bluuebunny/crossref_metadata_2025_split huggingface dataset:
Giardiasis and post-infectious bowel syndrome
Authors: Belova A. A. , Shestakova M. D. , Khavkin A. I. 
Published: July 2021

Post-infectious irritable bowel syndrome — one of the most frequent conditions diagnosed in pediatric gastroenterological practice. According to numerous research parisitosis contributes to the chronology of gastrointestinal tract pathology. it is known that the infection Lamblia intestinalis can increase the risk of developing post-infectious IBS, changing species composition and diversity of the intestinal microbiota, modulating metabolism of the host, the nature of the immune response and adversely affecting the mucosal barrier and the motility of the digestive tract. Importantly, the prevalence of giardiasis in patients with symptoms of IBS and dyspepsia at the moment, it remains at a high level. Further research into the pathogenesis of Lamblia intestinalis infection in patients with IBS will be of great importance in medicine.
Algorithm for diagnosing the latent form of celiac disease in adults
Authors: Fedorenko S. V. , Kovaleva E. G. , Grankina O. G. , Levina T. P. , Chumel A. N. 
Published: July 2021

The article presents a clinical case of the latent course of celiac disease with diagnosis in the adult period, reflects the role of trigger factors, the features of the clinical course, the formation of concomitant lactase deficiency and the need for all diagnostic stages for diagnosis.
Microbiome, probiotics, and COVID-19: promising approaches to support innate and acquired immunity systems
Authors: Gromova O. A. , Torshin I. Yu. , Chuchalin A. G. , Maksimov V. A. 
Published: July 2021

The gut microbiome is the main source of microorganisms for the formation of microbiomes of other organs and tissues. Dysbiosis of the intestine and lungs associated with COVID-19 leads to an increase in inflammatory reactions and stimulates the development of a cytokine storm through an increase in the activity of toll receptors. The patient’s intestinal dysbiosis facilitates the invasion of coronaviruses and intensifies inflammatory responses. Conversely, the progression of COVID-19 leads to increased dysbiosis in both the lungs and the intestines. Improving the microbiome through probiotic strains of bifido / lactobacilli and prebiotic substances is an important approach to mitigate the “wave” of COVID-19 at the population level.
LA OBESIDAD Y COVID-19
Authors: Vásquez Hazel Anderson 
Published: July 2021

A principios de diciembre 2019, surgió en Wuhan, Provincia de Hubei China una enfermedad causada por un nuevo Coronavirus 2019 (2019-nCoV-2) también denominado SARS-CoV-2 (síndrome respiratorio agudo severo tipo-2). La Organización Mundial de la Salud (OMS) declaró la enfermedad por coronavirus 2019 (COVID-19) como pandemia el 11 de marzo de 2020, hasta enero 2021 se han confirmado más de 22.400.000 casos de infección por SARS-CoV-2 en 216 países y se ha reportado más de 788.000 muertes (1). Richardson y cols. (2) en un estudio de casos con 5.700 pacientes con COVID-19 ingresados en 12 hospitales de la Ciudad de Nueva York (marzo-abril 2020), mostró que el 41,7% de los sujetos presentó obesidad. Según la OMS la tasa de mortalidad por infección de COVID-19 es de 0,5-1% (3).

El COVID-19 puede presentar un amplio espectro clínico, desde infecciones asintomáticas y leves hasta complicaciones del tracto respiratorio superior y neumonía; entre las manifestaciones extra-respiratorias puede incluir complicaciones cardíacas, disfunción renal, trastornos gastrointestinales, neurológicos y hematológicos. Otras condiciones clínicas en el obeso son la enfermedad obstructiva crónica, la enfermedad cardiovascular crónica, hipertensión, diabetes y enfermedad cerebrovascular (4).
Leishmaniasis en el Ecuador: revisión bibliográfica
Authors: Toalombo Espin Christian Javier , Coque Procel Mariela 
Published: July 2021

