bluuebunny/crossref_metadata_2025_split huggingface dataset:
Call Characteristics of Patients Suspected of Transient Ischemic Attack (TIA) or Stroke During Out-of-Hours Service: A Comparison Between Men and Women
Authors: Exalto Lieza G. , van Doorn Sander , Erkelens D. Carmen A. , Smit Karin , Rutten Frans H. , Kappelle L. Jaap , Zwart Dorien L. M. 
Published: June 2021

Background: In the Netherlands, a digital decision support system for telephone triage at out-of-hours services in primary care (OHS-PC) is used. Differences in help-seeking behavior between men and women when transient ischemic attack (TIA) or stroke is suspected could potentially affect telephone triage and allocation of urgency.Aim: To assess patient and call characteristics and allocated urgencies between women and men who contacted OHS-PC with suspected TIA/stroke.Methods: A cross-sectional study of 1,266 telephone triage recordings of subjects with suspected neurological symptoms calling the OHS-PC between 2014 and 2016. The allocated urgencies were derived from the electronic medical records of the OHS-PC and the final diagnosis from the patient's own general practitioner, including diagnoses based on hospital specialist letters.Results: Five hundred forty-six men (mean age = 67.3 ± 17.1) and 720 women (mean age = 69.6 ± 19.5) were included. TIA/stroke was diagnosed in 294 men (54%) (mean age = 72.3 ± 13.6) and 366 women (51%) (mean age = 78.0 ± 13.8). In both genders, FAST (face-arm-speech test) symptoms were common in TIA/stroke (men 78%, women 82%) but also in no TIA/stroke (men 63%, women 62%). Men with TIA/stroke had shorter call durations than men without TIA/stroke (7.10 vs. 8.20 min, p = 0.001), whereas in women this difference was smaller and not significant (7.41 vs. 7.56 min, p = 0.41). Both genders were allocated high urgency in 75% of the final TIA/stroke cases.Conclusion: Overall, patient and call characteristics are mostly comparable between men and women, and these only modestly assist in identifying TIA/stroke. There were no gender differences in allocated urgencies after telephone triage in patients with TIA/stroke.
Weak Association Between the Glutamate Decarboxylase 1 Gene (GAD1) and Schizophrenia in Han Chinese Population
Authors: Zhang Luwen , Li Zhen , Liu Qing , Shao Minglong , Sun Fuping , Su Xi , Song Meng , Zhang Yan , Ding Minli , Lu Yanli , Liu Jiewei , Yang Yongfeng , Li Ming , Li Wenqiang , Lv Luxian 
Published: June 2021

ObjectivesSchizophrenia (SZ) is a complex psychiatric disorder with high heritability, and genetic components are thought to be pivotal risk factors for this illness. The glutamate decarboxylase 1 gene (GAD1) was hypothesized to be a candidate risk locus for SZ given its crucial role in the GABAergic neurotransmission system, and previous studies have examined the associations of single nucleotide polymorphisms (SNPs) spanning the GAD1 gene with SZ. However, inconsistent results were obtained. We hence examined the associations between GAD1 SNPs and SZ in two independent case-control samples of Han Chinese ancestry.Materials and MethodsTwo Han Chinese SZ case-control samples, referred as the discovery sample and the replication sample, respectively, were recruited for the current study. The discovery sample comprised of 528 paranoid SZ cases (with age of first onset ≥ 18) and 528 healthy controls; the independent replication sample contained 1,256 early onset SZ cases (with age of first onset &lt; 18) and 2,661 healthy controls. Logistic regression analysis was performed to examine the associations between GAD1 SNPs and SZ.ResultsTen SNPs covering GAD1 gene were analyzed in the discovery sample, and two SNPs showed nominal associations with SZ (rs2241165, P = 0.0181, OR = 1.261; rs2241164, P = 0.0225, OR = 1.219). SNP rs2241164 was also nominally significant in the independent replication sample (P = 0.0462, OR = 1.110), and the significance became stronger in a subsequent meta-analysis combining both discovery and replication samples (P = 0.00398, OR = 1.138). Nevertheless, such association could not survive multiple corrections, although the effect size of rs2241164 was comparable with other SZ risk loci identified in genome-wide association studies (GWAS) in Han Chinese population. We also examined the associations between GAD1 SNPs and SZ in published datasets of SZ GWAS in East Asians and Europeans, and no significant associations were observed.ConclusionWe observed weak associations between GAD1 SNPs and risk of SZ in Han Chinese populations. Further analyses in larger Han Chinese samples with more detailed phenotyping are necessary to elucidate the genetic correlation between GAD1 SNPs and SZ.
Fluorescein-Guided Panendoscopy for Head and Neck Cancer Using Handheld Probe-Based Confocal Laser Endomicroscopy: A Pilot Study
Authors: Dittberner Andreas , Ziadat Rafat , Hoffmann Franziska , Pertzborn David , Gassler Nikolaus , Guntinas-Lichius Orlando 
Published: June 2021

