bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biotransformation of <i>n</i>-butanol to Fruity-Like Bio-Flavour by Indonesian Lactic Acid Bacteria
Authors: Setiyoningrum Fitri , Adi Deddy Triyono Nugroho , Priadi Gunawan , Wibowo Des Saputro , Octaviana Senlie , Afiati Fifi , Fidriyanto Rusli , Prasetyo Doni Dwi , Siregar Abdul Rahman , Vincentlau Dharma 
Published: January 2025

Microbial production of aroma compounds is a promising alternative to extracting plants or chemical synthesis. In our research, the Indonesian lactic acid bacteria (LAB) have been utilised as producing fruity-like bio flavour by biotransformation approach using n-butanol as a precursor. The aims of our research are to identify LAB- secondary metabolites categorised fruity-like bio flavour and investigate the changes of glucose, mannitol, xylose, lactic acid and acetic acid in growth medium after fermentation. Our result research showed that n-butanol could be transformed to several fruity like bio flavour such as ethyl butyrate, butyl acetate, butyl formate, ethyl 2-methylbutanoate, ethyl 3-methylbutanoate, 2-heptanone, butyl propanoate, butyl propanoate, butyl 2-methylbutanoate, butyl isovalerate, butyl pentanoate, and butyl hexanoate. All of LABs consumed above 75% of glucose and only Lactococcus lactis KGB1 consumed all the mannitol on fermentation medium. In addition, Lactococcus lactis KGB1 produced the highest xylose, 11.87 g/L LABs produced. Based on the amount of fruity-like bio flavour compound generated, Lactobacillus fermentum WKS2, Lactobacillus fermentum KGL2, Lactococcus lactis KK4, Lactobacillus fermentum WKS3, Lactococcus lactis KGB1, and Lactobacillus fermentum KGL7 could be considered as agent fruity-like bio flavour by biotransformation approach.
Prevalence of Diagnosed Diabetes Among U.S. Adults Aged ≥18 Years With Disabilities, 2021–2022
Authors: Bardenheier Barbara H. , Omura John D. , Saaddine Jinan B. , Hora Israel , McKeever Bullard Kai 
Published: January 2025

OBJECTIVE
To compare the prevalence of diagnosed diabetes among U.S. adults with and without disabilities, overall and by subgroups.

RESEARCH DESIGN AND METHODS
We used data on adults aged ≥18 years from the cross-sectional 2021–2022 National Health Interview Survey to report the prevalence of diagnosed diabetes by functional disability status and for each disability type (hearing, seeing, mobility, cognition, self-care, and communication) separately. With use of the Washington Group Short Set on Functioning indicator, disability was defined according to the categories of milder (reporting some difficulty), moderate (reporting a lot of difficulty), and severe (cannot do at all) by disability type. Crude prevalence and age-standardized prevalence of diabetes were also calculated for adults with any difficulty with any disability by age, sex, race/ethnicity, education, insurance, and poverty-to-income ratio.

RESULTS
Diabetes prevalence increased with number of disability types, was lower among adults with no disability (5.8%) than among those with milder (9.5%) or moderate to more severe (18.3%) disability, and was 4.0–10.3 percentage points higher among those with moderate to more severe disability than among those with milder disability for vision, hearing, mobility, and cognitive disabilities. Diabetes prevalence was similar for adults with milder and moderate to more severe self-care and communication disabilities.

CONCLUSIONS
Prevalence of diabetes was higher among adults with any functional disability than without and increased with increasing number of disability types. Adults with multiple disability types, or those who have difficulty with self-care or communication or other moderate to more severe disabilities, may benefit from diabetes prevention programs.
Influence of tibial plateau angle in cranial cruciate ligament–deficient stifle on patellar ligament strain: an ex vivo study
Authors: Bester Elizabeth G. , Zeiler Gareth E. , Stoltz George G. , Oberholster Abraham J. , Kitshoff Adriaan M. 
Published: January 2025

Abstract

OBJECTIVE
The aim was to investigate the patellar ligament strain with varying degrees of tibial plateau angles (TPAs) after tibial plateau leveling osteotomy (TPLO) in a cranial cruciate ligament (CrCL)-deficient stifle during the stance phase.

