bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pacific Islands Countries Declare Permanent Maritime Baselines, Limits and Boundaries
Authors: Freestone David , Schofield Clive 
Published: November 2021

Abstract
The Pacific Island countries are in the front line of adverse impacts from sea level rise. For the last decade the South Pacific Forum Members have been seeking ways to preserve their entitlements to their maritime zones and resources in the event of inundation of coasts and coastal features as a result of sea level rise. The issue was explored by the International Law Association in its 2018 Report and is being considered by a Study Group of the International Law Commission. This 2021 Declaration by the 18 Members of the South Pacific Forum purporting to fix permanently their maritime entitlements represents a major development in State practice for the region.
Legal Framework for Marine Oil Pollution from Ships in Thailand
Authors: Gamassa Pascal Kany Prud’ome 
Published: November 2021

Abstract
Marine oil pollution from ships has been a constant threat to Thai waters. This article examines the domestication of the provisions of relevant international conventions to which Thailand is a party regarding the prevention, preparedness, response and compensation of claimants of marine oil pollution damage. The current Thai legal framework does not provide for adequate protection of the marine environment. Thailand has not yet become a party to many relevant international conventions and does not provide adequate compensation to victims of marine oil pollution incidents. This article provides recommendations for the improvement of the legal framework of Thailand regarding these issues.
The NHS in Northern Ireland Post-Brexit: the Legal Position on Product Supply
Authors: Yusufi Hafsa , Hervey Tamara , Bloemink Astrid , Cavanagh Annie , Shaw Hannah 
Published: November 2021

Abstract
The UK left the European Union’s single market on 1 January 2021. A Withdrawal Agreement made special provision for Northern Ireland. However, ‘grace periods’ concerning supply of goods were agreed, delaying full application of the new rules. The Northern Ireland NHS is heavily reliant on supplies from Great Britain. If these supplies are disrupted, the quality of care offered to patients will diminish. This article shows the legal details of applicable law once the ‘grace periods’, which are currently securing supply, cease to apply. It reveals significant costs and uncertainties associated with supply of products to the NHS in Northern Ireland. The direction of travel, unless something changes, is that new products will reach patients later than in Great Britain, and there is a real possibility that some products become difficult or impossible for the NHS in Northern Ireland to source. The result will be reduced quality of patient care.
In the Footsteps of Galileo
Authors: de Ceglia Francesco Paolo , Lusito Fabio 
Published: November 2021

Abstract
Italian scientific biopics experienced a period of extraordinary media hype in the 1970s, when some intellectuals personally committed to bringing the lives of the scientists of the past to television in order to discuss the relationship between knowledge and power in the present. Nevertheless, might we properly speak of “Italian-style” historical-scientific fictional drama? To answer this question, we will focus on Roberto Rossellini, Liliana Cavani and, above all, Lucio Lombardo Radice, a promoter, scientific consultant, author and presenter of, and sometimes even actor in, some of the most controversial of these scientific biopics. This article aims, first of all, to reconstruct this history, explaining the reasons for the success of the genre, starting in the 1960s, and the crisis it underwent in the 1980s; secondly, to ascertain the influences these ideological works exerted on choices, approaches and styles of the next generation of science historians and communicators.
Cryptic diversity and gene introgression of Moinidae (Crustacea: Cladocera) in Nigeria
Authors: Deng Zhixiong , Ni Yijun , Wang Jinhui , Ebido Chike Chukwuenyem , Odii Elijah Chibueze , Okoro Joseph Onyekwere , Blair David , Hu Wei , Yin Mingbo 
Published: November 2021

