bluuebunny/crossref_metadata_2025_split huggingface dataset:
Abelian mirror symmetry of $$ \mathcal{N} $$ = (2, 2) boundary conditions
Authors: Okazaki Tadashi 
Published: March 2021

Abstract
We evaluate half-indices of $$ \mathcal{N} $$
N
= (2, 2) half-BPS boundary conditions in 3d $$ \mathcal{N} $$
N
= 4 supersymmetric Abelian gauge theories. We confirm that the Neumann boundary condition is dual to the generic Dirichlet boundary condition for its mirror theory as the half-indices perfectly match with each other. We find that a naive mirror symmetry between the exceptional Dirichlet boundary conditions defining the Verma modules of the quantum Coulomb and Higgs branch algebras does not always hold. The triangular matrix obtained from the elliptic stable envelope describes the precise mirror transformation of a collection of half-indices for the exceptional Dirichlet boundary conditions.
Functional a posteriori error estimates for boundary element methods
Authors: Kurz Stefan , Pauly Dirk , Praetorius Dirk , Repin Sergey , Sebastian Daniel 
Published: March 2021

AbstractFunctional error estimates are well-established tools for a posteriori error estimation and related adaptive mesh-refinement for the finite element method (FEM). The present work proposes a first functional error estimate for the boundary element method (BEM). One key feature is that the derived error estimates are independent of the BEM discretization and provide guaranteed lower and upper bounds for the unknown error. In particular, our analysis covers Galerkin BEM and the collocation method, what makes the approach of particular interest for scientific computations and engineering applications. Numerical experiments for the Laplace problem confirm the theoretical results.
Functional gastrointestinal disorders in children: agreement between Rome III and Rome IV diagnoses
Authors: Baaleman Desiree F. , Velasco-Benítez Carlos A. , Méndez-Guzmán Laura M. , Benninga Marc A. , Saps Miguel 
Published: March 2021

AbstractTo evaluate the agreement between the Rome III and Rome IV criteria in diagnosing pediatric functional gastrointestinal disorders (FGIDs), we conducted a prospective cohort study in a public school in Cali, Colombia. Children and adolescents between 11 and 18 years of age were given the Spanish version of the Questionnaire on Pediatric Functional Gastrointestinal Disorders Rome III version on day 0 and Rome IV version on day 2 (48 h later). The study protocol was completed by 135 children. Thirty-nine (28.9%) children were excluded because of not following the instructions of the questionnaire. The final analysis included data of 96 children (mean 15.2 years old, SD ± 1.7, 54% girls). Less children fulfilled the criteria for an FGID according to Rome IV compared to Rome III (40.6% vs 29.2%, p=0.063) resulting in a minimal agreement between the two criteria in diagnosing an FGID (kappa 0.34, agreement of 70%). The prevalence of functional constipation according to Rome IV was significantly lower compared to Rome III (13.5% vs 31.3%, p<0.001), whereas functional dyspepsia had a higher prevalence according to Rome IV than Rome III (11.5% vs 0%).Conclusion: We found an overall minimal agreement in diagnosing FGIDs according to Rome III and Rome IV criteria. This may be partly explained by the differences in diagnostic criteria. However, limitations with the use of questionnaires to measure prevalence have to be taken into account.

What is Known:• The Rome IV criteria replaced the previous Rome III criteria providing updated criteria to diagnose functional gastrointestinal disorders (FGIDs).• Differences found between Rome IV and historic Rome III FGID prevalence may have been affected by changes in prevalence over time or differences in sample characteristics.

What is New:• We found a minimal agreement between Rome III and Rome IV FGID diagnosis, especially in the diagnoses of functional constipation, irritable bowel syndrome, and functional dyspepsia.• The minimal agreement may be partly explained by changes in diagnostic criteria, but limitations with the use of questionnaires to measure prevalence have to be taken into account.
Cytotoxic effect of sodium hypochlorite (Lavanox 0.08%) and chlorhexidine gluconate (Irrisept 0.05%) on human osteoblasts
Authors: Böhle Sabrina , Röhner Eric , Zippelius Timo , Jacob Benjamin , Matziolis Georg , Rohe Sebastian 
Published: March 2021

Abstract
Purpose
Soft tissue, bone and joint infections are severe complications in orthopedic and traumatological surgery. Lavanox (0.08% NaOCl) and Irrisept (0.05% chlorhexidine gluconate, CHG) are industrially produced antiseptic solutions commonly used in infection treatment. Regarding this clinical indication, the microbicidal effect is often investigated, but toxicity to osteoblasts has rarely been examined. This is important to decide whether these solutions should be used in septic situations in which bone healing must take place. The hypothesis of the present study is that NaOCl and CHG are cytotoxic to osteoblasts even after a short exposure time.

