bluuebunny/crossref_metadata_2025_split huggingface dataset:
Creation of a Novel Preoperative Imaging Review Acronym to Aid in Revision Endoscopic Sinus Surgery
Authors: Karadaghy Omar A. , Peterson Andrew M. , Fox Meha , White Jacob , Bhalla Vidur , Beahm David , Villwock Jennifer , Chiu Alexander G. 
Published: October 2021

Objectives(1) Identify anatomic contributions to chronic rhinosinusitis (CRS) necessitating revision endoscopic sinus surgery (RESS). (2) Create a clinical acronym to guide imaging review prior to RESS that addresses pertinent sites of disease and potential sites of surgical morbidity.Data SourcesOvid MEDLINE, Embase and Medline via Embase.com, Web of Science Core Collection, Cochrane Central Register of Controlled Trials (CENTRAL), and Google Scholar.Review MethodsSystematic search was performed using a combination of standardized terms and keywords. Studies were included if they investigated anatomic contributions to persistent CRS requiring RESS or the relationship between anatomic landmarks and surgical morbidity. Identified studies were screened by title/abstract, followed by full‐text review. Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines were strictly followed.ResultsIn total, 599 articles met screening criteria, 89 were eligible for full‐text review, and 27 studies were included in the final review. The identified anatomic sites of interests are broad; the most frequently cited anatomic region was retained anterior ethmoid cells (22/27 studies), followed by posterior ethmoid cells (14/27 studies). Using the consolidated information, a clinical acronym, REVISIONS, was created: Residual uncinate, Ethmoid cells (agger, Haller, supraorbital), Vessels (anterior and posterior ethmoid), Infundibulum, Septal deviation, I (eye) compartment, Onodi cell, Natural os, and Skull base slope and integrity.ConclusionsThe REVISIONS acronym was developed as a tool to distill the unique anatomic contributions of primary endoscopic sinus surgery failure into a format that can be easily incorporated in preoperative radiologic review and surgical planning to optimize outcomes and minimize complications.
Letter to the editor regarding the article “The global distribution of acute unintentional pesticide poisoning: estimations based on a systematic review”
Authors: Dunn S. Eliza , Reed Jennifer E. , Neumann Christoph 
Published: October 2021

AbstractWe read with interest the article entitled “The global distribution of acute unintentional pesticide poisoning: estimations based on a systematic review”. We wholeheartedly agree that it is important to evaluate the extent of this issue. We would like to understand the numbers provided in this article, which appear to overestimate the global burden of pesticide poisonings. We also feel that addressing the benefits of these chemistries is important for a complete evaluation.
Inequality in dental care expenditure in Iranian households: analysis of income quintiles and educational levels
Authors: Najafi Elahe , Amini-Rarani Mostafa , Moeeni Maryam 
Published: October 2021

Abstract
Background
Oral health is a major public health issue which affects the human life. Access to dental care is one of the important factors in maintaining oral health. This study was aimed to investigate inequality in dental care expenditure in Iranian households.

Methods
The present study is a secondary analysis of a national cross-sectional survey. The data collected from the Households Income and Expenditure Survey in 2016 and 2017. The final sample consisted of 54,354 households living in rural and urban regions of all the provinces. Inequalities in household’s dental care expenditure per capita in respect to income quintiles and educational level were measured based on the Gini coefficient and concentration index.

Results
The results showed that about 8% of households had paid for dental care during the month before sampling. The Gini coefficient value was estimated to be 0.97 and 0.96 for dental care expenditure per capita respectively in absolute and relative measure. It indicated a significant inequality in the dental expenditure among the sample households. The values of concentration index were positive and significant for all dental care subcategories in respect to the provincial and national income quintiles as well as the educational level of the head of the household.

Conclusions
Income and educational inequality in the both absolute and relative dental services expenditure of the Iranian households were in favor of higher income groups as well as higher educational level of household heads. Income inequality was higher in total dental care expenditure per capita and all its subcategories than the educational inequalities of dental expenditure. In order to reduce these inequalities, the policymakers need to pay special attention to low-income households, particularly those with low-educated heads.
Anti-tumor effects of rivoceranib against canine melanoma and mammary gland tumour in vitro and in vivo mouse xenograft models
Authors: Li Qiang , Kim You-Seok , An Ju-Hyun , Kwon Jin-Ah , Han Sang-Hyun , Song Woo-Jin , Youn Hwa-Young 
Published: October 2021

Abstract
Background
Rivoceranib, a novel tyrosine kinase inhibitor, exhibits anti-tumour effects by selectively blocking vascular endothelial growth factor receptor-2 (VEGFR2) in cancer cells. Recently, the therapeutic effects of rivoceranib on solid tumours have been elucidated in human patients. However, the anti-tumour effects of rivoceranib against canine cancer remain unclear. Here, we investigated the anti-tumour effects of rivoceranib using in vitro and in vivo mouse xenograft models.

