bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengembangan Metode Pendidikan Agama Islam Berbasis Kisah Qurani Sebagai Media Penanaman Karakter Islami
Authors: Latif Muhammad Abdul 
Published: June 2021

<p>Characters that are often discussed as part of educational goals are still overlapping. The values of the characters that want to be instilled are still not raised, and there needs to be developed. The value of Islamic characters can be taken from the previous Saheeh stories told directly by the Prophet Muhammad. Researchers tried to explore other Islamic characters by using descriptive methods using the library research approach. The primary data source of this research is a book by Umar Sulaiman al-Asyqor, titled The Stories of Shahih in the Qur'an and As-Sunnah, curriculum 2013 pai elementary school subjects, related books, thesis, and articles relevant to the theme studied. This study found many Islamic characters that have not been listed in the competency standards of the PAI 2013 curriculum. Of the 18 character values and 61 characters determined, there are still character values that have not been listed if they are based on Islamic values. Among the characters that do not exist and need to be used as development are: tawhid, analytical, exemplary, prudence, qana'ah, produce work, firm, admit mistakes, obey, love animals, benefactors, shame, hospitality, meticulous, cooperation, help, curiosity, rukun, good guess, tabligh, fathanah, and straightforward. </p><p class="16aJudulAbstrak"><strong>Abstrak</strong></p><p class="16cKataKunci">Karakter yang sering dibahas sebagai bagian dari tujuan pendidikan masih mengalami timpang tindih. Nilai-nilai karakter yang ingin ditanamkan masih belum dimunculkan serta perlu adanya pengembangan. Nilai karakter islami dapat diambil dari kisah-kisah shahih terdahulu yang diceritakan langsung oleh Rasulullah Muhammad saw. Peneliti mencoba menggali lebih jauh karakter Islami dengan menggunakan metode deskriptif dengan menggunakan pendekatan library research. Sumber data utama dari penelitian ini adalah buku karya Umar Sulaiman al-Asyqor, dengan judul Kisah-Kisah Shahih dalam Al-Qur’an dan As-Sunnah, kurikulum 2013 mata pelajaran PAI sekolah dasar, buku-buku terkait, tesis, serta artikel yang relevan dengan tema yang diteliti. Hasil penelitian ini menemukan banyak karakter Islami yang belum tercantum dalam standar kompetensi kurikulum PAI 2013. Dari 18 nilai karakter dan 61 karakter yang sudah ditentukan, masih ada nilai karakter yang belum tercantum jika dilandaskan kepada nilai-nilai keislaman. Di antara karakter yang belum ada dan perlu dijadikan pengembangan adalah: tauhid, analitis, teladan, kehati-hatian, qana’ah, menghasilkan karya, teguh, mengakui kesalahan, taat, menyayangi hewan, dermawan, rasa malu, silaturahmi, teliti, kerja sama, tolong-menolong, rasa ingin tahu, rukun, baik sangka, tabligh, fathanah, dan sederhana.</p>
Kontribusi Persepsi Siswa tentang Jurusan Terhadap Motivasi Siswa dalam Belajar serta Implikasinya pada Program Bimbingan dan Konseling
Authors: Jumiarti Desri 
Published: June 2021

