bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prognostic impact of the 18F-fluorodeoxyglucose positron-emission tomography/computed tomography metabolic parameters and correlation with hematological inflammatory markers in lung cancer
Authors: Goksel Sibel , Cengiz Arzu , Ozturk Hakan , Yurekli Yakup 
Published: July 2021

Introduction:
Hematological inflammatory markers and metabolic parameters in positron-emission tomography/computed tomography (PET/CT) are important indicators predicting the prognosis of the disease in lung cancer as in many cancers. This study aimed to evaluate the correlation between pretreatment hematological inflammatory markers and PET/CT metabolic parameters in nonsmall cell lung cancer (NSCLC) patients and to predict the prognostic value of these parameters.

Materials and Methods:
A total of 132 patients with diagnosed NSCLC who underwent PET/CT at staging were retrospectively evaluated. Hematological parameters were obtained from the hemogram taken no more than 2 weeks prior to PET/CT. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) were recorded. Maximum standard uptake value, SUVmean, metabolic tumor volume (MTV), and total lesion glycolysis (TLG) were calculated. Clinical stage, tumor pathology, and overall survival were analyzed with these parameters.

Results:
NLR and PLR were significantly positively correlated with MTV and TLG (all P < 0.001), MPV was negatively correlated with TLG (P = 0.021). While TLG, MTV, NLR, and PLR were increased in advanced stage disease, MPV was decreased. Univariate Cox-regression analysis demonstrated that greater age (P = 0.015), advanced stage (P < 0.001), low MPV (P = 0.017), high NLR (P < 0.001), PLR (P < 0.001), MTV (P = 0.004), TLG (P = 0.001) values, multivariate Cox-regression analysis revealed that NLR (P < 0.001) and advanced stage (P < 0.001) were significant predictors of poor prognosis in patients with NSCLC.

Conclusions:
There were significant associations between hematological inflammatory markers and PET/CT metabolic parameters in the patients with NSCLC at the time of diagnosis. These indicators can contribute to predicting prognosis in patients with NSCLC.
Prevalence of Ocular Surface Disease in Glaucoma Patients on Long-Term Antiglaucoma Medications
Authors: Abraham Emem G. , Udofia Inyene E. 
Published: July 2021

Objective:
Long term use of preservative-containing medications has been associated with the development or worsening of ocular surface disease (OSD). This study aimed to determine the prevalence of OSD in glaucoma patients on long-term antiglaucoma medications.

Methods:
A cross-sectional hospital-based study was carried out on 208 respondents using Ocular Surface Disease Index (OSDI) questionnaire, tear break-up time (TBUT), and Schirmer 1 test. Data analysis was done using Statistical Package for Social Science version 22.0 (SPSS Inc, Chicago, Illinois, USA).

Results:
The prevalence of OSD was higher in those on antiglaucoma medication using all modalities of assessment. Prevalence of OSD in glaucoma patients on antiglaucoma drugs was highest using TBUT- 69.2% (P = 0.031), with OSDI questionnaire it was 62.5% (P = 0.005), and it was lowest for Schirmer 1 test - 59.6%. For those nonglaucoma cases/not on any antiglaucoma medication, the prevalence using TBUT was 42.3%, using OSDI it was 16.3%, and with Schirmer 1 test it was 25.9%. Prevalence also increased with the increase in the number of eye drops from 1 to 2 drops/day using all modalities of assessment (P = 0.004). Using multivariate analysis, adjusting for sex and age, subjects who instilled 2 drops/day had four to five times the odds of having OSD.

Conclusion:
The prevalence of OSD is higher in patients with glaucoma on topical antiglaucoma medication than the nonglaucoma population studied and this increased with the increase in number of drops per day.
Exploring the Relationship Between Central Corneal Thickness and Intraocular Pressure Among Nonglaucoma Patients in a General Ophthalmology Clinic, South East Nigeria
Authors: Mbatuegwu Adaku I. , Achigbu Ebere O. , Mbatuegwu Chidi U. , Nkwogu Florence U. , Omoti Afekhide E. 
Published: July 2021

Context:
Glaucoma is an important cause of irreversible blindness and visual impairment in Nigeria. Studies have shown that intraocular pressure (IOP) is the only modifiable risk factor for glaucoma. The true IOP of an individual, in turn, is determined by the central corneal thickness (CCT).

