bluuebunny/crossref_metadata_2025_split huggingface dataset:
Staphylococcus aureus with inducible clindamycin resistance and methicillin resistance in a tertiary hospital in Nepal
Authors: Thapa Devi , Pyakurel Susil , Thapa Sabita , Lamsal Suresh , Chaudhari Mahesh , Adhikari Nabaraj , Shrestha Dhiraj 
Published: December 2021

AbstractBackgroundStaphylococcus aureusis a global public health issue in both community and hospital settings. Management of methicillin-resistantS. aureus(MRSA) infections are tough owing to its resistance to many antibiotics. Macrolide-lincosamide-streptogramin B (MLSB) antibiotics are commonly used for the management of MRSA. This study was aimed to determine the occurrence of inducible clindamycin- and methicillin-resistantS. aureus at a tertiary care hospital in Kathmandu, Nepal.MethodsA total of 1027 clinical samples were processed following standard laboratory procedures and antibiotic susceptibility testing ofS. aureuswas performed by disc diffusion method. MRSA isolates were detected phenotypically using cefoxitin disc, and inducible clindamycin resistance was detected phenotypically using the D-zone test.ResultsOf 1027 samples, 321 (31.2%) were culture positive, of which 38 (11.8%) wereS. aureus. AllS. aureusisolates were susceptible to vancomycin, and 25 (67%) ofS. aureusisolates were multidrug-resistant. Similarly, 15 (39.5%) ofS. aureuswere MRSA and 14 (36.5%) were inducible clindamycin-resistant phenotypes.ConclusionInducible clindamycin and methicillin resistance were common inS. aureus. This emphasizes that the methicillin resistance test and the D-zone test should be incorporated into the routine antibiotic susceptibility testing in hospital settings.
An evaluation of the use of investigations in a nurse-led rapid access chest pain clinic
Authors: Kwok Chun Shing , Jackson Debbie , Bennett Sadie , Tafuro Jacopo , Large Adrian , Mallen Christian D , Smith Dot-Morgan , Duckett Simon 
Published: December 2021

Background/Aims Chest pain is a common symptom, but its presentation and cause varies widely, making diagnosis a challenge. This study describes the authors' experience of a nurse-led rapid access chest pain clinic, and associated use of investigation and patient outcomes. Methods A retrospective service evaluation of patients referred to a nurse-led rapid access chest pain clinic was performed. Routinely-recorded data on patient demographics, symptoms, comorbidities, medications, cardiology clinic attendances and investigations were collected. In addition, admissions to accident and emergency or inpatient, death, acute myocardial infarction and percutaneous coronary intervention within 1 year were obtained. Results A total of 279 patients were included in the evaluation between January and February 2019. Chest pain was present as a symptom in 92.8% of patients, while 37.6% of patients had shortness of breath. Only 16.8% had typical angina, while 34.4% had atypical angina. The majority (93.9%) had two or fewer cardiology clinic appointments, the most common imaging investigation used was computed tomography coronary angiogram (47.3%) and 8.2% had a stress echocardiogram or invasive angiogram. Approximately one in five patients had a hospital admission within 1 year. The mortality rate within 1 year was 1.4%, but were all non-cardiac causes. Only 3.6% underwent percutaneous coronary intervention and there was only one mortality. Conclusions This service evaluation shows that a nurse-led rapid access chest pain clinic can be safe, efficient and closely adhere to National Institute for Health and Care Excellence guidelines. Many patients do not require unnecessary and potentially harmful investigations and revascularisation rates are low.
The many becoming the unresolved one: Reconciling the fields of art, research and education through a/r/tography and collage
Authors: Garcia-Lazo Veronica 
Published: December 2021

