bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simulation design and students’ satisfaction with home‐based simulation learning in oral health therapy
Authors: Tan Sharon Hui Xuan , Ansari Anshad , Ali Noohu Mohamed Irfan , Yap Adrian Ujin 
Published: March 2021

AbstractObjectivesThe COVID‐19 pandemic presents a challenging situation for dental education, with school closures worldwide. While practical sessions are important for the acquisition of clinical skills, few studies have examined the role of home‐based simulation learning (HBSL). This study aims to identify key aspects of simulation design and factors associated with students’ satisfaction with HBSL.MethodsDuring a “circuit‐breaker” period in Singapore, the Nanyang Polytechnic School of Health & Social Sciences (Oral Health Therapy) distributed portable manikins and instruments to students and staff for use at home. Synchronous teaching sessions with real‐time feedback were carried out over the Zoom teleconferencing platform. A cross‐sectional survey of students was conducted after 3 weeks of the HBSL program. Multiple linear regression analyses were carried out to assess the association between satisfaction with domains of simulation design and overall satisfaction with HBSL.ResultsThe top three factors of importance to students in HBSL were feedback and guided reflection, support, and objectives and information. Final‐year students expressed higher levels of overall satisfaction and self‐confidence following HBSL than first‐year students. Satisfaction with the objectives (β = 0.42, 95% CI 0.26–0.57), support (β = 0.27, 95% CI 0.11–0.42), and problem‐solving (β = 0.28, 95% CI 0.10–0.46) domains in the Simulation Design Scale were positively associated with overall student satisfaction and self‐confidence in learning.ConclusionThe findings can aid educators in the design of future HBSL programs, with a focus on areas of simulation design that are of importance to students.
Treatment of medication‐related osteonecrosis of the jaw using segmental mandibulectomy and a reconstruction plate: A case report and 5‐year follow‐up
Authors: Kamaguchi Mayumi , Ohga Noritaka , Hata Hironobu , Yoshikawa Kazuhito , Sakata Ken‐Ichiro , Asaka Takuya , Sato Jun , Kitagawa Yoshimasa 
Published: March 2021

AbstractMedication‐related osteonecrosis of the jaw (MRONJ) has been commonly known as a adverse side effect of antiresorptive or antiangiogenic agents for the treatment of osteoporosis patients. Although there is considerable evidence on the occurrence of MRONJ in the literature, the number of studies focusing on Stage 3 MRONJ attributable to oral administration of bisphosphonates (BPs) in patients with osteoporosis is limited. The patient had exposed necrotic bone in the mandible and pus discharge through an extraoral fistula attributed to an oral BPs for the treatment of steroidal osteoporosis. She was diagnosed with Stage 3 MRONJ. She had no other identifiable cause of mandible necrosis. Given the severity and risk of pathological fractures of the mandibular bone, an extensive surgical therapy was performed after failure of compressive conservative therapy. Our surgical treatment satisfied the patient with regard to esthetics, leading to a dramatic improvement in her quality of life for 5 years after surgery. We report a case of Stage 3 MRONJ associated with BP administration for steroid‐induced osteoporosis and discuss esthetically successful reconstruction of the mandible using mandibular reconstruction plates following segmental mandibulectomy. To prevent such severe complications, it is important to develop appropriate medical and surgical treatment strategy for immunosuppressed patients with osteoporosis.
Nudges Don't Work When the Benefits Are Ambiguous: Evidence from a High‐Stakes Education Program
Authors: Castleman Benjamin L. , Murphy Francis X. , Patterson Richard W. , Skimmyhorn William L. 
Published: March 2021

AbstractThe Post‐9/11 GI Bill allows service members to transfer generous education benefits to a dependent. We run a large‐scale experiment that encourages service members to consider the transfer option among a population that includes individuals for whom the transfer benefits are clear and individuals for whom the net‐benefits are significantly more ambiguous. We find no impact of a one‐time e‐mail about benefits transfer among service members for whom we predict considerable ambiguity in the action, but sizeable impacts among service members for whom education benefits transfer is far less ambiguous. Our work contributes to the nascent literature investigating conditions when low‐touch nudges at scale may be effective.
Effects of annealing constraint methods on poly(L‐lactic acid) monofilaments for application in stents annealing
Authors: Li Xin , Tian Yuan , Zhang Jing , Cheng Jie , Wu Gensheng , Zhang Yi , Zhao Gutian , Ni Zhonghua 
Published: March 2021

