bluuebunny/crossref_metadata_2025_split huggingface dataset:
The treatment dynamics assessment among patients with chronic viral hepatitis B, infected with human immunodeficiency virus
Authors: Moroz L. V. , Melnyk T. O. 
Published: June 2021

Introduction: the article represents prospective study results of the treatment dynamics among patients with chronic viral hepatitis B, infected with human immunodeficiency virus. Particularly, the role of qHBsAg dynamics in the serum concerning CHB treatment effectiveness of CHB/HIV coinfected patients as well as clinical and laboratory factors influencing on this marker.The study purpose: To assess treatment dynamics of CHB/HIV coinfected patients basing on quantitative HBsAg determination and other clinical and laboratory test applying. Material and methods: 60 coinfected patients were examined – the main group, 60 CHB monoinfected patients – comparison group to reach established study purpose. Diagnosis of HIV and chronic hepatitis B were verified. A clinical, laboratory, serological, molecular-genetic methods were used. Statistical processing of results was held with applying parametric and nonparametric methods for the data analysis.Research results: There was a slight increase by 1.10 times in serum ALT in “a period of ≤ 6 months of antiviral therapy” with a subsequent decrease by 1.20-1.46 times in “a period of ˃ 6 months of therapy”. There was a decrease in the serum qHBsAg of coinfected patients in accordance with the duration of therapy by 1.56-21.10 times, and in case of the presence of "ALT flare" by 1.31-72.72 times. The greatest decrease in serum qHBsAg by 1.63-42.00 times during HAART was also observed in patients with an initial CD4 + count <350 cells / μl. A serum qHBsAg was 11.24 times lower after ˃ 12 months of therapy in the group of CHB/HIV coinfected patients with ΔCD4 + ˃100 cells / μl compared with the group of patients with ΔCD4 + 0 - 100 cells / μl.Conclusions: A serum qHBsAg possibly to be decreased by 2 log10 among CHB/HIV coinfected patients after starting HAART with dual activity against HBV and HIV which includes nucleoside reverse transcriptase analogs (Tenofovir Disoproxil Fumarate (TDF) and lamivudine (3TC)). Defined main influencing factors on qHBsAg decreasing included: “ALT flare”, CD4+ count, ΔCD4+ as a result of monofactorial analysis. It is necessary to conduct further multifactorial analysis to determine complex of factors which could influence on further HBsAg by 2 log10 and HBsAg clearance.
Stretching and injuries in men undertaking running training
Authors: Piekorz Zuzanna , Kwiatkowski Damian , Lewandowski Andrzej 
Published: June 2021

Introduction. Physical activity appears in men’s life from the very beginning of their existence, however over last few decades it has become more popular as an amateur sport and recreation. One of the simplest form of physical activity considered as sport is running. Runners very often begin workouts thinking about improving their health but it comes with a risk of getting injured. There are however a lot of factors which can prevent injuries to occur. One of them is doing stretching exercises. The purpose of the study is to validate if stretching exercises can lower the risk of suffering an injury by men beginning a running workouts. In this study it was assumed that doing additional stretching exercises lowers the risk of suffering an injury and is common in people training long-distance running. Materials and Methods.182 men who do running workouts in the city of Bydgoszcz were examined with the use of author’s original questionnaire. It concerned sociodemographic data, running-related issues, stretching and the aspects of sports injuries. Statistics. Ordinal scales were analyzed with nonparametric rank tests, such as the Mann-Withney test, while the nominal scales were tested with nonparametric tests from the Pearson's chi-squared test group. Results. It was found that the largest group of runners are men aged about 32 years, doing running workouts as a part of amateur sport. Of all the subjects, 31% of runners declared the use of additional stretching training. People running with greater frequency and volume, expressed in kilometers, more often decide to undertake stretching exercises. 70% of tested athletes suffered a running-related injury. There was no significant effect of stretching on reducing the risk of injury to runners. Conclusions. Stretching is not very popular among running enthusiasts. Greater running experience and high training loads are factors that make runners decide to use additional stretching exercises more often. The lack of significant differences in the frequency of injuries of competitors using and not undertaking stretching does not allow an unequivocal assessment of its impact on reducing the risk of injury in runners.
Transverse mode locking of different frequency-degenerate families based on annular beam pumping
Authors: Zhang Shunqin , Fu Zenan , Lai Linquan , Jia Fuqiang , Qiao Dun , Fan Yuanlong , Li Kang , Copner Nigel 
Published: June 2021

