bluuebunny/crossref_metadata_2025_split huggingface dataset:
Robotic Nerve Sheath Tumor Resection With Intraoperative Neuromonitoring: Case Series and Systematic Review
Authors: Curry Brian P. , Alvarez Reinier , Widemann Brigitte C. , Johnson Matthew , Agarwal Piyush K. , Lehky Tanya , Valera Vladimir , Chittiboina Prashant 
Published: December 2021

BACKGROUND:
Retroperitoneal nerve sheath tumors present a surgical challenge. Despite potential advantages, robotic surgery for these tumors has been limited. Identifying and sparing functional nerve fascicles during resection can be difficult, increasing the risk of neurological morbidity.

OBJECTIVE:
To review the literature regarding robotic resection of retroperitoneal nerve sheath tumors and retrospectively analyze our experience with robotic resection of these tumors using a manual electromyographic probe to identify and preserve functional nerve fascicles.

METHODS:
We retrospectively analyzed the clinical courses of 3 patients with retroperitoneal tumors treated at the National Institutes of Health by a multidisciplinary team using the da Vinci Xi system. Parent motor nerve fascicles were identified intraoperatively with a bipolar neurostimulation probe inserted through a manual port, permitting tumor resection with motor fascicle preservation.

RESULTS:
Two patients with neurofibromatosis type 1 underwent surgery for retroperitoneal neurofibromas located within the iliopsoas muscle, and 1 patient underwent surgery for a pelvic sporadic schwannoma. All tumors were successfully resected, with no complications or postoperative neurological deficits. Preoperative symptoms were improved or resolved in all patients.

CONCLUSION:
Resection of retroperitoneal nerve sheath tumors confers an excellent prognosis, although their deep location and proximity to vital structures present unique challenges. Robotic surgery with intraoperative neurostimulation mapping is safe and effective for marginal resection of histologically benign or atypical retroperitoneal nerve sheath tumors, providing excellent visibility, increased dexterity and precision, and reduced risk of neurological morbidity.
Trauma education and training for healthcare providers: a scoping review
Authors: Alshamrani Abdullah , Alshammari Talal , Williams Brett 
Published: December 2021

Background:Every six seconds, someone in the world dies because of injury. Trauma is a major public health problem and leads to significant mortality and morbidity worldwide. Healthcare provider training can affect patient outcomes; therefore, it is useful to examine the efficacy of trauma training programmes. This scoping review aimed to determine the impact of trauma training or education on healthcare providers' confidence.Method:Ovid MEDLINE, Ovid Embase, Ovid Emcare, CINAHL, Scopus, Google Scholar and Trove were systematically searched on 7 August 2021, and a methodology adopted to ensure the scoping review was comprehensive.Results:A total of 749 articles were retrieved, of which 15 were eligible for the scoping review. After the articles were analysed, two themes—knowledge and experience—were identified. Knowledge improved from attending courses. However, knowledge retention fell over time. Participants reported that their confidence improved after attending courses, but an inverted correlation was observed between experience and knowledge.Conclusion:Trauma training courses improve the confidence of healthcare providers. However, these courses should be conducted regularly and trainees observed to assess their confidence. Further studies should be conducted to evaluate the effect of these courses on practitioner confidence.
Comparison of statistical and analytical hierarchy process methods on flood susceptibility mapping: In a case study of the Lake Tana sub-basin in northwestern Ethiopia
Authors: Wubalem Azemeraw , Tesfaw Gashaw , Dawit Zerihun , Getahun Belete , Mekuria Tamrat , Jothimani Muralitharan 
Published: December 2021

Abstract
The flood is one of the frequently occurring natural hazards within the sub-basin of Lake Tana. The flood hazard within the sub-basin of Lake Tana causes damage to cropland, properties, and a fatality every season. Therefore, flood susceptibility modeling in this area is significant for hazard reduction and management purposes. Thus, the analytical hierarchy process (AHP), bivariate (information value [IV] and frequency ratio [FR]), and multivariate (logistic regression [LR]) statistical methods were applied. Using an intensive field survey, historical document, and Google Earth Imagery, 1,404-flood locations were determined, classified into 70% training datasets and 30% testing flood datasets using a subset within the geographic information system (GIS) environment. The statistical relationship between the probability of flood occurrence and 11 flood-driving factors was performed using the GIS tool. The flood susceptibility maps of the study area were developed by summing all weighted aspects using a raster calculator. It is classified into very low, low, moderate, high, and very high susceptibility classes using the natural breaks method. The accuracy and performance of the models were evaluated using the area under the curve (AUC). As the result indicated, the FR model has better performance (AUC = 99.1%) compared to the AHP model (AUC = 86.9%), LR model (AUC = 81.4%), and IV model (AUC = 78.2%). This research finds out that the applied methods are quite worthy for flood susceptibility modeling within the study area. In flood susceptibility modeling, method selection is not a serious challenge; the care should tend to the input parameter quality. Based on the AUC values, the FR model is comparatively better, followed by the AHP model for regional land use planning, flood hazard mitigation, and prevention purposes.
Synergistic effects of halloysite nanotubes with metal and phosphorus additives on the optimal design of eco-friendly sandwich panels with maximum flame resistance and minimum weight
Authors: Kamarian Saeed , Yu Ruiwen , Song Jung-il 
Published: December 2021

