bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regional Disparities in the European Union from the Perspective of Environmental Context Indicators
Authors: Belinska Stefaniia , Adamičková Izabela , Turčeková Natália , Buliková Miriam , Bielik Peter 
Published: April 2021

Abstract
The agricultural sector is one of the most important sectors of the countries’ economies and agricultural production has a huge socio-economic importance. In the current conditions of globalization and diversification of production, agriculture tries to achieve continuous development, realization of the potential, growth of the quantity and quality of the agricultural production, ensuring food security of the country. The quantitative and qualitative development of the agricultural sector takes place within a certain system, which is created under the influence of economic, social, and environmental factors based on innovations associated with transformation. These components of the current development of the agricultural sector are undergoing constant transformations, leading to the imbalances and the emergence of destructive processes within the complex system of the agricultural sector. Exploring regional disparities in terms of environmental and economic context indicators of CAP is strategically important for the stable rural and regional development of countries, increasing the competitiveness of agriculture, and sustainable and integrated development of regions. Based on the results of the calculations, we confirmed the effect of catching up between poorer and richer EU countries and identified the future trends in the occurrence and reduction of regional disparities.
Decoding the Entrepreneurial Capacity: the Case of Entrepreneurial Alertness
Authors: Stanić Marina 
Published: April 2021

Abstract
Over the last few decades, entrepreneurial alertness has established its place as one of the central concepts in entrepreneurship research. It implies one’s ability to identify opportunities that are overlooked by others and as such plays an important role in the process of opportunity discovery and creation. Entrepreneurial alertness is theoretically set as a multidimensional construct that comprises of scanning and searching for new information, associating and connecting seemingly unrelated pieces of information and making evaluations and judgments about potential opportunities. The purpose of this study is to explore the notion of entrepreneurial alertness among the youth in order to identify its relationship with metacognitive knowledge, metacognitive experience, perception of self-efficacy and entrepreneurial intention. The aim is to provide suggestions and guidelines to scholars and educators about the ways entrepreneurial alertness can be developed and enhanced through teaching methods as well as specific activities offered to students during their university study. The sample includes 206 business students on the undergraduate and graduate level majoring in seven different areas (financial management, marketing, general management, trade and logistics, business informatics, entrepreneurship and economic policy and regional development). Statistical methods applied in the data analysis included correlation analysis, factor analysis and analysis of variance (ANOVA). The results showed a statistically significant positive relationship between entrepreneurial alertness and all four preselected variables: metacognitive knowledge, metacognitive experience, perceived self-efficacy, and entrepreneurial intent. Various student activities outside the classroom contribute to higher levels of students’ entrepreneurial alertness. However, not all activities equally contributed to the development of students’ metacognitive knowledge. Students who volunteered in local non-profit organizations, did an internship in a company that operates in Croatia, participated in providing consulting services to small and medium businesses and took part in national case study competitions demonstrated higher levels of metacognitive knowledge. Finally, the paper provides suggestions to scholars, educators and policy makers in the field of entrepreneurship and education.
Well-Being and Residents’ Tourism Support – Mature Island Destination Perspective
Authors: Frleta Daniela Soldić , Badurina Jelena Đurkin , Dwyer Larry 
Published: April 2021

