decline (PMCD), which includes subjective (SjCD) and subtle cognitive decline (SCD), being the most promising in cognitive decline prevention.Objective: to assess the influence of genetic and comorbid emotional-affective factors on PMCD in middle-aged patients.Patients and methods. The study included 50 middle-aged people (60.76±9.5 years) with cognitive complaints. All patients underwent a cardiovascular assessment, including: biochemistry blood test (lipid profile, urea, glucose, vitamin В12, folic acid, homocysteine, thyroid hormones), duplex scan of the extracranial arteries, blood assay for АРОЕ4 determination, neuropsychological assessment with quantitative neuropsychological methods, emotional-affective background evaluation. In addition, magnetic resonance imaging (MRI) with morphometry of the hippocampus was performed in 20 patients.Results and discussion. Arterial hypertension, diabetes mellitus, and changes in laboratory parameters are significantly were more frequent in patients with SCD than patients with SjCD. The neuropsychological assessment showed maximum differences between SjCD and SCD groups in tests that evaluated reaction time (verbal fluency test, trail making test, part A, digit symbol substitution test, and Munsterberg test). Analysis of neuroimaging parameters revealed a smaller volume of the right hippocampus in APOE4 carriers. patients without depression performed significantly better on memory tasks, when depression was included in the analysis. In addition, patients with depression showed a significantly more pronounced degree of cortical atrophy on MRI.Conclusion. Patients with SCD have lower scores in neuropsychological tests than patients with SjCD. In addition, we observed a high significance of cardiovascular and emotional-affective risk factors in the PMCD development, emphasizing the importance of their evaluation and treatment in the management of patients with PMCD.
Medication adherence in migraine patients (data of an online survey)
Authors: Kovalchuk N. A. , Kiryanova E. A. , Tabeeva G. R. 
Published: August 2021

Patient needs, drug intake patterns, and adherence to therapy are significant challenges in the management of migraine patients.Objective: to identify drug treatment needs, drug use patterns and adherence factors in migraine patients.Patients and methods. An online survey was conducted among Internet users through social networks (Instagram, Facebook, Vkontakte) from 01/22/2020 to 02/22/2020. The selection of respondents was based on an anamnesis of headaches and passing the ID Migraine screener. One thousand five hundred ninety-eight individuals (93.8% women and 6.2% men) aged 18—39years participated in the survey.Results and discussion. Among 1598 participants, 1490 experienced any headache, 937 respondents noted migraine symptoms, and 542 (58.4%) had a migraine diagnosis. 899 (96%) of responders used medications to relieve headaches, and in 59% of them drugs were self-prescribed. 125 (13%) patients received prophylactic therapy for migraine, of which only 47 (37.6%) complied with the prescribed treatment. We found a significant (p=0.019) association between the degree of adherence to therapy and the number of days with migraine.Conclusion. The study revealed a low referral rate in patients with headaches. In addition, more than half self-prescribed the drug for headache relief, and only a third of patients complied with the prescribed prophylactic treatment.
Image Processing using Open Source Tools and their Implementation in the Analysis of Complex Microstructures
Authors: Nayak U. P. , Müller M. , Britz D. , Guitar M.A. , Mücklich F. 
Published: August 2021

AbstractConsidering the dependance of materials’ properties on the microstructure, it is imperative to carry out a thorough microstructural characterization and analysis to bolster its development. This article is aimed to inform the users about the implementation of FIJI, an open source image processing software for image segmentation and quantitative microstructural analysis.The rapid advancement of computer technology in the past years has made it possible to swiftly segment and analyze hundreds of micrographs reducing hours’ worth of analysis time to a mere matter of minutes. This has led to the availability of several commercial image processing software programs primarily aimed at relatively inexperienced users. Despite the advantages like ‘one-click solutions’ offered by commercial software, the high licensing cost limits its widespread use in the metallographic community.Open-source platforms on the other hand, are free and easily available although rudimentary knowledge of the user-interface is a pre-requisite. In particular, the software FIJI has distinguished itself as a versatile tool, since it provides suitable extensions from image processing to segmentation to quantitative stereology and is continuously developed by a large user community. This article aims to introduce the FIJI program by familiarizing the user with its graphical user-interface and providing a sequential methodology to carry out image segmentation and quantitative microstructural analysis.
Künstliche Intelligenz im Kompetenzmanagement
Authors: Kohl Linus , Fuchs Benedikt , Berndt Rene , Valtiner Daniel , Ansari Fazel , Schlund Sebastian 
Published: August 2021

