bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between DBT network training and perceived criticism: a pre-post study
Authors: Leeuwen Hanneke van , Bosch Wies van den , Ossewaarde Lindsey , Egger Jos 
Published: January 2021

Abstract
Background: Emotional and behavioural dysregulation in patients with Borderline Personality Disorder (BPD), such as repeated non-suicidal self-injury, are strongly affecting patients’ family members or partners. In addition, critical disapproval of this emotional and behavioural phenomena by family members and reconciling understanding, affects the patients’ sensitivity for rejection. As a result, scientific findings endorse that individuals with BPD appear to experience less satisfying social support and a stronger feeling of loneliness. This negative spiral possibly elicits further challenging behaviour. Therapy programs for BPD might therefore benefit from the inclusion of family members or partners in the treatment. One of the programs that includes family members is the network training of Dialectical Behavior Therapy (DBT). This study examines the impact of the DBT network training on the perceived criticism of both patients and network members.Method: This study follows a pre-post design where a DBT network training is given to 33 patients (mean age 25 years) and 61 relatives during 8 group sessions. The degree of perceived criticism is measured by using a self-report questionnaire.Results: Results show that the overall scores of the perceived criticism scale decrease significantly for both patients and relatives after following the DBT network training. More specific, item scores of both patients and relatives concerning how critical they looked towards the other and how critical they thought the other looked at them also decreased significantly after following the DBT network training. Conclusion: Findings suggest that a DBT network training may be instrumental in decreasing levels of perceived criticism. Further research may focus on the putative mechanisms of behaviour such as improved perspective taking, behavioural change, and the evaluation of social cues.
Clinical characteristics and outcome of influenza virus infection among adults hospitalized with severe COVID-19: A retrospective cohort study from Wuhan, China
Authors: Tong Xunliang , Xu Xiaomao , Lv Guoyue , Wang He , Cheng Anqi , Wang Dingyi , Fan Guohui , Zhang Yue , Li Yanming 
Published: January 2021

Abstract
BackgroundCoronavirus disease 2019 (COVID-19) is an emerging infectious disease that rapidly spreads worldwide and co-infection of COVID-19 and influenza may occur in some cases. We aimed to describe clinical features and outcomes of severe COVID-19 patients with co-infection of influenza virus.MethodsRetrospective cohort study was performed and a total of 140 patients with severe COVID-19 were enrolled in designated wards of Sino-French New City Branch of Tongji Hospital between Feb 8th and March 15th in Wuhan city, Hubei province, China. The demographic, clinical features, laboratory indices, treatment and outcomes of these patients were collected.ResultsOf 140 severe COVID-19 hospitalized patients, including 73 patients (52.14%) with median age 62 years were influenza virus IgM-positive and 67 patients (47.86%) with median age 66 years were influenza virus IgM-negative. 76 (54.4%) of severe COVID-19 patients were males. Chronic comorbidities consisting mainly of hypertension (45.3%), diabetes (15.8%), chronic respiratory disease (7.2%), cardiovascular disease (5.8%), malignancy (4.3%) and chronic kidney disease (2.2%). Clinical features, including fever (≥38°C), chill, cough, chest pain, dyspnea, diarrhea and fatigue or myalgia were collected. Fatigue or myalgia was less found in COVID-19 patients with IgM-positive (33.3% vs 50/7%, P = 0.0375). Higher proportion of prolonged activated partial thromboplastin time (APTT) > 42 s was observed in COVID-19 patients with influenza virus IgM-negative (43.8% vs 23.6%, P = 0.0127). Severe COVID-19 Patients with influenza virus IgM positive have a higher cumulative survivor rate than that of patients with influenza virus IgM negative (Log-rank P= 0.0308). Considering age is a potential confounding variable, difference in age was adjusted between different influenza virus IgM status groups, the HR was 0.29 (95% CI, 0.081-1.100). Similarly, difference in gender was adjusted as above, the HR was 0.262 (95% CI, 0.072-0.952) in the COX regression model.ConclusionsInfluenza virus IgM positive may be associated with decreasing in-hospital death.
Establishment of an evaluation index system of competencies for graduating students in general practice medicine
Authors: Zhao Rui , Liu Feng , Zhu Kun 
Published: January 2021

