bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mineralization of Melanoidin by H₂O₂ Producing Enzymes from Marine Cyanobacteria Oscillatoria boryana BDU 92181
Authors: Kalavathi D. Francisca 
Published: May 2021

Intracellular enzymes of Oscillatoria boryana BDU 92181 exhibited mineralizing activity on melanoidin, a recalcitrant pigment present in the distillery wastewater. Melanoidin decolourization was postulated to be due to the production of hydrogen peroxide and molecular oxygen released by the cyanobacterium during photosynthesis. The present study was aimed to find out the efficacy of the marine cyanobacterium O. boryana BDU 92181 in producing H2O2 and enzymes involved in hydrogen peroxide production with a view to utilize its potential for decolorization of melanoidin pigment in the distillery effluent. The enzymes involved in the melanoidin degradation have not so far been attempted with cyanobacteria.
The results obtained in the present work suggested the activity of the glucose oxidase and Manganese peroxidase enzymes in a marine cyanobacterium Oscillatoria boryana BDU 92181 and whose activity was found to be enhanced in the presence of melanoidin.
Sickle Cell Disease: An Overview of Oral Health Considerations for Pediatric Patients
Authors: Eleftherou Dafni , Arhakis Aristidis , Davidopoulou Sotiria 
Published: May 2021

Aim: This literature review aims to update the evidence for orofacial manifestations and current treatment recommendations for children and adolescents with sickle cell disease.
Background: Sickle cell disease is a frequent hemoglobinopathy and a life-threatening genetic disorder. The lifelong condition is characterized by chronic hemolytic anemia and vaso-occlusive crisis that may occur in a variable range of clinical presentations in different regions of the body, including the oral cavity.
Review results: This review explored the most common orofacial alterations of pediatric patients with SCD. Dental caries is a common finding in SCD pediatric patients, especially in those who are socio-economically vulnerable. Moreover, malocclusions occur in high prevalence in SCD pediatric patients. Other oral health complications seen in SCD patients include periodontal inflammation, bone changes, infections, mental nerve neuropathy, facial overgrowth, delayed tooth eruption, dental anomalies, pulp necrosis, soft tissue alterations and salivary changes. Dental infections may trigger a vaso-occlusive crisis leading the patient to a higher probability on arriving in hospital emergency departments and in need for further hospital admission to deal with the correlated complications. Thus, preventive dental care and non-invasive dental procedures are the principal focus in SCD patients in order to avoid possible subsequent complications.
Conclusion: The review showed that in pediatric patients with SCD the risk for orofacial manifestations and complications depends not only on the presence of SCD but also on other confounding factors such as oral hygiene, diet habits and social conditions. Moreover, more well-designed epidemiological studies are necessary to assess the real link between SCD disease and its impact on stomatognathic health.
Periodontal Disease Status in a Population at Najran Province of Saudi Arabia
Authors: Alshabab Ahmed Zafer , Almakrami Monsour Heba , Almilaq Faisal Hassan , Alhareth Ibrahim Saleh , Hossain Md. Zahid , Hyderah Khaled Mashoor , Aseri Abdulrahman Ahmed , Alanazi Sultan Mohammed , Abdulrazzaq Mohammad Abdo 
Published: May 2021

Background: The common periodontal diseases are of public health concern, with 20-50 percent of the global population affected by gingivitis and or periodontitis.
Aim: The aim of this study was to explore the common periodontal diseases occurring among the patients who attended the College of Dentistry hospital of Najran University. And also, to determine the correlation among the age groups, nationalities and risk factors related to periodontal diseases.
Methods: A retrospective hospital-based descriptive type study was performed, providing 352 records of male patients suffering from various types of periodontal diseases. The Centers for Disease Control and the American Academy of Periodontology (CDC-AAP) classification was used for periodontal diagnosis. Patients were grouped by age as group A (6-20 years), group B (21-40 years), group C (41-60 years) and group D (above 60 years). Chi-square test and multinomial logistic regression model were adapted for data analyses.
Results: Out of 352 patients, 217 (61%) and 135 (39%) patients suffered from gingivitis and periodontitis, respectively. Mean age of the patients was 32.81 ± 15.96 (range 6-97) years. Sixty-nine (19.6%), 200 (56.8%), 60 (17.0%) and 23 (6.5%) patients of Group A, B, C and D suffered from different forms of periodontal diseases, respectively. Eighty three percent patients were of Saudis and Yemenis and the rest were of Egyptian, Bangladeshi, Pakistani, Indian, Sudanese, Jordanian, Syrian, Chadian, Ghanaian and Tunisian nationalities. Highest number of patients suffered from moderate generalized gingivitis 142 (40.3%) and moderate localized periodontitis 57 (16.2%). Majority had plaque & calculus 290 (82.4%) and the rests had diabetes mellitus, smoking and tobacco chewing habit, asthma, hypertension and heart disease. Correlations among periodontal disease, age group and risk factor were found significant (p <0.05) though between the nationality and risk factor was found not significant (p 0.999).
Conclusions: Significant relationships were observed among periodontal diseases and age, nationality and risk factors. This small study of Najran may reflect the periodontal status in a population of Saudi Arabia. Further broad scale study would be conclusive establishing such relationship in Saudi Arabian population.
Repair Responses of Pulp Tissues after Different Direct Pulp Capping Materials at Different Storage Time
Authors: Dogheim Ali Yakout , Noaman Khaled Mohamed , Kawana Khadiga Youssef , Al Samolly Walaa Mohamed 
Published: May 2021

