bluuebunny/crossref_metadata_2025_split huggingface dataset:
Histological Study of Effect of Oral Administration of Monosodium Glutamate (MSG) on Duodenum of Wistar Rats
Authors: Rahayu Mulyati Sri , Perwira Awaludin Lambang Rizki , Wahyuni Sri 
Published: December 2024

Monosodium glutamate (MSG) is a widely marketed flavor enhancer that is regularly consumed. MSG is toxic to several organs including the small intestine. Previous studies have reported the effects of high doses of MSG; however, these findings are not directly applicable to equivalent human intakes. This study aimed to investigate the effect of MSG on the duodenum in rats administered with human average daily intake (ADI). Twenty-four adult male Wistar rats weighing 150–250 g at the age of 8-12 weeks were divided into four experimental groups (n = 6): normal control group (C), group 1 (0.378 mg/g b.wt), group 2 (0.756 mg/g b.wt), and group 3 (1.512 mg/g b.wt) oral MSG per day for 21 days. Duodenaltissue was dissected and stained with hematoxylin and eosin (HE) for histological examination. Data analysis was performed using the Kruskal-Wallis test (p 0.05). The average height of the villus was calculated for each group: control (1047.40 ± 158.0 µm), Group 1 (850.68 ± 202.38 µm), Group 2 (906.29 ± 416.63 µm), and Group 3 (877.55 ± 154.65 µm). There was a difference in the height of the villi between all groups; however, there was no statistically significant difference compared with the control group (p = 0.384). The control group showed a normal appearance of the duodenal mucosa without inflammatory cells. In contrast, the treatment group showed inflammatory cell infiltration and lacked distinct brush-border structures. Our study showed that administration of MSG at an estimated dose of human ADIresulted in histological damage to the duodenum.
EKSTRAKSI DAUN PULUTAN (Urena lobata Linn) DENGAN METODE SONIKASI DAN UJI AKTIVITAS ANTIBAKTERINYA
Authors: Fadillah Ummu Farah 
Published: December 2024

Penelitian ini bertujuan untuk mengkaji pengaruh konsentrasi etanol dalam proses ekstraksi daun pulutan terhadap aktivitas antibakteri, khususnya terhadap Propionibacterium acne, Staphylococcus aureus dan Staphylococcus epidermidis. Ekstraksi dilakukan dengan etanol pada konsentrasi 30%, 60%, dan 90%. Hasil penelitian memperlihatkan konsentrasi etanol berbanding lurus dengan diameter daya hambat, meskipun rendemen yang diperoleh menurun. Rendemen tertinggi diperoleh dengan etanol 30% (36,36%), diikuti oleh etanol 60% (19,27%), dan terendah dengan etanol 90% (8,48%). Uji antibakteri menunjukkan kemampuan tertinggi terhadap S. aureus dan S. epidermidis dicapai dengan ekstrak etanol 90% pada konsentrasi 500 mg/mL. Penelitian ini menegaskan bahwa konsentrasi pelarut berperan penting dalam mengekstraksi senyawa bioaktif yang efektif dalam menekan perkembangan bakteri.
The Effect of Lockdown During the Covid-19 Pandemic on Bird Species Richness at IPB Dramaga Campus
Authors: Hidayat Haris  Akbar , Dewanti Anindya , Tirtaningtyas Fransisca , Mulyani Yeni Aryati 
Published: December 2024

IPB Dramaga Campus in Bogor has been recognized to hold a high diversity of birds, while at the same time is also experiencing disturbance due to human activities. During the covid-19 pandemic in 2020-early 2022, most human activities on campus were decreased. Observations made during lockdown indicated that birds were seen more easily in various habitats on campus. The objective of this study was to describe bird species richness and composition before the period of lockdown and after the pandemic (post-lockdown). Bird surveys were conducted monthly in 2019 and from January to May 2023 to obtain a bird species list. Mist nets were set up monthly for 3 months in 2019 and 2023 to obtain demographic data. Descriptive analysis was conducted by comparing the results with previous data collected by Uni Konservasi Fauna (UKF) and Cikabayan Bird Banding Club (CBC). The number of bird species between the two periods did not differ significantly; there were 66 species in while in 2023 there were 60 species. In both periods bird species composition was dominated by the family of Cuculidae, and the dominant feeding guild was insectivores.
Pengaruh Citra Merek, Persepsi Harga dan Kualitas Pelayanan terhadap Minat Beli Ulang Produk Es Teh Indoneisa
Authors: Andini Zagita , Shiratina Aldina 
Published: December 2024

