bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamic capabilities in the “new normal”: a study of organizational flexibility, integration and agility in the Peruvian coffee supply chain
Authors: Ramos Edgar , Patrucco Andrea S. , Chavez Melissa 
Published: August 2021

Purpose
Considering the unprecedented supply chain disruptions due to the COVID-19 pandemic, especially in the agri-food sector, the possession of dynamic capabilities (DCs) – particularly, the need for higher agility – seems to be the key to survival in highly uncertain environments. This study aims to use the dynamic capability view (DCV) theory to analyze how three key supply chain capabilities – organizational flexibility, integration and agility – should be combined to obtain the desired supply chain performance.

Design/methodology/approach
The authors designed a conceptual model in which the relationships between these three key capabilities and supply chain performance were hypothesized. The model was first tested through partial least square regression using survey data collected from 98 members of the Peruvian coffee supply chain. A fuzzy-set qualitative comparative analysis (fsQCA) was conducted to uncover how DCs could be combined in successful supply chain configurations.

Findings
The authors show that organizational flexibility is a driver of higher agility in agri-food supply chains, together with external and internal supply chain integration, that have a direct impact on agility, which positively affects supply chain performance. Higher levels of supply chain agility are necessary but insufficient to guarantee high performance, as sufficiency is reached when both integration (internal and/or external) and agility are present.

Originality/value
This study represents a pioneering attempt to apply the DCV theory to agri-food supply chains – characterized by many sources of uncertainty. All the DCs are included within the same model and the joint use of PLS regression and fsQCA provides evidence about the relationships between DCs and how they can empower agri-food supply to obtain the desired performance.
Travel time forecasting on a freeway corridor: a dynamic information fusion model based on the random forests approach
Authors: Qiu Bo , Fan Wei 
Published: August 2021

Purpose
Metropolitan areas suffer from frequent road traffic congestion not only during peak hours but also during off-peak periods. Different machine learning methods have been used in travel time prediction, however, such machine learning methods practically face the problem of overfitting. Tree-based ensembles have been applied in various prediction fields, and such approaches usually produce high prediction accuracy by aggregating and averaging individual decision trees. The inherent advantages of these approaches not only get better prediction results but also have a good bias-variance trade-off which can help to avoid overfitting. However, the reality is that the application of tree-based integration algorithms in traffic prediction is still limited. This study aims to improve the accuracy and interpretability of the models by using random forest (RF) to analyze and model the travel time on freeways.

Design/methodology/approach
As the traffic conditions often greatly change, the prediction results are often unsatisfactory. To improve the accuracy of short-term travel time prediction in the freeway network, a practically feasible and computationally efficient RF prediction method for real-world freeways by using probe traffic data was generated. In addition, the variables’ relative importance was ranked, which provides an investigation platform to gain a better understanding of how different contributing factors might affect travel time on freeways.

Findings
The parameters of the RF model were estimated by using the training sample set. After the parameter tuning process was completed, the proposed RF model was developed. The features’ relative importance showed that the variables (travel time 15 min before) and time of day (TOD) contribute the most to the predicted travel time result. The model performance was also evaluated and compared against the extreme gradient boosting method and the results indicated that the RF always produces more accurate travel time predictions.

Originality/value
This research developed an RF method to predict the freeway travel time by using the probe vehicle-based traffic data and weather data. Detailed information about the input variables and data pre-processing were presented. To measure the effectiveness of proposed travel time prediction algorithms, the mean absolute percentage errors were computed for different observation segments combined with different prediction horizons ranging from 15 to 60 min.
Fantastic teams and where to find them: understanding team processes in space and analog environments through the IMOI framework
Authors: Käosaar Andres , Marques-Quinteiro Pedro , Burke Shawn 
Published: August 2021

Purpose
This paper aims to propose a model of teamwork effectiveness in space and analog environments (SAE).

Design/methodology/approach
A systematic literature review was conducted to examine the state-of-the-art of teamwork literature in SAE. A total of 37 research papers were reviewed and the results were organized according to the input-mediator-output-input (IMOI) framework.

