bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Protection Conferred by HSD17B13 rs72613567 Polymorphism on Risk of Steatohepatitis and Fibrosis May Be Limited to Selected Subgroups of Patients With NAFLD
Authors: Vilar-Gomez Eduardo , Pirola Carlos J. , Sookoian Silvia , Wilson Laura A. , Liang Tiebing , Chalasani Naga 
Published: September 2021

INTRODUCTION:
Our study aimed to explore how PNPLA3 rs738409 or phenotypic risk factors may moderate the relationship between HSD17B13 rs72613567 and risk of steatohepatitis and fibrosis.

METHODS:
This analysis consisted of 1,153 non-Hispanic whites with biopsy-proven nonalcoholic fatty liver disease enrolled in the nonalcoholic steatohepatitis Clinical Research Network studies. Nonalcoholic fatty liver disease severity was determined by liver histology scored centrally according to the nonalcoholic steatohepatitis Clinical Research Network criteria. Moderation and logistic regression analyses were performed to identify the influence of moderators (PNPLA3 rs738409, age, sex, body mass index, and diabetes) on the relationship between HSD17B13 rs72613567 and risk of steatohepatitis and fibrosis.

RESULTS:

HSD17B13 rs72613567 genotype frequency was as follows: (−/−), 64%; (−/A), 30%; (A/A), 6%. Moderation analysis showed that the protective effect of HSD17B13 rs72613567 A-allele on risk of steatohepatitis remained only significant among patients with PNPLA3 rs738409 genotype CC (β coeff: −0.19, P = 0.019), women (β coeff: −0.18, P < 0.001), patients of age ≥ 45 years (β coeff: −0.18, P < 0.001), patients with body mass index ≥ 35 kg/m2 (β coeff: −0.17, P < 0.001), and patients with diabetes (β coeff: −0.18, P = 0.020). Among women, the protective effect of HSD17B131 rs72613567 A-allele on risk of steatohepatitis was stronger in those aged ≥ 51 years. Logistic regression-based sensitivity analysis including various important subgroups confirmed our observations.

DISCUSSION:
The protection conferred by HSD17B13 rs72613567 A-allele on risk of steatohepatitis and fibrosis may be limited to selected subgroups of individuals who are aged ≥ 45 years, women and have class ≥ 2 obesity or diabetes, and those with PNPLA3 rs738409 CC genotype.
The Social Engagement to Agricultural Issues using Social Network Analysis
Authors: Widiyanti Tanty Yanuar , Adji Teguh Bharata , Hidayah Indriana 
Published: September 2021

Twitter is one of the micro-blogging social media which emphasizes the speed of communication. In the 4.0 era, the government also promotes the distribution of information through social media to reach the community from various lines. In previous research, Social Network Analysis was used to see the relationship between actors in a work environment, or as a basis for identifying the application of technology adoption in decision making, whereas no one has used SNA to see trends in people's response to agricultural information. This study aims to see the extent to which information about agriculture reaches the community, as well as to see the community's response to take part in agricultural development. This article also shows the actors who took part in disseminating information. Data was taken on November 13 to 20, 2020 from the Drone Emprit Academic, and was taken limited to 3000 nodes. Then, the measurements of the SNA are represented on the values of Degree Centrality, Betweenness Centrality, Closeness Centrality, and Eigenvector Centrality. @AdrianiLaksmi has the highest value in Eigenvector Centrality and Degree Centrality, he has the greatest role in disseminating information and has many followers among other accounts that spread the same information. While the @RamliRizal account ranks the highest in Betweenness Centrality, who has the most frequently referred information, and the highest Closeness Centrality is owned by the @baigmac account because of the fastest to re-tweet the first information.
On Waiting Willfully in Urban Uganda: Toward an Anthropology of Pace
Authors: Eisenstein Anna 
Published: September 2021

Women in Uganda strategically time their entry into married motherhood in relation to others with whom they want to be connected. Although much of the burgeoning literature on “waithood” laments global youth’s delayed entry into social adulthood, I show that women in urban Uganda intentionally pause, slowing down their movement through the life course to cultivate networks of interdependence that will propel them not only forward through the life course but also upward socioeconomically. The logics and practices by which they pace themselves point beyond a neoliberal conception of time and agency, instead highlighting the heightened importance of divine connections and social coordination under increasingly capitalist and urban conditions. The lens of pace helps bring into view the situated, multilayered, relational projects of moving through life with others.

