bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of an interprofessional education program in pediatric dentistry, medicine, and nursing
Authors: Ramos‐Gomez Francisco , Kinsler Janni J. , Askaryar Hamida , Verzemnieks Inese , Garell Cambria 
Published: March 2021

AbstractPurposeThe purpose of this study was to assess whether the Strategic Partnership for Interprofessional Collaborative Education in the Pediatric Dentistry (SPICE‐PD) program at the UCLA School of Dentistry positively affected interprofessional experiences and practice patterns of pediatric and general dentistry residents, pediatric medical residents, and pediatric nurse practitioner students (PNPs).MethodsData collection included a year‐end online survey given to participants in the interprofessional program upon graduation from their UCLA dental/medical/nursing programs. Of the 318 participants who were recruited into SPICE‐PD, 208 (65%; 208/318) completed the survey. Chi‐square tests were used to assess differences in key outcome variables by dental/medical specialty.ResultsMost dental, medical, and nursing participants thought SPICE‐PD helped them learn to work more effectively with interprofessional colleagues and reported knowing more about the abilities and contributions of other health professionals as a result of the program. While most pediatric medical residents and PNPs thought SPICE‐PD improved their skills to screen for early childhood caries (N = 91% and N = 100%), PNPs were more likely than pediatric medical residents to report SPICE‐PD improved their skills to apply fluoride varnish (98% versus 72%; p < 0.001). Almost all pediatric medical residents and PNPs thought primary care providers should incorporate oral health into routine patient care and provide referrals to dental professionals when necessary.ConclusionIncreased interprofessional education and coordination of care through programs such as SPICE‐PD can help bridge the gap between dental and medical care and lead to improved oral health outcomes and more comprehensive and preventive patient care.
Rapid diagnostic testing for SARS‐CoV‐2: Validation and comparison of three point‐of‐care antibody tests
Authors: Strand Rasmus , Thelaus Louise , Fernström Nils , Sunnerhagen Torgny , Lindroth Ylva , Linder Adam , Rasmussen Magnus 
Published: March 2021

AbstractWith the emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a need for diagnostic tests has surfaced. Point‐of‐care (POC) antibody tests can detect immunoglobulin (Ig) G and M against SARS‐CoV‐2 in serum, plasma, or whole blood and give results within 15 min. Validation of the performance of such tests is needed if they are to be used in clinical practice. In this study, we evaluated three POC antibody tests. Convalescent serum samples from 47 reverse transcription‐polymerase chain reaction (RT‐PCR) verified patients with coronavirus disease 2019 (COVID‐19) collected at least 28 days post RT‐PCR diagnosis as well as 50 negative pre‐COVID‐19 controls were tested. The three tests (denoted the J‐, N‐, and Z‐tests) displayed the sensitivities of 87%, 96%, and 85%, respectively, for the detection of IgG. All tests had the same specificity for IgG (98%). The tests did not differ significantly for the detection of IgG. The sensitivities for IgM were lower (15%, 67%, and 70%) and the specificities were 90%, 98%, and 90%, respectively. The positive and negative predictive values were similar among the tests. Our results indicate that these POC antibody tests might be accurate enough to use in routine clinical practice.
Creative Thinking Counseling Teaching Program can Improve the Creativity, Creative Tendency, and Self‐Concept of Grade 7 Students: A Quasi‐Experimental Study
Authors: Huang Shih‐Yuan , Ko Pei‐Jung , Lin Hsiao‐Hui , Dai Ru‐Huei , Chen Hsueh‐Chih 
Published: March 2021

AbstractWe developed a Creative Thinking Counseling Teaching Program (CTCTP) for Grade 7 students using the self‐concept of the counseling curriculum as the primary development axis and investigated how this program influences creativity, creative tendency, and self‐concept. We adopted a non‐equivalent control group pre‐test–post‐test quasi‐experimental design. Of 133 participants, the experimental group (67 students) received an eight‐week CTCTP, involving a 45‐minute class per week; the control group (66 students) participated in general counseling. Research instruments included the NTCT‐Figural Exercises (NTCT‐Figural), The Williams Assessment of Creative Tendency (WACT), and Elementary School Student Self‐Concept Scale (SCS). Personal reflection learning sheets, learning achievement assessment, and course feedback forms were used to qualitatively analyze the learning effectiveness and feasibility of the teaching program. Results showed that the experimental group had significantly higher scores than the control group for creativity, creative tendency, and self‐concept. Further mediation analysis showed that the effects of the teaching experiment were not the result of mutual mediation effects. Students’ feedback on the CTCTP learning process suggested that it had a positive effect on the development of students’ creativity, creative tendency, and self‐concept, while also meeting their learning needs. We propose recommendations for application in teaching practice and future research.
Hexadecyl trimethyl ammonium bromide‐modified 4‐mercaptopyridinde mixture for enhancement of corrosion resistance: Experimental and molecular dynamics simulation study
Authors: Han Peng , Wang Xiuzhi , Xu Chenyang , Liu Ruiping , Fan Lei , Song Liying , Zhang Junqing , Zhang Lei 
Published: March 2021