Abstract
Die gezielte und zukunftsorientierte Aus- und Weiterbildung von Mitarbeiter:innen in technischen Unternehmen erfordert im Kontext des rapiden technologischen und demographischen Wandels innovative Lösungsansätze. Die Identifizierung und Strukturierung von kompetenzrelevanten Informationen aus unstrukturierten Unternehmensdaten mithilfe von Methoden der Künstlichen Intelligenz (KI), vor allem Text-Mining (TM), bieten hier neue Möglichkeiten, dieser Herausforderung zu begegnen. In Zusammenarbeit mit der Infineon Technologies Austria AG wurden im Bereich der Instandhaltung von Implanter-Anlagen eine skalierbare Systematik und ein Prozess, einschließlich eines mathematischen Algorithmus und eines dazugehörigen Modells, entwickelt, um Personalkompetenzen aus un- und teilstrukturierten Instandhaltungsdaten zu extrahieren.
The Impact of SST and PV Interneurons on Nonlinear Synaptic Integration in the Neocortex
Authors: Dorsett Christopher , Philpot Benjamin D. , Smith Spencer LaVere , Smith Ikuko T. 
Published: August 2021

AbstractExcitatory synaptic inputs arriving at the dendrites of a neuron can engage active mechanisms that nonlinearly amplify the depolarizing currents. This supralinear synaptic integration is subject to modulation by inhibition. However, the specific rules by which different subtypes of interneurons affect the modulation have remained largely elusive. To examine how inhibition influences active synaptic integration, we optogenetically manipulated the activity of the following two subtypes of interneurons: dendrite-targeting somatostatin-expressing (SST) interneurons; and perisomatic-targeting parvalbumin-expressing (PV) interneurons. In acute slices of mouse primary visual cortex, electrical stimulation evoked nonlinear synaptic integration that depended on NMDA receptors. Optogenetic activation of SST interneurons in conjunction with electrical stimulation resulted in predominantly divisive inhibitory gain control, reducing the magnitude of the supralinear response without affecting its threshold. PV interneuron activation, on the other hand, had a minimal effect on the supralinear response. Together, these results delineate the roles for SST and PV neurons in active synaptic integration. Differential effects of inhibition by SST and PV interneurons likely increase the computational capacity of the pyramidal neurons in modulating the nonlinear integration of synaptic output.
Dört Direkt Pulpa Kapaklama Materyalinin Klinik Takibinin Değerlendirilmesi: Bir Klinik Çalışma
Authors: VELİOĞLU Mehmet Semih , ÜNLÜ Nimet 
Published: August 2021

