bluuebunny/crossref_metadata_2025_split huggingface dataset:
Can alcohol consumption in Germany be reduced by alcohol screening, brief intervention and referral to treatment in primary health care? Results of a simulation study
Authors: Manthey Jakob , Solovei Adriana , Anderson Peter , Carr Sinclair , Rehm Jürgen 
Published: August 2021

BackgroundScreening, brief intervention and referral to treatment (SBIRT) is a programme to reduce alcohol consumption for drinkers with high alcohol consumption levels. Only 2.9% of patients in primary health care (PHC) are screened for their alcohol use in Germany, despite high levels of alcohol consumption and attributable harm. We developed an open-access simulation model to estimate the impact of higher SBIRT delivery rates in German PHC settings on population-level alcohol consumption.Methods and findingsA hypothetical population of drinkers and non-drinkers was simulated by sex, age, and educational status for the year 2009 based on survey and sales data. Risky drinking persons receiving BI or RT were sampled from this population based on screening coverage and other parameters. Running the simulation model for a ten-year period, drinking levels and heavy episodic drinking (HED) status were changed based on effect sizes from meta-analyses.In the baseline scenario of 2.9% screening coverage, 2.4% of the adult German population received a subsequent intervention between 2009 and 2018. If every second PHC patient would have been screened for alcohol use, 21% of adult residents in Germany would have received BI or RT by the end of the ten-year simulation period. In this scenario, population-level alcohol consumption would be 11% lower than it was in 2018, without any impact on HED prevalence. Screening coverage rates below 10% were not found to have a measurable effect on drinking levels.ConclusionsLarge-scale implementation of SBIRT in PHC settings can yield substantial reductions of alcohol consumption in Germany. As high screening coverage rates may only be achievable in the long run, other effective alcohol policies are required to achieve short-term reduction of alcohol use and attributable harm in Germany. There is large potential to apply this open-access simulation model to other settings and for other alcohol interventions.
Reduced-port laparoscopic distal gastrectomy in obese gastric cancer patients
Authors: Kang Dong Yeon , Kim Ho Goon , Kim Dong Yi 
Published: August 2021

Background
Reduced-port laparoscopic gastrectomy is currently widely performed for patients with gastric cancer. However, its safety in obese patients has not yet been verified. This is the first study on reduced-port laparoscopic distal gastrectomy (RpLDG) in obese patients with gastric cancer. This study aimed to evaluate the short-term surgical outcomes and investigate the feasibility and safety of RpLDG in obese patients with gastric carcinoma.

Material and methods
A total of 271 gastric cancer patients who underwent RpLDG at our institution were divided into two groups: non-obese [body mass index (BMI) <30 kg/m2, n = 251; NOG] and obese (BMI ≥30 kg/m2, n = 20; OG). The mean age of the enrolled patients was 64.8 ± 11.4 years, with 72.0% being men and 28.0% women. Operative details and short-term surgical outcomes, including hospital course and postoperative complications, were compared by retrospectively reviewing the medical records.

Results
No significant difference in operation time was found between the NOG and OG (205.9 ± 40.0 vs. 211.3 ± 37.3 minutes, P = 0.563). Other operative outcomes in the OG, including estimated blood loss (54.1 ± 86.1 vs. 54.0 ± 39.0 mL, P = 0.995) and retrieved lymph nodes (36.2 ± 16.4 vs. 35.5 ± 18.2, P = 0.875), were not inferior to those in the NOG. There were also no statistical differences in short-term surgical outcomes, including the incidence of surgical complications (13.9% vs. 10.0%, P = 1).

