bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel high entropy spinel-type aluminate MAl2O4 (M = Zn, Mg, Cu, Co) and its lithiated oxyfluoride and oxychloride derivatives prepared by one-step mechanosynthesis
Authors: Porodko Olena , Fabián Martin , Kolev Hristo , Lisnichuk Maksym , Zukalová Markéta , Vinarčíková Monika , Girman Vladimír , Da Silva Klebson Lucenildo , Šepelák Vladimír 
Published: October 2021

Abstract
For the first time, a spinel-type high entropy oxide (Zn0.25Cu0.25Mg0.25Co0.25)Al2O4 as well as its derivative lithiated high entropy oxyfluoride Li0.5(Zn0.25Cu0.25Mg0.25Co0.25)0.5Al2O3.5F0.5 and oxychloride Li0.5(Zn0.25Cu0.25Mg0.25Co0.25)0.5Al2O3.5Cl0.5 are prepared in the nanostructured state via high-energy co-milling of the simple oxide precursors and the halides (LiF or LiCl) as sources of lithium, fluorine and chlorine. Their nanostructure is investigated by XRD, HR-TEM, EDX and XPS spectroscopy. It is revealed that incorporation of lithium into the structure of spinel oxide together with the anionic substitution has significant effect on its short-range order, size and morphology of crystallites as well as on its oxidation/reduction processes. The charge capacity of the as-prepared nanomaterials tested by cyclic voltammetry is found to be rather poor despite lithiation of the samples in comparison to previously reported spinel-type high entropy oxides. Nevertheless, the present work offers the alternative one-step mechanochemical route to novel classes of high entropy oxides as well as to lithiated oxyfluorides and oxychlorides with the possibility to vary their cationic and anionic elemental composition.
Effects of the COVID-19 pandemic on mental health (anxiety and depression symptoms) in the United States of America
Authors: Baysan Caner , Palanbek-Yavaş Seher , Emel-Önal Ayşe 
Published: October 2021

Introduction: The COVID-19 pandemic has had a significant mental health impact in the United States of America and around the world.
Objective: To assess some of the effects of the COVID-19 pandemic on the mental health of U.S. adult population, as well as the relationship between the average number of new COVID-19 cases and the average frequency of symptoms of anxiety, depression, and anxiety or depression between April 23 and October 26, 2020.
Materials and methods: Retrospective study. Psychosocial and demographic data were obtained from the Household Pulse Survey community-based website. Data about the number of new COVID-19 cases detected in the USA during the study period were taken from the Our World in Data website. The Spearman’s rank correlation coefficient was used to evaluate the strength of the relationships between the average of new COVID-19 cases during the study period and the average frequency of symptoms of anxiety, depression, and anxiety or depression. These correlations were also assessed in a subgroup analysis (sex, age group, education level, and ethnicity).
Results: A total of 1 351 911 U.S. adults completed the survey. The average rates of depression, anxiety, and anxiety or depression symptoms were 25.7±1.6%, 31.9±2.0%, and 36.8±2.0%, respectively. The average number of new COVID-19 cases was positively correlated with the mean frequency of anxiety, depression, and anxiety or depression symptoms (r=0.858, r=0.710, and r=0.887; p<0.001). Likewise, positive correlations between the average number of new cases and the mean frequency of anxiety or depressive symptoms were found in the subgroups (r=0.484-0.917).
Conclusions: According to our findings, the number of new COVID-19 cases detected during the study period in the USA was positively correlated with the frequency of anxiety or depression symptoms in the participants, that is, as the number of new cases increased, so did the frequency of the symptoms associated with these mental disorders.
Heat Flow in the Cretaceous of Northwestern Kansas and Implications for Regional Hydrology
Authors: Forster Andrea , Merriam Daniel F. 
Published: October 2021