Abstract
Rapid tourism development accompanied by exponential increase in the number of tourists and visitors in destinations can disrupt the life of destination residents and negatively affect their support for (future) tourism development. On the other hand, residents economically dependent on tourism might have different attitudes toward tourism in comparison to those who are not economically involved in tourism. Several studies have found that economic dependence on tourism induces more positive perceptions of tourism impacts and higher degree of support than non-dependence. Another potential valuable predictor of tourism support could be residents’ subjective well-being, enhancing our understanding quality of life under the influence of tourism. The purpose of this study is to better understand local residents’ support for tourism development by exploring their well-being, involvement in tourism activities and perceived overall value of tourism development. In order to gain a specific perspective of island tourism destination, a sample of residents living on a small Adriatic island Vir (Croatia) was chosen. Vir is high seasonal and mature destination with annual number of visitors around 30 times bigger than the number of permanent residents. It was found that those residents who are directly or indirectly economically benefiting from tourism have significantly higher scores in personal and national well-being domains and also exhibit higher support towards future tourism development, than those who don’t experience economic benefits from tourism. Regression analysis of an island well-being perception index, revealed that tourism generates more benefits than costs and economical involvement in tourism positively affect residents’ tourism development support. On the other hand, demographic predictors (age, gender, education, income) and personal well-being index are not associated with tourism development support. The results provide important insights for researchers and practitioners on understanding residents’ perceptions of tourism in mature destinations and how those perceptions can be related both to subjective well-being and the level of involvement in tourism activities.
The study of the concept of medical literacy and approaches to its assessment
Authors: Volkova A. V. , Kovtun Ye. Yu. 
Published: April 2021

According to the Ministry of Health of Ukraine, almost 70% of the population self-medicates without seeking medical help. Therefore, the correct perception of medical and pharmaceutical information determines the correct use of drugs, their effectiveness and safety for the population.
Aim. To analyze global approaches to determining medical literacy and assessing its level in the world.
Materials and methods. The research materials were publications in scientific periodicals, monographs, materials of official websites of world organizations and databases, such as JMIR, PubMed, ISI Web of Science, Academic Search Premier and Allied Health Literature. During the study the methods of the content analysis, historical, system-analytical, generalization were used.
Results. The authors have reviewed the literature on the concept of “medical literacy” and approaches to its assessment. The chronological periods of formation of the concept of “medical literacy” have been generalized. The following tests have been identified as key tools for assessing medical literacy in most studies: TOFHLA, REALM, NVS, and HLS-EU-Q47. Based on the results of the content analysis of the existing approaches in assessing the level of medical literacy of the population, the main indicators proposed for evaluation have been generalized, and the advantages and disadvantages of these tests have been considered.
Conclusions. The analysis conducted has shown that a promising study is the development of universal and optimal tools for assessing the level of medical literacy, as well as the definition of the concept of “pharmaceutical literacy” with its components, the development of methods for assessing pharmaceutical literacy, the implementation and evaluation of practices to improve medical and pharmaceutical literacy.
Key words: the concept of “medical literacy” and “pharmaceutical literacy”, approaches of health literacy assessment.
The state regulation of the economic activities in domestic pharmacy: regulatory aspect
Authors: Zlahoda V. S. , Ivko T. I. , Germanyuk Т. А. , Bobrytska L. O. 
Published: April 2021

In modern working conditions, a pharmacist has insufficient knowledge of regulatory documents regulating the activities of the pharmaceutical industry. Thus, there is a need to provide informational assistance to the pharmacist by systematizing the current legal documents.
Aim. To scientifically generalize legal acts on the state regulation of the business entity in pharmacy in Ukraine.
Materials and methods. Regulatory legal acts regulating the process of the state regulation of the activity of an economic entity in pharmacy in Ukraine, and such methods as content analysis, generalization were used.
Results. As a result of the content-analysis it has been found that state supervision (control) of the pharmaceutical market of Ukraine is performed by the following state structures: the State Service of Ukraine for Medicines (Drugs) and Drug Control, the State Service of Ukraine for Food Safety and Consumer Protection, the State Fiscal Service, the State Labor Service of Ukraine, the State Emergencies Service of Ukraine.
Conclusions. When conducting the content-analysis it has been found that the legal documents regulating the process of pharmaceutical care provision in Ukraine are the Laws of Ukraine “On licensing of the economic activities”, “On consumer protection”, “On labor protection”. A graphic model of the state regulation of the business entity’s activity in Ukraine has been also created.
Key words: state regulation; business entity in pharmacy; regulatory legal acts; content-analysis.
Intention to use online meeting applications during Covid-19 pandemic: A Technology Acceptance Model perspective
Authors: Rini Gilang Puspita , Khasanah Imroatul 
Published: April 2021

