bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neutralization of VOCs including Delta one year post COVID-19 or vaccine
Authors: Havervall Sebastian , Marking Ulrika , Gordon Max , Ng Henry , Greilert-Norin Nina , Lindbo Sarah , Blom Kim , Nilsson Peter , Phillipson Mia , Klingström Jonas , Mangsbo Sara , Åberg Mikael , Hober Sophia , Thålin Charlotte 
Published: August 2021

AbstractBackgroundSARS-CoV-2 variants, such as Alpha, Beta, Gamma and Delta, are raising concern about the efficiency of neutralizing antibodies (NAb) induced by wild-type infection or vaccines based on the wild-type spike.MethodsWe determined IgG and NAb against SARS-CoV-2 variants one year following mild wild-type infection (n=104) and two-dose regimens with BNT162b2 (BNT/BNT) (n=67), ChAdOx1 (ChAd/ChAd) (n=82), or heterologous ChAdOx1 followed by BNT162b2 (ChAd/BNT) (n=116).FindingsWild type spike IgG and NAb remained detectable in 80% (83/104) of unvaccinated participants one year post mild infection. The neutralizing capacity was similar against wild type (reference), Alpha (0.95 (0.92-0.98) and Delta 1.03 (0.95-1.11) but significantly reduced against Beta (0.54 (0.48-0.60)) and Gamma 0.51 (0.44-0.61). Similarly, BNT/BNT and ChAd/ChAd elicited sustained capacity against Alpha and Delta (1.01 (0.78-1.31) and 0.85 (0.64-1.14)) and (0.96 (0.84-1.09) and 0.82 (0.61-1.10) respectively), with reduced capacity against Beta (0.67 (0.50-0.88) and 0.53 (0.40-0.71)) and Gamma (0.12 (0.06-0.27) and 0.54 (0.37-0.80)). A similar trend was found following ChAd/BNT (0.74 (0.66-0.83) and 0.70 (0.50-0.97) against Alpha and Delta and 0.29 (0.20-0.42) and 0.13 (0.08-0.20) against Beta and Gamma).InterpretationPersistent neutralization of the wide-spread Alpha and Delta variants one year after wild-type infection may aid vaccine policy makers in low-resource settings when prioritizing vaccine supply. The reduced capacity of neutralizing Beta and Gamma strains, but not the Alpha and Delta strains following both infection and three different vaccine regimens argues for caution against Beta and Gamma-exclusive mutations in the efforts to optimize next generation SARS-CoV-2 vaccines.FundingA full list of funding bodies that contributed to this study can be found in the Acknowledgements section
B and T cell responses after a third dose of SARS-CoV-2 vaccine in Kidney Transplant Recipients
Authors: Schrezenmeier Eva , Rincon-Arevalo Hector , Stefanski Ana-Luisa , Potekhin Alexander , Staub-Hohenbleicher Henriette , Choi Mira , Bachmann Friederike , Pross Vanessa , Hammett Charlotte , Schrezenmeier Hubert , Ludwig Carolin , Jahrsdörfer Bernd , Lino Andreia C. , Eckardt Kai-Uwe , Kotsch Katja , Dörner Thomas , Budde Klemens , Sattler Arne , Halleck Fabian 
Published: August 2021

