bluuebunny/crossref_metadata_2025_split huggingface dataset:
70-year anthropogenic uranium imprints of nuclear activities in Baltic Sea sediments
Authors: Lin Mu , Qiao Jixin , Hou Xiaolin , Dellwig Olaf , Steier Peter , Hain Karin , Golser Robin , Zhu Liuchao 
Published: April 2021

Abstract
Strongly stratified water structure and densely populated catchment make the Baltic Sea one of the most polluted seas. Understanding its circulation pattern and time scale is essential to predict the dynamics of hypoxia, eutrophication, and pollutants. Anthropogenic 236U and 233U have been demonstrated as excellent transient tracers in oceanic studies, but unclear input history and inadequate long-term monitoring records limit their application in the Baltic Sea. From two dated Baltic sediment cores, we obtained high-resolution records of anthropogenic uranium imprints originated from three major human nuclear activities throughout the Atomic Era. Using the novel 233U/236U signature, we distinguished and quantified 236U inputs from global fallout (43.3%-50.5%), Chernobyl accident (< 0.9%), and discharges of civil nuclear industry (48.6%-56.7%) to the Baltic Sea. We estimated the total release of 233U (7-15kg) from the atmospheric nuclear weapons testing, and pinpointed 233U peak signal in the mid-to-late 1950s as a potential time marker for the onset of the Anthropocene Epoch. This work also provides fundamental 236U data for Chernobyl accident and early discharges from civil nuclear facilities, prompting worldwide 233U-236U tracer studies. We anticipate our data to be a broader application in model-observation interdisciplinary research on water circulation and pollutant dynamics in the Baltic Sea.
Geno-phenotypic﻿ characteristics﻿ of﻿ Ehlers–Danlos﻿ syndrome:﻿ difficulties﻿ of﻿ disease﻿ type﻿ identification﻿ and﻿ approaches﻿ to﻿ pathogenetic ﻿treatment
Authors: Nikolaeva E. A. , Semyachkina A. N. 
Published: April 2021

Veltischev Researchand Clinical Institutefor Pediatricsofthe Pirogov Russian National Research Medical University, Moscow, Russia The article presents modern data on the most common monogenic connective tissue disease – Ehlers–Danlos syndrome. The authors describe two previous classifications of the syndrome: Berlin (1988) classification, which distinguishes 11 types of the disease, and Beyton (1998) classification, which includes 6 types of the syndrome and takes into account the results of molecular genetic studies. Particular attention is paid to a new classification, proposed by the International Consortium in 2017. This classification is based on the clinical and molecular genetic data and unites 13 types of Ehlers–Danlos syndrome, divided in 7 groups (A–G), depending on the main molecular defect. This defect determines the violation of various collagen structures (primary, spatial, cross-linking) and others constituents of the connective tissue (myomatrix, glycosaminoglycans, complement component, etc.). The classification provides general clinical symptoms for all types of the disease and comprehensive information on the specific signs of each of the 13 types of the syndrome.The authors discuss approaches to the pathogenetic therapy of the syndrome, the possibilities of symptomatic treatment, including both medications of different spectrum of action, and physiotherapeutic measures, exercise therapy. The complex of the listed therapeutic measures is aimed at stabilizing the main pathological process, preventing complications, improving the patient’s quality of life and social adaptation. The authors emphasize that correct patient management, targeted medical supervision and medical genetic counseling requires molecular genetic verification of the diagnosis.
Clinical features of the TORCH syndrome in newborns with congenital cytomegalovirus infection depending on birth body weight
Authors: Kirilochev O. K. , Sergienko D. F. , Kibirova A. I. 
Published: April 2021

