bluuebunny/crossref_metadata_2025_split huggingface dataset:
Abstract 108: The Relationship Between Cervical Cancer and Women Living with Disabilities in Kentucky
Authors: Akakpo Carolyn 
Published: July 2021

Abstract
Purpose: Despite many national interventions, cervical cancer (CC) rates persist, and in Kentucky (KY), CC incidence rates are on the rise. Additionally, women with disabilities are medically underserved and face more barriers to secondary prevention and healthcare access, have more known risks, and experience more health disparities than women without disabilities. Given that 1 in 4 persons live with a disability in the USA, the purpose of this observational, cross-sectional, quantitative study was to explore the relationship between CC and women with disabilities as evidenced by reproductive cancer discharges from inpatient hospital (IHD) and outpatient services databases (OSD) so as to compare population-specific differences from social determinants of health framework.
Methods: Data from the Kentucky Cabinet for Health and Family Services for 2015 to 2018 were analyzed using MLR. In total, the sample included 584 women with disabilities and 32,773 women without disabilities living in KY. Results: The IHD data analysis found that county of residence (p =.014) and insurance payer (p = .000) were statistically significant and that women on public insurance were 9.6 times as likely to be diagnosed with CC.
Results: of the OSD data analysis found that place of residence (p = .000) and age group (p = .000) were statistically significant and that women aged 40-44 were 9.5 and 2.9 times as likely to have breast cancer and CC respectively.
Conclusion: This study's findings call for; greater attention to strengthening public health surveillance and infrastructure affording visibility of women with disabilities who are underserved, increased proportion of breast and cervical cancer screening at an early age, and increase health access interventions for low resource settings.
Citation Format: Carolyn Akakpo. The Relationship Between Cervical Cancer and Women Living with Disabilities in Kentucky [abstract]. In: Proceedings of the 9th Annual Symposium on Global Cancer Research; Global Cancer Research and Control: Looking Back and Charting a Path Forward; 2021 Mar 10-11. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2021;30(7 Suppl):Abstract nr 108.
Abstract 113: Burden of Risk Factors for Cervical Cancer among Women Living In East Africa: Analysis of the Latest Demographic Health Surveys Conducted between 2014 And 2017
Authors: Abila Derrick , Ainembabazi Provia , Wasukira Sulaiman , Wabinga Henry 
Published: July 2021

Abstract
Purpose: In East Africa, cervical cancer is a leading cause of morbidity and mortality amongst women diagnosed with cancer in East Africa. We aimed to describe the burden of risk factors for cervical cancer among women of reproductive age in five East African countries to inform the design of interventions to the reduce exposure of women to them.
Methods: For each country, using STATA13 and sampling weights, we analysed Demographic and Health Survey (DHS) datasets conducted between 2014 and 2017 in Burundi, Kenya, Rwanda, Tanzania, and Uganda. The surveys followed a two-stage cluster random sampling procedure. We included women aged 15 to 49 years and considered six risk factors (tobacco use, body mass index, age at first sexual intercourse, age at first birth, number of children and hormonal contraceptive use). Poisson regression was used to determine the demographics associated with the number of risk factors a woman had.
Results: From 93,616 women from the countries, each country had more than half younger than 30 years of age with majority living in rural areas. Pooled proportion of women with at least one risk factor was 89% (95% Confidence interval, CI 87% - 91%). Living in a rural area in Burundi (Adjusted Incidence Rate Ration, aIRR 0.94; 95% CI: 0.9–0.99; p = 0.019) and Rwanda [aIRR 0.92; 95% CI: 0.88 - 0.96; p &lt; 0.001] was associated with a lower number of risk factors among women compared with living in an urban area. In all the countries, women with complete secondary education were associated with the lowest number of risk factors for cervical cancer compared with those living in urban areas.
Conclusion: Our study revealed a high burden of risk factors for cervical cancer in East Africa with a high proportion of women having at least one risk factor.
