bluuebunny/crossref_metadata_2025_split huggingface dataset:
Les comédiennes-ouvrières à Hénin-Beaumont (2007-2019) : récit de la fabrique d’une pièce de théâtre engagée pour les Samsonite
Authors: Gallot Fanny , Ibos Caroline 
Published: June 2021

En 2007, l’usine Samsonite située à Hénin-Beaumont est liquidée à la suite d’une faillite frauduleuse et deux cent cinquante salariés, principalement des ouvrières, perdent leur emploi. À côté de la bataille judiciaire et pour continuer la lutte, sept d’entre elles participent à l’écriture et jouent une pièce de théâtre sur l’histoire des Samsonite, On n’est pas que des valises ! . Issu d’un travail d’enquête mené par une historienne et une sociologue, l’article revient sur la fabrique d’une pièce de théâtre engagée pour envisager le jeu complexe de l’emboîtement des récits dans la construction mémorielle, à partir de l’analyse des sources orales collectées auprès des « comédiennes-ouvrières », notamment pour éclairer ce que la fiction théâtrale fige, trouble ou laisse de côté.
La sécurité affective et le bien-être des enfants confiés : une analyse du vécu du placement à la lumière de la théorie de l’attachement
Authors: Toussaint Emmanuelle , Bacro Fabien 
Published: June 2021

Cette étude s’intéresse au moment où le placement prend effet en prenant appui sur les témoignages des enfants eux-mêmes. Elle a pour objectifs de décrire les émotions éprouvées par les enfants au moment de la séparation et de l’accueil dans un nouveau lieu de vie telles qu’ils peuvent eux-mêmes les rapporter, et d’explorer les stratégies adaptatives mises en œuvre par les enfants pour faire face à la séparation. 15 enfants âgés de 10 à 18 ans ont été interrogés dans le cadre d’entretiens semi-directifs. Les données ont été traitées quantitativement et qualitativement avec le logiciel d’analyse sémantique Tropes et avec le scénario « Emotaix », qui permet de recenser et de catégoriser le lexique émotionnel présent dans les récits. L’analyse des résultats montre que les enfants ressentent majoritairement des émotions à valence négative au moment du placement. Les émotions les plus saillantes s’articulent autour de quatre catégories : l’anxiété, le mal-être et le trouble, le bien-être étant proportionnellement beaucoup moins représenté. À la lumière de la théorie de l’attachement, cette étude permet d’améliorer notre compréhension de l’expérience faite par les enfants au moment où le placement prend effet et de formuler des préconisations visant à mieux les accompagner.
Les enjeux psychiques de la transplantation rénale en unité de néphrologie pédiatrique
Authors: Gourdon Bénédicte , Godron-Dubrasquet Astrid , Lucats Florence , Cochin Ninon 
Published: June 2021

La transplantation rénale en service de néphrologie pédiatrique questionne autant la dimension physique que psychique de l’enfant greffé. Nous regarderons dans cet article les problématiques psychiques soulevées par l’insuffisance rénale chronique et terminale, la question du don ainsi que les problématiques identitaires mises en jeu. L’enfant est un être en mouvement, en évolution. Quel est l’impact de la greffe rénale sur son évolution ? Ses représentations ? Son devenir ?
Approche systémique en pédopsychiatrie : responsabiliser l’entourage sans culpabiliser
Authors: Carneiro Claudio 
Published: June 2021

« Est-ce qu’on fait quelque chose de faux ou est-ce qu’il/elle a un problème ? » On peut penser que tous les parents qui consultent pour leur enfant dans un service de pédopsychiatrie se posent cette question de façon plus ou moins explicite. Tout le défi pour le thérapeute systémique consiste alors à essayer de mobiliser les parents, de les impliquer dans le suivi, sans les culpabiliser en les faisant se sentir comme étant la cause du problème. Cet article propose une réflexion sur comment responsabiliser l’entourage du patient sans culpabiliser. La question de la différence entre les notions de responsabilité et de culpabilité sera notamment abordée, puis l’intervention intégrative de la connotation positive responsabilisante sera présentée et les implications sur les settings thérapeutiques seront discutées
Intraspecific density effect on growth of Marphysa “sp.” Juveniles
Authors: Garcês João Pedro , Pousão-Ferreira Pedro 
Published: June 2021

