bluuebunny/crossref_metadata_2025_split huggingface dataset:
Im Vestibül der Algorithmen
Authors: Bohn Anna 
Published: October 2021

Abstract
Online-access to audiovisual content is rapidly changing the system of film distribution and film presentation. The streaming portal acts as a threshold for online access to moving image works. Algorithms and artificial intelligence are increasingly taking over the selection and curation of audiovisual content and direct viewers’ attention via personalised recommendation systems. The article outlines the market development towards online access to audiovisual content and analyses selected aspects such as artwork (thumbnails) and genres to explore the functionalities of accessory (paratexts) to the film for recommendation systems in video streaming portals and data analysis. From the analysis, the article derives preliminary considerations on requirements that result from the use of artificial intelligence technologies for promoting film and visual literacy in cultural heritage institutions.
A. W. Schlegels Korrespondenz – kollaborativ!
Authors: Strobel Jochen 
Published: October 2021

Abstract
The paper appeals for a re-examination of the digital scholarly edition of letters informed by a ‘theory of practice’ appropriate to a project environment. The genre letter seen as a means of communication and the use of digital media tools are emphasised, the use of which in no way precludes keeping with established scholarly critical edition standards. The ‘behind the scenes’ of the project The Digital Edition of August Wilhelm Schlegel’s Correspondence is discussed, as are, in a more universal sense, Bourdieu’s critical ideas of theory and practice as applied to digital letter edition projects and their interests.
Zum Briefwechsel von Georg Trakl und dem Kurt Wolff Verlag
Authors: Unterkircher Anton 
Published: October 2021

Abstract
The correspondence between Georg Trakl and the Kurt Wolff publishing house can serve as an example to demonstrate the different approaches of the two historical-critical Trakl editions. As about half of the letters are undated, the editors often had to guess their chronology. The already reconstructed letters are especially problematic because their sources are letters with an uncertain dating. In this paper, three letters are newly dated. Moreover, the double publication of a reconstructed and a surviving letter can be proved.
Analysis of flow pattern characteristics and strengthening mechanism of co-rotating and counter-rotating mixing with double impellers on different string shafts
Authors: Li Haotian , Wang Shibo , Wang Hua , Xu Jianxin , Xiao Qingtai , Fan Yuewei 
Published: October 2021

Abstract
Based on two cases of the double impellers on different shafts in the co-rotating and counter-rotating, the distribution of the velocity, streamline, turbulent kinetic energy, and turbulent energy dissipation rate are obtained through three-dimensional unsteady numerical simulation. Very good agreements between experimental and numerical results have been obtained. The hydrometallurgy purification experimental platform was built with the size of one third of the simulated. The results show that the mechanical string mixing system with double impellers on different shafts can form a more obvious convection effect in the central area of the double impellers, which can effectively break the mixing isolation region and improve the mixing effect. In the co-rotating case, the two impellers can generate strong convection in the central area and form an interactive vortex and a high-speed flow channel between the two impellers. while the convection formed by counter-rotating case is weaker and the vortex structures are independent of each other. The counter-rotating system performs better in the macro momentum transfer and the co-rotating system performs better in the micro-mixing level. In the experiments of hydrometallurgy purification, 7.93% more energy is used in the co-rotating system than that of the counter-rotating system. The average energy consumed by co-rotating in the process of purifying every one percent of Cd2+ ions are 8.65% lower than that of counter-rotating. The co-rotating system can improve microscopic mass transfer effect and finally save energy and time compared to the counter-rotating system.
Exploring the scope of homoeopathy in combating the unfortunate consequences of post-COVID-19 survivors based on non-COVID conditions: a narrative review
Authors: Dixit Ashish Kumar , Giri Nibha , Singh Shishir 
Published: October 2021

Abstract

Objectives
The long-term consequences of COVID-19 survivors care and post-coronavirus infection are not yet well understood. The review aims to see whether homoeopathy can help COVID-19 survivors recover from its consequences and improve their quality of life.

Content
A systematic search of published articles for post-COVID sequelae and the impact of Homoeopathy were conducted. For the literature search, the major electronic bio-medical database PubMed/MEDLINE was used. In addition, supplementary searches were conducted through the references of those published articles.

