bluuebunny/crossref_metadata_2025_split huggingface dataset:
Generic relationships of New World Jerusalem crickets (Orthoptera: Stenopelmatoidea:Stenopelmatinae), including all known species of Stenopelmatus
Authors: WEISSMAN DAVID B. , VANDERGAST AMY G. , SONG HOJUN , SHIN SEUNGGWAN , MCKENNA DUANE D. , UESHIMA NORIHIRO 
Published: January 2021

The New World Jerusalem crickets currently consist of 4 genera: Stenopelmatus Burmeister, 1838, with 33 named entities; Ammopelmatus Tinkham, 1965, with 2 described species; Viscainopelmatus Tinkham, 1970, with 1 described species, and Stenopelmatopterus Gorochov, 1988, with 3 described species. We redefine the generic boundaries of these 4 genera, synonymize Stenopelmatopterus under Stenopelmatus, and synonymize Viscainopelmatus under Ammopelmatus. We then discuss, and illustrate, all the types of the species of Stenopelmatus, all of which only occur south of the United States’ border. We recognize as valid the following 5 described Mexican and Central American species: S. ater, S. piceiventris, S. sartorianus, S. talpa, and S. typhlops. We declare the following 13 described Mexican and Central American Stenopelmatus taxa as nomen dubium: S. calcaratus, S. erythromelus, S. guatemalae, S. histrio, S. lessonae, S. lycosoides, S. mexicanus, S. minor, S. nieti, S. sallei, S. sumichrasti, S. toltecus, and S. vicinus. We designate a neotype for S. talpa and lectotypes for S. ater, S. guatemalae, S. histrio, S. lessonae, S. mexicanus, S. minor, S. nieti, S. sallei, S. sumichrasti, and S. toltecus. We assign a type locality for S. piceiventris. We concur with the previous synonymy of S. politus under S. sartorianus. We describe 14 new species of Stenopelmatus from Mexico, Honduras and Ecuador, based on a combination of adult morphology, DNA, calling song drumming pattern, distribution, and karyotype: S. chiapas sp. nov., S. cusuco sp. nov., S. diezmilpies sp. nov., S. durango sp. nov., S. ecuadorensis sp. nov., S. faulkneri sp. nov., S. honduras sp. nov., S. hondurasito sp. nov., S. mineraldelmonte sp. nov., S. nuevoleon sp. nov., S. perote sp. nov., S. saltillo sp. nov., S. sanfelipe sp. nov., and S. zimapan sp. nov. We transfer the following 16 described United States taxa, plus S. cephalotes from the “west coast of North America”, from Stenopelmatus to Ammopelmatus: A. cahuilaensis, A. californicus, A. cephalotes, A. fasciatus, A. fuscus, A. hydrocephalus, A. intermedius, A. irregularis, A. longispinus, A. mescaleroensis, A. monahansensis, A. navajo, A. nigrocapitatus, A. oculatus, A. pictus, and A. terrenus, along with the Mexican taxon A. comanchus: these species will be discussed in a subsequent paper (Weissman et al. in prep). We believe that all new Jerusalem cricket species descriptions should include, at a minimum, calling drum (most important) and DNA information.
Southward Cold Airmass Flux Associated with the East Asian Winter Monsoon: Diversity and Impacts
Authors: Liu Qian , Chen Guixing , Wang Lin , Kanno Yuki , Iwasaki Toshiki 
Published: January 2021

AbstractThe winter monsoon has strong impacts on East Asia via latitude-crossing southward cold airmass fluxes called cold air outbreaks (CAOs). CAOs have a high diversity in terms of meridional extent and induced weather. Using the daily cold airmass flux normalized at 50° and 30°N during 1958–2016, we categorize the CAOs into three groups: high–middle (H–M), high–low (H–L), and middle–low (M–L) latitude events. The H–L type is found to have the longest duration, and the M–L type is prone to strong CAOs regarding normalized intensity. The H–L and H–M events feature a large-scale dipole pattern of cold airmass flux over high-latitude Eurasia; the former events feature relatively strong anticyclonic circulation over Siberia, while the latter events feature cyclonic circulation over northeastern Asia. In contrast, the M–L events are characterized by a cyclonic anomaly over northeastern Asia but no obvious high-latitude precursor. The H–L events have the greatest cold anomaly in airmasses near the surface, and the M–L events mainly feature a strong northerly wind. As a result, the H–L events induce widespread long-lasting low temperatures over East Asia, while the M–L events induce a sharp temperature drop at mainly low latitudes. Both H–L and M–L events couple with the MJO to enhance rainfall over the South China Sea, while H–M events increase rainfall over southern China. Moreover, the occurrences of H–L and M–L events have experienced a long-term decrease since the 1980s that has induced a stronger warming trend in the cold extremes than in the winter mean temperature at mid–low latitudes over East Asia.
A review of movement disorders in chemotherapy-induced neurotoxicity
Authors: Wang Allison B. , Housley Stephen N. , Flores Ann Marie , Kircher Sheetal M. , Perreault Eric J. , Cope Timothy C. 
Published: January 2021

