bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Lingkungan Belajar dan Disiplin Belajar Dengan Hasil Belajar Siswa Mata Pelajaran Instalasi Penerangan Listrik Program Keahlian Teknik Instalasi Tenaga Listrik Kelas XII SMK Karya Guna Jakarta
Authors: Maulidya Cahyani Sarah , Soeprijanto  , Faried Wadjdi  
Published: March 2021

ABSTRACT
This research was to aimed at finding out the relationships between environment of study and discipline of study towards student study results of electricity lighting installation subject an expertise program of electricity power installation technique class XII at SMK Karya Guna Jakarta. The population in this study were students of class XII TITL at SMK Karya Guna Jakarta as many as 31 people. Data collection methods for family environment variables and learning independence using questionnaire models with Likert Scale, while for the variable learning achievement of productive subjects using the method of documentation in the form of pure value Mid-Term Exams. The results showed that the hypothesis test with a significance level of 5% obtained rcount = 0,780 and value of rtable = 0,355 where rcount > rtable shows that there is a relationship between variables, then the value of Fcount = 21,75 and Ftable = 3.33 where Fcount > Ftable shows that there is a significance between variables and a determination value of 0,505 which shows the environment of study and discipline of study that have the same relationship to student study results.

ABSTRACT
Tujuan dari penelitian ini adalah untuk mengetahui hubungan lingkungan belajar dan disiplin belajar dengan hasil belajar siswa mata pelajaran instalasi penerangan listrik. Pada penelitian ini menggunakan metode ex post facto yang bersifat deskriptif korelatif dengan pendekatan kuantitatif. Populasi dalam penelitian ini adalah siswa/i kelas XII TITL di SMK Karya Guna Jakarta sebanyak 31 orang. Metode pengambilan data untuk variabel lingkungan belajar dan disiplin belajar menggunakan kuesioner model angket dengan Skala Likert, sedangkan untuk variabel hasil belajar mata pelajaran instalasi penerangan listrik menggunakan metode dokumentasi berupa nilai Ujian Tengah Semester. Hasil perhitungan menunjukkan bahwa uji hipotesis dengan taraf signifikan 5% di peroleh nilai rhitung = 0,780 dan nilai rtabel = 0,355 dimana rhitung > rtabel menunjukkan bahwa terdapat hubungan antar variabel, kemudian nilai Fhitung = 21,75 dan Ftabel = 3,33 dimana Fhitung > Ftabel menunjukkan bahwa terdapat signifikansi antar variabel dan nilai determinasi sebesar 0,505 yang menunjukkan bahwa lingkungan belajar dan disiplin belajar secara bersama-sama memiliki pengaruh sebesar 61% terhadap hasil belajar.
HUBUNGAN ANTARA KESADARAN KARIR (CAREER AWARENESS) DAN DISIPLIN DIRI DENGAN PRESTASI BELAJAR PADA MAHASISWA BIDIKMISI PROGRAM STUDI PENDIDIKAN TEKNIK ELEKTRO UNIVERSITAS NEGERI JAKARTA
Authors: Santi Selviana  , Soeprijanto  , Irzan Zakir  
Published: March 2021

