bluuebunny/crossref_metadata_2025_split huggingface dataset:
High Diagnostic and Prognostic Value of miRNAs Compared with the Carcinoembryonic
Antigen As A Traditional Tumor Marker
Authors: Yaghoubi Neda , Avval Farnaz Zahedi , Khazaei Majid , Sahebkar Amirhossein , Aghaee-Bakhtiari Seyed Hamid 
Published: June 2021

Abstract:
Early diagnosis and accurate prognosis are significant important challenges against effective treatment of
cancer and improving patient’s condition. Hitherto, many research works have tended to focus on the carcinoembryonic
antigen (CEA) to detect cancers and estimate the survival rates of patients with multiple cancer types, including
colorectal, breast, non-small cell lung, and pancreas cancer. Limited sensitivity and specificity of this traditional tumor
marker make it an inappropriate biomarker to diagnose cancer, especially in the early stages while several lines of
research have introduced miRNAs as reliable indicators of tumor initiation, development, and therapy response. Indeed,
miRNAs have unique properties that provide considerable benefits, such as discriminating benign diseases from
malignancies, predicting cancer development and progression, checking sensitivity to treatment, and initial detecting of
tumors. This review summarizes the relationships between miRNAs and CEA, the diagnostic significance of CEA in
combination with miRNAs, and the distinct advantages of miRNAs over CEA as tumor biomarkers. Advancement in
our current understanding of miRNAs is very essential to discover new and effective biomarkers for diagnostic, prognostic,
and therapeutic goals of cancer patients.
Antibacterial Activity of Indian Spices against the Pathogens Isolated from Wound Infection
Authors: Saruchi  , Saini Anjali , Kumar Vaneet 
Published: June 2021

Introduction:
Plants have been used for thousands of years to treat health disorders, to
prevent diseases including epidemics, to flavor and conserve food. It is estimated that 250 to 500
thousand plant species are present on the earth, out of which merely 10 percent are used as a
source of food by humans and animals.

Objective:
In the present work, antibacterial activity of five different Indian spices namely turmeric,
clove, pepper, cinnamon and garlic was investigated against pathogens isolated from
wound samples

Method:
The unknown bacteria were identified by different types of morphological and biochemical
techniques such as serial dilutions spread plate methods, morphological studies and biochemical
tests. The swabs of the patients were inoculated in 10 mL of sterile nutrient broth and
incubated at 37oC for 24 h. The antibacterial activities of these Indian spices were evaluated using
the disk diffusion method. A suspension of the microorganisms to be tested was spread on nutrient
agar and MacConkey agar medium. The filter paper discs were placed on the agar plates,
which were saturated with extract of spice. The plates were then incubated at 37oC for 24 h. The
zone of inhibition was determined post-incubation by evaluating the diameter of the zone of inhibition.

Results:
The antibacterial activities of these Indian spices were evaluated using the disk diffusion
method, and the inhibitory zones were recorded. It was quite evident from the result
that cinnamon had a larger inhibition zone against P1NA3, P1MAC1 and least for P2NA2.
Garlic exhibited a greater zone of inhibition against P2NA2, P3NA3 and least for P1MAC1.
Clove had a maximum zone of inhibition against P1MAC2 and least with P3NA3. These
spices displayed a zone of inhibition somewhat close to the control antibiotic drug, ampicillin.

Conclusion:
P1MNC2 showed a maximum zone of inhibition with clove (3 cm) at 100%. P2NA2
showed maximum antibacterial activity with garlic (3.6 cm) at 100% and minimum with cinnamon
(1.1cm) at 20%. P3NA3 presented maximum antibacterial activity result with garlic (4.2 cm)
at 100% and minimum with clove (1.2cm) at 20%. Spices are economical, more accessible to
most of the population in the world. So, medicinal plants should be encouraged as potential candidates
for new drugs.
Relationship Between Parenting Style and Establishment of Religious Characters at Taman Pendidikan Alquran (TPA) Masjid Alfurqon Desa Sikuliek Kecataman Koto Tangah Kota Padang
Authors: Guchi Gilang Ariesta , Sunarti Vevi 
Published: June 2021

