bluuebunny/crossref_metadata_2025_split huggingface dataset:
EVASÃO EM CURSOS DE LICENCIATURA DE CIÊNCIAS EXATAS E NATURAIS
Authors: Sousa Waleska Dayse Dias , Costa Carla Regina , Souza Daniele Cristina de , Ornellas Janaina Faria de , Lemes Leandro Cruvinel , Moreira Marcos Dionizio , Cintra Mariângela Torreglosa Ruiz , Aléssio Osmar , Buranello Patrícia Andressa de Almeida , Silva Ricardo Souza da , Melo Alan Lopes , Alves Moyses De Oliveira Pereira , Cruz Ana Cristina Thiersch , Prata Bianca Oliveira Pontes 
Published: June 2021

Um grupo multidisciplinar de profissionais da Universidade Federal do Triângulo Mineiro realizou estudo com o objetivo de compreender os índices de evasão dos cursos de graduação do Instituto de Ciências Exatas, Naturais e Educação e de apresentar proposições. Foram utilizados os seguintes procedimentos teórico-metodológicos: revisão de literatura sobre o tema evasão na Educação Superior, levantamento de dados no sistema acadêmico da instituição e nos setores que registram a vida escolar dos estudantes e questionários. O estudo concluiu que o fenômeno da evasão é complexo, multifacetado, social e historicamente referendado, pois envolve desde questões relacionadas às condições objetivas de permanência na universidade, como questões financeiras, tempo, saúde, problemas familiares, até condições subjetivas como dificuldades de aprendizagem, dificuldades de adaptação à proposta pedagógica e à cultura acadêmica, falta de identificação com o curso e dúvidas quanto à inserção no mundo do trabalho após a formação. O estudo propôs o fortalecimento de ações institucionais que impactem na permanência e no sucesso acadêmico, além da implementação de um projeto de tutoria. Também indicou a necessidade de definir uma política institucional de combate à evasão com responsabilidades dos diferentes setores e profissionais da universidade, recursos e formas de acompanhamento articulado.
THE BACTERIA AND PARASITE PATTERNS IN FLIES DO NOT ASSOCIATE WITH THE PREVALENCE OF FLY VECTOR-BORNE DISEASES AT THE DAIRY FARM
Authors: Zam Riza Indira Fadillah Zam , Sulistyaningsih Erma , Marchianti Ancah Caesarina Novi 
Published: June 2021

The fly is the vector of several intestinal diseases. It can transmit pathogenic agents, including bacteria such as Salmonella, Shigella, Escherichia coli, Staphylococcus, as well as parasites such as Entamoeba histolytica, Balantidium coli, and Giardia lamblia. The dairy farm is one of the sites where the flies are commonly found. This study analyzed the association of the bacteria and parasites pattern in flies and the prevalence of fly vector-borne diseases at the dairy farm. The fly samples were collected at the Rembangan Dairy Farm, and the bacteria and parasite were identified at the Laboratory of Microbiology and Parasitology, Faculty of Medicine, University of Jember. The prevalence data of fly vector-borne diseases were collected from the Public Health Centers around the study site as secondary data. Bacteria identification using selective media found only E. coli, but no parasite was observed in the samples. We found diarrhea, typhoid, and dysentery as fly vector-borne diseases. Statistical analysis using chi-square resulted in p=0.072, meaning no significant association of the bacteria and parasites pattern in flies and the prevalence of fly vector-borne diseases at the dairy farm. The use of secondary data for disease prevalence could be a limitation of the study. Further study by directly examines the samples from fly vector-borne diseases is needed to draw a definite conclusion.
Sintesis dan Uji Aktivitas Antibakteri Senyawa N-fenil-4-klorobenzamida
Authors: Wisnu Elok Dea Orens Ubung , Sary Indah Purnama , Pratoko Dwi Koko 
Published: June 2021

N-phenylbenzamide is benzamide derivatives, which is potential as an antibacterial agent. N-phenyl-4-chlorobenzamide is N-phenylbenzamide derivative that substitued by chloro to the para position and it was expected to enhance the antibacterial activity. N-phenyl-4-chlorobenzamide was synthesized by reacting 1,3-diphenyilthiourea and 4-chlorobenzoil chloride. This compound has been purified and provided 53% of product with crystal shape, white color, and melting point of 195-197 oC. The purification of this compound was confirmed by TLC and the structure was identified by 1H-NMR, 13C-NMR, and FTIR spectroscopy. This compound was tested for its activity against gram positive bacteria Staphylococcus aureus and gram negative bacteria Pseudomonas aeruginosa, evaluated by well diffusion method and the result showed no activity against both Staphylococcus aureus and Pseudomonas aeruginosa.

