bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distal sacrectomy for recurrent rectal cancer
Authors: Kernychnyi V.V. , Li B.E. 
Published: December 2021

Summary. Surgical treatment of recurrent rectal tumors is a challenge for cancer surgeons. Due to the high risk of intraoperative and postoperative complications, such tumors are often considered inoperable. We present a clinical case of 56-years-old male patient with local recurrence and pathological fracture of the sacrum at S5 level to whom en-bloc distal sacrectomy was performed. Such surgical technique for recurrence of rectal cancer provides significant improvement in local and general condition and creates a favorable prognosis for the patient’s survival, which is demonstrated by the described clinical case.
Tumor-infiltrating lymphocytes as easily accessible prognostic tool in adenocarcinoma of the colon
Authors: Zakhartseva L. , Shkurupii B. 
Published: December 2021

Summary. Aim: To determine the prognostic value of tumor-infiltrating lymphocytes (TILs) in colon adenocarcinomas. Materials and Methods: The study was performed on 180 paraffin blocks of operation material from patients diagnosed with adenocarcinoma of the colon, treated at the Kyiv City Oncology Center in 2013–2018. TILs were counted on histological slides stained with hematoxylin-eosin. By TILs count percentage in tumor slides, the samples were divided into three groups: 0–9% TILs (n = 65); 10–39% TILs (n = 79); and > 40% TILs (n = 36). Results: Kaplan — Meyer estimate showed that the difference in overall survival between groups was significant (p = 0.001). Multivariate Cox’s proportional hazard regression model analysis evidenced on significantly better overall survival rates in groups with moderate TILs percentage (hazard ratio 0.54, 95% CI 0.30–0.97, p = 0.042) and high TILs percentage (hazard ratio 0.36, 95% CI 0.13–0.99, p = 0.049), respectively, as compared with low TILs percentage group. Conclusion: TILs content can be considered as an independent prognostic factor for colon adenocarcinoma and used as an additional tool in routine practice of pathologists.
Ukrainian prospective study in patients with T-cell non-Hodgkin lymphomas
Authors: Kriachok I. , Shudrak N. , Tytorenko I. , Stepanishyna Ya. , Martynchik A. , Aleksik O. , Novosad O. , Kadnikova T. , Pastushenko Ya. , Kyschevoy E. , Shokun N. 
Published: December 2021

Summary. Background: T-cell lymphoma (TCL) is a heterogeneous group of lymphoproliferative diseases that account for 10–15% of all non-Hodgkin lymphomas. The aim of the study was to analyze the incidence of TCL in Ukraine, distribution according to subtypes and to assess the results of treatment of patients with TCL depending on lymphoma subtype and clinical-and-laboratory risk factors. Patients and Methods: Data from 70 patients with TCL were analyzed from February 2018 to May 2021. T-cell lymphoid neoplasms were diagnosed according to the 2016 WHO classification. The patients were divided into 4 groups: 1st (A) — leukemic forms (n = 13) (received SMILE or HyperCVAD +/- auto/alloSCT); 2nd (B) — nodal T-cell lymphomas (n = 43) (CHOP-like regimens); 3rd (C) — cutaneous T-cell lymphomas (n = 9) (PUVA therapy, interferon, and methotrexate); 4th (D) — extranodal T-cell lymphomas (n = 5) (CHOP-like regimens). The response was determined according to the Lugano 2014 criteria. Results: According to the study results, 5–6% of all non-Hodgkin lymphoma registered in Ukraine in 2018–2020 were T-cell lymphomas. The most common subtype was peripheral TCL (61%). In the studied groups of TCL patients, the overall response rate was 50% (n = 35). 2-years event-free survival rate was 62.27%. 2-years overall survival rate was 65.76%. 18-month progression-free and overall survival in group B was higher versus groups A, C and D. The factors of unfavorable prognosis were bone marrow involvement and the expression of Ki67 > 65% (p = 0.03 and p = 0.006, respectively). Conclusions: Histologic subtype of T-cell non-Hodgkin lymphoma influence the treatment outcome. The best overall response rate, overall survival rate, progression-free survival were in group of patients with nodal T-cell non-Hodgkin lymphomas, the worst — in patients from leukemic group. Poor prognostic factors are bone marrow involvement, and Ki-67 expression > 65%.
Pengaruh Selfie-Liking dan Penyesuian Diri terhadap Prestasi Belajar Siswa
Authors: Ilyas Sabrida M. , Fitria Syiva 
Published: December 2021

