bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Sustainable Route From Quartz to Bifunctional Material with Adsorbed Lanthanides for Enhanced Fluorescent Activation in Doxycycline Sensing
Authors: Semeshko Olha , Fizer Maksym , Sliesarenko Valeriia , Briancin Jaroslav , Bondarchuk Oleksandr , Lobnik Aleksandra , Melnyk Inna 
Published: December 2024

AbstractA nanosized bifunctional adsorbent with diamino and phenyl groups on its surface is synthesized through the functionalization of silica derived from quartz. The composition, morphology, and particle size of the functionalized silica are characterized using various physicochemical methods. The material demonstrates high sorption properties for La(III) and Ce(III), both found in Ni‐MH batteries, as well as Eu(III). The synthesized functionalized silica, with adsorbed lanthanides, is employed for sensor‐based detection of doxycycline in aqueous solutions. After sorbing lanthanides, the bifunctional adsorbent shows a linear response to doxycycline in the concentration range of 0.005–10.0 µm, with a detection limit of 0.15 µm L−1 and a quantification limit of 0.44 µm L−1. The increase in photoluminescence signal upon the addition of doxycycline is explained using Judd–Ofelt theory. Experimental W2 and W4 parameters of the Eu‐doped nanomatrix are determined to be 1.44 × 10−20 cm2 and 8.55 × 10−20 cm2, respectively, with these values increasing to 73.40 × 10−20 cm2 and 35.58 × 10−20 cm2 upon the addition of doxycycline. A significant increase in the radiative emission rate from 196 s−1 to 1977 s−1 is observed with doxycycline addition. It is demonstrated that the system containing the three lanthanides exhibits unique sensor properties, attributed to the co‐luminescence of the Eu(III) ion.
Fabrication of Perovskite Solar Cells: A Focused Review on Manual Deposition Methods
Authors: Zarabinia Nazila , Brown Thomas M. 
Published: December 2024

AbstractThis study provides an overview of manual deposition methods in the fabrication of perovskite solar cells, including drop casting, blade coating, spray coating, soft applicator, and other innovative methods. These methods can easily be tested in all laboratories at a small cost without buying expensive deposition equipment and can be a point of entry for researching this exciting field. Furthermore, new ideas and methods are first mostly developed and tested manually, and then automation happens at a second stage where precision engineering takes over. The latter typically enables higher performance and large‐scale manufacturing. This underlies the importance of implementing and understanding manual fabrication and providing a comparison of manual vs automation modes, which is the objective of this review. The analysis will be of interest to all those researchers wanting to understand or implement conventional or innovative manual methods for fabricating perovskite solar cells and their benefits as well as performance limitations compared to their automated counterparts.
Revealing Self‐Driven Broadband Photodetection Using Heterojunction of Bi2Se3 and Low‐Temperature Laser Molecular Beam Epitaxy Grown GaN on SrTiO3 (100) Substrate
Authors: Aggarwal Vishnu , Kumar Rahul , Gautam Sudhanshu , Yadav Aditya , Pradhan Bipul Kumar , Ganesan Ramakrishnan , Gupta Govind , Kumar M. Senthil , Walia Sumeet , Kushvaha Sunil Singh 
Published: December 2024

