bluuebunny/crossref_metadata_2025_split huggingface dataset:
Four-D Models Method Validation Analysis of an Android-Based Learning Media
Authors: Yunus Yuliawati , Fransisca Monica 
Published: February 2021

Abstract
This article presents the results of validation analysis of an android-based learning media that is applied to entrepreneurship subjects which specialized in tourism majors at vocational schools in Padang. The main object of this learning media was it can be accessed via mobile phone and this learning media accessible for teachers and students anytime, anywhere. The validation analysis of learning media was obtained from media experts and content experts. The validation results were used as reference for utilization of an android-based learning media at vocational school in Padang.
The Correlation of Students’ Perception About Online Learning and Students’ Grade Point at IAIN Bukittinggi
Authors: Sesmiarni Zulfani , Ahida Ridha , Iswantir  
Published: February 2021

Abstract

Abstract. This research is aimed to find correlation between students’ perception about online learning and students’ grade point average at Tarbiyah and Teacher Training Faculty IAIN Bukittinggi. Research population was all of Tarbiyah and Teacher Training Faculty students who registered active on even semester 2019/2020 that amounted to 3.335 students. Sample was chosen 10 % of the population, 333 students, using accidental sampling technique. Research instrument used questionnaire and distributed via Google form by using media like whatsapp group and email. Based on the finding, it was founded students’ perception about online learning at Tarbiyah and Teacher Training Faculty IAIN Bukittinggi classified into good and score gotten is 64. If it is reviewed from indicators which consisted of infrastructure, education management and human resource, the score of each indicators gotten is infrastructure aspect 63 classified into good, education management aspect 61 categorized into good and human resources aspect 68 classified into good. If it is reviewed from correlation of students’ perception about online learning and students’ grade point average, correlation coefficient (r) is 0,13 which means low or weak correlation. If it is compared between count correlation coefficient and table, it can conclude r count is bigger than r table means there is correlation between students’ perception about online learning and students’ grade point average.
The use of laser radiation to stimulate the growth of kohlrabi cabbage
Authors: Sevostyanova N N , Danilovskikh M G , Vinnik L I , Trezorova O Y , Pchelina EA 
Published: February 2021

Abstract
The paper analyzes data on the use of laser radiation to stimulate the growth and development of crops, describes the biochemical basis for the transmission of coherent radiation to the cell and the cellular response. The positive effect of using a semiconductor laser with a red spectrum of action with a wavelength of 658 nm is shown by the example of kohlrabi cabbage. An increase in the mass of stems, as well as an increase in the content of proteins and carbohydrates when using laser radiation, was shown.
Economic and mathematical model of the profit of sugar production from beets
Authors: Gromkovskii A I , Gromkovskii A A , Gromkovskaia N A 
Published: February 2021

Abstract
The economic sector of sugar production from beets in Russia is currently operating in a crisis of overproduction. The volume of sugar produced over the past few years exceeds the demand of the country’s population and the need for related processing industries. This economic situation led to a decrease in the market price of sugar, the formation of a deficit of working capital of enterprises. It arose a risk for unprofitable work of sugar factories. One of the main business processes that determine the efficiency of the company’s operation is to make a profit. Based on the analysis of the specifics of sugar production from beets, a mathematical model of the sugar factory’s profit was developed. The developed model takes into account all the components of the business process of making a profit that determine the efficiency of the sugar factory. Based on the developed mathematical model, it is possible to analyze the break-even operation of a sugar factory and determine the break-even point. The obtained mathematical model allows solving problems of optimal enterprise management, optimal design and reconstruction of sugar plants, and conducting financial audits. With the help of the developed mathematical model, the production activity of three sugar factories of different production capacities and different degrees of technical equipment is studied. The economic parameters of break-even operation of the studied enterprises are determined. Comparative analysis has shown the decisive role of effective production technologies in the break-even value.
The research of one-stage particle size-reduction process of blocked frozen meat with multiple cutting tools with milling operation method
Authors: Kapovsky B R , Plyasheshnik P I , Kuznetsova T G , Lazarev A A 
Published: February 2021

