bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of Etching Mode and Composite Type on Bond Strength to Biodentine Using a “No-Wait” Universal Adhesive
Authors: Sarialioğlu Güngör Ayça , Uysal Betül Aycan 
Published: July 2021

The purpose of this study was to compare the shear bond strength (SBS) of four resin-based composite materials to a silicate-based cement using a “no-wait” universal bond with self-etch (SE) and etch-and-rinse (ER) modes. Acrylic blocks (n=80, 2mm depth, 5mm diameter central hole) were prepared. The holes were filled with BiodentineTM (BD) and divided into 4 main groups (n=20) according to the composite resin type used: Group FZ250: FiltekTM Z250 Universal Restorative (microhybrid), Group SDR: SDR Plus U Bulk Fill Flowable (low-viscosity bulk-fill), Group FBP: FiltekTM Bulk Fill Posterior (high-viscosity bulk-fill), Group EF: EsFlow™ Universal Flowable Composite (nanohybrid). A ‘no-wait’ universal bond (Clearfil Universal Bond Quick) was used for bonding application. Then each group was divided into 2 subgroups according to the etching mode applied (ER and SE). SBSs were measured and stereomicroscope was used to identify the failure modes. Selected samples of fracture surfaces were imaged by SEM. Tukey’s post-hoc and One-way ANOVA tests were used to analyze data. There were statistically significant differences among the composite groups (p<0.05). When SDR showed the highest bond strength values in SE (17.13 ± 2.98 MPa) mode, FBP showed the lowest bond strength values in ER (8.89 ± 2.46 MPa) mode. The mean SBS was not different between the SE and ER modes (p> 0.05). The SBS of BD to the resin composites depends on the composite type but application of the ‘no-wait’ universal bond in different etching modes is regardless of the SBS of BD to resin composites.
Ansiedad ante exámenes en universitarios: papel de engagement, inteligencia emocional y factores asociados con pruebas académicasAnsiedad ante exámenes en universitarios: papel de engagement, inteligencia emocional y factores asociados con pruebas académi
Authors: Ávila Toscano José Hernando , Rambal Rivaldo Laura , Oquendo Gonz´alez Kelly , Vargas Delgado Leonardo 
Published: July 2021

Introducción: La ansiedad ante los exámenes (AE) es común entre universitarios e implica manifestaciones cognitivas, motoras y fisiológicas de tensión y preocupación permanente ante la evaluación que puede afectar su desempeño académico.
Objetivo: Evaluar si el engagement, la inteligencia emocional y los factores asociados con la realización de pruebas académicas predicen las manifestaciones de AE en una muestra de 400 estudiantes universitarios.
Método: Mediante un diseño predictivo transversal se evaluó el engagement (Vigor, Dedicación, Absorción), la inteligencia emocional (Atención, Claridad, Reparación) y diversos factores relacionados con pruebas académicas, analizando su relación con las manifestaciones de AE, y se construyeron modelos de regresión categórica para definir el nivel predictivo de las variables.
Resultados: Se descartó la relación entre engagement y AE (p>.05) mientras que Claridad y Reparación se asociaron inversamente con las manifestaciones de AE, excepto las fisiológicas. Diferentes factores asociados con la realización de exámenes como control docente, temor a la evaluación y tipo de preguntas predicen las respuestas de ansiedad fisiológica (R2=.10, p<.01), motora (R2=.09, p<.01) y cognitiva (R2=.12, p<.01). La Claridad predice negativamente la ansiedad motora (β=-.131, p<.01).
Conclusiones: engagement académico y AE se registran como variables independientes una de la otra, entre tanto, la Claridad emocional regula débilmente la ansiedad motora. Factores cognitivos y situacionales al momento de realizar exámenes son relevantes en el desencadenamiento de la respuesta ansiosa.
Sistema Único de Assistência Social e Sistema de Justiça: explicitando problemáticas e orientações a psicólogas(os)
Authors: Jacinto Pablo Mateus dos Santos 
Published: July 2021

