bluuebunny/crossref_metadata_2025_split huggingface dataset:
АКТУАЛЬНІ ПИТАННЯ ПРИЗНАЧЕННЯ КРИМІНАЛІСТИЧНИХ СУДОВИХ ЕКСПЕРТИЗ В УКРАЇНІ
Authors: Лазебний А. М. , Божук І. І. 
Published: May 2021

У статті досліджено основні проблемні питання при призначенні та проведенні судової експертизи, що впивають на терміни та результати експертних досліджень, а також вирішення цих питань при розслідуванні у кримінальних провадженнях.
На підставі аналізу наукових домок та правової регламентації, розроблено авторське визначення терміну «судова експертиза». Проведено аналіз чинного кримінального процесуального законодавства України та визначено основні проблеми та колізійні моменти.
З урахуванням сучасних тенденцій розвитку судової експертології як науки виокремлено, що існує нагальна потреба в однозначному термінологічному визначенні понятійного апарату, встановлення правового статусу експерта та регламентації комплексної експертизи в кримінальному провадженні.
Аргументовано необхідність внесення змін до порядку та підстав проведення судової криміналістичної експертизи, з метою уникнення узурпації такого права слідчим суддею.
До основних проблем застосування чинних норм права віднесено, перш за все ст. 244 чинного КПК України, відповідно до якої «експерта може залучити слідчий суддя за клопотанням сторони захисту в разі відмови слідчого, прокурора в задоволенні клопотання сторони захисту про залучення експерта». Застосування цього положення тягне за собою ряд проблем, серед яких: санкціонування слідчим суддею процедури проведення судової експертизи є недоцільним, оскільки більшість експертиз у кримінальному провадженні є обов’язковими, а тому перекладання функції призначення і так обов’язкових експертиз на суд лише затягне процес розгляду справи; за таких обставин не можливо забезпечити оптимізацію судових витрат на проведення судових експертиз; це спричиняє дисбаланс сторін кримінального провадження, що тягне за собою неефективність способів захисту та правосуддя в цілому, а також протирічать засаді свободи в поданні сторонами до суду своїх доказів та доведенні їх переконливості; це веде до невиправданих формальних i неформальних обмежень у використанні засобiв доказування та нівелювання принципу змагальностi сторiн кримінального процесу.
Запропоновано вирішити проблемні аспекти термінологічного апарату, визначення статусу експерта та комплексної експертизи, а також порядку на підстав проведення судової експертизи у кримінальному провадженні у новому проекті Закону України «Про судово-експертну діяльність».
Ключові слова: експерт, суд, кримінальне провадження, досудове розслідування, слідчий суддя, слідчий, суддя, реформи, правосуддя.
Addressing distress management challenges: Recommendations from the consensus panel of the American Psychosocial Oncology Society and the Association of Oncology Social Work
Authors: Deshields Teresa L. , Wells‐Di Gregorio Sharla , Flowers Stacy R. , Irwin Kelly E. , Nipp Ryan , Padgett Lynne , Zebrack Brad 
Published: May 2021

AbstractDistress management (DM) (screening and response) is an essential component of cancer care across the treatment trajectory. Effective DM has many benefits, including improving patients' quality of life; reducing distress, anxiety, and depression; contributing to medical cost offsets; and reducing emergency department visits and hospitalizations. Unfortunately, many distressed patients do not receive needed services. There are several multilevel barriers that represent key challenges to DM and affect its implementation. The Consolidated Framework for Implementation Research was used as an organizational structure to outline the barriers and facilitators to implementation of DM, including: 1) individual characteristics (individual patient characteristics with a focus on groups who may face unique barriers to distress screening and linkage to services), 2) intervention (unique aspects of DM intervention, including specific challenges in screening and psychosocial intervention, with recommendations for resolving these challenges), 3) processes for implementation of DM (modality and timing of screening, the challenge of triage for urgent needs, and incorporation of patient‐reported outcomes and quality measures), 4) organization—inner setting (the context of the clinic, hospital, or health care system); and 5) organization—outer setting (including reimbursement strategies and health‐care policy). Specific recommendations for evidence‐based strategies and interventions for each of the domains of the Consolidated Framework for Implementation Research are also included to address barriers and challenges.
Study of glycemic status and lipid profile in type 2 diabetic patients attending the Community Based Medical College Hospital
Authors: Rahman Md Muzibar , Hassan Zahid , Sen Bina , Shahidullah ASM , Paul Arup Ratan , Saha Kamana Rani 
Published: May 2021

