bluuebunny/crossref_metadata_2025_split huggingface dataset:
Students as partners in digital education: Exploring lecture capture in higher education through partnership between students and learning technologists
Authors: Luke Karl , Evans Geraint 
Published: November 2021

This case study reports on two student-staff partnership projects at Cardiff University that explored the student experience of using lecture capture technologies. We describe the background to these projects, how they were designed, and how students and staff worked together to gain insights into the student experience. The case study demonstrates that nuanced understandings regarding the way students use lecture recordings is required and argues that student-staff partnership is an effective way of achieving these understandings. Suggestions are offered regarding how educationists could further harness partnerships to explore the complex interplays between technology and student learning. This reflective account also explores our efforts in achieving meaningful partnership working, the challenges encountered, and highlights the benefits of partnerships between students and professional-services staff, specifically learning technologists.
Is NY's Supply-side Experiment Working? A Preliminary Analysis using County Unemployment Rates
Authors: Snarr Lynn B. , Snarr Hal , Friesner Dan 
Published: November 2021

The State of New York recently enacted business tax reforms. The first legislative act launched the START-UP NY program in 2014. It created tax free enterprise zones throughout the state to incentivize business incubation within, or relocation of existing firms to, the State of New York. In that same year, the state lowered its corporate tax rate state-wide from 7.1% to 6.5% in 2016. We use a difference-in-differences (DID) methodology, evaluated using county-level data, to empirically test whether New York’s recent business tax reforms significantly reduce unemployment, beyond what would exist in the absence of the reforms. We fail to find significant evidence that START-UP NY affects unemployment during the period studied, 2014-2017. We do, however, find evidence suggesting that New York lowering its corporate tax rates in 2016 is associated with a large reduction in unemployment (by approximately 90,000 jobs) in 2016 and a smaller reduction (by approximately 25,000 jobs) in 2017.
On the Distributional Outcomes of Policy-Induced Entrepreneurial Opportunities
Authors: Snarr Hal Wesley , Friesner Dan 
Published: November 2021

This analysis empirically evaluates the effectiveness of entrepreneurial policies using the number and distribution of firms as outcome variables. The analysis occurs within the context of a natural experiment: the START-UP NY program. Implemented in 2014, START-UP NY created enterprise development zones adjacent to publicly supported universities (i.e., SUNY and CUNY campuses) within the state. New business start-ups operating within these zones, and within a specific set of technology and health-related industries received tax incentives that substantially lowered tax rates for a 5-10 year period. In 2016, the State of New York substantially altered its corporate tax structure; a policy initiative affecting firms, business owners, and households in the state simultaneously, and may also induce entrepreneurship. The results suggest that START-UP NY had a positive effect on the growth of New York's micro and small-sized firms operating in professional, scientific, and technical industries. START-UP NY also negatively affected micro-sized manufacturing firms, while positively affecting small manufacturing firms. The latter finding suggests that START-UP NY is effective in incubating micro-sized manufacturing firms that eventually grow into small manufacturing firms.
Prevalence of Allergic Diseases in Children Vaccinated Against Tuberculosis and Hepatitis B in the Early Neonatal Period: Literature Review
Authors: Fedoseenko Marina V. , Petrova Veronika A. , Namazova-Baranova Leyla S. 
Published: November 2021

Background. T-cell response is shifted towards Th2-type predominance in newborns. This makes them particularly vulnerable to exposure of various external pathogens, development of severe infections, moreover, it is also a risk factor for allergic diseases development. Various methods of switching the immune response to Th1-type are currently under research, and one of them is vaccination.Objective. The aim of the study is to provide data on the prevalence of allergic pathology among children vaccinated against tuberculosis and hepatitis B, as well as the effect of vaccines on immune response type.Results. Data on both increase and decrease in the prevalence of atopic conditions in children vaccinated with BCG and against hepatitis B were analyzed, thus, most of them cannot be considered reliable. The results of several large studies do not reveal any correlation between vaccination and the presence of allergic disease in children. There is data that BCG and hepatitis B vaccines shift the immune response towards Th1-type activation.Conclusion. Vaccination in the early neonatal period may affect switching of the immune response towards Th1-type. That, in turn, can affect the prevalence of allergic pathology in vaccinated children. However, the data available for now is not sufficient to reliably estimate the possible effect of vaccination on atopic conditions manifestation in the future.
Magna Cosmogony
Authors: Serpa Nilo , Cathcart Richard Brook 
Published: November 2021

