bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anisotropic, Biomorphic Cellular Si3N4 Ceramics with Directional Well-aligned Nanowhisker Arrays Based on Wood-Mimetic Architectures
Authors: Xu Song-Song , Zhou Xiao-Nan , Zhi Qiang , Gao Jun-Jie , Hao Liu-Cheng , Shi Zhong-Qi , Wang Bo , Yang Jian-Feng , Ishizaki Kozo 
Published: September 2021

Abstract
Inspired by the transport behavior of water and ions through the aligned channels in trees, we demonstrate a facile, scalable approach for constructing biomorphic cellular Si3N4 ceramic frameworks with well-aligned nanowhisker arrays on the surface of directionally aligned microchannel alignments. Through a facile Y(NO3)3 solution infiltration into wood-derived carbon preforms and subsequent heat treatment, we can faultlessly duplicate the anisotropic wood architectures into free-standing bulk porous Si3N4 ceramics. Firstly, α-Si3N4 microchannels were synthesized via carbothermal reduction nitridation. And then, homogeneous distributed Y-Si-O-N liquid phase on the walls of microchannel facilitated the anisotropic β-Si3N4 growth to form nanowhisker arrays. The dense aligned microchannels with low-tortuosity enable excellent load carrying capacity and thermal conduction through the entire materials. As a result, the porous Si3N4 ceramics exhibited an excellent thermal conductivity (TC, kR≈6.26 W·m− 1·K− 1), a superior flexural strength (σL ≈ 29.4 MPa), and a relative high anisotropic ratio of TC (kR/kL = ~ 4.1). The orientation dependence of the microstructure-property relations may offer a promising perspective for the fabrication of multifunctional ceramics.
Metastatic Malignant Gastric Glomus Tumour: Multidisciplinary Diagnosis &amp; Treatment of a Rare Clinical Entity
Authors: Francheville Jordan W. , Arnason Thomas , Carter Michael D. , Khodadad Kian , Giacomantonio Carman , Williams Geoff 
Published: September 2021

Abstract
Glomus tumours are uncommon neoplasms that are usually benign, solitary and most often found in the skin and soft tissue of distal extremities. Primary gastric glomus tumors are rare, but well described. Fewer than 15 cases of gastric glomus tumour have been reported to have malignant behaviour with distant metastases. Although surgical resection is effective if feasible, recurrence can occur and there is a paucity of evidence on medical treatment options. Here we present the case of a 69-year-old male with a gastric glomus tumour with metastases to abdominal viscera requiring multidisciplinary care for diagnosis, surgical resection, and multiple lines of systemic/radiation therapy guided by available evidence. Genomic analysis revealed a NOTCH2 rearrangement, described in only two prior works and highlighting future possibilities for targeted therapy.
Impact of end-of-life respiratory modalities on quality of dying and death and symptom relief in patients with interstitial lung disease: a multicenter descriptive cross-sectional study
Authors: Koyauchi Takafumi , Suzuki Yuzo , Sato Kazuki , Hozumi Hironao , Karayama Masato , Furuhashi Kazuki , Fujisawa Tomoyuki , Enomoto Noriyuki , Nakamura Yutaro , Inui Naoki , Yokomura Koshi , Imokawa Shiro , Nakamura Hidenori , Morita Tatsuya , Suda Takafumi 
Published: September 2021

