bluuebunny/crossref_metadata_2025_split huggingface dataset:
Home-Monitoring Application for Children With Medical Complexity: A Feasibility Trial
Authors: Nkoy Flory , Stone Bryan , Hofmann Michelle , Fassl Bernhard , Zhu Angela , Mahtta Namita , Murphy Nancy 
Published: April 2021

OBJECTIVES:Mobile apps are suggested for supporting home monitoring and reducing emergency department (ED) visits and hospitalizations for children with medical complexity (CMC). None have been implemented. We sought to assess the MyChildCMC app (1) feasibility for CMC home monitoring, (2) ability to detect early deteriorations before ED and hospital admissions, and (3) preliminary impact.METHODS:Parents of CMC (aged 1–21 years) admitted to a children’s hospital were randomly assigned to MyChildCMC or usual care. MyChildCMC subjects recorded their child’s vital signs and symptoms daily for 3 months postdischarge and received real-time feedback. Feasibility measures included parent’s enrollment, retention, and engagement. The preliminary impact was determined by using quality of life, parent satisfaction with care, and subsequent ED and hospital admissions and hospital days.RESULTS:A total of 62 parents and CMC were invited to participate: 50 enrolled (80.6% enrollment rate) and were randomly assigned to MyChildCMC (n = 24) or usual care (n = 26). Retention at 1 and 3 months was 80% and 74%, and engagement was 68.3% and 62.6%. Run-chart shifts in vital signs were common findings preceding admissions. The satisfaction score was 26.9 in the MyChildCMC group and 24.1 in the control group (P = .035). No quality of life or subsequent admission differences occurred between groups. The 3-month hospital days (pre-post enrollment) decreased from 9.25 to 4.54 days (rate ratio = 0.49; 95% confidence interval = 0.39–0.62; P &lt; .001) in the MyChildCMC group and increased from 1.08 to 2.46 days (rate ratio = 2.29; 95% confidence interval = 1.47–3.56; P &lt; .001) in the control group.CONCLUSIONS:MyChildCMC was feasible and appears effective, with the potential to detect early deteriorations in health for timely interventions that might avoid ED and hospitalizations. A larger and definitive study of MyChildCMC’s impact and sustainability is needed.
Nurse/Resident Reciprocal Shadowing to Improve Interprofessional Communication
Authors: Monroe Kimberly K. , Kelley Jennifer L. , Unaka Ndidi , Burrows Heather L. , Marshall Trisha , Lichner Kelli , McCaffery Harlan , Demeritt Brenda , Chandler Debra , Herrmann Lisa E. 
Published: April 2021

OBJECTIVES:
Poor communication is a major contributor to sentinel events in hospitals. Suboptimal communication between physicians and nurses may be due to poor understanding of team members’ roles. We sought to evaluate the impact of a shadowing experience on nurse–resident interprofessional collaboration, bidirectional communication, and role perceptions.

METHODS:
This mixed-methods study took place at 2 large academic children’s hospitals with pediatric residency programs during the 2018–2019 academic year. First-year residents and nurses participated in a reciprocal, structured 4-hour shadowing experience. Participants were surveyed before, immediately after, and 6 months after their shadowing experience by using an anonymous web-based platform containing the 20-item Interprofessional Collaborative Competency Attainment Survey, as well as open-ended qualitative questions. Quantitative data were analyzed via linear mixed models. Qualitative data were thematically analyzed.

RESULTS:
Participants included 33 nurses and 53 residents from the 2 study sites. The immediate postshadowing survey results revealed statistically significant improvements in 12 Interprofessional Collaborative Competency Attainment Survey question responses for nurses and 19 for residents (P ≤ .01). Subsequently, 6 questions for nurses and 17 for residents revealed sustained improvements 6 months after the intervention. Qualitative analysis identified 5 major themes related to optimal nurse–resident engagement: effective communication, collaboration, role understanding, team process, and patient-centered.