Findings
Based on 37 empirical research papers, the findings suggest that the teams working in SAE are challenged with contextual (e.g. time, isolation and confinement), collective (e.g. autonomy, culture) and individual (e.g. personality) attributes. These are inputs to team processes (e.g. interpersonal processes; communication) and emergent states (e.g. climate; emotions), which mediate team (e.g. performance; cohesion) and individual (e.g. psychological well-being) outputs.

Research limitations/implications
Given the review nature of the manuscript, the final proposed model depicting empirical findings lacks validation evidence when considered in its entirety, although pieces have been validated. Additionally, the focus only on papers that included team-level empirical SAE research (excluding individual-level studies), undoubtedly contributed to a smaller number of papers extracted.

Originality/value
This paper integrates empirical findings regarding the factors impacting team performance in SAE into a proven framework (IMOI). This integration can provide a common baseline, using a widely accepted methodology and framework, that serves to guide future research, identify gaps and guide practice.
Predictive modeling of service discontinuation in transitional age youth with recent behavioral health service use
Authors: Bory Christopher , Schmutte Timothy , Davidson Larry , Plant Robert 
Published: August 2021

AbstractObjectiveTo develop and test predictive models of discontinuation of behavioral health service use within 12 months in transitional age youth with recent behavioral health service use.Data sourcesAdministrative claims for Medicaid beneficiaries aged 15–26 years in Connecticut.Study designWe compared the performance of a decision tree, random forest, and gradient boosting machine learning algorithms to logistic regression in predicting service discontinuation within 12 months among beneficiaries using behavioral health services.Data extractionWe identified 33,532 transitional age youth with ≥1 claim for a primary behavioral health diagnosis in 2016 and Medicaid enrollment of ≥11 months in 2016 and ≥11 months in 2017.Principal findingsClassification accuracy for identifying youth who discontinued behavioral health service use was highest for gradient boosting (80%, AUC = 0.86), decision tree (79%, AUC = 0.84), and random forest (79%, AUC = 0.86), as compared with logistic regression (71%, AUC = 0.71).ConclusionsPredictive models based on Medicaid claims can assist in identifying transitional age youth who are at risk of discontinuing from behavioral health care within 12 months, thus allowing for proactive assessment and outreach to promote continuity of care for younger persons who have behavioral health needs.
Do Managers Issue More Voluntary Disclosure When GAAP Limits Their Reporting Discretion in Financial Statements?
Authors: HRIBAR PAUL , MERGENTHALER RICHARD , ROESCHLEY AARON , YOUNG SPENCER , ZHAO CHRIS X. 
Published: August 2021

ABSTRACTWe examine whether managers provide more voluntary disclosure when GAAP limits their reporting discretion in financial statements. We find managers are more likely to disclose non‐GAAP earnings, issue more management forecasts, and provide longer yet more readable management discussion and analysis (MD&A) disclosures when GAAP limits their discretion. These effects are stronger when there is greater demand for information and better monitoring. In contrast, these effects are weaker when managers have incentives to manage earnings. Difference‐in‐differences analyses around standard changes provide further evidence that managers make more non‐GAAP adjustments and are more likely to discuss the standard and its underlying transaction in the MD&A when a new standard limits their discretion more than its predecessor. Collectively, our results suggest managers use voluntary disclosure channels to convey information when GAAP limits their ability to recognize such information in financial statements.
Rapid formation of mature microbialites in Lake Alchichica, Mexico
Authors: Iniesto Miguel , Moreira David , Benzerara Karim , Muller Elodie , Bertolino Paola , Tavera Rosaluz , López‐García Purificación 
Published: August 2021

