bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Thr715Pro P-Selectin Gene Polymorphism in Diabetic Retinopathy in North Indian Population: A Prospective Clinical Study
Authors: Sharma Ritika , Kant Shri , Mishra Deepak , Srivastav Tanmay , Singh Hemendra 
Published: November 2021

Introduction: The aim of this study was to evaluate the role of Thr715Pro P-Selectin gene polymorphism in patients with Diabetic Retinopathy in North Indian population and establish its role in the pathophysiology as an independent factor.
Materials and methods: This is a prospective clinical study conducted on 60 patients at a tertiary care centre in North India over a period of eighteen months. Sixty patients satisfying the inclusion criteria were selected from the Vitreoretina clinic in the department. They were categorised equally in three groups namely Diabetics with diabetic retinopathy (DwDR), Diabetics without diabetic retinopathy (DwoDR), and non diabetics. The non-diabetics group was further divided into healthy controls, Hypertensive Retinopathy (HR) and Non-exudative Age Related Macular Degeneration (NEAMD). All the patients underwent complete ophthalmic evaluation and blood samples were drawn for the genetic study with their informed consent. Data was analysed using SPSS software version 16.
Results: The genotypic analysis between DwDR, DwoDR and the three subgroup of controls comprising of healthy controls, HR and NEAMD showed that Thr715Pro (A/C) polymorphism prevalence was significantly high in DwDR (p = 0.003) and DwoDR (p = 0.003) compared to healthy controls. No significant difference was noted between DwDR, DwoDR and the HR and NEAMD groups.
Conclusion: Thr715Pro P-Selectin gene Polymorphism could not be established as an independent factor in the pathogenesis of diabetic retinopathy, as its association is found with other systemic diseases which create a prothrombotic state.
Arrugas Bone Trephine Assisted Flapless Dacryocystorhinostomy with Circumosteal – Mitomycin C Versus External Dacryocystorhinostomy: A Hospital Based Comparative Study
Authors: Bhaskar Gyan , Ambastha Anita , Mohan Nilesh , Sinha Shalini , Shree Srishti 
Published: November 2021

Introduction: Primary acquired nasolacrimal duct obstruction is a common ophthalmic condition and has conventionally been managed by external dacryocystorhinostomy. However this procedure is time consuming and involves making mucosal flaps. The aim of this study was to compare the surgical outcome in Arrugas bone trephine-assisted flapless dacryocystorhinostomy with Circumosteal - Mitomycin C versus conventional external dacryocystorhinostomy.
Materials and methods: This is a retrospective non-randomized study of surgical outcome in patients of primary acquired nasolacrimal duct obstruction who underwent an Arrugas bone trephine assisted flapless dacryocystorhinostomy with Circumosteal - Mitomycin C (group A) versus those who underwent conventional external dacryocystorhinostomy (group B) in a teaching hospital in North India. Patients with previously failed dacryocystorhinostomy, lacrimal fistula, canalicular and common canalicular obstruction were excluded. Success was defined as patent syringing at the end of one year. Surgical time was calculated from skin incision to skin suturing.
Results: There was complete resolution of epiphora with patent syringing in 43 out of 52 patients in group A, while in group B, 47 out of 55 patients had complete resolution of epiphora with patent syringing at the end of one year (p= 0.77). Mean surgical time was significantly lower in Group A than in Group B (p=<.05). Scarring and closure of the ostium was the most common cause of failure in both groups (Group A, n=5, 9.6%; Group B, n= 3, 5.45%).
Conclusion: Arrugas bone trephine-assisted flapless dacryocystorhinostomy with Circumosteal - Mitomycin C is a viable alternative to conventional external dacryocystorhinostomy with comparable success rate and shorter surgical time and a faster learning curve.
Female Clients Satisfaction towards Primary and Secondary Eye Health Facilities and Cost of Eye Care in Nepal
Authors: Upreti Oli Radhika , Poudel Manish , Hazel Yadira Perez , Manandhar Anu , Shrestha Mohan Krishna , Gurung Reeta 
Published: November 2021

