bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concordance in HPV Detection Between Self-Collected and Health Provider–Collected Cervicovaginal Samples Using careHPV in Tanzanian Women
Authors: Katanga Johnson J. , Rasch Vibeke , Manongi Rachel , Pembe Andrea B. , Mwaiselage Julius D. , Kjaer Susanne K. 
Published: June 2021

PURPOSE Cervical cancer screening is one of the strategies to prevent the disease among women at risk. Human papillomavirus (HPV) DNA testing is increasingly used as the cervical cancer screening method because of its high sensitivity. Self-collection of cervical specimens has the potential to improve participation. However, there is only limited information on comparison between self-collected and provider-collected samples with regard to detection of high-risk HPV using the careHPV method. The study aimed to compare HPV detection by careHPV in self-collected and provider-collected cervical samples and to assess the acceptability of self-collection techniques. MATERIAL AND METHODS Women attending cervical cancer screening clinics at Ocean Road Cancer Institute, Kilimanjaro Christian Medical Centre or Mawenzi Hospital in Tanzania were included in the study. They underwent a face-to-face interview, HIV testing, and collected a self-sample using Evalyn Brush. Subsequently, they had a cervical sample taken by a health provider. Both samples were tested for high-risk HPV DNA using careHPV. RESULTS Overall, 464 women participated in the study. The high-risk HPV prevalence was 19.0% (95% CI, 15.6 to 22.9) in the health provider samples, but lower (13.8%; 95% CI, 10.9 to 17.3) in the self-collected samples. There was a good overall agreement 90.5% (95% CI, 87.5 to 93.0) and concordance (κ = 0.66; 95% CI, 0.56 to 0.75) between the two sets of samples. Sensitivity and specificity were 61.4% (95% CI, 50.4 to 71.6) and 97.3% (95% CI, 95.2 to 98.7), respectively, varying with age. Most women preferred self-collection (79.8%). CONCLUSION Overall, self-sampling seems to be a reliable alternative to health-provider collection and is acceptable to the majority of women. However, instructions on proper procedures for sample collection to the women are important.
Substantial Reduction in Adjuvant Chemotherapy With the Use of the 21-Gene Test to Manage Early Breast Cancer in a Public Hospital in Brazil
Authors: Mattar André , Fonseca Guilherme R. , Romão Murilo B. A. , Shida Jorge Y. , de Oliveira Vilmar M. , Bastos Maria C. S. , Bagnoli Fabio , Rinaldi Jose F. , Stiepcich Monica M. Á. , da Silva Maria A. L. G. , Jakubowski Debbie M. , Chao Calvin , Oliveira Sergio C. , Gebrim Luiz H. 
Published: June 2021

PURPOSE We evaluated the impact of 21-gene test results on treatment decisions for patients with early-stage breast cancer treated under the public health care system in Brazil, Sistema Único de Saúde. METHODS Eligible patients treated at Hospital Pérola Byington and Santa Casa de Misericórdia de São Paulo in Brazil were required to have the following characteristics: postsurgery with hormone receptor–positive, human epidermal growth factor 2–negative, node-negative and node-positive, and T1/T2 breast cancer and patients with these characteristics were candidates for adjuvant systemic therapy. Treatment recommendations, chemotherapy plus hormonal therapy (CT + HT) or HT alone, were captured before and after 21-gene test results. RESULTS From August 2018 to April 2019, 179 women were enrolled. The mean age was 58 years (29-86 years), 135 (76%) were postmenopausal, and 58 (32%) had node-positive breast cancer. Most patients (61%) had a tumor > 2 cm, including 7% with tumors > 4 cm. Using Recurrence Score (RS) result cut points on the basis of the TAILORx trial, 40 (22%) had RS 0-10, 91 (51%) had RS 11-25, and 48 (27%) had RS 26-100. Before 21-gene testing, 162 of 179 (91%) patients were recommended for CT. After testing, 117 of 179 patients (65%) had changes in CT recommendation: 112 (63%) who were initially recommended CT received HT alone and five (3%) who were initially recommended HT alone received CT + HT. After 21-gene testing, 99% of physicians reported strong confidence in their treatment recommendations. CONCLUSION The change in clinical practice at these public hospitals was greater than expected: 66% of initial treatment recommendations were changed to omit CT with 21-gene test results. Clinicopathologic features did not correlate well with 21-gene test results and did not adequately identify those most likely to benefit from CT.
Flipped, Broken, and PausedClave
Authors: Simpson-Litke Rebecca 
Published: June 2021

