bluuebunny/crossref_metadata_2025_split huggingface dataset:
Attitudes toward genomics and precision medicine
Authors: DuBois James M. , Mozersky Jessica , Antes Alison , English Tammy , Parsons Meredith V. , Baldwin Kari 
Published: April 2021

AbstractPurpose:This paper reports on a novel measure, attitudes toward genomics and precision medicine (AGPM), which evaluates attitudes toward activities such as genetic testing, collecting information on lifestyle, and genome editing – activities necessary to achieve the goals of precision medicine.Discussion:The AGPM will be useful for researchers who want to explore attitudes toward genomics and precision medicine. The association of concerns about precision medicine activities with demographic variables such as religion and politics, as well as higher levels of education, suggests that further education on genomic and precision activities alone is unlikely to shift AGPM scores significantly.Methods:We wrote items to represent psychological and health benefits of precision medicine activities, and concerns about privacy, social justice, harm to embryos, and interfering with nature. We validated the measure through factor analysis of its structure, and testing associations with trust in the health information system and demographic variables such as age, sex, education, and religion.Results:The AGPM had excellent alpha reliability (.92) and demonstrated good convergent validity with existing measures. Variables most strongly associated with higher levels of concern with precision medicine activities included: regular religious practice, republican political leanings, and higher levels of education.
The essential coexistence phenomenon in Hamiltonian dynamics
Authors: CHEN JIANYU , HU HUYI , PESIN YAKOV , ZHANG KE 
Published: April 2021

AbstractWe construct an example of a Hamiltonian flow
$f^t$
on a four-dimensional smooth manifold
$\mathcal {M}$
which after being restricted to an energy surface
$\mathcal {M}_e$
demonstrates essential coexistence of regular and chaotic dynamics, that is, there is an open and dense
$f^t$
-invariant subset
$U\subset \mathcal {M}_e$
such that the restriction
$f^t|U$
has non-zero Lyapunov exponents in all directions (except for the direction of the flow) and is a Bernoulli flow while, on the boundary
$\partial U$
, which has positive volume, all Lyapunov exponents of the system are zero.
The modern rule of releases
Authors: Whayman Derek 
Published: April 2021

AbstractThis paper considers the history and nature of the ‘modern rule of releases’, concerning compromises to settle or preclude litigation. The rule holds that only matters the parties had contemplated as well as what they intended to release will in fact be released, even if the compromise has been made in the most general terms. Thus the rule is engaged when the releasor executes a general release but does not appreciate the existence of some of the claims the words used purport to release. This paper shows how the rule is a confusion of different conceptual bases and lines of authority and was created by accidentally muddling them together. It argues that, despite this, it successfully straddles both bases, functions well conceptually and serves a vital role.
VARRO AND POMPEY: SOME MORE (MULTIPLE) HEBDOMADS?
Authors: Geiger Joseph 
Published: April 2021

AbstractThis article argues that a group of fourteen female statues seen in the Theatre of Pompey in Rome by Tatian belonged to Greek female poets. This group, along with the statues representing the fourteen nationes vanquished by Pompey, and certain groups of statues in the Forum of Augustus should all be ascribed to the influence of the Hebdomades of Pompey's familiaris Varro.
Global Board Reforms and the Pricing of IPOs
Authors: Chen Yangyang , Goyal Abhinav , Zolotoy Leon 
Published: April 2021

AbstractWe document that global board reforms are associated with a significant reduction in the underpricing of initial public offerings (IPOs). The effect is amplified for IPOs with greater agency problems and mitigated for IPOs certified by reputable intermediaries, IPOs with greater disclosure specificity, and IPOs in countries with better shareholder protection and stringent financial reporting regulations. Furthermore, global board reforms have led to an improvement in the long-term market performance, proceeds, and subscription level of IPOs and have enhanced board independence in the issuing firms. Our findings suggest that global board reforms have strengthened board oversight in the issuing firms, leading to less underpriced IPOs.
Intergenerational transmission of suicide attempt in a cohort of 4.4 million children
Authors: Ranning Anne , Uddin Md Jamal , Sørensen Holger J. , Laursen Thomas Munk , Thorup Anne A. E. , Madsen Trine , Nordentoft Merete , Erlangsen Annette 
Published: April 2021

