bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of isolated left ventricular noncompaction using cardiac magnetic resonance tissue tracking in global, regional and layer-specific strains
Authors: Zhang Jiamin , Jiang Mengchun , Zheng Chao , Liu Hui , Guo Yangyu , Xie Xingzhi , Zou ZhiMin , Zhou Xiaoyue , Xia Liming , Luo Meichen , Zeng Mu 
Published: March 2021

AbstractWe used cardiac magnetic resonance tissue tracking (CMR-TT) to quantitatively analyze the global, regional and layer-specific strain of isolated left ventricular noncompaction (ILVNC). Combined with late gadolinium enhancement (LGE), we initially explored the effect of focal myocardial fibrosis on myocardial strain. CMR was performed in 63 patients with ILVNC and 52 patients without ILVNC (i.e., the control group). The ILVNC group was divided into an LGE(+) group (29 patients) and an LGE(−) group (34 patients) according to the presence or absence of late gadalinum enhancement (LGE). CVI42 software was used to measure global and regional (basal, middle, apical) radial strain (RS), circumferential strain (CS), longitudinal strain (LS), subendocardial LS and subepicardial LS. The basal–apical strain gradient was defined as the apical mean strain minus the basal mean strain. We then compared differences between these strain parameters. The subendocardial-subepicardial LS gradient was defined as the maximum subendocardial LS minus the subepicardial LS. Compared with the control group, the global and regional RS, CS, LS and the subendocardial, subepicardial LS of the ILVNC group were significantly diminished (P < 0.01). Compared with the LGE(−) group, the global and regional RS, CS, LS and the subendocardial, subepicardial LS of the LGE(+) group were significantly diminished (P < 0.05). In the ILVNC group, the basal–apical CS and LS gradient, and the subendocardial-subepicardial LS gradient were significantly lower than those in the control group (P < 0.01). There were significant differences in myocardial strain between patients with and without ILVNC. ILVNC revealed a specific pattern in terms of strain change. The myocardial strain of the cardiac apex and endocardium was significantly lower than that of the cardiac base and epicardium, respectively. Myocardial strain reduction was more significant in ILVNC patients with focal myocardial fibrosis.
Synchronous facial action binds dynamic facial features
Authors: Johnston Alan , Brown Ben B. , Elson Ryan 
Published: March 2021

AbstractWe asked how dynamic facial features are perceptually grouped. To address this question, we varied the timing of mouth movements relative to eyebrow movements, while measuring the detectability of a small temporal misalignment between a pair of oscillating eyebrows—an eyebrow wave. We found eyebrow wave detection performance was worse for synchronous movements of the eyebrows and mouth. Subsequently, we found this effect was specific to stimuli presented to the right visual field, implicating the involvement of left lateralised visual speech areas. Adaptation has been used as a tool in low-level vision to establish the presence of separable visual channels. Adaptation to moving eyebrows and mouths with various relative timings reduced eyebrow wave detection but only when the adapting mouth and eyebrows moved asynchronously. Inverting the face led to a greater reduction in detection after adaptation particularly for asynchronous facial motion at test. We conclude that synchronous motion binds dynamic facial features whereas asynchronous motion releases them, allowing adaptation to impair eyebrow wave detection.
Higher exercise tolerance early after allogeneic hematopoietic stem cell transplantation is the predictive marker for higher probability of later social reintegration
Authors: Hamada Ryota , Arai Yasuyuki , Kondo Tadakazu , Harada Kazuhiro , Murao Masanobu , Miyasaka Junsuke , Yoshida Michiko , Yonezawa Honami , Nankaku Manabu , Ouchi Sayako , Kitakubo Wakako , Wadayama Tomoko , Kanda Junya , Takaori-Kondo Akifumi , Ikeguchi Ryosuke , Matsuda Shuichi 
Published: March 2021

