bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rhabdonatronobacter Sediminivivens gen. nov., sp. nov. Isolated from the Sediment of Hutong Qagan Soda Lake
Authors: Zhou Heng , Yang Ming , Xue Qiong , Zhang Shengjie , Zhou Jian , Zhao Dahe , Xiang Hua 
Published: May 2021

Abstract
A novel Gram-stain negative bacterium, designated IM2376T, was isolated from the sediment of Hutong Qagan Lake in Ordos, Inner Mongolia Autonomous Region of China. The strain IM2376T had the highest similarity with Roseinatronobacter thiooxidans DSM 13087T (96.18%) and Rhodobaca bogoriensis LBB1T (96.18%) of the family Rhodobacteraceae according to 16S rRNA gene sequence comparison. Genomic relatedness analyses showed that strain IM2376T was clearly distinguished from other species in the family Rhodobacteraceae, with average nucleotide identities, amino acid identities and in silico DNA-DNA hybridization values not more than 74.1%, 68.5% and 20.2%. The fatty acid was mainly composed of C18:1ω7c (64.86%), iso-C16:0 (16.33%) and C16: 1ω7c/C16:1ω6c (6.02%). The major polar lipid was diphosphatidyl glycerol, phosphatidylglycerol and phosphatidylcholine. The predominant ubiquinone was Q-10 (94.9%) and Q-11 (5.1%). The DNA G + C was 66 mol%. Based on all these results, strain IM2376T was considered to be a novel species of a new genus in the family Rhodobacteraceae, for which the name Rhabdonatronobacter sediminivivens gen. nov., sp. nov. is proposed. The type strain is IM2376T (= CGMCC 1.17852T).
Longitudinal Analysis of the Patient Pathways to Diagnosis of Psoriatic Arthritis
Authors: Ogdie Alexis , Rozycki Martin , Arndt Theresa , Shi Cheng , Kim Nina , Hur Peter 
Published: May 2021

Abstract
Background: The occurrence of health events preceding a psoriatic arthritis (PsA) diagnosis may serve as predictors of diagnosis. We sought to assess patients’ real-world experiences in obtaining a PsA diagnosis. Methods: This retrospective cohort study analyzed MarketScan claims data from January 2006 to April 2019. Included were adult patients with ≥2 PsA diagnoses (ICD-9-CM/ICD-10-CM) ≥30 days apart with ≥6 years of continuous enrolment before PsA diagnosis. Controls were matched 2:1 to patients with PsA. Health events (diagnoses and provider types) were analyzed before PsA diagnosis and additionally stratified by presence of psoriasis.Results: Of 13,661 patients, those with PsA had an increased history of coding for arthritis and dermatologic issues (osteoarthritis [48% vs 22%], rheumatoid arthritis [18% vs 2%], and psoriasis [61% vs 2%]) vs those without PsA. Diagnoses of arthritis, axial symptoms, and tendonitis/enthesitis increased over time preceding PsA diagnosis; notably, a sharp rise in psoriasis diagnoses was observed 6 months before PsA diagnosis. Rheumatology consults were more common immediately preceding a PsA diagnosis. Dermatologists were unlikely to code for arthritis and musculoskeletal issues, while rheumatologists were unlikely to code for psoriasis; general practitioners focused on axial and musculoskeletal symptoms. PsA was most commonly diagnosed by rheumatologists (40%), general practitioners (22%), and dermatologists (7%).Conclusions: Rheumatologists, general practitioners, and dermatologists diagnosed two-thirds of patients with PsA. Musculoskeletal symptoms were common preceding a PsA diagnosis. Greater awareness of patterns of health events may alert healthcare providers to suspect a diagnosis of PsA.
Sonochemical Synthesis of the Novel 1d Zig-zag Hg(Ii)-iodo Brigdged Metal-organic Coordination Compounds With Thiosemicarbazide Derivative Ligand
Authors: Hanifehpour Younes , Dadashi Jaber , Khaleghian Mohammad , Rezaei Mahboube , Mirtamizdoust Babak , Joo Sang Woo 
Published: May 2021

