bluuebunny/crossref_metadata_2025_split huggingface dataset:
Por outras e outros Ocañas que merecemos
Authors: Colling Leandro , Cantó Assumpta Sabuco 
Published: May 2021

O texto privilegia uma leitura pouco explorada da obra do artista espanhol José Pérez Ocaña. Ao invés de destacar o artista como um precursor do queer na Espanha, o artigo enfatiza a importância da cultura e da religiosidade da Andaluzia na obra de Ocaña, em especial os seus elementos ritualísticos, por meio dos quais ele questiona as normas de gênero e sexualidade e os próprios ritos religiosos.
Pinturas de Massimo Campigli no MAC USP: Entre arqueologia, memória e modernidade
Authors: Rocco Renata Dias Ferrareto Moura 
Published: May 2021

O artigo trata das seis pinturas do artista alemão naturalizado italiano Massimo Campigli, do acervo do MAC USP. Esse conjunto, ainda não analisado em profundidade pela historiografia da arte no Brasil, será discutido no contexto mais amplo de sua produçãoo artística. Para tanto, recuperamos aspectos da biografia de Campigli e de sua produção e indicamos como as obras chegaram ao acervo do antigo MAM-SP. Por fim, apresentamos a análise plástica e as considerações finais. Para tratar das telas, nos apoiamos em seus escritos autobiográficos, catálogos de exposições, textos críticos, além de informações fornecidas pelo Arquivo da Bienal de São Paulo e pelo Arquivo Campigli. Sobre a incorporação ao museu, nos valemos das pesquisas da professora Ana Gonçalves Magalhães.
Theodor Heuberger, Kunsthändler: Entre predileções artísticas modernistas e a propaganda nazista no Brasil (1924-1942)
Authors: Mari Marcelo 
Published: May 2021

Theodor Heuberger foi Kunsthändler atuante no Rio de Janeiro e em São Paulo. Com formação em Munique, realizou exposições no Brasil com obras importantes do expressionismo alemão; foi, também, o primeiro a expor no país a artista Käthe Kollwitz. Além disso, difundiu, no ambiente cultural brasileiro, padrões renovados de desenho de lojas e de expografia ligados ao gosto estético do Deutscher Werkbund. Em que pese sua atuação em prol do expressionismo, Heuberger fundou uma revista de trocas culturais entre Alemanha e Brasil na qual a arte moderna dividiria espaço, progressivamente durante as décadas de 1930 e 1940, com notícias oficiais da Alemanha. De incentivadora da arte moderna alemã, a revista Intercâmbio terminaria seus dias como veículo de propaganda nazista.
Modernidade e desmaterialização na obra tardia de Gustave Moreau
Authors: Vasconcellos Mariana Garcia 
Published: May 2021

Em sua fase final, a obra de Gustave Moreau passa por um processo de desmaterialização que é comum a outros artistas de sua geração. Por meio da análise da pintura e das anotações pessoais de Moreau, este artigo busca compreender as estratégias artísticas e as implicações teóricas envolvidas nesse movimento de idealização do conceito de “obra de arte”. São discutidos o uso simbolicamente carregado do inacabamento da pintura e a descentralização da “obra”, desdobrada em múltiplos estudos e trabalhos menores. Partindo do caso específico do artista, busca-se também contribuir para uma perspectiva geral sobre questões-chave da pintura moderna.
Teoria da maturidade progressiva do menor aplicada no direito à saúde
Authors: Araújo Rodrigo Vasconcelos Coelho de 
Published: May 2021

O presente artigo analisou os limites do poder familiar nos casos envolvendo recusa de tratamento médico por adolescentes. A partir dos dispositivos constitucionais e infraconstitucionais, pretendeu-se fazer uma releitura da autonomia do adolescente e, em virtude do fenômeno da mundialização dos juízes, reforçar no Direito brasileiro alguns fundamentos oriundos de precedente inglês que deu origem à teoria do menor maduro. Concluiu-se com a análise dos fundamentos e dos requisitos para a recusa de tratamento médico por adolescentes no direito brasileiro.
COVID-19: parâmetros internacionais, federalismo e a atuação internacional dos estados e municípios
Authors: Silva Gabriela Fideles , Guimarães Vinícius César 
Published: May 2021

