bluuebunny/crossref_metadata_2025_split huggingface dataset:
INTERNATIONAL RESEARCH COOPERATION IS EFFECTIVE MECHANISM FOR FORENSIC SCIENCE IMPROVEMENT
Authors: Kliuiev O. 
Published: October 2021

The article reveals the content of international research cooperation of science forensic institutions of Ukraine other countries across the world. One of the main areas of work of forensic science institutions of Ukraine is compliance with European standards for forensic examinations and forensic researches. Because of this current trend at the present stage is to expand participation of forensic science institutions in international cooperation, increase their role in the further development of theory and practice of forensic science and criminalistics. It is concluded that improvement of forensic activity in Ukraine and international cooperation in the field of expert support of justice is one of the leading activities of National Scientific Center «Hon. Prof. M. S. Bokarius Forensic Science Institute» of the Ministry of Justice of Ukraine.
The international agreements/memoranda with the partner institutions of NSC « Hon. Prof. M. S. Bokarius FSI» are indicated, in which provisions the main strategic directions of research cooperation in the field of forensic science and criminalistics are determined. It is concluded that in-depth research of problematic aspects of forensic practice, use of the latest and most advanced technology in conducting forensic examinations and forensic researches is the guarantee for to improving efficiency of forensic science institutions of Ukraine and in the near future will open new horizons for forensic science and criminalistics.
Telaah Konsep Arsitektur Rustic Pada Bangunan Restoran Foodsmith Firewood Oven & Grill
Authors: Ghifari Farrel , Purwantiasning Ari Widyati 
Published: October 2021

Arsitektur rustic merupakan konsep arsitektur yang menitikberatkan pada kesan alami dan menghasilkan suasana yang hangat pada penerapan konsepnya. Arsitektur rustic memiliki prinsip-prinsip dasar yang dapat dijadikan sebagai rujukan dalam merancang bangungn konsep arsitektur rustic, yaitu penggunan material kayu yang dominan, unfinished pada bagian dinding, penggunaan material yang memanfaatkan sumber daya alam seperti kayu, batu dan logam, menggunakan warna natural pada bagian elemen pembentuk ruang yaitu lantai, dinding dan plafond, terakhir yaitu penggunaan material berkesan tua. Arsitektur rustic dapat menambah daya tarik bangunan restoran sehingga menjadikan suasana restoran menjadi hangat dan alami. Penelitian ini menggunakan metode deskritif kualitatif untuk mengetahui tentang penerapan arsitektur rustic pada restoran. Analisis dilakukan secara deskritif kualitatif dengan menggunakan prinsip-prinsip arsitektur rustic. Tujuan peneltian ini yaitu bertujuan untuk mengetahui dan memahami prinsip-prinsip arsitektur rustic dan penerapannya pada bangunan restoran. Kesimpulan yang akan diperoleh dari penelitian ini yaitu bahwa konsep arsitektur rustic dapat diterapkan pada restoran dengan menerapkan prinsip-prinsip arsitektur rustic sehingga menjadikan suasana restoran menjadi hangat dan alami bahkan dapat menjadi ikonik, unik dan instagramable.
Optimalisasi Ruang Terbuka Hijau Publik Yang Ramah Disabilitas Di Benteng Kuto Besak Palembang
Authors: Sary Reny Kartika , Jaya Meldo Andi 
Published: October 2021

