bluuebunny/crossref_metadata_2025_split huggingface dataset:
Results of osteopathic treatment of infants with psychomotor developmental disorders
Authors: Veber V R , Egorova I A , Zinkevich E R , Chervotok A E 
Published: December 2021

Aim. To compare the effectiveness of osteopathic treatment of infants with psychomotor development disorders with standard treatment in terms of functional status.
Methods. The study was conducted at the Yaroslav-the-Wise Novgorod State University and the Institute of Osteopathic Medicine named after V.L. Andrianov, between 2020 and 2021. The study included 49 children with delayed psychomotor development, of which: the main group consisted of 26 children receiving osteopathic treatment; the control group consisted of 23 children treated with standard therapies. Data gathered included the indicators of the functional health state, complaints of parents, assessed neurological, vegetative, and osteopathic statuses, the psychomotor development in the children according to the ZhurbaMastyukova scale, performed neurosonography. The results were processed using descriptive statistics followed by checking for the significance of the difference by using the Student's t-criterion for related samples.
Results. A comparison of the effectiveness of osteopathic and standard treatment of infants with a delay in psychomotor development by indicators of the functional status was carried out. The need for an integrated approach to therapeutic and diagnostic procedures was substantiated. The number of subjective complaints about the health of children from parents in the main group decreased, while in the control group, it remained the same. Neurological status in children of both groups improved, but the changes are more pronounced in the main group (p 0.05). The outcomes of the treatments indicate for improving psychomotor development of the children in the main group, in the control group, such an increase was only 13.0% (p 0.001).
Conclusion. The results of the study showed that osteopathic treatment of infants with psychomotor development disorders is more effective than standard complex treatment, which is reflected in the improvement of functional health indicators.
Bactibilia-effect on postoperative course and outcome in patients with bilio-pancreatic diseases
Authors: Reddy A. Dinakar , Thota Anuroop , Harsha Vanga Devi 
Published: December 2021

Background: Bactibilia is detrimental to the outcomes of biliary tract surgery. The present study was undertaken to determine the microbial flora of bile and their significance to post-operative infectious complications and morbidity.Methods: A retrospective study of patients with biliopancreatic diseases who underwent surgery from Jan 2017 to March 2020 in a tertiary care hospital were analyzed. The samples were assessed for bile microbiological flora, and a search for their possible link with post-operative infectious complications and morbidity was carried out.Results: A total of 90 bile samples were assessed. The mean age of the study group was 51.8 SD-13.6 years with male predominance. Bactibilia was found in 39 cases (43.3%), mostly in patients with malignant diseases, older than 50 years and females. Escherichia coli was the most common organism. Post-operative infectious complications were seen in twenty cases, thirteen of them in bactibilia-associated patients, showing statistical significance. Statistical significance was found between the presence of pre-operative biliary stent and bactibilia and between diabetes mellitus and bactibilia. Nine out of 24 patients with comorbidities had post-operative infectious complications. No significant relationship was found between pre-operative jaundice and comorbidities with bactibilia. Conclusions: The present study showed a statistically significant relationship between the presence of pre-operative biliary stent and bactibilia and also the incidence of post-operative infectious complications and bactibilia. Microbiological analysis of bile is a valuable tool in prognosticating the post-operative complications, thereby guiding us to provide adequate therapy and helps to establish local antibiotic guidelines.
Cryotherapy with liquid nitrogen for chronic and recalcitrant intertrigo of toe webspaces
Authors: S. Sowmya C. , Sorake Nidhika V. 
Published: December 2021

