bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prenatal attachment: using measurement invariance to test the validity of comparisons across eight culturally diverse countries
Authors: Foley Sarah , Hughes Claire , Murray Aja Louise , Baban Adriana , Fernando Asvini D. , Madrid Bernadette , Osafo Joseph , Sikander Siham , Abbasi Fahad , Walker Susan , Luong-Thanh Bao-Yen , Vo Thang Van , Tomlinson Mark , Fearon Pasco , Ward Catherine L. , Valdebenito Sara , Eisner Manuel 
Published: February 2021

AbstractStudies in high-income countries (HICs) have shown that variability in maternal-fetal attachment (MFA) predict important maternal health and child outcomes. However, the validity of MFA ratings in low- and middle-income countries (LMICs) remains unknown. Addressing this gap, we assessed measurement invariance to test the conceptual equivalence of the Prenatal Attachment Inventory (PAI: Muller, 1993) across eight LMICs. Our aim was to determine whether the PAI yields similar information from pregnant women across different cultural contexts. We administered the 18-item PAI to 1181 mothers in the third trimester (Mean age = 28.27 years old, SD = 5.81 years, range = 18–48 years) expecting their first infant (n = 359) or a later-born infant (n = 820) as part of a prospective birth cohort study involving eight middle-income countries: Ghana, Jamaica, Pakistan, Philippines, Romania, South Africa, Sri Lanka and Vietnam. We used Multiple Group Confirmatory Factor Analyses to assess across-site measurement invariance. A single latent factor with partial measurement invariance was found across all sites except Pakistan. Group comparisons showed that mean levels of MFA were lowest for expectant mothers in Vietnam and highest for expectant mothers in Sri Lanka. MFA was higher in first-time mothers than in mothers expecting a later-born child. The PAI yields similar information about MFA across culturally distinct middle-income countries. These findings strengthen confidence in the use of the tool across different settings; future studies should explore the use of the PAI as a screen for maternal behaviour that place children at risk.
Healing of intrabony defects following regenerative surgery by means of single-flap approach in conjunction with either hyaluronic acid or an enamel matrix derivative: a 24-month randomized controlled clinical trial
Authors: Pilloni Andrea , Rojas Mariana A. , Marini Lorenzo , Russo Paola , Shirakata Yoshinori , Sculean Anton , Iacono Roberta 
Published: February 2021

Abstract
Objectives
The aim of this randomized controlled clinical trial was to compare the clinical outcomes obtained in intrabony defects following regenerative periodontal surgery using the single-flap approach (SFA) in conjunction with either hyaluronic acid (HA) or enamel matrix derivative (EMD).

Materials and methods
Thirty-two intrabony defects in 32 healthy subjects were randomly assigned: HA (test group) or EMD (control group). Clinical attachment level (CAL), probing depth (PD), gingival recession (REC), and bleeding on probing (BOP) were recorded at baseline,12, 18, and 24 months after surgery.

Results
At 24 months, both treatments resulted in statistically significant clinical improvements evidenced by PD-reduction and CAL-gain (p<0.001). The mean CAL-gain was 2.19±1.11 mm in the test and 2.94±1.12 mm in the control sites (p=0.067). PD-reduction was statistically significantly higher for the control group (4.5±0.97 mm) than the test group (3.31±0.70 mm), (p=0.001). CAL-gain ≤ 3 mm was observed in 87.5% and in 62.5% of the test and control sites, respectively. Test sites showed slightly lower REC values than the control sites. No statistically significant differences were found for BOP between treatments.

Conclusions
The present findings indicate that both treatments led to statistically significant clinical improvements compared to baseline, although the application of EMD resulted in statistically significantly higher PD-reduction compared to the use of HA.