Motivasi adalah salah satu faktor yang menentukan keberhasilan siswa dalam belajar. Sedangkan pada sekolah kejuruan, persepsi siswa tentang jurusan yang mereka pilih diduga merupakan salah satu faktor yang akan mempengaruhi motivasi siswa dalam belajar. Persepsi siswa tentang jurusan yaitu bagaimana siswa menilai dan memahami jurusan yang ditempati. Beberapa hasil penelitian telah menjelaskan bahwa persepsi merupakan salah satu faktor internal yang cukup besar pengaruhnya terhadap keberhasilan belajar. Sehingga, tujuan dari penelitian ini adalah untuk mendeskripsikan bagaimana persepsi siswa tentang jurusan yang ditempatinya, serta mendeskripsikan motivasi siswa dalam belajar, selain itu untuk menguji kontribusi persepsi siswa tentang jurusan terhadap motivasi belajar siswa. Metode yang digunakan dalam penelitian ini adalah kuantitatif jenis deskriptif korelasional dan metode kualitatif. Adapun populasinya yaitu siswa kelas XI SMKN 1 Kota Solok yang berjumlah 580 siswa, sedangkan sampel penelitian berjumlah 237 siswa. Teknik yang digunakan dalam penelitain ini yaitu Proportional Statified Random Sampling. Instrumen yang digunakan adalah skala model Likert. Sedangkan analisis data dengan menggunakan statistik deskriptif dan regresi sederhana. Adapun temuan dari penelitian ini adalah : (1) persepsi siswa tentang jurusan yang ditempati rata-rata berada pada kategori positif, (2) motivasi belajar siswa berada pada kategori tinggi, dan (3) terdapat kontribusi yang signifikan antara persepsi siswa tentang jurusan terhadap motivasi belajar siswa. Adapun implikasi dari hasil penelitian ini dapat digunakan untuk menganalisis kebutuhan siswa sebagai penyempurnaan pembuatan program layanan bimbingan dan konseling di SMKN 1 Kota Solok.
ANXIETY RELATED TO ELDERLY SLEEP QUALITY
Authors: Zahroh Chilyatiz , Masnia Azizatul , Nadatien Ima , Winoto Priyo Mukti Pribadi 
Published: June 2021

Background: Elderly face various health problems that need immediate and integrated handling. With increasing age, there will be a decrease in body function in the elderly both physically, physiologically and psychologically. The mental health problem that often occurs in the elderly is feeling worried.
Objektif:: This study aims to analyze whether there is a relationship between anxiety levels and sleep quality among the elderly in Surabaya.
Methods: The design of this study was analytic correlation with the approach used cross-sectional. The population Is all elderly in the qoryah thoyyibah kenjeran Surabaya posyandu, which amounted to 44 elderly. The sampel size of this study was 40 respondents, probability sampling technique was simple random sampling, this study contained an independent variable of anxiety level while the dependent variable was sleep quality. data collection instrument using a questionnaire. The data were analyzed using the spearman rank correlation test with a value of a = 0,05.
Results: The results of research from 40 respondents showed that half (50%) experienced severe anxiety and almost half (47,5) had moderate sleep quality. Further analysis using the spearman rank test with a significance level of a= 0,05, the value of p=0.02 is obtained, which means p<a the Ho is rejected, which means that there is a relationship between the level of anxiety and the quality of sleep in the elderly at qoryah thoyyibah kenjeran Surabaya
Conclusions: The conclusion of this study is that there is relationship between anxiety and sleep quality in the elderly at qoryah thoyyibah kenjeran Surabaya posyandu. It is hoped that the result of this study can develop the ability of further researchers to conduct more specific research related to the relationship between anxiety levels and sleep quality in the elderly.
Recovery Room Efektif Menurunkan Kelelahan Kerja pada Pekerja di Bagian Laundry Rumah Sakit
Authors: Qosim Nanang , S Henry Setyawan , Setyaningsih Yuliani 
Published: June 2021

