bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deep phylogeographic splits but no taxonomic structure in the disjointly distributed Draba pacheri (Brassicaceae), a subendemic of the Eastern Alps
Authors: Kucs Erich , Schönswetter Peter , Schneeweiss Gerald M. 
Published: November 2021

AbstractDraba (Brassicaeae), a model group for diversification and evolution in Arctic and mountain habitats, is taxonomically challenging and many of its species are insufficiently investigated. One such species is D. pacheri, an endemic of the eastern European Alps and the western Carpathians (here presumably extinct). Several hypotheses exist with respect to the phylogenetic position and the taxonomy of this species, but none of these has ever been tested using molecular data. In this article we examine (i) DNA sequence data to assess the phylogenetic position of D. pacheri within the genus and (ii) AFLP fingerprint data as well as morphometric data to address whether this species can be divided taxonomically into species or subspecies. DNA sequence data firmly place D. pacheri within the Core Draba Group III, whose internal relationships are, however, insufficiently resolved to precisely identify the closest relative of D. pacheri. AFLP data identify several genetically divergent lineages corresponding to geographically distinct regions. Although these lineages are congruent with hypotheses distinguishing either two species (D. pacheri s. str., D. norica) or one species with several subspecies, the lack of clear morphological separation, both with respect to the entire set of traits and single presumably diagnostic characters such as trichome morphology, renders recognition of a single species D. pacheri, as suggested previously, the best taxonomic solution. The deep and geographically strongly structured splits of D. pacheri likely are the result of isolation in several Pleistocene refugia and warrant that conservation efforts should involve populations from each of the main geographic subgroups.
Focal neuroendocrine carcinoma mixed with adenocarcinoma of the gallbladder with aggressive lymph node metastasis in a patient who did not meet the mixed neuroendocrine–non-neuroendocrine neoplasm criteria
Authors: Kadota Yoshie , Funakoshi Shinsuke , Hirose Shigemichi , Shiomi Eisuke , Odaira Masanori , Yagishita Haruka , Kobayashi Yosuke , Toriumi Fumiki , Tamai Seiichi , Endo Takashi , Harada Hirohisa 
Published: November 2021

AbstractA 70-year-old Japanese woman who was treated for interstitial pneumonia (IP) with steroid therapy developed cholecystitis. A serial computed-tomography (CT) imaging showed irregular thickness of the fundus wall of the gallbladder and two rapidly enlarged lymph nodes (LNs): number (no.) 12 and no. 8a. Positron-emission tomography-computed tomography (PET-CT) scan showed an abnormal uptake at the site of the gallbladder tumor and those LNs. We subsequently performed open radical cholecystectomy and LN dissection of the no. 12 and 8a LNs, following complete remission of IP. The histology showed gallbladder adenocarcinoma, with a single focus of neuroendocrine carcinoma (NEC) component of less than 30%; Ki-67 index > 80%, synaptophysin (Syn) (+), chromogranin A (CgA) (+), and clusters of differentiation (CD) 56 (+) (T2bN1M0, Stage IIIB). LN no. 8a was diffusely metastatic with NEC components. LN no. 12c, which was adjacent to the cystic duct, revealed necrosis without apparent tumor cells, but was highly suspicious for tumor necrosis. The final diagnosis was adenocarcinoma of the gallbladder with focal NEC (< 30%), which did not meet the criteria for mixed neuroendocrine–non-neuroendocrine neoplasm (MiNEN). Postoperatively, she completed 4 cycles of adjuvant chemotherapy for NEC (Cisplatin plus Etoposide), and no recurrence was observed after 12 months.
Aeroelastic simulations of a delta wing with a Chimera approach for deflected control surfaces
Authors: Reinbold Christopher , Sørensen Kaare , Breitsamter Christian 
Published: November 2021