Clinical relevance
The use of HA in conjunction with a SFA resulted in significant PD-reduction and CAL-gain, pointing to the potential clinical relevance of this material in regenerative periodontal surgery.
Microbiology of parapharyngeal abscesses in adults: in search of the significant pathogens
Authors: Klug Tejs Ehlers , Greve Thomas , Andersen Camilla , Hahn Pernille , Danstrup Christian , Petersen Niels Krintel , Ninn-Pedersen Mirjana , Mikkelsen Sophie , Pauli Søren , Fuglsang Simon , Døssing Helle , Christensen Anne-Louise , Rusan Maria , Kjeldsen Anette 
Published: February 2021

AbstractWe aimed to describe the microbiology of parapharyngeal abscess (PPA) and point out the likely pathogens using the following principles to suggest pathogenic significance: (1) frequent recovery, (2) abundant growth, (3) growth in relative abundance to other microorganisms, (4) percentage of the isolates recovered in both absolute and relative abundance, (5) more frequent recovery in PPA pus compared with tonsillar surface and tissue. Comprehensive bacterial cultures were performed on specimens obtained from adult patients (n = 60) with surgically verified PPA, who were prospectively enrolled at five Danish ear-nose-throat departments. The prevalent isolates (in PPA pus) were unspecified anaerobes (73%), non-hemolytic streptococci (67%), Streptococcus anginosus group (SAG) (40%), Corynebacterium spp. (25%), Neisseria spp. (23%), Fusobacterium spp. (22%), Fusobacterium necrophorum (17%), Prevotella spp. (12%), and Streptococcus pyogenes (10%). The bacteria most frequently isolated in heavy (maximum) growth were unspecified anaerobes (60%), SAG (40%), F. necrophorum (23%), and Prevotella spp. (17%). The predominant microorganisms (those found in highest relative abundance) were unspecified anaerobes (53%), SAG (28%), non-hemolytic streptococci (25%), F. necrophorum (15%), S. pyogenes (10%), and Prevotella spp. (10%). Four potential pathogens were found in both heavy growth and highest relative abundance in at least 50% of cases: F. necrophorum, Prevotella spp., SAG, and S. pyogenes. SAG, Prevotella spp., F. necrophorum, S. pyogenes, and Bacteroides spp. were recovered with the same or higher frequency from PPA pus compared with tonsillar tissue and surface. Our findings suggest that SAG, F. necrophorum, Prevotella, and S. pyogenes are significant pathogens in PPA development.
The experiences of foundation doctors with dyspraxia: a phenomenological study
Authors: Walker Eleanor , Shaw Sebastian C. K. , Reed Malcolm , Anderson John L. 
Published: February 2021

AbstractDyspraxia, otherwise known as Developmental Coordination Disorder (DCD), is a specific learning difficulty (SpLD). Its main difficulties manifest as problems with motor coordination, organisation, academic and social difficulties. There are now more students arriving at university with SpLDs, and, therefore, a similar rise may be expected within medical education. There has been no previous research focusing on dyspraxia in doctors. An interpretive phenomenological approach was used. Six UK foundation schools disseminated the announcements. Three participants took part in loosely structured telephone interviews regarding their experiences of undertaking medical school and foundation school with dyspraxia. These were transcribed verbatim and then thematically analysed. The themes could be split into two main categories: “Weakness and Coping Strategies” and “Perspectives of Dyspraxia”. “Weakness” included: clumsiness, organisation and needing extra time. The participants focused on their “Coping Strategies” that included: Ensuring safety, adapted learning preferences and external support. “Perspectives of Dyspraxia” included: diagnosis, career choice, stigma, “normalisation” and the “difference view” or “medical deficit” view of dyspraxia. Doctors with dyspraxia often mask their difficulties through sophisticated coping strategies. These were determined and hardworking individuals who believe that their dyspraxia was a positive aspect of their identity, adopting a “difference view”. They felt further education is needed about dyspraxia to change the perceived stigma. There is now a need for further research in this area.
Exploring assumptions in crop breeding for climate resilience: opportunities and principles for integrating climate model projections
Authors: Whitfield Stephen , Chapman Sarah , Mahop Marcelin Tonye , Deva Chetan , Masamba Kennedy , Mwamahonje Andekelile 
Published: February 2021

