bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current trends in education technologies research worldwide: Meta-analysis of studies between 2015-2020
Authors: Yildiz Ezgi Pelin , Cengel Metin , Alkan Ayse 
Published: March 2021

The interaction of education and technology affects the developments occurring in two areas and the development in education increases the speed of technological developments. Educational technology is the functionalization of the scientific knowledge produced in educational sciences and its application into practice. In this research, the content analysis of the studies conducted in Turkey and other countries in the last 5 years is presented in order to determine the current trends in Educational Technology Research Studies. Within the scope of the purposive sample, the studies published between 2015 and 2020 in the field of Educational Technology Research Studies and included in the databases and journals were examined and interpretations were made. Fifteen research criteria were determined within the context of content analysis. These criteria are as follows: index, country, university, department, year of publication, number of authors, research area, method, educational level, sample group, sample number, data collection method, number of bibliographies, analysis techniques and research trends. SPSS 24 program was used in the analysis of the data and the obtained data were presented in the related tables. The data were interpreted based on percentage and frequency. After making general explanations under the tables, the similarities and differences in the studies were analyzed in detail using a meta-analysis method. As a result, it was revealed that the most emphasized issue within the scope of the research area is the adequacy of using Educational Technologies.
Keywords: Educational technology research, current trends, meta-analysis.
Elementary school children’s speech skills in interdisciplinary ICT communication
Authors: Yesnazar Asel , Japbarov Amangeldi , Zhorabekova Ainur , Kabylbekova Zauret , Nuralieva Artyk , Elmira Uaidullakyzy 
Published: March 2021

An analysis of the state of pedagogical practice and scientific and methodological literature speaks of shortcomings in solving the problem of the formation of elementary schoolchildren’s speech skills. This article is devoted to the formation of elementary schoolchildren's speech skills in interdisciplinary communication. The purpose of our experimental work is to verify the effectiveness of our methodology for the sustainable of speech skills in interdisciplinary communication. In preparation for the experimental work, the following objectives were set; to identify the level of formation of speech skills (motivational, informative, reflective), development of a complex of diagnostic methods: observation, questionnaires, diagnostic methods, assessment, self-esteem, etc., on the basis of the data obtained to determine the level of formation of speech skills in interdisciplinary ICT communication. Therefore, the aim of our study is to analyze the state of formation of elementary schoolchildren’s speech skills in interdisciplinary communication. The theoretical significance of the study allows clarifying knowledge on the issue of the formation of speech skills; practical significance lies in the presentation and testing of a set of productive exercises aimed at developing learners' speech skills in interdisciplinary communication. According to the developed diagnostic technique, the formation of speech skills in interdisciplinary communication consists of three components: motivational, substantive and reflective. Based on these components, indicators and levels characterizing the formation of elementary schoolchildren’s speech skills in interdisciplinary communication are distinguished. During the study, the results of a verifying, forming and control experiment were presented. According to the study, we can say that it is necessary to pay attention to the development of meaningful speech, because it is for this indicator that most children are at a low level of formation. On the whole, our study proved that systematic work is needed to form elementary schoolchildren’s speech skills.

Keywords: speech skills, interdisciplinary communication, integration, elementary school, formation, criteria, indicators, levels.
The students’ view for teaching numerical analysis in the form of distance education
Authors: Sarikaya Hediye , Yarimsakalli Mehmet Salih 
Published: March 2021

With COVID-19 pandemic, which was started in Wuhan, Chine, and is still affecting the whole world as well as our country, education offered distantly. This research aims to determine the students' opinions and their behaviors towards teaching Numerical Analysis in the form of distance education. The research was carried out with a group of students studying at the Faculty of Engineering in a private university in Northern Cyprus during the 2019-2020 academic year. In the research, an interview form was applied to get students’ opinions about distance education and to understand whether it is appropriate to give a numerical analysis course over distance education or not. At the end of the research, students’ positive and negative views about distance education emerged. Most of the students argued the idea that distance education platform is not able to provide education as effectively as the traditional classroom environment. It is supported that it is more accurate to give the form of traditional education because of the application of a Numerical Analysis course is challenging.
Keywords: Distance Education, Numerical Analysis, Student, Distance Learning, Information and Communication
Anxiety sensitivity as a transdiagnostic vulnerability factor for cigarette smoking: Clinical and treatment implications
Authors: López-Núñez Carla , González-Roz Alba , Weidberg Sara , Fernández-Artamendi Sergio 
Published: March 2021