AbstractThis article examines some of the complex interactions between salsa music and dance by focusing on physical interpretations of specific types of metric ambiguities and disruptions. It explores both the fairly frequent displacement dissonances that arise when the established clave pattern is flipped, paused, or broken and the grouping dissonances that are somewhat rare occurrences in salsa music, showing how dancers' responses to these metric disruptions depend heavily on the unique features of each musical context. Annotated videos break down salsa's fundamental dance and musical structures, encouraging readers to contemplate the artful interpretations presented by experienced dance practitioners and to engage with these interesting musical passages more intimately by trying out the dance steps for themselves.
Music in the Body
Authors: Stevens Alison 
Published: June 2021

AbstractDance in general and the contredanse in particular have long been recognized as important to eighteenth-century European music. But music theorists have tended to understate the contredanse's unique contribution, when they haven't overlooked it entirely: dances are more often treated as musical styles or topics than as movement patterns, and the minuet, with more explicit connections to art music, has received more attention than the contredanse. This article analyzes the choreography as well as the music of eighteenth-century contredanses to show how this dance supported the development of hypermetrical hearing. The contredanse had surpassed the minuet in popularity by the second half of the eighteenth century, probably in part because of its participatory rather than performative nature. More important, it was the first dance in which alignment of choreography and music consistently extended to multiple hypermetric levels. In addressing the importance of contredanse choreography to eighteenth-century hypermeter, this article makes a broader appeal for incorporation of dance and the body into the study of meter.
Panel Data in Research on Mobility and Migration: A Review of Recent Advances
Authors: Vidal Sergi , Lersch Philipp M. 
Published: June 2021

Panel data has become the gold standard for causal assessments of complex human behaviour in quantitative social science. The objective of this review is to examine and discuss how panel data and related methods contribute to the identification of causal relationships in spatial mobility research. We illustrate this by providing a succinct overview of recent progress in spatial mobility research, drawing on panel data. The review outlines research from a number of scholarly disciplines that maps patterns, establishes determinants and assesses the impact of spatial mobility for a range of outcomes. Studies presented in this article are used to decipher complex interdependencies over the life course, scrutinise the selectivity of migrants, and shed light on the interplay between individual agency, social embeddedness and socio-structural contexts. The article concludes with a set of critical issues for future research.
* This article belongs to a special issue on "Identification of causal mechanisms in demographic research: The contribution of panel data".
Optimal microbiological sampling for the diagnosis of osteoarticular infection
Authors: Sousa Ricardo , Carvalho André , Santos Ana Cláudia , Abreu Miguel Araújo 
Published: June 2021

Infection is a dire complication afflicting every field of orthopaedics and traumatology. If specific clinical, laboratory and imaging parameters are present, infection is often assumed even in the absence of microbiological confirmation. However, apart from confirming infection, knowing the exact infecting pathogen(s) and their antimicrobial susceptibility patterns is paramount to help guide treatment. Every effort should therefore be undertaken with that goal in mind. Not all microbiological findings carry the same relevance, and knowing exactly how and where a sample was collected is key. Several different sampling techniques are available, and one must be aware of both advantages and limitations. Microbiological sampling alternatives in some of the most common clinical scenarios such as native and prosthetic joint infections, osteomyelitis and fracture-related infections, spinal and diabetic foot infections will be discussed. Orthopaedic surgeons should also be aware of basic laboratory sample processing techniques as they have a direct impact on the way specimens should be dealt with and transported to the laboratory. Only by knowing these basic principles will surgeons be able to participate in the multidisciplinary discussion and decision making around how to interpret microbiological findings in each specific patient.Cite this article: EFORT Open Rev 2021;6:390-398. DOI: 10.1302/2058-5241.6.210011
The use of ‘blocking’ screws for the ‘closed’ reduction of difficult proximal and distal femoral fractures
Authors: Garnavos Christos 
Published: June 2021

