bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intelligent Fracture Diagnostic Procedure Using Smart Microchip Proppants Data
Authors: Van Pham Vuong , Kalantari Dahaghi Amirmasoud , Negahban Shahin , Fincham William , Babakhani Aydin 
Published: December 2021

Abstract
Unconventional oil and gas reservoir development requires an understanding of the geometry and complexity of hydraulic fractures. The current categories of fracture diagnostic approaches include methods for near-wellbore (production and temperature logs, tracers, borehole imaging) and far-field techniques (micro-seismic fracture mapping). These techniques provide an indirect and/or interpreted fracture geometry. Therefore, none of these methods consistently provides a fully detailed and accurate description of the character of created hydraulic fractures. This study proposes a novel approach that uses direct data from the injected fine size and battery-less Smart MicroChip Proppants (SMPs) to map the fracture geometry. This novel approach enables direct, fast, and smart of the received high-resolution geo-sensor data from the SMPs collected in high pressure and high-temperature environment and maps the fracture network using the proposed Intelligent and Integrated Fracture Diagnostic Platform (IFDP), which is a closed-loop architecture and is based on multi-dimensional projection, unsupervised clustering, and surface reconstruction. Affine transformation and a shallow ANN are integrated to control the stochasticity of clustering. IFDP proves its efficacy in fracture diagnostics for 3 in-house design synthetic fracture networks, with 100% consistency, rated "fairly satisfied" to "highly satisfied" in prediction capability, and between 85-100% in execution robustness. The integration of the couple affine transformation-ANN increases the performance of unsupervised clustering in IFDP.
Production and Quantification of Virulence Factors in Malassezia Species
Authors: Hadrich Inès , Neji Sourour , Trablesi Houaida , Ilahi Amin , Chouaki Taieb , Ranque Stéphane , Makni Fattouma , Ayadi Ali 
Published: December 2021

Abstract

A total of 77 strains of Malassezia were included in this study. Biofilm production and hydrolytic enzymes were studied by using specific solid media. Real-time Reverse Transcriptase qPCR method was applied to determine overexpression of genes encoding extracellular enzyme.
All included Malassezia species produced biofilms. No statistical significant difference was observed between biofilm formation of the Malassezia species (P = 0.567) . All Malassezia species produced lipase and 95% of M. globosa showed a strong enzymatic activity (Pz=0.55 ± 0.02). Statistical significant difference was observed between the mean keratinase indices of M. slooffiae and the others Malassezia species ( P = 0.005).
The overexpression of one or more genes was observed in 100% of strains isolated from patients with folliculitis, in 87.5% for pityriasis versicolor isolates and in 57.14% for the control group isolates. A statistical significant difference of the lipase gene expression ( P = 0.072) was associated with the strains collected from patients with folliculitis vs group control.
This investigation provides more information about the frequency of the production of the major enzymes considered to be virulence factors of Malassezia species. Interestingly, the overexpression of one or more genes was observed in strains isolated from patients with Malassezia disorder.
A Rapid Assessment of Knowledge, Attitudes and Practices of Mothers Admitted with Diarrhoea Suffering Children in West Urban Region of Unguja-Zanzibar
Authors: Kheir Kheir M. , Mbwele Bernard , Omary Khadija , Damas Modester , Nmakinga Lucy 
Published: December 2021

Abstract
BackgroundThe knowledge, attitude and health practices of the mothers directly reflect on the health and vitality of the child in most of diarrhoea affected communities. The aim of the study was to determine the knowledge, attitude and practice of mothers and caregivers (house girls) towards diarrhoeal disease among children under-five in Unguja, Zanzibar Tanzania. MethodsA quantitative cross-sectional study using a rapid appraisal technique to assess the knowledge, attitudes and practice of mothers and caregivers admitted with children with diarrhoeal diseases was conducted in 23 hospitals of west urban region of Unguja, Zanzibar. ResultsA total of 102 mothers and caregivers were studied. From the respondents 97 (95%) had satisfactory level of knowledge on diarrhoea while 5 (5%) had unsatisfactory knowledge. A total of 52 (51%) rejected the use of Oral Rehydration Solution (ORS) at home due to taste and smell and 50 (49%) agreed its use. A total of 55 (54%) children were served by caregivers. Collectively mothers and caregivers were asked for their practice of drinking treated or boiling water where 47 (46%) reported not to practice. A total of 48 (47%) respondents reported hand washing after helping children with defecation while only 19 (19%) respondents reported washing hands before preparing food. ConclusionLimited use of water sanitation and hygiene (WASH) practices was observed among mothers and caregivers in the prevention and management of under-five children with diarrhoeal disease.
Mantle wedge oxidation due to sediment-infiltrated deserpentinisation
Authors: Padrón-navarta José Alberto , Sánchez-Vizcaíno Vicente López , Menzel Manuel , Gómez-Pugnaire María Teresa , Garrido Carlos 
Published: December 2021