Abstract
This article shows experimental data about energy demands of innovative one-stage particle size-reduction process of frozen meat, formed in blocks, with milling operation method. We researched the particle size-reduction of meat blocks (beef and pork) by tools of different construction and shape of cutting edge: a slab mill with small edge and a fitted on shaving milling tool with a hard-faced knife. This study based on results of measuring three-phase active power, used by the cutting electric drive in working condition. The article presents the calculation of the measurements of numerical characteristics (mean value and mean square deviation) of statistical samples of power values with completing particle size-reduction tool with milling tools. The research shows that placing additional sustainer, that fixes a block of meat directly near the cutting zone, leads to decrease of energy demands for the cutting process up to 20% and to lower the dispersion of power values more than three times. The data obtained during the research let work out technical requirement specification for producing a commercial prototype of cutting particle size-reduction. The data allow creating the calculate method of numerical characteristics of a random process for a load of multiple razor tool in working condition. That model is used for designing an intellectual system of management of technological process on the transfer line for meat product producing with using one-stage particle size-reduction of raw materials with the milling method.
The Cloud Resource Forecasting Model Based HMM
Authors: Liu Han , Meng Hai-Ning , Zhang Tong , Qu Yi-Lin 
Published: February 2021

AbstractOne of the most important goals for companies that provide cloud computing services is to maintain high availability on large computer systems. In order to accomplish such objective, it is necessary to discovery the reason of poor availability. Software aging is a main factor in cloud computing services, leading to software failures, poor performances and may result in system downtime. This paper investigates the software aging effects on the OpenStack cloud computing platform and describes a forecasting model based on Hidden Markov Models. The prediction analysis of the Hidden Markov Models on the key performance data of the system shows that the Hidden Markov Models has excellent predictive performance and is suitable for the prediction of the reliability of the cloud server system.
Mechanical Characterization of New Geopolymeric Materials Based on Mining Tailings and Rice Husk Ash
Authors: Huamán-Mamani F.A. , Mayta-Ponce D.L. , Rodríguez-Guillén G.P. 
Published: February 2021

Abstract
This work presents the results of the thermomechanical evaluation of geopolymeric concrete fabricated from mining tailings, rice husk ash and fine sand. Ten types of geopolymeric concrete were studied and the relationship between the initial volumetric concentrations of the components in the mixtures and the maximum resistance in uniaxial compression under conditions of variable temperature (between ambient and 600 °C) was analyzed. The results revealed that increases in the concentration of mining tailings and fine sand lead to an increase in the value of the maximum mechanical resistance, in contrast, the increase in the concentration of rice husk ash led to a reduction in the value of the maximum mechanical resistance. Furthermore, increases in test temperature, up to 500 °C, led to systematic increases in maximum mechanical strength. Finally, the geopolymeric concretes presented a brittle-ductile transition between 500 and 600 °C showing only a ductile behavior when tested at 600 °C and only brittle up to test temperatures of 500 °C.
Evaluation of the Thermic Efficiency of the Prototype at Scale of a Sustainable Housing that Uses Concrete with PET Fibers (CFP) and the Trombe System
Authors: Dueñas B , Soto W , Carrera E 
Published: February 2021

Abstract
In the last century, climate change has been one of the most notorious consequences of global warming. These changes are manifested through extremely warm or icy temperatures. Being the latter, the one that affects Andean populations in diverse parts of the world. In view of this, many researchers propose various techniques or methods to improve the conditions of habitability and thermic comfort to confront these cold temperatures. This study conducts an experimental investigation of the improvement of thermic efficiency that reaches a prototype of housing to include polyethylene terephthalate (PET), as a component of the concrete mixture in the structural elements. For this purpose, studies were reviewed that allowed selecting the most optimal considerations, with respect to the elaboration and inclusion of PET in the mixture. In addition, the proposed technique includes an adaptation and innovation of the trombe system in the roof, in order to optimize the thermic properties. The results in the present study show that this combination has allowed us to considerably improve the thermal efficiency properties in the prototype of the housing, which is an indicator of its performance when it is applied to real scale housing.
Assessment of a Real-life Concrete Bridge Structure using Vibration-based Damage Detection Method
Authors: Aasim Bashir Ahmad , Karimi Abdul Khaliq , Tomiyama Jun 
Published: February 2021

