bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effectiveness of the Finger Grip Relaxation Technique to Reduce Pain Intensity in Post-Appendectomy Patients: A Literature Review
Authors: Calisanie Nyayu Nina Putri , Ratnasari Anisa Nur 
Published: March 2021

Appendicitis is an inflammation of the appendix. Post-appendectomy patients often experience pain from the surgical wound incisions. Pain will have an impact on daily activities. Therefore, independent nursing action is needed by performing simple and easy pain management; one methods is finger grip relaxation. To measure the effect of finger relaxation techniques on pain reduction in post-appendectomy patients, this study used a literature review method. The data was collected by searching on Google Scholar website with the following keywords: Finger Grip Relaxation Techniques, Pain, and Appendicitis. It was found that in post-appendectomy surgery patients before being given a finger grip relaxation technique, the patients experienced moderate pain, then after being given a finger grip relaxation technique, the pain intensity decreased and effectively. Data were analysed by Paired T-Test with a significant value α=0.005. The results showed the average result before intervention was 4.80 and the average result after intervention was 3.87. The bivariate results obtained p-value 0,000. It shows that there are differences in pain intensity before and after finger grip relaxation techniques are performed in post-appendectomy patients [3]. It can be concluded that finger grip relaxation techniques can be used as an intervention in the hospital or at home to reduce pain in post-appendectomy patients.

Keywords: Finger Grip Relaxation Techniques, Pain, Appendicitis.
Exploring Physical Problems among Postpartum Women with Hiv/AIDS in West Java, Indonesia: A Qualitative Study
Authors: Nurhayati Nunung , Hendra Agus 
Published: March 2021

Indonesia is experiencing the fastest HIV/AIDS cases development in Asia, especially with regards to mother to child transmission levels. Postpartum women with HIV may suffer from a lot of physical problems due to the immune system disruption. Many of them have high risk for opportunistic infection such as tuberculosis, chronic diarrhea, and meningitis. Few studies have been conducted into these physical problems, especially in a low income country whereas the access to HIV drugs is still limited. This study aims to explore the physical problems among postpartum women with HIV/AIDS in West Java, Indonesia. This study used a qualitative design with a phenomenology approach. The semi-structured interview was used to collect information from women of between 24 and 38 years old, with a child with a maximum age of 12 months, and various other inclusion criteria. Purposive sampling was applied to select the participants. Colaizzi’s method was used to analyze the data. Six participants agreed to join in this study. We found three themes concerning the major physical problems experienced by postpartum women with HIV/AIDS: 1) physical response toward disease prognosis; 2) body weight changes, and 3) the side effects of HIV drugs. The most common physical symptoms were exhaustion, fever, headache, low back and joint pain, nausea, and weight change. Physical symptoms management design and implemented in health care services should provided for HIV/AIDS patients.

Keywords: HIV/AIDS, Physical, Problems, Postpartum women, qualitative study
Risk Factors Of Preeclampsia Among Pregnant Women In Indonesia
Authors: Fitriani Hemi , Setya R Achmad , Keni Marcelina 
Published: March 2021

Preeclampsia is the second highest cause of maternal death in Indonesia. The incidence of preeclampsia in Indonesia is very high at 24%. West Java is a province in Indonesia with a high preeclampsia rate of 25%. Predisposing factors include preeclampsia including age. Health Research Data (2010) shows that the percentage of early marriage aged <20 years is still high at 46.7% and marriage age> 35 years at 0.6%. Objectives This study aims to determine the relationship between age and the incidence of preeclampsia at Dustira Hospital in Cimahi City. This study was conducted using the correlation with the case control approach. The population in this study was 130 postpartum mothers treated at Dustira Level II Hospital. The sampling technique used purposive sampling with a total of 24 for the preeclampsia group and 24 for the non-preeclampsia group. The data collected is secondary data collected by observing the medical record book. The research instrument uses a checklist sheet. The study was conducted in June 2019 at Dustira City II Kindergarten Hospital Cimahi. Univariate analysis uses frequency distribution and bivariate uses chi-square. Univariate test results showed that the incidence of preeclampsia was mostly experienced by pregnant women with age at risk of 58.3%. Bivariate test results showed a p value of 0.007 (α <0.05) and OR 7 (95% CI: 1.822-26.887) meaning that there was a relationship between age and the incidence of preeclampsia, and mothers with age at risk had 7 times greater occurrence of preeclampsia compared to age is not at risk. Pregnant women aged less than 20 years or more than 35 years are at high risk of experiencing preeclampsia. One of the efforts to prevent the occurrence of preeclampsia is through health promotion about the age of mothers who are safe to reproduce. It is expected that health workers, especially maternity nurses, can provide health services to the public regarding the ideal age for pregnancy or childbirth as well as the age at risk of preeclampsia.

