bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of the impact of ice gouging on the Arctic marine pipeline systems
Authors: Силина Ирина Георгиевна , Иванов Вадим Андреевич , Знаменщиков Сергей Валерьевич 
Published: August 2021

Для исследования методик оценки влияния ледовой экзарации на подводные трубопроводы проанализирована отечественная и зарубежная нормативно-техническая база в области проектирования, строительства и эксплуатации морских трубопроводных систем, подробно рассмотрены общие подходы к решению данного вопроса. Систематизирован опыт строительства и эксплуатации трубопроводов в условиях замерзающих акваторий, представлены способы их защиты от повреждений в результате дрейфа ледовых образований. Дана оценка характера формирования и особенностей распределения ледово-экзарационных форм по глубине акваторий. Показано, что существующая методология оценки воздействия ледовой экзарации на морские трубопроводы не позволяет в полной мере учесть льдогрунтовое взаимодействие. Установлена целесообразность разработки критериев для определения минимальной безопасной глубины заложения подводных трубопроводов в районах с дрейфующими льдами. Обозначены направления дальнейших исследований механизмов ледового выпахивания, деформаций прилежащего к трубе грунтового массива и поведения заглубленного трубопровода. Полученные результаты позволят дополнить существующую методологию учета воздействия ледовой экзарации на морские трубопроводы, прокладываемые в замерзающих акваториях, с целью обеспечения их безопасности и надежности.
To consider the methods of assessing the impact of ice gouging phenomenon on subsea oil and gas pipelines, the authors analyzed Russian and foreign codes and standards in the field of offshore pipeline systems design, construction and operation, and also considered in detail scientific approaches to investigate this issue. Within the framework of the analysis of peculiarities of offshore pipelines operation in areas with ice gouging, systematization of experience gained from pipeline systems operation in freezing waters was carried out, and methods of pipeline protection from damages caused by drifting ice formations were considered. The assessment of ice induced gouges formation and distribution features is performed. It is shown that the assessment methods presented in current codes and standards to determine the ice gouging impact on marine pipelines do not allow to directly take into account the ice-soil interaction. The feasibility of developing criteria for determining the minimum required burial depth for subsea pipelines in areas with ice gouging is determined. The directions of further research to ensure safe and failure-free operation of subsea pipeline systems in freezing water areas are presented.
Analisis Kemampuan Pemecahan Masalah Matematis Peserta Didik Ditinjau dari Resiliensi Matematis dan Gender
Authors: Nurfitri Rizqy Ayu , Jusra Hella 
Published: August 2021

Kemampuan pemecahan masalah matematis adalah sebuah kebutuhan yang wajib dimiliki oleh peserta didik namun faktanya kemampuan yang dimiliki termasuk kategori rendah karena muncul sikap negatif pada pelajaran matematika yang disebabkan oleh kesulitan dan hambatan yang dialami. Menganalisis dan mendeskripikan kemampuan pemecahan masalah matematis peserta didik ditinjau dari resiliensi matematis dan gender merupakan tujuan dari penelitian. Pemilihan subjek dengan teknik purposive sampling dengan 6 subjek penelitian kelas VII yang memenuhi kriteria. Penelitian kualitatif melalui pendekatan deskriptif adalah jenis penelitian yang digunakan dengan menggunakan instrumen non tes angket resiliensi matematis, tes kemampuan pemecahan masalah matematis, dan wawancara. Kriteria dalam menentukan keenam subjek berdasarkan resiliensi matematis yang tergolong tinggi, sedang, dan rendah masing-masing kategori terdapat dua orang yang terdiri dari perempuan dan laki-laki. Penelitian ini menggunkan analisis data model Miles dan Huberman dengan hasil kedua subjek resiliensi tinggi tidak mudah menyerah saat mengalami kesulitan dan mampu memenuhi keempat indikator pemecahan masalah namun perempuan lebih baik dari laki-laki, sedangkan subjek yang memiliki resiliensi sedang hanya mampu memenuhi tiga indikator pemecahan masalah dimana subjek kurang mampu memenuhi indikator melaksanakan rencana karena kurang teliti dalam menyelesaikan masalah, namun subjek laki-laki lebih baik dari perempuan dan kedua subjek cenderung tidak menyerah saat mengalami kesulitan. Kedua subjek yang memiliki resiliensi rendah mudah menyerah saat mengalami kesulitan dan belum mampu memenuhi keempat indikator, namun perempuan lebih baik dari laki-laki.
Late Leaf Spot Defoliation, Microclimate Modification, and Southern Stem Rot Development in Peanut (Arachis hypogaea L.) in South Carolina
Authors: Munir M. , Kirk K. R. , Plumblee M. T. , Anco D. J. 
Published: August 2021

