bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-Related Victimization, Racial Bias and Employment and Housing Disruption Increase Mental Health Risk Among U.S. Asian, Black and Latinx Adults
Authors: Fisher Celia B. , Tao Xiangyu , Liu Tingting , Giorgi Salvatore , Curtis Brenda 
Published: October 2021

Background:The mental health of racial/ethnic minorities in the U.S. has been disproportionately impacted by the COVID-19 pandemic. This study examined the extent to which disruptions in employment and housing, coronavirus-specific forms of victimization and racial bias independently and conjointly contributed to mental health risk among Asian, Black, and Latinx adults in the United States during the pandemic.Methods:This study reports on data from 401 Asian, Black, and Latinx adults (age 18–72) who participated in a larger national online survey conducted from October 2020–June 2021, Measures included financial and health information, housing disruptions and distress in response to employment changes, coronavirus related victimization distress and perceived increases in racial bias, depression and anxiety.Results:Asian participants had significantly higher levels of COVID-related victimization distress and perceived increases in racial bias than Black and Latinx. Young adults (&lt;26 years old) were more vulnerable to depression, anxiety, and coronavirus victimization distress than older respondents. Having at least one COVID-related health risk, distress in response to changes in employment and housing disruptions, pandemic related victimization distress and perceived increases in racial bias were positively and significantly related to depression and anxiety. Structural equation modeling indicated COVID-related increases in racial bias mediated the effect of COVID-19 related victimization distress on depression and anxiety.Conclusions:COVID-19 has created new pathways to mental health disparities among racial/ethnic minorities in the U.S. by exacerbating existing structural and societal inequities linked to race. Findings highlight the necessity of mental health services sensitive to specific challenges in employment and housing and social bias experienced by people of color during the current and future health crises.
Psychosocial Health and Physical Activity in People With Major Depression in the Context of COVID-19
Authors: Cody Robyn , Kreppke Jan-Niklas , Beck Johannes , Donath Lars , Eckert Anne , Imboden Christian , Hatzinger Martin , Holsboer-Trachsler Edith , Lang Undine E. , Ludyga Sebastian , Mans Sarah , Mikoteit Thorsten , Oswald Anja , Rogausch Anja , Schweinfurth Nina , Zahner Lukas , Faude Oliver , Gerber Markus 
Published: October 2021

Introduction: Major depression is a psychiatric disease associated with physical inactivity, which in turn affects mental and physical health. A randomized controlled trial is being implemented to facilitate physical activity in people with major depression. In March 2020, Swiss state authorities temporarily legislated a lockdown to contain the Coronavirus disease-19 (COVID-19), which influenced health, behavior and research. The aim of this study was to find out whether data gathered before and during/after the lockdown among in-patients with major depression differ with regard to psychosocial health, physical activity and related attitudes and to establish whether baseline data have been affected by the lockdown.Methods: This is a cross-sectional analysis within a randomized controlled trial. Physically inactive, adult in-patients diagnosed with major depression were recruited from four Swiss psychiatric clinics between January 2019 and December 2020. Psychosocial health was measured with questionnaires pertaining to stress, sleep and health-related quality of life. Physical activity was measured with the Simple Physical Activity Questionnaire. Explicit attitudes were measured with seven questionnaires pertaining to physical activity-related motivation and volition. Implicit attitudes toward physical activity were captured with a single target implicit association test.Results: The sample consisted of 165 participants (n = 119 before lockdown, n = 46 during/after lockdown). No statistically significant differences were found between in-patients with major depression assessed before and during/after the COVID-19 lockdown with regard to psychosocial health (stress, p = 0.51; sleep, p = 0.70; physical component of health-related quality of life, p = 0.55; mental component of health-related quality of life, p = 0.64), self-reported physical activity (p = 0.16) and explicit as well as implicit attitudes toward physical activity (p = 0.94). Hence, the COVID-19-induced lockdown seems not to have led to group differences.Conclusion: Baseline data gathered in in-patients suffering from major depression who are physically inactive upon admission to in-patient treatment in Switzerland seem to be unaffected by the COVID-19-induced lockdown. To assess changes in said population regarding psychosocial health and physical activity patterns over time, longitudinal data are needed.
Potential Value of Matrix Metalloproteinase-13 as a Biomarker for Osteoarthritis
Authors: Xin Xing , Tan Qizhao , Li Fang , Chen Zhongqiang , Zhang Ke , Li Feng , Yang Bin , Xing Zhili , Zhou Fang , Tian Yun , Lv Yang , Zhu Tengjiao 
Published: October 2021

