bluuebunny/crossref_metadata_2025_split huggingface dataset:
What are community perspectives and experiences around low testosterone? A cross-sectional study in the UK
Authors: Liu Vivian , Huang David , Alaa Aos , Hayhoe Benedict , El-Osta Austen 
Published: December 2024

Abstract

Background
Prevalence of late-onset testosterone deficiency (TD) differs amongst studies, with estimates between 6-30% depending on diagnostic criteria used. Nonspecific symptoms and lack of symptom awareness often delays appropriate treatment.
Methods
A 54-item online survey investigated the prevalence of TD symptoms and experiences of men on treatment. The survey was distributed through online media channels, Prolific and academic networks. Symptoms were assessed using the qADAM questionnaire. Associations between age, qADAM scores and participant demographics were assessed using logistic regressions to understand the prevalence and barriers to accessing treatment.
Results
Of the 973 men, nearly half (49%) indicated high likelihood of TD using qADAM scores, despite only 4% being formally diagnosed. Men over 50 had 1.4-2.0 times higher odds of TD compared to younger men (OR51-60yrs_vs_<40yrs:1.43, p=0.05; OR60+years_vs_<40yrs:2.03, p=0.001). 30% reported low libido, 7% reported reduced erectile strength, and 26% reported over three symptoms associated with TD. Despite high symptom prevalence, awareness and uptake of treatment remained low. 56% were unfamiliar with symptoms and signs associated with low testosterone. Only 7% of individuals expressed satisfaction with their access to low testosterone resources in the UK. Key barriers to seeking medical advice or treatment included lack of awareness of symptoms (40%), financial costs (34%) and stigma surrounding hormonal health (29%).
Conclusions
Although nearly half of individuals exhibited a high likelihood of TD, over 95% remained undiagnosed. This highlights significant gaps in symptom awareness and access to treatment options, including the need to improve health literacy around TD to democratise access to care.
Transformer-Based Tool for Automated Fact-Checking of Online Health Information: Development Study
Authors: Bayani Azadeh , Ayotte Alexandre , Nikiema Jean Noel 
Published: December 2024

Background
Many people seek health-related information online. The significance of reliable information became particularly evident due to the potential dangers of misinformation. Therefore, discerning true and reliable information from false information has become increasingly challenging.

Objective
This study aimed to present a pilot study in which we introduced a novel approach to automate the fact-checking process, leveraging PubMed resources as a source of truth using natural language processing transformer models to enhance the process.

Methods
A total of 538 health-related web pages, covering 7 different disease subjects, were manually selected by Factually Health Company. The process included the following steps: (1) using transformer models of bidirectional encoder representations from transformers (BERT), BioBERT, and SciBERT, and traditional models of random forests and support vector machines, to classify the contents of web pages into 3 thematic categories (semiology, epidemiology, and management), (2) for each category in the web pages, a PubMed query was automatically produced using a combination of the “WellcomeBertMesh” and “KeyBERT” models, (3) top 20 related literatures were automatically extracted from PubMed, and finally, (4) the similarity checking techniques of cosine similarity and Jaccard distance were applied to compare the content of extracted literature and web pages.

Results
The BERT model for the categorization of web page contents had good performance, with F1-scores and recall of 93% and 94% for semiology and epidemiology, respectively, and 96% for both the recall and F1-score for management. For each of the 3 categories in a web page, 1 PubMed query was generated and with each query, the 20 most related, open access articles within the category of systematic reviews and meta-analyses were extracted. Less than 10% of the extracted literature was irrelevant; those were deleted. For each web page, an average of 23% of the sentences were found to be very similar to the literature. Moreover, during the evaluation, it was found that cosine similarity outperformed the Jaccard distance measure when comparing the similarity between sentences from web pages and academic papers vectorized by BERT. However, there was a significant issue with false positives in the retrieved sentences when compared with accurate similarities, as some sentences had a similarity score exceeding 80%, but they could not be considered similar sentences.