Citation Format: Derrick Abila, Provia Ainembabazi, Sulaiman Wasukira, Henry Wabinga. Burden of Risk Factors for Cervical Cancer among Women Living In East Africa: Analysis of the Latest Demographic Health Surveys Conducted between 2014 And 2017 [abstract]. In: Proceedings of the 9th Annual Symposium on Global Cancer Research; Global Cancer Research and Control: Looking Back and Charting a Path Forward; 2021 Mar 10-11. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2021;30(7 Suppl):Abstract nr 113.
Abstract 114: Funders and Collaborators of Cancer Research in Kenya, 2007-2017: A Bibliometric Analysis
Authors: Vargas Jasmin , Joseph Anyona , Maina Martha , Karagu Alfred , Cira Mishka , Lu Ya-Ling , Livinski Alicia 
Published: July 2021

Abstract
Purpose: It is well established that cancer research is essential to the development and implementation of effective control strategies and interventions. In Kenya, cancer is the third leading cause of death. Country specific research conducted by both local and international investigators has the potential to shape a national plan which addresses local needs across the cancer care continuum. This analysis aims to provide information about the trends in research collaborations, funding and outputs from 2007-2017 types of research collaborations, institutional and individual research collaborations, the types of cancer in order to understand gaps and opportunities to strengthen Kenya-led cancer research capacity.
Methods: This analysis included 243 studies from a previously published phase 1 scoping review of oncology research conducted in Kenya from 2007-2017. The citation metadata was drawn from Pubmed and manually standardized in Microsoft Excel. Using Sci2, a series of bibliometric network analyses were conducted to identify funding patterns, collaborations between authors and institutions, and the types of cancer research conducted in Kenya. Gephi and Excel provided descriptive analyses and graphs of the network. The analyses are categorized into three themes: article production, collaboration, and research topics. These findings were contextualized by study co-authors from Kenya and the US.
Results: The bibliometric analysis described which agencies are funding cancer research in Kenya, which authors and institutions are collaborating with whom, and the cancer research areas most published on in this dataset. The publication trend from 2007-2017 was highlighted, emphasizing the historical development and enabling important recognition of researchers and funders in advancing medical oncology in Kenya.
Conclusion: This study identifies future areas for collaborations between investigators in similar sub-fields and cancer research funding priorities for the nation. The findings provide a bigger picture that will guide policymakers on developing evidence-based decision-making, planning to strengthen future research capacity, and funding.
Citation Format: Jasmin Vargas, Anyona Joseph, Martha Maina, Alfred Karagu, Mishka Cira, Ya-Ling Lu, Alicia Livinski. Funders and Collaborators of Cancer Research in Kenya, 2007-2017: A Bibliometric Analysis [abstract]. In: Proceedings of the 9th Annual Symposium on Global Cancer Research; Global Cancer Research and Control: Looking Back and Charting a Path Forward; 2021 Mar 10-11. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2021;30(7 Suppl):Abstract nr 114.
Abstract 13: High-Throughput, Non-Invasive Raman Spectroscopy of Anticancer Nanomedicine for Liver Cancer Therapeutic Intervention
Authors: Poojari Radhika , Bhujbal Mithila , Hole Arti , Chilakapati Murali Krishna 
Published: July 2021

Abstract
Purpose: Liver cancer remains one of the most difficult to treat, heterogeneous forms of cancer with poor prognosis. Available current therapies face many limitations. Raman spectroscopy is a promising platform for clinical drug development and surgical interventions for improved patient outcomes. Herein, we present a new insight with a rapid, non-destructive, non-invasive Raman spectroscopy modality based molecular signatures unique to anticancer nanomedicine signifying distinct stratification in liver cancer treated tissues of SCID mice.
Methods: The therapeutic intervention was investigated using a high-throughput Raman spectroscopy in ex vivo liver tissues treated with combinatorials; targeted and non-targeted polymeric nanocomplexes encapsulated microtubule inhibitors against metastatic liver cancer in SCID mice. Principal Component Analysis (PCA), Linear Discriminate Analysis (LDA) for multivariate data analysis, and cross validation method was used to extrapolate the high throughput Raman based treatment efficiency study in ex vivo liver tissues.