Abstract
The distribution and species/lineage diversity of freshwater invertebrate zooplankton is understudied in Sub-Saharan Africa. In the present study, we explored the lineage diversity and regional distribution of Moinidae (Crustacea: Cladocera) species in Southeast Nigeria. Three species of Moinidae were identified, based on morphology, in 11 of 32 Nigerian lakes examined. Their phylogenetic relationships were investigated based on mitochondrial dna sequences (cytochrome oxidase c subunit I gene; coi) and two nuclear internal transcribed spacer regions (its-1 and its-2). Three coi lineages were detected, corresponding to the morphological species. Two of the coi lineages are newly reported, but one coi lineage (and the haplotype found) is globally distributed, suggesting an ability of moinids to disperse over long distances. Interestingly, two individuals that were morphologically M. cf. macrocopa and had its alleles typical of that species had mtDNA sequences typical of M. cf. micrura. Additionally, one individual that corresponded morphologically to M. cf. macrocopa (and also had a mitochondrial sequence typical of M. cf. micrura) had one its-2 allele typical of that species and one typical of M. cf. micrura. This discordance between mtDNA and nuclear phylogenies suggests gene introgression and/or hybridization between different species within the genus. Our data shows the lineage distribution/diversity and the presence of gene introgression/interspecific hybridization among moinid species from a tropical region.
Histoire concrète de l’abstraction et histoire des mathématiques
Authors: Ehrhardt Caroline 
Published: November 2021

Résumé
Cet article propose de revenir sur le programme d’histoire concrète de l’abstraction proposé par Jean-Claude Perrot dans les années 1990, pour montrer quels en sont les apports pour l’histoire des mathématiques. En mettant l’accent sur les dynamiques sociales, culturelles et matérielles dans lesquelles s’élaborent les connaissances, ce programme fournit en effet des outils pour analyser non seulement les modalités de circulation des mathématiques, mais surtout les effets concrets des pratiques symboliques, souvent laissées de côtés dans les travaux historiens sur les sciences. Plus encore, le programme d’histoire concrète de l’abstraction constitue en objet d’histoire le processus qui permet aux traces matérielles des activités savantes passées et aux modalités de raisonnements qu’elles véhiculent de parvenir jusqu’à nous tout en transcendant leurs conditions initiales de production. Il offre ainsi un cadre analytique pour étudier le rapport des mathématiques au temps historique.
Introduction à la Genèse de l’Histoire (1945)
Authors: Febvre ( - ) Lucien 
Published: November 2021

Résumé
Ces pages dactylographiés ont été conçues par l’historien comme l’introduction d’un livre à écrire. Souvent ainsi, il traçait une ébauche qui tenait lieu ensuite d’introduction. Ici, il indique l’état d’une vaste enquête historiographique tout en récusant à la fois le tropisme historiographique et l’histoire des idées. Son attention au caractère concret des tâches des historiens, en leur temps, ouvre ici une perspective proprement épistémologique. Au passage il se démarque de la notion d’« outillage mental » tel qu’il l’avait employée ailleurs dans les mêmes années.
Comment l’histoire intellectuelle peut-elle servir une réforme de l’histoire économique et sociale ?
Authors: Brian Éric 
Published: November 2021

Résumé
Le projet intellectuel de Jean-Claude Perrot a été formé à l’occasion de la préparation de sa thèse sur la genèse de la ville de Caen. Au cours de cette enquête, il a mesuré les limites de l’histoire économique et sociale qui s’imposait alors comme modèle et les apports d’une histoire des connaissances économiques et sociales contemporaines des phénomènes étudiés. Cette vision d’ensemble a mûri pendant une trentaine d’années pour aboutir d’une part à des propositions neuves relatives à l’histoire intellectuelle et d’autre part à un programme historiographique qui conjuguerait ces deux dimensions. Ce programme a inspiré le « tournant critique » de la revue Les Annales (1989) et il a été exploré par ses continuateurs directs ou indirects. Finalement l’article opère une consolidation conceptuelle selon le principe analysé ailleurs par l’historien.
Modern Judeo-Provençal as Known from Its Sole Textual Testimony: Harcanot et Barcanot (Critical Edition and Linguistic Analysis)
Authors: Nahon Peter 
Published: November 2021

