bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Continuous Subcutaneous Insulin Infusion and Multiple Daily Injections in Pediatric Type 1 Diabetes: A Meta‐Analysis and Prospective Cohort Study
Authors: Wang Xu , Zhao Xue , Chen Danrong , Zhang Mingzhi , Gu Wei 
Published: March 2021

BackgroundThe incidence of pediatric type 1 diabetes (T1D) is increasing worldwide, and the appropriate choice of therapy regimens is important for children, especially in developing countries with inadequate resources.MethodsWe conducted a design combining meta-analysis and prospective cohort study. In meta-analysis, 14 studies involving 69,085 TID cases reported glycosylated hemoglobin (HbA1c) levels, including 48,363 multiple daily insulin injections therapy (MIT) and 20,722 continuous subcutaneous insulin infusion (CSII). In our prospective cohort study, TID cases were recruited from a tertiary children’s hospital, and randomly divided into Group MIT and Group CSII. After the 4-year follow-up, the effects of MDI (n = 112) and CSII (n = 76) therapy on glycemic control, long-term complications, as well as the growth and pubertal development were explored.ResultsCompared to CSII in TID, HbA1c levels in MDI (WMD = 0.21, 95% CI: 0.20 to 0.23) were increased significantly in meta-analysis. Among 188 clinical cases, mean age at recruitment was 7.55 (SD 2.91) years. Duration of TID was 4.23 (SD 2.61) years. 50.53% (n = 95) of them were boys. The 4-year follow-up showed that children’s HbA1c was 0.67 (95% CI −1.28, −0.05) % lower in children with CSII compared to children with MDI in multivariable regression models with adjustment for potential confounders (children’s age at follow-up, duration of TID, gender, birthweight, parity, and delivery method). CSII was associated with 2.31 kg higher in children’s weight (95% CI 0.59, 4.04) in the adjusted model. No difference was found in peripheral nerve and fundus consequences as well as the status of obesity and thin and pubertal development between CSII and MIT.ConclusionCSII might be associated with better glycemic control and better effect for children growth development. No higher risks of long-term complications and delayed pubertal development were observed in CSII. Our findings provided evidence for a better therapy regimen for T1D in children, nevertheless, they need to be validated by a larger sample size study.
Endovascular Management of Intracranial Atherosclerosis-Related Large Vessel Occlusion With the A Direct Aspiration First-Pass Thrombectomy Compared With Solumbra Technique
Authors: Li Zhao-Shuo , Zhou Teng-Fei , Li Qiang , Guan Min , Liu Huan , Zhu Liang-Fu , Wang Zi-Liang , Li Tian-Xiao , Gao Bu-Lang 
Published: March 2021

Background: To investigate the effect of the A Direct Aspiration First-Pass Thrombectomy (ADAPT) vs. Solumbra technique in the treatment of acute intracranial atherosclerosis-related large vessel occlusion (LVO).Methods: Patients with acute atherosclerosis-related LVO who had undergone endovascular treatment were retrospectively enrolled into two groups: The Solumbra and ADAPT groups. The clinical data were analyzed.Results: Patients (104) were enrolled with 48 in the Solumbra and 56 in the ADAPT group. The mean time from femoral access to recanalization was significantly (P &lt; 0.05) shorter in the ADAPT than in the Solumbra group. The recanalization time at the first line was significantly shorter in the ADAPT group than in the Solumbra group (17 ± 10.21 vs. 26 ± 15.55 min, P = 0.02). However, the rate of switching to the alternative was significantly higher in the ADAPT group than that in the Solumbra group (46.42 vs. 33.33%, P = 0.01). Eighty-two patients had eventual recanalization, resulting in a final recanalization rate of 78.85%. At 3-month clinical follow-up for all patients, the good prognosis rate reached 51.92% with good prognosis in 24 patients (50%) in the Solumbra and 30 (53.57%) in the ADAPT group. The rate of symptomatic intracranial hemorrhage was 18.75% (n = 9) in the Solumbra and 19.64% (n = 11) in the ADAPT group. The mortality rate was 21.15% (22/104). Among 80 (76.92%) patients who had angiographic follow-up (3–30 months), five (6.25%) patients experienced in-stent stenosis, and two (2.5%) experienced asymptomatic stent occlusion.Conclusion: In patients with acute intracranial atherosclerosis-related LVO, clinical outcomes treated using the ADAPT technique are comparable with those using the Solumbra technique, and more patients need additional remedial measures if treated with the ADAPT technique.
Combined Ultrasound and CT-Guided Iodine-125 Seeds Implantation for Treatment of Residual Hepatocellular Carcinoma Located at Complex Sites After Transcatheter Arterial Chemoembolization
Authors: Ren Yanqiao , Dong Xiangjun , Chen Lei , Sun Tao , Alwalid Osamah , Kan Xuefeng , Su Yangbo , Xiong Bin , Liang Huimin , Zheng Chuansheng , Han Ping 
Published: March 2021

