bluuebunny/crossref_metadata_2025_split huggingface dataset:
Protistátní trestné činy v moderních kodifikacích
Authors: Kolumber David 
Published: December 2021

The contribution “Anti-state Crimes in Modern Codifications” deals with the topic of anti-state crimes during centuries. Firstly, legal concepts in the pre-state period are mentioned. Then the attention is paid on the evolution of this institute in the Euro-Atlantic area. From this point of view, there are mentioned mainly regulations from England (1351), France (1810), Germany (1871) and Soviet Union (1958) which could be remarked as the most important for the development of other countries. On the other hand, it also reminds the development of codifications in Czechoslovakia, the Czech Republic and Slovakia, which were affected by the Austro-Hungarian legislations as well as German and Soviet approaches. The Czech current arrangement generally does not depart from the other European samples, but it cannot be omitted that in the Czech Republic it is distinguished the penal concept of the high treason (Landesverrat, vlastizrada) from the constitutional concept (Hochverrat, velezrada) which is dedicated to the presidential anti-state activities. The contribution also indicates that the concept of anti-state crimes in countries has not been unified and it has been varying according to various experiences and attitudes.
Poznámky o ušlechtilém muži, „lejstrech“ a trochu také o protistátních trestných činech
Authors: Vojáček Ladislav 
Published: December 2021

The paper deals with the criminal law education at the turn of the 19th and 20th century. It focuses on person of professor František Štorch, teaching criminal law at the Czech Law Faculty of Karl-Ferdinand University in Prague at that time. It pays its attention to the form of the then used learning tools as well as to the integration of crimes against the state into the system of criminal law back then.
Cross-cultural adaptation of the Brazilian version of the Athlete Sleep Behavior Questionnaire
Authors: Facundo Lucas Alves , Albuquerque Maicon Rodrigues , Esteves Andrea Maculano , Driller Matthew W , Grade Isadora , De-Mello Marco Túlio , Silva Andressa 
Published: December 2021

Introduction: Considering the specificity of the sporting context and the influence of sleep on athletic performance, the “athlete sleep behavior questionnare” (ASBQ) was developed to evaluate sleep behavior in English-speaking athletes.
Objective: The aim of this study was to perform a cross-cultural adaptation and validation of the ASBQ in Brazilian athletes.
Methods: The cross-cultural adaptation was processed by procedures of translation and back-translation. Content validity was performed by 9 experts, calculating the coefficient of content validity for the equivalence of the individual items (Cvci) and the total global score (Cvct), in addition we conducted a pilot study using the translated version of the questionnaire. The next phase of the study included 52 athletes completing the translated ASBQ. The reliability of the questionnaire was assessed by the intraclass correlation coefficient (ICC), standard error of measurement (SEM) and by Cronbach’s alpha (α).
Results: The ASBQ passed the process of cross-cultural adaptation, obtaining the Brazilian Version of the ASBQ (ASBQ-BR), and with acceptable values of Cvci (0.89-1.00) and Cvct (0.96). Additionally, the ASBQ-BR showed acceptable values of reliability (ICC=0.857; Cronbach’s α=0.78) and a SEM of 3.05 AU.
Conclusion: The ASBQ was translated to a newly developed ASBQ-BR, resulting in acceptable values for content validity and reliability. The ASBQ-BR provides a valuable tool for monitoring sleep behaviors in Brazilian athletes.
Pregabalin abuse and dependence during insomnia and protocol for short-term withdrawal management with diazepam: examples from case reports
Authors: Papanna Basavaraja , Lazzari Carlo , Kulkarni Kapil , Perumal Sivasankar , Nusair Abdul 
Published: December 2021

