bluuebunny/crossref_metadata_2025_split huggingface dataset:
Location and Strength of Malvolio Expression in Chinese Honeybee Reveals Its Potential Role in Labor Division
Authors: Ma Weihua , Meng Jiao , Zhen Xianyun , Zhao Huiting , Li Wanghong , Gao Ye , Jiang YuSuo 
Published: April 2021

Abstract
The malvolio (mvl) gene plays an important role in the transition from nursing to foraging in honeybees (Apis mellifera). Apis cerana cerana (A. c. cerana) is a subspecies of the eastern honeybee, well-known for its pollinator role throughout China. Although A. c. cerana shares many characteristics with A. mellifera, it is unclear whether Acmvl plays a similar role to Ammvl in foraging behavior. In this study, Acmvl expression was quantified during the transition from nursing to foraging in A. c. cerana. Acmvl protein production was also characterized in different tissues in bees from three behavioral groups. Finally, in situ hybridization was used to describe Acmvl expression patterns in forager bee brains. Acmvl expression was low early in life but then showed a major peak, which suggests its role in labor division. Examination of tissue type revealed that Acmvl expression was highest in the thoraxes of nurse bees and the heads of forager bees. In bee brains, Acmvl was selectively expressed in the somata of Kenyon cells in the mushroom bodies, optic lobes and antennal lobes. Taken together, these findings suggest that Acmvl plays a role in the nurse–forager transition of A. c. cerana.
Assessment of the morphometry of heads of normal sperm and sperm with the Dag defect in the semen of Duroc boars
Authors: Banaszewska Dorota , Andraszek Katarzyna 
Published: April 2021

Abstract

Introduction
The Dag defect is one of the primary morphological defects in sperm correlating with reduced fertility. This defect is found in the spermatozoa of many livestock species. The aim of the study was to assess the morphometry of the heads of normal sperm and sperm with the Dag defect in the semen of Duroc breeding boars.

Material and Methods
Sperm morphology was examined in ten ejaculates each from 12 Duroc boars. In total, 3,600 morphologically normal sperm and 838 sperm with the Dag defect were evaluated. The area, perimeter, length and width of the sperm head were measured and these basic morphometric parameters were used to calculate four additional shape indices characterising the sperm head, i.e. ellipticity, elongation, roughness and regularity.

Results
Sperm with this defect had markedly smaller heads, 0.32 μm shorter and 0.19 μm narrower than the heads of sperm with normal morphological structure. The heads of sperm with the Dag defect also had a 1.1μm smaller perimeter and a 2.5 μm2 smaller surface area than the heads of morphologically normal sperm.

Conclusions
The Dag defect is found in boar sperm irrespective of the age of the individual. It affects the morphology of the sperm head.
Investigation of the prevalence of Mycoplasma ovipneumoniae in Southern Xinjiang, China
Authors: Zhao Jin-yu , Du Yi-zhou , Song Ya-ping , Zhou Peng , Chu Yue-feng , Wu Jun-yuan 
Published: April 2021

Abstract

Introduction
It is very important to monitor the infection of Mycoplasma ovipneumoniae as a potential threat to the sheep industry. Southern Xinjiang is a major sheep breeding base in China, however, there is no relevant information concerning the infection of the region’s ovine stock with this bacteria at present. This study aimed to address this knowledge gap.

Material and Methods
A total of 824 nasal swabs and the lungs of six sheep that died of pneumonia were collected in four regions between 2018 and 2020. Primers specific for M. ovipneumoniae and universal ones for the genus were used for PCR. Sequencing was undertaken of 159 universal primer-positive samples (153 nasal swabs and 6 lungs) and of 84 specific primer-positive samples (80 nasal swabs, 20 per region; and 4 lungs, 1 per region). The lungs were also sampled for the isolation of M. ovipneumoniae. A phylogenetic tree based on partial sequences of the Mycoplasma 16S rRNA gene was built.

Results
The overall nasal swab positive rate for M. ovipneumoniae was 40.78%; the rate of animals older than 12 months was significantly different to those of younger sheep (< 3 months, 53.39%; 3 – 12 months, 46.01%; >12 months, 31.76%). Four strains of M. ovipneumoniae were isolated from six lungs. Phylogenetic analysis indicated their origin outside southern Xinjiang. Two other species were also detected: M. arginine and M. conjunctivae.