EKIHANDIIKO OMUBUGUFU

Abakazi omuri Uganda nibetebekanisiza gye obwiire bw’okutaaha omubushweere n’obuzaire waaba n’ogyeragyeranisa naabo abubarikweenda kwegaita/kuba nabo. N’obu ebihaandiiko ebirikweyongyera kukanya ebirikukwaata aha bunyeeto biraabe nibyooreka okutoonzya ahabw’eminyeeto kukyerererwa kukura, ninyoreka ngu abakazi omumyaanya ekurakureine omuri Uganda nibariindaho bakigyendereire, bakyeendeeza ahamigyendere omumituurire yaabo kwenda ngu babaase kwombeka emikago y’okuhweerahweerana etarikubayaamba kwongyera kubutuura emituurire yaabo kwonka kureka na n’okwongyera kubatunguura omubyentaatsya. Enteekateeka hamwe n’emitwaarize eyibarikutwaazamu n’ehingura ahanyetegyereza y’obweire hamwe n’obugabe bw’okwehitsyaho ebyetaago eya abakurakureine, beitu byongyera kumurika ekyetaago kihaango ky’okumanya ebyenyikiriza hamwe n’okutuuragye n’abaantu omumbeera z’obushuubuzi hamwe n’entunguuka ebiriyo nibikanya. Ekitangaazo ky’emitwarize nikiyaamba kureeba omubury’obuhikire, entebekanisa zitarikushushwana z’okubaasa kutuuragye nabaandi.
The Role of Ethnobiology in Responding to Current Problems in the Management of Biological Resources and Ecosystems in Indonesia
Authors: Purwanto Yohanes 
Published: September 2021

ABSTRACT
Ethnobiology is defined as the scientific study of the cultural knowledge possessed by various communities. It is also related to the techniques used in the management of biological resources, and the position of those communities in their cosmic cultural vision. This study discusses the role of development and perspectives of ethnobiology in Indonesia for managing the diversity of biological resources and their ecosystems sustainably. The results of ethnobiological studies can describe the problems, potentials, and opportunities to develop the diversity of biological natural resources and their ecosystems as a source of life for the community in a sustainable manner. The current problems faced in the management of biological resources are socio-culture, limitations and disregard for science and technology, weak institutions, inability to arrange spatial planning, inaccurate determination of development priorities, misperceptions and misconception about biodiversity, policy fragmentation and inability to manage biological resources, enforcement of certification, and climate change. Therefore, ethnobiological studies must be able to reveal the benefits and potentials of biological resources and their ecosystem and provide a foundation for the management and advancement of biodiversity sustainably to increase national prosperity and development.

Keywords: Ethnobiology, Biodiversity, Management, Sustainability
Psychometric Properties of Object Relation Scale: Factor Structure and Relationship to Mental Health
Authors: Uji Masayo , Kawaguchi Makiko 
Published: September 2021

Background: Object Relations Scale (ORS: Iume, Hirai, Aoki & Baba, 2006) was developed for accessing an individual’s object relation pattern. It consists of five domains: Insufficiency of Intimacy, Superficiality in Interpersonal Relations, Egoistic Manipulation, Excessive Need for Identification, and Abandonment Anxiety. However, its factor structure using confirmatory factor analysis (CFA) is still undetermined.
Purpose: This study aims at evaluating the psychometric properties of ORS, in particular, confirming its factor structure using CFA, and examining the relationship of object relation maturity, to mental health as well as to psychological distress.
Methods: The subjects of this study were 547 medical college students in Japan. CFA were conducted in order to determine the best fit model. The relationships of maturity level of one’s object relation pattern to his/her mental health as well as psychological distresses were examined by t-tests.
Results: A four-factor model, a modified version of the original five-factor model showed the best fit. Among the four factors, three were those included in the original model. They were Insufficiency of Intimacy, Superficiality in Interpersonal Relations, and Abandonment Anxiety. The last factor consisted of items originally included in the remaining two factors, Egotistic Manipulation and Excessive Need for Identification. Each ORS subscale score positively correlated with that of mental health problems as well as those of psychological distresses of one or more domains at significant levels.
Conclusion: The four-factor model, which does not necessarily negate the original five-factor model proposed by Iume et al., showed the best fit. Immaturity and instability in object relation relationship contributed to a variety of distresses as well as poor mental health.
First Wave Feminism: Craftswomen in Plato’sRepublic
Authors: Hulme Emily 
Published: September 2021