AbstractOptoelectronic properties of GaN are underexplored on good lattice matching SrTiO3 (STO) due to STO's instability at the high GaN growth temperatures (800–1100 °C) required by traditional techniques. Here, GaN is grown on STO (100) at lower temperatures (500, 600, and 700 °C) using the laser‐assisted molecular beam epitaxy (LMBE) technique, and their morphological, crystalline, optical, and photodetection properties are analyzed. Further, heterojunction of Bi2Se3 thin film (bandgap of 0.3 eV) is formed on the highest photo‐responsive LMBE‐GaN/STO to fabricate a self‐powered broadband photodetector. The fabricated self‐powered heterojunction photodetectors device exhibits a high responsivity of 2.93 × 102 mAW−1 in ultraviolet region and a notable responsivity of 2.3 and 12 mAW−1 in visible and near‐infrared spectral regions, respectively. In addition, photoresponse properties of fabricated devices on bare LMBE‐GaN and its heterojunction are compared under UV light illumination. The photoresponsivity of heterojunction in UV region is estimated to be 3.05 × 104 mAW−1, which is enhanced by 100% compared to bare LMBE‐GaN. Combining the unique optoelectronic properties of GaN and rigidity of STO, epitaxy of GaN on STO enables construction of robust photodetector devices. Further, Bi2Se3‐functionalized GaN can provide self‐sufficient and high‐quality futuristic optoelectronics devices.
Regiodivergent Reactions of 2‐Alkynyl Aziridines with Grignard Reagents
Authors: Ji Wen‐Tao , Ping A‐Nan , Yang Gaosheng , Chai Zhuo 
Published: December 2024

AbstractHerein, we report regiodivergent nucleophilic attack of Grignard reagents to 2‐alkynyl aziridines. Under the catalysis of a Cu(I)‐diphosphine complex, benzylic Grignard reagents add to the carbon‐carbon triple bond of the aziridines to deliver α‐allenylamines in moderate to excellent yields; the direct addition of the Grignard reagents to the aziridines in the absence of catalyst provided homopropargylic amine derivatives. Both reactions could proceed in highly enantiospecific ways. Further synthetic manipulations of these products enable rapid access to diverse useful heterocyclic molecular scaffolds.
Impact of Transition Metals and Electrocatalyst Layer Thickness on the Pt‐Based Cathodes of Proton Exchange Membrane Fuel Cells – Do Multimetallic Electrocatalysts Necessarily Yield an Improved Performance?
Authors: Sgarbi Ricardo , Ait Idir William , Labarde Quentin , Jourdin Camille , Martin Vincent , Andreetta Daniele , Wu Peizhe , Negro Enrico , Bassetto Fabio , Mainka Julia , Dillet Jérôme , Marty Clémence , Micoud Fabrice , Noto Vito Di , Kulesza Pawel , Lottin Olivier , Chatenet Marian 
Published: December 2024

AbstractThe interplay between i) cathodic electrocatalytic layer (EC layer) features of proton exchange membrane fuel cell (PEMFC), focusing on the oxygen reduction reaction (ORR) electrocatalyst (EC) and the Pt loading; and ii) the PEMFC performance and durability is evaluated. An innovative hierarchical “core–shell” carbon nitride multimetallic ORR electrocatalyst (“PtCuNi/C” H‐EC) is compared with a conventional Pt/C benchmark. The various contributions to PEMFC performance at beginning of test (BOT) are isolated and correlated to the physicochemical features of the ORR EC and the cathodic EC layer. The PEMFC durability is investigated extensively via accelerated stress tests (ASTs) mimicking long‐term operation. Particular attention is dedicated to determine how ageing affects: i) PEMFC cell voltage; and ii) the cathode electrochemically active surface area (ECSA). “Post‐mortem” studies are carried out to probe how ageing influences the cathodic EC layer features, including: i) chemical composition; ii) elements distribution; iii) EC morphology; and iv) structure and crystal size of the Pt‐based metal nanoparticles bearing the active sites. Integrating the experimental results allows to identify both the positive and the detrimental effects triggered by the introduction of transition metals (TMs) in the ORR EC on the factors modulating PEMFC performance and long‐term operation.
Understanding Cathode–Electrolyte Interphase Formation in Solid State Li‐Ion Batteries via 4D‐STEM
Authors: Paranamana Nikhila C. , Werbrouck Andreas , Datta Amit K. , He Xiaoqing , Young Matthias J. 
Published: December 2024

