bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trichuris muris as a tool for holistic discovery research: from translational research to environmental bio-tagging
Authors: Mair Iris , Else Kathryn J. , Forman Ruth 
Published: May 2021

AbstractTrichuris spp. (whipworms) are intestinal nematode parasites which cause chronic infections associated with significant morbidities. Trichuris muris in a mouse is the most well studied of the whipworms and research on this species has been approached from a number of different disciplines. Research on T. muris in a laboratory mouse has provided vital insights into the host–parasite interaction through analyses of the immune responses to infection, identifying factors underpinning host susceptibility and resistance. Laboratory studies have also informed strategies for disease control through anthelmintics and vaccine research. On the contrary, research on naturally occurring infections with Trichuris spp. allows the analysis of the host–parasite co-evolutionary relationships and parasite genetic diversity. Furthermore, ecological studies utilizing Trichuris have aided our knowledge of the intricate relationships amongst parasite, host and environment. More recently, studies in wild and semi-wild settings have combined the strengths of the model organism of the house mouse with the complexities of context-dependent physiological responses to infection. This review celebrates the extraordinarily broad range of beneficiaries of whipworm research, from immunologists and parasitologists, through epidemiologists, ecologists and evolutionary biologists to the veterinary and medical communities.
Food System Transformation and the Role of Gene Technology: An Ethical Analysis
Authors: Thompson Paul B. 
Published: May 2021

AbstractThe global food system exhibits dizzying complexity, with interaction among social, economic, biological, and technological factors. Opposition to the first generation of plants and animals transformed through rDNA-enabled gene transfer (so-called GMOs) has been a signature episode in resistance to the forces of industrialization and globalization in the food system. Yet agricultural scientists continue to tout gene technology as an essential component in meeting future global food needs. An ethical analysis of the debate over gene technologies reveals the details that matter. On the one hand, alternative regimes for institutionalizing gene technology (through regulation, trade policy, and intellectual property law) could mitigate injustices suffered by politically marginalized and economically disadvantaged actors in the food system, especially smallholding farmers in less industrialized economies. On the other hand, GMO opposition has been singularly effective in mobilizing citizens of affluent countries against policies and practices that lie at the heart of these same injustices. As part of the roundtable, “Ethics and the Future of the Global Food System,” this essay argues that charting a middle course that realizes the benefits of gene technology while blocking its use in the perpetration of unjust harms may require a more detailed grasp of intricacies in the food system than even motivated bystanders are willing to develop.
Subversive Future Seeks Like-Minded Model: On the Mismatch between Visions of Food Sovereignty Futures and Quantified Scenarios of Global Food Futures
Authors: Saghai Yashar 
Published: May 2021

AbstractWill we, by 2050, be able to feed a rapidly growing population with healthy and sustainably grown food in a world threatened by systemic environmental crises? There are too many uncertainties for us to predict the long-term evolution of the global agri-food system, but we can explore a wide range of futures to inform policymaking and public debate on the future of food. This is typically done by creating scenarios (story lines that vividly describe what different futures could look like) and quantifying them with computer simulation models to get numerical estimates of how different aspects of the global agri-food system might evolve under different hypotheses. Among the many scenarios produced over the last twenty years, one would expect to see the future advocated by the food sovereignty movement, which claims to represent roughly two hundred million self-described “peasants” (small farmers) worldwide. This movement defends a vision of the future based on relocalized, sustainable, and just agri-food systems, self-governed through direct and participatory democratic processes. Yet, food sovereignty is conspicuously absent from quantified scenarios of global food futures. As part of the roundtable, “Ethics and the Future of the Global Food System,” this essay identifies seven obstacles that undermine the creation of food sovereignty scenarios by examining two attempts at crafting such scenarios.
Resources for the People—but Who Are the People? Mistaken Nationalism in Resource Sovereignty
Authors: Kutz Christopher 
Published: May 2021