Keywords: Indonesia, Maternal age pregnancies, Preeclampsia
The Anti-tubercular Activity of Noni Fruitsto Inhibition Growth of Multi Drug Resistant-Tuberculosis Bacteria
Authors: Mauliku Novie Elvinawaty 
Published: March 2021

Multidrug-resistant tuberculosis (MDR-TB) is a tuberculosis infection that is resistant to the treatment at least two of the most powerful anti-tuberculosis drugs, such as Isoniazid and Rifampisin. Increased cases of MDR-TB in morbidity and mortality become obstacles in the control of tuberculosis (TB), thus requiring supportive treatment of natural ingredients that can contribute in the treatment of TB, such a noni fruit. The main objective of this study was extract of noni fruits to inhibition the growth of strain MDR-TB bacteria, and compered it with the anti-TB drugs. The Morinda c. Linn (Noni) fruits was extraced by ethanol (96%). The extract was filtered through whatman No.1 filter paper, evaporated to dryness on a water bath until the solvent evaporated completely and yield of the crude extract. The experiment were divided into 3 groups, i.e.: negative control: group I; positive control: group II; crude extracts noni fruit: group III: combinations of crude extracts noni fruit and anti-TB drugs (K, AK, and OF). Each group was divided into three groups’ doses of 30 mg/ml, 40 mg/ml and 50 mg/ml. The Anti-tuberculosis activities of extracts noni fruit and K, AK, and OF against TB-MDR bacteria were tested by susceptibility test using proportion method in Lowenstein-Jensen (LJ) media.The anti-tubercular activity of noni fruits was determined by the minimum inhibitory concentration (MIC) of the bacterial growth at various doses 30 mg/ml, 40 mg/ml, and 50 mg/ml. The research design used post-test only contol group, and analyzed using analysis of variance and post hoct test. The extracted of Morinda c.Linn (noni) fruits have antitubercular activity to inhibiton of growth MDR-TB bacteria at various doses (p value=0,000). At a dose 30 mg/mlthe mean rate of the growth colonies of MDR TB-bacteria whit the mean rate 59,00 ± 27,81, and at a dose 40 mg/ml was1,50 ± 2,81. While at a dose of 50 mg/ml the bacterial colonies of MDR-TB did not grow in media. The combination of Morinda c.Linn (noni) fruit with anti-tuberculosis drugs, was the smallest groups to inhibit and eliminate MDR-TB bacteria at a dose 30 mg/ml(0,00 ± 00.00). The experimental results confirmed the extracted of Morinda c.Linn (noni) fruits have antitubercular activity as well as anti-TB drugs, and the combination of the extracted of Morinda c.Linn (noni) fruits and anti-TB drugs was the best groups to inhibiton of growth MDR-TB bacteria.

Keywords: TB-MDR Bacteria, Morinda c. Linn (Noni), Anti-TB drugs, Anti-tubercular activity, MIC.
ELISA versus Nested PCR for Detection of Hepatitis B Co-infection in HIV-infected People in Bandung Indonesia
Authors: Naully Patricia Gita 
Published: March 2021

The number of Human Immunodeficiency Virus infected patients in Bandung is increasing. HIV patients are often suffering from Hepatitis B Virusco-infection. The co-infection status must be detected using the accurate method. This study aims to compare the accuracy of Enzyme-Linked Immunosorbent Assay and nested Polymerase Chain Reaction in detecting HIV-HBV co-infection in Bandung. The research method used is experimental. The sample used in this study was 50 people. All samples had met the inclusion criteria. The presence of hepatitis B surface antigen in the serum was detected using a qualitative ELISA Wantai kit, while sHBsAg gene in the whole blood was amplified using 2 pairs of the specific primary. The results obtained from both methods were analyzed to determine sensitivity, specificity, and accuracy values. The result of Hepatitis B detection using ELISA method showed that 15 samples (30%) were positive, 1 sample (2%) was a false positive, and 3 samples (6%) were the false negative. Moreover, the nested PCR method showed that 18 samples (36%) were positive without false positive or false negative result. These results showed that ELISA has a sensitivity value of 83.33%, specificity of 96.87%, and the accuracy of 92%, while Nested PCR has a value of 100% for all three parameters. Therefore, it can be concluded that the Nested PCR method was more accurate than ELISA to detect Hepatitis B co-infection in HIV patients in Bandung.The Nested PCR can be recommended for detecting the other co-infection cases.

