bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of SARS-CoV-2 pandemic on dermatology residents: A nationwide French study
Authors: Shourick Jason Philippe , Laurent Claire Simone-Marie , Mion Georges , Skayem Charbel Louis , Hamann Pierre Michel-Gilbert 
Published: October 2021

Background
Coronavirus disease 2019 (COVID-19) has changed the practice of all health-care professionals. Determining the impact could prevent repercussions in future crisis.

Objectives
The objectives of the study were to assess the impact of the COVID-19 pandemic on dermatology residents’ professional practice, working conditions, academic training and mental health.

Methods
An online questionnaire was sent to all French dermatology residents. We compared the activity of residents working in areas heavily impacted by COVID-19 to others. Logistic multivariate regressions were done, using as outcome variables the negative impact of the COVID crisis on residents’ possibility to practice dermatology during the crisis, supervision, academic training and working more than 50 h/week. The last part of the questionnaire was the burnout questionnaire of Maslach.

Results
A total of 246 residents filled the questionnaire. Residents working in highly impacted COVID areas (odds ratio, OR 0.34 confidence interval, CI [0.18, 0.61], P ≤ 0.001), first-year postgraduate (PGY-1) residents (OR 0.46 CI [0.23, 0.91], P = 0.023) and those in private practice (OR 0.10 CI [0.01, 0.57], P = 0.032) were significantly less able to maintain dermatology activities. Worse supervision was significantly more frequent with non-PGY-1 residents (OR 3.24 CI [1.65, 6.65], P < 0.001). One hundred and eighty one residents claimed the pandemic to have a negative effect on their dermatology curriculum with no difference according to their regions’ affection by COVID-19. This was mostly attributed to the cancelation of courses and congresses. PGY-1 residents (OR 2.09 CI [1.09, 4.04], P = 0.029) and residents in highly affected areas (OR 1.79 CI [1.01, 3.18], P = 0.049) were more at risk of working above the maximal legal working time. None of the residents was free of burnout symptoms.

Conclusion
Dermatology residents have been highly affected by COVID-19. It might be important to have a more integrated healthcare system to fight times of crisis with the least repercussions on residents.
Effectiveness and safety of 0.5% timolol solution in the treatment of pyogenic granuloma: A randomized, double-blind and placebo-controlled study
Authors: Patra Aparesh Chandra , Sil Amrita , Ahmed Sk. Shahriar , Rahaman Sufiur , Mondal Nasiruddin , Roy Sudipta , Datta Adrija , Kaliyadan Feroze , Panda Saumya , Setia Maninder Singh , Dogra Sunil , Khandpur Sujay , Hazra Avijit , Das Nilay Kanti 
Published: October 2021

Introduction
Pyogenic granulomas are benign vascular lesions of the skin and mucosa which are often a source of concern because of their recurrent bleeding even with minimal trauma. Current treatment for pyogenic granuloma is ablative; no medical therapy is standardized to date. Timolol, due to its vasoconstrictive effect, vascular growth factor inhibition and apoptosis promotion properties, is a potential therapeutic option. Objectives: To assess the effectiveness and safety of topical timolol in the treatment of pyogenic granulomas.

Methods
A two-centre, double-blind and placebo-controlled trial (Registration CTRI/2019/04/018581) was conducted. Patients of either sex were recruited with pyogenic granuloma lesions of less than eight weeks duration. Topical treatment with 0.5% timolol or matching glycerin placebo was continued for six weeks. Changes in color, size, bleeding tendency, physicians’ and patients’ global assessments and adverse events were assessed.

Results
Forty subjects were randomized between the two groups which were comparable in age, sex, duration of illness and baseline lesion size.Significant improvement was noted with timolol, with color change from first follow-up onwards and lesion size reduction from second follow-up onward. Patients’ assessment of bleeding tendency also showed imrovement from the second visit onward. Between-group comparison showed significant difference with respect to percentage reduction in size (timolol 40.9%, placebo 3.4%; P = 0.002). Rescue treatment (electrosurgery) was required in five patients on placebo and in one in the timolol group (P = 0.182). Complete resolution occurred in 2 (10%) patients with timolol and in no patients on placebo (P = 0.231). Limitations: We observed effects of treatment for only six weeks.