Abstract
In the present research, a novel mercury (II) metal organic coordination compound, [Hg(Q)I2]n (Q = pyridine-4-carbaldehyde thiosemicarbazide) with nano rods shape was prepared applying an ultrasonic manner. The synthesized compound was determined with infrared spectroscopy (IR), scanning electron microscopy (SEM), and X-ray diffraction (XRD). In solid state the coordination polymer takes the appearance of a zig-zag 1D polymer. The coordination number of Hg (II) is four by one sulfur atom of organic ligand and three iodine atoms which two of iodine atoms are coordinated to other repeating units, and one of iodine is unattached. The zig-zag 1D chains interact with neighboring chains via poor interactions, making a 3D supramolecular metal organic polymer.
The Role of Women's Traditional Gender Beliefs in Depression, Intimate Partner Violence and Stress: Insights from a Spanish Abbreviated Multicultural Measure
Authors: Rovira Montse , Lega Leonor , Suso-Ribera Carlos , Orue Izaskun 
Published: May 2021

Abstract
Background: Research on traditional gender beliefs has highlighted their psychological impact and social implications for women. The purpose of this study was two-fold: firstly, to explore the relationship between women’s traditional gender beliefs, intimate partner violence, stress and depression, and secondly, to adapt and validate the Spanish version of the Multicultural O’Kelly Women’s Beliefs Scale. Based on the Rational Emotive Behavior Therapy framework, traditional gender beliefs were expected to be associated with higher levels of intimate partner violence, stress and depression. We also expected to obtain a psychometrically-sound factor structure of the Multicultural O’Kelly Women’s Beliefs Scale.Methods: A sample of Spanish women (N=322) completed the Multicultural O’Kelly Women’s Beliefs Scale, the Beck’s Depression Inventory II, the Modified Conflict Tactics Scale, and the Stress Perceived Scale. To test the psychometric properties of the Multicultural O’Kelly women’s beliefs scale we implemented exploratory and confirmatory factor analyses and an analysis of the area under the curve.Results: Regarding the psychometric properties of the scale, statistical analysis revealed a one-factor dimensionality (Global traditionalism) and supported a reduction of items in the original instrument. The abbreviated version (eight items) obtained the best fit indices. Considering the association between traditional gender beliefs and psychological outcomes, we found that traditional gender beliefs were associated with increased severity of stress, depressive symptoms and reciprocal verbal aggression. Conclusion: The Spanish adaptation of the Multicultural O’Kelly women’s beliefs scale provided a very short, psychometrically robust and clinically relevant measure of traditional gender beliefs. In addition to the association between traditional gender beliefs and mental health outcomes, an important finding was the relationship between traditional gender beliefs and intimate partner violence. Our scale might be used in clinical settings by helping women to identify their traditional gender beliefs and replace them by healthy and goal–oriented beliefs, which would also contribute in achieving a more egalitarian society.
Two Interventions to Provide Support to Long-Term Care Facilities During the Covid-19 Pandemic
Authors: BOIXAREU CRISTINA BERMEJO , Ussía Macarena Díaz de Bustamante , Delgado Gema Piña , Gómez Armando Pardo , Arana Lucia Fernandez , Cárdenas Verónica García , Gómez-Pavón Javier 
Published: May 2021

Abstract
BACKGROUND
The aim of this article is to describe two interventions carried out during the first wave of the COVID19 pandemic to support healthcare personnel at 60 nursing homes, located within the coverage area of a 613-bed university tertiary care hospital.
METHODS
In the first intervention, a geriatrician provided telephone support, including help with the clinical management of residents, the administration of intravenous and/or hospital-based treatments, provision of oxygen therapy at the facility, blood and diagnostic tests, and the coordination of disinfection by the Military Emergency Unit. In the second intervention, the multidisciplinary care team also performed on-site visits to the nursing homes.
RESULTS
In the first telephone support intervention 4,553 cases were evaluated. Of these cases, 645 residents (14.2%) were given on-site intravenous therapy; 419 cases (9%) were prescribed oxygen therapy, and 573 nasopharyngeal exudate samples were tested (RT-PCR). In the second intervention, 4,965 residents were assessed on-site. Of these, intravenous treatment was prescribed in 316 patients (6.3% of cases) and oxygen therapy in 634 (12.7%). A total of 2.458 RT-PCR tests were performed on residents and workers. There was a decrease in the mortality rate ten days after the implementation of the second intervention.
CONCLUSIONS
Geriatrician-directed telephone support is a highly efficient and essential approach to coordinate long-distance healthcare delivery at nursing homes, but it doesn't seem to reduce mortality. Interventions, including multidisciplinary/Geriatrics visits in nursing homes during pandemics are needed to study if mortality rates can be reduced.
Numerical and Experimental Study on Curing-induced Residual Stress and Deformation of Adhesively Bonded Sandwich Structures of Dissimilar Materials
Authors: Li Jianjun , Zhu Wenfeng , Li Yuanhui , Tang Genglin 
Published: May 2021