Introduction: Pregabalin (PGN) is an anxiolytic, analgesic, antiepileptic, and hypnotic medication. There are concerns about its abuse in the community for managing chronic insomnia and other risks when assumed in overdose or combination with other abuse substances. PGN is classified as a controlled medication. While its discontinuation is accompanied by rebound insomnia and other neurological symptoms, cross-tapering PGN with short-term diazepam (DZ) during inpatient admissions has shown promising results in dealing with PGN withdrawal symptoms accompanied by rebound insomnia.
Material and Methods: We report three cases that began abusing their prescribed PGN. During hospital admission, our teams used a protocol for cross-tapering PGN with DZ to reduce withdrawal symptoms. Other sedative medications are suspended while alcohol is not allowed if patients are on leave from the hospital. Standardized scales for assessment were clinical global impression scale-severity (CGI-S), generalized anxiety disorder scale (GAD-7), and insomnia severity index (ISI).
Results: The cross-tapering PGN with DZ showed similar clinical outcomes with reduced withdrawal symptoms and rebound insomnia during two weeks of cross-tapering. Eventually, DZ, too, is stopped in the hospital to avoid another dependence syndrome.
Conclusion: As emerging in the current study, PGN has strong addictive effects in people who have insomnia and is mostly abused for its hypnotic or sleep-inducing properties when other medications have failed. As applied in the current study, DZ can manage PGN withdrawal symptoms with rebound insomnia while cross-tapering. DZ is then discontinued.
Competencia digital, actitudes y expectativas hacia las tecnologías digitales. Perfil de los futuros maestros de primaria
Authors: Llopis Nebot María Ángeles , Santágueda Villanueva María , Esteve Mon Francesc Marc 
Published: December 2021

Este estudio pretende trazar un perfil del alumnado que cursa el Grado de Maestro en Educación Primaria en relación a sus hábitos en el uso de las tecnologías digitales, la percepción sobre su competencia digital, así como de las expectativas y actitudes hacia el uso de la tecnología en su ámbito personal y académico. Se realiza asimismo una comparación entre alumnos pertenecientes a dos planes de estudios distintos. Los datos se obtienen mediante el cuestionario INCOTIC 2.0. Tras el análisis de datos se evidencia el alto uso que hacen de la tecnología a través de dispositivos móviles y portátiles, especialmente en el ámbito de las relaciones sociales. Se muestra una buena actitud hacia el uso académico de la tecnología y una favorable expectativa de uso. En cuanto a la percepción de la competencia digital, destacan en las alfabetizaciones comunicativa y multimedia. Comparando ambos grupos, no se observan diferencias significativas en la mejora de la competencia digital, estas se limitan al ámbito comunicativo, las actitudes y las expectativas que tiene el estudiantado hacia las TIC. De acuerdo con los resultados, se propone incidir en la mejora de las áreas informacional y tecnológica, ambas fundamentales para su desarrollo profesional docente.
This study aims to draw a profile of the students who are studying the Bachelor's Degree in Primary Education in relation to their habits in the use of digital technologies, the perception of their digital competence, as well as the expectations and attitudes towards the use of technology in their personal and academic environment. A comparison is also made between students belonging to two different study plans. The data is obtained through the INCOTIC 2.0 questionnaire. After data analysis, the high use they make of technology through mobile and portable devices is evident, especially in the field of social relationships. In addition, there is a good attitude towards the academic use of technology and a favorable expectation of use. Regarding the perception of digital competence, they stand out in communicative and multimedia literacies. However, in the comparison of both groups, no significant differences are observed in the improvement of digital competence, and these are limited to the communicative field of these technologies, attitudes and expectations that the students have towards digital technologies. According to the results, it is proposed to influence the improvement of the informational and technological areas, both vital for their teaching professional development.
Covid-19: La brecha (digital) educativa a través de la prensa
Authors: Suárez Lantarón Belén , García-Perales Nuria 
Published: December 2021

