bluuebunny/crossref_metadata_2025_split huggingface dataset:
How Does Gender Influence Oral Health and Quality of Life?
Authors: Skoskiewicz-Malinowska Katarzyna , Kaczmarek Urszula , Malicka Barbara 
Published: April 2021

Abstract
Background In recent years, there has been an increase in the number of ageing people and women have a longer life expectancy compared to men. This study aims to compare oral health parameters and conduct a psychometric assessment using standardised questionnaires in a group of the elderly of both gender aged 65 and more.MethodsThe survey involved 500 residents of Wroclaw, aged 65 and older, of both gender. There was an oral and questionnaire examination performed. QoL was evaluated using Euro-Quality of Life, Oral Health Impact Profile-14 and Patient Health Questionnaire, which were validated for the Polish population. The relationship strength between psychometric scale scores and sociodemographic and clinical factors was determined by calculating Spearman's linear correlation coefficient values and regression coefficient values.ResultsThe prevalence of xerostomia assesed by the Challacombe scale was diagnosed significantly more frequently in women then men. (36.9% vs. 25.5%; p = 0.076). The men were significantly more likely to have high treatment needs (36.1% vs. 26.9%; p = 0.032) and they required urgent dental treatment (7.2% vs. 2.8%; p = 0.022). There were no statistically significant differences in terms of QoL evaluated by EQ-5D, EQ-5D VAS or OHIP-14 questionnaires in both subgroups (6.7±1.9 vs. 7.1±2.2, 66.1±18.6 vs. 67.9±20.9, 8.5±14.0 vs. 7.2±12.9; p > 0.05). Only women had higher severity of depressive symptoms measured using the PHQ-9 questionnaire (4.0±4.1 vs. 2.8±3.8; p<0.001).ConclusionIt can be concluded that the independent predictors which significantly affect the high QoL scores on the EQ-5D scale were found to be female gender, age below 75, high or middle income, independence in daily life, a low number of comorbidities, lack of oral treatment needs.
Deep learning of dynamic sea-level variability to investigate the relationship with the floods in Gothenburg
Authors: Sorkhabi Omid Memarian 
Published: April 2021

Abstract
It is important to study the relationship between floods and sea-level rise due to climate change. In this research, dynamic sea-level variability with deep learning has been investigated. In this research sea surface temperature (SST) from MODIS, wind speed, precipitation and sea-level rise from satellite altimetry investigated for dynamic sea-level variability. An annual increase of 0.1 ° C SST is observed around the Gutenberg coast. Also in the middle of the North Sea, an annual increase of about 0.2 ° C is evident. The annual sea surface height (SSH) trend is 3 mm on the Gothenburg coast. We have a strong positive spatial correlation of SST and SSH near the Gothenburg coast. In the next step dynamic sea-level variability is predicted with long short time memory. Root mean square error of wind speed, precipitation, and mean sea-level forecasts are 0.84 m/s, 48 mm and 2.4 mm. The annual trends resulting from 5-year periods, show a significant increase from 28 mm to 46 mm per year in the last 5 year periods. The rate of increase has doubled. The wavelet can be useful for detecting dynamic sea-level variability.
First report of Peronospora variabilis causing downy mildew disease in cañahua (Chenopodium pallidicaule) in Bolivia
Authors: Rollano-Peñaloza Oscar Miguel , Palma-Encinas Valeria D. , Nogales-Ascarrunz Paola M. , Widell Susanne , Rasmusson Allan G. , Mollinedo Patricia A. 
Published: April 2021

Abstract
Cañahua (Chenopodium pallidicaule Aellen) is a semi-domesticated grain cultivated in the Andean highlands for millennia. Cañahua seeds have high nutritional value and it has become attractive because of its high resistance to frost, drought and saline soils. In May 2018, cañahua plants showed symptoms of the downy mildew disease caused by Peronospora variabilis which is known to heavily affect its tetraploid-relative quinoa. Besides the typical symptoms in the plant, visual confirmation of P. variabilis reproductive structures by microscopy was achieved. In order to verify the ability of P. variabilis to infect cañahua, an artificial infection in three cañahua varieties was performed. The three cañahua varieties were infected by P. variabilis and developed downy mildew disease symptoms. The pathogen identity was confirmed by PCR and Sanger sequencing of the PvCox2 and PvITS region. DNA sequence identification confirmed that the P. variabilis that usually infects quinoa can also infect cañahua plants. Therefore, cañahua when grown next to quinoa must be carefully watched for downy mildew disease symptoms because P. variabilis can be a potential threat for future large scale cañahua agriculture.
Assessing Public Interest Based on Wikipedia’s Most Visited Medical Articles During the SARS-CoV-2 Outbreak: Search Trends Analysis
Authors: Chrzanowski Jędrzej , Sołek Julia , Fendler Wojciech , Jemielniak Dariusz 
Published: April 2021

