bluuebunny/crossref_metadata_2025_split huggingface dataset:
Economic Costs of Delayed Diagnosis of Functional Motor Disorders: Preliminary Results From a Cohort of Patients of a Specialized Clinic
Authors: Tinazzi Michele , Gandolfi Marialuisa , Landi Stefano , Leardini Chiara 
Published: December 2021

Background: Functional motor disorders (FMDs) are prevalent and highly disabling conditions in young adults that can result in reduced independence. Despite advances in diagnosis and treatment, the economic burden of FMDs is largely unknown.Objective: This pilot retrospective study provides a real-world overview of the economic costs related to delayed diagnosis of FMDs from a cohort of patients of a specialized clinic in Italy, based on Italian healthcare costs.Methods: Sociodemographic data, clinical history, healthcare service utilization, and associated direct costs were collected for a period of up to 5 years before a definite diagnosis of FMDs in 40 patients.Results: The mean time lag between the onset of FMDs symptoms and diagnosis was 6.63 years (±8.57). The mean annual use of recourses per patient was three specialist visits (95% CI 2.4–3.4) and three diagnostic examinations (95% CI 2.2–3.6) that made up a total of six investigations and over seven (95% CI 5.5–9.7) rehabilitation contacts per year per patient were used before a diagnosis of FMDs was established. In more than 50% of the cases, patients had been hospitalized or made an ER visit at least once before receiving the correct diagnosis. The average annual costs for delayed diagnosis, taking into account only direct healthcare costs (without medications), was about €2,302 (CI 95% €1,570–2,830) per patient [€1,524 covered by the NHS (CI 95% €1,214–1,834) and € 778 by the patient (CI 95% €606–960)]. Hospitalization accounted for €916 (CI 95% €670–1,160) per patient per year, followed by rehabilitation €493 (CI 95% €345–641) and diagnostic tests € 387 (CI 95% €314–460).Conclusion: These preliminary results shed some light on the high healthcare services volume and direct healthcare costs from clinic to clinic for visits, unnecessary tests, and prescribed treatments in a real-world overview from a cohort of patients of a specialized clinic in Italy. It may represent a starting point for future studies to statistically test and quantify cost reduction after implementing appropriate healthcare pathways.
Predictive Value of a Combined Model Based on Pre-Treatment and Mid-Treatment MRI-Radiomics for Disease Progression or Death in Locally Advanced Nasopharyngeal Carcinoma
Authors: Kang Le , Niu Yulin , Huang Rui , Lin Stefan (YUJIE) , Tang Qianlong , Chen Ailin , Fan Yixin , Lang Jinyi , Yin Gang , Zhang Peng 
Published: December 2021

PurposeA combined model was established based on the MRI-radiomics of pre- and mid-treatment to assess the risk of disease progression or death in locally advanced nasopharyngeal carcinoma.Materials and MethodsA total of 243 patients were analyzed. We extracted 10,400 radiomics features from the primary nasopharyngeal tumors and largest metastatic lymph nodes on the axial contrast-enhanced T1 weighted and T2 weighted in pre- and mid-treatment MRI, respectively. We used the SMOTE algorithm, center and scale and box-cox, Pearson correlation coefficient, and LASSO regression to construct the pre- and mid-treatment MRI-radiomics prediction model, respectively, and the risk scores named P score and M score were calculated. Finally, univariate and multivariate analyses were used for P score, M score, and clinical data to build the combined model and grouped the patients into two risk levels, namely, high and low.ResultA combined model of pre- and mid-treatment MRI-radiomics successfully categorized patients into high- and low-risk groups. The log-rank test showed that the high- and low-risk groups had good prognostic performance in PFS (P&lt;0.0001, HR: 19.71, 95% CI: 12.77–30.41), which was better than TNM stage (P=0.004, HR:1.913, 95% CI:1.250–2.926), and also had an excellent predictive effect in LRFS, DMFS, and OS.ConclusionRisk grouping of LA-NPC using a combined model of pre- and mid-treatment MRI-radiomics can better predict disease progression or death.
The Development and Validation of the Doctoral Student Identity Scale
Authors: Zhao Jia-lu , Chen Fu , Jia Xiao-ming 
Published: December 2021