PurposeThe purpose of this study was to evaluate the efficacy and safety of iodine-125 (125I) seeds implantation under ultrasound and computed tomography (CT) guidance in the treatment of residual hepatocellular carcinoma (HCC) located at complex sites after transcatheter arterial chemoembolization (TACE).MethodsThis retrospective study analyzed the consecutive medical records of 31 HCC patients with residual tumors located at complex sites (such as large blood vessels, gallbladder, diaphragm dome, etc.) after TACE from May 2014 to December 2018, all of whom received 125I seeds implantation therapy. Overall survival (OS), progression-free survival (PFS), recurrence, and complications were documented.ResultsA total of 607 seeds were implanted in 31 patients, with an average of 19.6±10.4 (range, 8–48) seeds per patient. Median OS and PFS were 33 months (95% CI: 27.1 months, 38.9 months) and 15 months (95% CI: 9.6 months, 20.4 months), respectively. Although univariate analysis showed that albumin, prothrombin time, alpha-fetoprotein level, Child-Pugh score, and lipiodol deposition in tumor were associated with OS, multivariate analysis showed that none of them was an independent prognostic factor for OS. Multivariate analysis showed that prothrombin time was an independent prognostic factor for PFS. No operation-related deaths in this study. Although pneumothorax was present in two patients and subcutaneous abscess in one patient, symptoms improved in all three patients with appropriate treatment. Common minor complications included fever, abdominal pain and leukopenia and no grade≥3 adverse events were observed.Conclusions125I seeds implantation under the combined guidance of ultrasound and CT is safe and effective for patients with residual HCC located at complex sites after TACE. This is a promising treatment approach and deserves further discussion.
Sleep Disturbances and Patterns in Children With Neurodevelopmental Conditions
Authors: Halstead Elizabeth J. , Joyce Anna , Sullivan Emma , Tywyn Carwyn , Davies Kyle , Jones Alexandra , Dimitriou Dagmara 
Published: March 2021

Background: Children with neurodevelopmental conditions (NDC) often experience sleep problems which are long-lasting and more complex than typically developing children. These sleep problems impact their families and there is little guidance for management specifically for sleep for families of children with neurodevelopmental conditions. The present study aims to use parental report to evaluate sleep disturbances and sleep patterns in a large sample of children with NDC. We aim to identify associations with age, diagnosis, and medication groups.Methods: Data on 601 children aged between 2 and 17 years was analyzed from a UK non-profit service for sleep for families of children with NDC. Parents/carers completed the children's sleep habit questionnaire, a 7 day sleep diary, and information on child age, diagnosis, and medication. Parents also reported previous sleep management techniques they had tried.Results: Overall, we found differences between age, diagnosis, and medication use groups for sleep disturbances and sleep diary parameters in these populations. Sensory conditions were associated with high night time waking duration. Parents reported their child's short sleep duration was the most common problem for them.Conclusions: Key areas for further research are outlined including the long term considerations for parental presence at bedtime for sleep anxiety, melatonin use and efficacy, and consideration for interventions to reduce daytime fatigue in children aged 7–11 years old.
Polymorphisms in the HTR2A and HTR3A Genes Contribute to Pain in TMD Myalgia
Authors: Louca Jounger Sofia , Christidis Nikolaos , Hedenberg-Magnusson Britt , List Thomas , Svensson Peter , Schalling Martin , Ernberg Malin 
Published: March 2021