Suhu tinggi di bagian laundry Rumah Sakit menyebakan 60% pekerja merasakan kelelahan. Upaya yang dilakukan manajemen Rumah Sakit dalam mengatasi kelelahan kerja adalah disediakannya recovery room guna mempercepat proses pemulihan. Tujuan penelitian ini untuk menganalisis efektifitas recovery room dalam menurunkan kelelahan kerja, melihat pemanfaatan recovery room dan kendala yang dihadapi dalam pemanfaatannya. Desain penelitian yang digunakan adalah Quasi eksperimen, one group pre – posttest design dengan pendekatan cross sectional dan wawancara. Populasi dan sampel adalah seluruh pekerja di bagian laundry sejumlah 50 responden. Analisis data menggunakan uji beda Wilcoxon. Hasil penelitian menunjukkan terdapat perbedaan signifikan tingkat kelelahan kerja antara sebelum dan sesudah memanfaatkan recovery room yang ditunjukkan dengan penurunan nilai mean dari 336,7 (sebelum intervensi) menjadi 290,8 (setelah intervensi) dengan p value = 0,000 < α (0,05). Recovery room belum sepenuhnya dapat dimanfaatkan oleh semua pekerja karena keterbatasan tempat, kurangnya privasi dan persepsi pekerja bahwa istirahat dimanapun sama. Recovery room efektif menurunkan kelelahan kerja pekerja laundry di Rumah sakit. Diharapkan manajemen rumah sakit agar dapat memastikan pekerja dapat memanfaatkan recovery room dengan cara mangatur jadwal penggunaan recovery room, mengatur waktu istirahat, edukasi pentingnya memanfaatkan recovery room dan menambah kapasitas agar semua pekerja dapat mengakses recovery room dengan optimal.
Pengembangan Bahan Ajar Cerita Rakyat Berbasis Komik Untuk Penanaman Kemampuan Literasi Siswa Sekolah Dasar Kabupaten Rejang Lebong
Authors: Anggara Ahmad Yuda 
Published: June 2021

This research aimed to develop folklord teaching material based on comic and the effectifness in instilling elementary student literacy skill on Rejang Lebong. The research used research and development method (R&D). The subject on this research were the 5th grade student of elementary school number 85 on Rejang Lebong as control class, the 5th grade student of Al Latif Unggulan Aisyiyah on Rejang Lebong as first class experiment and the 5th grade student of elementary school number 10 on Rejamg Lebong as second experiment class. Based on result of this research and the explanation. In conclution that (1) the development of teaching material began with preliminary study through student and teacher interview. Then the interview result were adjusted to the theory and the observation become a draft model that would be validated by experts. Revised draft model would be tested in small scale and large scale.AFter that the final test product would be conducted by pretest and postest technique and the gain score would be analized. (2) folklore teaching material based on comic was effective to instill student literacy. g-score of the experiment class has 0.63 for kognitif aspect and 0.57 for psikomor aspect, while the g-score in control class has 0.16 for kognitif and psikomotor aspect.
Penerapan Model Guided Inquiry Pada Pembelajaran Tematik untuk Meningkatkan Aktivitas dan Hasil Belajar Siswa Kelas IVA SD Negeri 1 Bengkulu Tengah
Authors: Erzaita Renny Erzaita , Koto Irwan Koto , Djuwita Puspa Djuwita 
Published: June 2021

Pembelajaran tematik dengan model guided inquiry bertujuan untuk meningkatkan hasil belajar siswa dalam aspek afektif dan kognitif. Metode penelitian tindakan kelas (PTK) dilaksanakan dalam 3 siklus yang terdiri dari perencanaan, pelaksanaan, pengamatan dan refleksi. Penelitian dilakukan di kelas IVA SDN 1 Bengkulu Tengah yang terdiri dari 10 laki-laki dan 10 perempuan. Data diperoleh dari (1) pengamatan langsung kegiatan guru dalam pelaksanaan pengajaran model guided inquiry dan siswa dalam proses pembelajaran dengan guided inquiry dan (2) tes hasil belajar dalam aspek afektif dan kognitif. Data dianalisis menggunakan nilai rata-rata, ketuntasan belajar dan pengkategorian. Aktivitas guru siklus I mencapai kategori cukup, siklus II menjadi kategori baik dan siklus III meningkat dengan kategori sangat baik. Aktivitas siswa pada siklus I kategori kurang, siklus II menjadi kategori baik dan siklus III meningkat menjadi sangat baik. Hasil belajar siswa pada siklus I dengan rata-rata nilai 69,25, pada siklus II menjadi 84,75 dan meningkat lagi pada siklus III menjadi 88,75. Hasil belajar siswa secara individu pada siklus I dengan rata-rata 68,6, pada siklus II sebesar 74,75 dan pada siklus III lagi sebesar 81,85. Pada penilaian sikap spiritual dan sosial terjadi peningkatan persentase pada setiap siklusnya. Hasil penelitian ini menunjukkan bahwa dengan menerapkan model guided inquiry mampu meningkatkan proses belajar dan hasil belajar siswa.
Clinical Studies and Pre-clinical Animal Models on Facial Nerve Preservation, Reconstruction, and Regeneration Following Cerebellopontine Angle Tumor Surgery–A Systematic Review and Future Perspectives
Authors: Hostettler Isabel C. , Jayashankar Narayan , Bikis Christos , Wanderer Stefan , Nevzati Edin , Karuppiah Ravindran , Waran Vicknes , Kalbermatten Daniel , Mariani Luigi , Marbacher Serge , Guzman Raphael , Madduri Srinivas , Roethlisberger Michel 
Published: June 2021

