bluuebunny/crossref_metadata_2025_split huggingface dataset:
Statistical model for prediction of ABO hemolytic disease of the fetus and newborn in India
Authors: Patale D.S. , Lokhande T.L. , Chaudhary R.K. 
Published: June 2021

Abstract
ABO incompatibility is the most common cause of immune hemolytic disease of the fetus and newborn (HDFN). The American Academy of Pediatrics lists blood group incompatibility as one of the major risk factors for severe hyperbilirubinemia in newborns. We have estimated the risk of ABO HDFN to determine the need for its routine screening. Blood group data from all blood donors who donated in the last 10 years were collected and analyzed. The population prevalence of ABO blood group genes using the phenotype data of blood donors was estimated. This information was further used to calculate an incidence of ABO HDFN requiring intervention in the population. ABO blood group typing was analyzed in 425,743 blood donors. The ABO phenotypes of A, B, O, and AB were 22.48, 36.73, 31.59, and 9.2 percent, respectively. The gene frequencies were 0.1733, 0.2647, and 0.5620 for A, B, and O, respectively. It was estimated that 13.84 percent of group O women would give birth to a non–group O baby and that approximately 2.77 percent of deliveries would likely have ABO HDFN in the study population. In India, the estimated risk of ABO HDFN is 2.9 percent, with a daily 2196 babies at risk of ABO HDFN requiring intervention. This analysis estimates the overall burden of ABO HDFN in the population, which could aid in the decision-making of policymakers, physicians, and community health practitioners to improve neonatal care.
Anti-A1Leb: a mind boggler
Authors: Gupta A. , Chaudhary K. , Asati S. , Kakkar B. 
Published: June 2021

Abstract
The Lewis blood group system is unique because antigens are neither alleles of the same gene nor are they synthesized by red blood cells (RBCs); rather, they are adsorbed onto the RBC membrane from plasma as glycolipids. Antibodies against Lewis antigens are predominantly naturally occurring immunoglobulin (Ig)M type that sometimes react at 37°C and the antihuman globulin phase. Lewis compound antigens, ALeb and BLeb, have been described that were confirmed because of the presence of antibodies against them. These compound antigens are the result of an interaction between ABO, H, SE, and LE genes.
Warming of water temperature in spring and nutrient release from sediment in a shallow eutrophic lake
Authors: Shinohara Ryuichiro , Tsuchiya Kenji , Kohzu Ayato 
Published: June 2021

AbstractWe investigated whether recent springtime water temperature increases in a shallow eutrophic lake affected bottom sediment temperature and fluxes of ammonia (NH4+) and phosphate (PO43−) from the sediment. We conducted a lake-wide survey of Lake Kasumigaura, Japan, and analyzed the relationship between water temperature increases in spring and NH4+ and PO43− release fluxes. We also developed a numerical model to analyze how water temperature increase affects sediment temperature. Water temperature in May increased during 2010–2019 at a rate of 1.8–3.2 °C decade−1. The numerical simulation results showed that the water temperature increase was accompanied by a sediment temperature increase from a minimum of 18.3 °C in 2011 to a maximum of 21.6 °C in 2015. Despite the substantial difference in the observed sediment temperature (2.9 °C), no significant differences in NH4+ and PO43− fluxes in May between 2013/2014 and 2015 were found. These results suggest that both water and sediment temperatures are increasing in Lake Kasumigaura in spring, but it is unclear whether this warming has affected NH4+ and PO43− releases from the sediment. However, because a nonlinear response to sediment temperature was observed, future springtime warming may accelerate NH4+ and PO43− releases.
Evaluation of Best Management Practices for non-point source pollution based on the SWAT model in the Hanjiang River Basin, China
Authors: Li Shu , Li Jiake , Hao Gairui , Li Yajiao 
Published: June 2021

Abstract
Taking the Hanjiang River Basin with the Ankang hydrological station as the control section and as the study area, the Soil and Water Assessment Tool (SWAT) model was used to identify the spatial and temporal distribution of non-point source (NPS) pollution and determine the critical source areas (CSA). We set up 11 Best Management Practices (BMPs) in the CSA and evaluated their environmental and comprehensive benefits. The results showed that TN and TP loads in flood season were significantly higher than that in the non-flood season. The distribution of loss intensity of TN and TP load has a strong correlation with runoff and sediment erosion intensity, respectively. Among the eight individual BMPs, the reduction rates of stubble coverage, grassed waterway and returning farmland to forest land were relatively high, and the comprehensive attribute value Z of stubble coverage was the highest. Among the three combined BMPs, the reduction rate of ‘stubble coverage + grassed waterway + returning farmland to forest land (&gt;25°)’ was the highest and the Z value was the largest. Overall, the BMPs such as stubble coverage, grassed waterway, and returning farmland to forest land can be adopted alternately to control NPS pollution in the Hanjiang River Basin.
Efficient removal of acetic acid by a regenerable resin-based spherical activated carbon
Authors: Wu Huiling , Sun Wenjing , Wei Huangzhao , Zhao Ying , Jin Chengyu , Yang Xu , Rong Xin , Sun Chenglin 
Published: June 2021

