bluuebunny/crossref_metadata_2025_split huggingface dataset:
Competence in information technology and the relationship with innovation capacity: a study in Brazilian technology-based companies
Authors: Alves Vorster Queiroga , Perez Gilberto 
Published: February 2025

Purpose
To evaluate the relationship between IT competence and innovation capacity in technology-based companies in Brazilian technology poles and/or parks in Brazil, this study aims to highlight the importance of the necessary differential associated with technologies to promote the innovation capacity of companies, as organisations can respond quickly and with innovative actions to changes in the business environment.

Design/methodology/approach
With a quantitative approach, an electronic questionnaire was applied from July to November 2021, with a ten-point Likert scale containing 45 questions distributed among the dimensions and constructs analysed. The survey sample was conducted in 88 companies (with 107 valid responses returned). Structural equation modelling was performed using SmartPLS 3.3.3 software for data analysis.

Findings
The results showed a strong, positive and committed relationship between IT competence and innovation capacity dimensions. As for the dimensions of IT competence, the six dimensions were evaluated and validated, with an advance in the literature.

Research limitations/implications
The limitations of this research are related to a specific group of companies, located in an environment and with their own characteristics. Due to the limitations, there is a need to expand the investigation to other business areas, and not only to technology-based companies. There is a need to examine in detail the resources, dimensions of IT competence that are applied in companies, as well as evaluate how they relate to the capacity for innovation.

Practical implications
It is believed that the results of this research can contribute to the improvement of actions and strategies of technology-based companies, in addition to improving market responses with greater dynamism, creating innovative products and/or services directly for customers. One cannot forget, however, the discussions and theoretical advances between the relations of constructs and their application in organisations of various sectors.

Social implications
The study of the existing relationships between IT competence and innovation capacity in Brazilian technology-based organisations provided an advance in knowledge, by understanding the form and characteristics existing between the dimensions analysed, enabling organisations to identify those that can best be used and obtain results of the company’s performance for the market.

Originality/value
The contributions include understanding the relationships between IT competence and innovation capacity and the knowledge that the organisation needs to know the dimensions of IT competencies to invest in innovation capacity and support activities for performance associated with a competitive advantage.
Eco-conscious consumers’ green real estate decisions in India: the role of social commerce
Authors: Anand Yashwin , Davidson Benny Godwin J. , George Jossy P. , Muttungal Peter V. 
Published: February 2025

PurposeThe primary purpose of this paper is to examine the role of perceived trust, information quality, positive word of mouth and societal norms toward real estate purchase intention. The study also examines how pro-environmental self-identity mediates the relationship between positive word of mouth and real estate purchase intent, as well as between societal norms and real estate purchase intention. This research aims to delve into these intricate dynamics through a multidimensional lens.Design/methodology/approachThe research employs existing scholarly works and measurable variables evaluated through a five-point Likert scale, hypothesis testing and mediation analysis to examine the proposed framework. A structured survey comprising six sections was administered, yielding 385 valid responses. The data analysis process included the use of confirmatory factor analysis and structural equation modelling techniques.FindingsThe analysis indicates that pro-environmental self-identity has the most significant influence on real estate purchase intention, closely followed by positive word of mouth. Incorporating eco-friendly themes in marketing campaigns significantly boosts purchase intentions. However, perceived trust does not significantly impact purchase intentions. Other factors, such as information quality and societal norms, also play significant roles, underscoring the importance of understanding the complex dynamics shaping consumer decisions in the real estate market.Research limitations/implicationsThis research exclusively targets responses from young consumers in specific regions of India. Future studies should aim for a more extensive geographic scope, encompassing a diverse global population for a broader understanding of the subject.Originality/valueBased on previous literature, this study is the first to identify the elements influencing the inclination to buy environmentally friendly real estate through social commerce.
Investor sentiment and its implication on global financial markets: a systematic review of literature
Authors: Maurya Prince Kumar , Bansal Rohit , Mishra Anand Kumar 
Published: February 2025

Purpose
This study aims to systematically review the literature on how various factors influence investor sentiment and affect financial markets. This study also sought to present an overview of explored contexts and research foci, identifying gaps in the literature and setting an agenda for future research.