Optical vortex arrays have been achieved in an end-pumped

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laser pumped by an annular beam. Spontaneous transverse mode locking of Laguerre–Gaussian modes in different frequency-degenerate families has been obtained by merely adjusting the pump power. A maximum output power of 0.88 W and optical conversion efficiency of 13.6% are achieved for optical vortex arrays. Optical vortex arrays formed in different frequency-degenerate families of Laguerre–Gaussian modes can be actively controlled by the position of the axicon. This work provides a way to research transverse mode locking of Laguerre–Gaussian modes in different frequency-degenerate families based on annular beam pumping.
Comprehensive analysis of lncRNA biomarkers in kidney renal clear cell carcinoma by lncRNA-mediated ceRNA network
Authors: Gong Ke , Xie Ting , Luo Yong , Guo Hui , Chen Jinlan , Tan Zhiping , Yang Yifeng , Xie Li 
Published: June 2021

IntroductionKidney renal clear cell carcinoma (KIRC) has a high incidence globally, and its pathogenesis remains unclear. Long non-coding RNA (lncRNA), as a molecular sponge, participates in the regulation of competitive endogenous RNA (ceRNA). We aimed to construct a ceRNA network and screened out possible lncRNAs to predict KIRC prognosis.Material and methodsAll KIRC data were downloaded from the TCGA database and screened to find the possible target lncRNA; a ceRNA network was designed. Next, GO functional enrichment and KEGG pathway of differentially expressed mRNA related to lncRNA were performed. We used Kaplan-Meier curve analysis to predict the survival of these RNAs. We used Cox regression analysis to construct a model to predict KIRC prognosis.ResultsIn the KIRC datasets, 1457 lncRNA, 54 miRNA and 2307 mRNA were screened out. The constructed ceRNA network contained 81 lncRNAs, nine miRNAs, and 17 mRNAs differentially expressed in KIRC. Survival analysis of all differentially expressed RNAs showed that 21 lncRNAs, four miRNAs, and two mRNAs were related to the overall survival rate. Cox regression analysis was performed again, and we found that eight lncRNAs were related to prognosis and used to construct predictive models. Three lnRNAs from independent samples were meaningful.ConclusionThe construction of ceRNA network was involved in the process and transfer of KIRC, and three lncRNAs may be potential targets for predicting KIRC prognosis.
Anxiety and associated factors among Ethiopian health professionals at early stage of COVID-19 pandemic in Ethiopia
Authors: Dagne Henok , Atnafu Asmamaw , Alemu Kassahun , Azale Telake , Yitayih Sewbesew , Dagnew Baye , Maru Alemayehu Abiy , Andualem Zewudu , Mequanent Sisay Malede , Tadesse Demewoz , Hailu Chekol Soliyana , Mengistu Mamo Eyerusalem , Simegn Wudneh 
Published: June 2021

Introduction
In late 2019, a new coronavirus disease known as COVID-19 (novel coronavirus disease 2019) was identified. As there is no any drug to treat this pandemic, the healthcare professionals are disproportionately at higher risk. The mental health outcome is expected to be high. Anxiety is expected to have a significant impact on health professionals, especially among those who work without adequate resources for self-protection.

Objectives
The objectives of this research was to assess self-reported anxiety symptoms and associated factors among Ethiopian healthcare professionals in the early stages of the pandemic.

Methods
We have conducted an online cross-sectional study to collect information from healthcare professionals in Ethiopia during the early stage of the outbreak from April 7, 2020 to May 19, 2020. GAD-7 was used for measurement of anxiety. We have used a cut of point of 10 and above to report anxiety symptoms. We have used Google Forms for online data collection and SPSS-22 for analysis. To determine associated factors for anxiety, a binary logistic regression model was used. Variables with p-value < 0.2 during the bivariable binary logistic regression were exported for further analysis in the multivariable binary logistic regression. Finally, variables with p-value <0.05 were considered as significantly associated with the outcomes.

Results
Three hundred and eighty-eight healthcare professionals filled the online questionnaire; Majority (71.1%) were males. Significant number of respondents (78.9%) reported lack of adequate personal protective equipment (PPE) at the work place. The prevalence of anxiety was 26.8%.
Being female (AOR: 1.88; 95% C.I:1.11, 3.19), visiting/treating 30–150 patients per day (AOR: 3.44; 95% C.I:1.51, 7.84), those employed at private healthcare institutions (AOR: 2.40; 95% C.I:1.17, 4.90), who do not believe that COVID-19 is preventable (AOR: 2.04; 95% C.I:1.04, 4.03) and those who reported lack of PPE (AOR: 1.98; 95% C.I:1.04, 3.79) were more likely to be anxious.

