bluuebunny/crossref_metadata_2025_split huggingface dataset:
Funkcionalni testi za oceno ravnotežnega organa
Authors: Sluga Metka , Hribar Manja , Battelino Saba 
Published: January 2021

Težave z ravnotežjem sodijo med pogoste vzroke za obisk pri zdravniku, njihov izvor pa je lahko precej raznovrsten. Na področju otorinolaringologije se posvečamo predvsem okvaram notranjega ušesa in ravnotežnega živca ter nakažemo morebitno centralno prizadetost ravnotežnega sistema. Za postavitev diagnoze pogosto ne zadostuje zgolj ena preiskava, pač pa je po navadi potrebna kombinacija različnih testov, s katerimi potrjujemo ali izključujemo prizadetost posameznih delov ravnotežnega sistema. V osnovi razlikujemo med testi, s katerimi ocenjujemo delovanje polkrožnih kanalčkov, in testi za oceno delovanja sakulusa in utrikulusa. Predstavljena je klinična raziskava, v kateri smo pri 1.042 bolnikih z jasno anamnezo za benigni paroksizmalni pozicijski vertigo le-tega dokazali v 36 %. Nujno je bilo opraviti še dodatna testiranja, ki jih predstavlja prispevek. Za razlago njihovih rezultatov se pogosto zanašamo na opazovanje in merjenje gibanja očesnih zrkel, pri čemer je pomembno poznavanje določenih refleksov za ohranjanje ravnotežja. Ob tem moramo upoštevati tudi simptome, ki jih navaja bolnik, in teste po potrebi dopolniti s slikovnodiagnostičnimi preiskavami. Natančne računalniške meritve in grafični zapisi danes nadomeščajo opazovanje s prostim očesom in subjektivno razlaganje opažanj preiskovalca.
¿Es posible abordar el folklore musical de otras comunidades autónomas en el segundo ciclo de Educación Infantil?
Authors: Sánchez García Adrián , Álava Redal Lidia 
Published: January 2021

En este texto pretendemos comprobar la posibilidad de que el alumnado escolarizado en el segundo ciclo de Educación Infantil experimente, dentro del contexto escolar y en función de lo que permitan los diferentes currículos españoles, el folclore musical de otra comunidad autónoma. Para ello, analizamos la normativa vigente en este ciclo de cada comunidad autónoma en torno a la didáctica del folclore y nos centramos en la especial casuística del flamenco, declarado Patrimonio Cultural de la Humanidad de la UNESCO.
In this text, we hope to verify the chance that preschool students experience, within the school context, the musical folklore of other regions, always depending on what the Spanish syllabus allow us. In order to do this, we analyze the current law in this course of every region about folklore teaching and we focus on special casuistry of flamenco, declared to be World Cultural Heritage by UNESCO.
Assessment of the Anemic Conditions during Pregnancy: A Study of Sukkur City, Sindh, Pakistan
Authors: Qazi Maryam , Dayo Abdullah , Ghoto Muhammad Ali , Arain Mudassar Iqbal , Shaikh Bilawal , Shaikh Abdul Aziz , Farooqui Muhammad Umair , Ahmed Waqar , Rajper Faraz Qurban , Arbani Rashid Ali 
Published: January 2021

Background: Anemia is pathological disorder caused by mal nutrition and it is very common among feminine gender during gestational period.
Objective: To investigate the prevalence of anemia among pregnant women, and identify the risk factors and symptoms of anemia in pregnancy.
Methodology: Descriptive cross-sectional study was carried out for 12 months from June 2018 to June 2019 at Sukkur Blood and Drugs donating Society Hospital in Sukkur Sindh. A total of 300 pregnant women with anemic condition were selected by purposive sampling method. Structured questionnaire was designed in order to collect nominal and ordinal information after getting consent from included patients. The collected information was interpreted by using statistical software SPSS version 24.00
Results: The result revealed that 82.3% of the women were diagnosed as anemic, categorized as mild, moderate and severe. Anemic condition was common among pregnant women with ages 26-35 years, 63.9%. Women with primary or secondary education were more prone to anemia. The pregnant women belongs to rural areas were more forwarded to anemia, 86.6%. The numbers of patients were seen more in second and thirds trimester of gestation while rate of anemia in primary gravida was 75.0% that increased to 81.8% in multigravida, and further increased to 91.5% in grand multiparity.
Conclusion: The prevalence of anemia was high in rural area of Sindh. Haemoglobin concentration was very much low in most of the pregnant female. The major cause of anemia in pregnant women was mal nutrition.
Effect of Low Fat Diet, Almonds, Green Coffee and Mackerel Fish on Obese Rats
Authors: Aboelnaga Shimaa M. H. , Khatoon Fahmida 
Published: January 2021