<p><strong>Abstract:</strong> This article aims to show that science and faith have always walked closer than is usually thought, and that they can even coexist harmoniously in the same individual. It also seeks to show the sterility of the debate that puts both in direct confrontation, evidencing the often prejudiced and disdainful position of current science towards faith as a characteristic of the human condition, whether or not it is associated with a religion. In a broader approach, it discusses currently existing beliefs about the existence of intelligent life outside the Earth in contrast to the possibilities that science offers in our actual state of technological development. In addition, the work intends to convey the perception that it would be much more constructive to accept faith as a natural manifestation of consciousness that recognizes the limits of knowledge, rather than rejecting it through scientific arguments that, being faith, is manifestly inapplicable.</p><p><strong>Key-words:</strong><strong> </strong>science, faith, cosmogony, cosmology.</p><p>================================================================ </p><p><strong>Resumo:</strong> Este artigo tem como objetivo mostrar que ciência e fé sempre estiveram mais próximas do que normalmente se pensa, e que podem até coexistir harmoniosamente no mesmo indivíduo. Também busca mostrar a esterilidade do debate que as coloca em confronto direto, evidenciando a posição muitas vezes preconceituosa e desdenhosa da ciência atual em relação à fé como característica da condição humana, associada ou não a uma religião. Em uma abordagem mais ampla, discute-se as crenças atualmente existentes sobre a existência de vida inteligente fora da Terra em contraste com as possibilidades que a ciência oferece em nosso atual estado de desenvolvimento tecnológico. Além disso, o trabalho pretende transmitir a percepção de que seria muito mais construtivo aceitar a fé como manifestação natural da consciência que reconhece os limites do conhecimento, do que rejeitá-la por meio de argumentos científicos que, para ela, sendo fé, não se aplicam.</p><p><strong>Palavras-chave:</strong> ciência, fé, cosmogonia, cosmologia.</p>
Assessing the Contribution of Vision 2020 Umurenge Programme on Poverty Reduction in Kigabiro Sector, Rwanda
Authors: Pascal Rwakibibi 
Published: November 2021

The study aimed at assessing the contribution of VUP in poverty reduction especially in Kigabiro sector. This study has general objective which is to assess the contribution of Vision 2020 Umurenge programme on poverty reduction supported by three specific objectives which are to assess the contribution of public works on poverty reduction, to determine the contribution of financial services on poverty reduction, and also to evaluate the contribution of direct support services on poverty reduction especially in Kigabiro sector located in Rwamagana district, Eastern province. Internationally, poverty can describe different things in different part of the world to different people, but it can be defined as when people are not able to afford basic needs. USA has come a long way in addressing the problem, but progress seems to have slowed despite the recent years of economic recovery. In Africa, hundred millions of people in the poorer countries are worries only with survival and elementary needs and average poverty rate for sub-Saharan Africa stands at about 41 percent, and of the world’s 28 poorest countries, 27 are in sub-Saharan Africa all with a poverty rate above 30 percent. Referring to Rwanda, because may people in Rwanda live in rural area, they also live-in poverty line which is so hard for GoR to answer each Rwandan’s problem but poverty alleviation program has been established in order to reduce gap of lower bad living condition of Rwandans due to genocide took place in 1994 against Tutsi. In 1994 the poverty rate was 78%, in year of 2000 poverty rate was 60.4%, 2011 poverty rate was 44.9%. 2014 poverty rate was 39.1% and in 2020 poverty rate was 20%. So, even if the poverty rate mentioned above are decreasing, poverty rate of 20% in 2020 is still high meaning that many people are in the poverty which is the main problem in this studies.
In dogs with uncomplicated corneal ulcers, do antibacterial eye drops reduce the risk of infection?
Authors: Johnson Sery , Gordon-Evans Wanda 
Published: November 2021

PICO question
In dogs with uncomplicated corneal ulcers does treatment with prophylactic antibacterial eye drops reduce the risk of secondary infection when compared to no treatment with prophylactic antibacterial eye drops?

