bluuebunny/crossref_metadata_2025_split huggingface dataset:
Protecting High-Risk Oncology Patients During the COVID-19 Pandemic by Creating an Isolated Outpatient Clinic
Authors: Abedi Seyed Mohammad , Lekkala Manidhar , Moftakhar Bahar , Clarke Tammy , Patel Arpan 
Published: December 2021

PURPOSE: Delivering care for immunocompromised, high-risk patients with cancer during a pandemic has proven challenging. Patients with cancer on chemotherapy have a high risk of mortality if contracted COVID-19. If a patient goes directly to the emergency room, multiple contact points with other individuals can lead to unnecessary exposures from any airborne virus, such as COVID-19. Our cancer center has implemented an isolated clinic with personal protective equipment and direct access to a COVID-19 rule-out floor to manage those with febrile neutropenia (FN). METHODS: We implemented an outpatient, isolated, extended-hour clinic with access to personal protective equipment, laboratories, and antibiotics for patients with FN as a pilot project from April 1 to December 31, 2020, with the aim to decrease emergency department (ED) visits for FN by 50%. RESULTS: Since the implementation of our clinic, we have screened 74 unique patients during 102 visits, of which 76 led to a discharge and 26 led to a direct admit, thus avoiding the ED. Thirty-nine of these visits were for patients with recent travel or a known COVID-19 exposure. Bringing these patients to our isolated clinic ensured safety of the approximately 200 patients undergoing active treatment in our infusion center daily. CONCLUSION: Implementing this clinic has thus far successfully decreased the social footprint of our highest-risk patients with cancer in the ED considerably. Our efforts and hopes of decreasing the possible exposure of our immunocompromised patients to COVID-19 as well as the unnecessary exposure of the infusion center patients and personnel have thus far been effective.
Quantum cosmology with vector torsion
Authors: Kasem A. , Khalil S. 
Published: December 2021

Abstract
We extend the treatment of quantum cosmology to a manifold with torsion. We adopt a model of Einstein-Cartan-Sciama-Kibble compatible with the cosmological principle. The universe wave function is shown to be subject to a

. With a vanishing energy-momentum tensor, the universe evolution in the semiclassical and classical regimes is shown to suggest a two-stage inflationary process induced by torsion.
Effect of

-ray irradiation on performance of LiNbO3-based piezoelectric vibration sensors
Authors: Wei Huifen , Geng Wenping , Bi Kaixi , Li Tao , Li Xiangmeng , Zhang Huiyi , Li Yudong , Xun Mingzhu , Chou Xiujian 
Published: December 2021

Abstract
LiNbO3 (LN)-based micro-electro-mechanical systems (MEMS) vibration sensors exhibit giant perspectives in extreme environments, where a great amount of irradiation exists. However, to the best of our knowledge, it is still unknown whether the irradiation affects the performance of LN-based piezoelectric MEMS sensors. Based on this consideration, it is necessary to model the irradiation environment to investigate the effect of high-dosage irradiation on LN-based vibration sensors. Firstly, the theoretical work is done to study the Compton effect on the gamma-ray irradiation with a 60Co source. After irradiation, X-ray diffraction (XRD) characterization is performed to verify the effect of irradiation on the crystalline of LN thin film. Meanwhile, the performances of output voltages on the five MEMS devices under various dosage of irradiation are compared. As a result, a neglected shift of 0.02 degrees is observed from the XRD image only under maximum irradiation dosage of 100 Mrad(Si). Moreover, the output voltages of cantilever beam vibration sensors decrease by 3.1%. Therefore, it is verified that the γ-ray irradiation has very little influence on the LN-based MEMS vibration sensors, which have great attraction on the materials and sensors under high-dose irradiation.
Psychosis
Authors: Julayanont Parunyou , Suryadevara Uma 
Published: December 2021

ABSTRACT

PURPOSE OF REVIEW
Psychosis can manifest in primary psychotic disorders, neurologic diseases, and medical conditions. This article reviews the definition of psychotic symptoms and the evaluation and management of psychosis in primary psychiatric and neurologic disorders frequently seen in neurologic practice.

