bluuebunny/crossref_metadata_2025_split huggingface dataset:
A bifluorescent-based assay for the identification of neutralizing antibodies against SARS-CoV-2 variants of concern in vitro and in vivo
Authors: Chiem Kevin , Vasquez Desarey Morales , Silvas Jesus A. , Park Jun-Gyu , Piepenbrink Michael S. , Sourimant Julien , Lin Michelle J. , Greninger Alexander L. , Plemper Richard K. , Torrelles Jordi B. , Walter Mark R. , de la Torre Juan C. , Kobie James K. , Ye Chengjin , Martinez-Sobrido Luis 
Published: June 2021

ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged at the end of 2019 and has been responsible for the still ongoing coronavirus disease 2019 (COVID-19) pandemic. Prophylactic vaccines have been authorized by the United States (US) Food and Drug Administration (FDA) for the prevention of COVID-19. Identification of SARS-CoV-2 neutralizing antibodies (NAbs) is important to assess vaccine protection efficacy, including their ability to protect against emerging SARS- CoV-2 variants of concern (VoC). Here we report the generation and use of a recombinant (r)SARS-CoV-2 USA/WA1/2020 (WA-1) strain expressing Venus and a rSARS-CoV-2 expressing mCherry and containing mutations K417N, E484K, and N501Y found in the receptor binding domain (RBD) of the spike (S) glycoprotein of the South African (SA) B.1.351 (beta, β) VoC, in bifluorescent-based assays to rapidly and accurately identify human monoclonal antibodies (hMAbs) able to neutralize both viral infections in vitro and in vivo. Importantly, our bifluorescent-based system accurately recapitulated findings observed using individual viruses. Moreover, fluorescent- expressing rSARS-CoV-2 and the parental wild-type (WT) rSARS-CoV-2 WA-1 had similar viral fitness in vitro, as well as similar virulence and pathogenicity in vivo in the K18 human angiotensin converting enzyme 2 (hACE2) transgenic mouse model of SARS-CoV-2 infection. We demonstrate that these new fluorescent-expressing rSARS- CoV-2 can be used in vitro and in vivo to easily identify hMAbs that simultaneously neutralize different SARS-CoV-2 strains, including VoC, for the rapid assessment of vaccine efficacy or the identification of prophylactic and/or therapeutic broadly NAbs for the treatment of SARS-CoV-2 infection.
OJIP chlorophyll fluorescence induction profiles and plastoquinone binding affinity of the Photosystem II assembly intermediate PSII-I from Thermosynechococcus elongatus
Authors: Zabret Jure , Nowaczyk Marc M. 
Published: June 2021

AbstractBinding of Psb28 to the photosystem II assembly intermediate PSII-I induces conformational changes to the PSII acceptor side that impact charge recombination and reduce the in situ production of singlet oxygen (Zabret et al. 2021, Nat. Plants 7, 524-538). A detailed fluorometric analysis of the PSII-I assembly intermediate compared with OEC-disrupted and Mn-depleted PSII complexes showed differences between their variable (OJIP) chlorophyll fluorescence induction profiles. These revealed a distinct destabilisation of the QA- state in the PSII-I assembly intermediate and inactivated PSII samples related to an increased rate of direct and safe charge recombination. Furthermore, inactivation or removal of the OEC increases the binding affinity for plastoquinone analogues like DCBQ to the different PSII complexes. These results might indicate a mechanism that further contributes to the protection of PSII during biogenesis or repair.
Multiobjective optimization of the LASER aircraft wing’s composite structural design
Authors: Ricci Juan Tamassia , Coimbra Rogerio Frauendorf Faria , Gomes Guilherme Ferreira 
Published: June 2021

Purpose
Aircraft wings, one of the most important parts of an aircraft, have seen changes in its topological and design arrangement of both the internal structures and external shape during the past decades. This study, a numerical, aims to minimize the weight of multilaminate composite aerospace structures using multiobjective optimization.

Design/methodology/approach
The methodology started with the determination of the requirements, both imposed by the certifying authority and those inherent to the light, aerobatic, simple, economic and robust (LASER) project. After defining the requirements, the loads that the aircraft would be subjected to during its operation were defined from the flight envelope considering finite element analysis. The design vector consists of material choice for each laminate of the structure (20 in total), ply number and lay-up sequence (respecting the manufacturing rules) and main spar position to obtain a lightweight and cheap structure, respecting the restrictions of stress, margins of safety, displacements and buckling.

Findings
The results obtained indicated a predominance of the use of carbon fiber. The predominant orientation found on the main spar flange was 0° with its location at 28% of the local chord, in the secondary and main web were ±45°, the skins also had the main orientation at ±45°.

