bluuebunny/crossref_metadata_2025_split huggingface dataset:
ENO receives standing ovation for employee engagement
Authors: Cattermole Gary 
Published: August 2021

Purpose
The purpose of this paper is to focus on cultural change and how to boost employee engagement for employees in the arts.

Design/methodology/approach
The research consisted of employee surveys, focus groups as well as in depth evaluation and analysis with the senior management team to bring about cultural change in the organisation.

Findings
The results were extremely impressive with 91% of all employees agreeing that they understand the organisation's culture and values and would recommend the ENO as a place to work.

Originality/value
The ENO is an internationally renowned centre for live performance. This work demonstrates how an organisation can bring people together from a vast range of backgrounds, skillsets to become a cohesive and highly engaged team.
Business success in the platform economy depends on the right ecosystem strategy and execution
Authors: Pooya Golnar , Cheng Nathan , Marshall Anthony , Dencik Jacob , Agrawal Namit 
Published: August 2021

Purpose
Ecosystems’ digitally enabled networks that enhance corporate value propositions by linking corporate units, suppliers, distributors, partners, customers and other stakeholders -- have become the engine that drives performance and strategic impact across economies. Article examines which ecosystem strategies are appropriate for firms in various situations.

Design/methodology/approach
A new IBM Institute for Business Value (IBV) survey of 700 executives involved in decision-making about their organizations’ ecosystem growth and partnering reveals that the companies most focused on ecosystem engagement consistently generate higher growth and more business value.

Findings
Analysis of the executive responses identified four distinct strategic approaches for ecosystem activity – Accelerate, Expand, Ignite and Reposition.

Practical/implications
Success is likely only if firms pursue the right ecosystem strategy for their situation, with the right business partners, executed the right way.

Originality/value
Ecosystems can enhance the value of products or services through both competition and cooperation with partners and rivals. For enterprises battling dislocation and disruption, ecosystems promote agility and resilience and can identify new revenue opportunities. As such, ecosystems have been the essential vehicle for growth and expansion for many corporations.
A reprise of TQM practices among construction enterprises in Nigeria
Authors: Babatunde Oluwayomi Kayode 
Published: August 2021

PurposeStudies on total quality management (TQM) implementation among construction enterprises in Nigeria have used few TQM constructs and variables and yielded fragmented results. This study adopts comprehensive TQM constructs and variables for comparison with the previous studies to establish the critical variables for effective TQM practices in Nigeria.Design/methodology/approachData collection from a stratified sample of Nigerian construction practitioners with practical or theoretical knowledge of TQM, using web-based questionnaires consisting of twelve validated TQM implementation constructs and 65 variables. 72 home and overseas practicing professionals participated (21% response rate) using nonprobability sampling techniques. Following acceptable Cronbach's alpha reliability values equal to 0.7, the author/s rank-ordered the twelve TQM constructs and 65 TQM variables. Then, they computed the z-scores and the percentiles to identify the TQM critical variables – 75th percentiles and above, contrasted with the threshold normalized values equal to 0.5. Furthermore, Pareto analysis determined the 20% “vital many” responsible for 80% of the problem.FindingsCustomer focus, top management commitment and supplier quality management were the top-25% constructs, while employee involvement, statistical process control and design quality management were the bottom-25% constructs. Thirteen TQM critical variables emerged from the top-25% constructs.Practical implicationsTop management to involve employees to be customer-focused and driven toward suppliers' quality management system. Priority should be given to implementing the critical variables advanced in this study.Originality/valueThis study juxtaposes the results of similar studies for consistency to advance the critical success factors.
Technology and leadership styles: a review of trends between 2003 and 2021
Authors: Dhamija Pavitra , Chiarini Andrea , Shapla Shara 
Published: August 2021

