bluuebunny/crossref_metadata_2025_split huggingface dataset:
Activated biochar derived from spentAuricularia auriculasubstrate for the efficient adsorption of cationic azo dyes from single and binary adsorptive systems
Authors: Su Long , Zhang Haibo , Oh Kokyo , Liu Na , Luo Yuan , Cheng Hongyan , Zhang Guosheng , He Xiaofang 
Published: June 2021

AbstractIn this study, spent Auricularia auricula substrate (AS)-derived biochar (ASBCs) and activated biochar with NaOH (A-ASBC) were evaluated for the adsorption of cationic azo dyes, including methylene blue (MB), rhodamine B (RB), and crystal violet (CV), from single and binary adsorptive systems. A-ASBC showed a higher maximum adsorption capacity for these dyes (MB: 53.62 mg·g−1, RB: 32.33 mg·g−1, CV: 735.73 mg·g−1) than ASBCs in a single system because it had a greater specific surface area and more oxygen containing-functional groups on the surface. The adsorption process of the three dyes onto the adsorbents was in good agreement with the Freundlich adsorption isotherm and fit the pseudo-second-order kinetic model, which revealed sorbate polymolecular layer formation over the adsorbent surface and the involvement of chemisorption. The adsorption mechanism showed that the adsorption of three dyes on adsorbents could be postulated as a multistep process with extraordinary affinity-induced adsorption in terms of both physisorption and chemisorption. In the binary adsorptive system, the results showed that all MB, RB, and CV had antagonistic/competitive effects on each other's adsorption (QBinary/QSingle &lt; 1). Furthermore, a phytotoxic assay affirmed the effectiveness of the adsorbent in adsorbing dye species from aqueous solutions using Brassica pekinensis L. seeds as the model. Therefore, activated biochar prepared from AS can be used as a potentially economical and effective adsorbent for treating printing and dyeing wastewater.
The Functional Role of Oncogenic LncRNA BCAR4 for Cancer Outcome
Authors: Wang Bei , Xu Wen , Cai Yuxuan , Liu Kai , Wu Jiacheng , Guo Chong , Yuan Chengfu 
Published: June 2021

Background:
Long non-coding RNA (lncRNA) breast cancer anti-estrogen resistance 4 (BCAR4) is
a characterized oncogenic lncRNA in different cancers. This review is dedicated to summarize various molecular
mechanisms of BCAR4 and demonstrate that the biological functions exerted by BCAR4 are good entry
points for therapy.

Methods:
The molecular mechanism of BCAR4 acting on tumors is summarized by reviewing PubMed.

Results:
The expression of lncRNA BCAR4 is abnormally increased in all kinds of tumors, including colorectal
cancer, prostate cancer, bladder cancer, gastric cancer, chondrosarcoma, glioma, breast cancer, glioma, gastric
cancer, liver cancer, cervical cancer, lung cancer, etc. Besides, BCAR4 mediates multiple processes involved
in carcinogenesis, including proliferation, invasion, anti-apoptosis, migration.

Conclusion:
BCAR4 may show great clinical value in this direction as a therapeutic cancer target.
Liver Transplantation in Children: An Overview of Organ Allocation and Surgical Management
Authors: Grimaldi Chiara , Spada Marco , Maggiore Giuseppe 
Published: June 2021

:
Liver transplantation is the standard treatment for children with end-stage liver disease,
primary hepatic neoplasms, or liver-localized metabolic defects. Perioperative mortality is almost
absent, and long-term survival exceeds 90%. Organ shortage is managed thanks to advances in organ
retrieval techniques; living donation and partial liver transplantation almost eliminated waiting
list mortality, thus leading to expanding indications for transplantation. The success of pediatric liver
transplantation depends on the prompt and early referral of patients to transplant Centers and on
the close and integrated multidisciplinary collaboration between pediatricians, hepatologists, surgeons,
intensivists, oncologists, pathologists, coordinating nurses, psychologists, and social workers.
Evaluation of Heat Distribution for the Diagnosis of the Hoof with Abscess by Infrared Thermography in Horses
Authors: Kim Su-Min , Cho Gil-Jae 
Published: June 2021

Background:
The study of normal temperature distribution for the diagnosis of hoof disease in horses using Infrared Thermography (IRT) is rare, therefore, the normal temperature distribution is to be investigated. In this study, we investigated the possible use of IRT in the diagnosis of hoof disease in horses.

