bluuebunny/crossref_metadata_2025_split huggingface dataset:
“The immediate effect of neutral spinal compress on heart rate variability in hypertensive individuals”
Authors: Bansal Poornima , Kannarpady Janardan Sujatha , Shetty Prashanth 
Published: August 2021

Abstract

Objectives
Hypertension (HTN) is considered as chronic medical condition. Because of the increased complications associated with the conventional medicine, the effects of naturopathic modalities were emphasized to prevent and minimize those adverse effects. This study was done to assess the immediate effect of neutral spinal compress on heart rate variability and blood pressure and thereby to substantiate the clinical understanding of its effect in hypertensive individuals.

Methods
Hundred hypertensive individuals were recruited for the study. Subjects were assessed for blood pressure (BP) and Heart Rate Variability (HRV) before and immediately after the intervention of 20 min.

Results
Result shows significant reduction in mean heart rate (HR) (p<0.001), low frequency (LF) (p<0.001), low frequency/high frequency (LF/HF) (p<0.001), systolic blood pressure (SBP) (p<0.001) and diastolic blood pressure (DBP) (p<0.001) and significant increase in mean R-R interval (Mean RR) (p<0.001) and high frequency (HF) (p<0.001) components of Heart Rate Variability after neutral spinal compress intervention.

Conclusions
The results of the study reported that full neutral spinal compress reduces the sympathetic tone and shifts the Sympatho-vagal balance in favor of parasympathetic dominance and hence it can be concluded that neutral spinal compress can be effectively used in the management of hypertension.

Trial registration
Clinical Trial Registry- India (CTRI); CTRI Reg. No- CTRI/2020/01/022639.
FBMC OQAM: novel variant of OFDM
Authors: Tiwari Shiv Om , Paulus Rajeev 
Published: August 2021

AbstractOrthogonal frequency division multiplexing (OFDM) revolutionizes the transmission technologies, including, optical as well as wireless communication. In OFDM the orthogonal nature of carriers makes it very good technique for data transfer. Still the out-of-band (OOB) radiation in OFDM leads to inter symbol interference (ISI) and bit error rate (BER) goes down. Moreover amplitude variations of the subcarriers lead to power variations and peak-to-average power ratio (PAPR) problem. To overcome these issues a novel filter bank multicarrier (FBMC) scheme is proposed, where each carrier is allowed to pass through to a separate filter and orthogonality among subcarriers is relaxed. Thus FBMC has better OOB and PAPR performance. In this work, we also have evaluated the PAPR performance by the simulation results. For the improvement of PAPR nonlinear companding scheme along with clipping is presented. The hybrid technique (clipping + companding) parameters are set in such a way that PAPR is reduced while signal power remains constant. Results are also compared with recent methods and it has been found that the proposed technique preforms better than other chosen techniques.
Performance analysis of a hybrid FSO–FO link with smart decision making system under adverse weather conditions
Authors: Mohapatra Pradyut , Singh Garima , Singh Anjali , Kaur Gurjit 
Published: August 2021

Abstract
Optical wireless communication systems employing free-space optical (FSO) links utilize modulated lasers to transmit information. FSO–fiber optic (FO) link provides an alternative possible way in scenarios where infrastructures employing optical fibers are widely destroyed due to disasters or when difficulties are faced during the installation of FO links. Furthermore, the link is integrated with decision-making ability. To encounter the distortions in the received signal carrier-suppressed return-to-zero modulation format has been used. FSO–FO hybrid link has been compared with simple FSO channel. The terrestrial links depend strongly on weather conditions as optical beams propagate through the atmosphere. Atmospheric attenuation could affect the FSO channel and has been considered to analyze the performance of the designed system.
Finite groups whose intersection power graphs are toroidal and projective-planar
Authors: Li Huani , Ma Xuanlong , Fu Ruiqin 
Published: August 2021

Abstract
The intersection power graph of a finite group

G

G

is the graph whose vertex set is

G

G

, and two distinct vertices

x

x

and

y

y

are adjacent if either one of

x

x

and

y

y

is the identity element of

G

G

, or

⟨

x

⟩

∩

⟨

y

⟩

\langle x\rangle \cap \langle y\rangle

is non-trivial. In this paper, we completely classify all finite groups whose intersection power graphs are toroidal and projective-planar.
Organocatalytic total synthesis of bioactive compounds based on one-pot methodologies
Authors: Pellissier Hélène 
Published: August 2021