Background and purpose: Tumorous lesions developing in the cerebellopontine angle (CPA) get into close contact with the 1st (cisternal) and 2nd (meatal) intra-arachnoidal portion of the facial nerve (FN). When surgical damage occurs, commonly known reconstruction strategies are often associated with poor functional recovery. This article aims to provide a systematic overview for translational research by establishing the current evidence on available clinical studies and experimental models reporting on intracranial FN injury.Methods: A systematic literature search of several databases (PubMed, EMBASE, Medline) was performed prior to July 2020. Suitable articles were selected based on predefined eligibility criteria following the Preferred Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) guidelines. Included clinical studies were reviewed and categorized according to the pathology and surgical resection strategy, and experimental studies according to the animal. For anatomical study purposes, perfusion-fixed adult New Zealand white rabbits were used for radiological high-resolution imaging and anatomical dissection of the CPA and periotic skull base.Results: One hundred forty four out of 166 included publications were clinical studies reporting on FN outcomes after CPA-tumor surgery in 19,136 patients. During CPA-tumor surgery, the specific vulnerability of the intracranial FN to stretching and compression more likely leads to neurapraxia or axonotmesis than neurotmesis. Severe FN palsy was reported in 7 to 15 % after vestibular schwannoma surgery, and 6% following the resection of CPA-meningioma. Twenty-two papers reported on experimental studies, out of which only 6 specifically used intracranial FN injury in a rodent (n = 4) or non-rodent model (n = 2). Rats and rabbits offer a feasible model for manipulation of the FN in the CPA, the latter was further confirmed in our study covering the radiological and anatomical analysis of perfusion fixed periotic bones.Conclusion: The particular anatomical and physiological features of the intracranial FN warrant a distinguishment of experimental models for intracranial FN injuries. New Zealand White rabbits might be a very cost-effective and valuable option to test new experimental approaches for intracranial FN regeneration. Flexible and bioactive biomaterials, commonly used in skull base surgery, endowed with trophic and topographical functions, should address the specific needs of intracranial FN injuries.
Bandgap Engineering and Near-Infrared-II Optical Properties of Monolayer MoS2: A First-Principle Study
Authors: Yang Ke , Liu Tianyu , Zhang Xiao-Dong 
Published: June 2021