Abstract
Carboxylic acids are the main pollutant of industrial wastewater during the advanced oxidation process (AOPs). In this study, a resin-based spherical activated carbon (RSAC, AF5) as an adsorbent was examined and acetic acid was used as a model substrate for adsorption investigation. The pH = 3, temperature = 298 K were fixed by batch technique. The pseudo-second-order kinetic model, the intraparticle and external models are fitted well, and it was found that the adsorption of acetic acid onto AF5 was controlled by liquid film diffusion. A Freundlich model indicated that the adsorption process was heterogeneous multimolecular layer adsorption on the surface. AF5 shows good regenerative ability; the recovery rate of adsorption capacity was ∼88% after five cycles. Chemical oxygen demand (COD) adsorption removal rate could be maintained at 100% for over 35 h in an actual AOPs effluent, and could be eluted for 100% after 8 h by 0.8wt% NaOH. Characterizations, including XRF, XRD, TG/DSC,FTIR, SEM and N2 adsorption, showed that the excellent adsorption performance was mainly due to the microporous structure and large specific surface area (1,512.88 m2/g), the adsorption mechanism mainly included pore filling effect and electrostatic attraction. After five adsorption recycles, AF5's pore characteristic did not change significantly. This study provides a scientific basis for the wastewater standard discharge process of AOPs coupled adsorption.
Prevention of Mother-to-child HIV Transmission in Nigeria: Six Years’ Experience from a Tertiary Institution
Authors: Jalo Rabiu Ibrahim , Amole Taiwo Gboluwaga , Dongarwar Deepa , Abdullahi Hadiza Musa , Tsiga-Ahmed Fatimah Ismail , Gaya Sule Abdullahi , Bello Musa Mohammed , Bashir Usman , Aminu Aliyu , Kwaku Aminatu Ayaba , Aliyu Muktar Hassan , Salihu Hamisu Mohammed , Galadanci Hadiza Shehu 
Published: June 2021

Background:
In line with global standards and progress made in Prevention of Motherto-
Child Transmission (PMTCT), an assessment of the outcome of Early Infant Diagnosis in northern
Nigeria is necessary to evaluate progress towards zero Human immunodeficiency Virus (HIV)
infection among children.

Objectives:
This study assessed the infection rate and risk factors for mother-to-child HIV transmission
among HIV-exposed children in Kano, northwest Nigeria.

Method:
Using a retrospective cohort design, pregnant HIV-positive women and their exposed infants
were recruited over a period of six years (2010 to 2016). Participants were enrolled during
pregnancy or at delivery in the PMTCT clinic of a tertiary health facility in Kano, Nigeria. The
main outcomes for the study were Early infant diagnosis positivity for HIV at 6 weeks and risk factors
for positivity.

Results:
Of the 1,514 infants studied, early infant diagnosis was positive for HIV among 13 infants
(0.86%). Infants whose mothers did not have antiretroviral therapy (adjusted Prevalence Ratio aPR
= 2.58, 95%CI (1.85- 3.57)), who had mixed feeding (aPR = 12.06, 95%CI (9.86- 14.70)), and
those not on antiretroviral prophylaxis (aPR = 20.39, 95%CI (16.04- 25.71)) were more likely to be
infected with HIV. HIV-exposed infants on nevirapine and zidovudine prophylaxis were 95% and
74%, respectively, less likely to be infected with HIV.