Keywords: N-phenyl-4-chlorobenzamide, synthesis, antibacterial activity
Pengaruh Propilen Glikol dalam Patch Dispersi Padat Ketoprofen terhadap Karakteristik Fisika Kimia dan Laju Penetrasinya
Authors: Ameliana Lidya , Dwiputri Haris Raudhatuzakinah , Nurahmanto Dwi 
Published: June 2021

Ketoprofen is a non steroid anti-inflammatory drug (NSAID) used as analgesic and anti-inflammation. This research had been done by ketoprofen patch preparation and evaluations aiming to enhance its penetration through the skin using propylene glycol as penetration enhancer. Evaluations included homogenity testing and FTIR for ketoprofen solid dispersion and organoleptic, weight uniformity, thickness, folding endurance, surface pH, moisture content, and penetration rate assay of ketoprofen patch. Penetration rate was determined by paddle type dissolution and the sample was analyzed by spectrophotometry UV-Vis. The value of moisture content and penetration rate were analyzed by One Way ANOVA with confidence level of 95 %. The value of moisture contents were F0 1.17 ± 0.0551 %; F1 1.27 ± 0.0208 %; F2 1.33 ± 0.08 %; and F3 1.43 ± 0.0208 %. The penetration rates of ketoprofen were F0 0.5258 ± 0.0191 µg/cm2.minute; F1 0.6935 ± 0.0613 µg/cm2.minute; F1 0.6935 ± 0.0613 µg/cm2.minute; and F3 1.1260 ± 0.0850 µg/cm2.minute. It can be concluded that the formula with propylene glycol 150 mg/patch can deliver the best penetration rate and moisture content that were fullfill the requirements.

Keywords: ketoprofen, patch, propilen glikol, penetratio enhancer, solid dispersion
Kadar Puncak (Cmax), Waktu Puncak (Tmax), Waktu Paruh (T½) dan Bersihan Teobromin pada Sukarelawan Sehat setelah Pemberian Dark Chocolate Bar Per Oral
Authors: Suwandi Nyoman Defriyana , Abrori Cholis , Hasan Muhammad 
Published: June 2021

Dark chocolate contains two derivates of metilxantin, I.e. caffeine (1,3,7-trimetilxantin) and theobromine (3,7 dimetilxantin). Theobromine can be found in plasma. Theobromine concentration in plasma determined not only by drug dosage but also by pharmacokinetic parameters. This research aimed to determine pharmacokinetic parameters by using HPLC (High Performace Liquid Chromatography) method. This study used Quasi Experimental Design by using 16 plasma samples collected at the 0, 1.5, 3, 6, 10, 24 hours. The pharmacokinetic parameter calculations were obtained from the polynomial curve and linear curve of drug concentration in plasma by time. The maximum concentration (Cmax) theobromine on plasma after consumption of dark chocolate bar per oral was 4.173 mg/L. The maximum time (Tmax) was at the 2.501 hours. The half time (t½) theobromine was 4.880 hours. Theobromine clearance in plasma was 14.2 ml/kg/hour. The study has reported pharmacokinetic parameters of theobromine in plasma after eating dark chocolate bars orally.

Keywords: Chocolate, half-time, maximum concentration, maximum time, theobromine
Hubungan Indeks Kepuasan Pasien tentang Mutu Pelayanan Dimensi Kehandalan dengan Minat Berobat Kembali di RSD Kalisat Kabupaten Jember
Authors: Amalia Davina , Rachmawati Dwita Aryadina , Hairrudin Hairrudin 
Published: June 2021

RSD Kalisat is one of the hospital that is very concern with the quality of health services. The reliability of service quality is often perceived as the most important dimension for the customer. Quality of service is very influential on patient satisfaction. If the health care provided is good, then the patient will be satisfied and the possibility to reuse services in health care-related agencies will increase. The purpose of this study was to determine the correlation between patient satisfaction index in the reliability of service quality with utility at RSD Kalisat. This study used cross sectional design with total sample of 84 respondents. The instrument used was RSD Kalisat profile and questionnaire to determine patient satisfaction index in the reliability of service quality and statement for utility. The results of statistical test by Spearman's Rho showed a significance value (p=0.021) and the correlation coefficient (r =0.252). Thus, it can be concluded that there was a significant correlation between patient satisfaction index in the reliability of service quality with utility at RSD Kalisat Jember with a weak correlation.