Abstract
A study in three secondary schools in Aotearoa New Zealand explored students’ critical thinking and how that was articulated in visual arts education. The research was motivated by the influence of everyday visual experiences on young people’s lives and the national curriculum’s call for encouraging critical thinking in the context of the students’ cultural milieu. This inquiry entailed multiple methods that included policy analysis, focus group interviews with teachers, interviews with students, classroom observations, photographic documentation and researcher engagement with the art of collage. A/r/tography allowed for the reconciliation of art, research and education and the exploration of liminal spaces through a relational inquiry. The collage process provided insights into how art making can be used as a relational device between researcher and participants that evoked findings in innovative ways. The findings are presented as entanglements of meanings aimed to provoke the imagination and open conversations.
Avant-Garde As Method: Vkhutemas and the Pedagogy of Space, 1920–1930, Anna Bokov (2020)
Authors: Hudson-Miles Richard 
Published: December 2021

Review of: Avant-Garde As Method: Vkhutemas and the Pedagogy of Space, 1920–1930, Anna Bokov (2020)
Zurich: Park Books, 624 pp.,
ISBN 978-3-03860-134-0, h/bk, €58.00
Reseña / Economía Social y Solidaria. Mapeos, experiencias y políticas en Santa Fe y Reconquista
Authors: Mahieu Magalí Mercedes 
Published: December 2021

Economía Social y Solidaria. Mapeos, experiencias y políticas en Santa Fe y Reconquista reúne los resultados del proyecto de investigación “Mapeo, caracterización e interacción de los actores de la Economía Social y Solidaria en los municipios de Santa Fe, Reconquista y Rosario”. Como tal, este libro logra retratar tres sujetos propios del campo de estudio: cooperativas de trabajo, emprendimientos socioeconómicos y experiencias en territorios rurales en Santa Fe y Reconquista, dos localidades claves por la densidad que asumen dichas manifestaciones. Se abordan a través de espacios (Centro de Emprendedores de la Economía Social), organizaciones (Asociación de Emprendedores de Reconquista, Fundación Surcos), canales de comercialización (ferias francas, tiendas virtuales) y políticas que procuran servir de insumo para próximas investigaciones. Desde miradas comparativas y longitudinales, el método aplicado y el recorte teórico realizado son una expresión de los objetivos planteados. Es una obra que analiza integralmente el devenir de la otra economía.
Cognitive Development of Children Aged 4-7 Years During The Covid-19 Pandemic
Authors: Oktaviana Anita , Srianggita Indah 
Published: December 2021

Cognitive development is one aspect of child development that is very important to get intervention during the COVID-19 pandemic, Cognitive development is a development that is closely related to thinking skills, such as reasoning, memory, and the ability to solve practical problems. The cognitive mindset of early childhood is very much different from people who are teenagers and adults or even children who are in middle school and above. Elementary school age children have limitations in thinking about abstract things, cognitive development has a correlation with other developments and will have an impact especially on children's academic abilities. The purpose of this paper is to examine how the cognitive development of early childhood during the covid-19 pandemic and what strategies are carried out by parents in developing cognitive development of early childhood during the covid-19 pandemic? Based on the formulation of the problem above, the data analysis technique used in this study is an interactive model of data analysis in analysing the data carried out in three ways, namely data reduction activities, data presentation and also data conclusions. as well as parents. These results and discussions describe various issues related to cognitive development problems such as several barriers to children's activities and activities that have an impact on children's cognitive during the COVID-19 pandemic in Pangkalan Kuras District, Pelalawan Regency, Riau Province. In conclusion, this study aims to describe the cognitive development of early childhood during the COVID-19 pandemic and provide views regarding several activities that can be internalized to stimulate children's cognitive development.
Quantum chemistry study on the promoted reactivity of substituted cyclooctynes in bioorthogonal cycloaddition reactions
Authors: Hosseinnejad Tayebeh , Omrani-Pachin Marzieh 
Published: December 2021