Objective: to study the clinical features of TORCH syndrome in newborns with congenital cytomegalovirus infection depending on body weight at birthCharacteristics of children and research methods. The study included 70 patients (43 premature, 27 full-term) with with congenital acute cytomegalovirus infection, manifested form. Patient characteristics: Group 1: 21 premature children with extremely and very low body weight at birth; Group 2: 22 premature children with very low body weight; Group 3: 27 full-term children with body weight more than 2,500 g. The congenital cytomegalovirus infection was diagnosed on the presence of TORCH syndrome and etiological verification in the first 3 weeks of life.Results. The authors found that children with extremely and very low body weight significantly more often (p<0.05) had hydrocephalus and interstitial pneumonia than children with low body weight. The full-term patients weighing more than 2,500 g suffered from hemolytic anemia, brain calcifications and congenital heart defects (p<0.05) statistically significantly more often than preterm patients. Reduced duration of pregnancy in preterm labor contributes to the rare occurrence of hemolytic anemia and calcifications in the brain of premature babies. Periventricular localization of calcifications is characteristic of full-term infants. It is necessary to exclude congenital cytomegalovirus infection in newborns with congenital heart defects and other clinical manifestations of TORCH syndrome.Conclusion. The results of the study can be used to diagnose cytomegalovirus infection in children, depending on the birth weight.
Implementasi Pembelajaran Tematik di Sekolah Dasar Pada Masa Pandemi Covid-19 Ditinjau Dari Teori Konstruktivisme
Authors: Putri Ragil Dian Purnama , Suyadi Suyadi , Siregar Veni Veronica 
Published: April 2021

Abstrak Bahasa IndonesiaPandemi COVID-19 telah merubah tatanan pendidikan di seluruh negara, termasuk Indonesia. Secara tanggap pemerintah telah mengambil sikap bahwa pendidikan harus diterapkan pembelajaran daring untuk mengurangi penambahan kasus COVID-19. Dampak dari kebijakan tersebut terhadap pendidikan antara lain berpengaruh pada kurang maksimalnya pelaksanaan pembelajaran tematik. Artikel ini bertujuan untuk memaparkan implementasi pembelajaran tematik di masa pandemi COVID-19 ditinjau dari teori konstruktivisme di SDN Pilangrejo. Metode penelitian menggunakan penelitian kualitatif jenis survei. Alat pengumpulan data yang digunakan adalah observasi, wawancara, dan dokumentasi. Subjek penelitian ini adalah siswa, guru, dan kepala sekolah. Teknik analisis data yang digunakan adalah kualitatif deskriptif. Hasil penelitian ini menemukan bahwa: 1) kegiatan apersepsi dilaksanakan oleh guru dengan memberikan pertanyaan-pertanyaan kepada siswa, 2) kegiatan eksplorasi dilakukan oleh guru dengan menyampaikan materi melalui Grup WhatsApp dan Youtube, 3) kegiatan diskusi belum maksimal dilaksanakan, dan 4) kegiatan evaluasi dilaksanakan dengan meminta siswa untuk menjawab kuis google formulir. Abstract in englishThe COVID-19 pandemic has changed the order of education in all countries, including Indonesia. The government has responded responsively to the position that education must be applied to online learning to reduce COVID-19 cases. The impact of this policy on education, among others, affects the less than the optimal implementation of thematic learning. This article aims to describe the implementation of thematic learning during the COVID-19 pandemic in terms of constructivism theory at SDN Pilangrejo. The research method used was a qualitative survey type research. Data collection tools used were observation, interviews, and documentation. The subjects of this study were students, teachers, and school principals. The data analysis technique used is descriptive qualitative. The results of this study found that: 1) apperception activities were carried out by the teacher by giving questions to students, 2 the teacher carried out) exploration activities by delivering material through WhatsApp and Youtube Groups, 3) discussion activities were not maximally implemented, and 4) evaluation activities implemented by asking students to answer quiz of Google form.
Mobilitas dan Refleksivitas: Strategi Pemuda Yogyakarta di Masa Transisi menuju Dunia Kerja
Authors: Kuslarassakti Magdalena Putri , Sutopo Oki Rahadianto 
Published: April 2021