AbstractA numerical tool for the computation of aircraft control surface aerodynamics with flexibility effects is presented. The solution is based on coupled Computational Fluid Dynamics (CFD) and Computational Structural Mechanics (CSM) simulations embedded in the multidisciplinary simulation environment SimServer. In SimServer, the DLR-TAU Code is utilized to obtain the CFD solution by solving the Reynolds-Averaged Navier–Stokes (RANS) equations. Structural displacements are computed with a modal solver. The Chimera implementation of SimServer, suited for hybrid grids, is applied to model the control surfaces. Numerical simulations with the flexible Chimera method are performed for the Model53 wing configuration, which is a generic delta wing with a deployed slat as well as an inboard and outboard trailing edge flap. Aerodynamic and aeroelastic simulations at high dynamic pressure $$q=45$$

q
=
45

kPa and transonic speed $${\text {Ma}} = 0.8$$

Ma
=
0.8

are performed for several angles of attack $$10^\circ \le \alpha \le 25^\circ$$

10
∘

≤
α
≤

25
∘

and flap deflection angles $$-30^\circ \le \delta \le 30^\circ$$

-

30
∘

≤
δ
≤

30
∘

. The effect of structural deformations on the flow field and control surface effectiveness are analyzed and compared to computations of components treated fully rigid. At the targeted freestream condition $$M=0.8$$

M
=
0.8

and $${\text {Re}}=15.1 \times 10^7$$

Re
=
15.1
×

10
7

, the flow field around the Model53 configuration is characterized by the interaction of vortices and shock waves. The results of the lift and pitching moment coefficient for the rigid and flexible configuration revealed the importance of taking the structural flexibility into account in order to obtain more accurate results for the considered range of flap deflections. Furthermore, the computational effort of the aerodynamic and aeroelastic simulations are evaluated. The increase in computational effort is shown to be adequate for the given increase in accuracy.
Statistical analysis of sub-zero temperature effects on fatigue strength of welded joints
Authors: Braun Moritz 
Published: November 2021

Abstract
Ships and offshore structures in Arctic environments are exposed to severe environmental actions and sub-zero temperatures. Thus, the design of such structures has to account for the Arctic environment and must be cost-efficient at the same time. A vital part of the design process is to ensure that fatigue-induced failure does not occur in the lifetime of the structure. While effects of high temperatures on material behavior are well covered in international standards and guidelines, there is no comprehensive guidance for sub-zero temperature fatigue strength assessment. Additionally, stress-life (S–N) test data of welded joints at sub-zero temperatures is particularly scarce. Hence, this study presents an extensive review of recent test results of various weld details tested in the range of − 50 to 20 °C. This data could build the basis for future considerations of temperature effects in fatigue design guidelines and recommendations. For this purpose, the fatigue test results are submitted to a rigorous statistically assessment—including a summary of the limitations of current design guidelines with respect to sub-zero temperature effects.
The Impact of Executives’ Gender, Financial Incentives, and Shareholder Pressure on Corporate Social and Ecological Investments
Authors: Theis Jochen , Nipper Marvin 
Published: November 2021

AbstractArchival research suggests that female executives have an impact on corporate decision-making and generally finds positive associations between female board representation and Corporate Social Responsibility (CSR) performance. However, archival research does not reveal why female executives decide differently in the context of CSR. As this is our starting point, we conduct an experiment and examine executives’ decision-making in terms of CSR investment. While female executives seem to be more oriented towards social and ecological practices, we find strong evidence that participants’ real-world incentive program mainly drives their CSR decision-making. We also examine if selected gender-specific character traits (risk propensity, sustainability attitude, and empathy) cause gender differences in executives’ CSR decision-making. In an exploratory analysis, we furthermore show that executives’ risk propensity affects their CSR decision-making conditional on the level of shareholder pressure they face. Our study contributes to the literature on executives’ decision-making and to the CSR literature by enhancing our understanding of determinants of executives’ CSR decision-making.
On MSE-Optimal Circular Crossover Designs
Authors: Neumann C. , Kunert J. 
Published: November 2021