Abstract
This study offers a linguistic description of the idiom of the Jews of the Comtat Venaissin (“Judeo-Provençal”) at the end of the 18th century, based on a critical edition of the only relevant document illustrating this language, a theatrical play in verse entitled Harcanot et Barcanot. The introduction provides a philological inventory of all known sources of “Judeo-Provençal.” The critical and variorum edition of the text, accompanied by linear glosses in English, is followed by a commentary comprising a glossary and analysis of all relevant linguistic features. It reveals, inter alia, that this language possessed words pertaining to the linguistic repertoire of French Jews since the Middle Ages; as for the phonetic features of the Jewish dialect of Provençal, their etiology is to be found in the history of the communities. The study concludes with a reassessment of the nature of linguistic variation in the dialect of the Jews of Provence.
Immunoglobulin Light Chain Amyloidosis Presenting as Inferior Vena Cava Thrombosis
Authors: Axentiev Anna , Rozik Marina , Slama Eliza , Setya Viney 
Published: November 2021

Immunoglobulin light chain (AL) amyloidosis is a rare disease characterized by the deposition of misfolded extracellular proteins within various body tissues resulting in dysfunction of the cardiac, renal, gastrointestinal, hematologic, and nervous systems, among others. Systemic AL amyloidosis often presents with a constellation of vague symptoms such as fatigue, dyspnea, and abdominal pain. Untreated AL amyloidosis with cardiac involvement is rapidly fatal with a median survival of 6 months. In this report, we will highlight the case of a 43-year-old female who presented with generalized abdominal symptoms and fatigue. She was found to have extensive inferior vena cava (IVC) thrombosis extending into the renal veins bilaterally in the setting of nephrotic range proteinuria, new onset arrhythmia, diastolic heart failure, gastrointestinal, and autonomic dysfunction. She received systemic thrombolytic therapy for the IVC and renal vein thrombosis. The multiorgan involvement led us to consider the possibility of amyloidosis. Abdominal fat pad biopsy was performed as part of the diagnostic effort. The abdominal fat pad biopsy did not reveal AL amyloidosis. Ultimately, the diagnosis of systemic AL amyloidosis was made on the basis of pathology from luminal biopsies obtained during outpatient esophagogastroduodenoscopy that was performed days prior to her admission. Unique to our case is the patient presentation with extensive thrombotic disease of the IVC and renal veins. It is important to understand the disease process, presenting signs and symptoms as well as diagnostic essentials based on current literature in order to minimize the morbidity and mortality of this rare disease.
Survival With Surgery Is Superior to Survival Without Surgery in Breast Cancer Patients Aged 85 years or Older: A Retrospective Study
Authors: Enomoto Katsuhisa , Fukumoto Satsuki , Mori Satoshi , Nozaki Fumi , Hara Yukiko , Tada Keiichiro 
Published: November 2021

Background Surgical treatment of breast cancer patients aged 85 years or older is still controversial. Methods A series of surgically treated breast cancer patients aged 85 years or older was evaluated. The clinicopathological features and outcomes of these patients were compared with the features and outcomes of breast cancer patients in the same age group who were managed without surgery. Results A total of 45 patients (75%) received surgical treatment, and 15 patients (25%) were managed without surgery. Significantly more patients treated by surgery underwent systemic treatment than patients managed without surgery ( P = .003). The 5-year disease-free survival rate of patients treated by surgery was 80.7% (95% confidence interval: 66.2–98.5%), which was significantly higher than that of the patients managed without surgery ( P = .001). Conclusions The surgical treatment of breast cancer patients aged 85 years or older is warranted. This outcome was achieved with the use of hormonal therapy.
National trends and cost of litigation in UK National Health Service (NHS): a specialty-specific analysis from the past decade
Authors: Lane Jenni , Bhome Rahul , Somani Bhaskar 
Published: November 2021