Penelitian ini bertujuan untuk mengetahui pengaruh citra merek, persepsi harga, dan kualitas pelayanan terhadap minat beli ulang produk Es Teh Indonesia. Populasi dalam penelitian ini adalah seluruh konsumen yang pernah melakukan pembelian dan mengetahui Es Teh Indonesia. Sampel yang digunakan adalah yang pernah membeli Es Teh Indonesia, Konsumen yang mengunjungi Es Teh Indonesia gerai Srengseng, konsumen yang pernah membeli Es Teh Indonesia minimal 2 kali pembelian. Sampel Penelitian yang digunakan sebanyak 140 responden menggunakan metode Purposive Sampling. Metode pengumpulan data menggunakan metode survei, dengan instrumen penelitian adalah kuesioner. Metode analisis data menggunakan Partial Least Square. (PLS 4.0). Desain penelitian ini adalah penelitian kausal dengan metode analisis data menggunakan PLS SEM. Penelitian ini membuktikan bahwa Citra Merek berpengaruh Positif dan signifikan terhadap Minat Beli Ulang, Persepsi Harga berpengaruh Positif dan signifikan terhadap Minat Beli Ulang dan Kualitas Pelayanan berpengaruh Positif dan signifikan terhadap Minat Beli Ulang.
Kata Kunci: Citra Merek, Persepsi Harga, Kualitas Pelayanan, dan Minat Beli Ulang
Pengaruh Pemberian Ekstrak Peperomia pellucida Terhadap Penurunan Ekspresi Tumor Necrosis Factor Alpha (TNF-α) Pada Ginjal Tikus Wistar Jantan Yang Mendapat Pajanan Asap rokok
Authors: Nerawati Maria Fransiska , Farida Anggraini Soetedjo  , Heru Setiawan  
Published: December 2024

Pendahuluan: Pajanan asap rokok menyebabkan stres oksidatif dan respons inflamasi melalui radikal bebas. Tumor Necrosis Factor Alpha adalah sitokin proinflamasi yang memperburuk peradangan ginjal. Pemberian antioksidan dan antiinflamasi eksogen diharapkan dapat mencegah cedera ginjal akibat pajanan asap rokok. Peperomia pellucida atau sirih cina, merupakan tumbuhan yang dikenal memiliki aktivitas antioksidan dan antiinflamasi. Penelitian ini bertujuan mempelajari efek ekstrak Peperomia pellucida terhadap penurunan ekspresi TNF-α pada ginjal tikus wistar jantan yang terpajan asap rokok. Metode: Penelitian true eksperimental ini menggunakan metode post-test only control group design dengan subjek tikus wistar jantan berusia 8-12 minggu yang diperoleh dari Laboratorium Hewan Coba Fakultas Kedokteran Universitas Wijaya Kusuma, Surabaya. Sampel terdiri dari 20 ekor tikus yang memenuhi kriteria inklusi dan eksklusi, dengan berat badan sekitar 180-200 gram. Data dianalisis menggunakan uji Mann-Whitney. Hasil: Uji Mann-Whitney menghasilkan perbedaan signifikan antara kelompok P1 dan P2, dengan nilai signifikan 0,025. Hal ini menunjukan bahwa pemberian ekstrak Peperomia pellucida secara signifikan mampu menurunkan ekspresi TNF-α pada ginjal tikus yang terpajan asap rokok. Kesimpulan: Pemberian ekstrak Peperomia pellucida dengan dosis 400 mg/KgBB/hari dapat menurunkan ekspresi TNF-α pada ginjal tikus wistar jantan yang terpajan asap rokok.
Pengaruh Ekstrak Etanol Lada Hitam (Piper nigrum L) dan Serai (Cymbopogon citratus) terhadap Kadar Trigliserida pada Rattus Novergicus yang Hiperkolesterolamia
Authors: Silitonga Evanri Matthew , Noer Kumala Indahsari  , Herliani Olivia 
Published: December 2024