Clinical bottom line
Category of research question
Treatment
The number and type of study designs reviewed
Zero
Strength of evidence
Zero
Outcomes reported
None
Conclusion
There were no published papers found to address the PICO

How to apply this evidence in practice
The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
Pharmacoeconomic Study on the Application of Magnetic Resonance Imaging with Gadoxetic Acid in Addition to Contrast-Enhanced Computed Tomography in Diagnosis of Hepatocellular Carcinoma
Authors: Kаrmаzаnovsky G. G. , Volobueva A. A. 
Published: November 2021

Objective: to evaluate pharmacoeconomic advantages of the application of magnetic resonance imaging (MRI) with hepatobiliary-specific contrast agent – gadoxetic acid in addition to contrast-enhanced computed tomography (CT) in the diagnosis of hepatocellular carcinoma (HCC).Material and methods. We performed the modeling and obtained the results of the pharmacoeconomic study: effectiveness analysis, cost analysis, and cost-effectiveness analysis. The cost analysis included only direct medical costs (the cost of contrast-enhanced CT, gadolinium-based contrast agent (GBCA) for MRI, and therapy per a patient with verified HCC diagnosis after diagnostic procedures). The financing was performed from the Compulsary Health Insurance Fund. The calculations were made per 1 patient.Results. The effectiveness analysis showed that the diagnostic scheme CT + MRI with gadoxetic acid was the most effective complex for the diagnosis of HCC because its application provided 50% of patients with 5-year overall survival (4.8 years), which was significantly higher than in patients who were diagnosed HCC with CT + MRI with extracellular GBCA (2.3 years) or CT (3.7 years). The cost-effectiveness analysis showed that the diagnostic scheme with gadoxetic acid was dominant because each disability-adjusted life year required fewer costs (14 862 rubles) in comparison with CT + MRI with extracellular GBCA (25 293 rubles) or CT (46 540 rubles). According to the results of the incremental cost-effectiveness ratio analysis, the application of the diagnostic complex with gadoxetic acid was characterized by the lowest rate of additional costs per 1 disability-adjusted life year.Conclusion. The pharmacoeconomic study showed that the application of MRI with a hepatospecific contrasting agent – gadoxetic acid in addition to contrast-enhanced CT was an effective and economically beneficial method of early HCC diagnosis.
Comparison of the Main Staging Systems for Assessing the Severity of Lung Injury in Patients with COVID-19 and Evaluation of Their Predictive Value
Authors: Kudryavtsev Y. S. , Beregov M. M. , Berdalin A. B. , Lelyuk V. G. 
Published: November 2021

Objective: to compare the results of staging the severity of viral pneumonia in patients with COVID-19 based on the results of chest computed tomography (CT) using the empirical visual scale CT 0–4 and chest CT severity score (CT-SS) point scale, as well as to assess their prognostic value.Material and methods. Chest CT scans and anamnestic data in patients hospitalized to a non-specialized center repurposed for the treatment of new coronavirus infection, were analyzed. Chest CT analysis was performed by two radiologists using CT 0–4 and CT-SS scales.Results. The time course of changes in the severity of lung parenchymal lesions, by using both scales, was found to be similar: the maximum magnitude of lung tissue changes was recorded on day 5 of the disease. In cases of death, there was a significantly more extensive lung parenchymal involvement at admission to the center than in recovered patients, which was also true for both CT data assessment systems. Bothscales demonstrated comparable diagnostic and prognostic value: there were no statistically significant differences in sensitivity, specificity, and predictive value of a fatal outcome. Both the CT 0–4 scales and the CT-SS are based on the estimation of the volume of the affected lung tissue, but when the CT 0–4 scale was employed, additional criteria were used in some cases: the presence of hydrothorax and the determination of the maximum score for the most affected lung. Not all patients with a pronounced CT picture of viral pneumonia had a fatal outcome, which may indicate the presence of other factors that increase its risk.Conclusion. Both CT 0–4 and CT-SS scales have similar predictive values. The greater severity of parenchymal damage assessed by these CT scales was associated with the higher mortality rate.
Fracture Nonunion of the Clavicle After Surgical Reduction in a 13-Year-Old Girl
Authors: Davat Marie , Steiger Christina N. , Tabard-Fougere Anne , Dayer Romain , Ceroni Dimitri 
Published: November 2021

