bluuebunny/crossref_metadata_2025_split huggingface dataset:
DIABETOGENIC EFFECT OF STATINS: MOLECULAR MECHANISMS
Authors: Arı Nuray 
Published: July 2021

Statins, HMG CoA inhibitors, are potent hypolipidemic drugs.They are used for the prevention of cardiovascular diseases and some of the most commonly used drugs worldwide. Long term statin therapy can cause a modest increase in new-onset diabetes risk, and there is great interest in the mechanisms for this adverse effect. Main proposed mechanisms are increased insulin resistance and some defects in insulin secretion. Many factors can affect the risk including pre-existing diabetic risk, older age and potency of statin. But clearly, the benefits of these drugs in preventing cardiovascular disease outweigh the potential risk of diabetes.The aim of this review is to give underlying pathomechanisms and clinical relevance of diabetogenic effect of statins.

Peer Review History:
Received: 18 May 2021; Revised: 24 June; Accepted: 29 June, Available online: 15 July 2021
Academic Editor: Dr. Ali Abdullah Al-yahawi, Al-Razi university, Department of Pharmacy, Yemen, alyahawipharm@yahoo.com
UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.
Received file: Reviewer's Comments:
Average Peer review marks at initial stage: 5.0/10
Average Peer review marks at publication stage: 7.5/10
Reviewer(s) detail:
Dr. Salfarina Ramli, Department of Pharmacology and Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Teknologi MARA, 42300 Puncak Alam, Selangor, Malaysia. salfarina2892@uitm.edu.my
Dr. George Zhu, Tehran University of Medical Sciences, Tehran, Iran, sansan4240732@163.com
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RESEARCH, DEVELOPMENT AND TECHNOLOGY TRANSFER FOR INDUSTRIAL SUSTAINABILITY
Authors: KOCA Mehmet , DURGUN Meltem Ezgi , YAPAR Evren ALGIN 
Published: July 2021

Industrial development and continuity, which are indispensable for countries, depend on sustainability, which can be defined as Permanent Capability. In the basic steps of industrial sustainability, there are social, economic, and environmental factors. ISO 14001, 14004, 14005, and26000 regarding sustainability are important standards in this field. Research & Development and Technology Transfer are among the main factors that foster industrial development and continuity. Research & Development has three basic steps; it includes basic research, applied research, and experimental development, and its most important output is innovation. The industrial application of innovation or its transfer is possible with Technology Transfer, and this systematic process consists of five steps: providing the most suitable technology source to determine the most suitable option, selecting the optimum technology, having the necessary equipment and license, transferring knowledge and experience, and ensuring maximum benefit. Training and measurements are required to manage the process and for the internalization of the transferred technology. In this context, this review provides a basic and brief view of Research & Development, Technology Transfer, and Sustainability concepts and interactions, which are critical for the pharmaceutical industry.

Peer Review History:
Received: 1 May 2021; Revised: 12 June; Accepted: 27 June, Available online: 15 July 2021
Academic Editor: Dr. Ali Abdullah Al-yahawi, Al-Razi university, Department of Pharmacy, Yemen, alyahawipharm@yahoo.com
UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.
Received file: Reviewer's Comments:
Average Peer review marks at initial stage: 6.5/10
Average Peer review marks at publication stage: 7.5/10
Reviewer(s) detail:
Dr. Govind Vyas, Compliance & Regulatory Officer Inva-Tech Pharmaceuticals LLC, New-Jersey, USA, govindvyas03@gmail.com
Dr. Mohammad Bayan, Faculty of Pharmacy, Philadelphia University, P.O. Box: 1 Philadelphia University 19392 Jordan, mbayan01@qub.ac
The Endophytic Actinobacterial Toxicity Test of Ginger (Zingiber officinale Roscoe) Used The BSLT (Brine Shrimp Lethality Test) Method
Authors: Rahayu Sri , Fitri Lenni , Ismail Yulia Sari 
Published: July 2021