PurposeLeadership style denotes the behavioural pattern of a leader, which bears on employee's attitude, perception about organization, manager and job satisfaction. The existence of different styles has presented leadership from diverse perspectives related to individuals' personality and behaviour. The main objective of this article is to explore the association between leadership styles and technology, major themes in this area and what can be the future research directions of this work.Design/methodology/approachLeadership style denotes the behavioural pattern of leader, which bears on employee's attitude, perception about organization, manager and job satisfaction. The existence of different styles has presented leadership from diverse perspectives related to individuals' personality and behaviour. The present article aims to review significant work by eminent researchers towards technology and leadership styles in the form trends, annual scientific production; popular affiliations and sources, a three-field plot of countries, scholars and themes, most cited references, trending keywords, thematic analysis of leadership styles and technology research by taking insights from situational leadership theory.FindingsThe findings indicate connections between various keywords and provide interesting themes like transformational leadership style is connected to knowledge management, transactional leadership, empowering leadership, psychological capital and e-leadership. Similarly, leadership is connected to leadership development, gender stereotypes, emotional exhaustion, innovative leadership and organizational performance.Originality/valueThis review analysis of leadership styles and technology is in itself a novice contribution and first of its nature. The identified themes are presenting good knowledge and food for thought for future researches.
Future perspectives on progressive farming with adoption of virtual reality technology for sustainable quality in agriculture
Authors: Kumari Sneha , Raghuram P. , Venkatesh V.G. , Shi Yangyan 
Published: August 2021

PurposeThe paper aims to evaluate how progressive stakeholders view the adoption of contemporary techniques such as virtual technology in driving sustainable quality in an emerging economy context.Design/methodology/approachThe authors adopted a systematic literature review to develop the theoretical framework for virtual reality (VR) technology adoption in sustaining quality in agriculture production. The framework was refined after discussion with a panel of academic experts. The refined theoretical framework was further empirically validated using Partial Least Square Structure Equation Modelling.FindingsThe study focuses on the future perspective of the perception for progressive farming with the adoption of VR technology in an emerging economy. The data were collected from the stakeholders (farmers, collectives, cooperative, etc.), for their future perspectives for the adoption of VR technology and sustainable quality agriculture production. The study may help build up VR technology in emerging economies which may take years to be established.Research limitations/implicationsThe perception of the future perspective of VR technology study conducted has limitations. The findings are well established on technology adoption; however, the technology used will take many extra years to find its application in the agriculture sector. The study offers insightful theoretical, managerial and policy implications for sustainable quality in agriculture production through the adoption of virtual reality (VR) technology. The authors found very few works that focused on VR technology adoption.Originality/valueThe study discusses VR, which has an impact on sustaining the quality of agriculture production. The study has notable managerial and policy implications that suggest the future perspective for VR technology in agriculture production. The study is an unexplored area that needs research to capture future perspectives.
Numerical modeling of liquid sloshing in flexible tank with FSI approach
Authors: Khouf Lydia , Benaouicha Mustapha , Seghir Abdelghani , Guillou Sylvain 
Published: August 2021

Purpose
The paper aims to present a numerical modeling procedure for the analysis of liquid sloshing in a flexible tank subjected to an external excitation, with taking into account the effects of fluid–structure interaction (FSI).

Design/methodology/approach
A numerical model based on coupling a two-phase flow solver and an elastic solid solver is developed in OpenFOAM code. The Arbitrary Lagrangian–Eulerian formulation is adopted for the two-phase Navier–Stokes equations in a moving domain. The volume of fluid (VOF) method is applied for the air–liquid interface tracking. The finite volume method is used for the spatial discretization of both the fluid and the structure dynamics equations. The FSI coupling problem is solved by an explicit coupling scheme. The model is validated for linear and nonlinear sloshing cases. Then, it is used to analyze the effects of the liquid sloshing on the dynamic response of the tank and the effects of the tank flexibility on the liquid sloshing.

Findings
The obtained results show that the flexibility of the tank walls amplifies the amplitude of the sloshing and increases the fluctuation period of the air–liquid interface. Furthermore, it is found that the bending moment acting on the tank walls may be underestimated when rigid walls assumption is adopted as usually done in sloshing tank modeling. Also, tank walls flexibility causes a phase shift in the free surface dynamic response.

