bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proposals for person‐centred care in the COVID‐19 era. Delphi study
Authors: Mira José J. , Blanco Martín , Cheikh‐Moussa Kamila , Solas Olga , Alonso Aquilino , Gutierrez Rodrigo , Gómez Celia , Guilabert Mercedes 
Published: February 2021

AbstractBackgroundIn this COVID‐19 era, we need to rethink the criteria used to measure the results of person‐centred care strategies.ObjectiveTo identify priorities, and criteria that health services can use to pursue actually the goal of achieving person‐centred care.DesignThree‐phase online qualitative study performed during May–July of 2020 using the Delphi technique.Setting and ParticipantsAn online platform was used for a consensus meeting of 114 participants, including health planning experts, health‐care institution managers, clinicians and patients.Main Outcome MeasuresCriteria and indicators for the achievement of person‐centred care.Main ResultsThe first round began with 125 proposals and 11 dimensions. After the second round, 28 ideas reached a high level of consensus among the participants. Ultimately, the workgroup agreed on 20 criteria for goals in the implementation of person‐centred care during the COVID‐19 era and 21 related indicators to measure goal achievement.DiscussionNine dimensions and 28 priorities were identified. These priorities are also in accordance with the quadruple aim approach, which emphasizes the need for care for health‐care professionals, without whom it is impossible to achieve a better quality of care.ConclusionsPerson‐centred care continues to be a key objective. However, new metrics are needed to ensure its continued development during the restoration of public health services beyond the control of COVID‐19.Patient or Public ContributionTwelve professionals and patient representatives participated voluntarily in the construction of the baseline questionnaire and in the selection of the criteria and indicators using an online platform for consensus meetings.
Recognition of an Early Triassic accretionary complex in the Nedamo Belt of the Kitakami Massif, Northeast Japan: New evidence for correlation with Southwest Japan
Authors: Uchino Takayuki 
Published: February 2021

AbstractThe Kitakami Massif of the Tohoku district, Northeast Japan, consists mainly of the South Kitakami Belt (Silurian–Cretaceous forearc shallow‐marine sediments, granitoids, and forearc ophiolite) and the North Kitakami Belt (a Jurassic accretionary complex). The Nedamo Belt (a Carboniferous accretionary complex) occurs as a small unit between those two belts. An accretionary unit in the Nedamo Belt is lithologically divided into the Early Carboniferous Tsunatori Unit and the age‐unknown Takinosawa Unit. In order to constrain the accretionary age of the Takinosawa Unit, detrital zircon U–Pb dating was conducted. The new data revealed that the youngest cluster ages from sandstone and tuffaceous rock are 257–248 Ma and 288–281 Ma, respectively. The Early Triassic depositional age of the sandstone may correspond to a period of intense magmatic activity in the eastern margin of the paleo‐Asian continent. A 30–40 my interval between the youngest cluster ages of the sandstone and the tuffaceous rock can be explained by the absence of syn‐sedimentary zircon in the tuffaceous rock. The new detrital zircon data suggest that the Takinosawa Unit can be distinguished as an Early Triassic accretionary complex distinct from the Early Carboniferous Tsunatori Unit. This recognition establishes a long‐duration northeastward younging polarity of accretionary units, from the Carboniferous to Early Cretaceous, in the northern Kitakami Massif. Lithological features and detrital zircon spectra suggest that the Early Triassic Takinosawa Unit in the Nedamo Belt is comparable with the Hisone and Shingai units in the Kurosegawa Belt in Shikoku. The existence of this Early Triassic accretionary complex strongly supports a pre‐Jurassic geotectonic correlation and similarity between Southwest and Northeast Japan.
Immune response during hantavirus diseases: implications for immunotherapies and vaccine design
Authors: Saavedra Farides , Díaz Fabián E. , Retamal‐Díaz Angello , Covián Camila , González Pablo A. , Kalergis Alexis M. 
Published: February 2021