Abstract
The Earth's mantle is oxygen-breathing through the ¬sink of oxidised tectonic plates at convergent margins. Ocean floor serpentinisation increases the bulk oxidation state of iron relative to dry oceanic mantle and results in a variable intake of other redox-sensitive elements such as sulphur. The reversibility of seafloor oxidation in subduction zones during high-pressure dehydration of serpentinite (“deserpentinisation”) at subarc depths and the capacity of the resulting fluids to oxidise the mantle source of arc basalts are highly contested. Thermodynamic modelling, experiments, and metaperidotite study in exhumed high-pressure terrains result in differing estimates of the redox state of deserpentinisation fluids, ranging from low to highly oxidant. Here we show that although intrinsic deserpentinisation fluids are highly oxidant, the infiltration of small fractions of external fluids equilibrated with metasedimentary rocks strongly modulates their redox state and oxidation-reduction capacity explaining the observed discrepancies in their redox state. Infiltration of fluids equilibrated with graphite-bearing sediments reduces the oxidant, intrinsic deserpentinisation fluids to oxygen fugacities similar to those observed in most graphite-furnace experiments and natural metaperidotites. However, infiltration of CO2-bearing fluids equilibrated with modern GLOSS generates sulphate-rich, highly oxidising deserpentinisation fluids. We show that such GLOSS-infiltrated deserpentinisation fluids can effectively oxidise the mantle wedge of cold to hot subduction zones potentially accounting for the presumed oxidised nature of the source of arc basalts.
Optical cavity-referenced terahertz synthesizer with 15-digit short-term stability
Authors: Shin Dong-Chel , Kim Byung Soo , Jang Heesuk , Kim Young-Jin , Kim Seung-Woo 
Published: December 2021

Abstract
Stable terahertz sources are required to advance high precision terahertz applications such as molecular spectroscopy, terahertz radars, and wireless communications. Here, we demonstrate a photonic scheme of terahertz synthesis using an optical comb in stabilization to an ultra-low expansion optical cavity offering a 15-digit accuracy. By heterodyne photomixing of comb lines, terahertz frequencies of 0.10 – 1.10 THz are synthesized with a 2-mHz linewidth and a fractional instability of 3.26×10-15 at 1.3-s integration. Compared to other state-of-the-art counterparts, our terahertz synthesizer offers a fine frequency tuning capability in steps of 100 MHz and an extremely low level of phase noise below -70 dBc/Hz even at 1 Hz offset. Such unprecedented performance is expected to drastically improve the signal-to-noise ratio of terahertz radars, the resolving power of terahertz molecular spectroscopy, and the transmission capacity of wireless communications.
Effects of Interleukin-1β on Long Noncoding RNA and mRNA Expression Profiles of Human Synovial Fluid-derived Mesenchymal Stem Cells
Authors: Sun Yang-peng , Lu Yun-yang , Chen Jianyu , Bao Jia-hao , Zhang Hong , Sun Jia-dong , Liao Wen-ting 
Published: December 2021

Abstract
Synovial fluid-derived mesenchymal stem cells (SFMSCs) play important regulatory roles in the physiological balance of the temporomandibular joint. Interleukin (IL)-1β regulates the biological behavior of SFMSCs; however, the effects of IL-1β on long noncoding RNA (lncRNA) and mRNA expression in SFMSCs in the temporomandibular joint are unclear. Here, we evaluated the lncRNA and mRNA expression profiles of IL-1β-stimulated SFMSCs. Using microarrays, we identified 286 lncRNAs (222 upregulated, 64 downregulated) and 304 mRNAs (242 upregulated, 62 downregulated) that were differentially expressed after treatment with IL-1β (fold change ≥ 2, P < 0.05). Kyoto Encyclopedia of Genes and Genomes pathway analysis found that one of the most significantly enriched pathways was the NF-κB pathway. Five paired antisense lncRNAs and mRNAs, eight paired enhancer lncRNAs and mRNAs, and nine paired long intergenic noncoding RNAs and mRNAs were predicted to be co-expressed. A network constructed by the top 30 k-score genes was visualized and evaluated. We found a co-expression relationship between ENST00000427824 and ENST00000307407 and between LOC541472 and IL6, which are related to NF-κB pathway activation. Overall, our results provide important insights into changes in lncRNA and mRNA expression in IL-1β-stimulated SFMSCs, which can facilitate the identification of potential therapeutic targets.
Multi-year El Niño events tied to the North Pacific Oscillation
Authors: Ding Ruiqiang , TSENG YU-HENG , Lorenzo Emanuele Di , Shi Liang , Li Jianping , Yu Jin-Yi , Wang Chunzai , Sun Cheng , Luo Jing-Jia , Ha Kyung-Ja , Hu Zeng-Zhen , Li Feifei 
Published: December 2021

