bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGOLAHAN LIMBAH DOMESTIK RUMAH MAKAN DENGAN MOVING BED BIOFILM REACTOR (MBBR)
Authors: Dickdoyo Aditya Titian , Cahyonugroho Okik Hendriyanto 
Published: August 2021

Saat ini usaha rumah makan jumlahnya semakin meningkat. Air buangan yang diakibatkan oleh aktivitas rumah makan tersebut akan menjadi suatu permasalahan bagi lingkungan. Pengolahan air buangan rumah makan bisa dilakukan dengan cara pengolahan biologis karena dapat menurunkan kandungan organik pada air limbah. Proses pengolahan biologis yang dapat digunakan yaitu dengan sistem Moving Bed Biofilm Reactor (MBBR). Proses MBBR pada prinsipnya adalah pertumbuhan biologis dengan menggunakan biakan tersuspensi dan melekat yang tercampur didalam suatu reaktor dengan aerasi dan media yang bergerak. Penelitian ini bertujuan untuk mengetahui kinerja MBBR dalam menurunkan TOC dan TSS pada air buangan rumah makan. Media yang digunakan adalah Kaldness K3 dan Bioball dengan variasi komposisi media yaitu 100% Kaldness K3, 100% Bioball, 50% Kaldness K3 dan 50% Bioball, 60% Kaldness K3 dan 40% Biobll, 40% Kaldness K3 dan 60% Bioball. Variasi kedua adalah waktu sampling yaitu 3 jam, 6 jam, 9 jam, 12 jam, dan 15 jam. Berdasarkan hasil penelitian ini menunjukkan bahwa kemampuan reaktor MBBR paling optimum adalah dengan komposisi 100% Kaldness K3 pada waktu sampling 15 jam. Reaktor tersebut dapat menurunkan TOC sebesar 97,84% dan untuk penurunan TSS sebesar 76,84%
UPAYA PENINGKATAN CITRA KAWASAN WISATA BUDAYA PADA SANGGRALOKA SEKAR WILIS PONOROGO
Authors: Elviana Eva , Winarto Erwin Djuni , Avenzoar Azkia 
Published: August 2021

Sanggraloka Sekar Wilis merupakan nama sebuah kawasan wisata yang terletak di desa Kesugihan Kecamatan Pulung, Ponorogo. Dengan lokasi tapak di lereng gunung Wilis, dilatar belakangi perbukitan, memberikan panorama alam yang indah, didukung dengan berbagai macam pepohohan sebagai peneduh serta adanya sumber air bersih yang dimanfaatkan menjadi sebuah kolam renang keluarga. Adanya beberapa fasilitas bermain anak, serta bumi perkemahan, menjadikan tempat ini banyak dikunjungi oleh masyarakat sekitar. Meski terdapat bangunan Pendopo dengan style Joglo Panoragan pada kawasan ini, namun citra kawasan yang mencerminkan seni budaya Ponorogo, belum tesedia secara memadai. Atraksi budaya seperti pagelaran tari Reog Ponorogo, dilakukan pada ruang terbuka yang masih cukup luas. Penelitian ini bertujuan untuk melakukan upaya meningkatkan citra kawasan sebagai wisata budaya, melalui eksplorasi elemen-elemen arsitektur sehingga mampu meningkatkan citra kawasan dengan mengangkat nilai-nilai tradisi-kelokalan (vernacular). Penelitian kualitatif ini menggunakan metode analisis secara diskriptif melalui observasi lapangan dan indepth interview. Hasil penelitian menunjukkan bahwa penggunaan arsitektur vernacular pada penyelesaian bangunannya, dapat peningkatan citra kawasan wisata, sehingga memperkuat identitas budaya Ponorogo.
PENGARUH ADSORBEN KOMERSIAL TERHADAP PENURUNAN FOSFAT DAN SURFAKTAN ANIONIK (DETERGEN) PADA AIR LIMBAH LAUNDRY
Authors: Damayanti Lila Kurnia , Hidayah Euis Nurul 
Published: August 2021

