bluuebunny/crossref_metadata_2025_split huggingface dataset:
Features of cascading disk-gear extrusion of plastics
Authors: Kovba Anastasiia , Shved Mykola , Shved Dmytro 
Published: October 2021

The relevant task of today is to improve the installations for thermostat extrusion, in order to increase the indicators of resource/energy efficiency. The study of the features peculiar to the loading and melting area (LMA) and the elimination of shortcomings can significantly reduce the energy costs of the process.
To achieve high-quality results in cascading disk-gear extrusion, the main methods of the dispersion melting of thermoplastic granules are analyzed, taking into account all the features of the physical model of the extrusion process.
The dispersion model of melting is achieved by observing a limited supply of raw materials to the loading area. This ensures the intensification of the process and significantly reduces the total length of the LMA. In this case, the length of the area with the most filled channel directly depends on the resistance of the disk zone. With increasing resistance, the polymer stopper moves to the loading neck. The polymer is gradually compacted, and each leakage of the LMA is periodically filled.
From the rotating disk heated to 107 oC, samples of the polymer were removed and cut into separate sections. Previously, to facilitate the process of visual research, the polymer was colored with 0.5% blue pigment. The results of the analysis confirmed the performance of the proposed physical model for the processes occuring in the disk-gear extruder. As a result, it is possible to calculate the time over which the granules stay in the LMA and the length of the screw cutting in this area, depending on the performance.
Taking into account all the features of the disk-gear extrusion process allows creating an upgraded productive, resource-efficient installation and implementing it into practice.
Galinheiro Pedagógico: um espaço de alfabetização científica no Clube de Ciências
Authors: Silveira da Rosa Sabrina , Moreira Rodrigues Andressa Luana , Lima Robaina José Vicente 
Published: October 2021

Este artigo teve como objetivo verificar se as atividades desenvolvidas no Clube de Ciências a partir da realidade dos educandos contribuíram para uma aprendizagem significativa dos alunos do 3°, 4° e 5° anos de uma escola do/no campo. Para realização desta pesquisa foram elaboradas oito atividades, em dois meses que envolveu a construção de um galinheiro, evolução da terra e estudo sobre as galinhas. Para levantamento dos dados foi realizado a construção de um livro com os conteúdos estudados. Na análise dos dados se utilizou da Análise Textual Discursiva. Concluiu-se que a Educação em Ciências na escola do/no campo, partindo da realidade dos estudantes através do Clube de Ciências, potencializaram uma aprendizagem significativa.
Palavras-chave: popularização da ciência, aprendizagem significativa, clube de ciências, educação do campo.

Pedagogical chicken: a space for scientific literacy in the science club
ABSTRACT. This article aimed to verify if the activities developed in the Science Club based on the reality of the students contributed to a significant learning of the students of the 3rd, 4th and 5th years of a school in the countryside. In order to carry out this research, eight activities were carried out in two months, which involved the construction of a chicken coop, the evolution of the land and a study on the hens. To collect the data, a book with the studied contents was built. In the analysis of the data it was used the Discursive Textual Analysis where it was concluded that the Science Education in the school of/in the countryside, starting from the reality of the students through the Science Club, potentiated a significant learning.
Keywords: popularization of science, meaningful learning, countryside science, and rural education.

Gallinero pedagógico: un espacio de alfabetización científica en el club de ciencias
RESUMEN. Este artículo tuvo como objetivo verificar si las actividades desarrolladas en el Club de Ciencias a partir de la realidad de los alumnos contribuyeron a un aprendizaje significativo de los alumnos de 3º, 4º y 5º curso de una escuela en el campo. Para la realización de esta investigación se elaboraron ocho actividades, en dos meses, que involucraron la construcción de un gallinero, evolución de la Tierra y estudio de las gallinas. Para la recogida de datos se construyó un libro con los contenidos estudiados. En el análisis de los datos se utilizó el Análisis Textual Discursivo donde se concluyó que la Educación Científica en la escuela de/en el campo, a partir de la realidad de los estudiantes a través del Club de Ciencias, potenció un aprendizaje significativo.
Palabras clave: popularización de la ciencia, aprendizaje significativa, club de ciencia, educación rural.
Uma caminhada da Psicologia com a Educação do Campo: entrevista com Maria Isabel Antunes-Rocha
Authors: Ribeiro Luiz Paulo 
Published: October 2021

