bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of denosumab in the complex treatment of giant cell tumor of the spine: reducing of local recurrence rate, surgery time and blood loss
Authors: Tararykova Anastasia Alekseevna , Fedenko Aleksandr Aleksandrovich , Musaev Elmar Rasimogly , Valiev Aslan Kamraddinovich , Kabardaev Ruslan Magomedovich , Borzov Kirill Aleksandrovich , Melnikova Valeria Igorevna 
Published: December 2021

Objective. To assess the effect of the combined treatment method including preoperative denosumab therapy on the results of treatment of patients with giant cell tumors of the spine.Material and Methods. A single-center retrospective-prospective study of a series of clinical cases included 15 patients with giant cell tumors of vertebrae. The average follow-up period was 56 months. A total of 11 patients received denosumab therapy according to the following scheme: 120 mg subcutaneously on the 1st, 8th, 15th and 28th days of the first month and then once every 28 days. Surgical options included marginal resection, segmental resection, or en-bloc resection with or without spinal reconstruction/stabilization. In the case of locally advanced and inoperable disease, long-term therapy with denosumab was carried out until the disease progressed or serious adverse events appeared.Results. Thoracic vertebrae were involved in 7 (46.6 %) of 15 cases, lumbar in 4 (26.7 %) and cervical in 4 (26.7 %). Local recurrence rate after surgery alone was 40 % (2/5), average time to recurrence onset was 4.5 months. No relapses were observed after combined treatment performed in four patients. Disease progression during long-term denosumab therapy for inoperable disease recurrence was not recorded (0/7). The average number of denosumab injections before surgery and during long-term therapy was 15 and 24 injections, respectively. Denosumab therapy allows reducing the duration of surgery and the volume of blood loss.Conclusion. Combined therapy of giant cell vertebral tumor allows to reduce the risk of recurrence of the disease, as well as to reduce surgery duration and blood loss. Long-term continuous therapy for inoperable cases allows achieving long-term stabilization of the effect. Due to the rarity of giant cell tumors of the spine, a further prospective recruitment of patients is required to study the efficacy and safety of combined therapies.
Valorization of birch bark using a low transition temperature mixture composed of choline chloride and lactic acid
Authors: Jablonský Michal , Šima Jozef , Strižincová Petra , Hroboňová Katarína , Majová Veronika , Ház Aleš 
Published: December 2021

Abstract
This article presents the results obtained in the extraction of birch bark with a green solvent. A low transition temperature mixture (LTTM) consisting of choline chloride (ChCl) and lactic acid in a molar ratio of 1:1 was used as the solvent. Extraction was performed at 60°C and 80°C. At both temperatures, the effect of extraction time on the yield of the extracted substances was monitored. The yields reached were compared with those obtained in studies using common solvents such as ethanol, methanol, d-limonene, ethyl acetate, and others. The extract was quantitatively analyzed by HPLC-UV to determine betulin and betulinic acid (0.491–1.788 mg/g dry bark and 0.106–0.316 mg/g dry bark, respectively). Total phenolic content was determined spectrometrically using Folin–Ciocalteu reagent and expressed as Gallic acid equivalents (GAE; 18.6–56.8 mg GAE/g dry bark). This study has shown that extraction with a green solvent composed of ChCl and lactic acid can be an effective method for extracting polyphenolic compounds from birch bark. The process for extracting triterpenes (betulin and betulinic acid) is less suitable compared to conventional methods using the mentioned organic extractants.
Changed Industrial Relationship by Offshoring Threat and Labor Share: An Empirical Game-Theoretic Analysis
Authors: Tamura Tetsuya , Tokumaru Natsuka 
Published: December 2021