AbstractIn crossover designs, each subject receives a series of treatments, one after the other inpconsecutive periods. There is concern that the measurement of a subject at a given period might be influenced not only by the direct effect of the current treatment but also by a carryover effect of the treatment applied in the preceding period. Sometimes, the periods of a crossover design are arranged in a circular structure. Before the first period of the experiment itself, there is a run-in period, in which each subject receives the treatment it will receive again in the last period. No measurements are taken during the run-in period. We consider the estimate for direct effects of treatments which is not corrected for carryover effects. If there are carryover effects, this uncorrected estimate will be biased. In that situation, the quality of the estimate can be measured by the mean square error, the sum of the squared bias and the variance. We determine MSE-optimal designs, that is, designs for which the mean square error is as small as possible. Since the optimal design will in general depend on the size of the carryover effects, we also determine the efficiency of some designs compared to the locally optimal design. It turns out that circular neighbour-balanced designs are highly efficient.
A Reflection on Community Research and Action as an Evolving Practice
Authors: Fawcett Stephen B. 
Published: November 2021

AbstractCommunity research and action is an evolving field of practice with multiple influences. Its varied ways of knowing and doing reflect recombined elements from different disciplines, including behavioral science, community psychology, public health, and community development. This article offers a personal reflection based on my evolving practice over nearly 50 years. The focus is on three types of influence: (a) engaging with different communities, fields, and networks (e.g., discovering shared values, diverse methods); (b) building methods and capabilities for the work (e.g., methods for participatory research, tools for capacity building); and (c) partnering for collaborative research and action, locally and globally. This story highlights the nature of the field’s evolution as an increasing variation in methods. Our evolving practice of community research and action—individually and collectively—emerges from the recombination of ideas and methods discovered through engagement in a wide variety of contexts.
Precarious Hope: Situated Perspectives on the COVID-19 Pandemic from Undergraduate Students in Manchester, UK
Authors: Nunn Caitlin , Germaine Chloe , Ogden Charlotte , Miah Yasmin , Marsh Jessica , Kitching Rhiannon , Kathrada Nasira , Hough Katerina , Harper Isabel 
Published: November 2021

AbstractThe COVID-19 pandemic has had a profound impact on the lives of young people, transforming and disrupting education provision, employment opportunities, social practices, mobilities, and experiences of health and well-being. In the UK context, the pandemic can be understood as both a unique event and as a further addition to the intersecting crises—including austerity and Brexit—that are increasingly shaping and constraining youth experiences and aspirations and exacerbating precarity and inequality. In this article, seven undergraduate students from Manchester, UK, with two academic co-authors, employ a co-productive approach to reflect on our experiences of the pandemic. Our autoethnographic accounts draw attention to the situated effects of the pandemic, and its intersection with existing challenges and pressures, including the gig economy, mental and physical ill health, and transnational family networks. At the same time, our narratives capture a sense of precarious hope: hopefulness that is both a product of precarity and itself precarious, opening up new possibilities for collectively imagining and pursuing viable and meaningful futures in uncertain times. Supporting our endeavours requires the inclusion of youth voices in research, policy, and practice; work we begin here.
Method for assessing the impact of rainfall depth on the stormwater volume in a sanitary sewage network
Authors: Kozłowski Edward , Kowalski Dariusz , Kowalska Beata , Mazurkiewicz Dariusz 
Published: November 2021