A cross sectional study of 129 type 2 diabetic patients attending out patient department of Community Based Medical College Hospital was done with an aim to evaluate their metabolic control. Of the total cases, 88 (68.2%) were male and 41 (31.8%) were female. Blood glucose and lipid levels were measured by following the standard laboratory methods. The study subjects had relatively poor glycemic control. Fasting serum glucose was 7.45±2.71 (mmol/l, mean±SD); Male-7.04±2.36 and Female 8.33±3.20, p=ns'. Mean (±SD) of total cholesterol and triglyceride of the female subjects were significantly higher compared to the male counterpart (p=0.01 for both). About 71% and 78.0% female subjects had triglyceride and HDLc abnormality compared to 63.3% and 61.4% respectively in their male counterpart. Fasting glucose level showed significant positive correlation with triglyceride among total and male study subjects (p=0.003 for both). In case of total cholesterol significant positive association was among total and female subjects (p=0.005 and 0.007 respectively). The data concluded that (i) relatively large number of diabetic patients were having dyslipidemia of either component or in combination; and (ii) attention needs to be paid to address this issue of dyslipidemia and to avoid or at least delay the coronary artery and atherosclerotic complications of these subjects.
CBMJ 2014 January: Vol. 03 No. 01 P: 20-24
Fetal Outcome in Premature Rupture of Membrane - A Study Done in the Tertiary Level Specialized Hospital in Bangladesh
Authors: Adhikary Sanchita , Tanira Shaorin , Sultana Arifa , Wazed Feroza , Chowdhury Saleha Begum 
Published: May 2021

A descriptive cross-sectional study was done in the Department of Obstetrics and Gynaecology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, from February to July of 2008, on 50 pregnant women with more than 28 weeks of pregnancy both primigravid and multigravid with rupture of membranes prior to labor, to find out the effect of premature rupture of membrane on fetal outcome. 48 live births were observed and there were 2 fetal loss. Among those newborns, 28 (58.33%) were male and 20 (41.66%) were female. 54.16% of babies had APGAR score at 5 minutes after birth was >7 and those needed no treatment. APGAR score was 7 in 45.82% babies; all of them were treated and cured. Among the newborns, 52.08% babies had birth weight > 2500 gm, 45.83% had their birth weight in between 1500 and 2500 gm, while 1 (2.08%) was between 1000 and 1500 gm. However, 22 (45.83%) were affected by the consequences of PROM and birth process. Among them, 36.36% developed jaundice, 29.27% suffered from birth asphyxia, and RTI and neonatal sepsis were evident in 18.18% each. 15% babies were treated conservatively and 7% babies were treated in the neonatal ward being admitted into it. There was no neonatal loss.
CBMJ 2014 January: Vol. 03 No. 01 P: 25-28
Knowledge on mode of transmission and prevention of HIV/AIDS among the floating sex workers in some selected areas of Dhaka City
Authors: Nahar Lutfun , Mahejabin Farzana , Parveen Shamima 
Published: May 2021

Knowledge on sexually transmitted disease like HIV/AIDS can affect and help in reducing the incidence and number of cases of the disease in the community. The present study makes an attempt to assess the knowledge on mode of transmission and prevention of HIV/AIDS among the floating sex workers in some selected areas of Dhaka city. A descriptive type of cross-sectional study was conducted for a period of six months from January to June 2009, in Drop in centers in some selected areas of Dhaka city. Data were collected from 90 floating sex workers to find their knowledge about HIV/AIDS. Of the 90 respondents, 88 (97.8%) respondents had heard of HIV/AIDS. Majority of them (52, 57.9%) were got knowledge on HIV/AIDS from NGO workers followed by 13 (14.4%) from radio and 12(13.3%) from television. Most of the respondents (74, 82.2%) knew that HIV could be transmitted by unsafe sex with a known case of AIDS. Regarding prevention of HIV/AIDS, 73(81.1%) respondents knew that use of condom was a way of prevention of AIDS. Majority (51, 56.7%) scored average knowledge on transmission and prevention of HIV/AIDS. Government and non-government organizations and media can play effective role to make people aware of HIV/AIDS particularly the high risk groups.
CBMJ 2014 January: Vol. 03 No. 01 P: 41-45
Novel Pyran-Linked Phthalazinone-Pyrazole Hybrids: Synthesis, Cytotoxicity Evaluation, Molecular Modeling, and Descriptor Studies
Authors: Malik M. Shaheer , Asghar Basim H. , Syed Riyaz , Alsantali Reem I. , Morad Moataz , Altass Hatem M. , Moussa Ziad , Althagafi Ismail I. , Jassas Rabab S. , Ahmed Saleh A. 
Published: May 2021

