bluuebunny/crossref_metadata_2025_split huggingface dataset:
How Positively Valenced Health Messages can Foster Information Selection: Evidence from Two Experiments
Authors: Ort Alexander , Siegenthaler Perina , Fahr Andreas 
Published: March 2021

Objective: Positively valenced appeals have received comparably less attention than negative appeals. However, messages utilizing negative emotions have been repeatedly criticized, and research has demonstrated the beneficial effects of applying positive emotionally-charged messages. Therefore, this study investigates the impact and effectiveness of positive to negative messages.Design: In two studies (N1 = 108, N2 = 355), participants were exposed to one video about healthy eating and exercising, which was manipulated concerning valence (positive vs. negative).Main Outcome Measures: We assessed efficacy perceptions and attitudes toward healthy eating and exercising as well as participants’ selection of topic-related information on a mock-up website immediately after message exposure.Results: A positive emotional experience led to stronger efficacy perceptions, which promoted attitudes toward the displayed behavior but not information selection (Study 1). A more diverse sample in a follow-up replication (Study 2) substantiated these findings. Additionally, it demonstrated that being affected by a health issue has a decisive influence on the selection of information. In particular, a higher BMI negatively influenced information selection when efficacy perceptions were high.Conclusion: The study demonstrates the double-edged nature of strengthening efficacy expectations, as they can promote healthy attitudes and provide affected individuals with a false sense of security.
Association Between Lipoprotein (A) and Diabetic Nephropathy in Patients With Type 2 Diabetes Mellitus: A Meta-Analysis
Authors: Ren Xiaoyan , Zhang Zhihui , Yan Zhaoli 
Published: March 2021

BackgroundLipoprotein (a) [Lp (a)] has been well recognized as a risk factor of cardiovascular disease. However, the association between serum Lp (a) and diabetic nephropathy in patients with type 2 diabetes mellitus (T2DM) remains unknown. We performed a meta-analysis to comprehensively evaluate the above association.MethodsObservational studies aiming to evaluate the independent association between serum Lp (a) and diabetic nephropathy in T2DM patients were identified by systematic search of PubMed and Embase databases. A random-effect model which incorporated the potential intra-study heterogeneity was used for the meta-analysis.ResultsEleven observational studies with 9304 T2DM patients were included. Results showed that compared to those with the lowest Lp (a), patients with the highest Lp (a) level had higher odds of diabetic nephropathy (adjusted odds ratio [OR]: 1.63, 95% confidence interval [CI]: 1.25–2.14, I2 = 54%, P &lt; 0.001). Meta-analysis of studies in which Lp (a) was presented as continuous variables showed consistent result (adjusted OR: 1.13 for 1 mg/dl increment of Lp (a), 95% CI: 1.03–1.24, I2 = 36%, P = 0.008). Subgroup analyses showed that study characteristics such as definitions of diabetic nephropathy and study design did not significantly affect the association (P for subgroup difference all &gt; 0.05).ConclusionsHigher serum Lp (a) in patients with T2DM is independently associated with higher odds of diabetic nephropathy. Large scale prospective cohort studies are needed to validate this finding. Moreover, the potential influence of Lp (a) lowering on renal function in T2DM patients may be further investigated.
Increased Screen Time Is Associated With Alcohol Desire and Sweetened Foods Consumption During the COVID-19 Pandemic
Authors: Tebar William R. , Christofaro Diego G. D. , Diniz Tiego A. , Lofrano-Prado Mara Cristina , Botero Joao Paulo , Correia Marilia de Almeida , Cucato Gabriel G. , Ritti-Dias Raphael Mendes , Prado Wagner Luiz do 
Published: March 2021