Conclusion
Topical timolol may be a treatment option for early pyogenic granulomas but complete resolution is unlikely in six weeks. Studies of longer duration are required to assess resolution and recurrence rates.
Efficacy of hemoporfin photodynamic therapy for pulsed dye laser-resistant facial port-wine stains in 107 children: A retrospective study
Authors: Zhang Li-Chao , Yang Jun , Huang Yuan-Bo , Bi Ming-Ye 
Published: October 2021

Background:
Port-wine stains occur in 0.3–0.5% newborns, mainly on the face and neck. Pulsed dye laser is recognized as the gold standard treatment; nevertheless, it is associated with a low cure rate and a high recurrence rate.

Aims:
This study aims to evaluate the efficacy of hemoporfin photodynamic therapy for pulsed dye laser-resistant port-wine stains in children.

Methods:
We studied 107 children who received hemoporfin photodynamic therapy for port-wine stains on the face and neck that were resistant to pulsed dye laser. After intravenous injection of 5 mg/kg hemoporfin, the local lesion was irradiated with 532 nm LED green light for 20 min with a power density of 80–100 mW/cm2. A total of 65 patients were given a second treatment after eight weeks. The efficacy and therapeutic responses were recorded at four days and eight weeks after each treatment.

Results:
The efficacy was positively correlated with the number of treatments received; two treatment sessions yielded significantly better results compared to a single treatment with a response rate of 96.9%, a significant response rate of 50.8% and a cure rate of 21.5%, respectively (P < 0.001). After two treatment sessions, the efficacy was negatively correlated with age (P = 0.04). The efficacy for port-wine stains located on the lateral part was better than that of the central face (P = 0.04). The efficacy for the pink type was better than that for the red and purple types (P = 0.03). No allergic or systematic adverse reactions were reported.

Limitations:
No objective measurement data were available.

Conclusion:
Hemoporfin photodynamic therapy is effective and safe for pulsed dye laser-resistant facial port-wine stains in children.
Pengaruh Biaya Produksi dan Biaya Promosi Terhadap Laba Bersih (Studi Pada Perusahaan Roti PT. Nippon Indosari Corpindo Tbk Yang Terdaftar Di Bursa Efek Indonesia Periode 2014-2019)
Authors: Antono Yulianus Viki , Suhendri Hendrik , Putri Sri Andika 
Published: October 2021

<div class="page" title="Page 1"><div class="layoutArea"><div class="column"><p><span>The purpose of this research is to find out the influence of production costs and promotional costs on net income at PT NIC Tbk which has been listed on the IDX for the 2014-2019 period. Meanwhile, in this research, quantitative methods are used and multiple linear regression analysis is used. The results found in this research are that the production cost variable can have a significant effect on net income, which can be proven through the value of t count = 7.299 (greater than t table = 2.447) and significant value = 0.000 (smaller than t table = 2.447) 0.05), so that hypothesis 1 can be accepted, while the promotion cost variable can also have a significant effect on net income, it can be proven through the t count = 5.881 (greater than t table = 2.447) and the significant value = 0.000 (less than 0.05), so hypothesis 2 can be accepted. The variable influence of production costs and promotion costs has a significant influence on the net profit of PT NIC Tbk which has been listed on the IDX for the 2014-2019 period of 20.8%. </span></p><p> </p></div></div></div>
Deteção de linguagem tendenciosa em decisões judiciais
Authors: Pinto Alexandra Guedes , Warrot Catarina Vaz , Cardoso Henrique Lopes , Duarte Isabel Margarida , Sousa-Silva Rui 
Published: October 2021

The linguistic expression of subjectivity is a complex phenomenon that has been the object of reflection by several sub-areas of Linguistics and, more recently, of Computational Linguistics. Linguistic subjectivity, in terms of the linguistic expression of the speaker's opinions and attitudes, affects all levels of discourse organization and is present, to different degrees, in diverse textual genres. Subjectivity and bias are connected, in the sense that the presence of bias in discourse has been related, both in Linguistics and Computational Linguistics, to the occurrence of signs of subjectivity.
Court decisions are an argumentative text genre that may convey traces of subjectivity but should not be biased. As a discourse that represents the State’s position on social matters, it should reflect the principle of Equality. Nonetheless, a preliminary analysis of cases of gender violence reveals that this is not always the case. The research proposed in this paper aims to study the linguistic formulations that convey subjectivity and bias in court decisions on gender violence against women. The goal is to develop a linguistic model to detect these instances of bias, with a future possibility of application in a tool for automatic detection of gender bias in discourse, fueled by Artificial Intelligence (AI) and Natural Language Processing (NLP) techniques. A corpus of court decisions on gender violence has been extracted from the public access database of Instituto de Gestão Financeira e Equipamentos da Justiça (IGFEJ), and has been subject to analysis. A set of examples has been compiled in the analytical section of this study, demonstrating the possibility of connecting certain linguistic features, such as mitigation and intensification mechanisms, evidential expressions and counter-argumentative movements, to the presence of subjectivity and bias in discourse.
Demarcation of the public and private in the interaction of the state and citizens on digital network platforms
Authors: Zotov V. V. 
Published: October 2021