Abstract
The present work addresses the optimal design of sandwich panels made of flax fabric (FF)/vinyl ester (VE) composite face sheets and honeycomb VE core. The sandwich structures are first optimized in terms of flammability by obtaining the best combination of ammonium polyphosphate (APP), halloysite nanotube (HNT), and magnesium hydroxide (MH) as three flame retardants (FRs). Using the Taguchi method and horizontal burning test, it is shown that [6, 3, and 3%] and [1, 0.5, and 0%] are the optimal combinations of APP, HNT, and MH for the face sheets and core, respectively. Cone calorimeter test results indicate that the optimal FR combinations significantly decrease the mass lost rate (MLR), heat rate release (HRR), total smoke release (TSR), and maximum average release heat emission (MARHE). The FR sandwich structures are then geometrically optimized under compressive loads based on their weight. Different failure modes are considered as the design constraints of the optimization problem. Imperialist competitive algorithm (ICA), as a powerful meta-heuristic algorithm, is implemented to considerably reduce the computational cost of the optimization process. The results of this study show that proper combinations of FR additives can increase the flame retardancy while decreasing the weight of sandwich panels.
N/S co-doped CoSe/C nanocubes as anode materials for Li-ion batteries
Authors: Cui Lifeng , Qi Haoyu , Wang Nannan , Gao Xin , Song Chunyu , Yang Jinghua , Wang Gang , Kang Shifeng , Chen Xiaodong 
Published: December 2021

Abstract
The transition metal selenide can be used as a potential material for the negative electrode of lithium-ion batteries (LIBs) owing to its high density and conductivity. Unfortunately, a large volume change occurs in the transition metal selenide during the charging and discharging process, which eventually results in the poor rate performance and rapid capacity decay. In response to this, the N/S co-doped CoSe nanocubes (CoSe/C–NS) can be fabricated where the S-doped cobalt 2-methylimidazole (ZIF-67) as both sacrifice template and cobalt source to directly mix with selenium powder and followed by the annealing process. In the process, the carbon frameworks derived from ZIF-67 can establish a coating layer to protect the structure of materials, and simultaneously the N/S co-doping can enhance the conductivity and broaden the interlayer of frameworks. These can further accelerate the storage capacity and the Li+ insertion and deintercalation process. As a negative electrode material of LIBs, the CoSe/C–NS delivers the high capacity, high rate performance, and long-term cycle stability. This protocol opens up an approvable approach to fabricate efficient anode materials with persistent electrochemical stability in LIBs.
INOVASI PEMBUATAN PIE SUSU SUBSTITUSI TEPUNG BONGGOL PISANG KEPOK (MUSA ACUMINATE L.)
Authors: Hidayah, Meddiati Fajri Putri Nurul 
Published: December 2021