AbstractAncient Athenian women worked in industries ranging from woolworking and food sales to metalworking and medicine; Socrates’ mother was a midwife. The argument for the inclusion of women in the guardian class must be read in light of this historical reality, not least because it allows us retain an important manuscript reading and construe the passage as relying on an inductive generalization rather than a possibly circular argument. Ultimately, Plato fails to fully capitalize on the resources he has for a more egalitarian conclusion than the one he settles on, which regards women as “lesser than” yet “similar to” men.
Did Gary Johnson and Jill Stein Cost Hillary Clinton the Presidency? A Counterfactual Analysis of Minor Party Voting in the 2016 US Presidential Election
Authors: Devine Christopher J. , Kopko Kyle C. 
Published: September 2021

Abstract
Hillary Clinton won the national popular vote for president in 2016, but lost to Donald Trump in the Electoral College. Trump’s margin of victory in several decisive battleground states was smaller than the combined vote for the two leading minor party candidates: Gary Johnson, of the Libertarian Party, and Jill Stein, of the Green Party. The perception that Johnson and Stein “stole” the 2016 presidential election from Clinton is widespread, and potentially consequential for future minor party candidacies, but it has not yet been rigorously tested. In this article, we extend the analysis of minor party voting in the 1992 election from Lacy, D., and B. C. Burden. 1999. “The Vote-Stealing and Turnout Effects of Ross Perot in the 1992 U.S. Presidential Election.” American Journal of Political Science 43 (1): 233–55, by using data from the 2016 Cooperative Congressional Election Study to estimate a multinomial probit model of voting behavior—including outcomes for vote choice and abstention—and calculate the predicted probabilities that Johnson and Stein voters would have voted for another candidate or abstained from voting, had one or both of these candidates been excluded from the ballot. We then reallocate Johnson’s and Stein’s votes accordingly, to estimate Clinton’s and Trump’s counterfactual vote shares nationally and within key battleground states. Our analysis indicates that Johnson and Stein did not deprive Clinton of an Electoral College majority, nor Trump the legitimacy of winning the national popular vote. We estimate that most Johnson and Stein voters would have abstained from voting if denied the choice to vote for their preferred candidate, and that most of Johnson’s remaining voters would have supported Trump.
Allocating Unlimited Money: What Explains Super PAC Spending in Congressional Elections?
Authors: Rocca Michael S. , Clay Jared W. 
Published: September 2021

Abstract
How do Super PACs allocate their resources? The question is both timely and relevant, particularly as we reflect on the ten-year anniversary of the Citizens United ruling. Super PACs now outspend – sometimes by huge margins, as in the 2016 presidential election – all other groups’ independent expenditures including those of parties, unions, and 501(c) organizations. The issue is especially important in congressional politics, where Super PACs have an opportunity to shape the institution every two years through congressional elections. Utilizing outside spending data from the Center for Responsive Politics, we analyze four U.S. House election cycles since the Supreme Court’s landmark 2010 Citizens United ruling (2012–2018). The likelihood that Super PACs invest in a race is strongly determined by the electoral context, even after controlling for the legislative influence of the incumbent member of Congress.
新马华语史的一个断面:以《蕉风》(1955–1970)为语料的考察
Authors: 李计伟  , 刘燕婧  
Published: September 2021

Abstract
Based on Chao Foon (1955-1970), a Chinese literature Journal of Singapore and Malaysia, this paper describes the written features of Singaporean and Malaysian HUAYU in detail from the aspects of parts of speech and syntactic structures. In terms of research methods, based on the “chronological features” of this period, on the one hand, we explore the origin and follow the trail of the development and evolution, and find that some features have existed in Nanyang HUAYU since the late Qing Dynasty, and have their own development and changes. Some features correspond to the early modern Chinese, and the vast majority of "chronological features" still exist in today's Singaporean and Malaysian HUAYU; On the other hand, we make a horizontal comparison with modern Chinese in the same period through which we can not only confirm the origin of some features of HUAYU, but also provide an observation perspective for the study of the centennial changes of modern Chinese.
Emerging contributions of formyl peptide receptors to neurodegenerative diseases
Authors: Busch Lukas , Vieten Stefan , Brödel Susan , Endres Kristina , Bufe Bernd 
Published: September 2021