AbstractBackgroundThe association between suicide attempts (SAs) in parents and children is unclear, and risk indicators for intergenerational transmission remain undocumented. We aimed to assess this association, considering the child's developmental period at the time of parents' attempted suicide, and the parental relation.MethodsUsing a prospective cohort design, nationwide population data were linked to the Psychiatric Central Register and National Patient Register for all individuals aged 10 years or older living in Denmark between 1980 and 2016. We assessed incidence rate ratios (IRRs) and cumulative hazards for children's first SA.ResultsIn a cohort of 4 419 651 children, 163 056 (3.7%) had experienced a parental SA. An SA was recorded among 6996 (4.3%) of the exposed children as opposed to 70112 (1.6%) in unexposed individuals. Higher rates were noted when a parental SA occurred during early childhood (0 ⩽ age < 2) [IRR, 4.7; 95% confidence interval (CI) 4.2–5.4] v. late childhood (6 ⩽ age < 13) (IRR, 3.6; 95% CI 3.4–3.8) when compared to those unexposed. Children exposed prior to age 2 had the highest rates of all sub-groups when reaching age 13–17 (IRR, 6.5; 95% CI 6.0–7.1) and 18–25 years (IRR, 6.8; 95% CI 6.2–7.4). Maternal SA (IRR, 3.4; 95% CI 3.2–3.5) was associated with higher rates than paternal (IRR, 2.8; 95% CI 2.7–2.9).ConclusionParental SA was associated with children's own SA. Exposure during early developmental stages was associated with the highest rates. Early preventive efforts are warranted as is monitoring of suicide risk in the children from age 13.
Continuum beliefs and mental illness stigma: a systematic review and meta-analysis of correlation and intervention studies
Authors: Peter Lina-Jolien , Schindler Stephanie , Sander Christian , Schmidt Silke , Muehlan Holger , McLaren Thomas , Tomczyk Samuel , Speerforck Sven , Schomerus Georg 
Published: April 2021

AbstractBackgroundPromulgating a continuum model of mental health and mental illness has been proposed as a way to reduce stigma by decreasing notions of differentness. This systematic review and meta-analysis examines whether continuum beliefs are associated with lower stigma, and whether continuum interventions reduce stigma.MethodsFollowing a pre-defined protocol (PROSPERO: CRD42019123606), we searched three electronic databases (PubMed, Web of Science, and PsycINFO) yielding 6726 studies. After screening, we included 33 studies covering continuum beliefs, mental illness, and stigma. Of these, 13 studies were included in meta-analysis.ResultsContinuum beliefs are consistently associated with lower stigma. Interventions were effective at manipulating continuum beliefs but differ in their effects on stigmatising attitudes.ConclusionsWe discuss whether and to what extent attitudes towards people with mental illness can be improved by providing information on a mental health-mental illness continuum. It appeared to be relevant whether interventions promoted a feeling of ‘us’ and a process of identification with the person with mental illness. We discuss implications for the design of future interventions.
Simplified olfactory reminiscence to help maintain the mental health in community-dwelling older adults
Authors: Hanaoka Hideaki , Muraki Toshiaki , Kaneko Fumiko , Yamane Shingo , Okamura Hitoshi 
Published: April 2021

AbstractThe purpose of this study was to examine the effects of simplified reminiscence practice using olfactory stimuli on depression and cognitive function in community-dwelling older adults in Japan. Accordingly, 61 individuals were randomly divided into two groups. In the intervention group, 12 sessions of reminiscence were performed using olfactory cards. In the control group, reminiscence sessions were similarly performed, but with language cards. The Geriatric Depression Scale-15 (GDS-15) was used to measure mental health status and the Five Cognitive Test was used to measure cognitive function at baseline and after completion of the intervention. The final sample included 27 participants in the intervention group and 23 participants in the control group. Basic characteristics of the participants at baseline were compared and a significant difference was observed between the two groups in age (p = 0.029). Repeated-measures analysis of covariance with age as the covariate revealed a significant interaction between time and group on the GDS-15 (p = 0.04). Furthermore, a before and after comparison using a paired t-test showed a significant difference only in the intervention group (p = 0.01). The results of this study suggest that simplified reminiscence practice using olfactory cards could serve as an intervention to help maintain the mental health of community-dwelling older adults.
Distributed task allocation with critical tasks and limited capacity
Authors: Zhang An , Yang Mi , Bi Wenhao , Gao Fei 
Published: April 2021