BackgroundWhite-light endoscopy and microscopy combined with histological analysis is currently the mainstay for intraprocedural tissue diagnosis during panendoscopy for head and neck cancer. However, taking biopsies leads to selection bias, ex vivo histopathology is time-consuming, and the advantages of in-vivo intraoperative decision making cannot be used. Confocal laser endomicroscopy (CLE) has the potential for a rapid and histological assessment in the head and neck operating room.MethodsBetween July 2019 and January 2020, 13 patients (69% male, median age: 61 years) with newly diagnosed head and neck cancer (T3/T4: 46%) underwent fluorescein-guided panendoscopy. CLE was performed from both the tumor and margins followed by biopsies from the CLE spots. The biopsies were processed for histopathology. The CLE images were ex vivo classified blinded with a CLE cancer score (DOC score). The classification was compared to the histopathological results.ResultsMedian additional time for CLE during surgery was 9 min. A total of 2,565 CLE images were taken (median CLE images: 178 per patient; 68 per biopsy; evaluable 87.5%). The concordance between histopathology and CLE images varied between the patients from 82.5 to 98.6%. The sensitivity, specificity, and accuracy to detect cancer using the classified CLE images was 87.5, 80.0, and 84.6%, respectively. The positive and negative predictive values were 87.0 and 80.0%, respectively.ConclusionCLE with a rigid handheld probe is easy and intuitive to handle during panendoscopy. As next step, the high accuracy of ex vivo CLE image classification for tumor tissue suggests the validation of CLE in vivo. This will evolve CLE as a complementary tool for in vivo intraoperative diagnosis during panendoscopy.
Perception of Healthcare Providers About the Use of Social Media to Manage a Healthy Diet in Saudi Arabia
Authors: Alanzi Turki , Altuwailib Maryam , Saadah Amjad Mohammed , Alanezi Fahad 
Published: June 2021

Purpose: The objective of this study is to investigate the perceptions of healthcare providers about the use of social media for healthy diet management in Saudi Arabia.Participants and Methods: A cross-sectional study was designed to investigate the use of social media healthy diet management. The sample constituted 308 healthcare professionals from Saudi Arabia. The social media application, WhatsApp is employed to distribute the questionnaire, which has achieved a response rate of 50.61%. Out of the total participants, 55% of the participants were under 30 years of age, 71% were females, and 55% of the participants had a bachelor's degree.Results: Among the total respondents, 66% used social networking applications more than four hours a day, and 78% utilized social media to get information about a healthy diet. The respondents employed the following platforms for this purpose: Instagram (27%), YouTube (19%), Snapchat (19%), WhatsApp (18%), Twitter (8%), and Facebook (5%). The respondents considered that social media is very helpful to educate (44%), communicate with specialists (33%), and get applications for a healthy diet (38%). They held an opinion that social media is very helpful in improving knowledge about a healthy diet (47%), creating diet awareness (42%), and achieving healthy diet outcomes (37%) and lifestyle (37%).Conclusion: According to the perception of health providers, social media can be used to promote healthy diet management in Saudi Arabia. Also, the growing use of social media in Saudi Arabia represents the potential to create programs that encourage and promote healthy eating habits in the Kingdom of Saudi Arabia. Instagram, YouTube, Snapchat, and WhatsApp platforms can be used for this purpose.
An Initial 5-Year Single-Center Experience of 365 Patients Undergoing the Video-Assisted Thoracoscopic Surgery for Nuss Procedure for Pectus Excavatum in Resource-Scare Setting
Authors: Nguyen The-May , Le Van-Thieu , Nguyen Huu-Uoc , Pham Huu-Lu , Phung Hong-Son Duy , Vu Ngoc-Tu , Nguyen Viet-Anh , Do Nam-Khanh , Vu Kim-Duy , Vo Hoang-Long , Doan Quoc-Hung 
Published: June 2021

