bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERANCANGAN HEXACOPTER UNTUK MENGAMBIL BARANG MENGGUNAKAN SENSOR LIDAR LITE V3
Authors: Hasan Geri Asbi , Akbar Son Ali 
Published: August 2021

Pada Penelitian ini merancang sebuah hexacopter (Drone) yang dapat mengambil barang dengan menggunakan sensor Lidar Lite v3 yang berfungsi untuk menambah tingkat keakuratan dalam mengukur jarak objek sedangkan sebagai pusat kendali pada hexacopter menggunakan flight controller Pixhawk. Hexacopter yang dirancang akan mengambil sebuah barang menggunakan sistem mekanik gripper dengan penggerak yaitu motor servo karena melihat spesifikasi dari motor servo lebih dapat menangani arus yang tinggi atau beban berat, Motor servo dikendalikan dengan memberikan sinyal modulasi lebar pulsa melalui kabel kontrol. hexacopter ini menggambil barang secara semi otomatis dengan acuan jarak pada pembacaan sensor Lidar Lite v3. Perancangan pada hexacopter untuk mengambil barang berupa survival kits ini bertujuan untuk mengurangi tugas manusia dalam pengiriman cepat barang menggunakan jalur udara. Dari hasil pengujian yang telah dilakukan dapat disimpulkan bahwa hexacopter (drone) ini dapat berjalan dengan baik pada saat mengambil barang tersebut dengan mekanik gripper dan motor servo sebagai penggerak.Kesimpulan dari alat yang dirancang sebagai media angkut barang berupa survival kits melalui jalur udara, mekanik penggerak gripper dapat diaplikasikan menggunakan beberapa motor servo.
ANALISIS PENGARUH AIR GAP (CELAH UDARA) TERHADAP UNJUK KERJA GENERATOR AXIAL FLUX DOUBLE SIDE ROTOR 1 FASA DENGAN KUTUB BERLAWANAN (N-S)
Authors: Khikmah Qoidatul , Hadi Widyono , Cahyadi Widya 
Published: August 2021

Energi terbarukan skala kecil sebagai sumber energi listrik alternatif hanya mampu membangkitkan energi mekanik yang rendah. Penggunaannya membutuhkan generator jenis axial flux permanent magnet (AFPM) yang dapat bekerja pada putaran rendah. Beberapa studi telah dilakukan tentang generator axial flux seperti dalam rancang bangun dan penelitian beberapa parameter yang mempengaruhi performa generator. Celah udara merupakan parameter penting yang dapat mempengaruhi kinerja generator. Penelitian ini dilakukan dengan memberikan variasi celah udara sebesar 8 mm, 9 mm, dan 10 mm pada generator axial flux konstruksi double side rotor untuk membangkitkan AC 1 fasa menggunakan magnet permanen Neodymium Iron Boron (NdFeB) dan disusun secara kutub berlawanan (N-S). Dengan memberikan beban 3 LED terhubung seri pada kecepatan putar 3000 rpm, pengujian saat celah udara 8 mm diperoleh frekuensi sebesar 450.4 Hz, tegangan output 7.468 V, arus output 14.961 mA, daya output W dan torsi rotor sebesar Nm. Pada pengujian celah udara 9 mm diperoleh frekuensi 450,4 Hz, tegangan output 7.279 V, arus output 7.444 mA, daya output W dan torsi rotor sebesar Nm. Sedangkan pengujian celah udara 10 mm diperoleh frekuensi 450.4 Hz, tegangan output 6.826 V, arus output 1.298 mA, daya output W dan torsi rotor sebesar Nm.
Effects of miR-185-5p on replication of hepatitis C virus
Authors: Huang Wei , Song Lingyan , Zhang Jingyan , Yan Xueqiang , Yan Hui 
Published: August 2021

