bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementing advance care planning in heart failure: a qualitative study of primary healthcare professionals
Authors: Schichtel Markus , MacArtney John I , Wee Bee , Boylan Anne-Marie 
Published: February 2021

BackgroundAdvance care planning (ACP) can improve the quality of life of patients suffering from heart failure (HF). However, primary care healthcare professionals (HCPs) find ACP difficult to engage with and patient care remains suboptimal.AimTo explore the views of primary care HCPs on how to improve their engagement with ACP in HF.Design and settingA qualitative interview study with GPs and primary care nurses in England.MethodSemi-structured interviews were conducted with a purposive sample of 24 primary care HCPs. Data were analysed using reflexive thematic analysis.ResultsThree main themes were constructed from the data: ACP as integral to holistic care in HF; potentially limiting factors to the doctor–patient relationship; and approaches to improve professional performance. Many HCPs saw the benefits of ACP as synonymous with providing holistic care and improving patients’ quality of life. However, some feared that initiating ACP could irrevocably damage their doctor–patient relationship. Their own fear of death and dying, a lack of disease-specific communication skills, and uncertainty about the right timing were significant barriers to ACP. To optimise their engagement with ACP in HF, HCPs recommended better clinician–patient dialogue through question prompts, enhanced shared decision-making approaches, synchronising ACP across medical specialties, and disease-specific training.ConclusionGPs and primary care nurses are vital to deliver ACP for patients suffering from HF. HCPs highlighted important areas to improve their practice and the urgent need for investigations into better clinician–patient engagement with ACP.
Factors associated with potentially missed acute deterioration in primary care: cohort study of UK general practices
Authors: Cecil Elizabeth , Bottle Alex , Majeed Azeem , Aylin Paul 
Published: February 2021

BackgroundIn the UK, while most primary care contacts are uncomplicated, safety incidents do occur and result in patient harm, for example, failure to recognise a patient’s deterioration in health.AimTo determine the patient and healthcare factors associated with potentially missed acute deterioration in health.Design and settingCohort of patients registered with English Clinical Practice Research Datalink general practices between 1 April 2014 and 31 December 2017 with linked hospital data.MethodA potentially missed acute deterioration was defined as a patient having a self-referred admission to hospital having been seen in primary care by a GP in the 3 days beforehand. All diagnoses and subsets of commonly-reported missed conditions were analysed..ResultsA total of 116 097 patients contacted a GP 3 days before an emergency admission. Patients with sepsis (adjusted odds ratio [aOR] 1.09, 95% confidence interval [CI] = 1.01 to 1.18) or urinary tract infections (aOR 1.09, 95% CI = 1.04 to 1.14) were more likely to self-refer. The duration of GP appointments was associated with self-referral. On average, a 5-minute increase in appointment time resulted in a 10% decrease in the odds of self-referred admissions (aOR 0.90, 95% CI = 0.89 to 0.91). Patients having a telephone consultation (compared with face-to-face consultation) (aOR 1.14, 95% CI = 1.11 to 1.18) previous health service use, and presence of comorbidities were also associated with self-referred admission.ConclusionDifferentiating acute deterioration from self-limiting conditions can be difficult for clinicians, particularly in patients with sepsis, urinary tract infections, or long-term conditions. The findings of this study support the call for longer GP consultations and caution against reliance on telephone consultations in primary care; however, more research is needed to understand the underlying mechanisms.
La pilule perpétuelle l’est-elle vraiment ?
Authors: Lafont Olivier 
Published: February 2021

La pilule d’antimoine était appelée pilule perpétuelle, parce qu’elle pouvait être récupérée et réutilisée après usage. Cet adjectif était-il justifié ? De nombreux
auteurs ont tenté de répondre à cette question. Thibaut dit Le Lorrain a décrit en détail la façon de préparer la pilule d’antimoine et son usage. Il pensait qu’elle ne subissait aucune dégradation. Glaser partageait cette opinion, mais Nicolas Lémery avait remarqué que le poids de la pilule décroissait légèrement au cours de son utilisation et qu’après maints usages, il était nécessaire de limer sa surface pour restaurer son activité. Au cours du XVIIIe siècle, la pilule d’antimoine commença à être considérée comme dangereuse à utiliser. Au XIXe siècle, elle était uniquement considérée comme un médicament historique. La pilule d’antimoine n’était donc pas véritablement perpétuelle, puisqu’elle subissait une dégradation et que son emploi a été limité à une période relativement courte.
L’éducation thérapeutique du patient à l’officine : retour sur un siècle de pédagogie
Authors: Raynal Cécile 
Published: February 2021

