bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Affecting Cancer Prevention Behaviors and Cancer Screening in First-Degree Relatives of Breast and Colorectal Cancer Patients in Korea: A Cross-Sectional Study
Authors: Lee Yoonjung , Lee Kyunghwa , Kim Sanghee 
Published: September 2021

BackgroundFirst-degree relatives (FDRs) of cancer patients have a high risk of cancer due to a similar lifestyle and genetic predisposition. However, previous studies rarely examined the level of cancer prevention behaviors and screening and affecting factors in cancer patients’ FDRs.PurposeThis study aimed to describe the levels of cancer knowledge, attitudes toward cancer, cancer worry, perceived cancer risk, and cancer prevention behaviors and cancer screening in FDRs of breast and colorectal cancer patients. Moreover, it sought to identify factors affecting cancer prevention behavior and cancer screening.MethodsA cross-sectional, descriptive correlational design was used. The study enrolled 138 FDRs of breast and colorectal cancer patients. Participants completed self-administered questionnaires at a tertiary hospital in Seoul, Korea. Descriptive statistics, frequencies, chi-square test, independent t test, one-way analysis of variance (ANOVA), Pearson’s correlation, multiple regression, and logistic regression were performed for data analysis.ResultsThe levels of perceived cancer risk, cancer knowledge, attitude toward cancer, and cancer prevention behaviors were moderate, while the level of cancer worry was high. Ninety-two participants reported having undergone cancer screenings, but the types of screening were not associated with their family history. Age, gender, and attitude toward cancer affected cancer prevention behaviors. The cancer screening rate was higher in older participants, in women, and in patients’ FDRs with a longer cancer diagnosis.Implications for PracticeAttitude was the modifiable factor for cancer prevention behaviors. Nurse-led educational and counseling interventions should be developed to improve attitude toward cancer among FDRs of cancer patients.
Invitro Antimicrobial Activities of Mitracarpus scaber Against Some Common Bacteria of Aquatic Origin
Authors: Ajadi Abdullateef Abiodun , Emikpe Benjamin , Akeem Ahmed 
Published: September 2021

Some plants have been reported to be of medicinal values and reserve some antimicrobial properties. One of such plants is Mitracarpus scaber and its effect on bacterial growth is evaluated. The study aimed at evaluating the phytochemical analyses and antimicrobial potentials of Mitracarpus scaber against aquatic bacteria including Aeromonas, Bacillus, Vibrio and Staphylococcus Spp. Leaves of Mitracarpus scaber were collected, washed and air dried and phytochemical analysis and antimicrobial investigation of ethanolic and aqueous extracts of the leaves were carried out against a panel of bacteria isolated from diseased catfish from various farms. The phytoconstituents detected include saponins, tannins, flavonoids, tarpenoids, steroids, anthraquinones and alkaloids in both aqueous and ethanolic extracts. Both aqueous and ethanolic extracts of M. scaber showed varying degree of antibacterial activities but ethanolic extract showed a higher activity against the pathogens tested. The ethanolic extract had zones of inhibition similar to that of standard antibiotics (enrofloxacin) across all tested microbes. The lowest minimum inhibitory concentration of ethanolic extract of M. scaber was against Bacillus sp with 10mg/ml while the highest was 85mg/ml against Staphylococcus species. The results of the assays showed promising evidences that M. scaber is a potential antibacterial agent against aquatic microbes. However, further studies are recommended to fractionate its constituents and determine the in vitro and in vivo anti-microbial activities and the exact mechanism of action of the constituents.
Identifikasi Ancylostoma spp., dan Trichuris spp. pada Anjing Pemburu di Kenagarian Sungai Kamuyang, Kecamatan Lareh Sago Halaban, Limapuluh Kota, Sumatra Barat
Authors: Putri Ilviga Anggraini , Noor Prima Silvia , Zelpina Engki , Sujatmiko Sujatmiko 
Published: September 2021

