bluuebunny/crossref_metadata_2025_split huggingface dataset:
Linking empowerment, engagement, communication and organizational health: moderated mediation model
Authors: Singh Anupama 
Published: November 2021

PurposeThis paper aims to examine the factors that mediate and moderate the relationship between psychological empowerment and organizational health. Specifically, work engagement is posited to mediate the relationship between psychological empowerment and organizational health and organizational communication to moderate the relationship between psychological empowerment and work engagement.Design/methodology/approachData were collected from 524 scientists belonging to 10 laboratories of CSIR – an Indian R&D organization. For statistical analysis of moderated-mediation model, hierarchical multiple regression and process macro for SPSS was used.FindingsResults revealed that work engagement was found to mediate the positive relationship between psychological empowerment and organizational health and organizational communication moderated the influence of psychological empowerment on work engagement. Results of moderated-mediation revealed that mediation of work engagement was moderated by organizational communication such that at higher levels of communication, the mediating effect of work engagement became stronger.Originality/valueThis study extends the understanding of the organizational health concept by studying the mediating effect of work engagement being moderated by organizational communication and its subsequent impact on organizational health.
Gender detransition: a case study
Authors: Marchiano Lisa 
Published: November 2021

AbstractWithin the last decade, there has been a sharp global rise in the number of young people identifying as transgender. More recently, there appears to be an increase in the numbers of young people detransitioning or returning to identifying with their natal sex after pursuing medical transition. A case is presented of a young woman who pursued a gender transition and returned to identifying as female after almost two years on testosterone. The author considers and critiques the affirmative model of care for gender dysphoric youth in light of this case.
Machine perfusion organ preservation: Highlights from the American Transplant Congress 2021
Authors: Pavan‐Guimaraes Juliana , Zarrinpar Ali , Beduschi Thiago , Atkinson Carl , Martins Paulo N. 
Published: November 2021

AbstractThe American Transplant Congress 2021 was a virtual meeting and occurred between June 4 and June 9 through an online platform. We highlighted abstracts discussing machine perfusion preservation, a hot topic that may become the gold standard of organ preservation in the future. A total of 33 abstracts on organ machine preservation (3 for heart, 4 for lungs, 18 for liver, and 8 for kidneys) were presented at the meeting. We selected 23 abstracts that showed advances including new approaches to organ preservation, promising treatments and biomarkers, cellular therapy, and novel research areas. Here, we summarize the new developments concerning machine perfusion in both experimental and clinical studies.
Peripheral corneal thickness and associated factors – results from the population‐based German Gutenberg Health Study
Authors: Fieß Achim , Marx‐Groß Susanne , Wasielica‐Poslednik Joanna , Nagler Markus , Schmidtmann Irene , Wild Philipp S. , Münzel Thomas , Beutel Manfred E. , Lackner Karl J. , Pfeiffer Norbert , Schuster Alexander K. 
Published: November 2021

AbstractPurposeChanges in peripheral corneal thickness are described in various corneal diseases such as corneal ectasia. However, few data exist describing the increase in corneal thickness from central to peripheral and reporting the normal distribution of corneal thickness in rings around the corneal centre. The aim of this study was to report these cornea characteristics and investigate associated factors in a population‐based setting.MethodsThe Gutenberg Health Study is a prospective, population‐based study examining participants in a 5‐year follow‐up (age range 40–80 years) using Scheimpflug imaging. Corneal thickness was assessed in each participant at the apex, as well as in the corneal centre (thinnest corneal thickness) and in rings with 2, 4, 6, 8 and 10 mm diameter around the corneal centre, and the increase in corneal thickness towards the periphery. The relationship between corneal thickness at these locations and possible associated factors was determined using linear regression models. For this purpose, general and ocular parameters were included.ResultsA total of 9729 participants were included in the present analysis (4874 women, age 59.2 ± 10.8 years). Multivariable analysis showed a correlation between the increase in corneal thickness in the circles from 0 to 10 mm (diameter) and the following parameters: age (B = −0.24 µm per year, p < 0.001); body height (B = −0.04 µm, p = 0.005); smoking (B = −0.72 µm, p < 0.001); spherical equivalent (B = −0.70 µm per dioptre, p < 0.001); white‐to‐white distance (B = −0.75 µm/mm, p < 0.001); mean corneal radius (B = −3.61 µm/mm, p < 0.001); intraocular pressure (B = −0.12 µm/mmHg, p < 0.001); glaucoma (B = −1.94 µm, p < 0.001); and pseudophakia (B = 0.89 µm, p < 0.001).ConclusionThe results of the present study suggest that several general and ocular parameters are associated with peripheral corneal thickness. In the context of diagnosing glaucoma, a smaller increase in corneal thickness towards the periphery might be a new additional marker.
Epithelioid hemangioma involving large arteries in the skin
Authors: Markidan Janina , Hardy Naomi , Kallen Michael , Ma Linglei 
Published: November 2021