Conclusion:
HIV infection rate remains high among HIV-exposed infants whose mothers did not
receive PMTCT services. Scaling up proven interventions of early commencement of antiretroviral
treatment for mothers, adherence to antiretroviral prophylaxis, and avoidance of mixed feeding
among HIV-exposed infants would protect future generations from HIV infection.
ZnCl2/PhI=O Mediated Selective ortho-Chlorination of Amides
Authors: Liu Haixuan , Sha Qiang 
Published: June 2021

Abstract:A new ortho-chlorination system consisting of zinc(II) and hypervalent iodine(III) reagent was developed for ortho-chlorination of amides, and the desired products were obtained in moderate to good yields (38-85%). This highly facile and convenient methodology is tolerant of aromatic amide and alkyl amide with diverse substituted groups. A plausible mechanism has been illustrated, in which carbocation rearrangement and metal salt coordinate facilitated orthochlorination are involved.
Emergence of the First Strains of SARS-CoV-2 Lineage B.1.1.7 in Romania: Genomic Analysis
Authors: Lobiuc Andrei , Dimian Mihai , Sturdza Olga , Filip Roxana , Covasa Mihai 
Published: June 2021

Background
The United Kingdom reported the emergence of a new and highly transmissible SARS-CoV-2 variant (B.1.1.7) that rapidly spread to other countries. The impact of this new mutation—which occurs in the S protein—on infectivity, virulence, and current vaccine effectiveness is still under evaluation.

Objective
The aim of this study is to sequence SARS-CoV-2 samples of cases in Romania to detect the B.1.1.7 variant and compare these samples with sequences submitted to GISAID.

Methods
SARS-CoV-2 samples were sequenced and amino acid substitution analysis was performed using the CoV-GLUE platform.

Results
We have identified the first cases of the B.1.1.7 variant in samples collected from Romanian patients, of which one was traced to the region of the United Kingdom where the new variant was originally sequenced. Mutations in nonstructural protein 3 (Nsp3; N844S and D455N) and ORF3a (L15F) were also detected, indicating common ancestry with UK strains as well as remote connections with strains from Nagasaki, Japan.

Conclusions
These results indicate, for the first time, the presence and characteristics of the new variant B.1.1.7 in Romania and underscore the need for increased genomic sequencing in patients with confirmed COVID-19.
Effectiveness of hepatitis B hyperimmunglobulin and vaccine in preventing perinatal transmission in children born from a mother with chronic B hepatitis
Authors: Kahveci Feyza Gökben , Civan Hasret Ayyildiz , Salihoğlu Özgül 
Published: June 2021

Background. Viral hepatitis is still one of the important health problems all over the world today. Hepatitis B is a life-threatening liver infection that can cause chronic infections. It increases the risk of death from cirrhosis and hepatocellular carcinoma. One of the most important factors in chronic or acute hepatitis B infection is the age of infection. The earlier the virus is encountered, the greater the risk of chronicity of the disease. Prevention of perinatal transmission of the disease is of great importance. The most effective way to control hepatitis B infection is to prevent contamination and ensure immunity. There is a safe and effective vaccine available that provides 98–100% protection against hepatitis B. Prevention of hepatitis B infection control the development of complications, including chronic disease and liver cancer. The purpose of this study is to evaluate the efficacy of the vaccine and hepatitis immunoglobulin administered to prevent perinatal hepatitis B infection transmission in babies born to mothers with chronic hepatitis B infection. Materials and methods. Fifty-five children born to mothers with chronic hepatitis B infection in our hospital between January 1, 2013 and January 1, 2019 and accepted to participate in the study were included in our study. In retrospective file examination, maternal gestational age, maternal hepatitis B test, delivery method, baby birth weight, baby birth week, whether immunoglobulin and hepatitis B vaccine were administered to these babies in the first 24 hours after birth, hepatitis B vaccine and immunoglobulin administration time, bathroom status, infant hepatitis B tests, additional studies on the child’s viral diseases (hepatitis C, human immunodeficiency virus) and the baby’s liver transaminase tests (aspartate aminotransferase, alanine aminotransferase) were evaluated. The vaccination program of the baby, the control of the mother’s hepatitis B status, the time of the breast milk intake, the height and weight of the baby, the follow-up of the mother during pregnancy and the drug use status were collected. Children previously diagnosed with chronic B hepatitis were excluded from the study. Results. Hepatitis B surface antigen tests were positive in two infants who received three doses of hepatitis B vaccine. The mothers of both of these babies were positive for hepatitis B surface antigen and hepatitis B envelope antigen. Forty-three (78.2 %) patients had a protective antibodies to hepatitis B surface antigen, while 12 (21.8 %) didn’t have it. Conclusions. Hepatitis B serology should be checked in women who live in countries with high risk of chronic hepatitis B infection and who are pregnant, and babies born to these mothers should have hepatitis B vaccine and immunoglobulin.
Assessment of the trophological status of children with rheumatic diseases
Authors: Omelchenko L.I. , Mukvich O.M. , Belskaya E.A. , Dudka I.V. , Ludvik T.A. 
Published: June 2021