AbstractThe synergistic effect between 4‐mercaptopyridine (4MP) and hexadecyl trimethyl ammonium bromide (C16TAB) was studied using electrochemical method combined with weight loss measurements. The spontaneous adsorption of the inhibitor follows Langmuir isotherm. They work as mix‐type inhibitor with predominant control of the cathodic process. The inhibition efficiency of the inhibitor mixture (C16TAB–MP) is higher than those of the individual component and increases with increasing of the inhibitor concentration. 4MP molecule adsorb on metal chemically through N and S atom, whereas C16TAB molecule through physisorption of N atom, after they coadsorbed on the iron surface, both of them adsorb through chemisorption. The distance between N‐Fe and S‐Fe in C16TAB–MP is shorter than that in the 4MP or C16TAB containing system. C16TAB and 4MP show good synergistic effect.
Oxidation with a “Stopover” – Stable Zwitterions as Intermediates in the Oxidation of α‐Tocopherol (Vitamin E) Model Compounds to their Corresponding ortho‐Quinone Methides
Authors: Böhmdorfer Stefan , Rosenau Thomas 
Published: March 2021

AbstractAs a prominent member of the vitamin E group, α‐tocopherol is an important lipophilic antioxidant. It has a special oxidation chemistry that involves phenoxyl radicals, quinones and quinone methides. During the oxidation to the ortho‐quinone methide, an intermediary zwitterion is formed. This aromatic intermediate turns into the quinone methide by simply rotating the initially oxidized, exocyclic methyl group into the molecule's plane. This initial zwitterionic intermediate and the quinone methide are not resonance structures but individual species, whose distinct electronic structures are separated by a mere 90° bond rotation. In this work, we hindered this crucial rotation, by substituting the affected methyl group with alkyl or phenyl groups. The alkyl groups slowed down the conversion to the quinone methide by 18‐times, while the phenyl substituents, which additionally stabilize the zwitterion electronically, completely halted the conversion to the quinone methide at −78 °C, allowing for the first time the direct observation of a tocopherol‐derived zwitterion. Employing a 13C‐labeled model, the individual steps of the oxidation sequence could be observed directly by NMR, and the activation energy for the rotation could be estimated to be approximately 2.8 kcal/mol. Reaction rates were solvent dependent, with polar solvents exerting a stabilizing effect on the zwitterion.The observed effects confirmed the central relevance of the rotation step in the change from the aromatic to the quinoid state and allowed a more detailed examination of the oxidation behavior of tocopherol. The concept that a simple bond rotation can be used to switch between an aromatic and an anti‐aromatic structure could find its use in molecular switches or molecular engines, driven by the specific absorption of external energy.
Synthesis and characterization of poly(urethane)/silver composites via in situ polymerization
Authors: Yağmur Hatice Karaer , Kaya İsmet 
Published: March 2021

AbstractIn this study, poly(urethane)/silver (PU/Ag) composites were synthesized in dimethylformamide (DMF) with no essential extra reducing agents. The reaction medium DMF is acting as both a diluent and reducing agent for silver particles. Composites (PU/Ag) were synthesized by in situ polymerization in the existence of different amounts of silver nitrate. The formation of PU/Ag composites was approved by ultraviolet–visible (UV–vis) spectrometer, Fourier transform infrared (FTIR) spectroscopy, and X‐ray diffraction (XRD) analyses, scanning electron microscopy–energy dispersive X‐ray (SEM–EDX) analyses, thermogravimetric analysis/differential thermal analysis (TGA‐DTA), and differential scanning calorimetry. The conductivity measurements of PU and composites were done with the four‐point probe technique using a Keithley 2400 electrometer. The conductivity values of the undoped PU, PU5, PU10, and PU20 were about 1.18 × 10−7, 2.2 × 10−6, 2.3 × 10−7, and 1.25 × 10−7 S cm−1, respectively. The presence of silver particles was approved by UV–vis spectroscopy, EDX, and XRD. The formation of silver particles was determined by UV–Vis absorption spectra of the polymer matrix. According to TGA, it was observed that composites have higher thermal stability than polyurethane.
Recruiting and retaining school psychologists: The experiences of district level administrative supervisors
Authors: Young Ellie L. , Butler Rachel , Smith Timothy B. , Hilton Sterling C. , Smith Alivia 
Published: March 2021

