bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does the non-native Harlequin ladybird disrupt the feeding behaviour of the native two-spot ladybird?
Authors: Hemsley Jade A. , Holland John M. 
Published: September 2021

AbstractSince its arrival in 2004, the non-native Harlequin ladybird Harmonia axyridis (Coleoptera: Coccinellidae) has rapidly spread throughout Britain, and it is now the most common coccinellid in England. There have since been concerns about the detrimental effects it may have on native coccinellids because there is a strong correlation between the arrival of H. axyridis and the decline in native species, including the two-spot ladybird, Adalia bipunctata. However, there have been few studies of the behavioural interactions between these two species, which occupy a high-niche overlap. This study investigated if the presence of H. axyridis impacts the feeding behaviour of A. bipunctata through direct competition for aphid prey. Foraging and interactive behaviour of A. bipunctata and H. axyridis were investigated within microcosms. Adalia bipuncata exhibited a similar consumption rate and time in the presence of H. axridis, yet H. axyridis consumed 3.5 times more prey items and were seven times faster compared to A. bipuncata. Observations showed that H. axyridis does not directly disrupt the feeding behaviour of A. bipunctata, but rather indirectly excludes the native species through being a superior competitor for prey items. Results indicate that the decline in native coccinellid species may be a consequence of H. axyridis competitive advantage, but that the concept of coexistence should not be dismissed.
Inoculant, nitrogen and phosphorus improves photosynthesis and water-use efficiency in soybean production
Authors: Savala C. E. N. , Wiredu A. N. , Okoth J. O. , Kyei-Boahen S. 
Published: September 2021

AbstractSoybean yield within the Southern Africa falls below its potential despite similar climatic conditions across some agroecologies, replicable agronomic management practices and introduced improved varieties. Understanding physiological processes and water-use efficiency (WUE) of soybean offer information on bridging this yield gap. A field study was conducted in 2017 and 2018 seasons in two agroecologies (Angonia and Ruace) in Mozambique to evaluate the effects of Bradyrhizobium diazoefficiens strain USDA110 formerly known as Bradyrhizobium japonicum inoculant, nitrogen and phosphorus on nodulation, physiology and yield of non-promiscuous (Safari) and promiscuous (TGx 1740-2F) soybean varieties. Data on transpiration, photosynthesis, leaf area index, radiation interception and WUE from the beginning of flowering to maturity were collected. Transpiration rate varied considerably with interaction between locations, growth stages, varieties and treatments. At podding, phosphorus-treated soybean at Angonia transpired less (6.3 mmol/m2/s) than check plants (6.6 mmol/m2/s). Photosynthesis rate and WUE were distinct with variety, growth stages and inputs within agroecologies. For instance, in Angonia 2018 season, phosphorus fertilized TGx 1740-2F photosynthesized more at flowering (25.3 μmol/m2/s) while the lowest was phosphorus-treated Safari at podding with 17.2 μmol/m2/s. At the same site in 2017, inoculated soybean photosynthesized more at 22.8 μmol/m2/s leading to better WUE of 3.6 that corresponded to 2894 kg/ha yield. Overall, soybean WUE was higher when inoculated than N-treated, while P application yielded better. Results from this study will complement breeders’ effort in developing phosphorus efficient varieties suited for a wide range of changing climatical conditions.
Dynamic relationships between depressive symptoms and insulin resistance over 20 years of adulthood
Authors: Wu Che-Yuan , Cogo-Moreira Hugo , MacIntosh Bradley J. , Edwards Jodi D. , Krance Saffire H. , Eid Michael , Schreiner Pamela J. , Launer Lenore J. , Swardfager Walter 
Published: September 2021

