bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Relation between Fatigue Level and Nurses’ Caring Behavior in The Orthopedic Department
Authors: AbdElazeem Yasmin F. M. , Ahmed Rasha F. , Aly Eman F. A. M. 
Published: April 2021

Contents: Caring is a concept that is inherently difficult to define. The term caring is expressed in different ways in many cultures. Nurse's caring can impact a person's life processes, wellbeing, and functioning. On the other hand, fatigue is a subjective unpleasant feeling ranging from tiredness to exhaustion that could be physical, mental, or both. It may significantly interfere with functioning and may persist despite periods of rest.
Aim: The present study investigates the relation between fatigue level and nurses' caring behavior in the orthopedic department.
Methods: Research formulates three questions. What is the nurses' level of fatigue in the orthopedic department? What are the nurses' caring behaviors in the orthopedic department? What is the relation between fatigue level and nurses' caring behavior in the orthopedic department? The study utilized a correlational research design. The study conducted in El Hadra Orthopedic and Traumatology University Hospital, Alexandria, Egypt, on all available nurses (50 nurses) who provide direct patient care and work in the previously mentioned setting. Two tools were used for data collection. Structured interview questionnaire; It consists of two parts. The first part was concerned with socio-demographic data, past medical history of psychological problems, and chronic illness. The second part was Fatigue Visual Analog Scale (VAS), a one-dimensional scale, consisting of an unmarked 10 cm line to rate the nurses' level of fatigue. The second tool was the Orthopedic Nurse Caring Behavior Observation Checklist. This tool was used to assess nurses' caring behavior toward orthopedic patients through concealed observation.
Results: It was observed that 60.0% of studied nurses had a severe level of fatigue. The study showed a moderate level of caring behaviors with a mean of 199.92±13.50 for the morning shift nurses and 222.34±14.27 for the nurses in the evening shift. The study evidenced a significant correlation between fatigue level and overall caring behavior.
Conclusion: About two-thirds of the studied nurses had a severe level of fatigue. The overall nurses' caring behaviors dimensions were of a moderate degree. There is a significant positive correlation between fatigue level and the overall nurses' caring behaviors in both morning and evening shifts in the orthopedic department. The study recommended to provide nurses with fatigue countermeasure strategies and to provide the organization with strategies to overcome fatigue. Nurses are recommended to pay more attention to caring behaviors.
Nurturing Cultural Diversity in Higher Education: A Critical Review of Selected Models
Authors: Guo Shibao , Jamal Zenobia 
Published: April 2021

Canadian universities and colleges are becoming increasingly ethnoculturally diverse. Two major social forces have contributed to this change: immigration and increasing enrolment of international students. Minority and international students bring their values, language, culture and educational background to our campuses, to add to and enrich our educational environments. To build an inclusive education, we have the ethical and educational responsibility to embrace such difference and diversity and to integrate it into all aspects of university life, including teaching and learning. However, in our daily encounter with cultural diversity we still confront many challenges, such as the colourblind and the “difference as deficit” perspectives, partially resulting from a lack of knowledge and readiness to approach diversity. The goal of this article is to bridge this gap by examining three selected models commonly used to nurture cultural diversity in higher education: the intercultural education model, the multicultural education model, and the anti-racist education model. It is hoped that this discussion will benefi t the university community in Canada as well as in other countries where diversity prevails.
Du fait de l’immigration et de l’augmentation du nombre d’étudiantes et d’étudiants internationaux, les universités et collèges du Canada sont de plus en plus diversifi és sur le plan ethnoculturel. Les étudiantes et étudiants issus des minorités ethniques ainsi que d’autres pays apportent avec eux leurs valeurs, langues et cultures, ce qui enrichit d’autant le milieu éducatif. Il est de notre responsabilité à la fois morale et éducative, si nous voulons créer un environnement inclusif, d’intégrer ces différences et cette diversité dans tous les aspects de la vie universitaire, y compris l’enseignement et l’apprentissage. Toutefois, dans nos rencontres quotidiennes avec la diversité culturelle, nous sommes confrontés à plusieurs défi s, notamment les modèles dits « aveugles à la couleur » et la perception de « la différence comme défi cit ». Ces perspectives résultent en partie d’un manque de connaissances et d’attitudes peu disposées à accueillir la diversité culturelle. Le but de cet article est de répondre à ces défi s en examinant trois modèles fréquemment employés pour encourager la diversité culturelle dans l’enseignement supérieur : l’éducation interculturelle, l’éducation multiculturelle et l’éducation anti-raciste. Nous espérons que cette discussion aura des effets positifs pour la communauté universitaire du Canada et d’autres pays marqués par la diversité.
Vaksinasi COVID-19 bagi Pekerja, Harapan Pulihnya Produktivitas
Authors: Muchtaruddin Mansyur  
Published: April 2021

