bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship Between Smoking, Narcissism, and Impulsiveness Among Young Women
Authors: Kertzman Semion , Kagan Alex , Vainder Michael , Lapidus Rina , Weizman Abraham 
Published: December 2021

Abstract
Although the connection between smoking and individual differences has been recently recognized, the relationship between narcissistic personality traits and cigarette smoking has received less attention. The notion that personality traits can be associated with addictive behavior is influential in clinical practice. However, questions remain about specific interactions between smoking and personality characteristics that need empirical support to substantiate this hypothesis. This study thus identifies narcissistic and impulsive personality traits as precursors of smoking in a sample of tattooed individuals. In a cross-sectional study (N = 120), personality traits were assessed in young women (aged 18-35 years) using the Narcissistic Personality Inventory (NPI) and the Barratt Impulsivity Scale (BIS-11). The current study, using the regression analysis, has clearly demonstrated that young women who smoke have different personality characteristics as compared with women who do not smoke.
Umbilical Cord Thrombosis: A Rare but Life-threatening Occurrence
Authors: Tong Long-xia , Xiao Ping , Xie Dan , Wu Lin 
Published: December 2021

Abstract
Background: Thrombosis of umbilical vessels is a rare but life-threatening pregnancy complication. The correct diagnosis and clinical management of umbilical cord thrombosis remain a challenge. This study aimed to evaluate the meaningful clinical manifestations and features of umbilical cord thrombosis and its optimal management options.Methods: This retrospective study analyzed umbilical cord thrombosis cases enrolled from January 1, 2011, to May 31, 2021. Data were collected from medical archives where the diagnoses of all patients were established by histopathology.Results: A total of 66 patients with umbilical cord thrombosis were enrolled, including 20 patients with intrauterine fetal death and 6 with fatal labor induction in the second trimester. The overall incidence of umbilical cord thrombosis was 0.05% (66/123,746), and the incidence increased significantly in the last 2 years, reaching 0.19% in 2021. The chief complaint was decreased fetal movement (25/60) or nonreactive nonstress test (NST) (19/40). In the 20 patients with intrauterine stillbirth, 8 patients had ignored fetal movement and were referred to the hospital because of ultrasound findings of intrauterine stillbirth. Five patients were misdiagnosed with a single umbilical artery on prenatal ultrasound. Twenty patients underwent emergency cesarean section due to decreased fetal movement and unresponsive fetal monitoring; all neonates were alive. The gross examination of the placenta and cord revealed umbilical cord abnormalities in 26 patients (39.4%, 26/66). The pathological examination revealed venous, venous and arterial, and arterial thrombosis in 74.2%, 12.1%, and 13.6% of patients, respectively.Conclusions: The main manifestation of umbilical cord thrombosis was decreased or disappeared fetal movement. The importance of self-counting fetal movement should be emphasized to patients. The abnormalities in the umbilical cord are the main cause of this phenomenon. Focus on counting fetal movements, electronic fetal monitoring, and specific signs during a prenatal ultrasound can help early identification of umbilical cord thrombi. Emergency cesarean section is recommended to reduce the risk of interrupting the umbilical cord blood flow.
De novo variants in Chinese ASD trios reveal distinct genetic basis underlying autism with and without developmental delay
Authors: Wang Jincheng , Yu Juehua , Wang Mengdi , Zhang Lingli , Yang Kan , Du Xiujuan , Wu Jinyu , Wang Xiaoqun , Li Fei , Qiu Zilong 
Published: December 2021

Abstract
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder causing impairments in social communication and stereotypical behaviors, often with developmental delay or intellectual disabilities (DD/ID). Accruing evidence indicates that ASD is highly heritable and genome-wide studies on ASD cohorts have defined numerous genetic contributors. Notably, since most of these studies have been performed with individuals of European and Hispanic ancestries, thus there is a paucity of genetic analyses of ASD in the East Asian population. Here, we performed whole-exome sequencing on 772 Chinese ASD trios, combining with a previous 369 ASD trios, to identify de novo variants in 1141 ASD trios. We found that ASD without DD/ID carried less disruptive de novo variants than ASD with DD/ID. Surprisingly, we found that expression of genes with de novo variants in ASD without DD/ID were enriched in a subtype of human neural progenitor cells. Importantly, some ASD risk genes identified in this study are not present in the current ASD gene database, suggesting that there may be unique genetic contributors to ASD with the East Asian ancestry. We validated one such novel ASD candidate gene – SLC35G1 by showing that mice harboring heterozygous deletion of Slc35g1 exhibited defects in social interaction behaviors. Together, this work nominates novel ASD candidate genes and suggests that genome-wide genetic studies in ASD cohorts of different ancestries are essential to reveal the comprehensive genetic architecture of ASD.
New Records of Neobenedenia Girellae (Hargis, 1955) (Monogenea: Capsalidae) In Marine Ornamental Fish Imported To Yucatan, Mexico
Authors: Paredes-Trujillo Amelia , Vidal-Martínez Victor Manuel , Hernández David , Gonzalez-Solis David , Río-Rodríguez Rodolfo del 
Published: December 2021