Abstract
Multi-year El Niño events induce severe and persistent floods and droughts worldwide, with significant socioeconomic impacts, but the causes of their long-lasting behaviors are still not fully understood. Here we present a two-way feedback mechanism between the tropics and extratropics to argue that extratropical atmospheric variability associated with the North Pacific Oscillation (NPO) is a key source of multi-year El Niño events. The NPO during boreal winter can trigger a Central Pacific (CP) El Niño during the subsequent winter, which excites atmospheric teleconnections to the extratropics that project onto the NPO variability, then re-triggers another El Niño event in the following winter, finally resulting in persistent El Niño-like states. Model experiments, with the NPO forcing assimilated to constrain atmospheric circulation, replicate the observed connection between NPO forcing and the occurrence of multi-year El Niño events. Future projections of Coupled Model Intercomparison Project phases 5 and 6 (CMIP5 and CMIP6) models demonstrate that if the projected NPO variability becomes enhanced under future anthropogenic forcing, then more frequent multi-year El Niño events should be expected. We conclude that properly accounting for the effects of the NPO on the evolution of El Niño events may improve multi-year El Niño prediction and projection.
High-Hydrophilic and Antifouling Poly (Vinylidene Fluoride) Composite Membranes via in Situ Mosaic- Assembled Nanocrystalline Cellulose and g-C3N4
Authors: Li Hongbin , liu chao , Guo Yongqiang , Gao Shuzhen 
Published: December 2021

Abstract
Developing an antifouling and stable separation poly (vinylidene fluoride) (PVDF) membrane for water treatment is of great significance but challenging due to the limitations of its low surface properties and strong hydrophobicity. In this study, a novel multi-block composite ultrafiltration membrane was developed using the mosaic-assembled doping of pineapple leaf nanocrystalline cellulose and g-C3N4. The effects of adding different components on the PVDF composite membrane properties have been analyzed. The surface chemical composition, surface morphology, crystallinity and thermal stability of the composite membranes were characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), X-ray diffraction (XRD) and thermogravimetric analysis (TGA). Both of the tensile strength and elongation length of the PVDF composite membranes were enhanced due to the addition of pineapple leaf nanocellulose and g-C3N4, and the tensile strength and elongation length of PVDF/PEG/g-C3N4/Pineapple leaf nanocellulose composite membrane can reach 10.61 MPa and 8.85 mm. The porosity of the PVDF composite membranes was 46.6%, respectively. The water flux and flux recovery ratio of PVDF/PEG/g-C3N4/Pineapple leaf nanocellulose also can reach 256.75 L/(m2 ⋅h) and up to 82.1%. All the above experimental data showed that the addition of pineapple leaf nanocellulose and g-C3N4 can greatly improve the performance of the PVDF composite membrane. The prepared modified membrane has potential application value in the field of wastewater separation and treatment.
A Prospective Comparison of 3 Hamstring ACL Fixation Devices - Rigidfix, BioScrew and Intrafix - Randomized Into 4 Groups with a Minimum Follow-Up of 5 Years.
Authors: Metso Leena , Bister Ville , Harilainen Arsi , Sandelin Jerker 
Published: December 2021

