bluuebunny/crossref_metadata_2025_split huggingface dataset:
La relación espiritual del pueblo warao con Dani jobai
Authors: Vallejo Infante Henry Rafael 
Published: February 2021

En este artículo se establece una narración que hilvana diversos estudios sobre el pueblo warao a fin de avanzar en el entendimiento del imaginario que sustenta las formas de vivir, pensar y proyectar la relación espiritual de la mujer indígena con la Madre Tierra. El interés principal del estudio es identificar las milenarias prácticas migratorias del grupo étnico, como resultado de su cosmovisión, para así superar la mirada colonialista y punitiva con la que se pretende juzgar los desplazamientos poblacionales de los aborígenes por las extensiones orinoquenses, amazónicas y caribeñas. Se desarrolla un eje temático decolonialista desde los postulados de Palermo (s/f), Bigott (2011) y Lepe-Carrión (2014), centrado en la denuncia de los abusos del sistema capitalista y la dignificación de los saberes orales para reconstruir la historia de la milenaria población, fundamentados desde los planteamientos de Betancourt (1999), Ayala y Wilbert (2012), y Dieter (2008). Por ser una investigación de carácter etnográfico; se asumen las orientaciones metodológicas de LeComte & Goetz (1982), en coherencia con el paradigma socioconstruccionista planteado por Wiesenfeld (2001); para desarrollar la interpretación de los testimonios orales recogidos mediante la entrevista cualitativa se toma como referente a Márquez (2006 y 2009). En cuanto a los aportes finales para la construcción epistémica, se logró evidenciar el tejido multidimensional que fundamenta los vínculos espirituales de compensación, amor y honra por sus ancestros, Dani Jobai, el Gran Kanabo y los seres cósmicos y selváticos del territorio.
Hak dan Kewajiban Badan Permusyawaratan Desa Dalam Membentuk Pemerintahan Desa Yang Baik
Authors: Harahap Syahrul Bakti 
Published: February 2021

Badan Permusyawaratan Desa (BPD) adalah lembaga perwujudan demokrasi dalam penyeleggaraan pemerintahan desa. Badan permusyawaratan desa dapat dianggab sebagai parlemennya desa. Badan permusyawaratan desa merupakan lembaga baru di desa setelah otonomi daerah Indonesia. Wewenang badan permusyawaratan desa antara lain : membahas rancangan peraturan desa bersama kepala desa, melaksanakan pengawasan terhadap pelaksanaan peraturan desa dan peraturan kepala desa, mengusulkan pengangkatan dan pemberhentian kepala desa, membentuk panitia pemilihan kepala desa, menggali, menampung, menghimpun, merumuskan dan menyalurkan aspirasi masyarakat.Penelitian ini dilakukan dengan metode yuridis empiris yaitu penelitian secara langsung. Metode pengumpulan data dilakukan melalui observasi dan wawancara dengan dilengkapi angket agar data yang diperoleh lebih akurat. Populasi dan sampel dalam penelitian ini satu yakni ketua badan permusyawaratan desa, anggota badan permusyawaratan desa dan kepala desa, Desa Bengkel Kecamatan Perbaungan Kabupaten Serdang Bedagai. Analisa data dalam penelitian ini bersifat diskriptif analisis kualitatif, yaitu peneliti berusaha menggambarkan gejala sosial dengan undang-undang. Dimana ketentuan perundang-undangan dihubungkan dengan efekvitas hak dan kewaban Badan Permusyawaratan Desa dalam membentuk pemerintahan yang baik. Untuk pengambilan kesimpulan penelitian ini metode pendekatan kualitatif dengan pola pikir deduktif untuk mendapatkan gambaran Efektivitas hak dan kewajiban Badan Permusywaratan Desa dalam membentuk pemerintahan desa yang baik di Desa Bengkel Kecamatan Perbaungan Kabupaten Serdang Bedagai
Filosofía y metáfora
Authors: Vexler Talledo Magdalena 
Published: February 2021