Introduction: In Nepal, females suffer from disproportionately higher burden of blindness and vision impairment with low access to eye care. The available knowledge is inadequate to address the issues related to gender and generate information to reduce the gender disparity. The aim of this study was to determine female clients’ satisfaction with services at eye facilities in Nepal and to estimate the cost of cataract surgery.
Materials and methods: Exit interviews were conducted in 2018 with 308 female clients from eight facilities in five districts. Face to face interviews were conducted using a pretested semi-structured questionnaire adopted from the midterm review of Vision 2020.
Results: The mean age of participants was 54±17 years. Ninety seven percent (97%) of the participants reported that they received service as per their expectation and were satisfied with the service of the facilities. Major factors for satisfaction were: thorough eye examination (54%), behavior of health staff (40%), and cleanliness of health facility (39%). Another eighty percent (80%) of the participants mentioned that they would recommend or return to the same facility. Fifteen percent of the participants perceived that they faced problems at the eye facility because of their gender. Around three quarters (73%) paid health expenses from their pocket. Most (83%) of the participants rated user fees as either reasonable or inexpensive.
Conclusion: The majority of participants reported receiving service as expected and willingness to return to the same eye health facility for future consultation. However, most participants had to pay the health care expenses out-of-pocket.
Tuberculosis related Neuroretinitis and Retinal Vasculitis in an Immunocompetent Patient
Authors: Goel Neha 
Published: November 2021

Introduction: This study aimed to describe the occurrence of bilateral neuroretinitis and retinal vasculitis in an immunocompetent female with disseminated tuberculosis.
Case description: A 25 year old female diagnosed with disseminated tuberculosis presented with sudden painful loss of vision bilaterally. On examination she was found to have bilateral neuroretinitis and retinal periphlebitis involving the posterior pole. She was prescribed systemic steroids in addition to the anti-tuberculous therapy that she was receiving. The fundus lesions gradually resolved over four months with modest improvement in visual acuity. There were no recurrences in the follow up period of 14 months.
Conclusions: Ocular involvement in the form of neuroretinitis with concomitant retinal vasculitis can occur in patients with disseminated tuberculosis. Addition of systemic steroids to anti-tuberculous therapy leads to anatomical resolution with improvement in visual acuity.
Et tu Mucor?
Authors: Khatri Anadi , Prasai Gunjan , Pandey Mukesh , Kharel Muna , Bohara Dikshya , Panthi Madhav , Thapa Najara , Jha Bhaskar , Pradhan Eli 
Published: November 2021

Introduction: Recently, the Indian subcontinent has been hard hit by the second wave of COVID-19. Along with it, the region has become a hot spot for mucormycosis infection in patients with COVID-19. The aim of this paper is to provide a scientific overview on the status of mucormycosis in pre-COVID-19 era and on how COVID-19 could have directly or indirectly expose the hidden burden of mucormycosis globally.
Materials and methods: This paper is structured as a narrative review and is based on relevant published literature on both COVID-19 and mucormycosis.
Conclusion: Mucormycosis in the pre-COVID-19 era was almost a neglected entity. It was because the risk factors for both - More severe COVID-19 infections and Mucormycosis are almost similar – COVID-19 might have helped to expose the true magnitude of the mucormycosis and flagging it as a major public health concern requiring a revisit by medical science.
Sistem Informasi Bukti Serah Terima Kendaraan Berbasis Web Pada PT. Setiajaya Mobilindo Toyota Bogor
Authors: Bakhri Syamsul , Haidir Ali , Firandani Dini Novia 
Published: November 2021

