bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fiber intake and health in people with chronic kidney disease
Authors: Su Guobin , Qin Xindong , Yang Changyuan , Sabatino Alice , Kelly Jaimon T , Avesani Carla Maria , Carrero Juan Jesus 
Published: September 2021

Abstract
Emerging evidence suggests that diet, particularly one that is rich in dietary fiber, may prevent the progression of chronic kidney disease (CKD) and its associated complications in people with established CKD. This narrative review summarizes the current evidence and discusses the opportunities for increasing fiber intake in people with CKD to improve health and reduce disease complications. A higher consumption of fiber exerts multiple health benefits, such as increasing stool output, promoting the growth of beneficial microbiota, improving the gut barrier and decreasing inflammation, as well decreasing uremic toxin production. Despite this, the majority of people with CKD consume less than the recommended dietary fiber intake, which may be due in part to the competing dietary potassium concern. Based on existing evidence, we see benefits from adopting a higher intake of fiber-rich food, and recommend cooperation with the dietitian to ensure an adequate diet plan. We also identify knowledge gaps for future research and suggest means to improve patient adherence to a high-fiber diet.
Computational Model for Prediction of Malignant Mesothelioma Diagnosis
Authors: Gupta Surbhi , Gupta Manoj Kumar 
Published: September 2021

Abstract
Mesothelioma is an aggressive lung cancer, harms the linings of the lungs. It is one of the deadliest cancers diagnosed in those exposed to fibrous silicate minerals (asbestos). Millions of people face severe consequences as they are diagnosed at late stages. This study presents a comparison of several machine learning approaches with distinct feature sets and addresses the issue of class imbalance. The dataset used in this study is available publicly on the University of California Irvine (UCI) machine learning repository. This study used the resampling technique, synthetic minority oversampling technique (SMOTE), and adaptive synthetic sampling (ADASYN) to handle the class imbalance. Most of the machine learning strategies performed well with the resampling technique. The best accuracy using the resampling strategy was achieved by artificial neural networks (ANN). The highest accuracy was recorded on the feature set selected by principal component analysis (PCA) is 96%. Overall, ensemble techniques performed well. The proposed stacking-based classifier achieved the highest accuracy (89%) on data balanced using SMOTE and ADASYN.
Single-cell RNA sequencing profiling of mouse endothelial cells in response to pulmonary arterial hypertension
Authors: Rodor Julie , Chen Shiau Haln , Scanlon Jessica P , Monteiro João P , Caudrillier Axelle , Sweta Sweta , Stewart Katherine Ross , Shmakova Alena , Dobie Ross , Henderson Beth E P , Stewart Kevin , Hadoke Patrick W F , Southwood Mark , Moore Stephen D , Upton Paul D , Morrell Nick W , Li Ziwen , Chan Stephen Y , Handen Adam , Lafyatis Robert , de Rooij Laura P M H , Henderson Neil C , Carmeliet Peter , Spiroski Ana Mishel , Brittan Mairi , Baker Andrew H 
Published: September 2021

AbstractAimsEndothelial cell (EC) dysfunction drives the initiation and pathogenesis of pulmonary arterial hypertension (PAH). We aimed to characterize EC dynamics in PAH at single-cell resolution.Methods and resultsWe carried out single-cell RNA sequencing (scRNA-seq) of lung ECs isolated from an EC lineage-tracing mouse model in Control and SU5416/hypoxia-induced PAH conditions. EC populations corresponding to distinct lung vessel types, including two discrete capillary populations, were identified in both Control and PAH mice. Differential gene expression analysis revealed global PAH-induced EC changes that were confirmed by bulk RNA-seq. This included upregulation of the major histocompatibility complex class II pathway, supporting a role for ECs in the inflammatory response in PAH. We also identified a PAH response specific to the second capillary EC population including upregulation of genes involved in cell death, cell motility, and angiogenesis. Interestingly, four genes with genetic variants associated with PAH were dysregulated in mouse ECs in PAH. To compare relevance across PAH models and species, we performed a detailed analysis of EC heterogeneity and response to PAH in rats and humans through whole-lung PAH scRNA-seq datasets, revealing that 51% of up-regulated mouse genes were also up-regulated in rat or human PAH. We identified promising new candidates to target endothelial dysfunction including CD74, the knockdown of which regulates EC proliferation and barrier integrity in vitro. Finally, with an in silico cell ordering approach, we identified zonation-dependent changes across the arteriovenous axis in mouse PAH and showed upregulation of the Serine/threonine-protein kinase Sgk1 at the junction between the macro- and microvasculature.ConclusionThis study uncovers PAH-induced EC transcriptomic changes at a high resolution, revealing novel targets for potential therapeutic candidate development.
Ant Communities and Ecosystem Services in Organic Versus Conventional Agriculture in the U.S. Corn Belt
Authors: Helms Jackson A , Smith Jamie , Clark Stephanie , Knupp Kathleen , Haddad Nick M 
Published: September 2021