Pendahuluan: Hiperkolesterolemia merupakan salah satu faktor risiko penyebab terjadinya penyakit jantung koroner. Di Indonesia, terdapat sekitar 36 juta penduduk atau sekitar 18% dari penduduk Indonesia yang menderita hiperkolesterolemia. Hiperkolesterolemia merupakan penyebab mortalitas yang tinggi yaitu sekitar 4 juta kematian per tahun. Kolesterol merupakan suatu komponen penting dalam tubuh manusia yang memiliki peran vital dalam berbagai fungsi. Kolesterol memengaruhi fluiditas membran sel dan berfungsi sebagai prekursor hormon steroid. Sebagian besar kolesterol dalam tubuh dibentuk melalui dua jalur utama, yaitu jalur eksogen yang berasal dari makanan dan jalur endogen yang disintesis di dalam tubuh. Lada hitam (Piper Nigrum L) telah lama digunakan dalam pengobatan tradisional untuk mengatasi berbagai masalah kesehatan, termasuk gangguan lipid. Kedua tumbuhan ini mengandung senyawa-senyawa aktif seperti polifenol dan flavonoid yang memiliki potensi dalam menurunkan kadar trigliserida. Cymbopogon citratus adalah tanaman tahunan aromatik yang penting secara ekonomi dari keluarga Poaceae. Tanaman ini ditanam di seluruh dunia dan memiliki catatan aplikasi terapi ekstensif selama satu abad dalam pengobatan tradisional dan Ayurveda di sejumlah negara.
Metode: Desain penelitian yang digunakan pada penelitian ini adalah eksperimental laboratorium dengan rancangan penelitiannya adalah post-test only controlled group design. Pada penelitian ini terbagi menjadi 6 kelompok, yaitu 3 kelompok kontrol berupa kelompok kontrol negatif (K-), kelompok kontrol positif (K+) dan kelompok perlakuan sebanyak 4 kelompok (P1, P2, P3, dan P4).
Hasil: Hasil didapatkan rata-rata pengaruh ekstrak yang terbentuk pada kontrol negatif memiliki rata-rata sebesar 36,51, kontrol positif memiliki rata-rata sebesar 108.80, lada hitam 200mg memiliki rata-rata sebesar 66,02, lada hitam 500mg memiliki rata-rata sebesar 36,72, serai 200mg sebesar 50,26, dan serai 500mg sebesar 47,71.
Kesimpulan: Berdasarkan data statistik maka ekstrak lada hitam yang dapat menurunkan kadar trigliserida lebih baik adalah lada hitam dengan kadar 200mg sedangkan untuk ekstrak serai yang dapat menurunkan kadar trigliserida lebih baik adalah serai dengan kadar 200 mg.
ANALYSIS OF THE DEPOSITIONAL CONDITIONS OF THE MIOCENE SALIFEROUS FORMATION OF THE TRANSCARPATHIAN TROUGH
Authors: Shekhunova Stella , Siumar Natalia , Stadnichenko Svitlana , Aleksieienkova Maryna 
Published: December 2024

Based on the results of the generalization and interpretation of geological and geophysical materials of the Miocene saliferous formation of the Transcarpathian Trough, a GIS-integrated database was designed and used to apply a new technique for structural models development. In particular, models of the depths and thickness of the saliferous formation within the Chop-Mukachevo and Solotvyno depressions were developed. The obtained models were analyzed to assess the degree of reliability and the verification of the boundary of the saliferous formation was done.
Mantra penyambutan kelahiran anak pada ritual belian melas suku Dayak Tunjung
Authors: Putri Nina Queena Hadi , Sulistyowati Endang Dwi , Saputra Marselinus Juan , Rokhmansyah Alfian 
Published: December 2024