Abstract
The purpose of this study was to determine the relationship between career awareness and self-discipline with the learning achievement of bidikmisi students in the Electrical Engineering Education Study Program at the State University of Jakarta. Hypothesis in this study is suspected that there is a positive and significant relationship between career awareness and self-discipline with the learning achievement of bidikmisi students in the Electrical Engineering Education Study Program, State University of Jakarta.This research is an ex-post facto research using a quantitative approach. The research subjects used were bidikmisi students of the Electrical Engineering Education study program at the State University of Jakarta with a sample of 29 students. Data collection techniques using questionnaires and documentation. The analysis technique used is the product moment correlation, hypothesis test and significance test.The calculation result shows that the hypothesis test with 5 % of significant level obtained = 0.495 > = 0.367 then the value of = 4.21 > = 3.37, if > , it can be concluded that there is a positive and significant relationship between the relationship between career awareness and self-discipline with Student Learning Achievement in Bidikmisi Student Study Program in Electrical Engineering Education,State University of Jakarta.
Abstrak
Tujuan penelitian ini adalah untuk mengetahui adanya hubungan antara kesadaran karir (career awareness) dan disiplin diri dengan prestasi belajar mahasiswa bidikmisi program studi Pendidikan Teknik Elektro Universitas Negeri Jakarta. Hipotesis dalam penelitian ini diduga bahwa terdapat hubungan yang positif dan signifikan antara kesadaran karir (career awareness) dan disiplin diri dengan prestasi belajar mahasiswa bidikmisi program studi Pendidikan Teknik Elektro Universitas Negeri Jakarta.
Penelitian ini merupakan penelitian ex-post facto menggunakan pendekatan kuantitatif. Subjek penelitian yang digunakan adalah mahasiswa bidikmisi program studi Pendidikan Teknik Elektro Universitas Negeri Jakarta dengan sampel sebanyak 29 mahasiswa. Teknik pengumpulan data menggunakan angket dan dokumentasi. Teknik analisis data yang digunakan adalah korelasi product moment, Uji Hipotesis dan uji signifikansi.
Hasil Penelitian menunjukkan bahwa uji hipotesis dengan taraf signifikan 5 % diperoleh nilai rhitung = 0,495 > rtabel = 0,367 , kemudian nilai Fhitung = 4,21 > Ftabel = 3,37. Jika rhitung > rtabel dan Fhitung > Ftabel maka dapat disimpulkan bahwa terdapat hubungan yang positif dan signifikan antara Hubungan antara Kesadaran karir (career awareness) dan Disiplin Diri dengan Prestasi Belajar Mahasiswa Bidikmisi Program studi Pendidikan Teknik Elektro Universitas negeri Jakarta.
Prevalence and Risk Factors of Toxoplasma Gondii and Leishmania Spp. Infections in Apparently Healthy Dogs in West Shewa Zone, Oromia, Ethiopia
Authors: Gebremedhin Endrias Zewdu , Serba Edilu Jorga , Tola Getachew Kebebew , Endalew Solomon Shiferaw , Marami Lencho Megersa , Melkamsew Asaminew Tesfaye , Vincenzo Di Marco , Vitale Maria 
Published: March 2021

Abstract
Background

In urban settings, the presence of a high density of human population and contacts with domestic and or stray animals such as dogs and cats can be risk factors for the transmission of zoonotic diseases. Toxoplasma gondii (T. gondii) and Leishmania spp. are zoonotic protozoon parasites with great health burdens worldwide.
Methods

A cross-sectional study was used to investigate the antibody prevalence and risk factors of T. gondii and Leishmania spp. infections in 385 randomly selected dogs of Ambo, Bako, and Gojo towns of West Shewa zone, Oromia regional state, Ethiopia. A questionnaire survey was administered to households to collect data on potential risk factors. Dog sera samples were assayed for T. gondii IgG antibodies by using the direct agglutination test while Leishmania spp. specific antibodies were tested using an indirect enzyme-linked immunosorbent assay (ELISA) kit. Logistic regression was used for data analysis.
Results

An overall 82.86% (95% CI): 78.71–86.49%) and 92.47% (95% CI: 89.36–94.90%) seroprevalence of T. gondii and Leishmania spp. was found respectively. Seropositivity for both T. gondii and Leishmania spp was found in 82.58% of the dogs. None of the investigated factors were associated with Leishmania spp. seropositivity (p > 0.05). Furthermore, altitude, sex, breed, housing, feeding, educational level of head of the household, and the living area of dogs were not significantly associated with T. gondii seropositivity (p > 0.05). The seroprevalence of T. gondii was significantly different between the study towns (p = 0.003). The risk of T. gondii infection was 2.71 times higher in adult dogs than juvenile dogs (p = 0.043). Dogs kept simultaneously with other domestic animals had increased odds of T. gondii seropositivity as compared to those with no other domestic animals (Adjusted Odds ratio: 1.96, p = 0.021).
Conclusions

