bluuebunny/crossref_metadata_2025_split huggingface dataset:
Freight-Logistics-as-a-Service – Innovative Geschäftsmodelle für ein datengetriebenes Transportmanagement
Authors: Heinbach Christoph , Hagen Simon , Thomas Oliver 
Published: April 2021

ZusammenfassungDie Gestaltung digitaler Geschäftsmodelle basiert auf dem disruptiven Potenzial von technologischen Innovationen, das in unterschiedlichen Branchen genutzt wird. Der Logistik kommt in Anbetracht ihrer essentiellen Querschnittfunktion sowie der Entstehung umfangreicher Daten durch den Einsatz verschiedener IT-Systeme für die Abwicklung von Frachttransporten eine besondere Bedeutung zu. Derzeitige Debatten werden mit Blick auf das Cloud-Computing sowie die Merkmale neu entstehender digitaler Plattformen geführt. Insbesondere für das Transportmanagement im Güterkraftverkehr entstehen datenbasierte as-a-Service Konzepte, die das tradierte Geschäftsmodell von Logistikdienstleistern sowie das Geschäftsfeld der Anbieter von Transportmanagementsystemen (TMS) attackieren. Auffällig ist, dass einer prozessorientierten Betrachtung der cloudbasierten Anwendungssysteme bislang wenig Aufmerksamkeit entgegengebracht wurde. In diesem Beitrag soll ein vertieftes Verständnis für Fracht-Plattformen im Güterverkehr erzeugt werden. Anhand von Experteninterviews wird zunächst das Konzept Freight-Logistics-as-a-Service (FLaaS) für ein datengetriebenes Transportmanagement (DTM) entworfen. Im Anschluss werden auf Grundlage des Business Model Canvas die strategischen Betrachtungen der digitalen Plattformen um Aspekte der Geschäftsmodellentwicklung der Datendienstleister erweitert. Eine intelligente Nutzung des Datenpotentials zeigt sich insbesondere in der Verbesserung der Transparenz sowie der optimierten Auslastung der verfügbaren Transportressourcen. Durch das präsentierte Konzept FLaaS und das betrachtete cloudbasierte Geschäftsmodell werden abschließend strategische Handlungsmaßnahmen formuliert. Die Aspekte Datenkompetenz, Datenstrategie und Kollaboration sind für die Akteure von hoher Relevanz, um eine nachhaltige und wertschöpfende Gestaltung von datengetriebenen Transportketten zu erreichen.
Daten-Ökosysteme wider Willen: Herausforderungen des Pay-as-you-live-Geschäftsmodells im Kontext deutscher Krankenversicherungen
Authors: Wulf Nele , Betz Stefanie 
Published: April 2021

ZusammenfassungIn dem vorliegenden Beitrag wird der aktuelle Trend, Pay-as-you-live-Systeme (PAYL) in Verbindung mit Krankenversicherungen anzubieten, analysiert. PAYL-Systeme bedeutet konkret die kontinuierliche Erfassung von Gesundheitsdaten mithilfe technischer Geräte und Übermittlung dieser Daten an Versicherungen sowie die Auszahlung von Boni für erreichte Fitnessziele. Zunächst wird eine Definition von PAYL-Systemen dargelegt, dann werden die technischen Rahmenbedingungen erläutert, schließlich werden die Auswirkungen dieser sozio-technischen Systeme näher beleuchtet. Dies geschieht auf Grundlage unserer empirischen Untersuchung. Die drei identifizierten Hauptkonflikte betreffen die Genese von PAYL, seine Auswirkungen auf den Wert der Datensouveränität besonders für Versicherte und die Schwierigkeit, für den Anspruch auf Prävention und Kostenersparnis durch PAYL Evidenz zu erzeugen. Diese Konflikte werden diskutiert, um sowohl die direkten wie auch indirekten Auswirkungen der Digitalisierung und der Ökonomisierung des Sozialen durch PAYL zu beleuchten.
Early-phase scale-up of isoniazid preventive therapy for people living with HIV in two districts in Malawi (2017)
Authors: Nabity Scott A. , Gunde Laurence J. , Surie Diya , Shiraishi Ray W. , Kirking Hannah L. , Maida Alice , Auld Andrew F. , Odo Michael , Jahn Andreas , Nyirenda Rose K. , Oeltmann John E. 
Published: April 2021

Background
Isoniazid preventive therapy (IPT) against tuberculosis (TB) is a life-saving intervention for people living with HIV (PLHIV). In September 2017, Malawi began programmatic scale-up of IPT to eligible PLHIV in five districts with high HIV and TB burden. We measured the frequency and timeliness of early-phase IPT implementation to inform quality-improvement processes.

