bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pediatric Sciatic Neuropathy Secondary to Subacute Ischial Osteomyelitis: A Case Report
Authors: Cuérel Céline , Habre C. , Steiger Christina N. , DeMarco Giacomo , Tabard-Fougère Anne , Merlini Laura , Sahyoun Cyril , Dayer Romain O. , Ceroni Dimitri 
Published: November 2021

AbstractSciatic neuropathy (SN) is rarely encountered in the pediatric population. The causes of this mononeuropathy are either infectious, immune mediated, toxic, or infiltrative (tumoral). In this article, we presented the case of a 7.5-year-old male child who presented to the emergency department with a painful right lower limb. Magnetic resonance imaging confirmed the diagnosis of subacute osteomyelitis of the ischium, which extended toward the external hip rotators and infiltrated the tissues around the sciatic nerve. Treatment with intravenous antibiotics (flucloxacillin 50 mg/kg/d and gentamicin 10 mg/kg/d) rapidly improved the child's condition and relieved neurological symptoms within a few days. Traumatic and iatrogenic injuries are the most common causes for SN. To our knowledge, this presented case is the first to describe SN due to an infectious process following subacute osteomyelitis.
Comparison of Noninvasive Oscillometric and Intra-Arterial Blood Pressure Measurements in Children Admitted to the Pediatric Intensive Care Unit
Authors: Kaur Jaswinder , Bhargava Siddharth , Pooni Puneet Aulakh , Bhat Deepak , Dhooria Gurdeep S. , Arora Kamaldeep , Kakkar Shruti , Gill Karambir 
Published: November 2021

AbstractIntra-arterial blood pressure (IABP) measurement, although considered the gold standard in critically ill children, is associated with certain risks and lacks widespread availability. This study was conducted to determine the differences and agreements between oscillometric non-invasive blood pressure (NIBP) and invasive IABP measurements in children. Inclusion criteria consisted of children (from 1 month to 18 years) admitted to the pediatric intensive care unit (PICU) of a teaching hospital who required arterial catheter insertion for blood pressure (BP) monitoring. The comparison between IABP and NIBP was studied using paired t-test, Bland–Altman analysis, and Pearson's correlation coefficient. In total, 4,447 pairs of simultaneously recorded hourly NIBP and IABP measurements were collected from 65 children. Mean differences between IABP and NIBP were −3.6 ± 12.85, −4.7 ± 9.3, and −3.12 ± 9.30 mm Hg for systolic, diastolic, and mean arterial BP, respectively (p < 0.001), with wide limits of agreement. NIBP significantly overestimated BP (p < 0.001) in all three BP states (hypotensive, normotensive, and hypertensive), except systolic blood pressure (SBP) during hypertension where IABP was significantly higher. The difference in SBP was most pronounced during hypotension. The difference in SBP was significant in children <10 years (p < 0.001), with the maximum difference being in infants. It was insignificant in adolescents (p = 0.28) and underweight children (p = 0.55). NIBP recorded significantly higher BP in all states of BP except SBP in the hypertensive state. SBP measured by NIBP tended to be the most reliable in adolescents and underweight children. NIBP was the most unreliable in infants, obese children, and during hypotension.
Anesthetic Management of Moyamoya Syndrome Secondary to Sickle Cell Anemia
Authors: Bithal Parmod K. , Jan Ravees , Pandey Ved P. , Ahmad Parvaiz 
Published: November 2021

AbstractMoyamoya disease (MMD) is caused by stenosis or occlusion of internal carotid artery in brain, thereby reducing its blood supply. To augment blood flow, brain develops abnormal anastomotic vessels with deranged carbon dioxide reactivity and tendency to bleed. Moyamoya syndrome (MMS) is the name given to MMD when the latter results from secondary to some associated disease. Occurrence of MMS secondary to sickle cell anemia (SCA) presents unique challenges to neuroanesthesiologists. Management of various physiological parameters for cerebral revascularization surgery for MMD under general anesthesia necessitates vigilant and balanced control of various physiological variables, as the manipulation of a particular physiological variable for one pathology may adversely impact the same physiological variable for the associated disease, which will result in poor outcome of the patient. Therefore, optimum outcome of MMS is determined by a watchful balancing of various physiological parameters under anesthesia.
Effect of Sustained Uterine Compression versus Uterine Massage on Blood Loss after Vaginal Delivery: A Randomized Controlled Trial
Authors: Ghulmiyyah Labib M. , El-Husheimi Alaa , Usta Ihab M. , Colon-Aponte Cristina , Ghazeeri Ghina , Hobeika Elie , Mirza Fadi G. , Tamim Hani , Hamadeh Caroline , Nassar Anwar H. 
Published: November 2021

