bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neutral model-based interfacing of 3D design to support collaborative project management in the process plant industry
Authors: Lee Hyunoh , Noh Chiho , Kim Seyun , Kim Byung Chul , Park Jinpyo , Mun Duhwan , Han Soonhung 
Published: March 2021

Abstract
The three-dimensional (3D) design data employed in a process plant construction project are generated during both the basic design and detailed design stages and are used for various purposes throughout the life cycle of the project. After the design stage, 3D design data are converted to a lightweight 3D format and utilized to support procurement, construction, and audit work in a collaborative project management system. However, significant time and cost are incurred when separate interfaces to convert design data are developed for each plant 3D computer-aided design (CAD) system. As an alternative, a method exists to integrate an interface using a neutral model. After translating the 3D input design data for the plant 3D CAD system to a neutral format, this study proposes an interface for use in collaborative project management by converting the data into a lightweight 3D model. In addition, detailed techniques for implementing the proposed interface are described. To verify the validity of the proposed neutral model-based 3D design data interface, translation, inspection, and lightweighting experiments are performed using 3D design data for a synthesized natural gas production plant project.
Preoperative psychogenic fever: to operate or not to operate
Authors: Koren Sondre F , Engel Lilan E , Møller Michael P 
Published: March 2021

Abstract
Postponing elective surgery because of fever on the morning of the operation is frustrating for patients as well as doctors. It is also not cost effective and the unused operation capacity could have been used on other patients. On the other hand, surgery and general anaesthesia will put unwanted physiological strain on a patient fighting an on-going infection. Preoperative fever therefore poses a dilemma; to proceed with-, or to postpone the scheduled operation.
We report a case where a 58-year-old woman, scheduled for prophylactic bilateral mastectomy and primary implant-based reconstruction, was postponed because of a temperature of 37.9°C. The morning of her new operation date, she developed a fever of 39.2°C which fell to 38.2°C shortly after administration of 0.25 mg triazolam. She was diagnosed with psychogenic fever, and we went through with the operation, even though the patient was febrile. The operation was successful, and she had no post-operative complications.
Using MALDI-ToF mass spectrometry to identify mushroom species: Proof of concept analysis ofAmanitagenus specimens
Authors: Piarroux Raphael , Gabriel Frédéric , Grenouillet Frédéric , Collombon Patrick , Louasse Philippe , Piarroux Martine , Normand Anne-Cécile 
Published: March 2021

AbstractFood poisoning caused by toxic mushrooms, such as species in the Amanita genus, occurs frequently around the world. To properly treat these patients, it is important to rapidly and accurately identify the causal species. Matrix-assisted laser desorption/ionization time-of-flight (MALDI-ToF) mass spectrometry is a rapid technique that has been used in medical laboratories for the past three decades to identify bacteria, yeasts, and filamentous fungi.Matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-Tof MS) is a rapid method used for the past three decades to identify microorganisms. In this study, we created and internally validated a MALDI-Tof MS reference database comprising 15 Amanita species frequently encountered in France, and we challenged this database with 38 Amanita specimens from four French locations, using a free online application for MALDI-ToF spectra identifications.Assessment of the database showed that mass spectra can be obtained by analyzing any portion of a carpophore and that all portions enabled identification of the carpophore at the species level. Most carpophores were correctly identified using our database, with the exception of specimens from the Vaginatae section. Decay tests also demonstrated that decayed portions (like those found in the kitchen garbage can) of Amanita phalloides mushrooms could be properly identified using MALDI-ToF MS.Our findings provide important insight for toxicology laboratories that often rely on DNA sequencing to identify meal leftovers implicated in food poisoning. In future developments, this technique could also be used to detect counterfeit mushrooms by including other genera in the reference database.Lay SummaryMALDI-ToF MS is a powerful identification tool for microorganisms. We demonstrate that the technique can be applied to Amanita specimens. This will prevent food intoxications as a rapid and definite identification can be obtained, and it can also be used for food remnants.
Modelling the M*–SFR relation at high redshift: untangling factors driving biases in the intrinsic scatter measurement
Authors: Curtis-Lake E , Chevallard J , Charlot S , Sandles L 
Published: March 2021