Abstract
The combination of one-pot methodologies to asymmetric organocatalysis allow a green and direct access to many types of complex highly functionalized chiral products, including important key intermediates in total syntheses of important bioactive compounds. A series of chiral organocatalysts have already been successfully applied to such syntheses. This report collects major developments in the total synthesis of biologically active products based on the use of enantioselective organocatalytic domino/tandem reactions as key steps. It is divided into two parts dealing successively with reactions based on the use of proline-derived catalysts and other organocatalysts.
Anticancer potential of indole derivatives: an update
Authors: Misra Shashi Kiran , Pathak Devender , Pathak Kamla 
Published: August 2021

Abstract
The heterocyclic indole is one of the most prevalent pharmacophores in nature. It has been a highly privileged scaffold for designing targeted and anticancer therapeutics. Countless fused heterocyclic templates have been developed with diverse physicochemical and biological properties. Due to their versatile ethanobotanical and pharmacological values, indole and its derivatives seek high demand in the chemical and healthcare sectors. Extensive anticancer research has been conducted in this decade to evaluate their efficacy for diverse malignancies. The chapter explores the anticancer activity of natural and synthetic indole derivatives expressed through targeting different biological receptors and enzymes.
125I–Amoxicillin preparation as a guide tracer for inflammation detection
Authors: El Refaye Marwa S. , El-Sharawy Dina M. , Hussien Heba 
Published: August 2021

Abstract
The objective of this study is to label Amoxicillin with radioactive iodine (125I-AC) via direct electrophilic substitution to act as a promising tracer for inflammation imaging. The highest labeling yield of 80% was achieved after studying all the parameters affecting the labeling reaction using Iodogen (IG) as an oxidizing agent. Molecular Modeling Structure was done using MOE program to predict the suitable 125I position. The product structure was established by a cold iodination reaction using Iodine-127. Biological evaluation of (125I-AC) was carried out using groups of inflamed mice with different exogenous agents such as E.Coli and Turpentine oil. The (125I-AC) shows an in vitro stability of about 97% after 24 h.While doing in vivo studies over 4 h, the tracer stability of 99% was observed.
Az aktív sportfogyasztás motivációinak vizsgálata általános sportmotivációt mérő skála kialakításával
Authors: Csóka László , Hegedüs Réka , Törőcsik Mária 
Published: August 2021

A TANULMÁNY CÉLJA
Az aktív sportolás mögött húzódó motivációk feltérképezésének fontos szerepe van a sportfogyasztás minél pontosabb megértésében. Kutatásunk célja egy olyan sportolási motivációkat mérő skála kialakítása volt, amivel átfogóan fel tudjuk mérni a magyar lakosság rendszeresen sportoló hányadának sportolási motivációit. Ez a megközelítés újdonságot jelent más sportmotivációs skálakutatásokhoz képest, mivel nem versenysportolókra, hanem az átlagemberek sportolási motivációira fókuszál.
ALKALMAZOTT MÓDSZERTAN
Kutatásunk során saját skálát fejlesztettünk, amit az EFOP-3.6.2-16-2017-00003: „Sport- Rekreációs- és Egészséggazdasági Kooperációs Kutatóhálózat létrehozása” című projekt keretében végzett magyar lakossági sportfogyasztási felméréseken teszteltük. Alapjául egy 2000 fős mintán végezett személyes megkérdezés szolgált, ami reprezentatívnak tekinthető a 15-74 éves magyar lakosságra nem, korcsoportok (10 éves intervallumok) és a lakóhely régiója alapján. A keletkező adatokon a skála mérési dimenzióinak kialakításához faktorelemzést alkalmaztunk, majd meggyőződtünk a keletkező faktorok megfelelő belső megbízhatóságáról. Utolsó lépésben a mintánkon klaszterelemzést végeztünk, hogy meggyőződhessünk skálánk gyakorlati használhatóságáról a magyar lakosság sportmotivációs mintázatainak megállapításához.
LEGFONTOSABB EREDMÉNYEK
Skálánk alkalmasnak bizonyult a hétköznapi emberek sportolása mögötti motivációk mérésére három különböző dimenzió mentén is. Segítségével a magyar lakosság körében sikerült feltárnunk hat különböző sportolási motivációkkal rendelkező csoportot, akik a relaxálók, az elkötelezett testedzők, a közösségi sportolók, az átlagos sportfogyasztók, az önmaguknak megfelelni akarók és a magányos testformálók. Skálánk gyakorlati alkalmazhatóságát bizonyítja, hogy az elkülönített csoportok sportfogyasztása több szempont szerint is jelentős eltéréseket mutat.
GYAKORLATI JAVASLATOK
A kutatásunk során kifejlesztett sportmotivációs skála segítségével a sporthoz kapcsolódó vállalatok pontosabban tudnak szegmentálni és célcsoportokat meghatározni, ami megteremtheti a jobb pozícionálás lehetőségét is. A számos szereplő és a kiélezett verseny miatt ez kulcskérdést jelenhet adott sportvállalat sikeressége szempontjából. Alkalmas azonban a társadalmi célú üzenetek célzott eljuttatásának segítésére is.