Abstract
Background: The competencies of graduating students in general practice medicine have attracted attention. This study aimed to construct an evaluation index system of competencies for graduating students in general practice medicine and to promote the reform and optimization of training programs for general medicine talent in colleges.Methods: The two-round Delphi method was used to determine the evaluation index system of competencies for graduating students in general practice medicine, and the analytic hierarchy process (AHP) was used to calculate the weights of all levels of elements.Results: The evaluation index system of competencies for graduating students in general practice medicine was established with 3 primary factors, 9 secondary factors and 32 tertiary factors. The Delphi results revealed that the active coefficient of experts was 1 and the authority coefficient was 0.858. The 3 primary factors were knowledge level, job skills and professionalism with weights of 0.1532, 0.4207 and 0.4261, respectively. Among the secondary factors, the top three weight coefficients were professional ethics (0.2614), community practice (0.1526) and communication skills (0.1308). Among tertiary factors, "scientific research" exhibited the lowest value with a weight coefficient of 0.0049.Conclusion: In this study, we constructed an evaluation index system of competencies for graduating students in general practice medicine. The consensus on the content of the competencies of graduating students in general practice medicine suggests that these elements are necessary for those who will become general practitioners. This system can be used as the basis to evaluate the ability of graduating students in general practice medicine and provide guidance for the cultivation and evaluation of general medicine talent.
Intraoperative Hemodynamic Optimization Using The Hypotension Prediction Index And Its Impact Of Tissular Perfusion. Protocol For The Predict H Trial
Authors: Olazábal Juan Victor Lorente , Jiménez Ignacio , Ripollés-Melchor Javier , Becerra Alejandra Isabel , Wesselink Wilbert , Reguant Francesca , Mojarro Irene , Fuentes Maria de los Ángeles , Abad-Motos Ane , Agudelo Elizabeth , Machancoses Francisco H. , Callejo Paula , Bosch Joan , García Manuel Ignacio Monge 
Published: January 2021

Abstract
Background: Intraoperative arterial hypotension is associated with poor postoperative outcomes. The Hypotension Prediction Index, developed from machine learning, predicts the occurrence of arterial hypotension from the analysis of the arterial pressure waveform. The use of this index can reduce the duration and severity of intraoperative hypotension in adults undergoing noncardiac surgery.Methods: We will conduct a multicenter, randomized, controlled trial (N=80) in high-risk surgical patients scheduled for elective major abdominal surgery. All participants will be randomly assigned to a control or intervention group. Hemodynamic management in the control group will be based on standard hemodynamic parameters. Hemodynamic management of patients in the intervention group will be based on functional hemodynamic parameters provided by the HemoSphere platform (Edwards Lifesciences Corp.), including dynamic arterial elastance, dP/dtmax and the Hypotension Prediction Index. Tissue oxygen saturation will be non-invasively and continuously recorded by using near-infrared spectroscopy technology. Biomarkers of acute kidney stress (cTIMP2 and IGFBP7) will be obtained before and after surgery. The primary outcome will be intraoperative time-weighted average of a mean arterial pressure < 65mmHg.Discussion: The aim of the study is to determine whether a goal-directed algorithm based on the prevention of arterial hypotension using the Hypotension Prediction Index reduces the duration and severity of intraoperative hypotension when compared with the recommended standard therapy and if this intraoperative strategy is associated with better tissue oxygenation and organ perfusion. Trial registration: ClinicalTrials.gov, NCT04301102. Registered on March 10, 2020.
Time Series Analyses and Modeling of Environmental Systems: Case Studies in Kuwait
Authors: Alhumoud Jasem M. , Almeshaan Nourah 
Published: January 2021

