bluuebunny/crossref_metadata_2025_split huggingface dataset:
High Normal Thyrotropin (TSH) is Associated with Higher Needed Dose of Erythropoietin in Hemodialysis Patients
Authors: Elsalam Rady Ibrahim Ali Abd , Elhamid Elkhateeb Mervat Abd , Mohamed Mabrouk Maaly , Elsayed Esheba Noha 
Published: October 2021

Background: Recombinant human erythropoietin demonstrated an impressive ability to improve hematocrit, raising hematocrit of hemodialysis patients, eliminating the need for transfusions, and in patients with iron overload, decreased serum ferritin. Thyrotropin could affect hematopoiesis by binding to a functional thyrotropin receptor, which is found in both erythrocytes and some extrathyroidal tissues. The aim of this study was to evaluate the relationship of Thyrotropin level within normal reference range (in euthyroid state) on erythropoietin dose in end-stage renal disease patients on hemodialysis.
Methods: Prospective cross-sectional study was carried out at the hemodialysis units. It included 60 patients who had end-stage renal disease on hemodialysis. The selected patients were classified into 2 groups: Group A: included 30 end-stage renal disease patients on hemodialysis with Thyrotropin level (0.4-<2.5 miu/L) and Group B: included 30 end-stage renal disease patients on hemodialysis with Thyrotropin level (2.5-4.2 miu/L).
Results: the hemoglobin level and the hematocrit level showed a highly statistically significant difference between both groups. The needed Erythropiotin dosage was higher in group B than in group A with highly statistically significant difference. Weighted Erythropiotin dosage was calculated (weighted Erythropiotin=Erythropiotin dosage/weight) and the mean required dose was less than the required dose in group B and there was a highly statistically significant difference between the two groups. There was a significant negative correlation between the Thyrotropin level and hematocrit level and that leads us to conclude that the higher the Thyrotropin, the lower hematocrit will be and subsequently the higher Erythropiotin dose needed.
Conclusions: There is a relationship between Thyrotropin level even within normal reference range (in euthyroid state) on erythropoietin dose in end-stage renal disease patients on hemodialysis. In other words, the higher Thyrotropin level is, the more Erythropiotin dose needed. The required erythropoietin stimulating agent dose can be predicted by measuring Thyrotropin level.
Recovery of Nigerian Heavy Oil: Application of Steam Flooding
Authors: Evans Okoro Emmanuel , Onyekonwu Mike , Ajienka Joseph 
Published: October 2021

Aims: Nigeria has a lot of conventional and heavy oil resources. Although much of the conventional oil resources have been developed since independence, the heavy oil resources have remained underdeveloped due to low recovery based on primary production and consequently doubts about economic viability based on the current fiscal regime. This paper examines the application of Steam Flooding enhanced oil recovery (EOR) method to suitable Nigerian heavy oil reservoirs, seeks to develop a diagnostic model to predict the performance, evaluates the economics to determine the viability of the EOR method. The development of heavy oil will increase Nigeria’s oil reserves and production.
Study Design: Data was collected for two heavy oil reservoirs from two oil companies in Nigeria following a Non-disclosure Agreement (NDA).
Place and Duration of Study: Emerald Energy Institute, University of Port Harcourt Nigeria, 2016 - 2021.
Methodology: The screening criteria of commercially effective EOR methods were applied to select steam flooding for the studied reservoirs. Design of Experiment (DoE) was used to evaluate the reservoirs and operating parameters and to determine their optimum values, which were then used to predict the performance of the reservoirs. The economics of the steam flood technique endorsed for the reservoirs considered were also evaluated using Discounted Cash Flow Analysis (DCFA).
Results: These assessments confirmed that steam flooding technique was technically and economically viable for the heavy oil reservoirs considered. The steam flood was observed to have a good recovery efficiency of 24%, as against the waterflooding technique which had 13% OOIP and natural depletion of 9% for the offshore reservoir. For the onshore reservoir, the recovery efficiency was 20% for steam flood, and 4% for natural depletion. The economic analysis showed that even at a worst-case heavy oil price of US$15, the project was viable.
Conclusion: Steam flooding is viable, can be applied to develop heavy oil reservoirs in Nigeria that meet the screening criteria, and thus increase national oil reserve and production.
Recommendation: The fiscal policy should be adjusted, especially the petroleum profit tax from 85% to 50% as an incentive to operators and investors to embark on steam flooding and other EOR methods.
Stability-indicating RP-UPLC Method for Determination of Vildagliptin in Drug Substance and Its Tablet Dosage Form
Authors: Peluri Kalyani , Rajasekaran S. 
Published: October 2021