Conclusion
Our survey indicated that a high level of M. ovipneumoniae asymptomatic colonisation in sheep, especially in lambs, affects southern Xinjiang and also confirmed the existence of M. conjunctivae and M. arginine. Our results showed that the health of sheep in southern Xinjiang is facing a great threat, and relevant prevention and control measures should be strengthened.
Class struggle in the era of post-politics
Authors: Abalo Ernesto , Jacobsson Diana 
Published: April 2021

Abstract
This article addresses how class as a category of conflict and struggle is understood and shaped discursively in mainstream media today. We utilise a case study of how Swedish news media represents the long-lasting conflict in the Swedish labour market between the Swedish Dockworkers’ Union and the employer organisation, Sweden's Ports. Using critical discourse analysis, we show two ways in which class relations are recontextualised in three Swedish newspapers. One is through obscuring class and centring the conflict around business and nationalist discourses, which in the end legitimise a corporate perspective. The other, more marginalised, way is through the critique of class relations that appears in subjective discourse types. This handling of class, we argue, serves the reproduction of a post-political condition.
Anti-tumor agents: Design, Synthesis, and Biological study of N-Substituted-7-hydroxy-1-azacoumarin-3-carboxamide derivatives as potent cytotoxic agents
Authors: Bakare Safyah B. 
Published: April 2021

Abstract
Synthesis of ethyl 7-hydroxy-1-azacoumarin-3-carboxylate (3) was developed using ethyl-7-hydroxy coumarin-3-carboxylate and ammonium solution as the key synthons. Condensation of ethyl 7-hydroxy-1-azacoumarin-3-carboxylate with ammonium acetate and aniline to give N-substituted-7-hydroxy-1-azacoumarin-3-carboxamides (7-Hydroxy -1-azacoumarin-3-carboxamide (4) and N-phenyl 7-Hydroxy-1-azacoumarin-3-carboxamide (5)). Bromo derivative (N-phenyl 6, 8-dibromo-7-hydroxy-1-azacoumarin-3-carboxamide (6)) was obtained from halogenation of compound N-phenyl 7-Hydroxy-1-azacoumarin-3-carboxamide (5) with bromine in glacial acetic acid. N-phenyl-2,5-diacetoxy-6, 8-disubstituted-Quinoline-3-carboxamides (N-phenyl 2,7-diacetoxy-Quinoline-3-carboxamide (7) and N-phenyl 2,7-diacetoxy-6,8-dibromo-Quinoline-3-carboxamide (8)) were prepared via the acetylation of compounds 5 and 6 with acetic anhydride. Five compounds 4–8 were evaluated in vitro against more than one human tumor cell lines. Among the selected compounds, 6 showed the best in vitro cytotoxicity against the human cancer cell line; MCF-7 (with IC50 = 10.12 μM). In addition, cell cycle analysis of compound 6 demonstrated cell cycle arrest at G2/M phase and Pre-G1 apoptosis.
The Importance of the World Kidney Day World Kidney Day – 11 March 2021 – Living Well with Kidney Disease
Authors: Polenakovic Momir H. , Dohcev Saso , Rambabova-Bushljetik Irena , Gjorgjievski Dusko , Spasovski Goce 
Published: April 2021

Abstract
World Kidney Day (WKD) is a global campaign to raise awareness of the importance of our kidneys to overall health and to reduce the frequency and impact of kidney disease and associated health problems worldwide. Kidney disease is a non-communicable disease (NCD) and currently affects around 850 million people worldwide. One in ten adults has chronic kidney disease (CKD). The global burden of CKD is increasing, and is projected to become the 5th most common cause of years of life lost globally by 2040. CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume 2–3% of the annual healthcare budget in high-income countries. Crucially, kidney disease can be prevented and progression to end-stage kidney disease can be delayed with appropriate access to basic diagnostics and early treatment. This year World Kidney Day continues to raise awareness of the increasing burden of kidney diseases worldwide and to strive for kidney health for everyone, everywhere. During the pandemic with COVID 19 patients kidneys are also damaged, apart from the respiratory tract and other organs. It can lead to an increase in acute renal failure and consequent chronic kidney insufficiency, as well as number of deaths. Therefore, it is important to evaluate the renal function in each patient with COVID 19 virus. In the Republic of North Macedonia from 2006 to present day nephrologists and other medical personnel devoted to the early diagnosis, prevention and treatment of renal disease have participated in the activities of the World Kidney Day. These activities were supported by the Macedonian Society of Nephrology, Dialysis, Transplantation and Artificial Organs, the Department of Nephrology at the Medical Faculty, the Macedonian Academy of Sciences and Arts, the Government of the Republic of North Macedonia, non-governmental nephrology organizations (NEFRON) and the media. There were lectures and presentation devoted to the various theme of the WKD, publications in journals, as well as activities for examination of the renal function of patients in the medical centers. The activities during the WKD contributed to the improvement of the nephrological protection of the citizens of the Republic of N. Macedonia.
2-Methoxyestradiol Attenuates the Development and Retards the Progression of Hypoxia-And Alpha-Naphthylthiourea-Induced Pulmonary Hypertension
Authors: Tofovic Stevan P. , Zhang Xinchen , Jones Tom J. , Petruševska Gordana 
Published: April 2021

