bluuebunny/crossref_metadata_2025_split huggingface dataset:
Persisting Motor Function Problems in School-Aged Survivors of Congenital Diaphragmatic Hernia
Authors: de Munck Sophie , van der Cammen-van Zijp Monique H. M. , Zanen-van den Adel Tabitha P. L. , Wijnen René M. H. , Cochius-den Otter Suzan C. M. , van Haren Neeltje E. M. , Gischler Saskia J. , van Rosmalen Joost , IJsselstijn Hanneke 
Published: October 2021

Background and Objectives: Children born with congenital diaphragmatic hernia (CDH) and treated with extracorporeal membrane oxygenation (ECMO), are at risk for motor function impairment during childhood. We hypothesized that all children born with CDH are at risk for persistent motor function impairment, irrespective of ECMO-treatment. We longitudinally assessed these children's motor function.Methods: Children with CDH with and without ECMO-treatment, born 1999–2007, who joined our structural prospective follow-up program were assessed with the Movement Assessment Battery for Children (M-ABC) at 5, 8, 12 years. Z-scores were used in a general linear model for longitudinal analysis.Results: We included 55 children, of whom 25 had been treated with ECMO. Forty-three (78%) were evaluated at three ages. Estimated mean (95% CI) z-scores from the general linear model were −0.67 (−0.96 to −0.39) at 5 years of age, −0.35 (−0.65 to −0.05) at 8 years, and −0.46 (−0.76 to −0.17) at 12 years. The 5- and 8-years scores differed significantly (p = 0.02). Motor development was significantly below the norm in non-ECMO treated patients at five years; −0.44 (−0.83 to −0.05), and at all ages in the ECMO-treated-patients: −0.90 (−1.32 to −0.49), −0.45 (−0.90 to −0.02) and −0.75 (−1.2 to −0.34) at 5, 8, and 12 years, respectively. Length of hospital stay was negatively associated with estimated total z-score M-ABC (p = 0.004 multivariate analysis).Conclusion: School-age children born with CDH are at risk for motor function impairment, which persists in those who received ECMO-treatment. Especially for them long-term follow up is recommended.
lncRNA OR3A4 Promotes the Proliferation and Metastasis of Ovarian Cancer Through KLF6 Pathway
Authors: Guo Fangfang , Du Jianan , Liu Lingling , Gou Yawei , Zhang Mingming , Sun Wei , Yu Hongmei , Fu Xueqi 
Published: October 2021

Aim: Ovarian cancer is a collaborative malignant tumor of the female reproductive system in clinical research. Some clinical studies have shown that OR3A4, which is a cancer-causing lncRNA, plays a major role in promoting the occurrence and development of a variety of tumors. And we also expressed the view that it expressed in ovarian tissue. However, the function of OR3A4 in ovarian cancer remains unclear.Methods and Results: To further verify the function of lncRNA OR3A4 in ovarian cancer, we established the xenograft model in the zebra fish. In this study, cells transformed with OR3A4 shRNA plasmids were transplanted into the zebra fish, and the cell proliferation and migration ability were significantly reduced compared to the empty vector. While knocking out OR3A4, we further downregulated its expression by siRNA of KLF6. Our study found that the knocked out OR3A4 resulted in a decrease in cell proliferation and migration level, which can be found in the downregulated expression of KLF6. We also verify the relationship between OR3A4 and circulating tumor cells in the zebra fish xenograft model, the results indicate that lncRNA OR3A4 may be involved in the resistance of ovarian cancer to complain.Conclusion: lncRNA OR3A4 promotes the proliferation and metastasis of ovarian cancer through the KLF6 pathway.
Nomogram Predicting Parametrial Involvement Based on the Radical Hysterectomy Specimens in the Early-Stage Cervical Cancer
Authors: Li Chunbo , Yang Shimin , Hua Keqin 
Published: October 2021

