bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the effect of high-intensity interval training on macular microcirculation via swept-source optical coherence tomography angiography in young football players
Authors: Karaküçük Yalçın , Okudan Nilsel , Bozkurt Banu , Belviranlı Muaz , Tobakçal Fatih 
Published: September 2021

Purpose:
This study was conducted to evaluate the effect of high intensity interval training (HIIT) on macular microcirculation, measured by swept source optical coherence tomography angiography (ss OCTA) in young football players.

Methods:
Football players between 18–20 years old were included. After a detailed ophthalmological examination, physiological parameters, including height, body weight, body fat, systemic blood pressure, hematocrit values, oxygen saturation, and heart rate, were recorded. Intraocular pressure and ss OCTA parameters were measured one day before and the day after the high intensity interval training program using DRI OCT Triton (Topcon, Tokyo, Japan) between 11:00 am and 1:00 pm.

Results:
Fifteen participants completed the study. All were males with a mean age of 18.1 ± 0.4 years. Systolic and diastolic blood pressure and oxygen saturation did not change significantly (P > 0.05), while hematocrit levels increased remarkably (P = 0.049) after the HIIT program. Heart rates and intraocular pressure decreased (P = 0.003, P = 0.017, respectively). There was a significant increase in the central vessel density in deep capillary plexus (before: 18.7 ± 3.8%, after: 21.1 ± 4.5%) and central vessel density in choriocapillaris (before: 54.5 ± 2.8%, after 56.9 ± 2.2%) (P = 0.02, P = 0.02, respectively), although no changes were observed in other ss OCTA or in the central macular thickness and subfoveal choroidal thickness.

Conclusion:
A 6 week, high intensity interval training program with three exercise sessions per week seems not to alter mean superficial vascular densities, deep foveal avascular zone, and superficial foveal avascular zones, central macular thickness, or subfoveal choroidal thickness, while the central deep vascular density and central choriocapillaris vascular density increased remarkably among ss OCTA parameters.
A clinical study on the correlation between demodex infestation and ocular surface changes in patients with meibomian gland dysfunction
Authors: Pan Shuling , Chen Yan 
Published: September 2021

Purpose:
To observe the effect of demodex infection on the ocular surface changes of patients with meibomian gland dysfunction (MGD) and analyze the correlation between the number of demodex and the changes of the ocular surface.

Methods:
Hundred patients with MGD aged 18–70 years who visited the dry eye center of Shanghai Aier Eye Hospital were recruited. All patients were examined with in vivo confocal microscopy to quantify the demodex and divided them into two groups (demodex negative group and demodex positive group) according to the number of demodex mites. The subjects underwent questionnaires of ocular surface disease index (OSDI) and a series of examinations. Parameters including the OSDI score, fluorescein tear film break-up time (FBUT), meibum quality, meibum gland expressibility, meibomian gland dropout (MG dropout), and ocular redness were recorded and compared between the two groups. The correlation between the number of demodex and the ocular surface changes was further analyzed.

Results:
Among 100 patients, 51 were positive for demodex. The demodex-positive group showed significantly increased scores of OSDI (24.41 ± 3.43 vs 20.98 ± 2.31, P = 0.00), ocular redness score (1.38 ± 0.46 vs 1.00 ± 0.30, P = 0.00), and MG dropout (3.00 ± 1.13 vs 2.18 ± 0.64, P = 0.00) and decreased FBUT (6.40 ± 1.63 vs 6.54 ± 1.83, P = 0.00), compared to the demodex-negative group. A significant correlation was noted between the number of demodex and OSDI, ocular redness, and FBUT.

Conclusion:
Ocular demodex infestation might play a role in the ocular surface discomfort, inflammation, and meibomian gland dropout in MGD patients. It is necessary to pay attention to the examination and treatment of demodex mite in patients with MGD.
Comparison of single-step renal dilatation and serial renal dilatation in percutaneous nephrolithotomy
Authors: Sharma Amit , Parab Sandesh , Goyal Gaurav , Patel Ajit , Andankar Mukund , Pathak Hemant 
Published: September 2021

Background:
Access to the pelvi-calyceal system and subsequent dilatation of the tract are among the initial important steps in percutaneous nephrolithotomy (PCNL). In this study, we share our experience with single-step renal dilatation when compared to multiple serial renal dilatation in PCNL.

