bluuebunny/crossref_metadata_2025_split huggingface dataset:
NETosis Markers in Pregnancy: Effects Differ According to Histone Subtypes
Authors: Fortier Mathieu , Bouvier Sylvie , Vincent Laura , Demattei Christophe , Mousty Eve , Herzog Marielle , Rommelaere Guillaume , Nouvellon Eva , Mercier Eric , Letouzey Vincent , Gris Jean-Christophe 
Published: January 2021

AbstractNETosis is an innate immune response occurring after infection or inflammation: activated neutrophils expel decondensed DNA in complex with histones into the extracellular environment in a controlled manner. It activates coagulation and fuels the risk of thrombosis. Human pregnancy is associated with a mild proinflammatory state characterized by circulatory neutrophil activation which is further increased in complicated pregnancies, placenta-mediated complications being associated with an increased thrombotic risk. This aberrant activation leads to an increased release of nucleosomes in the blood flow. The aim of our study was to initially quantify nucleosome-bound histones in normal pregnancy and in placenta-mediated complication counterpart. We analyzed the role of histones on extravillous trophoblast function. Circulating nucleosome-bound histones H3 (Nu.QH3.1, Nu.QH3PanCit, Nu.QH3K27me3) and H4 (Nu.QH4K16Ac) were increased in complicated pregnancies. In vitro using the extravillous cell line HTR-8/SVNeo, we observed that free recombinant H2B, H3, and H4 inhibited migration in wound healing assay, but only H3 also blocked invasion in Matrigel-coated Transwell experiments. H3 and H4 also induced apoptosis, whereas H2B did not. Finally, the negative effects of H3 on invasion and apoptosis could be restored with enoxaparin, a low-molecular-weight heparin (LMWH), but not with aspirin. Different circulating nucleosome-bound histones are increased in complicated pregnancy and this would affect migration, invasion, and induce apoptosis of extravillous trophoblasts. Histones might be part of the link between the risk of thrombosis and pregnancy complications, with an effect of LMWH on both.
Phase separation in a mixture of trapped charged Bose–Einstein condensates
Authors: Aksu S Seyyare , Subaşı A Levent , Ghazanfari Nader 
Published: January 2021

Abstract
We study the phase separation configurations and rotational properties of a mixture of two interacting charged Bose–Einstein condensates subjected to a magnetic field trapped in disc and Corbino geometries. We calculate the ground state energies of the azimuthal and radial phase separation configurations using the Gross–Pitaevskii and Thomas–Fermi approximations. We show that the results for the experimentally relevant system parameters of both approaches are in good agreement. For both geometries, an immiscible mixture with equal intracomponent interactions favors azimuthal phase separation for all intercomponent interactions. Only an imbalance in the intracomponent interactions can result in a transition to radial phase separation, for which the transition becomes sensitive to the shape of the trap. We present phase diagrams as functions of the inter- and intracomponent interactions. While radial phase separation is widely favoured in disc geometry, the azimuthal phase separation is favoured for narrower Corbino geometries. We explore the rotational properties of spatially separated condensates subjected to magnetic fields, studying their angular momenta and velocity fields. The quantization of circulation breaks down for azimuthal phase separation. In this case, the bulk region of the condensate continues to display superfluid flow behaviour, whereas the velocity field shows a rigid body behaviour along the phase boundaries.
Strong enhancement of Penning ionisation in cold Rydberg gases II: Tom and Jerry pairs for alkali-metal atoms
Authors: Zalam Alaa Abo , Bruvelis M , Miculis K , Beterov I I , Bezuglov N N , Ekers A , Fuso F 
Published: January 2021

