bluuebunny/crossref_metadata_2025_split huggingface dataset:
Challenges in Establishing a Coronavirus Disease 2019 (COVID-19) Convalescent Plasma Donation Program in a Multicultural Environment
Authors: Algora Manuel , Mehmood Tori , Madison Debrina L. , AlAmeri Jawahir , Abuzakouk Mohamed , Tagamtam Mylka , Acena Lorlin , Totaan Gerard , Grabski Gloria , Oumeziane Naima , Rajani Pritesh , Taylor Lynzi , Guzman Jorge , AbdelWareth Laila Osama 
Published: August 2021

Context.—
In the face of the coronavirus disease 2019 (COVID-19) pandemic response, it was worthwhile to test the safety and efficacy of COVID-19 convalescent plasma (CCP) transfusion.

Objective.—
To establish a CCP donation program based on the availability of recovered COVID-19 patients and the practical limitations in recruiting clinically valid donors in a multicultural setting.

Design.—
From March to June 2020, we developed a program for collection of COVID-19 CCP as part of the treatment options for patients affected with COVID-19. From an initial population of 3746 candidates, only those with positive polymerase chain reaction results in at least 2 separate tests were considered. This filter reduced the eligible donor pool to 488 patients. After other exclusions were applied, such as language barrier, age, accessibility to donation, and comorbidities, the final count was 267 potentially eligible donors, which represented only 54.7% (267 of 488) of preselected candidates.

Results.—
Eighty donors were called. Approximately a third of the calls provided additional challenges as outlined by the following 4 reasons: limited functional understanding of English; schedule availability due to rotating work timetables; transportation restrictions since public transport services were severely restricted during lockdown; and lost to follow-up. Finally, a total of 38 valid donors participated, upon whom 45 apheresis procedures were performed.

Conclusions.—
As a summary of our experience, we can conclude that despite the limitations we were able to establish an effective program. A total of 90 units of CCP were collected before the pandemic curve began to flatten toward the end of June 2020.
Dialogue entre sciences sociales et théologie dans l’oeuvre de Jean-Marc Ela
Authors: Shimba Gilbert , Loko Marx Sosthène 
Published: August 2021

L’article présente la personne humaine dans la pensée et dans la pastorale de Jean-Marc Ela comme le coeur du dialogue entre sciences humaines/sociales et théologie, et fait apparaître l’ecclésiologie et la théologie de la libération de J.-M. Ela comme les deux lieux par excellence de ce dialogue. En portant une attention lucide aux problèmes de la libération des opprimés, Ela s’oblige à repenser la manière de faire la théologie en Afrique. À bien des égards son épistémologie que nous estimons être en adéquation avec notre temps fait de lui un modèle de théologien africain.
Salut du cosmos et libération anthropologique
Authors: Maloba Grégoire 
Published: August 2021

En Afrique, la nature et l’être humain ont une communauté de destinée, leurs sorts étant liés. Aujourd’hui plus que jamais, la sauvegarde du cosmos et l’engagement pour la promotion humaine sont une des manières concrètes de confesser le Dieu de la vie. Cet article aborde cette question en trois points : les données culturelles disponibles sur le rapport de l’être humain au cosmos, la mémoire chrétienne et finalement le salut du cosmos et la libération de l’Africain. Cette dernière section fait intervenir la pensée de Jean-Marc Ela.
Multi-syndrome, multi-gene risk modeling for individuals with a family history of cancer with the novel R package PanelPRO
Authors: Lee Gavin , Liang Jane W , Zhang Qing , Huang Theodore , Choirat Christine , Parmigiani Giovanni , Braun Danielle 
Published: August 2021

Identifying individuals who are at high risk of cancer due to inherited germline mutations is critical for effective implementation of personalized prevention strategies. Most existing models focus on a few specific syndromes; however, recent evidence from multi-gene panel testing shows that many syndromes are overlapping, motivating the development of models that incorporate family history on several cancers and predict mutations for a comprehensive panel of genes.We present PanelPRO, a new, open-source R package providing a fast, flexible back-end for multi-gene, multi-cancer risk modeling with pedigree data. It includes a customizable database with default parameter values estimated from published studies and allows users to select any combinations of genes and cancers for their models, including well-established single syndrome BayesMendel models (BRCAPRO and MMRPRO). This leads to more accurate risk predictions and ultimately has a high impact on prevention strategies for cancer and clinical decision making. The package is available for download for research purposes at https://projects.iq.harvard.edu/bayesmendel/panelpro.
Industry 4.0
Authors: Demoly Frédéric , André Jean‐Claude 
Published: August 2021