Anjing (Canis familiaris) adalah hewan yang sangat dekat berinteraksi dengan manusia. Selain sebagai hewan kesayangan anjing juga sering dimanfaatkan sebagai hewan pemburu. Salah satu penyakit parasitik yang sering menjadi permasalahan pada anjing pemburu adalah penyakit cacingan yang disebabkan oleh nematoda saluran pencernaan (gastrointestinal nematodes) yaitu Ancylostoma spp. dan Trichuris spp. yang dapat menyebabkan ancylostomiasis dan trichuriasis. Tujuan penelitian ini adalah untuk mengetahui infeksi Ancylostoma spp. dan Trichuris spp. serta prevalensi pada anjing pemburu. Penelitian ini merupakan penelitian observasional yang dilakukan secara cross sectional. Sampel yang diambil sebanyak 50 feses anjing pemburu dan diperiksa menggunakan metode uji apung. Hasil penelitian ini menunjukkan, bahwa 31 sampel feses anjing pemburu positif terinfeksi oleh nematoda dengan prevalensi 62% yang terdiri dari Ancylostoma spp. 52%, Trichuris spp. 6% dan infeksi ganda (Ancylostoma spp. dan Trichuris spp) sebesar 2%.
Expanding Role of Technology in Rehabilitation After Lower-Extremity Joint Replacement
Authors: McKeon John F. , Alvarez Paul M. , Vajapey Anuhya S. , Sarac Nikolas , Spitzer Andrew I. , Vajapey Sravya P. 
Published: September 2021

Background:
The effectiveness of telehealth programs in the administration of rehabilitation and the monitoring of postoperative progress after joint replacement is not well studied. The purpose of the present study was to systematically review the currently available evidence on the use of smart-device technology and telehealth programs to guide and monitor postoperative rehabilitation following total joint arthroplasty and to assess their impact on outcomes following surgery.

Methods:
A literature search of the MEDLINE database was performed using keywords “mobile,” “app,” “telehealth,” “virtual,” “arthroplasty,” “outcomes,” “joint replacement,” “web based,” “telemedicine,” “TKA,” “THA,” “activity tracker,” “fitness tracker,” “monitor,” “rehab,” “online,” and “stepcounter” in all possible combinations. All English studies with a level of evidence of I to III that were published from January 1, 2010, to December 19, 2020 were considered for inclusion. Quantitative and qualitative analysis was performed on the data collected.

Results:
A total of 28 articles meeting the inclusion criteria were identified and reviewed. With regard to objective functional outcome measures, such as strength, range of motion, or results of the Timed Up and Go (TUG) test, the virtual physical therapy group had equivalent or slightly superior outcomes compared with in-person physical therapy. There was similar improvement overall in patient-reported outcome measures (PROMs) and patient satisfaction between virtual and in-person physical therapy. Virtual physical therapy resulted in cost savings ranging from $206 to $4,100 per patient compared with in-person physical therapy.

Conclusions:
Telerehabilitation following lower-extremity joint replacement is less expensive compared with in-person physical therapy, with equivalent outcomes and patient satisfaction. Telerehabilitation and electronic health adjuncts can be used to substitute for traditional rehabilitation and augment postoperative care following total joint arthroplasty, respectively. Telerehabilitation that provides outcomes equivalent to in-person physical therapy not only increases convenience for patients but also decreases the cost burden on the health-care system.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Modernization of the brake system of unwinding on rope machines
Authors: Konovalchuk S. S. , Livshits I. M. 
Published: September 2021

In order to reduce the cost of producing metal cord in the hardware shops of OJSC “BSW” – the Management Company of the Holding “BMC”, work is underway to modernize and select materials for replaceable technological equipment. In the process of twisting the metal cord on the unwinding of the power coils of rope machines, brake devices are used, consisting of a disk and sectors (pads) fixed in a chain. The elements of the unwinding unit are in constant contact, providing the necessary tension force for unwinding a thin wire. The performance of the braking devices affects the manufacturability of the twist, the absence of breaks, the density and geometric arrangement of the wires in the twisted metal cord that meets the requirements of consumers.Due to constant contact friction at high linear speeds, the brake pads wear out, which leads to emergency operation of the equipment. The article considers the test results of the modified thin wire unwinding unit and the impact of modernization on the service life of brake pads.
The linkage between CO2, FDI, economic growth, and value-added: A European perspective
Authors: Singh Devesh 
Published: September 2021