Abstract
Penning ionisation (PI) processes involving pairs of Rydberg alkali-metal atoms, excited to different quantum states and experiencing dipole–dipole interactions, have a wide range of important properties in atomic physics. Within the framework of the semiclassical approximation, we have used both numerical and analytical approaches to examine the Penning autoionisation width dependence on the state quantum numbers in a quasi-molecule formed by the interacting partner atoms. We described the characteristics of optimal quantum numbers that lead to enhanced PI widths for the interacting Rydberg atom pairs of all alkali-metal atoms. The excited states of atoms in these pairs are asymmetric, resulting in a large atomic shell size difference: inspired by Efimov et al (2016 J. Phys. B: At. Mol. Opt. Phys.
49 125302), we call such a pair ‘Tom’ and ‘Jerry’ (for ‘big’ and ‘small’). Compared to symmetric pairs, the optimal asymmetric pairs display a significant (by several orders of magnitude) increase in the PI rate. This property makes PI a relevant source for producing charged particles in cold Rydberg systems that spontaneously evolve into cold plasma. Contrary to hydrogen atoms examined in (Efimov et al 2016 J. Phys. B: At. Mol. Opt. Phys.
49 125302), the difference in quantum defects in alkali-metal atoms results in a strong Penning width dependence on the orbital quantum numbers l of the quasi-molecule. In particular, alkali-metal atoms exhibit two PI channels associated with bound–bound optical transitions showing Δl = ±1—individual and closely spaced (doublet-like) configurations of optimal pairs. Furthermore, we demonstrate that the presence of Förster resonances can lead to a notable (up to five times) increase in the PI efficiency.
Thermal effects in field electron emission from idealized arrangements of independent and interacting micro-protrusions
Authors: Mofakhami Darius , Seznec Benjamin , Minea Tiberiu , Teste Philippe , Landfried Romaric , Dessante Philippe 
Published: January 2021

Abstract
Modelling studies of thermo-field electron emission (TFE) from protrusions at a cathode surface usually use simulations in 2D axial symmetry. Indeed, time-dependent simulations in 3D are very demanding in computation time. Often, 3D simulations have been restricted to stationary pure field electron emission to account for the drastic current decrease caused by electric field screening when the emitters are close. Little interest has therefore been granted to the heat exchanges occurring between nearby emitters. Although the temperature is a second-order parameter in TFE compared to the electric field, thermal effects become non-negligible in high current density regimes, where self-heating is well established. The present study focuses on the thermal effects occurring during the TFE from micro-protrusions. Our model considers a DC voltage but solves in time the temperature evolution coupling the heat equation and the current continuity equation. The protrusions are modelled as hemiellipsoids with 2D axial symmetry. Emission enhancement due to the increase of the temperature in the thermo-field regime compared to the pure field regime is detailed as a test case for isolated protrusions. Then, full 3D simulations are used to investigate the thermal coupling between multiple neighbouring protrusions via their outwards heat fluxes inside the cathode. The results show a higher current increase due to thermal coupling for dome-like protrusions with a low field enhancement factor. The current increases up to 13% of the total current for aspect ratios of 1, but this value is reached for an extreme applied electric field, hardly reachable in experiments. For sharper protrusions with higher field enhancement, the interaction range through the cathode being shorter, the thermal coupling is suppressed by electrostatic screening. Nevertheless, in arrangements of densely distributed field emitter, when the screening is compensated by a higher voltage, our model predicts the possibility of a moderate but noticeable thermal coupling even for sharp protrusions: a parametric study indicates up to 14.5% of the emitted current being caused by a thermal coupling through the cathode bulk, for protrusions with an aspect ratio of 10 under a fixed applied electric field of 0.4 GV m−1 in DC mode.
Selective electrooxidation of 2-propanol on Pt nanoparticles supported on Co3O4: an in-situ study on atomically defined model systems
Authors: Yang Tian , Kastenmeier Maximilian , Ronovský Michal , Fusek Lukáš , Skála Tomáš , Waidhas Fabian , Bertram Manon , Tsud Nataliya , Matvija Peter , Prince Kevin C , Matolín Vladimír , Liu Zhi , Johánek Viktor , Mysliveček Josef , Lykhach Yaroslava , Brummel Olaf , Libuda Jörg 
Published: January 2021