Tendo como contexto os impactos da pandemia do novo coronavírus e a relevância dada às recomendações da Organização Mundial da Saúde, este artigo buscou abordar – sob a ótica do Direito Internacional Público e das Relações Internacionais - as políticas de saúde sugeridas pelos parâmetros internacionais de enfrentamento da pandemia da COVID-19. A partir de documentos internacionais, artigos acadêmicos e informações veiculadas por meios de comunicação, analisou-se a adoção dessas políticas pelo governo federal e por seus entes subnacionais, levando-se em conta, por fim, as ações paradiplomáticas despertadas e suas consequências para o sistema federalista brasileiro. Com base na revisão da literatura pertinente, buscou-se apresentar os parâmetros internacionais que concernem à saúde; quais são os aspectos do sistema federalista brasileiro no que diz respeito à saúde; e, com base nesse estudo, qual é o efeito do federalismo na luta contra a COVID-19 e como ele pode colaborar para uma atuação cada vez maior de estados e municípios nas relações internacionais. Por fim, examinou-se a definição de paradiplomacia para se compreender o poder que os entes da União possuem no cenário internacional. Concluiu-se que os tratados e organizações internacionais têm um papel fundamental na efetivação do direito à saúde, servindo de base para que o Judiciário permita que estados e municípios tomem medidas mais restritivas no combate à COVID-19. Percebeu-se, ainda, que a falta de liderança do governo federal e a autonomia detida pelos entes federativos permitiram que estes desenvolvessem um protagonismo maior nas relações internacionais no contexto da pandemia.
Colchicine to Prevent Periprocedural Myocardial Injury in Percutaneous Coronary Intervention: The COPE-PCI Pilot Trial
Authors: Cole Justin , Htun Nay , Lew Robert , Freilich Mark , Quinn Stephen , Layland Jamie 
Published: May 2021

Background:
Periprocedural myocardial infarction and injury (PM-injury) are the most common complications of percutaneous coronary intervention (PCI) and are associated with future adverse cardiac events. Inflammation plays a pivotal role in the development of PM-injury. In this randomized pilot trial, we assessed the effect of an anti-inflammatory medication colchicine on periprocedural myocardial injury.

Methods:
Patients undergoing PCI for stable angina or non–ST-segment–elevation myocardial infarction were randomized to oral colchicine (1 mg followed by 0.5 mg 1 hour later) or placebo, 6 to 24 hours preprocedure. Blood samples were taken immediately pre- and 24-hours post-PCI. The primary outcome, periprocedural myocardial infarction, was defined by an increase in post-PCI troponin >5×99th% upper reference limit when the pre-PCI troponin was normal, or >20% increase in post-PCI troponin when the pre-PCI troponin was raised, including supporting evidence of new myocardial ischemia. Major PM-injury was defined as per periprocedural myocardial infarction without supporting evidence of new myocardial ischemia. Minor PM-injury was defined by post-PCI troponin increase >99th% upper reference limit but ≤5×99th% upper reference limit.

Results:

A total of 196 patients met inclusion criteria and were randomized. One hundred twenty-one patients were excluded (no PCI, unstable troponin before PCI, or poor-quality measurements) leaving a study population of 75 patients. Thirty-six patients were randomized to colchicine and 39 to placebo preprocedure. Forty-four presented with non–ST-segment–elevation myocardial infarction and 31 with stable angina. High-sensitive (hs) troponin-I pre-PCI was similar between treatment groups (colchicine: 79 ng/L [4–1336] versus placebo: 35 [5–448],
P
=0.42). Absolute change in hs-troponin-I (calculated as 24-hour post-PCI minus pre-PCI measurements) was significantly lower in the colchicine group: 59 (1–221) versus placebo: 166 (53–530),
P
=0.02. No patients developed periprocedural myocardial infarction in either group. Significantly fewer patients developed major PM-injury: 11 (31%) versus 21 (54%),
P
=0.04 or minor PM-injury: 21 (58%) versus 33 (85%),
P
=0.01, if given colchicine pre-PCI.

Conclusions:
In this randomized pilot trial, colchicine given 6 to 24 hours pre-PCI reduces periprocedural myocardial injury.