Background. Analyzing modern medical literature, it can be noted that in pediatric rheumatology, insufficient attention is paid to assessing the trophological status of sick children. Purpose: to investigate the nutritional status of children with various nosological forms of rheumatic diseases (RD). Materials and methods. The nutritional status of 35 children with RD was investigated, of which 5 patients had systemic variant of juvenile idiopathic arthritis (JIA), 13 patients had articular form of JIA, 4 patients had systemic lupus erythematosus, 3 patients had mixed connective tissue disease (Sharp’s syndrome), 6 children had juvenile systemic scleroderma, 4 patients had juvenile dermatomyositis. All patients underwent a generally accepted comprehensive clinical, laboratory and instrumental examination. To assess the trophological status, the body mass index and the blood serum leptin were determined by the enzyme immunoassay and the trophological status coefficient was calculated. Results. The results of the conducted studies indicate that trophological insufficiency of varying degrees manifested in 78.5 % of children with RD in a decrease in body weight, depletion of muscle mass, adipose tissue, changes in the skin and its appendages, mucous membranes, organs of vision, oral cavity, cardiovascular system. The most pronounced trophological insufficiency was found in children with systemic JIA, with juvenile scleroderma and dermatomyositis.
Análise do setor cultural e criativo em Portugal: principais estudos macroeconômicos entre 2008-2018
Authors: Cortez Maria Raquel , Teixeira Luis 
Published: June 2021

Em Portugal, datam do início deste milénio os primeiros estudos sobre o setor cultural e criativo e a sua projeção no desenvolvimento do país.Entre 2008 e 2018, vários estudos foram realizados para caracterizar o setor e permitir a implementação de medidas de apoio eficazes. Os diferentes estudos apontam para um contributo crescente do setor para a criação de emprego e de riqueza. Durante a crise económica que o país atravessou, os efeitos negativos verificados forem rapidamente ultrapassados, mostrando o seu dinamismo. A aposta numa formação tecnológica de qualidade e o aumento do turismo têm promovido parcerias e levado à implementação de novos modelos de negócio.Este artigo apresenta os principais estudos realizados em Portugal, destacando os seus objetivos, as metodologias seguidas e limitações, assim como os principais resultados e conclusões.
Indeks Morfologi Tubuh Kambing Peranakan Etawah (PE) di Sentra Pembibitan Kambing Kecamatan Mestong Kabupaten Muaro Jambi
Authors: Wiyanto Eko , Putra Anto Yahya 
Published: June 2021

Penelitian ini dilakukan di Sentra Peternakan Kambing di kecamatan Mestong kabupaten Muaro Jambi selama 6 (enam) bulan. Metode yang digunakan dalam penelitian ini adalah survai. Obyek yang diamati adalah kambing Peranakan Etawah umur lepas sapih (6 bulan). Penentuan sampel dilakukan dengan metode purposive sampling. Tujuan dari penelitian ini adalah mengetahui indeks morfologi ukuran-ukuran tubuh kambing Peranakan Etawah yang meliputi : weight, height slope, length index, width slope, depth index, foreleg length, balance dan cumulative index. Hasil penelitian menunjukkan bahwa rata-rata ukuran tubuh kambing jantan lebih besar dibandingkan dengan kambing betina. Dari perhitungan didapatkan nilai indeks morfologi kambing jantan adalah weight = 52726,34; Height slope = -1,88; Lenght index = 1,0165; Width slope = 0,9935; Depht index = 0,5003 dan Foreleg length = 27,24. Sedangkan indeks morfologi kambing betina adalah Weight = 47477,46; Height slope = -1,94; Lenght index = 1,0278; Width slope = 0,9645; Depht index = 0,4988 dan Foreleg lenght = 26,34. Kesimpulan dari penelitian ini adalah kambing Peranakan Etawah umur lepas sapih di Sentra Pembibitan Kambing di kecamatan Mestong kabupaten Muaro Jambi mempunyai indeks morfologi yang tidak berbeda jauh dengan kambing Peranakan Etawah yang ada di beberapa daerah di Indonesia.
kambing Peranakan Etawah, Indeks morfologi, umur lepas sapih.
ACE2 receptor, TRL-4 and SARS CoV-2: Do long acting opioids and opioid antagonists have potential for therapy?
Authors: Eagleton Marie , Stokes Siobhan , Fenton Fiona , Keenan Eamon 
Published: June 2021

