bluuebunny/crossref_metadata_2025_split huggingface dataset:
NONMMUT140591.1 may serve as a ceRNA to regulate Gata5 in UT-B knockout-induced cardiac conduction block
Authors: Lv Xuejiao , Sun Yuxin , Tan Wenxi , Liu Yang , Wen Naiyan , Fu Shuang , Yu Lanying , Liu Tiantian , Qi Xiaocui , Shu Nanqi , Du Yanwei , Zhang Wenfeng , Meng Yan 
Published: November 2021

Abstract
We intended to explore the potential molecular mechanisms underlying the cardiac conduction block inducted by urea transporter (UT)-B deletion at the transcriptome level. The heart tissues were harvested from UT-B null mice and age-matched wild-type mice for lncRNA sequencing analysis. Based on the sequencing data, the differentially expressed mRNAs (DEMs) and lncRNAs (DELs) between UT-B knockout and control groups were identified, followed by function analysis and mRNA–lncRNA co-expression analysis. The miRNAs were predicted, and then the competing endogenous RNA (ceRNA) network was constructed. UT-B deletion results in the aberrant expression of 588 lncRNAs and 194 mRNAs. These DEMs were significantly enriched in the inflammation-related pathway. A lncRNA–mRNA co-expression network and a ceRNA network were constructed on the basis of the DEMs and DELs. The complement 7 (C7)–NONMMUT137216.1 co-expression pair had the highest correlation coefficient in the co-expression network. NONMMUT140591.1 had the highest degree in the ceRNA network and was involved in the ceRNA of NONMMUT140591.1-mmu-miR-298-5p-Gata5 (GATA binding protein 5). UT-B deletion may promote cardiac conduction block via inflammatory process. The ceRNA NONMMUT140591.1-mmu-miR-298-5p-Gata5 may be a potential molecular mechanism of UT-B knockout-induced cardiac conduction block.
Molecular characterization and phylogenetic studies of Echinococcus granulosus and Taenia multiceps coenurus cysts in slaughtered sheep in Saudi Arabia
Authors: Al Malki Jamila S. , Hussien Nahed Ahmed 
Published: November 2021

Abstract
Taeniids, consisting of two genera Echinococcus and Taenia, are obligatory tapeworms of mammals, and their pathogenicity was due to infection with larval stages. Hydatid (the larval stage of Echinococcus granulosus) and coenurus (the larval stage of Taenia multiceps) cysts are prevalent in domestic, wild ruminants, livestock, swine, and dogs, and accidentally they could also be found in humans. They lead to different clinical manifestations that cause economic loss in livestock and human morbidity. In Saudi Arabia, few studies were performed on hydatid and coenurus cyst genetic variations. The main goal of the present study was to identify E. granulosus and T. multiceps cyst isolates collected from slaughtered Harri sheep in Saudi Arabia by partial sequencing with PCR amplification of the cytochrome C oxidase 1 (COX1) gene. Molecular and phylogenetic evaluation based on COX1 sequences indicated that cyst isolates belong to E. granulosus and T. multiceps, respectively, successfully submitted in NCBI Genbank. Molecular characterization showed a low nucleotide diversity with two submitted isolates of coenurus with related isolates of Genbank. Conversely, E. granulosus isolates showed higher nucleotide diversity. The reported data could serve as a foundation for future molecular epidemiological and biological studies.
Algebroids, AKSZ Constructions and Doubled Geometry
Authors: Marotta Vincenzo Emilio , Szabo Richard J. 
Published: November 2021

Abstract
We give a self-contained survey of some approaches aimed at a global description of the geometry underlying double field theory. After reviewing the geometry of Courant algebroids and their incarnations in the AKSZ construction, we develop the theory of metric algebroids including their graded geometry. We use metric algebroids to give a global description of doubled geometry, incorporating the section constraint, as well as an AKSZ-type construction of topological doubled sigma-models. When these notions are combined with ingredients of para-Hermitian geometry, we demonstrate how they reproduce kinematical features of double field theory from a global perspective, including solutions of the section constraint for Riemannian foliated doubled manifolds, as well as a natural notion of generalized T-duality for polarized doubled manifolds. We describe the L
∞-algebras of symmetries of a doubled geometry, and briefly discuss other proposals for global doubled geometry in the literature.
On the impact of clause order on pronoun resolution: evidence from Spanish
Authors: de Rocafiguera Núria , Bel Aurora 
Published: November 2021