Temperature logs are interpreted to investigate the thermal structure of the units overlying the Kansas portion of the Cretaceous Dakota aquifer. The aim of this study is to determine if additional heat input by fluids exists and thus clarify whether the overall conductive heat flow from the basement through the sequence might be overprinted by heat advection. Although interval thermal gradients are determined for different lithologic (stratigraphic) units, the shale thermal gradients are preferred for heat-flow estimation. Shale thermal conductivity as measured in Mesozoic shales in Nebraska and South Dakota is extrapolated to the area because of the similar lithology. A few thermal-conductivity values are determined in sandstone samples of the Dakota Formation and also used in heat-flow estimation. In general, the noncalcareous, marine Cretaceous shales (Pierre, Carlile, Graneros, and Kiowa) show different thermal gradients. Gradients in the Pierre (average value 58.5°C/km) and Carlile (55.5°C/km) are slightly higher than the average gradient in the Graneros Shale (45.1°C/km) and Kiowa Formation (46.5°C/km). The higher thermal gradients are limited to the extreme northwestern corner of the study area where the Pierre and Carlile are present. The heat-flow density of 69-74 mW/m2 observed there is slightly higher than the average of 60 mW/m2 typical for central and eastern Kansas. The higher heat flow observed is in the range of data reported and mapped for northeastern Colorado and the Nebraska Panhandle on the western flank of the Chadron Arch, an area with geothermal overprint by warm fluids. Regional differences in heat flow in western Kansas seemingly are caused by the different composition, porosity, and permeability of the aquifer and the nearness to recharge areas.
Conditions and Opportunities for Overcoming the Economic Crisis
Authors: Komkov N. I. 
Published: October 2021

Purpose: the purpose of the presented article is to study the conditions and possibilities of overcoming the protracted economic crisis in Russia.Methods: the study is based on the use of a modified information logic model, which establishes the relationships between the identified bottlenecks, the causes of their occurrence and possible ways to eliminate these causes.Results: the possibilities of overcoming the crisis are, first of all, to use the potential accumulated in the Russian economy, dispersed by sectors of the complete technological reproduction cycle, including the extraction of resources, their processing into useful materials and semi-finished products, the production of machinery and equipment, as well as the production of final products, the provision of services, infrastructure and waste disposal. Simultaneously with the search for opportunities for economic growth, it is necessary to draw the attention of the Russian Government and the legislative and executive heads to the necessity to correct the strategic mistakes. They were conducted in the process of choosing a resource-export development strategy, separating the financial sector from the support and interests of the development of domestic industrial production sector, ignoring the potential and opportunities for the development of the domestic scientific and technological complex, using imperfect economic management mechanisms, etc. The work justifies the need to overcome a long economic crisis via the management of new opportunities breakthrough, which involves the harmonious development of all economic sectors based on supporting a domestic scientific and technical complex capable to ensure the high technologies development and the competitive products production.Conclusions and Relevance: substantiating and choosing ways to overcome the economic crisis should be focused on achieving harmonious development of all sectors of the economy and using in management practices at the national, corporate and company levels, such methods and instruments of targeted projects and programs management, which are the core basis for economy and society development strategies.
Measuring the Sciences Contribution to Socioeconomic Development: Russian Approaches in the Global Space of Ideas
Authors: Yanik A. A. 
Published: October 2021

Purpose: this review aims to present the ‘state-of-the-art’ on the theory and practice of measuring the contribution of sciences to socioeconomic progress and trace the Russian approaches in the global space of ideas.Methods: for studying a multidisciplinary sample of academic publications and gray literature includes multifactor systematization, critical analysis, and synthetic generalization in a large context («helicopter view»).Results: a brief history of the subject is presented in the context of the state's use of science for socio-economic development. The review outlines the focus areas of scientific thought, the conceptual frameworks state, current approaches to measuring the contribution of sciences, the limitations and risks of the evaluation practice.Conclusions and Relevance: key areas of scientific thought in the subject under review for 100 years: (1) development of econometric approaches for measuring the «profitability» of science; (2) attempts to identify and measure the societal impacts of science; (3) scientific support of government experiments to use the evaluation technologies for increasing the return of budget investment to science; (4) conceptualizing and universalizing the terms. There are no indisputable solutions in any of these areas. Disappointment with the catch-all indicators and universal metrics encourages the development of case-oriented methods and process-oriented approaches.Russian research covers the full range of issues, but their world recognition (except some achievements of Soviet time) is low. The lack of institutional memory leads to the rediscovery of the ideas of the 20th century. Establishing the equivalence of terms and conceptual approaches used by scientists from different countries and periods will help to effectively use the scientific heritage, avoid duplicate research, provide a fair place to the Russian achievements in world science.
Dual-Class System of Capital Company Formation in the BRICS Countries
Authors: Voskanian R. O. 
Published: October 2021

