bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pentingnya Keterampilan Belajar di Abad 21 sebagai Tuntutan dalam Pengembangan Sumber Daya Manusia
Authors: Rifa Hanifa Mardhiyah  , Sekar Nurul Fajriyah Aldriani  , Febyana Chitta  , Muhamad Rizal Zulfikar  
Published: February 2021

Abad 21 berpusat pada perkembangan Era Revolusi Industri 4.0 yang mengedepankan pengetahuan sebagai tombak utama. Namun, dengan pengetahuan saja tidak cukup untuk mewujudkan Era Revolusi Industri 4.0, karena perlu adanya keseimbangan antara pengetahuan dengan keterampilan sebagai dasar dari sumber daya manusia yang berkualitas pada perkembangan zaman. Mengasah keterampilan melalui pembiasaan diri dan pemenuhan kebutuhan hidup dalam berbagai macam hal yang didasari oleh pengetahuan. Pembelajaran abad ke 21 diharapkan dapat membuka lebih lebar kesempatan kerja dan memperluas lapangan kerja bagi masyarakat Indonesia sebagai sumber daya manusia yang berkualitas dan unggul. Untuk membentuk sumber daya manusia yang berkualitas, maka dibutuhkan tenaga pendidik yang siap mengajar dan mendidik melalui pembelajaran abad 21 yang tentunya diharuskan relevan dengan perkembangan Era Revolusi Industri 4.0. Tujuan dari penelitian ini adalah mengetahui keterampilan belajar yang akan dibutuhkan pada pembelajaran abad 21, dan pengembangan sumber daya manusia yang berkualitas. Penelitian ini menggunakan metode kualitatif deskriptif dengan pendekatan berupa studi pustaka. Hasil penelitian menunjukan bahwa pembelajaran abad 21 berorientasikan kepada kegiatan untuk melatih keterampilan peserta didik dengan mengarah pada proses pembelajaran. Pembelajaran abad 21 berfokus pada student center dengan tujuan untuk memberikan peserta didik keterampilan berpikir diantara lain: (1) berpikir kritis, (2) memecahkan masalah, (3) metakognisi, (4) berkomunikasi, (5) berkolaborasi, (6) inovasi dan kreatif, (7) literasi informasi. Oleh sebab itu diharapkan pendidikan dapat menciptakan sumber daya manusia yang berkualitas dalam bidang teknologi informasi dan juga aspek kemanusiaan karena pembelajaran abad 21 lebih mengintegrasikan terhadap pengetahuan dan keterampilan.
Pengembangan Media Pembelajaran Berbasis Augmented Reality (AR) pada Materi Prosedur Penyimpanan Arsip
Authors: Lifa Farida Panduwinata  , Ruri Nurul Aeni Wulandari  , Mokhammad Nurrudin Zanky  
Published: February 2021

Informasi menjadi salah satu kebutuhan yang mendasar dan sumber pengetahuan bagi setiap orang di era modernisasi seperti saat ini dan arsip merupakan salah satu sumber informasi. Fungsi kearsipan menjadi semakin penting pada saat ini karena arsip merupakan alat bukti akuntabilitas sebuah organisasi. Berdasarkan hasil pengamatan, selama ini yang terjadi dilapangan peserta didik mengalamai kesulitan dalam memahami materi prosedur penyimpanan arsip. Tujuan dari penelitian ini adalah menggabungkan Augmented Reality (AR) ke dalam proses pembelajaran sebagai media pembelajaran, sehingga diharapkan dapat memberikan pengalaman belajar kepada peserta didik tentang konsep atau gagasan abstrak yang mungkin sulit dipahami oleh peserta didik. Dengan menggunakan media pembelajaran ini diharapkan peserta didik akan lebih mudah memahami prosedur penyimpanan arsip. Metode yang digunakan dalam pengembangan media pembelajaran ini adalah Multimedia Development Life Cycle (MDLC) yang bersumber dari Luther dan sudah dimodifikasi oleh Sutopo. Pengembangan media pembelajaran berbasis Augmented Reality (AR) diawali dengan pembuatan konsep, pembuatan desain, pembuatan video animasi, dan pengujian media terkait dengan kemampuan kamera telepon pintar mendeteksi overlays. Berdasarkan hasil pengembangan dan pengujian terhadap media pembelajaran berbasis Augmented Reality (AR) pada materi prosedur penyimpanan arsip dapat dikatakan berhasil. Hal ini sesuai dengan yang diharapkan yaitu untuk mempertajam pengetahuan peserta didik dalam memahami prosedur penyimpanan arip sehingga lebih mudah dalam mempraktikkan sistem penyimpanan arsip.
HUMAN-COMPUTER INTERACTION IN MEDICAL EDUCATION
Authors: Mohamed Mustafa M. A. , Darabee Hatem A. M. , Soykan Emrah 
Published: February 2021

