bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Functional Dyspepsia with Depression and Anxiety: A Systematic Review
Authors: Esterita Tasia , Dewi Sheilla , Suryatenggara Felicia Grizelda , Glenardi Glenardi 
Published: May 2021

Background and Aims: Functional dyspepsia (FD) symptoms may lead to depression or anxiety in affected individuals and vice versa. These individuals often have more serious somatic symptoms, longer disease recovery time, and tend to consume more medical resources and health care costs. Therefore, recognition of depression and anxiety is crucial to improve clinical outcome in FD patients. The aim of this study is to systematically review the association of functional dyspepsia with depression and anxiety.
Methods: This systematic review was reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. A Literature search was carried out with PubMed and ProQuest databases from 1 January 2010 to 5 October 2020. The outcomes of interest were association of functional dyspepsia with depression and anxiety. The quality of each study was assessed using the Joanna Briggs Institute (JBI) tool.
Results: A total of 13 studies involving 14,076 subjects were included in this review. Almost all of the studies showed that prevalence of depression or anxiety is higher in patients with FD compared to controls. This is implied by a higher mean score on the depression and anxiety questionnaire assessment tools or a positive correlation in the odds ratio. FD is known to affect more females than males, but psychological links were stronger in males. Moreover, prevalence of depression and anxiety symptoms in patients with refractory FD (63.3% and 61.5%) was higher compared to non-refractory FD (20.9% and 23.3%) and healthy patients (10% and 10%).
Conclusion: There is a significant association of FD with depression and anxiety. Thus, identifying psychological factors in FD patients is essential to help clinicians determine the best choice of treatment and improve the prognosis and quality of life of the patients.
Discursos de docentes costarricenses de secundaria sobre la dis/capacidad
Authors: Fernández Fernández Daniel 
Published: May 2021

En este artículo se presenta parte de los resultados de una investigación desarrollada en el Instituto de investigación en Educación de la Universidad de Costa Rica que tiene como uno de sus intereses generales responder a la pregunta: ¿Cuáles son las concepciones que devela el discurso de docentes costarricense de secundaria en torno al tema de la discapacidad? Para responder a esta pregunta, a nivel metodológico, se elaboró un acercamiento de carácter cualitativo en el que se realizaron entrevistas semiestructuradas a docentes de secundaria pertenecientes al ámbito de educación pública costarricense. A partir de dicho material, se desarrolló un análisis discursivo que se basó en un procedimiento de identificación de proposiciones textuales y una elaboración de implicaciones discursivas. Los resultados muestran que la oposición normalidad – anormalidad resulta un elemento clave para comprender las construcciones discursivas del profesorado. De esta forma, se identificaron núcleos discursivos como la idea de la discapacidad como una carga y como una deficiencia, así como otro conjunto de intervenciones que fueron clasificadas como discursos críticos en torno a la diversidad funcional. Una de las principales conclusiones del artículo es que, a pesar de los importantes cambios en materia de legislación y políticas públicas en materia de discapacidad que atañen al ámbito educativo, persisten una serie de concepciones que develan visiones prejuiciadas sobre lo que se entiende por discapacidad. Una posible aplicación del presente artículo es justamente identificar las concepciones estigmatizantes que se vuelven recurrentes, y tomarlas como un punto de partida para establecer un diálogo reflexivo con el profesorado.
First pediatric case of osteomyelitis caused by Robinsoniella peoriensis
Authors: İnal Neşe , Karagöz Alper , Turhan Egemen , Hazirolan Gülşen 
Published: May 2021

Abstract

Robinsoniella peoriensis is a gram-positive, spore-forming, anaerobic rod. In our study, we isolated R. peoriensis from an open fracture of the left distal tibia of a three-year-old male patient. Tissue anaerobic culture was positive for R. peoriensis. It was identified with both matrix-assisted laser desorption ionization time-of-flight mass spectrometry and confirmed via 16S rRNA gene sequencing. The patient responded to ampicillin-sulbactam and amikacin antibiotic therapy. Antimicrobial susceptibility testing should be performed to guide the choice of treatment. To the best of our knowledge, this is the first report of R. peoriensis osteomyelitis in a pediatric patient and first report from Turkey.
Strategi Dinas Penerangan Kodam III/Siliwangi dalam Meningkatkan Citra Positif
Authors: Nuswantoro Gandung , Abidin Yusuf Zaenal , Paryati Paryati 
Published: May 2021

