bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estresse, a realidade e o desafio do professor contemporâneo
Authors: Lopes Gabriel César Dias 
Published: October 2021

A incidência do estresse segue os passos de um processo produtivo que numa análise geral da questão é a motivadora do quadro de saúde precária do trabalhador no país Para a compreensão da relação saúde/trabalho e do trabalho docente em um contexto neoliberal e dos seus efeitos, esse artigo busca compreender a semântica da terminologia estresse, a trajetória deste no contexto das doenças ocupacionais no capitalismo neoliberal e enfim a situação do professor que exigido em excelência se depara com situações onde o nível de estresse ocupacional e de outras doenças geradas a partir dele. A situação atual do trabalho e da saúde do trabalhador em educação nos moldes do capitalismo mundial e mais especificamente no Brasil, destaca a necessidade de uma pesquisa acerca da trajetória da exploração do trabalho que, independente dos processos produtivos que marcaram a história econômica do país. Os teóricos aqui reportados são Edgar Morin, Pedro Demo, Fritjof Capra, GyorgyLuckács,Carlos Minayo-Gomez,Michel Foucault entre outros
تأثير معدلات تسميد نيتروجيني على بعض الخصائص الفسيولوجية لمحصول الشعير .Hordeum vulgare L بمنطقتي مراوة والوسيطة بالجبل الأخضر في ليبيا.
Authors: حسين الطيب فرج , بوكليلة أحمد عبد الله 
Published: October 2021

تهدف هذه الدراسة لمعرفة سلوك محصول الشعير باختلاف البيئة لمستويات النيتروجين المضاف في صورة يوريا 46%. أقيمت تجربة حقلية في منطقتي مراوة جنوب الجبل الأخضر والوسيطة الواقعتين على خطي عرض̊21 2̀4̀، ̊21 3̀9شمالا و32 2̀0̊، ̊32 4̀7 شرقاً وترتفعان 508 و185 متراً فوق مستوى سطح البحر للمنطقتين بالترتيب خلال الموسم الزراعي 2014 /2015 لمعرفة تأثير معدلات النيتروجين (0, 50, 100 ,150 كجم /هـ) على خصائص نمو الشعير صنف ريحان المزروع بالمعدل 70 كجم/هـ بالتسطير على مسافة 15سم. صممت تجربة القطاعات كاملة العشوائية في 4 مكررات في وحدات تجريبية مساحتها 5×5 (25م²)، أظهرت النتائج تسجيل فروق عالية معنوية في معدل نمو المحصول(CGR)، معدل النمو النسبي للمحصول(RGR)، تصافي البناء الضوئي(NAR)، دليل مساحة الأوراق (LAI) بإضافة 150 كجم/ه. زادت استدامة المحصول(BMD) بفروق معنوية عالية بإضافة المعدل 100 كجم/ه مقارنة بعدم التسميد في كلا موقعي الدراسة. زاد محتوى الأوراق من الكلوروفيل أ chla)) في منطقتي الدراسة للمعدل 150 كجم/ه وعدم تأثر محتوى الأوراق من الكلوروفيل ب (chlb) والكلي ((Tchl في مراوة وبفروق معنوية في الوسيطة عند إضافة 150 كجم/ه لكلوروفيل ب و100 كجم/ه للكلوروفيل الكلي.
Non-Tariff Measures (NTM) and Their Significance in Agricultural Trade of India and European Union
Authors: Niranjan M. B. , Shivakumar K. M. , Prahadeeswaran M. , Rohini A. 
Published: October 2021

Aims: The research study aims to study the decadal growth in agricultural trade of top five agricultural commodities between India and the European Union and also the quantification of Non-Tariff Measures (NTM) of select agricultural commodities to give trade policy suggestions to the concerned commodity sectors
Study Design and Methodology: A decadal growth in top five agricultural commodities were studied for 28 European Union Countries (EU-28) and India using Compounded Annual Growth Rate and NTM of three subsections of WTO were quantified using inventory-based approaches; coverage ratio and frequency index.
Results and Conclusion: In terms of quantity exported, positive annual growth rate of 0.24, 0.48 and 0.76 per cent in marine products, coffee and castor oil is noticed. A negative growth of 0.67 and 2.6 per cent in spices and tobacco unmanufactured is witnessed during the study period. Export value recorded the positive annual growth rate of 2.96, per cent in marine products and spices and a negative growth of 1.7,0.16 and 2.8 per cent in coffee, castor oil and tobacco unmanufactured respectively. Export value per unit showed annual positive growth of 2.7,2.2 and 0.94 per cent in marine products, coffee and spices and negative growth of 0.91 and 0.22 per cent in castor oil and tobacco unmanufactured respectively. Both Sanitary and Phyto Sanitary (SPS) and Technical Barriers to Trade (TBT) Measures had a greater impact in the agricultural export form India to EU-28 during 2010-11 to 2019-20.
Advanced Multifunctional Aqueous Rechargeable Batteries Design: From Materials and Devices to Systems
Authors: Li Lei , Zhang Qichong , He Bing , Pan Rui , Wang Zhixun , Chen Mengxiao , Wang Zhe , Yin Kuibo , Yao Yagang , Wei Lei , Sun Litao 
Published: October 2021

