bluuebunny/crossref_metadata_2025_split huggingface dataset:
Panoramic imaged carotid atheromas are associated with increased neutrophil count: both validated, independent predictors of near-term myocardial infarction
Authors: Chang Tina I , Wu Xiuju , Boström Kristina I , Tran Hoang-Anh , Couto-Souza Paulo Henrique , Friedlander Arthur H 
Published: June 2021

Objectives: Panoramic images (PXs) demonstrating calcified carotid artery atheromas (CCAAs) are associated with heightened risk of near-term myocardial infarction (MI). Elevated neutrophil counts (NC) within normal range 2,500–6,000 per mm3 are likewise associated with future MI signaling the role neutrophils play in the chronic inflammation process underlying coronary artery atherogenesis. We determined if CCAAs on PXs are associated with increased NC. Methods: Investigators implemented a retrospective study of PXs and accompanying medical records of white males ≥ 65 years treated by a VA dental service. Two groups (N = 60 each) were constituted, one with atheromas (CCAA+) and one without (CCAA-). Predictor variable was CCAA + and outcome variable was NC. Bootstrapping analysis determined the difference in mean NCs between two groups, significance set at ≤0.05. Results: The study group of (CCAA+) (mean age 75.9; range 69–91 years) demonstrated a mean NC of 4,843 per mm3 and control group (CCAA-) (mean age 75.3; range; 66–94) a mean NC of 4,108 per mm3. The difference between the groups was significant (p = 0.0008) (95% CI of difference of mean: −432, 431; observed effect size 736). Conclusions: CCAAs on PXs of elderly white males are associated with elevated NC; amplifying need for medical consultation prior to invasive dental procedures.
Case Report: The efficacy of early phacoemulsification in the intraocular pressure control in primary angle closure glaucoma associated with cataract in a young female
Authors: Leferman Carmen-Ecaterina , Cazacut Madalina , Ciubotaru Alin Dumitru 
Published: June 2021

Glaucoma is a leading cause of irreversible blindness worldwide. Among different types of glaucoma, irreversible bilateral visual impairment is more common in primary angle closure glaucoma (PACG) patients. PACG and cataract often coexist and are both more prevalent among the elderly population, being rare in children and young adults. Here, we discuss the case of a 39-year-old Caucasian woman with unilateral PACG associated with cataract. The patient presented with a several-day history of left sided headache, decreased and blurred vision as well as pain and redness of the left eye (LE). She reported similar episodes in the previous year. Visual acuity (VA) of the LE was limited to counting fingers and intra-ocular pressure (IOP) of the LE was 42 mmHg. Anterior segment examination of the LE revealed: edematous cornea, a peripheral anterior chamber depth corresponding to Van Herick’s grade 0, mid-dilated pupil and lens opacities with visible glaukomflecken. Gonioscopic evaluation revealed iridotrabecular contact for 360º, no visible angle structures and a flat–mild convex iris contour. Spectral domain optical coherence tomography suggested only a thinning of neuro-retinal rim at the lower pole. Following treatment of the initial symptoms, phacoemulsification with intra-ocular lens implant was performed. IOP improved and no IOP-lowering medication was required. The patient was monitored for VA, IOP, field of vision changes, and optic disc evaluation every six months for 2 years and no glaucomatous change occurred. The patient also denied ocular symptoms during this period. This case supports the effectiveness of early phacoemulsification in the IOP control in patients with PACG.
Risk factors and experiences of prepartum depression in urban- low-income settlement Nairobi Kenya: a mixed-method study
Authors: Madeghe Beatrice A. , Kogi-Makau Wambui , Ngala Sophia , Kumar Manasi 
Published: June 2021

