bluuebunny/crossref_metadata_2025_split huggingface dataset:
Towards a theory of communion‐in‐caring
Authors: Tuppal Cyruz P. , Vega Paolo D. , Tuppal Shanine Mae P. 
Published: December 2021

AbstractBackgroundWhen nursing practice assumes a fix‐it view model, it limits the growing capacity of practice. The theory of communion‐in‐caring emerged as a hopeful response to the call to offer a new vista. This theory unifies caring and the endless potential of human care.AimThe aim of the paper is to describe the theory of communion‐in‐caring grounded in the human science philosophical perspective. Generated from a focused review of scholarly literature from classical caring theories in nursing to contemporary theoretical viewpoints in nursing published within the last decade guided by a creative theory‐building process. This paper presents the theory of communion‐in‐caring with theoretical concepts and theoretical assumptions illuminating and supporting the contextual design and epistemological viewpoints of a caring‐based theory of nursing.FindingsCommunion‐in‐caring is defined as a deliberate and a momentary occurrence of a nursing‐caring encounter in which the nurse and person nursed, together, design and express unique practice processes toward affirming and celebrating being human in a unitary‐transformative world. The theory further illuminates the foundational acts (i.e. love, hope, faith and charity) emulated into the embodied processes of communion‐in‐caring (i.e., caring‐nurturing encounter, caring‐nurturing inquiry and caring‐nurturing capacity). Such cyclical, rhythmical and moving processes yield a nurtured caring environment with ethical standpoints, resonate the meaning‐essence of caring through participation‐in‐being and offer culturally congruent care.ConclusionThis theory also realises that the discipline is overly influenced by technological advancements, digitalisation of care, the medicalisation of practice and a mechanistic lens of care. Thus, this theory calls for moral enrichment towards an identity that embodies participation‐in‐being, seeing self‐in‐others and communion‐of‐being.
Burden of cystic fibrosis in children <12 years of age prior to the introduction of CFTR modulator therapies
Authors: Bresnick Kathryn , Arteaga-Solis Emilio , Millar Stefanie J , Laird Glen , LeCamus Cecile 
Published: December 2021

BackgroundCystic fibrosis (CF) is a genetic, multisystemic, progressive and life-shortening disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. Different genotypes have been linked to variations in disease progression among people with CF. The burden of illness (BOI) in children with CF is incompletely characterised, particularly as it relates toCFTRgenotypes prior to the availability of the first CFTR modulators. This retrospective, cross-sectional, descriptive study evaluated the BOI in US children with CF <12 years of age prior to the first approval of CFTR modulators.MethodsData from the US Cystic Fibrosis Foundation Patient Registry from 2011 were used to summarise key patient and disease characteristics using descriptive statistics, overall and grouped by age (0 to <2 years, 2 to <6 years and 6 to <12 years) and genotype (F508del/F508del,F508del/minimal function (MF), MF/MF, gating mutation on ≥1 allele, residual function mutation on ≥1 allele andR117Hon ≥1 allele) group.ResultsThe analysis included 9185 children. Among 6-year-olds to <12-year-olds, mean (SD) per cent predicted FEV1in 1 s was 92.6% (17.5%). Among all children <12 years of age, the mean (SD) all-cause hospitalisation and pulmonary exacerbation rates in 2011 were 0.4 (1.0) and 0.3 (0.8), respectively. Most (93.6%) had ≥1 positive lung microbiology culture. CF-related medication and nutritional supplementation use was common across all ages and genotypes. More than half (54.7%) had ≥1 CF-related complication. Evidence of disease burden was observed across the age and genotype groups studied.ConclusionsPrior to the approval of the first CFTR modulator therapies in children <12 years of age, CF was associated with substantial BOI from an early age—including respiratory infections, hospitalisations/pulmonary exacerbations, need for supplemental nutrition and pharmacological treatments—irrespective of genotype.
Prevalence of otomycosis in patients with cerumen impaction due to ear-phone usage during COVID-19
Authors: Suresh Sunethra , Suresh Suraj , Sivasamy Sudha 
Published: December 2021