Peningkatan aktivitas laundry di perkotaan Surabaya menimbulkan peningkatan penggunaan deterjen ,dimana kandungan dalam deterjen memiliki pengaruh buruk terhadap lingkungan .Penelitian ini menggunakan metode adsorpsi dengan karbon aktif komersial aliran upflow dengan Variasi debit 5 ml/menit, 10 ml/menit,dan 15 ml/menit dengan variasi tinggi 10 cm,15 cm, dan 20 cm serta waktu sampling 2 jam,4 jam, 6 jam, 8 jam, 10 jam dan 12 jam . Hasil yang diperoleh efisiensi tertinggi dari penyisihan fosfat sebesar 99,07 % dan surfaktan anionic (detergen) 95,35 %. Debit optimum adalah 5 ml/menit dengan ketinggian 15 cm fosfat dan 20 cm surfaktan anionic (detergen).Model yang sesuai adalah freunlidch, dimana nilai R2 0,9418.
PEMODELAN KEBISINGAN LALU LINTAS BERDASARKAN VOLUME LALU LINTAS MENGGUNAKAN MULTIPLE LINEAR REGRESSION PADA JALAN KEDUNG COWEK SURABAYA
Authors: Almadhany Muhammad , Rosariawari Firra 
Published: August 2021

Jalan Kedung Cowek merupakan jalan arteri primer yang melayani skala nasional, sehingga mempunyai volume lalu lintas tinggi yang menyebabkan kebisingan lalu lintas. Maka perlu adanya model kebisingan lalu lintas yang dapat memprediksi kebisingan lalu lintas untuk memudahkan dalam upaya pengontrolan kebisingan lalu lintas. Penelitian ini bertujuan untuk memperoleh model kebisingan lalu lintas berdasarkan volume lalu lintas setiap jenis kendaraan. Metode yang dilakukan dalam penelitian adalah dengan survei langsung di Jalan Kedung Cowek untuk memperoleh data tingkat kebisingan dan volume lalu lintas. Analisis data untuk memperoleh pemodelan kebisingan lalu lintas menggunakan Multiple Linear Regression dengan bantuan software Minitab versi 19. Model kebisingan lalu lintas pada Jalan Kedung Cowek yang diperoleh yaitu LEQ = 71,292 + 0,001811 MC + 0,00487 LV – 0,0078 HV dengan nilai koefisien determinasi (R2) sebesar 0,5940. Model tersebut masih belum terlalu baik, karena banyaknya kendaraan yang memakai knalpot tidak standar yang menyebabkan tingkat kebisingan menjadi lebih tinggi.
PENGOLAHAN LINDI (LEACHATE) MENGGUNAKAN MOVING BED BIOFILM REACTOR (MBBR) DENGAN PROSES OXIC-ANOXIC
Authors: Rozika Dwi Iswatul , Purnomo Yayok Suryo 
Published: August 2021

Lindi (leachate) merupakan salah satu limbah yang berbahaya apabila dibuang langsung ke badan air dan tidak dilakukan pengolahan terlebih dahulu. Pengolahan biologis, seperti Moving Bed Biofilm Reactor (MBBR). MBBR merupakan pengolahan yang menggunakan media sebagai tempat melekatnya mikroorganisme. Penelitian ini bertujuan untuk mengetahui kemampuan reaktor MBBR dengan menggunakan proses oxic-anoxic dalam menurunkan parameter COD, BOD, NH3-N. Variasi yang digunakan pada penelitian ini ada tiga yaitu, variasi media, volume media, dan waktu tinggal. Media yang digunakan pada penelitian ini adalah kaldnes K5 dan spons (biocube) dengan volume 25%, 35%, dan 45%. Waktu tinggal yang digunakan pada penelitian ini yaitu 6 jam (oxic 4 jam – anoxic 2 jam), 8 jam (oxic 5 jam – anoxic 3 jam), 11 jam (oxic 7 jam – anoxic 4 jam), 17 jam (oxic 10 jam – anoxic 7 jam), dan 33 jam (oxic 20 jam – anoxic 13 jam). Hasil yang paling optimum pada waktu tinggal 33 jam (oxic 20 jam – anoxic 13 jam) menggunakan media spons (biocube) dengan volume 45% dengan hasil yang didapat untuk COD sebesar 85%, BOD sebesar 90%, dan NH3-N sebesar 84%.
HUBUNGAN ANTARA OBESITAS DENGAN KEJADIAN OSTEOARTHRITIS SENDI LUTUTDI RSU TEUNGKU PEUKAN ACEH BARAT DAYA
Authors: Sofyan Zur Rahmi , Rizal Fakhrul 
Published: August 2021

