bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modern methods of surgical treatment of anal canal and rectum combined pathology
Authors: Balytskyy V. V. , Zakharash M. P. , Kuryk O. G. 
Published: June 2021

Objective. To evaluate the effectiveness of surgical treatment of anal canal and rectum combined pathology, through combined surgical interventions using modern electro- and radiosurgical technologies.
Materials and methods. A comparative evaluation of the results of surgical treatment of 681 patients with combined pathology of the anal canal and rectum, who underwent combined single-stage operations using high-frequency electrosurgery and radio-wave surgery.
Results. In case of application the device for radio-wave surgery "Surgitron", and also devices of high-frequency electrosurgery "ERBE ICC 200", "EFA", "KLS Martin" duration of operation is reduced to (15 - 25 ± 3) minutes, volume of blood loss decreases to (15 ± 6) ml, the need for narcotic analgesics decreases up to (2 ± 1) ml, the duration of inpatient treatment was reduced up to (4 ± 1) days.
Conclusions. The use of modern radio- and electrosurgical technologies for the treatment of combined anorectal pathology prevents the occurrence of anal canal strictures and scarring of the perianal areas, causing the cosmeticity of combined operations.
Endogenous intoxication indicators in advanced peritonitis and their correction
Authors: Mammadova E. T. 
Published: June 2021

Objective. To study the lipid peroxidation processes and endogenous intoxication indicators in patients with widespread peritonitis before surgery and during the treatment.
Materials and methods. The study included 97 patients (43 men and 54 women) aged from 17 to 69 years with purulent peritonitis. According to treatment scheme, patients were divided into two groups. Patients in group 1 received standard treatment, and in patients in group 2 standard treatment was supplemented by immunoreactions. The concentration of diene conjugates and malonic dialdehyde, reduced glutathione, catalase activity and the concentration of medium molecular weight peptides were determined in the blood of patients and almost healthy people.
Results. The concentration of diene conjugates, malonic dialdehyde and medium molecular weight peptides in the blood of patients with advanced peritonitis increased significantly depending on the clinical stage of the disease, while the activity of the enzyme catalase and the concentration of reduced glutathione were decreased.
Conclusions. Immunoreactions in combination with standard treatment leads to normalization of lipid peroxidation and reduction of endogenous intoxication on the 5th and 10th days of treatment.
Gender disparities in colorectal polyps
Authors: Safiyeva A. K. 
Published: June 2021

Objective. The main objective of the research is the pathohistological consequences of colorectal adenomatosis polyps and their gender-based assessment. Gender and its connection with advanced colorectal displasia are the focus of the research study.
Materials and methods. A retrospective analysis was conducted 100 patients. The age group of the patients in the research study mainly encompassed 19 to 65 aged patients. During the medical procedure, the gender distribution of the cases was determined as 60 males and 40 females respectively.
Results. There is strong evidence for an association between gender and the risk of advanced colorectal neoplasia. The findings regarding the positive interrelation for gender and advanced colorectal neoplasia are consistent with other large colonoscopy-based studies.
Conclusions. As a result of the study, we would like to emphasize that colorectal polyps are more common in men compared to in women
Ferdinand Gottlob Schichau i jego stocznia
Authors: Borzestowski Waldemar 
Published: June 2021