Background:Time series is a sequence of measurements made at regular time intervals. Tremendous work has been done on pipe break investigation and maintenance, using different models. However, the authors have not found any research work on pipe failures in water distribution networks using time series.Objective:The principal objective of this paper was to investigate the applications of time series analysis in modeling man-made (pipe breaks) and natural (rainfall) environmental systems.Methods:This objective was satisfied by employing the Time-Domain (Box-Jenkins) approach to assess two case studies in Kuwait of a water distribution network (pipe failures), and from rainfall rates measurement of a solid waste disposal site, respectively. The statistical analysis of these data was conducted with the aid of the BMDP and SAS computer software packages and by the use of the P2T programming procedure for the Box-Jenkins method.Results:The results showed a significant correlation between the data and the time series models provides good estimates of pipe reliability and rainfall measurements.Conclusion:Based on the significant results, time series analyses could and should be useful by water authorities in planning pipe maintenance and inspection. Moreover, it is recommended and it would be very useful to conduct similar studies on pipes carrying other fluids such as gas, air and oil.
Deep Learning Models for Predicting Severe Progression in COVID-19-Infected Patients: Retrospective Study
Authors: Ho Thao Thi , Park Jongmin , Kim Taewoo , Park Byunggeon , Lee Jaehee , Kim Jin Young , Kim Ki Beom , Choi Sooyoung , Kim Young Hwan , Lim Jae-Kwang , Choi Sanghun 
Published: January 2021

Background
Many COVID-19 patients rapidly progress to respiratory failure with a broad range of severities. Identification of high-risk cases is critical for early intervention.

Objective
The aim of this study is to develop deep learning models that can rapidly identify high-risk COVID-19 patients based on computed tomography (CT) images and clinical data.

Methods
We analyzed 297 COVID-19 patients from five hospitals in Daegu, South Korea. A mixed artificial convolutional neural network (ACNN) model, combining an artificial neural network for clinical data and a convolutional neural network for 3D CT imaging data, was developed to classify these cases as either high risk of severe progression (ie, event) or low risk (ie, event-free).

Results
Using the mixed ACNN model, we were able to obtain high classification performance using novel coronavirus pneumonia lesion images (ie, 93.9% accuracy, 80.8% sensitivity, 96.9% specificity, and 0.916 area under the curve [AUC] score) and lung segmentation images (ie, 94.3% accuracy, 74.7% sensitivity, 95.9% specificity, and 0.928 AUC score) for event versus event-free groups.

Conclusions
Our study successfully differentiated high-risk cases among COVID-19 patients using imaging and clinical features. The developed model can be used as a predictive tool for interventions in aggressive therapies.
Pengaruh stres kerja terhadap kepuasan hidup pada buruh garmen perempuan di Cicurug Kabupaten Sukabumi
Authors: Al Akbar Multazam , Vinaya Vinaya 
Published: January 2021

Objektif: Banyaknya industri pengolahan garmen yang ada di Cicurug, Kabupaten Sukabumi membuat sebagian besar perempuan di sana bekerja di pabrik garmen. Salah satu masalah pekerjaan yang dialami oleh buruh di Cicurug adalah target kerja dan jam kerja yang berlebihan. Masalah tersebut sering menjadi pemicu stress sehingga terkadang berdampak pada kepuasan hidup terutama pada buruh garmen perempuan yang sudah menikah. Penelitian ini bertujuan untuk mengetahui apakah ada pengaruh stres kerja terhadap kepuasan hidup pada buruh garmen perempuan di Cicurug, Kab. Sukabumi.Metode: Penelitian ini menggunakan pendekatan kuantitatif dengan menggunakan kuesioner. Alat ukur yang digunakan untuk mengukur stres kerja dari Parker dan DeCotiis (1983) dan untuk mengukur kepuasan hidup dari Diener dan Pavrot (dalam Diener, 2008). Sampel penelitian ini adalah 152 buruh garmen perempuan yang sudah menikah. Teknik sampel yang digunakan pada penelitian ini adalah accidental sampling. Metode analisis data dengan menggunakan analisis regresi linear sederhana.Temuan: Hasil pengolahan data menujukkan bahwa stres kerja tidak berpengaruh terhadap kepuasan hidup buruh garmen di Cicurug, Kab. Sukabumi. Penelitian ini menemukan bahwa sebagian besar responden buruh garmen wanita memiliki tingkat stress kerja yang rendah dan tingkat kepuasan hidup yang juga rendah.Kesimpulan: Hipotesis penelitian diterima.
Physical properties of soil in the early stage of an agroforestry system in the High Andean zone
Authors: Muñoz-Rodríguez Martin Alonso , Delgado-Vargas Iván Andrés , Guerrero Jennyfer Cristina , Andrade Anyi Valeria 
Published: January 2021