La situación socio-sanitaria ocasionada por la COVID-19 ha implicado la clausura de los centros educativos forzando a la población escolar a continuar su proceso de enseñanza-aprendizaje de forma virtual. Esta situación ha puesto en evidencia la brecha digital existente entre los escolares, una realidad que ha aflorado en toda su magnitud para convertirse en objeto y tema de debate en el ámbito periodístico. Este trabajo tiene por objetivo describir el alcance de la brecha digital en el ámbito educativo y sus consecuencias, así como las posibles soluciones a corto y largo plazo. La metodología elegida es de carácter cualitativo apoyada en el análisis de contenido, en la que se exploran y revisan publicaciones de prensa generalista española en el primer mes de confinamiento, tanto de ámbito nacional como autonómico. Los resultados muestran que la prensa aborda el desequilibrio y desigualdad social respecto al acceso a la información y las dificultades consecuentes para acceder a la modalidad online, se observa un claro interés por la brecha digital, principalmente de acceso a internet, como una más de las dificultades en entornos socio-económicos vulnerables para acceder a la educación en igualdad de condiciones. Como conclusión cabe destacar que la pandemia, a través de la prensa generalista, ha incrementado la visibilidad de una situación ya existente: la desigualdad digital. Una desigualdad que favorece la exclusión en una sociedad que se muestra eminentemente tecnológica.
The socio-sanitary situation caused by COVID-19 has implied the closure of educational centers, forcing the school population to continue their teaching-learning process virtually. This situation has highlighted the existing digital divide between schoolchildren, a reality that has emerged in all its magnitude to become an object and topic of debate in the journalistic field. This work aims to describe the scope of the digital divide in education and its consequences, as well as possible solutions in the short and long term. The chosen methodology is of a qualitative nature supported by content analysis, in which general Spanish press publications are explored and reviewed in the first month of confinement, both nationally and regionally. The results show that the press addresses the social imbalance and inequality regarding access to information and the consequent difficulties in accessing the online modality, there is a clear interest in the digital divide, mainly internet access, as one more of the Difficulties in vulnerable socio-economic environments to access education under equal conditions. In conclusion, it should be noted that the pandemic, through the generalist press, has increased the visibility of an already existing situation: digital inequality, which favors exclusion in a society that is eminently technological
Percepciones en torno a una educación remota y a una educación híbrida universitaria durante la pandemia de la COVID-19: estudio de caso
Authors: Balladares Burgos Jorge 
Published: December 2021

El presente artículo tiene como propósito realizar un estudio sobre las percepciones en torno a una educación remota y a una educación híbrida en la educación superior. El estudio de caso de un programa universitario de posgrado se articula con el enfoque de la investigación basada en el diseño para analizar percepciones sobre una educación remota en tiempos de pandemia e identificar factores claves de éxito para una nueva normalidad educativa a partir de los microciclos de la fase de implementación. Entre los hallazgos, se reconoce que una educación remota respondió a la emergencia de la pandemia y se identificaron factores claves de éxito tales como la temporalización del proceso de enseñanza y aprendizaje, la docencia sincrónica, el diseño tecnopedagógico de los entornos virtuales de aprendizaje, y la transformación digital universitaria. Estos resultados permiten resignificar el concepto tradicional de educación híbrida incorporando fortalezas de la educación remota, y reposicionándola como una modalidad de estudio estratégica para una nueva normalidad educativa que recupere progresivamente la presencialidad y expanda el aprendizaje de los estudiantes. La presente investigación contribuye a plantear pistas desde la educación híbrida hacia una renovada educación postpandemia.
The purpose of this article is to lead a case study on perceptions around remote education and hybrid education in higher education. The case study of a graduate university program is articulated by the design-based research approach for analyzing perceptions about remote education in the Covid-19 pandemic and to identify key success factors for new educational normality through the microcycle of análisis and exploration. Among the findings, it is recognized that remote education responded to the emergency of the pandemic and identified key success factors such as teaching and learning timing, synchronous teaching, instructional design of virtual learning environments, and digital transformation in universities. These results allow us to re-signify the formal concept of blended learning including key strengths of remote learning and consider it as a strategic learning model for new higher education normality that will progressively recover face-to-face classrooms and expand students’ learning. This research contributes to raising clues from blended learning to renovate post-pandemic education
« Performance » et pratique professionnelle dans les services de soutien à domicile offerts aux aînés : effets et actions possibles pour assurer un développement durable
Authors: Carrier Annie 
Published: December 2021