Abstract
This article aims to investigate the linkage among CO2 emissions, Foreign Direct Investment (FDI), economic growth, Gross Value Added (GVA) of different sectors namely agriculture, service, manufacturing, and resource extensive industries including construction sectors in four European regions Eastern Europe (EE), Southern Europe (SE), Northern Europe (NE) and Western Europe (WE). This article uses the 3SLS simultaneous equation estimation during the period of 2000 to 2018. This study is the extension of seeing the challenges in policy implication in reducing CO2 emission in technologically rich economies. This article concluded that the causality among variables CO2 emission, economic growth, FDI, and all four sectors GVA is varied according to the regions. However, the CO2 emission has bidirectional causality with each industrial sector's GVA.
“Effect of Yoga Intervention on Skeletal Muscle Linked Glucose Homeostasis in Pre-Diabetic Individuals: Study Protocol for a Randomized Controlled Trial”
Authors: Bhalerao Supriya Sudhakar , Kharche Jayshree , Harke Shubhangi 
Published: September 2021

Abstract
Background- The pre-diabetic stage is important in terms of identification and timely management, as it is reversible. Along with other factors, insulin resistance in skeletal muscle is often considered as primary defect before development of overt hyperglycemia and diabetes. Proven to have many health benefits, Yoga has emerged as an effective measure in management of diabetes. As the Yogic postures are relatable to exercises, it was considered for improving skeletal muscle function and reverse the pre-diabetic stage.Methods- The present open, randomized clinical study is planned to evaluate the effect of Yoga interventions on muscle mass, strength, endurance and flexibility which are direct or indirect indicators of fat deposition in skeletal muscles. The study will also explore association between changes in muscle quality/ functionality and glycemic control. With Ethics committee permission, 120 pre-diabetic individuals of either sex between the age group of 35-49 years with a BMI in the range of 25-35 kg/m2 and family history of T2DM will be recruited in study after obtaining written informed consent. They will be randomly allocated to either Yoga or exercise group by computer generated randomized method in a 1:1 ratio. One group will receive defined Yoga interventions, while other group will receive fixed program of physical exercises. Both groups will undergo a training session for a period of 4 weeks under the supervision of a trained instructor, before 12-week study duration. The outcome measures will be parameters related to muscle quality/functionality and glucose metabolism markers. Discussion- Our study aims to study usefulness of Yoga in prediabetic stage on skeletal muscle related glycemic control, which is novel. In addition, the study will generate awareness about pre-diabetes and provide people with active coping skills for reversing it. Trial Registration- Clinical Trial Registry-India -CTRI/2019/05/019149, registered on: 15/05/2019
The network interplay of interferon and toll-like receptor signaling pathways in the anti-Candida immune response
Authors: Salgado Ranieri Coelho , Fonseca Dennyson Leandro M. , Marques Alexandre H. C. , Napoleao Sarah M. S. , Franca Tabata Takahashi , Akashi Karen Tiemi , Prado Caroline A. S. , Baiocchi Gabriela Crispim , Placa Desiree R. , Jansen-Marques Gabriel , Filgueiras Igor Salerno , De Vito Roberta , Freire Paula Paccielli , de Miranda Gustavo Cabral , Camara Niels Olsen Saraiva , Calich Vera L. G. , Ochs Hans D. , Schimke Lena F. , Jurisica Igor , Condino-Neto Antonio , Cabral-Marques Otavio 
Published: September 2021

Abstract
Fungal infections represent a major global health problem that affects over a billion people and kills more than 1.5 million individuals annually. Here we employed an integrative approach to unravel the landscape of the human immune responses to Candida spp. by performing a meta-analysis of microarray, bulk, and single-cell RNA-sequencing (RNASeq) of blood transcriptome data. We identified across these different studies a consistent interconnected network interplay of signaling molecules involved in both toll-like receptor (TLR) and interferon (IFN) signaling cascades that is activated in response to different Candida species (C. albicans, C. auris, C. glabrata, C. parapsilosis, and C. tropicalis). Among these molecules, there are several types I IFN, indicating an overlap with the anti-viral immune responses. scRNAseq data confirmed that genes commonly identified by the three transcriptomic methods present a cell-type specific expression patterns across innate and adaptive immune cells. Thus, these data shed new lights on the anti-candida immune response, providing putative molecular pathways for therapeutic intervention.
Unexpected Pneumoperitoneum: A Case Report
Authors: Munnings Amberley , Dooley Andrew , Singh Sandeep 
Published: September 2021