In Nariño, Colombia, land use has generated some problems such as erosion, compaction, lack of fertility, among others, so it is necessary to search for alternatives to mitigate these impacts. The objective of this study was to evaluate some physical properties of the soil in an agroforest system with Morella pubescens (Humb. & Bonpl. ex Willd.) Wilbur with Smallanthussonchifolius (Poepp.) H.Rob, in the experimental farm of Botana, in the city of Pasto, Nariño, where the bulk density, real density, total porosity, structural stability properties and distribution of aggregates were analyzed. The datas were obtained in two phases: f1 and f2 before and after agroforestry system implementation, respectively. A randomized complete block design with three treatments and three replications were used. The treatments corresponded to plant densities, T1: S sonchifoliuos, sowed to 1x1m, T2:0.8x0.8m y T3:0.5x0.5m, with three replications. M pusescens was stablished to 4x4m between plants and 9 m between rows and the control (f1). The statistics have differences between f1 (control) and f2 (treatments), to the structural stability properties and distribution of aggregates. The ground suffered a structural stability change to stable lightly (0.97 D.P.M) in f1 to a stable moderate (2.53 D.P.M), in f2. The distribution of aggregates passed to 60% in f1 to 70.3% in f2, with a media aggregation status. The different agroforest systems management could help, in the long term, by improving the structure of the ground through the vegetal material of arboreal component, the application of a minimum farming and the addition of organic matter.
Effect of supplementation with organic acids on productive and reproductive parameters in guinea pigs
Authors: Vela Christian , Morales-Cauti Siever 
Published: January 2021

Guinea pig production systems demand organic alternatives to improve their productivity, due to the increased demands of this type of livestock operations. The present study aimed to evaluate the effect of organic acids on the productive and reproductive indices in reproductive Guinea pigs in an intensive breeding farm in Lima. 60 pools were used with 10 Guinea pigs in each one (9 females and one male). They were randomly divided into 4 treatment groups: T1: 1mL/L, T2: 2mL/L, T3: 4mL/L; all with 15 pools in total (5 pools each with dosage of 5, 10 and 15 days, respectively), and T4: Control (15 pools without dosage); the observation period was 3 months. No significant difference was found (p> 0.05) between treatments for weight gain, percentage of maternal mortality, percentage of abortions, percentage of pregnancy, number of offspring born and percentage of viability. For the percentage of mortality of pups and average weight of the offspring, a significant difference was found (p <0.05), demonstrating that T3 reached a higher weight index at birth of offspring (T3: 147.7 / 142.7 / 146.8g) and lower percentage of mortality in rabbits (T3: 0 / 1.8 / 3.0%). No significant difference was found in terms of dosing days. It is concluded that supplementation with organic acids with T3 (4mL/L) improved the weight at birth of the offspring and the mortality percentage in kits.
Vem para a rua: convite a uma nova forma de experimentar a cidade.
Authors: Espindola dos Santos Mariana 
Published: January 2021

Este artigo tem como intuito elaborar uma explanação sobre as formas de conhecer a cidade, tomando como norte da pesquisa o convite a vivenciar os espaços urbanos como artistas visuais e ativistas. Os projetos Stop Telling Women To Smile e o Coletivo Feminicidade promovem uma convocação aos seus seguidores de se tornar ativista. Para a elaboração deste artigo, a pesquisa acompanhou as redes sociais dos artistas, além de uma observação participativa nas oficinas e nas colagens proporcionadas pelo Coletivo Feminicidade. A experiência proporcionou uma reflexão maior sobre a interação de artistas e ativistas com seus públicos para além das redes sociais, contribuindo para diálogos sobre as suas xperiências em pensar como seus corpos interagem em grandes centros urbanos.
Comment ne pas etre "pigeonholed"; l'ethos entrepreneurial (Como não ser um pombo engaiolado; o ethos empresarial)
Authors: Maingueneau Dominique 
Published: January 2021

Dans une perspective d'analyse du discours, cet article aborde un ethos collectif particulièrement important dans le monde contemporain: l'ethos "entrepreneurial" qui est censé animer les acteurs les plus prestigieux et les plus dynamiques de l'économie, en particulier ceux qui travaillent dans le monde des "start-up". L'exposé s'articule autour de l'étude de trois textes (un journal quotidien, une publicité pour une école, un magazine pour cadres) qui participent de la représentation médiatique de cet ethos et dont le public cible appartient au monde du business. L'analyse prend pour fil directeur le terme anglais "pigeonholed", qui caractérise l'anti-ethos que doit à tout prix rejeter le bon entrepreneur. Elle s'appuie, pour cela, sur le discours prescriptif des professionnels du conseil en management, qui façonnent le discours partagé par l'ensemble des acteurs de ce monde. L'étude débouche sur une réflexion sur les affinités entre discours religieux et discours économique en matière d'incorporation d'ethos.
Management of Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma
Authors: Macedo Francis Igor , Yakoub Danny , Dudeja Vikas , Merchant Nipun B. 
Published: January 2021