Conclusions
In this pilot study, we have proposed an approach to automate the fact-checking of health-related online information. Incorporating content from PubMed or other scientific article databases as trustworthy resources can automate the discovery of similarly credible information in the health domain.
mHealth App to Promote Healthy Lifestyles for Diverse Families Living in Rural Areas: Usability Study
Authors: Perez Ramirez Alejandra , Ortega Adrian , Stephenson Natalie , Muñoz Osorio Angel , Kazak Anne , Phan Thao-Ly 
Published: December 2024

Background
Mobile Integrated Care for Childhood Obesity is a multicomponent intervention for caregivers of young children with obesity from rural communities that was developed in collaboration with community, parent, and health care partners. It includes community programming to promote healthy lifestyles and address social needs and health care visits with an interdisciplinary team. A digital mobile health platform—the Healthy Lifestyle (Nemours Children’s Health) dashboard—was designed as a self-management tool for caregivers to use as part of Mobile Integrated Care for Childhood Obesity.

Objective
This study aimed to improve the usability of the English and Spanish language versions of the Healthy Lifestyle dashboard.

Methods
During a 3-phased approach, usability testing was conducted with a diverse group of parents. In total, 7 mothers of children with obesity from rural communities (average age 39, SD 4.9 years; 4 Spanish-speaking and 3 English-speaking) provided feedback on a prototype of the dashboard. Participants verbalized their thoughts while using the prototype to complete 4 tasks. Preferences on the dashboard icon and resource page layout were also collected. Testing was done until feedback reached saturation and no additional substantive changes were suggested. Qualitative and quantitative data regarding usability, acceptability, and understandability were analyzed.

Results
The dashboard was noted to be acceptable by 100% (N=7) of the participants. Overall, participants found the dashboard easy to navigate and found the resources, notifications, and ability to communicate with the health care team to be especially helpful. However, all (N=4) of the Spanish-speaking participants identified challenges related to numeracy (eg, difficulty interpreting the growth chart) and literacy (eg, features not fully available in Spanish), which informed iterative refinements to make the dashboard clearer and more literacy-sensitive. All 7 participants (100%) selected the same dashboard icon and 71% (5/7) preferred the final resource page layout.

Conclusions
Conducting usability testing with key demographic populations, especially Spanish-speaking populations, was important to developing a mobile health intervention that is user-friendly, culturally relevant, and literacy-sensitive.
“Seeking a better life”: Identity of Tanzanian urban residents
Authors: Ivanchenko O. V. 
Published: December 2024

The paper is based on the results of field research conducted by the author in the United Republic of Tanzania in November 2023, focusing on the issue of nation formation in the multiethnic state. The study was carried out in Dar es Salaam and Bagamoyo cities, resulting in the collection of 33 formal and informal interviews in English and Swahili. The key aim of the research was to find out whether the national component of self-identity has taken precedence for Tanzanian citizens, or if local identities, ethnic or regional, remain more significant. Tanzania is characterized by very high rate of urbanization, and making the issue of changing identity under the new conditions especially relevant for understanding the adaptation mechanisms of migrants in the cities. It is important to note that in Tanzanian cities the majority of residents are at most, second- or third-generation urban residents. Young people usually move to the city alone, without family. Those who were born in the city usually have only parents and siblings living there. Thus, connections to the culture of one’s region of origin are often broken, leading to a search for new affiliations, which frequently involves a shift in self-identity.In the article we will examine issues of the transformation and significance of ethnic identity; the relationship between ethnic, regional, and national levels of self-identity; attitudes towards ethno-racial minorities; and the future of indigenous Tanzanian cultures, languages, and traditions within the multicultural environment of the city.
NILAI PERUSAHAAN: ANALISIS FAKTOR YANG MEMPENGARUHINYA
Authors: Kurniawan Lydia , Mahardini Swesti , Patricia Patricia 
Published: December 2024

Penelitian ini bertujuan menguji secara empiris apakah profitabilitas, pertumbuhan penjualan, dan leverage berpengaruh terhadapNilai Perusahaan pada Perusahaan retail sub sektor makanan dan minuman yang terdaftar di Bursa Efek Indonesia tahun 2019-2023. Penelitian ini menggunakan data sekunder dan sample penelitian ini yang digunakan peneliti adalah Perusahaan retail yang terdaftar di bursa efek Indonesia tahun 2019-2023yang menggunakan metode purposive sampling. Dalam penelitian ini terdapat 95 populasi perusahaan yang terdaftar di bursa efek Indonesia dan didapatkan 28 sample Perusahaan. Analisis data yang digunakan adalah aplikasi E-Views12. Hasil penelitian ini menunjukkan bahwa profitabilitas berpengaruh terhadap nilai perusahaan, pertumbuhan penjualan tidak berpengaruh terhadap nilai perusahaan, dan leverage berpengaruh terhadap nilai perusahaan.Novelty penelitian ini adalah variable penelitian diantaranya profitabilitas, pertumbuhan penjualan, leverage, dan nilai Perusahaan, peneliti juga melakukan pembaharuan terhadap waktu atau periode yang menjadi 2019-2023, peneliti melakukan seleksi dalam penentuan sample penelitian
Rancang Bangun Lampu Spot Panggung dan Dimmer Lampu Otomatis Menggunakan Voice Recognition V3 Berbasis Mikrokontroller
Authors: Candra Oriza , Ihsan Fadilatul , Yolanda Rafika , Amini Aisyah 
Published: December 2024