Pandemi COVID-19 dan Produktifitas
Pandemi COVID-19 telah berdampak merugikan masyarakat, tidak hanya kesakitan dan kematian tetapi juga pada berbagai bidang sosial dan ekonomi. Efek pandemi dengan berbagai situasi yang berhubungan seperti pembatasan kegiatan, pembatasan perdagangan, pembatasan pergerakan, dan penguncian daerah menyebabkan terbatasnya kegiatan berbagai sektor produksi. Pada bulletin Word Food Program COVID-19: Economic and Food Security Implications (4th Edition)1 merilis data tentang situasi Indonesia setelah 9 bulan mengalami masa pandemi. Dari data yang disampaikan didapatkan bahwa Product Domestic Bruto (PDB) Indonesia terus menyusut selama kuartal kedua berturut-turut karena pandemi, dengan tingkat inflasi tahunan meningkat menjadi 1,6% pada November 2020. Harapan optimis dengan gambaran secara berangsur adanya pertumbuhan positif di semua sektor ekonomi.
Valores relativos ao trabalho e perspectiva de futuro para a geração Z
Authors: Pauli Jandir , Guadagnin Alana , Ruffatto Juliane 
Published: April 2021

A Geração Z está ingressando no mercado de trabalho e compreender seus valores é importante para dimensionar o espaço do trabalho em suas vidas, bem como as expectativas organizacionais e sociais a ele associadas. Esta questão é relevante para as organizações desenvolverem políticas de atração e engajamento específicas, dado quea literatura aponta que os valores relativos ao trabalho da geração Z são distintos das gerações anteriores. Esse artigo visa a descrever a influência dos valores relativos ao trabalho na expectativa de futuro para integrantes da geração Z. Foi realizado uma pesquisa quantitativa descritiva, de tipo Survey, com 224 jovens em idade escolar e que ainda não estão no mercado de trabalho. Entre os resultados, evidencia-se a influência dos valores ligados a estabilidade, diversidade no trabalho e relações sociais autênticas na expectativa de futuro destes jovens. Observou-se também que o prestígio exerce influência negativa na expectativa de futuro, indicando a busca por relações horizontais e orientadas para a transformação social.
Comparison of the Efficacy of Vindesine and Leurocristine for Pediatric Acute Lymphoblastic Leukemia and their Effects on Quality of Life
Authors: Shi Xiaowei , Zhang Pisheng , Du Xiaohong , Chen Lieguang , Li Shuangyue , Fan Zheng 
Published: April 2021

IntroductionThe present study aimed to compare the efficacy of vindesine with that of leurocristine for pediatric acute lymphoblastic leukemia and their effects on the quality of life.Material and methodsWe included 94 patients with pediatric acute lymphoblastic leukemia admitted to our hospital for treatment and categorized them into two groups: treatment with vindesine (group A, n = 48) and treatment with leurocristine (group B; n = 48). The effective rate, adverse reactions (thrombocytopenia, anemia, peripheral neurotoxic reaction, infection, nausea, and vomiting) and basic clinical conditions (medical expenses and length of hospital stay) of the patients were observed. In addition, IL-6 and TNF-α expressions were determined by ELISA before and after treatment, posttreatment quality of life score was determined by the Karnofsky performance scale (KPS), and the 5-year overall survival was determined in both groups.ResultsGroup A showed no statistical difference in the total efficacy rate and 5-year overall survival after treatment (P > 0.05) and had lower medical expenses, length of hospital stay, IL-6 and TNF-α expressions, and total incidence of adverse reactions and higher KPS scores than group B (P < 0.05).ConclusionsAlthough no statistical difference was observed between vindesine and leurocristine in treating pediatric acute lymphoblastic leukemia, patients administered vindesine had fewer adverse reactions, shorter length of hospital stay, lower medical expenses, and higher quality of life than those administered leurocristine, indicating a potential association with decreased serum IL-6 and TNF-α expressions.
miR-210 regulates vascular endothelial cell apoptosis in arteriosclerosis obliterans through the JAK1-STAT3 pathway
Authors: Hu Songjie , Xu Zhongjian , Lang Dehai 
Published: April 2021