AbstractArguments about the ownership of natural resources have focused on the claims of cosmopolitans, who urge an equality of global claims to resources, and resource sovereigntists, who argue that national peoples are the proper owners of their resources. This focus is mistaken: Whatever one believes about the in-principle claims of the global community, there remains the practical question of how the national surplus is to be distributed. And in addressing this question, we must look at a distinction heretofore ignored in resource discussions—that between resident workers and citizens. I argue that the extracted value of natural resources should benefit all residents of the states in which they are found, not merely all citizens. By contrast, control of natural resources should be vested in a democratic citizenry, who are nonetheless normatively constrained by the distributive principle described above. I illustrate the argument with data showing the gap, especially in the Gulf States, between principles that allocate benefits to all citizens vs. to all resident workers. My argument is grounded in a broader theory of collective agency as it applies to questions of distributive justice, and it is aimed not only to criticize practices in the Gulf but to support the more inclusive resource policies found in democracies.
Rethinking the Nature of States and Political Violence
Authors: Henschke Adam 
Published: May 2021

AbstractIt is a long-held belief that states must retain the monopoly over political violence in order to be states, and to survive. However, there are recent criticisms of this view forcing us to consider not just the state's use of political violence but the very nature of the state. Elizabeth Frazer and Kimberly Hutchings's Can Political Violence Ever Be Justified? argues that it cannot. Ned Dobos's Ethics, Security, and the War-Machine raises a series of arguments against states having standing militaries, and Alex Vitale's The End of Policing similarly raises a series of arguments against the institution of the police. In this review essay, I suggest that these arguments all force us to revisit the very nature of the state. There are concerns about simply abolishing these institutions of political violence, but we can indeed conceive of states without the monopoly on violence.
Choices, challenges, and constraints: a pragmatic examination of the limits of mental age matching in empirical research
Authors: Russo N. , Kaplan-Kahn E. A. , Wilson J. , Criss A. , Burack J. A. 
Published: May 2021

AbstractThe work of Ed Zigler spans decades of research all singularly dedicated to using science to improve the lives of children facing different challenges. The focus of this article is on one of Zigler's numerous lines of work: advocating for the practice of mental age (MA) matching in empirical research, wherein groups of individuals are matched on the basis of developmental level, rather than chronological age. While MA matching practices represented a paradigm shift that provided the seeds from which the developmental approach to developmental disability sprouted, it is not without its own limits. Here, we examine and test the underlying assumption of linearity inherent in MA matching using three commonly used IQ measures. Results provide practical constraints of using MA matching, a solution which we hope refines future clinical and empirical practices, furthering Zigler's legacy of continued commitment to compassionate, meaningful, and rigorous science in the service of children.
SALVAGE AND RESCUE ARCHAEOLOGY INSIDE ANCIENT TULA: RECENT DISCOVERIES AND REVELATIONS
Authors: Gamboa Cabezas Luís , Healan Dan M. 
Published: May 2021

AbstractThis article presents the results of seven archaeological salvage and rescue projects that resulted in new information on settlement at Tula, Hidalgo that includes materials and evidence of activities rarely or never before encountered at Tula. Several localities exhibited evidence of craft activities that included the production of basalt megaliths, human and animal figurines, and the processing of human skulls. One locality was the scene of elaborate ritual involving the mass sacrifice of children, and another was the scene of elaborate ritual destruction and offerings involving some of the most sumptuous objects yet found at Tula. One of the most remarkable aspects of the wealth of information and material culture obtained was that these were salvage and rescue operations undertaken with limited time and resources in localities determined by factors in which previous archaeological knowledge played no guiding role. These investigations indicate that despite the extensive damage suffered by Tula outside the protected area, much of the old city still remains for researchers for the immediate future.
WARRIORS, KINGS, AND TEOHUAQUE AT TULA: A RECONSIDERATION OF THE SO-CALLED “WARRIOR PILLARS” ATOP PYRAMID B
Authors: Jiménez García Elizabeth 
Published: May 2021