AbstractCrop breeding for resilience to changing climates is a key area of investment in African agricultural development, but proactively breeding for uncertain future climates is challenging. In this paper, we characterise efforts to breed new varieties of crops for climate resilience in southern Africa and evaluate the extent to which climate model projections currently inform crop breeding activity. Based on a survey of seed system actors, we find that the prioritisation of crops and traits is only informed to a limited extent by modelled projections. We use an ensemble of CORDEX models for mid and end of century for southern Africa to test some of the assumptions that underpin current breeding activity, particularly associated with breeding for reduced durations and drought tolerance in maize, and demonstrate some of the ways in which such projections can help to inform breeding priorities and agenda setting (e.g. through the case of assessing cassava toxicity risk). Based on these examples, we propose five potential applications of climate models in informing breeding priorities. Furthermore, after unpacking the sources of uncertainty within the presented model projections, we discuss general principles for the appropriate use of climate model information in crop breeding.
Insights into early ontogenesis: characterization of stress and development key genes of pikeperch (Sander lucioperca) in vivo and in vitro
Authors: Schäfer Nadine , Kaya Yagmur , Rebl Henrike , Stüeken Marcus , Rebl Alexander , Nguinkal Julien A. , Franz George P. , Brunner Ronald M. , Goldammer Tom , Grunow Bianka , Verleih Marieke 
Published: February 2021

AbstractThere are still numerous difficulties in the successful farming of pikeperch in the anthropogenic environment of various aquaculture systems, especially during early developmental steps in the hatchery. To investigate the physiological processes involved on the molecular level, we determined the basal expression patterns of 21 genes involved in stress and immune responses and early ontogenesis of pikeperch between 0 and 175 days post hatch (dph). Their transcription patterns most likely reflect the challenges of growth and feed conversion. The gene coding for apolipoprotein A (APOE) was strongly expressed at 0 dph, indicating its importance for yolk sac utilization. Genes encoding bone morphogenetic proteins 4 and 7 (BMP4,BMP7), creatine kinase M (CKM), and SRY-box transcription factor 9 (SOX9) were highly abundant during the peak phases of morphological changes and acclimatization processes at 4–18 dph. The high expression of genes coding for peroxisome proliferator-activated receptors alpha and delta (PPARA,PPARD) at 121 and 175 dph, respectively, suggests their importance during this strong growth phase of juvenile stages. As an alternative experimental model to replace further in vivo investigations of ontogenetically important processes, we initiated the first approach towards a long-lasting primary cell culture from whole pikeperch embryos. The present study provides a set of possible biomarkers to support the monitoring of pikeperch farming and provides a first basis for the establishment of a suitable cell model of this emerging aquaculture species.
The “first match” between high-tech entrepreneurial ventures and universities: the role of founders’ social ties
Authors: Colombo Massimo G. , Guerini Massimiliano , Rossi-Lamastra Cristina , Bonaccorsi Andrea 
Published: February 2021

AbstractThis paper studies the collaborations between entrepreneurial ventures and universities by investigating the“first match”, namely, the probability that a given entrepreneurial venture, which has never established university collaborations before, forms a collaboration with a given university (out of all the possible collaborations it might have formed). Expanding on the literature about university–industry collaborations, we argue that the formation of the first match is socially bounded. Specifically, we contend that individual social ties, which the founders of an entrepreneurial venture have formed with the personnel of a given university as they worked there, increase the probability of a first match because these ties reduce the costs and increase the benefits of forming a collaboration (H1). We also hypothesize that geographical (H2) and cognitive proximity (H3) between entrepreneurial ventures and universities influence these costs and benefits, thus moderating the relation sub H1. Econometric estimations on a large set of dyads, which represent realized and potential first matches between Italian high-tech entrepreneurial ventures and universities, support our hypotheses.
Temporal trends in the Colonisation of the Pacific: Palaeodemographic Insights
Authors: McFadden Clare , Walter Richard , Buckley Hallie , Oxenham Marc F. 
Published: February 2021