Summary
A total of 113 records were identified of which 61 studies included for this review. Homoeopathy is effective in the treatment of mental disorders including anxiety and depressive disorder (ADD), some research studies have found, although systematic reviews disagree. Likewise, some medical societies denounce homoeopathy for pain management; other literature shows that it can be used to treat pain effectively. Homoeopathy can aid in the treatment of cardiovascular diseases, as Crataegus, a homoeopathic medication, was found to be just as effective as a standard angiotensin-converting enzyme (ACE) inhibitor and diuretic treatment for minor cardiac insufficiency. The outcomes for Chronic Fatigue Syndrome (CFS), Influenza, and Acute Respiratory Tract Infections (ARTIs) are also promising.

Outlook
Based on the results of homoeopathy in non-COVID conditions, it can be thought of in the management of post-COVID-19 outcomes. Consequently, we propose that while investigating post-COVID-19 patient rehabilitation, homoeopathic management may be included as part of the follow-up route and as much data as possible in the context of homoeopathy should be collected, so that in future, the role of homoeopathy in dealing with it can be better demonstrated.
A renaissance in the treatment of diabetic kidney disease, hypertension in chronic kidney disease, and beyond
Authors: Yahr Jordana , Calle Juan , Taliercio Jonathan J. 
Published: October 2021

Abstract
Chronic kidney disease (CKD) affects approximately 15% of the US population and is associated with significant cardiovascular morbidity and mortality. The two leading causes of end stage kidney disease are hypertension and diabetes mellitus, both of which are modifiable risk factors. The cornerstones of CKD care include early detection, management of associated risk factors, modification of cardiovascular disease risk, slowing progression of disease, and management of complications including anemia, acid base disturbance, and mineral and bone disorders. For the last 20 years, renin-angiotensin system inhibitors were the mainstay treatment for proteinuric diabetic and nondiabetic kidney disease. Recently, new therapies such as sodium-glucose linked transporter 2 inhibitors, have emerged as powerful tools in the treatment of CKD with indications in both diabetic and nondiabetic kidney disease. In this article, we define CKD staging, review new hypertension and diabetic guidelines for CKD patients, and discuss major trials for new potential therapies in CKD, particularly diabetic kidney disease. We will provide practical guidance for primary care physicians to diagnose CKD and implement these agents early in the disease course to prevent the progression of disease and reduce the morbidity and mortality of this vulnerable population.
Two Japanese siblings with arginase-1 deficiency identified using a novel frameshift mutation of ARG1 (p.Lys41Thrfs∗2)
Authors: Nakajima Hisakazu , Fukuhara Shota 
Published: October 2021

Abstract
We described two Japanese siblings with arginase-1 (ARG1) deficiency. A 10-year-old girl (the proband and elder sister) was referred to our hospital complaining about her short stature. We diagnosed her with ARG1 deficiency, possibly with elevated levels of blood ammonia and plasma arginine. Her younger sister was found to have spastic paraparesis in her lower extremities and short stature at the age of 4 years. The younger sister also had high levels of plasma arginine, instead of normal levels of blood ammonia. Interestingly, they also prefer to avoid protein-rich foods such as meat, soybeans, cow milk, and dairy products. Genetic testing identified compound heterozygous mutations (c.121_122insCTT [p.Lys41Thrfs∗2] and c.298G>A [p.Asp100Asn]) in the ARG1 gene. The ARG1 mutation of p.Lys41Thrfs∗2 is a novel pathogenic mutation according to open databases and literature.
Clinical profile, etiology, and diagnostic challenges of primary adrenal insufficiency in Sudanese children: 14-years’ experience from a resource limited setting
Authors: Musa Salwa A. , Hassan Samar S. , Ahmed Amna I. , Ngwiri Thomas , Fadlalbari Ghassan F. , Ibrahim Areej A. , Babiker Omer O. , Abdullah Mohamed A. 
Published: October 2021

Abstract

Objectives
Primary adrenal insufficiency (PAI) in children is an uncommon condition. Congenital adrenal hyperplasia (CAH) is the commonest cause followed by autoimmune disorders. Diagnosis and management are challenging especially in resource-limited settings. Studies from Africa are scanty and here we describe for the first time the clinical presentation, possible etiologies, and challenges in diagnosis and management of PAI in a large cohort of Sudanese children.