Objective: Radical hysterectomy (RH) is the surgical standard for the treatment of the early-stage cervical cancer (CC). However, this procedure is associated with a high rate of adverse impact on the quality of the life of the patient. Since the rate of parametrial involvement (PI) is low for the patients with the early-stage CC, some authors believe that the patients with the early-stage CC may benefit from the less radical surgery. This study aims to estimate the incidence of the PI in the patients with the early-stage CC and establish a simple nomogram to identify a cohort of the patients with low risk of the PI who may benefit from the less radical surgery.Methods: All the patients who underwent the RH and pelvic lymphadenectomy were included from 2013 to 2018. The significant independent predictors were identified through the Cox regression analysis and then incorporated into a nomogram to predicate the PI. The calibration plots and receiver operating characteristic (ROC) curves were used to assess the predictive accuracy of the nomogram.Results: A total of 4,533 patients met the inclusion criteria and 441 women (9.7%) had the PI. The positive PI rate in the ≤2 cm group (1.2%) was significantly lower compared to &gt;2– ≤4 cm (6.2%) or &gt;4 cm (22.4%) groups. The multivariate analyses revealed that tumor size (p = 0.002), lymphovascular space invasion (LVSI) (p = 0.001), vaginal involvement (VI) (p &lt; 0.001), status of the pelvic lymph nodes (PLNs) (p = 0.001), and depth of stromal invasion (DSI) (p &lt; 0.001) were the independent prognostic factors of the PI. Finally, the five variables were combined to construct the nomogram model. The concordance indexes (C-indexes) of the PI were 0.756 (95% CI 0.726–0.786) for the internal validation and 0.729 (95% CI 0.678–0.780) for the external validation. The calibration plots further showed good consistency between the nomogram prediction and the actual observation.Conclusion: This study confirmed that the patients with tumor size 2 cm or smaller were at very low risk for the PI. If other variables such as negative LVSI, DSI &lt;50%, no VI, and negative PLN were limited, the risk would reduce significantly. Meanwhile, a simple nomogram based on the significant clinicopathological characteristics could be used as a tool for the clinicians to predict the PI among the patients with the early-stage CC, who might benefit from a less radical surgery.
Investigation of the common Q-switching voltage choice in dual-wavelength alternating Q-switched infrared laser
Authors: Sun Jingdong , Yu Chunhe , Dong Yuan , Yu Yongji , Jin Guangyong 
Published: October 2021

Abstract
A dual-wavelength co-voltage alternating Q-switched infrared laser is demonstrated by combining the voltage-increased and voltage-decreased electro-optic (EO) Q-switched technologies. We experimentally studied the output characteristics of the laser under different common Q-switching voltages. The selection law of the common Q-switching voltage for 1064 nm and 1319 nm dual-wavelength laser is obtained. The results show that the selection of the common Q-switching voltage should be slightly greater than the quarter-wave voltage of 1319 nm laser(1500 V). Otherwise, the threshold of 1319 nm laser will become higher or the difference of maximum single pulse energy between two wavelengths will be greater.
Female genital mutilation (FGM) in Somaliland – why is change so slow?
Authors: Johansson Annika , Osman Gaas Abdirahman , Mahmoud Warsame Amina 
Published: October 2021

Female genital mutilation (FGM) is defined as any procedure involving the alteration or excision of external female genitalia for no medical reason. Somaliland has among the highest prevalence rates of FGM globally. In this article we describe how the Civil Society Organisation (CSO) ‘Network against female genital mutilation in Somaliland’ (NAFIS) has approached the challenge to reduce the high FGM prevalence. From its start in 2006, NAFIS has developed a multifaceted program to reach the overall goal: the elimination of all forms of FGM in Somaliland.
Alone among the group of CSOs in the network, NAFIS introduced in its activities medical care and counselling for women who suffer from the consequences of FGM. From 2011 and onwards, thousands of women have been relieved of their FGM-related health complications and participated in counselling sessions at project centres. Shortly after this visit they have been invited to participate in community group meetings to share their experiences with other women who also have received FGM care and counselling, and other community members.
The aim of the article is to describe this model of work - combining FGM care and counselling with community dialogues. The article is basically descriptive, using the authors’ own observations and encounters with project clients and staff over eight years. We have also used findings from three Master's theses on aspects of the process, and from other small scale studies to highlight people’s understanding, experiences and opinions in a context of an on-going health intervention.
A lesson learnt from NAFIS project is that it has helped to open up communicative spaces in community dialogues where experiences are shared and understanding created of the harm caused by FGM, without the habitual stigma and shame. We discuss this process in a context of behavioural change theories. A major challenge during the process has been to involve men in the project’s FGM information and counselling activities. The role of nurses/midwives, being the first to meet women with FGM complications, is also discussed and the need emphasised to strengthen capacity of this category of health workers. One type of FGM gaining in usage is the poorly defined sunna, the health risks of which are unclear.
ВСЕУКРАЇНСЬКИЙ ТИЖДЕНЬ ДОШКІЛЛЯ В УКРАЇНІ
Authors: Sysoieva Svitlana , Reipolska Olha 
Published: October 2021

