bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diet cost and quality using the Healthy Eating Index-2015 in adults from urban and rural areas of Mexico
Authors: Curi-Quinto Katherine , Unar-Munguía Mishel , Rodríguez-Ramírez Sonia , Röös Elin , Willett Walter C , Rivera Juan A 
Published: November 2021

AbstractObjective:To assess the association between diet cost and quality by place of residence.Design:We analysed cross-sectional data of the National Health and Nutrition Survey-2012. Diet cost was estimated by linking dietary data, obtained from a 7-d SFFQ, with municipality food prices, which were derived from a national expenditure survey. Diet quality was assessed using the Healthy Eating Index-2015 (HEI-2015). Association between quintiles of diet cost and HEI-2015 was assessed using linear regression analysis.Settings:Mexico.Participants:2438 adults (18–59 years).Results:Diet cost was positively associated with diet quality (HEI-2015) in urban but not in rural areas. Compared with quintile (Q1) of cost, the increment in diet quality score was 1·17 (95 % CI –0·06, 4·33) for Q2, 2·14 (95 % CI –0·06, 4·33) for Q3, 4·70 (95 % CI 2·62, 6·79) for Q4 and 6·34 (95 % CI 4·20, 8·49) for Q5 (P-trend < 0·001). Individuals in rural v. urban areas on average have higher quality diets at lower cost with higher intakes of whole grains and beans and lower intakes of Na, added sugars and saturated fats. Living in the South, being indigenous and having low socio-economic status were also associated with higher quality diets.Conclusions:Diet cost was positively associated with diet quality, but only in urban areas. Further studies are needed to understand the relation between diet cost and quality in rural areas. To improve overall diet quality in Mexico, strategies that aim to reduce the cost of high-quality diets should consider the heterogeneity by place of residence.
Investigating the Jana Adalat of the 1996–2006 armed conflict in Nepal
Authors: Sangroula Yugichha 
Published: November 2021

AbstractThe Communist Party of Nepal (Maoist) (CPN-M), an organized armed group, engaged in a non-international armed conflict against the Government of Nepal between 1996 and 2006. During the armed conflict, the organized armed group operated a judicial system in the territories under its effective control, called the Jana Adalat (the People's Court). The legitimacy of the Jana Adalat has been a contentious subject matter. This article examines the historical, legal and practical dimensions of the Jana Adalat, especially focusing on the perspectives of the CPN-M.
Polarization sensitive optical coherence tomography with single input for imaging depth-resolved collagen organizations
Authors: Tang Peijun , Kirby Mitchell A. , Le Nhan , Li Yuandong , Zeinstra Nicole , Lu G. Nina , Murry Charles E. , Zheng Ying , Wang Ruikang K. 
Published: November 2021

AbstractCollagen organization plays an important role in maintaining structural integrity and determining tissue function. Polarization-sensitive optical coherence tomography (PSOCT) is a promising noninvasive three-dimensional imaging tool for mapping collagen organization in vivo. While PSOCT systems with multiple polarization inputs have demonstrated the ability to visualize depth-resolved collagen organization, systems, which use a single input polarization state have not yet demonstrated sufficient reconstruction quality. Herein we describe a PSOCT based polarization state transmission model that reveals the depth-dependent polarization state evolution of light backscattered within a birefringent sample. Based on this model, we propose a polarization state tracing method that relies on a discrete differential geometric analysis of the evolution of the polarization state in depth along the Poincare sphere for depth-resolved birefringent imaging using only one single input polarization state. We demonstrate the ability of this method to visualize depth-resolved myocardial architecture in both healthy and infarcted rodent hearts (ex vivo) and collagen structures responsible for skin tension lines at various anatomical locations on the face of a healthy human volunteer (in vivo).
A neuropsychosocial signature predicts longitudinal symptom changes in women with irritable bowel syndrome
Authors: Bhatt Ravi R. , Gupta Arpana , Labus Jennifer S. , Liu Cathy , Vora Priten P. , Jean Stains  , Naliboff Bruce D. , Mayer Emeran A. 
Published: November 2021