Köszönetnyilvánítás: A kutatás az Emberi Erőforrás Fejlesztési Operatív Program, EFOP-3.6.2-16-2017-00003: „Sport- Rekreációs- és Egészséggazdasági Kooperációs Kutatóhálózat létrehozása” című projektjének támogatásával készült.
Are esports bettors a new generation of harmed gamblers? A comparison with sports bettors on gambling involvement, problems, and harm
Authors: Greer Nancy , Rockloff Matthew J , Russell Alex M T , Lole Lisa 
Published: August 2021

AbstractBackground and aimsEsports betting is expanding in popularity, yet little is known about who participates in this niche gambling activity. This study aimed to determine whether esports bettors are more vulnerable to harms and problems than gamblers engaged in traditional sports betting.MethodsData were collected from 298 regular esports bettors and 300 sports bettors (who regularly bet on traditional sports, but not esports). These groups were compared on demographics, gambling involvement, problem gambling, and gambling-related harms.ResultsCompared to sports bettors, esports bettors were more likely to be younger, university-educated, employed (lower income earners), and speak a non-English language at home. Esports bettors gambled on fewer traditional gambling activities in the last 12 months, but compared to sports bettors, gambled more frequently on some activities, were more likely to meet problem gambler criteria (64.8.% vs 17.3%), and experience at least one gambling-related harm (81.9% vs 45.3%). Being an esports bettor significantly predicted greater problem gambling severity and gambling-related harms. More frequent esports skin betting and skin gambling (on games of chance) were significant predictors of gambling problems amongst esports bettors.Discussion and conclusionThe results provide preliminary evidence that esports bettors are more likely to experience gambling problems compared to their sports betting counterparts, potentially stemming from their involvement in emerging video-game related gambling products.
Positioning Human Microbiome DTC Tests On the Search for Health, Data and Alternatives Amid the Financialisation of Life
Authors: Widmer Alexandra 
Published: August 2021

Early during my fieldwork on the social life of the microbiome in Toronto, I was asked ‘Do you believe in microbiome testing?’ This question invited me to evaluate the science of the direct-to-consumer (DTC) test. In this Position Piece, I consider this question in a more expansive manner so as to position the test in its social and economic context. The distribution and public uptake of such a DTC test require scientific expertise but also marketing, capital investments, and clinical labour. This test requires consumers to do the work of stool collection and the reproductive labour of diet changes in their domestic spaces. I have learned that the microbiome is part of the quest for alternative ways of living and being healthy. Broadening the question to consider more than just the science expands the frame from one of scientific efficacy and individual consumption to one that considers the financialisation of health and the politics and environments of post-Pasteurian and post-industrial contexts.
Selection of optimal therapeutic modality for early-stage extranodal natural killer/T-cell lymphoma patients under the guidance of single-nucleotide polymorphism signature
Authors: Chen Zhe-Sheng , Yang Dong-Hua 
Published: August 2021