ABSTRAK : Penelitian ini bertujuan 1) mengetahui tingkat kesukaan masyarakat terhadap produk pie susu substitusi tepung bonggol pisang kepok pada indikator warna,tekstur, aroma, dan rasa. 2) mengetahui kadar serat pangan pada pie pie susu substitusi tepung bonggol pisang kepok. Variabel bebas pada penelitian ini yaitu substitusi tepung bonggol pisang kepok dengan persentase yang berbeda yaitu 5%, 10% dan 15%. Metode pengumpulan data menggunakan penelitian uji kesukaan. Desain eksperimen menggunakan metode true eksperiment. Metode analisis yang digunakan adalah analisis deskriptif presentase dan untuk analisis kadar serat pangan menggunakan metode multienzim (AOAC, 1995). Hasil penelitian 1) Tingkat kesukaan masyarakat pada produk pie susu substitusi tepung bonggol pisang kepok pada sampel A yaitu menunjukan kriteria suka 81%, pada sampel B yaitu menunjukan kriteria suka 74%, dan sampel C yaitu menunjukan kriteria suka 72%. 2) kandungan kadar serat pangan pada pie susu substitusi tepung bonggol pisang kepok nilai rerata pada sampel A yaitu 12,60%, pada sampel B yaitu 15,32% dan pada sampel C yaitu 17,12%.Kata Kunci : Pie susu substitusi tepung bonggol pisang kepok, seratABSTRACT: The purposes of this research are 1) to determine the level of society favorite towards the product of milk pie of kepok banana hump flour on the indicator of color,Â texture, aroma, and flavor. 2) to determine the level of dietary fiber on the milk pie of kepok banana hump flour. Independent variable in this research is kepok banana hump flour with different percentage that are 5%, 10%, and 15%. Data collecting methode using preference test research. Experiment design using true experiment methode. Analysis methode that used was descriptive percentage analysis and to analyze the level dietary fiber using multienzim methode (AOAC, 1995). The results of research 1) The level of society favorite on the milk pie product of kepok banana hump flour on sample A showed like criteria 81%, on sample 2 showed like criteria 74%, and sample C showed like criteria 72%. 2) Dietary fiber content on milk pie of kepok banana hump flour mean value on sample A that is 12,60%, on sample B that is 15,32% and on sample C that is 17,12%.Keywords: Milk pie of kepok banana hump flour, fiber
Penerapan Embellishment pada Inovasi Busana Etnik Nusa Tenggara Timur dengan Inspirasi Burung Garugiwa
Authors: Nursyifa Sarah Rizki , Nurlita Asri Andarini 
Published: December 2021

Burung dengan nama latinÂ Pachycephala NudigulaÂ atau burung GarugiwaÂ merupakan satwa endemik yang menghuni kawasan Taman Nasional Kelimutu,Â Kabupaten Ende,Â Provinsi Nusa Tenggara Timur. Ciri khas burung Garugiwa, yaitu memiliki suara yang sangat nyaring, termasuk ke dalam jenis burung cerdas karena mampu menirukan suara dari lingkungan sekitarnyaÂ dan terkenal dengan keragaman kicauannya yang tersusun dari 12 nada yang berbeda. Keunikan burung garugiwa menjadi inspirasi bentuk dan hiasan dekoratif dalam penerapan embellishment pada inovasi busana etnik untuk kesempatan pesta. Embellishment merupakan ornamen untuk menghias permukaan tekstil dengan berbagai macam teknik misalnya: penambahan warna, pola, tekstur atau desain ke kain melalui penggunaan media luar. Salah satu penerapan embellishment yang banyak digunakan adalah lekapan bordir dan payet. Teknik tersebut banyak dipilih sebagai penambah aksen dekoratif terutama pada busana pesta. Busana pesta termasuk ke dalam houte couture, yaitu busana berkualitas tinggi dengan Â eksklusivitas pada bahan, desain, dan kriteria pengerjan. Metode yang digunakan yaitu Project Based Learning dengan hasil penelitian terdapat beberapa faktor yang harus diperhatikan seperti: pemilihan bentuk atau motif, ukuran, dan warna agar hasilnya lebih maksimal
Activities Online and Compulsive Internet Use in Primary School-Aged Children: Whether and How it Has Changed during the COVID-19 Pandemic?
Authors: Jusienė Roma , Breidokienė Rima , Laurinaitytė Ilona , Pakalniškienė Vilmantė 
Published: December 2021

There has been a growing concern among researchers about the use of various information technologies with screens and the Internet by children and adolescents over the past decade. Researchers are concerned that such type of activities can have negative consequences for mental health. Recent studies reveal that Internet use and screen time increased due to the quarantine restrictions, lockdowns and therefore distance education during the COVID-19 pandemic. This study aims: 1) based on parental reports, to find out the changes in screen time, the online activities and the compulsive Internet use (CIU) of 10-11 years old children during the quarantine due to the COVID-19 pandemic; 2) to determine the links between children’s CIU and the screen time, online activities, children’s gender and their parents’ education. The results of this study showed that screen time was longer and children’s CIU scores were significantly higher in Spring 2020 if to compare to Autumn 2019. Boys were reported to have higher CIU scores than girls. Children’s CIU was significantly predicted by overall screen time and online activities for entertainment, especially when during quarantine.
Spinal Muscular Atrophy 5q under the Mask of Myopathy: 10 Clinical Cases
Authors: Kurbatov Sergei A. 
Published: December 2021