SummaryMicrobialites are emblematic sedimentary rocks formed by phylogenetically and metabolically complex microbial communities thriving under specific physicochemical conditions. Most microbialites are photosynthesis‐based ecosystems frequently formed by carbonates, thereby capturing inorganic carbon in the form of both, organic matter and mineral precipitates. However, little is known about the amount of sequestered carbon and the kinetics of the process, that is, microbialite growth rate. To assess microbialite growth rate and the influence of substrates on carbonate formation in Alchichica, an alkaline crater lake harbouring well‐developed carbonate microbialites, we incubated in situ sterilized Nylon mesh, hydromagnesite and aragonite crystals, and bleached‐coral aragonite for 2 years. We observed the rapid formation of nascent hydromagnesite and aragonite‐containing microbialites on Nylon mesh, with an average growth rate of ~0.6 (and up to 1) mm year−1. By contrast, only thin (< 0.2 mm) biofilms developed on exposed hydromagnesite and aragonite crystals and bleached‐coral aragonite, suggesting decoupled microbial colonization and biomineralization and/or potential interference of those mineral surfaces with new carbonate nucleation. Microbial communities associated with 2‐year‐old microbialites and biofilms were fully comparable to mature communities populating Lake Alchichica indigenous microbialites.
A lesson in clinicopathological correlation: Plaque‐like myofibroblastic tumour presenting as a pruritic plaque in childhood
Authors: Yiu Daniel , Yau Benny , Abdul‐Wahab Alya , Chong Heung 
Published: August 2021

AbstractPlaque‐like myofibroblastic tumour (PLMT) is a rare skin condition which presents in childhood and infancy as a nodular fibrous plaque. Including our case, there are currently only 14 cases reported in the literature. Although it represents a well‐defined clinicopathological diagnosis, there is significant under‐reporting of this condition secondary to under‐recognition and potential misdiagnosis as dermatofibroma.
Exploring mechanisms of a web‐based values‐tailored childhood vaccine promotion intervention trial: Effects on parental vaccination values, attitudes, and intentions
Authors: Kwan Bethany M. , Pyrzanowski Jennifer , Sevick Carter , Wagner Nicole M. , Resnicow Kenneth , Glanz Jason M. , Dempsey Amanda F. 
Published: August 2021

AbstractA recent childhood vaccine promotion intervention trial showed no effects on vaccination outcomes relative to usual care. The purpose of this paper was to test assumptions and theory‐based relationships underlying hypothesised mechanisms for two vaccine promotion educational websites (one tailored to parental values, beliefs, and intentions; one untailored) compared with usual care. This is a secondary analysis of a three‐arm randomized controlled trial. Parental vaccine values, hesitancy, attitudes, and intention to vaccinate surveys were administered at baseline (≤2 months) and at 4–6 and 10–12 months of age. Vaccination was assessed using electronic health records. Analyses included random coefficient models and risk differences with exact confidence limits. Parental vaccine values were mostly stable over time. Vaccine attitudes were generally positive, with no differences among study arms. Both tailored and untailored website arms showed similar increases in intention to vaccinate more than usual care. Positive changes in intentions were associated with lower rates of late vaccination. Although attitudes and intentions predicted vaccination behavior and the intervention increased intention to vaccinate all on time, the web‐based education and values‐tailored messaging approaches were not effective at increasing vaccination rates. Intentions are necessary but insufficient targets for vaccine promotion interventions.
In vitro assessments predict that CYP3A4 contributes to a greater extent than CYP3A5 to prednisolone clearance
Authors: Skauby Ragnhild Heier , Bergan Stein , Andersen Anders M. , Vethe Nils Tore , Christensen Hege 
Published: August 2021

AbstractBecause several steroid hormones are metabolized to their respective 6β‐hydroxy forms by CYP3A4 and CYP3A5, these isoenzymes have been assumed to metabolize the immunosuppressive drug prednisolone, with conflicting results in the literature with respect to their relative importance. A direct study of the metabolism of prednisolone by microsomal CYP3A4 and CYP3A5 is missing. The aim of this in vitro study was to investigate the relative importance of recombinant CYP3A4 and recombinant CYP3A5 in the metabolism of prednisolone and to compare the extent of formation of 6β‐OH‐prednisolone by the two enzymes. Through in vitro incubations using rCYP3A4 and rCYP3A5 enzymes, intrinsic clearance (CLint) of prednisolone was determined by the substrate depletion approach. Formation of the metabolite 6β‐OH‐prednisolone by rCYP3A4 and rCYP3A5, respectively, was compared. Prednisolone concentrations were measured, and its metabolite 6β‐OH‐prednisolone was identified using a HPLC‐MS/MS in‐house method. CLint for prednisolone by rCYP3A5 was less than 26% relative to rCYP3A4. Formation of 6β‐OH‐prednisolone by rCYP3A5 was less than 11% relative to rCYP3A4. The study indicates that 6β‐hydroxylation of prednisolone assessed in vitro in recombinant CYP enzymes depends on rCYP3A4 rather than rCYP3A5 and that CYP3A5 may be responsible for the formation of other prednisolone metabolite(s) in addition to 6β‐OH‐prednisolone.
Syn‐rift hydrothermal circulation in the Mesozoic carbonates of the western Adriatic continental palaeomargin (Western Southalpine Domain, NW Italy)
Authors: Barale L. , Bertok C. , d’Atri A. , Mantovani A. , Martire L. , Agostini S. , Bernasconi S. M. , Gerdes A. , Ferrando S. 
Published: August 2021

