bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social Connections and Homeless’ People Views on them
Authors: Zlokazov Kirill , Ancheva Ivanina 
Published: October 2021

Introduction. The significance of social connections is due to diverse and crucial impact of environment to human life. The study of social connections enables to identify a person’s living standard and wellbeing. Addressing homeless people means better awareness and the opportunity to organize psychological assistance to them as well as to clarify the issue of social ties formation.
The study aims to review the theoretical concept of personal social connections and to analyze the homeless’ subjective views on their state.
The research tasks are to review a social connections structure; to carry out research on the homeless’ social connections and to analyze the characteristics of these ties.
Methodology. The social-subjective approach to social interaction is the key methodology of the study. It enables to form a concept of the homeless’ ties with other people and build the model of their social interaction. The advantage of the approach is the possibility to research the social ties of the homeless, to gather data about the parameters of these connections, to understand how the homeless perceive people around them, the society and themselves.
The main method of the study was the self-report. The survey on quantitative and qualitative characteristics of social connections of the homeless as well as the questionnaire on the key parameters of the person’s interaction with society (getting support from the social environment, self – assessment of the interaction, the impact on social environment) were conducted. The data were processed by descriptive statistics and Kruskal–Wallis H test.
The sample of the study consisted of 197 participants aged 45–50. The majority of the sample (80%) was male. The research procedure. We compared the subjective awareness of social interaction of the homeless and people who have
accommodation.
Our results show the decrease of social impact on the person among the homeless. It is determined by low rapport, poor interpersonal communication, low authority and low reference as well as little value of social environment. The research reveals that the homeless make an improper evaluation of their interaction with social environment. That results in low assessment of social support, underestimation of their own impact on the environment and overestimation of their ability to interact.
Scientific novelty. The findings of the study expand the understanding of the state of homelessness. They reveal socialpsychological characteristics of the homeless interaction with the environment as well as specifies the concept of socialperceptive ideas formed during these interactions with the environment.
Practical significance. This study emphasizes the necessity of forming the homeless social skills, indicates the issues of psychological prevention in counseling and providing social assistance to this category of citizens.
The Relationship between Proinflammatory Cytokines, Trait Mindfulness, and Psychological Well-Being in Rheumatoid Arthritis
Authors: Krishan Tewatia  , Dinesh N  , Revathi P Shenoy  , Shivashankara K N  
Published: October 2021

Background: Rheumatoid arthritis(RA) is an autoimmune disease in which the body’s immune systemstarts attacking its own cells especially, joints. Individuals with RA are 3 times more susceptible todepression and anxiety. Mindfulness-based interventions have been found efficacious in decreasingdepressive symptoms and increasing psychological well-being(PWB) in this population, but therelationship between trait mindfulness and PWB with proinflammatory cytokines implicated in RA hasnot been explored to date.
Background: Rheumatoid arthritis(RA) is an autoimmune disease in which the body’s immune systemstarts attacking its own cells especially, joints. Individuals with RA are 3 times more susceptible todepression and anxiety. Mindfulness-based interventions have been found efficacious in decreasingdepressive symptoms and increasing psychological well-being(PWB) in this population, but therelationship between trait mindfulness and PWB with proinflammatory cytokines implicated in RA hasnot been explored to date.Objective: This study aimed to understand the relationship between proinflammatory cytokines, traitmindfulness, and psychological well-being in rheumatoid arthritis patients.Method: The study consisted of a total of 16 individuals from the 45-75 years age group who havebeen diagnosed with RA, taking treatment from Kasturba Medical College, Manipal. Proinflammatorycytokines in saliva, IL-6 and TNF levels were measured using an ELISA kit, and scales wereadministered to measure trait mindfulness, psychological well-being, and functioning. Descriptiveanalysis was done to study the relationship between the variables.Results: A significant increase in IL-6 levels were observed in the present study, while TNF- levelswere within normal limits. 50% of the participants reported severe impairment and 75% reporteddepressive symptoms. These results provided evidence of a strong correlation between IL-6 levelsand depression. There was a strong positive correlation between trait mindfulness and psychologicalwell-being, . Trait mindfulness however had a moderately negative correlation withdepressive symptoms and disability. Moreover, the relationship between psychological well-being anddepressive symptoms and disability was not significant. The relationship between depressive symptomsand disability was highly significant, Discussion and Conclusion: People with RA experience difficulty carrying out everyday tasks andtend to suffer from depression. However, people who score high on Mindfulness and PWB experienceless depression and face less interference in their daily activities. Thus, interventions that promotemindfulness practice and psychological well-being may prove to be effective in decreasing depressivesymptoms in RA patients as well as proinflammatory cytokines.
A new species of Cheironitis van Lansberge, 1875 from Jordan (Coleoptera, Scarabaeidae, Onitini)
Authors: Coppo Paul , Montreuil Olivier 
Published: October 2021