OBJETIVO: Este estudo trata-se de uma pesquisa documental que teve como objetivo apresentar uma análise crítica sobre a relação entre o Sistema Único de Assistência Social (SUAS) e o Sistema de Justiça brasileiro (SJ), com foco na atuação da psicologia. MÉTODOS: Foram analisados oito documentos oficiais adotados pelo Sistema Conselhos de Psicologia como referência para orientação. Utilizou-se o suporte do software MAXQDA para análise. Buscou-se responder a três questões: (a) Como ocorre a relação entre o SUAS e o SJ? (b) Quais os impactos das demandas do SJ na organização do trabalho da(o) psicóloga(o) no SUAS? (c) Quais posicionamentos e orientações o Sistema Conselhos de Psicologia adota perante essa questão? RESULTADOS: Constatou-se que a atuação da psicologia no SUAS em interface com o SJ envolve atividades previstas, como a execução de medidas socioeducativas e participação em audiências, mas frequentemente é acometida com demandas que extrapolam o planejamento, incluindo realização de perícias, avaliação e acompanhamento psicológico. Essas demandas foram associadas à precarização da política pública, sobrecarga de trabalho às equipes e conflitos éticos às(aos) psicólogas(os). Como posicionamentos, é apontado que a(o) psicóloga(o) pode recusar as solicitações, conforme justificativa de impedimento ético e técnico, porém deve-se priorizar acatá-las, executando-as conforme as especificidades do SUAS, não excedendo sua competência. CONCLUSÃO: Concluiu-se que a psicologia no SUAS pode contribuir com o SJ a partir de uma atuação intersetorial que respeite os objetivos da Assistência Social. O papel mediador das gestões é fundamental para elucidar atribuições e estabelecer fluxos profícuos de trabalho.
VİTİS VİNİFERA ÇEKİRDEK ÖZÜTÜ KULLANILARAK ALTIN NANOPARTİKÜLLERİN YEŞİL SENTEZİ VE KOLON KANSERİ (HT-29) HÜCRELERİNDE ANTİ- KANSER ÖZELLİKLERİNİN DEĞERLENDİRİLMESİ
Authors: GENÇ Selim , PEHLİVANOĞLU Suray , AYDIN ACAR Çiğdem , YEŞİLOT Şükriye 
Published: July 2021