This article explains the transition process and youth strategy in Yogyakarta in the era of late modernity. Departing from the context of late modernity in Indonesia, this article applies the concept of mobility as a strategy and reflexive capacity of youth in transition. This article explores the biographical narratives of the four young final-year students in Yogyakarta. By using qualitative methods, this research applies observation techniques and in-depth interviews. The phenomenon of youth studying while preparing for the future, mainly work or/and capital accumulation towards work is a common occurrence of the youth transition in Yogyakarta. Young people respond to the uncertainties of the future and unpredictable consequences of risk through mobility and reflexive capacity as forms of capital. Thus, based on empirical data, those two components become essential and valuable wealth to be accumulated by young people.
Utilization of hydrochar derived from waste paper sludge through hydrothermal liquefaction for the remediation of phenol contaminated industrial wastewater
Authors: Marx Sanette , van der Merwe Karina 
Published: April 2021

Abstract
Hydrothermal liquefaction derived hydrochar produced from industrial paper sludge was used as an adsorbent to remove phenol derivatives from an industrial wastewater stream. Removal efficiency for phenol was determined using synthetic solutions (10–150 ppm) using batch adsorption experiments at a constant solution pH (8), temperature (25 ± 2 °C) and rotary speed (150 rpm). The adsorption of phenol onto hydrochar followed a Freundlich isotherm and could be described with pseudo-second-order kinetic models. Analysis of the adsorption mechanisms showed that particle film mass transport was the rate-determining step in the adsorption process. A COD removal efficiency of 31 ± 1% was achieved for the industrial wastewater stream. All phenol components in the wastewater stream could be removed, but not all organic acids and cyclic ketones. The performance of the paper sludge-based hydrochar compared well with that of activated carbon (44% COD removal). The final phenol concentration in the wastewater stream was below the acceptable phenol concentration for industrial effluents (1 mg/L). The results show that paper sludge can be converted to a valuable marketable commodity that could reduce waste management costs for a paper mill, while also reducing the cost of expensive adsorbents.
ANALISIS KOMPETENSI PROFESIONAL GURU MATEMATIKA BERSERTIFIKAT PENDIDIK PADA MADRASAH IBTIDAIYAH NEGERI (MIN) DI KABUPATEN ACEH BARAT
Authors: Hafriani Hafriani 
Published: April 2021

Sertifikasiguru merupakan proses pemberian sertifikatpendidik kepada guru.Sertifikatpendidikdiberikankepadaguruyang telahmemenuhistandar profesi dan kompetensi guru. Kompetensiguru merupakan seperangkat kemampuanyang harusada dalamdiriguruagardapatmewujudkankinerjanya secaratepat dan efektif. Kompetensi tersebut meliputi kompetensi pedagogik, kepribadian, profesional, dan sosial.Berdasarkan wawancara dengan kepala Dinas Pendidikan Meulaboh diperoleh keterangan bahwa guru kurang aktif dalam kegiatan Kelompok Kerja Guru (KKG) dan dalam berinteraksi dengan orang tua peserta didik. Adanya sertifikasi diharapkan kinerja guru akan menjadi lebih baik. Tujuan penelitian ini adalah untuk mengetahui pengaruh sertifikasi terhadap kinerja guru. MIN di Kabupaten Aceh Barat. Subjekdalampenelitianiniberjumlah14 orang guru dari 7 Madrasah Ibtidaiyah Negeri.Jenis penelitian ini adalah kualitatif dengan metode deskriptif.Teknikpengumpulan data menggunakanLembar observasi kemampuan guru mengajardan angkettertutupdengan skalalikert4, yang dianalisis dengan menggunaan kriteria yang telah ditentukan. Hasil penelitian menunjukkan bahwa kemampuan guru dalam mengelola pembelajaran pada saat dilakukan pembelajaran pada materi dengan model pembelajaran kooperatif berada pada kategori tidak baik hanya satu guru yang berada pada kategori baik yaitu 89,47% dan Respon siswa terhadap penerapan pembelajaran dengan model pembelajaran kooperatif positif. Berdasarkan hasil penelitian tersebut dapat disimpulkan bahwa guru yang sudah mendapat sertifikasi tidak semuanya aktif dan profesional dalam mengelola pembelajaran. Disarankan kepada guru bersertifikat pendidik agar selalu meningkatkan kinerjanya dengan berlandaskan pada kompetensi pedagogik, kepribadian, profesional, dan sosial, sehingga terciptalah keseimbangan antara hak dan kewajibannya.
Thermoregulatory Responses After Uphill Running While Wearing Enforcement Personnel Clothing
Authors: Zahari Norhayaty , Ahmad Mohd Rozi , Raja Azi Raja Mohammed Firhad , Yahaya Ridwan , Che Muhamed Ahmad Munir , Yahya Mohamad Faizul 
Published: April 2021

