bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Epidemiology of Plasmodium falciparum Malaria in the Bijagos Islands of Guinea-Bissau
Authors: McGregor David , Texeira da Silva Eunice , Grignard Lynn , Goncalves Adriana , Vasileva Hristina , Mabey David , Last Anna 
Published: March 2021

Abstract.Distribution of long-lasting insecticide-treated nets (LLINs), passive detection and treatment with artemisinin-based combination therapy (ACT), and intermittent preventive treatment in pregnancy (IPTp) are the mainstay malaria control measures of Guinea-Bissau’s national control programme. This study aimed to estimate the prevalence of Plasmodium falciparum on Bubaque, the most populous island of the country’s remote Bijagos archipelago. A cross-sectional survey was performed at the start of the rainy season in August 2017. Participants were recruited using systematic random sampling in a two-stage stratified cluster design. Malaria parasitemia was detected using rapid diagnostic tests (RDTs) and quantitative PCR (qPCR). Data on housing, education, larval source management, socioeconomic status, anemia, and malaria preventive measures were collected. Multivariable logistic regression models were constructed to identify associations with P. falciparum infection. Four hundred four persons (aged 6 months–79 years, median 17 years) were enrolled in the study. The prevalence of P. falciparum parasitemia was 5.8% by RDT (95% CI: 3.55–9.33) and 16.9% by qPCR (95% CI: 13.09–21.71). The prevalence of anemia was 74.3% (95% CI: 69.04–78.85) as defined by the WHO criteria. All sampled houses were found to have open eaves; 99.5% of the surveyed population reported sleeping under a bednet (95% CI: 97.8–99.9). Although reported LLIN use is high, there remains an appreciable prevalence of malaria, suggesting that transmission is ongoing and further tools are required to reduce the burden of the disease.
Effects of Gamma Irradiation of Human Serum Samples from rVSVΔG-ZEBOV-GP (V920) Ebola Virus Vaccine Recipients on Plaque-Reduction Neutralization Assays
Authors: Grant-Klein Rebecca J. , Antonello Joseph , Nichols Rick , Dubey Sheri , Simon Jakub K. 
Published: March 2021

ABSTRACTGamma irradiation (GI) is included in the CDC guidance on inactivation procedures to render a group of select agents and toxins nonviable. The Ebola virus falls within this group because it potentially poses a severe threat to public health and safety. To evaluate the impact of GI at a target dose of 50 kGy on neutralizing antibody titers induced by the rVSVΔG-ZEBOV-GP vaccine (V920), we constructed a panel of 48 paired human serum samples (GI-treated versus non–GI-treated) from healthy participants selected from a phase 3 study of V920 (study V920-012; NCT02503202). Neutralizing antibody titers were determined using a validated plaque-reduction neutralization test. GI of sera from V920 recipients was associated with approximately 20% reduction in postvaccination neutralizing antibody titers. GI was not associated with any change in pre-vaccination neutralizing antibody titers.
A Bead-Based Assay for the Detection of Antibodies against Trichinella spp. Infection in Humans
Authors: Kahsay Ruth , Gómez-Morales Maria A. , Rivera Hilda N. , McAuliffe Isabel , Pozio Edoardo , Handali Sukwan 
Published: March 2021

ABSTRACTHuman trichinellosis can be diagnosed by a combination of medical history, clinical presentation, and laboratory findings, and through detection of anti–Trichinella IgG in the patient’s sera. ELISA using excretory–secretory (E/S) antigens of Trichinella spiralis larvae is currently the most used assay to detect Trichinella spp. antibodies. Bead-based assay can detect antibodies to multiple antigens concurrently; the ability to detect antibody to T. spiralis using a bead assay could be useful for diagnosis and surveillance. We developed and evaluated a bead assay to detect and quantify total IgG or IgG4 Trichinella spp. antibodies in human serum using T. spiralis E/S antigens. The sensitivity and specificity of the assay were determined using serum from 110 subjects with a confirmed diagnosis of trichinellosis, 140 subjects with confirmed infections with other tissue-dwelling parasites, 98 human serum samples from residents of the United States with no known history of parasitic infection, and nine human serum samples from residents of Egypt with negative microscopy for intestinal parasites. Sensitivity and specificity were 93.6% and 94.3% for total IgG and 89.2% and 99.2% for IgG4, respectively. Twelve percent of sera from patients with confirmed schistosomiasis reacted with the IgG Trichinella bead assay, as did 11% of sera from patients with neurocysticercosis. The Trichinella spp. bead assay to detect IgG total antibody responses has a similar performance as the Trichinella E/S ELISA. The Trichinella spp. bead assay shows promise as a method to detect trichinellosis with a possibility to be used in multiplex applications.
Mechanisms for improving the quality of education
Authors: Yashkova N. V. 
Published: March 2021

