bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preferensi (Komunikasi Pemasaran dan E-Service Quality) Mahasiswa Manajemen Universitas Pamulang Terhadap Pemilihan Situs Belanja Online
Authors: Sholeh Achmad Nur , Budiyanto Arief 
Published: February 2021

The objectives of this study are : (1) To determine the effect of Marketing Communication on Online Purchase Site Selection Decisions, (2) To determine the effect of E-Service Quality on Online Purchase Site Selection Decisions and (3) To determine the effect of Marketing Communication and E -Service Quality on the Decision to Choose Online Purchase Sites collectively. Quantitative methods are used in this research. Data is taken from the results of a questionnaire sent via google form as well as observation and documentation. The number of respondents who were sampled was as many as 100 respondents with simple random sampling technique as a sampling technique. Data analysis assisted by SPSS 25.0 software. T (partial) and F (simultant) test results are proven to show a significant relationship between Marketing Communication, E-Service Quality and Student Decisions in Choosing E-Commerce.
Abstrak
Tujuan dari penelitian ini adalah : (1) Untuk mengetahui pengaruh Komunikasi Pemasaran terhadap Keputusan Pemilihan Situs Belanja Online, (2) Untuk mengetahui pengaruh E-Service Quality terhadap Keputusan Pemilihan Situs Situs Belanja Online dan (3) Untuk Untuk mengetahui pengaruh Komunikasi Pemasaran dan E-Service Quality terhadap Keputusan Pemilihan Situs Situs Belanja Online secara bersama - sama. Metode kuantitatif digunakan dalam penelitian ini. Data diambil dari hasil kuesioner yang dikirimkan melalui google form dan juga observasi serta dokumentasi. Jumlah responden yang dijadikan sampel adalah sebanyak 100 responden dengan tehnik simple random sampling sebagai tehnik pengambilan sampel. Analisis data bantuan piranti lunak SPSS 25.0. Hasil uji T (parsial) dan F (simultan) terbukti menunjukkan adanya hubungan yang signifikan antara Komunikasi Pemasaran, E-Kualitas Layanan terhadap Keputusan Mahasiswa dalam Pemilihan Situs Belanja Online.
Kata Kunci : Keputusan Pemilihan Konsumen, E-Kualitas Layanan, Komunikasi Pemasaran, Situs Jual Beli Online
THE EFFECTIVENESS OF AL-QURâ€™AN MURROTAL THERAPY ON REDUCING PAIN AMONG POSTOPERATIVE PATIENTS: A SYSTEMATIC REVIEW
Authors: Permana Bhakti , Nurhayati Nunung , Amelia Citra Nurintan , Lindayani Linlin 
Published: February 2021

Nyeri merupakan suatu kondisi yang lebih dari satu sensasi yang disebabkan oleh stimulus tertentu. Intensitas bervariasi dari rasa nyeri ringan hingga nyeri berat, tetapi menurun sejalan dengan proses penyembuhan. Manajemen nyeri pada pasien pasca operasi sangat penting baik terapi farmakologi dan nonfarmakologi. Metode farmakologi yang digunakan sebagai manajemen nyeri adalah pemberian analgesic anti nyeri, yang dibagi menjadi dua kelompok: analgesik dan non-narkotik. Nonfarmakologi menyajikan beberapa bentuk terapi musik dan distraksi. Musik adalah kumpulan bunyi yang ditetapkan untuk menghasilkan ritme atau nyanyian, yang dihasilkan dari alat-alat musik yang dapat menghasilkan ritme. Terapi murottal Qurâ€™an adalah terapi mendengarkan al-qurâ€™an yang merupakan terapi keagamaan dimana seseorang mendengarkan ayat-ayat Al-Qurâ€™an. Penulisan Karya Tulis Ilmiah ini menggunakan metode tinjauan sistematis terhadap literature yang ada, untuk mengevaluasi respon subjektif pasien setelah menerapkan terapi murrotal terhadap penurunan nyeri pasca operasi. Hasil dari penelitian literature review iniÂ terbukti bahwa terapi murrotal Al-Qurâ€™an efektif untuk menurunkan nyeri terhadap pasien pasca operasi. Terapi murrotal Al-Qurâ€™an dapat menggunakan surah yang terkandung dalam Al-Qurâ€™an dan melakukannya selama 15-20 menit.
SURVEI KEPADATAN JENTIK NYAMUK AEDES AEGYPTI PADA PENAMPUNGAN AIR DALAM RUMAH DAN IMPLIKASINYA TERHADAP KEPERAWATAN KOMUNITAS
Authors: Khotafiatun Khotafiatun , Sugiharto Sh , Natalya Wiwiek 
Published: February 2021