Amaç: Bu çalışmanın amacı, farklı pulpa kapaklama materyallerin klinik başarılarını retrospektif olarak değerlendirmek için direkt pulpa kapaklama tedavileri uygulanmış hastaları 1 yıl boyunca takip etmektir.
Gereç ve Yöntemler: Bu retrospektif takip çalışmasına, Restoratif Diş Tedavisi kliniğine çürük semptomları nedeniyle başvurmuş, 18-45 yaş aralığında, sistemik sağlık problemi olmayan, farklı pulpa kapaklama materyalleri kullanılarak direkt pulpa kapaklama tedavisi uygulanmış, daimi restorasyonları kompozit dolgu materyali ile yapılmış hastalar dahil edildi. Hastalar tedavide kullanılan pulpa kapaklama materyallerine göre 4 farklı gruba ayrıldı. Grup 1: Ca(OH)2, Grup 2: MTA, Grup 3: TheraCal LC ve Grup 4: Biodentine idi. Hastaların klinik takipleri 1. hafta, 1., 3., 6. ve 12. aylarda gerçekleştirildi. Klinik takipler için gelen hastaların ağrı, perküsyon, postoperatif hassasiyet şikayetleri değerlendirildi, soğuk testi ve elektrikli vitalite testi ile tedavi edilen dişlerin vitaliteleri ölçüldü. İstatistiksel analiz için Ki-Kare testi ve Fisher Exact testi kullanıldı.
Bulgular: Elde edilen verilere göre sağ kalım açısından en yüksek başarı oranı Biodentine grubunda %90.9 iken, en düşük başarı oranı Ca(OH)2 grubunda %80 olarak gözlendi. MTA grubunda başarı oranı %84, TheraCal LC grubunda ise %81.8’lik bir başarı oranı tespit edildi. Gruplar karşılaştırıldığında sağ kalım oranları açısından başarı oranları arasında istatistiksel olarak anlamlı bir fark olmadığı gözlendi.
Sonuç: Direkt pulpa kapaklamasında kullanılmak için üretilen materyallerin kısa dönem klinik takiplerinde dişlerin canlılığını korumada etkili oldukları ve klinik başarı oranlarının benzer olduğu, ancak materyallerin uzun dönem klinik başarılarının daha iyi anlaşılabilmesi için daha fazla hasta katılımlı ve uzun dönem takipli çalışmalara ihtiyaç vardır.
Opioid Prescribing to US Children and Young Adults in 2019
Authors: Chua Kao-Ping , Brummett Chad M. , Conti Rena M. , Bohnert Amy S. 
Published: August 2021

BACKGROUND
Recent national data are lacking on the prevalence, safety, and prescribers of opioid prescriptions dispensed to children and young adults aged 0 to 21 years.

METHODS
We identified opioid prescriptions dispensed to children and young adults in 2019 in the IQVIA Longitudinal Prescription Database, which captures 92% of US pharmacies. We calculated the proportion of all US children and young adults with ≥1 dispensed opioid prescription in 2019. We calculated performance on 6 metrics of high-risk prescribing and the proportion of prescriptions written by each specialty. Of all prescriptions and those classified as high risk by ≥1 metric, we calculated the proportion written by high-volume prescribers with prescription counts at the ≥95th percentile.

RESULTS
Analyses included 4 027 701 prescriptions. In 2019, 3.5% of US children and young adults had ≥1 dispensed opioid prescription. Of prescriptions for opioid-naive patients, 41.8% and 3.8% exceeded a 3-day and 7-day supply, respectively. Of prescriptions for young children, 8.4% and 7.7% were for codeine and tramadol. Of prescriptions for adolescents and young adults, 11.5% had daily dosages of ≥50 morphine milligram equivalents; 4.6% had benzodiazepine overlap. Overall, 45.6% of prescriptions were high risk by ≥1 metric. Dentists and surgeons wrote 61.4% of prescriptions. High-volume prescribers wrote 53.3% of prescriptions and 53.1% of high-risk prescriptions.

CONCLUSIONS
Almost half of pediatric opioid prescriptions are high risk. To reduce high-risk prescribing, initiatives targeting high-volume prescribers may be warranted. However, broad-based initiatives are also needed to address the large share of high-risk prescribing attributable to other prescribers.
Удосконалення техніко-тактичної підготовки кваліфікованих стрільців з пневматичної гвинтівки на етапі спеціалізованої базової підготовки
Authors: Лопатьєв Анатолій , Демічковський Андрій 
Published: August 2021

