bluuebunny/crossref_metadata_2025_split huggingface dataset:
Resolving the spatial distributions of Dipturus intermedius and Dipturus batis—the two taxa formerly known as the ‘common skate’
Authors: Bache-Jeffreys Maisie , de Moraes Bárbara Lins Caldas , Ball Rachel E. , Menezes Gui , Pálsson Jónbjörn , Pampoulie Christophe , Stevens Jamie R. , Griffiths Andrew M. 
Published: July 2021

AbstractBatoid fishes are among the most endangered marine vertebrates, yet conservation efforts have been confounded by incomplete taxonomy. Evidence suggest that the critically endangered ‘common skate’ actually represents two species: the flapper skate (Dipturus intermedius) and the blue skate (Dipturus batis). However, knowledge of the geographic range of these two nominal species is limited. Here, DNA sequencing is used to distinguish these species, allowing their spatial distributions to be clarified. These records were also used as the basis for species distribution modelling, providing the first broad scale models for each species across the Northeast Atlantic. Samples were obtained from Iceland, the UK (specifically Shetland), the North Sea and the Azores. Results suggest that D. batis was commonly distributed in the Western Approaches and Celtic Sea, extending out to Rockall and Iceland. D. intermedius generally appears to be less abundant, but was most frequent around northern Scotland and Ireland, including the northern North Sea, and was also present in Portugal. Two individuals were also identified from seamounts in remote areas of the Atlantic around the Azores, the furthest south and west the species has been found. This supports reports that the flapper skate historically had a much wider distribution (which was also highlighted in the distribution model), emphasising the large scale over which fisheries may have led to extirpations. Furthermore, these Azorean samples shared a unique control region haplotype, highlighting the importance of seamounts in preserving genetic diversity.
Space Project for Astrophysical and Cosmological Exploration (SPACE), an ESA stand-alone mission and a possible contribution to the Origins Space Telescope
Authors: Burgarella Denis , Bunker Andrew , Bouwens Rychard , Pagani Laurent , Afonso Jose , Atek Hakim , Audard Marc , Cabrit Sylvie , Caputi Karina , Ciesla Laure , Conselice Christopher , Cooray Asantha , Cresci Giovanni , Curti Mirko , Espinosa José Miguel Rodríguez , Ferrari Marc , Kobayashi Chiaki , Lagarde Nadège , Maestro Jesus Gallego , Maiolino Roberto , Malek Katarzyna , Mannucci Filippo , Montillaud Julien , Oesch Pascal , Pearson Chris , Pollo Agnieszka , Reylé Céline , Rosario David , Sakon Itsuki , Schaerer Daniel , Sharples Ray , Sobral David , Zamkotsian Frédéric 
Published: July 2021

AbstractWe propose a new mission called Space Project for Astrophysical and Cosmological Exploration (SPACE) as part of the ESA long term planning Voyage 2050 programme.SPACEwill study galaxy evolution at the earliest times, with the key goals of charting the formation of the heavy elements, measuring the evolution of the galaxy luminosity function, tracing the build-up of stellar mass in galaxies over cosmic time, and finding the first super-massive black holes (SMBHs) to form. The mission will exploit a unique region of the parameter space, between the narrow ultra-deep surveys with HST and JWST, and shallow wide-field surveys such as the Roman Space Telescope and EUCLID, and should yield by far the largest sample of any current or planned mission of very high redshift galaxies at z > 10 which are sufficiently bright for detailed follow-up spectroscopy. Crucially, we propose a wide-field spectroscopic near-IR + mid-IR capability which will greatly enhance our understanding of the first galaxies by detecting and identifying a statistical sample of the first galaxies and the first supermassive black holes, and to chart the metal enrichment history of galaxies in the early Universe – potentially finding signatures of the very first stars to form from metal-free primordial gas. The wide-field and wavelength range ofSPACEwill also provide us a unique opportunity to study star formation by performing a wide survey of the Milky Way in the near-IR + mid-IR. This science project can be enabled either by a stand-alone ESA-led M mission or by an instrument for an L mission (with ESA and/or NASA, JAXA and other international space agencies) with a wide-field (sub-)millimetre capability at λ > 500 μm.
Inference of time series components by online co-evolution
Authors: Koryakin Danil , Otte Sebastian , Butz Martin V. 
Published: July 2021

