bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early diagnostics of severe combined immunodeficiencies
Authors: L. V. Kostiuchenko  
Published: December 2021

Severe combined immunodeficiency is a big group of genetically determined immunological defects with a profound quantitative and/or functional deficiency of T- and B-cells, and sometimes NK-cells. The article contains our own experience of observation of patients with severe combined immunodeficiencies to establish early clinical and laboratory markers of SCID. A clinical, genealogical and laboratory analysis of 22 SCID patients and a comparison group was performed, the most common symptoms of this kind of PID and the time of their appearance were identified. It was found that the SCID patients do not have specific sings up to the manifestation of clinical symptoms of infections, and as early signs of the disease can be considered an eventful family history with children deaths at early age and lymphopenia below 3.0 х109 / l in 77,3 % of patients that can be used as screening laboratory finding in our country. An algorithm for diagnosis of SCID was proposed and the feasibility of practical implementation of neonatal screening for this disease was discussed.
Clinical examples of the replacement dentition defects based on occlusal changes
Authors: O. V. Mitchenok  
Published: December 2021

This paper presents the most frequent reasons that arise in the treatment of orthopedic deformities of dentition and a violation of functional occlusion. When creating artificial dentition with the prosthesis it is necessary to take into account the fact how age-related changes of existing dentition defects affect the occlusal changes associated with other elements of the dentoalveolar system. Clinical examples of case histories which were presented by us indicate to orthopedic treatment with different orthopedic constructions without articulatory contacts when restoring dentition which led to complications.
Social background of premenstrual syndrome
Authors: L. V. Pakharenko  
Published: December 2021

The study involved 200 women with premenstrual syndrome (PMS). It was established that women with PMS tend to have increased number of divorces (χ2=2,37, p=0,12, OR=5,44, 95% CI 0,71-41,58, p=0,10), which is especially typical for women with neuropsychic diseases (χ2=5,99, p=0,01, OR=10,79, 95 % CI 1,36-85,47, p=0,02). Such factors as higher education (χ2=8,57, p=0,003, OR=2,67, 95 % CI 1,41-5,03, p=0,002) and intellectual occupation (χ2=4,29, p=0,04, OR=2,03, 95% CI 1,08-3,80, p=0,03) can be considered as markers of increased risk of PMS, which are most typical for neuropsychic diseases. Our study did not confirm the role of smoking and living in big cities as risk factors of this neuroendocrine syndrome.
The effect of 3,2'-spiro-pyrrole-2-oxindole derivate (compound R-86) pharmacoprophylactic application on development of cardiocerebral disfunction in the simulated intracerebral haemorrhage
Authors: I. O. Petryk  , L. B. Braverman  , O. A. Khodakivskyi  , I. L. Rokunets  
Published: December 2021

To perform monitoring of cardiac activity functional parameters and neurologic status in conditions of simulated hemorrhagic stroke along with pharmacoprophylactic administration of 3,2'-spiro-pyrrole-2-oxindole derivate. Materials and methods. Monitoring of cardiac activity functional parameters and neurologic status in conditions of simulated intracerebral haemorrhage (introduction of autologous blood into the internal cerebral capsule (20μl/ 100 g) was performed along with pharmacoprophylactic intragastric administration of 3,2'-spiro-pyrrole-2-oxindole derivate in conditionally effective dose of 10μl/ kg. Corvitin was chosen as a reference drug for intraperitoneal administration in dose of 10μl/ kg. Results and discussion. We determined that the acute period of hemorrhagic stroke in rats (introduction of autologous blood into the internal cerebral capsule (20μl/ 100 g) was accompanied with the moderate neurologic deficiency, sufficient degradation of the central hemodynamics and functional disorders of cardiac activity that indicated the cerebrocardiac syndrome. Pharmacoprophylactic administration of 3,2'-spiro-pyrrole-2-oxindole derivate compound R-86 (10μl/ kg, intragastric administration) as well as Corvitin (10μl/kg, intraperitoneal administration) had the prophylactic effect on development of cardiocerebral syndrome, which was exhibited by preventing the escalation of neurologic deficiency and stabilization of cardiovascular activity functional parameters. Summary. 3,2'-spiro-pyrrole-2-oxindole derivate compound R-86 is the prospective neurocardioprotector, which correlates with Corvitin by its protective effects on cerebrum and myocardium in the simulated intracerebral hemorrhage.
Total nephrectomy by endovideosurgical methods with transperitoneal access
Authors: A. A. Pidmurniak  
Published: December 2021