Abstract
Background: Respiratory modalities that applied at end of life may affect burden of distressing symptoms and quality of dying and death (QODD) among patients with end-stage interstitial lung disease (ILD); however, there have been few studies into respiratory modalities applied to these patients near death. We hypothesized that high-flow nasal cannula (HFNC) may contribute to improved QODD and symptom relief in patients with end-stage ILD.Objectives: This multicenter study examined the proportion of end-of-life respiratory modalities in a real-world setting and explored its impact on QODD and symptom relief among patients dying with ILD.Methods: Consecutive patients with ILD who died in four participating institutions in Japan from 2015 to 2019 were identified and divided into four groups according to end-of-life respiratory modality: conventional oxygen therapy (COT), HFNC, non-invasive ventilation (NIV), and invasive mechanical ventilation (IMV). In addition, a mail survey was performed to quantify the QODD and symptom relief at their end of life from a bereaved family’s perspective. QODD and symptom relief were quantified using the Good Death Inventory (GDI) for patients with a completed bereavement survey. The impact of end-of-life respiratory modalities on QODD and symptom relief was measured by multivariable linear regression using COT as a reference.Results: Among 177 patients analyzed for end-of-life respiratory modalities, 80 had a completed bereavement survey. The most common end-of-life respiratory modality was HFNC (n=76, 42.9%), followed by COT (n=62, 35.0%), NIV (n=27, 15.3%), and IMV (n=12, 6.8%). Regarding the place of death, 98.7% of patients treated with HFNC died outside the intensive care unit. Multivariable regression analyses revealed patients treated with HFNC had a higher GDI score for QODD [partial regression coefficient (B)=0.46, 95% CI: 0.07–0.86] and domain score related to symptom relief (B=1.37, 95% CI: 0.54–2.20) than those treated with COT. Conclusion: HFNC was commonly used in patients with end-stage ILD in real-world setting and was associated with higher QODD and better symptom relief. HNFC may contribute to improved QODD and symptom relief in these patients.
Phenotypic and expression QTL integration allows the refinement of loci associated with pig carcass and meat quality traits
Authors: Hérault Frédéric , Vincent Annie , Randriamanantena Ando Yoanne , Damon Marie , Cherel Pierre , Roy Pascale Le 
Published: September 2021

Abstract
Background: Many quantitative trait loci (QTLs) affecting pig meat and carcass quality traits have been reported. However, in most cases, the length of these phenotypic QTLs (pQTLs) is large. Hence, the identification of candidate genes and causative polymorphisms hidden behind those pQTLs remains a difficult task. Combining gene expression, phenotype and genotype data in an integrative genomics approach may help to identify regulatory networks and pathways underlying such complex traits. In the present study, we used genome-wide association study (GWAS) and linkage disequilibrium linkage analysis (LDLA) approaches to identify longissimus muscle (LM) and semimembranosus muscle (SM) expression QTLs (eQTLs). The locations of these eQTLs were compared to those of pQTLs previously mapped in the same population of commercial-type pigs. Colocalized eQTLs/pQTLs could help to identify candidate genes and pathways involved in pig carcass and meat quality trait determination. Results: Both approaches led us to identify 1,253 and 1,109 genome-wide significant eQTLs for LM and SM, respectively. We identified only one common eQTL between the two muscles and a few significant common eQTLs between methodologies : 16 in SM and 1 in LM. A total of 192 overlapping locations were identified between eQTLs and pQTLs. Colocalization highlighted some genes involved in muscle development, adipogenic processes or ion calcium homeostasis. These eQTLs allowed us to refine previously identified pQTLs related to carcass and meat quality traits. However, in most cases, the refined loci were still large and contained several coding and noncoding genes. Conclusions: Our results shed light on the muscle-specific genetic control governing mRNA expression and hence controlling the development of pig carcass and meat quality traits. Moreover, colocations between eQTLs and pQTLs implicated genes potentially involved in muscle development, adipogenic processes or ion calcium homeostasis in the pathways governing these traits. Finally, our results allowed us to refine QTLs controlling meat quality traits and to highlight the possible involvement of long noncoding RNAs in the architecture of regulatory networks governing complex traits such as pig carcass and meat quality traits.
Assessing the potential repercussions of the COVID-19 pandemic on global SDG attainment
Authors: Doi Hideyuki , Osawa Takeshi , Tsutsumida Narumasa 
Published: September 2021

Abstract
The coronavirus disease (COVID-19) pandemic has led to a worldwide lockdown, and this restriction on human movements and activities has significantly affected society and the environment. This study examined the consequences of global lockdown for human movement and nitrogen dioxide (NO2) emissions using an air pollution index and dataset and satellite image analyses. We also evaluated the immediate (during lockdown) and persistent (after lockdown) effects of lockdown on achieving the Sustainable Development Goals (SDGs). Our analysis revealed a drastic reduction in human movement and NO2 emissions and showed that many SDGs were influenced both immediately and persistently due to the global lockdown. We observed immediate negative impacts on four goals and positive impacts on five goals, especially those concerning economic issues and ecosystem conservation, respectively. The persistent effects of lockdown were likely to be predominantly reversed from their immediate impacts due to economic recovery. The global lockdown has influenced the global community’s ability to meet the SDGs, and our analysis provides powerful insights into the status of the internationally agreed-upon SDGs both during and after the COVID-19-induced global lockdown.
Determinants of Government Expenditure In Southwest Nigeria
Authors: Ilugbusi Bamidele Segun , Ogundipe Adebayo Tunbosun , Ojo Oluwasegun David 
Published: September 2021