Background and aims Medical litigation claim and costs in UK are rising. This study aims to analyse the 10-year trend in litigation costs for individual clinical specialties in the UK from 2009/10 to 2018/19. Methods Data were procured from National Health Service (NHS) Resolution. Number of claims, total litigation costs and cost per claim were ascertained for each financial year. The data collected also includes the number of claims and average amount per claim per speciality during the years 2009–2019 (2009/2010 to 2018/2019 financial years). Results The total annual cost of NHS litigation is currently £3.6 billion(2018/2019). Damages make up the greatest proportion of costs(£1.5 billion). Surgical specialties have the greatest number of claims annually(2847) but Obstetrics has the greatest total litigation(£1.9 billion) and cost per claim(£2.6 million). Number of claims, total costs and cost per claim are significantly greater in 2018/2019 than in 2009/2010. Conclusions Addressing the issue of litigations is complex. Medically there are speciality specific issues that require attention, whilst some general measures are common to all: effective communication, setting realistic targets and maintaining a motivated, adequately staffed workforce. These, alongside legal reforms, may reduce the financial burden of increasing litigation on the NHS.
Sedation and analgesia requirements during venovenous extracorporeal membrane oxygenation in acute respiratory distress syndrome patients
Authors: Ren Xingshu , Ai Yuhang , Zhang Lina , Zhao Chunguang , Li Li , Ma Xinhua 
Published: November 2021

Introduction: The purpose of this study is to describe sedation and analgesia management, and identify the factors associated with increased demand for medication in acute respiratory distress syndrome (ARDS) patients receiving venovenous extracorporeal membrane oxygenation (VV-ECMO). Methods: This retrospective, single-center study included consecutive adult ARDS patients who received VV-ECMO for at least 24 hours from January 2018 to December 2020 in a comprehensive intensive care unit. The electronic medical records were retrospectively reviewed to collect data. Results: Forty-two adult patients meeting the inclusion criteria were included in the study. Midazolam, sufentanil, and remifentanil were main sedatives and analgesics used in the patient population. The morphine equivalents, representative of the demand for opioids, was 512.9 (IQR, 294.5, 798.2) mg/day. The midazolam equivalents, representative of benzodiazepine requirement, was 279.6 (IQR, 208.8, 384.5) mg/day. The levels of serum creatinine, total bilirubin, lactic acid, SOFA score, and APACHE Ⅱ score at cannulation were found to be associated with opiate or benzodiazepine requirements. Multiple linear regression analysis revealed a linear correlation between midazolam equivalents and morphine equivalents (p < 0.001). In addition, there was a negative linear correlation between Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE Ⅱ) score and midazolam equivalents (p = 0.024). Conclusions: The sedation and analgesia requirements of ARDS patients receiving VV-ECMO often increase simultaneously. More large-scale studies are needed to confirm the risk factors for increased sedation and analgesia needs in patients supported on VV-ECMO.
Prospective memory deficits following acute alcohol consumption
Authors: Elliott Morgan , Terrett Gill , Curran H Valerie , De Bono Natalie , Rendell Peter G , Henry Julie D 
Published: November 2021

Background: Prospective memory is a critical neurocognitive capacity that refers to the ability to execute delayed intentions. To date, few studies have investigated the effects of acute alcohol consumption on prospective memory, and important questions remain about the mechanisms that might underpin acute alcohol-induced prospective memory impairment. Aims: The current study sought to clarify the nature and magnitude of prospective memory difficulties following acute alcohol consumption and to test the degree to which any problems with prospective remembering might be a secondary consequence of broader cognitive impairment. This study also investigated whether there were potential sex differences. Methods: In all, 124 healthy adult social drinkers were assigned to either the alcohol ( n = 61) or placebo ( n = 63) condition. Participants were administered a dose of 0.6 g/kg alcohol or a matched placebo drink and then asked to complete a measure of prospective memory. A broader neurocognitive test battery was also administered. Results: Relative to the placebo condition, acute alcohol intoxication led to significant impairment on all prospective memory tasks, with effects mostly large in magnitude. These difficulties could not be explained by broader problems in retrospective memory, executive function or episodic future thinking. In addition, females recorded a higher blood alcohol concentration than males; however, no sex differences in prospective memory performance were identified following acute alcohol use. Conclusion: The results show that acutely, even a moderate dose of alcohol substantially impairs prospective memory function. These findings have potentially important implications for understanding many of the maladaptive behaviours associated with acute alcohol consumption.
Warmed contrast media temperature loss in traditional manifold systems during angiographic procedures
Authors: O'Sullivan Kevin J. , Kermavnar Tjaša , Gorski Kenneth A. , Arnous Samer , O'Sullivan Leonard W. 
Published: November 2021

