bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Study, Design and Analysis of a G+12 Structure in Earthquake Zone in India
Authors: Jadhav Kalyani 
Published: July 2021

Seismic isolation is a technology that decouples a building structure from the damaging earthquake motion. It is a simple structural design approach to mitigate or reduce potential earthquake damage. In base-isolated structures, the seismic protection is obtained by shifting the natural period of the structure away from the range of the frequencies for which the maximum amplification effects of the ground motion are expected; thus, the seismic input energy is significantly reduced. At the same time, the reduction of the high deformations attained at the base of the structure is possible, thanks to the energy dissipation caused by the damping and the hysteretic properties of these devices, further improving the reduction of responses of the structures. Base isolation is also an attractive retrofitting strategy to improve the seismic performance of existing bridges and monumental historic building. 	The method of base isolation was developed in an attempt to mitigate the effects of earthquakes on buildings during earthquakes and has been practically proven to be the one of the very effective methods in the past several decades. 	Base isolation consists of the installation of support mechanism which decouples the structure from earthquake induced ground motions. 	Base isolation allows to filter the input forcing functions and to avoid acceleration seismic forces on the structure. 	If the structure is separated from the ground during an earthquake, the ground is moving but the structure experienced little movement. To minimize the transmission of potentially damaging earthquake ground motions into a structure is achieved by the introduction of flexibility at the base of the structure in the horizontal direction while at the same time introducing damping elements to restrict the amplitude or extent of the motion caused by the earthquake somewhat akin to shock absorbers. In recent years this relatively new technology has emerged as a practical and economic alternative to conventional seismic strengthening. This concept has received increasing academic and professional attention and is being applied to a wide range of civil engineering structures. To date there are several hundred buildings in Japan, New Zealand, United States, India which use seismic isolation principles and technology for their seismic design.
THE INFLUENCE FACTORS OF ELECTRONIC WORD OF MOUTH BEHAVIOUR IN FACULTY OF NURSING GARUT CLASS PADJADJARAN UNIVERSITY
Authors: Kamaruddin Novita , Simanjuntak Megawati , Noor Yuliati Lilik 
Published: July 2021

Higher education in increasing competition needs to provide excellent quality services for students to college. Students satisfaction will be encouraged to disseminate their campus information through electronic word of mouth (eWOM). EWOM is a form of consumer willingness to voluntarily provide recommendations for others to buy or use products from companies through the internet. This research was conducted to analyze the quality of service, promotion, brand image and motivation towards eWOM. The research was quantitative research using a descriptive approach. The data were analyzed using SEM Lisrel (Structural Equation Modeling). This study was conducted of student from Faculty of Nursing Garut class who actively carry out lecture with total sample of 309. The findings of this research showed that there was a significant relationship between service quality on brand image, there is a meaningful relationship between the promotion of brand image, there is no significant relationship between service quality on eWOM, brand image has a significant to eWOM and motivation has a significant relationship to eWOM.
Mutation status and immunohistochemical correlation of EGFR mutations in gastrointestinal stromal tumors
Authors: Ozkayalar H , Ergoren MC , Tuncel G , Kurt S , Cevik E , Ozemri Sag S , Yilmaz Ozguven B , Kabukcuoglu F , Mocan G , Temel ŞG 
Published: July 2021

Abstract
Being one of the leading causes of cancer deaths worldwide and their resistance to conventional treatment methods, made gastrointestinal stromal tumors (GISTs) one of the hot topics in medical research areas in the past decade. To investigate molecular alterations underlying the tumor is of great importance to be able to develop new, targeted treatment options. In this study, GIST samples obtained from 40 Turkish patients were analyzed for actionable epidermal growth factor receptor (EGFR) mutations that are related to treatment regimes in non small cell lung cancer (NSCLC) to understand whether EGFR expression is altered in GISTs. Established alterations in EGFR can make the use of tyrosine kinase inhibitors possible, which are currently used in cancer therapy, especially in NSCLC. Our results indicated that EGFR mutations are rare in GISTs. Further research is needed to sequence whole coding regions of the gene to investigate new actionable mutations in EGFR in an increased sample size.
Familial atypical hemolytic uremic syndrome with positive p.S1191L (c.3572C>T) mutation on the CFH gene: A single-center experience
Authors: Ersoy Dursun F , Yesil G , Sasak G , Dursin H 
Published: July 2021