Objective This study aimed to compare the effectiveness of sustained uterine compression versus uterine massage in reducing blood loos after a vaginal delivery.
Study Design This was a prospective randomized trial conducted at the American University of Beirut Medical Center (AUBMC) between October 2015 and October 2017. Inclusion criteria were women with a singleton pregnancy at ≥36 weeks of gestation, with less than three previous deliveries, who were candidates for vaginal delivery. Participants were randomized into two groups, a sustained uterine compression group (group 1) and a uterine massage group (group 2). Incidence of postpartum hemorrhage (blood loss of ≥500 mL) was the primary outcome. We assumed that the incidence of postpartum hemorrhage at our institution is similar to previously published studies. A total of 545 women were required in each arm to detect a reduction from 9.6 to 4.8% in the primary outcome (50% reduction) with a one-sided α of 0.05 and a power of 80%. Factoring in a 10% dropout rate. Secondary outcomes were admission to intensive care unit (ICU), postpartum complications, drop in hemoglobin, duration of hospital stay, maternal pain, use of uterotonics, or of surgical procedure for postpartum hemorrhage.
Results A total of 550 pregnant women were recruited, 273 in group 1 and 277 in group 2. There was no statistically significant difference in baseline characteristics between the two groups. Type of anesthesia, rate of episiotomy, lacerations, and mean birth weight were also equal between the groups. Incidence of the primary outcome was not different between the two groups (group 1: 15.5%, group 2: 15.4%; p = 0.98). There was no statistically significant difference in any of the secondary outcomes between the two groups, including drop in hemoglobin (p = 0.79).
Conclusion There was no difference in blood loss between sustained uterine compression and uterine massage after vaginal delivery.
Key Points
Idiopathic Polyhydramnios and Neonatal Morbidity at Term
Authors: Polnaszek Brock , Liang Brooke , Zhang Fan , Cahill Alison G. , Raghuraman Nandini , Young Omar M. 
Published: November 2021

Objective Idiopathic polyhydramnios is among the most common etiologies of polyhydramnios. However, conflicting evidence exists regarding the relationship between polyhydramnios and neonatal morbidity. We investigated the association between pregnancies with and without idiopathic polyhydramnios and neonatal morbidity at term.
Study Design This is a retrospective cohort study of singleton, term (i.e., ≥370/7 weeks) pregnancies from 2014 to 2018. Pregnancies complicated by fetal anomalies, pregestational diabetes, and multifetal gestation were excluded. Pregnancies complicated by idiopathic polyhydramnios were defined by the deepest vertical pocket (DVP) ≥8 cm or amniotic fluid index (AFI) ≥24 cm after 20 weeks' gestation and were compared with women without polyhydramnios at time of delivery. These groups were matched 1:2 by gestational age within 7 days at delivery and maternal race. The primary outcome was a composite neonatal morbidity (neonatal death, respiratory morbidity, hypoxic–ischemic encephalopathy, therapeutic hypothermia, seizures, and umbilical artery pH < 7.10). Outcomes were compared between pregnancies with and without idiopathic polyhydramnios. Unadjusted and adjusted risk ratios were estimated using multivariable logistic regression.
Results Idiopathic polyhydramnios was diagnosed in 192 pregnancies and were matched to 384 pregnancies without polyhydramnios. After adjustment for obesity, women with pregnancies complicated by idiopathic polyhydramnios had an increased risk of composite neonatal morbidity 21.4 versus 5.5% (adjusted risk ratio [aRR] = 4.0, 95% confidence interval [CI]: 2.3–6.7). Term neonatal respiratory morbidity was the primary driver 20.3 versus 4.2%, (aRR = 4.8, 95% CI: 2.7–8.7) and included higher use of continuous positive airway pressure 19.8 versus 3.4%, p <0.01 and the need for supplemental oxygen at >12 hours of newborn life 6.8 versus 1.8%, p <0.01.
Conclusion Idiopathic polyhydramnios is associated with term neonatal respiratory morbidity at delivery and during the subsequent hours of newborn life, compared with pregnancies without idiopathic polyhydramnios. Further studies are needed to minimize neonatal morbidity at term.
Key Points
Eligibility, Utilization, and Effectiveness of 17-Alpha Hydroxyprogesterone Caproate in a Statewide Population-Based Cohort of Medicaid Enrollees
Authors: Wang Xi , Garcia Stephanie M. , Kellom Katherine S. , Boelig Rupsa C. , Matone Meredith 
Published: November 2021

