bluuebunny/crossref_metadata_2025_split huggingface dataset:
ПРОБЛЕМИ ВПЛИВУ ДИГІТАЛІЗАЦІЇ СУСПІЛЬСТВА НА ВИЩУ ЛІНГВІСТИЧНУ ОСВІТУ ТА НАВЧАЛЬНОГО ПОТЕНЦІАЛУ ЦИФРОВИХ ТЕХНОЛОГІЙ У БАГАТОМОВНІЙ ПІДГОТОВЦІ СТУДЕНТІВ ЗАКЛАДІВ ВИЩОЇ ОСВІТИ
Authors: Нікітіна Наталія 
Published: December 2021

У статті досліджується вплив дигіталізації суспільства на лінгвістичну освіту та визначається освітній потенціал цифрових технологій у багатомовній підготовці студентів закладів вищої освіти. Надзвичайно важливі для держави роль та місце дигіталізації освіти в багатомовному середовищі посилюються націоналізацією країни з метою концептуалізації національних інтересів країни.
Різні аспекти впровадження дигіталізації в освітній простір стали предметом вивчення іноземних (С. Бассетт, Ч. Гір, Г. Грібер, М. Деузе, Г. Грібер та Р. Мартін, Л. Ванович, Дж. Стоммель, М. Хенд) та вітчизняних (В. Биков, Д. Галкін, М. Жалдак, М. Лещенко, П. Матюшко, О. Овчарук, В. Ребрина, О. Стрижак, М. Шишкіна, А. Яцишин) вчених. Однак, незважаючи на зацікавленість наукового співтовариства, питання впровадження цифрових технологій в сучасний освітній простір для реалізації ключових компетенцій, зокрема, майбутніх учителів іноземних мов, все ще потребують більш детального вивчення.
Метою статті є вивчення ключових напрямків впливу дигіталізації суспільства на вищу лінгвістичну освіту та визначення освітнього потенціалу цифрових технологій у багатомовній підготовці студентів університету.
Автор доводить, що використання інноваційних освітніх технологій сприяє вдосконаленню системи моніторингу та оцінювання студентів, індивідуалізації навчального процесу та формуванню вільного доступу до численних електронних ресурсів. Аналіз сучасних педагогічних студій та документальної бази дозволив констатувати, що використання цифрових технологій у багатомовній підготовці студентів закладів вищої освіти забезпечує ефективне формування іншомовних комунікативних компетенцій; передбачає використання сучасних психолого-педагогічних та інформаційно-комунікаційних технологій; дає можливість постійного зворотного зв’язку для студентів. Дигіталізація робить навчальний процес більш персоналізованим, доступним та гнучким. Це, у свою чергу, створює комфортні умови для самостійного навчання, ефективного розвитку та кар’єрного зростання.
La Gestión Educativa como compromiso ético en la potencialización de procesos de hermandad y comunidad profesional en la sociedad compleja
Authors: Jaén Vega Omar 
Published: December 2021

Este ensayo pretende ser un aporte como un producto vital de la experiencia de la Maestría en Administración Educativa de la Universidad de La Salle en Costa Rica, promoción 2021. Se exponen sentires y emociones fundamentadas desde la reflexión y el compartir de autores estudiados que han brindado, en cada curso, una mirada y accionar diferente en torno a la Educación. También, se incluyen críticas, aportes personales, reflexiones, experiencias, preguntas y comentarios de autores como: Morin, Assman, Maturana, Capra, De Sousa, Boff, Gutiérrez, Schiavo, papa Francisco, entre otros. Se analiza la importancia del compromiso ético del docente, en función directiva, para la potencialización de procesos de hermandad y comunidad profesional en el contexto de la sociedad compleja.
ANALISIS PENERIMAAN KARYAWAN PADA PT. SRIKANDI DIAMOND INDAH MOTORS SAMPIT DENGAN METODE ANALITYCAL HIERARCHY PROCESS (AHP) DAN SIMPLE ADDITIVE WEIGHTING (SAW)
Authors: Saputra Meidy , Bachtiar Lukman 
Published: December 2021

