bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regional difference of sea surface salinity variations in the western tropical pacific
Authors: Ouyang Yating , Zhang Yuhong , Chi Jianwei , Sun Qiwei , Du Yan 
Published: February 2021

AbstractRegional difference of sea surface salinity (SSS) variations in the western tropical Pacific is investigated with Ocean Reanalysis System 5 datasets. Three robust zonal bands of SSS variations have been identified in the northwestern tropical Pacific (NWTP), the western equatorial tropical Pacific (WEqP), and the southwestern tropical Pacific (SWTP), respectively. SSS in the WEqP and the SWTP has a strong interannual variability that is related to ENSO. In the WEqP, SSS variations are mainly controlled by anomalous freshwater flux, while in the SWTP they are governed by both freshwater forcing and oceanic processes. In the NWTP, SSS variations present a low-frequency variability that is correlated with Interdecadal Pacific Oscillation (IPO), which is mostly dominated by the freshwater flux and strongly adjusted by the ocean advection and mixed layer changes. After removing interannual signals, the SSS in all three regions are highly related to IPO, indicating that IPO has a general influence on the western tropical Pacific.
Visualizing correlations among Parkinson biomedical data through information retrieval and machine learning techniques
Authors: Frasca Maria , Tortora Genoveffa 
Published: February 2021

AbstractIn the last few years, the integration of researches in Computer Science and medical fields has made available to the scientific community an enormous amount of data, stored in databases. In this paper, we analyze the data available in the Parkinson’s Progression Markers Initiative (PPMI), a comprehensive observational, multi-center study designed to identify progression biomarkers important for better treatments for Parkinson’s disease. The data of PPMI participants are collected through a comprehensive battery of tests and assessments including Magnetic Resonance Imaging and DATscan imaging, collection of blood, cerebral spinal fluid, and urine samples, as well as cognitive and motor evaluations. To this aim, we propose a technique to identify a correlation between the biomedical data in the PPMI dataset for verifying the consistency of medical reports formulated during the visits and allow to correctly categorize the various patients. To correlate the information of each patient’s medical report, Information Retrieval and Machine Learning techniques have been adopted, including the Latent Semantic Analysis, Text2Vec and Doc2Vec techniques. Then, patients are grouped and classified into affected or not by using clustering algorithms according to the similarity of medical reports. Finally, we have adopted a visualization system based on the D3 framework to visualize correlations among medical reports with an interactive chart, and to support the doctor in analyzing the chronological sequence of visits in order to diagnose Parkinson’s disease early.
A multidimensional phenomenal space for pain: structure, primitiveness, and utility
Authors: Coninx Sabrina 
Published: February 2021

AbstractPain is often used as the paradigmatic example of a phenomenal kind with a phenomenal quality common and unique to its instantiations. Philosophers have intensely discussed the relation between the subjective feeling, which unites pains and distinguishes them from other experiences, and the phenomenal properties of sensory, affective, and evaluative character along which pains typically vary. At the center of this discussion is the question whether the phenomenal properties prove necessary and/or sufficient for pain. In the empirical literature, sensory, affective, and evaluative properties have played a decisive role in the investigation of psychophysical correspondence and clinical diagnostics. This paper addresses the outlined philosophical and empirical issues from a new perspective by constructing amultidimensional phenomenal spacefor pain. First, the paper will construe the phenomenal properties of pains in terms of a property space whosestructurereflects phenomenal similarities and dissimilarities by means of spatial distance. Second, philosophical debates on necessary and sufficient properties are reconsidered in terms of whether there is a phenomenal space formed of dimensions along which all and only pains vary. It is concluded that there is no space of this kind and, thus, that pain constitutes aprimitivephenomenal kind that cannot be analyzed entirely in terms of its varying phenomenal properties. Third, the paper addresses theutilityof continued reference to pain and its phenomenal properties in philosophical and scientific discourses. It is argued that numerous insights into the phenomenal structure of pain can be gained that have thus far received insufficient attention.
UltraSynth: Insights of a CGRA Integration into a Control Engineering Environment
Authors: Wolf Dennis , Engel Andreas , Ruschke Tajas , Koch Andreas , Hochberger Christian 
Published: February 2021