Abstract
This article was designed to explore the effects and mechanisms of miR-185-5p on the replication of hepatitis C virus (HCV). Quantitative reverse transcription PCR (qRT-PCR) was performed for detecting the abundance of miR-185-5p and HCV RNA in HCV-infected primary hepatocytes and Huh7.5 cells. Dual-luciferase reporter gene assay was used for exploring the interaction between miR-185-5p and GALNT8. Western blot analyzed protein expression of GALNT8, NS3, and NS5A. miR-185-5p was remarkably downregulated in HCV-infected primary hepatocytes and Huh7.5 cells. miR-185-5p upregulation inhibited HCV RNA expression, while its inhibition promoted HCV replication. miR-185-5p induced accumulation of NS3 and NS5A in the cells. Dual-luciferase reporter gene assay verified the targeted relationship between miR-185-5p and GALNT8. In addition, the effects of overexpressing or knocking down miR-185-5p on HCV replication could be correspondingly eliminated by the overexpression or knockdown of GALNT8. miR-185-5p may target GALNT8 in JFH1-infected Huh7.5 cells and then inhibit HCV replication. miR-185-5p may be a potential target for treating HCV.
Perceived emotional and informational support for cancer: Patients’ perspectives on interpersonal versus media sources
Authors: Bol Nadine , Rising Camella J. , Weert Julia C. M. van 
Published: August 2021

Abstract
This study examined cancer patients’ (N = 355, 65.4 % female, Mage
= 54.35, SDage
= 11.25) perceived emotional and informational support from a variety of interpersonal and media sources. We recruited patients from cancer patient association websites and online cancer forums and asked them to report to what extent they received support from interpersonal and media sources. Patients rated professional sources (e. g., oncologists) and personal sources (e. g., family) as nearly equal sources of emotional support; however, professional sources were rated as significantly greater sources of informational support. Although family and oncologists were the most mentioned interpersonal sources of support, they were also the most mentioned disappointing sources. Of the media sources, online interaction sources (e. g., online support groups) were rated as nearly equivalent sources of emotional support as interpersonal sources. That patients perceived emotional support, not only informational support, from various media sources is promising since interpersonal sources can be disappointing to some patients.
A generalization of Sims’ conjecture for finite primitive groups and two point stabilizers in primitive groups
Authors: Spiga Pablo 
Published: August 2021

AbstractIn this paper, we propose a refinement of Sims’ conjecture concerning the cardinality of the point stabilizers in finite primitive groups, and we make some progress towards this refinement. In this process, when dealing with primitive groups of diagonal type, we construct a finite primitive group 𝐺 on Ω and two distinct pointsα,β∈Ω\alpha,\beta\in\OmegawithGα⁢β⊴GαG_{\alpha\beta}\unlhd G_{\alpha}andGα⁢β≠1G_{\alpha\beta}\neq 1, whereGαG_{\alpha}is the stabilizer of 𝛼 in 𝐺 andGα⁢βG_{\alpha\beta}is the stabilizer of 𝛼 and 𝛽 in 𝐺. In particular, this example gives an answer to a question raised independently by Cameron and by Fomin in the Kourovka Notebook.
The Mechanisms of Neolithisation of Western Europe: Beyond a South/North Approach
Authors: Hamon Caroline , Manen Claire 
Published: August 2021

