bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tackling multimorbidity: staff perceptions of the transition from single-condition rehabilitation to a specialist-generalist model
Authors: Cowie Aynsley , Good Kathy , McKay Janet , Holt Jane 
Published: August 2021

Background/aims The Healthy and Active Rehabilitation Programme is a specialist-generalist approach to targeting multimorbidity, which was developed through reconfiguring single-condition rehabilitation pathways. This project examined staff perceptions of the transition from specialist rehabilitation, to delivering this new model. Methods A total of 18 staff from the Healthy and Active Rehabilitation Programme (eight nurses, seven exercise instructors, two physiotherapists, one occupational therapist) participated in three focus groups, generating three key themes: apprehension, confidence growth, and integrated working. Results Despite initial apprehension around the Healthy and Active Rehabilitation Programme's impact on the existing service, the service users, and their clinical roles, staff developed confidence in the service and in their broader roles. Integrated working within the Healthy and Active Rehabilitation Programme has enhanced their awareness of the wider rehabilitation team, and provides valuable peer support. Conclusions This project provides valuable information for single-condition rehabilitation services that are considering delivery of specialist-generalist care to help target multimorbidity.
Utilizing thermally induced selective mode shaping for a high extinction ratio in-line fiber modulator/polarizer
Authors: Heidari Mohsen 
Published: August 2021

Light–matter interactions of guided modes strongly depend on mode shape. This Letter presents an ultrahigh extinction ratio (ER) polarizer/modulator at

λ
=
1.55

µ

m

, enabled by selective mode reshaping for different orthogonal modes. This bi-function device benefits from a designed side-polished fiber (SPF) with a three-layer stack of graphene/

V
O

2

/PMMA overlay. Thermally induced insulator-metal transition (IMT) in

V
O

2

via a graphene microheater leads to the polarization-selective mode shaping (PSMS), which is used to manipulate orthogonal modes separately. As a result, a TE modulator (TM-pass polarizer) with an ultrahigh

E
R

=

168.4

d
B

/

m
m

(175.1 dB/mm) and low insertion loss (IL) of

I
L

=

3.38

d
B

/

m
m

(0.34 dB/mm) is achieved.
A multi-objective genetic algorithm to find active modules in multiplex biological networks
Authors: Novoa-del-Toro Elva María , Mezura-Montes Efrén , Vignes Matthieu , Térézol Morgane , Magdinier Frédérique , Tichit Laurent , Baudot Anaïs 
Published: August 2021

The identification of subnetworks of interest—or active modules—by integrating biological networks with molecular profiles is a key resource to inform on the processes perturbed in different cellular conditions. We here propose MOGAMUN, a Multi-Objective Genetic Algorithm to identify active modules in MUltiplex biological Networks. MOGAMUN optimizes both the density of interactions and the scores of the nodes (e.g., their differential expression). We compare MOGAMUN with state-of-the-art methods, representative of different algorithms dedicated to the identification of active modules in single networks. MOGAMUN identifies dense and high-scoring modules that are also easier to interpret. In addition, to our knowledge, MOGAMUN is the first method able to use multiplex networks. Multiplex networks are composed of different layers of physical and functional relationships between genes and proteins. Each layer is associated to its own meaning, topology, and biases; the multiplex framework allows exploiting this diversity of biological networks. We applied MOGAMUN to identify cellular processes perturbed in Facio-Scapulo-Humeral muscular Dystrophy, by integrating RNA-seq expression data with a multiplex biological network. We identified different active modules of interest, thereby providing new angles for investigating the pathomechanisms of this disease.Availability:MOGAMUN is available athttps://github.com/elvanov/MOGAMUNand as a Bioconductor package athttps://bioconductor.org/packages/release/bioc/html/MOGAMUN.html.Contact:anais.baudot@univ-amu.fr
Passive surveillance of human African trypanosomiasis in Côte d’Ivoire: Understanding prevalence, clinical symptoms and signs, and diagnostic test characteristics
Authors: Koné Minayégninrin , Kaba Dramane , Kaboré Jacques , Thomas Lian Francesca , Falzon Laura Cristina , Koffi Mathurin , Kouamé Cyrille Mambo , Ahouty Bernardin , Compaoré Charlie Franck Alfred , N’Gouan Emmanuel Kouassi , Solano Philippe , Fèvre Eric , Büscher Philippe , Lejon Veerle , Jamonneau Vincent 
Published: August 2021

Background
Little is known about the diagnostic performance of rapid diagnostic tests (RDTs) for passive screening of human African trypanosomiasis (HAT) in Côte d’Ivoire. We determined HAT prevalence among clinical suspects, identified clinical symptoms and signs associated with HAT RDT positivity, and assessed the diagnostic tests’ specificity, positive predictive value and agreement.

