bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adherence to conflicts of interest policy in Cochrane reviews where authors are also editorial board members: A cross‐sectional analysis
Authors: Pacheco Rafael Leite , Latorraca Carolina Oliveira Cruz , Martimbianco Ana Luiza Cabrera , Miranda Enderson , Fontes Luis Eduardo Santos , Nunan David , Riera Rachel 
Published: June 2021

AbstractCochrane devolves most editorial governance of the Cochrane Database of Systematic Reviews (CDSR), including title prioritization, protocol registration, peer‐review, editorial oversight and subsequent review deposition, to specific Cochrane Review Group (CRG) editorial boards. Current Cochrane policy stipulates authors of reviews who are also members of the supporting CRG declare this non‐financial conflict of interest and confirm no involvement in the review editorial process. The aim of this cross‐sectional analysis was to assess adherence to Cochrane's editorial conflict of interest policy. All 260 published Cochrane reviews (CR) in issues 1 to 6 from 2019 of the CDSR were reviewed. A total of 133 (51.2%, 133/260) of CRs had at least one author that was also listed as an editor in the CRG. Of these, only five (3.8%, 5/133) appropriately declared the conflict according to Cochrane policy. In 6.5% (17/133) CRs, the contact author had a leading editorial position within the CRG and in only four of 17 was this declared according to Cochrane policy. No CR with the contact author who also had a leading editorial position described methods to prevent any potential issues related to this scenario during the editorial process in accordance with Cochrane policy. We propose a specific form to improve the transparency and reliability of editorial conflict of interest reporting in CRs. The suggested form can be adapted to other contexts.
Determination of acyclovir and its metabolite 9‐carboxymethoxymethylguanide in human serum by ultra‐high‐performance liquid chromatography‐tandem mass spectrometry
Authors: Urinovska Romana , Kacirova Ivana , Sagan Jiri 
Published: June 2021

AbstractA simple and rapid ultra‐high‐performance liquid chromatography coupled with mass spectrometry method was developed for acyclovir and its metabolite 9‐carboxymethoxymethylguanine in human serum. After precipitation of serum samples with 0.1% formic acid in acetonitrile/methanol (40:60, v/v), components were separated on a Luna Omega C18 column (1.6 μm; 2.1 × 150 mm) at 40°C. Mobile phase A (2 mmol/L ammonium acetate, 0.1% formic acid in 5% acetonitrile, v/v/v) and mobile phase B (2 mmol/L ammonium acetate, 0.1% formic acid in 95% acetonitrile, v/v/v) were used for gradient elution. A linear calibration curve was obtained over the range of 0.05–50 mg/L, and the correlation coefficients were better than 0.999. The limit of quantitation was 0.05 mg/L for both analytes. The intra‐ and interday accuracy and precision at three concentration levels ranged between 1.6 and 13.3%, and recoveries were achieved with a range between 92.2 and 114.2%. This method was developed and validated for the therapeutic monitoring of acyclovir in patients.
Combining Low Power Fractional CO2 With QS‐NdYAG Toning in the Treatment of Melasma Reduces the Incidence of Punctate Leukoderma
Authors: Esmat Samia , Z. Elramly Amany , Shahin Dina , Hilal Rana F. 
Published: June 2021