Background: Emerging knowledge has highlighted the role of matrix metalloproteinase (MMP)-13 in osteoarthritis (OA); however, the suitability of MMP-13 as a biomarker for OA remains unclear. Therefore, this study aimed to assess the potential value of MMP-13 as a biomarker for OA.Methods: The study enrolled 51 patients, of which 33 had advanced varus OA and 18 did not have OA. Immunohistochemistry and western blotting analyses were performed to measure MMP-13 activity in the cartilage and subchondral bone of patients with OA. Enzyme-linked immunosorbent assay was used to measure serum MMP-13 levels in patients with or without OA. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was used to assess the association between serum MMP-13 levels and clinical symptoms. Furthermore, the association between serum MMP-13 levels and radiological severity of OA was evaluated using the Kellgren–Lawrence (KL) grading system. Finally, we built the proportional odds logistic regression models to evaluate serum MMP-13 levels as a potential predictor for OA.Results: MMP-13 levels were significantly higher in the severe-worn cartilage of the medial tibial plateau than in the relatively intact portion of the lateral cartilage (p &lt; 0.05). This was contrary to the findings for MMP-13 differential expression in the subchondral bone in knee OA (p &lt; 0.05). Patients with OA had significantly higher serum MMP-13 levels compared with patients without OA. Additionally, remarkable associations among serum MMP-13 levels, WOMAC scores, and KL grading scores were found in the end-stage OA. Furthermore, the subsequent analysis suggested that serum MMP-13 level was a significant predictor for OA.Conclusion: MMP-13 is valuable for diagnosing, measuring disease severity, and predicting OA in the advanced period of the disease, suggesting that it has potential possibility as a biomarker for OA. However, the underlying mechanisms and clinical application of MMP-13 as a biomarker for OA require to be further investigated.
Biomechanical Influences on Mesh-Related Complications in Incisional Hernia Repair
Authors: Kallinowski Friedrich , Ludwig Yannique , Gutjahr Dominik , Gerhard Christian , Schulte-Hörmann Hannah , Krimmel Lena , Lesch Carolin , Uhr Katharina , Lösel Philipp , Voß Samuel , Heuveline Vincent , Vollmer Matthias , Görich Johannes , Nessel Regine 
Published: October 2021

Aim: Hernia repair strengthens the abdominal wall with a textile mesh. Recurrence and pain indicate weak bonds between mesh and tissue. It remains a question which biomechanical factors strengthen the mesh-tissue interface, and whether surgeons can enhance the bond between mesh and tissue.Material and Methods: This study assessed the strength of the mesh-tissue interface by dynamic loads. A self-built bench test delivered dynamic impacts. The test simulated coughing. Porcine and bovine tissue were used for the bench test. Tissue quality, mesh adhesiveness, and fixation intensity influenced the retention power. The influences were condensed in a formula to assess the durability of the repair. The formula was applied to clinical work. The relative strength of reconstruction was related to the individual human abdominal wall. From computerized tomography at rest and during Valsalva's Maneuver, the tissue quality of the individual patient was determined before surgery.Results: The results showed that biomechanical parameters observed in porcine, bovine, and human tissue were in the same range. Tissues failed in distinct patterns. Sutures slackened or burst at vulnerable points. Both the load duration and the peak load increased destruction. Stress concentrations elevated failure rates. Regional areas of force contortions increased stress concentrations. Hernia repair improved strain levels. Measures for improvement included the closure of the defect, use of higher dynamic intermittent strain (DIS) class meshes, increased mesh overlap, and additional fixation. Surgeons chose the safety margin of the reconstruction as desired.Conclusion: The tissue quality has now been introduced into the concept of a critical and a gained resistance toward pressure-related impacts. A durable hernia repair could be designed from available coefficients. Using biomechanical principles, surgeons could minimize pain levels. Mesh-related complications such as hernia recurrence can potentially be avoided in incisional hernia repair.
Ubiquitination-Related Molecular Subtypes and a Novel Prognostic Index for Bladder Cancer Patients
Authors: Cai Hai , Chen Hang , Huang Qi , Zhu Jun-Ming , Ke Zhi-Bin , Lin Yun-Zhi , Zheng Qing-Shui , Wei Yong , Xu Ning , Xue Xue-Yi 
Published: October 2021

