bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pelayanan perpustakaan desa berbasis inklusi sosial di Perpustakaan Desa Jendela Dunia Kabupaten Kuningan Jawa Barat
Authors: Komariah Neneng , Saepudin Encang , Rukmana Evi Nursanti 
Published: June 2021

Introduction. A village library is a public library that support rural community education activities. The village library should be transformed into a sosial inclusion-based library. The paper aims to explore services and activities of Jendela Dunia Village Library based on sosial inclusion.
Data Collection Method. This paper used a qualitatative research method with a case study approach.
Data Analysis. The data collection techniques were conducted through interviews, observations, and library studies.
Results and Discussion. The Jendela Dunia Village Library has been run based on sosial inclusion considering aspects of collection development to support the needs of the community with a web-based digital library. Several activities have also been conducted such as organising training of computer, making handicrafts, arts, and gymnastics, organisings innovative KOBOK services, managing mobile reading bicycles, and supporting health literacy through Posyandu and Posbindu.
Conclusion. Jendela Dunia Village Library is a sosial inclusion-based library that is creatively managed and has the full support of the village leader. This can be a model for other village libraries in utilizing the potential of the village. Jendela Dunia Village Library also opens training sfor library managers outside the village.
Pengaruh algoritma filter bubble dan echo chamber terhadap perilaku penggunaan internet
Authors: Wulandari Virani , Rullyana Gema , Ardiansah Ardiansah 
Published: June 2021

Introduction. This study aims to explore effects of bubble filter and echo chamber on information searching behaviour on the internet, how it affects the scope of the internet ecosystem and users, and what we can see from the behaviour.
Data Collection Method. The paper used a mixed-methods approach with surveys, online discussions, and literature research. Twenty respondents between 19-21 years old participated in this exploratory study.
Analysis Data. Data was obtained and calculations have automatically accumulated through Google Form. The user data analysis and discussion were conducted manually by considering aspects of rationality concerning the literature and previous research.
Results and Discussions. The analysis results obtained were bubble filter and echo chambers were proven to affect internet users both in positive and negative ways.
Conclusions. Bubble filter and echo chamber may have both positive and negative effects simultaneously, however, it depends on the user because the system has provided control features to reduce both features. Using internet wisely is also parts of the important aspect.
Esplorasi website Perpustakaan Universitas Harvard, Universitas Gadjah Mada dan Universitas Telkom
Authors: Ridlo Muhammad Rasyid , Zain Robi Yoswan , Ginting Yesika Anggreini Br , Saputri Yoandini 
Published: June 2021

Introduction. This article evaluates library websites of world class universities in Indonesia from several aspects including features, responsibility, and speed. One library website overseas is explored as a reference: Harvard University.
Data Collection Method. This is a literature study exploring features on library websites of Universitas Gadjah Mada (UGM) and Telkom University.
Data analysis. The study used Harvard University library website as a reference. The results were presented into tables to discuss library websites of UGM and Telkom University.
Results and Discussion. Harvard University library webiste has 21 features except gallery, UGM has 11 features and Telkom University has 12 features similar to Harvard University library webiste. Our result showed that Library website of UGM and Telkom University still need to be improved as required to be a world class university. All three websites has an adjustable display depending on devices in accessing websites. Those three websites were considered as responsive websites. Based on PageSpeed Insight, they showed good performance.
Conclusion. Information on the websites are well-managed, informative, efficient, and accessible. Universities in Indonesia may use several overseas university library websites as a reference.
Peran Dinas Kearsipan dan Perpustakaan dalam preservasi dan komunikasi kebudayaan lokal Provinsi Jawa Tengah
Authors: Ganggi Roro Isyawati Permata , Dewi Athanasia Octaviani Puspita 
Published: June 2021