Maria Isabel Antunes-Rocha é professora titular do Departamento de Ciências Aplicadas à Educação (DECAE) da Faculdade de Educação da Universidade Federal de Minas Gerais (UFMG), Brasil. Ela se graduou em Psicologia pela UFMG (1983), fez mestrado em Psicologia e doutorado em Educação. Realizou dois estágios pós-doutorais: um na Universidade Estadual Paulista Júlio Mesquita Filho (UNESP), desenvolvendo estudos sobre Territorialidades, e um na Pontifícia Universidade Católica de São Paulo (PUC São Paulo) sobre Representações Sociais. Como professora da UFMG desde 1995, ela atua em cursos de formação de professores, mantendo sua referência na Psicologia Social e direcionando olhares e ações aos movimentos sociais e sindicais campesinos. Nesse envolvimento, em atenção às demandas desses movimentos por educação e vislumbrando o compromisso social das universidades públicas brasileiras, Maria Isabel colaborou intensamente na execução da primeira turma de formação de professores para atuar em escolas do campo, em 2004, e participou, em 2008, da oferta piloto, juntamente com a Universidade de Brasília (UNB), Universidade Federal de Sergipe (UFS) e Universidade Federal da Bahia (UFBA), de cursos de Licenciatura em Educação do Campo. Desde então, sua relação e contribuição com a área da Educação do Campo e da formação de professores para atuar nas escolas do campo é extensa e com muitas repercussões. Assim, esta entrevista foi feita para entender, através da história profissional da professora Maria Isabel, formas de aproximação da psicologia com as populações do campo no Brasil e, em específico, as correlações entre a psicologia e o campesinato.
Atuação da Auditoria Interna nas Universidades Federais Brasileiras
Authors: Rodrigues Rubens Carlos , Veras Machado Marcus Vinicius 
Published: October 2021

Objetivo do trabalho:
Analisar as atividades desenvolvidas, no âmbito das universidades públicas federais brasileiras, do ponto de vista da própria unidade.

Metodologia:
Esta pesquisa, do tipo censitária, possui natureza qualitativa e descritiva, utilizando-se de análise documental dos dados obtidos através da Lei de Acesso a Informações, do Plano Anual de Atividades de Auditoria Interna e Relatório Anual de Atividades de Auditoria Interna, organizados e tabulados por meio do software Excel®.

Resultados:
Nas 63 universidades federais pesquisadas foram planejadas 1.052 atividades e os resultados obtidos demonstram que as atividades desenvolvidas visam os Controles da Gestão e possuem como foco, principalmente, as auditorias de gestão e operacional. Mais de um terço das atividades desenvolvidas estão ligadas ao assessoramento a gestores, acompanhamento da implementação de recomendações dos órgãos de controle e emissão de relatórios, demonstrando a proatividade deste departamento com a gestão.

Originalidade:
Busca evidenciar as práticas deste órgão, mesmo que focada em seus componentes, em um ambiente que envolve grandes volumes financeiros e impactam no desenvolvimento da sociedade e produção de conhecimento.

Contribuições teóricas e práticas:
Comprova que o foco dos trabalhos desenvolvidos pela Auditoria Interna moderna não consiste somente em avaliar os controles internos, mas todo o processo de gestão de riscos e governança da entidade no intuito de atender as necessidades da organização e assessorá-la, conforme prevê a literatura acadêmica e normativa.
Molecular profile to cancer cell line matchmaking
Authors: Reardon Brendan , Allen Eliezer Van 
Published: October 2021

Abstract
Profile-to-cell line matchmaking is a computational protocol to identify cancer cell lines that are genomically similar to a patient’s case profile. In doing so, high-throughput drug screens applied to the same cancer cell lines may be used for therapeutic hypothesis generation in research settings and potentially in clinical settings. To evaluate the metrics of the matchmaking, a hold-one-out approach of the considered cancer cell lines is applied, and molecular similarity models are assessed based on their ability to identify cancer cell lines that share therapeutic sensitivity.
Straw Checkerboard Barriers Improve Soil Characteristic and Growth Performance of Winter Cover Crops and Protect Sloping Land
Authors: Dehkordi Elahe Ahmadpoor , Surki Ali Abbasi , Pajouhesh Mehdi , Tahmasebi Pejman 
Published: October 2021

