bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultrashort Versus Criterion Heart Rate Variability Among International-Level Girls’ Field Hockey Players
Authors: González-Fimbres Roberto A. , Hernández-Cruz German , Flatt Andrew A. 
Published: March 2021

Purpose: To assess heart rate (HR) variability responses to various markers of training load, quantify associations between HR variability and fitness, and compare responses and associations between 1-minute ultrashort and 5-minute criterion measures among a girls’ field hockey team. Methods: A total of 11 players (16.8 [1.1] y) recorded the logarithm of the root mean square of successive differences (LnRMSSD) daily throughout a 4-week training camp. The weekly mean (LnRMSSDM) and coefficient of variation (LnRMSSDCV) were analyzed. The internal training load (ITL) and external training load (ETL) were acquired with session HR and accelerometry, respectively. Speed, agility, repeated sprint ability, and intermittent fitness were assessed precamp and postcamp. Results: Similar increases in the ultrashort and criterion LnRMSSDM were observed in week 3 versus week 1 (P < .05–.06, effect size [ES] = 0.28 to 0.36). The ultrashort and criterion LnRMSSDCV showed small ES reductions in week 2 (ES = −0.40 to −0.50), moderate reductions in week 3 (ES = −0.61 to −0.72), and small reductions in week 4 (ES = −0.42 to −0.51) versus week 1 (P > .05). Strong agreement was observed between the ultrashort and criterion values (intraclass correlation coefficient = .979). The ITL:ETL ratio peaked in week 1 (P < .05 vs weeks 2–4), displaying a weekly pattern similar to LnRMSSDCV, and inversely similar to LnRMSSDM. Changes in the ultrashort and criterion LnRMSSDCV from week 1 to 4 were associated with ITL (P < .01). The ultrashort and criterion LnRMSSDCV in week 4 were associated (P < .05) with postcamp fitness. Conclusions: The ultrashort HR variability parameters paralleled the criterion responses, and the associations with ITL and fitness were similar in magnitude.
Obstructive spirometry pattern and the risk of chronic kidney disease: analysis from the community-based prospective Ansan-Ansung cohort in Korea
Authors: Kim Sang Hyuk , Kim Hyeon Sam , Min Hyang Ki , Lee Sung Woo 
Published: March 2021

ObjectiveThere have been limited studies on the relationship between obstructive spirometry pattern and the development of chronic kidney disease (CKD). We investigated the association between obstructive spirometry pattern and incident CKD development in a large-scale prospective cohort study.MethodsWe reviewed the data of 7960 non-CKD adults aged 40–69 years who participated in the Ansung-Ansan cohort, a prospective community-based cohort study. Prebronchodilation results for the ratio of forced expiratory volume per 1 s (FEV1) to forced vital capacity (FVC) were used as the primary exposure. The primary outcome was incident CKD, defined as the first event of an estimated glomerular filtration rate <60 mL/min/1.73 m2. HRs and 95% CIs were calculated using multivariate Cox proportional hazard regression analysis.ResultsOver a mean follow-up period of 11.7 years, incident CKD developed in 511 subjects (6.4%). An increase of 0.1 in FEV1/FVC was associated with a decreased risk of incident CKD (HR 0.76, 95% CI 0.68 to 0.84, p<0.001). Compared with the fourth quartile, the HR (95 % CI) of the first quartile of FEV1/FVC ratio was 1.81 (1.39 to 2.36, p<0.001). In the restricted cubic spline curve, the renal hazard associated with a decreased FEV1/FVC ratio was evident at FEV1/FVC values <0.80, showing a U-shaped relationship. In subgroup analysis, the renal hazard associated with a decreased FEV1/FVC ratio was particularly evident in people without metabolic syndrome (p for interaction=0.018).ConclusionDecreased FEV1/FVC ratio was independently associated with an increased risk of incident CKD development, particularly in people without metabolic syndrome. Future studies need to be conducted to confirm these results.
Impacts of the Qingcaosha Reservoir on saltwater intrusion in the Changjiang Estuary
Authors: Ding Zhangliang , Zhu Jianrong , Lyu Hanghang 
Published: March 2021