Methods
We performed cell proliferation, cell cycle, and migration assays to determine the effects of rivoceranib on canine solid tumour cell lines in vitro. Furthermore, apoptosis and angiogenesis in tumour tissues were examined using a TUNEL assay and immunohistochemistry methods with an anti-cluster of differentiation-31 antibody, respectively. Additionally, the expression levels of cyclin-D1 and VEGFR2 activity were determined using western blot analysis.

Results
Rivoceranib treatment showed anti-proliferative effects and mediated cell cycle arrest in the canine melanoma cell line (LMeC) and the mammary gland tumour (MGT) cell line (CHMp). In animal experiments, rivoceranib decreased the average volume of LMeC cells compared to that following control treatment, and similar results were observed in CHMp cells. Histologically, rivoceranib induced apoptosis and exerted an anti-angiogenic effect in tumour tissues. It also downregulated the expression of cyclin-D1 and inhibited VEGFR2 activity.

Conclusion
Our results show that rivoceranib inhibits proliferation and migration of tumour cells. These findings support the potential application of rivoceranib as a novel chemotherapeutic strategy for canine melanoma and MGTs.
Acute HIV infection syndrome mimicking COVID-19 vaccination side effects: a case report
Authors: Triebelhorn Julian , Haschka Stefanie , Hesse Felix , Erber Johanna , Weidlich Simon , Lee Marcel , Hoffmann Dieter , Eberle Josef , Spinner Christoph D. 
Published: October 2021

Abstract
Background
Symptoms of primary HIV infection, including fever, rash, and headache, are nonspecific and are often described as flu-like. COVID-19 vaccination side effects, such as fever, which occur in up to 10% of people following COVID-19 vaccination, can make the diagnosis of acute HIV infection even more challenging.

Case presentation
A 26-year-old man presented with fever and headache following COVID-19 vaccination. The symptoms were initially thought to be vaccine side effects. A diagnostic workup was conducted due to persisting fever and headache > 72 h following vaccination, and he was diagnosed with Fiebig stage II acute HIV infection, 3 weeks after having unprotected anal intercourse with another man.

Conclusion
Thorough anamnesis is key to estimating the individual risk of primary HIV infection, in patients presenting with flu-like symptoms. Early diagnosis and initiation of antiretroviral therapy is associated with better prognosis and limits transmission of the disease.
The optimal duration of anti-tuberculous therapy before pericardiectomy in constrictive tuberculous pericarditis
Authors: Fang Likui , Yu Guocan , Ye Bo , Zhong Fangming , Chen Gang 
Published: October 2021

Abstract
Background
It is unclear about the duration of anti-tuberculous therapy before pericardiectomy (DATT) in the patients with constrictive tuberculous pericarditis. This study aims to explore the optimal DATT and its impact on surgical outcomes in these patients.

Methods
We retrospectively enrolled 93 patients with constrictive tuberculous pericarditis undergoing pericardiectomy and divided them into two groups according to the optimal cutoff value of DATT which was determined by the receiver operating characteristic (ROC) curve and Youden Index. Postoperative and survival outcomes were compared between the two groups.

Results
The optimal cutoff value of DATT was 1.05 (months). The enrolled patients were divided into the DATT ≤ 1.05 group and the DATT > 1.05 group, with 24 (25.8%) and 69 (74.2%) cases, respectively. Comparing with the DATT ≤ 1.05 group, the DATT > 1.05 group had shorter postoperative ICU stay (P = 0.023), duration of chest drainage (P = 0.002), postoperative hospital stay (P = 0.001) and lower incidence of postoperative complications (P < 0.001). There were no statistical differences between the two groups in recurrence and survival outcomes.