Keywords: index satisfaction, reliability, service quality, utility
Deteksi Protein 270 kDa Plasmodium falciparum Isolat Malang pada Membran Eritrosit Penderita Malaria dengan Komplikasi
Authors: Indiastari Dewi , Winarsih Sri , Fitri Loeki Enggar 
Published: June 2021

Erythrocyte which is infected by Plasmodium falciparum will have various changes on its architecture, affinity, and biomolecular. Beside that, the infected erythrocyte also forms a knob at its surface. This knob are contained with various parasite proteins, one of them is Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP-1). Our previous study had been identified a protein with molecular weight 270 kDa at P. falciparum infected erythrocyte from Malang isolate that was playing a role in cytoadherence process. The aim of this study was to detect the possibility of 270 kDa protein expression at complicated malaria falciparum patient erythrocyte membrane. The method that used was immunocytochemistry with polyclonal antibody to 270 kDa protein. The results showed that two (2) erythrocyte samples from healthy people as control had negative reaction, and so did with five (5) erythrocyte samples of uncomplicated malaria patient, but there was positive reaction that shown at two (2) samples of complicated malaria patient erythrocyte. It can be concluded from the results that 270 kDa membrane protein of P. falciparum infected erythrocyte in complicated malaria patient might be a PfEMP-1. This protein can be detected by immunocytochemistry method using polyclonal antibody and can be used for the candidate of complicated malaria diagnostic

Keywords: Plasmodium falciparum, 270 kDA protein, immunocytochemistry, polyclonal antibody
Hubungan Jenjang Pendidikan terhadap Perilaku Menjaga Kesehatan Gigi dan Mulut Anak Tunagrahita di SLB Kota Sidoarjo
Authors: Julia Dianita Rahmah , Endah Yani Ristya Widi , Budirahardjo Roedy 
Published: June 2021

Intellectual disability is a child who suffers from intellectual ability below average and tends to have retardation in intelligence, physical, emotional, and social. They are not independent enough in keeping their own health especially oral hygiene, it can affect their oral health behavior. Education that is one of external factors influences health behavior. Education and knowledge influence each other so that people are expected to have high education in order to be knowledgeable especially in terms of maintaining health. The purpose of this study was to analyze the correlation between education level and oral health behavior of children suffering from intellectual disability. This research was an observational analytic research with cross sectional approach. The subjects of this study were a number of children of SDLB, SMPLB and SMALB in SLB Sidoarjo, with total sampling as many as 115 students. The subjects were asked to fill out a questionnaire of knowledge and attitude how to brush teeth and performed the action as well. The collected data were analyzed by using spearman correlation test. The result of this research showed that correlation coefficient for education level with knowledge, attitude and behavior was > 0,05, so there was no relation between those variables. Meanwhile, the result of correlation coefficient of education with action was < 0.05, so there was correlation between those two. The conclusion of this research is there is no correlation between the level of education and oral health behavior of intellectual disability children in SLB Sidoarjo.
Keywords: Mental retarded, dental health behavior, education level
Hubungan Pencapaian Tugas Perkembangan Keluarga Tahap VIII (Aging Family) dengan Perilaku Pemenuhan Kebutuhan Spiritual: Sholat Pada Lansia
Authors: Kharisma Fajar , Rasni Hanny , Purwandari Retno 
Published: June 2021

Not all religious activity in the elderly can be implemented well, so there are limitations due to physicalconditions that are not strong anymore. Therefore, the family is expected to motivate and facilitate theelderly to meet the spiritual needs so as to increase devotion elderly against God Almighty. This researchaims to analyze the relationship between eight stage (aging family) of family development task with thebehavior of spiritual fulfillment: sholat on the elderly in the Sumbersari village, Jember regency. Thisresearch was observasional analytic using cross sectional study. Data collection was conducted inDecember 2017 at 82 elderly by using cluster random sampling. The research result showed that Familydevelopment task is reached (56.1%) and the average behavior of spiritual fulfillment: prayers 69.11.Statistical test used the Spearman rank that indicated p-value>alpha with 0.359>0.05 which meant therewas no relation between eight stage (aging family) of family development task with the behavior ofspiritual fulfillment: prayers on the elderly in the Sumbersari village, Jember regency. Family support isvery important for the elderly, especially in carrying out the task the development of families with elderly.However, the research result obtained family development task not have correlation on the behavior ofspiritual fulfillment: sholat in elderly, it can be affected by other factors such as the elderly haveconfidence and awareness in carrying out religion activities such as sholat for the provision in the afterlife.
Keywords: aging family, sholat, elderly
Optimasi Zink Oksida Dan Asam Malat dalam Krim Tabir Surya Kombinasi Avobenzone dan Octyl Methoxycinnamate dengan Desain Faktorial
Authors: Rosyidi Viddy Agustian , Ummah Lisanul , Kristiningrum Nia 
Published: June 2021

