bluuebunny/crossref_metadata_2025_split huggingface dataset:
Romantic Microethics
Authors: Freer Alexander 
Published: November 2021

AbstractEthical thought typically aims to provide a general account of the good. This essay explores a form of localized ethical attention through British Romantic writing that eschews that aspiration, privileging individual cases in all their detail and particularity. This form, which I term “microethics,” is small in two senses, permitting extremely close observation of individual cases and limiting itself to equally small conclusions. It is most recognizable in poetry but recurs across fiction, drama, and philosophical prose. Considering such thinking allows us to assess and extend recent arguments for the value of Romanticism's small and marginal forms. While Romantic microethics develops in opposition to emerging utilitarian thought and the politically repressive conditions of the 1790s, it anticipates a range of later forms, from Adorno's ethical fragments to deconstruction to anthropological method. At once literary and philosophical, it binds both writing and reading practices to acts of singular attention.
Saúde mental e qualidade de vida de pais de pessoas com TEA durante a pandemia COVID-19: uma revisão narrativa
Authors: Medrado Aracelles Alvarenga , Campos Rafael Cabral , Siquara Gustavo Marcelino , Pondé Milena Pereira 
Published: November 2021

INTRODUÇÃO: Em dezembro de 2019 surgiram, na China, os primeiros caso de COVID-19, uma doença infectocontagiosa que, em poucos meses, evoluiu para o estado de pandemia. Foram adotadas medidas de distanciamento social, que podem gerar impactos psicológicos negativos para a população. O impacto pode ser maior para os pais de indivíduos com TEA, já que as demandas de cuidados dos filhos passam para os genitores em tempo integral. Soma-se ainda o fato de o trabalho dos pais em home-office e as demandas de trabalho doméstico. OBJETIVO: Revisar estudos sobre a saúde mental e/ou qualidade de vida de pais durante a pandemia. METODOLOGIA: Trata-se de uma revisão narrativa da literatura buscando-se artigos nas bases PubMed/Medline, Scielo (Scientific Electronic Library Online), Google Scholar, Portal BVS (Biblioteca Virtual em Saúde), Periódicos Capes (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior). Foram selecionados 12 artigos de estudos qualitativos transversais a partir das bases de dados. RESULTADOS: A avaliação dos artigos mostra que os pais de indivíduos com TEA tendem a estar mais ansiosos, estressados e depressivos nesse período devido a sobrecargas físicas e emocionais. Além disso, eles apresentaram pior qualidade de vida neste período quando comparado a pais de crianças com outros transtornos e com desenvolvimento típico. CONCLUSÃO: O desenvolvimento de mais estudos sobre o tema é necessário, pois com maior embasamento científico é possível planejar um cuidado mais direcionado. O apoio virtual de profissionais e outros pais podem minimizar o impacto da pandemia sobre essa população. Entretanto, a diversidade de fatores sociais, econômicos e culturais envolvidos nessa questão requer mobilização multisetorial.
Palavras-chave: Transtorno do espectro autista. Pais. Saúde Mental. Qualidade de Vida. COVID19.
Transtorno de personalidade borderline em homens: uma revisão integrativa
Authors: Nascimento Rodrigo Barbosa , Cerqueira Gabriela de Lima , Araujo Filho Emanuel Santos de , Carneiro Daniela Gomes 
Published: November 2021