<p><strong>Background:</strong> The inflammation of the toe web spaces is known as foot intertrigo. Most commonly caused by candida. Important predisposing factors such as diabetes mellitus, obesity and immunosuppression lead to persistence and recurrence. Cryotherapy is a promising, safe, cost-effective, easily available therapeutic approach to treat recalcitrant intertrigo compared to available topical medications. Aim of the study was to observe the clinical improvement and therapeutic response of recalcitrant intertrigo and to observe treatment response based on photographs.</p><p><strong>Methods:</strong> A total of 30 patients who were clinically diagnosed with chronic candida intertrigo (CI) who fulfilled the inclusion and exclusion criteria were enrolled. Cryotherapy was administered with 3 cycles of freeze and thaw of 30 seconds each, every 2 weeks for a maximum of 3 treatment sessions. Follow-up of patients were done for 4 months.</p><p><strong>Results:</strong> Among 30 patients treated, 21 patients showed excellent clinical response, 6 patients showed good response. Only 2 patients showed poor response. Minimal side effects were observed, of which transient pain at the cryotherapy site is the most common. Diabetes was the most common comorbidity with poor response to treatment and recurrence.</p><p><strong>Conclusions:</strong> Cryotherapy can be used as a safe modality of treatment for recalcitrant CI cases unresponsive to topical therapy by providing faster therapeutic response and improving the quality of life in these patients. </p>
Detección de Descargas Parciales en una Instalación Eléctrica Subterránea por Medio de Procesamiento Digital de Imágenes Térmicas
Authors: González-Parada Adrián , Jaramillo-Vacío Rubén , Bosch-Tous Ricard , Casals-Torrens Pau 
Published: December 2021

La instalación de cables de potencia se deben de considerar una serie de factores para asegurar un buen desempeño en su operación y así mejorar notablemente la confiabilidad del sistema donde se encuentra. Durante la instalación se ven involucrados el empleo de accesorios específicos para su conexión a sistemas aéreos o para conexión de equipos, tales accesorios son conocidos como terminales y empalmes. De acuerdo a las estadísticas estos accesorios presentan el 95% de las fallas debido a problemas durante su instalación o vida útil, por lo que es necesario llevar a cabo estudios o monitoreos programados de la operación de las instalaciones eléctricas con el fin de reducir riesgos y prevenir fallas en la instalación. En el presente trabajo se presenta un método de detección incipiente de falla, el cual se basa en el análisis de imágenes termográficas de los accesorios (empalmes y terminales) de media tensión en operación. El objetivo es identificar la zona de una terminal en la que exista una falla incipiente por descargas parciales, las cuales no se pueden observar con una imagen termográfica simple, sino que se requiere realizar un análisis y proceso digital de la imagen termográfica a fin de identificar plenamente el punto de falla en donde con el procesamiento digital de imágenes es posible extraer información que a simple vista no se percibe en una imagen obtenida con una cámara termográfica. Se presentan los resultados obtenidos en laboratorio de fallas previamente establecidas en un modelo de instalación eléctrica subterránea.
Monitoreo en línea de transformadores de potencia. Una revisión crítica de sensores de temperatura, humedad del aceite y gases disueltos
Authors: Salamanca Santiago , Céspedes Alexander , Aponte Guillermo 
Published: December 2021

Los transformadores de potencia son uno de los activos más importantes que conforman las redes eléctricas. Cuando uno de estos activos presenta una falla repentina que involucra la suspensión del suministro de electricidad a los centros de consumo, puede conllevar consecuencias críticas para el sistema de potencia. La mayoría de este tipo de fallas en el transformador, están relacionadas con altos niveles de temperatura, humedad o deterioro de su sistema de aislamiento.
Debido a lo anterior, durante las últimas décadas los sistemas de monitoreo en línea para transformadores de potencia han venido adquiriendo una mayor relevancia e integración a las redes y subestaciones eléctricas. En este trabajo se realiza una revisión crítica de tres de los sensores en línea más importantes para la operación y funcionamiento del transformador, como lo son: temperatura, humedad del aceite y gases disueltos.
Inicialmente, se realiza una introducción referente a la importancia del transformador de potencia y el concepto de monitoreo en línea. Luego, se presenta una breve descripción con los principales hitos históricos de dichos sensores al igual que algunos de sus aspectos técnicos generales. Además, se proponen algunos criterios de comparación y selección citando ejemplos y casos estadísticos de interés. Finalmente, se presentan las conclusiones y recomendaciones del estudio.
Penggunaan Informan Dalam Penyelidikan Tindak Pidana Pencurian Kendaraan Bermotor Roda Dua di Wilayah Polrestabes Surabaya
Authors: Saputra Edi Budi Wibowo 
Published: December 2021