AbstractMechanical properties of poly(L‐lactic acid) (PLLA) braided stents are closely related to the performance of the weaving monofilaments. In this study, the PLLA monofilaments were prepared via solid‐state drawing (SSD) method and annealed with different constraint methods. Experimental results show that mechanical properties of fabricated monofilaments have been greatly improved by SSD method. With the constrained annealing method, mechanical properties can be further improved while negative effect is shown with unconstrained annealing method. The physicochemical properties of PLLA monofilaments were further characterized, and it is found that the draw ratio of SSD and annealing method can affect the crystallinity and crystallite size, which can directly influence the mechanical properties of the monofilaments. This work tells that it is necessary to consider collectively the effects of SSD method and annealing method of the monofilaments in order to obtain optimized mechanical properties of the braided stents.
Investigating the criticality of user‐reported issues through their relations with app rating
Authors: Di Sorbo Andrea , Grano Giovanni , Aaron Visaggio Corrado , Panichella Sebastiano 
Published: March 2021

AbstractApp quality impacts user experience and satisfaction. As a consequence, both app ratings and user feedback reported in app reviews are directly influenced by the user‐perceived app quality. Through an empirical study involving 210,517 reviews related to 317 Android apps, in this paper, we experiment with the combined usage of app rating and user reviews analysis (i) to investigate the most important factors influencing the perceived app quality, (ii) focusing on the topics discussed in user review that most relate with app rating. Besides, we investigate whether specific code quality metrics could be monitored to prevent the rising of negative user feedback (i.e., types of user review comments), connected with low ratings. Our study demonstrates that user comments reporting bugs are negatively correlated with the rating, while reviews reportingfeature requests do not. Interestingly, depending on the app category, we observed that different kinds of issues have rather different relationships with the rating and the user‐perceived quality of the app. In particular, we observe that for specific app categories (e.g., communication), some code quality factors have significant relationships with the raising of certain types of feedback, which, in turn, are negatively connected with app ratings.
On the mechanism of three-body adhesive wear in turning
Authors: Svenningsson Inge , Tatar Kourosh 
Published: March 2021

AbstractThe paper reveals a hypothesis regarding the adhesive mechanism in metal cutting and its mechanical dynamics. One steel grade, 34CrNiMo 6, 285 HB, and one set of coatings on the cutting tool are reviewed. The adhesive mechanism is a transient vibration, including a feedback system limited by the plastic deformation in the chip. The vibration shows as a cluster of waves with stochastic duration in time. It starts up again after a stochastic lapse of silence. The cycle frequency is around 12.5 kHz and the internal excitation is twice that frequency, as the cutting speed and feed are 200 m/min and 0.2 mm, respectively. The adhesive frequency and amplitude are influenced by the cutting speed and the current wear status. The adhesion is monitored by the sound waves emanating from vibrations in the chip, the part still in the workpiece.
A qualitative evaluation of a nurse-led pre-operative stoma education program for bladder cancer patients
Authors: Wulff-Burchfield Elizabeth Marie , Potts Maryellen , Glavin Katherine , Mirza Moben 
Published: March 2021

Abstract
Introduction
Radical cystectomy remains the standard of care for muscle-invasive bladder cancer and high-risk non-muscle-invasive bladder cancer. Postoperative ostomy education is common, but patients struggle to maintain self-management practices. A preoperative ostomy education program was developed to meet this need, and we conducted a qualitative study with participating patient-caregiver dyads to evaluate the educational and psychosocial impacts of the program and examine alignment with program objectives.

Materials and methods
A qualitative descriptive study was conducted utilizing a thematic analysis approach. Sixteen patients, eighteen caregivers, and three program educators completed semi-structured interviews from 3 to 18 months post the program. Interviews were audio-recorded and transcribed. Thirteen end-of-course surveys from the initial educational program cohort were transcribed, coded, analyzed; this data was triangulated with patient, caregiver, and educator interviews.

