bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stakeholders engagement as an important step for the long‐term monitoring of wild ungulate populations
Authors: Carvalho João , Leite Pedro , Valente Ana M. , Fonseca Carlos , Torres Rita T. 
Published: July 2021

Abstract
Monitoring trends in animal populations is essential for the development of appropriate wildlife management strategies. However, long‐term studies are difficult to maintain mainly due to the lack of continuous funding. In this scenario, the collaboration between local stakeholders and researchers can be a fruitful partnership to monitor game species for long periods and vast territories.
We present an experimental framework with the involvement of researchers, local hunters and game managers for the continuous monitoring of wild ungulate populations. By combining vehicle‐based counts with distance sampling techniques, we implemented and validated a sampling scheme able to provide demographic information for the effective management of wild ungulate populations. Here, we used an Iberian red deer (Cervus elaphus) population as a model.
The project implementation involved 30 participants including 24 stakeholders and 6 field technicians/data analysts with experience in monitoring wild ungulates. A total of eight teams covered 29 itineraries, synchronously, in two periods of ecological relevance for red deer, early summer and early autumn. Density estimates were consistent among sampling periods and characterized by acceptable coefficients of variation (approximately 20%). Our results prove that the application of the proposed framework is feasible (three to four itineraries per team), cost‐ and time‐effective (one week per sampling period) and produce population estimates fit for management. Being based on direct observations, the method would provide important demographic indicators (e.g. population density, age structure and fawn recruitment, and group size) about wild ungulate populations.
Apart from engaging interested stakeholders, the success of our proposal relies on three key actions including the theoretical and field instruction of participants, the definition of timely and unbiased survey designs and the maintenance of participants’ motivation. The implementation of rigorous and standardized sampling protocols is pivotal for data integration through time and space. In the absence of continuous funding, the voluntary collaboration between entities should be fostered to study and mitigate the potential threats to wild ungulate populations resulting from disease, unregulated hunting and environmental changes.
Design of a vehicle height and body posture adjustment hybrid automaton of electronically controlled air suspension
Authors: Hu Qiguo , Lu Wei , Jiang Jingzhen 
Published: July 2021

SummaryThe vehicle height and body posture adjustment of electronically controlled air suspension (ECAS) poses great challenges to hybrid control, since it involves discrete events of solenoid valve (SV) switching and dynamic evolutions of continuous variables. This article investigates in the modeling and verification of the vehicle height and body posture adjustment control system. A nonlinear mechanism model of the ECAS which considers the pneumatic characteristics of the SV is established. On the basis of mixed logical dynamical (MLD) modeling approach, a hybrid automaton describing on–off statuses transition equations of charging SV, discharging SV and four air spring SVs is established and then is compiled into the standard MLD model by using hybrid system descriptions language, realizing the coordinated control between the vehicle height and body posture by directly adjusting the SV on–off statuses. Simulation tests and bench tests are conducted and the results are presented to show how the designed hybrid automaton can be successfully applied to solve the difficulties that exist in the ECAS.
Plasmomechanical Systems: Principles and Applications
Authors: Koya Alemayehu Nana , Cunha Joao , Guerrero‐Becerra Karina Andrea , Garoli Denis , Wang Tao , Juodkazis Saulius , Proietti Zaccaria Remo 
Published: July 2021

AbstractExtreme confinement of electromagnetic waves and mechanical displacement fields to nanometer dimensions through plasmonic nanostructures offers unprecedented opportunities for greatly enhanced interaction strength, increased bandwidth, lower power consumption, chip‐scale fabrication, and efficient actuation of mechanical systems at the nanoscale. Conversely, coupling mechanical oscillators to plasmonic nanostructures introduces mechanical degrees of freedom to otherwise static plasmonic structures thus giving rise to the generation of extremely large resonance shifts even for minor position changes. This nanoscale marriage of plasmonics and mechanics has led to the emergence of a new field of study called plasmomechanics that explores the fundamental principles underneath the coupling between light and plasmomechanical nanoresonators. In this review, both the fundamental concepts and applications of plasmomechanics as an emerging field of study are discussed. After an overview of the basic principles of plasmomechanics, the active tuning mechanisms of plasmonic nano‐mechanical systems are extensively analyzed. Moreover, the recent developments on the practical implications of plasmomechanic systems for such applications as biosensing and infrared detection are highlighted. Finally, an outlook on the implications of the plasmomechanical nanosystems for development of point‐of‐care diagnostic devices that can help early and rapid detection of fatal diseases are forwarded.
A Ca‐Ion Electrochromic Battery via a Water‐in‐Salt Electrolyte
Authors: Tong Zhongqiu , Kang Tianxing , Wan Yingpeng , Yang Rui , Wu Yan , Shen Dong , Liu Shihao , Tang Yongbing , Lee Chun‐Sing 
Published: July 2021

