bluuebunny/crossref_metadata_2025_split huggingface dataset:
All-metal wideband metasurface for near-field transformation of medium-to-high gain electromagnetic sources
Authors: Lalbakhsh Ali , Afzal Muhammad U. , Hayat Touseef , Esselle Karu P. , Mandal Kaushik 
Published: May 2021

AbstractElectromagnetic (EM) metasurfaces are essential in a wide range of EM engineering applications, from incorporated into antenna designs to separate devices like radome. Near-field manipulators are a class of metasurfaces engineered to tailor an EM source’s radiation patterns by manipulating its near-field components. They can be made of all-dielectric, hybrid, or all-metal materials; however, simultaneously delivering a set of desired specifications by an all-metal structure is more challenging due to limitations of a substrate-less configuration. The existing near-field phase manipulators have at least one of the following limitations; expensive dielectric-based prototyping, subject to ray tracing approximation and conditions, narrowband performance, costly manufacturing, and polarization dependence. In contrast, we propose an all-metal wideband phase correcting structure (AWPCS) with none of these limitations and is designed based on the relative phase error extracted by post-processing the actual near-field distributions of any EM sources. Hence, it is applicable to any antennas, including those that cannot be accurately analyzed with ray-tracing, particularly for near-field analysis. To experimentally verify the wideband performance of the AWPCS, a shortened horn antenna with a large apex angle and a non-uniform near-field phase distribution is used as an EM source for the AWPCS. The measured results verify a significant improvement in the antenna’s aperture phase distribution in a large frequency band of 25%.
Rbm24 displays dynamic functions required for myogenic differentiation during muscle regeneration
Authors: Grifone Raphaëlle , Saquet Audrey , Desgres Manon , Sangiorgi Claudia , Gargano Caterina , Li Zhenlin , Coletti Dario , Shi De-Li 
Published: May 2021

AbstractSkeletal muscle has a remarkable capacity of regeneration after injury, but the regulatory network underlying this repair process remains elusive. RNA-binding proteins play key roles in the post-transcriptional regulation of gene expression and the maintenance of tissue homeostasis and plasticity. Rbm24 regulates myogenic differentiation during early development, but its implication in adult muscle is poorly understood. Here we show that it exerts multiple functions in muscle regeneration. Consistent with its dynamic subcellular localization during embryonic muscle development, Rbm24 also displays cytoplasm to nucleus translocation during C2C12 myoblast differentiation. In adult mice, Rbm24 mRNA is enriched in slow-twitch muscles along with myogenin mRNA. The protein displays nuclear localization in both slow and fast myofibers. Upon injury, Rbm24 is rapidly upregulated in regenerating myofibers and accumulates in the myonucleus of nascent myofibers. Through satellite cell transplantation, we demonstrate that Rbm24 functions sequentially to regulate myogenic differentiation and muscle regeneration. It is required for myogenin expression at early stages of muscle injury and for muscle-specific pre-mRNA alternative splicing at late stages of regeneration. These results identify Rbm24 as a multifaceted regulator of myoblast differentiation. They provide insights into the molecular pathway orchestrating the expression of myogenic factors and muscle functional proteins during regeneration.
Elastocaloric-effect-induced adiabatic magnetization in paramagnetic salts due to the mutual interactions
Authors: Squillante Lucas , Mello Isys F. , Seridonio Antonio C. , de Souza Mariano 
Published: May 2021

AbstractThe temperature change under adiabatic stress, i.e., the elastocaloric effect, is a well-understood phenomenon and of particular interest due to its potential application in alternative ways for refrigeration. Here, we demonstrate that in the regime of low-temperatures (a few mK) real paramagnets can be magnetized when compressed adiabatically without applied magnetic field. Such adiabatic magnetization is a genuine many-body problem, stemming from the inherent dipolar mutual interactions between adjacent magnetic moments. We showcase experimental setups to carry out adiabatic magnetization and thus to access such a subtle effect. Perspectives of further investigations by controlling the mutual interactions in Bose–Einstein condensates in magnetic insulators and dipolar spin-ice systems via the adiabatic increase of temperature are also presented. Yet, we discuss the connection between the elastic Grüneisen parameter and the shift on the critical temperature of second-order phase transitions under adiabatic stress, as well as its connection with the Ehrenfest relation.
Prevalence and predictive factors of osteoporosis in Thai systemic sclerosis
Authors: Chuealee Wiriya , Foocharoen Chingching , Mahakkanukrauh Ajanee , Suwannaroj Siraphop , Pongchaiyakul Chatlert , Nanagara Ratanavadee 
Published: May 2021

