bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Two‐Wave Cross‐Lagged Study on AI Service Quality: The Moderating Effects of the Job Level and Job Role
Authors: Nguyen Tuyet‐Mai , Malik Ashish 
Published: July 2021

AbstractThis study examines whether the adoption of artificial intelligence (AI) in the workplace can make employees satisfied with AI service quality and increase their job satisfaction. The study's conceptual framework was tested using a cross‐lagged panel analysis (N = 313) of hotel employees and managers in Vietnam. This research shows that AI satisfaction with service quality mediated the impact of AI service quality on employees’ job satisfaction. Job level had a moderating effect on the impact of AI service quality on AI satisfaction and job satisfaction, such that AI service quality had an impact on AI satisfaction only in the non‐supervisory group but had an impact on job satisfaction in both non‐supervisory and supervisor/manager groups. AI service quality affected AI satisfaction in both job roles (frontline and back‐end employee roles), but only influenced job satisfaction for the back‐end employee role. The implications of our findings for future research and practice are discussed.
Development and first evaluation of an attractant impregnated adhesive tape against blood‐sucking flies
Authors: Zhu Junwei J. , Roh Gwang‐Hyun , Asamoto Yosuke , Bizati Kujtim , Liu Jen‐Chieh , Lehmann Alexander , Harrison Kyle , Taylor David B. , Otake Hironao 
Published: July 2021

AbstractStable flies are one of the most important arthropod pests of livestock that reduce cattle weight gain and milk production leading to annual economic losses in excess of $2 billion to the US cattle industry. The host‐seeking behavior is primarily mediated by associated odors from stable fly larval development environments and host animals. The present paper reports the development and evaluation of attractant‐impregnated adhesive tapes to reduce stable fly attacks on cattle. Laboratory bioassays showed that only m‐cresol impregnated adhesive tapes caught significantly more stable flies (16 ± 1) than the control tape without attractant added (7 ± 1), with a 77% fly recapture rate. Attractant‐impregnated adhesive tapes deployed in cattle feedlots showed significant impacts in reducing fly population, with a total of one million stable flies captured over a period of three weeks (mean catches from 57 596 to 102 088 stable flies per trap per week). It further relieved cattle stress with a significant reduction of biting fly avoidance behavior, (6 ± 0.4 cows observed with tail wagging in control vs. 3 ± 0.4 from the trap‐deployed). The efficacy of the developed tapes lasted up to 1‐week longevity, although 70% of m‐cresol was released starting from the second day. The m‐cresol impregnated adhesive tape provided an 80% reduction in cattle stress due to stable fly attack. This is the first report of a technology developed by integrating an attractant compound into an adhesive material on a plastic film with demonstrated effectiveness in trapping biting flies that attack livestock animals.
Anti‐inflammatory peptides and metabolomics‐driven biomarkers discovery from sea cucumber protein hydrolysates
Authors: Zhang Xuanming , Li Haonan , Wang Lizhen , Zhang Shanshan , Wang Fengxia , Lin Houwen , Gao Sheng , Li Xiaobin , Liu Kechun 
Published: July 2021

AbstractThe hydrolysates from Apostichopus japonicus sea cucumber are an important source of nitrogen that may be added to foods. We evaluated the effect of A. japonicus hydrolysates on inflammation‐associated leukocyte recruitment. The results revealed that leukocyte migration to the site of injury was significantly blocked by AJH‐1 (<10 kDa), suggesting a protective effect against CuSO4‐induced neuromast damage in a zebrafish model. Based on liquid chromatography/time‐of‐flight/mass spectrometry, and metabolomic analysis, the nine biomarker candidates in AJH‐1 were Val, Ala‐Pro‐Arg, Gly‐Lys, Asp propyl ester, Glu methyl ester, His butyl ester, Ile‐Ala‐Ala‐Lys, Tyr‐Lys, and Asn‐Pro‐Gly‐Lys. We used molecular docking to predict the binding affinity and docked position of the peptides onto the angiotensin converting enzyme (ACE). All the identified peptides had adequate binding affinity toward ACE, especially peptides Ala‐Pro‐Arg and Gly‐Lys. These peptides may be used in the development of therapeutic foods.Practical ApplicationThe study revealed the anti‐inflammatory properties of the fractionated sea cucumber protein hydrolysate (<10 kDa). The characteristic peptides may be used as functional ingredients in nutraceutical foods and beverages.
The health and educational costs of preterm birth to 18 years of age in Australia
Authors: Newnham John P. , Schilling Chris , Petrou Stavros , Morris Jonathan M , Wallace Euan M. , Brown Kiarna , Edwards Lindsay , Skubisz Monika M. , White Scott W. , Rynne Brendan , Arrese Catherine A. , Doherty Dorota A. 
Published: July 2021

