bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pembinaan Panti Rehabilitasi
Authors: Ananda Ramon , Rosyidi Hamim 
Published: August 2021

Hilangnya kebermaknaan hidup bagi warga binaan panti merupakan fenomena yang sering terjadi di sekitar masyarakat kita. Warga binaan panti yang merupakan individu lanjut usia (lansia) sering mengalami penyebab yang kurang menyenangkan ketika harus tinggal di panti, sering mengalami tekanan baik secara fisik maupun psikologis. Pendampingan dan pemberdayaan yang dilakukan di UPT Pelayanan Sosial Tresna Wherda ini lebih kepada memperkuat kapasitas diri melalui kebermaknaan hidup melalui optimalisasi nilai-nilai religiusitas yang ada pada diri warga binaan tersebut. Metode yang digunakan terhadap pendampingan ini yaitu pendekatan Asset-Based Community-driven Development (ABCD). Pendekatan ini sangat tepat jika digunakan untuk mengoptimalkan potensi-potensi yang ada dalam diri individu terutama potensi religiusitas untuk menemukan kebermaknaan hidup serta dapat secara efektif menggali dan menemukan makna dari kehidupan yang mulai memudar ketika terjadi proses adaptasi yang sulit. Hasil dari pendampingan dan pemberdayaan ini terhadap warga binaan di pusat rehabilitasi yaitu adanya rasa optimisme yang tinggi dalam menyongsong kehidupan walaupun mereka jauh dari keluarga, dapat merasakan Allah SWT sebagai Rahman dan Rahim ketika dalam susasana yang prihatin, dapat beribadah lebih leluasa, dan dapat lebih tenang dalam memaknai kehidupan religiusitasnya serta siap dalam menjalani tugas kehidupan atau berfungsi secara sosial. Hasil dari pengabdian ini memperlihatkan adanya potensi yang tumbuh kembali setelah warga mulai tinggal di panti. Perubahan itu terlihat dengan adanya perubahan pada aspek-aspek kebermaknaan hidup mulai dari dimensi personal, dimensi sosial, dan dimensi nilai-nilai.
Recovery from ‘schizophrenia’: Perspectives of mental health nurses in the Eastern island of Indonesia
Authors: Tasijawa Fandro Armando , Suryani Suryani , Sutini Titin , Maelissa Sinthia Rosanti 
Published: August 2021

Background: Recovery is a way of life to make people’s lives more meaningful by working and interacting socially in the community. The recovery has become a new vision of mental health services, including in persons with schizophrenia. However, this concept is relatively new and still limited to nurses in developing countries, such as Indonesia. Several studies among nurses related to this topic have been conducted in the Western part of Indonesia. Yet, no studies have been implemented in the Eastern part of Indonesia. Therefore, exploring nurses’ perspectives in the Eastern island of Indonesia is necessary to provide a complete understanding of recovery in patients with schizophrenia.Objective: To explore the perspectives of mental health nurses on recovery from schizophrenia. Methods: This was a qualitative study using a phenomenological design. The study was conducted from April to May 2020 at community health centers in Maluku, Indonesia. Eight nurses recruited using purposive sampling participated in in-depth interviews. The interviews were audio-recorded, transcribed verbatim, validated, and analyzed based on Colaizzi’s method of data analysis.Results: Five themes were generated, including (i) treat a patient like a brother, (ii) recovery as an unfamiliar term with various meanings, (iii) medication as the primary action but also the main problem, (iv) being recovered if referred to a mental hospital, and (v) ineffective mental health programs.Conclusion: The findings of this study can be used as an input and evaluation for nurse managers to make an effort to uniform the perception among nurses in Indonesia regarding the recovery process in schizophrenia. It is also suggested that community health centers leaders and mental health policymakers prioritize and optimize recovery-oriented mental health programs and services in the Eastern island of Indonesia. Additionally, the findings offer new insight about ‘we are brothers’ or called ‘hidop orang basudara’, which is expected to be one motto for nursing care in Indonesia and beyond.
Study of lncRNA TPA in Promoting Invasion and Metastasis of Breast Cancer Mediated by TGF-β Signaling Pathway
Authors: Li Qinglin , Mo Wenju , Ding Yuqin , Ding Xiaowen 
Published: August 2021

