bluuebunny/crossref_metadata_2025_split huggingface dataset:
Voice Cues Influence Children’s Assessment of Adults’ Occupational Competence
Authors: Cartei Valentina , Oakhill Jane , Garnham Alan , Banerjee Robin , Reby David 
Published: February 2021

AbstractThe adult voice is a strong bio-social marker for masculinity and femininity. In this study we investigated whether children make gender stereotypical judgments about adults’ occupational competence on the basis of their voice. Forty-eight 8- to 10- year olds were asked to rate the competence of adult voices that varied in vocal masculinity (by artificially manipulating voice pitch) and were randomly paired with 9 occupations (3 stereotypically male, 3 female, 3 gender-neutral). In line with gender stereotypes, children rated men as more competent for the male occupations and women as more competent for the female occupations. Moreover, children rated speakers of both sexes with feminine (high-pitched) voices as more competent for the female occupations. Finally, children rated men (but not women) with masculine (low-pitched) voices as more competent for stereotypically male occupations. Our results thus indicate that stereotypical voice-based judgments of occupational competence previously identified in adults are already present in children, and likely to affect how they consider adults and interact with them in their social environment.
Improved optic disc and cup segmentation in Glaucomatic images using deep learning architecture
Authors: Mangipudi Partha Sarathi , Pandey Hari Mohan , Choudhary Ankur 
Published: February 2021

AbstractGlaucoma is an ailment causing permanent vision loss but can be prevented through the early detection. Optic disc to cup ratio is one of the key factors for glaucoma diagnosis. But accurate segmentation of disc and cup is still a challenge. To mitigate this challenge, an effective system for optic disc and cup segmentation using deep learning architecture is presented in this paper. Modified Groundtruth is utilized to train the proposed model. It works as fused segmentation marking by multiple experts that helps in improving the performance of the system. Extensive computer simulations are conducted to test the efficiency of the proposed system. For the implementation three standard benchmark datasets such as DRISHTI-GS, DRIONS-DB and RIM-ONE v3 are used. The performance of the proposed system is validated against the state-of-the-art methods. Results indicate an average overlapping score of 96.62%, 96.15% and 98.42% respectively for optic disc segmentation and an average overlapping score of 94.41% is achieved on DRISHTI-GS which is significant for optic cup segmentation.
Coherence of PRNU weighted estimations for improved source camera identification
Authors: Bruni Vittoria , Tartaglione Michela , Vitulano Domenico 
Published: February 2021

AbstractThis paper presents a method for Photo Response Non Uniformity (PRNU) pattern noise based camera identification. It takes advantage of the coherence between different PRNU estimations restricted to specific image regions. The main idea is based on the following observations: different methods can be used for estimating PRNU contribution in a given image; the estimation has not the same accuracy in the whole image as a more faithful estimation is expected from flat regions. Hence, two different estimations of the reference PRNU have been considered in the classification procedure, and the coherence of the similarity metric between them, when evaluated in three different image regions, is used as classification feature. More coherence is expected in case of matching, i.e. the image has been acquired by the analysed device, than in the opposite case, where similarity metric is almost noisy and then unpredictable. Presented results show that the proposed approach provides comparable and often better classification results of some state of the art methods, showing to be robust to lack of flat field (FF) images availability, devices of the same brand or model, uploading/downloading from social networks.
A cellular automata rule placing a maximal number of dominoes in the square and diamond
Authors: Hoffmann Rolf , Désérable Dominique , Seredyński Franciszek 
Published: February 2021

AbstractThe objective is to demonstrate that a probabilistic cellular automata rule can place reliably a maximal number of dominoes in different active area shapes, exemplarily evaluated for the square and diamond. The basic rule forms domino patterns, but the number of dominoes is not necessarily maximal and the patterns are not always stable. It works with templates derived from domino tiles. The first proposed enhancement (Rule Option 1) can form always stable patterns. The second enhancement (Rule Option 2) can maximize the number of dominoes, but the reached patterns are not always stable. All rules drive the evolution by specific noise injection.
Development and application of reverse genetic technology for the influenza virus
Authors: Li Ziquan , Zhong Liping , He Jian , Huang Yong , Zhao Yongxiang 
Published: February 2021