Pada era sekarang ini, penggunaan lampu sorot (spotlight) masih menggunakan tenaga manusia sebagai pengoperasiannnya. Hal ini sangat tidak efektif, untuk mengoperasikan lampu sorot (spotlight) pada panggung dan ruangan. Lampu spotlight biasanya digunakan untuk memfokuskan suatu objek dalam kegiatan penting, seperti prosesi acara seminar, konser, dan acara indoor lainnya. Spotlight tersebut perlu dikendalikan dan dijalankan secara otomatis tanpa bantuan tenaga manusia dengan bantuan sensor suara dengan perintah suara untuk menjalankannya. Artikel ini bertujuan untuk merancang lampu sorot (spotlight) panggung dan dimmer lampu otomatis menggunakan Voice Recognition V3 berbasis mikrokontroler. Desain ini menggunakan arduino uno atmega328P sebagai pusat pemprosesan kendali sesuai dengan input yang diberikan. Input akan disimpan dan diproses mikrokontroler sesuai program yang digunakan, Voice Recognition V3 sebagai sensor suara yang berfungsi sebagai pendeteksi dan memberikan perintah berupa file suara yang telah disimpan, outputnya akan menggerakan motor pada lampu sorot, AC Light Dimmer berfungsi untuk mengatur dimmer intensitas cahaya pada panggung atau ruangan sesuai lumen lampu yang ditentukan dan lampu akan redup apabila Voice recognition memberikan perintah suara, modul relay pada alat ini sebagai saklar on/off pada lampu yang akan menghidupkan pada alat, dan Motor stepper penggerak pada spotlight. Setelah melakukan pengujian dan analisa terhadap Spotlight pada panggung dan dimmer lampu otomatis menggunakan Voice Recognition V3 berbasis mikrokontroler ini dapat diambil kesimpulan bahwa secara keseluruhan alat ini telah bekerja dengan baik sesuai rancangan prinsip kerjanya dan hasil yang dicapai sesuai fungsi dan kerja alat.
Rancang Bangun Prototype Smarthome berbasis Mikrokontroler NodeMCU
Authors: Fahmi Bahrul , Myori Dwiprima Elvanny 
Published: December 2024

Teknologi terbukti efektif dalam meningkatkan produktivitas manusia di era modern. Namun tidak se marak smartpone, beberapa teknologi masih belum dapat di jangkau oleh sebagian orang. Seperti smarthome¸ smarthome sangat sulit dijangkau karena ketidaktahuan masyarakat umum tentang pembuatan smarthome sederhana. Tujuan dari penelitian ini adalah mengetahui pembuatan smarthome sederhana dan mengetahui efektivitas pengguna terhadap penggunaan smarthome dan dapat diterapkan dengan mudah hanya menggunakan jaringan WiFi dan Smartphone. Alat ini menggunakan nodemcu sebagai pusat pemprosesan data dan modul wi-fi, solenoid doorlock dan sensor MQ2 sebagai sistem keamanan rumah, relay dengan input 4 buah lampu, dan motor DC sebagai penggerak pagar otomatis, semuanya dikendalikan menggunakan smartphone. Setelah pengujian dan analisa prototype smarthome menggunakan nodemcu, alat ini dapat bekerja sesuai dengan baik, kecepatan kerja alat sesuai jaringan Wi-Fi pengguna. Pengguna dapat meningkatkan kerja smarthome dengan penggunaan jaringan Wi-FI yang baik. Berdasarkan penelitian ini, dapat di simpulkan bahwa alat ini bekerja dengan baik sesuai dengan rancangan prinsip kerjanya dan mendapatkan hasil yang baik. Penggunaan smarthome sangat efektif dan bermanfaat untuk tempat tinggal manusia era modern.
ICONOGRAPHIC ORIGINS OF " TIARA" OF TIGRAN THE GREAT
Authors: MARTIROSYAN MADONA 
Published: December 2024