Amaç
Son yıllarda metalik nanopartiküller antioksidan, antimikrobiyal
ve antikanser etkinlikleri ile nanotıp alanında
oldukça dikkat çekmektedir. Özellikle, kanser
tedavisinde farmakolojik etkinliği bilinen tıbbi bitkilerden
yeşil sentez metodu ile üretilen metal nanopartiküller
araştırmacıların ilgi odağı haline gelmiştir. Altın
nanopartiküller; kendilerine özgü kimyasal, fiziksel ve
nontoksik özellikleri ile ön plana çıkan metal nanopartiküllerden
biridir. Çalışmamızda, üzüm (Vitis vinifera)
çekirdeği sulu ekstraktı kullanılarak yeşil sentezi
gerçekleştirilen altın nanopartiküllerin (Vv-AuNP) tek
başına ve kemoterapötik bir ajan olan Gemsitabin ile
kombine kullanımının HT-29 kolon kanseri hücre hattı
üzerindeki sitotoksik, anti-proliferatif ve apoptotik etkilerinin
değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntem
Altın nanopartiküllerin yeşil sentezi, Vitis vinifera
sulu özütü kullanılarak gerçekleştirildi. Vv-AuNP’lerin
UV-görünür spektrofotometre, taramalı elektron
mikroskobu (SEM) ve Enerji Dağılımlı X-ışını Spektroskopisi
(EDX) gibi çeşitli analitik tekniklerle karakterizasyonu
yapıldı. Vv-AuNP'ler 0–80 μg/mL doz
aralığında tek başına ve Gemsitabin (100 μg/mL veya
200 μg/mL sabit doz) ile kombine olacak şekilde HT-
29 hücreleri ile 72 saat süresince muamele edildi.
Sitotoksik etkileri MTT testi ile değerlendirildi. Ayrıca,
HT-29 hücreleri üzerine Vv-AuNP’lerin artan dozlarda
(0-400μg/mL) tek başına ve Gemsitabin ile kombine
antiproliferatif etkileri ise BrdU testi ile belirlendi. Altın
nanopartiküllerin HT-29 hücreleri ile muamelesi sonrası
Kaspaz-3 aktivasyon düzeyi Western-blot yöntemi
ile analiz edildi.
Bulgular
MTT sonuçları değerlendirildiğinde Vv-AuNP’lerin 80
μg/mL doza kadar çıkıldığında HT-29 hücrelerinde
istenilen düzeyde sitotoksik etkiler göstermediği belirlendi.
BrdU hücre proliferasyon testi sonuçlarına dayalı
olarak, Vv-AuNP’lerin tek başına ve Gemsitabin
ile birlikte uygulamalarında IC50 değerleri sırasıyla
147.9 ve 39.43 μg/mL olarak belirlendi. Vv-AuNP dozlarına
bağlı kaspaz-3 aktivasyonunun kontrole kıyasla
arttığı, Gemsitabin ile kombine kullanımının bu etkiyi
güçlendirdiği gözlendi.
Sonuç
Sonuç olarak, yeşil sentezlenmiş AuNP’ler in vitro koşullarda
kolon kanseri hücreleri üzerinde anti-kanser
özellikler sergilemiştir. Bu çalışmanın sonuçları, Vv-AuNP'lerin
kolon kanseri tedavisi için potansiyel bir seçenek
olarak düşünülebileceğini göstermektedir.
ERKEN EVRE MEME KANSERLİ HASTALARDA BEDEN KİTLE İNDEKSİ DEĞİŞİMİ VE OBEZİTEYE BAĞLI SAĞLIK KOMPLİKASYONLARI
Authors: BİLGİNER Muhammet Cüneyt , KAVGACI Halil 
Published: July 2021

Amaç
Görüntüleme yöntemlerindeki gelişmeler ve multimodal
tedaviler, sağ kalan meme kanserli hasta sayısında
artışa neden olmuştur. Bu durum sağ kalımı
artıracak değiştirilebilir risk faktörlerinin araştırılması
gerektiğini düşündürmektedir. Biz bu çalışmada erken
evre meme kanserli hastaların takibinde ortaya çıkan
beden kitle indeksi (BKİ) değişikliklerini ve bu değişikliklerin
yol açabileceği obezite ile ilişkili sağlık sorunlarını
tespit etmeyi amaçladık.
Gereç ve Yöntem
Kliniğimize başvuran ‘‘Erken evre meme kanseri’’ tanısı
almış 142 hastanın BKİ (tanı anındaki), güncel
BKİ (tanita) ile karşılaştırılmıştır. BKİ’deki değişimlerle
obezite ilişkili sağlık sorunları arasındaki ilişki araştırılmıştır.
Bulgular
Hastaların ortalama yaşı 52,7 ± 1,1 (31-78) olup tamamı
kadın hasta idi. Tanı anında hastaların % 56,3
premenapozal, % 43,7 postmenapozal idi. Hastaların
tanıda BKİ ortalaması 27,9 ± 5,3 iken güncel BKİ
ortalaması 30,7 ± 5,7 olarak hesaplandı (p
AN APPROACH TO ACUTE APPENDICITIS CASES DURING PREGNANCY: A PUBLIC HOSPITAL PRACTICE
Authors: KIRMIZI Serdar 
Published: July 2021