AbstractMultivalent‐ion batteries with electrochromic functionality are an emerging green technology for development of low‐carbon society. Compared to Mg2+, Zn2+ and Al3+, Ca2+ has a low polarization strength similar to that of Li+, therefore Ca2+ for electrochromism and battery can avoid kinetic issues caused by other multivalent‐ions with high polarization strength. Here, by exploiting Ca‐ion carriers for electrochromism and a water‐in‐salt (WIS) Ca(OTF)2 electrolyte for the first time, a new and safe aqueous Ca‐ion electrochromic battery (CIEB) has been demonstrated. The WIS Ca(OTF)2 electrolyte demonstrates enhanced anion‐cation interactions and decreased water activity. Vanadium oxide (VOx) and indium hexacyanoferrate (InHCF) films are respectively developed as anode and cathode because of their stable and high‐rate Ca2+ insertion/extraction, as well as matched electrochromism. The CIEB demonstrates a stable and high‐rate capability, a high energy density of 51.4 mWh m−2 at a power density of 1737.3 mW m−2, and a greenish yellow‐to‐black electrochromism. The presented results are beneficial for understanding redox kinetics in WIS electrolytes, and inspire researches on batteries and electrochromism with multivalent‐ions.
Diagnostic Radionuclides Labeled on Biomimetic Nanoparticles for Enhanced Follow‐Up Photothermal Therapy of Cancer
Authors: Yi Xuan , Shen Mengling , Liu Xinpei , Gu Jingyu , Jiang Zewei , Xu Lixing , Yang Kai 
Published: July 2021

AbstractImaging‐guided local therapy is the most effective strategy to treat primary cancers in patients. However, the local therapeutic effect should be further improved under the premise of absence of induction of additional side effects. It would be meaningful to analyze the potential assistance of nuclear imaging to the follow‐up treatments. In this study,cancer‐targeted copper sulfide nanoparticles with 99mTc labeling (99mTc‐M‐CuS‐PEG) are prepared using‐cancer cell membranes as a synthesis reactor and applied for the potential single‐photon emission computed tomography/photoacoustic imaging‐guided and 99mTc‐amplified photothermal therapy of cancer. Owing to the homologous targeting capability of the cancer cell membrane, M‐CuS‐PEG selectively accumulates in homologous tumor sites. After labeling with 99mTc, M‐CuS‐PEG with a high near‐infrared light absorbance can realize bimodal imaging‐guided photothermal therapy of cancer. Furthermore, the labeled 99mTc significantly enhances the cell uptake of M‐CuS‐PEG by inducing G2/M arrest of the cell cycle, further improving the photothermal antitumor effect, which is positively correlated with endocytosis of the photothermal conversion reagent. Therefore, a novel cancer‐targeted theranostic nanoplatform is developed and it is revealed that the labeled 99mTc can not only guide but also amplify the subsequent therapy of cancer, providing a conceptual strategy for cancer theranostics with a high biosafety.
Triboelectric Nanogenerators for Self‐Powered Wound Healing
Authors: Xiao Xiao , Xiao Xiao , Nashalian Ardo , Libanori Alberto , Fang Yunsheng , Li Xiyao , Chen Jun 
Published: July 2021

