bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pemberdayaan Guru Pembina PMR dan Santri Melalui Pelatihan Pertolongan Pertama Pada Kecelakaan (P3K)
Authors: Sujarwadi Mokh. , Zuhroidah Ida , Toha Mukhammad , Huda Nurul 
Published: October 2021

ABSTRAK Pertolongan pertama merupakan perawatan pertama yang diberikan sebelum pertolongan medis datang. Prinsip-prinsip P3K adalah tindakan yang dilakukan segera, mempertahankan hidup korban, mengurangi penderitaan, mencegah pengotoran luka dan penderitaan lanjutan serta merujuk korban ke tempat pelayanan kesehatan terdekat. Palang merah remaja merupakan kegiatan remaja di sekolah dalam bentuk extrakulikuler. Tujuan dari kegiatan pengabdian ini adalah meningkatkan pengetahuan guru Pembina PMR dan santri tentang pelatihan pertolongan pertama pada kecelakaan. Metode yang digunakan adalah ceramah, diskusi serta pelatihan. Terjadi peningkatan pengetahuan sebelum dan sesudah dilakukan pelatihan dengan adanya peningkatan pengetahuan 90% dari hasil pre test. Peserta juga memapu mempraktekkan cara menghentikan perdarahan, pembidaian, perawatan luka serta penanganan gigitan ular. Kata Kunci : pemberdayaan, guru pembina PMR, santri, P3K ABSTRACT First aid is the first treatment given before medical help arrives. The principles of P3K are actions that are taken immediately, maintain the victim's life, reduce suffering, prevent fouling wounds and further suffering and refer the victim to the nearest health service place. The youth red cross is an activity of youth in schools in the form of extracurricular activities. This service activity aims to increase the knowledge of PMR guidance teachers and students about first aid training. The methods used are lectures, discussions, and training. There was an increase in knowledge before and after training with an increase in knowledge of 90% from the pre-test results. The participants also practiced how to stop bleeding, splinting, treating wounds, and handling snake bites. Keywords: empowerment of PMR supervisors, students, first aid
Penerapan Manajemen Terpadu Balita Sakit (MTBS) Pada Kader Posyandu Dan Masyarakat
Authors: Faisal T. Iskandar Iskandar , Khaira Nuswatul , Niswah Niswah , Alchalidi Alchalidi , Dewita Dewita , Veri Nora 
Published: October 2021

ABSTRAK Salah satu langkah dalam pencapaian target Millenium Development Goals/MDG’s (goal ke-4) adalah menurunkan kematian anak menjadi 2/3 bagian dari tahun 1990 sampai pada 2020. Dalam mencapai target tersebut, pemerintah salah satunya menerapkan Majemen Terpadu Balita Sakit (MTBS) yaitu merupakan pendekatan keterpaduan dalam tatalaksana balita sakit yang datang berobat ke fasilitas rawat jalan. Saat ini banyak tenaga kesehatan, kader dan masyarakat yang tidak mengetahui secara menyeluruh tentang penerapan MTBS. Tujuan kegiatan pengabdian dilakukan untuk meningkatkan pengetahuan kader dalam menerapkan MTBS. Metode pelaksanaan adalah dengan pemberdayaan kader dalam penerapan MTBS sehingga dapar dilakukan upara preventif dan kuratif pada balita sakit. Hasil kegiatan menunjukkan kegiatan diikuti oleh 100% sasaran kegiatan dan peserta mampu mengikuti kegiatan sampai akhir. Kata Kunci : Manajemen Terpadu Balita Sakit, Diare, Oralit, Kader Posyandu ABSTRACT One of the steps in achieving the Millennium Development Goals / MDG's target (goal 4) is to reduce child mortality to 2/3 parts from 1990 to 2020. In achieving this target, the government is one of them implementing the Integrated Management of Sick Toddlers (MTBS), which is an integrated approach in management. sick toddlers who come for treatment at outpatient facilities. Currently, many village health workers and the community do not know thoroughly about the implementation of MTBS. The purpose of this service activity is to increase the knowledge of village health workers in implementing MTBS. The method of implementation is by empowering village health workers in the implementation of MTBS so that preventive and curative measures can be carried out for sick toddlers. The results of the activity showed that the activity was followed by 100% of the target of the activity and the participants were able to follow the activity until the end. Keywords: Integrated Management of Sick Toddlers, Diarrhea, ORS, village health worker
Meningkatkan Pengetahuan Diet Garam Pengurang Risiko Hipertensi, Dusun Sidodadi, Kecamatan Penegahan, Lampung Selatan
Authors: Kusumaningsih Dewi , Nismawati Anisa 
Published: October 2021