The genus Cheironitis van Lansberge, 1875, currently contains 23 species from the Old World. During a survey for dung beetles in Jordan, specimens of an undescribed species were collected at the historical site of Petra.
A new species of Cheironitis (C. petraensis sp. n.) is described from the historical site of Petra, Jordan, illustrated and compared with its most closely related species. This new species is reminiscent of the African species of Cheironitis living in savannahs and could represent a relictual species of the mid-Holocene climatic optimum.
Editorial
Authors: Gütl Christian 
Published: October 2021

It gives me great pleasure to announce the sixth regular issue of 2021. All this is only possible thanks to the great support of the J.UCS community. Therefore, I would like to thank all the authors for their sound research and the editorial board for the highly valuable reviews and suggestions for improvement. These contributions together with the generous support of the consortium members sustain the quality of our journal.
We are always interested in receiving high quality proposals for special issues on new topics and emerging trends. Please consider yourself and encourage your colleagues to submit high quality articles to our journal. I am also still looking to expand our editorial board: If you are a tenured associate professor or higher and have a good publication record, please feel free to apply to join our editorial board.
In this regular issue, I am very pleased to introduce six accepted papers contributed by 17 authors from six different countries.
Rochdi Boudjehem and Yacine Lafifi from Algeria outline their research on how to identify and assist struggling learners by monitoring and analyzing their behavior within the e-learning environment. Abdelouafi Ikidid, Abdelaziz El Fazziki and Mohammed Sadgal from Morocco introduce a fuzzy logic-based multi-agent system for traffic light control at a signalized intersection by acting on the length and sequence of traffic light phases to favor priority flows and make traffic flow more smoothly at an isolated intersection and for the entire network with multiple intersections. Andrea Lezcano Airaldi, Jorge Andr&eacute;s Diaz-Pace and Emanuel Irraz&aacute;bal from Argentina conducted a case study to evaluate the benefits of incorporating data-driven storytelling into the development of a software system to support decision-making in crisis settings. Jos&eacute; Monteiro, Maria Bernardo, Mafalda Ferreira, and T&acirc;nia Rocha from Portugal discuss their study of quality aspects of e-government information with the goal of better understanding which of these attributes are most valued from the users&rsquo; perspective when evaluating content provided by government websites. Ricardo P&eacute;rez- Castillo and Mario Piattini from Spain outline their study on how the evolution of the development effort influences the code quality, which was analyzed on 13 open source projects. Hamda Slimi, Ibrahim Bounhas and Yahya Slimani from Tunisia discuss their approach, which aims to detect emerging and unseen rumors on Twitter by adapting a pre-trained language model, namely RoBERTa, to the task of rumor detection.
Facteurs associés à la résilience des étudiants de Licence en sciences infirmières au Liban : une étude exploratoire descriptive
Authors: Narchi Séoud Joëlle 
Published: October 2021

Introduction : la pression des études et des stages effectués durant la formation pourrait affecter la santé et les résultats académiques des étudiants en sciences infirmières. Cependant, certains étudiants réagissent positivement au stress et sont considérés comme des personnes résilientes puisqu’ils ne font pas seulement face au stress mais rebondissent pour atteindre les défis qu’ils ont fixés. Les études ont identifié des facteurs académiques, cliniques, personnels et sociaux en lien avec la résilience des étudiants en sciences infirmières. Méthode : cette étude a pour but d’explorer les facteurs associés à la résilience des étudiants de Licence en sciences infirmières d’une université à Beyrouth. La collecte des données s’est déroulée à partir d’un questionnaire structuré, qui regroupe quatre instruments de mesure, et le profil démographique et académique des étudiants. Résultats : plus de la moitié des étudiants sont résilients, et parmi tous les facteurs, seul le sentiment d’auto-efficacité est associé significativement à la résilience. Discussion : cette étude a permis une meilleure compréhension du phénomène de la résilience des étudiants en sciences infirmières au Liban. Elle offre des pistes concrètes pour l’intervention infirmière favorisant la rétention des étudiants dans la formation infirmière.
Prévention des chutes chez les personnes âgées fragiles hospitalisées en court séjour : utilisation des chaussettes antidérapantes. Une revue systématique de littérature
Authors: Pelliard Thomas , Brika Marine , Rulleau Thomas 
Published: October 2021