Materials and Methods:
This is a retrospective study wherein 35 patients who underwent PCNL by single-step renal dilatation by appropriate size Amplatz Dilator were compared with 35 patients who underwent multi-step serial renal dilatation using serial metallic Alken dilators. These patients were analyzed on the basis of demographic profile, total intra-operative time, fluoroscopic time, intra-operative and postoperative complications, stone clearance, requirement of blood transfusion, duration of hospital stay, and follow-up.

Results:
There were no significant differences in the demographic profile among the patients in these two groups. The mean total operative duration and fluoroscopic duration were less in single step renal dilatation group, and these have been found to be statistically significant (P < 0.05). There were no statistically significant differences in the rates of other complications – incomplete stone clearance, bleeding and hematoma formation, requirement of blood transfusion, duration of hospital stay, and follow-up.

Conclusion:
Operative duration and rate of radiation exposure are significantly less in PCNL by single-step renal dilatation; however, there is no statistically significant difference in the rates of other complications.
The accuracy of computed tomography in the diagnosis of upper urinary tract urothelial carcinoma in correlation with the final histopathology
Authors: Abouelkheir Rasha T. , Elawdy Mohamed Mohamed , Taha Diaa Eldin , El-Hamid Mohamed Abd , Osman Yasser , El-Diasty Tarek 
Published: September 2021

Introduction:
Because the reports in the literature of radiologic investigations for upper tract urothelial cancer (UTUC) are limited by the number of patients, and included patients with different pathologies, we aimed to study the overall accuracy of computed tomography (CT) in the diagnosis of UTUC and their accuracy on predicting tumor location.

Methods:
A retrospective review from 1990 to 2017 included patients who were treated for UTUC. Unenhanced CT scan was obtained first using Multi-Detector Computed Tomography (MDCT, Philips Medical Systems), then nonionic contrast medium, containing 350 mg iodine/ml was injected at 4 mL/s. Analysis was performed using SPSS®.

Results:
Of 275 patients, complete data on CT was available on 270 (98%) patients. CT reported only two false positive and six false negative results and the overall accuracy was 96-97%. In comparison to the final pathological reports, CT/CTU detected 85% of the tumor location of in the renal pelvic and 50% of the calyceal tumors. In ureteric tumors, they detected distal (66/71= 93%) more than proximal ureteric tumors (60%).

Conclusion:
In our cohort, CT/ CTU has a high overall accuracy (97%) in diagnosing UTUC, capability to well visualize tumors of distal ureter and renal pelvis, but could miss calyceal tumors. The matter to rely only on CT without ureteroscopic biopsy in the diagnosis of UTUC especially if radical surgery is planned needs further prospective studies.
Butantã versus mariante
Authors: Canez Anna Paula Moura , Brino Alex Carvalho , De Avila Débora Saldanha , Knies Carolina Gottert 
Published: September 2021

Trata-se de um estudo com foco no projeto como investigação de duas casas construídas em São Paulo, uma repetidamente identificada como pertencente à Escola Paulista Brutalista e a outra celebrada em diversas e recentes publicações como exemplar no universo contemporâneo da arquitetura brasileira, construídas em momentos muito distintos da nossa história. A primeira é a chamada Casa Butantã (1964-1966), pois situada no bairro que lhe deu o nome, de Paulo Mendes da Rocha - em realidade, duas casas lado a lado, uma realizada para o próprio arquiteto e a outra para a sua irmã, e a segunda é a casa Mariante, projetada 37 anos depois (2001-2002) por Angelo Bucci, do SPBR Arquitetos, e Marta Moreira, Fernando de Mello Franco e Milton Braga, do MMBB Arquitetos, localizada dentro de um condomínio fechado, distante 40 quilômetros do centro de São Paulo. O objetivo do trabalho foi buscar decifrar as duas obras escolhidas para análise, compreendê-las através de descrições apoiadas graficamente em material produzido pelo grupo de trabalho, cujo foco principal foi o saber propriamente arquitetônico. Revelar escolhas e descobrir o conceito, partindo do que suscitam através do redesenho e da revisão da bibliografia existente e, aí sim, compará-las com o propósito de apontar caminhos convergentes e divergentes.

