bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENERAPAN MODEL ALTMAN Z-SCORE DALAM MENGUKUR POTENSI KEBANGKRUTAN (STUDI KASUS PADA PERUSAHAAN PERBANKAN BUMN YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2018 & 2019)
Authors: Rofinus Leki Rofinus Leki 
Published: September 2021

Abstract: This research is a sustainability research, which uses the same non- manufacturing Altman Z-Score model, with the aim of re-examining the financial health sustainability of the four BUMN banks that the author has studied in 2017 and in 2019. The four BUMN banks are Bank Negara Indonesia (Persero) Tbk PT, Bank Rakyat Indonesia (Persero) Tbk. PT, Bank Tabungan Negara (Persero) Tbk PT, Bank Mandiri (Persero) Tbk PT. The results showed that PT. Bank BTN (Persero) Tbk has a Z-score that has improved in 2018 and 2019, compared to previous years, namely in 2014, 2015, 2016, and 2017. Currently PT. Bank BTN (Persero) Tbk., has moved from the potential financial distress into a "gray area" (improving). Meanwhile, the other three BUMN banks are consistently in the gray area category with a Z-score above 1.2 but below a Z-score of 2.9. The results of this study also show that there is a significant financial performance improvement in every BUMN banking company, but has decreased somewhat in
2019 at Bank BNI (Persero), Tbk. PT and Bank BRI (Persero) Tbk.PT. Be expected is that with the continuous and consistent improvement in financial performance, the financial health position of BUMN Banking (Persero) Tbk can immediately move to the "safe zone".

Keywords: Financial Health of BUMN Banks, Altman Z-Score Model
Nilai-Nilai Coworking Space dalam Mendukung Konsep Kota Kreatif (Studi Kasus: Daerah Istimewa Yogyakarta)
Authors: Ni'mah Mahnunah  
Published: September 2021

Globalisasi dan perkembangan teknologi informasi dan komunikasi membawa perekonomian dunia saat ini telah memasuki era ekonomi kreatif, yang memberikan implikasi pada pengembangan konsep kota kreatif dalam perencanaan dan pengembangan kota. Daerah Istimewa Yogyakarta sebagai kota yang telah dikenal menjadi pusat budaya dan pendidikan didalamnya memiliki sumber daya utama kota kreatif yaitu orang-orang kreatif. Penerapan konsep kota kreatif yang dapat dilihat dari aspek fisik yaitu keberadaan ruang-ruang kreatif yang salah satunya berupa coworking space. Coworking space sebagai wadah dalam menumbuhkan kembangkan kreativitas dan inovasi orang-orang kreatif. Penelitian ini bertujuan untuk mengkaji nilai – nilai coworking space dalam mendukung konsep kota kreatif dengan menggunakan studi kasus di Daerah Istimewa Yogyakarta. Penelitian ini menggunakan pendekatan kualitatif dengan metode analisis deskriptif kualitatif menggunakan studi kasus. Hasil penelitian menunjukkan bahwa nilai-nilai coworking space di Daerah Istimewa Yogyakarta sebagai lingkungan kerja di sektor kreatif mampu mendorong munculnya komunitas, kolaborasi, komunikasi, dan kreativitas dapat berkontribusi dalam menghasilkan inovasi dan penciptaan peluang nilai ekonomi. Keberadaan coworking space di kota ini juga memiliki peranan yang signifikan dalam hal menghasilkan orang-orang kreatif atau pekerja kreatif (creative class) sebagai sumber daya utama dalam pengembangan kota kreatif.
Perceptual stimuli with novel bindings interfere with visual working memory
Authors: Shepherdson Peter 
Published: September 2021

AbstractWhat influences the extent to which perceptual information interferes with the contents of visual working memory? In two experiments using a combination of change detection and continuous reproduction tasks, I show that binding novelty is a key factor in producing interference. In Experiment 2, participants viewed arrays of colored circles, then completed consecutive change detection and recall tests of their memory for stochastically independent items from the same array. When the probe used in the change detection test was novel (i.e., required a “change” response), subsequent recall performance was worse than in trials with matching (i.e., “no change”) probes, irrespective of whether or not the same item was tested in both phases. In Experiment 2, participants viewed arrays of oriented arrows, then completed a change detection (requiring memory) or direction judgement (not requiring memory) test, followed by recalling a stochastically independent item. Again, novel probes in the first phase led to worse recall, irrespective of whether the initial task required memory. This effect held whether the probe was wholly novel (i.e., a new feature presented at any location) or simply involved a novel binding (i.e., an old feature presented at a new location). These findings highlight the role of novelty in visual interference, consistent with the assumptions of computational models of WM, and suggest that new bindings of old information are sufficient to produce such interference.
La racialisation des patient·e·s « roms » par les médecins urgentistes
Authors: Prud’homme Dorothée 
Published: September 2021

