bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaporation of R32/R1234yf Mixture on the Wall: A Molecular Dynamics Study
Authors: Xia Di , Shen Hongtao , Xiong Jianjun , Han Guodong 
Published: August 2021

Abstract
The mixed refrigerants have a great potential in the energy industry, while the micro-mechanism of evaporation of mixed refrigerants is still unclear. Therefore, molecular dynamics simulations were employed to investigate the evaporation of the R32, R1234yf and their mixture on the Pt surface at 230 K, 250 K and 350 K, respectively. The results indicate that the presence of R1234yf will suppress the evaporation of R32. The adsorption interaction between R32 and substrate is lower than that of R1234yf. The film boiling is found at high temperature evaporation. Meanwhile, the heat flux of the system decreases due to the heat transfer deterioration.
Research review on the Key Technology of Preventive Maintenance: The Durability of 4.75mm NMAS Stone Mastic Asphalt (SMA-5) Ultra-thin Overlay
Authors: Liu Jingxian , Wei Shucai , Ling Yuwei , Tai Jiahao , Shao Chenfeng , Zhu Siyue 
Published: August 2021

Abstract
SMA-5 Ultra-thin Overlay is a kind of preventive maintenance material which has the advantages of fast construction, good surface texture depth, cost-effective and environmentally friendly. It is also suitable for the maintenance of bridge and tunnel which have restriction on elevation. However, the insufficient durability is the key factor which restricts the development of SMA-5. This article summarizes the key technology to enhance the durability of SMA-5 in terms of its material composition, grading and mixture design methods, which provide a reference for improving the durability of SMA-5 and promoting the application of SMA-5.
Dynamic response of hollow sandwich cement rod of 110 Kv transmission line
Authors: Xingeng Li , Bichuan Fu , Yuheng Ouyang 
Published: August 2021

Abstract
Taking a 110 kV transmission line as the research object, a refined finite element model of three pole two line transmission tower line system is established.Considering collision and contact between a dropped wire and ground, nonlinear dynamic analyses of the system with different break points and different numbers of broken wires were performed. The results showed that the break point location has little effects on the impact action of broken wire; the tension decay coefficient of the broken wire decreases with increase in the height of the hanging point position, while that of the unbroken wire decreases first and then increases with increase in the height of the hanging point position. The initial pretension, wind direction angle and span of the cable are selected for parameter analysis. The influence of these parameters on the nonlinear dynamic stability critical load of the hollow mezzanine concrete pole line system is investigated.
Study on polyester fabric grafted with acrylic acid initiated by ultraviolet light
Authors: Xin-Cheng Xie , Xiao-Jing Yi , Wen Huang , Zuo-Shen Li , Xin-Long Ling 
Published: August 2021

Abstract
Polyester fabric has compact molecular chain structure, high crystallinity, no hydrophilic groups except hydroxyl groups at both ends, and poor hygroscopicity. The surface of polyester fabric was modified with acrylic acid by ultraviolet light in order to improve its hydrophilicity. The best technological conditions are as follows: the concentration of acrylic acid is 10%, the irradiation time is 1 hour, and the concentration of photoinitiator is 5%. Under the optimum conditions, acrylic acid is successfully grafted onto the surface of polyester fabric. There are grafting polymer between the fiber gaps or on the surface of fiber, accompanied by cross-linking or bonding. The hydrophilicity and dyeing rate of modified polyester fabric are improved obviously. The breaking strength and elongation at break of treated polyester fabric increases and decreases, respectively.
Functionalized α-GDY with different displacement distance for CO2/CH4 diffusion and separation
Authors: Sainan Zhou , Huili Xin , Wanru Zhai , Shengyu Xu , Sen Liu , Hao Dong , Xiaoqing Lu 
Published: August 2021

Abstract
Functionalized α-GDY with – H, – F, and – N for different displacement distance were designed as promising membranes for separation CO2 from CH4 by using molecular dynamics simulations. The α-GDY were regulated to form suitable pore sizes by functionalization and displacement for separation CO2 from CH4. F-GDY membranes and displacement distance with 1/3 have ultralow CO2 selectivity over N2 of ~0, which indicate that no CO2 pass through F-GDY membranes and CO2 and CH4 were separated efficiently. Among these membranes, N-GDY with 1/3 displacement distance has highest permeance of 5.97 × 10-5 mol m-2 s-1 Pa-1 at 300 K. Relative concentrations distribution confirmed that almost CO2 molecules adsorbed the pore wall of membrane, CH4 distributed in the gas box and vacuum. The interaction energy between gas molecules and membrane was analyzed to elucidate the significant impact of functionalization on the selectivity of CO2 over CH4 and CH4 permeances passing through porous BN membranes.
Research progress in damage assessment methods for tight sandstone gas reservoirs
Authors: Zhou Guangxu , Ye Yan , Zhou Fujian 
Published: August 2021