AbstractBackgroundBidirectional longitudinal relationships between depression and diabetes have been observed, but the dominant direction of their temporal relationships remains controversial.MethodsThe random-intercept cross-lagged panel model decomposes observed variables into a latent intercept representing the traits, and occasion-specific latent ‘state’ variables. This permits correlations to be assessed between the traits, while longitudinal ‘cross-lagged’ associations and cross-sectional correlations can be assessed between occasion-specific latent variables. We examined dynamic relationships between depressive symptoms and insulin resistance across five visits over 20 years of adulthood in the population-based Coronary Artery Risk Development in Young Adults (CARDIA) study. Possible differences based on population group (Black v. White participants), sex and years of education were tested. Depressive symptoms and insulin resistance were quantified using the Center for Epidemiologic Studies Depression (CES-D) scale and the homeostatic model assessment for insulin resistance (HOMA-IR), respectively.ResultsAmong 4044 participants (baseline mean age 34.9 ± 3.7 years, 53% women, 51% Black participants), HOMA-IR and CES-D traits were weakly correlated (r = 0.081, p = 0.002). Some occasion-specific correlations, but no cross-lagged associations were observed overall. Longitudinal dynamics of these relationships differed by population groups such that HOMA-IR at age 50 was associated with CES-D score at age 55 (β = 0.076, p = 0.038) in White participants only. Longitudinal dynamics were consistent between sexes and based on education.ConclusionsThe relationship between depressive symptoms and insulin resistance was best characterized by weak correlations between occasion-specific states and enduring traits, with weak evidence that insulin resistance might be temporally associated with subsequent depressive symptoms among White participants later in adulthood.
Disentangling the links between gastric emptying and binge eating v. purging in eating disorders using a case-control design
Authors: Keel Pamela K. , Eckel Lisa A. , Hildebrandt Britny A. , Haedt-Matt Alissa A. , Murry Daryl J. , Appelbaum Jonathan , Jimerson David C. 
Published: September 2021

AbstractBackgroundPrior work supports delayed gastric emptying in anorexia nervosa and bulimia nervosa (BN) but not binge-eating disorder, suggesting that neither low body weight nor binge eating fully accounts for slowed gastric motility. Specifying a link between delayed gastric emptying and self-induced vomiting could offer new insights into the pathophysiology of purging disorder (PD).MethodsWomen (N = 95) recruited from the community meeting criteria for DSM-5 BN who purged (n = 26), BN with nonpurging compensatory behaviors (n = 18), PD (n = 25), or healthy control women (n = 26) completed assessments of gastric emptying, gut peptides, and subjective responses over the course of a standardized test meal under two conditions administered in a double-blind, crossover sequence: placebo and 10 mg of metoclopramide.ResultsDelayed gastric emptying was associated with purging with no main or moderating effects of binge eating in the placebo condition. Medication eliminated group differences in gastric emptying but did not alter group differences in reported gastrointestinal distress. Exploratory analyses revealed that medication caused increased postprandial PYY release, which predicted elevated gastrointestinal distress.ConclusionsDelayed gastric emptying demonstrates a specific association with purging behaviors. However, correcting disruptions in gastric emptying may exacerbate disruptions in gut peptide responses specifically linked to the presence of purging after normal amounts of food.
Protest and Social Policies for Outsiders: The Expansion of Social Pensions in Latin America
Authors: CICCIA ROSSELLA , GUZMÁN-CONCHA CÉSAR 
Published: September 2021

AbstractThe expansion of social pensions in Latin America was part of a larger process aimed at extending protections to informal workers and other individuals not covered by social insurance. These reforms were enacted by governments of different colours, and varied considerably with regard to the scope of the new programmes. While previous comparative studies have privileged economic factors and electoral dynamics to explain these differences, this article extends these frameworks to incorporate the interplay between contentious and institutional politics. It uses a two-step qualitative comparative analysis to investigate the long-term effect of protests on reforms extending the coverage of social pensions under different constellations of political, economic and institutional conditions in 18 Latin American countries (2000-2011). The results show that protest was present in almost all configurations of expansion, but that its effect was contingent on the ideology of governments, the levels of political competition and the strength of unions.
Integrating qualitative and quantitative analyses of stance: A case study of Englishthat/zero variation
Authors: Gadanidis Timothy , Kiss Angelika , Konnelly Lex , Pabst Katharina , Schlegl Lisa , Umbal Pocholo , Tagliamonte Sali A. 
Published: September 2021