Background
In the current era of widespread access to the internet, we can monitor public interest in a topic via information-targeted web browsing. We sought to provide direct proof of the global population’s altered use of Wikipedia medical knowledge resulting from the new COVID-19 pandemic and related global restrictions.

Objective
We aimed to identify temporal search trends and quantify changes in access to Wikipedia Medicine Project articles that were related to the COVID-19 pandemic.

Methods
We performed a retrospective analysis of medical articles across nine language versions of Wikipedia and country-specific statistics for registered COVID-19 deaths. The observed patterns were compared to a forecast model of Wikipedia use, which was trained on data from 2015 to 2019. The model comprehensively analyzed specific articles and similarities between access count data from before (ie, several years prior) and during the COVID-19 pandemic. Wikipedia articles that were linked to those directly associated with the pandemic were evaluated in terms of degrees of separation and analyzed to identify similarities in access counts. We assessed the correlation between article access counts and the number of diagnosed COVID-19 cases and deaths to identify factors that drove interest in these articles and shifts in public interest during the subsequent phases of the pandemic.

Results
We observed a significant (P<.001) increase in the number of entries on Wikipedia medical articles during the pandemic period. The increased interest in COVID-19–related articles temporally correlated with the number of global COVID-19 deaths and consistently correlated with the number of region-specific COVID-19 deaths. Articles with low degrees of separation were significantly similar (P<.001) in terms of access patterns that were indicative of information-seeking patterns.

Conclusions
The analysis of Wikipedia medical article popularity could be a viable method for epidemiologic surveillance, as it provides important information about the reasons behind public attention and factors that sustain public interest in the long term. Moreover, Wikipedia users can potentially be directed to credible and valuable information sources that are linked with the most prominent articles.
Distributed Ledger Infrastructure to Verify Adverse Event Reporting (DeLIVER): Proposal for a Proof-of-Concept Study
Authors: Milne-Ives Madison , Lam Ching , Rehman Najib , Sharif Raja , Meinert Edward 
Published: April 2021

Background
Adverse drug event reporting is critical for ensuring patient safety; however, numbers of reports have been declining. There is a need for a more user-friendly reporting system and for a means of verifying reports that have been filed.

Objective
This project has 2 main objectives: (1) to identify the perceived benefits and barriers in the current reporting of adverse events by patients and health care providers and (2) to develop a distributed ledger infrastructure and user interface to collect and collate adverse event reports to create a comprehensive and interoperable database.

Methods
A review of the literature will be conducted to identify the strengths and limitations of the current UK adverse event reporting system (the Yellow Card System). If insufficient information is found in this review, a survey will be created to collect data from system users. The results of these investigations will be incorporated into the development of a mobile and web app for adverse event reporting. A digital infrastructure will be built using distributed ledger technology to provide a means of linking reports with existing pharmaceutical tracking systems.

Results
The key outputs of this project will be the development of a digital infrastructure, including a backend distributed ledger system and an app-based user interface.

Conclusions
This infrastructure is expected to improve the accuracy and efficiency of adverse event reporting systems by enabling the monitoring of specific medicines or medical devices over their life course while protecting patients’ personal health data.