In the ancient systems of the world, the main persons-kings, rulers - carried an important philosophical distinguishing element, wore a ceremonial crown hats. They differed both in their appearance and content. crown-Khur told about the position of the wearer, achievements, titles received.
Khuri-Crowns had not only the meaning of transmission of dynastic succession, but also had a spiritual and secular philosophical nature. Such was also the "Armenian Crown" of Tigran the Great, the king of Armenia.
The object of the study is the iconography of the Armenian crown of Tigran the Great.
The purpose of this study is to The Armenian crown of Tigran the Great is the crown depicted in ancient high sculptures, sculptures, on carved stones and coins, which was worn by Tigran the Great, his successors and the Yervandun kings of the related Kommagenian branch in solemn circumstances. The crown of Tigran the Great was created on the basis of a religious idea. It is a reflection of the supposed subordinate of the god Mihr. It is of native Armenian origin and is not an imitation of any royal foreign khuri.
The methodological basis of the research was the analytical-comparative, historical-comparative, and chronological-descriptive methods.
As a result of the study, it was established that. The iconographic origins of Tigran the Great's crown originated from the ancient rock paintings in the Armenian highlands and, receiving the right of institutional identity, after undergoing certain polishing, entered the iconography of the deities of the Kingdom of Van (Khaldi, Teisheba, Shivini), passed to the deity Mihri, the kingdom of Yervandi, the kings of Commagene and Tsopk to the Mashtotsian alphabet and appeared in their improved version on the crowns of the Armenian king Tigran the Great, Artavazd and other Artashesian kings. By combining and discussing the results of the studies of historians-researchers G.A.Tiratsyan, B.Tashjian, Z.Khachatryan, R.Sullivan, Father Vardan Hatsun and others, we came to the conclusion that the Armenian Tigranyan crown, having an initial similarity with the Persian crown, however, it is of Armenian origin and was drawn and prepared according to the ideas of its master, Tigran the Great, to perceptions in accordance with the position. It is the result of the absolute interweaving of the spiritual and secular authorities of the centuries-old history of the Armenian people, as evidenced by the example of rock paintings, inscriptions and monuments of the Armenian Highlands.
CHARACTERISTICS OF THE HIERARCHY OF MOTIVES IN STUDENTS’ EDUCATIONAL MOTIVATION
Authors: ARAKELYAN ANNA , AVAGYAN ANI 
Published: December 2024

ANNA ARAKELYAN, ANI AVAGYAN
The article discusses the issues of students' educational motivation and the effectiveness of educational activities, presents the results of the research conducted among the students of ASPU after Kh. Abovyan. There were 115 second- and third-year students of the Department of Psychology of the Faculty of Educational Psychology and Sociology who took part in the research. In order to study the peculiarities of students' educational motivation, the motivation studying methodology was used for educational activities (changed by A. A. Ryan, V. A. Yakunin). As a result of the research data, the 5 main motivations of students' educational activities, which are considered to be most important for them, were identified, and the structure of educational motivation in general was analyzed.
Body composition and nutritional status in nursing home residents during the COVID-19 lockdown: a 15-month follow-up
Authors: Cvijetić Selma , Keser Irena , Ilich Jasminka Z. 
Published: December 2024

Abstract
Since the beginning of the corona virus disease (COVID-19) pandemic, nursing home residents had been under strict quarantine, which greatly affected their lifestyle and health. In this follow-up study, we analysed whether lifestyle changes during the lockdown had an impact on their body composition and nutritional status. For this purpose we determined body composition, nutritional status, and osteosarcopenic adiposity (OSA) prevalence in 24 volunteer nursing home residents just before the February 2020 COVID-19 lockdown and about 15 months into the lockdown. Body composition (total bone mass, lean and fat tissue components) was assessed with bioelectrical impedance. OSA was established if the participants had sarcopenia, osteopenia, and adiposity. Information on dietary habits, weight loss, and selfperception of health were obtained with the Mini Nutritional Assessment (MNA) form, while nutritional status was assessed with the MNA-Short Form (SF). At baseline, OSA was determined in 14 participants and at the follow-up in 16 participants. The results show an overall decrease in bone and lean tissues and increase in fat tissue. There were significantly more participants with a normal nutritional status than those at risk of malnutrition or malnourished (p=0.045). Our findings suggest that negative changes in body composition during the pandemic are owed to age rather than to changes in lifestyle caused by the pandemic. Regular monitoring of body composition in nursing homes may help to preserve the health of older people in general and particularly in cases of possible future lockdowns.
An in vitro evaluation of the cytotoxic potential of medicinal mushrooms against human breast cancer cell lines
Authors: Topalović Dijana , Živković Lada , Borozan Sunčica , Santibanez Juan F. , Spremo-Potparević Biljana 
Published: December 2024