This is a study focusing on the project as an investigation of two houses built in São Paulo, one repeatedly identified as belonging to the Paulista Brutalist School and the other celebrated in several recent publications as exemplary in the contemporary universe of Brazilian architecture, built at very different times in our history. The first one is the so-called Butantã House (1964-1966), since it is located in the neighborhood that gave it its name, by Paulo Mendes da Rocha - in reality, two houses side by side, one built for the architect himself and the other for his sister, and the second is the Mariante house, designed 37 years later (2001-2002) by Angelo Bucci, from SPBR Arquitetos, and Marta Moreira, Fernando de Mello Franco and Milton Braga, from MMBB Arquitetos, located in a private condominium 40 kilometers from downtown São Paulo. The objective of the work was to decipher the two works chosen for analysis, to understand them through descriptions graphically supported by material produced by the working group, whose main focus was the architectural knowledge itself. Revealing choices and discovering the concept, starting from what they raise through the redesign and the revision of the existing bibliography and, then, comparing them with the purpose of pointing out convergent and divergent paths.
Statins as anti-pyroptotic agents
Authors: Khalifeh Masoomeh , Penson Peter , Banach Maciej , Sahebkar Amirhossein 
Published: September 2021

IntroductionPyroptosis is a regulated form of cell death, which is often a consequence of the activation of inflammatory caspases.Material and methodsAppropriate inflammatory responses and the induction of pyroptosis enhance the clearance of pathogens and increase innate immunity.ResultsHowever, excessive pyroptosis contributes to a hyperinflammatory response and aggravates tissue damage, thereby causing inflammatory diseases. There have been recent reports on the modulation of pyroptosis by statins, which may explain part of the pleiotropic actions of these drugs in inflammatory diseases and cancer.ConclusionsHerein, the extant evidence for the potential value of statins in targeting pyroptosis in various diseases is reviewed.
Towards a comprehensive assessment system of local government fiscal health
Authors: Kooij Jurriaan , Groot Tom 
Published: September 2021

Understanding fiscal health, also commonly referred to as financial condition, is key to sound decision making and the proper functioning of local government. Nonetheless there is no agreed upon way to measure fiscal health. We argue that the use of a conceptual framework is essential in furthering our understanding of measuring and assessing local government fiscal health. In this study we offer a framework and a set of financial accounting indicators visualizing fiscal health on the short and long term, taking into account the existing liabilities and local government obligations towards its constituents. The study draws on the theoretical and empirical analysis of corporate bankruptcy prediction models and local government fiscal distress models. We develop a possible comprehensive set of fiscal health indicators and compare it with existing empirical studies of local government fiscal health.
The model captures current performance in four solvency dimensions (cash, budget, service-level and long term) and allows for predictions of future performance, taking into account risks (predictors of possible future financial stress) and capabilities (opportunities to strengthen future financial health). We tested our model by reviewing 33 empirical studies and found that we could allocate all indicators used to the dimensions of our framework. No empirical study appears to address all dimensions. The selection of performance dimensions is partly driven by the studies’ research objectives.
Effect of high-concentrate diets with calcium lignosulfonate and cottonseed processing method on quantitative traits and non-carcass components of feedlot cull ewes
Authors: Viana Pablo Teixeira , de Carvalho Gleidson Giordano Pinto , Viana Mirelle Costa Pignata , de Assis Dallyson Yehudi Coura , de Figueiredo Mauro Pereira , Cirne Luís Gabriel Alves , Figueredo Jennifer Souza , Sousa Lorena Santos , de Santana Júnior Hermógenes Almeida , Pina Douglas dos Santos , Alba Henry Daniel Ruiz 
Published: September 2021

Abstract. This study examined the effects of cottonseed processing form and
the inclusion of calcium lignosulfonate in high-concentrate diets for
feedlot cull ewes on carcass traits and non-carcass components. Thirty Santa
Inês cull ewes with an average body weight of 44.2 ± 5.2 kg and an
average age of 50 months were distributed into collective stalls in a
completely randomized design. The treatments consisted of diets including
whole cottonseed, crushed cottonseed, whole cottonseed treated with
lignosulfonate (100 g/kg, as fed), crushed cottonseed treated with
lignosulfonate (100 g/kg, as fed), and a control diet without cottonseed.
The experimental diets did not influence (P>0.05) average daily
weight gain (0.195 kg/day), slaughter weight (51.74 kg), or in vivo biometric and
on-carcass measurements. There was no difference (P>0.05) in
loin-eye area or subcutaneous fat thickness as evaluated in vivo by ultrasound.
There was no diet effect on hot carcass weight and yield (24.8 kg and
47.8 %), cold carcass weight and yield (24.2 kg and 46.8 %), or chilling
loss (2.1 %). Non-carcass components did not differ in response to the
diets (P>0.05). Dietary inclusion of calcium lignosulfonate
increases the proportions of udder and liver relative to empty body weight
(P<0.05). Neither the cottonseed processing method nor the
inclusion of calcium lignosulfonate in high-concentrate diets for cull ewes
affects their performance, biometric or morphometric measurements,
non-carcass components, or qualitative traits of their carcass.
Urban aerosol chemistry at a land–water transition site during summer – Part 1: Impact of agricultural and industrial ammonia emissions
Authors: Balasus Nicholas , Battaglia Jr. Michael A. , Ball Katherine , Caicedo Vanessa , Delgado Ruben , Carlton Annmarie G. , Hennigan Christopher J. 
Published: September 2021