Aim:
The aim of the study is to describe the relationship between IOP and CCT among nonglaucoma patients in Owerri, Imo State, Nigeria.

Methods:
This was a hospital-based, cross-sectional, analytical study done on nonglaucomatous patients aged 18 years and above. A comprehensive ocular examination was carried out for all participants and IOP was measured between 8 am and 12 noon to reduce the effect of diurnal variations.

Results:
Four hundred and twenty-two subjects with a mean age of 40.34 ± 14.468 years and a female to male ratio of 1.7:1 participated. The mean measured IOP was 16.77 ± 4.37 mmHg, and the mean CCT was 533.05 ± 33.92 μm. The mean corrected IOP was 17.61 ± 4.57 mmHg indicating a pattern of falsely low IOP. There was a positive, statistically significant correlation between IOP and CCT (P = 0.045).

Conclusion:
There was a positive correlation between IOP and CCT with the resultant effect that thin corneas presented with falsely low IOP and thick corneas with falsely high IOP. Routine CCT measurement in addition to IOP measurement should be done on every patient.
Utilization of Vision Corridor for Self-evaluation of Vision Among Secondary School Students in Igbo-Ora, Southwest Nigeria
Authors: Ugalahi Mary O. , Bekibele Charles O. , Ogundipe Ayobade O. 
Published: July 2021

Introduction:
Uncorrected refractive errors have been identified as a major cause of visual impairment with a high magnitude in developing countries, due to the paucity of eye care workers. To overcome this, different approaches like screening by non-eye care workers and self-assessment have been explored. This study aims to determine the utilization, reliability, and factors affecting the utilization of vision corridors among secondary school students.

Material and Methods:
An observational cross-sectional study conducted among students of Lasogba High School, Igbo-Ora, Southwest Nigeria. All the students received training on visual acuity assessment with the 6-meter Snellen’s chart. Thereafter, the chart with graphic instruction “Vision Corridor” was provided with a 4-week exposure period. All students who utilized the vision corridor recorded visual acuity in a register maintained by a community health extension worker. The utilization and factors that may have affected utilization were assessed after the exposure. Data were analyzed with the Statistical Package for Social Science version 15.

Results:
A total of 373 students completed the study; males accounted for 48.8% and females 51.2%. The mean age of the students was 15.2 (±2.2) years. A total of 151 (40.5%) students utilized the vision corridor and factors associated with utilization included being female, age ≤15 years, and being in a junior class, all of which were statistically significant.

Conclusion:
A moderate proportion of the students utilized the vision corridor. This approach to refractive error screening appears promising, as self-evaluation may reduce the need for skilled manpower in refractive error screening in secondary school students. Therefore, this may effectively utilize skilled eye care manpower for other eye care services in developing countries where there is a paucity of eye care workers.
COVID-19 Therapeutics for Low- and Middle-Income Countries: A Review of Candidate Agents with Potential for Near-Term Use and Impact
Authors: Maxwell Daniel , Sanders Kelly C. , Sabot Oliver , Hachem Ahmad , Llanos-Cuentas Alejandro , Olotu Ally , Gosling Roly , Cutrell James B. , Hsiang Michelle S. 
Published: July 2021