METHODS
12 pelvic cadaver limbs were secured to a custom-built jig to mimic a loadbearing stance after which an axial load of 120 N was applied. Patellar ligament strain, change in strain, and percent change in strain were calculated on pre-TPLO (intact and transected CrCL) and post-TPLO tibial TPAs of −5°, 0°, 5°, 10°, and 15°. Strain was measured using a 3-D digital image correlation to calculate Green-Lagrange strain (E33). Data were compared using a linear mixed model and applying the Dunnett method of multiple comparisons (control was pre-TPLO intact CrCL).

RESULTS
The post-TPLO TPAs of 0° and 5° increased in patellar strain compared to pre-TPLO intact CrCL constructs, whereas no significant changes were seen at a TPA of −5°, 10°, and 15°. Significant changes in patellar ligament strain were noted at a TPA of 0° and 5°. The percent change in strain differed at −5°, 0°, and 5° TPAs. The median magnitude of percent change in strain was 35.1%, 37.0%, 79.0%, −7.1%, and −21.1% for −5°, 0°, 5°, 10°, and 15°, respectively.

CONCLUSIONs
Significant increases in patellar ligament strain (CrCL-deficient stifle) during the stance phase were observed at TPAs of 0° and 5°.

CLINICAL RELEVANCE
A TPA post-TPLO > 5° and < 15° is less likely to cause an increase in patellar ligament strain; however, further research is needed to investigate the clinical relevance of these findings.
Torsemide can be used for long-term management of congestive heart failure in equids: a description of 12 cases (2019–2024)
Authors: Shroff Kavita , Stefanovski Darko , Reef Virginia B. , Kraus Marc S. , Solis Cristobal Navas de 
Published: January 2025

Abstract

OBJECTIVE
Information about congestive heart failure (CHF) treatment in the horse is limited. Torsemide, an oral loop diuretic, is increasingly used in humans, dogs, and cats with CHF. Torsemide is well absorbed and induces diuresis in healthy horses, and its use in a horse with CHF has been reported. This retrospective descriptive study aimed to describe the use of torsemide in equids with CHF.

ANIMALS
12 equids (10 horses, 1 miniature donkey, and 1 mule).

CLINICAL PRESENTATION
Horses presented to a referral practice with clinical signs of congestive heart failure. Diagnosis was confirmed with echocardiography. Treatment with torsemide as well as other cardiac medications was instituted. The cases were evaluated and monitored with physical examinations, clinicopathologic data, and repeat echocardiograms.

RESULTS
Torsemide (PO, q 12 h [median 0.5 mg/kg; IQR, 0.5 to 0.5 mg/kg; range, 0.25 to 1 mg/kg]) was well tolerated in the 12 cases. There were improvements in heart rate and respiratory rate and increases in plasma creatinine concentration (median, 1.3 vs 1.9 mg/dL) that followed therapeutic interventions that included torsemide. Median survival time of equids with CHF treated with torsemide was 189 days (IQR, 10 to 348.25 days; range, 2 to 806 days), with 2 distinct clusters. Four cases were euthanized within 2 weeks after starting treatment, while 8 survived longer than 137 days or are currently alive.

CLINICAL RELEVANCE
Torsemide can be used in equids diagnosed with CHF without serious adverse events and has the potential to be a useful oral diuretic. The nature of the study does not allow us to conclude that torsemide had a causal relationship with clinical progression.
Artificial intelligence is beginning to create value for selected small animal veterinary applications while remaining immature for others
Authors: Albergante Luca , O’Flynn Ciaran , De Meyer Geert 
Published: January 2025

Abstract
Artificial intelligence is a powerful technology with great potential to support veterinarians across many aspects of their multifaceted job. However, realizing this potential requires AI solutions that truly address specific pain points. Here we review 4 use cases in which AI has been applied to small animal veterinary medicine: image analysis, early disease detection, administration support, and disease surveillance. For each of these, we briefly present the current state of the technology and available AI applications. Results show that tangible value creation is heterogeneous across use cases and that availability of accurate and reliable data (eg, in the form of curated electronic health records) is a major limiting factor.
So, why Tartu?: Reflections on semiotics, praxis and international student (night)life
Authors: Murdeshwar Rahul 
Published: January 2025

