bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Postoperative Clinical Outcomes With Sarcopenia, Frailty, and Nutritional Status in Older Patients With Colorectal Cancer: Protocol for a Prospective Cohort Study
Authors: Humphry Nia Angharad , Wilson Thomas , Cox Michael Christian , Carter Ben , Arkesteijn Marco , Reeves Nicola Laura , Brakenridge Scott , McCarthy Kathryn , Bunni John , Draper John , Hewitt Jonathan 
Published: March 2021

Background
Older patients account for a significant proportion of patients undergoing colorectal cancer surgery and are vulnerable to a number of preoperative risk factors that are not often present in younger patients. Further, three preoperative risk factors that are more prevalent in older adults include frailty, sarcopenia, and malnutrition. Although each of these has been studied in isolation, there is little information on the interplay between them in older surgical patients. A particular area of increasing interest is the use of urine metabolomics for the objective evaluation of dietary profiles and malnutrition.

Objective
Herein, we describe the design, cohort, and standard operating procedures of a planned prospective study of older surgical patients undergoing colorectal cancer resection across multiple institutions in the United Kingdom. The objectives are to determine the association between clinical outcomes and frailty, nutritional status, and sarcopenia.

Methods
The procedures will include serial frailty evaluations (Clinical Frailty Scale and Groningen Frailty Indicator), functional assessments (hand grip strength and 4-meter walk test), muscle mass evaluations via computerized tomography morphometric analysis, and the evaluation of nutritional status via the analysis of urinary dietary biomarkers. The primary feasibility outcome is the estimation of the incidence rate of postoperative complications, and the primary clinical outcome is the association between the presence of postoperative complications and frailty, sarcopenia, and nutritional status. The secondary outcome measures are the length of hospital stay, 30-day hospital readmission rate, and mortality rate at days 30 and 90.

Results
Our study was approved by the National Health Service Research Ethics Committee (reference number: 19/WA/0190) via the Integrated Research Application System (project ID: 231694) prior to subject recruitment. Cardiff University is acting as the study sponsor. Our study is financially supported through an external, peer-reviewed grant from the British Geriatrics Society and internal funding resources from Cardiff University. The results will be disseminated through peer-review publications, social media, and conference proceedings.

Conclusions
As frailty, sarcopenia, and malnutrition are all areas of common derangement in the older surgical population, prospectively studying these risk factors in concert will allow for the analysis of their interplay as well as the development of predictive models for those at risk of commonly tracked surgical complications and outcomes.

International Registered Report Identifier (IRRID)
PRR1-10.2196/16846
Immersive Virtual Reality and Ocular Tracking for Brain Mapping During Awake Surgery: Prospective Evaluation Study
Authors: Casanova Morgane , Clavreul Anne , Soulard Gwénaëlle , Delion Matthieu , Aubin Ghislaine , Ter Minassian Aram , Seguier Renaud , Menei Philippe 
Published: March 2021

BackgroundLanguage mapping during awake brain surgery is currently a standard procedure. However, mapping is rarely performed for other cognitive functions that are important for social interaction, such as visuospatial cognition and nonverbal language, including facial expressions and eye gaze. The main reason for this omission is the lack of tasks that are fully compatible with the restrictive environment of an operating room and awake brain surgery procedures.ObjectiveThis study aims to evaluate the feasibility and safety of a virtual reality headset equipped with an eye-tracking device that is able to promote an immersive visuospatial and social virtual reality (VR) experience for patients undergoing awake craniotomy.MethodsWe recruited 15 patients with brain tumors near language and/or motor areas. Language mapping was performed with a naming task, DO 80, presented on a computer tablet and then in 2D and 3D via the VRH. Patients were also immersed in a visuospatial and social VR experience.ResultsNone of the patients experienced VR sickness, whereas 2 patients had an intraoperative focal seizure without consequence; there was no reason to attribute these seizures to virtual reality headset use. The patients were able to perform the VR tasks. Eye tracking was functional, enabling the medical team to analyze the patients’ attention and exploration of the visual field of the virtual reality headset directly.ConclusionsWe found that it is possible and safe to immerse the patient in an interactive virtual environment during awake brain surgery, paving the way for new VR-based brain mapping procedures.Trial RegistrationClinicalTrials.gov NCT03010943; https://clinicaltrials.gov/ct2/show/NCT03010943.
NUTRACEUTICAL PROPERTIES OF GLUTEN-FREE CUPCAKES PREPARED BY GLUTEN-FREE COMPOSITE FLOUR
Authors: AKANSHA  , E. S. CHAUHAN 
Published: March 2021