Urgensi kebutuhan akan adanya informan sipil dikarenakan beberapa sebab, yang pertama karena sulitnya menembus masuk lebih dalam ke wilayah jaringan curanmor. Kedua, dikarenakan minimnya informasi mengenai identitas yang diduga pelaku curanmor sehingga dibutuhkan seseorang yang menguasai medan target. Ketiga, perlunya membangun kemitraan antara kepolisian dan masyarakat sebagai basis deteksi dini. Adapun optimalisasi peran informan dalam membantu kepolisian memberantas tindak pidana pencurian kendaraan bermotor roda dua, pertama dilaksanakan melalui kegiatan optimalisasi pola rekrutmen jaringan informan. Kedua, optimalisasi pelatihan bagi jaringan informan sipil yang mutlak harus dilaksanakan guna meningkatkan kompetensi informan. Ketiga, optimalisasi pengawasan dan pengendalian informan yang dimulai dengan kegiatan mulai briefing sampai debriefing. Keempat, optimalisasi koordinasi Satreskrim dan Satintelkam melalui penyusunan Hubungan Tata Cara Kerja Polri (HTCK).
Reopening of Surabaya Zoo in Coronavirus Disease 2019 (Covid-19) Pandemic
Authors: Fitriyanti Puteri Hapsari 
Published: December 2021

High spread of Covid-19 in Surabaya implemented on a Large-Scale Social Restrictions policy. This has impacted on closure of tourist destinations, including Surabaya Zoo. During the closing period, Surabaya Zoo suffered significant losses due to the absence of revenue that impacted on the conservation operations in saving endangered animals. Based on Surabaya Mayor Regulation of New Normal Order Guidelines Number 28 of 2020 as amended by Number 33 of 2020, Surabaya Zoo is reopened. This fact is an interesting issue to study how well the management in handling this situation. The writing method used in this paper is a literature review and primary data collection as a form of best practice that might be adopted in Surabaya Zoo. The results showed that management is succeeded in reopening Surabaya Zoo. The conclusion from this study is Surabaya Zoo is recommended to be reopened during the first stage of New Normal
Estéticas das resistências e o documentário (documento 03)
Authors: Sobrinho Gilberto Alexandre 
Published: December 2021

Na “Trilogia Afro-Campineira” constam três realizações em documentário, em que dirigi, roteirizei e produzi os filmes. São três curtas-metragens focados em protagonistas de processos culturais, religiosos e artísticos, todos defensores de manifestações de matrizes africanas e seus potentes hibridismos, alocados na região metropolitana de Campinas-SP (RMC). Os filmes são Diário de Exus (2015), A Dança da Amizade, Histórias de Urucungos, Puítas e Quijengues (2016) e A Mulher da Casa do Arco-Íris (2017/2018). Desenvolvem-se, nos filmes, o que nomeio como as “estéticas das resistências”, priorizando narrativas afro-diaspóricas, num processo de criação em que confluem estética e política. Esteticamente, o documentário faz convergir os processos de observação, participação (entrevista), performance e “poesia”, num conjunto de imagens e sons centrados em pessoas e espaços que se organizam comunitariamente em torno de códigos afrocentrados. Politicamente, realçam-se o papel da cultura e da religião na afirmação e construção identitária do povo negro, no Brasil, o que adensa a compreensão do papel da cultura na resistência de um povo. Esse texto documenta o processo de realização do terceiro curta-metragem da trilogia, trata-se de A Mulher da Casa do Arco-íris.
Hyaluronic Acid Injections for Knee Osteoarthritis
Authors: Zhu Kevin Y. , Acuña Alexander J. , Samuel Linsen T. , Grits Daniel , Kamath Atul F. 
Published: December 2021