Nyamuk Aedes aegypti merupakan vektor penyakit demam berdarah dengue. Kepadatan nyamuk Aedes aegypti sebagai indikator penularan dan penyebaran demam berdarah dengue dapat dilihat dari tempat perindukkannya yaitu penampungan air. Penelitian ini bertujuan untuk mengetahui gambaran kepadatan jentik nyamuk Aedes aegypti pada penampungan air dalam rumah di Wilayah Kerja Puskesmas Tirto II Kabupaten Pekalongan. Desain penelitian ini menggunakan desain deskriptif. Tehnik sampling menggunakan tehnik Cluster Sampling dengan jumlah responden 274 unit rumah. Untuk memantau jentik nyamuk menggunakan checklist pemeriksaan jentik berkala dari DepKes RI. Data dianalisa berdasarkan frekuensi dan prosentase. Hasil penelitian menunjukkan nilai House Index sebesar 32,1%, Container Index 13,7%, Breteau IndexÂ 42,7% dan Angka Bebas Jentik 68%. Indiator-indikator tersebut menunjukkan Desa Jeruksari termasuk dalam kategori risiko tinggi penularan penyakit Demam Berdarah Dengue. Sehingga disarankan bagi perawat komunitas untuk lebih menggiatkan penyuluhan kesehatan dan memberdayakan masyarakat serta kader kesehatan dalam kegiatan pemberantasan sarang nyamuk 3M-Plus.
Latihan Berjalan Untuk Menurunkan Tekanan Darah pada Penderita Hipertensi
Authors: Parwata Ni Made Ridla , Tasnim Tasnim 
Published: February 2021

World Health Organization (WHO) (2015), menunjukkan bahwa sekitar 1,13 miliar orang di dunia menderita hipertensi. Diperkirakan pada tahun 2025 akan ada 1,5 Miliar orang yang terkena hipertensi, dan diperkirakan setiap tahunnya 10,44 juta orang meninggal akibat hipertensi dan komplikasinya. Sebanyak 34,1% penduduk Indonesia berumur >18 tahun menderita hipertensi. Sulawesi Tengah pada tahun 2017 dari 76.911 jiwa penduduk usia ≥18 tahun, sebesar 3.436 yang diukur tekanan darahnya terdapat 2.711 jiwa yang menderita Hipertensi (78,9%). Prevalensi hipertensi di kabupaten Poso pada tahun 2017 sebesar 12,85%. Metode yang digunakan dalam pengabdian masyarakat ini meliputi pemeriksaan tanda-tanda vital, kadar kolestrol darah dan mengecek status pernapasan (dispnea atau nyeri dada), ceramah dan diskusi, demonstrasi dan pelaksanaan Latihan Berjalan. Hasil kegiatan ini, dari 15 peserta ada 10 peserta yang mengalami penurunan tekanan dan 5 peserta tidak mengalami perubahan tekanan darah sistol. Ada 7 orang peserta yang mengalami penurunan tekanan darah diastole dan 8 orang peserta memiliki tekanan darah diastole yang sama sebelum dan sesudah latihan berjalan. Kesimpulan: Latihan berjalan dapat menurunkan tekanan darah pada penderita hipertensi. Saran: Masyarakat terutama penderita hipertensi agar dapat melakukan latihan berjalan sebagai salah satu alternatif yang mudah, murah, efektif dan efisien untuk menurunkan tekanan darah.
Recombinant Adiponectin Induces the Production of Pro-Inflammatory Chemokines and Cytokines in Circulating Mononuclear Cells and Fibroblast-Like Synoviocytes From Non-Inflamed Subjects
Authors: Zhang Yuan , Aldridge Jonathan , Vasileiadis Georgios K. , Edebo Helena , Ekwall Anna-Karin H. , Lundell Anna-Carin , Rudin Anna , Maglio Cristina 
Published: February 2021