AbstractThis paper considers the task allocation problem under the requirement that the assignments of some critical tasks must be maximized when the network capacity cannot accommodate all tasks due to the limited capacity for each unmanned aerial vehicle (UAV). To solve this problem, this paper proposes an extended performance impact algorithm with critical tasks (EPIAC) based on the traditional performance impact algorithm. A novel task list resizing phase is developed in EPIAC to deal with the constraint on the limited capacity of each UAV and maximize the assignments of critical tasks. Numerical simulations demonstrate the outstanding performance of EPIAC compared with other algorithms.
Value Conservatism and its Challenge to Consequentialism
Authors: Sass Reuben 
Published: April 2021

AbstractG. A. Cohen's value conservatism entails that we ought to preserve some existing sources of value in lieu of more valuable replacements, thereby repudiating maximizing consequentialism. Cohen motivates value conservatism through illustrative cases. The consequentialist, however, can explain many Cohen-style cases by taking extrinsic properties, such as historical significance, to be sources of final value. Nevertheless, it may be intuitive that there's stronger reason to preserve than to promote certain sources of value, especially historically significant things. This motivates an argument that the weights of our reasons to preserve such things are especially strong relative to the amounts of value they bear. The value conservative can then explain these intuitions in non-consequentialist terms. There may be reason to preserve historically significant things as a matter of recognition respect for a cultural and historical heritage, or because it is virtuous to cultivate the right kind of connection with such a heritage.
Impact of childhood maltreatment and resilience on behavioral and neural patterns of inhibitory control during emotional distraction
Authors: Demers Lauren A. , Hunt Ruskin H. , Cicchetti Dante , Cohen-Gilbert Julia E. , Rogosch Fred A. , Toth Sheree L. , Thomas Kathleen M. 
Published: April 2021

AbstractExposure to childhood maltreatment (CM) may disrupt typical development of neural systems underlying impulse control and emotion regulation. Yet resilient outcomes are observed in some individuals exposed to CM. Individual differences in adult functioning may result from variation in inhibitory control in the context of emotional distractions, underpinned by cognitive–affective brain circuits. Thirty-eight healthy adults with a history of substantiated CM and 34 nonmaltreated adults from the same longitudinal sample performed a Go/No-Go task in which task-relevant stimuli (letters) were presented at the center of task-irrelevant, negative, or neutral images, while undergoing functional magnetic resonance imaging. The comparison group, but not the maltreated group, made increased inhibitory control errors in the context of negative, but not neutral, distractor images. In addition, the comparison group had greater right inferior frontal gyrus and bilateral frontal pole activation during inhibitory control blocks with negative compared to neutral background images relative to the CM group. Across the full sample, greater adaptive functioning in everyday contexts was associated with superior inhibitory control and greater right frontal pole activation. Results suggest that resilience following early adversity is associated with enhanced attention and behavioral regulation in the context of task-irrelevant negative emotional stimuli in a laboratory setting.
A new portrait type for Faustina the Younger
Authors: Beckmann Martin 
Published: April 2021

AbstractThis note identifies a new portrait type of Faustina the Younger, which appears on medallions and on a single aureus. On medallions the type appears in a single, closely die-linked group, indicating a synchronous emission. I suggest that this emission should be placed in a prominent gap in the (dated) medallion issues of Antoninus Pius and Marcus Aurelius, which in turn dates this newly identified portrait of Faustina to 153/4 CE.
T1 mapping and conditional survival in paediatric dilated cardiomyopathy with advanced heart failure
Authors: Raj Shashi , Kothari Richa , Arun Kumar N , Sigamani Alben , Raj Vimal 
Published: April 2021