Originality/value
The key innovations in this paper include the evaluation, development and optimization of a laminated composite structure applied to a LASER aircraft wings considering both structural performance and manufacturing costs in multiobjetive optimization. This paper is one of the most advanced investigations performed to composite LASER aircraft.
The relationship between autistic characteristics, social engagement and executive function in a typical sample
Authors: Robertson Nicolle , Qureshi Adam , Monk Rebecca L. 
Published: June 2021

Purpose
This study aims to represent a first attempt to examine in a non-clinical population the interplay between social engagement, executive function (EF) and theory of mind (ToM) within a social motivation theory framework.

Design/methodology/approach
A total of 170 participants (135 female; mean age = 19.01 and standard deviation = 1.27) completed measures of ToM (Faux Pas task), autistic traits (Autism Spectrum Quotient), social engagement (reward dependence subscale of the Temperament and Character Inventory), sociability and EF (both subscales of the Adult Temperament Questionnaire).

Findings
Path analyses found that EF, sociability and social engagement were negatively associated with autistic traits both directly and indirectly. Results indicate that EF may impact sociability and social engagement and their interaction may relate to the degree of autistic traits shown in a typical sample. However, ToM (as measured by the Faux Pas test) was not related to any of the other variables.

Originality/value
Sociability, social engagement and effortful control deficits may be linked to higher levels of autistic traits. These factors appear to form a hierarchy of factors underpinning autism spectrum disorder, with EF contributing to all aspects, followed by sociability and social engagement at a higher level. Future research examining in clinical populations the utility of a more integrated model of social motivation that incorporates EF appears warranted.
The impact of digital image-based features on users' emotions and online behaviours in the food industry
Authors: Murtarelli Grazia , Romenti Stefania , Valentini Chiara 
Published: June 2021

PurposeOnline images can convey sensory-based elements affecting digital users' emotions and digital engagement. The purpose of this study is to investigate which image-based features are more effective in conveying and stimulating particular emotions and engagement towards organizations operating in the food industry.Design/methodology/approachAn online experimental survey was implemented. Two image-based features, narrativity and dynamism were chosen. The stimuli comprise four images, one with high and one with low level of narrativity, and one with high and one with low dynamism, published by a food company on its official Instagram account. Food-identity, emotional appeals and digital visual engagement behaviours were measured. A total of 141 students between 19 and 25 years old of a European University completed the questionnaire. Data was analysed through SPSS software using t-test analysis.FindingsResults show that both narrativity and dynamism impact digital users' emotions and it was found to impact digital visual engagement attitude. Food involvement was measured in terms of food identity impact the effects of specific image-based features on emotions and visual engagement.Research limitations/implicationsThe study focuses on only two visual social semiotics features – narrativity and dynamism – and therefore, only partially captures the potentialities of images in digital communications.Practical implicationsThis study provides professionals with empirical evidence and insights for effectively planning a visual social media strategy.Originality/valueThis paper contributes to the stream of research in social media communications by investigating the visual social semiotic features of images published online by a food company.
Barriers to corporate social responsibility practices in construction and roles of education and government support
Authors: Pham Hai , Pham Tho , Dang Chau Ngoc 
Published: June 2021

PurposeThis study aims to empirically investigate the impact of barriers (i.e. organizational and industrial barriers, corporate social responsibility (CSR) characteristics) on CSR practices and the roles of education and government support in mitigating these barriers. In addition, the positive effect of CSR practices on social sustainability performance (SSP) is examined.Design/methodology/approachA framework of hypotheses between barriers, CSR practices and SSP is established. Using a survey questionnaire, empirical data are collected from 17 construction firms in Vietnam. PLS-SEM is used to test the proposed hypotheses.FindingsThe results indicate that organizational and industrial barriers negatively affect CSR practices. This study also finds that education and training and government support could enable construction firms to reduce the impact of such barriers.Research limitations/implicationsThe data are collected in Vietnam; thereby the findings are only applicable in developing countries. Further research should also be conducted in other countries to improve the generalizability of the theoretical framework.Practical implicationsThe findings of this study suggest that construction firms could apply several strategies (e.g. providing their employees with CSR training and education; embedding CSR into their firm policy, mission and vision) to mitigate the impact of CSR barriers and, accordingly, ensure the success of adopting CSR practices.Originality/valueThis study is one of the first efforts in the construction industry that empirically investigates the impact of barriers on CSR practices and the moderating effects of training and education as well as government support.
Stakeholders' impact on the leadership potential of small and medium-sized construction enterprises
Authors: Cai Xinyu , Gura Dmitry , Kurilova Anastasia 
Published: June 2021