Es un hecho que en el lenguaje filosófico aparecen una serie analogías y metáforas en sus diversas modalidades, por eso se plantea el problema de saber si su uso en este campo es legítimo o no; si la utilización de la metedora en Filosofía significa una invasión del lenguaje poético que introduce el error o la ambigüedad en ella, o mas bien su uso está justificado porque es un medio de expresión especial adecuado. para el lenguaje filosófico o porque es un medio de intelección de la realidad.
Hoy diversos planteamientos al respecto y éstos dependen de la concepción filosófica que asuma el autor, así como de la concepción que tenga de la naturaleza de la metáfora y sus funciones. Platón, por ejemplo, ha utilizado con mucha frecuencia alegorías parabólicas, mitos, etc., que son considerados formas, extensasde la metáfora, sin embargo no presenta en ninguno de sus escritosalguna teoría acerca de la metáfora y si su uso es legítimo o noen filosofía, aun cuando en muchos pasajes aparece mencionadaslas palabras imagen y comparación.
Material Development for English Tourism Subject Based on the Local Wisdom
Authors: Safitri Lia 
Published: February 2021

This article aimed to review the development of English Tourism subject by involving local wisdom. This article discusses about the definition of material development, the principles in material development and need analysis for material development. It also defined local wisdom as one the points in material development. The next discussion explains about the procedures of material development and discusses material development for English Tourism subject based on the local wisdom. Based on the review, this article also gives recommendations how to involve local wisdom in material development and how to develop meaningful material for English Tourism subject.

Keywords: material development, local wisdom, English for Tourism
Pengaruh Kepemimpinan dan Komitmen Organisasi Terhadap Kepuasan Kerja Karyawan Pada PT Integra Trustindo Utama Pekanbaru
Authors: Wahyuni Sri 
Published: February 2021

Tujuan penelitian ini untuk menganalisis pengaruh Kepemimpinan dan Komitmen Organisasi terhadap Kepuasan Kerja Karyawan Pada PT Integra Trustindo Pekanbaru. Populasi dalam penelitian ini adalah karyawan PT Integra Trustindo Utama Pekanbaru dengan 68 responden sebagai sampel yang dipilih menggunakan metode simple random sampling. Analisis data menggunakan analisis jalur melalui SPSS versi 24.0.
Hasil penelitian menunjukkan bahwa, Kepemimpinan berpengaruh positif dan signifikan terhadap Kepuasan Kerja. Komitmen Organisasi berpengaruh positif dan signifikan terhadap Kepuasan Kerja. Kepemimpinan dan Komitmen Organisasi berpengaruh positif dan signifikan terhadap kepuasan kerja. Koefisien Determinasi pada adjsted R2 sebesar 0,738. Artinya bahwa pengaruh kepemimpinan dan komitmen organisasi terhadap kepuasan kerja karyawan pada PT Integra Trustindo Utama Pekanbaru adalah sebesar 73,8%. Sedangkan sisanya 26,2% dipengaruhi oleh variabel lain yang tidak masuk dalam model ini.
DUKUNGAN TEMPAT KERJA TERHADAP PEMBERIAN ASI EKSKLUSIF BERDASARKAN PERMENKES NOMOR 33 TAHUN 2012 PADA IBU BEKERJA DI KANTOR BUMN (PT PLN) KOTA SEMARANG
Authors: Jamil Masfufatun , Sari Cempaka Kumala 
Published: February 2021

ASI (Air Susu Ibu) merupakan makanan yang memiliki gizi sempurna sesuai dengan kebutuhan bayi untuk pertumbuhan dan perkembangan yang optimal. Hak anak adalah hak asasi manusia dan untuk kepentingannya hak anak itu diakui dan dilindungi oleh hukum bahkan sejak dalam kandungan. Untuk hak bayi dalam mendapatkan asi eksklusif diatur dalam Pasal 128 Undang-Undang Kesehatan (UU Kesehatan) Nomor 36 tahun 2009 dan di jamin oleh Pemerintah melalui Peraturan Pemerintah (PP) Nomor 33 Tahun 2012 tentang Pemberian Air Susu Ibu Eksklusif (ASI Eksklusif). Dari hasil penelitian sebelumnya Program Magister Kedokteran Kerja Departemen Kedokteran Komunitas FKUI yang dilakukan di kantor BUMN, fasilitas menyusui yang dapat digunakan untuk memompa dan menyimpan ASI, belum memenuhi syarat. Apalagi program pembinaan laktasi, akses ke konsultan laktasi, dan materi edukasi tentang laktasi.Tujuan penelitian ini adalah dukuangan tempat kerja terhadap pemberian asi eksklusif berdasarkan Permenkes Nomor 33 Tahun 2012 pada ibu bekerja di Kantor BUMN (PT PLN) Kota Semarang.Penelitian ini dilaksanakan dengan metode analisa data yaitu dengan analisa kualitatif. Responden dalam penelitian ini adalah Kepala Bagian SDM PT PLN (Persero) UP 3, Bagian Kepegawian, karyawan yang menyusui. Hasil dari penelitian ini yaitu perusahaan bersikap positif terhadap program pemerintah tentang ASI eksklusif di tempat kerja. Hal ini didasarkan bahwa dengan perusahaan memberikan hak cuti karyawan untuk melahirkan yaitu selama 3 bulan dan memberikan kesempatan kepada karwayan yang masih menyusui bayinya untuk memerah ASI pada jam kerja sesuai dengan Undang-undang Ketenagakerjaan dan PP ASI Eksklusif. Ruangan yang digunakan untuk memerah ASI adalah ruangan dengan sekat yang biasa digunakan untuk istirahat di masing-masing kantor. Untuk peralatan pendukung tersedia lemari pendingin, tetapi lemari pendingin disediakan untuk umum, jadi ada beberapa yang menyimpan ASI perahnya ke lamri pendingin, ada yang juga yang menyimpan ASInya ke cooler bag ASI yang dibawa dari rumah. Untuk tempat memerah ASI sudah ada tetapi untuk ruangan dan peralatan belum sesuai dengan Permenkes Nomor 15 Tahun 2013 tentang Tata Cara Penyediaan Fasilitas Khusus Menyusui.
PENURUNAN TEKANAN DARAH MELALUI SENAM BUGAR LANSIA PADA LANSIA DENGAN HIPERTENSI
Authors: Sari Irma Mustika 
Published: February 2021