Conclusion
RpLDG can be performed safely in obese gastric cancer patients by an experienced surgeon. It should be considered a feasible alternative to conventional port distal gastrectomy.
Preface
Authors: Kertész Attila 
Published: August 2021

The 12th Conference of PhD Students in Computer Science (CSCS) was organized by the Institute of Informatics of the University of Szeged (SZTE) and held in Szeged, Hungary, between June 24–26, 2020.
The members of the Scientific Committee were the following representatives of the Hungarian doctoral schools in Computer Science: János Csirik (Co-Chair, SZTE), Lajos Rónyai (Co-Chair, SZTAKI, BME), Péter Baranyi (SZE), András Benczúr (ELTE), András Benczúr (SZTAKI), Hassan Charaf (BME), Tibor Csendes (SZTE), László Cser (BCE), Erzsébet Csuhaj-Varjú (ELTE), József Dombi (SZTE), István Fazekas (DE), Zoltán Fülöp (SZTE), Aurél Galántai (OE), Zoltán Gingl (SZTE), Tibor Gyimóthy (SZTE), Katalin Hangos (PE), Zoltán Horváth (ELTE), Márk Jelasity (SZTE), Zoltán Kása (Sapientia EMTE), László Kóczy (SZE), János Levendovszki (BME), Gyöngyvér Márton (Sapientia EMTE), Branko Milosavljevic (UNS), Valerie Novitzka (TUKE), László Nyúl (SZTE), Marius Otesteanu (UPT), Attila Pethő (DE), Vlado Stankovski (UNILJ), Tamás Szirányi (SZTAKI), Péter Szolgay (PPKE), János Sztrik (DE), János Tapolcai (BME), János Végh (ME), and Daniela Zaharie (UVT).
The members of the Organizing Committee were: Attila Kertész, Balázs Bánhelyi, Tamás Gergely, Judit Jász, and Zoltán Kincses.
There were more than 50 participants and 43 talks in several fields of computer science and its applications (11 sessions). The talks were going in sections in Graphs, Machine Learning, Security, Program Analysis, Healthcare, Simulation, Privacy, Computer Graphics I., Bugs, Computer Graphics II., and Distributed systems.
The talks of the students were completed by 2 plenary talks of leading scientists: Tibor Gyimóthy (University of Szeged, Hungary), and Gábor Tardos (Alfréd Rényi Institute of Mathematics, Hungary).
The open-access scientific journal Acta Cybernetica offered PhD students to publish the paper version of their presentations after a careful selection and review process. Altogether 29 manuscripts were submitted for review, out of which 22 were accepted for publication in the present special issue of Acta Cybernetica.
The full program of the conference, the collection of the abstracts and furtherinformation can be found at https://www.inf.u-szeged.hu/~cscs/.
On the basis of our repeated positive experiences, the conference will be organized in the future, too. According to the present plans, the next meeting will be held around the end of June 2022 in Szeged.
A dor nos tempos da Covid-19: Transtorno de adaptação nos professores do ensino superior brasileiro
Authors: Nascimento Eduardo Mendes , Cornaccione Jr Edgard Bruno , Carvalho Marcia Garcia 
Published: August 2021

Neste trabalho são apresentados resultados de uma pesquisa longitudinal orientada pelo objetivo de identificar a adaptação dos professores e seus níveis de estresse e ansiedade durante a pandemia da COVID-19. Assim, 129 professores foram acompanhados por um ano durante a pandemia de modo a obter os dados. Foi possível perceber que aproximadamente 3 em cada 4 professores da amostra passaram pelo transtorno de ajustamento durante o período de coleta e 1 em cada 2 professores apresentaram nível de ansiedade-estado alto. Nesse sentido, verificaram-se os seguintes fatores associados à probabilidade de não estarem adaptados à pandemia: ser mulher, estar casado e a forma negativa com que percebem o cotidiano após tantas restrições e riscos. Entretanto, outros fatores puderam contribuir com o ajustamento dos professores: tempo de docência, percepção positiva sobre o estado de saúde física e não utilização de substâncias como álcool, cigarro, medicamentos e outras. Verificou-se, pois, a vulnerabilidade psicossocial dos professores durante o período de pandemia, o que torna inequívoca a necessidade de desenvolvimento de políticas públicas e privadas para contribuir com o ajustamento dessas pessoas, principalmente pensando na repercussão negativa que essa situação pode ter, inclusive, ao longo de anos.
Study of clinical outcome of patients undergoing intestinal anastomoses with single layer extramucosal technique and double layer anastomoses
Authors: Rai Arvind , J. Sukantth R. 
Published: August 2021