Methods
Human osteoblasts were isolated from donors with osteoarthritis during total knee and hip arthroplasty. Cells were cultivated and treated with both antiseptic solutions for 2, 5 and 10 min in different dilutions. Toxicity was quantified by counting cells, lactate dehydrogenase (LDH) expression, spectrophotometric quantification via XTT assay and FDA/PI fluorescence microscopy.

Results
Analyzing viable cells after treatment with both antiseptics showed a significant decrease in viable cells through LDH expression test, XTT assay, fluorescence microscopy and light microscopy, depending on concentration. The time dependence showed a trend to more cell death at longer exposure times, without significance.

Conclusion
Toxic effects on osteoblasts were shown after treatment with 0.08% NaOCl and 0.05% CHG after an exposure time of 2 min which also was concentration dependent. There was no difference in cytotoxicity between both antiseptics. In conclusion, these antiseptic solutions may be used with caution in situations requiring bone healing.
Trial registration number
Local ethics committee registration number: 5176–07/16
Loops and Building Blocks: a Knowledge co-Production Framework for Equitable Urban Health
Authors: Audia Camilla , Berkhout Frans , Owusu George , Quayyum Zahidul , Agyei-Mensah Samuel 
Published: March 2021

AbstractThis paper sets out a structured process for the co-production of knowledge between researchers and societal partners and illustrates its application in an urban health equity project in Accra, Ghana. The main insight of this approach is that research and knowledge co-production is always partial, both in the sense of being incomplete, as well as being circumscribed by the interests of participating researchers and societal partners. A second insight is that project-bound societal engagement takes place in a broader context of public and policy debate. The approach to co-production described here is formed of three recursive processes: co-designing, co-analysing, and co-creating knowledge. These ‘co-production loops’ are themselves iterative, each representing a stage of knowledge production. Each loop is operationalized through a series of research and engagement practices, which we call building blocks. Building blocks are activities and interaction-based methods aimed at bringing together a range of participants involved in joint knowledge production. In practice, recursive iterations within loops may be limited due of constraints on time, resources, or attention. We suggest that co-production loops and building blocks are deployed flexibly.
Kurze Zündschnur: Ärger – Wut – Aggression
Authors: Schröter Romy , Lambert Martin , Karow Anne , Lüdecke Daniel , Gallinat Jürgen , Briken Peer 
Published: March 2021

ZusammenfassungVerschiedene psychische Erkrankungen, wie Persönlichkeitsstörungen, sind mit einem Risiko für gewalttätiges Verhalten assoziiert. Dieses Risiko wird jedoch nur selten durch gezielte psychotherapeutische Interventionen adressiert. Vielmehr werden im psychiatrischen Setting aggressive und impulsive Patienten oftmals isoliert und auf geschützten Stationen aufgenommen. Dies kann beispielsweise durch Stigmatisierung und das Schüren von Ängsten aggressives Verhalten auch begünstigen. Aufgrund von aggressivem Verhalten kommt es zudem häufig zu kurzfristigen disziplinarischen Entlassungen oder konflikthaften Eskalationen im Stationsalltag. Insgesamt besteht sowohl im stationären als auch im ambulanten Setting eine Versorgungslücke. Es mangelt an spezifischen psychotherapeutischen Angeboten, die Patienten Strategien zur Bewältigung von aggressivem Verhalten vermitteln können.Ein Patientenkollektiv, an dem diese Versorgungslücke deutlich wird, sind Männer mit Persönlichkeitsstörungen. Speziell für diese Patienten wurde ein gruppenpsychotherapeutisches Konzept entwickelt, welches hier vorgestellt werden soll: Die Ärger-Wut-Aggressions(AeWA)-Gruppe. Das Konzept nimmt männliche Patienten mit Störung der Impulskontrolle in den Blick. Dabei wird auf emotionale und entwicklungspsychologische Kernbedürfnisse eingegangen und eine Vielzahl an kognitiven, behavioralen und emotionsfokussierten Techniken vermittelt. Diese sollen eine funktionale Emotionsregulation fördern und gleichzeitig das Auftreten von aggressiven Verhaltensweisen und das damit verbundene Risiko für Straffälligkeit verringern.
A TRiP Through the Roles of Transient Receptor Potential Cation Channels in Type 2 Upper Airway Inflammation
Authors: Backaert Wout , Steelant Brecht , Hellings Peter W. , Talavera Karel , Van Gerven Laura 
Published: March 2021