Purpose: this paper determinates the current level of penetration of the dual-class system of capital company formation in the BRICS group.Methods: are based on the use of methods of analysis, systematization, generalization. A comparative and synthesis methods have been also used to identify trends and patterns in the introduction of multi-voting shares in the BRICS group.Results: the dual-class system of capital company formation in Russia is practically not studied. The article reveals that in Brazil and Russia, despite the discussion of the possibility of distributing multi-voting shares, the legislation does not imply the possibility of using the dual-class system. This issue has not yet been discussed in South Africa.It has been identified that the main reason for the legislative permission for using multi-voting shares is the need to develop companies in the high-tech sector. Another reason is the massive listing of foreign high-tech companies on American stock exchanges, due to the possibility of using the dual-class system. This predetermined the introduction of amendments to the legislation of India and China, according to which companies in the high-tech sector that have not yet passed an IPO can use differential voting rights.It has been receiving that the Indian market is the only one where shares with differentiated voting rights are placed on the stock exchange. At the moment, three companies that passed the IPO before the amendments to the legislation use differentiated voting rights, but not upwards, but on the contrary – downwards: “four shares – three votes”. This characteristic determines the trading of such stocks at a discount.Conclusions and Relevance: harmonization of opportunities for the use of financial instruments in the BRICS market can strengthen the economic potential of states. Allowing the usage of multi-voting shares improves the business environment for high-tech companies and reduces the need for company founders to look for IPO opportunities in jurisdictions where a dual-class capital formation system is allowed.
The Concept of Sustainable Mobility in Modern Megacities
Authors: Zavyalov D. V. 
Published: October 2021

Purpose: to formulate the general conception of sustainable mobility management in modern cities based on an analysis of the main approaches to the management of the development of sustainable mobility.Methods: the study is based on the application of systems analysis methods. The analysis is based on open sources information such as scientific articles, legal and regulatory acts, official strategic planning documents, analytical and methodical materials of Russian and international conferences. The article also includes the results of the author's empirical research conducted.Results: an analysis of the development of sustainable transport mobility in large cities and current strategies for its further formation was carried out. It allowed identifying the main elements of the conceptual model of the development of transport mobility. The research defines the structure of an adaptive system for sustainable mobility management, which would form a basis for developing a sustainable mobility concept to effectively organize various stakeholders' cooperation.Conclusions and Relevance: local solutions for transportation mobility may not be practical or can lead to a conflict of interests. That calls for the complex approach to forming sustainable mobility as a feature of a city transportation system to satisfy the demand for mobility to increase the quality of life in the cities. The conceptual basis for the development of sustainable mobility consists of goal setting, planning, collaboration, implementation, usage.The effective management of sustainable mobility can be achieved by implementing digital analytical platforms, working as a single ecosystem. Developing such an ecosystem can be time-consuming and directly influenced by technological, infrastructural, legal, and economic factors. The most urgent is to redesign the existing mobility patterns to achieve the environmental goals, the higher quality of life of city residents, the engagement of different stakeholders in sustainable mobility development.
Business development & feasibility study of small-scale powdered coffee agroindustry
Authors: Kesuma Indra , Rusdan  , Machrus M. , Thahir Andi 
Published: October 2021