Background and ObjectivesQ‐switched Nd:YAG (QS‐Nd:YAG) toning (low fluence, large spot size, and high frequency) has been used successfully for the treatment of melasma, especially in dark skin phototypes. Punctate leukoderma was found to be a frequent complication that reduced the safety of this procedure. Combining low power fractional CO2 laser, which is another effective melasma laser therapy, might improve the efficacy and safety of this procedure. The aim of this study was to evaluate the effect of combining low power fractional CO2 laser with QS‐Nd:YAG toning in the treatment of melasma.Study Design/Materials and MethodsA randomized comparative split‐face study included a total of 30 patients with bilateral, symmetrical melasma. All patients received QS‐Nd:YAG toning on one randomly selected side of the face, while the other side randomly received either low power fractional CO2 alone (group A) or combined QS‐Nd:YAG toning with low power fractional CO2 (group B). QS‐Nd:YAG toning sessions were scheduled every two weeks for nine consecutive sessions, and low power fractional CO2 sessions were received every 4 weeks for three consecutive sessions. The assessment was done using the modified melasma area and severity index (mMASI) score, spectrophotometry (melanin index [MI] and erythema index [EI]), photography, blinded physician assessment, and patient satisfaction (at baseline, 1 week and 8‐12 weeks after the last treatment sessions).ResultsA significant reduction in the mMASI score and MI was obtained with all treatment regimens. On comparing different modalities, group A reduction in mMASI and MI was significantly greater on the side receiving QS‐ND:YAG toning (64.03% and 8.27%, respectively), than the side receiving low power fractional CO2 laser alone (36.02%. 2.64%, respectively). On the other hand, reduction of mMASI score and MI showed no statistical significance between the side receiving QS‐Nd:YAG toning alone and the combined modality. Punctate leukoderma occurred in four cases (13%) on the side receiving QS‐Nd:YAG toning.ConclusionQS‐Nd:YAG toning is significantly more effective than low power fractional CO2 in the treatment of melasma when used separately. Although combining low power fractional CO2 with QS‐Nd:YAG toning does not increase its efficacy, it minimizes the incidence of the undesirable punctate leukoderma complication and achieves lower recurrence. This combination can thus be recommended as a safe and effective measure for the treatment of melasma. © 2021 Wiley Periodicals LLC.
Participation amongst people ageing with neuromuscular disease: a qualitative study of lived experiences
Authors: Møller Louise Abildgaard , Martinsen Bente , Werlauff Ulla , Dreyer Pia 
Published: June 2021

AbstractAimTo explore the lived experiences of participation in everyday life ageing with neuromuscular disease (NMD).DesignA qualitative study using a phenomenological‐hermeneutic approach.MethodsData were gathered through interviews with 15 persons living with NMD in 2018. A three‐levelled analysis and interpretation influenced by Paul Ricoeur's philosophy were conducted.The Consolidated Criteria for Reporting Qualitative Research (COREQ) checklist was used from May 2018 to December 2018.ResultsThree themes were identified: “Endless adaptations change the fundamentals of everyday life ageing with NMD,” “The ‘swamp’ of deterioration” is traversed through experiences of belonging and relationship,” “Being disabled by a professional knowledge gap and stereotypical images.” In these themes, the experience of participation in everyday life ageing with NMD appeared to depend on the ability to adapt constantly. Through participation, a sense of belonging and purpose was maintained. Lack of knowledge amongst professionals may negatively affect the ongoing participation of people ageing with NMD.
Self‐Lowering as Power and Trap: Wawa, ‘White’, and Peripheral Embrace of State Formation in Indonesian Papua
Authors: Stasch Rupert 
Published: June 2021

ABSTRACTBuilding on Ferguson's account of ‘declarations of dependence’ and prior Melanesianist work on ‘humiliation’, I examine how enthusiasm for state‐formation among Korowai of Papua has been shaped by their understandings of self‐lowering as a politically complex way of influencing kin and equalizing relations. I begin with media firestorms in Australia and urban Papua about the need to save two vulnerable boys. Korowai understandings of these episodes, unknown to faraway media publics, illustrate their idea that self‐lowering toward a hoped favorable benefactor is a desirable way of exercising a degree of relational control in a wider situation of being dominated. Building on the Australia‐linked Wawa affair, I look further at why sending boys to school in towns is a main strategy by which Korowai try to ameliorate their felt inferiority to city people. Transactions between schoolboys and senior relatives are politically complex, in ways that suggest the schooling strategy is an application of old egalitarian kinship techniques to new geopolitical inequalities. Finally, I look at Korowai responses to the new environment of large money flows into the countryside under government policies of redistricting and community‐driven development. Strong Korowai interest in benefactor relations with ‘Regency’ leaders, and the new embrace of divisions between ‘heads’ and ‘community’ within villages, also exemplify a strategy of seeking out a more livable relation of inequality to ease a less livable one.
A new reutilization strategy of waste printed circuit board nonmetal powders for constructing superhydrophobic coatings
Authors: Liu Wei , Hu Dechao , Liu Huaqing , Ma Wenshi 
Published: June 2021