The high seropositivity and the concomitant presence of antibodies of T. gondii and Leishmania spp. in dogs suggest the widespread nature of these parasites in the environment and the high potential of transmission to other animals and humans. Further epidemiological studies, isolation and molecular characterization of the parasites, and educational campaigns are suggested.
Hemp seed oil can accelerate the virgin mice mature and balance sex hormones, modulates organ atrophy, and restores in ovariectomized mice through upregulates ER𝛼 and ER𝛽 expressions
Authors: Wu Su Hui , Wang lin lin , Li han bing , Li gen lin , Guo chen yang , Zhang Juan 
Published: March 2021

Abstract
BackgroundHemp seed, the dried fruit of Cannabis sativa L., has been well documented as a folk source of food due to its nutritional and functional value. The aim of this study was to evaluate the estrogen-like effect of hemp seed oil (HSO) and analyze its action on the development of ovary and uterus of mice, concentration of sex hormones, endometrial thickness, and ER𝛼 and ER𝛽 expression. MethodsIn the present work, virgin and ovariectomized kunming mice were subject to treat with HSO. Gonad morphous was detected by Hematoxylin-Eosin (HE) staining, serum levels of E2, FSH and LH was determined used ELISA to evaluate the function of hypothalamic-pituitary-ovarian axis, and ERα and ERβ immunohistochemistry were used to evaluate gonad function. ResultsThe results showed that HSO can promote the vaginal opening time of virgin mice. There was significant increase in the gonad coefficient. Moreover, the endometrial thickness, number of primary follicles, secondary follicles and mature follicles were significantly increased, the uterus and ovary were well developed, the ERα and ERβ positive cells and intensity were increased in the virgin mouse ovary. The level of serum E2 was significantly increased, and the levels of FSH and LH were decreased. HSO could obviously relieve the endocrine disorders, modulate organ atrophy, and restore ER𝛼 and ER𝛽 expression in the ovariectomized mice model. ConclusionsHemp seed oil can accelerate the virgin mice mature and balance sex hormones, modulates organ atrophy, and restores in ovariectomized mice through upregulates ER𝛼 and ER𝛽 expressions. This study demonstrated that HSO activity is mediated through estrogenic components, and provided evidence for HSO treatment for post-menopausal symptoms.
Spontaneous ruptured of splenic artery aneurysm: Another reason for fatal syncope and shock(Case report and literature review)
Authors: Yuan Feng , He Liudang , Yao Zhengbin , Long Yong , Xu Shugen 
Published: March 2021

Abstract
Background: Splenic artery aneurysm(SAA) is a rare condition, however, it is one of the most common intra-abdominal aneurysm. In the emergency department, due to an uncommon cause of shock and syncope in SAA , it poses a great diagnostic challenge for emergency physicians. Here we reported the case of a spontaneous ruptured of splenic artery aneurysm, which was detected by point-of-care ultrasound (POCUS), in a 47-year-old man with syncope and shock. The diagnosis was further confirmed with a computed tomography scan and surgery.Case presentation: A 47-year-old man presented to the emergency department(ED) for syncope and shock. As he had unstable hemodynamic so we gave him fluid resuscitation and point-of-care ultrasound (POCUS), free intraperitoneal fluid was identified on ultrasound, then a diagnostic abdominal paracentesis was performed and hemorrhagic ascites were identified. The rare but life-threatening diagnosis of spontaneous ruptured of splenic artery aneurysm was confirmed by contrast-enhanced CT and surgery.Conclusions: Spontaneous splenic artery aneurysm ruptured is a rare fatal condition needs immediately diagnosis and management to achieve a favorable outcome. Though there is no risk factors, emergency physicians should considered SAA in the differential diagnosis of sudden collapse. As an emergency physicians, it is very important to be master first aid skills such as POCUS.
DHHC21 Deficiency Attenuates Renal Dysfunction During Septic Injury
Authors: Yang Xiaoyuan , Zheng Ethan , Ma Yonggang , Chatterjee Victor , Villalba Nuria , Breslin Jerome W. , Liu Ruisheng , Yuan Sarah Y. 
Published: March 2021