Pendam III/Siliwangi dalam menjalankan tugas adalah menyampaikan informasi secara benar dan profesional. Memberikan tanggapan yang simpatik manakala ada suatu informasi yang dianggap dapat merugikan citra positif Kodam III/Siliwangi. Selain itu sebagai institusi yang sekaligus agen informasi, bertugas mengolah informasi, mengelola informasi, baik untuk pihak internal maupun eksternal. Tujuan dari penelitian ini adalah untuk mengetahui strategi yang dilaksanakan oleh Pendam III/Siliwangi dalam meningkatkan citra positif. Metode penelitian yang digunakan adalah metode studi kualitatif. Adapun teknik pengumpulan data dalam penelitian ini dilakukan dengan wawancara, observasi dan dokumentasi. Kerangka berfikir atau landasan teori yang digunakan dalam penelitian ini, yaitu menggunakan teori strategi yaitu formulasi misi, tujuan dan objektif dasar perusahaan, program dan kebijakan untuk mencapainya dan metode yang diperlukan untuk memastikan bahwa strategi di implementasikan untuk mencapai tujuan-tujuan perusahaan. teori citra di dalamnya terdapat jenis-jenis citra (mirror image, current image, wish image, multiple image). Hasil dari penelitian ini menunjukan bahwa strategi yang dilakukan Pendam III/Siliwangi yaitu melaksanakan program-progam kegiatan dalam rangka untuk meningkatkan citra positif. Dalam meningkatkan citra memperhatikan unsur citra yaitu (mirror image, current image, wish image, multiple image) sebagai acuan meningkatkan citra positif.
Pendam III/Siliwangi in carrying out the duty is to convey information correctly and professional. Provide sympathetic responses when there is information that is considered to harm the positive image of Kodam III/Siliwangi. In addition, as an institution as well as an information agent, in charge of processing information, managing information, both for internal and external parties. The purpose of this research is to know the strategy implemented by Pendam III/Siliwangi in improving the positive image. The research method used is qualitative study method. The data collection technique in this research is done by interview, observation and documentation. The framework of thinking or the theoretical basis used in this research, which is using strategy theory is mission formulation, objective and basic objective of company, program and policy to achieve it and method needed to ensure that strategy implemented to achieve company goals. image theory in it there are types of images (mirror image, current image, wish image, multiple image). The result of this research shows that the strategy of Pendam III/Siliwangi is to carry out activities programs in order to improve the positive image. In improving the image pay attention to the image element that is (mirror image, current image, wish image, multiple image) as a reference to improve the positive image.
Manajemen Humas dalam Memelihara Citra Perusahaan
Authors: Rimayanti Rimayanti , Ruhiyat Ruhiyat , Rasib Abdul 
Published: May 2021

Tulisan ini menjelaskan tentang proses manajemen humas yang dilakukan oleh humas PT.Pindad (Persero) dalam rangka memelihara citra perusahaan memalui program penerimaan kunjungan industri. Penelitian yang dilakukan menggunakan paradigma konstruktivisme, metode kualitatif dan pendekatan studi kasus yang bertujuan untuk mengetahui proses pemeliharaan citra melalui kunjungan industri secara mendalam dan menyeluruh. Konsep yang digunakan adalah konsep four steps public relations dari Cutlip, Center and Broom, dengan menggunakan teknik pengumpulan data observasi partisipatori pasif, dan wawancara mendalam. Teknis analisis yang digunakan adalah reduksi data dan penyajian data. Hasil dari penelitian ini menunjukan bahwa manajemen yang dilakukan oleh Humas PT.Pindad (Persero) dalam mengelola program kunjungan industri memiliki pengaruh terhadap pemeliharaan citra yang dilakukan oleh perusahaan dan sesuai dengan konsep four steps public relations dari Cutlip, Center and Broom yakni proses perencanaan dengan menetapkan tujuan, melakukan operasionalisasi persuratan, menyiapkan tempat, membuat schedule dan rundown acara dan melakukan briefieng. Proses implementasi dengan melakukan pemaparan materi dan plant tour. Proses evaluasi beserta pencarian data dan fakta dengan mewawancarai pengunjung dan evaluasi tahunan perusahaan.
This paper describes the public relations management process carried out by public relations of PT. Pindad (Persero) in order to maintain the company's image through the industrial visit acceptance program. The research was conducted using the constructivism paradigm, qualitative methods and case study approaches that aim to find out the image maintenance process through in-depth and comprehensive industrial visits. The concept used is the concept of four steps public relations from Cutlip, Center and Broom, using passive participatory observation data collection techniques, and in-depth interviews. The analysis technique used is data reduction and data presentation. The results of this study indicate that the management carried out by Public Relations PT.Pindad (Persero) in managing industrial visit programs has an influence on image maintenance carried out by the company and in accordance with the concept of four steps public relations from Cutlip, Center and Broom namely the planning process by setting purpose, operationalize correspondence, prepare a place, make a schedule and rundown of the event and do a briefieng. The implementation process is by presenting material and plant tour. The evaluation process along with data and fact searches by interviewing visitors and annual evaluations of the company.
Kampanye Bank Indonesia dalam melawan Hoax mengenai Rupiah Emisi 2016
Authors: Rinaldi Aldi , Astuti Dyah Rahmi , Amin Dang Eif Saiful 
Published: May 2021