Abstract: Cancer is the biggest cause of death in Indonesia. Cancer treatment efforts have been made but it could harm cancer patients. It is necessary to find another alternative from nature as an anticancer. This study aims to see the ability of endophytic actinobacterial isolates from ginger (Zingiber officinale) as an anticancer tested using the BSLT method (Brine Shrimp Lethality Test) by calculating the values of LC50 and LT50. The best value isolates from the BSLT method, then tested using phytochemical ethanol extract. The highest toxicity value was found in AJ2 isolates. LC50 and LT50 values of AJ2 isolates were 309.358 µg/ml and 11.879 hours. Phytochemical results of ethanol extract of AJ2 isolates were detected containing steroids, terpenoids, phenols, tannins, flavonoids, alkaloids, and saponins. AJ2 isolates which derived from ginger endophytic actinobacteria have potential as an anticancer because they have high toxic values that rised rapidly.Abstrak: Kanker menjadi penyebab kematian terbesar di Indonesia. Upaya pengobatan kanker sudah dilakukan namun memberikan dampak negatif bagi penderita kanker. Perlu dilakukan penemuan alternatif lain berasal dari alam sebagai antikanker. Penelitian ini bertujuan untuk melihat kemampuan isolat aktinobakteri endofit asal jahe (Zingiber officinale) sebagai antikanker. 7 isolat aktinobakteri endofit jahe diuji menggunakan metode BSLT (Brine Shrimp Lethality Test) dengan menghitung nilai LC50 dan LT50. Isolat nilai terbaik dari metode BSLT, selanjutnya diuji menggunakan fitokimia ekstrak etanol. Nilai toksisitas tertinggi terdapat pada isolat AJ2. Nilai LC50 dan LT50 isolat AJ2 adalah 309,358 µg/ml dan 11,879 jam. Hasil fitokimia ekstrak etanol isolat AJ2 terdeteksi mengandung steroid, terpenoid, fenol, tanin, flavonoid, alkaloid dan saponin. Isolat AJ2 yang berasal dari actinobacteria endofit jahe berpotensi sebagai antikanker karena memiliki nilai toksik yang tinggi dalam waktu singkat.
Development of Kinetic Models For Biogas Production From Tofu Liquid Waste
Authors: Shitophyta Lukhi Mulia , Salsabila Anisa , Anggraini Firanita , Jamilatun Siti 
Published: July 2021

Abstract: Biogas promises bioenergy to be developed as a renewable fuel to reduce the fossil energy crisis. Biogas raw material can be derived from tofu liquid waste. Biogas is processed by anaerobic digestion. This study aimed to develop a simulation of the kinetic model variations of biogas production from tofu liquid waste. The results showed that the ascending limb of the exponential equation had a greater coefficient (R2 = 1) than the ascending limb of the linear equation (R2 = 0.9574). The descending limb of the linear equation had a better coefficient (R2 = 0.9574) than the descending limb of the exponential equation (R2 = 0.95). The Gaussian model had the greatest R2 of 0.9937. Logistic growth had the greatest coefficient (R2 = 0.9951) compared to modified Gompertz (R2 = 0.9817) and exponential rise to maximum (R2 = 0.9852) in the simulation of cumulative biogas production. The fit model for kinetic biogas production from tofu liquid waste is Gaussian Model.Abstrak: Biogas merupakan salah satu bioenergi yang menjanjikan untuk dikembangkan dalam mengurangi krisis energi fosil. Bahan baku biogas dapat berasal dari limbah cair tahu yang diolah secara anaerobic digestion. Penelitian ini bertujuan untuk mengembangkan variasi model simulasi kinetika produksi biogas dari limbah cair tahu. Hasil penelitian menunjukkan bahwa persamaan eksponensial untuk grafik kenaikan memilki koefisien yang lebih besar (R2 = 1) dibandingkan grafik kenaikan dengan persamaan linier (R2 = 0,9574). Grafik penurunan pada persamaan linier memiliki nilai koefisien lebih besar (R2 = 0,9574) dibandingkan grafik penurunan pada persamaan eksponensial (R2 = 0,95). Model Gaussian menghasilkan nilai koefisien tertinggi R2 = 0,9937. Logistic growth menghasilkan nilai R2 terbesar (0,9951) dibandingkan modified Gompertz (R2 = 0,9817) dan exponential rise to maximum (R2 = 0,9852) pada simulasi produksi biogas kumulatif. Model yang paling cocok untuk kinetika produksi biogas dari limbah cair adalah model Gaussian.
Perlindungan Dan Kemanfaatan Hukum Terhadap Putusan Itsbat Nikah Di Mahkamah Syar’iyyah Bireun (Analisis Putusan Perkara No. 82/Pdt.P/2019/Ms-Br)
Authors: Filzah Nadhilah 
Published: July 2021