AbstractInterphase layers that form at contact points between the solid electrolyte (SE) and cathode active material in solid‐state lithium‐ion batteries (SS‐LIBs) increase cell impedance, but the mechanisms for this interphase formation are poorly understood. Here, we demonstrate a simple workflow to study cathode–electrolyte interphase (CEI) formation using 4D‐scanning transmission electron microscopy (4D‐STEM) that does not require SS‐LIB assembly. We show benefits of MoCl5:EtOH as a chemical delithiating agent, and prepare chemically delithiated cathode LiNi0.6Co0.2Mn0.2O2 (NMC) powder in contact with Li10GeP2S12 (LGPS) SE powder as a SS‐LIB CEI surrogate. We map the composition and structure of the CEI layers using 4D‐STEM, energy dispersive X‐ray spectroscopy (EDS), and electron pair distribution function analysis (ePDF). EDS indicates O migration from NMC into LGPS. ePDF analysis indicates sulfate and phosphate formation localized on the surface of LGPS, as well as Li2O formation within the LGPS phase, and self‐decomposition of NMC. These results are consistent with an electrochemical self‐discharge mechanism for interphase formation arising from coupled redox reactions of sulfur oxidation in LGPS and transition metal reduction in NMC. This suggests that coatings which stop anion transport but allow Li+ and e− transport may prevent interphase formation and reduce impedance in SS‐LIBs.
High Energy Density Non‐Contact Bidirectional Spinning Oscillating Float‐Type Triboelectric Nanogenerators for Energy Extraction From Irregular Waves
Authors: Chen Feng , Dai Xianggang , Wu Xiaobo , Ding Zhenxing , Gao Yidong , Pang Yaokun , Jiang Tao , Luo Jianjun , Hong Zhanyong , Wang Zhong Lin 
Published: December 2024

AbstractThe pursuit of sustainable and self‐sufficient energy solutions has become critical for the advancement of marine Internet of Things (IoT) technologies. While triboelectric nanogenerators (TENGs) have shown great potential in harnessing high‐entropy, low‐frequency wave energy, their practical applications are hindered by low power output and issues related to frictional wear. Hence, this research presents a novel non‐contact bidirectional spinning oscillating float‐type triboelectric nanogenerator (OF‐TENG) for efficient wave energy harvesting. Utilizing a planetary gear and bidirectional rotation structural design, low‐frequency vertical wave energy with random and multi‐directional conditions can be converted into high‐frequency rotational energy. At a frequency of 0.5 Hz, the OF‐TENG achieves a peak output power of 93.48 mW, and an average output volumetric power density of 31.3 W m⁻3. Furthermore, the non‐contact working mode ensures robust output stability, with no significant performance degradation observed after 5,680,000 working cycles. An intelligent self‐powered marine ranching system for automatic feeding and water quality monitoring is further developed based on the OF‐TENG. This work not only provides an effective solution for harvesting low‐frequency wave energy, but also promotes the development of smart marine IoT technologies and marine agriculture.
Synergistic Configurational Entropy and Iron Vacancy Engineering in Na4Fe3(PO4)2P2O7 Cathode for High‐Power‐Density and Ultralong‐Life Na‐Ion Full Batteries
Authors: Hu Xiaoping , Liang Shuquan , Lin Jiande , Ren Wen , Fu Shengqiao , Cao Zhitao , Zhang Ting , Zhang Lei , Cao Xinxin 
Published: December 2024

