bluuebunny/crossref_metadata_2025_split huggingface dataset:
XII Scientific Technical Conference On Low Temperature Plasma During The Deposition Of Functional Coatings
Authors: Kashapov N F , Luchkin A G 
Published: June 2021

Abstract
In the city of Kazan from November 10 to November 12, 2020 on the basis of the Kazan Federal University hosted the XII Scientific Technical Conference on Low Temperature Plasma during the Deposition of Functional Coatings.
One of the main tasks of the conference is to discuss and develop the fundamental principles of plasma deposition of functional coatings. Conference papers were presented in the following areas:
– Physics of gas discharge;
– Physical processes in low-temperature plasma when applying functional coatings;
– Thermodynamic, portable and optical properties of low-temperature plasma in coating processes;
– Interaction of plasma and high-energy ion beams with a solid;
– Combustion processes and heat and mass transfer in multiphase media;
– Dusty plasma;
– Plasma chemistry. Electrochemistry;
– Diagnostics of low-temperature plasma;
– Characteristics of coatings obtained using low-temperature plasma;
– Application of ion-plasma coatings.
Within the framework of the conference, a school for young scientists is held, lectures by leading scientists and specialists in the field of low-temperature plasma application are held.
Gas-discharge plasma is widely used in various fields of science and technology. Plasma is used in industry, medicine, ecology and is the basis of various devices and technologies, for example, it is used in the technology of applying functional coatings.
The friendly atmosphere at the XII Scientific Technical Conference on Low Temperature Plasma during the Deposition of Functional Coatings allowed it to become an excellent platform for the exchange of experience and generation of new ideas in the field of physics and the use of low-temperature plasma.
List of Organizing Committee are available in this pdf.
Study of physical and mechanical properties of steel after plasma modification of its surface
Authors: Kh Gadzhiev M , Tereshonok D V , Sargsyan M A , Ilichev M V , Son E E 
Published: June 2021

Abstract
On the basis of studies of the electrophysical characteristics of a low-temperature nitrogen plasma flow, a procedure for verifying the thermophysical properties and establishing regularities in the formation of the structure, phase composition, and properties of a metal when steels surface is exposed to plasma, plasma exposure modes were determined for modifying the surface of metals and alloys used in various applications, such as nuclear power plants.
Study of the cathode spot on a liquid electrolyte by using highspeed visualization and software of coloured images processing
Authors: Tazmeev B K , Tsybulevsky V V , Tazmeeva R N , Tazmeev G K 
Published: June 2021

Abstract
The processing of coloured images of concentration area of cathode spots, obtained as a result of high-speed visualization of gas discharge with a liquid electrolyte cathode, was performed. The polygon functions of empirical distribution for intensity code of color were constructed. A correlation was found between the radiation intensity and small-scale current pulsations.
About the conditions of volumetric combustion of the gas discharge with water-solution cathode in an extended discharge gap at atmospheric pressure
Authors: Tazmeev K K , Tazmeev G K 
Published: June 2021

Abstract
A gas discharge between liquid electrolyte cathode and copper anode was studied experimentally. Water solutions of sodium chloride were used as liquid electrolyte. The discharge was ignited in an open air atmosphere in the current range of 2-5 A at distances of 3-18 cm between the electrodes. The conditions for the formation of volumetric plasma column in discharge gap were revealed.
Thermodynamic combustion analysis of methane-hydrogen and methane-propane-butane mixture in a water heating installation
Authors: Nazarychev S A , Larionov V M , Malahov A O , Larionova I V 
Published: June 2021

Abstract
In this research considers the combustion of methane mixtures with hydrogen or propane-butane fuel as applied to water heating installation. The determination of conditions under which the considered mixtures have a stoichiometric composition, and the heat release rate is equal to the value that corresponds to the combustion of only methane. It is shown that the air consumption is equal in all cases. It has been established how it is necessary to change the fuel consumption depending on the concentration of gases in a mixture with methane in order to implement these conditions.
Acoustic oscillations of the gas with axial distribution of average temperature in the vortex combustion chamber
Authors: Malakhov A O , Larionov V M , Khalilov A R , Fadeev S A , Iovleva O V 
Published: June 2021