Objective: The objective of this study was to evaluate and compare histologically the repair response following direct pulp capping of mechanically exposed dogs' teeth with: Dycal, UltraBlend Plus and TheraCal LC: at different time intervals (1 week, 1 month and 3 months)
Materials and methods: A total of 54 permanent teeth of six healthy male mongrel dogs were used, divided into three groups (n=18) according to pulp capping material used. Group I: Dycal, Group II: UltraBlend Plus and Group III: TheraCal LC. All cavities were restored with Riva LC Resine Modified Glass Ionomer. Each group was subdivided into three subgroups according to storage time (n=6). Control samples (3 teeth) were added representing normal untouched teeth. The specimens were fixed, decalcified, processed to paraffin blocks. Serial sections of 5 microns thickness were prepared and stained with H&E then examined under light microscope for histologic examination and were evaluated histologically for pulp tissue organization and reparative tissue formation following scoring system used by Nowicka et al.
Results: As regards calcific barrier, all three materials, by the end of third month showed: continuity (score 3) with irregular dentin bridge formation, the morphology showed mostly irregular hard tissue and the tubules were mild in most specimens.
Conclusion: Theracal is superior to Dycal and UBP for pulp capping of mechanically exposed human teeth, it can be used as an effective direct pulp capping material. There was no statistically significant difference between the three capping agents by end of third evaluation period as regards calcific barrier and odontoblastic layer.
Edible Fungi Consumed by the Lamba and Bemba People of Haut-Katanga (DR Congo)
Authors: Wa Ngoy Kashiki Bill Kasongo , De Kesel André , Kabange Mukala Ernest , Bostoen Koen , Degreef Jérôme 
Published: May 2021

The objective of this work is to establish a list of species of edible fungi consumed by the Lamba and Bemba people of Haut-Katanga (DR Congo). This study contributes to the valorization of edible fungi gathered in the miombo woodlands of Haut-Katanga. A survey was conducted among Lamba and Bemba people of the peri-urban area of Lubumbashi. The first author conducted structured and semi-structured surveys among 331 people, mostly women aged 30-50.
The results show the existence of thirty-eight edible species belonging to 9 genera and 8 families. The majority is ectomycorrhizal (66%) followed by Termitomyces (21%), while only a few are saprotrophic (13%). Lamba and Bemba people consume all taxa. Twenty-three local names have been recorded in their respective languages, i.e., Kilamba and Kibemba, two closely related Bantu languages belonging to the family’s Eastern clade. The Lamba and Bemba do not consume species of the genera Russula (Russulaceae) and Boletus (Boletaceae). We succeeded in reconstructing the conceptualization underlying the creation of several Kibemba and Kilamba mushroom names. Popular and scientific taxonomies rarely overlap: one and the same species may have different names in Kilamba and Kibemba, while one and the same name in Kilamba and/or Kibemba is often used for several congeneric species. Species considered toxic and not consumed do not have a Kilamba or Kibemba name of their own. Instead, they are collectively referred to by a term fyana fya bene, literally meaning “big (dangerous) children of them” and signaling that local consumers reject those species.
Socio-technical Context of Market Gardening in the Ruzizi Plain in Eastern DRC: Constraints and Stakeholders' Strategies
Authors: Rushigira Cadeau , Mirindi Germaine Furaha , Ngezirabona Stany Vwima 
Published: May 2021

