bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intrapreneurship in the digital era: driven by big data and human resource management?
Authors: Wan Wenhai , Liu Longjun 
Published: June 2021

PurposeThis study aims to investigate whether big data enabling (BDE) and empowerment-focused human resource management (EHRM) can effectively promote employee intrapreneurship and their effects on platform enterprises’ innovation performance. The paper also examines the contexts under which employee intrapreneurship may affect business performance.Design/methodology/approachData were collected from 155 platform enterprises in China in the form of questionnaires. Participants were mainly middle and senior managers with a comprehensive grasp of the enterprises’ information.FindingsThe results indicated that BDE, EHRM and their synergy positively influenced employee intrapreneurship, which could potentially extend to enterprise performance. Specifically, employee intrapreneurship played a partial mediating role between BDE, EHRM and performance, and a whole mediating role between synergy and performance. Finally, platform strategic flexibility played a positive moderating role between employee intrapreneurship and performance.Practical implicationsPlatform enterprises should focus on the construction and utilization of big data and EHRM to stimulate organizational vitality. They also need to encourage employees to start businesses and build more flexible strategies to adapt to the dynamic economic environment.Originality/valueThis is an empirical study on the effect mechanism of big data and HRM on employee intrapreneurship and platform enterprises’ performance in China. The paper combined big data, HRM and employee intrapreneurship, which broke through the previous research on enterprise entrepreneurship and social entrepreneurship. The findings guide platform enterprises to stimulate organizational vitality and achieve better performance in the digital era.
Automatic sizing functions for unstructured mesh generation revisited
Authors: Liu Zhiwei , Chen Jianjun , Xia Yifan , Zheng Yao 
Published: June 2021

PurposeSizing functions are crucial inputs for unstructured mesh generation since they determine the element distributions of resulting meshes to a large extent. Meanwhile, automating the procedure of creating a sizing function is a prerequisite to set up a fully automatic mesh generation pipeline. In this paper, an automatic algorithm is proposed to create a high-quality sizing function for an unstructured surface and volume mesh generation by using a triangular mesh as the background mesh.Design/methodology/approachA practically efficient and effective solution is developed by using local operators carefully to re-mesh the tessellation of the input Computer Aided Design (CAD) models. A nonlinear programming (NLP) problem has been formulated to limit the gradient of the sizing function, while in this study, the object function of this NLP is replaced by an analytical equation that predicts the number of elements. For the query of the sizing value, an improved algorithm is developed by using the axis-aligned bounding box (AABB) tree structure.FindingsThe local operations of re-meshing could effectively and efficiently resolve the banding issue caused by using the default tessellation of the model to define a sizing function. Experiments show that the solution of the revised NLP, in most cases, could provide a better solution at the lower cost of computational time. With the help of the AABB tree, the sizing function defined at a surface background mesh can be also used as the input of volume mesh generation.Originality/valueTheoretical analysis reveals that the construction of the initial sizing function could be reduced to the solution of an optimization problem. The definitions of the banding elements and surface proximity are also given. Under the guidance of this theoretical analysis, re-meshing and ray-casting technologies are well-designed to initial the sizing function. Smoothing with the revised NLP and querying by the AABB tree, the paper provides an automatic method to get a high-quality sizing function for both surface and volume mesh generation.
Knowledge transfer in technological innovation clusters
Authors: Fioravanti Vania Lopes Simoes , Stocker Fabricio , Macau Flavio 
Published: June 2021

PurposeThe aim of this research is to analyze the knowledge transfer process in technological innovation clusters. The problem of the study addresses how organizations can act in a network to enhance experiences and gains, particularly in the aspect of knowledge management.Design/methodology/approachThe study is qualitative, applied through a case study, cross-sectional and multiple sources of evidence – semistructured interviews, nonparticipant observation and analysis of documents and secondary institutional data. The case analyzed was the Technology Park of São José dos Campos, in Brazil, involving private companies, governmental organizations, universities and research institutions.FindingsThe results reinforce the arguments that the transfer of knowledge is influenced by factors, facilitators or inhibitors such as: cooperation, relationship with institutions, workforce mobility and geographical proximity, influencing the competitiveness and performance of the organizations in the cluster.Research limitations/implicationsThis study advances the knowledge management literature in network environments, especially in technological innovation clusters, systematizing and highlighting the facilitating and inhibiting dimensions of knowledge transfer.Practical implicationsThe present work has a direct dialogue with the managers and actors involved in the governance of these organizational arrangements with regard to increasing the capacity for creation and the dissemination of knowledge among organizations, educational institutions, government and companies.Originality/valueThere is a presence of aspects indicating that knowledge goes beyond borders through dynamic and collaborative structures, reinforcing the premise that clusters must be perceived as an evolutionary system, whose result of interactions leads to a superior joint capacity.
User engagement and self-disclosure on Snapchat and Instagram: the mediating effects of social media addiction and fear of missing out
Authors: Sultan Abdullah J. 
Published: June 2021