Ferdinand Gottlob Schichau swoją zawrotną karierę zawdzięczał niezwykłej pracowitości, energii, a także wybitnym uzdolnieniom. Urodzony w 1814 r. w Elblągu, był absolwentem Królewskiego Instytutu Technicznego (Königliches Gewerbe­­‑Institut) w Berlinie. Podczas zagranicznego stypendium zapoznał się z wiodącymi kierunkami industrializacji w Europie, zafascynowała go produkcja maszyn parowych i ich wykorzystywanie w przemyśle. Odrzucił propozycję zatrudnienia w dużym przedsiębiorstwie, pragnął budować wszystko od podstaw, samodzielnie. W 1837 r. założył w Elblągu mały Zakład Budowy Maszyn, pracowało w nim ośmiu mężczyzn. Taki był początek firmy, która pod koniec wieku zatrudniała tysiące robotników. Obdarzony genialnym wyczuciem nie tylko w zakresie nowinek technicznych, ale również koniunktury, F.G. Schichau wszystkie swoje przedsięwzięcia doprowadził do pełnego rozkwitu. W 1893 r. w przemysłowym krajobrazie Gdańska zaistniała nowa struktura, stocznia Schiffswerft von F. Schichau. Zakład okrętowy posiadał sześć pochylni i pod względem możliwości budowy dużych statków należał do przodujących w Niemczech. W przedsiębiorstwach należących do firmy Schichaua budowano lokomotywy, ogromne okręty wojenne (pancerniki i krążowniki), pogłębiarki portowe, a także aparaturę dla cukrowni i maszyny do tartaków. Tuż przed I wojną światową armator Norddeutscher Lloyd zamówił w stoczni dwa rekordowej wielkości pasażerskie olbrzymy – legendarne transatlantyki „Columbus”.
Ślady działalności zakładów Schichaua wciąż daje się zauważyć w wielu miejscach, a jego postać przeszła do legendy. Artykuł stanowi opowieść o założycielu, jego spadkobiercach i przedsiębiorstwach przez nich prowadzonych. Starałem się przedstawić te aspekty działalności firmy, które uznać wypada za kluczowe. To szkic historyczny, przedstawiający losy ogromnego w swej skali przemysłowego przedsięwzięcia, które szczyt swego rozwoju osiągnęło na przełomie XIX i XX w. Było wizytówką Gdańska i miastem w mieście. Zagościło w literaturze i jest stałym elementem wyobraźni historycznej każdego, kto zajmuje się dziejami miasta.
"Restituta". Author’s family life meanders in Gdańsk and Pomerania
Authors: Cywiński Zbigniew 
Published: June 2021

On the centenary of Poland’s rebirth in 1918, I found the need to touch the life of Polish people in Prussia before WW1 and later – in Poland during the interwar period, in Nazi Germany (1939–1945), and in after­­‑war Poland since 1945; the place has been limited to the historical Pomerania, situated on the Vistula.
A general approach I replace by a brief description of some casual events concerning my own family that can be characteristic for the particular times. In this paper, such standing has been modestly related also to the milieu of chance and mischance in human life.
Squamous cell carcinoma pada anjing rescue
Authors: Pawitri Diah 
Published: June 2021

Anjing rescue adalah anjing yang diadopsi atau mendapatkan rumah baru dari pemilik sebelumnya yang tidak mengurus, tidak memberi perhatian, melakukan kekerasan fisik dan atau membiarkan anjingnya berkeliaran di jalan. Squamous cell carcinoma merupakan tumor kulit yang banyak ditemukan pada hewan kecil khususnya terlalu banyak terpapar sinar matahari. Seekor anjing Pitttbull di rescue dan di bawa berobat ke klinik karena adanya massa cauliflower pada skapula kiri. Hasil pemeriksaan fisik dan berbagai pertimbangan pemilik, dilakukan operasi tanpa pemeriksaan penunjang laboratorium darah dan radiografi. Pengangkatan jaringan tumor dilakukan melalui tindakan bedah dimana daerah sayatan dibuat margin 2-3 cm pada jaringan sehat di sekitar tumor, penutupan area bedah dengan teknik teknik skin flapping. Pemeriksaan histopatologi jaringan tumor untuk penegakan diagnosa dan hasilnya diidentifikasi sebagai jenis cutaneous lokal ekstensif epidermal nekrosis dengan hiperkeratosis, parakeratotik dan othokeratotik dengan intradermal multifokus carcinoma (Squamous cell carcinoma non keratin) dan stromal fibroplasia.
Role of Inflammatory Mediators in Endothelial Dysfunction of Umbilical Cord Vessels in Pregnant Women after Third-Trimester Nonprimary Cytomegaloviral Infection
Authors: Dorofienko N. N. , Andrievskaya I. A. , Ishutina N. A. 
Published: June 2021