Keywords: accuracy, HBsAg, co-infection, sensitivity, specificity
Liver Histopathological Measurement Due to Maximum Dosage for Acute Oral Toxicity Test Using Ethanol Extract Of Coffee Pulp In Female Mice
Authors: Khristian Erick 
Published: March 2021

Coffee processing into fast food ingredients that must be done in order to get maximum results. Behind the processing there are various problems that arise, one of them are the presence of solid waste in the form of pulp coffee. Based on several studies, coffee pulp turned out to have high antioxidants.This research was conducted an acute oral toxicity test of the maximum dose (2000 mg/kg BW) of ethanol extract of coffee pulp was tested on mice for 24 hours. Acute oral toxicity studies of coffee pulp based on guidelines for National Drug and Food Control in female mice. The study was conducted in 2 groups of test animals consisting of a negative control group and an acute oral treatment group. Each group of 5 mice were treated for 24 hours. After treatment, the object was analyzed by histological observations descriptively. Descriptive histological analysis (qualitative analysis) of the liver of female mice showed no difference between the study groups. The treatment group that was given ethanol extract of coffee pulp showed a normal nucleus which was shown by the appearance of scattered chromatin beads. This is in line with the description of the normal cytoplasm like a group of normal mice. The maximum dose of 2,000 mg / kg for acute oral testing for 24 hours does not show microscopic changes in female mice.Recommendation for further research is to conduct oral subchronic and chronic toxicity testing in the normal group and in groups given free radical-producing compounds with various examinations of other organs.

Keywords: health drinks, antioxidant, acute toxicity, maximum dose.
Pola Komunikasi Antar Pribadi Orang Tua dan Anak dalam Meningkatkan Kemandirian Anak Usia 4-6 Tahun
Authors: Jaelany Andhi Ardhian , Purba Veny 
Published: March 2021

Penelitian ini dilakukan untuk menjelaskan pola komunikasi antarpribadi orangtua dan anak dalam meningkatkan kemandirian anak di TK Waladun Sholeh. Penelitian ini menggunakan metode kualitatif dengan subjek penelitiannya adalah orangtua dan guru di TK Waladun Sholeh. Objek penelitian adalah proses interaksi orangtua dalam mengembangkan kemandirian anak. Data dikumpulkan melalui wawancara mendalam dan dokumen analisis. Hasil penelitian bahwa proses komunikasi yg terjalin antara orangtua & anak efektif. Hal ini ditimbulkan karena adanya hubungan yg terjalin antara orangtua dan anak secara terus menerus dalam kegiatan sehari-hari.
Personalized Medicine and Chronic Kidney Disease in Sub-Saharan Africa: Advances and Challenges
Authors: Winkler Cheryl A. 
Published: March 2021

Abstract
Chronic kidney disease is increasing in prevalence sub-Saharan Africa, largely driven by the growing burden of hypertension, obesity, diabetes, and HIV infection. Underlying common and rare genetic variants may add to this risk at both the individual and population levels.
Here we explore the advances and challenges in the translation of genetic discovery to personalized medicine for chronic kidney disease (CKD) in children and adults living in sub-Saharan Africa. The review discusses monogenic and polygenic causes of CKD with a focus on the African-specific APOL1 and NPHS2 variants. In summary, advances in genomics research capacity herald improvement in health outcomes through personalized medicine, precision molecular diagnosis of diseases, and through public health initiatives targeting high-risk populations.
Higiene sanitasi makanan dan analisis nomor P-IRT pada kerupuk berwarna merah (Studi pasar Kepanjen Kabupaten Malang)
Authors: Kurniasari Dieka Armanda , Pujiati Rahayu Sri , Ningrum Prehatin Trirahayu 
Published: March 2021

Food sanitation hygiene has been done to control food factor, people, place and tools in order to prevent cross contamination between food and eater. Household food industry must possess household food industry certificate or SPP-IRT to aid supervision by involved parties. The aim of this research was to discover food sanitation hygiene and analysis P-IRT number on red-coloring crackers at Kepanjen Market in Malang. Thisresearch is descriptive research with observation and interview methods to cracker industry workers and there were 12 kinds of red-coloring crackers distributed around Kepanjen Market. The research used univariant analysis to describe variable of those which were observed. This research it was found that there were three stages in cracker making process, Food sanitation hygiene, and P-IRT number on red-coloring crackers. From this research there were 3 of respondents around < 40 years old, all respondents in secondary education, and 2respondents had < 3 years of working period. The application of food hygiene and sanitation of cracker industry in Malang Regency was categorized as relatively good. There were 7 red-coloring crackers traded at Kepanjen Market were qualified as what had been standardized by BPOM number 22 year 2020. Meanwhile, there were 4 products were not updated and 1 product was not qualified.
Bittersweet
Authors: Schnall Adrian M. 
Published: March 2021

