bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plant Hormone Metabolome and Transcriptome Analysis of Dwarf and Wild-type Banana
Authors: Deng Biao , Wang Xuan , Long Xing , Fang Ren , Zhou Shuangyun , Zhang Ji , Peng Xiaolu , An Zhenyu , Huang Weixiong , Tang Wenzhong , Gao Yining , Yao Jinyan 
Published: July 2021

AbstractGibberellin (GA), auxin (IAA) and brassinosteroid (BR) are indispensable in the process of plant growth and development. Currently, research on the regulatory mechanism of phytohormones in banana dwarfism is mainly focused on GA, and few studies are focused on IAA and BR. In this study, we measured the contents of endogenous GA, IAA and BR and compared the transcriptomes of wild-type Williams banana and its dwarf mutant across five successive growth periods. We investigated the relationship between hormones and banana dwarfism and explored differential gene expression through transcriptome analysis, thus revealing the possible metabolic regulatory mechanism. We inferred a complex regulatory network of banana dwarfing. In terms of endogenous hormone levels, GA and IAA had significant effects on banana dwarfing, while BR had little effect. The key gene in GA biosynthesis of is GA2ox, and the key genes in IAA biosynthesis are TDC and YUCCA. The differential expression of these genes might be the main factor affecting hormone levels and plant height. In terms of hormone signal transduction, DELLA and AUX/IAA repressor proteins were the core regulators of GA and IAA, respectively. They inhibited the process of signal transduction and had feedback regulation on hormone levels. Finally, the transporter protein PIN, AUX1/LAX protein family and ABCB subfamily played supplementary roles in the transport of IAA. These results provide new insights into GA and IAA regulation of banana growth and a reliable foundation for the improvement of dwarf varieties.
Complications and mortality after catheter ablation of ventricular arrhythmias: risk in VT ablation (RIVA) score
Authors: Mathew Shibu , Fink Thomas , Feickert Sebastian , Inaba Osamu , Hashiguchi Naotaka , Schlüter Michael , Wohlmuth Peter , Wissner Erik , Tilz Roland Richard , Heeger Christian-Hendrik , Rottner Laura , Reissmann Bruno , Rillig Andreas , Metzner Andreas , Maurer Tilman , Kuck Karl-Heinz , Ouyang Feifan 
Published: July 2021

Abstract
Aims
Catheter ablation of ventricular arrhythmias (VA) has proven to be an effective therapeutic option for secondary arrhythmia prophylaxis. We sought to assess the procedural efficacy, safety and in-hospital mortality of a large patient cohort with and without structural heart disease undergoing VA ablation.

Methods
A total of 1417 patients (804 patients with structural heart disease) undergoing 1792 endo- and epicardial procedures were analyzed. Multivariable risk factor analysis for occurrence of major complications and intrahospital mortality was obtained and a score to allow preprocedural risk assessment for patients undergoing VA ablation procedures was established.

Results
Major complication occurred in 4.4% of all procedures and significantly more often in patients with structural heart disease than in structurally normal hearts (6.0 vs. 1.8%). The frequency of these periprocedural complications was significantly different between procedures with sole right ventricular and a combination of RV and LV access (0.5 vs. 3.1%). The most common complication was cardiac tamponade in 46 cases (3.0%). Intrahospital death was observed in 32 patients (1.8%). Logistic regression model revealed presence of ischemic heart disease, epicardial ablation, presence of oral anticoagulation or dual antiplatelet therapy as independent risk factors for the occurrence of complications or intrahospital death, while a history of previous heart surgery was an independent predictor with a decreased risk. Based on this analysis a risk score incorporating 5 standard variables was established to predict the occurrence of complications and intrahospital mortality.