BackgroundPreterm birth is the greatest cause of death up to five years of age and an important contributor to lifelong disability. There is increasing evidence that a meaningful proportion of early births may be prevented, but widespread introduction of effective preventive strategies will require financial support.AimsThis study estimated the economic cost to the Australian government of preterm birth, up to 18 years of age.Materials and MethodsA decision‐analytic model was developed to estimate the costs of preterm birth in Australia for a hypothetical cohort of 314 814 children, the number of live births in 2016. Costs to Australia’s eight jurisdictions included medical expenditures and additional costs to educational services.ResultsThe total cost of preterm birth to the Australian government associated with the annual cohort was estimated at $1.413 billion (95% CI 1047‒1781). Two‐thirds of the costs were borne by healthcare services during the newborn period and one‐quarter of the costs by educational services providing special assistance. For each child, the costs were highest for those born at the earliest survivable gestational age, but the larger numbers of children born at later gestational ages contributed heavily to the overall economic burden.ConclusionPreterm birth leaves many people with lifelong disabilities and generates a significant economic burden to society. The costs extend beyond those to the healthcare system and include additional educational needs. Assessments of economic costs should inform economic evaluations of interventions aimed at the prevention or treatment of preterm birth.
Radical plurality on universal grounds
Authors: Bobrowicz Ryszard , Gustafsson Lundberg Johanna 
Published: July 2021

AbstractThis paper focuses on recent debates between the proponents of individualism and communitarianism. As the authors argue, the dichotomous character of these debates is inherently problematic, as no one functions just as an individual or member. Starting from the discussion around the Netflix series "Unorthodox" in the Swedish context, the authors engage with Sharon Todd's radical conception of plurality, and K.E. Løgstrup's notions of interdependence and the resulting ethical demand to show how these debates could be reframed into the constructive tension between plurality and universality.
Mortality in pediatric hydrocephalus
Authors: Tully Hannah M , Doherty Dan , Wainwright Mark 
Published: July 2021

AimTo clarify the extent to which medical comorbidities and goals‐of‐care decisions influence death among individuals with childhood‐onset hydrocephalus.MethodThis was a retrospective cohort study of 1705 individuals (759 males, 946 females, mean age 11y 5mo, SD 6y 6mo, range 0–37y 7mo at last follow‐up) with childhood‐onset hydrocephalus, of whom 88 (5.2%) were deceased. Existing medical records, death records, and publicly available internet sources were analyzed. We estimated hazard ratios for putative risk factors through Cox regression based upon 10 529 person‐years of data and quantitatively and qualitatively analyzed the circumstances surrounding each death.ResultsMortality did not differ statistically by demographic factors, although higher proportions of non‐White and Hispanic individuals were deceased. Most deaths were related to medical comorbidities rather than hydrocephalus itself. Of the 14 deaths directly related to hydrocephalus, seven were caused by shunt complications and four occurred after decisions to forgo treatment, apparently in response to poor outcomes predicted by the medical team. Half the deaths were preceded by shifts to comfort‐based care; however, these decisions appeared to substantially change the patient’s clinical trajectory only half the time.InterpretationChildren are more likely to die with, rather than from, hydrocephalus. Our results emphasize the complexities of medical decision‐making and the influence of clinicians in guiding these choices.
Methodological considerations for studying neural oscillations
Authors: Donoghue Thomas , Schaworonkow Natalie , Voytek Bradley 
Published: July 2021