Abstract
Tartu holds a special place in the history and education of semiotics and draws students from around the world. Semiotics is a learnt way of thinking and being, and so an induction into the field for international graduate students in Tartu is inseparable from its lived experience. This paper describes an account of living semiotics as a foreigner in Tartu, through its application to a personal field of interest, i.e. local underground nightlife and electronic dance music cultures. Besides offering strands of an analytical conception of nightlife and dance music cultures, this paper also reflects on students’ extracurricular commitments in this field to a cultural and artistic practice of applied semiotics.
The Image that Does Not Represent: Mythological Approach
Authors: Sabitov Daniyar 
Published: January 2025

Abstract
Can an image not signify? This paper explores two cases: self-referential images and mythological images. While Winfred Nöth defends the universality of semiotics against a potential paradox, this paper argues that subjection to semiotic logic can distort the understanding of domains such as myth. Mythological images do not adhere to formal logic and lack distinct signifiers and signified. By studying myth from within, without attempting to interpret it through external frameworks, the unique asemiotic nature of the identity between subject and object is revealed.
O Corpo Revivido: Memórias “Pós”-Covid
Authors: de Freitas da Silva Claudinei Aparecido 
Published: January 2025

Abstract
The work is composed of two mutually structuring moments. First, it briefly and critically reconstructs the broader spectrum of the health crisis surrounding Covid-19 that came to light in 2019 and which, in a distant or more recent period, received unique attention in the literary work of Shakespeare and Camus. Second, it provides an account of an experience in which the author, once a victim of the pandemic, retains memories that still have a therapeutic impact on the post-hospital period. Broadly speaking, by looking at this double and mutual record, the text advocates the thesis that such memories are an invitation to permanent reflection without, however, losing sight of another way of life as a possible utopia, whether as a diagnosis or as an antidote to the crisis. From this perspective, Merleau-Ponty’s mature work becomes, in particular, an indispensable guide as a backdrop in this scenario by bringing to light the symptomatically dazzling aspect of the human condition and its ills. The ongoing project of a nouvelle ontologie, in the philosopher’s final itinerary, emblematically circumscribed as “ontological rehabilitation of the sensible,” embraces, in turn, this task and commitment. It is, in short, a philosophy thought from the deepest dimension of our carnality, an experience of thought archaeologically rooted as intertwined with life and, therefore, not indifferent to pain and suffering. It is to this extent that the reflection contains, as a final proposition, the premise that the marks left, in flesh and blood, in the light of the revived experience of the body, greatly prospect a horizon of meaning to be better understood and reconstructed.
Determination of Thermal Physical Characteristics of the Panasonic NCR18650b Lithium-Ion Power Supply Element
Authors: Lazarenko Oleksandr , Pazen Oleg , Velykyi Yarema , Parkhomenko Ruslan , Stepaniak Yurii 
Published: January 2025

Abstract
The purpose of the work was to determine the thermophysical characteristics of Panasonic NCR18650B (LiNi0.8Co0.15Al0.05O2) batteries under the condition of an external heating source. Obtaining the appropriate thermophysical characteristics of lithium-ion battery (LIB) cells can be confirmed by experimental studies and mathematical calculations. Obtaining relevant results in the future makes it possible to carry out a professional assessment of the heating temperature of such LIB, the conditions of their combustion, and the spread of fire in general. According to the results of experimental studies, namely, under the condition of the action of an external source of high temperature (flame) and uniform heating of the outer walls of the LIB, its inner part is heated to an average temperature of 168 °C for 70 seconds. For comparison, the corresponding temperature in the middle of the LIB without internal filling (cathode and anode) is reached within 45 seconds. The developed mathematical model based on the differential equation of thermal conductivity in the cylindrical coordinate system and the use of the Newton-Richmann`s Law of Heat Exchange made it possible to carry out mathematical modelling of the heating process of a LIB. Further comparison of the experimental values with the mathematical model confirmed the correctness of the experiment. The obtained mathematical model based on the experimental values made it possible to obtain the corresponding numerical values of the specific heat capacity, material density, thermal conductivity coefficient and heat exchange between the surface and the near-surface layer of the Panasonic NCR18650B.
Cancer Risk Factors Awareness in Slovenian Adolescents
Authors: JARM Katja , ŠAJN Eva , HADŽIĆ Enej , JURAK Gregor , KRAJC Mateja , IVANUŠ Urška , BUT-HADŽIĆ Jasna 
Published: January 2025

ABSTRACT

Aim
To evaluate Slovenian adolescents’ awareness of common cancer risk and protective factors, identifying knowledge gaps to develop targeted health education initiatives.