Salahsatu elemen kota yang terpenting yang menyangkut keberlangsungan hidup suatu kota diantaranya adalah ketersediaan untuk Ruang Terbuka Hijau Publik. Fasilitas publik ini harus mudah diakses secara bersama-sama dan aman digunakan serta manfaatnya dapat dinikmati oleh seluruh orang baik yang fisiknya normal maupun dengan masalah disabilitas. Penelitian ini secara umum untuk meneliti serta mendesain Ruang Terbuka Hijau Publik yang berada dikota Palembang yang ramah dan juga bisa dinikmati manfaatnya oleh semua orang termasuk dengan masalah disabilitas. Adapun penelitian ini akan dititik beratkan di Benteng Kuto Besak(BKB) dimana fasilitas ini merupakan fasilitas publik yang paling digemari oleh masyarakat Kota Palembang. Sedangkan tujuan khusus penelitian ini adalah mendesain ulang RTH publik yang sudah dilakukan sehingga bisa mendapatkan satu desain yang baik, efektif dan tepat guna bagi masyarakat khususnya penyandang disabilitas. Penelitian ini akan dilakukan dengan menggunakan metode survey yang bertujuan untuk menggambarkan situasi yang terjadi pada kawasan Benteng Kuto Besak dengan melakukan pengamatan dan pengukuran terhadap objek dan fungsi fasilitas yang ada. Kemudian di analisis dengan literature yang ada, kemudian di dilakukan evaluasi terhadap fasilitas penunjang kaum disabilitas yang terdapat pada Ruang Terbuka di BKB. Hasil akhir yang akan didapatkan adalah desain ruang terbuka yang ramah, aman dan informatif bagi penyandang disabilitas sehingga bisa meningkatkan kualitas hidup dan lingkungan yang sehat, indah, nyaman dan aman. Luaran penelitian ini adalah: (1) RTH Publik yang sesuai dengan standar Peraturan Menteri Pekerjaan Umum No 5/PRT/M/2008; (2) RTH Publik yang ramah terhadap penyandang disabilitas yang sesuai dengan Peraturan Menteri PUPR No. 14 Tahun 2017
The Effect of Using Different Levels of Thinner Olive Oil (Extra Virgin Olive Oil) on the Viability and Abnormality of Spermatozoa and pH of the Semen Duroc Pigs
Authors: Nahak Stefanus , Dethan Agustinus Agung , Tahuk Paulus Klau 
Published: October 2021

This study aims to determine the effect of using different levels of thinner olive oil (extra virgin olive oil) on the viability and abnormality of spermatozoa and the pH of the semen of duroc pigs. The research took place in September 2020 in Noenebu, Tapenpah Village, Insana District, North Central Timor Regency, and the Laboratory of the Faculty of Agriculture, University of Timor. This study used a completely randomized design (CRD) with 4 treatments and 5 replications. Treatment R1 consist of 10% tris solution, 10% olive oil, 80% semen; R2 treatment consist of 15% tris solution, 15% olive oil, 70% semen; R3 treatment consist of 20% tris solution, 20% olive oil, 60% semen, and R4 treatment consist of 25% tris solution, 25% olive oil, 50% semen. The results showed that the effect of different treatments was very significant (P <0.01) on the viability of spermatozoa. The mean spermatozoa viability of each treatment was R1 of 89 ± 2.57%, R2 of 76.9 ± 12.51%, R3 of 62.8 ± 3.11%, and R4 treatment of 41.2 ± 15, 38%. The spermatozoa abnormalities were significantly different (P <0.05). Where the abnormality of the spermatozoa in treatment R1 was 8.8 ± 1.30%, R2 was 10.4 ± 1.67%, R3 was 11.6 ± 1.81%, and R4 was 14.4 ± 3.78%. The degree of acidity (pH) of the semen was not significantly different between treatments. The pH value of each treatment was R1 of 7.92 ± 0.83, R2 of 8.04 ± 0.54, R3 of 7.96 ± 0.39; and R4 treatment of 8.06 ± 0.64. It can be concluded that the addition of 10% to 20% olive oil can maintain the viability and abnormality of duroc boar male spermatozoa. However, the use of olive oil up to 20% does not affect to degree of acidity of the semen produced.
Performance Analysis and Added Value of Industry Processing Beef into Processed Meat Jengken and Shredded in the Kota Kefamenanu District
Authors: LAU VICTORIA SARI , Sio Stefanus , Purwatiningsih Theresia Ika , Sikone Hilarius Y. 
Published: October 2021

This research aims to determine the performance of the beef processing industry in Kefamenanu City District and to analyze the amount of added value generated from beef processing in Kefamenanu City District. This research was conducted in the MSMEs VIVI meat processing industry, Kefamenanu City District, North Central Timor Regency. This study used the Surfei method with quantitative descriptive analysis. The variables observed were the performance of the meat processing industry and the added value of beef processing. The application of the balanced scorecard concept in analyzing the performance of VIVI MSMEs shows that from a financial perspective it has a good performance with an infinite CR value; average NPM 8,216%; an average ROA of 15,39% and an average ROI of 2,24 times of the investment value. From the customer perspective, it has a good performance with 51,49% of general customers who are satisfied and 49,79% of partner customers who are satisfied. For the perspective of internal business processes and the perspective of learning and growth have a good performance, respectively, with a value of 60,76% and 54,86%, respectively. It is concluded that the value added of beef products per kilogram of output is Rp. 48.060.00 for shredded products and beef jerky products of Rp. 37.551.00.
Rounding Harmony in Mfantse: Evidence and Differences
Authors: Obeng Patience , Ollennu Yvonne A.A. 
Published: October 2021