Mantra dipercaya oleh masyarakat pendukungnya memiliki kekuatan gaib, kesaktian, dapat menyembuhkan penyakit, dan menghindari gangguan roh-roh gaib. Penelitian ini bertujuan untuk mendeskripsikan fungsi mantra belian melas suku Dayak Tunjung di Kampung Ngenyan Asa, Kabupaten Kutai Barat. Metode yang digunakan dalam penelitian ini adalah metode penelitian etnografi dengan pendekatan kualitatif yang dipaparkan secara deskriptif. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah teknik observasi, wawancara terstruktur, dan dokumentasi. Teknik analisis data yang digunakan adalah reduksi data, transkrip data, penyajian data, penarikan kesimpulan. Dari hasil penelitian mantra pada belian melas berfungsi sebagai pengendali sosial (nasihat), pengingat (peringatan toleransi, dan alat komunikasi pemeliant dengan para roh-roh agar tidak mengganggu, menyakiti dan kembali kepada anak keluarga), sarana untuk berdoa dengan roh-roh, dan sarana pelestarian budaya lokal.
A Systematic Review of Bioremediation of Soil Pollution Using Different Types of Bacteria 2015-2023
Authors: Abdul Muhsin Zahraa A. , Mutar Samara , Mohammed Nour ulhuda G. 
Published: December 2024

Soil contamination from industrial and agricultural activities is a widespread problem threatening environmental and public health. Bioremediation employing bacteria shows promise as a sustainable cleanup approach. To systematically review published research from 2015-2023 on bioremediating soil pollution using diverse bacterial strains. A comprehensive search of Web of Science, PubMed and Scopus identified studies meeting inclusion criteria: focused on bacterial bioremediation of polluted soils under controlled conditions and reported quantitative outcomes. The 87 relevant studies were analyzed covering remediation of petroleum hydrocarbons, heavy metals, pesticides and emerging contaminants using bacteria. Key genera included Pseudomonas, Bacillus, Rhodococcus for hydrocarbons and metal-resistant bacteria. Most optimized conditions in microcosms, with some field pilots showing decontamination over months. This review confirms bacteria effectively biodegrade various soil pollutants under optimized conditions. Continued research is warranted to address technical challenges for field-scale implementation and expand the range of treatable contaminants. Overall, bacterial bioremediation represents a promising sustainable solution for soil remediation.
Isolation of Lactobacillus rhamnosus from Human Breast Milk and Study their Susceptibility to Antibiotics
Authors: Alquraishi Shaimaa Ghanim Abdullah 
Published: December 2024

Probiotics have an assortment of implementations in various domains. Nowadays, probiotics are used as a method to prevention many disorders and treat diseases. In this study was isolated L.rhamnosus from breast milk with the intention to studying their properties as probiotics in view of important it on infant health. 24 positive samples out of 108 have been isolated and identification by using biochemical tests and molecular diagnosis using the 16S rRNA gene. This research revealed relationship between pregnant period and existence of L.rhamnosus (P-Value < 0.05). this relationship refers to the milk of mothers who have completed nine months of pregnancy had high percent of L.rhamnosus(75%) compared to mothers who delivery in seventh or eighth month of pregnancy whereas there no relationship ( P-Value > 0.05)between existence of L.rhamnosus and mother age, infant age and type of delivery. The probiotic potential was assessed by determining antibiotic susceptibility through the disc diffusion method. Among the 24 isolates, resistance was observed to vancomycin and intermediate resistance to penicillin, streptomycin and clindamycin respectively, while susceptibility was shown to ampicillin, tetracycline, chloramphenicol and gentamycin respectively. Notably, none of the isolates exhibited hemolytic activity. Based on these findings, the isolated Lactobacillus rhamnosus displayed promising probiotic characteristics, highlighting human milk as a potential source of these beneficial bacteria
Study the Effect of Cerium Oxide Nanoparticles on Hematological Parameters and Liver Tissue in Rats by two Different ways: Oral Administration and Intravenous Injection
Authors: Turki Maab 
Published: December 2024