AbstractIn the present research, we focus on the energetics and electronic aspects of enhanced reactivity in the regioselective bioorthogonal 1,3-dipolar cycloaddition reaction of various substituted cyclooctynes with methyl azide, applying quantum chemistry approaches. In this respect, we assessed the structural and energetic properties of regioisomeric products and their corresponded transition states and calculated the reaction electronic energy changes and energy barriers through the cycloaddition pathways. The obtained results revealed that the trifluoromethyl substitution and fluorination of cyclooctynes lead to improved reactivity, in conjunction with increased exothermicity and decreased activation energy values. On the other hand, quantum theory of atoms in molecules computations were performed on some key bond and ring critical points that demonstrated the stabilizing topological properties of electron density and its derivatives upon trifluoromethyl substitution and fluorination of propargylic carbon of cyclooctynes which can be regarded as the essential origin of enhanced reactivity.
Accurate estimation of modern power system harmonics using a novel LSA hybridized recursive least square technique
Authors: Bhoi Ashok , Mallick Ranjan Kumar , Panda Gayadhar , Nayak Pravati 
Published: December 2021

Abstract
This paper purposes a new type of hybrid technique depends on lightning search algorithm (LSA) and recursive least square (RLS) named as LSA-RLS to overcome the harmonic estimation issues in time varying modern power system signals buried with noises. LSA is based on a natural phenomenon of lightning. It consists of three types of projectiles: transition, space and lead projectiles. Transition projectiles create population, space projectiles do the exploration and the lead projectiles do the work of exploitation and find the optimal solution. The basic LSA algorithm is mixed with RLS algorithm in an adaptive way to estimate the states of the harmonic signals. Simulation and validation are made with real time data obtained from a converter fed D.C motor drive. The efficacy of the proposed algorithm is verified by comparing the simulation results of recently reported algorithms such as particle swarm optimization (PSO), differential evolution (DE), bacteria foraging optimization (BFO), gravity search algorithm hybridized recursive least square method (GSA-RLS). It is verified that proposed (LSA-RLS) technique is the best in terms of computational time, convergence, accuracy.
Review of fibreless optical communication technology: history, evolution, and emerging trends
Authors: Patle Nidhi , Raj Arockia Bazil , Joseph Chinchu , Sharma Nishant 
Published: December 2021

AbstractIn the present era of technology, it is quite fascinating to design a system capable of transmitting information from one end to another by using the optical spectrum. This system differs from optical fibre communication in terms of channel medium. Optical fibre technology uses the end-to-end physical connection via fibre. In contrast, Light-based wireless communication networks, also known as wireless optical communication (WOC) networks or fibreless optical communication networks, use light as a carrier and air as an unguided propagation media for transmission. Fibreless optical communication eliminates the need for Licensing and Buried Fibre Cables; also, its installation is relatively easy. This survey article describes the evolution of WOC technologies right from the old methods of communication to today’s deep-space optical satellite communication. This article briefly describes the WOC system working principle, categorization of wireless optical systems (based on the carrier frequency wavelength, distance covered, and application), different modulation techniques adopted for wireless optical communication, challenges associated with channel medium and channel modelling, performance analysis of WOC system, various application areas of WOC network, commercial developments in the field of WOC, and some other emerging trends associated with WOC.
CONSIDERATIONS ABOUT THE GEOMETRY OF THE SLOPE SPOIL PROFILATION WITH THE CPU TILLER WITH OLAC WORKING BODY
Authors: Cârdei P. , Co?a C. , Muraru V. 
Published: December 2021

The detachment and the transport of the sediments on the slope soil surface are caused by the water in the many cases, rain spray or dispersion or concentrated water rills. The development of these mechanical processes is also influenced by the factors which can be modified by the human intervention. In aim to disproof the slope soil erosion are necessary a lot of anti-erosion actions, for example the retention or conducted evacuation of the water. There is well known the location of the row crops oriented along of the level curve of the slope, but these actions are not enough for a good reducing of the erosion phenomena. For this reason is proposed another procedure, which made a soil profiling shapes. This procedure is applied using farm machinery which can profile the slope soil in the necessary shapes: billons between the crop rows and billons on the crop rows, simultaneous which other agricultural operations. In this paper is shown an analysis of the soil crisping (soil transversal shape) influence about the soil erosion. There are used erosion mathematical models based on USLE original model, which is included in the complex
software programs.
REGARDING THE USE OF THE LEXIN ECOLOGICAL, BIOGENETICAL HEATING TECHNOLOGY TYPE IN ROMANIA
Authors: Coman Mirela , Oros V. , F?l?us Bianca , Chinta O. , Achim M. 
Published: December 2021