The choice of clothing for enforcement personnel is vital to ensure minimum physical interference and optimum freedom of movement. The clothing type and fibre composition are important factors that have strong influence on the activities of enforcement personnel. This study presents an evaluation of the thermoregulatory responses for two type of enforcement personnel clothing after uphill running with different material composition. Eight recreational trained respondents (age, 24.4 ± 2.3; height, 166.9 ± 3.3; body weight, 64.0 ± 5.8; BMI 23.0 ± 1.8) completed an 8 km run on a treadmill with 6% elevation wearing enforcement personnel clothing. Both clothing used in the trials were made of polyester/cotton (P50C50) and nylon/cotton (N20C80) material composition. The finding revealed that compared to P50C50 clothing, the N20C80 clothing does not have a good thermal balance. The loss of body mass did not vary significantly but the sweating rate differed significantly between trials (P = 0.008). The Rating of Perceived Exertion (RPE) of the participants was rated higher for N20C80 as compared to P50C50. The thermal sensation (P < 0.001), sweating sensation (P = 0.05), skin wetness (P = 0.007), clothing comfort (P < 0.01) and clothing humidity (P = 0.001) were significantly greater with N20C80 compared to P50C50 during exercise. The P50C50 clothing was more convenient to wear for the uphill running during the exercise. This study suggested that P50C50 would provide a better thermoregulatory response to regulate the thermal equilibrium between human skin and the environment.
Preparation and Characterization of Silica-Coated Iron Oxide Nanoparticles (Fe3O4@SiO2 NPs)
Authors: Taib Nurul Izza , Abdul Latif Famiza , Zambri Nur Diyana Syazwani 
Published: April 2021

In this study, this SiO2 has been coated on the surface of Fe3O4 (Fe3O4@SiO2) by hydrolysis and condensation of tetraethyl orthosilicate (TEOS) under alkaline medium at 80oC. It was found that only 500 mL TEOS is required to obtain the best coated Fe3O4 core structures which has been confirmed from its TEM micrograph. FTIR analyses revealed the formation of Si-O-Si bonds at 1084.2–1101.4 cm-1 hence confirmed that SiO2 has been successfully coated the Fe3O4 core. From the FESEM analyses, the average size of silica was ~ 50 -70 nm. EDX of the Fe3O4@SiO2 showed that silica had been effectively bonded onto the surface of Fe3O4. The VSM measurements confirmed the superparamagnetic properties of Fe3O4@SiO2 that is desirable for biomedical applications.
THE RELATIONSHIP BETWEEN DIETARY ADHERENCE AND GLUCOSE BLOOD IN DIABETES MELLITUS PATIENTS
Authors: Witdiati Khris , Andarmoyo Sulistyo , Purwanti Lina Ema 
Published: April 2021