Abstract
The massive Qingcaosha Reservoir (QCSR) is located in the Changjiang Estuary along the northwest coast of Changxing Island. The reservoir significantly narrowed the upper reaches of the North Channel and deepened the channel near the reservoir. These topographical changes inevitably influenced hydrodynamic processes and saltwater intrusion in the estuary. A well-validated model was employed to investigate the influence of the QCSR on saltwater intrusion in the Changjiang Estuary. The model results showed that the narrowed upper reaches of the North Channel decreased the water diversion ratio and thus increased salinity in the North Channel. During the moderate tide after neap tide, the salinity decreased at the water intake of the QCSR because saltwater intrusion was obstructed at flood slack at the surface, while the salinity increase during the moderate tide after spring tide was mainly due to the intensified saltwater intrusion during spring tide. The deepening of the channel near the QCSR resulted in an increased water diversion ratio, and the salinity in the Eastern Chongming Shoal decreased by more than 0.5 psu during spring tide; however, the saltwater intrusion was enhanced due to the strengthened baroclinic force, which is proportional to the water depth. During neap tide, the salinity in the entire North Channel decreased because of a 1.4% increase in the water diversion ratio of the North Channel and the relatively weak tide.
The study of exotic state $$Z_c^{\pm }(3900)$$ decaying to $$J/\psi \pi ^{\pm }$$ in the pp collisions at $$\sqrt{s}$$ = 1.96, 7, and 13 TeV
Authors: Zhang Zhen , Zheng Liang , Chen Gang , Xu Hong-Ge , Zhou Dai-Mei , Yan Yu-Liang , Sa Ben-Hao 
Published: March 2021

AbstractA dynamically constrained phase-space coalescence model and PACIAE model are used to predict the exotic resonant state $$Z_c^{\pm }(3900)$$

Z
c
±

(
3900
)

yield in pp collisions at $$\sqrt{s} = 1.96, 7$$

s

=
1.96
,
7

and 13 TeV, respectively, which are estimated to be around $$10^{-6}$$

10

-
6

to $$10^{-5}$$

10

-
5

based on the $$J/\psi \pi ^{\pm }$$

J
/
ψ

π
±

bound state in the decay chain of b hadrons. The energy dependence of the transverse momentum distributions and rapidity distributions with $$|y|<6$$

|
y
|
<
6

and $$p_{T}<10$$

p
T

<
10

GeV/c are also calculated for $${Z_c^{+}(3900)}$$

Z
c
+

(
3900
)

and $${Z_c^{-}(3900)}$$

Z
c
-

(
3900
)

. The production of $${Z_c^{+}(3900)}$$

Z
c
+

(
3900
)

and its anti-particle $${Z_c^{-}(3900)}$$

Z
c
-

(
3900
)

are found to be quite similar to each other.
Chapter 1 Introduction and tectonic framework
Authors: Scharf Andreas , Mattern Frank , Al-Wardi Mohammed , Frijia Gianluca , Moraetis Daniel , Pracejus Bernhard , Bauer Wilfried , Callegari Ivan 
Published: March 2021

Abstract

The extraordinary outcrop conditions provide a unique opportunity to study the geology and tectonics of the Oman Mountains, which record a geological history of more than 800 million years. We provide a summary of the geological evolution of the Oman Mountains with the emphasis on the Jabal Akhdar and Saih Hatat domes. This Memoir comprises seven chapters. This first chapter summarizes the former studies and the tectonic framework. This is followed by a comprehensive description of all geological formations/rock units (

Scharf
et al.
2021
a

, Chapter 2, this Memoir) including the famous Semail Ophiolite, the fault and fold pattern (

Scharf
et al.
2021
b

, Chapter 3, this Memoir) and the overall structure (

Scharf
et al.
2021
c

, Chapter 4, this Memoir). Chapter 5 (

Scharf
et al.
2021
d

) explains the varied tectonic evolution of the study area, ranging from the Neoproterozoic until present, while Chapter 6 (

Scharf
et al.
2021
e

) contains the conclusions and a catalogue of open questions. Finally, Chapter 7 (

Scharf
et al.
2021
f

) provides two over-sized geological maps (1 : 250 000 version available online) and a correlation chart, providing an overview of the geological units/formations. This volume is of interest for all geoscientists, geoscience students and professionals studying the Oman Mountains on the surface as well as in the subsurface because it represents a comprehensive and detailed reference.
Chapter 6.1 Marine record of Antarctic volcanism from drill cores
Authors: Di Roberto Alessio , Del Carlo Paola , Pompilio Massimo 
Published: March 2021

