bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti-inflammatory effect of neo-lignan isoamericanin A via suppression of NF-κB in liposaccharide-stimulated RAW 264.7 cells
Authors: Yeo Ji Yun , Hwang Kwang Woo , Park So-Young 
Published: January 2021

Purpose: To investigate the potential anti-inflammatory effects of the seeds of Opuntina humifusa and its active constituents.Methods: The extract of O. humifusa seeds was tested for the inhibition of nitric oxide (NO) production in liposaccharide (LPS)-stimulated RAW 264.7 cells using Griess reagent. The active constituents were isolated using bioassay-guided isolation methods. The effects of the active constituent on NO, proinflammatory cytokines, nuclear factor-kappa B (NF-κB) and nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor (IκB) were evaluated by enzyme-linked immunosorbent assay (ELISA) and western blot analysis.Results: The seed extract of O. humifusa significantly attenuated LPS-induced NO production in RAW 264.7 cells (p < 0.05). Bioassay-guided fractionation resulted in the isolation of isoamericanin A as an active constituent. Isoamericanin A reduced LPS-induced production of NO, iNOS, and proinflammatory cytokines (TNF-α and IL-6) in a concentration-dependent manner (p < 0.05). Furthermore, the effect was accompanied by decreased translocation of NF-κB from the cytosol to the nucleus and the decreased phosphorylation of IκB in the cytosol induced by LPS (p < 0.05).Conclusion: The seed extract of O. humifusa and its active constituent, isoamericanin A, have antiinflammatory effects in LPS-stimulated RAW 264.7 cells, suggesting that they have potentials as antiinflammatory agents.
Keywords: Opuntia humifusa seeds, Isoamericanin A, Nitric oxide, RAW 264.7 cells, NF-kappa B
NGHIÊN CỨU THỰC NGHIỆM GIA CÔNG TINH BỀ MẶT KHUÔN BẰNG SÓNG SIÊU ÂM
Authors: ĐỨC NAM NGUYỄN 
Published: January 2021

Các khuôn ép được sử dụng rộng rãi trong công nghiệp để chế tạo các chi tiết từ nhiều vật liệu khác nhau như nhựa, kim loại, cao su, kính, và các chất vô cơ khác. Chất lượng sản phẩm được tạo ra phụ thuộc rất lớn vào chất lượng bề mặt của khuôn. Do bề mặt khuôn có nhiều hình dạng phức tạp nên việc gia công tinh các bề mặt này gặp nhiều khó khăn. Để nâng cao độ nhám bề mặt của khuôn thì trong nghiên cứu này ứng dụng sóng siêu âm kết hợp với dung dịch mài để tiến hành mài tinh bề mặt. Các thông số ảnh hưởng đến quá trình gia công như kích thước hạt mài, nồng độ dung dịch hạt mài được khảo sát trong bài báo này. Dựa trên kết quả thực nghiệm, quá trình mài tinh bằng sóng âm kết hợp với dung dịch mài cải thiện đáng kể chất lượng bề mặt gia công, nâng cao hiệu quả của quá trình mài tinh bề mặt phức tạp. Kết quả cho thấy rằng, độ nhám bề mặt chi tiết từ Ra = 120 nm giảm xuống còn Ra = 32 nm và hiệu suất gia công tăng lên.
PHÂN TÍCH CÁC THÔNG SỐ CHÍNH CỦA CHU TRÌNH LẠNH MỘT CẤP SỬ DỤNG MÔI CHẤT R22/R410A/R32 BẰNG PHẦN MỀM MATLAB/SIMULINK
Authors: VIỆT HÙNG TRẦN , QUANG PHÚ PHẠM 
Published: January 2021

Bài viết trình bày kết quả mô phỏng của chu trình lạnh một cấp sử dụng máy nén hơi, các thông số của môi chất và thông số của chu trình lạnh khi sử dụng môi chất lạnh R22, R410A và R32 dựa trên phần mềm Matlab/Simulink. Hệ thống được mô phỏng với năng suất lạnh 9000 BTU/h (2,638 kW), nhiệt độ bay hơi 50C và nhiệt độ ngưng tụ 400C. Quá trình mô phỏng đã xác định được thông số trạng thái của môi chất lạnh và ảnh hưởng của nhiệt độ đến các thông số chu trình lạnh một cấp. Kết quả mô phỏng đạt được khi ở cùng điều kiện nhiệt độ hoạt động và năng suất lạnh tương đương thì thể tích hút của máy nén sử dụng môi chất R22 lớn hơn 31%, 37% so với R410A/R32 và hệ số hiệu quả năng lượng COP 5,581 (R22)/5,177 (R410A)/5,396 (R32).
NGHIÊN CỨU THIẾT KẾ MÁY HỦY GIẤY KIỂU MỚI SỬ DỤNG CHO PHÒNG KHẢO THÍ VÀ ĐẢM BẢO CHẤT LƯỢNG TẠI CÁC CƠ SỞ ĐÀO TẠO
Authors: HOÀNG MINH ĐẶNG , VĂN BÌNH PHÙNG , VIỆT ĐỨC NGUYỄN , QUỐC THẮNG HUỲNH , THANH VŨ NGUYỄN 
Published: January 2021