Pencatatan nikah bersifat mutlak dimiliki oleh pasangan dan menjadi syarat administratif. Pemerintah memberikan alternatif untuk perkawinan yang tidak dicatatkan di KUA yaitu melakukan istbat nikah. Menggunakan pendekatan yuridis normatif, menyimpulkan masih ada masyarakat yang menikah dan tidak dicatatkan dengan berbagai alasan. Penulis membahas mengenai dua permasalahan. Pertama, terkait perlindungan hukum serta kemanfaatan hukum yang didapatkan dengan melakukan istbat nikah, Kedua, menganalisis Terhadap Putusan Itsbat Nikah di Mahkamah Syar’iyyah Bireun dengan Putusan Perkara No. 82/Pdt.P/2019/MS-BR. Hasil kajian ditemukan bahwa hal yang cacat dimata hukum, maka adanya istbat perlindungan hukum dan kemanfaatan segala hak masyarakat sebagai bagian dari warga negara wajib untuk dilindungi dalam segala permasalahan keperdataan. Dari analisis yang diuraikan, maka, ada beberapa faktor yang menyebabkan perkawinan tidak dicatatkan salah satunya adalah kurangnya pengetahuan sebagian golongan masyarakat, membayar biaya nikah atau akses tempat yang tidak dapat dijangkau dan faktor lain tidak bertentangan dengan ketentuan hukum Islam dan positif.
Analisis Hubungan antara Gratitude Dengan Sense of School Belonging Pada Mahasiswa Karesidenan Madiun
Authors: Dani Robik Anwar , Aryono Marcella Mariska , Cahyadi Andi 
Published: July 2021

Abstrak : Mahasiswa terkadang berperilaku seperti kurang antusias dengan kegiatan kemahasiswaan yang diadakan oleh universitas, sering tidak menghadiri perkuliahan tanpa alasan, dan kadang berperilaku yang tidak sesuai dengan nilai-nilai organisasi. Hal ini dapat mengindikasikan bahwa terdapat masalah dengan rasa memiliki mahasiswa terhadap sekolah (sense of school belonging). Rasa syukur (gratitude) mahasiswa terhadap universitas dapat menjadi faktor yang mempengaruhi rasa memiliki mahasiswa terhadap universitas. Oleh karena itu, penelitian ini bertujuan untuk mengetahui hubungan gratitude dan sense of school belonging. Metode penelitian yang digunakan dalam penelitian ini adalah metode kuantitatif korelasional. Subjek penelitian ini adalah 254 mahasiswa yang sedang menempuh pendidikan di berbagai perguruan tinggi di wilayah Madiun. Pengumpulan data dilakukan dengan menggunakan Tes Rasa Syukur dan Apresiasi (GRAT) Bentuk Pendek dan Skala Kepekaan Psikologis Sekolah (PSSM). Hasil penelitian ini dianalisis menggunakan analisis regresi linear sederhana. Analisis data menunjukkan bahwa besar koefisien regresi standar b=0,323 dengan signifikansi p<0,05. Variabel gratitude terbukti berhubungan dan dapat memprediksi variabel sense of school belonging. Implikasi hasil penelitian ini dibahas lebih lanjut oleh peneliti.Kata kunci: Sense of school belonging, gratitude, mahasiswa Abstract: Students sometimes behave like they are not enthusiastic about student activities held by the university, absent in classes without reason, and their behavior do not fit the organizational values. These show that there is might a problem with the students' sense of school belonging. The students’ gratitude regarding their university can be a factor that affects the students' sense of school belonging. Therefore, this study aims to determine the relationship between gratitude and sense of school belonging. The research method used in this research is quantitative method. The subjects of this research were 254 students who are studying in different university in the Madiun Region. The data was collected using the Gratitude Resentment and Appreciation Test (GRAT) Short Form and the Psychological Sense of School Membership Scale (PSSM). This study was analyzed using simple linear regression analysis. Data analysis showed that the standardized regression coefficient b=0.323 with a significance p<0.05. Gratitude is proven to be related and can predict the sense of school belonging. The implications of the results of this study are discussed further by the researcher.Keywords: Sense of school belonging; gratitude; college students
Rota-type operators on 3-dimensional nilpotent associative algebras
Authors: Abdujabborov N.G. , Karimjanov I.A. , Kodirova M.A. 
Published: July 2021

