bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Calcination Temperature on Physical properties of Ni0.6Zn0.4Fe2O4 Ferrite nanoparticles
Authors: pendyala sivakumar , Yadav G.k.Sivasankara 
Published: February 2021

Abstract
The influence of Calcination temperature on the physical properties of Ni0.6Zn0.4Fe2O4 ferrite nanoparticles were investigated. These ferrite nanoparticles have been synthesized by sol-gel auto combustion method using citric acid as fuel agent at different calcination temperatures (4000C, 5000C and 6000C). The Morphological investigation, average crystallite size and microstructure of the material were examined by using X-ray diffraction (XRD) and confirmed by field emission scanning electron microscope (FESEM) and FTIR spectra. The Effects of calcination temperature on the dielectric and magnetic properties were calculated by using LCR meter and vibrating sample magnetometer (VSM). The XRD result shows a single-phase cubic spinel structure with average crystallite size increases from 27 to 29.5 nm, with an increase of temperature. The highest saturation magnetization was found at a calcination temperature 6000C with value 80.39 emu/g, and the value coercive field (Hc) was inverse with the crystallite size.
In vitro conservation and genetic diversity of threatened species of Melocactus (Cactaceae)
Authors: Torres-Silva Gabriela , Schnadelbach Alessandra Selbach , Bezerra Hédina Basile , Lima-Brito Alone , Resende Sheila Votória 
Published: February 2021

Abstract
The high endemism, the natural habitat degradation, and the over-collection for ornamental purposes have led some species such as Melocactus paucispinus and M. glaucescens to be threatened with extinction. The use of in vitro conservation techniques, such as slow growth storage, promotes the preservation of genetic diversity with integrity. The goal of this study was to establish a strategy for in vitro conservation of apical segments of the cladode of M. paucispinus and M. glaucescens and evaluate the genetic diversity of individuals from in vitro germinated plants. For such purpose, different concentrations of the plant regulator ancymidol and the osmotic agent sucrose on the inhibition of the in vitro growth were tested, and the genetic diversity of M. paucispinus and M. glaucescens individuals stored in vitro was evaluated. Sucrose showed higher efficiency in the reduction of growth than ancymidol for both species. However, due to the reduction in survival percentage, the use of sucrose over 75 g L− 1 in the in vitro conservation of both species for 360 days is not recommended. In the genetic diversity analysis, 76.92% of polymorphic loci (P), expected heterozygosity (He) = 0.276 and Shannon index (S) = 0.414 were observed for M. paucispinus. For M. glaucescens, the observed values were P = 95.38%, He = 0.228 and S = 0.369. These values observed here were higher than those previously found for the natural populations of these species, which demonstrated that this in vitro collection showed genetic diversity and can be used in management and reintroduction programs of these species.
Evaluation of a Temperature-Induced Chitosanase Bacterial Cell Surface Display System for the Efficient Production of Chitooligosaccharides
Authors: Li Qianqian , Wang Tuantuan , Ye Yangzhi , Guan Shimin , Cai Baoguo , Zhang Shuo , Rong Shao-feng 
Published: February 2021

Abstract
Objective To establish a temperature-induced chitosanase bacterial cell surface display system to produce chitooligosaccharides (COSs) efficiently for industrial applications. Results Temperature-inducible chitosanase CSN46A bacterial surface display systems containing one or two copies of ice nucleation protein (InaQ-N) as anchoring motifs were successfully constructed on the basis of Escherichia coli and named as InaQ-N-CSN46A and 2InaQ-N-CSN46A. The specific enzyme activity of 2InaQ-N-CSN46A reached 886.33±0.81 U/g cell dry weight, which was 45.6% higher than that of InaQ-N-CSN46A. However, few proteins were detected in 2InaQ-N-CSN46A hydrolysis system. Therefore, 2InaQ-N-CSN46A had higher hydrolysis efficiency and stability than InaQ-N-CSN46A. GPC revealed that under the optimum enzymatic hydrolysis temperature, the final products were mainly chitobiose and chitotriose. Chitopentaose accumulated (77.62%) when the hydrolysis temperature reached 60 ℃. FTIR and NMR analysis demonstrated that the structures of the two hydrolysis products were consistent with those of COSs.Conclusions In this study, chitosanase was expressed on the surfaces of E. coli by increasing induction temperature, and chitosan was hydrolysed directly without enzyme purification steps. This study provided a novel strategy for industrial COSs production.
One Patient Diagnosed With Primary Refractory Diffuse Large B Cell Lymphoma Successfully Salvaged With BCL2 Inhibitor Followed by anti-CD19 CAR-T Suffered From a Secondary Onset of Severely CRS
Authors: Zhang Yuanfeng , Sun Shuxiang , An Licai , Wang Yanming , Chu Xiaoxia , Liu Xiaoqian , Liu Yinghui 
Published: February 2021