Results
Analysis uncovered three themes: (1) Patient and caregiver motivation to attend the program, (2) attitudes toward this life-changing event, and (3) education. For theme 1, patients and caregivers cited lack of knowledge, fear, and concern about ostomy surgery and care as motivation. For theme 2, there were a variety of attitudes toward the ostomy, ranging from avoidance to acceptance, and a similar breadth of attitudes toward caregiving, with some patients and caregivers describing ongoing dependence and other patients seeking complete independence. For theme 3, the interactive curriculum was determined to be effective, and the patient advocate was cited as the most memorable program component.

Conclusions
A formal preoperative ostomy education program employing an interactive educational approach and featuring a patient advocate can prepare bladder cancer patients and caregivers for ostomy self-management and post-ostomy life.
Classification and seismic fragility assessment of confined masonry school buildings
Authors: Parammal Vatteri Ahsana , D’Ayala Dina 
Published: March 2021

AbstractSchool buildings being a critical social infrastructure, assessment of their seismic behaviour is of utmost importance in ensuring safe schooling facilities in locations of high seismicity. This study presents two important aspects in analysing any existing building stock for seismic behaviour: the development of an appropriate taxonomy system and an appropriate analytical method to conduct fragility assessment. A detailed desk study of existing schools’ databases and tailored field investigation in Guwahati, Assam, situated in India’s highest seismic zone, reveal that the majority of school buildings can be categorised within the confined masonry (CM) typology. This study discusses first, the addition to the World Bank promoted Global Library of School Infrastructure taxonomy of the specific category relating to CM as to include the buildings under study, which are non-engineered CM buildings with flexible roofs. Identifying the density of confinement and quality of connections as critical parameters for the seismic response of these buildings, varying seismic design levels are defined in relation to these indicators. Secondly, the paper presents an approach for carrying out nonlinear static pushover analysis of these buildings with flexible diaphragms and elaborates on the criteria adopted for determining the performance drift limits in buildings with varying levels of seismic design. Numerical analysis for the capacity assessment of selected index buildings is carried out using a commercial software that enables nonlinear extreme loading analysis. Different failure mechanisms as a function of the level of confinement are identified and the performance range for three damage states for three index buildings is obtained by using the N2 method. The study shows the influence of both choices of performance indicators and intensity measure on the resulting fragility functions. Given the consistency of the educational building stock in Guwahati, the results can be used for investment on retrofit decision making at regional level.
Steam reforming of ethanol for hydrogen production: influence of catalyst composition (Ni/Al2O3, Ni/Al2O3–CeO2, Ni/Al2O3–ZnO) and process conditions
Authors: Shtyka O. , Dimitrova Z. , Ciesielski R. , Kedziora A. , Mitukiewicz G. , Leyko J. , Maniukewicz W. , Czylkowska A. , Maniecki T. 
Published: March 2021

AbstractEthanol steam reforming was studied over Ni supported catalysts. The effects of support (Al2O3, Al2O3–ZnO, and Al2O3–CeO2), metal loading, catalyst activation method, and steam-to-ethanol molar feed ratio were investigated. The properties of catalysts were studied by N2 physisorption, TPD-CO2, X-ray diffraction, and temperature programmed reduction. After activity tests, the catalysts were analyzed by TOC analysis. The catalytic activity measurements showed that the addition either of ZnO SSor CeO2 to alumina enhances both ethanol conversion and promotes selectivity towards hydrogen formation. The same effects were observed for catalysts with higher metal loadings. High process temperature and high water-to-ethanol ratio were found to be beneficial for hydrogen production. An extended catalyst stability tests showed no loss of activity over 50 h on reaction stream. The TOC analysis of spent catalysts revealed only insignificant amounts of carbon deposit.
Metal load and oxidative stress driven by organotin compounds on rainbow trout
Authors: Magara Gabriele , Elia Antonia Concetta , Dörr Ambrosius Josef Martin , Abete Maria Cesarina , Brizio Paola , Caldaroni Barbara , Righetti Marzia , Pastorino Paolo , Scoparo Melissa , Prearo Marino 
Published: March 2021