Methods:
A total of 66 horses (56 healthy horses and 10 horses with hoof abscess) were used in this study. Veterinarians and farriers performed physical examinations, such as lameness examination, palpation, hoof test, and radiography, on all horses. IRT was performed in standard conditions. The plantar of the hoof was lifted upward by the owner, and the distance of the thermal camera between the plantar of the hoof was 0.3 - 0.5 m. For evaluation, the heat pattern of the plantar of the hoof was divided into seven regions of interest (ROIs), and statistical analysis was performed.

Results:
On performing IRT, the temperature of healthy hooves and hooves with hoof abscess was found to be 25.77 °C ± 3.87 °C (mean ± SD) and 31.94 °C ± 2.60 °C, respectively (p < 0.0001). The mean temperature of ROIs in hooves with abscesses was 6.17 °C higher than that of healthy hooves. Sole regions were found to be especially prominent. Additionally, all ROIs of hooves with hoof abscess classified IRT with high sensitivity (74.3%) and specificity (87.5%).

Conclusion:
The present study demonstrated the usefulness of IRT in diagnosing hoof with abscess. Moreover, this study suggests that IRT may be useful as a new temperature measurement analysis system in terms of determining differences in the heat distribution of the hoof.
Plasma Fibrinogen as a Biomarker of Stable and Exacerbated Chronic Obstructive Pulmonary Disease
Authors: Ehsan Kashifa , Zulfiqar Sibgha , Hassan Amber , Waseem Humaira 
Published: June 2021

Study Design:
An experimental, comparative, cross-sectional study

Place and Duration of Study:
Department of Physiology, Federal Post Graduate Medical Institute (FPGMI), Sheikh Zayed Medical Complex Lahore, Pakistan from August 2013 to 2014

Background:
Chronic Obstructive Pulmonary Disease (COPD) is a preventable and treatable disease, but is a partially reversible chronic inflammatory condition characterized by airway obstruction. COPD remains under-diagnosed and under-treated because the only available diagnostic method at present is testing lung functions by spirometry which is not helpful to determine the severity and clinical outcomes of the disease. Circulating biomarkers are under consideration for various diseases worldwide. Plasma fibrinogen is emerging as one of the most promising biomarkers of COPD in smokers.

Objective:

The objective of this study is to investigate if plasma fibrinogen can serve as a diagnostic biomarker of COPD in smokers, and if its further higher levels are seen in the exacerbated state of the disease in comparison to the stable disease.

Materials and Methods:
75 middle-aged to old-age smokers of either gender were selected. Lung functions of every participant were measured to determine Forced Expiratory Volume in the first second (FEV1), Forced Vital Capacity (FVC), and the ratio of FEV1/FVC by spirometry. On the basis of the results of the tests, subjects were divided into three groups; firstly, the control group of chronic smokers without COPD, secondly, smokers with COPD in a stable state, and thirdly, patients in an exacerbated state of COPD. Plasma fibrinogen was quantitatively estimated in every individual of all three groups by the Clauss method using the Hemostat Fibrinogen kit.

Results:
The average Plasma fibrinogen level was found to be 235.008 mg/dl in healthy smokers (control group), while an average of 440.12mg/dl was measured in patients with stable COPD. The difference in plasma fibrinogen levels was found to be significant, having a p-value of (0.000). In the third group with declined lung function predicting acute exacerbated COPD, fibrinogen was found to be > 453.2 mg/dl, which was significantly higher than in the stable disease group (p-value > 0.0017)

Conclusion:
Plasma fibrinogen level measurement is a reliable and accessible test in terms of a diagnostic marker of COPD, as compared to conventional lung function testing done in the past.
An Insight into the Dermatological Applications of Neem: A Review on Traditional and Modern Aspect
Authors: Singh Varinder , Roy Meghaditya , Garg Nidhi , Kumar Amit , Arora Sandeep , Malik Deepinder Singh 
Published: June 2021

Background :
Dermatological disorders are cutaneous infirmities
which are frequently occurring and increasing at an alarming rate. These range
from mild itching/redness (dermatitis) to fatal skin cancers and has posed a major
health concern. Azadirachta indica A. Juss (commonly known as neem), a
member of Meliaceae family, is an Indian medicinal plant which has been known
for its health promoting effects since ancient times.

