bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Woven EndoBridge (WEB) device: feasibility, techniques, and outcomes after FDA approval
Authors: Mouchtouris Nikolaos , Hasan David , Samaniego Edgar A. , Saiegh Fadi Al , Sweid Ahmad , Abbas Rawad , Naamani Kareem El , Tahir Rizwan , Zanaty Mario , Khanna Omaditya , Chalouhi Nohra , Tjoumakaris Stavropoula , Gooch M. Reid , Rosenwasser Robert , Jabbour Pascal 
Published: October 2021

OBJECTIVE
Wide-neck bifurcation cerebral aneurysms have historically required either clip ligation or stent- or balloon-assisted coil embolization. This predicament led to the development of the Woven EndoBridge (WEB) aneurysm embolization system, a self-expanding mesh device that achieves intrasaccular flow disruption and does not require antithrombotic medications. The authors report their operative experience and 6-month follow-up occlusion outcomes with the first 115 aneurysms they treated via WEB embolization.

METHODS
The authors reviewed the first 115 cerebral aneurysms they treated by WEB embolization after FDA approval of the WEB embolization device (from February 2019 to January 2021). Data were collected on patient demographics and clinical presentation, aneurysm characteristics, procedural details, postembolization angiographic contrast stasis, and functional outcomes.

RESULTS
A total of 110 patients and 115 aneurysms were included in our study (34 ruptured and 81 unruptured aneurysms). WEB embolization was successful in 106 (92.2%) aneurysms, with a complication occurring in 6 (5.5%) patients. Contrast clearance was seen in the arterial phase in 14 (12.2%) aneurysms, in the capillary phase in 16 (13.9%), in the venous phase in 63 (54.8%), and no contrast was seen in 13 (11.3%) of the aneurysms studied. Follow-up angiography was performed on 60 (52.6%) of the aneurysms, with complete occlusion in 38 (63.3%), neck remnant in 14 (23.3%), and aneurysmal remnant in 8 (13.3%). Six (5.5%) patients required re-treatment for persistent aneurysmal residual on follow-up angiography.

CONCLUSIONS
The WEB device has been successfully used for the treatment of both unruptured and ruptured wide-neck bifurcation aneurysms by achieving intrasaccular flow diversion. Here, the authors have shared their experience with its unique technical considerations and device size selection, as well as critically reviewed complications and aneurysm occlusion rates.
Usefulness of anterior column release for segmental lordosis restoration in degenerative lumbar kyphosis
Authors: Park Jin-Sung , Lee Chong-Suh , Choi Youn-Taek , Park Se-Jun 
Published: October 2021

OBJECTIVE
Three-column osteotomies (3COs) for surgical correction of lumbar kyphosis show a strong correction capacity, but this procedure carries high morbidity rates. The anterior column release (ACR) technique was developed as a less invasive procedure. In this study the authors aimed to evaluate sagittal alignment restoration using ACR and to determine factors that affect the degree of correction.

METHODS
This study included 36 patients (68 cases) who underwent ACR of more than one level for adult spinal deformity. Parameters for regional sagittal alignment included segmental lordosis (SL). The parameters for global sagittal alignment included pelvic incidence, lumbar lordosis, sacral slope, pelvic tilt, and sagittal vertical axis (SVA). In addition, the interdiscal height (IDH) and difference of interdiscal angle (DIDA) were measured to evaluate the stiffness of the vertebra segment. The changes in SL were evaluated after ACR and the change of global sagittal alignment was also determined. Factors such as the location of the ACR level, IDH, DIDA, cage height, and additional posterior column osteotomy (PCO) were analyzed for correlation with the degree of SL correction.

RESULTS
Thirty-six patients were included in this study. A total of 68 levels were operated with the ACR (8 levels at L2–3, 27 levels at L3–4, and 33 levels at L4–5). ACR was performed for 1 level in 10 patients, 2 levels in 20, and 3 levels in 6 patients (mean 1.9 ± 0.7 levels per patient). Mean follow-up duration was 27.1 ± 4.2 months. The mean SL of the total segment was 0.4° ± 7.2° preoperatively and increased by 15.3° ± 5.5° at the last follow-up (p < 0.001); thus, the mean increase of SL was 14.9° ± 8.1° per one ACR. Global sagittal alignment was also improved following SL restoration with SVA from 101.9 mm to 31.4 mm. The degree of SL correction was correlated with the location of ACR level (p = 0.041) and was not correlated with IDH, DIDA, cage height and additional PCO.