Background: As a pivotal and critical constituent of medical education, notable human-computer interaction (HCI) conduct emphasizes attention for building a domain in which each and every employee develops and excels. HCI, as is always an essential partner in medical field, is here understood as the central idea or the thematic statement of the study.
Aim: The aim is to summarize the analysis of the selected sample into a compound article that move within the circle of human-computer interaction in medical education.
Sample: The study was conducted as a review of 55 articles selected from refined 250 ones, within the concept of technology in medicine in a period of 3 years (2016-2019).
Design and methods: descriptive approach is used through an evaluative analysis, where literature review is considered as a tool for data collection.
MA STUDENTS’ VIEWS ON THE LECTURERS’ USE OF POWERPOINT PRESENTATIONS IN ONLINE LIVE LECTURES DURING THE COVID-19 LOCKDOWN
Authors: Günhan Aslı Kasabalı , Köprülü Fatma 
Published: February 2021

PowerPoint Presentations have been one of the content delivery tools used heavily by the lecturers in online live lectures during the Covid-19 lockdown. They were chosen by the lecturers for the delivery of the lessons with the belief that they provide an effective visual support and organization of the content. However, do students have the same views on the use of PowerPoint presentations? The study aimed to present the views of MA students’ on the lecturers’use of PowerPoint presentations during online live lectures.To meet the aim of this research, qualitative research method was used. Data obtained fromstructured interviews which consisted of 4 open-ended questions. Participants presented their views on the use of Power Point presentations during live lectures in terms of positive and negative sides mentioning the problems, if any, and their suggestions to those problems.The study group was comprised of 16 MA students who were studying at Near East University during the Spring term of the academic year 2019-2020.Results of the research indicated that in MA students’ views, the use of materials presented through PowerPoint proves to be practical in the lesson, offers visual richness while at the same time providing efficient monitoring and evaluation.

Key words: PowerPoint presentations, online live lecture, Covid-19
CONTENT ANALYSIS STUDY FOR THE STUDIES DONE ON PARENTAL EDUCATION
Authors: Sorakın Yasemin , Çerkez Yağmur 
Published: February 2021

The aim of this study is to analyze the studies which were carried out for the education of both mother and father in respect of content analysis. This research is a document review type study. The current study is limited to and analyzed by 150 articles that were published in the database of Web of Science, Scopus, EBSCO and Ulakbim between the years 2008-2018. The articles were evaluated in terms of year of publication, country, method and sample group in accordance with the main objective. Based on this analysis, it was detected that the studies that were carried out regarding the education of mother is higher than the education of father. Furthermore, it was detected that the studies were carried out in the year 2017 mostly. Considering the analyses that were carried out, it was observed that mostly mother, subsequently father and child groups as sample groups were included in these studies. It was also detected that the studies were carried out mostly as quantitative research method. Moreover, it was specified in the reviewed databases that the studies regarding the issues of education of mother and father were implemented in America mostly.

Key Words: Mother’s Education, Father’s Education, Parental Education
ANXIETY AND SUBJECTIVE WELL-BEING RELATIONSHIP IN INDIVIDUALS WITH VISUALLY IMPAIRED PARENTS
Authors: Ulu Ezgi , Haksal Mehmet Eyüp 
Published: February 2021

The aim of this study is to examine the anxiety and subjective well-being levels of individuals between the ages of 18-30, whose mothers and fathers are visually impaired and who do not have any disabilities in themselves. 50 individuals were participated in the study whose both of their parents are visually impaired. Research data were collected using the Beck Anxiety and Subjective Well-being Scale. SPSS 25.0 software was used to analyze the data. As a result of the study, it was found that the congenital condition of the parents’ visual impairment did not make a difference in the registration level of the individuals, but the congenital state of the mother's visual impairment made a difference in subjective well-being. In addition, a negative, weak and significant relationship was found between individuals' anxiety and subjective well-being levels. It is thought that supporting the children of visually impaired parents from birth will play a protective role for the high anxiety they may cause in the future.
Keywords: Visually Impaired, Anxiety, Subjective well-being
EVALUATING THE CONTENT OF TEACHER CANDIDATES’ COURSE BOOKS ACCORDING TO VISUAL DESIGN ELEMENTS
Authors: Demir Burak , Baştaş Mert , Yücesoy Yücehan 
Published: February 2021

