bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tensions as a framework for managing work in collaborative workplaces: A review of the empirical studies
Authors: Manca Claudia 
Published: October 2021

AbstractCompanies are increasingly implementing collaborative workplaces (CWs) to promote office collaboration and flexibility. Despite the rapid diffusion of CWs across industries and organizations, research findings suggest that their benefits often fail to materialize due to the existence of tensions and contradictions that develop through the daily actions and interactions of workplace users. This literature review sheds some light on the development of tensions and contradictions in CWs by focusing on their implications for social relations at work. This review identifies the oppositional tensions that surface in CW research findings:flexibility vs structure,fluidity vs stabilityandexposure vs privacy. In disclosing the underlying mechanisms, this study connects these tensions and their management to the autonomy–control paradox that emerges in CWs. It concludes by suggesting some approaches that are available to managers to assist them in dealing with tensions and unleashing creativity, participation and adaptability.
Transnational education for regional economic development? Understanding Malaysia's and Singapore's strategic coupling in global higher education
Authors: Schulze Marc Philipp , Kleibert Jana Maria 
Published: October 2021

AbstractFostering innovation and upskilling labour pools have become key goals in national economic development plans and education and training system reforms since the mid‐1990s. For their transformation into knowledge‐based economies, countries in Southeast Asia have relied on importing transnational higher education providers and have envisioned themselves as international education hubs. As existing research from transnational education and higher education governance studies as well as economic geography and regional studies has not sufficiently addressed this nexus of transnational education and regional economic development, this paper investigates the role of foreign higher education institutions in economic development strategies in Malaysia and Singapore. It explores why and how states have strategically coupled their higher education systems with transnational education. The comparative case analysis draws on empirical evidence from 42 semi‐structured interviews. It finds that despite the two states' ostensibly similar ambitions to attract foreign higher education institutions, policies and outcomes differ strongly. Whereas in Malaysia a structural coupling led foreign subsidiaries to provide foreign degrees to domestic students and generate revenue in the private higher education sector, in Singapore foreign subsidiaries have been deployed strategically to upgrade the talent pool and public higher education system of the city‐state via functional coupling. Conceptualizing transnational education policies as forms of strategic coupling contributes to understanding their embeddedness within states' broader, historically formed economic development strategies.
Post‐traumatic stress symptoms during the first and second COVID‐19 lockdown in Greece: Rates, risk, and protective factors
Authors: E. Kalaitzaki Argyroula , Tsouvelas George , Tamiolaki Alexandra , Konstantakopoulos George 
Published: October 2021

AbstractThe aim was to (i) compare the rates of perceived stress, post‐traumatic stress symptoms (PTSS) and other potential correlates (i.e., resilience, social support, coping strategies, and loneliness) in the general population between the two COVID‐19 lockdowns in Greece and (ii) explore risk and protective factors of PTSS. Online data were collected amid the first (timepoint 1‐T1) and second lockdown (timepoint 2‐T2) by 1009 and 352 participants, respectively. The PTSD Checklist for DSM‐5 and the Perceived Stress Scale measured levels of PTSS and perceived stress. The Brief Resilience Scale, the COPE, the revised UCLA Loneliness Scale, and the ENRICHD Social Support Instrument measured resilience, coping strategies, loneliness, and social support, respectively. Higher levels of PTSS and perceived stress were reported during T2, compared to T1. Clinically significant levels of PTSS were presented by 26.1% and 35.5% of the participants during T1 and T2, respectively. Higher levels of loneliness and use of maladaptive coping strategies and lower levels of social support, resilience and use of adaptive coping strategies were also found. During both lockdowns, PTSS were predicted by perceived stress, loneliness, reduced resilience and the coping strategies of denial and self‐blame. PTSS were associated with younger age, female gender, being single, not having children, and the evaluation of the pandemic as a crisis. The findings highlight the significant public mental health concerns during the COVID‐19 lockdowns. Understanding the risk and protective factors against PTSS and focusing on vulnerable populations should be prioritized by the governments worldwide in the development of evidence‐based interventions.
Salinity tolerance of lentil is achieved by enhanced proline accumulation, lower level of sodium uptake and modulation of photosynthetic traits
Authors: Panuccio Maria R. , Romeo Federico , Marra Federica , Mallamaci Carmelo , Hussain Muhammad Iftikhar , Muscolo Adele 
Published: October 2021