AbstractChemotherapy agents used in the standard treatments for many types of cancer are neurotoxic and can lead to lasting sensory and motor symptoms that compromise day-to-day movement functions in cancer survivors. To date, the details of movement disorders associated with chemotherapy are known largely through self-reported symptoms and functional limitations. There are few quantitative studies of specific movement deficits, limiting our understanding of dysfunction, as well as effective assessments and interventions. The aim of this narrative review is to consolidate the current understanding of sensorimotor disabilities based on quantitative measures in cancer survivors who received chemotherapy. We performed literature searches on PubMed and found 32 relevant movement studies. We categorized these studies into three themes based on the movement deficits investigated: (1) balance and postural control; (2) gait function; (3) upper limb function. This literature suggests that cancer survivors have increased postural sway, more conservative gait patterns, and suboptimal hand function compared to healthy individuals. More studies are needed that use objective measures of sensorimotor function to better characterize movement disabilities and investigate the underlying causes, as required for developing targeted assessments and interventions. By updating our understanding of movement impairments in this population, we identify significant gaps in knowledge that will help guide the direction of future research.
Performance of age-adjusted D-dimer values for predicting DVT before the knee and hip arthroplasty
Authors: Wu Jian Xiang , Qing Jiang Hui , Yao Yao , Chen Dong Yang , Jiang Qing 
Published: January 2021

Abstract
Purpose
To compare the specificity and sensitivity of preoperative D-dimer and age-adjusted D-dimer value for predicting the incidence of the DVT preoperatively in total joint arthroplasty (TJA) patients.

Methods
We enrolled 406 patients finally above 50 years old. Everyone had done ultrasonography bedside, and D-dimer concentrations were collected before surgery. The D-dimer and age-adjusted D-dimer cut-off was calculated by multiple logistic regression and receiver operating curve (ROC) analyses.

Results
A total of 39 patients had found asymptomatic deep vein thrombosis (DVT) by ultrasonography. The age (odds ratio [OR] 1.067; p = 0.003) and D-dimer (OR 1.331; p = 0.025) were related to the existence of DVT. For conventional D-dimer and age-adjusted D-dimer value, the area under the curves (AUCs) were 0.685 (0.499–0.696) and 0.795 (0.611–0.881), respectively.

Conclusion
Compared to traditional D-dimer, age-adjusted D-dimer showed better performance in screening DVT, which was useful clinically.
Targeted eicosanoids profiling reveals a prostaglandin reprogramming in breast Cancer by microRNA-155
Authors: Kim Sinae , Lee Eun Sung , Lee Eun ji , Jung Jae Yun , Lee Sae Byul , Lee Hee Jin , Kim Jisun , Kim Hee Jeong , Lee Jong Won , Son Byung Ho , Gong Gyungyub , Ahn Sei-Hyun , Chang Suhwan 
Published: January 2021

Abstract

Background
Prostaglandin is one of the key metabolites for inflammation-related carcinogenesis. Despite the microRNA-155 is implicated in various types of cancers, it’s function in prostaglandin metabolism is largely unknown.

Methods
A targeted profiling of eicosanoids including prostaglandin, leukotriene and thromboxanes was performed in miR-155 deficient breast tumors and cancer cells. The molecular mechanism of miR-155-mediated prostaglandin reprogramming was investigated in primary and cancer cell lines, by analyzing key enzymes responsible for the prostaglandin production.