Abstract
We detected N. girellae infections in 40 species belonging to 12 families of imported marine ornamental fish from a public aquarium in the Mexican state of Yucatan in January 2018 to December 2020 and carried out their identification to the species level using morphological and molecular analyses. Monogeneans were corroborated morphologically and molecularly using a partial sequence of 28S (region D1–D3) ribosomal DNA and analyzed in a molecular phylogenetic context in combination with data derived from other species of N. girellae available in GenBank. The phylogenetic tree revealed that the specimen found consistently belonged to the N. girellae clade. High infection parameters were detected of N. girellae in the hosts. This identification is relevant to aquarists and aquaculturists in the Gulf of Mexico because N. girellae is considered highly pathogenic in confined fish. Clearly, this work demonstrates that the importation of ornamental fish, coupled with deficient sanitary measures (lack of quarantine areas in distribution centres) contributes to the introduction of parasites and their establishment and dispersal within Mexico.
Interleukin-6 and Granulocyte colony-stimulating factor as predictors of the prognosis of influenza-associated pneumonia
Authors: Zhang Jiaying , Wang Jingxia , Gong Yiwen , Gu Yudan , Xiang Qiangqiang , Tang Ling-Ling 
Published: December 2021

Abstract
Background: Pneumonia is a common complication of influenza and closely related to mortality in influenza patients. The present study examines cytokines as predictors of the prognosis of influenza-associated pneumonia. Methods: This study included 101 inpatients with influenza (64 pneumonia and 37 non-pneumonia patients). 48 cytokines were detected in the serum samples of the patients and the clinical characteristics were analyzed. The correlation between them was analyzed to identify predictive biomarkers for the prognosis of influenza-associated pneumonia.Results: Seventeen patients had poor prognosis and developed pneumonia. Among patients with influenza-associated pneumonia, the levels of 8 cytokines were significantly higher in those who had a poor prognosis: interleukin-6 (IL-6), interferon-γ (IFN-γ), granulocyte colony-stimulating factor (G-CSF), monocyte colony-stimulating factor (M-CSF), monocyte chemoattractant protein-1 (MCP-1), monocyte chemoattractant protein-3, Interleukin-2 receptor subunit alpha and Hepatocyte growth factor. Correlation analysis showed that the IL-6, G-CSF, M-CSF, IFN-γ, and MCP-1 levels had positive correlations with the severity of pneumonia. IL-6 and G-CSF showed a strong and positive correlation with poor prognosis in influenza-associated pneumonia patients. The combined effect of the two cytokines resulted in the largest area (0.926) under the receiver-operating characteristic curve. Conclusion: The results indicate that the probability of poor prognosis in influenza patients with pneumonia is significantly increased. IL-6, G-CSF, M-CSF, IFN-γ, and MCP-1 levels had a positive correlation with the severity of pneumonia. Importantly, IL-6 and G-CSF were identified as significant predictors of the severity of influenza-associated pneumonia.
How can clinicians choose between conflicting and discordant systematic reviews? A replication study of the Jadad algorithm
Authors: Lunny Carole , Thirugnanasampanthar Sai Surabi , Kanji Sal , Ferri Nicola , Pieper Dawid , Whitelaw Sera , Tasmin Sara , Nelson Harrison H. , Reid Emma K. , Zhang Jia He , Kalkat Banveer , Chi Yuan , Abdoulrezzak Reema , Zheng Di Wen , Pangka Lindy R.S. , Sooch Anmol , Kang Kevin T. , Wang Xin Ran , Safavi Parisa , Tricco Andrea C. 
Published: December 2021