The Ruzizi Plain in general and the community of Ruzizi Plain in particular, although having considerable potential for the development of market gardening, do not manage to satisfy the demand for market garden produce in the main consumption area (Bukavu town), which continues largely to depend on Rwanda in its supplies. This situation suggests that market gardening in Ruzizi Plain is conducted in an environment marked by constraints. Some constraints relate to the actual process of production and marketing, and others are related to the quality requirements imposed by demand.
However, all these constraints are all triggers for the malfunction of market gardening sector. Faced with this, market gardeners adopt adaptive behavior to reduce and turn round these constraints. The choice of strategies by market gardeners depends on the perception of the constraints encountered and the resources available. Done on a sample of 81 market gardeners, this study enables to identify, based on an analysis of the technical context, the constraints of tomato and aubergine at Ruzizi Plain, and the strategies developed by market gardeners in the face of these constraints.
Ambient Air Pollutions along a Major South-Western Nigerian Road
Authors: Adeniyi Gbadebo Omoniyi , Lawal Olusegun Ismail , Egwenu Samuel Okemute , Sonibare Jacob Ademola , Akeredolu Funso Alaba 
Published: May 2021

This study investigated the air pollutants in the ambient air of a typical intercity highway in Nigeria. This was to assess the effect of vehicular emission on air quality along the highway. The results showed that NOX concentrations ranged from 9.9±3.2 to 33.8±3.3 µg/m3 during the wet season and 19.0±1.2 to 35.4±2.3 µg/m3 during the dry season. Sulfur dioxide measured along this highway ranged from 49.7±38.1 to 219±18.1 µg/m3 during the wet season while dry season concentration ranged from 89.1±20.9 to 225.4±57.9 µg/m3. The TSP during the wet season ranged from 54.4±25.6 to 126.8±25.6 µg/m3. These values were below the limits of 250 mg/m3 set by FMEnv., and 150-230 mg/m3 by WHO. However, the TSP measured during the dry season ranged from 85.9±44.6 to 277.8±213.5 µg/m3. The average correlations between NOX, SO2, and TSP measured during wet and dry seasons and the traffic density were 0.7, 0.6 and 0.7, respectively. Air pollution along the Nigerian highway is highly linked to vehicular activities.
Bicortical Screw and Needle Welded Together as Effective Implant Technique for Immediate Load of SINGLE Tooth in Aesthetic Zone Characterized by Severe Bony Reabsorption: Cases Report
Authors: Dal Carlo Luca , Pasqualini Marco E. , Rossi Franco 
Published: May 2021

After a long period of time in which submerged implants were used just with delayed load, scientific evidence has led to immediate loading, finally re-evaluating the long lasting experience gotten with one-piece implants.
In aesthetic area, if bone is deep and wide, immediate load can be performed with any type of implants, with scarce risk of failure.
Situations in which bone is scarce are frequent and impose to choose between performing a suitable technique compatible with immediate loading or renouncing to immediate loading.
In our experience, implant technique based on the welding-in-mouth of a titanium needle to main implant is regularly destined to success, because the needle implant, deeply anchored to bone, compensates the lateral forces that normally push the tooth forward.
The long lasting experience accrued since over 30 years in our professional offices leads us to suggest this technique as a standard solution while dealing with bone reabsorption in the aesthetic area. We are certain that further studies will confirm our conclusions.
Validation of the Insomnia Severity Index on Patients Recovering from High Impact Car Accidents
Authors: Cernovsky Zack Z. , Litman Larry C. , Nosonova Vitalina 
Published: May 2021

Background: The Insomnia Severity Index (ISI) is widely used in clinical assessments of insomnia in patients injured in high impact motor vehicle accidents (MVAs). This study examines the criterion and convergent validity of ISI on this clinical population.
Method: De-identified archival data were available on 112 post-MVA patients (37 men, 75 women, mean age 38.8 years, SD=13.1). They completed the ISI as well as the Brief Pain Inventory, the Rivermead Post-concussion Symptoms Questionnaire, the Subjective Neuropsychological Symptoms Scale (SNPSS), Items 10 to 12 of the Whiplash Disability Questionnaire (ratings of depression, anger, and of anxiety), Whetstone Vehicle Anxiety Questionnaire, Driving Anxiety Questionnaire (DAQ), Steiner’s Automobile Anxiety Inventory, and some of them also completed the PTSD Checklist for DSM-5 (PCL-5).
The ISI responses were also available from a community sample of 21 controls (10 men, 11 women, mean age of 39.2 years, SD=18.5).
Results: The mean ISI total score of post-MVA patients (23.6, SD=13.1) was significantly higher than the one of the controls (6.0, SD=5.4) and significant between groups differences in the same direction were also observed on all 7 individual ISI items: the magnitude of these underlying relationships ranged from Pearson point biserial r of 0.68 to 87. The ISI total score also significantly correlated with ratings of post-MVA pain, depression, generalized anxiety, scores on measures of the post-concussion and whiplash syndrome, PTSD, and on Whetstone’s and DAQ measures of post-MVA driving anxiety.
Discussion and Conclusions: The results show an excellent level of criterion and convergent validity of ISI for clinical assessments of insomnia in post-MVA patients.
Evaluation of Salivary Superoxide Dismutase Levels in Oral Submucous Fibrosis – A Cross Sectional Study
Authors: Nagar Kavita , Sujatha G.P. , Lingappa Ashok 
Published: May 2021

