bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis, crystal structure with free radical scavenging activity and theoretical studies of Schiff bases derived from 1-naphthylamine, 2,6-diisopropylaniline, and substituted benzaldehyde
Authors: Oladipo Segun Daniel , Yusuf Tunde Lewis , Zamisa Sizwe Joshua , Tolufashe Gideon Femi , Olofinsan Kolawole Ayodapo , Tywabi-Ngeva Zikhona , Mabuba Nonhlangabezo 
Published: June 2021

Three Schiff bases 1-(4-chlorophenyl)-N-(naphthalen-1-yl)methanimine (1), 1-(4-methoxy phenyl)-N-(naphthalen-1-yl)methanimine (2), and 1-(4-chlorophenyl)-N-(2,6-diisopropyl phenyl)methanimine (3) were synthesized and characterized by elemental analysis, 1H and 13C NMR, FT-IR and UV-Visible spectroscopic techniques. The crystal structure of compound 3 was obtained and it revealed that the compound crystallized in a monoclinic space group P21/n and there exists an intermolecular hydrogen bond in a phenyl-imine form with C-H⋯N. Crystal data for C19H22ClN: a = 7.28280(10) Å, b = 9.94270(10) Å, c = 24.0413(2) Å, β = 97.0120(10)°, V = 1727.83(3) Å3, Z = 4, μ(Mo Kα) = 0.215 mm-1, Dcalc = 1.1526 g/cm3, 14038 reflections measured (12.42° ≤ 2Θ ≤ 52.74°), 3448 unique (Rint = 0.0223, Rsigma = 0.0182) which were used in all calculations. The final R1 was 0.0337 (I≥2u(I)) and wR2 was 0.0927 (all data). The free radical scavenging activities of all three compounds were assayed using DPPH, FRAP, and OH assays. According to results obtained, compound 2 shows effective DPPH- (IC50 = 22.69±0.14 μg/mL), FRAP+ (IC50 = 28.44±0.12 μg/mL), and OH- (IC50 = 27.97±0.16 μg/mL) scavenging activities compared with compounds 1 and 3 but less than standard antioxidant compound Trolox (TRO). Additionally, theoretical calculations for the three complexes were performed by using density functional theory (DFT) calculations at the B3LYP/6-31++G(2d,2p) level in the ground state to obtain an optimized geometrical structure and to perform an electronic, molecular electronic potential surface and natural bond orbital (NBO) analysis. The geometrical calculation obtained was found to be consistent with the experimental geometry. Further analysis was conducted using the in silico technique to predict the drug likeness, molecular and ADME properties of these molecules.
Uso de sugammadex en un paciente con insuficiencia renal crónica
Authors: Erazo Vaca Gabriel Alonso , Calderón Jaime Christian Raúl 
Published: June 2021

Los pacientes con enfermedad renal crónica poseen distintos tipos de factores, tanto fisiológicos como farmacológicos, que alteran la farmacocinética y farmacodinámica de los relajantes musculares no despolarizantes (RMND) lo que hace que la función neuromuscular sea impredecible. La Administración de Alimentos y Medicamentos de los Estados Unidos (FDA) determina como una contraindicación el uso del sugammadex en aquellos pacientes que presenten falla renal crónica asegurando que el aclaramiento de sugammadex se reduce y la vida media se prolonga en estos pacientes; es por este motivo la importancia de su estudio. En el Ecuador, el sugammadex ingresó al Cuadro Nacional de Medicamentos Básicos en el año 2019 para determinados casos especiales. Presentamos el caso de un paciente masculino de 47 años con insuficiencia renal crónica en terapia restitutiva renal que fue sometido a una gastroduodeno anastomosis en Y de Roux más antrectomía laparoscópica, en quien se utilizó exitosamente sugammadex para reversión completa del bloqueo neuromuscular profundo.
Six groundings for Aboriginal and Torres Strait Islander story in the Australian creative writing classroom: Part 1
Authors: Collis Paul , Crawford Jen 
Published: June 2021