ABSTRACT
We present a method to self-consistently propagate stellar-mass [$\hbox{$\hbox{${\rm M}$}_{\star }$}=\log (\hbox{${\rm M}$}/\hbox{${\rm M}_{\odot }$})$] and star-formation-rate [$\hbox{${\Psi }$}=\log (\hbox{${\psi }$}/\hbox{${\rm M}_{\odot }$}\, {\rm yr}^{-1}$)] uncertainties on to intercept (α), slope (β), and intrinsic-scatter (σ) estimates for a simple model of the main sequence of star-forming galaxies, where $\hbox{${\Psi }$}= \alpha + \beta \hbox{$\hbox{${\rm M}$}_{\star }$}+ \mathcal {N}(0,\sigma)$. To test this method and compare it with other published methods, we construct mock photometric samples of galaxies at z ∼ 5 based on idealized models combined with broad- and medium-band filters at wavelengths 0.8–5 μm. Adopting simple Ψ estimates based on dust-corrected ultraviolet luminosity can underestimate σ. We find that broad-band fluxes alone cannot constrain the contribution from emission lines, implying that strong priors on the emission-line contribution are required if no medium-band constraints are available. Therefore, at high redshifts, where emission lines contribute a higher fraction of the broad-band flux, photometric fitting is sensitive to Ψ variations on short (∼10 Myr) time-scales. Priors on age imposed with a constant (or rising) star formation history (SFH) do not allow one to investigate a possible dependence of σ on $\hbox{${\rm M}$}_{\star }$ at high redshifts. Delayed exponential SFHs have less constrained priors, but do not account for Ψ variations on short time-scales, a problem if σ increases due to stochasticity of star formation. A simple SFH with current star formation decoupled from the previous history is appropriate. We show that, for simple exposure-time calculations assuming point sources, with low levels of dust, we should be able to obtain unbiased estimates of the main sequence down to $\mathrm{ log}(\hbox{${\rm M}$}/\hbox{${\rm M}_{\odot }$})\sim 8$ at z ∼ 5 with the James Webb Space Telescope while allowing for stochasticity of star formation.
Galactic seismology: the evolving ‘phase spiral’ after the Sagittarius dwarf impact
Authors: Bland-Hawthorn Joss , Tepper-García Thor 
Published: March 2021

ABSTRACT
In 2018, the ESA Gaia satellite discovered a remarkable spiral pattern (‘phase spiral’) in the z − Vz phase plane throughout the solar neighbourhood, where z and Vz are the displacement and velocity of a star perpendicular to the Galactic disc. In response to Binney & Schönrich’s analytic model of a disc-crossing satellite to explain the Gaia data, we carry out a high-resolution, N-body simulation (N  ≈ 108 particles) of an impulsive mass (2 × 1010 M⊙) that interacts with a cold stellar disc at a single transit point. The disc response is complex since the impulse triggers a superposition of two distinct bisymmetric (m = 2) modes − a density wave and a corrugated bending wave − that wrap up at different rates. Stars in the faster density wave wrap up with time T according to ϕD(R, T) = (ΩD(R) + Ωo) T, where ϕD describes the spiral pattern and ΩD = Ω(R) − κ(R)/2, where κ is the epicyclic frequency. While the pattern speed Ωo is small, it is non-zero. The slower bending wave wraps up according to ΩB ≈ ΩD/2 producing a corrugated wave. The bunching effect of the density wave triggers the phase spiral as it rolls up and down on the corrugated wave (‘roller coaster’ model). The phase spiral emerges slowly about ΔT ≈ 400 Myr after impact. It appears to be a long-lived, disc-wide phenomenon that continues to evolve over most of the 2 Gyr simulation. Thus, given Sagittarius’ (Sgr) low total mass today (Mtot ∼ 3 × 108 M⊙ within 10 kpc diameter), we believe that the phase spiral was excited by the disc-crossing dwarf some 1–2 Gyr before the recent transit. For this to be true, Sgr must be losing mass at 0.5–1 dex per orbit loop.
Linear systematics mitigation in galaxy clustering in the Dark Energy Survey Year 1 Data
Authors: Wagoner Erika L , Rozo Eduardo , Fang Xiao , Crocce Martín , Elvin-Poole Jack , Weaverdyck Noah ,   (DES Collaboration)
Published: March 2021