There is growing demand for the territorial tube-building genus Marphysa (Eunicidae: Polychaete), commonly known in Portugal as “goose”, for use as fishing bait, and it is being harvested all around the world for that purpose. Effects of intraspecific density on juvenile growth were studied over a four-month period in laboratory facilities. Three polychaete densities (low, 50 worms; medium, 150 worms; and high, 250 worms) were used in a 0.25 m2 aquarium containing sandy sediment and recirculating water. Total length, dry weight and number of segments were recorded for 60% of the initial population. All polychaetes were also counted to determine mortality rate and territorial behaviour through the existence of body lesions and broken and regenerating posterior segments. The results obtained in this study showed that density had a significant effect (p<0.001) on growth rates in any of the densities studied and that growth was significantly higher at lower densities (p<0.001). For all density levels, estimated daily growth was higher in the first month, decreasing progressively over time. The high aggressiveness and territorial behaviour of Marphysa “sp.” juveniles, well evidenced by the highest mortality (35%) under high density and by the presence of worms with lesions under low density (30%) observed in the first month, suggests that territoriality is probably the main factor involved in the organization and spatial arrangements of individuals within a population. Marphysa juveniles probably compete for burrow space. The results reveal that Marphysa juveniles have a very territorial and aggressive behaviour that should be considered if the species is used for aquaculture production. Additional studies are required to determine the density effects for different developmental stages.
Engagement civique des électeurs au seuil de l’âge adulte en région parisienne
Authors: Allen LaRue , Berg Juliette , Bang Hee Jin 
Published: June 2021

Pour favoriser la participation des jeunes à la vie civique, il nous faut comprendre les facteurs individuels et contextuels qui déterminent leur engagement dans les domaines civique et politique. Cette étude illustre les rapports entre les caractéristiques personnelles des jeunes, le contexte proximal et national dans lequel ils évoluent et leur participation à la vie politique. L’article, qui utilise les données extraites d’une enquête effectuée auprès de 632 élèves de quatre lycées à forte diversité ethnique de la région parisienne, se fonde essentiellement sur celles provenant des 245 participants en âge de voter. Nous y examinons les facteurs relevant du contexte individuel, proximal et national susceptible d’influencer l’engagement des jeunes en utilisant trois indices de participation politique et civique : l’engagement dans des activités politiques, la participation à des mouvements sociaux et la participation non conventionnelle. Il ressort des résultats que les jeunes qui possèdent de plus grandes connaissances dans le domaine politique ont plus de chances de participer à des activités politiques conventionnelles. Les variations dans deux des trois indices s’expliquent aussi par le genre et l’appartenance ethnique. Le rapport étroit révélé entre les contextes de l’école et des pairs et chaque type d’engagement souligne l’importance de l’éducation civique, de l’efficacité collective à l’école et d’un climat de classe ouvert favorisant la discussion dans la promotion de la participation politique des jeunes adultes.
Following Transplantation for Acute Myelogenous Leukemia, Donor KIR Cen B02 Better Protects against Relapse than KIR Cen B01
Authors: Guethlein Lisbeth A. , Beyzaie Niassan , Nemat-Gorgani Neda , Wang Tao , Ramesh Vidhyalakshmi , Marin Wesley M. , Hollenbach Jill A. , Schetelig Johannes , Spellman Stephen R. , Marsh Steven G. E. , Cooley Sarah , Weisdorf Daniel J. , Norman Paul J. , Miller Jeffrey S. , Parham Peter 
Published: June 2021