CONCLUSIONS:
The reciprocal shadowing experience was associated with an increase in participant understanding of contributions from all interprofessional team members. This improved awareness may improve patient care. Future work may be conducted to assess the impact of spread to different clinical areas and elucidate patient outcomes that may be associated with this intervention.
Manos que mecen la cuna
Authors: Osta Vázquez María Laura 
Published: April 2021

Este artigo propor-se pesquisar a relacao que existiu entre a difusao do discurso maternalista, promovido pelos médicos, políticos, sacerdotes, filósofos, e o declive da professao de nodriza em Montevideo do seculo XIX. A partir dum análise de género se buscará identificar os vínculos de poder representados no tratamento e disciplinamento dos corpos dessas mulheres em grande parte pretas, mestizas e extrangeiras. Para isso se analizará emprensa, registros da policia, cartas, informes médicos e catálogos de livrarías, procurando rastros do discurso maternalista (proveniente do higienismo médico) que intentavam criticar e desvalorizar a labor das nodrizas que muito útiles e de moda tinham estado durante o seculo XVIII e parte do XIX.
MADRaS : Multi Agent Driving Simulator
Authors: Santara Anirban , Rudra Sohan , Buridi Sree Aditya , Kaushik Meha , Naik Abhishek , Kaul Bharat , Ravindran Balaraman 
Published: April 2021

Autonomous driving has emerged as one of the most active areas of research as it has the promise of making transportation safer and more efficient than ever before. Most real-world autonomous driving pipelines perform perception, motion planning and action in a loop. In this work we present MADRaS, an open-source multi-agent driving simulator for use in the design and evaluation of motion planning algorithms for autonomous driving. Given a start and a goal state, the task of motion planning is to solve for a sequence of position, orientation and speed values in order to navigate between the states while adhering to safety constraints. These constraints often involve the behaviors of other agents in the environment. MADRaS provides a platform for constructing a wide variety of highway and track driving scenarios where multiple driving agents can be trained for motion planning tasks using reinforcement learning and other machine learning algorithms. MADRaS is built on TORCS, an open-source car-racing simulator. TORCS offers a variety of cars with different dynamic properties and driving tracks with different geometries and surface. MADRaS inherits these functionalities from TORCS and introduces support for multi-agent training, inter-vehicular communication, noisy observations, stochastic actions, and custom traffic cars whose behaviors can be programmed to simulate challenging traffic conditions encountered in the real world. MADRaS can be used to create driving tasks whose complexities can be tuned along eight axes in well-defined steps. This makes it particularly suited for curriculum and continual learning. MADRaS is lightweight and it provides a convenient OpenAI Gym interface for independent control of each car. Apart from the primitive steering-acceleration-brake control mode of TORCS, MADRaS offers a hierarchical track-position – speed control mode that can potentially be used to achieve better generalization. MADRaS uses a UDP based client server model where the simulation engine is the server and each client is a driving agent. MADRaS uses multiprocessing to run each agent as a parallel process for efficiency and integrates well with popular reinforcement learning libraries like RLLib. We show experiments on single and multi-agent reinforcement learning with and without curriculum
Научное рецензирование. Лучшие практики и рекомендации
Authors: Spyns Peter , Vidal Maria-Esther 
Published: April 2021

This booklet aims to tackle this problem by providing a practical introduction to the practice of peer reviewing. Although it mainly focuses on paper reviewing for scientific events in the domain of computer science and (business) informatics, many of the principles, tips, tricks, and examples are generalizable to journal reviewing and other scientific domains. Some of the principles and tips can also be applied when reviewing proposals for research projects or grants. In addition, many aspects of this booklet will also benefit authors of scientific papers (even outside computer science) as they will gain more insight into how papers are reviewed and hence where they have to pay attention to when writing their papers.
A cross-sectional study to assess lipid profile & atherogenic index of plasma in premenopausal & post menopausal women in rural Telangana
Authors: Jabeen Ayesha , Rahman Amtul , Ravirala Tagore 
Published: April 2021