Abstract
Textbooks are one of the indispensable materials of educational life, even if the technology has developed, textbooks from past to present are still among the most basic building blocks of education and it can be said that they will continue in this way in the future, and in this research, social studies textbooks taught in schools in the Republic of Turkey and the Turkish Republic of Northern Cyprus are intended to be evaluated by teacher candidates for visual design principles. Alpan (2004) was used in the research, which is the visual design scale of "Graphic/Visual Design Principles Scale for Textbooks". The score of the scale is calculated as "Yes" option is calculated as 2 points, "Partially" option is calculated as 1 point and "No" option is calculated as 0 points. The data obtained as a result of the research were evaluated by scoring between 1-10. According to the result of the evaluation of the teacher candidates from the research, it was determined that the books had different levels of averages according to the scale dimensions but were quite suitable as a general line.

Keywords: Education, Social Studies, Visual Design
EXAMINATION OF GRADUATE THESES CONDUCTED ON PRESCHOOL INCLUSION BETWEEN 2016-2020 IN TURKEY
Authors: Özçelik Mahide , Demirok Mukaddes Sakallı 
Published: February 2021

The aim of this study is to examine the current research trends in graduate theses on preschool inclusion in Turkey. Document analysis technique, one of the qualitative research methods, was used in the research. It was carried out on 31 graduate theses, which were obtained as a result of scanning the thesis archive of the Higher Education Council (YÖK) and were open to access between 2016 to 2020. The search was carried out by typing "pre-school integration" into the search engine of the Higher Education Institution's thesis archive. The theses included in the study were analyzed using the thesis analysis form prepared beforehand by the researchers. In the prepared form, the theses were analyzed according to the year, thesis level, university, institute, department, thesis supervisor title, research model, number of participants, data collection tool, data analysis method, and domestic and foreign references. The findings obtained within the framework of the examination were interpreted with percentage and frequency tables, and recommendations were made for future research.
Key Words: Mainstreaming, preschool, thesis, document analysis.
PENGGUNAAN CLIP (KEPINGAN) PADA MATERI PENJUMLAHAN DAN MENGURANGAN BILANGAN BULAT DALAM MENINGKATKAN AKTIVITAS DAN HASIL BELAJAR MATEMATIKA
Authors: Wirahmad Ika Ika , Kurniawati Kurniawati 
Published: February 2021

Penelitian ini adalah penelitian tindakan kelas yang bertujuan untuk meningkatkan aktivitas dan hasil belajar matematika dengan penggunaan clip(kepingan). Subjek penelitian ini adalah seluruh siswa kelas VIIA SMP Negeri 2 Donggo yang berjumlah 28 orang. Jenis penelitian ini adalah jenis penelitian tindakan kelas dengan Rancangan penelitian yang mengacu pada model penelitian yang dikemukakan oleh Kemmis dan Mc. Taggart (Arikunto, 2008: 16) yang terdiri atas 4 tahapan yaitu (1) perencanaan, (2) pelaksanaan tindakan, (3) observasi/Evaluasi dan (4) refleksi. Pengambilan data di lakukan dengan menggunakan tes hasil belajar dan hasil observasi. Data yang terkumpul di analisis dengan menggunakan analisis kualitatif dan analisis kuantitatif dengan indikator keberhasilannya dikatakan meningkat jika hasil belajar memenuhi KKM minimal ≥65 dan ketuntasan Klasikal ≥85%. Hasil penelitian menunjukan bahwa terdapat peningkatan perolehan skor rata-rata 60 berkategori rendah pada siklus I dan ketuntasan klaksikal mencapai 67,85 meningkat menjadi 85% pada siklus II dengan perolehan skor rata-rata 70 paling rendah pada siklus II dengan ketuntasa klaksikal mencapai 92,85. Ketuntasan klaksikal yang di tetapkan oleh depertemen pendidkan nasional yaitu 85%. Pada siklus I belum memenuhi ketuntasan klaksikal dan terjadi peningkatan pada siklus II sehingga ketuntasan klaksikal terpenuhi. Dapat di simpulkan bahwa penggunaan clip (kepingan) pada materi penjumlahan dan pengurangan bilangan bulat dapat meningkatkan aktivitas dah hasil belajar matematika siswa kelas VIIA SMP Negeri 2 Donggo Tahun Pelajaran 2017/2018
NADPH and Mito-Apocynin Treatment Protects Against KA-Induced Excitotoxic Injury Through Autophagy Pathway
Authors: Liu Na , Lin Miao-Miao , Huang Si-Si , Liu Zi-Qi , Wu Jun-Chao , Liang Zhong-Qin , Qin Zheng-Hong , Wang Yan 
Published: February 2021