AbstractLentil (Lens culinaris, Medik.), an accessible low‐cost high‐quality protein form for many people, is a salt‐sensitive legume, which already at an electrical conductivity (EC) of 3 dS/m (~30 mM NaCl) has a yield loss of about 90% compared to other crops. Identifying salinity‐tolerant lentil germplasm is nowadays of primary importance for ensuring the production of superfood and the sustainability of the lentil industry. In this study, four cultivars Castelluccio di Norcia, Eston, Ustica and Pantelleria were grown up to a complete life cycle, in an open field, in soils conditioned with 100 mM NaCl and were compared with the same cultivars grown in unsalinized soils. Growth parameters, osmolytes and phenotypic characteristics of lentils were assessed. Our results evidenced different mechanisms specific for each tolerant cultivar. Pantelleria was the cultivar that mostly accumulated sodium in shoot and root and used it in addition to proline as osmoregulatory. Ustica accumulated less sodium and calcium than Pantelleria but more chlorine in root and enhanced also the production of the osmoregulatory. Castelluccio accumulated less sodium but more calcium and sulphates than the other two resistant cultivars, producing at the same time also osmolytes. The preference of ion uptake and compartmentalization can depend on the growth environment. PANT and UST are islander, therefore, prevalently in contact with sodium and chlorine, while CAST originated from central Italy is cultivated in soil where calcium and sulphate are the most abundant element.
Informal caregivers of people with heart failure and resilience: A convergent mixed methods study
Authors: Durante Angela , Ahtisham Younas , Cuoco Angela , Boyne Josiane , Brawner Bridgette , Juarez‐Vela Raul , Vellone Ercole 
Published: October 2021

AbstractAimTo develop a comprehensive understanding of resilience and its associated factors among informal caregivers of people with heart failure.DesignTransnational multicentre convergent mixed methods approach.MethodsThis study was conducted in three European countries: Italy, Spain and the Netherlands; during February 2017 and December 2018. In total, 195 caregivers completed the Connor–Davidson Resilience Scale, Caregiver Burden Inventory and Hospital Anxiety and Depression Scale. From a nested sample 50 caregivers participated in semi‐structured face‐to‐face interviews. Data were analysed using qualitative content analysis, multiple regression and joint displays.ResultsThe caregivers’ mean age was over 60 years. The quantitative results showed that caregivers experienced anxiety and depression regardless of a good score of resilience and moderate level of burden. Regression analysis showed that the resilience was associated with caregiver depression. From qualitative findings three resilience inhibiting (psychological outlook, physical weariness and affective state) and two promoting factors (community interconnectedness and self‐comforting activities) were generated. Mixed analysis confirmed that depression decreased caregivers’ resilience.ConclusionsCaregivers of people with heart failure experience continuous stress and anxiety resulting in reduced resilience. Collaborative efforts are needed to build multifaceted interventions and programs to enhance caregivers’ resilience by targeting the factors identified in this study.ImpactThe quality of informal caregiving is affected by the resilience of caregivers. No research has explored the resilience levels and its factors in this population. Depression, psychological outlook, physical weariness and affective state are negative factors of caregivers’ resilience. Personal strategies combined with social and community support and belongingness enhance caregivers’ resilience. Community care organizations and hospitals could establish alliances to develop programs for enhancing caregivers’ resilience.
Through the eyes of the founder: CEO characteristics and firms’ regulatory filings
Authors: Hendricks Bradley E. , Lang Mark , Merkley Kenneth 
Published: October 2021