The work presents the results obtained in the frame of an applicative research contract upon the use of ecological, biogenetic heating technology of Lexin kind, in consideration of using it in Romania in different domains of activity.
For the climatic conditions of our country, we proposed and perform a measurement program in the following fields: electric expenditure, climatic and micro-climatic, microbial loading of air, effects over plants, effects over pets and prolusions over general health and comfort status of human being. In this work we present the results obtained above the micro-climate measurements (temperature, relative air humidity, microbial loading of air), and effects over soil over from the room in which we used this type of heating system.
In the rely of these researches we are in right to affirm that the Lexin heating technology has benefic effects over preserving the homogeneity of the micro-climate conditions, over growth of plants and assures an easily growth of hygiene of medium in which this technology act.
A STUDY ON LIFE QUALITY IN THE RURAL AREA
Authors: Mateoc Sîrb Nicoleta , Mateoc T. , Seulean Victoria , Darvasi Doina , M?nescu Camelia 
Published: December 2021

Though in the developed economies there is a trend to remove differences between rural and urban from the points of view of accommodation, infrastructure development, and ensuring services necessary for the population, which has resulted in a loss of significance of the traditional perception of the rural area as underdeveloped area, in Romania there is still a major discrepancy between rural and urban which is not beneficial for the Romanian rural area.
Starting from these premises, we think that an analysis of the life quality in the Romanian rural area is opportune, taking into account that in the 12,946 villages of present Romania live over 45% (about 9.7 million inhabitants) of Romania’s population in conditions unbelievable for the 21st century and for the 3rd millennium when science and technology are very advanced worldwide in all the fields of activity; this is also the time in which globalisation as a phenomenon resulted in economic integration both regionally and worldwide as a result
of the large-scale promotion of information technologies (e.g. the Internet), of the removal of artificial barriers from the circulation of goods, services, capital, knowledge, and people.
MOLECULAR BIOLOGY TECHNIQUES INVOLVED IN ENVIRONMENTAL MONITORING
Authors: Odagiu Antonia , Oroian I. , Iederan C. , Burduhos P. , Pusta Dana , Balint Claudia 
Published: December 2021

A short review of the main molecular methods recently involved in monitoring
environmental pollution is the aim of our aper. The elimination of a wide range of pollutants and wastes from the
environment is an absolute requirement to promote a sustainable development of our society with low environmental impact. New methodological breakthroughs in sequencing, genomics, proteomics, bioinformatics and imaging are producing vast amounts of information. Functional genomic and metagenomic approaches will
increase our understanding of the relative importance of different pathways and regulatory networks to carbon
flux in particular environments and for particular compounds, and they will certainly accelerate the development of bioremediation technologies and biotransformation processes. Tools for in situ monitoring of environmental pollutants are destined for both aims providing early warning systems and conceiving more efficient and less expensive remediation treatments.
Влияние различных факторов на необменную сорбцию аминокислот анионообменниками
Authors: Хохлова Оксана Николаевна , Хохлов Владимир Юрьевич , Трошина Полина Владимировна , Быковская Алина Ивановна , Каширцева Елизавета Романовна 
Published: December 2021