Abstract
Modern research of combustion processes affect a large number of combustion modes of gaseous fuel, but so far the effects associated with the occurrence of acoustic oscillations of the gas with a longitudinal temperature distribution have not been well considered. This article discusses the case of the occurrence of self-oscillations in a vortex combustion chamber.
Calculations of electro contact baking of steel powders
Authors: Sakhapov R L , Makhmutov M M , Sultanov V A 
Published: June 2021

Abstract
This paper discusses the use of electro contact baking of steel powder on a bronze bushing. Its main design parameters are: taper angle of the matrix part - α, deg.; internal diameter of the matrix - D, mm; length of the cylindrical deforming belt - L, mm. To prevent melting of the surface of the restored bronze part, a special electrode was used, which made it possible to bake metal powders onto the bronze surface without melting the part to be restored. The diameter of the crimp die is defined as the difference between the outer diameter of the sleeve before compression and the sum of the wear on the inner surface of the bronze sleeve and the allowance for machining to obtain the nominal size of the inner diameter of the sleeve.
Public-private partnership in fighting the COVID-19 global economic lockdown
Authors: Vaslavsky Yan I 
Published: June 2021

Abstract
The COVID-19 pandemic dealt a serious blow to national socio-economic systems, causing the deepest economic crisis since the Great Depression. Neither national economies and their states, nor national health and social welfare systems, nor private business, nor the global economy have stood the test of the coronavirus pandemic. The COVID-19 pandemic has predetermined an increase in the area of uncertainty as a new quality of post-coronavirus economic reality, in the structure of which private business plays a decisive role. In this regard, the principles of partnership between the state and private business in the production of public goods need theoretical understanding due to the new reality. Adequate institutionalization of relations between partners in implementing socially significant projects can be an important success factor in the fight against economic lockdown. The state dictate regarding the terms of partnership with private business, prevailing before COVID-19, largely explains the insignificant contribution of public-private partnerships (PPPs) to accelerating GDP growth in the countries of the world. After COVID-19, the priority of the intentions of private investors in organizing socially significant projects with the state should become the norm that will allow using PPPs to unlock the economic lockdown.
Ischemic Placental Disease, Preterm Delivery, and Their Association With Opioid Use During Pregnancy
Authors: Esposito Daina B , Bateman Brian , Werler Martha , Straub Loreen , Mogun Helen , Hernandez-Diaz Sonia , Huybrechts Krista 
Published: June 2021

Abstract
Opioids affect placental development and function in animal models, but human data on their association with ischemic placental disease are limited. Using a cohort of pregnant women in the US nationwide Medicaid Analytic eXtract (2000–2014), we compared women with ≥2 opioid dispensings in pregnancy with unexposed women. Given an uncertain etiologically relevant window, we assessed exposure occurring in early pregnancy, late and not early pregnancy, and both early and late pregnancy. For placental abruption, preterm delivery, small for gestational age (SGA), and preeclampsia, we estimated adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) using Cox proportional hazard models adjusting for demographic factors, indications/comorbidities, and medications. Among 1,833,871 eligible pregnancies, ≥2 opioid dispensings were filled in 6.5%. We observed an early exposure aHR of 1.34 (95% CI: 1.26, 1.43) for placental abruption, 1.21 (95% CI: 1.18, 1.23) for preterm delivery, 1.13 (95% CI: 1.09, 1.17) for SGA, and 0.95 (0.91, 0.98) for preeclampsia. Estimates for late exposure were attenuated. Early and late exposure was associated with higher aHRs for placental abruption, 1.62 (95% CI: 1.47, 1.78); preterm delivery, 1.37 (95% CI: 1.33, 1.42); and SGA, 1.26 (95% CI: 1.19, 1.33); but not preeclampsia, 0.99 (95% CI: 0.93, 1.05). Prescription opioids may modestly increase risk of placental abruption, preterm birth and SGA, but they do not appear to be associated with preeclampsia.
A novel graph attention model for predicting frequencies of drug–side effects from multi-view data
Authors: Zhao Haochen , Zheng Kai , Li Yaohang , Wang Jianxin 
Published: June 2021