The fluorescence-based optical imaging in the second near-infrared region (NIR-II, 1,000–1,700 nm) has broad applications in the biomedical field, but it is still difficult to find new NIR-II fluorescence materials in the two dimension. As a crucial characteristic of the electronic structure, the band structure determines the fundamental properties of two-dimensional materials, such as their optical excitations and electronic transportation. Therefore, we calculated the electronic structures and optical properties of different crystalline phases (1T phase and 2H phase) of pure monolayer MoS2 films and found that the 1T phase has better absorption and thus better fluorescence in the NIR-II window. However, its poor stability makes the 1T-phase MoS2 less useful in vivo bioimaging. By introducing vacancy defects and doping with foreign atoms, we successfully tuned the bandgap of the monolayer 2H-MoS2 and activated it in the NIR-II. Our results show that by engineering the vacancy defects, the bandgap of the 2H phase can be tailored to around 1 eV, and there are three candidates of vacancy structures that exhibit strong absorption in the NIR-II.
Bacillus amyloliquefaciens YN201732 Produces Lipopeptides With Promising Biocontrol Activity Against Fungal Pathogen Erysiphe cichoracearum
Authors: Jiao Rong , Cai Yongzhan , He Pengfei , Munir Shahzad , Li Xingyu , Wu Yixin , Wang Junwei , Xia Mengyuan , He Pengbo , Wang Ge , Yang Huanwen , Karunarathna Samantha C. , Xie Yan , He Yueqiu 
Published: June 2021

Bacillus amyloliquefaciens YN201732 is an endophytic bacteria with high biocontrol efficiency and broad-spectrum antimicrobial activities. In order to clarify the main active ingredients and their antifungal mechanisms against powdery mildew of tobacco, this study is focused on lipopeptide obtained through acid precipitation and organic solvent extraction. HPLC and LCMS-IT-TOF were used to separate and identify antimicrobial lipopeptides. Findings revealed that bacillomycin D plays an important role against surrogate fungal pathogen Fusarium solani. Synthetic pathways of sfp, bacillomycin D, and fengycin were separately disrupted. The sfp gene knockout mutant B. amyloliquefaciens YN201732M1 only showed minor antagonistic activity against F. solani. While Erysiphe cichoracearum spore germination was inhibited and pot experiments displayed a significant decrease in tobacco powdery mildew. The spore inhibition rate of YN201732M1 was only 30.29%, and the pot experiment control effect was less than 37.39%, which was significantly lower than that of the wild type. The inhibitory effect of mutant YN201732M2 (deficient in the production of bacillomycin D) and mutant YN201732M3 (deficient in the production of fengycin) on the spore germination of E. cichoracearum were 50.22% and 53.06%, respectively, suggesting that both fengycin and bacillomycin D had potential effects on spore germination of powdery mildew. Interestingly, in a greenhouse assay, both B. amyloliquefaciens YN201732M2 and YN201732M3 mutants displayed less of a control effect on tobacco powdery mildew than wild type. The results from in vitro, spore germination, and greenhouse-pot studies demonstrated that antimicrobial lipopeptides especially bacillomycin D and fengycin may contribute to the prevention and control of tobacco powdery mildew. In addition, gene mutation related to lipopeptide synthesis can also affect the biofilm formation of strains.
Paleo-Ecology of the Yedoma Ice Complex on Sobo-Sise Island (EasternLena Delta, Siberian Arctic)
Authors: Wetterich S. , Rudaya N. , Nazarova L. , Syrykh L. , Pavlova M. , Palagushkina O. , Kizyakov A. , Wolter J. , Kuznetsova T. , Aksenov A. , Stoof-Leichsenring K. R. , Schirrmeister L. , Fritz M. 
Published: June 2021