Abstract
In the process of oil and gas development, the perfect reservoir damage evaluation method is an important condition to realize the economical and efficient development of the reservoir. At present, great progress has been made in the exploration of tight oil and gas. However, due to the characteristics of low porosity, low permeability and low water saturation of tight sandstone gas reservoirs, conventional reservoir damage evaluation methods are not applicable to it, and no systematic evaluation method has been formed yet. The damage evaluation methods of tight sandstone gas reservoirs mainly include the steady-state method and the unsteady-state method. The steady-state method is mainly the high temperature and high back pressure method, while the unsteady-state methods are the pressure attenuation method and the pressure transmission method which are widely applicable. Visualization technology, microfluidic technology, flow rate evaluation method and recovery evaluation method are the new methods to evaluate reservoir damage, which are in the further research. This paper summarizes the research progress of reservoir damage evaluation methods for tight sandstone gas reservoirs, analyzes the main evaluation methods, experimental equipment and improvement measures, and points out the problems that need to be paid attention to and solved, in order to provide reference for efficient and accurate evaluation of reservoir damage in tight sandstone gas reservoirs.
Prediction of shale oil production based on Prophet algorithm
Authors: Wan Xiaolong , Zou Yongling , Wang Juan , Wang Weina 
Published: August 2021

Abstract
The large-scale volume fracturing development of shale oil horizontal wells, and the production is affected by seasonal cycle and emergencies, resulting in the complexity of production prediction. Aiming at the problem of poor actual effect or heavy workload of shale oil production prediction by classical reservoir engineering, reservoir numerical simulation and other methods, a new shale oil production prediction method based on Prophet algorithm is proposed It is easier to find the inherent law from a small amount of data. In this paper, we use the production data of production wells in Huanjiang A reservoir in 2015 to predict the production, and compare the prediction results with long-term and short-term memory neural network (LSTM) and ARPS production decline model. The results show that the prediction accuracy of Prophet algorithm is higher, and it is more accurate for the production of complex shale oil.
Disposable enzyme-free glucose biosensor based on H-rGO-Pt@Pd NPs/Au NPs
Authors: Shi Xiaohang , Wang Tong , Wang Bo , Li Guiyin , Liang Jintao 
Published: August 2021

Abstract
In this study, we constructed a H-rGO-Pt@Pd NPs with the characteristics of glucose oxidase. Then, the H-rGO-Pt@Pd NPs and Au NPs was modified on the surface of screen printed electrode to form an enzyme-free glucose biosensor. Among them, H-rGO-Pt@Pd NPs/Au NPs has a strong ability to capture electrons and catalyze the hydrolysis of glucose, resulting in a current-time change. The i-t curve is used to record the current-time change under different glucose concentration. When the glucose concentration was in the range of 0.6-1.4 mg/mL, the sensor current response value (Y) showed a linear relationship with the glucose concentration (X). The linear regression equation was Y=4.8515X-9.9361, the correlation coefficient was 0.9844, and the minimum detection limit was 0.2 mg/mL. In addition, the sensor has good specificity and stability.
Research on On-line Identification of Equivalent Circuit Model Parameters and SOC Estimation for Lithium-ion Batteries
Authors: Feng Juqiang , Si Yuwen , Huang Kaifeng , Lu Jun , Zhang Xing 
Published: August 2021

Abstract
The online identification model parameters can reflect the real terminal voltage state of the battery in real time and provide accurate observation data for battery SOC estimation. BMS is an important part of new energy vehicles, which supervises and controls the working process of the battery. The core of BMS is SOC estimation, and the accuracy of its estimation is related to whether the battery works efficiently and safely. Based on Thevenin model, FFRLS-EKF and KF-EKF were used to estimate the SOC of ternary lithium battery under DST condition. The estimation results show that FFRLS-EKF has a maximum error of 0.0079, which can estimate the SOC of the battery well.
Highly electrically conductive silver-coated poly(p-phenylene terephthalamide) fiber prepared by poly(catechol/polyamine) surface modification
Authors: Hao Mingzheng , Zhou Yang , Tian Zejin , Li Zixuan , Song Wenqiang , Wang Jiazhen , Lyu Chao 
Published: August 2021