Abstract
Background Treatment of relapsed/refractory diffuse large B cell lymphoma (DLBCL) eligible for transplantation is limited by the efficacy of salvage therapy. Chimeric antigen receptor modified T cell (CAR-T) therapy has achieved the highest response rate of salvage therapy for relapsed/refractory aggressive B cell lymphoma. Cytokine release syndrome (CRS) and cytopenia are main side effects of CAR-T therapy. Case presentation A 61 years old Chinese male diagnosed as DLBCL was treated with rituximab combined with chemotherapy, unfortunately, he was resistant to first-line chemotherapy and other regimens. Due to high expression of BCL2 protein and amplification of BCL2 by next sequence generation, BCL2 inhibitor combined with low intensity chemotherapy was given to him as a bridge to anti-19 CAR-T therapy. Although escalation of dose from 100mg per day to 400mg in one week, he had no tumor lysis syndrome and achieved partial response. He suffered persist pancytopenia after CAR T-cells infusion, moreover, a severely secondary CRS on 54th day was observed and responded well to steroid.Discussion and conclusions BCL2 inhibitor may have a role in frontline or salvage therapy of DLBCL, especially for those with high BCL2 protein expression, mechanism of which should be still investigated. CAR-T therapy revolutionized the salvage of primary refractory DLBCL, but we should focus on persist cytopenia and severe CRS, and we reported the latest secondary CRS till now.
Invariant quadratic operator associated with Linear Canonical Transformations
Authors: Ranaivoson Ravo Tokiniaina , Andriambololona Raoelina , Hanitriarivo Rakotoson 
Published: February 2021

Abstract
The main purpose of this work is to identify the general quadratic operator which is invariant under the action of Linear Canonical Transformations (LCTs). LCTs are known in signal processing and optics as the transformations which generalize certain useful integral transforms. In quantum theory, they can be identified as the linear transformations which keep invariant the canonical commutation relations characterizing the coordinates and momenta operators. In this paper, LCTs corresponding to a general pseudo-Euclidian space are considered. Explicit calculations are performed for the monodimensional case to identify the corresponding LCT invariant operator then multidimensional generalizations of the obtained results are deduced. It was noticed that the introduction of a variance-covariance matrix, of coordinate and momenta operators, and a pseudo-orthogonal representation of LCTs facilitate the identification of the invariant quadratic operator. According to the calculations carried out, the LCT invariant operator is a second order polynomial of the coordinates and momenta operators. The coefficients of this polynomial depend on the mean values and the statistical variances-covariances of these coordinates and momenta operators themselves. The eigenstates of the LCT invariant operator are also identified with it and some of the main possible applications of the obtained results are discussed.
Relationship between blood glucose level and preoperative anxiety and postoperative pain in children (5-15 years old) undergoing adenotonsillectomy
Authors: Meybodian Mojtaba , Ansari Mohammad , Dadgarnia Mohammadhossein , Vaziribozorg Sedighe 
Published: February 2021

Abstract
Introduction:

The aim of this study was to determine the relationship between blood glucose level and preoperative anxiety and postoperative pain in children undergoing adenotonsillectomy.
Material and methods

In this cross-sectional study 156 children undergoing adenotonsillectomy involved. Patients’ blood glucose levels were measured at different times. In order to assess the anxiety and restlessness of children, the Anxiety Scale of m-YPAS (Modified Yale Preoperative Anxiety Scale) was used. To evaluate the children’s postoperative pain, VAS (visual analog scale) was used before feeding after the surgery.
Results