Background. Spinal muscular atrophy 5q (5q SMA) is the most frequent autosomal recessive hereditary neuromuscular disease. Molecular genetic testing is used for SMA diagnosis, and it can confirm only 5q SMA. The clinical findings and results of paraclinical studies may overlap with hereditary primary-muscular diseases making the diagnosis difficult and delaying the administration of pathogenetic treatment for 5q SMA.Clinical case description. Clinical description of 10 patients with 5q SMA aged from 3 months to 25 years with different severity of proximal tetraparesis, skeletal muscular atrophy and tendon reflexes depression is given. 3 patients under 2 years of age with myogenic pattern at needle electromyography (nEMG) in lateral vastus muscle and 7 patients over 2 years of age with increased levels of creatine phosphokinase (CPK) in blood serum were mistakenly diagnosed for inherited primary-muscular diseases for the period from 1 month to 12 years. After the genetic counselling based on the disease course and clinical findings we suspected and later confirmed 5q SMA.Conclusion. In case of flaccid proximal tetraparesis associated with myogenic pattern at nEMG in young children or with increased CPK levels at late manifestation it is crucial to perform differential diagnosis of 5q SMA since there are options of pathogenetic therapy.
RESEARCHES CONCERNING THE CAPACITY OF SOME MACROMYCETES SPECIES FOR ACCUMULATING HEAVY AND RARE METALS
Authors: Busuioc Gabriela , Stihi Claudia , Dumitru M. 
Published: December 2021

It is necessary today to increase in Romania also the efforts to research in direction of identifying those biosystems which are hyperaccumulators for heavy and rare metals in order to be used as instruments in environmental clean biotechnologies as well as bioindicators or metal sources. In USA and Australia the researches in this way are extended over all common species of mushrooms (macromycetes).
That is the reason we determinated the chemical content in metals of some macromycetes (mushrooms) species
which are autochthonous in forestry ecosystems of Dambovita county. We begun a large study in this aria, but in
this paper we present a study about two species very common in our forestry ecosystems - Armillariella mellea
and Macrolepiota procera. In the same time we made the analyses of soil elemental content under macromycetes
studied. The determinations were made by spectrometry advanced method in our own laboratories by ElvaX spectrometer. The resultes show a large elemental content in soil, but the content over 1ppm in bioelements, heavy and rare metals as number in two macromycetes species is a limited one. Everyone of two macromycetes species contains heavy metals (Fe, Cu, Zn) and rare metals (Re, Os).
THE COMPARATIVE BIOFUELS IMPACT ON THE ENVIRONMENT COMPARED WITH DIESEL OIL BY THE EFFECT ON Lolium perennial (Raigras) Seeds Germination
Authors: Ivan Ilarie , Mariasiu Florin 
Published: December 2021

In the present days, the needing of development the new classes of fuels is a real and immediate challenge for the humanity. These new classes of fuel must replace the fossil fuel in order to reduce the global pollution and to be friendly with the environment. The researches conducted until now in worldwide and also at the Biofuel Laboratory of Mechanic Faculty (under the supervision of prof. N. Burnete, Ph.D.) show that the biofuels based on vegetable oil can be an answer to the above mentioned issues. In addition, it is necessary to study the impact of this class of biofuels in time on the air and soil pollution, vegetable and animal products etc.
The present paper presents the experimental researches about the environmental impact of using the biofuels comparatively with fossil fuels (diesel oil). The research methodology was making in order to respect the actual standards to obtain more accurate and confident results. The basic conclusion of conducted experiments is that the using the biofuels in the internal combustion engines beside of diesel oil can be an important factor to reduce the pollution factors on environment.
Методологические аспекты определения оксимов стероидных гормонов методом УВЭЖХ-МСВР
Authors: Дмитриева Екатерина Владимировна , Темердашев Азамат Зауалевич , Азарян Алиса Андреевна 
Published: December 2021