Despite the advent of a vaccine, broadening the arsenal of drugs
effective in the treatment and prevention of COVID-19 disease remains
critical in the global effort to control the SARSCoV2 pandemic. Opioids
and opioid antagonists may have a role in treating and in the prevention
of this disease based on a number of observations: an unexpectedly low
incidence of COVID-19 has been observed in patients treated for opioid
dependency with long acting opioid drugs such as methadone; opioids bind
to the ACE2 transmembrane protein, a molecule that is widely considered
to be main host cell receptor for SARS CoV2 cell entry; opioids have
systemic immunomodulatory effects which may influence the response to
the virus; studies aimed at repurposing drugs for treatment of COVID-19
have identified that opioids have therapeutic potential and finally
there are ongoing trials of some of these drugs. The interaction of long
acting opioids or opioid antagonists with the ACE2 receptor and the
possible effects on TLR4 function in SARS CoV2 infection should be given
serious consideration when developing effective therapies.
Note an updated version of this preprint is under review with the
British Journal of Anaesthesia
Tendencias en los temas de los conceptos del Consejo Técnico de la Contaduría Pública como organismo normalizador técnico contable en Colombia
Authors: Munevar Moreno Rodolfo Antonio , Barón-Vivas Angie Viviana , Galindo-Rodríguez Yerly Andrea 
Published: June 2021

Las fuentes de información documental que emiten organismos normalizadores como el Consejo Técnico de la Contaduría Pública (CTCP) son documentos que aportan la evolución y el desarrollo de una institución y ameritan la revisión desde varios enfoques en la investigación. Un ejemplo es los conceptos que se originan a partir de las consultas realizadas por personas naturales y jurídicas tanto del sector privado como del sector público. El artículo tiene como propósito establecer las tendencias de temas de los conceptos emitidos y publicados por parte del CTCP en el período comprendido entre el año 1992 y el año 2018. En este avance se revisó el contenido de 6578 conceptos de 7191 que están publicados en la página del CTCP, estableciendo categorías relacionadas con los elementos de los estados financieros, el tipo de persona que realiza la consulta y el sector al que pertenece, utilizando la frecuencia, herramienta de la estadística descriptiva en los valores encontrados de las categorías definidas.

Como conclusión principal, se encuentra un punto de inflexión en el año 2009, que refiere a un aumento de emisión y publicación de conceptos por parte del CTCP dado posiblemente por el cambio de modelo contable en Colombia para ese mismo año. La contribución del artículo es un avance y propuesta para trabajar con fuentes documentales emitidas por instituciones públicas de la profesión, para este caso, con un enfoque descriptivo, pero que pueda abarcarse desde otros enfoques y metodologías de investigación.
Caminhos da crítica psicanalítica
Authors: Rios Cleusa 
Published: June 2021

Entrevista com Cleusa Rios Passos, professora titular da Faculdade de Filosofia Letras e Ciências Humanas da Universidade de São Paulo, que tem experiência na área de Letras, com ênfase em Teoria Literária, atuando principalmente nos seguintes temas: Guimarães Rosa, estudo das formas narrativas e confluências entre crítica literária e psicanálise. Desde 2005, coordena (com outro docente) o grupo de pesquisa "Crítica Literária e Psicanálise". Entrevista: Elisabeth CardosoEdição: Ana Paula Rodrigues da Silva, Thiago Fonseca (TV-PUC)Música: PIPA estúdio
PHYSICOCHEMICAL CHANGES OF DWARF BANANA (Musa acuminata) DURING VACUUM PACKAGING STORAGE
Authors: Marpaung David Septian Sumanto , Cahyani Dwi , Utari Ni Wayan Arya , Indriyani Anggia , Apriliani Resa 
Published: June 2021

Banana is tropical fruit contain health nutrition and fiber. Dwarf banana is one of type banana that well growth in Indonesia, particularly in Lampung Province. However, its economic value become exported commodities is limited by its short shelf life. In this study, the physicochemical changes were observed under vacuum packaging storage, in order to know the potency of vacuum packaging to prolong the shelf life of dwarf banana. The results showed that the vacuum packaging could reduce weight loss compare to other treatments. The maintenance of green color by vacuum packaging was also showed positive result. Furthermore, the dwarf banana under vacuum packaging storage was also showed lowest TSS, in other words, the dwarf maturity could be delayed. These results suggested the vacuum packaging could be used as potential packaging for dwarf banana Keywords: dwarf banana, vacuum packaging, postharvest, physicochemical properties