bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation
Authors: Nazzari Sarah , Fearon Pasco , Rice Frances , Molteni Massimo , Frigerio Alessandra 
Published: November 2021

BackgroundEmerging evidence suggests that antenatal exposure to maternal stress signals affects the development of the infant stress response systems. Animal studies indicate that maternal sensitive caregiving can reverse some of these effects. However, the generalizability of these findings to humans is unknown. This study investigated the role of maternal caregiving in the association between multiple markers of maternal antenatal stress and infant stress regulation.MethodsThe sample consisted of 94 mother‐infant (N = 47 males, mean postnatal weeks = 12; SD = 1.84) dyads. Maternal levels of Interleukin‐6, C‐Reactive Protein (CRP), diurnal cortisol and alpha amylase, depressive and anxiety symptoms were assessed in late pregnancy (mean gestational age = 34.76; SD = 1.12), whereas postnatal symptomatology, caregiving, and infant cortisol response to the inoculation were evaluated at 3 months.ResultsHierarchical linear models (HLMs) showed a significant interaction between maternal antenatal cortisol, caregiving, and time on infant cortisol reactivity, while controlling for gender, maternal age, and postnatal depression. Specifically, higher levels of maternal antenatal cortisol were associated with greater cortisol response only among infants of less emotionally available mothers. All other markers of antenatal stress were not significantly associated with infant cortisol reactivity either independently or in interaction with maternal caregiving.ConclusionsAlbeit preliminary, results provide the first evidence in humans that maternal sensitive caregiving may eliminate the association between antenatal maternal cortisol and infant cortisol regulation.
The influence of thermal cues on the reproductive phenology ofSilverShiner,Notropis photogenis
Authors: Burbank Jacob , Drake D. Andrew R. , Power Michael 
Published: November 2021

AbstractReproductive phenology and the length of the growing season vary in response to interannual environmental variability, with implications for population dynamics of freshwater fishes. Understanding the reproductive phenology of imperilled species in relation to environmental conditions is needed to better evaluate potential responses to changing environmental conditions, estimate future population dynamics and develop comprehensive recovery strategies. We examined Silver Shiner, a species listed as “Threatened” under Canada'sSpecies at Risk Act, during spring 2018 and 2019 to better understand the reproductive phenology of the species at the northern edge of its range in Canada. The initiation of Silver Shiner spawning occurred on the descending limb of the hydrograph and was completed before the onset of the extended period of low summer flow. In addition, both the initiation and cessation of spawning occurred in response to a cumulative growing degree day base 5 (GDD5) cue, with logistic regression models indicating a 50% probability the population initiated and ceased spawning when GDD5reached 68°C•days and 368°C•days, respectively. Logistic regression incorporating GDD5effectively predicted spawning initiation and cessation, providing useful models for examining the impacts of alterations to the thermal regime on reproductive phenology and improving the ability to evaluate changes in the larval growth period. Furthermore, the models can facilitate the development of real‐time estimates of spawning activity, and therefore ensure that disturbance to the species is minimized during the sensitive reproductive period.
Fast 3D imaging of giant unilamellar vesicles using reflected light‐sheet microscopy with single molecule sensitivity
Authors: Jannasch Anita , Szilagyi Sven A. , Burmeister Moritz , Davis Q. Tyrell , Hermsdorf Gero L. , De Suman , Schäffer Erik 
Published: November 2021

SummaryObservation of highly dynamic processes inside living cells at the single molecule level is key for a better understanding of biological systems. However, imaging of single molecules in living cells is usually limited by the spatial and temporal resolution, photobleaching and the signal‐to‐background ratio. To overcome these limitations, light‐sheet microscopes with thin selective plane illumination, for example, in a reflected geometry with a high numerical aperture imaging objective, have been developed. Here, we developed a reflected light‐sheet microscope with active optics for fast, high contrast, two‐colour acquisition of ‐stacks. We demonstrate fast volume scanning by imaging a two‐colour giant unilamellar vesicle (GUV) hemisphere. In addition, the high contrast enabled the imaging and tracking of single lipids in the GUV cap. The enhanced reflected scanning light‐sheet microscope enables fast 3D scanning of artificial membrane systems and potentially live cells with single‐molecule sensitivity and thereby could provide quantitative and molecular insight into the operation of cells.
Chinese late‐life immigrants’ loneliness and social isolation in host countries: An integrative review
Authors: Zhao Ivy Yan , Holroyd Eleanor , Garrett Nick , Wright‐St Clair Valerie A. , Neville Stephen 
Published: November 2021