Introducción: Leishmaniasis es parte de las nueve enfermedades tropicales más importantes a nivel mundial, debido a su morbilidad y mortalidad. Registrándose de 1.5 a 2 millones de casos nuevos al año, considerándose un problema de salud pública grave.
Objetivo: Realizar una revision bibliográfica con la finalidad de actualizar los conocimientos de los profesionales de la salud del país, sobre leishmaniasis
Materiales y Métodos: Revisión sistemática de artículos publicados en revistas indexadas, a través de la base de datos: GPC- NICE, PubMed, Science Direct, Elsevier, SciELO, Biblioteca virtual de Salud PAHO.
Resultados: Se ha registrado 800 especies de mosca de arena en el mundo, de las cuales un 10% transmiten una especie particular del parásito protozoario del género Leishmania. En el Ecuador el parásito se encuentra presente en 22 de las 24 provincias, con un reporte de 6608 casos entre el año 2010-2014. Registrándose un aumento de casos, a 21305 en el año 2016. El diagnóstico de dicha enfermedad se lleva a cabo a través de un examen microscópico de frotis o aspirado de úlceras cutánea. Con respecto al tratamiento, el Ministerio de Salud Pública del Ecuador utiliza el antimoniato de meglumina como primera opción terapéutica, a una dosis de 10 – 15 mg/kg/día.
Conclusiones: El personal de salud debe ser capacitado para reconocer la zoonosis en su primera etapa, tratarlos oportunamente y evitar errores diagnósticos. Así como iniciar el tratamiento acorde con los parámetros dispuestos, esperando que la evolución de los pacientes sea favorable.
Tendencias epidemiológicas del cáncer de tiroides en la zona centro de Ecuador en el periodo 2012-2016
Authors: Sánchez Miño Jorge Isaac , Batista Castro Zenia , García Barceló María De la Caridad , Proaño Alulema Ricardo Xavier , Salazar Garcés Dolores Krupskaya , García Orozco Lucas , Aguilar Salazar Aida Fabiola 
Published: July 2021

Introducción: la relevante incidencia mundial y local de las neoplasias de la tiroides por influencia de factores ambientales, implicó la necesidad de establecer la frecuencia y descripción epidemiológica de esta patología en la zona central de la República del Ecuador
Objetivo: describir las características epidemiológicas de las neoplasias de la tiroides en la zona central del Ecuador durante los años 2012-2016.
Materiales y métodos: los datos se obtuvieron de las historias clínicas de pacientes diagnosticados con cáncer de tiroides en el Hospital Oncológico Dr. Julio Enrique Paredes, en el lapso establecido, analizándose variables como sexo, distribución demográfica porcentual provincial y cantonal, así como, los diferentes subtipos histopatológicos, antecedentes familiares y personales.
Resultados: se estableció un incremento exponencial de la casuística sobre todo en el sexo femenino, constatándose que la incidencia de cáncer de tiroides en ambos sexos aumentó con la edad, siendo el grupo etario de mayor incidencia el de 40 a 49 años. El 14% de pacientes tuvo como antecedente patológico familiar el diagnóstico de cáncer de tiroides y otros trastornos tales como hipotiroidismo el 34%; bocio sin especificar funcionalidad el 21%. Se demostró una elevada incidencia de esta neoplasia en las provincias: Tungurahua, en el cantón Ambato, su capital con 76% y Cotopaxi en la ciudad de Latacunga su capital provincial con 65%, con prevalencia del carcinoma papilar diferenciado.
Conclusiones: se constató alta incidencia de cáncer tiroideo a expensas del subtipo papilar y en menor grado los tipos papilar variante folicular y folicular. Consideramos que, la alta incidencia se asocia a marcadores sociodemográficos con el mejoramiento en la atención de salud y su capacidad diagnóstica.
PERANCANGAN SISTEM INFORMASI PEMESANAN GAS LPJ BERBASIS ONLINE PADA PANGKALAN TETI TANJUNG MUTIARA KAB. AGAM
Authors: Arman Arman , Elizamiharti Elizamiharti , Nelfira Nelfira , Yovi Yanti Fauziah 
Published: July 2021

This research is motivated by the high interest and demand for LPG gas among the people in Tanjung Muatiara resulting in LPG gas often experiencing scarcity at several gas bases, all because the people only make reservations at bases in their home environment. To get information about LPG gas supplies, the public must visit bases to directly inquire of LPG gas supplies to the base owner. For this reason, through this research a website-based online design and application of LPG gas ordering information system was conducted. The system design in this application program uses the PHP programming language and MySQL database. The software development model used in this study is the waterfall SDLC model often also called sequential linear nods or classic life cycles. This study aims to build an information system that can provide information about LPG gas inventories at Teti Tanjung Mutiara Base and implement a website as a medium to promote and place online orders at Teti Tanjung Mutiara so as to facilitate the ordering process by customers.
The effect of electron beam on oxidative stress and inflammatory factors in diabetes mellitus: An in vitro and in vivo study
Authors: Martirosyan Danik , Shahnazari-Aval Masoomeh , Reza Ashoori Mohammad , Seyed Mikaeili Afsaneh , Nakhjavani Manouchehr , Mirmiranpour Hossein 
Published: July 2021