Conclusions
The anxiety prevalence among healthcare professionals in Ethiopia during early stage of COVID-19 pandemic was high. This study shows that lack of preventive equipment, being female, contact with many patients, low self-efficacy and working in private health facilities were risk factors for anxiety. Anxiety prevention among health professionals during COVID-19 pandemic requires a holistic approach including provision of sufficient PPE, improving self-efficacy and addressing problems both at public and private institutions and focusing more on female health professionals.
Prioritizing solutions to incorporate Prosthetics and Orthotics services into Iranian health benefits package: Using an analytic hierarchy process
Authors: Shahabi Saeed , Pardhan Shahina , Ahmadi Teymourlouy Ahmad , Skempes Dimitrios , Shahali Shabnam , Mojgani Parviz , Jalali Maryam , Lankarani Kamran Bagheri 
Published: June 2021

Introduction
Health benefits package (HBP) is regarded as one of the main dimensions of health financing strategy. Even with increasing demands for prosthetics and orthotics (P&O) services to approximately 0.5% of the world’s population, only 15% of vulnerable groups have the chance to make use of such benefits. Inadequate coverage of P&O services in the HBP is accordingly one of the leading reasons for this situation in many countries, including Iran.

Aims
The main objective of this study was to find and prioritize solutions in order to facilitate and promote P&O services in the Iranian HBP.

Study design
A mixed-methods (qualitative-quantitative) research design was employed in this study.

Methods
This study was conducted in two phases. First, semi-structured interviews were undertaken to retrieve potential solutions. Then an analytic hierarchy process (AHP) reflecting on seven criteria of acceptability, effectiveness, time, cost, feasibility, burden of disease, and fairness was performed to prioritize them.

Results
In total, 26 individuals participated in semi-structured interviews and several policy solutions were proposed. Following the AHP, preventive interventions, infant-specific interventions, inpatient interventions, interventions until 6 years of age, and emergency interventions gained the highest priority to incorporate in the Iranian HBP.

Conclusion
A number of policy solutions were explored and prioritized for P&O services in the Iranian HBP. Our findings provide a framework for decision- and policy-makers in Iran and other countries aiming to curb the financial burdens of P&O users, especially in vulnerable groups.
Sistema Didático Elkonin-Davidov-Repkin
Authors: Damazio Ademir , Cunha André Luiz Araújo , Rosa Josélia Euzébio da 
Published: June 2021

O presente dossiê – Sistema Didático Elkonin-Davydov-Repkin, da Obutchénie: Revista de Didática e Psicologia Pedagógica (do Programa de Pós-Graduação em Educação e do Grupo de Estudos e Pesquisas em Didática Desenvolvimental e Profissionalização Docente (GEPEDI), da Faculdade de Educação, da Universidade Federal de Uberlândia – objetiva socializar um conjunto de estudos e pesquisas relativos às contribuições do referido sistema e da teoria do ensino desenvolvimental, formulada, inicialmente, por D. Elkonin, Vasili V. Davydov e um grupo de colaboradores, para o desenvolvimento na educação básica.
Inventário dos grupos brasileiros de pesquisa na teoria histórico-cultural a partir do Diretório de Grupos do CNPq
Authors: Asbahr Flávia da Silva Ferreira , Oliveira Miriam Laís Setti de Almeida Marcelo 
Published: June 2021

Este documento visa apresentar uma lista dos 115 grupos de pesquisa localizados na investigação intitulada “A Psicologia Histórico-Cultural na pesquisa brasileira: levantamento dos grupos de pesquisa cadastrados no diretório do CNPq”. A pesquisa teve como objetivo geral investigar a inserção da Psicologia Histórico-Cultural ou Teoria Histórico-Cultural no âmbito da investigação científica no Brasil, em grupos de pesquisa que a indicam formalmente como norteadora para os trabalhos. Um de nossos objetivos específicos, cujo resultado consta neste documento, foi identificar grupos de pesquisa cadastrados no Diretório de Grupos de Pesquisa do Conselho Nacional de Desenvolvimento Científico e Tecnológico (DGP-CNPq) que apontassem a Psicologia ou Teoria Histórico-Cultural como referencial teórico assumido. Entende-se que a apresentação do resultado bruto de pesquisa, ou seja, quais foram os 115 grupos localizados, pode constituir-se em importante fonte para outras investigações sobre a Teoria Histórico-Cultural no Brasil, bem como facilitar o intercâmbio e a divulgação científica entre grupos.
Keterlambatan Pelaporan Dalam Akuisisi Oleh Pt Nippon Indosari Corpindo Tbk; Studi Atas Putusan KPPU No. 07/KPPU-M.2018
Authors: Fadhil Rahmat , Farihah Ipah 
Published: June 2021