The therapeutic modalities of early-stage and advanced extranodal natural killer/T-cell lymphoma (NKTCL) patients are completely different. The former is mainly radiotherapy with or without chemotherapy, while the latter relies on chemotherapy-based systemic treatment.1,2 According to Ann Arbor staging system, approximately 70% of the NKTCL patients are classified as early-stage cases who are promising to be cured.3 Considering NKTCL is sensitive to radiation but may be resistant to chemotherapy, the radiotherapy is considered to be the most important treatment for some early-stage patients with a satisfactory local control rate and could be used alone.4 However, systemic recurrence after radiotherapy in a portion of NKTCL patients seriously affects their long-term survival, and the first-line treatment combined with radiotherapy and chemotherapy is considered necessary. Therefore, the use of radiotherapy alone in early-stage NKTCL is still a controversial issue.5,6
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Análisis de las prescripciones potencialmente inapropiadas en un servicio de medicina interna según los criterios de BEERS
Authors: Ankah Anka Rawi , Rojano Rada Jairo 
Published: August 2021

Objetivo: Análisis de las prescripciones potencialmente inapropiadas en un servicio de medicina interna según los criterios de Beers. Métodos: Se realizó un estudio de único centro, transversal, en pacientes de consulta externa, hospitalización y emergencia del servicio de Medicina Interna del Hospital Central del Instituto Venezolano de los Seguros Sociales (IVSS) “Dr. Miguel Pérez Carreño”, aplicando los criterios de Beers en pacientes mayores de 65 años. Resultados: La población estuvo representada por 300 pacientes, con una edad media de 73 ± 7, un 51,7% correspondió al sexo femenino, la mayoría de los pacientes provinieron de la unidad de consulta externa con 55,3% y presentaban un grado de instrucción en el nivel de primaria con 51,6% (n = 155). El antecedente personal más relevante fue la HTA con 69,7%. Los AINES se constituyeron los fármacos más formulados con 35.3%, el principal rango de prescripción inadecuada de medicamentos (PIM) se ubicó entre de 2 – 4 medicamentos con 53,5%, y la relación de PIM y multimorbilidad el principal grupo fue de 2 – 4 medicamentos con 50,7%, no siendo estadísticamente significativo (p= 0,310), Conclusión: Se observo que los pacientes > 65 años de consulta externa y hospitalización, tuvieron una elevada prescripción inadecuada de medicamentos según los criterios de Beers, con predominio del sexo femenino.
Outcomes of transecting urethroplasty in management of different types of bulbar urethral strictures: single center experience
Authors: Atwa Ayman Moussa , Hassan Ayman Ahmed , Orabi Samir Shabaan , Elgamal Samir Abdelhakim , Elgamal Osama Mostafa 
Published: August 2021

Background: The study aimed to evaluate the outcomes of transecting bulbar urethroplasty techniques used for management of bulbar urethral stricture as regards the success rate and sexual dysfunction.Methods: Our study was a prospective study and it was carried out at urology department Tanta university, Egypt. The study was approved our ethical committee and an informed consent was obtained from all participants. Thirty patients underwent transecting urethroplasty either excision and primary anastomosis (EPA) or augmented anastomotic urethroplasty. Assessment of the sexual function by sexual health inventory for men (SHIM) questionnaire and postoperatively. Retrograde urethrogram (RGU) and micturating cystourethrogram (MCUG) were performed by an experienced urological surgeon.Results: The age of studied patients ranged from 15-72 years with a mean of 41±13.87. The length of stricture ranged from 2-3 cm with a mean of 2.57±0.38. The stricture was non obliterative in 13 patients (43.3%), obliterative in 4 patients (13.3%) and near obliterative in 13 patients (43.3%). Anastomotic urethroplasty was carried out in 20 out of 30 patients (66.7%) and augmented anastomotic urethroplasty was carried out in 10 out of 30 patients (33.3%). The success rate was 90%. As regard erectile dysfunction, 5 patients reported erectile dysfunction (16.7%).Conclusions: Anastomotic urethroplasty of short segment bulbar strictures continues to have excellent success rates and durability, but some patients who undergo anastomotic urethroplasty experience de novo sexual dysfunction.
Association of risk stratification and mortality outcomes in patients of acute pulmonary embolism
Authors: Brahmbhatt Jit H. , Mansuri Zeeshan H. , Singhal Roopesh R. 
Published: August 2021