In modern conditions, there is a competitive struggle among educational institutions for applicants in the educational space. Success is achieved only by an educational institution that has its own brand, based on high-quality education and the demand for its graduates in the real sector of the economy. Can increase your competitiveness by improving the quality of the educational process. This is possible through regular improvement of the educational process, introduction of new pedagogical technologies, and improvement of teachers pedagogical skills.The main directionsfor improving the quality of the educational process are work in the audience and work in the outside audience with students, as well as the activation of their scientific activities. It is possible to improve the quality of education by increasing the interest of students in the profession they are learning, so they will have internal motivation for better mastering the material and activating their educational and scientific activities. But to do this, the teacher must use modern pedagogical techniques and constantly develop himself. The article is written on the basis of the author’s own pedagogical experience. The article systematizes the directions of quality assessment, which can be used both for the organization of mechanisms for internal and external assessment of the quality of the educational process. Examples of experience in organizing the educational process are given.
Legal regulation of the implementation of secondary vocational education programs in the context of the COVID-19 pandemic
Authors: Matveev V. Yu. 
Published: March 2021

The purpose of the study is to identify problems in the legal regulation of the activities of the secondary vocational education system in the context of the COVID-19 pandemic and to formulate proposals for their leveling. The subject of study is individual institutions of educational legislation in the field of secondary vocational education, the implementation of which is directly related to the activities of educational organizations in the context of countering the spread of COVID-19.The key issues of the use of e-learning and distance learning technologies, the provision of paid educational services in the changed conditions are considered; practical issues, as well as the positions on them of the federal executive authorities and judicial practice. The main problems associated with the legal regulation of the education system in a pandemic are presented.Conclusions are made about the inadmissibility of giving assignments during the holidays to students; that the use of e-learning and distance learning technologies does not change the form of education, while maintaining the volume of compulsory classes of a teacher with students; on situations of application of these technologies, requiring free provision of students with the necessary equipment; on the need to change the content of the contract for the provision of paid educational services, as well as on the inadmissibility of increasing its cost.
Corporate requirements and training of personnel for railway transport in the system of secondary vocational education
Authors: Odinokov A. S. 
Published: March 2021

The modern system of secondary vocational education must meet the requirements of practice-orientedness, take into account the requirements of employers to the level of development of general and professional competencies of employees in specific specialties, taking into account the specifics of the type of professional activity. The core of the national qualifications system is represented by professional standards developed jointly with leading companies in the Russian national economy. Actual expectations and needs of employers are guidelines for them educational system of secondary vocational education in the process of modernizing educational standards and programs. Russian Railways, as a natural monopoly, takes an active part in the development of industry education and training for railway transport. The content of requirements for middle-level employees, who make up more than a quarter of the company’s staff, in specific areas of training is reflected in corporate standards.A brief historical review confirms the conclusion about the practical orientation of secondary vocational education in the field of railway transport, the significant accumulated experience of industry vocational education, the active participation of the relevant department, and then Russian Railways, in its optimization. The growing demand of the company for middle-level employees, skilled workers and employees is matched by the growth in the number of graduates of secondary vocational education institutions.The results of a comparative analysis of the content of the provisions of the Federal State Educational Standard of secondary vocational education and local acts of JSC Russian Railways related to the educational and professional training of technicians in the field of communication in railway transport are presented. The purpose of the study is to determine the similarities and differences in the requirements of corporate and educational standards for the composition and level of development of professional competencies among employees of this specialty. The findings will make it possible to identify ways to optimize the FSES of secondary vocational education in relation to the results of educational training, taking into account the expectations of the employer.
ORAL GRAFT-VERSUS-HOST DISEASES
Authors: Correa Maria Elvira Pizzigatti , Eduardo Fernanda De Paula , Macedo Leandro Dorigan de , Bezinelli Leticia Melo , Santos Paulo Sérgio da Silva , Antunes Héliton Spindola 
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
SINUSOIDAL OBSTRUCTION SYNDROME (SOS)
Authors: Salvino Marco Aurelio , Passos Roselene , Assis Luiz Henrique de , Borges Natalia Maria , Hamerschlak Nelson 
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
HSCT FOR ACQUIRED BONE MARROW FAILURE SYNDROMES
Authors: Atta Elias Hallack , Darrigo Junior Luiz Guilherme , Bonfim Carmem , Scheinberg Phillip 
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
HSCT FOR MONOCLONAL GAMMOPATHIES: MULTIPLE MYELOMA AND AMYLOIDOSIS
Authors: Maiolino Angelo , Hallack Neto Abrahão Elias , Magalhães Roberto , Crusoé Edvan , Nunes Renata Ferreira Marques , Hungria Vânia Tietsche de Morais , Mendonça Roberia , Ikoma-Colturato Maura Rosane Valério 
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
HSCT FOR CHRONIC MYELOPROLIFERATIVE DISEASES
Authors: Funke Vaneuza Araújo Moreira , Colella Marcos Paulo , Macedo Antonio Vaz de , Teixeira Gustavo Machado , Ribeiro Andreza Alice Feitosa , Vigorito Afonso Celso 
Published: March 2021

