bluuebunny/crossref_metadata_2025_split huggingface dataset:
Motivation behind running among older adult runners
Authors: León-Guereño Patxi , Galindo-Domínguez Héctor , Balerdi-Eizmendi Eneko , Rozmiarek Mateusz , Malchrowicz-Mośko Ewa 
Published: October 2021

Abstract
Background
Recreational running has greatly increased over the last decade, and different research has tried to understand the motivation that leads these amateur athletes to run. However, most research has focused on adult athletes, while the motivation behind older adult athletes has been overlooked.

Methods
The aim of this research was to analyse the motivational aspects of amateur runners aged over 50 years, and to consider the influence that years of practice, type of participation and some socio-demographical variables have on these older adults’ motivation behind running. 244 older adult amateur athletes in total completed an online survey with the 56 items contained in the motivation of marathoners scales (MOMS), 108 of whom were female (44%), and 136 were male runners (56%). Athletes were asked about their years’ running experience (< 1 year, 1–5 years, 6–10 years, > 10 years), their participation in running events (recreationally, half marathon, marathon, ultramarathon) and age (ranges 50–60, more than 60 years), gender (male, female), family life (whether in a relationship or not), and whether they had children (yes, no).

Results
The results showed statistical differences in the nine MOMS dimensions in terms of years’ running experience and participation in different running events. Moreover, older adult runners’ gender and age subsequently showed statistical differences with five and six motivational factors respectively, while athletes that did not have children were more likely to run regarding competition and showing recognition. Family life did not show any statistical association with any of the dimensions on the scale in this population, while regression analyses showed that, mainly, years’ running experience and participation were positively predicted, together with most motivational dimensions, while having children was negatively predicted in some of them.

Conclusions
This study showed that older adult runners’ reasons for participating differ from those obtained in previous studies, especially regarding training experience and participation in events. Therefore, the older adult population should be specifically addressed.
Histamine binding activity of surface-modified yeast by histamine binding protein (HBP)
Authors: Jang Hyeweon , Lee Geun Woo , Kim Yang-Hoon , Min Jiho 
Published: October 2021

AbstractHistamine is an immune mediator that is mainly secreted when an immediate, rapid response is needed in the body, and an excessive secretion of histamine or lack of enzymes that degrade histamine can result in various side effects. Histamine binding protein (HBP) is secreted by a mite species to prevent the host’s histamine-induced immune responses by binding the histamine molecule in the blood. Cloning was performed to express HBP on the yeast surface (MBTL-GWL-1), and immunofluorescence (IF) and western blot was performed to confirm the expression of the recombinant protein. The histamine inhibitory ability of GWL-1 cells was tested according to the cell concentration. The highest inhibitory ability of 1.30 × 107 CFU/ml of GWL-1 cells was of about 60 %. The GWL-1 cell concentration and the degree of histamine inhibition were confirmed to be dose-dependent, and dead cell debris was shown to have a histamine inhibitory effect, although not as much as that of whole cells. Phagocytosis assays were performed to determine whether histamine affected the RAW 264.7 cell’s phagocytosis, and to indirectly confirm the GWL-1 cell’s histamine inhibition. By confirming that, we found that GWL-1 captures histamine. Therefore, it can be expected to become a competitive material in the anti-allergy market.
Practices and intravascular catheter infection during on- and off-hours in critically ill patients
Authors: Buetti Niccolò , Ruckly Stéphane , Lucet Jean-Christophe , Mageau Arthur , Dupuis Claire , Souweine Bertrand , Mimoz Olivier , Timsit Jean-François 
Published: October 2021

Abstract
Background
The potential relationship between intravascular catheter infections with their insertion during weekend or night-time (i.e., off-hours or not regular business hours) remains an open issue. Our primary aim was to describe differences between patients and catheters inserted during on- versus off-hours. Our secondary aim was to investigate whether insertions during off-hours influenced the intravascular catheter infectious risks.