AbstractIrritable bowel syndrome (IBS) is a common disorder of brain-gut interactions characterized by chronic abdominal pain, altered bowel movements, often accompanied by somatic and psychiatric comorbidities. We aimed to test the hypothesis that a baseline phenotype composed of multi-modal neuroimaging and clinical features predicts clinical improvement on the IBS Symptom Severity Scale (IBS-SSS) at 3 and 12 months without any targeted intervention. Female participants (N = 60) were identified as “improvers” (50-point decrease on IBS-SSS from baseline) or “non-improvers.” Data integration analysis using latent components (DIABLO) was applied to a training and test dataset to determine whether a limited number of sets of multiple correlated baseline’omics data types, including brain morphometry, anatomical connectivity, resting-state functional connectivity, and clinical features could accurately predict improver status. The derived predictive models predicted improvement status at 3-months and 12-months with 91% and 83% accuracy, respectively. Across both time points, non-improvers were classified as having greater correlated morphometry, anatomical connectivity and resting-state functional connectivity characteristics within salience and sensorimotor networks associated with greater pain unpleasantness, but lower default mode network integrity and connectivity. This suggests that non-improvers have a greater engagement of attentional systems to perseverate on painful visceral stimuli, predicting IBS exacerbation. The ability of baseline multimodal brain-clinical signatures to predict symptom trajectories may have implications in guiding integrative treatment in the age of precision medicine, such as treatments targeted at changing attentional systems such as mindfulness or cognitive behavioral therapy.
HACE1-mediated NRF2 activation causes enhanced malignant phenotypes and decreased radiosensitivity of glioma cells
Authors: Da Chenxing , Pu Jun , Liu Zhe , Wei Jing , Qu Yiping , Wu Yongxing , Shi Bingyin , Yang Jian , He Nongyue , Hou Peng 
Published: November 2021

AbstractHACE1, an E3 ubiquitin-protein ligase, is frequently inactivated and has been evidenced as a putative tumor suppressor in different types of cancer. However, its role in glioma remains elusive. Here, we observed increased expression of HACE1 in gliomas related to control subjects, and found a strong correlation of high HACE1 expression with poor prognosis in patients with WHO grade III and IV as well as low-grade glioma (LGG) patients receiving radiotherapy. HACE1 knockdown obviously suppressed malignant behaviors of glioma cells, while ectopic expression of HACE1 enhanced cell growth in vitro and in vivo. Further studies revealed that HACE1 enhanced protein stability of nuclear factor erythroid 2-related factor 2 (NRF2) by competitively binding to NRF2 with another E3 ligase KEAP1. Besides, HACE1 also promoted internal ribosome entry site (IRES)-mediated mRNA translation of NRF2. These effects did not depend on its E3 ligase activity. Finally, we demonstrated that HACE1 dramatically reduced cellular ROS levels by activating NRF2, thereby decreasing the response of glioma cells to radiation. Altogether, our data demonstrate that HACE1 causes enhanced malignant phenotypes and decreased radiosensitivity of glioma cells by activating NRF2, and indicate that it may act as the role of prognostic factor and potential therapeutic target in glioma.
Breaking down barriers on PV trade will facilitate global carbon mitigation
Authors: Wang Mudan , Mao Xianqiang , Xing Youkai , Lu Jianhong , Song Peng , Liu Zhengyan , Guo Zhi , Tu Kevin , Zusman Eric 
Published: November 2021

AbstractThe global trade of solar photovoltaic (PV) products substantially contributes to increases in solar power generation and carbon emissions reductions. This paper depicts global PV product trade patterns, explores emissions reduction potential, and evaluates the impeding effect of tariff barriers on global PV product trade and emissions reductions. Solar power generation will result in a reduction of emissions in a range of 50–180 gigatons of carbon dioxide equivalent (GtCO2e) between 2017 and 2060 in a business as usual (BAU) scenario. Compared with BAU, during 2017–2060, global total solar cell and module production and installation will increase by roughly 750 gigawatts (GW) if half of the status quo trade barrier are removed, while it will decrease by 160–370 GW under tensioned trade barrier scenarios. Trade barrier reduction by half from the 2017 status quo level will increase the net carbon emissions mitigation potential by 4–12 GtCO2e by 2060, while extra trade barrier imposition will result in global net carbon emissions mitigation potential decreasing by up to 3–4 GtCO2e by 2060. Well-coordinated policy and institutional reforms are recommended to facilitate PV product trade and to deliver the related global environmental benefits.
Listeria monocytogenes faecal carriage is common and depends on the gut microbiota
Authors: Hafner Lukas , Pichon Maxime , Burucoa Christophe , Nusser Sophie H. A. , Moura Alexandra , Garcia-Garcera Marc , Lecuit Marc 
Published: November 2021