Abstract
Pulmonary arterial hypertension (PH), a progressive, incurable, and deadly disease, predominantly develops in women. Growing body of evidence suggest that dysregulated estradiol (E2) metabolism influences the development of PH and that some of the biological effects of E2 are mediated by its major non-estrogenic metabolite, 2-metyhoxyestradiol (2ME). The objective of this study was to examine effects of 2ME in chronic hypoxia (CH)-induced PH and alpha-naphthylthiourea (ANTU)-induced acute lung injury and PH. In addition, we investigated the effects of exposure to different levels of CH on development of PH. Chronic exposure to 15% or 10% oxygen produced similar increases in right ventricle peak systolic pressure (RVPSP) and pulmonary vascular remodeling, but oxygen concentration-dependent increase in hematocrit. Notably, right ventricle (RV) hypertrophy correlated with level of hypoxia and hematocrit, rather than with magnitude of RVPSP. The latter suggests that, in addition to increased afterload, hypoxia (via increased hematocrit) significantly contributes to RV hypertrophy in CH model of PH. In CH-PH rats, preventive and curative 2ME treatments reduced both elevated RVPSP and pulmonary vascular remodeling. Curative treatment with 2ME was more effective in reducing hematocrit and right ventricular hypertrophy, as compared to preventive treatment. Single ANTU injection produced lung injury, i.e., increased lungs weight and induced pleural effusion. Treatment with 2ME significantly reduced pleural effusion and, more importantly, eliminated acute mortality induced by ANTU (33% vs 0%, ANTU vs. ANTU+2ME group). Chronic treatment with ANTU induced PH and RV hypertrophy and increased lungs weight. 2-ME significantly attenuated severity of disease (i.e., reduced RVPSP, RV hypertrophy and pulmonary vascular injury). This study demonstrates that 2ME has beneficial effects in chronic hypoxia- and acute lung injury-induced PH and provides preclinical justification for clinical evaluation of 2ME in pulmonary hypertension.
Posterior Urethral Valve and Prenataly Resolved Multicystic Dysplastic Kidney
Authors: Aluloska Natasha , Palchevska Snezana , Simeonov Risto , Gucev Zoran , Tasic Velibor 
Published: April 2021

Abstract
Multicystic dysplastic kidney is a rare congenital anomaly of the kidney and urinary tract. The association with the posterior urethral valve is also very rare. Here we present a patient with both entities and prenatal resolution of the cysts.
A 10-week old baby was referred for nephrourological work up due to prenatal diagnosis of the left multicystic kidney. He had serial US scans during the pregnancy. Immediately before delivery the cysts were not seen (prenatal resolution). There were no extrarenal anomalies. The first postnatal ultrasound scan revealed normal sized right kidney without dilatation of the pelvicalyceal system. The bladder had normal thickness of the wall. Technetium-99m dimercaptosuccinic acid scan showed no activity on the left side, and the right kidney appeared normal. At two months of age, a poor urinary steam was observed and additional urologic work up was indicated on clinical suspicion of PUV. Voiding urethrocystography revealed posterior urethral valve and the baby underwent cytoscopic valve resection.
Conclusion: We present a rare association of two congenital anomalies of the kidney and urinary tract with prenatal involution of the multicystic dysplastic kidney that is extremely rare event as seen in our case. Presence of posterior urethral valve must be suspected in a male baby with a poor urinary stream even when his ultrasound scan of urinary system appears normal.
Testing of Priorities in the Research of Cultural Heritage in Slovakia’s Depopulated Regions
Authors: Murin Ivan 
Published: April 2021

