bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tapentadol as a drug of abuse – A preliminary report
Authors: Shivaprakash Prakrithi , Shukla Lekhansh , Joshi Sourabh , Mahadevan Jayant , Kandasamy Arun , Chand Prabhat K. , Benegal Vivek , Murthy Pratima 
Published: February 2025

Background:
Tapentadol is a dual action opioid analgesic with emerging data on abuse and diversion.

Aim:
This study describes tapentadol abuse, clinical presentation, and treatment patterns.

Methods:
We reviewed patients seeking help for tapentadol use (2017–2023) at a South Indian tertiary hospital. We collected data on sociodemographics, clinical profiles, and treatment, including buprenorphine dose and dose limiting side effects.

Results:
Of 933 opioid use disorder cases, 228 involved tapentadol. Most (89%) initiated opioid use with tapentadol, and 93% injected dissolved tablets. 80% were diagnosed with opioid dependence. Over half required inpatient treatment. 75% received buprenorphine, but tolerability was poor. The median first day dose was 0.8 mg (IQR = 0.4–2), and the maintenance dose was 4 mg (IQR = 2–8), with nausea being the main side effect.

Conclusion:
We can conclude that Tapentadol is prone to abuse and dependence. These patients have poor buprenorphine tolerability and receive low maintenance doses. Further research is needed on effective opioid agonist treatment for tapentadol dependence.
A Cross-sectional Study on Attitude, Practices and Perception of Medical Undergraduates towards E-learning
Authors: Sindhu B. M. , Rashmi B. M. , Kumbar Abhinandan S. , Manmathayya Shivakumar 
Published: February 2025

Abstract

Background:
E-learning has become an integral part of medical education. It equips students with the competencies needed to thrive in the field of rapidly evolving medical education. The present study was conducted to assess the attitudes and practices regarding ‘e-learning’ amongst undergraduate students and interns of a medical college.

Methods:
A cross-sectional study was conducted amongst MBBS students and interns of a medical college in Central Karnataka. The questionnaire was prepared in Google Forms and sent to all the students. Those who gave informed consent and returned fully filled pro forma were considered for data analysis.

Results:
The attitude and practice of e-learning amongst the respondents were satisfactory. One hundred sixty-four (95%) respondents opined that e-learning is user-friendly. Eighty-six (50%) students spent 2–4 h per day on e-learning using electronic gadgets. Furthermore, a matter of concern was the usage of electronic gadgets for more than 4 h per day for non-academic activities by 38 (22.1%) students. High cost of certain e-learning resources (48.6%), lack of proper information about the availability of various e-learning resources (24.9%), certain technical issues related to electronic gadgets (23.1%), concerns about quality and authenticity of various e-learning sites (24.9%) are some of the barriers and disadvantages specified by the students.

Conclusions:
The attitude and practice of e-learning amongst the respondents were satisfactory. Measures to be taken to reduce electronic gadget usage for non-academic activities. Resolving the barriers/disadvantages of e-learning can further enhance/facilitate e-learning amongst medical students.
A single-center experience of safety and effectiveness of adjustable intragastric balloon in patients with super obesity
Authors: Khan Mohammed S. , Alzanbagi Adnan , Tashkhandi Abdulaziz , Qurashi Laeeque A. , ElBahrawy Aly , Khogeer AlWahhaj , Alhazmi Ghadeer , Monshi Ghadeer , Shariff Mohammed K. 
Published: February 2025

Abstract

Background:
The Spatz3® Intragastric Adjustable Balloon (SAB) offers a novel approach to weight loss in super obese patients [body mass index (BMI) ≥50 kg/m2]. This study evaluates the safety, effectiveness, and predictors of success of SAB in this population.

Methods:
A retrospective study was conducted at King Abdullah Medical City, Makkah, Saudi Arabia, involving 94 patients with SAB implantation. Weight loss metrics (%EWL, %TBWL), complications, and predictors of adverse events were analyzed.

Results:
Eleven patients required early SAB removal due to severe symptoms. Complications included gastrointestinal bleeding (3.2%), gastric ulcer/erosion (27.7%), and deflation (5.3%). Significant weight loss was observed at 6 and 12 months. The mean absolute weight loss was 22.03 kg at 12 months, with %EWL of 19.27%. Early weight loss at 3 months predicted long-term success. SAB adjustments did not significantly impact outcomes. Post SAB, 57% of patients proceeded to laparoscopic sleeve gastrectomy (LSG) with rare postoperative complications (2.9%).