AbstractBackgroundAccumulating evidence suggests that solid organ transplant recipients, as opposed to the general population, show strongly impaired responsiveness towards standard SARS-CoV-2 mRNA-based vaccination, demanding alternative strategies for protection of this vulnerable group.MethodsIn line with recent recommendations, a third dose of either heterologous ChAdOx1 (AstraZeneca) or homologous BNT162b2 (BioNTech) was administered to 25 kidney transplant recipients (KTR) without humoral response after 2 doses of BNT162b2, followed by analysis of serological responses and vaccine-specific B- and T-cell immunity.Results9/25 (36%) KTR under standard immunosuppressive treatment seroconverted until day 27 after the third vaccination, while one patient developed severe COVID-19 infection immediately after vaccination. Cellular analysis seven days after the third dose showed significantly elevated frequencies of viral spike protein receptor binding domain specific B cells in humoral responders as compared to non-responders. Likewise, portions of spike-reactive CD4+ T helper cells were significantly elevated in seroconverting patients. Furthermore, overall frequencies of IL-2+, IL-4+ and polyfunctional CD4+ T cells significantly increased after the third dose, whereas memory/effector differentiation remained unaffected.ConclusionsOur data suggest that a fraction of transplant recipients benefits from triple vaccination, where seroconversion is associated with quantitative and qualitative changes of cellular immunity. At the same time, the study highlights that modified vaccination approaches for immunosuppressed patients still remain an urgent medical need.Significance statementProtection of solid organ transplant recipients against SARS-Cov-2 by vaccination remains an unmet need given the low immunogenicity of available vaccines in the presence of immunosuppression. Administration of a third dose to 25 kidney transplant recipients (KTR) resulted in seroconversion in 36% of patients, associated with significant quantitative and functional changes within the spike-antigen-specific B-cell- and CD4+ T-helper cell compartment. Our data support the need for individual humoral monitoring of immunosuppressed individuals after vaccination as well as continued efforts to adapt vaccination protocols for this at-risk group.
Hybrid immunity improves B cell frequency, antibody potency and breadth against SARS-CoV-2 and variants of concern
Authors: Andreano Emanuele , Paciello Ida , Piccini Giulia , Manganaro Noemi , Pileri Piero , Hyseni Inesa , Leonardi Margherita , Pantano Elisa , Abbiento Valentina , Benincasa Linda , Giglioli Ginevra , De Santi Concetta , Fabbiani Massimiliano , Rancan Ilaria , Tumbarello Mario , Montagnani Francesca , Sala Claudia , Montomoli Emanuele , Rappuoli Rino 
Published: August 2021

ABSTRACTTo understand the nature of the antibody response to SARS-CoV-2 vaccination, we analyzed at single cell level the B cell responses of five naïve and five convalescent people immunized with the BNT162b2 mRNA vaccine. Convalescents had higher frequency of spike protein specific memory B cells and by cell sorting delivered 3,532 B cells, compared with 2,352 from naïve people. Of these, 944 from naïve and 2,299 from convalescents produced monoclonal antibodies against the spike protein and 411 of them neutralized the original Wuhan SARS-CoV-2 virus. More than 75% of the monoclonal antibodies from naïve people lost their neutralization activity against the B.1.351 (beta) and B.1.1.248 (gamma) variants while this happened only for 61% of those from convalescents. The overall loss of neutralization was lower for the B.1.1.7 (alpha) and B.1.617.2 (delta) variants, however it was always significantly higher in those of naïve people. In part this was due to the IGHV2-5;IGHJ4-1 germline, which was found only in convalescents and generated potent and broadly neutralizing antibodies. Overall, vaccination of seropositive people increases the frequency of B cells encoding antibodies with high potency and that are not susceptible to escape by any of the four variants of concern. Our data suggest that people that are seropositive following infection or primary vaccination will produce antibodies with increased potency and breadth and will be able to better control SARS-CoV-2 emerging variants.
From the ground up: growing an Australian Aboriginal cultural festival into a live musical community
Authors: Ryan Robin , Williams Jasmin , Simpson Alison 
Published: August 2021

PurposeThe purpose is to review the formation, event management, performance development and consumption of South East Australia’s inaugural 2018 Giiyong Festival with emphasis on the sociocultural imaginary and political positionings of its shared theatre of arts.Design/methodology/approachA trialogue between a musicologist, festival director and Indigenous stakeholder accrues qualitative ethnographic findings for discussion and analysis of the organic growth and productive functioning of the festival.FindingsAs an unprecedented moment of large-scale unity between First and non-First Nations Peoples in South East Australia, Giiyong Festival elevated the value of Indigenous business, culture and society in the regional marketplace. The performing arts, coupled with linguistic and visual idioms, worked to invigorate the Yuin cultural landscape.Research limitations/implicationsAdditional research was curtailed as COVID-19 shutdowns forced the cancellation of Giiyong Festival (2020). Opportunities for regional Indigenous arts to subsist as a source for live cultural expression are scoped.Practical implicationsMusic and dance are renewable cultural resources, and when performed live within festival contexts they work to sustain Indigenous identities. When aligned with Indigenous knowledge and languages, they impart central agency to First Nations Peoples in Australia.Social implicationsThe marketing of First Nations arts contributes broadly to high political stakes surrounding the overdue Constitutional Recognition of Australia's Indigenous Peoples.Originality/valueThe inclusive voices of a festival director and Indigenous manager augment a scholarly study of SE Australia's first large Aboriginal cultural festival that supplements pre-existing findings on Northern Australian festivals.
AAA screening in adults with ASD: a retrospective cohort study
Authors: Adamou Marios , Jones Sarah Louise , Wetherhill Stephanie 
Published: August 2021

