bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of entrepreneurial orientation, organizational learning capability and service innovation in organizational performance
Authors: Gomes Giancarlo , Seman Laio Oriel , Berndt Ana Clara , Bogoni Nadia 
Published: August 2021

PurposeThe purpose of this study is to analyze the relationships between Entrepreneurial Orientation, Organizational Learning Capability, Service Innovation and Organizational Performance. To this end, it was sought to analyze the mediating role of organizational learning capability and service innovation within entrepreneurial orientation and organizational performance relationship in knowledge-intensive organizations.Design/methodology/approachThe sample consisted of 159 architecture and urbanism companies from Santa Catarina, Brazil. The study opted to use managers as key informants since they are the ones that have general information about the organization and are a valuable source for assessing the different variables of the organization. For data analysis, the PLS-PM algorithm (Partial Least Squares Path Modeling) was used.FindingsResults showed that entrepreneurial orientation is a strong driver of service innovation and organizational performance. Organizational learning capability acts as a facilitator of innovation and has a positive influence on organizational performance. Another theoretical contribution of this study to organizational learning capability is the confirmation of its mediation in service innovation and organizational performance. Management needs to make its organization more proactive and creative, continually promoting new ideas. Architecture and urbanism organizations should pay more attention to maintaining and promoting entrepreneurial orientation permanently. The trend toward both proactivity and risk-taking can be an inherent advantage of these knowledge-intensive business services.Originality/valueFew studies have explored the mediating role of organizational learning capability and service innovations in organizational performance. In particular, the combined effects of entrepreneurial orientation and organizational learning capability have been neglected by the knowledge-intensive organizations literature. The study is justified by providing a more complete view of the relationship between entrepreneurial orientation and the performance of knowledge-intensive organizations, highlighting the role of organizational learning capability and performance in service innovation.
Mito‐targeted antioxidant prevents cardiovascular remodelling in spontaneously hypertensive rat by modulation of energy metabolism
Authors: Potnuri Ajay Godwin , Purushothaman Sreeja , Saheera Sherin , Nair Renuka R. 
Published: August 2021

AbstractHypertension induced left ventricular hypertrophy (LVH) augments the risk of cardiovascular anomalies. Mitochondrial alterations result in oxidative stress, accompanied by decrease in fatty acid oxidation, leading to the activation of the hypertrophic program. Targeted antioxidants are expected to reduce mitochondrial reactive oxygen species more effectively than general antioxidants. This study was designed to assess whether the mito‐targeted antioxidant, Mito‐Tempol (Mito‐TEMP) is more effective than the general oxidant, Tempol (TEMP) in reduction of hypertension and hypertrophy and prevention of shift in cardiac energy metabolism. Spontaneously hypertensive rats were administered either TEMP (20 mg/kg/day) or Mito‐TEMP (2 mg/kg/day) intraperitoneally for 30 days. Post treatment, animals were subjected to 2D‐echocardiography. Myocardial lysates were subjected to RPLC – LTQ‐Orbitrap‐MS analysis. Mid‐ventricular sections were probed for markers of energy metabolism and fibrosis. The beneficial effect on cardiovascular structure and function was significantly higher for Mito‐TEMP. Increase in mitochondrial antioxidants and stimulation of fatty acid metabolism; with significant improvement in cardiovascular function was apparent in spontaneously hypertensive rats (SHR) treated with Mito‐TEMP. The study indicates that Mito‐TEMP is superior to its non‐ targeted isoform in preventing hypertension induced LVH, and the beneficial effects on heart are possibly mediated by reversal of metabolic remodelling.
Relation between carotid intimal medial thickness and left ventricular mass and left ventricular mass indices in maintenance hemodialysis patients
Authors: Bahie Ahmed , El‐Said Ghada , Abd El Wahab Ahmed M. 
Published: August 2021