AbstractAims and objectiveTo synthesise current international empirical evidence on loneliness and social isolation in Chinese late‐life immigrants.BackgroundLoneliness causes adverse health consequences in Chinese late‐life immigrants leading to increased utilisation of often increasingly limited healthcare resources. However, little is known about how Chinese late‐life immigrants perceive and experience loneliness and social isolation in their host countries.DesignAn integrative review methodology.MethodsUsing a systematic search strategy, Google scholar and databases, such as Scopus, Web of Science, PubMed, CHNAHL, Medline and open access Theses were searched. No limitation was placed on publication date. Peer‐reviewed studies published from the database inception to May 6, 2021 in the English language were included. The review process is reported according to PRISMA.ResultsEight articles met the criteria and were included in this review. Two themes resulting from the data synthesis process were identified. Firstly, ‘disrupted social relations after late‐life immigration’ and secondly ‘moving away from filial expectations’.ConclusionLoneliness and social isolation are commonly experienced by Chinese late‐life immigrants when residing in host countries. Understanding and identification of the sources of loneliness and social isolation among late‐life immigrants are essential prompts for healthcare professionals, particularly nurses, to engage sensitively with Chinese late‐life immigrants. Nurses culturally relevant care delivery in a variety of settings may best serve recipients’ social and health related needs.Relevance to clinical practiceThis integrated review informs the planning of health and social services for addressing Chinese late‐life immigrants’ experiences of loneliness and social isolation. Focused attention on cultural responsiveness is an important component of providing quality and safe nursing care. This review of the recent evidence on socially‐rooted health concerns affected by both immigration and ageing will help advance nursing practice in providing culturally responsive care interventions.
Inside the technology showroom: Sequence of technology demonstrations and willingness to collaborate
Authors: Gillier Thomas , Schweitzer Fiona 
Published: November 2021

AbstractTo support their open innovation strategy, many research technology organizations (RTOs) demonstrate their mature and emerging technologies in showrooms. However, little is known about how RTOs should showcase their technologies to attract new R&D partners. Drawing on construal level theory, we propose that the right order of technology demonstrations depends on the visitors’ level of technical expertise. An empirical field experiment of 139 showroom visitors at the CEA Tech showroom, a world‐leading French technology showroom for micro‐technologies supports our theorizing. Visitors with little technical expertise are most willing to collaborate when they feel creatively inspired. This is likely to happen when visitors see emerging technologies before mature ones because it elicits a high construal level. In contrast, visitors with high technical expertise are more willing to collaborate when they perceive complementary resources. This is likely to occur when the demonstrations alternate between emerging and mature technologies because it elicits construal level shifts. We discuss the study's theoretical and practical implications for outbound open innovation and construal level theory.
A comprehensive review of invasion and ecological impacts of introduced common carp (Cyprinus carpio) in Lake Naivasha, Kenya
Authors: Mutethya Eunice , Yongo Edwine 
Published: November 2021