Tobacco smoking is the leading preventable cause of premature death worldwide and, despite the fact that many therapies are available for smoking cessation, additional efficacious interventions are needed since many quit attempts are unsuccessful and a high percentage of patients relapse within the months following a quit attempt. In particular, both cigarette consumption and relapse rates among smokers with comorbid mental health problems have shown to be higher than those without them. So far, smoking cessation treatments usually include different approaches aimed at treating specific mental health disorders, particularly anxiety and depression. However, this traditional approach is turning towards a transdiagnostic vulnerability model that includes a set of key clinical factors underlying tobacco use and different emotional conditions, being anxiety sensitivity (AS) increasingly becoming the focus of attention. Preceding research conducted in United States and Argentina has demonstrated that integrating AS reduction components into broader smoking cessation treatments leads to reduced AS levels as well as improved treatment retention and cessation rates. Nonetheless, there are no published behavioral treatment protocols addressing anxiety and smoking concurrently, or using a transdiagnostic approach for this population, in our country. So far, little is known about the mechanisms underlying the relationship between AS and smoking in Spain. Both clinicians and researchers should focus on explore the AS global construct among Spanish smokers, including the most clinically-relevant variables related to both smoking behavior and smoking cessation, with the purpose of developing novel treatment proposals for quitting.
Diagnóstico imagenológico de conductos obliterados: Una revisión.
Authors: Morales-González Francisco Javier 
Published: March 2021

Los exámenes radiográficos son de gran ayuda para que el endodoncista diagnostique y realice planes de tratamiento eficientes en sus pacientes. Hasta hace unos años, las proyecciones en 2 dimensiones, principalmente las radiografías periapicales, eran utilizadas para la planeación de casos endodóncicos de conductos obliterados; sin embargo, en la actualidad, el empleo de la tomografía computarizada de haz cónico (TCHC) es la herramienta más precisa y su uso cada vez es más frecuente, específicamente en casos de obliteración del canal radicular.Aunque todavía no se tienen datos sobre alguna técnica clínica que permita la localización exacta del canal calcificado, se sabe que, en situaciones de endodoncia muy complicadas, el uso intraoperatorio de TCHC puede ayudar al endodoncista a obtener un diagnóstico más adecuado, a garantizar un procedimiento eficaz y, por lo tanto, a conseguir resultados más acertados después del tratamiento. Recientemente, la endodoncia guiada y navegada se ha considerado como procedimiento alternativo al tratamiento convencional que ofrece una solución a los casos de conductos parcial o totalmente obliterados. Debido a que es necesario considerar la preservación de la estructura y la retención a largo plazodel diente después del tratamiento endodóncico, es importante mencionar que las endodoncias guiadas y las navegadas presentan una considerable reducción de lesiones iatrogénicas, como menores complicaciones durante la localización de obliteración en el conducto radicular. Por este motivo, el objetivo de esta revisión fue describir el estado del arte del diagnóstico imagenológico de los conductos obliterados, con las técnicas actuales más novedosas.
Carbonate Caprock–Brine–Carbon Dioxide Interaction: Alteration of Hydromechanical Properties and Implications on Carbon Dioxide Leakage
Authors: Sang Guijie , Liu Shimin 
Published: March 2021