Introduction. The purpose of this paper is to explore the role of The Office of Archive and Library in preservation and communication of local culture.
Data Collection Method. Using a case study, this paper involved the data collection by interviews, observations and literature review.
Data Analysis. The data were descriptively analysed by using thematic analysis.
Results and Discussion. The Office of Archive and Library has three roles in preservation and communication of local culture. They are: (1) as an information provider; (2) as a local cultural preservation agency; and (3) as a communicator of local cultural information. The role in preservation and communication of local culture arises because of the duties of the Office of Archive and Library Office in managing knowledge and efforts to fulfill the intellectual needs of the community.
Conclusion. Preservation and communication of local culture conducted by the Office of Archive and Library Office is a manifestation of the function of library. The role in the preservation and communication of local culture will continue to develop in accordance with the user needs.
SCREENING ANTIBACTERIAL ACTIVITY OF VIETNAMESE PLANT EXTRACTS AGAINST HUMAN PATHOGENIC BACTERIA
Authors: NGO LONG HOANG , NGUYEN THI HAI YEN , TRAN VU KHAC , DOAN VU VAN , NGUYEN MINH VAN , BUI HIEU TRUNG 
Published: June 2021

Objectives: Infectious diseases caused by bacteria are a leading cause of death worldwide. Hence, the objectives of the study are aimed to evaluate the antibacterial activity against five human pathogenic bacteria of methanolic extracts from 66 plants collected from Vietnam.
Methods: The broth microdilution method was used to determine the minimum inhibitory concentration (MIC) of methanol extracts of 66 plant species against five bacterial strains.
Results: In this study, all the plant extracts were active against at least one train with MIC values ranging from 24 to 2048 μg/mL. Twenty-five plant extracts were active against all three Gram-positive bacteria (Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus). Of these, the extracts of Macaranga trichocarpa (Rchb. f. and Zoll.) Mull. Arg. (Euphorbiaceae), Calophyllum inophyllum L. (Clusiaceae) and Caryodaphnopsis baviensis (Lecomte) Airy Shaw (Lauraceae) exhibited the highest antibacterial activity (MIC =24–128 μg/mL), followed by extracts of Betula alnoides Buch.- Ham. e × . D. Don (Betulaceae), Acronychia pedunculata (L.) Miq. (Rutaceae), Croton alpinus A. Chev. ex Gagnep. (Euphorbiaceae) (MIC =64–256 μg/mL). Furthermore, the extract of Rhus chinensis Mill. (Anacardiaceae) and Annona reticulata L. (Annonaceae) exhibited potent antibacterial activity against the two Bacillus species (MIC =32–64 μg/mL).
Conclusion: Results of this study reveal that plant extracts from Vietnam have highly antibacterial activity against Gram-positive bacteria. These results suggest that Vietnamese plant extracts may be a rich source of antibacterial drugs.
DEVELOPMENT AND PERFORMANCE EVALUATION OF TUMOR TARGETING POTENTIAL OF FOLATE SPACER FUNCTIONALIZED SOLID LIPID NANOPARTICLES
Authors: SINGH SHIKHA , CHATURVEDI PRIYANKA , K JAIN SURENDRA 
Published: June 2021