Background. Endothelial cells are the site of productive replication, hematogenous spread and persistence for a variety of viruses, including cytomegalovirus, which play a critical role in the development of vascular complications associated with cytomegalovirus infection due to developing endothelial dysfunction.Aim: to reveal the role of inflammatory mediators (tumor necrosis factor alpha, interleukin-1β, interleukin-8) in the formation of umbilical cord vascular endothelial dysfunction in reactivation of latent cytomegalovirus infection in the third trimester of pregnancy.Material and methods. The standard method of solid-phase (“sandwich” variant) enzyme immunoassay was carried out to study pro-inflammatory cytokines (tumor necrosis factor alpha, interleukin-1β, -8), endothelin-1, nitrite anion in the blood of the umbilical cord of newborns from mothers who come through reactivation of latent cytomegalovirus infection in the third trimester of pregnancy. The work includes examination data of 78 newborns born at 38–40 weeks of gestation. Among them: 45 newborns were born by CMV-seropositive women with reactivation of latent cytomegalovirus infection in the third trimester of pregnancy (main group) and 33 – by CMV-seronegative women (control group). Umbilical vein blood serum was chosen as the material for the study.Results. In the blood of the umbilical vein of newborns from mothers with reactivation of latent cytomegalovirus infection in the third trimester of pregnancy, a high level of pro-inflammatory cytokines was detected: tumor necrosis factor alpha, interleukin-1β, interleukin-8 (p < 0.001) with a simultaneous increase in the content of endothelin-1 and nitrite anion (p < 0.001), compared with similar indicators for healthy newborns.Conclusion. Reactivation of latent cytomegalovirus infection in the third trimester of pregnancy is associated with the formation of a systemic fetal inflammatory response determined by a high concentration of inflammatory mediators (tumor necrosis factor alpha, interleukin-1β, interleukin-8) and an increase in vasoactive compounds (endothelin-1 and nitrite-anion) leading to the formation of dysfunction of the vascular endothelium of the umbilical cord.
Analysis of the Degree of Involvement of the Lower Limb Muscles in the Pathological Process in Adolescents with Idiopathic Scoliosis
Authors: Shchurova E. N. , Saifutdinov M. S. , Dolganova T. I. , Akhmedova M. A. , Gorbach A. P. 
Published: June 2021

Background. The problem of the effect of adolescent idiopathic scoliosis on the functional condition of the lower limb muscles is still highlighted insufficiently.Aim. Analysis of the degree of involvement of the lower limb muscles in the pathological process in adolescents with idiopathic scoliosis.Methods. A comparative analysis has been made on the results of examination of 209 adolescents: 25 adolescents with idiopathic scoliosis; 170 normal adolescents; 14 adolescents with congenital scoliosis. The moments of force ofthe lower limb muscles were evaluated using dynamometric stands. Electrophysiological characteristics of the lower limb muscles were registered by the method of global and stimulation electroneuromyography.Results. The decrease in the amplitude of voluntary EMG of the femoral muscles in adolescents with idiopathic and congenital scoliosis is accompanied by dropping the moments of force relative to the values of the control group. The leg muscles are characterized by the preservation of the values of force at the level of normal test subjects under the conditions of the reduced voluntary EMG of high frequency. The amplitude of the M-responses of the indicator muscles and the values of the excitation propagation velocity along the motor fibers were also preserved. There are no statistically significant correlations between the amount of the spine deformity, on the one hand, and the values of asymmetry of the characteristics of the muscles in adolescents with idiopathic scoliosis.Conclusion. In adolescents with idiopathic scoliosis the function of femoral muscles is decreased, and there is no relationship between the amount of the spine deformity and the values of asymmetry of the characteristics of the lower limb muscles. The similar character of muscle function changes in adolescents with idiopathic and congenital scoliosis can testify that the cause of the observed changes is not the disease etiology, but the insufficient level of motor activity.
Optimization of the Algorithm for Choosing the Surgical Treatment of Anterior Recurrent Instability of the Shoulder Joint
Authors: Chirkov N. N. , Nikolaev N. S. , Pashentsev Y. A. , Alekseeva A. V. , Yakovlev V. N. 
Published: June 2021