Abstract
In this work, poly(p-phenylene terephthalamide)(PPTA) fiber was modified by catechol and tetraethylenepentamine through Michael addition and Schiff base reaction. Then the silver-coated PPTA fiber was prepared by electroless plating. The SEM images showed that the phenolic hydroxyl group of catechol has a strong adhesion effect and a metal binding ability, which can make the silver particles tightly coated on the surface of PPTA fiber. The XPS and XRD results indicate that the Ag on the surface of the PPTA fiber is elemental silver, and there is no diffraction peaks of silver halide and silver oxide. The resistivity of the silver-coated PPTA fiber prepared with the deposition time of 2h has reached 0.1m^cm. This highly conductive PPTA/Ag fiber can be used in the field of flexible conductive materials and electromagnetic shielding clothing.
Age Differences in Multimodal Quantitative Sensory Testing and Associations With Brain Volume
Authors: Johnson Alisa J , Wilson Abigail T , Laffitte Nodarse Chavier , Montesino-Goicolea Soamy , Valdes-Hernandez Pedro A , Somerville Jessie , Peraza Julio A , Fillingim Roger B , Bialosky Joel , Cruz-Almeida Yenisel 
Published: August 2021

Abstract

Background and Objectives
Somatosensory function is critical for successful aging. Prior studies have shown declines in somatosensory function with age; however, this may be affected by testing site, modality, and biobehavioral factors. While somatosensory function declines are associated with peripheral nervous system degradation, little is known regarding correlates with the central nervous system and brain structure in particular. The objectives of this study were to examine age-related declines in somatosensory function using innocuous and noxious stimuli, across 2 anatomical testing sites, with considerations for affect and cognitive function, and associations between somatosensory function and brain structure in older adults.

Research Design and Methods
A cross-sectional analysis included 84 “younger” (n = 22, age range: 19–24 years) and “older” (n = 62, age range: 60–94 years) healthy adults who participated in the Neuromodulatory Examination of Pain and Mobility Across the Lifespan study. Participants were assessed on measures of somatosensory function (quantitative sensory testing), at 2 sites (metatarsal and thenar) using standardized procedures, and completed cognitive and psychological function measures and structural magnetic resonance imaging.

Results
Significant age × test site interaction effects were observed for warmth detection (p = .018, ηp2= 0.10) and heat pain thresholds (p = .014, ηp2= 0.12). Main age effects were observed for mechanical, vibratory, cold, and warmth detection thresholds (ps &lt; .05), with older adults displaying a loss of sensory function. Significant associations between somatosensory function and brain gray matter structure emerged in the right occipital region, the right temporal region, and the left pericallosum.

Discussion and Implications
Our findings indicate healthy older adults display alterations in sensory responses to innocuous and noxious stimuli compared to younger adults and, furthermore, these alterations are uniquely affected by anatomical site. These findings suggest a nonuniform decline in somatosensation in older adults, which may represent peripheral and central nervous system alterations part of aging processes.
Long-Term Safety and Efficacy of the Anti-Mucosal Addressin Cell Adhesion Molecule-1 Monoclonal Antibody Ontamalimab (SHP647) for the Treatment of Crohn’s Disease: The OPERA II Study
Authors: D’Haens Geert R , Reinisch Walter , Lee Scott D , Tarabar Dino , Louis Edouard , Kłopocka Maria , Klaus Jochen , Schreiber Stefan , Il Park Dong , Hébuterne Xavier , Nagy Peter , Cataldi Fabio , Martin Steven W , Nayak Satyaprakash , Banerjee Anindita , Gorelick Kenneth J , Sandborn William J 
Published: August 2021

Abstract

Background
Patients with Crohn’s disease (CD) experience intestinal inflammation. Ontamalimab (SHP647), a fully human immunoglobulin G2 monoclonal antibody against mucosal addressin cell adhesion molecule-1, is a potential novel CD treatment. OPERA II, a multicenter, open-label, phase 2 extension study, assessed the long-term safety and efficacy of ontamalimab in patients with moderate-to-severe CD.