Objective: The present study was aimed to evaluate the nutritional, phytochemical and antioxidant properties of all ratios of gluten-free composite flour-based cupcakes.
Methods: Composite flour was the blend of teff millet flour (TF), navy bean flour (NF) and watermelon seeds flour (WF). The variations of three composite flours were prepared as, A being (TF: NF: WF=45:45:10), B being (TF: NF: WF=55:35:10) and C being (TF: NF: WF=65:25:10) respectively. Moisture, ash, fat, fiber, protein and carbohydrate were analyzed in this study. Minerals like calcium, iron, phosphorus and zinc were also analyzed.
Results: The result of macronutrient and micronutrient of C ratio was moisture (28.1±0.2), ash (2.5±0.0), protein (12.2±0.3), fat (24.5±0.0), fiber (2.8±0.1) and carbohydrate (32.2±0.1 g/100g) respectively. Calcium (36.9±0.1), iron (7.5±0.0), zinc (3.8±0.2) and phosphorus (235.0±0.4 mg/100g) were also present in gluten-free Cupcakes. On the basis of the present study, it was found that gluten-free cupcakes contain different macro as well as micronutrients. It also has some phytochemicals such as flavonoids, saponins, tannin, glycocides and steroids.
Conclusion: The study result revealed that gluten-free Cupcakes had higher phenols content as well as antioxidant activity. The overall good amount of all nutrients found in the C ratio. The sensory evaluation of Cupcakes on a 9 point hedonic scale revealed that a ratio was more acceptable than the B and C ratio. Therefore, it can be beneficial for celiac diseases, hypertension, anemia, diabetes and cancer condition.
OVERVIEW ON METHODS OF SYNTHESIS OF NANOPARTICLES
Authors: PATIL NILESH , BHASKAR RAJVEER , VYAVHARE VISHAL , DHADGE RAHUL , KHAIRE VAISHNAVI , PATIL YOGESH 
Published: March 2021

In recent years, interest in the development of novel drug delivery systems using nanoparticles has gained more attention. The nanoparticles offer several advantages over other conventional drug delivery systems. Nanoparticles have gained importance in technological advancements due to their modifiable physical, chemical and biological properties with improved performance over their bulk foils. Nanoparticles can simply move in the body due to their small size and reach very complex organs through diverse routes. The high stability, controlled drug release makes nanoparticles the most suitable drug delivery system. Along with all these advantages, they offer variety in routes of administration. Both hydrophilic, as well as hydrophobic drugs, can be delivered in the form of nanoparticles. Nanoparticles have been used as a physical approach to modify and advance the pharmacokinetics and pharmacodynamics possessions of various types of drug molecules. Thesol-gel technique is a stress-free and very inexpensive process to formulate metal oxides and permits control over the doping process or adding of transition metals, as related to other research techniques. The study of different methods of synthesis of nanoparticles is essential to obtain desired nanoparticles with specific sizes and shapes. They are suitable candidates for various marketable and local applications, which include imaging, catalysis medical applications and environmental applications. This review mainly focuses on approaches used for the production of nanoparticles and different methods of synthesis of nanoparticles such as physical, chemical and biological method.
Collection of location data in criminal proceedings – European (the EU and Strasbourg) standards
Authors: Czerniak Dominika 
Published: March 2021

This article deals with the problem of collecting, retaining and processing location data for use in criminal proceedings. The collection of location data is an interference with the right to privacy (the Article 8 of the ECHR, the Article 7 of the Charter). However, such interference is permissible if it pursues the aims indicated in Article 8(2) of the ECHR (prevention of and fight against serious crime, protection of general security, national security). Therefore, the question arises as to when the procedural authorities may obtain location data (what offences may justify interference with the right to privacy) and what conditions should be met by national law with regard to this issue. The ECtHR and the CJEU are increasingly dealing with cases that concern the collection of location data in real time and data retention by telecommunications service providers. This requires an assessment of whether a European standard has now been developed and, if so, what is the standard?
PELATIHAN DAN PENDAMPINGAN PENGELOLAAN ADMINISTASI BUMDES DI DESA ELLAK DAYA KECAMATAN LENTENG
Authors: Tini Dwi Listia Rika , Yuliastina Roos 
Published: March 2021