ABSTRAK Tekanan darah tinggi dapat dipahami sebagai silent killer, sering terlihat tanpa keluhan, sehingga pasien tidak tahu mereka memiliki tekanan darah tinggi dan baru mengetahuinya setelah terjadi komplikasi. Saat ini, terutama ditemukan di negara berkembang. Data dari Global Status of NCDs tahun 2010 menunjukkan bahwa prevalensi hipertensi di Negara berkembang sekitar 40% tambahan di negara maju yang mencapai 35% dari total populasi. Organisasi Kesehatan Dunia mengatakan wilayah Afrika telah mengalami peningkatan prevalensi hingga 46% sementara Amerika telah mencapai 35%. Tujuan setelah penyuluhan adalah untuk menurunkan prevalensi hipertensi pada masyarakat Desa Sidodadi, Kecamatan Penengahan, Lampung Selatan. Operasi dilakukan dalam bentuk tip menggunakan lebar punggung. Peningkatan pengetahuan dan keterampilan yang dialami responden mencapai 60% tentang penurunan risiko hipertensi di Desa Sidodadi, Kecamatan Penengahan, Lampung Selatan. Kata Kunci: Peningkatan, Pengetahuan tentang diet asin, Hipertensi, Keluarga ABSTRACT hypertension is known as a silent killer Often asymptomatic to complain about, so patients Without knowing that they have high blood pressure and do not know until there are complications. Currently, it is mainly found in developing countries. Data from the 2010 Global State of Noncommunicable Diseases report shows that the hypertension rate in developing countries to be about 40% taller than in developed countries, which account for 35% of the total population. The World Health Organization says the Africa region has seen an increase in prevalence to 46 percent while the Americas hit 35 percent. The objective after the consultation was to reduce the rate of hypertension in of community from Sidodadi village, Penengahan district, southern Lampung. The operation is performed in the form of tips using the width of the back. Increased knowledge and skills on hypertension risk reduction in Sidodadi village, Penengahan district, south of Lampung. Keywords: Increase, Knowledge of the salty diet, Hypertension, Family
Hubungan Antara Tekanan Darah Sistolik dengan Kadar Kolesterol Total pada Pasien Diabetes Melitus Tipe 2 di Klinik Arafah Lampung Tengah
Authors: Esfandiari Firhat , Triwahyuni Tusy , Arania Resti , Aysa Najmi Bias 
Published: October 2021

ABSTRACT: RELATIONSHIP BETWEEN SYSTOLIC BLOOD PRESSURE AND TOTAL CHOLESTEROL LEVEL IN TYPE 2 DIABETES MELLITUS PATIENTS IN ARAFAH CLINIC, CENTRAL LAMPUNG Background: Diabetes mellitus type 2 is a disease characterized by hyperglycemia, with the underlying cause being an increase in insulin resistance and or an increase in pancreatic beta cell dysfunction (Decroli, 2019). Diabetes mellitus, hypertension and increased cholesterol levels are conditions that are often found to be interrelated. Hypertension and increased cholesterol levels can be comorbid conditions that accompany DM (Noviyanti et al., 2015). Objective: This study aimed to determine the correlation between systolic blood pressure levels and total cholesterol levels in patients with type 2 diabetes mellitus at the Arafah Clinic, Central Lampung. Method: The type of research used in this research is descriptive analytic with aapproach Cross Sectional. As well as samples taken from Arafah Clinic patients diagnosed with type 2 diabetes, as many as 46 patients. Results: Based on the results of thetest, it was fisher exact found that there was no correlation with the p value = 0.735 (p> 0.05). Conclusion: H0 is received, which means there is no significant correlation between systolic blood pressure and total cholesterol levels in type 2 DM patients at the Arafah Clinic, Central Lampung. Keywords: Systolic Blood Pressure, Total Cholesterol Levels, Type 2 Diabetes Mellitus INTISARI: HUBUNGAN ANTARA TEKANAN DARAH SISTOLIK DENGAN KADAR KOLESTEROL TOTAL PADA PASIEN DIABETES MELITUS TIPE 2 DI KLINIK ARAFAH LAMPUNG TENGAH Latar Belakang: Diabetes Melitus tipe 2 merupakan suatu penyakit dengan karakteristik hiperglikemia, dengan penyebab yang mendasarinya adalah peningkatan resistensi insulin dan atau peningkatan disfungsi sel beta pankreas (Decroli, 2019). Diabetes melitus, hipertensi dan peningkatan kadar kolesterol merupakan keadaan yang sering dijumpai saling berkaitan. Hipertensi dan peningkatan kadar kolesterol bisa menjadi kondisi komorbiditas yang menyertai DM (Noviyanti et al., 2015).Tujuan: Penelitian ini ditujukkan untuk mengetahui hubungn antara kadar tekanan darah sistolik dengan kadar kolesterol total pada pasien diabetes melitus tipe 2 di Klinik Arafah Lampung Tengah.Metodologi: Jenis penelitian yang digunakan pada penelitian ini adalah deskriptif analitik dengan pendekatan Cross Sectional. Serta sampel diambil dari pasien Klinik Arafah yang terdiagnosa DM tipe 2 yaitu sebanyak 46 pasien.Hasil: Berdasarkan dari hasil uji fisher exact didapatkan tidak adanya hubungan dengan nilai p =0,735 (p>0,05).Kesimpulan: Didapatkan H0 yang diterima yang berarti tidak ada hubungan yang signifikan antara tekanan darah sistolik dengan kadar koletesterol total pada pasien DM tipe 2 di Klinik Arafah Lampung Tengah. Kata Kunci:Tekanan Darah Sistolik, Kadar Kolesterol Total, Diabetes Melitus tipe
Estrés Postraumático, Síndrome de la Cabaña, Covid 19 y Psicología Positiva: Caso Práctico
Authors: Chagñay Lema Graciela , Córdova Suárez Manolo Alexander 
Published: October 2021