ABSTRAKLatar Belakang : Hipertensi banyak menyebabkan morbiditas pada setiap orang khususnya kepada lansia. Penanganan hipertensi dapat dilakukan dengan memperbaiki pola hidup serta dengan terapi non farmakologis yaitu dengan melakukan latihan fisik. Latihan fisik atau senam dapat membantu kekuatan pompa jantung agar bertambah, sehingga aliran darah bisa kembali lancar sehingga dapat meningkatkan faal jantung dan menurunkan tekanan darah. Adanya peningkatan tekanan darah pada lansia di Posyandu Lansia Pucangsawit sebanyak 44 orang yang belum pernah melakukan aktifitas fisik atau senam. Tujuan Penelitian : Menganalisis pengaruh senam bugar lansia terhadap tekanan darah pada penderita hipertensi. Metode Penelitian : Quasy eksperimental study dengan one group pretest-posttest design. Hasil Penelitian ; Hasil analisis menunjukkan tekanan darah sistolik pre test dan post test pada tabel didapatkan nilai p value 0,000 (p < 0,05), sedangkan dari hasil analisis pengukuran tekanan darah diastolik pre test dan post test didapatkan nilai p value 0,059 (p > 0,05). Simpulan : Ada perbedaan yang signifikan antara nilai tekanan darah sistolik pre test dan post test setelah dilakukan senam bugar lansia. Tidak ada perbedaan yang signifikan nilai tekanan darah diastolik pre test dan post test setelah dilakukan senam bugar lansia. Kata kunci : Senam bugar, lansia, hipertensi, tekanan darahABSTRACT REDUCTION OF BLOOD PRESSURE THROUGH ELDERLY FIT EXERCISES AMONG WITH HYPERTENSION Background: Hypertension causes a lot of morbidity in everyone, especially the elderly. handling of hypertension can be done by improving lifestyle and non-pharmacological therapy, namely by doing physical exercise. physical exercise or gymnastics can help increase the strength of the heart's pump, so that blood flow can return smoothly so that it can increase heart function and lower blood pressure. there was an increase in blood pressure in the elderly at Posyandu Lansia Pucangsawit as many as 44 people who had never done physical activity or gymnastics. Objective: To analyze the effect of exercise fitness on the elderly on blood pressure in patients with hypertension. Research Methods: Quasy experimental study with one group pretest-posttest design. Research result ; The analysis showed that the systolic blood pressure pre test and post test in the table obtained p value 0,000 (p <0.05), while the results of the analysis of diastolic blood pressure measurements pre test and post test obtained p value of 0.059 (p> 0.05). Conclusion: There is a significant difference between the systolic blood pressure values of the pre-test and post-test after doing fitness exercises for the elderly. There were no significant differences in the values of diastolic blood pressure pre-test and post-test after doing fitness exercises for the elderly.Keywords : Fit Exercise, elderly, hypertension, blood pressure
Dysbiosis of the Saliva Microbiome in Patients With Polycystic Ovary Syndrome
Authors: Li Na , Li Yangyang , Qian Chen , Liu Qing , Cao Wei , Ma Mo , He Rongbo , Chen Rourou , Geng Rong , Liu Yu 
Published: February 2021