This research aims to add to the repertoire on the knowledge of perceived risk effect on the intention to use online meeting applications during the COVID-19 pandemic. Data were obtained from 186 respondents using the questionnaire instrument, which had been tested, for validity and reliability. The obtained data were analyzed using the Structural Equation Model. Based on the data testing, it was found that all hypotheses in this research were accepted. Therefore, the intention to use online meeting applications was most affected by perceived ease of use comparing to perceived risk. The results showed that developingcompanies increased perceived ease of use, hence the technology is easily accepted by consumers.
A COMPREHENSIVE ASSESSMENT OF SEPTAGE MANAGEMENT IN BANTUL, YOGYAKARTA
Authors: Asmara Adelia Anju , Rahmawati Suphia , Yulianto Andik , Abay Margita Rahayu , Arlina Dilla , Wacano Dhandhun 
Published: April 2021

Aim: This study aims to assess the entire process of septage management comprising regulation, operational procedures, finance, community involvement, and water quality analysis to maximize the initial and hugest human fecal sludge treatment called Faecal Sludge Treatment Plant (IPLT) in Yogyakarta. Methodology and Results: The Modified EHRA (Environmental Health Risk Assessment) method was applied which focused only on wastewater treatment aspect. Several regulations including standard quality methods (SNI) were utilized and made a comparison between baseline rules and obtained results. Furthermore, quality assessment was accomplished by observation and interview. The results showed that the human sector needs to improve not only the amount of operators but also urgently put up protective personal equipment during the suction process. The dissemination of attractive information about sludge suction service done by PUPKP as a representation of the local government among the dwellers ought to upgrade a lot. Technologies employed which are carriage transportation and vacuum machine, are good enough. Contrarily, septage treatment plants require extra-effort to enhance it as most water quality parameters barely meet the standard quality. BOD, COD, ammonia, total coliform, oil and grease do not meet the third class of water quality (Government Regulation of Republic of Indonesia No. 82/2001). Subsequently, the effectiveness of each unit i.e. anaerobic tank and stabilization ponds are under 50% and the loading rate has a maximum capacity of 87.5m3/day, and 60m3/day minimum capacity. Conclusion, significance and impact of study: Therefore, almost all aspects of septage management in Bantul Yogyakarta are required to improve
Relationships between obstructive sleep apnea syndrome and cardiovascular risk factors
Authors: Evlampieva L. G. , Yaroslavskaya E. I. , Kharats V. E. 
Published: April 2021

The review analyzes data from domestic and foreign sources focusing on the current state of a common problem of obstructive sleep apnea syndrome. The article describes the main mechanisms of development and the possible relationships between the cardiovascular diseases, main risk factors in patients, and the sleep-related breathing disorder symptom-complex. The article provides the status update on the problem of continuous positive airway pressure (CPAP) therapy consisting in creating positive airway pressure ventilation and provides rationale for studying its effects on cardiovascular risk factors in various subgroups of comorbid patients.
Hereditary neuropathy with liability to pressure palsies: a case series report
Authors: Naudžiūnaitė S. , Bunevičiūtė R. , Burnytė B. 
Published: April 2021

Hereditary neuropathy with liability to pressure palsies (HNPP) is an autosomal dominant inherited peripheral nerve disorder characterized by recurrent, episodic local reversible peripheral nerve compression neuropathy that occurs spontaneously or after minor trauma.We describe demographic, clinical, and electrophysiological data of seven patients from six families (ages 17 to 74 years) diagnosed with HNPP. All patients had a genetically proven diagnosis of a deletion at 17p12 locus, which contains PMP22 gene. In five patients (71.4%), the first symptoms of HNPP (hypoesthesia, numbness, episodes of pain, and weakness) started in the second or third decade of life. One asymptomatic patient was diagnosed with HNPP based on a positive family history. Three patients (42.9%) reported that symptoms were caused by direct mechanical compression of the nerve. Three patients (42.9%) were found to have atrophy of the legs (calves or feet), hammer deformities of the toes, and pes cavus. Foot drop was observed in four patients (57.1%). In five patients, electroneurography showed signs of demyelinating type, in one – mixed (predominantly axonal).This study highlights the diversity of the clinical course of HNPP and the importance of early diagnosis including electrophysiological studies and genetic testing of copy number variation at 17p12 locus, which can prevent clinical manifestations of the disease and/or complications.
Comunicación e imaginario popular
Authors: Blanco Desiderio 
Published: April 2021