С целью обзора ряда действующих факторов при необменной сорбции аминокислот ионообменниками исследовано влияние природы и ионной формы сорбента, сорбата и растворителя, условий проведения сорбции – температуры и диапазона концентраций на величину поглощения глицина и фенилаланина анионообменником АВ-17-2П, сверхсшитым сорбентом MN-150 из водных и спиртовых растворов при температурах 293 и 343 К в концентрационных диапазонах, ограниченных растворимостью аминокислот.
Установлено, что изменение ионной формы анионообменника АВ-17-2П с хлоридной на нитратную приводит к уменьшению количества поглощенного фенилаланина за счет изменения размерных и гидратационных характеристик противоиона, приводящих к ослаблению полярных взаимодействий в фазе сорбента при необменном закреплении аминокислот. Использование неводного растворителя, например, этилового спирта приводит к уменьшению растворимости аминокислот, а, следовательно, рабочего диапазона концентраций, уменьшению набухания анионообменника, что и обусловливает меньшее количество поглощаемой аминокислоты.
К существенному улучшению поглощения фенилаланина приводит использование сверхсшитого сорбента или повышение температуры. В первом случае усиливаются гидрофобные взаимодействия между ароматическим радикалом фенилаланина и матрицей сорбента. Во втором случае разнонаправленное действие температурного фактора на сорбат, сорбент и связи между ними в итоге приводит к увеличению сорбции за счет улучшения набухания ионообменника. Хорошая растворимость глицина позволяет исследовать поглощение этой аминокислоты в широком интервале концентраций. По виду полученной изотермы с учетом характеристик ионообменника установлено формирование в сорбенте последовательно первого и второго слоя вещества на сорбционных центрах «функциональная группа-противоион».
Использование ионообменной хроматографии на ДЭАЭ-целлюлозе для разделения изоферментов малатдегидрогеназы из гепатоцитов крыс в норме и при аллоксановом диабете
Authors: Селиванова Наталия Владимировна , Моисеенко Александр Владимирович , Бакарев Максим Юрьевич , Епринцев Александр Трофимович 
Published: December 2021

Целью данной работы являлось исследование особенностей функционирования мультифункционального фермента углеводного метаболизма – малатдегидрогеназы (МДГ) у крыс в норме, в условиях аллоксанового диабета и у животных с патологией, принимавших перорально спиртовой экстракт полыни горькой, а также выделение фермента с помощью ионообменной хроматографии. Индукцию экспериментального сахарного диабета осуществляли с помощью однократного внутрибрюшинного введения 5% раствора аллоксана самцам белых лабораторных крыс (Rattus norvegicus) линии Wistar. После появления признаков диабета всех крыс разделили на 3 группы: контрольные животные (аллоксан не вводился), группа «диабет» (животные с признаками диабета) и группа «диабет + экстракт полыни (ЭП)» (крысы с повышенным уровнем глюкозы в крови, принимавшие вместо воды спиртовой экстракт полыни).
Сравнение удельной активности МДГ из гепатоцитов печени крыс контрольной группы, подвергнутых аллоксановому диабету, и животных с патологией, принимавших экстракт полыни показывает, что в условиях индуцированного диабета скорость функционирования МДГ увеличивается, тогда как пероральное введение экстракта полыни снижало исследуемый показатель до нормальных значений. Для решения вопроса об активации при аллоксановом диабете тех или иных метаболических процессов, связанных с малатдегидрогеназной активностью проводили ее очистку.
Проведенные исследования показали, что по сравнению с контрольными животными, в гепатоцитах в которых присутствуют две изоформы МДГ2 и МДГ1 с удельной активностью 39.7 Е/мг белка и 48.0 Е/мг белка и степенью очистки 99.2 и 120.0, соответственно, у животных с экспериментальным диабетом появляется дополнительная изоформа МДГ3 с удельной активностью 38 Е/мг белка и степенью очистки 47.5. Для группы крыс, которым вводили перорально экстракт полыни, было характерно наличие двух изоформ МДГ с удельной активностью 72.08 и 60.5 Е/мг белка и степенью очистки 182.0 и 152.2, соответственно, что совпадало с тенденциями, характерными для изоферментов малатдегидрогеназы из контрольной группы животных. Таким образом, использование 4х-стадийной очистки позволило получить высокоочищенные препараты изоформ МДГ из печени крыс в условиях аллоксанового диабета. Увеличение активности и появление новой изоформы МДГ в печени крыс при диабете подтверждают возможность участия малатдегидрогеназной ферментной системы в адаптивной реакции организма при стрессовых условиях. Полученные результаты свидетельствуют, что экстракт полыни обладает гипогликемическим действием, проявляющимся в заметном снижении концентрации глюкозы в крови крыс при аллоксановом диабете, и блокировании образования дополнительной изоформы МДГ у животных с экспериментальным диабетом.