Methods and findings
We applied a two-stage cluster design with systematic, probability-proportional-to-size sampling of six U.S. Centers for Disease Control and Prevention (CDC)-affiliated antiretroviral therapy (ART) centers operating in the urban areas of Lilongwe and Blantyre, Malawi (November 2017). ART clinic patient volume determined cluster size. Within each cluster, we sequentially sampled approximately 50 PLHIV newly enrolled in ART care. We described a quality-of-care cascade for intensive TB case finding (ICF) and IPT in PLHIV. PLHIV newly enrolled in ART care were eligibility-screened for hepatitis and peripheral neuropathy, as well as for TB disease using a standardized four-symptom screening tool. Among eligible PLHIV, the overall weighted IPT initiation rate was 70% (95% CI: 46%–86%). Weighted IPT initiation among persons aged <15 years (30% [95% CI: 12%–55%]) was significantly lower than among persons aged ≥15 years (72% [95% CI: 47%–89%]; Rao-Scott chi-square P = 0.03). HIV-positive children aged <5 years had a weighted initiation rate of only 13% (95% CI: 1%–79%). For pregnant women, the weighted initiation rate was 67% (95% CI: 32%–90%), similar to non-pregnant women aged ≥15 years (72% [95% CI: 49%–87%]). Lastly, 95% (95% CI: 92%–97%) of eligible PLHIV started ART within one week of HIV diagnosis, and 92% (95% CI: 73%–98%) of patients receiving IPT began on the same day as ART.

Conclusions
Early-phase IPT uptake among adults at ART centers in Malawi was high. Child uptake needed improvement. National programs could adapt this framework to evaluate their ICF-IPT care cascades.
Controlled hypotension during neuraxial anesthesia is not associated with increased odds of in-hospital common severe medical complications in patients undergoing elective primary total hip arthroplasty – A retrospective case control study
Authors: Liu Jiabin , Zhong Haoyan , DeMeo Danya , Do Huong , Kirksey Meghan , Gonzalez Della Valle Alejandro , YaDeau Jacques 
Published: April 2021

IntroductionThe use of controlled hypotension during neuraxial anesthesia for joint arthroplasty is controversial. We conducted a large institutional database analysis to assess common in-hospital complications and mortality of patients undergoing primary total hip arthroplasty (THA) under controlled hypotension and neuraxial anesthesia.MethodsWe conducted a large retrospective case control study of 11,292 patients who underwent primary THA using neuraxial anesthesia between March 2016 and May 2019 in a single institution devoted to musculoskeletal care. The degree and duration of various mean arterial pressure (MAP) thresholds were analyzed for adjusted odds ratios with composite common severe complications (in-hospital myocardial infarction, stroke, and/or acute kidney injury) as the primary outcome.ResultsSixty-eight patients developed common severe complications (0.60%). Patients with complications were older (median age 75.6 vs 64.0 years) and had a higher American Society of Anesthesiologists (ASA) classification (45.6% vs 17.6% ASA III). The duration of hypotension at various MAP thresholds (45 to 70 mm Hg) was not associated with increasing odds of common severe medical complications.ConclusionsControlled hypotension (ranging from 45 to 70 mmHg) for a moderate duration during neuraxial anesthesia was not associated with increased odds of common severe complications (myocardial infarction, stroke, and/or acute kidney injury) among patients receiving neuraxial anesthesia for elective THA.
Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial
Authors: Zeigelboim Bianca Simone , José Maria Renata , Santos Geslaine Janaina Bueno dos , Severiano Maria Izabel Rodrigues , Teive Hélio Afonso Ghizoni , Stechman-Neto José , Santos Rosane Sampaio , de Araújo Cristiano Miranda , Cavalcante-Leão Bianca Lopes 
Published: April 2021

Background
Neurodegenerative diseases are sporadic hereditary conditions characterized by progressive dysfunction of the nervous system. Among the symptoms, vestibulopathy is one of the causes of discomfort and a decrease in quality of life. Hereditary spastic paraplegia is a heterogeneous group of hereditary degenerative diseases involving the disorder of a single gene and is characterized by the progressive retrograde degeneration of fibers in the spinal cord.

Objective
To determine the benefits of vestibular rehabilitation involving virtual reality by comparing pre intervention and post intervention assessments in individuals with hereditary spastic paraplegia.