AbstractAs the proportion of long-term survivors after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is on the rise, it is essential to consider the significance of quality of life (QOL), including reintegration with society (returning to school or work). This retrospective cohort study aims to illustrate the precise epidemiology of social reintegration later after allo-HSCT and determine its predictive indicators. We enrolled 56 patients, and 40 patients (71%) attained social reintegration at 2 years post-HSCT. Reintegration failure markedly correlated with an inferior performance status and concurrent chronic graft-versus-host disease. In non-reintegrated patients, the physical function at discharge measured by the 6-min walking distance (6MWD) was markedly decreased. On the multivariate risk analyses, sex (female; odds ratio (OR) 0.07; 95% confidence interval (CI) 0.01–0.54; p = 0.01), HCT-CI (≥ 2; OR 0.10; 95% CI 0.01–0.84; p = 0.03), and change in 6MWD (per 5% increase; OR 1.47; 95% CI 1.01–2.13; p = 0.04) were significant predictors of later social reintegration. This study suggests that a multidisciplinary strategy including rehabilitation is essential, especially in patients with poor predictive markers at an early phase, and we should consider suitable rehabilitation programs to prevent a decline in exercise tolerance and improve social reintegration and overall QOL in patients after allo-HSCT.
Low HDL and high triglycerides predict COVID-19 severity
Authors: Masana Lluís , Correig Eudald , Ibarretxe Daiana , Anoro Eva , Arroyo Juan Antonio , Jericó Carlos , Guerrero Carolina , Miret Marcel·la , Näf Silvia , Pardo Anna , Perea Verónica , Pérez-Bernalte Rosa , Plana Núria , Ramírez-Montesinos Rafael , Royuela Meritxell , Soler Cristina , Urquizu-Padilla Maria , Zamora Alberto , Pedro-Botet Juan ,   the STACOV-XULA research group, Rodríguez-Borjabad Cèlia , Andreychuk Natalia , Malo Ana , Matas Laia , del Señor Cortes-Fernandez Maria , Mauri Marta , Borrallo Rosa M. , Pedragosa Àngels , Gil-Lluís Pilar , Lacal-Martínez Ana , Barragan-Galló Patricia , Vives-Masdeu Glòria , Arto-Fernández Carmen , Boutrouki Omar El , Vázquez-Escobales Andrea , Antón-Alonso Maria Cristina , Rivero-Santana Sergio , Gómez Albert , García Sara , Rial-Lorenzo Núria , Ruiz-Ortega Lourdes , Alonso-Gisbert Oriol , Méndez-Martínez Ana Inés , Iglesias-López Hada , Climent Elisenda , Güerri Roberto , Soldado Jade , Fanlo Marta , Taboada Alicia , Gutierrez Liliana 
Published: March 2021

AbstractLipids are indispensable in the SARS-CoV-2 infection process. The clinical significance of plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to ascertain the association of the plasma lipid profile with SARS-CoV-2 infection clinical evolution. Observational cross-sectional study including 1411 hospitalized patients with COVID-19 and an available standard lipid profile prior (n: 1305) or during hospitalization (n: 297). The usefulness of serum total, LDL, non-HDL and HDL cholesterol to predict the COVID-19 prognosis (severe vs mild) was analysed. Patients with severe COVID-19 evolution had lower HDL cholesterol and higher triglyceride levels before the infection. The lipid profile measured during hospitalization also showed that a severe outcome was associated with lower HDL cholesterol levels and higher triglycerides. HDL cholesterol and triglyceride concentrations were correlated with ferritin and D-dimer levels but not with CRP levels. The presence of atherogenic dyslipidaemia during the infection was strongly and independently associated with a worse COVID-19 infection prognosis. The low HDL cholesterol and high triglyceride concentrations measured before or during hospitalization are strong predictors of a severe course of the disease. The lipid profile should be considered as a sensitive marker of inflammation and should be measured in patients with COVID-19.
Efficient joint resource allocation for cognitive internet of vehicles networks based on asymmetric relay transmission
Authors: Song Xiaoqin , Wang Kuiyu , Xu Lei , Tan Yazhu , Miao Juanjuan 
Published: March 2021

AbstractIn the internet of vehicles (IoV) networks, a direct connection from the source end to the destination end may not be established due to the fast vehicle speed, long distance between vehicles, variable vehicle density, serious channel fading etc. In this paper, a joint resource allocation (RA) in the relay‐aided IoV networks is modelled as a mixed binary integer non‐linear programming (MBINP), which maximises the throughput of cognitive IoV networks among different subcarriers and relays. To further reduce the computational complexity, a suboptimal scheme is presented. First, the appropriate relay and subcarrier pairs are obtained by averaging the power allocation among the cognitive sources and relays. Second, an alternative optimisation mechanism is proposed to the power allocation. Simulation results show that, different from the symmetric time‐slot relay transmission, the asymmetric one can significantly increase the degree of freedom for transmission. Therefore, it is more robust to the impact of the relay node location on the throughput. Moreover, the proposed suboptimal RA algorithm not only can obtain the system capacity close to the optimal one, but also can reduce the computational complexity. At the same time, unacceptable degradation caused by severe channel fading is avoided.
Improve conditional adversarial domain adaptation using self‐training
Authors: Wang Zi , Sun Xiaoliang , Su Ang , Wang Gang , Li Yang , Yu Qifeng 
Published: March 2021