Design/methodology/approach
The systematic literature investigation yielded 555 journal articles, with few other exceptional inclusions. The data have been extracted from the two databases, i.e. Scopus and Web of Science. For bibliometric analysis, VOSviewer and Biblioshiny by R have been used. The period of investigation is from 1985 to July 2023.

Findings
This systematic literature review helped us identify factors influencing investor sentiment and financial markets. This study has broadly classified these factors into two categories: rational and irrational. Rational factors include – economics and monetary policy, exchange rate, interest rates, inflation, government mandatory regulations, earning announcements, stock-split, dividend decisions, audit quality, environmental, social and governance aspects and ratings. Irrational factors include – behavioural and psychological factors, social media and online talk, news and entertainment, geopolitical and war events, calendar anomalies, environmental, natural disasters, religious events and festivals, irrationality caused due to government/supervisory body regulations, and corporate events. Using these factors, this study has developed an investor sentiment model. In addition, this review identified research trends, methodology, data and techniques used by researchers.

Originality/value
This review comprehensively explains how various factors affect investor sentiment and the stock market using the investor sentiment model. It further proposes an extensive future research agenda. This study has implications for stock market participants.
Retaining and engaging baby boomers in the workplace
Authors: Nichols Amy , Smith Simon M. 
Published: February 2025

Purpose
This paper aims to offer insights into how we should retain and engage baby boomers in the workplace through a deeper understanding of their expectations and needs.

Design/methodology/approach
The authors discuss a unique survey of 1,234 adults who work full- or part time across different age groups. Baby boomers data were compared to three other generational cohorts, namely, Millennials, Gen X and Gen Z.

Findings
Broad findings reveal that baby boomers value clear goals and expectations, regular feedback and a variety within their job roles. Furthermore, the authors highlight that baby boomers prioritise the following a lot less than younger generations: remote working and flexibility, diversity initiatives, career progression and pay rises and mental health benefits.

Originality/value
This research offers a unique empirical view of baby boomers against other generations leading to practical strategic HR recommendations.
Post‐TIPS Overt Hepatic Encephalopathy Increases Long‐Term but Not Short‐Term Mortality in Cirrhotic Patients With Variceal Bleeding: A Large‐Scale, Multicenter Real‐World Study
Authors: Xiang Yi , Tie Jun , Wang Guangchuan , Zhuge Yuzheng , Wu Hao , Zhu Xiaoli , Xue Hui , Liu Shanghao , Yang Ling , Xu Jiao , Zhang Feng , Zhang Mingyan , Wei Bo , Li Peijie , Wang Ze , Wu Wei , Chen Chao , Yang Shifeng , Han Yicheng , Tang Chengwei , Qi Xiaolong , Zhang Chunqing 
Published: February 2025

ABSTRACTBackgroundTransjugular intrahepatic portosystemic shunt (TIPS) is an established procedure for managing portal hypertension in cirrhotic patients, but the impact of post‐TIPS overt hepatic encephalopathy (OHE) on survival remains controversial. While its effect on short‐term survival is well‐documented, its long‐term implications remain unclear.AimsThis study aims to investigate the long‐term impact of post‐TIPS OHE on mortality in cirrhotic patients for variceal bleeding, focusing on the timing and predictive value of OHE beyond the first year post‐TIPS.MethodsA multicenter, retrospective cohort study was conducted involving 3262 cirrhotic patients who underwent TIPS for variceal bleeding at seven Chinese tertiary centers between January 2010 and June 2020. Clinical data, including demographics, procedure details, post‐TIPS complications and survival outcomes, were collected. The primary endpoints were all‐cause mortality and OHE, with follow‐up until death, liver transplantation or 60 months. Propensity score matching minimised confounding effects, and multivariate Fine‐Grey competing risk models identified independent mortality predictors.ResultsDuring a median follow‐up of 1077 days, 33.2% developed post‐TIPS OHE, associated with higher MELD and Child‐Pugh scores. Among these, 19.3% died, with a median time from OHE onset to death of 947 days. Post‐TIPS OHE was not linked to early survival (within 12 months) but emerged as an independent predictor of long‐term mortality beyond 24 months, consistent across various clinical scenarios.ConclusionPost‐TIPS OHE does not affect short‐term survival but significantly increases long‐term mortality risk. These findings highlight the need for continuous monitoring and tailored interventions to improve long‐term outcomes in post‐TIPS patients.
A review of the putative antiseizure and antiepileptogenic mechanisms of action for soticlestat
Authors: Kondo Shinichi , Murthy Venkatesha , Asgharnejad Mahnaz , Benitez Arturo , Nakashima Kosuke , Hawkins Nicole , White H. Steve 
Published: February 2025