AbstractMyocardial fibrosis is associated with adverse events in idiopathic dilated cardiomyopathy. Cardiac MRI with late gadolinium enhancement can detect myocardial fibrosis. We evaluated the conditional survival of children and adolescents based on native T1 mapping (combined proton signal from myocytes and interstitium prior to contrast administration by the measurement of myocardial and blood relaxation time) as a means to assess myocardial fibrosis. This retrospective case–cohort over a 3-year period included all consecutive patients (aged ≤ 21 years) with advanced heart failure from dilated cardiomyopathy (echocardiographic left ventricular ejection fraction ≤ 45% and NYHA class ≥ 2) who underwent cardiac MRI.Conditional survival (follow-up ≥ 6 months after cardiac MRI) was assessed to include NYHA functional class and time to event (death or heart transplantation). A total of 57 patients (mean age 11.7 ± 6.1 years; 58% male) had a median NYHA Class III (31/57) and median left ventricular ejection fraction 25% (20–38%). Survival data were available in 82% patients (46/57) and the crude mortality rate was 24% (11/46) and one patient (2%) underwent heart transplantation. The median native T1 was elevated at 1351 ms (95% CI 1332, 1394) and it showed no difference between the groups who survived to those who died. Performing a multilevel regression analysis on prognosis failed to predict 6-month conditional survival.
Severe conduit stenosis in a patient with Fontan circulation with a Y-shaped Dacron conduit
Authors: Takajo Daiji , Balakrishnan Preetha L. , Aggarwal Sanjeev 
Published: April 2021

AbstractConduit stenosis is a major, albeit rare, complication following the Fontan palliation. A single-baffle conduit with polytetrafluoroethylene is widely used for an extracardiac type Fontan palliation. A polyethylene terephthalate conduit (Dacron) is sometimes used for the conduit when more flexibility is required. A Y-shaped conduit is rarely used, but it may reduce the energy loss and achieve better hepatic flow distribution. Data on the long-term patency and complications when using a Y-shaped Dacron conduit is lacking. We report a case of a severely stenotic Y-shaped Dacron conduit in a patient who underwent extracardiac Fontan palliation.
Detachable coil embolisation for iatrogenic femoral arteriovenous fistula in patients with CHDs
Authors: Sugiyama Hisashi , Asagai Seiji 
Published: April 2021

AbstractWe present two cases of patients with iatrogenic femoral arteriovenous fistula who underwent successful embolisation using three-dimensional shape detachable coils. A 49-year-old male with Tetralogy of Fallot had arteriovenous fistula which developed from the common femoral artery to the femoral vein with an aneurysm and a 17-year-old female with single ventricle after total-cavo-pulmonary-connection had two arteriovenous fistulas which developed from the internal iliac artery to the femoral vein. A total of six and seven pieces of detachable coils were necessary for complete occlusion, respectively. No complications were recorded. The advantage of the detachable coil is a wide variation and repositioning until the coil achieves good stabilisation and an ideal configuration.
HECKE OPERATORS AND THE COHERENT COHOMOLOGY OF SHIMURA VARIETIES
Authors: Fakhruddin Najmuddin , Pilloni Vincent 
Published: April 2021

AbstractWe consider the problem of defining an action of Hecke operators on the coherent cohomology of certain integral models of Shimura varieties. We formulate a general conjecture describing which Hecke operators should act integrally and solve the conjecture in certain cases. As a consequence, we obtain p-adic estimates of Satake parameters of certain nonregular self-dual automorphic representations of

$\mathrm {GL}_n$
.
Do cost-share programs increase cover crop use? Empirical evidence from Iowa
Authors: Sawadgo Wendiam , Plastina Alejandro 
Published: April 2021

AbstractCover crops can generate both on-farm and water-quality benefits. However, their use in Iowa remains subdued, partly due to implementation costs faced by farmers. We tested the hypothesis that monetary incentives through cost-share programs are effective at increasing the area of farmland planted to cover crops in Iowa, as opposed to the alternative in which the participants of cost-share programs would have planted the same cover-crop acreage in the absence of payment. We found that cost-share payments induced a 15 percentage-point expansion in cover-crop acreage beyond what would have been planted in the absence of payment, among farmers who participated in cost-share programs. The estimated additionality rate was 54%, suggesting at least half of cost-share expenditures funded cover-crop acreage that would not have been planted without payment. Furthermore, we estimated the public cost to reduce nitrogen loads to Iowa waterways via cover crop, beyond what would have occurred in the absence of cost-share programs, to be $1.72–$4.70 lb−1N ($3.79–$10.36 kg−1N). Farmers absorbed about 70% of those costs as private losses, and cost-share payments offset the remaining 30%. Although the additionality rate estimated in this study is less than what has been found in other states, the cost-share programs in Iowa have been relatively cost-effective, due to their lower payment rate.
Characteristic Features of the Clouds Producing Thunderstorm Ground Enhancements
Authors: Svechnikova E. K. , Ilin N. V. , Mareev E. A. , Chilingarian A. A. 
Published: April 2021