Case:
Although congenital nonunion of the clavicle is a well-known pathology in children, posttraumatic nonunion is a rare entity. Nonunion after open reduction and internal fixation of a clavicle fracture is exceptional in the pediatric population. We report on a patient presenting posttraumatic pseudarthrosis of the clavicle after surgical treatment. Pseudarthrosis was resected, and the defect was bridged with an iliac crest autograft, supplemented with bone morphogenetic protein, and fixed with an elastic stable intramedullary nail.

Conclusion:
This procedure offered enough stability for achieving fracture consolidation and is a safe alternative to plating in clavicle nonunion.
A Hybrid Technique to Treat Inguinal Wound Infection after Arterial Surgery with Lateral Femoral Bypass and Intra-Incisional Negative Pressure Wound Therapy
Authors: Wu Yi-Fan , Zhang Dong , Yu Ai-Xi , Qi Baiwen , Jian Chao 
Published: November 2021

Abstract
Background: Patients with the inguinal wound infection after arterial surgery remains clinical challenge. Sustaining lymphatic leakage have been shown as a common and potentially serious complication. However, it remains clinical challenge for surgery to deal with this tough problem. Methods: This study describes a hybrid technique of using radical debridement, lateral femoral bypass (LFB) and intra-incisional negative pressure wound therapy (iNPWT) for single-staged treatment of complex inguinal wound infection after arterial surgery (IWI-AS).Results: Between January 2017 and June 2021, 5 IWI-AS cases treated with this new method were identified. Of the patients, 3 were males and 2 were females. The average age was 49.4 years (range, 33 to 77 years). 4 cases suffered emergent operations due to the sudden bleedings. after vascular bypass reconstructions and an average of 2.2 (range:1-3) iNWPT, all cases achieved wound healing at an average duration of 4.6 weeks (range: 3-6weeks). Moreover, all cases showed no bacterial growth and grafts patency as indicated by doppler ultrasound or CT angiography postoperatively. One case did not receive bypass imaging evaluation at postoperative 12 months. Weakness of quadriceps femoris was observed in one case. Conclusion: single-staged therapy of LFB and iNPWT hybridization is a technically handy and effective method for treatment of inguinal wound infection after arterial surgery.
Influence of genome methylation of fig tree accessions on the natural nematode and rust incidence
Authors: Rodrigues Maria Gabriela Fontanetti , Firmino Ana Carolina , Valentim Juliano Jorge , Pavan Bruno Ettore , Ferreira Antonio Flávio Arruda , Monteiro Laís Naiara Honorato , Martins Maria Eugênia Silva , Ramos Ester Silveira , de Soutello Ricardo Velludo Gomes 
Published: November 2021

Abstract
Brazil is the largest fig producer in South America, but the Brazilian commercial fig tree cultivation is based on the planting of a single cultivar, ‘Roxo-de-Valinhos’, resulting in serious problems related to diseases. Since there are epigenetic variations in the plant-pathogen interaction, mainly through gene regulation, the aim of this study was to carry out the in vivo characterization of fig accessions through the analysis of the natural root-knot nematode and leaf rust incidence correlated to its epigenomic profile, in order to support conservation works and genetic improvement. Regarding the analysis of the presence of nematodes, it was observed that all plants were attacked by this pathogen, and the identification of Meloidogyne incognita as the root-knot nematode species was confirmed. However, the rust incidence and the global genomic methylation content where statistical different between evaluated accessions. The joint analysis of data showed that methylation and the leaf rust incidence, when observed in the same phenological phase of plants, are correlated, presenting evidences of the same factorial pressure loads in genotypes, with the premise of similar behavior in these genotypes. Biotic factors are also responsible for changes in the DNA methylation of plants, demonstrating a positive role in promoting plant defense.
BATF Inhibits Cell Proliferation and Migration via PI3K/AKT/mTOR Pathway in Clear Cell Renal Cell Carcinoma
Authors: Li Ming , Jin Jun , Yang Zhihui , Chen Xiaoli , Chen Yongzhong , Liu Zewen , zhang Hong , Zhao Liqin , Zhou Fuxiang 
Published: November 2021