Methods
We performed a post hoc analysis using the databases from four large randomized-controlled trials. Adult patients were recruited in French ICUs as soon as they required central venous catheters or peripheral arterial (AC) catheter insertion. Off-hours started at 6 P.M. until 8:30 A.M. during the week; at weekend, we defined off-hours from 1 P.M. on Saturday to 8.30 A.M. on Monday. We performed multivariable marginal Cox models to estimate the effect of off-hours (versus on-hours) on major catheter-related infections (MCRI) and catheter-related bloodstream infections (CRBSIs).

Results
We included 7241 patients in 25 different ICUs, and 15,208 catheters, including 7226 and 7982 catheters inserted during off- and on-hours, respectively. Catheters inserted during off-hours were removed after 4 days (IQR 2, 9) in median, whereas catheters inserted during on-hours remained in place for 6 days (IQR 3,10; p < 0.01) in median. Femoral insertion was more frequent during off-hours. Among central venous catheters and after adjusting for well-known risk factors for intravascular catheter infection, we found a similar risk between off- and on-hours for MCRI (HR 0.91, 95% CI 0.61–1.37, p = 0.65) and CRBSI (HR 1.05, 95% CI 0.65–1.68, p = 0.85). Among central venous catheters with a dwell-time > 4 or > 6 days, we found a similar risk for MCRI and CRBSI between off- and on-hours. Similar results were observed for ACs.

Conclusions
Off-hours did not increase the risk of intravascular catheter infections compared to on-hours. Off-hours insertion is not a sufficient reason for early catheter removal, even if femoral route has been selected.
Aetiology and outcome of non-traumatic coma in African children: protocol for a systematic review and meta-analysis
Authors: Ray Stephen T. J. , Fuller Charlotte , Boubour Alexandra , Bonnett Laura J. , Lalloo David G. , Seydel Karl B. , Griffiths Michael J. 
Published: October 2021

Abstract
Background
Non-traumatic coma is a common acute childhood presentation to healthcare facilities in Africa and is associated with high morbidity and mortality. Historically, the majority of cases were attributed to cerebral malaria (CM). With the recent drastic reduction in malaria incidence, non-malarial coma is becoming a larger proportion of cases and determining the aetiology is diagnostically challenging, particularly in resource-limited settings. The purpose of this study will be to evaluate the aetiology and prognosis of non-traumatic coma in African children.

Methods
With no date restrictions, systematic searches of MEDLINE, Embase, and Scopus will identify prospective and retrospective studies (including randomised controlled trials, cluster randomised trials, cohort studies, cross-sectional, and case-control studies) recruiting children (1 month–16 years) with non-traumatic coma (defined by Blantyre Coma Score ≤ 2 or comparable alternative) from any African country. Disease-specific studies will be included if coma is associated and reported. The primary outcome is to determine the aetiology (infectious and non-infectious) of non-traumatic coma in African children, with pooled prevalence estimates of causes (e.g., malaria). Secondary outcomes are to determine overall estimates of morbidity and mortality of all-cause non-traumatic coma and disease-specific states of non-traumatic coma, where available. Random effects meta-analysis will summarise aetiology data and in-hospital and post-discharge mortality. Heterogeneity will be quantified with τ2, I2, and Cochran’s Q test.

Discussion
This systematic review will provide a summary of the best available evidence on the aetiology and outcome of non-traumatic coma in African children.

Systematic review registration
PROSPERO CRD42020141937
Asymptotic pointwise error estimates for reconstructing shift-invariant signals with generators in a hybrid-norm space
Authors: Li Haizhen , Fan Xiao , Tang Yan 
Published: October 2021

AbstractSampling and reconstruction of signals in a shift-invariant space are generally studied under the requirement that the generator is in a stronger Wiener amalgam space, and the error estimates are usually given in the sense of $L_{p,{1 / \omega }}$