Purpose: The objective of the present investigation was to assess the tumor-targeting potential of ligand-spacer engineered solid lipid nanoparticles (SLN) as nanoscale drug delivery units for site-specific delivery of a model anticancer agent, paclitaxel (PTX). SLNs were engineered by direct and indirect conjugation of folic acid (FA) through different types of polyethylene glycols (PEGs) (MW: 1000, 4000) as spacers.
Methods: The synthesized nanoconjugates (SLNFA, SLN1FA, and SLN4FA) were characterized by Fourier transform infrared spectroscopy, nuclear magnetic resonance, and transmission electron microscopic studies. Nanoconjugates were evaluated for entrapment, in vitro drug release (under various pH conditions) and hemolytic studies. Cell uptake and cytotoxicity studies were performed on human malignant cell lines (MCF-7) using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.
Results: This study explored the effect of PEG spacer length on the targeting potential of folate-conjugated SLN. PTX entrapment and in vitro drug release from nanoconjugates augmented, and hemolytic toxicity of nanoconjugates slashed with the molecular weight of PEGs. Further, nanoconjugates with PEG 4000 displayed highest tumor-targeting potential as compared to other spacer conjugated nanoconjugates due to optimized steric hindrance and receptor mediated endocytosis among other PEGs.
Conclusion: Engineering of the dendritic surface with targeting ligand such as FA can enhance the site-specific anticancer drug delivery. PEGylation of SLN can improve the circulation time of SLN in the body. This is a debut study reporting FA conjugation to the surface through four PEGs as spacer and optimized the spacer chain length for effective cancer targeting through SLN. This report as a whole is believed to shed new light on the role of spacer chain length in targeting potential of folate-anchored SLN.
A CLINICAL STUDY OF SIDDHA HERBAL PREPARATION – M V KASHAYAM FOR THE TREATMENT, CONTROL, AND MANAGEMENT OF COVID-19
Authors: SP MALARKANNAN , P DHARUMARAJAN , MK HARIYOHESH 
Published: June 2021

Objective: At present, the pandemic COVID-19 by novel coronavirus causing severe mortality and losses to the human and no specific medicine to cure. Siddha is an ancient system of medicine used in using a variety of medicinal herbs to cure diseases of viral and unknown origin.
Method: The herbal medicine M V Kashayam prepared as per Siddha formula administered at the dose rate of 150 ml for every 6-h interval for Reverse Transcription–Polymerase Chain Reaction (RT – PCR) positive patients
Results: The prepared MV Kashayam can able to provide RT-PCR negative in 87.5% of cases within 4–6 days and 97.5% negatives in 12 days. The body temperature, Oxygen saturation level (SPO2), and respiration level become normal within 3 days.
Conclusion: The Siddha medicine, MV kashayam may be used as herbal medicine to treat the COVID-19 patients for earlier recovery and as a preventive measure to enhance immunity.
O “QUINTAIS DE MEL”: A CRIAÇÃO DE ABELHAS SEM FERRÃO COMO FERRAMENTA DE EDUCAÇÃO AMBIENTAL
Authors: Silva Tiago Amaral , Felippsen Eduardo Alberto , Mandotti Sônia Maria , Simão Daniel Ferreira , Gimenes Gabriela Martines 
Published: June 2021

RESUMO: O “Quintais de Mel” é um projeto de extensão desenvolvido pelo Instituto Federal do Paraná em Assis Chateaubriand. O objetivo principal do projeto é promover a educação ambiental em escolas e comunidade em geral para então contribuir com a preservação das abelhas nativas sem ferrão. Para tanto, segue-se um percurso metodológico de quatro etapas no projeto. Primeiro a estruturação de um meliponário didático para manejo dos enxames das abelhas sem ferrão. Segundo, a promoção de ações educativas nas escolas do município de Assis Chateaubriand, como oficinas e palestras sobre a temática em questão. Terceira estimular a população atendida a criar abelhas nos próprios quintais de suas casas. A última etapa, trata-se da capacitação de pessoas interessadas na criação de abelhas sem ferrão e a produção de pasto meliponícola. Atualmente o projeto está com a maioria das atividades online, com a produção de conteúdos relacionados ao tema central, e os publica em redes sociais, assegurando as recomendações de isolamento social. Espera-se com o retorno de atividades presenciais no IFPR, que os estudantes das escolas atendidas pelo projeto, visitem o meliponário didático e tenham experiências com o manejo e cultura de preservação das abelhas nativas sem ferrão.
Palavras-chave: Polinizadores. Conservação. Sustentabilidade.
High Out-of-pocket Health Care Cost Burden Among Medicare Beneficiaries With Diabetes, 1999–2017
Authors: Park Joohyun , Zhang Ping , Wang Yu , Zhou Xilin , Look Kevin A. , Bigman Elizabeth T. 
Published: June 2021

OBJECTIVE
We examined the magnitude of and trends in the burden of out-of-pocket (OOP) costs among Medicare beneficiaries age 65 years or older with diabetes overall, by income level, by race/ethnicity, and compared with beneficiaries without diabetes.