Background: Prepartum depression is common among pregnant women and has not been studied much in low and middle-income countries. Evidence shows that mental illnesses are prevalent in urban than in rural areas. The study objective was to determine the magnitude of prepartum depression, risk factors, and real-life experiences of depression among pregnant women. Method: A mixed-method cross-sectional study was conducted. It included 262 pregnant women attending antenatal clinics in two public health facilities in urban low-income settlement Nairobi, Kenya. Edinburgh Postnatal Depression Scale (EPDS) with cut-off >13 was used to classify clinical depressive illness. Further, a focus group discussion was conducted with 20 women identified with depression. Univariable analysis with Odd's Ratio was used to test associations. Variables with a p<0.05 in multivariable regression were considered significant. Result: Out of the 262 women, 33.6% were found to have clinical depression as indicated by EPDS score of >13. Women's gestational age was statistically significantly associated with prepartum depression [OR 4.27 (95% C.I. 2.08 - 8.79), p < 0.001]. Income level ≤ 5000 KES was statistically significantly associated with prepartum depression [OR 3.64 (95% C.I.1.25 -10.60), p=0.018]. Further, thematic analysis of qualitative indicated that poverty, lack of social support, domestic violence, and unfriendly health care were major contributors to prepartum depression. Conclusion: Significant numbers of pregnant women were found to experience depression. This prevalence rate indicates a high disease burden of women who live with depression, which is not diagnosed because screening of depression is not done in primary health care centers. This study calls for a need and consideration for screening for perinatal depression in primary health care facilities, mainly in resource-poor areas. Interventions targeting means of resolving conflicts in families are highly needed. Such steps would help achieve key sustainable development goals where maternal and child health remains key priority.
Spatial distribution analysis of dentists, dental technicians, and dental therapists in Indonesia
Authors: Gofur Nanda Rachmad Putra , Aghasy Achmad Zam Zam , Gofur Aisyah Rachmadani Putri 
Published: June 2021

Background: Access to health services is needed around the world, from healthcare providers to doctors. One of the needs in public health is a system that is accessible for everyone, but, unequal distribution of healthcare provider and health workers, especially in dentistry fields is still a main problem in several countries, including Indonesia. The aim of this study is to analyze the spatial distribution of dentists, dental technicians, and dental therapists. Methods: This spatial analysis study was conducted after obtaining secondary data in Indonesia. All data were collected between September 1st, 2020 and October 1st, 2020 from open access sources of de-identified data. The data of dentists per area, dental technicians per area, and dental therapists per area were calculated for analysis. A spatial distribution map was prepared using the Quantum Geographic Information System (QGIS Desktop, version 3.10.6). Results: The results of this study found a ratio of dentists to members of the population in Indonesia of 1:17,105. The average number of dental technicians that work in the public health centers in each province (dental technicians per area) in Indonesia was calculated to be 0.13. The average number of dental therapists that work in the public health centers in each province (dental therapists per area) in Indonesia was calculated to be 0.40. This spatial autocorrelation illustrates that there is a relationship between values of dentists per area and dental therapists per area between provinces in Indonesia, and shows geographic clustering relationships or patterns that are grouped and have similar characteristics in adjacent locations. This spatial autocorrelation did not occur in the value of dental technicians. Conclusions: From this study we can conclude that there is an unequal distribution of dental personnel in Indonesia.
A philosophy of birth: if you want to change the world, change the conversation
Authors: Villarmea Stella 
Published: June 2021

This essay is about why and how we should introduce birth into the canon of subjects explored by philosophy. Birth care brings to the fore fascinating philosophical questions: is a woman in labour a subject with full rights in practice as well as in theory? Can a labouring woman exercise her autonomy in a situation of maximum vulnerability but also maximum lucidity and awareness, as characterises the work of giving birth? What is the relationship between agency, capacity, and pain during and between contractions? Birth care proposes key questions relating to knowledge, freedom, and what it means to be a human being. Nonetheless, giving birth continues to be a blind spot in contemporary prevailing philosophy. My approach to a philosophy of birth aligns with one of the aims of contemporary philosophy; I explore the relationship between knowledge and emancipatory action in the relatively unchartered waters of birth and delivery, to create an epistemology that is sensitive to feminism and embodiment. What I propose to achieve through a philosophy of birth is a new logos for genos —a radically new meditation on origin and birth. How we understand our origin and the practices that bring us into being reveals our humanity. The lived experiences of women and their situated knowledge challenge widely-held assumptions about rationality, about what it is to be a birthing woman and what it is to have agency and capacity in the delivery suite. A philosophy of birth enables us to navigate the stormy waters of contemporary obstetric practice towards a new and radical logos for genos —an embodied genealogy which not only redresses imbalances of gender, but also addresses life and happiness.
Audit of the appropriateness and accuracy of fluid intake and output monitoring: experience in a tertiary hospital
Authors: Lim Siew Hoon , Lim Mei Ling , Aloweni Fazila Abu Bakar , Ang Shin Yuh 
Published: June 2021