A series of novel pyran-linked phthalazinone-pyrazole hybrids were designed and synthesized by a facile one-pot three-component reaction employing substituted phthalazinone, 1H-pyrazole-5-carbaldehyde, and active methylene compounds. Optimization studies led to the identification of L-proline and ethanol as efficient catalyst and solvent, respectively. This was followed by evaluation of anticancer activity against solid tumor cell lines of lung and cervical carcinoma that displayed IC50 values in the range of 9.8–41.6 µM. Molecular modeling studies were performed, and crucial interactions with the target protein were identified. The drug likeliness nature of the compounds and molecular descriptors such as molecular flexibility, complexity, and shape index were also calculated to understand the potential of the synthesized molecules to act as lead-like molecule upon further detailed biological investigations as well as 3D-QSAR studies.
Chemical Composition, Antimicrobial and Insecticidal Activities of Essential Oils of Discarded Perfume Lemon and Leaves (Citrus Limon (L.) Burm. F.) as Possible Sources of Functional Botanical Agents
Authors: Wu Panpan , Tang Xiaowen , Jian Rongchao , Li Jiahao , Lin Maoyu , Dai Huachao , Wang Kangpeng , Sheng Zhaojun , Chen Baizhong , Xu Xuetao , Li Chen , Lin Zhongze , Zhang Qingmin , Zheng Xi , Zhang Kun , Li Dongli , Hong Weiqian David 
Published: May 2021

Two essential oils were isolated from discarded perfume lemon and leaves (Citrus limon (L.) Burm. F.) by hydro-distillation with good yield (0.044% for perfume lemon and 0.338% for leaves). Their biological activities were evaluated against five selected bacterial strains and Aedes albopictus (Ae. albopictus, Diptera: Culicidae). Chemical composition indicated that both essential oils were rich in essential phytochemicals including hydrocarbons, monoterpenes and sesquiterpene. These constituents revealed some variability among the oils displaying interesting chemotypes (R)-(+)-limonene (12.29–49.63%), citronellal (5.37–78.70%) and citronellol (2.98–7.18%). The biological assessments proved that the two essential oils had similar effect against bacterial (inhibition zones diameter ranging from 7.27 ± 0.06 to 10.37 ± 0.15 mm; MICs and MBCs ranging from 1.6 to 6.4 mg/mL); against Ae. albopictus larvae (LC50 ranging from 384.81 to 395.09 ppm) and adult mosquito (LD50 ranging from 133.059 to 218.962 μg/cm2); the activity of the two chemotypes ((R)-(+)-limonene and citronellal): larvae (LC50 ranging from 267.08 to 295.28 ppm), which were all presented in dose-dependent manners. Through this work, we have showcased that recycling and reusing of agriculture by-products, such as discarded perfume lemon and leaves can produce eco-friendly alternatives in bacterial disinfectants and mosquito control product.
Serum Uric Acid Revealed a U-Shaped Relationship With All-Cause Mortality and Cardiovascular Mortality in High Atherosclerosis Risk Patients: The ASSURE Study
Authors: Cang Yan , Xu Shaojie , Zhang Jingyin , Ju Jingyi , Chen Zijun , Wang Keke , Li Jue , Xu Yawei 
Published: May 2021