Methods
In this randomized controlled clinical trial from the Rebec platform RBR-3jmx67 in which allocation concealment was performed and the evaluators be blinded will be included. The participants will include 40 patients diagnosed with hereditary spastic paraplegia. The interventions will include vestibular rehabilitation with virtual reality using the Wii® console, Wii-Remote and Wii Balance Board (Nintendo), and the studies will include pre- and post intervention assessments. Group I will include twenty volunteers who performed balance games. Group II will include twenty volunteers who performed balance games and muscle strength games. The games lasted from 30 minutes to an hour, and the sessions were performed twice a week for 10 weeks (total: 20 sessions).

Results
This study provides a definitive assessment of the effectiveness of a virtual reality vestibular rehabilitation program in halting the progression of hereditary spastic paraplegia, and this treatment can be personalized and affordable.

Conclusion
The study will determine whether a vestibular rehabilitation program with the Nintendo Wii® involving virtual reality can reduce the progressive effect of hereditary spastic paraplegia and serve as an alternative treatment option that is accessible and inexpensive.
Rebec platform trial: RBR-3JMX67.
Spatial variations and determinants of anemia among under-five children in Ethiopia, EDHS 2005–2016
Authors: Anteneh Zelalem Alamrew , Van Geertruyden Jean-Pierre 
Published: April 2021

Background
Anemia has severe public health significance in sub-Saharan Africa. In Ethiopia, anemia has been increasing in the last two decades, reaching the highest national level in 2016, however, the geospatial distribution and determinants of anemia in children weren’t well explored at a national level.

Methods
We used the Ethiopian Demographic and Health Survey(EDHS) data from 2005–2016. The data consists of samples of households (HHs) obtained through a two-stage stratified sampling procedure. Our analysis included 19,699 children. Descriptive statistics, geospatial analysis, and Generalized Linear Mixed Model (GLMMs) were used.

Results
The overall prevalence of anemia was 51.5%; the spatial distribution of anemia significantly different across clusters in each survey. Children from 6 to 11 months had higher odds of anemia compared to 24–59 months (Adjusted Odds ratio (AOR) = 3.4, 95%Confidence level (CI): 2.99–3.76). Children with the first and second birth order were less likely to be anemic compared to fifth and above (AOR = 0.60, 95%CI: 0.38–0.95, and AOR = 0.83, 95%C: 0.73–0.93) respectively. Mothers’ age 15 to 24 years was associated with higher odds of anemia compared to 35 to 49 years (AOR = 1.37, 95%CI: 1.20–1.55). Children from HHs with the poorest and poorer wealth category showed a higher odds of anemia compared to the richest (AOR = 1.67, 95%CI: 1.45–1.93, and AOR = 1.25, 95%CI: 1.08–1.45) respectively. Moreover, children from HHs with one to two under-five children were less likely to be anemic compared to those three and more (AOR = 0.83, 95%CI: 0.76–0.91).

Conclusions
The geospatial distribution of anemia among children varies in Ethiopia; it was highest in the East, Northeast, and Western regions of the country. Several factors were associated with anemia; therefore, interventions targeting the hotspots areas and specific determinant factors should be implemented by the concerned bodies to reduce the consequences of anemia on the generation.
Protocol: Prospective observational study investigating the prevalence and clinical outcome of portopulmonary hypertension in Japanese patients with chronic liver disease
Authors: Wakabayashi Shun-ichi , Joshita Satoru , Kimura Kazuhiro , Motoki Hirohiko , Kobayashi Hiroyuki , Yamashita Yuki , Sugiura Ayumi , Yamazaki Tomoo , Kuwahara Koichiro , Umemura Takeji 
Published: April 2021

BackgroundPortopulmonary hypertension (PoPH) is a subtype of the pulmonary arterial hypertension (PAH) associated with portal hypertension. There is a dissociation between the proportion of PoPH in PAH and that of PoPH in patients with liver cirrhosis, suggesting PoPH underdiagnosis and an incomplete understanding of this entity in the clinical setting. Specifically, real-world data in Japan is largely unknown as compared with in Europe and the United States. The present study aims to elucidate the prevalence and etiology of PoPH in Japanese patients with chronic liver disease.Methods and designIn this prospective, single-center, observational investigation of PoPH patients with chronic liver disease, a targeted 2,500 Japanese adult patients regularly visiting Shinshu University Hospital in Matsumoto, Japan, for chronic liver disease will complete a standardized questionnaire on the presence of PoPH symptoms. If the respondent has signs of possible PoPH, ultrasound echocardiography (UCG) will be performed as a primary screening. In the case that UCG findings indicate pulmonary hypertension, the patient will be referred to a cardiologist for further evaluation, whereby a definitive diagnosis PoPH can be made. PoPH prevalence and etiology will be investigated at the time of diagnosis. Afterwards, patients with PoPH will be followed for five years for determination of survival rate.DiscussionThis study will reveal the prevalence, etiology, and 5-year survival rate of PoPH in Japanese patients with chronic liver disease.Trial registrationThis study is being performed at Shinshu University following registration as UMIN 000042287 on October 29, 2020.
Prognostic factors of chronic pulmonary aspergillosis: A retrospective cohort of 264 patients from Japan
Authors: Kimura Yuya , Sasaki Yuka , Suzuki Junko , Suzuki Jun , Igei Hiroshi , Suzukawa Maho , Matsui Hirotoshi 
Published: April 2021