RESEARCH DESIGN AND METHODS
Using data from the 1999−2017 Medicare Current Beneficiary Survey, we estimated average annual per capita OOP costs and percentage of beneficiaries experiencing high OOP burden, defined as OOP costs &gt;10% or &gt;20% of household income. We used joinpoint regression to examine the trends and generalized linear model and logistic regression for comparisons between beneficiaries with and without diabetes. Cost and income estimates were adjusted to 2017 USD.

RESULTS
Total OOP costs were $3,609–$5,283, with significant increases until 2005 followed by a leveling off. The prevalence of high OOP burden was 57%–72% at the 10% income threshold and 29%–41% at the 20% threshold, with significant increasing trends until 2003 followed by decreases. Total OOP costs were the highest in the ≥75% income quartile, whereas prevalence of high OOP burden was highest in the &lt;25% and 25–50% income quartiles. Non-Hispanic Whites had the highest OOP costs and prevalence of high OOP burden. Beneficiaries with diabetes had significantly higher OOP costs ($498, P &lt; 0.01) and were more likely to have high OOP burden than those without diabetes (odds ratios 1.32 and 1.25 at &gt;10% and &gt;20% thresholds, respectively, P &lt; 0.01).

CONCLUSIONS
Over the past two decades, Medicare beneficiaries age 65 years or older with diabetes have faced substantial OOP burden, with large income-related disparities.
Efficacy and Safety of Dapagliflozin by Baseline Glycemic Status: A Prespecified Analysis From the DAPA-CKD Trial
Authors: Persson Frederik , Rossing Peter , Vart Priya , Chertow Glenn M. , Hou Fan Fan , Jongs Niels , McMurray John J.V. , Correa-Rotter Ricardo , Bajaj Harpreet S. , Stefansson Bergur V. , Toto Robert D. , Langkilde Anna Maria , Wheeler David C. , Heerspink Hiddo J.L. 
Published: June 2021

OBJECTIVE
The Dapagliflozin and Prevention of Adverse outcomes in Chronic Kidney Disease (DAPA-CKD) study demonstrated risk reduction for kidney and cardiovascular outcomes with dapagliflozin versus placebo in participants with chronic kidney disease (CKD) with and without diabetes. We compared outcomes according to baseline glycemic status.

RESEARCH DESIGN AND METHODS
We enrolled participants with CKD, estimated glomerular filtration rate (eGFR) 25–75 mL/min/1.73 m2, and urinary albumin-to-creatinine ratio 200–5,000 mg/g. The primary composite end point was sustained eGFR decline ≥50%, end-stage kidney disease, or kidney or cardiovascular death.

RESULTS
Of 4,304 participants, 738 had normoglycemia, 660 had prediabetes, and 2,906 had type 2 diabetes. The effect of dapagliflozin on the primary outcome was consistent (P for interaction = 0.19) in normoglycemia (hazard ratio [HR] 0.62 [95% CI 0.39, 1.01]), prediabetes (HR 0.37 [0.21, 0.66]), and type 2 diabetes (HR 0.64 [0.52, 0.79]). We found no evidence for effect modification on any outcome. Adverse events were similar, with no major hypoglycemia or ketoacidosis in participants with normoglycemia or prediabetes.

CONCLUSIONS
Dapagliflozin safely reduced kidney and cardiovascular events independent of baseline glycemic status.
Advancing Therapy in Suboptimally Controlled Basal Insulin–Treated Type 2 Diabetes: Clinical Outcomes With iGlarLixi Versus Premix BIAsp 30 in the SoliMix Randomized Controlled Trial
Authors: Rosenstock Julio , Emral Rifat , Sauque-Reyna Leobardo , Mohan Viswanathan , Trescolí Carlos , Al Sifri Saud , Lalic Nebojsa , Alvarez Agustina , Picard Pascaline , Bonnemaire Mireille , Demil Nacima , McCrimmon Rory J. 
Published: June 2021

OBJECTIVE
To directly compare the efficacy and safety of a fixed-ratio combination, of insulin glargine 100 units/mL and the glucagon-like peptide 1 receptor agonist lixisenatide (iGlarLixi), with those of a premix insulin analog, biphasic aspart insulin 30 (30% insulin aspart and 70% insulin aspart protamine) (BIAsp 30) as treatment advancement in type 2 diabetes suboptimally controlled on basal insulin plus oral antihyperglycemic drugs (OADs).