PurposeThis study was to investigate the effects of lncRNA TPA overexpression and knockdown in stable transfected cell lines on the EMT, migration and invasion capabilities of breast cancer cells.MethodsWB and qRT-PCR were used to detect the expression of E-cadherin, Vimentin, fibronectin and N-cadherin, the key molecules of EMT, to determine whether lncRNA regulates EMT; scratch, migration and invasion assay were used to detected the effect of lncRNA TPA on the migration and invasion of breast cancer cells. The effect of lncRNA TPA on breast cancer metastasis was observed in nude mice model. Pierce Magnetic RNA-Protein Pull-Down Kit was used to bind the 3′-terminal desulfurized biotin-labeled lncRNA TPA with Magnetic beads, and then incubated with the proteins extracted from cell line C and D, respectively. After elution of the binding proteins, the interacting proteins were further identified by mass spectrometry to screen out the interacting proteins. The candidate proteins were expressed and purified in vitro, and the interaction between lncRNA-candidate proteins were verified by RNA-EMSA.ResultsOverexpression of lncRNA TPA decreased the expression of E-cadherin, and significantly increased the expression of Vimentin, fibronectin and TGF-β1 (p &lt; 0.01), and increased the migration rate, migration ability and invasion ability of cell group (P &lt; 0.01). Multiple lung metastases were observed in the lung tissue of nude mice with overexpression of lncRNA TPA.ConclusionLncRNA TPA affects the occurrence of breast cancer EMT through TGF-β signaling pathway, and then promotes the invasion and metastasis of breast cancer. LncRNA TPA may affect the corresponding signaling pathways through one or more interacting proteins, and ultimately promote the invasion and metastasis of breast cancer.
Older Adults Engage With Personalized Digital Coaching Programs at Rates That Exceed Those of Younger Adults
Authors: Graham Sarah A. , Stein Natalie , Shemaj Fjori , Branch OraLee H. , Paruthi Jason , Kanick Stephen Chad 
Published: August 2021

Background: The US population is aging and has an expanding set of healthcare needs for the prevention and management of chronic conditions. Older adults contribute disproportionately to US healthcare costs, accounting for 34% of total healthcare expenditures in 2014 but only 15% of the population. Fully automated, digital health programs offer a scalable and cost-effective option to help manage chronic conditions. However, the literature on technology use suggests that older adults face barriers to the use of digital technologies that could limit their engagement with digital health programs. The objective of this study was to characterize the engagement of adults 65 years and older with a fully automated digital health platform called Lark Health and compare their engagement to that of adults aged 35–64 years.Methods: We analyzed data from 2,169 Lark platform users across four different coaching programs (diabetes prevention, diabetes care, hypertension care, and prevention) over a 12-month period. We characterized user engagement as participation in digital coaching conversations, meals logged, and device measurements. We compared engagement metrics between older and younger adults using nonparametric bivariate analyses.Main Results: Aggregate engagement across all users during the 12-month period included 1,623,178 coaching conversations, 588,436 meals logged, and 203,693 device measurements. We found that older adults were significantly more engaged with the digital platform than younger adults, evidenced by older adults participating in a larger median number of coaching conversations (514 vs. 428) and logging more meals (174 vs. 89) and device measurements (39 vs. 28) all p ≤ 0.01.Conclusions: Older adult users of a commercially available, fully digital health platform exhibited greater engagement than younger adults. These findings suggest that despite potential barriers, older adults readily adopted digital health technologies. Fully digital health programs may present a widely scalable and cost-effective alternative to traditional telehealth models that still require costly touchpoints with human care providers.
Anodic Performance of BaO-Added Ni/SDC for Solid Oxide Fuel Cell Fed With Dry CH4
Authors: Itagaki Yoshiteru , Yamaguchi Syuhei , Yahiro Hidenori 
Published: August 2021