Abstract
2-Propanol and its dehydrogenated counterpart acetone can be used as a rechargeable electrofuel. The concept involves selective oxidation of 2-propanol to acetone in a fuel cell coupled with reverse catalytic hydrogenation of acetone to 2-propanol in a closed cycle. We studied electrocatalytic oxidation of 2-propanol on complex model Pt/Co3O4(111) electrocatalysts prepared in ultra-high vacuum and characterized by scanning tunneling microscopy. The electrocatalytic behavior of the model electrocatalysts has been investigated in alkaline media (pH 10, phosphate buffer) by means of electrochemical infrared reflection absorption spectroscopy and ex-situ emersion synchrotron radiation photoelectron spectroscopy as a function of Pt particle size and compared with the electrocatalytic behavior of Pt(111) and pristine Co3O4(111) electrodes under similar conditions. We found that the Co3O4(111) film is inactive towards electrochemical oxidation of 2-propanol under the electrochemical conditions (0.3–1.1 VRHE). The electrochemical oxidation of 2-propanol readily occurs on Pt(111) yielding acetone at an onset potential of 0.4 VRHE. The reaction pathway does not involve CO but yields strongly adsorbed acetone species leading to a partial poisoning of the surface sites. On model Pt/Co3O4(111) electrocatalysts, we observed distinct metal support interactions and particle size effects associated with the charge transfer at the metal/oxide interface. We found that ultra-small Pt particles (around 1 nm and below) consist of partially oxidized Pt
δ

+ species which show minor activity towards 2-propanol oxidation. In contrast, conventional Pt particles (particle size of a few nm) are mainly metallic and show high activity toward 2-propanol oxidation.
Direct band gap and strong Rashba effect in van der Waals heterostructures of InSe and Sb single layers
Authors: Fang Dangqi , Chen Siyu , Li Yaqi , Monserrat Bartomeu 
Published: January 2021

Abstract
Van der Waals heterostructures formed by stacking different types of 2D materials are attracting increasing attention due to new emergent physical properties such as interlayer excitons. Recently synthesized atomically thin indium selenide (InSe) and antimony (Sb) individually exhibit interesting electronic properties such as high electron mobility in the former and high hole mobility in the latter. In this work, we present a first-principles investigation on the stability and electronic properties of ultrathin bilayer heterostructures composed of InSe and Sb single layers. The calculated electronic band structures reveal a direct band gap semiconducting nature of the InSe/Sb heterostructures independent of stacking pattern. Taking spin–orbit coupling (SOC) into account, we find a large Rashba spin splitting at the bottom of conduction band, which originates from the atomic SOC with the symmetry breaking in the heterostructure. The strength of the Rashba spin splitting can be tuned by applying in-plane biaxial strain or an out-of-plane external electric field. The presence of large Rashba spin splitting together with a suitable band gap in InSe/Sb bilayer heterostructures make them promising candidates for spin field-effect transistor and optoelectronic device applications.
Anisotropic crack propagation and self-healing mechanism of freestanding black phosphorus nanosheets
Authors: Bui Thi-Xuyen , Fang Te-Hua , Lee Chun-I 
Published: January 2021

Abstract
In this study, an indentation simulation is employed to study the anisotropic crack propagation and re-forming mechanism of freestanding black phosphorus (FBP) nanosheets by molecular dynamics simulation. The results indicate that the size of the FBP nanosheet decides the crack direction as well as the von Mises stress concentration. It is found that crack directions are not influenced by temperature. With increasing specimen size, the crack propagation rate is nearly the same as at the first stage of crack formation, while in the later stage, cracking develops very quickly in larger specimens. Especially, small FBP nanosheets almost re-form in a short time at ambient temperature. However, after being destroyed, the larger specimen has no possibility of recovery. Besides, when increasing the number of layers of FBP, the energy stored by the top layer and the system undergoing deformation increases. In addition, the specimen with two fixed edges is less stable, leading to increased stress and decreased Young’s modulus compared with the specimen with four fixed edges.
Roll-to-roll nanoimprint lithography using a seamless cylindrical mold nanopatterned with a high-speed mastering process
Authors: Cates Nichole , Einck Vincent J , Micklow Lauren , Morère Jacobo , Okoroanyanwu Uzodinma , Watkins James J , Furst Stephen 
Published: January 2021