Introducción. En la pandemia del COVID-19, las personas han experimentado el encierro luego de haber vivido durante mucho tiempo la cuarentena y el teletrabajo se refleja la necesidad urgente de abandonar el domicilio y volver a la realidad pero el miedo al contagio puede más, uno de las consecuencias es el estrés postraumático. Objetivo. La investigación es determinar los niveles de presencia del Síndrome de la Cabaña en los trabajadores del Gad Provincial de Zamora Metodología. Se realizó mediante un estudio transversal aplicado a 373 funcionarios en nómina, se estableció una muestra determinada con el calculador muestral surveymonkey con un valor de 189 trabajadores. Se evaluaron variables sociodemográficas de los trabajadores. Se aplicó el test del Síndrome de la Cabaña para medir los niveles de los trabajadores por confinamiento y Covid 19. Resultados. Los resultados del estudio muestran la presencia de 64 % del síndrome con temor a volver a salir de casa y volver a una nueva realidad. Conclusión. De lo detectado se concluye que uno de los efectos psicológicos es el estrés Postraumático por haber perdido a un amigo, familiar, conocido necesita de primeros auxilios psicológicos ser escuchado o derivado a un especialista. Para disminuir el nivel medio encontrado se recomienda paulatinamente ir saliendo de casa cómo una rutina progresiva de romper este miedo al contagio del virus.
Agresiones protésicas a la mucosa bucal en pacientes geriátricos rehabilitados con prótesis estomatológicas removibles.
Authors: Espasandín González Suleydis , González Díaz Yusmel , Reyes Suárez Vicia Olga , González Casañas Barbara Yushimitt 
Published: October 2021

Las lesiones a la mucosa bucal en los pacientes geritricos constituyen un problema de salud bucal entre los rehabilitados con protesis estomatologicas removibles. Con el objetivo de determinar las formas clínicas agudas y crónicas de las agresiones protésicas a la mucosa bucal, su localización e irregularidad protésica asociada, así como identificar los hábitos protésicos inadecuados y nocivos en estos pacientes se realizó una investigacion observacional,descriptiva y transversal en la Cliníca estomatológica ¨ Andrés Ortíz Junco¨ del municipio Guines ,Mayabeque, en el período de octubre del 2019 a octubre del 2021. El universo 360 pacientes y la muestra 80 seleccionados por un muestreo no probabilístico,intencionado y oportunista.Se formaron dos grupos iguales numéricamente, uno con lesiones agudas y otro con lesiones crónicas. Las variabes en estudio fueron: formas clínicas agudas y crónicas de las agresiones a la mucosa bucal, zonas de localización, irregularidad protésica y hábitos protésicos inadecuados y nocivos. Se realizo un interrogatorio el examen bucal y de las protesis en uso.El análisis estadístico se realizó a través de la docima X2 y Duncan. Como resultados se obtuvieron que el 38,75 % de las lesiones eran estomatitis subprótesis y un 28,75 % úlceras traumáticas. El 37,40 % con afectación del paladar. El 39,02 % de las prótesis tenían como irregularidad protésica la sobre compresión. El 48,75 % de los pacientes usaban la prótesis de forma continua, el 41,25 % con una higiene deficiente y un 53,75 % eran fumadores. De lo que se concluyó que la lesión cronica más frecuente fue la estomatitis subprótesis y de las agudas la úlcera traumatica, el áreas más afectada el paladar.La irregularidad protésica más común fue la sobre compresión. Predominó el uso continuo de la prótesis, la higiene deficiente y el tabaquismo.
Utilization Trends of Antiviral and Antifungal Agents for Human Systemic Use in Tanzania From 2010 to 2017 Using the World Health Organization Collaborating Centre for Drug Statistics Methodology
Authors: Hamim Hafidh , Sangeda Raphael Z. , Bundala Maganga , Mkumbwa Sonia , Bitegeko Adonis , Sillo Hiiti B. , Fimbo Adam M. , Chambuso Mhina , Mbugi Erasto V. 
Published: October 2021