AimPrevious research recognizes that NADPH can produce reduced glutathione (GSH) as a coenzyme and produce ROS as a substrate of NADPH oxidase (NOX). Besides, excessive activation of glutamate receptors results in mitochondrial impairment. The study aims at spelling out the effects of NADPH and Mito-apocynin, a NOX inhibitor which specifically targets the mitochondria, on the excitotoxicity induced by Kainic acid (KA) and its mechanism.MethodsThein vivoneuronal excitotoxicity model was constructed by stereotypically injecting KA into the unilateral striatum of mice. Administrated NADPH (i.v, intravenous) 30 min prior and Mito-apocynin (i.g, intragastric) 1 day prior, respectively, then kept administrating daily until mice were sacrificed 14 days later. Nissl staining measured the lesion of striatum and survival status of neurons. Cylinder test of forelimb asymmetry and the adhesive removal test reflected the behavioral deficit caused by neural dysfunction. Determined Total superoxide dismutase (T-SOD), malondialdehyde (MDA), and GSH indicated oxidative stress. Western blot presented the expression levels of LC3-II/LC3-I, SQSTM1/p62, TIGAR, and NOX4. Assessed oxygen consumption rate using High-Resolution Respirometry.In vitro, the MitoSOX Indicator reflected superoxide released by neuron mitochondria. JC-1 and ATP assay Kit were used to detect mitochondrial membrane potential (MMP) and energy metabolism, respectively.ResultsIn this study, we have successfully established excitotoxic model by KAin vivoandin vitro. KA induced decreased SOD activity and increased MDA concentration. KA cause the change of LC3-II/LC3-I, SQSTM1/p62, and TIGAR expression, indicating the autophagy activation. NADPH plays a protective rolein vivoandin vitro. It reversed the KA-mediated changes in LC3, SQSTM1/p62, TIGAR, and NOX4 protein expression. Mito-apocynin inhibited KA-induced increases in mitochondrial NOX4 expression and activity. Compared with NADPH, the combination showed more significant neuroprotective effects, presenting more neurons survive and better motor function recovery. The combination also better inhibited the over-activated autophagy.In vitro, combination of NADPH and Mito-apocynin performed better in restoring mitochondria membrane potential.ConclusionIn summary, combined administration of NADPH and NOX inhibitors offers better neuroprotection by reducing NADPH as a NOX substrate to generate ROS. The combined use of NADPH and Mito-apocynin can better restore neurons and mitochondrial function through autophagy pathway.
Targeting POLE2 Creates a Novel Vulnerability in Renal Cell Carcinoma via Modulating Stanniocalcin 1
Authors: Zhang Chuanjie , Shen Yan , Gao Lili , Wang Xiaojing , Huang Da , Xie Xin , Xu Danfeng , He Hongchao 
Published: February 2021

ObjectiveThe aim of this study is to investigate the biological functions and the underlying mechanisms of DNA polymerase epsilon subunit 2 (POLE2) in renal cell carcinoma (RCC).MethodsThe datasets of POLE2 expression in The Cancer Genome Atlas Kidney Clear Cell Carcinoma (TCGA-KIRC) and International Cancer Genome Consortium (ICGC) databases was selected and the correlation between POLE2 and various clinicopathological parameters was analyzed. The POLE2 expression in RCC tissues was examined by immunohistochemistry. The POLE2 knockdown cell lines were constructed. In vitro and in vivo experiments were carried out to investigate the function of POLE2 on cellular biology of RCC, including cell viability assay, clone formation assay, flow cytometry, wound-healing assay, Transwell assay, qRT-PCR, Western blot, etc. Besides, microarray, co-immunoprecipitation, rescue experiment, and Western blot were used to investigate the molecular mechanisms underlying the functions of POLE2.ResultsPOLE2 was overexpressed in RCC tissues, and high expression of POLE2 was correlated with poor prognosis of RCC. Furthermore, knockdown of POLE2 significantly inhibited cell proliferation, migration, and facilitated apoptosis in vitro. In vivo experiments revealed that POLE2 attenuated RCC tumorigenesis and tumor growth. we also illuminated that stanniocalcin 1 (STC1) was a downstream gene of POLE2, which promoted the occurrence and development of RCC. Besides, knockdown of POLE2 significantly upregulated the expression levels of Bad and p21 while the expression levels of HSP70, IGF-I, IGF-II, survivin, and sTNF-R1 were significantly downregulated. Western blot analysis also showed that knockdown of POLE2 inhibited the expression levels of Cancer-related pathway proteins including p-Akt, CCND1, MAPK9, and PIK3CA.ConclusionKnockdown of POLE2 attenuates RCC cells proliferation and migration by regulating STC1, suggesting that POLE2-STC1 may become a potential target for RCC therapy.
The Association Between Plasma Hyaluronan Level and Plaque Types in ST-Segment–Elevation Myocardial Infarction Patients
Authors: Li Jiannan , Tan Yu , Sheng Zhaoxue , Zhou Peng , Liu Chen , Zhao Hanjun , Song Li , Zhou Jinying , Chen Runzhen , Chen Yi , Yan Hongbing 
Published: February 2021