AbstractTime series data is often composed of a multitude of individual, superimposed dynamics. We propose a novel algorithm for inferring time series compositions through evolutionary synchronization of modular networks (ESMoN). ESMoN orchestrates a set of trained dynamic modules, assuming that some of those modules’ dynamics, suitably parameterized, will be present in the targeted time series. With the help of iterative co-evolution techniques, ESMoN optimizes the activities of its modules dynamically, which effectively synchronizes the system with the unfolding time series signal and distributes the dynamic subcomponents present in the time series over the respective modules. We show that ESMoN can adapt modules of different types. Moreover, it is able to precisely identify the signal components of various time series dynamics. We thus expect that ESMoN will be useful also in other domains—including, for example, medical, physical, and behavioral data domains—where the data is composed of known signal sources.
RETRACTED ARTICLE: Autism Tsunami: the Impact of Rising Prevalence on the Societal Cost of Autism in the United States
Authors: Blaxill Mark , Rogers Toby , Nevison Cynthia 
Published: July 2021

AbstractThe cost of ASD in the U.S. is estimated using a forecast model that for the first time accounts for the true historical increase in ASD. Model inputs include ASD prevalence, census population projections, six cost categories, ten age brackets, inflation projections, and three future prevalence scenarios. Future ASD costs increase dramatically: total base-case costs of $223 (175–271) billion/year are estimated in 2020; $589 billion/year in 2030, $1.36 trillion/year in 2040, and $5.54 (4.29–6.78) trillion/year by 2060, with substantial potential savings through ASD prevention. Rising prevalence, the shift from child to adult-dominated costs, the transfer of costs from parents onto government, and the soaring total costs raise pressing policy questions and demand an urgent focus on prevention strategies.
Holocene paleoenvironmental change inferred from two sediment cores collected in the Tibetan lake Taro Co
Authors: Laug Andreas , Haberzettl Torsten , Pannes Andre , Schwarz Anja , Turner Falko , Wang Junbo , Engels Stefan , Rigterink Sonja , Börner Nicole , Ahlborn Marieke , Ju Jianting , Schwalb Antje 
Published: July 2021

AbstractThe Tibetan Plateau, also known as the “Water Tower of Asia” because of its function as a water storage and supply region, responds dramatically to modern climate changes. Paleoecological shifts inferred from lake sediment archives provide essential insights into past climate changes, and the processes that drove those shifts. This is especially true for studies of lakes in endorheic basins on the Tibetan Plateau, where lake level is regulated predominantly by Monsoon intensity. Such water bodies provide excellent opportunities to reconstruct past changes in humidity. Most paleolimnological investigations of lakes on the Tibetan Plateau, however, have involved the study of a single sediment core, making it difficult to discern between changes caused by local events and those caused by lake-wide or regional processes. Here we present results from a paleolimnological study of Lake Taro Co, a currently closed-basin lake in Central Tibet. We compared a sediment record from the central part of the lake to a record from the near-shore area, and present results of sedimentological and bioindicator (chironomid, diatom, pollen) analyses from both records. Results show three periods of lake-wide ecosystem change (> ca. 5250, 5250–2250 and < since about 2250 cal year BP), which reflect a continuous drying trend throughout the Middle and Late Holocene. In addition to this lake-wide trend, we identified two local events in the sediment core from the southeastern, nearshore site. These include (1) a hiatus between 12,400 and 5400 cal year BP and (2) an 1800-year period of distinct paleoenvironmental conditions (5400–3600 cal year BP). We hypothesize that both events were caused by relocation of a river in the southeast sector of the lake’s catchment. We propose that the first relocation caused an erosion event that removed sediment, thereby producing the hiatus. During the following 1800 years, the core site may have been located on the river delta, before another river relocation at 3600 cal year BP established the modern prodelta situation. Our study demonstrates the value of using multiple sediment cores from a lake, to better identify processes that control widespread versus local events.
Robust fuzzy delayed sampled-data control for nonlinear active suspension systems with varying vehicle load and frequency-domain constraint
Authors: Hu Meng-Jie , Park Ju H. , Cheng Jun 
Published: July 2021