Objective:Based on how the identity of doctoral students is recognized and understood in the context of Chinese culture, we developed a doctoral identity scale using both qualitative and quantitative analyses.Methods:The initial project of the Scale was formed through qualitative analyses and expert consultation. Nine hundred and ninety-one doctoral students were officially tested, and 982 valid questionnaires were obtained. They were randomly divided into two parts, and 491 of which were assessed for item Response Theory (IRT) and exploratory factor analysis (EFA) and 491 of which were assessed for confirmatory factor analysis (CFA). The Subjective Well-Being Scale (SWB), the Rosenberg Self-Esteem Scale (RSE), and the Psychological Sense of School Membership Scale (PSSM) were used to test its the criterion-related validity. One hundred and forty-one students were selected for retesting after 8 weeks.Results:The doctoral student identity questionnaire consisted of two factors identity exploration and identity commitment, explaining 57% of the total variance. The results of CFA showed that the two-factor model fitted the data well. The two dimensions of the Doctoral Student Identity Scale were significantly and positively correlated with the two dimensions of the SWB scale (0.32–0.66), the latent factor of the RSE scale (0.42–0.55), and the latent factor of the PSSM scale (0.52–0.62). Composite reliability values for exploration and commitment were 0.79 and 0.83 respectively, and the values of McDonald’s omega for exploration and commitment were 0.81 and 0.85 respectively. The test-retest reliability of the total questionnaire was 0.842.Conclusion:The Doctoral Student Identity Scale was developed with good reliability and validity, and can be used as a reliable tool for measuring the doctoral student identity. In addition, the questionnaire will provide corresponding ideas and methods for studying the identity issues of specific groups.
Location, Clinical Presentation, Diagnostic Algorithm and Open vs. Arthroscopic Surgery of Knee Synovial Haemangioma: A Report of Four Cases and a Literature Review
Authors: Hernández-Hermoso José A. , Moranas-Barrero José , García-Oltra Ester , Collado-Saenz Fernando , López-Marne Sylvia 
Published: December 2021

Objective: The aim was to report 4 patients with intra-articular knee synovial haemangioma (KSH) and to perform a systematic review to describe the patient characteristics, patterns of tumor location, clinical presentation, usefulness of imaging examinations, pros and cons of arthroscopic vs. open resection, and follow-up in the literature.Design: From 1996 to 2016, four patients with KSH were retrospectively reviewed. A literature search was conducted in PubMed from 2000/01 to 2020/06 using the search terms “synovial haemangioma” and “knee.” Fifty full-text articles that included a total of 92 patients were included for further discussion.Results: Four adults (20–40 years) were diagnosed with KSH. Three lesions located in the suprapatellar pouch, two eroding the patella and one the supratrochlear bone, and one in the posterior compartment. Persistent anterior knee pain was the main complain. MRI revealed a benign tumor mass in all cases except one. Open excisional biopsy and regional synovectomy were performed in three patients, and by arthroscopy of the posterior compartment in the fourth. Histological type was arteriovenous in three cases and capillary in one. A pain-free knee without recurrence was achieve in all cases except one, which was successfully reoperated. Average follow-up time was 3.5 years. A literature review showed that KSH appears most frequently in children and teenagers (64.6%) and does not differ by gender. The suprapatellar and patella-femoral joint compartment was the most frequent location (47.9%). The bony tissue of the knee was rarely affected (13.5%). Pain, swelling and haemarthrosis were frequently reported (88.2, 66.7, and 47.1%). MRI was the most commonly used imaging test (98%). Treatment consisted of regional synovectomy by open surgery or arthroscopy in 66.7 and 15.6% of cases, respectively.Conclusions: KSH should be considered in the differential diagnosis of adult patients with chronic low-intensity knee pain. MRI is the most useful exam because it establishes the location, extent and benign characteristics of the tumor. Definitive diagnosis requires histological examination. We believe excisional biopsy and regional synovectomy by arthroscopy should be the treatments of choice for intra-articular tumors, but we recommend open surgery when the lesion extends to the tendons, muscle or bone.
Análisis de modelos de Branding Corporativo
Authors: Limonta Más Rauny Javier , Andraus Quintero César Enrique , Lazo Pastó Orlando Rafael 
Published: December 2021