Objective:
The review highlights the traditional practices, pharmacological aspects,
and formulatory approach of neem for the treatment of dermatological disorders.
Further, recent patents and novel delivery systems (developed and in pipeline)
improving skin delivery and therapeutic profile of neem are discussed.

Results :
Neem is a traditional medicinal plant that has been employed for the prevention
and treatment of numerous ailments covering systemic and topical disorders.
Scientific studies have validated the traditional claims of neem and attributed
these health benefits to the presence of more than 300 structurally diverse and
complex compounds. It possesses anti-inflammatory, antibacterial, analgesic, antiviral,
antifungal, immunomodulatory and antioxidant activities which substantiate
its use as skin therapy. Various novel formulations and associated patents that
improved the permeability of neem based products across skin could be found in
literature.

Conclusion :
Critical appraisal of available literature revealed that neem possesses
anti-microbial, anti-inflammatory, antioxidant and antiseptic properties. Thus
it has the potential to be developed as a single effective therapy for the management
of multimodal skin disorders. Further, pharmaceutical tailoring of neem by
implication of novel carriers could enhance its penetrability across skin.
Enabling Nurse-Patient Communication With a Mobile App: Controlled Pretest-Posttest Study With Nurses and Non–English-Speaking Patients
Authors: Silvera-Tawil David , Pocock Courtney , Bradford DanaKai , Donnell Andrea , Freyne Jill , Harrap Karen , Brinkmann Sally 
Published: June 2021

Background
There is growing concern regarding the implications of miscommunication in health care settings, the results of which can have serious detrimental impacts on patient safety and health outcomes. Effective communication between nurses and patients is integral in the delivery of timely, competent, and safe care. In a hospital environment where care is delivered 24 hours a day, interpreters are not always available. In 2014, we developed a communication app to support patients’ interactions with allied health clinicians when interpreters are not present. In 2017, we expanded this app to meet the needs of the nursing workforce. The app contains a fixed set of phrases translated into common languages, and communication is supported by text, images, audio content, and video content.

Objective
This study aims to evaluate the efficacy of the communication app to support nursing staff during the provision of standard care to patients from non–English-speaking backgrounds when an interpreter is not available.

Methods
This study used a one-group pretest-posttest sequential explanatory mixed methods research design, with quantitative data analyzed using inferential statistics and qualitative data analyzed via thematic content analysis. A total of 134 observation sessions (82 pretest and 52 posttest) of everyday nurse-patient interactions and 396 app use sessions were recorded. In addition, a total of 134 surveys (82 pretest and 52 posttest) with nursing staff, 7 interviews with patients, and 3 focus groups with a total of 9 nursing staff participants were held between January and November 2017.

Results
In the absence of the app, baseline interactions with patients from English-speaking backgrounds were rated as more successful (t80=5.69; P<.001) than interactions with patients from non–English-speaking backgrounds. When staff used the app during the live trial, interactions with patients from non–English-speaking backgrounds were rated as more successful than interactions without the app (F2,119=8.17; P<.001; η2=0.37). In addition, the level of staff frustration was rated lower when the app was used to communicate (t80=2.71; P=.008; r=0.29). Most participants indicated that the app assisted them in communicating.

Conclusions
Through the use of the app, a number of patients from non–English-speaking backgrounds experienced better provision of standard care, similar to their English-speaking peers. Thus, the app can be seen as contributing to the delivery of equitable health care.
Identification and Reporting of Patient and Public Partner Authorship on Knowledge Syntheses: Rapid Review
Authors: Ellis Ursula , Kitchin Vanessa , Vis-Dunbar Mathew 
Published: June 2021

Background
Patient and public involvement (PPI) in health research is an area of growing interest. Several studies have examined the use and impact of PPI in knowledge syntheses (systematic, scoping, and related reviews); however, few studies have focused specifically on the patient or public coauthorship of such reviews.

Objective
This study seeks to identify published systematic and scoping reviews coauthored by patient or public partners and examine the characteristics of these coauthored reviews, such as which journals publish them, geographic location of research teams, and terms used to describe patient or public partner authors in affiliations, abstracts, or article text.

Methods
We searched CAB Direct, CINAHL, Cochrane Database of Systematic Reviews (Ovid), Embase (Ovid), MEDLINE (Ovid), and PsycInfo from 2011 to May 2019, with a supplementary search of several PPI-focused databases. We refined the Ovid MEDLINE search by examining frequently used words and phrases in relevant search results and searched Ovid MEDLINE using the modified search strategy in June 2020.