Registration:

URL:
https://www.anzctr.org.au
; Unique identifier: ACTRN12615000485538.
Changes in Home Blood Pressure Monitored Among Elderly Patients With Hypertension During the COVID-19 Outbreak: A Longitudinal Study in China Leveraging a Smartphone-Based Application
Authors: Zhang Shuyuan , Zhou Xiaoyang , Chen Youren , Wang Lixin , Zhu Bingpo , Jiang Yinong , Bu Peili , Liu Wei , Li Dianfang , Li Yuming , Tao Yanhua , Ren Jie , Fu Li , Li Yufeng , Shen Xiaomei , Liu Hualing , Sun Gang , Xu Xinjuan , Bai Jingjing , Zhang Weili , Cai Jun ,   On behalf of the STEP Study Group
Published: May 2021

Background:
The coronavirus disease 2019 (COVID-19) pandemic has impacted clinical care worldwide. Evidence of how this health crisis affected common conditions like blood pressure (BP) control is uncertain.

Methods:
We used longitudinal BP data from an ongoing randomized clinical trial to examine variations in home BP monitored via a smartphone-based application (app) in a total of 7394 elderly patients with hypertension aged 60 to 80 years stratified by their location in Wuhan (n=283) compared with other provinces of China (n=7111). Change in morning systolic BP (SBP) was analyzed for 5 30-day phases during the pandemic, including preepidemic (October 21 to November 20, 2019), incubation (November 21 to December 20, 2019), developing (December 21, 2019 to January 20, 2020), outbreak (January 21 to February 20, 2020), and plateau (February 21 to March 21, 2020).

Results:

Compared with non-Wuhan areas of China, average morning SBP (adjusted for age, sex, body mass index) in Wuhan patients was significantly higher during the epidemic growth phases, which returned to normal at the plateau. Between-group differences in ΔSBP were +2.5, +3.0, and +2.1 mm Hg at the incubation, developing, and outbreak phases of COVID-19 (
P
<0.001), respectively. Sensitivity analysis showed a similar trend in trajectory pattern of SBP in both the intensive and standard BP control groups of the trial. Patients in Wuhan also had an increased regimen change in antihypertensive drugs during the outbreak compared with non-Wuhan patients. Expectedly, Wuhan patients were more likely to check their BP via the app, while doctors were less likely to monitor the app for BP control during the pandemic.

Conclusions:
Our data demonstrate that the COVID-19 pandemic was associated with a short-term increase in morning SBP among elderly patients with hypertension in Wuhan but not other parts of China. Further study will be needed to understand if these findings extended to other parts of the world substantially affected by the virus.

Registration:

URL:
https://www.clinicaltrials.gov
. Unique identifier: NCT03015311.
Racial and Ethnic Disparities in Heart and Cerebrovascular Disease Deaths During the COVID-19 Pandemic in the United States
Authors: Wadhera Rishi K. , Figueroa Jose F. , Rodriguez Fatima , Liu Michael , Tian Wei , Kazi Dhruv S. , Song Yang , Yeh Robert W. , Joynt Maddox Karen E. 
Published: May 2021

Background:
Cardiovascular deaths increased during the early phase of the COVID-19 pandemic in the United States. However, it is unclear whether diverse racial/ethnic populations have experienced a disproportionate rise in heart disease and cerebrovascular disease deaths.

Methods:
We used the National Center for Health Statistics to identify heart disease and cerebrovascular disease deaths for non-Hispanic White, non-Hispanic Black, non-Hispanic Asian, and Hispanic individuals from March to August 2020 (pandemic period), as well as for the corresponding months in 2019 (historical control). We determined the age- and sex-standardized deaths per million by race/ethnicity for each year. We then fit a modified Poisson model with robust SEs to compare change in deaths by race/ethnicity for each condition in 2020 versus 2019.