AbstractInvasive fish species pose considerable threats to aquatic biodiversity. The fishery of Lake Naivasha was enhanced by introduction of invasive fish species, including carp. The present study examined factors driving successful carp invasions, and their ecological impacts, knowledge of both being essential for management purposes. The present study revealed that carp invaded the lake, probably due to its adaptive traits such as environmental tolerance, fast growth, high fecundity, early sexual maturation and food flexibility. It reduced the biomass of Oreochromis leucostictus, Coptodon zillii and Micropterus salmoides which initially contributed to the fishery through competition and habitat degradation. It is noteworthy that the biomass of Oreochromis niloticus in the lake has recently increased and surpassed carp, attributable to a reduction in its predator (M. salmoides) and its biological traits. In terms of ecological effects, carp enhance water turbidity and stimulate algal growth by resuspending sediments and associated nutrients through its foraging activities. Although direct removal has been a useful practice for controlling carp in other places, this approach might be impractical for Lake Naivasha, since carp is the main species sustaining the lake fishery. Instead, implementation of effective management measures, including control of fishing effort, pollution control and protection of surrounding wetlands, would promote recovery and long‐term sustainability of the fishery resources of this lake.
Learners’ Engagement in L2 Computer‐Mediated Interaction: Chat Mode, Interlocutor Familiarity, and Text Quality
Authors: DAO PHUNG , NGUYEN MAI XUAN NHAT CHI , DUONG PHUONG–THAO , TRAN–THANH VU 
Published: November 2021

AbstractThis study investigated the impact of synchronous computer‐mediated communication (SCMC) mode and familiarity with partners on learner engagement in second‐language task‐based interaction, and whether learner engagement is linked to subsequent joint‐written‐text quality. Ninety‐eight Vietnamese learners of English were assigned into (±) familiar groups and performed a picture‐sequencing tasks in 2 SCMC modes (i.e., video and text chat). Scores of 3 types of learner engagement (cognitive, social, and emotional) were compared across the conditions. Results showed that scores of all engagement types in the video chat were significantly higher than in the text chat. Familiar dyads also showed higher engagement than unfamiliar peers during the interaction. Learners reported different reasons for their preferences of video chat over text chat. Language‐related episodes, semantically engaged talk, and mutual help as measures of learner engagement were predictive of the subsequent text quality. The results contribute to the general understanding of the characteristics of video and text chat and their impact on learner engagement and text quality.
Plasma membrane intrinsic protein SlPIP1;7 promotes root growth and enhances drought stress tolerance in transgenic tomato (Solanum lycopersicum) plants
Authors: Fan Shuya , Han Nani , Wu Hong , Jia Jianhua , Guo Jia 
Published: November 2021

AbstractPlasma membrane intrinsic proteins (PIPs) play important roles in mediating water transport and regulating plant growth and development. In this study, the function of SlPIP1;7 in drought stress tolerance was characterized. Overexpression of SlPIP1;7 in tomato increased the primary root length and promoted the lateral root growth, whereas the shoot and root growth of SlPIP1;7‐silenced seedlings were severely retarded. Moreover, SlPIP1;7‐overexpressing plants exhibited obviously increased drought stress tolerance because they showed slight withering symptom, whereas the SlPIP1;7‐silenced plants were more sensitive to drought stress. Furthermore, the SlPIP1;7‐overexpressing plants showed higher root hydraulic conductivity (Lpr) and less cell membrane damage and produced less reactive oxygen species (ROS) accumulation under drought stress compared with wild‐type, whereas these indicators were opposite in SlPIP1;7‐silenced plants. These results suggested that overexpression of SlPIP1;7 gene promoted the root growth and the water absorption, maintained the water balance and increased the antioxidant defence ability of plants under drought stress, thereby imparting the drought stress tolerance. SlPIP1;7 is thus a valuable genetic resource to enhance stress tolerance in tomato plants.
Providing social support for inpatients: Insights from a virtual medical student initiative
Authors: Lee Michelle S. , Cheloff Abraham Z. , Jang Youjin Jenny , Yin Sophia H. , Strauss Adam C. , Kanjee Zahir 
Published: November 2021