OBJETIVO: Apresentar e sistematizar as principais evidências científicas a respeito do transtorno de personalidade borderline em homens (TPB). MÉTODO: Durante o período de abril de 2021, realizou-se uma revisão integrativa da literatura científica acerca da temática em questão, sendo utilizados os descritores indexados no DeCS: Transtorno da Personalidade Borderline; Transtorno da Personalidade Limítrofe; Masculino; Fatores Desencadeantes; Cognição; Neurobiologia; Comportamento Social. Para realizar a pesquisa, os descritores foram combinados nas bases de dados Medline, Lilacs e EBCS nos sites de Busca Pubmed e na Biblioteca Virtual em Saúde – BVS. RESULTADOS: Foi possível identificar algumas alterações comportamentais, de humor e neuropsicológicas em homens com TPB. Dentre as alterações comportamentais, a mais prevalente foi a agressão (37,5% dos artigos). Do mesmo modo, a alteração de humor mais encontrada foi a desregulação emocional (12,5% dos artigos), muito comum em pacientes com TPB; igualmente, as alterações a nível neuropsicológico com maior quantidade de achados envolvem alterações na região da amígdala (20,83% dos artigos), córtex (16,66% dos artigos), bem como o hipocampo (16,66% dos artigos), regiões essenciais para o controle do humor e tomada de decisão. CONCLUSÃO: Foi possível concluir que existem algumas alterações comportamentais, de humor e neuropsicológicas que são mais prevalentes no gênero masculino, sobretudo aquelas que envolvem agressão, raiva e seus fatores neuropsicológicos associados. Dito isso, considera-se que a sistematização dessas informações contribui na identificação e controle dos casos de TPB em homens, assim como colabora para o desenvolvimento científico do campo da psicopatologia em relação aos processos que envolvem tal patologia
A comparative study of the technical feasibility of complete salpingectomy versus tubal ligation as a method of tubal sterilisation during caesarean delivery
Authors: Gupta Taru , Baruhee Divya , Agarwal Sunaina 
Published: November 2021

Background: Recent theory on ovarian malignancy suggests its origin from primary foci in fallopian tubes. Prophylactic salpingectomy may benefit in risk reduction of ovarian cancer. The aim of the study was to compare the feasibility of complete salpingectomy with bilateral tubal ligation was made during caesarean delivery in women desirous of permanent sterilisation.Methods: We conducted a prospective interventional randomized control study in department of obstetrics and gynaecology, ESI-PGIMSR Basaidarapur, New Delhi from October 2018 to February 2021. 70 women participated in this study desiring permanent sterilisation during caesarean delivery. Patients were randomized into two groups who either underwent bilateral tubal ligation [group A (N=35)] or complete bilateral salpingectomy [group B (N=35)].Results: Procedure was completed in 91% patients in group A and 77% in group B (p >0.05) making both the procedures feasible. Total operative time (min) in group A and B were 47 and 55 respectively (p<0.01). Mean sterilisation procedure time (min) in group A was 5 and group B was 6 (p=0.13). No significant difference was seen in intra-operative blood loss (400 ml in group A vs 300 ml in group B), percentage decrease in post-op haemoglobin (g/dl) (4.56±2.96 in group A vs 3.91±2.7 in group B), post-operative serum Anti-mullerian hormone (AMH) levels (ng/ml) (group A-0.965±0.12 vs 0.7±0.09 in group B) in the two groups.Conclusions: Salpingectomy as an alternative to tubal ligation should be discussed with suitable patients desirous of permanent sterilisation during caesarean delivery.
Case report of malignant peripheral nerve sheath tumor of parotid in a patient with neurofibromatosis type 1
Authors: P. Anuradha , Reddy Bathi , Gaur Suhail 
Published: November 2021

<p>Malignant peripheral nerve sheath tumor (MPNST) refers to spindle cell sarcomas arising from or separating in the direction of cells of the peripheral nerve sheath. The MPNST of the parotid gland is an extremely rare tumor, accounts for &lt;5% of all soft tissue sarcomas, and carries a poor prognosis. Diagnosis of MPNSTs is usually based on histopathology aided by IHC, which reflects the Schwann cell differentiation in this neoplasm. Approximately 50-90% of MPNSTs are positive for S-100 protein. A 56-year-old male presented with right parotid swelling for 3 months and incomplete right eye closure. The patient was diagnosed with neurofibromatosis 1 (NF-1) and pulmonary tuberculosis in the past. On Examination, a hard, tender swelling measuring 5×4 cm involving the right parotid gland and right grade 2 LMN facial palsy was noted. Histopathology was suggestive of a MPNST.</p><p><strong> </strong></p>
Maternal and perinatal outcomes of pregnancies complicated by cardiac disease at a tertiary level hospital
Authors: Chaudhary Niharika , Pulakhandam Naga Veni Prapurna , Annapoorna Y 
Published: November 2021