SummaryOrthohantaviruses, previously named hantaviruses, cause two emerging zoonotic diseases: haemorrhagic fever with renal syndrome (HFRS) in Eurasia and hantavirus cardiopulmonary syndrome (HCPS) in the Americas. Overall, over 200 000 cases are registered every year worldwide, with a fatality rate ranging between 0·1% and 15% for HFRS and between 20% and 40% for HCPS. No specific treatment or vaccines have been approved by the U.S. Food and Drug Administration (FDA) to treat or prevent hantavirus‐caused syndromes. Currently, little is known about the mechanisms at the basis of hantavirus‐induced disease. However, it has been hypothesized that an excessive inflammatory response plays an essential role in the course of the disease. Furthermore, the contributions of the cellular immune response to either viral clearance or pathology have not been fully elucidated. This article discusses recent findings relative to the immune responses elicited to hantaviruses in subjects suffering HFRS or HCPS, highlighting the similarities and differences between these two clinical diseases. Also, we summarize the most recent data about the cellular immune response that could be important for designing new vaccines to prevent this global public health problem.
Factors influencing workplace social capital among registered nurses in China
Authors: Xu J.‐M. , Kunaviktikul W. , Akkadechanunt T. , Nantsupawat A. , Turale S. 
Published: February 2021

AimTo examine the modifiable predictors and the level of workplace social capital, transformational leadership, emotional intelligence and organizational justice among registered nurses in Chinese hospitals.BackgroundWorkplace social capital is a relational network developed among nurses and other healthcare professionals that provides social support, and gives value to their working lives. Internationally, cultivating high levels of social capital is critical as it can help improve nurse satisfaction and care, and address nurse turnover. However, knowledge of factors influencing nurses’ workplace social capital is limited in China.MethodsIn this cross‐sectional, descriptive predictive study, 344 registered nurses were randomly selected from three urban Chinese hospitals in Zhejiang province. Five standard instruments were applied to collect data. Descriptive statistics were used to present the level of the variables and stepwise multiple regression was performed to identify the predictors of nurses’ workplace social capital.ResultsAmong eight potential factors, transformational leadership and emotional intelligence positively predicted workplace social capital. Nurses perceived the overall level of workplace social capital, emotional intelligence and unit managers’ transformational leadership as high, and the overall level of organizational justice as moderate.DiscussionEnhancing unit managers’ transformational leadership and nurses’ emotional intelligence was found to positively influence the development of workplace social capital. Although it is not a predictor of workplace social capital, nurses’ organizational justice should be improved due to its importance and current unsatisfactory level.Conclusion and implications for nursing and health policyNursing and health policymakers need to consider the enhancement of transformational leadership and emotional intelligence when implementing policies to improve nurses’ workplace social capital, nursing retention and job satisfaction.
Surface damage resistance and yielding of chemically strengthened silicate glasses: From normal indentation to scratch loading
Authors: Sani Gohar , Limbach Rene , Dellith Jan , Sökmen İlkay , Wondraczek Lothar 
Published: February 2021

AbstractWe report on surface elasticity, plastic deformation and crack initiation of chemically strengthened soda‐lime silicate and sodium aluminosilicate glasses during lateral indentation and scratch testing. Instrumented indentation using a normal indenter set‐up corroborated previous findings on the effects of chemical strengthening on surface Young's modulus, hardness, and indentation cracking. Using lateral indentation in the elastic‐plastic regime, we find a pronounced increase in the scratch hardness as a result of chemical strengthening, manifest in higher work of deformation required for creating the scratch groove. Thereby, the glass composition is found to play a stronger role than the absolute magnitude of surface compressive stress. Using a blunt conical stylus for instrumented scratch testing reveals three distinct modes of scratch‐induced surface fracture, which occur during scratching or after unloading. Occasional micro‐cracking caused by pre‐existing surface flaws at low scratching load can be completely suppressed through chemical strengthening. The intrinsic defect resistance to microcracking is reduced as a result of ion stuffing, depending on the initial glass composition, whereas the resistance to abrasive yielding is enhanced by several hundred MPa.
Unravelling potential northward migration pathways for tree species under climate change
Authors: Boisvert‐Marsh Laura , de Blois Sylvie 
Published: February 2021