IntroductionAtherosclerosis is a continuously worsening chronic condition that starts in the arteries and may then affect other blood vessels. There is increasing evidence linking microRNAs to the development of arteriosclerosis obliterans (ASO). Quantitative reverse transcription polymerase chain reaction (qRT-PCR) was applied in this study to detect miR-210-5p (miR-210) expression, and significant upregulation was observed in human arterial walls where ASO was prevalent.Material and methodsThe proliferation of human umbilical vascular endothelial cells (HUVECs) with various levels of miR-210 expression was assessed via MTT and colony-formation assays. Cell proliferation was significantly promoted in HUVECs with upregulated miR-210 levels and reduced in HUVECs with downregulated miR-210 levels.ResultsFlow cytometric analysis of cells stained with annexin V-FITC and propidium iodide data demonstrated that miR-210 inhibited apoptosis, while miR-210 inhibition promoted apoptosis by mediating pro-apoptotic protein expression levels. These results were verified using a dual-luciferase reporter gene assay system, which showed that Janus kinase 1 (JAK1) was directly targeted by miR-210, while an miR-210 mimic significantly decreased downstream JAK1 and signal transducer and activator of transcription 3 (STAT3) activation at a post-transcriptional level in HUVECs, as detected by western blotting and qRT-PCR. Further inhibition of either JAK1 or STAT3 counteracted the effect of miR-210 on HUVEC proliferation and apoptosis. These findings suggest that miR-210 promotes HUVEC proliferation, at least in part, by targeting the JAK1-STAT3 signaling axis.ConclusionsThis study provides insights into the contribution of the miR-210-JAK1-STAT3 axis and its underlying mechanisms to ASO pathology.
Changes in the quality of life of patients with Blount’s disease undergoing simultaneous bilateral varus deformity correction with the use of the Ilizarov method.
Authors: Szelerski Łukasz , Żarek Sławomir , Górski Radosław , Mochocki Karol , Górski Ryszard , Kozłowska Andżelika , Małdyk Paweł , Morasiewicz Piotr 
Published: April 2021

IntroductionBlount’s disease is a growth disorder of the proximal tibia, which leads to the varus deformity and internal rotation of this bone. The treatment is mainly surgical and involves proximal tibial osteotomy and deformity correction. The aim of this study was to assess the change in the quality of life of patients with tibia vara deformity who underwent correction via the Ilizarov method.Material and methodsA total of 23 Blount’s disease patients who had undergone bilateral varus deformity correction with the Ilizarov method were included in this study. The following parameters were assessed retrospectively: duration of treatment with Ilizarov frames, baseline and postoperative values of the medial proximal tibial angle (MPTA) and mechanical axis deviation (MAD). The quality of life was assessed with a Short Form (SF)-36 survey.ResultsThe study population comprised 13 females and 10 males (mean age of 28.43), in whom the Ilizarov fixators were kept for an average duration of 106.65 days. MAD values diminished significantly after the surgery. We also observed significant increases in the MPTA values. The SF-36 scores increased across all of the questionnaire’s domains, which indicates a significant improvement in the postoperative quality of life.ConclusionsSimultaneous bilateral correction of the varus deformity with Ilizarov external fixators is a safe and effective treatment method. It helps reduce pain and improve gait, which translates to improving the quality of life in all its aspects. The duration of treatment depends to a large extent on the degree of patient cooperation, their attitude, and self-discipline.
Wayne Readings 2021. Expert Council «Nutritional Deficiency – a Global Medical Problem. Do we all know about its consequences?»
Authors: Гируцкая Е.О. 
Published: April 2021