Significant differences in salivary microbiota communities between polycystic ovary syndrome (PCOS) patients and healthy controls have been reported, and interestingly, some salivary microbiota exhibit diurnal oscillation in healthy people. However, whether the diurnal oscillation of salivary microbiota is present in PCOS patients is unknown. In this study, we describe the differences in the saliva microbiome between the PCOS group and the control group at different time points over 24 h. 16S rRNA gene amplicon sequencing was performed on salivary and fecal samples from 10 PCOS patients and 10 healthy controls, and salivary samples were collected at 6-h intervals over 24 h (Zeitgeber (ZT)0, ZT6, ZT12, and ZT18). Among the salivary samples, those from the PCOS group showed significant differences from those of the control group at each time point. Differences were evident in taxa level and metabolic pathways. Interestingly, we found that PCOS disrupted the diurnal rhythm of the salivary microbiota abundance, as determined in the group of healthy women. In addition, no similar changes were found in PCOS patients and controls between the oral and fecal microbiota, including differential microbiota at the phylum level. In this study, significant differences in the composition of the salivary microbiota between PCOS and healthy women were detected at different time points. We also showed that the diurnal rhythm of relative abundance of the salivary microbiota was disrupted in patients with PCOS, which might be related to development of oral-related diseases and systematic metabolic disorders.
How to Develop and Implement a Computerized Decision Support System Integrated for Antimicrobial Stewardship? Experiences From Two Swiss Hospital Systems
Authors: Catho Gaud , Centemero Nicolo S. , Waldispühl Suter Brigitte , Vernaz Nathalie , Portela Javier , Da Silva Serge , Valotti Roberta , Coray Valentina , Pagnamenta Francesco , Ranzani Alice , Piuz Marie-Françoise , Elzi Luigia , Meyer Rodolphe , Bernasconi Enos , Huttner Benedikt D. ,   The COMPASS Study Group
Published: February 2021

Background: Computerized decision support systems (CDSS) provide new opportunities for automating antimicrobial stewardship (AMS) interventions and integrating them in routine healthcare. CDSS are recommended as part of AMS programs by international guidelines but few have been implemented so far. In the context of the publicly funded COMPuterized Antibiotic Stewardship Study (COMPASS), we developed and implemented two CDSSs for antimicrobial prescriptions integrated into the in-house electronic health records of two public hospitals in Switzerland. Developing and implementing such systems was a unique opportunity for learning during which we faced several challenges. In this narrative review we describe key lessons learned.Recommendations: (1) During the initial planning and development stage, start by drafting the CDSS as an algorithm and use a standardized format to communicate clearly the desired functionalities of the tool to all stakeholders. (2) Set up a multidisciplinary team bringing together Information Technologies (IT) specialists with development expertise, clinicians familiar with “real-life” processes in the wards and if possible, involve collaborators having knowledge in both areas. (3) When designing the CDSS, make the underlying decision-making process transparent for physicians and start simple and make sure to find the right balance between force and persuasion to ensure adoption by end-users. (4) Correctly assess the clinical and economic impact of your tool, therefore try to use standardized terminologies and limit the use of free text for analysis purpose. (5) At the implementation stage, plan usability testing early, develop an appropriate training plan suitable to end users' skills and time-constraints and think ahead of additional challenges related to the study design that may occur (such as a cluster randomized trial). Stay also tuned to react quickly during the intervention phase. (6) Finally, during the assessment stage plan ahead maintenance, adaptation and related financial challenges and stay connected with institutional partners to leverage potential synergies with other informatics projects.
Experimental Investigation on the Separation Performance for a New Oil-Water Separator
Authors: Zhan Min , Yang Wanyou , Zhang Fenghui , Luo Changhua , Wu Huaxiao , Guo Peiwen , Shen Qiong , Zeng Xiaobo , Yan Changqi 
Published: February 2021

To reduce the cost of oil exploitation, it is necessary to promote the development of cyclones for oil-water separation due to the increase of the water content in produced fluids. However, there are some limitations and disadvantages for the conventional separation device including bulky settling tanks and hydrocyclones. In this paper, a new axial inlet separator with two reverse flow outlets and a downstream flow outlet is introduced. In addition, an experimental system was designed and fabricated to investigate the effects of inlet flow rate, oil fraction, and a controlled split ratio on separation performance. The separator maintains high separation efficiency within the experimental range, namely water flow rate (4–7 m3/h), and oil fraction (1%–10%). Furthermore, the results show that a higher water flow rate and oil fraction will affect the separation efficiency. The change of a pressure drop in the separator was analyzed as well. Moreover, the controlled split ratio is a serious operating parameter, and a larger controlled split ratio is conducive to the separation performance.
Identification of Potential Driver Genes Based on Multi-Genomic Data in Cervical Cancer
Authors: Xu Yuexun , Luo Hui , Hu Qunchao , Zhu Haiyan 
Published: February 2021