AbstractNeural oscillations are ubiquitous across recording methodologies and species, broadly associated with cognitive tasks, and amenable to computational modelling that investigates neural circuit generating mechanisms and neural population dynamics. Because of this, neural oscillations offer an exciting potential opportunity for linking theory, physiology and mechanisms of cognition. However, despite their prevalence, there are many concerns—new and old—about how our analysis assumptions are violated by known properties of field potential data. For investigations of neural oscillations to be properly interpreted, and ultimately developed into mechanistic theories, it is necessary to carefully consider the underlying assumptions of the methods we employ. Here, we discuss seven methodological considerations for analysing neural oscillations. The considerations are to (1) verify the presence of oscillations, as they may be absent; (2) validate oscillation band definitions, to address variable peak frequencies; (3) account for concurrent non‐oscillatory aperiodic activity, which might otherwise confound measures; measure and account for (4) temporal variability and (5) waveform shape of neural oscillations, which are often bursty and/or nonsinusoidal, potentially leading to spurious results; (6) separate spatially overlapping rhythms, which may interfere with each other; and (7) consider the required signal‐to‐noise ratio for obtaining reliable estimates. For each topic, we provide relevant examples, demonstrate potential errors of interpretation, and offer suggestions to address these issues. We primarily focus on univariate measures, such as power and phase estimates, though we discuss how these issues can propagate to multivariate measures. These considerations and recommendations offer a helpful guide for measuring and interpreting neural oscillations.
Decrease of ceramides with long‐chain fatty acids in psoriasis: Possible inhibitory effect of interferon gamma on chain elongation
Authors: Kim Bo‐Kyung , Shon Jong Cheol , Seo Hee Seok , Liu Kwang‐Hyeon , Lee Jong Won , Ahn Sung Ku , Hong Seung Phil 
Published: July 2021

AbstractReportedly, decreases in fatty acid (FA) chain length of ceramide (CER) are associated with interferon‐γ (IFN‐γ), which shows increased expression in psoriasis. However, the underlying mechanism of this association remains unclear. Therefore, in this study, we aimed to clarify this association between FA chain length of CER, IFN‐γ, and the major transcriptional factors involving psoriasis. CER profiling according to FA chain length and class was performed in murine epidermis (n = 10 BALB/c mice topically treated with imiquimod, n = 10 controls) and human stratum corneum (SC) (n = 12 psoriasis, n = 11 controls). The expression of lipid synthetic enzymes, including elongases (ELOVLs), in murine epidermis was also measured using RT‐PCR. Furthermore, the association of IFN‐γ with various enzymes and transcription factors involved in the generation of long‐chain CERs was also investigated using in vitro keratinocyte. A significant decrease in the percentage of long‐chain CERs was observed in psoriasis‐like murine epidermis and human psoriatic SC. Additionally, the expression levels of ELOVL1, ELOVL4, and ceramide synthase3 (CerS3) were significantly decreased in psoriasis‐like murine epidermis and IFN‐γ‐treated keratinocyte. There was also a significant decrease in the expression of transcriptional factors, including peroxisome proliferator‐activated receptor (PPAR), in IFN‐γ treated keratinocyte. Thus, it could be suggested that IFN‐γ may regulate ELOVL and CerS levels by down‐regulating the transcriptional factors. Additionally, given the possible involvement of PPARs or liver X receptor agonist in the CER elongation process, they may serve as potential therapeutic agents for lengthening the CER FAs in psoriasis.
Association between bacteria other than Helicobacter pylori and the risk of gastric cancer
Authors: Gunathilake Madhawa , Lee Jeonghee , Choi Il Ju , Kim Young‐Il , Kim Jeongseon 
Published: July 2021

AbstractBackgroundThe gastric microbiota, including Helicobacter pylori (HP), has a remarkable role in gastric cancer (GC) occurrence. Evidence for the role of non‐HP bacteria in GC risk is limited. We aimed to observe the association between bacteria other than HP and risk of GC in a Korean population.MethodsIn this study, 268 GC cases and 288 healthy controls were included. Demographic data and total energy intake data were collected using a general questionnaire and a semiquantitative food frequency questionnaire, respectively. 16S rRNA gene sequencing was performed using DNA extracted from gastric biopsy samples.ResultsActinobacteria, Bacteroidetes, Firmicutes, Fusobacteria, and non‐HP Proteobacteria were the five main phyla in the gastric environment. The five phyla were negatively related to the relative abundance of Helicobacter species (all p < 0.001). The Shannon index, richness, and Pilou‐evenness were negatively correlated with Helicobacter species (all p < 0.001), while the microbial dysbiosis index was positively correlated with Helicobacter species (p < 0.001). Participants with a higher relative abundance of Actinobacteria species showed a significantly increased risk of GC (OR: 3.16, 95% CI = 1.92–5.19, p‐trend<0.001). The non‐HP microbiota composition among the four groups (HP+cases, HP‐ cases, HP+controls, and HP‐ controls) was significantly different (ANOSIM R = 0.10, p = 0.001).ConclusionOther than HP, several bacterial species might be associated with GC risk. HP status and GC status could determine the differences in microbial compositions. Further large prospective studies are warranted to confirm our findings.
Identifying sectoral impacts on global scarce water uses from multiple perspectives
Authors: Yang Xuechun , Liang Sai , Qi Jianchuan , Feng Cuiyang , Qu Shen , Xu Ming 
Published: July 2021