AbstractWe examine whether textual attributes of founder‐led firms’ regulatory filings reflect founder‐CEO characteristics and whether investors consider this relation when assessing firm value. We build on prior research that shows founders have unique personality attributes, particularly overoptimism. Our results suggest that 10‐K text for founder‐led firms is characterized by “excess” optimism relative to current and future realized earnings and relative to non‐founder‐led firms. The effect is mitigated for firms with large auditors, high litigation risk and high analyst following. Based on the stock price at the 10‐K release, investors do not appear to appropriately discount the tone, resulting in predictable negative returns during the year subsequent to the 10‐K release, particularly for the first 2 years after firms go public. Collectively, our findings contribute to the existing literature examining the effects of executives on firm disclosure by providing initial evidence about the conditions under which firms’ scripted narrative disclosures reflect CEO characteristics.
Reduced host‐plant specialization is associated with the rapid range expansion of a Mediterranean butterfly
Authors: Neu Anika , Lötters Stefan , Nörenberg Linda , Wiemers Martin , Fischer Klaus 
Published: October 2021

AbstractAimSpecies ranges are highly dynamic, shifting in space and time as a result of complex ecological and evolutionary processes. Disentangling the relative contribution of both processes is challenging but of primary importance for forecasting species distributions under climate change. Here, we use the spectacular range expansion (ca. 1000 km poleward shift within 10 years) of the butterfly Pieris mannii to unravel the factors underlying range dynamics, specifically the role of (i) niche evolution (changes in host‐plant preference and acceptance) and (ii) ecological processes (climate change).LocationProvence‐Alpes‐Côte d’Azur, France; North Rhine‐Westphalia, Rhineland‐Palatinate and Hesse, Germany.TaxonInsect and angiosperms.MethodsWe employed a combination of (i) common garden experiments, based on replicated populations from the species’ historical and newly established range and host‐plant species representative for each distribution range, co‐occurrence analyses and (ii) grid‐based correlative species distribution modelling (SDM) using Maxent.ResultsWe observed changes in oviposition preference, with females from the newly established populations showing reduced host‐plant specialization and also an overall increased fecundity. These changes in behaviour and life history may have enabled using a broader range of habitats and thus facilitated the recent range expansion. In contrast, our results indicate that the range expansion is unlikely to be directly caused by anthropogenic climate change, as the range was not constrained by climate in the first place.Main conclusionsWe conclude that evolution of a broader dietary niche rather than climate change is associated with the rapid range expansion, and discuss potential indirect consequences of climate change as trigger for the genetic differences found. Our study thus illustrates the importance of species interactions in shaping species distributions and range shifts, and draws attention to indirect effects of climate change. Embracing this complexity is likely the key to a better understanding of range dynamics.
Procedural and short‐term results of electroanatomic‐mapping‐guided ganglionated plexus ablation by first‐time operators: A multicenter study
Authors: Aksu Tolga , De Potter Tom , John Leah , Osorio Jose , Singh David , Alyesh Daniel , Baysal Erkan , Kumar Kapil , Mikaeili Javad , dal Forno Alexander , Yalin Kivanc , Akdemir Baris , Woods Christopher E. , Salcedo Jonathan , Eftekharzadeh Mahmoud , Akgun Taylan , Sundaram Sri , Aras Dursun , Tzou Wendy S. , Gopinathannair Rakesh , Winterfield Jeffrey , Gupta Dhiraj , Davila Andre 
Published: October 2021

AbstractIntroductionSingle‐center observational studies have shown promising results with fragmented electrogram (FE)‐guided ganglionated plexus (GP) ablation in patients with vagally mediated bradyarrhythmia (VMB). We aimed to compare the acute procedural characteristics during FE‐guided GP ablation in patients with VMB performed by first‐time operators and those of a single high‐volume operator.Methods and ResultsThis international multicenter cohort study included data collected over 2 years from 16 cardiac hospitals. The primary operators were classified according to their prior GP ablation experience: a single high‐volume operator who had performed > 50 GP ablation procedures (Group 1), and operators performing their first GP ablation cases (Group 2). Acute procedural characteristics and syncope recurrence were compared between groups. Forty‐seven consecutive patients with VMB who underwent FE‐guided GP ablation were enrolled, n = 31 in Group 1 and n = 16 in Group 2. The mean number of ablation points in each GP was comparable between groups. The ratio of positive vagal response during ablation on the left superior GP was higher in Group 1 (90.3% vs. 62.5%, p = .022). Ablation of the right superior GP increased heart rate acutely without any vagal response in 45 (95.7%) cases. The procedure time was longer in group 2 (83.4 ± 21 vs. 118.0 ± 21 min, respectively, p < .001). Over a mean follow‐up duration of 8.0 ± 3 months (range 2–24 months), none of the patients suffered from syncope.ConclusionThis multi‐center pilot study shows for the first time the feasibility of FE‐guided GP ablation across a large group of procedure‐naïve operators.
CircGFRA1 facilitates the malignant progression of HER‐2‐positive breast cancer via acting as a sponge of miR‐1228 and enhancing AIFM2 expression
Authors: Bazhabayi Meiheban , Qiu Xingsheng , Li Xing , Yang Anli , Wen Wei , Zhang Xiaoli , Xiao Xiangsheng , He Rongfang , Liu Peng 
Published: October 2021