Ultraviolet rays (UV) has an adverse effect on the skin, which is epidermis damage. One way to prevent the adverse effects of UV rays on the skin can be done by using sunscreen. The sunscreen mechanism of action was divided into chemical absorber and physical blocker. Chemical absorber will be degradated when exposed to UV rays, while ZnO as physical blocker can increase pH value of the sunscreen. The effectiveness of sunscreen was affected by pH value, so malic acid was added into the sunscreen formula to decrease pH value. This study was aimed to determine the optimum composition of ZnO and malic acid on pH, viscosity, SPF, transmission of erythema and transmission of pigmentation using factorial design method. 0,5% ZnO was set as the lowest level and 3% ZnO was set as the highest level; 0,5% malic acid was set as the lowest level and 0,8% malic acid was set as the highest level. Selected optimum formula was 0,5% ZnO and 0,8% malic acid with the predicted SPF value of 21,242; TE of 0,000; TP of 0,000; pH of 4,820; and viscosity of 80,333 dPa.s

Keywords: sunscreen, Zinc Oxide, malic acid, Sun Protector Factor
La financiación de las universidades hispanas durante el período medieval (siglos XIII-XV)
Authors: Guijarro González Susana 
Published: June 2021

Este artículo analiza los modelos de financiación de las universidades medievales de la Corona de Castilla y de la Corona de Aragón durante su primera andadura en los siglos medievales. La comparación entre dichos modelos revela diferencias y similitudes. Las diferencias observadas están relacionadas con el papel desempeñado por la monarquía, el pontificado, los obispos junto con sus cabildos catedralicios y los gobiernos municipales en su origen y evolución durante la Baja Edad Media. Las similitudes atañen a la administración y tipología de las fuentes de ingreso que demostraron ser insuficientes e inestables. La debilidad económica de estas universidades medievales hizo necesario el recurso continuo a la protección pontificia. Por otra parte, el compromiso de las ciudades y las oligarquías urbanas que las gobernaban para con esta nueva institución educativa no fue siempre igual de firme y efectivo.
Acute Postoperative Pulmonary Embolism Detected at Home by a Patient's Personal Activity Monitor
Authors: Drynan David , Leroux Timothy S. , Zywiel Michael G. 
Published: June 2021

Case:
The increase in smart technology and integration into health care is inevitable. We present a case of a smart wristwatch prompting a patient readmission to the emergency department for postoperative pulmonary embolism investigation and management. This prompted the assessment for community-based smart technology use and integration to the postoperative monitoring and the associated issues.

Conclusion:
Community-based smart technology is here to stay and is developing at a staggering rate, specifically with the cross-over to health monitoring. Constant patient monitoring and alerts are advantages, with smart technology and medical attention in this case. Surrounding issues of the technology must be considered with implementation.
Superior Patellar Dislocation Reduced by Intra-articular Injection
Authors: Berry Chirag A. , Summers Melissa A. , Reddy Krishna I.A. 
Published: June 2021

Case:
A 53-year-old woman presented with a locked knee after an atraumatic hyperextension episode. Imaging showed an anterior tilt of the patella hinging over the superior trochlear margin, consistent with a superior patellar dislocation. The patella spontaneously reduced on an intra-articular injection with 15 mL of lidocaine in normal saline, after which she was able to actively range her knee.