The present work was conducted to study the effect of low fat diet (LFD), almonds, green coffee, mackerel fish and the combination of all of them on loss of weight, lipid profile, serum glucose, leptin hormone, liver enzymes and kidney functions of obese rats.
Methods: In this research, researcher used normal male albino rats (n=42). This group of rats was divided into two major groups. The first group (n=6 rats) fed on standard diet and was considered as a group of negative control. The second group (n= 36 rat) fed high fat diet for six weeks on to induce of obesity. Rats in the second group were randomly assigned to six equal subgroups: Subgroup (1) fed on HFD (consist of 20% fat) and used as (control positive) 1; Subgroups (2) fed on LFD containing only (10% fat) and used as (control positive) 2. Subgroup The third sub-group feeds on low fat diet LFD containing (almonds, which provided the diet with 5% oil hydrogenated oils 4% and soy oil 1%). Subgroup (4) fed on LFD and treated each rat daily in this group with 3 ml green coffee. Subgroup (5) fed on LFD containing (mackerel fish, which provided the diet with 5% fat, hydrogenated oils 4% and soy oil 1%). Subgroup (6) fed on LFD containing (almonds which provided the diet with 5% oil and mackerel fish which provided the diet with 5% oil) and treated each rat daily in this group with 3 ml green coffee The obtained data were tested with one-way ANOVA (mean ± standard deviation and one-way ANOVA test) using SAS package and compared with each other using the LSD (least significant differences at P< 0.05.
Results: Body weight gain % of rats increased significantly by feeding on a high-fat diet, also, serum "glucose, leptin hormone, cholesterol, triglyceride, lipoprotein cholesterol except HDL-c, kidney functions, liver increased in rats fed on HFD, while high-density lipoprotein cholesterol decreased, in comparison with the group of negative control group fed on basal diet.
Conclusion: Treatment of obese rats with LFDs, LFDs containing almond, LFDs containing green coffee, LFDs containing mackerel fish, and obese rats treated with all these improved all parameters.
Disease‐Modifying Therapies and Coronavirus Disease 2019 Severity in Multiple Sclerosis
Authors: Sormani Maria P. , De Rossi Nicola , Schiavetti Irene , Carmisciano Luca , Cordioli Cinzia , Moiola Lucia , Radaelli Marta , Immovilli Paolo , Capobianco Marco , Trojano Maria , Zaratin Paola , Tedeschi Gioacchino , Comi Giancarlo , Battaglia Mario A. , Patti Francesco , Salvetti Marco ,   the Musc‐19 Study Group
Published: January 2021

ObjectiveThis study was undertaken to assess the impact of immunosuppressive and immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in people with multiple sclerosis (PwMS).MethodsWe retrospectively collected data of PwMS with suspected or confirmed COVID‐19. All the patients had complete follow‐up to death or recovery. Severe COVID‐19 was defined by a 3‐level variable: mild disease not requiring hospitalization versus pneumonia or hospitalization versus intensive care unit (ICU) admission or death. We evaluated baseline characteristics and MS therapies associated with severe COVID‐19 by multivariate and propensity score (PS)‐weighted ordinal logistic models. Sensitivity analyses were run to confirm the results.ResultsOf 844 PwMS with suspected (n = 565) or confirmed (n = 279) COVID‐19, 13 (1.54%) died; 11 of them were in a progressive MS phase, and 8 were without any therapy. Thirty‐eight (4.5%) were admitted to an ICU; 99 (11.7%) had radiologically documented pneumonia; 96 (11.4%) were hospitalized.After adjusting for region, age, sex, progressive MS course, Expanded Disability Status Scale, disease duration, body mass index, comorbidities, and recent methylprednisolone use, therapy with an anti‐CD20 agent (ocrelizumab or rituximab) was significantly associated (odds ratio [OR] = 2.37, 95% confidence interval [CI] = 1.18–4.74, p = 0.015) with increased risk of severe COVID‐19. Recent use (<1 month) of methylprednisolone was also associated with a worse outcome (OR = 5.24, 95% CI = 2.20–12.53, p = 0.001). Results were confirmed by the PS‐weighted analysis and by all the sensitivity analyses.InterpretationThis study showed an acceptable level of safety of therapies with a broad array of mechanisms of action. However, some specific elements of risk emerged. These will need to be considered while the COVID‐19 pandemic persists. ANN NEUROL 2021;89:780–789
Organelle‐Specific Photoactivation of DNA Nanosensors for Precise Profiling of Subcellular Enzymatic Activity
Authors: Shao Yulei , Zhao Jian , Yuan Jinying , Zhao Yuliang , Li Lele 
Published: January 2021