Background: The current practice of fluid intake and output monitoring for hospitalised patients in one local acute care tertiary hospital was unclear and inconsistent. Inaccurate fluid balance monitoring and poor documentation can result in poor clinical outcomes. Aim: To provide an overview of the current practice of ordering, monitoring and documentation of patient fluid intake and output during hospitalisation. Methods: Electronic charts of 2199 adults were reviewed for appropriateness and accuracy of monitoring and documentation of the fluid balance records. Data retrieved for each patient included: (1) Was daily fluid balance monitoring clinically indicated? (2) Was daily fluid balance monitoring prescribed by the doctors or initiated by the nurses? (3) Was the daily fluid balance documentation accurate for the entire admission? Findings: Of the reviewed patients, 68% were on fluid balance monitoring, of whom 31% were prescribed by medical teams and 69% were nurse-initiated. Among patients who were receiving fluid balance monitoring, 78% were clinically indicated (35% prescribed by doctors), and 22% had no clinical indications (18% prescribed by doctors). Overall, documentation accuracy of the intake and output charts was 77%, with 100% accuracy in the oral and intravenous fluid intake, and 21% accuracy in the output documentation. Among the inaccurate documentation of monitoring with no quantifiable amount, ‘void in toilet’ was the most inaccurately documented (93.3%). Conclusions: It is vital to address the current disparities in hospital practice, which include prescribing fluid balance monitoring for patients without a clinical indication and documenting incomplete or poor quality information in patients' intake and output charts. Future quality improvement and research work is needed to improve patient safety and outcomes.
COVI-Prim survey: Challenges for Austrian and German general practitioners during initial phase of COVID-19
Authors: Siebenhofer Andrea , Huter Sebastian , Avian Alexander , Mergenthal Karola , Schaffler-Schaden Dagmar , Spary-Kainz Ulrike , Bachler Herbert , Flamm Maria 
Published: June 2021

Background
Coronavirus disease 2019 (COVID-19) represents a significant challenge to health care systems around the world. A well-functioning primary care system is crucial in epidemic situations as it plays an important role in the development of a system-wide response.

Methods
2,187 Austrian and German GPs answered an internet survey on preparedness, testing, staff protection, perception of risk, self-confidence, a decrease in the number of patient contacts, and efforts to control the spread of the virus in the practice during the early phase of the COVID-pandemic (3rd to 30th April).

Results
The completion rate of the questionnaire was high (90.9%). GPs gave low ratings to their preparedness for a pandemic, testing of suspected cases and efforts to protect staff. The provision of information to GPs and the perception of risk were rated as moderate. On the other hand, the participants rated their self-confidence, a decrease in patient contacts and their efforts to control the spread of the disease highly.

Conclusion
Primary care is an important resource for dealing with a pandemic like COVID-19. The workforce is confident and willing to take an active role, but needs to be provided with the appropriate surrounding conditions. This will require that certain conditions are met.

Registration
Trial registration at the German Clinical Trials Register: DRKS00021231.
Direct cost of systemic arterial hypertension and its complications in the circulatory system from the perspective of the Brazilian public health system in 2019
Authors: Curado Daniel da Silva Pereira , Gomes Dalila Fernandes , Silva Thales Brendon Castano , Almeida Paulo Henrique Ribeiro Fernandes , Tavares Noemia Urruth Leão , Areda Camila Alves , da Silva Everton Nunes 
Published: June 2021