Abstract
Aims Finding how straw checkerboard barrier technology, as a sustainable and environment-friendly method, may affect soil chemical properties and water status despite wind erosion control directed us to evaluate this technique as a vital component of management plans in sloping lands of semi-arid areas. We were interested to know if it could support the soil capabilities to grow pilot plants and recover some ecological services via alleviate drought stress or amendment of soil attributes.Methods In order to study soil characteristic and growth performance of winter cover crops, an experiment was carried out in 2018. Checkerboards were setup in a 1×1 m pattern with rice residues. Seeds of sainfoin (Onobrychis sativa), rye (Secale montanum) and tall wheatgrass (Agropyron sp) were sown at the checkerboards and bare ground as the control. Detailed analyses include growth characteristics, physiological attributes i.e. photosynthetic pigment contents, proline and malondialdehyde contents and relative water contents of mentioned crops and the related soil properties during the growing season were carried out in borders and centers of the straw checkerboards and bare ground.Results Soil covered with straw checkerboard barriers was the most effective for improving vegetation growth and establishing taller plants with higher biomass. Based on the physiological analyses, the rye grown in straw checkerboard plots coped well with dry conditions. Higher proline content and more efficient osmotic adjustment indicates improvements of soil water retention status, which may alleviate drought stress damages and improve cover crop performance in straw checkerboard plots. Photosynthetic pigments also showed higher contents in checkerboards for rye. Soil organic matter, total nitrogen, available phosphorus, potassium and water storage increased in checkerboards too, however, such effects vary with the crop type. Conclusions straw checkerboards could be deemed as an effective management strategy in semi-arid areas, as an important method for conserving natural resources and sustaining productivity.
The Role of Growth Hormone and IGF-1 in Retinopathy: A Prospective Study of Retinopathy in Patients with Acromegaly and Impaired Fasting Glucose
Authors: Wu Tzu-En , Chen Harn-Shen 
Published: October 2021

Abstract
Aims
To investigate the effects of the GH-IGF-1 axis on the incidence and progression of retinopathy.
Methods
We enrolled 91 patients with acromegaly and 123 subjects with impaired fasting glucose (IFG) between 2008 and 2016 to examine the incidence and prevalence of retinopathy. Patients attended follow-ups in our clinics and underwent examinations according to the national guidelines for diabetes management. Both cohorts attended follow-ups until June 2019.
Results
Both groups had similar HbA1c, cholesterol, and blood pressure levels. However, patients with acromegaly had higher GH (8.05±16.18 vs. 0.78±1.25 ng/mL) and IGF-1 (547.0±342.1 vs. 146.7±51.4 ng/mL) levels than in subjects with IFG. During the follow-up period, eight patients (8.8%) with acromegaly and 12 patients (9.8%) with IFG developed some degree of retinopathy. Three patients with acromegaly and two with IFG progressed to proliferative retinopathy. Patients with acromegaly had the same incidence of non-proliferative retinopathy (odds ratio [OR]: 0.830; 95% CI: 0.318–2.164) and a non-statistically significantly higher incidence of proliferative retinopathy (OR: 2.461; 95% CI: 0.404–14.988).
Conclusion
The data reveals that GH and IGF-1 might play a crucial role in the development of proliferative retinopathy and influence its progression. Therefore, we suggest screening patients with acromegaly should be similar to diabetes patients.
A Nested Qualitative Evaluation of User Experiences in a Randomized Trial of a Digital Intervention To Support Total-Skin-Self-Examination By Melanoma Survivors
Authors: Reilly Felicity , Wani Nuha , Hall Susan , Morgan Heather , Allan Julia , Murchie Peter , Constable Lynda 
Published: October 2021