Мета дослідження – встановити особливості техніко-тактичної підготовки кваліфікованих стрільців з пневматичної гвинтівки на етапі спеціалізованої базової підготовки. Матеріали та методи. Для вирішення поставлених завдань було використано наступні методи дослідження: аналіз та узагальнення науково-методичної літератури, педагогічні спостереження. Аналіз науково-методичної літератури дав змогу встановити, що кількість індивідуальних програм з підготовки стрільців з пневматичної гвинтівки не задовольняє сучасні потреби стрілецького спорту. Педагогічні спостереження використано для вивчення особливостей техніко-тактичного виконання змагальних вправ кваліфікованих спортсменів, а також їх рухових здібностей. Результати. Аналіз змагальної діяльності дозволив визначити, що фази виконання пострілу «прицілювання», «виконання пострілу – активний постріл», «налаштування на постріл» є інформативними показниками техніко-тактичних дій кваліфікованих спортсменів у стрільбі з пневматичної гвинтівки. Було проаналізовано ряд навчально-методичних документів: навчальна програма з підготовки стрільців з кульової стрільби для дитячо-юнацьких спортивних шкіл, спеціалізованих дитячо-юнацьких шкіл олімпійського резерву, шкіл вищої спортивної майстерності та навчальних закладів спортивного профілю; спеціалізована література з підготовки стрільців. У процесі аналізу визначено, що співвідношення наведених сторін підготовки не дає можливості проведення ефективного процесу підготовки спортсменів для досягнення високих спортивних результатів в межах діючих правил змагальної діяльності. Висновки. Детальний аналіз спеціалізованої навчально-методичної літератури для стрільців з пневматичної гвинтівки дозволив встановити, що в групах спеціалізованої базової підготовки спортсменів усі види підготовки виглядають наступним чином: теоретична підготовка зменшується з 3,44 % до 2,6 %, загальна фізична зменшується з 15,0 % до 13,2 %, спеціальна фізична підготовка зменшується з 17,21 % до 15 %, технічна підготовка зростає з 53,5 % до 54,7 %, участь у змаганнях збільшується з 9,05 % до11,7 %, інструкторська та суддівська практика зростає з 1,8 % до 2,8 %.
“There are Always Ways to Cheat” Academic Dishonesty Strategies During Online Learning
Authors: Herdian Herdian , Mildaeni Itsna Nurrahma , Wahidah Fatin Rohmah 
Published: August 2021

Since the implementation of online learning in various countries in the world, all educational institutions have made new learning adjustments. Universities are educational institutions that have also changed the online learning system. but online learning has an impact on academic ethical behavior. Purpose. the aims of this study is to determine the behavior of academic dishonesty when online learning is applied, besides that it also examines the strategies of nursing students majoring in academic dishonesty. Materials and methods. 150 college students participated in filling out an online academic dishonesty questionnaire and we randomly selected 5 nursing students to participate in a focus group discussion to discuss their dishonest behavior during online learning. Results. Our research shows that academic dishonesty behavior in the form of collaboration is common in online learning. In the process, student learning has strategies for committing academic fraud in various ways, including by downloading a friend’s answer file in the online system by logging in using a standard username and password that is not changed by students. In addition, the student chose to behave dishonestly by imitating his friend’s work by simply changing the name rather than trying to answer the question. and take advantage of the whatsapp group application to collaborate in cheating. Conclusions. Collaboration in academic dishonesty predominates: one way is by collaborating in online groups to cooperate with each other illegally. We describe several other forms in detail and discuss them.
Człowieczeństwo jako problem i wyzwanie edukacyjne
Authors: Ostrowska Urszula 
Published: August 2021

Kwestia sposobów zaświadczania człowieczeństwa przez ludzi współczesnych przybiera ran­gę priorytetowego zadania współczesności i wyzwania wykraczającego w przyszłość. Zawarta w tytule artykułu triada kategorii kluczowych: człowieczeństwo – problem – wyzwanie edu­kacyjne stanowi tropy wytyczające tok rozważań podjętych w niniejszym tekście. Rozpoczynam je od ujęć terminologicznych, a następnie prezentuję podjęte kwestie z jednej strony z per­spektywy postrzegania człowieczeństwa jako priorytetowego problemu i wyzwania dla ludzkości, który wymaga intensywnych zabiegów epistemologiczno-eksploracyjnych, z drugiej strony jako konstytutywnej podstawy dla teorii i praktyki edukacyjnej ukierunkowanej na wnikliwe po­znawanie człowieczeństwa, a także odpowiedzialne zaświadczanie przez podmioty edukacyjne tego fenomenu w universum antroposferycznym, w którym podejmowane próby doskonalenia elementów świata wartości nie mają kresu.
The Role of Tuan Guru on Improving Iron Intake and Minimalizing Food Restriction Behavior among Pregnant Women with Anemia
Authors: Khairi Sabi'ah , Siswanto Lalu Muhammad Harmain , Bahtiar Heri , Ristrini Ristrini 
Published: August 2021