Abstract
In research on intra-sentential pronominal anaphora resolution in null subject languages, it has been argued that null pronouns tend to be biased towards subject antecedents, whereas overt pronouns tend to prefer object antecedents, as predicted by Carminati’s ‘Position of the Antecedent Hypothesis’. However, these studies have mainly focused on only one of the two possible clause orders (main-subordinate or subordinate-main), which have not been overtly contrasted. This paper investigates the effects of clause order on the interpretation of third-person subject pronouns in globally ambiguous intra-sentential contexts by 49 native speakers of Spanish. The results of an acceptability judgment task explicitly comparing both clause orders indicate that relative clause order is a key factor affecting the interpretation of pronouns: while a preference of overt pronouns for object antecedents holds across clause orders, null pronouns show a bias towards subject antecedents only in subordinate-main sequences. These findings refine the Position of the Antecedent Hypothesis predictions by restricting them to subordinate-main complex sentences.
Reconfigurable bandstop filter using active frequency selective surface, design and fabrication
Authors: Babaei Hamed , Gohari Seyyed Amir 
Published: November 2021

Abstract
In this paper a novel FSS array is proposed, that provides dynamic band-gap in C-band. Inside the band-gap, the FSS acts as a bandstop filter. Outside the band-gap the amplitude of the reflected wave from the FSS array decreases. Therefore, the outside band is very useful in radar cross section (RCS) reduction. In this paper, at first a new FSS unit cell is designed, then in order to achieve the maximum bandwidth (1.2 GHz), dimensions of the cell are optimized. In the next step, the FSS cell is equipped with PIN diodes. Turning the diodes ON or OFF, shifts the resonant frequency of the band-gap electronically. When diodes are OFF, the resonant frequency and −10 dB bandwidth of the FSS are 5.23 and 0.9 GHz respectively. When the diodes turn ON, the resonant frequency shifts to 4.75 GHz over a bandwidth of about 1 GHz. While the band-gap is shifted dynamically, the bandwidth is kept wide, which is the novelty of this paper. In order to validate the design process, an array of active cells consisting of 128 pin diodes was designed, fabricated and then tested. Finally, the simulation and measurement results are compared with each other and a good agreement is observed between them.
Effect of Cu doping on the optical property of green synthesised l-cystein-capped CdSe quantum dots
Authors: Oluwafemi Oluwatobi Samuel , Parani Sundararajan , Lebepe Thabang Calvin , Maluleke Rodney 
Published: November 2021

Abstract
In the present study, the synthesis of water-soluble copper-doped CdSe nanoparticles (NPs) via a low cost, facile, and environmentally benign method is reported. Simple reagents such as selenium powder, cadmium chloride, and copper sulphate were used as selenium, cadmium, and copper precursor, respectively, while l-cysteine was used as a capping ligand without the use of an additional stabiliser. The as-synthesised copper-doped CdSe NPs were characterised using ultraviolet (UV-Vis) absorption and photoluminescence (PL) spectroscopy, Fourier-transform infrared spectroscopy, and transmission electron microscopy. By varying the dopant concentration, the temporal evolution of the optical properties and the shape of the nanocrystals were investigated. The observation and the results showed that the colour of the solution changed rapidly from orange to black, and the PL shifted to a longer wavelength at the high dopant concentration. The micrographic images revealed that the as-synthesised materials are small and could be used for bio labelling.
Utilization of shallot bio-waste (Allium cepa L. var. aggregatum) fractions for the production of functional cookies
Authors: Bhosale Yuvraj K. , Perumal Thivya , Varghese Shery M. , Vincent Hema , Ramachandran Sinija Vadakkepulppara 
Published: November 2021