The therapeutic education of the patient in the pharmacy : return on one century of pedagogy – The chemist is a health educator. Its mission of therapeutic education of the patient (inscribed in the French Code of the public health since 2009) helps the patients to become actors of their medical care. The understanding of pathologies, their prevention and their treatments, leads to the improvement of the entire healthcare system. This article traces the history of the progressive construction of the concept of therapeutic education of the patient at the pharmacy, in France, during the twentieth century. This study is based on a corpus of brochures for patients (almanachs, booklets) distributed initially by some pharmacies concerned with their advertising ; but also over twenty years of the newsletter Info Santé (1977-1997) produced by the CESSPF. This article presents also
three iconic pharmaceutical figures in health education : Dr Pierre Rolland, Pr André Quevauviller
et the chemist Janine Dufouil.
Origines et émergence de l’American Way of Pharmacy
Authors: Saxce Marguerite de , Gaslonde Thomas 
Published: February 2021

L’American Way of Pharmacy est souvent caractérisé par un attachement très particulier au principe de Liberté si cher aux Américains. Mais la pratique de la pharmacie en Amérique du Nord s’inscrit dans une longue séquence d’événements qui démarrent dès l’époque des premières tribus amérindiennes. La découverte du nouveau continent a entrainé une colonisation trop rapide pour que la société structure le marché des médicaments, tel que déjà fonctionnel en Europe. Pendant que la pharmacopée locale émerveillait explorateurs et botanistes, l’implication de simples commerçants a permis de couvrir les besoins sur l’ensemble du territoire. Et c’est seulement avec la mise en place du Collège de Philadelphie en 1821, que les nouveaux professionnels en pharmacie ont commencé à s’organiser en associations, dans l’objectif de contrôler
la formation et l’accès au métier. Cette période charnière est finalement bien documentée, et l’analyse
de la structuration de la profession en parallèle à l’obtention d’indépendance des États-Unis et du Canada, donne un nouvel éclairage à la société pharmaceutique des temps modernes.
Un pharmacien français à New-York : Edmond Fougera (1821-1889), importateur de spécialités françaises et créateur d’une firme pharmaceutique aux États-Unis
Authors: Devaux Guy 
Published: February 2021

A French pharmacist in New-York : Edmund Fougera (1821-1889), importer of French patented medicines and creator of a pharmaceutical company in the USA – Edmund Fougera, who immigrated
to the United-States in 1846, opened two pharmacies in Brooklyn and New-York City, and was
simultaneously a pharmacist at Long Island College Hospital. At the same time he played an important role in disseminating French pharmaceutical specialties to the United States, of which he was
often the sole importer. He developed a whole range of his own medicines, which led him to create an amecican pharmaceutical firm that still exists today under the name of Fougera Pharmaceuticals Inc.. after his takeover by an international group. Finally, it shoud be noted that it played a role in the dissemination in Europe of vaseline as a dermatological excipient.
SARS-CoV-2 and autoimmune rheumatic diseases
Authors: Stoilov Nikolay , Boyadzhieva Vladimira 
Published: February 2021

Coronaviruses have been known to mankind for decades, accounting for about a third of flu-like illnesses each year in the early fall-winter period. At the end of 2019, a new coronavirus ( SARS – CoV-2) was found, which in March 2020 was declared pandemic by the World Health Organization (WHO). The structure of the new virus continues to be studied, but the S-protein has been shown to play a major role in the pathogenesis of the disease it causes. Using the S-protein a host is attached to the cell. The severity of COVID-19 varies from individual to individual, but the main risk factors are age, sex, comorbidities and etc.
At present, the question of whether the patients with autoimmune disease are at greater risk of severe COVID-19, remains unclear. The development of an effective vaccine give hope to society, but also raises a number of questions about long-term safety.
HAK ASASI MANUSIA DALAM KONSTITUSI INDONESIA
Authors: Muni Abd 
Published: February 2021