Abstract
We give the description of Rota–Baxter operators, Reynolds operators, Nijenhuis operators and average operators on 3-dimensional nilpotent associative algebras over ℂ.
RF energy harvesting using a compact rectenna with an antenna array at 2.45 GHz for IoT applications
Authors: Pramono Subuh , Shidiq Dwiki Dimas , Ibrahim Muhammad Hamka , Adriyanto Feri , Hikmaturokhman Alfin 
Published: July 2021

Abstract
This work addresses the design, fabrication, and implementation of an RF energy harvester 2.45 GHz using a compact rectenna. Our proposed rectenna focuses on development of an antenna array and rectifier circuit. The proposed rectenna is fabricated using FR4 substrate with its overall size of 12.24 cm × 18.17 cm with a thickness of 1.6 mm. The measured results show that a 10 dB bandwidth covering in 2374-2549 MHz (175 MHz) with center frequency 2415 MHz at S
11 of −18.2 dB. There is a bandwidth enhancement of 57.6% compared to the single antenna. Gaining of the antenna array is 6 dB that is double a single antenna gain. Spatial diversity technique in antenna array yields a bigger antenna gain thereby increasing the received power level. Experimental measurements are carried out that the rectenna is placed indoor (LOS) at 5 m and outdoor (NLOS) at 15 m. Furthermore, we also explore the rectifier circuit that to maximize the output voltage. The received RF power that transmitted from WiFi router is −55 dBm (0.15 nW/cm2) at 5 m and −59 dBm (0.06 nW/cm2) at 15 m, respectively. The output voltages are achieved that 1092.5 mV at a distance of 5 m (LOS) and 5.48 mV at a distance of 15 m (NLOS). The highest RF-DC conversion efficiency of our proposed rectenna reaches 77.6%. The rectenna potentially meets all requirements to power up the IoT applications.
Measuring environmental and landscape-related potential for tourism development in rural areas and assessment of its co-occurrence with tourist movement: The case of Poland
Authors: Mazur Marcin , Bednarek-Szczepańska Maria , Bański Jerzy , Mazurek Damian 
Published: July 2021

Abstract
The assessment of assets regarding their potential for tourism development is a well-recognised aspect of quantitative geographic research. This paper confines such matters to environmental and landscape-related attributes. The methodological objective is to propose a synthetic index for holistic measurement of a complex system of assets at the local level for Poland’s rural areas, followed by its empirical verification. The natural and landscape-related potential of a given area is perceived broadly, as the aspects involved are diverse and complementary: the quality of the landscape, the value of the environment, forest cover, relief, accessibility to surface waters and local bioclimate. The cognitive advantage of this research project is attained by confronting this index against a measure of tourist movement, as well as classifying rural areas by means of combining both dimensions. A considerable number of communes in Poland are characterised by relatively high potential, albeit they are not being exploited for tourism development to a correspondingly large degree.
Update of the Ventilation Network Related to Livezeni Mine
Authors: Biro Eva , Radu Sorin Mihai , Cioclea Doru , Gherghe Ion 
Published: July 2021