Abstract
Shallot harvesting and processing produce various waste streams, and the current study aims to investigate the effects of shallot bio-waste powder (SWP) substitution on different flour properties. Increased SWP to 50% substitution of stalk and petiole showed a rise in swelling capacity (43.33%) and water absorption (342.22%), and oil absorption (320.73%), respectively. Foaming capacity improved from 48.00% in control to 60.26% in 30% flower substitution and further decreases to 51.28% at 50%. Pasting properties reduced at higher SWP substitution and the highest drop in peak viscosity was observed at Stalk-50 (457.33 cP). Subsequently, developed functional cookies showed enhanced fiber, ash, total phenol, and total flavonoids with 3, 2, 7, and 5 fold, respectively. Cookies developed with higher substitution were of darker color and higher hardness and fracturability. Sensory evaluation with fuzzy analysis revealed better acceptance for stalk and petiole (10%) and peel (5%) of final cookies with elevated nutritional value.
Morphological, structural and physicochemical properties of rice starch nanoparticles prepared via ultra-high pressure homogenization
Authors: Sun Chengyi , Hu Yuqing , Yu Xietian , Zhu Zhijie , Hao Shuai , Du Xianfeng 
Published: November 2021

Abstract
Native rice starches were treated with five periods of ultra-high pressure homogenization (UHPH) under each of 60, 80, 100, 120, 140 and 160 MPa, respectively. The morphological, structural and physicochemical properties of starches treated with UHPH were examined. The mean particle diameter of starch nanoparticles ranged between 154.20 and 260.40 nm. SEM revealed that the granular amorphous region of starch granules was damaged under pressures between 60 and 80 MPa, and the crystalline region was further destroyed under pressures as high as 100–160 MPa. DSC demonstrated that the gelatinization temperatures and enthalpies of nanoparticles reduced. The relative crystallinity reduced from 22.90 to 13.61% as the pressure increased. FTIR showed that the absorbance ratio at 1047/1022 cm−1 decreased, and increased at 1022/995 cm−1. RVA results indicated that the viscosity of starch samples increased between 60 and 120 MPa, and the reverse effect was observed under 140 and 160 MPa.
Ich! – Wer ich? Zur Interaktion im Online-Unterricht
Authors: Rösler Dietmar , Zeyer Tamara 
Published: November 2021

Zusammenfassung
In diesem Beitrag werden Aufzeichnungen von Unterricht analysiert, der pandemiebedingt kurzfristig digitalisiert werden musste. Die Daten stammen aus dem Deutschunterricht für studieninteressierte Geflüchtete auf dem Sprachniveau B1+, der mithilfe des Webkonferenztools Cisco Webex stattfand. Die Auswertung der Daten konzentriert sich auf die unterschiedlichen Ansichten des Unterrichts auf den Bildschirmen der Beteiligten und die daraus folgenden didaktischen Konsequenzen, auf den Übergang von Stillarbeit zum gemeinsamen Arbeiten und auf den Umgang der Lehrkräfte mit Nachfragen der Lernenden und Fehlern. Gezeigt wird außerdem durch die Analyse einer längeren Sequenz, wie der Übergang von der Arbeit an einer formfokussierten Übung zur freien Diskussion über für die Lernenden relevante Themen verläuft.
Towards a typology of middle voice systems
Authors: Inglese Guglielmo 
Published: November 2021

AbstractThe middle voice is a notoriously controversial typological notion. Building on previous work (e.g. Kemmer, Suzanne. 1993.The middle voice. Amsterdam & Philadelphia: John Benjamins), in this paper I propose a new working definition of middle markers as inherently polyfunctional constructions which are partly associated with valency change in opposition to bivalent (or more) verbs and partly lexically obligatory with monovalent verbs. Based on this definition, the paper undertakes a systematic survey of 149 middle voice constructions in a sample of 129 middle-marking languages. Evidence from the sample shows that middle voice systems display a much richer variation in forms and functions than is reported in the literature. This richer empirical evidence challenges some of the mainstream views on middle marking, especially its purported connection with reflexivity and grooming-type events, and calls for an overall rethinking of the typology of the middle voice.
Sub-Saharan African Countries‘ COVID-19 Research: An analysis of the External and Internal Contributions, Collaboration Patterns and Funding Sources
Authors: Asubiaro Toluwase Victor , Shaik Hafsah 
Published: November 2021