L

p
,
1
/
ω

-norm. Since we often need to reflect the local characteristics of reconstructing error, the asymptotic pointwise error estimates for nonuniform and average sampling in a non-decaying shift-invariant space are discussed under the assumption that the generator is in a hybrid-norm space. Based on Lemma 2.1–Lemma 2.6, we first rewrite the iterative reconstruction algorithms for two kinds of average sampling functionals and prove their convergence. Then, the asymptotic pointwise error estimates are presented for two algorithms under the case that the average samples are corrupted by noise.
Cyberchondria severity and quality of life among Lebanese adults: the mediating role of fear of COVID-19, depression, anxiety, stress and obsessive–compulsive behavior—a structural equation model approach
Authors: Rahme Clara , Akel Marwan , Obeid Sahar , Hallit Souheil 
Published: October 2021

Abstract
Background
This study highlights the significant association between cyberchondria and quality of life among the Lebanese population in the time of COVID-19. The aim was to assess the association between cyberchondria and quality of life (QOL) of Lebanese community during the COVID-19 pandemic and assess the mediating effect of fear of COVID-19, depression, anxiety, stress and Yale-Brown Obsessive–Compulsive Scale in this association.

Methods
This cross-sectional study was carried out between December 2020 and January 2021, during the COVID-19 pandemic. A total of 449 persons participated in this study by filling the online questionnaire. Structural equation modeling (SEM) was performed to examine the structural relationship between cyberchondria severity, the mediator (anxiety, stress, depression, obsessive–compulsive disorder (OCD) and fear of COVID-19) and physical/mental QOL.

Results
Having a university level of education and older age were significantly associated with higher physical QOL scores, whereas higher obsession-compulsion disorder, higher stress and higher anxiety were significantly associated with lower physical QOL scores. Higher anxiety was significantly associated with lower mental QOL scores. The results of the SEM showed that stress, fear of COVID-19 and to a lesser limit OCD, mediated the association between cyberchondria severity and physical QOL, whereas anxiety, stress and fear of COVID-19 mediated the association between cyberchondria severity and mental QOL.

Conclusion
This research reported interesting results encouraging more exploration of cyberchondria and its association with quality of life during this unique period of the pandemic. However, this virus has altered the lives of individuals all across the world, and the consequences will last for a long time. Along with all of the steps done to stop the development of COVID-19 and improve physical outcomes, mental health requires immediate care. More research is needed to determine the coping techniques people are employing to deal with the pandemic.
iHear: Canadian medical student based hearing assessment program for grade school children using a tablet audiometer
Authors: Lammers Deanna , Rocker Adam , Chan David S. , Couchman Deema , Wang Yiqiao , Fraser Amy , MacCormick Johnna , Bromwich Matthew 
Published: October 2021

Purpose To evaluate the progress and challenges of a hearing screening program as well as review the incidence of pediatric hearing loss in grade school children participating in this program. Methods Medical students from the University of Ottawa established iHear, a grade school hearing assessment program that uses novel tablet audiometry. Over 3 years, children in grades 1 and 2 were assessed and those found to have abnormal results on iHear assessment were then referred to audiology for formal testing, and to otolaryngology if needed. Results From 2014 to 2017, 753 children aged 5–9 years old were assessed for hearing loss. Mean age of participants was 6.7 years, 51.9% of whom were female. Of the children assessed, 86 (11.4%) had abnormal results and 6 (0.8%) had inconsistent results, necessitating 92 referrals for assessment by a professional audiologist. Of the 65 participants who completed secondary audiologic assessment, 54 (83.1%) were normal and 11 (16.9%) had a definitive hearing loss or abnormal tympanometry. A total of 32 children were lost to follow-up. A total of 118 medical students were involved in the iHear program. Conclusions Hearing loss in grade school populations continues to go undetected across Canada. Programs such as iHear demonstrate that gaps in the provision of hearing assessment can be filled effectively by medical students equipped with tablet audiometry. Medical student exposure to audiology and otolaryngology increased through the iHear program. Graphical Abstract
Effect of orthopaedic resident education on screening for intimate partner violence
Authors: Peters Mikaela J. , Roffey Darren M. , Lefaivre Kelly A. 
Published: October 2021

Abstract
Background
Intimate Partner Violence (IPV) is prevalent in women presenting to orthopaedic fracture clinics. Rates of IPV have increased during the COVID-19 global pandemic. Our aim was to determine the effect of educational experiences on IPV knowledge and IPV screening to inform best-practices in resident education.