Background: The main purpose of this study was to investigate whether or not electron beam therapy (EBT) was an effective method in terms of moderating oxidative stress by reducing free radicals in BALB/c mice with type 1 diabetes mellitus.Methods: The study was performed on thirty BALB/c mice in three groups including normal control, diabetic control, and EBT treated. Before studying the effect of electron beam on the studied groups, optimal level of constant source-to-surface distance, as well as the effects of EBT on glutathione reductase (GR) structure and function were determined. After studying the structure and the function of GR protein with three methods including fluorometry, circular dichroism (CD), and activity assay methods, SSD 100 was selected for EBT. Glucose, advanced glycation end-products, GR, oxidative stress factors such as hydrogen peroxide, malondialdehyde, advanced oxidation protein products, oxidized low-density lipoprotein, and inflammatory factors were measured in the serum of all groups.Results: The results of in vitro study showed that electron beam therapy could increase glutathione reductase activity, which was not significant. Also, the results were compared between and within groups using one-way analysis of variance. Significant differences were observed for all variables measured between the normal control group and the other groups (P < 0.05). There was also no significant difference in blood glucose levels between the electron beam therapy treated group and the diabetic one (P > 0.05).Conclusion: The results suggested that electron beam therapy could be effective in reducing free radicals and oxidative stress. Electron beam therapy, as a complementary method, might aid in moderating the complications of diabetes mellitus.Keywords: Diabetes mellitus, Electron beam, Inflammatory factors, Oxidative stress
La importancia de la presencia de la familia en las instituciones que albergan a las personas mayores
Authors: Baró Silvana , Di Croce Pablo , Gómez González Romina , Nadal Zaida 
Published: July 2021

En situaciones como necesidades de vivienda o de cuidados respecto de su salud, el vínculo con la familia es fundamental para la salud integral y el bienestar psicológico. El objetivo de este artículo es visualizar la importancia del vínculo de la familia con el adulto mayor institucionalizado desde los trabajadores de los hogares y residencias. A partir de entrevistas a equipos interdisciplinarios que se desempeñan en las instituciones de adultos mayores se concluye que la falta de la familia en las instituciones, especialmente públicas, afecta la salud de los adultos mayores ya que se pierden las redes de apoyo social tan importantes en esta etapa de la vida.
STOCHASTIC TRANSMISSION DYNAMICS OF COVID-19 WITHIN A DENSITY DEPENDENT POPULATION
Authors: Kwaghkor Lubem M. , Onah Stephen E. , Basi Ibrahim G. , Danjuma Theophilus 
Published: July 2021

Coronavirus diseases (COVID-19) is a respiratory disease. Most infected people are known to develop mild to moderate symptoms and recover without requiring special treatment except for those who have underlying medical conditions and the elderly have a higher risk of developing severe disease. This research is aimed at studying the probable spread of the COVID-19 virus within a completely susceptible density-dependent population using a modified exponential distribution function. The modified exponential distribution function was extended to include the Basic Reproduction Number which was computed using the Nigerian COVID-19 index cases from 27th February to 18th April, 2020 to be. Various interesting results were obtained for the including the time period for the spread for different population sizes. The duration of the spread of the virus is from 4 to 7 hours with an average of 5.5 hours. This indicates that, for one infectious person with to enter a completely susceptible population of size , the virus can spread through the entire population in about hours if no control measures are in place.
FLORISTIC COMPOSITION AND DIVERSITY OF TREE SPECIES IN KUMO TOWN AND ITS ENVIRONS
Authors: Abdullahi Sadiq , Abba H. M. 
Published: July 2021

Study was conducted on Floristic Composition and Diversity of Tree Species in Kumo Town and its Environs. The aim was to investigate the Tree Species Structure, composition and diversity. Systematic random sampling method was used to sample the Tree species. The result showed that a total number of Twenty –Seven (27) species belonging to 8 genera and 12 families were identified. The family Leguminosae: Mimosoideae had the highest number of 4 species. The family Combretaceae, Moraceae, Caesalpinoidceae, and Palmae had 3 species each. The family Anacaediaceae, Myrtaceae, were represented by 2 species each. The remaining 5 families; Balanitaceae, Bombacaceae, Meliaceae, Rhamnaceae and Sterculiaceae were represented by 1 species each. The plant with the highest dominance was Adansonia digitata. The Shannon Weiner index was 2.45 and Simpson index was 0.48. This study therefore concluded that the species Azadirachta indica was the most abundant, with highest Relative Density, Relative Frequency, and Importance Value Index in the study area. This study recommended that the plants that had the lowest IVI such as Prosopis africana, Cassia sieberiana, need urgent conservation measures
The Regional Resuscitation Guidelines for Pulseless Electrical Activity in Emergency Medical Services in the United Kingdom: A Systematic Review
Authors: Coppola Alison , Smyth Michael , Black Sarah , Johnston Sasha , Endacott Ruth 
Published: July 2021