AbstractUp until now, the neolithisation of Western Europe during the sixth millennium BCE has mainly been approached through the characterisation of its diffusion vectors (cultural vs demic diffusion) and the emergence of technoeconomic innovations (rhythms, scenarios, and transmission). Traditionally, two primary routes of agricultural diffusion are distinguished: one extending along the Danube river corridor to the Atlantic coast (Linearbandkeramik) and the other along the Mediterranean coastal zone (Impressed Ware). To move beyond this dichotomy, this article proposes a first attempt at an integrated approach to the mechanisms of neolithisation in Western Europe, one of the few territories where it is possible, and therefore necessary, to investigate the processes that are common to both of these principal neolithisation complexes. The most widely held vision, inherited from the 1980s, of a European Neolithic that developed from east to west following a regular rhythm has progressively been replaced by a more complex model of diffusion characterised by arrhythmia and cultural reconfigurations. Despite having different origins and trajectories, the expansion of the first farmers was made possible by a number of common mechanisms.Impresso-CardialandLinearbandkeramiksocieties faced similar constraints, especially with regard to ensuring the stability of their social and economic models, while minimising the risks inherent to the colonisation of new territories. Three main mechanisms would have structured the first neolithisation phases of both spheres: a strong mobility of populations regulated to varying degrees by social rules, a strong solidarity expressed at multiple levels of interactions within each sphere, and, finally, the existence of syncretism and cultural recompositions including close and long-distance relations.
Die Mittelstandspolitik nach Corona – für eine nachhaltige Zukunft
Authors: Welter Friederike , Levering Britta 
Published: August 2021

Zusammenfassung
Corona-Pandemie, Digitalisierung, Green Deal – die mittelständischen Unternehmen stehen in den kommenden Jahren neben ihren branchen- und größenspezifischen Aufgaben vor großen Herausforderungen. Diese können sie nur bewältigen, wenn die Politik ihnen einen verlässlichen Rahmen bietet, innerhalb dessen sie wirtschaftlich agieren können. Friederike Welter und Britta Levering zeigen in ihrem Beitrag, worauf die Mittelstandspolitik in Gesetzgebung und Gestaltung von Unterstützungsmaßnahmen aus Sicht der Mittelstandsforschung achten sollte, damit die Wettbewerbs- und Innovationsfähigkeit der mittelständischen Unternehmen nachhaltig gestärkt wird.
Estradiol-driven metabolism in transwomen associates with reduced circulating extracellular vesicle microRNA-224/452
Authors: Florijn Barend W , Duijs Jacques M G J , Klaver Maartje , Kuipers Eline N , Kooijman Sander , Prins Jurrien , Zhang Huayu , Sips Hetty C M , Stam Wendy , Hanegraaf Maaike , Limpens Ronald W A L , Nieuwland Rienk , van Rijn Bas B , Rabelink Ton J , Rensen Patrick C N , den Heijer Martin , Bijkerk Roel , van Zonneveld Anton Jan 
Published: August 2021

Objective
Sex steroid hormones like estrogens have a key role in the regulation of energy homeostasis and metabolism. In transwomen, gender-affirming hormone therapy like estradiol (in combination with antiandrogenic compounds) could affect metabolism as well. Given that the underlying pathophysiological mechanisms are not fully understood, this study assessed circulating estradiol-driven microRNAs (miRs) in transwomen and their regulation of genes involved in metabolism in mice.

Methods
Following plasma miR-sequencing (seq) in a transwomen discovery (n = 20) and validation cohort (n = 30), we identified miR-224 and miR-452. Subsequent systemic silencing of these miRs in male C57Bl/6 J mice (n = 10) was followed by RNA-seq-based gene expression analysis of brown and white adipose tissue in conjunction with mechanistic studies in cultured adipocytes.

Results
Estradiol in transwomen lowered plasma miR-224 and -452 carried in extracellular vesicles (EVs) while their systemic silencing in mice and cultured adipocytes increased lipogenesis (white adipose) but reduced glucose uptake and mitochondrial respiration (brown adipose). In white and brown adipose tissue, differentially expressed (miR target) genes are associated with lipogenesis (white adipose) and mitochondrial respiration and glucose uptake (brown adipose).