AbstractCoarse Grained Reconfigurable Arrays (CGRAs) or Architectures are a concept for hardware accelerators based on the idea of distributing workload over Processing Elements. These processors exploit instruction level parallelism, while being energy efficient due to their simplistic internal structure. However, the incorporation into a complete computing system raises severe challenges at the hardware and software level. This article evaluates a CGRA integrated into a control engineering environment targeting a Xilinx Zynq System on Chip (SoC) in detail. Besides the actual application execution performance, the practicability of the configuration toolchain is validated. Challenges of the real-world integration are discussed and practical insights are highlighted.
Multidisciplinary expert consensus on secondary fracture prevention in Spain
Authors: Casado E. , Blanch J. , Carbonell C. , Bastida J. C. , Pérez-Castrillón J. L. , Canals L. , Lizán L. 
Published: February 2021

Abstract
Summary
The study aimed to achieve expert consensus to optimize secondary fracture prevention in Spain. Relevant gaps in current patient management were identified. However, some aspects were considered difficult to apply. Future efforts should focus on those items with greatest divergences between importance and feasibility.

Purpose
To establish a Spanish multidisciplinary expert consensus on secondary fracture prevention.

Methods
A two-round Delphi consensus was conducted, guided by a Scientific Committee. The 43-item study questionnaire was designed from a literature review and a subsequent multidisciplinary expert group (n = 12) discussion. The first-round questionnaire, using a 7-point Likert scale, assessed the experts’ opinion of the current situation, their wish for items to happen, and their prognosis that items would be implemented within 5 years. Items for which consensus was not achieved were included in the second round. Consensus was defined as ≥ 75% agreement or ≥ 75% disagreement. A total of 102 experts from 14 scientific societies were invited to participate.

Results
A total of 75 (response rate 73.5%) and 69 (92.0%) experts answered the first and second Delphi rounds, respectively. Participants mean age was 51.8 years [standard deviation (SD): 10.1 years]; being 24.0% rheumatologists, 21.3% primary care physicians, 14.7% geriatricians, 8.0% internal medicine specialists, 8.0% rehabilitation physicians, and 8.0% gynecologists. Consensus was achieved for 79.1% of items (wish, 100%; prognosis, 58.1%). Effective secondary prevention strategies identified as requiring improvement included: clinical report standardization, effective hospital primary care communication (telephone/mail and case managers), health-related quality of life (HRQoL) questionnaires use, and treatment compliance monitoring (prognosis agreement 33.3%, 47.8%, 18.8%, and 55.1%, respectively).

Conclusion
A consensus was reached by health professionals in their wish to implement strategies to optimize secondary fracture prevention; however, they considered some difficult to apply. Efforts should focus on those items with currently low application and those with greatest divergence between wish and prognosis.
Differences in Mental Health, Help-Seeking and Barriers to Care Between Civilians and Sworn Members Working in Law Enforcement: A Research Note
Authors: Martin Krystle , Siddiqui Alifa , Ricciardelli Rosemary , Lentz Liana , Carleton R. Nicholas 
Published: February 2021

Abstract
Recent Canadian research indicates 44.5% of public safety personnel (PSP) self-report symptoms consistent with at least one type of mental disorder; however, researchers have typically not focused on the mental wellness of civilians working within PSP sectors. Given that the number of civilians working in Canadian law enforcement organizations has doubled since 2003, with more than 30% of all police personnel in Canada being civilians, more research is needed to support this understudied sub-population within law enforcement. The current study used a survey to compare civilian members (n = 80) and sworn (n = 112) police officers working within a law enforcement organization on issues regarding mental disorders, perceived barriers to care and help-seeking behaviours. Results indicate that civilian members self-report a high prevalence of mental disorders and lower resilience compared with police officers in the same organization. Civilians reported similar barriers to accessing mental health compared with police officers but were less likely to indicate willingness to access supports within their place of employment. Our results support the need for equitable access to mental health resources for civilian staff working within law enforcement organizations.
Partial splenic embolization combined with endoscopic therapies and NSBB decreases the variceal rebleeding rate in cirrhosis patients with hypersplenism: a multicenter randomized controlled trial
Authors: Sun Xin , Zhang Anzhong , Zhou Tao , Wang Minghui , Chen Yong , Zhou Ting , Chen Xiaoning , Xiu Aiyuan , Peng Zhi , Cheng Baoquan , Liu Xiaofeng , Gao Yanjing 
Published: February 2021