La marca es uno de los activos intangibles de mayor valor en las empresas. El branding ha estado presente durante siglos, pero el auge de fusiones empresariales a partir de 1980 incrementó el interés en las empresas, dándole importancia al valor de las marcas y a su gestión. Este estudio se centró en hacer una revisión de modelos de branding corporativo propuestos por la literatura, para su clasificación y sistematización. Se realizó una investigación con enfoque cualitativo basada en el método deductivo, a partir de lo general se identificaron los conceptos y modelos de branding corporativo, para luego identificar las variables o elementos que los comprenden. Se pudo apreciar que los modelos analizados son generalmente de construcción de marca con enfoques estratégicos y tácticos, en su mayoría teóricos, es decir, propuestos por autores referentes del marketing mediante investigaciones académicas propias y otras bases conceptuales.

Palabras clave: estrategia de marketing; gestión de marca; branding.

ABSTRACT

The brand is one of the most valuable intangible assets in companies. Branding has been present for centuries, but the rise of corporate mergers since 1980 increased interest in companies giving importance to the value of brands and their management. This study focused on making a review of corporate branding models proposed by the literature, for its classification and systematization. An investigation was carried out with a qualitative approach based on the deductive method, starting from the general, the concepts and models of corporate branding were identified until the variables or elements that comprise these were reviewed. Being able to appreciate that the models analyzed are generally brand building models with strategic and tactical approaches and mostly theoretical, that is, proposed by authors referring marketing through their own academic research and other conceptual bases.

Keywords: marketing strategy; brand management; branding.
Fondements et limites de la notion de mission de service public en matière culturelle
Authors: Benhamou Françoise 
Published: December 2021

The foundation and the limits of the notion of public service in the cultural sector
Many cultural organizations belong to the public sector in France in accordance with the idea of the role of culture for the citizens' education. But the development of a crisis of public financing and of the belief in the superiority of the market led to a reduction of this intervention at the end of the eighties. The analysis of this transformation reveals contradictions and deadlocks that weaken the efficiency of the institutions.
Une rationalisation sans norme organisationnelle : la certification ISO 9000
Authors: Campinos-Dubernet Myriam , Marquette Christian 
Published: December 2021

Una racionalización sin norma organizativa : la certificación ISO 9000
A partir de unas investigaciones empfricas realizadas en seis empresas certificadas desde hace dos anos, el articulo trata de demostrar cómo la certificación ISO 9000 introduce paramètres metodológicos sin normalization organizativa. La diversidad de los modos de utilization de los instrumentos obligados depende estrechamente del contexto organizativo de su inscription. Este ultimo puede traducir una nueva interpretacon del taylorismo, como una racionalización basada en la construction de diferentes saberes de la empresa y el aprovechamiento de la «trazabilidad ». ISO 9000 no puede ser una norma organizativa tanto por sus propios objetivos como por la imposibilidad de poner en normas una dinâmica de aprendizaje.
Structures sociales, traditions culturelles et innovation industrielle dans la Beauce québécoise
Authors: Palard Jacques 
Published: December 2021