Introduction. Chronic recurrent instability of the shoulder joint is a frequent outcome of conservative treatment oftraumatic dislocation of the shoulder (2.8–30 % of cases). Preoperative examination largely determines the outcome of surgical treatment of this pathology.The aim of the study was to provide a clinical assessment of the developed algorithm for the surgical treatment of patients with recurrent anterior shoulder joint instability. Materials and methods. The results of treatment of 98 patients with recurrent anterior shoulder joint instability were studied. Preoperative examination included clinical tests, MRI or CT with calculation of bone loss. Fifty-six patients (57.1 %) underwent Bankart operation, 14 patients (14.3 %) – Latarjet operation. Twenty-three patients (23.5 %) underwent Bankart + Remplissage surgery, and 5 (5.1 %) – Latarjet + remplissage. The result was assessed on the ROWE scale.Results. Bone defects significant in the formation of instability (“glenoid off track”) were found in 19.4 % of patients, and “glenoid on track” – in 80.6 %. According to the proposed algorithm for treating patients with anterior recurrent instability of the shoulder joint, the “glenoid off track” state was an indication for Latarjet surgery. When “glenoid on track” was used, indications for Bankart operation were displayed. The remplissage procedure was indicated in case of the presence of a Hill-Sachs grade 3 defect or the presence of hyperelasticity of the tissues of the shoulder joint. The mean ROWE score for the entire group of patients before surgery was 41.5 ± 12.8 points, and 15 months after sur gery – 94.9 ± 3.4 points. Two recurrent dislocations were revealed, one of which was associated with repeated trauma, and the other – with an incorrect choice of stabilization technique. One complication (axillary nerve neuropathy) was observed, which was arrested conservatively.Conclusions. The proposed algorithm allowed us to obtain positive results in 97.9 % of cases.
The Value of Cystoscopy in the Assessment of Interstitial Cystitis/Bladder Pain Syndrome
Authors: Sholan R. F. 
Published: June 2021

Background. There are significant differences in the diagnosis of interstitial cystitis/painful bladder syndrome (IC/ BPS), in particular, controversy regarding the diagnostic role of cystoscopy or hydrodistension cystoscopy.The aim of the study was to evaluate the results of cystoscopy with hydrodistension in women with IC/BPS.Materials and methods. The study involved 126 women with IC/BPS, mean age – 46.7 ± 14.0 years. The duration of the disease was 6.0 ± 2.8 years. Questionnaires PUF, VAS, USS, and potassium test were used. Cystoscopy and urinary bladder hydrodistension were performed.Results. The sum of points on the PUF scale was 8.14 ± 1.76, on the VAS scale – 5.45 ± 0.93, on the USS scale – 2.63 ± 0.91. A positive potassium test was detected in 91.3 % of cases, the sensitivity of the test was 86.5 %, the specificity – 84.6 %. The anatomical bladder capacity was 308.0 ± 77.5 ml. The average indicator of maximum bladder filling in women with mild pain was higher than in moderate and severe pain by 30.9 % (p < 0.05) and 53.0 % (p < 0.01), respectively. In 11.9 % of cases, polyps were detected at the external opening of the urethra. During cystoscopy, diffuse mucosal bleeding was detected in 39.8 % of cases, diffuse submucosal bleeding – in 21.4 %, rare glomerulations – in 14.3 %, Gunner’s lesions in 12.7 % of cases. After hydrodistension, the changes were more often diffuse (n = 57). There was a significant relationship (r = –0.57, p < 0.01) between the maximum filling of the bladder and the degree of severity of mucosal abnormalities. The severity of changes in the mucous membrane of the bladder positively correlated with the sum of points on the PUF questionnaire (r = +0.61, p = 0.003), on the VAS questionnaire (r = +0.59, p = 0.008) and according to the USS questionnaire (r = +0.66, p = 0.005).Conclusion. Cystoscopy can be used to examine IC/BPS in accordance with the recommendations of international societies. The obtained data can help to improve the effectiveness of IC/PBS diagnostics.
Influence of Disorders of Fatty Acid Metabolism, Arterial Wall Hypoxia, and Intraplaque Hemorrhages on Lipid Accumulation in Atherosclerotic Vessels
Authors: Osipenko A. N. 
Published: June 2021