This research was motivated by the low religious character of children studying at the Al-Furqon Mosque Education Park (TPA), Sikuliek Village, Koto Tangah District, Padang City. This is most likely due to ineffective and inaccurate parenting parents, which have a negative impact on the child's personality, especially in the development of religious character. Based on this phenomenon, the aim of this study is to describe the parenting parents of the parents in relation to the child, to describe the religious character of the child, and to determine the relationship between the parenting parentsof the parents and the development of the religious character of the child. Correlational quantitative analysis is the term for this form of study. All children who learned the Koran at the Al-Furqon Mosque Education Park were included in this report (TPA). Saturated samples were used as a sampling method. A questionnaire is the data collection method, and a list of statements is the data collection tool. The percentage formula and sperman rho were used in the data analysis technique. The results showed that low parenting parent, low religious character of children and there is a significant relationship between parenting parentswith the formation of children's religious character. Suggestions in this study are that parents are expected to be able to choose and sort out what parenting parents to apply to children, pay more attention to children and become role models for their children because the family environment is very much determined by the formation of children's religious character and the existence of cooperation between parents and administrators TPA to participate in motivating children to continuously attend lessons at the TPA so as to maximize the formation of children's religious character.Keywords: Parenting Parents, Religious Character
MEMBANDINGKAN CATATAN PERJALANAN PELANCONG DAN NISAN KUNO KERAJAAN PERLAK, ACEH TIMUR, ACEH
Authors: Ajis Ambo Asse 
Published: June 2021

The 11th century AD Armenian text entitled A Journals of the South China Sea refers to the tofonim Peureulak by the name Poure (Armenian) as a rich and valuable port. Marco Polo (1293 / late 13th century AD) was called Ferlec (Portuguese), which was a settlement with an Islamic population that was regularly visited by Islamic traders. The Negarakertagama manuscript of the 14th century AD mentions the name Parllak (Javanese) as one of the vassals of the Majapahit Kingdom. Likewise local texts, especially Hikayat Raja-Raja Pasai, mention that the existence of the Peureulak Kingdom ended when it merged into the power of the Samudera Pasai Kingdom (1297 AD) through the process of marriage. This paper aims to see whether the records of the above improvements have the support of archaeological remains, especially the pre-Pasai Ocean era. The research method is descriptive by comparing information with the existence of archaeological remains of two pieces of data that have the same space and time dimensions, namely the rise of the pre-13th century AD and archaeological remains in the form of ancient pre-Samudera Pasai tombstones. The final conclusion is that the results of the comparison of space and time dimensions show that there is a synchronization that confirms the record that saw the Muslim population in Peureulak before the establishment of the kingdom of Samudera Pasai, which is one of the earliest Islamic cities in Southeast Asia.
Teks berbahasa Armenia abad ke-11 Masehi berjudul Suatu Catatan Perjalanan di laut Cina Selatan menyebut toponim Peureulak dengan nama Poure (bahasa Armenia) sebagai pelabuhan yang kaya dan berharga. Marco Polo (1293/akhir abad ke-13 M) menyebutnya Ferlec (bahasa Portugis) yakni sebuah lokasi permukiman berpenduduk Islam yang rutin disinggahi pedagang Islam. Naskah Negarakertagama abad 14 menyebut nama Parllak (bahasa Jawa) sebagai salah satu vasal Kerajaan Majapahit. Demikian juga naskah lokal, khususnya Hikayat Raja-Raja Pasai menyebut eksistensi Kerajaan Peureulak berakhir ketika melebur ke dalam kekuasaan Kerajaan Samudera Pasai (1297 M) melalui proses pernikahan. Tulisan ini bertujuan ingin melihat apakah catatan para pelancong di atas memiliki dukungan tinggalan arkeologis khususnya era sebelum Samudera Pasai. Metode penelitian bersifat deskriptif dengan cara melakukan komparasi informasi dengan keberadaan tinggalan arkeologis dua buah data yang memiliki kedudukan dimensi ruang dan waktu yang sama, yakni catatan pelancong abad sebelum abad 13 dan tinggalan arkeologis berupa nisan-nisan kuno era sebelum Samudera Pasai. Kesimpulan akhirnya bahwa dari hasil perbandingan dimensi ruang dan waktu menunjukan ada singkronisasi membenarkan catatan para pelancong melihat adanya penduduk Islam di Peureulak sebelum berdirinya kerajaan Samudera Pasai, yakni satu kota paling awal yang terislamisasi di Asia Tenggara.
The Three Levels of Education in Site Design Course of Architecture
Authors: Shi Yuanyuan 
Published: June 2021