Estructuras sociales, tradiciones culturales e innovaciones in-dustriales en la «Beauce» del Quebec.
El anâlisis localizad del conjunto industrial y particularmentente en el medio ambiente rural no puede diferenciarse del anâlisis de las estructuras sociales y de las tradiciones culturales de dicho lugar. El estudio de la «Beauce del Quebec » con pocos factores de desarrollo econômico, merece tal enfoque que privilégia la consideration de los procesos de mobilizaciôn de los recursos, de activaciôn de las técnicas tradicionales, de innovation técnica y organizacional como de colaboracion entre los diferentes grupos de los actores locales (empresarios, electos, instituciones de las finanzas y de la educaciôn...). La fuerte capacidad de los empresarios para adaptarse a las condiciones de la internacionalizaciôn de los intercambios econômicos (especializacion flexible) tiene que ver por parte con la naturaleza de las relaciones sociales que se inician en el seno de las empresas y la importancia de los sentimientos de identidad y de pertenencia.
Sistem Informasi Pengumpulan Data Masyarakat Terkena TBC Untuk Menghindari Terjangkit Covid-19
Authors: Arvita Yulia , Meisak Despita 
Published: December 2021

Banyak masyarakat yang belum mengetahui bahwa mereka terindikasi penyakit TBC di karenakan kurangnya kesadaran akan kesehatan diri sendiri dan juga banyak faktor yang membuat masyarakat enggan untuk berobat, ketika penyakit nya semakin parah dan mengganggu aktifitas barulah mereka memeriksakan diri ke rumah sakit ataupun puskesmas terdekat. Masa pandemi covid-19 adalah masa yang paling berat bagi masyarakat yang menderita penyakit komorbid salah satunya TBC, sehingga masyarakat yang menderita penyakit TBC harus di berikan penanganan serius agar tidak terjangkit virus covid-19. Dengan kemajuan teknologi informasi, penyakit TBC bisa di deteksi sedini mungkin sehingga mempecepat penanganan terhadap masyarakat yang terkena TBC, proses penanganan yang lambat dan tidak tepat akan membuat penyakit semakin parah dan berakibat fatal. Berdasarkan latar belakang di atas, maka solusi yang di hasilkan berdasarkan analisa adalah dengan membuat sebuah Sistem Informasi Pengumpulan Data Masyarakat Terkena TBC Untuk Menghindari Terjangkit Virus Covid-19 dengan Menerapkan Metode Analytical Hierarchy Process. Tujuan di lakukan penelitian ini adalah Dengan adanya sistem informasi yang akan di bangun ini maka pemerintah bisa melihat data masyarakat yang terkena penyakit TBC agar di berikan penanganan yang serius dan juga penyakit TBC bisa dideteksi sedini mungkin agar bisa mempercepat penangan terhadapat masyarakat yang terkena penyakit TBC. Tahapan metode penelitian yang di lakukan yaitu dimulai dari analisis masalah, pengumpulan data, analisa solusi permasalahan, dan desain sistem,
Konstruksi Sosial Masyarakat Namlea atas Pola Hidup Bertoleransi Antara Umat Beragama
Authors: Buton La Husni , Susiati Susiati , Taufik Taufik 
Published: December 2021