Abstract
Research indicates that the labor share of the aggregate income has decreased steadily since the mid-1970s, i.e. when the globalization process began. This paper discusses the ways in which qualitative changes in globalization, coupled with increased offshoring, have changed industrial relationships. In our analysis, we consider a simple Nash bargaining model between employers and employees. Our model proposes the hypotheses that employees gain the power to increase their wages when employers do not have the option of offshoring. However, employees typically lose this power when employers possess an offshoring threat, culminating in wage deduction. Leveraging a panel set of data obtained from 18 OECD countries during the period 1975–2017, we have empirically confirmed these hypotheses by comparing the first phase of globalization—not characterized by an offshoring threat—with the second phase, which entails an offshoring threat. Our findings reveal that workers’ bargaining power, positively affects labor share in the first phase; however, it loses its effect in the second phase when offshoring exerts its negative effects on labor share. We conclude that a qualitative change in globalization with increased offshoring radically changed industrial relationship through the threat effect.
On the oscillation of nonlinear delay differential equations and their applications
Authors: Bazighifan Omar , Askar Sameh 
Published: December 2021

Abstract
The oscillation of nonlinear differential equations is used in many applications of mathematical physics, biological and medical physics, engineering, aviation, complex networks, sociophysics and econophysics. The goal of this study is to create some new oscillation criteria for fourth-order differential equations with delay and advanced terms

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The method is based on the use of the comparison technique and Riccati method to obtain these criteria. These conditions complement and extend some of the results published on this topic. Two examples are provided to prove the efficiency of the main results.
Fabrication and Characterization of the Electrospun Polyvinyl Alcohol Nanofibers Incorporated with the Extracted Fruit Peel Pectin and Zinc Oxide Nanoparticles
Authors: Banitaba Seyedeh Nooshin , Khoshnama Arezou , Poursharifi Nazanin , Nasari Mina , Semnani Dariush , Jafari Maryam 
Published: December 2021

Abstract
Herein, pomegranate, orange, and cantaloupe peel pectins were extracted. Then, nanofibrous membranes of polyvinyl alcohol (PVA)/pectin with various ratios (70:30, 80:20, and 90:10) were fabricated by using a standard electrospinning procedure. In the next step, various concentrations of zinc oxide (ZnO) nanofiller were introduced into the PVA/pectin electrospun fibers. Finally, the effects of pectin and ZnO ratios on morphology and mechanical characteristics of the electrospun fibers were evaluated. Based on the scanning electron microscopy images, thinner fibers were formed by an increase of the pectin and ZnO proportions in the electrospun fibers. According to the obtained Fourier-transform infrared spectroscopy (FTIR), all extracted pectins were high methoxy. In addition, complexation between the PVA polymer chains, extracted pectins, and ZnO particles was confirmed by FTIR spectra. Moreover, increase of the pectin and ZnO ratios led to fabrication of fibers with superior mechanical strength and lower strain.
Optimalisasi Pengereman Regeneratif dengan Perubahan Sudut Eksitasi pada Pulsa Tunggal
Authors: Kusumaningrum Nazila , Riyadi Slamet , Pratomo Leonardus Heru , Setyawan Florentinus Budi 
Published: December 2021

Most of the energy is wasted into heat energy due to conventional braking, so an optimal braking strategy is needed. A Regenerative braking utilizes the kinetic energy of the engine into electrical energy by changing the function of an electric machine into a generator. The regenerative braking system uses a Switched Reluctance Machine (SRM) which has several advantages; simple construction, does not require maintenance, and return energy to the battery. The method that can be used in the regenerative braking system of the SRM is the change of excitation angle to produce the maximum peak phase current. This study aims to optimize regenerative braking by changing the angle (Î¸eks) using simple controls to produce energy that is greater than the battery voltage so that current may flow to the battery when braking occurs. The results of the analysis for method implementation were proven by testing the devices in the laboratory. Â Based on the results of the tests, the exact angle was obtained, namely the value of Î¸eks = 20Âº and the value of Î¸kom = 170Âº with an initial speed of 1822 RPM, reduced into 1522 RPM by braking process, which could produce a peak current of 12,5 A and a current flowing to the battery was 5A.
Q fever and early pregnancy failure: a Scottish case–control study
Authors: Wheelhouse Nick , Kemp Sadie , Halliday Jo E B , Tingas Efstathios Alexandros , Duncan W Colin , Horne Andrew W 
Published: December 2021