CONCLUSIONS
This study demonstrated that the mean correction angle of SL was 14.9 per one ACR. The degree of disc space collapse and stiffness of segment did not affect the degree of correction by ACR.
Burden of pediatric neurosurgical disease in a rural developing country: perspectives from southwest Nigeria
Authors: Oyemolade Toyin A. , Adeleye Amos O. , Olusola Ayodele J. , Ehinola Busayo A. , Aikhomu Ebosetale P. , Iroko Anita A. 
Published: October 2021

OBJECTIVE
The proportion of the global burden of neurosurgical disease represented by pediatric neurosurgical pathology is unknown, especially in lower-middle income countries (LMICs) where there exists no known data-driven literature on the subject. In this study, the authors aimed to quantify the pediatric neurosurgical disease profile in a rural area of a developing country.

METHODS
This was a prospective observational study of all pediatric neurosurgical patients managed at a single center over a 30-month period.

RESULTS
Overall, 226 pediatric patients were included in the study (150 males and 76 females, male/female ratio 2:1), accounting for 20.4% of the total patient population during the study period. The modal age distribution was the 0- to 4-year-old group (32.3%), and head injury was the most common presentation, occurring alone in 157 patients (69.5%). Hydrocephalus alone was seen in 21 patients (9.3%) and in combination with myelomeningocele in 4 patients (1.8%). Brain tumors were found in 6 patients (2.7%), infective lesions in 6 patients (2.7%), and encephaloceles in 2 patients (0.9%). The treatment outcome was good in 170 patients (75.2%). Fourteen patients (6.2%) were referred to more advanced health facilities for specialized care; 29 patients (12.8%) were discharged against medical advice, mostly because of financial constraints; and 8 patients (3.5%) died. Several surgical cases could not be performed because of sundry logistical constraints.

CONCLUSIONS
Pediatric neurosurgical disease accounted for one-fifth of the neurosurgical workload at a tertiary health facility in southwest Nigeria. Trauma was the most common presentation, and optimal in-hospital treatment, including surgery, was hampered by severe logistical constraints in a significant proportion of the cases.
PERJANJIAN PINJAM MEMINJAM FINTECH DIHUBUNGKAN KATA SEPAKAT PARA PIHAK SESUAI KETENTUAN PASAL 1320 KUHPERDATA DAN UNDANG UNDANG ITE
Authors: Wulandani  
Published: October 2021

Abstrak
Di era teknologi saat ini, kredit keuangan elektronik melalui perusahaan Financial Technology yang Peer 2 Peer (P2P) Lending telah menjadi salah satu alternatif peminjaman dana dengan cepat. Walaupun memberi kemudahan, akan tetapi pinjaman daring juga memiliki banyak masalah dan risiko kepada masyarakat atau calon peminjam yang melakukan transaksi pinjaman. Cepatnya laju perkembangan tersebut tidak dibarengi dengan sosialisasi dan pemahaman yang baik sehingga dampaknya baru terasa ketika terjadi banyak masalah pasca transaksi.

Dari penelitian hukum yang telah dilakukan dapat disimpulkan bahwa bentuk kesepakatan yang terjadi antara para pihak yaitu pada saat pemberi pinjaman dan penerima pinjaman sepakat atau menyetujui terhadap syarat maupun ketentuan yang diberikan oleh platform penyelenggara yang diikuti dengan pernyataan kehendak. Pernyataan kehendak tersebut dilakukan dengan cara menekan tombol persetujuan (klik agreement) berupa mengklik centang pada platform. Dalam hal terjadi gagal bayar akibat debitur wanprestasi, debitur tetap mendapat perlindungan atas hak-haknya. Pemberi pinjaman dapat melakukan upaya-upaya untuk memperoleh haknya sebagai kreditor yang diwakilkan oleh penyelenggara dalam urusannya dengan penerima pinjaman. Penyelesaian sengketa dapat melalui non-litigasi maupun litigasi sesuai dengan yang diperjanjikan.