AbstractPrevious work has shown that stance—the way speakers position themselves with respect to what they are talking about and who they are talking to—provides powerful insights into why speakers choose certain linguistic variants, beyond correlations with macro-social categories such as gender, ethnicity, and social class. However, as stancetaking moves are highly context-dependent, they have rarely been explored quantitatively, making the observed variable patterns difficult to generalize. This article seeks to contribute to this methodological gap by proposing a formal guide to coding stance and demonstrating how it can be operationalized quantitatively. Drawing on a corpus of eight individuals, self-recorded in three situations with varying levels of social distance, we apply this method to variation between English complementizersthatand zero (i.e. no overt complementizer), providing a replicable and theoretically grounded protocol that incorporates both quantitative and qualitative analyses in a variationist sociolinguistic study. (Stance, complementizers,that, English)*
Politics and Landscape in the Argive Plain after the Battle of Sepeia
Authors: Frullini Stefano 
Published: September 2021

AbstractModern studies have emphasized the contradictory nature of the ancient traditions concerning the aftermath of the Battle of Sepeia (494 BC), in which the Argive army was destroyed by the Spartans. This article tackles the most significant point of agreement in these traditions: the theme of Argive ‘oligandry’, the demographic crisis caused by the battle. An analysis conducted on the basis of Ansley J. Coale and Paul Demeny’s Model Life Tables shows that the real impact of the demographic crisis was felt in the age structure of Argos’ population rather than in the sheer size of its citizen body. Consequently, this article argues that the political ramifications of the battle originated not from the demographic crisis alleged by the tradition, but from the state of powerlessness and regional isolation into which Argos was plunged by the defeat of 494. This argument, which supports a reappraisal of Plutarch’s(De mul. vir.4) version of Argos’ response to Sepeia, also helps explain why Argos embraced a markedly aggressive foreign policy towards the towns of the plain in the following decades.
Barriers to Help Seeking among Victims of Elder Abuse: A Scoping Review and Implications for Public Health Policy in Canada
Authors: Gill Jessica K. 
Published: September 2021

AbstractElder abuse is a serious public health concern requiring immediate intervention; however, the under-reporting of elder abuse by victims to formal and informal networks remains a major obstacle. This scoping review aims to identify barriers to help seeking that older adults experiencing abuse confront. The goal is to inform public policies and practices in the Canadian context and identify research gaps in the extant literature. Seven scholarly databases were searched from which 12 articles met the inclusion criteria and were extracted for analysis. The findings from this scoping review revealed three levels at which barriers exist: individual focused, abuser/family focused, and community/culture focused barriers. The results suggest that there are several complex obstacles that older adults face when contemplating disclosure of abuse. Future research into help seeking in the Canadian context should more readily incorporate the voices of elder abuse victim-survivors to develop effective assessment strategies and responsive service provisions.
Marqueurs reformulatifs en français et en russe: de quelques intéressants parallélismes entre les deux langues
Authors: Guryev Alexander 
Published: September 2021

RésuméCet article analyse, dans une perspective comparative, deux classes de marqueurs de reformulation en français et en russe. La première est construite autour d’un indéfini enautre(rus.inoj) : fr.autrement dit,en d’autres termes; rus.inače govorja,inymi slovami; la seconde est historiquement dérivée d’une clause verbale finiece + est(rus.to + estʹ) : fr.c’est-à-dire, rus.to estʹ. Il sera démontré que le français et le russe partagent bon nombre de propriétés dans le fonctionnement de ces marqueurs, qu’il s’agisse de leur fonctionnement grammatical ou sémantico-pragmatique. Il sera aussi argumenté que les marqueurs de la deuxième classe font l’objet d’un stade de grammaticalisation, mais aussi de pragmaticalisation, plus avancé et sont, par conséquent, plus appropriés à des interactions spontanées que les marqueurs construits autour d’un indéfini enautre.
Polarity Determination in EBSD Patterns Using the Hough Transformation
Authors: Zscheckel Tilman , Wisniewski Wolfgang , Rüssel Christian 
Published: September 2021

Abstract
Currently, the automated electron backscatter diffraction (EBSD) technique only allows the differentiation of the Laue groups based on an electron backscatter pattern (EBSP). This article shows that information concerning the lattice plane polarity is not only stored in the EBSP, but also in the Hough transformed EBSP where it can be easily accessed for automated evaluation. Polar Kikuchi bands lead to asymmetric peaks during the Hough transformation that are dependent on the atomic number difference of the involved atoms. The effect can be strong enough to be detected when evaluating the intensities of the regular excess and deficiency lines. Polarity detection from the Hough transformation of an EBSP cannot only enhance the utility of the EBSD technique and expand the information gained from it, but also illustrates a path toward automated polarity determination during EBSD scans.
From Process to Centuries: Upscaling Field‐Calibrated Models of Fluvial Bedrock Erosion
Authors: Beer Alexander R. , Turowski Jens M. 
Published: September 2021