Abstract
Inflammation is a central element of many neurodegenerative diseases. Formyl peptide receptors (FPRs) can trigger several receptor-dependent signal transduction pathways that play a key role in neuroinflammation and neurodegeneration. They are chemotactic receptors that help to regulate pro- and anti-inflammatory responses in most mammals. FPRs are primarily expressed in the immune and nervous systems where they interact with a complex pattern of pathogen-derived and host-endogenous molecules. Mounting evidence points towards a contribution of FPRs – via neuropathological ligands such as Amyloid beta, and neuroprotective ligands such as Humanin, Lipoxin A4, and Annexin A1 – to multiple pathological aspects of neurodegenerative diseases. In this review, we aim to summarize the interplay of FPRs with neuropathological and neuroprotective ligands. Next, we depict their capability to trigger a number of ligand-dependent cell signaling pathways and their potential to interact with additional intracellular cofactors. Moreover, we highlight first studies, demonstrating that a pharmacological inhibition of FPRs helps to ameliorate neuroinflammation, which may pave the way towards novel therapeutic strategies.
Numerical simulation and microtomography study for drying a deformable isodiametric-cellular food
Authors: Pérez Santiago Angel , Sandoval Torres Sadoth , Léonard Angélique , Plougonven Erwan , Díaz-González Mario , Hernández-Bautista Emilio 
Published: September 2021

AbstractThe aim of this work is the simulation of volumetric strain of tuberous crop during drying. We propose a poroelastic model for predicting the drying kinetics and volume loss of potato cubes during convective drying. The Biot’s theory of poroelasticity was used, which considers the Lamé parameters, Young’s modulus and Poisson’s ratio. Drying kinetics and volumetric strain were modeled and compared versus experimental data. An X-ray microtomograph coupled with image analysis was used to visualize the shape and size of the samples during drying. Drying experiments were conducted at 50, 60 and 70 °C, 20% RH, with an air velocity of 1 and 2 m/s. The drying process was interrupted several times to perform tomographic acquisitions. We found a period of ideal shrinkage, nevertheless, the volumetric strain reveals a kinetic behavior over time. The model computes the volumetric strain, which describes correctly the experimental data obtained by microtomography.
Nitisinone treatment during two pregnancies and breastfeeding in a woman with tyrosinemia type 1 – a case report
Authors: Zöggeler Thomas , Ramoser Gabriele , Höller Alexander , Jörg-Streller Monika , Janzen Nils , Ramoni Angela , Scholl-Bürgi Sabine , Karall Daniela 
Published: September 2021

Abstract

Objectives
Tyrosinaemia type 1, an inherited disorder of tyrosine metabolism, is usually treated with a tyrosine-defined diet and since 2000 with nitisinone. So far, data about effects of nitisone during pregnancy and breastfeeding are rare. This is the first report of two pregnancies in a patient with tyrosinaemia type 1 while under treatment with nitisinone.

Case presentation
We here present a 20-year-old female patient with tyrisonemia type 1 receiving treatment with nitisinone and a tyrosine-defined diet since she was diagnosed with tyrosinaemia type 1 at the age of 18 months. During two pregnancies blood concentrations of tyrosine, succinylacetone and nitisinone were measured regularly. Neither infant has tyrosinaemia type 1 and both showed an initial increase in concentrations of tyrosine, succinylacetone and nitisinone. All three metabolites dropped within two weeks after birth. Both were exclusively breastfed for about two weeks. Both children show age-appropriate physical and mental development.