Background: Otomycosis affects about 9% of patients with otitis externa. One of the predisposing factor is impacted cerumen. Earphone usage causes cerumen impaction. In the light of the recent COVID-19 pandemic, people are housebound due to prolonged lockdown. Hence people are more technology dependent as working from home and studying online has become the norm. Therefore, usage of earphones has proportionately increased, and the impacted cerumen cases have increased. Methods: This cross-sectional study aimed to analyze data from questionnaire to assess the prevalence of otomycosis among patients with impacted cerumen due to excessive earphone usage, establish associations between otomycosis and symptoms such as pain and hearing loss as well as the correlation between fungal growth and the long hours of earphones usage. The relationship between the age of participants and the usage of earphones during the pandemic was also explored. The data was collected from 100 individuals aged 14 to 51 years who sought treatment for symptomatic impacted wax at an ENT clinic in Malaysia. Results: The mean age of participants was 25.9 years. There was a 31% prevalence of otomycosis among these patients. Otalgia was present in 60% of patients with otomycosis (t value 2.94, coefficient 0.27). Approximately 37% of patients had a large air-bone gap indicating conductive hearing loss. There was an insignificant correlation between otomycosis and the longer hours of earphones usage (t value 1.51, coefficient 0.00015). No correlation was found between age of participants and the total hours of earphone usage (t value 0.63, coefficient 0.0012). Conclusion: This study offers initial evidence that earphone usage could be a predisposing factor in developing otomycosis. However, there was no evidence of longer hours of earphones usage increasing the chances of developing otomycosis. Additionally, symptoms like otalgia and conductive hearing loss could be present in both earwax impaction and otomycosis.
Théâtres utopiques de Roland Barthes
Authors: Cohen Judith 
Published: December 2021

L’œuvre de Roland Barthes oscille entre modernité et classicisme, pour autant, loin de considérer qu’il faille prendre parti et choisir sa propre conception de Roland Barthes, il s’agit de penser ce lien dans un rapport dynamique entre ces deux pôles au prisme de la notion d’utopie elle-même oscillant entre une forme de retour à un état antérieur et à la construction d’un programme idéal à venir. En effet, on peut penser avec Diana Knight dans son ouvrage Roland Barthes and Utopia : Space, Travel, Writting, que l’utopie est une thématique centrale au sein de l’œuvre de Roland Barthes ce qui rend son écriture ancrée dans sa propre modernité mais aussi dans la nôtre. L’utopie constitue un concept à deux jambes : l’une pratique et politique et l’autre théorique. À ce titre, on peut considérer que cette dualité propre à cette notion dès l’ouvrage de Thomas More construit en deux parties inséparables l’une de l’autre, explique en partie l’oscillation qui anime l’œuvre du critique français. On s’interrogera tout au long de cet article sur les liens que l’utopie noue entre le théâtre, la sexualité et l’amour au sein de l’œuvre de Roland Barthes en en suivant les « phases » tout en tentant d’en dégager des structures transversales et linéaires qui cherchent à remettre en question la dimension hétérogène et monolithique de ces « phases ».

utopie – théâtre – sexualité - amour.
Effect of Acute Exposure to Altitude on the Quality of Chest Compression‐Only Cardiopulmonary Resuscitation in Helicopter Emergency Medical Services Personnel: A Randomized, Controlled, Single‐Blind Crossover Trial
Authors: Vögele Anna , van Veelen Michiel Jan , Dal Cappello Tomas , Falla Marika , Nicoletto Giada , Dejaco Alexander , Palma Martin , Hüfner Katharina , Brugger Hermann , Strapazzon Giacomo 
Published: December 2021

Background
Helicopter emergency medical services personnel operating in mountainous terrain are frequently exposed to rapid ascents and provide cardiopulmonary resuscitation (CPR) in the field. The aim of the present trial was to investigate the quality of chest compression only (CCO)‐CPR after acute exposure to altitude under repeatable and standardized conditions.