ABSTRACT
Southern stem rot (SSR) of peanut, caused by Athelia rolfsii, is commonly influenced by environmental conditions. Defoliation from late leaf spot (LLS), caused by Nothopassalora personata, alters canopy structure and has the potential to affect microclimates. A better understanding of the potential interaction between SSR and LLS through potential microclimate modification might contribute to improved disease management. Eight field experiments were conducted from 2016 to 2019 to investigate the effect of LLS defoliation on peanut canopy and soil microclimates and SSR development. To encourage different levels of LLS defoliation, 3 spray programs (3, 4 and 6 chlorothalonil applications) were applied across four cultivars varying in susceptibility to LLS and SSR via a split-plot design. Defoliation was rated every 2 weeks from 75 days after planting (DAP) to harvest. Canopy and soil temperature and soil moisture were recorded from 75 to 140 DAP. Interaction of LLS spray program and peanut cultivar significantly affected LLS defoliation in nearly all trial years except in 2019 where low disease pressure occurred due to dry weather. Significant relationships were observed between LLS defoliation and daily maximum canopy temperatures and between area under LLS defoliation curve (AUDC) and slope of daily canopy temperature change. The influence of LLS defoliation on the microclimate was generally erratic. The relationship between AUDC and SSR was not significant. Results from this study suggest that the influence of LLS on microclimate was insufficient to substantially affect SSR development.
TEKNIK PENGGUNAAN PUPUK METODE TEMPEL MISEL ORGANIK-ANORGANIK PADA TANAMAN KACANG HIJAU (Vigna radiata L.) DENGAN PENGUJIAN BERBAGAI DOSIS DI ZONA AKAR
Authors: Agustamar Agustamar 
Published: August 2021

Penggunaan pupuk yang tepat gunan dan efisien memerlukan teknik sederhana yaitu metode tempel misel organik-anorganik dengan proses inkubasi. Metode ini sudah terbukti pada praktek penanaman padi metode SRI (the Sistem of Rice Intensification) pada sawah bukaan baru. Pembuktian untuk tanaman kacang hijau sangat diperlukan sebagai karakter tanaman berumur pendek pada jenis leguminosa. Fungsi tanaman kacang hijau tidak dapat diragukan apalagi pada kondisi pandemic Covid-19 saat ini, karena ada kandungan asam amino Lysine yang mampu meningkatkan daya tahan tubuh dari serangan virus. Metode tempel misel organik-anorganik berasal dari hasil kompos dalam hal ini kompos asal feses sapi melalui inkubasi 21 hari. Pembuatan 1 t.ha-1 pupuk diperlukan 80% kompos, 20% tanah lempung berliat, dan berturut-turut Urea, SP-36 dan KCl sebanyak 15, 12.5, dan 7.5 kg. Perlakuan dosis pupuk di zona akar berturut-turut 0, 1, 2, 3 dan 4 t.ha-1 dengan pengulangan sebanyak 4 kali dalam media tanam polibag 6 kg tanah Ultisol. Pengujian dapat memberikan informasi bahwa (1) berbagai dosis pupuk metode tempel organik-anorganik mampu meningkatkan pertumbuhan dan komponen hasil tanaman kacang hijau, (2) penggunaan dosis pupuk 2 t.ha-1 menunjukkan hasil terbaik terhadap pertumbuhan tanaman, komponen hasil dan hasil biji kacang hjau, dan (3) penggunaan dosis pupuk metode tempel organik-anorganik berlebihan sebesar 3-4 t.ha-1 cenderung melambatkan waktu berbunga termasuk penundaan waktu panen, meningkatkan tinggi tanaman dan bahkan menurunkan hasil biji. Karena pengujian ini pada skala pot terbatas, maka disarankan untuk penerapannya di lapangan pada luasan tertentu (125 m2)
ASSESMENT KESIAPAN KADER POSYANDU DALAM PELATIHAN PENGGUNAAN MEDIA ONLINE
Authors: Masitha Arsyati Asri , Krisna Chandra Vindi 
Published: August 2021