RESEARCH DESIGN AND METHODS
In SoliMix, a 26-week, open-label, multicenter study, adults with suboptimally controlled basal insulin–treated type 2 diabetes (HbA1c ≥7.5% and ≤10%) were randomized to once-daily iGlarLixi or twice-daily BIAsp 30. Primary efficacy end points were noninferiority in HbA1c reduction (margin 0.3%) or superiority in body weight change for iGlarLixi versus BIAsp 30.

RESULTS
Both primary efficacy end points were met: after 26 weeks, baseline HbA1c (8.6%) was reduced by 1.3% with iGlarLixi and 1.1% with BIAsp 30, meeting noninferiority (least squares [LS] mean difference −0.2% [97.5% CI −0.4, −0.1]; P &lt; 0.001). iGlarLixi was also superior to BIAsp 30 for body weight change (LS mean difference −1.9 kg [95% CI −2.3, −1.4]) and percentage of participants achieving HbA1c &lt;7% without weight gain and HbA1c &lt;7% without weight gain and without hypoglycemia (all P &lt; 0.001). iGlarLixi was also superior versus BIAsp 30 for HbA1c reduction (P &lt; 0.001). Incidence and rates of American Diabetes Association level 1 and 2 hypoglycemia were lower with iGlarLixi versus BIAsp 30.

CONCLUSIONS
Once-daily iGlarLixi provided better glycemic control with weight benefit and less hypoglycemia than twice-daily premix BIAsp 30. iGlarLixi is a more efficacious, simpler, and well-tolerated alternative to premix BIAsp 30 in suboptimally controlled type 2 diabetes requiring treatment beyond basal insulin plus OAD therapy.

Video 1
In This Issue
Authors: Briggs David 
Published: June 2021

In this issue, we commence with a commentary from the Federal President of ACHSM Dr Neale Fong that goes to contemporary issues around leadership and management in the context of the College and then goes on to address the concepts of credentialing and certification and their importance in the profession of health management. The following 12 research articles and the 4 review articles have been published. Welcome to reading!
MAX BLECHER’S CENTRAL EUROPEAN AFFINITIES
Authors: GLĂVAN Gabriela 
Published: June 2021

Max Blecher’s Central European Affinities. Max Blecher’s connections with the Central European literary imaginary, which scholars have established through readings that place Blecher in the proximity of authors such as Bruno Schulz or Franz Kafka, could be revisited not only comparatively, but also by tackling some key issues in his work and biography that may confirm the writer’s belonging to this vast intellectual territory. Provincial spaces, marginality, uncertainties regarding identity, existential confusion, immaturity, the pervasiveness of objects and of the artificial, they all reveal a perspective upon literature that may function, in the absence of a geographical belonging, as a bridge and connection between worlds that mirror each other’s essence and difference.
REZUMAT. Max Blecher – afinități central-europene. Conectarea lui Max Blecher la imaginarul central-european, consolidată critic prin asocieri cu Franz Kafka sau Bruno Schulz, poate fi rediscutată nu doar din perspectivă comparativă, ci și prin explorarea unor aspecte ce-i pot justifica direct apartenența la acest vast teritoriu intelectual. Provincia, marginalitatea, incertitudinea identității, confuzia, imaturitatea, invazia obiectelor și a artificialului revelează o viziune literară ce poate funcționa, în absența unei apartenențe geografice, ca punte și conector între lumi ce-și expun în oglindă specificul și diferența.
Cuvinte-cheie: literatura central-europeană, identitatea, provincia, perifericul, evreitatea
MODIFICATION VERSUS COMPLEMENTATION IN THE STRUCTURE OF ENGLISH NOUN PHRASES
Authors: PREDA Alina 
Published: June 2021