PT. Setiajaya Mobilindo merupakan salah satu dealer resmi Toyota yang menekankan strategi pemasaran dan layanan yang baik untuk memberikan kepuasan secara menyeluruh bagi pelanggan, mulai dari ketersediaan informasi yang memadai mengenai produk, proses penjualan, dan pasca pembelian produk. Divisi CRC (Costumer Relation Coordinator) merupakan divisi pada PT. Setiajaya Mobilindo Toyota Bogor yang bertempat di bagian front office dan berperan penting dalam mengolah data BSTK (Bukti Serah Terima Kendaraan). Permasalahan dalam pengolahan data BSTK yang masih dilakukan secara manual, divisi Administrasi dan divisi Head CRC kesulitan mendapat data tersebut untuk mengkonfirmasi kendaraan yang dikirim dan untuk laporan penjualan perminggu dengan mudah dan cepat tanpa harus menghubungi beberapa divisi diantaranya divisi CRC dan divisi Security. Penelitian ini bertujuan untuk meningkatkan kinerja CRC dengan membangun sistem informasi berbasis web sehingga mampu membuat pekerjaan pengolahan data terasa lebih cepat dan keamanan datanya pun terjaga dengan baik. Metode yang digunakan untuk mengumpulkan data diantaranya observasi, wawancara, studi pustaka dan tools UML untuk pendokumentasian sistemnya. Penelitian ini menghasilkan sebuah aplikasi berbasis web bukti serah terima kendaraan pada PT. Setiajaya Mobilindo Toyota. PT. Setiajaya Mobilindo is one of Toyota's authorized dealers that emphasizes good marketing and service strategies to provide overall satisfaction for customers, starting from the availability of adequate information about products, sales processes, and post-purchase of products. The CRC (Customer Relations Coordinator) division is a division at PT. Setiajaya Mobilindo Toyota Bogor which is located at the front office and plays an important role in processing BSTK (Vehicle Handover Proof) data. Problems in processing BSTK data which is still done manually, the Administration division and the CRC Head division have difficulty getting the data to confirm the vehicles sent and for weekly sales reports easily and quickly without having to contact several divisions including the CRC division and the Security division. This study aims to improve the performance of CRC by building a web-based information system so that it can make data processing work feel faster and data security is well maintained. For the data collection method, the writer uses observation, interviews, literature study and UML tools for documenting the system. This research produces a web-based application of Vehicle Handover Proof at PT. Setiajaya Mobilindo Toyota.
Test-Driven Development pada Pengembangan Aplikasi Android untuk Memantau COVID-19
Authors: Jonathan Federick , Pakereng Magdalena Ariance Ineke 
Published: November 2021

Dalam pengembangan perangkat lunak, terdapat banyak teknik dan pendekatan yang digunakan untuk menghasilkan perangkat lunak yang handal. Kualitas perangkat lunak sangat bergantung pada pengujian perangkat lunak. Namun tidak semua pengembang peduli dengan tahapan pengujian pada sebuah perangkat lunak. Penelitian ini bertujuan untuk mengetahui pengaruh dari menerapkan proses pengujian dalam mengembangkan perangkat lunak dengan menggunakan metode TDD. Pada Metode TDD, pengembangan perangkat lunak dimulai dengan menulis test case terlebih dahulu lalu kemudian menulis kode. Pada artikel ini, dikembangkan aplikasi mobile dengan menerapkan metode TDD. Perangkat lunak yang dikembangkan adalah berupa sistem informasi mengenai data laporan kasus COVID-19. Data diambil dari Johns Hopkins University The Center of Systems Science and Engineering (JHU CSSE). Hasil penerapan metode TDD menunjukkan bahwa fungsi dan fitur dari perangkat lunak yang dibangun dapat bekerja dan terintegrasi dengan baik antar satu sama lain. Kode yang dihasilkan dari penerapan TDD juga menjadi rapih karena dilakukannya proses refactoring. In Software Engineering, there are many techniques and approaches that can be used to build a reliable software. The quality of a software relies mostly on the software testing process. However, not many developers are bothered with the testing step of a software. The purpose of this article is to learn the results from implementing a testing process on software developmenty. In TDD, the development is started by writing test case first and then writing code. This article developed a mobile application by applying TDD in the process. The android application that had been developed is an information system about report cases on COVID-19. The cases are coming from Johns Hopkins University The Center of Systems Science and Engineering (JHU CSSE). The result of using TDD in development proves that all functions and features of the developed application are working and integrated well.
HUBUNGAN ANTARA HARGA DIRI DENGAN PERILAKU IMPULSIVE BUYING PADA REMAJA PENGGEMAR K-POP
Authors: Nafeesa Nafeesa , Novita Eryanti 
Published: November 2021