Aim: The foremost purpose of this research work is to diminish the analysis time and to establish cost effective method for estimation of Vildagliptin by RP-UPLC.
Study Design: UPLC based Quantification studies.
Place and Duration of Study: Department of Pharmacy, Bhagwant University, Ajmer, Rajasthan, Indiabetween June 2020 and August 2020.
Methodology: A simple, responsive and precised RP-UPLC method with good robustness was developed and validated as per ICH for the analysis of Vildagliptin in drug substance and separation of degradants generated by different forced degradation conditions. Productive separation of Vildagliptin was attained by the use of Luna C18 column (100x2.6mm and 1.6µm) with a mobile phase composition of 0.1% v/v Trifluoroacetic acid and Acetonitrile in 80:20 v/v, which was pumped with 0.5 ml/min flow rate. The eluted substances were examined with PDA detector at 239nm. Stressed degradation studies were performed with proposed method to determine the percentage degradation of Vildagliptin.
Results: The RT of Vildagliptin was observed at 1.56 min. The developed method was validated as per ICHQ2B and proved that the method was precise, sensitive, specific and accurate.The lowest concentration of limit of detection (0.05µg/ml) and limit of quantification(0.5µg/ml) of Vildagliptin make obvious about the sensitivity of the method. The correlation coefficient found to be 0.9997 for given range of linear concentrations. The calculated average percentage recoveries of Vildagliptin in spiked solutions were found to be in the range of 99.1-100.5. The calculated % RSD was determined to be less than 2. Determination of degradation of amount of Vildagliptin by forced degradation studies representing the stability indicating nature of the proposed method.
Conclusion: The developed method said to be highly sensitive, accurate, specific and robust, therefore this method has high probability to adopt in pharmaceutical industry for regular analysis of Vildagliptin.
Coupling Spin Defects in a Layered Material to Nanoscale Plasmonic Cavities
Authors: Mendelson Noah , Ritika Ritika , Kianinia Mehran , Scott John , Kim Sejeong , Fröch Johannes E. , Gazzana Camilla , Westerhausen Mika , Xiao Licheng , Mohajerani Seyed Sepehr , Strauf Stefan , Toth Milos , Aharonovich Igor , Xu Zai‐Quan 
Published: October 2021

AbstractSpin defects in hexagonal boron nitride, and specifically the negatively charged boron vacancy (VB‐) centers, are emerging candidates for quantum sensing. However, the VB‐ defects suffer from low quantum efficiency and, as a result, exhibit weak photoluminescence. In this work, a scalable approach is demonstrated to dramatically enhance the VB‐ emission by coupling to a plasmonic gap cavity. The plasmonic cavity is composed of a flat gold surface and a silver cube, with few‐layer hBN flakes positioned in between. Employing these plasmonic cavities, two orders of magnitude are extracted in photoluminescence enhancement associated with a corresponding twofold enhancement in optically detected magnetic resonance contrast. The work will be pivotal to progress in quantum sensing employing 2D materials, and in realization of nanophotonic devices with spin defects in hexagonal boron nitride.
Acoustophoretic Liquefaction for 3D Printing Ultrahigh‐Viscosity Nanoparticle Suspensions
Authors: Liu Zheng , Pan Wenyang , Wang Kaiyang , Matia Yoav , Xu Artemis , Barreiros Jose A. , Darkes‐Burkey Cameron , Giannelis Emmanuel P. , Mengüç Yiğit , Shepherd Robert F. , Wallin Thomas J. 
Published: October 2021