: Menopause is associated with various hormonal changes which are accountable for the dyslipidemic pattern seen in postmenopausal women. This deranged lipid profile in postmenopausal women is indicative of their susceptibility to various cardiovascular diseases.: The aim of the study is to estimate and compare serum lipid profile and Atherogenic index of plasma (AIP) among premenopausal and postmenopausal women.: A cross-sectional study was conducted at Mahavir institute of medical sciences (MIMS), Vikarabad for a period of 3 months.Fasting samples were collected from 100 healthy female volunteers of which 50 were premenopausal women and the other 50 were postmenopausal women. Lipid profile was performed on all samples and AIP was calculated.Carried out in the two groups using paired t tests. Results were expressed as mean ±SD. p value of &#60; 0.05 was considered to be significant.: Total cholesterol (TC), Triglycerides (TAG), Low density lipoprotein (LDL-C) were statistically significantly increased in postmenopausal women as compared to premenopausal women. Atherogenic index plasma (AIP) was elevated in postmenopausal women’s group.Lipid profile screening should be mandatory in postmenopausal women as the hormonal disturbances make them more vulnerable to cardiovascular diseases and its associated complications.
Serum ferritin, lactate dehydrogenase, and gamma glutamyl transferase levels in patients with breast carcinoma
Authors: Mahmood Shaikh , Phaneendra D S Jagannadha , Deepak C S N 
Published: April 2021

Cancer also known as malignant neoplasm, is a broad group of various diseases. In cancer, cells divide and grow uncontrollably, forming malignant tumours, and invade nearby parts of the body. There are over 200 different known cancers that afflict humans. Malignant neoplastic lesions are the eighth leading cause accounting for 6.7% of the total medically certified deaths in India. Breast cancer is by far the most frequent cancer among women with an estimated 2.58 million new cancer cases diagnosed in 2019 (23% of all cancers), and ranks second overall (10.9% of all cancers). It is now the most common cancer both in developed and developing regions with around 690000 new cases estimated in each region (population ratio1:4). Breast cancer is the Most Common cancer in all urban areas in India, and 2nd most common in the rural areas. The most recent data Population Based Cancer Registry PBCR 2016 - 2018 tells us that breast cancer accounts for 25% to 31% of all cancers in women in cities(Mumbai, Delhi, Chennai, Ahmedabad, Bengaluru, Bhopal etc.). Breast cancer alone accounts for around 14% of total female neoplasm deaths.
Study of thyroid profile in relation to glycemic control in type 2 diabetes mellitus patients
Authors: Anveetha Penugonda , Krishna Chittimoju Vamsi 
Published: April 2021

Diabetes mellitus is an endocrine metabolic disorder that causes significant morbidity and mortality around the world. Thyroid gland dysfunction is a significant problem in diabetic patients. In diabetics, hypothyroidism is the most common thyroid abnormality. When compared to healthy people, diabetic patients have a higher incidence of thyroid abnormalities. Diabetes mellitus treatment can be complicated due to irregular thyroid activity.A total of 120 people were studied, with 60 patients with type 2 diabetes mellitus (Cases group) and 60 healthy people (Control group). Patients with and without strong diabetic control are represented in 60 cases. Both subjects had their fasting venous blood samples taken. In both the cases and control groups, fasting blood sugar, HbA1c, serum T3 (Triiodothyronine), serum T4 (Thyroxine), and serum TSH (Thyroid-stimulating hormone) were measured.The thyroid abnormality was significantly seen in diabetic patients when compared to healthy individuals. The abnormality was more significant in patients with poor glycemic control. When comparing cases to controls, mean serum TSH levels were significantly higher, whereas mean serum T3 and T4 levels were significantly lower.Thyroid hormone levels in type 2 diabetics are abnormal due to a change in the hypothalamic–pituitary–thyroid axis. This in turn produces significant metabolic disturbances. This is more significant in diabetics with poor glycemic control. Routine screening for thyroid function should be done in diabetics, which helps in preventing complications. This contributes to improved treatment by lowering morbidity and improving quality of life.
Development of NCOVID-19 Colloidal Gold Immunochromatographic Test Strip
Authors: Liu Wenyi , Li Zhaohua 
Published: April 2021