ABSTRACT.
Low- and middle-income countries (LMICs) face significant challenges in the control of COVID-19, given limited resources, especially for inpatient care. In a parallel effort to that for vaccines, the identification of therapeutics that have near-term potential to be available and easily administered is critical. Using the United States (US), European Union (EU), and World Health Organization (WHO) clinical trial registries, we reviewed COVID-19 therapeutic agents currently under investigation. The search was limited to oral or potentially oral agents, with at least a putative anti-SARS-CoV-2 virus mechanism and with at least five registered trials. The search yielded 1,001, 203, and 1,128 trials, in the US, EU, and WHO trial registers, respectively. These trials covered 13 oral or potentially oral repurposed agents that are currently used as antimicrobials and immunomodulatory therapeutics with established safety profiles. The available evidence regarding proposed mechanisms of action, potential limitations, and trial status is summarized. The results of the search demonstrate few published studies of high quality, a low proportion of trials completed, and the vast majority with negative results. These findings reflect limited investment in COVID-19 therapeutics development compared with vaccines. We also identified the need for better coordination of trials of accessible agents and their combinations in LMICs. To prevent COVID-19 from becoming a neglected tropical disease, there is a critical need for rapid and coordinated efforts in the evaluation and deployment of those agents found to be efficacious.
Arsenic contamination in India: Causes, effects and treatment methods
Authors: Tiwari Rishabh , Satwik Satwik , Khare Prateek , Rai Satyam 
Published: July 2021

Herein the present study focuses on arsenic (As) contamination in groundwater, which plagues a vast section of the population of the world. Even the conservative estimates by the World Health Organization (WHO) estimate the number of people plagued by arsenic contaminated drinking water to be around 140-200 million. The Ganga- Brahmaputra fluvial plains in India and Padma-Meghna fluvial plains in Bangladesh are said to be one of the worst groundwater calamities to the humans. The Arsenic levels in drinking water in some of the most populated states in India are disproportionately higher than those defined by WHO guidelines. The paper, thus, delves into the anomaly in permissible limits defined by WHO and regional governments and its consequential effects. It briefly analyses the major sources of Arsenic contamination and its health effects in India. The study also looks closely into the states and districts plagued by the As contamination and explores the prominent treatment methods employed in as removal from the drinking water.
Keywords: Arsenic, Adsorption, Geogenic, Arsenopyrite, Oxidation treatment
The Obligatory Underwater Level: Posthuman Genealogy of Amphibian Human in Media
Authors: Serada Alesha Alesha 
Published: July 2021

Will humankind ever be able to live underwater? To answer this question from the perspective of visual media studies, I analyze narrative and expressive means used for positive representation of underwater experiences in several examples of screen media. My examples are principally different by origin and yet united by their highly enjoyable effect of immersion into underwater worlds. My primary focus is on Amphibian Man (1928), a cult early science fiction novel by Alexandr Belyaev adapted for screen in 1962 in the USSR.I also explore its unintentionally close contemporary reproduction in The Shape of Water (2016), which even led to accusations in plagiarism. The third example is a contemporary independent video game ABZU by Giant Squid (2016), which replays the same theme of amphibian human existence in a positive light. These cases present a surprisingly rare view of a safe, friendly and interactive marine world, approached by the protagonist who can breathe underwater. I apply the posthumanist lens to find out that, surprisingly, aquatic cyborgs seem to be underrated by the queer thought (Haraway, 2015, 2016); I conclude that the model of ‘queer ecologies’ may become the needed development.
THE MEDIATING EFFECT OF JOB SATISFACTION ON THE IMPACT OF ORGANIZATIONAL SPIRITUALITY ON JOB PERFORMANCE
Authors: Yarım Mehmet Ali 
Published: July 2021

<p>The aim of this study is to determine the mediating effect of job satisfaction on teachers' effect of organizational spirituality on job performance. The study group of the study consists of 320 teachers who are selected by appropriate sampling method among the teachers working in primary schools in the central districts of Erzurum province (Yakutiye, Palandöken, Aziziye). Organizational Spirituality Scale, Minnesota Job Satisfaction Scale and Job Performance Scale were used to collect data in the study. SPSS 24 and Amos programs were used to analyze the data obtained during the research process. As a result of the research, it has been determined that organizational spirituality has positive and significant effects on job satisfaction and job performance, and job satisfaction has positive effects on job performance. In addition, it was concluded that there is a partial mediation effect of job satisfaction on the effect of organizational spirituality on job performance.</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0820/a.php" alt="Hit counter" /></p>
SOCIAL STUDIES TEACHERS’ PEDAGOGICAL CONTENT KNOWLEDGE AND ITS INFLUENCE ON THEIR ASSESSMENT PRACTICES IN JUNIOR HIGH SCHOOLS IN THE WEST AKIM MUNICIPALITY, GHANA
Authors: Ghanney Robert Andrews , Agyei Edward Boafo 
Published: July 2021