Conclusion:
SAB is safe and effective for patients with BMI ≥50 kg/m2, achieving significant weight loss at 12 months. Early weight loss predicts long-term success, and subsequent LSG can be performed without significant complications. Further research should explore long-term outcomes and comparative analyses.
Историк Н. И. Ульянов и теория «Москва — Третий Рим»
Authors: Базанов П.Н. 
Published: February 2025

Рассматриваются причины происхождения теории «Москва — Третий Рим». Показаны политические инсинуации вокруг данной религиозной доктрины. Дан обзор историософии вопроса. Анализируется творчество известного историка Н. И. Ульянова. Основное внимание уделяется двум вариантам его знаменитой работы «Комплекс Филофея». Опровергается миф «о русском империализме». Проанализированы отзывы современников на статью «Комплекс Филофея». Показана позиция современных историков и философов — узких специалистов в XVI в. Привлечены новые, впервые вводимые в научный оборот, архивные источники. Особенный интерес представляет анализ переписки Н. И. Ульянова и В. П. Никитина.
The reasons for the origin of the “Moscow — Third Rome” theory are considered. Political insinuations around this religious doctrine are shown. An overview of the historiosophy of the issue is given. The work of the famous historian N. I. Ulyanov is analyzed. The focus is on two versions of his famous work “The Philotheus Complex”. The myth “about Russian imperialism” is refuted. Feedback from contemporaries on the article “The Philotheus Complex” is analyzed. The position of modern historians and philosophers of narrow specialists in the 16th century is shown. New archival sources introduced into scientific circulation for the first time are involved. Of particular interest is the analysis of the correspondence of N. I. Ulyanov and V. P. Nikitina.
Славянский вопрос и дискуссии об основах российской внешней политики (1880‑е — начало 90‑х гг.)
Authors: Полунов А.Ю. 
Published: February 2025

В статье рассматриваются изменения в характере и основных направлениях реализации российской внешней политики в 1880‑е гг. Отмечается, что стимулом этих изменений было изменение ситуации на международной арене — прежде всего, ухудшение отношений со славянскими государствами Балкан, получившими или закрепившими независимость благодаря России по итогам войны 1877–1878 гг. В сложившейся ситуации часть общественных деятелей и публицистов заявляла о необходимости придать внешней политике государства сугубо прагматический характер, отказаться от идеологических мотивов — в частности, от представлений, что на России лежит обязанность оказывать помощь зарубежным «младшим братьям». Однако утвердиться такая установка не могла. В деятельности России на международной арене по-прежнему присутствовали идеологические компоненты. Однако теперь в качестве объектов покровительства рассматривались не зарубежные славяне, а народы более отдаленных регионов, в частности, эфиопы. Поиск новых «младших братьев» стал важной составляющей российской внешней политики конца XIX — начала XX в. Последствия подобной деятельности были неоднозначны, однако нельзя отрицать, что она опиралась на глубоко укорененные стереотипы общественного сознания и оставила глубокий след в истории России.
The article examines the changes in the nature and main directions of Russian foreign policy in the 1880s. The changes under discussion were stimulated by the new situation on the international stage, first of all, the deterioration of relations with the Slavic states of the Balkans, which gained or consolidated their independence thanks to Russia following the war of 1877–1878. In this situation, some public figures and publicists declared the need to give the foreign policy of the state a purely pragmatic character, to abandon ideological motives — in particular, the notion that Russia is obliged to provide assistance to foreign “younger brothers”. However, such an attitude could not be established. Russia’s activities in the international arena still had ideological components. However, now, not foreign Slavs were considered as objects of patronage, but the peoples of more distant regions, in particular, the Ethiopians. The search for new “little brothers” became an important component of Russian foreign policy in the late nineteenth and early twentieth centuries. The consequences of such activities were ambiguous, but it cannot be denied that it was based on deeply rooted stereotypes of public consciousness and left a deep mark on the history of Russia.
Transforming Online Retail: The Impact of Augmented and Virtual Reality on Consumer Engagement and Experience in E-Commerce in the Context of the Sustainable Development Goals (SDG)
Authors: Cunha Maria Nascimento 
Published: February 2025

Purpose: This study aims to understand how these technologies enhance consumer experiences. The study also explores the role of AR and VR in promoting responsible consumption and sustainable production (SDG 12), reducing waste through better product visualization, and fostering digital inclusivity (SDG 9).