Background Pulseless electrical activity (PEA) is managed in accordance with international and national guidelines. These guidelines are not fully evidenced, resulting in emergency medical services in the United Kingdom amending guidelines to support paramedics when making resuscitation decisions. This review examined the local guidelines of services to identify the local clinical management of PEA, summarise the available evidence and prioritise future research. Methods The review was conducted according to the Joanna Briggs Institute systematic review of text and opinion. The review included locally amended guidelines and cited evidence sources for the management of PEA. A three-step search strategy was applied. Textual data was extracted to form conclusions which were categorised into similar meaning and developed into synthesised findings. Results Twenty-two documents met the inclusion criteria; Twenty-seven conclusions were extracted and analysed to generate 10 categories, forming three synthesised themes: the variability in the clinical management of PEA between ambulance services; the early identification of reversible causes and appropriate treatment options to increase survivability; and the consensus for further research. Conclusion This review identified variability in the clinical management of PEA; the autonomy of paramedics, which patients to transport to hospital and the factors applied to inform resuscitation decisions. A summary of the evidence in support of the local guidelines found that the early identification and treatment to reverse the cause of PEA was important to patient survival, however, this was acknowledged as complex and challenging to achieve. There was a consensus to improve patient outcomes using prognostic research.
Análisis de la calidad del servicio y la satisfacción del cliente en la práctica de rafting en el cantón Tena
Authors: Toalombo Díaz Álvaro Santiago , Cevallos Punguil Tania Cristina , Rivadeneyra Olalla Gary Patricio , Aguilar Soria Esteban Alejandro 
Published: July 2021

El rafting es una actividad que consiste en navegar ríos, controlada por el navegante empleando remos, con un equipamiento y personal capacitado para la guianza en el recorrido. El propósito de esta investigación es analizar la calidad del servicio y satisfacción del cliente en la práctica del rafting en el cantón Tena, año 2020. El diseño de la investigación fue cuantitativo y de tipo descriptivo, con el uso de métodos estadísticos de coeficiente correlacional y análisis de varianza ANOVA unifactorial. Se aplicó una encuesta de modelo SERVQUAL, a una muestra de 385 clientes de las Agencias de viaje del cantón Tena, Entre los resultados se evidencia que el índice de la calidad refleja a la tangibilidad como la dimensión con menor promedio de percepción, el cálculo del promedio general de las 5 dimensiones valoradas sobre un valor de 4.06 representa 81.44% de los clientes que perciben un buen servicio de calidad de acuerdo al grado de porcentaje 0-100% de la escala de Likert. Se concluyó que las brechas más altas con la percepción del cliente y su expectativa son tangibilidad (-0,06), fiabilidad (-0,06) y empatía (-0,05), puntos donde se necesita implementar estrategias de calidad, el análisis de las hipótesis, refleja un coeficiente de correlación sobre la calidad del servicio y la satisfacción del cliente con un 0,828 y una significativa de 0,01, el análisis de la correlación multivariente las dimensiones del calidad tales como tangibilidad y capacidad de respuesta, no se relacionan con la percepción del cliente frente al servicio.
La importancia de la información contable ante la incertidumbre del Covid-19, en las Mipymes en el entorno de los negocios en la región 6.
Authors: Becerra Molina Edison , Jaramillo Calle Yolanda , Astudillo Arias Pedro 
Published: July 2021