Abstract
Adhesively bonded sandwich structure with dissimilar materials becomes an important means of lightweight for the next generation of autobody closure panels. However, during the baking process, the complicated change of physical properties of the adhesive can lead to structural mismatch deformation. In this paper, a multi-physics coupling numerical model of one-component hemming adhesive during the curing process is proposed, to reveal the deformation mechanism of adhesively bonded sandwich structures quantitatively. The material constitutive model of the hemming adhesive is established, considering evolution of curing properties. The curing process of typical aluminum alloy and steel bonded sandwich structure is simulated in COMSOL Multiphysics. The predicted surface deformation of the component is verified by experiment using Digital Image Correlation (DIC) technique, which captures the full-field displacement in a non-intrusive manner. Then, the development process of surface deformation of the outer panel and residual internal stress of the adhesive layer is analyzed, and the influence of temperature cycle on the maximum deformation of the component is discussed. The results show at the beginning of holding stage, the deformed component slightly rebounds, which is related to the chemical shrinkage. Mechanical strain caused by the coefficient of thermal expansion (CTE) and stiffness difference of the inner and outer panels is dominant in the adhesive layer. Reducing the curing rate and maximum holding temperature can reduce the overall deformation of the structure.
Self-care behavior and associated factors among patients with Type 2 Diabetes in Hossana, Southern Ethiopia: The Health Belief Model Perspective
Authors: Prakash Ravi , Abute Lonsako , Erchafo Belay , Tadesse Tegegn , Kedir Tirulo , Sedoro Tagesse , Tamirat Temesgen , Gizachew Addiselam 
Published: May 2021

Abstract
Background

Diabetes a chronic disease requires lifelong medical treatments and life-style adjustment. Hence, it requires dedication towards self-care behavior in multiple domains. We aimed to identify determinants of self-care behavior among patients with diabetes through Health Belief Model Perspective.
Methods

A cross-sectional study was conducted on 276 patients with simple random sampling technique. The level of self-care behavior on diabetic patients was measured using parameters of physical exercise, diet, medication and blood glucose. Bivariate and multivariable logistic regression analyses were conducted.
Results

Approximately, 119 (43.1%) of them practiced recommended self-care practices. Patients with more information performed 3 times more self-care (OR-3.07;95%CI 0.19–7.9) than less informed patients. Individuals with high income performed two times more self-care than less income (OR-2.42;95%CI 1.04–17.95). High perceived severity was 8 times more likely to performed for self-care than less perceived severity (OR-8.3,95%CI1.19-16.25).
Conclusion

Status of self-care practices on diabetic patients is lower than studies in other areas. Training should be focused on perceived severity of diabetes and how to overcome perceived barriers for self-care by increasing the frequency and reach out message on diabetes.
The Method and Results of a Treatment Targeting SARS-CoV-2-Activated Inflammasomes
Authors: LEE JONG HOON , Kanwar Badar , Khattak Asif , Balentine Jenny , Lee Chul Joong , Oh Sang-Suk 
Published: May 2021

Abstract
A COVID-19 committee at Hunt Regional Medical Center reviewed the use of dapsone as an inflammasome competitor. The hospital then revalidated its effectiveness by reporting the findings of 44 (22 cases/22 controls) patients with acute respiratory distress syndrome (ARDS) treated with dapsone. All of 17 ARDS Onset patients who received standard COVID-19 treatment, including dapsone, did not die except one patient not taken dapsone after relapsed, whereas 8/20 patients who received standard COVID-19 treatment without dapsone died; the mortality rates were 5.9% and 40%, respectively. Dapsone treats and prevents SARS-CoV-2 ARDS. We confirmed that dapsone clinically treated the onset of ARDS by targeting SARS-CoV-2-activated inflammasomes.
The Impact of Covid19 Pandemic, Financial Wellness, and Online Teaching on The Mental Health of Lebanese Schoolteachers
Authors: Baroud Tarek , Masri Jad El , Shammaa Hadi , Chanbour Hani , Eddine Issa Kamal , Salameh Pascale 
Published: May 2021