<div><p>Purpose: To establish a fast, simple and accurate method and immunoassay test card for the detection of new coronavirus (nCOVID-19) antigen. Methods: In this study, colloidal gold immunochromatography technology was used to detect nCOVID-19 virus antigens through the sandwich method. At the same time, the preparation plan of colloidal gold was improved, and the application of rapid immune-diagnosis technology in other fields was developed. In this study, purified recombinant nCOVID-19 nucleocapsid protein is used as the antigen to prepare murine monoclonal antibodies. The BN02 antibody produced by the mouse is used as the detection antibody to couple with colloidal gold, forming a gold-labeled complex probe. BN9m1 is used as the coating antibody for the C-line, and ProA is used for the T-line. The polymerization of colloidal gold particles enables us to detect the new coronavirus antigen’s appearance. Thus an in vitro rapid detection kit for virus detection can be made. Results: The positive detection rate of the antigen quality control serum with this colloidal gold reagent was 100%. The specificity was 100%, and the sensitivity was 1ng/ml. Conclusion: The nCOVID-19 antigen detection reagent (colloidal gold method) developed in this research has high specificity and sensitivity, and can be used in conjunction with nucleic acid detection. As a means of detecting nCOVID-19, it can achieve qualitative and rapid screening of samples with advantage such as accuracy, repeatability, and low cost.</p></div>
Sağlık Sektörü Çalışanlarının İletişim Becerilerinin İncelenmesi
Authors: GENÇER ÇELİK Gülşah 
Published: April 2021

Amaç: Bu araştırma kapsamında sağlık çalışanlarının iletişim becerileri açısından profillendirilmesi amaçlanmaktadır.
Tasarım/Yöntem: Araştırma kapsamında İstanbul ilinde hizmet veren iki sağlık kuruluşunda anket çalışması yapılmıştır. 492 sağlık çalışanı araştırmada katılımcı olarak yer almıştır. Verilerin analizinde SPSS 25 paket programı kullanılmıştır. Sağlık çalışanlarının iletişim becerilerinin profillendirilmesi için iki aşamalı kümeleme analizi kullanılmıştır.
Bulgular: Analizler sonucunda; sağlık çalışanlarının üç farklı profile sahip oldukları görülmüştür. Sağlık çalışanlarının iletişim becerilerinin demografik özellikleri açısından farklı profillere ayrıldıkları tespit edilmiştir. Ayrıca çalışanların iletişim becerilerinin düşük düzeyde olduğu sonucuna ulaşılmıştır.
Sınırlılıklar: Araştırma Covid-19 pandemisi esnasında gerçekleştirilmiştir. Bu yüzden farklı bağlamlarda yapılan araştırmalarda sağlık çalışanlarının iletişim becerilerinin daha farklı değerler alabileceği düşünülebilir.
Özgünlük/Değer: İletişim becerileri hakkında yapılan çalışmaların genellikle sağlık çalışanlarının dışındaki örneklemlerde yoğunlaştığı görülmektedir. Bu çalışmada ise sağlık çalışanlarının iletişim becerileri demografik özelliklerle birlikte incelenerek, çalışanların profillerinin belirlenmesi amaçlanmıştır.
Progressing-Cavity-Pump Configuration Addresses Operational Challenges
Authors: Carpenter Chris 
Published: April 2021

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 201130, “Novel Progressing-Cavity-Pump Configurations Address Operational Challenges,” by Lonnie Dunn, SPE, Ryan Rowan, and Abhishek Prakash, Lifting Solution, et al., prepared for the 2020 SPE Virtual Artificial Lift Conference and Exhibition-Americas, 10-12 November. The paper has not been peer reviewed.
While downhole progressing-cavity-pump (PCP) designs provide options for end users, the numerous products available, combined with a lack of industry standardization, can make selection and application challenging. The complete paper provides an overview of the development of a PCP concept and implementation, which is not included in this synopsis, and then summarizes two novel PCP configurations deployed to address specific operational challenges.
Design and Manufacturing, Configuration 1
A novel PCP configuration was developed from phased design trials and experience in cold heavy-oil production with sand (CHOPS) wells. This configuration uses a modified rotor to create alternating sections of contact and noncontact within a conventional stator (Fig. 1). The rotor is landed in the stator and operated until there is a performance decline. Then, the rotor is repositioned to move the active section of the rotor into the areas of the stator where there originally was no contact and, as such, normally no associated damage. Keeping the length of the alternating sections short simplifies the surface rotor positioning process, allowing it to be performed riglessly. The main benefit of this is that, rather than having to pull the rod string and run a different rotor, the same rotor is used and repositioned through lifting of the rod string at surface.
Technology Focus: Formation Damage (March 2021)
Authors: Fleming Niall 
Published: April 2021