Results: Raman spectral signatures obtained by Raman spectroscopy of liver tissue samples of healthy normal liver versus liver cancer cohorts exhibited complete discrimination of healthy ones from the affected diseased counterparts with high accuracy classification. This could be useful as a liver cancer diagnosis tool. Peculiar Raman profiles with distinct stratification of targeted anticancer nanomedicine combinatorials treated cohort were observed. Interestingly, apoptotic lipid bodies and amide I was the prominent features revealed in anticancer nanomedicine combinatorials treatment cohorts.
Conclusion: Our approach is a significant advancement for unique Raman molecular signatures-based targeted anticancer nanomedicine combinatorials therapeutic intervention for liver cancer in tissues. Clinical translation of this proposed modality would define Raman based rapid, high-throughput platform for the clinical drug development and monitoring against liver cancer remains warranted.
Citation Format: Radhika Poojari, Mithila Bhujbal, Arti Hole, Murali Krishna Chilakapati. High-Throughput, Non-Invasive Raman Spectroscopy of Anticancer Nanomedicine for Liver Cancer Therapeutic Intervention [abstract]. In: Proceedings of the 9th Annual Symposium on Global Cancer Research; Global Cancer Research and Control: Looking Back and Charting a Path Forward; 2021 Mar 10-11. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2021;30(7 Suppl):Abstract nr 13.
Abstract 19: Geospatial Analysis and Impact of Targeted Development of Breast Cancer Care in The Gambia: A Cross-Sectional Study
Authors: Lopez-Verdugo Fidel , Mali Meghan , Moustafa Moustafa , Nellermoe Jonathan , Sorensen Justin , Bittaye Mustapha , Njie Ramou , Singhateh Yankuba , Goldsmith Alison , Mohammed Nuredin I. , Price Raymond R. , Sutherland Edward , Sanyang Ousman 
Published: July 2021

Abstract
Purpose: To characterize the capacity of healthcare facilities to provide breast cancer care in The Gambia and calculate the proportion of the population with access to services.
Methods: A facility-based service assessment tool was administered to all healthcare facilities in The Gambia. Proximity of service availability and population analysis were assessed using GPS coordinates and LandScan population density raster. Distance thresholds of 10km, 25km, and 45km were established to determine access to screening services, pathologic diagnosis, and surgical management, respectively. An additional population analysis was performed to observe the potential impact of targeted resource development.
Results: All 102 healthcare facilities were included. Breast cancer screening was mainly performed through clinical breast examination and was available in 52 facilities. Seven facilities provided pathologic diagnosis and surgical management of breast cancer. The proportion of the Gambian population with access to screening, pathologic diagnosis and surgical management was 72%, 57%, and 62%, respectively. Patients living on the eastern side of the country have to travel up to 35 km for screening services and up to 300 km for pathologic diagnosis and surgical management. Widespread implementation of clinical breast examination for screening, and targeted expansion of diagnostic and surgical resources in two hospitals would increase the covered population to 95%, 67%, and 84%. This would decrease the maximum distance to access breast cancer care to 15 km for screening and 90 km for diagnosis and surgical management.
Conclusion: Almost half of the Gambian population do not have access to pathologic diagnosis and surgical management of breast cancer within a reasonable travel distance, and all facilities offering these services are located in the capital city. Mapping and population analysis can identify key areas of need. This approach allows targeted development of resources to significantly increase access to breast cancer care in a low resource setting.
Citation Format: Fidel Lopez-Verdugo, Meghan Mali, Moustafa Moustafa, Jonathan Nellermoe, Justin Sorensen, Mustapha Bittaye, Ramou Njie, Yankuba Singhateh, Alison Goldsmith, Nuredin I. Mohammed, Raymond R. Price, Edward Sutherland, Ousman Sanyang. Geospatial Analysis and Impact of Targeted Development of Breast Cancer Care in The Gambia: A Cross-Sectional Study [abstract]. In: Proceedings of the 9th Annual Symposium on Global Cancer Research; Global Cancer Research and Control: Looking Back and Charting a Path Forward; 2021 Mar 10-11. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2021;30(7 Suppl):Abstract nr 19.