Methods
Patients had completed 12 weeks of blinded treatment (placebo or ontamalimab at 22.5, 75, or 225 mg subcutaneously) in OPERA (NCT01276509) or had a clinical response to ontamalimab 225 mg in TOSCA (NCT01387594). Participants received ontamalimab at 75 mg every 4 weeks (weeks 0–72), then were followed up every 4 weeks for 24 weeks. One-time dose reduction to 22.5 mg or escalation to 225 mg was permitted at the investigator’s discretion. The primary end points were safety and tolerability outcomes. Secondary end points included changes in serum drug and biomarker concentrations. Efficacy end points were exploratory, and used non-responder imputation methods.

Results
Overall, 149/268 patients completed the study. The most common adverse event leading to study discontinuation was CD flare (19.8%). Two patients died; neither death was considered to be drug related. No dose reductions occurred; 157 patients had their dose escalated. Inflammatory biomarker concentrations decreased. Serum ontamalimab levels were consistent with known pharmacokinetics. Remission rates (Harvey-Bradshaw Index [HBI] ≤ 5; baseline, 48.1%; week 72, 37.3%) and response rates (baseline [decrease in Crohn’s Disease Activity Index ≥ 70 points], 63.1%; week 72 [decrease in HBI ≥ 3], 42.5%) decreased gradually.

Conclusions
Ontamalimab was well tolerated; treatment responses appeared to be sustained over 72 weeks.
ClinicalTrials.gov ID: NCT01298492.
CD4+ T cells in inflammatory diseases: pathogenic T-helper cells and the CD69–Myl9 system
Authors: Nakayama Toshinori , Hirahara Kiyoshi , Kimura Motoko Y , Iwamura Chiaki , Kiuchi Masahiro , Kokubo Kota , Onodera Atsushi , Hashimoto Kahoko , Motohashi Shinichiro 
Published: August 2021

Abstract
CD4+ T cells not only direct immune responses against infectious micro-organisms but are also involved in the pathogenesis of inflammatory diseases. In the last two to three decades, various researchers have identified and characterized several functional CD4+ T-cell subsets, including T-helper 1 (Th1), Th2, Th9 and Th17 cells and regulatory T (Treg) cells. In this mini-review, we introduce the concept of pathogenic Th cells that induce inflammatory diseases with a model of disease induction by a population of pathogenic Th cells: the ‘pathogenic Th population disease-induction model’. We will focus on Th2 cells that induce allergic airway inflammation—pathogenic Th2 cells (Tpath2 cells)—and discuss the nature of Tpath2 cells that shape the pathology of chronic inflammatory diseases. Various Tpath2-cell subsets have been identified and their unique features are summarized in mouse and human systems. Second, we will discuss how Th cells migrate and are maintained in chronic inflammatory lesions. We propose a model known as the ‘CD69–Myl9 system’. CD69 is a cell surface molecule expressed on activated T cells and interaction with its ligand myosin light chain 9 (Myl9) is required for the induction of inflammatory diseases. Myl9 molecules in the small vessels of inflamed lungs may play a crucial role in the migration of activated T cells into inflammatory lesions. Emerging evidence may provide new insight into the pathogenesis of chronic inflammatory diseases and contribute to the development of new therapeutic strategies for intractable inflammatory disorders.
Impact of four fiber-rich supplements on nutrient digestibility, colostrum production, and farrowing performance in sows
Authors: Feyera Takele , Hu Liang , Eskildsen Maria , Bruun Thomas S , Theil Peter K 
Published: August 2021