Conclusion
This study identified an estradiol-drive post-transcriptional network that could potentially offer a mechanistic understanding of metabolism following gender-affirming estradiol therapy.
Reducing Chest Radiographs in Bronchiolitis Through High-Reliability Interventions
Authors: Frazier S Barron , Walls Claci , Jain Sweeti , Plemmons Gregory , Johnson David P. 
Published: August 2021

BACKGROUND AND OBJECTIVES
Bronchiolitis is a leading cause of pediatric hospitalization in the United States, resulting in significant morbidity and health care resource use. Despite American Academy of Pediatrics recommendations against obtaining chest radiographs (CXRs) for bronchiolitis, variation in care continues. Historically, clinical practice guidelines and educational campaigns have had mixed success in reducing unnecessary CXR use. Our aim was to reduce CXR use for children &lt;2 years with a primary diagnosis of bronchiolitis, regardless of emergency department (ED) disposition or preexisting conditions, from 42.1% to &lt;15% of encounters by March 2020.

METHODS
A multidisciplinary team was created at our institution in 2012 to standardize bronchiolitis care. Given success with higher reliability interventions in asthma, similar interventions affecting workflow were subsequently pursued with bronchiolitis, starting in 2017, by using quality improvement science methods. The primary outcome was the percent of bronchiolitis encounters with a CXR. The balancing measure was return visits within 72 hours to the ED. Statistical process control charts were used to monitor and analyze data obtained from an internally created dashboard.

RESULTS
From 2012 to 2020, our hospital had 12 120 bronchiolitis encounters. Preimplementation baseline revealed a mean of 42.1% for CXR use. Low reliability interventions, like educational campaigns, resulted in unsustained effects on CXR use. Higher reliability interventions were associated with sustained reductions to 23.3% and 18.9% over the last 4 years. There was no change in ED return visits.

CONCLUSIONS
High-reliability workflow redesign was more effective in translating American Academy of Pediatrics recommendations into sustained practice than educational campaigns.
Parents’ Intentions and Perceptions About COVID-19 Vaccination for Their Children: Results From a National Survey
Authors: Szilagyi Peter G. , Shah Megha D. , Delgado Jeanne R. , Thomas Kyla , Vizueta Nathalie , Cui Yan , Vangala Sitaram , Shetgiri Rashmi , Kapteyn Arie 
Published: August 2021

OBJECTIVES
Assess the degree to which US parents are likely to have their children get coronavirus disease 2019 (COVID-19) vaccines and identify parental concerns about the vaccines.

METHODS
In February 2021 to March 2021, we surveyed parent members of a nationally representative probability-based Internet panel of ∼9000 adults regarding their intent to have their children receive a COVID-19 vaccination, perceptions of COVID-19 vaccines for children, and trust in sources of information about COVID-19 vaccines for children. We used descriptive and multivariate analyses to evaluate parent-stated likelihood of having their children get a COVID-19 vaccine and to assess the association between likelihood of child COVID-19 vaccination and child age, parent demographics, and parental perceptions about COVID-19 vaccines.

RESULTS
Altogether, 1745 parents responded (87% of eligible parents, 3759 children). Likelihood of child COVID-19 vaccination was as follows: very likely (28%), somewhat likely (18%), somewhat unlikely (9%), very unlikely (33%), and unsure (12%). The stated likelihood of child vaccination was greater among parents of older children (P &lt; .001) as well as among parents who had a bachelor’s degree or higher education (P &lt; .001), had already received or were likely to receive a COVID-19 vaccine (P &lt; .001), or had Democratic affiliation (P &lt; .001); variations existed by race and ethnicity (P = .04). Parental concerns centered around vaccine safety and side effects. A key trusted source of information about COVID-19 vaccines for children was the child’s doctor.