Objective: To develop and validate ubiquitination-related molecular subtypes and a novel prognostic index using ubiquitination-related genes (URGs) for patients with bladder cancer (BCa).Materials and Methods: We downloaded the clinical data and transcriptome data of BCa from TCGA and GEO database. Consensus clustering analysis was conducted to identify ubiquitination-related molecular subtypes for BCa. Besides, we performed univariate and multivariate Cox regression analysis to develop a novel prognostic URGs-related index for BCa. We conducted internal and external verification in TCGA cohort and GEO cohort, respectively. Furthermore, the associations of ubiquitination-related molecular subtypes and prognostic index with tumor immune environment were also investigated.Results: A total of four ubiquitination-related molecular subtypes of BCa were finally identified. These four molecular subtypes had significantly different clinical characteristics, prognosis, PD-L1 expression level and tumor microenvironment. Besides, we developed a novel prognostic index using six URGs (including HLA-A, TMEM129, UBE2D1, UBE2N, UBE2T and USP5). The difference in OS between high and low-risk group was statistically significant in training cohort, testing cohort, and validating cohort. The area under ROC curve (AUC) for OS prediction was 0.736, 0.723, and 0.683 in training cohort, testing cohort, and validating cohort, respectively. Multivariate survival analysis showed that this index was an independent predictor for OS. This prognostic index was especially suitable for subtype 1 and 3, older, male, high grade, AJCC stage III-IV, stage N0, stage T3-4 BCa patients.Conclusions: This study identified a total of four ubiquitination-related molecular subtypes with significantly different tumor microenvironment, prognosis, clinical characteristics and PD-L1 expression level. Besides, a novel ubiquitination-related prognostic index for BCa patients was developed and successfully verified, which performed well in predicting prognosis of BCa.
Peran Keadilan Prosedural dan Identitas Sosial Dalam Meningkatkan Efektivitas Penerapan E-Tilang Di Jakarta (Analisis Kebijakan)
Authors: Faturohman Ginanjar Maulana , Noor Mirra 
Published: October 2021

Some of the violations committed by the driver can lead to several things, which it is counter productive. According to Law No. 2 of 2009 on LLAJ (traffic and road transport) of Article 260 and Article 262 are authorized to take action against violations of traffic is the Indonesian National Police (Polri) and the Civil Servant Investigators. This study aims to assess specifically mengwnai research practice in the application of e-Ticketing system in PMJ scientifically to seek regulatory system is performed by the actors in the implementation of policies and policy arguments or opinions that develop in people who have an impact on the policy of the e-Ticketing. In this study using the method of policy analysis. Policy analysis is a social study which arranges its application in a systematic manner. There are two policies on the implementation of e-Ticketing, namely education and policy. In education there are three criteria, namely: Improving the quality of police officers, forming the image of the police, and educate the public, to inculcate a good identity and obey the law. As for policy namely a rule and punishment from police officers for extortionists or other offenders.
APPLICATION OF CONTENT ANALYSIS METHOD IN PEDAGOGICAL RESEARCH
Authors: Antonova O. , Andriichuk T. , Antonov O. 
Published: October 2021

The article presents the possibilities of applying the method of content analysis in pedagogical research carried out by future teachers. The authors emphasize the importance of preparing future teachers of geography for the organization and implementation of scientific and pedagogical research in professional activities. It is noted that research activities of students are a natural continuation and deepening of the educational process by studying specific topics and problems using a system of methods of pedagogical research, which contributes to the development of scientific and pedagogical thinking, the need for intellectual development, self-development and self-education.
It is stated that content analysis is an important tool of scientific research, which provides a step-by-step procedure for studying the basic category (concept, pedagogical phenomenon) in the system of psychological and pedagogical sciences. The essence of this method is to consistently and systematically record the units of the studied content (certain meaningful concepts), identify the frequency of their use, as well as to trace the relationship with the content of the entire document and group them for different purposes within a conceptual scheme or theory, in particular to study their specifics.
The step-by-step procedure of content analysis in the process of studying the essence of pedagogical concepts is determined. Different approaches to the application of content analysis are presented on the example of such categories as "talent", "strategic competence", "practice-oriented learning". The prospects and capabilities of the method under study in the field of construction of definitions of the analyzed concepts are illustrated.
It is concluded that content analysis in pedagogical research is an up-to-date and relevant method, which provides a powerful toolset for working with the conceptual apparatus of pedagogy, and contributes to the development of theoretical thinking of future teachers.
Efektifitas Konsumsi Madu Terhadap Peningkatan Berat Badan Ibu Hamil KEK
Authors: Susanti Dewi , Harmiyati Harmiyati 
Published: October 2021