Abstract
The atypical hemolytic uremic syndrome (aHUS) is characterized by thrombocytopenia, microangiopathic hemolytic anemia and acute kidney injury (AKI), which can exhibit a poor prognosis. Complement factor H (CFH) gene mutations play a key role in this disease, which may be sporadic or familial. We studied 13 people from the same family, investigated for gene mutations of the familial aHUS after a family member presented to our emergency clinic with the aHUS and reported a family history of chronic renal failure. The p.S1191L mutation on the CFH gene was heterozygous in six people from the patient’s family with the aHUS. One of these family members is our patient with acute kidney injury, and the other two are followed at the Nephrology Clinic, Medeniyat University, Goztepe Training and Research Hospital, Istanbul, Turkey, due to chronic renal failure. The other three family members showed no evidence of renal failure. The index case had a history of six sibling deaths; three died of chronic renal failure. Plasmapheresis and fresh frozen plasma treatment were administered to our patient. When the patient showed no response to this treatment, eculizumab (ECZ) therapy was started. The study demonstrated that thorough family history should be taken in patients with the aHUS. These patients may have the familial type of the disease, and they should be screened genetically. Eculizumab should be the first choice in the treatment with plasmapheresis. It should be kept in mind that the use of ECZ as prophylaxis in posttransplant therapy is extremely important for preventing rejection.
PCSK9 gene participates in the development of primary dyslipidemias
Authors: Matías-Pérez D , Pérez-Santiago AD , Sánchez Medina MA , Alpuche Osorno JJ , García-Montalvo IA 
Published: July 2021

Abstract
Dyslipidemias are a group of diseases, which are characterized by abnormal blood concentrations of cholesterol, triglycerides and/or low-density lipoprotein-cholesterol (LDL-c). Dyslipidemia is a determinant condition for the progress of an atherosclerotic plaque formation. The resulting atherogenicity is due to at least two mechanisms: first, to the accumulation in the plasma of lipid particles that have the capacity to alter the function of the endothelium and deposit at the atheromatous plaque, and second, at an insufficient concentration of multifactorial type of high density lipoprotein-cholesterol (HDL-c), whose function is to protect against the development of atherosclerosis. Its highest prevalence is encountered among individuals with diabetes, hypertension or overweight. Hyperlipidemia is one of the main predisposing factors for the development of cardiovascular disease. Hyperlipidemia can be the result of a genetic condition, the secondary expression of a primary process or the consequence of exogenous factors (food, cultural, socio-economic, etc.), all of which lead to the elevation of plasma lipid levels. The objective of this study was to carry out an analysis of the genes involved in the development of dyslipidemias that lead to cardiovascular disease with special emphasis on the proprotein convertase subtilin/kexin type 9 (PCSK9) gene. The PCSK9 gene participates in the development of primary dyslipidemias, mainly familial hypercholesterolemia, currently the pharmacological treatment of choice to reduce LDL-c are statins, however, it has been observed that these have been insufficient to eliminate cardiovascular risk, especially in subjects with primary forms of hypercholesterolemia related to genetic mutations, or statin intolerance.
Comparative analysis of genes associated with obesity in humans using bioinformatic data and tools
Authors: Musliji ZS , Pollozhani AK , Lisichkov K , Deligios M , Popovski ZT 
Published: July 2021