Methods
Clinical suspects were screened with SD Bioline HAT, HAT Sero-K-Set and rHAT Sero-Strip. Seropositives were parasitologically examined, and their dried blood spots tested in trypanolysis, ELISA/Tbg, m18S-qPCR and LAMP. The HAT prevalence in the study population was calculated based on RDT positivity followed by parasitological confirmation. The association between clinical symptoms and signs and RDT positivity was determined using multivariable logistic regression. The tests’ Positive Predictive Value (PPV), specificity and agreement were determined.

Results
Over 29 months, 3433 clinical suspects were tested. The RDT positivity rate was 2.83%, HAT prevalence 0.06%. Individuals with sleep disturbances (p<0.001), motor disorders (p = 0.002), convulsions (p = 0.02), severe weight loss (p = 0.02) or psychiatric problems (p = 0.04) had an increased odds (odds ratios 1.7–4.6) of being HAT RDT seropositive. Specificities ranged between 97.8%-99.6% for individual RDTs, and 93.3–98.9% for subsequent tests on dried blood spots. The PPV of the individual RDTs was below 14.3% (CI 2–43), increased to 33.3% (CI 4–78) for serial RDT combinations, and reached 67% for LAMP and ELISA/Tbg on RDT positives. Agreement between diagnostic tests was poor to moderate (Kappa ≤ 0.60), except for LAMP and ELISA/Tbg (Kappa = 0.66).

Conclusion
Identification of five key clinical symptoms and signs may simplify referral for HAT RDT screening. The results confirm the appropriateness of the diagnostic algorithm presently applied, with screening by SD Bioline HAT or HAT Sero-K-Set, supplemented with trypanolysis. ELISA/Tbg could replace trypanolysis and is simpler to perform.

Trial registration
ClinicalTrials.gov NCT03356665.
Tobacco control policies and smoking cessation treatment utilization: A moderated mediation analysis
Authors: Thrul Johannes , Riehm Kira E. , Cohen Joanna E. , Alexander G. Caleb , Vernick Jon S. , Mojtabai Ramin 
Published: August 2021

Background
Tobacco policies, including clean indoor air laws and cigarette taxes, increase smoking cessation in part by stimulating the use of cessation treatments. We explored whether the associations between tobacco policies and treatment use varies across sociodemographic groups.

Methods
We used data from 62,165 U.S. adult participants in the 2003 and 2010/11 Tobacco Use Supplement to the Current Population Survey (TUS-CPS) who reported smoking cigarettes during the past-year. We built on prior structural equation models used to quantify the degree to which smoking cessation treatment use (prescription medications, nicotine replacement therapy, counseling/support groups, quitlines, and internet resources) mediated the association between clean indoor air laws, cigarette excise taxes, and recent smoking cessation. In the current study, we added selected moderators to each model to investigate whether associations between tobacco polices and smoking cessation treatment use varied by sex, race/ethnicity, education, income, and health insurance status.

Results
Associations between clean indoor air laws and the use of prescription medication and nicotine replacement therapies varied significantly between racial/ethnic, age, and education groups in 2003. However, none of these moderation effects remained significant in 2010/11. Higher cigarette excise taxes in 2010/2011 were associated with higher odds of using counseling among older adults and higher odds of using prescription medications among younger adults. No other moderator reached statistical significance. Smoking cessation treatments did not mediate the effect of taxes on smoking cessation in 2003 and were not included in these analyses.