<p>The study examined Social Studies teachers’ pedagogical content knowledge and its influence on their assessment practices in Junior High Schools in the West Akim Municipality in the Eastern Region of Ghana. The study was hinged on the Pedagogical Content Knowledge (PCK) model by Shulman, (1986) and adopted the concurrent triangulation design with mixed methods approach. The census and convenience sampling techniques were used to select seventy-seven (77) and ten (10) respondents respectively for the study. Questionnaire, observation check list and document analysis were used by the researchers as instruments for data collection. These instruments were used to enable the researchers triangulate the information to test the consistency of the findings. A reliability analysis using Cronbach’s Alpha was performed to determine the internal consistency of each construct in the questionnaire and the observation checklist. The data obtained from the three instruments were analysed using descriptive statistics (frequency counts, percentages, mean and standard deviation). Inferential statistics (Pearson Product Moment Correlation) was used to test the stated hypothesis. The results indicated that generally, most of the JHS Social Studies teachers possessed some level of pedagogical content knowledge. Again, Social Studies teachers practice traditional assessment method (pen/pencil and paper). The results further pointed out that pedagogical content knowledge influence teachers’ assessment practices (r = .819**, sig. =.000** p &lt; 0.05, CI=95%, n=77, 2-tailed). It is recommended that Social Studies teachers within the West Akim Municipality should make use of alternative assessment techniques as these other techniques will help cater for affective and psychomotor assessments which will help develop pupils’ attitudes and values.</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0788/a.php" alt="Hit counter" /></p>
PARENTING STYLES OF IN-SCHOOL ADOLESCENTS IN SOUTH-EAST NIGERIA
Authors: Chigbu Eberechukwu Francisca , Nwobi Ngozika Lovina , Ngwaka Loveth Chinasa , Mokwelu Blessing Obianuju 
Published: July 2021

<p>The study investigated parenting styles of in-school adolescents in south-East, Nigeria. Three research questions were formulated to guide the study at .05 level of significance. The study adopted a survey research design. The population for the study consisted 137,095 in-school adolescents in secondary school in South East, Nigeria. The sample for the study was 1200 senior secondary school II adolescents. The instrument for data collection was a 53-item questionnaire. The instrument was validated by three experts, two from the department of educational foundations, and one from the department of science education, all from faculty of Education, University of Nigeria, Nsukka. Mean and standard deviation were used for data analysis. The study reveals, among others, that the parenting styles in-school adolescents were exposed to were authoritative, authoritarian and permissive. The study recommended, among others, that more school counselors should be employed and retained through in-service training programmes, capacity building workshops and refresher courses on adolescent value and moral upbringing. </p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0779/a.php" alt="Hit counter" /></p>
KARST IN URBAN AREAS
Authors: BEYNE PHILIP VAN , CLAUDINO-SALES VANDA , VITAL SAULO ROBERTO DE OLIVEIRA , VALADARES DIEGO NUNES 
Published: July 2021

In its third edition, the “William Morris Davis – Journal of Geomorphology” presents its second interview with geographers, to head the “Interviews” section, which opens each published issue. This time, it is the first international interview, carried out with Professor Philip van Beynen, from the University of South Florida, in the United States. Professor Philip van Beynen was interviewed on the topic “Karst in Urban Areas”, and brings important data on the subject, with beautiful illustrations and with examples from all over the world. The interview took place on September 17, 2020, with the participation of Vanda de Claudino-Sales (Professor of the Academic Master in Geography at the State University of Vale do Acarau-UVA) and Saulo Roberto Oliveira Vital (Professor of the Department of Geography and the Post-Graduate Program in Geography at the Federal University of Paraiba - UFPB), and was transcribed by Diego Nunes Valadares, master's student on Geography at the Federal University of Rio Grande do Norte.
Professor van Beynen was born in New Zealand, where he received his degree in Geography at the University of Auckland. He earned a master's degree from the same university, and a doctorate and post-doctorate from McMaster University, Canada. He has been a professor at the School of Geoscience at the University of South Florida since 2009, where he has been developing research related to different components of karst environments. The interview shows his great expertise on the subject, and is very much worth to be read and seen even for those who are not specialists in karst.
Statistical analysis of waiting time of patients by queuing techniques: case study of large hospital in Pakistan
Authors: Kalwar Muhammad Ahmed , Memon Muhammad Saad , Khan Muhammad Ali , Tanwari Anwaruddin 
Published: July 2021