Hiện nay ở Việt Nam nhu cầu sử dụng máy để hủy giấy tờ tài liệu tại nhiều cơ quan xí nghiệp và đặc biệt tại các cơ sở giáo dục và đào tạo đang ngày càng gia tăng. Bài báo này đã tiến hành phân tích các ưu-nhược điểm của các loại máy hủy giấy trên thị trường hiện nay sử dụng cho văn phòng và công nghiệp. Trên cơ sở đó, các tác giả đã đề xuất một giải pháp về cơ chế hủy giấy mới dựa trên sự phân tích cấu tạo, so sánh, đánh giá tính năng, ưu điểm cùng các vấn đề kỹ thuật cần giải quyết, nhằm ứng dụng phù hợp với điều kiện tại phòng khảo thí và đảm bảo chất lượng ở các cơ sở giáo dục và đào tạo. Phương án được đề xuất hứa hẹn sẽ chế tạo ra một loại máy hủy giấy kiểu mới đáp ứng tối đa nhu cầu sử dụng tại các cơ sở này, đồng thời đóng góp vào công ngiệp xử lý giấy nói riêng và vấn đề môi trường của đất nước nói chung.
A Calculus of Interfaces for Distributed Collaborative Systems: The Guarded Attribute Grammar Approach
Authors: Badouel Eric , Djeumen Djatcha Rodrigue Aimé 
Published: January 2021

We address the problem of component reuse in the context of service-oriented programming and more specifically for the design of user-centric distributed collaborative systems modelled by Guarded Attribute Grammars. Following the contract-based specification of components we devel-opp an approach to an interface theory for the components of a collaborative system in three stages: we define a composition of interfaces that specifies how the component behaves with respect to its environement, we introduce an implementation order on interfaces and finally a residual operation on interfaces characterizing the systems that, when composed with a given component, can complement it in order to realize a global specification.
Nous abordons le problème de la réutilisation des composants dans le contexte de la programmation orientée services et plus spécifiquement pour la conception de systèmes collaboratifs distribués centrés sur l'utilisateur modélisés par des grammaires attribuées gardées. En suivant la démarche de la spécification contractuelle des composants, nous développons une approche de la théorie des interfaces pour les composants d'un système collaboratif en trois étapes: on définit une composition d'interfaces qui spécifie comment le composant se comporte par rapport à son environnement, on introduit un ordre d'implémentation sur les interfaces et enfin une opération de résidus sur les interfaces qui caractérise les systèmes qui, lorsqu'ils sont composés avec un composant donné, peuvent le compléter afin de réaliser une spécification du système global.
Democracia digital y administración pública en una municipalidad distrital
Authors: Aspillaga Muñoz Francisco , Piminchumo Mendez Andrea 
Published: January 2021

En la última década la democracia digital se ha convertido en un reto para el país y sus diversas instituciones a fi n de buscar la trasparencia y gestión ágil de recursos en la administración pública. Es así que la presente investigación tuvo como propósito, determinar cómo la democracia digital genera valor público en la administración pública en la Municipalidad Distrital de Picsi, 2019. El estudio tuvo alcance correlacional y se aplicó una metodología de naturaleza cuantitativa. La población de estudio se compuso por un total de 25 colaboradores de la Municipalidad Distrital de Picsi, Chiclayo – Lambayeque. La selección muestral fue no probabilística por conocimiento e interés del investigador, compuesta por toda la población, llamada también muestra universal de 25 colaboradores. La técnica de captación de datos fue la encuesta, y se construyeron dos instrumentos operativos para ello, los cuales fueron: el cuestionario sobre democracia digital y cuestionario sobre administración pública. Los resultados conseguidos determinaron que existe una vinculación altamente signifi cativa directa entre democracia digital y administración pública; ya que se ha registrado un coefi ciente de correlación de Rho Spearman de r=0,983** que señala que, a un alto nivel de democracia digital, le concierne un alto nivel de administración pública o a un bajo nivel de democracia digital, le concierne un bajo nivel de administración pública. Como conclusión es necesario promover actividades centradas en la democracia digital en los colaboradores de la Municipalidad Distrital de Picsi, 2019.
Precipitação provável e veranicos no Vale do Jequitinhonha-MG
Authors: Lacerda Matheus Gobira , Brito Bruna Laíz Nogueira , Lima Vico Mendes Pereira 
Published: January 2021