SOFCs fed with dry H2 and CH4 fuels were examined using 20 wt% Ni/SDC and 0.2 wt% BaO-added 20 wt% Ni/SDC [Ni(BaO)/SDC] anodes. The i–v characteristics of the cells in H2 and CH4 resulted in a higher output produced by CH4 fuel compared to that produced by H2 fuel in both anodes. In both fuels, better anode characteristics were obtained for Ni(BaO)/SDC. Consequently, the anodic performance was in the order of Ni(BaO)/SDC in CH4 &gt; Ni/SDC in CH4 &gt; Ni(BaO)/SDC in H2 &gt; Ni/SDC in H2. A significant carbon deposition was observed in the Ni/SDC anode in CH4, but the carbon deposition observed in Ni(BaO)/SDC was less. From the DC electrical resistance measurement of the anode films, a remarkable decrease in resistance was observed in Ni/SDC due to the carbon deposition after CH4 exposure. The resistance of Ni(BaO)/SDC was higher than that of Ni/SDC and did not change even after CH4 exposure because of the less carbon deposit. The high dispersibility of Ni particles was confirmed in both anodes and was particularly remarkable in Ni(BaO)/SDC. The highest anodic performance in Ni(BaO)/SDC was attributed to the high Ni dispersibility which might promote CH4 decomposition by producing less carbon deposit. It was speculated that the higher cell output in CH4 than that in H2 is due to the locally high concentration of H2 and/or CO gas on the anode surface by the promotion of CH4 decomposition.
Factors Associated With the Use of the Contraceptive Implant Among Women Attending a Primary Health Clinic in Cape Town, South Africa
Authors: Jonas Kim , Mazinu Mikateko , Kalichman Moira , Kalichman Seth , Lombard Carl , Morroni Chelsea , Mathews Catherine 
Published: August 2021

Background:Long-acting reversible contraceptives (LARCs), which include the subdermal contraceptive implant and intrauterine contraception, offer women safe, highly effective, long-term pregnancy prevention, and have expanded contraceptive options. The implant greatly expands LARC options for South African women as it is available free of charge at public health facilities, but little is known about factors associated with its uptake. This study describes factors associated with the intention to use the implant, including knowledge and beliefs about the implant and perceived outcome expectancies of implant use among women in Cape Town, South Africa.Methods:Between 2015 and 2016, the authors conducted a quantitative, cross-sectional survey among adult women attending a public, primary health clinic in Cape Town, South Africa. Using a structured questionnaire, they measured knowledge, awareness, and attitudes, perceived outcome expectancy, and the intention to use the contraceptive implant in future among the women.Results:The authors surveyed 481 women (mean age 29.1 years). Most of the participants (n= 364, 75.6%) had heard about the implant, 45 (9.4%) were currently using it, and 97 (20.2%) intended to use it in the future. Knowledge about the safety of the implant, beliefs about its effectiveness, and the ease of insertion and removal, and support from intimate partners were positively associated with the current use and intentions to use the implant in the future.Conclusions:Limited knowledge of the implant, having completed secondary schooling, support from partner for women to use implant and the perceived outcome expectancies of using the implant were factors significantly associated with the intention to use the implant. Ensuring that the contraception information is available in all South African languages, regardless of education levels in women, and that comprehensive contraception education and counseling is provided during all family planning might help improve the uptake of contraceptives, including the use of the implant in the country.
Different Effects of Mg and Si Doping on the Thermal Transport of Gallium Nitride
Authors: Li Shaoxun , Yu Linfeng , Qi Chengdong , Du Kun , Qin Guangzhao , Xiong Zhihua 
Published: August 2021

Mg and Si as the typical dopants for p- and n-type gallium nitride (GaN), respectively, are widely used in GaN-based photoelectric devices. The thermal transport properties play a key role in the thermal stability and lifetime of photoelectric devices, which are of significant urgency to be studied, especially for the Mg- and Si-doped GaN. In this paper, the thermal conductivities of Mg- and Si-doped GaN were investigated based on first-principles calculations and phonon Boltzmann transport equation. The thermal conductivities of Mg-doped GaN are found to be 5.11 and 4.77 W/mK for in-plane and cross-plane directions, respectively. While for the Si-doped GaN, the thermal conductivity reaches the smaller value, which are 0.41 and 0.51 W/mK for in-plane and cross-plane directions, respectively. The decrease in thermal conductivity of Mg-doped GaN is attributed to the combined effect of low group velocities of optical phonon branches and small phonon relaxation time. In contrast, the sharp decrease of the thermal conductivity of Si-doped GaN is mainly attributed to the extremely small phonon relaxation time. Besides, the contribution of acoustic and optical phonon modes to the thermal conductivity has changed after GaN being doped with Mg and Si. Further analysis from the orbital projected electronic density of states and the electron localization function indicates that the strong polarization of Mg-N and Si-N bonds and the distortion of the local structures together lead to the low thermal conductivity. Our results would provide important information for the thermal management of GaN-based photoelectric devices.
A Case for the Non-Neurologist Telestroke Provider
Authors: Choi Justin , Petrone Ashley , Adcock Amelia 
Published: August 2021