Abstract
The authors have requested that this preprint be removed from Research Square.
Mindful Eating Proficiency and Healthy Eating Literacy in Japanese Mothers: Associations with Their Own and Their Children’s Eating Behavior
Authors: Nakamura Taro , Yoshiike Nobuo 
Published: May 2021

Abstract
Purpose

Mindfulness is a psychological process that can be developed using meditation and other types of training to focus on the present moment. Applying this concept to eating (i.e., mindful eating; ME) is associated with regulated eating behavior, especially in overweight or obese people. Sustaining healthy eating habits requires both healthy eating literacy (HEL) and proficiency in ME. However, ME proficiency in Japanese people has not been sufficiently investigated.
Methods

We conducted a survey of mothers with 4 to 5-year-old children in Aomori City, Japan, to investigate their ME proficiency and HEL level, as well as eating behavior and self-reported body mass index in both mothers and their children. This study was the first to describe ME proficiency in Japanese mothers.
Results

ME proficiency in mothers was positively correlated with both their own and their children’s eating behaviors, suggesting a potential relationship, while strong relationships were not observed between the HEL level and eating behaviors of mothers and children.
Conclusion

Improving ME skills, rather than HEL, may be an effective way to sustain healthier eating behaviors in mothers and their children.
Level of evidence:

Level I, Evidence obtained from experimental studies
Effective health service planning and delivery: A qualitative case study exploring health service users perspectives
Authors: Marme Gigil 
Published: May 2021

Abstract
IntroductionHealthcare service is an essential determinant to population health. This qualitative case study aims to explore health service users’ perspective of effective health services delivery and the current challenges affecting the management and delivery of health services at a primary healthcare facility in Madang Province, Papua New Guinea (PNG).MethodsQualitative data were collected using semi-structured interviews with key informants (KI) representing academics, undergraduate students, administration staff, patients and healthcare workers. The interviews covered three main areas: users’ views of effective health services, current challenges affecting effective planning and management of primary healthcare services, and interventions to improve health services planning and delivery.ResultsThe services users associated effective health services delivery with increased availability, accessibility, acceptability, and quality healthcare. Many factors exist to influence the effective planning and delivery of health services. The results show that health systems and personal factors have a major influence on the planning and health services delivery.ConclusionThe findings from this study call for an evaluation of the current healthcare system, particularly at the primary healthcare level, as the primary point of contact to the formal healthcare system, and the need for developing a contextual model of healthcare that meet the needs of the service users. We concluded that if health services users’ perspectives are considered in health policy, the local community may experience significant improvement in health status.
Incorporating Medical Students Into Primary Care Telehealth Visits: Tutorial
Authors: Balaji Aanika , Clever Sarah Lou 
Published: May 2021

Background
The COVID-19 pandemic has brought about sweeping change in health care delivery, which has shifted from in-person consultations to a web-based format. Few medical schools provide web-based medicine or telemedicine training to their learners, though this is likely to be important for future medical practice.

Objective
This tutorial communicates a framework for incorporating medical students into primary care telemedicine clinics.

Methods
A third-year medical student and internal medicine attending physician from the Johns Hopkins University completed telemedicine clinic visits in April 2020 by using a variety of video platforms and via telephone calls.

Results
Nine telemedicine visits were completed over 4 clinic days. Our patients were, on average, aged 68 years. The majority of patients were female (6/9, 67%), and most appointments were completed via a video platform (6/9, 67%). Additionally, our experience is summarized and describe (1) practical tips for how to prepare for a telehealth visit; (2) technology considerations; (3) recommendations for participation during a telehealth visit; (4) debriefing and feedback; (5) challenges to care; and (6) student, care provider, and patient reactions to telemedicine visits.