AbstractAimClimate‐induced range expansion ultimately implies recruitment at sites that were previously unoccupied by a species (i.e. colonization events). Using evidence on abiotic conditions and biotic interactions at these migration sites, we aimed to identify migration pathways from northern temperate to boreal forests for species showing northward range expansion.LocationQuebec, Canada.TaxonTrees of northern temperate/boreal forests.MethodsUsing past (1970–1977) and recently updated (2003–2015) forest inventories across 761,100 km2, we first quantified latitudinal shifts for saplings of eight tree species and investigated colonization events at migration sites. We used field evidence and a consensus modelling approach to determine environmental suitability and identify edaphic, climatic and disturbance conditions, as well as species co‐occurrence patterns, characterizing recent colonization events. The results were interpreted in relation to novel species associations facilitating species migration in unsuitable landscapes.ResultsAll species showed northward latitudinal shifts driven by increased recruitment and colonization northward. Colonization events occurred largely at historically unsuitable sites. Migration sites showed a shift towards humus types characteristic of the boreal forest and not typically found in the core range of most temperate species. Climatic conditions at migration sites were initially colder than at occupied sites, but warming suggests recent climatic suitability. A decrease in conifer basal area at migration sites following disturbances reduced priority effects that possibly constrained deciduous species establishment. Co‐occurrence patterns pointed to deciduous species tolerant of boreal edaphic conditions, leading the way for other temperate species.Main conclusionsTemperate tree species can recruit into sites typical of boreal forests, even under environmentally challenging conditions. Warming and disturbances open up the way for some novel species associations that in turn have the potential to facilitate the recruitment of temperate species into the boreal forest, revealing migration pathways.
Exosomal miR‐27 negatively regulates ROS production and promotes granulosa cells apoptosis by targeting SPRY2 in OHSS
Authors: Liu Kailu , Yang Weijie , Hu Mengting , Xie WenXiu , Huang Jingyu , Cui Meiting , He Xi , Nie Xiaowei 
Published: February 2021

AbstractOvarian hyperstimulation syndrome (OHSS) is one of the most dangerous iatrogenic complications in controlled ovarian hyperstimulation (COH). The exact molecular mechanism that induces OHSS remains unclear. In recent years, accumulating evidence found that exosomal miRNAs participate in many diseases of reproductive system. However, the specific role of miRNAs, particularly the follicular fluid‐derived exosomal miRNAs in OHSS remains controversial. To identify differentially expressed follicular fluid exosomal miRNAs from OHSS and non‐OHSS patients, the analysis based on miRNA‐sequence was conducted. The levels of 291 miRNAs were significantly differed in exosomes from OHSS patients compared with normal control, and exosomal miR‐27 was one of the most significantly down‐regulated miRNAs in the OHSS group. By using MiR‐27 mimic, we found it could increase ROS stress and apoptosis by down‐regulating the expression of p‐ERK/Nrf2 pathway by negatively regulating SPRY2. These data demonstrate that exosomal miRNAs are differentially expressed in follicular fluid between patients with and without OHSS, and follicular fluid exosomal miR‐27 may involve in the pathological process of OHSS development.
Does maternal psychopathology bias reports of offspring symptoms? A study using moderated non‐linear factor analysis
Authors: Olino Thomas M. , Michelini Giorgia , Mennies Rebekah J. , Kotov Roman , Klein Daniel N. 
Published: February 2021

BackgroundMood‐state biases in maternal reports of emotional and behavioral problems in their children have been a major concern for the field. However, few studies have addressed this issue from a measurement invariance perspective.MethodsUsing data from baseline assessment of the Adolescent Brain Cognitive Development (ABCD) study (n = 8,507 mother–child dyads; youth aged 9–11 years), we examined how dimensions of maternal psychopathology, including internalizing problems, were associated with indices of bias in reports of their children’s dimensions of internalizing, externalizing, neurodevelopmental, detachment, somatoform psychopathology using moderated non‐linear factor analysis. Moderated non‐linear factor analyses examined multiple potential biases in maternal reports of youth psychopathology.ResultsAcross analyses, we found very small magnitudes of associations between dimensions of maternal psychopathology and biases in reports of child emotional and behavioral problems.ConclusionsBased on these results, we find little psychometric evidence for maternal psychopathology biasing reports of child behavior problems.
Effects of sintering time on translucency and color of translucent zirconia ceramics
Authors: Durkan Rukiye , Şimşek Hatice , Deste Gökay Gonca , Yilmaz Burak 
Published: February 2021