Adiponectin is an adipokine with a modulatory role in metabolism and exerting both anti- and pro-inflammatory effects. Levels of adiponectin are increased in serum and synovial fluid from patients with rheumatoid arthritis (RA). Adiponectin is able to stimulate the production of different pro-inflammatory factors from peripheral blood mononuclear cells (PBMCs) and fibroblast-like synoviocytes (FLS) from subjects with established RA. As increased circulating adiponectin levels are a risk factor for future development of RA in subjects with obesity, we hypothesize that adiponectin is implicated in the development of RA at an early stage by initiating the pro-inflammatory processes associated with the disease pathogenesis. Therefore, we aimed to determine if adiponectin is able to induce pro-inflammatory responses in cells involved in the pathogenesis of RA, but collected from subjects without any known inflammatory disease. PBMCs and FLS were obtained from non-inflamed subjects and stimulated with 5 μg/ml human recombinant adiponectin. Supernatants collected after 48 h were analyzed for the production of 13 chemokines and 12 cytokines using multiplex assay and ELISA. Adiponectin significantly stimulated the production of CXCL1, CXCL5, and interleukin (IL)-6 in both PBMCs and FLS, whereas it induced CCL20, CCL4, CCL3, CCL17, tumor necrosis factor (TNF), granulocyte-macrophage colony-stimulating factor and IL-10 only in PBMCs, and CXCL8, CXCL10, CCL5, CCL11, and CCL2 only in FLS. Pre-stimulation with TNF of FLS from non-inflamed subjects did not significantly enhance the release of most pro-inflammatory factors compared to adiponectin alone. Our findings indicate that PBMCs and FLS from non-inflamed subjects react to adiponectin stimulation with the secretion of several pro-inflammatory chemokines and cytokines. These results suggest that adiponectin is able to initiate pro-inflammatory responses in cells from non-inflamed subjects and support the hypothesis that adiponectin is implicated in the early phases of RA pathogenesis.
Impact of Intermittent Fasting on Lipid Profile–A Quasi-Randomized Clinical Trial
Authors: Ahmed Naseer , Farooq Javeria , Siddiqi Hasan Salman , Meo Sultan Ayoub , Kulsoom Bibi , Laghari Abid H. , Jamshed Humaira , Pasha Farooq 
Published: February 2021

Background: Sub-optimal HDL is a prognostic marker of cardiovascular disease. South Asia has a high prevalence of sub-optimal HDL compared to other parts of the world. Intermittent fasting (IF) is a type of energy restriction which may improve serum HDL and other lipids thereby reducing the risk of cardiovascular diseases.Objective: The aim of the study was to evaluate the effect of IF on lipid profile and HDL-cholesterol in a sample of South Asian adults.Methods: A 6-week quasi-experimental (non-randomized) clinical trial was conducted on participants with low HDL (&lt; 40 mg/dl for men and &lt; 50 mg/dl for women). Participants of the control group were recommended not to change their diet. The intervention group was recommended to fast for ~12 h during day time, three times per week for 6 weeks. Pulse rate, blood pressure, body weight, waist circumference, serum lipid profile, and blood glucose levels were measured at baseline and after 6 weeks.Result: A total of 40 participants were enrolled in the study (N = 20 in each group), while 35 (20 control and 15 intervention) completed the trial and were included in data analysis of the study. Body measurements, including body weight, BMI and waist circumference, showed significant interaction effects (p's &lt; 0.001), indicating that there were larger reductions in the IF group than in the control group. Significant interaction effects were also observed for total (p = 0.033), HDL (p = 0.0001), and LDL cholesterol (p = 0.010) with larger improvements in the IF group.Conclusion: This study suggests that intermittent fasting may protect cardiovascular health by improving the lipid profile and raising the sub-optimal HDL. Intermittent fasting may be adopted as a lifestyle intervention for the prevention, management and treatment of cardiovascular disorders.Clinical Trial Registration: NCT03805776, registered on January 16, 2019, https://clinicaltrials.gov/ct2/show/NCT03805776
Expression of Human Epidermal Growth Factor Receptor-2 Status and Programmed Cell Death Protein-1 Ligand Is Associated With Prognosis in Gastric Cancer
Authors: Lv Huifang , Zhang Junling , Sun Keran , Nie Caiyun , Chen Beibei , Wang Jianzheng , Xu Weifeng , Wang Saiqi , Liu Yingjun , Chen Xiaobing 
Published: February 2021