Methods
This was a descriptive hospital-based study where all patients diagnosed with PAI between 2006 and 2020 were reviewed. The diagnosis was based on clinical presentation, low morning cortisol ± high adrenocorticotropic hormone (ACTH), or inadequate response of cortisol to synacthen stimulation. Challenges faced in diagnosis and management were identified.

Results
From 422 PAI suspected patients, 309 (73.2%) had CAH, and 33 (7.8%) had PAI-like symptoms and were not furtherly discussed. Eighty patients (19%) had fulfilled the study criteria: 29 had Allgrove syndrome, nine auto-immune polyendocrinopathy syndrome, seven adrenoleukodystrophy, and one had an adrenal hemorrhage. Hyperpigmentation was the cardinal feature in 75 (93.8%) while the adrenal crisis was not uncommon. Lack of diagnostic facilities has obscured the etiology in 34 (42.5%) patients.

Conclusions
PAI is not uncommon in Sudanese children where genetic causes outweigh the autoimmune ones. Many cases were missed due to nonspecific presentation, lack of awareness, and difficult access to tertiary health care facilities. In addition to the clinical findings, early morning cortisol ± ACTH levels can be used in diagnosis where facilities are limited particularly synacthen stimulation test.
Overtrusting robots: Setting a research agenda to mitigate overtrust in automation
Authors: Aroyo Alexander M. , de Bruyne Jan , Dheu Orian , Fosch-Villaronga Eduard , Gudkov Aleksei , Hoch Holly , Jones Steve , Lutz Christoph , Sætra Henrik , Solberg Mads , Tamò-Larrieux Aurelia 
Published: October 2021

AbstractThere is increasing attention given to the concept of trustworthiness for artificial intelligence and robotics. However, trust is highly context-dependent, varies among cultures, and requires reflection on others’ trustworthiness, appraising whether there is enough evidence to conclude that these agents deserve to be trusted. Moreover, little research exists on what happens when too much trust is placed in robots and autonomous systems. Conceptual clarity and a shared framework for approaching overtrust are missing. In this contribution, we offer an overview of pressing topics in the context of overtrust and robots and autonomous systems. Our review mobilizes insights solicited from in-depth conversations from a multidisciplinary workshop on the subject of trust in human–robot interaction (HRI), held at a leading robotics conference in 2020. A broad range of participants brought in their expertise, allowing the formulation of a forward-looking research agenda on overtrust and automation biases in robotics and autonomous systems. Key points include the need for multidisciplinary understandings that are situated in an eco-system perspective, the consideration of adjacent concepts such as deception and anthropomorphization, a connection to ongoing legal discussions through the topic of liability, and a socially embedded understanding of overtrust in education and literacy matters. The article integrates diverse literature and provides a ground for common understanding for overtrust in the context of HRI.
Semiotic analysis of symbolic logic using tagmemic theory: with implications for analytic philosophy
Authors: Poythress Vern S. 
Published: October 2021

Abstract
This article uses tagmemic theory as a semiotic framework to analyze symbolic logic. It attends particularly to the issue of context for meaning and the role of personal observer/participants. It focuses on formal languages, which employ no ordinary words and from one point of view have “no meaning.” Attention to the context and the theorists who deploy these languages shows that formal languages have meanings at a higher level, colored by the purposes of the analysts. In fact, there is an indefinitely ascending hierarchy of theories of theories, each of which analyzes and evaluates the theories at a lower level. By analogy with Kurt Gödel’s incompleteness theory, no level of the hierarchy can capture within formalism everything in a sufficiently complex system. The personal analysts always have to make judgments about how a formalized system is analogous to the world outside the system. Arguments in analytic philosophy can be useful in clarification, but neither clarification of terms nor clarification of the structure of arguments can eliminate the need for personal judgment.
The effects of vitamin D, fish oil and exercise on cardiovascular parameters in ovariectomized rats
Authors: Hazar Hale Uyar , Hazar Fatih , Büyüköztürk Karul Aslıhan , Demirci Buket 
Published: October 2021

Abstract

Objectives
This study compared effects of vitamin D, fish oil and exercise on cardiovascular parameters in ovariectomized rats.