The article presents the results of clinical introduction of minimally invasive urological operations in patient with renal tumors in comparison with open urological operations. The methods of endovideosurgical operations with laparoscopic access were described. Advantages of minimally invasive methods were shown.
Hemodynamics in ischemia-reperfusion of rat’s brain in applying some infusion solutions
Authors: A. I. Semenenko  , B. A. Kondratskyi  , Y. Y. Kobeliatskyi  
Published: December 2021

In experiments on rats with modeled apoplectic attack (bilateral 20-minutes ischemia of the internal carotid arteries with further reperfusion), was established that the administration of HAES-LX-5% and Voluven at a dose of 2,5 ml/kg 2 times a day (5,0 mL/kg per day), every day, every 12 hours during the 7 days was accompanied by improved blood circulation in cerebral vessels (p<0,05) compared with animals treated with 0,9% NaCl solution and also to some extent inhibits the development of cerebrocardiac syndrome which manifested in the stabilization and restoration of arterial and central venous pressure.
Pathophysiological aspects of intestinal transplantation (reference review)
Authors: S. S. Palianytsia  , L. A. Panchenko  , E. V. Buslovych  , T. I. Davydova  , N. F. Sokolov  
Published: December 2021

Transplantation of the intestine is quite new and most effective treatment for short bowel syndrome (SBS). Improving early graft survival due to the reduction in the rate of acute rejection after transplantation while minimizing toxicity, achieved at the expense of significant progress in immunosuppression. Recently, the multi-visceral transplantation has been applied more and more widely. The article highlights the mechanisms of disorders that occur in bowel transplantation, possible ways to manage side effects with a view to long-term graft survival.
Human heart valves: development, macro- and microscopical structure, peculiarities of blood supply (reference review)
Authors: O. H. Popadynets  , O. V. Sahan  , N. M. Dubyna  
Published: December 2021

The heart has two similar each to other in structure inlet (atriaventricular) and two outlet (ventricularvascular) valvular apparatuses. The mitral (bicuspid) and tricuspid valves are atriaventricular heart valves. The aortic and pulmonary valves are ventricular-vascular heart valves. The valvular apparatus of the heart is the complex system, which includes: the fibrous ring, cusps, tendinous cords and papillary muscles. The last two components are characteristic for the atriaventricular valvular apparatuses and they are absent in the ventricular-vascular valvular apparatuses. The valvular apparatuses of aorta and pulmonary trunk have the fibrous rings, the wall of aorta/pulmonary trunk, semilunar cusps. The laying of the valvular apparatuses begins on early stages of embryonic development and finishes before the beginning of fetal period of the prenatal ontogenesis. The normal function of the heart and human body is dependent on the complex interaction of all components of the valvular apparatus of the heart. Many discussions of the development, structure with peculiari ties of the blood supply, the age changes remain in the fundamental investigations. The modern diagnostic and medical apparatuses, the possibilities of the modern methods of investigations require from scientists the renewal of the known facts about the valvular apparatuses of the heart. They might be useful as the theoretical and practical background which will deepen the understanding of the pathogenesis and the quality of heart diseases treatment.
Individual work at the students scientific circle of pharmacology department as a factor for professional competence formation
Authors: N. I. Voloshchuk  , O. M. Denysiuk  
Published: December 2021

The article deals with the role of student scientific circle as a form of self-education that teaches students to analyze and organize scientific information, conduct experimental research, make the interpretation of the results and make them public at various scientific conferences. The role of research work of students in educational process intensification in the study of pharmacology has been shown.
Red blood cell abnormalities occur in dogs with congenital ventricular outflow tract obstruction
Authors: Passavin Peggy , Chetboul Valérie , Poissonnier Camille , Saponaro Vittorio , Trehiou-Sechi Emilie , Alvarado Maria-Paz , Tissier Renaud , Lagrange Isabelle , Deshuillers Pierre 
Published: December 2021

Abstract

OBJECTIVE
To document RBC abnormalities in dogs with congenital ventricular outflow tract obstruction.