RECENT FINDINGS
Emerging evidence supports significant connections between psychosis and structural and functional brain changes in both primary psychotic and neurologic disorders. In addition to antidopaminergic activity, the mechanism of new-generation antipsychotics shifts to act on serotonin receptors, which potentially contributes to their benefits in the treatment of negative symptoms of psychosis and a lesser frequency of extrapyramidal side effects compared with typical antipsychotics. This is also helpful in the treatment of psychosis in patients who have neurodegenerative diseases and are vulnerable to developing extrapyramidal side effects from typical antipsychotics.

SUMMARY
Even with significant overlap, management of psychosis in primary psychotic disorders differs from the approach of psychosis in neurologic diseases. This article helps clinicians learn how to practically evaluate psychosis from both psychiatric and neurologic perspectives.
Posttraumatic Stress Disorder and Anxiety-Related Conditions
Authors: Williamson John B. , Jaffee Michael S. , Jorge Ricardo E. 
Published: December 2021

ABSTRACT

PURPOSE OF REVIEW
This article provides a synopsis of current assessment and treatment considerations for posttraumatic stress disorder (PTSD) and related anxiety disorder characteristics. Epidemiologic and neurobiological data are reviewed as well as common associated symptoms, including sleep disruption, and treatment approaches to these conditions.

RECENT FINDINGS
PTSD is no longer considered an anxiety-related disorder in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition classification and instead is associated with trauma/stressor-related disorders. PTSD symptoms are clustered into four domains including intrusive experiences, avoidance, mood, and arousal symptoms. Despite this reclassification, similarities exist in consideration of diagnosis, treatment, and comorbidities with anxiety disorders. PTSD and anxiety-related disorders are heterogeneous, which is reflected by the neural circuits involved in the genesis of symptoms that may vary across symptom domains. Treatment is likely to benefit from consideration of this heterogeneity.
Research in animal models of fear and anxiety, as well as in humans, suggests that patients with PTSD and generalized anxiety disorder have difficulty accurately determining safety from danger and struggle to suppress fear in the presence of safety cues.
Empirically supported psychotherapies commonly involved exposure (fear extinction learning) and are recommended for PTSD. Cognitive-behavioral therapy has been shown to be effective in other anxiety-related disorders. Selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs) are commonly used in the treatment of PTSD and anxiety disorders in which pharmacologic intervention is supported. Treating sleep disruption including sleep apnea (continuous positive airway pressure [CPAP]), nightmares, and insomnia (preferably via psychotherapy) may improve symptoms of PTSD, as well as improve mood in anxiety disorders.

SUMMARY
PTSD has a lifetime prevalence that is close to 10% and shares neurobiological features with anxiety disorders. Anxiety disorders are the most common class of mental conditions and are highly comorbid with other disorders; treatment considerations typically include cognitive-behavioral therapy and pharmacologic intervention. Developing technologies show some promise as treatment alternatives in the future.
Behavioral and Cognitive Aspects of Concussion
Authors: Bauer Russell M. , Jaffee Michael S. 
Published: December 2021

ABSTRACT

PURPOSE OF REVIEW
This review provides the reader with an overview of concussion and mild traumatic brain injury (TBI). Key aspects of the pathophysiology, signs, and symptoms, treatment and rehabilitation, and recovery from concussion/mild TBI are reviewed with an emphasis on the variety of factors that may contribute to cognitive concerns following injury.

RECENT FINDINGS
Concussion remains a clinical diagnosis based on symptoms that occur in the immediate aftermath of an applied force and in the hours, days, and weeks thereafter. Although advances have been made in advanced diagnostics, including neuroimaging and fluid biomarkers in hopes of developing objective indicators of injury, such markers currently lack sufficient specificity to be used in clinical diagnostics. The symptoms of concussion are heterogeneous and may be seen to form subtypes, each of which suggests a targeted rehabilitation by the interdisciplinary team. Although the majority of patients with concussion recover within the first 30 to 90 days after injury, some have persistent disabling symptoms. The concept of postconcussion syndrome, implying a chronic syndrome of injury-specific symptoms, is replaced by a broader concept of persistent symptoms after concussion. This concept emphasizes the fact that most persistent symptoms have their basis in complex somatic, cognitive, psychiatric, and psychosocial factors related to risk and resilience. This framework leads to the important conclusion that concussion is a treatable injury from which nearly all patients can be expected to recover.