The winner has been declared.A flood of relief!Exultation! Dancing in the streets!And a gasp of horror.How can there be tens of millions on the other side? So many morethan a couple dozen Proud Boys,a few towns of hillbilly farmers, a frenzied rally crowd chanting Lock her up.It’s fathers and mothers, sisters and brothers,face upon human face.Is it them or us? Who are the blind? Fires still flare on the battlefield – one is raging on and off in the distance. But every blaze is dying as I watch. Great conflagrations are turning to ash.The forecast is for snowon the mountaintops, in the streets,in the corridors of State.Pride needs to go into hibernation.I think the air will be clearin the morning. I think I will hear music in the trees.But no one is surrenderinghis gun.
KELAYAKAN BAHAN AJAR ELASTISITAS DAN HUKUM HOOKE BERBASIS INKUIRI TERBIMBING UNTUK MELATIHKAN KETERAMPILAN PROSES SAINS PESERTA DIDIK
Authors: Rahmawati Iqrima , Mastuang Mastuang , Suyidno Suyidno , Sunarti Titin 
Published: March 2021

Abstrak: Keterampilan proses dan aktivitas sains termasuk keterampilan dasar dalam belajar fisika, namun kurang dilatihkan di sekolah. Oleh karena itu, penelitian ini bertujuan untuk menghasilkan bahan ajar elastisitas dan hukum Hooke berbasis inkuiri terbimbing yang layak untuk melatihkan keterampilan proses peserta didik. Penelitian pengembangan ini menggunakan desain model ADDIE. Uji coba dilakukan pada 23 peserta didik di kelas XI IPA 1 SMAN 12 Banjarmasin. Data dikumpulkan melalui instrumen validasi bahan ajar, pengamatan keterlaksanaan RPP dan aktivitas sains, serta tes hasil belajar. Teknik analisis dilakukan secara deskriptif kualitatif dan n-gain. Hasil penelitian menunjukkan: (1) setiap komponen RPP, LKPD, materi ajar, dan THB dalam kriteria valid, (2) setiap komponen RPP dapat dilaksanakan dengan baik, (3) aktivitas sains peserta didik dalam kriteria sangat baik, dan (4) keterampilan proses dan hasil belajar peserta didik meningkat dalam kriteria sedang. Dengan demikian, bahan ajar elastisitas dan hukum Hooke berbasis inkuiri terbimbing termasuk layak untuk melatih keterampilan proses sains peserta didik. Kata kunci: Bahan ajar, elastisitas dan hukum Hooke, inkuiri terbimbing, keterampilan proses sains
MENINGKATKAN HASIL BELAJAR DAN KETERAMPILAN INKUIRI PESERTA DIDIK PADA MATERI POKOK TEKANAN ZAT MELALUI PENERAPAN MODEL ARGUMENT DRIVEN INQUIRY (ADI)
Authors: M Hunaidah , Erniwati Erniwati , Sukariasih Luh 
Published: March 2021

Abstrak: Penelitian ini bertujuan untuk mendeskripsikan peningkatan hasil belajar dan keterampilan inkuiripeserta didik kelas VIII3 SMP Negeri 8 Kendari pada materi pokok tekanan zat melalui penerapan model pembelajaran Argument driven Inquiry (ADI). Jenis penelitian ini adalah Penelitian Tindakan Kelas (PTK) yang dilaksanakan dalam 2 (dua) siklus. Hasil penelitian menunjukkan bahwa penerapan model pembelajaran ADI dapat: (1) meningkatkan hasil belajar baik pada siklus I dengan nilai rata-rata 69,75 maupun siklus II dengan nilai rata-rata 86,79; (2) meningkatkan keterampilan inkuiri baik pada siklus I dengan skor rata-rata sebesar 1,67 dengan kategori cukup maupun siklus II dengan rata-rata 2,66 pada kategori baik. Sehingga dapat dikatakan bahwa penerapan model pembelajaran Argument driven Inquiry (ADI) dapat meningkatkan hasil belajar dan keterampilan inkuiri peserta didik. Kata kunci: Hasil Belajar, Keterampilan Inkuiri, Argument Driven Inquiry (ADI)
Relationship between Number and Order of Children with Exclusive Breastfeeding Practices in Surakarta
Authors: Tjung Vivienne , Umma Husnia Auliyatul , Subandono Jarot 
Published: March 2021