Originality/value
A review of previous studies on liquid sloshing in flexible tanks revealed that FSI effects have not been clearly and comprehensively analyzed for large-amplitude liquid sloshing. Many physical and numerical aspects of this problem still require clarifications and enhancements. The added value of the present work and its originality lie in the investigation of large-amplitude liquid sloshing in flexible tanks by using a staggered coupling approach. This approach is carried out by an original combination of a linear solid solver with a two phase fluid solver in OpenFOAM code. In addition, FSI effects on some response quantities, identified and analyzed herein, have not been found in the previous works.
Diversity begets diversity: Low resource heterogeneity reduces the diversity of nut‐nesting ants in rubber plantations
Authors: Miao Bai‐Ge , Peng Yan‐Qiong , Yang Da‐Rong , Guénard Benoit , Liu Cong 
Published: August 2021

AbstractOne of the most general patterns in ecology is the positive relationship between environmental heterogeneity and local diversity. On the one hand, increased resource heterogeneity provides more resources for diverse consumers in the community. On the other hand, increased structural heterogeneity creates variation in the environment's physical structure, thus allowing the coexistence of diverse species with different environmental requirements. Here, we examined the relative importance of resource and structural heterogeneity in determining the taxonomic, functional, and phylogenetic diversity of nut‐nesting ants in natural rainforest and rubber plantation. The species richness of nut‐nesting ants was 70% higher in rainforest than in rubber plantation. The clustered functional and phylogenetic structure in rubber plantation suggested a strong effect of environmental filtering in shaping ant functional and phylogenetic structure. Nesting heterogeneity (nut diversity) was the major factor explaining variation in taxonomic, functional, and phylogenetic diversity, suggesting that resource heterogeneity plays a major role in shaping the biodiversity patterns of nut‐nesting ants. Overall, these results indicate that decreased resource diversity following the conversion of rainforest to rubber plantation can drive biodiversity loss in nut‐nesting ants, through its effect on reducing both ant species, functional, and phylogenetic diversity. The decline in species richness and functional and phylogenetic diversity in the local ant community might have major effects on ecosystem functioning.
Arabis alpina: A perennial model plant for ecological genomics and life‐history evolution
Authors: Wötzel Stefan , Andrello Marco , Albani Maria C. , Koch Marcus A. , Coupland George , Gugerli Felix 
Published: August 2021

AbstractMany model organisms were chosen and achieved prominence because of an advantageous combination of their life‐history characteristics, genetic properties and also practical considerations. Discoveries made in Arabidopsis thaliana, the most renowned noncrop plant model species, have markedly stimulated studies in other species with different biology. Within the family Brassicaceae, the arctic–alpine Arabis alpina has become a model complementary to Arabidopsis thaliana to study the evolution of life‐history traits, such as perenniality, and ecological genomics in harsh environments. In this review, we provide an overview of the properties that facilitated the rapid emergence of A. alpina as a plant model. We summarize the evolutionary history of A. alpina, including genomic aspects, the diversification of its mating system and demographic properties, and we discuss recent progress in the molecular dissection of developmental traits that are related to its perennial life history and environmental adaptation. From this published knowledge, we derive open questions that might inspire future research in A. alpina, other Brassicaceae species or more distantly related plant families.
Tumor‐associated macrophages (TAMs)‐derived osteopontin (OPN) upregulatesPD‐L1expression and predicts poor prognosis in non‐small cell lung cancer (NSCLC)
Authors: Li Yue , Liu Hailin , Zhao Yujie , Yue Dongsheng , Chen Chen , Li Chenguang , Zhang Zhenfa , Wang Changli 
Published: August 2021