AbstractA shortage of school psychologists has been evident since the profession was initially recognized as a distinct field, and there is insufficient research on what current administrative supervisors are doing to address this problem. This qualitative study examined the perceptions of district level administrative supervisors regarding recruitment and retention of school psychologists. Participants reported the following: (a) school psychology graduate programs do not producing enough school psychologists, (b) administrators are challenged to find enough school psychologists to hire, (c) neighboring school districts compete to hire candidates, and (d) administrators recruit and retain in a worker's market that favors the school psychologist. These administrative supervisors also communicated a sense that they had little influence over the shortage. Actions within the administrators' control included developing close relationships with graduate programs for successful recruiting, creating appealing workloads that matched salaries, being responsive to the needs of their current school psychologists, and offering job flexibility.
An evaluation of the impact of aggressive diabetes and hypertension management on chronic kidney diseases at the population level: a simulation analysis
Authors: Ansah John Pastor , Wei Shawn Tan Yi , Min Tessa Lui Shi 
Published: March 2021

AbstractAssociated with undesirable clinical outcomes including cardiovascular events, kidney failure, and poor quality of life, Chronic Kidney Disease (CKD) is an emerging noncommunicable disease globally. Treatment costs and CKD complications result in an enormous burden on the healthcare system. Randomized control trials suggest that CKD outcomes can improve if individuals with diabetes and hypertension are adequately managed, raising what‐if questions at the population level. This research aims to explore the impact of aggressive diabetes and hypertension management on CKD outcomes. Based on data from randomized control trials, the Singapore Renal Registry, and the literature, a system dynamics simulation model was developed. Results suggest that the key to reducing the burden of CKD at the population level is identifying and aggressively managing individuals with prehypertension and hypertension to reduce risk of developing CKD events. Combined interventions focusing on aggressive diabetes and hypertension management have the biggest impact on CKD outcomes. © 2021 System Dynamics Society
Design, Synthesis and Antidiabetic Activity of Biphenylcarbonitrile‐Thiazolidinedione Conjugates as Potential α‐Amylase Inhibitors
Authors: Rathod Chirag H. , Nariya Pankajkumar B. , Maliwal Deepika , Pissurlenkar Raghuvir R. S. , Kapuriya Naval P. , Patel Anilkumar S. 
Published: March 2021

AbstractThe α‐amylase inhibition has been considered as an effective therapeutic approach against chronic Type 2 Diabetes mellitus (DM). In the present study, a series of biphenylcarbonitrile‐thiazolidinedione conjugates have been synthesized and evaluated for their antidiabetic activity via α‐amylase inhibition. It was found that most of the conjugates (14 a–j) exhibited significant α‐amylase inhibition activity compared to the standard drug Acarbose. Off these, compound 14 b, 14 c and 14 d were most potent with IC50 value 0.13 μM, 0.15 μM and 0.13 μM respectively. To ascertain ligand‐receptor interactions, the in silico molecular docking studies of these conjugates (14 a–j) have been carried out into the Acarbose active site of barley (malt) α‐amylase enzyme. The results have shown fair corroboration between significant α‐amylase inhibition activity of 14 b, 14 c and 14 d and their docking scores compared to the standard drug Acarbose. This study demonstrated that biphenylcarbonitrile‐thiazolidinedione conjugate could be a plausible pharmacophore for targeting α‐amylase for the treatment of Type 2 Diabetes mellitus.
Enhanced Electrochemical Properties of Lithium‐Rich Cathode Materials by Magnesium Borate Surface Coating
Authors: Bai Maohui , Hu Lina , Liang Yuhao , Hong Bo , Lai Yanqing 
Published: March 2021