Formation damage has received significant attention over many decades, but what about completion damage? Before we discuss this question, we first need to define these terms. Formation damage could be considered as damage to the near-wellbore (e.g., mud solids invasion, plugging). In contrast, completion damage is damage to the lower completion (e.g., plugging of screens). The combined effect of formation and completion damage is the observed well productivity development with associated skin and productivity index. Completion damage has the potential to affect well productivity to the same degree as formation damage. However, at a basic level, there is not even a classification system for completion damage, and yet one has been available for formation damage at least 30 years, possibly longer. Within Equinor, we are trying to address this imbalance by having increased focus on completion damage. We have an ongoing project to develop the following:
A classification system—We have focused on lower completion design and damage that can occur over a well’s lifetime.
A review of testing procedures used and development of new ones where appropriate.
Use of computation fluid dynamics (CFD) more in completion damage evaluations—This approach has provided invaluable new insights. We are using CFD, for example, to visualize displacement efficiency from drilling to completion fluids. We also are incorporating data from coreflooding and completion-damage testing into a single CFD simulation that will enable us to assess what effect formation and completion damage will have on future well productivity.
Whole Genome Sequence of Biosurfactant Producing Bacillus Tequilensis
Authors: Nayarisseri Anuraj , Singh Sanjeev Kumar 
Published: April 2021

Abstract
Background: Bioremediation is crucial for recuperate polluted water and soil. By expanding the surface area of substrates, biosurfactants play a vital role in bioremediation. Bioremediation is crucial for recuperate polluted water and soil. By expanding the surface area of substrates, biosurfactants play a vital role in bioremediation. Biosurfactant producing microbes release certain biosurfactant compounds, which are promoted for oil spill remediation. In the present investigation, a biosurfactant producing bacterium Bacillus tequilensis was isolated from Chilika lake, Odisha, India (latitude and longitude: 19.8450 N 85.4788 E). Whole Genome Sequencing (WGS) of Bacillus tequilensis was carried out using Illumina NextSeq 500.Results: The whole genome sequence is 4.47 MB consisting of 4,478,749 base pairs forming a circular chromosome with 528 scaffolds, 4492 protein-encoding genes(ORFs), 81 tRNA genes, and 114 ribosomal RNA transcription units. The total number of raw reads was 4209415, and processed reads were 4058238 with predicted genes of 4492. The whole-genome obtained from the present investigation was used for genome annotation, variant calling, variant annotation and comparative genome analysis with other existing Bacillus species. In this study, a pathway was constructed which describe the biosurfactant metabolism of Bacillus tequilensis. The study identified genes such as SrfAD, SrfAC, SrfAA, SrfAB which are involved in biosurfactant synthesis. Conclusion: The sequence of the genes SrfAD, SrfAC, SrfAA, SrfAB was deposited in Genbank database with accession MUG02427.1, MUG02428.1, MUG02429.1, MUG03515.1 respectively. The whole-genome sequence was submitted to Genbank with an accession RMVO00000000 and the raw reads can be obtained from SRA, NCBI repository using accession: SRX5023292.
Exploratory analysis of COVID-19 patients usingprincipal component analysis, feature selection andpredictive algorithms
Authors: Carlotti Danilo Panzeri Nogueira , Levin Anna Sara , Buss Lewis , Leite Gabriel Fialkovitz Da Costa , Sabino Ester , Ferreira João Eduardo , Nunes Fátima 
Published: April 2021

Abstract
The novel coronavirus disease (COVID-19) emerged in late 2019 has shown that research done with open data could bethe cornerstone for overcoming the need for collaborative, optimized and urgent analysis. Although several articles have beenpublished, identification of variables that can have correlation with positive PCR results is still a challenge. In this paper weshow a concrete example of open data analysis from 910 patients attended in the hospital undergoing SARS-CoV-2 RT-PCR inthree private institutions in S ̃ao Paulo, Brazil. We performed an exploratory analysis using principal component analysis, featureselection and predictive algorithms to test for associations between a number of laboratory test abnormalities and the SARS-CoV-2 RT-PCR result. More concretely, we found a set of 18 variables that showed some association with a positive PCR result.Among these variables elevated lactic dehydrogenase (LDH) and d-dimer were the most correlated with a positive RT-PCR. Wedeveloped a classifier that achieved 76% mean accuracy, 77% mean precision and 92% mean sensitivity to identify individualswith COVID-19