Abstract
The ventilation networks are associated with the set of underground mining works used for the extraction of useful mineral substances. Over time, the ventilation networks involve a change in the structure due to either the expansion or restriction of the mining works structure. For the establishment of air flows at the level of each active mining work, specialized programs are used at international level. These programs allow the modelling and solving of complex ventilation networks. The most advanced specialized programs are those from the VENTSIM range. The paper presents the updating of the ventilation network related to Livezeni mine, with the help of the VENTSIM program.
Energy Analysis of the Propulsion Shaft Fatigue Process in a Rotating Mechanical System Part III Dimensional Analysis
Authors: Korczewski Zbigniew , Marszałkowski Konrad 
Published: July 2021

Abstract
This article presents the third and last part of the problem of diagnosing the fatigue of marine propulsion shafts in terms of energy with the use of the action function, undertaken by the authors. Even the most perfect physical models of real objects, observed under laboratory conditions and developed based on the results of their research, cannot be useful in diagnostics without properly transferring the obtained results to the scale of the real object. This paper presents the method of using dimensional analyses and the Buckingham theorem (the so-called π theorem) to determine the dimensionless numbers of the dynamic similarity of the physical model of the propulsion shaft and its real ship counterpart, which enable the transfer of the results of the research on the energy processes accompanying the ship propulsion shaft fatigue from the physical model to the real object.
Evaluation of the Impact of International Trade Using Regression and Correlation Models
Authors: Čarný Štefan , Zitrický Vladislav 
Published: July 2021

Abstract
The connection of international economies in the world represents an important role for the development of modern economies of countries. This phenomenon is known as globalization. The article describes in more detail the dependence of the Slovak Republic on the economies of East Asia, where mathematical research was performed on macroeconomic indicators of imports and exports. The Slovak Republic is experiencing an increase in GDP for the entire reference period. The growth of economic indicators in the Slovak Republic is ensured mainly due to the strong integration of our economy into international logistics chains and the strongly developed automotive industry. However, assuming the COVID-19 crisis, several studies suggest a sharp decline in economic indicators, as international trade has had to be significantly reduced for some time. The countries we examined in the article have a significant impact on these areas, so our research was focused on the main sectors of the Slovak economy. The automotive industry, the metallurgical industry and the electronics industry were evaluated. Data from world statistics were evaluated using mathematical and statistical models. The result of the study was the confirmation of dependence in all the categories.
Gebe kadınların aile stresörleri ile başa çıkma yöntemleri ve karşılıklı mutluluk durumlarının değerlendirilmesi
Authors: İNEL MANAV Ayşe , GÖZÜYEŞİL Ebru , ÜNAL Esra 
Published: July 2021

Amaç: Bu çalışma, geniş ve çekirdek ailelerde yaşayan gebe kadınların aile stresörleri ile başa çıkma yöntemleri ve karşılıklı mutluluk durumlarını değerlendirmek amacıyla gerçekleştirilmiştir.
Gereç ve Yöntem: Tanımlayıcı tipte gerçekleştirilen çalışma 152’si çekirdek, 71’i geniş ailede yaşayan 223 gebe kadın ile gerçekleştirilmiştir. Araştırmanın verileri Kişisel Bilgi Formu, Aile Stresörleri ile Başa Çıkma Yöntemleri Ölçeği ve Karşılıklı Mutluluk Ölçeği ile toplanmıştır.
Bulgular: Çalışmaya katılan gebe kadınların yaş ortalamalarının 27.43±5.90 olduğu, %31.4’nün ortaokul mezunu olduğu, %70’nin gelir durumunun orta düzeyde olduğu ve gebeliklerin %83’nün planlı olduğu saptanmıştır. Geniş ve çekirdek ailede yaşayan kadınların Karşılıklı Mutluluk Ölçeği puan ortancaları arasında istatistiksel olarak anlamlı bir fark olmadığı tespit edilmiştir (p>0.05). Çekirdek ailelerde yaşayan gebe kadınların geniş ailelerde yaşayanlara göre Aile Stresörleri ile Başa Çıkma Yöntemleri Ölçeği alt boyutları incelendiğinde; Planlama, Eşler Arası İletişim, Aile İş Ayrımı, Bilişsel Yapılandırma, Birlik Beraberlik, Eşler Arası İlgi alt boyutları puan ortancaları arasında istatistiksel olarak anlamlı fark vardır (p