AbstractSystemic sclerosis (SSc) is recognized as a chronic inflammatory disease and several SSc-associated factors may increase the risk of osteoporosis and its related fractures. To determine the prevalence and predictive factors of osteoporosis in Thai SSc, a cross-sectional study was designed in adult SSc patients at Scleroderma clinic, Khon Kaen University Hospital. The prevalence of osteoporosis with the 95% confidence interval (CI) were determined and the odds ratio (OR) with 95%CI were assessed the clinical association with osteoporosis. A total of 205 SSc patients were recruited with the female to male ratio of 2.7:1. The majority of cases were diffuse SSc subset (83.4%) with a disease duration < 5 years (62.9%). The overall prevalence of osteoporosis was 29.3% (95%CI 23.1–36.0). After an age adjusted analysis, the respective prevalence of osteoporosis at lumbar spine (LS) in women and men was 26.3% and 10%, while the prevalence of osteoporosis at the femoral neck (FN) in women and men was 11% and 2.1%. Low BMI (≤ 18.5 kg/m2) and menopause were associated with osteoporosis at both the LS and FN. Using multivariate analysis, low BMI and menopause were associated with osteoporosis at LS (OR 7.78 and 5.32, respectively), while low BMI was also associated with osteoporosis at LS in pre-menopausal women. In conclusion, the prevalence of osteoporosis in Thai SSc was 29.3%. Osteoporosis at the LS is more common than FN in both men and women. Low BMI was associated with osteoporosis in overall SSc and pre-menopausal women, while only menopause was associated with osteoporosis at the FN.
Mitigation of bacterial spot disease induced biotic stress in Capsicum annuum L. cultivars via antioxidant enzymes and isoforms
Authors: Ramzan Musarrat , Sana Sundas , Javaid Nida , Shah Anis Ali , Ejaz Samina , Malik Waqas Nazir , Yasin Nasim Ahmad , Alamri Saud , Siddiqui Manzer H. , Datta Rahul , Fahad Shah , Tahir Nazia , Mubeen Sidra , Ahmed Niaz , Ali Muhammad Arif , El Sabagh Ayman , Danish Subhan 
Published: May 2021

AbstractBacterial spot, caused by a group ofXanthomonads(Xanthomonasspp.), is a devastating disease. It can adversely affect theCapsicum annumproductivity. Scientists are working on the role of antioxidants to meet this challenge. However, research is lacking on the role of antioxidant enzymes and their isoforms in the non-compatible pathogen and host plant interaction and resistance mechanisms incapsicumvarieties. The present study was conducted to ascertain the defensive role of antioxidant enzymes and their isoforms in chilli varieties Hybrid, Desi, Serrano, Padron, and Shehzadi against bacterial spot disease-inducedXanthomonassp. The seedlings were inoculated with bacterial pathogen @ 107 CFU/mL, and samples were harvested after regular intervals of 24 h for 4 days followed by inoculation. Total plant proteins were extracted in phosphate buffer and quantified through Bradford assay. The crude protein extracts were analyzed through quantitative enzymatic assays in order to document activity levels of various antioxidant enzymes, including peroxidase (POD), Catalase (CAT), Ascorbate peroxidase (APX), and Superoxide dismutase (SOD). Moreover, the profiles appearance of these enzymes and their isoforms were determined using native polyacrylamide gel electrophoresis (PAGE) analysis. These enzymes exhibited maximum activity in Hybrid (HiR) cultivar followed by Desi (R), Serrano (S), Padron, and Shehzadi (HS). Both the number of isoforms and expression levels were higher in highly resistant cultivars compared to susceptible and highly susceptible cultivars. The induction of POD, CAT, and SOD occurs at the early stages of growth in resistantCapsicumcultivars. At the same time, APX seems to make the second line of antioxidant defense mechanisms. We found that modulating antioxidant enzymes and isoforms activity at the seedling stage was an important mechanism for mitigating plant growth inhibition in the resistant ones.
Age-related iron accumulation and demyelination in the basal ganglia are closely related to verbal memory and executive functioning
Authors: Biel Davina , Steiger Tineke K. , Bunzeck Nico 
Published: May 2021