International Registered Report Identifier (IRRID)
PRR1-10.2196/28616
Case analysis of energy consumption of the existing office building in the severe cold region
Authors: Chuan Ma , Jiajia Liu , Guangfu Cui , Manglink R.N. 
Published: April 2021

Abstract
With the relevant requirements of energy-saving and green buildings put forward by our country, carrying out the building energy consumption analysis is the premise and foundation of implementing energy-saving improvement of the existing buildings. Nowadays, modern office buildings, whose energy consumption structure and proportion are relatively stable, are widely used. The energy review work of an existing office building in severe cold region is carried out. Investigation and statistics on the general situation of buildings, the general situation of energy consumption and water system consumption and the total energy consumption are implemented. Based on the audit, the energy consumption situation and characteristics in a certain year are analysed. According to the characteristics of energy-using structure, the energy-saving potential of buildings is analysed, and the reasonable energy-saving opinions and suggestions are proposed to provide theoretical support for the energy-saving management of office buildings in severe cold areas.
Stochastic orders for a multivariate Pareto distribution
Authors: Catana Luigi-Ionut 
Published: April 2021

Abstract
In this article we give some theoretical results for equivalence between different stochastic orders of some kind multivariate Pareto distribution family. Weak multivariate orders are equivalent or imply different stochastic orders between extremal statistics order of two random variables sequences. The random variables in this article are not neccesary independent.
Algorithms for Railway Embedded Control Devices for Safety Manoeuvres
Authors: Beinaroviča Anna , Gorobetz Mikhail , Alps Ivars 
Published: April 2021

Abstract
This study is dedicated to solve manoeuvres making task while working on the station with no marshalling hump. It is part of the project aimed at the development of intelligent safety and optimal control systems of autonomous electric vehicles and transport in general. The main manoeuvres safety depends on the lack of items and other objects on the rails as well as on the position of turnouts. In most cases rails, occupied with other wagons, as well as the wrong position of turnouts are marked with prohibiting red or blue signals of the traffic light. The authors propose an algorithm for the traffic light recognition by using a convolutional neural network (CNN) and traffic light indicator recognition. However, the situation when the locomotive needs to drive on the rails occupied with other wagons, for example, during the manoeuvres on the railway station can also appear. For this purpose, the authors have developed a CNN algorithm for the wagon recognition on the rails.
Correlation of the Local Projection System with the National System
Authors: Filip Larisa Ofelia , Cucăilă Simona 
Published: April 2021

Abstract
In areas with border extension (localities, mining areas, hydrotechnics, etc.) it is advisable to establish the positions of the points in a local system, the methods used being simpler and the results more precise. However, it is necessary to transcalculate the coordinates from the local system to the national projection system. A transcalculation method is assumed to ensure efficiency and accuracy.
17. Within-Object Attention: Attentional Concentration and Amplification in Moving Versus Static Conditions
Authors: Segal Shira 
Published: April 2021

When presented with multiple stimuli, attention serves to help us select which items to focus on for further processing. The techniques we apply to determine where to focus within an object are less clearly understood than those applied for selecting objects. This study aims to observe if there are any existing trends in how we allocate our attention within objects, as well as to examine how different factors affect this cognitive process. Two previously identified trends in how attention is allocated within lines are attentional concentration – a tendency to focus on the center of the lines – and attentional amplification – the increase in center focus as line length increases (Alvarez and Scholl, 2005). Object dynamics is a variable that can be manipulated to test if these effects represent a higher-order tracking strategy, or whether they will still be exhibited when presented with stationary lines. This study examines whether these effects can be replicated when tested with moving lines as well as stationary lines. 22 participants completed tracking tasks, either moving or static, where they tracked two designated target lines while simultaneously watching for the appearance of a probe at either the center or end of any of the lines. In the moving condition, probe detection was significantly lower at the ends of lines (indicating attentional concentration), and this decrease in performance grew slightly as line length increased (indicating weak attentional amplification); however, no significant differences in probe detection between centers and ends of lines were found in the static condition.
Commentary on Post, et al. Ultra-early tranexamic acid after subarachnoid hemorrhage: A randomized controlled trial. Lancet 2021
Authors: Lo Benjamin W. Y. , Fukuda Hitoshi , Tsang Anderson C. O. , Langer David J. , Miyawaki Satoru , Koyanagi Masaomi , Lui Matthew Wai-Man 
Published: April 2021

Background:
Tranexamic acid (TA) administration in aneurysmal subarachnoid hemorrhage (SAH) within the first 24 hours may reduce the incidence of early aneurysmal rebleeding. However, this is also the potential for an increased risk of delayed cerebral ischemia if TA is administered for more than 72 hours following the initial aneurysmal rupture.