Introduction : les chutes chez les personnes âgées fragiles hospitalisées sont un phénomène majeur et préoccupant au quotidien. Contexte : les chaussages inadéquats, fréquemment observés au sein de cette population, constituent l’un des principaux facteurs de risques. Plusieurs hôpitaux utilisent des chaussettes antidérapantes comme moyen préventif. Dans le contexte de la médecine basée sur les preuves, il semble nécessaire de vérifier l’existence de données probantes concernant leur efficacité. Objectif : cet article vise à statuer sur l’efficacité préventive des chaussettes antidérapantes. Méthode : cinq bases de données ont été investiguées (PubMed, PEDro, Cochrane, ScienceDirect et Google Scholar). Les critères d’éligibilité (PICO) incluent les patients âgés hospitalisés. Résultats : sept études ont été incluses. Les chaussettes antidérapantes montrent un effet préventif pour diminuer les récidives de chutes ( p = 0.009) ou la prévalence des chutes en lien avec l’incontinence urinaire. Discussion : plusieurs études concluent sur la plus-value des chaussettes antidérapantes comparativement aux chaussettes classiques ou aux pantoufles. Les limites inhérentes aux études sélectionnées sont considérées dans l’élaboration des conclusions. Conclusion : un chaussage considéré comme sécuritaire par les thérapeutes et sécurisant par le patient constitue l’option la plus recommandée actuellement. Des études cliniques complémentaires sont nécessaires pour étayer notre conclusion.
The relationship of serum growth differentiating factor 15 with hepcidin in posttransplant adult Egyptian patients and its prognostic significance
Authors: ElRazzaz Mostafa K.H. , Azzazi Mohamed O. , AlAfifi Amal M. , Hegab Hany M. , El-Ghammaz Amro M.S. , Shazly Mohammad Abd-Allah 
Published: October 2021

Background
Hepcidin is a small peptide that is produced in the liver that is most likely the major regulator of iron. Based upon the importance of iron, multiple mechanisms exist for the regulation of hepcidin. Iron levels, inflammation, erythropoiesis, and the combined effects of several proteins expressed on hepatocyte membranes are involved. Growth differentiation factor 15 (GDF15) is a member of the transforming growth factor-b. GDF15 expression level is usually low in resting cells but may be substantially increased following response to diverse cellular stress signals, such as hypoxia, inflammation, acute tissue injury, and during cancer progression.

Aim
The aim was to assess the relationship of serum GDF15 with hepcidin in posttransplant adult Egyptian patients as an assessment for iron overload and their relationship with posttransplantation complications.

Patients and methods
Serum GDF15 and hepcidin were measured using enzyme-linked immunosorbent assay in 45 postallogenic (23 patients) and autologous (22 patients) bone marrow transplanted patients 1 year after transplantation in comparison with 15 healthy controls recruited from the bone marrow transplantation unit, Ain Shams University Hospitals.

Results
Serum level of GDF15 and hepcidin level were elevated 1 year after allogenic and autologous transplantation patients in comparison with control group, with a statistically significant difference between patients and controls (P<0.001). GDF15 and hepcidin were positively correlated with ferritin level (P<0.001). GDF15 and ferritin were positively correlated with acute graft-versus-host disease (GVHD) and chronic GVHD (P=0.004 and 0.002, respectively), but hepcidin did not show any significant correlation with acute GVHD (P=0.110). Moreover, GDF15, hepcidin and ferritin were positively correlated with serum levels of alanine transferase and aspartate transferase in both autologous and allogenic transplanted patients. However, GDF15, hepcidin, and ferritin were not correlated with bacterial or viral infections in both allogenic and autologous groups of patients.