KPop is currently a trend for some teenagers. Most of these teenage Kpop fans feel that being a fan also has to collect various kinds of goods or what is commonly known as merchandise related to their idols. They assume that buying these items will make them true fans no matter what the price. They are willing to spend up to millions of rupiah to get their idol's original products such as albums, clothes, bags, pants, hats, bracelets and so on. Furthermore, this study will analyze the problem of high idol impulsive buying behavior in the adolescent community and determine the relationship between self-esteem and impulsive buying behavior in adolescents. This study will specifically examine whether there is a relationship between self-esteem and impulsive buying behavior in adolescents. This research will use Coopersmith's theory of self-esteem and Rook and Fisher's theory of impulsive buying, which is then examined in terms of its aspects and characteristics. Keywords : Teens, KPop Fans, Impulsive Buying, Self-Esteem
Analisis Pengaruh Harga dan Promosi Terhadap Tingkat Penjualan Pizza Hut di era Covid-19
Authors: Juliana Juliana , Pramezwary Amelda , Catherine Catherine , Dwitama Hermawan , Sentia Indah 
Published: November 2021

Abstract- This study aims to analyze the effect of price and promotion on the sales level of Pizza Hut in the Covid-19 era. This research is a basic research to fill the research gap in sales level studies. two hypotheses and tested using data collected from 150 respondents of pizza hut customers. This research is driven by the Covid-19 pandemic which has brought a downturn for companies in marketing products produced by these companies, especially companies in the field of food and beverage. Researchers use quantitative research with multiple linear regression analysis techniques to analyze how much influence the independent variables interact with. dependent variable. Researchers found that the variable that had the most significant influence on Pizza Hut sales in the Covid-19 era was promotion. The decline in Pizza Hut prices did have an effect on the increase in Pizza Hut sales but the effect was not too significant. This is due to the intense price competition to attract consumers' attention in this pandemic. Thus, it is evident that the Pizza Hut promotion strategy by attracting public sympathy can increase sales in the Covid-19 era.Keywords: price, promotion, sales level, covid-19
HUBUNGAN JUMLAH OBJEK WISATA, HOTEL DAN BIRO PERJALANAN DENGAN JUMLAH WISATAWAN KE D.I.Y.
Authors: Yulianto Atun , Mayasari Citra Unik 
Published: November 2021

ABSTRAK Banyaknya jumlah kunjungan wisatawan di Daerah Istimewa Yogyakarta menjadi peluang besar bagi pelaku industry pariwisata untuk mengembangkan bisnisnya. Namun demikian dibutuhkan konsistensi dalam pengembangan pengelolaan yang berkesinambungan untuk dapat bertahan dalam persaingan. Hal ini terkait dengan kreativitas pengelola untuk berinovasi dalam industry wisata agar usaha pariwisatanya diminati masyarakat. Tujuan penelitian ini adalah untuk mengetahui hubungan antara jumlah objek wisata, hotel dan biro perjalanan dengan jumlah kunjungan wisatawan ke tujuan wisata di D.I. Yogyakarta. Metode penelitian yang digunakan dengan pendekatan diskriptif kualitatif yang didukung analisis data kuantitatif. Hasil penelitian menunjukkan adanya hubungan yang signifikan antara jumlah hotel dan biro perjalanan dengan jumlah kunjungan wisatawan. Nilai signifikansi mendekati 0,000 pada tingkat probabilitas 5%. Sementara jumlah objek wisata tidak memiliki hubungan erat dengan jumlah kunjungan, namun jenis objek wisata memiliki potensi hubungan terhadap jumlah kunjungan wisatawan. Kata Kunci: Objek Wisata, Hotel, Biro Perjalanan, Kunjungan Wisatawan ABSTRACT The large number of tourist visits in the Special Region of Yogyakarta is a great opportunity for the tourism industry players to develop their business. However, consistency in the development of sustainable management is needed to survive in the competition. This is related to the creativity of managers to innovate in the tourism industry so that their tourism business is in demand by the community. The purpose of this study was to determine the relationship between the number of tourist objects, hotels and travel agencies with the number of tourist visits to tourist destinations in D.I. Yogyakarta. The research method used is a qualitative descriptive approach supported by quantitative data analysis. The results showed a significant relationship between the number of hotels and travel agencies with the number of tourist visits. The significance value is close to 0.000 at the 5% probability level. While the number of tourist objects does not have a close relationship with the number of visits, the types of attractions have a potential relationship to the number of tourist visits. Keywords: Tourism Object, Hotel, Travel Agency, Tourist Visit
La conceptualización errada del campo eléctrico con cálculo integral en clases virtuales en estudiantes de física aplicada
Authors: Coello Pisco Silvia Magdalena , Flores Herrera Jorge , Hidalgo Crespo José Armando , Gonzalez Cañizalez Y. 
Published: November 2021