Abstract
The Industry 4.0 concept corresponds to a new way of organizing the means of production. It refers to the generation of connected, robotized, and intelligent factories. With the digital revolution, the boundaries between the physical and digital worlds are shrinking to merge with new interactive modes between operators, machines, and products. Artificial intelligence, 3D printing, virtual reality, digital twin, blockchain, robotics, and digital technologies are transforming the means of production, organization, and business models of companies. If it is a more competitive technological revolution, bearer of numerous innovations, and creator of a new market dynamic, of possible reintegration of manufacturing in Western countries, Industry 4.0 disrupts the world of work as a whole. Indeed, it is the whole system of decision and political regulation of companies, communities, and states (and their natures) of the work relations on the part of the operators which is questioned with an obligation to get out of the processes of individualization and social misanthropy which are taking place at the moment. Transitions are therefore taking place with the search for a possible combination of classical aspects with the immense potential of digital technologies.
Multipronged Fabrication of Co3Se4 Wrapped into N‐Doped Multiwall Carbon Nanotubes Tangled Hollow Dodecahedron Framework for Overall Water Splitting under Benign Condition
Authors: Yang Xiao , Chen Tao , Liu Li , Fu Wensheng 
Published: August 2021

AbstractIn this work, a synergistic strategy is proposed to synthesize a high‐performance bifunctional electrocatalyst (marked as Co3Se4/N‐CNTs) for neutral water splitting, in which Co3Se4 nanoparticles are wrapped into N‐doped multiwall carbon nanotubes assembled hollow dodecahedron framework. The neutral‐oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) catalytic performances of Co3Se4/N‐CNTs are maximally optimized by regulating nanostructure engineering, element doping, and carbon coating. In 1 m phosphate buffer solution (PBS) electrolyte, Co3Se4/N‐CNTs catalyst exhibits superior stability and catalytic activity for OER and HER, yielding a geometrical catalytic current density of 10 and −10 mA cm−2 at rather low overpotentials of 385 and 102 mV, respectively, meanwhile operating continuously for 35 h without obvious polarization increase. It is worth mentioning here, when a neutral electrolyzer is assembled, Co3Se4/N‐CNTs‖ Co3Se4/N‐CNTs cell contributes a high performance for overall water splitting in 1 m PBS electrolyte, delivering a current density of 10 mA cm−2 at a low applied external potential of 1.75 V, and displaying satisfying operation stability without evident deactivation after 35 h. The catalytic performances rival those of catalysts operated under moderate conditions. Consequently, all the merits promise that Co3Se4/N‐CNTs is an attractive bifunctional catalyst for hydrogen fuel production and storage of intermittent renewable energy sources under environmentally friendly conditions.
How women saved agricultural economics
Authors: Offutt Susan , McCluskey Jill 
Published: August 2021

AbstractWomen entered agricultural economics in numbers starting in the 1980s, and their ranks are increasing over time. We make the case that women have increased the relevance in the field of agricultural economics through their diverse interests, perspectives, and experiences. We document how women have changed the profession of agricultural economics in both academia and government. In research, women have expanded the field's treatment of non‐traditional topics such as food safety and nutrition and environmental and natural resource economics. In this sense, women saved the profession from a future as a specialty narrowly focused on agricultural production and markets.
Crop yield response functions in nutrient application: A review
Authors: Dhakal Chandra , Lange Kelly 
Published: August 2021