Pada penelitian ini bertujuan untuk membangun sebuah sistem pendukung keputusan penerimaan karyawan pada PT. Srikandi Diamond Indah Motors. Hampir semua perusahaan mulai dari skala kecil maupun skala besar dalam melakukan kegiatan penerimaan karyawan mulai membuat keputusan dengan menggunakan metode sistem pendukung keputusan untuk menunjang kinerja perusahaannya. Dengan menggunakan sistem pendukung keputusan dalam perekrutan karyawan perusahaan akan lebih selektif lagi dalam memilih calon karyawan yang berkualitas guna menunjang kinerja dalam perusahaan tersebut. PT. Srikandi Diamond Indah Motors adalah salah satu perusahaan yang bergerak pada bidang otomotif. Dari pihak perusahaan tidak ada menerapkan suatu sistem untuk menunjang sebuah keputusan yang terkomputerisasi dalam melakukan seleksi penerimaan karyawan, penilaian pada saat interview calon karyawan masih dengan tulis tangan pada berkas pelamar dan juga dihadapkan pada pilihan untuk menentukan karyawan yang sesuai dengan kriteria perusahaan. Maka dari itu diperlukan sebuah sistem pendukung keputusan yang menerapkan metode Analytical Hierarchy proccess (AHP) dan Simple Additive Weighting (SAW). Hasil penelitian ini sistem pendukung keputusan penerimaan karyawan baru menggunakan metode AHP dan SAW pada PT. Srikandi Diamond Indah Motors diharapkan dapat membantu dan mempercepat dalam proses seleksi penerimaan karyawan. Tujuan menggunakan dua metode ini adalah untuk membandingan hasil perhitungan antara metode AHP dan SAW. Berdasarkan hasil pengujian sistem dan perhitungan berjalan dengan baik dan mendapatkan hasil yang sesuai, akan tetapi lebih direkomendasikan mengambil hasil perhitungan metode AHP karena perhitungan AHP lebih kompleks dibandingan dengan metode SAW.
Melatonin, tunneling nanotubes and anastasis: Cheating cell death
Authors: Reiter Russel J , Sharma Ramaswamy , Rosales-Corral Sergio 
Published: December 2021

When healthy neurons are exposed to toxins or physiological insults such as ischemia, apoptosis is often initiated. Once underway, this mechanistically-well described process was thought to routinely run its course with the disintegration of the cell and phagocytosis of the debris. Within the last decade, the consistency of this process has been questioned. It is now known that some damaged cells can recover, i.e., they avoid death; this restoration process is referred to as anastasis. The reestablishment of a healthy cell phenotype is highly energy-requiring, so optimally functioning mitochondria are obviously beneficial during the regenerative process. Some healthy mitochondria that end up in regenerating cells are transferred there by adjacent healthier cells through tunneling nanotubes. Tunneling nanotubes generally form under stressful conditions when these micron-size tubules link adjacent cells. These tubules transfer soluble factors and organelles, including mitochondria, between the connected cells. When damaged cells receive high APT-producing mitochondria via this means, they support the ability of the cells to recover. Two recent comprehensive publications show that melatonin aids the transfer of mitochondria through nanotubes that connect neurons thereby likely assisting the recovery of the damaged recipient cell. Thus, melatonin not only protects normal neurons from damage by neutralizing the agents that initiate apoptosis, e.g., free radicals, etc., but also reverses this process once it is underway.
Effect of maternal intrinsic factors on productivity and efficiency at weaning in commercial flock of Pelibuey ewes in the tropic of Tabasco, Mexico
Authors: Chay-Canul Alfonso , Ramon-Ugalde Julio , Arcos-Álvarez Darwin N. , Zamora-Bustillos Roberto , Garcia-Herrera Ricardo A. , Macias-Cruz Ulises , Piñeiro-Vazquez Angel T. 
Published: December 2021