Self-liking behavior that has become a lifestyle for teenagers who are active users of social media in the technology era has the potential to cause a decrease in learning achievement which is part of the mastery of knowledge over skills from student learning outcomes.However, empirical studies that explore self-adjustment in learning for adolescents with selfie-liking behavior have not been widely studied. In this study, the researchers aimed to determine the causal relationship between selfie-liking and self-adjustment in learning with high school student achievement. Data were collected from 223 (male=29.6%, female=70.4%) samples aged 16-17 years from three public high schools in Aceh Tamiang. The instrument used in this study were selfie-liking scale and self-adjustment in learning scale. The achievement was measured by using report score.The results of the regression analysis showed that there was no significant collective effect between selfie-liking and self-adjustment in learning achievement (R² = 0.017; F(2.220) = 1.942; p = .146). Partial regression showed that individually, self-liking was not significant in predicting learning achievement (β = -, 045; p = .529), while self-adjustment in learning was a significant predictor of learning achievement (β = ,142; p = . 005). Based on the above research, guidance and counseling teachers are expected to be able to provide preventive counseling services for the effect of excessive selfie like and provide guidance to subject teachers that although students in online learning still display selfie photos, it is not a negative impact on their mental and achievement.
Parametrical Synthesis of Radio Devices with the Set Quantity of Identical Cascades for Inclusion Variants of Jet Two-port Networks between a Nonlinear Part and Loading
Authors: Golovkov A. A. , Fomin A. V. 
Published: December 2021

Introduction. The ability to analytically determine some parameters of various radio devices, which are optimal according to the criterion of providing the set values of the modules and phases of transfer functions at the required number of frequencies, significantly reduces the time for numerical optimization of the rest of the parameters according to the criterion of forming the required frequency response and frequency response in the frequency band. Until now, such problems with respect to radio devices have been solved only for one stage of the "nonlinear part – matching device" or "matching device – nonlinear part" type. As a matching device, reactive, resistive, complex, or mixed quad-poles were used.Aim. Development of algorithms for parametric synthesis of radio devices with an arbitrary number of identical cascades of the "nonlinear part – matching reactive quadrupole" type according to the criterion of ensuring the specified frequency characteristics. Non-linear parts are represented as a non-linear element and parallel or serial current or voltage feedback.Materials and methods. Four-pole theory, matrix algebra, decomposition method, method of synthesis of microwave control devices, numerical optimization methods.Results. Systems of algebraic equations are formed and solved. Models of optimal quadrupole conductors are obtained in the form of mathematical expressions for determining the relationships between the elements of their classical transmission matrix and for finding the frequency dependences of the resistances of two-pole conductors.Conclusion. It is shown that the frequency characteristics of the studied radio devices from the same stages are identical or similar to the frequency characteristics of radio devices from the same stage, but with the signal source and load resistances changed in a certain way. Such schemes are called equivalent. A comparative analysis of the theoretical results (frequency response and frequency response of radio devices) obtained by mathematical modeling in the "MathCad" system, and the experimental results obtained by circuit modeling in the "OrCAD" and "MicroCap" systems, shows their satisfactory agreement.
Determination of Parameters of Electronic Devices by the Method of Passive Radio-Sensor Technical Diagnostics
Authors: Boikov K. A. 
Published: December 2021