AbstractAge-related cognitive decline has been linked to alterations of the dopaminergic system and its subcortical trajectories. Recent work suggests a critical role of iron accumulation within the basal ganglia (BG) in verbal memory performance, and increased iron levels have been related to demyelination. However, the specificity of age-related iron increases with respect to cognitive functions remains unclear. Therefore, we investigated the interplay of age, cognitive performance, and structural integrity of the BG. In total, 79 healthy older participants underwent a broad cognitive assessment (fluid and crystallized intelligence, verbal and numeric memory, processing speed, executive functions) and structural MRI. As expected, performance in most cognitive tests had a negative relationship with age. Moreover, BG grey matter volume and magnetization transfer (MT, indicative of myelin) decreased, and R2* (indicative of iron) increased with age. Importantly, R2* and demyelination negatively correlated with verbal memory and executive functions. Within the SN/VTA, age correlated negatively with MT, but there was no clear evidence in favor of a relationship between behavior and R2* or MT. Our results suggest that age-related increases in iron and demyelination within the BG, which are part of a fronto-striatal network, not only impact on verbal memory but also executive functions.
Simulation of gas transport in a landfill with layered new and old municipal solid waste
Authors: Zhang Tao , Shi Jianyong , Wu Xun , Lin Hai , Li Xiulei 
Published: May 2021

AbstractAverage biodegradation rate of newly filled municipal solid waste (MSW) in landfills is relatively fast, and the landfill gas produced by the new MSW biodegradation can cause great variations in gas pressure. To predict the gas pressure distribution in the MSW layer, a one-dimensional gas transport model is established in this study. The following factors are considered in this model: (1) the variation of gas permeability with depth; (2) the anisotropy ratio of gas permeability; (3) the settlement caused by waste biodegradation. Furthermore, a single peak model for gas production is applied as the source term of gas production. The equation for settlement caused by waste biodegradation is presented, and the time of peak gas production rate is obtained by fitting the settlement of the newly filled layer. The stratification of the unsaturated and saturated regions is taken into account by distinguishing the difference in gas saturation. The layering of the new and old waste layers is considered by distinguishing the difference in the length of time that waste has been degraded to produce gas. Based on the method of numerical calculation, the gas pressure distribution in the landfill with layered new and old MSW is well simulated. The position where the maximum gas pressure occurs is found. The sensitivity analysis shows that the influence of the anisotropy ratio on gas pressure distribution is more significant.
Broad individual immersion-scattering of respiratory compliance likely substantiates dissimilar breathing mechanics
Authors: Castagna Olivier , Michoud Guillaume , Prevautel Thibaut , Delafargue Antoine , Schmid Bruno , Similowski Thomas , Regnard Jacques 
Published: May 2021

AbstractHead-out water immersion alters respiratory compliance which underpins defining pressure at a “Lung centroid” and the breathing “Static Lung Load”. In diving medicine as in designing dive-breathing devices a single value of lung centroid pressure is presumed as everyone’s standard. On the contrary, we considered that immersed respiratory compliance is disparate among a homogenous adult group (young, healthy, sporty). We wanted to substantiate this ample scattering for two reasons: (i) it may question the European standard used in designing dive-breathing devices; (ii) it may contribute to understand the diverse individual figures of immersed work of breathing. Resting spirometric measurements of lung volumes and the pressure–volume curve of the respiratory system were assessed for 18 subjects in two body positions (upright Up, and supine Sup). Measurements were taken in air (Air) and with subjects immersed up to the sternal notch (Imm). Compliance of the respiratory system (Crs) was calculated from pressure–volume curves for each condition. A median 60.45% reduction in Crs was recorded between Up-Air and Up-Imm (1.68 vs 0.66 L/kPa), with individual reductions ranging from 16.8 to 82.7%. We hypothesize that the previously disregarded scattering of immersion-reduced respiratory compliance might participate to substantial differences in immersed work of breathing.
Expression patterns of major genes in fatty acid synthesis, inflammation, oxidative stress pathways from colostrum to milk in Damascus goats
Authors: Yakan Akın , Özkan Hüseyin , Çamdeviren Baran , Kaya Ufuk , Karaaslan İrem , Dalkiran Sevda 
Published: May 2021