Heart disease in pregnancy is one of the leading non-obstetric causes of maternal mortality and is the leading cause of maternal intensive care unit admissions in the world. To study the prevalence of heart disease in antenatal mothers and fetal outcome with obstetric management. The presence of comorbidities and the occurrence of obstetric, fetal, and cardiovascular complications during delivery among women with heart disease hospitalized for delivery were studied in 35 women at GSL Medical College, Rajahmundry for a period of 1 year from 01/01/2019 to 1/1/2020: Over a period of 12 months, 35 subjects were recruited. During this period, there were 5005 deliveries. The majority of women were aged between 20-25yrs and were unbooked cases belonging to NYHA class I or II. Cesarean section and operative vaginal delivery were more common. Despite the multidisciplinary approach, 3 women succumbed to the disease of which one was a case of severe rheumatic heart disease with valve failure, the second was a case of postpartum cardiomyopathy and the third was a case of severe pulmonary arterial hypertension. Fetal outcome in cardiac patients is usually good and only a little different from those patients who do not suffer from heart disease. Pregnant women with heart disease were more likely to experience adverse events during delivery. These women require a multidisciplinary team for optimal maternal and foetal outcomes.
The effect of COVID-19 on maternal and neonatal outcome - A retrospective study
Authors: Garg H , Rai Swati , Ahuja M , Goel N , Srivastava R , Agrawal S 
Published: November 2021

The pandemic of coronavirus disease (COVID-19) has caused serious adverse effects on the human race. There are limited data on maternal and neonatal outcomes of pregnant women with COVID-19.An observational descriptive study was conducted in the department of obstetrics & gynaecology at SMSR and Sharda hospital located in Greater Noida, Uttar Pradesh. This medical college drains patients from entire Greater Noida and as well as from far-away places as referrals. All pregnant patients were included that came to this hospital from 1 April to 31 May 2021. These were the two dreadful months for the entire country in which so many lives were lost. All pregnant patients were labelled COVID-19 positive after undergoing either Rapid antigen test/RTPCR test taken from nasopharyngeal and oral swab.: This included assessment of the maternal morbidity and mortality, comorbidities & worsening of outcome due to COVID-19 infection in pregnant patients as well assessment of the effect of COVID-19 infection on fetus and newborn.
A retrospective analysis of clinical profile of patients with cancer cervix in a rural medical college in Karnataka
Authors: Bhavya H U  , Ellian Muna , Doppa Geeta J 
Published: November 2021

Cancer cervix is most common cause of cancerous deaths in females especially in developing countries. The pre-invasive stage of cervical cancer lasts for a long period and a small proportion progresses to an invasive lesion. In Indian set up, majority of the patients are presenting with an invasive lesion. To describe the clinical profile of patients presented with cervical cancer and to describe various treatments received by those patients.: The present study is a retrospective observational study done on confirmed cases of carcinoma cervix who attended rural medical college in Karnataka. Clinical records of the patients, who presented between November 2019 and November 2020 and were diagnosed with cervical cancer, were retrieved. The data related to demographic and clinical variables like age, socioeconomic status, education, symptoms, clinical staging, treatment and histopathology report were recorded. Data collected were entered in Microsoft Excel Office 2007and data analysed. Data were presented using descriptive statistics. The data was expressed in the form of frequencies and percentagesA total of 30 patients with the median age of 46 years were studied. Most common presentation was post coital bleeding (40%) followed by white discharge per vagina in 33%. Majority were under low socioeconomic status (70%). 60% presented in stage II and 30% in stage I. Chemoradiation was treatment of choice in 60% followed by surgery in 33% and 7% were lost to follow up. On histopathology, majority had squamous cell carcinoma (70%).The appropriate management of Cervical intraepithelial neoplasia(CIN) can prevent invasive cervical cancer. In this study most of them presented in advanced stage which could have been prevented with the regular screening and awareness among women in the reproductive age group. : Detection of pre invasive lesions or in situ cases remains important key to decreasing cervical cancer morbidity and mortality.
Effect of traditional versus site specific anterior repair in reduction of urinary symptoms in women with pelvic organ prolapse
Authors: Sawant Aditi , Bhalerao Anuja , Bhalerao Kritika 
Published: November 2021