Рассмотрена проблема нутритивной недостаточности у пациентов с неврологическими заболеваниями, обсуждавшаяся на Совете экспертов в рамках Вейновских чтений 2021 г. Нехватка необходимых веществ в рационе больных неврологического, онкологического, эндокринологического и других профилей способствует развитию осложнений, и в первую очередь инфекционных: пневмоний, пролежней и др. Показано, что нутритивная поддержка – эффективный метод восстановления в комплексной терапии заболеваний у пациентов всех возрастов. Приводятся современные международные рекомендации по введению нутритивной поддержки и результаты исследований по оценке применения сипингового питания.
The problem of nutritional deficiency in patients with neurological diseases, discussed at the Council of Experts within the framework of Wayne Readings in 2021, is considered. The lack of necessary substances in the diet of patients with neurological, oncological, endocrinological and other profiles contributes to the development of complications, and primarily infectious: pneumonia, bedsores, etc. It has been shown that nutritional support is an effective method of recovery in the complex therapy of diseases in patients of all ages. The article provides modern international recommendations for the introduction of nutritional support and the results of studies to assess the use of sipping nutrition.
Clinical and epidemiological features of acute intestinal infections caused by opportunistic enterobacteria in young children
Authors: Харченко Г.А. , Кимирилова О.Г. 
Published: April 2021

Установлены клинико-эпидемиологические особенности острых кишечных инфекций (ОКИ), вызванных условно-патогенными энтеробактериями (УПЭ) у детей раннего возраста, в зависимости от этиологического фактора. Источниками информации являлись данные Управления Роспотребнадзора по Астраханской области (АО), медицинская документация (720 историй болезни) пациентов в возрасте до 1 года, лечившихся в ГБУЗ ОИКБ им. А. М. Ничоги, Астрахань, с января 2019 по декабрь 2020 г. включительно. ОКИ, вызванные УПЭ у детей в АО, составляют 74%, в том числе у детей в возрасте до 1 года – 60% от общего количества больных ОКИ уточненной бактериальной этиологии. Независимо от этиологического фактора ОКИ, вызванные УПЭ, протекали в виде моноинфекции (83%) средней степени тяжести (62%). Симптомы интоксикации имели прямую корреляционную связь (r = от 0,52 до 0,76; p < 0,001) с выраженностью диарейного синдрома и дегидратации. С уменьшением возраста ребенка увеличивалась продолжительность купирования этих симптомов (r = -0,72; p < 0,001).
Clinical and epidemiological features of acute intestinal infections (AKI) caused by opportunistic enterobacteria (UPE) in young children, depending on the etiological factor were established. The information sources were the data of Rospotrebnadzor Administration in the Astrakhan oblast (AO), medical documentation (720 case histories) of patients under the age of 1 year treated in GBUZ «Regional clinical infectious hospital named. A. M. Nichogi» Astrakhan from January 2000 through December 2020. AKI caused by UPE in children in AO is 74%, including 60% in children under 1 year of age, of the total number of patients with AKI of specified bacterial etiology. Regardless of the etiological factor, AKI caused by UPE occurred in the form of monoinfection (83%), moderate severity (62%). Symptoms of intoxication had a direct correlation (r = 0,52 to 0,76; p < 0.001) with the severity of diarrheal syndrome and dehydration. With a decrease in the age of the child, the duration of relief of these symptoms increased (r = -0,72; p < 0,001).
Evaluating seismic beamforming capabilities of distributed acoustic sensing arrays
Authors: van den Ende Martijn P. A. , Ampuero Jean-Paul 
Published: April 2021

Abstract. The versatility and cost efficiency of fibre-optic distributed acoustic sensing (DAS) technologies facilitate geophysical monitoring in environments that were previously inaccessible for instrumentation. Moreover, the spatio-temporal data density permitted by DAS naturally appeals to seismic array processing techniques, such as beamforming for source location. However, the measurement principle of DAS is inherently different from that of conventional seismometers, providing measurements of ground strain rather than ground motion, and so the suitability of traditional seismological methods requires in-depth evaluation. In this study, we evaluate the performance of a DAS array in the task of seismic beamforming, in comparison with a co-located nodal seismometer array. We find that, even though the nodal array achieves excellent performance in localising a regional ML 4.3 earthquake, the DAS array exhibits poor waveform coherence and consequently produces inadequate beamforming results that are dominated by the signatures of shallow scattered waves. We demonstrate that this behaviour is likely inherent to the DAS measurement principle, and so new strategies need to be adopted to tailor array processing techniques to this emerging measurement technology. One strategy demonstrated here is to convert the DAS strain rates to particle velocities by spatial integration using the nodal seismometer recordings as a reference, which dramatically improves waveform coherence and beamforming performance and warrants new types of “hybrid” array design that combine dense DAS arrays with sparse seismometer arrays.
Results of chemoembolization in hepatocellular cancer
and metastatic liver damage
Authors: Shakeyev K. , Kabildina N. , Lytkin V. , Zhumakaev A. , Kruk E. , Usembekov U. , Murat A. 
Published: April 2021