AbstractPyramid B was one of the most important buildings in the sacred precinct of the Early Postclassic city of Tula, Hidalgo. On its summit was a temple supported by anthropomorphic and zoomorphic columns and four pillars containing the reliefs of 16 individuals and other images. Based on comparative analysis with other archaeological specimens and images from conquest era codices, I propose that all 16 individuals were warrior-kings in sacred dress bearing a suite of weapons associated with the Tollan-Xicocotitlan elite.
CHILD SACRIFICE IN TULA: A BIOARCHAEOLOGICAL STUDY
Authors: Medrano Enríquez Angélica María 
Published: May 2021

AbstractRecent salvage excavations conducted in the Early Postclassic city of Tula, Hidalgo, exposed a residential compound containing an open patio, beneath which was discovered a massive burial, designated Feature 5. Human remains involving a minimum of 49 individuals were discovered, many of whom were arranged in a sitting or squatting position. The majority of individuals, including all of the latter, were young children. The bioarchaeological analysis suggests that they were sacrificed. Many individuals exhibited anthropogenic modification, including cut marks on the skull and postcranial skeleton, indicating the children had been flayed. Some individuals were represented only by the skull and cervical vertebrae, suggesting decapitation. The individuals appeared to be in bad health, a common attribute of children sacrificed to Tlaloc by the Aztecs. According to ethnohistorical sources, children offered to Tlaloc commonly had their throats slit, although this practice was not identified among the individuals in Feature 5, possibly owing to their young age. Sacrifice also may have been made to Xipe Totec, as suggested by the evidence of flaying and the presence of a large hollow sculpture of the deity located in an adjacent residential compound, a deity who has been also linked to human sacrifice related to regeneration and fertility.
WORKING AS EQUAL MORAL AGENTS
Authors: Tsuruda Sabine 
Published: May 2021

ABSTRACTThis article develops and advances a liberal ideal of equality for evaluating the lawful scope of employer control over employees. It argues that, in addition to attending to discrimination and bargaining power asymmetries, we should ensure that our laws treat workers as the moral equals of their bosses more broadly—as people with equally weighty claims to exercising agency over their own values and lives. To illustrate, the article explains that employer control over workplace expression can preclude colleagues from communicating with each other as moral equals and can compromise employees’ abilities to exercise agency over their own characters. It then discusses how our agential interests in workplace expression can guide legal reform.
Interreligious Relations with No Self: A Mystical Path to Omnilogue?
Authors: STEPIEN RAFAL K. 
Published: May 2021

AbstractVarious models of interreligious relations have been proposed in recent scholarship, including most prominently the several varieties of inclusivism, exclusivism, and pluralism. One abiding presupposition shared across these models takes the religious adherent (or community of adherents) as a unified individual (or collective of such individuals). This assumption overlooks an important feature of the mystical strains of religiosity, which is to negate selfhood. This article seeks to problematize standard scholarly models of interreligious relations by working through and applying to them such mystical understandings of (non-)selfhood, with particular focus on the Islamic mystics Abū Yazīd al-Bisṭamī, Abū l-Qāsem al-Junayd, ʿAbd al-Karīm ibn Hawāzin al-Qushayrī, Farīd al-Dīn ʿAṭṭār Nayshābūrī, and Muḥyiddīn Ibn al-ʿArabī. Based on this textual study, I propose an alternative to interreligious dialogue more adequately termed ‘polyglot monologue’ or, in order to avoid pluralistic implications, ‘omnilogue’.
Orbán Urbi et Orbi: Christianity as a Nodal Point of Radical-right Populism
Authors: Lamour Christian 
Published: May 2021