AbstractAn acoustic liquefaction approach to enhance the flow of yield stress fluids during Digital Light Processing (DLP)‐based 3D printing is reported. This enhanced flow enables processing of ultrahigh‐viscosity resins (μapp > 3700 Pa s at shear rates = 0.01 s–1) based on silica particles in a silicone photopolymer. Numerical simulations of the acousto–mechanical coupling in the DLP resin feed system at different agitation frequencies predict local resin flow velocities exceeding 100 mm s–1 at acoustic transduction frequencies of 110 s–1. Under these conditions, highly loaded particle suspensions (weight fractions, ϕ = 0.23) can be printed successfully in complex geometries. Such mechanically reinforced composites possess a tensile toughness 2000% greater than the neat photopolymer. Beyond an increase in processible viscosities, acoustophoretic liquefaction DLP (AL‐DLP) creates a transient reduction in apparent viscosity that promotes resin recirculation and decreases viscous adhesion. As a result, acoustophoretic liquefaction Digital Light Processing (AL‐DLP) improves the printed feature resolution by more than 25%, increases printable object sizes by over 50 times, and can build parts >3 × faster when compared to conventional methodologies.
Heterointerface Engineering in Electromagnetic Absorbers: New Insights and Opportunities
Authors: Liang Leilei , Gu Weihua , Wu Yue , Zhang Baoshan , Wang Gehuan , Yang Yi , Ji Guangbin 
Published: October 2021

AbstractElectromagnetic (EM) absorbers play an increasingly essential role in the electronic information age, even toward the coming “intelligent era”. The remarkable merits of heterointerface engineering and its peculiar EM characteristics inject a fresh and infinite vitality for designing high‐efficiency and stimuli‐responsive EM absorbers. However, there still exist huge challenges in understanding and reinforcing these interface effects from the micro and macro perspectives. Herein, EM response mechanisms of interfacial effects are dissected in depth, and with a focus on advanced characterization as well as theoretical techniques. Then, the representative optimization strategies are systematically discussed with emphasis on component selection and structural design. More importantly, the most cutting‐edge smart EM functional devices based on heterointerface engineering are reported. Finally, current challenges and concrete suggestions are proposed, and future perspectives on this promising field are also predicted.
Effects of surface species and homogeneous reactions on rates and selectivity in ethane oxidation on oxide catalysts
Authors: Liu Yilang , McGill Charles J. , Green William H. , Deshlahra Prashant 
Published: October 2021

AbstractSelective alkane oxidations on metal oxide catalysts involve complex mechanisms with multiple reactions in series and parallel, different types of reduced and oxidized surface species, and potential contributions from gas‐phase reactions. Here, kinetics and thermodynamics of elementary steps involved in C2H6‐O2 reactions on SiO2‐supported small vanadium oxide domains are determined using density functional theory. These surface reactions together with gas‐phase mechanisms are incorporated in kinetic simulations to determine how surface and gaseous reactions interact and contribute to rates and selectivity. The results show that gas‐phase reactions within pore volumes in contact with the catalyst contribute significantly to C2H6 activation rates, even at conditions where gas‐phase reactions in empty volumes without catalyst are negligible. The majority of C2H6 activations occur on the surface, via H abstraction by vanadium oxo species present at terminal lattice oxygens. The gas‐phase activations via H‐abstraction by OH radicals also exhibit significant contributions. The reduced centers formed by reactions at vanadium oxo species are re‐oxidized rapidly and, therefore, are present in very small concentrations at reaction conditions. The re‐oxidation steps lead to the formation of HO2 radicals and surface peroxo species that are also rapidly consumed and are present in small concentrations. The peroxo species preferentially convert C2H4 to its epoxide product and influence selectivity even at low concentrations. The gas‐phase reactions decrease the concentrations of peroxo species and improve selectivity slightly. The effects of reaction conditions and catalyst site density provide further insights into how factors beyond conversions at lattice oxygens influence rates and selectivity in alkane oxidation reactions of significant industrial importance.
Hyperbranched polyglycerols derivatives as cetyltrimethylammonium bromide nanocarriers on enhanced oil recovery processes
Authors: Ferreira Conny Cerai , da Silva Thais Barros Gomes , Francisco Agatha Densy dos Santos , Bandeira Lucas , Cunha Renato D. , Coutinho‐Neto Mauricio Domingues , Homem‐de‐Mello Paula , Moraes de Almeida James , Orestes Ednilsom , Nascimento Regina Sandra Veiga 
Published: October 2021