Abstract
This study examined the determinants of government expenditure in Southwest Nigeria. The study adopted ex-post facto research design and it covered 10 years, spanning from 2010 to 2019. The panel data used was sourced from the CBN statistical bulletin (2019) and the annual budget of each of the sampled states. Panel data estimation techniques were used and based on the most consistent and efficient estimation, it was discovered that internally generated revenue exerts a positive significant effect on both capital and recurrent expenditure to the tune of1.315 (p=0.000 < 0.05) and 0.670(p=0.001 < 0.05) respectively. It was equally discovered that statutory allocation exerts a positive but insignificant effect on both capital and recurrent expenditure for the period covered to the tune of 0.34 (p=0.236 > 0.05) 0.389 (p=0.065 > 0.05) respectively. Also, it was discovered that domestic debt exerts a negative insignificant effect on capital expenditure to the tune of -0.061 (p=0.733 > 0.05). Finally, domestic debt has a positive but insignificant effect on recurrent expenditure to the tune of 0.109 (p=0.352 > 0.05). It was established that internally generated revenue, statutory allocation and domestic debt are the determinant factors of public expenditure across all the states in the Southwest region of Nigeria. Thus, it was recommended that available revenue should be judiciously utilized on the pressing needs of the state. While revenue is needed for the functionality of the government, state governments are urged to embrace more capital projects through which additional revenue might be generated.
Ovarian steroid cell tumors, not otherwise specified: Analysis of nine cases with a literature review
Authors: Lin Mengyan , Lu Lingjia , Xu Shuhang , Liang Yun , Cheng Xiaodong , Wang Fenfen 
Published: September 2021

Abstract
Objective
Ovarian steroid cell tumors (SCTs), not otherwise specified (NOS), are rare, with few large studies. The purpose of this study was to analyze the clinical features, prognosis, and treatment choices for SCT-NOS patients of different age groups.
Methods
This was a retrospective study. We identified nine SCT-NOS cases, confirmed by post-operative histopathological examination, and analyzed clinical features, surgical procedures, and follow up outcomes. We also reviewed cases reports of SCT-NOS.
Results
A total of nine cases were included. The age range was 9–68 years (mean, 41.89 ± 19.72 years). Clinical features included virilization, amenorrhea, abdominal pain, vaginal bleeding, isosexual precocious puberty, Cushing’s syndrome, and abnormal weight gain with elevated testosterone levels. The follow up interval ranged 5–53 months and no recurrence was observed.
Conclusion
Ovarian SCTs covered all age groups, with manifestations of androgen excess. Younger patients appeared to have a more favorable prognosis, which provided more opportunities for these patients to pursue treatment options that will preserve reproductive function.
Developmental exposure to the A6-pesticide causes changes in tyrosine hydroxylase gene expression, neurochemistry, and locomotor behavior in larval zebrafish
Authors: Ahmed NASRI , Pierre-André Lafon , Mezni Amine , Clair Philippe , Cubedo Nicolas , Mahmoudi Ezzeddine , Beyrem Hamouda , Rossel Mireille , Perrier Véronique 
Published: September 2021

Abstract
In recent years, the increase in the synthesis of biopesticides for alternative agricultural uses has necessitated the study of their impacts. Among these compounds, several of them are known to exert endocrine-disrupting effects causing deregulation of a variety of physiological functions affecting cell signaling pathways involved in neural cell differentiation leading to developmental neurotoxicity. In this current paper, we thus determined the impact of the biopesticide A6 on zebrafish larvae, which is structurally linked to estrogenic endocrine disruptors. The objective of this study was to define the toxicity of A6, the mechanisms responsible, and to evaluate its effects on the locomotor activity at nanomolar concentrations (0, 0.5, 5, and 50 nM). We show through its blue fluorescence properties that A6 accumulates in different parts of the body as intestine, adipose tissue, muscle, yolk sac and head. We display also that A6 disrupt the development and affects the function of the central nervous system, especially the expression of tyrosine hydroxylase (TH) in dopaminergic neurons. We studied whether A6 disturbs the target genes expression and recorded that it downregulated genes embroiled in TH expression, suggesting that A6’s neurotoxic effect may be the result of its binding propinquity to the estrogen receptor.
Employee Monetary Compensation and Employee Job Satisfaction
Authors: Watkins Randolph , Fusch Patricia 
Published: September 2021