AbstractThe colonisation of eastern parts of the Pacific Islands was the last phase in the preindustrial expansion of the human species. Given the scale and challenges of the endeavour it is unsurprising that scholars have long been interested in understanding the conditions that drove and supported the exploration and settlement of this vast region. There has been speculation as to the influence of demographic factors, either as drivers or in some way regulating the rate and success of human expansion, but testing this has proven challenging. This study evaluates two hypotheses of population dynamics: the adaptation/resilience hypothesis, which proposes that populations respond to localised environmental conditions and changes in subsistence strategy, technology, differences in pathogen loads, and other events that occur at different times in different places; and the temporal hypothesis, which proposes that populations respond to major events such as climate change that occur in a region at an absolute point in, or over an absolute period of, time (noting that the two hypotheses are not mutually exclusive). Applying new methods for estimating the rate of natural population increase from human skeletal remains, this study utilised 23 samples to evaluate trends in population increase following the human expansion into the region. The results indicate a trend in population growth following colonisation, with initially high population growth, followed by a significant decrease and subsequently an increase in growth rates. The lack of a temporal trend may represent a high degree of heterogeneity in the impacts of climate change on individual archipelagos and islands.
Autochthony Belief and Making Amends to Indigenous Peoples: The Role of Collective Moral Emotions
Authors: Nooitgedagt Wybren , Martinović Borja , Verkuyten Maykel , Jetten Jolanda 
Published: February 2021

AbstractIntergroup relations in settler societies have been defined by historical conflict over territorial ownership between indigenous peoples and settler majorities. However, the indigenous groups were there first, and first arrival is an important principle for assigning ownership to a group. In two studies among Australians of Anglo-Celtic origin (N = 322 and N = 475), we argued and found that the general belief in entitlements for first comers (i.e. autochthony) is related to more support for reparations in terms of apology and instrumental compensation for Aborigines, as well as to less topic avoidance. We further proposed that the group-based emotions of collective guilt, moral shame and image shame account for these associations. We found that majority members who endorsed autochthony belief experienced more guilt (Study 1 and 2), moral shame (Study2) and image shame (Study 2). In turn, guilt and moral shame were related to more support for reparations and less topic avoidance, whereas image shame was related to more topic avoidance, thereby partially suppressing the negative association between autochthony belief and topic avoidance. Our research points at the importance of considering autochthony belief and different types of moral emotions in research on past transgressions and current attempts to restore social justice for indigenous peoples.
The non-existence of institutional facts
Authors: Dörge Friedrich Christoph , Holweger Matthias 
Published: February 2021

AbstractThat certain paper bills have monetary value, that Vladimir Putin is the president of Russia, and that Prince Philip is the husband of Queen Elizabeth II: such facts are commonly called ‘institutional facts’ (IFF). IFF are, by definition, facts that exist by virtue of collective recognition (where collective recognition can be direct or indirect). The standard view or tacit belief is that such facts really exist. In this paper we argue, however, that they really do not—they really are just well-established illusions. We confront realism about IFF with six criteria of existence, three established and three less so but highly intuitive. We argue that they all tell against the existence of IFF. An obvious objection to IFF non-realism is that since people’s behaviour clearly reflects the existence of IFF, denying their existence leaves an explanatory gap. We reject this argument by introducing a variant of the so-called ‘Thomas Theorem,’ which says that when people collectively recognize a fact as existing, they largely behave accordingly, regardless of whether that fact really exists or not.
Description of a Multi-faceted COVID-19 Pandemic Physician Workforce Plan at a Multi-site Academic Health System
Authors: Pendharkar Sachin R. , Minty Evan , Shukalek Caley B. , Kerr Brendan , MacMullan Paul , Lail Parabhdeep , Cheema Kim , Alimohamed Nimira , Allen Thomas , Vlasschaert Meghan E. O. , Kachra Rahim , Ma Irene W. Y. , Johannson Kerri A. , Gibson Paul S. , Elliott Meghan J. , Papini Adam , Smith Stephanie , Lemaire Jane , Ruzycki Shannon M. , Hunter Angela , Desjardins-Kallar Wendy , Schaefer Jeffrey P. , Zarnke Kelly B. , Bharwani Aleem , Fabreau Gabriel E. 
Published: February 2021

Abstract
Background
The evolving COVID-19 pandemic has and continues to present a threat to health system capacity. Rapidly expanding an existing acute care physician workforce is critical to pandemic response planning in large urban academic health systems.