Conclusions
Sociodemographic differences in associations between clean indoor air laws and smoking cessation treatment use have decreased from 2003 to 2010/11. In most cases, policies appear to stimulate smoking cessation treatment use similarly across varied sociodemographic groups.
Associations of SARS-CoV-2 serum IgG with occupation and demographics of military personnel
Authors: Zell Joseph , Wisnewski Adam V. , Liu Jian , Klein Jon , Lucas Carolina , Slade Martin , Iwasaki Akiko , Redlich Carrie A. 
Published: August 2021

Background
Countries across the globe have mobilized their armed forces in response to COVID-19, placing them at increased risk for viral exposure. Humoral responses to SARS-CoV-2 among military personnel serve as biomarkers of infection and provide a basis for disease surveillance and recognition of work-related risk factors.

Methods
Enzyme-linked immunosorbent assays (ELISA) were used to measure SARS-CoV-2 spike antigen-specific IgG in serum obtained from N = 988 US National Guard soldiers between April-June 2020. Occupational information, e.g. military operating specialty (MOS) codes, and demographic data were obtained via questionnaire. Plaque assays with live SARS-CoV-2 were used to assess serum neutralizing capacity for limited subjects (N = 12).

Results
The SARS-CoV-2 IgG seropositivity rate among the study population was 10.3% and significantly associated with occupation and demographics. Odds ratios were highest for those working in MOS 2T-Transportation (3.6; 95% CI 0.7–18) and 92F-Fuel specialist/ground and aircraft (6.8; 95% CI 1.5–30), as well as black race (2.2; 95% CI 1.2–4.1), household size ≥6 (2.5; 95% CI 1.3–4.6) and known COVID-19 exposure (2.0; 95% CI 1.2–3.3). Seropositivity tracked along major interstate highways and clustered near the international airport and the New York City border. SARS-CoV-2 spike IgG+ serum exhibited low to moderate SARS-CoV-2 neutralizing capacity with IC50s ranging from 1:15 to 1:280. In limited follow-up testing SARS-CoV-2 serum IgG levels remained elevated up to 7 months.

Conclusions
The data highlight increased SARS-CoV-2 seroprevalence among National Guard vs. the local civilian population in association with transportation-related occupations and specific demographics.
Photography from the Turin Shroud to the Turing Machine, Yanai Toister (2020)
Authors: Lechte John 
Published: August 2021

Review of: Photography from the Turin Shroud to the Turing Machine, Yanai Toister (2020)
Bristol and Chicago, IL: Intellect, p/bk, 215 pp.,
ISBN 978-1-78938-156-6, p/bk, £37
Psychiatric Disease Susceptibility and Pain in Chronic Pancreatitis: Association or Causation?
Authors: Faghih Mahya , Drewes Asbjørn M. , Singh Vikesh K. 
Published: August 2021

Abstract
Pain perception in chronic pancreatitis (CP) is governed by the transmission of nociceptive inputs into the pain processing centers of the brain. These regions of the brain overlap with those that regulate and process emotions and cognition. Disorders in these regions also result in psychiatric conditions such as depression, anxiety, and posttraumatic stress disorder. The present study by Dunbar et al. evaluated 24 single nucleotide polymorphisms associated with anxiety and/or posttraumatic stress disorder and found correlations with constant and severe pain phenotypes in CP patients from a large cross-sectional cohort study. Although causation cannot be proven, the findings suggest that there may be a role for neuromodulator drugs for the treatment of pain in CP based on individual genetic susceptibility.
Ensor networks – distributed information measuring and information control systems
Authors: Likhttsinder Boris Ya. 
Published: August 2021

The problems of control and management of geographically distributed objects are considered. The sensor networks operating on the ZigBee technology are considered. The characteristics of the 802.15.4 ZigBee standard are given. The advantages of this technology are shown when building networks that are not very critical to traffic delays. The elements of such a network are considered. The primary converters used in such networks and their energy characteristics are considered. The issues of reducing and compensating delays in control circuits are considered.
It is shown that modern wireless sensor networks can be considered as distributed information measuring and information control systems.
Unplanned Coordination: Ensemble Improvisation as Collective Action
Authors: Hasan Ali , Kayle Jennifer 
Published: August 2021