Background Extrinsic warming of contrast media (CM) to 37 °C before angiographic procedures is performed to improve bolus kinetics and avoid potential adverse effects. Extrinsically warmed CM readily loses temperature after removal from the warming cabinet, but the extent of its cooling has not been previously investigated. Purpose To assess temperature loss of extrinsically warmed CM in tubing of traditional angiographic manifolds during simulated angiography. Material and Methods In total, 35 scheduled diagnostic angiographic procedures were observed in a hospital setting. Relevant time points of CM use during the procedures were recorded. The shortest, median, and longest procedures were then simulated in the experimental laboratory to measure CM temperatures at specific times at three locations along the tubing system. Results The angiographic procedures lasted 7.0–26.6 min (median = 11.7 min), with the total duration dependent primarily on the time from contrast being removed from the warming cabinet to the commencement of imaging. During the simulated procedures, consistent patterns of temperature loss were observed. By the last simulated angiographic run, injected CM temperature decreased by 7.4–16.4 °C, depending on procedure length. Most of the heat loss occurred in the tubing between the CM bottle and coronary control syringe. Conclusion During angiographic procedures, prewarmed CM loses its temperature rapidly with the duration of exposure to ambient room temperature. If no additional measures are employed to maintain its temperature outside of the warming cabinet, extrinsic warming has limited impact on injected CM temperature.
Mothers Caring for Adult Children With Substance Use Disorder: Understanding Lived Experience
Authors: St-Amant Oona , Schwind Jasna K. 
Published: November 2021

Background Most persons with substance use disorder (SUD) live in family settings. In the absence of adequate mental health services, mothers are often called upon to provide care for their adult children with SUD. Despite positive outcomes such as decreased rates of hospitalization associated with family involvement, mothers are often stigmatized within the health care systems as contributors to trauma and/or family dysfunction. Purpose The purpose of this study is to explore mothers’ lived experience of caring for adult children with SUD. Method Guided by critical feminist theory, this study used interpretive descriptive qualitative research design to identify patterns within mothers’ experiences for practical relevance and application to service provision. Results The findings yielded in this study identified mothers’ experiences as: longing for wellness, identity as loving mother, loss, anticipatory grief, shame and blame and feeling excluded from services. Ultimately, the findings from this study extend the limited research to date on mothers’ experiences of stigma, especially when they are blamed for their child’s illness. Conclusions Findings from this study advocate for family-centered approaches that attend to mothers’ unique experience, from their standpoint, and offer recommendations for change to service provision.
The Potential Win-win Strategy for Healthy Aging and Environmental Protection: Environmental Volunteering
Authors: Hung Chung-Shan , Loh Ching-Hui , Hsieh Jyh-Gang , Chen Jia-Ching , Lin Yan-Wei , Yen Chia-Feng 
Published: November 2021

Purpose To explore the physical activity level of community environmental volunteering (CEV) participants and the differences in physical functions and daily activity patterns between the older adults who engaged in intensive CEV (≥15 hours/week) and non-intensive CEV (<15 hours/week) groups. Design Cross-sectional study. Setting Three recycling stations in Taiwan. Sample In total, 113 community-dwelling older adults who regularly participated in CEV. The response rate was 53%. Measures The ActiGraph wGT3x-BT accelerometer for the percentage of sedentary, light, and moderate to vigorous physical activity (MVPA) of CEV time and awaken time; the Jamar hand dynamometer for grip strength; and the MicroFET3 muscle testing dynamometer for knee extension strength. Analysis Analysis of covariance with the baseline characteristics as covariates. Results Overall, MVPA, light, and sedentary activities accounted for 53.73%, 41.10%, and 5.23% of CEV time, respectively. The intensive group (n = 61) displayed greater dominant handgrip strength ( P = .004) and higher MVPA percentage in daily life ( P = .044) than the non-intensive group (n = 52). Conclusion CEV provides sufficient opportunities for older adults to perform physical activity. Intensive CEV is related to greater handgrip strength but not lower limb strength. Further study is needed to establish the causal relationship between CEV and health variates.