Evaluation of ewe efficiency or productivity is a complex trait because of several factors that are related to produce heavy litters (lamb growth traits) per ewe. The objective of present study was to evaluate maternal intrinsic effects (body weight, body condition score, udder type, litter size, lamb sex) on litter growth traits (litter weight at lambing [LBW] and at weaning adjusted for 70 days [LWW70]) as a criteria of productivity and some indexes of efficiency in Pelibuey ewes. Data of body weight (BW), body condition scores (BCS), and udder types (UT) were taken at lambing, likewise at weaning BW (WBW), on 48 multiparous Pelibuey ewes. Additionally, litter size, sex, birth and weaning weight, were recorded for each offspring; this information was used to calculate LBW, LWW70, average daily gain (ADG), and the following indexes: Ewe efficiency (EEF) expressed as kg of lamb weaned per kg ewe BW at lambing, EEF0.75 expressed as kg of lamb weaned per kg ewe metabolic BW (BW0.75) at lambing, and EEF2 expressed as kg of lamb weaned ± ewe BW gained or lost at waning per kg ewe BW at lambing. For statistical analysis, ewes were classified according to BW (low, medium and high), BCS (low and high) and udder type (I, II, III and IV) at lambing. High BW ewes had greater (P? 0.01) LLW and LWW70 than low BW ewes. Ewe BW at lambing did not affect (P> 0.05) any productivity index. Also, BCS from lambed ewes did not alter (P> 0.05) the productivity parameters. The udder type affected only LWW70 and productivity indexes, being similar among ewes with type-I, II and III udders, but lower in ewes with type-IV udders. Likewise, double litters were heavier at birth and weaning than single litters, affecting EEF and EEF0.75, but not EEF. The Pelibuey ewe’s productivity in humid tropic depends on the maternal BW, udder type at lambing and prolificacy, being a better productivity when ewes have a high BW, double lambing and non-misshapen udders.
Intrinsic and Extrinsic Value in Erin Brockovich Movie Script
Authors: Lissamustika Nurfatimah , Putra Ansor , Arman Arman 
Published: December 2021

This study focused on analyzing intrinsic and extrinsic value in “Erin Brockovich” by Susanah Grant. This study aimed to describe a character's utterance that contains intrinsic and extrinsic values in Erin Brockovich's movie script. There are two sources of data in this study, they are movie scripts from Erin Brockovich's movie as primary data and audiovisual movies as secondary data. Data is collected through Searching and downloading the movie script of Erin Brockovich, reading the script, looking for sentences containing the intrinsic and extrinsic value, taking note of Intrinsic value and extrinsic value, coding the data and rechecking the data. Techniques of Data analysis are done through the presentation of data, explaining and interpreting data, and concluding data. This study indicated that the Erin Brockovich movie script has two values as intrinsic and extrinsic value. First, the intrinsic value is presented in the form of Erin's care to the people at Hinkley. Second, the extrinsic value is presented in the form of PG&E's selfish attitude towards the people at Hinckley. The writer obtained 21 data. 18 intrinsic value data and 3 extrinsic data of intrinsic value found in this movie script meaning that intrinsic value is more dominant than extrinsic value. Intrinsic value is more dominant than the extrinsic value because in this movie script the focus is more on discussing positive actions carried out by the characters in the movie that are helping people by overcoming cases of water pollution.
The Flouting and Violating Maxims In Deadpool 2 Movie Script
Authors: Safitri Rismayanti , Martisa Ela 
Published: December 2021