Latar belakang lahirnya sebuah konstitusi yaitu berangkat dari kontrak sosial atau general egreement antara mayoritas rakyat terkait konstruksi yang diidealkan oleh sebuah negara. Konstitusi tersebut dibutuhkan oleh warga negara untuk mengakomudir kepentingan mereka bersama agar dapat dilindungi. Adapun kepentingan yang paling fundamental dari setiap warga negara yaitu perlindungan terhadap Hak Asasi Manusia (HAM) yang menjadi salah satu bagian sentral di dalam konstitusi. Dalam hal ini, konstitusi tidak hanya sebatas memberikan jaminan dan proteksi hitam di atas putih, melainkan wajib memberikan garansi berbagai nilai dan norma yang dijadikan rujukan oleh lembaga peradilan dalam menunaikan tugasnya sebagai Wakil Tuhan di muka bumi.
The existence of a constitution is from a social contract or general egreement between people related to the idealized construction of a country. The constitution is needed by citizens to communicate their common interests to be protected. The most fundamental interests of citizens are protection of human rights (HAM) which is one of the important parts of the constitution. In this case, the constitution not only provides guarantees and protection in black and white, but also must provide guarantees of various values and norms used as a reference by the judiciary in fulfilling its duties as God's Representative on earth.
What is History is What is Illustrated. The Utilization and Function of Images in History Coursebooks in Poland and Britain.
Authors: Shaw Aeddan 
Published: February 2021

In a society which is increasingly visual, and the teaching of history and critical thinking so important in an age of post-truth and fake news, the words of the Swedish poet, Linn Hansén, seem particularly apt: what is history, is what is illustrated. The images found in history coursebooks help learners to imagine the past, providing a visual aid to support learning, but they can also be used to foster critical thinking by treating the images as historical sources in themselves.
This paper presents the results of a pilot study conducted on the functions of images contained in Polish and British history coursebooks using a proprietary paradigm developed on the basis of existing scholarship in English Language Teaching. It shows that the pedagogical functions of images in history coursebooks vary greatly between the two educational contexts. In Britain, images are typically treated as historical sources in themselves, whilst in Poland they typically perform more of a decorative function. The paper closes with a number of recommendations for further research and publishers of history coursebooks.
Motivation of Early Childhood Education Teachers in the Pursuit of Pedagogical Mastery
Authors: Szkolak-Stępień Anna 
Published: February 2021

The article concerns the role of motivation among early education teachers in striving for pedagogical mastery. The aim of the exploratory research was to outline the motives of early childhood education teachers in their pursuit of pedagogical mastery. The main challenge was to determine what factors motivate a teacher to strive for excellence and what methods are used to achieve it. This question was answered by collecting empirical evidence from January to May 2019. The research conducted by the author was of a mixed nature (quantitative and qualitative).
The findings suggest that there are many motives for Polish teachers of early childhood education to achieve pedagogical mastery, but chief among them is financial gratification. In Poland, the amount of remuneration depends on one’s professional degree. A professional career and its further advancement is balanced with the journey to achieve pedagogical mastery.
La mediación en el proceso contencioso-administrativo. Una perspectiva comparada entre el derecho portugués y el derecho español
Authors: Valiño Ces Almudena 
Published: February 2021

El derecho administrativo ha pervivido históricamente sin incorporar la mediación, pero lo cierto es que no puede negarse que, con el paso del tiempo, las relaciones jurídico-administrativas son cada vez más complejas y el modelo actual no da respuesta a las necesidades de la ciudadanía, por los resultados poco satisfactorios y por los tiempos que se demoran.
Esta realidad favorece la sensación de desprotección de los ciudadanos frente a la Administración y la necesidad de buscar nuevos mecanismos para la resolución de controversias. Esto no hace sino merecer el análisis de la posibilidad de acudir a una mediación, tanto en el derecho español como en el portugués, para solventar los conflictos que ante los juzgados y tribunales administrativos se plantean.
Development of a medical education podcast in obstetrics and gynecology
Authors: Black Kristin , Drummond Lindsay , Jain Venu , Sagle Margaret 
Published: February 2021

Implication Statement:
Podcasts are used in medical education to supplement conventional teaching methods such as lectures and reading. We identified a lack of Canadian medical education podcasts covering obstetrics and gynecology (Ob/Gyn) content and created a podcast specific for Canadian medical students and residents. The podcast called “OB-G in YEG” is freely available and currently has fourteen episodes that cover common topics in Ob/Gyn. We describe the process for creating a high-quality medical education resource that is widely accessible to learners that readers may be able to replicate in their own discipline.
Estudio de los aspectos económicos y ambientales de la gestión de residuos sólidos de actividades de construcción y demolición en la municipalidad distrital de Miraflores, Arequipa - 2016
Authors: Hinojosa Pérez Anatolia Hortencia , Meza Muñoz Pedro Anderson 
Published: February 2021