Background:The utilization of hyaluronic acid (HA) for the management of knee osteoarthritis (OA) remains controversial, and more information is needed regarding how its utilization and financial burden have changed over recent years. The purpose of our analysis was to evaluate changes in overall utilization and health-care costs associated with HA injections among Medicare beneficiaries over a contemporary time frame.Methods:The 2012 to 2018 Medicare Fee-for-Service Provider Utilization and Payment Public Use Files (PUFs) were utilized for our analysis. Organized by Healthcare Common Procedure Coding System (HCPCS) codes, these files capture 100% of Medicare Part B claims. Payment and utilization data were collected for all HCPCS codes corresponding to injection of an HA formulation. The number of services involving HA as well as the total cost of HA administration in 2020 U.S. dollars were tabulated. Mann-Kendall trend tests were used to evaluate trends in utilization for providers nationally and when segregated by specialty.Results:Total HA utilization increased significantly from 2012 (n = 1,090,503) through 2018 (n = 1,209,489; p = 0.04). Although orthopaedic surgeons did not demonstrate significant changes in total utilization rates (p = 0.23), the average number of services per orthopaedic surgeon increased significantly (p = 0.02). Reflecting a substantial growth in the number of advanced practice providers (APPs) providing injections, there was a significant increase in utilization and associated costs among physician assistants (p < 0.01) and nurse practitioners (p < 0.01). Total costs associated with HA services increased significantly from $290.10 million to $325.02 million (p < 0.01).Conclusions:Despite the 2013 American Academy of Orthopaedic Surgeons clinical practice guideline recommending against the clinical utility of these injections, HA services continued to be widely implemented among Medicare beneficiaries. Although there were variations across specialties when evaluating overall utilization rates as well as rates per provider, APPs largely contributed to the increase seen in the U.S. over this study period. More data are needed to support continued implementation and spending on this low-value care.
Distinct evolution of infection-enhancing and neutralizing epitopes in the spike protein of SARS-CoV-2 variants (from alpha to omicron) : a structural and molecular epidemiology study
Authors: GUERIN Patrick , YAHI Nouara , AZZAZ Fodil , CHAHINIAN Henri , SABATIER Jean-Marc , FANTINI Jacques 
Published: December 2021

Abstract
Infection-enhancing antibodies may limit the efficiency of Covid-19 vaccines. We analyzed the evolution ofneutralizing and facilitating epitopes in 1,860,489 SARS-CoV-2 genomes stored in the Los Alamos databasefrom June to November 2021. The structural dynamics of these epitopes was determined by molecular modelingof the spike protein on a representative panel of SARS-CoV-2 variants. D614, which belongs to an antibody-dependent-enhancement (ADE) epitope common to SARS-CoV-1 and SARS-CoV-2, has mutated to D614G in2020, which could explain why ADE has not been detected following mass vaccination. A second epitopelocated in the N-terminal domain (NTD), specific of SARS-CoV-2, is highly conserved among most variants. Incontrast, the neutralizing epitope of the NTD showed extensive variations in SARS-CoV-2 variants. The balancebetween facilitating and neutralizing antibodies is in favor of neutralization for the Wuhan strain, alpha and betavariants, but not for gamma, delta, lambda, and mu. The recently emerging omicron variant is atypic as itsmutational profiles affects both neutralization and ADE epitopes. Overall, our data reveal that the evolution ofSARS-CoV-2 has dramatically affected the ADE/neutralization balance. Future vaccines should consider thesefindings to design new formulations adapted to SARS-CoV-2 variants and lacking ADE epitopes in the spikeprotein.
Aquaculture Water Quality Improvement by Mixed Bacillus and Its Effects on Microbial Community Structure
Authors: Li Xue , Wang Tianie , Fu Baorong , Mu Xiyan 
Published: December 2021

Abstract
Nutrients nitrogen and phosphorus pollution in aquaculture is one of the greatest challenges threatening the survival of aquatic organisms, which requires efficient and sustainable remediation approach. Microbial remediation, especially the application of probiotics, has recently gained popularity in improving the water quality and maintaining the health condition of aquatic animals. In the present study, two groups of mixed Bacillus (Bacillus megaterium and Bacillus subtilis (A0+BS) and Bacillus megaterium and Bacillus coagulans (A0+BC)) were applied to aquaculture system of Crucian carp to improve the treatment of nitrogenous and phosphorus compounds. The effects of mixed Bacillus on water quality, and the structure and function of microbial communities in aquaculture water were investigated. Our results showed that the improvement effect of mixed Bacillus A0+BS on water quality was better than that of A0+BC, and the NH4+-N, NO2--N, NO3--N and total phosphorus (TP) concentrations were reduced by 46.3%, 76.3%, 35.6%, and 80.3%, respectively. In addition, both groups of mixed Bacillus increased the diversity of bacterial community and decreased the diversity of fungal community. Microbial community analysis showed that mixed Bacillus A0+BS increased the relative abundance of bacteria related with nitrogen and phosphorus removal, e.g., Proteobacteria, Actinobacteria, Comamonas, and Stenotrophomonas, but decreased the relative abundance of pathogenic bacteria (Acinetobacter and Pseudomonas) and fungi (Epicoccum and Fusarium). The redundancy analysis showed that NH4+-N, NO2--N, and TP were primary environmental factors affecting the microbial community in aquaculture water. PICRUST analysis indicated that all functional pathways in the treatment groups were up-regulated, and all pathways in A0+BS group were richer than those in other groups. These results indicated that mixed Bacillus A0+BS addition produced good results in reducing nitrogenous and phosphorus compounds and shaped a favorable microbial community structure to further improve water quality.
Adverse Pregnancy Outcomes and Maternal Chronic Diseases in the Future: a Cross-sectional Study Using KoGES-HEXA Data
Authors: Cho Geum Joon , Kim Jiae , Kim Ji Young , Han Sung Won , Lee Soo Bin , Oh Min-Jeong , Kim Sa Jin , Shin Jae Eun 
Published: December 2021