Methods:
In the ultra-early tranexamic acid after subarachnoid hemorrhage randomized controlled trial by Post et al., patients were randomized to receive TA within the first 24 hours, or until start of aneurysm treatment. These results were compared to a matched control group.

Results:
Ultra-early administration (≤24 h) of TA reduced the incidence of rebleeding, and did not alter the incidence of delayed cerebral ischemia and/or extracranial thrombosis. Further, no significant differences were noted between the TA group and control arm in the incidence of good (modified Rankin scores 0-3) clinical outcomes at 6 months.

Conclusion:
Ultra-early administration of TA (≤24 h) resulted in a lower rate of recurrent hemorrhage, without increasing the incidence of delayed cerebral ischemia in SAH patients.
Specificity of the effect of double fractures of the rhythmogram on the daily variability of the sinus rhythm in patients with pulmonary and arterial hypertension
Authors: Sobolev Alexander V. , Ryabykina Galina V. , Kozhemyakina Elena Sh. 
Published: April 2021

Introduction. In contrast to coronary heart disease (CHD), heart failure and a number of other diseases, in arterial and pulmonary hypertension, the deterioration of the functional state of the patient is often not accompanied by a decrease in the parameters of his sinus rhythm variability (SRV) for long periods of time. Moreover, an increase in age and an increase in blood pressure in patients with hypertension may lead not to a decrease, but to an increase in the parameters of daily SRV. It is noted that with hypertension on the sinus rhythm, the number of so-called double fractures of the rhythmogram (DFR) sequences of RR intervals short-long-short-long becomes greater, which can greatly affect the daily SRV.
Aim. To study the specifics of the effect of DFR on daily SRV in arterial and pulmonary hypertension.
Materials and methods. 300 Holter ECG records were analyzed, including 67 records of healthy persons, 20 records of CHD patients with CAG-confirmed vascular damage, 126 records of patients with arterial hypertension and 87 records of patients with idiopathic pulmonary hypertension. In the analysis of daily SRV, a modification of the SRV analysis method developed at the National Medical Research Center of Cardiology, taking into account the presence of DFR, was used.
Results. It is shown that DFR reflects the processes of regulation of the sinus rhythm, which are affected differently by CHD and hypertension. In CHD, the frequency of DFR and its effect on the daily SRV significantly decreases (compared to the norm). With hypertension, the frequency of the appearance of DFR increases; there is a clear trend towards a decrease in SRV in comparison with the norm in the areas without DFR; in areas with DFR, this trend is less pronounced or absent, and at ages over 50 years, SRV increases.
Conclusion. When studying the daily SRV of patients with arterial and idiopathic pulmonary hypertension, it is necessary to take into account the effect of DFR on the increase in SRV.
Identifying Priorities for Marine Tourism Development at Tanggamus Regency, Lampung
Authors: Annishia Fristi Bellia 
Published: April 2021

This research aims to determine priorities for the development of marine tourism in Tanggamus Regency. To obtain recommendation for priority for marine tourism development, this research focuses on three marine tourism destinations that managed by Tourism Awareness Group (Pokdarwis) together with Tanggamus Government, namely Kiluan Bay, Karang Putih Beach, and Muara Indah Tourism Park. Focus Group Discussions (FGD) as well as questionnaire were conducted with informants from Tourism, Culture, Youth and Sports Agency of Tanggamus Regency, and Pokdarwis representatives from management of the research location. This research uses Analytical Hierarchy Process (AHP) method, and the priority preferences for the development of marine tourism are assessed from the aspects of connectivity (C1), governments program support (C2), potential problems (C3), and potential value-added locations (C4). The results show indicators in each data cluster prioritize Kiluan Bay as the first priority to be developed. The results also recommend to increase tourism promotions in the airport area and optimizing the constructions of access roads (C1), synchronizing tourism development plans in the Regional Spatial Plan to the Lampung Province Medium-Long Term Development Plan and facilitating investors in the tourism sectors (C2), educating the public regarded the potential dangers of disasters (C3), supporting for accommodations, local communities attractions and culinary centers (C4).
Keywords: Analytical Hierarchy Process, Marine Tourism, Priorities of Development.
Política monetária e a (não) neutralidade da moeda
Authors: Santana Bernardo , Arantes Elaine 
Published: April 2021