Most meta-diaphyseal femoral fractures that are treated with intramedullary nailing can be reduced satisfactorily by skeletal traction without ‘opening’ the fracture site and therefore, complications such as nonunion, infection and wound healing problems are reduced. In cases where adequate fracture reduction cannot be achieved by skeletal traction, ‘reduction aids’ have been used during the operative procedure in order to avoid the exposure of the fracture site. The ‘blocking’ screw, as a reduction tool, was proposed initially for the ‘difficult’ metaphyseal fractures of the tibia. Subsequently, surgeons have tried to implement the ‘blocking’ screw technique in ‘difficult’ distal femoral fractures. This article presents the ‘blocking’ screw technique as an adjunctive process in the management of fractures of the proximal and distal femur which are found to be non-reducible by skeletal traction alone. The minimal invasiveness of the technique contributes greatly to the preservation of both the soft tissue integrity and the fracture haematoma and thus reduces the major complications that can occur by exposing the fracture site.Cite this article: EFORT Open Rev 2021;6:451-458. DOI: 10.1302/2058-5241.6.210024
Laboratory X-ray interferometry imaging with a fan-shaped source grating
Authors: Shi Zhitian , Jefimovs Konstantins , Romano Lucia , Vila-Comamala Joan , Stampanoni Marco 
Published: June 2021

The orientation mismatch between the cone beam of an X-ray tube and the grating lines in a flat substrate remains a big challenge for laboratory grating-based X-ray interferometry, since it severely limits the imaging field of view. Here, we fabricated fan-shaped

G

0

source gratings by modulating the electric field during the deep reactive ion etching of silicon. The gold electroplated fan-shaped

G

0

grating (3.0 µm pitch) in a 20 keV interferometer improves the uniformity of the field of view with an increase of average visibility from 16.2% to 18.5% and a better angular sensitivity (by a factor 5.8) at the edges.
Locally excited surface plasmon resonance for refractive index sensing with high sensitivity and high resolution
Authors: Wang Xue , Wang Chang , Sun Xiaojuan , Li Xin , Liu Hongyao , Sun Xuqing , Wang Fei , Lu Xinchao , Huang Chengjun 
Published: June 2021

An angle-interrogated surface plasmon resonance (SPR) sensor based on a prism-coupled configuration has been extensively applied in biomedicine, environment monitoring, and food safety. Yet, the low sensitivity and low spatial resolution impede its further development. In this Letter, we investigated objective-coupled locally excited SPR for refractive index (RI) sensing with high sensitivity and high resolution. Through theoretical analysis, the SPR angle was retrieved from back focal plane imaging, which was highly correlated to the RI of the surrounding medium. Experimentally, a RI sensitivity of 77.41° refractive index unit

(

R
I
U

)

−
1

was achieved with a detection range of 0.068 RIU when using glucose solutions for the demonstration. Furthermore, we acquired the spatial resolution of the configuration being 290 nm, and the RI measurement to a polydimethylsiloxane droplet with high spatial resolution was implemented. As a result, compared with the classical prism-coupled configuration, the locally excited SPR provides a method to achieve RI sensing with high sensitivity and high resolution.
Mode-locked all-PM Nd-doped fiber laser near 910  nm
Authors: Le Corre Kilian , Robin Thierry , Cadier Benoit , Becheker Rezki , Godin Thomas , Hideur Ammar , Gilles Hervé , Girard Sylvain , Laroche Mathieu 
Published: June 2021

We present a compact passively mode-locked fiber laser emitting near 910 nm with an all-polarization-maintaining fiber laser architecture. The ring-cavity laser configuration includes a core-pumped neodymium-doped fiber as a gain medium and a semiconductor saturable absorber mirror as a passive mode-locking element. A bandpass filter is used to suppress parasitic emission near 1.06 µm and allows wavelength tuning between 903 and 912 nm. The laser operates in a highly stable and self-starting all-normal-dispersion regime with a minimum pulse duration of 8 ps at 28.2 MHz pulse repetition rate and 0.2 nJ maximum pulse energy. A single-pass amplifier stage increases the pulse energy up to 1.5 nJ, and pulse compression with a pair of gratings is demonstrated with nearly Fourier transform limited pulses.
The diagnostic value of skin biopsies in Sneddon syndrome
Authors: Starmans N. L. P. , Zoetemeyer S. , van Dijk M. R. , Kappelle L. J. , Frijns C. J. M. 
Published: June 2021

Background
Sneddon syndrome (SS) is defined by widespread livedo reticularis (LR) and stroke. There is no single diagnostic test for SS and diagnosis can be solely based on clinical features. This cross-sectional case-control study aimed to determine the diagnostic value of skin biopsies in SS patients.