Abstract. This study characterizes the impact of the Chesapeake Bay and associated meteorological phenomena on aerosol chemistry during the second Ozone Water-Land Environmental Transition Study (OWLETS-2) field campaign, which took place from 4 June to 5 July 2018. Measurements of inorganic PM2.5 composition, gas-phase ammonia (NH3), and an array of meteorological parameters were undertaken at Hart-Miller Island (HMI), a land–water transition site just east of downtown Baltimore on the Chesapeake Bay. The observations at HMI were characterized by abnormally high NH3 concentrations (maximum of 19.3 µg m−3, average of 3.83 µg m−3), which were more than a factor of 3 higher than NH3 levels measured at the closest atmospheric Ammonia Monitoring Network (AMoN) site (approximately 45 km away). While sulfate concentrations at HMI agreed quite well with those measured at a regulatory monitoring station 45 km away, aerosol ammonium and nitrate concentrations were significantly higher, due to the ammonia-rich conditions that resulted from the elevated NH3. The high NH3 concentrations were largely due to regional agricultural emissions, including dairy farms in southeastern Pennsylvania and poultry operations in the Delmarva Peninsula (Delaware–Maryland–Virginia). Reduced NH3 deposition during transport over the Chesapeake Bay likely contributed to enhanced concentrations at HMI compared to the more inland AMoN site. Several peak NH3 events were recorded, including the maximum NH3 observed during OWLETS-2, that appear to originate from a cluster of industrial sources near downtown Baltimore. Such events were all associated with nighttime emissions and advection to HMI under low wind speeds (< 1 m s−1) and stable atmospheric conditions. Our results demonstrate the importance of industrial sources, including several that are not represented in the emissions inventory, on urban air quality. Together with our companion paper, which examines aerosol liquid water and pH during OWLETS-2, we highlight unique processes affecting urban air quality of coastal cities that are distinct from continental locations.
Applicability of Landsat 8 thermal infrared sensor for identifying submarine groundwater discharge springs in the Mediterranean Sea basin
Authors: Jou-Claus Sònia , Folch Albert , Garcia-Orellana Jordi 
Published: September 2021

Abstract. Submarine groundwater discharge (SGD) has received increasing attention over the past 2 decades as a source of nutrients, trace elements and ocean pollutants that may alter coastal biogeochemical cycles. Assessing SGD flows and their impact on coastal marine environments is a difficult task, since it is not easy to identify and measure these water flows discharging into the sea. The aim of this study is to demonstrate the significant usefulness of the freely available thermal infrared (TIR) imagery of the Landsat 8 thermal infrared sensor (TIRS) as an exploratory tool for identifying SGD springs worldwide, from local to regional scales, for long-term analysis. The use of satellite thermal data as a technique for identifying SGD springs in seawater is based on the identification of thermally anomalous plumes obtained from the thermal contrasts between groundwater and sea surface water. In this study, we use the TIR remote sensing (TIR-RS) imagery provided by Landsat 8 at a regional scale and discuss the principle limiting factors of using this technique in SGD studies. The study was developed in karstic coastal aquifers in the Mediterranean Sea basin during different seasons and under diverse
meteorological conditions. Although this study demonstrates that freely available satellite TIR remote sensing is a useful method for identifying coastal springs in karst aquifers both locally and regionally, the limiting factors include technical limitations, geological and hydrogeological
characteristics, environmental and marine conditions and coastal geomorphology.
منہجِ تفسیر ’’دروس القرآن الحکیم‘‘از مولانا سید شمس الحق افغانی ؒ
Authors: Bano Shazia , Hafiz Muhammad Aslam  
Published: September 2021