Abstract
Sanitary sewage network is relatively rarely considered as the cause of urban floods. Its hydraulic overload can result not only in flooding, but also sanitary contamination of subcatchments. Stormwater is the main reason for this overload. In contrast to the stormwater or combined sewer system, these waters infiltrate into the network in an uncontrolled way, through ventilation holes of covers or structural faults and lack of tightness of manholes. Part of stormwater infiltrates into the soil, where it leaks into pipelines. This greatly hinders assessing the quantity of stormwater influent into the sanitary sewer system. Standard methods of finding correlation between rainfall and the intensity of stormwater flow are ineffective. This is confirmed, i.a. by the studies performed in an existing network, presented in this paper. Only when residuals analysis was performed using the ARIMA and ARIMAX methods, the authors were able to develop a mathematical model enabling to assess the influence of rainfall depth on the stormwater effluent from the sewage network. Owing to the possibility of using the rainfall depth forecasts, the developed mathematical model enables to prepare the local water and sewerage companies for the occurrence of urban floods as well as hydraulic overload of wastewater treatment plants.
The development of luminescent solar concentrator-based photomicroreactors: a cheap reactor enabling efficient solar-powered photochemistry
Authors: Zondag Stefan D. A. , Masson Tom M. , Debije Michael G. , Noël Timothy 
Published: November 2021

AbstractSunlight strikes our planet every day with more energy than we consume in an entire year. Therefore, many researchers have explored ways to efficiently harvest and use sunlight energy for the activation of organic molecules. However, implementation of this energy source in the large-scale production of fine chemicals has been mostly neglected. The use of solar energy for chemical transformations suffers from potential drawbacks including scattering, reflections, cloud shading and poor matches between the solar emission and absorption characteristics of the photochemical reaction. In this account, we provide an overview of our efforts to overcome these issues through the development of Luminescent Solar Concentrator-based PhotoMicroreactors (LSC-PM). Such reactors can efficiently convert solar energy with a broad spectral distribution to concentrated and wavelength-shifted irradiation which matches the absorption maximum of the photocatalyst. Hence, the use of these conceptually new photomicroreactors provides an increased solar light harvesting capacity, enabling efficient solar-powered photochemistry.Graphical abstract
Survey of physician and pharmacist steward perceptions of their antibiotic stewardship programs
Authors: Burrowes Shana A. B. , Drainoni Mari-Lynn , Tjilos Maria , Butler Jorie M. , Damschroder Laura J. , Goetz Matthew Bidwell , Madaras-Kelly Karl , Reardon Caitlin M. , Samore Matthew H. , Shen Jincheng , Stenehjem Edward , Zhang Yue , Barlam Tamar F. 
Published: November 2021

Abstract

Objective:
To examine how individual steward characteristics (eg, steward role, sex, and specialized training) are associated with their views of antimicrobial stewardship program (ASP) implementation at their institution.

Design:
Descriptive survey from a mixed-methods study.

Setting:
Two large national healthcare systems; the Veterans’ Health Administration (VA) (n = 134 hospitals) and Intermountain Healthcare (IHC; n = 20 hospitals).

Participants:
We sent the survey to 329 antibiotic stewards serving in 154 hospitals; 152 were physicians and 177 were pharmacists. In total, 118 pharmacists and 64 physicians from 126 hospitals responded.

Methods:
The survey was grounded in constructs of the Consolidated Framework for Implementation Research, and it assessed stewards’ views on the development and implementation of antibiotic stewardship programs (ASPs) at their institutions We then examined differences in stewards’ views by demographic factors.

Results:
Regardless of individual factors, stewards agreed that the ASP added value to their institution and was advantageous to patient care. Stewards also reported high levels of collegiality and self-efficacy. Stewards who had specialized training or those volunteered for the role were less likely to think that the ASP was implemented due to a mandate. Similarly volunteers and those with specialized training felt that they had authority in the antibiotic decisions made in their facility.

Conclusions:
Given the importance of ASPs, it may be beneficial for healthcare institutions to recruit and train individuals with a true interest in stewardship.
Partially hyperbolic diffeomorphisms and Lagrangian contact structures
Authors: MION-MOUTON MARTIN 
Published: November 2021