Methods and Results

Forty‐eight helicopter emergency medical services personnel were divided into 12 groups of 4 participants; each group was assigned to perform 5 minutes of CCO‐CPR on manikins at 2 of 3 altitudes in a randomized controlled single‐blind crossover design (200, 3000, and 5000 m) in a hypobaric chamber. Physiological parameters were continuously monitored; participants rated their performance and effort on visual analog scales. Generalized estimating equations were performed for variables of CPR quality (depth, rate, recoil, and effective chest compressions) and effects of time, altitude, carryover, altitude sequence, sex, qualification, weight, preacclimatization, and interactions were analyzed. Our trial showed a time‐dependent decrease in chest compression depth (
P
=0.036) after 20 minutes at altitude; chest compression depth was below the recommended minimum of 50 mm after 60 to 90 seconds (49 [95% CI, 46–52] mm) of CCO‐CPR.

Conclusions
This trial showed a time‐dependent decrease in CCO‐CPR quality provided by helicopter emergency medical services personnel during acute exposure to altitude, which was not perceived by the providers. Our findings suggest a reevaluation of the CPR guidelines for providers practicing at altitudes of 3000 m and higher. Mechanical CPR devices could be of help in overcoming CCO‐CPR quality decrease in helicopter emergency medical services missions.

Registration

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT04138446.
Cardiac Arrest in Pigs With 48 hours of Post‐Resuscitation Care Induced by 2 Methods of Myocardial Infarction: A Methodological Description
Authors: Vammen Lauge , Munch Johannsen Cecilie , Magnussen Andreas , Povlsen Amalie , Riis Petersen Søren , Azizi Arezo , Løfgren Bo , Andersen Lars W. , Granfeldt Asger 
Published: December 2021

Background
Systematic reviews have disclosed a lack of clinically relevant cardiac arrest animal models. The aim of this study was to develop a cardiac arrest model in pigs encompassing relevant cardiac arrest characteristics and clinically relevant post‐resuscitation care.

Methods and Results
We used 2 methods of myocardial infarction in conjunction with cardiac arrest. One group (n=7) had a continuous coronary occlusion, while another group (n=11) underwent balloon‐deflation during arrest and resuscitation with re‐inflation after return of spontaneous circulation. A sham group was included (n=6). All groups underwent 48 hours of intensive care including 24 hours of targeted temperature management. Pigs underwent invasive hemodynamic monitoring. Left ventricular function was assessed by pressure‐volume measurements. The proportion of pigs with return of spontaneous circulation was 43% in the continuous infarction group and 64% in the deflation‐reinflation group. In the continuous infarction group 29% survived the entire protocol while 55% survived in the deflation‐reinflation group. Both cardiac arrest groups needed vasopressor and inotropic support and pressure‐volume measurements showed cardiac dysfunction. During rewarming, systemic vascular resistance decreased in both cardiac arrest groups. Median [25%;75%] troponin‐I 48 hours after return of spontaneous circulation, was 88 973 ng/L [53 124;99 740] in the continuous infarction group, 19 661 ng/L [10 871;23 209] in the deflation‐reinflation group, and 1973 ng/L [1117;1995] in the sham group.

Conclusions
This article describes a cardiac arrest pig model with myocardial infarction, targeted temperature management, and clinically relevant post‐cardiac arrest care. We demonstrate 2 methods of inducing myocardial ischemia with cardiac arrest resulting in post‐cardiac arrest organ injury including cardiac dysfunction and cerebral injury.
National Minorities in the Post-Revolutionary Era
Authors: Haertel Kateryna 
Published: December 2021

Abstract
This study looks into Ukraine’s minority politics after the Revolution of Dignity of 2014. It analyses the inclusivity of minority politics against three key parameters – institutional framework, dialogue mechanisms, and non-discriminatory policies. The research is conducted through an in-depth comparison analysis of minority politics of two post-revolutionary presidents – Petro Poroshenko (full term) and Volodymyr Zelenskyi (first two years). The conclusion is made that the political elites failed to drive an inclusive course towards ethno-linguistic minorities. The inclusivity along the three criteria has been provided impetus either on ad-hoc basis or not at all. On the level of policies, a regression can be observed. The underlying cause for the state not succeeding in achieving an inclusive minority course is that the two administrations had predominantly divergent motives for addressing this topic. As a result, the implementation of some inclusivity-oriented measures suffered and the minority-related discourse became highly politicized.
Place Matters
Authors: Hedegaard Liselotte 
Published: December 2021