Background: Intestinal anastomosis is one of the common surgeries for cases like bowel obstruction, incarcerated hernias, benign and malignant tumours of small and large bowel. The ideal intestinal anastomosis does not leak and allow normal function of the gastrointestinal tract. This study compared single layer versus double layer intestinal anastomosis in terms of duration, postoperative complications like anastomotic leak.Methods: A total of 100 patients admitted in Hamidia hospital, based on history and clinical examinations and radiological examinations, placed in two groups, group A (single layer anastomosis) and group B (double layer anastomosis) and were operated by a qualified surgical specialist. Data analysis of anastomotic time, anastomotic leak was done and statistical tests of significance were applied. A p value less than 0.05 is considered as significant.Results: In group A (single layer) the time required to perform in 30 (60%) patients is between 16-20 minutes. In double layer, maximum were done in between 26 to 30 minutes, 32 (64%). In our study of 100 patients, there were 6 anastomotic leaks, of which four of them were in group A (single layer) and 2 of them in group B (double layer).Conclusions: In our study, the duration required to perform a single layer intestinal anastomosis is significantly lesser when compared to double layer. There is no significant difference in anastomotic leak between two groups. Less time with no difference in complications, a move towards single layer anastomosis should be preferred.
Effect of aqueous Extract of Terminalia bellirica fruit pulp on Alcohol affected learning in swiss albino mice
Authors: Sowmya  , VR Manohar , Rai Mohandas , Gopalakrishna H N , R Chandrashekar 
Published: August 2021

To evaluate the effect of Aqueous extract of Terminalia belliricafruit pulp (AETB) on learning by Hebb William maze model in mice with acute alcohol consumption.Swiss albino mice (n=48) of either sex weighing 20-30g will be divided into eight groups of six mice each. Drugs were given orally after 12 hours of fasting. Group I mice received 10ml/kg of Normal Saline, Group II mice received Piracetam 200mg/kg, Group III received AETB 36mg/kg, Group IV received ethanol 1.5g/kg orally, Group V received ethanol(1.5g/kg )+ piracetam (200mg/kg), Group VI mice received ethanol(1.5g/kg) +AETB(9mg/kg), Group VII mice received ethanol(1.5g/kg) +AETB (18mg/kg), Group VIII mice received ethanol(1.5g/kg) +AETB(36mg/kg). Time taken by the animal to reach the reward chamber from the start chamber (TRC) in Hebb-William maze was used as a parameterto evaluate the learning.Acute alcohol administration showed increase in TRC. Whereas, acute administration of Aqueous extracts of Terminalia belliricafruit pulp showed a decrease in TRC when compared to the control group. The TRC values for the groups that were administered AETB along with acute alcohol administration showed decrease in TRC values compared to the negative control.Current study showed acute alcohol administration caused impairment of thelearning ability in mice. Whereas, acute administration of Aqueous extracts of Terminalia belliricafruit pulp (AETB)caused enhancement of learning. Pre-treatment with AETB before acute alcohol administration indicated protective action of AETB on alcohol affected learning in mice.
Kemampuan Komunikasi Matematis Siswa dalam Menyelesaikan Masalah Matematika ditinjau dari Perbedaan Kecerdasan Intrapersonal
Authors: Fiqih Riezka Nur , Fitriyani Harina 
Published: August 2021