Abstract 21: Mapping Breast Cancer Resource Availability Across Ghana's Eastern Region
Authors: Moustafa Moustafa , Mali Meghan , Lopez-Verdugo Fidel , Sanyang Ousman , Ayensu-Danquah Grace , Sorensen Justin , Nellermoe Jonathan , Manortey Stephen , Goldsmith Alison , Ofei Irina , Biritwurm-Nyarko Alberta , Price Raymond , Sutherland Edward 
Published: July 2021

Abstract
Purpose: Improve allocation of breast cancer resources across Ghana's Eastern Region by systematically assessing and mapping breast cancer screening, diagnosis, and treatment capacity.
Methods: A survey to assess breast cancer care capacity was developed and administered to hospitals in the Eastern Region of Ghana. Hospitals were stratified based on their available services. All facilities were mapped using GPS coordinates to demonstrate the location and distance between key services using thresholds of 10, 25, and 45km for screening, diagnostic, and surgical treatment capacity respectively.
Results: Thirty-three (out of 34) hospitals in the Eastern Region were surveyed: 27 (82%) hospitals provide basic screening services (clinical diagnosis with clinical breast exam), 11 (33%) provide pathologic diagnosis, and 3 (9%) provide those services in addition to basic surgical care. A total of 53% of the population lives within a 10km travel distance of screening services, 64% within 25km of diagnostic services, and 78% within 45km of surgical treatment. Ninety-four percent of facilities have a general practitioner; 55% have a radiology technician; 39% employ a surgeon. Oncology specialists, and pathology personnel are only available in 1 facility across the Eastern Region. Limited chemotherapy is available at 2 hospitals, endocrine therapy at 1 hospital, and radiotherapy is not available.
Conclusion: No hospitals are able to provide the full spectrum of care outlined by the Basic NCCN Framework Guidelines, which are intended for use in low resource settings. Although 82% of hospitals provide screening, only half the population lives within reasonable distance of these services. Few hospitals offer diagnosis and surgical treatment services. This geospatial analysis suggests two priorities in order to cost-effectively expand breast cancer services: increase the quantity of screening hospitals in targeted locations, and enhance treatment services at hospitals already providing diagnosis and surgery.
Citation Format: Moustafa Moustafa, Meghan Mali, Fidel Lopez-Verdugo, Ousman Sanyang, Grace Ayensu-Danquah, Justin Sorensen, Jonathan Nellermoe, Stephen Manortey, Alison Goldsmith, Irina Ofei, Alberta Biritwurm-Nyarko, Raymond Price, Edward Sutherland. Mapping Breast Cancer Resource Availability Across Ghana's Eastern Region [abstract]. In: Proceedings of the 9th Annual Symposium on Global Cancer Research; Global Cancer Research and Control: Looking Back and Charting a Path Forward; 2021 Mar 10-11. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2021;30(7 Suppl):Abstract nr 21.
Abstract 23: Oncology Nurse Mentor, a Model to Offer Training and Continued Mentorship to General Nurses in Low Resource Setting
Authors: Wambasi David , Achieng Emmah , Were Pamela 
Published: July 2021

Abstract
Purpose: The GLOBOCAN report for 2018 estimated 47,887 new cases of cancer annually with a mortality of 32, 987 in Kenya. Low income countries face a growing burden of cancer and a shortage of specialized Oncology nurses to meet the need. Partnerships between centers with specialised oncology nurses and counties that are setting up oncology units can be a bridge to improve access to remote sites in LMIC countries.