Background: Elevated screen time has been associated with addictive behaviors, such as alcohol and sugar intake and smoking. Considering the substantial increase in screen time caused by social isolation policies, this study aimed to analyze the association of increased screen time in different devices during the COVID-19 pandemic with consumption and increased desire of alcohol, smoking, and sweetened foods in adults.Methods: A sample of 1,897 adults with a mean age of 37.9 (13.3) years was assessed by an online survey, being composed by 58% of women. Participants were asked whether screen time in television, cell phone, and computer increased during the pandemic, as well as how much time is spent in each device. Closed questions assessed the frequency of alcohol and sweetened food consumption, smoking, and an increased desire to drink and smoke during the pandemic. Educational level, age, sex, feeling of stress, anxiety, depression, and use of a screen device for physical activity were covariates. Binary logistic regression models considered adjustment for covariates and for mutual habits.Results: Increased television time was associated with increased desire to drink (OR = 1.46, 95% CI: 1.12; 1.89) and increased sweetened food consumption (OR = 1.53, 95% CI: 1.18; 1.99), while an increase in computer use was negatively associated with consumption of alcohol (OR = 0.68, 95% CI: 0.53; 0.86) and sweetened foods (OR = 0.78, 95% CI: 0.62; 0.98). Increased cell phone time was associated with increased sweetened food consumption during the pandemic (OR = 1.78, 95% CI: 1.18; 2.67). Participants with increased time in the three devices were less likely to consume sweetened foods for ≥5 days per week (OR = 0.63, 95% CI: 0.39; 0.99) but were twice as likely to have sweetened food consumption increased during pandemic (OR = 2.04, 95% CI: 1.07; 3.88).Conclusion: Increased screen time was differently associated with consumption and desire for alcohol and sweets according to screen devices. Increased time in television and cell phones need to be considered for further investigations of behavioral impairments caused by the pandemic.
Deep Learning for Automatic Segmentation of Oral and Oropharyngeal Cancer Using Narrow Band Imaging: Preliminary Experience in a Clinical Perspective
Authors: Paderno Alberto , Piazza Cesare , Del Bon Francesca , Lancini Davide , Tanagli Stefano , Deganello Alberto , Peretti Giorgio , De Momi Elena , Patrini Ilaria , Ruperti Michela , Mattos Leonardo S. , Moccia Sara 
Published: March 2021

IntroductionFully convoluted neural networks (FCNN) applied to video-analysis are of particular interest in the field of head and neck oncology, given that endoscopic examination is a crucial step in diagnosis, staging, and follow-up of patients affected by upper aero-digestive tract cancers. The aim of this study was to test FCNN-based methods for semantic segmentation of squamous cell carcinoma (SCC) of the oral cavity (OC) and oropharynx (OP).Materials and MethodsTwo datasets were retrieved from the institutional registry of a tertiary academic hospital analyzing 34 and 45 NBI endoscopic videos of OC and OP lesions, respectively. The dataset referring to the OC was composed of 110 frames, while 116 frames composed the OP dataset. Three FCNNs (U-Net, U-Net 3, and ResNet) were investigated to segment the neoplastic images. FCNNs performance was evaluated for each tested network and compared to the gold standard, represented by the manual annotation performed by expert clinicians.ResultsFor FCNN-based segmentation of the OC dataset, the best results in terms of Dice Similarity Coefficient (Dsc) were achieved by ResNet with 5(×2) blocks and 16 filters, with a median value of 0.6559. In FCNN-based segmentation for the OP dataset, the best results in terms of Dsc were achieved by ResNet with 4(×2) blocks and 16 filters, with a median value of 0.7603. All tested FCNNs presented very high values of variance, leading to very low values of minima for all metrics evaluated.ConclusionsFCNNs have promising potential in the analysis and segmentation of OC and OP video-endoscopic images. All tested FCNN architectures demonstrated satisfying outcomes in terms of diagnostic accuracy. The inference time of the processing networks were particularly short, ranging between 14 and 115 ms, thus showing the possibility for real-time application.
Hypereosinophilia in Solid Tumors—Case Report and Clinical Review
Authors: Zalewska Ewa , Obołończyk Łukasz , Sworczak Krzysztof 
Published: March 2021