Summary
Caprocks play a crucial role in the geological storage of carbon dioxide (CO2) by preventing its escape and thus trapping it into underlying sequestering reservoirs. An evaluation of interaction-induced alteration of the hydromechanical properties of caprocks is essential to better assess the leaking risk and injection-induced rock instability, thus ensuring a long-term viability of geological CO2 storage. We study the changes in minerals, nanopores, elastic velocities, and mechanical responses of a carbonate caprock caused by rock–water/brine–CO2 interaction (CO2 pressure: ≈12 MPa; 50°C). Before the interaction, the total and accessible porosities are 1.6 and 0.6%, respectively, as characterized by the small-angle neutron scattering (SANS) technique. SANS results show that the total porosity of the carbonate caprock increases, apparently because of rock–brine–CO2 interaction, and the increasing rate rises as brine concentration increases (2.2% for 0 M NaCl, 2.6% for 1 M NaCl, and 2.7% for 4 M NaCl). The increase in total porosity is due to the dissolution of calcite, which tends to enlarge accessible pores (by 0.8 to 1.2%) while slightly decreasing the inaccessible pores (by 0.1–0.2%). Under a CO2–acidified water environment, the compressional-wave (P-wave) and shear-wave (S-wave) velocities (5536.7 and 2699.7 m/s) of a core sample containing natural fractures decrease by 8.5 and 8.1%, respectively, whereas both P- and S-wave velocities (6074.1  and 3858.8 m/s) for an intact sample show only ≈0.5% decreases. The interaction also causes more than 50% degradation of the uniaxial compressive strength for the core sample with natural fractures. X-ray microcomputed tomography experiments on three tiny cores (diameter: 1 mm) after 5-day treatment with CO2 (12 MPa) also show that matrix erosion occurs under CO2–acidified water environment but barely occurs without a direct contact with liquid water. Our study suggests that the hydromechanical properties of carbonate caprocks could evolve over the long-term CO2–brine invasion, and it is critical to monitor the CO2–acidified brine interface for a better and long-term evaluation of the caprock integrity.
Multi-walled Carbon Nanotubes/Manganese Dioxide Nano- flowers-like/Polyaniline Nanowires Nanocomposite Modified Electrode: A New Platform for a Highly Sensitive Electrochemical Impedance DNA Sensor
Authors: Chu Tuan , Tran Luyen Thi , Tran Hoang Vinh , Tran Trung , Nguyen Nghia Trong , Bui Dan , Tran Phu Quang 
Published: March 2021

Abstract
We describe in this report a development of label-free electrochemical DNA sensor based on a novel nanostructured electrode of multi-walled carbon nanotubes (MWCNTs)/ nano-flowers-like manganese dioxide (MnO2)/polyaniline nanowires (PANi NWs) nanocomposite. The nanocomposite was synthesized in-situ onto an interdigitated platinum microelectrode (Pt) using a combination of chemical and electrochemical synthesis methods: chemical preparation of MWCNTs/MnO2 and electropolymerization of PANi NWs. The fabricated MWCNTs/MnO2/PANi NWs was then used to develop a label-free electrochemical DNA sensor for a specific gene of Escherichia coli (E.coli) O157:H7 detection. The MWCNTs/MnO2/PANi NWs modified Pt electrode’s surface can facilitate for probe DNA strands immobilization and, therefore the electrochemical signal of the DNA sensors has been improved. The electrochemical impedance spectroscopy (EIS) measurements were conducted to investigate the output signals generated by the specific binding of probe and target DNA sequences. Obtained results indicated that the developed electrochemical biosensor can detect the target DNA in the linear range of 5 pM to 500 nM with a low limit of detection (LOD) at 4.42 × 10 –13 M. The research results demonstrated that the MWCNTs/MnO2/PANi NWs nanocomposite-based electrochemical DNA sensor has a great potential application to the development of highly sensitive and selective electrochemical DNA sensors to detect pathogenic agents.
Electronic Health Records–Based Cardio-Oncology Registry for Care Gap Identification and Pragmatic Research: Procedure and Observational Study
Authors: Chandra Alvin , Philips Steven T , Pandey Ambarish , Basit Mujeeb , Kannan Vaishnavi , Sara Evan J , Das Sandeep R , Lee Simon J C , Haley Barbara , Willett DuWayne L , Zaha Vlad G 
Published: March 2021

Background
Professional society guidelines are emerging for cardiovascular care in cancer patients. However, it is not yet clear how effectively the cancer survivor population is screened and treated for cardiomyopathy in contemporary clinical practice. As electronic health records (EHRs) are now widely used in clinical practice, we tested the hypothesis that an EHR-based cardio-oncology registry can address these questions.

Objective
The aim of this study was to develop an EHR-based pragmatic cardio-oncology registry and, as proof of principle, to investigate care gaps in the cardiovascular care of cancer patients.

Methods
We generated a programmatically deidentified, real-time EHR-based cardio-oncology registry from all patients in our institutional Cancer Population Registry (N=8275, 2011-2017). We investigated: (1) left ventricular ejection fraction (LVEF) assessment before and after treatment with potentially cardiotoxic agents; and (2) guideline-directed medical therapy (GDMT) for left ventricular dysfunction (LVD), defined as LVEF<50%, and symptomatic heart failure with reduced LVEF (HFrEF), defined as LVEF<50% and Problem List documentation of systolic congestive heart failure or dilated cardiomyopathy.