Osteoarthritis (OA) atau penyakit sendi degeneratif yang progresif bersifat kronik dan biasanya terjadi pada usia pertengahan hingga usia lanjut ditandai dengan adanya kerusakan kartilago sendi. Osteoartritis memiliki faktor risiko yang dapat dimodifikasi yaitu obesitas, seseorang dengan obesitas atau overweight tiga kali berisikoterkena OA lutut. Obesitas yaitu BMI/IMT mulai dari 30 hingga >40 kg/m2. Penelitian ini bertujuan untuk mengetahui Hubungan antara Obesitas dengan kejadian Osteoartritis Sendi Lutut di RSUD Teungku Peukan Aceh Barat Daya. Jenis penelitian ini adalah metode penelitian kuantitatif dengan desain pendekatan studi cross sectional. Populasi pada penelitian ini adalah seluruh pasien OA lutut dengan Obesitas. Sampel pada penelitian ini berjumlah 70 orang yang diambil memenuhi kriteria inklusi dan kriteria eksklusi dengan teknik Non Probability sampling. Pengambilan data dengan menggunakan kuesioner, wawancara serta mengukur berat badan dan tinggi badan. Analisis data menggunakan uji chi-square pada tingkat kemaknaan 95% (P<0,05). Hasil uji statistik pada penelitian ini dengan menggunakan uji chi square test didapatkan P value = 0,000 (P < 0,05) yang berarti terdapat hubungan yang bermakna antara obesitas dengan kejadian Osteoartritis (OA) lutut pada poli Bedah, poli Saraf dan poli Penyakit Dalam di RSUD Teungku Peukan Aceh Barat Daya.
Rancang Bangun Aplikasi Pengenalan Rukun Islam Sebagai Media Pembelajaran Menggunakan Teknologi Augmented Reality
Authors: Mulyani Asri , Kurniadi Dede , Akbar Musadad Mahendra 
Published: August 2021

Poin utama dari ajaran islam adalah rukun islam dan juga merupakan pendoman seorang muslim seperti mengucapkan syahadat, sholat, zakat, puasa, dan naik haji. Pembelajaran mengenai rukun islam disekolah sering kali disampaikan melalui buku yang terkadang membuat menimbulkan efek bosan untuk menambah minat belajar pada anak disaat kegiatan pembelajaran tidak perbolehkan melakukan tatap muka dikarenakan situasi pandemi covid-19, maka dari itu pembelajaran tersebut dikemas lebih menarik dengan memasukan unsur multimedia. Penelitian ini bertujuan untuk membuat aplikasi pengenalan rukun islam menggunakan augmented reality yang menjadi variasi. manfaat dari penelitian ini yaitu dapat dijadikan media pembelajaran yang menarik minat anak dalam mempelajari rukun islam khususnya bacaan dan gerakan sholat dan sebagai alat bantu untuk pengajar dalam menyampaikan pembelajaran tentang rukun islam. Pembuatan aplikasi ini menggunakan metodologi Research And Development dengan tahapan analisis, pengumpulan data, perancangan desain, implementasi desain, pengujian, validasi ahli, revisi, uji kelayakan, perbaikan media dan produk.Hasil dari penelitian ini berupa aplikasi pengenalan rukun islam sebagai media pembelajaran mengguanakan augmented reality dengan platform androidI untuk mengoprasikannya.
Correlation between Age and Body Mass Index (BMI) with Histopathological Features of Breast Cancer Patients in RSUP Haji Adam Malik Medan
Authors: Mardiah Harisa , Ginting Radita Nur Anggaeni , Rahmadhany Heru , Sitorus Esther Reny Deswani 
Published: August 2021