Mean of patients’ blood glucose levels was (92.63 ± 9.33) 15 minutes before the surgery, (87.26 ± 8.32) 15 minutes after the surgery and (85.17 ± 1.3) before feeding after the surgery. The results showed no significant correlation between mean anxiety score and mean blood glucose level at different times. There was a significant correlation between mean pain score and blood glucose level measured 15 minutes after the surgery (p-value = 0.004) but showed no significant correlation 15 minutes before the surgery (p-value = 0.29) and also before feeding after the surgery (p-value = 0.240).
Conclusion

According to our results, since there was only a significant correlation between mean pain score and blood glucose level measured 15 minutes after the surgery (not between the other different times) and over time, due to the body's natural analgesic mechanisms this effect is reduced, it can be concluded that it is not rational to advise hyperglycemic solutions and serums containing glucose in children undergoing adenotonsillectomy.
Increased Occurrence of PTSD Symptoms in Adolescents with Major Depressive Disorder Soon After the Start of the COVID-19 Outbreak in China: a Cross-Sectional Survey
Authors: Zhang Hang , Xu Hanmei , Huang Lijuan , Wang Xiaolan , Tang Xiaowei , Wang Yanping , Deng Fang , Wang Wo , Tao Yuanmei , Yin Li 
Published: February 2021

Abstract
ObjectiveThe Coronavirus Disease 2019 (COVID-19) pandemic continues to threaten the physical and mental health of people across the world. This study aimed to understand the psychological impact of this disease on adolescents with major depressive disorder (MDD) at one month after the start of the outbreak in China.MethodsUsing the Children's Impact of Event Scale (CRIES-13) questionnaire, we investigated the occurrence of posttraumatic stress disorder (PTSD) in two groups of adolescents: MDD patients who were in stable condition with antidepressant therapy and healthy controls. Total scores and factor subscores were compared between the two groups and subgroups stratified by sex and school grade. Logistic regression was used to identify variables associated with high total CRIES-13 scores.ResultsCompared to controls (n = 107), the MDD group (n = 90) had higher total CRIES-13 scores and a higher proportion with a total score ≥ 30. They also had a lower intrusion subscore and a higher arousal subscore. In the MDD group, males and females did not differ significantly in total CRIES-13 scores or factor subscores, but junior high school students had higher avoidance subscores than senior high school students. Logistic regression showed high total CRIES-13 scores to be associated with MDD and the experience of “flashbacks” or avoidance of traumatic memories associated with COVID-19.ConclusionsIt is crucial to understand the psychological impact of COVID-19 on adolescents with MDD in China, especially females and junior high school students. Long-term monitoring of adolescents with a history of mental illness is required to further understand these impacts.Trial registrationChiCTR, ChiCTR2000033402, Registered 31 May 2020, http://www.chictr.org.cn/index.aspx
Posttraumatic stress disorder correlates among Iraqi internally displaced persons in Duhok, Iraqi Kurdistan
Authors: Taha Perjan Hashim , Taib Nezar Ismet , Sulaiman Hushyar Musa 
Published: February 2021

Abstract
BackgroundIn 2014, the terrorist militant group the Islamic State of Iraq and Syria (ISIS) took over one-third of Iraq. This study measured the rate of posttraumatic stress disorder (PTSD) among Iraqi internally displaced persons (IDPs) and examined associated demographic and traumatic risk factors and comorbid psychiatric symptoms.MethodsA cross-sectional survey was carried out in April-June 2015 at the Khanke camp, northern Iraq. Trauma exposure and PTSD were measured by the Harvard Trauma Questionnaire (Iraqi version), and psychiatric comorbidity was measured by the General Health Questionnaire (GHQ-28).ResultsOf 822 adult IDPs, 33.8% screened positive for PTSD. Associated factors included exposure to a high number of traumatic events, unmet basic needs and having witnessed the destruction of residential or religious areas. Being a widow was the only linked demographic factor (OR = 14.56, 95% CI: 2.93–72.27). The mean scores of anxiety/insomnia and somatic symptoms were above the average cutoff means (M = 3.74, SD = 1.98, R = 0–7 and M = 3.69, SD = 2.14, R = 0–7, respectively) among the IDPs with PTSD.ConclusionsHigh traumatic exposure, specifically unmet basic needs and having witnessed destruction, was an important predictor of PTSD among IDPs. Psychiatric comorbidity was high among those with PTSD. Anxiety, insomnia and somatic symptoms were strongly associated with PTSD. These findings are important for mental health planning for IDPs in camps.Clinical trial registrationNot applicable.
Correlation of periodontal diseases with intracranial aneurysm formation: novel predictive indicators
Authors: Liu Keyun , Sun Jia , Shao Lingling , He Hongwei , Liu Qinglin , Li Youxiang , Ge Huijian 
Published: February 2021