Conclusions
Safety of VA catheter ablation mainly relies on patient baseline characteristics and the type of access into the ventricles or epicardial space.
Seroprevalence of Toxoplasma gondii and associated risk factors in domestic pigs raised from Cuba
Authors: Castillo-Cuenca Julio César , Martínez-Moreno Álvaro , Diaz-Cao José Manuel , Entrena-García Angel , Fraga Jorge , Arias Pedro Casanova , Almería Sonia , García-Bocanegra Ignacio 
Published: July 2021

AbstractA cross-sectional study was carried out to determine the seroprevalence of Toxoplasma gondii and associated risk factors in pigs in the largest pork-producing region in Cuba. Serum samples from 420 pigs, including 210 sows and 210 post-weaning pigs, were tested for antibodies against T. gondii using a commercial indirect enzyme-linked immunosorbent assay. Anti-T. gondii antibodies were detected in 56 animals (13.3%, 95% CI: 10.1–16.6). A generalized estimating equations model revealed that the risk factors associated with higher seropositivity in pigs were altitude (higher in farm’s location < 250 m above sea level (masl) versus ≥ 250 masl) and age (higher in sows compared to post-weaning pigs). The results indicated that this protozoan parasite is widely distributed on pig farms in the study area, which is a public health concern since the consumption of raw or undercooked pork meat products containing tissue cysts is considered one of the main routes of T. gondii transmission worldwide. Control measures should be implemented to reduce the risk of exposure to T. gondii in pigs in Cuba.
»Bemitleide dich mal nicht selbst!«
Authors: Sievers Luisa , Singer Susanne 
Published: July 2021

ZusammenfassungGewalterfahrungen in der Kindheit und Jugend werden möglicherweise psychisch so verarbeitet, dass das Gegenüber später in einer spezifischen Weise auf die Betroffenen reagiert. Wir untersuchten dies anhand der Frage, ob sich Reaktionen (Assoziationen) auf Berichte an den Gutachter dahingehend unterscheiden, ob der Patient Gewalterfahrungen in der Kindheit oder Jugend in der Herkunftsfamilie gemacht hat oder nicht. Es wurden 22 pseudonymisierte Berichte an den Gutachter im Rahmen des Antragsverfahrens auf Kostenübernahme von Psychotherapie von zwei Untersucherinnen qualitativ analysiert. Die Analyse erfolgte über die Qualitative Inhaltsanalyse nach Mühlfeld.Beim Vergleich der deduktiv entwickelten Kategoriensysteme konnten im Hinblick auf die Reaktionsmuster Parallelen, aber auch mehrere Differenzen zwischen den beiden Patientengruppen festgestellt werden. Als Reaktionsmuster auf Patienten mit Gewalterfahrung zeigten sich Sprachlosigkeit, Tod oder Sich-verstecken-Wollen, was sich so bei der anderen Gruppe nicht fand. Parallelen ergaben sich unter anderem bei Reaktionsmustern von Zartheit, Ekel oder Relativierung von Leid. Bei Berichten über Patienten ohne Gewalterfahrung kam es zu einer größeren emotionalen Varianz in den Reaktionsmustern.Die gefundenen Reaktionsmuster stimmen nur teilweise mit Angaben der Literatur zu „typischen“ Gegenübertragungsreaktionen auf traumatisierte Patienten überein. Die geringere emotionale Varianz gegenüber Berichten von Patienten mit Gewalterfahrungen könnte ein empirischer Beleg für deren geringere Symbolisierungsfähigkeiten sein.
Methodik zur Bestimmung von optimalen Messpunkten bei der strukturdynamischen Vermessung elektrischer Maschinen
Authors: Franck Marius , Mönninghoff Sebastian , Butterweck Daniel , Hameyer Kay 
Published: July 2021

ZusammenfassungExperimentelle Modalanalysen von Komponenten und Baugruppen elektrischer Maschinen, die eine Modellkorrelation erlauben, sind sehr zeitaufwändig. Eine gezielte Planung ist deshalb essenziell. Die Platzierung von Mess- und Anregungspunkten kann einen signifikanten Einfluss auf die Güte der Messergebnisse und der extrahierten Parameter haben. In dieser Arbeit werden Verfahren zur modellbasierten Messpunktidentifikation analysiert und weiterentwickelt. Mit dem weiterentwickelten Verfahren ist es erstmals möglich für gesamte Baugruppen von elektrischen Maschinen potenzielle Messpunkte automatisiert zu identifizieren. Es werden Ergebnisse mit ersten Messungen abgeglichen und analysiert.
Physician–patient communication affects patient satisfaction in treatment decision-making: a structural equation modelling analysis of a web-based survey in patients with ulcerative colitis
Authors: Matsuoka Katsuyoshi , Ishikawa Hirono , Nakayama Takeo , Honzawa Yusuke , Maemoto Atsuo , Hirai Fumihito , Ueno Fumiaki , Sato Noriko , Susuta Yutaka , Hibi Toshifumi 
Published: July 2021

Abstract
Background
The relationship of bidirectional sharing of information between physicians and patients to patient satisfaction with treatment decision-making for ulcerative colitis (UC) has not been examined. Here, we conducted a web-based survey to evaluate this relationship.