Kata Kunci: Perjanjian Fintech, terjadinya kata sepakat, perlindungan hukum.
The mediating role of job autonomy between performance feedback and work performance: A millennial perspective
Authors: Ulrych Wojciech 
Published: October 2021

BACKGROUND: During such an uncertain time like a pandemic, job autonomy can play a pivotal role. It can build bridges between performance feedback and work performance in the millennial workplace. To do so, a set of management practices must be put in place to meet millennial needs. OBJECTIVE: This paper’s aim is to explore how job autonomy can be used at its best in the context of the millennial generation and the relationship to both performance feedback and work performance. METHODS: A theoretical performance feedback-work performance model mediated by job autonomy has been built based on current literature and empirical research. The research sample consisted of 185 purposefully selected working students from the Faculty of Management at the University of Łódź. RESULTS: Individual autonomy can play a positive mediating role between performance feedback and work performance in the millennial workplace. Job autonomy is a partly mediating construct regarding the model. CONCLUSIONS: Job autonomy is an important tool to improve individual performance through individual-tailored performance feedback. This study shows how a line manager can be a more future-oriented coach and an effective listener rather than just being somebody who constantly monitors their work.
YOUTH HEALTH MANAGEMENT SPHERE
Authors: Kononchuk Antonina I. , Svatenkova Tetyana , Svatenkov Oleksandr V. , Kononchuk Danylo I. 
Published: October 2021

Introduction. Health at 10% depends on the medicine level, 20% - on the environment state, 20% - on heredity and 50% - on lifestyle. The healthy lifestyle is forming by: value awareness, conscious attitude, health support; healthy lifestyle; spirituality development; saving and promotion health life. Ukrainian adolescents` health self-assessment is lower than their peers in Europe: every five teenager consider his health mediocre or bad (27%); every third teenager has smoking experience. One in ten teenagers first smoke a cigarette at 11 or earlier, 7% smoke every day; one in seven among 11-year-old and 76% 17-year-old have alcoholic drinking experience; every nine teenagers (aged from 11 to 13 years) tries cannabis at least once. Among 12 million reported sexually transmitted diseases 3 million occur among adolescents.
Purpose. The purpose of the paper is to study the youth awareness level in the health field; to create a youth health center model.
Methodology. An extensive literary review of relevant articles and youth health research reports for the period 2009-2020, was performed using Medline, PubMed and Google databases, with the following key words: "the Ukrainian youth health state, the number of chronically ill among Ukrainian youth, the bad habits spread in the Ukrainian youth environment, youth for a healthy lifestyle". We used a descriptive cross-sectional survey with open-ended and closed-ended questions about attitude to a healthy lifestyle (n = 688).
Results. Youth consider the health as the most comprehensive definition, which is enshrined in the scientific literature (67,7%). Family remains the most influential social institution for young people today. Unemployment, low medical care level and high HIV/AIDS rates are the most important health concerns.
Conclusions. Influencing the safe behavior formation factors is defined, the young people attitude the healthy lifestyle and the mentioned factors have been described. The model of the Youth Health Support and Conservation Centre is presented
INTELLECTUAL DISABILITIES IN PRESCHOOLERS: MENTAL HEALTH DETERMINANTS DURING THE PRENATAL, NATAL AND POSTNATAL DEVELOPMENT STAGES
Authors: Boriak Oksana. V. , Chobanian Anna , Kolyshkin Oleksandr , Kosenko Yurij , Dehtiarenko Tetiana , Kolyshkina Alla 
Published: October 2021

Introduction. A person’s mental health is a successful performance of a mental function, the result of which is a productive activity, establishing relationships with other people and an ability to adapt to change and cope with adverse life circumstances. Particularly acute is the issue of the potential negative impact of impaired development on the mental health and social functioning of children with mental and physical disabilities.
Purpose. The purpose of the paper was to identify correlations between the mental health indicators of mentally retarded preschoolers and the specifics of the prenatal, natal and postnatal stages of their development.
Methodology. Analysis of special medical, psychological and pedagogical literature; comparison and systematization of research material to determine the mental health indicators of preschoolers of mild and moderate degrees of mental retardation; mathematical methods of statistics.
Results and Discussion. These studies show that the events of the prenatal/natal period have a significant impact on the further life of the child. It is a clear fact that close interaction between the mother and the unborn child is confirmed (the child learns to perceive the world together with the mother). However, for the relatively harmonious mental health and social functioning of a child with mental retardation, the mother’s behavior after the birth of the child is of paramount importance. This study does not reveal the entire specifics of mental health indicators of MRP, because the article presents the results of a study covering senior preschool age. School-age children were left out of consideration.
Conclusions. The obtained results confirm the conditionality of mental retardation by negative factors of prenatal, natal and postnatal stages of development. It is important to correctly diagnose the existing manifestations of mental health disorders exactly at the preschool age, in order to implement appropriate measures for correction and development
Analysis of current approaches to the treatment and quality of life improvement in patients with gastroesophageal reflux disease in case of its combination with the syndrome of undifferentiated connective tissue dysplasia
Authors: Romash Iryna 
Published: October 2021