Lay summary
Q fever is a bacterial disease that passes between animals and humans and causes disease in both. The disease has been associated with pregnancy complications including miscarriage. This study was undertaken to identify if Q fever exposure was correlated with miscarriage in 369 women attending a pregnancy support unit in Edinburgh. The women in the study were in two groups, the miscarriage group with 251 women who had experienced a miscarriage and a control group of 118 women who had not experienced miscarriage. Three women were found to be positive for Q fever antibodies, suggesting that they had previously been exposed to the infection and all of them were from the group who had experienced miscarriage. The study indicates that Q fever is relatively rare in women attending an urban Scottish hospital suggesting that the infection is not a major cause of miscarriage in this population. However, as Q fever antibodies could only be found in women within the miscarriage group, it suggests that the infection cannot be ruled out as a potential cause of miscarriage in individual cases.
CHEMOPREVENTION OF HUMAN PROSTATE CANCER BY ORAL ADMINISTRATION OF GREEN TEA CATECHINS: A TRANSLATIONAL RESEARCH STORY
Authors: Bettuzzi S , Rizzi F 
Published: December 2021

Clinical progression of Prostate Cancer (CaP) is variable: some tumours are indolent, others
rapidly progress. Because, diagnosis is usually in elderly men, CaP is an ideal target for
chemoprevention. We showed that Green Tea Catechins (GTC) possess anti-tumour activity,
suggesting that it might be beneficial in the early stages of cell transformation. But an experimental
confirmation in a real clinical setting was needed. High-Grade Prostatic Intraepithelial Neoplasia
(HGPIN) is a pre-invasive stage of CaP for which no treatment options are available until CaP is
diagnosed.
The Low Productive Soils from Dolj District and Their Main Features
Authors: POPESCU Cristina , VASILE D. , GRECU Florina 
Published: December 2021

Due to the heterogenous natural conditions on the Dolj District there were formed an array of soils from the sandy ones to the luvic and stagnogleic ones. The sandy soils that were formed under the influence of Danube River occupy large surfaces on the south western part of the Dolj District and have a high content of basic elements and have a somehow higher fertility than the ones formed on the jiu valley. Generally, the sandy soils from Dolj District have a low fertility status determined by the higher thick material content, higher water permeability and reduced mineral elements content.
The salty soils are present within the Jiu lowland and Danube lowland as discontinuous surfaces where the watertable is shallow. In this zones, along with solonetz and solonceak are encountered on smaller surfaces alluvial soils as salty ones that are low to average salinisated.
The luvosoils occupies the plateau zone of the dolj District, within the low zones where the water logs a longer period during the year determining eluviation phenomena as well as stagnogleisation of the shallow soil profile and helps creating a not quite favorable environment for plant growing.
The reddish preluvosoils and stagnogleisated ones are encountered especially on the northern zone of the district on the plateau that have no drainage where the water logging determines eluviation processes and stagnogleisation, especially on the upper soil profile.
Generally, within the northern part of the district the soils from the slopes have different erosion degrees that determine the decreasing of their fertility.
The Influence of the Fertilization System and of Soil and Climate Conditions on Maize Yield
Authors: SALA Florin , RADULOV Isidora , CRISTA F. , BERBECEA Adina 
Published: December 2021

Starting from frequently encountered situations regarding the restrained structure of cultivated plants and simple crop rotations in different agricultural exploitations in the Banat Plains, we tested the influence of mineral fertilisation on maize culture with the purpose of enhancing biomass yield both total and useful in that culture. The effect of fertilisers was tracked both from the standpoint of the unilateral influence of nitrous, phosphorus and potassium fertilisers as well as complex, correlated with the soil and climate conditions.
Yield increases were between 185,0 kg/ha (P50K50) and 7420,75 kg/ha (N200P150K150) compared to the control variant and the level of intensifying of the yield process through fertilisation can be established for each agricultural exploitation compared to the technical-economical conditions and the agricultural system used.
The Valuation of Romania Agriculture in the European Context of Sustainable Development through Data Envelopment Analysis
Authors: BURJA Camelia , BURJA Vasile 
Published: December 2021