AbstractThe question of the optimal nutrient application in agricultural production continues to gather attention because of its relevance in increasing the profitability of crop production and protecting the environment. Economically optimal nutrient application decision rules are commonly derived by fitting crop yield functions to nutrients. The choice of the appropriate yield functional form thus is critical for estimating unbiased and more precise nutrient recommendations. This review explores recent developments in yield response functions to the nutrient application. We first introduce the concept of the economic theory of production and yield response functions. We then explain, with mathematical equations, some commonly used functional forms: quadratic response, Mitscherlich–Baule, deterministic, and stochastic plateau functions. We also summarize the strengths and weaknesses of each functional form and its implications for nutrient management strategies from an economic perspective. In recent studies, researchers have suggested that stochastic plateau functional forms, both linear and quadratic, could explain yield response to the nutrient application in a better way. Finally, we recommend fitting stochastic plateau functions in conjunction with carryover information in a dynamic optimization setting may yield more accurate optimal nutrient levels. Future research should continue to investigate whether these functional forms perform better in different crop and soil environments.
Twenty‐year follow‐up of the facial phenotype of Brazilian patients with Sotos syndrome
Authors: Castro Matheus Augusto Araújo , dos Santos Juliana Heather Vedovato , Honjo Rachel Sayuri , Yamamoto Guilherme Lopes , Bertola Débora Romeo , Hurst Anna C. , Chorich Lynn P. , Layman Lawrence C. , Kim Chong Ae , Kim Hyung‐Goo 
Published: August 2021

AbstractSotos syndrome is characterized by overgrowth starting before birth through childhood with intellectual disability and craniofacial anomalies. The majority of patients are large for gestational age with developmental delay or intellectual disability. The majority of cases are caused by pathogenic variants in NSD1. The most consistent physical features in this disorder are facial dysmorphisms including prominent forehead, downslanted palpebral fissures, prognathism with a pointed chin, and a long and narrow face. We present a follow‐up to a cohort of 11 individuals found to harbor heterozygous, pathogenic, or likely pathogenic variants in NSD1. We analyzed the facial dysmorphisms and the condition using retrospective over 20 years. Among these patients, followed in our medical genetics outpatient clinic for variable periods of time, all had a phenotype compatible with the characteristic Sotos syndrome facial features, which evolved with time and became superimposed with natural aging modifications. We present here a long‐term follow‐up of facial features of Brazilian patients with molecularly confirmed Sotos syndrome. In this largest Brazilian cohort of molecularly confirmed patients with Sotos syndrome to date, we provide a careful description of the facial phenotype, which becomes less pronounced with aging and possibly more difficult to recognize in adults. These results may have broad clinical implications for diagnosis and add to the global clinical delineation of this condition.
High‐performance thin‐layer chromatography based approach for bioassay and ATR–FTIR spectroscopy for the evaluation of antioxidant compounds from Asparagus racemosus Willd. aerial parts
Authors: Ashraf Gouhar Jahan , Das Priya , Dua Tarun Kumar , Paul Paramita , Nandi Gouranga , Sahu Ranabir 
Published: August 2021

AbstractAsparagus racemosus Willd. is widely used to combat various diseases owing to its medicinal properties. In this study, arial parts of A. racemosus were investigated for their total phenolic content, total flavonoid content and antioxidative potential. A high‐performance thin‐layer chromatography (HPTLC) method combined with effect‐directed‐analysis was also developed to screen the antioxidant effects of A. racemosus and quantify biologically active compounds on chromatograms from A. racemosus. Total phenolics (154 mg gallic acid equivalent/g), flavonoid contents (497 mg quercetin/g) and IC50 (15.25 μg/ml) were found to be higher in methanolic extract of A. racemosus than in n‐hexane, chloroform and ethyl acetate extracts. HPTLC hyphenated with chemical derivatizations (DPPH•, p‐anisaldehyde/sulfuric acid, and ferric chloride) was used to evaluate antioxidant activity and the presence of phytosterols, terpenoids and polyphenolic contents. The same compounds at 100*retention factor = 58, 68, 74 and 65 in extracts were responsible for antioxidant activity. Hyphenated HPTLC allowed a rapid characterization of the active compound with a combination of effect‐directed‐analysis and attenuated total reflectance–Fourier transform infrared spectroscopy. Spectral analysis of the band from attenuated total reflectance identified myricetin, quercetin, p‐coumaric acid and caffeic acid as responsible for the antioxidant activity.
Phase I study of dose‐escalated stereotactic body radiation therapy for locally advanced pancreatic head cancers: Initial clinical results
Authors: Qing Shuiwang , Gu Lei , Zhang Huojun 
Published: August 2021