Background: Oral Submucous Fibrosis (OSMF) is a potentially malignant disorder with areca nut being the main etiological agent. Increased risk of malignant potential of OSMF necessitates the early diagnosis of the condition. Superoxide dismutase (SOD) scavenges oxygenated free radicals and can be used as a potential biomarker for oral cancer detection.
Objectives: The present study was conducted to estimate and compare salivary SOD levels in patients with OSMF and healthy controls and to compare its levels in different clinical and functional stages of OSMF.
Methodology: The study group (Group 1) included 30 patients of OSMF, and the control group (Group 2) was formed by age and sex-matched healthy individuals. Salivary SOD levels were determined by Nitro Blue Tetrazolium (NBT) chloride method. The levels of salivary SOD were compared between the two groups and the data thus obtained was subjected to statistical analysis using independent sample t-test and one way Analysis of variance (ANOVA) test.
Results: The mean salivary SOD in the study group was 0.583 IU/mL and 0.864 IU/mL in control group and the difference was found to be statistically significant. Thus, the patients with OSMF had significantly lower levels of salivary SOD compared to the controls.
Conclusion: The decrease in the salivary SOD levels in patients with OSMF suggests the role of oxidative stress in the pathogenesis of OSMF and initiation and progression of carcinogenesis. Thus, it can be used as a prognostic marker for early detection of carcinoma in patients with OSMF and thereby, improving the quality of life patients.
Gender Analysis of Sexual Misconduct in UN Peacekeeping Operations
Authors: Naramanik Wirantoputri Rikianarsyi Arrassyidinta 
Published: May 2021

Penelitian ini bertujuan untuk mengeksplorasi faktor penyebab tetap terjadinya eksploitasi dan pelecehan seksual yang dilakukan oleh pasukan perdamaian PBB terhadap perempuan lokal di negara konflik. Penelitian ini menggunakan analisis gender, pendekatan kualitatif dan studi literatur. Hal yang dikaji dalam penelitian ini yakni kebijakan PBB mengenai pelarangan beragam jenis relasi seksual pasukan perdamaian PBB dan perempuan lokal, data laporan tuduhan eksploitasi dan pelecehan seksual yang disampaikan penduduk, dan Indeks Perempuan, Perdamaian, dan Keamanan (WPS Index) dari negara pengirim dan penerima pasukan perdamaian PBB. Penelitian ini berargumen bahwa dalam penugasan misi perdamaian, terdapat aspek gender yang diabaikan oleh PBB, yakni budaya patriarki di kedua kelompok negara, pandangan hyper-masculinism para pasukan militer, dan tujuan berdimensi gender dari negara pengirim yang ingin membentuk dan mempertontonkan identitas mereka sebagai pelindung. Penelitian ini menyarankan kepada PBB agar mengkaji WPS Index negara pengirim sebelum menerima pasukan perdamainnya.

Kata Kunci: Analisis Gender, Eksploitasi dan Pelecehan Seksual, Pasukan Perdamaaian PBB, WPS Index
COVID-19 immunity and vaccines: what a pharmacist needs to know
Authors: Darwish Rula M. 
Published: May 2021