AbstractReutilization of waste printed circuit board nonmetal powders (WPCBP) has been one of the major bottlenecks in the comprehensive utilization of electronic wastes. Herein, a new reutilization strategy of WPCBP was innovatively proposed to develop a superhydrophobic coating. Typically, WPCBP@SiO2hybrid filler was successfully prepared by the in‐situ growth of silica on WPCBP surface, and the structures and compositions of WPCBP@SiO2were systematically investigated by SEM, FTIR, and TGA. Then the obtained WPCBP@SiO2was combined with polydimethylsiloxane (PDMS) to prepare a superhydrophobic coating. The as‐prepared PDMS/WPCBP@SiO2coatings exhibited excellent superhydrophobicity and self‐cleaning ability, whose static water contact angle (WCA) is more than 150° while the sliding angle (SA) is <10°. In summary, this study provides a green and efficient reutilization strategy of WPCBP in superhydrophobic coatings, which may open up a new opportunity for the high‐valued utilization of WPCBP.
Investigation of the Ablative Properties of an EPDM\Kevlar Insulator in a Solid Rocket Motor
Authors: Sapozhnikov Igor , Leitner Amiram , Natan Benveniste , Mograbi Elaad 
Published: June 2021

AbstractA study of the influence of the reinforced fiber orientation and the propellant aluminum content on the ablation and erosion performance of Ethylene Propylene Diene Monomer type insulation is presented. A subscale solid rocket motor has been used, with ammonium perchlorate and hydroxyl‐terminated polybutadiene propellant composition. Seven static firing tests were conducted: six with low Al and one with high Al content. The EPDM articles had four different Kevlar fiber orientations: circumferential, longitudinal, diagonal (45°), and random. Numerical simulations were supplemented to decipher the experimental outcome. The numerical results exhibit an over‐prediction tendency, yet they show that the examination of post‐fire charring of the insulation is insignificant. The test results indicate that the longitudinal fiber orientation has the least ablative resistance.
Epicuticular hydrocarbons of the redbanded stink bug Piezodorus guildinii (Heteroptera: Pentatomidae): sexual dimorphism and alterations in insects collected in insecticide‐treated soybean crops
Authors: Sessa Lucía , Calderón‐Fernández Gustavo M. , Abreo Eduardo , Altier Nora , Mijailovsky Sergio J , Girotti Juan R , Pedrini Nicolás 
Published: June 2021

AbstractBACKGROUNDThe redbanded stink bug Piezodorus guildinii (Heteroptera: Pentatomidae) is one of the most important species affecting soybean crops in southern South America. Capillary gas chromatography coupled to mass spectrometry was used to characterize the epicuticular hydrocarbon profiles of field‐collected insects, and to identify differences in their composition between fifth‐instar nymphs and adults, males and females, and between bugs collected in insecticide‐treated and insecticide‐free soybean crops.RESULTSStraight chain saturated n‐C27 and n‐C29, and monomethyl and dimethyl chains of C31 and C33 were the most abundant compounds. A group of volatile hydrocarbons with n‐C13 and n‐C15 as the predominant compounds were also detected. The hydrocarbon pattern was different between nymphs and adults, either males or females. Heneicosene was almost exclusively detected in adult males and was the most important component to differentiate between both sexes, followed by tricosadiene. The total hydrocarbon amount was significantly higher in nymphs, males and females collected in insecticide‐treated fields compared with insects obtained from untreated fields.CONCLUSIONDifferences were found in the epicuticular hydrocarbon pattern among nymphs and adults, as well as sexual dimorphism in adult stink bugs. Interestingly, an alteration was also found in the hydrocarbon profile of insects collected in insecticide‐treated soybean crops and its relevance is discussed within a pest management context.
Quantitative prediction of breast cancer resistant protein mediated drug‐drug interactions using physiologically‐based pharmacokinetic modeling
Authors: Costales Chester , Lin Jian , Kimoto Emi , Yamazaki Shinji , Gosset James R. , Rodrigues A. David , Lazzaro Sarah , West Mark A. , West Michael , Varma Manthena V. S. 
Published: June 2021