Digital network platforms are built on sociotechnical interaction between actors and actors. The creation and development of new public services based on digital platforms inevitably leads to the transformation of the relationship between the state and citizens. The attractiveness of state digital platforms for citizens increases when resolving the contradiction between the possibilities of new forms of social interaction and the threat of misuse of personal data, the risk of harm or persecution.The article presents the results of the analysis of the boundaries of the public and private in the interaction of the state with citizens on digital network platforms. The research method is a comparative analysis, which is based on the dichotomy of public and private, reflected in the concept of private and public X. Arendt, concepts of the public sphere J. Habermas, regulatory and legal concepts of privacy by R. Gavison. The empirical base was made up of a sociological study conducted to obtain information about the boundaries of privacy and publicity of personal data in the digital network space (n = 1 000 among the population over 18 years old living in metropolitan megacities and median regions by the level of informatization, 2020) and the results of Kaspersky Lab surveys conducted in 2019–2020.The conducted research allows us to assert that almost 2/3 of citizens have faced the misuse of confidential information on the Internet. Most of the respondents are aware that websites, social networks and search engines can collect data for web analytics. At the same time, citizens consider it possible to transfer personal data to the authorities in a generalized form for making managerial decisions. Half of the surveyed population does not object to the implementation of digital control over the actions and movements of citizens. Thus, despite the existing negative experience, it is unlikely that there will be any obvious resistance to organizing the collection of personal information on digital network platforms.
الوعي الاستراتيجي ودوره في تحقيق متطلبات التجديد الاستراتيجي
Authors: Yousif Mehvan , Taher Mahabad 
Published: October 2021

تهدف هذه الدراسة إلى تحديد الوعي الاستراتيجي ودوره في تحقيق متطلبات التجديد الاستراتيجي، وتم تحديد الجامعات الخاصة في إقليم كوردستان ميداناً لإجراء الجانب العملي، وأعتمدت الدراسة على المنهج الوصفي التحليلي، وتم اعتماد على مجموعة من الفرضيات الرئيسية والفرعية التي أختبرت ميدانياً على عينة من الجامعات الخاصة والبالغ عددها (5) جامعات، ووُضعت عدد من الأسئلة الأساسية أجاب عنها (102) قائداً اكاديمياً، ولأغراض جمع البيانات تم الاعتماد على استمارة الاستبانة التي صممت لهذا الغرض، وجرى تحليل البيانات بإعتماد مجموعة من أساليب الإحصائية في برنامج (SPSS) لتحليل علاقة الارتباط والتأثير بين متغيرات الدراسة. وقد توصلت الدراسة إلى مجموعة من الاستنتاجات أهمها وجود علاقة ارتباط معنوية بين الوعي الاستراتيجي والتجديد الاستراتيجي، وكذلك وجود تأثير معنوي للوعي الاستراتيجي في التجديد الاستراتيجي، وتضمنت الدراسة عدداً من المقترحات للجامعات المبحوثة لتعزيز أبعاد الوعي الاستراتيجي عند القيادات الاكاديمية فيها، وكيفية الوصول إلى تحقيق متطلبات التجديد الاستراتيجي، فضلاً عن اقتراح مجموعة من الدراسات المستقبلية لباحثين آخرين في هذا المجال.
COVID-19 Menace: Stepwise Measures with Respect to Diet
Authors: Monali G Kurhadkar  , Renu Rathi  , Bharat Rathi  , Sandesh Khobragade  
Published: October 2021