AbstractLeft ventricular hypertrophy (LVH) is a risk factor of cardiovascular morbidity in dialysis patients. The association between LV mass and carotid intimal medial thickness (CIMT) could be due to increased hemodynamic load in dialysis patients. The relationship between CIMT and LVM indices in hemodialysis (HD) patients was investigated. This is a cross‐sectional study including 65 HD patients, divided into two groups: Group 1 with CIMT ≤ 1 mm (N = 29), Group 2 with CIMT > 1 mm (N = 36). Echocardiographic evaluation of the LVM, CIMT measurement using B‐mode ultrasonography, patients' basic clinical and biochemical data were recorded. Patients with CIMT > 1 mm (Group 2) showed significantly higher LVM, LVM/BSA (body surface area), and LVM/Ht2.7 (height). Regarding linear regression, CIMT was found to be an independent predictor for LVM, LVM/BSA, and LVM/Ht2.7. LVM, LVMI, and LVM/Ht2.7 are significantly elevated in HD patients with CIMT > 1 mm group. CIMT was found to be the independent predictor for LVH in maintenance HD patients.
Prognostic value of beta‐2 microglobulin on mortality in chronic kidney disease patients: A systematic review and meta‐analysis
Authors: Zhang Jialing , Lu Xiangxue , Zu Yuan , Li Han , Wang Shixiang 
Published: August 2021

AbstractThe aim of this study was to delve into whether beta‐2 microglobulin could assess all‐cause mortality in patients with chronic kidney disease. PubMed and Embase were systematically searched. Hazard risk and 95% CI were pooled using random‐effect models. A total of eight studies were involved according to the inclusion and exclusion criterions. By meta‐analysis, each 1 mg/L increase in beta‐2 microglobulin displayed positive relationships to the risk of all‐cause mortality (hazard risk 1.03, 95% CI = 1.02–1.03) and cardiovascular events (hazard risk 1.04, 95% CI = 1.00–1.08) in patients with dialysis. However, the relationship between elevated level of serum beta‐2 microglobulin as a categorical variable and mortality was not significant. The prognostic value of elevated beta‐2 microglobulin might be significant in ESRD patients with dialysis and a proper cutoff value to predict mortality should be determined in the future.
Adiposity in schizophrenia: A systematic review and meta‐analysis
Authors: Smith Emily , Singh Raghunath , Lee Jiwon , Colucci Laura , Graff‐Guerrero Ariel , Remington Gary , Hahn Margaret , Agarwal Sri Mahavir 
Published: August 2021

AbstractObjectiveAlthough a relationship between schizophrenia (SCZ), antipsychotic (AP) medication, and metabolic dysregulation is now well established, the effect of adiposity is less well understood. By synthesizing findings from imaging techniques that measure adiposity, our systematic review and meta‐analysis (PROSPERO CRD42020192977) aims to determine the adiposity‐related effects of illness and treatment in this patient population.MethodsWe searched MEDLINE, EMBASE, PsychINFO and Scopus for all relevant case‐control and prospective longitudinal studies from inception until February 2021. Measures of adiposity including percent body fat (%BF), subcutaneous adipose tissue (SAT), and visceral adipose tissue (VAT) were analyzed as primary outcomes.ResultsOur search identified 29 articles that used imaging methods to quantify adiposity among patients with SCZ spectrum disorders. Analyses revealed that patients have greater %BF (mean difference (MD) = 3.09%; 95% CI: 0.75–5.44), SAT (MD = 24.29 cm2; 95% CI: 2.97–45.61) and VAT (MD = 33.73 cm2, 95% CI: 4.19–63.27) compared to healthy controls. AP treatment was found to increase SAT (MD = 31.98 cm2; 95% CI: 11.33–52.64) and VAT (MD = 16.30 cm2; 95% CI: 8.17–24.44) with no effect on %BF. However, change in %BF was higher for AP‐free/AP‐naïve patients compared to treated patients.ConclusionOur findings indicate that patients with SCZ spectrum disorders have greater adiposity than healthy controls, which is increased by AP treatment. Young, AP‐naïve patients may be particularly susceptible to this effect. Future studies should explore the effect of specific APs on adiposity and its relation to overall metabolic health.
Food insecurity risk and alcohol use disorder in US young adults: Findings from the National Longitudinal Study of Adolescent to Adult Health
Authors: Nagata Jason M. , Whittle Henry J. , Ganson Kyle T. , Tabler Jennifer , Hahn Judith A. , Weiser Sheri D. 
Published: August 2021