Abstract
Reducing the use of synthetic fertilizers and pesticides can limit negative impacts of agriculture on insects and is a crucial step towards sustainable agriculture. In the United States, organic agriculture has the potential to reduce greenhouse gas emissions, pollutant runoff, and biodiversity loss in the Midwestern Corn Belt—an area extending over 500,000 km2 devoted to intensive production of corn Zea mays (Linnaeus 1753) (Poales: Poaceae), often in rotation with soy Glycine max (Linnaeus 1753) (Fabales: Fabaceae) or wheat Triticum aestivum (Linnaeus 1753) (Poales: Poaceae). Working in 30-yr-long landscape experiments in this region, we tested for impacts of conventional versus organic agriculture on ant communities (Hymenoptera: Formicidae) and potential ecosystem services they provide. Organic fields supported higher ant diversity and a slightly more species-rich ant assemblage than conventionally managed fields but did not otherwise differ in community composition. Despite similar community composition, organic and conventional fields differed in seasonal patterns of ant foraging activity and potential for natural pest suppression. Conventional plots experienced higher overall ant foraging activity, but with the timing skewed towards late in the growing season such that 75% of ant foraging occurred after crop harvest in a wheat year and was therefore unavailable for pest suppression. Organic fields, in contrast, experienced moderate levels of ant foraging activity throughout the growing season, with most foraging occurring during crop growth. Organic fields thus supported twice as much pest suppression potential as conventional fields. Our results highlight the importance of timing in mediating ecosystem services in croplands and emphasize the value of managing landscapes for multiple services rather than yield alone.
Viscoelastic Love numbers and long-period geophysical effects
Authors: Michel A , Boy J-P 
Published: September 2021

SUMMARY
Long term deformations strongly depend on the earth model and its rheological parameters, and in particular its viscosity. We give the general theory and the numerical scheme to compute them for any spherically non-rotating isotropic earth model with linear rheology, either elastic or viscoelastic. Although the Laplace transform (LT) is classically used to compute viscoelastic deformation, we choose here instead, to implement the integration with the Fourier transform (FT) in order to take advantage of the fast FT algorithm and avoid some of the LT mathematical difficulties. We describe the methodology to calculate deformations induced by several geophysical signals regardless of whether they are periodic or not, especially by choosing an adapted time sampling for the FT. As examples, we investigate the sensitivity of the displacements due to long period solid Earth tides, glacial isostatic adjustment and present-day ice melting, to anelastic parameters of the mantle. We find that the effects of anelasticity are important for long period deformation and relatively low values of viscosities for both Maxwell and Burgers models. We show that slight modifications in the rheological models could significantly change the amplitude of deformation but also affect the spatial and temporal pattern of the signal to a lesser extent. Especially, we highlight the importance of the mantle anelasticity in the low degrees deformation due to present-day ice melting and encourage its inclusion in future models.
Monte Carlo simulations of coupled body- and Rayleigh-wave multiple scattering in elastic media
Authors: Xu Zongbo , Margerin Ludovic , Mikesell T Dylan 
Published: September 2021

SUMMARY
Seismic coda waves are commonly used in estimation of subsurface Q values and monitoring subsurface changes. Coda waves mainly consist of multiply scattered body and surface waves. These two types of waves interact with each other in the multiple scattering process, which thus leads to a spatiotemporal evolution of the body and surface wave energies. One cannot characterize the evolution because one has not fully understood the multiple scattering of the two types of waves. Thus one commonly assumes only one type of waves exists or ignores their interaction while studying the coda waves. However, neglecting the interaction leads to an incorrect energy evolution of the two types of waves and consequently biases the Q estimation or interpretation of coda wave changes for monitoring. To better understand the interaction between these waves during multiple scattering and to model the energy evolution correctly, we propose a Monte Carlo algorithm to model the multiple scattering process. We describe the physics of the scattering for the two types of waves and derive scattering properties like cross sections for perturbations in elastic properties (e.g. density, shear modulus and Lamé parameters). Our algorithm incorporates this knowledge and thus physically models the body- and surface wave energy evolution in space and time. The energy partitioning ratios between surface and body waves provided by our algorithm match the theoretical prediction based on equipartition theory. In the equipartition state, our simulation results also match Lambert’s cosine law for body waves on the free surface. We discuss how the Rayleigh-to-body-wave scattering affects the energy partitioning ratios. Our algorithm provides a new tool to study multiple scattering and coda waves in elastic media with a free surface.
Synthetic case study: discrimination of unexploded ordnance (UXO) and non-UXO sources with varying remanent magnetization strength using magnetic data
Authors: Wigh Mark David , Hansen Thomas Mejer , Døssing Arne 
Published: September 2021