Abstract
The advanced optical and wetting properties of metamaterials, plasmonic structures, and nanostructured surfaces have been repeatedly demonstrated in lab-scale experiments. Extending these exciting discoveries to large-area surfaces can transform technologies ranging from solar energy and virtual reality to biosensors and anti-microbial surfaces. Although photolithography is ideal for nanopatterning of small, expensive items such as computer chips, nanopatterning of large-area surfaces is virtually impossible with traditional lithographic techniques due to their exceptionally slow patterning rates and high costs. This article presents a high-throughput process that achieves large-area nanopatterning by combining roll-to-roll (R2R) nanoimprint lithography (NIL) and nanocoining, a process that can seamlessly nanopattern around a cylinder hundreds of times faster than electron-beam lithography. Here, nanocoining is used to fabricate a cylindrical mold with nanofeatures spaced by 600 nm and microfeatures spaced by 2 μm. This cylindrical drum mold is then used on a R2R NIL setup to pattern over 60 feet of polymer film. Microscopy is used to compare the feature shapes throughout the process. This scalable process offers the potential to transfer exciting lab-scale demonstrations to industrial-scale manufacturing without the prohibitively high cost usually associated with the fabrication of a master mold.
Theory of circularly polarized harmonic generation using bi-colour lasers in underdense plasmas
Authors: Chitgar Z M , Adam R , Greb C , Lehrach A , Büscher M , Gibbon P 
Published: January 2021

Abstract
Circularly polarized (CP) extreme ultraviolet- and x-ray radiation is an essential tool for analyzing the magnetic properties of materials. Elliptically polarized high harmonic generation (HHG) has been demonstrated by focusing bi-chromatic (800 + 400 nm wavelengths), counter-rotating CP laser pulses into gas targets (Fleischer et al 2014 Nat. Photonics
8 543). More recent theoretical studies indicate that a bi-circular laser driver can also work in both under- and overdense plasmas with analogous selection rules to those in gases: for example, every third harmonic is suppressed and adjacent harmonics have opposite helicity for counter-polarized CP ω
0 and 2ω
0 pumps. In this work, an analytical theory of bi-circular HHG from underdense plasmas is formulated which provides quantitative predictions of harmonic efficiency scaling, selectivity and helicity for both co- and counter-polarized drivers of arbitrary frequency ratio. This is compared to a fully non-linear, one-dimensional fluid model and particle-in-cell simulations, showing good agreement with both.
Spatio-temporal evolutions of ion heat flux and radial electric field during internal transport barrier formation on JT-60U
Authors: Kin F , Itoh K , Yoshida M , Honda M , Kamada Y , Kamiya K , Narita E , Bando T 
Published: January 2021

Abstract
Spatio-temporal structures of ion heat flux and radial electric field are investigated on JT-60U to understand a mechanism of the internal transport barrier (ITB) formation. Contrary to the conventional argument that the ITB formation is due to the

E
×
B

flow shear suppressions on turbulence, we observe that the

E
×
B

shearing rate during the ITB formation is not enough for turbulence suppressions with

k

ρ
i

∼ 1. Another finding is that the ITB is formed simultaneously with abrupt decreases of ion heat flux in the global region (like the report in Neudatchine et al 1999 Plasma Phys. Control. Fusion
41 L39), and the gradient–flux relations are non-diffusively developed step by step. These observations suggest the importance of the change in the long-radial fluctuations, which is previously observed in JT-60U (Nazikian et al 2005 Phys. Rev. Lett.
94 135002). Therefore, the model of effects by non-uniformity of the radial electric field, under the condition where the scale separation is violated, is employed to explain such fluctuation quenching. Consistent results are obtained showing that the non-uniformity of the radial electric field effectively works on the fluctuations with long-radial wavelength and increases the temperature gradient. It seems natural that the suppression of the long-radial fluctuations drives the global transport improvement to form the ITB.
Effect of polarimetric nonregularity on the spin of three-dimensional polarization states
Authors: Gil José J , Friberg Ari T , Norrman Andreas , Setälä Tero 
Published: January 2021

Abstract
While the spin of two-dimensional polarization states admits a simple representation, its physical interpretation for three-dimensional (3D) mixed polarization states requires a more involved analysis. In this work, we address the spin structure of the electric field of a general 3D polarization state by taking advantage of the characteristic decomposition and the recently introduced notion of nonregularity associated with 3D states. We show that a nonregular polarization state necessarily has an additional spin component due to the state’s genuinely 3D nature, and both the orientation and magnitude of the spin are regulated by the degree of nonregularity. The results provide new physical insight into partially polarized evanescent and tightly focused light fields in which strong nonregular character has recently been demonstrated.
Resource conversion between operational coherence and multipartite entanglement in many-body systems
Authors: Ren Li-Hang , Gao Meng , Ren Jun , Wang Z D , Bai Yan-Kui 
Published: January 2021