Abstract
Identifying the frequencies of the drug–side effects is a very important issue in pharmacological studies and drug risk–benefit. However, designing clinical trials to determine the frequencies is usually time consuming and expensive, and most existing methods can only predict the drug–side effect existence or associations, not their frequencies. Inspired by the recent progress of graph neural networks in the recommended system, we develop a novel prediction model for drug–side effect frequencies, using a graph attention network to integrate three different types of features, including the similarity information, known drug–side effect frequency information and word embeddings. In comparison, the few available studies focusing on frequency prediction use only the known drug–side effect frequency scores. One novel approach used in this work first decomposes the feature types in drug–side effect graph to extract different view representation vectors based on three different type features, and then recombines these latent view vectors automatically to obtain unified embeddings for prediction. The proposed method demonstrates high effectiveness in 10-fold cross-validation. The computational results show that the proposed method achieves the best performance in the benchmark dataset, outperforming the state-of-the-art matrix decomposition model. In addition, some ablation experiments and visual analyses are also supplied to illustrate the usefulness of our method for the prediction of the drug–side effect frequencies. The codes of MGPred are available at https://github.com/zhc940702/MGPred and https://zenodo.org/record/4449613.
Tracking the pipeline: immunoinformatics and the COVID-19 vaccine design
Authors: Rezaei Shokouh , Sefidbakht Yahya , Uskoković Vuk 
Published: June 2021

AbstractWith the onset of the COVID-19 pandemic, the amount of data on genomic and proteomic sequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stored in various databases has exponentially grown. A large volume of these data has led to the production of equally immense sets of immunological data, which require rigorous computational approaches to sort through and make sense of. Immunoinformatics has emerged in the recent decades as a field capable of offering this approach by bridging experimental and theoretical immunology with state-of-the-art computational tools. Here, we discuss how immunoinformatics can assist in the development of high-performance vaccines and drug discovery needed to curb the spread of SARS-CoV-2. Immunoinformatics can provide a set of computational tools to extract meaningful connections from the large sets of COVID-19 patient data, which can be implemented in the design of effective vaccines. With this in mind, we represent a pipeline to identify the role of immunoinformatics in COVID-19 treatment and vaccine development. In this process, a number of free databases of protein sequences, structures and mutations are introduced, along with docking web servers for assessing the interaction between antibodies and the SARS-CoV-2 spike protein segments as most commonly considered antigens in vaccine design.
Iodoacetic acid affects estrous cyclicity, ovarian gene expression, and hormone levels in mice
Authors: Gonsioroski Andressa , Meling Daryl D , Gao Liying , Plewa Michael J , Flaws Jodi A 
Published: June 2021

Abstract
Iodoacetic acid (IAA) is a water disinfection byproduct that is an ovarian toxicant in vitro. However, information on the effects of IAA on ovarian function in vivo was limited. Thus, we determined whether IAA exposure affects estrous cyclicity, steroidogenesis, and ovarian gene expression in mice. Adult CD-1 mice were dosed with water or IAA (0.5–500 mg/L) in the drinking water for 35–40 days during which estrous cyclicity was monitored for 14 days. Ovaries were analyzed for expression of apoptotic factors, cell cycle regulators, steroidogenic factors, estrogen receptors, oxidative stress markers, and a proliferation marker. Sera were collected to measure pregnenolone, androstenedione, testosterone, estradiol, inhibin B, and follicle-stimulating hormone (FSH) levels. IAA exposure decreased the time that the mice spent in proestrus compared to control. IAA exposure decreased expression of the proapoptotic factor Bok and the cell cycle regulator Ccnd2 compared to control. IAA exposure increased expression of the proapoptotic factors Bax and Aimf1, the antiapoptotic factor Bcl2l10, the cell cycle regulators Ccna2, Ccnb1, Ccne1, and Cdk4, and estrogen receptor Esr1 compared to control. IAA exposure decreased expression of Sod1 and increased expression of Cat, Gpx and Nrf2. IAA exposure did not affect expression of Star, Cyp11a1, Cyp17a1, Hsd17b1, Hsd3b1, Esr2, or Ki67 compared to control. IAA exposure decreased estradiol levels, but did not alter other hormone levels compared to control. In conclusion, IAA exposure alters estrous cyclicity, ovarian gene expression, and estradiol levels in mice.
Non-coding RNAs in cardiac inflammation: key drivers in the pathophysiology of heart failure
Authors: Sansonetti Marida , De Windt Leon J 
Published: June 2021