AbstractNa4Fe3(PO4)2P2O7 cathode exhibits extensive potential for high‐power applications, owing to its large sodium ion diffusion channels, low cost, and suitable operating voltage. However, it suffers significant capacity degradation due to the inevitable NaFePO4 impurity. Herein, a synergistic strategy is proposed that integrates high entropy doping with Fe vacancy engineering, which not only preserves the phase purity but also provides additional active sites and further stabilizes its crystal structure. A novel Na4Fe2.61(Ni, Co, Mn, Cu, Zn, Mg)0.05(PO4)2P2O7 cathode has been successfully synthesized by a simple sol‐gel method, which exhibits an ultralong cycle life (over 15000 cycles at 5 A g−1) and outstanding rate capability (61.1 mAh g⁻¹ at 10A g−1). Additionally, a combined solid‐solution and biphasic reaction mechanism in sodium storage process is thoroughly confirmed. Notably, benefiting from the rational design of N/P ratio and well‐matched capacitive contributions, the full cells assembled with hard carbon anodes exhibit superior cycling durability, sustaining over 1000 cycles at a high current density of 1 A g⁻¹ without severe capacity deterioration. Such highly durable full cells with low N/P ratioand common ester‐based electrolytes have never been reported before. The present work offers new perspectives to expedite the commercialization of low‐cost, high‐power‐density sodium‐ion batteries.
Carbon‐zero co‐production of hydrogen and chemicals boosted by directional hydrogen spillover via terminated interface
Authors: Guo Xuanlin , Wu Huifang , Zhao Yang , Zheng Lirong , Wang Qian , Li Dianqing , Feng Junting 
Published: December 2024

AbstractAcceptorless dehydrogenation of biomass‐alcohol provides an appealing route for co‐producing green H2 and high‐value chemicals. However, the sluggish H species binding step severely inhibits reaction equilibrium and cause C‐C cleavage. Herein, we propose a unique directional H spillover strategy driven by controlling electron transport direction via constructing Au‐O‐Cu‐O‐Mg/Al interfacial structure, to allow H species transfer from O‐H dehydrogenation Cu2+ site to C‐H dehydrogenation Au site to promote H2 formation. The structure that each Cu precisely terminated by Mg/Al is inherited from layered double hydroxides with orderly dispersed atom arrangement. Comprehensive studies substantiate that the unreducible Mg2+/Al3+ blocks electron transfer toward support, whereas Au‐O‐Cu electronic interaction drives H spillover from the support to Au. The Au/CuMgAl catalyst demonstrated unprecedentedly high glycerol dehydrogenation activity, showing 3–10 times turnover frequency (1.18 × 104 h−1) than other biomass‐derived H2 formation system, co‐producing lactic acid with selectivity up to 98.8%.
Longitudinal cognitive performance of participants with sporadic early onset Alzheimer's disease from LEADS
Authors: Hammers Dustin B. , Eloyan Ani , Taurone Alexander , Thangarajah Maryanne , Gao Sujuan , Beckett Laurel , Polsinelli Angelina J. , Kirby Kala , Dage Jeffrey L. , Nudelman Kelly , Aisen Paul , Reman Rema , La Joie Renaud , Lagarde Julien , Atri Alireza , Clark David , Day Gregory S. , Duara Ranjan , Graff‐Radford Neill R. , Grant Ian , Honig Lawrence S. , Johnson Erik C. B. , Jones David T. , Masdeu Joseph C. , Mendez Mario F. , Womack Kyle , Musiek Erik , Onyike Chiadi U. , Riddle Meghan , Rogalski Emily , Salloway Steven , Sha Sharon J. , Turner Raymond Scott , Wingo Thomas S. , Wolk David A. , Carrillo Maria C. , Rabinovici Gil D. , Dickerson Bradford C. , Apostolova Liana G. ,   the LEADS Consortium
Published: December 2024