Kemampuan komunikasi matematis memiliki peran yang sangat penting dalam pembelajaran matematika karena siswa harus mampu mengkomunikasikan ide matematikanya secara tulisan maupun lisan. Sedangkan untuk memahami potensi diri diperlukan kecerdasan intrapersonal yang memadai. Oleh karenanya tujuan penelitian ini adalah untuk mendeskripsikan kemampuan komunikasi matematis siswa dalam menyelesaikan masalah matematika yang ditinjau dari tingkat kecerdasan intrapersonal siswa. Penelitian ini menggunakan pendekatan kualitatif dengan melibatkan 3 orang siswa kelas VII di salah satu SMP Negeri di Kota Pangkalpinang yang masing-masing memiliki kecerdasan intrapersonal tinggi, sedang dan rendah. Pengambilan data penelitian menggunakan angket kecerdasan intrapersonal, tes materi bangun datar yang terdiri dari 3 butir soal essay dan pedoman wawancara. Adapun analisis data menggunakan model Miles dan Huberman yakni reduksi data, penyajian data dan kesimpulan. Hasil penelitian menunjukkan bahwa kemampuan matematis yang paling baik ditunjukkan oleh subjek berkecerdasan intrapersonal sedang, disusul dengan subjek berkecerdasan intrapersonal rendah dan tinggi. Temuan penelitian ini menunjukkan bahwa tingginya level kecerdasan intrapersonal tidak lantas berbanding lurus dengan kemampuan komunikasi matematis siswa.
Kata kunci: Komunikasi Matematis, Kecerdasan Intrapersonal, Masalah Matematika
Eksplorasi Etnomatematika pada Candi Agung Gumuk Kancil Banyuwangi sebagai Lembar Kerja Siswa
Authors: Krismonita Marenda Dias , Sunardi Sunardi , Yudianto Erfan 
Published: August 2021

Etnomatematika adalah matematika yang ditemukan dalam budaya masyarakat yang tanpa sadar telah menerapkan konsep matematika dalam budayanya. Tujuan dari penelitian kualitatif dengan pendekatan etnografi ini adalah untuk mendeskripsikan etnomatematika pada bangunan Candi Agung Gumuk Kancil. Subjek penelitian ini adalah satu orang penjaga candi, satu orang masyarakat yang paham tentang sejarah pembangunan candi dan satu orang yang terbiasa memugar candi. Metode pengumpulan data yang digunakan adalah observasi, wawancara dan dokumentasi. Hasil penelitian ini menunjukkan adanya etnomatematika pada bangunan Candi Agung Gumuk Kancil. Unsur geometri yang ditemukan meliputi: bangun datar (segitiga, persegi, persegi panjang, dan lingkaran), bangun ruang (kubus, balok, dan tabung), kesebangungan, kekongruenan, dan transformasi geometris (translasi dan refleksi). Etnomatematika pada penelitian ini akan dibuat LKS dengan materi bangun ruang sisi lengkung untuk kelas IX semester genap.
Kata kunci: Etnomatematika, Candi Agung, Geometri
Etnomatematika pada Aktivitas Pembuatan Gerabah di Desa Kesilir Wuluhan Jember sebagai Lembar Kerja Siswa
Authors: Agustin Fauziah Dwi , Sugiarti Titik , Yudianto Erfan , Priciliya Sinta , Dewi Niken Shofiana 
Published: August 2021

Etnomatematika adalah kegiatan yang dilakukan oleh sekelompok budaya dimana tanpa mereka sadari terdapat penerapan atau konsep dasar matematika di dalamnya. Kehadiran matematika yang bernuansa budaya akan memberikan kontribusi yang besar terhadap matematika sekolah. Tujuan adanya etnomatematika adalah untuk mengakui bahwa ada cara-cara berbeda dalam melakukan aktivitas matematika dengan mempertimbangkan pengetahuan matematika yang dikembangkan dalam berbagai sektor masyarakat. Penelitian ini bertujuan untuk mengetahui aktivitas etnomatematika apa saja yang dilakukan oleh pengrajin gerabah di desa Kesilir Wuluhan Jember dan menjadikannya sebagai lembar kerja siswa. Jenis penelitian ini adalah penelitian kualitatif dengan pendekatan etnografi. Metode pengumpulan data yang digunakan yaitu observasi dan wawancara. Hasil dari penelitian ini menunjukkan bahwa ada konsep matematika pada aktivitas pengrajin gerabah meliputi aktivitas menghitung, aktivitas mengukur, dan aktivitas mendesain. Etnomatematika dalam penelitian ini akan dibuat lembar kerja siswa untuk kelas VII SMP
Kata kunci: Etnomatematika, Aktivitas Pembuatan Gerabah, Lembar Kerja Siswa.
Analisis Komunikasi Matematis Siswa Kelas X SMK Muhammadiyah 3 Tegaldlimo dalam Menyelesaikan Soal Matematika
Authors: Dewi Ditia Puspita , Susanto Susanto , Sugiarti Titik , Munir Muhammad Habib 
Published: August 2021