Design/Method/Approach: The methodologies analyzed include experimental designs, market analyses, and conceptual frameworks assessing the integration of AR and VR technologies in online retail.

Findings: The findings indicate that AR enhances online shopping through features such as virtual try-ons and spatial placement visualization, reducing return rates and increasing purchase confidence.

Theoretical Implications: This study contributes to consumer behavior research by applying value perception models, immersive technology frameworks, and engagement metrics to the e-commerce landscape.

Practical Implications: The research underscores the strategic importance of integrating AR and VR into digital marketing and e-commerce platforms. It suggests leveraging AR for product categories requiring spatial interaction and VR for high-detail product exploration. The study provides actionable insights for businesses looking to enhance online shopping experiences through immersive technologies while aligning with SDG objectives.

Originality/Value: This study offers a comprehensive synthesis of AR and VR applications in e-commerce, highlighting their potential to reshape online shopping.

Research Limitations/Future Research: Future research should explore the long-term effects of AR and VR adoption on consumer trust, loyalty, and behavioral changes and also examine the role of these technologies in achieving SDG targets related to responsible consumption and production (SDG 12) and industry innovation (SDG 9).
Hubungan Gejala Gangguan Stres Pascatrauma dengan Kualitas Hidup Anggota Relawan Bencana Banjir di Putussibau Kalimantan Barat
Authors: Vicky Sutrisno Kusuma Jasmine , Maria Theresa Ria , Maya Savitri Pritha , Nugrohowati Nunuk 
Published: February 2025

Background: PTSD occurs when a person undergoes life-threatening events like war, terrorism, accidents, abuse, or natural disasters. It can greatly impact an individual's well-being, causing harm to their physical, mental, social, and environmental health. Purpose: The aim of this research is to uncover the connection between PTSD symptoms and the quality of life. Methods: This study used a quantitative approach with descriptive characteristics and a cross-sectional design. The number of participants was 135 people who volunteered to be involved in flood disaster management operations. The research location was in Putussibau. Results: According to the possibility of PTSD, about 32.6% of respondents were suspected of experiencing PTSD symptoms. In terms of physical health, 34.1% of respondents had a moderate level, in terms of psychological well-being, 34.8% of respondents had a moderate level, in terms of social relationships, 27.4% of respondents had a poor level, and in terms of relationships with the environment, 33.3% of respondents had a good level. The results of the bivariate test showed that the p value had a value greater than 0.05. Conclusion: Due to the frequent flooding in Putussibau, volunteers may experience adjustments. In addition, engagement in regular exercise may be a factor that supports a good quality of life for respondents. These factors may explain why no correlation was found between the two variables.
Some More Results on Neighborhood Connected Two Out Degree Equitable Domination Number of Graphs
Authors: M.S.Mahesh  
Published: February 2025

For any graph G, the out degree of a vertex v with respect to D is denoted by and it is defined by). A sub set D of V(G) is said to be two out degree equitable dominating set if D is dominating set and for any two vertices such that The minimum number of vertices in two out degree equitable dominating set is called two out degree equitable domination number and it is denoted by Based on the above concept of out degree we introduce a new domination parameter called neighborhood connected two out degree equitable domination number and study this domination number for some standard graphs In this paper the proposed domination number verified for some new special graphs and semitotal point graph of some general graphs.
Systematic Investment Plan vs. Lumpsum Investment: A Comparative study across Time and Indexes
Authors: Pushkar Dilip Parulekar  
Published: February 2025