SUMMARY
Concussion/mild TBI is a significant public health problem in civilian, military, and organized athletic settings. Recent advances have led to a better understanding of underlying pathophysiology and symptom presentation and efficacious treatment and rehabilitation of the resulting symptoms. An interdisciplinary team is well-positioned to provide problem-oriented, integrated care to facilitate recovery and to advance the evidence base supporting effective practice in diagnosis, treatment, and prevention.
Language and Aphasias
Authors: Nadeau Stephen E. 
Published: December 2021

ABSTRACT

PURPOSE OF REVIEW
This article reveals how it is possible for a brain composed of 100 billion highly interconnected, lipid-encased, reticular electrochemical devices to support complex functions such as language and how language disorders can be understood as a reflection of degradation of one or more domains of knowledge.

RECENT FINDINGS
Ongoing research, building on landmark work regarding parallel distributed processing (PDP), provides the basis for understanding cognitive functions as a manifestation of the activity of populations of millions or billions of neurons in various highly interconnected networks. Population encoding networks have the following intrinsic properties that provide an orderly explanation for normal and degraded language: (1) a capacity for settling into stable “attractor” states; (2) processing occurs in and knowledge (long-term memories) is stored in exactly the same network; (3) a capacity for incorporating statistical regularities of experience, frequency, and age of acquisition; (4) support of content-addressable memory; and (5) graceful degradation, such that lesions increase the probability of errors but do not fundamentally transform network operations. Knowledge in parallel distributed processing networks resides in the strength of connections between units (synapses in the brain). Aphasia, whether stemming from stroke or dementing disorders, can be understood in terms of the degradation of one or more domains of knowledge.

SUMMARY
Understanding the brain as a population encoding machine incorporating vast interconnectivity provides an orderly explanation for language function, both normal and abnormal.
Spatial Neglect and Anosognosia After Right Brain Stroke
Authors: Barrett A. M. 
Published: December 2021

ABSTRACT

PURPOSE OF REVIEW
Up to 80% of survivors of right brain stroke leave acute care without being diagnosed with a major invisible disability. Studies indicate that a generic cognitive neurologic evaluation does not reliably detect spatial neglect, nor does it identify unawareness of deficit after right brain stroke; this article reviews the symptoms, clinical presentation, and management of these two cognitive disorders occurring after right brain stroke.

RECENT FINDINGS
Stroke and occupational therapy practice guidelines stress a quality standard for spatial neglect assessment and treatment to reduce adverse outcomes for patients, their families, and society. Neurologists may attribute poor outcomes associated with spatial neglect to stroke severity. However, people with spatial neglect are half as likely to return to home and community, have one-third the community mobility, and require 3 times as much caregiver supervision compared with similar stroke survivors. Multiple randomized trials support a feasible first-line rehabilitation approach for spatial neglect: prism adaptation therapy; more than 20 studies reported that this treatment improves daily life independence. Evidence-based treatment of anosognosia is not as developed; however, treatment for this problem is also available.

SUMMARY
This article guides neurologists’ assessment of right brain cognitive disorders and describes how to efficiently assemble and direct a treatment team to address spatial neglect and unawareness of deficit.
Twilight and Me: A Soliloquy
Authors: Drubach Daniel Alejandro 
Published: December 2021