Conclusions
It would be of potential benefit to enhance recovery after pericardiectomy if DATT lasted for at least 1 month in the patients with constrictive tuberculous pericarditis.
Hyers–Ulam stability of non-autonomous and nonsingular delay difference equations
Authors: Rahmat Gul , Ullah Atta , Rahman Aziz Ur , Sarwar Muhammad , Abdeljawad Thabet , Mukheimer Aiman 
Published: October 2021

AbstractIn this paper, we study the uniqueness and existence of the solution of a non-autonomous and nonsingular delay difference equation using the well-known principle of contraction from fixed point theory. Furthermore, we study the Hyers–Ulam stability of the given system on a bounded discrete interval and then on an unbounded interval. An example is also given at the end to illustrate the theoretical work.
An air-locking port and high-flow nasal cannula in non-intubated uniportal video-assisted thoracic surgery for pneumothorax with pulmonary dysfunction: a case report
Authors: Yamagishi Hiroya , Wakatsuki Yusuke , Tada Toshihiko , Matsukura Tadashi 
Published: October 2021

Abstract
Background
Non-intubated video-assisted thoracic surgery is a therapeutic option for intractable secondary spontaneous pneumothorax in patients who are poor candidates for surgery with endotracheal intubation under general anesthesia. However, intraoperative respiratory management in this surgery is often challenging because of hypoxia caused by surgical pneumothorax.

Case presentation
A 75-year-old man with idiopathic pulmonary fibrosis who had been on home oxygen therapy underwent non-intubated uniportal video-assisted thoracic surgery for intractable spontaneous pneumothorax. During the operation, oxygen was administered using a high-flow nasal cannula at a high flow rate. An air-locking port for single-incision surgery was used to minimize the inflow of air into the pleural cavity. The intrapleural air was continuously suctioned through the chest tube. The air-leak point was easily identified and closed using ligation. Oxygenation was satisfactory throughout the operation.

Conclusions
Non-intubated uniportal video-assisted thoracic surgery for secondary spontaneous pneumothorax with an air-locking port, continuous pleural suction, and high-flow nasal cannula may achieve satisfactory intraoperative oxygenation in patients with respiratory dysfunction. The intrapleural space can be feasible for surgical manipulation without surgical pneumothorax in non-intubated video-assisted thoracic surgery even when supplied with oxygen at a high flow rate using a high-flow nasal cannula.
Factors predicting relapse and treatment discontinuation with paliperidone 3-monthly long-acting injection: A 2-year naturalistic follow-up study
Authors: Clark Ivana , Wallman Phoebe , Cornelius Victoria , Taylor David 
Published: October 2021

AbstractBackgroundPaliperidone 3-monthly (PP3M) long-acting injection has proven efficacy and effectiveness in schizophrenia. Little is known of its effectiveness in other diagnoses.MethodsAll patients starting PP3M were followed up for 2 years. Main outcome measures were relapse and discontinuation from PP3M.Post hocwe examined outcomes in those switched back to one monthly paliperidone (PP1M) long-acting injection.ResultsOverall, 186 patients were followed-up. At the 2-year end point, 110 patients (59%) were still receiving PP3M, and 129 (70%) were receiving some form of paliperidone long-acting injection. Discontinuation from paliperidone long-acting injections (PPLAIs) was more likely with a nonschizophrenia diagnosis (hazard ratio [HR] for continuation 0.429 [95% confidence intervals (CI) – 0.21, 0.87p = 0.018)), and prior clozapine use [in PP3M patients; HR for discontinuation 1.87 [95% CI – 1.05, 3.30p = 0.032]). Relapse occurred in 20 (11%) of those receiving PP3M. Relapse on PP3M and PPLAIs was more likely in nonschizophrenia diagnosis (HR 0.17 for remaining relapse-free [95% CI – 0.06, 0.50;p = 0.001]; HR 0.21 [95% CI – 0.08, 0.58p = 0.002], respectively), polypharmacy in PP3M patients (HR for relapse 7.91 [95% CI – 3.73, 22.9;p < 0.001]) and PPLAI patients (HR for relapse 6.45 [95% CI – 2.49, 16.5;p < 0.001]), and prior clozapine use in PP3M patients (HR for relapse 6.11 [95% CI – 1.82, 20.5;p = 0.003]) and PPLAI patients (HR for relapse 4.52 (95% CI – 1.51, 13.5;p = 0.007).ConclusionsOutcomes with PP3M are excellent in practice, even when used outside its formal license. PP3M was relatively more effective in those with an F20 schizophrenia diagnosis and in those never before considered for or prescribed clozapine.
Computational singular perturbation method for the non-standard FitzHugh-Nagumo system
Authors: Liu Yaru , Liu Shenquan , Kurths Jürgen 
Published: October 2021