Abstract
Background and purpose: We investigated whether periodontal diseases, specifically, periodontitis and gingivitis, could be risk factors of the incidence of intracranial aneurysms (IAs).Methods: We performed a case–control study to compare the differences in the periodontal disease parameters of 281 cases that were divided into the IAs group and non-IAs group. All cases underwent complete radiographic examination for IAs and examination for periodontal health. Results: Comparing with those in the non-IAs group, the cases in the IAs group were older (53.95 ± 8.56 vs 47.79 ± 12.33, p < 0.001) and had a higher incidence of hypertension (76 vs 34, p = 0.006). Univariate logistic regression analysis revealed that age (>50 years) and hypertension were predictive risk factors of aneurysm formation (odds ratio [OR] 1.047, 95% confidence interval [95%CI] 1.022–1.073, p < 0.001 and OR 2.047, 95%CI 1.232–3.401, p = 0.006). In addition, univariate and multivariate logistic regression analyses showed that the parameters of periodontal diseases, including gingival index, plaque index, clinical attachment loss, and alveolar bone loss, were significantly associated with the occurrence of IAs (all p < 0.05). For further statistical investigation, the parameters of periodontal diseases were divided into four layers based on the quartered data. Poorer periodontal health condition (especially gingival index＞1.1 and plaque index＞1.5) had the correlation with IAs formation (p＝0.007 and p＜0.001). Conclusion: Severe gingivitis or periodontitis combining with hypertension, are significantly associated with the incidence of IAs.
Does the gap between health workers’ expectations and the realities of implementing a Performance-Based Financing project in Mali create frustration?
Authors: Zitti Tony , Fillol Amandine , Lohmann Julia , Coulibaly Abdourahmane , Ridde Valéry 
Published: February 2021

Abstract
Background: Performance-Based Financing (PBF), an innovative health financing initiative, was recently implemented in Mali. PBF aims to improve quality of care by motivating health workers. The purpose of this research was to identify and understand how health workers’ expectations related to their experiences of the first cycle of payment of PBF subsidies, and how this experience affected their motivation and sentiments towards the intervention. We pose the research question, “how does the process of PBF subsidies impact the motivation of health workers in Mali?”Methods: We adopted a qualitative approach using multiple case studies. We chose three district hospitals (DH 1, 2 and 3) in three health districts (district 1, 2 and 3) among the ten in the Koulikoro region. Our cases correspond to the three DHs. We followed the principle of data source triangulation; we used 53 semi-directive interviews conducted with health workers (to follow the principle of saturuation), field notes, and documents relating to the distribution grids of subsidies for each DH. We analyzed data in a mixed deductive and inductive manner.Results: The results show that the PBF subsidies led to health workers feeling more motivated to perform their tasks overall. Beyond financial motivation, this was primarily due to PBF allowing them to work more efficiently. However, respondents perceived a discrepancy between the efforts made and the subsidies received. The fact that their expectations were not met led to a sense of frustration and disappointment. Similarly, the way in which the subsidies were distributed and the lack of transparency in the distribution process led to feelings of unfairness among the vast majority of respondents. The results show that frustrations can build up in the early days of the intervention.Conclusion: The PBF implementation in Mali left health workers frustrated. The short overall implementation period did not allow actors to adjust their initial expectations and motivational responses, neither positive nor negative. This underlines how short-term interventions might not just lack impact, but instil negative sentiments likely to carry on into the future.
Blending Cognitive Analytic Therapy With a Digital Support Tool: Mixed Methods Study Involving a User-Centered Design of a Prototype App
Authors: Easton Katherine , Kellett Stephen , Cooper Martin , Millings Abigail , Varela Jo , Parry Glenys 
Published: February 2021

Background
Patients can struggle to make good use of psychotherapy owing to deficits in awareness, and digital technologies that support awareness are at a premium. Currently, when patients participate in cognitive analytic therapy (CAT), the technology supporting relational awareness work involves completion of paper-based worksheets as between-session tasks.