BackgroundRenal cell cancer may cause various paraneoplastic syndromes; however, paraneoplastic hypereosinophilia occurs exceedingly rare. Thus far, only two cases of clear cell renal cell carcinoma (CCRCC) associated with hypereosinophilia have been reported. In this paper, we present a case of paraneoplastic hypereosinophilia associated with renal cell carcinoma and a review of the reported cases of hypereosinophilia in solid tumors.MethodsThe review is based on an electronic literature search performed in the PubMed database in September 2020 with the following key terms: eosinophilia &amp; neoplasm; eosinophilia &amp; cancer; eosinophilia &amp; paraneoplastic syndrome. Papers were included based on screening the titles and/or abstracts. We also included the case of our patient in the analysis.Case presentationA 68-year-old Caucasian female patient with recurrent CCRCC was admitted to our Clinic for exacerbating dyspnea and chest and right upper abdominal pain, accompanied by confusion. Preliminary blood tests showed an increased white blood cell count of 40,770/μl, and an increased eosinophil count of 6,530/μl indicating eosinophilia. Several tests were carried out to rule out the noncancer causes of hypereosinophilia. The temporal appearance of eosinophilia and the recurrence of CCRCC without any other apparent potential causes led to the diagnosis of paraneoplastic hypereosinophilia. Despite treating with high doses of corticosteroids, only a transient decrement in eosinophil count was observed along with further deterioration of the patient’s condition. The patient succumbed to the disease 6 months following the tumor surgery and 2 months after the diagnosis of hypereosinophilia and tumor recurrence.ConclusionOur observations are in agreement with the majority of reports showing that the occurrence of eosinophilia following tumor resection may indicate a poor prognosis, tumor recurrence, and rapid disease progression.
Discrepancies in the Time Course of Sleep Stage Dynamics, Electroencephalographic Activity and Heart Rate Variability Over Sleep Cycles in the Adaptation Night in Healthy Young Adults
Authors: Shirota Ai , Kamimura Mayo , Kishi Akifumi , Adachi Hiroyoshi , Taniike Masako , Kato Takafumi 
Published: March 2021

ObjectiveThe aim of the present study was to characterize the cyclic sleep processes of sleep-stage dynamics, cortical activity, and heart rate variability during sleep in the adaptation night in healthy young adults.MethodsSeventy-four healthy adults participated in polysomnographic recordings on two consecutive nights. Conventional sleep variables were assessed according to standard criteria. Sleep-stage continuity and dynamics were evaluated by sleep runs and transitions, respectively. These variables were compared between the two nights. Electroencephalographic and cardiac activities were subjected to frequency domain analyses. Cycle-by-cycle analysis was performed for the above variables in 34 subjects with four sleep cycles and compared between the two nights.ResultsConventional sleep variables reflected lower sleep quality in the adaptation night than in the experimental night. Bouts of stage N1 and stage N2 were shorter, and bouts of stage Wake were longer in the adaptation night than in the experimental night, but there was no difference in stage N3 or stage REM. The normalized transition probability from stage N2 to stage N1 was higher and that from stage N2 to N3 was lower in the adaptation night, whereas that from stage N3 to other stages did not differ between the nights. Cycle-by-cycle analysis revealed that sleep-stage distribution and cortical beta EEG power differed between the two nights in the first sleep cycle. However, the HF amplitude of the heart rate variability was lower over the four sleep cycles in the adaptation night than in the experimental night.ConclusionThe results suggest the distinct vulnerability of the autonomic adaptation processes within the central nervous system in young healthy subjects while sleeping in a sleep laboratory for the first time.
Deep Brain Stimulation for Obsessive-Compulsive Disorder: Real World Experience Post-FDA-Humanitarian Use Device Approval
Authors: Kahn Lora , Sutton Brianne , Winston Helena R. , Abosch Aviva , Thompson John A. , Davis Rachel A. 
Published: March 2021

Background: While case series have established the efficacy of deep brain stimulation (DBS) in treating obsessive-compulsive disorder (OCD), it has been our experience that few OCD patients present without comorbidities that affect outcomes associated with DBS treatment. Here we present our experience with DBS therapy for OCD in patients who all have comorbid disease, together with the results of our programming strategies.Methods: For this case series, we assessed five patients who underwent ventral capsule/ventral striatum (VC/VS) DBS for OCD between 2015 and 2019 at the University of Colorado Hospital. Every patient in this cohort exhibited comorbidities, including substance use disorders, eating disorder, tic disorder, and autism spectrum disorder. We conducted an IRB-approved, retrospective study of programming modifications and treatment response over the course of DBS therapy.Results: In addition to patients' subjective reports of improvement, we observed significant improvement in the Yale-Brown Obsessive-Compulsive Scale (44%), the Montgomery-Asberg Depression Rating Scale (53%), the Quality of Life Enjoyment and Satisfaction Questionnaire (27%), and the Hamilton Anxiety Rating scales (34.9%) following DBS. With respect to co-morbid disease, there was a significant improvement in a patient with tic disorder's Total Tic Severity Score (TTSS) (p = 0.005).Conclusions: DBS remains an efficacious tool for the treatment of OCD, even in patients with significant comorbidities in whom DBS has not previously been investigated. Efficacious treatment results not only from the accurate placement of the electrodes by the surgeon but also from programming by the psychiatrist.
Abordaje fisioterapéutico de las alteraciones funcionales del complejo articular del hombro debido a tratamientos oncológicos en cáncer de mama
Authors: Araya-Medrano María Gabriela 
Published: March 2021