Abstract
Introduction: The exponential growth of published SRs (SRs) presents challenges for clinicians seeking to answer clinical questions. In 1997, an algorithm was created by Jadad et al. to choose the best SR across multiple but similar SRs with conflicting results. Our study aims to replicate assessments done by authors using the Jadad algorithm to determine: (i) if we chose the same SR as the authors; and (ii) if we would reach the same results.Methods and Analysis: We searched MEDLINE, Epistemonikos, and Cochrane Database of SRs. We included any study using the Jadad algorithm. We used consensus building strategies to operationalise the algorithm and to ensure a consistent approach to interpretation.Results: We identified 21 studies that used the Jadad algorithm to choose one or more SRs. In 62% (13/21) of cases, we were unable to replicate the Jadad assessment and ultimately chose a different SR than the authors. Overall, 18 out of the 21 (86%) independent Jadad assessments agreed in direction of the findings despite 13 having chosen a different SR.Conclusions: Our results suggest that the Jadad algorithm is not reproducible between users as there are no prescriptive instructions about how to operationalise the algorithm. In the absence of a validated algorithm, we recommend that healthcare providers, policy makers, patients and researchers address conflicts between review findings by choosing the SR(s) with meta-analysis of RCTs that most closely resemble their clinical, public health, or policy question, are the most recent, comprehensive (i.e. in terms of number of included RCTs), and at the lowest risk of bias.
Rhizobium lacunae sp. nov., Isolated From a Freshwater Pond
Authors: Chen Wen-Ming , Yang Che-Chia , Young Chiu-Chung , Lin Shih-Yao , Sheu Shih-Yi 
Published: December 2021

Abstract
Bacterial strain designated CSW-27T was isolated from a freshwater pond in Taiwan. Cells were Gram-stain-negative, aerobic, oxidase-positive, catalase-negative, rod-shaped and motile by flagella. Strain CSW-27T grew at 20-40 oC (optimum, 30-37 oC), at pH 5-9 (optimum, pH 6-7) and in the presence of 0-4% NaCl (optimum, 0%). Phylogenetic analyses based on 16S rRNA gene sequences and an up-to-date bacterial core gene set revealed that strain CSW-27T was affiliated with species in the genus Rhizobium. Analysis of 16S rRNA gene sequences showed that strain CSW-27T had the highest similarity to Rhizobium straminoryzae CC-LY845T (98.5%) followed by Rhizobium capsici CC-SKC2T (96.9%). The average nucleotide identity, average amino acid identity and digital DNA-DNA hybridization values between strain CSW-27T and the closely related Rhizobium species were 73.4-86.5, 66.0-88.8 and 13.3-22.1%, respectively. The principal fatty acid was summed feature 8 (C18:1ω7c and/or C18:1ω6c). The main polar lipids were phosphatidylethanolamine, phosphatidylglycerol, diphosphatidylglycerol, phosphatidylmonomethylethanolamine, phosphatidyldimethylethanolamine, phosphatidylcholine, one uncharacterized aminophospholipid, three uncharacterized aminolipids and two uncharacterized lipids. The predominant polyamine was spermidine. The major isoprenoid quinone was Q-10. Genomic DNA G+C content of strain CSW-27T was 63.3%. These polyphasic taxonomic data indicited that strain CSW-27T should be considered as representing a novel species in the genus Rhizobium, for which the name Rhizobium lacunae sp. nov. is proposed with strain CSW-27T (=BCRC 81244T =LMG 31684T) as the type strain.
2450 MHz Microwave Ablation for Liver Metastases Under 3.0T Wide-bore Magnetic Resonance Guidance: a Pilot Study
Authors: Xu Kaihao , Li Zhaonan , Liu Yiming , Liu Zaoqu , Wang Chaoyan , Jiao Dechao , Han Xinwei 
Published: December 2021