Abstract
This article positions place within a phenomenological framework. Current philosophical inquiry shows little interest in place, yet academic disciplines concerned with spatial properties look to philosophy—and in particular phenomenology—to provide important contributions to overcome the limitations of quantitative methodologies, particularly with respect to sentiments of attachment to and identification with places. Seemingly, however, philosophy offers little support in this field. Place disappears from philosophical investigations during the Middle Ages and is replaced by considerations on space. Keeping the employment of phenomenological approaches in other academic disciplines in mind, this article sets out to explore traces of a re-emerging interest in place among twentieth-century phenomenologists. It proposes a phenomenological approach to place in which there is a shift from regarding place in terms of a where to understanding what a place is in human experience.
A Taxonomy of Environmentally Scaffolded Affectivity
Authors: Coninx Sabrina , Stephan Achim 
Published: December 2021

Abstract
In this paper, we argue that the concept of environmental scaffolding can contribute to a better understanding of our affective life and the complex manners in which it is shaped by environmental entities. In particular, the concept of environmental scaffolding offers a more comprehensive and less controversial framework than the notions of embeddedness and extendedness. We contribute to the literature on situated affectivity by embracing and systematizing the diversity of affective scaffolding. In doing so, we introduce several distinctions that provide classifications of different types of environmentally scaffolded affectivity. Furthermore, we differentiate eight dimensions (e.g., trust, individualization, or intent) that allow us to evaluate the quality and effectivity of scaffolds in particular applications. On that basis, we develop a taxonomy using paradigmatic examples of affective scaffolding. This taxonomy enriches the current debate by emphasizing distinctions that are often conflated and by identifying fields of application that are commonly overlooked.
Bodies-in-Relation: Fine-Tuning Group-Directed Empathy
Authors: Pawlett-Jackson Sarah 
Published: December 2021

Abstract
In this paper I analyze Alessandro Salice and Joona Taipale’s account of ‘group-directed empathy.’ I am highly sympathetic to Salice and Taipale’s account and intend this paper to be an endorsement of their project. However, I will argue that a more fine-grained account of group-directed empathy can be offered, and I seek to contribute to this discussion by outlining at least one way in which different types of group-directed empathy may be identified. I argue that while Salice and Taipale are right to claim that an account of group-directed empathy requires a corresponding account of ‘collective bodiliness,’ there is an important form of collective bodiliness that their account does not fully incorporate, namely embodied interaction between others. I argue that a closer look at the perceivability of interactions between others offers a richer and more complete account of how we can empathetically perceive shared emotions between groups of people.
Three-dimensional SPACE MR with CAIPIRINHA fourfold acceleration for assessing long head of biceps tendon
Authors: Liu Liangjin , Wu Gang 
Published: December 2021

Background Data regarding controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) T2-weighted sampling perfection with application optimized contrast evolution (SPACE) with fourfold acceleration factor for assessing long head of biceps tendon (LHBT) disorder is lacking. Purpose To investigate the feasibility of 3D CAIPIRINHA SPACE with fourfold acceleration in assessing LHBT disorder. Material and Methods A total of 42 consecutive patients underwent shoulder magnetic resonance (MR) examinations including CAIPIRINHA SPACE with fourfold acceleration, and non-CAIPIRINHA SPACE with twofold acceleration, and 2D fast spin echo (FSE). A subjective score of depiction of LHBT was given to 3D sequence according to a 4-point scale (0–3, “poor” to “excellent”). The Wilcoxon signed rank test was used to compare depiction scores between 3D sequences. Three statuses of LHBT were defined in the study: normal, tendonitis, and tear. McNemar’s test was used compare diagnostic accuracy. Results LHBT was better depicted with CAIPIRINHA SPACE versus non-CAIPIRINHA SPACE (2.1 ± 0.4 vs. 1.5 ± 0.4; P < 0.001). Inter-modality agreement between CAIPIRINHA SPACE and 2D FSE was almost perfect (kappa = 0.884 ± 0.064). The sensitivity and specificity in detecting LHBT disorder were 95% (20/21) and 95% (20/21), respectively, for CAIPIRINHA SPACE, and 71% (15/21) and 76% (16/21), respectively, for non-CAIPIRINHA SPACE ( P = 0.039). Conclusion Fourfold acceleration CAIPIRINHA is feasible in reducing the acquisition time of SPACE MR in the shoulder. 3D CAIPIRINHA SPACE with fourfold acceleration is highly accurate in detecting LHBT disorder.
Single-cell RNA sequencing reveals thatBMPR2mutation regulates right ventricular functionvia IDgenes
Authors: Du Mingxia , Jiang Haibin , Liu Hongxian , Zhao Xin , Zhou Yu , Zhou Fang , Piao Chunmei , Xu Guoqiang , Ma Feng , Wang Jianan , Perros Frederic , Morrell Nicholas W. , Gu Hong , Yang Jun 
Published: December 2021