Objective The primary objective was to estimate the initiation and adherence rates of 17 α-hydroxyprogesterone caproate (17OHPC) among eligible mothers in a statewide population-based cohort of Medicaid enrollees. The secondary objectives were to (1) determine the association of maternal sociodemographic and clinical characteristics with 17OHPC utilization and (2) assess the real-world effectiveness of 17OHPC on recurrent preterm birth prevention and admission to neonatal intensive care unit (NICU).
Study Design This is a retrospective cohort study using a linked, longitudinal administrative dataset of birth certificates and medical assistance claims. Medicaid-enrolled mothers in Pennsylvania were included in this study if they had at least one singleton live birth from 2014 to 2016 following at least one spontaneous preterm birth. Maternal Medicaid claims were used to ascertain the use of 17OHPC from various manufacturers, including compounded formulations. Propensity score matching was used to create a covariate balance between 17OHPC treatment and comparison groups.
Results We identified 4,781 Medicaid-covered 17OHPC-eligible pregnancies from 2014 to 2016 in Pennsylvania, 3.4% of all Medicaid-covered singleton live births. The population-based initiation rate was 28.5% among eligible pregnancies. Among initiators, 50% received ≥16 doses as recommended, while 10% received a single dose only. The severity of previous spontaneous preterm birth was the strongest predictor for the initiation and adherence of 17OHPC. In the matched treatment (n = 1,210) and comparison groups (n = 1,210), we found no evidence of 17OHPC effectiveness. The risks of recurrent preterm birth (relative risk [RR] 1.10, 95% confidence interval [CI] 0.97–1.24) and births admitted to NICU (RR 1.00, 95% CI 0.84–1.18) were similar in treated and comparison mothers.
Conclusion The 17OHPC-eligible population represented 3.4% of singleton live births. Less than one-third of eligible mothers initiated treatment. Among initiators, 50% were treatment adherent. We found no difference in the risk of recurrent preterm birth or admission to NICU between treatment and comparison groups.
Key Points
Postpartum Opioid Use among Military Health System Beneficiaries
Authors: Watters Julie A. , Banaag Amanda , Massengill Jason C. , Koehlmoos Tracey P. , Staat Barton C. 
Published: November 2021

Objective The aim of the study is to evaluate the prevalence and factors associated with opioid prescriptions to postpartum patients among TRICARE beneficiaries receiving care in the civilian health care system versus a military health care facility.
Study Design We evaluated postpartum opioid prescriptions filled at discharge among patients insured by TRICARE Prime/Prime Plus using the Military Health System Data Repository between fiscal years 2010 to 2015. We included women aged 15 to 49 years old and excluded abortive pregnancy outcomes and incomplete datasets. The primary outcome investigated mode of delivery and demographics for those filling an opioid prescription. Secondary outcomes compared prevalence of filled opioid prescription at discharge for postpartum patients within civilian care and military care.
Results Of a total of 508,258 postpartum beneficiaries, those in civilian health care were more likely to fill a discharge opioid prescription compared with those in military health care (OR 3.9, 95% CI 3.8–3.99). Cesarean deliveries occurred less frequently in military care (26%) compared with civilian care (30%), and forceps deliveries occurred more frequently in military care (1.38%) compared with civilian care (0.75%). Women identified as Asian race were least likely to fill an opioid prescription postpartum (OR 0.79, 95% CI 0.75–0.83). Women aged 15 to 19 years had a lower odds of filling an opioid prescription (OR 0.83, 95% CI 0.80–0.86). Women associated with a senior officer rank were less likely to fill an opioid prescription postpartum (OR 0.83, 95% CI 0.73–0.91), while those associated with warrant officer rank were more likely to fill an opioid prescription (OR 1.14, 95% CI 1.06–1.23).
Conclusion Our data indicates that women who received care in civilian facilities were more likely to fill an opioid prescription at discharge when compared with military facilities. Factors such as race and age were associated with opioid prescription at discharge. This study highlights areas for improvement for potential further studies.
Key Points
Niche level investment challenges for European Green Deal financing in Europe: lessons from and for the agri-food climate transition
Authors: Long Thomas B. , Blok Vincent 
Published: November 2021