AbstractThere is one European state leader from the moderate Christian-democrat center right who has developed a discourse and policies showing his progressive move toward the radical right: Viktor Orbán. Can Christianity be considered from a Laclauian perspective, as a “nodal point” of Orbán's radical right discourse; that is, a key element around which his antagonistic narratives are structured? Based on an analysis of segments of Orbán's speeches between 2014 and 2019 that mention Christianity, the research reveals that this religion is a nodal point for three main reasons: (1) the density of Christian references used to shape a negative and antagonistic discourse, strategically adjusted to his audience; (2) the use of Christianity to ground the three ideological pillars of the radical right (populism, nativism, and authoritarianism); and (3) the mobilization of Christianity to organize a hegemonic struggle against the dominant political force that has defined the meaning of this religion in the European public sphere—the moderate center right.
A mathematical model for sidelobe level optimization of variable inclination continuous transverse stub antenna
Authors: Wang Kexin , Lei Xue , Gao Jun , Li Tianpeng , Zhao Mingyang 
Published: May 2021

AbstractA mathematical model of variable inclination continuous transverse stub (VICTS) antenna for low sidelobe design is proposed in this paper. VICTS antenna is an antenna with continuous transverse stubs on the parallel-plate waveguide and additional branches attached to the transverse stubs to generate radiation. The antenna using this technique has high aperture efficiency and keeps a significant solution for high-gain antenna. However, the sidelobe level (SLL) of this antenna is relatively high and increases continuously as the pitch angle decreases. This paper presents a fast calculation model for the SLL of VICTS antennas using leaky-wave theory and antenna array theory. The full-wave simulation results and model calculation results are in good agreement, so this model can be used for SLL suppression of VICTS antennas in different frequency bands. By controlling the aperture field distribution to be tapered, the SLL is suppressed to − 23.7 dB using this mathematical model.
Compact bandwidth tunable IF filters for reconfigurable converters
Authors: Ni Jia , Hong Jiasheng , Iglesias Petronilo Martin 
Published: May 2021

AbstractThis paper aims to present some outcomes from a European Space Agency (ESA) Technology Research Programme (TRP) project on R&D of new design techniques, concepts, and filtering configurations for tunable IF (intermediate frequency) filters with a compact footprint, wide bandwidth tuning range (covering from 49 to 478 MHz at f0 = 1 GHz) as well as equivalent high-Q performance (i.e. low insertion loss variation and high selectivity by using low-Q resonators). In order to obtain a wide tuning range, the proposed filtering configuration utilizes a new tuning technique that only necessitates control of coupling values with simple DC control circuits, without the need of tuning the electrical length of resonators to avoid deviating the center frequency. Furthermore, in order to achieve the equivalent high-Q performance, a novel lossy technique by using a centrally resistor-loaded half-wavelength resonator is adopted. For the proof of concept, a six-pole prototype filter is designed, fabricated, and tested.
Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019
Authors: Yang Xiaorong , Fang Yuan , Chen Hui , Zhang Tongchao , Yin Xiaolin , Man Jinyu , Yang Lejin , Lu Ming 
Published: May 2021

Abstract

Aims
Anxiety disorders are widespread across the world. A systematic understanding of the disease burden, temporal trend and risk factors of anxiety disorders provides the essential foundation for targeted public policies on mental health at the national, regional, and global levels.

Methods
The estimation of anxiety disorders in the Global Burden of Disease Study 2019 using systematic review was conducted to describe incidence, prevalence and disability-adjusted life years (DALYs) in 204 countries and regions from 1990 to 2019. We calculated the estimated annual percentage change (EAPC) to quantify the temporal trends in anxiety disorders burden by sex, region and age over the past 30 years and analysed the impact of epidemiological and demographic changes on anxiety disorders.

Results
Globally, 45.82 [95% uncertainty interval (UI): 37.14, 55.62] million incident cases of anxiety disorders, 301.39 million (95% UI: 252.63, 356.00) prevalent cases and 28.68 (95% UI: 19.86, 39.32) million DALYs were estimated in 2019. Although the overall age-standardised burden rate of anxiety disorders remained stable over the past three decades, the latest absolute number of anxiety disorders increased by 50% from 1990. We observed huge disparities in both age-standardised burden rate and changing trend of anxiety disorders in sex, country and age. In 2019, 7.07% of the global DALYs due to anxiety disorders were attributable to bullying victimisation, mainly among the population aged 5–39 years, and the proportion increased in almost all countries and territories compared with 1990.