Background: Breast cancer is influenced by various risk factors, including age and obesity. Older women who are overweighted and obese have a higher risk of developing breast cancer. This study aims to find the correlation between age and body mass index (BMI) with histopathological features of breast cancer patients in RSUP Haji Adam Malik Medan.Methods: This research is an analytical study using a cross-sectional design with 103 samples obtained from medical record data by random sampling. The data obtained were then adjusted to the research criteria and grouped based on predetermined variables.Results: The majority of the age group was 41-50 years (36.9%), obesity BMI (40.8%), histopathological subtype of invasive carcinoma of no special type (NST) (85.4%), and grade II (46.6%). Kruskal-Wallis test result between histopathological subtypes and breast cancer grading based on age, respectively, obtained p=0.503, r=.325; (α>0.05), and p=0.207, r=0.393; (α>0.05), while based on BMI obtained p=0.017, r=0.021; (α<0.05), and p=0.018, r=0.018; (α<0.05). The OR value (95% CI) obtained on overweight-obese BMI with invasive carcinoma NST subtype was 7.63 (7.27–14.90) and other subtypes were 2.40 (1.14–13.75), and for grades II and III, they were respectively 3.57 (1.32–8.09) and 3.27 (1.17–9.91).Conclusions: There was a correlation between BMI with histopathological subtypes and breast cancer grading, but the correlation tended to be weak. Whereas, with age, there was no correlation. BMI overweight-obese were more likely to have invasive carcinoma NST subtype and higher-grade of breast cancer.
Differentiation Between Glioblastoma Multiforme and Metastasis From the Lungs and Other Sites Using Combined Clinical/Routine MRI Radiomics
Authors: Han Yuqi , Zhang Lingling , Niu Shuzi , Chen Shuguang , Yang Bo , Chen Hongyan , Zheng Fei , Zang Yuying , Zhang Hongbo , Xin Yu , Chen Xuzhu 
Published: August 2021

BackgroundDifferentiation between cerebral glioblastoma multiforme (GBM) and solitary brain metastasis (MET) is important. The existing radiomic differentiation method ignores the clinical and routine magnetic resonance imaging (MRI) features.PurposeTo differentiate between GBM and MET and between METs from the lungs (MET-lung) and other sites (MET-other) through clinical and routine MRI, and radiomics analyses.Methods and MaterialsA total of 350 patients were collected from two institutions, including 182 patients with GBM and 168 patients with MET, which were all proven by pathology. The ROI of the tumor was obtained on axial postcontrast MRI which was performed before operation. Seven radiomic feature selection methods and four classification algorithms constituted 28 classifiers in two classification strategies, with the best classifier serving as the final radiomics model. The clinical and combination models were constructed using the nomograms developed. The performance of the nomograms was evaluated in terms of calibration, discrimination, and clinical usefulness. Student’s t-test or the chi-square test was used to assess the differences in the clinical and radiological characteristics between the training and internal validation cohorts. Receiver operating characteristic curve analysis was performed to assess the performance of developed models with the area under the curve (AUC).ResultsThe classifier fisher_decision tree (fisher_DT) showed the best performance (AUC: 0.696, 95% CI:0.608-0.783) for distinguishing between GBM and MET in internal validation cohorts; the classifier reliefF_random forest (reliefF_RF) showed the best performance (AUC: 0.759, 95% CI: 0.613-0.904) for distinguishing between MET-lung and MET-other in internal validation cohorts. The combination models incorporating the radiomics signature and clinical-radiological characteristics were superior to the clinical-radiological models in the two classification strategies (AUC: 0.764 for differentiation between GBM in internal validation cohorts and MET and 0.759 or differentiation between MET-lung and MET-other in internal validation cohorts). The nomograms showed satisfactory performance and calibration and were considered clinically useful, as revealed in the decision curve analysis.Data ConclusionThe combination of radiomic and non-radiomic features is helpful for the differentiation among GBM, MET-lung, and MET-other.
Impact of Chronobiological Variation in Takotsubo Syndrome: Prognosis and Outcome
Authors: El-Battrawy Ibrahim , Aweimer Assem , Lang Siegfried , Ansari Uzair , Gietzen Thorsten , Ullrich Niklas , Mügge Andreas , Zhou Xiaobo , Borggrefe Martin , Akin Ibrahim 
Published: August 2021