Abstract
Obesity has become a serious global problem that still needs a solution. One of the factors that leads to obesity is genetic predisposition. The identity and characteristics of the genes involved have not yet been fully confirmed. Analyzing the genetic contribution to obesity is a major step towards the solution. In this in silico study, using online bioinformatics tools, we evaluate the role of four genes that are believed to contribute to obesity. Data were collected and analyzed for the sequences of four so-called obesity genes: FTO (fat mass and obesity-associated protein), PPARG (peroxisome proliferator activated receptor γ), ADRB3 (adrenergic receptor β 3) and FABP2 (fatty acid binding protein 2). In the first part of the research, information about the genes was collected and organized and data in FASTA, format are extracted from the National Center for Biotechnology Information (NCBI). In the second part, all genes were analyzed by comparing three species of organisms, Homo sapiens (human), Mus musculus (mouse) and Gallus (chicken). In the third part of this study, phylogenetic trees were constructed for each of the four genes, using blast local alignment search tool (BLAST) and molecular evolutionary genetics analysis (MEGA X) software. Our analysis reveals that the functions of all these genes are associated with overweight and obesity.
A case of glycogen storage disease type 1a mimicking familial chylomicronemia syndrome
Authors: Olgac A , Okur İ , Biberoğlu G , Ezgü FS , Tümer L 
Published: July 2021

Abstract
Glycogen storage disease type 1a (GSD1a) is an autosomal recessively inherited inborn error of metabolism caused by a mutation in the G6PC gene, which encodes the catalytic subunit of glucose-6-phosphatase-α (G6Pase-α) enzyme. This enzyme plays a role in the final step of gluconeogenesis and glycogenolysis. Patients carrying GSD1a show growth retardation, hypoglycemia, hepatomegaly, hepatic steatosis, hyperlipidemia, hyperuricemia and lactic acidemia. Long-term symptoms include gouty arthritis and uric acid stones, osteoporosis, renal failure, intestinal impairment, cirrhosis and hepatic adenomas, and eventually, hepatocellular carcinoma. Hyperlipidemia is the indicator of poor metabolic control in GSD1a. Patients with variable levels of triglycerides (TGs) have been reported in the literature. We present a case of GSD1a that presented with severe hypertriglyceridemia (HTG) mimicking familial chylomicronemia syndrome.
Trade Fair Fee as a Source of Income for the Budgets of Municipalities in Poland on Selected Examples
Authors: Szydłowski Cezary 
Published: July 2021

Abstract
The public finance system in force in Poland provides for a trade fair fee (Polish - „opłata targowa”) as part of municipalities’ own revenues. The trade fair fee is collected from persons selling at marketplaces located in the municipality. It constitutes own income for the commune’s budget and is an archaic form of public tribute. According to the legal regulations in force in Poland, communes may waive the collection of the exhibition fee, however, there are still many communes collecting it. The assessment of income to the commune budget from the trade fair fee was carried out on the basis of a survey of income to the budget of selected 10 coastal communes in Pomorskie Voivodeship. The selection of coastal municipalities was determined by their specificity in terms of retail trade on markets and squares. This is because the holiday season attracts many tourists and entrepreneurs who sell the goods they offer in the mode of direct retail trade carried out on local markets, streets or squares (often located near the entrance to local beaches). The analysis of income from the fair fee was carried out on the basis of reports on the implementation of the budgets of communes and reports on the income of communes Rb-27s published by commune authorities on the pages of the Public Information Bulletin of a given local government unit. Verification of the revenue of the selected 10 municipalities from the fair fee for 2016-2019 revealed a very low share of the fair fee in the total revenue to the municipalities’ budgets (maximum 1.60% for the Łeba municipality in 2016). Moreover, the communes incur significant costs related to the collection of the trade fair fee, which are connected with the payment of commissions on the collected amounts up to 25% of the total income from the fee.
The results of the research indicate that it would be reasonable for the authorities of the analysed communes to consider abolishing the trade fair fee in their area, as the revenue is small compared to the costs incurred.
The liquidation of the market fee may attract more traders and improve the image of the commune as a facilitator of business activities involving trade in marketplaces.
Do Fiscal Transfers Foster Regional Economic Growth?
Authors: Mose Naftaly 
Published: July 2021