En este trabajo se replicó un método basado en el teorema de Vergnaud sobre la conceptualización del campo eléctrico con cálculo integral realizado en una universidad privada de la ciudad de Guayaquil. El objetivo de este estudio es relacionar y conectar la interacción que existe entre el dominio conceptual – epistemológico (Saber comprender) con el hacer del dominio metodológico (Saber hacer) con el propósito de ampliar y profundizar el concepto mediante la experimentación a través de un material instruccional en las clases virtuales (Teoría de Gagné). Nuestro trabajo se fundamenta en la investigación acción con un enfoque explicativo, ya que desde la óptica de la práctica pedagógica pretendemos dar respuesta a los problemas de conceptualización sobre las variables que participan en el campo eléctrico. El diseño del estudio es experimental se trabajó con grupos intactos, uno de control (Gc) y otro experimental (Ge). Los resultados indican que el grupo experimental desarrolló una mejor conceptualización en los contenidos de campo eléctrico con cálculo integral a diferencia del grupo de control que recibió una instrucción tradicional.
A Course Redesign Project
Authors: Robertson William H. 
Published: November 2021

In the summer of 2019, a cooperative team of Biology faculty and a principal investigator worked to develop a solid set of aligned student learning outcomes across the sections of first semester (BIOL 1305) and second semester (BIOL 1306) of introductory Biology. Additionally, the group worked on course objectives alignment within the scope and sequence of the courses, as well as aligned syllabi. A full course redesign was initiated over the summer, where the goal was to align student learning outcomes (SLOs), assessments, and develop a shared set of syllabi for six sections across two courses of introductory biology.
At UTEP, the overall goal was to integrate adaptive courseware technology tools, open education resources (OER) and active learning strategies within a course redesign in our Learning Management System (LMS), Blackboard, for a number of sections in Biology 1305 and Biology 1306 beginning in the spring of 2020. This is challenging, as much of adaptive courseware technology is not as strong in content as the Biology faculty would like for these classes, although it can help to substantially reduce the costs for students. The information that follows defines the case study for integrating adaptive courseware within the course redesign process for a series of high enrollment introductory Biology courses
Design and calculation of heat transfer of the passive cooling modules for low-pressure hydrogen vessels
Authors: Lázár Marián , Duda Filip , Kmeťová Ľubomíra , Jasminská Natália , Hudák Šimon 
Published: November 2021

This paper deals with the issue of improving the temperature management of a metal hydride tank to reduce the energy intensity of cooling. The problem of absorption and adsorption of hydrogen gas in metals, cooling of metal hydride tanks in the process of hydrogen absorption while protecting the current level of development of science and research for this area is analysed. The work also deals with numerical and experimental verification of a prototype metal hydride tank with passive cooling.