Methods
Patients aged ≥ 20 years with UC were recruited from the IBD Patient Panel and Japanese IBD Patient Association. Patients completed our web-based survey between 11 May and 1 June 2020. The main outcomes were patient satisfaction (assessed by the Decision Regret Scale) and patient trust in physicians (assessed by the Trust in Physician Scale).

Results
In this study (n = 457), a structural equation modelling analysis showed that physician-to-patient and patient-to-physician information significantly affected patient satisfaction with treatment decision-making (standardised path coefficient: 0.426 and 0.135, respectively) and patient trust in physicians (0.587 and 0.158, respectively). Notably, physician-to-patient information had a greater impact. For patient satisfaction with treatment decision-making and patient trust in physicians, information on “disease” (indirect effect: 0.342 and 0.471, respectively), “treatment” (0.335 and 0.461, respectively), and “endoscopy” (0.295 and 0.407, respectively) was particularly important, and the level of this information was adequate or almost adequate. Patient-to-physician information on “anxiety and distress” (0.116 and 0.136, respectively), “intention and desire for treatment” (0.113 and 0.132, respectively), and “future expectations of life” (0.104 and 0.121, respectively) were also important for patient satisfaction with treatment decision-making and patient trust in physicians, but these concerns were not adequately communicated.

Conclusions
Adequate physician–patient communication, especially physician-to-patient information, enhanced patient satisfaction with treatment decision-making for UC.
Observations on soil-atmosphere interactions after long-term monitoring at two sample sites subjected to shallow landslides
Authors: Bordoni M. , Bittelli M. , Valentino R. , Vivaldi V. , Meisina C. 
Published: July 2021

AbstractSoil-atmosphere interaction has implications in different scientific research contexts and is increasingly investigated through field measurements. This paper reports a detailed description of interaction between shallow soil and atmosphere at two test sites in Oltrepò Pavese area (Northern Italy). The two test sites are in the same climatic area but are characterised by different geological features. In fact, the first objective is to compare the behaviour of two different soils, namely a clayey-sandy silt (CL) and a silty clay (CH), under similar meteorological events. Soil-atmosphere interaction is studied on the basis of long-term (about 87 and 42 months for the two test sites, respectively) monitoring data of both volumetric water content and soil water potential, recorded at different depths along two vertical soil profiles in the first two metres from ground level. Field measurements, together with meteorological data such as precipitation and air temperature, allow for clear identification of the seasonal fluctuations of unsaturated soil hydraulic properties. To infer detailed information, the recorded data were processed and relationships between soil water potential and water content were investigated. Different time spans, from several months to a few days, even including single rainy events, are considered to show the hydraulic soil behaviour. The hysteretic cycles of water content with respect to soil water potential and non-equilibrium flow are highlighted. In particular, the measured soil water potential is in the range of 0–800 kPa and of 0–1500 kPa for the CL and CH soil, respectively. At both sites, the observed hysteretic cycles are more frequent in the hot season (summer) than in the cold season (winter) and tend to reduce with depth. The experimental results are compared with the soil water characteristic curves (SWCCs) to assess whether and to what extent the SWCCs are reliable in modelling the hydraulic behaviour of partially saturated soils, under atmospheric forcing, at least in the considered climatic contexts.
Impact of sarcopenia in advanced and metastatic soft tissue sarcoma
Authors: Strassmann Dennis , Hensen Bennet , Grünwald Viktor , Stange Katharina , Eggers Hendrik , Länger Florian , Omar Mohamed , Zardo Patrick , Christiansen Hans , Reuter Christoph W. , Wacker Frank K. , Ganser Arnold , Ivanyi Philipp 
Published: July 2021

Abstract
Introduction
Advanced or metastatic soft tissue sarcoma (a/mSTS) is associated with a dismal prognosis. Patient counseling on treatment aggressiveness is pivotal to avoid over- or undertreatment. Recently, evaluation of body composition markers like the skeletal muscle index (SMI) became focus of interest in a variety of cancers. This study focuses on the prognostic impact of SMI in a/mSTS, retrospectively.