AbstractGreen New Deal (GND) policies are proposed to tackle the climate emergency. These policies focus on driving climate innovation through unprecedented financial policy levers. However, while the macro-level financing dynamics are clear, the influence of niche level dynamics of sustainable innovation financing remain unexplored within these policy settings. Through the context of the European Green Deal and a focus on the agri-tech start-up sector in the Netherlands, we identify factors likely to reduce the efficacy of these policies from an innovation management perspective—such as project matching issues, socio-ethical factors or the characteristics of agri-food climate innovations. We go on to conceptualise that these challenges represent a range of asymmetries—from classic information asymmetries to less common value and objective asymmetries—between climate innovators and private investors and financers. Many remedies for asymmetries involve costs, likely to further inhibit the efficacy of the European Green Deal and similar policies. A partnering approach is proposed, where the non-financial resources of incumbent actors are harnessed and leveraged to enhance climate innovation performance.
Slow monomer vibrations in formic acid dimer: Stepping up the ladder with FTIR and Raman jet spectroscopy
Authors: Nejad Arman , Meyer Katharina A. E. , Kollipost Franz , Xue Zhifeng , Suhm Martin A. 
Published: November 2021

In an effort to extend the cold gas phase spectroscopic database of the cyclic formic acid dimer (FAD), we present and analyze the jet-cooled vibrational infrared and Raman spectrum of (HCOOH)2 in the monomer fingerprint region between 600 and 1500 cm−1. The present study bridges the gap between the intermolecular dimerization-induced and the carbonyl stretching fundamentals that have already been reexamined using jet-cooled or high-resolution spectroscopy. This completes the characterization of the jet-cooled vibrational (HCOOH)2 spectrum below the complex OH (CH) stretching fundamentals, and we report resonance-induced FAD combination/overtone transitions that will serve as a valuable reference for a theoretical modeling of its vibrational dynamics. As a by-product, several new formic acid trimer fundamentals are identified in the jet spectra and assigned with the help of second-order vibrational perturbation theory (VPT2). The polar formic acid dimer still eludes detection in a supersonic jet, but we are able to estimate an experimental upper-bound of the polar dimer-to-trimer-to-cyclic dimer intensity ratio to about 1:10:100 under typical expansion conditions. Using VPT2 with resonance treatment (VPT2+K), we reinvestigate the notorious ν22 resonance triad. Generally, we find that VPT2, which is, of course, inadequate for modeling the resonance-rich OH stretching spectrum of FAD, is performing very satisfactorily in predicting fundamental and two-quantum state term values for the slower modes below 1500 cm−1. As these modes are the building blocks for the ultrafast energy dissipation in the OH stretching region, the present work opens the door for its quantitative understanding.
Passive coupling of membrane tension and cell volume during active response of cells to osmosis
Authors: Roffay Chloé , Molinard Guillaume , Kim Kyoohyun , Urbanska Marta , Andrade Virginia , Barbarasa Victoria , Nowak Paulina , Mercier Vincent , García-Calvo José , Matile Stefan , Loewith Robbie , Echard Arnaud , Guck Jochen , Lenz Martin , Roux Aurélien 
Published: November 2021

Significance
Tension is the force-opposing stretch of lipid membranes. It controls cell functions involving membranes. Membranes rupture above a tension threshold, causing cell death if tension is not properly buffered. However, how cell membrane tension is quantitatively regulated is unknown because it is difficult to measure. Using a fluorescent membrane tension probe, we explored the coupling between membrane tension and cell volume changes during osmosis. This coupling is described by an equilibrium theory linking tension to folding and unfolding of the membrane. This coupling is nevertheless actively regulated by cell components such as the cytoskeleton, ion transporters, and mTOR pathways. Our results highlight that cell volume regulation and membrane tension homeostasis are independent from the regulation of their coupling.
When two languages are competing
Authors: Fan Damien Chiaming , Collart Aymeric , Chan Shiao-hui 
Published: November 2021