Abstract
Purpose: To investigate the feasibility and effectiveness of 3.0T wide-bore magnetic resonance (MR)-guided microwave ablation (MA) for liver metastases (LM).Patients and methods: From October 2018 to May 2020, 39 patients with 63 LM were treated with 3.0T wide-bore MR-guided 2450 MHz MA therapy. The procedure parameters, technical success, complications, biochemical indexes changes, local tumor response, local tumor progression (LTP) and overall survival were recorded and analyzed.Results: The mean tumor maximum diameter and total procedure time were 3.0 cm and 55.2 min, respectively. Technical success was 100% but 5 cases (12.8%) with grade-1 complications. Alanine transaminase, aspartate transaminase and total bilirubin showed slight a transient increase on day 3 (P<0.05) and returned to normal by day 30 (P>0.05). The complete ablation rate for ≦ 2.5 and >2.5 cm lesions were 100 % and 92.5 %, respectively, during the median followup of 12.0 months, LTP rate was 4.8 % (3/63), and the 6-, 12- and 18-month overall survival were 100%, 92.2%, 76.4% , respectively.Conclusion: 3.0T wide-bore MR-guided MA for LM is a safe and effective approach, especially for small LM.
Phonon Localization in Boron Nitride Nanotubes: Mixing Effect of 10B Isotopes and Vacancies
Authors: Islam Md. Sherajul , Howlader Ashraful Hossain , Zheng Rongkun , Stampfl Catherine , Park Jeongwon , Hashimoto Akihiro 
Published: December 2021

Abstract
We explored the mixing effect of 10B isotopes and boron (B) or nitrogen (N) vacancies on the atomic vibrational properties of (10, 0) single-wall boron nitride nanotubes (BNNT). The forced oscillation technique was employed to evaluate the phonon modes for the entire range (0-100%) of 10B isotopes and atomic vacancy densities ranging from 0 to 30%. With increasing isotope densities, we noticed a blue-shift of the Raman active A1 phonon peak, whereas an increased density of mixed or independent B and N vacancies resulted in the emergence of a new low-frequency peak and the annihilation of the A1 peak in the phonon density-of-states. High-energy optical phonons were localized as a result of both 10B isotopes and the presence of mixing defects. We generated typical mode patterns for different defects to show the phonon localization processes due to the defects. We found an asymmetrical nature of the localization length with increasing 10B isotope content, which corresponds well with the isotope inherited localization length of carbon nanotubes and mono-layer graphene. The localization length falls abruptly with the increase in concentration of both atomic vacancies (B or N) and mixing defects (10B isotope and vacancies). These findings are critical for understanding heat conduction and nanoscopic vibrational investigations like tip-enhanced Raman spectra in BNNT, which can map local phonon energies.
GSK-3β Inhibitor SB216763 Resists Oxidative Stress-Induced Apoptosis in Nucleus Pulposus Cell
Authors: Zhu Kai , Guo Song , Han Guoyi , Qiang Xiancheng , Ma Mengmeng , Xu Qinglei , Zhang Fuheng , Zhang Zhijun , Ci Yandong , Li Shaopeng , Zhu Hanbing , Tang Wenjie , Tan Jun 
Published: December 2021

Abstract
Oxidative stress in the intervertebral disc leads to nucleus pulposus (NP) degeneration by inducing cell apoptosis. However, the molecular mechanisms underlying this process remain unclear. Increasing evidence indicates that GSK-3β is related to cell apoptosis induced by oxidative stress. In this study, we explored whether GSK-3β inhibition protects human NP cell against apoptosis under oxidative stress. Immunofluorescence staining was used to show the expression of GSK-3β in human NP cells (NPCs). Flow cytometry, mitochondrial staining and western blot were used to detect apoptosis of treated NPCs, changes of mitochondrial membrane potential and the expression of mitochondrial apoptosis-related proteins using GSK-3β specific inhibitor SB216763. Coprecipitation was used to demonstrate the interaction between GSK-3β and Bcl-2 in an GSK-3β knockdown in vitro model. We delineated the protective effect of GSK-3β specific inhibitor SB216763 on human NP cell apoptosis induced by oxidative stress in vitro. Further, we showed SB216763 exert the protective effect by preservation of the mitochondrial membrane potential and inhibition of caspase 3/7 activity during oxidative injury. The detailed mechanism underlying the antiapoptotic effect of GSK-3β inhibition was also studied by analyzing mitochondrial apoptosis pathway in vitro. We concluded that the GSK-3β inhibitor SB216763 protected mitochondrial membrane potential to delay nucleus pulposus cell apoptosis by inhibiting the interaction between GSK-3β and Bcl-2 and subsequently reducing Cyto-C release and caspase-3 activation. Together, inhibition of GSK-3β using SB216763 in NP may be a favorable therapeutic strategy to slow intervertebral disc degeneration.
Effect of Processing Parameters On Mechanical Properties of Inconel718 Superalloy Fabricated By Direct Energy Deposit
Authors: Jia Tianhao , Zou Bin , Liu Wenbo , Lei Ting , Ding Hongjian 
Published: December 2021