“Professional Guiding Standards for Advanced Education Architecture in University Undergraduate Students” (2013 edition) indicates that the education system of architecture should include a section on “environment and site.” It should involve six learning components which are concepts of site and environment, site terrain classifications, environment of two tendencies, elements involved in the sites, elements of environmental impact, and site design.[1] As site design (drawing) has become a significant topic in the examination of registered architects, many domestic architecture colleges have set up site design courses as independent ones. After more than ten years of exploration and research in developing the education system of site design courses, teaching experiences and achievements have been acquired. Site design courses have been gradually integrated with general plan design, registered architect examination, and architectural programming. Teachers have specified relevant learning goals in the regular daily curriculum in addition to the basic and vocational education of architecture. In this way, the site design course would be more in line with the educational goals of architecture. This paper aims to analyze the education of site design courses in hope of developing the future architectural education.
Kauzalita činitele ve světle kompatibilistické kritiky
Authors: Dvořák Petr 
Published: June 2021

Článek souhrnně odpovídá na vybrané podněty a námitky čtyř textů, jež polemizují s některými aspekty Dvořákovy knihy Kauzalita činitele (Togga 2020). Ve vztahu k článku J. Peregrina vysvětluje, proč nelze přijmout jeho řešení antinomie mezi svobodným rozhodováním a determinismem oddělením dvou druhů jazyků či výkladových rámců. Kritiku S. Sousedíka Dvořák považuje za založenou na příliš úzkém pojetí schopnosti. Odmítá to, že by z pojmu schopnosti plynulo, že ta může být determinována pouze něčím jiným, než je její nositel. Podstatnou část námitky D. Peroutky Dvořák přijímá a upřesňuje, nakolik je existence alternativních možností nutnou podmínkou svobodného charakteru rozhodování. Konečně, v polemice s V. Punčochářem se Dvořák snaží vyložit, ve kterém smyslu náhoda ruší svobodu a ve kterém nikoliv. Dále, autor nepovažuje epistemické alternativy za dostatečné pro skutečnou svobodu rozhodování.
Analisis Sentimen Pindah Ibu Kota Berbasis Naive Bayes Classifier
Authors: Arsi Primandani , Kusuma Bagus Adhi , Nurhakim Azizan 
Published: June 2021

Perkembangan media sosial memudahkan pengguna dalam percepatan akses informasi di internet. Akses informasi yang awalnya sulit diperoleh begitu mudah sekarang ini. Media sosial memungkinkan penggunanya tidak hanya mengonsumsi tapi juga berpartisipasi, membuat, mengomentari dan menyebarkan beragam konten dalam berbagai format. Banyak media sosial yang berkembang di internet, salah satu yang banyak digemari adalah Twitter. Twitter merupakan media sosial yang memungkinkan para penggunanya untuk berinteraksi secara personal ataupun terbuka. Melalu fitur hashtag para pengguna Twitter dapat mengetahui topik yang sedang dibahas secara real-time. Selain itu kata kunci pada Twitter dapat pula menjadi sumber perbincangan oleh pengguna. Salah satu topik yang ramai diperbincangkan di Twitter adalah terkait issue pemindahan ibu kota Indonesia. Namun dibalik hal tersebut terdapat kontroversi dari pihak yang merasa pro dan kontra, masing-masing memiiki sudut pandang sendiri. Hal ini menyebabkan munculnya fenomena perdebatan khususnya di Twitter yang sebenarnya menunjukkan perhatian kolektif mengenai wacana publik. Kecenderungan pengguna Twitter dalam memposting konten dapat diketahui dengan cara analisa sentiment. Pada penelitian ini diusulkan metode Naive Bayes Classifier (NBC) untuk menganalisa sentimen terhadap wacana pemerintah di media massa online Twitter pada topik pemindahan ibukota Indonesia dengan cara mengklasifikasikan menjadi positif, dan negatif. Hasil penelitian ini menunjukkan bahwa nilai akurasi yang diperoleh sebesar 94,33%. Dengan dilakukannya analisa sentimen ini diharapkan dapat diketahui permasalahan yang terdapat pada kontroversi topik pemindahan ibukota, sehingga dapat dijadikan sebagai bahan evaluasi untuk kepentingan lebih lanjut.
Pemberdayaan Masyarakat Melalui Edukasi Kelompok Sebaya Sebagai Upaya Pencegahan Anemia Gizi Besi Pada Remaja
Authors: Astuti Rini Wuri , Suryani Isti 
Published: June 2021