Abstract
It is known employee job satisfaction is related to employee motivation, performance, retention, and other factors which are beneficial to the employee and the employer. In recent decades, some have used the work of Self-Determination Theory to claim pay is irrelevant and promote the idea it is an employee’s commitment, attitude, and the programs the employer offers the employee that are important to employee satisfaction, motivation, performance, morale, and retention. However, the work of Self-Determination Theory has neither stated nor confirmed this concept. In a study considering if and to what extent a relationship exists between employee rate of monetary compensation and employee job satisfaction, it was found a statistically significant positive relationship exists between employee rate of monetary compensation and employee overall, extrinsic, and intrinsic job satisfaction. The sample consisted of N = 129 employees of Fortune 500 companies within the United States of America. Utilizing Spearman’s rank-order correlation employee overall job satisfaction resulted in 𝜌 = .290, employee extrinsic job satisfaction resulted in 𝜌 = .227, and employee intrinsic job satisfaction resulted in 𝜌 = .325 all demonstrating a positive relationship with employee rate of monetary compensation. This article discusses the current literature, results, and implications.
Nonlinearity Analysis of Quantum Capacitance and its Effect on Nano-Graphene Field Effect Transistor characteristics
Authors: MUNINDRA MUNINDRA , NAND DEVA 
Published: September 2021

Abstract
A simple, compact, and fundamental physics-based quasi-analytic model for Single layer graphene field effect transistors (GFETs) with large area graphene is presented in which the quantum mechanical density gradient method is utilised. The basic device physics of the two-dimensional (2D) graphene channel is studied analytically. This modeling leads to the precise drain current calculation of the GFETs. The drain current calculation for GFETs starts from charge carrier concentration, its density of states and quantum capacitance(QC). QC depends on the channel voltage as a function of gate to source voltage Vgs and drain to source voltage Vds primarily. The formulation of the drain current with velocity saturation has been done by the Monte Carlo simulation method. The performance of the analytical GFETs model is present the precise values of QC, its impact on drain current and transfer as well as output characteristics. The impact of QC at nanometer technology adds the nonlinearity to characteristics curves. The proposed method provides better results as compared with the previous analytical and simulated results.
On the tensile creep deformation behaviour of wrought single-phase γ-TiAl
Authors: Saha Mainak 
Published: September 2021

Abstract
Creep deformation behaviour in single phase γ-TiAl alloy has been an extensively studied topic since the late 1970s. A lot of literatures have reported creep behaviour of γ-TiAl alloys, manufactured using different processing techniques [1]–[7]. The present discussion revisits the original work on understanding the tensile creep deformation behaviour of wrought single-phase γ-TiAl alloy by Hayes et al. [8] and is aimed to develop an understanding of steady state creep, through strain vs strain rate and strain vs ln(strain rate) plots. Besides, it also attempts to study the variation of stress exponent with temperature between 760–900⁰C and also, to determine activation energies using the two most common approaches, namely: Zener-Hollomon (Z-H) [9] and Sherby-Dorn (S-D, temperature compensated time approach) [10] for stress levels of 69.4 and 103.4 MPa between 760–900⁰C.
Research progress of sustainable brownfield redevelopment planning and design: Based on visual bibliometric analysis
Authors: MASRABAYE Francis , Zheng Bohong , Guiradoumngue Gerald Madjissembaye , Zheng Jian 
Published: September 2021