Background: Previous studies have demonstrated an association between hyperuricemia and cardiovascular disease (CVD). The Framingham study confirmed that patients with high atherosclerotic risks (HARs) had worse prognoses. However, after adjusting for confounding factors, the association between serum uric acid (SUA) and all-cause mortality and cardiovascular mortality remains unclear, especially for HAR patients.Objective: The aim of this study was to reveal the relationship of SUA with all-cause and cardiovascular mortality in HAR patients.Methods: This multicenter cohort study enrolled 3,047 participants, and the follow-up was 68.85 ± 11.37 months. Factors related to cardiovascular and all-cause mortality were tested by multivariate Cox regression analysis. Restricted cubic splines (RCSs) with knots were used to explore the shape of the dose–response relationship with SUA and the hazard ratio (HR) of all-cause and CVD mortality. SUA transformed by RCS was added to the Cox regression model as an independent variable, and all-cause and CVD mortality scores were calculated. Survival receiver operating characteristic curves were produced using a regression model predicting the score.Results: SUA demonstrated a “U-shaped” relationship with all-cause and cardiovascular mortality. SUA predicted all-cause and CVD mortality, with cutoff values of values of &gt;370.5 μmol/L for males and &gt;327.65 μmol/L for females and &lt;180.5 μmol/L for males and &lt;165.7 μmol/L for females, respectively. The survival ROC curve indicated that SUA is able to predict all-cause and CVD mortality, with areas under the curve of 0.702 and 0.711, respectively. The HRs of all-cause mortality (male and female) with hyperuricemia and hypouricemia were 2.08 and 2.01 and 2.04 and 1.98, respectively, and the HRs of CVD mortality (male and female) were 2.09 and 1.79, and 2.02 and 1.89, respectively.Conclusion: Abnormal SUA levels were significant and independent risk factors for all-cause and CVD mortality. Hyperuricemia and hypouricemia increased mortality in both males and females. Routine SUA evaluation and intensive management are needed for HAR patients.Clinical Trial Registration:www.ClinicalTrials.gov, identifier: NCT03616769.
Novel Urinary Glycan Biomarkers Predict Cardiovascular Events in Patients With Type 2 Diabetes: A Multicenter Prospective Study With 5-Year Follow Up (U-CARE Study 2)
Authors: Mise Koki , Imamura Mariko , Yamaguchi Satoshi , Watanabe Mayu , Higuchi Chigusa , Katayama Akihiro , Miyamoto Satoshi , Uchida Haruhito A. , Nakatsuka Atsuko , Eguchi Jun , Hida Kazuyuki , Nakato Tatsuaki , Tone Atsuhito , Teshigawara Sanae , Matsuoka Takashi , Kamei Shinji , Murakami Kazutoshi , Shimizu Ikki , Miyashita Katsuhiro , Ando Shinichiro , Nunoue Tomokazu , Yoshida Michihiro , Yamada Masao , Shikata Kenichi , Wada Jun 
Published: May 2021

Background: Although various biomarkers predict cardiovascular event (CVE) in patients with diabetes, the relationship of urinary glycan profile with CVE in patients with diabetes remains unclear.Methods: Among 680 patients with type 2 diabetes, we examined the baseline urinary glycan signals binding to 45 lectins with different specificities. Primary outcome was defined as CVE including cardiovascular disease, stroke, and peripheral arterial disease.Results: During approximately a 5-year follow-up period, 62 patients reached the endpoint. Cox proportional hazards analysis revealed that urinary glycan signals binding to two lectins were significantly associated with the outcome after adjustment for known indicators of CVE and for false discovery rate, as well as increased model fitness. Hazard ratios for these lectins (+1 SD for the glycan index) were UDA (recognizing glycan: mixture of Man5 to Man9): 1.78 (95% CI: 1.24–2.55, P = 0.002) and Calsepa [High-Man (Man2–6)]: 1.56 (1.19–2.04, P = 0.001). Common glycan binding to these lectins was high-mannose type of N-glycans. Moreover, adding glycan index for UDA to a model including known confounders improved the outcome prediction [Difference of Harrel's C-index: 0.028 (95% CI: 0.001–0.055, P = 0.044), net reclassification improvement at 5-year risk increased by 0.368 (0.045–0.692, P = 0.026), and the Akaike information criterion and Bayesian information criterion decreased from 725.7 to 716.5, and 761.8 to 757.2, respectively].Conclusion: The urinary excretion of high-mannose glycan may be a valuable biomarker for improving prediction of CVE in patients with type 2 diabetes, and provides the rationale to explore the mechanism underlying abnormal N-glycosylation occurring in patients with diabetes at higher risk of CVE.Trial Registration: This study was registered with the University Hospital Medical Information Network on June 26, 2012 (Clinical trial number: UMIN000011525, URL: https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000013482).
Left Bundle Branch Area Pacing vs. Biventricular Pacing for Cardiac Resynchronization Therapy: A Meta-Analysis
Authors: Liu Jiyi , Sun Fengzhi , Wang Zefeng , Sun Jiao , Jiang Xue , Zhao Weilong , Zhang Zhipeng , Liu Lu , Zhang Shulong 
Published: May 2021