Purpose of Study: This study aims to analyze the level of visibility of low-scale ground coffee agro-industry and determine the role of the government in the development of low-scale ground coffee agro-industry.
Methodology: This research was conducted using a low-scale survey agro-industry method which was applied to a ground coffee centre in one of the provinces in Indonesia. The number of samples is seven low-scale coffee business units. Data analysis used is financial analysis (NPV, IRR, Net B/C ratio, and Payback Period), Break-Even Point analysis, and sensitivity analysis.
Results: The results showed that the low-scale ground coffee agro-industry was profitable and looked to be continued (IRR 99%, NPV 27,883,981.46 to 16,076,282,505.24 and Net B/C of 1.02 to 1.32), the sensitivity analysis showed that the cost of production to the scale of costs decreased, namely the decline in production below 20%.
Application: The creativity of producers in the marketing of processed coffee products and innovation of flavour variants is important for consumer attractiveness in maintaining the stability of agro-industry income.
Novelty: As for the role of the government, the seven production units have received guidance, counselling, and training.
The impact of Location-based Marketing strategies on retail sectors in Al Batinah region during COVID 19 Pandemic
Authors: Shekhar Shantanu , Chandrasekaran Kumaresan , Mathew Joshy 
Published: October 2021

Purpose: Location-based marketing has become an essential component in today’s businesses. The principal objective of this study is to investigate the growing significance of using location-based marketing services to small and medium-scale marketers and customers.
Methodology: This is an exploratory study, which aims to explore the impact of location-based marketing on the retail sector of the Al Batinah region in the Sultanate of Oman.
Main Findings: Social media platforms play an important role in the Location-Based marketing of various retail sectors such as SME’s and these platforms play a major role in helping retailers to make decisions whether they wish to market their products by using this platform or not.
Implications: All organizations’ top-level management must focus on data mining to identify the right customers and at the same time they should focus on innovative marketing strategies on LBS.
Novelty: This study provides motivations and insights that drives businesses and customers to use these LBM services.
LncRNA CRNDE Promoted Colorectal Cancer Cells Reisitance To Paclitaxel Through Wnt/β-Catenin Signaling Pathway
Authors: Ma Rui , Yu Chuan-yang , Tao Xiang , Yang Zhi , Huang Qi , You Pei-dong , Tian Jin-hai , Cao Jia , Cao Jie , Wang Li-bin 
Published: October 2021

Abstract
Background

The lncRNA colorectal neoplasia differentially expressed (lncRNA CRNDE) is commonly over-expressed in different human cancers and involved in different biological functions. Paclitaxel(PTX) is a tricyclic diterpenoid compound which often used as a natural anticancer drugs in cancer treatments. Although there have many research reports about the mechanisms of LncRNA involved in PTX treatment, there are no any research about lncRNA CRNDE and PTX resistance in colorectal cancer. The purpose of this study is to investigate the mechanisims of LncRNA CRNDE involving PTX resistance in colorectal cancer.
Results

We constructed lncRNA CRNDE over-expression vector and transfected it into SW620 cell. CCK8, Transwell experiments proved that over-expression of lnc CRNDE increased SW620 cells proliferation and invasion, while the si-CRNDE group was significantly decreased. over-expression CRNDE can significantly up-regulate β-catenin, c-myc, APC and Axin2 expression and affect the expression of cyclinD1 and CDK4 after treated with PTX.
Conclusion

lncRNA CRNDE promotes CRCs proliferation, invasion and migration. Over-expression of LncRNA CRNDE enhanced the reisitance of CRC to PTX through inhibition of Wnt/ β-catenin signaling pathway.
Medical Students Perceptions Over Their Motivations and Competencies to Volunteer in COVID-19 Pandemic - An Opportunity to Develop Leadership Skills During Medical Training
Authors: Siqueira Marina Alves Martins , Torsani Matheus Belloni , Gameiro Gustavo Rosa , Chinelatto Lucas Albuquerque , Mikahil Bruna Chacon , Tempski Patricia Zen , Martins Milton A. 
Published: October 2021