AbstractThis article studies the Takagi-Sugeno (T-S) fuzzy delayed sampled-data $$\mathcal {H}_\infty $$

H
∞

control problem for a class of intelligent suspension systems with varying vehicle load and frequency-domain constraint. The T-S fuzzy model is utilized to characterize the varying vehicle load. Considering the transmission delay, a robust fuzzy delayed sampled-data control mechanism is newly propounded for suspension systems. According to the Lyapunov stability theory, a useful theorem is proposed based on the Wirtinger inequality to guarantee the states of the active suspension system being asymptotically stabilized with the required $$\mathcal {H}_\infty $$

H
∞

performance by the proposed controller. Moreover, the suspension constrained requirements are also satisfied within the finite frequency domain. Finally, simulation examples are presented to attest to the usefulness and superiority of the proposed controller.
Neurodevelopmental disorders in youth justice: a systematic review of screening, assessment and interventions
Authors: Holland Lorelle , Reid Natasha , Smirnov Andrew 
Published: July 2021

Abstract
Objectives
This study aims to systematically review screening and assessment approaches and therapeutic interventions for young people with neurodevelopmental disorders (NDDs) in the youth justice system (YJS).

Method
Five databases were searched (PubMed, Embase, CINAHL, Web of Science and PsycINFO) for studies evaluating effectiveness of screening, assessment or interventions, targeting people aged 10–18 years in youth justice with a NDD.

Results
Eighteen peer-reviewed articles (9 screening/assessment; 9 intervention studies) were eligible. More comprehensive assessment appeared to be superior to brief screening for identifying NDDs. Interventions addressed social and emotional wellbeing, educational, employment, language and communication and behavioural outcomes, community engagement, quality of life factors and recidivism. Limited consideration was given to cultural diversity in evaluations of screening, assessment or interventions.

Conclusions
The limited amount of evidence retrieved suggests further research is urgently needed in the provision of culturally competent and holistic screening, assessment and treatment for young people with NDDs in the YJS.
Risk Imposition and Liability to Defensive Harm
Authors: Frowe Helen 
Published: July 2021

AbstractAccording to Jonathan Quong’s moral status account of liability to defensive harm, an agent is liable to defensive harm only when she mistakenly treats others as if their moral status is diminished (for example, as if they lack a right that they in fact possess). Quong argues that, by the lights of the moral status account, a conscientious driver (Driver) who faultlessly threatens to kill Pedestrian is not liable to defensive harm. Quong argues that Driver’s action is evidence-relative permissible, despite the risks it imposes, because the general practice of prudent driving is permissible. The practice is permissible because (a) its risks do not disproportionately fall on some groups rather than others, (b) the threatened harms are incidental, and (c) the risk that driving imposes is acceptable in light of the benefits everyone derives from driving. Because the correct moral theory tells us that prudent driving is permissible, Pedestrian lacks a right that Driver refrain from driving. Hence, Driver does not, by driving, treat Pedestrian as lacking a right that Pedestrian in fact possesses. Driver is not liable to defensive force. I argue, against Quong, that cost–benefit analyses of types of risky activity cannot justify individual tokens of risk imposition. Actions that risk incidentally harming others must be justified by the prospective benefits of that token action. Hence, Driver’s imposition of risk on Pedestrian cannot be justified by the benefits of the general practice of driving. I argue that the permissibility of Driver’s imposing risk on Pedestrian via prudent driving turns on whether Driver is willing to internalise at least the foreseeable costs of that risky action. One can lack a right that a person refrain from performing a risky action whilst possessing a right not to be harmed by that risky action. Even if Pedestrian cannot reasonably demand that Driver refrain from driving, she can reasonably demand that Driver refrain from forcing her to bear the costs of his driving.
Intimate atomic Cu-Ag interfaces for high CO2RR selectivity towards CH4 at low over potential
Authors: Choi Chungseok , Cai Jin , Lee Changsoo , Lee Hyuck Mo , Xu Mingjie , Huang Yu 
Published: July 2021