Tanto el discurso sociológico como el discurso político, educacional y moral sobre la comunicación social, insisten en señalar que el público receptor esta condicionado por los mensajes en su actitud receptiva. Es decir, que el cine, la televisión y la radio forman el gusto (=el mal gusto) del receptor.
Diverticular colon disease in patients with type 2 diabetes mellitus
Authors: Dorofeyev A. E. , Tkach S. M. , Derkach I. A. , Gdal V. A. , Dinya Yu. Z. , Chiwendu Beniah Ojum 
Published: April 2021

The aim of this study was to investigate the prevalence and features of the course of diverticular colon disease in patients with type 2 diabetes mellitus in the population of Ukrainian patients, as well as to analyze the effectiveness of the use of combination therapy using dietary fiber and rifaximin in these patients.
Materials and methods. We observed 140 patients with type 2 diabetes mellitus (DM 2). The age of the patients ranged from 39 to 69 years (mean age 53.1 ± 5.2 years), among the patients there were 84 women (60 %) and 56 men (40 %). The control group consisted of 67 patients with diverticular colon disease (DCD) without DM 2. Patients who complained of abdominal pain, flatulence, abnormal stool, abdominal discomfort underwent a hydrogen breath test with lactulose to establish bacterial overgrowth syndrome (SIBO) and colonoscopy. Patients with diabetes mellitus, in whom DCD was found and patients in the control group, in the presence of complaints, were prescribed rifaximin (Alpha normix) at a dose of 1200 mg per day for 14 days. After that, they were prescribed a diet with an increase in dietary fiber, and rifaximin at a dose of 800 mg per day for the first 7 days of each month. The patients were followed up for 6 months, patients were recommended to keep a diary of stool control, general condition and abdominal pain.
Results. Diverticular colon disease in patients with type 2 diabetes occurs with a frequency similar to that in the general population. DCD in DM 2 correlates with age and occurs mainly in patients over 55 years old, both in men and women. Most often, diverticulars are localized in the left half of the large bowel. Complaints of abdominal pain and stool disturbance in these patients are combined with SIBO, which is more intense in patients with DCD and DM 2.
Conclusions. It is advisable to use repeated courses of rifaximin 1200 mg per day for 2 weeks for the treatment of DCD in DM 2. When carrying out maintenance treatment, it may be advisable to increase the duration of rifaximin 800 mg per day from 7 to 10 first days of the month in combination with a diet enriched with dietary fiber.
Efficacy of Topical 5% 5-Fluorouracil and 0.05% Tretinoin and Electrosurgery in the Treatment of Plane Warts: A Randomized Controlled Comparative Trial
Authors: Singh Rashmi , Pandey Shyam Sundar 
Published: April 2021

Human papilloma virus (HPV) is capable of causing varieties of dermatological conditions differing in morphology, histopathology and site of occurrence. Plane wart is one of the morphological varients accounting for approximately one fifth of HPV lesions. Treatment of plane warts is difficult and recurrence quite common .The objective of our study is to compare the efficacy and safety of 5% 5 –fluorouracil (5 FU),0.5% tretinoin and electrosurgery in the treatment of plane wart. Seventy five patients 38 males and 37 females were included in this randomized controlled comparative trial .Patients were age and sex matched and divided into three groups, GROUP A : Patients treated with 5% 5-Fluorouracil ,GROUP B:Patients treated with 0.5% tretinoin and GROUP C : Patients treated with electrodessication .While topical treatments were applied once nightly for 4 weeks(5% 5-fluorouracil for four hours and tretinoin overnight), radiodessication was done at first visit only.Result and conclusion:While radiofrequency showed faster results , results were more consistent with least recurrence in 5-FU and fair recurrence with .05% tretinoin.
The Challenges of COVID-19 in Medical Education in Nepal
Authors: Paudel Vikash , Neupane Saraswoti 
Published: April 2021