Abstract
Background
Global research on endoscopic therapies in combination with partial splenic embolization (PSE) for variceal hemorrhage (VH) is limited. Therefore, we aimed to evaluate the efficacy and safety of endoscopy plus PSE (EP) treatment in comparison to endoscopic (E) treatment for the secondary prophylaxis of VH in cirrhosis patients with hypersplenism.

Methods
Cirrhosis patients with hypersplenism (platelet count < 100, 000/µL) and those who had recovered from an episode of VH were enrolled in a multicenter randomized controlled trial. The participants were randomly assigned into EP and E groups in a 1:1 ratio. The primary endpoint was variceal rebleeding, and the secondary endpoints were severe variceal recurrence and mortality during the 2-year follow-up. Hematological indices, serum biochemical parameters, and the Child–Pugh score were measured at each time point.

Results
From June 2016 to December 2019, 108 patients were enrolled in the study, among which 102 patients completed the protocol (51 in EP and 51 in E group). The rebleeding rate of the varices was significantly reduced in the EP group compared to that in the E group during the 2 years (16% vs. 31%, p < 0.001). The EP group showed a significantly lower variceal recurrence rate than the E group (22% vs. 67%, p < 0.001). The COX proportional hazard models revealed that grouping was an independent predictor for variceal rebleeding (H = 0.122, 95% CI 0.055–0.270, p < 0.001) and variceal recurrence (hazard ratio, H = 0.160, 95% CI 0.077–0.332, p < 0.001). The peripheral blood cell count, Child–Pugh class/score, albumin concentration, and coagulation function in the EP group improved significantly compared to the values observed in the E group at any time point (p < 0.05).

Conclusions
The EP treatment was more effective in preventing variceal rebleeding and variceal recurrence than the conventional E treatment during the secondary prophylaxis of VH in cirrhosis patients with hypersplenism. Furthermore, the EP treatment could significantly increase the peripheral blood cell count and albumin concentration and also improved the coagulation function and the Child–Pugh score.

Clinical trials registration
Trial registration number ClincialTrials.gov: NCT02778425. The URL of the clinical trial: https://clinicaltrials.gov/
Percentage tax designation institutions. On Sugden’s contractarian account
Authors: Silvestri Paolo 
Published: February 2021

Abstract“Percentage Tax Designation Institutions”, also known as “Percentage Philanthropy Laws”, are fiscal institutions through which taxpayers can freely designate a certain percentage of their income tax to organizations whose main activity is of public interest: churches, third-sector organizations, political parties, etc. A comprehensive explanation of such systems is still lacking. InThe Community of Advantage, Robert Sugden provides an original theoretical account of the Italian “8 × 1000” institution as one of those forms of regulation that “would be justified as ways of expanding opportunity for mutually beneficial transactions” and, more particularly, as a liberal and “contractarian approach to the provision of public goods”. This article is an attempt to expand and deepen the understanding not only of the 8 × 1000 but also of the 5 × 1000 and 2 × 1000 institutions, by reflecting on and possibly refining Sugden’s contractarian account, at least with regard to the part that relies on and develops the voluntary exchange tradition (Wicksell, Lindahl and Buchanan). To remain faithful to two normative premises of Sugden’s approach—the opportunity criterion and the correlated freedom of choice—we must introduce some theoretical adjustments to take into due account the way in which taxpayers’ freedoms—not only freedom of choice but also autonomy—are affected by default rules and the related redistribution procedures. In addition, these institutions also go beyond the voluntary exchange tradition—insofar as they go beyond its basic assumptions: the benefit principle of taxation, taxpayers’ self-interest and the very logic of exchange—and, at the same time, they can be read as a new form of voluntary tax justice.
Rapunzel Syndrome in a Seven-Year-Old Girl
Authors: Gupta Aviral , Mishra Sarvesh C. , Upadhyay Vijay D. , Kanneganti Pujana 
Published: February 2021