The present study was undertaken to evaluate effect of traditional anterior repair versus site specific anterior repair in reduction of urinary symptoms in women with Pelvic organ Prolapse. During the study period of 2 years 140 women belonging to reproductive, peri-menopausal and postmenopausal age groups were included in the study. Employing past literature, the sample size calculated was 140. All women were assessed pre-operatively by the assessment method – Pelvic organ prolapse quantification (POP-Q) system. 70 women belonging to Group A were treated according to vaginal hysterectomy with traditional anterior repair and 70 women belonged to Group B who were treated according to vaginal hysterectomy with site specific anterior repair.Post-operatively, all women were followed up till 7th post-operative day and were assessed for anatomical and functional improvement to determine a better method for repair in reduction of urinary symptoms in women with pelvic organ prolapse.Our study shows functional and anatomical outcomes of traditional anterior repair and site specific anterior repair. 48 of 70 women (68.2%) who were subjected to traditional anterior repair and 52 of 70 women (73.4%) who were subjected to site specific anterior repair had marked functional improvement after surgery. 58 of 70 women (83.2%) belonging to traditional anterior repair group and 67 of 70women (95.3%) belonging to Site specific anterior repair group had considerable anatomical improvement post-operatively. This impresses the role of site specific anterior repair in women with pelvic organ prolapse for attaining better functional and anatomical outcome.
Comparing effectiveness of COBAS HPV test with VIA/VILI, pap smear and colposcopy for screening of cancer cervix
Authors: Subramanian Lalitha , Indirani T V , Suji I Igena Sharo 
Published: November 2021

Cancer cervix is the second leading cancer causing 21% of all cancer deaths. Cervical cancer can be prevented if detected by premalignant changes and is curable in its earliest stage. Various procedures including VIA/VILI, pap smear have been routinely used for the purpose of screening cervical cancers. Infection with Human Papilloma virus is the principal cause of cancer cervix. Roche COBAS HPV test was approved by US FDA on April 24, 2014 as one of the first line primary screening method for cancer cervix based on the presence of high risk HPV DNA. The FOGSI guidelines in January 2018 has suggested cobas HPV test for cancer cervix screening. This study was conducted on 100 women with high risk cervical lesions during the period of 18 months. Women attending the NCD clinic of Government Thoothukudi Medical college hospital were taken for the study. The women were to undergo VIA/VILI, Pap smear study and subjected to COBAS HR HPV Test after their consent. Cervical specimens collected in PreservCyt solution using an endocervical brush/ spatula or collected in SurePath preservative fluid using a cervical broom were sent for COBAS HR HPV test. Collected sample kits were recruited in Department of Radiation oncology, Government Thoothukudi medical college for storage at low temperature for a short period, after pooling of samples, these were sent through the Department of radiation oncology to Adayar cancer institute, Chennai, with which the department has treated with for COBAS HPV test. The results were analysed and proceeded.This study has proven that screening for high risk HPV test in cervical specimen can easily pickup the premalignant lesion with high sensitivity, specificity when compared with other screening tests. Hence, this study emphasizes the importance of implementing HPV tests that can provide a 3-year screening free interval, compared to yearly pap screening. The other advantage is that the results are available immediately reducing the frequency of visits to hospital for further follow up on colposcopy/biopsy.
Study of bad obstetric history cases attending tertiary care centre, Tirupati
Authors: Gowthami B  , Kumari J Sowjanya , Narayanamma V Lakshmi 
Published: November 2021

To assess the obstetric and medical risk factors in patients with bad obstetric history (BOH) and outcome of pregnancy in case of BOH. A prospective cross-sectional study was conducted in Government maternity hospital, Tirupati for a period of 1 year from December 2017 to November 2018. All pregnant women who were fulfilling inclusion criteria of BOH, as study group and all possible variable were compared with control group, who got selected randomly from the rest of deliveries. And analysed the results in terms of sociodemographic factors, risk factors, pregnancy complications, mode of delivery, maternal and foetal outcome. Of 102 pregnant women in BOH, 76.5% were in age group between 21-30yrs, and 14.7% in age group &#62;30yrs. Primary Recurrent pregnancy loss (RPL) was 51% and that of secondary recurrent pregnancy loss was 49%.History of hypertensive disorders including preeclampsia, eclampsia and chronic hypertension, noted in 11.8% cases, which was higher than previous studies, indicating changing trends in incidence.In foetal complications IUGR (0% vs 9.8%, p=0.026) and IUFD (0% Vs 7.8%, p=0.05) were more in BOH group and statistically significant also. Even though the maternal complications were more in BOH group, there was no statistical significance (P=0.075).Among the various causes of RPL found in the present study, endocrine causes were seen in 12.7%, Anatomical causes were found in 11.8% and in about 63.7% cases no definite cause was found and aetiology was unexplained. Present study, supporting the change in definition of recurrent pregnancy loss from 3 consecutive losses to 2. So early evaluation and with appropriate interventions in most of couples outcomes were fruitful.
Resurgence of classical caesarean section in current obstetric practice- A case series
Authors: Mathe Priyanka , Wadhwa Sanjana Narula , Gupta Taru 
Published: November 2021