Abstract
Structural damage is usually presented in the form of decrease in stiffness resulting changes in the dynamic behavior of the structure, and natural frequency of the structure being one of the dynamic variables. A vibration-based damage detection method was employed to evaluate the structural health condition of a deteriorated bridge. The bridge has been closed for the traffic due to owing the extreme deteriorated health condition because of the immense existence of chloride ion in the airborne particles of the saline environment. This study presents, the comparison of natural frequencies of the year 2017 to that acquired in the year 2016 using vibration-based damage detection method. Even though the bridge was not exposed to the service load during the study period, yet, the results manifested decrement in natural frequencies revealing decline in structural stiffness in this period.
Estimation of Measurement Uncertainty of Factor Assays Using the Monte Carlo Simulation
Authors: Lim Yong Kwan , Kweon Oh Joo , Lee Mi-Kyung , Kim Hye Ryoun 
Published: February 2021

Abstract

Objectives
We aimed to quantify the measurement uncertainty (MU) for factor activities using the Monte Carlo simulation (MCS), which is a computational algorithm that simulates statistical sampling to obtain numerical results through complex mathematical calculations.

Methods
The uncertainties of factor V (FV), factor VIII (FVIII), and factor X (FX) were simulated with two coagulation testing systems: ACL TOP 750 CTS (Instrumentation Laboratory) and STA Compact (Diagnostica Stago).

Results
When the factor activities were 74% (FV), 68% (FVIII), and 89% (FX), the MUs were 3.5% (FV), 9.3% (VIII), and 2.8% (FX) for ACL TOP and 8.5% (FV), 18.2% (FVII), and 6.5% (FX) for STA Compact. MCS MUs were compared with MUs obtained from running actual samples (not simulated) using a method called the top-down approach. The MCS MU results were interchangeable with MUs from the top-down approach, except for FVIII from STA Compact.

Conclusions
The MCS procedure is well suited for the quantification of MUs for factor assays over the entire measurement range.
Bortezomib for treatment of anti–NMDA receptor encephalitis in a pediatric patient refractory to conventional therapy
Authors: Simmons Marroyln L , Perez Kimberly A 
Published: February 2021

Abstract

Purpose
The case of a pediatric patient with treatment refractory anti–N-methyl-d-aspartate (NMDA) receptor encephalitis treated with the plasma cell–depleting therapy bortezomib is reported.

Summary
A 5-year-old female presented to the hospital with a 1-week history of altered mental status, agitation, and possible seizure-like activity. She was admitted to the hospital for suspected meningitis or meningoencephalitis and an extensive workup was completed, including sending blood and cerebrospinal fluid (CSF) for testing for NMDA receptor antibodies. While test results were pending, the patient was treated initially with intravenous immunoglobulin (IVIG) for 4 days followed by high-dose methylprednisolone for 5 days. The patient’s serum and CSF studies were positive for NMDA receptor antibodies, confirming the diagnosis of anti–NMDA receptor encephalitis. She was then treated with plasmapheresis therapy every other day for 5 treatments, without any clinical improvement. The patient then received rituximab once weekly for 6 weeks. Three weeks after completion of rituximab therapy, the patient was started on her first cycle of bortezomib therapy. She received a total of 6 cycles, with improvement in her clinical status beginning with the third cycle. Upon completion of 6 cycles, the patient’s mental status and level of functioning had greatly improved. She was discharged to an inpatient rehabilitation facility and ultimately able to return home to her family.

Conclusion
A 5-year-old female with anti–NMDA receptor encephalitis was successfully treated with bortezomib after having shown no clinical improvement during treatment with IVIG, high-dose methylprednisolone, plasmapheresis, and rituximab.
Creating Synergies between Citizen Science and Indigenous and Local Knowledge
Authors: Tengö Maria , Austin Beau J , Danielsen Finn , Fernández-Llamazares Álvaro 
Published: February 2021