El objetivo de esta investigación ha sido realizar un estudio de los aspectos económicos y ambientales de la gestión de residuos sólidos en las actividades de construcción y demolición en la Municipalidad Distrital de Miraflores, Arequipa – 2016. Este estudio nos permite proponer alternativas estratégicas bajo el enfoque del ciclo de vida, en base a experiencias a nivel nacional e internacional. La metodología es de tipo mixta, es decir cuantitativa porque se analiza información estadística, y cualitativa, de diseño no experimental, de tipo transversal y de nivel descriptivo. Nuestra población objetivo han sido los generadores y responsables de residuos de la construcción y demolición de la Municipalidad Distrital de Miraflores. Se emplearon Los resultados obtenidos, en base al diagnóstico situacional, permitirán contar con la conceptualización de residuos sólidos y sus tipos, fuentes generadoras, así como quiénes son los responsables. Asimismo, se determinar los aspectos económicos y los efectos ambientales de la mala gestión de residuos y en base a estos resultados identificar alternativas estratégicas de gestión que se replique en todas las municipalidades de la región Arequipa.
Características de gestión, controles gerenciales y de rendimiento de empresas MyPES
Authors: Della Giustina Felipe André , Andrade dos Santos Edicreia , Lunkes Rogério João , Da Rosa Fabricia Silva , Bertamoni Guilherme 
Published: February 2021

En este estudio se evidencia la importancia del uso de los controles gerenciales como herramientas de gestión contable-financiera de modo que permitan orientar a los empresarios de las micro y pequeñas empresas a mantenerse en el mercado de forma competitiva. El estudio tiene como objetivo verificar las características de gestión, controles gerenciales y de desempeño de las empresas MyPES del rubro alimenticio. Se realizó una investigación por encuestas con los gestores, en 31 empresas del rubro alimenticio, como bares y restaurantes de la ciudad de Florianópolis, Santa Catarina. En el análisis de los datos se utilizó estadística descriptiva. Los resultados evidenciaron que la mayoría de las empresas utilizan los controles gerenciales como herramientas de gestión y control del rendimiento, para que puedan colocar en práctica sus acciones, buscando alcanzar sus objetivos. El uso de los controles gerenciales en todas las esferas de la empresa contribuye al buen desempeño de la organización; sin embargo, el estudio reveló también, que algunas empresas aún necesitan ayuda en relación al uso de los controles gerenciales para dar un norte a sus acciones y alinear sus objetivos.
PENGARUH ELECTRONIC WORTH OF MOUTH TERHADAP CITRA PERUSAHAAN GADGET DI KOTA BATAM
Authors: Hasan Golan , Karina Karina 
Published: February 2021

In conducting of this research, has the purpose of knowing the factors that influence purchase intention. eWOM Credibility, eWOM Quality, eWOM Quantity, Corporate Image as mediating role are factors that will be examined and analyzed. The object of this research is smartwatch that ocated in Batam City with certain criteria that using media social active. Purposive sampling is the method in this study, selected are adjusted to the research objectives. The data analysis in this research is PLS-SEM (Partial Least Square Structural Equation Modelling). The result of this research is indicate that the eWOM Quality, eWOM Quality, Corporate Image are able to influence significantly on Purchase Intention while eWOM Credibility doesn’t have a strong effect and maybe influence by other variables on Purchase Intention. In addition Corporate Image’s able to mediate eWOM Credibility, eWOM Quality, eWOM Quality and Purchase Intention.
Reprocessing of a Green Bank 43 m Telescope Survey of Unidentified Bright Radio Sources for Pulsars and Radio Bursts
Authors: Crawford Fronefield , Margeson James , Nguyen Benjamin , Saigal Tanya , Young Olivia , Agarwal Devansh , Aggarwal Kshitij 
Published: February 2021