AbstractBackgroundAlthough the COVID‐19 pandemic increased social isolation among hospitalised patients given isolation precautions, visitor restrictions and curtailed interactions with healthcare teams, medical students had limited opportunities for involvement in the care of inpatients.ApproachWe designed a humanistic and narrative medicine intervention to engage medical students in combating social isolation in hospitalised patients during the COVID‐19 pandemic at a tertiary care teaching hospital. In our programme, medical students provided virtual social support to hospitalised patients via phone by providing assistance connecting with family members, having informal conversations and check‐ins and writing up patient life narratives.EvaluationFrom April 2020 to March 2021, we received 126 referrals of potentially isolated patients from inpatient medical teams. Fifty patients accepted and received our intervention, including 26 who completed life narratives. Feedback was positive, demonstrating benefit to medical students in learning about humanism and connecting with patients through their life stories. In addition, patients and medical teams felt more supported. We share key operational lessons and resources to facilitate the implementation of this intervention elsewhere.ImplicationsOur intervention allows medical students to meaningfully contribute to the care of inpatients, support beleaguered inpatient teams and learn important lessons about humanism in medicine. This educational and patient care intervention holds promise in other settings, including beyond the COVID‐19 pandemic.
Monoclonal antibody treatment for COVID‐19 in solid organ transplant recipients
Authors: Sarrell Bonnie Ann , Bloch Karen , El Chediak Alissar , Kumm Kayla , Tracy Kaitlyn , Forbes Rachel C. , Langone Anthony , Thomas Lora , Schlendorf Kelly , Trindade Anil J. , Perri Roman , Wright Patty , Concepcion Beatrice P. 
Published: November 2021

AbstractSolid organ transplant (SOT) recipients are at high risk for severe coronavirus disease 2019 (COVID‐19). Studies suggest that early intervention with monoclonal antibody (MAB) treatment directed against the SARS‐CoV‐2 spike protein may reduce the risk of emergency department visits or hospitalization for COVID‐19, especially in high‐risk patients. Herein, we describe our single‐center experience of 93 SOT (50 kidney, 17 liver, 11 lung, nine heart, and six dual‐organ) recipients with mild to moderate COVID‐19 who were treated with bamlanivimab or casirivimab‐imdevimab per emergency use authorization guidelines. Median age of recipients was 55 [(Interquartile range) 44–63] years, and 41% were diabetic. Median time from transplant to MAB was 64 (IQR 24–122) months and median time from the onset of COVID‐19 symptoms to the infusion was 6 (IQR 4–7) days. All patients had a minimum 30 days of study follow‐up. The 30‐day hospitalization rate for COVID‐19‐directed therapy was 8.7%. Infusion‐related adverse events were rare and generally mild. Biopsy‐proven organ rejection occurred in two patients, and there were no graft losses or deaths. A comparator group of 72 SOT recipients diagnosed with COVID‐19 who were eligible but did not receive MAB treatment had a higher 30‐day hospitalization rate for COVID‐19‐directed therapy (15.3%), although this difference was not statistically significant, after adjustment for age (Odds Ratio 0.49 [95% Confidence Interval 0.18–1.32],p= 0.16). Our experience suggests that MAB treatment, with respect to the available MAB formulations and circulating viral variants present during our study period, may provide favorable outcomes for mild to moderate COVID‐19 in SOT recipients.
Non fi daffa métti
Authors: Powis Dick 
Published: November 2021

AbstractIn Dakar, Senegal, skilled tradesmen must navigate boom‐and‐bust cycles of the economy—tempos disproportionately influenced by the Islamic calendar, foreign investment, and an individual’s access to social capital. Anticipating these cycles, drawing on community networks for support, and learning to weather the bad times can mean the difference between providing for your family and having your masculinity questioned. Both Dakar and its builders are always under construction, ever in progress.
Application of locking compression plates as type 1 external fixators to treat unilateral mandibular fractures in four equids and one dromedary
Authors: Mählmann Kathrin , Noguera Cender Andrea , Ehrle Anna , Lischer Christophorus J. 
Published: November 2021