Background: Left bundle branch area pacing (LBBAP) is a recently proposed method for conduction system pacing. We performed a meta-analysis of controlled studies to compare the clinical outcome in patients who received LBBAP vs. biventricular pacing (BVP) for cardiac resynchronization therapy (CRT).Methods: PubMed, Embase, and Cochrane's Library databases were searched for relevant controlled studies. A random-effect model incorporating the potential heterogeneity was used to synthesize the results.Results: Four non-randomized controlled studies including 249 patients with heart failure (HF) for CRT were included, and the patients were followed for 6–12 months. Compared with BVP, LBBAP was associated with significantly shortened QRS duration [mean difference (MD): −29.18 ms, 95% confidence interval (CI): −33.55–24.80, I2 = 0%, P &lt; 0.001], improved left ventricular ejection fraction (MD: 6.93%, 95% CI: 4.69–9.17, I2 = 0%, P &lt; 0.001), reduced left ventricular end-diastolic dimension (MD: −2.96 mm, 95% CI: −5.48 to −0.44, I2 = 0%, P = 0.02), and improved New York Heart Association class (MD: −0.54, 95% CI: −0.84 to −0.24, I2 = 65%, P &lt; 0.001). Moreover, patients who received LBBAP were more likely to achieve echocardiographic [odds ratio (OR): 5.04, 95% CI: 2.17–11.69, I2 = 0%, P &lt; 0.001] and clinical (OR: 7.33, 95% CI: 1.62–33.16, I2 = 0%, P = 0.01) CRT responses.Conclusion: Current evidence from non-randomized studies suggests that LBBAP appears to be a promising method for CRT, which is associated with more remarkable improvements of symptoms and cardiac function in HF patients with indication for CRT.
Disparities in Peripheral Artery Disease Hospitalizations Identified Among Understudied Race-Ethnicity Groups
Authors: Chen LaiTe , Zhang Donglan , Shi Lu , Kalbaugh Corey A. 
Published: May 2021

Background: To assess racial/ethnic differences in disease severity, hospital outcomes, length of stay and healthcare costs among hospitalized patients with peripheral artery disease (PAD).Methods: This study used data from the National Inpatient Sample (NIS) to explore the racial/ethnic disparities in PAD-related hospitalizations including presence of PAD with chronic limb threatened ischemia (CLI), amputation, in-hospital mortality, length of hospital stays and estimated medical costs. Race-ethnicity groups included non-Hispanic White, Black, Hispanic, Asian or Pacific Islander, Native American, and others (multiple races). Regression analyses adjusted for age, gender, Charlson Comorbidity Index, primary payer, patient location, bed size of the admission hospital, geographic region of the hospital, and rural/urban location of the hospital.Results: A total of 341,480 PAD hospitalizations were identified. Compared with non-Hispanic Whites, Native Americans had the highest odds of PAD with CLI (OR = 1.77, 95% CI: 1.61, 1.95); Black (OR = 1.71, 95% CI: 1.66, 1.76) and Hispanic (OR = 1.36, 95% CI: 1.31,1.41) patients had higher odds of amputation; Asian or Pacific Islanders had a higher mortality (OR = 1.20, 95% CI: 1.01,1.43), whereas Black (OR = 0.81, 95% CI: 0.76, 0.87) patients has a lower mortality; Asian or Pacific Islanders incurred higher overall inpatient costs (Margin = 30093.01, 95% CI: 28827.55, 31358.48) and most prolonged length of stay (IRR = 0.14, 95% CI: 0.09, 0.18).Conclusions: Our study identified elevated odds of amputation among Hispanic patients hospitalized with PAD as well as higher hospital mortality and medical expenses among Asian or Pacific Islander PAD inpatients. These two demographic groups were previously thought to have a lower risk for PAD and represent important populations for further investigation.
Shifting Prevalence Patterns for Special Educational Needs in the Era of Response-to-Intervention Policy
Authors: Hall-Mills Shannon 
Published: May 2021

In the United States, the Response to Intervention framework provides tiered levels of support in general education (kindergarten through grade 12) to improve student outcomes and may relate to special education determinations. While broadly applied to eligibility determinations for children with specific learning disability, the Response to Intervention model also presents an interesting consideration for children with language impairment. The requirement of the Response to Intervention framework in education policy may have a significant impact on the identification and eligibility processes for children with special educational needs. The aim of the present study was to explore whether this policy implementation altered the prevalence of students with disabilities ages 3–21 years who were determined to be eligible for special education under the categories of specific learning disability and language impairment. Longitudinal data was examined to determine whether significant changes occurred in the prevalence rates in a state that mandated implementation of Response to Intervention policy. The results revealed that significant changes occurred in the prevalence rates from pre-to post implementation of Response to Intervention policy; language impairment prevalence increased and specific learning disability prevalence decreased. Prevalence changes have maintained over multiple subsequent school years. The findings have important implications for policy and practices focused on the identification of these common disabilities throughout the school years.