Abstract
We have reprocessed a set of observations of 75 bright, unidentified, steep-spectrum polarized radio sources taken with the Green Bank 43 m telescope to find previously undetected sub-millisecond pulsars and radio bursts. The (null) results of the first search of these data were reported by Schmidt et al.. Our reprocessing searched for single pulses out to a dispersion measure (DM) of 1000 pc cm−3 which were classified using the Deep Learning based classifier fetch. We also searched for periodicities at a wider range of DMs and accelerations. Our search was sensitive to highly accelerated, rapidly rotating pulsars (including sub-millisecond pulsars) in compact binary systems as well as to highly dispersed impulsive signals, such as fast radio bursts. No pulsars or astrophysical burst signals were found in the reprocessing.
Testing Short-term Variability and Sampling of Primary Volatiles in Comet 46P/Wirtanen
Authors: Khan Younas , Gibb Erika L. , Bonev Boncho P. , Roth Nathan X. , Saki Mohammad , DiSanti Michael A. , Russo Neil Dello , Vervack Ronald J. , McKay Adam J. , Combi Michael R. , Shou Yinsi , Cordiner Martin A. , Kawakita Hideyo , Fougere Nicolas , Protopapa Silvia 
Published: February 2021

Abstract
The exceptionally favorable close approach of Jupiter-family comet 46P/Wirtanen in 2018 December enabled characterization of its primary volatile composition with exceptionally high spatial resolution and sensitivities using the iSHELL spectrograph at the NASA Infrared Telescope Facility on Maunakea, HI. We sampled emissions from H2O, HCN, C2H2, NH3, C2H6, and CH3OH on UT 2018 December 21 using two instrumental settings that spanned the 2.9–3.6 μm spectral region. We also obtained a sensitive 3σ upper limit for H2CO and for the rarely studied molecule HC3N. We report rotational temperatures, production rates, and mixing ratios (relative to H2O as well as to C2H6). We place our results in context by comparing them with other comets observed at near-IR wavelengths. We also compare our results with those obtained using the NIRSPEC-2 spectrograph on Keck II on UT December 17 and 18 and with results obtained from iSHELL on other dates during the same apparition. Within 1–2σ uncertainty, production rates obtained for all molecules in this work were consistent with those obtained using NIRSPEC-2 except H2O, indicating low-level variability on a timescale of days. Mixing ratios with respect to H2O in 46P/Wirtanen were consistent with corresponding values from NIRSPEC-2 within the uncertainty with the exception of CH3OH, which yielded a higher ratio on December 21. Our measurements afforded a high temporal resolution that spanned ∼2/3 of the rotational period of 46P/Wirtanen, enabling us to test short-term variability in the production rates of H2O and HCN due to rotational effects. Both H2O and HCN production rates showed similar temporal variability, resulting in nearly constant HCN/H2O.
Remote Inspection of a FPSO Unit Crude Oil Tank whilst still Producing
Authors: Comley Andrew , Ross Campbell , Moir Steve 
Published: February 2021

In 2020, with the unit still producing a crude oil storage tank on the Bumi Armada owned and operated Armada Kraken FPSO was successfully inspected by Texo using a UAVS flown from outside the tank. This type of truly remote survey significantly reduces the risk to personnel, the survey time and the survey cost, whilst maintaining a survey standard that is close to that achieved by personnel entering the tank and utilising scaffolding.

Lessons learnt in the following areas are discussed:
•	Detailed Scope of Work value, including potential & actual anomaly handling.
•	Careful pre-mobilisation briefing of the project team and Class surveyor.
•	Engagement with Bumi Armada personnel, onshore and offshore, and the Texo project team.
•	Engagement with DNVGL to enable the inspection to be Verification & Class credited.
•	Development by Texo of project specific procedures based on onshore trials.
•	Tank cleanliness and cleaning.
Quelle place institutionnelle pour l’authenticité ?
Authors: Richet Bertrand 
Published: February 2021

Nous nous proposons d’explorer les singularités de l’authenticité, éclairées par les textes officiels et par l’expérience des quelque 300 visites effectuées depuis 2013 dans les classes, de la 6e à la Khâgne, dans des lycées généraux et technologiques et des lycées professionnels (dont les sections internationales), en métropole et en outre-mer. Partout, les questions qui se posent, en deçà et au-delà de l’exactitude des réalisations phonologiques, lexicales et grammaticales, sont celles du statut des discours, de leur contextualisation, de leur exploitation fondatrice, qui est de nature à éclairer un sens qui se construit et se déconstruit en s’incarnant, mais aussi en se comparant, en se transformant. Par-delà le fétichisme d’un modèle unique, ce qui n’empêche aucunement l’exigence, c’est la somme des regards croisés qui contribue à mettre la langue en relief et les discours en perspective.