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION
Analisis Kesulitan Belajar Peserta Didik Kelas II Pada Materi Penjumlahan dan Pengurangan
Authors: Rohani Rohani , Hadi Saputra Heri , Kholifatur Rosydah Awal Nur 
Published: March 2021

Penelitian ini bertujuan untuk mengidentifikasi kesulitan belajar peserta didik pada materi penjumlahan dan pengurangan di kelas II Sekolah Dasar. Jenis penelitian ini adalah penelitian kualitatif dengan menggunakan metode deskriptif. Penelitian ini dilaksanakan di Sekolah Dasar Negeri 1 Suradadi pada bulan November 2020 dengan subjek penelitian 24 peserta didik kelas II. Instrumen dalam penelitian ini adalah tes, wawancara dan dokumentasi. Teknik analisis data yang digunakan yaitu analisis data model Iteraktif Analysis Miles and Huberman yang terdiri dari reduksi, penyajian data dan penarikan kesimpulan. Hasil penelitian menujukkan 1) terdapat peserta didik yang mengalami kesulitan belajar pada materi penjumlahan dan pengurangan; 2) kesulitan yang dialami oleh peserta didik kelas II disebabkan oleh beberapa faktor yaitu malas dan masih ada peserta didik yang belum bisa membaca sehingga tidak memahami maksud soal; 3) kesulitan yang dialami oleh peserta didik kelas II disebabkan karena kurangnya memahami konsep penjumalahan dan pengurangan bersusun panjang; 4) kesulitan belajar peserta didik disebabkan karena peserta didik tidak memahami konsep penjumlahan dan pengurangan teknik simpan dan teknik meminjam. Saran-saran yang dapat diberikan berdasarkan hasil penelitian yang telah dilakukan yaitu, bahwa pendampingan proses belajar penjumlahan dan pengurangan sangat perlu dilakukan oleh guru/orang tua dan penyajian soal sebaiknya dilakukan secara bertahap.
Faktor yang Mempengaruhi Keaktifan Belajar Peserta Didik Kelas III SD
Authors: Farida Payon Feni , Andrian Dyka , Mardikarini Sasi 
Published: March 2021

Pembelajaran yang baik adalah pembelajaran yang dapat mengaktifkan peserta didik. Tujuan dari penelitian ini adalah untuk mengetahui apa saja faktor-faktor yang dapat memengaruhi keaktifan belajar peserta didik pada muatan IPA di kelas III Sekolah Dasar. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian kualitatif. Subjek penelitian dalam penelitian ini adalah guru kelas III dan kepala sekolah selaku pembina. Objek dari penelitian ini adalah peserta didik kelas III SDN Ngujung 2 Maospati. Teknik pengumpulan yang digunakan dalam penelitian ini adalah observasi dan wawancara. Teknik analisis data yang digunakan dalam penelitian ini adalah reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian ini berupa faktor-faktor internal yang memengaruhi keaktifan belajar peserta didik kelas III Sekolah Dasar terdiri dari faktor internal dan eksternal. Faktor- faktor internal yang memengaruhi keaktifan belajar yaitu faktor fisiologis berupa keadaan fisik (panca indra), faktor psikologis berupa perhatian, tanggapan, serta ingatan menjadi faktor pendukung keaktifan belajar peserta didik. Sedangkan keadaan jasmani menjadi faktor penghambat keaktifan belajar peserta didik. Faktor-faktor eksternal yang memengaruhi keaktifan belajar peserta didik kelas III adalah faktor nonsosial yaitu tempat dan fasilitas serta faktor sosial yaitu guru dan teman sebaya. Tempat, fasilitas, dan guru menjadi faktor pendukung keaktifan belajar peserta didik. Sedangkan teman sebaya menjadi faktor yang dapat mengganggu keaktifan belajar peserta didik.
Bahan Ajar Tematik Berbasis Kompetensi Peserta Didik di Abad 21
Authors: Hasna Prilia Afifah , Irianto Sony , Sriyanto Sriyanto 
Published: March 2021