AbstractListeria genus comprises two pathogenic species, L. monocytogenes (Lm) and L. ivanovii, and non-pathogenic species. All can thrive as saprophytes, whereas only pathogenic species cause systemic infections. Identifying Listeria species’ respective biotopes is critical to understand the ecological contribution of Listeria virulence. In order to investigate the prevalence and abundance of Listeria species in various sources, we retrieved and analyzed 16S rRNA datasets from MG-RAST metagenomic database. 26% of datasets contain Listeria sensu stricto sequences, and Lm is the most prevalent species, most abundant in soil and host-associated environments, including 5% of human stools. Lm is also detected in 10% of human stool samples from an independent cohort of 900 healthy asymptomatic donors. A specific microbiota signature is associated with Lm faecal carriage, both in humans and experimentally inoculated mice, in which it precedes Lm faecal carriage. These results indicate that Lm faecal carriage is common and depends on the gut microbiota, and suggest that Lm faecal carriage is a crucial yet overlooked consequence of its virulence.
Promoting ethylene production over a wide potential window on Cu crystallites induced and stabilized via current shock and charge delocalization
Authors: Sun Hao , Chen Ling , Xiong Likun , Feng Kun , Chen Yufeng , Zhang Xiang , Yuan Xuzhou , Yang Baiyu , Deng Zhao , Liu Yu , Rümmeli Mark H. , Zhong Jun , Jiao Yan , Peng Yang 
Published: November 2021

AbstractElectrochemical CO2 reduction (CO2RR) in a product-orientated and energy-efficient manner relies on rational catalyst design guided by mechanistic understandings. In this study, the effect of conducting support on the CO2RR behaviors of semi-conductive metal-organic framework (MOF) — Cu3(HITP)2 are carefully investigated. Compared to the stand-alone MOF, adding Ketjen Black greatly promotes C2H4 production with a stabilized Faradaic efficiency between 60-70% in a wide potential range and prolonged period. Multicrystalline Cu nano-crystallites in the reconstructed MOF are induced and stabilized by the conducting support via current shock and charge delocalization, which is analogous to the mechanism of dendrite prevention through conductive scaffolds in metal ion batteries. Density functional theory calculations elucidate that the contained multi-facets and rich grain boundaries promote C–C coupling while suppressing HER. This study underlines the key role of substrate-catalyst interaction, and the regulation of Cu crystalline states via conditioning the charge transport, in steering the CO2RR pathway.
Quantum gas magnifier for sub-lattice-resolved imaging of 3D quantum systems
Authors: Asteria Luca , Zahn Henrik P. , Kosch Marcel N. , Sengstock Klaus , Weitenberg Christof 
Published: November 2021

AbstractImaging is central to gaining microscopic insight into physical systems, and new microscopy methods have always led to the discovery of new phenomena and a deeper understanding of them. Ultracold atoms in optical lattices provide a quantum simulation platform, featuring a variety of advanced detection tools including direct optical imaging while pinning the atoms in the lattice1,2. However, this approach suffers from the diffraction limit, high optical density and small depth of focus, limiting it to two-dimensional (2D) systems. Here we introduce an imaging approach where matter wave optics magnifies the density distribution before optical imaging, allowing 2D sub-lattice-spacing resolution in three-dimensional (3D) systems. By combining the site-resolved imaging with magnetic resonance techniques for local addressing of individual lattice sites, we demonstrate full accessibility to 2D local information and manipulation in 3D systems. We employ the high-resolution images for precision thermodynamics of Bose–Einstein condensates in optical lattices as well as studies of thermalization dynamics driven by thermal hopping. The sub-lattice resolution is demonstrated via quench dynamics within the lattice sites. The method opens the path for spatially resolved studies of new quantum many-body regimes, including exotic lattice geometries or sub-wavelength lattices3–6, and paves the way for single-atom-resolved imaging of atomic species, where efficient laser cooling or deep optical traps are not available, but which substantially enrich the toolbox of quantum simulation of many-body systems.
Assemblage of indigenous arbuscular mycorrhizal fungi and green waste compost enhance drought stress tolerance in carob (Ceratonia siliqua L.) trees
Authors: Boutasknit Abderrahim , Baslam Marouane , Ait-El-Mokhtar Mohamed , Anli Mohamed , Ben-Laouane Raja , Ait-Rahou Youssef , Mitsui Toshiaki , Douira Allal , El Modafar Cherkaoui , Wahbi Said , Meddich Abdelilah 
Published: November 2021