The review describes a number of competing views on the main causes of cholesterol accumulation in atherosclerotic vessels. On the one hand, unregulated cholesterol influx into arterial intima is primarily related to the increasing proportion of atherogenic lipoproteins in the lipoprotein spectrum of blood. On the other hand, the leading role in this process is assigned to the increased permeability of endothelium for atherogenic lipoproteins. The increased ability of arterial intima connective tissue to bind atherogenic blood lipoproteins is also considered to be the leading cause of cholesterol accumulation in the vascular wall. The key role in cholesterol accumulation is also assigned to unregulated (by a negative feedback mechanism) absorption of atherogenic lipoproteins by foam cells. It is suggested that the main cause of abundant cholesterol accumulation in atherosclerotic vessels is significant inflow of this lipid into the vascular wall during vasa vasorum hemorrhages.The article also provides arguments, according to which disorder of fatty acid metabolism in arterial wall cells can initiate accumulation of neutral lipids in them, contribute to the inflammation and negatively affect the mechanical conditions around the vasa vasorum in the arterial walls. As a result, the impact of pulse waves on the luminal surface of the arteries will lead to frequent hemorrhages of these microvessels. At the same time, adaptive-muscular intima hyperplasia, which develops in arterial channel areas subjected to high hemodynamic loads, causes local hypoxia in a vascular wall. As a result, arterial wall cells undergo even more severe lipid transformation. Hypoxia also stimulates vascularization of the arterial wall, which contributes to hemorrhages in it. With hemorrhages, free erythrocyte cholesterol penetrates into the forming atherosclerotic plaque, a part of this cholesterol forms cholesterol esters inside the arterial cells. The saturation of erythrocyte membranes with this lipid in conditions of hypercholesterolemia and atherogenic dyslipoproteinemia contributes to the process of cholesterol accumulation in arteries.
Pengembangan Buku Ajar Fisika Berbasis Problem Based Learning pada Materi Elastisitas dan Hukum Hooke
Authors: Harefa Dwi Putri , Gumay Ovilia Putri Utami 
Published: June 2021

Penelitian ini bertujuan untuk mengembangkan Buku Ajar Fisika Berbasis Problem Based Learning pada pokok bahasan Elastisitas dan Hukum Hooke yang valid, dan praktis. Masalah dalam penelitian ini adalah 1)Bagaimana kualitas buku ajar Fisika berbasis Problem Based Learning jika ditinjau dari segi kevalidan, dan kepraktisan, pada kelas XI SMA Negeri 2 Lubuklinggau? 2)Bagaimana mendesain dan mengembangkan buku ajar fisika berbasis Problem Based Learning yang memenuhi sasaran kevalidan, dan kepraktisan, pada kelas XI SMA Negeri 2 Lubuklinggau?. Subjek dalam penelitian ini adalah kelas XI MIA 2 yang terdiri dari 9 siswa yang diambil dengan teknik purposive sampling. Model pengembangan dalam penelitian ini mengacu terhadap model pengembangan dari sugiyono yang terdiri dari 1. Potensi dan masalah, 2.Pengumpulan data, 3.Desain produk, 4.Validasi desain, 5.Revisi desain, 6.Uji coba produk, 7.Revisi produk, 8.Uji coba pemakaian, 9.Revisi produk, 10.Produksi massal. Tetapi dalam penelitiannya hanya menggunakan 9 tahapan pengembangan saja. Pengumpulan data dilakukan dengan teknik angket respon siswa. Dan validasi terdiri dari 3 validasi ahli, validasi materi dengan penilaian 42 dalam kategori sangat baik, validasi bahasa dengan penilaian 18 dalam kategori baik, dan validasi media dengan penilaian 28 dalam kategori baik. Validasi yang dilakukan mendapatkan hasil dengan penilaian 88 dalam kategori baik. Respon siswa terhadap modul fisika berbasis Problem Based Learning dengan penilaian 330 dalam kategori sangat baik. Sehingga dapat dikatakan bahwa Buku Ajar fisika berbasis Problem Based Learning yang dikembangkan telah valid, dan praktis.
Uma videótica flusseriana para a coleção de videoarte The Refugee Memorial
Authors: Campos Ruy Cézar , Garcia Yuri , Inácio Thaís 
Published: June 2021