AbstractThe characteristic features of ensemble dance improvisation (EDI) make it an interesting case for theories of intentional collective action. These features include the high degree of freedom enjoyed by each individual, and the lack of fixed hierarchical roles, rigid decision procedures, or detailed plans. We present a “reductive” approach to collective action, apply it to EDI, and show how the theory enriches our perspective on this practice. We show, with the help of our theory of collective action, that EDI (as typically practiced) constitutes a significant collective achievement, one that manifests an impressive, spontaneous, jointly cooperative and individually highly autonomous activity that meets demanding aesthetic standards. Its being good in this way is not a mere extrinsic feature of the artwork, but part of its aesthetic value. We end by discussing how this value is easily missed by classic aesthetics, but is revealed by more contemporary frameworks like social aesthetics.
Justice and Authority in Investment Protection
Authors: Suttle Oisin 
Published: August 2021

AbstractWhat role should concerns about distributive justice play in international investment law? This paper argues that answers to fundamental and contestable questions of social and global distributive justice are a necessary, if implicit, premise of international investment law. In particular, they shape our views on the purpose of investment law, and in turn determine the scope of authority that investment law can claim, and that states should accord it. The implausibility of achieving international consensus on these questions constitutes a substantial objection to the harmonization of investment law or the consistent operation of a multilateral investment court.
Digital Literacy of EFL Students: An Empirical Study in Vietnamese Universities
Authors: Nguyen Lan Anh Thuy , Habók Anita 
Published: August 2021

AbstractThe current research investigates the digital literacy levels of 1661 English as a foreign language (EFL) learner at Vietnamese universities. We used an adapted questionnaire to assess students’ digital knowledge and their perceived skills, their attitudes toward the use of digital technologies, and the frequency of use of technology applications in English learning. The findings reveal that most Vietnamese students can access digital technologies at home and in their institutions. Furthermore, students achieve an adequate level of knowledge regarding digital literacy, and their technological skills range from low to average. Students’ attitudes toward technologies are positive, but they do not use technologies extensively when learning English. Comparisons show that males have better digital knowledge and skills than their female peers. Although female students are more aware of the digital integration benefits of learning than their male peers, males tend to use technologies more extensively than females. There are also discrepancies among different year groups. Seniors have the best digital knowledge, while freshmen possess the highest technical skill levels. Junior and senior students’ attitudes toward technology applications in English learning are more positive than those of freshmen and sophomores.
Independence and generalizability in linguistics
Authors: Winter Bodo , Grice Martine 
Published: August 2021

AbstractQuantitative studies in linguistics almost always involve data points that are related to each other, such as multiple data points from the same participant, multiple texts from the same book, author, genre, or register, or multiple languages from the same language family. Statistical procedures that fail to account for the relatedness of observations by assuming independence among units can lead to grossly misleading results if these sources of variation are ignored. As mixed effects models are increasingly used to analyze these non-independent data structures, it might appear that the problem of violating the independence assumption is solved. In this paper, we argue that it is necessary to re-open and widen the discussion about sources of variation that are being ignored, not only in statistical analyses, but also in the way studies are designed. Non-independence is not something that is “solved” by new statistical methods such as mixed models, but it is something that we continuously need to discuss as we apply new methods to an increasingly diverse range of linguistic datasets and corpora. In addition, our paper delivers something that is currently missing from statistical textbooks for linguists, which is an overview of non-independent data structures across different subfields of linguistics (corpus linguistics, typology, phonetics etc.), and how mixed models are used to deal with these structures.
Crystal structure of 2,2′-(propane-1,3-dilylbis(azaneylylidene))bis(methanylylidene)bis(4-methylphenol), C19H22N2O2
Authors: Orang’o Daniel M. , Onani Martin O. , Tarus Paul K. , Lutta Samuel T. , Lalancette Roger A. 
Published: August 2021

Abstract
C19H22N2O2, monoclinic, P21/c (no. 14), a = 19.3063(4) Å, b = 5.83200(10) Å, c = 14.7996(3) Å, β = 92.715(1)°, V = 1664.48(6) Å3, Z = 4, R

gt
(F) = 0.0423, wR

ref
(F
2) = 0.1102, T = 100(2) K.
Cultivation as Immanent Critique: Horticultural Metaphors in Gregory of Nyssa’s Reception of Origen and Basil
Authors: Ross Taylor 
Published: August 2021