Abstract
Renal dysfunction is one of the most common complications of septic injury. One critical contributor to septic injury-induced renal dysfunction is renal vascular dysfunction. Protein palmitoylation serves as a novel regulator of vascular function. Here, we examined whether palmitoyl acyltransferase (PAT)-DHHC21 contributes to septic injury-induced renal dysfunction through regulating renal hemodynamics. Multispectral optoacoustic imaging showed that cecal ligation and puncture (CLP)-induced septic injury caused impaired renal excretion, which was improved in DHHC21 functional deficient (Zdhhc21dep/dep) mice. DHHC21 deficiency attenuated CLP-induced renal pathology, characterized by tissue structural damage and circulating injury markers. Importantly, DHHC21 loss-of-function led to better-preserved renal perfusion and oxygen saturation after CLP. The CLP-caused reduction in renal blood flow was also ameliorated in Zdhhc21dep/dep mice. Next, CLP promoted the palmitoylation of vascular α1-adrenergic receptor (α1AR) and the activation of its downstream effector ERK, which were blunted in Zdhhc21dep/dep mice. Vasoreactivity analysis revealed that renal arteries from Zdhhc21dep/dep mice displayed reduced constriction response to α1AR agonist phenylephrine compared to those from wild-type mice. Consistently, inhibiting PATs with 2-bromopalmitate caused a blunted vasoconstriction response to phenylephrine in small arteries isolated from human kidneys. Therefore, DHHC21 contributes to impaired renal perfusion and function during septic injury via promoting α1AR palmitoylation-associated vasoconstriction.
Vitamin D Supplementation and Body Composition Changes in Collegiate Basketball Players A 12-Week Randomized Control Trial
Authors: Hew-Butler Tamara , Aprik Carrie , Byrd Brigid , Sauborin Jordan , VanSumeren Matthew , Smith-Hale Valerie , Blow Andrew 
Published: March 2021

Abstract
BackgroundVitamin D promotes bone and muscle growth in non-athletes, suggesting supplementation may be ergogenic in athletes. Our primary aim was to determine if modest Vitamin D supplementation augments favorable body composition changes (increased bone and lean mass, decreased fat mass) and performance in collegiate basketball players following 12-weeks of standardized training. MethodsMembers of a men’s and women’s NCAA D1 Basketball team were recruited. Volunteers were randomized to receive either a weekly 4000IU Vitamin D3 supplement (D3) or placebo (P) over 12-weeks of standardized pre-season strength training. Pre- and Post-measurements included: 1) serum 25-hydroxy vitamin D (25-OH-D); 2) body composition variables (total body lean, fat and bone mass) using a dual energy x-ray absorptiometry (DXA) scan; and 3) vertical jump test to assess peak power output. Dietary intake was assessed using Food Frequency questionnaires. Main outcome measures included changes (∆: post- minus pre-intervention) in serum 25-OH-vitamin, body composition, and performance.ResultsEighteen of 23 players completed the trial (8 females/10 males). Eight received the placebo (20±1years; 3 females) while ten received Vitamin D3 (20±2years; 5 females). Weekly Vitamin D3 supplementation induced non-significant increases (∆) in serum 25-OH-vitamin D (2.6±7.2 vs. -3.5±5.3ng/mL;p=0.06), total body bone mineral content (BMC) (73.1±62.5 vs. 84.1±46.5g;p=0.68), and total body lean mass (2803.9±1655.4 vs. 4474.5±11389.8g; p=0.03), plus a non-significant change in body fat (-0.5±0.8 vs. -1.1±1.2%; p=0.19) (Vitamin D3 vs. placebo supplementation groups, respectively). Pre 25-OH-D correlated with both Δ total fat mass (g) (r=0.65;p=0.003) and Δ total body fat% (r=0.56;p=0.02). No differences noted in peak power output ∆ between the D3 vs. P group(-127.4±335.4 vs. 50.9±9W;NS). Participants in the D3 group ingested significantly fewer total calories (-526.2±583.9 vs. -10.0±400kcals;p=0.02) and sodium (-991.4±986.1 vs. 174.1±573.6mg;p=0.02) than participants in the P group.ConclusionsModest (~517IU/day) vitamin D3 supplementation did not enhance favorable changes in total body composition or performance, over 3-months of training, in collegiate basketball players. We alternatively exposed the potential role of sodium on bone metabolism. More practically speaking, weight training provides a robust training stimulus for bone and lean mass accrual, which likely predominates over isolated supplement use with adequate dietary intakes.Trial registration: ISRCTN, ISRCTN14155111. Registered 3 November 2020 - Retrospectively registered, http://www.isrctn.com/ISRCTN14155111
A Bibliometric Analysis and Visualization of Current Research Trends in the Treatment of Plantar Fasciitis
Authors: Xu Xiaoyan , Sun Yijun , Zheng Jiale , Xu Chongqing , Ma Qingshan , Ding Xing , Yin Mengchen , Ma Junming 
Published: March 2021