Materials and methods
This is an experimental study conducted with 45 female Wistar Albino rats; consisted of one sham (n=8) and four intervention (n=37) groups. Rats (n=37) were oophorectomized and, randomly divided into four groups at the end of the first week following wound healing. Interventions were applied to the groups of oophorectomize+Dvit, oophorectomize+fish oil and oophorectomize+exercise for 12 weeks. In analyzing the data, ANOVA and Tamhane’s T2 tests were used (p<0.05).

Results
The levels of total-cholesterol (66.7 ± 7.6 mg/dL), HDL-cholesterol (33.8 ± 2.1 mg/dL), TOS (7.3 ± 1.2 μmol H2O2 Eq/L), TAS (4.0 ± 0.5 mmol Trolox Eq/L), OSI (0.2 ± 0.1) and total-cholesterol/HDL-cholesterol (2.0 ± 0.3) were obtained significant in exercising oophorectomized rats according to the oophorectomized rats (p<0.05). The estrogen levels of rats using vitamin D and fish oil and exercising were found to be higher than those in menopause.

Conclusions
It was concluded that exercising oophorectomized rats had a lower risk of cardiovascular disease. In this context, exercise/physical activity should be recommended and must be supported for practicing in order to protect the cardiovascular health of postmenopausal women.
A comprehensive review on the development of probiotic supplemented confectioneries
Authors: Şenöztop Eylül , Dokuzlu Tuğçe , Güngörmüşler Mine 
Published: October 2021

Abstract
Probiotics are living organisms that have beneficial effects on host by regulating the microbial balance of the intestinal system. While probiotics are naturally found in yogurt and other fermented foods, they can also be added to many products. Although mostly in dairy products, it is possible to see examples of food products supplemented by probiotics in bakeries, chocolates and confectioneries. Nowadays, the COVID-19 pandemic that the world suffers increased the demand for such functional food products including probiotics. Due to probiotics having potential effects on strengthening the immune system, confectioneries supplemented by probiotics were comprehensively discussed in this review together with the suggestion of a novel gelly composition. The suggested formulation of the product is a gel-like snack contains natural ingredients such as carrot, lemon juice and sugar provided from apples. This research review article provided a guide together with the recommendations for potential probiotic research in candy and confectionery industry.
Administración concursal y cuestiones laborales de la insolvencia a raíz del Real Decreto Legislativo 1/2020, de 5 de mayo, por el que se aprueba el texto refundido de la Ley Concursal
Authors: Gilo Gómez César 
Published: October 2021

Inherente a los concursos de acreedores son las situaciones laborales que el propio funcionamiento de la actividad empresarial del concursado suscita. En este sentido, la correcta gestión del capital humano del deudor se convierte en una cuestión esencial de todo procedimiento concursal, tanto si se alcanza un convenio como si la solución es liquidativa, responsabilidad que recae en gran medida en el órgano de la Administración Concursal a partir de su nombramiento a raíz de la declaración de insolvencia del deudor, órgano que se verá obligado a adoptar importantes decisiones en un escenario inestable por definición.
El Real Decreto Legislativo 1/2020, de 5 de mayo, por el que se aprueba el texto refundido de la Ley Concursal ratifica la importancia del órgano concursal en la aportación de soluciones a las situaciones laborales que se producen en el seno de todo procedimiento concursal.
Level of education, background and clinical stage as prognostic factors according RMST function in patients with early and locally advanced breast cancer: a single institution experience from Romania
Authors: Niță Irina , Nițipir Cornelia , Toma Ștefania Andreea , Limbău Alexandra Maria , Pirvu Edvina , Bădărău Ioana Anca , Suciu Ioana , Suciu George , Manolescu Loredana Sabina Cornelia 
Published: October 2021