BackgroundMutations in bone morphogenetic protein type II receptor (BMPR2) have been found in patients with congenital heart disease-associated pulmonary arterial hypertension (CHD-PAH). Our study aimed to clarify whether deficient BMPR2 signalling acts through downstream effectors, inhibitors of DNA-binding proteins (IDs) during heart development to contribute to the progress of PAH in CHD patients.MethodsTo confirm that IDs are downstream effectors of BMPR2 signalling in cardiac mesoderm progenitors (CMPs) and contribute to PAH, we generated cardiomyocyte-specificId 1/3knockout mice (Ids cDKO), and 12 out of 25 developed mild PAH with altered haemodynamic indices and pulmonary vascular remodelling. Moreover, we generatedID1andID3double-knockout (IDs KO) human embryonic stem cells that recapitulated the BMPR2 signalling deficiency of CHD-PAH induced pluripotent stem cells (iPSCs).ResultsCardiomyocytes differentiated from iPSCs derived from CHD-PAH patients with BMP receptor mutations exhibited dysfunctional cardiac differentiation and reduced calcium (Ca2+) transients, as evidenced by confocal microscopy experiments. Smad1/5 phosphorylation and ID1 and ID3 expression were reduced in CHD-PAH iPSCs and inBmpr2+/–rat right ventricles. Moreover, ultrasound revealed that 33% of Ids cDKO mice had detectable defects in their ventricular septum and pulmonary regurgitation. Cardiomyocytes isolated from mouse right ventricles also showed reduced Ca2+transients and shortened sarcomeres. Single-cell RNA sequencing analysis revealed impaired differentiation of CMPs and downregulated USP9X expression in IDs KO cells compared with wild-type cells.ConclusionWe found that BMPR2 signals through IDs and USP9X to regulate cardiac differentiation, and the loss of ID1 and ID3 expression contributes to cardiomyocyte dysfunction in CHD-PAH patients withBMPR2mutations.
Effects of COVID-19 pandemics on urinary metabolites in kidney stone patients: our kidney stone prevention clinic experience
Authors: Tavasoli Sanaz , Borumandnia Nasrin , Basiri Abbas , Taheri Maryam 
Published: December 2021

Abstract
Background
The dietary habits and lifestyle changes during the COVID-19 pandemic could affect the urinary risk factors in kidney stone formers. In this study, we investigated the effects of the COVID-19 pandemic on 24-h urine metabolites, as a surrogate for dietary intake, in patients with kidney stones, in Tehran, Iran.

Methods
We evaluated the medical records of all patients with urolithiasis who visited in our stone prevention clinic from the beginning of COVID-19 in Iran to 1 year later (Feb 2020–Feb 2021) and compared it with the patients’ medical records in the same period a year before COVID-19 (Feb 2019–Feb 2020).

Results
The results of our stone prevention clinic showed a decrease in the number of visits during COVID-19. Twenty-four-hour urine urea, sodium, and potassium were significantly lower, and 24-h urine magnesium was significantly higher during COVID-19. Higher 24-h urine oxalate was only shown in patients with the first-time visit, whereas lower 24-h urine uric acid and citrate were only shown in patients with the follow-up visits.

Conclusions
COVID-19 pandemics may change some of the dietary habits of the patients, including lower salt, protein, and fruit and vegetable intake. Although economic issues, restricted access, or sanitation issues may be the reason for the undesirable dietary changes, the importance of a quality diet should be discussed with all patients, as possible. Since the number of patients visited in the stone clinic was lower during COVID-19, virtual visits could be an excellent alternative to motivate patients with kidney stones.