CONCLUSIONS
Less than one-half of US participants report that they are likely to have their child receive a COVID-19 vaccine. Pediatric health care providers have a major role in promoting and giving COVID-19 vaccination for children.
Buschke-LÃ¶wenstein tumour (BLT)/giant condyloma acuminatum (GCA): An immunopathogenesis insight
Authors: Christopher Paulus Mario , Kosim Hartono , Wijaya Ratna Sari , Suhardi Silvi , Wijayadi Linda Julianti 
Published: August 2021

Buschke LÃ¶wenstein tumor (BLT)/giant condyloma acuminatum is a rare variant ofÂ sexually transmitted infection caused by human papillomavirus (HPV) type 6 and 11. HPV has its viral factors that exist to avoid immune surveillance and control through 1) infecting only the basal layer of the epithelium, 2) downregulation of host immunity, 3) suppression of proinflammatory proteins essential for viral clearance. The incidence of BLT/GCA is estimated to be 0.1% in the general population, with males having 2.7 times increased risk than females.Â BLT/GCA is characterized by verrucous tumor or palpable cauliflower-likemass, exophytic growth, flesh-colored, and uneven surface. The definitive diagnosis of BLT/GCA is typical morphology along with histopathological examination, and/or viral serotyping. Treatment of BLT/GCA requires a multidisciplinary approach, determined based on age, the extent of the lesion, organ involvement, and organ location.
Hygrothermal simulation of building performance: data for Scottish masonry materials
Authors: Banfill P. F. G. 
Published: August 2021

AbstractRetrofitting thermal insulation to solid masonry walls alters their hygrothermal behaviour, which can be modelled by hygrothermal simulation software. However, such software needs values of key material properties to ensure satisfactory results and until now data has not been available for Scottish masonry buildings. This work aims to contribute to a Scotland-specific dataset of material properties for use by designers working on such buildings. Thermal conductivity, water vapour permeability, sorptivity, water absorption coefficient, hygroscopic sorption, density and porosity were all determined experimentally for selected historic and contemporary masonry materials. Within the range of materials tested three groups of materials properties emerge. Natural hydraulic lime mortars, hot-mixed quicklime mortar and earth mortar all show comparatively low density, high porosity, low thermal conductivity, high water vapour permeability and variable but generally high hygroscopic sorption. Craigleith, Hailes and Giffnock sandstones, no longer available but obtained from conservation works on historic buildings, and Locharbriggs and Hazeldean sandstones, obtained from current production, all show intermediate values of these properties. Crathes granodiorite and Scottish whinstone (from current production) show high density, low porosity, high thermal conductivity, low water vapour permeability and low hygroscopic sorption. It is shown that these materials are all relevant to Scottish buildings constructed in traditional masonry and this paper presents the first comprehensive set of hygrothermal property data for them.
Depressão e pandemia: estudo com universitários brasileiros
Authors: Sandin Machado Maria Eduarda , Casiraghi Bruna 
Published: August 2021

A depressão é uma doença incapacitante, crônica e recorrente. Tem como sintomas humor deprimido, desprazer em atividades que antes geravam prazer, perda ou ganho significativo de peso por alteração no apetite, insônia ou hipersonia, falta de energia, sentimento de culpa, dificuldade de se concentrar, baixa autoestima, irritabilidade, ansiedade, e, em casos graves, pode levar ao suicídio. Pode ser classificadas como leve, moderada ou grave de acordo com a intensidade dos síntomas. Essa doença pode piorar em diversos contextos, como em situações de isolamento social, devido ao estresse, ansiedade, falta ou excesso de informação. Os universitários são afetados devido a mudança na rotina e a pressão psicológica. O objetivo do trabalho foi avaliar a quantidade de universitários com sintomas de depressão, comparando cursos da área da saúde com o de outras áreas. A pesquisa teve uma amostra de 210 universitários do estado do Rio de Janeiro, Brasil, sendo 69% do gênero feminino e 31% masculino, com idade média de 23 anos. O questionário foi enviado via rede social contendo: um formulário avaliando dados pessoais e o Inventário de Depressão de Beck (BDI). O BDI mostrou em relação aos universitários que 119 (56.7%) não apresentaram sintomas, 20 (9.5%) apresentaram disforia e 61 (29%) apresentaram sintomas de depressão. onclui-se que os dados indicaram altas taxas de sintomas depressivos entre os universitários estudados e a necessidade de ações de acompanhamento.
DOES EXCESSIVE CONSUMPTION OF FLAXSEED (LINUM USITATISSIMUM L.) CAUSE A LIVER DAMAGE IN RAT MODELS?
Authors: ÖZGÖÇMEN Meltem , YEŞİLOT Şükriye 
Published: August 2021