Abstract
This study aimed to investigate the impact of dietary fiber (DF) sources on sow and litter performance, and apparent total tract digestibility (ATTD) of gross energy (GE) and nutrients. A total of 48 sows were stratified for body weight at mating and randomly assigned to one of four DF sources (mixed fiber [MF], palm kernel expellers [PKE], sugar beet pulp [SBP], or soy hulls [SH]) and fed the diet from mating until farrowing. Within DF treatments, sows were supplemented with one of two extra energy sources (glycerol or sugar dissolved in water), whereas a third group (control) received water from day 108 of gestation until farrowing. The number of total born, live-born, and stillborn pigs; birth time and birth weight of the pigs; farrowing duration; and farrowing assistance (FA) were recorded. Live-born pigs were weighed again at 12 and 24 h after birth to record weight gain, which was used to estimate intake and yield of colostrum. Blood samples were collected once daily from day −3 relative to farrowing until day 1 after farrowing in sows and once from selected pigs right after birth. Fecal samples were collected on day 114 of gestation and colostrum at 0, 12, 24, and 36 h after onset of farrowing. Intake of soluble and insoluble nonstarch polysaccharides (NSP) was greater for SBP (P &lt; 0.001) and PKE (P &lt; 0.001) supplemented sows, respectively, when compared with other groups. Farrowing duration and stillbirth rate were not affected by DF sources, but PKE and SH supplemented sows had greater FA than SBP and MF supplemented sows (P &lt; 0.001). Extra energy supplement did not improve the farrowing performance. Concentration (P = 0.02) and output (P = 0.04) of dry matter in colostrum, and ATTD of GE (P &lt; 0.001) and crude protein (CP; P &lt; 0.001) were lower for PKE supplemented sows than in sows from the remaining groups. Intake of insoluble NSP correlated negatively with ATTD of GE (P &lt; 0.001) and CP (P &lt; 0.001). Concentrations of glucose (P &lt; 0.001), lactate (P &lt; 0.001), CO2 (P &lt; 0.001), and HCO3 (P &lt; 0.001) in sows blood were increased with time progress relative to farrowing. Newborn pigs from PKE supplemented sows had greater concentration of lactate (P = 0.02) and lower blood pH (P = 0.02) than the remaining treatments. In conclusion, PKE supplement reduced ATTD of GE and CP, and concentration and output of dry matter in colostrum but increased FA. Results of this experiment indicated that the use of PKE as a fiber source for late gestating sows should be avoided.
Association of Female Genital Schistosomiasis With the Cervicovaginal Microbiota and Sexually Transmitted Infections in Zambian Women
Authors: Sturt Amy S , Webb Emily L , Himschoot Lisa , Phiri Comfort R , Mapani Joyce , Mudenda Maina , Kjetland Eyrun F , Mweene Tobias , Levecke Bruno , van Dam Govert J , Corstjens Paul L A M , Ayles Helen , Hayes Richard J , van Lieshout Lisette , Hansingo Isaiah , Francis Suzanna C , Cools Piet , Bustinduy Amaya L 
Published: August 2021

Abstract

Background
The cervicovaginal microbiota, including sexually transmitted infections (STIs), have not been well described in female genital schistosomiasis (FGS).

Methods
Women (aged 18–31, sexually active, nonpregnant) were invited to participate at the final follow-up of the HPTN 071 (PopART) Population Cohort in January–August 2018. We measured key species of the cervicovaginal microbiota (Lactobacillus crispatus, L. iners, Gardnerella vaginalis, Atopobium vaginae, and Candida) and STIs (Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, and Mycoplasma genitalium) using quantitative PCR (qPCR). We evaluated associations of the microbiota and STI presence and concentration with FGS (qPCR-detected Schistosoma DNA in any of 3 genital specimens).

Results
The presence and concentration of key cervicovaginal species did not differ between participants with (n = 30) or without FGS (n = 158). A higher proportion of participants with FGS had T. vaginalis compared with FGS-negative women (P = .08), with further analysis showing that T. vaginalis was more prevalent among women with ≥2 Schistosoma qPCR-positive genital specimens (50.0%, 8/16) than among FGS-negative women (21.5%, 34/158; P = .01).

Conclusions
We found weak evidence of an association between the presence of T. vaginalis and FGS, with a stronger association in women with a higher-burden FGS infection. Additional research is needed on potential between-parasite interactions, especially regarding HIV-1 vulnerability.
The Clinical Pause: An Augmented Approach to Simulation Debriefing in Nursing Education
Authors: Kacalek Cathy , Krautscheid Lorretta , Walkley Vanessa 
Published: August 2021

Abstract
Debriefing after simulation, a form of reflection-on-action, is widely practiced in nursing education. A lesser used alternative is a faculty-facilitated clinical pause. During natural breaks within an unfolding simulation scenario, faculty incorporated Caputi’s thinking skills to facilitate clinical reasoning, reflection-in-action, and timely feedback. The clinical pause enabled well-timed validation of correct thinking, resolution of erroneous thinking, and deliberate practice opportunities to construct contextual meaning. Written student comments, obtained after the simulation, suggest the clinical pause teaching innovation enhanced learning and clinical reasoning. Combining the clinical pause with end-of-simulation debriefing can provide a powerful one-two punch that maximizes clinical judgment.