Latar belakang : Anemia Gizi besi (AGB) merupakan salah satu masalah gizi yang banyak dijumpai di Indonesia khususnya pada remaja. Remaja putri beresiko tinggi mengalami anemia. Pencegahan anemia gizi besi pada remaja dapat dilakukan melalui pemberdayaan masyarakat melalui edukasi pada kelompok sebaya. Tujuan Khusus : Mengetahui pengaruh pemberdayaan masyarakat melalui edukasi kelompok sebaya terhadap pengetahuan dan sikap pencegahan anemia gizi besi pada remaja. Metode Penelitian : Penelitian ini merupakan penelitian quacy experimental dengan rancangan pre-post test with control group design. Penelitian ini bertempat di Desa Trimurti, Srandakan, Bantul. Populasi dalam penelitian adalah seluruh remaja putri. Analisis bivariat menggunakan uji Independent Sample T-Test dan uji Mann Whitney. Hasil : Ada peningkatan pengetahuan secara signifikan sebelum dan setelah intervensi edukasi kelompok sebaya pada kelompok perlakuan p=0,001 (p<0,05), dan kelompok kontrol p=0,037 (p<0,05). Nilai sikap sebelum dan setelah intervensi pada kelompok perlakuan berubah positif secara signifikan dengan nilai p=0,002 (p<0,05). Nilai sikap sebelum dan setelah intervensi pada kelompok kontrol berubah secara positif tetapi tidak signifikan dengan p=0,46 (p>0,05). Kesimpulan: Intervensi edukasi kelompok sebaya meningkatkan pengetahuan dan sikap anemia gizi besi secara signifikan.
Analisis dan Sinkronisasi Tabel Komposisi Pangan Aplikasi Nutrisurvey Versi Indonesia
Authors: Sulistiyono Priyo , Heriyanto Yanto , Priyadi Irfan , Putri Lisiana Fazriyani , Rilkiyanti Oetika 
Published: June 2021

Latar Belakang: Ahli gizi Indonesia masih banyak yang menggunakan aplikasi Nutrisurvey (NS) untuk menganalisis kandungan gizi pada bahan makanan dan resep makanan. Nutrisurvey Indonesia (2005) memiliki kekurangan berupa database nilai gizi pangan atau Food Composition Table (FCT) yang masih belum diperbaharui atau disinkronkan dengan Tabel Komposisi Pangan Indonesia (TKPI-2017). Hal ini menyebabkan terjadi ketidaksesuaian perhitungan estimasi nilai gizi pangan. Tujuan: mengetahui perbedaan; jenis pangan, jumlah zat gizi dan nilai gizi pangan pada aplikasi Nutrisurvey (NS-2005) dan TKPI-2017 dan melakukan pembaharuan pangkalan data NS. Metode: Jenis penelitian adalah deskriptif observasional, dengan menyelia perbedaan jenis pangan, jumlah zat gizi dan nilai gizi pangan. Pembaharuan pangkalan data aplikasi NS. Hasil: Jumlah jenis pangan di TKPI sebanyak 1.113 jenis dan Nutrisurvey sebanyak 934 jenis. Nutrisurvey sebanyak 43 zat gizi dan TKPI sebanyak 21 zat gizi. Perbedaan jumlah zat gizi pada keduanya sebesar 22 zat gizi. Nutrisurvey memiliki rerata nilai gizi pangan lebih tinggi daripada TKPI sebesar 34,3%. Hasil sinkronisasi menghasilkan Aplikasi Nutrisurvey dengan pangkalan data baru yang disebut Nutrisurvey-TKPI 2017 (NS-TKPI 2017). Kesimpulan: Nutrisurvey-TKPI 2017 dengan berbagai kelebihannya masih layak untuk digunakan oleh ahli gizi dan praktisi gizi. Nutrisurvey memiliki fitur yang cukup mendukung kerja ahli gizi.
KARAKTERISASI PHYSICO-THERMAL HYBRID BIOBRIKET LIMBAH BIOMASSA CANGKANG KOPI, TEMPURUNG KELAPA DAN BAKING FILTER DUST
Authors: Nurjannah Siti , Fona Zahra 
Published: June 2021