AbstractBackground and ObjectivesThe relationship between food insecurity and alcohol use disorder remains unknown. The aim of this study was to determine the association between food insecurity risk and alcohol use disorder in a nationally representative sample of young adults.MethodsCross‐sectional nationally representative data of 14,786 US young adults aged 24–32 years old from Wave IV (2008) of the National Longitudinal Study of Adolescent to Adult Health were analyzed to assess a single‐item measure of food insecurity risk and Diagnostic and Statistical Manual, 5th Edition (DSM‐5) alcohol use disorder.ResultsAmong young adults, 12% were found to be at risk for food insecurity. Young adults with food insecurity risk had greater odds of moderate (adjusted odds ratio [AOR]: 1.34, 95% confidence interval [CI]: 1.13–1.58) and severe (AOR: 1.67, 95% CI: 1.34–2.07) threshold alcohol use disorder than food‐secure young adults, adjusting for age, sex, race/ethnicity, education, income, receipt of public assistance, household size, and smoking. Food insecurity risk was also associated with a 23% higher (95% CI: 11%–37%) number of problematic alcohol use behaviors (e.g., risky behaviors, continued alcohol use despite emotional or physical health problems).Discussion and ConclusionsFood insecurity risk is associated with problematic patterns of alcohol use. Health care providers should screen for food insecurity and problematic alcohol use in young adults and provide referrals for further resources and treatment when appropriate.Scientific SignificanceThis nationally representative study of US young adults is the first to find an association between food insecurity risk and alcohol use disorder using DSM‐5 criteria.
Clinical correlates of drug‐related dreams in opioid use disorder
Authors: Ellis Jennifer D. , Mayo Jami L. , Finan Patrick H. , Gamaldo Charlene E. , Huhn Andrew S. 
Published: August 2021

AbstractBackground and ObjectivesDrug‐related dreams are commonly reported by individuals in treatment for substance use disorders, which may be distressing. Existing evidence suggests that dream recollection may be influenced by clinically relevant phenomena, such as opioid use and withdrawal, general sleep disturbance, affective symptoms, and chronic pain. However, very few studies have explored drug‐related dreams among individuals who screened positive for opioid use disorder (OUD).MethodsAdults recruited from Amazon Mechanical Turk (MTurk) who screened positive for OUD (N = 154) completed a questionnaire about drug‐related dreams, as well as measures assessing sleep, opioid use history, stress, anxiety, and chronic pain. χ2 analyses, one‐way analysis of variance, and bivariate correlations, correcting for the false discovery rate, were used as appropriate to explore correlates of (1) recollecting a drug‐related dream, and (2) experiencing post‐dream craving and distress.ResultsIndividuals who recollected a past‐week drug‐related dream were more likely to report other recent sleep disturbances, including poorer sleep quality, greater insomnia symptoms, and a higher risk for sleep apnea. Post‐dream craving and distress were both associated with greater insomnia symptoms, poor sleep hygiene behaviors, and greater anxiety symptoms. Individuals who had ever experienced a drug‐related dream (recently, or in their lifetime) were more likely to report a history of severe withdrawal, overdose, and intravenous opioid use.Conclusion and Scientific SignificanceDrug‐related dreams were common among individuals in the present sample and were related to other clinically relevant phenomena. Interventions that treat co‐occurring OUD, pain, sleep symptoms, and affective symptoms may improve overall well‐being in this population.
The “New Urban Poor” Identity: Evidence from China
Authors: Tong Chen 
Published: August 2021

AbstractHigher education can play a crucial role in shaping one’s social identity, and a diploma from a prestigious institution has a positive effect on a person’s social status. However, the expansion of college enrollment in 1999 in China weakened the capacity of a college diploma to confer on graduates a distinct identity as someone of high standing. For youth from rural backgrounds, higher education was once the most important channel for upward social mobility. As the social value of a college diploma has declined, most college graduates from rural backgrounds have been assigned a new identity: the “new urban poor” (NUP). This article discusses the construction and characteristics of the NUP identity in China, using evidence from television series.
Representation of Caste and Class in Modern Tamil Films
Authors: Rajapandian Radha , Dhanapal Bharathi , Iyyanar Sivakumar 
Published: August 2021