Abstract
BackgroundMelanoma is a common cancer with a high survival rate, as well as a high chance of recurrence. Combined, this leads to a high burden of follow-up. Total-Skin-Self-Examination (TSSE) improves clinical outcomes of melanoma via early detection of new primaries and recurrences, and technology is an increasingly popular means of facilitating TSSE. Thus, the Achieving Self-directed Integrated Cancer Aftercare (ASICA) digital healthcare intervention was developed. Embedded within a randomised control trial (RCT), this nested study used qualitative interviews to explore in depth participants’ experiences of TSSE, their orientation toward technology and both participant and professionals’ practical and technical experiences of the ASICA intervention.MethodsSemi-structured telephone interviews were undertaken during the RCT with participants and the coordinating Dermatology Nurse Practitioner (DNP). Participants were purposively sampled to achieve a representative sample. Interviews were transcribed verbatim and analysed using a Framework Analysis approach applied within NVivo12.ResultsTwenty-two interviews were completed with participants and one with the coordinating DNP. ASICA appeared to change participants’ perceptions of skin checking: users were more likely to report routinely performing TSSE thoroughly. There was some variation in beliefs about skin-checking and using technology for healthcare generally. Overall, ASICA was experienced positively by participants and the DNP. Several clear practical suggestions were made for how ASICA can be improved.ConclusionThe ASICA app appears to have positively influenced the attitudes and TSSE practices of melanoma survivors. Technical improvements are required, but the app offers promise for technologically enhanced melanoma follow-up in future.Trial RegistrationClinical Trials.gov, NCT03328247. Registered on 1 November 2017 - https://clinicaltrials.gov/ct2/show/NCT03328247?term=ASICA&rank=1
Multiple Factors Mediate Insecticide Toxicity To A Key Predator For Cotton Insect Pest Management
Authors: Potin Denner Manthay , Machado Anderson Vinnicius Arruda , Barbosa Paulo Roberto Ramos , Torres Jorge Braz 
Published: October 2021

Abstract
Mortality of agricultural pests caused by arthropod predators is a valuable ecosystem service for crop production. The earwig, Euborellia annulipes (Lucas), attacks different pest species in various crop ecosystems, including larvae and pupae of the boll weevil, Anthonomus grandis grandis (Boh.). Despite such biological control, cotton pest management remains heavily dependent on synthetic insecticides. In this study, multiple factors were assessed to measure the selectivity of insecticides used against sap-sucking and chewing cotton pests for two E. annulipes populations. Nymphs and adults of E. annulipes were exposed to the insecticides in two ways: ingestion of contaminated prey, and contact with dried residues on either inert surfaces or treated plants bearing prey. Pymetrozine, chlorantraniliprole, and spinetoram had little effect on the predator regardless the tested earwig population, life stage, or the route of exposure. Cyantraniliprole affected the predator in some life stages and through some types of contact. Pyriproxyfen was harmless to adult earwigs, but prevented normal development of nymphs to adults. Chlorfenapyr, indoxacarb, lambda-cyhalothrin, chlorpyrifos, dimethoate, and malathion were harmful to the predator regardless earwig life stage or method of exposure. The negative impact was diminished when exposure occurred on plants with predator allowed to shelter in the soil. The results indicate that insecticide selectivity outcome is a multi-factor driven by the insecticide, predator life stage and the redator’s behavior. Therefore, testing different predator life stages via several routes of exposure, without denying the insect the opportunity to engage in its normal behaviors can provide better estimates of insecticide selectivity.
High TROAP Expression Correlates With Shorter Survival in Patients With Glioma: A Study Based on Multiple Data Fusion Analysis
Authors: Liu Zhendong , Liu Runze , Cheng Xingbo , Lian Xiaoyu , Zhu Yongjie , Ren Zhishuai , Liu Binfeng , Gao Yanzheng 
Published: October 2021