Materials and methods
We studied skin biopsies from patients with a clinical diagnosis of SS or isolated LR. We also studied controls with vitiligo or normal skin. Biopsies were considered standardized if 3 biopsies were taken from the white centre of the livedo and reached until the dermis-subcutis border. Biopsies were scored for features of an occlusive microangiopathy without knowledge of the clinical features. Sensitivity and specificity of the biopsy findings were calculated with the clinical criteria as the reference standard.

Results
We included 34 SS patients, 14 isolated LR patients and 41 control patients. Biopsies of 17 patients with SS (50%), 4 with isolated LR (31%) and 10 control patients (24%) showed at least one artery in the deep dermis with a thickened vessel wall combined with recanalization or neovascularization (sensitivity 50% and specificity 69% with LR as reference). Standardized biopsies increased the sensitivity to 70%. In a post hoc analysis the combination of an occlusive microangiopathy and the presence of a livedo pattern in the superficial dermis increased the specificity to 92%.

Conclusions
Standardized skin biopsies can support the clinical diagnosis of SS. An occlusive microangiopathy as the only positive criterion for the diagnosis of SS had insufficient specificity for a definite diagnosis.
Resection of isolated brain metastases in non-small cell lung cancer (NSCLC) patients – evaluation of outcome and prognostic factors: A retrospective multicenter study
Authors: Fuchs Julia , Früh Martin , Papachristofilou Alexandros , Bubendorf Lukas , Häuptle Pirmin , Jost Lorenz , Zippelius Alfred , Rothschild Sacha I. 
Published: June 2021

Background and objectives
Brain metastases occur in about 30% of all patients with non-small cell lung cancer (NSCLC). In selected patients, long-term survival can be achieved by resection of brain metastases. In this retrospective study, we investigate the prognosis of NSCLC patients with resected brain metastases and possible prognostic factors.

Methods
In 119 patients with NSCLC and resected brain metastases, we report the following parameters: extent of resection, resection status, postoperative complications and overall survival (OS). We used the log-rank test to compare unadjusted survival probabilities and multivariable Cox regression to investigate potential prognostic factors with respect to OS.

Results
A total of 146 brain metastases were resected in 119 patients. The median survival was 18.0 months. Postoperative cerebral radiotherapy was performed in 86% of patients. Patients with postoperative radiotherapy had significantly longer survival (median OS 20.2 vs. 9.0 months, p = 0.002). The presence of multiple brain metastases was a negative prognostic factor (median OS 13.5 vs. 19.5 months, p = 0.006). Survival of patients with extracerebral metastases of NSCLC was significantly shorter than in patients who had exclusively brain metastases (median OS 14.0 vs. 23.1 months, p = 0.005). Both of the latter factors were independent prognostic factors for worse outcome in multivariate analysis.

Conclusions
Based on these data, resection of solitary brain metastases in patients with NSCLC and controlled extracerebral tumor disease is safe and leads to an overall favorable outcome. Postoperative radiotherapy is recommended to improve prognosis.
Pricing Dynamics and Solvency in Insurance: Capital Allocation, Surplus and Insurance Cycle
Authors: Sanou Adama , Soumaré Issouf 
Published: June 2021

AbstractThis paper proposes a stochastic multi-period pricing model based on the default option value with insurance cycle to examine the interactions among pricing, surplus allocation and solvency for a multiline insurer. The proposed innovative model captures the dynamic aspects of capitalization and the impact of dynamic premium setting on the insurer’s solvency and risk management. We derived the equilibrium premium for different insurance contract designs. Our results show that the allocation of surplus per line affects the default of the other lines and depends on the correlation between the solvency ratio and the loss ratio of the line. The presence of the insurance cycle can boost solvency provided that the insurer adopts the right underwriting strategy. Based on the correlation between the solvency ratio and the loss ratio of the line, the insurer can make strategic decision about fair pricing. This makes it possible to reconcile the objectives of pricing with the insurer’s solvency and its strategic decision-making in a long-term perspective.
Some References to Visualization Practices in Early Chán Buddhism with an Emphasis on guān 觀 and kàn 看
Authors: Anderl Christoph 
Published: June 2021