AbstractMultifunctional aqueous rechargeable batteries (MARBs) are regarded as safe, cost‐effective, and scalable electrochemical energy storage devices, which offer additional functionalities that conventional batteries cannot achieve, which ideally leads to unprecedented applications. Although MARBs are among the most exciting and rapidly growing topics in scientific research and industrial development nowadays, a systematic summary of the evolution and advances in the field of MARBs is still not available. Therefore, the review presented comprehensively and systematically summarizes the design principles and the recent advances of MARBs by categories of smart ARBs and integrated systems, together with an analysis of their device design and configuration, electrochemical performance, and diverse smart functions. The two most promising strategies to construct novel MARBs may be A) the introduction of functional materials into ARB components, and B) integration of ARBs with other functional devices. The ongoing challenges and future perspectives in this research and development field are outlined to foster the future development of MARBs. Finally, the most important upcoming research directions in this rapidly developing field are highlighted that may be most promising to lead to the commercialization of MARBs and to a further broadening of their range of applications.
Polyprodrug Nanomedicines: An Emerging Paradigm for Cancer Therapy
Authors: Yang Kuikun , Yang Zhiqing , Yu Guocan , Nie Zhihong , Wang Ruibing , Chen Xiaoyuan 
Published: October 2021

AbstractNanomedicines have the potential to provide advanced therapeutic strategies in combating tumors. Polymer‐prodrug‐based nanomedicines are particularly attractive in cancer therapies owing to the maximum drug loading, prolonged blood circulation, and reduced premature leakage and side effects in comparison with conventional nanomaterials. However, the difficulty in precisely tuning the composition and drug loading of polymer–drug conjugates leads to batch‐to‐batch variations of the prodrugs, thus significantly restricting their clinical translation. Polyprodrug nanomedicines inherit the numerous intrinsic advantages of polymer–drug conjugates and exhibit well‐controlled composition and drug loading via direct polymerization of therapeutic monomers, representing a promising nanomedicine for clinical tumor therapies. In this review, recent advances in the development of polyprodrug nanomedicines are summarized for tumor elimination. Various types of polyprodrug nanomedicines and the corresponding properties are first summarized. The unique advantages of polyprodrug nanomedicines and their key roles in various tumor therapies are further highlighted. Finally, current challenges and the perspectives on future research of polyprodrug nanomedicines are discussed.
An Enzyme‐Activatable Aggregation‐Induced‐Emission Probe: Intraoperative Pathological Fluorescent Diagnosis of Pancreatic Cancer via Specific Cathepsin E
Authors: Zhu Zhirong , Wang Qi , Chen Xiaoyan , Wang Quan , Yan Chengxu , Zhao Xiaolei , Zhao Weijun , Zhu Wei‐Hong 
Published: October 2021

AbstractPancreatic cancer (PC) is one of the most devastating malignant tumors. However, fluorescence probes for early clinical diagnosis of PC often encounter difficulties in accuracy and penetrability. In this work, an enzyme‐activated aggregation‐induced‐emission (AIE) probe, QM–HSP–CPP, for high‐contrast fluorescence diagnosis of PC is developed by monitoring specific overexpressed enzyme Cathepsin E (CTSE). The probe is composed of an AIE fluorophore QM–COOH (QM = quinoline–malononitrile), CTSE‐triggered hydrophobic peptide (HSP), and hydrophilic biocompatible cell penetrating peptide (CPP). The CPP unit can well‐modulate the molecular dispersion properties, giving initial fluorescence‐off state in the aqueous biosystem, thus endowing high signal‐to‐noise ratio, and finally overcoming the poor targeting selectivity of traditional AIE probes. CPP can ensure cell/tissue penetrating ability, thus allowing on‐site monitoring of endogenous CTSE in PC cells, tissues, and living animal models. When the QM–HSP–CPP probe is specifically cleaved by CTSE, it can generate AIE signals in situ with high‐specificity and long‐term tracking ability, and successfully achieve intraoperative diagnosis of human PC sections, tracking PC in heterotopic nude mice models. The CTSE‐enzyme‐triggered AIEgens’ liberation strategy improves accuracy and addresses the penetration problem simultaneously, which can expand the database of multitudinous biocompatible AIE‐active probes, especially for establishing intraoperative pathological fluorescent diagnosis.
Cephalopod‐Inspired Design of Photomechanically Modulated Display Systems for On‐Demand Fluorescent Patterning
Authors: Shi Huihui , Wu Shuangshuang , Si Muqing , Wei Shuxin , Lin Guoqing , Liu Hao , Xie Weiping , Lu Wei , Chen Tao 
Published: October 2021