Abstract
Fiscal transfer development across the world today has been in part driven by assertions of a supposed ‘economic dividend’ linked with the devolved financial spending. There is, however, little empirical evidence to validate these assertions in Kenya. It is against this background that this study was carried out to estimate the end product of fiscal transfer on regional economic growth in Kenya using a secondary panel data set. Using the ARDL estimation technique the long -run and error correction estimates of the model were generated. The findings revealed that increased fiscal transfer in recurrent budgets accelerates regional growth, hence confirming the Keynesian hypothesis. Conversely, fiscal transfer in capital expenditure was insignificant. This study recommends the need for policymakers to put in place policies and strategies that will improve budget allocation and execution in capital budgets so as to improve physical infrastructure and thus boost private productivity and consequently regional income growth.
The Use of Digital Technology Platforms in the Context of Cybersecurity in the Industrial Sector
Authors: Bartczak Krzysztof 
Published: July 2021

Abstract
This study discusses the use of digital technology platforms (DTPs) in the context of cyber-security in the industrial sector, with a focus on digital industry (industrial) platforms (DIPs). A definition of DTPs is presented, including the author's interpretation, as well as the scope of DTP application in the industrial sector, which includes, in particular, European Digital Platforms (EDPs) and Polish Digital Platforms (PDPs), such as non-ferrous metals PDP or intelligent transport systems PDP. This is followed by a section covering the theoretical basis of the study that highlights the key challenges and risks associated with the use of DTPs as well as the methods for their neutralization in the form of specific concepts and systems that can be employed in the industrial sector. The subsequent section of the study is based on results of the author's own survey which collected information from a total of 120 companies operating in Poland, which were granted subsidies under the Operational Program Innovative Economy for investments involving the implementation and development of DTPs. The survey was carried out using a questionnaire developed by the author, which consisted of 23 questions. In this respect, as shown by the author's own studies, of greatest relevance are hardware failures and Internet outage events. Most importantly, concerns about such risks are some of the major factors underlying the negative attitudes of management staff of industrial companies toward DTPs, and therefore, it is so important to ensure that any such risks can be effectively addressed. They can be avoided through the use of certain concepts and systems such as STOE or CVSS. A typical company may know the model of DTPs in the context of challenges in the field of cybersecurity through this study; in particular, it can improve IT security.
المجلس المفقود في الفيدرالية العراقية
Authors: Kiro Ibrahim Ali 
Published: July 2021

إن كل الفيدراليات نشأة كحل للخلافات بين التكتلات القومية والدينية ، واللغوية ، والمصالح داخل الدول في المجتمعات التعددية هنالك أكثر من 25 فيدرالية ناجحة في العالم .
وتقوم الفيدرالية على مبدأين أساسيين ، هما مبدأ المشاركة في الحكومة الاتحادية ومبدأ الاستقلال الذاتي في الولايات أو الأقاليم الداخلة في الاتحاد ، وضمان نجاح هذه الفيدراليات بفاعلية هي المجلس الاتحادي ، أما في حالة الفيدرالية العراقية نلاحظ الغياب التام لهذا المجلس .
PROFESSIONAL SELF-DETERMINATION OF HIGH SCHOOL STUDENTS WITH DIFFERENT DEGREES OF REFLEXIVITY
Authors: Кудинов Сергей Иванович , Кудинов Станислав Сергеевич , Кудинов Владислав Сергеевич , Достатняя Александра Андреевна 
Published: July 2021