Cet article met au jour la racialisation à laquelle procèdent les médecins urgentistes envers des patient·e·s qu’elles et ils identifient comme roms – soit des patient·e·s perçu·e·s comme conjuguant altérité « ethno-raciale » et précarités socio-économique, résidentielle et administrative – expliquant par « leur différence culturelle » leurs motifs de recours aux services d’urgences. Ces motifs sont pourtant identiques à ceux invoqués par la majorité des publics de ces services eux aussi caractérisés par leurs conditions économiques, résidentielles ou administratives précaires. L’analyse de la conception que les ugentistes se font de leurs missions professionnelles et des enjeux de rentabilité financière que les réformes du new public management imposent à ces services, révèle les usages fonctionnels de la racialisation. En invisibilisant leur précarité socio-économique, administrative ou résidentielle, la racialisation des patient·e·s « roms » permet ainsi aux médecins urgentistes des hôpitaux publics de valoriser la réalisation de prouesses médicales au détriment de tâches susceptibles de mener à leur déclassement professionnel.
Presencia de Nacerdes (Xanthochroa) raymondi (Mulsant & Godart, 1860) (Coleoptera, Oedemeridae) en el Magreb occidental (Norte de África)
Authors: Ruiz José L. , García-París Mario 
Published: September 2021

Se informa de la presencia de una población establecida de Nacerdes (Xanthochroa) raymondi en la Ciudad Autónoma de Ceuta (España, extremo septentrional de la península Tingitana). Este nuevo registro confirma la presencia de N. (X.) raymondi en el Magreb occidental, tras más de medio siglo sin datos al respecto. La presencia de N. (X.) raymondi en Ceuta extiende su distribución norteafricana hacia el noroeste, completando el vacío de registros entre las poblaciones argelinas e ibéricas, y apoya la veracidad de dos antiguas citas normarroquíes dudosas (Rif y Atlas Medio). Los ejemplares estudiados fueron atraídos por luces artificiales durante la noche, en diferentes ocasiones a lo largo de los meses de julio y agosto. Los rasgos morfológicos de los ejemplares ceutíes son similares a los de los ejemplares ibéricos examinados por lo que se confirma su identidad con N. (X.) raymondi raymondi (Mulsant & Godart, 1860).
A Pulmonary Lactobacillus murinus Strain Induces Th17 and RORγt+ Regulatory T Cells and Reduces Lung Inflammation in Tuberculosis
Authors: Bernard-Raichon Lucie , Colom André , Monard Sarah C , Namouchi Amine , Cescato Margaux , Garnier Hugo , Leon-Icaza Stephen A , Métais Arnaud , Dumas Alexia , Corral Dan , Ghebrendrias Natsinet , Guilloton Pauline , Vérollet Christel , Hudrisier Denis , Remot Aude , Langella Philippe , Thomas Muriel , Cougoule Céline , Neyrolles Olivier , Lugo-Villarino Geanncarlo 
Published: September 2021

Abstract
The lungs harbor multiple resident microbial communities, otherwise known as the microbiota. There is an emerging interest in deciphering whether the pulmonary microbiota modulate local immunity, and whether this knowledge could shed light on mechanisms operating in the response to respiratory pathogens. In this study, we investigate the capacity of a pulmonary Lactobacillus strain to modulate the lung T cell compartment and assess its prophylactic potential upon infection with Mycobacterium tuberculosis, the etiological agent of tuberculosis. In naive mice, we report that a Lactobacillus murinus (Lagilactobacillus murinus) strain (CNCM I-5314) increases the presence of lung Th17 cells and of a regulatory T cell (Treg) subset known as RORγt+ Tregs. In particular, intranasal but not intragastric administration of CNCM I-5314 increases the expansion of these lung leukocytes, suggesting a local rather than systemic effect. Resident Th17 and RORγt+ Tregs display an immunosuppressive phenotype that is accentuated by CNCM I-5314. Despite the well-known ability of M. tuberculosis to modulate lung immunity, the immunomodulatory effect by CNCM I-5314 is dominant, as Th17 and RORγt+ Tregs are still highly increased in the lung at 42-d postinfection. Importantly, CNCM I-5314 administration in M. tuberculosis–infected mice results in reduction of pulmonary inflammation, without increasing M. tuberculosis burden. Collectively, our findings provide evidence for an immunomodulatory capacity of CNCM I-5314 at steady state and in a model of chronic inflammation in which it can display a protective role, suggesting that L. murinus strains found in the lung may shape local T cells in mice and, perhaps, in humans.
Severity of Sepsis Determines the Degree of Impairment Observed in Circulatory and Tissue-Resident Memory CD8 T Cell Populations
Authors: Moioffer Steven J , Danahy Derek B , van de Wall Stephanie , Jensen Isaac J , Sjaastad Frances V , Anthony Scott M , Harty John T , Griffith Thomas S , Badovinac Vladimir P 
Published: September 2021