AbstractPurposeTo establish the maximum tolerated dose (MTD) of stereotactic body radiation therapy (SBRT) for locally advanced pancreatic head cancers.MethodsA total of 16 patients were included in the single‐institution phase I dose‐escalation study. The initial dose level was 35 Gy in five fractions, doses were then sequentially escalated to 37.5 Gy, 40 Gy, 42.5 Gy, and 45 Gy. The dose‐limiting toxicity (DLT) was defined as III/IV GI (gastrointestinal) toxicity.ResultsA total of 16 patients with locally advanced pancreatic head cancers were analyzed, 14 patients had received gemcitabine or S1‐based chemotherapy. Median OS and LPFS were 14.5 months and 12.5 months, respectively; The OS rates at 1 and 2 years were 68.8% and 25%, respectively. No grade 3 or 4 acute or late GI toxicities were observed. Grade 3 toxicities were observed in four patients with three hematologic toxicities and one biliary obstruction for acute toxicities, G1–2 of GI late toxicity were in 31.25% of patients.ConclusionsSBRT doses ranging from 35 to 45 Gy in five fractions could be given for patients with locally advanced pancreatic head cancers without severe GI toxicities, whereas the side effect of biliary obstruction should be paid more attention.Trial registrationClinical trials:NCT02716207.
Equilibrium Analyses and Kinetics of Carbon Dioxide Methanation Using an Alumina‐Supported Ruthenium Catalyst
Authors: Uysal Duygu 
Published: August 2021

AbstractWith CO2 being accepted as the main cause of the climate change, considerable efforts currently focus on capturing CO2 from major point sources and to store it. Another, better way is to utilize the captured CO2 to produce useful fuels like methane. The Sabatier reaction was studied in this work, using 0.5 % ruthenium on alumina as catalyst. A quartz reactor packed with catalyst particles and placed in a vertical furnace was employed. A stoichiometric ratio of CO2/H2 was used and the temperature was changed between 150 and 400 °C, while the flow rate of the feed gas mixture was varied between 250 and 625 mL min−1, with different amounts of catalyst. The temperature was identified as the major parameter affecting the conversion. Carbon dioxide conversions greater than 85 % were obtained at temperatures higher than 350 °C.
Shortcut Method for Initialization of Dividing‐Wall Columns and Estimating Pareto‐Optimal NQ‐Curves
Authors: Ränger Lena-Marie , Grützner Thomas 
Published: August 2021

AbstractIn early project stages, often no simulation results are available for dividing‐wall columns. Hence, shortcut methods are used to estimate suitable vapor and liquid splits. In a previous paper, it was demonstrated that diagrams are a suited tool to satisfy this need. However, it has turned out that it shows weaknesses for columns with finite or non‐optimal stages. This contribution closes that gap and presents an extended approach to derive suited initial guesses. For this purpose, the original diagram is combined with a heuristic approach to calculate Pareto‐optimal column designs resulting in a stage‐adapted diagram. A comparative study illustrates that the new approach is a powerful tool to generate reliable guesses for multiple dividing‐wall column simulations with finite stage numbers.
Ternary Ni‐based Prussian blue analogue with superior sodium storage performance induced by synergistic effect of Co and Fe
Authors: Zhang Lu‐Lu , Wei Cheng , Fu Xin‐Yuan , Chen Zhao‐Yao , Yan Bo , Sun Pan‐Pan , Chang Kai‐Jun , Yang Xue‐Lin 
Published: August 2021