Background: Little is known about video-assisted thoracoscopic surgery in the Nuss procedure (VATS-NUSS) and its postoperative outcomes in the resource-scarce conditions in clinical practice such as Vietnam. Available evidence in the literature was mostly reported from large institutions in developed countries. Hence, this study was conducted to review our initial large single-center experience in the use of the VATS-NUSS for patients with pectus excavatum (PE) within 5 years.Methods: Data from 365 consecutive PE patients between January 2015 and December 2019 who were surgically treated with VATS-NUSS were retrospectively analyzed.Results: Of 365 patients, median age at operation was 15.61 ± 3.73 years (range = 5–27 years), most being child and adolescent. Three hundred nine patients (84.65%) were male. PE was commonly detected at puberty (n = 328, 89.9%). Postoperatively, early complications consisted of pneumothorax (n = 5, 1.37%), pleural bleeding/pleural fluid (n = 2, 0.55%), pleural hematoma (n = 1, 0.27%), pneumonia (n = 1, 0.27%), surgical wound infection (n = 1, 0.27%), incision fluid accumulation (n = 3, 0.82%), metal bar infection (n = 1, 0.27%), atelectasis (n = 3, 0.82%), and fever (n = 8, 2.19%). Late complications included surgical wound infection (n = 2, 0.55%), metal bar deviation (n = 5, 1.37%), metal bar allergy (n = 10, 2.74%), recurrent PE (n = 2, 0.55%), and persistent PE (n = 5, 1.37%). No deaths occurred. In 175 patients (47.95%) experiencing bar removal, mean operative time for bar removal was 34.09 ± 10.61 min, and the length of hospitalization following bar removal was 2.4 ± 1.34 days; the most frequent complication was pneumothorax (n = 19, 10.85%). One wound infection and one incision fluid accumulation happened following bar removal. Favorable midterm to long-term postoperative outcomes were achieved.Conclusions: From the beginning of the Vietnamese surgeons' experience, VATS-NUSS application obtained favorable outcomes with minimizing the occurrence of serious intraoperative and postoperative complications. Current rare evidence enables to give a real picture in the application, modification, and development of VATS-NUSS in the countries having similar resource-scarce conditions.
ACTIVE OPERATIONS OF COMMERCIAL BANKS IN RUSSIA: TRANSFORMATIONS AND DEVELOPMENT PROSPECTS
Authors: Цакаев А.Х. , Мальсагова Х.Р. 
Published: June 2021

Рассмотрены теоретические аспекты осуществления коммерческими банками активных операций, включая их экономическую сущность и их дифференциацию в зависимости от доходности, ликвидности и рискованности. Последняя рассматривается как потенциальная вероятность потерь при превращении активов в денежные средства. Раскрыты специфические проблемы осуществления активных операций коммерческими банками с государственным участие, частными коммерческими банками, коммерческими банками с иностранным капиталом и коммерческими банками с российским капиталом. Представлены результаты анализа структуры активных операций ПАО Альфабанк , ПАО Сбербанк России и ПАО МИнбанк в 90е, 2000е и последнего десятилетия. Сформулированы выводы и рекомендации совершенствования сферы активных операций коммерческих банков в России к условиям санкционного режима.
The theoretical aspects of the implementation of active operations by commercial banks, including their economic nature and their differentiation depending on profitability, liquidity and risk are Considered. The latter is considered as a potential probability of losses in the conversion of assets into cash. The specific problems of active operations by commercial banks with state participation, private commercial banks, commercial banks with foreign capital and commercial banks with Russian capital are revealed. The results of the analysis of the structure of active operations of PJSC Sberbank of Russia, PJSC AlfaBank and PJSC Finbank in the 90s, 2000s and last decade are presented. Conclusions and recommendations for improving the scope of active operations of commercial banks in Russia to the conditions of the sanctions regime are formulated.
BASIC ASPECTS AND PRINCIPLES OF USING MULTIMEDIA TECHNOLOGIES IN INCLUSIVE EDUCATION
Authors: Алисултанова Э.Д. , Бисултанова А.А. 
Published: June 2021