Abstract
Plantar fasciitis has become a common health problem. Both in theory and in therapy of plantar fasciitis has progressed rapidly in the past few decades, but there were no bibliometric studies regarding plantar fasciitis. This study aimed to illustrate the overall knowledge structure and development trends of plantar fasciitis. The research datasets were collected from the Web of Science, limited to articles published before Dec 16, 2020. VOS viewer and Citespace software were provided to analyze the data and generate visualization knowledge maps, including annual trends of publications, distribution, h-Index status, citations status, co-authorship status and research hotspots. 1429 publications met the requirement. The number of publications showed an upward trend with a stable rise in recent years. In the fields of plantar fasciitis, the United States published most papers (493, 34.50%), both total citations (13268) and h-index (65) ranked first of all the countries; the most productive institution was La Trobe University (30); Foot & Ankle International (122) published the most papers. Growth factor, wave therapy, corticosteroid, foot function index and physical therapy were the research hotspots in the recent years. Indeed, this study provides great insights to the growth and development of plantar fasciitis. Moreover, it will contribute to the growth of the international frontier of plantar fasciitis. Level of Evidence II.
Early Definitive Internal Fixation for Infected Nonunion of the Lower Limb
Authors: Yoon Yong-Cheol , Oh Chang-Wug , Cho Jae-Woo , Oh Jong-Keon 
Published: March 2021

Abstract
Management of an infected nonunion of the long bones is quite difficult and challenging. A staged procedure comprising of radical debridement followed by definitive internal fixation is favored. However, no standard treatment has been established for determining the appropriate waiting period between the initial debridement and the definitive internal fixation. We proposed a management incorporating early definitive internal fixation for infected nonunion of the lower limb. Thirty-four patients (28 men, 6 women) with infected nonunion of the tibia or femur were included. Initial infected bone resection and radical debridement were performed for each patient in accordance with the preoperative plans. Definitive surgery was performed 2–3 weeks after the resection (4 weeks after flap surgery was required), and the third surgery was performed to fill the bone defect through bone grafting or transport (three-stage surgery). Radiological and functional results were investigated in accordance with the Association for the Study and Application of the Method of Ilizarov criteria. Bone union was achieved in 100% of the patients, and treatment was conducted as planned preoperatively in 28 patients (28/34, 82.4%). The mean interval between the primary debridement and the secondary definitive fixation was 2.76 weeks (range, 2–4 weeks). The radiological and functional outcomes were good or better in 32 and 31 cases, respectively. In conclusions, Early definitive surgery can be performed to treat infected nonunion by thorough planning and implementation of radical resection, active response to infection, restoring defected bones, and soft tissue healing through a systemic approach.
Somatic whole genome dynamics of precancer in Barrett’s Esophagus
Authors: Paulson Thomas , Galipeau Patricia , Oman Kenji , Sanchez Carissa , Kuhner Mary , Smith Lucian , Hadi Kevin , Shah Minita , Arora Kanika , Shelton Jennifer , Corvelo Andre , Johnson Molly , Emde Anne-Kathrin , Maley Carlo , Yao Xiaotong , Sanghvi Rashesh , Venturini Elisa , Hubert Benjamin , Imielinski Marcin , Robine Nicolas , Reid Brian , Li Xiaohong 
Published: March 2021