When the structure of the connective tissue is disturbed, the probability of developing pathology of the internal organs increases. The gastrointestinal tract is one of the systems that is most often involved in the pathological process in the case of such disorders. Due to its mesenchymal origin, the esophagus is one of the first to suffer.
Normalization of mineral metabolism, correction of immunological and bioenergetic status are the main tasks in the treatment of such patients. Therapy with magnesium drugs, vitamins, anabolic drugs, ?-blockers, aldosterone antagonists, and amino acid drugs should also be used for this purpose. Patients in this group should also take drugs that contain vitamin D3
La influencia de la especialización productiva y regional en el comportamiento de las exportaciones colombianas del siglo XIX: Un análisis con la metodología Shift Share
Authors: Barrios-Aguirre Fernando 
Published: October 2021

Una de las aproximaciones que nos permite entender la dinámica económica del Siglo XIX en Colombia es por medio de las Exportaciones de este período. Mediante las cifras podemos observar la dinámica de los principales rubros de producción diferentes al oro, así como su dinamismo y contribución al crecimiento de las exportaciones en el siglo XIX: el oro, el tabaco y la quina, y algunos artesanales (intensivos, también, en recursos naturales y trabajo no calificado), como los sombreros de paja, especialmente durante el período de expansión diversificada de exportaciones, 1850-1882. Los movimientos coyunturales así como la inserción de los países de Latinoamérica al proceso capitalista y a los primeros pasos de la globalización nos permiten incidir en la explicación del dinamismo, estancamiento y auge de algunos productos que fueron potencialmente exportables en el siglo XIX. Mediante el escenario de Cambio y Composición se puede observar resultados como la falta de dinamismo de la Quina y el Tabaco en el primer período o las expectativas del periodo dos con la bonanza cafetera y la Quina y la crisis tabacalera de los años 1870 y 1873 que terminó afectando al sector y generando la cifra de dinamismo más baja del periodo de análisis y preparo al café en su expansión del tercer período. De acuerdo con estos resultados, el periodo nos evidencia el camino de una crisis, que realmente se dio entre 1876 y 1877. Algunos aspectos históricos que nos permiten complementar los resultados por países. En efecto se nota el poco dinamismo con Gran Bretaña y Estados Unidos que sucedió en la primera mitad de los años sesenta, el dinamismo de las exportaciones hacia Alemania debido al impulso del mercado de tabaco y el dinamismo en Francia debido al incremento notable que se obtuvo en este periodo. El período dos muestra la recuperación que obtuvo Gran Bretaña en la bonanza quinera, el decaimiento de Alemania debido a la crisis tabacalera y la importancia que va tomando el mercado estadounidense. Muy seguido, el tercer periodo resalta la pérdida del poder comercial de Alemania, pero también un aspecto excepcional el camino de la crisis de los ochentas que afectaría a todos los socios comerciales, excepto a Los Estados Unidos.Palabras Clave: Exportaciones, Siglo XIX, Productos, Socios comerciales, disparidad histórica.
Relación del consumo de alcohol y trastornos mentales en habitantes de una población rural
Authors: Rivas Acuña Valentina , Rodríguez Hernández Carlos Manuel , Arias Guzmán Maríz Roxana , Carrillo Hernández Laura , Zetina Contreras Esmeralda , González Jorge Rafael 
Published: October 2021