AbstractObjectiveTo investigate the effect of sintering time on translucency and color of translucent zirconia ceramics.Materials and MethodsSixty translucent zirconia (5Y‐TZP) specimens (12 × 1.6 mm, Katana (KAT) and NexxZr (NEX)) were divided into six groups (n = 10) according to sintering time; 1, 2 (specified by manufacturer‐control), and 3 hs. Color differences (ΔEab) within same material when sintered using different times and between materials when same sintering time was used were calculated, as well as translucency parameters (TP) after the use of each sintering time. Data for ΔEab and TP were analyzed with two‐way ANOVAs, pairwise comparisons, and Fisher's LSD Test (Post‐hoc).ResultsWhen 1 or 3 h were used, color difference from the color of specimens when manufacturer‐specified time (2 h) was used was similar for both KAT and NEX. ΔEab values of NEX were significantly higher than KAT when sintered for 1 or 3 h (P < 0.001). TP increased for KAT when sintered for 1 h, and was higher than NEX. TP for NEX increased when sintered for 3 h (P < 0.001), but was not significantly different than that of KAT.ConclusionsEffect of 1 or 3‐h sintering on color was similar for both zirconias. For NEX, this effect resulted in greater differences from the color of specimens when manufacturer‐specified time was used. Sintering for 1 h increased the translucency of KAT.Clinical SignificanceWhen high translucency is desired, clinicians may prefer 1‐h sintering for KAT zirconia. When lower translucency is desired, 3‐h sintering for NEX can be used. However, for NEX, the color after 1‐ or 3‐h sintering was different than the color obtained with manufacturer‐specified time, and this difference may affect the final color of restoration compared to the final color when manufacturer‐specified time is used.
Prophylactic clipping after endoscopic mucosal resection of large nonpedunculated colorectal lesions: A meta‐analysis
Authors: Yang Tsung‐Chieh , Wu Yi‐Hui , Lee Pei‐Chang , Chang Chung‐Yu , Lu Hsiao‐Sheng , Chen Yu‐Jen , Huang Yi‐Hsiang , Lee Fa‐Yauh , Hou Ming‐Chih 
Published: February 2021

AbstractBackground and AimIt is not clear whether prophylactic clipping after endoscopic mucosal resection (EMR) of large nonpedunculated colorectal lesions (LNPCLs) prevents delayed bleeding (DB). We aimed to conduct a meta‐analysis to clarify the efficacy of prophylactic clipping in prevention of DB following EMR of LNPCLs.MethodsWe searched PubMed, EMBASE, Web of Science, ScienceDirect, Cochrane Library databases, and ClinicalTrials.gov for studies that compared clipping versus (vs) nonclipping in prevention of DB following EMR of LNPCLs. Pooled odds ratio (OR) was determined using a random effects model. The pooled ORs of DB, perforation, and post‐polypectomy syndrome in the clipping group compared with the nonclipping group comprised the outcomes. Subgroup analyses based on study design, polyp location, and completeness of wound closure were performed.ResultsFive studies with a total of 3112 LNPCLs were extracted. Prophylactic clipping reduced the risk of DB compared with nonclipping (3.3% vs 6.2%, OR: 0.494, P = 0.002) following EMR of LNPCLs. In subgroup analysis, prophylactic clipping reduced DB of LNPCLs at proximal location (3.8% vs 9.8%, P = 0.029), but not of them at distal location (P = 0.830). Complete wound closure showed superior efficacy to prevent DB compared with partial closure (2.0% vs 5.4%, P = 0.004). No benefit of clipping for preventing perforation or post‐polypectomy syndrome was observed (P = 0.301 and 0.988, respectively).ConclusionsProphylactic clipping can reduce DB following EMR of LNPCLs at proximal location. Besides, complete wound closure showed superior efficacy to prevent DB compared with partial closure. Further cost analyses should be conducted to implement the most cost‐effective strategies.
Community screening identifies undiagnosed chronic liver disease in high‐risk populations
Authors: Maher Salim , Dowdell Lisa , Zhang Ling , Zekry Amany 
Published: February 2021