AbstractInfluenza virus is a common virus in people's daily lives, and it has certain infectivity in humans and animals. Influenza viruses have the characteristics of a high mutation rate and wide distribution. Reverse genetic technology is primarily used to modify viruses at the DNA level through targeted modification of the virus cDNA. Genetically modified influenza viruses have a unique advantage when researching the transmission and pathogenicity of influenza. With the continuous development of oncolytic viruses in recent years, studies have found that influenza viruses also have certain oncolytic activity. Influenza viruses can specifically recognize tumor cells; activate cytotoxic T cells, NK cells, dendritic cells, etc.; and stimulate the body to produce an immune response, thereby killing tumor cells. This article will review the development and application of influenza virus reverse genetic technology.
Modelling of different circular end-of-use scenarios for smartphones
Authors: Pamminger Rainer , Glaser Sebastian , Wimmer Wolfgang 
Published: February 2021

Abstract
Purpose
Repairing, refurbishing and remanufacturing are three strategies of the Circular Economy (CE), aiming at closing product cycles and maintaining materials and resources in the product cycle as long as possible. This paper analyses the environmental impacts of these three circular end-of-use scenarios (repairing, refurbishing and part remanufacturing) when performed on a common, “non-circular” smartphone. The underlying data used for this paper partly have been result of the Horizon 2020 project sustainablySMART, where circular product concepts have been developed and analysed in detail.

Methods
To analyse the environmental impacts of different circular end-of-use scenarios of smartphones, a Life Cycle Assessment (LCA) is performed. For considering the impact of a smartphone’s first life (e.g. materials, production), an economic allocation is used.
Since the goal of the study was to better understand the environmental impacts of processing routes that enable multiple life cycles of a product, allocation according to the economic value is applied instead of applying system expansion. As system expansion provides just an aggregated view of the first and second product life cycles and no decision support at the end of the first life regarding the relevant CE strategy can be given. The economic allocation is based on the ratio between the residual market value and the original price from the scenario’s input stream of smartphones of the respective end-of-use scenario.
To reach comparability of the results, a second-use-time-parameter is defined for each scenario. This parameter takes into account that the second use time reaches only a certain share from the average smart phone use time.

Results
This study shows that through all three circular strategies, a reduction in the investigated impact categories—Global Warming Potential (GWP) and Abiotic Depletion Potential (ADP)—can be achieved.

Conclusions
The analysed end-of-use scenarios repairing and refurbishing show the highest potential for smartphones in terms of Circular Economy, as most of the environmental impacts can be allocated to the device production, and the impact of additional steps to perform CE-strategies (e.g. collection of discarded phones, refurbishing) is rather low.
Battle of the Java Sea: One Event, Multiple Sites, Values and Views
Authors: Manders M. R. , de Hoop R. W. , Adhityatama S. , Bismoko D. S. , Syofiadisna P. , Haryanto D. 
Published: February 2021

AbstractThree Dutch naval ships, HNLMS De Ruyter, HNLMS Java and HNLMS Kortenaer, were lost during the Battle of the Java Sea on 27 February 1942, claiming the lives of 915 sailors. Although the ships were relocated in 2002, no official action was taken until 2016 when an international diving team from the Karel Doorman Foundation discovered that the warships had disappeared. This created tension between the government of Indonesia and those countries that had lost ships in the archipelago, especially the Netherlands. A three-track cooperation agreement was set up to investigate the disappearance of the three Dutch wrecks with the aim of understanding what had happened, in order to create a better basis for cooperation in the future. The management and protection of shipwrecks from WWII is very complicated, because of the different values that stakeholders attach to them. Only with the proper understanding and consideration of the different values or significance WWII shipwrecks hold for different stakeholders can new ways of managing these complex sites be developed that have long-term effectiveness. This paper argues that different stakeholder groups from both the flag and the coastal state must work together on this issue.
Reducing Inappropriate Proton Pump Inhibitors Use for Stress Ulcer Prophylaxis in Hospitalized Patients: Systematic Review of De-Implementation Studies
Authors: Orelio Claudia C. , Heus Pauline , Kroese-van Dieren Judith J , Spijker René , van Munster Barbara C. , Hooft Lotty 
Published: February 2021

