bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self‐management Behaviors and Anthropometric Indices after Roux‐en‐Y Gastric Bypass
Authors: Sobhani Zahra , Amini Masood , Zarnaghash Maryam , Foroutan Hamid Reza , Mojab Seyed Vahid , Khazraei Hajar , Hosseini Seyed Vahid 
Published: March 2021

AbstractBackgroundThe aim of this study was to correlate the connection between self‐management behaviors and anthropometric indices after Roux‐en‐Y gastric bypass (RYGB).MethodsA sample of 180 patients suffering from obesity were treated with RYGB in 2019; 6 and 18 months after surgery, anthropometric indices, including weight, waist circumference, waist‐ to‐height ratio, body mass index (BMI), and waist‐to‐hip ratio, were gauged, and participants completed the post‐bariatric surgery self‐management behaviors questionnaire.ResultsCorrelation matrix results showed that all anthropometric indices had a significant positive relationship with self‐management behaviors after RYGB; the results of the 18‐month post‐surgical follow‐up exhibited no significant difference between anthropometric indices and self‐management behaviors, 6 and 18 months after surgery.ConclusionTherefore, the more self‐management behaviors increase, the greater decrease in anthropometric indices will happen after RYGB.
A behavioral task for exploring dynamics of communication system in dilemma situations
Authors: Inoue Naoki , Morita Junya 
Published: March 2021

AbstractThis research proposes a behavioral task to demonstrate the process of evolution of human communication systems based on the Machiavellian intelligence hypothesis, claiming that human sophisticated social intelligence such as linguistic ability has been formed through behaviors that maximize self-interest in a competitive social situation. The proposed task was designed as a dilemma game involving messaging to establish Machiavellian communication. The game was developed based on experimental semiotics, a method that generates novel artificial language and examines language functions. Through the proposed task, pairs of participants attach meanings to arbitral graphic symbols forming novel communication systems. In case studies using this task, participants modified or ambiguated the communication system by means of a dilemma between sharing and monopolizing rewards. The result suggests that the proposed game causes ambiguation of the communication system that functions equivocally.
The second Hankel determinant for strongly convex and Ozaki close-to-convex functions
Authors: Sim Young Jae , Lecko Adam , Thomas Derek K. 
Published: March 2021

AbstractLet f be analytic in the unit disk $${\mathbb {D}}=\{z\in {\mathbb {C}}:|z|<1 \}$$

D
=
{
z
∈
C
:
|
z
|
<
1
}

, and $${{\mathcal {S}}}$$
S
be the subclass of normalized univalent functions given by $$f(z)=z+\sum _{n=2}^{\infty }a_n z^n$$

f

(
z
)

=
z
+

∑

n
=
2

∞

a
n

z
n

for $$z\in {\mathbb {D}}$$

z
∈
D

. We give sharp bounds for the modulus of the second Hankel determinant $$ H_2(2)(f)=a_2a_4-a_3^2$$

H
2

(
2
)

(
f
)

=

a
2

a
4

-

a
3
2

for the subclass $$ {\mathcal F_{O}}(\lambda ,\beta )$$

F
O

(
λ
,
β
)

of strongly Ozaki close-to-convex functions, where $$1/2\le \lambda \le 1$$

1
/
2
≤
λ
≤
1

, and $$0<\beta \le 1$$

0
<
β
≤
1

. Sharp bounds are also given for $$|H_2(2)(f^{-1})|$$

|

H
2

(
2
)

(

f

-
1

)

|

, where $$f^{-1}$$

f

-
1

is the inverse function of f. The results settle an invariance property of $$|H_2(2)(f)|$$

|

H
2

(
2
)

(
f
)

|

and $$|H_2(2)(f^{-1})|$$

|

H
2

(
2
)

(

f

-
1

)

|

for strongly convex functions.
Effects of Ageing on Aortic Circulation During Atrial Fibrillation; a Numerical Study on Different Aortic Morphologies
Authors: Deyranlou Amin , Miller Christopher A. , Revell Alistair , Keshmiri Amir 
Published: March 2021