ABSTRAK
Kampanye PR merupakan hal yang penting dilaksanakan oleh humas dalam sebuah organisasi, karena dengan kegiatan tersebut organisasi dapat mengenalkan suatu hal dengan tujuan tertentu. Humas Bank Indonesia melakukan sebuah kegiatan kampanye PR yang unik dan menarik dalam upaya mengenalkan uang Rupiah tahun emisi 2016, peneliti tertarik melakukan penelitian ini dengan tujuan untuk mengetahui bagimana proses yang dilaksanakan oleh humas Bank Indonesia Jawa Barat dalam melaksanakan dan memilih strategi yang tepat dalam memberikan informasi lengkap mengenai ciri-ciri keaslian uang. Penelitian ini menggunakan metode penelitian studi kasus yang berusaha menggambarkan kegiatan melalui pertanyaan penelitian yaitu, pertama bagaimana perencanaan kampanye PR, selanjutnya adalah bagaimana pelaksanaan kegiatan kampanye PR tersebut dan terakhir adalah mengapa humas menjadikan hasil penyebaran informasi sebagai indikator keberhasilan dan evaluasi kegiatan Kampanye ciri-ciri keaslian uang rupiah tahun emisi 2016. Berdasarkan data penelitian kegiatan Kampanye ini melewati berbagai macam tahapan, yang pertama tahap perencanaan yang terdiri dari penentuan anggaran kegiatan,narasumber dan tujuan yang ingin dicapai dalam kegiatan Kampanye tersebut, kedua adalah tahapan pelaksanaan yang diberikan kepada sumber daya yang telah dipilih dan diberikan pelatihan khusus agar saat melakukan kegiatan kampanye dapat memberikan informasi yang menyeluruh, ketiga merupakan proses menilai keberhasilan dan evaluasi kegiatan.
ABSTRACT
Campaign pr it is important to carry out by public relations in an organization, as by these activities organization can introduce a thing with a certain goal. Public relations of bank Indonesia conduct a unique and interesting activity of the PR campaign in an effort to introduce rupiah currency 2016 emission, researcher interested to do this research for the purpose of knowing how the process carried out by public relations officer of Bank Indonesia West Java of implementing and choosing a proper strategy in providing a complete information about the characteristics of the authenticity money. This research uses a study of case method that tries to describe activities through questions of research, first is how to planning pr campaign, next is how the activities of pr campaign and last is why public relations officer made the results of the information dissemination as an indicator of success and evaluation activities of characteristics the authenticity money rupiah campaign 2016 emission. Based on the research data of this Campaign activity through various phases, the first is the planning phase which consists of determining the budget of activities, the source of information and purpose to be achieved in the activities of campaign, second is the implementing phase given to the selected resources and given special training so when carrying out campaign activities can provide comprehensive information, the third is the process of assessing the success and evaluation of activities
Strategi DKM Masjid Raya PT. Dirgantara Indonesia dalam Optimalisasi Kegiatan Keagamaan
Authors: Hartati Ida , Anwar Saeful , Marfuah Lukluk Atin 
Published: May 2021