Perkembangan abad 21 menuntut peserta didik untuk lebih aktif dalam berpikir dan memecahkan masalah. Oleh sebab itu, pelaksanaan pembelajaran perlu didukung adanya bahan ajar tematik yang dapat menumbuhkan kompetensi peserta didik di abad 21. Penelitian ini merupakan jenis penelitian pengembangan yang bertujuan untuk mengembangkan bahan ajar tematik berbasis kompetensi peserta didik abad 21 di Kelas V. Penelitian dan pengembangan ini mengacu pada langkah-langkah penelitian dan pengembangan dengan model 4D. Pengumpulan data pada penelitian ini yaitu menggunakan wawancara, analisis dokumen, dan angket yang disebarkan kepada ahli materi, bahasa, dan pembelajaran serta angket respon guru. Hasil penelitian dan pengembangan ini berupa bahan ajar tematik berbasis kompetensi peserta didik abad 21 di kelas V sekolah dasar yang berisi enam tahap kegiatan pembelajaran. Keenam tahapan tersebut yaitu yaitu:1) memprediksikan, 2) berdiskusi I, 3) menjelaskan I, 4) pengamatan, 5) berdiskusi II, 6) menjelaskan II. Bahan ajar tematik pada tahap pertama dinyatakan layak oleh ketiga validator dengan kategori “baik”. Pada tahap kedua bahan ajar tematik dinyatakan layak dengan kategori “sangat baik”. Menurut respon guru dengan kategori “sangat baik”. Dengan demikian bahan ajar tematik tersebut dinyatakan layak digunakan untuk meningkatkan kemampuan empat kompetensi peserta didik abad 21di sekolah dasar.
Review of Chitra Banerjee’s Arranged Marriage Stories
Authors: G Niranjana , G Bhuvaneswari 
Published: March 2021

Book Review:
Chitra Banerjee Divakaruni, ‘Arranged Marriage Stories’, Anchor, 1996, 320p, ISBN-13: 978-0385483506
Reviewed by Niranjana G, Research Scholar, VIT Chennai, Bhuvaneswari, Assistant Professor, VIT Chennai
Clinical Profile of Patients Undergoing Laparoscopic Hysterectomy
Authors: Kumar Raj , Saravanan Selvapriya , Subburaj Lakshmi 
Published: March 2021

ABSTRACTBackgroundLaparoscopic hysterectomy is a minimally invasive procedure with shorter operative time, decreased trauma, and less technical difficulty. However, the success of the procedure depends on various intrinsic and extrinsic factors. This study was done to evaluate the factors which influence the success of laparoscopic hysterectomy.Materials and methodsThis retrospective record-based cross-sectional study was carried out among 100 participants who underwent laparoscopic hysterectomy for various indications in our tertiary care hospital. The demographic and clinical profiles of these participants were recorded. Particulars related to the success of the surgery including duration of surgery and hospital stay, infections, and other complications were recorded.ResultsOur study showed that the duration of surgery and duration of hospital stay were significantly influenced by the parity. Multiparous women were more prone to longer duration of surgery and prolonged hospitalization. The observed difference was statistically significant (p< 0.05).ConclusionIt is essential to develop a scoring mechanism by which each case can be selected or rejected for laparoscopic hysterectomy considering various parameters. This may be carried out by further exploratory research on identifying the key factors which influence the success of the procedure.How to cite this articleSubburaj L, Saravanan S, Kumar R. Clinical Profile of Patients Undergoing Laparoscopic Hysterectomy. J South Asian Feder Obst Gynae 2020;12(5):277–280.
Medicamentos em contexto local indígena
Authors: Diehl Eliana Elisabeth , Almeida Ledson Kurtz de 
Published: March 2021