AbstractEpithelioid hemangioma (EH) is a benign vascular lesion, typically consisting of small vascular channels lined by epithelioid endothelial cells and associated with a dense lymphocytic infiltrate with eosinophils. Here, we report a rare case of EH involving large arteries. The patient presented with a 9‐month history of an asymptomatic nodule on the forehead, which was thought to be an epidermal inclusion cyst. Skin biopsy revealed large arteries with clusters of epithelioid cells in the vascular walls and lumen. Scattered eosinophils were noted in the walls. Adjacent areas showed groups of small‐caliber vessels lined by prominent endothelial cells and associated with a dense lymphoid infiltrate with eosinophils. No significant cytologic atypia was noted. Given the presence of the classic small‐vessel involvement, along with CD31 reactivity for the epithelioid cells in the large vessels, the findings are classified as EH involving large arteries, which is an uncommon subtype. There have only been a handful of such cases reported in the literature.
IFN‐γ‐induced PD‐L1 expression on human melanocytes is impaired in vitiligo
Authors: Willemsen Marcella , Krebbers Gabrielle , Tjin Esther P. M. , Willemsen Karin J. , Louis Alesha , Konijn Veronique A. L. , Narayan Vidhya S. , Post Nicoline F. , Bakker Walbert J. , Melief Cornelis J. M. , Bekkenk Marcel W. , Luiten Rosalie M. 
Published: November 2021

AbstractMounting evidence shows that the PD‐1/PD‐L1 axis is involved in tumor immune evasion. This is demonstrated by anti‐PD‐1 antibodies that can reverse tumor‐associated PD‐L1 to functionally suppress anti‐tumor T‐cell responses. Since type I and II interferons are key regulators of PD‐L1 expression in melanoma cells and IFN‐γ‐producing CD8+ T cells and IFN‐α‐producing dendritic cells are abundant in vitiligo skin, we aimed to study the role of PD‐1/PD‐L1 signalling in melanocyte destruction in vitiligo. Moreover, impaired PD‐1/PD‐L1 function is observed in a variety of autoimmune diseases. It is, therefore, hypothesized that manipulating PD‐1/PD‐L1 signalling might have therapeutic potential in vitiligo. The PD‐1+ T cells were abundantly present in situ in perilesional vitiligo skin, but expression of PD‐L1 was limited and confined exclusively to dermal T cells. More specifically, neither melanocytes nor other epidermal skin cells expressed PD‐L1. Exposure to IFN‐γ, but also type I interferons, increased PD‐L1 expression in primary melanocytes and fibroblasts, derived from healthy donors. Primary human keratinocytes only showed increased PD‐L1 expression upon stimulation with IFN‐γ. More interestingly, melanocytes derived from non‐lesional vitiligo skin showed no PD‐L1 upregulation upon IFN‐γ exposure, while other skin cells displayed significant PD‐L1 expression after exposure. In a vitiligo skin explant model, incubation of non‐lesional vitiligo skin with activated (IFN‐γ‐producing) T cells from vitiligo lesions was previously described to induce melanocyte apoptosis. Although PD‐L1 expression was induced in epidermal cells in these explants, this induction was completely absent in melanocytes. The lack of PD‐L1 upregulation by melanocytes in the presence of IFN‐γ‐producing T cells shows that melanocytes lack protection against T‐cell attack during vitiligo pathogenesis. Manipulating PD‐1/PD‐L1 signalling may, therefore, be a therapeutic option for vitiligo patients.
Origen’s Theological System in On First Principles
Authors: Fernández Samuel 
Published: November 2021