Introduction: SIP is based on the logic of rupee cost averaging wherein regular periodic investments are made (generally monthly) as LI which means one time investment There is always a debate between active and passive investing. Even though some active investors might outperform passive investors, there will be balancing underperformers as well. Considering transaction cost and risk adjusted returns passive investors tend to outperform the active investors over the longer time horizon.
Objectives: This paper compares success of two popular methods of passive investing that could be used by retail investors for investing in Indian stock markets viz. Systematic Investment Plan (SIP) vs. Lumpsum Investment (LI). The paper calculates risk and return for buy and hold strategy for the period of 5 ,10 and 15 years in various indices.
Methods:The study was based on monthly data for seven indices over a period of 20 years from 1st October 2004 to 1st October 2024. There were four broad-based indices viz. Nifty 50, Nifty 100, Nifty 200 and Nifty 500. The other three were sectorial indices viz. Nifty AUTO, Nifty BANK and Nifty FMCG. They were evaluated on various time frames of 5 years, 10 years and 15 years. The evaluation parameters were Extended Internal Rate of return adjusted for investing time (XIRR) for SIP and Compounded Annual growth rate (CAGR) for LI. The two methods were evaluated based on Maximum, Minimum, Average, Standard deviation, Variance of XIRR and CAGR numbers. Comparative analysis was done using t-Test: Paired two Sample for means. The papers cover various market cycles and investment horizons commonly recommended for retail investors.
Results: Out of the 21 combinations of (3 timeframes * 7 indexes) SIP was better than LI in terms of risk related parameters in 19 combinations. However, in terms of returns there were many combinations wherein LI was better than SIP. Contrary to the popular belief, there was no conclusive evidence that SIP was better than LI particularly for large cap index like Nifty 50 and defensive index like Nifty FMCG across timeframes. For the timeframe of 5 years and 10 Years SIP was better as compared to LI for Nifty 200, Nifty 500, Nifty AUTO and Nifty BANK index. However, based on returns and absolute amount LI was better as compared to SIP investment.
Conclusions: Passive investing in Index funds is highly recommended for retail investors because of transaction costs in Indian mutual funds. In the case of index funds, they can choose broad based funds or sectorial funds based on their risk appetite and time horizon and SIP or LI as a style of investment.
Application of Wearable Devices in Diabetes Management
Authors: Du Zijing , Zhang Feifan , Ge Yifei , Liu Yijiang , Yu Honghua , Wang Yong , Dalan Rinkoo , Shen Xiaotao 
Published: February 2025

Review
Application of Wearable Devices in Diabetes Management

Zijing Du 1,2,†, Feifan Zhang 1,†, Yifei Ge 1, Yijiang Liu 3, Honghua Yu 2, Yong Wang 4, Rinkoo Dalan 1,5, and Xiaotao Shen 1,3,*

1 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 636921, Singapore
2 Guangdong Eye Institute, Department of Ophthalmology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China
3 School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, 639798, Singapore
4 College of Computing and Data Science, Nanyang Technological University, Singapore, 637616, Singapore
5 Department of Endocrinology, Tan Tock Seng Hospital, Singapore, 308433, Singapore
* Correspondence: xiaotao.shen@ntu.edu.sg
† These authors contributed equally to this work.

Received: 17 December 2024; Revised: 20 January 2025; Accepted: 12 February 2025; Published: 19 February 2025

Abstract: Diabetes mellitus poses a significant global health challenge, impacting hundreds of millions worldwide. Effective management and prevention of complications rely on dynamic, real-time glucose monitoring. This review provides a comprehensive overview of the rapidly evolving landscape of wearable technologies for glucose monitoring and diabetes care, with a focus on cutting-edge advancements and their integration with artificial intelligence (AI) and multi-omics data. We explore diverse glucose monitoring approaches, including continuous glucose monitors (CGMs) and smartwatches, highlighting their contributions to tracking physical activity, food intake, medication adherence, and direct glucose measurements. Our emphasis is placed on the role of AI systems in enabling predictive analytics and personalized care, as well as the integration of wearable data with multi-omics insights—spanning genomics, proteomics, and gut microbiome analyses—to enhance understanding of individual glucose metabolism. Given the challenges of existing methods, such as invasiveness, accuracy, and accessibility, we discuss future directions, including the potential of smart glasses, advanced AI models, and seamless data integration, to revolutionize diabetes management. This review offers valuable insights into how wearable technologies, AI, and multi-source data analysis are shaping the future of precision diabetes care.
Intrinsically Multi-Color Device Based on Dynamic Cooperation of Molecular Switches and Metal Ions
Authors: Li Min , Wang Shuo , Shen Ruipeng , Xie Yigui , Zhang Yu-Mo , Zhang Sean Xiao-An 
Published: February 2025