Background: Cervical cancer became the third most common cancer among women, and genome characterization of cervical cancer patients has revealed the extensive complexity of molecular alterations. However, identifying driver mutation and depicting molecular classification in cervical cancer remain a challenge.Methods: We performed an integrative multi-platform analysis of a cervical cancer cohort from The Cancer Genome Atlas (TCGA) based on 284 clinical cases and identified the driver genes and possible molecular classification of cervical cancer.Results: Multi-platform integration showed that cervical cancer exhibited a wide range of mutation. The top 10 mutated genes were TTN, PIK3CA, MUC4, KMT2C, MUC16, KMT2D, SYNE1, FLG, DST, and EP300, with a mutation rate from 12 to 33%. Applying GISTIC to detect copy number variation (CNV), the most frequent chromosome arm-level CNVs included losses in 4p, 11p, and 11q and gains in 20q, 3q, and 1q. Then, we performed unsupervised consensus clustering of tumor CNV profiles and methylation profiles and detected four statistically significant expression subtypes. Finally, by combining the multidimensional datasets, we identified 10 potential driver genes, including GPR107, CHRNA5, ZBTB20, Rb1, NCAPH2, SCA1, SLC25A5, RBPMS, DDX3X, and H2BFM.Conclusions: This comprehensive analysis described the genetic characteristic of cervical cancer and identified novel driver genes in cervical cancer. These results provide insight into developing precision treatment in cervical cancer.
Correlations Between Tumor Mutation Burden and Immunocyte Infiltration and Their Prognostic Value in Colon Cancer
Authors: Zhou Zhangjian , Xie Xin , Wang Xuan , Zhang Xin , Li Wenxin , Sun Tuanhe , Cai Yifan , Wu Jianhua , Dang Chengxue , Zhang Hao 
Published: February 2021

BackgroundColon cancer has a huge incidence and mortality worldwide every year. Immunotherapy could be a new therapeutic option for patients with advanced colon cancer. Tumor mutation burden (TMB) and immune infiltration are considered critical in immunotherapy but their characteristics in colon cancer are still controversial.MethodsThe somatic mutation, transcriptome, and clinical data of patients with colon cancer were obtained from the TCGA database. Patients were divided into low or high TMB groups using the median TMB value. Somatic mutation landscape, differentially expressed genes, and immune-related hub genes, Gene Ontology and KEGG, gene set enrichment, and immune infiltration analyses were investigated between the two TMB groups. Univariate and multivariate Cox analyses were utilized to construct a prognostic gene signature. The differences in immune infiltration, and the expression of HLA-related genes and checkpoint genes were investigated between the two immunity groups based on single sample gene set enrichment analysis. Finally, a nomogram of the prognostic prediction model integrating TMB, immune infiltration, and clinical parameters was established. Calibration plots and receiver operating characteristic curves (ROC) were drawn, and the C-index was calculated to assess the predictive ability.ResultsMissense mutations and single nucleotide polymorphisms were the major variant characteristics in colon cancer. The TMB level showed significant differences in N stage, M stage, pathological stage, and immune infiltration. CD8+ T cells, activated memory CD4+ T cells, activated NK cells, and M1 macrophages infiltrated more in the high-TMB group. The antigen processing and presentation signaling pathway was enriched in the high-TMB group. Two immune related genes (CHGB and SCT) were identified to be correlated with colon cancer survival (HR = 1.39, P = 0.01; HR = 1.26, P = 0.02, respectively). Notably, the expression of SCT was identified as a risk factor in the immune risk model, in which high risk patients showed poorer survival (P = 0.04). High immunity status exhibited significant correlations with immune response pathways, HLA-related genes, and immune checkpoint genes. Finally, including nine factors, our nomogram prediction model showed better calibration (C-index = 0.764) and had an AUC of 0.737.ConclusionIn this study, we investigated the patterns and prognostic roles of TMB and immune infiltration in colon cancer, which provided new insights into the tumor microenvironment and immunotherapies and the development of a novel nomogram prognostic prediction model for patients with colon cancer.