Kebutuhan energi yang semakin meningkat dan ketersedian bahan bakar yang menipis, mendorong perlunya inovasi terbaru untuk mendapatkan sumber energi yang dapat diperbaharui melalui bahan baku yang melimpah dan berkarakteristik sebanding. Tujuan penelitian ini adalah untuk menentukan karakteristik briket yang dibuat dari limbah biomassa Cangkang Kopi (CKP), Tempurung Kelapa (TPK) dan produk samping pabrik Baking Filter Dust (BFD) dengan menggunakan perekat kanji dan oli bekas. Bahan baku limbah biomassa CKP dan TPK dikeringkan dan dikarbonisasi dalam tunggu bertutup yang minim oksigen pada suhu 200-400oC. Kemudian arang CKP dan TPK dicrusher dan diayak dengan ukuran 60/80 mesh. Pencampuran bahan dilakukan dengan penambahan perekat sebanyak 4 gram. Pencetakan biobriket dilakukan dengan menggunakan alat pencetak silinder berdiameter 3,3 cm kemudian ditekan dengan press hidraulik dengan pemberian tekanan 150 kg/cm2. Dari hasil penelitian diperoleh hybrid briket dengan range densitas 0,908-1,141 g/cm3, kadar air 1,81-4,02 %, kadar abu 3,79-7,09 %.Kata kunci : Baking filter dust, cangkang kopi, hybrid briket, oli bekas, perekat kanji, tempurung kelapa.
МУЗИЧНА КОМПЕТЕНТНІСТЬ МАЙБУТНЬОГО ВЧИТЕЛЯ МУЗИКИ ЯК НАУКОВА ПРОБЛЕМА
Authors: Вікторова М. В. 
Published: June 2021

У статті розглянуто проблему музичної компетентності вчителя музики як основи його педагогічної діяльності.
Ключові слова: компетенція, компетентність, професіоналізм, професійні здібності, особові якості вчителя.

The article deals with the problem of musical competence of a teacher of music as a basis of his/her educational work.

Key words: competence, professionalism, professional capabilities, teacher personality qualities.
УПРАВЛІННЯ НАВЧАЛЬНИМ ПРОЦЕСОМ МАЙБУТНІХ СОЦІАЛЬНИХ ПЕДАГОГІВ ЗАСОБОМ ПРОЕКТНИХ ТЕХНОЛОГІЙ
Authors: Доброскок І. І. 
Published: June 2021

У статті розкрито зміст і структуру проектних технологій у процесі навчання майбутніх соціальних педагогів; шляхи їх ефективного упровадження. Проектні технології розглядаються як засіб управління навчальним процесом майбутніх фахівців в умовах магістратури.
Ключові слова: управління навчальним процесом, соціальні педагоги, проектні технології.
In the article the structure and content of design technology in the training of future social workers, their effective implementation. Project technologies are seen as a way to control the educational process of future professionals in the Judiciary.
Keywords: management of the learning process, social workers, design technology.
КОМП’ЮТЕРНІ ТА ІНФОРМАЦІЙНО-КОМУНІКАЦІЙНІ ТЕХНОЛОГІЇ ЯК ЗАСІБ ПІДВИЩЕННЯ ЯКОСТІ ПРОФЕСІЙНОЇ ПІДГОТОВКИ МАЙБУТНІХ УЧИТЕЛІВ НІМЕЦЬКОЇ МОВИ
Authors: Дрогайцев О. І. 
Published: June 2021

У статті розглянуто питання щодо застосування комп’ютерних та інформаційно-комунікаційних технологій у процесі навчання німецькій мові у вищій школі у світлі інформатизації та комп’ютеризації освіти, визначаються їх можливості в організації навчальної діяльності, узагальнюються деякі результати проведеної автором дослідно-експериментальної роботи.
Ключові слова: комп’ютерні технології, інформаційно-комунікаційні технології, інформатизація освіти, комп’ютеризація освіти, електронні засоби навчання.