AbstractThe molecular regulation of milk secretion and quality in the transition period from colostrum to milk in goats is largely unknown. In the present study, mammary gland secretion of goats was collected in 0th, 4th, 7th, 14th and 28th days after parturition. In addition to composition and fatty acid profile of colostrum or milk,FASN,SCD,ACACA,COX-2,NRF2,TLR2,NF-kB,LTFandPTX3genes expression patterns were determined from milk somatic cells. While somatic cell count (SCC), malondialdehyde (MDA), fat, fat-free dry matter, protein and lactose were highest as expression levels of the oxidative and inflammatory genes, freezing point and electrical conductivity were lowest in colostrum. With the continuation of lactation, most of the fatty acids, n3 ratio, and odour index increased but C14:0 and C16:0 decreased. WhileFASNwas upregulated almost threefolds in 14th day,ACACAwas upregulated more than fivefolds in 7th and 14th days. Separately, the major genes in fatty acid synthesis, inflammation and oxidative stress were significantly associated with each other due to being positively correlated. MDA was positively correlated with SCC and some of the genes related inflammation and oxidative stress. Furthermore, significant negative correlations were determined between SCC and fatty acid synthesis related genes. With this study, transition period of mammary secretion was particularly clarified at the molecular levels in Damascus goats.
Adaptation to chronic drought modifies soil microbial community responses to phytohormones
Authors: Sayer Emma J. , Crawford John A. , Edgerley James , Askew Andrew P. , Hahn Christoph Z. , Whitlock Raj , Dodd Ian C. 
Published: May 2021

AbstractDrought imposes stress on plants and associated soil microbes, inducing coordinated adaptive responses, which can involve plant–soil signalling via phytohormones. However, we know little about how microbial communities respond to phytohormones, or how these responses are shaped by chronic (long-term) drought. Here, we added three phytohormones (abscisic acid, 1-aminocyclopropane-1-carboxylic acid, and jasmonic acid) to soils from long-term (25-year), field-based climate treatments to test the hypothesis that chronic drought alters soil microbial community responses to plant stress signalling. Phytohormone addition increased soil respiration, but this effect was stronger in irrigated than in droughted soils and increased soil respiration at low phytohormone concentrations could not be explained by their use as substrate. Thus, we show that drought adaptation within soil microbial communities modifies their responses to phytohormone inputs. Furthermore, distinct phytohormone-induced shifts in microbial functional groups in droughted vs. irrigated soils might suggest that drought-adapted soil microorganisms perceive phytohormones as stress-signals, allowing them to anticipate impending drought.
Multivariate covalent organic frameworks boosting photocatalytic hydrogen evolution
Authors: Zhou Ting , Huang Xingye , Mi Zhen , Zhu Yunyang , Wang Rong , Wang Changchun , Guo Jia 
Published: May 2021

High-quality multivariate COFs were synthesized with an aminocatalytic solvothermal method. They can achieve higher photocatalytic H2 evolution rates than the parent homo-COFs by adjusting the benzothiadiazole-containing components.
Evolving Science to Inform Emerging Concussion Practices
Authors: Chesnutt James C. 
Published: May 2021

PurposeThis article describes two concussion models built on the current state of science that help illustrate the complicated interactions among the multiple factors that drive concussion symptoms. Consideration of these models remind practitioners, including speech-language pathologists, to attend to factors that increase the risk of patients developing prolonged symptoms, as well as attend to symptoms that result from various interactions and may differentially respond to specific treatments. In particular, the models encourage personalized or precision medicine and the implementation of targeted, coordinated therapies.
The Cultural and Diagnostic Appropriateness of Standardized Assessments for Dual Language Learners: A Focus on Jamaican Preschoolers
Authors: Karem Rachel Wright , Washington Karla N. 
Published: May 2021