Results:

There were a total of 339 076 heart disease and 76 767 cerebrovascular disease deaths from March through August 2020, compared with 321 218 and 72 190 deaths during the same months in 2019. Heart disease deaths increased during the pandemic in 2020, compared with the corresponding period in 2019, for non-Hispanic White (age–sex standardized deaths per million, 1234.2 versus 1208.7; risk ratio for death [RR], 1.02 [95% CI, 1.02–1.03]), non-Hispanic Black (1783.7 versus 1503.8; RR, 1.19 [95% CI, 1.17–1.20]), non-Hispanic Asian (685.7 versus 577.4; RR, 1.19 [95% CI, 1.15–1.22]), and Hispanic (968.5 versus 820.4; RR, 1.18 [95% CI, 1.16–1.20]) populations. Cerebrovascular disease deaths also increased for non-Hispanic White (268.7 versus 258.2; RR, 1.04 [95% CI, 1.03–1.05]), non-Hispanic Black (430.7 versus 379.7; RR, 1.13 [95% CI, 1.10–1.17]), non-Hispanic Asian (236.5 versus 207.4; RR, 1.15 [95% CI, 1.09–1.21]), and Hispanic (264.4 versus 235.9; RR, 1.12 [95% CI, 1.08–1.16]) populations. For both heart disease and cerebrovascular disease deaths, Black, Asian, and Hispanic populations experienced a larger relative increase in deaths than the non-Hispanic White population (interaction term,
P
<0.001).

Conclusions:
During the COVID-19 pandemic in the United States, Black, Hispanic, and Asian populations experienced a disproportionate rise in deaths caused by heart disease and cerebrovascular disease, suggesting that these groups have been most impacted by the indirect effects of the pandemic. Public health and policy strategies are needed to mitigate the short- and long-term adverse effects of the pandemic on the cardiovascular health of diverse populations.
Non–High-Density Lipoprotein Cholesterol Predicts Adverse Outcomes in Acute Ischemic Stroke
Authors: Wang Guangyao , Jing Jing , Wang Anxin , Zhang Xiaoli , Zhao Xingquan , Li Zixiao , Wang Chunjuan , Li Hao , Liu Liping , Wang Yongjun , Wang Yilong ,   on behalf of the China National Stroke Registry II Investigators
Published: May 2021

Background and Purpose:
Non–high-density lipoprotein cholesterol (non–HDL-C) was significantly related to adverse outcomes in patients with cardiovascular disease. We aim to investigate the associations of non-HDL-C and adverse outcomes in acute ischemic stroke.

Methods:
Among 19 604 patients with acute ischemic stroke admitted to the China National Stroke Registry II, 16 113 with both total cholesterol and HDL-C were analyzed. Patients were classified into 5 groups by quintiles of non-HDL-C. The outcomes included recurrent ischemic stroke, intracranial hemorrhage, and all-cause death within 1 year. The relationship of non-HDL-C with the risk of outcomes was analyzed by Cox regression models.

Results:
Among the 16 113 patients, the median (interquartile range) of non-HDL-C was 3.41 (2.78–4.10) mmol/L. After adjustment for confounding variables, patients in the top quintile of non-HDL-C were associated with higher risk of recurrent ischemic stroke within 1 year (adjusted hazard ratio, 1.46 [95% CI, 1.20–1.77]), compared with those in the third quintile. Patients in the bottom and top quintile of non-HDL-C were associated with higher risk of all-cause death within 1 year (adjusted hazard ratio, 1.22 [95% CI, 1.01–1.47] and adjusted hazard ratio, 1.40 [95% CI, 1.15–1.70], respectively), compared with those in the third quintile. However, non-HDL-C levels were not significantly predictive in intracranial hemorrhage.

Conclusions:
Non-HDL-C may be a qualified predictor for recurrent ischemic stroke and all-cause death within 1 year in patients with acute ischemic stroke.
Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign
Authors: Ovesen Christian , Jakobsen Janus Christian , Gluud Christian , Steiner Thorsten , Law Zhe , Flaherty Katie , Dineen Rob A. , Christensen Louisa M. , Overgaard Karsten , Rasmussen Rune S. , Bath Philip M. , Sprigg Nikola , Christensen Hanne ,   the TICH-2 Investigators
Published: May 2021

Background and Purpose:
The computed tomography angiography or contrast-enhanced computed tomography based spot sign has been proposed as a biomarker for identifying on-going hematoma expansion in patients with acute intracerebral hemorrhage. We investigated, if spot-sign positive participants benefit more from tranexamic acid versus placebo as compared to spot-sign negative participants.