Abstract
Background
Previous studies reported that BATF played an important role in the progression of various cancers, but no report had been found on clear cell renal cell carcinoma(ccRCC). So we investigated the effects of BATF on the progression of ccRCC.
Methods
In this study, using TCGA-KIRC database from the Cancer Genome Atlas to analyze the differential genes of BATF in ccRCC ; using immunohistochemistry to detect BATF expression in 75 ccRCC tumorous and 28 nontumorous tissues, and investigate its relationship with clinicopathological parameters. Moreover, we constructed the cell lines of BATF overexpression and knockout in Caki-1and 786-0 ccRCC cell lines and confirmed by western blot. CCK8 assay was used to evaluated the cell viability and using EdU staining to detect cell proliferation; using Transwell experiment to investigate the affection of BATF in ccRCC cell migration. Westernblot was used to detect the phosphorylation of PI3K/AKT/mTOR.
Results
These results revealed that BATF expression in ccRCC tumorous was significantly higher compared with that in adjacent nontumorous tissues and was significantly correlated with T stage, Fuhrman grade, Tumor necrosis and status. In addiditon, BATF overexpression significantly inhibited the viability, proliferation and migration of the two cell lines. More importantly, using westernblot showed that silencing BATF significantly increased the level of phosphorylated AKT, PI3K and mTOR, while BATF overexpression decreased phosphorylation that involved in the PI3K/Akt/mTOR signaling pathway.
Conclusions
Our findings demonstrate that BATF plays an important role in the progression of ccRCC and it may act as an tumor supressor gene to inhibit the progression of ccRCC through regulating the PI3K/Akt/mTOR signaling pathway.
Knowledge, Attitudes, and Practices Towards Avian Influenza Among Students of Two Public Universities of Surabaya, East Java, Indonesia
Authors: Rehman Saifur , Rantam Fedik , Khan Muhammad , Shehzad Aamir , Effendi Mustofa 
Published: November 2021

Abstract
Background and objectives:
Avian influenza is a highly contagious disease that causes respiratory failure and has significant public health implications due to its zoonotic potential. Humans are frequently affected after coming into contact with infected birds, body fluid droplets such as those produced during defeathering operations, or other contaminated objects. This study aimed to appraise the students' knowledge, attitudes, and practices (KAPs) related to avian influenza in Surabaya, East Java, Indonesia.
Methods
Among the students, 300 were interviewed to collect their knowledge about avian influenza and its zoonotic importance. The study population comprised students studying at two public universities having an age range of <20-50 years.
Results
Of the 300 respondents, 97.7% and 92.3 % were aware of the term avian influenza contagious infection and its pathogenicity related to zoonotic potential. Correlations show that the student's educational status was positively associated with knowledge of animal-to-animal transmission of avian influenza (p < 0.039). More than 80-90% of participants had knowledge that infected poultry and birds act as a potential source of avian influenza infection. More than 75% of the participants suspect poultry workers, butchers and veterinarians were at high risk of avian influenza infection. Fifty-seven percent of the students were not consulted to the doctor whenever they feel influenza-like symptoms. Washing of hands before and after eating a meal and covering of nose during coughing and sneezing were common. Our study results delineated the association of contagious infection of avian influenza transmission to poultry workers after contact with infected birds (p < 0.004).
Conclusion
Our study indicated that the knowledge, attitude, and practices of avian among the students were high, which might provide scientific support to the Indonesian government in developing strategies and public health campaigns among the general population to reduce the disease incidence.