Рассмотрены методологические аспекты применения дериватизации стероидных гормонов с использованием гидроксиламина для дальнейшего количественного анализа производных андрогенов, эстрогенов, прогестинов и глюкокортикоидов. Известно, что его использование позволяет значительно увеличить чувствительность масс-спектрометрического детектирования некоторых стероидных гормонов ввиду образования легко ионизирующихся оксимов стероидов, а реакция получения производных является простой.
Однако наряду с перечисленными достоинствами, при использовании данного способа происходит образование стереоизомеров, что приводит к расщеплению или полному разделению пиков дериватов на хроматограммах. Изменение программы градиентного элюирования не всегда позволяет получить один пик деривата без потери эффективности и селективности разделения остальных аналитов, присутствующих в пробе, что делает актуальным вопрос выбора «мишени» для анализа. Принимая во внимание наличие выраженных матричных эффектов при проведении определения стероидных гормонов и их производных в биологических жидкостях с использованием метода ВЭЖХ-МС(/МС) с электрораспылительной ионизацией, подобное поведение веществ при их хроматографическом разделении может быть использовано для повышения точности и надежности получаемых результатов благодаря интегрированию не всех пиков дериватов, а путем выбора одного, наименее подверженного матричным эффектам, обусловленным, например, коэлюированием компонентов пробы. Это связано с тем, что в процессе протекания реакции формирование их изоформ происходит воспроизводимо, с одинаковым выходом, независимо от концентраций и матрицы, в которой протекает процесс.
Приведены результаты определения некоторых оксимов стероидных гормонов, рассмотрены аспекты, влияющие на точность, воспроизводимость и чувствительность анализа на примере определения оксимов эстрона и 11α-гидроксипрогестерона в диапазоне концентраций от 2.5 до 1000 нг/см3. Идентификация производных и контроль полноты протекания реакции проводили с использованием стандартных образцов исследуемых соединений и масс-спектрометрии высокого разрешения. Показано, что данная процедура дериватизации позволяет добиться значительно большей чувствительности по сравнению с подходами, основывающимися на прямом определении стероидных гормонов с использованием ВЭЖХ-МС(/МС). В случае необходимости чувствительность может быть повышена путем применения методов предварительного концентрирования и очистки образцов.
Изучение in silico структурных особенностей липаз из различных продуцентов как потенциальных агентов для иммобилизации на заряженных и гидрофобных носителях
Authors: Богомолов Даниил Юрьевич , Сакибаев Фархат Адильжанович , Холявка Марина Геннадьевна , Артюхов Валерий Григорьевич , Селеменев Владимир Федорович 
Published: December 2021

Липаза – гидролитический фермент, получаемый из многих организмов, таких как животные, растения, грибы и бактерии. Она осуществляет расщепление триглицеридов до моноглицеридов и жирных кислот, при этом обладает широкой субстратной специфичностью. Липазы применяются в пищевой промышленности и других сферах человеческой деятельности. Характерная особенность многих липаз – явление поверхностной активации, обуславливающее свойственную им зависимость скорости каталитической реакции от концентрации и агрегатного состояния субстрата.
Доказано, что функционирование ферментов зависит от их структурных особенностей. Внутренние полости, туннели и поры являются неотъемлемыми компонентами нативной конформации белка. Они играют важную роль в транспорте субстрата, кофакторов и ионов к активному и регуляторным центрам фермента. Кроме того, их конфигурация может влиять на термостабильность энзимов, в связи с чем изучение вышеперечисленных структур является необходимым для понимания механизмов функционирования биокатализаторов. Также важным элементом структуры ферментов являются скопления заряженных и гидрофобных аминокислотных остатков на их поверхности. Данное свойство необходимо учитывать при планировании путей адсорбционной иммобилизации биокатализаторов на различных носителях для использования в промышленности и медицине.
В работе исследованы состав, локализация и конфигурация внутренних полостей, туннелей, пор, а также поверхностных скоплений заряженных и гидрофобных аминокислотных остатков в молекулах липаз из Rhizopus niveus (PDB ID: 1LGY), Rhizomucor miehei (PDB ID: 3TGL), Burkholderia cepacia (PDB ID: 1OIL), панкреатических липаз Homo sapiens (PDB ID: 1N8S) и Equus caballus (PDB ID: 1HPL). Для расчета параметров и визуализации данных структур использовались программы MOLE и Maestro. Показано наличие соответственно 2, 1, 5, 5 и 2 туннелей и отсутствие пор для данных ферментов; а также наличие по 6 внутренних полостей для липаз из R. niveus и E. caballus, 5 внутренних полостей для молекулы из R. miehei и по 2 внутренних полости для энзимов из B. cepacia и H. sapiens. Приведены аминокислотный состав и профили туннелей изучаемых липаз. Выявлено, что данные структуры не сообщаются друг с другом общими пустотами. Установлено преобладание гидрофобных аминокислотных остатков в большинстве туннелей данных ферментов. Изучены структура, локализация и состав скоплений заряженных и гидрофобных аминокислотных остатков на поверхностях макромолекул. Выявлено возможное влияние расположения данных скоплений на связывание липаз с носителем при их адсорбционной иммобилизации.