Introduction: Telestroke networks have effectively increased the number of ischemic stroke patients who have access to acute stroke therapy. However, the availability of a dedicated group of stroke subspecialists is not always feasible. We hypothesize that rates of tPA recommendation, sensitivity of final diagnosis, and post-tPA hemorrhagic complications do not differ significantly between neurologists and an emergency-medicine physician during telestroke consultations.Methods: Retrospective review of all telestroke consults performed at a comprehensive stroke center over 1 year. Statistical analysis: Chi squared test.Results: Three hundred and three consults were performed among 6 spoke sites. 16% (48/303) were completed by the emergency medicine physician; 25% (76/303) were performed by non-stroke-trained neurologists, and 59% (179/303) were completed by a board-certified Vascular Neurologist. Overall rate of tPA recommendation was 40% (104/255), 38% (18/48), 41% (73/179), and 41% (31/76) among the all neurology-trained, emergency medicine-trained, stroke neurology-trained and other neurology- trained provider groups, respectively (p = 0.427). Sensitivity of final stroke diagnosis was 77% (14/18) and 72% (75/104) in the emergency-medicine trained and neurology-trained provider groups (p = 0.777) No symptomatic hemorrhagic complications following the administration of tPA via telestroke consultation occurred in any group over this time period. One asymptomatic intracerebral hemorrhage was observed (0.96% or 1/104) in the neurology-trained provider group.Discussion/Conclusion: Our results did not illustrate any statistically significant difference between care provided by an emergency medicine-trained physician and neurologists during telestroke consultation. While our study is limited by its relatively low numbers, it suggests that identifying a non-neurologist provider who has requisite clinical experience with acute stroke patients can safely and appropriately provide telestroke consultation. The lack of formerly trained neurologists, therefore, may not need to serve as an impediment to building an effective telestroke network. Future efforts should be focused on illuminating all strategies that facilitate sustainable telestroke implementation.
A Scientometric Visualization Analysis for Natural Products on Cancer Research from 2008 to 2020
Authors: Chen Haitao , Li Rongrong , Zhang Fan , Yao Qinghua , Guo Yong 
Published: August 2021

Background: An increasing number of studies have shown that natural products have anti-tumor effects, and it has become a hotspot in cancer research. However, few bibliometric analyses have been examined in this field systematically. The current study aimed to explore the status and provide the developing trends in the natural products on cancer research.Methods: Publications on natural products in cancer research were extracted from the Web of Science core collection database. CiteSpace (5.6.R3) software and GraphPad prism 6 were used to analyze and plot the references.Results: On February 1, 2021, 34,611 records of natural products in cancer research published from 2008 to 2020 were collected. The United States was the driving force, with a strong academic reputation in this area. The top-contributing institution was the Chinese Academy of Sciences. Most publications were published in Molecules. Efferth Thomas was the most prolific author, while Newman DJ was the most cited and frequently co-cited author. Flavonoid, curcumin, and polyphenol were the most widely studied natural products. Oleanolic acid and rosmarinic acid have gradually become research hotspots recently. Breast cancer, prostate cancer, and colorectal cancer were the most common types of cancer in this field. “Natural killer cell” was the leading research hotspot. The keywords of “leaf extract,” “molecular docking” and “gold nanoparticle” appeared most recently as research frontiers.Conclusion: Our results provided a general overview of the major research directions of natural products research in cancer. The mechanisms of natural products, especially those related to molecular docking, gold nanoparticle, gut microbiota, and immune checkpoints may soon become hotspots and should be closely monitored.
Effect of Eccentric Calcification of an Aortic Valve on the Implant Depth of a Venus-A Prosthesis During Transcatheter Aortic Valve Replacement: A Retrospective Study
Authors: Li Lanlan , Liu Yang , Jin Ping , Tang Jiayou , Lu Linhe , Zhu Guangyu , Xu Chennian , Ma Yanyan , Yang Jian 
Published: August 2021