AbstractINTRODUCTIONEarly‐onset Alzheimer's disease (EOAD) manifests prior to the age of 65, and affects 4%–8% of patients with Alzheimer's disease (AD). The current analyses sought to examine longitudinal cognitive trajectories of participants with early‐onset dementia.METHODSData from 307 cognitively normal (CN) volunteer participants and those with amyloid‐positive EOAD or amyloid‐negative cognitive impairment (EOnonAD) were compared. Cognitive trajectories across a comprehensive cognitive battery spanning 42 months were examined using mixed‐effects modeling.RESULTSThe EOAD group displayed worse cognition at baseline relative to EOnonAD and CN groups, and more aggressive declines in cognition over time. The largest effects were observed on measures of executive functioning domains, while memory declines were blunted in EOAD.DISCUSSIONEOAD declined 2–4× faster than EOnonAD, and EOAD pathology is not restricted to memory networks. Early identification of deficits is critical to ensure that individuals with sporadic EOAD can be considered for treatment using disease‐modifying medications.Highlights
Represents the most comprehensive longitudinal characterization of sporadic EOAD to date.
The trajectory of cognitive declines was steep for EOAD participants and worse than for other groups.
Executive functioning measures exhibited the greatest declines over time in EOAD.
Plasma Aβ42/Aβ40 is sensitive to early cerebral amyloid accumulation and predicts risk of cognitive decline across the Alzheimer's disease spectrum
Authors: Trelle Alexandra N. , Young Christina B. , Vossler Hillary , Ramos Benitez Javier , Cody Karly A. , Mendiola Justin H. , Swarovski Michelle S. , Guen Yann Le , Feinstein Igor , Butler Robert R. , Channappa Divya , Romero America , Park Jennifer , Shahid‐Besanti Marian , Corso Nicole K. , Chau Kelly , Smith Amanda N. , Skylar‐Scott Irina , Yutsis Maya V. , Fredericks Carolyn A. , Tian Lu , Younes Kyan , Kerchner Geoffrey A. , Deutsch Gayle K. , Davidzon Guido A. , Sha Sharon J. , Henderson Victor W. , Longo Frank M. , Greicius Michael D. , Wyss‐Coray Tony , Andreasson Katrin I. , Poston Kathleen L. , Wagner Anthony D. , Mormino Elizabeth C. , Wilson Edward N. 
Published: December 2024

AbstractINTRODUCTIONThe availability of amyloid beta (Aβ) targeting therapies for Alzheimer's disease (AD) is increasing the demand for scalable biomarkers that are sensitive to early cerebral Aβ accumulation.METHODSWe evaluated fully‐automated Lumipulse plasma Aβ42/Aβ40 immunoassays for detecting cerebral Aβ in 457 clinically unimpaired (CU) and clinically impaired (CI) Stanford Alzheimer's Disease Research Center (Stanford ADRC) participants and 186 CU in the Stanford Aging and Memory Study (SAMS). Longitudinal change in ADRC plasma Aβ42/Aβ40 and cognition and cross‐sectional associations with SAMS memory and tau positron emission tomography (PET) were examined.RESULTSPlasma Aβ42/Aβ40 exhibited high performance in detecting amyloid positivity defined by PET (area under the curve [AUC]: 0.885, 95% confidence interval [CI]: 0.816–0.955). Once abnomal, plasma Aβ42/Aβ40 remained low and predicted cognitive decline in both CU and CI individuals. Among SAMS CU, plasma Aβ42/Aβ40 was associated with poorer hippocampal‐dependent memory and elevated tau accumulation.DISCUSSIONLumipulse plasma Aβ42/Aβ40 is a scalable assay for detection of cerebral Aβ and prediction of risk for cognitive decline across the AD continuum.Highlights
Lumipulse plasma amyloid beta (Aβ)42/Aβ40 exhibited high accuracy in detecting amyloid positivity.
Plasma amyloid‐positive (Aβ+) individuals exhibited stability of Aβ42/Aβ40 over time.
Plasma Aβ42/Aβ40 predicted future cognitive decline across the Alzheimer's disease (AD) spectrum.
Plasma Aβ42/Aβ40 was sensitive to memory and tau burden in clinically unimpaired older adults.
Accelerated ovarian failure results in brain alterations related to Alzheimer's disease that are not recovered by high‐intensity interval training in mice
Authors: Mohammad Ahmad , Finch Michael S. , Rouhana Sarah , Mashouri Parastoo , Barry Ciara , Hubbard Emma F. , Sze Newman , Beaudette Shawn M. , Pyle W. Glen , Power Geoffrey A. , MacPherson Rebecca E. K. 
Published: December 2024