Abstract
Purpose Adverse pregnancy outcomes (APOs) are associated with an increased risk of chronic diseases, including cardiovascular disease (CVD) and metabolic syndrome (MS), in the future. We designed a large-scale cohort study to evaluate the influence of APOs (preeclampsia, gestational diabetes mellitus [GDM], stillbirth, macrosomia, and low birth weight) on the incidence of chronic diseases, body measurements, and serum biochemistry in the future and investigate whether combinations of APOs had additive effects on chronic diseases.Methods We used health examinee data from the Korean Genome and Epidemiology Study (KoGES-HEXA) and extracted data of parous women (n = 30,174; mean age, 53.02 years) for the analysis. A logistic regression model was used to estimate adjusted odds ratios (aORs) and 95% confidence intervals.Results The prevalence rate of APOs was 17.4% (5,264 women). Univariate analysis revealed that women with APOs were more frequently diagnosed with chronic diseases and had a family history of chronic diseases compared with women without APOs. In logistic regression analysis, composite APOs were associated with an increased risk of hypertension, diabetes mellitus, hyperlipidemia, angina pectoris, stroke, and MS (aOR: 1.093, 1.379, 1.269, 1.351, 1.414, and 1.104, respectively), after adjustment for family history and social behaviors. Preeclampsia and GDM were associated with an increased risk of some chronic diseases; however, the combination of preeclampsia and GDM did not have an additive effect on the risk.Conclusion APOs moderately influenced the future development of maternal CVD and metabolic derangements, independent of family history and social behaviors.
Surgical Outcomes and Fusion Rate Following Spine Fusion Surgeries in Patients with Chronic Kidney Disease: According to Kidney Function
Authors: Jo Dae Jean , Choi Ho Yong 
Published: December 2021

Abstract
PURPOSE. To evaluate the surgical outcomes and fusion rate following lumbar fusion surgeries in patients with chronic kidney disease (CKD) according to kidney function.METHODS. From March 2017 to February 2021, 54 consecutive adult patients with CKD who underwent spine fusion surgery were enrolled. According to the glomerular filtration rate (GFR) categories, 35 patients were classified into the non-end-stage renal disease (ESRD) group (GFR categories 3a–4, eGFR 15–59 mL/min/1.73 m2) and 19 patients into the ESRD group (GFR category 5, eGFR <15 mL/min/1.73 m2).RESULTS. Baseline characteristics did not differ between the groups. The mean number of fused vertebrae (4.9 ± 2.3 vs. 4.1 ± 2.0, p = 0.122), operative time (228.4 ± 129.6 min vs. 160.5 ± 87.5 min, p = 0.113), and surgical bleeding (743.1 ± 630.5 mL vs. 539.5 ± 384.4 mL, p = 0.354) did not differ between the groups. The rates of medical complications (25.7% vs. 52.6%, p = 0.048) and 3-month readmission (8.6% vs. 35.3%, p = 0.045) were significantly different between the groups. The 3-month mortality tended to be higher in the ESRD group (10.5%) than which in the non-ESRD group (2.9%), but the difference was not statistically significant (p = 0.280). The rate of pseudarthrosis was significantly higher in the ESRD group (35.3%) than in the non-ESRD group (9.1%, p = 0.047).CONCLUSIONS. Surgeons should be aware of the high morbidity and the pseudarthrosis when considering spine surgeries in patients with ESRD.