ObjectOur goal was to assess the implant depth of a Venus-A prosthesis during transcatheter aortic valve replacement (TAVR) when the areas of eccentric calcification were distributed in different sections of the aortic valve.MethodsA total of 53 patients with eccentric calcification of the aortic valve who underwent TAVR with a Venus-A prosthesis from January 2018 to November 2019 were retrospectively analyzed. The patients were divided into three groups (A, B, and C) according to the location of the eccentric calcification, which was determined by preprocedural computerized tomography angiography (CTA) images. The prosthesis release process and position were evaluated by contrast aortography during TAVR, and the differences in valve implant depths were compared among the three groups. The effects of different aortic root structures and procedural strategies on prosthesis implant depth were analyzed.ResultsEleven patients had eccentric calcification in region A; 19 patients, in region B; and 23 patients, in region C. The patients with eccentric calcification in region B had a higher risk of prosthesis migration (10.5% upward and 21.1% downward), and the position of the prosthesis after TAVR in group B was the deepest among the three groups. When eccentric calcification was located in region A or C, the prosthesis was released at the standard position with more stability, and the location of the prosthesis was less deep after TAVR (region A: 4.12 ± 3.4 mm; region B: 10.2 ± 5.3 mm; region C: 8.4 ± 4.0 mm; region A vs. region B,P= 0.0004; region C vs. region B; andP= 0.0360). In addition, the left ventricular outflow tract (LVOT) (P= 0.0213) and aortic root angulation (P= 0.0263) also had a significant effect on implant depth in the aortic root structure of the patients. The prosthesis size was 28.3 ± 2.4 in the deep implant group and 26.4 ± 2.0 in the appropriate implant group (P= 0.0068).ConclusionThe implant depth of the Venus-A prosthesis is closely related to the distribution of eccentric calcification in the aortic valve during TAVR. Surgeons should adjust the surgical strategy according to aortic root morphology to prevent prosthesis migration.
Screen Time and Autism: Current Situation and Risk Factors for Screen Time Among Pre-school Children With ASD
Authors: Dong Han-Yu , Feng Jun-Yan , Wang Bing , Shan Ling , Jia Fei-Yong 
Published: August 2021

Objective: To investigate the current status of screen time in children with ASD, its correlation with autistic symptoms and developmental quotient (DQ), and the factors affecting screen time.Method: One hundred ninety-three Chinese children with ASD were recruited. We collected the demographic and screen time data using a questionnaire. The ASD core symptoms and developmental quotient (DQ) were measured by the Autism Behavior Checklist (ABC), Childhood Autism Rating Scale (CARS), Autism Diagnostic Observation Schedule-Second Edition (ADOS-2), Griffiths Development Scales-Chinese Language Edition (GDS-C), and Chinese Children's Parent-Child Relationship Questionnaire (CPCIS). Then, we analyzed the correlations between the screen time of children with ASD and the ABC, CARS, ADOS, GDS-C DQs, and CPCIS scores. Linear regression was used to analyze the risk factors that affect screen time.Results: The children's average daily screen time was 2.64 ± 2.24 h. Forty eight percent children were exposed to two or more types of electronic devices. Their favorite activity of screen time was watching cartoons. Only 34% children spent screen time accompanied by parents and with communication. 50.26% children had no screen time before sleeping. The screen time of children with ASD had a negative correlation with the GDS-C CQ (r = −0.234, P = 0.001) and the CPCIS score (r = −0.180, P = 0.012) and a positive correlation with the CARS score (r = 0.192, P = 0.009). A low father's education level (P = 0.010), less restriction of the child's screen time by the guardian (P = 0.001), greater caregiver screen time (P &lt; 0.001), the use of the screen as a tool for child rearing (P = 0.001), and the child's ownership of independent electronic equipment (P = 0.027) are risk factors for long screen time in children with ASD.Conclusion: The screen time of children with ASD in China is higher than the recommended standard, and the current situation is serious. The screen time of ASD children is related to their autism symptoms, DQ and parent-child interaction. Low paternal education levels, less restriction of children's screen time by guardians, greater guardian screen time, the use of screens in child rearing, and children's ownership of independent electronic equipment can lead to an increase in children's screen time. These findings may have implications for family intervention strategies.