AbstractScarce water uses driven by hotspots in production and consumption stages of global supply chains have been well studied. However, hotspots in primary inputs and intermediate transmission stages also leading to large amounts of global scarce water uses are overlooked. This gap can lead to the underestimation of the impacts of certain nation sectors on global scarce water uses. This study identifies critical primary suppliers and transmission centers in global supply chains contributing to scarce water uses, based on environmentally extended multi‐regional input‐output (EE‐MRIO) model and complex network analysis methods. Results show that some critical primary suppliers (e.g., the service auxiliary to financial intermediation sector in the United States and the financial intermediation services sector in India) and transmission centers (e.g., the raw milk sector in the United States and the transmission services of electricity sector in China) are unidentifiable in previous studies. These findings provide hotspots for supply‐side measures (e.g., optimization of primary input and product allocation behaviors) and productivity improvement measures. The critical inter‐sectoral transactions (mainly involving the agricultural and food products sectors in India, China, and the United States) further provide explicit directions for these measures. Moreover, this study conducts a community detection, which identifies communities (i.e., the clusters of nation sectors closely interconnected) leading to global scarce water uses. Most of the communities involve sectors from different nations, providing foundations for international cooperation strategies.
Ankle structure of the Tokay gecko (Gekko gecko) and its role in the deployment of the subdigital adhesive system
Authors: Higham Timothy E. , Zhuang Minga , Russell Anthony P. 
Published: July 2021

AbstractThe remarkable ability of geckos to adhere to smooth surfaces is often thought of in terms of external structures, including the branching setae that make contact with the surface producing van der Waals forces. Some geckos also exhibit unique movements of the distal segments of the limbs during locomotion and static clinging, including active digital hyperextension and considerable pedal rotation. During static clinging, geckos can exhibit considerable adduction/abduction of the pes while the crus and thigh remain firmly adpressed to the substratum. This decoupling of pedal adduction/abduction from ankle flexion/extension and pedal long‐axis rotation is a significant departure from pedal displacements of a typical lizard lacking adhesive ability. The structure of the ankle is likely key to this decoupling, although no detailed comparison of this complex joint between pad‐bearing geckos and other lizards is available. Here we compare the configuration of the mesotarsal joint of nongekkotan lizards (Iguana and Pristidactylus) with that of the Tokay gecko (Gekko gecko) using prepared skeletons, scanning electron microscopy, and micro‐computed tomographic (µCT) scans. We focus on the structure of the astragalocalcaneum and the fourth distal tarsal. The mesotarsal joint exhibits a suite of modifications that are likely associated with the secondarily symmetrical pes of pad‐bearing geckos. For example, the lateral process of the astragalocalcaneum is much more extensive in G. gecko compared with other lizards. The mesotarsal joint exhibits several other differences permitting dissociation of long‐axis rotation of the pes from flexion–extension movement, including a reduced ventral peg on the fourth distal tarsal, an articulatory pattern dominated by a well‐defined, expansive distomesial notch of the astragalocalcaneum, and an associated broad proximodorsal articulatory facet of the fourth distal tarsal. Pad‐bearing geckos are capable of effectively deploying their intricate adhesive system across a broad array of body angles because of this highly modified ankle. Future research should determine whether the differences encountered in G. gecko (and their extent) apply to the Gekkota as a whole and should examine how the elements of the ankle move dynamically during locomotion across a range of taxa.
Epidemiological trends of HBV and HDV coinfection among Viennese HIV+ patients
Authors: Schmidbauer Caroline , Chromy David , Schmidbauer Victor U. , Schwarz Michael , Jachs Mathias , Bauer David J. M. , Binter Teresa , Apata Michael , Nguyen Dung T. , Mandorfer Mattias , Simbrunner Benedikt , Rieger Armin , Mayer Florian , Breuer Monika , Strassl Robert , Schmidt Ralf , Holzmann Heidemarie , Trauner Michael , Gschwantler Michael , Reiberger Thomas 
Published: July 2021