Romanian agriculture has a high productive potential owned to the existent agricultural area and to the employed population. The sustainable development of agriculture implies protecting the environment, improving quality of life in the rural area, manufacturing agricultural products based on green principles, but also practicing an efficient and competitive agriculture, based on high economic efficiency. Improving performance and competitiveness targets the efficient use of production factors in accordance with the principles of sustainable development.
Data Envelopment Analysis (DEA) represents an opportunity to assess the performance of socio-economic systems, necessary to justify decisions to allot resources and to rationally establish the objectives in this sector. This method is used by the paper to show the current sustainable development stage of Romanian agriculture compared to the average level recorded by EU agriculture, which represents a goal for Romania for a medium-term time horizon. DEA confirms the information originated from the analysis of statistical indicators regarding the considerable gap between the performances of Romanian agriculture and the ones of the EU concerning the efficient use of land and labour force.
The results of the analysis may serve to justify decisions regarding organizational, technical and economic changes that must be done through the agricultural policy of Romania to increase efficiency and competitiveness in this important sector of the national economy.
Determination of Chemical Composition of Maize by Destructive and Non-Destructive Method
Authors: DALE Laura Monica , ROTAR Ioan , VIDICAN Roxana , MOREA Adriana , MOGOS Alin 
Published: December 2021

Using NIRS technique is an elegant and very precise, this technique become more frequently used for determining physico-chemical properties of feed, especially chemical composition (dry matter, protein, ash, fiber, fat, non-nitrogenous extractive substances. The contents of dry matter, crude protein, crude ash, crude fiber, crude fat, non – nitrogenous extractive substances of maize are determined by destructive methods and then using them was build the calibration curve for NIRS with which we will determine all the chemical properties of the material using prediction.
This paper aims to highlight a way of direct analysis method undestructive of crude protein, crude fat, crude fiber, crude ash, non-nitrogenous extractive substances using near infrared spectrometry technique in conjunction with reflected attenuated total. For each property we have used these method assessment: for the crude protein was used Kjeldahl method, for crude fat was used Soxhlet method, for crude ash performed Hennenberg – Stohmann method, for crude fiber was used Hennenberg - Stohmann method and for non – nitrogenous extractive substances was used mathematical calculation. All these results determined by the classical method, the destructive method, were used to build the calibration curve for device FT-NIR Spectrometer Perkin Elmer Spectrum 100 N with accessory N NIRA. Mathematical model was built using the near infrared spectrofotoscopiei technique in conjunction with multivariable calibration techniques using the Perkin Elmer program Spectrum Quant + 4.60. The method provides a rapid and reliable alternative to traditional quantitative methods for determining which usually requires several hours to complete.
Research on Crude Fat and Crude Fiber Content on Maize Cob and Strains by FT-NIR Spectrum
Authors: DALE Laura Monica , ROTAR Ioan , VIDICAN Roxana , BOGDAN Anca , BUDUREA Gratian 
Published: December 2021

Using Near Infrared Spectrometry has become lately quite a developed technique in the different physico-chemical parameters of the feed as a procedure is extremely elegant and precise use. This paper aims to highlight a way of direct analysis method undestructive crude fat and crude fiber using near infrared spectrometry in conjunction with reflected attenuated total.
Tests were conducted on samples of maize cob and maize strains from The Research - Agricultural Development Turda. Samples done at each variant separately. Each sample was subjected to destructive method, Soxhlet method for determinating the crude fat and Hennenberg - Stohmann for crude fiber and then they were collected with NIR spectrum.
We have built mathematical models for both the cob and strains, based on these techniques and multivariated analysis allows the determination of an error prediction for the best crude fat 0.71% and the crude fiber of 0.34%.
Researches Concerning the Behaviour of Some Different Wheat and Corn Genotypes to Granary Weevil (Sitophilus granarius L.) Attack
Authors: DINUŢĂ Adrian , BUNESCU Horia , DAN Gabriela Teodora , BODIS Ilonka 
Published: December 2021