Висвітлено результати роботи Всеукраїнського тижня дошкілля, який відбувся 20-24 вересня 2021 р. Вперше за часи незалежної України урочистості з нагоди свята працівників дошкільної освіти тривали впродовж тижня, а події відзначалися широкомасштабністю та різноманітністю. З ініціативи Міністерства освіти і науки України, Національної академії педагогічних наук України, Всеукраїнської громадської організації «Асоціація працівників дошкільної освіти» та за підтримки підкомітету з питань раннього розвитку та дошкільної освіти Комітету Верховної Ради України з питань освіти, науки та інновацій проведено ряд заходів у форматі онлайн і офлайн, щоб якомога більше охочих могли долучитися до них і взяти участь. Серед учасників заходу були провідні вчені, викладачі закладів вищої освіти та інститутів післядипломної освіти, представники дошкільної освіти.
TOI-1518b: A Misaligned Ultra-hot Jupiter with Iron in Its Atmosphere
Authors: Cabot Samuel H. C. , Bello-Arufe Aaron , Mendonça João M. , Tronsgaard René , Wong Ian , Zhou George , Buchhave Lars A. , Fischer Debra A. , Stassun Keivan G. , Antoci Victoria , Baker David , Belinski Alexander A. , Benneke Björn , Bouma Luke G. , Christiansen Jessie L. , Collins Karen A. , Goliguzova Maria V. , Hagey Simone , Jenkins Jon M. , Jensen Eric L. N. , Kidwell Jr Richard C. , Laloum Didier , Massey Bob , McLeod Kim K. , Latham David W. , Morgan Edward H. , Ricker George , Safonov Boris S. , Schlieder Joshua E. , Seager Sara , Shporer Avi , Smith Jeffrey C. , Srdoc Gregor , Strakhov Ivan A. , Torres Guillermo , Twicken Joseph D. , Vanderspek Roland , Vezie Michael , Winn Joshua N. 
Published: October 2021

Abstract
We present the discovery of TOI-1518b—an ultra-hot Jupiter orbiting a bright star (V = 8.95). The transiting planet is confirmed using high-resolution optical transmission spectra from EXPRES. It is inflated, with R

p
= 1.875 ± 0.053 R
J, and exhibits several interesting properties, including a misaligned orbit (

240.34

−
0.98

+
0.93

degrees) and nearly grazing transit (

b
=

0.9036

−
0.0053

+
0.0061

). The planet orbits a fast-rotating F0 host star (T
eff ≃ 7300 K) in 1.9 days and experiences intense irradiation. Notably, the TESS data show a clear secondary eclipse with a depth of 364 ± 28 ppm and a significant phase-curve signal, from which we obtain a relative day–night planetary flux difference of roughly 320 ppm and a 5.2σ detection of ellipsoidal distortion on the host star. Prompted by recent detections of atomic and ionized species in ultra-hot Jupiter atmospheres, we conduct an atmospheric cross-correlation analysis. We detect neutral iron (5.2σ), at

K

p

=

157

−
44

+
68

km s−1 and

V

sys

=
−

16

−
4

+
2

, adding another object to the small sample of highly irradiated gas-giant planets with Fe detections in transmission. Detections so far favor particularly inflated gas giants with radii ≳1.78 R
J, which may be due to observational bias. With an equilibrium temperature of T
eq = 2492 ± 38 K and a measured dayside brightness temperature of 3237 ± 59 K (assuming zero geometric albedo), TOI-1518b is a promising candidate for future emission spectroscopy to probe for a thermal inversion.
Friends and Foes: Conditional Occurrence Rates of Exoplanet Companions and Their Impact on Radial Velocity Follow-up Surveys
Authors: He Matthias Y. , Ford Eric B. , Ragozzine Darin 
Published: October 2021