Late Pleistocene permafrost of the Yedoma type constitutes a valuable paleo-environmental archive due to the presence of numerous and well-preserved floral and faunal fossils. The study of the fossil Yedoma inventory allows for qualitative and quantitative reconstructions of past ecosystem and climate conditions and variations over time. Here, we present the results of combined paleo-proxy studies including pollen, chironomid, diatom and mammal fossil analyses from a prominent Yedoma cliff on Sobo-Sise Island in the eastern Lena Delta, NE Siberia to complement previous and ongoing paleo-ecological research in western Beringia. The Yedoma Ice Complex (IC) cliff on Sobo-Sise Island (up to 28 m high, 1.7 km long) was continuously sampled at 0.5 m resolution. The entire sequence covers the last about 52 cal kyr BP, but is not continuous as it shows substantial hiatuses at 36–29 cal kyr BP, at 20–17 cal kyr BP and at 15–7 cal kyr BP. The Marine Isotope Stage (MIS) 3 Yedoma IC (52–28 cal kyr BP) pollen spectra show typical features of tundra–steppe vegetation. Green algae remains indicate freshwater conditions. The chironomid assemblages vary considerably in abundance and diversity. Chironomid-based TJuly reconstructions during MIS 3 reveal warmer-than-today TJuly at about 51 cal kyr BP, 46-44 and 41 cal kyr BP. The MIS 2 Yedoma IC (28–15 cal kyr BP) pollen spectra represent tundra-steppe vegetation as during MIS 3, but higher abundance of Artemisia and lower abundances of algae remains indicate drier summer conditions. The chironomid records are poor. The MIS 1 (7–0 cal kyr BP) pollen spectra indicate shrub-tundra vegetation. The chironomid fauna is sparse and not diverse. The chironomid-based TJuly reconstruction supports similar-as-today temperatures at 6.4–4.4 cal kyr BP. Diatoms were recorded only after about 6.4 cal kyr BP. The Sobo-Sise Yedoma record preserves traces of the West Beringian tundra-steppe that maintained the Mammoth fauna including rare evidence for woolly rhinoceros’ presence. Chironomid-based TJuly reconstructions complement previous plant-macrofossil based TJuly of regional MIS 3 records. Our study from the eastern Lena Delta fits into and extends previous paleo-ecological Yedoma studies to characterize Beringian paleo-environments in the Laptev Sea coastal region.
Case Report: Sequential Chemotherapy and Immunotherapy Produce Sustained Response in Osteosarcoma With High Tumor Mutational Burden
Authors: Zheng Shuier , Wang Fenglin , Huang Jin , Zhou Yan , Yang Quanjun , Qian Guowei , Zhou Chenliang , Min Daliu , Song Lele , Shen Zan 
Published: June 2021

BackgroundImmunotherapy has provided an effective method for the treatment of many cancers. However, its efficacy in osteosarcoma is not satisfactory so far.Case PresentationHere, we presented a case of osteosarcoma treated with sequential chemotherapy and immunotherapy and showed promising therapeutic potential. The 29-year-old female patient presented 9th rib osteosarcoma with suspected right lung lower lobe metastasis. Surgery was performed to remove the primary lesion, and a series of chemotherapies were given afterward in consideration of the response and tolerance. The right lung lower lobe metastasis was under control first but progressed (PD) 9 months after the initiation of therapy. The lesion was surgically removed and subsequent chemotherapy was implemented. The patient had good tolerance with chemotherapy and maintained well for approximately 11 months before the discovery of 11th rib and right lung upper lobe metastases. Surgery was then performed on both lesions and achieved complete response. Post-surgical brief chemotherapy and subsequent long-term immunotherapy (pembrolizumab) maintained continuous remission for 33 months. The patient survived for 60 months with well-controlled disease from the time of confirmed diagnosis. Genetic alterations of all primary and metastatic lesions were investigated by whole-exome sequencing (WES). Substantial similarity in mutational landscape between the primary lesion and 11th rib metastasis and between the two lung metastases were revealed, while substantial heterogeneity was found between the rib lesions and lung metastases. The tumor mutational burden (TMB) for the 9th rib primary lesion, the metastatic 11th rib lesion, and the metastatic right upper and lower lobe nodule tissues was 8.02, 2.38, 4.61, and 0.14 mutations/Mb, respectively. The primary lesion exhibited the most diverse copy number variation (CNV) changes among all lesions. Furthermore, pathway enrichment analysis also suggested significant heterogeneity among the lesions.ConclusionsSurgery with sequential chemotherapy and maintenance immunotherapy was shown to have good response for the first time on osteosarcoma patient who had high TMB tumor lesions and good tolerance for chemotherapy and immunotherapy.