Diabetes Melitus merupakan penyakit dengan jumlah rawat jalan terbanyak dibandingkan dengan penyakit degeneratif lainnya. Kepatuhan merupakan sesuatu yang paling penting untuk dapat mengembangkan kebiasaan yang dapat membantu penderita Diabetes Melitus dalam menjalankan diet. Hal ini dapat berdampak pada kadar gula darah. Penelitian ini bertujuan untuk menganalisis hubungan kepatuhan diet dengan kadar gula darah pada penderita Diabetes Melitus. Penelitian ini menggunakan desain korelasi untuk mengetahui hubungan antara dua variabel dengan pendekatan cross sectional. Populasi dari penelitian ini adalah seluruh pasien Diabetes Melitus di UGD RSI Siti Aisyah Kota Madiun. Sampel dari penelitian ini adalah sebagian pasien Diabetes Melitus di UGD RSI Siti Aisyah Kota Madiun sejumlah 54 responden. Pengambilan sampel dengan menggunakan teknik purposive sampling. Data dikumpulkan dengan menggunakan kuisioner dan analisis data menggunakan metode Chi Square. Hasil dari penelitian dari kepatuhan diet sebagian besar berada pada kategori kepatuhan rendah (60%). Dan kadar gula darah berada pada kategori kadar gula darah ≥200 mg/dl (26%). Hasil penelitian menunjukkan bahwa ada hubungan yang signifikan antara kepatuhan diet dengan kadar gula darah pasien Diabetes Melitus di UGD RSI Siti Aisyah Kota Madiun. Hasil uji statistik chi square diperoleh p value 0,012 dengan menggunakan taraf signifikasi α = 0,05. Dapat disimpulkan bahwa kepatuhan diet dapat mempengaruhi kadar gula darah pasien Diabetes Melitus. Diharapkan pasien dapat menjalankan diet dengan baik sehingga kadar gula darah terkontrol dan dapat menurunkan risiko komplikasi.
Karakteristik Enkapsulat Teh Instan Daun Kenikir (Cosmos caudatus Kunth.) pada Perlakuan Penambahan Emulsifier Tween 80
Authors: Cahyana Emita Dwi , Wrasiati Luh Putu , Suhendra Lutfi 
Published: April 2021

The aims of research were to know the effect of addition emulsifier tween 80 on the making of Cosmos caudatus Kunth. instant tea, and to determine the addition of the best tween 80 emulsifier to the Cosmos caudatus Kunth. instant tea. This research used a simple randomized block design, wich the concentration of tween 80 as the factor. The concentration of tween 80 used in this research are 0%, 0.5%, 1%, 1.5%, 2%, 2.5%. The data obtained were analyzed by analysis of variance and then processed by the Tukey test. The results showed that the concentration of tween 80 influenced the yield, solubility, total flavonoids, brightness level, redness level, yellowish level, and texture organoleptic tests which included stickiness, dryness and smoothness. The best treatment based on physicochemistry was obtained by adding 1% concentration of tween 80, with a yield value at 11.08 %, solubility at 96.77%, total flavonoids at 9.1041 mg QE/g, the level of brightness (L*) at 36.49, the level of redness (a*) at 19.36, and the level of yellowish (b*) at 30.63. Based on the results of the organoleptic test, respondendts chose treatment without the addition of tween 80, with a stickiness texture value at 4.20 (not sticky),, dryness at 4.60 (dry), and smoothness at 4.75 (smooth).
Keywords : Cosmos caudatus Kunth. leaves, instant tea, encapsulation, tween 80
Diagnostic Labels for Rotator Cuff Disease Can Increase People's Perceived Need for Shoulder Surgery: An Online Randomized Controlled Trial
Authors: Zadro Joshua R. , O'Keeffe Mary , Ferreira Giovanni E. , Haas Romi , Harris Ian A. , Buchbinder Rachelle , Maher Christopher G. 
Published: April 2021