This paper investigated rounding harmony in two subdialects of Mfantse spoken in the Central Region of Ghana. Bɔrbɔr and Edwumako dialects are part of the Akan language and belongs to Kwa on the Niger-Congo branch of languages. Data was from the Mfantseman and Edwumako districts from 45 participants aged 20 years and above. The Autosegmental framework was used for data analysis. We looked first at the sounds and brought out the differences between Bɔrbɔr sounds and that of Edwumako. The study established that Mfantse is not the same in all its phonological presentations in all its subdialects. In terms of sound distribution, the central unadvanced vowel is strictly word final in Bɔrbɔr while it is both word initial and final in Edwumako. Some aspects of rounding harmony occur in both Bɔrbɔr and Edwumako while other aspects occur in Bɔrbɔr and partially in Edwumako. Other aspects are present in Edwumako only.
Nora's Transcendental Consciousness from Marianne's Sensibility: A Reading of Ibsen's A Doll's House and Austen's Sense and Sensibility
Authors: Sultana Tanzin , Nower Durdana 
Published: October 2021

This paper attempts to bring out the nineteenth century's women’s quest for self-respect and self-actuality in the mirror of Nora’s developing consciousness following Marianne’s growing sensibility. Jane Austen’s Sense and Sensibility, and Henrik Ibsen’s A Doll’s House are two prominent genres of ninetieth century’s English literature where both writers show the contemporary women’s soul being entangled to social norms as well as their gradual try to be non-conformist against these norms by their thought and action. In the 19th century, English society creates impediments for unmarried women like Marianne and married women like Nora to think and to talk in their way. It is the patriarchal society where women’s social dignity and security depend on their marital status and husbands. Since marriage is their identity, they show their loyalty and sincerity to their husbands or the men they love. In Austen’s novel, as an ordinary woman, Marianne takes Willoughby’s attention as a scared bonding and challenges the seniors’ matured advice. In Ibsen’s play, Nora does forgery and secretly takes a loan to save her sick husband’s life. She considers it a spouse’s duty and believes that her husband will understand her as he cares for her. When the time comes, both Marianne and Nora betray their loyalty from their partners to whom they are not human beings but puppets to be entertained. From this violation of trust, they realize that they need to be considered human beings first before being respected women in a family and society. It is their strength that despite being taken as soulless creatures, they dare to think about own self beyond the society and become self-reliant. Their growing self-reliance makes today’s women progressive in creating a space in society and family for themselves as human beings.
Análisis informático forense a vehículos aéreos no tripulados (dron)
Authors: Guerrero Montero Carlos Alberto , Pazmiño Gómez Luis Alberto 
Published: October 2021

Introducción. La presente investigación surge de la necesidad de saber qué información puede almacenar un vehículo no tripulado (dron), ya que, muchas veces se utilizan como medio de diversión, para hacer competencias y acrobacias, pero fundamentalmente, se emplean para espiar a personas u organizaciones con el objetivo de exponer datos sensibles que las pueden afectar. Objetivo. Realizar un análisis forense para la gestión de la información relacionada a los vehículos no tripulados en el rastreo de las actividades. Metodología. En esta investigación se utilizó un método experimental a partir de una investigación descriptiva-explicativa. De esta manera, se obtiene información forense sobre vehículos no tripulados para la toma de decisiones proactivas. Resultados. Se pudo localizar los archivos multimedia grabados. Las fotos y los vídeos se exportaron para su posterior análisis. Los datos EXIF (archivo de imagen intercambiable) son información incrustada dentro de imágenes JPEG. Los datos EXIF obtenidos fueron: Fecha, Marca de tiempo, Fuente de archivo, GPS, Altitud, Referencia de altitud, Latitud, Longitud. Esta información ayudara a determinar dónde y cuándo se tomaron las fotos. Conclusión. La metodología aplicada es de gran utilidad siempre y cuando el dron cuente con una memoria de almacenamiento extraíble además se puede complementar la aplicación de esta metodología teniendo acceso a los dispositivos de radio control ya sean mandos inalámbricos, dispositivos inteligentes o computadoras puesto que en estos dispositivos también se almacenan logs, aplicando metodologías específicas de acuerdo con el dispositivo obtenido.
Study on Palmar Dermatoglyphics and their Association with β Thalassemia Major Patients among Bangladeshi Population
Authors: Zahan Afroj , Naushaba Humaira , Paul Uttam Kumar , Islam AHM Mazharul , Moin Sharna , Begum Arifa 
Published: October 2021