Natural health products and functional foods are
frequently consumed for the prevention and treatment
of many diseases. Flaxseed is one of the functional foods with anticancer, antiviral, antibacterial and antifungal
properties. In addition to its beneficial effects,
excessive consumption without considering the appropriate
dosage can cause toxic effects. In this study,
it was planned to investigate the effects of different
amounts of flaxseed consumption on rat liver.
Materials and Methods
Rats were randomly divided into four groups with 8
rats in each groups; control group and experimental
groups which given flaxseed for 7 days; 1.4, 2.8 and
5.6 g/kg/day, respectively. At the end of the experiment,
histological, immunohistochemical and biochemical
analyzes were performed on tissue and blood
samples.
Results
Serum AST, ALT and ALP values are significantly higher
in 5.6 g/kg of flaxseed compared to control group
(p values 0.003, 0.012 and 0.009, respectively). Albumin
values were significantly lower in experimental
groups compared to the control group (p
SAĞLIK PROFESYONELLERİNİN SEPSİS HAKKINDAKİ BİLGİ VE ALGILARININ ARAŞTIRILMASI
Authors: ASLANKOÇ Rahime , GÜMRAL Nurhan , ÇEVİK Dilek 
Published: August 2021

Sepsis, konağın enfeksiyonlara karşı düzensiz yanıtı
nedeniyle oluşan, hayatı tehdit eden organ yetmezliğidir.
Sepsisi daha iyi teşhis ve tedavi edebilmek için
sadece tanımlamak ve patofizyolojisini anlamak yeterli
değildir. Aynı zamanda uzmanların sepsisin mevcut
tanı ve tedavisine yönelik algısı ve bu konudaki
tutumu hakkında daha fazla bilgi edinmek de önemlidir.
Bu çalışmada, sağlık profesyonellerinin sepsis
hakkındaki bilgi ve algılarının değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntem
Araştırma bir kamu hastanesinde çalışan, 40 sağlık
profesyonelinin katılımı ile gerçekleşti. Anket formu
literatüre dayalı olarak iki bölümde oluşturuldu. Anket
formları yüz yüze görüşme yöntemi kullanılarak uygulandı.
Bulgular
Çalışmaya katılan 40 hekimin anket formları değerlendirildi.
Katılımcıların %60’ı sepsisin diğer hastalıklara
göre daha ölümcül olduğunu, %65’inin sepsisin
ülkemizin sağlık sistemi üzerine önemli bir yük oluşturduğunu,
%67,5’inin hekimin tedavi edebileceği en
zor koşullar arasında olduğunu ifade ettikleri saptanmıştır.
Hekimlerin %45’i ülkemizde sepsisin kesinlikle
kabul edilmiş bir tanımı olduğunu belirtmiştir. %50’si
sepsis ile ilgili yapılan konsessuslar sonucu oluşturulan
tanımı ifade ederken, %75’i sepsisin sistemik bir
hastalık, ateşin ise en önde gelen belirti olduğu belirttiler.
Ayrıca, %37,5’i sepsisin ortak bir tanımının
olmamasından endişeli olduklarını, %47,5’i sepsisin
ortak bir tanımının olmamasının sepsis tanısının konulamamasına
neden olduğunu, %47,5’i küresel anlamda
sepsis için ortak bir tanımın olmasının tedavide
önemli bir adım olabileceğini ifade ettiler.
Sonuç
Verilerin analizinden üç sonuç çıkarılabilir; hekimlerin
sepsis yönetiminde bazı eksiklikleri olabilir, sepsis tanımlamaları
yetersizdir, ve sepsis sağlık sistemi için
önemli bir problem oluşturmaktadır.