Intervention
The Medical Emergency-Pandemic Operations Command (MEOC)—a multi-specialty team of physicians, operational leaders, and support staff within an academic Department of Medicine in Calgary, Canada—partnered with its provincial health system to rapidly develop a comprehensive, scalable pandemic physician workforce plan for non-ventilated inpatients with COVID-19 across multiple hospitals. The MEOC Pandemic Plan comprised seven components, each with unique structure and processes.

Methods
In this manuscript, we describe MEOC’s Pandemic Plan that was designed and implemented from March to May 2020 and re-escalated in October 2020. We report on the plan’s structure and process, early implementation outcomes, and unforeseen challenges. Data sources included MEOC documents, health system, public health, and physician engagement implementation data.

Key Results
From March 5 to October 26, 2020, 427 patients were admitted to COVID-19 units in Calgary hospitals. In the initial implementation period (March–May 2020), MEOC communications reached over 2500 physicians, leading to 1446 physicians volunteering to provide care on COVID-19 units. Of these, 234 physicians signed up for hospital shifts, and 227 physicians received in-person personal protective equipment simulation training. Ninety-three physicians were deployed on COVID-19 units at four large acute care hospitals. The resurgence of cases in September 2020 has prompted re-escalation including re-activation of COVID-19 units.

Conclusions
MEOC leveraged an academic health system partnership to rapidly design, implement, and refine a comprehensive, scalable COVID-19 acute care physician workforce plan whose components are readily applicable across jurisdictions or healthcare crises. This description may guide other institutions responding to COVID-19 and future health emergencies.
Effect of Different SiO2 Polymorphs on the Reaction Between SiO2 and SiC in Si Production
Authors: Folstad Marit Buhaug , Ringdalen Eli , Tveit Halvard , Tangstad Merete 
Published: February 2021

Abstract
This work investigates the phase transformations in silica (SiO2) during heating to a target temperature between 1700 °C and 1900 °C and the effect of SiO2 polymorphs on the reduction reaction 2SiO2 + SiC = 3SiO + CO in silicon production. Different heating rates up to target temperature have been used to achieve the different compositions of quartz, amorphous silica and cristobalite. The different heating rates had a minor effect on the final composition, and longer time at temperatures > 1400 °C were necessary to achieve greater variations in the final composition. Heating above the melting temperature gave more amorphous silica and less cristobalite, as amorphous silica also may form from β-cristobalite. Isothermal furnace experiments were conducted to study the extent of the reduction reaction. This study did not find any significant difference in the effects of quartz, amorphous silica or cristobalite. Increased temperature from 1700 °C to 1900 °C increased the reaction rate.
Suicidal ideation and associated factors among school-going adolescents in rural Ghana
Authors: Quarshie Emmanuel Nii-Boye , Odame Samuel Kofi 
Published: February 2021

AbstractSuicidal ideation is a critical risk for attempted suicide and eventual suicide. Little is known about suicidal ideation among rural adolescents in most sub-Saharan African countries. We aimed to estimate the 12-month prevalence of suicidal ideation and to describe some of the common and gender-specific associated factors among in-school adolescents in rural Ghana. We conducted a cross-sectional survey involving a random sample of 1101 in-school adolescents aged 10–19 years in a rural district in Eastern Ghana. The Suicidal Behavior Questionnaire-Revised was used to assess suicidal ideation. Overall, 25.1% participants (95% CI = 22.5–27.7), representing 28.3% females (95% CI = 24.7–32.2) and 21.5% males (95% CI = 18.0–25.2) reported suicidal ideation during the previous 12 months. Females who experienced personal and interpersonal adversities mainly outside the family context were likely to report suicidal ideation, while suicidal ideation among males was associated with conflict with parents. Regardless of gender, adolescents who reported exposure to a friend’s attempted suicide were about two times more likely to report suicidal ideation. The prevalence of suicidal ideation among adolescents in rural Ghana compares with in-school estimates from other countries within sub-Saharan Africa, but also underscores the need for targeted and universal prevention programmes and intervention efforts to mitigate the potential transition from suicidal ideations to suicidal attempts and eventual deaths by suicide among rural adolescents.