AbstractTributyltin-based (TBT) antifouling paints, widely used for the treatment of flooded surfaces, have been banned in 2008 for their high environmental persistence and bioaccumulation in aquatic organisms. Although it is still present in aquatic ecosystems, oxidative stress driven by TBT has been still poorly investigated in fish. The aim of the study was to examine the time-course stress responses in liver of rainbow trout that received a single intraperitoneal injection of tributyltin chloride (TBTC) or tributyltin ethoxide (TBTE), both at a dose of 0.05 and 0.5 mg/kg. Levels of metallothioneins, total glutathione, malondialdehyde, superoxide dismutase, catalase, glutathione peroxidase and glutathione S-transferase were evaluated at 3 and 6 days post-injection. Tin load was measured in the muscle of the same fish. Differences were observed in the time-course accumulation of tin with a clear dose-response relationship. Although individual oxidative stress biomarkers varied, the biomarker profile indicated different stress mechanisms caused by both TBTC and TBTE. The weak induction of metal-trapping metallothioneins and the changes of oxidative stress biomarkers suggested a stress-pressure in both TBT-treated trout, advising for an ecotoxicological risk for freshwater ecosystems.
Developing an Efficient Catalyst Based on Thermal and Acid-Treated Clay for the Removal of Trace Olefins From Aromatic Compounds
Authors: Nouri Nooshin , Tasviri Mahboubeh , Ghasemzadeh Hossein 
Published: March 2021

AbstractBentonite is used as a catalyst in the removal of olefins from aromatic compounds and the present study was designed to investigate how its performance might be improved by various treatments. Bentonite from Semnan mine, Iran, was used in the study following initial characterization. In order to investigate the effect of acid and thermal treatments on the removal of olefins from aromatic compounds, bentonite samples were modified using HNO3 at different concentrations (0.15, 0.3, 0.5, 0.7, 1, and 2 M) and were also at temperatures between 100 and 340°C for 3 h. To examine the catalytic activity of bentonite-based catalysts, the samples were evaluated after running batch and continuous experiments. The optimum catalyst was characterized using thermo-programmed desorption (TPD) of NH3 to examine the acidic sites. Scanning Electron Microscopy (SEM) images, nitrogen adsorption-desorption isotherms (BET analysis), and X-ray diffraction (XRD) patterns were used to study the structural changes of the bentonite produced by the acid and thermal activation. The removal of olefins by the catalysts in batch and continuous systems revealed that the sample modified with 0.3 M Nitric acid at 150°C had superior catalytic activity, with olefin conversion remaining at >50% for up to 20 h. Nitrogen adsorption-desorption isotherms showed that acid treatment can produce a mesoporous structure. On the other hand, the TPD analysis indicated that during weak acid treatment, some cations, such as Al3+ and Fe3+, were leached from octahedral sheets and the interlayers of the clay mineral resulting in weak acid sites being generated. Finally, a novel method was proposed and tested for measuring the Bromine Index (BI) using potentiometric titration.
Tuning in to his-story: an account of radio in Ghana through the experience of B. S. Gadzekpo
Authors: Gadzekpo Audrey 
Published: March 2021

AbstractThis article introduces a personalized account of the early years of radio in Ghana based on an unpublished manuscript by one of its pioneering broadcasters – Bernard Senedzi (B. S.) Gadzekpo. An accomplished writer who produced manuscripts in both English and the Eʋe language, Gadzekpo's radio memoir is written from the vantage point of someone who worked in both the colonial and postcolonial broadcast service for nearly thirty years. It foregrounds African broadcasters in the history of radio and offers insights into the complex realities of Africa's mutable encounter with radio and the strategic role played by local intellectuals in fulfilling its modernization mission during and after the colonial period.
Philippa Foot, l'utilitarisme et la promesse
Authors: Boyer Vincent 
Published: March 2021

RÉSUMÉDans cet article, nous revenons sur la critique tout à fait originale de l'utilitarisme que Philippa Foot propose dans son œuvre de philosophie morale. Nous montrerons que la confrontation avec cette théorie éthique normative fut l'une des causes qui conduisit la philosophe britannique à reprendre à nouveaux frais la notion de rationalité pratique dans la dernière partie de son œuvre, notamment lors de la discussion qu'elle engage avec l'utilitarisme sur le fondement de l'obligation des promesses dans son livre de 2001,Le Bien naturel.
La disparition des formes aristotéliciennes. À propos d'une démarche clandestine dans les Méditations
Authors: Moyal Georges 
Published: March 2021