Results
We found miR-155-deficient breast tumors, plasma of tumor-bearing mouse and cancer cells show altered prostaglandin level, especially for the prostaglandin E2 (PGE2) and prostaglandin D2 (PGD2). Subsequent analysis in primary cancer cells, 20 triple-negative breast cancer (TNBC) specimens and breast cancer cell lines with miR-155 knockdown consistently showed a positive correlation between miR-155 level and PGE2/PGD2 ratio. Mechanistically, we reveal the miR-155 reprograms the prostaglandin metabolism by up-regulating PGE2-producing enzymes PTGES/PTGES2 while down-regulating PGD2-producing enzyme PTGDS. Further, we show the up-regulation of PTGES2 is driven by miR-155-cMYC axis, whereas PTGES is transactivated by miR-155-KLF4. Thus, miR-155 hires dual-regulatory mode for the metabolic enzyme expression to reprogram the PGE2/PGD2 balance. Lastly, we show the miR-155-driven cellular proliferation is restored by the siRNA of PTGES1/2, of which expression also significantly correlates with breast cancer patients’ survival.

Conclusions
Considering clinical trials targeting PGE2 production largely have focused on the inhibition of Cox1 or Cox2 that showed cardiac toxicity, our data suggest an alternative way for suppressing PGE2 production via the inhibition of miR-155. As the antagomiR of miR-155 (MRG-106) underwent a phase-1 clinical trial, its effect should be considered and analyzed in prostaglandin metabolism in tumor.
Acetate Ringer’s solution versus 0.9% saline for septic patients: study protocol for a multi-center parallel controlled trial
Authors: Liu Fang , Zhang Jing , Zhu Yuan , Su Lianjiu , Li Yiming , He Li , Yu Li , Peng Zhiyong 
Published: January 2021

AbstractBackgroundPrevious study drew different conclusions on significant differences between saline and balanced crystalloid solution infused in critical illness but both showed a statistical difference in the sepsis subgroup. Thus, we will specifically focus on septic patients in this study to compare the effects of saline and balanced solution. We hypothesize that effects of saline on renal outcomes are related to the underline acute kidney injury (AKI) severity and total volumes of infusion.Methods/designThe investigators designed a pragmatic, multi-center parallel controlled trial recruiting 312 patients who are diagnosed with sepsis/septic shock in the intensive care unit (ICU) and will be assigned with either acetate Ringer’s solution or saline in the corresponding month. Patients with an end-stage renal disease (ESRD) or who need renal replacement therapy (RRT) prior to or at the time of enrolment are excluded. Enrolled patients will be regarded as with mild, moderate, or severe sepsis on the basis of the severity of their illness and will be divided into subgroups according to their initial renal function and various intravenous infusion volumes when being analyzed. The primary outcome is major adverse kidney events within 28 days (MAKE28), including the composite of in-hospital death, receipt of new renal replacement therapy, or persistent renal dysfunction. Secondary outcomes include 28-day mortality, internal environment disturbance, incidence and duration of vasoactive drug treatment, duration of mechanical ventilation, duration of RRT, and ICU and hospital length of stay.Results and conclusionsTo our knowledge, this study will be the first to focus on septic patients and provide credible and evident data on the comparison of outcome between acetate Ringer’s solution and saline for intravenous infusion in adult septic patients on the basis of baseline renal function and infusion volumes taken into consideration.Trial registrationClinicalTrials.govNCT03685214. Registered on August 15, 2018
Rapid four-component synthesis of dihydropyrano[2,3-c]pyrazoles using nano-eggshell/Ti(IV) as a highly compatible natural based catalyst
Authors: Dehghani Tafti Arefeh , Mirjalili Bi Bi Fatemeh , Bamoniri Abdolhamid , Salehi Naeimeh 
Published: January 2021

AbstractNano-eggshell/Ti(IV) as a novel naturally based catalyst was prepared, characterized and applied for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives. The characterization of nano-eggshell/Ti(IV) was performed using Fourier Transform Infrared spectroscopy, X-ray Diffraction, Field Emission Scanning Electron Microscopy, Energy-Dispersive X-ray Spectroscopy, and Thermo Gravimetric Analysis. Dihydropyrano[2,3-c]pyrazoles were synthesized in the presence of nano-eggshell/Ti(IV) via a four component reaction of aldehydes, ethyl acetoacetate, malononitrile and hydrazine hydrate at room temperature under solvent free conditions. The principal affairs of this procedure are mild condition, short reaction times, easy work-up, high yields, reusability of the catalyst and the absence of toxic organic solvents.
Dynamic out-of-vocabulary word registration to language model for speech recognition
Authors: Kitaoka Norihide , Chen Bohan , Obashi Yuya 
Published: January 2021