Abstract
Sepsis reduces the number and function of memory CD8 T cells within the host, contributing to the long-lasting state of immunoparalysis. Interestingly, the relative susceptibility of memory CD8 T cell subsets to quantitative/qualitative changes differ after cecal ligation and puncture (CLP)–induced sepsis. Compared with circulatory memory CD8 T cells (TCIRCM), moderate sepsis (0–10% mortality) does not result in numerical decline of CD8 tissue-resident memory T cells (TRM), which retain their “sensing and alarm” IFN-γ–mediated effector function. To interrogate this biologically important dichotomy, vaccinia virus–immune C57BL/6 (B6) mice containing CD8 TCIRCM and skin TRM underwent moderate or severe (∼50% mortality) sepsis. Severe sepsis led to increased morbidity and mortality characterized by increased inflammation compared with moderate CLP or sham controls. Severe CLP mice also displayed increased vascular permeability in the ears. Interestingly, skin CD103+ CD8 TRM, detected by i.v. exclusion or two-photon microscopy, underwent apoptosis and subsequent numerical loss following severe sepsis, which was not observed in mice that experienced moderate CLP or sham surgeries. Consequently, severe septic mice showed diminished CD8 T cell–mediated protection to localized skin reinfection. Finally, the relationship between severity of sepsis and demise in circulatory versus tissue-embedded memory CD8 T cell populations was confirmed by examining tumor-infiltrating and nonspecific CD8 T cells in B16 melanoma tumors. Thus, sepsis can differentially affect the presence and function of Ag-specific CD8 T cells that reside inside tissues/tumors depending on the severity of the insult, a notion with direct relevance to sepsis survivors and their ability to mount protective memory CD8 T cell–dependent responses to localized Ag re-encounter.
Murine Inducible Nitric Oxide Synthase Expression Is Essential for Antifungal Defenses in Kidneys during Disseminated Cryptococcus deneoformans Infection
Authors: Goughenour Kristie D , Zhao Jessica , Xu Jintao , Zhao Ziyin P , Ganguly Anutosh , Freeman Christine M , Olszewski Michal A 
Published: September 2021

Abstract
Disseminated cryptococcosis has a nearly 70% mortality, mostly attributed to CNS infection, with lesser-known effects on other organs. Immune protection against Cryptococcus relies on Th1 immunity with M1 polarization, rendering macrophages fungicidal. The importance of M1-upregulated inducible NO synthase (iNOS) has been documented in pulmonary anticryptococcal defenses, whereas its role in disseminated cryptococcosis remains controversial. Here we examined the effect of iNOS deletion in disseminated (i.v.) C. deneoformans 52D infection, comparing wild-type (C57BL/6J) and iNOS−/− mice. iNOS−/− mice had significantly reduced survival and nearly 100-fold increase of the kidney fungal burden, without increases in the lungs, spleen, or brain. Histology revealed extensive lesions and almost complete destruction of the kidney cortical area with a loss of kidney function. The lack of fungal control was not due to a failure to recruit immune cells because iNOS−/− mice had increased kidney leukocytes. iNOS−/− mice also showed no defect in T cell polarization. We conclude that iNOS is critically required for local anticryptococcal defenses in the kidneys, whereas it appears to be dispensable in other organs during disseminated infection. This study exemplifies a unique phenotype of local immune defenses in the kidneys and the organ-specific importance of a single fungicidal pathway.
The Association Between Running Injuries and Training Parameters: A Systematic Review
Authors: Fredette Anny , Roy Jean-Sébastien , Perreault Kadija , Dupuis Frédérique , Napier Christopher , Esculier Jean-Francois 
Published: September 2021

Objective
To synthesize the current evidence on the incidence of running-related injuries (RRIs) and their association with training parameters (distance, duration, frequency, intensity), as well as recent changes in training parameters.