Posyandu (Pos Pelayanan Terpadu) merupakan bentuk pemberdayaan masyarakat yang bertujuan untuk meningkatkan kesehatan kesehatan ibu dan anak pada level dasar oleh kader. Tujuan utamanya adalah memberikan kemudahan masyarakat dalam akses pelayanan kesehatan bagi ibu, bayi dan anak balita. Pada masa pandemi pelayanan posyandu menjadi kurang optimal. Dibutuhkan keterampilan kader dengan memanfaatkan media online agar dapat mmeberikan pelayanan psoyandu pada masyarakat. Tujuan penelitian ini adalah untuk mengetahui kesiapan seluruh kader Posyandu di RW 5 Kelurahan Cibadak, Kecamatan Tanah Sareal, Kota Bogor dengan menggunakan media online. Metode penelitian yang digunakan adalah kuantitatif, dengan design korelasional.
KEJADIAN SARIAWAN PADA PEROKOK AKTIF DAN PASIF BERBASIS DATA IFLS 5 (Recurrent Aphthous Stomatitis among Active and Passive Smoker from Indonesian Family Life Survey 5)
Authors: Kusuma Aerosta Danny , Januar Sitorus Rico , Flora Rostika 
Published: August 2021

<p class="16bIsiAbstrak">Sariawan tercatat sebagai penyakit yang dikeluhkan seperlima populasi dunia. Dan beberapa studi mengungkapkan tidak adanya pengaruh antara kebiasaan merokok dengan kejadian sariawan. Namun penelitan sebelumnya memiliki jumlah sampel yang tidak besar. Penelitian ini bertujuan untuk menguraikan prevalensi dan distribusi sariawan dengan kebiasaan merokok pada perokok aktif dan pasif. Metode penelitian yang dipergunakan adalah cross-sectional dengan mempergunakan data <em>Indonesia Family Life Survey</em> (IFLS) 5 sebagai data induk untuk menganalisis hubungan antara kebiasaan merokok dan kejadian sariawan. Prevalensi sariawan didapatkan dari keterangan lisan partisipan terhadap keluhan sariawan dalam sebulan terakhir. Kebiasaan merokok adalah kategori paparan rokok antara perokok aktif dan pasif. Distribusi paparan didasarkan atas usia, jenis kelamin, pendidikan, gejala depresi, riwayat hipertensi dan diabetes, dan jenis makanan yang dikonsumsi dalam sepekan terakhir. Peluang kejadian dari faktor pajanan dominan dihitung dengan analisis multivariat regresi logistik. Hasil dari penelitian ini mengungkapkan angka kejadian sariawan sebesar 17,89%. Dan hasil analisis bivariat menunjukkan adanya hubungan antara kebiasaan merokok dengan kejadian sariawan. Peluang kejadian sariawan dari faktor resiko dominan, antara lain kebiasaan merokok, usia, gejala depresi, riwayat diabetes melitus, konsumsi mie instan, minuman berkarbonasi, makanan pedas dan gorengan sebesar 55,40%. Dari penelitian tersebut didapatkan kesimpulan terdapat hubungan antara kebiasaan merokok dengan kejadian sariawan dengan<em> pvalue&gt;0,0001.</em></p>
The Predictive Value of N-Terminal Probrain Natriuretic Peptide for Infection in Patients With Acute Myocardial Infarction
Authors: Dai YiNing , Wan XiaoLiang , Liu Can , Duan ChongYang , Shao Shuai , Chen HongHuan , Wang Litao , Lin JiJin , Xue Ling , Chen JiYan , He PengCheng , Liu YuanHui , Tan Ning 
Published: August 2021