IntroductionThe increase in antimicrobial consumption contributes to the emergence of antimicrobial resistance (AMR). Many studies have investigated the patterns of antibacterial consumption and antibacterial resistance. However, there is a paucity of data on the utilization of antivirals and antifungals in low and middle-income countries to serve as a baseline for monitoring and surveillance of AMR. Therefore, this study determined Tanzania’s systemic antifungal and antiviral utilization trends from 2010 to 2017, based on the Tanzania Medicines and Medical Devices Authority (TMDA) medicine importation archives.MethodologyAn analytical, longitudinal retrospective survey covering 2010 to 2017 was conducted. The study utilized the Anatomical Therapeutic and Chemical (ATC) classification and Defined Daily Dose (DDD) developed by the World Health Organization (WHO) Collaborating Centre for Drug Statistics and the WHO Collaboration Centre for International Drug Consumption Monitoring. Human medicine importation data were collected from TMDA headquarters and used to assess the systemic antiviral and antifungal consumption trends. The importation data included the date, generic name, strength, brand name, currency, quantity, ATC classification, supplier country, port of entry and product supplier. The data were cleaned, reorganized and analyzed. Reference was made to the latest revised DDD list to assign antifungals and antivirals to their respective ATC/DDDs and then adjusted to the population estimates from the National Bureau of Statistics of Tanzania.ResultsThere was a high proportion of systemic antivirals and antifungals utilization with 367.1 and 10.8 DDD per 1000 inhabitants per day (DID) respectively over eight years. In regression model, there was a significant increase in both antiviral (p-value = 0.043) and antifungal (p-value = 0.015) agents’ utilization trends in Tanzania in the study period. Fluconazole had the highest proportion of utilization for antifungals, followed by ketoconazole, itraconazole, miconazole and amphotericin B. For systemic antivirals, a high proportion was attributed to antiretrovirals used for HIV infections.ConclusionFindings from this study suggest an increase in the utilization of systemic antiviral and antifungal agents. These findings may be used to further benchmark utilization and AMR studies in Tanzania.
Folic Acid Alleviates High Glucose and Fat-Induced Pyroptosis via Inhibition of the Hippo Signal Pathway on H9C2 Cells
Authors: Hong Lei , Zha Yingjie , Wang Chen , Qiao Shigang , An Jianzhong 
Published: October 2021

Diabetic cardiomyopathy (DCM) is the leading cause of death in diabetic patients. Folic acid has a protective effect on diabetes-induced cardiomyocyte damage. The aim of this study was to explore the effects of folic acid on cardiomyocytes cultured under high glucose and fat (HGF) conditions and type 2 diabetes mellitus (T2DM) mice, and elucidate the underlying mechanisms. Bioinformatics analysis was used to identify the potential drugs through the Drug-Gene Interaction database. H9C2 cardiomyocytes were cultured with 30 mM glucose and 500 nM palmitic acid in the presence or absence of folic acid or YAP1 inhibitor (verteporfin) or YAP1 siRNA. The cell viability and lactate dehydrogenase (LDH) release were measured using specific assay kits. Pyroptosis was detected by flow cytometry. The concentrations of IL-1β and IL-18 in the supernatants were measured by ELISA. The NLRP3, ASC and caspase-1 mRNA levels were detected by qRT-PCR and that the proteins expression of NLRP3, ASC, cleaved caspase-1 (p10), caspase-1, YAP1, p-YAP1, LATS1 and P-LATS1 were detected by Western blotting. C57BL/6 mice were fed with high fat diet (HFD) combined with streptozotocin (STZ) intraperitoneally to establish a T2DM model, folic acid or PBS treatment for 8 weeks by oral gavage, blood glucose and body weight were measured every 4 weeks, mouse heart tissue was used to detect pyroptosis and hippo signaling pathway related protein expression. We identified 427 differentially expressed genes in the cardiac tissues of high fat diet + streptozotocin mice, among the 30 most significantly DEGs, folic acid was predicted to be the most likely therapeutic drug. Folic acid alleviated HGF-induced cell damage in vitro and in vivo by decreasing activation of the Hippo pathway, as indicated by lower LDH release and increased cell viability, and decreased expression of NLRP3, ASC, cleaved caspase-1, IL-1β, IL-18, p-YAP and p-LATS. Verteporfin or YAP1 siRNA neutralized the protective effect of folic acid by reversing YAP1-induced pyroptosis. Folic acid reduced NLRP3 inflammasome-mediated pyroptosis by down-regulating the Hippo signaling pathway, thereby effectively reducing T2DM-induced damage in H9C2 cells and animals.
Clinical Assessment of Visual Motion Perception in Children With Brain Damage: A Comparison With Base Rates and Control Sample
Authors: van der Zee Ymie J. , Stiers Peter L. J. , Lagae Lieven , Evenhuis Heleen M. 
Published: October 2021