This current study is aiming to find out the flouting and violating of maxims produced by characters in Deadpool 2 movie. The theory uses in this study is theory of Grice about maxims . Descriptive qualitative method is used to analyze the data. Steps in analyzing the data consist of presenting the data, describing the context of the data, interpreting the data and making the conclusion. Based on the research, It found that there are four types of flouting and violating the Grice’s maxims which derived from 22 data. 15 data that flouted the Grice’s maxims, they are 1 data flouting maxim of quantity, 6 data flouting maxim of quality, 1data flouting maxim of relation, and 7 data flouting maxim of manner. 7 data that violated the Grice’s maxims, they are 1 violating maxim of quantity, 1 violating maxim of quality, 3 violating maxim of relation, and 2 violating maxim of manner. Flouting maxim of manner becomes the most dominant types of flouting maxim, and violating maxim of relation becomes the most dominant types of violating maxim in the movie.
Prevalencia y caracterización de mujeres vírgenes con diagnóstico de cáncer de cérvix, endometrio y ovario, un estudio de centro único
Authors: Granda Maldonado Doménica Romina , Vicuña Freire Fernando Humberto , Landivar Varas Xavier Francisco 
Published: December 2021

Introducción: El cáncer de endometrio, el cáncer de ovario y el cáncer cervicouterino son las neoplasias, dentro del cáncer del aparato reproductor femenino, que se consideran más frecuentes en la actualidad. La aparición de cáncer ginecológico en mujeres vírgenes demuestra que se deben consideran otras factores causales de la enfermedad, sin embargo, en nuestro país, no hay la suficiente evidencia de documentación sobre estos casos. El objetivo del presente estudio medir la prevalencia de cáncer de cuello uterino, útero y ovarios en mujeres vírgenes atendidas en un centro de referencia de Ginecología Oncológica de Guayaquil.
Metodología: El estudio es observacional y transversal, se realizó en el Hospital de Especialidades Teodoro Maldonado Carbo, del Instituto Ecuatoriano de Seguridad Social, Guayaquil-Ecuador, de enero del 2013 al diciembre del 2017. Se incluyeron pacientes con cáncer cervicouterino, de útero y ovarios divididos en Grupo 1 (G1) Mujeres vírgenes y Grupo 2 (G2): Mujeres con vida sexual activa. Las variables fueron edad, órgano afectado, comorbilidades, antecedente familiar de cáncer, tipo histológico y muerte. La muestra fue no probabilística, tipo censo. Se utiliza estadística analítica, la muestra dividida en 2 grupos se compara usando Chi2. Se reporta Odds Ratio con intervalo de confianza del 95%.
Resultados: En G1 fueron 44 casos y en G2 fueron 337 casos. Lo que representa una prevalencia de 11.55% (IC95% 11.38-11.71%). Cáncer de Ovario en G1 fue 29/44 casos (66%) versus 95/337 casos (28.2%) en G2 P<0.0001 con OR: 4.92 (2.53-9.60). Cáncer de endometrio en G1 13/44 casos (29.5%) versus 54/337 casos (16%) en G2, OR 2.20 (1.08-4.47) P=0.03. Cáncer cervical en G1 2/44 casos (4.5%) y en G2 188/337 casos (55.8%) OR 0.38 (0.009-0.159) P<0.0001. La mortalidad en G1 fue 30/44 casos en G2 fue 130/337 casos, OR 4.14 (2.12-8.08) P>0.0001.
Conclusión: En mujeres sin antecedentes de vida sexual, existe mayor riesgo de cáncer de ovario y de en-dometrio y el riesgo de cáncer de cérvix se disminuye un 96%. La mortalidad de este grupo de mujeres se duplica por la mayor existencia de cáncer de ovario y endometrial.
Expression Profiles of Circular RNA in Aortic Vascular Tissues of Spontaneously Hypertensive Rats
Authors: Liu Ying , Dong Ying , Dong Zhaojie , Song Jiawei , Zhang Zhenzhou , Liang Lirong , Liu Xiaoyan , Sun Lanlan , Li Xueting , Zhang Miwen , Chen Yihang , Miao Ran , Zhong Jiuchang 
Published: December 2021