BackgroundChronic pulmonary aspergillosis (CPA) develops in various underlying pulmonary conditions. There is scarce data evaluating interstitial lung disease (ILD)/abnormalities (ILA) as such conditions, and it has not been explored much whether non-tuberculous mycobacterial pulmonary disease (NTM-PD) is a prognostic factor for mortality in CPA patients. Few reports had investigated prognostic factors of CPA including underlying pulmonary conditions.ObjectivesTo explore prognostic factors of CPA including pulmonary conditions.MethodsWe conducted a retrospective cohort study of 264 CPA patients from a center for pulmonary aspergillosis in Japan.ResultsSurvival rates were 78.7%, 61.0%, and 47.4% at 1, 3, and 5 years, respectively. Of 264 patients, 53 (20.1%) and 87 (33.1%) were complicated with ILA and NTM-PD. Several independent prognostic factors were identified by multivariate Cox proportional analysis: ILA (HR 1.76, 95%CI 1.06–2.92, p = 0.029), age (1.05, 1.02–1.08, p<0.001), male sex (2.48, 1.34–4.59, p = 0.004), body mass index of <18.5 kg/m2(1,87, 1.20–2.90, p = 0.005), presence of aspergilloma (1.59, 1.04–2.45, p = 0.033), and lower serum albumin (0.56, 0.38–0.83, p = 0.004). NTM-PD was not associated with higher mortality (0.85, 0.52–1.38, p = 0.51).ConclusionsThe poor prognosis of CPA and several prognostic factors were revealed. Early diagnosis and intervention is required with reference to such factors.
ÉTICA E PSICOLOGIA CONSIDERAÇÕES SOBRE A PESSOA NA PSICOTERAPIA
Authors: De Carvalho José Mauricio 
Published: April 2021

Neste trabalho, vamos apresentar as interdições éticas aos
procedimentos psicoterápicos. Nossa reflexão vai se concentrar
sobre a psicoterapia individual e terá por referencial teórico as
contribuições da fenomenologia para a compreensão da existência
humana.
OS EDITORIAIS DA REVISTA EDUCAÇÃO E FILOSOFIA DA UNIVERSIDADE FEDERAL DE UBERLÂNDIA: UMA PRIMEIRA ANaLISE
Authors: Loureiro Maria Dulcinea da Silva , Favacho André Marcio Picanço 
Published: April 2021

O presente artigo propõe-se a fazer uma reflexão sobre a Revista
Educação e Filosofia da Universidade Federal de Uberlândia, tendo
como objeto de análise os seus editoriais. Inicialmente,
descreveremos a trajetória da Revista em seus 17 anos de existência
e, para isso, faremos uma rápida incursão no seu ciclo de vida,
com o intuito de acompanhar as mudanças ocorridas, tanto no
seu aspecto técnico - referente Ã organização, publicação e
editoração da revista - quanto no conteúdo dos seus editoriais.
Em seguida, deter-nos-emos na análise dos editoriais, pois
compreendemos que os mesmos assumiram, durante muito tempo,
o papel de porta vozes dos inconformismos com a política social,
educacional, e com os encaminhamentos econômicos que estavam
sendo postos em prática com a política neoliberal.
É POSSaVEL ENSINAR O CERTO E O ERRADO?
Authors: Fenerich Claudia 
Published: April 2021