AbstractHeart failure is among the most progressive diseases and a leading cause of morbidity. Despite several advances in cardiovascular therapies, pharmacological treatments are limited to relieve symptoms without curing cardiac injury. Multiple observations point to the involvement of immune cells as key drivers in the pathophysiology of heart failure. In particular, there is a growing recognition that heart failure is related to a prolonged and insufficiently repressed inflammatory response leading to molecular, cellular, and functional cardiac alterations. Over the last decades, non-coding RNAs are recognized as prominent mediators of cardiac inflammation, affecting the function of several immune cells. In the current review, we explore the contribution of the diverse immune cells in the progression of heart failure, revealing mechanistic functions for non-coding RNAs in cardiac immune cells as a new and exciting field of investigation.
Effectiveness and Safety of Adalimumab Biosimilar SB5 in Inflammatory Bowel Disease: Outcomes in Originator to SB5 Switch, Double Biosimilar Switch and Bio-Naïve SB5 Observational Cohorts
Authors: Derikx Lauranne A A P , Dolby Heather W , Plevris Nikolas , Lucaciu Laura , Rees Caitlin S , Lyons Mathew , Siakavellas Spyros I , Constantine-Cooke Nathan , Jenkinson Philip , Su Shanna , O’Hare Claire , Kirckpatrick Laura , Merchant Lynne M , Noble Colin , Arnott Ian D , Jones Gareth-Rhys , Lees Charlie W 
Published: June 2021

AbstractBackground and AimsMultiple adalimumab [ADA] biosimilars are now approved for use in inflammatory bowel disease [IBD]; however, effectiveness and safety data remain scarce. We aimed to investigate long-term outcomes of the ADA biosimilar SB5 in IBD patients following a switch from the ADA originator [SB5-switch cohort] or after start of SB5 [SB5-start cohort].MethodsWe performed an observational cohort study in a tertiary IBD referral centre. All IBD patients treated with Humira underwent an elective switch to SB5. We identified all these patients in a biological prescription database that prospectively registered all ADA start and stop dates including brand names. Data on IBD phenotype, C-reactive protein [CRP], drug persistence, ADA drug and antibody levels, and faecal calprotectin were collected.ResultsIn total, 481 patients were treated with SB5, 256 in the SB5-switch cohort (median follow-up: 13.7 months [IQR 8.6–15.2]) and 225 in the SB5-start cohort [median follow-up: 8.3 months [4.2–12.8]). Of the SB5-switch cohort, 70.8% remained on SB5 beyond 1 year; 90/256 discontinued SB5, mainly due to adverse events [46/90] or secondary loss of response [37/90]. In the SB5-start cohort, 81/225 discontinued SB5, resulting in SB5-drug persistence of 60.3% beyond 1 year. No differences in clinical remission [p = 0.53], CRP [p = 0.80], faecal calprotectin [p = 0.40] and ADA trough levels [p = 0.55] were found between baseline, week 26 and week 52 following switch. Injection site pain was the most frequently reported adverse event.ConclusionSwitching from ADA originator to SB5 appeared effective and safe in this study with over 12 months of follow-up.
Transcriptome-wide identification and characterization of microRNAs in diverse phases of wood formation in Populus trichocarpa
Authors: Wang Ruiqi , Reng Mengxuan , Tian Shuanghui , Liu Cong , Cheng He , Liu Yingying , Zhang Huaxin , Saqib Muhammad , Wei Hairong , Wei Zhigang 
Published: June 2021