AbstractAlong with the dynamics of findings of several scientific disciplines of the recent decades, the mechanisms and processes of culture transmission seem to be much more apparent. The knowledge about cultural heritage and the inheritance of culture produced in this way have led to the creation of several platforms of critical cultural heritage. Anthropological and ethnological findings significantly enrich these multi-disciplinary environments where the criterion of a living cultural heritage is becoming generally accepted. In this light, the Arts and Humanities Research Council (AHRC) created a working group in 2019 with the aim to prepare an innovated Strategic Research Agenda (SRIA) for the submission of European projects in the field of cultural heritage (JPI CH). The working group invited Slovak and Czech researchers to reflect on the knowledge from the Central European research area in order to define the research topics for the priority Cultural Heritage and People. The research on the testing of the priority and clarification of the impacts of the depopulation of cultural regions on cultural heritage was conducted at selected locations of the Hont, Novohrad and Malohont regions. The key indicators for justifying the inclusion of the research topicThe impact of the depopulation of EU regions with cultural heritagein SRIA include ethnographic information, historical demographic data and the modelling of the transmission of cultural heritage content to the next generations.
Long-Term Dynamics of Trophic State Indicators in Phytoplankton of the Cooling Reservoir of a Nuclear Power Plant
Authors: Novoselova Tatiana , Barinova Sophia , Protasov Alexander 
Published: April 2021

Abstract
The dynamics of long-term indicators of trophicity in the cooling pond of a nuclear power plant in Ukraine was analyzed by phytoplankton biomass and bioindicators of trophicity. Greater species richness correlated with the number of species-indicators of greater trophicity. During the contourization processes caused by the introduction of filter-feeding mollusks and changes in the operating mode of the nuclear power plant, there was a decrease in the abundance of phytoplankton and trophic state. During decontourization, there was a sequential “return” of previously eliminated taxa and the restoration of the number of indicator species.
Host Selectivity ofNerocila Orbignyi(Guerin-Meneville, 1832) (Isopoda, Cymothoidae) with a Record of a New Host from the Sea of Marmara (Turkey)
Authors: Öktener Ahmet , Trilles Jean Paul 
Published: April 2021

AbstractNerocila orbignyi(Isopoda, Cymothoidae) is reported for the first time onMugil cephalusLinnaeus, 1758 (Pisces, Mugilidae) from Bandırma Bay (the Sea of Marmara, Turkey) during 2020. This paper aims to present the morphological characters of male ofN. orbignyifrom Turkey. Hosts infested withN. orbignyiare commented according to taxonomical status (order, families), ecological behaviours (habitat selections, feeding habits, school-solitary), morphological characters (scale types) according to current records. It may be said thatN. orbignyihas been reported more frequently on fish belonging to the Perciformes order and Mugilidae and Sparidae families. It may also be said that this parasite selects also the fishes with carnivorous, demersal, schools, and migratory character.
Predation By the Nonnative Rainbow Trout, Oncorhynchus Mykiss (Walbaum, 1792), on the Native Biota from Freshwater Environment of the Central Andes (Argentina)
Authors: Rios Juan Manuel 
Published: April 2021

Abstract
This study aimed to examine the impact of the nonnative rainbow trout Oncorhynchus mykiss on the native biota that inhabits freshwater environments of the central Andes, Argentina. To assess the predation pressure on native Andean vertebrates and invertebrates, the stomach contents were taken from rainbow trout caught at three Andean sites. Results showed that the major prey items were the native torrent catfish Hatcheria macraei (100% in diet), Elmidae coleopterans (23%), and the native crab Aegla affinis (38%) in the rainbow trout stomachs collected from Cipolletti Dam (North zone), Yaucha River (Middle zone), and Vaina Stream (South zone), respectively. This preliminary study exhibits the predation pressure of the rainbow trout on native Andean species and suggests that policies are necessary to control the release of fry of this exotic salmonid in the Andes region.
How Does Pedestrian-Driver Behavior Influence in the Number of Crashes? A Michigan’s Case Study
Authors: Alhomaidat Fadi , Acosta-Rodriguez Lusanni 
Published: April 2021