AbstractEvidence of hydrothermal activity is reported for the Mesozoic pre‐ and syn‐rift successions of the western Adriatic palaeomargin of the Alpine Tethys, preserved in the Western Southalpine Domain (NW Italy). The products of hydrothermal processes are represented by vein and breccia cements, as well as dolomitization and silicification of the host rocks. In the eastern part of the study area, interpreted as part of the necking zone of the continental margin, Middle Triassic dolostones and Lower Jurassic sediments are crossed by veins and hydrofracturing breccias cemented by saddle dolomite. The precipitation of dolomite cements occurred within the stratigraphic succession close to the sediment–water interface. Despite the shallow burial depth, fluid inclusion microthermometry and clumped isotopes show that hydrothermal fluids were relatively hot (80–150°C). In the western part of the study area, interpreted as part of the hyperextended distal zone, a polyphase history of host‐rock fracturing is recorded, with at least two generations of veins cemented by calcite, dolomite and quartz. Vein opening and cementation occurred at shallow burial depth around the time of deposition of the syn‐rift clastic succession. Fluid inclusion microthermometry on both quartz and dolomite cements indicates a fluid temperature of 90–130°C, again pointing to hydrothermal fluids. Both in Fenera‐Sostegno and Montalto Dora areas, O, C and Sr isotope values, coupled with fluid inclusion and clumped isotope data, indicate that hydrothermal fluids derived from seawater interacted with crustal rocks during hydrothermal circulation. Stratigraphic and petrographic evidence, and U–Pb dating of dolomitized clasts within syn‐rift sediments, document that hydrothermal fluids circulated through sediments from the latest Triassic to the Toarcian, corresponding to the entire syn‐rift evolution of the western portion of the Adriatic palaeomargin. The documented hydrothermal processes are temporally correlated with regional‐scale thermal events that took place in the same time interval at deeper crustal levels.
Calcitonin gene‐related peptide induces the histone H3 lysine 9 acetylation in astrocytes associated with neuroinflammation in rats with neuropathic pain
Authors: Sun Chenyan , An Qi , Li Ruidi , Chen Shuhui , Gu Xinpei , An Shuhong , Wang Zhaojin 
Published: August 2021