PurposeThe present research examines self-disclosure as a negative behavior arising from excessive engagement on social media as well as social media addiction and fear of missing out.Design/methodology/approachA convenience sample of 2,333 Snapchat and Instagram users in Kuwait collected using a snowball sampling procedure was utilized to validate the research model and test the proposed relationships using two-stage structural equation modeling.FindingsA multigroup confirmatory factor analysis across Snapchat and Instagram users showed that the measurement invariance was statistically nonsignificant. In addition, path analysis confirmed both a significant direct relationship between user engagement and self-disclosure and indirect relationships through social media addiction and fear of missing out as mediators.Practical implicationsEthicists and consumer protection agencies must increase public awareness about the danger of overdisclosure of personal information on social media. The desire to be popular like fashionistas and influencers has pushed some young users to expose themselves to the public at extreme levels. Serious steps must be taken to educate young users about the negative consequences of self-disclosure on social media and healthy ways to capitalize their social presence on social media.Originality/valueThis study focuses on Snapchat and Instagram as underexplored social media applications with excessive engagement and potentially negative consequences on society.
Entrepreneurial opportunity recognition: a bibliometric overview and clustering analysis
Authors: Mohammadi Navid , Heshmati Saeed 
Published: June 2021

PurposeEntrepreneurship is the driving force of countries for sustainable economic development. The importance of this issue is to the extent that in recent years, countries have made great efforts to develop their entrepreneurial ecosystem. But the starting point for entrepreneurship is when an opportunity is identified and the entrepreneur rises to use it. Accordingly, opportunity recognition will be the foundation of entrepreneurship and ultimately sustainable development. Given the importance of this topic, this paper attempts to provide a large picture of the studies conducted in this field.Design/methodology/approachGiven the importance of this topic, this paper attempts to provide a large picture of the studies conducted in this field by reviewing 868 articles published on the Web of Science database in the field of opportunity recognition. Accordingly, using statistical descriptions of articles, analyzing the communication network among elements such as authors, countries, institutions, keyword analysis in articles and examining their trends over time, identifying the most important articles using co-citation analysis and finally this macroimage has been mapped, clustered and identified in leading articles in the last decade by co-citation clustering.FindingsThe results of the clustering show that the five main clusters of recent decades have included entrepreneurial characteristics and opportunity recognition, macroeconomic opportunity recognition cluster (community and impact on economic development of the country), opportunity recognition process cluster, opportunity recognition cluster in serial and intra-entrepreneurship and opportunity recognition cluster in new venture internationalization.Originality/valueUsing a bibliometric analysis and co-citation analysis in the field of opportunity recognition and making a big picture of studies in this field of study is a contribution that can be used for future studies and researchers and managers in this field.
Crab antics: the moral and political economy of greed accusations in the submerging Sundarbans delta of India
Authors: Mehtta Megnaa 
Published: June 2021

AbstractThe livelihood of crab collecting, practised for generations in the Sundarbans forest of India, has undergone a radical moral makeover in recent years. Largely landless crab fishers are now the subject of frequent public denunciations by local authorities for their supposed greed and reckless endangerment of the entire ecosystem. While greed and its related category of need emerge from a local moral ecology of the region, internationally funded conservation campaigns and recent disruptions in the global crab supply chain reveal how accusations are activated and the means through which they play out amidst pre‐existing village hierarchies. This article accounts for the political, economic, and moral shifts that underpin these accusations. In counterpoint, I present the defences of the accused, and explore crab collectors’ notions of a sufficient life and the rich moral distinctions they themselves make between greed (lobh), need (aubhav), desire (chahida), and habit (swabhav). I then step back to show the broader political contours that shape the discourse of ‘greedy’ crab collectors. I argue that both the conservation movement and allied state actors have distorted the material and moral resources intended to combat climate change and other environmental threats by scapegoating the politically disenfranchised: local fishers. Powerful stakeholders, as a result of their own political impotency, are deployed in a game of crab antics that fails to address the underlying environmental catastrophe while displacing the psychic burden of greed onto the poor.
Choice of basal insulin therapy is associated with weight and height development in type 1 diabetes: A multicenter analysis from theGerman/Austrian DPVregistry in 10 338 children and adolescents
Authors: Vollbach Heike , Auzanneau Marie , Reinehr Thomas , Wiegand Susanna , Schwab Karl‐Otfried , Oeverink Rudolf , Froehlich‐Reiterer Elke , Woelfle Joachim , De Beaufort Carine , Kapellen Thomas , Gohlke Bettina , Holl Reinhard W. 
Published: June 2021