AbstractFluvial bedrock erosion formulas lack validation over space and time. We explore the performance of field‐calibrated models at the patch‐scale (<1) and from minutes to centuries. At the hour to annual scales (in 1‐min resolution), we verify predictions using linked discharge, bedload transport and at‐a‐point erosion, together with spatial erosion from a mountain streambed. Local and spatial erosion linearly scale with bedload mass. The unit stream power model (USP) fails to describe erosion dynamics without a threshold for its onset. Extrapolating over the decadal scale (14 years of discharge and bedload data), scaled models predict up to 12% of erosion for two exceptional floods. Erosion predictions for a bi‐centennial discharge varied over four orders of magnitude (extrapolated from 32.5 years discharge and 16 years bedload data at 10‐min resolution). Bi‐centennial erosion predictions summing up to 1 m for bedload models versus 0.1 m for USP highlight the likely dominance of large events in setting long‐term erosion under sediment‐starved conditions.
The Polar Cusp Seen by Cluster
Authors: Pitout F. , Bogdanova Y. V. 
Published: September 2021

AbstractThe investigation of the magnetospheric polar cusps was one of the main objectives of the Cluster mission. The four satellites have crossed those regions numerous times over the years and, with their suitable instrumentation, favorable orbits, and unique multipoint measurements, many aspects of the cusp have been unveiled. The first of those is its highly dynamic nature. With four satellites, whatever their altitude and thus their configuration, the spatial/temporal ambiguity has been lifted and a completely new insight into the motion of the cusp and evolution of the transient small‐scale structures within it was given. Second, the high altitude or exterior cusp, its properties and dynamics, magnetic configuration, the energetic particles observed within, and its boundary with the magnetosheath were characterized in a number of case studies and on a statistical basis. Third, the Cluster cusp observations brought a fresh eye on the reconnection process at the magnetopause, including its location and spatio‐temporal variability. Finally, the complete payload with particle, field and wave detectors have made it possible to treat cusp as a plasma physics laboratory to progress our understanding of wave‐particle interaction and turbulence within the cusp. We have no choice but to note that Cluster has been extremely successful for all these matters.
Effect of Merging Multiscale Models on Seismic Wavefield Predictions Near the Southern San Andreas Fault
Authors: Ajala R. , Persaud P. 
Published: September 2021

AbstractUpdating Earth models used by the scientific community in geologic studies and hazard assessment has a significant societal impact but is computationally prohibitive due to the large spatial scale. The advent of urban seismology allowed rapid development of local high‐resolution models using short‐term dense seismic arrays to become conventional. To incorporate the details in these local models in community models, we developed a technique for constructing window taper functions like the cosine taper in arbitrarily shaped spatial domains on regular grids. We apply our algorithm to the problem of low‐frequency ground shaking estimation near the southernmost San Andreas fault by creating two hybrid models. These models consist of basin‐scale (top 10 km or less) high‐resolution models developed using controlled source data embedded into two popular Southern California Earthquake Center community models. We evaluate the models by computing long period (6–30 s) wavefield energy misfits using 11 earthquakes with moment magnitudes between 3.5 and 5.5 not used in developing any of the models under consideration. One of the hybrid models produces an ∼24% decrease while the other has an ∼0.6% increase in the overall median misfit relative to their original community models. The overlapping misfit values between the models and variability in waveform fit for different events and stations emphasize the difficulties in model validation. Our approach can merge any type of gridded multiscale and multidimensional datasets, and represents a valuable tool for modeling in the computational sciences.
RBD-homodimer, a COVID-19 subunit vaccine candidate, elicits immunogenicity and protection in rodents and nonhuman primates
Authors: Pan Xiaoyan , Shi Jian , Hu Xue , Wu Yan , Zeng Liang , Yao Yanfeng , Shang Weijuan , Liu Kunpeng , Gao Ge , Guo Weiwei , Peng Yun , Chen Shaohong , Gao Xiaoxiao , Peng Cheng , Rao Juhong , Zhao Jiaxuan , Gong Cheng , Zhou Hui , Lu Yudong , Wang Zili , Hu Xiliang , Cong WenJuan , Fang Lijuan , Yan Yongxiang , Zhang Jing , Xiong Hui , Yi Jizu , Yuan Zhiming , Zhou Pengfei , Shan Chao , Xiao Gengfu 
Published: September 2021