Introducción: el cáncer de mama (CaM) es uno de los más frecuentes, posee una alta tasa de supervivencia. Los sobrevivientes no solo deben enfrentar la enfermedad y secuelas, sino también, los efectos secundarios de tratamientos oncológicos. El objetivo de esta revisión fue establecer las intervenciones fisioterapéuticas seguras y efectivas para abordar las alteraciones funcionales del complejo articular del Hombro (CAH) que comprometen el rango de movilidad articular (ROM) ipsilateral en mujeres con CaM sometidas a tratamientos oncológicos (cirugía, quimioterapia, radioterapia). Metodología: estudio de revisión bibliográfica narrativa. Se consultaron recursos digitales como PubMed, LILACS, SciELO, Elsevier, RefSeek, Google Académico, Dialnet, Academia, Base, Springer Link, ERIC y Redalyc como fuente de documentos publicados (libros, tesis, artículos científicos). Se utilizaron los descriptores neoplasias de la mama OR radioterapia OR quimioterapia OR mastectomía AND articulación del hombro OR dolor de hombro OR lesiones de hombro, AND fisioterapia OR medicina física OR rehabilitación. Se incluyen documentos publicados durante los últimos 20 años, en español, inglés y portugués. Considerando la evidencia publicada, se proponen algoritmos de intervención fisioterapéutica en la limitación funcional del CAH asociada a tratamiento para el CaM. Resultados: conocidas las principales limitaciones del ROM del CAH en CaM, se establecen las modalidades fisioterapéuticas con respaldo en evidencia científica, para recuperar el ROM y la funcionabilidad del CAH. Algunas de estas son estímulos eléctricos, termoterapia (superficial y profunda), cinesiterapia, fisioterapia invasiva, vendaje neuromuscular y terapia manual. Conclusión: las mujeres con CaM sometidas a tratamientos oncológicos ven afectado el ROM del CAH. La fisioterapia ayuda a mitigar estas secuelas.
Daya Tarik dan Eksistensi Komunikasi Dinas Komunikasi dan Informatika Provinsi Jawa Barat Dalam Pencegahan Penyebaran Berita Hoaka
Authors: Dewi Rahma , Kurniati Poni Sukaesih 
Published: March 2021

Penyebaran berita hoaks menjadi satu masalah berkelanjutan di Provinsi Jawa Barat karena masih banyaknya bertebaran berita hoaks. Tujuan dari pembuatan jurnal ini untuk mengetahui daya tarik dan eksistensi komunikasi Dinas Komunikasi dan Informatika Provinsi Jawa Barat dalam pencegahan penyebaran berita hoaks. metode yang digunakan dalam pembuatan jurnal ini adalah metode deskriptif dengan pendekatan kualitatif. Hasil dari penelitian ini adalah Dinas Komunikasi dan Informatika Provinsi Jawa Barat dalam daya tarik dan eksistensi komunikasi belum maksimal sehingga belum dapat menekan angka penyebaran berita hoaks di Jawa Barat. Namun, dengan strategi yang digunakan lebih mengutamakan media online mengingat masyarakat sudah modern hal ini dapat menjadi penunjang untuk menekan angka penyebaran berita hoaks bahkan meniadakan berita hoaks di Provinsi Jawa Barat
A Flexible Laboratory Exercise Introducing Practical Aspects of Mean Squared Displacement
Authors: Mantilla Alexander B. C. , Kuwada Nathan J. 
Published: March 2021