ANIMALS
62 dogs with pulmonic stenosis (PS) or aortic stenosis (AS) and 20 control dogs were recruited.

PROCEDURES
The proportions of RBCs that were schistocytes, acanthocytes, and keratocytes were assessed. Complete blood cell counts were performed. Tested variables included hemoglobin concentration, hematocrit, and erythrocyte count.

RESULTS
Median (interquartile range [IQR]) peak systolic Doppler-derived trans-stenotic pressure gradient (∆P) values were 161 mm Hg (108 to 215 mm Hg) and 134 mm Hg (125 to 165 mm Hg) for dogs with PS and AS, respectively. Hematologic abnormalities were detected in most dogs with AS or PS (54/62 [87%]) versus 8/20 [40%] in control dogs, with schistocytes found in 40 of 62 (65%; median, 0.1% RBCs; IQR, 0% to 0.3%), acanthocytes in 29 of 62 (47%; median, 0.3% RBCs; IQR, 0% to 0.9%), keratocytes in 39 of 62 (63%; median, 0% RBCs; IQR, 0% to 0.2%), and hemolytic anemia in 4 dogs with PS. No significant association was identified between these abnormalities and ∆P. However, 3 of 4 dogs with anemia had a ∆P > 200 mm Hg (range, 242 to 340 mm Hg). The dog with the highest ∆P value also had the most severe anemia and schistocytosis, and both resolved after balloon valvuloplasty.

CLINICAL RELEVANCE
Poikilocytosis is common in dogs with congenital ventricular outflow tract obstruction, with anemia only observed in few dogs with high ∆P values.
Iranian innovations in mosque lighting techniques: A historical survey
Authors: Moghaddasi Ahmad , Moghaddasi Mohammad Hossein , Hosseini Seyed Behshid 
Published: December 2021

Abstract
From the viewpoint of preserving the values of sustainable architecture, daylight in the interiors of mosques in hot and dry climates has always faced limitations. The need to use daylight to provide the required lighting and, in contrast, to prevent the scorching desert sun from entering the spaces led to innovative techniques in Iranian architecture. These techniques have gradually evolved along with the development of semantic concepts of space in different periods of Islamic architecture, which has resulted in slight differences in their application in mosque buildings. In this article, while analysing the place of light in mosque architecture, the standard techniques in lighting mosques located in Iran’s hot and dry climate are studied. The employed research method is a combination of qualitative and quantitative approaches. As the current historic-architectural research cannot be based solely on perception-based definitions, authors had to convert the conceptual features into a measurable index. To achieve this, a numerical index with the scale from 0 to 3 has been defined. The scoring was based on documents such as plans, images, etc. Although most case study objects were built over the centuries, they have general characteristics that distinguish them from a specific historical era. The authors studied the application of these techniques in some examples of selected mosques from four periods of Islamic architecture and present the results in the form of trend charts. Furthermore, they observed the principle of continuity in Iranian architecture from the historical period from the beginning of the Islamic period to the Qajar period, and, in accordance with the theoretical foundations of research, analysed the reasons for the ups and downs of each of the techniques.
Rhythmic ability decline in aging individuals: The role of movement task complexity
Authors: Iannarilli Flora , Vannozzi Giuseppe , Minganti Carlo , Capranica Laura , Pesce Caterina 
Published: December 2021

Abstract

Study aim: To investigate age-related changes in rhythmic reproduction ability in relation to the complexity of the adopted movement task.

Material and methods: A Stereophotogrammetric system was used to quantify individual rhythmic performances through motion analysis. Seventeen younger adult (age: 34.8 ± 4.2 yrs) and sixteen older adult (age: 69.9 ± 3.8 yrs) sedentary individuals volunteered for this study. Participants were administered a rhythmic test, which included three different rhythmic patterns to be reproduced by means of finger-tapping, foot-tapping and walking. Number of correct reproductions, time delays and rhythmic ratios were assessed and submitted to analysis of variance.

Results: For all rhythmic parameters, age-related differences emerged about rhythmic patterns and motor tasks. Older adults showed reduced accuracy as compared to their younger counterparts with a marked tendency to speed up beats reproduction (p < 0.05). Increased movement complexity negatively influenced rhythmic ability, with worst performances in the walking task (p < 0.05).