Objective To investigate whether different labels for rotator cuff disease influence people's perceived need for surgery. Design Randomized controlled experiment. Methods Participants with and without shoulder pain read a vignette describing a patient with rotator cuff disease and were randomized to 1 of 6 terms describing rotator cuff disease: subacromial impingement syndrome, rotator cuff tear, bursitis, rotator cuff–related shoulder pain, shoulder sprain, and episode of shoulder pain. Perceived need for shoulder surgery was the primary outcome. Secondary outcomes included perceived need for imaging, an injection, a second opinion, and to see a specialist; perceived seriousness of the condition; recovery expectations; and perceived impact on work attendance. Using a Bonferroni correction (significance, P<.003), adjusted between-group mean differences and 99.67% confidence intervals (CIs) were obtained using a 1-way analysis of covariance. Results One thousand three hundred eight (80% of 1626) responses were analyzed. Participants' mean ± SD age was 40.3 ± 16.0 years, and 59% were women. Mean perceived need for surgery (0–10 scale) was low and slightly higher among those assigned to the rotator cuff tear label compared to the bursitis label (2.6 versus 2.1; adjusted mean difference, 0.7; 99.67% CI: 0.0, 1.4). Mean perceived need for imaging (0–10) was moderate and slightly higher among those assigned to the rotator cuff tear (4.7 versus 3.7; adjusted mean difference, 1.0; 99.67% CI: 0.2, 1.9) and subacromial impingement syndrome labels (4.7 versus 3.7; adjusted mean difference, 1.0; 99.7% CI: 0.1, 1.9) compared to the bursitis label. Conclusion There were small differences in the perceived need for surgery and imaging between some labels, which could be important at the population level. J Orthop Sports Phys Ther 2021;51(8):401–411. Epub 31 Mar 2021. doi:10.2519/jospt.2021.10375
No Added Benefit of 8 Weeks of Shoulder External Rotation Strength Training for Youth Handball Players Over Usual Handball Training Alone: A Randomized Controlled Trial
Authors: Fredriksen Hilde , Cools Ann , Myklebust Grethe 
Published: April 2021

Objective To assess the effectiveness of a short (5–10 minutes) shoulder external rotation (ER) strength program, using elastic bands, in adolescent handball players. Design Randomized controlled trial. Methods The sample included 6 adolescent handball teams (3 female, 3 male) with a total of 92 players and a mean age of 16.6 years. Players were randomized within teams to an intervention group, which completed a shoulder ER strengthening program of 2 exercises performed 3 times per week after handball training for 8 weeks, or a control group of no treatment. The primary outcome was the between-group difference in shoulder ER strength change, measured as isometric strength using a handheld dynamometer from preintervention to postintervention (8 weeks). Secondary outcomes were between-group differences in internal rotation (IR) strength and the ER/IR strength ratio from preintervention to postintervention. Results The estimated between-group difference in dominant-shoulder ER strength was 0.06 N/kg (95% confidence interval [CI]: −0.01, 0.14) in favor of the intervention group. The estimated between-group differences in the ER/IR ratio and IR strength were 0.03 (95% CI: −0.02, 0.08) and 0.02 (95% CI: −0.08, 0.13), respectively. Conclusion The ER strength program improved neither the ER strength nor the ER:IR ratio. J Orthop Sports Phys Ther 2021;51(4):174–187. doi:10.2519/jospt.2021.9957
Masked Graph Modeling for Molecule Generation
Authors: Mahmood Omar , Mansimov Elman , Bonneau Richard , Cho Kyunghyun 
Published: April 2021

De novo, in-silico design of molecules is a challenging problem with applications in drug discovery and material design. We introduce a masked graph model, which learns a distribution over graphs by capturing conditional distributions over unobserved nodes (atoms) and edges (bonds) given observed ones. We train and then sample from our model by iteratively masking and replacing different parts of initialized graphs.We evaluate our approach on the QM9 and ChEMBL datasets using the GuacaMol distribution-learning benchmark. We find that validity, KL-divergence and Fréchet ChemNet Distance scores are anti-correlated with novelty, and that we can trade off between these metrics more effectively than existing models. On distributional metrics, our model outperforms previously proposed graph-based approaches and is competitive with SMILES-based approaches. Finally, we show our model generates molecules with desired values of specified properties while maintaining physiochemical similarity to thetraining distribution.