AbstractWound healing, one of the most complex processes in the human body, involves the spatial and temporal synchronization of a variety of cell types with distinct roles. Slow or nonhealing skin wounds have potentially life‐threatening consequences, ranging from infection to scar, clot, and hemorrhage. Recently, the advent of triboelectric nanogenerators (TENGs) has brought about a plethora of self‐powered wound healing opportunities, owing to their pertinent features, including wide range choices of constitutive biocompatible materials, simple fabrication, portable size, high output power, and low cost. Herein, a comprehensive review of TENGs as an emerging biotechnology for wound healing applications is presented and covered from three unique aspects: electrical stimulation, antibacterial activity, and drug delivery. To provide a broader context of TENGs applicable to wound healing applications, state‐of‐the‐art designs are presented and discussed in each section. Although some challenges remain, TENGs are proving to be a promising platform for human‐centric therapeutics in the era of Internet of Things. Consequently, TENGs for wound healing are expected to provide a new solution in wound management and play an essential role in the future of point‐of‐care interventions.
Concurrent Enhancement of Conductivity and Stability in Water of Poly(3,4‐Ethylenedioxythiophene):Poly(Styrenesulfonate) Films Using an Oxetane Additive
Authors: Jorge Sara M. , Santos Luís F. , Galvão Adelino , Morgado Jorge , Charas Ana 
Published: July 2021

AbstractPoly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) is the most used conducting polymer in organic electronics and bioelectronics owing to its high conductivity combined with high optical transparency and availability as a stable colloidal aqueous dispersion, that can be processed as a conducting ink to produce thin and flexible films and electrodes. In this work, water‐resistant films of PEDOT:PSS showing enhanced conductivity are prepared by solely adding one reagent, 3‐methyl‐3‐oxetanemethanol, to PEDOT:PSS aqueous dispersions. The stability of the resultant thin films in water is attributed to the covalent cross‐linking of benzene rings anchored in PSS chains to polyether chains originated from the polymerization of oxetane groups, as indicated by NMR studies. A phase‐segregation within the PEDOT:cross‐linked PSS film is suggested to facilitate charge transport within the PEDOT network and to be at the origin of the improved conductivity. When immersed in water, the films exhibit increased water‐resistance towards resuspension and delamination and exhibit an increase of conductivity, by two to three orders of magnitude, depending on the used raw PEDOT:PSS formulation. The method described in this work is advantageous in originating water‐stable and highly conducting thin films of PEDOT:PSS as it does not involve high temperatures nor strong acids.
Hybrid Amino Acid‐TiO2 Materials with Tuneable Crystalline Structure and Morphology for Photocatalytic Applications
Authors: Sarigul Gamze , Chamorro‐Mena Ignacio , Linares Noemi , García‐Martínez Javier , Serrano Elena 
Published: July 2021

AbstractA method to produce hybrid organotitanias, both as thin films and suspensions, showing excellent photocatalyic activity in the degradation of organic dyes in aqueous solutions under visible light irradiation is disclosed. This method is based on the in situ incorporation of an amino acid, l‐tyrosine, during the synthesis of the titanias owing to its coordination and co‐condensation with the titania precursor under acidic conditions. This methodology allows the fine	‐tuning of their crystalline structure, size, and shape by simply varying the pH of the synthesis gel, leading to anatase nanoparticles of ≈5 nm and surface areas of ≈200 m2 g−1 at pH = 2.2, while highly crystalline rutile nanorods are formed at pH = 0. The incorporation of l‐tyrosine to both anatase nanoparticles and rutile nanorods enables these materials to absorb light in the visible range due to both the decrease in their band gap, as compared to the reference materials, and the presence of additional absorption edges at wavelengths higher than 400 nm. Consequently, the photocatalytic activity of both hybrid anatase nanoparticles and rutile nanorods exhibits a 120% enhanced photocatalytic efficiency, as compared to that of l‐Tyr‐free titanias and the commercial P25, which confirms their potential application in water remediation.
An Aqueous Anti‐Freezing and Heat‐Tolerant Symmetric Microsupercapacitor with 2.3 V Output Voltage
Authors: Jin Xuting , Song Li , Dai Chunlong , Xiao Yukun , Han Yuyang , Zhang Xinqun , Li Xiangyang , Bai Congcong , Zhang Jiatao , Zhao Yang , Zhang Zhipan , Jiang Lan , Qu Liangti 
Published: July 2021