AbstractMagnesium borate oxide (MBO) coated lithium‐rich layered Li1.2Mn0.54Co0.13Ni0.13O2 particles are synthesized via a wet chemical coating method. The X‐ray diffraction, scanning electron microscopy, energy dispersive spectroscopy, transmission electron microscopy, and X‐ray photoelectron spectrometer results indicate that the cathode particles are uniformly covered with a MBO layer. The results of charge/discharge tests show that the MBO‐coated electrode has enhanced electrochemical properties both in rate capability and cycling stability compared to the bare one. Specifically, 3 wt. % MBO‐coated sample has capacity retention of 98.3 %, much more than the bare one of only 79.2 % after 100 cycles at 1 C. Furthermore, the MBO‐coated electrode retains a superior high‐rate capacity of 90 mAh g−1 at 10 C. The remarkably enhanced rate capability and cycling stability of MBO‐coated electrode is ascribed to the MBO coating layer efficiently isolating the bulk Li1.2Mn0.54Co0.13Ni0.13O2 from direct contact with the electrolyte, and facilitating both charge transfer reaction and the kinetics of lithium ion diffusion through the surface layer.
New Family of Heptanuclear Lanthanide {Ln7} Clusters: Synthesis, Structure, and Magnetic Studies
Authors: Shukla Pooja , Pal Tapan K. , Sahoo Subash Chandra , Du Ming‐Hao , Kong Xiang‐Jian , Das Sourav 
Published: March 2021

AbstractA new family of heptanuclear lanthanide complex [Ln7(L)2(LH)4(dbm)5(OH)2(CH3OH)4]⋅xCHCl3⋅yCH3OH⋅zH2O {Ln=TbIII (1), DyIII (2) and ErIII (3) and LH3=(E)‐2‐(hydroxymethyl)‐6‐(((2‐hydroxyphenyl) imino) methyl)‐4‐methylphenol} [in 1, x=6, y=3, z=3; in 2, x=5, y=1, z=6; and in 3, x=4, z=2] has been prepared in presence of lanthanide chloride(III) salts and β‐diketonate co‐ligand dibenzoylmethane (dbm). Single crystal XRD reveals heptanuclear ensemble formed by collective action of two fully deprotonated [L]3− ligands, four double deprotonated [LH]2−, two μ3‐OH− ligands, five anionic [dbm]− β‐diketonate co‐ligands and two terminal methanol solvent molecules. This heptanuclear unit comprises of two [Dy4(μ2‐O)5(μ3‐OH)]+6 core sharing a common metal vertex Dy1 through which centre of inversion has passed for overall molecule. All the complexes have been magnetically characterized and dynamic AC magnetic studies reveals slow relaxation of magnetism present in dysprosium analogue (2).
Making Policies with Data: The Legacy of the PoliVisu Project
Authors: Acar Freya , Raes Lieven , Rosseau Bart , Satta Matteo 
Published: March 2021

AbstractThe PoliVisu project has the goal to investigate the potential of data use and visualisation in urban policy making. The project has explored how data supported policy making is adopted by public administrations and what we can learn from their experience. This is done by enrolling pilot cases with different and specific policy problems. From the experience of the PoliVisu pilots the influence and added value of data in the policy making process is assessed. Considering the recent “shake” in data production and use, PoliVisu has adopted four driving questions, as follow: what are the new roles data can play in the policy making process?, What is the added value of data for policy making? How can innovative visualisations contribute to improve the use of data in policy making processes? To what extent can an increased adoption of data affect the policy making process? How is the data shake affecting the involvement of non-institutional actors in the policy making process? This paper explores these questions, by presenting the experiences and the lessons learnt, also focussing on specific pilots’ initiatives and results.
Structural and Magnetic Characterizations of Ruddlesden–Popper Family (Ca2-xNdxMnO4) Compound Synthesized by Ceramic Route
Authors: Issaoui H. , Issaoui F. , Dhahri E. , Hlil E. K. 
Published: March 2021

AbstractIn this work, we were interested in the Ca2−xNdxMnO4 compounds when (0.1 ≤ x ≤ 0.4). These oxides are synthesized through the solid-state method. In this study, we investigated the evolution of the structure, the magnetic properties and the Mn3+/Mn4+ ratio with the Nd content. The morphological study shows a decrease in the size of the grain in relation to x. The X-ray diffraction reveals a transition from the tetragonal phase to the orthorhombic phase when x = 0.4. Magnetic measurements have been taken for all the compounds in the temperature range between 2 and 300 K. The temperature-dependent magnetic susceptibility shows the presence of three transitions TN, TC and TCO. A dramatic difference in magnetic susceptibility between ZFC and FC was observed below the Neel temperatures for Ca2-xNdxMnO4, which shows the onset of a ferromagnetic moment below these temperatures. This moment is caused by the Dzyaloshinskii–Moriya interaction.
A comprehensive review on the carcinogenic potential of bisphenol A: clues and evidence
Authors: Khan Nadeem Ghani , Correia Jacinta , Adiga Divya , Rai Padmalatha Satwadi , Dsouza Herman Sunil , Chakrabarty Sanjiban , Kabekkodu Shama Prasada 
Published: March 2021