Methods
A cross-sectional questionnaire survey was conducted among 795 students aged 13 to 19 years in primary and secondary schools in Slovenia. The responses were analysed using descriptive and analytical statistics. The relationship between educational level, age and gender and awareness of selected cancer risk factors was analysed performing univariate and multivariate logistic regression.

Results
Overall, adolescents demonstrated good awareness of certain risk factors such as smoking (98%), sun exposure (90%) and physical activity (87%). Significant knowledge gaps were identified regarding dietary factors. While 49% recognized red meat consumption as a risk factor, knowledge of protective fruit and vegetable consumption and alcohol consumption as a risk was relatively low at 14% and 38%, respectively. Gender differences were found, with boys better at recognising smoking (p=0.025) and girls better at recognising alcohol (p<0.001). Older students were less aware of the importance of fruit and vegetable consumption (p<0.001), and secondary school students were less aware of the importance of healthy body mass, red meat and alcohol consumption (all p<0.001).

Conclusion
Slovenian adolescents have varied knowledge of cancer risks, showing both strengths and areas for improvement in preventive education. We have identified important gaps in knowledge about diet and alcohol consumption, particularly among older, secondary school students and boys, where targeted interventions can have a major impact on promoting healthier lifestyles and reducing future cancer risks.
Epidemiology and Risk Factor Analysis of Systemic Allergic Reaction to Bee Venom in the Slovenian Population of Beekeepers
Authors: CARLI Tanja , LOCATELLI Igor , KOŠNIK Mitja , BEVK Danilo , KUKEC Andreja 
Published: January 2025

ABSTRACT

Objectives
To estimate the lifetime prevalence of first and recurrent systemic allergic reaction to bee venom among Slovenian beekeepers. Additionally, we aimed to elucidate the risk factors predisposing beekeepers to developing systemic allergic reaction to bee venom.

Methods
A nationwide cross-sectional study was conducted among 1,080 beekeepers who are members of the Slovenian beekeeper’s association, between 1 November 2021 and 31 May 2023. Epidemiological data were collected using a validated questionnaire, with the clinician-confirmed observed health outcome.

Results
The estimated overall lifetime prevalence of self-reported first systemic allergic reaction to bee venom was 9.4% (102/1,080), with 40.7% (24/59) of the clinician-confirmed cases being severe (grade III-IV according to the Mueller classification). The estimated overall lifetime prevalence of reported recurrent systemic allergic reaction to bee venom was lower at 3.7% (40/1,080), with 60.0% (9/15) of the clinician-confirmed cases being severe (grade III-IV according to the Mueller classification). Risk factors associated with the first systemic allergic reaction to bee venom included age, male sex, number of bee stings per season, a history of large local reaction and experiencing nasal symptoms while working at hives. Younger male beekeepers, with a low number of bee stings per season, a history of large local reaction and nasal symptoms while working at hives, are at a high risk of having systemic allergic reaction to bee venom.

Conclusions
High lifetime prevalence of clinician-confirmed severe first and recurrent systemic allergic reaction to bee venom underscored the importance of targeted public health strategies and clinical interventions to protect this high-risk population.
Exploring General Practitioner Work in Upper Austria: A Pilot Retrospective Observational Study Across Thirty Practices
Authors: ZELKO Erika , PEINBAUER Thomas , VOGGENBERGER Lisa , BEKELAER Fabian , PANTOGLOU Julia , STÜBL Denise , REBHANDL Erwin 
Published: January 2025

ABSTRACT

Introduction
This study investigates the differences in patient care across various organisational forms of general practitioners (GPs) in Upper Austria.

Methods
Data was collected from GPs across Upper Austria, examining patient demographics, prescription patterns, staff employment, services offered and the proximity of practices to hospitals. The variability in recording patient visit reasons was also analysed.

Results
Of the 30 participating GPs (Response Rate 5.1%), 17 worked in single practices, 7 in group practices, and 6 in PHC units. In our sample, single practices tend to prescribe more medications for chronic conditions. Group practices and PHC centres are more prevalent in areas with larger populations, offer online appointment bookings more frequently and employ more staff. The study also highlights variability in documenting patient visit reasons, emphasising the need for standardised documentation practices. The most common reasons for the patient to contact their GP, based on ICPC-2 categories, were general and non-specific, respiratory and locomotor problems, and the most common chronic diseases seen in the practice are cardiovascular, endocrine diseases and locomotor system problems. The most common therapeutic procedures were counselling and prescription of medication.