Анализируется рефлексивность как основа самопознания и понимания себя субъектом в будущей профессиональной деятельности. Проанализированы психологические особенности профессионального становления личности в юношеском возрасте, рассмотрена специфика проявления рефлективности, выделены уровни ее развития и определена роль в профессиональном самоопределении старшеклассников. Эмпирическое исследование проведено на выборке 244 учащихся (136 девушек и 108 юношей, средний возраст - 16 лет). В исследовании были использованы: тест на выявление профессионального типа личности Дж. Холанда в модификации (Г.В. Резапкиной); методика «Мотивы выбора профессии» Г. Овчаровой; методика определения уровней развития рефлексивности А. Карпова; методика «Дифференциальный тип рефлексии» Д.А. Леонтьева и эссе на тему «Роль прошлого, настоящего и будущего в моей жизни». По результатам пилотажного этапа исследования выделены три группы респондентов с разными показателями рефлексивности. Количественный и качественный анализ показателей рефлексивности и профессионального самоопределения старшеклассников позволил установить специфическое соотношение указанных характеристик. Результаты исследования могут стать основой для развития рефлексивности старшеклассников и для создания программ актуализации их профессионального самоопределения.
The analyzes reflexivity as the basis of self-knowledge and understanding of oneself as a subject in future professional activity. The psychological features of the professional formation of a personality in the youth age were analyzed, the specifics of the manifestation of reflexivity were considered, the levels of its development were singled out and the role in the professional self-determination of high school students was defined. An empirical study was carried out on a sample of 244 students (136 girls and 108 boys, average age - 16 years). In the empirical study, the following were used: the test to identify the professional type of personality of J. Holand in a modification (G.V. Rezapkina); the method «Motives for Choosing a Profession» by G. Ovcharova; Karpov's method to determine the levels of development of reflexivity; the technique «Differential Type of Reflexion» by D.A. Leontiev and the essay «The Role of the Past, Present, and Future in My Life». In the course of the empirical study, three groups of respondents with different indicators of reflexivity were identified. The quantitative and qualitative analysis of the indexes of reflexivity and professional self-determination of high school students allowed us to establish a specific correlation of these characteristics. The results of the research can become the basis both for the development of the reflexivity of high school students and for the creation of programs to actualize their professional self-determination.
Geograficidade e vulnerabilidades na Amazônia ribeirinha, comunidade Xixuaú, Roraima, Brasil
Authors: Veras Antonio Tolrino de Rezende , Santos Eder Rodrigues , Leal Rubens Savaris 
Published: July 2021

O texto analisa a geograficidade e as vulnerabilidades percebidas na comunidade de Xixuaú, localizada Ã s margens do rio Jauaperi, região do Baixo Rio Branco, em Roraima, extremo norte amazônico. Para isso, busca na pesquisa de campo e na bibliografia de filiação fenomenológica, compreender a ideia de lugar, lançando mão das narrativas dos moradores sobre seu modo de vida e a relação histórica deste ser ribeirinho com o espaço vivido. Nota-se que o ribeirinho amazônico tem uma cosmologia particular multidimensional do ambiente, demonstrando que é possível adequar-se Ã s verticalidades de interesse econômico, mas ao mesmo tempo, resistir a tais intervenções externas, se preciso, na defesa do lugar.
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ANALYSIS OF PRINCIPLE DIMENSION AND SHAPE OF PURSE SEINERS IN AMBON ISLAND
Authors: Lainsamputty Helly S 
Published: July 2021

Abstrak Purse seiners as a ship's main small pelagic fish Catcher is increasingly growing in number and size. In the last 5 years has been an increase in purse seine boats in Maluku by 20% and 15% of the overall operating in waters around the island of Ambon. Purse seiners tend to be made traditionally based on experience and not in accordance with the criteria of size comparison of a fish boat. It is very technical and operational feasibility of affect in this speed, stability and longitudinal strength . This research aims to calculate speed, tonnage (GT), the size of the principal as well as set the geometric shapes of purse seiners on the island of Ambon. The methods used in this research is a survey method by gathering primary and secondary data by making observations and measurements directly against the 32 purse seiners in Ambon island. Analysis and discussion is done through estimation the ship's speed by using the formula of Nomura, estimated tonnage (GT) using the Standard Fish Vessel Regulations by the Director-General of Fisheries Catch of Indonesia in 2004, the determination of the optimal size of the principal ship in the empirical formula by numerical – Traung and geometric forms of purse seiner . Estimation against speed (V) and the tonnage (GT) shows that the speed average (Vaverage) = 7.1 knots and tonnage average(GTaverage) = 22.4 tons. The calculation of the size of the principal ship by using empirical methods-numerical based on Traung equation with input of Vaverage and GTaverageindicates that the principal dimension is as follows: LBP = 15.8 meters; B = 4.8 meters; D = 2.2 meters and d = 1.9 meters and form coefficient as follows : CB = 0,6 ; CW = 0,7 ; CM = 0,97 ; CP = 0,62