Abstract
We review here data and information on Antarctic volcanism resulting from recent tephrostratigraphic investigations on marine cores. Records include deep drill cores recovered during oceanographic expeditions: DSDP, ODP and IODP drill cores recovered during ice-based and land-based international cooperative drilling programmes DVDP 15, MSSTS-1, CIROS-1 and CIROS-2, DVDP 15, CRP-1, CRP-2/2A and CRP-3, ANDRILL-MIS and ANDRILL-SMS, and shallow gravity and piston cores recovered in the Antarctic and sub-Antarctic oceans. We report on the identification of visible volcaniclastic horizons and, in particular, of primary tephra within the marine sequences. Where available, the results of analyses carried out on these products are presented. The volcanic material identified differs in its nature, composition and emplacement mechanisms. It was derived from different sources on the Antarctic continent and was emplaced over a wide time span.
Marine sediments contain a more complete record of the explosive activity from Antarctic volcanoes and are complementary to those obtained by land-based studies. This record provides important information for volcanological reconstructions including approximate intensities and magnitudes of eruptions, and their duration, age and recurrence, as well as their eruptive dynamics. In addition, characterized tephra layers represent an invaluable chronological tool essential in establishing correlations between different archives and in synchronizing climate records.
Boosted microbial productivity during the Toarcian Oceanic Anoxic Event in the Paris Basin, France: new evidence from organic geochemistry and petrographic analysis
Authors: Fonseca Carolina , Mendonça Filho João Graciano , Lézin Carine , Baudin François , de Oliveira António Donizeti , Souza Jaqueline Torres , Duarte Luís V. 
Published: March 2021

Abstract
The Toarcian Oceanic Anoxic Event (T-OAE) is marked by major palaeoenvironmental and palaeoceanographical changes on a global scale, associated with a severe disturbance of the global carbon cycle and organic-rich facies deposition. Here, a multiproxy approach (petrographic and geochemical techniques) was applied to the study of the organic content of the T-OAE of the Paris Basin, whose phytoplanktonic origin has been previously inferred by its geochemical signature.

The top of the
tenuicostatum
Zone is characterized by palynomorphs and marine phytoplankton-derived amorphous organic matter (AOM), representing a proximal marine environment with emplacement of euxinic conditions at the top (total organic carbon/sulfur content and increase in AOM). At the base of the
serpentinum
Zone the proliferation of bacterial biomass begins, with phytoplankton playing a secondary role. This indicates the development of stagnant and restrictive conditions in a proximal environment, with water column stratification (neohop-13(18)-ene). The majority of the
serpentinum
Zone is dominated by bacterial biomass, suggesting a marine environment with bottom-water stagnation, possibly related to basin palaeogeomorphology and circulation patterns, with episodic euxinia.

This therefore suggests that the T-OAE organic fraction is dominated by bacterial biomass, not phytoplankton, showing the importance of an integrated approach to the determination of the organic facies.
Abstract PR-01: Real-time, point-of-care pathology diagnosis via embedded deep learning
Authors: Chen Bowen , Lu Max , Lipkova Jana , Mahmood Faisal 
Published: March 2021

Abstract
There is an urgent need for widespread cancer diagnosis in low resource settings, especially in contrast to areas with developed healthcare systems. According to a study in The Lancet, in the U.S. there is one pathologist for every 20,000 individuals, while in Sub-Saharan Africa, there is only one for every million. In addition, current telepathology systems for cancer diagnosis mostly rely on pathologists performing remotely, which is low-throughput and requires more time and resources. With the growth of telepathology, remote diagnosis becomes a viable solution to address the lack of skilled pathologists in developing regions. Here, we present a cost-efficient device that incorporates embedded deep learning to achieve real time, point-of-care diagnosis of whole pathology slides. We achieve this with a low-cost, 3D-printable microscope that uses the Raspberry Pi and camera module to capture high-resolution images of slides. Then, using a weakly-supervised deep-learning model run on the NVIDIA Jetson Nano, the device is able to accurately classify the whole slide without any pixel-level annotations. Furthermore, the model’s attention-based approach to diagnosis allows us to generate human-interpretable heatmaps displaying the regions most influential to the model’s diagnosis. Our device also incorporates a touch screen and batteries to increase accessibility as an easy-to-use and low maintenance device while still maintaining an efficient runtime given the available resources. Overall, we demonstrate that the device is capable of achieving accurate, high-throughput, and interpretable cancer diagnoses in low resource settings.
Citation Format: Bowen Chen, Max Lu, Jana Lipkova, Faisal Mahmood. Real-time, point-of-care pathology diagnosis via embedded deep learning [abstract]. In: Proceedings of the AACR Virtual Special Conference on Artificial Intelligence, Diagnosis, and Imaging; 2021 Jan 13-14. Philadelphia (PA): AACR; Clin Cancer Res 2021;27(5_Suppl):Abstract nr PR-01.
Optical Coherence Tomography Assessment in Patients Treated With Rotational Atherectomy Versus Modified Balloons
Authors: Hemetsberger Rayyan , Gori Tommaso , Toelg Ralph , Byrne Robert , Allali Abdelhakim , El-Mawardy Mohamed , Rheude Tobias , Weissner Melissa , Sulimov Dmitriy S. , Robinson Derek R. , Richardt Gert , Abdel-Wahab Mohamed 
Published: March 2021