AbstractThunderstorm ground enhancements (TGEs) are fluxes of energetic particles multiplied in thunderclouds, which may be registered by ground‐based detectors. Using the Weather Research and Forecasting (WRF) Model, the state of the atmosphere with a 1‐km horizontal resolution is modeled for convective events accompanied by TGEs observed at the high altitude Aragats Research Station in Armenia (40.47 N, 44.18 E, 3,200 m above sea level). By comparing the data obtained in observations with the results of simulations using a microphysical parameterization for WRF, a technique is developed for estimating charge distribution parameters. A typical charge distribution in a TGE‐producing cloud is found to be well approximated by a two‐layered charge structure with a lower positive charge region formed by graupel particles and an upper negative charge region formed by snow particles. The characteristic charge density is 0.01 nC/m3 for the graupel cluster and −0.02 nC/m3 for the snow cluster. A vertical distance of about 1–2 km between the lower positive and upper negative layers is sufficient for the development of an energetic particle avalanche.
Lockdown Measures Which Reduced Greenhouse Gas Emissions With Little Negative Impact on Quality of Life
Authors: Niemi Maria , Skelton Alasdair , Noone Kevin , Olsson Mats J. 
Published: April 2021

AbstractLockdown measures in response to the new Covid‐19 virus have caused the largest ever fall of annual greenhouse gas emissions. A key question that we attempt to answer in this study is which, if any, of these measures can be productively encouraged post‐lockdown in efforts to sustain at least part of this reduction in emissions. Sweden is uniquely suited for our study because the voluntary nature of lockdown in Sweden allowed us to assess the level of compliance to recommendations and its effects on greenhouse gas emissions. First, we assessed the change of perceived quality of life (QOL) among 746 individuals from Stockholm region due to adhering to lockdown measures. Second, we calculated the associated change of annual per capita greenhouse emissions. We found that avoiding travel for work, avoiding purchasing, and avoiding restaurants had the least negative effect on QOL, and at the same time the largest positive effect on carbon dioxide equivalent (CO2e) emission reductions. We conclude that these are potential leverage points for stimulating behavioral change that has a positive climatic impact.
Structure and Variability of Abyssal Current in Northern South China Sea Based on CPIES Observations
Authors: Zheng Hua , Zhang Chuanzheng , Zhao Ruixiang , Zhu Xiao‐Hua , Zhu Ze‐Nan , Liu Zhao‐Jun , Wang Min 
Published: April 2021

AbstractThe abyssal current is important for water renewal and energy conversion in the deep South China Sea (SCS), and it potentially contributes to the upper and middle circulations. A mooring array including 11 current and pressure‐recording inverted echo sounders was deployed in the northern SCS between July 2016 and April 2019 to observe large‐scale and long‐term abyssal currents. The yearly averaged current flows southwestward following the boundary with a maximum velocity of 2.25–2.52 cm/s. The spatial structure exhibits a weaker and wider current in the north, where topography is subdued, whereas the current enhances and narrows on the steep slopes. The southwestward current is strong in the summer and autumn but is insignificant in the winter and spring. In the autumn, the current is narrower and closer to the boundary than that in the summer, and a northeastward countercurrent is found ∼60 km away from the western boundary. The southwestward and northeastward currents constitute the cyclonic circulation. Drastic temporal variability is observed in the deep ocean. The abyssal current is dominated by semidiurnal tides, diurnal tides, and near‐inertial waves (NIWs) in the high‐frequency band. Bursts of NIWs are observed in the deep ocean after two typhoons, and the NIWs propagate southwestward at a velocity of 2.4 m/s. The low‐frequency band is dominated by a westward‐propagating 70‐day fluctuation following the characteristics of topographic Rossby waves.