AbstractQuantitative assessment of drug‐drug interactions (DDIs) involving breast cancer resistance protein (BCRP) inhibition is challenged by overlapping substrate/inhibitor specificity. This study used physiologically‐based pharmacokinetic (PBPK) modeling to delineate the effects of inhibitor drugs on BCRP‐ and organic anion transporting polypeptide (OATP)1B‐mediated disposition of rosuvastatin, which is a recommended BCRP clinical probe. Initial static model analysis using in vitro inhibition data suggested BCRP/OATP1B DDI risk while considering regulatory cutoff criteria for a majority of inhibitors assessed (25 of 27), which increased rosuvastatin plasma exposure to varying degree (~ 0–600%). However, rosuvastatin area under plasma concentration‐time curve (AUC) was minimally impacted by BCRP inhibitors with calculated G‐value (= gut concentration/inhibition potency) below 100. A comprehensive PBPK model accounting for intestinal (OATP2B1 and BCRP), hepatic (OATP1B, BCRP, and MRP4), and renal (OAT3) transport mechanisms was developed for rosuvastatin. Adopting in vitro inhibition data, rosuvastatin plasma AUC changes were predicted within 25% error for 9 of 12 inhibitors evaluated via PBPK modeling. This study illustrates the adequacy and utility of a mechanistic model‐informed approach in quantitatively assessing BCRP‐mediated DDIs.
A review of the research progress of interventional medical equipment and methods for prostate cancer
Authors: Wang Lifeng , Zhang Yongde , Zuo Sihao , Xu Yong 
Published: June 2021

AbstractBackgroundProstate cancer is a common disease in men and has a relatively high mortality rate. However, the interventional medical equipment used for prostate biopsy and brachytherapy has always been a social concern.MethodsTo understand interventional medical equipment for prostate cancer, the structure of manual, semi‐automatic and automatic medical equipment were considered as the mainline, while the corresponding research on these structures were the auxiliary lines. The characteristics and corresponding research status have been discussed.ResultsInterventional medical equipment for prostate cancer with different degrees of automation and its characteristics were determined, and the imaging principles and characteristics of computed tomography, transrectal ultrasound and magnetic resonance imaging have been briefly described.ConclusionCertain feasible research suggestions have been proposed for future development from the perspective of structure, accuracy and safety. These include flexible and compact robot structures, high‐precision image recognition and guidance, accurate dose planning and monitoring, real‐time imaging monitoring without delay, high‐precision needle insertion strategy, master‐slave control, virtual reality and remote control.
The Effect of (3‐Mercaptopropyl)trimethoxysilane (MPS) Coating on the Genetic Detection Performance of Quartz Crystal Microbalance‐Dissipation (QCM‐D) Biosensor: Novel Intact Double‐Layered Surface Modification on QCM‐D
Authors: Soysaldı Furkan , Soylu Mehmet Çağrı 
Published: June 2021

AbstractBiosensor's ability depends on both platform performance and surface modification. In mass sensitive biosensors, a stable coating with molecular structural dynamism increases sensitivity. Also, its orientation and smoothness directly affect the performance of cross‐linker molecules and receptors. In this study, the performance of intact double‐layered (ID) coating used on QCM−D for the first time in DNA detection of MPS was investigated. The sensitivity of the QCM−D with ID‐MPS was compared to the uncoated. At the concentrations of 1010 and 1013 copies/mL, the method with ID‐MPS was approximately 6.4 times more sensitive. A shift of 1.22(±0.42) Hz was observed at the detection limit at 108 copies/mL, while it was 0.19(±0.05) Hz in the negative control. Thus, a signal‐to‐noise‐ratio greater than 3, which is a measure of signal quality in biosensors, was exceeded with a ratio of 3.33, and it was shown that the detection signal at the sensitivity limit was sufficient. In addition, the two methods were compared visually with atomic force microscopy in terms of the amount and distribution of captured molecules, and it was determined that the ID‐MPS was more efficient.
Fabrication of Reduced Graphene Oxide‐Silver/Polyvinyl Alcohol Nanocomposite Film for Reduction of 4‐Nitrophenol and Methyl Orange Dye
Authors: Sharma Keshav , Majhi Shukla , Ali Mohd. , Singh Renuka , Shekhar Pati Tripathi Chandra , Guin Debanjan 
Published: June 2021

AbstractThe development of ingenious technologies for the purification of wastewater containing highly toxic organic compounds is of high importance in the current research. The application of noble metal nanocatalysts in the presence of sodium borohydride (NaBH4) for the removal of these toxic compounds through chemical reduction method have become an accepted approach in the recent years. The present work reports on the development of a convenient approach to fabricate free standing, robust, and flexible reduced graphene oxide ‐ silver/polyvinyl alcohol (rGO−Ag/PVA) nanocomposite film. The morphological and structural characterizations of the as developed film have been carried out using SEM, TEM, EDAX, Raman, BET, and TGA. The performance of as developed rGO−Ag/PVA nanocomposite film is tested as heterogeneous catalyst in the reduction reaction of 4‐Nitrophenol and reduction of Methyl Orange dye. The nanocomposite film‐based catalyst exhibited excellent catalytic performances as well as excellent stability in the reduction of toxic organic compounds in wastewater.
Inverted Polymer Solar Cells with Annealing‐Free Solution‐Processable NiO
Authors: Tran Hong Nhan , Dao Duc Quang , Yoon Yung Jin , Shin Yun Seop , Choi Jin San , Kim Jin Young , Cho Shinuk 
Published: June 2021