Methods
Cross-sectional online survey of orthopaedic surgery residency programs in Canada. Demographics, IPV educational experiences, IPV knowledge, and frequency of IPV screening were collected via a modified version of the Physician Readiness to Manage Intimate Partner Violence Survey (PREMIS). Descriptive statistics and regression modeling identified predictors of IPV knowledge and frequency of IPV screening.

Results
Responses were obtained from 105 orthopaedic residents; 84% participated in classroom training, 39% underwent mentorship training, 32% received both classroom training and mentorship, and 10% reported neither. Classroom training had no statistically significant association with IPV knowledge or frequency of IPV screening. Residents who received mentorship were 4.1 times more likely to screen for IPV (95% CI: 1.72–10.05), older residents were more likely to screen for IPV (OR: 8.3, 95% CI: 2.64–29.84), and senior residents were less likely to screen for IPV than junior residents (OR: 0.29, 95% CI: 0.09–0.82).

Conclusions
Classroom training was not associated with any effect on IPV knowledge nor the frequency of IPV screening. Educational efforts should be targeted at increasing mentorship opportunities in order to improve IPV screening practices in Canadian orthopaedic residents.
Variations of crustal thickness and average Vp/Vs ratio beneath the Shanxi Rift, North China, from receiver functions
Authors: Chen Yifang , Chen Jiuhui , Li ShunCheng , Yu Zhanyang , Liu Xuzhou , Shen Xuzhang 
Published: October 2021

AbstractThe Shanxi Rift located in the central part of the North China Craton (NCC) as a boundary between the Ordos block and the Huabei basin. The Shanxi graben system is a Cenozoic rift and originated from back-arc spreading related to westward subduction of the western Pacific and far field effects caused by northward subduction of the Indian plate. It has also had strong earthquake activity in China since the Quaternary. To investigate the tectonic evolution and tectonic setting of strong earthquakes in the Shanxi Rift, we apply the receiver function $$H$$
H
-$$\kappa$$
κ
stacking method to determine the crustal thickness and average Vp/Vs ratio in the area. The results show that the thickness of the crust increases from approximately 30 km in the Huabei basin to approximately 47 km in the Yinshan Mountains with a close correlation between the Moho depth and topography. The Yuncheng, Linfen and Taiyuan grabens have varying degrees of crustal thinning. The crustal average Vp/Vs ratio in the Shanxi Rift has significant heterogeneity; the high Vp/Vs ratio (~ 1.85) are found in the Datong and Yuncheng grabens, and Vp/Vs ratio of the Taiyuan and Linfen grabens is approximately 1.75 which close to the global average value ~ 1.782. Combining the observations in this study with previous research, we suggest that the grabens in the Shanxi Rift experienced extensional deformation from south to north and that the possibility of strong earthquakes in the central part of the Shanxi seismic belt is greater than that on the northern and southern sides.
Corporate social responsibility in international business literature: results from text data mining of the Journal of International Business Studies
Authors: Paul Karen , Parra Carlos M. 
Published: October 2021

AbstractCorporate social responsibility has been an important theme in management at least since the 1960s. International business became a recognized subfield in management around the same time. Logically, there might have been much dialogue about corporate social responsibility in international business research and publication, yet previous reviews of the literature indicate relatively little such research. This study complements previous literature reviews by employing text data mining to analyze a sample of 1188 articles published from 2000 to 2018 in the Journal of International Business Studies (JIBS). Results show that from 2000 to 2018 only 35 CSR focused articles appeared. CSR research has increased over time, highly influenced by editorial specification of special issues. These documents can be grouped into seven CSR topics, with corruption and embeddedness being the most salient. Strategies are suggested for increasing research on CSR in international business.
Training muscle activation patterns of the lower paretic extremity using directional exertion improves mobility in persons with hemiparesis: a pilot study
Authors: Bourbonnais Daniel , Pelletier René , Azar Joëlle , Sille Camille , Goyette Michel 
Published: October 2021