Abstract
Citizen science (CS) is receiving increasing attention as a conduit for Indigenous and local knowledge (ILK) in ecosystem stewardship and conservation. Drawing on field experience and scientific literature, we explore the connection between CS and ILK and demonstrate approaches for how CS can generate useful knowledge while at the same time strengthening ILK systems. CS invites laypersons to contribute observations, perspectives, and interpretations feeding into scientific knowledge systems. In contrast, ILK can be understood as knowledge systems in its own right, with practices and institutions to craft legitimate and useful knowledge. Such fundamental differences in how knowledge is generated, interpreted, and applied need to be acknowledged and understood for successful outcomes. Engaging with complementary knowledge systems using a multiple evidence base approach can improve the legitimacy of CS initiatives, strengthen collaborations through ethical and reciprocal relationships with ILK holders, and contribute to better stewardship of ecosystems.
Visions of the Common Good: Engelhardt’s Engagement with Catholic Social Teaching
Authors: Eberl Jason T 
Published: February 2021

AbstractIn this paper, I confront Engelhardt’s views—conceptualized as a cohesive moral perspective grounded in a combination of secular and Christian moral requirements—on two fronts. First, I critique his view of the moral demands of justice within a secular pluralistic society by showing how Thomistic natural law theory provides a content-full theory of human flourishing that is rationally articulable and defensible as a canonical vision of the good, even if it is not universally recognized as such. Second, I defend the principles of Roman Catholic social teaching (RCST) against Engelhardt’s objection that it constitutes a watered-down version of the Christian moral vision which opens the door to intolerable moral compromises. While I acknowledge that Engelhardt’s criticism of RCST is well-grounded in certain abusive compromises that have been made by some Catholic healthcare institutions, I contend that such abuses are not endemic to RCST and avoidance of them is practically feasible in contemporary secular pluralistic societies. My primary aim is to show how continued dialogue between Engelhardtian libertarians and more communitarian-inclined RCST proponents may constructively yield a vision of healthcare allocation that ensures succor for the least advantaged within an authentically Christian social ethic.
Conscientious Objection or an Internal Morality of Medicine?
Authors: Hershenov David 
Published: February 2021

AbstractDoctors, nurses, and pharmacists who refuse on grounds of conscience to participate in certain legal, expected, and standard practices have been accused of unprofessionally introducing their personal views into medicine. My first response is that they often are not engaging in conscientious objection because that involves invoking convictions external to those of the medical community. I contend that medicine, properly construed, is pathocentric, and so refusing to induce a pathology via abortion, contraception, euthanasia, etc., is actually being loyal to the internal morality of medicine. My second response is that even if such refusals are best considered conscientious objection, there is still no personal hijacking of medicine. Doctors refusing to induce pathologies need not refuse qua Christian, but can do so qua doctor. A pathocentric account of medicine provides a principled way of distinguishing conscientious objection from religious, idiosyncratic, and bigoted refusals. Patients’ refused pathology-inducing procedures are not medically harmed.
Development of an Ion-Pair Dispersive Liquid–Liquid Microextraction Method Based on a Ternary Deep Eutectic Solvent for Determination of Some Herbicide Residues in Edible Oil Samples
Authors: Torbati Mohammadali , Gonbari Milani Payam , Farajzadeh Mir Ali , Afshar Mogaddam Mohammad Reza 
Published: February 2021

Abstract
An ion-pair deep eutectic solvent (DES)-based dispersive liquid–liquid microextraction method was introduced and applied for the extraction of some acidic herbicides from edible oil samples prior to their determination by high performance liquid chromatography. First, a ternary DES composed of decanoic acid, dichloroacetic acid, and phosphocholine chloride is prepared under mild conditions. Then, the analytes are extracted into an alkaline solution from the oil samples by deprotonation of the herbicides. Afterward, the deprotonated analytes are extracted into the prepared DES with the aid of tri-butyl amine (as an ion-pair agent) in the presence of acetic acid (as a pH adjustment agent and dispersive solvent). The validation parameters indicated that the method has low limits of detection (0.09–0.72 ng mL−1) and quantification (0.30–2.3 ng mL−1), an acceptable percision (relative standard deviation ≤  9.0%) and high extraction recoveries (85–94%), and enrichment factors (566–626). The method was used in the analysis of 35 edible oil samples to assessment the studied analytes and the presence of haloxyfop was confirmed in three corn oils.
The Benefits and Harms of Antibiotic Prophylaxis for Urinary Tract Infection in Older Adults
Authors: Langford Bradley J , Brown Kevin A , Diong Christina , Marchand-Austin Alex , Adomako Kwaku , Saedi Arezou , Schwartz Kevin L , Johnstone Jennie , MacFadden Derek R , Matukas Larissa M , Patel Samir N , Garber Gary , Daneman Nick 
Published: February 2021