AbstractDomain adaptation for image classification is one of the most fundamental transfer learning tasks and a promising solution to overcome the annotation burden. Existing deep adversarial domain adaptation approaches imply minimax optimization algorithms, matching the global features across domains. However, the information conveyed in unlabelled target samples is not fully exploited. Here, adversarial learning and self‐training are unified in an objective function, where the neural network parameters and the pseudo‐labels of target samples are jointly optimized. The model's predictions on unlabelled samples are leveraged to pseudo‐label target samples. The training procedure consists of two alternating steps. The first one is to train the network, while the second is to generate pseudo‐labels, and the loop continues. The proposed method achieves mean accuracy improvements of 2% on Office‐31, 0.7% on ImageCLEF‐DA, 1.8% on Office‐Home, and 1.2% on Digits than the baseline, which is superior to most state‐of‐the‐art approaches.
Investigation of water droplet‐initiated discharges on laser textured silicone nano‐micro composites using UHF and fluorescent fibre techniques
Authors: Amizhtan Somasundaram Karthikeyan , Ganesh Parvathy , Srinivasan Balaji , Vasa Nilesh J. , Aravindan Sivanandam , Sarathi Ramanujam 
Published: March 2021

AbstractLaser texturing has been carried out on the surface of the silicone nano‐micro composites to achieve super hydrophobic properties, and water droplet‐initiated Corona discharge studies were carried out. The Corona inception voltage (CIV) exhibits considerable enhancement with increase in the nano filler content under DC voltage compared with AC voltage. The corona inception voltage is high with the textured surface and is found to have direct correlation with contact angle of the composite specimen. The Corona inception voltage was measured using Ultra‐high frequency (UHF) and fluorescent fibre techniques. It is observed that the fluorescent fibre technique is more sensitive in identifying discharges. Frequency domain analysis of UHF signal shows a dominant frequency at 1 GHz and for fluorescent signal, the spectral content is in the range of DC to 10 MHz. The rise time and pulse width of the UHF signal increases with the increase in the nano filler in composite material. The energy content of UHF/fluorescent signal due to discharges shows similar trend with its increase in energy with variation in its magnitude of the signal formed. The pulse width of fluorescent signal formed due to water droplet‐initiated discharges under AC and DC voltage is almost the same, and with the textured specimen it is quite low than the non‐textured material.
Automatic heart disease class detection using convolutional neural network architecture‐based various optimizers‐networks
Authors: Fradi Marwa , Khriji Lazhar , Machhout Mohsen , Hossen Abdulnasir 
Published: March 2021

AbstractEarly heart disease class detection is of great interest to reduce the mortality rate. In this context, computational techniques have been proposed to solve this issue. Thus, here, a deep learning architecture is proposed to automatically classify the patient’s Electrocardiogram (ECG) signal into a specific class according to the ANSI–AAMI standards. The proposed methodology is a multi‐stage technique. The first stage combines an R–R peak extraction with a low‐pass filter applied on the ECG data for noise removal. The second stage shows the proposed convolutional neural network‐based fully connected layers architecture, using different network optimizers. Different ECG databases, including challenging tasks, have been used for validation purpose. The whole system is implemented on both CPU and GPU for complexity analysis. For the predicted improved PTB data set, the classification accuracy results achieve 99.37%, 99.15% and 99.31% for training, validation and testing, respectively. Besides, for the MIT‐BIH‐database, the training, validation and testing accuracies are 99.5%, 99.06% and 99.34%, respectively. A top F1‐score of 0.99 is obtained. Experimental results show a high achievement compared to the state‐of‐the‐art models where the implementation of GPU confirms the low computational complexity of the system.
Strukturelle Implementierung eines Fast-Track-Programms – wie geht das?
Authors: Schwenk Wolfgang , Lang Ina , Huhn Marion 
Published: March 2021