Conclusions
Nitisinone therapy during pregnancy and the short breastfeeding period did not result in adverse events in our patient or her children. Regular assessments of tyrosine, succinylacetone and nitisinone should be made during pregnancy and the breastfeeding period in both the mother and the infant. For better understanding, in principle, all cases of pregnancy and breastfeeding with tyrosinemia type 1 should be assessed and followed to further evaluate the implications of tyrosinaemia type 1 and its treatment during pregnancy. Additionally, even though experience with breastfeeding is limited, medication with nitisinone is safe and there is no reason to consider breastfeeding unsafe or to not recommend it.
Marangoni convection in layers of water-based nanofluids under the effect of rotation
Authors: Bakhsh Abeer H. , Abdullah Abdullah A. 
Published: September 2021

Abstract
A linear stability analysis is performed for the onset of Marangoni convection in a horizontal layer of a nanofluid heated from below and affected by rotation. The top boundary of the layer is assumed to be impenetrable to nanoparticles with their distribution being determined from a conservation condition while the bottom boundary is assumed to be a rigid surface with fixed temperature. The motion of the nanoparticles is characterized by the effects of thermophoresis and Brownian diffusion. A modification model is used in which the effects of Brownian diffusion and thermophoresis are taken into consideration by new expressions in the nanoparticle mass flux. Also, material properties of the nanofluid are modelled by non-constant constitutive expressions depending on nanoparticle volume fraction. The steady-state solution is shown to be well approximated by an exponential distribution of the nanoparticle volume fraction. The Chebyshev-Tau method is used to obtain the critical thermal and nanoparticle Marangoni numbers. Different stability boundaries are obtained using the modified model and the rotation.
Peritoneal loose body presenting as a hepatic mass: A case report and review of the literature
Authors: Wen Yang , Shang Min-jie , Ma Yan-qing , Fang Song-hua , Chen Yuan 
Published: September 2021

Abstract
Peritoneal loose body (PLB) is a rare clinical entity. It is generally agreed that the most common origin of the loose bodies is appendix epiploica. We here report a case of PLB that looks like a “boiled egg,” which was misdiagnosed preoperatively as a lesion of hepatic origin and was confirmed by operation and postoperative pathology. PLBs are rare entities, a good understanding of their specific imaging features can help prevent misdiagnosis, but sometimes an accurate preoperative diagnosis is still difficult to achieve. Exploratory laparoscopy is a recommended method for management of PLBs.
Campo del Cielo – an Iron Meteorite found in Argentina
Authors: Haubner R. , Strobl S. 
Published: September 2021

Abstract
Fragments of the “Campo del Cielo” meteorite were first reported by conquistadores in Argentina in as early as 1576. This meteorite belongs to the group of iron meteorites and is classified as a group IA coarse octahedrite. The use of meteoric iron to make objects of daily use or hunting weapons in prehistoric times is only confirmed by very few finds. Metallographic examinations were performed to assess if it was realistic and in fact feasible to process meteoric iron.
The bulk of the examined “Campo del Cielo” meteorite fragment found in Argentina is kamacite (α-Fe) with approx. 5.3 wt.% of dissolved Ni. Graphite was also detected in addition to various non-metallic phases. Due to high temperatures during processing, graphite can dissolve and a steel microstructure would form as a result.
Using a sentiment analysis for the examination of tourism blogs – a step by step methodological reflection process
Authors: Szepannek Gero , Westphal Laila , Gronau Werner , Lehmann Tine 
Published: September 2021

Abstract
The article at hand is driven by a methodological interest in the opportunities and challenges of applying an automated text mining approach, particularly a sentiment analysis on various tourism blogs at the same time. The study aims to answer the question to what extent advanced computational methods can improve the data acquisition and analysis of unstructured data sets stemming from various blogs and forums. Furthermore, the authors intend to explore to what extent the sentiment analysis is able to objectify the qualitative results identified by an earlier analysis by the authors using content analysis done by thematic coding. For the purpose of the specific tourism research question in this paper a new approach is proposed, which consists of a combination of sentiment analyses, supervised learning, and dimensionality reduction in order to identify terms that strongly load on specific emotions. The contribution indicates on the one hand, that advanced computational methods have their own specific constraints, but on the other hand, are able to provide a richer and deeper analysis following a quantitative approach. Several issues have to be taken into account, such as data protection constraints, the need for data cleaning, such as word stemming, dimension reduction, such as removal of custom stop words, and the development of descent ontologies. On the other hand, the quantitative method also provides, due to its standardised procedure, a less subjective insight in the given content, but is not less time consuming than traditional content analysis.