Abstract
We applied miRNA expression profiling method to Populus trichocarpa stems of the three developmental stages, primary stem (PS), transitional stem (TS), and secondary stem (SS), to investigate miRNA species and their regulation on lignocellulosic synthesis and related processes. We obtained 892, 872, and 882 known miRNAs and 1727, 1723, and 1597 novel miRNAs, from PS, TS, and SS, respectively. Comparisons of these miRNA species among different developmental stages led to the identification of 114, 306, and 152 differentially expressed miRNAs (DE-miRNAs), which had 921, 2639, and 2042 candidate target genes (CTGs) in the three respective stages of the same order. Correlation analysis revealed 47, 439, and 71 DE-miRNA-CTG pairs of high negative correlation in PS, TS, and SS, respectively. Through biological process analysis, we finally identified 34, 6, and 76 miRNA-CTG pairs from PS, TS, and SS, respectively, and the miRNA target genes in these pairs regulate or participate lignocellulosic biosynthesis-related biological processes: cell division and differentiation, cell wall modification, secondary cell wall biosynthesis, lignification, and programmed cell death processes. This is the first report on an integrated analysis of genome-wide mRNA and miRNA profilings during multiple phases of poplar stem development. Our analysis results imply that individual miRNAs modulate secondary growth and lignocellulosic biosynthesis through regulating transcription factors and lignocellulosic biosynthetic pathway genes, resulting in more dynamic promotion, suppression, or regulatory circuits. This study advanced our understanding of many individual miRNAs and their essential, diversified roles in the dynamic regulation of secondary growth in woody tree species.
Gaps to Address in Ecological Studies of Temperament and Physiology
Authors: McMahon Elyse K , Cavigelli Sonia A 
Published: June 2021

AbstractEcology is a diverse field with many researchers interested in drivers and consequences of variability within populations. Two aspects of variability that have been addressed are behavioral and physiological. While these have been shown to separately influence ecological outcomes such as survival, reproductive success, and fitness, combined they could better predict within-population variability in survival and fitness. Recently there has been a focus on potential fitness outcomes of consistent behavioral traits that are referred to as personality or temperament (e.g., boldness, sociability, and exploration). Given this recent focus, it is an optimal time to identify areas to supplement in this field, particularly in determining the relationship between temperament and physiological traits. To maximize progress, in this perspective paper, we propose that the following two areas be addressed: (1) increased diversity of species and (2) increased number of physiological processes studied, with an eye toward using more representative and relatively consistent measures across studies. We first highlight information that has been gleaned from species that are frequently studied to determine how animal personality relates to physiology and/or survival/fitness. We then shine a spotlight on important taxa that have been understudied and that can contribute meaningful, complementary information to this area of research. And last, we propose a brief array of physiological processes to relate to temperament, and that can significantly impact fitness, and that may be accessible in field studies.
Colonial Lives of the Carceral Archipelago: Rethinking the Neoliberal Security State
Authors: Axster Sabrina , Danewid Ida , Goldstein Asher , Mahmoudi Matt , Tansel Cemal Burak , Wilcox Lauren 
Published: June 2021

AbstractMass incarceration, police brutality, and border controls are part and parcel of the everyday experiences of marginalized and racialized communities across the world. Recent scholarship in international relations, sociology, and geography has examined the prevalence of these coercive practices through the prism of “disciplinary,” “penal,” or “authoritarian” neoliberalism. In this collective discussion, we argue that although this literature has brought to the fore neoliberalism's reliance on state violence, it has yet to interrogate how these carceral measures are linked to previous forms of global racial ordering. To rectify this moment of “colonial unknowing,” the collective discussion draws on decolonial approaches, Indigenous studies, and theories of racial capitalism. It demonstrates that “new” and “neoliberal” forms of domestic control must be situated within the global longue durée of racialized and colonial accumulation by dispossession. By mapping contemporary modes of policing, incarceration, migration control, and surveillance onto earlier forms of racial–colonial subjugation, we argue that countering the violence of neoliberalism requires more than nostalgic appeals for a return to Keynesianism. What is needed is abolition—not just of the carceral archipelago, but of the very system of racial capitalism that produces and depends on these global vectors of organized violence and abandonment.