AbstractAtrial fibrillation (AF) can alter intra-cardiac flow and cardiac output that subsequently affects aortic flow circulation. These changes may become more significant where they occur concomitantly with ageing. Aortic ageing is accompanied with morphological changes such as dilation, lengthening, and arch unfolding. While the recognition of AF mechanism has been the subject of numerous studies, less focus has been devoted to the aortic circulation during the AF and there is a lack of such investigation at different ages. The current work aims to address the present gap. First, we analyse aortic flow distribution in three configurations, which attribute to young, middle and old people, using geometries constructed via clinical data. We then introduce two transient inlet flow conditions representative of key AF-associated defects. Results demonstrate that both AF and ageing negatively affect flow circulation. The main consequence of concomitant occurrence is enhancement of endothelial cell activation potential (ECAP) throughout the vascular domain, mainly at aortic arch and descending thoracic aorta, which is consistent with some clinical observations. The outcome of the current study suggests that AF exacerbates the vascular defects occurred due to the ageing, which increases the possibility of cardiovascular diseases per se.
Coatings with recycled polyvinyl butyral on polyester and polyamide mono- and multifilament yarns
Authors: Brendgen Rike , Graßmann Carsten , Grethe Thomas , Mahltig Boris , Schwarz-Pfeiffer Anne 
Published: March 2021

AbstractPolyvinyl butyral is used in safety glass interlayers, mainly in car windshields. Legislative regulations require a recycling of cars after their lifetime and therefore also their safety glass. This causes the availability of recycled polyvinyl butyrate (r-PVB) originated from safety glass interlayers. Due to deteriorated optical properties, such as the transparency, and unknown amounts of plasticizers, it is challenging to reuse the recycled material in new windshields. Therefore, it is of particular interest to find new fields of application for r-PVB, such as the usage as a textile coating. In this research, r-PVB was investigated as a material for yarn coating. Polyester and polyamide mono- and multifilament yarns were coated continuously with solely a polymer dispersion and with mixtures of crosslinking agent and polymer dispersion. Crosslinked r-PVB coatings showed enhanced properties toward abrasion and chemical resistance. Coatings without the crosslinking agent showed a diminished abrasion resistance and could be washed off with ethanol. Mechanical properties of the monofilaments were influenced by the r-PVB coating in general. However, varying concentrations of the crosslinking agent did not affect the mechanical properties.
Relationship Between Thyroid Hormonal Status in Patients with a Hypothyroid Form of Hashimoto’s Thyroiditis and Iodine Concentrations in Drinking Water
Authors: Kasiyan Olha , Tkachenko Halyna , Kurhaluk Natalia , Yurchenko Svitlana , Manenko Alek 
Published: March 2021

AbstractThe current study aimed to identify correlative and regressive dependencies between the water iodine concentration and the levels of TSH (thyroid-stimulating hormone), thyroglobulin antibodies (TgAbs), and thyroid peroxidase (TPOAb) in the serum of 168 in patients (34 men and 134 women) with a hypothyroid form of Hashimoto’s thyroiditis who use water from the supply network and individual wells. Based on the water iodine concentration, low and moderate degrees of iodine endemia in the location of the patients were determined. In the groups of men and women using water from different water supply sources, there were direct correlations between the water iodine concentrations and the TgAbs and TPOAb titers as well as an inverse dependence between iodine and TSH levels. Multivariate regressive analysis indicated that TgAb and TSH in the group of women using water from a supply network and TPOAb titers in the group of women using well water were independent factors associated with water iodine concentrations. Statistically significant correlations and regressive dependencies between the water iodine concentrations and the biomarkers of the thyroid status of the patients indicate the risk of Hashimoto’s thyroiditis progression, especially among women with additional iodine intake.
Systematic Review and Meta-analysis on the Association of Occupational Exposure to Free Crystalline Silica and Rheumatoid Arthritis
Authors: Morotti A. , Sollaku I. , Franceschini F. , Cavazzana I. , Fredi M. , Sala E. , De Palma G. 
Published: March 2021