Conclusions
Telemedicine clinics have been successfully used for managing patients with chronic conditions, those who have attended low-risk urgent care visits, and those with mental health concerns. Patients have reported high patient satisfaction scores for telemedicine visits, and the majority of patients are comfortable with having medical students as part of their care team. Moving forward, telemedicine will remain a popular method for receiving health care. This study has highlighted that medical students can successfully be integrated into telemedicine clinics and that they should be exposed to telehealth whenever possible prior to residency.
Evidence of Human-Level Bonds Established With a Digital Conversational Agent: Cross-sectional, Retrospective Observational Study
Authors: Darcy Alison , Daniels Jade , Salinger David , Wicks Paul , Robinson Athena 
Published: May 2021

Background
There are far more patients in mental distress than there is time available for mental health professionals to support them. Although digital tools may help mitigate this issue, critics have suggested that technological solutions that lack human empathy will prevent a bond or therapeutic alliance from being formed, thereby narrowing these solutions’ efficacy.

Objective
We aimed to investigate whether users of a cognitive behavioral therapy (CBT)–based conversational agent would report therapeutic bond levels that are similar to those in literature about other CBT modalities, including face-to-face therapy, group CBT, and other digital interventions that do not use a conversational agent.

Methods
A cross-sectional, retrospective study design was used to analyze aggregate, deidentified data from adult users who self-referred to a CBT-based, fully automated conversational agent (Woebot) between November 2019 and August 2020. Working alliance was measured with the Working Alliance Inventory-Short Revised (WAI-SR), and depression symptom status was assessed by using the 2-item Patient Health Questionnaire (PHQ-2). All measures were administered by the conversational agent in the mobile app. WAI-SR scores were compared to those in scientific literature abstracted from recent reviews.

Results
Data from 36,070 Woebot users were included in the analysis. Participants ranged in age from 18 to 78 years, and 57.48% (20,734/36,070) of participants reported that they were female. The mean PHQ-2 score was 3.03 (SD 1.79), and 54.67% (19,719/36,070) of users scored over the cutoff score of 3 for depression screening. Within 5 days of initial app use, the mean WAI-SR score was 3.36 (SD 0.8) and the mean bond subscale score was 3.8 (SD 1.0), which was comparable to those in recent studies from the literature on traditional, outpatient, individual CBT and group CBT (mean bond subscale scores of 4 and 3.8, respectively). PHQ-2 scores at baseline weakly correlated with bond scores (r=−0.04; P<.001); however, users with depression and those without depression had high bond scores of 3.45.

Conclusions
Although bonds are often presumed to be the exclusive domain of human therapeutic relationships, our findings challenge the notion that digital therapeutics are incapable of establishing a therapeutic bond with users. Future research might investigate the role of bonds as mediators of clinical outcomes, since boosting the engagement and efficacy of digital therapeutics could have major public health benefits.
Investigaciones geofísicas y características geoquímicas de las aguas hidrotermales: Volcán Poas, Costa Rica
Authors: Casertano L. , Borgia A. , Cigolini C. , Morales L. D. , Montero W. , Gomez M. , Fernandez J. F. 
Published: May 2021

Se relatan los resultados más importantes de las investigaciones geoquímicas y geofísicas llevadas a cabo en la caldera activa del volcán Poás en el trienio 1980-82. Las aguas de la laguna caliente manifiestan una fuerte acidez (pH <1) debida al elevado contenido de Cfy so;. También la concentración de los iones metálicos es muy alta. La temperatura (T • 229ºC) de la mezcla de las aguas freáticas con los fluidos calientes, calculada mediante los geotermómetros químicos está comprendida en el intervalo de las temperaturas medidas para las aguas geotermales asociadas con rocas andesíticas. El aumento de la temperatura desde 92ºC, en diciembre de 1980, hasta 960°C, durante el periodo marzo-noviembre de 1981, en el sector nor-oriental de la cúpula lávica parece determinado por la fracturación de la zona superior de la masa lávica en enfriamiento en la chimenea volcánica más bien profunda.La fracturación, evidenciada por la crisis sísmica local de julio de 1980, determinó la exoluci6n desde abajo de fases gaseosas con elevada temperatura. Reacciones superficiales de oxidación contribuyeron al aumento de la temperatura de los gases.Las investigaciones geomagnéticas confirmaron que el aumento de temperatura afectó una zona restringida y superficial alrededor de la cúpula lávica. Esta interpretación hace excluir que el aumento de temperatura (de 92ºC hasta 960ºC) pudo ser determinado por la subida de masas magmáticas.