AbstractIn this paper, we classify the three-dimensional partially hyperbolic diffeomorphisms whose stable, unstable, and central distributions
$E^s$
,
$E^u$
, and
$E^c$
are smooth, such that
$E^s\oplus E^u$
is a contact distribution, and whose non-wandering set equals the whole manifold. We prove that up to a finite quotient or a finite power, they are smoothly conjugated either to a time-map of an algebraic contact-Anosov flow, or to an affine partially hyperbolic automorphism of a nil-
${\mathrm {Heis}}{(3)}$
-manifold. The rigid geometric structure induced by the invariant distributions plays a fundamental part in the proof.
Metabolomics profiles of premenopausal women are different based on O-desmethylangolensin metabotype
Authors: Frankenfeld Cara L. , Maskarinec Gertraud , Franke Adrian A. 
Published: November 2021

AbstractUrinary O-desmethylangolensin (ODMA) concentrations provide a functional gut microbiome marker of dietary isoflavone daidzein metabolism to ODMA. Individuals who do not have gut microbial environments that produce ODMA have less favourable cardiometabolic and cancer risk profiles. Urinary metabolomics profiles were evaluated in relation to ODMA metabotypes within and between individuals over time. Secondary analysis of data was conducted from the BEAN2 trial, which was a cross-over study of premenopausal women consuming 6 months on a high and a low soya diet, each separated by a 1-month washout period. In all of the 672 samples in the study, sixty-six of the eighty-four women had the same ODMA metabotype at seven or all eight time points. Two or four urine samples per woman were selected based on temporal metabotypes in order to compare within and across individuals. Metabolomics assays for primary metabolism and biogenic amines were conducted in sixty urine samples from twenty women. Partial least-squares discriminant analysis was used to compare metabolomics profiles. For the same ODMA metabotype across different time points, no profile differences were detected. For changes in metabotype within individuals and across individuals with different metabotypes, distinct metabolomes emerged. Influential metabolites (variables importance in projection score > 2) included several phenolic compounds, carnitine and derivatives, fatty acid and amino acid metabolites and some medications. Based on the distinct metabolomes of producers v. non-producers, the ODMA metabotype may be a marker of gut microbiome functionality broadly involved in nutrient and bioactive metabolism and should be evaluated for relevance to precision nutrition initiatives.
Geochronology, geochemistry and tectonic implications of early Carboniferous plutons in the southwestern Alxa Block
Authors: Wang Zeng-Zhen , Chen Xuan-Hua , Shao Zhao-Gang , Li Bing , Chen Hong-Xu , Ding Wei-Cui , Zhang Yao-Yao , Wang Yong-Chao 
Published: November 2021

AbstractThe southeastern Central Asian Orogenic Belt (CAOB) records the assembly process between several micro-continental blocks and the North China Craton (NCC), with the consumption of the Paleo-Asian Ocean (PAO), but whether the S-wards subduction of the PAO beneath the northern NCC was ongoing during Carboniferous–Permian time is still being debated. A key issue to resolve this controversy is whether the Carboniferous magmatism in the northern NCC was continental arc magmatism. The Alxa Block is the western segment of the northern NCC and contiguous to the southeastern CAOB, and their Carboniferous–Permian magmatism could have occurred in similar tectonic settings. In this contribution, new zircon U–Pb ages, elemental geochemistry and Sr–Nd isotopic analyses are presented for three early Carboniferous granitic plutons in the southwestern Alxa Block. Two newly identified aluminous A-type granites, an alkali-feldspar granite (331.6 ± 1.6 Ma) and a monzogranite (331.8 ± 1.7 Ma), exhibit juvenile and radiogenic Sr–Nd isotopic features, respectively. Although a granodiorite (326.2 ± 6.6 Ma) is characterized by high Sr/Y ratios (97.4–139.9), which is generally treated as an adikitic feature, this sample has highly radiogenic Sr–Nd isotopes and displays significantly higher K2O/Na2O ratios than typical adakites. These three granites were probably derived from the partial melting of Precambrian continental crustal sources heated by upwelling asthenosphere in lithospheric extensional setting. Regionally, both the Alxa Block and the southeastern CAOB are characterized by the formation of early Carboniferous extension-related magmatic rocks but lack coeval sedimentary deposits, suggesting a uniform lithospheric extensional setting rather than a simple continental arc.