Abstract
An effective computational singular perturbation (CSP) method for solving the non-standard FitzHugh-Nagumo system is constructed and evaluated by detailed algebra factorization. Furthermore, our studies illustrate a geometric CSP framework with the layer and reduced problems for the non-standard FitzHugh-Nagumo system. Finally, the first two CSP manifolds and two CSP fast fibers are also presented for the FitzHugh-Nagumo system by one-step and two-step CSP updates in this context. The CSP method can further describe Fenichel manifolds and facilitate a better understanding of the dynamic properties of complex neuron models or circuit neural models.
О ВОЗМОЖНОСТИ ОПТИМИЗАЦИИ НАУЧНОЙ СТУДЕНЧЕСКОЙ РАБОТЫ
Authors: Melnikova Tomara V. , Preobrazhenskiy Andrey P. , Choporova Ekaterina I. 
Published: October 2021

Цель. Статья посвящена актуальной в условиях современных образовательных систем теме студенческой научной работы. Целью исследования является повышение эффективности студенческой научной работы в высшем учебном заведении, которая характеризуется определенной спецификой, связанной с ее интеграцией в учебный процесс.
Метод или методология проведения работы. Основу исследования образуют системные методы: моделирования, оптимизации, информационных технологий. На их базе есть возможности для построения модели, позволяющей формировать научные компетенции современных специалистов. Отдельным образом рассмотрена информационная составляющая – возможности использования в научной работе системы интернет вещей.
Результаты. Результаты работы заключаются в том, что авторы выделяют базовые виды научной деятельности. После этого рассматривается возможность их группирования, что ведет к механизму редукции. Показана оптимизационная модель, позволяющая определять лидирующие виды научной деятельности студентов. Объясняется механизм редукции.
Область применения результатов. Результаты исследования могут быть применены в образовательных системах высших учебных заведений при рассмотрении возможностей повышения эффективности студенческой научной работы в рамках заданного ресурсного обеспечения.
Coordinación motora gruesa en niños de 7 a 12 años mediante la batería KTK
Authors: Vecino Pico Hugo , Argüello Jorge Eliécer , Villamizar Carrillo Luis Ernesto 
Published: October 2021

Esta investigación hizo una caracterización de la coordinación motora gruesa mediante la batería KTK en niños de 7ª 12 años. Usando estadística se realizó, análisis de frecuencia, medidas de tendencia central y pruebas paramétricas para establecer comparaciones entre el cociente motor, el sexo y la edad. El 97.3 % de la población presenta una coordinación por debajo de la normalidad, el 1,5% de los estudiantes se clasificaron con coordinación normal y solamente el 1,1% mostró resultados superiores del estándar. En lo que respecta al sexo, se pudo establecer que los niños presentan mejores resultados que las niñas; en las pruebas de equilibrio desplazándose hacia atrás y saltos laterales no hay diferencias significativas entre niños y niñas, mientras que para salto unipodal y desplazamiento lateral hay diferencias significativas pues los niños tuvieron mejores resultados que las niñas.
Nowa Muzyka i przyjemność w serii utworów audiowizualnych ASMR Neo Hülckera
Authors: Pasiecznik Monika 
Published: October 2021

New Music developed in the twentieth century under the influence of Theodor W. Adorno’s philosophy. Its sense, according to the philosopher, lies in social criticism, which the composer accomplishes through radical artistic innovation, and the distance from the audience’s expectations. The sensual pleasure of sound reception is not included in the concept of New Music, which preferably should not appeal to anybody, as it “took on the shoulders darkness of the world and all its guilt, and sees its only happiness in knowing misery” (Adorno).
In the ASMR series, the German composer Neo Hülcker breaks this paradigm of perception and proposes a radically different interpretationof New Music.ASMR, or Autonomous Sensory Meridian Response, is a sensation of pleasant tingle, caused by subtle acoustic-haptic phenomena, such as amplified murmurs, whispers, touching objects and materials. Millions of people around the world are watching ASMR videos on YouTube that let them relax nicely.In such video compositions as ASMR Tutorial: How to Play “Pression” by Helmut Lachenmann, ASMR Tutorial: How to Play Mark Andreor ASMR Unwrapping the Piano & iv 11a, and Peter Ablinger: weiss/ weisslich 3 – [super soft ASMR] Neo Hülcker investigates the similarityof sound material of illustrative pieces of New Music and ASMR, raising the question of whether New Music can make someone feeltingly. Presenting in the context of ASMR works by Helmut Lachenmann, Mark Andre and Peter Ablinger, Hülcker explores the hiddenpotential contained in the most radical aesthetics of New Music, namely the suppressed carnal pleasure. The article is an attempt to show the ways how Neo Hülcker redefines the concept of New Music, entering in it the sensual experience of sound.
The Moving Plane Method for Doubly Singular Elliptic Equations Involving a First-Order Term
Authors: Esposito Francesco , Sciunzi Berardino 
Published: October 2021