AbstractPrussian blue analogue Na2Ni[Fe(CN)6] (Ni–PB) has been widely studied as a cathode material for sodium‐ion battery due to its excellent cycling performance. However, Ni–PB has a low theoretical capacity of 85 mAh g−1 because of the electrochemical inertness of Ni. Herein, ternary Ni–PB is successfully synthesized by double doping with Co and Fe at Ni‐site, and the effect of doping with Co and Fe on the electrochemical performance of Ni–PB is systematically investigated through theoretical calculations and electrochemical tests. The first principles calculations confirm that double doping with Co and Fe can significantly reduce the energy barrier and bandgap of Ni–PB. X‐ray diffraction and composition analysis results indicate that ternary NiCoFe–PB composite not only has good crystallinity and high Na content but also has low defects and crystal water. Electrochemical tests reveal that, besides the capacity contribution of high‐spin Co/Fe and low‐spin Fe, Co‐doping enhances the electrochemical activity of low‐spin Fe and Fe‐doping improves the activity of high‐spin Co; moreover, double doping can decrease the diffusion resistance of Na+ ions through solid electrolyte interface film, accelerate the kinetics for both ion diffusion process and Faradic reaction, and increase active sites. Under the synergistic effect of Co and Fe, this ternary NiCoFe–PB exhibits outstanding electrochemical performance with a high initial discharge capacity of 120.4 mAh g−1 at 20 mA g−1 and an extremely low capacity fading rate of 0.0044% per cycle at a high current density of 2 A g−1 even after 10,000 cycles, showing great application potential of ternary NiCoFe–PB in the field of large‐scale energy storage.
N‐Type Quinoidal Polymers Based on Dipyrrolopyrazinedione for Application in All‐Polymer Solar Cells
Authors: Pan Langheng , Zhan Tao , Oh Jiyeon , Zhang Yue , Tang Haoran , Yang Mingqun , Li Mengmeng , Yang Changduk , Liu Xi , Cai Ping , Duan Chunhui , Huang Fei , Cao Yong 
Published: August 2021

AbstractConjugated molecules and polymers with intrinsic quinoidal structure are promising n‐type organic semiconductors, which have been reported for application in field‐effect transistors and thermoelectric devices. In principle, the molecular and electronic characteristics of quinoidal polymers can also enable their application in organic solar cells. Herein, two quinoidal polymers, named PzDP‐T and PzDP‐ffT, based on dipyrrolopyrazinedione were synthesized and used as electron acceptors in all‐polymer solar cells (all‐PSCs). Both PzDP‐T and PzDP‐ffT showed suitable energy levels and wide light absorption range that extended to the near‐infrared region. When combined with the polymer donor PBDB‐T, the resulting all‐PSCs based on PzDP‐T and PzDP‐ffT exhibited a power conversion efficiency (PCE) of 1.33 and 2.37 %, respectively. This is the first report on the application of intrinsic quinoidal conjugated polymers in all‐PSCs. The photovoltaic performance of the all‐PSCs was revealed to be mainly limited by the relatively poor and imbalanced charge transport, considerable charge recombination. Detailed investigations on the structure‐performance relationship suggested that synergistic optimization of light absorption, energy levels, and charge transport properties is needed to achieve more successful application of intrinsic quinoidal conjugated polymers in all‐PSCs.
Monocyclometalated (C N) Gold(III) Metallacycles: Tunable Emission and Singlet Oxygen (1O2) Generation Properties
Authors: Malmberg Robert , Suter Dominik , Blacque Olivier , Venkatesan Koushik 
Published: August 2021

AbstractThe synthesis, characterization and photoluminescent properties of four cyclometalated (C N)‐type gold(III) complexes bearing a bidentate diacetylide ligand, tolan‐2,2’‐diacetylide (tda), are reported. The complexes exhibit highly tunable excited state properties and show photoluminescence (PL) across the entire visible spectrum from sky‐blue (λPL=493 nm) to red (λPL=675 nm) with absolute PL quantum yields (PLQY) of up to 75 % in solution, the highest PLQY found for any monocyclometalated Au(III) complex in solution. As a consequence of the use of the strongly rigidifying diacetylide bidentate ligand, a significant increase in the excited state lifetimes (τ0=16–258 μs) was found in solution and in thin films. The complexes showed remarkable singlet oxygen generation in aerated solution with absolute singlet oxygen quantum yield (ϕ1Δ) values reaching up to 7.5×10−5 and singlet oxygen lifetimes (τ01Δ) in the range of 66–95 μs. Furthermore, the radiative and non‐radiative rates of singlet oxygen were determined using the ϕ1Δ and τ01Δ values and correlations are drawn between the formation of singlet oxygen and its interaction with cyclometalated (C N) gold(III) complexes.