Methods: The International Cancer Institute (ICI) partnered with four counties Meru, Makueni, Sori and Taita Taveta to set up oncology centers in remote areas. Unspecialised nurses interested in oncology care were selected from the four counties and were offered short courses in oncology. Oncology nurses then travel to the sites on a three weekly basis for further on job training and mentorship. Continuous medical education is done on all aspects of nursing oncology management including assessment of patients, care of the patients, screening and chemotherapy.
Results: When the program started the oncology nurses from Eldoret travelled to the sites every three weeks but gradually this was reduced and phone and tele consults encouraged. Distance from Eldoret to the four sites is Meru (168 Miles), Makueni (228 Miles), Sori lakeside (99 Miles) and Taita Taveta (353 Miles). Two sites are now independent and run on their own on a daily basis. Eight nurses have been trained and mentored.
Conclusion: Capacity building through on job training and mentorship by the specialised Oncology nurses to general nurses has demonstrated improved access to oncology care in low resource settings over a shorter duration of time.
Citation Format: David Wambasi, Emmah Achieng, Pamela Were. Oncology Nurse Mentor, a Model to Offer Training and Continued Mentorship to General Nurses in Low Resource Setting [abstract]. In: Proceedings of the 9th Annual Symposium on Global Cancer Research; Global Cancer Research and Control: Looking Back and Charting a Path Forward; 2021 Mar 10-11. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2021;30(7 Suppl):Abstract nr 23.
Abstract 31: Impact of the COVID-19 Pandemic on Cancer Registry Operations in the Caribbean
Authors: Quesnel-Crooks Sarah , Hanisch Rachel , Soerjomataram Isabelle , Edwards Brenda , White Arica , Kohler Betsy , Chao Ann , Mery Les , Andall-Brereton Glennis 
Published: July 2021

Abstract
Purpose: Cancer registration is an integral part of national disease surveillance, and actions must be taken to maintain operation of such essential systems, even during concurrent public health emergencies. This abstract summaries the impact of the COVID-19 pandemic on operations of population-based cancer registries (PBCRs) in the Caribbean.
Methods: In May 2020, the International Agency for Research on Cancer (IARC) issued a worldwide survey to members of the International Association of Cancer Registries (IACR) to assess the impact of the COVID-19 pandemic on PBCRs. In November, the IARC Caribbean Hub renewed this call for responses from IACR members plus additional Caribbean PBCRs. The experience of ten of thirteen registries contacted is presented.
Results: Survey responses were received from PBCRs in the Bahamas, Barbados, Bermuda, Cuba, Dominican Republic, Guyana, Jamaica, Martinique, Puerto Rico, and Trinidad and Tobago. Five (50%) registries reported that the COVID-19 pandemic negatively affected operations. These same registries reported a reduction in data collection capacity ranging from 28% to 100%. Reasons for data collection disruptions included an inability to fully access physical data sources and a reduced capacity or inability to receive cancer notifications and files. Where data collection was impacted, all registries expected missing cancer cases to be registered later in the next 12-15 months. Remote working was one strategy implemented by unaffected registries. One (10%) registry reported an impact on registry financing, and two (20.0%) reported that staffing was affected.
Conclusions: Half of responding Caribbean registries reported having been negatively affected by the COVID-19 pandemic, particularly regarding data collection. Improved access to physical data sources for registration activities could mitigate continuing operational challenges in the current pandemic. Accelerating the development of electronic records and direct source abstraction via remote electronic access could support continuous operation of cancer registries amidst future emergencies or operational disruptions.
Citation Format: Sarah Quesnel-Crooks, Rachel Hanisch, Isabelle Soerjomataram, Brenda Edwards, Arica White, Betsy Kohler, Ann Chao, Les Mery, Glennis Andall-Brereton. Impact of the COVID-19 Pandemic on Cancer Registry Operations in the Caribbean [abstract]. In: Proceedings of the 9th Annual Symposium on Global Cancer Research; Global Cancer Research and Control: Looking Back and Charting a Path Forward; 2021 Mar 10-11. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2021;30(7 Suppl):Abstract nr 31.