‘All Australian children deserve to know the country that they share through the stories that Aboriginal people can tell them,’ write Gladys Idjirrimoonra Milroy and Jill Milroy (2008: 42). If country and story, place and voice are intertwined, it is vital that we make space in Australian creative writing classrooms for the reading and writing of Australian Indigenous story. What principles and questions can allow us to begin? We propose six groundings for this work: 1. Indigenous story is literary history, literary history is creative power. 2. We do culture together: culture becomes in collaboration, conscious or unconscious. 3. There is no such thing as Indigenous story, and yet it can be performed and known. 4. Country speaks, to our conceptions of voice and point of view. 5. History and memory are written in the land and on the body in bodies of practice. 6. Story transmits narrative responsibility. Narrative responsibility requires fierce listening. This two-part paper will discuss each of these groundings as orienting and motivating principles for work we do as teachers of introductory creative writing units at the University of Canberra.
Good Governance Penerapan Prinsip-Prinsip Good Governance dalam Pelayanan BPJS Kesehatan Di Kota Palopo
Authors: Andi Nimah Sulfiani  
Published: June 2021

Abstrak
Pelaksanaan good governance dapat dijadikan sebagai bagian dari upaya untuk melaksanakan asas-asas demokrasi dan demokratisasi, yang merefleksikan dijunjung tingginya aspek pemenuhan hak-hak rakyat oleh penguasa, ditegakannya nilai-nilai keadilan dan solidaritas sosial, serta adanya penegakan HAM dalam berbagai aspek kehidupan Negara. Penelitian ini bertujuan untuk mengetahui dan memahami permasalahan mengenai bagaimana Pelaksanaan Prinsip-prinsip Good Governance dalam pelayanan BPJS Kesehatan di Kota Palopo. Penelitian ini berusaha untuk mengungkap masalah yang berhubungan dengan prinsip- prinsip Good Governance dengan menggambarkan suatu fakta-fakta yang ada di Kantor Cabang BPJS Kesehatan di Kota Palopo. Penelitian ini dilakukan dengan melakukan wawancara langsung dan dokumentasi terhadap sejumlah informan. Teknik analisis data yang digunakan dalam penelitian ini adalah reduksi data, penyajian data, dan penarikan kesimpulan. Penelitian ini menunjukan bahwa Pelaksanaan Prinsip-Prinsip Good Governance dalam Pelayanan BPJS Kesehatan di Kota Palopo belum sepenuhnya terpenuhi. Hal ini terbukti dengan masih adanya keluhan-keluhan dari peserta BPJS Kesehatan mengenai denda pelayanan dan Iuran bagi Pengguna/peserta BPJS Kesehatan di Kota Palopo
Keywords: Pelaksanaan, Pelayanan, BPJS Kesehatan
Assessment of the current status of youth employment in Kazakhstan and the system of its state support
Authors: Doskeyeva G. Zh. 
Published: June 2021

The purpose of the study is to analyze the current state of the youth labor market in Kazakhstan and its main indicators, consider and assess the mechanism of functioning of the system of state support for youth employment; also in reviewing the possibilities of government programs aimed at combating unemployment, including youth unemployment resulting from the COVID-19 pandemic.The research methodology includes statistical and economic, dialectical and comparative methods that were used in writing this scientific article. Since statistical and economic methods are a set of methods used in a comprehensive analysis of the dynamics of the development of certain economic processes, in this article, using the method under consideration, indicators of youth employment in Kazakhstan were grouped, statistical information was developed and analyzed, and also with the help of graphs and diagrams, the analysis results are displayed and assessed the state of the youth labor market. And with the help of the dialectical method, the state of development of economic processes in the labor market, in particular the relationship and interaction between the elements of the mechanism of state support was revealed. Using the comparative method, a comparative analysis of the indicators of the youth labor market and the experience of the functioning of the mechanism of state regulation, as well as the dynamics of changes in the indicators of youth unemployment over a five-year period was carried out.The originality / value of the study lies in a comprehensive analysis of youth employment indicators in Kazakhstan for 2015-2019 and an assessment of the mechanism for the functioning of state programs and other elements of the state regulation system aimed at supporting the youth labor market in the context of the COVID-19 coronavirus pandemic.Findings - main focus andfindings of the article. The research results are related to the analysis of the main indicators of the youth labor market in Kazakhstan and the identification of the main priorities of social policy aimed at improving the system of state support for youth employment.
Assessment of the impact of the employment roadmap on the unemployment rate of the Republic of Kazakhstan: synthetic control method
Authors: Sokira T. S. , Myshbayeva Z. T. 
Published: June 2021