AbstractThis article aims to reconsider Origen’s theological system in the light of his treatise On First Principles. Was Origen a systematic thinker? If so, what kind of systematicity characterised his theology? Since the reception of the treatise was marked by theological quarrels, it is not possible to isolate its theology from the problems related to the transmission of the text. Therefore, the first part of the article tackles the text of On First Principles (I). The second part studies the structure, addressees and aim of the treatise; the paper then moves on to a discussion of the nature of Origen’s systematic thinking, and an analysis of the pre‐existence of the soul to disclose the theological rationale lying behind On First Principles (II). Finally, the article outlines the theology of the treatise with a special focus on the two main features of Origen’s systematic thinking: its aspiration to reach coherence and comprehensiveness. To grasp the deep consistency of Origen’s thought, it is necessary to contemplate the history of salvation as a whole (III).
Understanding innovation policy governance: A disaggregated approach
Authors: Zhang Xiaoke 
Published: November 2021

AbstractThis article presents a disaggregated approach to understanding innovation policy governance. It first develops a conceptual framework for differentiating innovation policy domains in terms of the complexity of governance problems and for describing governance approaches and outcomes. The article then advances a theoretical explanation of divergent governance patterns by granting causal primacy to the interplay between government structures and interactive arrangements. It contends that these socio‐political institutions interact differently to structure the resolution of governance problems and thus generate divergent patterns of innovation policy governance. The article illustrates the empirical relevance of its theoretical framework and explanation through a comparative analysis of innovation policy governance in four East Asian economies.
Local implementation evaluation of a suicide prevention predictive model at a large VA health care system
Authors: du Pont Alta , Stanley Ian H. , Pruitt Larry D. , Reger Mark A. 
Published: November 2021

AbstractBackgroundThe Veterans Health Administration (VHA) implemented REACH VET, which analyzes health records to identify veterans at statistically elevated risk for suicide and other adverse outcomes compared to other veterans in VHA. This project evaluated REACH VET program implementation at a large VA health care system by examining program fidelity and treatment engagement, receipt of suicide prevention interventions, and suicide‐related behaviors in the 6 months following identification.MethodsOver a 12‐month period, 218 unique cases were identified by REACH VET within a local VA system. Data were extracted from the VA’s electronic medical records.ResultsProtocol adherence for required clinical and administrative steps was 94% and above. After identification, 88% received outpatient mental health treatment, 21% had a psychiatric hospitalization, and 83% engaged in Safety Planning around the time of identification or in the following six months. Twenty‐six percent of cases were identified by another existing method for identifying high‐risk veterans. Five percent had a medically documented suicide attempt, and none were known to die by suicide in the following 6 months.ConclusionsLocal evaluation suggested high protocol fidelity and high engagement in mental health and suicide prevention services following identification among veterans who remained at elevated risk in the 6 months that followed.
Tensile and Fracture Characterization of PVC Foam Cores
Authors: Viana Gilmer M. , Carlsson Leif A. 
Published: November 2021

Abstract
Mechanical behavior in tension and fracture toughness of cross-linked PVC foams have been characterized. Young’s modulus, yield strength and fracture toughness data were compared to micro-structural relations derived for open and closed-cell foams. The failure process and stress strain response were indicative of brittle material behavior.
Dynamic Failure Mechanisms in 3D Cellular Woven Composite Systems
Authors: Baucom Jared N. , Zikry Mohammed A. , Qiu Yiping 
Published: November 2021