AbstractBackgroundAvailable basal insulin regimes differ in pharmacokinetic profiles, which may be related to subsequent changes in anthropometry in patients with type 1 diabetes. This analysis elucidates the standardized height and body mass index development (height and BMI standard deviation score [height‐SDS and BMI‐SDS]) in pediatric type 1 diabetes patients depending on the choice of basal insulin.MethodsLongitudinal data of 10 338 German/Austrian patients from the Diabetes Prospective Follow‐up (DPV, Diabetes Patienten Verlaufsdokumentation) database were analyzed. Patients aged 5.0 to 16.9 years were treated exclusively with neutral protamine Hagedorn (NPH), insulin detemir (IDet), insulin glargine (IGla), or continuous subcutaneous insulin infusion (CSII) for at least 3 years. Population‐based German reference data were used to calculate height‐SDS and BMI‐SDS. Multiple linear regression was conducted.ResultsBMI‐SDS increased significantly in all regimes (NPHP = .0365; IDetP = .0003; IGlaP < .0001; and CSIIP < .0001). Direct comparison of the therapies revealed a favorable association only for NPH vs IGla. A rise in BMI‐SDS was observed for all insulins in females, but only for IGla in males. BMI‐SDS increment was not observed before 8 years of age.Initially and at the end of the observation period, mean height was above the 50th percentile of the reference population. Across the cohort, height‐SDS declined during the observation period, except for CSII. Apart from the 5.0‐ to 7.9‐year‐old subgroup, long‐acting insulin analogues were associated with a significant loss of height‐SDS.ConclusionsChoice of basal insulin regimen might influence height development. CSII appeared to have a favorable effect on growth trajectories. All therapies were associated with an increase of BMI‐SDS, most evident in females.
Referral and uptake of services by distressed callers to the Cancer Council Information and Support telephone service
Authors: Taylor Jo , Fradgley Elizabeth A. , Clinton‐McHarg Tara , Hall Alix , Paul Christine L. 
Published: June 2021

AbstractBackgroundPatient‐centered cancer care includes emotional, informational, and practical support that is personalised to the needs of patients and inclusive of family and friends. However, when supportive care referrals are offered in hospital settings, distressed patients and carers do not consistently act on those referrals, which can prolong patient suffering. The degree to which sub‐optimal referral uptake also occurs in Australian telephone support services is unknown.AimsTo report, among a sample of distressed patients and caregivers who called a cancer information and support service: 1) the types of services used; 2) proportion who received and actioned a referral (uptake); 3) associations between referral to a service and callers’ characteristics); and, 4) associations between uptake of a referred service and callers’ characteristics.MethodsThis study used cross‐sectional data collected at 3‐month post‐baseline from control participants (usual care group) enrolled in the Structured Triage and Referral by Telephone (START) trial. The START trial recruited distressed adult cancer patients and caregivers from the Cancer Council Information and Support Service (CIS). A research assistant conducted a 30–45 min telephone interview with participants, which included recall of referrals provided by CIS staff and reported uptake of referral(s) to the offered service types.ResultsMost patients (98%) and caregivers (97%) reported receiving a referral to a service. For patients and caregivers respectively, information materials (71%, 77%), CIS call‐back (51%, 43%), practical services (52%, 45%), and group peer support (49%, 51%) were the services most frequently offered. For callers receiving a referral, uptake was highest for information materials (91%) and CIS call‐backs (89%) and lowest for specialist psychological services (30%). Significant association was found between older age and reduced uptake of services (p = 0.03).ConclusionThe high uptake rate of CIS call‐backs suggests it is a potentially more acceptable form of support compared to specialist psychological services. Efforts to reduce the barriers to telephone‐based psychological services are required. Specifically, older age peoples’ and caregivers’ preferences for support and priorities who may benefit from a referral coordinator.
Analysis of outcomes of biliary reconstruction after post‐cholecystectomy bile duct injuries
Authors: Anand Utpal , Kumar Ramesh , Priyadarshi Rajeev Nayan , Kumar Manoj , Kumar Rakesh , Ahmed Nehal , John Aaron George , Parasar Kunal , Kumar Bindey 
Published: June 2021