Abstract
In this study, Inconel718 specimens with good mechanical properties were prepared by direct energy deposit (DED) with different laser processing parameters. The mechanical properties of Inconel718 samples fabricated by laser direct energy deposit method without heat treatment were measured. The fractures and metallographic structures of prepared Inconel718 were observed, and the mechanism of the effect of diverse machining parameters on mechanical properties of Inconel718 was analyzed from the micro level. The results showed the microstructures of depositions of Inconel 718 specimens prepared by DED were compact with fine grains and anisotropic microstructures, where macroscopic defects were barely seen. The mechanical properties and microstructures of Inconel718 were influenced by processing parameters, among which the forming angle and laser power had the most remarkable effect. According to the experimental data, it could be observed that the Inconel718 specimens prepared by DED had the best performance under the circumstance of 1400W laser power, 1.0mm layer thickness, 600mm/min scanning speed, 1.3mm hatch spacing, and 90° forming angle, whose ultimate tensile strength (UTS) and macro hardness were 1016.10MPa and 36.2HRC respectively. The UTS of Inconel 718 manufactured by DED was close to that of Inconel718 prepared by traditional forging, and even it had higher hardness.
Synthesis and Characterization of Antibacterial Viscose Nonwoven Fabric by the Cooperative Action of Se Nanoparticles and Amino Hyperbranched Polymer
Authors: Xiao Yao , Gan Zhenzheng , Dong Erying , Yan Jiawei , Liu Wanwan , Zhang Guangyu 
Published: December 2021

Abstract
This research provides a new method for preparing nanoparticle-coated cellulose fabrics, which has broad application prospects in the functional fiber industry. In this work amino-terminated hyperbranched poly (HBP)-capped Selenium nanoparticles (Se NPs) were synthesized for coating viscose nonwoven fabric (VNF) via impregnation method to produce a controllable and uniform Se NPs coating on the viscose fiber surface. The prepared Se NPs and the treated VNF were characterized by the transmission electron microscope (TEM), x-ray diraction (XRD), x-ray photoelectron spectroscopy (XPS), field emission scanning electron microcopy (FE-SEM), and antibacterial measurement. The results indicate that the Se NPs were spherical shaped with an average size of 10 nm. FESEM, XRD, and XPS characterizations demonstrated that Se NPs can adsorbed and distributed uniformly on the fiber surface. Se NPs-coated VNF showed above 99.9% bacterial reduction of Staphylococcus aureus and Escherichia coli while the Se element content on VNF was about 292 mg/kg.
Associated Factors and Safety of the Rapidly Achieving First Therapeutic Target of Warfarin in hospitalized Patients: A Retrospective Cohort Study
Authors: Yang Wenjun , Ma Jun , Hu Wei , Dai Haibin , Xu Huimin 
Published: December 2021

Abstract
Background

Warfarin is a commonly used anticoagulant drug in clinical practice. Rapidly achieving the first therapeutic international normalized ratio (INR) of warfarin may reduce the hospital length of stay. However, little research has been carried out to evaluate the influencing factors and the safety of rapidly achieving the first therapeutic INR target of warfarin.
Aim

To investigate the associated factors and the safety of rapidly achieving the first therapeutic INR target of warfarin.
Method

A retrospective cohort study was conducted in inpatients who took warfarin from November 2018 to October 2019. Patients’ information was retrieved from medical records.
Results

487 patients were included. The mean achieving first therapeutic target time was 6.0 ± 3.2 days (median, 5.0 days). Age > 65 years, body mass index < 24 kg/m2, and initial warfarin dose ≥ 3 mg/d were independent factors associated with the rapidly achieving first INR target of warfarin therapy. The incidence of INR ≥ 4 was higher in patients achieving the first INR target rapidly than those achieving the first INR target slowly, while there were no significant differences in bleeding events between the two groups.
Conclusion

Hospitalized patients aged > 65 years, with a body mass index < 24 kg/m2, or receiving an initial warfarin dose ≥ 3mg/d were more likely to achieve the first INR target of warfarin rapidly. Closer INR monitoring and appropriate warfarin dose adjustment are recommended to improve the safety for patients achieving the first INR ≥ 1.8 within 6 days after beginning oral warfarin.