RÉSUMÉMême si l'appréhension que l'on peut avoir des formes aristotéliciennes résulte de ce qu'Aristote nomme «induction», rien ne nécessite que leurs composantes soient reliées entre elles de façon intelligible, comme le sont, au contraire, les propriétés de la matière. C'est ce qui porte René Descartes à en débarrasser les sciences par une démarche effectuée subrepticement dans sa VIe Méditation, et à leur substituer la matière, dénominateur commun des êtres naturels. C'est cette démarche — elle continue d’éluder certains de ses lecteurs —, que nous tentons de mettre au jour dans ce qui suit.
La nécessité du mouvement éternel. Note exégétique à Aristote, Physique VIII, 5, 256b8-13
Authors: Gili Luca , Godin-Tremblay Laurence 
Published: March 2021

RÉSUMÉEn Physique VIII, 5, 256b8-13, Aristote soutient qu'il est impossible qu'il n'y ait pas de mouvement, parce qu'il a démontré auparavant qu'il est nécessaire qu'il y ait toujours du mouvement. En effet, en Physique VIII, 1, 251b23-28, Aristote avait dit qu'il est nécessaire (necessitate consequentiae) que si le temps est éternel, le mouvement le soit aussi. En Physique VIII, 5, 256b8-13, Aristote introduit en revanche la nécessité du mouvement éternel de sensu diviso. Dans cette note, nous montrons que l'argument de Physique VIII, 1, 251b23-28 implique aussi la nécessité du mouvement éternel de sensu diviso.
Aberrant Gcm1 expression mediates Wnt/β-catenin pathway activation in folate deficiency involved in neural tube defects
Authors: Li Jianting , Xie Qiu , Gao Jun , Wang Fang , Bao Yihua , Wu Lihua , Yang Lihong , Liu Zhizhen , Guo Rui , Khan Ajab , Dan Liu  , Li Caihua , Wu Jianxin , Xie Jun 
Published: March 2021

AbstractWnt signaling plays a major role in early neural development. An aberrant activation in Wnt/β-catenin pathway causes defective anteroposterior patterning, which results in neural tube closure defects (NTDs). Changes in folate metabolism may participate in early embryo fate determination. We have identified that folate deficiency activated Wnt/β-catenin pathway by upregulating a chorion-specific transcription factor Gcm1. Specifically, folate deficiency promoted formation of the Gcm1/β-catenin/T-cell factor (TCF4) complex formation to regulate the Wnt targeted gene transactivation through Wnt-responsive elements. Moreover, the transcription factor Nanog upregulated Gcm1 transcription in mESCs under folate deficiency. Lastly, in NTDs mouse models and low-folate NTDs human brain samples, Gcm1 and Wnt/β-catenin targeted genes related to neural tube closure are specifically overexpressed. These results indicated that low-folate level promoted Wnt/β-catenin signaling via activating Gcm1, and thus leaded into aberrant vertebrate neural development.
Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells
Authors: Baek Dawoon , Park Kwang Hwan , Lee Kyoung-Mi , Jung Sujin , Joung Soyeong , Kim Jihyun , Lee Jin Woo 
Published: March 2021

AbstractThe ubiquitin protease pathway plays important role in human bone marrow-derived mesenchymal stem cell (hBMSC) differentiation, including osteogenesis. However, the function of deubiquitinating enzymes in osteogenic differentiation of hBMSCs remains poorly understood. In this study, we aimed to investigate the role of ubiquitin-specific protease 53 (USP53) in the osteogenic differentiation of hBMSCs. Based on re-analysis of the Gene Expression Omnibus database, USP53 was selected as a positive regulator of osteogenic differentiation in hBMSCs. Overexpression of USP53 by lentivirus enhanced osteogenesis in hBMSCs, whereas knockdown of USP53 by lentivirus inhibited osteogenesis in hBMSCs. In addition, USP53 overexpression increased the level of active β-catenin and enhanced the osteogenic differentiation of hBMSCs. This effect was reversed by the Wnt/β-catenin inhibitor DKK1. Mass spectrometry showed that USP53 interacted with F-box only protein 31 (FBXO31) to promote proteasomal degradation of β-catenin. Inhibition of the osteogenic differentiation of hBMSCs by FBXO31 was partially rescued by USP53 overexpression. Animal studies showed that hBMSCs with USP53 overexpression significantly promoted bone regeneration in mice with calvarial defects. These results suggested that USP53 may be a target for gene therapy for bone regeneration.