Objective
Acute appendicitis is the most common non-obstetric
surgery performed during pregnancy. Physiological
and anatomical changes specific to pregnancy
complicate the diagnosis and treatment processes.
It has been seen in the literature that the studies on
this subject mostly reflect the experiences of tertiary
centers. The present study aimed to present the
perioperative experience of acute appendicitis cases
in pregnancy in a secondary care hospital.
Materials and Methods
The present study was carried out retrospectively
between January 2015 and November 2020 in a
secondary state hospital. Patients diagnosed with
acute appendicitis during pregnancy and whose
postoperative follow-ups and labors were carried out
in our hospital were included in the study.
Results
The median age of the patients was 24 years (18-
35), the median gestational week was 17 weeks (8-
32). The median leukocyte count was 11.6 x103 uL,
neutrophil count was 8.6 x103 uL, lymphocyte count
was 2 x103 uL, thrombocyte count was 271 x x103 uL,
C-reaktif protein was 4.5, neutrophil/ leukocyte ratio
was 4.3, thrombocyte/lymphocyte was ratio 120.8,
and the leukocyte /C-reaktif protein ratio was 0.7.
Spinal anesthesia was the most preferred method and
it was observed that open surgery was performed in
all patients. The median week of delivery was 38 (36-
40) and preterm labor was seen in only one patient.
It was observed that no additional maternal or fetal
complications developed.
Conclusion
Pregnant acute appendicitis patients can also be
successfully treated in secondary service hospitals on
the condition of a multidisciplinary approach.
LACUNAS NA FORMAÇÃO DOCENTE: ESTUDO COM PROFISSIONAIS DO ENSINO TÉCNICO DE ADMINISTRAÇÃO
Authors: Reinnaldi Maria Aldinete de Almeida , Giordani Annecy Tojeiro , Freitas Carlos Cesar Garcia 
Published: July 2021

A formação acadêmica do profissional em Administração engloba várias áreas do conhecimento, permitindo-lhe inúmeras opções de atuação no mercado de trabalho, inclusive na docência. Contudo, embora a prática docente seja de reconhecida importância, ainda é pouco valorizada, pois não é usualmente contemplada em inúmeros cursos de graduação no Brasil. Este estudo de natureza qualitativa e cuja análise dos dados se deu pela Análise Textual Discursiva se propôs a analisar lacunas formativas de dez professores de Administração do Ensino Profissional Técnico. Apesar da experiência prática em sala de aula e do domínio de conhecimentos específicos da área, os resultados apontam para deficiências relacionadas à formação pedagógica, ou seja, de caráter formativo, refletindo negativamente na atuação destes professores. Trata-se de lacunas referentes à sua concepção de ensino como, por exemplo: docência enquanto transmissão de conhecimentos, avaliação como forma de mensurar a aprendizagem do aluno, conhecimento do conteúdo como principal atributo de um bom professor, afora a parca mudança gerada a pela reflexão sobre a própria prática pedagógica. Foi identificada ainda, a ausência de conhecimentos relacionados aos fatores condicionantes da ação docente, definidos como um conjunto de atividades a serem desempenhadas pelo professor que lhe possibilita melhor atuação em sala de aula. As deficiências identificadas neste estudo, sugerem guardar estreita relação com o desempenho negativo destes professores considerando-se também, as dificuldades na docência por eles apontadas.
MODELO BRASILEIRO BASEADO NO MODELO AMERICANO DE PÓS-GRADUAÇÃO
Authors: Lima Netto Aristóteles Mesquita de , Carneiro Maria Esperança Fernandes 
Published: July 2021

Este artigo é produto do Decreto n.º 977/65 e do contexto histórico em que este documento foi elaborado. Os impactos que o referido decreto e as regulamentações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) competem à sistemática, regulação e avaliação de operacionalização das pós-graduações no Brasil e, consequentemente, das pesquisas. O objeto de estudo se manteve no recorte documental da pós-graduação stricto sensu nacional, observada como reprodução do modelo norte-americano, onde buscou-se evidenciar as aproximações e contradições entre eles. O método de investigação utilizado foi o materialismo histórico dialético na modalidade de pesquisa documental. A referida pesquisa encontra justificativa na necessidade de constituir um aporte teórico que subsidiará o percurso de escrita de tese do doutorado. Como referencial teórico este estudo buscou suporte nos seguintes autores: Freitag (1986), Chauí (2013), Verdike (2008), Santos (2003), Cury (2009) e Guaciarema (1972). Logo, os resultados revelaram que, tanto o Decreto n. º 19.850/31 quanto o Parecer CFE 977/65, representam os tentáculos do autoritarismo que visam ofertar títulos e atender o ideal neoliberal do capitalismo. Assim, constatou-se que o sistema de pós-graduação brasileiro tem sido orientado segundo os pressupostos da pós-graduação norte-americana que atende, prioritariamente, as demandas do mercado.
Survey-based evaluation of the awareness of pharmaceutical specialists on the pharmacotherapy of climacteric syndrome
Authors: Chernyavskaya M. A. , Narkevich I. A. 
Published: July 2021