AbstractIn the current study, an eco-friendly management technology to improve young carob (Ceratonia siliquaL.) tree tolerance to water deficit was set up by using single or combined treatments of arbuscular mycorrhizal fungi (AMF) and/or compost (C). Two groups of young carob have been installed: (i) carob cultivated under well-watered conditions (WW; 70% field capacity (FC)) and (ii) where the plants were drought-stressed (DS; 35% FC) during 2, 4, 6, and 8 months. The effect of used biofertilizers on the course of growth, physiological (photosynthetic traits, water status, osmolytes, and mineral content), and biochemical (hydrogen peroxide (H2O2), oxidative damage to lipids (malondialdehyde (MDA), and membrane stability (MS)) traits in response to short- and long-term droughts were assessed. The dual application of AMF and C (C + AMF) boosted growth, physiological and biochemical parameters, and nutrient uptake in carob under WW and DS. After eight months, C + AMF significantly enhanced stomatal conductance by 20%, maximum photochemical efficiency of PSII by 7%, leaf water potential by 23%, chlorophyll and carotenoid by 40%, plant uptake of mineral nutrients (P by 75%, N by 46%, K+by 35%, and Ca2+by 40%), concentrations of soluble sugar by 40%, and protein content by 44% than controls under DS conditions. Notably, C + AMF reduced the accumulation of H2O2and MDA content to a greater degree and increased MS. In contrast, enzyme activities (superoxide dismutase, catalase, peroxidase, and polyphenoloxidase) significantly increased in C + AMF plants under DS. Overall, our findings suggest that the pairing of C + AMF can mediate superior drought tolerance in young carob trees by increasing leaf stomatal conductance, cellular water content, higher solute concentration, and defense response against oxidative damage during the prolonged period of DS.
Responses of different functional tests in candidates for bariatric surgery and the association with body composition, metabolic and lipid profile
Authors: Ricci Paula Angélica , André Larissa Delgado , Jürgensen Soraia Pilon , de Oliveira Claudio Ricardo , Ortega Fernando Pinheiro , Di Thommazo-Luporini Luciana , Borghi-Silva Audrey 
Published: November 2021

AbstractIndividuals with obesity can have metabolic disorders and may develop impairments that affect the ability to exercise. The maximal incremental cardiopulmonary exercise test is widely used to assess functional capacity. However, submaximal tests such as the two-minute step test (2MST) and the six-minute walk test (6MWT) also allow this assessment. We propose to analyze whether body composition, metabolic and lipid profile influence the maximal and submaximal performance, and investigate these variables in response to different functional tests. Forty-four individuals with obesity, aged 18–50 years, underwent analysis of body composition, metabolic and lipid profile, incremental treadmill test (ITMT), 6MWT, and 2MST. One-way ANOVA, Pearson or Spearman correlation, and Stepwise multiple linear regression analysis were performed. ITMT induced a greater metabolic, ventilatory, cardiovascular, and perceived exertion demand when compared to the 6MWT and 2MST (p < 0.05). In addition, 2MST elicited a higher chronotropic (HR) and metabolic (V̇O2) demand when compared to the 6MWT (p < 0.05). Significant correlations were found between tests and body composition, metabolic and lipid profile. Fat mass and low-density lipoprotein can explain 30% of the V̇O2 variance in the ITMT; and fat mass, glucose, and performance in the 2MST can explain 42% of the variance of the distance walked in the ITMT. Obesity and its metabolic impairments are capable of influencing responses to exercise. ITMT generated greater demand due to the high stress imposed, however, 2MST demanded greater metabolic and chronotropic demand when compared to the 6MWT.
Structural insights into bifunctional thaumarchaeal crotonyl-CoA hydratase and 3-hydroxypropionyl-CoA dehydratase from Nitrosopumilus maritimus
Authors: Destan Ebru , Yuksel Busra , Tolar Bradley B. , Ayan Esra , Deutsch Sam , Yoshikuni Yasuo , Wakatsuki Soichi , Francis Christopher A. , DeMirci Hasan 
Published: November 2021

AbstractThe ammonia-oxidizing thaumarchaeal 3-hydroxypropionate/4-hydroxybutyrate (3HP/4HB) cycle is one of the most energy-efficient CO2 fixation cycles discovered thus far. The protein encoded by Nmar_1308 (from Nitrosopumilus maritimus SCM1) is a promiscuous enzyme that catalyzes two essential reactions within the thaumarchaeal 3HP/4HB cycle, functioning as both a crotonyl-CoA hydratase (CCAH) and 3-hydroxypropionyl-CoA dehydratase (3HPD). In performing both hydratase and dehydratase activities, Nmar_1308 reduces the total number of enzymes necessary for CO2 fixation in Thaumarchaeota, reducing the overall cost for biosynthesis. Here, we present the first high-resolution crystal structure of this bifunctional enzyme with key catalytic residues in the thaumarchaeal 3HP/4HB pathway.
Active strategies for multisensory conflict suppression in the virtual hand illusion
Authors: Lanillos Pablo , Franklin Sae , Maselli Antonella , Franklin David W. 
Published: November 2021