AbstractBisphenol A [BPA; (CH3)2C(C6H4OH)2] is a synthetic chemical used as a precursor material for the manufacturing of plastics and resins. It gained attention due to its high chances of human exposure and predisposing individuals at extremely low doses to diseases, including cancer. It enters the human body via oral, inhaled, and dermal routes as leach-out products. BPA may be anticipated as a probable human carcinogen. Studies using in vitro cell lines, rodent models, and epidemiological analysis have convincingly shown the increasing susceptibility to cancer at doses below the oral reference dose set by the Environmental Protection Agency for BPA. Furthermore, BPA exerts its toxicological effects at the genetic and epigenetic levels, influencing various cell signaling pathways. The present review summarizes the available data on BPA and its potential impact on cancer and its clinical outcome.
The role of diet in the pathophysiology and management of irritable bowel syndrome
Authors: El-Salhy Magdy , Patcharatrakul Tanisa , Gonlachanvit Sutep 
Published: March 2021

AbstractIrritable bowel syndrome (IBS) is a chronic gastrointestinal (GI) disorder that reportedly affects 5% to 20% of the world population. The etiology of IBS is not completely understood, but diet appears to play an important role in its pathophysiology. Asian diets differ considerably from those in Western countries, which might explain differences in the prevalence, sex, and clinical presentation seen between patients with IBS in Asian and Western countries. Dietary regimes such as a low-fermentable oligo-, di-, monosaccharides, and polyols (FODMAP) diet and the modified National Institute for Health and Care Excellence (NICE) diet improve both symptoms and the quality of life in a considerable proportion of IBS patients. It has been speculated that diet is a prebiotic for the intestinal microbiota and favors the growth of certain bacteria. These bacteria ferment the dietary components, and the products of fermentation act upon intestinal stem cells to influence their differentiation into enteroendocrine cells. The resulting low density of enteroendocrine cells accompanied by low levels of certain hormones gives rise to intestinal dysmotility, visceral hypersensitivity, and abnormal secretion. This hypothesis is supported by the finding that changing to a low-FODMAP diet restores the density of GI cells to the levels in healthy subjects. These changes in gut endocrine cells caused by low-FODMAP diet are also accompanied by improvements in symptoms and the quality of life.
Removal of two cytostatic drugs: bleomycin and vincristine by white-rot fungi – a sorption study
Authors: Jureczko Marcelina , Przystaś Wioletta 
Published: March 2021

Abstract
Purpose
Cytostatic drugs cannot be easily removed by conventional sewage treatment plants, resulting in their ultimate release into aquatic systems where they become a threat. Thus, new technologies which can be used to eliminate these drugs more effectively before they enter the environment are increasingly important. Fungal treatment of wastewaters is a promising and environmentally friendly technology for pharmaceutical remediation. The aim of this work is to examine the biosorption of two cytostatics, bleomycin and vincristine, in the aqueous solution by fungal biomass.

Methods
Five white-rot fungi were used in this study: Fomes fomentarius (CB13), Hypholoma fasciculare (CB15), Phyllotopsis nidulans (CB14), Pleurotus ostreatus (BWPH), and Trametes versicolor (CB8). Tests were conducted on different types of biomass (alive and dead – autoclaved) and in various physico-chemical conditions: varied drug concentrations (5, 10 and 15 mg/L), temperatures (from 15.4 to 29.6 °C), and pH (from 3.2 to 8.8).

Results
The results showed that among alive biomass, T. versicolor (CB8) had the greatest sorption ability for bleomycin and P. nidulans (CB14) worked best for vincristine. The tested sorption process could be described by a pseudo-second order kinetics model. Sorption equilibrium studies demonstrated that for bleomycin Redlich-Peterson, while for vincristine Langmuir model fitted best. The thermodynamic studies showed that the sorption process was endothermic chemisorption for bleomycin, and exothermic physisorption for vincristine. For both drugs the sorption ability increased with an increase of the pH value.

Conclusion
The biosorption on fungal biomass is a favorable alternative to conventional wastewater treatment processes for anticancer drug removal.