Abstract
Population studies of Kepler's multiplanet systems have revealed a surprising degree of structure in their underlying architectures. Information from a detected transiting planet can be combined with a population model to make predictions about the presence and properties of additional planets in the system. Using a statistical model for the distribution of planetary systems, we compute the conditional occurrence of planets as a function of the period and radius of Kepler-detectable planets. About half (0.52 ± 0.03) of the time, the detected planet is not the planet with the largest semi-amplitude (K) in the system, so efforts to measure the mass of the transiting planet with radial velocity (RV) follow up will have to contend with additional planetary signals in the data. We simulate RV observations to show that assuming a single-planet model to measure the K of the transiting planet often requires significantly more observations than in the ideal case with no additional planets, due to systematic errors from unseen planet companions. Our results show that planets around 10 day periods with K close to the single-measurement RV precision (σ
1,obs) typically require ∼100 observations to measure their K to within 20% error. For a next generation RV instrument achieving σ
1,obs = 10 cm s−1, about ∼200 (600) observations are needed to measure the K of a transiting Venus in a Kepler-like system to better than 20% (10%) error, which is ∼2.3 times as many as would be necessary for a Venus without any planetary companions.
Severe form of the hydrothorax associated with right divided atrium and Cytomegalovirus infection - Prenatal diagnosis and outcomes
Authors: Bejiqi Ramush , Retkoceri Ragip , Bejiqi Hana , Zeka Naim , Gerguri Abdurrahim , Vuçiterna Armend , Mustafa Aferdita , Maloku Arlinda , Bejiqi Rinor 
Published: October 2021

Abstract
Fetal hydrothorax (FH) or pleural effusion is a clinical entity, and refers to accumulation of fetal pleural fluid, which may presents a wide spectrum of severity ranging from small, harmless effusion, to life-threatening thoracic compression (1). The perinatal mortality associated with pleural effusion is at least 50 %. Cardiac and extra-cardiac abnormalities may accompany the hydrothorax and their presence also affects the prognosis (2).
Division of the right atrium, first reported in 1868, also known as cor triatriatum dexter, is extremely a rare congenitally abnormality, in which persistence of right valve of the embryonic systemic venous sinus divides the right atrium into two chambers. The embryonic valvar structures, whose significance during fetal life is to direct the richly oxygenated inferior caval venous blood across to the left atrium and thence to the aorta, normal regress in late fetal life and early childhood.
Cytomegalovirus (CMV) is a common human virus, member of herpes virus family, and the most common cause of intrauterine infection, occurring in 0.2 % to 2.2 % of life births (3,4). This report describes antenataly diagnosed a case of a divided right atrium, associated with severe form of hydrothorax and Cytomegalovirus infection.
Here we present a fetus with sever hydrothorax associated with divided right atrium and cytomegalovirus infection.
Génocide ouïghour : cheminement d’un projet colonial
Authors: Reyhan Dilnur 
Published: October 2021

Le premier trimestre 2021, les parlements de sept pays occidentaux ont reconnu que la Chine mène un génocide contre les Ouïghours. Une résolution a été déposée avant l’été à l’Assemblée nationale en France dans ce sens. Que se passe-t-il entre l’État chinois et la population ouïghoure ? Pourquoi parle-t-on aujourd’hui de génocide ? Quel est le fond du conflit sino-ouïghour ? J’essaierai de répondre dans cet article à ces questions en expliquant le processus colonial mis progressivement en place qui s’est fortement aggravé au cours de ces dernières décennies et qu’on peut qualifier de développement totalitaire mariant parfaitement un système dictatorial de type « stalinien » et une économie capitaliste « sauvage » propre au régime chinois actuel. A partir de la théorie de « colonisation du peuplement » développée dans la dernière décennie, j’analyserai ici le cas de la Région ouïghoure afin de démontrer le processus du génocide en cours qui est le résultat d’un long projet colonial.
Le gouvernement fédéral américain au chevet de l’assurance santé
Authors: Beaussier Anne-Laure 
Published: October 2021

Pour beaucoup d’observateurs des politiques de santé des États-Unis, les 28 millions de personnes restant privées d’assurance maladie en 2020, dix ans après l’adoption de l’Obamacare, la réforme du système de santé emblématique du premier mandat de Barack Obama, constituent une démonstration d’échec, appelant à une réforme de la réforme. L’Affordable Care Act (ACA) avait pourtant fait le pari qu’il était possible, avec les bons instruments réglementaires et incitatifs, non seulement de soutenir et de reconstruire un marché des assurances santé qui semblait au bord de l’explosion mais également de l’inciter à endosser des objectifs de service public et de bien commun. Dix ans plus tard cependant, les limites de la réforme, à la fois en termes de couverture de la population et en termes de maîtrise des dépenses de santé alimentent de nombreuses critiques. Cette contribution revient sur la stratégie suivie par l’ACA. Elle explicite ses principaux instruments, analyse les difficultés rencontrées lors de leur mise en œuvre et discute les alternatives envisagées aujourd’hui tant du côté démocrate que du côté républicain.
Bricoler une action municipale de santé à faible coût ou rebâtir des solidarités organisées ? Regard sur la diversité des « mutuelles communales »
Authors: Comer Clémentine 
Published: October 2021