Abstract
Purpose of Review
Despite their high prevalence, the pathophysiology of allergic rhinitis (AR) and chronic rhinosinusitis (CRS) remains unclear. Recently, transient receptor potential (TRP) cation channels emerged as important players in type 2 upper airway inflammatory disorders. In this review, we aim to discuss known and yet to be explored roles of TRP channels in the pathophysiology of AR and CRS with nasal polyps.

Recent Findings
TRP channels participate in a plethora of cellular functions and are expressed on T cells, mast cells, respiratory epithelial cells, and sensory neurons of the upper airways. In chronic upper airway inflammation, TRP vanilloid 1 is mostly studied in relation to nasal hyperreactivity. Several other TRP channels such as TRP vanilloid 4, TRP ankyrin 1, TRP melastatin channels, and TRP canonical channels also have important functions, rendering them potential targets for therapy.

Summary
The role of TRP channels in type 2 inflammatory upper airway diseases is steadily being uncovered and increasingly recognized. Modulation of TRP channels may offer therapeutic perspectives.
What if Social Robots Look for Productive Engagement?
Authors: Nasir Jauwairia , Bruno Barbara , Chetouani Mohamed , Dillenbourg Pierre 
Published: March 2021

AbstractIn educational HRI, it is generally believed that a robots behavior has a direct effect on the engagement of a user with the robot, the task at hand and also their partner in case of a collaborative activity. Increasing this engagement is then held responsible for increased learning and productivity. The state of the art usually investigates the relationship between the behaviors of the robot and the engagement state of the user while assuming a linear relationship between engagement and the end goal: learning. However, is it correct to assume that to maximise learning, one needs to maximise engagement? Furthermore, conventional supervised models of engagement require human annotators to get labels. This is not only laborious but also introduces further subjectivity in an already subjective construct of engagement. Can we have machine-learning models for engagement detection where annotations do not rely on human annotators? Looking deeper at the behavioral patterns and the learning outcomes and a performance metric in a multi-modal data set collected in an educational human–human–robot setup with 68 students, we observe a hidden link that we term as Productive Engagement. We theorize a robot incorporating this knowledge will (1) distinguish teams based on engagement that is conducive of learning; and (2) adopt behaviors that eventually lead the users to increased learning by means of being productively engaged. Furthermore, this seminal link paves way for machine-learning models in educational HRI with automatic labelling based on the data.
Professionalism revisited during the pandemics of our time: COVID-19 and racism
Authors: Zaidi Zareen , Razack Saleem , Kumagai Arno K. 
Published: March 2021

In this article the authors review the current-day definition of professionalism through the lens of the two ongoing pandemics: COVID-19 and racism. The pandemics have led to contemporary practice-related questions, such as: does professionalism entail that health care providers (HCP) be compelled to treat patients without PPE or if patients refuse to wear masks? And what role do HCP play in society when confronted with glaring health disparities and police brutality? The authors propose using care ethics as a theory to view professionalism, as it takes into account broadly encompassing relationships between HCP and society, history and context. Professionalism viewed through a care ethics lens would require professionalism definitions to be expanded to allow for interventions, i.e., not just refrain from doing harm but actively interfere or take action if wrong is being witnessed. Principles related to the primacy of patient welfare need to be re-addressed to prevent systematic self-sacrifice which results in harm to HCP and burnout. Mature care should be a characteristic of professionalism ensuring that HCP care for the sick but be practically wise, highlighting the importance of balancing too little and too much care for self and others. Professionalism needs to be viewed as a bi-directional relational exchange, with society demonstrating solidarity with those providing care. Additionally, given the scale of health disparities, simply stating that HCP need to work towards social justice oversimplifies the problem.
A dominated convergence theorem for Eisenstein series
Authors: Franke Johann 
Published: March 2021