IntroductionSystemic arterial hypertension (SAH), a global public health problem and the primary risk factor for cardiovascular diseases, has a significant financial impact on health systems. In Brazil, the prevalence of SAH is 23.7%, which caused 203,000 deaths and 3.9 million DALYs in 2015.ObjectiveTo estimate the cost of SAH and circulatory system diseases attributable to SAH from the perspective of the Brazilian public health system in 2019.MethodsA prevalence-based cost-of-illness was conducted using a top-down approach. The population attributable risk (PAR) was used to estimate the proportion of circulatory system diseases attributable to SAH. The direct medical costs were obtained from official Ministry of Health of Brazil records and literature parameters, including the three levels of care (primary, secondary, and tertiary). Deterministic univariate analyses were also conducted.ResultsThe total cost of SAH and the proportion of circulatory system diseases attributable to SAH was Int$ 581,135,374.73, varying between Int$ 501,553,022.21 and Int$ 776,183,338.06. In terms only of SAH costs at all healthcare levels (Int$ 493,776,445.89), 97.3% were incurred in primary care, especially for antihypertensive drugs provided free of charge by the Brazilian public health system (Int$ 363,888,540.14). Stroke accounted for the highest cost attributable to SAH and the third highest PAR, representing 47% of the total cost of circulatory diseases attributable to SAH. Prevalence was the parameter that most affected sensitivity analyses, accounting for 36% of all the cost variation.ConclusionOur results show that the main Brazilian strategy to combat SAH was implemented in primary care, namely access to free antihypertensive drugs and multiprofessional teams, acting jointly to promote care and prevent and control SAH.
Le frontiere del corpo. Il velo e l’identità femminile nella società multiculturale
Authors: Cagnolati Antonella 
Published: June 2021

La categoria di genere ed il concetto di multiculturalismo possono convivere? Se lo chiedeva già a metà degli anni Novanta Susan Moller Okin, dando origine ad un dibattito che oggi appare di scottante attualità in conseguenza delle polemiche sul velo. In Francia la discussione procede con toni aspri che rivelano la difficoltà di far coincidere teorie libertarie con modelli comportamentali che suscitano ostilità, rancore, diffidenza. Nella realtà la diatriba sul velo nasconde altri significati che rivelano la volontà di marcare con confini precisi l’identità, sia da un parte che dall’altra del confine socio-antropologico. La relazione vuole indagare dietro le prese di posizione per comprendere quali siano i nodi del contendere e per quale motivo le distinzioni e la xenofobia passino ancora una volta sul corpo delle donne, intesi come una trincea per la difesa di valori in opposizione. ¿La categoría de género y el concepto de multiculturalismo pueden vivir uno al lado del otro? se preguntaba a mediados de los años noventa Susan Moller Okin, dando lugar a un debate de gran actualidad como resultado de la controversia sobre el velo. En Francia la discusión se desarrolla con tonos ásperos que revelan la dificultad que existe para conciliar las teorías libertarias con los patrones de conducta que despiertan la hostilidad, el resentimiento, la desconfianza. De hecho, la controversia sobre el velo, esconde otros significados que revelan la voluntad de marcar la identidad con límites claros de un lado y del otro de la frontera socio-antropológica. El artículo tiene como objetivo investigar acerca de las posiciones adoptadas en Europa sobre el velo con el fin de comprender cuáles son los nudos de la controversia y por qué las diferencias y la xenofobia pasan una vez más por el cuerpo de la mujer, entendido como una trinchera para la defensa de valores en oposición.
TEKNIK AUDIO FORENSIK DENGAN METODE MINKOWSKI UNTUK PENGENALAN REKAMAN SUARA PELAKU KEJAHATAN
Authors: Azwar Muhamad , Hidayat Syarif , Yudha Fietyata 
Published: June 2021

Tindak pidana yang dilakukan pelaku kejahatan sedikit tidaknya terdapat barang bukti digital yang ditinggalkan berupa rekaman suara yang dihasilkan dari percakapan menggunakan telepon, algoritma dalam menganalisis suara rekaman banyak beredar di internet salah satunya algoritma KNN yang biasanya digunakan untuk klasifikasi, identifikasi dan prediksi. Penelitian ini menggunakan algoritma tersebut dengan metode Minkowski untuk melakukan pengenalan sampel suara rekaman percakapan pelaku kejahatan dengan sampel suara tersangka. Melibatkan dua responden yang berperan sebagai tersangka dan tiga responden berperan sebagai pelaku. Masing-masing responden akan melakukan dubbing (perekaman suara) dan dipotong menjadi sebelas bagian sebagai data latih dan data uji. sampel suara percakapan akan di extract menggunakan teknik MFCC untuk mendapatkan nilai spectrum yang selanjutnya akan diproses menggunakan algoritma KNN dan metode minkowski menggunakan Python. Hasil dari penelitian ini adalah dari sebelas sampel suara tersangka pertama ada beberapa sampel suara yang Identik dengan sampel suara pelaku dengan tingkat akurasi sebesar 0.63 terlihat dari jarak terkecil yang dihasilkan karena sampel suara pelaku yang mirip dengan sampel suara tersangka pertama diperankan oleh responden yang sama. Sedangkan tingkat akurasi yang didapatkan dari tersangka kedua sebesar 0.18 karena ada dua sampel suara pelaku yang mendekati kemiripan dengan suara tersangka kedua namun diperankan oleh responden yang berbeda, algoritma KNN dengan metode Minkowski dapat digunakan untuk melakukan pengenalan rekaman suara pelaku dengan tersangka karena menghasilkan jarak terkecil yang mendekati kemiripan sehingga barang bukti berupa rekaman suara dapat dipertanggungjawabkan dalam persidangan.
On coupled system of nonlinear Ψ-Hilfer hybrid fractional differential equations
Authors: Mali Ashwini D. , Kucche Kishor D. , Vanterler da Costa Sousa José 
Published: June 2021