AbstractRapunzel syndrome is a rare entity with less than hundred case reports cited in the literature. In this, there is presence of a trichobezoar in the stomach which extends into the small intestine or beyond. It can typically cause abdominal pain and nausea, but can also present as an asymptomatic abdominal mass, progressing to abdominal obstruction and perforation. Many of these patients have associated psychiatric disorder. The gold standard for diagnosis is upper gastrointestinal endoscopy and treatment is surgical removal. Herein, we present surgical images of Rapunzel syndrome in a seven-year-old girl.
A follow-up study of a randomized controlled study evaluating safety and efficacy of leuprorelin acetate every-3-month depot for 2 versus 3 or more years with tamoxifen for 5 years as adjuvant treatment in premenopausal patients with endocrine-responsive breast cancer
Authors: Kurebayashi Junichi , Shiba Eiichi , Toyama Tatsuya , Matsumoto Hiroshi , Okazaki Minoru , Nomizu Tadashi , Ohtake Tohru , Fujii Takaaki , Ohashi Yasuo 
Published: February 2021

AbstractBackgroundPreviously, we conducted the 5-year open-label, randomized controlled trial (RCT) of leuprorelin adjuvant therapy in post-operative premenopausal patients with endocrine-responsive breast cancer, which was a pilot study to investigate the optimal duration of leuprorelin treatment. Since, however, long-term outcomes became required for the adjuvant endocrine therapy, we performed this follow-up observation study.MethodsFollow-up observation study was performed up to 10th year after randomization, continuing RCT to evaluate the efficacy and safety of leuprorelin every 3 months for ≥ 3 versus 2 years, with daily tamoxifen for 5 years. Primary endpoints were disease-free survival (DFS) and 2-year landmark DFS.ResultsEligible patients (N = 222) were randomly assigned to receive leuprorelin for either 2 years (N = 112) or ≥ 3 years (N = 110) with tamoxifen. Leuprorelin treatment for ≥ 3 years versus 2 years provided no significant difference in DFS (HR 0.944, 95% CI 0.486–1.8392) or 2-year landmark DFS (N = 99 and 102 in 2-year and ≥ 3-year groups, HR 0.834, 0.397–1.753). In small, higher-risk subgroup (n = 17); however, 2-year landmark DFS in ≥ 3-year group was significantly longer (HR 0.095, 0.011–0.850) than that in 2-year group. The incidence of bone-related adverse events was around 5% in both groups.ConclusionsAdjuvant leuprorelin treatment for ≥ 3 years with tamoxifen only showed similar efficacy and safety profiles to those for 2 years in analyses among all patients but suggested greater benefit in higher-risk patients. No new safety signal was identified for long-term leuprorelin treatment.Trial registration numberNot applicable. This was an observational study.
Hydrogen Peroxide Oxidation Reaction on a 4-Mercaptopyridine Self-Assembled Monolayer on Au(111) Metallized by Platinum Nanoislands
Authors: Piescheck Mathias , Abdelrahman Areeg , Hermann Johannes M. , Müller Heiko , Jacob Timo , Kibler Ludwig A. 
Published: February 2021

AbstractA systematic investigation of the hydrogen peroxide oxidation reaction (HPOR) in phosphate buffer (pH = 7.3) on an Au(111) single crystal modified with a 4-mercaptopyridine self-assembled monolayer (SAM) has been conducted before and after metallization with Pt. While bare Au(111) shows considerable electrocatalytic activity towards the HPOR, the inhibition of the oxidation reaction after modification with the SAM implies that adsorbed 4-mercaptopyridine molecules do not catalyze the HPOR. However, SAM-modified Au(111) recovers catalytic activity for the HPOR already after a single metallization step fabricating Pt islands on-top. Hydrogen peroxide (HP) may then either react at the (non-metallic) Pt nanoislands or on reactivated Au sites, made accessible by structural changes of the SAM induced by the metallization. The shape of the voltammetric profiles for the HPOR on repeatedly metallized SAMs suggests that the contribution of Au to the total current density gradually diminishes with increasing Pt coverage while the contribution of the Pt islands increases. The electrochemical behavior is dominated by the Pt islands at a coverage of 0.5 ML obtained by three subsequent metallization steps.
Graphical abstract
Enhanced aging and thermal shock performance of Mn1.95−xCO0.21Ni0.84SrxO4 NTC ceramics
Authors: Li Haibing , Zhang Huimin , Thayil Slapley , Chang Aimin , Sang Xu , Ma Xiuhua 
Published: February 2021