This article examines the problems of using computer and information technologies in the process of studying German in higher education system, defines its capabilities in organizing the process of studying, summarizes the results of the experimental work.

Key words: computer technologies, information communicative technologies, informatization of the studying process, studying process computerization, electronic education means.
ФОРМУВАННЯ ЦІННІСНИХ ОРІЄНТАЦІЙ МАЙБУТНІХ ВЧИТЕЛІВ ЯК ЗАВДАННЯ ПЕДАГОГІЧНОЇ АКСІОЛОГІЇ
Authors: Калюжна Т. Г. 
Published: June 2021

У статті розглянуто процес формування ціннісних орієнтацій сучасного студентства педагогічних вузів, основні шляхи та методи духовного становлення особистості та модернізації сучасної освіти. Ключові слова: цінності, ціннісні орієнтації, педагогічна аксіологія, модернізація. In this article the author examines the formation of value orientations of today's college students, basic techniques and the way of spiritual identity formation and upgrading of modern education. Key words: values, value orientations, pedagogical axiology, modernization.
ПИТАННЯ ОРГАНІЗАЦІЇ НАВЧАЛЬНО-ПІЗНАВАЛЬНОЇ ДІЯЛЬНОСТІ СТУДЕНТІВ НА ЗАСАДАХ КОМПЕТЕНТНІСНОГО ПІДХОДУ
Authors: Карпюк В. А. 
Published: June 2021

У статті розглянуто особливості організації навчально-пізнавальної діяльності студентів, деякі аспекти організації навчально-пізнавальної діяльності на засадах компетентнісного підходу в умовах вищого навчального закладу.
Ключові слова: компетентність, компетентнісний підхід,навчально-пізнавальна діяльність, навчання, самоосвіта.

This article characterizes the organization of student educational-cognitive activity and deals with some aspects of the educational-cognitive activity organization on the basis of competence-based approach in terms of higher academic institutions.

Key words: competence, competence-based approach, teaching and cognitive activities, training, self-education
ФОРМУВАННЯ АКТИВНОЇ СОЦІАЛЬНОЇ ПОЗИЦІЇ СТУДЕНТІВ ЯК ПСИХОЛОГО-ПЕДАГОГІЧНА ПРОБЛЕМА
Authors: Качалова Т. Г. 
Published: June 2021

У статті уточнено поняття соціальної активності, визначені ключові якості соціально активної особистості, розглядаються умови та процес формування активної соціальної позиції студентів вищого навчального закладу
Ключові слова: категорія активності, зміст активної соціальної позиції,соціальна відповідальність особистості

The article clarifies the concept of social activity, defined as a key socially active person, considered the conditions and the formation of active social position of students of higher education.

Key words: category of activity, content of active social position, social responsibility of the individual.
УПРОВАДЖЕННЯ ІНФОРМАЦІЙНИХ ТЕХНОЛОГІЙ У САМОСТІЙНУ РОБОТУ КУРСАНТІВ І СТУДЕНТІВ ВВНЗ – ПОРЯДОК ОРГАНІЗАЦІЇ ТА ПРОВЕДЕННЯ
Authors: Кравчук О. І. , Гапеєва О. Л. 
Published: June 2021

Військово-педагогічний процес у ВВНЗ ґрунтується на парадигмі особистісно-орієнтовного навчання та передбачає цілеспрямовану й змістовну взаємодію того, хто вчить і того, хто навчається. В статті розглядається питання застосування інформаційних технологій у навчальному процесі як викладачами, так і тими, хто навчається, та взаємодія між ними під час самостійної роботи.
Ключові слова: інформаційні технології, інформатизація освітніх процесів у вищому навчальному закладі, електронне навчальне середовище, електронний підручник..
Military-pedagogical process is based on the paradigm Military High Educational School student-centered learning and provides a purposeful interaction of teacher and student. The article discusses the use of information technology in teaching by teachers and students, as well as the interaction between them during independent work.
Key words: information technology, informatisation in a high school, teaching enviroment of electric.