Background: The aim of this study was to investigate if single nucleotide polymorphisms (SNPs) related to monoaminergic neurotransmission, in particular the serotonergic pathway, contribute to pain perception in patients with temporomandibular disorder (TMD) myalgia and if there is a correlation to jaw function as well as psychosocial factors such as stress, anxiety and depression.Materials and Methods: One hundred and seventeen individuals with TMD myalgia were included. A venous blood or saliva sample was taken for genetic analyses and genotyped regarding HTR2A (rs9316233) HTR3A (rs1062613), HTR3B (rs1176744), SERT (5-HTTLPR) and COMT (rs4680). A clinical examination according to Diagnostic Criteria for TMD (DC/TMD) was performed and axis II data (psychosocial factors) were compared between participants with different genotypes for each gene using Kruskall–Wallis test. The characteristic pain intensity (CPI) was tested for correlations to scores for the Perceived Stress Scale, Generalized Anxiety Disorder, and Patient Health Questionnaires using Spearman's rank correlation test with Bonferroni correction for multiple testing. To further explore data factor analysis was performed to identify latent factors associated to the outcome variables.Results: Participants carrying at least one copy of the rare allele of the HTR2A (rs9316233) and HTR3A (rs1062613) had higher CPI compared with the participants with the homozygous common genotype (P = 0.042 and P = 0.024, respectively). Correlation analyses showed several significant positive correlations between CPI on one hand, and self-reported psychosocial distress and jaw function on the other hand for several genotypes that mostly were weak to moderate. The factor analysis identified two latent variables. One was positively correlated to the HTR3B gene, jaw function and self-reported parafunctions, and the other was positively correlated to psychological distress and negatively correlated to SERT.Conclusion: Taken together, the polymorphism rs1062613 in the HTR3A gene contributes to pain intensity in TMD myalgia. This together with positive interactions between pain variables and psychological factors in genotypes strengthens that pain and psychological distress are related. Further research is needed to explore this as well as the influence of gene-to-gene interactions on pain and psychological distress.
Les buzzwords d’origine anglaise dans la langue française : simples anglicismes ou véritables néologismes ?
Authors: Jeandidier Aliénor 
Published: March 2021

Depuis la seconde moitié du XXe siècle, la mondialisation, l’expansion des médias et le développement des nouvelles technologies ont contribué à ériger l’anglais en langue internationale. Aussi est-il fréquent de rencontrer des anglicismes en français. Ces anglicismes pourraient être considérés comme des néologismes, n’étant pas issus de la langue française. Les buzzwords d’origine anglaise feraient partie de ces néologismes d’importation étrangère. Ces mots et expressions concourent à la création d’un phénomène de communication – le buzz – autour d’une idée perçue comme inédite. Ils tendent ensuite à disparaître ou à se banaliser, comme le ferait tout effet de mode. Les buzzwords d’origine anglaise sont cependant difficiles à cerner : sont-ils de simples anglicismes, ou comportent-ils des caractéristiques qui leur sont propres ? Comment, en outre, saisir l’essence du buzzword dont la vocation, semble-t-il, n’est pas de durer ?Cette étude se veut indicative d’un phénomène de communication relativement récent et contemporain. Elle examine différents types de buzzwords d’origine anglaise dans la langue française et tente de dégager leurs caractéristiques linguistiques. Notre contribution s’appuie sur une base de données constituée à partir d’échantillons récoltés dans les médias français et dans notre quotidien. Nous tâcherons en conséquence de définir les relations entre buzzwords d’origine anglaise, anglicismes et néologismes. Nous espérons ainsi montrer l’intérêt que ces buzzwords représentent en matière de néologie.
“How to be happy” according to Cosmopolitan: The metaphors of happiness at the service of positive psychology and neoliberalism ideology
Authors: Gomez Vicente Lucia 
Published: March 2021