ABSTRACT
Dementia with Lewy bodies (DLB) is the third most frequent type of dementia. The range of symptoms it causes is quite broad and includes parkinsonism, autonomic dysfunction, cognitive deficits, visual and auditory hallucinations, dream disturbances, and other unusual manifestations such as “sense of presence,” Capgras syndrome, and fluctuations in neurologic status. The author, an experienced behavioral neurologist and previous Continuum author, has been diagnosed with DLB and assumes the dual role of physician and patient. Each role provides a unique perspective. He discusses the importance of hope and fear in coping with the illness.
κ-Carrageenan Gel Modified Mesoporous Gold Chronocoulometric Sensor for Ultrasensitive Detection of MicroRNA
Authors: Salahuddin Bidita , Masud Mostafa Kamal , Aziz Shazed , Liu Chia-Hung , Amiralian Nasim , Ashok Aditya , Hossain S M Azad , Park Hyeongyu , Wahab Md Abdul , Amin Mohammed A , Chari M Adharvana , Rowan Alan E , Yamauchi Yusuke , Hossain Md Shahriar A , Kaneti Yusuf Valentino 
Published: December 2021

Abstract
Hydrogel-functionalized surface-based transducers demonstrate fluid-like kinetics, non-fouling properties, and superior biocompatibility. The integration of such properties of three-dimensional (3D) micro- or macrostructure of hydrogels into a mesoporous platform provides a favorable moiety for incorporating biomolecule for adsorption or hybridization with a capture agent. Herein, we report a novel κ-carrageenan hydrogel-coated mesoporous gold (Au) electrode (abbreviated as MPGE/gel) for chronocoulometric (CC) detection of microRNA (miRNA). The κ-carrageenan gel provides a 3D porous network on Au electrode surface to enable higher adsorption of target miRNA for CC interrogation of miRNA in presence of a redox molecule-ruthenium hexaammine (III) chloride ([Ru(NH3)6]3+, RuHex). Magnetically isolated and purified target miR-9-2 is adsorbed onto the MPGE via Au-RNA affinity interaction through the porous 3D network of the gel followed by the CC detection. The enhanced miRNA adsorption and electrocatalytic activity of MPGE/gel provide attomolar (50 aM) level of detection of miRNA with a dynamic range from 100 pM to 10 aM. The good reproducibility (% RSD ≤ 5%, for n = 3) and high specificity of the developed biosensor demonstrates its excellent translational potential toward developing precisely controlled sensing devices for current clinical needs.
Autism Spectrum Disorder and screen time during lockdown: an Italian study.
Authors: Logrieco Maria Grazia , Casula Laura , Ciuffreda Giuseppe Niccolò , Nicolì Ilaria , Spinelli Maria , Di Domenico Alberto , Lionetti Francesca , Novello Roberta , Valeri Giovanni , Fasolo Mirco , Vicari Stefano 
Published: December 2021

Background: Lockdown due to Covid-19 pandemic brought deep changes to the daily lives of children with Autism Spectrum Disorder (ASD), greatly increasing their amount of time spent at home. Methods: A cohort of 243 parents of children with ASD (2-15 years old) completed an original online survey regarding the child’s screen time and the modification of the ASD symptomatology during lockdown to investigate the relationship between them. Results: The data show that high solitary screen time is related with the worsening of ASD core symptoms. Conclusions: This study may help to increase awareness in the excessive use of screen in children with ASD during the lockdown, both during the pandemic as well as after it ends.
Predictive modelling of arsenate (As(V)) adsorption onto surface-engineered magnetite nanoparticles
Authors: Devaraj Nisha Kumari , Hamzah Ameer Al Mubarak 
Published: December 2021

Background: Since adsorption is a complex process, numerous models and theories have been devised to gain general understanding of its underlying mechanisms. The interaction between the adsorbates and adsorbents can be identified via modelling of the adsorption data with different adsorption isotherms as well as kinetic models. Many studies are also focused on developing predictive modelling techniques to facilitate accurate prediction of future adsorption trends. Methods: In this study, a predictive model was developed based on a multiple linear regression technique using existing data of As(V) adsorption onto several coated and uncoated magnetite samples. To understand the mechanisms and interactions involved, the data was first modelled using either Temkin or Freundlich linear isotherms. The predicted value is a single data point extension from the training data set. Subsequently, the predicted outcome and the experimental values were compared using multiple error functions to assess the predictive model’s performance. Results: In addition, certain values were compared to that obtained from the literature, and the results were found to have low error margins. Conclusion: To further gauge the effectiveness of the proposed model in accurately predicting future adsorption trends, it should be further tested on different adsorbent and adsorbate combinations.
Return on investment (ROI) in subscription databases by Nigerian academic libraries: a survey
Authors: Oyadeyi Adekunle Emmanuel , Oladokun Taofeek Abiodun , Shorunke Oludare Adebanji , Fasola Omobolanle Seri 
Published: December 2021