ZusammenfassungFast-Track- oder ERAS-Konzepte gehen mit klinisch relevanten Vorteilen für operierte Patienten und ökonomischen Vorteilen für das Krankenhaus einher. Dennoch sind Fast-Track-Konzepte in Deutschland bislang nur in einzelnen chirurgischen Kliniken realisiert worden. Weder das Fehlen wissenschaftlicher Evidenz noch Einschränkungen durch das G-DRG-System sind Grund dieser ausbleibenden Fast-Track-Verbreitung in Deutschland. Vielmehr ist der Wandlungsprozess von der traditionellen perioperativen Behandlung zur evidenzbasierten Fast-Track-Therapie komplex und erfordert einen strukturierten und aufwendigen Implementierungsvorgang. International sind Programme zur Etablierung des Fast-Track etabliert und in zahlreichen Kliniken erfolgreich durchgeführt worden. Diese strukturierte Fast-Track-Implementierung wird in die Abschnitte organisatorische Vorbereitung, klinische Implementierung und Ergebnisüberprüfung gegliedert. Aufgrund der großen Komplexität der Wandlung ist eine
externe Begleitung und Schulung des multiprofessionellen Teams durch externe Fast-Track-Spezialisten sinnvoll.
Femoral Neck Stress Fracture of a Male, Healthy Marathon Runner – Case Report and Literature Review
Authors: Weinrich Luise , Dahne Michael , Lindner Tobias , Stöckle Ulrich , Tsitsilonis Serafeim 
Published: March 2021

AbstractIn the present report, a case of a healthy, 38–year-old male recreational marathon runner who presented in the emergency department is discussed. He was diagnosed with a stress fracture of the femoral neck and treated surgically using a dynamic hip screw (DHS). One year after surgery, the patient was able to return to most of his previous sports activities. In the present report, the existing literature on the subject is exhibited and the points of interest in terms of incidence, risk factors, diagnosis, classification, treatment, and long-term outcome are analyzed. We suggest operative treatment of stress fractures of the femoral neck even in cases of complete undisplaced ones. This way, the risk of a displacement is counteracted, and patients can quickly return to daily activities without having to withstand long-term immobilization.
Reine Männersache?! – geschlechtsspezifische Perspektiven in der Arbeit mit suchtkranken Männern
Authors: Wirtz Markus 
Published: March 2021

ZusammenfassungMänner stellen den überwiegenden Teil aller Klienten in
Einrichtungen der Suchthilfe in Deutschland. Männerspezifische
Angebote, die Suchterkrankungen im Kontext männlicher Sozialisation
und tradierter Rollenbilder betrachten, sind demgegenüber noch immer
die Ausnahme. Seit mehr als 20 Jahren widmet sich die
LWL-Koordinationsstelle Sucht bereits dem Thema
„Männlichkeiten und Sucht“ – und hat in
dieser Zeit konkrete Methoden und Materialien für die
männerspezifische Arbeit mit suchtkranken Männern
entwickelt.
Clean One-Pot Multicomponent Synthesis of Pyrans Using a Green and Magnetically Recyclable Heterogeneous Nanocatalyst
Authors: Maleki Ali , Ghassemi Mina 
Published: March 2021

AbstractCopper ferrite (CuFe2O4) magnetic nanoparticles (MNPs) were synthesized via thermal decomposition and applied as a reusable and green catalyst in the synthesis of functionalized 4H-pyran derivatives using malononitrile, an aromatic aldehyde, and a β-ketoester in ethanol at room temperature. The nanoparticles were characterized by FT-IR, EDX, SEM, TGA, and DTG analysis. The catalyst was recovered from the reaction mixture by applying an external magnet and decanting the mixture. Recycled catalyst was reused for several times without significant loss in its activity. Running the one-pot three-component reaction at room temperature, using a green solvent under environmentally friendly reaction conditions, ease of catalyst recovery and recyclability, no need for column chromatography and good to excellent yields are advantages of this protocol.
Auditive and Vestibular Changes Related to the Use of Hydroxychlorochine and Chlorochine: An Integrative Review
Authors: Britto Diana Babini Lapa de Albuquerque , Rocha Mônyka Ferreira Borges , Silva Jéssica Dayane da , Pinheiro Natália dos Santos , Silva Lidiane Kelvin da , Advíncula Karina Paes 
Published: March 2021