The Coronavirus Disease-2019 (COVID-19) pandemic has caused an unparalleled disruption in all forms of scientific learning process including medical education. It has presented a challenge for scientists, educators, and students.Widespread interruptions to medical education, scientific discussions, conference, and seminars have also been seen at times of major conflicts and pandemics in the past as well, which resulted in major changes in medical curriculum. This editorial discusses the medical education and how COVID-19 has affected medical education in Nepal. Besides, it also explores the potential implications of COVID-19 for the future of medical education.
Steroid-induced Rosacea- A Study From a Tertiary Care Hospital of Eastern Nepal
Authors: Chaudhary Manoj , Agrawal Sudha 
Published: April 2021

Introduction: Topical corticosteroids (TC) are useful for treatment of various dermatological conditions in all age groups. Due to its cosmetic application TCs misuse is intertwined with fairness creams in our colour conscious society where people are obsessed with fair colour.

Aims and Objectives: To find the clinical presentations of steroid induced rosacea like-dermatitis on the face and to evaluate the purpose behind misusing TCs on the face.

Materials and methods: Descriptive prospective questionnaire-type case series study was approved by Institutional Ethical Committee of BPKIHS which involved 205 patients diagnosed as Steroid Induced Rosacea who consulted Dermatology OPD between March to June 2017.

Results: Among 205 patients enrolled, majority were from second to fourth decade (87.31%) of their life and maximum being females I.e. 91.2%. Around 97% of the study population were unaware of side effects of TCs. Most patients use Mometasone fuorate (58.04%) for melisma (88.29%). Friends acted as source of prescription (29.75%), followed by Pharmacist (24.88%) & Beauty centers (20%). Dermatologists prescribed TCs in only 6.34% cases. Sun exposure was identified as the triggering factor for steroid induced rosacea in 73.17% patients. Cheek was the commonest site involve in 92.19%, followed by forehead (65.36%), perioral area (46.83%), and chin (9.75%). Mixed type of lesions was the commonest lesion found in 52.20% patients, followed by diffuse facial erythema (36.09%), & telangiectasia (33.17%).

Conclusion: TCs misuse in the younger people for the sake of fairer skin with little or no knowledge about the adverse effects of this medication should be stopped.
Morphological improvement after multi-directional cranial distraction osteogenesis procedure for syndromic craniosynostosis
Authors: Kameda Masahiro , Tokuyama Eijiro , Senoo Takaya , Date Isao 
Published: April 2021

The multidirectional cranial distraction osteogenesis (MCDO) procedure, which uses an external distraction device, enables tailor-made distraction in an arbitrary direction, eliminating the disadvantage of unidirectional distraction with an internal distraction device. Multiple-suture synostosis cases for syndromic craniosynostosis patients are better indicated for this procedure. Here the authors describe seven cases in which the MCDO procedure was used to treat syndromic craniosynostosis. In each case, the MCDO procedure and postoperative distraction, with reference to midsagittal vector analysis of normal morphology in Japanese children, resulted in morphological improvement.
The video can be found here: https://vimeo.com/519006555
Single incision endoscopic strip craniectomy for sagittal craniosynostosis
Authors: Ahn Edward S. , Bhandarkar Archis R. 
Published: April 2021

The authors describe an endoscopic strip craniectomy through a single incision for the treatment of sagittal craniosynostosis in a young infant. The endoscopic strip craniectomy was first introduced with the use of two incisions on either end of the fused suture. This single-incision technique offers several advantages. There is a cosmetic advantage and a reduced risk of wound complications. This technique also allows for early control of emissary veins and an inside-out identification of the lambdoid sutures. Endoscopic visualization is optimized to reduce the risk of blood loss, especially because circulating blood volume is very limited in these young infants.
The video can be found here: https://vimeo.com/514366415