Este breve artigo procura encaminhar uma resposta
contemporânea à velha questão socrático-platônica sobre a
possibilidade de se ensinar a virtude. O problema é enfrentado sob
a perspectiva filosófica que confere à argumentação um papel
central com relação à moralidade. A partir dos pressupostos gerais
da teoria da argumentação, procede-se, então, estabelecendo-se
um confronto simultâneo entre essa perspectiva e as duas visões
filosóficas tradicionais, a essencialista e a relativista. Como aportes
teóricos principais, a título de exemplificação das tendências
consideradas, bem como dos embates histórico-filosóficos travados
entre elas, destacam-se aqui os pensamentos de Sócrates-Platão e
Perelman.
Application of system analysis and preventive maintenance on cigarette packer line
Authors: Karoui Mohamed fathi , Lakhoua Mohamed Najeh 
Published: April 2021

The use of system analysis and preventive maintenance in today’s industry becomes a necessity as it increases equipment availability. These methods reduce the frequency of failures. The objective of this article is to present a case study for improving the reliability and availability of a production group in an industrial enterprise. Next, we present an improvement in maintenance. Finally, we present and discuss the application of preventive maintenance. Through an industrial manufacturing model, we will combine three tools; SADT modelling, the FMECA analysis and the Pareto diagram to arrive at an optimal maintenance approach that will be a decision support tool in order to minimize the repair costs and the downtime of the system.
Evolution of research related to fruit and vegetable waste in agrifood supply chains: analysing past publications seeking to identify a path to future research
Authors: Guarnieri Patricia , Aguiar Raiane Costa Coimbra , Thome Karim Marini 
Published: April 2021

Population growth, coupled with a growing demand for food, and its consequent waste and economic, social, environmental, and nutritional impacts, has drawn attention to global discussions related to such issues. In this context, the objective of this research was to provide an overview of studies addressing food waste, in particular, fruits and vegetables. To achieve this purpose, a systematic literature review was carried out, covering papers published in international journals from 2007 to 2017, available in the Science Direct database. The results point out the best practices to avoid food waste, as mentioned in the literature considered. In addition, this study gathered information regarding the main characteristics of publications, such as the evolution of the number of publications per year; main methods and techniques used in research, and which journals excel at covering the theme. This paper may be useful to researchers and practitioners interested in this topic since it systematizes the knowledge related to food waste in fruit and vegetable supply chains.
Book Histories in the Digital Age: Challenges, Promises, Achievements
Authors: Rippl Gabriele , Lenker Ursula 
Published: April 2021

AbstractThis special issue ofAngliaaddresses the wide-ranging transformations digitization has created in the field of book history. Several decades after the birth of Digital Humanities, the contributors to this special issue take stock of the challenges, promises and achievements of digital editing and cataloguing of medieval manuscripts. In addition, the articles discuss and assess the potential of computational methods, of big data and algorithms, of text mining techniques, stylometrics, multi-dimensional scaling and clustering, together with navigational tools such as scatterplots and dendrograms. The objects of investigation are both medieval manuscripts and newly digitizedœuvresof modern writers such as Samuel Beckett, intermedial formats such as Alan Moore’s graphic novels and the online publication of a short story by Kristen Roupenian.
Habemus Corpora: Reapproaching Philological Problems in the Age of ‘Big’ Data
Authors: Faulkner Mark 
Published: April 2021

AbstractThis paper demonstrates the potential of new methodologies for using existing corpora of medieval English to better contextualise linguistic variants, a major task of philology and a key underpinning of our ability to answer major literary-historical questions, such as when, where and to what purpose medieval texts and manuscripts were produced. The primary focus of the article is the assistance these methods can offer in dating the composition of texts, which it illustrates with a case study of the “Old” English Life of St Neot, uniquely preserved in the mid-twelfth-century South-Eastern homiliary, London, British Library, Cotton Vespasian D.xiv, fols. 4–169. While the Life has recently been dated around 1100, examining its orthography, lexis, syntax and style alongside that of all other English-language texts surviving from before 1150 using new techniques for searching theDictionary of Old English Corpussuggests it is very unlikely to be this late. The article closes with some reflections on what book-historical research should prioritise as it further evolves into the digital age.
The Reader at Large: A Computational Approach to London, British Library, Cotton Caligula A.ii (Part One)
Authors: Edlich-Muth Miriam , Edlich-Muth Christian 
Published: April 2021

AbstractThis article draws on computational methods including multi-dimensional scaling and clustering to analyse the contents of the Middle English multi-text manuscript London, British Library, Cotton Caligula A.ii (Part One). It makes the argument that digital linguistic analysis can complement analogue scholarship on collections of this kind by providing new perspectives on the networks of intertextuality and thematic and linguistic resonance these groups of texts engender. In particular, it argues for the use of scatterplots and dendrograms as navigational tools in digital editions that create non-hierarchical frameworks within which readers can navigate the contents of multi-text manuscripts in flexible and self-directed ways.