AbstractUnderstanding of the functions of enzymes in diverse cellular processes is important, but the design of sensors with controllable localization for in situ imaging of subcellular levels of enzymatic activity is particularly challenging. We introduce herein a spatiotemporally controlled sensor technology that permits in situ localization and photoactivated imaging of human apurinic/apyrimidinic endonuclease 1 (APE1) within an intracellular organelle of choice (e.g., mitochondria or nucleus). The hybrid sensor platform is constructed by photoactivatable engineering of a DNA‐based fluorescent probe and further combination with an upconversion nanoparticle and a specific organelle localization signal. Controlled localization and NIR‐light‐mediated photoactivation of the sensor “on demand” effectively constrains the imaging signal to the organelle of interest, with improved subcellular resolution. We further demonstrate the application of the nanosensors for the imaging of subcellular APE1 translocation in response to oxidative stress in live cells.
Interpenetrating polymer network/functionalized‐reduced graphene oxide nanocomposite: As an advanced functional material
Authors: Ghosh Tuhin , Karak Niranjan 
Published: January 2021

AbstractIn this report, smart polyurethane‐polystyrene interpenetrating polymer network (IPN)‐based nanocomposites were fabricated using simultaneous polymerization technique with different doses of functionalized reduced graphene oxide (f‐RGO). RGO was functionalized with monoglyceride of sunflower oil in the presence of toluene diisocyanate. Successful functionalization of RGO was supported by Fourier‐transform infrared spectroscopy, X‐Ray diffraction, and transmission electron microscopy analyses. Most interestingly, the fabricated IPN‐based nanocomposites showed significant enhancements in mechanical (tensile strength: 165%; elongation at break: 198%; toughness: 340%) and thermal (thermally stable up to 262°C) properties upon incorporation of 1 weight% of f‐RGO. Moreover, the fabricated nanocomposites exhibited outstanding chemical resistance, self‐cleaning behavior through surface hydrophobicity (static contact angle: 125.6–136.5°), multi‐stimuli responsive shape memory effect (100% recovery within 33–44 s by microwave and 265–308 s by sunlight) and thermally actuated artificial muscle‐like behavior. Therefore, the studied smart nanocomposites with the aforementioned properties hold significant potential for possible advanced applications.
Precision cosmology in modified and extended theories of gravity: An insightful test
Authors: Escamilla‐Rivera Celia 
Published: January 2021

AbstractIn this work, we present a brief discussion about modified and extended cosmological models using current observational tests. We show that, according to these astrophysical samples based on late universe measurements, theories like f(R) and f(T, B) can provide a useful interpretation of a dynamical dark energy. At this stage, precision cosmostatistics has also become a well‐motivated endeavor by itself to test gravitational physics at cosmic scales, and these analyses can be employed to test the viability and future constrains over specific cosmological models of these theories of gravity, making them a good approach to propose an alternative path from the standard ΛCDM scenario.
Energy conditions in non‐minimally coupled f(R, T) gravity
Authors: Sahoo Pradyumn Kumar , Mandal Sanjay , Arora Simran 
Published: January 2021

In today's scenario, going beyond Einstein's theory of gravity leads us to some more complete and modified gravity theories. One of them is the f(R, T) gravity in which R is the Ricci scalar, and T is the trace of the energy‐momentum tensor. Using a well‐motivated linear f(R, T) gravity model with a single parameter, we studied the strong energy condition (SEC), the weak energy condition (WEC), the null energy condition (NEC), and the dominant energy condition (DEC) under the simplest non‐minimal matter geometry coupling with a perfect fluid distribution. The model parameter is constrained by energy conditions and a single‐parameter proposed equation of state (EoS), resulting in the compatibility of the f(R, T) models with the accelerated expansion of the universe. It is seen that the EoS parameter illustrates the quintessence phase in a dominated accelerated phase, pinpoint to the cosmological constant yields as a prediction the phantom era. Also, the present values of the cosmological constant and the acceleration of the universe are used to check the viability of our linear f(R, T) model of gravity. It is observed that the positive behavior of DEC and WEC indicates the validation of the model. In contrast, SEC is violating the condition resulting in the accelerated expansion of the universe.
Integratives computerbasiertes Planen und Bauen: Architektur digital neu denken
Authors: Knippers Jan , Kropp Cordula , Menges Achim , Sawodny Oliver , Weiskopf Daniel 
Published: January 2021