Article
Intrinsically Multi-Color Device Based on Dynamic Cooperation of Molecular Switches and Metal Ions

Min Li, Shuo Wang*, Ruipeng Shen, Yigui Xie, Yu-Mo Zhang and Sean Xiao-An Zhang*

State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.
*Address correspondence to: wangshuo@jlu.edu.cn and seanzhang@jlu.edu.cn
Received: 6 January 2025; Revised: 5 January 2025; Accepted: 11 February 2025; Published: 19 February 2025

Abstract: Multi-color electrochromic material is a long-expected and extremely challenging material, which is important for electrochromic technology to be applied in adaptive camouflage, augmented reality, transparent display, etc. Here, an intrinsically multi-color indirect-electrochromic material based on supramolecular interactions of unusual multi-state molecular switch and metal ion was developed, combining the advantage of multi-state of molecular switch and chemical stability of metal ion. Related prototype device, with transparent intrinsic colorless, magenta, cyan and various mixed colors, have been explored and demonstrated. The mechanism was based on the dynamic coordination of multiple metal ions and single-molecular-dual-switches within fragile supramolecular clusters. Wherein, the color and lightness could be controlled simply by the bias applied, with abilities such as transmittance change (41%), coloring time (7.8 s), coloration efficiency (>100 cm2/C), and reversibility (>600 test cycles, no abnormal changes). The prototype device was fabricated to show the potential to be used in low energy consumption display.
Tempos e lugares de Batuque: manifestações em uma cidade do interior paulista
Authors: Silva Elisabete de Fatima Farias , Faria Monique Marques 
Published: February 2025

Em Rio Claro/SP, Tambu e Congada são manifestações do Batuque que expressam valores de um com-viver pelos tambores, a partir da matriz africana diaspórica em acordos e tensões com outras racionalidades. Historicamente, a realização dos encontros de Batuque passou por diferentes processos, demarcando tempos-lugares-corpos. Entre os “Batuques de antigamente” e os “Batuques de agora”, investiga-se pelos relatos orais: Quais os lugares permitidos/proibidos aos corpos-batuqueiros e que estratégias são realizadas, no plano do urbano, para esconder, esquecer e deslocar tais corpos e, por outro lado, quais são as respostas de r-existência a isso? Compreender esses processos consiste em registrar e pensar a geograficidade das relações estabelecidas entres os sujeitos e lugares que perfazem e existem na manifestação do fenômeno e, assim, produzir uma Geografia que se preocupe com a realidade latino-americana voltada ao cotidiano e aos mundos de sentidos que se situam na encruzilhada de matrizes, tempos, lugares e corpos.
SABERES E CONHECIMENTOS DOCENTES: olhares sobre o Conhecimento Pedagógico do Conteúdo do professor de Geografia
Authors: Pereira Valéria Rodrigues , Lopes Claudivan Sanches 
Published: February 2025

O presente artigo refere-se ao projeto de pesquisa “Os saberes dos professores de Geografia” desenvolvido na Universidade Federal de Mato Grosso Sul, Campus de Três Lagoas, com finalidade de conhecer o repertório de saberes mobilizados por professores de geografia. A investigação foi realizada com profissionais de ensino, egressos do curso de Geografia desta universidade e em exercício em escolas públicas. Sob a perspectiva geográfica, abordamos as pesquisas relacionadas ao saber docente e destacamos, por meio de Shulman (2014), a Base de Conhecimentos e o Conhecimento Pedagógico do Conteúdo-CPC, entendido como a maneira especial em que os professores dentro de seus campos de conhecimentos transformaram o conteúdo para ensinar. Os resultados alcançados confirmaram a existência de fontes de conhecimentos que sustentam a atuação dos professores, possibilitando compreensão dos conteúdos, orientação nas escolhas didáticas, encaminhamento de discussões, desenvolvimento da aula e de atividades com alunos, entre outras questões pertinentes ao ensino. Palavras-chave: saber docente; conhecimento pedagógico do conteúdo; base de conhecimentos