ABSTRACT
We implement a linear model for mitigating the effect of observing conditions and other sources of contamination in galaxy clustering analyses. Our treatment improves upon the fiducial systematics treatment of the Dark Energy Survey (DES) Year 1 (Y1) cosmology analysis in four crucial ways. Specifically, our treatment (1) does not require decisions as to which observable systematics are significant and which are not, allowing for the possibility of multiple maps adding coherently to give rise to significant bias even if no single map leads to a significant bias by itself, (2) characterizes both the statistical and systematic uncertainty in our mitigation procedure, allowing us to propagate said uncertainties into the reported cosmological constraints, (3) explicitly exploits the full spatial structure of the galaxy density field to differentiate between cosmology-sourced and systematics-sourced fluctuations within the galaxy density field, and (4) is fully automated, and can therefore be trivially applied to any data set. The updated correlation function for the DES Y1 redMaGiC catalogue minimally impacts the cosmological posteriors from that analysis. Encouragingly, our analysis does improve the goodness-of-fit statistic of the DES Y1 3 × 2pt data set (Δχ2 = −6.5 with no additional parameters). This improvement is due in nearly equal parts to both the change in the correlation function and the added statistical and systematic uncertainties associated with our method. We expect the difference in mitigation techniques to become more important in future work as the size of cosmological data sets grows.
Computational meta-analysis of ribosomal RNA fragments: potential targets and interaction mechanisms
Authors: Guan Lingyu , Grigoriev Andrey 
Published: March 2021

Abstract
The most abundant cellular RNA species, ribosomal RNA (rRNA), appears to be a source of massive amounts of non-randomly generated fragments. We found rRNA fragments (rRFs) in immunoprecipitated Argonaute (Ago-IP) complexes in human and mouse cells and in small RNA sequencing datasets. In human Ago1-IP, guanine-rich rRFs were preferentially cut in single-stranded regions of mature rRNAs between pyrimidines and adenosine, and non-randomly paired with cellular transcripts in crosslinked chimeras. Numerous identical rRFs were found in the cytoplasm and nucleus in mouse Ago2-IP. We report specific interaction motifs enriched in rRF-target pairs. Locations of such motifs on rRFs were compatible with the Ago structural features and patterns of the Ago-RNA crosslinking in both species. Strikingly, many of these motifs may bind to double-stranded regions on target RNAs, suggesting a potential pathway for regulating translation by unwinding mRNAs. Occurring on either end of rRFs and matching intronic, untranslated or coding regions in targets, such interaction sites extend the concept of microRNA seed regions. Targeting both borders of certain short introns, rRFs may be involved in their biogenesis or function, facilitated by Ago. Frequently dismissed as noise, rRFs are poised to greatly enrich the known functional spectrum of small RNA regulation.
Incidence, Characteristics and Outcomes of Large Vessel Stroke in COVID-19 Cohort: An International Multicenter Study
Authors: Khandelwal Priyank , Al-Mufti Fawaz , Tiwari Ambooj , Singla Amit , Dmytriw Adam A , Piano Mariangela , Quilici Luca , Pero Guglielmo , Renieri Leonardo , Limbucci Nicola , Martínez-Galdámez Mario , Schüller-Arteaga Miguel , Galván Jorge , Arenillas-Lara Juan Francisco , Hashim Zafar , Nayak Sanjeev , Desousa Keith , Sun Hai , Agarwalla Pankaj K , Nanda Anil , Roychowdhury J Sudipta , Nourollahzadeh Emad , Prakash Tannavi , Gandhi Chirag D , Xavier Andrew R , Lozano J Diego , Gupta Gaurav , Yavagal Dileep R 
Published: March 2021

Abstract

BACKGROUND
While there are reports of acute ischemic stroke (AIS) in coronavirus disease 2019 (COVID-19) patients, the overall incidence of AIS and clinical characteristics of large vessel occlusion (LVO) remain unclear.

OBJECTIVE
To attempt to establish incidence of AIS in COVID-19 patients in an international cohort.

METHODS
A cross-sectional retrospective, multicenter study of consecutive patients admitted with AIS and COVID-19 was undertaken from March 1 to May 1, 2020 at 12 stroke centers from 4 countries. Out of those 12 centers, 9 centers admitted all types of strokes and data from those were used to calculate the incidence rate of AIS. Three centers exclusively transferred LVO stroke (LVOs) patients and were excluded only for the purposes of calculating the incidence of AIS. Detailed data were collected on consecutive LVOs in hospitalized patients who underwent mechanical thrombectomy (MT) across all 12 centers.