BUMDes Assalam di Desa Ellak Daya telah beroperasi selama 1 tahun dalam bidang persewaan lapangan futsal dan persewaan ruko (toko) permanen, dan juga mengembangkan usaha galeri BUMDes untuk menjual hasil panen dan produk UMKM masyarakat setempat. Untuk meningkatkan pengembangan BUMDes dalam rangka penguatan ekonomi desa, maka perlu pengelolaan sistem administrasi BUMDes karena selama ini BUMDes tersebut belum memiliki standar administrasi dalam pengelolaan BUMDes. Metode yang digunakan dalam pengelolaan sistem administrasi tersebut yaitu melaksanakan pelatihan dan pendampingan kepada seluruh pengurus BUMDes Assalam yang berjumlah sembilan orang. Pelatihan dan pendampimgan tersebut berupa manajemen arsip / pengelolaan arsip yang baik dan benar melalui Sistem Informasi Manajemen (SIM) berbasis komputer, serta pelatihan dan pendampingan pembuatan Standart Oprasional Prosedur (SOP) pengelolaan usaha persewaan lapangan futsal dan pertokoan, SOP sistem manajemen penjualan hasil panen dan produk UMKM masyarakat desa Ellak Daya yang di jual di galeri BUMDes, SOP tugas dan fungsi para anggota BUMDes. Hasil yang dicapai setelah pelatihan ini adalah: (1) Pengelola BUMdes Assalam mampu mengelola arsip dengan berbasis komputer; (2) Pengelola BUMDes Assalam mampu menyusun SOP keuangan dari persewaan lapangan futsal dan toko, (3) Pengurus BUMDes memilki pemahaman yang benar tentang tugas dan fungsi dari masing-masing; (4) Pengelola BUMDes Assalam mampu menyusun laporan pembukuan dan pencatatan administrasi yang benar sehingga bisa memberikan pertanggungjawaban pengurus dalam penggunaan Dana Penyertaan Modal yang telah digulirkan pemerintah.
Iekļaušanās. Dažas epizodes Latvijas jūrnieku profesionālajās gaitās trimdā Rietumos
Authors: Beitlers Dāvis 
Published: March 2021

Šis raksts turpina saistītas tematikas publikāciju žurnāla iepriekšējā numurā un stāsta par tiem starpkaru Latvijas Republikas pilsoņiem, kuri Otrā pasaules kara un tā atskaņu laikā nonāca un palika Rietumu pasaulē, kur – jau kā trimdinieki – turpināja vai tikai sāka jūrnieka gaitas, pamazām iekļaujoties mītnes valstu saimnieciskajā un profesionālajā, sociālajā un sabiedriski politiskajā vidē un struktūrās. Rakstā iezīmētas dažas no problēmām, kas pavadīja latviešu jūrniekus – trimdiniekus šīs “ieaugšanas” gaitā, ieskicēti daži jūrnieku veiksmes stāsti un viena otra pētniecības problēma, kas ieaužas trimdas vēstures izpētes problemātikā kopumā.
Acreditação hospitalar e o enfrentamento ao covid-19
Authors: Novaes Humberto De Moraes 
Published: March 2021

Esta resenha histórica pretende recordar os desafios para implementar qualidade na assistência nos hospitais brasileiros. Várias iniciativas foram propostas nos últimos 30 anos, mas a realidade atual ainda demonstra a grande necessidade de que muitas ações se têm por fazer. Esperamos que o alerta trazido pelo coronavírus possa estimular as mudanças necessárias para estas transformações.Palavras-chave: Gestão de qualidade em saúde; Acreditação hospitalar; Pandemia pelo novo coronavíruis (2019-nCoV) ABSTRACTThis historical review intends to recall the challenges to implement quality of care in Brazilian hospitals. Several initiatives have been proposed in the past 30 years, but the current reality still demonstrates the great need for many actions to be done. We hope that the alert brought by the coronavirus can stimulate the necessary changes for these transformations.Keywords: Quality Management; Hospital accreditation; New Coronavirus Pandemic (2019-nCoV)
Influence of the principle of minimum potential energy on the distribution of density and gravitational energy of the Earth for the reference model PREM
Authors: Fys М.М. , Tserklevych А.L. 
Published: March 2021

From the point of view of modeling the internal structure of the Earth, its figure and evolution play an important role, which to one degree or another are associated with gravitational energy and the principle of its minimization. The realization of the minimum principle of potential for models of the distribution of the Earth’s density is the key in studies on the detection of inhomogeneous mass distribution. Achieving the minimum gravitational energy of the Earth is equivalent to the approximation of the internal structure to the hydrostatic state, and this condition is achieved due to variations in density. Therefore, for correct geophysical interpretation of gravimetric data, it is necessary to align the PREM (Preliminary Reference Earth Model) with harmonic coefficients of geopotential and minimum functional condition that determines gravitational energy, and only on this basis to estimate variations in density and tectonosphere. An algorithm for representing a piecewise continuous density distribution function in a spherical PREM model by Legendre polynomials is proposed in the paper to calculate the density, potential and energy distribution in an ellipsoidal planet using an additional condition — the minimum of gravitational energy. The use of such an algorithm made it possible to transform the spherically symmetric PREM model to a hydrostatically balanced state. It turned out that in the model obtained, the excess potential energy is concentrated in the inner and outer core of the Earth, and also insignificantly in the planet’s crust. The total energy E for the PREM reference model, which is subdivided into ellipsoidal layers, is 2.3364∙1024 erg, and in the modified PREM model after its correction for the hydrostatic component, it is 2.2828∙1024 erg. Estimation of density redistribution and identification of areas of their greatest change provide a mechanism for explaining the dynamic processes in the middle of the Earth.
IMPROVING ORGANIZATIONAL CITIZENSHIP BEHAVIOR (OCB) THROUGH STRENGTHENING ORGANIZATIONAL CLIMATE AND PERSONALITY
Authors: Yusnita Nancy , Sunaryo Widodo , Yulianti Sri 
Published: March 2021