La reddition de compte et l’optimisation de la performance visent à améliorer la performance des services de soutien à domicile (SSAD) mais ne semblent pas avoir les effets escomptés. Le manque de latitude décisionnelle des professionnels et, conséquemment, leur réactivité insuffisante seraient en cause. Cette réactivité relève pourtant du rôle d’agent de changement, encore peu investi. Cet article poursuit trois objectifs : 1) Synthétiser les connaissances sur le rôle de la reddition de compte et de l’optimisation de la performance dans la pratique des professionnels des SSAD ; 2) Décrire le rôle d’agent de changement ; et 3) Explorer son enseignement.
Assessing the Information Seeking Behavior of Urban Farmers to Design an Integrated Extension Model
Authors: Abraham Anju , Arunachalam R. 
Published: December 2021

Even though the urbanisation is considered as a development indicator, the tremendous migration from rural areas to urban areas leads to serious environmental, health and economic issues. Due to the space and time constraints, the urban entity used to depend on rural community for their food products. But in the same time, highly priced demand for land and the lesser profit from farming results in withdrawal of rural farmers from farming. And these above mentioned factors contributed to a gap in supply and demand for food. This gap leads to the non-availability of nutritious food and thereby, made difficult for urban dwellers to access it due the high price. And the result was seen as a double burden in the form of malnutrition and obesity among urban dwellers. The concept of Urban Farming can bring back the traditional homestead farming culture and more than that, a nutritionally secured and environmentally sustainable society. As most of the urban dwellers are new to this setup, they need information and assistance for bring it in a successful way. Hence, there is a necessity for understanding their information needs, and the sources currently they are depending. The present study focuses on the information seeking behaviour and its utilisation constraints experienced by the farmers in an urban community. The study was carried out in the period from December 2020 to March 2021 in Ernakulam and Calicut districts which ranks first and third in degree of urbanisation in Kerala respectively. From the findings of the study it is understood that, their information needs varies from the selection of nutritious food crop to marketing of surplus quantity produced. The constraints analysis could give suggestions for improvement and it can narrow down the gap between farmers - extension system. Based on this, an integrated urban farming extension model has been designed for the effective information dissemination to the farmers. This can save time of farmers and efforts of extension agents, and it will motivate them towards potential adoption of more technologies.
Effect of Kalanchoe crenata Extract on Renal and Liver Impairment, Dyslipedemia and Glycemia in Streptozotocin Induced Diabetic Rats
Authors: Effah-Yeboah Emmanuel , Dartey Emmanuel , Asare Emmanuel Agyapong , Abraham Janice Dwomoh , Kagya-Agyemang James K. , Iddrisu Balali Gadafi , Aboagye Vincent 
Published: December 2021

Introduction: Diabetes mellitus or diabetes is a metabolic ailment which occurs as a result of insulin insufficiency or defect in insulin function, or both that leads to ihyperglycemia. Diabetes mellitus is a worldwide disease even though its prevalence in other countries vary. Kalanchoe crenata belongs to the family crassulaceae. It is also known locally as miracle plant and often utilized in Africa for medicinal purposes. The study was designed to ascertain the antidiabetic and dyslipidemic activity and effects of the ethanolic extract of both leaves and stem of Kalanchoe crenata on istreptozotocin incite diabetic rats for three (3) weeks.
Methodology: 6-8 weeks old Sprague dawley rats received multiple injection of streptozotocin intraperitoneally (40mg/kg body weight) to induce diabetes melitus. Diabetes mellitus was observed and confirmed after six days of induction. The rats were given ethanolic extract of Kalanchoe crenata remarkably (10, 30 and 100mg/kg) and 5mg/kg glibenclamide orally twice daily for three weeks. Blood glucose, lipids, creatinine, urea, were then determined.
Results: After week three of treatment 5mg/kg glibenclamide, 30 and 100mg/kg ethanolic extract of Kalanchoe crenata remarkably (p<0.05) decrease glycemia and improved lipidemia by decreasing overall cholesterol, LDL-C and increasing HDL-C likened to the control diabetic group. Also results from treated rats remarkably decrease blood urea nitrogen and creatinine. However, the affirmative control and the sampled treated groups showed curative and regenerative effect in the cells responsible for producing endocrine insulin “beta cells of the islets of Langerhans” located in the pancreas. Kidney and liver tissue sections of treatment groups showed a reversal of diseased insults made by the streptozotocin.
Conclusion: The outcome of the research indicate that given ethanolic extract of Kalanchoe crenata remarkably contains the necessary phytochemicals for the development of a standard and effective herbal medicine for Diabetes mellitus and related complications and also with no toxic effects on the tissues of the liver, pancreas and kidney.
In silico Molecular Docking Analysis of Imatinib to Target the Marker Proteins of Breast Cancer
Authors: Kumar V. Senthil , Kumar T. V. Ajay , Parthasarathy V. 
Published: December 2021