Objectives: To observe the palmar dermatoglyphic patterns of β thalassemia major patients.
Methods: This cross-sectional type of analytical study was performed in the Department of Anatomy, Sir Sallimullah Medical College, Dhaka between the periods of January 2016 to December 2016. 55 β thalassemia major patients aged between (5-35) years were considered as case group and 55 healthy individuals of the same age & sex were considered as control group in this study. The palmar dermatoglyphic patterns and Total Finger Ridge count (TFRC) on the distal phalanges of the β thalassemia major patients were observed and compared with healthy individuals.
Results: The palmar dermatoglyphic patterns were significantly different between the two groups (p > 0.05). The mean (±SD) of Total Finger Ridge count (TFRC) were higher in β thalassemia major patients in comparison to the healthy individuals.
Conclusion: This study concludes that, palmar dermatoglyphic has a diagnostic value for β thalassemia major patients.
Mediscope 2021;8(2): 94-102
From Continent to Ocean: Investigating the Multi-Element and Precious Metal Geochemistry of the Paraná-Etendeka Large Igneous Province Using Machine Learning Tools
Authors: Lindsay J. J. , Hughes H. S. R. , Yeomans C. M. , Andersen J. C. Ø. , McDonald I. 
Published: October 2021

Large Igneous Provinces, and by extension the mantle plumes that generate them, are frequently associated with platinum-group element (PGE) ore deposits, yet the processes controlling the metal budget in plume-derived magmas remains debated. In this paper, we present a new whole-rock geochemical data set from the 135 Ma Paraná-Etendeka Large Igneous Province (PELIP) in the South Atlantic, which includes major and trace elements, PGE, and Au concentrations for onshore and offshore lavas from different developmental stages in the province, which underwent significant syn-magmatic continental rifting from 134 Ma onwards. The PELIP presents an opportunity to observe magma geochemistry as the continent and sub-continental lithospheric mantle (SCLM) are progressively removed from a melting environment. Here, we use an unsupervised machine learning approach (featuring the PCA, t-SNE and
k-
means clustering algorithms) to investigate the geochemistry of a set of (primarily basaltic) onshore and offshore PELIP lavas. We test the hypothesis that plume-derived magmas can scavenge precious metals including PGE from the SCLM and explore how metal concentrations might change the metal content in intraplate magmas throughout rifting. Onshore lavas on the Etendeka side of the PELIP are classified as the products of deep partial melts of the mantle below the African craton but without significant PGE enrichment. Offshore lavas on both continents exhibit similarities through the multi-element space to their onshore equivalents, but they again lack PGE enrichment. Of the four onshore lava types on the Paraná side of the PELIP, the Type 1 (Southern) and Type 1 (Central-Northern) localities exhibit separate PGE-enriched assemblages (Ir-Ru-Rh and Pd-Au-Cu, respectively). It follows that there is a significant asymmetry to the metallogenic character of the PELIP, with enrichment focused specifically on lavas from the South American continent edge in Paraná. This asymmetry contrasts with the North Atlantic Igneous Province (NAIP), a similar geodynamic environment in which continent-edge lavas are also PGE-enriched, albeit on both sides of the plume-rift system. We conclude that, given the similarities in PGE studies of plume-rift environments, SCLM incorporation under progressively shallowing (i.e., rifting) asthenospheric conditions promotes the acquisition of metasomatic and residual PGE-bearing minerals, boosting the magma metal budget.
Treadmill Exercise Attenuates Cerebral Ischemia–Reperfusion Injury by Promoting Activation of M2 Microglia via Upregulation of Interleukin-4
Authors: Lu Juanjuan , Wang Jie , Yu Long , Cui Rong , Zhang Ying , Ding Hanqing , Yan Guofeng 
Published: October 2021