Tujuan penelitian ini adalah 1) mengidentifikasi proses konstruksi sosial masyarakat Namlea terhadap pola hidup bertoleransi antara umat beragama dan 2) mengidentifikasi faktor-faktor yang memengaruhi munculnya konstruksi sosial masyarakat Namlea terhadap pola hidup bertoleransi antara umat beragama. Jenis penelitian ini adalah deskriptif kualitatif dengan pendekatan fenomenologis. Data diperoleh dari data primer dan data sekunder. Hasil penelitian menunjukkan bahwa proses konstruksi sosial masyarakat Namlea terhadap cara hidup bertoleransi antarumat beragama berpegang pada teori konstruksi sosial Peter L. Berger, yakni dibagi menjadi dua tahapan, antara lain sosialisasi primer dan sosialisasi sekunder. Pada tahap sosialisasi primer, yang memegang peranan penting dalam memberikan pembelajaran serta menginternalisasikan cara hidup dan sikap bertoleransi antarumat beragama kepada anggota keluarga adalah orang tua yang dituakan dalam rumah tangga. Proses konstruksi sosial secara sekunder melalui pembelajaran di lingkungan masyarakat, baik itu melalui sekolah formal maupun melalui tetua adat, tokoh agama dan lain-lain. Kaitannya dengan sikap dan cara hidup bertoleransi antarumat beragama, maka dalam ketetapan adatpun masyarakat dituntut untuk saling menghargai, menghormati, menerima perbedaan baik itu agama, suku, maupun adat tradisi. Adapun faktor-faktor yang memengaruhi munculnya konstruksi sosial terhadap cara hidup bertolansi antarumat beragama pada masyarakat Namlea, yakni budaya, pendidikan, sosial kemasyarakatan, ekonomi, dan agama.
Od "Theophrastus Redivivus" do Du Maraisa. Źródła laickości w podziemnej filozofii radykalnego Oświecenia we Francji
Authors: Budzanowska Anna 
Published: December 2021

Artykuł przedstawia źródła koncepcji antyreligijnych we francuskiej literaturze filozoficznej radykalnego oświecenia podążając za symbolicznymi, tajnymi manuskryptami m.in: Theophrastus Redivivus, Le Militaire philosophe, Lettre d’Hypocrate à Damagatte, La vie de Mahomed, Le traite sur les trois imposteurs, La Moysade oraz Le Philosophe, by ukazać radykalizm podejścia do religii i wiary mało znanych francuskich libertynów, przedstawicieli tzw. philosophie clandestin: Fontenelle’a, Malebranche’a, Yves de Vallone’a, Delaube’a, R. Challe’a, H. de Boulanvilliers, Du Maraisa.

Okrycia dotyczące francuskich podziemnych manuskryptów filozoficznych budzą zainteresowanie badaczy zmieniając ideowy obraz Oświecenia. Okazuje się bowiem, jak niebagatelny i do tej pory nierozpoznany wkład, wnieśli ci undergroundowi myśliciele, zakresem i radykalizmem swoich koncepcji, w nieodległą epokę encyklopedyzmu i rewolucji 1789. Libertyńskie teorie zrodzone w reakcji na monarchiczny i klerykalny absolutyzm kryją kontekstualną, antysystemową wyrazistość polityczną. Tajni filozofowie traktując religię jako ludzki zamysł służący podporządkowaniu społeczeństwa politycznym partykularyzmom, wywiedli swoje przekonania z poszukiwań zrozumienia całej ludzkiej religijności lub z potrzeb artykułowania uniwersalności religii naturalnej. Nawiązując do podziemnego impulsu antyreligijnego, ich ideowi kontynuatorzy - osiemnastowieczni akademicy i encyklopedyści, nie sformułowali koncepcji przyznania szerokiej tolerancji religijnej lecz wykreowali teorie, które w kolejnym stuleciu stały się historią konfliktu dwóch wizji Francji prowadząc do usunięcie religijności ze sfery publicznej (laïcité).

W artykule opisano formującą się koncepcję laickości w radykalnym, podziemnym ruchu oświeceniowym nawiązując do odłożonych w czasie konsekwencji tego zjawiska, gdy postrzegana jako politycznie niebezpieczna idea ta powróciła do politycznych debat dopiero w drugiej połowie XIX wieku będąc historią konfliktu dwóch wizji państwa, by ostatecznie na mocy ustawy 1905r. stać się la loi fondatrice republikańskiej Francji konstytuując świecką postawę francuskiego społeczeństwa porewolucyjnego i model rozdziału instytucji publicznych od kościołów, w którym państwo nie ingeruje w religię obywatela, a kościoły w funkcjonowanie państwa.
Economic Facts Of Sumatra And Kalimantan Islands For 10 Years
Authors: Piter Nizu Kekry Boy , Fahmi Muhammad 
Published: December 2021