AbstractThe perception of our body in space is flexible and manipulable. The predictive brain hypothesis explains this malleability as a consequence of the interplay between incoming sensory information and our body expectations. However, given the interaction between perception and action, we might also expect that actions would arise due to prediction errors, especially in conflicting situations. Here we describe a computational model, based on the free-energy principle, that forecasts involuntary movements in sensorimotor conflicts. We experimentally confirm those predictions in humans using a virtual reality rubber-hand illusion. Participants generated movements (forces) towards the virtual hand, regardless of its location with respect to the real arm, with little to no forces produced when the virtual hand overlaid their physical hand. The congruency of our model predictions and human observations indicates that the brain-body is generating actions to reduce the prediction error between the expected arm location and the new visual arm. This observed unconscious mechanism is an empirical validation of the perception–action duality in body adaptation to uncertain situations and evidence of the active component of predictive processing.
Multifragmentary patellar fracture has a distinct fracture pattern which makes coronal split, inferior pole, or satellite fragments
Authors: Cho Jae-Woo , Yang Zepa , Lim Eic Ju , Sakong Seungyeob , Choi Wonseok , Son Whee Sung , Kim Hanju , Chang An Seong , Lim Do-Young , Kim Youngwoo , Kim Beom-Soo , Oh Jong-Keon 
Published: November 2021

AbstractThe present study aimed to map the location and frequency of fracture lines on the coronal articular and sagittal planes in multifragmentary patellar fractures. 66 multifragmentary patellar fractures were digitally reconstructed using the 3D CT mapping technique. The coronal articular surface and midsagittal fracture maps were produced by superimposing each case over a single template. Each fracture line was classified based on the initial displacement and orientation. We evaluated the frequency and direction of the fracture line, coronal split fragment area, and satellite and inferior pole fragment presence. Coronal articular surface fracture mapping identified primary horizontal fracture lines between the middle and inferior one-third of the articular surface in 63 patients (95.4%). Secondary horizontal fracture lines running on the inferior border of the articular facet were confirmed (83.3%). Secondary vertical fracture lines creating satellite fragments were mostly located on the periphery of the bilateral facet. Midsagittal fracture mapping of primary and secondary horizontal fracture lines with the main coronal fracture line revealed a predominantly X-shaped fracture map. The consequent coronal split fragment and inferior pole fracture were combined in most cases. In conclusion, the multifragmentary patellar fracture has a distinct pattern which makes coronal split, inferior pole, or satellite fragments.
Mixed convective flow of CNTs nanofluid subject to varying viscosity and reactions
Authors: Hussain Zakir , Hayat Tasawar , Alsaedi Ahmed , Anwar Muhammad Shoaib 
Published: November 2021

AbstractThe addressed work explains SWCNTs (Single walled carbon nanotubnes) and MWCNTs (Multi walled carbon nanotubnes) nanofluid flow under the influences of temperature dependent viscosity and mixed convection. Comparative study of SWCNTs and MWCNTs suspended in base liquid is presented. Further heat and mass transfer are addressed for nanofluid effected by radiation, heat generation/absorption and diffusion species. Mathematical development of problem is taken in cylindrical coordinates. System of highly nonlinear differential equations are constructed via appropriate transformations. The system of equations are tackled numerically by bvp4c MATLAB solver. The findings of the study show that larger volume fraction $$\left( \phi \right)$$

ϕ

contributes to enhance the nanoliquid flow. The velocity by submerging MWCNTs is noted higher than SWCNTs. Furthermore, the relationship between the viscosity variable $$\left( \theta _{r}\right)$$

θ
r

and the temperature is such that the temperature near the surface decreases with increase in $$\left( \theta _{r}\right)$$

θ
r

, while at the same time the temperature away from the surface increases. Subsequently, higher temperature is observed in SWCNTs-liquid compared to the MWCNTs-liquid to the similar values of $$\left( \theta _{r}\right)$$

θ
r

. Further, heat transfer is an increasing function of varying viscosity variable $$\left( \theta _{r}\right)$$

θ
r

.