Abstract
Background: This is a five years follow-up report of some of the new devices for graft fixation. A two years follow-up data was published previously. As there were no statistically or clinically relevant differences in the results two years postoperatively, we hypothesize that after five years of follow-up there is no difference in the outcome after either cross-pin or absorbable interference screw fixation in ACL (anterior cruciate ligament) reconstruction with hamstring tendon autografts.Methods: 120 patients were randomized into four different groups (30 each) for ACL reconstruction with hamstring tendons: group I femoral Rigidfix cross-pin and Intrafix tibial extension sheath with a tapered expansion screw; group II Rigidfix femoral and BioScrew interference screw tibial fixation; group III BioScrew femoral and Intrafix tibial fixation; group IV BioScrew fixation into both tunnels. The evaluation methods were clinical examination, knee scores, and instrumented laxity measurements. Results: In this 5 years follow-up there were 102/120 (85%) patients available, but only 77 (64,2%) attended the clinical examinations. No significant difference between the groups in the clinical results was detected. There was a significant difference in additional procedures between the 2 and 5 years follow-up, group I had six additional procedures between the 2 and 5 years follow-up (P=.041). Conclusion: There was a statistically significant difference in the additional procedures, most in group I (six). None of these procedures found problems with the ACL graft. Other statistically or clinically significant differences in the 5 years follow-up results were not found. Study design: Randomized controlled clinical trial; Level of evidence, 1.Trial registration: ISRCTN registry with study ID ISRCTN34011837. Retrospectively registered 17.4.2020.
Seroprevalence of SARS-CoV-2 IgG Antibodies After the Second BNT162b2 mRNA Vaccine in Japanese Kidney Transplant Recipients
Authors: Hamaya Tomoko , Hatakeyama Shingo , Yoneyama Tohru , Tobisawa Yuki , Kodama Hirotake , Fujita Takeshi , Murakami Reiichi , Fujita Naoki , Okamoto Teppei , Yamamoto Hayato , Yoneyama Takahiro , Hashimoto Yasuhiro , Saitoh Hisao , Narumi Shunji , Tomita Hirofumi , Ohyama Chikara 
Published: December 2021

Abstract
We aimed to evaluate the rate of anti–SARS-CoV-2 IgG seropositivity and investigated factors associated with seropositivity after the second SARS-CoV-2 mRNA vaccination in kidney transplant (KT) recipients. This retrospective study conducted between June 2021 and November 2021 included 106 KT recipients and 127 healthy controls who received the second dose of the BNT162b2 mRNA vaccine at least seven days before the measurement of antibody titers. The titers of immunoglobulin G (IgG) antibodies against the receptor-binding domain of SARS-CoV-2 spike (S) protein were determined. Seropositivity was defined as an anti–SARS-CoV-2 IgG level of ≥15 units/mL, which was considered as the presence of sufficient neutralizing antibodies. The median ages and the seroprevalence rates of the healthy controls and KT recipients were 68 and 56 years and 98% and 22%, respectively. Univariate logistic regression analysis revealed that age >53 years, rituximab use, mycophenolate mofetil use, and KT vintage <7 years were negatively associated with anti–SARS-CoV-2 IgG seropositivity in KT recipients. Humoral response after the second BNT162b2 mRNA vaccine was greatly hindered by immunosuppression therapy in KT recipients. Older age, rituximab use, mycophenolate mofetil use, and KT vintage may play key roles in seroconversion.
Superconductivity above 200K Observed in Superhydrides of Calcium
Authors: Li Zhiwen , He Xin , Zhang Changling , Zhang Sijia , Jia Yating , Feng Shaomin , Lu Ke , WANG Xiancheng , Zhao Jianfa , Long Youwen , Yu Richeng , Wang Luhong , Ye Meiyan , Zhang Zhanshuo , Prakapenka Vitali , Chariton Stella , Liu Haozhe , Jin Changqing 
Published: December 2021

Abstract
Searching for superconductivity with Tc near room temperature is of great interest both for fundamental science & potential applications. Here we report the experimental discovery of superconductivity with maximum critical temperature(Tc) above 210 K in calcium superhydrides, the third type hydride experimentally showing superconductivity above 200K in addition to sulfur hydride & rare earth hydride system. The materials are synthesized at the synergetic conditions of 160~190 GPa and ~2000K using diamond anvil cell combined with in-situ laser heating technique. The superconductivity was studied through in situ high pressure resistance measurements in applied magnetic field for the sample quenched from high temperature while maintained at the synthesized pressure. The upper critical field was estimated to be ~268T while the GL coherent length is ~11 Å. The in situ x ray diffractions with synchrotron suggest that the synthesized calcium hydrides are primarily composed of CaH6 while there also exist other calcium hydrids with different hydrogen.
Impact of Commercial Decision Making in the Cost at the Pre-Tendering Stage
Authors: Ganesh Ramya , Anjum Taqdees 
Published: December 2021