<p class="16"><strong><em>Introduction</em></strong><strong><em>:</em></strong><strong><em> </em></strong><em>Exclusive breast milk is breastfeeding for six months to babies, without providing other foods and drinks. Breastfeeding for up to 6 months is recommended by various health organizations, including the Ministry of Health. In Indonesia, exclusive breastfeeding is still low, even though the benefits of breastfeeding are numerous. Various studies that have been conducted have shown </em><em>different</em><em> results regarding the relationship between the number and sequence of children with breastfeeding practices. This stud</em><em>y </em><em>aimed</em><em> </em><em>to determine the relationship between the number of children and the order of the children with the practice of exclusive breastfeeding in Surakarta</em><em></em></p><p class="16"><strong><em>Methods</em></strong><strong><em>:</em></strong><strong><em> </em></strong><em>This study </em><em>was</em><em> an analytic observational study with a cross-sectional study design. The research sample was determined by random sampling of mothers registered at the Penumping Health Center. The research sample consisted of 50 people who have children aged 1-5 years. Assessment of completeness of breastfeeding was measured using a questionnaire. Data were analyzed using bivariate analysis techniques using chi-square and multivariate logistic regression</em><em>.</em><em></em></p><p class="16"><strong><em>Result</em></strong><strong><em>s and discussions: </em></strong><em>From</em><em> 47</em><em> </em><em>subjects studied with the bivariate analysis technique using the chi square between the number of children and the order of children with exclusive breastfeeding practice, the results were less significant, p = 0.724 and p = 0.401</em><em>.</em><em></em></p><p class="16"><strong><em>Conclusion</em></strong><strong><em>: </em></strong><em>There </em><em>was</em><em> no significant relationship between the number of children and the order of children with the practice of exclusive breastfeeding in Surakarta.</em><em></em></p><p class="18"><strong><em>Keywords</em></strong><strong><em>: </em></strong><strong><em>E</em></strong><strong><em>xc</em></strong><strong><em>lusive breastfeeding, number of children, </em></strong><strong><em>order </em></strong><strong><em>of children</em></strong><strong><em>.</em></strong><strong><em></em></strong></p>
Prediction of Oil and Gas Occurrence in the Jurassic Reservoirs of the Zone of Junction of the Yenisei–Khatanga and West Siberian Basins
Authors: Novikov D.A. , Borisov E.V. 
Published: March 2021

Abstract
—Based on a comprehensive analysis of the geologic structure, hydrogeology, and hydrogeochemistry, we predict oil and gas occurrence in the Jurassic reservoirs of the zone of junction of the Yenisei–Khatanga and West Siberian basins. We have established the regularities of formation of sandstones of the Sigovaya, Malyshevka, Vym, Nadoyakha, Sharapovka, and Zima reservoirs and examined their poroperm properties. The studied Lower and Middle Jurassic deposits, beginning from the Malyshevka reservoir, are characterized by abnormally high formation pressures with an anomaly ratio of up to 1.92. The Jurassic reservoirs bear weakly alkaline, moderately brackish to slightly saline groundwater of Cl Na, Cl–HCO3 Na, and HCO3–Cl Na compositions with TDS = 3.0–23.3 g/dm3. The low-mineralization connate waters determine an inverse vertical hydrogeochemical zoning in the sedimentary cover of the study region.
The research data show favorable conditions for the generation and accumulation of hydrocarbon pools. It is shown that the main criteria for oil and gas occurrence are hydrogeochemical (contents of organic compounds, NH4, B, I, Br, naphthenic acids, and benzene; B/Br and HCO3/Cl coefficients), gas (total gas saturation of formation waters, degree of their gas saturation (Kg), and composition of water-dissolved gases), and hydrodynamic (formation pressures and their anomaly ratio (Ka)) indicators. Also, complex anomalies have been revealed in the Jurassic deposits, which trace the gas fields and revealed oil and gas occurrences.
The Jurassic reservoirs are most promising for structure-lithologic traps in the peripheral zones of the basin and on the slopes of large positive structures. The Middle Jurassic deposits in the interior of the Yenisei–Khatanga Basin, poorly studied by deep drilling, might also be of interest as potential hydrocarbon pools.