AbstractBased on the new approach to modular forms presented in [6] that uses rational functions, we prove a dominated convergence theorem for certain modular forms in the Eisenstein space. It states that certain rearrangements of the Fourier series will converge very fast near the cusp $$\tau = 0$$

τ
=
0

. As an application, we consider L-functions associated to products of Eisenstein series and present natural generalized Dirichlet series representations that converge in an expanded half plane.
Recoverable autonomous sonde for subglacial lake exploration: electronic control system design
Authors: Peng Shilin , Jiang Xiao , Tang Yongzhen , Li Chong , Li Xiaodong , Huang Shengmiao , Zhu Tianxin , Shi Jianguang , Sun Youhong , Talalay Pavel , Fan Xiaopeng , Zhang Nan , Li Bing , Gong Da , Yu Haibin 
Published: March 2021

AbstractSubglacial lake exploration is of great interest to the science community. RECoverable Autonomous Sonde (RECAS) provides an exploration tool to measure and sample subglacial lake environments while the subglacial lake remains isolated from the glacier surface and atmosphere. This paper presents an electronic control system design of 200 m prototype of RECAS. The proposed electronic control system consists of a surface system, a downhole control system, and a power transfer and communication system. The downhole control system is the core element of RECAS, and is responsible for sonde status monitoring, sonde motion control, subglacial water sampling and in situ analysis. A custom RS485 temperature sensor was developed to cater for the limited size and depth requirements of the system. We adopted a humidity-based measurement to monitor for a housing leak. This condition is because standard leak detection monitoring of water conductivity may be inapplicable to pure ice in Antarctica. A water sampler control board was designed to control the samplers and monitor the on/off state. A high-definition camera system with built-in storage and self-heating ability was designed to perform the video recording in the subglacial lake. The proposed electronic control system is proven effective after a series of tests.
Philosophy as Synchronic History
Authors: STOLJAR DANIEL 
Published: March 2021

AbstractBernard Williams argues that philosophy is in some deep way akin to history. This article is a novel exploration and defense of the Williams thesis (as I call it)—though in a way anathema to Williams himself. The key idea is to apply a central moral from what is sometimes called the analytic philosophy of history of the 1960s to the philosophy of philosophy of today, namely, the separation of explanation and laws. I suggest that an account of causal explanation offered by David Lewis may be modified to bring out the way in which this moral applies to philosophy, and so to defend the Williams thesis. I discuss in detail the consequences of the thesis for the issue of philosophical progress and note also several further implications: for the larger context of contemporary metaphilosophy, for the relation of philosophy to other subjects, and for explaining, or explaining away, the belief that success in philosophy requires a field-specific ability or brilliance.
Moscow University’s field station in the Khibiny Mountains, Russian Arctic: A 70-year history to the present day
Authors: Vikulina M.A. , Vashchalova T.V. , Tutubalina O.V. , Rees W.G. , Zaika Y.V. 
Published: March 2021

Abstract
The Khibiny Educational and Scientific Station (KESS) of the Faculty of Geography, M.V. Lomonosov Moscow State University (MSU), was founded in 1948. It is one of the oldest stations of the MSU Faculty of Geography and the only one located north of the Arctic Circle. It is also one of the oldest continuously operating arctic field stations in the world. For more than 70 years, the research station has fostered scientific and international collaboration. Science and education carried out at the station have always gone hand in hand and the research results have been both theoretical and practical. Many generations of Russian geographers owe their successful careers to the research activities at the Khibiny station. Nowadays, it is one of the two major student training bases for the Faculty of Geography as well as a focal point of many national and international research projects, including the International Network for Terrestrial Research and Monitoring in the Arctic (INTERACT) network.
The influence of comorbid depression and overweight status on peripheral inflammation and cortisol levels
Authors: McLaughlin Anna P. , Nikkheslat Naghmeh , Hastings Caitlin , Nettis Maria A. , Kose Melisa , Worrell Courtney , Zajkowska Zuzanna , Mariani Nicole , Enache Daniela , Lombardo Giulia , Pointon Linda ,   NIMA Consortium, Cowen Philip , Cavanagh Jonathan , Harrison Neil , Bullmore Edward , Pariante Carmine M. , Mondelli Valeria 
Published: March 2021