Background: The formulation of this scientific research problem is what are the scientific facts that can be obtained, for 10 years on the island of Sumatra and Kalimantan.
Research purposes: The purpose of this study is identifying scientific facts the direction and pattern of economic growth that occurs on the islands of Sumatra and Kalimantan.
Research methods: The researcher applied quantitative approach, along with descriptive quantitative techniques.
Research results: The results of this research are, there are 2 patterns of economic growth on the islands of Sumatra and Kalimantan during these 10 years. The trend towards growth on these two islands is, has a fluctuating tendency and has indications of a downward trend over the past 10 years. Some special findings are: (1) Aceh Province is quite risky, because over the past 10 years has historical economic growth movements that form the depth of the valley (can be indicated recession), (2) East Kalimantan as many as 4 times over the last 10 years, experiencing negative economic growth, (3) The plantation sector, through CPO exports is able to have its own impact, on the economy of South Kalimantan in 2020. Specifically for economic growth in 2020, it is a special record because of the overall economic growth of 10 provinces on the island of Sumatra and 5 provinces on the island of Kalimantan with negative growth performance.
Conclusion: For Sumatra Island there are 2 different forms of patterns between provinces, pattern 1: Aceh, Riau and Riau Islands. For the case of Aceh province is quite risky because for the past 10 years, it has historical economic growth movements that can indicate recession
Keberlakuan Hukum Dispensasi Nikah pada Masyarakat Kecamatan Seruyan Tengah Kabupaten Seruyan
Authors: Mujiyono Akhmad 
Published: December 2021

Latar belakang: Suatu akad yang melaksanakan ikatan batin yang suci disebut pernikahan. Kehidupan rumah tangga dan ikatan pernikahan di pandang penting dalam agama Islam, hal tersebut dilakukan agar keduanya dapat terjaga dengan baik dan membawa kemaslahatan bagi keduanya.
Tujuan penelitian: Untuk mengetahui problematika yang terjadi keberlakuan pernikahan siri usia di bawah 19 tahun di kecamatan Seruyan Tengah Kab. Seruyan.
Metode penelitian: Penelitian ini menggunakan metode yuridis emperis, dengan pendekatan observasi dan wawancara.
Hasil penelitian: Masyarakat kerap kali melakukan nikah siri ketika ingin menikah di bawah usia 19 tahun pasca di berlakukan hukum dispensasi nikah. Hal ini mereka lakukan di karenakan beberapa faktor yaitu ketidaktahuan, tidak mengerti manfaat pengunaan dispensasi nikah, tidak mengetahui dampak tidak mengunakan dispensasi nikah dan belum adanya sosialisasi. Melihat dari beberapa faktor yang terjadi pada masyarakat kecamatan Seruyan tengah Kabupaten Seruyan di atas maka keberlakuan hukum despensasi nikah tidak berlaku secara efektif.
Kesimpulan: Pernikahan siri yang di lakukan masyarakat Kecamatan Seruyan Tengah Kabupaten Seruyan prespektif keberlakuan hukum despensasi nikah disebabkan ketidaktahuan, tidak mengerti manfaat pengunaan dispensasi nikah, tidak mengetahui dampak tidak mengunakan dispensasi nikah. Pandangan hukum Islam terhadap masyarakat Kecamatan Seruyan Tengah Kabupaten Seruyan yang melakukan nikah siri padahal sudah dispensasi nikah, karena ketidaktahuan aturan perundang-undangan dan tahu aturan tetapi tidak mengerti manfaat dan mudaratnya tidak mengunakan despensasi nikah di karenakan tidak adanya sosialisasi dari instansi yang berkompeten maka pernikahan mereka sah karena adanya Uzur Khafy