Conclusion:
Superior patellar dislocations are rare and usually result from a sudden forced contraction of the quadriceps, trapping the patella over superior trochlear osteophytes. Reduction is possible through an intra-articular local anesthetic injection, without manipulation of the patella.
Single Cell scale RNA-seq Analysis Protocol to analyze Smart-3SEQ data from RAGP neurons of pig heart
Authors: Kuttippurathu Lakshmi , Moss Alison , Vadigepalli Rajanikanth 
Published: June 2021

Abstract
The present protocol describes transcriptome mapping, data normalization and analysis pipeline with detailed steps for each of these aspects for single cell/ low input RNASeq data from Right Atrial Ganglionated Plexus (RAGP) of pig heart. The protocol with minor modifications can be adapted for low input samples with short reads or samples with low quality input RNA. Single cell samples acquired using Laser Capture Microdissection (LCM) were processed for RNA-Seq library preparation using Smart-3SEQ technique (Foley et al 2019). The data analysis workflow consists of (a) pre-processing- data trimming, read alignment and feature count and (b) downstream analysis- annotation, batch correction, filtering and normalization. The entire protocol is performed using freely available packages. Most of them are available within the R framework.
Utilization of Refuse Derived Fuel for Energy Recovery Processes: Prediction of Environmental Emissions and Thermal Behaviour in Combustion Processes
Authors: Singhal Deepak Kumar , Gupta Divya , Garg Anurag 
Published: June 2021

Abstract
In the present study, the environmental emissions from co-combustion of refuse derived fuel (RDF) in cement plants and coal-fired power plants are predicted using mass and energy flow modeling. Mumbai was considered as study area and RDF characteristics were assessed using MSW composition in Mumbai. The modeling results suggested that with increase in RDF share in fuel mixture, significant reduction in environmental parameters such as winter smog, global warming and acidification potentials could be achieved, though the electricity and heat generation were reduced. This problem can be overcome by improving the quality of RDF. Moreover, thermal gravimetric analysis (TGA) of individual RDF components (compostable organic matter, paper, wood and plastic) was carried out in oxidative environment to understand their thermal stability. Average activation energies for plastic, wood and compostable organics (98.6–183 kJ/mol) were comparable to those reported for coal. The results suggest that coal and RDF co-combustion should not affect the combustion profile. Moreover, high plastic content in RDF can assist in control of combustion process and also can enhance its calorific value.
A Simulation-Optimization System to Assess Dam Removal With a Focus on Environmental Degradations at Downstream
Authors: Sedighkia Mahdi , Abdoli Asghar 
Published: June 2021

Abstract
The present study proposes and evaluates an integrated framework to assess dam removal in which downstream river habitats and reservoir operation were simulated in three different statuses including conventional reservoir operation optimization, optimal release considering environmental aspects in the structure of the optimization model and natural flow. Fuzzy physical habitat simulation was used to assess physical habitats. Moreover, ANFIS based model was utilized to simulate thermal tension and dissolved oxygen tension at downstream habitats. Particle swarm optimization was applied in the optimization models. Results of the optimization models and habitat suitability in the natural flow were compared by applying different measurement indices including reliability index, vulnerability index, The Nash–Sutcliffe model efficiency coefficient (NSE) and root mean square error (RMSE). Based on the results in the case study, reliability of water supply might be reduced in the optimal release for environment and demand. Furthermore, optimal release for environment is not able to protect downstream aquatics habitats properly. Thus, if protecting downstream habitats is aimed, dam removal might be logic in the case study. The main limitation of the proposed method is high computational complexities.
A Survey on Big Data Research in Fighting COVID-19: Contributions and Techniques
Authors: Riswantini Dianadewi , Nugraheni Ekasari , Munandar Devi , Arisal Andria , Suwarningsih Wiwin 
Published: June 2021

Abstract
COVID-19 has induced many problems in various sectors of life for humanity around the world. After one year of pandemic, many studies have been carried out in exposing various technology innovations and applications to combat the coronavirus that has killed more people than most. The pandemic has accelerated the use of Big Data technology to mitigate the threats of COVID-19. This survey aims to explore the Big Data research for COVID-19. We collected and analyzed the relevant academic articles to identify how Big Data technology can cover the challenges faced in overcoming the pandemic. In determining the research areas addressed by the past studies, we highlight the technology contributions to five major areas of healthcare, social life, government policy, business and management, and the environment. We discuss how analytical techniques of machine learning, deep learning, statistics, and mathematics can solve pandemic issues. The Big Data research for COVID-19 used a wide variety of data sources available publicly or privately. At the end of the discussion, we present the data source used in the past studies encompassing government official data, institutional service data, IoT generated data, online media data, and open data. We hope that this survey will clarify the role of Big Data technology in enhancing the research for COVID-19.