Taking into account that chemical treatments are generally pollutant, their use in crop protection is generally accepted, but at the same time is subject to narrow limitations in case of stocks used for human and animal consumption.
This paper presents the results of some laboratory tests regarding the resistance of different genotypes - wheat varieties and corn hybrids on the attack of grain weevil (Sitophilus granarius L.) that would help control this pest through ecological methods. Due to the lack of information in the speciality literature worldwide regarding the resistance of stored cereal grains on the attack of grain weevil, we decided to study this aspect thoroughly between 2005-2009, in the Entomology Laboratory at Agricultural Faculty of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca.
The Biodegradative Ability Testing of the Microorganisms Isolated from Oil Contaminated Soils
Authors: DOBOŞ Laura , PUIA Carmen 
Published: December 2021

The bacteria and the fungi are the main microorganisms responsible of biodegradation of hydrocarbons in the oil. In the isolation of bacteria was used soil samples polluted with hydrocarbons. Soils were collected from two oil sites - Ploieşti and the Suplacu de Barcău. There were obtained a number of 41 pure bacterial cultures, on which were analyzed the following aspects: colony forming units, morphological characters (Gram staining and bacterial cell shape) and cultural characters of colonies (shape, pigmentation, gloss, profile, degree of transparency, and edge of colony).
Genera of bacteria identified were: Arthrobacter, Pseudomonas, Bacillus, Flavobacterium, Alcaligenes, Achromobacter, Brevibacterium, Clostridium, Corynebacterium, and Escherichia. Bacterial strains were tested on media with different concentrations of oil, aiming their biodegradation capacity of petroleum hydrocarbons. The microbial consortium was created of bacterial cultures which showed good and very good results, in the terms of their ability in the biodegradation of hydrocarbons.
Analysis of Per Se and Genetic Diversity of Maize Synthetic Populations for Grain Quality: Implications for Breeding
Authors: HAS Voichita , GULEA Alin , HAS Ioan , COPANDEAN Ana 
Published: December 2021

The objective of this research was to determine whether phenotypic and genetic diversity could be identified for maize grain quality traits (percentage of starch, protein, oil, fiber and ash) and agronomic traits. 59 maize synthetic populations which differed in earliness and for geographic origins were evaluated in the field at the Agricultural Research Station Turda - Romania, for their per se value. Each synthetic population was tested only one year and was characterized for their ear characteristics and grain quality attributes. The grain oil and ash content showed high variability among genotypes.
The experiment was conducted over 2 years (2006-2007) and 2 locations (Turda and Targu-Mures). Analysis of variance showed significant differences among the genotypes for all traits studied. General combining ability (GCA) effects were more important for grain content than specific combining ability (SCA). The occurrence of low interactions between synthetic populations and testers for all characters suggested the occurrence of high statistical additive effects expressed whatever the system of population evaluation. These results support breeding effort towards the genetic improvement of grain quality traits in “Turda” maize germplasm.
Short Chain Food Supply in Flanders (Belgium): Direct Sales of Farm Made Products
Authors: HUYGENS Didier , LIPS Dirk , AERTS Stef 
Published: December 2021

During the last decennia, the distance between the producer and the consumer has increased strongly. This enlarged distance manifests in different areas. Firstly, the distance has become larger geographically. Food products are transported around the world and have become common goods. Secondly, the producer and the consumer are driven apart on a social level. Many consumers have never visited a farm and have no idea how their food is produced. Thirdly, the food industry, distribution and the entire agribusiness complex have settled in between producer and consumer, thus enlarging the economical distance.
This system is being criticised from many points of view and opportunities are brought forward that strive towards a more durable process on an ecological level (food kilometres, food transport); an economical level (fair price for both the producer and the consumer, regional economy) and a social level (local contacts, cooperation). A variety of initiatives, both supported by the government and unsupported, are started. It seems that especially in the peri-urban area, being close to both producer and consumer, opportunities exist for short chain initiatives.