Purpose
The Adult Asperger Assessment (AAA), comprising the Autism Questionnaire, the Empathy Quiotient and the Relatives Questionnaire is a commonly used screening tool designed to identify adults who may benefit from a further clinical assessment for autism spectrum disorder. The purpose of this paper is to investigate the usefulness of this screening measure in a clinical setting.

Design/methodology/approach
This retrospective cohort study comprised of 192 service users referred for diagnostic assessment of Autism by a specialist service of the National Health Service. The authors evaluated the diagnostic accuracy of the AAA by investigating if the Autism Questionnaire, the Empathy Quiotient and the Relatives Questionnaire were able to predict the diagnostic outcome of Autism in a clinical setting.

Findings
Scores from the Relatives Questionnaire can accurately predict diagnostic outcome. No evidence of accuracy for the Autism Questionnaire or the Empathy Quotient was apparent. Based on the findings, the authors recommend clinicians are cautious when interpreting results of the AAA.

Research limitations/implications
It should be acknowledged that the results may not be generalisable to whole populations. Also, the authors used the full item versions of the scales; therefore, the findings are most applicable to studies which did similar.

Originality/value
This study highlights the need for investigation into the lack of validation of commonly used screening measures in autistic populations.
Using clinical audit to improve the quality of mental health-care services for people with learning disabilities
Authors: da Costa Edward , Adams Danielle , Salmeh Munzer , Mahmoud Omar , Yetkili Ekim 
Published: August 2021

Purpose
The over-reliance on psychotropic medication for the management of patients with learning disabilities with behaviour that challenges is well documented.This paper aims to discuss the application of the methodology of clinical audit within community learning disability mental health services to adapt interventions including optimising prescribing practice and behavioural interventions aiming to reduce behaviour that challenges in people with learning disabilities.

Design/methodology/approach
Questionnaire-based review of documentation in electronic patient records, covering relevant audit standards in line with NICE and Royal College of Psychiatrists, was carried out in the North Essex Community Learning Disability Service, Hertfordshire Partnership NHS Foundation Trust. The audit included patients on the caseload of consultant psychiatrists.

Findings
The audit demonstrated that the prescribing of psychotropic medication was within BNF maximum limits for all patients, evidence of “consent” procedures was being followed in the majority, and there was some evidence of deprescribing attempts.Improvement was required in several areas e.g. undocumented off label prescribing in a significant proportion of patients. Objective measures to record the severity of behaviours and the effects of the medication were being used by clinicians in only a small proportion of patients. A significant proportion of patients have prescribed medication in the absence of appropriate psychological or environmental interventions.

Originality/value
As a result of the audit findings, the action plan made recommendations such as the development of a database for tracking the prescribing of psychotropic medicines and routine use of standardised measures. This action has been supported by the pharmacy team. Positive developments include a clinical psychologist taking on the role of leading the development of behavioural intervention strategies.
Measuring agri-food supply chain performance: insights from the Peruvian kiwicha industry
Authors: Ramos Edgar , Coles Phillip S. , Chavez Melissa , Hazen Benjamin 
Published: August 2021