AbstractBackgroundControlled static exertion performed in the sagittal plane on a transducer attached to the foot requires coordinated moments of force of the lower extremity. Some exertions and plantarflexion recruit muscular activation patterns similar to synergies previously identified during gait. It is currently unknown if persons with hemiparesis following stroke demonstrate similar muscular patterns, and if force feedback training utilizing static exertion results in improved mobility in this population.MethodsElectromyographic (EMG) activity of eight muscles of the lower limb were recorded using surface electrodes in healthy participants (n = 10) and in persons with hemiparesis (n = 8) during an exertion exercise (task) performed in eight directions in the sagittal plane of the foot and a plantarflexion exercise performed at 20 and 40% maximum voluntary effort (MVE). Muscle activation patterns identified during these exertion exercises were compared between groups and to synergies reported in the literature during healthy gait using cosine similarities (CS). Functional mobility was assessed in four participants with hemiparesis using GAITRite® and the Timed Up and Go (TUG) test at each session before, during and after static force feedback training. Tau statistics were used to evaluate the effect on mobility before and after training. Measures of MVE and the accuracy of directional exertion were compared before and after training using ANOVAs. Spearman Rho correlations were also calculated between changes in these parameters and changes in mobility before and after the training.ResultsMuscle activation patterns during directional exertion and plantarflexion were similar for both groups of participants (CS varying from 0.845 to 0.977). Muscular patterns for some of the directional and plantarflexion were also similar to synergies recruited during gait (CS varying from 0.847 to 0.951). Directional exertion training in hemiparetic subjects resulted in improvement in MVE (p < 0.040) and task performance accuracy (p < 0.001). Hemiparetic subjects also demonstrated significant improvements in gait velocity (p < 0.032) and in the TUG test (p < 0.022) following training. Improvements in certain directional efforts were correlated with changes in gait velocity (p = 0.001).ConclusionStatic force feedback training following stroke improves strength and coordination of the lower extremity while recruiting synergies reported during gait and is associated with improved mobility.
Role of diffusion-weighted MRI in evaluation of pediatric musculoskeletal soft tissue masses
Authors: El-Adalany Mohamed Ali , Eid Nevertiti Kamal El-Din , Othman Salma , El-Metwally Dina 
Published: October 2021

Abstract
Background
In pediatric patients, soft tissue masses encompass a wide heterogeneous group of benign and malignant lesions. MRI is a powerful diagnostic tool in the workup of soft tissue tumors in children, and it helps in characterization of lesion and evaluation of the extent of the lesion. However, conventional MRI techniques are not specific in differentiating benign from malignant lesions. So to improve characterization of tumors, DWI was added to MRI techniques as it increases sensitivity and specificity by detecting the micro-diffusion changes of water into intra- and extracellular spaces. The aim of this work was to highlight the diagnostic value of DWI in detection and characterization of different musculoskeletal soft tissue masses in pediatrics.

Results
There was a statistically significant difference regarding the mean ADC value of benign and malignant masses (P value = 0.001*). The mean ADC value for all benign masses (n = 41) was 1.495 ± 0.55 SD × 10–3 mm2/s, while the mean ADC value for all malignant masses (n = 21) was 0.449 ± 0.27 SD × 10–3 mm2/s. The cutoff ADC value between benign and malignant masses was 0.88 × 10–3 mm2/s. This cutoff ADC value has sensitivity of 100.0%, specificity of 92.3%, PPV of 66.7%, NPV of 100.0% and diagnostic accuracy of 93.3%.

Conclusion
In pediatric patients, DWI is an innovative valuable noninvasive imaging technique for characterization of musculoskeletal soft tissue masses and discrimination between benign and malignant masses.