Conclusion
Both GDF15 and hepcidin are useful biomarkers for iron overload in late postallogenic and autologous bone marrow transplantation, and both can be used as a predictor for posttransplantation complications.
Role of circulating myeloid-derived suppressor cells in pathogenesis of immune thrombocytopenia in children and adolescents
Authors: Andrawes Nevine G. , Hamza Mohamed T. , Bayomi Fatma A. , Abd Elraheem Ali Heba G. 
Published: October 2021

Context
Regulatory T cells have an immunosuppressive function on T-cell activation. They are involved in pathophysiology and treatment of immune thrombocytopenia (ITP). Circulating myeloid-derived suppressor cells (MDSCs) are involved in immune dysregulation in ITP.

Aim
To determine the mean level of MDSCs in acute, persistent, and chronic ITP and its effect on treatment modalities and prognosis.

Patients and methods
A total of 41 patients with ITP were recruited from the pediatric hematology clinic of Ain Shams University. They were classified into acute, persistent, and chronic and were compared with 20 age-matched and sex-matched healthy controls. All patients were subjected to history taking with emphasis on age of presentation, disease duration, and treatment modalities, as well as thorough clinical examination. Mean values of C-reactive protein, alanine aminotransferase, and serum creatinine were collected from the patients’ files. All study participants underwent complete blood count (Coulter) and MDSCs by flow cytometry. Secondary thrombocytopenia was excluded.

Results
Acute ITP was detected in 29%, 24% had persistent, and 46% had chronic ITP. Their age ranged from 1 to 16 years at the study entry, and 51.2% were male. Active disease was found in 58.5%, whereas 41.4% in remission. No treatment was offered to 53%, whereas 24% of patients were on steroids. MDSCs decreased significantly in patients with ITP compared with the control group (P<0.001), whereas there was no significant difference among the patient groups regarding MDSCs level (P=0.325) or with different treatment modalities.

Conclusion
Reduced numbers of MDSCs play a role in pathogenesis of ITP. Yet, MDSCs did not differ according to disease duration or treatment modalities.
Comparative study between different alloadsorption techniques in warm autoimmune hemolytic anemia
Authors: Emam Noha A.M. , Ezzelarab Soha , Hassan Noha B. , El Saeyed Heba N. , Nabih Nermeen A. , Hamed Gehan M. 
Published: October 2021

Background
Autoantibodies in patients with autoimmune hemolytic anemia (AIHA) are encountered with difficulties in ABO grouping and cross-matching; moreover, they may mask the presence of alloantibodies, leading to hemolytic transfusion reaction. Therefore, an efficient and time-saving method is required to detect alloantibodies underlying autoantibodies for safe transfusion in AIHA.

Aim
To compare the efficiency of different alloadsorption techniques in detection of alloantibodies after complete removal of autoantibodies.

Patients and methods
A total of 70 patients with warm AIHA were enrolled in this study; antibody screening was done by using screening cells (I+II+III cells). Allogenic adsorption was performed using conventional, polyethylene glycol (PEG), and low ionic strength solution (LISS)/papain methods followed by rescreening to ensure the adsorption of the autoantibodies, and whenever screening test revealed the presence of alloantibodies, antibody identification was done. Antibody identification and cross-matching with phenotyped red cells were done by the plasma obtained with this method. The best adsorption method was chosen depending on its ability to preserve the alloantibody.

Results
A significant difference was found among the three alloadsorption methods regarding number of alloadsorptions and time for complete autoantibodies removal. PEG showed the lowest mean number of alloadsorptions (2.6±1.2) followed by LISS/papain (3.1±1.5) compared with the conventional method (3.7±1.4) (P<0.001). Regarding the time, PEG was the most rapid method (38.6±17.6 min) followed by LISS/papain (45.9±22.8 min) and then the conventional method (110.1±14.4 min) (P<0.001). However, no significant difference was found between PEG and LISS/papain (P=0.014). Alloantibodies were detected in 35% of cases, with predominance of anti-Rh system (61%), mainly anti-c and anti-E. Alloantibodies belonging to Rh and Kidd were best identified in adsorbed plasma by LISS/papain in comparison with PEG and the conventional techniques.