AbstractThe Mn1.95−xCo0.21Ni0.84SrxO4(MCNS) (0 ≼x≼ 0.15) based negative temperature coefficient (NTC) materials are prepared by co-precipitation method. The replacement of Mn by Sr plays a critical role in controlling the lattice parameter, relative density, microstructure, and electrical properties. The lattice parameter and relative density increase with the increase of Sr content. A small amount of Sr restrains the grain growth and increases the bulk density. Moreover, the room resistivityρ25, material constantB25/50, activation energyEa, and temperature coefficientαvalues of MCNS ceramics are influenced by the Sr content and ranged in 1535.0–2053.6 Ω·cm, 3654–3709 K, 0.3149–0.3197 eV, and (−4.173%)–(−4.111%), respectively. The X-ray photoelectron spectroscopy (XPS) results explain the transformation of MCNS ceramics from n- to p-type semiconductors. The conduction could arise from the hopping polaron between Mn3+/Mn4+and Co2+/Co3+in the octahedral sites. The impedance data analysis also discusses the conduction mechanism of the MCNS ceramic, whereas grain resistance dominates the whole resistance of the samples. Furthermore, the aging coefficient (ΔR/R) of MCNS ceramics is found to be < 0.2%, which indicates the stable distribution of cations in the spinel. Finally, the MCNS ceramics demonstrate excellent thermal durability with < 1.3% of resistance shift after100 thermal shock cycles.
Simultaneous energy harvesting and tribological property improvement
Authors: Wang Xiaofan , Mo Jiliang , Ouyang Huajiang , Xiang Zaiyu , Chen Wei , Zhou Zhongrong 
Published: February 2021

AbstractIn this study, piezoelectric elements were added to a reciprocating friction test bench to harvest friction-induced vibration energy. Parameters such as vibration acceleration, noise, and voltage signals of the system were measured and analyzed. The results show that the piezoelectric elements can not only collect vibration energy but also suppress friction-induced vibration noise (FIVN). Additionally, the wear of the friction interface was examined via optical microscopy (OM), scanning electron microscopy (SEM), and white-light interferometry (WLI). The results show that the surface wear state improved because of the reduction of FIVN. In order to analyze the experimental results in detail and explain them reasonably, the experimental phenomena were simulated numerically. Moreover, a simplified two-degree-of-freedom numerical model including the original system and the piezoelectric system was established to qualitatively describe the effects, dynamics, and tribological behaviors of the added piezoelectric elements to the original system.
Non-linear MHD convective flow of Carreau nanofluid over an exponentially stretching surface with activation energy and viscous dissipation
Authors: Babu K. S. Srinivasa , Parandhama A. , Vijaya R. Bhuvana 
Published: February 2021

AbstractNumerical approach for a non-linear mixed convective magnetohydrodynamic two-dimensional Carreau nanofluid through an exponentially permeable stretching surface with viscous dissipation and velocity slip under the influence of Arrhenius activation energy in chemical reaction is reported. The effects of thermophoresis and Brownian motion are considered. The governing nonlinear equations of this model are transmuted into ODE’s through similarity variables and solved them with a shooting method based on R-K 4th order. Responses of fluid velocity, transfer rates (heat and mass) versus pertinent parameters of the problem for suitable values are obtained and the computational calculations for friction coefficient, Nusselt number and Sherwood number for the both suction and injections regions are presented in plots and tables. It is found that fluid velocity is an increasing function of Weissenberg number. Momentum boundary layer thickness is depressed by magnetic field impact. Increasing trend in Carreau fluid temperature is noticed due to larger values of thermophoresis and Brownian motion effects. Concentration field is a decreasing function of Brownian motion but an increasing function of thermophoresis. Activation energy augments the concentration curves and lowered by Schmidt number. Comparison of the results is made with already published results and we got good agreement.