The purpose of the research is to assess the impact of the action plan of the Employment Roadmap on the unemployment rate in Kazakhstan.Methodology. Synthetic Control Method was used in this paper. The method, which compares one or more units exposed to the event and determines what would have happened if the unit had not been treated. In other words, this method creates a weighted combination of control states to create a single «synthetic» control group, in order to approach the counterfactual unit in Kazakhstan in the absence of a plan or Roadmap.The originality / value of the research based on the analysis, panel data from Kazakhstan and 13 donor pool countries for the period 2000-2019 were taken for modeling.Findings: As a result of the study, it was revealed that the unemployment rate would have been 2% higher in 2019 if Kazakhstan had not adopted an action plan in the form of an Employment Roadmap in 2009.
Approaches to changes in business-model by applying digital technologies
Authors: Baigarin T. 
Published: June 2021

The purpose of the study is to disclosure of the essential incentives for digital transformation of traditional business models in the modern conditions of the world economy development and to form a model of digital transformation of the company's trading activities.Methodology. The scientific work is based on the method of theoretical analysis of research by modern authors regarding the features in the field of digital transformation of business models of companies.Originality / value of the research. Values and prerequisites for digital transformation of business models of trade organizations have been determined. The advantages of this transformation in the system of long-term planning and management of the organization are highlighted.Findings. The basic business model of digital transformation has been identified and refined. The specification of the organization's business model key components in the context of digital transformation of operating activities has been determined.
Socially responsible behaviour of Kazakhstani consumers
Authors: Kenebayeva A. S. 
Published: June 2021

Purpose - This study aims to investigate the environmentally and socially-conscious behavior of Kazakhstani consumers in the sector of hospitality and tourism.Methodology - This empirical research is based on the quantitative research method and applies a survey data collection technique. The self-administered questionnaires were distributed among potential consumers relying on a convenience sampling technique. The attitudes of consumers towards responsible business practices of hospitality and tourism firms have been examined by the application of the Pearson Correlation Analysis.Originality / value - The study contributes to the theory building in the field of consumer behavior by responding to a contextual gap in the literature on environmentally and socially-conscious behavior of Kazakhstani consumers focusing on their attitudes towards sustainable business practices in hospitality and tourism and offers practical implications for domestic tourism and hospitality service providers.Findings - The findings show that consumers with higher levels of awareness about sustainable business practices and principles tend to pay higher prices for environmental and socially friendly hospitality and tourism offerings corresponding to sustainability standards and such kind of behavior does not depend on income or education level of individuals.
Analysis of key steps to overcome the crisis in tourism during a pandemic: the experience of Kazakhstan and the United Kingdom
Authors: Nurpeissova A. , Islam D. Md. Z. 
Published: June 2021

Purpose of research. The coronavirus (COVID-19) pandemic lockdown has created a significant threat to the global economy as well as the life of each of us. This paper examines the effect of coronavirus on tourism and proposes a framework of how Kazakhstan can adopt strategies from the international experience (e.g., the UK, Italy, Spain) in order to support tourism sector.Methodology. To achieve the above-mentioned purpose, the study applies qualitative research method that includes in-depth literature reviews of secondary data including research publications (books, peer reviewed journal, reports, government portals, conference papers, online news/article sources etc.).Originality / value. The study includes the analysis of the secondary data concerning the consequences of COVID-19 on economy through comparative analysis between the actions concerning the recovery process of two governments: Kazakhstan and the UK. Based on that the most appropriate recovery steps were presented that would be helpful for tourism support.Findings. This study finds that in the short- term, it might be more appropriate for national economies to prioritize domestic rather than international tourism. Also, in terms of medium to long terms plans, it is important for Kazakhstan learning lessons from international experiences to take actions for the tourism recovery plan, e.g., the support scheme for heritage places and organizations.The article recognizes the practical impact of this review that it can be consulted as an action plan (or handbook) on which steps could be adopted to support tourism. The limitation is that this research is based on the secondary data which is scarce and that the COVID-19 is still happening and the recovery process is an ongoing event, there are not many reliable academic literatures published yet. The findings of the study are expected to aid the academics to conduct future in-depth research.
The concept of product market positioning
Authors: Tleuberdinova A. T. , Zhussupgazina R. R. 
Published: June 2021