Objective
We aimed to design, with therapists and patients, a prototype digital mobile app. This was to help patients better engage in the “recognition” phase of the CAT treatment model by providing an unobtrusive means for practicing relational awareness with dynamic feedback on progress.

Methods
A national online survey was conducted with CAT therapists (n=50) to determine readiness for adoption of a mobile app in clinical practice and to identify core content, functionality, and potential barriers to adoption. A prototype mobile app based on data and existing paper-based worksheets was built. Initial face-to-face user testing of the prototype system was completed with three therapists and three CAT expatients.

Results
Among the therapists surveyed, 72% (36/50) reported not currently using any digital tools during CAT. However, the potential value of a mobile app to support patient awareness was widely endorsed. Areas of therapist concern were data security, data governance, and equality of access. These concerns were mirrored during subsequent user testing by CAT therapists. Expatients generated additional user specifications on the design, functionality, and usability of the app. Results from both streams were integrated to produce five key changes for the reiteration of the app.

Conclusions
The user-centered design process has enabled a prototype CAT-App to be developed to enhance the relational awareness work of CAT. This means that patients can now practice relational awareness in a much more unobtrusive manner and with ongoing dynamic feedback of progress. Testing the acceptability and feasibility of this technological innovation in clinical practice is the next stage in the research process, which has since been conducted and has been submitted. The important challenges of data protection and governance must be navigated in order to ensure implementation and adoption if the CAT-App is found to be acceptable and clinically effective.
Notas para una ética de la improvisación (una aproximación desde la ecología del sujeto
Authors: Rodriguez Federico 
Published: February 2021

El presente artículo tratará de cernir un campo en el que términos como ética, ecología e improvisación puedan entrelazarse para formular un ethos de la práctica de la música improvisada. Para esto reúne tres hilos teóricos diferentes: la ecosofía, la ética y la autoafirmación, tomados de las ideas de Félix Guattari, Cornelius Cardew y Steve Coleman. Más que un sistema de reglas, este escrito aproxima la posibilidad de pensar una ecología del sujeto a través de la práctica de la improvisación musical.
PENERJEMAHAN KALIMAT IMPERATIF DAN KESALAHANNYA DALAM KITAB AR RAḤĪQ AL MAKHTŪM KARYA SYAIKH SHAFIYYURRAHMAN AL MUBARAKFURI
Authors: Anis Muhammad Yunus , Ash-Shidiqiyyah Firstiyana Romadlon 
Published: February 2021

This research analyzes the translation of imperative sentences in Ar Raḥīq Al Makhtūm book (2007) by Shaikh Shafiyyurahman Al Mubarakfuri which was created to participate in a scientific competition on sirah nabawiyah in Pakistan. The book was translated into Indonesian by Kathur Suhardi as Sirah Nabawiyah (2014), a translator graduating from a boarding school who has published several translated books from any sciences. This research aims to describe the translation and its errors that applied by translator on translating imperative sentences in Ar Raḥīq Al Makhtūm book. The translation of imperative sentences is divided into two parts, the translation of positive imperative sentences (84%) and the translation of negative imperative sentences (16%), while that translation errors of imperative sentence are divided into four parts among them, linguistic category errors (28%), surface strategy errors (16%), comparative analysis errors (8%) and communicative effect errors (48%). The research methodology was qualitative descriptive research, an analysis that carried out from collecting data by the observation method of reading, understanding and signing of imperative sentences so be able to distinguish between imperative sentences with others. After collecting the data, then classifies the data according to categories and presents all data regarding the translation and its errors of imperative sentences and finally making the conclusions based on data that has been found. It was found there were 103 imperative sentence translation data with 87 positive imperative sentence translation data and 16 negative imperative sentence translation data, while for translation errors of imperative sentence researcher founds 50 data with 14 data in linguistic category errors, 8 data in the surface strategy errors, 4 data in comparative analysis errors and 24 data in communivative effect errors.