Abstract
Background:Pneumoperitoneum is usually the result of visceral perforation requiring urgent surgical repair. In rarer cases, no perforation is found despite the present of free intra-peritoneal air. This is otherwise known as “spontaneous pneumoperitoneum”.Case presentation:We present a case of an 18-year old male who had upper abdominal pain but who otherwise was not peritonitic and had normal blood results. He was concerned about the cause of the pain as he had previously had an admission to a different hospital with similar symptoms. A chest x-ray revealed unexpected pneumoperitoneum. Subsequent imaging revealed no identifiable perforation and the patient was managed without proceeding to an emergency laparotomy. Conclusion:This case demonstrates the importance of considering an erect chest x-ray in patients presenting with upper abdominal pain, with otherwise normal parameters, to avoid missing rarer diagnoses. Furthermore it demonstrates how such cases of spontaneous pneumoperitoneum can be managed conservatively, avoiding unnecessary surgery.
A Significant Role of MoO3 on the Optical, Thermal, and Radiation Shielding Characteristics of B2O3-P2O5 -Li2O Glasses
Authors: Shaaban kh. S. 
Published: September 2021

Abstract
Glasses based on borophosphate with the formula 42.5P2O5 – 42.5B2O3 – (15-x) Li2O – xMoO3 mol% where 𝑥 = (0 ≤ 𝑥 ≥ 15) were manufactured using the melt-quenching methodology. The status of prepared samples wasidentified by (XRD). The temperature of the glass transition Tg, the temperature of onset glass crystallisation Tc and the temperature of the crystallisation Tp were evaluated using a differential thermal analyser (DTA). The energy gap (𝐸𝑜𝑝𝑡), Urbach (𝐸𝑢), and parameters of dispersion were calculated through the data of optical spectra. Physical properties were determined and calculated, such as molar refractivity, metallization, electron polarizability, electronegativity, loss of reflection and dispersion parameters. Raising MoO3 at the expense of Li2O was used to assess the level of protection. For radiation protection applications, the glasses under investigation had superior characteristics.
Synthesis and Characterization of Lanthanum doped Co-Zn Spinel Ferrites Nanoparticles by Sol-Gel Auto Combustion Method
Authors: Gilani Zaheer Abbas , Farooq Amir , Asghar Hafiz Muhammad Noor ul Huda Khan , Khalid Muhammad , Shaikh Furhaj Ahmad , Islam Siraj ul , Tariq Muhammad Waqas , Nawaz Muhammad Kamran , Yasmeen Saira 
Published: September 2021

Abstract
Spinel ferrites nanoparticles play a significant role in our everyday lives. In the current work, La3+ doped Co-Zn ferrites with chemical formula Co0.5Zn0.5LaxFe2−xO4 (x = 0.00 to x = 0.2 with step size 0.04) was effectively prepared by sol gel technique. The formation of FCC spinel structure was confirmed by X-Ray diffraction (XRD) analysis. The average crystallite size were calculated to be in the 8 nm to 13 nm range. The lattice parameters were found to be decreased with the doping of lanthanum (La3+) contents. X- Ray density is analyzed to increase as the concentration of (La3+) doping increases, this is due to the fact that La3+ ion has a higher molar weight than Fe3+ ion. The spinel phase structure was affirmed by using FTIR.The two main absorption bands ν1 and ν2 are referred to tetrahedral stretching band and octahedral stretching band respectively, is found to be in the range of at around 400–530 cm− 1. Spinel ferrites, such as Co-Zn spinel ferrites, have dielectric features that make them ideal for use in high-frequency applications. With new potential applications being investigated all the time. Physical properties, synthesis method, as well as sintering temperature and time, are all important factors in regulating the properties of dielectric materials. The dielectric features were measured in the frequency of 1 MHz to 3 GHz range. Lowered dielectric parameters studied across a higher frequency range recommend that such nano crystalline ferrites could be used to fabricate the equipment needed to perform at GHz frequencies.
Opportunities and Challenges for Family-Centered Postpartum Care During the COVID-19 Pandemic: A Qualitative Study of Nurse Perspectives
Authors: Buek Katharine W. , O’Neil Molly , Mandell Dorothy J. 
Published: September 2021