Conclusions: Complexity of the motor reproduction worsen rhythmic ability. Future research should focus on how specific rhythmic training with progressive movement task complexity could contrast this age-related decline.
The Effect of Different Decision-Making Methods on Multi-Objective Optimisation of Predictive Torque Control Strategy
Authors: Gurel Aycan , Zerdali Emrah 
Published: December 2021

Abstract
Today, a clear trend in electrification process has emerged in all areas to cope with carbon emissions. For this purpose, the widespread use of electric cars and wind energy conversion systems has increased the attention and importance of electric machines. To overcome limitations in mature control techniques, model predictive control (MPC) strategies have been proposed. Of these strategies, predictive torque control (PTC) has been well accepted in the control of electric machines. However, it suffers from the selection of weighting factors in the cost function. In this paper, the weighting factor associated with the flux error term is optimised by the non-dominated sorting genetic algorithm (NSGA-II) algorithm through torque and flux errors. The NSGA-II algorithm generates a set of optimal solutions called Pareto front solutions, and a possible solution must be selected from among the Pareto front solutions for use in the PTC strategy. Unlike the current literature, three decision-making methods are applied to the Pareto front solutions and the weighting factors selected by each method are tested under different operating conditions in terms of torque ripples, flux ripples, cur-rent harmonics and average switching frequencies. Finally, a decision-making method is recommended.
CONTROL AND MEASURED MATERIALS ON DISCIPLINE «THEORY AND TECHNOLOGY OF DEVELOPMENT OF MATHEMATICAL REPRESENTATIONS IN CHILDREN»
Authors: Яковлева Т.П. 
Published: December 2021

The article presents the control and measurement materials (CMM) for the discipline «Theory and technology of development of mathematical representations in children.»CMMs are presented in the form of tests.
В статье представлены контрольно-измерительные материалы (КИМ) по дисциплине «Теория и технология развития математических представлений у детей». КИМы представлены в виде тестов.
STABILITY OF THE REST POINTS FRACTIONAL OSCILLATOR FITZHUGH-NAGUMO
Authors: Липко О.Д. 
Published: December 2021

В работе с помощью качественного анализа были исследованы на устойчивость точки покоя дробного осциллятора ФитцХью-Нагумо в соизмеримом и несоизмеримом случаях. Для соответвующей точки покоя, с помощью численного метода теории конечно-разностных схем, была построена фазовая траектория. Показано, что точки покоя могут быть как асимптотически устойчивыми, что соответствуют устойчивым фокусам, так и являться асимптотически неустойчивыми (неустойчивыми фокусами), причем для них фазовые таректории, как правило, выходят на предельный цикл.
In this paper, using the qualitative analysis, we studied the stability of the point of rest of the fractional oscillator FitzHugh-Nagumo in commensurate and incommensurable cases. For the corresponding point of rest, using the numerical method of the theory of finite difference schemes, phase trajectories were constructed. It is shown that quiescent points can be both asymptotically stable, which correspond to stable focus, and are asymptotically unstable (unstable focus), and for them the phase trajectories usually go to the limit cycle.
ON A GENERALIZED MATHEMATICAL MODEL OF MALTHUS
Authors: Лосанова Ф.М. , Кенетова Р.О. 
Published: December 2021

В работе рассмотрено обобщенное уравнение Мальтуса, описывающее одновидную по пуляцию. Решена задача Коши для случаев 0 1 и 1 2.
The paper considers the generalized Malthus equation describing a singlespecies population. Solved the Cauchy problem for cases 0 1 and 1 2.
HARDWARE AND SOFTWARE COMPLEX OF AUGMENTATION COMMUNICATION SYSTEM ON THE BASIS OF EYETRACKING TECHNOLOGYS
Authors: Грушко Ю.В. 
Published: December 2021