AbstractSymmetric aqueous microsupercapacitors (MSCs) generally show a low working voltage (≤1 V) and narrow operating temperature window in the vicinity of 25 °C due to the poor temperature tolerance and instability of conventional aqueous electrolytes under high voltage. It is challenging to develop MSCs that can offer a high‐voltage output (>2 V) under complex ambient temperature. In this work, a symmetric MSC is fabricated by using the anti‐freezing and heat‐tolerant aqueous polyacrylamide polyelectrolyte (HVTT‐PAM‐10.5) and carbon nanotube microelectrodes, which achieves a record high output voltage of 2.3 V and the widest operating temperature window of −40 to 100 °C among the aqueous MSCs reported previously. It can deliver an ultrahigh areal energy density of above 4.9 μWh cm−2 at temperatures from −40 to 100 °C, outperforming the previous carbon‐based MSCs with aqueous electrolytes at room temperature. Additionally, even after 324 000 cycles at −40 °C and 10 000 cycles at 100 °C, the MSC still retains the high capacitance retention of 92.6% and 90.4%, respectively. Impressively, the HVTT‐PAM‐10.5 polyelectrolyte can also be paired with other electrode materials such as CNT/polyaniline to obtain the highest energy density of 48.6 μWh cm−2 among all symmetric/asymmetric MSCs with aqueous electrolytes.
Electrochemical Modulation of Carbon Monoxide‐Mediated Cell Signaling
Authors: Park Jimin , Zeng Joy S. , Sahasrabudhe Atharva , Jin Kyoungsuk , Fink Yoel , Manthiram Karthish , Anikeeva Polina 
Published: July 2021

AbstractDespite the critical role played by carbon monoxide (CO) in physiological and pathological signaling events, current approaches to deliver this messenger molecule are often accompanied by off‐target effects and offer limited control over release kinetics. To address these challenges, we develop an electrochemical approach that affords on‐demand release of CO through reduction of carbon dioxide (CO2) dissolved in the extracellular space. Electrocatalytic generation of CO by cobalt phthalocyanine molecular catalysts modulates signaling pathways mediated by a CO receptor soluble guanylyl cyclase. Furthermore, by tuning the applied voltage during electrocatalysis, we explore the effect of the CO release kinetics on CO‐dependent neuronal signaling. Finally, we integrate components of our electrochemical platform into microscale fibers to produce CO in a spatially‐restricted manner and to activate signaling cascades in the targeted cells. By offering on‐demand local synthesis of CO, our approach may facilitate the studies of physiological processes affected by this gaseous molecular messenger.
Preparation of Pd/PANI/ITO composite electrode and its degradation of tetracycline wastewater
Authors: Zhang Jian , Jiang Yuting , Wang Ziyi , Yang Xue , Zhang Mingrui , Wang Bing , Zhang Lanhe , Li Zheng , Liang Zilong , Liu Congze , Wu Hao 
Published: July 2021

AbstractIn order to treat antibiotics organic pollutants in the water environment, the Pd/PANI/ITO composite electrode was prepared by the galvanostatic electrodeposition method in this paper. The surface morphology and electrocatalytic activity of the electrode were analyzed and tested. Using the degradation rate of electrocatalytic tetracycline wastewater as an indicator, the optimal parameter conditions for preparing the composite electrode were screened out: the optimal deposition current of PANI was 2 mA, and the deposition time was 10 min. The optimal deposition current for Pd is 2 mA, and the deposition time is 10 min. The optimal current for the degradation of tetracycline wastewater is 10 mA, and the relationship between the degradation current and the degradation time conforms to the pseudo‐first‐order reaction kinetics. The existence of ·OH in the degradation process of tetracycline was verified by the coumarin fluorescence detection technology. Finally, the degradation process of tetracycline wastewater is analyzed. The results show that the intermediate products produced during the degradation of tetracycline are gradually cleavage of tetracycline molecules, and they are eventually converted into CO2 and H2O.
Identification of nonlinear system composed of parallel coupling of Wiener and Hammerstein models
Authors: Brouri Adil , Kadi Laila , Lahdachi Kenza 
Published: July 2021

AbstractIn this paper, a new method for the identification of nonlinear system composed by the Wiener and Hammerstein models connected in parallel is presented. This block‐oriented nonlinear system is a more general nonlinear model than Wiener and Hammerstein ones. The proposed nonlinear structure can easily describe the Wiener and Hammerstein models. Then, most of existing works are focused on the identification of one of the two models or the cascade connection of these two models. In this study, the parameters identification of linear and nonlinear blocks can be performed using one stage. Then, simple sine or multi‐sine waves were applied to the system input. Unlike several other methods, the linear elements can be parametric or not.
Adaptive output feedback control for a class of switched stochastic nonlinear systems under event‐triggered mechanism
Authors: Yuan Manman , Zhai Junyong 
Published: July 2021