LATAR BELAKANG: Status gizi ibu hamil sangat berpengaruh terhadap perkembangan janin dikandungnya. Ibu hamil dengan status gizi kurang beresiko mengalami komplikasi seperti anemia, perdarahan, berat badan tidak bertambah secara normal selama kehamilan dan penyakit infeksi (Devgun p, 2014). Khasiat madu sebagai suplemen untuk meningkatkan berat badan memberikan hasil yang positif, dimana ditemukan peningkatan berat badan yang signifikan pada anak-anak yang diberikan suplementasi madu yang dikombinasikan dengan temulawak (Yasin 2009).TUJUAN: mengetahui efektifitas konsumsi madu terhadap peningkatan status gizi ibu hamil KEKMETODE: Penelitian ini merupakan penelitian kuantitatif dengan menggunakan quasi-experimental design. Sampel penelitian berjumlah 32 orang ya g terdiri dari dua kelompok (control dan perlakuan)HASIL PENELITIAN: uji t test menunjukkan nilai p value untuk berat badan adalah 0,016 < 0,05 yang artinya ada pengaruh konsumsi madu terhadap berat badan ibu hamil KEK. SIMPULAN: ibu hamil yang mengkonsumsi madu memiliki pertambahan berat badan yang lebih baik disanding ibu hamil KEKyang tidak mengkonsumsi madu. Kata kunci: madu, berat badan, ibu hamil, KEK
Faktor – faktor yang Berhubungan dengan Kejadian Hipertensi Pada Akseptor KB Suntik
Authors: Widyaningsih Ari , Isfaizah Isfaizah 
Published: October 2021

Salah satu penyakit tidak menular yang banyak ditemukan pada masyarakat saat ini salah satunya adalah hipertensi yang diawali pre-hipertensi. World Health Organization (WHO) mencatat pada tahun 2012 sedikitnya 839 juta kasus hipertensi, diperkirakan menjadi 1,15 milyar pada tahun 2025 atau sekitar 29% dari total penduduk dunia, dimana penderitanya lebih banyak pada wanita (30%) dibanding pria (29%). Beberapa faktor risiko lain juga berkontribusi terhadap kenaikan tekanan darah pada wanita, diantaranya riwayat hipertensi, karakteristik seseorang (usia, jenis kelamin, ras), gaya hidup yang di dalamnya termasuk pola konsumsi lemak dan garam tinggi, makan secara berlebihan hingga mengakibatkan obesitas, kebiasaan merokok dan minum alkohol, kurang konsumsi sayuran dan buah, aktivitas fisik, pekerjaan, kualitas tidur, konsumsi kopi, stress, penggunaan alat kontrasepsi hormonal, status gizi dan obesitas sentral. Perubahan tekanan darah tinggi dapat terjadi pada 5% pemakaian kontrasepsi hormonal. Tekanan darah akan meningkat secara bertahap dan tidak akan menetap. Wanita yang memakai kontrasepsi selama 5 tahun atau lebih, frekuensi perubahan tekanan darah tinggi meningkat 2 sampai 3 kali dari pada tidak memakai alat kontrasepsi hormonal. Resiko terjadinya tekanan darah tinggi akan meningkat dengan bertambahnya umur, lama pemakaian kontrasepsi dan bertambahnya berat badan. Berdasarkan uraian di atas, peneliti tertarik melakukkan penelitian tentang. Faktor – faktor yang Berhubungan dengan Kejadian Hipertensi pada Akseptor KB Suntik. Penelitian ini merupakan analitik korelasi dengan pendekatan cross-sectional study dengan teknik pengambilan sampel accidental sampling dan uji chi square pada analisa datanya.
Uji Media Edukasi Tentang Pola Konsumsi Tablet Fe Untuk Mencegah Kejadian Resiko Tinggi Anemia Ibu Hamil
Authors: Octasila Restu , Nofita Reni , Dariyani Siti 
Published: October 2021