Many kinds of research on Organizational Citizenship Behavior (OCB) had generated findings that OCB is considered one of the main ways to increase organizations’ effectiveness. This study examines factors that have a relationship with OCB, namely, organizational climate and personality. This study was conducted among Primary School teachers at Cileungsi District, Bogor, Indonesia. The sample for the study consisted of 152 permanent teachers derived randomly from its population which is 245 Primary School teachers. The study mainly utilized quantitative data (from questionnaires). Regression and correlational analysis were applied, with that the relationship among variables found. The findings revealed that the school organizational climate had a positive and significant relationship with OCB. Similarly, teachers’ personalities had a positive and significant relationship with OCB. Both school organizational climate and teachers’ personalities simultaneously had a strong positive and significant relationship with OCB. Further analysis was conducted to find out which indicators of those variables that had a dominant influence on OCB. Based on the indicator analysis results, this study proposed some recommendations toward Primary School Principals at Cileungsi District, Bogor to strengthen indicators of Organizational Climate and Personality that have a high coefficient of correlation with OCB. By strengthening those indicators it can be predicted will improve teachers’ OCB.
La narración autobiográfica como elemento escenográfico en la interpretación de la obra de arte
Authors: Fernández-Inglés Soledad 
Published: March 2021

La narración en clave autobiográfica es un instrumento que no solo se compenetra con la mediación para la comprensión del patrimonio en un código intercultural, sino que es un recurso fundamental para la ciudadanía activa, para la alfabetización crítica en la edad adulta y para la creación del sentido de pertenencia a un lugar. Este artículo recoge el uso que de ella hacen los Servicios Educativos del Museo de Arte Moderno y Contemporáneo de Bérgamo (GAMeC), una herramienta que ha pasado a formar parte de sus políticas de desarrollo y de inclusión social y cultural.
En 2014, la GAMeC puso en pie un proyecto en el ámbito del cual se ha creado un cruce entre la colección permanente, el patrimonio cultural inmaterial (memoria y tradición) y la identidad cultural. Su misión es la de dar vida a una narración que se transforme en puente y salga de la óptica del historiador del arte para que entre en la de la persona; por ello los objetivos son formar, experimentar y cohesionar. Salvaguardando los contenidos pero entrelazándolos en la vida cotidiana, el proyecto da voz a los objetos y a sus autores en diálogo con la vida de las personas, y en donde la historiadora de arte vigila para que nada quede fuera desde el punto de vista histórico-artístico
Predictors of postoperative atrial fibrillation
Authors: Kadyrova M. , Stepanova Yu. A. , Grinberg M. S. , Raguzina V. Yu. , Malyshenko E. S. , Shirokov V. S. , Popov V. A. , Revishvili A. Sh. 
Published: March 2021

Review purpose: to study the occurrence predictors of postoperative atrial fibrillation (PAF), effective predicting and treating methods according to global literature.Currently, PAF is considered one of the most frequent events among all cardiovascular complications as it develops in 30–65% of cases in patients after heart surgery. In recent decades, the PAF incidence has steadily increased despite advances in surgery and anesthesiology. PAF is a significant complication that affects the course of the postoperative period and requires special attention, since it leads to a longer hospital stay, increased treatment costs and can also lead to lethal outcomes in patients in this category. Considering PAF consequences, many studies have been performed to identify factors associated with the atrial fibrillation pathophysiology, to develop preventive measures aimed at treating high risk patients and minimize the side effects of antiarrhythmic drugs. The review and analysis of the global literature on the PAF causes, prevention and treatment are presented.
Building Green Hospital Model in Implementing Sustainable Development Goals in Vietnam
Authors: Thi Thu Hien Pham 
Published: March 2021

Sustainable development is not only a national goal but also a global concern as climate change and the impacts of environmental pollution are changing the quality of life and threatening human existence. Sustainable development goals are covered in all aspects of life, including medical activities and community health care. As a component of the health system, hospitals not only perform medical examination and treatment as well as research on treatment methods but also ensure the conditions for achieving sustainable development goals and other non-medical targets of the health sector. The paper focuses on analyzing the Green hospital model and the need to build this model in the implementation of the sustainable development goals.
Keywords
Sustainable Development, Health, Green Hospital, Policy, Green health ecosystem.
References
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