Aim: In this study, we examined (1) the presence of abnormally low scores (below 10th percentile) in various visual motion perception aspects in children with brain damage, while controlling for their cognitive developmental delay; (2) whether the risk is increased in comparison with the observation and expectation in a healthy control group and healthy population.Methods: Performance levels of 46 children with indications of brain damage (Mage = 7y4m, SD = 2y4m) on three visual motion perception aspects (global motion, motion speed, motion-defined form) were evaluated. We used developmental age as entry of a preliminary reference table to classify the patient’s performance levels. Then we compared the percentages of abnormally low scores with percentages expected in the healthy population using estimated base rates and the observed percentages in the control sample (n = 119).Results: When using developmental age as reference level, the percentage of low scores on at least one of the three tasks was significantly higher than expected in the healthy population [19/46, 41% (95%CI: 28–56%), p = 0.03]. In 15/19 (79% [95%CI: 61–97%] patients only one aspect of motion perception was affected. Four patients performed abnormally low on two out of three tasks, which is also higher than expected (4/46, 8.7%, 95%CI: 2.4–20.8% vs. 2.1%; z = 2.61, p &lt; 0.01). The observed percentages in the patient group were also higher than found in the control group.Interpretation: There is some evidence that children with early brain damage have an increased risk of isolated and combined motion perception problems, independent of their performance IQ.
Comparison of Biochemical and Pathological Parameters and Parenteral Nutrition of ICU Patients Under Supervision of Dietitians and Surgeons
Authors: Behrad Nasab Mojgan , Akbari Mohammad Esmail , Rastgoo Samira , Gholami Somayeh , Hajipour Azadeh , Majidi Nazanin , Gholamalizadeh Maryam , Mirzaei Dahka Samaneh , Doaei Saied , Goodarzi Mark O. 
Published: October 2021

Background: Nutrient imbalance can frequently occur in patients with indications for parenteral nutrition (PN) after gastrointestinal surgery. This study aimed to compare the recommendations of a surgeon to those of a dietitian in the field of parenteral nutrition.Methods: This study was performed on 256 patients undergoing gastrointestinal surgery who received PN, which included 120 patients who received PN based on recommendations of the surgeons and 136 patients who were referred to receive PN under the supervision of a dietitian in Razi Hospital in Rasht, Iran. Data on PN and clinical outcomes of the patients were collected.Results: Patients under the supervision of dietitians received higher vitamin B complex and lipids and lower vitamin A and vitamin E than the surgeon-supervised patients (all P &lt; 0.001). In the group receiving PN under the supervision of a surgeon, the level of blood glucose (207 vs. 182, P &lt; 0.01), sodium (138 vs. 136, P = 0.01), potassium (3.97 vs. 3.53, P &lt; 0.01), and white blood cell count (9.83 vs. 9.28, P &lt; 0.01) increased significantly at the end of the PN compared to baseline. In the group receiving PN under the supervision of a dietician, the level of serum Cr (1.23 vs. 1.32, P = 0.04), Mg (2.07 vs. 1.84, P &lt; 0.01), and pH (7.45 vs. 7.5, P = 0.03) significantly improved after receiving parenteral nutrition compared to baseline.Conclusion: The amounts of nutrients recommended for PN by the surgeon and dietitian were different. Implementation of dietitian recommendations in critically ill patients under PN can improve patients' clinical parameters.