O conhecimento da variação e da distribuição das precipitações permite determinar períodos críticos predominantes numa determinada região e reduzir consequências causadas pelas flutuações do regime pluviométrico. Vários modelos de distribuição de frequência têm sido utilizados, visando à estimativa da precipitação provável para diferentes locais e períodos de ocorrência. No presente trabalho os dados de registros pluviométricos do município de Jequitinhonha, entre 1977 a 2002, foram utilizados para adequação dos modelos de distribuição de probabilidades. Os registros pluviométricos dos anos de 1950 a 2019, da mesma estação, foram utilizados para comparar as precipitações prováveis aos dados históricos e verificar a ocorrência de veranicos. Considerando o nível de probabilidade de 75%, verificou-se uma precipitação provável no período chuvoso (novembro a março) de 70,6 mm e no período seco (abril a outubro) de 13,7 mm. No mês de dezembro, com 75% de probabilidade de ocorrência, é esperada uma lâmina de 114 mm. A irregular distribuição das chuvas e a severidade dos veranicos nos anos de 2015 a 2019 resultou em perda de produção de grãos, diminuição da segurança alimentar e desabastecimento das famílias.
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Sistem Pendukung Keputusan Pemilihan Laptop Menggunakan Metode Topsis
Authors: Lie Fei , Suryosuseno Tjahjaning Tingastuti 
Published: January 2021

Competition in the banking sector requires every bank to compete to make types of credit products that are able to attract customers to want to transact with banks. Marketing with a product centric strategy needs to be combined with a customer centric to keep Customer Relationship Management in good order with customers. Customer identity can be used to realize the concept of a customer centric marketing strategy. This study describes the role of Data Mining on customer data accompanied by the application of Decision Tree techniques with the C4.5 algorithm to identify the most influential fields in predicting loan products.
The customer data fields used in this study include total balance, date of birth, occupation, and status. Selection of fields based on the terms and conditions that apply to each type of loan. The results of applying the C4.5 algorithm to customer data in the formation of loan product prediction decision trees show that the work attribute is the dominant attribute (highest Gain value) among the other attributes. Prediction results are validated with Confusion Matrix with an accuracy value for loan product prediction of 82%.
The results of this study concluded that the customer database is a source of data in the prediction process of loan products to be offered to customers, which can be used to support the marketing of bank loan products with a customer centric orientation.
Spiritualitas Hana Menurut 1 Samuel 1:1-28 Dan Implementasinya Bagi Wanita
Authors: Agustina20 Dian , Pattinama Yenny Anita , Harefa Febriaman Lalaziduhu 
Published: January 2021

Spiritualitas adalah hidup menurut roh. Dalam konteks hubungan yang transenden, roh itu adalah Roh Allah sendiri. Spiritualitas adalah hidup yang didasarkan pada pengaruh dan bimbingan Roh Allah. Spiritualitas bertujuan untuk membuat manusia hidup sesuai dengan cita-cita Allah atau tujuan Allah. Spiritualitas merupakan peningkatan hidup beragama yang bersumber pada religiositas. Dengan menghayati spiritualitas, manusia menjadi orang spiritual, yaitu orang yang menghayati Allah dalam hidup nyata sehari-hari sesuai dengan panggilan dan peran hidupnya. Untuk menemukan jawabannya, maka dibuatlah sebuah penelitian dengan menggunakan metode penelitian deskriptif bibliologis. Hasilnya adalah kaum wanita Kristen akan tekun mencari Tuhan, mengandalkan Tuhan, menjaga kekudusan hidup dan setia menepati janji.
Spirituality is living according to the spirit. In the context of a transcendent relationship, that spirit is the Spirit of God Himself. Spirituality is a life based on the influence and guidance of the Spirit of God. Spirituality aims to make human beings live according to God's ideals or God's purposes. Spirituality is an increase in religious life which is rooted in religiosity. By living spirituality, humans become spiritual people, that is, people who live God in real everyday life according to their vocation and role. To find the answer, a study was made using descriptive bibliological research methods. The result is that Christian women will diligently seek God, rely on God, keep their lives holy and faithfully keep their promises.
Perempuan Yang Bersyukur Menurut Alkitab Dan Implementasinya Bagi Kaum Wanita Hedonis
Authors: Sihombing Elisa , Paath Jean 
Published: January 2021