The purpose of the article was to reveal the concept of positioning in the market and its main components by identifying the main strategic advantages and properties of this approach. In addition, the article notes the basic rules for positioning the product and highlights the importance of using the positioning map in controlling the position of the product. The article considers the history of the concept of positioning, defines the features of the approaches and definitions of various authors, as well as the analysis of the selection of its criteria. The authors of the article explain the essence of the positioning process, justify the conditions for choosing a positioning strategy.Methodology - The authors used a comparative method of analyzing various positioning strategies and strategic branding, as well as a structural and functional approach in assessing the versatile risky positions of products in the market, in presenting individual positioning processes and describing their stages.Originality / value of the research. The results of the study provide new systematized knowledge that contributes to the further development of the scientific foundations of strategic positioning, increasing the level of scientific research, as well as expanding practical application.Findings - The authors summarize the theoretical and methodological aspects of strategic positioning, based on the systematization of existing practices, the author's interpretation of the concept of "positioning" is given, an author's algorithm is proposed for the actions of companies to develop and implement a positioning strategy based on the need to plan brand development and mandatory analysis of the competitive environment through the definition of attributes and images of competing companies.
Development of corporate social responsibility in Kazakhstan
Authors: Altaibayeva Z. K. , Khamzina S. S. , Baltabayeva A. K. 
Published: June 2021

The purpose of the study is to determine the model of corporate social responsibility in Kazakhstan, as well as to identify problems and development prospects based on the analysis of the promotion of its ideas.Methodology. To determine trends in the development of corporate social responsibility in Kazakhstan, the following approaches have been applied: systemic, dialectical, comparative, territorial-evaluative. The variety of methods is combined into groups: description, comparison, economic and statistical methods, correlation analysis, generalization, other methods and techniques.Originality / value of the research. The article discusses the features of promoting the principles of corporate social responsibility (hereinafter - CSR) in the Republic of Kazakhstan. All components of promoting CSR principles in Kazakhstan are considered as a single system, which defines the conceptual framework, stakeholders in the development of CSR, as well as legal support for its development in the country. The authors characterize the Kazakhstani CSR model of large business and provide examples of the practical implementation of its principles at the present stage. Social investment of subsoil user companies in the territory of their presence in Pavlodar region is analyzed. The considered social investment was carried out within the framework of memorandums of mutual cooperation with local executive authorities.Findings. Based on the study, the authors formulated conclusions about the state of development of CSR business in Kazakhstan.
Corporate social responsibility of the quasi-public sector: principles and processes
Authors: Bekenov N. , Dossova S. 
Published: June 2021

The purpose of the study is to systematize modern ideas about the principles and processes of corporate social responsibility (CSR) in the quasi-public sector.Methodology - formalized methods for the analysis of literary sources - contextual analysis, deduction, adaptation method.Originality / value of the research. Research represents the value for companies of the quasi-public sector of the Republic of Kazakhstan, since it allows to eliminate existing gaps of knowledge (research gaps) in the methodology of corporate social responsibility management. To summarize the quality and effectiveness of CSR, the principles of CSR and the principles of effective management of CSR in the quasi-public sector of the economy are formulated. These principles are implemented in practice through CSR processes and projects.Findings - the model of effective CSR management is proposed, linking the PDCA cycle (Plan-Do-Check-Act), CSR processes and principles of effective CSR management. The proposed model can be taken as a general structural framework of the CSR management system in a quasi-public company and further decompose this system to the level of specific CSR procedures and projects.
INFORMATION OPENNESS AS A MEANS OF INCREASING THE QUALITY OF LEGISLATION IN THE SOCIO-ECONOMIC SPHERE
Authors: Vasilevich G. A. 
Published: June 2021