Conclusion
Our study, the first of its kind, reveals significant insights into the variability and adaptability of general medicine outpatient practices in Upper Austria, highlighting the need for improved diagnosis coding at the primary care level.
Factors Associated with Low Back Overuse Injuries in Sports Science Students – A Prospective Study
Authors: PODOBNIK Maja MIKŠA , ŠARABON Nejc , BILBAN Marjan , HADŽIĆ Vedran 
Published: January 2025

ABSTRACT

Background
Sports science students (SPS) are more likely to be affected by low back pain (LBP) compared to the young, physically active population. The aim of this prospective study was to evaluate potential risk factors for LBP in the population of SPS.

Methods
Before the beginning of the study the participants (n=54) performed initial physical performance testing and gave blood samples. Then they were followed up for 10 weeks. The observed outcome was LBP occurrence. The presence of the observed outcome was recorded using the Oslo Sports Trauma Research Centre Overuse Injury Questionnaire weekly. The association between LBP and potential explanatory factors - potential overtraining parameters (e.g. ferritin and iron levels, amount of sleep) and motor ability parameters (e.g. muscle strength, vertical jump) - was assessed using multiple binary logistic regression.

Results
During the 10 week prospective follow-up LBP was the most common problem affecting 13% of students. From the group of explanatory factors for LBP only two were included in the final model as statistically significant: low ferritin level (OR=8.70, p=0.008), and history of previous LBP (OR=8.69; p=0.006) made students more likely experience new LBP problems.

Conclusions
The SPS that are more at risk of experiencing LBP are those with a history of LBP and those with low ferritin level. Awareness should be raised among students about the importance of comprehensive LBP prevention (preventive exercise, preventive medical check up including blood test).
Optimizing Financial Data Analysis: A Comparative Study of Preprocessing Techniques for Regression Modeling of Apple Inc.’S Net Income and Stock Prices
Authors: Ungar Kevin , Oprean-Stan Camelia 
Published: January 2025

Abstract
This article presents a comprehensive methodology for processing financial datasets of Apple Inc., encompassing quarterly income and daily stock prices, spanning from March 31, 2009, to December 31, 2023. Leveraging 60 observations for quarterly income and 3774 observations for daily stock prices, sourced from Macrotrends and Yahoo Finance respectively, the study outlines five distinct datasets crafted through varied preprocessing techniques. Through detailed explanations of aggregation, interpolation (linear, polynomial, and cubic spline) and lagged variables methods, the study elucidates the steps taken to transform raw data into analytically rich datasets. Subsequently, the article delves into regression analysis, aiming to decipher which of the five data processing methods best suits capital market analysis, by employing both linear and polynomial regression models on each preprocessed dataset and evaluating their performance using a range of metrics, including cross-validation score, MSE, MAE, RMSE, R-squared, and Adjusted R-squared. The research findings reveal that linear interpolation with polynomial regression emerges as the top-performing method, boasting the lowest validation MSE and MAE values, alongside the highest R-squared and Adjusted R-squared values.
Wspomnienie o Ś.P Prof. dr hab. Konradzie Nowackim
Authors: Stelmasiak Jerzy 
Published: January 2025

Świętej Pamięci Profesor Konrad Nowacki był wybitnym przedstawicielem wrocławskiej szkoły administratywistów, jak i prawa ochrony środowiska. Jego bardzo bogaty dorobek naukowy obejmuje szeroko rozumianą problematykę prawa ochrony środowiska o charakterze komparatystycznym. Dotyczy to w szczególności badań porównawczych w zakresie prawa ochrony środowiska w Republice Federalnej Niemiec i Austrii. Dlatego też w 2009 r. z Jego inicjatywy Uniwersytet Wrocławski i Uniwersytet Techniczny w Cottbus utworzyły Polsko-Niemieckie Centrum Prawa Publicznego i Ochrony Środowiska. Ponadto w 2015 r. Profesor Konrad Nowacki otrzymał tytuł doktora honoris causa Uniwersytetu w Cottbus.