AbstractSoticlestat (TAK‐935) is a potent and selective inhibitor of cholesterol 24‐hydroxylase (CYP46A1), an enzyme primarily expressed in the brain that catabolizes cholesterol to 24S‐hydroxycholesterol (24HC). In the ELEKTRA phase II clinical trial, soticlestat reduced seizure frequency in patients with developmental and epileptic encephalopathies, and two phase III studies evaluating the safety and efficacy of soticlestat in Dravet syndrome (SKYLINE) and Lennox–Gastaut syndrome (SKYWAY) have recently been completed. The exact mechanism of action by which soticlestat exerts pharmacological benefits remains undetermined. In this review, we assess the available preclinical evidence and present a working hypothesis for the antiseizure effects of soticlestat. The data support three potential mechanisms of action: (1) normalization of the seizure threshold via reduction of 24HC levels in the brain; as 24HC acts as a potent and selective positive allosteric modulator of glutamate N‐methyl‐D‐aspartate receptors, reduction of 24HC levels by soticlestat may lead to decreased hyperexcitability and elevated seizure thresholds; (2) restoration of glutamate sequestration from the synaptic cleft; accumulation of glutamate in the synaptic cleft enhances neural excitation and can contribute to neurotoxicity; soticlestat may inhibit conversion of cholesterol to 24HC in the membrane lipid raft microdomain and help to preserve it, consequently reducing excessive glutamate excitation; and (3) suppression of neuroinflammation via reduction of inflammatory cytokine release. These potential mechanisms of action warrant further investigation.
Can financial education programs alleviate household vulnerability to poverty? Evidence from the JinHui financial education project in China
Authors: Yang Ziying , Guo Man , Xiong Tian , Tang Manping 
Published: February 2025

AbstractThis paper investigates whether the JinHui financial education project (i.e., a large‐scale financial education program in China) reduces household vulnerability to poverty. Using data from the China Family Panel Studies and the JinHui Financial Education project data from the China Foundation for Development of Financial Education, we find that the JinHui project significantly reduces household vulnerability to poverty. Our economic channel analyses find that the JinHui project alleviates household vulnerability to poverty through improving household risk management ability. Interestingly, our mechanism analyses find no evidence that increasing household income is a mechanism through which the JinHui project reduces household vulnerability to poverty.
High‐Field Diffusion Tensor Imaging of Median, Tibial, and Sural Nerves in Type 2 Diabetes With Morphometric Analysis
Authors: Pušnik Luka , Gabor Aljoša , Radochová Barbora , Janáček Jiří , Saudek František , Alibegović Armin , Serša Igor , Cvetko Erika , Umek Nejc , Snoj Žiga 
Published: February 2025

ABSTRACTBackground and PurposeThe primary objective was to compare diffusion tensor imaging (DTI) scalar parameters of peripheral nerves between subjects with type 2 diabetes mellitus (T2DM) and those without diabetes. Secondarily, we aimed to correlate DTI scalar parameters with nerve morphometric properties.MethodsMedian, tibial, and sural nerves were harvested from 34 male cadavers (17 T2DM, 17 nondiabetic). Each nerve was divided into three segments. The initial segment was scanned using 9.4 Tesla MRI system (three‐dimensional pulsed‐gradient spin‐echo sequence). DTI scalars were calculated from region‐average diffusion‐weighted signals. Second segment was optically cleared, acquired with optical projection tomography (OPT), and analyzed for morphometrical properties. Toluidine‐stained sections were prepared from last segment, and axon‐ and myelin‐related properties were evaluated.ResultsDTI scalar parameters of median and tibial nerves were comparable between the groups, while sural nerves of T2DM exhibited on average 41% higher mean diffusivity (MD) (p = 0.03), 38% higher radial diffusivity (RD) (p = 0.03), and 27% lower fractional anisotropy (FA) (p = 0.005). Significant differences in toluidine‐evaluated parameters of sural nerves were observed between the groups, with a positive correlation between FA with fiber density (p = 0.0001) and with myelin proportion (p < 0.0001) and an inverse correlation between RD and myelin proportion (p = 0.003). OPT‐measured morphometric properties did not correlate with DTI scalar parameters.ConclusionsHigh‐field DTI shows promise as an imaging technique for detecting axonal and myelin‐related changes in small sural nerves ex vivo. The reduced fiber density and decreased myelin content, which can be observed in T2DM, likely contribute to observed FA reduction and increased MD/RD.
Small Arteries From Old Spontaneously Hypertensive Rats Exhibit Enhanced Endothelium‐Independent Vasodilatory Capacity and Reduced Stiffness
Authors: Ramirez‐Perez Francisco I. , Jurrissen Thomas J. , Augenreich Marc A. , Castorena‐Gonzalez Jorge A. , Morales‐Quinones Mariana , Foote Christopher A. , Nourian Zahra , Lateef Olubodun M. , Imkaew Natnicha , Sun Zhe , Hill Michael A. , Meininger Gerald A. , Padilla Jaume , Martinez‐Lemus Luis A. 
Published: February 2025