AbstractCephalopods can display variable body color/patterns upon environmental stimulation via bioelectricity‐controlled muscle contraction/expansion of skin chromatophores. However, it remains challenging to produce artificial display analogs that exhibit reversible and rapid switching between multiple expected luminescent patterns, although such systems are very appealing for many practical uses (e.g., data encryption). Inspired by the bioelectromechanical display tactic of cephalopods, in this work, a conceptually new photomechanically modulated fluorescent system that enables on‐demand display of fluorescent patterns via a cascading stimulation−mechanical movement−optical output conduction mechanism is presented. Specifically, this biomimetic system comprises a customizable hollow display panel and a bottom‐tethered photothermally responsive fluorescent actuator. Under NIR light, the photomechanically bending movements of the fluorescent actuator will immediately cover the hollow window of the display panel and synchronously manifest as the display of fluorescent patterns. Owing to its desirable time‐ and light‐power‐dependent actuating behaviors, diverse fluorescent patterns/information can be dynamically and reversibly displayed by facilely controlling this single remote NIR signal. This bioinspired strategy is universal and promising for fabricating on‐demand fluorescent display platforms that combine a wide choice of fluorophores, remote control with high spatial/temporal precision, and especially single‐input multiple‐output features.
Lead‐Free All‐Inorganic Indium Chloride Perovskite Variant Nanocrystals for Efficient Luminescence
Authors: Han Peigeng , Zhou Wei , Zheng Daoyuan , Zhang Xirui , Li Cheng , Kong Qingkun , Yang Songqiu , Lu Ruifeng , Han Keli 
Published: October 2021

AbstractLead‐free halide perovskites and their variants have attracted great attention due to their non‐toxicity and good photophysical properties. Here, a series of undoped and antimony‐doped all‐inorganic, 0D, indium‐based perovskite variant nanocrystals (NCs): (RbxCs1−x)3InCl6 and (RbxCs1−x)3InCl6:Sb (0 ≤ x ≤ 1) NCs, is reported. Among them, Sb‐doped NCs exhibit green emission. Mixing Rb‐Cs NCs show the higher photoluminescence (PL) quantum efficiency (PLQE) and better stability than unalloyed NCs (x = 0 or 1). The effect of crystal size on PL property of (Rb0.75Cs0.25)3InCl6:Sb is analyzed in detail. More interestingly, In‐based perovskite variant NCs containing coordinated water are successfully synthesized by a two‐step method (variable temperature hot injection and saturated steam post treatment). The best PLQE of Sb‐doped Cs2InCl5(H2O) NCs reaches 95.5%, which is a new PLQE record for yellow emissive lead‐free perovskite and variant NCs. In addition, the emission mechanism is further clarified by temperature‐dependent PL and femtosecond transient absorption techniques.
Ultrahigh Stability of Wearable Photodetector Using Zirconium Metal‐Organic Framework Enabling In Situ and Continuous Monitoring of Ultraviolet Radiation Risk
Authors: Tran Manh Hoang , Hur Jaehyun 
Published: October 2021

AbstractZirconium‐benzenedicarboxylate (ZrBDC) is a remarkably stable metal‐organic framework with a broadband UV absorption that would offer numerous applications related to UV detection. However, the integration of a continuous and densely packed ZrBDC film with the controllable thickness into optoelectrical devices suffers from time‐consuming and complicated fabrication of ZrBDC thin film. In this study, a facile liquid‐phase epitaxy method is introduced by adopting sequential and continuous layer‐by‐layer spin‐coating technique to fabricate the high‐quality ZrBDC thin film. The structural, optical, and electrical properties of the as‐prepared ZrBDC thin film are characterized by X‐ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, ultraviolet‐visible spectroscopy, photoluminescence spectroscopy, space charge limited current, and Mott‐Schottky measurement. When ZrBDC is used as an efficient photo‐absorber layer for a visible‐blind UV photodetector, the device exhibits a specific detectivity of 7.85 × 1010 Jones and rise/fall time of 80/150 ms at zero bias. Furthermore, the device reveals outstanding stability with nearly constant photoresponse during 19 h‐exposure to UV illumination and after storing for 2 months, along with excellent tolerance under high operating temperature and bending strain. For practical applications, the facile estimation of UV level under sunlight is demonstrated using a wearable UV detector based on ZrBDC.
Photocatalytic Air Purification Using Functional Polymeric Carbon Nitrides
Authors: Zhou Min , Ou Honghui , Li Shanrong , Qin Xing , Fang Yuanxing , Lee Shun‐cheng , Wang Xinchen , Ho Wingkei 
Published: October 2021