Conclusion
Among the evaluated methods, LISS/papain displayed the highest diagnostic accuracy, sensitivity, and specificity of alloantibody detection. Compared with the conventional method, LISS/papain and PEG minimized the time and number of alloadsorptions, enhancing turnaround time and reducing the labor of pretransfusion testing in AIHA.
Seropositive coronavirus disease 2019 detection among apparently healthy voluntary blood donors
Authors: Abdelmaksoud Sahar S. , Youssef Mariam K. , Aboulmagd Mahmoud M. , Abdelmaksoud Mariam F. 
Published: October 2021

Background
Despite the prevailing pandemic of coronavirus disease 2019, there are no recommendations available yet for serological screening of apparently healthy asymptomatic blood donors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies.

Objective
To explore the seropositivity for SARS-CoV-2 antibodies in serum samples of a group of randomly selected Egyptian voluntary blood donors who met the eligibility criteria for blood donation as a preliminary step to catch apparently healthy asymptomatic participants who constitute an important source of viral spread in the community.

Patients and methods
The first phase of our study design plan included 100 anonymous serum samples of a group of voluntary blood donors who donated blood at Ain-Shams University Hospitals’ blood bank during the period from the second week of September to the end of October 2020. After completion of the steps of donation, donors’ stored serum samples were screened for SARS-CoV-2-specific immunoglobulin (Ig)M and IgG antibodies. The next phase of our study design plan is intended to include larger samples of known apparently healthy asymptomatic blood donors in an attempt to reach seropositive patients to confirm the results by PCR and validate the testing.

Results
A total of 100 anonymous serum samples were included in the study. Eleven (11%) samples were reactive for viral specific IgM antibodies, and 38 (38%) samples were reactive for viral specific IgG antibodies.

Conclusion
As the ongoing pandemic of coronavirus disease 2019 is continuing to demand urgent attention, screening of all asymptomatic apparently healthy voluntary blood donors for SARS-CoV-2 antibodies followed by viral RNA detection by PCR in seropositive donors could abort viral spread to others in blood centers and eventually to the rest of the community.
Severity and Prevalence of Sperm DNA Damage among Infertile Males at a Tertiary Hospital, North Central, Nigeria
Authors: Oladosu Waliu Olatunbosun , Biliaminu Sikiru Abayomi , Abdulazeez Musbau Ishola , Jimoh Saheed Olanrewaju , Ajose Olabamiji Abiodun , Okesina Adekunle Bashiru 
Published: October 2021

Context:
Seminal fluid analysis (SFA) is the most important investigative tool for evaluation of male infertility. However, it is limited in detecting causes of sperm abnormalities while some individuals with normal SFA are still considered infertile. Evaluating sperm deoxyribonucleic acid (DNA) integrity as an ancillary investigative tool to SFA will enhance the investigation of infertility.

Aims:
The aim is to assess the prevalence and severity of sperm DNA damage based on semen level of 8-hydroxydeoxyguanosine (8-OHdG) in males with and without abnormal SFA.

Settings and Design:
This was a descriptive cross-sectional study of 120 males with at least one SFA parameter abnormalities as test controls and 120 normal controls.

Subjects and Methods:
Seminal 8-OHDG was assayed as a marker of sperm DNA damage using ELISA method.

Statistical Analysis Used:
Normally distributed data were expressed as mean ± standard deviation otherwise expressed as median and interquartile range.

Results:
The mean ages of subjects and controls were 35.84 ± 6.0 vs. 36.22 ± 7.56 years. The mean seminal 8-OHDG was significantly higher among subjects than among controls (15.21 ± 3.80 ng/ml vs. 12.45 ± 4.0 ng/ml, P = 0.015). The reference value of seminal 8-OHDG obtained in this study was 4.45–20.45 ng/ml and the prevalence of sperm DNA damage among subjects compared to controls was 10.8% versus 3.3%, P = 0.024. Severe DNA damage corresponding to sperm DNA fragmentation index of >30% was 3.3% in subjects and was not present in any male partner in the control group. Significant sperm DNA damage was also associated with reduced sperm count (P = 0.043), while its association with reduced sperm motility was not statistically significant in this study.

Conclusions:
The prevalence and severity of sperm DNA damage were more significant among males with, than those without, abnormal SFA parameters.