Abstract
Background
A large proportion of proton pump inhibitor (PPI) prescriptions, including those for stress ulcer prophylaxis (SUP), are inappropriate. Our study purpose was to systematically review the effectiveness of de-implementation strategies aimed at reducing inappropriate PPI use for SUP in hospitalized, non-intensive care unit (non-ICU) patients.

Methods
We searched MEDLINE and Embase databases (from inception to January 2020). Two authors independently screened references, performed data extraction, and critical appraisal. Randomized trials and comparative observational studies were eligible for inclusion. Criteria developed by the Cochrane Effective Practice and Organisation of Care (EPOC) group were used for critical appraisal. Besides the primary outcome (inappropriate PPI prescription or use), secondary outcomes included (adverse) pharmaceutical effects and healthcare use.

Results
We included ten studies in this review. Most de-implementation strategies contained an educational component (meetings and/or materials), combined with either clinical guideline implementation (n = 5), audit feedback (n = 3), organizational culture (n = 4), or reminders (n = 1). One study evaluating the de-implementation strategy effectiveness showed a significant reduction (RR 0.14; 95% CI 0.03–0.55) of new inappropriate PPI prescriptions. Out of five studies evaluating the effectiveness of de-implementing inappropriate PPI use, four found a significant reduction (RR 0.21; 95% CI 0.18–0.26 to RR 0.76; 95% CI 0.68–0.86). No significant differences in the occurrence of pharmaceutical effects (n = 1) and in length of stay (n = 3) were observed. Adverse pharmaceutical effects were reported in two studies and five studies reported on PPI or total drug costs. No pooled effect estimates were calculated because of large statistical heterogeneity between studies.

Discussion
All identified studies reported mainly educational interventions in combination with one or multiple other intervention strategies and all interventions were targeted at providers. Most studies found a small to moderate reduction of (inappropriate) PPI prescriptions or use.
Association between blood cadmium levels and the risk of osteopenia and osteoporosis in Korean post-menopausal women
Authors: Kim Eun-San , Shin Sangah , Lee Yoon Jae , Ha In-Hyuk 
Published: February 2021

Abstract

Summary

We aimed to investigate the association between cadmium levels and the risk of osteopenia and osteoporosis in Korean post-menopausal women. There was a significant positive association between cadmium levels and the risk of osteopenia and osteoporosis, but further studies for dose response are required.

Purpose
Cadmium exposure can exert detrimental effects on bone health, particularly in post-menopausal women. However, previous studies have failed to report an association in Korean post-menopausal women. We aimed to investigate the association between cadmium levels and the risk of osteopenia and osteoporosis in Korean post-menopausal women.

Methods
In total, 5432 participants from the 4th and 5th Korean National Health and Nutrition Examination Survey (KNHANES) were randomly sampled for measurements of heavy metal concentrations in the blood, bone mass density (BMD), and nutrient intake. We analyzed data for 1031 post-menopausal women ≥50 years of age. Blood cadmium levels were categorized into quartiles, and a multinomial logistic regression model was used for analysis.

Results
There was a significant positive association between cadmium levels and the risk of osteopenia and osteoporosis, but the odds ratio (OR) at the 4th level was lower than that at the 3rd level (OR and 95% confidence interval (CI) for osteopenia: 2nd quartile: 1.24, 0.88-1.74; 3rd quartile: 3.22, 2.24-4.64; 4th quartile: 1.27, 0.87-1.85; P for trend <0.001; OR and 95% CI for osteoporosis: 2nd quartile: 1.54, 1.05-2.25; 3rd quartile: 3.63, 2.31-5.69; 4th quartile: 1.70, 1.03-2.81; P for trend <0.001). This trend was consistent in the sensitivity analysis.