Abstract
The role of porosity on failure resistance of 3-D woven fiber reinforced epoxy panels under dynamic loading condition is investigated. Incident and residual velocities are measured to determine the energy absorption by the target. Material behavior segregates by porosity, and the more highly porous samples absorb a greater amount of specific energy. The reason for this may be due to the deflection of matrix cracks by pores or due to the greater flexibility of the fibers to absorb energy through tensile straining. Although porosity is generally an undesirable property in textile composites, the induction of porosity may result in reduced panel weight without degradation of ballistic performance, which is a clear advantage for weight minimization.
Methods and Tools for the Design of Mechatronic Products Concepts and Examples From the University of Darmstadt
Authors: Anderl Reiner , Kleiner Sven 
Published: November 2021

Abstract
This paper describes the academic program of Mechanical and Process Engineering at Darmstadt University of Technology in Germany. The faculty is offering courses in general mechanical engineering, mechatronics as well as paper science and technology and chemical engineering. A closer look will be provided on design methodologies on one hand and computer aided methods and tools on the other hand in order to show the importance of teaching these specific classes. As a consequence of efficient curriculum structure of the faculty, two examples will be used to illustrate the results of project and research work in cooperation between the Department of Computer Integrated Design and students.
Dispatching of Coordinated Proximity Sensors for Object Surveillance
Authors: Naish Michael D. , Croft Elizabeth A. , Benhabib Beno 
Published: November 2021

Abstract
This paper presents a method of selecting and positioning groups of sensors in a coordinated manner for the surveillance of a maneuvering object The object trajectory is discretized into a number of demand instants (data acquisition times) to which groups of sensors are assigned, respectively. Heuristic rules are used to evaluate the suitability of each sensor for servicing (observing) a demand instant, determine the composition of the sensor group, and, in the case of dynamic sensors, specify the position of each sensor with respect to the object This approach aims to improve the quality of the surveillance data in three ways: (1) the assigned sensors are maneuvered into “optimal” sensing positions, (2) the uncertainty of the measured data is mitigated through sensor fusion, and (3) the poses of the unassigned sensors are adjusted to ensure that sensing-system can react to object maneuvers. Simulations with proximity sensors demonstrate the advantages of dispatching dynamic sensors over similar static-sensor systems.
Time-Optimal Path Planning and Control Using Neural Networks and a Genetic Algorithm
Authors: Chaiyaratana Nachol , Zalzala Ali M. S. 
Published: November 2021

Abstract
This paper presents the use of neural networks and a genetic algorithm in time-optimal control of a closed-loop 3-dof robotic system. Extended Kohonen networks which contain an additional lattice of output neurons are used in conjunction with PID controllers in position control to minimise command tracking errors. The results indicate that the extended Kohonen network controller is more efficient than the trajectory preshaping scheme reported in early literature. Subsequently, a multi-objective genetic algorithm (MOGA) is used to solve an optimisation problem related to time-optimal control. This problem involves the selection of actuator torque limits and an end-effector path subject to time-optimality and tracking error constraints. Two chromosome coding schemes are explored in the investigation: Gray and integer-based coding schemes. The results suggest that the integer-based chromosome is more suitable at representing the decision variables. As a result of using both neural networks and a genetic algorithm in this application, an idea of a hybridisation between a neural network and a genetic algorithm at the task level for use in a control system is also effectively demonstrated.
Preemptive Control of Multiply Actuated Processes: Application to Moisture Content Control in Paper Manufacturing Using Surrogate Measurements
Authors: Li Perry Y. , Bjegovic Petar J. , Ramaswamy Shri 
Published: November 2021

Abstract
Many manufacturing processes involve the successive processing of the substrate at multiple station on a transport medium, with the hope that at the end of the process, the product has the desired property. Paper manufacturing is an example in which over 90% of the water from pulp is sequentially removed through gravity, vacuum dewatering, pressing, and thermal drying. The consistency and uniformity of the moisture content at the end of process is important for paper quality. Current strategy for the control of moisture content uses a feedback sensor at the end of the process to adjust the dryers. This introduces a long deadtime and causes excessive use of the dryers, which translate to limitations in performance, robustness and inefficient energy usage. In this paper, we investigate a new control approach in which in-process moisture contents are estimated using air-flow as surrogate measurements, and the pressure settings in the multiple vacuum dewatering boxes are adjusted according to the surrogate measurements. A preemptive control algorithm is developed which has the ability to decouple and eliminate the effects of the disturbances that occur upstream in the process from downstream. Robustness analysis and simulation studies suggest that as long as the surrogate measurements are accurate, the proposed control scheme will be robust and accurate.
State-Space Modeling and Control of Acoustic Systems
Authors: Kashani Reza , Mohammad Asim S. 
Published: November 2021