Abstract

Key messages

• Occupational exposure to free crystalline silica and tobacco smoking are associated with an increased risk rheumatoid arthritis, with the evidence of an interaction in seropositive subjects.
• Further studies in the field are needed to support such association
We carried out a systematic search for all published epidemiological studies concerning the association between occupational exposure to free crystalline silica (FCS) and subsequent development of rheumatoid arthritis (RA). A meta-analysis was conducted on relevant studies. We searched PubMed and Embase, search engines, for original articles published (from 1960 to November 2019) in any language. In addition, we also searched reference lists of included studies manually for additional relevant articles. Finally, twelve studies were included in the meta-analysis (seven case-control cases and five cohort studies). The odds risks and 95% confidence interval (CI) were calculated using a random effect meta-analysis. A primary meta-analysis (using a random effect model)—regarding RA risk in subjects exposed to FCS—yelled to an overall OR of 1.94 (95% CI 1.46–2.58). We also conducted three further meta-analysis, taking into account the presence of autoantibodies (anti-RF or anti-ACPA) and smoking habits and found a significant association between FCS and RA in both seropositive and seronegative subjects (OR 1.74, 95% CI 1.35–2.25 and OR 1.23, 95% CI 1.06–1.4, respectively) and in seropositive subjects which were smokers (OR 3.30, 95% CI 2.40–4.54). The studies that have investigated the association between RA and occupatational exposure to FCS are still scarce and the heterogeneity between the studies remains high. Some critical limitations have been identified within studies, among which, the methods for assessing exposure stand out. Although with due caution, our results confirm the hypothesis of an association between occupational exposure to FCS and RA development. There was an interaction between FCS and tobacco smoking in RA seropositive workers.
Secondary Hematoma Evacuation and Outcome After Initial Conservative Approach for Patients with Cerebellar Hematoma Larger than 3 cm
Authors: Singh Sanjula D. , Schreuder Floris H. B. M. , van Nieuwenhuizen Koen M. , Jolink Wilmar M. , Senff Jasper R. , Goldstein Joshua N. , Boogaarts Jeroen , Klijn Catharina J. M. , Rinkel Gabriel J. E. , Brouwers H. Bart 
Published: March 2021

Abstract
Background
In patients with spontaneous cerebellar intracerebral hemorrhage (ICH) guidelines advocate evacuation when the hematoma diameter is > 3 cm. We studied outcome in patients with cerebellar ICH > 3 cm who did not undergo immediate hematoma evacuation.

Methods
We included consecutive patients with cerebellar ICH > 3 cm at two academic hospitals between 2008 and 2017. Patients who died < 24 h (h) were excluded because of probable confounding by indication. We determined patient characteristics, hematoma volumes, EVD placement, secondary hematoma evacuation, in-hospital and 3-month case-fatality, and functional outcome.

Results
Of 130 patients with cerebellar ICH, 98 (77%) had a hematoma > 3 cm of whom 22 (23%) died < 24 h and 28 (29%) underwent hematoma evacuation < 24 h. Thus, 48 patients were initially treated conservatively (mean age 70 ± 13, 24 (50%) female). Of these 48 patients, 7 (15%) underwent secondary hematoma evacuation > 24 h, of whom 1 (14%) had received an EVD < 24 h. Five others also received an EVD < 24 h without subsequent hematoma evacuation. Of the 41 patients without secondary hematoma evacuation, 11 (28%) died and 20 (51%) had a favorable outcome (mRS of 0–3) at 3 months. The 7 patients who underwent secondary hematoma evacuation had a decrease in GCS score of at least two points prior to surgery; two (29%) had deceased at 3 months; and 5 (71%) had a good functional outcome (mRS 0–3).

Conclusions
While cerebellar ICH > 3 cm is often considered an indication for immediate hematoma evacuation, there may be a subgroup of patients in whom surgery can be safely deferred. Further data are needed to assess the optimal timing and indications of surgical treatment in these patients.
Effect of the catalyst in the BTX production by hydrocracking of light cycle oil
Authors: Laredo Georgina C. , García-Gutiérrez José L. , Pérez-Romo Patricia , Olmos-Cerda Eli H. 
Published: March 2021

AbstractCatalysts to produce the important petrochemicals like benzene, toluene, and xylene (BTX) from refinery feedstocks, like light cycle oil (LCO) are reviewed here by covering published papers using model mixtures and real feeds. Model compounds experiments like tetralin and naphthalene derivatives provided a 53–55% total BTX yield. Higher yields were never attained due to the inevitable gas formation and other C9+-alkylbenzenes formed. For tetralin, the best catalysts are those conformed by Ni, CoMo, NiMo, or NiSn over zeolite H-Beta. For naphthalene derivatives, the best catalysts were those conformed by W and NiW over zeolite H-Beta silylated. Real feeds produced a total BTX yield of up to 35% at the best experimental conditions. Higher yields were never reached due to the presence of other types of hydrocarbons in the feed which can compete for the catalytic sites. The best catalysts were those conformed by Mo, CoMo, or NiMo over zeolite H-Beta. Some improvements were obtained by adding ZSM-5 to the support or in mixtures with other catalysts.
On mass and matter
Authors: Roberts Craig D. 
Published: March 2021