Abstract
This study provides with a safety assessment of the pedestrian’s crash data in one of the largest cities of the state of Michigan, Grand Rapids. Crash data reviewed included a 9-year period between years 2010 and 2018. Crash clusters with largest number of accidents were selected to perform analysis based on the normalization of crash with population (using Census Bureau information). Geographic Information System (GIS) software was used to gather this data using a 250-feet buffer around the clusters. Also, GIS was used to identify the infrastructure design and locations nearby the studied area (e.g. schools and hospitals) to understand the crash environments. Observation of the associated factors with pedestrian crashes were studied at the location of interest. An analysis of all safety efforts was completed and a list of recommendations and possible implementation strategies (e.g. pedestrian countermeasures). Finally, it was found that four types of pedestrian crashes were most representative that crashes involved left-turning vehicle, crashes involved right-turn vehicle, crashed involved pedestrian in crosswalk and through traffic, and pedestrian were not cross at designated cross location
Intelligent Traffic Management: A Review of Challenges, Solutions, and Future Perspectives
Authors: Ravish Roopa , Swamy Shanta Ranga 
Published: April 2021

AbstractRecent years have witnessed a colossal increase of vehicles on the roads; unfortunately, the infrastructure of roads and traffic systems has not kept pace with this growth, resulting in inefficient traffic management. Owing to this imbalance, traffic jams on roads, congestions, and pollution have shown a marked increase. The management of growing traffic is a major issue across the world. Intelligent Transportation Systems (ITS) have a great potential in offering solutions to such issues by using novel technologies. In this review, the ITS-based solutions for traffic management and control have been categorized as traffic data collection solutions, traffic management solutions, congestion avoidance solutions, and travel time prediction solutions. The solutions have been presented along with their underlying technologies, advantages, and drawbacks. First, important solutions for collecting traffic-related data and road conditions are discussed. Next, ITS solutions for the effective management of traffic are presented. Third, key strategies based on machine learning and computational intelligence for avoiding congestion are outlined.Fourth, important solutions for accurately predicting travel time are presented.Finally, avenues for future work in these areas are discussed.
Pola Rekrutmen Bacaleg Perempuan Partai Keadilan Sejahtera pada Pemilu 2019 di Kota Banda Aceh
Authors: Aminah Aminah , Mulyani Sri , Ubaidullah Ubaidullah 
Published: April 2021

Since the reform era, women in Indonesia have begun to be reconsidered in various aspects, including being a part of policymakers and political contestation. It can be seen from implementing affirmative action policies, which obliges every political party to include the national level management and legislative candidates for at least 30% women. The recruitment process for legislative candidates interesting to discuss because the candidates not only from party cadres but including non-cadres. Especially women candidates that sometimes had no basis and experiences in politics also recruited. This study aims to determine the Partai Keadilan Sejahtera (PKS) recruitment patterns in determining women's candidates for the 2019 general election in Banda Aceh City. The research method used is descriptive qualitative. This study concluded that PKS uses a candidate's recruitment pattern with an open and closed system with the Barber model and always pays attention to each candidate's motivation sources and opportunities. AbstrakSejak era reformasi, perempuan di Indonesia mulai dipertimbangkan kembali dalam berbagai aspek, termasuk menjadi pembuat kebijakan dan kontestasi politik. Hal ini terlihat dari penerapan kebijakan affirmative action yang mewajibkan setiap parpol untuk mengikutsertakan pengurus tingkat nasional dan calon legislatif minimal 30% perempuan. Proses rekrutmen calon legislatif menarik untuk dibahas karena calon tidak hanya dari kader partai tapi termasuk non kader. Apalagi calon perempuan yang terkadang tidak punya dasar dan pengalaman di bidang politik pun ikut direkrut. Penelitian ini bertujuan untuk mengetahui pola rekrutmen Partai Keadilan Sejahtera (PKS) dalam penentuan calon perempuan pada pemilihan umum 2019 di Kota Banda Aceh. Metode penelitian yang digunakan adalah deskriptif kualitatif. Penelitian ini menyimpulkan bahwa PKS menggunakan pola rekrutmen calon dengan sistem terbuka dan tertutup model Barber dan selalu memperhatikan sumber motivasi dan peluang masing-masing calon.