ABSTRACTObjectiveIn conduit arteries, aging and hypertension are associated with stiffening characterized by increased cytoskeletal F‐actin and endothelial dysfunction. Herein, we determined if this also happens at the level of the resistance vasculature.MethodsWe retrospectively compared the mechanical and structural characteristics of small arteries isolated from older hypertensive and younger normotensive (64.7 ± 2.8 vs. 32.1 ± 1.9 years old) human subjects. The intersection of aging and hypertension was studied in small mesenteric arteries from old (88 weeks of age) spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) normotensive rats.ResultsArteries from older hypertensive subjects were stiffer and had more F‐actin, relative to those from younger normotensives. Comparatively, arteries from old SHRs showed reduced stiffness and increased vasodilation to sodium nitroprusside without changes in F‐actin. Matrix metalloproteinase‐2 (MMP‐2) and ‐9 (MMP‐9) were increased in the SHR arteries and exposure of naive arteries to exogenous MMP‐2 and MMP‐9 augmented responsiveness to sodium nitroprusside and adenosine.ConclusionsIn conclusion, resistance arteries from old SHRs are softer and vasodilate more to exogenous nitric oxide than those of WKY rats. This improved endothelial‐independent vasodilation is associated with an increased vascular expression of MMP‐2 and MMP‐9. We further conclude that aging and hypertension effects on the microcirculation may vary between species and vascular beds.
Is Health Status in Patients With Chronic Disorders of the Gastrointestinal System Disease‐Specific? Results From an Integral Approach
Authors: Lemlijn‐Slenter Anja H. W. M. , van Iperen Luuk P. , Wijnands Karolina A. P. , Wolter Nico , de Rijk Angelique E. , Masclee Ad A. M. 
Published: February 2025

ABSTRACTBackgroundIn patients with chronic disorders of the gastrointestinal (GI) system, integral health is disturbed in all dimensions: physical, mental, quality of life, participation, meaningfulness, and daily functioning. In this group, three large subgroups are distinguished: Inflammatory Bowel Diseases (IBD), Hepato‐Pancreatico‐Biliary diseases (HPB), and NeuroGastroenterology and Motility (NGM) disorders.Our aim was to compare integral health status between these three subgroups. For the NGM group, we focused on patients with documented motility disorders, not on patients with functional GI‐disorders. We hypothesized that the NGM group will have lower scores for integral health status compared to the IBD and HPB groups.MethodsA prospective, observational, questionnaire study was performed in patients with chronic GI‐system disorders (IBD, HPB, and NGM) attending the Maastricht University Medical Center outpatient department. Validated questionnaires and patient file data were used to quantify six health dimensions.Key ResultsData from 416 patients were collected. In all domains, apart from meaningfulness, the NGM group (n = 93) had significantly (0.001 ≤ p ≤ 0.033) lower scores compared to the IBD (n = 174) and HPB (n = 149) groups. From the NGM group, 66% were malnourished, had symptoms of depression (36%) and anxiety (19%), and work participation was lowest (32%). Correlations between intra‐ and interdimensional parameters were moderate to strong apart from meaningfulness.Conclusions & InferencesCompared to patients with chronic IBD and HPB disorders, patients with NGM disorders have significantly lower scores in five of six dimensions of health: physical and mental well‐being, quality of life, daily functioning, and participation.
Uncomplicated Diverticulosis Is Not Associated With Abdominal Pain or Abnormal Bowel Habit—A Population‐Based Swedish Cohort Study
Authors: Alexandersson Bjarki T. , Jones Michael P. , Forsberg Anna , Hedin Charlotte R. H. , Järbrink‐Sehgal Ellionore , Walter Susanna , Talley Nicholas J. , Agreus Lars , Andreasson Anna , Schmidt Peter T. 
Published: February 2025