Results
We screened 13,998 results and found 37 studies that met our inclusion criteria. In line with other PPI research, we found that a wide range of terms were used for patient and public authors in author affiliations. In some cases, partners were easy to identify with titles such as patient, caregiver or consumer representative, patient partner, expert by experience, citizen researcher, or public contributor. In 11% (n=4) of studies, they were identified as members of a panel or advisory council. In 27% (n=10) of articles, it was either impossible or difficult to tell whether an author was a partner solely from the affiliation, and confirmation was found elsewhere in the article. We also investigated where in the reviews the partner coauthors’ roles were described, and when possible, what their specific roles were. Often, there was little or no information about which review tasks the partner coauthors contributed to. Furthermore, only 14% (5/37) of reviews mentioned patient or public involvement as authors in the abstract; involvement was often only indicated in the author affiliation field or in the review text (most often in the methods or contributions section).

Conclusions
Our findings add to the evidence that searching for coproduced research is difficult because of the diversity of terms used to describe patient and public partners, and the lack of consistent, detailed reporting about PPI. For better discoverability, we recommend ensuring that patient and public authorships are indicated in commonly searched database fields. When patient and public-authored research is easier to find, its impact will be easier to measure.
Efectos secundarios de las terapias oncológicas en pacientes con cáncer de cérvix
Authors: Guzman-Rivera Jose Vladimir , Alvira-Guauña Diana Cristina 
Published: June 2021

Objetivo: Determinar los efectos adversos de las terapias oncológicas en pacientes con cáncer de cérvix en una unidad oncológica de Neiva Huila, durante el 2017. Metodología: Estudio observacional, retrospectivo, descriptivo de corte transversal, basado en la revisión de fuentes secundarias, como son las historias clínicas de las pacientes con cancer de cérvix que estuvieron en tratamiento oncológico y que desarrollaron efectos adversos a las terapias oncológicas. La muestra se conformó con 75 pacientes, la cual se obtuvo atraves de un muestreo no proba­bilístico por conveniencia, previo al cumplimiento de criterios de inclusión y exclusión definidos para el estudio. Se describen características clínicas, terapias oncológicas y efectos adversos agrupados por sistemas. Resultados: Durante el periodo de estudio, se identificaron 75 pacientes que desarrollaron efectos adversos atribuidos a las terapias oncológicas, la edad en promedio fue de 49 años. En el grupo de 35-54 años, se presentó el mayor número de los casos con un 53,3% (IC 95%: 42,1-64,1). La radioterapia concomitante con quimioterapéuticos ocupó el primer lugar entre las terapias oncológicas con mayores efectos adversos en el 63% (IC 95%: 51,3-72,7) de las pacientes. El sistema gastrointestinal presentó mayores efectos adversos en el 95% (IC 95%: 87,0-97,9) de los casos. Conclusiones: Durante las consultas de seguimiento a riesgos, se identificó que las pacientes manifestaron sensaciones molestas a nivel gastrointestinal como: náuseas, emesis y diarrea, dado que la mucosa intestinal es más susceptible a las alteraciones generadas por la radiación y los quimioterapéuticos, por el alto recambio celular presentado en estos órganos.
Comparison of bacterial communities in roots of selected trees with and without summer truffle (Tuber aestivum) ectomycorrhiza
Authors: Siebyła Marta , Szyp-Borowska Iwona 
Published: June 2021

Abstract
In this study, we examined the effect of the presence of mycorrhiza and ascomata of summer truffle (Tuber aestivum) on the bacterial composition of roots from small trees growing in selected sites of the Nida Basin. Qualitative DNA sequencing methods such as Sanger and next-generation sequencing (NGS) were used.
The Sanger method revealed different bacterial species compositions between the samples where summer truffle ascomata was recorded and control samples. Five genera of bacteria could be distinguished: Bacillus, Erwinia, Pseudomonas, Rahnella and Serratia, among which the most numerous were Pseudomonas (Gammmaproteobacteria class) at 32.9%. The results obtained by the NGS method also showed differences in species composition of the bacteria depending on the study sample. Seven genera of bacteria were distinguished: Rhizorhabdus, Methylotenera, Sphingomonas, Nitrosospira, Streptomyces, Methyloceanibacter and Niastella, which dominated in roots from the truffle sites. Telmatobacter, Roseiarcus, Granulicella, Paludibaculum, Acidipila, Acidisphaera and Aliidongia dominated in roots from the control sites. With the NGS method, it is possible to identify the microbiome of a whole root, while only a root fragment can be analysed by the Sanger method.
These results extend the scope of knowledge on the preferences of certain groups of bacteria associated with truffles and their influence on the formation of ascomata in summer truffles. Our results may also be useful in selecting and monitoring sites that promote ascomata of Tuber aestivum.
Illuminance under canopy in different types of forest in the northern taiga
Authors: Feklistov Pavel , Sobolev Alexandr , Barzut Oksana , Neverov Nikolay 
Published: June 2021