Background: Infections increase the risk of poor outcomes in patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI). However, predicting patients at a high risk of developing infection remains unclear. Moreover, the value of N-terminal probrain natriuretic peptide (NT-proBNP) for predicting infection is still unknown. Thus, we aimed to assess the relationship between NT-proBNP and the following development of infection, and clinical adverse outcomes in patients with STEMI undergoing PCI.Methods: STEMI patients undergoing PCI were consecutively enrolled from January 2010 to July 2016 and divided into groups according to baseline NT-proBNP levels: tertiles T1 (&lt;988 pg/mL), T2 (988–3520 pg/mL), and T3 (≥3520 pg/mL). The primary endpoint was infection during hospitalization.Results: A total of 182 (27%) patients developed in-hospital infection. The incidence of infection increased from T1 to T3 (10.5, 17.7, and 54.5%, P &lt; 0.001). NT-proBNP was an independent risk factor (adjusted odds ratio = 1.39, 95% confidence interval (CI) = 1.12–1.73, P = 0.003) and presented accurately predicting infection (area under curve = 0.774). Multivariate cox analysis showed that NT-proBNP was a significant risk factor for major adverse clinical events (MACE) at follow-up (adjusted HR = 1.92, 95% CI = 1.61–2.29, P &lt; 0.001).Conclusion: The baseline NT-proBNP level has a good predictive value for infection and MACE in STEMI patients undergoing PCI.
Formation of Bubble-Loop Complexes During Helium Radiation in Fe-9Cr Steel
Authors: Shi Tiantian , Liu Wenbo , Su Zhengxiong , Yan Xu , Lu Chenyang , Yang Zhaoxi , He Xinfu , Yan Wei , Yun Di 
Published: August 2021

In the present study, the Fe-9Cr model alloy was irradiated with 240 keV He2+ at 550°C with a dose of 0.5 dpa at the peak damage region. The depth distribution of bubbles in Fe-9Cr alloy was investigated by transmission electron microscopy (TEM). The experimental results revealed that the spatial distribution of bubbles along the depth is different. In the region with higher helium concentration and irradiation dose, the bubbles inclined to be situated inside the plane of loops, forming a structure of “bubble-loop complex.” However, in regions where the helium concentration and irradiation dose are relatively low, the number of “bubble-loop complexes” significantly decreased. In addition, the Burgers vector of “bubble-loop complexes” was identified as &lt;100&gt; type. Radiation-induced enrichment of Cr atoms at the “bubble-loop complexes” was also quantitatively estimated by energy-dispersive X-ray spectroscopy (EDS) in the scanning TEM mode.
Transcription Factors of CAT1, EFG1, and BCR1 Are Effective in Persister Cells of Candida albicans-Associated HIV-Positive and Chemotherapy Patients
Authors: Aboualigalehdari Elham , Tahmasebi Birgani Maryam , Fatahinia Mahnaz , Hosseinzadeh Mehran 
Published: August 2021