ABSTRACTBackgroundWhether uncomplicated diverticulosis gives rise to symptoms is controversial. Diary‐based studies of abdominal pain and stool habits in general populations are scarce, and we therefore investigated symptom patterns in diverticulosis from prospectively collected symptom diaries in a random sample of the general population who completed a research colonoscopy.MethodsIn the Swedish population‐based colonoscopy (PopCol) study, 745 individuals from the general population underwent a colonoscopy of which 130 had diverticulosis, and none had diverticulitis. Seven‐day symptom diaries were completed by 258 participants (age 54, women 64%) of which 50 had diverticulosis. The frequency and location of abdominal pain, bowel habit and other gastrointestinal symptoms were compared between individuals with and without diverticulosis using logistic regression.Key ResultsDiverticulosis was not associated with abdominal pain (OR 1.24, CI 0.61–2.55) or left lower quadrant (LLQ) abdominal pain (OR 1.59, CI 0.73–3.49). Pain duration and severity were not associated with diverticulosis. When individuals with diverticulosis had pain, it was more often in the LLQ (OR 2.45, CI 1.02–5.86) compared with those without diverticulosis. Diverticulosis was not linked to altered bowel habits. Irritable bowel syndrome prevalence was 16% in the diverticulosis group and 19% in the non‐diverticulosis group.Conclusions and InferencesParticipants with diverticulosis did not report more abdominal pain or more LLQ abdominal pain than participants without diverticulosis. Bowel habit was not abnormal in diverticulosis. Our results do not support that uncomplicated diverticulosis cause symptoms in individuals without a history of acute diverticulitis.
Influence of Estrus and Double Ovulations on Reproductive Efficiency in Summer, of Holstein Heifers on a 5‐Day Hormonal Synchronisation Protocol With and Without Intravaginal Progesterone Device
Authors: Revilla‐Ruiz Ángel , Carulla Patricia , Pérez‐Navarro Alejandro , Patrón‐Collantes Raquel , De Mercado Eduardo , de la Luz Pérez‐Solana María , González‐Martín Juan Vicente , Sebastián Francisco , Pérez‐Garnelo Sonia , Astiz Susana 
Published: February 2025

ABSTRACTThe influence of estrus and double ovulations of Holstein heifers on a 5d‐Co‐synch 72 h protocol during summer was explored. Cycling heifers on the 5d‐Co‐72 h synchronisation protocol were randomised to carry a progesterone device (116) from day 0 to day 5 of the synchronisation protocol or not (97), from them 100 and 84 underwent fixed‐time artificial insemination (FTAI). Another 70 heifers showed estrus before the first GnRH and were inseminated. Heifers were pregnant 34% (33/97) without device, 44.0% (51/116) with device and 44.3% (31/70) inseminated after estrus. Pregnancy per insemination (P/AI) tended to be higher (p = 0.059) inseminating after estrus than after FTAI without device. Three heifers without device and two with it showed double ovulation, four of which became pregnant. Pregnancy loss was similar among groups (0%–10%). P/AI was higher in heifers with estrus before FTAI (OR 13.96, p = 0.027), and with each additional day of age (OR 1.015; p = 0.015). The device was associated with higher progesterone on day 5, with more synchronised heifers, more ovulation frequency after first GnRH (96.6% vs. 84%, p = 0.007), and more heifers showing estrus before FTAI (96.0% vs. 85.7%, p = 0.018). Days to conception after first AI of the study, and after maximum three AIs were similar between synchronised groups, but significantly shorter in heifers inseminated after observed estrus. Fertility was higher in heifers that showed signs of estrus before accompanying the FTAI, while double ovulation seems not to be a major factor for fertility. An intravaginal device slightly improves efficiency under heat stress by increasing ovulation, progesterone, proportion of synchronised heifers and heifers showing estrus at AI.