PurposeThis study aimed to develop a methodological approach to assessing the impact of stakeholders on leadership potential of small and medium-sized construction enterprises.Design/methodology/approachThe research methodology was based on taxonomic analysis to determine the coefficient of leadership potential in the following areas: financial growth of an enterprise, internal processes, human resources development and market potential. The examination process was grounded on the materials from small and medium-sized construction companies located in Russia and China.FindingsSubgroups of companies with positive dynamics of indicators, an unstable situation and negative trends of leadership potential formation are identified. Russian small and medium-sized construction companies prioritize the development of sales policies and the management of internal business processes, while Chinese companies–human potential. The generated regression equations indicate a direct relationship between stakeholder engagement and the leadership potential of construction companies in both countries.Originality/valueThe scientific contribution of this study is the proposed methodological approach to assessing the development of the leadership potential of an enterprise and diagnosing the degree of stakeholders' influence on the latter. This is facilitated by comprehensive analysis, which includes an assessment of leadership potential based on the results of taxonomic analysis, construction of vector diagrams and regression analysis. This study can be useful for persons conducting research in the direction of small and medium-sized business management, forming a strategy for business development and competition policy to form a company's leadership position in the market.
The HEXACO, academic motivation and learning approaches: evidence from a central Asian country
Authors: Mahmood Monowar , Frolova Yuliya , Gupta Bhumika 
Published: June 2021

PurposePersonality traits are assumed to influence cognitive processes as well as academic motivation and learning approaches of the students. Based on these assumptions, the present study investigates the association of HEXACO personality traits with academic motivation as well as influence of those traits on students' learning approaches in educational contexts.Design/methodology/approachSelf-reported measures of personality orientation, academic motivation and learning approaches were obtained from 404 respondents in a classroom environment. The SPSS 20 software was used to conduct the correlations and the hierarchical regression analyses. The Eviews 10 software was used to develop the structural equation model to find the inter-relations among the study variables.FindingsThe findings reveal the influence of personality traits on academic motivation and learning approaches of the students. Among different personality traits, consciousness appeared to have highly positive impact on deep learning and intrinsic motivation of the studies. Neuroticism appeared to have most negative impact related to surface learning and amotivation of the learning contents.Research limitations/implicationsThe findings validates the existence of HEXACO personality traits among the students in central Asian context. It future reiterated individual differences in learning strategies and learning motivation among the learners. The results may help academics and policy makers take appropriate measures to increase academic motivation and select appropriate learning approaches.Originality/valueThis is one of the pioneer studies to investigate the relationship between HEXACO personality traits, learning strategies and academic motivation. Validation of the HEXACO framework will help to understand students' personality in a more detailed and elaborative way and will contribute to the existing literature on personality and learning outcomes.
Making finance fun: the gamification of personal financial management apps
Authors: Bitrián Paula , Buil Isabel , Catalán Sara 
Published: June 2021

PurposeThis study integrates self-determination theory (SDT) and the technology acceptance model (TAM) to explore how gamification increases users' motivation and intention to use personal financial management (PFM) apps, and how it facilitates their adoption.Design/methodology/approachData from 208 users of the Mint app were analyzed using partial least squares structural equation modeling.FindingsThe results showed that gamifying PFM apps satisfies users' needs for competence and autonomy and enhances their autonomous motivation to use them. Users' motivation increases their perceptions of ease of use and usefulness of the apps and causes them to develop more favorable attitudes toward them. The findings also confirmed a relationship between users' attitudes toward PFM apps and the behavioral intention to use them.Research limitations/implicationsTo investigate the generalizability of results, studies using other PFM apps would be useful. The cross-sectional nature of the research also limits its causal inference.Practical implicationsThis research provides support for the use of gamification in PFM apps and offers suggestions that may help fintech companies and banks to persuade users to engage with their apps.Originality/valueAlthough gamification is a trending topic, few studies have explored its use in the finance industry. Drawing on SDT and the TAM, this study extends previous research and adds new insights into the effects of gamification in this context.
Green HRM and nongreen outcomes: the mediating role of visionary leadership in Asia
Authors: Ismail Hussein , El Irani Miriam , Kertechian Kevin Sevag 
Published: June 2021