Abstract
Medicinal mushroom extracts, i.e. their dried biomass, have long been known as sources of bioactive compounds with positive effects on the human health. The antioxidant, antigenotoxic, antiviral, and immunomodulatory properties of the commercially available extracts Agaricus blazei auct. non Murrill (AB), Cordyceps sinensis (Berk.) Sacc. (CS), and Immune Assist (IA) have already been documented. This study, studied the influence of these three mushrooms on the viability of cell lines MCF-7, MDA-MB-231, and HS-5. The cytotoxicity of AB, CS, and IA at different concentrations (25, 50, 100, 200, 400 and 800 μg/mL) was evaluated using the MTT assay. The results showed that AB was the most effective and induced cytotoxicity in both cancer cell lines, with IC50 values of 96.7 μg/mL for MCF-7 and 368.4 μg/mL for MDA-MB-231. After treatment with CS and IA, the half-maximal inhibitory concentration was reached only in MDA- MB-231 cells (IC50=613 μg/mL for CS and 343.3 μg/mL for IA). We have shown here that AB, CS and IA can suppress the growth of MCF-7 and MDA-MB-231 cell lines, while affecting the survival of healthy HS-5 cells to a much lesser extent. Our in vitro results suggested that AB, CS and IA are promising natural sources with potential anticancer activity.
What is more common in fatal caffeine intoxication – suicide or unintentional overdose?
Authors: Lušić Dražen , Bezak Sara , Karačonji Irena Brčić 
Published: December 2024

Abstract
Caffeine is a natural stimulant of plant origin found in many products such as coffee, tea, chocolate, and energy drinks. It is also often used as an active substance in over-the-counter drugs such as painkillers and preparations for the treatment of colds and allergies. While caffeine is generally considered safe when moderately consumed, excessive intake in a single dose or through repeated small doses over time can lead to caffeine intoxication. Symptoms of caffeine intoxication can vary depending on the amount of caffeine consumed and can include restlessness, rapid heart rate, muscle tremors, nausea, vomiting, and confusion. In severe cases, caffeine intoxication can lead to convulsions, coma, and even death. This mini-review presents an overview of caffeine’s characteristics and intoxication including symptoms, causes, diagnosis, and treatment. It addresses risk factors associated with caffeine intoxication and presents current recommendations for safe caffeine consumption. The studies we have reviewed suggest that in cases of fatal caffeine intoxications, intentional intoxication is more common than unintentional.
Comparison of different disinfection protocols against contamination of ceramic surfaces with Klebsiella pneumoniae biofilm
Authors: Piletić Kaća , Mežnarić Silvestar , Keržić Eli , Oder Martina , Gobin Ivana 
Published: December 2024

Abstract
Environmental contamination with Klebsiella pneumoniae biofilm can be a source of healthcare-associated infections. Disinfection with various biocidal active substances is usually the method of choice to remove contamination with biofilm. In this study we tested 13 different disinfection protocols using gaseous ozone, citric acid, and three working concentrations of benzalkonium chloride-based professional disinfecting products on 24-hour-old biofilms formed by two K. pneumoniae strains on ceramic tiles. All tested protocols significantly reduced total bacterial counts compared to control, varying from a log10 CFU reduction factor of 1.4 to 5.6. Disinfection combining two or more biocidal active substances resulted in significantly better anti-biofilm efficacy than disinfection with single substances, and the most effective combination for both strains was that of citric acid, gaseous ozone, and benzalkonium chloride. This follow up study is limited to K. pneumoniae alone, and to overcome this limitation, future studies should include more bacterial species, both Gram-positive and Gramnegative, and more samples for us to find optimal disinfection protocols, applicable in real hospital settings.