Introduction. Technical diagnostics (TD) as a nascent discipline is rapidly developing in the field of both software and hardware. Modern TD methods, such as vibrometry, thermal control, JTAG testing and optical control, either exhibit high inertia, consume processor time, require suspension of the electronic device, or demand a galvanic contact with the study object, which is often unacceptable. These disadvantages can be eliminated by passive radio-sensor TD. To date, little information has been published on the parameters of electronic devices provided by this method.Aim. Determination of the parameters of electronic devices, the assessment of which can be provided by passive radio-sensor TD.Materials and methods. Signal radio profiles were obtained experimentally using metrological equipment and software-numerical methods for modeling radio wave processes. The parameters of the signal radio profile were calculated by a mathematical method for solving differential equations.Results. The main principles and results of radio-sensor TD, as well as the simplest toolkit, are shown. An equation is obtained for the signal radio profile emitted by the electronic unit of the device, as well as an expression for its free components. An approach for assessing the TD correctness based on the number of free components of the received signal radio profile and the reference is described. The possibility of obtaining information about temperature, voltage drop, speed of emitting nodes, as well as the state of its components and modes of operation of p–njunctions is demonstrated. It is shown that this information is carried by the parameters of the basic equation for the signal radio profile.Conclusion. The derived basic equation allows a non-contact, remote passive radio-sensor TD to be conducted by correlation analysis of the received signal, providing a detailed examination of malfunctions in each electronic unit. The described TD method based on the presented parameters is promising for assessing the technical state of electronic devices.
Feasibility Assessment of Using Smart Trackers in Telemedicine Systems to Remotely Monitor the Overall Health of Patients in Real-Time
Authors: Pospelova I. V. , Cherepanova I. V. , Bragin D. S. , Serebryakova V. N. 
Published: December 2021

Introduction. The development of telemedicine systems intended to remotely monitor the health status of patients constitutes one of the most promising areas of contemporary science. Particularly relevant is the use of such systems to track the health of surgically treated patients. Since such patients are mobile, sensors measuring vital signs should not cause any discomfort in regular use. Thus, wearable smart trackers can be used for these purposes.Aim. The paper aims to study the possibility of using smart trackers in a telemedicine system for monitoring patient health.Materials and methods. In the study, a series of measurements was performed using GSMIN WR 41 smart bracelets in order to estimate their accuracy when measuring pulse, blood pressure, and oxygen saturation for different research subjects at rest and during intense physical exercises. In addition, the average measurement interval of the smart bracelet was determined; the operation of the smart bracelet in the telemedicine system for monitoring vital signs was considered.Results. The studies show that an average error in the measurement of vital signs (except for systolic pressure) using the smart bracelet does not exceed 10 %. In order to avoid the high error in measuring systolic pressure, an algorithm for assessing the general health of patients was developed. In addition, it is shown that the smart bracelet can detect an abrupt change in the vital signs of patients, with the average time of their measurement and data transmission to the server of the telemedicine system coming to 45 seconds.Conclusion. The study results indicate that smart bracelets can be used to remotely monitor the health of patients in real-time. These findings are confirmed by the telemedicine system designed on the basis of the smart bracelets considered in the paper.
Risk and Solution of English Language E-Textbook for Non-English Study Program Students
Authors: Gumartifa Asti , Yuliani Sri , Marliasari Sherly 
Published: December 2021

Abstract: E-textbooks are also referred to as electronic books, printed downloads, or internet sources. A textbook is an ideal example of technology in active learning for university students. E-textbooks are becoming more great choice than paper textbooks. In several academic institutes at a campus like the University of Muhammadiyah Palembang, where every lecturer is allowed to have a personal laptop. Thus, it's critical to look into how e-textbooks are adopted and how they might alter students' learning processes. The purpose of this study is to see what the risks of learning are and how to optimize the solution for learning and using English e-textbook for non-English study program students. This research’s novelty provides solutions and even optimizations related to the existing advantages and disadvantages specifically faced by non-English department students in learning English through e-textbooks. The solutions and optimizations are discussed descriptively into the modern approach and innovative technology. Furthermore, this research is beneficial for students to learn English for specific purposes.
Keywords: E-textbook, risk, helpful, technology, learning
Histological examination of cranial synchondroses as functionally significant elements in the cranial osteopathic concept
Authors: Osipov V. A. , Pastukhov A. N. , Kurbatov O. I. , Potekhina Yu. P. 
Published: December 2021