RESULTS
Out of 6698 COVID-19 patients admitted to 9 stroke centers, the incidence of stroke was found to be 1.3% (interquartile range [IQR] 0.75%-1.7%). The median age of LVOs patients was 51 yr (IQR 50-75 yr), and in the US centers, African Americans comprised 28% of patients. Out of 66 LVOs, 10 patients (16%) were less than 50 yr of age. Among the LVOs eligible for MT, the average time from symptom onset to presentation was 558 min (IQR 82-695 min). A total of 21 (50%) patients were either discharged to home or discharged to acute rehabilitation facilities.

CONCLUSION
LVO was predominant in patients with AIS and COVID-19 across 2 continents, occurring at a significantly younger age and affecting African Americans disproportionately in the USA.
Recoverability and Expectations-Driven Fluctuations
Authors: Chahrour Ryan , Jurado Kyle 
Published: March 2021

Abstract
Time series methods for identifying structural economic disturbances often require disturbances to satisfy technical conditions that can be inconsistent with economic theory. We propose replacing these conditions with a less restrictive condition called recoverability, which only requires that the disturbances can be inferred from the observable variables. As an application, we show how shifting attention to recoverability makes it possible to construct new identifying restrictions for technological and expectational disturbances. In a vector autoregressive example using post-war U.S. data, these restrictions imply that independent disturbances to expectations about future technology are a major driver of business cycles.
Extracutaneous involvement is common and associated with prolonged disease activity and greater impact in juvenile localized scleroderma
Authors: Li Suzanne C , Higgins Gloria C , Chen Mallory , Torok Kathryn S , Rabinovich C Egla , Stewart Katie  , Laxer Ronald M , Pope Elena , Haines Kathleen A , Punaro Marilynn , O’Neil Kathleen M 
Published: March 2021

Abstract

Objective
The aim of this study was to evaluate factors associated with extracutaneous involvement (ECI) in juvenile localized scleroderma (jLS).

Methods
A prospective, multicentre, 6-month observational study was performed. The data collected included disease features, global assessments, and subject symptoms. Bivariate and linear multilevel regression analyses were performed.

Results
A total of 86 jLS subjects (80% female, 80% Caucasian), median age of disease onset 7.7 years, were evaluated. Most had linear scleroderma or mixed morphea. Of the 86 subjects, 49 (57%) had 125 extracutaneous problems {median 2 [interquartile range (IQR) 1, 3] per subject} from nine organ systems. Most of these subjects had multiple musculoskeletal problems. ECI was associated with more extensive cutaneous involvement, higher number of symptoms, family history of autoimmunity, and ANA and RF positivity. Subjects with ECI had higher scores for physician global assessment of damage (PGA-D), and parental global assessment of disease impact, but not baseline physician global assessment of disease activity (PGA-A). Although subjects with ECI received more MTX and glucocorticoid treatment, they had a slower reduction in PGA-A scores and symptoms over time, suggesting a poorer response to treatment. In logistic regression modelling, female sex had the largest effect on parental impact scores.

Conclusion
ECI occurred in the majority of subjects with jLS, and was associated with more medication use, longer treatment duration, higher PGA-D scores, and higher parental assessment of disease impact. Our findings suggest that jLS subjects with ECI have greater overall disease burden, both cutaneous and extracutaneous, and poorer response to treatment. More study of the treatment needs of this population is warranted.
Liver stiffness is able to differentiate hepatosplenic Schistosomiasis mansoni from liver cirrhosis and spleen stiffness may be a predictor of variceal bleeding in hepatosplenic schistosomiasis
Authors: Silva Catherine F , Nardelli Mateus J , Barbosa Fernanda A , Galizzi Humberto O , Cal Tereza C M F , Ferrari Teresa C A , Faria Luciana C , Couto Claudia A 
Published: March 2021

Abstract

Background
Ultrasonography is limited for differentiating portal hypertension due to liver cirrhosis from that secondary to hepatosplenic schistosomiasis (HSS). We aimed to investigate the role of transient elastography (TE) in differentiating HSS mansoni from cirrhosis and the factors associated with liver and spleen stiffness (LS and SS) in HSS.

Method
A cross-sectional study was conducted including patients with HSS mansoni (n=29) and liver cirrhosis due to non-alcoholic steatohepatitis (n=23). All patients underwent TE and those with HSS were assessed by the Niamey protocol.