AbstractObjectivesTo describe a novel fixation of open, unstable, unilateral mandibular fractures applying a locking compression plate as an external skeletal fixator (ESF‐LCP).AnimalsFour horses and one dromedary.Study designShort case series.MethodsAnimals presented with unstable, open, unilateral fractures of the mandible. Fracture fixation was performed under general anesthesia. A 4.5/5.5 narrow LCP was applied externally above the level of the skin and combined with intraoral tension band wiring.ResultsFracture fixation was achieved successfully using an ESF‐LCP. Minimal tissue manipulation was required during application and removal of the construct. The ESF‐LCPs provided adequate access to the wounds at the fracture site, were well tolerated, and did not interfere with any objects in the animals’ environment. Mild drainage at the screw‐skin interface developed in all cases, requiring early implant removal due to surgical site infection in one case. The use of longer plates was associated with superficial pressure necrosis of the skin in the masseter area in two cases. Implants were removed after 3 to 12 weeks, and the long‐term functional outcome after 11 to 41 (median 13) months was good in all cases.ConclusionStabilization of mandibular fractures with ESF‐LCP led to good outcomes in this case series. The use of longer plates positioned more caudally and in a ventrolateral position seemed associated with surgical site infection and pressure necrosis of the skin.Clinical significanceUse of a locking compression plate as an external skeletal fixator seems to offer a viable alternative to treat unilateral mandibular fractures, especially when these are open and/or infected.
On Solutions of Fractional Telegraph Model With Mittag–Leffler Kernel
Authors: Akgül Ali , Modanli Mahmut 
Published: November 2021

Abstract
In this paper, we research the fractional telegraph equation with the Atangana–Baleanu–Caputo derivative. We use the Laplace method to find the exact solution of the problems. We construct the difference schemes for the implicit finite method. We prove the stability of difference schemes for the problems by the matrix method. We demonstrate the accuracy of the method by some numerical experiments.
Digital Twin Based Interactive Mechatronics Lab Development for Remote Lab Offering and Evaluation
Authors: Viola Jairo , Guc Furkan , Chen YangQuan , Calderon Mauricio 
Published: November 2021

Abstract
Mechatronics and control education is supported by laboratory intensive assignments that allow students acquire software and hardware skills to solve real world problems. However, COVID-19 force many schools to switch into remote learning complicating the instruction of practical assignments. This paper presents a novel proposal for interactive remote teaching of the laboratory component of the course ME-142: Mechatronics at the University of California, Merced using Digital Twins (DT) and the flipped classroom methodology. Each lab experience is composed by a set of on-demand supporting materials with the foundations of mechatronics simulation using MATLAB/Simulink to enhance and adapt the learning experience of the students. Once the students acquire advanced simulation skills, a set of Digital Twin models are provided to the students in order to begin their interaction with virtual representations of real systems for identification, analysis, controller design and validation, which are available online for remote access. By the end of the course, students were able not only to gain valuable experience with mechatronic systems but also interact and build advanced modelling techniques as Digital Twin, contributing to compensate the lack of remote hardware interaction.
Multiscale Topology Optimization With Gaussian Process Regression Models
Authors: Najmon Joel C. , Valladares Homero , Tovar Andres 
Published: November 2021

Abstract
Multiscale topology optimization (MSTO) is a numerical design approach to optimally distribute material within coupled design domains at multiple length scales. Due to the substantial computational cost of performing topology optimization at multiple scales, MSTO methods often feature subroutines such as homogenization of parameterized unit cells and inverse homogenization of periodic microstructures. Parameterized unit cells are of great practical use, but limit the design to a pre-selected cell shape. On the other hand, inverse homogenization provide a physical representation of an optimal periodic microstructure at every discrete location, but do not necessarily embody a manufacturable structure. To address these limitations, this paper introduces a Gaussian process regression model-assisted MSTO method that features the optimal distribution of material at the macroscale and topology optimization of a manufacturable microscale structure. In the proposed approach, a macroscale optimization problem is solved using a gradient-based optimizer The design variables are defined as the homogenized stiffness tensors of the microscale topologies. As such, analytical sensitivity is not possible so the sensitivity coefficients are approximated using finite differences after each microscale topology is optimized. The computational cost of optimizing each microstructure is dramatically reduced by using Gaussian process regression models to approximate the homogenized stiffness tensor. The capability of the proposed MSTO method is demonstrated with two three-dimensional numerical examples. The correlation of the Gaussian process regression models are presented along with the final multiscale topologies for the two examples: a cantilever beam and a 3-point bending beam.