PurposeAgri-food firms face many challenges when assessing and managing their performance. The purpose of this research is to determine important factors for an integrated agri-food supply chain performance measurement system.Design/methodology/approachThis research uses the Peruvian kiwicha supply chain as a meaningful context to examine critical factors affecting agri-food supply chain performance. The research uses interpretative structural modelling (ISM) with fuzzy MICMAC methods to suggest a hierarchical performance measurement model.FindingsThe resulting kiwicha supply chain performance management model provides insights for managers and academic theory regarding managing competing priorities within the agri-food supply chain.Originality/valueThe model developed in this research has been validated by cooperative kiwicha associations based in Puno, Peru, and further refined by experts. Moreover, the results obtained through ISM and fuzzy MICMAC methods could help decision-makers from any agri-food supply chain focus on achieving high operational performance by integrating key performance measurement factors.
Simple use of the Maclaurin series method for linear and non-linear differential equations arising in circuit analysis
Authors: Khan Yasir , Faraz Naeem 
Published: August 2021

Purpose
The purpose of this paper is to investigate the circuit analysis differential equations, which play an important role in the field of electrical and electronic engineering, and it was necessary to propose a very simple and direct method to obtain approximate solutions for the linear or non-linear differential equations, which should be simple for engineers to understand.

Design/methodology/approach
This paper introduces a simple novel Maclaurin series method (MSM) to propose an approximate novel solution in the area of circuit analysis for linear and non-linear differential equations. These equations describe the alternating current circuit of the resistor–capacitor, which evaluates the effect of non-linear current resistance. Linear and non-linear differential equations are evaluated as a computational analysis to assist the research, which reveals that the MSM is incredibly simple and effective.

Findings
Simulation findings indicate that the achieved proposed solution using the novel suggested approach is identical to the exact solutions mentioned in the literature. As the Maclaurin series is available to all non-mathematicians, this paper reflects mostly on theoretical implementations of the numerous circuit problems that occur in the field of electrical engineering.

Originality/value
A very simple and efficient method has been proposed in this paper, which is very easy to understand for even non-mathematicians such as engineers. The paper introduced a method of the Maclaurin series to solve non-linear differential equations resulting from the study of the circuits. The MSM mentioned here will be a useful tool in areas of physical and engineering anywhere the problem of the circuits is studied.
Constructing economic taxonomy reflecting firm relationships based on news reports
Authors: Zhou Zhi , Mu Xiangming , Lin Xin 
Published: August 2021

PurposeThis paper aims to propose a novel approach to constructing an economic taxonomy that demonstrates the complex relationships between firms, which are not fully revealed by traditional industry classification systems such as the NAICS or ICB.Design/methodology/approachBased on narrative economic theory, data from CNBC news reports between 01/01/2019 and 03/27/2019 regarding four selected firms, namely, Walmart, Amazon, Netflix and Boeing, were analyzed and coded as the basis to guide the construction of a firm-to-firm relationship taxonomy.FindingsThe relationships between firms are more complex than the simple relationships defined by the traditional classification systems with yes or no in terms of production process (NAICS) or major profit resource (ICB). Based on the sample firms, the authors proposed a four-layer hierarchical taxonomy framework that quantitatively reveals the inherent contradictory relationships between firms, which the authors defined as competition vs consistency. The proposed taxonomy framework is sufficiently flexible to accommodate complex relationships between firms, and it is also adaptable to new information. Under both the competition and consistency categories in the taxonomy model, more detailed subcategories are further coded into two more layers quantitatively to represent the firms' nuanced relationships.Originality/valueThis study provides a novel atheoretical approach to reveal complex firm relationships utilizing narrative text data gathered from news media. The framework of the firm relationship taxonomy constructed in this study provides an alternative and supplementary approach to the classical industry classification systems that can quantitatively specify comprehensive and dynamic connections between firms.
Identifying the causes of waterlogging on people's perception towards a resilient community: a case study on Pabna Municipality, Bangladesh
Authors: Parvez Mazed , Sadat Nazmus , Tasnim Farhana , Nejhum Israt Jahan 
Published: August 2021