Human being all over the world is suffering due to the recent outbreaks of COVID-19 and prevention of viral infections emerges as a critical issue in safeguarding public health. According to Ayurveda, COVID-19 is considered as an Agantuja Jwar in which Agantu (outside) agent attacking the body. It is Sansargajanya (Aupasargika Roga) causing epidemic or pandemic infection. As no treatment is found effective, diet plays an important role to improve immunity towards viral diseases. Relevant references were searched related to diet described in Ayurveda treaties. Scientific research papers related to clinical studies on dietetic drugs were also searched. The concept of balanced diet for healthy living has been explained by various Acharyas of Ayurveda, Acharya Kashyapa mentioned that the stability of an individual health is dependent on Ahara and there is nothing best except diet for sustaining the life of human beings. He has also equated Ahara as Bheshaja (medicine) and nothing else is considered as Mahabheshaja (Superior Medicine). Here treatment is suggested as per symptoms available through patients and as per Ayurveda, dietary habits followed during COVID-19 and boosting immunity to fights against pandemic diseases through yoga and Rasayana Chikitsa.
Strategi Implementasi Adaptive Neuro Fuzzy Inference System (ANFIS) pada Kendali Motor Induksi 3 Fase Metode Vektor-Tidak Langsung
Authors: FAKHRUDDIN HANIF HASYIER , TOAR HANDRI , PURWANTO ERA , OKTAVIANTO HARY , BASUKI GAMAR , APRIYANTO RADEN AKBAR NUR , MUNTASHIR ABDILLAH AZIZ 
Published: October 2021

ABSTRAKKendali vektor merupakan solusi terbaik dalam kendali motor induksi untuk meningkatkan karakter dinamis dan efisiensinya. Pada penelitian ini, sebuah kendali kecepatan PID dipadukan dengan Adaptive Neuro Fuzzy Inference System (ANFIS) untuk meningkatkan keandalan pada berbagai kecepatan acuan. Metode cerdas Particle Swarm Optimization (PSO) digunakan untuk optimasi dataset ANFIS. Pengujian keandalan dilakukan dengan membandingkan PID konvensional dengan PID-ANFIS pada motor induksi 3 fase berdaya 2HP. Validasi penelitian dilakukan melalui simulasi di platform LabView. PID-ANFIS membuktikan hasil yang jauh lebih baik dari kendali PID konvensional pada berbagai kecepatan acuan. Pemilihan rise time tercepat sebagai fungsi fitness menghasilkan kendali yang memiliki dead time dan rise time 1.5x lebih cepat. PID-ANFIS berhasil menghilangkan undershoot dan osilasi steady state ketika uji kecepatan tinggi.Kata kunci: Kendali Vektor, Adaptive Neuro Fuzzy Inference System, Particle Swarm Optimization, LabView ABSTRACTVector control is the best solution in induction motor control to enhance its dynamic character and efficiency. In this research, a PID speed controller is combined with the Adaptive Neuro-Fuzzy Inference System (ANFIS) to enhance reliability at various reference speeds. The intelligent method Particle Swarm Optimization (PSO) is used to optimize the ANFIS dataset. Reliability testing is done by comparing conventional PID with PID-ANFIS on a 2HP 3-phase induction motor. The research validation was carried out through a simulation on the LabView platform. The PID-ANFIS proved significantly better results than conventional PID control at a wide range of reference speeds. Selection of the fastest rise time as a fitness function results in a control that has a dead time and a rise time of 1.5x faster. PID-ANFIS successfully negates undershoot and steadystate oscillations during high-speed tests.Keywords: Vector Control, Adaptive Neuro Fuzzy Inference System, Particle Swarm Optimization, LabView
Kebersyukuran dan Kesejahteraan Subjektif pada Guru SMA Negeri I Sewon
Authors: Suseno Miftahun Ni'mah , Pramithasari Adina 
Published: October 2021

Kesejahteraan subjektif merupakan kebahagiaan yang diperoleh individu dari evaluasi kognitif dan afektif individu dalam kehidupannya. Penelitian ini melihat hubungan antara bersyukur dengan subjective well being. Sampel adalah 51 orang guru SMA Sewon Bantul. Pengumpulan data mengumpulkan skala subjective well being dan kemudian dianalsis menggunakan Pearson Product Moment. Hasil penelitian menunjukkan bahwa ada korelasi positif ant ara bersyukur dengan Subjective Well Being. Bersyukur juga berkontribusi secara efektif terhadap Subjective Well Being.
Regulasi Emosi Remaja dari Ibu Pekerja Migran dan Non Migran
Authors: Intan Ayu Lasmana Firdauza  , Farah Farida Tantiani  
Published: October 2021