AbstractThis study aims at providing some evidence-based insight into Sub-Saharan Africa’s first eighteen months of COVID-19 research by evaluating its research contributions, patterns of collaboration, and funding sources. Eighteen months (2020 January 1-2021 June 30) COVID-19 publication data of 46 Sub-Saharan African countries was collected from Scopus for analysis. Country of affiliation of the authors and funding agencies data was analyzed to understand country contributions, collaboration pattern and funding sources. USA (23.08%) and the UK (19.63%), the top two external contributors, collaborated with Sub-Saharan African countries about three times more than other countries. Collaborative papers between Sub-Saharan African countries - without contributions from outside the region- made up less than five per cent of the sample, whereas over 50% of the papers were written in collaboration with researchers from outside the region. Organizations that are in the USA and the UK funded 45% of all the COVID-19 research from Sub-Saharan Africa. 53.44% of all the funding from Sub-Saharan African countries came from South African organizations. This study provides evidence that pan-African COVID-19 research collaboration is low, perhaps due to poor funding and lack of institutional support within Sub-Saharan Africa. This mirrors the collaborative features of science in Sub-Saharan Africa before the COVID-19 pandemic. The high volume of international collaboration during the pandemic is a good development. There is also a strong need to forge more robust pan-African research collaboration networks, through funding from Africa’s national and regional government organizations, with the specific objective of meeting local COVID-19 and other healthcare needs.
Ramie fiber reinforced composites with flame retardant structure design: flammability, smoke suppression, and mechanical properties
Authors: Zhu Chenkai , Nie Lei , Yan Xiaofei , Li Jiawei , Qi Dongming 
Published: November 2021

Abstract
In this work, the structure of composite was designed as Core Stack and Surface Stack, which was treated with the expandable graphite (EG) and metal oxides such as iron oxide (IO), hydroxyapatite (HA), and aluminum tri-hydroxide (ATH). The mechanical performance of composites was characterized via flexural performance and interlaminar shear strength analysis. The flame retardance and smoke suppression of composite was explored in detail by LOI, UL-94, and cone calorimeter test. The findings presented that flexural properties of composites were observed to decrease due to delamination of surface stack, whilst no significant effect on interlaminar shear strength. In comparison with control composite, the loading of metal oxide into composite Surface Stack led to the reduction of peak heat release rate, total heat release, and fire growth index effectively. Moreover, the remarkable decrease in total smoke production could be observed due to the addition of iron oxide and the flame retardant mechanism was discussed. This study was the preliminary exploration of composite with flame retardant design which could be potential solution to improve flame retardancy and smoke suppression of composite with better mechanical structure preservation.
Global load determination in linear guides based on the fusion of local rolling element loads determined from strain sensitive sensor groups
Authors: Krampert David , Unsleber Sebastian , Reindl Leonhard , Rupitsch Stefan J. 
Published: November 2021

Abstract
Measuring the mechanical load on linear guides provides many possibilities regarding predictive maintenance and process monitoring. In this contribution, we provide an in depth evaluation of a Diamond Like Carbon (DLC) based sensor system integrated into the runner block’s raceway that is capable of directly measuring the load on individual rolling elements. An efficient algorithm based on an Extended Kalman Filter (EKF) for local sensor fusion and load estimation is presented and proven to reliably retrieve the load regardless of the rolling element’s position. Afterwards, we compare locally measured loads to results from a theoretical load distribution model, providing valuable insight into modeling parameters and a verification of the sensor measurement principle. In a final step, an algorithm to invert the load distribution model is derived and used for an evaluation of the sensor system, achieving Root-Mean-Square (RMS) estimation errors of equivalently 1.4 kN in the preload range and 2.75 kN overall for one dimensional loads. Load mode distinction was equally successful with a suppression RMS error of 0.7 kN in the preload range and 2.87 kN in total.
Back to the roots: the concepts of force and energy
Authors: Kalies Grit 
Published: November 2021

Abstract
The concepts of force and energy are analyzed in the context of state and process equations. In chronological order, the application of the cause-effect principle in process equations is studied in mechanics, thermodynamics, special relativity, general relativity, and quantum theory. The differences in the fundamental approaches to nature and the significance of a consistent physical interpretation of formulas and state variables are emphasized. It is shown that the first origins for the crisis of modern theoretical physics are to be found in the concepts of force and energy in mechanics, which partly violate the cause-effect principle. This affects all theories based on mechanics and underlines their historical conditionality. The systematic application of driving forces and the cause-effect principle in process equations suggests a return to causal realistic physics. It meets the wave character of matter, is compatible with the experiment, and allows a unified description of interaction.
Characterizing the Tapering Practices of United States and Canadian Raw Powerlifters
Authors: Travis S. Kyle , Pritchard Hayden J. , Mujika Iñigo , Gentles Jeremy A. , Stone Michael H. , Bazyler Caleb D. 
Published: November 2021