Abstract
COVID-19 vaccines are being produced using different platforms by different companies, some of which are entering Phase 3 and 4 trials. Due to the pandemic, this production has been accelerated, which leaves a window for speculation on the method of production and safety. Pharmacists are familiar with vaccination; however, COVID-19 vaccines are still new and further work is needed to clarify many aspects, including side effects, methods of storage, and number of doses. Prioritization of vaccination has been implemented to a certain extent, but no clear strategy is available. A comprehensive overview on immunity and immunological principles for the design of COVID-19 vaccine strategies is provided in this narrative review and the current COVID-19 vaccine landscape is discussed, in addition to exploring the principles for prioritization of vaccination using data from articles available in PubMed and from health organizations. Pharmacists should have a better understanding of COVID-19 vaccines and their manufacture. This would also allow better counseling of the public on COVID 19, immunization, and explaining prioritization basis and vaccination programs.
Association of industrial work schedules with development of metabolic syndrome, insulin resistance, and serum adipokine concentrations
Authors: Ravibabu Kalahasthi , Jakkam Surender , Ravi Prakash Jamalpur , Adepu Vinay Kumar 
Published: May 2021

Abstract

Background
Association of work schedule in industrial workers with the progression of metabolic syndrome, insulin resistance, and serum adipokine concentrations is incompletely explored.

Objective
To determine the association of work schedule with the progression of metabolic syndrome, insulin resistance, and adipokine concentrations in industrial workers.

Methods
In a cross-sectional study design of industrial workers we compared metabolic syndrome, insulin resistance, and adipokines concentration between workers in the day shift (n = 52), rotational shift (n = 21), and night shift (n = 15). The international Diabetes Federation criteria were used to diagnose metabolic syndrome. We used a homeostatic model assessment of insulin resistance (HOMA-IR). Serum insulin, leptin, and adiponectin concentrations were measured using enzyme-linked immunosorbent assays. Serum glucose, triglyceride, and high-density lipoprotein cholesterol (HDL-C) concentrations were monitored using Prietest clinical chemistry reagents.

Results
The proportional difference in metabolic syndrome (0.31, 95% confidence interval [CI] 0.036–0.587, P = 0.026), median difference of leptin (0.61, 95% CI 0.186–1.034, P = 0.005), and leptin-to-adiponectin ratio (LAR; 0.45, 95% CI 0.235–0.665, P < 0.001) was significantly higher, and serum adiponectin was lower (–2.00, 95% CI −4.197 to 0.197, P = 0.07) in the night-shift workers compared with that of day-shift workers. Among rotational-shift workers, the proportional difference between metabolic syndrome (0.14, 95% CI −0.098 to 0.378, P = 0.25), median difference of leptin (0.25, 95% CI −0.124 to 0.624, P = 0.19), and LAR (0.09, 95% CI −0.099 to 0.279, P = 0.35) was higher, and serum adiponectin concentration was lower (−0.73, 95% CI −2.660 to 1.208, P = 0.46) compared with that of day-shift workers; however, the altered differences were not significant. We observed a higher proportion of difference in HOMA-IR in shift workers (night and rotation) than in day-shift workers.

Conclusion
Night-shift workers are vulnerable to a higher risk of metabolic syndrome, HOMA-IR, and adipokine changes.
Cytogenetic characteristics of and prognosis for acute myeloid leukemia in 107 children
Authors: Chen Wanzi , Yang Jinghui , Chen Ping 
Published: May 2021

Abstract

Background
Patients diagnosed with acute myeloid leukemia (AML) in childhood have a poor prognosis. A better understanding of prognostic factors will assist patients and clinicians in making difficult treatment decisions.

Objectives
To understand further the cytogenetic characteristics of and reassess the prognostic value of cytogenetic abnormalities in childhood AML.

Methods
Conventional karyotypes of 107 children with AML were analyzed retrospectively. The cases were divided into 4 groups based on genetic rearrangements; namely patients with: t(15;17)/PML-RARA; t(8;21)/RUNX1-RUNX1T1 or inv(16)(p13;q22) and t(16;16)/CBFB-MYH11; −7 or complex karyotypes; normal karyotypes or other cytogenetic changes. Differences in age, sex, leukocyte count, event-free survival (EFS), and overall survival (OS) were analyzed.

Results
All French-American-British (FAB) subtypes of AML were detected in 107 patients. We successfully cultured 81 of 107 bone marrow specimens, of which 60 cases had abnormal karyotypes. The most common abnormal karyotypes were t(8;21) (17/81 cases), followed by t(15;17) (13/81 cases), –X/Y (10/81 cases). There were no significant differences (P > 0.05) in age, sex, or leukocyte counts between the 4 groups. The differences in 3-year EFS and OS between each pair were significant, except for groups of patients with t(8;21)/RUNX1-RUNX1T1 and patients with normal karyotypes or other cytogenetic changes (P = 0.054).

Conclusions
Chromosomal abnormalities may provide important prognostic factors for AML in children and be helpful for risk stratification and individual treatment.