AbstractWe propose a method of dynamically registering out-of-vocabulary (OOV) words by assigning the pronunciations of these words to pre-inserted OOV tokens, editing the pronunciations of the tokens. To do this, we add OOV tokens to an additional, partial copy of our corpus, either randomly or to part-of-speech (POS) tags in the selected utterances, when training the language model (LM) for speech recognition. This results in an LM containing OOV tokens, to which we can assign pronunciations. We also investigate the impact of acoustic complexity and the “natural” occurrence frequency of OOV words on the recognition of registered OOV words. The proposed OOV word registration method is evaluated using two modern automatic speech recognition (ASR) systems, Julius and Kaldi, using DNN-HMM acoustic models and N-gram language models (plus an additional evaluation using RNN re-scoring with Kaldi). Our experimental results show that when using the proposed OOV registration method, modern ASR systems can recognize OOV words without re-training the language model, that the acoustic complexity of OOV words affects OOV recognition, and that differences between the “natural” and the assigned occurrence frequencies of OOV words have little impact on the final recognition results.
Guangzhou Tongcao painting in late China Qing Dynasty (1840–1912 AD): technology revealed by analytical approaches
Authors: Zhang Chan , Huang Jianbin , Zhu Tiequan , Zhang Rongling 
Published: January 2021

Abstract
Guangzhou Tongcao paintings in Qing Dynasty of China witnessed the exchange of economy, culture, art and technology between China and foreign countries, which were an important export product in historical China. In this paper, by using Optical Stereo Microscope, Polarized Light Microscope, Scanning Electron Microscope attached Energy Dispersive Spectroscopy and micro confocal laser Raman Spectroscope, a Qing Dynasty Tongcao painting with the subject of family life of an official’s female relative was analyzed. Our study revealed that: (1) the hexagonal cell morphology which was easily observed in the Tongcao pith could contain more pigments and increase the stereo sense of painting, and the cell of historical Tongcao pith had started to degrade, which indicated an urgent requirement on conservation of Tongcao paintings; (2) alum was needed as the fixing agent in the preparation of pigments and the painting process; (3) both the China domestic pigments including red lead, calcite, lead white, carbon black and gamboge, and the synthetic pigments imported from Europe (synthetic ultramarine, prussian blue and emerald green) were applied in this painting, which reflected the bi-directional communication of culture and technology between China and western world. Meanwhile, the existence of synthetic ultramarine, prussian blue and emerald green was helpful to further identify the production date of this painting was late Qing Dynasty, mainly the mid-late 19th century.
Determinants of consumer attitudes and re-purchase intentions toward direct-to-consumer (DTC) brands
Authors: Kim Naeun Lauren , Shin Daeun Chloe , Kim Gwia 
Published: January 2021

AbstractIn the fashion and retail industry, a group of startups, referred to as Direct-to-Consumer (DTC) brands, are proliferating. DTC brands are defined as e-commerce brands that sell directly to consumers, without retailer ‘middlemen’ like department stores. They typically begin as a purely online business, fully leveraging digital channels for marketing and selling. Given the limited research on the topic, this paper aims to identify determinants of consumers’ attitudes and re-purchase intentions toward DTC brands. The initial qualitative phase of in-depth interviews with frequent DTC shoppers, resulted in the identification of eight determinants. The subsequent quantitative analysis with 210 US DTC shoppers confirmed that co-creation, cost-effectiveness, website attractiveness, brand uniqueness, social media engagement, and innovativeness of DTC brands significantly influence consumers’ attitudes while cost-effectiveness (indirectly), brand uniqueness, social media engagement, and brand innovativeness affect consumers re-purchase intentions. The findings offer insights for aspiring entrepreneurs and incumbent retailers on strengthening their value propositions.
A case of gastric and duodenal mucosa-associated lymphoid tissue lymphoma with multiple gastric cancers: a case report
Authors: Yokoyama Takashi , Tanaka Tetsuya , Harada Suzuka , Ueda Takeshi , Ejiri Goki , Sasaki Shoh , Takeda Maiko , Yoshimura Atsushi 
Published: January 2021

Abstract
Background
Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is often caused by Helicobacter pylori and has a good prognosis. Rarely, patients with MALT lymphoma may have gastric cancer and have a poor prognosis.