Background: A considerable amount of evidence has shown that acute cardiovascular diseases exhibit specific temporal patterns in their onset.Aim: This study was performed to determine if takotsubo syndrome (TTS) shows chronobiological variations with short and long-term impacts on adverse events.Design: Our institutional database constituted a collective of 114 consecutive TTS patients between 2003 and 2015.Methods: Patients were divided into groups defined by the onset of TTS as per time of the day, day of the week, month and quarter of year.Results: TTS events were most common afternoon and least common in the night, indicating a wave-like pattern (p = 0.001) of manifestation. The occurrence of TTS events was similar among days of the week and weeks of the month. TTS patients diagnosed in the month of November and subsequently in the fourth quarter showed a significantly longer QTc interval. These patients also revealed a significantly lower event-free-survival over a 1-year follow-up. In a multivariate Cox regression analysis, TTS events occurring in the fourth quarter of year (HR 6.8, 95%CI: 1.3–35.9; p = 0.02) proved to be an independent predictor of lower event-free-survival.Conclusions: TTS seems to exhibit temporal preference in its onset, but nevertheless this possibly coincidental result needs to be analyzed in a large multicenter registry.
Effectiveness of Telerehabilitation on Motor Impairments, Non-motor Symptoms and Compliance in Patients With Parkinson's Disease: A Systematic Review
Authors: Vellata Chiara , Belli Stefano , Balsamo Francesca , Giordano Andrea , Colombo Roberto , Maggioni Giorgio 
Published: August 2021

Introduction: Parkinson's disease (PD) is a chronic neurodegenerative disease involving a progressive alteration of the motor and non-motor function. PD influences the patient's daily living and reduces participation and quality of life in all phases of the disease. Early physical exercise can mitigate the effects of symptoms but access to specialist care is difficult. With current technological progress, telemedicine, and telerehabilitation is now a viable option for managing patients, although few studies have investigated the use of telerehabilitation in PD. In this systematic review, was investigated whether telerehabilitation leads to improvements in global or specific motor tasks (gait and balance, hand function) and non-motor dysfunction (motor speech disorder, dysphagia). The impact of TR on quality of life and patient satisfaction, were also assessed. The usage of telerehabilitation technologies in the management of cognitive impairment was not addressed.Method: An electronic database search was performed using the following databases: PubMed/MEDLINE, COCHRANE Library, PEDro, and SCOPUS for data published between January 2005 and December 2019 on the effects of telerehabilitation systems in managing motor and non-motor symptoms. This systematic review was conducted in accordance with the PRISMA guideline and was registered in the PROSPERO database (CRD42020141300).Results: A total of 15 articles involving 421 patients affected by PD were analyzed. The articles were divided into two categories based on their topic of interest or outcome. The first category consisted of the effects of telerehabilitation on gait and balance (3), dexterity of the upper limbs (3), and bradykinesia (0); the second category regarded non-motor symptoms such as speech disorders (8) and dysphagia (0). Quality of life (7) and patient satisfaction (8) following telerehabilitation programs were also analyzed, as well as feasibility and costs.Conclusion: Telerehabilitation is feasible in people affected by PD. Our analysis of the available data highlighted that telerehabilitation systems are effective in maintaining and/or improving some clinical and non-clinical aspects of PD (balance and gait, speech and voice, quality of life, patient satisfaction).Systematic Review Registration:https://www.crd.york.ac.uk/prospero/, identifier: CRD42020141300.
Gastric Electrical Dysarrhythmia in Probable Rapid Eye Movement Sleep Behavior Disorder
Authors: Peng Anjiao , Ji Shuming , Li Wanling , Lai Wanlin , Qiu Xiangmiao , He Shixu , Dong Bosi , Huang Cheng , Chen Lei 
Published: August 2021