The metaphorical representation of happiness in the women’s magazine industry appears to be of particular interest at the moment. Indeed, different political, social and economic actors have made happiness become one of the main objectives of Western societies, both at the individual (self-fulfillment, satisfaction, happiness) and at the collective (workplace wellness, well-being of society) level. However, beneath these laudable ideals, and despite their altruistic, apolitical and ideology-free appearance, there lies a discourse that pursues very clear objectives of benefit only to certain interest groups [Illouz & Cabanas 2018]. The women’s press represents a privileged source in the understanding of the expectations faced by women [Blandin 2018] and, perhaps in a more general way, by individuals in a particular culture. Finally, the metaphors used enable us to analyze certain thought patterns specific to some discourses [Charteris-Black 2004]. The aim of this paper is thus to understand how happiness is represented metaphorically in Cosmopolitan magazine and to determine whether this representation corresponds to an ideological agenda. A corpus-based analysis of the metaphors of happiness used in the Cosmopolitan magazine has been conducted. The results show that most of these metaphors can be categorized according to six conceptual patterns related to the notions of ‘strength’ and ‘limit’. The metaphors of happiness found in this corpus are shown to be ideologically charged and strongly related to positive psychology and neoliberal ideology.
Bayesian estimation of equivalent circuit parameters of photovoltaic cells
Authors: Tada Kazuya 
Published: March 2021

Abstract
The equivalent circuit model of a photovoltaic cell is useful for understanding device loss mechanisms as well as the design and analysis of systems using photovoltaic cells. Although nonlinear least-squares methods are routinely applied for the extraction of equivalent circuit parameters using current–voltage characteristic curves, they only yield a point estimation sensitive to the initial value and do not provide an estimation error. In this study, a data-driven approach using Bayesian estimation is proposed to extract equivalent circuit parameters. Contrary to the conventional least-squares method, this method does not require tedious initial value adjustments and provides an estimation error.
El tránsito de la literatura al cómic: "Ajuar funerario", de Fernando Iwasaki
Authors: Pina Arrabal Álvaro 
Published: March 2021

En este artículo se examina el cambio que los textos literarios y, en particular, los microcuentos experimentan al ser trasvasados al cómic. Para ello, se efectúa una comparativa entre los microrrelatos de Ajuar funerario (2004), de Fernando Iwasaki, y la adaptación homónima (2018) realizada por Imanol Ortiz y Beñat Olea. En primer lugar, se ofrecen algunos apuntes sobre la adaptación desde un punto de vista tanto cultural, a fin de entenderla como parte de un sistema social y económico que la configura, como formal, con la intención de sugerir algunas características que puedan ser comunes en un microrrelato y en su respectiva adaptación al cómic. A continuación, se plantean cinco bloques principales: “el cambio de página como unidad significativa”, “la concreción de la temporalidad en la imagen”, “desambiguación”, “metáfora” y “ausencia de texto y tipografía significativa”. Con todo ello se pretende valorar hasta qué punto se da una ganancia o una pérdida –si las hay– de las propiedades originales del microrrelato al ser vertido en un medio semiótico donde lo visual tiene una alta carga de significación. Se espera, en definitiva, aportar un estudio de caso a un terreno aún poco explorado: las adaptaciones de microrrelatos a cómics.
GLEAM: Galaxy Line Emission & Absorption Modeling
Authors: Stroe Andra , Savu Victor-Nicolae 
Published: March 2021