Background: Circular RNAs (circRNAs), as a kind of endogenous non-coding RNA, have been implicated in ischemic heart diseases and vascular diseases. Based on theirs high stability with a closed loop structure, circRNAs function as a sponge and bind specific miRNAs to exert inhibitory effects in heart and vasculature, thereby regulating their target gene and protein expression, via competitive endogenous RNA (ceRNA) mechanism. However, the exact roles and underlying mechanisms of circRNAs in hypertension and related cardiovascular diseases remain largely unknown.Methods and Results: High-throughput RNA sequencing (RNA-seq) was used to analyze the differentially expressed (DE) circRNAs in aortic vascular tissues of spontaneously hypertensive rats (SHR). Compared with the Wistar-Kyoto (WKY) rats, there were marked increases in the levels of systolic blood pressure, diastolic blood pressure and mean blood pressure in SHR under awake conditions via the tail-cuff methodology. Totally, compared with WKY rats, 485 DE circRNAs were found in aortic vascular tissues of SHR with 279 up-regulated circRNAs and 206 down-regulated circRNAs. Furthermore, circRNA-target microRNAs (miRNAs) and the target messenger RNAs (mRNAs) of miRNAs were predicted by the miRanda and Targetscan softwares, respectively. Additionally, real-time RT-PCR analysis verified that downregulation of rno_circRNA_0009197, and upregulation of rno_circRNA_0005818, rno_circRNA_0005304, rno_circRNA_0005506, and rno_circRNA_0009301 were observed in aorta of SHR when compared with that of WKY rats. Then, the potential ceRNA regulatory mechanism was constructed via integrating 5 validated circRNAs, 31 predicted miRNAs, and 266 target mRNAs. More importantly, three hub genes (NOTCH1, FOXO3, and STAT3) were recognized according to PPI network and three promising circRNA-miRNA-mRNA regulatory axes were found in hypertensive rat aorta, including rno_circRNA_0005818/miR-615/NOTCH1, rno_circRNA_0009197/ miR-509-5p/FOXO3, and rno_circRNA_0005818/miR-10b-5p/STAT3, respectively.Conclusions: Our results demonstrated for the first time that circRNAs are expressed aberrantly in aortic vascular tissues of hypertensive rats and may serve as a sponge linking with relevant miRNAs participating in pathogenesis of hypertension and related ischemic heart diseases via the circRNA-miRNA-mRNA ceRNAnetwork mechanism.
Bridging Legends and Science: Field Evidence of a Large Tsunami that Affected the Kingdom of Tonga in the 15th Century
Authors: Lavigne Franck , Morin Julie , Wassmer Patrick , Weller Olivier , Kula Taaniela , Maea Ana V. , Kelfoun Karim , Mokadem Fatima , Paris Raphael , Malawani Mukhamad Ngainul , Faral Audrey , Benbakkar Mhammed , Saulnier-Copard Ségolène , Vidal Céline M. , Tu’I’afitu Tu’I’ahai , Kitekei’aho Fuka , Trautmann Martine , Gomez Christopher 
Published: December 2021

The pre-colonial history (i.e. before the 16th century) of Tonga and West Polynesia still suffers from major gaps despite significant scientific advances in recent years, particularly in the field of archaeology. By the 14th century, the powerful Tu’i Tonga kingdom united the islands of the Tongan archipelago under a centralised authority and, according to tradition, extended its influence to neighbouring island groups in the Central Pacific. However, some periods of deep crisis were identified, e.g. in the mid- 15th century, marked by an abrupt cessation of inter-archipelago migration on the deep seas in the Pacific, significant cultural changes, and a decrease in accessible natural resources. The origins of these disturbances are still debated, and they are usually assigned to internal political problems or loss of external influence vis-à-vis neighboring chiefdoms. However, the hypothesis of a major natural disaster was rarely suggested up to now, while field evidence points to the occurrence of a very large tsunami in the past, including the presence of numerous megablocks that were deposited by a “red wave” (orpeau kula, which also mean tsunami in the Tongan language) according to a local myth. Drawing on a body of new evidence from sedimentary signatures and radiocarbon dating of charcoal and marine bioclasts, geomorphology, and sedimentology, in support of previously published archaeological data, we argue that a large tsunami inundated large areas of Tongatapu island in the mid-15th century with runup heights up to 30 m, and that the Tu’i Tonga kingdom was severely impacted by this event. We also discuss the likely sources of this tsunami.
Clinical Implication of Individually Tailored Segmentation Method for Distorted Hypothalamus in Craniopharyngioma
Authors: Hong A Ram , Lee Miwoo , Lee Jung Hyun , Kim Jung Hee , Kim Yong Hwy , Choi Hyung Jin 
Published: December 2021