Background: Subjective gastrointestinal complaints have been repeatedly reported in patients with REM sleep behavior disorder (RBD), but objective evidence is scarce. We aimed to objectively investigate the gastrointestinal dysfunction in individuals with probable RBD (pRBD) using an electrogastrogram.Methods: Thirty-two participants with pRBD and 60 age- and gender-matched healthy controls were enrolled. pRBD was diagnosed based on questionnaires and further assessed by experienced neurologists. After thorough assessment of participants' subjective gastrointestinal symptoms, preprandial and postprandial gastric activities were measured using an electrogastrogram. Dominant frequency, dominant power ratio, and the ratio of preprandial to postprandial power were analyzed.Results: Among the gastric symptoms, hiccup (34.8 vs. 9.6%, p = 0.017) and postprandial gastric discomfort (43.5 vs. 15.4%, p = 0.017) were more frequent in participants with pRBD than in controls. The dominant frequency on the electrode overlying the gastric pyloric antrum was lower in pRBD than in healthy controls (2.9 [2.6–2.9] vs. 2.9 [2.9–3.2] cpm, p = 0.006). A reduced dominant power ratio from the same electrode was also found in individuals with pRBD (60.7 [58.0–64.5] vs. 64.2 [58.7–69.6] %, p = 0.046).Conclusion: Patients with pRBD have a higher rate of gastric dysfunction, which presented as irregular slow wave rhythmicity on an electrogastrogram.
Intracranial Pressure and Cerebral Perfusion Pressure in Large Spontaneous Intracranial Hemorrhage and Impact of Minimally Invasive Surgery
Authors: Al-Kawaz Mais N. , Li Yunke , Thompson Richard E. , Avadhani Radhika , de Havenon Adam , Gruber Joshua , Awad Issam , Hanley Daniel F. , Ziai Wendy 
Published: August 2021

Introduction: We investigated the effect of hematoma volume reduction with minimally invasive surgery (MIS) on intracranial pressure (ICP) and cerebral perfusion pressure (CPP) in patients with large spontaneous intracerebral hemorrhage (ICH).Methods:Post-hoc analysis of the Minimally Invasive Surgery Plus Alteplase for Intracerebral Hemorrhage Evacuation (MISTIE III) study, a clinical trial with blinded outcome assessments. The primary outcome was the proportion of ICP readings ≥20 and 30 mmHg, and CPP readings &lt;70 and 60 mm Hg. Secondary outcomes included major disability (modified Rankin scale &gt;3) and mortality at 30 and 365 days. We assessed the relationship between proportion of high ICP and low CPP events and MIS using binomial generalized linear models, and outcomes using multiple logistic regression.Results: Of 499 patients enrolled in MISTIE III, 72 patients had guideline based ICP monitors placed, 34 in the MIS group and 38 in control (no surgery) group. Threshold ICP and CPP events ≥20/ &lt;70 mmHg occurred in 31 (43.1%) and 52 (72.2%) patients respectively. On adjusted analyses, proportion of ICP readings ≥20 and 30 mmHg were significantly lower in the MIS group vs. control group [Odds Ratio (OR) 0.27, 95% Confidence Interval [CI] 0.11–0.63 (p = 0.002); OR = 0.18, 0.04–0.75, p = 0.02], respectively. Proportion of CPP readings &lt;70 and 60 mm Hg were also significantly lower in MIS patients [OR 0.31, 95% CI 0.15–0.63 (p = 0.001); OR 0.30, 95% CI 0.11–0.83 (p = 0.02)], respectively. Higher proportions of CPP readings &lt;70 and 60 mm were significantly associated with short term mortality (p = 0.04), and (p = 0.006), respectively. Long term mortality was significantly associated with higher proportion of time with ICP ≥ 20 (p = 0.04), ICP ≥ 30 (p = 0.04), and CPP &lt;70 mmHg (p = 0.01).Conclusion: Our results are consistent with the hypothesis that surgical reduction of ICH volume decreases proportion of high ICP and low CPP events and that these variables are associated with short- and long-term mortality.