Background: To study the association of risk stratification and mortality outcomes of patients with high/intermediate risk acute pulmonary embolism who are given the guideline directed therapy after the diagnosis of pulmonary embolism.Methods: Prospective observational study of demographics, clinical profile, risk stratification, management and outcome of patients presenting with acute pulmonary embolism from October 2019to December 2020. Risk stratification was done as per ESC 2019 guidelines into high and intermediate categories, intermediate category patients were further stratified into intermediate-high and intermediate-low-risks.Results: 100 patients who were detected to have acute pulmonary thromboembolism with a mean age of 45.08 years with 60% being males were included in the study. There were 31 patients in high-risk group, 59 patients in intermediate-high subgroup, 10 patients in intermediate-low subgroup. Echocardiography was done in all patients. Outcome was relatively grave in these subgroups with overall mortality of 56 patients. 49 patients were thrombolysed with rTPA, 27patients with alteplase, 4 patients with streptokinase, 12patients who had contraindication to systemic thrombolysis were subjected to catheter directed thrombolysis and 8 patients were taken up for surgical embolectomy.Conclusions: Pulmonary embolism can present with unexplained dyspnea and atypical chest pain among other signs and symptoms. Early diagnosis, risk stratification and guideline directed prompt management can lead to favorable outcomes however; patients with high and intermediate risk at presentation are associated with higher mortality rate despite GDT.
The impact of COVID-19 on the postgraduate exit examination in a clinical subject
Authors: Diwan Arundhati , Singh V. P. , Karne Sampada , Barsode Supriya , Nadkarni Varad 
Published: August 2021

The year 2020 world experienced the rise of a new pandemic COVID-19 beginning. It started in India in early March. Maharashtra state saw a lockdown from March 2020. It has affected all the aspects of life in India including economy, patient care and medical education. The whole working system of hospitals had to be changed and most of the hospitals were divided into COVID and non-COVID parts. This article is an effort to study the perceptions of postgraduate medical students in the department of medicine on the exit examination at the end of three years of residency in a medical college in Pune. Along with the postgraduate student’s perceptions, views of examiners are also studied under four aspects protective measures during examination, assessment of knowledge using case scenarios, student’s experience of case presentation without physical presence of patients and overall satisfaction with the novel method of examination.
Indications and timing to perform tracheostomy in COVID-19 patients in intensive care unit: a review
Authors: Swain Santosh Kumar 
Published: August 2021

Coronavirus disease 2019 (COVID-19) is a fatal and evolving disease and associated with more complication such as respiratory failure and requirement of mechanical ventilation in intensive care unit (ICU). Tracheostomy is a commonly performed surgical procedure done at ICU for prolonged ventilation of the COVID-19 patients. The indications and timing to do tracheostomy on COVID-19 patients are controversial. The requirement of prolonged invasive mechanical ventilation in COVID-19 patients is placing to increased request to perform tracheostomy. The role of performing tracheostomy in COVID-19 patients is exactly not known. Currently, there is no clear-cut evidence for improvement of the clinical course of COVID-19 patients. However, it is confirmed that tracheostomy decreases the ICU stay. Tracheostomy is usually suggested for avoiding potential tracheal injury within 7 to 14 days. Currently, there is uncertainty for timing of tracheotomy, prognosis of the patients and safety of health care professionals. Enhanced personal protective equipment and optimized tracheostomy can make the procedure safe and beneficial in COVID-19 patients. The need of tracheostomy is increasing in current COVID-19 pandemic. We have to perform this surgical procedure in proper time with safe manner for benefit of the patients and health care professionals. This review article focuses on the indications and optimum timing for performing tracheostomy on COVID-19 patients in ICU.
The dilemma of prioritizing: are we ignoring the elderly
Authors: Behera Ashish 
Published: August 2021

Thie COVID-19 pandemic has brought about a lot of changes in the perspectives towards the aging persons of the community. It has also brought out the flaws of medical care to the table of discussions and the rational utilization of the limited resources available. Through this article, I want to raise the issue of prioritization of young over the old in limited-resource settings, especially in the developing countries