PurposeThe main purpose of this study was to test whether green human resource management (GHRM) practices affect employee nongreen outcomes through the mediation of perceived visionary leadership.Design/methodology/approachA sample of 144 Lebanese employees from the construction industry took part in this study. Multiple regression and bootstrapping methods were employed in the analysis of the data.FindingsGHRM was found to influence organizational pride and organizational citizenship behavior positively via visionary leadership. The results highlight the importance of implementing GHRM as a strategy to achieve environmental sustainability and enhance employee behaviors.Originality/valueThis is one of the first studies to explore the impact of GHRM on nongreen work outcomes in Western Asia, particularly Lebanon, in addition to exploring the mediating role of visionary leadership in the relationship between GHRM and nongreen work outcomes.
Investigating efficiency of frontier stock markets using multifractal detrended fluctuation analysis
Authors: Aslam Faheem , Ferreira Paulo , Mohti Wahbeeah 
Published: June 2021

PurposeThe investigation of the fractal nature of financial data has been growing in the literature. The purpose is to investigate the multifractal behavior of frontier markets using multifractal detrended fluctuation analysis (MFDFA).Design/methodology/approachThis study used daily closing prices of nine frontier stock markets up to 31-Aug-2020. A preliminary analysis reveals that these markets exhibit fat tails and clustering patterns. For a more robust analysis, a combination of Seasonal and Trend Decomposition using Loess (STL) and MFDFA has been employed. The former method is used to decompose daily stock returns, where later detected the long rang dependence in the series.FindingsThe results confirm varying degree of multifractality in frontier stock markets, implying that they exhibit long-range dependence. Based on these multifractality levels, Serbian and Romanian stock markets are the ones exhibiting least long-range dependence, while Slovenian and Mauritius stock markets indicating highest dependence in their series. Furthermore, the markets of Kenya, Morocco, Romania and Serbia exhibit mean reversion (anti-persistent) behavior while the remaining frontier markets show persistent behaviors.Practical implicationsThe information given by the detection of the fractal measure of data can support for investment and policymaking decisions.Originality/valueFrontier markets are of great potential from the perspective of international diversification. However, most of the research focused on other emerging and developed markets, especially in the context of multifractal analysis. This study combines the STL method and a physics-based robust technique, MFDFA to detect the multifractal behavior of frontier stock markets.
Equivalence of care? Accessibility and availability of dialysis services for older prisoners in Switzerland
Authors: Haesen Sophie , Rauch Sebastian , Elger Bernice , Rost Michael 
Published: June 2021

Purpose
According to the principle of equivalence of care, health care in prison has to be of the same standard and quality as in the general population. This study aims to determine the geographic accessibility of dialysis services for older prisoners and the older general population in Switzerland and whether accessibility and availability of dialysis care are equivalent.

Design/methodology/approach
Spatial accessibility analysis incorporated four different data types: population data, administrative data, street network data and addresses of prisons and hemodialysis services.

Findings
Analysis revealed that the average travel time to the nearest dialysis service was better for prisoners (11.5 min) than for the general population (14.8 min). However, dialysis service for prisoners is hampered by the necessary lead-time in correctional settings, which, ultimately, leads to longer overall access times (36.5 min). Accordingly, the equivalence of dialysis care for older Swiss prisoners is not entirely respected for availability and accessibility.

Originality/value
The strength of the study lies in the combination of ethical principles and the highly tangible results of a spatial accessibility analysis. The ethics-driven empirical analysis provides arguments for policy-makers to review the current practices.
Balancing online pharmacy services for patient adherence: a stimulus-organism-response perspective
Authors: Yang Hongze , Peng Zeyu , Guo Xitong , Lai Kee-Hung 
Published: June 2021

PurposeThe purpose of this study is to identify patient experience unique to online pharmacy services (OPS) based on the characteristics of OPS (i.e. interactivity and virtuality) and to reveal how patient experience is derived from OPS and thereby enhances patient adherence from both online social support and patient experience perspectives.Design/methodology/approachThe Stimulus-Organism-Response framework was used to conceptualize this study; both primary and secondary data for 296 validated participants were collected on a real OPS platform. A structural equation modeling approach combined with partial least squares was employed for the quantitative analysis.FindingsSocial presence and user engagement can be identified as patient experience in the OPS context; online emotional support has a stronger association with patients' social presence than it does with patients' user engagement; patients' social presence has a stronger association with their medication adherence than it does with diet adherence, while patients' user engagement has a stronger association with their diet adherence than it does with medication adherence; patients' medication knowledge negatively moderates the relationship between user engagement and diet adherence.Originality/valueThis study identifies patient experience in accordance with unique characteristics of OPS, and it reveals the nuanced underlying mechanisms by which online social support is associated with patient experience and by which patients' experience is associated with their adherence. This study enriches the literature on patient adherence, patient experience and OPS, providing insights for healthcare providers, OPS designers and policymakers.