AbstractDeveloping highly efficient electrochemical catalysts for carbon dioxide reduction reaction (CO2RR) provides a solution to battle global warming issues resulting from ever-increasing carbon footprint due to human activities. Copper (Cu) is known for its efficiency in CO2RR towards value-added hydrocarbons; hence its unique structural properties along with various Cu alloys have been extensively explored in the past decade. Here, we demonstrate a two-step approach to achieve intimate atomic Cu-Ag interfaces on the surface of Cu nanowires, which show greatly improved CO2RR selectivity towards methane (CH4). The specially designed Cu-Ag interfaces showed an impressive maximum Faradaic efficiency (FE) of 72% towards CH4production at −1.17 V (vs. reversible hydrogen electrode (RHE)).
The effect of support on RhFe/Al2O3 for ethanol synthesis via CO hydrogenation
Authors: Li Fang , Qian Weixing 
Published: July 2021

AbstractDifferent alumina samples prepared with sol–gel, chemical precipitation and hydrothermal synthesis were used as supports of Fe-promoted Rh-based catalysts for ethanol synthesis via CO hydrogenation. The samples were characterized by means of N2-adsorpotion, XRD, H2-TPR, XPS, STEM, H2-TPD, DRIFTS, H2 and CO chemisorption. The results indicated that the Al2O3 prepared by hydrothermal synthesis exhibited nano-fiber morphology and constituted of mixed crystal phases, while Al2O3 prepared by sol–gel and chemical precipitation shows no changes of morphology and crystal phases compared with the commercial Al2O3. In addition, nano-fiber Al2O3-supported Rh-based catalyst shows higher ethanol selectivity, which is ascribed to the lower metal–support interaction, higher dispersion and stronger CO insertion ability.
Progress and challenges towards additive manufacturing of SiC ceramic
Authors: He Rujie , Zhou Niping , Zhang Keqiang , Zhang Xueqin , Zhang Lu , Wang Wenqing , Fang Daining 
Published: July 2021

AbstractSilicon carbide (SiC) ceramic and related materials are widely used in various military and engineering fields. The emergence of additive manufacturing (AM) technologies provides a new approach for the fabrication of SiC ceramic products. This article systematically reviews the additive manufacturing technologies of SiC ceramic developed in recent years, including Indirect Additive Manufacturing (Indirect AM) and Direct Additive Manufacturing (Direct AM) technologies. This review also summarizes the key scientific and technological challenges for the additive manufacturing of SiC ceramic, and also forecasts its possible future opportunities. This paper aims to provide a helpful guidance for the additive manufacturing of SiC ceramic and other structural ceramics.
Generalized Dobrushin Coefficients on Banach Spaces
Authors: Bartoszek Wojciech , Beśka Marek , Florek Wiktor 
Published: July 2021

AbstractThe asymptotic behavior of iterates of bounded linear operators (not necessarily positive), acting on Banach spaces, is studied. Through the Dobrushin ergodicity coefficient, we generalize some ergodic theorems obtained earlier for classical Markov semigroups acting on$$L^1$$L1(or positive operators on abstract state spaces).
CoBRA: Containerized Bioinformatics Workflow for Reproducible ChIP/ATAC-Seq Analysis
Authors: Qiu Xintao , Feit Avery S. , Feiglin Ariel , Xie Yingtian , Kesten Nikolas , Taing Len , Perkins Joseph , Gu Shengqing , Li Yihao , Cejas Paloma , Zhou Ningxuan , Jeselsohn Rinath , Brown Myles , Shirley Liu X. , Long Henry W. 
Published: July 2021