Background:
Percutaneous intervention of calcified coronary lesions often requires lesion preparation with either balloon dilatation or atherectomy. We sought to evaluate the impact of lesion preparation strategy on stent expansion following preparation of severely calcified coronary lesions with modified (cutting/scoring) balloons (MB) versus rotational atherectomy (RA) and to evaluate the impact of calcium burden as assessed by optical coherence tomography (OCT) on acute stent performance.

Methods:
In the PREPARE-CALC trial (Comparison of Strategies to Prepare Severely Calcified Coronary Lesions), 200 patients with severely calcified coronary lesions were randomly assigned to receive either lesion preparation with MB or RA. In 122 patients, OCT was performed before lesion preparation and at the end of the procedure. The principal end point of this OCT sub-analysis was stent expansion as assessed by OCT. The key secondary end points included stent asymmetry and eccentricity.

Results:

The maximal calcific arc (257.5±96.7° versus 248.7±82.1°,
P
=0.59), thickness (1.34±0.29 versus 1.32±0.27 mm,
P
=0.76), and length of calcification (21.1±9.7 versus 24.0±10.9 mm,
P
=0.12) did not differ between the MB versus RA group. Lesion preparation with MB versus RA lead to comparable stent expansion (73.5±13.3% versus 73.1±12.2%, respectively,
P
=0.85). The use of RA did not have a significant impact on stent asymmetry or eccentricity compared with the use of MB. Length of calcified plaque appeared to be increased in patients with stent underexpansion, while thickness of calcified plaque was increased in patients with stent asymmetry. Target lesion revascularization at 9 months was 3.3% when MB was used and 1.6% when RA was performed (
P
=0.62).

Conclusions:
In this OCT sub-analysis from the PREPARE-CALC trial, calcified plaque length was increased in patients with stent underexpansion, while its thickness was higher in patients with stent asymmetry, with no impact of the lesion preparation strategy.

Registration:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT02502851.
Aging Immune System in Acute Ischemic Stroke
Authors: Sykes Gina P. , Kamtchum-Tatuene Joseph , Falcione Sarina , Zehnder Sarah , Munsterman Danielle , Stamova Boryana , Ander Bradley P. , Sharp Frank R. , Jickling Glen 
Published: March 2021

Background and Purpose:
With advancing age, alterations occur to the immune system, including an increase in inflammation (inflammaging) and a reduced ability to respond to new immune challenges. The role of an aging immune system in patients with ischemic stroke remains unclear, although age is an important determinant of stroke risk and outcome. This study assessed the aging immune system in patients with acute ischemic stroke by differences in leukocyte gene expression in relationship to age.

Methods:

Peripheral blood RNA from 2 cohorts with acute ischemic stroke was measured by whole-genome microarray, and genes associated with advancing age were identified (false discovery rate-corrected
P
<0.05, partial correlation coefficient <|0.3|). Genes were characterized by pathway analysis and compared with age-associated genes from nonstroke studies (n=3974).

Results:

There were 166 genes associated with age in cohort 1 (derivation cohort, n=94). Sixty-nine of these age-associated genes were verified in cohort 2 (validation cohort, n=79). Identified genes included a decrease in
CR2
,
CD27
,
CCR7
, and
NT5E
. Genes were associated with altered B-cell receptor signaling, lymphocyte proliferation, and leukocyte homeostasis. Forty-three of the 69 age-associated genes in stroke were also associated with age in nonstroke studies.