Case presentation
We herein report a case in which surgical treatment was achieved for a 72-year-old male patient with gastric and duodenal MALT lymphoma coexisting multiple gastric cancers. He underwent upper endoscopy for epigastric discomfort, which revealed mucosal erosion on the posterior wall of the middle body of the stomach, an elevated lesion on the duodenal bulb, and a raised tumor on the antrum of the stomach. He was diagnosed with gastric and duodenal MALT lymphoma with early gastric cancer. One month after H. pylori eradication, a second upper endoscopy revealed no improvement in the gastric or duodenal mucosa, and areas of strong redness with a shallow recess just below the cardia of the stomach. As a result, a diagnosis of gastric and duodenal MALT lymphoma with two gastric cancers was made. Total gastrectomy with proximal duodenum resection using intraoperative upper endoscopy and regional lymph node dissection was performed. Pathologically, gastric and duodenal MALT lymphoma and three gastric cancers were detected. Since one of them was an advanced cancer, he started taking S-1 after his general condition improved.

Conclusion
For early detection of gastric and duodenal MALT lymphoma or gastric cancer, appropriate upper endoscopy and a biopsy are important. It is necessary to select a suitable treatment, such as H. pylori eradication, endoscopic treatment, surgery, chemotherapy, and irradiation, according to the disease state.
Governing displaced migration in Europe: housing and the role of the “local”
Authors: Meer Nasar , Dimaio Claudio , Hill Emma , Angeli Maria , Oberg Klara , Emilsson Henrik 
Published: January 2021

AbstractThis article will explore the extent to which a focus on the ‘local’ can tell us something meaningful about recent developments in the governance of displaced migrants and refugees. Taking a multi-sited approach spanning cases in the south and north of Europe, we consider how the challenge of housing and accommodation in particular, a core sector of migrant reception and integration, can shed light on the ways local and city level approaches may negotiate, and sometimes diverge from, national level policy and rhetoric. While it can be said that despite variation, local authorities are by definition ultimately ‘always subordinate’ (Emilsson, Comparative Migration Studies, 3: 1-17, 2015: 4), they can also show evidence of ‘decoupling’ across geographies of policy delivery (Pope and Meyer, European Journal of Cultural and Political Sociology, 3: 280–305, 2016: 290). This article traces how possible local variations in different European cases are patterned by ground-level politics, local strategic networks, and pre-existing economic resources in a manner that is empirically detailed through the study of housing.
HSV-pneumonitis in a patient with lung cancer receiving check point inhibitors – a case report
Authors: Sumer Johannes , Waldeck Frederike , Fischer Nadja , Appenzeller Christina , Koster Markus , Früh Martin , Albrich Werner C. 
Published: January 2021

Abstract
Background
Herpes simplex virus (HSV) is commonly associated with oro-facial and genital manifestations. It rarely causes encephalitis and even less commonly, in heavily immunosuppressed patients, visceral disease or bronchopneumonitis. We present a case of cytologically-proven, PCR-positive HSV-1 tracheobronchitis and pneumonitis in a patient with less severe immunocompromise.

Case presentation
A 64 year old white man with steroid-induced diabetes mellitus and progressive small-cell bronchial carcinoma despite chemo- and immunotherapy with two checkpoint inhibitors presented with symptoms of lower respiratory tract infection. Community-acquired pneumonia was suspected and empirical broad-spectrum antibacterial treatment was initiated. Chest CT-scan revealed ground-glass opacities and tree-in bud lesions. Cytology of BAL showed extensive cytopathic effects typically caused by infection with herpes virus and PCR confirmation of HSV-1. Acute phase HSV serology was positive for IgG and borderline for IgM. The patient deteriorated clinically due to tumor progress and infection despite high-dose acyclovir therapy and died 2 weeks after admission.

Conclusions
We report an unusual case of fatal HSV-1 pneumonitis due to reactivation in a patient with lung cancer, steroid-induced diabetes and treatment with two checkpoint inhibitors. In immunosuppressed patients with non-improving pneumonia invasive diagnostic procedures are warranted including cytology and molecular diagnostics.