Abstract
BackgroundConsidering evidence on competency-based curriculum and the benefits of volunteering, this study highlights new ideas to improve medical education during the COVID-19 pandemic. We investigated the motivations and perceptions on competencies developed as leadership and management skills in medical students who joined COVID-19 Volunteering Program in a brazilian medical school.MethodsWe performed a cross-sectional, quantitative and qualitative study involving medical students from the University of Sao Paulo (USP)/Brazil. They were invited to participate in an institutional Volunteering Program during the pandemic, and filled online application forms, including sociodemographic fields and two open-ended questions about motivation to volunteer and perceptions on their own competencies. At the end of the Program, students who were involved in management-related activities were also invited to participate in focus group interviews to track their perceptions about volunteering in this area. Data were submitted to descriptive and content analysis methods. All participants provided informed consent through electronic signature.Results286 medical students have subscribed to the Volunteering Program: 171 (60%) were men, 152 (53%) were enrolled in 5th year and 158 (55%) were 23-25 years old. One-hundred and twelve (44%) students volunteered motivated by altruistic reasons, 95 (37%) reported duty and 47 (19%) prioritized academic interests. Concerning CanMEDS competencies, 91 (36%) students’ responses matched with the Scholar component, followed by 51 (20%) with Collaborator, 49 (20%) with Professional, 32 (13%) with Communicator, 17 (7%) with Leader and 11 (4%) with Health Advocate. In focus groups, students reported the importance of management and leadership skills as a curricular component, motivations to volunteer, the acquired skills from volunteering in management and leadership-related activities, highlighting the development of resilient attitude.ConclusionsStudents who participated in the FMUSP Volunteering Program reported being motivated to help others (altruistic reasons) and to serve society as future health professionals (duty). Knowledge and work-related competencies prevailed over leadership or soft skills, emphasizing the importance of including such activities in curriculum. Participating in management-related activities could help develop a more resilient attitude towards medical training.Take home messagesVolunteering programs offer students opportunities to develop essential competencies for the future health professional. Thus, we should think about including such activities in curricular structure.
Efficacy of Modified Thoracoabdominal Nerves Block Through Perichondrial Approach in Open Gynecological Surgery: A Prospective Observational Study and a Cadaveric Evaluation
Authors: TANAKA Nobuhiro , SUZUKA Takanori , KADOYA Yuma , OKAMOTO Naoko , SATO Mariko , KAWANISHI Hideaki , AZUMA Cho , NISHI Mayumi , KAWAGUCHI Masahiko 
Published: October 2021

Abstract
BACKGROUNDː Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) was first described as a peripheral nerve block by Tulgar in 2019. This technique provides an analgesic effective range from Th7–11 with a single puncture per side. Although the efficacy and effective duration of M-TAPA have been reported, further examination is required. Therefore, this study aimed to evaluate the analgesic range and effective duration of M-TAPA in open gynecologic surgery.METHODSː Following approval, 10 adult female patients scheduled for open radical hysterectomy via a vertical incision or laparotomy using a midline incision from under the xiphoid process to the symphysis pubis were enrolled. The primary outcome was the number of anesthetized dermatomes at 2 and 24 h postoperatively. Secondary outcomes included numerical rating scale scores and the total amount of fentanyl used. Cadaveric evaluation was performed to assess the spread of the dye. RESULTSː The median numbers (interquartile range) of anesthetized dermatomes at 2 and 24 h postoperatively were 6 (5–7) and 6.5 (5–7) in the anterior cutaneous branch area and 5 (4–7) and 7 (5–7) in the lateral cutaneous branch area, respectively. There was an 85% chance of simultaneously acquiring analgesia in areas innervated by Th8–Th11, including complete block in areas innervated by the anterior cutaneous branches of Th9–10. Cadaveric evaluation showed the spread of the dye in Th8–11.CONCLUSIONSːM-TAPA may have analgesic effects in the areas supplied by the anterior cutaneous branches of Th8–11.TRAIL REGISTRATION:IRB approval (No.2700; registered on July 10, 2020) and registration (UMIN Clinical Trials Registry: UMIN000041137; registered on July 17, 2020)