AbstractNickel oxide (NiO) offers intrinsic p‐type behavior and high thermal and chemical stability, making it promising as a hole transport layer (HTL) material in inverted organic solar cells. However, its use in this application has been rare because of a wettability problem caused by use of water as base solvent and high‐temperature annealing requirements. In the present work, an annealing‐free solution‐processable method for NiO deposition is developed and applied in both conventional and inverted non‐fullerene polymer solar cells. To overcome the wettability problem, the typical DI water solvent is replaced with a mixed solvent of DI water and isopropyl alcohol with a small amount of 2‐butanol additive. This allows a NiO nanoparticle suspension (s‐NiO) to be deposited on a hydrophobic active layer surface. An inverted non‐fullerene solar cell based on a blend of p‐type polymer PTB7‐Th and non‐fullerene acceptor IEICO‐4F exhibits the high efficiency of 11.23% with an s‐NiO HTL, comparable to the efficiency of an inverted solar cell with a MoOx HTL deposited by thermal evaporation. Conventionally structured devices including this s‐NiO layer show efficiency comparable to that of a conventional device with a PEDOT:PSS HTL.
Recent progress on precious metal single atom materials for water splitting catalysis
Authors: Zhou Lei , Lu Shi‐Yu , Guo Shaojun 
Published: June 2021

AbstractElectrochemical water splitting for hydrogen production has sparked intensive interests because it provides a new approach for sustainable energy resources and the avoidance of environmental problems. The precious metal‐based single atomic catalysts (PMSACs) have been widely employed in water splitting catalysis by virtue of their maximum atom utilization and unique electronic structure, which can reduce metal amounts and remain high catalytic performance simultaneously. In this review, we will summarize recent research efforts toward developing SACs based on precious metals with excellent performance for electrochemical water splitting catalysis. First, the synthesis strategies for PMSACs will be classified and introduced including high‐temperature pyrolysis, electrochemical method, photochemical reduction, wet chemistry method, etc. Then, a short description of characterization techniques for SACs will be given, which mainly involves the aberration‐corrected scanning‐transmission electron microscopy (AC‐STEM) and X‐ray absorption spectroscopy (XAS). In particular, the relationship between the electronic structure of the precious metal atomic sites and performance for water splitting will be discussed according to the theoretical and experimental results. Finally, a brief perspective will be provided to highlight the challenges and opportunities for the development of novel PMSACs suitable for electrochemical water splitting applications.
Introduction and Overview
Authors: Kern Margaret L. , Wehmeyer Michael L. 
Published: June 2021

AbstractOver the past decade, the positive education movement has grown, with the rapid increase of research, curricula, programs, and approaches to supporting wellbeing within educational communities. We introduce positive education, unpacking the positive perspective, considering how positive education emerged from this perspective, and discussing the implications moving forward. We then provide an overview of the chapters within this Handbook. Aligned with the valuing of open dialogue and diverse perspectives, authors provide various definitions of, perspectives around, and approaches to positive education. The Handbook attempts to give light to the plurality of models and perspectives, highlights high-quality research and research-to-practice efforts, incorporates a broad range of topics, and includes international and multi-disciplinary approaches. As a whole, the Handbook aims to support collective efforts to create and shape educational environments that allow all members of our educational communities to thrive, both now and for future generations.
Assessing Wellbeing in School Communities
Authors: Jarden Aaron , Jarden Rebecca , Chin Tan-Chyuan , Kern Margaret L. 
Published: June 2021

AbstractThis chapter summarizes the essentials of assessment, principles of good assessment, and wellbeing assessment in the context of school communities. Drawing from positive education initiatives, what wellbeing assessments in schools look like, and why they are important is outlined and discussed. Examples of good assessment tools and their use in practice are explored. The chapter further focuses on the content, processes, and systems involved in assessment, before addressing the use of assessment data in decision-making and providing examples of good assessment in practice. The chapter ends by highlighting questions schools and decision-makers may draw from in choosing and developing assessment tools and approaches for their unique school community.