AbstractThe techniques for the production of the environment have received attention because of the increasing air pollution, which results in a negative impact on the living environment of mankind. Over the decades, burgeoning interest in polymeric carbon nitride (PCN) based photocatalysts for heterogeneous catalysis of air pollutants has been witnessed, which is improved by harvesting visible light, layered/defective structures, functional groups, suitable/adjustable band positions, and existing Lewis basic sites. PCN‐based photocatalytic air purification can reduce the negative impacts of the emission of air pollutants and convert the undesirable and harmful materials into value‐added or nontoxic, or low‐toxic chemicals. However, based on previous reports, the systematic summary and analysis of PCN‐based photocatalysts in the catalytic elimination of air pollutants have not been reported. The research progress of functional PCN‐based composite materials as photocatalysts for the removal of air pollutants is reviewed here. The working mechanisms of each enhancement modification are elucidated and discussed on structures (nanostructure, molecular structue, and composite) regarding their effects on light‐absorption/utilization, reactant adsorption, intermediate/product desorption, charge kinetics, and reactive oxygen species production. Perspectives related to further challenges and directions as well as design strategies of PCN‐based photocatalysts in the heterogeneous catalysis of air pollutants are also provided.
Control over Electrochemical CO2 Reduction Selectivity by Coordination Engineering of Tin Single‐Atom Catalysts
Authors: Guo Jiangyi , Zhang Wenlin , Zhang Lu‐Hua , Chen Datong , Zhan Jiayu , Wang Xueli , Shiju N. Raveendran , Yu Fengshou 
Published: October 2021

AbstractCarbon‐based single‐atom catalysts (SACs) with well‐defined and homogeneously dispersed metal−N4 moieties provide a great opportunity for CO2 reduction. However, controlling the binding strength of various reactive intermediates on catalyst surface is necessary to enhance the selectivity to a desired product, and it is still a challenge. In this work, the authors prepared Sn SACs consisting of atomically dispersed SnN3O1 active sites supported on N‐rich carbon matrix (Sn‐NOC) for efficient electrochemical CO2 reduction. Contrary to the classic Sn‐N4 configuration which gives HCOOH and H2 as the predominant products, Sn‐NOC with asymmetric atomic interface of SnN3O1 gives CO as the exclusive product. Experimental results and density functional theory calculations show that the atomic arrangement of SnN3O1 reduces the activation energy for *COO and *COOH formation, while increasing energy barrier for HCOO* formation significantly, thereby facilitating CO2‐to‐CO conversion and suppressing HCOOH production. This work provides a new way for enhancing the selectivity to a specific product by controlling individually the binding strength of each reactive intermediate on catalyst surface.
The Optimal Lattice Quantizer in Nine Dimensions
Authors: Allen Bruce , Agrell Erik 
Published: October 2021

AbstractThe optimal lattice quantizer is the lattice that minimizes the (dimensionless) second momentG. In dimensions 1 to 3, it has been proven that the optimal lattice quantizer is one of the classical lattices, and there is good numerical evidence for this in dimensions 4 to 8. In contrast, in 9 dimensions, more than two decades ago, the same numerical studies found the smallest known value ofGfor a non‐classical lattice. The structure and properties of this conjectured optimal lattice quantizer depend upon a real parameter , whose value was only known approximately. Here, a full description of this one‐parameter family of lattices and their Voronoi cells is given, and their (scalar and tensor) second moments are calculated analytically as a function ofa. The value ofawhich minimizesGis an algebraic number, defined by the root of a 9th order polynomial, with . For this value ofa, the covariance matrix (second moment tensor) is proportional to the identity, consistent with a theorem of Zamir and Feder for optimal quantizers. The structure of the Voronoi cell depends upona, and undergoes phase transitions at , 1, and 2, where its geometry changes abruptly. At each transition, the analytic formula for the second moment changes in a very simple way. The methods can be used for arbitrary one‐parameter families of laminated lattices, and may thus provide a useful tool to identify optimal quantizers in other dimensions as well.
Virus‐Mimicking Cell Membrane‐Coated Nanoparticles for Cytosolic Delivery of mRNA
Authors: Park Joon Ho , Mohapatra Animesh , Zhou Jiarong , Holay Maya , Krishnan Nishta , Gao Weiwei , Fang Ronnie H. , Zhang Liangfang 
Published: October 2021