Regulasi emosi merupakan kemampuan individu dalam mengelola atau mengontrol emosi. Banyak remaja yang tidak dapat mengelola emosi mereka secara efektif sehingga rentan terhadap depresi. Penelitian ini bertujuan untuk membandingkan regulasi emosi cognitive reappraisal dan expressive suppression pada remaja. Menggunakan metode kuantitatif komparatif, penelitian ini melibatkan 101 responden yang dipilih melalui purposive technique sampling. Pengumpulan data menggunakan skala ERQ (Emotion Regulation Questionnaire) yang terdiri dari 10 pertanyaan dan selanjutnya dianalisis dengan independent sample t-test. Hasil penelitian menunjukkan bahwa ada perbedaan yang signifikan pada expressive suppression namun tidak ada perbedaan pada cognitive reappraisal. Implikasi penelitian ini menunjukkan pentingnya para ibu yang menjadi pekerja migran untuk tetap menjaga interaksi dengan anaknya. Faktor kualitas dan kuantitas interaksi antara ibu dan anak dapat menjadi bahan penelitian selanjutnya.
Kepuasan Pasien Ditinjau dari Komunikasi Perawat-Pasien
Authors: Khairani Maya , Salviana Desi , Abu Bakar  
Published: October 2021

Kepuasan pasien sebagai salah satu aspek penting dalam pelayanan kesehatan seringkali dilihat dari berbagai aspek. Penelitian ini bertujuan untuk mengetahui hubungan antara komunikasi perawat dengan kepuasan pasien. Sejumlah 95 pasien rawat inap di Rumah Sakit X menjadi responden dalam penelitian ini. Data dikumpulkan melalui Skala Komunikasi Perawat-Pasien dan Skala Kepuasan Pasien. Hasil analisis data dengan menggunakan korelasi pearson menunjukkan bahwa terdapat hubungan yang positif dan signifikan antara komunikasi perawat-pasien dengan kepuasan pasien. Dengan kata lain komunikasi efektif yang dilakukan oleh perawat terhadap pasien akan meningkatkan kepuasan para pasien. Penelitian ini berimplikasi pada budaya organisasi rumah sakit yang mengedepankan komunikasi efektif baik antar sesama tenaga kesehatan maupun dengan para pasien.
Segment tip geometry of sheet intrusions, I: Theory and numerical models for the role of tip shape in controlling propagation pathways
Authors: Walker Richard , Stephens Tara , Greenfield Catherine , Gill Simon , Healy Dave , Poppe Sam 
Published: October 2021

Inferences about sheet intrusion emplacement mechanisms have been built largely on field observations of intrusion tip zones: magmatic systems that did not grow beyond their observed state. Here we use finite element simulation of elliptical to superelliptical crack tips, representing observed natural sill segments, to show the effect of sill tip shape in controlling local stress concentrations, and the potential propagation pathways. Stress concentration magnitude and distribution is strongly affected by the position and magnitude of maximum tip curvature κmax. Elliptical tips concentrate stress in-plane with the sill, promoting coplanar growth. Superelliptical tips concentrate maximum tensile stress (σmax) and shear stress out-of-plane of the sill, which may promote non-coplanar growth, vertical thickening, or coplanar viscous indentation. We find that σmax = Pe(1+ 2(√[aκmax]), where Pe is magma excess pressure and a is sill half length. At short length-scales, blunted tips locally generate large tensile stresses; at longer length-scales, elliptical-tipped sills become more efficient at concentrating stress than blunt sills.
Process Validation in Pharmaceutical Product Development: An Overview
Authors: M Sreenivasa.G. , T Sriranga. , Banakar Naveen , Kori Vaishakha , Vasanad Chetankumar , P Pavankumar.S. 
Published: October 2021

As per GMP process validation is very important and required part in product development. Process Validation is required for ensuring and providing the documentary evidence and also required for giving the Surety that process by which the formulation is prepared is capable of consistently producing the product of required quality and purity.
A validated manufacturing process is one which has been proved to do what it purports on is represented to do. The proof of validation is obtained through the collection and evaluation of data, preferably, beginning from the process development phase and Continuing through the production phase. Validation necessarily includes process qualification (the qualification of materials, equipment Systems, buildings, personnel), but it also includes the control on the entire process for repeated batches or runs. This article gives a general introduction and overview about process validation in pharmaceutical manufacturing process and its importance.
Keywords: GMP, Validation, validation manufacturing process.