Abstract
Synthesis and analysis of model-based controllers for an acoustic system require the state-space formulation of the system. The use of modal data, i.e. resonant frequencies, model damping ratios, and mode shapes, in constructing state-space model of an aoucstic system is described in this paper. Moreover, a simple, low-order feedback controller for adding damping to and/or cancelling offending noise in an acoustic system is introduced. State-space modeling, as well as the effectiveness of the proposed feedback controller are demonstrated through numerical and experimental, illustrative examples.
Experience With Sliding Mode Control of a Pneumatic Cartesian Robot
Authors: Surgenor Brian W. , Xia Yang 
Published: November 2021

Abstract
This paper outlines experience with a 3 axis pneumatic Cartesian robot that was constructed from commercially available valves and cylinders. Experiments demonstrate that a linear PVA controller is suitable for step tracking applications. However, acceptable performance was achieved only after extensive trial and error tuning of the controller gains. Preliminary gain estimates were obtained for PVA with a Linear Quadratic (LQ) design and a linear model of the robot. Sliding Mode Control (SLM) was found to be superior to PVA in that it provided acceptable performance with minimal tuning effort. The relay nature of SLM was also found to provide a measure of friction compensation. Preliminary results for SLM as applied to circle tracking are presented.
Identification of a Driver Steering Model, and Model Uncertainty, From Driving Simulator Data
Authors: Chen Liang-Kuang , Ulsoy A. Galip 
Published: November 2021

Abstract
Driver steering models have been extensively studied. However, driver model uncertainty has received relatively little attention. For active safety systems that function while the driver is still in the control loop, such uncertainty can affect overall system performance significantly. In this paper, an approach to obtain both the driver model and its uncertainty from driving simulator data is presented. The structured uncertainty is used to represent the driver’s time-varying behavior, and the unstructured uncertainty is used to account for unmodeled dynamics. The uncertainty models can be used to represent both the uncertainty within one driver and the uncertainty across multiple drivers. The results show that the unstructured uncertainty is significant, probably due to randomness in driver behavior. The structured uncertainty suggests that an estimation and adaptation scheme might be applicable for the design of controllers for active safety systems.
Tube Bending Process: Part I — Theory
Authors: Lieh Junghsen , Li Wei Jie 
Published: November 2021

Abstract
This paper contains two parts, Part-I is focused on simulation of nonlinear springback problems. In part II, a fuzzy control law is implemented in order to compensate the nonlinearity and uncertainty in tube bending. By combining elasticity and plasticity theories, a mathematical model for predicting springback is established and Simpson’s integration rule is adopted. The discrepancy between theoretical and experimental results is used to examine the accuracy of established model.
Path Planning for Motion Control of Hexapod Machines
Authors: Ji Zhiming , Li Zhenqun 
Published: November 2021

Abstract
The dramatic departure in structure of the hexapod machine tools from the traditional five-axis machines leads to the question: can the planning and control methods for the traditional CNC machines be used for the hexapod machine tools? We studied several tool motion characteristics, such as Jocabian matrices, path tracking errors and the extra degree of freedom (e-DOF), and found that the traditional five-axis planning methods cannot take into consideration of the kinematics performance variation and the e-DOF in a hexapod. A kinematics-based tool path planning scheme for the hexapods is therefore proposed. It combines the traditional tool path planning with the kinematic condition optimization. The optimization is a two-step process. First a high accuracy zone of the workspace is identified globally for the placement of the part. Then a set of 5-DOF tool paths is generated and extended to a set of 6-DOF tool paths based on the local planning of e-DOF. Finally the relationship between the e-DOF and the stiffness of the Hexapods, another factor in the use of e-DOF, are discussed.