Objective: to evaluate the awareness of pharmaceutical specialists on the pharmacotherapy of climacteric syndrome based on survey results.Material and methods. The authors analyzed 394 surveys of pharmaceutical specialists in Saint-Petersburg. The survey consisted of 13 questions, covered the personal characteristics of the participants (age, education, professional experience) and their knowledge about special medicines and food supplements to control climacteric symptoms, indications, and contraindications.Results. The results showed that pharmaceutical specialists saw the difference between combined oral contraceptives and menopausal hormone therapy, but they do not know about the protective cardiovascular effects of menopausal hormone therapy. Most specialists consider menopausal hormone therapy more effective than phytoestrogens, but they have no idea how it works. For most of them, there is hardly any difference between various classes of phytoestrogens. In their opinion, medical representatives and scientific conferences are the main providers of medical information.Conclusion. The analysis of the level of awareness of pharmaceutical specialists about the pharmacotherapy of menopausal syndrome based on the results of the survey revealed insufficient knowledge among pharmacy workers on a number of fundamental issues. Therefore, it is necessary to develop methodological recommendations on menopausal hormone therapy preparations and phytoestrogens-based drugs for pharmaceutical specialists who act as an important intermediate between a doctor and a patient.
Impact of disease information (Ebola and COVID-19) on the pharmaceutical sector in Russia and USA
Authors: Fedorova E. A. , Afanasyev D. O. , Sokolov A. V. , Lazarev M. P. 
Published: July 2021

Objective: identification of the relationship between the news coverage of global diseases and the dynamics of the return on shares of the pharmaceutical sector for Russia and the United States.Material and methods. The empirical base of the study includes more than 700 thousand tweets on Ebola and COVID-19 in Russian and English, news of the RBC news agency. The sentiment of the text was assessed on the basis of five English and four Russian-language dictionaries, the influence of fundamental and textual variables on the profitability of pharmaceutical companies' shares was carried out using the ARMAX-GARCH econometric model.Results. It has been proven that the dynamics of the stock index of pharmaceutical companies is explained by fundamental (economic) and sentimental factors. News of any epidemics negatively affects the pharmaceutical sector in the US and Russia, that is, there are no industries that benefit from this situation. Pandemic news affects US pharmaceutical companies more than Russian companies. The effect of news influence depends on the level of spread of the disease. News influences not only at the moment of their publication, but also after: there is a "delayed effect". Ebola news affects the American pharmaceutical market for 2 weeks, and the dynamics of the increase in influence can be traced. News on the COVID pandemic amplifies its impact during 1 week for the Russian pharmaceutical market and for 2 weeks for the US pharmaceutical companies. As for news sources, the elastic network has identified more significant variables based on publications from RBC; therefore, Internet publications generate more publicity, shaping a more significant overall sentiment in the markets.Conclusion. The models developed in the framework of the study and the economic conclusions obtained have not only theoretical, but also practical significance, and can also be used for further research in this area. It is possible to give recommendations on the practical use of dictionaries to assess the sentiment of the text. In our study, the elastic network method chose the Loughran–McDonald dictionary for evaluating economic texts in English and the EcSentiThemeLex dictionary (designed in R and Python programming environments). Avenues for further investigation may include analysis of other sources of information about the pandemic.
Relationship between thrombophilia status and short-term outcome in young adults with ischemic stroke
Authors: UZUNKÖPRÜ Cihat , BAŞKURT Esra , BEQİROSKİ Tea 
Published: July 2021