AbstractBackground and AimsDespite vaccination recommendations, hepatitis B (HBV) and D (HDV) coinfections are common in HIV+individuals.MethodsHBV immunization status (anti‐HBs) as well as HBV (HBsAg/HBV‐DNA) and HDV (anti‐HDV) coinfection rates were assessed in 1870 HIV+individuals at HIV diagnosis (baseline, BL) and last follow‐up (FU).ResultsSixty‐eight (3.6%) HIV patients were never tested for HBV. At BL, 89/1802 (4.9%) HIV patients were HBV coinfected. Four hundred and fifteen (23.0%) showed virological HBV clearance [HBsAg(‐)/anti‐HBc(+)/anti‐HBs(+)] and 210 (11.7%) presented with anti‐HBc(+) only. Seven hundred and ten (39.4%) were HBV naïve [HBsAg(‐)/anti‐HBs(‐)/anti‐HBc(‐)/HBV‐DNA(‐)], but only 378 (21.0%) received vaccinations with detectable anti‐HBs(+) titres. Among the 89 HBV/HIV‐coinfected patients, only 52 (58.4%) were tested for HDV: 11/49 (22.4%) had anti‐HDV(+) and 3/12 (25.0%) showed HDV‐RNA viraemia. During a median FU of 6.5 (IQR 7.2) years, 44 (4.6%) of the 953 retested BL HBV‐negative patients acquired new HBV infection (including 15/304, 4.9% of vaccinated patients). Of the 89 patients, 22 (24.7%) patients cleared their HBsAg, resulting in 60/1625 (3.7%) HIV/HBV individuals at FU: 34 (56.7%) showed HBV‐DNA suppression and 15 (25.0%) were HBV viraemic, while 12/89 (13.5%) remained without a FU test. Vaccinations induced anti‐HBs(+) in 137 of the retested 649 (21.1%) BL HBV‐naïve patients.ConclusionHBV testing is well established among Viennese HIV+patients with HBV coinfection rates around 4%‐5%. HBV vaccinations are insufficiently implemented since anti‐HBs titres were detected in only 21.1% of HBV‐naive HIV(+) patients and new HBV infections occurred in previously vaccinated patients. HDV testing is not systematically performed despite up to 25% of HIV/HBV patients may show HDV coinfection.
The effect of exercise on the protein profile of rat knee joint intra‐ and extra‐articular ligaments
Authors: Kharaz Yalda A. , Birch Helen , Chester Alexandra , Alchorne Eleanor , Simpson Deborah , Clegg Peter , Comerford Eithne 
Published: July 2021

Injuries to the intra‐articular anterior cruciate ligament (ACL) and the extra‐articular medial collateral ligament (MCL) result in significant knee joint instability, pain, and immobility. Moderate endurance‐type exercise can increase ligament strength but little is known on the effect of short‐term regular bouts of high‐intensity exercise on the extracellular matrix (ECM) structure of knee ligaments. Therefore, this study aimed to identify the effect of short‐term regular bouts high exercise on the proteome of the rat ACL and MCL using mass spectrometry. Sprague‐Dawley male rats (n = 6) were split into control and exercise groups, and subjected to high‐intensity training for four 4 weeks followed by proteomic analyses of the ACL and MCL. Knee joint health status was assessed using OARSI and a validated histological scoring system. Histopathological analyses demonstrated no significant changes in either in cruciate, collateral ligaments, or cartilage between the control and exercised knee joints. However, significant proteins were found to be more abundant in the exercised ACL compared to ACL control group but not between the exercised MCL and control MCL groups. The significant abundant proteins in ACL exercise groups were mostly cytoskeletal, ribosomal and enzymes with several abundant matrisomal proteins such as collagen proteins and proteoglycans being found in this group. In conclusion, our results indicate that short‐term regular bouts of high‐intensity exercise have an impact on the intra‐articular ACL but not extra‐articular MCL ECM protein expression.