Abstract
We present Galaxy Line Emission & Absorption Modeling (gleam), a Python tool for fitting Gaussian models to emission and absorption lines in large samples of 1D extragalactic spectra. gleam is tailored to work well in batch mode without much human interaction. With gleam, users can uniformly process a variety of spectra, including galaxies and active galactic nuclei, in a wide range of instrument setups and signal-to-noise regimes. gleam also takes advantage of multiprocessing capabilities to process spectra in parallel. With the goal of enabling reproducible workflows for its users, gleam employs a small number of input files, including a central, user-friendly configuration in which fitting constraints can be defined for groups of spectra and overrides can be specified for edge cases. For each spectrum, gleam produces a table containing measurements and error bars for the detected spectral lines and continuum and upper limits for nondetections. For visual inspection and publishing, gleam can also produce plots of the data with fitted lines overlaid. In the present paper, we describe gleam’s main features, the necessary inputs, expected outputs, and some example applications, including thorough tests on a large sample of optical/infrared multi-object spectroscopic observations and integral field spectroscopic data. gleam is developed as an open-source project hosted at https://github.com/multiwavelength/gleam and welcomes community contributions.
Preceptor Perceptions of the Immersive Clinical Experience in Athletic Training Education
Authors: Eldred Cameron M. , Neil Elizabeth R. , Dougal Zachary J. , Walker Stacy E. , Grimes Anna Marie , Eberman Lindsey E. 
Published: March 2021

Context
Clinical immersion is a newly required concept within athletic training education, and preceptors play a critical role in facilitating athletic training students' learning during those experiences.

Objective
To explore the perceptions of preceptors currently supervising athletic training students who participate in immersive clinical experiences.

Design
Qualitative study.

Setting
Individual phone interview.

Patients or Other Participants
Preceptors from various clinical sites (4 females [40%] and 6 males [60%]) with an average age of 41 ± 18 years. Participants also had an average 7 ± 8 years of experience as a preceptor.

Data Collection and Analysis
Interviews occurred via individual phone interviews using a semistructured interview script. All interviews were audio-recorded and transcribed verbatim. A 3-person research team analyzed the data and coded it into domains and categories based on a consensus process. Credibility was established with multiple researchers, an external auditor, and member checks.

Results
Three domains emerged from the data: (1) exposure, (2) benefits, and (3) insufficient training. Participants stated that as a result of exposure the athletic training students experienced increased responsibility and trust, increased realistic work environment, increased collaborative practice experiences, and skill use and refinement. Preceptors indicated that the added benefits of immersive clinical experiences led to confidence in clinical and professional interactions. Preceptors noted insufficiency in their training, specific to the expectations of an immersive clinical experience. Many preceptors sought out independent learning opportunities to enhance their role as preceptor. There was a misunderstanding as to what the main differences were between traditional and immersive clinical experiences, as well as a lack of communicated or standardized goals and objectives.

Conclusions
Participants indicated that the immersive clinical experiences were beneficial for the athletic training students' professional development. The insufficiency of training and misunderstanding of the immersive clinical experience are concerning and could be enhanced with clearly set goals and objectives.
The Feasibility of Blinding Residency Programs to USMLE Step 1 Scores During GME Application, Interview, and Match Processes
Authors: Smith Kathy W. , Amini Richard , Banerjee Madhulika , Clemens Conrad J. 
Published: March 2021

ABSTRACT

Background
With the recent announcement that Step 1 score reporting will soon change to pass/fail, residency programs will need to reconsider their recruitment processes.

Objective
We (1) evaluated the feasibility of blinding residency programs to applicants' Step 1 scores and their number of attempts throughout the recruitment process; (2) described the selection process that resulted from the blinding; and (3) reviewed if a program's initial rank list, created before scores were known, would be changed before submission for the Match.

Methods
During the 2018–2019 and 2019–2020 recruitment seasons, all programs at a single sponsoring institution were invited to develop selection criteria in the absence of Step 1 data, and to remain blinded to this data throughout recruitment. Participating programs were surveyed to determine factors affecting feasibility and metrics used for residency selection. Once unblinded to Step 1 scores, programs had the option to change their initial rank lists.

Results
Of 24 residency programs, 4 participated (17%) in the first year: emergency medicine, neurology, pediatrics, and psychiatry. The second year had the same participants, with the addition of family and community medicine and radiation oncology (n = 6, 25%). Each program was able to determine mission-specific qualities in the absence of Step 1 data. In both years, one program made changes to the final rank list.

Conclusions
It was feasible for programs to establish metrics for residency recruitment in the absence of Step 1 data, and most programs made no changes to final rank lists after Step 1 scores were known.