Purpose: Ischemic stroke is a serious health condition in patients with young adults. This study aims to determine thrombophilia polymorphisms in young patients with ischemic stroke and associations with other risk factors.
Materials and Methods: We evaluated 64 patients with ischemic stroke under 50 years old. Computerized Tomography Angiography, Holter Electrocardiography, Transthoracic Echocardiography, thrombophilia status, and Modifying Rankin Scale (MRS) in baseline and first month findings were recorded. We analysed the association between thrombophilia status and short-term outcome in young adults with ischemic stroke.
Results: 64 patients (38 male, 59.4%) were included in our study. The mean age of the patients were 42.486.73. The thrombophilia status showed that the most frequent polymorphism was MTHFRA1298T mutation (18.8% homozygous, 43.7% heterozygous). The second was MTHFRC677T and the third polymorphism was Factor 5 Leiden mutation, of 21.8% was homozygous and 34.4% was heterozygous mutation. 7.8% of the patients have atrial fibrillation, 17.2% of them have patent foramen ovale, and 7.8% have elevated pulmonary artery pressure (>30 mmHg). Thrombophilia status and PFO were not associated with IS in young adults.
Conclusion: Young patients with ischemic stroke have several thrombophilial polymorphism; however, we did not detect any association with IS. Young patients with ischemic stroke have also many classic risk factors which should be treated appropriately. Patent foramen ovale is another remarkable pathology and more researches are needed to realize its relation with ischemic stroke in young adults.
Effects of chronic illness adaptation on the healthy lifestyle behaviours of patients in internal services
Authors: ASLAN Hakime , ÇETKİN Tülay , DEMİR Rukiye 
Published: July 2021

Purpose: This descriptive study investigated the effects of chronic illness adaptation on the healthy lifestyle behaviours of patients in internal services.
Materials and Methods: The research was conducted with 104 inpatients at the Bingöl State Hospital. No sampling method was used in the study. A descriptive information form was utilised to record the patients’ sociodemographic characteristics. The Adaptation to Chronic Illness Scale (ACIS) and the Healthy Lifestyle Behavior Scale-II (HLBS-II) were used to collect the data on their adaptation and behaviour levels.
Results: The patients’ total mean ACIS score was 84.99±12.45, meaning that their adaptation to chronic illness was above average. Moreover, since their total mean HLBS-II score was 130.27±24.50, their adaptation to healthy lifestyle behaviours was moderate. The patients’ adaptation to chronic illness positively affected their healthy lifestyle behaviours (B=1.045), and this result was statistically significant.
Conclusion: Chronic illness adaptation positively influenced healthy lifestyle behaviours.
Assessment of suitability of pediatric index of mortality 2 score for monitoring the outcome of pediatric intensive care unit patients and associated risk factors of mortality in a tertiary care center in South India
Authors: Y. Sreekrishna , E. Adarsh , S. Lavanya T. 
Published: July 2021

Background: Pediatric index of mortality 2 (PIM 2) score is an illness severity and scoring systems used for predicting outcome of children admitted to PICU. The objective was to evaluate the usefulness of PIM 2 score in predicting mortality in our PICU, assess whether the model is calibrated to our case mix and to compare the observed and expected death rates by calculating standardised mortality ratio. Methods: It was a prospective observational study done in a tertiary care center from January 2019 to June 2020. Consecutive 120 patients admitted to PICU aged from 1 month to 18 years were enrolled in study. PIM 2 scoring was calculated for the data obtained within 1 hour of admission to PICU. The outcome was recorded as death or discharge. PIM 2 logit score is calculated using software.Results: PIM2 can discriminate between death and survival with area under curve (AUC) of 0.867 with 95% CI (0.729,0.980). PIM 2 predicted death rate was significant (p<0.001). The model is well calibrated with Hosmer- Lemeshow Goodness-of-fit test p=0.961 (p>0.05). The observed death rates are equal to predicted death rates and standardized mortality ratio (SMR) is equal to 1. Conclusions: PIM 2 score predicted mortality correlated well with observed mortality in PICU patients. The model is well calibrated for use in our set up and discriminate well between survivors and non-survivors.