BackgroundPD-L1 and HER-2 are routine biomarkers for gastric cancer (GC). However, little research has been done to investigate the correlation among PD-L1, HER-2, immune microenvironment, and clinical features in GC.MethodsBetween January 2013 and May 2020, a total of 120 GC patients treated with chemotherapy were admitted to Henan Tumor Hospital. We retrospectively identified PD-L1, HER-2 level before chemotherapy and abstracted clinicopathologic features and treatment outcomes. Univariate and multivariate survival analyses were performed to assess the relationship between PD-L1/HER-2 levels and progression-free survival (PFS). The mRNA and tumor microenvironment of 343 patients with GC from The Cancer Genome Atlas (TCGA) were used to explore the underlying mechanism.ResultsWe retrospectively analyzed 120 patients with gastric cancer, including 17 patients with HER-2 positive and 103 patients with HER-2 negative GC. The results showed that the expression of PD-L1 was closely correlated with HER-2 (P = 0.015). Patients with PD-L1/HER-2 positive obtained lower PFS compared to PD-L1/HER-2 negative (mPFS: 6.4 vs. 11.1 months, P = 0.014, mPFS: 5.3 vs. 11.1 months, P = 0.002, respectively), and the PD-L1 negative and HER-2 negative had the best PFS than other groups (P = 0.0008). In a multivariate model, PD-L1 status, HER-2 status, tumor location, and tumor differentiation remained independent prognostic indicators for PFS (P &lt; 0.05). The results of database further analysis showed that the proportion of PD-L1+/CD8A+ in HER-2 negative patients was higher than that in HER-2 positive patients (37.6 vs 20.3%), while PD-L1−/CD8A− was significantly higher in HER-2 positive patients than HER-2 negative patients (57.8 vs. 28.8%). In addition, it showed that not only CD4+T cells, macrophages, and CD8+T cells, but also the associated inflammatory pathways such as IFN-γ/STAT1 were associated with HER-2.ConclusionHER-2 status could predict the efficacy of immune checkpoint inhibitors, and HER-2 status combined with PD-L1 level could predict the prognosis of GC patients.
Faith-Based Coping Among Arabic-Speaking Refugees Seeking Mental Health Services in Berlin, Germany: An Exploratory Qualitative Study
Authors: Rayes Diana , Karnouk Carine , Churbaji Dana , Walther Lena , Bajbouj Malek 
Published: February 2021