AbstractIn this work, the efficiency of partially hydrophobized hyperbranched polyglycerols (HPG11 and HPG12) as cetyltrimethylammonium bromide (CTAB) carriers was evaluated to prevent surfactant losses by adsorption on reservoir rocks surface during enhanced oil recovery (EOR) processes. Interactions between surfactant and polymers were studied by conductivity, zeta potential, and particle size measurements showing that complexes were formed between the components. The ability of PG, HPG11, HPG12 and those complexes to reduce the interfacial tension (IFT) was verified and one of the complexes was able to reduce the IFT to values under 1.0 mN/m, suggesting the occurrence of a synergy between the components. Molecular dynamics simulations indicated the preferential sites of interaction between surfactants and HPGs. HPG11:CTAB and HPG12:CTAB complexes' ability to permeate an unconsolidated porous medium and deliver the surfactant at the water–oil interface, increasing oil production, was evaluated through transport and oil displacement tests, and the results showed that the HPG12:CTAB complex led to almost 90% of oil recovery.
Assisting researchers in bibliographic tasks: A new usable, real‐time tool for analyzing bibliographies
Authors: Dattolo Antonina , Corbatto Marco 
Published: October 2021

AbstractThe amount of scientific papers is growing together with the development of science itself; but, although there is an unprecedented availability of large citation indexes, some daily activities of researchers remain time‐consuming and poorly supported. In this paper, we present Visual Bibliographies (VisualBib), a real‐time visual platform, designed using a zz‐structure‐based model for linking metadata and a narrative, visual approach for showing bibliographies. VisualBib represents a usable, advanced, and visual tool, which simplifies the management of bibliographies, supports a core set of bibliographic tasks, and helps researchers during complex analyses on scientific bibliographies. We present the variety of metadata formats and visualization methods, proposing two use case scenarios. The maturity of the system implementation allowed us two studies, for evaluating both the effectiveness of VisualBib in providing answers to specific data analysis tasks and to support experienced users during real‐life uses. The results of the evaluation are positive and describe an effective and usable platform.
Association between descriptive and injunctive norms and students' intentions to seek support from mental health services
Authors: Eritsyan Ksenia , Antonova Natalia , Kazantseva Tatiana , Usacheva Nina 
Published: October 2021

AbstractObjectivesThis study explores the factors involved in the intention to seek support from mental health services among students, emphasising the role of subjective norms in this process.MethodsFactors involved in students’ intentions to seek support from mental health services were explored using regression analysis, based on survey data from 1,494 Russian students (from high schools, vocational schools and universities). Independent variables included perceived injunctive and descriptive norms towards mental health help‐seeking, previous experience of utilising mental health services and mental health symptoms.FindingsLess than a quarter of students had the intention to seek psychological help in case of distress. Just half of the students felt that others would support them in seeking psychological help (injunctive social norms), although only 10% believed their peers would seek help when needed (descriptive norms). Only injunctive, but not descriptive, social norms were associated with the intention to seek help. Experience of visiting a psychologist (only in the case of self‐referral) was another important predictor of intention to seek help. Male students and those who considered their mental health to be bad or perfect showed less intention to seek help.ConclusionProvision of mental health services for students should be accompanied by interventions aimed at establishing positive attitudes towards mental health‐seeking among the general population, particularly those whose opinion is important for students. A gender‐specific approach should be introduced in delivering and promoting mental health care since male students are more hesitant to accept care and might face strong negative feedback from their social environment when doing so.
Reports of Animal Abuse in Child Protection Referrals: A Study of Cases from One South Australian Service
Authors: Riggs Damien W. , Baum Naomi G. , Taylor Nik , Beall Jacqui 
Published: October 2021