Abstract
The Indian construction industry has the cognitive frame of operating in the cost-based approach rather than the value-based approach, and the project process and strategies are framed in such a manner to increase the profitability of the project by the organization. Nevertheless, the profitability margin of the construction project is very comparatively low compared to the other Industrial sectors. There is much reason for not attaining a higher profitability margin in the construction sector. Some of the reasons are the low innovative business plan, ineffective data-driven decision-making, ineffective management of the transaction, and construction risks.The responsibilities of increasing profitability and managing the transactional flow in the project are given to the commercial manager. The roles and responsibilities of the commercial manager vary globally. The quantity surveyor's job role further enhanced the commercial manager, where the latter can take the commercial decisions about the project.This research paper's primary outcome is the framework model for making effective decisions by the commercial manager, which increases the project's profitability. The systematic decisions, which are made in the projects by the commercial manager are studied. Considering the external factors like the COVID-19 outbreak, market condition, and existing factors affecting the decision-making process, the tools and techniques for making efficient decisions in the construction project are suggested. The synergies between these tools and techniques are studied, and a decision-making model is framed to reduce the cost and time overrun, and the benefits associated with implementing the model in the project are detailed.
Ultrasensitive and rapid identification of ESRI developer- and piperacillin/tazobactam-resistant Escherichia coli by the MALDIpiptaz test
Authors: Rodríguez-Villodres Ángel , Benítez Lydia Gálvez , Arroyo Manuel , Méndez Gema , Mancera Luis , Domínguez Andrea Vila , Lepe José , Smani Younes 
Published: December 2021

Abstract

The excessive use of piperacillin/tazobactam (P/T) has promoted the emergence of P/T-resistant Enterobacterales. We reported that in Escherichia coli, P/T contributes to the development of extended-spectrum resistance to β-lactam/β-lactamase inhibitor (BL/BLI) (ESRI) in isolates that are P/T susceptible but have low-level resistance to BL/BLI. Currently, the detection of P/T resistance relying on conventional methods is time-consuming. To overcome this issue, we developed a cost-effective test based on MALDI-MS technology, called MALDIpiptaz, which aims to detect P/T resistance and ESRI developers in E. coli. We used automated Clover MS Data Analysis software to analyse the protein profile spectra obtained by MALDI-MS from a collection of 248 E. coli isolates (91 P/T-resistant, 81 ESRI developers and 76 P/T-susceptible). This software allowed to preprocess all the spectra to build different peak matrices that were analysed by machine learning algorithms. We demonstrated that MALDIpiptaz can efficiently and rapidly (15 min) discriminate between P/T-resistant, ESRI developer and P/T-susceptible isolates and allowed the correct classification between ESRI developers from their isogenic resistance to P/T. The combination of excellent performance and cost-effectiveness are all desirable attributes, allowing the MALDIpiptaz test to be a useful tool for the rapid determination of P/T resistance in clinically relevant gram-negative bacteria.
Fetal Aberrant Right Subclavian Artery: Associated Anomalies, Genetic Etiology, and Postnatal Outcomes in a Retrospective Cohort Study
Authors: Cai Meiying , Fan Xiangqun , Chen Xuemei , Xu Shiyi , Fu Xiangguo , Xu Liangpu , Huang Hailong , Lin Na 
Published: December 2021

Abstract
Aberrant right subclavian artery (ARSA) is becoming more common in fetuses. However, there are relatively few studies on the genetic etiology of ARSA. We performed genetic analysis on fetuses with ARSA and followed up the pregnancy outcome to evaluate the prognosis of the fetuses, providing information for prenatal and eugenics consultations. A retrospective study was conducted on 112 pregnant women with fetuses diagnosed with ARSA from December 2016 to February 2021. Karyotype analysis and single-nucleotide polymorphism array (SNP-array) were performed in 112 fetuses. The 112 fetuses were divided into two groups: ARSA group, 48 (42.9%) and ARSA with other ultrasound abnormalities group, 64 (57.1%) cases. The total rate of pathogenic copy number variation (CNV) was 7.1% (8/112) using karyotype analysis (3/8) and SNP-array (5/8). The rate of pathogenic CNV in isolated ARSA and ARSA combined with other ultrasound abnormalities were 4.2% (2/48) and 9.4% (6/64), respectively. There was no significant difference between the two groups (P=0.463). The results of genetic analysis influence parents' decision to terminate the pregnancy. During follow-up, fetuses with ARSA without pathogenic CNV were found to have normal growth and development after birth. Therefore, prenatal genetic counseling and SNP-array should be recommended to better assess fetal prognosis.