Aim: There seems to be a dearth of literature on how much Nigerian university libraries are spending on the acquisition of Online Electronic Database (OED). This study sets out to investigate the annual cost of acquiring this important and evolving aspect of library collection with the view of determining whether the returns in terms of utilization is commensurate with the invested fund.
Methodology: The study adopts a quantitative research method. A self-developed questionnaire was used to collect data from 55 librarians in 41 academic libraries across Nigeria. The data collected were processed using Statistical Package for the Social Sciences (SPSS) version 20.
Findings: Academic libraries in Nigeria spend an average of ₦12,500,000 or $32,637 on OED subscriptions annually. The study has shown that Nigerian academic libraries usually subscribe to the EBSCOhost and Research4Life databases with few adding specialized databases such as Law Pavilion, HeinOnline, Legalpedia, and ScienceDirect. To ensure adequate returns on investment, the libraries are massively providing support infrastructures, user education, and other information services. However, challenges limiting the widespread use of online databases include irregular power supply and slow internet connectivity among others.
Conclusions: The study, therefore, concludes that there is a middling to low return on subscribed OED in Nigerian academic libraries. However, there are still various huddles that must be scaled for Nigerian academic libraries to reap adequate returns on their investments in online electronic databases.
Survey of users’ level of satisfaction toward inclusive management and marketing of library service in Nigeria
Authors: Obinyan Oluwatoyin 
Published: December 2021

Aim: Information and Communication Technologies (ICTs) brought significant innovation and improvement to library services and methods of meeting user needs. Assessment of user satisfaction with the various library services is an important variable toward inclusive library management and marketing of library services in the 21st century. With the application of ICTs bringing about different resources and various accessibility modes (print and online), it became necessary to investigate user satisfaction with various available library resources and services.
Methods: The study addressed user satisfaction using adapted customer satisfaction scores (CSAT) metric with Rodski Survey to elicit information from 560 respondents that visited the library within the space of one week. The questionnaire was given to the respondents during their library visit twice daily for one week and the process excluded those that have filled the questionnaire before.
Results: The data collected were analysed using descriptive statistics. The findings revealed the level of user satisfaction to be average. It was also discovered that the resources in the library did not meet their information needs as the majority responded that the resources are inadequate and the overall assessment of their interaction with librarians is excellent despite the inadequate resources.
Conclusion: Based on the findings, recommendations were made to create a holistic marketing strategy to improve usability of the library, to acquire more resources and funding to meet user expectations, and to address the need for adequate management of library resources.
Duchowni prawnie uznanych wyznań jako świadkowie w postępowaniu podatkowym
Authors: Nowak Ireneusz 
Published: December 2021

Przedmiotem artykułu są zagadnienia związane z wykorzystaniem przez organy administracji publicznej w jurysdykcyjnym postępowaniu podatkowym środka dowodowego z przesłuchania osoby duchownej jako świadka. Autor podkreśla, że zgodnie z art. 195 pkt 3 Ordynacji podatkowej świadkami nie mogą być duchowni prawnie uznanych wyznań co do faktów objętych tajemnicą spowiedzi, jednakże już inne wiadomości pozyskane przez duchownego – w ramach szeroko rozumianej „opieki duchowej” – nie mieszczą się w powyższym bezwzględnym zakazie dowodowym. Stąd też autor zgłasza postulat de lege ferenda, aby wprowadzić do art. 195 pkt 3 o.p., wzorem m.in. Ordynacji podatkowej z 1934 r., tzw. tajemnicę duchowną/duszpasterską, która dotyczyłaby wszystkich wiadomości/informacji uzyskanych przez osoby duchowne prawnie uznanych wyznań przy wykonywaniu swoich „funkcji duszpasterskich”, a nie stricte związanych z instytucją spowiedzi.