AbstractThis article investigates the adaptive output feedback control problem for a class of switched stochastic nonlinear systems via an event‐triggered strategy. By virtue of the dynamic gain technique, a novel event‐triggered adaptive output feedback controller is designed. It is proved that all states of the closed‐loop system are globally asymptotically stable in probability. Two examples are presented to verify the effectiveness of the proposed scheme.
Has tumor doubling time in breast cancer changed over the past 80 years? A systematic review
Authors: Dahan Meryl , Hequet Delphine , Bonneau Claire , Paoletti Xavier , Rouzier Roman 
Published: July 2021

AbstractOver the past century, epidemiologic changes and implementation of screening may have had an impact on tumor doubling time in breast cancer. Our study was designed to evaluate changes in tumor doubling time in breast cancer over the past 80 years. A systematic review of published literature and meta‐regression analysis was performed. An online electronic database search was undertaken using the PubMed platform from inception until June 2020. All studies that measured tumor doubling time in breast cancer were included. A total of 151 publications were retrieved. Among them, 16 full‐text articles were included in the qualitative analysis. An exponential growth model was used for quantitative characterization of tumor growth rate. Tumor doubling time has remained stable over the past 80 years. Recent studies have not only identified “fast growing tumor” (grade 3, human epidermal growth factor receptor 2‐positive, triple‐negative, or tumor with an elevated Ki‐67) but also “inactive breast cancer” feeding the ongoing debate of overdiagnosis due to screening programs. The stability of tumor doubling time over the past 80 years, despite increasing and changing risk factors, supports the validity for our screening guidelines. Prospective studies based on more precise measurement of tumor size and adjustment for tumor characteristics are necessary to more clearly characterize the prognostic and predictive impact of tumor doubling time in breast cancer.
Significantly high expression of NUP37 leads to poor prognosis of glioma patients by promoting the proliferation of glioma cells
Authors: Liu Zhendong , Wang Hongbo , Jia Yulong , Wang Jialin , Wang Yanbiao , Bian Lu , Liu Binfeng , Lian Xiaoyu , Zhang Bo , Ren Zhishuai , Zhang Wang , Dai Weiwei , Gao Yanzheng 
Published: July 2021

AbstractBackgroundThe carcinogenic effect of NUP37 has been reported recently in a variety of tumors, but its research in the field of glioma has not been paid attention. The main purpose of this study is to reveal the relationship between NUP37 and prognosis or clinical characteristics of glioma patients.MethodsFirst, as a retrospective study, this study included thousands of tissue samples based on a variety of public databases and clinicopathological tissues. Second, a series of bioinformatics analysis methods were used to analyze the NUP37 and glioma samples from multiple databases such as the CGGA, TCGA, GEO, HPA, and GEPIA. Third, to analyze the relationship between the expression level of NUP37 in tumor tissues and cells and a variety of clinical prognostic molecular characteristics, whether it can be an independent risk factor leading to poor prognosis in glioma and whether it has clinical diagnostic value; GSEA was used to analyze the cancer‐related signaling pathways that may be activated by high expression of NUP37. Fifth, CMap was used to analyze small molecule drugs that may inhibit NUP37 expression. Finally, the meta‐analysis of thousands of tissue samples from seven datasets and cell proliferation and migration experiments confirmed that NUP37 has a malignant effect on glioma.ResultsNUP37 is highly expressed in glioma patient tissues and glioma cells, significantly correlates with reduced overall survival, and may serve as an independent prognostic factor with some diagnostic value. Silencing NUP37 suppresses malignant biological behaviors of glioma cells. 4 small molecule drugs that had potential targeting inhibitory effects on NUP37 overexpression.ConclusionsThis study demonstrates for the first time a malignant role of NUP37 in glioma and provides a vision to unravel the complex pathological mechanisms of glioma and a potentially valuable biomarker for implementing individualized diagnosis and treatment of glioma.