Introduction: Anemia in pregnancy is an indirect cause maternal mortality. One of causes anemia during pregnancy is deficit of nutrient especially intake of iron. The aim of this study was to know that the role of religious leaders that called “Tuan Guru” as agent of change to improving iron intake among anemia pregnant women.Methods: This study was quasi-experimental with pre and post-test group design. 86 participants pregnant women with anemia have been recruited in this study with purposive sampling technic. They were divided in intervention group (47 participants) and control group (39 participants). This study involved Tuan Guru as main intervention to give health promotion about nutrition during pregnancy. This study used food recall as an instrument tool that it used to measure nutrient intake especially intake of iron both pre and post intervention and also used questonare to measure food restriction behaviour among anemia pregnant women. Statistical test used paired t-testResults: This study show that there were effect of religious leaders to improving the iron intake among pregnant women with anemia with p=0.01. This study also found that the habits of food restriction among pregnant women are decline between before and after intervention with p=0.00.Conclusion: Tuan Guru has a strong influence in helping to increase nutritional intake and is able to minimize the food restriction behaviour among anemia pregnant women. The result of this study can be a basis for government to make a policy related to involvement of religious leaders in health promotion.
PEMANFAATAN SUMBERDAYA HUTAN OLEH SUKU DAYAK MERATUS KALIMANTAN SELATAN
Authors: Rezekiah Arfa Agustina , Fithria Abdi , Rahmadi Adi 
Published: August 2021

Dayak Meratus in Loklahung Village, Loksado District, South Hulu Sungai Regency, South Kalimantan is one of the tribes living around the forest. They use forest resources to meet their daily needs. This research aims to analized the utilization of types and the forms of forest resources by indigenous peoples. Data collecting that used in this research are in-depth interviews and field observations. The analysis of data used tabulation matrix and qualitative description. The results showed that the utilization of forest resources is inherited from ancestors. The utilization of forest resources is mostly carried out in the forest in the form of activities: (1) Finding fuel and firewood; (2) Hunting; (3) Looking for handicraft materials; (4) Looking for nontimber forest products and (5). Looking for medicinal ingredients. The perception of dayak meratus people to the impact of forest resource utilization both flora and fauna belongs to the moderate category.
The perspectives and experiences of physiotherapists and general practitioners in the use of the STarT Back Tool Tool: A review and meta-synthesis.
Authors: Hill Julia , Try Freya , Agnew Georgia , Saywell Nicola 
Published: August 2021

Abstract
Background: Chronic low back pain is associated with disability and work absence. Stratified primary care management of acute low back pain using a prognostic screening tool (STarT Back Tool, SBT) triages people with LBP into targeted treatment groups, matched to their level of risk of chronicity. The SBT was designed for use in the health service in the United Kingdom where it has been shown to improve clinical outcomes, patient satisfaction, and reduce treatment costs and time off work. Successful implementation of the SBT outside the UK is dependent on the health practitioners who will use it and the healthcare system in which they work. Gaining health practitioners’ perspectives on the SBT is an important step in implementation. Methods: A computerised search of qualitative literature was conducted across seven databases in March 2021 using keywords to identify studies investigating the perspectives of physiotherapists and general practitionners on the use of the SBT in primary health care. Study quality was assessed using the CASP tool. Data were coded and analysed using reflexive thematic analysis. Results: Eight articles met inclusion criteria and included the views of general practitionners and physiotherapists from primary health care settings from four countries. Three themes were created from the data, the first ‘making it work’, identifies factors that may influence implementation and continued use of the SBT in clinical practice. The second ‘will I do it?’, captured potential consequences of adopting the SBT and the third, ‘it’s all about the patient’ emphasised how the SBT may affect patients and their potential reactions. Conclusions: Physiotherapists and general practitionners found using the SBT frequently enhanced their practice. General practitioners expressed concerns about time constraints and potential for the SBT to undermine their clinical experience. Findings from this study will inform modifications to contextualise the tool to each healthcare environment.