Abstract
We establish a set of resource conversion relationships between quantum coherence and multipartite entanglement in many-body systems, where the operational measures of resource cost and distillation are focused. Under the multipartite incoherent operation, the initial coherence of single-party system bounds the maximal amounts of corresponding operational entanglement in an arbitrary bipartite partition as well as the genuine multipartite entanglement (GME) in many-body systems. Furthermore, the converted multipartite entanglement can be transferred to its subsystems and restored to coherence of a single party by means of local incoherent operations and classical communication, which constitutes a protocol of resource interconversion within the full incoherent operation scenario. As an example, we present a scheme for cyclic interconversion between coherence and GME in three-qubit systems without loss. Moreover, we analyze the property of bipartite and multipartite genuine multi-level entanglement by the initial coherence and investigate multipartite resource dynamics in the conversion.
A passive BCI for monitoring the intentionality of the gaze-based moving object selection
Authors: Zhao Darisy G , Vasilyev Anatoly N , Kozyrskiy Bogdan L , Melnichuk Eugeny V , Isachenko Andrey V , Velichkovsky Boris M , Shishkin Sergei L 
Published: January 2021

Abstract

Objective. The use of an electroencephalogram (EEG) anticipation-related component, the expectancy wave (E-wave), in brain–machine interaction was proposed more than 50 years ago. This possibility was not explored for decades, but recently it was shown that voluntary attempts to select items using eye fixations, but not spontaneous eye fixations, are accompanied by the E-wave. Thus, the use of the E-wave detection was proposed for the enhancement of gaze interaction technology, which has a strong need for a mean to decide if a gaze behavior is voluntary or not. Here, we attempted at estimating whether this approach can be used in the context of moving object selection through smooth pursuit eye movements. Approach. Eighteen participants selected, one by one, items which moved on a computer screen, by gazing at them. In separate runs, the participants performed tasks not related to voluntary selection but also provoking smooth pursuit. A low-cost consumer-grade eye tracker was used for item selection. Main results. A component resembling the E-wave was found in the averaged EEG segments time-locked to voluntary selection events of every participant. Linear discriminant analysis with shrinkage regularization classified the intentional and spontaneous smooth pursuit eye movements, using single-trial 300 ms long EEG segments, significantly above chance in eight participants. When the classifier output was averaged over ten subsequent data segments, median group ROC AUC of 0.75 was achieved. Significance. The results suggest the possible usefulness of the E-wave detection in the gaze-based selection of moving items, e.g. in video games. This technique might be more effective when trial data can be averaged, thus it could be considered for use in passive interfaces, for example, in estimating the degree of the user’s involvement during gaze-based interaction.
Multiple-isotope pellet cycles captured by turbulent transport modelling in the JET tokamak
Authors: Marin M. , Citrin J. , Garzotti L. , Valovic M. , Bourdelle C. , Camenen Y. , Casson F.J. , Ho A. , Koechl F. , Maslov M. , JET Contributors  
Published: January 2021

Abstract
For the first time the pellet cycle of a multiple-isotope plasma is successfully reproduced with reduced turbulent transport modelling, within an integrated simulation framework. Future nuclear fusion reactors are likely to be fuelled by cryogenic pellet injection, due to higher penetration and faster response times. Accurate pellet cycle modelling is crucial to assess fuelling efficiency and burn control. In recent Joint European Torus tokamak experiments, deuterium pellets with reactor-relevant deposition characteristics were injected into a pure hydrogen plasma. Measurements of the isotope ratio profile inferred a deuterium penetration time comparable to the energy confinement time. The modelling successfully reproduces the plasma thermodynamic profiles and the fast deuterium penetration timescale. The predictions of the reduced turbulence model QuaLiKiz in the presence of a negative density gradient following pellet deposition are compared with GENE linear and nonlinear higher fidelity modelling. The results are encouraging with regard to reactor fuelling capability and burn control.