Abstract
In this paper we deal with positive singular solutions to semilinear elliptic problems involving a first-order term and a singular nonlinearity. Exploiting a fine adaptation of the well-known moving plane method of Alexandrov–Serrin and a careful choice of the cutoff functions, we deduce symmetry and monotonicity properties of the solutions.
Improving mechanical and water vapor barrier properties of the parylene C film by UV-curable polyurethane acrylate coating
Authors: Jing Zekun , Guo Yakun , Ren Meng , Zhao Xingtao , Shao Hong , Zhou Yuanlin , Shuai Maobing 
Published: October 2021

Abstract
Parylene C (PC) films have been widely used in many fields, such as metal anti-corrosion, electronic packaging, etc. However, the relatively poor mechanical properties and the deteriorated water barrier performance due to the easy fracture under external stress have restricted their application. It is a relatively simple and good method to maintain the water vapor barrier and enhance the mechanical properties of PC film by covering a flexible coating on its surface. In this work, a new polyurethane acrylate (PUA) coating was prepared and coated on the PC film by ultraviolet curing technology to form the PC/PUA composite film. The results showed that the PUA coatings could improve the water vapor barrier and mechanical properties of the PC film simultaneously. The water vapor transmittance rate was reduced from 1.1791 g·(m−2·day−1) of the original PC film to 0.5636 g·(m−2·day−1) of the PC/PUA composite film. The elongation at break and the impact energy were increased to 48.36% and 41.67%, respectively, which would widen the application of PC films in the fields of flexible electronics or smart wear.
International Conference of Urban Commons
Authors: Elia Mattia 
Published: October 2021

Abstract
The report seeks to outline the issues the lecturers of the International Conference Held at the University of Turin on the 21st and 22nd June 2021 touched upon. The backbone of the Conference was the rise of Urban Commons describing all the different aspects it involves: the urban voids suitable to host urban commons, the participatory models shaping the governance of commoning, the consequences such phenomenon may imply, and the technological and legal infrastructure may flank and support the development of urban commoning. All this explored by referring to concrete case studies and day-to-day experiences.
The coincidence of two rare diseases with opposite metabolic phenotype: a child with congenital hyperinsulinism and Bloom syndrome
Authors: Melikyan Maria , Gubaeva Diliara , Nikitina Irina , Ryzhkova Daria , Mitrofanova Lubov , Yukhacheva Daria , Pershin Dmitry , Shcherbina Anna , Vasilyev Evgeniy , Proshchina Alexandra , Krivova Yuliya , Tiulpakov Anatoly 
Published: October 2021

Abstract

Objectives
Congenital hyperinsulinism (CHI) is a group of rare genetic disorders characterized by insulin overproduction. CHI causes life-threatening hypoglycemia in neonates and infants. Bloom syndrome is a rare autosomal recessive disorder caused by mutations in the BLM gene resulting in genetic instability and an elevated rate of spontaneous sister chromatid exchanges. It leads to insulin resistance, early-onset diabetes, dyslipidemia, growth delay, immune deficiency and cancer predisposition. Recent studies demonstrate that the BLM gene is highly expressed in pancreatic islet cells and its mutations can alter the expression of other genes which are associated with apoptosis control and cell proliferation.

Case presentation
A 5-month-old female patient from consanguineous parents presented with drug-resistant CHI and dysmorphic features. Genetic testing revealed a homozygous mutation in the KCNJ11 gene and an additional homozygous mutation in the BLM gene. While 18F-DOPA PET scan images were consistent with a focal CHI form and intraoperative frozen‐section histopathology was consistent with diffuse CHI form, postoperative histopathological examination revealed features of an atypical form.

Conclusions
In our case, the patient carries two distinct diseases with opposite metabolic phenotypes.
Crystal structure of (E)-N′-(1-(3-chloro-4-fluorophenyl)ethylidene)-4-hydroxy – tetrahydrofuran (2/1), C17H16ClFN2O2.5
Authors: Bao Xiaobo , Tian Chongchong 
Published: October 2021

Abstract
C17H16ClFN2O2.5, monoclinic, P21/n (no. 14), a = 7.4495(6) Å, b = 16.5328(13) Å, c = 12.8519(10) Å, β = 91.329(1)°, V = 1582.4(2) Å3, Z = 4, R

gt
(F) = 0.0508, wR

ref
(F
2) = 0.1461, T = 100(2) K.