Relevance: Treatment of patients with hepatocellular
cancer remains a complex problem in modern oncology.
Purpose: To evaluate the effectiveness of chemoembolization in hepatocellular cancer and metastatic liver disease.
Results: During and after the procedure, the risk
of complications was minimal: in 2 cases (0.25%), liver
necrosis and death from cardiovascular insufficiency
were recorded after five therapy courses. Eleven patients (23.9%) with a continued tumor growth showed a negative response and were administered symptomatic treatment.
Conclusion: In primary hepatocellular cancer and
metastatic liver lesions, chemoembolization is one of the
priorities in interventional radiology and a stage of complex treatment. This method is low-traumatic due to a minimal toxic effect of the chemotherapy drug. This method is indicated for inoperable liver tumors because a high concentration of an anticancer drug is delivered right to the focus and ensures a prolonged tumor exposure, with minimal risk of complications during and after the procedure. In our observations, complications in the form of necrosis and death occurred in 2 (0.25%) cases
Radiation injuries during combined radiation treatment of locally distributed cervical cancer: A literary review
Authors: Adylkhavov T. , Zhumakanova N. , Kamzina G. , Musulmanova M. , Andreyeva O. , Lipikhina А. , Sabekov Y. , Bekkali G. , Musina A. 
Published: April 2021

Relevance: Radiation therapy is one of the leading methods of treating malignant tumors of female genital organs. However, modern radiotherapeutic equipment technical capacity does not exclude the possibility of radiation complications from
healthy organs and tissues in the radiation zone. During radiation treatment (administered independently or in combination
with other methods), patients develop local radiation reactions of different intensity from related organs, such as the bladder,
rectum, and vagina, which significantly deteriorate patients’ quality of life. This also leads to involuntary interruptions in treatment and, finally, worsens the treatment outcome.
Purpose: To describe radiation injuries to pelvic organs in cervical cancer radiation treatment. It analyzes the frequency
and evidence of early and late radiation reactions from the affected organs.
Results: Radiation injuries to the pelvic organs form the basis of radiation pathology in patients with cervical cancer and
largely determine cured patients’ quality of life. Radiation complications of grade II-III, less often IV, are frequent after radiation
treatment for pelvic cancer, especially cervical cancer.
Conclusions: Despite the improvements in radiation treatment methods, there is still no unified system for preventing radiation reactions that would include algorithms for diagnosing and treating early and late radiation reactions using modern
medications and non-pharmacological options. The development and implementation of an algorithm for the correction of
radiation reactions after radiation and complex treatment for cervical cancer would timely prevent radiation and combined
complications from target organs and improve patients’ quality of life.
The Responsibility to Be Hard: Comments on Ken Gemes's “The Biology of Evil”
Authors: Feldblyum Leonard 
Published: April 2021

Abstract
In this article, I show that attending to Nietzsche's views about breeding and human enhancement reveals two important ways in which Ken Gemes's account of Nietzsche's uses of the rhetoric of degeneration and Verjüdung must be modified. First, attending to Nietzsche's views about breeding reveals that methods like isolation, quarantine, excision, and extermination are not merely for the weak, as Gemes claims. In fact, for Nietzsche such methods are crucial for producing and maintaining healthy, strong people and societies. More generally, such methods play a vital role in Nietzsche's philosophy, including with respect to his conception of health. Second, contrary to Gemes's claim that Nietzsche was not interested in the actual Jews of his time, I show that Nietzsche was very interested in them, and thought they were important precisely for their relevance to his interest in breeding a new European aristocracy.