Conclusion
Our findings suggest that there is an association between blood cadmium levels and the risk of osteopenia and osteoporosis in Korean post-menopausal women. However, further prospective studies are required to determine whether there is a dose-response relationship and address potential selection bias, especially in patients with femoral neck osteoporosis.
Centric Allometry: Studying Growth Using Landmark Data
Authors: Bookstein Fred L. 
Published: February 2021

AbstractThe geometric morphometric (GMM) construction of Procrustes shape coordinates from a data set of homologous landmark configurations puts exact algebraic constraints on position, orientation, and geometric scale. While position as digitized is not ordinarily a biologically meaningful quantity, and orientation is relevant mainly when some organismal function interacts with a Cartesian positional gradient such as horizontality, size per se is a crucially important biometric concept, especially in contexts like growth, biomechanics, or bioenergetics. “Normalizing” or “standardizing” size (usually by dividing the square root of the summed squared distances from the centroid out of all the Cartesian coordinates specimen by specimen), while associated with the elegant symmetries of the Mardia–Dryden distribution in shape space, nevertheless can substantially impeach the validity of any organismal inferences that ensue. This paper adapts two variants of standard morphometric least-squares, principal components and uniform strains, to circumvent size standardization while still accommodating an analytic toolkit for studies of differential growth that supports landmark-by-landmark graphics and thin-plate splines. Standardization of position and orientation but not size yields the coordinates Franz Boas first discussed in 1905. In studies of growth, a first principal component of these coordinates often appears to involve most landmarks shifting almost directly away from their centroid, hence the proposed model’s name, “centric allometry.” There is also a joint standardization of shear and dilation resulting in a variant of standard GMM’s “nonaffine shape coordinates” where scale information is subsumed in the affine term. Studies of growth allometry should go better in the Boas system than in the Procrustes shape space that is the current conventional workbench for GMM analyses. I demonstrate two examples of this revised approach (one developmental, one phylogenetic) that retrieve all the findings of a conventional shape-space-based approach while focusing much more closely on the phenomenon of allometric growth per se. A three-part Appendix provides an overview of the algebra, highlighting both similarities to the Procrustes approach and contrasts with it.
Patient Reported Outcomes in Large Vessel Vasculitides
Authors: Robson Joanna , Mackie Sarah , Hill Catherine 
Published: February 2021

Abstract
Purpose of Review
The goal of this paper is to review current and future uses of patient-reported outcomes in large vessel vasculitis. The large vessel vasculitides comprise Giant Cell Arteritis and Takayasu arteritis; both are types of systemic vasculitis which affect the larger blood vessels. Patient-reported outcomes (PROs) capture the impact of these diseases on health-related quality of life.

Recent Findings
Generic PROs such as the SF-36 are currently used to compare HRQOL of people with GCA and TAK within clinical trials and observational studies and to make comparisons with the general population and HRQoL in other diseases. The development of a disease-specific PRO for GCA is currently underway. Beyond clinical trials, there is much interest in the use of PROs within routine clinical care, particularly E-PROs for remote use.

Summary
Further work will be needed to complete the development of disease-specific PROs for people with large vessel vasculitis and to establish feasibility, acceptability, and utility of E-PROs.
Neighbourhoods and Workplaces: Are They Related to the Fertility of Immigrants and Their Descendants? A Register-Based Study of Finland, 1999–2014
Authors: Puur Allan , Rahnu Leen , Tammaru Tiit 
Published: February 2021