Penelitian ini bertujuan untuk mengetahui strategi perencanaan, strategi pengorganisasian, dan strategi evaluasi DKM Masjid Raya Habiburrahman PT. Dirgantara Indonesia dalam optimalisasi kegiatan keagamaan. Adapun metode penelitian yang digunakan adalah metode deskriptif dengan pendekatan kualitatif. Pengumpulan data dilakukan dengan menggunakan teknik observasi, studi dokumentasi, wawancara, dan studi kepustakaan. Berdasarkan hasil penelitian di Masjid Raya Habiburrahman, strategi DKM dalam optimalisasi kegiatan keagamaan yaitu dalam strategi perencanaan dilaksanakan dengan membuat rencana kerja yang disebut dengan Garis-garis Besar Haluan Program. Strategi pengorganisasian yang diterapkan adalah dengan melibatkan karyawan PTDI untuk menjadi pengurus DKM. Kemudian strategi evalusi yang diterapkan yaitu melaksanakan rapat evaluasi rutin untuk mengetahui program kerja yang dilaksanakan dan keberhasilan penerapan strategi yang diterapkan. Dalam penelitian ini, dapat disimpulkan bahwa strategi DKM dalam optimalisasi kegiatan keagamaan berhasil diterapkan.
This study aims to determine how the planning strategy, organizing strategy, and evaluation strategy of the DKM Habiburrahman in optimizing religious activities. The research method used is descriptive method with a qualitative approach. In collecting data, it is done by using observation techniques and interviews. Based on the results of research, the DKM strategy in optimizing religious activities, namely in the planning strategy, is implemented by making a work plan called GBHP. The organizing strategy adopted was to involve PTDI employees to become DKM. Then the evaluation strategy that is applied is to carry out routine evaluation meetings to determine the work program of implementing the strategy applied. In this study, DKM strategy in optimizing religious activities was successfully implemented.
Long-chain non-coding RNA n337374 relieves symptoms of respiratory syncytial virus-induced asthma by inhibiting dendritic cell maturation via the CD86 and ERK pathway
Authors: Sun Shuning , Yao Ming , Yuan Lifen , Qiao Jianou 
Published: May 2021

Background: In this study, we investigated the relationship between long-chain non-coding RNAs (lncRNAs) and respiratory syncytial virus (RSV)- exacerbated asthma.
Methods: Transcriptome microarray was used to detect differentially expressed lncRNAs in dendritic cells (DCs) co-cultured with RSV-infected human airway epithelial cells and DCs infected with RSV. The identified downregulation of lncRNA n337374 was validated using fluorescence RT-qPCR. LncRNA n337374-overexpressing DCs and RSV-exacerbated asthmatic mouse models were established. Airway hyperreactivity and bronchoalveolar lavage fluid (BALF) were examined, and pathological changes in lung tissues were observed in mice. Surface molecules in DCs were detected by flow cytometry and RT-qPCR and the expression of CD86 and mitogen-activated protein kinases was determined by western blot.
Results: In an RSV-exacerbated asthmatic mouse model, the airway wall was thickened, luminal stenosis was observed, a large number of inflammatory cells were infiltrated in the lung tissue, lung function was impaired, and counts of inflammatory cells in the BALF were increased. The overexpression of lncRNA n337374 ameliorated these pathological changes and improved impaired lung function and inflammation in an asthmatic mouse model. In DCs co-cultured with RSV-infected human airway epithelial cells, CD86 expression was promoted and ERK was markedly phosphorylated. When lncRNA n337374-overexpressing DCs were used in the co-cultures, the expression of CD86 and phosphorylated ERK was decreased.
Conclusion: The results suggest that lncRNA n337374 overexpression may suppress DC maturation by downregulating the CD86 and ERK pathway, subsequently relieving the symptoms of RSV-induced asthma. LncRNA n337374 may be a promising target in the treatment of RSV infection-induced asthma.
Evidence of Splanchnic-Brain Signaling in Inhibition of Ingestive Behavior by Middle Molecules
Authors: MAMOUN ABDEL-HAFIZ , SÖDERSTEN PER , ANDERSTAM BJÖRN , BERGSTRÖM JONAS 
Published: May 2021

Abstract.
Anorexia, nausea, and vomiting are common symptoms of uremic intoxication. Fractions in the middle molecule weight range, isolated from normal urine and uremic plasma ultrafiltrate, inhibit ingestive behavior in the rat. To investigate their site of action and specificity, male rats were injected intraperitoneally, intravenously, or intracerebroventricularly with concentrated fractions of uremic plasma ultrafiltrate or normal urine (molecular weight range: 1.0 to 5.0 kD) and tested for ingestive and sexual behavior. An intraperitoneal injection of 0.5 ml of urine fraction (10:1) or 2.0 ml of uremic plasma ultrafiltrate fraction (25:1) inhibited carbohydrate intake by 76.3 and 45.9%, respectively, but an intravenous injection had no effect. However, intravenous injection of higher doses inhibited carbohydrate ingestion. An intracerebroventricular injection of 5 or 10 μl of urine (20:1) middle molecule fraction inhibited carbohydrate intake by 13.4 and 41.6%, respectively. An injection of 5 or 10 μl of uremic plasma ultrafiltrate (125:1) middle molecule fraction inhibited carbohydrate intake by 22.6 and 49.5%, respectively. Injections of the corresponding fraction from normal plasma ultrafiltrate had no effect. Injection of urine or uremic plasma ultrafiltrate middle molecule fractions did not affect the display of sexual behavior. These results suggest that middle molecule fractions from uremic plasma ultrafiltrate or normal urine act in the splanchnic region and/or brain to inhibit food intake and that the effect is specific for ingestive behavior.
Acute Renal Impairment after Immersion and Near-Drowning
Authors: SPICER S. TIMOTHY , QUINN DAVID , NYI NYI NYEIN N. , NANKIVELL BRIAN J. , HAYES JAMES M. , SAVDIE ELLIOTT 
Published: May 2021