Abstract
In the analysis of processes of sensory perception in the framework of Buddhist contemplation practices, the visual sense faculty has played a crucial role. In this paper, references to Chinese Buddhist terminology referring to visual processes will be analyzed in their historical context, with a focus on the interpretations of guān 觀 and kàn 看 by proponents of the early Chán School. Crucial questions include the notions of the “agent” (i.e., the entity engaging in the process of visualization or viewing), as well as the ontological status of the “object” to be viewed, in addition to the nature of the process of viewing and the bodily preconditions for engaging in visualization practices. The creative reinterpretations of terms such as guānxīn 觀心 “contemplate the mind” and kànxīn 看心 “view the mind” were also important devices to create a distinctive identity for this newly emerging Chinese Buddhist school. As will be shown, despite the fierce attacks on “gradualist” meditation practices by proponents of the “Southern School” of Chán during the 8th century, the concepts of guānxīn and kànxīn by no means disappeared from the discourse on meditation but continued to play an important role at least until the 10th century and beyond.
Game Theory Without Partitions, and Applications to Speculation and Consensus
Authors: Geanakoplos John 
Published: June 2021

Abstract
Decision theory and game theory are extended to allow for information processing errors. This extended theory is then used to reexamine market speculation and consensus, both when all actions (opinions) are common knowledge and when they may not be. Five axioms of information processing are shown to be especially important to speculation and consensus. They are called nondelusion, knowing that you know (KTYK), nested, balanced, and positively balanced. We show that it is necessary and sufficient that each agent's information processing errors be (1) nondeluded and balanced so that the agents cannot agree to disagree, (2) nondeluded and positively balanced so that it cannot be common knowledge that they are speculating, and (3) nondeluded and KTYK and nested so that agents cannot speculate in equilibrium. Each condition is strictly weaker than the next one, and the last is strictly weaker than partition information.
From the herringbone dome by Sangallo to the Serlio floor of Emy (and beyond)
Authors: Roberti Giulio Mirabella , Ruscica Giuseppe , Paris Vittorio 
Published: June 2021

Abstract
The research starts from an analogy found between two apparently very different structural solutions: the double spiral pattern of the herringbone brick courses in the domes built by Antonio da Sangallo the Younger (1484-1546) during the Renaissance, and the particular pattern of a wooden floor ‘à la Serlio’, described by Amand Rose Emy in his Treatise at the beginning of 19th century, made by diagonal beams reciprocally sustained. The diagonal pattern of the floor has a geometrical relationship with the cross-herringbone pattern, so that the latter can be obtained by some geometrical transformations of the former. This pattern was also used in thin shells built by Nervi, from the destroyed airplane hangars in Tuscany to the Palazzetto dello sport in Rome, and even by Piacentini in 1936 and earlier in some neoclassical domes. Thus the construction tool, useful for building domes without expensive scaffolding, could have a structural role at the completed construction stage. Within the research different structures were investigated, in order to observe the relevance of this peculiar structural scheme particularly in the construction of modern domes.
Global and local properties of finite groups with only finitely many central units in their integral group ring
Authors: Bächle Andreas , Caicedo Mauricio , Jespers Eric , Maheshwary Sugandha 
Published: June 2021

AbstractThe aim of this article is to explore global and local properties of finite groups whose integral group rings have only trivial central units, so-called cut groups. For such a group, we study actions of Galois groups on its character table and show that the natural actions on the rows and columns are essentially the same; in particular, the number of rational-valued irreducible characters coincides with the number of rational-valued conjugacy classes. Further, we prove a natural criterion for nilpotent groups of class 2 to be cut and give a complete list of simple cut groups. Also, the impact of the cut property on Sylow 3-subgroups is discussed. We also collect substantial data on groups which indicates that the class of cut groups is surprisingly large. Several open problems are included.