AbstractBackgroundProgrammed cell death ligand 1 (PD‐L1) is widely known as an immune checkpoint molecule in tumor cells. Osteopontin (OPN) is expressed by both tumor cells and tumor‐associated macrophages (TAMs), and both autocrine and paracrine of OPN are considered to be involved in tumor metastasis, proliferation and immunosuppression. However, little is known about the relationship between OPN expressed in TAMs (TOPN) and PD‐L1 in non‐small cell lung cancer (NSCLC).MethodsTissue microarray was used to detect the expression of TOPN, TAMs and PD‐L1 by multiple quantitative fluorescence staining in 509 NSCLC patients undergoing complete pulmonary resection. The correlations between TOPN, PD‐L1 and clinicopathological data were analyzed. An in vitro coculture system was established to investigate the crosstalk between TOPN and neoplastic PD‐L1. In vivo, the intrinsic features of PD‐L1 in NSCLC xenografts were evaluated after being coinjected with OPN‐positive TAMs, and a series of key cytokines and chemokines were detected in the tumor microenvironment.ResultsA positive association between the TOPN and PD‐L1 expression in tumor tissues from 509 patients with NSCLC was verified. In addition, TOPN and PD‐L1 were independent prognostic factors for overall survival (OS) and disease‐free survival (DFS) of NSCLC patients. Moreover, TOPN upregulated PD‐L1 expression in NSCLC cells through the nuclear factor‐κB (NF‐κB) pathway in vitro TOPN induced the PD‐L1 expression promoted the tumor growth in tumor‐bearing mice, altering immune‐related cytokines and chemokines.ConclusionsTOPN regulates PD‐L1 expression through the NF‐κB pathway in NSCLS, which is a potential independent biomarker and target for prognosis as well as immunotherapy.
Dextran‐based priming solution during cardiopulmonary bypass attenuates renal tubular injury—A secondary analysis of randomized controlled trial in adult cardiac surgery patients
Authors: Kolsrud Oscar , Barbu Mikael , Dellgren Göran , Björk Kerstin , Corderfeldt Anna , Thoren Anders , Jeppsson Anders , Ricksten Sven‐Erik 
Published: August 2021

AbstractBackgroundAcute kidney injury (AKI) is a well‐known complication after cardiac surgery and cardiopulmonary bypass (CPB). In the present secondary analysis of a blinded randomized controlled trial, we evaluated the effects of a colloid‐based versus a conventional crystalloid‐based prime on tubular injury and postoperative renal function in patients undergoing cardiac surgery with CPB.MethodsEighty‐four adult patients undergoing cardiac surgery with CPB were randomized to receive either a crystalloid‐ or colloid‐ (dextran 40) based CPB priming solution. The crystalloid solution was based on Ringer‐Acetate plus mannitol. The tubular injury biomarker, N‐acetyl‐b‐D‐glucosaminidase (NAG), serum creatinine and diuresis were measured before, during and after CPB. The incidence of AKI was assessed according to the KDIGO criteria.ResultsThe urinary‐NAG/urinary‐creatinine ratio rose in both groups during and after CPB, with a more pronounced increase in the crystalloid group (p = .038). One hour after CPB, the urinary‐NAG/urinary‐creatinine ratio was 88% higher in the crystalloid group (4.7 ± 6.3 vs. 2.5 ± 2.7, p = .045). Patients that received the dextran 40‐based priming solution had a significantly lower intraoperative diuresis (p < .001) compared to the crystalloid group. The incidence of AKI was 18% in the colloid and 22% in the crystalloid group (p = .66). Postoperative serum creatinine did not differ between groups.ConclusionsIn patients undergoing cardiac surgery with CPB, colloid‐based priming solution (dextran 40) induced less renal tubular injury compared to a crystalloid‐based priming solution. Whether a colloid‐based priming solution will improve renal outcome in high‐risk cardiac surgery, or not, needs to be evaluated in future studies on higher risk cardiac surgery patients.
Oxygenation targets in ICU patients with COVID‐19: A post hoc subgroup analysis of the HOT‐ICU trial
Authors: Rasmussen Bodil S. , Klitgaard Thomas L. , Perner Anders , Brand Björn A. , Hildebrandt Thomas , Siegemund Martin , Hollinger Alexa , Aagaard Søren R. , Bestle Morten H. , Marcussen Klaus V. , Brøchner Anne C. , Sølling Christoffer G. , Poulsen Lone M. , Laake Jon H. , Aslam Tayyba N. , Bäcklund Minna , Okkonen Marjatta , Morgan Matthew , Sharman Mike , Lange Theis , Wetterslev Jørn , Schjørring Olav L. 
Published: August 2021