Abstract
Background The global COVID-19 pandemic has forced the health care sector to make wide-ranging changes to protect patients as well as providers from the risk of infection. Many of these changes are likely to have greatest impact in contexts of care that employ family-centered models, including perinatal and maternity care. Research conducted in prenatal, childbirth and postpartum settings during the pandemic has shown that some of these restrictions have negatively impacted health care practice and outcomes, while others have been beneficial to both providers and patients. The present qualitative study aimed to understand what changes have occurred in postpartum nursing practice during the pandemic, and how these changes have affected nurses, women and families during their stay in the hospital following a new birth.MethodsStructured interviews were completed with 20 postpartum nurses from five hospitals across Texas. The interview protocol was designed to elicit information about changes to hospital policies in postpartum units during the pandemic, nurses’ attitudes about these changes, perceived benefits and challenges for performance of their duties, and perceived effects on patients and their families. Nurses were recruited for the study using a purposive sampling approach. Interviews were conducted by telephone and lasted approximately 30 to 45 minutes. Data were analyzed using a qualitative descriptive approach. ResultsParticipants reported that their hospitals placed restrictions on the number and mobility of support persons allowed to stay with the mother in the unit and prohibited all other visitation. Some challenges of these policies included reduced opportunities for hands-on learning and an increased number of patients opting for early discharge. Perceived benefits for nursing practice as well as patient outcomes included improved frequency and effectiveness of nurse-family communication, increased father involvement, and greater opportunities for maternal rest, breastfeeding, skin-to-skin care and family bonding.ConclusionsStudy findings suggests that some limitations on postpartum hospital visitation may achieve important, family-centered goals. Protected time for family-bonding, maternal rest, breastfeeding, father involvement and individualized education are critical to quality FCC. Research must examine which visitation policies maximize these benefits while preserving patient access to family and social support.
The Analysis and Probabilistic Health Risk Assessment of Polycyclic Aromatic Hydrocarbons in Cereal Products: with the Chemometric Approch
Authors: Khalili Fariba , Shariatifar Nabi , Dehghani Mohammad Hadi , Yaghmaeian Kamyar , Nodehi Ramin Nabizadeh , Yaseri Mehdi , Arabameri Majid 
Published: September 2021

Abstract
The analysis and probabilistic health risk assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in cereal products were done by using magnetic solid-phase extraction (MSPE) method and gas chromatography/mass spectrometric (GC/MS). The level of sum sixteen PAHs in cereal products ranged from 98.2 (in Barbari bread) to 248.3 µg/kg (in rice cooked). Further, the correlation between the type and amount of 16 PAHs with cereal products samples evaluated with multivariate principal component analysis and heat map visualization. Estimation of incremental lifetime cancer risk in cereals ranged from 7.80E-6 to 2.35E-7. In conclusion, the PAHs content in the tested products were in low health risk ranges (1 × 10 − 6 < ILCR < 1 × 10 − 4), and all of the cereal products sold in Tehran are considered safe for consumers. Therefore, cereal products should be regularly evaluated and monitored by regulatory agencies to reduce contaminants in these high-consumption products.
Validation of The 2018 FIGO Staging System for Predicting The Prognosis of Patients With Stage IIIC Cervical Cancer
Authors: Long Xingtao , Zhou Qi , Zou Dongling , Wang Dong , Liu Jingshu , Chen Yuemei 
Published: September 2021

Abstract
Purpose We aimed to validate the prognostic performance of the 2018 International Federation of Gynecology and Obstetrics(FIGO) IIIC staging system for patients with cervical cancer. Methods We conducted a retrospective analysis of patients with stage III cervical cancer according to the 2018 FIGO staging system who received standardized treatment from January 2011 to December 2014. Results Multivariable analysis revealed that stage IIIC1 was not significantly associated with increased risk of death compared with stages IIIA (hazard ratio [HR] = 1.432; 95% confidence interval [CI]: 0.867 to 2.366; P = 0.161) and IIIB (HR = 1.261; 95% CI: 0.871 to 1.827; P = 0.219). Stage IIIC2 was an independent indicator of increased risk of mortality compared with stages IIIA (HR = 2.958; 95% CI :1.757 to 4.983; P < 0.001) and IIIB (HR = 2.606; 95% CI: 1.752 to 3.877; P < 0.001). We stratified patients with stage IIIC1 according to T stage and compared survival outcomes. Stage IIIC1 (T1) was associated with longer 5-year overall survival (OS) compared with stages IIIA (P = 0.004) or IIIB (P < 0.001). An optimal cut-off value (= 2) was established for predicting the prognosis of stage IIIC1p(T1/T2a), which was associated with the number of pelvic lymph nodes metastases (PLNMs). Patients with stage IIIC1pN1-2 experienced longer 5-year OS compared those with stages IIIA (P = 0.01) or IIIB (P < 0.001). Conclusion Patients with stage IIIC1 cervical cancer exhibited heterogeneous clinical characteristics reflecting their variable prognoses, depending on T-stage and the extent of PLNMs