Abstract
In the treatment of acute myelogenous leukemia with allogeneic hematopoietic cell transplantation, we previously demonstrated that there is a greater protection from relapse of leukemia when the hematopoietic cell transplantation donor has either the Cen B/B KIR genotype or a genotype having two or more KIR B gene segments. In those earlier analyses, KIR genotyping could only be assessed at the low resolution of gene presence or absence. To give the analysis greater depth, we developed high-resolution KIR sequence-based typing that defines all the KIR alleles and distinguishes the expressed alleles from those that are not expressed. We now describe and analyze high-resolution KIR genotypes for 890 donors of this human transplant cohort. Cen B01 and Cen B02 are the common CenB haplotypes, with Cen B02 having evolved from Cen B01 by deletion of the KIR2DL5, 2DS3/5, 2DP1, and 2DL1 genes. We observed a consistent trend for Cen B02 to provide stronger protection against relapse than Cen B01. This correlation indicates that protection depends on the donor having inhibitory KIR2DL2 and/or activating KIR2DS2, and is enhanced by the donor lacking inhibitory KIR2DL1, 2DL3, and 3DL1. High-resolution KIR typing has allowed us to compare the strength of the interactions between the recipient’s HLA class I and the KIR expressed by the donor-derived NK cells and T cells, but no clinically significant interactions were observed. The trend observed between donor Cen B02 and reduced relapse of leukemia points to the value of studying ever larger transplant cohorts.
Synergistic effect of flavonoids combined with antivenom on neutralisation of Naja naja venom
Authors: Raghavan Srimathi , Jayaraman Gurunathan 
Published: June 2021

Objective:
To evaluate the neutralizing effects of flavonoids on snake venom toxicity by stand-alone and combinatorial approaches.

Methods:
Synthetic flavonoids were assessed, either individually or in combination with antivenom, for their neutralization of phospholipase A2 (PLA2), protease, antioxidant (DPPH) assay and hemotoxic activity. Molecular docking studies were performed to understand possible binding of flavonoids with Naja naja venom PLA2. In vivo studies were carried out to confirm the neutralisation effects using a mouse model. Moreover, inhibition of PLA2 was monitored using combinatorial approaches.

Results:
Among the flavonoids used, quercetin and naringenin inhibited PLA2 (56% and 45%), protease (71% and 64%), DPPH scavenging (69.0% and 77.5%) and hemotoxic (70%) activities. Molecular docking studies indicated that the flavonoids bind to the substrate-binding site of PLA2 (Cys44 and Tyr63). In vivo studies showed a reduction in the venom toxicity level in the presence of naringenin. Additionally, combinatorial studies using the mixture of flavonoid and anti-venom revealed the possibility of synergistic effect (up to 32% enhancement) in neutralising the venom enzymes.

Conclusions:
These flavonoids can be used as additives for the treatment of snake bites, which may exert synergistic effects in combination with antivenom and decrease the post-therapeutic effects caused by excessive use of antivenom.
Anti-tumor activity of rice bran hydrolysates on migration, invasion and angiogenesis
Authors: Phusrisom Suphanthip , Senggunprai Laddawan , Prawan Auemduan , Kongpetch Sarinya , Kukongviriyapan Upa , Thawornchinsombut Supawan , Siriamornpun Sirithon , Chumroenphat Theeraphan , Changsri Ronnachai , Kukongviriyapan Veerapol 
Published: June 2021

Objective:
To investigate anti-tumor effect of rice bran hydrolysates (RBH) on proliferation, migration, invasion, and angiogenesis of cholangiocarcinoma (CCA) cells, and elucidate the underlying mechanisms.

Methods:
RBH was prepared from Tubtim Chumprae rice (Oryza sativa L.) by hydrothermolysis followed by protease digestion. Phenolic content in RBH was analyzed by high-performance liquid chromatography. Human CCA cells, KKU-156, KKU-452, and KKU-100, were used to study the effects of RBH on proliferation, migration, invasion, and adhesion by wound healing, Transwell chamber, and fibronectin cell adhesion assays. Angiogenesis was evaluated using human umbilical vein endothelial cells. Proteins associated with cancer progression were analyzed by immunobloting assays.

Results:
RBH contained carbohydrates, proteins, lipids, and various phenolic compounds and flavonoids. RBH did not inhibit CCA proliferation, but strongly suppressed migration, invasion, adhesion of CCA cells, and the formation of tube-like capillary structures of human umbilical vein endothelial cells. Moreover, RBH down-regulated phosphorylation of FAK, PI3K, and Akt, suppressed NF-κB nuclear translocation, decreased the expression of ICAM-1, vimentin and vascular endothelium growth factor (VEGF), and increased the expression of E-cadherin.

Conclusions:
RBH suppresses CCA cell migration and invasion and decreases expression of proteins involved in cancer metastasis. RBH is a potential food supplement for cancer prevention.
Coronaviruses in pregnant women in Saudi Arabia
Authors: Barry Mazin , Barry Magdoleen A. 
Published: June 2021

Objective:
To compare the effects of coronaviruses, such as Middle East respiratory syndrome coronavirus (MERS-CoV) or coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), on pregnant women in Saudi Arabia, and to understand the disease dynamics of these coronaviruses so as to konw how to provide care and management of infected pregnant women and infants.