O objetivo deste artigo é esclarecer a relação entre as diferentes visões das escolas Austríaca, Pós-Keynesiana, Novo-Clássica e Novo-Keynesiana sobre o impacto da moeda na economia e as recomendações de políticas monetárias. O arcabouço teórico aborda estas quatro escolas e permite compreender suas percepções a respeito da neutralidade ou não neutralidade da moeda. As diferenças nas percepções estão ligadas às recomendações ou rejeições de interferências governamentais por meio de políticas monetárias. Apresentam-se estas percepções, comparando os efeitos da expansão monetária no longo prazo de acordo com cada escola. Discute-se a atuação do Banco Central como agente estimulador da economia de acordo com cada escola. Tratar a moeda como neutra ou não neutra não significa ter a mesma visão a respeito dos impactos que ela causa no sistema econômico. Cada escola tem suas hipóteses e um entendimento específico e diferenciado quanto às consequências da manipulação da moeda através de intervenções governamentais via políticas monetárias acomodatícias. Uma visão clara sobre a moeda e seu papel é fundamental para se evitar políticas governamentais equivocadas que em certos momentos podem agravar ou criar mais problemas do que soluções. Trata-se de uma pesquisa qualitativa com alcance explicativo fundamentada em levantamento bibliográfico.
COMPARISON BETWEEN SERUM CREATININE AND SERUM CYSTATIN C LEVEL IN DIAGNOSING EARLY DIABETIC NEPHROPATHY IN NEWLY DIAGNOSED TYPE 2 DIABETES MELLITUS
Authors: Prasad Janmeshwar , Singh Manish Kumar , Anwer Md. Rashid , . Shyama 
Published: April 2021

Background: This study was done to evaluate clinical usefulness of cystatin C levels of serum and urine in predicting renal impairment in normoalbuminuric patients with type 2 diabetes and to evaluate the association between albuminuria and serum/urine cystatin C. Cockroft-Gault equation was previously used for GFR calculation. The most recently advocated formula for calculating the GFR are The modification of diet in renal disease study group ,CKD-EPI equation(2009),CKD-EPI cystatin C(2012), CKD-EPI creatinine –cystatin C(2012). The cystatin C levels of serum and urine could be useful markers for renal dysfunction in type 2 diabetic patients with normoalbuminuria.
Conclusion; This finding has major implications for clinical research and early intervention to prevent development of chronic kidney disease in patients with type 2 Diabetes mellitus.
Keywords: Cystatin C, Diabetic Nephropathies, Albuminuria
PHYTOCHEMICAL SCREENING AND ANTIACNE ACTIVITY OF LEAVES EXTRACT OF LAGERSTROEMIA INDICA
Authors: Vishwakarma Vandana , Patel Narendra , Budholiya Prabhakar 
Published: April 2021

Medicinal plants have bioactive compounds which are used for curing of various human diseases and also play an important role in healing. Secondary constituents contain alkaloids, flavonoids, phenol, sapon in, steroids and tannins. Medicinal plants have anticancer, antimicrobial, antidiabetic, antidiuretic and anti-inflammation activities. The increasing interest in powerful biological activity of secondary metabolites outlined the necessity of determining their contents in medicinal plants. In Indian Ayurvedic system, Lagerstroemia Indica (Lythraceae) are well-known plants used for major and minor ailments. The aim of the present study is to examine leaf of Lagerstroemia Indica for phytochemical profile, antioxidant potential, antimicrobial including anti acne activity. Qualitative analysis of various phytochemical constituents and quantitative analysis of total phenolics and flavonoids were determined by the well-known test protocol available in the literature. Quantitative analysis of phenolic and flavonoids was carried out by FolinsCiocalteau reagent method and aluminium chloride method respectively. Phytochemical analysis revealed the presence of phenols, flavonoids, tannins, saponins, alkaloids, fixed oil and fats. The present study concluded that the crude extract of Lagerstroemia Indica is a rich source of secondary phytoconstituents which impart significant antioxidant potential. The extract of Lagerstroemia Indica possess antimicrobial effectiveness againt P. acne and other microbes, In Vitro anti acne activity. The findings of the present study will be helpful to phytochemists, pharmacologists and pharmaceutical industries.
Keywords: Lagerstroemia Indica, Phytochemical, Antioxidant, Antiacne.