Methods
181 a/mSTS patients were identified, 89 were eligible due to prespecified criteria for SMI assessment. Baseline CT-Scans were analyzed using an institutional software solution. Sarcopenia defining cut-off values for the SMI were established by optimal fitting method. Primary end point was overall survival (OS) and secondary endpoints were progression free survival (PFS), disease control rate (DCR), overall response rate (ORR). Descriptive statistics as well as Kaplan Meier- and Cox regression analyses were administered.

Results
28/89 a/mSTS patients showed sarcopenia. Sarcopenic patients were significantly older, generally tended to receive less multimodal therapies (62 vs. 57 years, P = 0.025; respectively median 2.5 vs. 4, P = 0.132) and showed a significantly lower median OS (4 months [95%CI 1.9–6.0] vs. 16 months [95%CI 8.8–23.2], Log-rank P = 0.002). Sarcopenia was identified as independent prognostic parameter of impaired OS (HR 2.40 [95%-CI 1.4–4.0], P < 0.001). Moreover, DCR of first palliative medical treatment was superior in non-sarcopenic patients (49.2% vs. 25%, P = 0.032).

Conclusion
This study identifies sarcopenia as a prognostic parameter in a/mSTS. Further on, the data suggest that sarcopenia shows a trend of being associated with first line therapy response. SMI is a promising prognostic parameter, which needs further validation.
A note on symmetry breaking in a non linear marketing model
Authors: Caravaggio Andrea , Cerboni Baiardi Lorenzo , Sodini Mauro 
Published: July 2021

AbstractIn this paper, we consider the nonlinear discrete-time dynamic model proposed by Bischi and Baiardi (Chaos Solitons Fractals 79:145-156, 2015a). The model considers players with adaptive adjustment mechanisms towards the best reply and a form of inertia in adopting such mechanism. Moreover, we formulate an extension of the original model, where endogenous market size is considered. Through numerical simulations, we show that multiple attractors may exist in the presence of homogeneous agents and the emergence of non-synchronized trajectories both in the short (on-off intermittency) and long (global riddling) run. Therefore, the article highlights that strategic contexts exist in which the players’ knowledge of the market and the adoption of the best reply do not always allow the use of the representative agent’s rhetoric to describe the dynamics of the model.
On the money creation approach to banking
Authors: Faure Salomon , Gersbach Hans 
Published: July 2021

AbstractWe study today’s two-tier money creation and destruction system: Commercial banks create bank deposits (privately created money) through loans to firms or asset purchases from the private sector. Bank deposits are destroyed when households buy bank equity or when firms repay loans. Central banks create electronic central bank money (publicly created money or reserves) through loans to commercial banks. In a simple general equilibrium setting, we show that symmetric equilibria yield the first-best level of money creation and lending when prices are flexible, regardless of monetary policy and capital regulation. When prices are rigid, we identify the circumstances in which money creation is excessive or breaks down and the ones in which an adequate combination of monetary policy and capital regulation can restore efficiency. Finally, we provide a series of extensions and generalizations of the results.
Osteoprotegerin and RANKL-RANK-OPG-TRAIL signalling axis in heart failure and other cardiovascular diseases
Authors: Dutka Mieczysław , Bobiński Rafał , Wojakowski Wojciech , Francuz Tomasz , Pająk Celina , Zimmer Karolina 
Published: July 2021