Background: The benefits of faith-based coping or using religious and spiritual beliefs as a stabilizing force for interpreting stressful or distressing events are largely unexplored among the exodus of Arabic-speaking refugee populations from Muslim-majority countries, particularly those resettled in Europe. The present study aimed to explore the manifestation of faith-based coping strategies among Arabic-speaking refugee adults seeking mental healthcare services in Berlin, Germany and explore how favorable faith-based coping strategies can be optimized from a mental health service-delivery and broader integration perspective.Methods: A total of 17 qualitative interviews were conducted with Arabic-speaking refugee adults (six females, 11 males) seeking mental health services at the Charité Universitaetsmedizin in Berlin. Research questions aimed to solicit comprehensive perspectives from refugee adults on their mental health, with an emphasis on faith-based coping, and how this facilitated or impeded their integration into German society. Interview transcripts were translated to English from Arabic and analyzed using MAXQDA (2018) to highlight thematic patterns using a grounded theory approach.Results: Findings were structured into four themes, including: (I) faith-based coping methods during flight, (II) changes in faith practices upon arrival, (III) faith-based coping methods to address distress during integration, and (IV) advice for German mental healthcare providers. Participants who demonstrated a stronger commitment to faith were more likely to utilize faith-based coping strategies when seeking mental health services and facing the challenges of displacement and integration. Examples of faith-based coping included prayer, supplication, reciting scripture, and seeking help from a local religious leader.Conclusion: The findings suggest how faith and faith practices play a significant role in the mental health and integration of refugee populations in Germany and provide insight on how mental healthcare can be delivered in a culturally-sensitive manner, providing alternatives to the social, cultural, and linguistic barriers posed by the German health system. These findings are particularly relevant for mental health professionals, non-governmental organizations, and humanitarian aid agencies providing mental healthcare to Arabic-speaking populations recently resettled in Western contexts.
Methaemoglobinaemia Can Complicate Normothermic Machine Perfusion of Human Livers
Authors: Tingle Samuel J. , Ibrahim Ibrahim , Thompson Emily R. , Bates Lucy , Sivaharan Ashwin , Bury Yvonne , Figuereido Rodrigo , Wilson Colin 
Published: February 2021

Background: Although liver normothermic machine perfusion is increasingly used clinically, there are few reports of complications or adverse events. Many centers perform liver NMP to viability test suboptimal grafts, often for prolonged periods. In addition, several researchers are investigating NMP as a drug delivery platform, which usually necessitates prolonged perfusion of otherwise non-viable liver grafts. We describe two instances of methaemoglobinaemia during NMP of suboptimal livers.Methods: The NMP of eight human livers rejected for transplantation is described. Methaemoglobinaeima developed in two; one perfused using generic Medtronic™ perfusion equipment and one using the OrganOx Metra®.Results: The first liver (53 years DBD) developed methaemoglobinaemia (metHb = 2.4%) after 13 h of NMP, increasing to metHb = 19% at 16 h. Another liver (45 years DBD) developed methaemoglobinaemia at 25 h (metHb = 2.8%), which increased to metHb = 28.2% at 38 h. Development of methaemoglobinaemia was associated with large reductions in oxygen delivery and oxygen extraction. Both livers were steatotic and showed several suboptimal features on viability testing. Delivery of methylene blue failed to reverse the methaemoglobinaemia. Compared to a matched cohort of steatotic organs, livers which developed methaemoglobinaemia showed significantly higher levels of hemolysis at 12 h (prior to development of methaemoglobinaemia).Conclusions: Methaemglobinaemia is a complication of NMP of suboptimal liver grafts, not limited to a single machine or perfusion protocol. It can occur within 13 h (a timepoint frequently surpassed when NMP is used clinically) and renders further perfusion futile. Therefore, metHb should be monitored during NMP visually and using blood gas analysis.
PENSAMENTO COMPUTACIONAL NA APRENDIZAGEM MATEMÁTICA EDUCACIONAL
Authors: Corvalão Fabio Mello 
Published: February 2021

A lista de conhecimentos e habilidades necessária para o pleno exercício da cidadania no século XXI é extensa, incluindo o pensamento computacional, o qual pode apoiar e relacionar-se com outras áreas, pois os conceitos de pensamento computacional aliados a sua proposta fornecem métodos para a resolução de problemas , em especial na matemática, onde esses princípios da computação podem ser utilizados sob a perspectiva de desenvolvimento cognitivo dos alunos das séries iniciais, como forma de organização do pensamento, das ideias e das propostas de solução. Dentro desse contexto, de um lado os conceitos do pensamento computacional e do outro lado as competências necessárias aos alunos de matemática das séries iniciais, e tendo como referência os Parâmetros Curriculares Nacionais, No intuito de disseminar o pensamento computacional na educação básica, diversas ações têm sido realizadas a nivel de computação , como etapas do pensamento computacional , a relação do pensamento computacional com a robotica , a programação algoritmica computacional e a convenção interdisciplinar do pensamento computacional no cotidiano
ДОСЛІДЖЕННЯ ВЛАСТИВОСТЕЙ НАНОПОРИСТОГО ВУГЛЕЦЮ, ОТРИМАНОГО З КАРБІДІВ РІЗНОЇ БУДОВИ
Authors: Roslyk Iryna , Zahorodna Veronica 
Published: February 2021