AbstractBackground and AimLiver cirrhosis is the primary risk factor for the development of hepatocellular carcinoma. Most conditions that lead to cirrhosis are treatable, or modifiable. Therefore, a community‐based screening program targeting high‐risk groups was designed for early diagnosis and intervention of liver disease, to offset the rising burden of hepatocellular carcinoma in Australia.MethodsTwo nurse consultants from a tertiary liver center performed community screening of pre‐identified cohorts at risk of viral hepatitis and chronic liver disease, with transient elastography and/or serology testing for chronic hepatitis B virus (HBV) and hepatitis C virus (HCV), in addition to standard blood tests. A positive screening result was defined as any of the following: liver stiffness measurement (LSM) ≥ 9.5 kPa, positive HCV RNA, or positive HBV surface antigen. Individuals who screened positive were linked to the liver center for management.ResultsNine hundred and twenty‐six subjects were screened over a 6‐year period, of which 122/926 (13.2%) had evidence of chronic liver disease. Chronic viral hepatitis was diagnosed in 91 participants (HBV = 23, HCV = 67, and co‐infection = 1), while non‐alcoholic fatty liver disease was diagnosed in 14 participants. Advanced fibrosis (LSM ≥ 9.5 kPa) was detected in 42/866 (4.9%) subjects with available LSM. Loss to follow‐up occurred in 36/91 (39.6%) participants with chronic viral hepatitis.ConclusionsTargeting high‐risk populations for community screening and intervention increases early identification of chronic liver disease. This may reduce the incidence of liver cirrhosis and hepatocellular carcinoma. Loss to follow‐up remains an ongoing challenge, requiring better strategies.
Caregivers’ feeding behaviour, children's eating behaviour and weight status among children of preschool age in China
Authors: Yuan Jing , Jiang Xun , Zhu Tongyu , Zhang Yuhai , Wang Yue , Yang Xianjun , Shang Lei 
Published: February 2021

AbstractBackgroundChildhood overweight and obesity have become significant public health challenges worldwide. The present study aimed to investigate whether caregivers’ feeding behaviour and children's eating behaviour were associated with the weight status of preschool children in China.MethodsA cross‐sectional questionnaire was administered to 912 caregivers of preschool children from April to July 2016. Caregivers’ feeding behaviours were assessed by the Chinese Preschooler's Caregiver Feeding Behaviour Scale. Children's eating behaviours were evaluated using the Chinese Preschooler's Eating Behaviour Questionnaire. After controlling for demographic characteristics, multiple linear regression and logistic regression analyses were performed to evaluate the relationship between caregivers’ feeding behaviour, children's eating behaviour and children's body mass index (BMI).ResultsThe results showed that weight concerns on the part of caregivers (β = 0.53) and food responsiveness on the part of children (β = 0.93) were positively correlated with children's BMI, whereas caregivers’ responsibility for feeding (β = −0.68) and children's external eating (β = −0.53) were negatively correlated with BMI. Among caregiver feeding behaviours, weight concerns [odds ratio (OR) =4.54, p < 0.001] and behaviour‐restricted feeding (OR =0.29, p < 0.001) were positively correlated with children's BMI. A child's food responsiveness (OR =4.04, p < 0.001) was also positively correlated with his/her BMI, whereas the child's satiety responsiveness (OR =0.42, p < 0.001) and emotional eating habits (OR =0.56, p < 0.001) were negatively correlated with overweight/obesity status.ConclusionsOur study demonstrated that children's eating behaviour and caregivers’ feeding behaviour were associated with weight status among preschool children in China. Behaviour interventions on caregivers and their children may prevent or reduce weight problems in preschool children.