AbstractINTRODUCTIONThe menopausal decline in ovarian estrogen production is thought to increase the risk of Alzheimer's disease; however, this link requires further investigation. The chronological development of this connection is not well defined because of the lack of animal models that recapitulate the time course of menopause. This study characterized the cognitive and neuronal effects of the 4‐vinylcyclohexene diepoxide (VCD) model of ovarian failure in female mice and assessed whether high‐intensity interval training (HIIT) would attenuate impairments.METHODSFemale mice were injected with VCD for 15 days. Novel object recognition tests (NORT) were conducted during (perimenopause) and after (menopause) ovarian failure (n = 7). HIIT was initiated in menopause and mice underwent NORT testing after 2 and 8 weeks of HIIT (n = 5).RESULTSVCD mice had a lower discrimination index, and lower SNAP25 and NeuN expression in perimenopause. HIIT did not recover memory in VCD mice.DISCUSSIONNeuronal changes arise early in the perimenopausal transition and HIIT did not improve recognition memory when initiated in menopause.Highlights
The menopausal decline in ovarian estrogen production increases the risk of Alzheimer's disease (AD).
The chronological development of this connection is not well defined because of the lack of animal models that recapitulate the time course of menopause.
4‐vinylcyclohexene diepoxide (VCD)–induced ovarian failure provides a model that simulates the average human experience in the transition from perimenopause to menopause.
We demonstrate that cognitive and biochemical effects related to AD pathology are present from the earliest available timepoint in perimenopause in VCD mice.
This work highlights the importance of examining the time course in the progression to menopause and the use of VCD as a model to investigate changes in the brain.
Performance of study partner reports in a non‐demented at‐risk sample
Authors: Huang Qi , Bolt Daniel , Jonaitis Erin , Hermann Bruce , Studer Rachel , Du Lianlian , Ryther Brenda , Sparks Lia , Galvin James E. , Johnson Sterling , Langhough Rebecca 
Published: December 2024

AbstractINTRODUCTIONThe Clinical Dementia Rating (CDR) Scale is a gold standard for staging impairment in Alzheimer's disease and other dementias (ADRD). The Quick Dementia Rating System (QDRS) offers similar results in 3 to 5 minutes without a trained clinician. This study aimed to (1) investigate concordance between comparably derived QDRS and CDR global scores, (2) examine item‐level QDRS/CDR agreement, and (3) compare sample characteristics and cognitive performance across QDRS/CDR global concordant/discordant groups.METHODSThe study included 351 QDRS/CDR pairs from 297 participants in the Wisconsin Registry for Alzheimer's Prevention (WRAP). Analyses included descriptive indices of QDRS/CDR agreement, lasso logistic regression, tetrachoric correlations, and linear mixed models.RESULTSThe QDRS global/CDR global concordance rate is 70.66%. Memory item discrepancies were primarily responsible for QDRS/CDR global rating discordance. Average cognitive scores were highest in concordant‐normal QDRS/CDR and lowest in concordant‐abnormal QDRS/CDR.DISCUSSIONThe QDRS effectively screened for impairment in this sample. Future analyses will investigate QDRS relations to ADRD biomarkers.Highlights
The Quick Dementia Rating System (QDRS) effectively screened for impairment in Alzheimer's disease and other dementias (ADRD) in a non‐demented sample.
Concordance rate between QDRSCDR global and Clinical Dementia Rating (CDR) Scale global scores is 70.66%.
Memory item discrepancies primarily cause QDRS/CDR global score discordance.
Cognitive scores are associated with QDRS/CDR concordances/discordances.
Future analyses will explore QDRS relations to ADRD biomarkers.