Results
HSS subjects presented lower median LS (9.6 vs 21.3 Kpa, p&lt;0.001) and liver controlled attenuation parameter (229 vs 274 dB/m, p=0.010) than cirrhosis subjects, in addition to higher SS (73.5 vs 42.2 Kpa, p=0.002). The area under the receiver operating characteristic curve for detecting cirrhosis by LS was 0.947 (95% CI 0.89 to 1.00, p&lt;0.001), with an optimal cut-off of 11.75 Kpa. In HSS subjects, higher SS was associated with the presence of the following: diabetes mellitus (p=0.036), metabolic syndrome (p=0.043), esophageal varices (p=0.001), portal vein thrombosis (p=0.047) and previous variceal bleeding (p=0.011). In HSS patients without portal vein thrombosis, variceal bleeding was associated with higher SS (p=0.018). Niamey categories were not associated with LS (p=0.676) or SS (p=0.504).

Conclusion
TE can play a role in differentiating HSS from cirrhosis, especially by LS. SS may be further investigated for predicting complications in HSS.
Beliefs about Mask Efficacy and the Effect of Social Norms on Mask Wearing Intentions for COVID-19 Risk Reduction
Authors: Bokemper Scott E. , Cucciniello Maria , Rotesi Tiziano , Pin Paolo , Malik Amyn A. , Willebrand Kathryn , Paintsil Elliott E. , Omer Saad B. , Huber Gregory A. , Melegaro Alessia 
Published: March 2021

AbstractIn the absence of widespread vaccination for COVID-19, governments and public health officials have advocated for the public to wear masks during the pandemic. The decision to wear a mask in public is likely affected by both beliefs about its efficacy and the prevalence of the behavior. Greater mask use in the community may encourage others to follow this norm, but it also creates an incentive for individuals to free ride on the protection afforded to them by others. We report the results of two vignette-based experiments conducted in the United States and Italy to examine the causal relationship between beliefs, social norms, and reported intentions to engage in mask promoting behavior. We find that providing factual information about how masks protect others increases the likelihood that someone would wear a mask or encourage others to do so in the United States, but not in Italy. There is no effect of providing information about how masks protect the wearer in either country. Additionally, greater mask use increases intentions to wear a mask and encourage someone else to wear theirs properly in both the United States and Italy. Thus, community mask use may be self-reinforcing.
Apparent growth paradox ofStaphylococcus epidermidisin response to extremely low frequency electromagnetic radiation exposure
Authors: Malik Dyaan , Pineda Esmeralda , Zambrana Deyvis Mejia 
Published: March 2021

AbstractStaphylococcus epidermidisis a normal part of the human microbiome; however, it is an opportunistic pathogen and can cause infections when the delicate balance of this microbiome is disrupted. Furthermore, infections caused by this bacterium can be hard to treat as a result of antibiotic resistance and biofilm production. This experiment aimed to determine whether electromagnetic field radiation (ELF-EMF) could be a deterrent of bacterial growth, as an alternative treatment to antibiotics. A non-pathogenic strain ofS. epidermidiswas used for experimentation, which took place in a school laboratory setting. The experimental group was exposed to ELF-EMF, while the control group did not receive the ELF-EMF treatment. The number of bacterial colonies, represented as colony forming units (CFUs) and area of random colonies were calculated to determine the effect of this treatment. There was no dramatic difference of colony formation on days 0, 1, and 2 of the four day period of ELF-EMF exposure. However, colony formation for days 3 and 4 showed a significant difference between the control and the experimental groups, as the experimental group had a significantly higher CFU count than the control. The average CFU count for day 3 in the control group was 420.6 and 1,097.4 for the experimental group (p<0.0001, t=12.9803). On the final day of the experimentation (Day 4) the average CFU count for the control group was 424.6 and 896.4 for the experimental group (p<0.0001, t=5.8926). The area for five randomly chosen colonies from each petri dish was calculated on the fourth day of experimentation. The area for the experimental group was significantly lower than that control (p<0.0001, with t=6.8659). The average area for the control group was 1.3249 mm2and a lower average of 0.6375mm2for the experimental group. These results demonstrate that the ELF-EMF treatment had an inhibitory effect on the area growth ofS. epidermidis, but not on the colony-forming ability of S. epidermidis. This suggests that ELF-EMF influences the means by which the bacteriumS. epidermidisgrows.