Abstrak. Tujuan penelitian ini adalah mendeskripsikan komunikasi matematis siswa kelas X SMK Muhammadiyah 3 Tegaldlimo dalam menyelesaikan masalah matematika. Jenis penelitian ini adalah penelitian kualitatif dengan subjek penelitian siswa kelas X RPL SMK Muhammadiyah 3 Tegaldlimo. Metode pengumpulan data dalam penelitian ini menggunakan metode tes dan wawancara. Hasil tes menunjukkan bahwa kemampuan komunikasi matematis siswa dalam menulis berada pada kategori sedang. Hasil wawancara menunjukkan bahwa kemampuan komunikasi matematis siswa bervariasi yaitu rendah, sedang, dan tinggi. Siswa dengan kemampuan komunikasi tinggi, 1 dari 4 siswa yang melakukan wawancara telah memenuhi semua indikator kemampuan komunikasi matematis. Siswa dengan kemampuan komunikasi matematis sedang, 2 dari 4 siswa yang melakukan wawancara telah memenuhi indikator menulis simbol matematika dan tanda baca, serta mampu menyajikan pemecahan masalah dalam bentuk grafik, namun terbatas pada indikator menulis gagasan dan masalah dalam pembelajaran bentuk kalimat matematika.
Kata kunci: kemampuan komunikasi matematis, sistem persamaan linier, siswa sekolah menengah kejuruan
Surgery Treatment of an Adult Patient with Camurati-Engelmann Disease
Authors: Saboya Fernando , Medina Adriana , Cadavid Sergio , Fuentes Ruben , Jiménez-Canizales Carlos Eduardo 
Published: August 2021

Case:
A 40-year-old Colombian woman presented with a 7-year history of progressive lower-limb pain. Sclerosis of the diaphyseal tibia and femur was observed in her latest x-ray images. A narrowing of the medullary canal is observed in Camurati-Engelmann disease (CED), a rare and progressive diaphyseal dysplasia that was confirmed in this patient by genetic testing. Medical treatment was unsuccessful; thus, surgical treatment consisted of decompression by drilling of the medullary canal was performed, achieving successful pain release.

Conclusion:
Surgical treatment should be considered for patients with CED when the medical treatment is unsuccessful because doing so reduces bone overgrowth, leading to pain relief.
Long-lasting memory of jasmonic acid-dependent immunity requires DNA demethylation and ARGONAUTE1
Authors: Wilkinson Samuel , Muench Amos , Wilson Robert , Hooshmand Kourosh , Henderson Michael , Moffat Emma , Stassen Joost , Sánchez Ana López , Fomsgaard Inge , Krokene Paal , Magerøy Melissa , Ton Jurriaan 
Published: August 2021

Abstract
Stress can alter important plant life-history traits. Here, we report the long-term effects of the stress hormone jasmonic acid (JA) on the defence phenotype, transcriptome and DNA-methylome of Arabidopsis. Three weeks after transient JA signalling activity, 5-week-old plants retained induced resistance (IR) against herbivory but showed enhanced susceptibility to necrotrophic and biotrophic pathogens. Transcriptome analysis of these plants revealed priming and/or up-regulation of JA-dependent defence genes but repression of ethylene- and salicylic acid-dependent genes. Long-term JA-IR against herbivory was associated with shifts in glucosinolate composition and required MYC2/3/4 transcription factors, DNA (de)methylation pathways and the small RNA (sRNA)-binding protein ARGONOUTE1 (AGO1). Although methylome analysis did not reveal consistent changes in DNA methylation near MYC2/3/4-controlled genes, JA-treated plants were specifically enriched with hypomethylated ATREP2 transposable elements (TEs), while ATREP2-derived sRNAs showed increased association with AGO1. Our results indicate that AGO1-associated sRNAs from hypomethylated ATREP2 TEs trans-regulate long-lasting memory of JA-dependent immunity.
Finite-time Tracking Control with Velocity Constraints for the Stochastic Rehabilitative Training Walker System Considering Different Rehabilitee Masses
Authors: Sun Ping , Wang Shuoyu , Shan Rui 
Published: August 2021