The incidence of pancreatic cancer continues to rise, and it is now the third-leading cause of cancer-related deaths in the United States. Only 15 to 20% of patients are eligible to undergo potentially curative resection, as most tumors are deemed unresectable at the time of diagnosis because of either locally advanced disease or distant metastases. Improvements in preoperative CT imaging have enabled better determination of the extent of disease and allowed for better operative planning. Based on their relationship to the surrounding vasculature and structures and presence or absence of distant disease, pancreatic tumors are classified into four categories: resectable, borderline resectable pancreatic cancer (BRPC), locally advanced pancreatic cancer (LAPC), and metastatic. With the recent advent of more effective chemotherapy regimens, efforts have focused on using neoadjuvant therapy approaches to increase the likelihood of achieving an R0 in patients with BRPC and possibly convert unresectable, locally advanced tumors to potentially resectable tumors. Response with neoadjuvant therapy regimens has resulted in increased number of patients eligible for resection, many times requiring vascular resection. Herein, we describe recent changes in the classification, important surgical and pathologic considerations and updated multimodal therapeutic options in the complex management of BRPC and LAPC.
This review contains 5 figures, 2 tables, and 78 references.
Key Words: borderline resectable pancreatic cancer, CA 19-9, FOLFIRINOX, locally advanced pancreatic cancer, nab-paclitaxel, neoadjuvant chemotherapy, pancreatectomy, portal vein resection, radiation therapy, gemcitabine
Noninvasive Hemodynamic Monitoring in the ICU
Authors: Johnson Timothy G , Hopper Herbert. A. , May Addison K 
Published: January 2021

The primary goal of hemodynamic monitoring in critically ill patients is to enable and direct targeted interventions to restore or maintain adequate cellular perfusion. Inadequate cellular perfusion defines a state of shock and propagates preexisting cellular injury, whether or not shock is overt or occult. Tissue perfusion is determined through a complex relationship between perfusion pressure and cardiac output. The goal of hemodynamic monitoring is to aid in determining which of these parameters should be altered to improve perfusion while limiting potential deleterious effects that these interventions may introduce. In today’s modern ICU, the critical care physician has access to multiple tools and equipment designed to elucidate the type of shock and guide treatment. Technologic advancements have led to less invasive methods of defining the physiologic picture of patients. This includes everything from the invasive pulmonary artery catheter to echocardiography and arterial wave form calculation. However, each of these modalities comes with its own advantages and disadvantages. Furthermore, one also has to factor in the cost of the device and the associated training required for the practitioner. This review examines the most commonly used non-invasive monitoring modalities used in clinical practice and offers an overview of each device.
This review contains 6 figures, 3 tables, and 95 references.
Key Words: bioimpedance, echocardiography, ImaCor, LiDCO, NICO, noninvasive monitoring, PiCCO, pulmonary artery catheter, pulse contour
Colitis: Infectious, Ischemic, and Toxic Megacolon
Authors: Dyer Mitchell , Zuckerbraun Brian S. 
Published: January 2021

Colitis is a common gastrointestinal illness that carries high morbidity and mortality in critically ill patients admitted to the intensive care unit. In critically ill patients, colitis can be a primary process or secondary result from their presenting illness. The etiology of the colitis ranges from infectious (bacterial, viral, and the most common gastrointestinal infection hospitalized patients Clostridium difficile), ischemic insult (both occlusive and nonocclusive disease), and finally inflammatory bowel disease. This chapter goes over the background, work-up and diagnosis, and finally treatment options and strategies for the most common etiologies that afflict this population of severely ill patients.
This review contains 3 figures, 6 tables, and 79 references.

Keywords:colectomy, colitis, diarrhea, fecal transplant, hematochezia, ischemia, inflammation, vancomycin, Clostridium difficile