Background: Exercise has been proven to be an effective therapy for stroke by reducing the microglia-initiated proinflammatory response. Few studies, however, have focused on the phenotypic changes in microglia cells caused by exercise training. The present study was designed to evaluate the influence of treadmill exercise on microglia polarization and the molecular mechanisms involved.Methods: Male Sprague-Dawley rats were randomly assigned into 3 groups: sham, MCAO and exercise. The middle cerebral artery occlusion (MCAO) and exercise groups received MCAO surgery and the sham group a sham operation. The exercise group also underwent treadmill exercise after the surgery. These groups were studied after 4 and 7 days to evaluate behavioral performance using a modified neurological severity score (mNSS), and infarct conditions using 2,3,5-triphenyl tetrazolium chloride. Quantitative real-time polymerase chain reaction (qRT-PCR) and Luminex was employed to determine the expressions of markers of microglia phenotypes. Western blotting was employed to identify the phosphorylation levels of Janus kinase1 (JAK1) and signal transducer and activator of transcription 6 (STAT6). Immunofluorescence was conducted to identify microglia phenotypes.Results: Treadmill exercise was found to improve neurobehavioral outcomes, mainly motor and balance functions, reduce infarct volumes and significantly increase interleukin-4 (IL-4) expression. In addition, treadmill exercise inhibited M1 microglia and promoted M2 microglia activation as evidenced by decreased M1 and increased M2 markers. Furthermore, an obvious increase in p-JAK1 and p-STAT6 was observed in the exercise group.Conclusions: Treadmill exercise ameliorates cerebral ischemia–reperfusion injury by enhancing IL-4 expression to promote M2 microglia polarization, possibly via the JAK1-STAT6 pathway.
Targeting Long Non-Coding RNA TTN-AS1 Suppresses Bladder Cancer Progression
Authors: Xiao Huiyuan , Huang Wen , Li Yanlei , Zhang Rongxin , Yang Long 
Published: October 2021

Background: To explore the biological and clinical effects of titin-antisense RNA1 (TTN-AS1) in bladder cancer (BC) and the association between TTN-AS1 and activating transcription factor 2 (ATF2) in BC.Methods: The Kaplan–Meier method was performed to analyze the association between the expression of TTN-AS1 and prognosis of BC patients from TCGA data set and our institution. Quantitative real-time PCR (RT-PCR) was conducted to explore the expression of TTN-AS1 between the patients who underwent TURBT and Re-TURBT. MTT, colony formation, and tumor formation assays were conducted to evaluate the effect of TTN-AS1 on the ability of proliferation in BC cell lines. Transwell assay was performed to evaluate the effect of TTN-AS1 on the ability of invasion in BC cell lines. Bioinfomatics and immunohistochemical staining was used to identify the relationship between TTN-AS1 and ATF2.Results: The higher expression of TTN-AS1 was related to poorer disease-free survival (DFS) in patients with BC. The expression of TTN-AS1 was higher in BC patients who underwent Re-TURBT compared with BC patients who underwent TURBT. Knocking down TTN-AS1 resulted in inhibiting the ability of proliferation and invasion of BC cells. ATF2 may serve as a downstream target of TTN-AS1 in BC, and the high expression of ATF2 is also related to adverse DFS.Conclusion: Our study reveals that TTN-AS1 serves as an oncogene by activating ATF2 in BC. The findings suggest that TTN-AS1 may act as a novel therapeutic target for patients with BC.
Integrated Proteotranscriptomics of Human Myometrium in Labor Landscape Reveals the Increased Molecular Associated With Inflammation Under Hypoxia Stress
Authors: Chen Lina , Wang Lele , Luo Yihong , Huang Qian , Ji Kaiyuan , Bao Junjie , Liu Huishu 
Published: October 2021

During labor, a variety of coordinated physiological and biochemical events cause the myometrium to transition from a quiescent to contractile state; the molecular mechanisms responsible for this transition, however, remain unclear. To better understand this transition at a molecular level, the global transcriptome and proteome of human myometrial samples in labor and those not in labor were investigated through RNA sequencing (RNA-seq) and quantitative liquid chromatography–tandem mass spectrometry (LC-MS/MS) via data-independent acquisition (DIA) and parallel reaction monitoring (PRM) methods. Furthermore, an integrated proteotranscriptomic analysis was performed to explore biological processes and pathway alterations during labor; this analysis identified 1,626 differentially expressed mRNAs (1,101 upregulated, 525 downregulated) and 135 differentially expressed proteins (97 upregulated, 38 downregulated) in myometrium between nonlabor and in labor groups. The comprehensive results of these analyses showed that the upregulated mRNAs and proteins increased inflammation under hypoxia stress in the myometrium under labor, and related proteins and cytokines were validated by PRM and Luminex assays. Our study confirmed the biological process of inflammation and hypoxia in laboring myometrium at the transcriptome and proteome levels and provided recourse to discover new molecular and biological changes during labor.