AbstractFilms are fictional accounts that can easily serve as an opiate for an enormous number of people who rely on this medium to help them escape from the world. However, films also influence people's cultural and social values. For example, Indian films constantly depict caste, class, and gender disparities, but they do so in ways that reinforce social stigmas instead of challenging them. This essay examines three Tamil‐language films—Pariyerum Perumal, Asuran, and Karnan—that definitely challenge the status quo. These films reflect the importance of symbolic and cultural markers of discrimination according to caste and class. Through the use of many stereotypical characters, films dealing with social problems demonstrate the ways in which objectification, exclusion, and silence all play a role in perpetuating systems of domination. In this way, Indian films show destructive patterns and shed light on how to stop discriminatory practices.
The Marginalization of Migrant Workers Reflected in Chinese Movies and TV
Authors: Ke Jinhua , Fu Xiaofeng , Hu Rong 
Published: August 2021

AbstractThe new class of migrant workers that emerged in the late 1980s in China has been an important driving force for the modernization and urbanization of China. However, mainly due to the polarization between the rich and the poor, the contrast between urban and rural areas, and the reorganization of social strata caused by the development of the market economy, these migrant workers have been seriously marginalized. Against this social backdrop, a series of contemporary Chinese films and TV plays have attempted to honestly depict the daily lives of migrant workers and have used different perspectives to illustrate the social barriers they face. This has aroused the public’s attention to the problems faced by migrant workers and also provided us with helpful ideas to solve them. This article selects three representative works, one TV play and two movies, to discuss this issue.
Characterizing the stimulation interference in electroencephalographic signals during brain–computer interface–controlled functional electrical stimulation therapy
Authors: Jovanovic Lazar I. , Popovic Milos R. , Marquez‐Chin Cesar 
Published: August 2021

AbstractIntroductionThe integration of brain–computer interface (BCI) and functional electrical stimulation (FES) has brought about a new rehabilitation strategy: BCI‐controlled FES therapy or BCI‐FEST. During BCI‐FEST, the stimulation is triggered by the patient’s brain activity, often monitored using electroencephalography (EEG). Several studies have demonstrated that BCI‐FEST can improve voluntary arm and hand function after an injury, but few studies have investigated the FES interference in EEG signals during BCI‐FEST. In this study, we evaluated the effectiveness of band‐pass filters, used to extract the BCI‐relevant EEG components, in simultaneously reducing stimulation interference.MethodsWe used EEG data from eight participants recorded during BCI‐FEST. Additionally, we separately recorded the FES signal generated by the stimulator to estimate the spectral components of the FES interference, and extract the noise in time domain. Finally, we calculated signal‐to‐noise ratio (SNR) values before and after band‐pass filtering, for two types of movements practiced during BCI‐FEST: reaching and grasping.ResultsThe SNR values were greater after filtering across all participants for both movement types. For reaching movements, mean SNR values increased between 1.31 dB and 36.3 dB. Similarly, for grasping movements, mean SNR values increased between 2.82 dB and 40.16 dB, after filtering.ConclusionsBand‐pass filters, used to isolate EEG frequency bands for BCI application, were also effective in reducing stimulation interference. In addition, we provide a general algorithm that can be used in future studies to estimate the frequencies of FES interference as a function of the selected stimulation pulse frequency, FSTIM, and the EEG sampling rate, FS.
Heterogeneous indications and the need for viability assessment: An international survey on the use of machine perfusion in liver transplantation
Authors: Patrono Damiano , Cussa Davide , Rigo Federica , Romagnoli Renato ,   the Liver Machine Perfusion Survey Group
Published: August 2021