AbstractAn increasing number of studies point to the existence of fertility differences between immigrants and those who are native to the receiving countries. However, despite a large body of literature covering a wide range of settings, there is a lack of research into the factors that may underlie the observed differentials. In this article, we focus on the role of population composition in residential neighbourhoods and workplaces, which are assumed to influence the convergence of the fertility patterns of immigrants with those of the host country. The study is based on individual-based register data for the residential population of Finland from 1999 to 2014. We use discrete-time event history models to analyse transitions to first, second, and third births among immigrant women and their descendants of African and Middle Eastern origin whose fertility patterns are markedly different from those of the host society. We investigate whether the proportion of co-ethnic immigrants in residential neighbourhoods and workplaces is related with the fertility adaptation among that high-fertility group. Our results suggest that among them, a higher concentration of co-ethnic immigrants in the neighbourhood is associated with an elevated propensity of having a second and third child. The association persists among child migrants and the second generation. However, a similar association is not observed between fertility and the workplace context.
Fear of missing out and self-esteem as mediators of the relationship between maximization and problematic smartphone use
Authors: Servidio Rocco 
Published: February 2021

AbstractProblematic smartphone use (PSU), which involves an excessive and uncontrolled use of smartphones, thereby causing daily-life disturbance, has been associated with a range of negative outcomes including anxiety, depression, and deficits in social relationships. However, the relationship between PSU and maximization, which could be an explanatory factor, has not yet been thoroughly studied. Drawing on the Interaction-Person-Affect-Cognition-Execution (I-PACE) model, the current study aimed to investigate the association between PSU and maximization with the assumption that fear of missing out (FoMO) and self-esteem could mediate this relationship. Empirical data were gathered from 277 Italian university students who completed an online survey. Correlation analysis and structural equation modelling (SEM) were used to investigate the relationships among the variables. The results showed that PSU, maximization, and FoMO were positively correlated; whereas maximization and self-esteem were negatively correlated. Furthermore, FoMO and self-esteem partially mediated that relationship, suggesting that participant maximizers experience more FoMO, especially when the participants have fear of missing out on potentially “better” alternatives to social experiences and exhibit low self-esteem. Thus, higher FoMO and low self-esteem can be a driver of PSU. Finally, this study provides new insights about how maximization may have an impact on the development of addictive behaviour such as PSU.
Occupational exposure of health care personnel to SARS-CoV-2 particles in the intensive care unit of Tehran hospital
Authors: Yarahmadi R. , Bokharaei-Salim F. , Soleimani-Alyar S. , Moridi P. , Moradi-Moghaddam O. , Niakan-Lahiji M. , Darvishi M.-M. , Golmahammadi S. , Mousavi S. A. J. , Ebrahimi H. , Ashtarinezad A. , Farshad A.-A. , Jonidi-Jafari A. , Kiani S. J. , Garshasbi S. , Mehrzadi S. 
Published: February 2021

AbstractThe outbreak of SARS-CoV-2 (COVID-19) has attracted much attention to study its possible presence and airborne transmission. The possibility of COVID-19 airborne transmission in indoor environments is debatable. The present study examined the concentration of viral RNA-containing particles produced directly or indirectly by breathing or coughing of confirmed COVID-19 patients or by carriers without symptoms. Some studies do not accept this method of transmission (COVID-19 airborne transmission). The present study aimed to measure the possible exposure of health care personnel to SARS-CoV-2 particles that may have been suspended in the air to respond to the hypothesis of COVID-19 airborne transmission. Airborne particle sampling was performed using impingement method based on NIOSH (chapter BA) and ASHRAE. Selection of sampling sections was in line with the WHO guidelines. The samples were analyzed using RT-PCR technique. Based on the given results, airborne particles of COVID-19 may present in the air and affect the health of hospital personnel. In fact, the analysis of gene expression in ambient conditions and thereby aerosol transmission of SARS-CoV-2 through air is possible and may lead to occupational exposure of health care personnel. Furthermore, it was found that airborne emission of COVID-19 through the breathing zone of patients, particularly in ICU wards with confirmed cases of COVID-19, may be higher than in other ICU wards. Also, the demonstrated results showed that there is a possibility of reaerosolization (reintroduction) of previously airborne SARS-CoV-2 particles into the atmosphere due to health care personnel frequently walking between different wards and stations of ICU.