BackgroundBiofilm is an accumulation of cells, which are formed on mucosal surfaces of the host as well as on medical devices. The inherent resistance of Candida strains producing biofilms to antimicrobial agents is an important and key feature for biofilm growth, which can lead to treatment failure. This resistance is due to the regulatory increase of the output pumps, the presence of extracellular matrix, and the existence of persister cells. Persister cells are phenotypic variants that have MICs similar to antibiotic-sensitive populations and are able to tolerate high doses of antibiotics. The current study investigated the possible role of EFG1, BCR1, and CAT1 in the establishment or maintenance of persister cells in Candida albicans strains that produce biofilms.MethodsAfter identifying Candida isolates by molecular methods, C. albicans isolates were confirmed by sequencing. Isolation of persister cells and determination of their MIC were performed by microdilution method. Then, RNA extraction and cDNA synthesis were performed from 60 C. albicans isolates under promoting and inducing conditions. Afterward, the mean expression of BCR1, EFG1, and CAT1 genes in both persister and non-persister groups was calculated using real-time qPCR. Phylogeny tree of persister and non-persister group isolates was drawn using ITS fragment.ResultsA total of 77 persister isolates were taken from the oral cavity of HIV patients as well as from patients undergoing chemotherapy. Biofilm intensity in persister isolates separated from HIV-infected patients was different from the non-persister group. The mean fold change of BCR1 (10.73), CAT1 (15.34), and EFG1 (2.41) genes in persister isolates was significantly higher than these genes in isolates without persister.ConclusionIt can be concluded that the most important factor in the production of persister cells is biofilm binding and production, not biofilm development or mature biofilm production, which was found in the expression of BCR1 gene without change in the expression of EFG1 gene in the persister group. Also, catalase plays an essential role in the production of persister in C. albicans biofilm producers with ROS detoxification.
The Effect of MicroRNA-126 Mimic Administration on Vascular Perfusion Recovery in an Animal Model of Hind Limb Ischemia
Authors: Theofilis Panagiotis , Vogiatzi Georgia , Oikonomou Evangelos , Gazouli Maria , Siasos Gerasimos , Katifelis Hector , Perrea Despoina , Vavuranakis Manolis , Iliopoulos Dimitrios C , Tsioufis Costas , Tousoulis Dimitris 
Published: August 2021

Background: MicroRNAs have been linked to angiogenesis and could prove to be valuable future therapeutic targets in ischemic cardiovascular diseases.Methods: Ten-week-old male C57Bl/6 mice were subjected to left femoral artery ligation and were treated with microRNA-126 mimic at a dose of 5 mg/kg (Group A, n = 10) or 5 mg/kg microRNA mimic negative control (Group B, n = 10) on days 1, 3, and 7. Laser Doppler imaging was performed to verify successful ligation on day 0 and to evaluate differences in the ischemic-to-normal (I/N) hind limb perfusion ratio on day 28. Muscle tissue expression of microRNA-126 and vascular endothelial growth factor (VEGF) was determined via PCR.Results: Following microRNA-126 mimic administration in Group A subjects, we noted a stepwise increase in I/N hind limb perfusion ratio (Day 0: 0.364 ± 0.032 vs. Day 8: 0.788 ± 0.049 vs. Day 28: 0.750 ± 0.039, p = 0.001). In Group B a stepwise increase in I/N hind limb perfusion ratio was observed (Day 0: 0.272 ± 0.057 vs. Day 8: 0.382 ± 0.020 vs. Day 28: 0.542 ± 0.028, p = 0.074). Muscle tissue expression of microRNA-126 in the ischemic hind limb of Group A was 350-fold lower compared to the ischemic hind limb of Group B (p &lt; 0.001). A higher expression (14.2-fold) of VEGF in the ischemic hind limb of microRNA-126-treated mice compared to that of control group was detected (p &lt; 0.001). A statistically significant negative correlation was noted between microRNA-126 and VEGF tissue expression levels in the ischemic limbs of the entire study population.Conclusion: MicroRNA-126 delivery in the ischemic hind limb of mice improved vascular perfusion with VEGF upregulation.
Magnetic Resonance Image of Neonatal Acute Bilirubin Encephalopathy: A Diffusion Kurtosis Imaging Study
Authors: Zheng Hongyi , Lin Jiefen , Lin Qihuan , Zheng Wenbin 
Published: August 2021