Background Pregnancy is a special condition for a woman as a prospective mother, because during pregnancy there will be many changes both physical, social and mental changes. During pregnancy there can also be things that cause a high-risk pregnancy especially those associated with anemia. This ignorance is one of the reasons for the lack of supporting media information related to the practice of how to consume FE tablets correctly. This study generally aims to analyze the level of understanding of mothers about how to consume FE tablets and compile an effective video information media for pregnant women about the practice of FE Tablet consumption patterns, so that it can effectively improve mothers' understanding of FE tablet consumption patterns practices that can meet FE's needs to you during pregnancy. In line with the objectives to be achieved in this study, this research uses the action research method. This method was chosen because in the first phase, research will be carried out on the condition and level of understanding of pregnant women regarding the practice of correct consumption patterns of FE tablets. Furthermore, in the second phase, an implementation / action will be carried out to implement and test the application and effectiveness of the use of information media in the form of video provided in Puskesmas Cisoka Kabupaten Tangerang. Research TKT at level 3. Results Increased knowledge of pregnant women before being given health education 42 to 65. Increased knowledge of pregnant women before being given video-based educational media 43 to 76. The targeted output in this study is to produce a video-based educational media that will increasing the percentage of regular consumption of Fe tablets in pregnant women can be accessed through in https://www.youtube.com/watch?v=MIFi0y4KjCc The conclusion in this study is the analys of media needed to increase the knowledge of pregnant women about the consumption patterns of Fe tablets that are adequate to reduce the risk of anemia in pregnant women. Significant increase in knowledge of pregnant women (P. value 0.001). The advice given to the providers of care (Midwives) is to use video-based educational media as an alternative media for health education.
Literature Review Pengaruh Asam Folat Pada Kadar Hemoglobin Untuk Wanita Prakonsepsi Dengan Anemia
Authors: Putri Alifia Akhmad  , Listiyaningsih Moneca Diah 
Published: October 2021

Folic acid is important in the process of formation and maturation of erythrocytes, so that folic acid deficiency can manifest in anemia. Anemia is defined by hemoglobin levels in preconception women <12.0 g/dl, one of which is due to the lack of erythrocyte. Globally, the prevalence of anemia in women not pregnant (childbearing age) is 1.1%, and affects 19 million women not pregnant. Prevention of anemia in women of childbearing age can improve the degree of health of pregnant women, which ultimately contributes to a decrease in maternal and perinatal death. So that in preconception care is recommended anemia prevention measures in the form of nutritional interventions, one of which is recommended to prevent folic acid deficiency. The purpose of the study was to find out the influence of folic acid on hemoglobin levels of preconception women with anemia. literature review study, study 5 articles that meet inclusion and exclusion criteria. Search through Google Scholar, Garuda, and Pubmed, keywords that iron folic acid, folic acid, and anemia in preconception. from 5 articles examined there was an influence of folic acid on hemoglobin levels in preconception women. hemoglobin levels in preconception women are influenced by the adequacy of folic acid. So folic acid deficiency has an effect on the incidence of anemia in preconception women
ABSTRAK
Asam folat penting dalam proses pembentukan dan pematangan eritrosit, sehingga defisiensi asam folat bisa bermanifestasi pada anemia. Anemia didefinisikan dengan kadar hemoglobin pada wanita prakonsepsi <12,0 g/dl yang salah satunya dikarenakan kurangnya jumlah eritrosit. Secara global, prevalensi anemia pada wanita tidak hamil (usia subur) yaitu 1,1%, dan mempengaruhi 19 juta wanita tidak hamil. Pencegahan anemia pada wanita usia subur dapat meningkatkan derajat kesehatan wanita hamil, yang pada akhirnya berkontribusi pada penurunan kematian ibu dan perinatal. Sehingga dalam pelayanan kesehatan prakonsepsi (preconception care) dianjurkan tindakan pencegahan anemia berupa intervensi gizi yang salah satunya dianjurkan untuk mencegah defisiensi asam folat. Tujuan penelitian untuk mengetahui pengaruh asam folat pada kadar hemoglobin wanita prakonsepsi dengan anemia. Studi literature review, menelaah 5 artikel yang memenuhi kriteria inklusi dan eksklusi. Pencarian melalui Google Scholar, Garuda, dan Pubmed, kata kunci yang iron folic acid, asam folat, dan anemia in preconception. Dari 5 artikel yang ditelaah didapatkan adanya pengaruh asam folat terhadap kadar hemoglobin pada wanita prakonsepsi. Kadar hemoglobin pada wanita prakonsepsi salah satunya dipengaruhi oleh tingkat kecukupan asam folat. Sehingga defisiensi asam folat berpengaruh pada kejadian anemia pada wanita prakonsepsi.