AbstractThe visible Universe is largely characterised by a single mass scale, namely, the proton mass,mp. Contemporary theory suggests thatmpemerges as a consequence of gluon self-interactions, which are a defining characteristic of quantum chromodynamics (QCD), the theory of strong interactions in the Standard Model. However, the proton is not elementary. Its mass appears as a corollary of other, more basic emergent phenomena latent in the QCD Lagrangian, e.g. generation of nuclear-size gluon and quark mass-scales, and a unique effective charge that may describe QCD interactions at all accessible momentum scales. These remarks are explained herein, and focusing on the distribution amplitudes and functions ofπandKmesons, promising paths for their empirical verification are elucidated. Connected therewith, in anticipation that production ofJ/ψ-mesons usingπandKbeams can provide access to the gluon distributions in these pseudo-Nambu-Goldstone modes, predictions for allπandKdistribution functions are provided at the scaleζ=mJ/ψ.
Structural and Functional Analyses of Hub MicroRNAs in An Integrated Gene Regulatory Network of Arabidopsis
Authors: Gao Zhaoxu , Li Jun , Li Li , Yang Yanzhi , Li Jian , Fu Chunxiang , Zhu Danmeng , He Hang , Cai Huaqing , Li Lei 
Published: March 2021

Abstract
MicroRNAs (miRNAs) are trans-acting small regulatory RNAs that work coordinately with transcription factors (TFs) to shape the repertoire of cellular mRNAs available for translation. Despite our growing knowledge of individual plant miRNAs, their global roles in gene regulatory networks remain mostly unassessed. Based on interactions obtained from public databases and curated from the literature, we reconstructed an integrated miRNA network in Arabidopsis that includes 66 core TFs, 318 miRNAs, and 1712 downstream genes. We found that miRNAs occupy distinct niches and enrich miRNA-containing feed-forward loops (FFLs), particularly those with miRNAs as intermediate nodes. Further analyses revealed that miRNA-containing FFLs coordinate TFs located in different hierarchical layers and that intertwined miRNA-containing FFLs are associated with party and date miRNA hubs. Using the date hub MIR858A as an example, we performed detailed molecular and genetic analyses of three interconnected miRNA-containing FFLs. These analyses revealed individual functions of the selected miRNA-containing FFLs and elucidated how the date hub miRNA fulfills multiple regulatory roles. Collectively, our findings highlight the prevalence and importance of miRNA-containing FFLs, and provide new insights into the design principles and control logics of miRNA regulatory networks governing gene expression programs in plants.
Chinese Glioma Genome Atlas (CGGA): A Comprehensive Resource with Functional Genomic Data from Chinese Glioma Patients
Authors: Zhao Zheng , Zhang Ke-Nan , Wang Qiangwei , Li Guanzhang , Zeng Fan , Zhang Ying , Wu Fan , Chai Ruichao , Wang Zheng , Zhang Chuanbao , Zhang Wei , Bao Zhaoshi , Jiang Tao 
Published: March 2021

Abstract
Gliomas are the most common and malignant intracranial tumors in adults. Recent studies have revealed the significance of functional genomics for glioma pathophysiological studies and treatments. However, access to comprehensive genomic data and analytical platforms is often limited. Here, we developed the Chinese Glioma Genome Atlas (CGGA), a user-friendly data portal for the storage and interactive exploration of cross-omics data, including nearly 2000 primary and recurrent glioma samples from Chinese cohort. Currently, open access is provided to whole-exome sequencing data (286 samples), mRNA sequencing (1018 samples) and microarray data (301 samples), DNA methylation microarray data (159 samples), and microRNA microarray data (198 samples), and to detailed clinical information (age, gender, chemoradiotherapy status, WHO grade, histological type, critical molecular pathological information, and survival data). In addition, we have developed several tools for users to analyze the mutation profiles, mRNA/microRNA expression, and DNA methylation profiles, and to perform survival and gene correlation analyses of specific glioma subtypes. This database removes the barriers for researchers, providing rapid and convenient access to high-quality functional genomic data resources for biological studies and clinical applications. CGGA is available at http://www.cgga.org.cn.
Robust Benchmark Structural Variant Calls of an Asian Using State-of-the-Art Long-Read Sequencing Technologies
Authors: Du Xiao , Li Lili , Liang Fan , Liu Sanyang , Zhang Wenxin , Sun Shuai , Sun Yuhui , Fan Fei , Wang Linying , Liang Xinming , Qiu Weijin , Fan Guangyi , Wang Ou , Yang Weifei , Zhang Jiezhong , Xiao Yuhui , Wang Yang , Wang Depeng , Qu Shoufang , Chen Fang , Huang Jie 
Published: March 2021