Vilém Flusser encarava o vídeo como uma ferramenta epistemológica que opera sem se reduzir ao logos da lógica, gestando uma “videótica” marcada pela capacidade de instaurar uma atmosfera dialógica, não linear e potencialmente multiplicadora de pontos de vista ao pensamento. Ao mesmo tempo, ele também refletia sobre os exilados, refugiados e imigrantes como naturais instauradores (pela própria demanda de hospitalidade que colocam para seus novos vizinhos) dessa atmosfera dialógica, suscitando problemas cujas soluções passam pela ética, política, técnicos e estética. Nesse sentido, desenvolvemos o artigo movimentando tais entendimentos de Flusser sobre vídeo e os “expelidos”, associando-os com reflexões resultantes de uma entrevista como curador do memorial de videoarte The Refugee Memorial, Wilfried Agricola de Cologne, e com um recorte de obras que integram a coleção.
Palavras-chave: Imigração. Refugiados. Videoarte.
ANALISA VALUASI EMITEN KARYA LISTED IDX
Authors: . M Aditya Ananda 
Published: June 2021

ABSTRACT
This study aims to analyze the stock valuation of construction issuers, especially BUMN Karya using data for the first quarter – third quarter of 2020 obtained from financial statements. The ratio used is the valuation ratio such as Price to Book Value and Price to Earning to Share. The solvency ratio used is the Debt to Equity Ratio and the market cap value. The three construction issuers that are the focus of the analysis are PT Waskita Karya (WSKT), Tbk, PT Wijaya Karya, Tbk (WIKA) and PT. Pembangunan Perumahan, Tbk (PTPP). From the results of the analysis obtained in the third quarter of 2020, WSKT has a value of PBV 0.84, PER -7.56, DER 3.87 with a Market Cap of 19.9T. WIKA has a value of PBV 1.00, PER 320.79, DER 2.80 and Market Cap 16.1T. while PTPP, has PBV 0.66, PER 358.82, DER 2.79, Market Cap 9.4T. among the three issuers, WSKT has a negative value due to having a corrected profit in the third quarter of 2020. While the lowest PBV is owned by PTPP while the highest DER is owned by WSKT.
Emigrazione, multiculturalità e psicoanalisi: il punto di vista di una psicoanalista
Authors: Grieve Patricia 
Published: June 2021

- Emigration and its consequences, present-day multi-cultural societies, confront us with many questions, as individuals, and in our psycho-analytic work with patients. From Psycho- analysis, we can observe how our encounter with different cultures refers us to the initial encounter with differences, at the base of psychic life, and to the first identifications and the unconscious personal myths that give narrative shape to the latter. In this respect, within the analytic situation, cultural differences affect the transference and the countertransference, particularly when patient and/or analyst belong to different cultures.Parole chiave: emigrazione, multiculturalismo, colpa, identità, scissione, altroKey words: Emigration, multiculturalism, guilt, identity, splitting, other