Studi ini bertujuan untuk menganalisis ketidak sesuaian sanksi denda yang dijatuhkan oleh Komisi Pengawas Persaingan Usaha pada perkara keterlambatan pelaporan akuisisi saham oleh PT. Nippon Indosari Corpindo Tbk dengan nomor perkara yaitu 07/KPPU-M/2018. Perbedaaan penjatuhan sanksi denda yang dijatuhkan oleh majelis komisi pengawas persaingan usaha dengan peraturan perundang-undangan tentu menjadi keputusan yang tidak sah dan sangat merugikan. Tetapi dalam menjalankan tugasnya komisi pengawas persaingan usaha diberi kebebasan untuk menentukan jumlah sanksi denda yang akan dijatuhkan berdasarkan pertimbangan-pertimbangan yang didapat didalam persidangan dan hasil penyelidikan.Tipe penelitian ini adalah penelitian hukum dengan pendekatan Yuridis Normatif, dikatan demikian karena dalam penelitian ini digunakan cara-cara pendekatan terhadap masalah dengan meninjau dari segi peraturan perundang-undangan yang berlaku atau melakukan penelitian dari bahan pustaka yang ada. Data yang digunakan adalah data sekunder yang berupa bahan hukum primer, bahan hukum sekunder, dan bahan hukum tersierHasil dari penelitian ini memperlihatkan bahwa terlapor diputuskan oleh majelis komisi bersalah dan membayar denda sebesar Rp 2.800.000.000,00 ( dua miliar delapan ratus juta rupiah). Komisi Pengawas Persaingan Usaha diberikan kewenangan seluas-luasnya untuk menetapkan denda yang sesuai denagn pertimbangan-pertimbangan yang jelas yang didapat oleh majelias dari penyelidikan dan kesaksian dalam persidangan
Estimating Earthquake Probabilities by Jaynes’s Method of Maximum Entropy
Authors: Bookstein Fred L. 
Published: June 2021

ABSTRACTAn important midcentury statistical method, already applied in several other scientific disciplines, enables epistemic ignorance to be incorporated more fully in multidecadal earthquake forecasts. Codified by the physicist E. T. Jaynes in the 1950s, the method of maximum entropy (MaxEnt) is suited for settings of great epistemic uncertainty. Shortly after its initial formulation it was being applied by industrial engineers to rates of failure and expected lifetimes—engineering problems analogous to fault ruptures and their recurrence intervals. Here, I show how MaxEnt can improve upon previous estimates of time-dependent conditional probabilities in Cascadia, California, and New Zealand. The method formalizes probabilistic inferences from long geology-based earthquake histories as truncated-Gaussian curves of time-dependent hazard that match the observed mean and mean square of the historical recurrence data. For each example, rupture forecasts by Brownian passage time, lognormal, Weibull, or Poisson methods have been published previously. In the Cascadia example, the MaxEnt estimate for a 50 yr exposure, 8.3%, compares with previous estimates of up to 14% for passage time or lognormal models. For other datasets drawn from the third Uniform California Earthquake Rupture Forecast study of California earthquakes and from the southern Alpine fault of New Zealand, MaxEnt recurrence probabilities similarly differ by up to a factor of nearly 2.0 from estimates published earlier. The lognormal approach is a variant of the MaxEnt model in which the estimate’s constraints concern the logarithms of the observed recurrence intervals; there is a continuum of methods in between. The discrepancies between MaxEnt and these other probability claims are not trivial; they arise from assumptions built into other methods that do not correspond to the actual information content of the data at hand. Discrepancies like these are directly relevant to the communication of these aspects of earthquake hazards to stakeholders concerned with the consequent risks.
On the Common Features of Reservoir Water-Level Variations and Their Influence on Earthquake Triggering: An Inherency of Physical Mechanism of Reservoir-Triggered Seismicity
Authors: Gahalaut Kalpna 
Published: June 2021