Data Sources
Searches were conducted in MEDLINE/Ovid, CINAHL, Embase, and SPORTDiscus from their inception through July 7, 2020.

Study Selection
Included articles had to report prospective data on RRIs and training parameters or any changes in parameters and be published in English or French. Two reviewers independently screened the titles, abstracts, and full texts.

Data Extraction
Two independent raters performed data extraction and quality assessment using QualSyst, a quality appraisal tool.

Data Synthesis
A total of 36 articles that involved 23 047 runners were included. Overall, 6043 runners (26.2%) sustained an RRI (incidence range = 8.8%–91.3%). The incidence of RRI was 14.9% in novice runners (range = 9.4%–94.9%), 26.1% in recreational runners (range = 17.9%–79.3%), and 62.6% in competitive runners (range = 52.6%–91.3%). The 3 most frequently injured body parts were the knee (25.8%), foot/ankle (24.4%), and lower leg (24.4%). Overall, evidence about the association between weekly running distance, duration, frequency, intensity, or specific changes in training parameters and the onset of RRIs was conflicting.

Conclusions
Despite high rates of RRIs, current evidence does not consistently link RRIs with specific training parameters or recent changes in training parameters. Therefore, caution should be taken when recommending optimal parameters or progressions. Given the multifactorial nature of RRIs, future studies also need to consider the interactions between training parameters as well as psychosocial, hormonal, lifestyle, and recovery outcomes to better understand the onset of RRIs.
Changes in eating and residence customs: case study of the native community of Mayuriaga, Loreto
Authors: Bourguet Jose Yvan Vargas , Chunga Alex Alonso Pinzón , Sánchez Raúl Eleazar Arias 
Published: September 2021

This research work aims to provide a referential framework of assessment in the context of social damage from the anthropological interpretation of the inhabitants of the native community of Mayuriaga, due to the loss of quality of life, five years after the crude oil spill by part of the Petroperú company occurred in the North Peruvian Pipeline in the Morona River area in the Morona district, Daten de Marañón province, Loreto department, Peru; affecting the lifestyle of the surrounding ethnic communities. This extra-patrimonial damage is expressed and evidenced in eating habits; and residence, in the customs of the traditional use of water, recreation, social stability (tranquility), in the economy, in medicine and in the physical spaces of socialization and social incorporation. Likewise, to know these characteristics, the ethnographic method and on-site visits to the locality that were the subject of our research were used. Finally, we indicate that a quantity of relevant information was collected on the perceptions and changes in the lifestyles of the inhabitants, this thanks to the techniques of interview and observation.

El presente trabajo investigación pretende brindar un marco referencial de valoración en el contexto del daño social desde la interpretación antropológica de los pobladores de la comunidad nativa de Mayuriaga, por la pérdida de la calidad de vida, a cinco años después del derrame de petróleo crudo por parte de la empresa Petroperú ocurrido en el Oleoducto Norperuano en la zona del río Morona en el distrito de Morona, provincia del Daten de Marañón, departamento Loreto, Perú; afectando el estilo de vida de las comunidades étnicas aledañas. Este daño extrapatrimonial se expresa y evidencia en los hábitos alimenticios; y de residencia, en las costumbres del uso tradicional del agua, la recreación, la estabilidad social (tranquilidad), en la economía, en la medicina y en los espacios físicos de socialización e incorporación social. Asimismo, para conocer estas características, fue empleado el método etnográfico y las visitas in situ a la localidad motivo de nuestra pesquisa. Finalmente, indicamos que, fue recolectada cantidad de información relevante sobre las percepciones y cambios en los estilos de vida de los pobladores, esto gracias a las técnicas de la entrevista y la observación
Dynamics of the level of calprotectin in patients with rheumatoid arthritis during rituximab biosimilar (Acellbia “Biocad”) therapy
Authors: Avdeeva A. S. , Cherkasova M. V. , Nasonov E. L. 
Published: September 2021