El propósito de la investigación fue determinar la relación del consumo de alcohol y trastornos mentales en una población rural del municipio de Centro, Tabasco, México; mediante diseño correlacional-descriptivo, se aplicaron la Entrevista Neuropsiquiátrica Internacional (MINI) y el AUDIT. La muestra fue de n= 400, con edad promedio de 34.2 años. El consumo de alcohol fue perjudicial (76%), con predominio en mujeres. Los principales trastornos identificados fueron: nsiedad generalizada, 69.5%; trastorno antisocial de la personalidad, 60%; agorafobia, 57.7%; trastorno por estrés postraumático, 54.5%; riesgo de suicidio, 53.2% y fobia social, 50.5%. El consumo de alcohol correlacionó significativamente (p= <.01) con: edad (r= .235); trastorno por estrés postraumático (r= .509); trastorno de ansiedad (r= -.457); fobia social (r= -.332) y riesgo de suicidio (r= -.241). El consumo de alcohol de forma perjudicial indica posible dependencia de alcohol y desarrollo de trastornos de ansiedad, trastornos del estado de ánimo y trastorno antisocial
НАПРЯМКИ ВДОСКОНАЛЕННЯ НОРМАТИВНО-ПРАВОВОГО РЕГУЛЮВАННЯ ОРГАНІЗАЦІЇ ДІЯЛЬНОСТІ ПІДРОЗДІЛІВ ТА ОРГАНІВ НАЦІОНАЛЬНОЇ ПОЛІЦІЇ УКРАЇНИ В ПРОТИДІЇ НЕЗАКОННОМУ ОБІГУ НАРКОТИКІВ
Authors: Стрільців О. М. , Буковський Ю. Д. 
Published: October 2021

У статті здійснено аналіз нормативно-правового регулювання організації діяльності підрозділів та територіальних органів Національної поліції України в протидії незаконному обігу наркотиків. За результатами дослідження встановлено, що на сьогодні поліція керується інструкцією з протидії незаконному обігу наркотиків, яка була ще прийнята у 2004 році. При тому в основу цієї інструкції було закладені положення, які були затверджені наказами МВС України ще у 90-і роки минулого століття. Автори виходять із пропозицією прийняти новий нормативно-правовий акт, який би регламентував діяльність підрозділів та територіальних органів Національної поліції України в протидії незаконному обігу наркотиків. Причому, акцентована увага на тому, що зміст такого акту має обов’язково враховувати положення Стратегії державної політики щодо наркотиків на період до 2020 року, схваленої розпорядженням Кабінету Міністрів України від 28 серпня 2013 р. № 735-р. Авторами пропонується орієнтовний зміст нової інструкції, який повинен містити наступні розділи: 1) порядок створення та діяльності дорадчо-консультаційних органів; 2) організація діяльності та повноваження підрозділів та територіальних органів Національної поліції України щодо зменшення незаконних пропозицій на наркотики; 3) організація діяльності та повноваження підрозділів і територіальних органів Національної поліції України щодо зменшення незаконного попиту на наркотики; 4) організація діяльності та повноваження підрозділів та територіальних органів Національної поліції України щодо зменшення шкоди від немедичного вживання наркотиків; 5) співпраця підрозділів та територіальних органів Національної поліції України з громадськими та неурядовими організаціями в протидії незаконному обігу наркотиків; 6) участь підрозділів та територіальних органів Національної поліції України в реалізації безперервності замісної підтримувальної терапії.
Non-Invasive in Vivo Quantification of Directional Dependent Variation in Mechanical Properties for Human Skin
Authors: Lakhani Piyush , Dwivedi Krashn K. , Parashar Atul , Kumar Navin 
Published: October 2021

Skin is the body’s largest organ, and it shows non-linear and anisotropic behavior under the deformation. This behavior of the skin is due to the waviness and preferred orientation (in a particular direction) of collagen fibers. This preferred orientation of collagen fibers results in natural pre-tension and anisotropy of the skin. The knowledge of natural skin pre-tension and anisotropy is essential during incisions and surgery. The available suction-based devices quantify the anisotropy through the displacement field and cannot measure the stress-strain relation in particular directions. Therefore, in the current study, an in vivo full-field measurement suction apparatus was developed to measure the stress and strain of skin in all planar directions through a single experiment. First, this apparatus was tested on silicone substrates of known properties, and then it was used to test the skin of 12 human forearms. Further, to check the effect of hand stability on the measurements, the obtained results of the skin were compared with the results of a standard test performed in the same skin using a steady setup. The consistency between these two results confirms that the stability of the hand does not influence the measurements of skin properties. Furthermore, using the developed apparatus, the skin’s anisotropy and its relation with the Kraissl’s lines orientation was quantified by measuring the toe and linear moduli at an interval of one degree. The minimum and maximum values of the toe and linear moduli were 0.52 ± 0.09 and 0.59 ± 0.11 MPa, and 3.09 ± 0.47 and 5.52 ± 1.13 MPa, respectively. Also, the direction of maximum moduli was found almost similar to Kraissl’s lines’ orientation. These results confirm the contribution of skin pre-tension on the anisotropy of the skin. The present apparatus mimics the tissue expansion procedure, where observation of the test may be helpful in the selection of size and shape of the expander.