Abstract
While the genomes of normal tissues undergo dynamic changes over time, little is understood about the temporal-spatial dynamics of genomes in premalignant tissues that progress to cancer compared to those that remain cancer-free. Here we use whole genome sequencing to contrast genomic alterations in 427 longitudinal samples from 40 patients with stable Barrett’s esophagus compared to 40 Barrett’s patients who progressed to esophageal adenocarcinoma (ESAD). We show the same somatic mutational processes were active in Barrett’s tissue regardless of outcome, with high levels of mutation, ESAD gene and focal chromosomal alterations, and similar mutational signatures. The critical distinction between stable Barrett’s versus those who progress to cancer is acquisition and expansion of TP53-/- cell populations having complex structural variants and high-level amplifications, which were detectable up to six years prior to a cancer diagnosis. These findings reveal the timing of common somatic genome dynamics in stable Barrett’s esophagus and define key genomic features specific to progression to esophageal adenocarcinoma, both of which are critical for cancer prevention and early detection strategies.
Analysis of Genetic Variation in Circadian Rhythm Genes and Risk of Ovarian Cancer.
Authors: Verma Sonali , Chander Gresh , Bhat Amrita , Bhat Gh.Rasool , Bakshi Divya , Sharma Bhanu , Rana Himanshu , Suri Jyotsna , Wakhloo Ajay , Singh Supinder , Bhat Audesh , Qadri Raies Ahmad , Shah Ruchi , Kumar Rakesh 
Published: March 2021

Abstract
BackgroundDisruption in biological clock due to genetic variations is associated with increased occurrence of cancers such as breast, ovary, prostate, gastrointestinal and hematological malignancies. Circadian rhythm genes regulate the process of ovulation in the ovaries and are highly expressed in ovarian tumors; whereas disturbance in the circadian rhythm pathway is significantly associated with causative risk factors (i.e. endometriosis, PCOS, etc.) of ovarian cancer. Nevertheless, very few studies have been conducted till date where candidate SNPs of circadian rhythm genes proved as the main prognosticators of ovarian cancer risk and intrusiveness. The main purpose of this study was to investigate some common single nucleotide polymorphisms (SNPs) in circadian rhythm genes (rs475715 of BMAL1/ARNTL, rs1026071, and rs228644 of PER3, rs3792152 of REV1, and rs7302060 of TIMELESS) as causative markers of ovarian cancer risk of in the population of Jammu and Kashmir in India. ResultsOur study included a total of 600 samples (200 cases and 400 age and sex-matched controls). Analysis of the genotype data from the selected SNPs indicated most significant association of rs3792152 of REV1 (OR=1.6, with 95% CI=0.12-1.2, p=0.0003) and rs4757151 of BMAL1/ARNTL (OR=1.847, with 95% CI=1.406-2.426, p=9.15E-06) with the ovarian cancer. The functional putative analysis revealed a significant regulatory effect of both these variants on other genes. ConclusionThese results suggest that some SNPs in circadian rhythm genes, particularly BMAL1/ARNTL and REV1, might be associated with the risk of ovarian cancer in the J&K population of North India.