In modern conditions, the paternalistic type of relations between the state and the person, between the state and society, is being replaced by a new type of relationship between these subjects. The growth of legal culture, legal consciousness of citizens is changing the previously established paradigm of relations: the number of people who recognize themselves as full-fledged subjects of the political process is growing. Sustainable socio-economic development of the state is directly dependent on the extent to which rule-making and law enforcement effectively affect social processes, to what extent the expectations of citizens from the activities of state authorities are justified.The development of information technologies significantly changes the role of citizens, public organizations in making government decisions, and has a significant impact on this process. State administration is carried out through the adoption of legislative acts and law enforcement. Information openness (transparency) of actions in these areas is an important factor in the legitimacy of public authorities.
ОБ ИССЛЕДОВАНИЯХ ГОРОДИЩА БУРНООКТЯБРЬСК (ЖЫЛҚЫШЫТӨБЕ) в 2018–2019 гг.
Authors: Талеев Докей Абдикеримович , Торбеков Ескендірбек Санжарұлы 
Published: June 2021

В статье освещаются результаты раскопок 2018–2019 гг., проводившихся на городище Бурнооктябрьск (Жуалынский р-н, Жамбылская обл.). Раскопом площадью 110×100×18–20 м, заложенном в южной части памятника, установлено наличие двухуровнего строительного комплекса. В ходе раскопок было открыто несколько помещений, стены которых возведены из сырцовых кирпичей. Параметры сохранившихся стен: ширина – 2 м, высота – 3–3,5 м. Археологические материалы, обнаруженные в результате раскопок, датируются I–IV вв. Аналогии находкам, а также характер строительной техники сближает памятник с кауынчинской и отрар-каратауской культурами. Данные, полученные в ходе исследования, позволяют утверждать, что изученный комплекс выполнял роль центра земледельческой общины, населявшей этот регион, в кангюйскую эпоху.
Detección de anticuerpos de Brucella spp. en mataderos del estado Bolívar y Soledad, municipio Independencia, estado Anzoátegui, Venezuela, 2006
Authors: Cermeño Julman Rosiris , De Grazia Ricardo 
Published: June 2021

El objetivo de este estudio fue determinar la seroprevalencia humana y bovina de anticuerpos contra Brucella spp. en mataderos del estado Bolívar y Soledad, municipio Independencia, estado Anzoátegui, Venezuela. Para ello, se realizó un estudio prospectivo y transversal. Previo permiso por escrito de autoridades competentes y consentimiento informado de los trabajadores, se seleccionaron 7 mataderos. Se registraron datos de interés epidemiológico y clínico. Se extrajo sangre por venopunción de personas y bovinos. La demostración de anticuerpos contra Brucella spp. se realizó mediante la prueba DRG® Brucella IgM ELISA en humanos y ELISA competitiva, Brucella-Ab C-ELISA de SVANOVIR®, en animales. Se evaluaron 462 sueros: 159 de trabajadores y 303 de bovinos. La prevalencia de infección en humanos fue 5,6 % y de bovinos 11,2 %; el mayor porcentaje se obtuvo en el grupo de los trabajadores con edades entre 21 y 30 años (a) (P = 0,15) y de sexo masculino (P = 0,34). Siendo más frecuente en el personal que tenía menos de 10 a con riesgo ocupacional (66,6 %); correspondiendo a la ocupación de matarife y despostador el mayor número de casos. El 55,6 % de los trabajadores consumían lácteos sin pasteurizar. Las manifestaciones clínicas fueron inespecíficas: artralgias, cefalea y sudoración nocturna (P > 0,05). Se demuestra que la mayoría de trabajadores de los mataderos evaluados del estado Bolívar y Soledad, municipio Independencia del estado Anzoátegui, están expuestos a múltiples factores de riesgo para contraer brucelosis, sin embargo, la seroprevalencia de anticuerpos de Brucella spp. en ellos fue baja (5,6 %) aunque elevada entre los bovinos estudiados (11,2 %).