ObjectiveSeveral attempts have been done to capture damaged hypothalamus (HT) using volumetric measurements to predict the development of hypothalamic obesity in patients with craniopharyngioma (CP). This study was to develop a novel method of HT volume measurement and examine the associations between postoperative HT volume and clinical parameters in patients with CP.MethodsWe included 78 patients with adult-onset CP who underwent surgical resection. Postoperative HT volume was measured using T1- and T2-weighted magnetic resonance imaging (MRI) with a slice thickness of 3 mm, and corrected for temporal lobe volume. We collected data on pre- and postoperative body weights, which were measured at the time of HT volume measurements.ResultsThe corrected postoperative HT volume measured using T1- and T2-weighted images was significantly correlated (r=0.51 [95% confidence interval (CI) 0.32 to 0.67], P&lt;0.01). However, HT volume was overestimated using T1-weighted images owing to obscured MR signal of the thalamus in patients with severe HT damage. Therefore, we used T2-weighted images to evaluate its clinical implications in 72 patients with available medical data. Postoperative HT volume was negatively associated with preoperative body weight and preoperative tumor volume (r=–0.25 [95% CI -0.45 to -0.04], P=0.04 and r=–0.26 [95% CI -0.40 to -0.15], P=0.03, respectively). In the subgroup analysis of CP patients who underwent primary surgery (n=56), pre- and postoperative body weights were negatively associated with HT volume (r=–0.30 [95% CI -0.53 to -0.03], P=0.03 and r=–0.29 [95% CI -0.53 to -0.02], P=0.03, respectively).ConclusionsAdult-onset CP patients showed negative associations between postoperative HT volume and preoperative/postoperative body weight using a new method of HT volume measurement based on T2-weighted images.
Ambulatory Endoscopic Thyroidectomy via a Chest-Breast Approach Has an Acceptable Safety Profile for Thyroid Nodule
Authors: Zhang Zeyu , Xia Fada , Li Xinying 
Published: December 2021

IntroductionWith the growing esthetic requirements, endoscopic thyroidectomy develops rapidly and is widely accepted by practitioners and patients to avoid the neck scar caused by open thyroidectomy. Although ambulatory open thyroidectomy is adopted by multiple medical centers, the safety and potential of ambulatory endoscopic thyroidectomy via a chest-breast approach (ETCBA) is poorly investigated.Material and MethodsPatients with thyroid nodules who received conventional or ambulatory ETCBA at Xiangya hospital, Central South University from January 2017 to June 2020 were retrospectively included. The incidence of postoperative complications, 30-days readmission rate, financial cost, duration of hospitalization, mental health were mainly investigated.ResultsA total of 260 patients were included with 206 (79.2%) suffering from thyroid carcinoma, while 159 of 260 received ambulatory ETCBA. There was no statistically significant difference in the incidence of postoperative complications (P=0.249) or 30-days readmission rate (P=1.000). In addition, The mean economic cost of the ambulatory group had a 29.5% reduction compared with the conventional group (P&lt;0.001). Meanwhile, the duration of hospitalization of the ambulatory group was also significantly shorter than the conventional group (P&lt;0.001). Patients received ambulatory ETCBA showed a higher level of anxiety (P=0.041) and stress (P=0.016). Subgroup analyses showed consistent results among patients with thyroid cancer with a 12.9% higher complication incidence than the conventional ETCBA (P=0.068).ConclusionAmbulatory ETCBA is as safe as conventional ETCBA for selective patients with thyroid nodules or thyroid cancer, however with significant economic benefits and shorter duration of hospitalization. Extra attention should be paid to manage the anxiety and stress of patients who received ambulatory ETCBA.