Although, the incidence of placenta accreta spectrum (PAS) and large fibroids is rare but still these cases contributes to a large number of maternal morbidity and mortality. Major obstetric hemorrhage is one the dreadful complication of these types of cases and thus early diagnosis and intervention in such cases helps the physician to minimize the risk to mother and the fetus. Also, current widespread use of ultrasound has helped us to manage these cases judiciously, predict and prevent life threatening obstetric hemorrhage. Here we present three complicated obstetric cases of placenta accreta, large lower segment uterine fibroid and large cervical fibroid which necessitated classical cesarean sections (CCS) thus emphasizing prowess in CCS in modern obstetric era. High index of suspicion, Multidisciplinary approach alongwith expert surgical personnel should be available in high risks cases like placenta accreta syndrome and large fibroids in pregnancy.
A histopathological study of unusual findings in appendectomy specimens in a tertiary care hospital of Andhra Pradesh
Authors: Kona Suneetha , Kande Srinivasulu , Prasanna Boddu Penchala , Kancharla Sushma Chandulee 
Published: November 2021

Acute appendicitis is sudden inflammation of the appendix, usually initiated by obstruction of the lumen. This results in invasion of the appendix wall by gut flora, and it becomes inflamed and infected.: To investigate retrospectivelythe prevalence and implications of unusual histopathological findings in appendectomy specimens from patients with suspected acute appendicitis.This is retrospective assessment of hospital records of 150 patients who were diagnosed as acute appendicitis and underwent appendicectomy during March 2018 to February 2020 at Government Medical College, Bhagya Nagar, Ongole, Andhra Pradesh .Data of the patients were assessed based on age, sex, histopathological diagnosis, coexisting pathologies and uncommon findings on histology. According to histopathology report, negative for acute appendicitis were noted in 82 cases (55%), whereas positive for acute appendicitis in 68 cases (45.3%) . Rare findings were foundin 38 (55.8%) cases out of 68 cases. Parasites were found in 7 (18.4%) (Enterobius Vermicularis, Balantidum Coli, Schistosoma Haematobium), Mucocele in 12 (32%), carcinoid tumour in 8(21%), B cell malignant lymphoma in 2 (5%), leiomyoma in 2 (5%), Primary appendiceal adenocarcinoma in 3 (8%), Acute appendicitis with dysplastic changes in 2 (5%) and inflammatory bowel polyp was reported in remaining two cases(5%).: Even though unusualpathologies can be seen rarely during appendectomy, this should be kept in mind for further evaluation of each cases.
COVID-19 and interdisciplinary research: What are the needs of researchers on aging?
Authors: White P.J. , Alders Gésine , Patocs Audrey , Raina Parminder 
Published: November 2021

COVID-19 has had an extreme effect on older people. Now more than ever we need collaborative approaches to address complex issues within research on aging. However, the pandemic has dramatically changed the way we conduct, interact, and organize research within interdisciplinary groups. This paper describes a case study of how an interdisciplinary institute for research on aging has managed the process of change during COVID-19 restrictions. A design lead, researcher centered approach was used to understand the needs of researchers as they adapted across 6 months. Firstly, an online survey (n=51) was conducted to understand the scope of change and needs. The survey found broad themes ranging from assistance with finding additional funding to adjusting current research proposals. Following the survey, two Co-Design Sessions were conducted. The first session (n=53) diverged thinking to scope ideas from the survey and actionable themes were created. The second session (n=36) was conducted to converge thinking and focus on solutions based on one of these themes. The results revealed a diversity of ideas addressing the needs of interdisciplinary researchers in aging. These ideas spanned from exploring the capacity to do research remotely and creating virtual collaboration spaces to rethinking stakeholder engagement.
Received: 1 July 2021Accepted: 12 October 2021