Abstract.
Acute renal impairment (ARI) secondary to immersion and near-drowning is rarely described and poorly understood. A retrospective case-control study was performed: (1) to determine the incidence of ARI associated with near-drowning or immersion and (2) to define the clinical syndrome and to assess clinical predictors of ARI. Of 30 patients presenting after immersion or near-drowning, 50% were identified with ARI, with a mean admission serum creatinine of 0.24 ± 0.33 mmol/L (2.7 ± 3.7 mg/dl). These patients were a heterogeneous group: Eight had mild reversible ARI, three had ARI related to shock and multisystem failure, two had rhabdomyolysis-related ARI, and two had severe isolated ARI. Two patients required supportive hemodialysis and two died. Patients with ARI experienced more marked acidosis than control patients, as measured by serum bicarbonate (P < 0.001), pH (P < 0.001), and base excess (P < 0.001). There was also a higher admission lymphocyte count in the ARI group (P = 0.056). Dipstick hematuria on admission was significantly more common in patients with ARI (P = 0.016), and patients with 2 to 3+ of admission dipstick proteinuria had a higher peak serum creatinine than patients with less proteinuria (P < 0.05). Admission predictors of ARI by univariate logistic regression analysis included reduced serum bicarbonate (P = 0.002), pH (P = 0.001), and base excess (P < 0.001). The best predictor of ARI on multivariate analysis was a negative base excess (P = 0.01). In summary, acute renal impairment commonly occurs after immersion and near-drowning and is a heterogeneous condition. Although mild reversible renal impairment (serum creatinine < 0.30 mmol/L) (3.4 mg/dl) is usual, severe acute renal failure requiring dialysis can occur. It is recommended that any patient who presents after near-drowning or immersion should be assessed for potential ARI by serial estimations of serum creatinine, particularly when there is an increase in the initial serum creatinine, marked metabolic acidosis, an abnormal urinalysis, or a significant lymphocytosis.
Evidence of a Role for Ki-RAS in the Stimulated Proliferation of Renal Fibroblasts
Authors: SHARPE CLAIRE C. , DOCKRELL MARK E. C. , SCOTT RIZALDY , NOOR MAZHAR I. , COWSERT LEX M. , MONIA BRETT P. , HENDRY BRUCE M. 
Published: May 2021

Abstract.
Progressive renal fibrosis is driven by a range of cytokines that act via membrane receptors and intracellular signaling cascades to evoke gene transcription events and related responses. The Ras family of GTPases has been implicated in many of these signaling cascades in model systems such as 3T3 fibroblasts. However, the role of the specific Ras isoforms Ki, Ha, and N in the stimulation of renal fibroblasts has not been defined. In this study, Ras has been inhibited in primate renal fibroblasts (vero cells) using specific phosphorothioate oligodeoxynucleotides (oligos) targeting the three isoforms. Lipofectin transfection with 200 to 400 nM Ki-Ras oligo inhibited the epidermal growth factor- and fibroblast growth factor-stimulated proliferation of vero cells by 25 to 35% with a lesser effect on serum-stimulated growth. Oligos against Ha-Ras and N-Ras were inactive with respect to control oligo. Total cellular Ras protein (estimated by Western blotting) was reduced by 60 to 90% 24 h after transfection with Ki-Ras oligo. N-Ras, Ha-Ras, and control oligos were inactive. Total Ras synthesis over 4 h measured using [35S]-cys/met pulse chase was reduced by approximately 70% by Ki-Ras oligo and not altered by other oligos. The fractional prenylation of Ras was quantified from the discrete bands on polyacrylamide gel electrophoresis and was increased by the Ki-Ras oligo alone. These data demonstrate that these renal fibroblasts predominantly express the Ki isoform of Ras and that this GTPase plays a role in the stimulated proliferation of these cells. Ras GTPases may be a target for the inhibition of processes leading to renal fibrosis.