Abstract
This paper is dedicated to investigating the existence of solutions to the initial value problem (IVP) for a coupled system of Ψ-Hilfer hybrid fractional differential equations (FDEs) and boundary value problem (BVP) for a coupled system of Ψ-Hilfer hybrid FDEs. Analysis of the current paper depends on the two fixed point theorems involving three operators characterized on Banach algebra. In the view of an application, we provided useful examples to exhibit the effectiveness of our achieved results.
Is there any relationship between LGALS3 gene variations and histopathological criteria in laryngeal squamous cell carcinoma (LSCC)?
Authors: Horozoglu Cem , Demirkol Seyda , Verim Aysegul , Sonmez Dilara , Sürmen Saime , Kucukhuseyin Ozlem , Zeybek Umit , Yaylim Ilhan 
Published: June 2021

Abstract

Objectives
Genetic variations of LGALS3 (Galectin-3) were found to be associated with treatment resistance, mortality, recurrence, high tumor volume and multiple tumor involvement in solid organ cancers. The modulators of extracellular matrix (ECM), which is a dynamic factor in the larynx tissue with high biomechanical and regenerating ability, can play an important role. We aimed to investigate the relationship between the genetic variants of LGALS3, one of these modulators, with Laryngeal Squamous Cell Carcinoma (LSCC).

Methods
LGALS3 gene variations were genotyped by PCR-RFLP method using genomic DNA samples obtained from peripheral blood samples of 74 patients diagnosed with LSCC and 94 healthy controls.

Results
The C allele carriage for the Rs4652 genetic variant was found to be higher (p=0.017) in patients with LSCC. Statistical relationships were found between homozygous genotypes of this variant (CC/AA) with advanced tumor stage (p=0.017) and presence of reflux (p=0.036). CC genotype for rs4644 was found to be higher in cases with positive family history (p=0.036).

Conclusions
Our findings of LGALS3 gene variants, which are also found to be associated with other solid cancers, suggest that they may play a role in LSCC pathophysiology similarly.
Numerical study of hemodynamics after stent implantation during the cardiac cycle
Authors: Belaghit Abdelhakem , Aour B. , Larabi M. , Tadjeddine A. A. , Mebarki S. 
Published: June 2021

The descending aortic aneurysm is one of the most catastrophic cardiovascular emergencies resulting in high mortality worldwide. Clinical observations have pointed out that stent implantation in the sick aorta should probably allow stabilization of the hemodynamic state of the patient's aorta. To better understand the hemodynamic impact of a stent-treated aneurysm, numerical simulations are used to evaluate hemodynamic parameters. These latter including flow profile, velocity distribution, aortic wall pressure and shear stress, which are difficult to measure in vivo. It should be noted that the numerical modeling assists in medical planning by providing patterns of blood circulation, in particular, the distribution of pressures and shear stresses in the wall. In this context, the pulsatile blood flow in the aneurysmal aorta with stent is studied by CFD (Computational Fluid Dynamics) simulations. Realistic boundary conditions time dependent are prescribed at the level of the different arteries of the complete aorta models. The hemodynamic profile of the aneurysmal aorta with stent was analyzed by contour planes of velocity vectors, pressures and shear stresses at different times during the cardiac cycle. The obtained results made it possible to show the effect of the stent on the improvement of the blood flow by solving the problems of hemodynamic disturbances in the aorta. The methodology used in this work has revealed detailed and necessary information for the cases studied and shows the interest of the numerical tool for diagnosis and surgery.