Key Practitioner Messages

There is a well‐established link between animal‐ and human‐directed violence.
Reports of animal abuse in child protection referrals may indicate more severe cases of child abuse.
Cross‐reporting of abuse is important, both in the context of child protection and animal welfare.
‘There is a well‐established link between animal‐ and human‐directed violence’
Identifying nesting grounds for juvenile migratory birds with dual isotope: an initial test using North American raptors
Authors: Crowley Brooke E. , Bataille Clément P. , Haak Bruce A. , Sommer Kaitlin M. 
Published: October 2021

AbstractUnderstanding seasonal mobility, population connectivity, and site fidelity is critical for managing and preserving migratory species. We investigated the potential of coupling strontium (87Sr/86Sr) and hydrogen (δ2H) isotopes in feathers for quantitatively constraining natal origin for juvenile migratory predatory birds (raptors) using a probabilistic framework. We first calibrated single‐isotope models that predict spatial isotope variability in raptor feathers (called isoscapes) by analyzing and compiling isotope data for juvenile birds with known origins in North America and comparing their values to existing isotopic baselines in precipitation (for δ2H) and bioavailable strontium (for 87Sr/86Sr). We then compared the potential of hydrogen and strontium isotopes for refining geographic assignments either independently or combined. While yielding very different probability maps, hydrogen and strontium isotopes performed equally well at constraining regions of natal origin. However, thanks to the complementarity of these isotopes, dual δ2H and 87Sr/86Sr assignments increased predictive precision by an order of magnitude compared to either isotope alone. Lastly, we used the models to predict natal origin for juveniles with unknown origins that were sampled in southwestern Idaho, USA, during their autumn migration. The precision of geographic assignments for birds with unknown origins varied. Nevertheless, dual‐isotope assignments clearly distinguished individuals born outside of southwestern Idaho, and overall, predicted geographic assignments matched breeding ranges for the study species. Quantitative dual‐isotope geographic assignments enhance our ability to predict natal range of migratory raptors and complement other methods for monitoring movement and population connectivity. Combining isotopic data from feathers with other intrinsic geochemical and genetic data, as well as extrinsic markers, such as transmitters or bands, and niche‐modeling approaches will further refine key nesting areas for migratory birds.
Comparative effects of on‐pump versus off‐pump coronary artery bypass grafting surgery on serum cytokine and chemokine levels
Authors: Mirhafez Seyed Reza , Khadem Seyedeh Hamideh , Sahebkar Amirhossein , Movahedi Ali , Rahsepar Amir Ali , Mirzaie Asadollah , Jamialahmadi Tannaz , Ferns Gordon A. , Ghayour‐Mobarhan Majid 
Published: October 2021

AbstractCoronary artery bypass grafting (CABG) surgery with two methods (on‐pump or off‐pump) can be used to rescue individuals with severe coronary artery disease (CAD). Each method might cause an inflammatory response, which can lead to some complications. The aim of this study was to compare the changes in serum concentrations of IFN‐γ, tumor necrosis factor (TNF)‐α, interleukin (IL)‐1α, IL‐1β, IL‐2, IL‐4, IL‐6, IL‐8, IL‐10, VEGF, MCP‐1, and epidermal growth factor between the two CABG surgery methods. Forty‐eight patients (22 = on‐pump, 26 = off‐pump) who underwent on‐pump or off‐pump CABG surgery were enrolled in this study. Serum cytokines levels were measured in two blood samples, the first sample was taken from each patient in the morning of the day of surgery after a 12‐hr fasting and the second sample on the first postoperative day at 24‐hr after surgery. In baseline, comparisons between the two groups of on‐pump/off‐pump surgery did not show any significant difference in demographic data, anthropometric parameters, lipid profile indices, and high‐sensitivity C‐reactive protein levels (p > .05). There was a significant difference between the serum levels of IL‐4, IL‐6, IL‐10, vascular endothelial growth factor (VEGF), IFN‐γ, and MCP‐1 in patients with on‐pump surgery and a significant increase in serum IL‐6 (p < .001), IL8 (p < .05), VEGF (p < .001), and IFN‐γ (p < .01) levels in patients with off‐pump surgery in post‐operation stage compared to pre‐operation. Cardiopulmonary pump in patients under CABG surgery can activate systemic inflammation and the changes of serum cytokines levels in off‐pump CABG were lower compared with on‐pump CABG.