AbstractBackgroundDepression and overweight are each associated with abnormal immune system activation. We sought to disentangle the extent to which depressive symptoms and overweight status contributed to increased inflammation and abnormal cortisol levels.MethodsParticipants were recruited through the Wellcome Trust NIMA Consortium. The sample of 216 participants consisted of 69 overweight patients with depression; 35 overweight controls; 55 normal-weight patients with depression and 57 normal-weight controls. Peripheral inflammation was measured as high-sensitivity C-Reactive Protein (hsCRP) in serum. Salivary cortisol was collected at multiple points throughout the day to measure cortisol awakening response and diurnal cortisol levels.ResultsOverweight patients with depression had significantly higher hsCRP compared with overweight controls (p = 0.042), normal-weight depressed patients (p < 0.001) and normal-weight controls (p < 0.001), after controlling for age and gender. Multivariable logistic regression showed that comorbid depression and overweight significantly increased the risk of clinically elevated hsCRP levels ⩾3 mg/L (OR 2.44, 1.28–3.94). In a separate multivariable logistic regression model, overweight status contributed most to the risk of having hsCRP levels ⩾3 mg/L (OR 1.52, 0.7–2.41), while depression also contributed a significant risk (OR 1.09, 0.27–2). There were no significant differences between groups in cortisol awakening response and diurnal cortisol levels.ConclusionComorbid depression and overweight status are associated with increased hsCRP, and the coexistence of these conditions amplified the risk of clinically elevated hsCRP levels. Overweight status contributed most to the risk of clinically elevated hsCRP levels, but depression also contributed to a significant risk. We observed no differences in cortisol levels between groups.
Gendered leisure time-use and its impact on cognitive function among older adults in rural China
Authors: Liu Huijun , Pei Yaolin , Wu Bei 
Published: March 2021

AbstractIncreasing evidence has shown that an active, socially engaged lifestyle in leisure time might protect older adults against the decline of cognitive function. It remains unclear, however, which types of leisure activities are more beneficial to maintain cognitive function, and whether there are gender differences in the association between leisure activities and cognitive function. We used a two-wave of panel data from 1,018 older adults aged 60 and older in rural China to examine the lag effects of different types of leisure activities on cognitive functioning and to identify the gender differences in their impacts on cognition in rural China. Ordinary least-squares regression models showed that high physical activities were associated with better cognitive function. High intensity of cognitive activities and engaging in physical activities have a protective effect on cognitive function among older men rather than older women. Further, we found that cognitive activities had a stronger effect on cognitive function among older men than older women. It is important to consider gender-specific intervention in leisure activities to maintain cognitive function among older adults.
New insights inCercopithecinaespermatozoa
Authors: Martinez Guillaume , Garcia Cécile , Francois-Brazier Céline , Laidebeure Sylvie , Leclerc Antoine , Lecu Alexis , Mulot Baptiste , Petit Thierry , Quintard Benoit , Brouillet Sophie , Arnoult Christophe , Coutton Charles , Lacoste Romain 
Published: March 2021

SummarySperm morphometric and morphologic data have been shown to represent useful tools for monitoring fertility, improving assisted reproduction techniques and conservation of genetic material as well as detecting inbreeding of endangered primates. We provide here for the first time sperm morphologic and morphometric data fromCercopithecus neglectus,Cercopithecus cephus,Papio papioand critically endangeredCercopithecus roloway, as well as comparative data from otherCercopithecinaespecies, i.e.Allochrocebus lhoesti,Mandrillus sphinxandPapio anubis. Following collection from the epididymis, spermatozoa were measured for each species for the following parameters: head length, head width, head perimeter, head area, midpiece length and total flagellum length, and the head volume, ellipticity, elongation, roughness and regularity were then calculated. Our data are consistent with both the general morphology and the morphometric proportions ofCercopithecinaesperm. Some specificities were observed, withC. cephusdisplaying a narrow head (width = 2.76 ± 0.26 µM) andC. rolowaydisplaying a short midpiece (6.65 ± 0.61 µM). This data set represents an important contribution, especially forCercopithecus roloway, one of the most endangered monkeys in the world, and further data on additional specimens coupled to data on mating systems and reproductive ecology should allow a better understanding of the mechanisms underlying these morphological differences across primate species.