AbstractDie Herausforderung an das Bauen der Zukunft besteht darin, mehr zu bauen, dabei weniger Schadstoffe zu emittieren und weniger endliche Ressourcen zu verbrauchen und trotzdem eine qualitätsvolle und lebenswerte gebaute Umwelt zu schaffen. In einem sich wechselseitig beeinflussenden Prozess müssen hierfür sowohl die Produktivität der Bauprozesse als auch die Energie‐ und Ressourceneffizienz der Bausysteme verbessert werden. Digitale Technologien bieten neue Lösungsansätze für diese Herausforderungen. Ziel des Exzellenzclusters IntCDC an der Universität Stuttgart und dem Max‐Planck‐Institut für Intelligente Systeme ist es, das volle Potenzial digitaler Technologien zu nutzen, um das Planen und Bauen in einem integrativen und interdisziplinären Ansatz neu zu denken und damit die methodischen Grundlagen für eine umfassende Modernisierung des Bauschaffens zu legen. Eine zentrale Zielsetzung ist die Entwicklung einer übergeordneten Methodologie des „Co‐Design“ von Methoden, Prozessen und Systemen, basierend auf interdisziplinärer Forschung zwischen den Bereichen Architektur, Bauingenieurwesen, Ingenieurgeodäsie, Produktions‐ und Systemtechnik, Informatik und Robotik sowie Geistes‐ und Sozialwissenschaften. So sollen Lösungswege für die ökologischen, ökonomischen und sozialen Herausforderungen aufgezeigt und die Voraussetzungen für eine qualitätsvolle, lebenswerte und nachhaltige gebaute Umwelt sowie für eine digitale Baukultur geschaffen werden.
A multi‐method evaluation of the implementation of a cancer teamwork assessment and feedback improvement programme (MDT‐FIT) across a large integrated cancer system
Authors: Taylor Cath , Harris Jenny , Stenner Karen , Sevdalis Nick , Green James SA 
Published: January 2021

AbstractBackgroundGlobally, Multidisciplinary Teams (MDTs) are considered the gold standard for diagnosis and treatment of cancer and other conditions, but variability in performance has led to demand for improvement tools. MDT‐FIT (Multidisciplinary Team Feedback for Improving Teamwork) is an improvement programme developed iteratively with over 100 MDTs (≥1100 MDT‐members). Complex interventions are often adapted to context, but this is rarely evaluated. We conducted a prospective evaluation of the implementation of MDT‐FIT across an entire integrated care system (ICS).MethodsMDT‐FIT was implemented within all breast cancer MDTs across an ICS in England (n = 10 MDTs; 275 medical, nursing, and administrative members). ICS managers coordinated the implementation across the three stages of MDT‐FIT: set up; assessment (self‐report by team members plus independent observational assessment); team‐feedback and facilitated discussion to agree actions for improvement. Data were collected using process and systems logs, and interviews with a purposively selected range of participants. Analysis was theoretically grounded in evidence‐based frameworks for implementation strategies and outcomes.ResultsAll 10 MDTs participated in MDT‐FIT; 36 interviews were conducted. Data from systems and process logs covered a 9‐month period. Adaptations to MDT‐FIT by the ICS (e.g., coordination of team participation by ICS rather than individual hospitals; and reducing time protected for coordination) reduced Fidelity and Adoption of MDT‐FIT. However, the Acceptability, Appropriateness and Feasibility of MDT‐FIT remained high due to embedding implementation strategies in the development of MDT‐FIT (e.g., stakeholder engagement, interactive support).ConclusionsThis is a unique and comprehensive evaluation of the multi‐site implementation of a complex team improvement programme. Findings support the imperative of considering implementation strategies when designing such programmes to minimize potentially negative impacts of adaptations in “real world” settings.
Influence of bath composition on the electrodeposition of amorphous Ni‐Mo alloys using potassium‐sodium tartrate as complexing agent
Authors: Filgueira de Almeida Arthur , da Costa Neto Heleno , de Santana Renato Alexandre Costa , Alves José Jaílson Nicácio , Nascimento Campos Ana Regina , Prasad Shiva 
Published: January 2021