AbstractBackgroundPost‐cholecystectomy bile duct injury (BDI) is a serious complication that often requires surgical repair. This study aimed to analyze the outcomes of surgery performed for BDI and to determine the factors associated with post‐surgical complications.MethodsA retrospective analysis was conducted using a prospectively maintained database of 105 patients who underwent surgical repair for post‐cholecystectomy BDI between March 2013 and March 2020. BDI was classified based on the Strasberg‐Bismuth system, and the outcomes were graded using the McDonald criteria. Multivariable logistic regression was used to identify the significant variables associated with postoperative complications.ResultsIn a cohort of 105 patients with post‐cholecystectomy BDI who underwent bilioenteric repair, 71 (67.6%), 25 (23.8%), 2 (1.9%), and 7 (6.7%) patients had excellent, good, fair, and poor outcomes, respectively, during a median follow‐up of 64 months. The incidence of recurrent biliary stricture after definitive surgical hepaticojejunostomy was 6.7% (n = 7). The presence of cholangitis, choledochoduodenal fistula, and hilar biliary strictures was among the significant variables associated with the development of both short‐term and long‐term complications following surgery.ConclusionsSurgical repair of BDIs with bilioenteric anastomosis can yield excellent results when managed in a tertiary care center where expertise in the reconstruction of the biliary tree is prioritized.
Forecasting the old‐age dependency ratio to determine a sustainable pension age
Authors: Hyndman Rob J. , Zeng Yijun , Shang Han Lin 
Published: June 2021

SummaryWe forecast the old‐age dependency ratio for Australia under various pension age proposals, and estimate a pension age scheme that will provide a stable old‐age dependency ratio at a specified level. Our approach involves a stochastic population forecasting method based on coherent functional data models for mortality, fertility and net migration, which we use to simulate the future age‐structure of the population. Our results suggest that the Australian pension age should be increased to 68 by 2030, 69 by 2036 and 70 by 2050, in order to maintain the old‐age dependency ratio at 23%, just above the 2018 level. Our general approach can easily be extended to other target levels of the old‐age dependency ratio and to other countries.
Prediction of maternal and fetal pharmacokinetics of indomethacin in pregnancy
Authors: Pillai Venkateswaran C. , Shah Mansi , Rytting Erik , Nanovskaya Tatiana N. , Wang Xiaoming , Clark Shannon M. , Ahmed Mahmoud S. , Hankins Gary D. V. , Caritis Steve N. , Venkataramanan Raman 
Published: June 2021

AimsIndomethacin is used for the treatment of preterm labour, short cervices and idiopathic polyhydramnios during pregnancy. Few studies have described the pharmacokinetics (PK) of indomethacin during pregnancy. This study aimed to determine maternal and fetal PK of indomethacin during different trimesters of pregnancy using physiologically based PK (PBPK) modelling and simulations.MethodsFull PBPK simulations were performed in nonpregnant subjects and pregnant subjects from each trimester of pregnancy at steady state using Simcyp's healthy volunteers and pregnancy PBPK model, respectively. The fetal exposures were predicted using a fetoplacental pregnancy PBPK model. The models were verified by comparing PBPK‐based predictions with observed PK profiles.ResultsPredicted exposure (AUC0‐6h) and clearance of indomethacin in nonpregnant women and pregnant women are similar to the clinical observations. AUC0‐6h of indomethacin is approximately 14, 24 and 32% lower, consistent with 18, 34 and 52% higher clearance in the first, second and third trimesters of pregnancy, respectively, compared to nonpregnant women. Predicted fetal plasma exposures increased by approximately 30% from the second trimester to the third trimester of pregnancy.ConclusionA mechanistic PBPK model adequately described the maternal and the fetal PK of indomethacin during pregnancy. As the pregnancy progresses, a modest decrease (≤32%) in systemic exposures in pregnant women and a 33% increase in fetal exposures to indomethacin were predicted. Higher fetal exposures in the third trimester of pregnancy may pose safety risks to the fetus. Additional studies are warranted to understand the exposure–response relationship and provide appropriate dosing recommendations during pregnancy that consider both safety and efficacy.
NKG2D defines tumor‐reacting effector CD8+ T cells within tumor microenvironment
Authors: Mojic Marija , Shitaoka Kiyomi , Ohshima Chikako , Ucche Sisca , Lyu Fulian , Hamana Hiroshi , Tahara Hideaki , Kishi Hiroyuki , Hayakawa Yoshihiro 
Published: June 2021

AbstractFor successful immunotherapy for cancer, it is important to understand the immunological status of tumor antigen‐specific CD8+ T cells in the tumor microenvironment during tumor progression. In this study, we monitored the behavior of B16OVA‐Luc cells in mice immunized with a model tumor antigen ovalbumin (OVA). Using bioluminescence imaging, we identified the time series of OVA‐specific CD8+ T‐cell responses during tumor progression: initial progression, immune control, and the escape phase. As a result of analyzing the status of tumor antigen‐specific CD8+ cells in those 3 different phases, we found that the expression of NKG2D defines tumor‐reacting effector CD8+ T cells. NKG2D may control the fate and TOX expression of tumor‐reacting CD8+ T cells, considering that NKG2D blockade in OVA‐vaccinated mice delayed the growth of the B16OVA‐Luc2 tumor and increased the presence of tumor‐infiltrating OVA‐specific CD8+ T cells.