В статье рассматривается вопрос включения лиц с инвалидностью и ограниченными возможностями здоровья в общество с помощью мультимедиа технологии. Представлен макет системы. Инклюзивное образование может заложить основы более инклюзивного общества, в котором все люди равны и где иное воспринимается и ценится как часть человечества. Школьное инклюзивное образование дает возможность учащимся, не являющимся инвалидами, делиться со сверстниками, которые отличаются от них, так научиться принимать и уважать эти различия . В свою очередь, ученикиинвалиды имеют возможность стать частью школьного сообщества и получить реалистичное представление о том, как выглядит конкурентоспособное общество, а также о своих собственных возможностях и ограничениях. Они уполномочены более полно участвовать в жизни общества. В настоящее время инклюзивное образование является фундаментальным правом, вытекающим из принципа справедливости. В этом контексте необходима согласованная политика и практика в области образования для удовлетворения разнообразных потребностей учащихся и обеспечения того, чтобы все учащиеся, включая инвалидов, имели равные возможности в образовании. Достигается это путем диверсификации практики образования.
The article discusses the inclusion of persons with disabilities and disabilities in society using multimedia technology. The layout of the system is presented. Inclusive education can lay the foundations of a more inclusive society in which all people are equal and where the other is perceived and valued as part of humanity. Inclusive school education enables students who are not disabled to share with peers who are different from them, so learn to accept and respect these differences. In turn, students with disabilities have the opportunity to become part of the school community and get a realistic idea of what a competitive society looks like, as well as their own opportunities and limitations. They are authorized to participate more fully in society. At present, inclusive education is a fundamental right arising from the principle of justice. In this context, coherent education policies and practices are needed to meet the diverse needs of students and to ensure that all students, including persons with disabilities, have equal educational opportunities. This is achieved through the diversification of educational practices.
FINDING TRANSFORMATION MATRIXS FOR A GIVEN MATRIX BY THE METHOD OF LINEAR ALGEBRA AND SOLVING THE PROBLEM WITH THE HELP OF MATHCAD
Authors: Хадисов М-Р. Б. , Саидов А-В. А. 
Published: June 2021

В статье рассмотрены вопросы нахождения перестановочных матриц для заданной матрицы методом линейной алгебры и решение задачи с помощью программы МATHCAD.
The article considers the issues of finding permutation matrices for a given matrix by the method of linear algebra and solving the problem using the МATHCADs program.
ANALYSIS OF THE TECHNOLOGY “INTERNET OF THINGS” (IOT) AND ITS ROLE IN THE “SMART HOUSE” PROJECT
Authors: Мальцагов Х.Х. , Хаджиева Л.К. 
Published: June 2021

В данной публикации рассмотрена технология интернет вещей и ее роль в проекте Умный дом и в системе безопасности, которую они могут предоставить, а также о ее актуальности в современном мире. Количество и качество возможностей умного дома зависит только от желания и финансовых возможностей владельца. Кто-то может устанавливать всевозможные датчики температуры, газа, движения, автоматическое освещение и шторы, кто-то может ограничиться умным чайником. Самая важная и актуальная для человека функция умного дома это безопасность, которую он может обеспечить, для этого могут, например, использоваться электронные замки, которые открываются со смартфона владельца или по паролю, камеры видеонаблюдения, датчики движения. Все это возможно благодаря технологии интернет вещей, которая связывает все устройства в доме в единую сеть.
This publication discusses the technology of the Internet of things and its role in the Smart Home project, and in the security system that they can provide, as well as its relevance in the modern world. The quantity and quality of the capabilities of a smart home depends only on the desire and financial capabilities of the owner. Someone can install all kinds of sensors for temperature, gas, movement, automatic lighting and curtains, someone can be limited to a smart kettle. The most important and relevant function of a smart home for a person is the security that it can provide, for this, for example, electronic locks can be used that open from the owners smartphone or password, video surveillance cameras, motion sensors. All this is possible thanks to the Internet of Things technology, which connects all the devices in the house into a single network.
Studi Deskriptif Tingkat Pengetahuan Akseptor KB Tentang Alat Kontrasepsi Pil Kombinasi
Authors: Yuhemy Zurizah  
Published: June 2021

Laju pertumbuhan penduduk (LPP) Indonesia memiliki kecenderungan menurun. Kebijakan pemerintah untuk menekan LPP dengan adanya program Keluarga Berencana (KB) yang diluncurkan pada tahun 1980an semakin nyata hasilnya. Pada tahun 1971-1980 pertumbuhan penduduk Indonesia masih cukup tinggi sekitar 2,33 persen. Pertumbuhan penduduk ini kemudian mengalami penurunan yang cukup tajam hingga mencapai 1,44 persen pada 1990-2000. Penurunan ini antara lain disebabkan berkurangnya tingkat kelahiran sebagai dampak peran serta masyarakat dalam program KB. Namun pada periode sepuluh tahun berikutnya, tepatnya awal masa reformasi tahun 2000-2010 laju pertumbuhan ini mengalami sedikit peningkatan sekitar 0,05 persen. Laju pertumbuhan penduduk apabila tidak dikendalikan berakibat pada meningkatnya jumlah penduduk.Penelitian ini ingin mengungkapkan bagaimana gambaran tingkat pengetahuan Akseptor KB tentang Pil Kombinasi di Desa Mainan kecamatan Sembawa Kabupaten Banyuasin. Penelitian ini bertujuan untuk mengetahui gambaran tingkat pengetahuan akseptor KB tentang Alat kontrasepsi Pil kombinasi Desain penelitian ini menggunakan studi deskriptif. Tehnik pengambilan sampling dengan non probability sampling yaitu porposive sampling sedangkan tehnik analisanya adalah univariate yang dilakukan terhadap tiap variable dari hasil penelitian. Sample yang digunakan adalah 44 responden. Data yang dikumpulkan berasal dari data primer dan data sekunder dengan menggunakan kuesioner. Dari hasil penelitian didapatkan hasil mayoritas responden memiliki tingkat pengetahuan yang kurang sebanyak 22 ( 50 % ) responden,tingkat pengetahuan cukup sebanyak 12 ( 27,27 % ) responden dan tingkat pengetahuan baik sebanyak 10 ( 22,72 % ). Akhir dari kesimpulannya adalah tingkat pengetahuan responden yang kurang, kemudian dapat disarankan kepada petugas kesehatan untuk lebih meningkatkan kualitas pelayanan KB dengan konseling Pil Kombinasi.
PENERAPAN KLAUSULA BAKU PADA PERJANJIAN GADAI PADA PT. PEGADAIAN (PERSERO)
Authors: Djaman Sartika Anggriani 
Published: June 2021