Abstract
The illumination under the canopy in different types of pine and spruce forests is considered. The research was carried out in different points of the Northern taiga of the Arkhangelsk region. Illumination was measured using a luxmeter in different directions: at the level of the moss-lichen layer, at the level of the grass-shrub layer and at a height of 1.3 m; at different distances from the tree trunk; at different distances from the edge of the forest.
Illumination in pine forests at the level of the moss-lichen layer is 2.3 times higher than in spruce forests. Under the canopy of spruce forests, it is 1–3%, and in the pine forests, 3–9% of the illumination in the open. Illumination from tree trunks to the edge increases in pine and spruce forests equally. The lowest illumination is observed at the level of the moss-lichen layer, then it increases to the grass-shrub layer, and then practically does not change. However, the difference between pine and spruce forests is consistently high 47%. The decrease in illumination in the tree stand as it moves away from the edge in blueberry pine forests is observed up to a distance of 10 m from the edge, and in blueberry spruce forests up to 6 m.
Alternatif Penegakan Hukum Pidana Melalui Musyawarah Mufakat dalam Sistem Peradilan Pidana Indonesia
Authors: Mahayuni I Gusti Ayu Made Yustina 
Published: June 2021

The practice of resolving criminal cases through consensus agreement has so far not yet been formally based, but the use of consensus agreement as an institution for resolving criminal cases has become part of dispute resolution in indigenous communities in Indonesia. Based on this background, the purpose of this study is to find out the practice to resolve criminal cases by means of consensus agreement to manifest justice, usefulness and legal certainty and to determine the limits of criminal cases that can be resolved through consensus agreement. This type of research is a normative legal research with a statutory approach and a concept approach. The analysis of legal material in this study was done descriptively, interpretatively, evaluatively and argumentatively. The results of the research show that the practice of resolving crimes through consensus to realize legal certainty, justice and usefulness needs to be done by combining the renewal of theories of development law and progressive law, also called integrative law, which is carried out based on values ??and moral ethics of Pancasila. Determination of the limitation of crime cases that can be resolved through consensus agreement, both general crime and special crime, is by determining the category or characteristics or classification of the crime case itself.
Praktik penyelesaian perkara tindak pidana melalui musyawarah mufakat selama ini memang belum ada landasan hukum formalnya, namun penggunaan musyawarah mufakat sebagai lembaga penyelesaian perkara pidana sudah menjadi bagian penyelesaian sengketa dalam masyarakat adat di Indonesia. Berdasarkan latar belakang tersebut tujuan penelitian ini untuk mengetahui praktik untuk menyelesaikan kasus kejahatan dengan cara musyawarah mufakat untuk memanifestasikan keadilan, kemanfaatan dan kepastian hukum dan penentuan batasan perkara tindak pidana yang dapat diselesaikan melalui musyawarah mufakat. Jenis penelitian yang digunakan merupakan penelitian hukum normatif dengan pendekatan perundang-undangan dan pendekatan konsep. Analisis bahan hukum dalam penelitian ini dilakukan secara deskriptif, interpretatif, evaluatif dan argumentatif analisis. Hasil penelitian menunjukkan praktik penyelesaian kejahatan melalui musyawarah mufakat untuk mewujudkan kepastian hukum, keadilan dan kemanfaatan perlu dilakukan dengan memadukan pembaharuan teori-teori hukum pembangunan serta hukum progresif disebut juga hukum integratif, yang dilaksanakan dengan didasari nilai dan etika moral Pancasila. Penentuan batasan perkara kejahatan yang bisa diselesaikan lewat musyawarah mufakat, baik kejahatan umum maupun kejahatan khusus, adalah dengan menentukan kategori atau karakteristik atau klasifikasi perkara tindak pidana itu sendiri.