AbstractBackgroundSupplemental oxygen is the key intervention for severe and critical COVID‐19 patients. With the unstable supplies of oxygen in many countries, it is important to define the lowest safe dosage.MethodsIn spring 2020, 110 COVID‐19 patients were enrolled as part of the Handling Oxygenation Targets in the ICU trial (HOT‐ICU). Patients were allocated within 12 h of ICU admission. Oxygen therapy was titrated to a partial pressure of arterial oxygen (PaO2) of 8 kPa (lower oxygenation group) or a PaO2 of 12 kPa (higher oxygenation group) during ICU stay up to 90 days. We report key outcomes at 90 days for the subgroup of COVID‐19 patients.ResultsAt 90 days, 22 of 54 patients (40.7%) in the lower oxygenation group and 23 of 55 patients (41.8%) in the higher oxygenation group had died (adjusted risk ratio: 0.87; 95% confidence interval, 0.58–1.32). The percentage of days alive without life support was significantly higher in the lower oxygenation group (p = 0.03). The numbers of severe ischemic events were low with no difference between the two groups. Proning and inhaled vasodilators were used more frequently, and the positive end‐expiratory pressure was higher in the higher oxygenation group. Tests for interactions with the results of the remaining HOT‐ICU population were insignificant.ConclusionsTargeting a PaO2 of 8 kPa may be beneficial in ICU patients with COVID‐19. These results come with uncertainty due to the low number of patients in this unplanned subgroup analysis, and insignificant tests for interaction with the main HOT‐ICU trial.Trial registration number: ClinicalTrials.gov number, NCT03174002.Date of registration: June 2, 2017.
Increased Toll‐like Receptor‐MyD88‐NFκB‐Proinflammatory neuroimmune signaling in the orbitofrontal cortex of humans with alcohol use disorder
Authors: Vetreno Ryan P. , Qin Liya , Coleman Leon G. , Crews Fulton T. 
Published: August 2021

AbstractBackgroundMany brain disorders, including alcohol use disorder (AUD), are associated with induction of multiple proinflammatory genes. One aspect of proinflammatory signaling is progressive increases in expression across cells and induction of other innate immune genes. High‐mobility group box 1 (HMGB1) heteromers contribute to amplification by potentiating multiple proinflammatory responses, including Toll‐like receptors (TLRs). TLR signaling recruits coupling proteins linked to nuclear transcription factors that induce proinflammatory cytokines and chemokines and their respective receptors. We tested the hypothesis that AUD induction of TLR expression increases levels of proinflammatory genes and cellular signaling cascades in association with neurodegeneration in the orbitofrontal cortex (OFC).MethodsPostmortem human OFC tissue samples (n = 10) from males diagnosed with AUD were compared to age‐matched moderate drinking controls (CON). Neuroimmune signaling molecules were assessed using immunohistochemistry for protein and reverse transcription polymerase chain reaction for messenger RNA (mRNA).ResultsIn the AUD OFC, we report induction of the endogenous TLR agonist HMGB1 as well as all TLRs assessed (i.e., TLR2‐TLR9) except TLR1. This was accompanied by increased expression of the TLR adaptor protein myeloid differentiation primary response 88 (MyD88), activation of the proinflammatory nuclear transcription factor nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NFκB), and downstream induction of proinflammatory cytokines, chemokines, and their corresponding receptors. Several of these proinflammatory signaling markers are expressed in glia and neurons. The induction of HMGB1‐TLR‐MyD88‐NFκB proinflammatory signaling pathways correlates with neurodegeneration (i.e., Fluoro‐Jade B), lifetime alcohol consumption, and age of drinking onset.ConclusionThese data implicate the induction of HMGB1‐TLR‐MyD88‐NFκB cascades through coordinated glial and neuronal signaling as contributors to the neurodegeneration seen in the postmortem human OFC of individuals with AUD.