Introduction. In recent decades, medical science has accumulated convincing evidence of the fact that the normal activity of a human brain depends on the functional integration of its vascular system, a circulation system of cerebrospinal fluid and biomechanical features of a skull, forming a single structural and functional system.The aim of the study is to research the histological structure of functionally significant cranial synchondroses in the middle and elderly age group, to find possible points of osteopathic influence application in their structure. Materials and methods. The study was performed on cadaver material of 27 persons (7 men — 26 %, 20 women — 74 %) who died at the age from 49 to 66 years (57,5±5,3 years) from various somatic pathologies, but had no history of craniocerebral injuries with fractures of osseous structures. Small bone fragments with sutures of interest/synchondroses (spheno-occipital synchondrosis, petro-jugular synchondrosis, sphenopetrosal synchondrosis) were subjected to standard histological processing followed by microscopy.Results. Evaluating histological specimens of spheno-occipital synchondrosis, we observed the similar pattern: highly mineralized tissues at the edges of the bodies of the sphenoid and occipital bones were connected without elements of cartilagi-nous or connective tissue. In all cases, no fibrous or nerve tissue elements were found during the in situ immunohistochemical reactions. Reactions with the CD34 antibody mark multiple vessels of the Volkmann's or Haversian canals. Evaluating histological specimens of petro-jugular and sphenopetrosal synchondroses, we found the presence of cartilage tissue in the suture in the form of small islands of various sizes (from 20 to 120 microns) with signs of degeneration and a small number of remained chondrocytes. When evaluating specimens with immunohistochemical reactions with antibodies against the S100 protein, no elements of the nervous tissue were detected.Conclusion. Spheno-occipital synchondrosis has a temporary nature. With age, its cartilaginous tissue is replaced by osseous one. According to the histological structure, sphenobasilar synchondrosis demonstrates the complete absence of a cartilaginous component in the middle and elderly age groups. Petro-jugular and sphenopetrosal synchondroses retain the cartilaginous component in their suture throughout lifetime. During histological examination of the petro-jugular and sphenopetrosal synchondroses, the cartilaginous component is represented by variety of small islands. In all synchondroses, there is an absence of vascular and nervous components. At the same time, we revealed the presence of a prominent vascular bed in the bone tissue. The fact requires emphasizing the importance of liquid potency and elastic component in cartilaginous and osseous tissues as an application point for osteopathic techniques.
Experience in the use of tissue flossing for the prevention and treatment of muscle cramps
Authors: Vasilevich S. V. , Zaltcman P. L. 
Published: December 2021