Methods:
TICH-2 trial (Tranexamic Acid for Hyperacute Primary Intracerebral Haemorrhage) was a randomized, placebo-controlled clinical trial recruiting acutely hospitalized participants with intracerebral hemorrhage within 8 hours after symptom onset. Local investigators randomized participants to 2 grams of intravenous tranexamic acid or matching placebo (1:1). All participants underwent computed tomography scan on admission and on day 2 (24±12 hours) after randomization. In this sub group analysis, we included all participants from the main trial population with imaging allowing adjudication of spot sign status.

Results:

Of the 2325 TICH-2 participants, 254 (10.9%) had imaging allowing for spot-sign adjudication. Of these participants, 64 (25.2%) were spot-sign positive. Median (interquartile range) time from symptom onset to administration of the intervention was 225.0 (169.0 to 310.0) minutes. The adjusted percent difference in absolute day-2 hematoma volume between participants allocated to tranexamic versus placebo was 3.7% (95% CI, −12.8% to 23.4%) for spot-sign positive and 1.7% (95% CI, −8.4% to 12.8%) for spot-sign negative participants (
P
heterogenity
=0.85). No difference was observed in significant hematoma progression (dichotomous composite outcome) between participants allocated to tranexamic versus placebo among spot-sign positive (odds ratio, 0.85 [95% CI, 0.29 to 2.46]) and negative (odds ratio, 0.77 [95% CI, 0.41 to 1.45]) participants (
P
heterogenity
=0.88).

Conclusions:
Data from the TICH-2 trial do not support that admission spot sign status modifies the treatment effect of tranexamic acid versus placebo in patients with acute intracerebral hemorrhage. The results might have been affected by low statistical power as well as treatment delay.

Registration:

URL:
http://www.controlled-trials.com
; Unique identifier: ISRCTN93732214.
Predicting 90-Day Outcome After Thrombectomy: Baseline-Adjusted 24-Hour NIHSS Is More Powerful Than NIHSS Score Change
Authors: Mistry Eva A. , Yeatts Sharon , de Havenon Adam , Mehta Tapan , Arora Niraj , De Los Rios La Rosa Felipe , Starosciak Amy K. , Siegler James E. , Mistry Akshitkumar M. , Yaghi Shadi , Khatri Pooja 
Published: May 2021

Background and Purpose:
The National Institutes of Health Stroke Scale (NIHSS) measured at an early time point is an appealing surrogate marker for long-term functional outcome of stroke patients treated with endovascular therapy. However, definitions and analytical methods for an early NIHSS-based outcome measure that optimize power and precision in clinical studies are not well-established.

Methods:
In this post-hoc analysis of our prospective observational study that enrolled endovascular therapy-treated patients at 12 comprehensive stroke centers across the US, we compared the ability of 24-hour NIHSS, ΔNIHSS (baseline minus 24-hour NIHSS), and percentage change (NIHSS×100/baseline NIHSS), analyzed as continuous and dichotomous measures, to predict 90-day modified Rankin Scale (mRS) using logistic regression (adjusted for age, baseline NIHSS, glucose, hypertension, Alberta Stroke Program Early CT Score, time to recanalization, recanalization status, and intravenous thrombolysis) and Spearman ρ.

Results:

Of 485 patients in the BEST (Blood Pressure After Endovascular Stroke Therapy) cohort, 446 (92%) with 90-day follow-up data were included. An absolute 24-hour NIHSS, adjusted for baseline in multivariable modeling, had the highest predictive power of all definitions evaluated (aR
2
0.368 and adjusted odds ratio 0.79 [0.75–0.84],
P
<0.001 for mRS score 0–2; aR
2
0.444 and adjusted odds ratio 0.84 [0.8–0.86] for ordinal mRS). For predicting mRS score of 0–2 with a cut point, the second most efficient approach, the optimal threshold for 24-hour NIHSS score was ≤7 (sensitivity 80.1%, specificity 80.4%; adjusted odds ratio 12.5 [7.14–20],
P
<0.001), followed by percent change in NIHSS (sensitivity 79%, specificity 58.5%; adjusted odds ratio 4.55 [2.85–7.69],
P
<0.001).