PurposeThe aim of this study was to investigate the appropriateness of standardized assessments of expressive grammar and vocabulary in a sample of preschool-age dual language learners (DLLs) who use Jamaican Creole (JC) and English. Adult models from the same linguistic community as these children were used to inform culturally and linguistically appropriate interpretation of children's responses to a standardized assessment.MethodJC-English–speaking preschoolers (n= 176) and adults (n= 33) completed the Word Structure and Expressive Vocabulary subtests of the Clinical Evaluation of Language Fundamentals Preschool–Second Edition. Adults' responses were used to develop an adapted scoring procedure that considered the influence of JC linguistic features on responses. DLLs' responses scored using the standard English and adapted JC procedures were compared.ResultsJC–English DLLs and adults used similar linguistic structures in response to subtest questions. DLLs' scores differed significantly from the standardized sample on both subtests. Preschoolers received higher raw and corresponding standard scores with adapted scoring compared to standard scoring. Adapted scoring that made use of adult models yielded high classification accuracy at a rate of 93.8% for Word Structure and 92.1% for Expressive Vocabulary.ConclusionsAdapting standardized assessment scoring procedures using adult models may offer an ecologically valid approach to working with DLL preschoolers that can support a more accurate assessment of language functioning. These findings suggest that the use of standardized assessments for bilingual JC–English speakers requires a culturally responsive approach.Supplemental Materialhttps://doi.org/10.23641/asha.14403026
Constraining the AGN duty cycle in the cool-core cluster MS 0735.6+7421 with LOFAR data
Authors: Biava Nadia , Brienza Marisa , Bonafede Annalisa , Gitti Myriam , Bonnassieux Etienne , Harwood Jeremy , Edge Alastair C. , Riseley Christopher J. , Vantyghem Adrian 
Published: May 2021

Context.MS 0735.6+7421 is a galaxy cluster that hosts a central radio galaxy with a very steep spectrum. The spectrum is produced by one of the most powerful known jetted active galactic nuclei (AGN). The radio plasma, ejected at nearly light speed from the central AGN, has displaced the intra-cluster medium, leaving two pairs of cavities observable in the X-ray. The cavities are associated with two different outbursts and have distributed energy to the surrounding medium. While the age of the cavities has previously been estimated from the X-rays, no confirmation from radio data is available. Furthermore, the radio spectrum has only been derived from integrated flux density measurements so far, and the spatial distribution that would help us to understand the nature of this source is still lacking.Aims.We perform for the first time a detailed, high-resolution spectral study of the source at radio frequencies and investigate its duty cycle. We compare this with previous X-ray estimates.Methods.We used new observations at 144 MHz produced with the LOw Frequency ARray (LOFAR) together with archival data at higher frequencies (235, 325, 610, 1400, and 8500 MHz), to investigate the spectral properties of the source. We also used radiative models to constrain the age of the source.Results.At the LOFAR frequency, the source presents two large outer radio lobes that are wider than at higher frequencies, and a smaller intermediate lobe that is located south-west of the core. A new inspection of X-ray data allowed us to identify an intermediate cavity that is associated with this lobe. It indicates a further phase of jet activity. The radio lobes have a steep spectrum even at LOFAR frequencies, reachingα144610= 2.9 in the outer lobes andα144610= 2.1 in the intermediate lobe. Fitting the lobe spectra using a single injection model of particle ageing, we derived a total age of the source between 170 and 106 Myr. This age agrees with the buoyancy and sound-crossing timescales derived from X-ray data. The resolution of the spectral age map we performed allows us to reconstruct the duty cycle of the source. In three phases of jet activity, the AGN was active for most of the time with only brief quiescent phases that ensured the repeated heating of the central gas. Finally, we estimated the minimum energy inside the outer lobes. We find that a source of additional pressure support must be present to sustain the bubbles against the pressure of the external medium.