Objective.To study the relationship between the level of calprotectin (CP) and RA activity, the level of acute phase reactants, proinflammatory cytokines, chemokines and growth factors, to assess its dynamics during rituximab (RTM) biosimilar therapy.Material and methods.20 patients with RA were examined. All patients received 2 intravenous infusions of RTM (Acellbia®) at a dose of 600 mg with an interval of 2 weeks against the background of methotrexate therapy. The level of CP in blood serum was measured by ELISA.Results.Before starting DAS28 (5.6 [4.9–6.8]), SDAI (27.17 [23.08–39.9]) and CDAI (26.6 [22.25–37.0]) corresponded to the high disease activity. A decrease in disease activity was noted after 12 and 24 weeks of therapy: the DAS28 value was 4.28 [3.24–4.75] and 4.14 [3.11–4.66], respectively (p<0.05). Before the start of therapy, patients with RA had a higher CP level compared with healthy donors 9.68 (4.5–21.5) and 2.39 (1.52–4.45) μg/ml, respectively (p<0.05). Against the background of RTM therapy, there was a decrease in the CP level 12 weeks after the first infusion of the drug in the group as a whole by 26.5% from the initial level, among patients with moderate/no effect of therapy – by 32.7% from the initial level.Conclusion.The CP level significantly decreases during therapy and can be used to monitor the effectiveness of therapy. The predictive value of this laboratory parameter requires further study.
Insulin resistance and type 2 diabetes mellitus risk factors in systemic lupus erythematosus
Authors: Kondratyeva L. V. , Popkova T. V. , Cherkasova M. V. , Lila A. M. , Nasonov E. L. 
Published: September 2021

Objective. To clarify the frequency of insulin resistance (IR) in patients with systemic lupus erythematosus (SLE), traditional and associated with rheumatic disease risk factors for its development, to assess the possibility of using the Finnish Type 2 Diabetes Risk Assessment Score (FINDRISC) questionnaire to detect IR.Material and methods. The cross-sectional study included 49 patients with SLE (46 women, 3 men) without diabetes mellitus and hyperglycemia, observed at the V.A. Nasonova Research Institute of Rheumatology in 2019–2020. The median age of the patients was 40 [33; 48] years, the duration of the disease was 3.0 [0.7; 8.0] years. Glucocorticoids (GC) were received by 41 (84%) patients, hydroxychloroquine – by 38 (78%), immunosuppressive drugs – by 10 (20%), biological agents – by 5 (10%). The glucose and fasting immunoreactive insulin levels were examined, and the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) index was calculated in all patients. HOMA-IR value ≥2.77 corresponded to IR. Traditional risk factors for type 2 diabetes and the risk of its development in the next 10 years in patients with SLE were assessed using the Russian version of the FINDRISC questionnaire.Results. The median HOMA-IR level in SLE patients was 1.7 [1.2; 2.5]. IR was detected in 10 (20%) of 49 patients with SLE. Patients with and without IR were comparable in terms of sex, age, duration and activity of SLE, therapy, and type 2 diabetes traditional risk factors. BMI, WC and insulin levels were higher in patients with IR. HOMA-IR correlated with body mass index (BMI) (r=0.6; p<0.001), waist circumference (WC) (r=0.5; p<0.001), risk categories for developing type 2 diabetes according to FINDRISС (r=0.3; p=0.03), SLEDAI-2K index (r=–0.4; p<0.01), C3 complement levels in serum (r=0.3; p=0.04) and the duration of GC therapy (r=0.3; p=0.03).Conclusion. IR was diagnosed in 20% of SLE patients without a history of diabetes and with normal fasting glucose in venous blood. The lower SLE activity, the longer GC intake in patient, the higher the HOMA-IR index was detected in him. However, the IR appearance was reliably associated only with an increasing BMI and WC. The use of the FINDRISC questionnaire, which allows to stratify respondents in the general population by the risk of developing type 2 diabetes mellitus, did not help to identify SLE patients with IR.
Denkyemmireku: A Usable Past for A New African State
Authors: BOADI Kwasi 
Published: September 2021

In Ghana – The Autobiography of Kwame Nkrumah (1971), Nkrumah recounts the deliberations within the United Gold Coast Convention on J. B. Danquah’s proposal for adopting the Akan art motif Funtummireku Denkyemmireku (Denkyemmireku, for short), the proverbial two-headed crocodile, as emblem for the emerging nation of Ghana. Dismissing it as a “hideous monstrosity” that symbolizes selfishness, it was never adopted. Yet, the art motif, a kind of jeremiad that says pity that poor crocodile, whose two heads cannot stop fighting over food, even though they share one stomach, is a recognition of the dialectic of nature as one of unity in diversity, the very essence of the hallowed African monistic thesis of matter. This paper posits that Denkyemmireku embodies a potent philosophical and ideological symbol capable of serving as a usable past for a much-needed reconstruction of a more legitimate African state.

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1 Some aspects of this article have been previously published in the Journal of Black Studies by the author. See, Kwasi Boadi, “The Ontology of Kwame Nkrumah’s Consciencism and the Democratic Theory and Practice in Africa – A Diopian Perspective.” Journal of Black Studies, Volume 30, Number 4 / March 2000, 475–501.