AbstractCircRNAs (circular RNA) are reported to regulate onset and progress multiple cancers. Nonetheless, the function along with the underlying mechanisms of circRNAs in HER‐2‐positive breast cancer (BC) remains unclear. CircRNA microarrays were performed to elucidate expression profiles of HER‐2‐positive BC cells. circRNA levels were quantified using qRT‐PCR assay. Various in vitro along with in vivo assays were employed to further explore the effects of circGFRA1 in the progress of HER‐2‐positive BC and interactions of circGFRA1, miR‐1228 and AIFM2 in Her‐2‐positive BC. CircGFRA1 was remarkably upregulated in HER‐2‐positive BC. Knockdown of circGFRA1 could attenuate HER‐2‐positive BC progression by inhibiting the proliferation, infiltration and migratory ability of HER‐2‐positive BC cells. Through ceRNA mechanism, circGFRA1 could bind to miR‐1228 and alleviate inhibitory activity of miR‐1228 on targeted gene AIFM2. In summary, circGFRA1‐miR‐1228‐AIFM2 axis regulates HER‐2‐positive BC. CircGFRA1 is a novel promising treatment option for HER‐2‐positive BC.
2‐Deoxy‐D‐glucose impedes T cell–induced apoptosis of keratinocytes in oral lichen planus
Authors: Wang Fang , Zhang Jing , Zhou Gang 
Published: October 2021

AbstractOral lichen planus (OLP) is a T cell–mediated immunoinflammatory disease. Glycolysis plays an essential role in T‐cell immune responses. Blocking glycolytic pathway in activated T cells represents a therapeutic strategy for restraint of immunologic process in autoimmune disorders. 2‐Deoxy‐D‐glucose (2‐DG) has been widely used to probe into glycolysis in immune cells. This study was aimed to explore the role of glycolysis inhibition by 2‐DG on regulating immune responses of OLP‐derived T cells. We observed that lactic dehydrogenase A (LDHA) expression was elevated in OLP lesions and local T cells. 2‐DG inhibited the expression of LDHA, p‐mTOR, Hif1α and PLD2 in T cells; meanwhile, it decreased proliferation and increased apoptosis of T cells. T cells treated by 2‐DG showed lower LDHA expression and elevated apoptosis, resulting in a reduced apoptotic population of keratinocytes that were co‐cultured with them, which was related to the decreased levels of IFN‐γ in co‐culture system. Rapamycin enhanced the effects of 2‐DG on immune responses between T cells and keratinocytes. Thus, these findings indicated that OLP‐derived T cells might be highly dependent upon high glycolysis for proliferation, and 2‐DG treatment combined with rapamycin might be an option to alleviate T‐cell responses, contributing to reducing apoptosis of keratinocytes.
Glycerol‐plasticized chitosan film for the preservation of orange
Authors: Nguyen Thuong Thi , Phan Ngoc‐Huyen Thi , Trinh Chinh Dung , Tran Thuan Van , Pham Bao‐Tran Tran , Quynh Bui Thi Phuong , Phung Thanh Khoa 
Published: October 2021