Conclusions:
A relationship between leukocyte gene expression and age in patients with ischemic stroke was identified. The changes include alterations to the adaptive humoral immune system, which may influence age-related stroke risk and outcome.
Discovering the Xinyimin in Jakarta: New Chinese Migrants from the prc
Authors: Lin Ping 
Published: March 2021

Abstract
The Belt and Road Initiative (bri) has encouraged many prc nationals to move to Indonesia as (informal) entrepreneurs, firm managers, expatriates, petty traders, migrant laborers, or to accompany family members. It is likely that hundreds of thousands of prc nationals have regularly stayed in Indonesia since between 2000 and 2017. This pilot study found that most new Chinese migrants (xinyimin) were middle- or lower-class people from rural areas in the prc. With limited knowledge and capital, it was difficult for them to achieve a stable and affluent life in the major cities of the prc. However, by moving to Jakarta, their limited assets had greater value because of the development gap between Indonesia and the prc. Most such migrants to Indonesia obtain more promising career opportunities, achieve higher socioeconomic status, and enjoy comfortable lives. Those from coastal prc tend to be managers of large firms; those from the inner regions of the country tend to be petty traders, self-employed, labor migrants, or are hired as local staff. The former are more likely to be conservative with respect to Indonesian society and to align themselves with the prc discourse on the bri; the latter are more responsive to Indonesian society. In general, the fewer resources migrants have in the prc, the more likely they are to settle in Indonesia.
Potential Socioeconomic and Environmental Benefits and Beneficiaries of UAS Atmospheric Profiles from a 3D Mesonet
Authors: Fiebrich Christopher A. , Ziolkowska Jadwiga R. , Chilson Phillip B. , Pillar-Little Elizabeth A. 
Published: March 2021

AbstractIn recent years, technological developments in engineering and meteorology have provided the opportunity to introduce innovative extensions to traditional surface mesonets through the application of uncrewed aircraft systems (UAS). This new approach of measuring vertical profiles of weather variables by means of UAS in the atmospheric boundary layer, in addition to surface stations, has been termed a 3D mesonet. Technological innovations of a potential 3D mesonet have recently been described in the literature. However, a broader question remains about potential socioeconomic and environmental benefits and beneficiaries of this new extension. Given that the concept of a 3D mesonet is a new idea, studies about socioeconomic and environmental advantages of this network (as compared with traditional mesonets) do not appear to exist in the peer-reviewed literature. This paper aims to fill this gap by providing a first perspective on potential benefits and ripple effects of a 3D mesonet, addressing both the added value and prevented losses in specific sectoral applications and for different groups. A better understanding of qualitative economic aspects related to a 3D mesonet can facilitate future developments of this technology for more cost-effective applications and to mitigate environmental challenges in more efficient ways.
A novel missense TGFBI variant p.(Ser591Phe) in a Finnish family with variant lattice corneal dystrophy
Authors: Jaakkola Aino Maaria , Järventausta Petri J , Järvinen Reetta-Stiina , Repo Pauliina , Kivelä Tero T , Turunen Joni A 
Published: March 2021

Introduction: We describe the phenotype of a variant lattice corneal dystrophy (LCD) potentially caused by a novel variant c.1772C>T p.(Ser591Phe) in exon 13 of the transforming growth factor beta-induced (TGFBI) gene. Case report: The proband, a 71-year-old woman referred because of bilateral LCD, first seen at the age of 65 years, with recent progressive symptoms, underwent a clinical ophthalmological examination, anterior segment optical coherence tomography and confocal microscopy. Additionally, three siblings and three children were examined. The identified TGFBI variant was screened in six family members using Sanger sequencing. A corneal dystrophy gene screen was performed for the proband. Translucent subepithelial irregularities and central to midperipheral stubby branching corneal stromal lattice lines, asymmetric between the right and the left eye, were visible and resulted in mild deterioration of vision in one eye. Genetic testing revealed a novel variant c.1772C>T in TGFBI, leading to the amino acid change p.(Ser591Phe). One daughter carried the same variant but had only thick stromal nerve fibres at the age of 49 years. The other family members neither had corneal abnormalities nor carried the variant. No keratoplasty is yet planned for the proband. Conclusions: We classify the novel variant in TGFBI as possibly pathogenic, potentially causing the late-onset, asymmetric variant LCD. Our findings add to the growing number of TGFBI variants associated with a spectrum of phenotypes of variant LCD.