Abstract

Background
The role of antibiotics in preventing urinary tract infection (UTI) in older adults is unknown. We sought to quantify the benefits and risks of antibiotic prophylaxis among older adults.

Methods
We conducted a matched cohort study comparing older adults (≥66 years) receiving antibiotic prophylaxis, defined as antibiotic treatment for ≥30 days starting within 30 days of a positive culture, with patients with positive urine cultures who received antibiotic treatment but did not receive prophylaxis. We matched each prophylaxis recipient to 10 nonrecipients based on organism, number of positive cultures, and propensity score. Outcomes included (1) emergency department (ED) visit or hospitalization for UTI, sepsis, or bloodstream infection within 1 year; (2) acquisition of antibiotic resistance in urinary tract pathogens; and (3) antibiotic-related complications.

Results
Overall, 4.7% (151/3190) of UTI prophylaxis patients and 3.6% (n = 1092/30 542) of controls required an ED visit or hospitalization for UTI, sepsis, or bloodstream infection (hazard ratio [HR], 1.33; 95% confidence interval [CI], 1.12–1.57). Acquisition of antibiotic resistance to any urinary antibiotic (HR, 1.31; 95% CI, 1.18–1.44) and to the specific prophylaxis agent (HR, 2.01; 95% CI, 1.80–2.24) was higher in patients receiving prophylaxis. While the overall risk of antibiotic-related complications was similar between groups (HR, 1.08; 95% CI, .94–1.22), the risk of Clostridioidesdifficile and general medication adverse events was higher in prophylaxis recipients (HR [95% CI], 1.56 [1.05–2.23] and 1.62 [1.11–2.29], respectively).

Conclusions
Among older adults with UTI, the harms of long-term antibiotic prophylaxis may outweigh their benefits.
Effectiveness of the Recombinant Zoster Vaccine in Adults Aged 50 and Older in the United States: A Claims-Based Cohort Study
Authors: Sun Yuwei , Kim Eric , Kong Christina L , Arnold Benjamin F , Porco Travis C , Acharya Nisha R 
Published: February 2021

Abstract

Background
The recombinant zoster vaccine had over 90% efficacy in preventing herpes zoster in clinical trials. However, its effectiveness outside of a clinical trial setting has not been investigated. This study aimed to assess the effectiveness of the recombinant zoster vaccine in general practice.

Methods
A de-identified administrative claims database, the OptumLabs Data Warehouse, was used to conduct this retrospective cohort study to assess the effectiveness of the recombinant zoster vaccine against herpes zoster in nonimmunocompromised, vaccine age–eligible individuals enrolled in the database for ≥365 days.

Results
A total of 4 769 819 adults were included in this study, with 173 745 (3.6%) adults receiving 2 valid doses of the recombinant zoster vaccine. The incidence rate of herpes zoster was 258.8 (95% confidence interval [CI], 230.0–289.4) cases per 100 000 person-years in vaccinated persons compared with 893.1 (95% CI, 886.2–900.0) in unvaccinated persons. Recombinant zoster vaccine effectiveness was 85.5% (95% CI, 83.5–87.3%) overall, with an effectiveness of 86.8% (95% CI, 84.6–88.7%) in individuals 50 to 79 years old compared with 80.3% (95% CI, 75.1–84.3%) in individuals aged 80 and older. In patients with a history of live zoster vaccine within 5 years of study inclusion, vaccine effectiveness was 84.8% (95% CI, 75.3–90.7%).

Conclusions
Recombinant zoster vaccine effectiveness against herpes zoster was high in a real-world setting. Given the low vaccine coverage and high effectiveness, a major public health effort is needed to identify and address barriers to vaccination and increase immunization rates.