Results
Rapid development of an EHR-based cardio-oncology registry was feasible. Identification of tests and outcomes was similar using the EHR-based cardio-oncology registry and manual chart abstraction (100% sensitivity and 83% specificity for LVD). LVEF was documented prior to initiation of cancer therapy in 19.8% of patients. Prevalence of postchemotherapy LVD and HFrEF was relatively low (9.4% and 2.5%, respectively). Among patients with postchemotherapy LVD or HFrEF, those referred to cardiology had a significantly higher prescription rate of a GDMT.

Conclusions
EHR data can efficiently populate a real-time, pragmatic cardio-oncology registry as a byproduct of clinical care for health care delivery investigations.
Effectiveness of clinical Pilates and home exercises in sagittal cervical disorientation: randomized controlled study
Authors: Hürer Cemaliye , Angın Ender , Tüzün Emine Handan 
Published: March 2021

Aim:
To compare effects of clinical Pilates and home exercises on postural disorders, strength and endurance of deep cervical flexors (DCF), cervical range of motion (CROM), pain intensity and functional disability in sagittal cervical disorientation.
Patients & methods
: Fourty six patients were included and divided into two groups. Clinical Pilates group performed stabilization based exercise and home exercise group performed conventional exercises.
Results:
Craniovertebral, head tilt, cervicothoracic angles and strength and endurance of DCF muscles had improvement in favor of clinical Pilates group (p < 0.05). There was no difference between groups in terms of right–left acromial distance, pain intensity, functional disability and CROM parameters (p > 0.05).
Conclusion:
Clinical Pilates exercises have been found to provide clinically significant improvements in craniovertebral, head tilt, cervicothoracic angles and strength and endurance of DCF muscles. However, in the increase of CROM, decreasing pain severity and functional impairment parameters there was no superiority of both exercise training.

Clinical trial registration number:
NCT03352921
(Clinicaltrials.gov).
A comparative cost analysis between two quick diagnosis units of different levels of complexity
Authors: Bosch Xavier , Montori Elisabet , Merino-Peñas Maria J , Compta Yaroslau , Ladino Andrea , Ramon Jordi , López-Soto Alfonso 
Published: March 2021

Aim:To compare by micro-costing the costs incurred by quick diagnosis units of tertiary and second-level hospitals.Patients & methods:We included 407 patients from a tertiary and secondary hospital unit. A bottom-up approach was applied.Results:Cost per patient was €577.5 ± 219.6 in the tertiary versus €394.7 ± 92.58 in the secondary unit (p = 0.0559). Mean number of visits and ratio of successive/first visits were significantly higher in the former (3.098 and 2.07 vs 2.123 and 1.12, respectively). Personnel and indirect costs including their percent contribution to overall costs accounted for the main differences.Conclusion:A greater volume of appointments, number of staff and staff time and a greater complexity of patients from the tertiary hospital unit justified the differences in cost outcomes.
Perfil ético del docente universitario desde la valoración de estudiantes de educación
Authors: Ventura Sosa Pedro Emilio 
Published: March 2021

Este estudio, de tipo interpretativo y diseño cualitativo, se propuso comprender, desde la valoración de un grupo de estudiantes de la carrera de Educación, los rasgos que reconocen importantes en el perfil ético de un docente universitario e interpretar las actuaciones que consideran éticas y antiéticas. Fueron sistematizados los registros de opiniones de 39 estudiantes, a través de foros virtuales, un grupo focal y las anotaciones en un registro anecdótico del docente-investigador. El análisis de la información recabada se realizó a partir de categorías emergentes surgidas de los argumentos de los estudiantes. Los resultados destacan como rasgos positivos del perfil ético de un docente universitario: puntualidad, cordialidad, buen trato, coherencia entre el decir y hacer, justicia, solidaridad, democracia y actualización. Los rasgos no deseados incluyeron: responder groseramente, mostrar preferencias, mentir y hacer insinuaciones amorosas. El estudio permitió describir actuaciones éticas de impacto positivo que afianzarían el perfil docente deseable para su formación.
Aspectos históricos del teorema fundamental del cálculo y posibles mediaciones tecnológicas
Authors: Muñoz Villate Weimar 
Published: March 2021