Abstract
The importance of structural variants (SVs) for human phenotypes and diseases is now recognized. Although a variety of SV detection platforms and strategies that vary in sensitivity and specificity have been developed, few benchmarking procedures are available to confidently assess their performances in biological and clinical research. To facilitate the validation and application of these SV detection approaches, we established an Asian reference material by characterizing the genome of an Epstein-Barr virus (EBV)-immortalized B lymphocyte line along with identified benchmark regions and high-confidence SV calls. We established a high-confidence SV callset with 8938 SVs by integrating four alignment-based SV callers, including 109× Pacific Biosciences (PacBio) continuous long reads (CLRs), 22× PacBio circular consensus sequencing (CCS) reads, 104× Oxford Nanopore Technologies (ONT) long reads, and 114× Bionano optical mapping platform, and one de novo assembly-based SV caller using CCS reads. A total of 544 randomly selected SVs were validated by PCR amplification and Sanger sequencing, demonstrating the robustness of our SV calls. Combining trio-binning-based haplotype assemblies, we established an SV benchmark for identifying false negatives and false positives by constructing the continuous high-confidence regions (CHCRs), which covered 1.46 gigabase pairs (Gb) and 6882 SVs supported by at least one diploid haplotype assembly. Establishing high-confidence SV calls for a benchmark sample that has been characterized by multiple technologies provides a valuable resource for investigating SVs in human biology, disease, and clinical research.
Concordance of antibiotic prescribing with the American Dental Association acute oral infection guidelines within Veterans’ Affairs (VA) dentistry
Authors: Carlsen Daniel B. , Durkin Michael J. , Gibson Gretchen , Jurasic M. Marianne , Patel Ursula , Poggensee Linda , Fitzpatrick Margaret A. , Echevarria Kelly , McGregor Jessina , Evans Charlesnika T. , Suda Katie J. 
Published: March 2021

AbstractObjective:United States dentists prescribe 10% of all outpatient antibiotics. Assessing appropriateness of antibiotic prescribing has been challenging due to a lack of guidelines for oral infections. In 2019, the American Dental Association (ADA) published clinical practice guidelines (CPG) on the management of acute oral infections. Our objective was to describe baseline national antibiotic prescribing for acute oral infections prior to the release of the ADA CPG and to identify patient-level variables associated with an antibiotic prescription.Design:Cross-sectional analysis.Methods:We performed an analysis of national VA data from January 1, 2017, to December 31, 2017. We identified cases of acute oral infections usingInternational Classification of Disease, Tenth Revision, Clinical Modification(ICD-10-CM) codes. Antibiotics prescribed by a dentist within ±7 days of a visit were included. Multivariable logistic regression identified patient-level variables associated with an antibiotic prescription.Results:Of the 470,039 VA dental visits with oral infections coded, 12% of patient visits with irreversible pulpitis, 17% with apical periodontitis, and 28% with acute apical abscess received antibiotics. Although the median days’ supply was 7, prolonged use of antibiotics was frequent (≥8 days, 42%–49%). Patients with high-risk cardiac conditions, prosthetic joints, and endodontic, implant, and oral and maxillofacial surgery dental procedures were more likely to receive antibiotics.Conclusions:Most treatments of irreversible pulpitis and apical periodontitis cases were concordant with new ADA guidelines. However, in cases where antibiotics were prescribed, prolonged antibiotic courses >7 days were frequent. These findings demonstrate opportunities for the new ADA guidelines to standardize and improve dental prescribing practices.