<p class="JARTEAbstractHeader">The purpose of this empirical research was to analyze the comfortable waiting time (CWT) of patients at the outpatient department (OPD) of Gastrology of ABC hospital of Karachi. It is based on the analysis of CWT of patients who were being served at the OPD of Gastrology of ABC hospital of Karachi. The data was collected by the help of questionnaire. Altogether 250 questionnaires were distributed among the patients, 210 of them were collected back and 10 of them were incompletely filled. Data was analysed in the statistical package for social sciences (SPSS) version 22. Data analysis included frequency distribution of various demographics;stratification tables were made for the comparison of CWT across various demographics. Results indicated that more females (old aged) had greater CWT in the comparison of males. It is found that the mean CWT of patients decreased with decreasing age, increasing OPD visiting time and increasing income. It is also found that he mean CWT for the patients from Afghanistan was greater than the patients from other regions i.e. Baluchistan, interior Sindh and Karachi. The authors highlighted that when patients arrive at the hospital and wait for their service, in this scenario, waiting cost is associated with their waiting time; since it is the matter of cost, thus it should be known to the hospital that if patients are made to wait longer, it can lead to the customer dissatisfaction. In this regard, analysis of comfortable waiting time of patients was extremely needed. Since, Karachi is the biggest city of Pakistan and targeted hospital is one the biggest private hospitals of Karachi and in the analysis of this paper. Only 200 patients were approached for data collection which is the main limitation of the paper. In future, the researchers should also focus on the same OPD for more responses and at the same time, other departments can also be targeted for conclude better and precise results. The authors have tried to focus on the CWT of patients so that the waiting capacity of patients could be highlighted. At the same time, detailed analysis was conducted across demographics so that their influence on CWT could be analysed.</p><p class="JARTEKeywords"> </p>
Klucht, satire en ernst
Authors: Hupperts Charles 
Published: July 2021

Summary
This paper examines the themes of Plato´s Symposium and the general functions of the first five speeches. It also discusses the importance of the person of Socrates as a subject of the dialogue and his connexion to eros. Eros and Socrates together form the focus of the Symposium. The second part of this article analyses the speech of Aristophanes in detail. This funny speech has several functions: Plato uses the speech to develop a general notion of eros which is interesting and worthwhile to reflect upon. The myth offers an explanation for the three kinds of sexual identity, but also for things like promiscuity, the function of sexuality and the feeling that eros is more than just sex. Eros is a force regulating human life.
At the same time, his speech is a defence of homosexual love, a rather strange position for someone who usually paints a very negative picture of homosexuality in his comedies. The article aims to demonstrate that Aristophanes is ridiculing himself in the Symposium. The things he says in his speech are the opposite of his own ideas. In fact, Plato treats Aristophanes in the same way as the poet of comedies treated Socrates in the Clouds. So this speech, too, is related to Socrates.
Een beetje onsterfelijk
Authors: Boter Gerard 
Published: July 2021

Summary
The present article discusses three hotly debated interpretational issues in Diotima´s speech in Plato´s Symposium. The first of these is the relationship of Diotima´s speech to other dialogues, such as the Phaedo and the Republic, with regard to the immortality of the soul. It is argued that there is no discrepancy at all, because the immortality of the soul does not play any role in the Symposium. The second issue is the nature of the three classes of posterity: biological, spiritual and philosophical. Whereas the posterity of the first two classes can be relatively easily defined, the character of the philosopher´s posterity, ‘true virtue’, remains rather vague. It may consist in dialectical teaching of the Idea of Beauty by Socrates. Thirdly, it is argued that the philosopher´s immortality differs only gradually from the immortality of the other two classes, that is, the philosopher as a man only survives by means of his posterity.