В работе представлено описание разработанного АПК и реализованного алгоритма айтрекинга (с использованием сверточных нейронных сетей и методов математической морфологии), позволяющего людям, страдающим нарушениями двигательных функций и нервнопаралитическими синдромами, осуществлять процесс коммуникации с внешним миром, посредством управления компьютером и печати текста движением глаз.
The paper presents a description of the developed APC and implemented the algorithm of EyeTracking (based on convolutional neural networks and morphological analysis), which allows people suffering from motor dysfunction and neuroparalytic syndromes to carry out the process of communication with the outside world through computer control and text printing by eye movement
THE INTERACTION POTENTIALS OF THE FULLERENE C60 MOLECULE AND CARBON NANOPARTICLES WITH A THICK GRAPHITE PLATE
Authors: Бухурова М.М. 
Published: December 2021

В работе исследована краевая задача для модельного уравнения смешанного парабологиперболического типа третьего порядка. Доказана теорема о единственности и существовании регулярного решения исследуемой задачи. Решение исследуемой задачи выписано в явном виде.
In this paper, a boundary value problem for a model inhomogeneous mixed parabolichyperbolic type equation of third order is investigated. A theorem on uniqueness and the existence of a regular solution of the problem under investigation is proved. The solution of the investigated problem is written out in an explicit form.
LUMINESCENCE OF YAG:Ce DOPED WITH SILVER NANOPARTICLES
Authors: Кравцов Александр Александрович , Чикулина Ирина Сергеевна , Вакалов Дмитрий Сергеевич , Чапура Олег Михайлович , Крандиевский Святослав Олегович , Девицкий Олег Васильевич , Лапин Вячеслав Анатольевич 
Published: December 2021

В работе впервые было исследовано влияние наночастиц серебра на люминесценцию иттрий-алюминиевого граната, легированного церием. С помощью метода химического восстановления был синтезирован золь с размером наночастиц серебра ≈100 нм. Керамический порошок люминофора иттрий-алюминиевого граната, легированного церием, был получен методом двухстадийного осаждения в уротропин. Золь наночастиц серебра в концентрациях от 0,125 до 0,1 мл вводили в порошок-прекурсор перед прокаливанием. Было показано, что при данном способе введения наночастиц серебра интенсивность фотолюминесценции возрастала по сравнению с эталоном. Оптимальной концентрацией в рамках исследования являлась концентрация 0,25 мл. При данной концентрации увеличение интенсивности фотолюминесценции на длине волны 540 нм составило порядка 10%. Проведенные исследования показали, что наночастицы серебра могут с успехом применяться для увеличения яркости люминофора иттрий-алюминиевого граната, легированного церием, без искажения и ухудшения спектральных характеристик.
This work was the first to study the effect of silver nanoparticles on the luminescence of cerium doped yttrium-aluminum garnet. A sol with the size of silver nanoparticles of ≈100 nm was synthesized using the method of chemical reduction. Phosphor ceramic powder of the yttrium-aluminum garnet doped with cerium was obtained by the two-stage precipitation method. The silver nanoparticles sol was introduced into the precursor powder before calcination in concentrations from 0,125 to 0,1 ml. It was shown that the photoluminescence intensity increased in comparison with the reference when we used this method of introducing silver nanoparticles. The optimal concentration within the study was 0,25 ml. At this concentration, the increase in the photoluminescence intensity at a wavelength of 540 nm was about 10 %. Studies have shown that silver nanoparticles can be successfully used to increase the brightness of the phosphor of the yttrium-aluminum garnet doped with cerium without distortion and deterioration of spectral characteristics.
História de mulheres educadoras: dos movimentos sociais latinoamericanos Ã figura feminina nas contradições sociais do século XXI
Authors: Reichert Débora Aparecida Rosa 
Published: December 2021

Para refletir, de que forma a história de mulheres educadoras desde os movimentos sociais latino-americanos Ã figura feminina nas contradições sociais do século XXI, podem colaborar para uma construção social baseada na igualdade de direitos, pensamos: As transformações da sociedade tanto no que diz respeito ao fator econômico, ou acerca do consumo presente no sistema do capital, as questões de gênero, a influência da mídia na sociedade, e principalmente a permanência da mulher como protagonista neste século, vem fortalecendo os movimentos sociais já existentes cujo os direitos das mulheres são principal foco bem como a inspiração cada vez mais forte de novos movimentos, como exemplo desta década temos o movimento da teologia feminista, que possibilita a reflexão do papel da mulher na religião sem a submissão histórica dos antepassados. Diante dos debates, muitas perguntas surgem, pois há contradições destas relações que precisam ser pensadas