The cognizance of religion and the intellect of the Qur’an rests on the epexegesis of the Holy Qur’an. A large number of the people of Muslims Ummah have been absorbed in the epexegesis of the Holy Qur’an and they have left indelible marks in the history of the Holy Quran explanation. The Tafsir ‘‘Duroos ul Qur’an Al Hakeem’’ written by Syed Shams-ul-Haqq Afghani occupies an illustrious place in the epexegesis of the Holy Qur’an. Molana Afghani wrote the book "Uloom ul Qur’an" on the topic of Usool e Tafseer in a unique style.
In his tafsir, Molana Afghani had made the explanation of qur’anic verses according to principles of his book "Uloom ul Quran"
He endeavor to make the message of the Qur’an in scientific and modern way before the reciter of the Holy Qur’an by using different examples .He had keenly observed the bad conditions of the Muslims in his era and give the enticement the new generation to reform their problems in the light of Holy Qur’an.
A Sociological Study of Transgression of Basic Guarded Rights of Transgenders & Hurdles in Finding their Gender Identity in Socio-Cultural Context ( A Case Study of Segregated Localities of Multan)
Authors: Aslam Hina 
Published: September 2021

This article deals with the study of the problems faced by transgenders, in regards of their guarded rights being transgressed,both from the familial and socio-cultural context. This study is amid, to explore socio-cultural behavior of individuals who surround a trans either from his/her family or society. Questions have already emerged about sociological problems and cultural adjustment as a human being and its related casual factor related to a transgender. It is one of the emerging issues of our society that directly influences the identity of those people who are facing gender disapproval from their surroundings. This research work tried to discover the factors that influence the discrimination faced generally and particularly by trans. The article reveals the social and cultural norms that stigmatize socio-cultural exclusion of trans human beings from the society and how continuous banishment from society makes their life more tough after being rejected from their home/family. The present study analyzed the continuous deprivation of trans people rights from family to community having no secure rights of education, health and professional life conducting interviews from a group of trans residing in segregated areas of Multan, Pakistan. The findings also revealed the consequences of banishment, throws their life away from mainstream of a life a normal human being must have. The data in this paper has been collected by using qualitative research technique with participant observation and in-depth interviews.
KAJIAN PELAKSANAAN E-TILANG UNTUK ANGKUTAN BARANG
Authors: Haradongan Fedrickson 
Published: September 2021

Penerapan E-Tilang bagi angkutan barang telah mulai diberlakukan dari awal maret tahun 2018. Sistem e-tilang di jembatan timbang memungkinkan proses tilang bisa berjalan dengan lebih cepat, sehingga kedua belah belah pihak (petugas dan pelanggar lalu lintas) tidak perlu membuang banyak waktu untuk proses persidangan. Sistem yang menggunakan aplikasi elektronik ini juga akan memudahkan proses kelanjutan dari tilang, sehingga pelanggar lebih mudah dalam menyelesaikan perkara tilang yang sedang dijalaninya. Bukan hanya itu saja, bagi petugas, sistem ini juga akan memungkinkan terjadinya transparansi di dalam proses tilang itu sendiri. E-Tilang tentu akan dapat menekan aksi pungli yang sering terjadi pada sistem tilang manual, di mana kemungkinan kesalahan prosedur dan kelalaian oleh oknum petugas bisa saja terjadi. Sistem E-tilang menggantikan sistem tilang manual yang menggunakan menggunakan blanko/surat tilang, dimana pengendara yang melanggar akan dicatat melalui aplikasi yang dimiliki database UPPKB (Unit Pelaksana Penimbangan Kendaraan Bermotor). E-tilang seharusnya memiliki kelebihan pelayanan yang lebih cepat dari pada tilang konvensional. Kelebihannya adalah sistem ini sangat praktis dan cepat. Penerapan sistem tilang elektronik (E-tilang) ini untuk memfasilitasi kecepatan dan kemudahan, keterbukaan pelaksanaan proses tilang atau sebagai pengganti proses tilang di tempat. Penerapan E-tilang angkutan barang sebenarnya sebuah pilihan penindakan yang efektif kepada pelanggaran over dimensi dan over load angkutan barang. Walaupun demikian belum dapat dikatakan bahwa pelaksanaan E-tilang angkutan barang ini efektif karena proses digitalisasi E-tilang angkutan barang di Indonesia masih belum optimal (membutuhkan waktu berhari-hari).