AbstractAlthough machine perfusion (MP) is being increasingly adopted in liver transplantation, indications, timing, and modality are debated. To investigate current indications for MP a web‐based Google Forms survey was launched in January 2021 and addressed to 127 experts in the field, identified among first and corresponding Authors of MP literature in the last 10 years. The survey presented 10 real‐life cases of donor–recipient matching, asking whether the liver would be accepted (Q1), whether MP would be used in that particular setting (Q2) and, if so, by which MP modality (Q3) and at what timing during preservation (Q4). Respondents could also comment on each case. The agreement was evaluated using Krippendorff's alpha coefficient. Answers from 39 (30.1%) participants disclosed significant heterogeneity in graft acceptance, MP indications, technique, and timing. Agreement between respondents was generally poor (Q1, α = 0.11; Q2, α = 0.14; Q3, α = 0.12, Q4, α = 0.11). Overall, respondents preferred hypothermic MP and an end‐ischemic approach in 56.3% and 81.1% of cases, respectively. A total of 18 (46.2%) participants considered only one MP approach, whereas 17 (43.6%) and 3 (7.7%) considered using alternatively 2 or 3 different techniques. Of 38 comments, 17 (44.7%) were about the use of MP for graft viability assessment before implantation. This survey shows considerable variability in MP indications, emphasizing the need to identify scenarios of optimal utilization for each technique. Viability assessment emerges as a fundamental need of transplant professionals when considering the use of MP.
Corruption and social trust: The role of corporate social responsibility
Authors: Thanetsunthorn Namporn 
Published: August 2021

AbstractThe importance and benefits of social trust have widely been recognized in the literature. However, there has been increasing concern about corruption in relation to a decline in social trust, and the role of business in this relationship remains largely unknown. This study aims to examine the linkages among corruption, corporate social responsibility (CSR), and social trust. Using a large sample of 6892 corporations from 33 countries over the period 2010–2014, the results demonstrate that corruption generates a highly eroding effect on social trust, whereas CSR has important implications for promoting trust among people in society. The results further suggest the potential role of CSR in mitigating the eroding effect of corruption on social trust. These results are robust across various methods of estimation, falsification tests, and in a different time period (2017–2020). This study makes several contributions to the literature both theoretically and empirically, and offers meaningful implications for businesses and policymakers.
Towards conjoint solidarity in healthcare
Authors: O'Neill Jennifer 
Published: August 2021

AbstractSolidarity remains an ambiguous concept despite the long political tradition pertaining to concepts of fraternity, togetherness and collective values or goals. In healthcare ethics, it has been under‐explored, perhaps due to the perception that it opposes individual autonomy. However, even where autonomy is interpreted as a liberal construct, the solidaristic act may be borne out of free choice, rather than stand in opposition to it. To complement the existing scholarship, the concept of ‘conjoint solidarity’ in healthcare is proposed. Conjoint solidarity may be defined as 'the shared goal of all healthcare stakeholders (encapsulating all healthcare practitioners and service users) to accept or adopt a duty to assist one another to achieve improved healthcare outcomes’. The practical application of both medical autonomy and conjoint solidarity is through the process of shared decision making. An epistemic approach may be applied to ‘pool information’ from healthcare practitioners and patients to determine what improved healthcare outcomes are. This collective approach may also serve to address healthcare issues such exclusion, othering, paternalism and conflict of interest. Furthermore, in extending this relational approach to justice, consideration may be given to how improved healthcare may be attained in a manner that allows patients to also play their part. To this end, medical autonomy, conjoint solidarity and relational distributive justice may be considered interdependent constructs, which, when fully utilized, may help improve healthcare.
Reducing subspace models for large‐scale covariance regression
Authors: Franks Alexander M. 
Published: August 2021

AbstractWe develop an envelope model for joint mean and covariance regression in the large p, small n setting. In contrast to existing envelope methods, which improve mean estimates by incorporating estimates of the covariance structure, we focus on identifying covariance heterogeneity by incorporating information about mean‐level differences. We use a Monte Carlo EM algorithm to identify a low‐dimensional subspace that explains differences in both means and covariances as a function of covariates, and then use MCMC to estimate the posterior uncertainty conditional on the inferred low‐dimensional subspace. We demonstrate the utility of our model on a motivating application on the metabolomics of aging. We also provide R code that can be used to develop and test other generalizations of the response envelope model.