Abstract
This study discusses a finite-time tracking controller for a rehabilitative training walker that imposes velocity constraints. The walker was described using a stochastic model through which the rehabilitee mass can randomly change, and a velocity constraint method was proposed to control the velocity input to every omniwheel based on a model predictive algorithm. This approach is novel in that the velocity constraint information obtained from the kinematics model was used to design the tracking controller based on the stochastic dynamic model, thus successfully constraining the actual velocity of walker as per the stochastic system. The nonlinear tracking controller was built for the stochastic rehabilitative walker to make the system’s finite time stable. Also, simulation and experiment were performed, and results confirmed that the proposed tracking control method with velocity constraints is very effective, so it may enable various rehabilitees to train safely.
Potential ligand-receptor-pathway cascades and a novel non-metabolic function of lactate in remodeling uterine receptivity by inducing endometrial histone lactylation at implantation, revealed by a proteomic atlas of maternal-fetal crosstalk
Authors: Yang Qianying , Liu Juan , Wang Yue , Zhao Wei , Wang Wenjing , Cui Jian , Yang Jiajun , Yue Yuan , Zhang Shuai , Chu Meiqiang , Lyu Qingji , Ma Lizhu , Tang Yawen , Hu Yupei , Miao Kai , Zhao Haichao , Tian Jianhui , An Lei 
Published: August 2021

Abstract
Well-orchestrated maternal-fetal crosstalk involves secreted ligands, interacting receptors, and coupled pathways between the conceptus and endometrium. However, previous researches mainly focused on either the conceptus or endometrium in isolation. The lack of integrated analysis, especially on protein levels, has made it challenging to advance our understanding of the crosstalk. Herein, focusing on ligand–receptor complexes and coupled pathways at maternal-fetal interface in sheep, a well-established embryo implantation model, we provide the first comprehensive proteomic atlas of ligand-receptor-pathway cascades that may be essential for implantation. Based on these candidate interactions, we further revealed the physical interaction of albumin-claudin 4 and their role in facilitating embryo attachment to endometrium. More interestingly, we demonstrated a novel non-metabolic function of enhanced conceptus glycolysis in remodeling uterine receptivity, by inducing endometrial histone lactylation, a newly identified histone modification. Our results from in vitro and in vivo models supported the essential role of lactate, as a key embryonic signal, in regulating redox homeostasis and apoptotic balance to ensure successful implantation. Our study identified many putative molecular and cellular mechanisms that fine-tuned conceptus-endometrium crosstalk during implantation, thus providing important clues for developing potential clinical intervention strategies to improve pregnancy outcomes following both natural conception and assisted reproduction.
Effect of pile driving on ground vibration in clay soil: Numerical and experimental study
Authors: Noori Hirad Shamimi , Shirinabadi Reza , Moosavi Ehsan 
Published: August 2021

Abstract
In this study, peak particle velocity (PPV) values for driving three piles with 40 cm, 50 cm, and 70 cm in a clayey soil through the impact piling method are investigated by an experimental study and a numerical simulation. An experimental study is carried out on a scale of 1:20 of the operation. Numerical simulation is performed by using an axisymmetric model in PLAXIS 2D finite element software. Properties of the soil and the piles used in the experimental study are obtained from geotechnical tests and employed in the numerical simulation. The model has been verified by comparing the acquired PPV values with those measured in the experimental study. The results show a good agreement between the computed values and the field data. Moreover, measured peak particle velocities in the experimental study indicate that an increase in the diameter of the pile can increase the level of ground vibration. Some sensitivity analyses have been performed by numerical modeling to determine the effect of soil and pile properties on the changes of PPV. The results indicate that increase in friction angle of the soil and pile diameter and reduction in elastic modulus of soil will increase the level of ground vibration.