O estudo sobre medicamentos em contextos locais é uma importante estratégia para a compreensão de como estão inseridos em diferentes realidades, entre elas as indígenas. No Brasil, ainda são raras as pesquisas que identificam os medicamentos que fazem parte do cotidiano dos povos indígenas. Esse trabalho examina os medicamentos encontrados (a “farmácia caseira”) nas casas Xokleng de uma aldeia da Terra Indígena (TI) Ibirama-Laklãnõ e o contexto de circulação e uso dos mesmos. A pesquisa de campo envolveu a observação participante e a utilização de entrevistas e questionário, esse último aplicado em setembro de 2008 e fevereiro de 2009. Nessa TI (em torno de 2.000 habitantes), cada uma das sete aldeias existentes na ocasião da pesquisa contava com um posto de saúde (PS), com agentes indígenas de saúde e auxiliares/técnicos de enfermagem próprios; dois médicos e um dentista atuavam em todos os PS; uma enfermeira permanecia no Polo-Base, como coordenadora, e outra atendia nas aldeias. Em 40 casas (95% do total) de uma das aldeias, foram identificados 456 medicamentos, sendo 21% genéricos. Segundo a classificação Anatômica Terapêutica e Química, destacaram-se os antieméticos, os analgésicos e antipiréticos, os anti-inflamatórios e antirreumáticos não esteroidais e os antibacterianos. Os comprimidos, as soluções orais em gotas, os xaropes e as pomadas se distinguiram entre as formas farmacêuticas. Os medicamentos foram prescritos pelo médico do PS e por outros médicos, entre outros profissionais de saúde, tendo sido ainda obtidos por automedicação. A aquisição dos medicamentos foi majoritariamente no PS da aldeia ou no Polo- base. Os dados indicam uma forte medicalização desse grupo indígena, estimulada por uma atenção à saúde caracterizada pelo assistencialismo hipermedicalizante, de caráter curativo. Além disso, osetor saúde ignora que a práxis dos usuários indígenas de como e quando usar os medicamentos é orientada pelos conhecimentos locais, experiência da doença e por conflitos de poder que intervêm o acesso e distribuição de medicamentos.
EVENTO QUEDAS: CUIDADOS DE ENFERMAGEM PARA A SEGURANÇA DO IDOSO HOSPITALIZADO
Authors: Carvalho Anderson Abreu de , Locks Melissa Orlandi Honório , Santos Silvia Azevedo dos , Alvarez Angela Maria , Schier Jordelina Schier , Fernandez Darla Lusia Ropelato , Soares Gustavo Lopes , Hammerschmidt Karina Silveira de Almeida 
Published: March 2021

Introdução: O processo de envelhecer é influenciado por diversos fatores, entre eles as doenças crônicas e os eventos adversos onde se destaca o evento quedas. As quedas de pacientes internados estão entre os principais eventos a serem prevenidos nas instituições e são prioridades dentro do programa de segurança do paciente. Elas podem acarretar consequências graves aos pacientes, como traumas, fraturas, dependência e morte. Objetivo: Identificar os cuidados de enfermagem, quanto ao evento quedas, para a segurança de idosos internados nas unidades de internação de clínica médica. Método: Pesquisa qualitativa do tipo exploratório-descritivo, realizada no período de março a abril de 2018, em duas unidades de Clínica Médica de um hospital escola, com Enfermeiros. A coleta de dados deu-se através de entrevista semi-estruturada, sendo essas gravadas, transcritas e analisadas segundo análise Minayo. Pesquisa aprovada pelo número: 80907517.5.0000.012. Resultados: Participarem 15 Enfermeiros, 14 mulheres e um homem. Através das entrevistas identificaram-se três categorias: Medidas de prevenção para quedas, extrínsecas, intrínsecas e comportamentais (avaliação dos riscos de quedas, ferramentas, e medidas de prevenção); Cuidados de enfermagem aos idosos que tiveram episódios de quedas (cuidados imediatos e registros dos cuidados) e Notificação das quedas no ambiente hospitalar (realização, fluxo de encaminhamento, divulgação dos eventos e subnotificação). Conclusões: Foi possível concluir que os Enfermeiros conhecem os fatores de risco e implementam ações de prevenção para as quedas, entretanto não conhecem ou pouco utilizam ferramentas e protocolos que padronizem as ações e auxiliem nos cuidados diários ao idoso com risco de quedas.
De last tot een uitgave van geld of goed: verplichting en vorderingsrecht?
Authors: Brinkman R.E. 
Published: March 2021

De last tot een uitgave van geld of goed: verplichting en vorderingsrecht?
In dit artikel bespreekt de auteur de last tot uitgave van geld of van een goed, al dan niet ‘uit de nalatenschap’, aan een of meer personen ten laste van een of meer (of de gezamenlijke) erfgenamen. De keuze van de wetgever om een dergelijke last niet meer als schuld van de nalatenschap te beschouwen, en de daaruit voortvloeiende aanpassingsoperatie van de nodige bepalingen in Boek 4 BW, heeft soms tot onnauwkeurige, soms tot inconsistente en soms zelfs tot onjuiste resultaten geleid.