The objective of this work was to examine the acute toxic effects of cerium oxide nanoparticles (CeO2 NPs) on adult male white rats and comparison between orally administration and injection. Fifty experimental animals were randomly divided into two groups, the Orally group and the injection group, each group contains 4 Subgroup with 5 animals for each Subgroup as follows: Orally group: The first group T1 (as positive control group) that administrated 1 ml of distilled water, T2,T3,T4,T5 treated with CeO2 NPs with 50 mg\ml, 250 ml, 500 ml, and 1000 ml, respectively. In addition Injection group:- T1 (as positive control group) and T2,T3,T4, T5, treated with 50 ml, 250 ml , 500 ml, and 1000 ml, of CeO2 NPs respectively. This study demonstrated no effect of CeO2 NPs on hematological parameters at p-value >0.05, While increase ALT and AST in both groups treated with of CeO2 NPs at p-value <0.05. Furthermore cause congestion of the central vein with degeneration of hepatocytes in T4. While in high dose don’t show any effect. This study simultaneously concluded the cytotoxic effect in low dose on liver tissue while no effect in high dose. Also this study concluded no effect on hematological parameters.
Detection of some virulence genes of Staphylococcus aureus that caused Infective Endocarditis
Authors: Abdul hameed Namuq Noorjan 
Published: December 2024

Infective Endocarditis (IE), first documented over 350 years ago, is condition characterized by infection of the endocardial membrane of the heart. The clinical presentations of irreversible endocarditis (IE) can affect all organ systems, with the cardiac manifestations including valve vegetation, abscess, periannular extension of infection, and myopericarditis. 230 Blood sample were collected from Infective Endocarditis patients, blood culture used for bacterial growth and identification of bacterial species were completed by microscopic examination, culture characteristics, and biochemical tests, and the use of the Vitek 2 diagnostic system for final identification of the isolated bacteria. Antibiotic sensitivity test for S. aureus were performed by disk diffusion method , mecA and sarA genes were detected by PCR. 51 positive culture for bacterial growth and 18 were S. aureus bacteria, most of Staph aureus were resistant to ampicillin (100%), amoxiclav (83.3%)and pencillin(94.4%) while they were highly sensitive to Azithromycin, Cefotaxime, Ceftriaxone, Gentamicin, Imipenem, Levofloxacin, Amikacin, and Trimethoprim, which reached 72.22%, 72.22%, 83.33%, 88.89%, 83.33%, and 88.8% 9, 83.33%, 83.33%, 72.22%, and 88.89%, respectively. mecA gene were found in (42,8%)of S. aureus isolates while sarA gene were found in (64.2%). S. aureus have many virulence factors genes that contributed in the infective Endocarditis infection and they were resistant to many antibiotics due to these genes.
Evaluation of latent-transforming growth factor beta-binding protein, dopamine and serotonin in patients with chronic epilepsy according to disease type and body mass index
Authors: Dhamin shakir Saba 
Published: December 2024

The study aimed to evaluate some biochemical, immunological, physiological and neurotransmitter variables in chronic epilepsy patients. The study comprised 60 patients with epilepsy and a control group of 30 healthy persons, aged between 15 and 60 years. The investigation involved quantifying the amounts of dopamine, serotonin, latent-transforming growth factor beta-binding protein 1 (LTBP1), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT). The findings of the present investigation indicated the following: A notable reduction (p≤0.01) in the levels of latent transforming growth factor binding proteins (LTBP1) relative to the control group. A notable elevation (p≤0.01) in the levels of dopamine, alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) was observed in comparison to the control values. A substantial elevation (p≤0.05) in serotonin levels was observed relative to the control data. This study indicated a reduction in the levels of LTBP1. The concentration of dopamine, serotonin, AST, ALT, and ALP is elevated in patients with persistent epilepsy compared to healthy individuals.
Effect of gout milk and bromelain on liver and hematological parameters in male rats
Authors: MOHAMED SAEED ABDULHADI ALI 
Published: December 2024