AbstractCurrently, sodium citrate is the most used complexing agent for electrodeposition of Ni‐Mo coatings, especially for studying the effect of bath temperature and current density on the proprieties of Ni‐Mo coatings. This study evaluates the influence of the concentrations of nickel sulphate and sodium molybdate on the electrodeposition of Ni‐Mo alloys in baths using tartrate as a complexing agent. Electrodepositions were carried out in a two‐electrode cell. A 32 complete factorial design of experiments along with response surface methodology (RSM) was used for the optimization of bath variables for electrodeposition of Ni‐Mo alloys. The coatings obtained were characterized in terms of chemical composition and surface morphology. The chemical composition of the coatings was most influenced by the sodium molybdate concentration. Ni‐Mo coatings of good quality were obtained in potassium‐sodium tartrate baths with Mo content in the range 18‐44 wt%; some results present even higher Mo content than coatings obtained from citrate baths. The coating with the highest Mo content was deposited from the bath with a concentration ratio of nickel sulphate to sodium molybdate of 1:1. Surface morphology varied according to chemical composition, and microcracks were observed for the coating with 41 wt% Mo, for which scanning electron microscopy (SEM) images also show the presence of nodules. The most homogeneous coating surface was obtained at a concentration ratio of nickel sulphate to sodium molybdate of 10:3. X‐ray diffraction analyses have shown that all coatings obtained in this work are amorphous.
Experimental visualization of reversible magnesium storage and surface chemistry of magnesium silicide anode
Authors: Hoang Van‐Kien , Chung Gyeong Jun , Oh Min‐Geun , Song Seung‐Wan 
Published: January 2021

AbstractMagnesium silicide (Mg2Si) is a new anode material candidate for Mg‐ion batteries due to the Earth‐abundance of Mg and Si and its high theoretical specific capacity of 1398 mAh/g. However, to date, no one reported its reversible Mg‐storage ability. Herein, we demonstrate for the first time the experimental visualization of a reversible electrochemical demagnesiation and magnasiation of Mg2Si film model electrode in a half‐cell with the electrolyte of PhMgCl/THF at room temperature. The Mg2+‐diffusivity, 1.3 × 10–18 cm2/s, of Mg2Si film model electrode determined with cyclic voltammetry is four orders of magnitude lower than that of Li+‐diffusivity of Mg2Si film electrode in a lithium cell, indicating a sluggish diffusion kinetics. Surface chemistry studies of the 1st discharged (demagnesiated) and the 1st cycled (re‐magnesiated) electrodes utilizing X‐ray photoelectron spectroscopy reveal that the surface of pristine Mg2Si is highly covered by various silicon oxides, and Mg2Si undergoes segregation and phase separation partly to Mg and Si along with the surface coverage of electrolyte decomposition products. Those events lower the homogeneity and connectivity of electrode composition, which limits the reaction reversibility. The data give insight into a new material design for Mg‐ion batteries.
Protein diets with the role of immune and gut microbial regulation alleviate DSS‐induced chronic ulcerative colitis
Authors: Ma Shenyan , Qian Cheng , Li Nan , Fang Zhifeng , Zhao Jianxin , Zhang Hao , Chen Wei , Liu Zhenmin , Lu Wenwei 
Published: January 2021

AbstractThe association between diet and inflammatory bowel disease (IBD) has been confirmed. However, the role of protein consumption in IBD remains controversial. This research aimed to explore the effects of milk‐based protein (MBP), potato protein (PP), and mixed protein (MP) on the recovery of mice with dextran sulfate sodium (DSS)‐induced ulcerative colitis (UC). MP alleviated UC symptoms through reducing colon shortening and tissue damage, decreasing neutrophil infiltration, maintaining the mucous layer integrity, and suppressing the expression of TNF‐α, IL‐17A, IL‐6, and IL‐1β. MBP and PP decreased the colon shortening and IL‐1β levels but PP increased the MUC2 expression. Additionally, the gut microbial structure and composition were altered after different proteins supplement. Compared to DSS‐treated mice, MP‐treated mice showed that increased abundances in Coprococcus and Bifidobacterium and decreased abundances in Sutterella, Lactobacillus, and Akkermansia. MBP increased the proportion of Bifidobacterium and reduced Sutterella, but PP increased Ruminococcus and Bifidobacterium and decreased Adlercreutzia. Correspondence analysis of gut microbial composition to determine the effects of protein diets on immune response and pathological characteristics also verified the interaction between gut microbiota and alleviation of colitis. These results provide a theoretical basis for the selection of raw materials for clinical enteral nutrition preparations and potential use for potato protein wastes.