SUMMARY
We investigate if it is theoretically possible to discriminate between unexploded ordnance (UXO) and non-UXO sources by modelling the magnetic dipole moment for ferrous objects of different shapes and sizes. This is carried out by approximating the volumetric demagnetization factors of rectangular prisms, representing shapes similar to a long rod or flat steel plate. By modelling different UXO as prolate spheroids the demagnetization factors can be determined which can be compared with the magnetic response of a prism. The inversion is carried out in a probabilistic framework, where the UXO forward model and the non-UXO forward model are assigned individual prior models in terms of shape, size, orientation and remanent magnetization of the object. 95 independent realizations of the prism prior model are generated to make 95 synthetic anomalies exemplifying non-UXO objects, which are inverted for using the UXO model. It is investigated if an identical magnetic moment can be produced between the two models and how well resolved the magnetic moment is in terms of the measured anomaly. The case study is carried out in two steps where we first have little prior information of expected UXO properties and another where a UXO prior is introduced with expected values of aspect ratio and size of 24 different UXO, that are often encountered in the North Sea. With no prior information of expected UXO, discrimination is at many times implausible, unless elongated rod prism objects are considered, where the magnetic moment often can not be reproduced by a spheroid. Introducing the UXO prior we achieve a much better discrimination rate when using the list of expected UXO properties. By using the UXO prior we can account for a much higher remanent magnetization allowed in the prior, and still achieve high discrimination capabilities in comparison to a case with no UXO prior.
A scoping review of the determinants of foetal alcohol spectrum disorder in South Africa: an intersectional perspective
Authors: De Jong Michelle , George Asha , Jacobs Tanya 
Published: September 2021

Abstract
Foetal alcohol spectrum disorder (FASD) affects babies born to mothers who consume alcohol while pregnant. South Africa has the highest prevalence of FASD in the world. We review the social determinants underpinning FASD in South Africa and add critical insight from an intersectional feminist perspective. We undertook a scoping review, guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews guidelines. Drawing from EBSCOhost and PubMed, 95 articles were screened, with 21 selected for analysis. We used the intersectionality wheel to conceptualize how the social and structural determinants of FASD identified by the literature are interconnected and indicative of broader inequalities shaping the women and children affected. Key intersecting social determinants that facilitate drinking during pregnancy among marginalized populations in South Africa documented in the existing literature include social norms and knowledge around drinking and drinking during pregnancy, alcohol addiction and biological dependence, gender-based violence, inadequate access to contraception and abortion services, trauma and mental health, and moralization and stigma. Most of the studies found were quantitative. From an intersectional perspective, there was limited analysis of how the determinants identified intersect with one another in ways that exacerbate inequalities and how they relate to the broader structural and systemic factors undermining healthy pregnancies. There was also little representation of pregnant women’s own perspectives or discussion about the power dynamics involved. While social determinants are noted in the literature on FASD in South Africa, much more is needed from an intersectionality lens to understand the perspectives of affected women, their social contexts and the nature of the power relations involved. A critical stance towards the victim/active agent dichotomy that often frames women who drink during pregnancy opens up space to understand the nuances needed to support the women involved while also illustrating the contextual barriers to drinking cessation that need to be addressed through holistic approaches.
Post-release survival and prolonged sublethal effects of capture and barotrauma on deep-dwelling rockfishes (genus Sebastes): implications for fish management and conservation
Authors: Wegner Nicholas C , Portner Elan J , Nguyen Drew T , Bellquist Lyall , Nosal Andrew P , Pribyl Alena L , Stierhoff Kevin L , Fischer Paul , Franke Ken , Vetter Russell D , Hastings Philip A , Semmens Brice X , Hyde John R 
Published: September 2021

Abstract
Barotrauma—injury induced by changes in pressure—is a widespread challenge for successfully releasing fishes following capture. We used acoustic telemetry to examine the long-term post-release survival and behaviour of four rockfish species (genus Sebastes) suffering from barotrauma following capture using recreational fishing techniques. We placed particular emphasis on examining Cowcod (Sebastes levis) and Bocaccio (Sebastes paucispinis), two historically overfished species along the United States West Coast that serve as good model species representing different ecological lifestyles. We show that fish survival was species specific and that 40% of observed mortality occurred more than 48 h post release—a typical time period used in many short-term survivorship studies. Cowcod survival was correlated with fish length, sea surface temperature, and dissolved oxygen concentration at the mean depth of capture. Generalized additive mixed models of Cowcod and Bocaccio behaviour showed that surviving individuals were negatively affected by capture and barotrauma for at least 30 d post-release. Our findings demonstrate the need for extended observations to accurately quantify the mortality of fishes suffering from barotrauma and show how such data can be successfully implemented into fisheries management through engagement between managers, scientists, and the fishing community.
Using Visual Grouping to Improve Navigation of Skip Patterns in Mail Surveys: An Experiment
Authors: Powell Rebecca J , Smyth Jolene D 
Published: September 2021