ABSTRAK
Perempuan yang bersyukur saat ini menjadi sebuah situasi yang sulit dilakukan oleh wanita dalam hidupnya. Kaum wanita hedonis karena tidak hanya merugikan secara rohani, namun juga karakter dan kepribadian individu. Oleh sebab itu penerapan perempuan bersyukur menurut Alkitab sangat penting bagi wanita yang hedonis dan tidak bersyukur dengan melalui pemahaman Firman Tuhan yang benar, mengetahui hakikatnya sebagai umat Allah. Firman Tuhan merupakan kebenaran yang akan menuntun orang percaya untuk serupa dengan Kristus Yesus. Kaum wanita hedonis yang tidak bersyukur telah terjadi di berbagai kalangan. Ini merupakan situasi yang memprihatikan, penurunan kualitas secara rohani, dan moral tentunya akan berpengaruh terhadap gereja. Berangkat dari problematika tersebut, jelas bahwa wanita hedonis sangat membahayakan. Dengan pendekatan kualitatif dan metode deskriptif-theologis dalam skripsi ini penulis memberikan implementasi bagi kaum wanita hedonis, sehingga hasil studi ini dapat menjadi acuan bagi kaum wanita dalam meningkatkan kualitas rohaninya.

ABSTRACT
Today a grateful woman is a situation that is difficult for women to do in her life. Women are hedonistic because they are detrimental not only spiritually, but also individual character and personality. Therefore, the application of women who are grateful according to the Bible is very important for women who are hedonistic and ungrateful by understanding the true Word of God, knowing their essence as God's people. God's Word is the truth that will lead believers to be like Christ Jesus. Hedonist women who are not grateful have occurred in various circles. This is a situation of concern, spiritual and moral deterioration will certainly affect the church. Departing from these problems, it is clear that hedonistic women are very dangerous. With a qualitative approach and descriptive-theological methods in this thesis, the authors provide an implementation for hedonic women, so that the results of this studycan be a reference for women in improving their spiritual quality.The second abstract is written in English. Abstract length maximum 250 words. At least the abstract should include the background of the study, research methods, research results and recommendations. The abstract should include two to five keywords, and the format of writing follows the template.
Konsep Kesatuan Yesus dan Allah Bapa Dalam Injil Yohanes 17:22 Untuk Menghadapi Doktrin Subordinansi Tritunggal Saksi Yehuwa
Authors: Manafe Yanjumseby Yeverson , Pattinama Yenny Anita 
Published: January 2021

Doktrin Trinitas atau doktrin Allah Tritunggal adalah pengajaran tentang Allah yang menyatakan diri-Nya dalam tiga pribadi, yaitu Allah Bapa, Allah Anak (Yesus Kristus), dan Allah Roh Kudus yang ketiganya adalah esa. Di satu sisi, doktrin tersebut merupakan doktrin yang sangat penting dan unik dalam kekristenan. Dikatakan penting karena doktrin ini berbicara tentang Allah Tritunggal yang menjadi pusat pujian, penyembahan dan pelayanan orang percaya. Dikatakan unik karena doktrin tersebut tidak terdapat dalam agama manapun di dunia ini. Namun, di sisi lain, doktrin tersebut merupakan doktrin yang sulit dipahami dan diterima oleh akal manusia bahkan menjadi bahan perdebatan yang hebat di berbagai tempat, masa dan kalangan manusia. Dengan studi eksegetis Yohanes 17: 22 sebagai dasar evaluasi kritis terhadap doktrin subordinasi Tritunggal dalam theologia Saksi Yehuwa, maka dapat diketahui bahwa doktrin subordinasi Tritunggal dalam theologia Saksi Yehuwa adalah doktrin yang menyimpang dari kebenaran Alkitab.
The doctrine of the Trinity or the doctrine of the Triune God is the teaching of God revealing Himself in three persons, namely God the Father, God the Son (Jesus Christ), and God the Holy Spirit of which all three are one. On the one hand, the doctrine is a doctrine that is very important and unique in Christianity. It is said to be important because this doctrine speaks of the triune God who is the center of the worship, worship and service of believers. Said to be unique because the doctrine does not exist in any religion in this world. However, on the other hand, the doctrine is a doctrine that is difficult to understand and accepted by human reason and even becomes a matter of great debate in various places, times and circles of humans. With the exegetical study of John 17: 22 as the basis for a critical evaluation of the doctrine of the subordination of the Trinity in the theology of Jehovah's Witnesses, it can be seen that the doctrine of the subordination of the Trinity in the theology of Jehovah's Witnesses is a doctrine that deviates from Bible truth.
Prevalence of nonsuicidal Self-injury and Suicide Attempt among Young Adult university Students
Authors: Galicia Jhun Robbie U. , Bautista Tomas D. 
Published: January 2021