Background: The metabolism of hyaluronan (HA) is widely known to be involved in the process of acute coronary syndrome, but it is unknown how circulating HA levels change in ST-Segment–Elevation Myocardial Infarction (STEMI) patients and whether HA is associated with plaque morphology, including rupture and erosion.Objectives: This study focused on the changes in the plasma levels of high molecular weight (HMW) HA (&gt;35 kDa) and CD44 in STEMI patients and their relationship with plaque morphology evaluated by optical coherence tomography (OCT).Methods: We prospectively enrolled 3 cohorts in this study, including 162 patients with STEMI, 34 patients with stable coronary artery disease (S-CAD) and 50 healthy controls. Plaque morphology was detected by OCT analysis, and the plasma levels of HMW HA and CD44 were examined by enzyme-linked immunosorbent assay (ELISA). We compared plasma level of HMW HA and CD44 among STEMI patients, S-CAD patients and healthy controls, as well as in plaque rupture and plaque erosion.Results: The plasma levels of HMW HA and CD44 were significantly lower in STEMI patients than in healthy controls (p = 0.009 and p &lt; 0.001, respectively). In addition, plasma level of HMW HA in plaque erosion was significantly lower than that in plaque rupture (p = 0.021), whereas no differences were found in plasma level of soluble CD44 between plaque rupture and erosion.Conclusions: Low levels of circulating HMW HA and CD44 were independently correlated with STEMI, and low levels of HMW HA were associated with plaque erosion compared with rupture. Moreover, plasma HMW HA might be a useful biomarker for identifying plaque erosion to improve the risk stratification and management of STEMI patients.
Tectonic Fabric, Geochemistry, and Zircon-Monazite Geochronology as Proxies to Date an Orogeny: Example of South Delhi Orogeny, NW India, and Implications for East Gondwana Tectonics
Authors: Singh Subhash , De Waele Bert , Shukla Anjali , Umasankar B. H. , Biswal Tapas Kumar 
Published: February 2021

We have dated the South Delhi orogeny, Aravalli-Delhi Mobile Belt (ADMB), NW India, using the tectonic fabric, geochemistry, and zircon-monazite geochronology as the proxies. The South Delhi Terrane (SDT), a passive margin domain in the ADMB, consists of multiply deformed (D1–D4) greenschist facies rocks and several granite plutons. The D1deformation is characterized by pervasive isoclinal recumbent F1fold and axial planar tectonometamorphic fabric, S1, developed in all rock types. The S1minerals belong to peak greenschist facies metamorphism, M1, suggesting syntectonic nature of M1with D1. The age of the D1-M1is constrained by the syncollisional peralkaline S type Sewariya granite which is characterized by magmatic/submagmatic fabric (Sm) coplanar with the S1. The margin of the pluton is turned into quartzofeldspathic gneiss carrying the evidence of high temperature deformation. The age of Sewariya granite is estimated at ca. 878 Ma by zircon geochronology. The D1-M1is further constrained by monazite geochronology of the mica schist at ca. 865–846 Ma. The other granite plutons and metarhyolite are pre-D1and emplaced at ca. 992–946 Ma. The D2deformation produced NE-SW trending open upright F2folds coaxial with the F1, and northwesterly vergent F2–axial planar thrusts. Monazite geochronology constrains the D2at ca. 811–680 Ma. The D3is characterized by small to large scale NW-SE folds, and the D4by faults and fractures marking the brittle deformation in the rocks. The D4is constrained by monazite geochronology at ca. 588–564 Ma. There are upper amphibolitic tectonic slivers along the D2-Phulad thrust, belonging to the pre-Delhi rocks, which show ca. 1,638 Ma metamorphism age. From the above study, it is suggested that the South Delhi orogeny belongs to ca. 878–680 Ma marking the final amalgamation of Marwar Craton with the rest of India. This overlaps the early phase of the Pan-African orogeny (900–630 Ma). The brittle deformation, D4, coincides with Kuunga orogeny (650–500 Ma). Our study implies that India, like other continents in the East Gondwana, underwent amalgamation of internal blocks until the late part of the Neoproterozoic.