Abstract
Travis, SK, Pritchard, HJ, Mujika, I, Gentles, JA, Stone, MH, and Bazyler, CD. Characterizing the tapering practices of United States and Canadian raw powerlifters. J Strength Cond Res 35(12S): S26–S35, 2021—The purpose of this study was to characterize the tapering practices used by North American powerlifters. A total of 364 powerlifters completed a 41-item survey encompassing demographics, general training, general tapering, and specific tapering practices. Nonparametric statistics were used to assess sex (male and female), competition level (regional/provincial, national, and international), and competition lift (squat, bench press, and deadlift). The highest training volume most frequently took place 5–8 weeks before competition, whereas the highest training intensity was completed 2 weeks before competition. A step taper was primarily used over 7–10 days while decreasing the training volume by 41–50% with varied intensity. The final heavy (>85% 1 repetition maximum [1RM]) back squat and deadlift sessions were completed 7–10 days before competition, whereas the final heavy bench press session was completed <7 days before competition. Final heavy lifts were completed at 90.0–92.5% 1RM but reduced to 75–80% 1RM for back squat and bench press and 70–75% for deadlift during the final training session of each lift. Set and repetition schemes during the taper varied between lifts with most frequent reports of 3 × 2, 3 × 3, and 3 × 1 for back squat, bench press, and deadlift, respectively. Training cessation durations before competition varied between deadlift (5.8 ± 2.5 days), back squat (4.1 ± 1.9 days), and bench press (3.9 ± 1.8 days). Complete training cessation was implemented 2.8 ± 1.1 days before competition and varied between sex and competition level. These findings provide novel insights into the tapering practices of North American powerlifters and can be used to inform powerlifting coaches and athlete's tapering decisions.
Sparser and Less Efficient Hippocampal-Prefrontal Projections account for Developmental Network Dysfunction in a Model of Psychiatric Risk Mediated by Gene-Environment Interaction
Authors: Song Lingzhen , Xu Xiaxia , Putthoff Peggy , Fleck David , Spehr Marc , Hanganu-Opatz Ileana L. 
Published: November 2021

Precise information flow from the hippocampus (HP) to prefrontal cortex (PFC) emerges during early development and accounts for cognitive processing throughout life. On flip side, this flow is selectively impaired in mental illness. In mouse models of psychiatric risk mediated by gene-environment interaction (GE), the prefrontal-hippocampal coupling is disrupted already shortly after birth. While this impairment relates to local miswiring in PFC and HP, it might be also because of abnormal connectivity between the two brain areas. Here, we test this hypothesis by combiningin vivoelectrophysiology and optogenetics with in-depth tracing of projections and monitor the morphology and function of hippocampal afferents in the PFC of control and GE mice of either sex throughout development. We show that projections from the hippocampal CA1 area preferentially target layer 5/6 pyramidal neurons and interneurons, and to a lesser extent layer 2/3 neurons of prelimbic cortex (PL), a subdivision of PFC. In neonatal GE mice, sparser axonal projections from CA1 pyramidal neurons with decreased release probability reach the PL. Their ability to entrain layer 5/6 oscillatory activity and firing is decreased. These structural and functional deficits of hippocampal-prelimbic connectivity persist, yet are less prominent in prejuvenile GE mice. Thus, besides local dysfunction of HP and PL, weaker connectivity between the two brain areas is present in GE mice throughout development.SIGNIFICANCE STATEMENTPoor cognitive performance in mental disorders comes along with prefrontal-hippocampal dysfunction. Recent data from mice that model the psychiatric risk mediated by gene-environment (GE) interaction identified the origin of deficits during early development, when the local circuits in both areas are compromised. Here, we show that sparser and less efficient connectivity as well as cellular dysfunction are the substrate of the weaker excitatory drive from hippocampus (HP) to prefrontal cortex (PFC) as well as of poorer oscillatory coupling between the two brain areas in these mice. While the structural and functional connectivity deficits persist during the entire development, their magnitude decreases with age. The results add experimental evidence for the developmental miswiring hypothesis of psychiatric disorders.