Background and aims. Our aim is to examine the relationship between the level of education, background, tumor size and lymph node status on the treatment outcome in a group of patients with early and locally advanced breast cancer (BC) by using the restricted mean survival time (RMST), which summarizes treatment effects in terms of event-free time over a fixed period of time.
Methods. We evaluated the prognostic values in 143 patients treated for early BC at Elias University Emergency Hospital, Bucharest, Romania and followed up for a maximum of 36 months. The protocol was amended to include the levels of education (gymnasium, high school, or university), the background (urban or rural) and the clinical stage (primary tumor (T) and regional nodes (N)). The methodology consisted in using a Kaplan–Meier analysis and RMST for the entire sample and Cox regression, for the variables with statistical influence. The principal endpoints of the study were overall survival (OS) and progression free survival (PFS).
Results. The level of education had impact both on RMST OS (35.30 vs. 26.70) and death HR (hazard ratio) in the group of patients with general school level, compared with those with graduated university. In this study, the urban or rural background did not impact the outcome, probably because in this study we included predominantly patients from urban areas (83%). Although clinical tumor size measurements did not impact the outcome, the clinical staged lymph node influenced both OS (p=0.0500) and PFS (p=0.0006) for the patients with palpable or imaging proof of lymph node involvement of station 2 or 3.
Conclusions. RMST provides an intuitive and explicit way to express the effect of those risk factors on OS and PFS in a cohort of early breast cancer patients. Low level of education and high-grade clinical lymph node status negatively influences the outcome of this cohort of BC patients.
Combined conservative treatment of a recurrent mandibular keratocyst by enucleation, diode laser, 5-Fluorouracil and dental implants: a case report with 18 years-follow up
Authors: Berberi Antoine , Aoun Georges , Hjeij Bouchra , AboulHosn Maissa 
Published: October 2021

In 2017, the World Health Organization classified the odontogenic keratocyst as a developmental odontogenic cyst. The posterior parts of the mandible, especially the angle and the ramus, are the most involved sites. Due to their high recurrence rate, keratocysts are managed surgically with careful complete excision. Additionally, chemical solutions such as Carnoy's solution, modified Carnoy's solution, and 5-Fluorouracil have been associated with surgical treatment.
Diode lasers generate diverse wavelengths that have photothermal and photochemical special properties and could have some effects on the lining epithelium remnants of the cyst.
In this paper, we discuss a case of mandibular recurrent odontogenic keratocyst treated with 5-Fluorouracil topical application after enucleation and diode laser application with 18 years follow-up and teeth replacement with dental implant.
5-Fluorouracil and diode laser have been found to be very effective in the treatment of keratocysts.
On Reason and the Power of Life (Tolstoy contra Spinoza)
Authors: Klimova Svetlana 
Published: October 2021

In his search for the meaning of life, Tolstoy turned to Spinoza’s rationalist teaching about freedom, reason, morality, and religious faith. Spinoza created a philosophy where beliefs are in union with deeds, logic unites with ethics, and knowledge joins faith. According to Tolstoy, it is art that makes a synthesis of all the best attempts of the real, true philosophy. I argue that Tolstoy’s artistic method of linkage (stseplenie) was probably borrowed from Spinoza. Inspired by Spinoza’s “theorems of reason,” Tolstoy created his own “axiom of life” and elaborates on the concept of the “power of life” as a core of religious faith. Tolstoy endorsed Spinoza’s rationalistic critique of religion which helped to liberate true faith from the power of superstition and church dogmatics, but he criticised the geometric form in which Spinoza put the truths he discovered.
The Dialogue Between Believers and Atheists: the Platonic Model in the Laws
Authors: Baliukonis Simonas 
Published: October 2021

This paper examines the question concerning the right model of epistemically rational dialogue. First of all, the main, though not undisputed, principles of rational dialogue are defined according to the contemporary field of the epistemology of disagreement. It then explains why even these principles are not sufficient for making the disagreement between believers and atheists not only a rational discourse but also a fruitful dialogue. This paper defends a thesis that the latter aim can be achieved with a proper model of dialogue, which is found in Plato’s Laws – one of the first discussions between the believers and the atheists in the Western intellectual tradition. This model not only includes the contemporary principles of rational argument but also provides some new guidelines for the solution of problems that lead the believers and the atheists to the communicational dead end.