Este artículo presenta aspectos históricos del Teorema Fundamental del Cálculo (TFC) que podrían ser mediados por herramientas tecnológicas. Esta exploración pretende identificar en los argumentos de Newton y de Leibniz, un potencial heurístico para ser incorporados en ambientes de aprendizaje del cálculo en las universidades. Se presentan los resultados de una exploración de actualización de los argumentos de Newton y de Leibniz con la mediación del software matemático Geogebra. Los resultados de esta exploración articulan factores históricos y tecnológicos del TFC, que podrían usarse de manera curricular, por ejemplo, en el diseño de tareas para la formación universitaria.
Trabajo grupal y logro académico en un ambiente virtual de aprendizaje
Authors: Moreno-Salamanca Maria Carolina 
Published: March 2021

El presente artículo contiene los resultados de un estudio de caso, que caracteriza el trabajo de un grupo de estudiantes con logros académicos sobresalientes de la unidad de estudio de geopolítica, correspondiente a un programa de pregrado en modalidad virtual, de una universidad privada localizada en Bogotá, Colombia. El objetivo del estudio fue documentar minuciosamente las formas de trabajo, que permitieran explicar sus altos niveles de desempeño y así establecer los criterios que favorezcan la integración de grupos futuros en ambientes virtuales de aprendizaje. Los criterios de selección del grupo observado fueron los excelentes resultados académicos que obtuvieron y sus altos niveles de motivación frente al grupo. La metodología utilizada fue cualitativa; se realizaron entrevistas individuales semi-estructuradas a cada uno de los integrantes y un grupo focal. Dentro de los principales hallazgos del estudio se encuentran las formas de organización del grupo y las estrategias de trabajo colaborativo.
Meta-analyses of Results From Randomized Outcome Trials Comparing Cardiovascular Effects of SGLT2is and GLP-1RAs in Asian Versus White Patients With and Without Type 2 Diabetes
Authors: Lee Matthew M.Y. , Ghouri Nazim , McGuire Darren K. , Rutter Martin K. , Sattar Naveed 
Published: March 2021

BACKGROUND
Results of cardiovascular outcome trials (CVOTs) suggest Asians may derive greater benefit than Whites from newer classes of antihyperglycemic medications.

PURPOSE
To provide summary hazard ratio (HR) estimates for cardiovascular efficacy of sodium–glucose cotransporter 2 inhibitors (SGLT2is) and glucagon-like peptide 1 receptor agonists (GLP-1RAs) stratified by race (Asian vs. White).

DATA SOURCES
A systematic review performed in PubMed from 1 January 2015 to 8 December 2020.

STUDY SELECTION
Randomized placebo-controlled CVOTs of SGLT2is and GLP-1RAs that reported HRs (95% CIs) for 1) major adverse cardiovascular event (MACE) in patients with diabetes and 2) cardiovascular (CV) death/hospitalization for heart failure (HHF) in patients with HF and reduced ejection fraction (HFrEF).

DATA EXTRACTION AND SYNTHESIS
HRs (95% CIs) for selected outcomes in Asians and Whites were extracted from each trial, adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Random-effects meta-analyses were performed to examine differences between the selected outcomes in Asians versus Whites.

RESULTS
In four SGLT2i trials in type 2 diabetes, the MACE outcome HR (95% CI) in 3,298 Asians versus 20,258 Whites was 0.81 (0.57, 1.04) vs. 0.90 (0.80, 1.00), respectively (Pinteraction = 0.46). In two SGLT2i trials in patients with HFrEF, the CV death/HHF outcome HR in 1,788 Asians versus 5,962 Whites was 0.60 (0.47, 0.74) vs. 0.82 (0.73, 0.92), respectively (Pinteraction = 0.01). In six GLP-1RA trials, the MACE outcome HR in 4,195 Asians versus 37,530 Whites was 0.68 (0.53, 0.84) vs. 0.87 (0.81, 0.94), respectively (Pinteraction = 0.03).

LIMITATIONS
Lack of individual patient–level data, relatively short duration of trial observation, and lack of granular categorization of race within broadly defined Asian subgroups.

CONCLUSIONS
Compared with Whites, Asians may derive greater CV death/HHF benefit from SGLT2is in patients with HFrEF, and MACE benefit from GLP-1RAs in patients with type 2 diabetes.