Tujuan dilakukannya penelitian ini adalah untuk mengetahui tentang penerapan klausula baku dalam perjanjian gadai dan hak dan kewajiban kreditur dan debitur. Dengan metode penelitian hukum normatif disimpulkan bahwa: 1. Pembuatan klausula baku pada perjanjian gadai pada PT Pegadaian kurang melindungi kepentingan hukum nasabah. Hal ini disebabkan karena isi perjanjian memuat syarat perjanjian, asas kebebasan berkontrak, serta hak dan kewajiban para pihak yang tidak proporsional, sehingga secara yuridis normatif menyimpang dari prinsip-prinsip umum perjanjian yang seharusnya berlaku. 2. PT Pegadaian sepenuhnya bertanggung jawab jika terjadi wanprestasi dan terdapat kesalahan yang terkait dengan kerusakan atau kerugian nasabah yang disebabkan kekalaian pihak Pegadaian, sedangkan bila terjadi kesalahan menaksir dan lelang barang gadai (tanpa diketahui pemiliknya) kurang bertanggung jawab. Hal tersebut terjadi karena tidak ada atau belum adanya komplain dari nasabah. Sedangkan pihak debitur/nasabah melakukan wanprestasinya dalam bentuk tidak membayar pinjaman setelah jatuh tempo, maka sudah selayaknya untuk menerima semua konsekuensi perjanjian yang lebih banyak dalam bentuk risiko lelang barang gadai. Kata kunci: perjanjian baku, gadai
PENERAPAN PRUDENTIAL BANKING PRINCIPLE DALAM UPAYA PERLINDUNGAN HUKUM BAGI NASABAH PENYIMPAN DANA
Authors: Dendhana Toto 
Published: June 2021

Tujuan penelitian ini adalah untuk mengetahui bagaimanakah penerapan prinsip kehati-hatian pada kegiatan operasional bank, bagaimanakah implementasi prinsip kehati-hatian bank yang diatur oleh Undang-undang Perbankan, dan manfaat apakah yang dapat diperoleh dalam penerapan prinsip kehati-hatian dalam kegiatan operasional bank. Dengan menggunakan penelitian hukum normatif disimpulkan bahwa: 1. Bank dalam kegiatan operasional perbankannya harus menerapkan prinsip kehati-hatian (prudential banking) dimana prinsip kehati-hatian dalam mengelola dan menjalankan aktivitas perbankan sehari-hari, bertujuan untuk menjaga kesehatan bank. 2. Implementasi prinsip kehati-hatian yang diatur melalui UU Perbankan keberadaannya dalam UU No. 7/1992 dan perubahannya yaitu UU No.10/1998 tentang Perbankan, telah diatur secara tegas. 3. Manfaat dengan diterapkannya prinsip kehati-hatian bank, yaitu: (1) Bagi bank pelaksana, dalam melakukan usahanya akan melindungi kepentingan nasabah penyimpan dana khususnya, dapat memberikan pelayanan jasa perbankan yang cepat, murah dan aman sehingga akan meningkatkan kepercayaan masyarakat terhadap bank tersebut sebagai bank yang benar-benar prudent dan solid; (2) Manfaat bagi nasabah, yaitu nasabah dapat memperoleh pelayanan jasa perbankan yang aman, cepat dan menguntungkan bagi transaksinya disamping nasabah akan terbebas dari perasaan was-was, akan nasib simpanannya akibat ditutupnya bank; (3) Manfaat bagi pemerintah; untuk stabilitas moneter. Kata kunci: prudential banking principle, nasabah