À partir du cas des « mutuelles communales », contrats de complémentaire santé à tarif préférentiel proposés par les élus locaux à leurs administrés, cet article examine l’élargissement à bas coût de l’intervention sociale des municipalités. Il rend en cela compte de bricolages et d’expérimentations de la part de pouvoirs publics locaux pourtant dépourvus de compétences en matière de couverture d’assurance maladie. Parce qu’il répond à un projet citoyen et social plus ou moins porté politiquement, s’insère dans les réseaux locaux d’acteurs de l’assurance, et rencontre une offre commerciale que se disputent mutuelles territoriales, réseaux de courtiers et grandes compagnies d’assurance, le déploiement des mutuelles communales donne à voir des configurations d’action publique contrastées, tant du point de vue de la portée solidaire des dispositifs que de leur pérennité économique.
Bibliometric analysis of the journal Materiales de Construcción: 2013-2020
Authors: Mochón-Bezares G. , Sorli-Rojo Á. 
Published: October 2021

The objective of this study was to carry out an analysis of different bibliometric indicators of the journal Materiales de Construcción to verify the development of its scientific production between the years 2013 and 2020. The authors and their work institutions were analysed to check their productivity and degree of collaboration achieved, the levels of citation obtained in four impact indicators (Journal Impact Factor, 5-Year Impact Factor, Scimago Journal Rank and CiteScore) and the members of the editorial team of the journal to verify their permanence. The results show a high rate of collaboration between authors but somewhat scarce if considered by their work institutions, a significant increase in all the impact indicators consulted, and a reduction in the number of members of the editorial team. It is concluded that Materiales de Construcción journal has increased its internationality and considerably improved its impact between 2013 and 2020.
A desinformação no Brasil durante a pandemia de Covid-19:
Authors: Gehrke Marília , Benetti Marcia 
Published: October 2021

Este artigo apresenta os principais temas, plataformas e atores envolvidos na disseminação de desinformação sobre a Covid-19 no Brasil. Analisamos 407 textos classificados como falsos pelas agências de fact-checking que integram a plataforma colaborativa Latam Chequea Coronavirus. O corpus se refere ao início da pandemia, e por isso inclui conteúdos publicados de 15 de março a 21 de julho de 2020. Por meio de análise de conteúdo, descobrimos que o tópico mais frequente é a política (25,55%), seguido de cura (20,64%), dados (19,66%) e contágio (18,43%). Em relação aos sentidos das publicações, obtidos por meio de análise qualitativa de 300 textos, identificamos que as principais narrativas buscam favorecer o presidente Jair Bolsonaro e suas convicções a respeito da pandemia. Praticamente a metade dos casos (48,34%) utiliza, como estratégia, a produção de falso contexto, quando uma imagem genuína ou um fato verdadeiro é deslocado de seu contexto original para gerar uma inverdade. Também estão no entorno do presidente os atores que com frequência espalham desinformação sobre a pandemia nas redes sociais digitais. Em 60 textos nos quais foi possível identificar os atores com potencial de ampliar a profusão de conteúdo falso, o deputado federal Osmar Terra se apresenta como uma figura central, ao lado de Bolsonaro e seus filhos. Nosso levantamento ainda mostra que a desinformação circula principalmente no Facebook e no WhatsApp, muitas vezes simultaneamente nesses espaços e em outras redes sociais. Texto e imagem são os formatos mais recorrentes.

Palavras-chave: jornalismo; desinformação; Covid-19
Fissuras no Poder Algorítmico: plataformas, códigos e contestação
Authors: Ferrari Fabian , Graham Mark 
Published: October 2021

Plataformas digitais de trabalho não tentam construir relações fortes e de confiança entre trabalhadores, clientes e plataforma. Em vez disso, as plataformas utilizam uma dupla articulação do poder algorítmico para governar forças de trabalho espacialmente dispersas em sentidos materiais e discursivos. Entretanto, os algoritmos não têm resultados hegemônicos e não retiram totalmente a agência dos trabalhadores das plataformas. Por meio de manipulação, subversão e ruptura, os trabalhadores trazem as fissuras desse poder algorítmico para sua ação. As fissuras no poder algorítmico são momentos em que os algoritmos passam a não governar como foi pretendido. Embora esses momentos não sejam resultados simples e positivos para os trabalhadores, eles mostram como o poder algorítmico é inerentemente apenas parcial.
Palavras-chave: poder algorítmico; trabalho por plataformas; gig economy; manipulação; subversão; ruptura.