Abstract
The present article asks after Gregory of Nyssa’s debts to Basil the Great, and this by re-examining two texts the former wrote shortly after the latter’s death: De hominis opificio and Apologia in Hexaemeron. It does so on the premise, mostly promissory for now, that Gregory’s efforts to sort through Basil’s legacy in his late brother’s wake was part and parcel of the Nyssen’s career-long project to reprise Origen of Alexandria under a “pro-Nicene” banner. Defending his elder sibling’s apparently incomplete Homiliae in Hexameron while also disputing their basic premise, that is, gave Gregory an opportunity to negotiate the dialectic of dependence and distinction that ultimately determined his reception of earlier authorities, including the great Alexandrian they both revered. With that much longer story in sight, this article focuses on Gregory’s deployment of horticultural metaphors, especially in the Apologia in Hexaemeron, to describe his stance toward both Basil and Origen. Closer scrutiny of these images alongside his more technical means of differentiating between himself and Basil suggests that Gregory considered his own work to be both a natural development of his predecessors and, precisely thereby, the immanent perfection of their thought.
Investigation of measurement data of low-coherence interferometry at tilted surfaces in the 3D spatial frequency domain
Authors: Künne Marco , Hagemeier Sebastian , Käkel Eireen , Hillmer Hartmut , Lehmann Peter 
Published: August 2021

Abstract
The 3D transfer characteristics of interference microscopes and their effect on the interference signals occurring at surface slopes are studied. The interference image stacks acquired during a depth scan are 3D Fourier transformed. This allows a comprehensive frequency domain analysis of the interferograms. The double foil model introduced in a previous publication enables the interpretation of the signal spectra and the underlying transfer behavior of the interferometer using the concept of the Ewald sphere, which is limited by the numerical aperture (NA) of the imaging system. Analysis in the 3D spatial frequency domain directly discloses that the lateral dimensions of the transfer function depend on the axial spatial frequency. In this contribution we investigate measuring objects produced by Nanoimprint-Lithography. The corresponding signal spectra bear information that can be utilized to optimize the subsequent signal processing algorithms. These include envelope and phase evaluation procedures of the interference signals. A narrow bandpass filter is used to actively select certain frequency components in order to improve the robustness of the estimation of the envelope position. Although the shape and width of the envelope are affected, this procedure increases the reliability of the evaluation process and improves the accuracy of the measured topography especially at steeper surface slopes.
Non-invasive aberration correction and adaptive ultrasound imaging with a time reversal virtual array
Authors: Grüter Lars , Nauber Richard , Czarske Jürgen 
Published: August 2021

Abstract
Strong acoustical aberrations such as induced by multi-mode waveguides or the human skull can significantly reduce the quality of or prevent effective ultrasoundbased imaging. We propose a novel non-invasive calibration method that utilizes two independent acoustical accesses and a time reversal virtual array (TRVA) for adaptive wavefront correction. Numerical characterization and a model experiment utilizing this method show an improvement of the lateral resolution and the peak to background ratio by up to 35% and 10% respectively.
Substitutionsmessung von Massenormalen unter Verwendung neuartiger Transferkörper
Authors: Lehrmann Katharina , Härtig Frank 
Published: August 2021

Zusammenfassung
Im Bereich der Massekalibrierung können systematische Abweichungen von Massenormalen mit unterschiedlichen Materialien und Geometrien durch sogenannte Transferkörper bestimmt und korrigiert werden. Vorgestellt werden neuartige Transferkörper aus monokristallinem natürlichem Silizium. Diese haben seit der Revision des Internationalen Einheitensystem (SI) eine besondere Bedeutung. Erläutert werden Anforderungen, die an Sorptions-, Duplex- und Auftriebskörper gestellt werden, um die Einflüsse von Oberflächenbelegungen und Luftauftrieb zu charakterisieren. Beschrieben werden die mathematischen Modelle und die iterativen Lösungswege, mit denen transzendente Gleichungen zur Bestimmung der Geometrie gelöst wurden. Eine patentierte Kupplung ermöglicht eine statisch bestimmte Lagerung der zerlegbaren Transferkörper und gewährleistet zudem die besonderen Anforderungen einer einfachen Handhabung und Reinigung. Die Ergebnisse mittels Monte-Carlo-Simulationen zeigen, welche Messunsicherheiten für die Parameter Volumen, Fläche und Masse erreicht werden.