Modification versus Complementation in the Structure of English Noun Phrases. Apart from its head, the core element around which all the other phrasal constituents cluster, the noun phrase may contain dependent elements effecting determination (which poses few taxonomical issues), modification or complementation (two functions notoriously difficult to demarcate). This article outlines the inconsistent ways in which reference grammars make the distinction between modification and complementation in the structure of English noun phrases, and offers a more unified approach aimed to solve the terminological quandary.
REZUMAT. Structura grupului nominal din limba engleză. Se remarcă, ȋn structura sintagmelor nominale din limba engleză, constituenți greu de clasificat ca realizând complementarea sau tipul de determinare cunoscut ȋn engleză drept modification (ȋn contrast cu cel numit determination, foarte ușor de identificat), ceea ce a dat naștere unor analize contradictorii ȋn literatura de specialitate. Pornind de la dificultăţile în analiză create de similaritatea anumitor elemente direct dependente sintactic de termenul nominal cu rol de centru al respectivului grup, acest articol examinează structura sintagmelor nominale aşa cum este ea prezentată în gramatica practică a limbii engleze, prin analiza comparativă a diferitelor publicaţii de acest gen.
Cuvinte-cheie: complementare, determinare, predeterminare, postdeterminare, complement, sintagme nominale
KEWIRAUSAHAAN DAN GENDER: SEBUAH STUDI DARI PERSPEKTIF SOSIAL BUDAYA DAN PSIKOLOGI
Authors: Afrianty Tri Wulida 
Published: June 2021

This study aims to explore the driving factors and challenges associated with women entrepreneurship in Indonesia, specifically in East Java. This study examines these factors from the socio-cultural (including the possible role of religion) and psychology perspectives. Theoretical sampling and maximum variation sampling techniques are used to determine the research sample (participant / informant). A total of 25 female entrepreneurs who own micro, small and medium businesses/ MSMEs in East Java participated in this research. The results of this study show that family factors and religious beliefs possessed by informants greatly influence their decision to become an entrepreneur. Moreover, this study also shows that the determination, the courage to take risks, the ability to find opportunities, be innovative, believe in one's own abilities and persuasive abilities are several characters that are believed to be crucial as a provision to be an entrepreneur. In addition, the results of this study are in line with the Sociological Theory of Entrepreneurship, the Feminist Theory of Entrepreneurship, and the Psychological Theory of Entrepreneurship. Penelitian ini bertujuan untuk mengeksplorasi faktor-faktor pendorong serta tantangan yang terkait dengan kewirausahaan wanita di Indonesia, khususnya di daerah Jawa Timur. Penelitian ini menelaah faktor-faktor tersebut dari perspektif sosial budaya (termasuk kemungkinan peran agama) dan psikologi. Teknik theoretical sampling dan maximum variation sampling dipergunakan untuk menetapkan sampel (partisipan/informan) penelitian. Sejumlah 25 orang wirausaha wanita pemilik usaha berskala mikro, kecil, dan menengah (UMKM) di daerah Jawa Timur dijadikan partisipan. Hasil penelitian ini menunjukkan bahwa faktor keluarga serta ajaran agama yang dimiliki oleh informan sangat mempengaruhi keputusannya untuk berwirausaha. Penelitian ini juga menunjukkan bahwa keteguhan sikap, berani mengambil resiko, kemampuan untuk membaca peluang, inovatif, percaya pada kemampuan diri sendiri serta kemampuan persuasif merupakan hal yang diyakini penting sebagai bekal yang harus dimiliki untuk menjadi seorang wirausaha. Hasil penelitian ini mendukung teori kewirausahaan Sociological, Feminist, dan Psychological.