Conclusions:
Twenty-four–hour NIHSS, adjusted for baseline, was the strongest predictor of both dichotomous and ordinal 90-day mRS outcomes for endovascular therapy-treated patients. A dichotomous 24-hour NIHSS score of ≤7 was the second-best predictor. Although ΔNIHSS, continuous and dichotomized at ≥4, predicted 90-day outcomes, absolute 24-hour NIHSS definitions performed better.
Nineteen new species of Alycaeidae from Myanmar and Thailand (Gastropoda: Caenogastropoda: Cyclophoroidea)
Authors: PÁLL-GERGELY BARNA , HUNYADI ANDRÁS , GREGO JOZEF , REISCHÜTZ ALEXANDER , AUFFENBERG KURT 
Published: May 2021

Nineteen new species of the alycaeid genera Chamalycaeus, Dicharax, and Metalycaeus are described from Thailand and Myanmar: Chamalycaeus buaboke Páll-Gergely & A. Reischütz, n. sp., C. erawan Páll-Gergely & Hunyadi, n. sp., C. hirpex Páll-Gergely & A. Reischütz, n. sp., C. irmatallus Páll-Gergely, n. sp., C. krabiensis Páll-Gergely & A. Reischütz, n. sp., C. serratus Páll-Gergely & Auffenberg, n. sp., C. spiratus Páll-Gergely, n. sp., Dicharax (?) admirandus Páll-Gergely & Auffenberg, n. sp., D. cyclostoma Páll-Gergely, n. sp., D. ebrius Páll-Gergely & Auffenberg, n. sp., D. (?) gnomus Páll-Gergely, n. sp., D. mirounga Páll-Gergely, n. sp., D. ovatus Páll-Gergely & Auffenberg, n. sp., D. subroseus Páll-Gergely, n. sp., D. verrucosus Páll-Gergely & Hunyadi, n. sp., Metalycaeus anas Páll-Gergely & A. Reischütz, n. sp., M. aries Páll-Gergely & Auffenberg, n. sp., M. bicarinatus Páll-Gergely & Hunyadi, n. sp., M. pygmachos Páll-Gergely & Hunyadi, n. sp. Alycaeus kengtungensis Godwin-Austen, 1914 is moved to the synonymy of Metalycaeus heudei (Bavay & Dautzenberg, 1900). We also report exact localities of Dicharax ataranensis (Godwin-Austen, 1914), Dicharax notus (Godwin-Austen, 1914), and Dicharax omissus (Godwin-Austen, 1914). The new records extend the known distribution of Chamalycaeus and Metalycaeus in Thailand.
Climatological sensitivities of shallow-cumulus bulk entrainment in continental and oceanic locations
Authors: Kirshbaum Daniel J. , Lamer Katia 
Published: May 2021

AbstractCumulus entrainment is a complex process that has long challenged conceptual understanding and atmospheric prediction. To investigate this process observationally, two retrievals are used to generate multi-year climatologies of shallow-cumulus bulk entrainment (ϵ) at two Atmospheric Radiation Measurement cloud observatories, one in the US southern Great Plains (SGP) and the other in the Azores archipelago in the eastern North Atlantic (ENA). The statistical distributions of ϵ thus obtained, as well as certain environmental and cloud-related sensitivities of ϵ, are consistent with previous findings from large-eddy simulations. The retrieved ϵ robustly increases with cloudlayer relative humidity and decreases in wider clouds and cloud ensembles with larger cloud-base mass fluxes. While ϵ also correlates negatively with measures of cloud-layer vigor (e.g., maximum in-cloud vertical velocity and cloud depth), the extent to which these metrics actually regulate ϵ (or vice-versa) is unclear. Novel sensitivities of ϵ include a robust decrease of ϵ with increasing subcloud wind speed in oceanic flows, as well as a decrease of ϵ with increasing cloud-base mass flux in individual cumuli. A strong land–ocean contrast in ϵ is also found, with median values of 0.5-0.6 km−1 at the continental SGP site and and 1.0-1.1 km−1 at the oceanic ENA site. This trend is associated with drier and deeper cloud layers, along with larger cloud-base mass fluxes, at SGP, all of which favor reduced ϵ. The flow-dependence of retrieved ϵ implies that its various sensitivities should be accounted for in cumulus parameterization schemes.