Objective. To determine the prevalence and possible risk factors associated with nonsuicidal self-injury (NSSI) and suicide attempt among young adult university students.
Methods. A cross-sectional study involving six colleges from a university in Manila, from which randomization through a computer-generated random number was done. Data were obtained through self-administered questionnaires. Descriptive analysis and logistic regression were done to evaluate the data.
Results. A total of 225 students participated in the study (mean age of 20.33 years). Majority were females (60.44%). Ideations of self-harm were reported in 49.33%. NSSI and suicide attempts were reported at 26.22% and 14.67%, respectively. In general, self-harm (NSSI and/or suicidal attempt) was reported at 33.78%, while 7.11% of the respondents reported both NSSI and suicidal attempt in the past. Furthermore, 2-3 out of 10 students who engaged in NSSI would have a suicide attempt. Associated factors of NSSI and suicide attempt were age, female gender, gender orientation, parental civil status, employment, economic standing, and psychopathology which support the findings cited in literature.
Conclusion. The high prevalence of self-harm NSSI and/or suicidal attempt (33.78%) and the finding that NSSI was a gateway for suicidal attempt and that 2-3 out of ten who engaged in NSSI would have a suicide attempt underscores the need to develop an early intervention upon detecting self-harming behaviors and a preventive program for the progression of NSSI to suicide attempts.
A Systematic Approach to Stillbirth Examination in a tertiary Hospital
Authors: Igualada Arby Jane R. , Domingo Efren J. , Avila Jose Maria C. 
Published: January 2021

Background. Stillbirth has a complex pathophysiology, hence the difficulty in arriving at a specific cause.
Objectives. The study aimed to identify the probable causes of stillbirth in a tertiary hospital based on gross examination of the placenta and the fetus, as well as, to identify the demographic profile of the stillbirths.
Methods. A cross-sectional descriptive study was conducted among 29 stillbirths delivered in a tertiary hospital from March 2016 to September 2016. The probable causes of stillbirth were categorized as obstetrics complications, placental abnormalities, umbilical cord abnormalities, fetal malformations, infections, hypertensive disorders, medical complications, and undetermined causes.
Results. 86% of stillbirths in this study had a probable cause of death. Umbilical and placental abnormalities were the most probable causes (62% and 41%, respectively). The two most common identified cord abnormalities were short cord length (34%) and marginal insertion (23%), while small placenta (27%) was the most common for placental abnormalities.
Conclusion. To be able to come up with the probable cause of stillbirth, the delivering physician or health personnel should always account the gross findings of the fetus and placenta after delivery.
Epidemiology of Injuries in the Philippines: An Analysis of Secondary Data
Authors: Rivera Adovich S. , Lam Hilton Y. , Macalino Joel U. 
Published: January 2021

Background. Injury surveillance is viewed as an important component of injury prevention. Several data systems in the Philippines exist but have not been analyzed together. Analyzing these readily available data can guide policy making.
Objective. This report aimed to describe the epidemiology of injuries in the Philippines using secondary datasets.
Method. Death data of 2013 from the Philippines Statistics Authority and injury surveillance data of 2014 from the Department of Health were obtained and recoded. Summary statistics were generated.
Results. Injured persons mainly come from the young age group. There were a higher number of males compared to females. Provincial variations in death rates for specific injury types existed. There did not seem to be an obvious pattern in injury occurrence according to month and time of day. High numbers of injuries were reported during daytime but admission and death rates peak at night. Injuries were shown to be an anatomically heterogeneous group with dominance in superficial injuries, head trauma, and hand fractures.
Conclusion. Analysis of secondary datasets revealed the epidemiology of injuries in the Philippines. Results have implications in health policy and injury prevention.