AbstractAimsCalcitonin gene‐related peptide (CGRP) as a regulator of astrocyte activation may facilitate spinal nociceptive processing. Histone H3 lysine 9 acetylation (H3K9ac) is considered an important regulator of cytokine and chemokine gene expression after peripheral nerve injury. In this study, we explored the relationship between CGRP and H3K9ac in the activation of astrocytes, and elucidated the underlying mechanisms in the pathogenesis of chronic neuropathic pain.MethodsAstroglial cells (C6) were treated with CGRP and differentially enrichments of H3K9ac on gene promoters were examined using ChIP‐seq. A chronic constriction injury (CCI) rat model was used to evaluate the role of CGRP on astrocyte activation and H3K9ac signaling in CCI‐induced neuropathic pain. Specific inhibitors were employed to delineate the involved signaling.ResultsIntrathecal injection of CGRP and CCI increased the number of astrocytes displaying H3K9ac in the spinal dorsal horn of rats. Treatment of CGRP was able to up‐regulate H3K9ac and glial fibrillary acidic protein (GFAP) expression in astroglial cells. ChIP‐seq data indicated that CGRP significantly altered H3K9ac enrichments on gene promoters in astroglial cells following CGRP treatment, including 151 gaining H3K9ac and 111 losing this mark, which mostly enriched in proliferation, autophagy, and macrophage chemotaxis processes. qRT‐PCR verified expressions of representative candidate genes (ATG12, ATG4C, CX3CR1, MMP28, MTMR14, HMOX1, RET) and RTCA verified astrocyte proliferation. Additionally, CGRP treatment increased the expression of H3K9ac, CX3CR1, and IL‐1β in the spinal dorsal horn. CGRP antagonist and HAT inhibitor attenuated mechanical and thermal hyperalgesia in CCI rats. Such analgesic effects were concurrently associated with the reduced levels of H3K9ac, CX3CR1, and IL‐1β in the spinal dorsal horn of CCI rats.ConclusionOur findings highly indicate that CGRP is associated with the development of neuropathic pain through astrocytes‐mediated neuroinflammatory responses via H3K9ac in spinal dorsa horn following nerve injury.This study found that CGRP act on their astrocytic receptors and lead to H3K9 acetylation (H3K9ac), which are mainly associated with proliferation‐, autophagy‐, and inflammation‐related gene expression. The number of astrocytes with H3K9ac expression is increased after nerve injury. Inhibition of CGRP attenuates the development of neuropathic pain, which was accompanied by the suppression of H3K9ac, CX3CR1, and IL‐1β expression in CCI rats.
Plus compliqué qu'il n'y paraît: l'OIT et le champ d'application personnel des normes internationales du travail
Authors: DE STEFANO Valerio 
Published: August 2021

RésuméL'analyse porte sur le champ d'application personnel des normes internationales du travail de l'OIT. Relevant que celles‐ci ne proposent pas de définition universelle des termes «salarié» et «relation de travail», l'auteur affirme qu'il faut déterminer ce champ d'application au cas par cas, en s'appuyant sur les comptes rendus des travaux préparatoires et sur les avis des organes de contrôle de l'Organisation. Il illustre son propos en analysant de façon approfondie l'interprétation que ces instances ont faite des conventions fondamentales de l'OIT, tout en commentant les discussions que la question du champ d'application personnel a suscitées récemment au sein de l'Organisation.
Les préférences des femmes en matière de temps de travail: pour en finir avec quelques idées reçues sur le sous‐emploi, la centralité du travail et la conciliation entre vie professionnelle et vie privée
Authors: LAMOLLA Laura , FOLGUERA‐I‐BELLMUNT Conxita , FERNÁNDEZ‐I‐MARÍN Xavier 
Published: August 2021

RésuméL'étude porte sur les préférences en matière de temps de travail de femmes occupées vingt heures par semaine, selon des horaires fixes, dans une entreprise manufacturière. Sur la base d'une analyse quantitative et qualitative, les auteurs définissent plusieurs profils types, en fonction de ces préférences et des motivations sous‐jacentes. Leurs résultats permettent de nuancer les conclusions d'études précédentes: 1) toutes les travailleuses interrogées ne peuvent pas ětre considérées comme étant en sous‐emploi; 2) měme à temps partiel, le travail peut ětre central et avoir du sens; 3) malgré la faiblesse du salaire, le temps libéré par le temps partiel n'est pas toujours destiné aux obligations familiales.
«Eslabones perdidos» en el debate sobre el crecimiento inclusivo: distribución funcional de la renta e instituciones laborales
Authors: ÁLVAREZ Ignacio , KEUNE Maarten , CRUCES Jesús , UXÓ Jorge 
Published: August 2021

ResumenLos autores examinan en qué medida las propuestas de «crecimiento inclusivo» de la UE, la OCDE y el FMI responden a sus propios objetivos. Se identifican dos «eslabones perdidos» en estas propuestas: la distribución funcional de la renta y las instituciones laborales. Con datos de panel de 42 economías desarrolladas para 1990‐2018, los autores observan cómo la distribución funcional de la renta condiciona la distribución personal, y cómo la cobertura de la negociación colectiva aumenta la participación de los salarios en el PIB y reduce la desigualdad de ingresos. Estos dos «eslabones» deben pues integrarse en las propuestas de «crecimiento inclusivo».