Cancer is an uncontrolled over growth of abnormal cells elsewhere in the body. It is the second leading cause of death globally due to non communicable disease. Among the various types of cancers, the incidence of breast cancer is next to lung cancer. The most commonly used drugs to treat breast cancer are namely, Anastrozole, Arimidex, Letrozol, Imatinib, Tamoxifen, Raloxifene, Toremifene and so on. The hope is to establish the specificity of the drug Imatinib towards the selective potential breast cancers such as mammalian target of rapamycin, (mTOR), human epidermal growth factor receptor 2 (HER2), estrogen receptor (ER), poly (ADP-Ribose) polymerase (PARP) and phosphoprotein 53 (p53). To identify the promising target, the Schrodinger software was utilized for the study. The study helped to evaluate the pharmacokinetic properties and binding efficiency of Imatinib towards the breast cancer proteins. The results of study showed that the Imatinib exhibited better binding affinities to mTOR and HER2 as compared to ER, PARP and P53 proteins. The present study will be more useful to rationalize the anticancer therapy based on the expression levels of the target protein in the cancer microenvironment.
Antioxidant Potential of Crude Methanol Leaf extract and Fraction of Mallotus oppositifolius
Authors: Onyeka Ifeanyi Peter , Onyegbule Felix Ahamefule , Ezugwu Christopher Obodike , Jeremiah Ike Chibueze , B. Ikeotuonye Chidalu 
Published: December 2021

Mallotus oppositifolius (Geiseler) Mull. Arg. (Euphorbiaceae) is a predominant edible shrub in Nigeria. It is locally used for treatment of common infections and wounds. This study evaluated the toxicity and antioxidant potential of the crude extract and fractions of M. oppositifolius using invitro 1,1-diphenyl-2-picrylhydrazine (DPPH) radical scavenging assay. The result showed abundance of flavonoids (28.21), tannins (17.72), alkaloids (7.79) and Saponins (0.23) in the crude extract of M. oppositifolius leaf extract. Also, the result showed that the LD50 is above 5000 mg/kg, therefore the crude extract is safe for consumption. The result further showed that the ethyl-acetate and butanol had significant (p<0.05) antioxidant activity when compared with the control at 125, 62.5 and 31.125 µg/ml respectively while at 250 and 500 µg/ml there was no significant different in the level of reduction of oxidation between the butanol and ethyl acetate when compared with the control. The result further showed that the butanol and ethyl-acetate fraction of M. oppositifolius had the best antioxidant potential among the fractions studied.
The result of GCMS studies of ethyl-acetate fraction showed the presence of 7,10,13-eicosatrienoic acid methyl ester, korormicin, agosterol, phyllanthin, ricinoic acid, 2,4,6-decatrienoic acid 1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9, limonin, com-pounds that have shown to possess strong antioxidant activities. Also, the GCMS result of butanol fraction showed the presence of seven compounds which include: ferulylhistamine, hippeastrine, 10,13-eicosadienoic acid methyl ester, ethyl 5,8,11,14-eicosatetraenoate, 6-hydroxy-powelline-N-nitroso-7-demethoxy-aldehyde, 6,7-epoxypregn-4-ene-9,11,18-triol-3,20-dione 11,18-diacetate and 5Alpha-androstane-3,17-dione 17-monooxime, compounds which may serve as a new lead for the treatment of diseases associated with the oxidative stress.