Мета - визначення зв'язку між початковою структурою карбіду та пористою структурою синтезованого з нього вуглецю, а саме розмірами пор, розподілом пор за розмірами та величиною питомої поверхні. Методика. Нанопористий вуглець одержували високотемпературною обробкою порошків карбідів з різною будовою потоком хлору на експериментальній установці проточного типу. Визначення питомої поверхні та розміру пор виконували на автоматичному обладнанні (Quantachrome, США) з комп’ютерним керуванням та обробкою даних. Для визначення питомої поверхні застосовували метод Брунауера-Еммета-Теллера (БЕТ). Пористу структуру вуглецю, а саме об’єм пор та їх розподіл за розмірами, було визначено на підставі функціональної теорії нелокальної щільності (NLDFT) з застосуванням програмного забезпечення. Результати. Експериментально встановлено, що високопористий вуглець з розподілом розмірів пор в вузькому інтервалі від 0,5 до 2 нм можна отримати з карбідів, що мають кубічну гратку. Самий високий об’єм мікропор та найменший середній розмір пор спостерігається у вуглецю, що отриманий з карбіду титану з гранецентрованою кубічною ґраткою. Також у нього достатньо висока питома поверхня 1247 м2/г. Вуглець, синтезований з карбіду заліза Fe3C з ромбічною ґраткою, має найменший об’єм мікропор та самий широкий діапазон розподілу пор за розмірами (від 0,8 до 20 нм).Наукова новизна. Вперше встановлено що використання карбідів з кубічною граткою забезпечує отримання нанопористого вуглецю з контрольованими розмірами пор у межах від 0,5 до 2 нм та достатньо високою питомою поверхнею. Практична цінність. Результати роботи можуть бути використані для синтезу вуглецю для виготовлення електродів суперконденсаторів.
ДОСЛIДЖЕННЯ СТРУКТУРИ ТА ВЛАСТИВОСТЕЙ НИЗЬКОЛЕГОВАНОЇ МАЛОВУГЛЕЦЕВОЇ СТАЛI З ФЕРИТО-БЕЙНIТНОЮ СТРУКТУРОЮ ПIСЛЯ ТЕРМIЧНОГО ЗМIЦНЕННЯ ТА НАСТУПНОГО ВIДПУСКУ
Authors: Deineko Leonid , Borisenko Andrei , Taranenko Andrei , Zaytseva Tatyana , Romanova Natalia 
Published: February 2021

Мета – встановлення закономірностей в процесах структуроутворення в маловуглецевих низьколегованих сталях з ферито-бейнітною структурою в залежності від параметрів термічної обробки та їх вплив на властивості з’єднувальних деталей трубопроводів.Методика. Під час виконання дослідження використано: методи випробувань металу на розтяг, ударний вигин зразків Шарпі та Менаже при різних температурах, світлову та растрову металографію, рентгеноструктурний аналіз для дослідження макро-, мікро- та тонкої структури, топографії зламів зразків з маловуглецевої низьколегованої сталі 15ХСНД з ферито-бейнітною структурою після різних режимів термічної обробки.Результати. Встановлені закономірності впливу параметрів термічної обробки на структуру, механічні властивості та топографію зламів ударних зразків сталі 15ХСНД з ферито-бейнітною структурою.Наукова новизна. Результати досліджень дозволили вперше встановити залежність процесів структуроутворення в маловуглецевих низьколегованих сталях від параметрів охолодного середовища, способу термічного зміцнення та наступних параметрів відпуску, їх вплив на зміну механічних властивостей металу, що підтверджується отриманням низки патентів на розроблені технічні рішення.Практична цінність. Отримані результати досліджень дозволили створити та впровадити параметри промислової технології об’ємної термічної обробки штампозварних з’єднувальних деталей трубопроводів із товщиною стінки до 100 мм та конструктивно-технологічні параметри гартівного обладнання.