Introducción. La contabilidad es la ciencia que trata de las actividades económicas y financieras en forma cronológica y cuantificada para clasificarlas, registrarlas, resumirlas en estados financieros y luego analizarlas e interpretarlas. Objetivo. Formular una propuesta estratégica para el manejo eficaz de la información contable, ante la incertidumbre del COVID-19 en las Mipymes en el entorno de los negocios en la región 6. Metodología. El diseño de la investigación partió del paradigma de investigación positivista, tipo de investigación diseño de campo no experimental y transversal con apoyo documental, nivel de investigación descriptiva, la población fue de 77.289 y la muestra de 471, se utilizó la técnica de la encuesta, mediante el instrumento del cuestionario, constó con 8 items, fue validado mediante el juicio de tres expertos con experiencia en el área de contabilidad, emprendimiento y metodología, calificando claridad, coherencia, relevancia, puntaje, calificación e indicador. Resultados. Con respecto a la producción los encuestados sostuvieron en un 24,31%, que es importante que las empresas opten por diversificar sus productos, que es necesario revisar la rentabilidad, el 22,23%, para evaluar los posibles escenarios que pueden afectar a los negocios, falta de liquidez el 19,39%, ya que no cuentan con dinero suficiente para afrontar pasivos y gastos, la empresa debe cerrar sus puertas, el empleo está representada con un 19,02%, es importante recalcar que muchos de los negocios tuvieron que hacer recorte de personal y afectaron los ingresos de los empleados y del empleador, el 13,45% sostienen que existe un desfase presupuestario y que ocurrió un desequilibrio en sus planificaciones, y un 1,80% de los negocios deben ser responsables con la utilización del capital que deben manejar. Conclusión. Se concluyó que las diferentes acciones sin duda generaron un impacto económico tanto para la liquidez de las empresas como en quienes dependían de las mismas.
O laser no tratamento de lesão por pressão
Authors: Santos Jaqueline Mendes Gois , Silva Ana Cristina Rosa da , Amorim Cintia Ferreira de , Pereira Filho Edilson da Silva 
Published: July 2021

Objetivo: Descrever o uso do laser no tratamento de lesão por pressão mostrando seus benefícios, sua eficácia e menos tempos no reparo tecidual Método: Trata de uma revisão bibliográfica de caráter qualitativo sob revisão artigos que encontraram efeitos positivos da laserterapia a utilizando comprimentos de onda, utilizando as seguintes bases de dados para o levantamento de obras SCIELO, PubMed, os critérios de inclusão foram artigos publicados entre 2013 a 2018 em português e inglês, combinados através do operador booleano AND. Resultados e Discussão: Resulta quanto à eficácia da ação do laser como terapêutica principal na reepitelização do tecido lesionado, o sítio de aplicação do laser e lesões apresentadas pelos artigos em maior prevalência na região sacral. Além disso, o uso do laser pode ser recomendado na saúde pública e instituições privadas, possibilitando a diminuição de custos e independência aos profissionais. Conclusão: Deste modo, a laserterapia é um tratamento adjutório com ações capaz de contribuir em resolutividade acelerada, decorrente do processo de cicatrização de lesões tecidual, com evidencia na ação antiinflamatória, analgésico e cicatrizantes, onde constitui uma atuação dinâmica nos efeitos bioquímicos. Com resultados disso, o uso do laser vem trazendo um impacto positivo, proporcionando bem-estar e qualidade de vida aos clientes.
A Novel Plug-Based Vascular Closure Device for Percutaneous Femoral Artery Closure in Patients Undergoing Minimally-Invasive Valve Surgery
Authors: Schaefer Andreas , Sarwari Harun , Reichenspurner Hermann , Conradi Lenard 
Published: July 2021

Objectives: Surgical exposure of groin vessels to establish cardiopulmonary bypass (CPB) for minimally-invasive valve surgery (MIS) is standard of care but may result in postoperative wound healing disorders or seroma formation. Therefore, adaption of transcatheter techniques for fully percutaneous insertion of CPB cannulae may improve clinical results. We herein analyze a single center experience with a novel plug-based vascular closure device for MIS.Methods: Between 03/2020 and 02/2021 MIS using the MANTA™ (Teleflex Medical Inc., Wayne, PA, USA) vascular closure device was performed in 28 consecutive patients (58.8 ± 10.6 years, 60.3% male, logEuroSCORE II 1.1 ± 0.8%) receiving mitral and/or tricuspid valve repair/replacement. Concomitant procedures were left atrial appendage occlusion and cryoablation for atrial fibrillation in 21.4% (6/28) and 10.7% (3/28) of patients, respectively. Data were retrospectively analyzed in accordance with standardized M-VARC definitions. MANTA™ device success and early safety was defined as absence of any access site or access related vascular injury and major and life-threatening bleeding complications.Results: MANTA™ device success with immediate hemostasis and early safety were 96.4% (27/28). In one case, device failure necessitated surgical cut down without further complications. Mean aortic cross clamp time and cardiopulmonary bypass were 96.5 ± 24.2 min and 150.2 ± 33.6 min. Stroke, renal failure or myocardial infarction were not observed. Intensive care unit and total hospital stay were 1.7 ± 0.8 days and 10.1 ± 5.7 days. Overall 30-day mortality was 0%. Post-procedure echocardiography presented one case of residual moderate tricuspid regurgitation and competent valves in all other cases.Conclusions: The MANTA™ device is safe and effective in MIS. Its ease of use and effectiveness to achieve immediate hemostasis have further simplified MIS.