Abstract
Trophinin-associated protein (TROAP) was originally identified to mediate the embryo transfer process and participate in the regulation of microtubules but was later found to be associated with the biological behavior of various types of cancers. However, there is limited information about the role of TROAP in glioma. In this study, thousands of glioma samples were obtained from multiple independent datasets to detect changes in TROAP mRNA and protein expression levels in glioma, we found that compared with normal brain tissues, the expression of TROAP in glioma was significantly increased at both levels. Then, the correlations between TROAP and clinical characteristics and prognosis in glioma were revealed through a series of bioinformatics analysis methods. The overexpression of TROAP was an independent risk factor for glioma and was associated with a reduced overall survival rate of glioma patients. In addition, TROAP had value for determining the prognosis of patients, especially patients with WHO grade III glioma. Quantitative reverse transcription polymerase chain reaction (RT-qPCR) was used to verify the expression level of TROAP in glioma cell lines. Subsequently, GSEA identified homologous recombination, cell cycle and p53 signalling pathways as differentially enriched with the high TROAP expression phenotype. Finally, four drugs that may inhibit TROAP expression and have potential therapeutic value for glioma were screened out through CMap website: bezafibrate, clobetasol, scriptaid, and thioguanosine. In conclusion, TROAP, as a new oncogene, leads to poor prognosis of glioma patients, and as a highly specific biomarker, provides the possibility for individual clinical treatment of glioma patients.
What Is the Relationship Between the Breech Presentation and Femoral Trochlear Dysplasia? An Experimental Study of the Breech Presentation Model in Neonatal Rats
Authors: Li Weifeng , Wang Shengjie , Tang Shiyu , Dong Zhenyue , Wang Fei 
Published: October 2021

Abstract
Background: The relationship between breech presentation and trochlear dysplasia had been confirmed. However, the pathological process of breech-related trochlear dysplasia remain unclear. This study aimed to establish an animal model to simulate breech presentation and to analyze the pathological process of the femoral trochlea.Materials and Methods: One hundred and twenty neonatal rats were randomly assigned into a control group and two experimental groups that were swaddled (using surgical tape) to keep the hip flexed and knees extended to simulate human breech presentation for the 5 days (short Swaddling) and the 10 days (prolonged Swaddling) of life. Gross and cross-sectional observation, histological staining measurement in two experimental time points (5, 10 days after birth) were conducted to evaluate the morphological changes of the femoral trochlea.Results: The incidence of trochlear dysplasia increased with the Swaddling time. Rats in the prolonged Swaddling group had the high prevalence of trochlea dysplasia (52 of 60), followed by short Swaddling group (42 of 60). Gross and cross-sectional observation showed a shallower trochlea groove in two experimental groups. Histologicalstaining measurement indicated that the trochlear sulcus angle and trochlear sulcus depth were significantly different between the experimental group and the control group since day 5 and day 10. Conclusion: In this model, breech presentation had a adverse influence on neonatal knees and could induce trochlear dysplasia. What is more, this study also showed that the more time in breech presentation, the more incidence of trochlear dysplasia.
Spatio-Temporal Changes in Ecology and Fisheries in a Tropical Large Indian Reservoir: Insights From a Long‐Term Data Series For Sustainable Development
Authors: Parida Pranaya Kumar , Lianthuamluaia Lianthuamluaia , Kayal Tania , Das Basanta Kumar , Sarkar Uttam Kumar , Koushlesh Satish , Behera Bijay Kumar 
Published: October 2021

Abstract
The geographic information systems (GIS) play an important role in all geospatial aspects of assessment, monitoring and management of inland open water resources for strategic development in fisheries sector. In India, reservoir fisheries development is one of the flagship programme and several initiatives have been taken up towards enhancement and sustainable development. The present study investigates spatio-temporal changes in ecology and fisheries in Hirakud reservoir, Odisha build across river Mahanadi which features one of the largest dam in South Asia. The reservoir is mainly utilized for electricity generation, irrigation and offers tremendous scope to support fisheries and livelihood. As per the seasonal variation analysis, water spread area was at the minimum during premonsoon period. Most of the water quality parameters including nitrate, phosphate, BOD and alkalinity were higher in the premonsoon period and overall the parameters were under favourable range for fisheries. The present investigation from the fish landing sites of the reservoir, recorded merely 40 fish species, indicating loss of fish diversity as compared to the historical reports. The IUCN conservation status showed that among the 40 species only one species, Wallago attu is under VU category and 4 species Chitala chitala, Ompok bimaculatus, Ailia colia and Bagarius bagarius are under NT category. The analysis of time series annual fish catch data using ARIMA model forecasted the increasing trend of fish production. The water quality parameters were presented in GIS platform for better understanding of the spatial variations over time. Habitat protection of fish breeding grounds, closed seasons, mesh size regulations, scientific management and community participation are recommended as the measures for conservation of fish diversity and sustainable enhancement of fish production in the reservoir.