PurposePabna is suffering from waterlogging problems from ancient times. The previous Drainage Master Plan was failed due to the lack of reflection of the general people of Pabna Municipality. As a result, this study focuses on identifying the causes of waterlogging in people's eyes. This paper will help the local authority and planners eradicate the waterlogging problem and build a planned and resilient community.Design/methodology/approachBoth primary and secondary data were used for the study. Present drainage pattern, topology climatic elements were collected from the journals, websites and Municipal Ingratiated Development Plan (MIDP), Pabna-2008. The sample size was 246, and this respondent was surveyed. By the survey, the people's perception of waterlogging was collected. For that, five independent variables and one dependent variable were determined. These variables were determined by previous studies, reconnaissance survey of the study area. It used multiple linear regression and the correlation method; the causes of waterlogging were determined.FindingsThe study found solid waste disposal into the drainage, absence of operation and maintenance system, small discharge capacity with blocked in the current drains, nonappearance of combined drainage network of roadside drains and unplanned drainage system as the leading causes of waterlogging from the perception of the people. Also found that the absence of operation and maintenance system, solid waste disposal into the drainage and unplanned drainage system as the influencing causes on small discharge capacity with blocked in the current drains.Originality/valueThis study has focused on people's perceptions rather than secondary data. That is why this study will significantly impact eradicating the waterlogging problem from the Pabna Municipality and will carry out the core problems without any bias. This will lead to a sustainable, planned and resilient community.
Exploring the social-ecological factors related to physical activity participation among Black, Asian and minority ethnic immigrants
Authors: Katito Godi , Davies Emma 
Published: August 2021

PurposeDespite the health benefits of physical activity (PA), participation rates Black, Asian and minority ethnic (BAME) adults in the United Kingdom (UK) are low in comparison to the general population. This study aimed to explore the social-ecological factors related to PA participation among BAME immigrants.Design/methodology/approachSemi-structured interviews were carried out with 12 purposively selected adults from the BAME populace residing in one postcode district of a city in southern England.FindingsThe three main themes that developed from this study demonstrated that the barriers to PA participation among BAME were perceived to exist at intrapersonal, and environmental (social and physical) levels.Research limitations/implicationsUnderstanding these unique social-ecological factors may assist in intervention development.Originality/valueProminent barriers included intrapersonal factors such as deportation fear and cultural beliefs; and environmental factors such as the cost of accessing PA facilities. Length of residency appeared to be related to increased PA.
Key themes in consumer financial services research from 2000 to 2020: a bibliometric and science mapping analysis
Authors: Molina-Collado Arturo , Salgado-Sequeiros Jessica , Gómez-Rico Mar , Aranda García Evangelina , De Maeyer Peter 
Published: August 2021

PurposeThe paper aims to identify the major research themes in consumer financial services between 2000 and 2020, their relative magnitude and interrelationship, to identify which themes have been most influential and to map the evolution of the field and identify emerging and under-researched themes that are promising for future research.Design/methodology/approachThe core methodology is bibliometric analysis based on keyword co-occurrences. A total of 1,227 articles extracted from the Social Science Citation Index, Emerging Sources Citation Index and Scopus are used in the analysis. Key outputs of the SciMAT software are the research themes, and graphical outputs are called science mapping (evolution of the themes over time), strategic diagrams (visual representation of themes in a 2 × 2 grid) and cluster networks (themes and connected themes based on keyword co-occurrences).FindingsThe findings show that customer satisfaction, innovation, corporate social responsibility (CSR), Internet and consumer acceptance were the main so-called motor themes in the study period. Furthermore, five areas for further research are identified and discussed: Issues related to technology; marketing and consumer behavior; markets and industry; product and service development; and branding.Research limitations/implicationsBibliometric research allows the researcher to process large volumes of articles covering a broad scope, leading to rich and insightful results. However, for greater detail and nuance, the authors recommend supplementing the results of this study with a more focused and thorough qualitative literature review for each theme of interest.Originality/valueBibliometric analysis is under-used in management research. The authors are not aware of similar recent work in consumer financial services. The main value of this paper lies in knowledge dissemination to a wider audience (including practitioners and researchers in adjacent areas) and providing a rigorous platform for identifying future research opportunities.