Conclusion
Anxiety disorder is still the most common mental illness in the world and has a striking impact on the global burden of disease. Controlling potential risk factors, such as bullying, establishing effective mental health knowledge dissemination and diversifying intervention strategies adapted to specific characteristics will reduce the burden of anxiety disorders.
Evaluation of Long‐Term Temperature Trend and Variability in CMIP6 Multimodel Ensemble
Authors: Duan Yanan , Kumar Sanjiv , Kinter James L. 
Published: May 2021

AbstractThis study conducts a robust assessment of the Coupled Model Intercomparison Project Phase 6 to capture the observed temperature trends and variability at global and regional scales. The warming rate in the second half of the twentieth century (0.19°C/decade) is twice as large as in the full analysis period (1901–2014; 0.10°C/decade). Multidecadal climate variability results in considerable uncertainties in the regional temperature trend, but the multidecadal variability does not represent a statistically significant trend. Globally, the spatial pattern of trends is most similar among ensemble members of the same model, then among climate models, and the least similar between models and observations. The structural uncertainty and internal variability of climate models provide a range of temperature trends that generally encompass the regional scale observations. Some single model large ensembles also have variability comparable to the multimodel large ensemble, encompassing the regional scale observations.
Innate immune sensing of coronavirus and viral evasion strategies
Authors: Kasuga Yusuke , Zhu Baohui , Jang Kyoung-Jin , Yoo Ji-Seung 
Published: May 2021

AbstractThe innate immune system is the first line of the host defense program against pathogens and harmful substances. Antiviral innate immune responses can be triggered by multiple cellular receptors sensing viral components. The activated innate immune system produces interferons (IFNs) and cytokines that perform antiviral functions to eliminate invading viruses. Coronaviruses are single-stranded, positive-sense RNA viruses that have a broad range of animal hosts. Coronaviruses have evolved multiple means to evade host antiviral immune responses. Successful immune evasion by coronaviruses may enable the viruses to adapt to multiple species of host organisms. Coronavirus transmission from zoonotic hosts to humans has caused serious illnesses, such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and coronavirus disease-2019 (COVID-19), resulting in global health and economic crises. In this review, we summarize the current knowledge of the mechanisms underlying host sensing of and innate immune responses against coronavirus invasion, as well as host immune evasion strategies of coronaviruses.
Severe fever with thrombocytopenia syndrome virus: emerging novel phlebovirus and their control strategy
Authors: Casel Mark Anthony , Park Su Jin , Choi Young Ki 
Published: May 2021

AbstractAn emerging infectious disease first identified in central China in 2009, severe fever with thrombocytopenia syndrome (SFTS) was found to be caused by a novel phlebovirus. Since SFTSV was first identified, epidemics have occurred in several East Asian countries. With the escalating incidence of SFTS and the rapid, worldwide spread of SFTSV vector, it is clear this virus has pandemic potential and presents an impending global public health threat. In this review, we concisely summarize the latest findings regarding SFTSV, including vector and virus transmission, genotype diversity and epidemiology, probable pathogenic mechanism, and clinical presentation of human SFTS. Ticks most likely transmit SFTSV to animals including humans; however, human-to-human transmission has been reported. The majority of arbovirus transmission cycle includes vertebrate hosts, and potential reservoirs include a variety of both domestic and wild animals. Reports of the seroprevalence of SFTSV in both wild and domestic animals raises the probability that domestic animals act as amplifying hosts for the virus. Major clinical manifestation of human SFTS infection is high fever, thrombocytopenia, leukocytopenia, gastrointestinal symptoms, and a high case-fatality rate. Several animal models were developed to further understand the pathogenesis of the virus and aid in the discovery of therapeutics and preventive measures.