Abstract
Introduction The use of hydroxychloroquine and chloroquine is formally indicated in cases of chronic autoimmune diseases. However, the use of these medications has already been associated with possible transitory or definitive alterations in hearing function and/or vestibular function in humans, when administrated in the short and long terms.
Objective To describe, through a literature analysis, the functional vestibular and/or hearing alterations, caused by the use of hydroxychloroquine and chloroquine in youths and adults.
Data Synthesis In total, 2,481 studies were identified in the initial search: out of these 32 were selected for a full-text reading, and 9 were selected after the exclusion of those which did not meet the eligibility criteria. Of these, four articles pointed to the presence of vestibular and auditory-associated alterations, three indicated only auditory pathologies, and two, vestibular disorders. Regarding the auditory alterations, tinnitus was the most frequent symptom, and bilateral sensorineural hearing loss was described in most studies, varying in degree from mild to severe. As for the vestibular alterations, vertigo was the most reported symptom.
Conclusion Knowledge of the auditory and vestibular effects after the use of these substances can help in the decision regarding the best treatment, enabling the consideration of other available therapies for patients at risk of suffering those alterations, reducing the risk of auditory and vestibular disorders.
Mundulla yellows (Mundulla Yellows dieback).
Authors:   Australia, CRCNPB
Published: March 2021

Abstract

Invasiveness is not a term that one associates with abiotic stresses. Whilst early studies pointed towards a pathogen-induced decline, more recent studies have concluded that the cause of Mundulla yellows is abiotic in nature. This new lethal plant-dieback syndrome was first detected in South Australia in the 1970s (Cotton, 1998). Similar symptoms have since been observed in eucalypts in Spain, Peru and Syria (Randles et al., 2010) and potentially the USA (I Smith, University of Melbourne, Australia, personal communication cited in Czerniakowski et al., 2008). Surveys of remnant eucalypts in South Australia revealed an increase in MY of 30% between 1994 and 1999 (Paton and Cutten, 2000). In some areas of the Limestone Coast of South Australia, more than 70% of eucalypts have been affected and at least 87 species and 29 genera were documented as expressing MY-like symptoms in South Australia (Mundulla Yellows Task Group, 2004; Hanold et al., 2006).
Pregnancy-associated risk factors and incidence of systemic sclerosis in primiparous women: A nationwide population-based cohort study
Authors: Lee Kyung-Ann , Kim JongSun , Choi Wonho , Kim Hyun-Sook , Seo Gi Hyeon 
Published: March 2021

AbstractObjectivesTo evaluate the pregnancy-related risk factors and incidence rate (IR) of systemic sclerosis (SSc) in primipara using the Health Insurance Review and Assessment database, covering all medical claims in South Korea.MethodsFrom the database, 2,260,952 primipara aged 18–49 years from 2008 to 2018 were identified. The patients were followed up after their index delivery until December 2019. A Cox proportional hazard analysis was performed to identify the association of pregnancy-related factors with SSc development.ResultsThe SSc IR was 0.62 cases per 100,000 patient-years. Primipara had a higher risk of developing SSc after 3 years postpartum than in the first 3 years of delivery (OR = 1.98, 95% CI: 1.36–2.78, p &lt; .001). A multivariate analysis showed that older age (35–49 years) (HR = 2.14, 95% CI: 1.05–4.35, p = .037) and a Caesarean section (CS) (HR = 1.86, 95% CI: 1.10–3.15, p = .021) are risk factors for SSc. At 3 years postpartum, CS (HR = 2.97, 95% CI: 1.39–6.32, p = .005) and a female infant (HR = 2.28, 95% CI: 1.11–4.71, p = .026) were associated with SSc development.ConclusionHaving a CS, late childbirth, and a female infant are the risk factors for SSc in primipara. This study establishes the IR of SSc in primipara.
Development of the concept of managing stakeholders in the Russian educational agglomeration based on the Agile methodology
Authors: Ivanova O E , Uvarina N V , Lysenko Yu V , Pakhtusova N A , Savchenkov A V 
Published: March 2021

Abstract
The paper substantiates the relevance of developing the concept of managing stakeholders in the educational agglomeration based on the flexible methodology in an unstable environment. The aim of the paper is to conceptualize the management of stakeholders of educational agglomeration based on the Agile methodology. The main research methods were dialectical method, critical analysis method, descriptive statistics methods, communicative and pragmatic approach, stakeholder approach, and conceptualization. The concept of managing stakeholders in the Russian educational agglomeration based on the Agile methodology was developed. This conceptualization implements the empirically-based and design-based orientation of the flexible methodology and takes into account the practical benefits of stakeholder effects from participation in the educational agglomeration. The main elements of the stakeholder management system are: the person, object and subject of management, management principles, management cycle and management of the terms of cooperation. The conclusion about managing the stakeholders of the educational agglomeration based on the Agile methodology is substantiated.