AbstractThe pandemic of COVID-19 caused by SARS-CoV-2 has raised a new challenges to the scientific and industrious fields after over 1-year spread across different countries. The ultimate approach to end the pandemic is the timely application of vaccines to achieve herd immunity. Here, a novel SARS-CoV-2 receptor-binding domain (RBD) homodimer was developed as a SARS-CoV-2 vaccine candidate. Formulated with aluminum adjuvant, RBD dimer elicited strong immune response in both rodents and non-human primates, and protected mice from SARS-CoV-2 challenge with significantly reducing viral load and alleviating pathological injury in the lung. In the non-human primates, the vaccine could prevent majority of the animals from SARS-CoV-2 infection in the respiratory tract and reduce lung damage. In addition, antibodies elicited by this vaccine candidate showed cross-neutralization activities to SARS-CoV-2 variants. Furthermore, with our expression system, we provided a high-yield RBD homodimer vaccine without additional biosafety or special transport device supports. Thus, it may serve as a safe, effective, and low-cost SARS-CoV-2 vaccine candidate.
Efficient access to aliphatic esters by photocatalyzed alkoxycarbonylation of alkenes with alkyloxalyl chlorides
Authors: Chen Jian-Qiang , Tu Xiaodong , Tang Qi , Li Ke , Xu Liang , Wang Siyu , Ji Mingjuan , Li Zhiming , Wu Jie 
Published: September 2021

AbstractAliphatic esters are essential constituents of biologically active compounds and versatile chemical intermediates for the synthesis of drugs. However, their preparation from readily available olefins remains challenging. Here, we report a strategy to access aliphatic esters from olefins through a photocatalyzed alkoxycarbonylation reaction. Alkyloxalyl chlorides, generated in situ from the corresponding alcohols and oxalyl chloride, are engaged as alkoxycarbonyl radical fragments under photoredox catalysis. This transformation tolerates a broad scope of electron-rich and electron-deficient olefins and provides the corresponding β-chloro esters in good yields. Additionally, a formal β-selective alkene alkoxycarbonylation is developed. Moreover, a variety of oxindole-3-acetates and furoindolines are prepared in good to excellent yields. A more concise formal synthesis of (±)-physovenine is accomplished as well. With these strategies, a wide range of natural-product-derived olefins and alkyloxalyl chlorides are also successfully employed.
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding
Authors: Yu Fangjun , Wang Zhigang , Zhang Tianpeng , Chen Xun , Xu Haiman , Wang Fei , Guo Lianxia , Chen Min , Liu Kaisheng , Wu Baojian 
Published: September 2021

AbstractThe role of intestine clock in energy homeostasis remains elusive. Here we show that mice with Bmal1 specifically deleted in the intestine (Bmal1iKO mice) have a normal phenotype on a chow diet. However, on a high-fat diet (HFD), Bmal1iKO mice are protected against development of obesity and related abnormalities such as hyperlipidemia and fatty livers. These metabolic phenotypes are attributed to impaired lipid resynthesis in the intestine and reduced fat secretion. Consistently, wild-type mice fed a HFD during nighttime (with a lower BMAL1 expression) show alleviated obesity compared to mice fed ad libitum. Mechanistic studies uncover that BMAL1 transactivates the Dgat2 gene (encoding the triacylglycerol synthesis enzyme DGAT2) via direct binding to an E-box in the promoter, thereby promoting dietary fat absorption. Supporting these findings, intestinal deficiency of Rev-erbα, a known BMAL1 repressor, enhances dietary fat absorption and exacerbates HFD-induced obesity and comorbidities. Moreover, small-molecule targeting of REV-ERBα/BMAL1 by SR9009 ameliorates HFD-induced obesity in mice. Altogether, intestine clock functions as an accelerator in dietary fat absorption and targeting intestinal BMAL1 may be a promising approach for management of metabolic diseases induced by excess fat intake.