AbstractGreen thin films for food packaging are essential and growing in recent years to reduce the dependence on petroleum‐derived plastics. In this study, the glycerol‐plasticized chitosan film incorporated with 1–3% of crude Piper betel Linn. leaf (PBLL) extract was prepared via facile casting process and was characterized by scanning electron microscope, attenuated total reflection‐Fourier transform infrared, thermogravimetric analysis, X‐ray diffraction, UV–Vis, contact angle, water content, antimicrobial, and antioxidant activities. The film improved the protective properties of the sole chitosan and enhanced the UV‐blocking ability of glycerol‐plasticized chitosan film in the regions of Ultraviolet B (280–320 nm) and Ultraviolet A (320–390 nm), resulting in suitable film for food packaging applications. Furthermore, the presence of PBLL extract predominantly containing phenolic compounds in blend film induced very strong antimicrobial activities against Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhimurium, and Escherichia coli. The modified chitosan films increased the hydrophilic property resulting in high potential in degradability and can also protect the king orange by coating with the shelf life‐prolonging up to 18 days at 20°C with acceptable appearance and texture. Our results can be developed to produce industrial green thin films to protect fruits during transportation and preservation.
Diagnostic yield of microarrays in individuals with non‐syndromic developmental delay and intellectual disability
Authors: Oğuz S. , Arslan U. E. , Kiper P. Ö. Ş. , Alikaşifoğlu M. , Boduroğlu K. , Utine G. E. 
Published: October 2021

AbstractBackgroundIntellectual disability (ID), or developmental delay (DD) when the individual is yet under 5 years of age, is evident before 18 years of age and is characterised by significant limitations in both intellectual functioning and adaptive behaviour. ID/DD may be clinically classified as syndromic or non‐syndromic. Genomic copy number variations (CNVs) constitute a well‐established aetiological subgroup of ID/DD. Overall diagnostic yield of microarrays is estimated at 10–25% for ID/DD, especially higher when particular clinical features that render the condition syndromic accompany.MethodsIn this study, we aimed to investigate the diagnostic yield of microarrays in the subgroup of individuals with non‐syndromic ID/DD (NSID/NSDD). A total of 302 NSID/NSDD individuals who have undergone microarray analysis between October 2013 and April 2020 were included. Accompanying clinical data, including head circumference, delayed developmental areas, seizures and behavioural problems were collected and analysed separately in NSID and NSDD subgroups.ResultsThe diagnostic yield of microarray analyses in NSID/NSDD was determined as 10.9% in NSID (10.7%) and in NSDD (11.1%). Presence of behavioural and epileptic problems did not contribute to the diagnostic yield. However, in the presence of macrocephaly, the contribution to diagnostic yield was statistically significant particularly in NSDD group. The most common pathogenic CNVs involved chromosomes 16, 15 and X. Lastly, we propose a Xq21.32q22.1 deletion as likely pathogenic in a child with isolated language delay and accompanying seizures.ConclusionsParticularly in neurodevelopmental diseases, microarrays are useful for establishing the diagnosis and detecting novel susceptibility regions. Future studies would accurately classify the herein presented variants of uncertain significance CNVs as pathogenic or benign.
Trends and hot topics in nurse empowerment research: A bibliometric analysis
Authors: Yesilbas Hande , Kantek Filiz 
Published: October 2021

AbstractAimThe characteristics of the publications on nursing empowerment should be investigated in order to get an idea about the development of the field and to determine the developments in nursing practices and research. This study aimed to investigate the characteristics of the current knowledge structure and developmental process in nurse empowerment by using bibliometric methods.MethodsThe data of this retrospective descriptive study were obtained from the Web of Science (WoS). All relevant studies conducted before 2020 were included in the study. The data analysis was conducted with Excel, SPSS and VOSviewer.ResultsFive hundred eighty‐nine studies conducted between 1974–2019 were included in the study. It was found that 72.15% of these studies were journal articles and these studies were conducted by 1,450 authors. The studies were published in 109 journals and were produced by researchers from 49 different countries. Also 47.5% of these studies were conducted in the United States. Hot topics were “empowerment”, “nursing,” “structural empowerment,” “nurses,” “job satisfaction” and “psychological empowerment.”ConclusionThere has been a noteworthy increase in the number of studies on nurse empowerment and this field offers an active field of study for nursing researchers. The focus of the studies varies from nurses to nurse managers.