AbstractEffective endosomal escape after cellular uptake represents a major challenge in the field of nanodelivery, as the majority of drug payloads must localize to subcellular compartments other than the endosomes in order to exert activity. In nature, viruses can readily deliver their genetic material to the cytosol of host cells by triggering membrane fusion after endocytosis. For the influenza A virus, the hemagglutinin (HA) protein found on its surface fuses the viral envelope with the surrounding membrane at endosomal pH values. Biomimetic nanoparticles capable of endosomal escape were fabricated using a membrane coating derived from cells engineered to express HA on their surface. When evaluated in vitro, these virus‐mimicking nanoparticles were able to deliver an mRNA payload to the cytosolic compartment of target cells, resulting in the successful expression of the encoded protein. When the mRNA‐loaded nanoparticles were administered in vivo, protein expression levels were significantly increased in both local and systemic delivery scenarios. We therefore conclude that utilizing genetic engineering approaches to express viral fusion proteins on the surface of cell membrane‐coated nanoparticles is a viable strategy for modulating the intracellular localization of encapsulated cargoes.
Photochemical Organocatalytic Regio‐ and Enantioselective Conjugate Addition of Allyl Groups to Enals
Authors: Berger Martin , Carboni Davide , Melchiorre Paolo 
Published: October 2021

AbstractWe report the first catalytic enantioselective conjugate addition of allyl groups to α,β‐unsaturated aldehydes. The chemistry exploits the visible‐light‐excitation of chiral iminium ions to activate allyl silanes towards the formation of allylic radicals, which are then intercepted stereoselectively. The underlying radical mechanism of this process overcomes the poor regio‐ and chemoselectivity that traditionally affects the conjugate allylation of enals proceeding via polar pathways. We also demonstrate how this organocatalytic strategy could selectively install a valuable prenyl fragment at the β‐carbon of enals.
Downregulation of tripartite motif protein 11 attenuates cardiomyocyte apoptosis after ischemia/reperfusion injury via DUSP1‐JNK1/2
Authors: He Fang , Wu Zheqian , Wang Yong , Yin Lili , Lu Shijie , Dai Lihua 
Published: October 2021

AbstractCurrently, the prevention of ischemic diseases such as myocardial infarction associated with ischemia/reperfusion (I/R) injury remains to be a challenge. Thus, this study was designed to explore the effects of tripartite motif protein 11 (TRIM11) on cardiomyocytes I/R injury and its underlying mechanism. Cardiomyocytes AC16 were used to establish an I/R injury cell model. After TRIM11 downregulation in I/R cells, cell proliferation (0, 12, 24, and 48 h) and apoptosis at 48 h as well as the related molecular changes in oxidative stress‐related pathways was detected. Further, after the treatment of TRIM11 overexpression, SP600125, or DUSP1 overexpression, cell proliferation, apoptosis, and related genes were detected again. As per our findings, it was determined that TRIM11 was highly expressed in the cardiomyocytes AC16 after I/R injury. Downregulation of TRIM11 was determined to have significantly reduced I/R‐induced proliferation suppression and apoptosis. Besides, I/R‐activated c‐Jun N‐terminal kinase (JNK) signaling and cleaved caspase 3 and Bax expression were significantly inhibited by TRIM11 downregulation. In addition, the overexpression of TRIM11 significantly promoted apoptosis in AC16 cells, and JNK1/2 inhibition and DUSP1 overexpression potently counteracted the induction of TRIM11 overexpression in AC16 cells. These suggested that the downregulation of TRIM11 attenuates apoptosis in AC16 cells after I/R injury probably through the DUSP1‐JNK1/2 pathways.
Prenatal diagnosis of Pfeiffer syndrome type 2 with increased nuchal translucency
Authors: Hu Zhi‐yang , Lin Sheng‐mou , Zhu Meng‐jie , Cheung Cindy Ka‐Yee , Liu Tao , Zhu Jin 
Published: October 2021

AbstractPfeiffer syndrome (PS) is a rare autosomal dominant genetic disorder characterized by craniosynostosis, broad thumbs / toes. Here, we report a case of PS type 2 with increased nuchal translucency in early trimester.