Methods:
We conducted a systematic review of all published papers on MERS-CoV and SARS-CoV-2 infections in pregnant women in Saudi Arabia to identify knowledge gaps. Inclusion and exclusion criteria were based on the PRISMA system. The search included all papers which were published between September 1, 2012 and November 29, 2020 on pregnant women with MERS-CoV and/ or COVID-19 in Saudi Arabia. Of 26 papers screened, five were included in the analysis.

Results:
A total of 11 pregnant women with MERS-CoV and four with COVID-19 were reported in Saudi Arabia in the medical literature during the review period. The mean ages of the women were 33 and 31 years old for MERS-CoV and COVID-19, respectively. Maternal and fetal mortality in cases of MERS-CoV were 35% and 30%, respectively, while no maternal or fetal mortalities were reported in COVID-19 cases.

Conclusions:
Very limited data has emerged from Saudi Arabia on pregnant women MERS-CoV and COVID-19. With such high mortality observed with MERS-CoV compared to COVID-19, there is a need for greater reporting of cases to truly grasp the extent of these infections in pregnant women in a country where both coronaviruses are circulating.
Vitamin E supplementation may negatively affect preimplantation development and mitochondrial ultrastructure of vitrified murine embryos
Authors: Sarbandi Mimi-Sophia , Noor Khan Nor-Ashikin Mohamed Noor , Rahman Nor-Shahida Abdul , Eshak Zolkapli , Abdullah Fathiah , Malek Mastura Abd , Kamal Aqila-Akmal Mohammad 
Published: June 2021

Objective:
To observe the effects of vitamin E on post-vitrification preimplantation development, gross morphology as well as mitochondrial distribution and ultrastructure.

Methods:
Twenty-four female C57BL/6NTac mice, aged 12-16 weeks, were randomly divided into four groups. Group A did not receive any treatment and served as the control group. Group B was treated with corn oil stripped of tocopherols and served as the vehicle group. Group C was treated with 60 mg/kg body weight of tocotrienol-rich-fraction with corn oil stripped of tocopherols. Group D was treated with 60 mg/kg body weight of alpha-tocopherol with corn oil stripped of tocopherols. All treatments were administered orally for 7 consecutive days. After superovulation and mating with fertile males, 2-cell stage embryos were harvested for vitrification. Post vitrification development in vitro, gross morphology and ultrastructure were compared between groups.

Results:
The number of 2 and 8-cell embryo, and blastocysts in the treatment and control groups were not significantly different (P>0.05). Following vitrification, all 2-cell embryos had equal-sized blastomeres and intact zona pellucida. Mitochondrial aggregation toward the perinuclear region was seen in all of the treatment groups. Both groups C and D had vacuolated mitochondria, which was reflected in the trend of preimplantation development reduction.

Conclusions:
Vitamin E supplementation of 60 mg/kg body weight does not improve the viability of healthy embryos according to this study. As a result, the most effective dose of vitamin E supplementation may be determined by the initial quality of the embryos.
Comparative Evaluation of the Lateral Throat Form and the Border Extension of Mandibular Complete Denture in the Distolingual Region in Gandhinagar District
Authors: Shah Dipti S , Vaishnav Kalpesh , Patel Pankaj , Joshi Ravi , Sharma Khushboo , Patel Zalak 
Published: June 2021

Introduction:
Lateral throat form plays an important role in the success of lower complete denture as it affects its retention and stability. The length and thickness of lower dentures should be properly established in this region. Aim of this study is to evaluate the difference in the extension of lateral throat form between the patient's mouth and lower dentures.

Materials and Methods:
The lateral throat form was classified according to Neil's classification into Class I, Class II and Class III. The length of the lateral throat form was measured in the patient's mouth and in lower dentures with the help of UNC periodontal probe, and a comparison was made between them.