Abstract
Chromatin immunoprecipitation sequencing (ChIP-seq) and the Assay for Transposase-Accessible Chromatin with high-throughput sequencing (ATAC-seq) have become essential technologies to effectively measure protein–DNA interactions and chromatin accessibility. However, there is a need for a scalable and reproducible pipeline that incorporates proper normalization between samples, correction of copy number variations, and integration of new downstream analysis tools. Here we present Containerized Bioinformatics workflow for Reproducible ChIP/ATAC-seq Analysis (CoBRA), a modularized computational workflow which quantifies ChIP-seq and ATAC-seq peak regions and performs unsupervised and supervised analyses. CoBRA provides a comprehensive state-of-the-art ChIP-seq and ATAC-seq analysis pipeline that can be used by scientists with limited computational experience. This enables researchers to gain rapid insight into protein–DNA interactions and chromatin accessibility through sample clustering, differential peak calling, motif enrichment, comparison of sites to a reference database, and pathway analysis. CoBRA is publicly available online at https://bitbucket.org/cfce/cobra
Single-Cell Long Non-Coding RNA Landscape of T Cells in Human Cancer Immunity
Authors: Luo Haitao , Bu Dechao , Shao Lijuan , Li Yang , Sun Liang , Wang Ce , Wang Jing , Yang Wei , Yang Xiaofei , Dong Jun , Zhao Yi , Li Furong 
Published: July 2021

Abstract
The development of new biomarkers or therapeutic targets for cancer immunotherapies requires deep understanding of T cells. To date, the complete landscape and systematic characterization of long noncoding RNAs (lncRNAs) in T cells in cancer immunity are lacking. Here, by systematically analyzing full-length single-cell RNA sequencing (scRNA-seq) data of more than 20,000 libraries of T cells across three cancer types, we provided the first comprehensive catalog and the functional repertoires of lncRNAs in human T cells. Specifically, we developed a custom pipeline for de novotranscriptome assembly and obtained a novel lncRNA catalog containing 9433 genes. This increased the number of current human lncRNA catalog by 16% and nearly doubled the number of lncRNAs expressed in T cells. We found that a portion of expressed genes in single T cells were lncRNAs which had been overlooked by the majority of previous studies. Based on metacell maps constructed by the MetaCell algorithm that partitions scRNA-seq datasets into disjointed and homogenous groups of cells (metacells), 154 signature lncRNA genes were identified. They were associated with effector, exhausted, and regulatory T cell states. Moreover, 84 of them were functionally annotated based on the co-expression networks, indicating that lncRNAs might broadly participate in the regulation of T cell functions. Our findings provide a new point of view and resource for investigating the mechanisms of T cell regulation in cancer immunity as well as for novel cancer-immune biomarker development and cancer immunotherapies
Comparative Secretome Analysis of Magnaporthe oryzae Identified Proteins Involved in Virulence and Cell Wall Integrity
Authors: Liu Ning , Qi Linlu , Huang Manna , Chen Deng , Yin Changfa , Zhang Yiying , Wang Xingbin , Yuan Guixin , Wang Rui-Jin , Yang Jun , Peng You-Liang , Lu Xunli 
Published: July 2021

Abstract
Plant fungal pathogens secrete numerous proteins into the apoplast at the plant–fungus contact sites to facilitate colonization. However, only a few secretory proteins were functionally characterized in Magnaporthe oryzae, the fungal pathogen causing rice blast disease worldwide. Asparagine-linked glycosylation 3 (Alg3) is an α-1,3-mannosyltransferase functioning in the N-glycan synthesis of N-glycosylated secretory proteins. Fungal pathogenicity and cell wall integrity are impaired in Δalg3 mutants, but the secreted proteins affected in Δalg3 mutants are largely unknown. In this study, we compared the secretome s of the wild-type strain and the Δalg3 mutant and identified 51 proteins that require Alg3 for proper secretion. These proteins were predicted to be involved in metabolic processes, interspecies interactions, cell wall organization, and response to chemicals. Nine proteins were selected for further validation. We found that these proteins were localized at the apoplastic region surrounding the fungal infection hyphae. Moreover, the N-glycosylation of these proteins was significantly changed in the Δalg3 mutant, leading to the decreased protein secretion and abnormal protein localization. Furthermore, we tested the biological functions of two genes, INV1 (encoding invertase 1, a secreted invertase) and AMCase (encoding acid mammalian chinitase, a secreted chitinase). The fungal virulence was significantly reduced, and the cell wall integrity was altered in the Δinv1 and Δamcase mutant strains. Moreover, the N-glycosylation was essential for the function and secretion of AMCase. Taken together, our study provides new insight into the role of N-glycosylated secretory proteins in fungal virulence and cell wall integrity.