ABSTRACT
Mean squared displacement is a standard biophysical tool for characterizing the motion of particles in a thermally dominated environment, yet it is rarely formally introduced or discussed in undergraduate curriculum. Here, we provide a flexible and adaptable experimental or computational lab activity that provides a practical introduction to mean squared displacement and anomalous diffusion that includes optional experimental protocols and computational simulation techniques for data collection and discusses a variety of analysis techniques. This lab activity has been implemented both face-to-face and completely online and provides crucial experience in important research techniques, helping to bridge traditional undergraduate curriculum and modern biophysics research.
Faktor-Faktor Fundamental, Kondisi Makro Ekonomi dan Return Saham Perusahaan Pertambangan di Bursa Efek Indonesia
Authors: Sailendra Sailendra , Suratno Suratno 
Published: March 2021

A B S T R A C T
The main goal is to get investors to invest a high return. The mining company is an industry sector that gives investors hope to get high returns because the sector is undergoing a lot of changes in regulation since 2008. The government has tried to protect the export of raw materials mining and requires employers to process before being exported. Macroeconomic conditions and fundamental factor is that many factors affect stock prices. This study aimed to prove the effect of fundamental factors and macroeconomic conditions toward stock returns on mining companies. The results showed that there are significant fundamental factors and macroeconomic conditions toward stock returns. Fundamental factors that affect the return is the ratio of price to book value, while the macro-economic conditions which proved to affect the return is inflation.
A B S T R A K
Tujuan utama investor berinvestasi adalah mendapatkan return yang tinggi. Perusahaan tambang merupakan sektor industri yang memberikan harapan investor untuk mendapatkan return tinggi karena sektor ini mengalami banyak perubahan regulasi sejak tahun 2008. Pemerintah berupaya memproteksi ekspor bahan mentah tambang dan mewajibkan pengusaha untuk mengolahnya sebelum diekspor. Kondisi ekonomi makro dan faktor fundamental merupakan faktor yang banyak mempengaruhi harga saham. Penelitian ini bertujuan untuk membuktikan pengaruh faktor fundamental dan kondisi ekonomi makro terhadap return saham pada perusahaan tambang. Hasil penelitian adalah terdapat pengaruh faktor fundamental dan kondisi ekonomi makro terhadap return saham. Faktor fundamental yang ditemukan berpengaruh adalah rasio price to book value, sedangkan kondisi ekonomi makro yang terbukti berpengaruh adalah inflasi.
JEL Classification: G14, F62
Determinan Price to Book Value Perusahaan Manufaktur
Authors: Abdurrakhman Abdurrakhman 
Published: March 2021

A B S T R A C T
This study is aimed to test the influence of Current ratio (CR), Return on equity (ROE), Total assets turnover (TATO), and Size towards Price to book value (PBV). Samples are 114 firm firm years data of consumer goods listed companies in Indonesia Stock Exchange (IDX) during the period of 2006-2011 Analysis technique of data used multi linear regression of ordinary least square. This indicate that the available data has fulfilled the prerequisite to use multi-linier regression model. This research demonstrated that ROE and Size partially have significant influence towards the PBV. On the contrary, CR and TATO partially have no significant influence towards PBV. Simultaneously, CR, ROE, TATO, and the size has significant influence towards PBV of Consumer goods companies in IDX during the period of 2006.
A B S T R A K
Penelitian ini bertujuan untuk menguji pengaruh Rasio Current (CR), Return on equity (ROE), Total omset aset (TATO), dan Ukuran menuju Harga terhadap nilai buku (PBV). Sampel adalah 114 data tahun perusahaan consumer goods di Bursa Efek Indonesia (BEI) tercatat selama periode 2006-2011. Teknik analisis data menggunakan regresi linier multi biasa setidaknya persegi. Ini menunjukkan bahwa data yang tersedia telah memenuhi syarat untuk menggunakan model regresi multi-linier. Penelitian ini menunjukkan bahwa ROE dan Ukuran parsial memiliki pengaruh yang signifikan terhadap PBV. Sebaliknya, CR dan TATO sebagian tidak memiliki pengaruh yang signifikan terhadap PBV. Secara bersamaan, CR, ROE, TATO, dan ukuran memiliki pengaruh signifikan terhadap PBV perusahaan barang konsumen di BEI selama periode 2006.
JEL Classification: M40, O16