Results:
Among all the patients in this study, Neil's Class I lateral throat form was 53%, Class II was 37% and Class III was 10%. The average variation between the extent of lateral throat form intraorally and in lower denture at the anterior edge of the retromolar pad was 1.7 ± 1.75 mm in the right side and 2.5 ± 2.00 mm in the left side, whereas at the posterior edge of retromolar pad, it was 2.23 ± 1.92 mm in the right side and 3.06 ± 2.25 mm in the left side.

Conclusions:
The proportion of Neil's Class I was the highest followed by Class II and Class III was the lowest. The difference between the length of lateral throat form in the patient's mouth and in lower denture was statistically significant (P < 0.05).
Effect of Intake of Hypocaloric Diet and Low-Fat Dairy Food on Biomarkers of Weight Gain among Working Women in Banaras Hindu University, Varanasi, India
Authors: Upasana  , Pandey Vivek , Chakravarty Archana , Tripathi Yamini Bhusan , Gupta Kailash Kumar 
Published: June 2021

Background:
The rise in overweight and obesity is a major public health problem in today's era. The main reasons are nutrition transition, urbanisation, westernisation, sedentary lifestyle and lack of physical activity. These interlinkage leads to modifications in physiological response via adipocytokines which are closely related to degenerative diseases.

Objectives:
The study aims to find out the percent change in biomarkers of weight gain among overweight and obese working women (respondents).

Methodology:
By purposive sampling technique, 32 respondents were selected and data were collected by interview schedule method. All respondents underwent 6 months of intervention programme i.e., dietary guidelines of following the hypocaloric diet suggested with dairy food products.

Results:
Anthropometric measurements showed a highly significant change among cases (P < 0.001). Among cases, systolic blood pressure showed a significant difference (P < 0.01) after 6 months. Biochemical parameters among cases showed significant changes among fasting plasma glucose (P < 0.01), fasting insulin (P < 0.05) and homeostatic model assessment-insulin resistance (HOMA-IR) (P < 0.01). Significant changes were also observed among cases in biochemical parameters, i.e., total cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein, very-low-density lipoprotein (VLDL), total lipids, non-HDL cholesterol, cholesterol HDL ratio and Quantitative Insulin Sensitivity Check Index(OUICKI) (P < 0.001). High-sensitive C-reactive protein, tumour necrosis factor alpha and adiponectin also showed significant change after 6 months (P < 0.001). Nutrient intake also showed statistically significant change after intervention (P < 0.001) except in the intake of phosphorus and calcium (P > 0.05). A positive correlation was noticed between systolic blood pressure with weight, body mass index, waist circumference, and percent body fat and between adiponectin and waist–hip ratio. HOMA-IR and QUICKI also showed a positive correlation with energy intake (P < 0.05).

Conclusion:
Incorporating a hypocaloric diet with dairy food products helps in harmonising the biomarkers of weight gain among respondents.
Prevalence of Diabetes Mellitus and Hypertension in Endodontic Patients
Authors: Ahirwar Anupama , Bhargava Anuj , Gupta Neha Nigam 
Published: June 2021

Aim:
The aim of this study was to estimate the prevalence of diabetes mellitus (DM) and hypertension (HTN) in patients-seeking endodontic treatment at a tertiary care center.

Materials and Methods:
This retrospective, institutional-based, cross-sectional study was conducted from 2018 to 2020 on 300 study participants between 30 and 70 years of age, using the data obtained from the records of patients who had no known history of HTN and DM and who were clinically advised to undergo endodontic treatment. Fasting blood sugar level and blood pressure were recorded for each study participant. Clinical data parameters were analysed, and the Chi-square statistical test was applied.

Results:
Out of 300 patients, 19.3% (58 patients) were diagnosed with DM and 17.7% (53 patients) were diagnosed with HTN. Statistically, a high significant difference was found in the prevalence of DM and HTN among endodontic patients according to age with the highest prevalence demonstrated in the age group of 61–70 years. No significant difference was found in the prevalence of both diseases according to gender.

Conclusion:
Within the limitations of our study, it may be concluded that the estimated prevalence of DM and HTN in this study points as a risk indicator, especially in older age group population undergoing endodontic treatment. It is thus, advised that a clinical protocol of prior referral to a family physician for detailed pre-operative clinicopathological screening and systemic evaluation before performing any endodontic treatment be devised for all age groups to avoid medical complications and/or modifications if any, that may be required in endodontic treatment of undiagnosed DM and HTN patients.