Background and Objective: The abnormal T1-weighted imaging of MRI can be used to characterize neonatal acute bilirubin encephalopathy (ABE) in newborns, but has limited use in evaluating the severity and prognosis of ABE. This study aims to assess the value of diffusion kurtosis imaging (DKI) in detecting ABE and understanding its pathogenesis.Method: Seventy-six newborns with hyperbilirubinemia were grouped into three groups (mild group, moderate group, and severe group) based on serum bilirubin levels. All the patients underwent conventional MRI and DKI serial, as well as 40 healthy full-term infants (control group). The regions of interest (ROIs) were the bilateral globus pallidus, dorsal thalamus, frontal lobe, auditory radiation, superior temporal gyrus, substantia nigra, hippocampus, putamen, and inferior olivary nucleus. The values of mean diffusivity (MD), axial kurtosis (AK), radial kurtosis (RK), and mean kurtosis (MK), and fractional anisotropy (FA), radial diffusivity (RD), and axis diffusivity (AD) of the ROIs were evaluated. All newborns were followed up and evaluated using the Denver Development Screening Test (DDST). According to the follow-up results, the patients were divided into the normal group, the suspicious abnormal group, and the abnormal group.Result: Compared with the control group, significant differences were observed with the increased MK of dorsal thalamus, AD of globus pallidus in the moderate group, and increased RD, MK, AK, and RK value of globus pallidus, dorsal thalamus, auditory radiation, superior temporal gyrus, and hippocampus in the severe group. The peak value of total serum bilirubin was moderately correlated with the MK of globus pallidus, dorsal thalamus, and auditory radiation and was positively correlated with the other kurtosis value. Out of 76 patients, 40 finished the DDST, and only 9 patients showed an abnormality. Compared with the normal group, the AK value of inferior olivary nucleus showed significant differences (p &lt; 0.05) in the suspicious abnormal group, and the MK of globus pallidus, temporal gyrus, and auditory radiation; RK of globus pallidus, dorsal thalamus, and auditory radiation; and MD of globus pallidus showed significant differences (p &lt; 0.05) in the abnormal group.Conclusion: DKI can reflect the subtle structural changes of neonatal ABE, and MK is a sensitive indicator to indicate the severity of brain damage.
Individual-, Family-, and School-Level Ecological Correlates With Physical Fitness Among Chinese School-Aged Children and Adolescents: A National Cross-Sectional Survey in 2014
Authors: Dong Yanhui , Chen Manman , Chen Li , Wen Bo , Yang Yide , Wang Zhenghe , Ma Yinghua , Song Yi , Ma Jun , Lau Patrick W. C. 
Published: August 2021

Introduction: Few studies have examined the association between the individual-, family-, and school-level ecological correlates and physical fitness among Chinese children and adolescents, which is the purpose of the present study.Methods: A total of 157,168 children and adolescents, 10-18 years of age, with physical fitness data in 2014, participated in the study. Physical fitness was assessed, using six tests: forced vital capacity, standing long jump, sit and reach, body muscle strength, 50-m dash, and endurance running. Scores were aggregated to form a summary physical fitness indicator (PFI), which was then classified into five levels: low, low-middle, middle, middle-high, and high. Each option of individual-, family-, and school-level measures were constructed into a positive or negative correlate of physical fitness and then accumulated as a composite ecological score.Results: Among the 20 individual-, family-, and school-level correlates, 18 were found to be significantly associated with PFI, with high PFI levels being correlated with the positive group of correlates and low PFI levels correlated with the negative group of correlates (p &lt; 0.05). High scores of ecological correlates were associated with a high level of PFI [adjusted odds ratio (OR) = 1.06, 95% CI: 1.06, 1.07)] whereas low scores were associated with a low level of PFI (OR = 0.95, 95% CI:0.95, 0.95). The ecological correlates at the individual, school- and family-levels were shown to be significantly related to high PFI among Chinese children and adolescents aged 10-18 years with different ORs of 5.97 (95% CI: 5.51, 6.47), 3.94 (3.66, 4.24), and 1.25 (1.19, 1.31). The PAR% of 20 cumulative factors effects due to the negative and positive responses for low PFI levels were 35.9 and 16.1%, and, for high PFI levels, were 15.3 and 24.1%, among Chinese children and adolescents, respectively. Compared with the correlates at family and school levels, the correlates at individual levels had the largest PAR%.Conclusion: Individual-, family-, and school-multilevel factors had a significant cumulative association with either improving or worsening aspects of physical fitness. Individual level factors remain at the core of physical fitness improvement. Comprehensive policies and measures are urgently needed to enhance the physical fitness of Chinese children and adolescents through involving further individual and environmental factors.