Peptic ulcers occur owing to peptic acid damage to the gastrointestinal tract, resulting in the erosion of the mucosal layer, with lesions exceeding 3-5 mm in depth. Aim of the study: The main objectives of this study were to evaluate the effect of fortified goat milk on the blood, liver and hormone profile in rats by estimating them in blood plasma. To know the effect of goat milk fortified with bromelain on the stomach and intestines affected by ulcers by comparing it with the treatment of omeprazole. The research was conducted from September 2023 to January 2024. A sample of 30 sexually mature male animals was used, randomly distributed into six groups of similar weights, and each group included five rats obtained from the animal house of the College of Veterinary Medicine at Tikrit University. Division of rats occure as A1 healthy control group (untreated and provided only with water and food throughout the experiment period). A2 The infected control group (infected with a gastrointestinal ulcer after being given an oral dose of acetic acid). A3 given an oral dose of goat's milk. A4 given an oral dose of goat's milk fortified with bromelain enzyme. A5 given an oral dose of bromelain enzyme .A6 Group oral administration of omeprazole. The present study showed decrease RBC , Hb, and PCV in T2 group as compared with control(T1), while increased in T3,T4,T5, but no difference between T1 and T6. As for platelets increase in T1, while no differences between T1,T3,T4,T5,and T6. Both GPT and GOT increase in T2 as compared with T1 , while no differences in T3,T4,T5,T6 as compared with T1. Furthermore decrease T3,T4,T5,T6 as compared with T2. As for GPT decrease in T3,T4,T5,T6 as compared with T1 and T2. This study concluded the protective effect of goat milk on rats infected with peptic ulcer and synergical combination of both bromelain and gout milk were more effective than alone. This study also concluded increase PCV,Hb,RBC, and decrease GOT,and GPT in peptic ulcer.
Normy nieludzkiej niepełnosprawności. Przypadek wierszy Anny Augustyniak
Authors: Jarzyna Anita 
Published: December 2024

Odwołując się do rozpoznań Sunaury Taylor dotyczących niepełnosprawności jako konstruktu narzucanego także pozaludzkim gatunkom, proponuję krytyczną lekturę tomu wierszy Anny Augustyniak pt. Między nami zwierzętami (2020), który spotkał się ze względnie przychylną recepcją, ale też nie został do tej pory przeczytany z pozycji konsekwentnie nieantropocentrycznych. Dowodzę, że opisując z całą brutalnością rozmaite praktyki przemocy wobec zwierząt, autorka nie tylko sięgnęła po zużyte chwyty, lecz przede wszystkim dalece zmarginalizowała i zawłaszczyła perspektywę nie-ludzkich ofiar, wyraźnie eksponując własne przeżycia. Co skutkuje normalizacją wiktymizujących i ableistycznych wyobrażeń o zwierzętach jako pozbawionych autonomii, słabych, zależnych i wreszcie niepełnosprawnych istotach, przeciwdziała więc wyzwoleniu ich na ich własnych zasadach.
Trauma, queerowanie tożsamości i naturalistyczny obraz wsi w debiutanckiej powieści M.L. Rijnevelda Niepokój przychodzi o zmierzchu
Authors: Stoch Magdalena 
Published: December 2024

Autorka podejmuje próbę refleksji nad reprezentacją obszarów wiejskich i nienormatywnych, nastoletnich biografii, w debiutanckiej powieści M.L. Rijnevelda Niepokój przychodzi o zmierzchu (2021). Wykorzystując kategorie analityczne wyprowadzone z badań nad dzieciństwem, traumą, wiejskością, płcią i seksualnością, autorka pokazuje, jak metro- i heteronormatywność oraz doświadczenie traumy wpływają na kondycję bohaterów literackich oraz ich zdolność do przeciwstawiania się przemocy