Abstract
Past studies have shown that expert interpreters were better than novices at using contextual cues to anticipate upcoming
information. However, whether such sensitivity to contextual cues can be traced by means of neural signatures is relatively unexplored. The
present study used event-related brain potentials (ERPs) along with a language-switching paradigm – including non-switched (Chinese–Chinese,
L1–L1) and switched (Chinese–English, L1–L2) conditions – to investigate whether interpreters with many years of experience, interpreters
with a few years of experience and post-graduate-level interpreting students differed in the way they process contextually congruent or
incongruent sentence-final target words. The results show that while the manipulations of congruency and switching independently induced a
strong brain response in all three groups, the interaction between the two factors elicited different patterns across groups during
500–700 ms: (1) while a sustained congruency effect was found in the two less-experienced groups for the switched condition, such an effect
was observed in the most experienced group for both switched and non-switched conditions; (2) only the least-experienced group showed a
frontal negativity towards incongruent trials in the switched condition. These 200 ms transient group differences revealed that it might be
possible to trace the development of interpreting ability by examining the ERP components in a language-switching setting.
Differentiating movement styles in professional tennis: A machine learning and hierarchical clustering approach
Authors: Giles Brandon , Peeling Peter , Kovalchik Stephanie , Reid Machar 
Published: November 2021

ABSTRACTPurpose: Recent explorations of tennis‐specific movements have developed contemporary methods for identifying and classifying changes of direction (COD) during match‐play. The aim of this research was to employ these new analysis techniques to objectively explore individual nuance and style factors in the execution of COD movements in professional tennis. Methods: Player tracking data from 62 male and 77 female players at the Australian Open Grand Slam were analysed for COD movements using a model algorithm, with a sample of 150,000 direction changes identified. Hierarchical clustering methods were employed on the time‐motion and degree characteristics of these direction changes to identify groups of different COD performers. Results: Five unique clusters, labelled “Cutters”, “Gear Changers”, “Lateral Changers”, “Balanced Changers” and “Passive Changers” were identified in accordance with their varying speed, acceleration, degree and directionality of change features. Conclusions: Player COD clustering challenge previously held assumptions regarding on‐court movement style, highlighting the complexity and variation in the sport's locomotion demands. In practice, the speed, acceleration, directionality and degree of change characteristics of each COD style can facilitate athlete profiling and the specificity of training interventions.
Highlights
We used machine learning techniques and cluster analysis methodology to explore the time motion characteristics of direction change skill in professional tennis.
We present five unique types of change of direction style in professional tennis players. These include “Cutters”, “Gear Changers”, “Lateral Changers”, “Balanced Changers” & “Passive Changers”. These style classifications were established in accordance with their varying speed, acceleration, degree and directionality of change features.
We show that the application of machine learning techniques to player tracking data can facilitate a more intricate understanding the sport's physical demands, which can be used to inform training programme design.
Analytical model of the modulated photoluminescence in semiconductor materials
Authors: Moron Nicolas , Bérenguier Baptiste , Alvarez José , Kleider Jean-Paul 
Published: November 2021

Abstract
Modulated photoluminescence (MPL) is an optoelectronic characterization technique of semiconductor materials. Going to high frequencies enables one to characterize fast phenomena, and so materials with a short lifetime such as chalcogenides or III–V absorbers. Some typical signatures have already been experimentally observed. However, physical mechanisms and quantitative analyses are not well understood yet. Here, using both an analytical approach and a full numerical modeling, we study how the energy position of a defect level, its electron and hole capture cross sections, its density, influence the frequency dependence of the MPL phase. We show that quantitative information can be extracted. We also study the effect of additional surface recombination, and of non homogeneities created by carrier generation profiles or asymmetric top surface and bottom surface recombination velocities, where diffusion of the carriers plays a role and can be limiting at high frequency. Finally we apply our model to an experimental result to extract defect parameters of the sample. Our analysis highlights the usefulness of MPL and the importance of having a proper modeling of the experiment.