AbstractOsteoprotegerin (OPG) is a glycoprotein involved in the regulation of bone remodelling. OPG regulates osteoclast activity by blocking the interaction between the receptor activator of nuclear factor kappa B (RANK) and its ligand (RANKL). More and more studies confirm the relationship between OPG and cardiovascular diseases. Numerous studies have confirmed that a high plasma concentration of OPG and a low concentration of tumour necrosis factor–related apoptosis inducing ligand (TRAIL) together with a high OPG/TRAIL ratio are predictors of poor prognosis in patients with myocardial infarction. A high plasma OPG concentration and a high ratio of OPG/TRAIL in the acute myocardial infarction are a prognostic indicator of adverse left ventricular remodelling and of the development of heart failure. Ever more data indicates the participation of OPG in the regulation of the function of vascular endothelial cells and the initiation of the atherosclerotic process in the arteries. Additionally, it has been shown that TRAIL has a protective effect on blood vessels and exerts an anti-atherosclerotic effect. The mechanisms of action of both OPG and TRAIL within the cells of the vascular wall are complex and remain largely unclear. However, these mechanisms of action as well as their interaction in the local vascular environment are of great interest to researchers. This article presents the current state of knowledge on the mechanisms of action of OPG and TRAIL in the circulatory system and their role in cardiovascular diseases. Understanding these mechanisms may allow their use as a therapeutic target in cardiovascular diseases in the future.
A First-Principle Study of Monolayer Transition Metal Carbon Trichalcogenides
Authors: Khan Muhammad Yar , Liu Yan , Wang Tao , Long Hu , Chen Miaogen , Gao Dawei 
Published: July 2021

AbstractMonolayer MnCX3 metal–carbon trichalcogenides have been investigated by using the first-principle calculations. The compounds show half-metallic ferromagnetic characters. Our results reveal that their electronic and magnetic properties can be altered by applying uniaxial or biaxial strain. By tuning the strength of the external strain, the electronic bandgap and magnetic ordering of the compounds change and result in a phase transition from the half-metallic to the semiconducting phase. Furthermore, the vibrational and thermodynamic stability of the two-dimensional structure has been verified by calculating the phonon dispersion and molecular dynamics. Our study paves guidance for the potential applications of these two mono-layers in the future for spintronics and straintronics devices.
The effect of polyhedral oligomeric silsesquioxanes (POSSs) incorporation in ethylene-propylene-diene-terpolymer (EPDM): a thermal study
Authors: Blanco Ignazio , Zaharescu Traian 
Published: July 2021

AbstractA series of ethylene-propylene-diene-terpolymer (EPDM)/polyhedral oligomeric silsesquioxane (POSS) composites at different percentage of POSS were prepared and subjected to γ-irradiation. Both irradiated and non-irradiated EPDM and composites were investigated by the means of thermal analysis to verify if the presence of POSS molecules is able to reduce the oxidation level of free radicals generated during the degradation and to evaluate the effects of the irradiation. EPDM composites at 1, 3 and 5 mass% of POSS were thus degraded in a thermogravimetric (TG) balance in dynamic heating conditions (25–700 °C), in both inert and oxidative atmosphere by flowing nitrogen and air respectively. Thermal characterization was then completed by carrying out Differential Scanning Calorimetry (DSC) analysis from sub-ambient to better highlight the melting of the polymer and polymer composites occurring just above the room temperature. FTIR spectroscopy was also performed for the prepared samples to check the presence of the molecular filler in the composites and for the TG’s residue at 700 °C, in order to evaluate its nature. DSC and TGA parameters were detected and discussed to have information about the effect of the degradation’s environment, the effect of irradiation on polymer stabilization and the effect of POSS content in the polymer matrix.
Comparison of human blood serum DSC profiles in aqueous and PBS buffer solutions
Authors: Michnik Anna , Kiełboń Agnieszka , Duch Klaudia , Sadowska-Krępa Ewa , Pokora Ilona 
Published: July 2021

AbstractThe results of studies of physiological fluids by differential scanning calorimetry (DSC) for the purpose of diagnosis and monitoring of diseases are promising. Before the DSC method is accepted in medical diagnostics, it is worth experimenting with various environmental conditions at the research stage. Among other things, it is important to choose an appropriate solvent to dilute the tested biological fluids. In this work, human blood sera DSC profiles in aqueous and PBS (phosphate-buffered saline) solutions have been compared. Visibility of haptoglobin in the DSC profile of human blood serum is much better in water solution. In addition, contributions from albumin and haptoglobin are well separated in contrast to the PBS serum solutions. The peak or shoulder at about 83 °C which represents contributions from the CH3 domain of immunoglobulin IgG1 and/or transferrin is more clearly visible in PBS solution. The results show that the type of solvent is essential when interpreting the serum DSC profile.