Introduction. Cramps are sudden, involuntary, painful tonic muscle spasms of individual muscles or muscle groups lasting from several seconds to several minutes. It occurs in patients of different age categories with a frequency of up to 37 %. Tissue flossing (flossing, voodoo flossing) is an effect on the musculature, tendons, fascia (myofascial structures) of the extremities with the help of a special elastic band circularly wound on the limb, and subsequent physical exercises in this condition in order to improve blood circulation in the limb segment, increase tissue mobility, elasticity and extensibility of muscle-fascial structures. Tissue flossing can help to increase the volume of movements in the joints, reduce pain and increase flexibility.The aim to study the effects of tissue flossing on the frequency and intensity of manifestations of cramps. Materials and methods. The publication was based on the materials obtained during the observation of 7 patients with cramps. The aggressive nature of the muscle spasms forced them to seek medical help. In order to assess the effect on the frequency and intensity of cramps, patients underwent circular winding of an elastic band on a limb segment (tissue flossing) in which cramps occurred, followed by physical exercises (mainly flexion and extension at a pace of one movement per second) without additional load (with their weight) for 1 minute. Then the elastic band was removed and the patient continued to perform the same movements also for a minute with a frequency of one movement per second. Patients performed exercises 1-2 times a day for 5-14 days.Results. In five out of seven patients, cramps did not resume after the first use of tissue flossing. In two of the seven patients, cramps stopped after 7 days of exercise use. At follow-up in one (out of seven) patients, cramps resumed 2 months after the use of tissue flossing, but with a lower intensity. In the other six (out of seven) patients in the subsequent follow-up period (from 14 days to 6 months), cramps did not resume.Conclusion. According to the preliminary results of observations, it can be assumed that the tissue flossing method is effective for preventing cramps of various genesis as an independent and additional method of treatment.
ОСНОВНІ ПРИНЦИПИ ПРОФЕСІЙНОЇ ПІДГОТОВКИ МАЙБУТНІХ РЯТУВАЛЬНИКІВ
Authors: Коваль Мирослав , Коваль Ігор 
Published: December 2021

У статті аргументовано, що спеціальна освіта майбутніх рятувальників до діяльності в екстремальних умовах передбачає врахування методологічних ідей і вимог до організації освітнього процесу в закладах вищої освіти Державної служби України з надзвичайних ситуацій, що відображають сукупність принципів професійної підготовки. До основних принципів професійної підготовки, що необхідно реалізовувати у професійній підготовці фахівців служби цивільного захисту, віднесено принципи професійної спрямованості навчання, випереджального розвитку, фундаменталізації, інформатизації, неперервності й наступності. Усі зазначені принципи реалізуються в тісному взаємозв’язку, взаємозумовлюючи і продукуючи один одного.
Ключові слова: принципи професійної підготовки; професійна готовність; рятувальники; компетентність; інформатизація; безпека людини.
ОФІЦЕР СТРУКТУР МОРАЛЬНО-ПСИХОЛОГІЧНОГО ЗАБЕЗПЕЧЕННЯ ЯК СУБ’ЄКТ СПЕЦИФІЧНОЇ ВІЙСЬКОВО-ПРОФЕСІЙНОЇ ДІЯЛЬНОСТІ
Authors: Нехаєнко Сергій 
Published: December 2021

У статті аналізується педагогічна проблема військово-професійної діяльності офіцера структур морально-психологічного забезпечення як різновиду специфічної військово-професійної діяльності. Основним суб’єктом морально-психологічного забезпечення, як одного з видів всебічного забезпечення воєнної є офіцер структур морально-психологічного забезпечення, на якого у відповідності до визначених функціональних обов’язків покладаються завдання планування, управління, контролю ефективного управління та керівництва морально-психологічним забезпеченням, ухвалення виваженого та відповідного умовам виконання службово-бойових завдань рішення, прийняття на себе відповідальності за нього.
Особистість офіцера структур морально-психологічного забезпечення його професійна суб’єктність та його ставлення до військово-професійної діяльності є визначальною передумовою його успішності, що обумовлює роль офіцера як головного суб’єкта в системі такої винятково специфічної діяльності, як військова.
Враховуючи, що перед випускником Національного університету оборони України імені Івана Черняховського – офіцером структур морально-психологічного забезпечення постає проблема адекватного реагування на особистість військовослужбовців на етапі формування їх як професійних воїнів, перед якими постає проблема прийняття на себе нової ролі – солдата, виняткова роль в процесі формування морально-психологічного стану належить офіцеру структур морально-психологічного забезпечення, який керує цим процесом. Особливістю військово-професійної діяльності та особистості офіцера структур морально-психологічного забезпечення є його значимість для підлеглого особового складу.
Ключові слова: суб’єкт; діяльність; військово-професійна діяльність; специфічна діяльність; функції; офіцер; структури морально-психологічного забезпечення.