Abstract
Environmental and urban sciences have shown that brownfield problems have a significant impact on human behavior and its environment. Understanding the sustainable planning and redevelopment of brownfields can therefore help governments and financial partners to consider sustainable urban policies as a key priority. This study presents a bibliometric analysis of research publications on the sustainable redevelopment of brownfields through the Scopus database since 1990. The redevelopment of brownfields having an essential role in urban sustainability, so research trends on sustainable redevelopment brownfields in previous literature are revealed. To our knowledge, the bibliometric analysis of the term sustainable redevelopment of brownfields is not yet an accentuated field of research. To do this, this study aims to fill this gap by offering a broad overview of the bibliometric analysis of the literature relating to this term. Brownfield and contaminated land are used as a keyword in the article titles taken from the Scopus database on September 07, 2021. A total of 7197 scientific articles (Scopus) were reviewed to show how the research on " brownfields or contaminated land” has emerged and developed. Social media analysis (VOSviewer) was used for data visualization and Harzing's Publish or Perish is used for metrics and citation analysis. The results showed an increase in the growth rate of the literature on sustainable brownfield redevelopment since 1990, particularly from 2011 to 2020. Research related to the sustainable redevelopment of brownfields has involved various authors and is published in various languages. There are 160 authors from 126 countries and 160 institutions. The China is the largest contributor to this study, followed by the United States and United Kingdom. The Chemosphere Journal has published the most articles on the sustainable redevelopment of brownfields. Although our results also indicate that studies on the sustainable redevelopment of brownfields are mainly carried out in the field of environmental sciences. Some avenues for future research have been analyzed in three directions so that sustainable development can easily be integrated into a brownfield redevelopment project.
Nintedanib reduces corticosteroid resistance pulmonary fibrosis induced by bleomycin in mice by increasing the expression of β3 &amp; β6 integrins
Authors: alghamdi doha omar , kawy Hala S Abdel , Damanhouri Zhair A 
Published: September 2021

Abstract
Background: Corticosteroid resistance pulmonary fibrosis is a major health problem. This study aimed to determine the effectiveness of nintedanib on corticosteroid resistance pulmonary fibrosis induced by bleomycin in mice. Methods: The mice were divided into five groups 12 mice each. control group, BLM group received single dose of bleomycin (BLM), BLM+MP group received BLM and methylprednisolone (MP), BLM+NIN group received BLM and nintedanib(NIN) and BLM + NIN + MP group. The lung tissues were obtained for biochemical analysis, gene expression and histopathological examination on day 7 and day 28. Results: after 7 days, both NIN groups showed a significant decrease in the levels of interleukin-2, interleukin-4, interferon-gamma, lung tumor necrosis factor-alpha, Malondialdehyde and lung water content with a significant increase in the Glutathione level in lung tissues compared to MP group. After 28 days, both NIN groups showed a significant reduction in hydroxyproline, and Trans-forming Growth Factor beta lung tissues contents compared to MP group, and they showed a positive effect on the expression of β 3 &β6 integrins compared to the negative effect of MP group. Histopathologically, both NIN groups showed significant improvement compared to MP group by H&E and Masson’s trichrome stains. Immunohistochemical staining revealed negative BCL-2 expression in the cytoplasm of bronchiolar epithelium in both NIN groups after 7 and 28 days of treatment. Lung tissue morphometric studies showed significant improvement of pathological changes induced by BLM in both NIN groups. Conclusion: Altogether, our data indicates that nintedanib overcame corticosteroid resistance pulmonary fibrosis induced by bleomycin.
Assessment of climate change impact on water availability in the upper Dong Nai River Basin, Vietnam
Authors: Khoi D. N. , Nguyen V. T. , Sam T. T. , Mai N. T. H. , Vuong N. D. , Cuong H. V. 
Published: September 2021

Abstract
On a global scale, climate change is projected to have detrimental impacts on water availability. This situation will become more severe owing to accumulated impacts of climate change and anthropogenic activities. This study aims to investigate climate change impact on water availability in the upper Dong Nai River Basin using the Soil and Water Assessment Tool (SWAT) and Water Evaluation and Planning (WEAP) models. Future rainfall scenarios were downscaled from five different general circulation models under RCP4.5 and RCP8.5 using the Long Ashton Research Station Weather Generator (LARS-WG) tool. Under the climate change impact, annual river discharge in the study region is generally projected to have upward trends in the future, except for the near-future period of the 2030s under RCP4.5. In addition, dry-seasonal river discharge is expected to be increased in the future. Considering the baseline condition of water use, there was an annual water shortage of approximately 32.9 × 103 m3, which mostly occurred in the dry season from January to March. Climate change may reduce the water shortage in the study region ranging from 7.0 to 30.1% in the future. Under the combined impacts of climate change and increasing water demand, the water shortage will vary from −18.6 to 6.0% in the future. The results can provide valuable insights to implement appropriate future water resources planning and management in the study region.