ABSTRACT
Impoundment of hydroelectric water reservoir influences the stability of nearby faults that may lead to reservoir-triggered seismicity (RTS). Various qualitative empirical relations, relating reservoir water-level variations with earthquake triggering and their frequency, have been deduced. With the goal to give a theoretical causation (in terms of time) to these empirical relations, a detailed theoretical analysis of the physical mechanism of RTS phenomenon, in terms of mechanical loading and changes in the pore-fluid boundary condition in the underlying rockmass, is undertaken. Three components, namely elastic stress, diffusion pore pressure, and stress-induced pore pressure, are simulated by considering a simple and schematic reservoir water-level time series using the Green’s function solution of poroelastic equations and frictional failure criterion. Various factors may influence the occurrence of RTS, but here definite role and nature of the poroelastic components in governing the empirical relations are simulated. The analysis suggests that (1) all the components contribute in RTS cases that are associated with higher reservoir water level, (2) diffusion pore pressure contributes mainly in RTS cases that are associated with longer duration of high reservoir water level, and (3) contribution of stress-induced pore pressure dominates in the RTS cases that are associated with rate of change of reservoir water level. Further, detailed simulations corroborate that the rapid type of earthquake triggering in RTS cases is mainly influenced by the immediate increase of stress and stress-induced pore pressure, whereas delayed type of triggering is mainly influenced by the diffusion pore pressure, and continuing type of triggering, inter alia, is influenced by the effect of dynamic changes in seasonal water cycle on the three components. The analyses lead us to conclude that the empirical relations are governed by the physical mechanism of RTS within the ambit of poroelastic theory.
Smile makeover with porcelain laminate veneer: A case report
Authors: Nazir Omaisa , Gaur Abhishek , Kumar Pandey Kaushik , Mishra Swati , Anwar Rubina , Sonali  
Published: June 2021

Pincus is credited for evolution of porcelain veneers. He attached the thin labial porcelain veneers temporarily with denture adhesive powders to improve dental esthetic appearance. Improvement of patient’s lost natural dental esthetics have become important goal of discipline of dentistry and credited for wide ranging applications from improving common man’s appearance to filmstars. Esthetic problems may be result of interplay of complex factors like color, shape, and structural and position abnormalities of anterior teeth. Laminate veneers are used for purpose of improving esthetic deficiencies and discolorations as well as existing abnormalities.Successful application of porcelain veneers depends on multiple factors such as the clinical and laboratory steps involved, along with the understanding of the scientific background of procedure.Conservative and esthetic approaches, such as direct and indirect laminate veneer restorations are most preferred way chosen by dentist across world to improve compromised esthetics of human beings. Technological advancements such as intraoral scanner for impression making have significantly improved the success of prosthesis.
Pengaruh Diabetes Self-Management Education and Support (DSME/S) Terhadap Kualitas Hidup pada Pasien Diabetes Melitus Tipe 2
Authors: Anggraeni Anis Fitri Nurul , Rondhianto Rondhianto , Juliningrum Peni Perdani 
Published: June 2021

Type 2 DM is a chronic disease requiring long-term care, so it needs self-management education toprevent the complication. The patient's inability to perform self-care can reduce the quality of life. DSME/Sis one of education which facilitates knowledge, skills, patient abilities, and family support in self-care.DSME/S is given in the form of discharge planning to improve knowledge and skills in self-care. Thisresearch aimed to analyze the effect of Diabetes Self-Management Education and Support (DSME/S) onquality of life of patients with type 2 diabetes mellitus in RSD dr. Soebandi. The research design wasquasi experimental with pre-test post-test with control group design. A number of samples were 30 peopledivided into two groups: 15 people in the treatment group and 15 people in the control group. DSME/Swas conducted in 6 sessions. Sessions 1-4 were performed in the hospital and sessions 5-6 wereperformed at the patient’s home. The data were analyzed by using dependent t test and independent ttest which significance level of 0.05. The result of t-dependent test indicated that there was significantdifferent quality of life between pre-test and post-test in the treatment group (p = 0.001) and control group(p = 0.002). The result of Independent t test showed a significant difference between treatment group andcontrol group (p = 0.001). The enhancement of quality of life on the treatment group was greater than thecontrol group. The conclusion showed that there was significant effect of DSME/S on the quality of life oftype 2 DM patients. DSME/S could improve patient self-care knowledge and abilities in controlling bloodsugar and prevent complications may effect of quality of life. Nurses can apply DSME/S in healthpromotion programs to type 2 DM patients in hospital.
Keywords: Type 2 diabetes mellitus, quality of life, DSME/S