AbstractSkip patterns, in which certain questions should only be answered by subsets of respondents, are particularly challenging for mail surveys because respondents must navigate them themselves with no assistance from a computer or interviewer. Incorrect navigation of skip patterns can lead to (1) errors of omission, which is when respondents fail to answer follow-up questions they should answer; (2) errors of commission, which is when respondents answer follow-up questions they should skip; or (3) filter item nonresponse, which is when respondents fail to answer the initial filter question. Using experimental data from two general population surveys of Nebraskans, this paper examines three visual design elements—common region, indentation, and subnumbering—aimed at decreasing skip errors in mail surveys. Each design element is intended to create stronger grouping and subgrouping among items within skip patterns, thus clarifying the navigational path and decreasing skip errors. We compare error rates across treatments overall and by respondent age, education, and literacy to assess whether visual cues can provide additional aid to those who might struggle with reading text cues. We find that using separate enclosures or subnumbering of the follow-up questions significantly reduces commission error rates and using indentation significantly increases omission error rates. In addition, none of the tested visual designs were more effective for older, less educated, or lower literacy respondents than for their counterparts.
The Eddington ratio-dependent ‘changing look’ events in NGC 2992
Authors: Guolo Muryel , Ruschel-Dutra Daniel , Grupe Dirk , Peterson Bradley M , Storchi-Bergmann Thaisa , Schimoia Jaderson , Nemmen Rodrigo , Robinson Andrew 
Published: September 2021

ABSTRACTWe present an analysis of historical multiwavelength emission of the `Changing Look' (CL) Active Galactic Nucleu (AGN) in NGC 2992, covering epochs ranging from 1978 to 2021, as well as new X-ray and optical spectra. The galaxy presents multiple Seyfert type transitions from Type 2 to intermediate-type, losing and regaining its Hα broad emission lines (BEL) recurrently. In X-rays, the source shows intrinsic variability with the absorption corrected luminosity varying by a factor of ∼ 40. We rule-out tidal disruption events or variable obscuration as causes of the type transitions, and show that the presence and the flux of th Hα BEL is directly correlated with the 2–10 keV X-ray luminosity (L2−10): the component disappears at L2−10 ≤ 2.6 × 1042 $\rm erg\, cm^{-2}\, s^{-1}$; this luminosity value translates into an Eddington ratio (λEdd) of ∼ 1 per cent. The λEdd in which the BEL transitions occur is the same as the critical value at which a state transition between a radiatively inefficient accretion flow and a thin accretion disk is expected, such similarity suggests that the AGN is operating at the threshold mass accretion rate between the two accretion modes. We find a correlation between the narrow Fe Kα flux and λEdd, and an anticorrelation between full-width at half maximum of Hα BEL and λEdd, in agreement with theoretical predictions. Two possible scenarios for type transitions are compatible with our results: either the dimming of the AGN continuum, which reduces the supply of ionizing photons available to excite the gas in the Broad Line Region (BLR), or the fading of the BLR structure itself occurs as the low accretion rate is not able to sustain the required cloud flow rate in a disc-wind BLR model.
improved Master for the LSS: fast and accurate analysis of the two-point power spectra and correlation functions
Authors: Singh Sukhdeep 
Published: September 2021

ABSTRACT
We review the methodology for measurements of two-point functions of the cosmological observables, both power spectra and correlation functions. For pseudo-Cℓ estimators, we will argue that the window-weighted overdensity field can yield more optimal measurements as the window acts as an inverse noise weight, an effect that becomes more important for surveys with a variable selection function. We then discuss the impact of approximations made in the Master algorithm and suggest improvements, the iMaster algorithm, which uses the theoretical model to give unbiased results for arbitrarily complex windows provided that the model satisfies weak accuracy conditions. The methodology of iMaster algorithm is also generalized to the correlation functions to reconstruct the binned power spectra, for E/B mode separation, or to properly convolve the correlation functions to account for the scale cuts in the Fourier space model. We also show that the errors in the window estimation lead to both additive and multiplicative effects on the overdensity field. Accurate estimation of window power can be required up to scales of ∼2ℓmax or larger. Mis-estimation of the window power leads to biases in the measured power spectra, which scale as ${\delta C_\ell }\sim M^W_{\ell \ell ^{\prime }}\delta W_{\ell ^{\prime }}$, where the $M^W_{\ell \ell ^{\prime }}$ scales as ∼(2ℓ + 1)Cℓ leading to effects that can be important at high ℓ. While the notation in this paper is geared towards photometric galaxy surveys, the discussion is equally applicable to spectroscopic galaxy, intensity mapping, and Cosmic Microwave Background radiation (CMB) surveys.