bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantifying the impact of the COVID-19 pandemic on cancer screenings and diagnoses
Authors: Carroll Rachel , Duea Stephanie , Prentice Christopher 
Published: August 2021

Abstract
COVID-19 impacted hospital systems across the globe. Focus shifted to responding to increased healthcare demand while mitigating COVID-19 spread on their campuses. Mitigation efforts limited medical professional-patient interactions, including patient access to preventive cancer screenings. This study tested five hypotheses: H1: Cancer screenings significantly decreased during North Carolina’s (NC) Stay-At-Home (SAH) orders; H2: Cancer diagnoses significantly decreased during NC’s SAH orders; H3: Cancer screenings significantly increased after the end of NC’s SAH orders; H4: Cancer diagnoses significantly increased after the end of NC’s SAH orders; and H5: Advanced cancer diagnoses significantly increased after the end of NC’s stay-at-home orders. Time series regression analysis was employed to quantify trends. Results suggested strong support of H1 and H3, moderate support of H4, mixed support of H5, and no support of H2. Implications of employing robust statistical methods to quantify trends in screenings or diagnoses during periods of health system disruption are discussed.
Cinnamomum cassia essential oil and (E)-cinnamaldehyde as control agents of anthracnose on common bean seeds
Authors: Pereira Fernanda Aparecida Castro , Silva Geraldo Humberto , de Souza Elaine Aparecida , de Oliveira Denilson Ferreira , Macedo Willian Rodrigues , Silva Adriene Aparecida 
Published: August 2021

Abstract
Among the fungi that cause damage to the common bean and are disseminated by the seeds, Colletotrichum lindemuthianum (Sacc. e Magn.) Briosi e Cavara stands out. This fungus causes anthracnose in common bean ( Phaseolus vulgaris L.). Use of natural compounds is a viable and safer option than chemicals to manage this disease. Essential oils have shown antifungal potential against phytopathogenic fungi. According to the results of the in vitro test, we observed complete inhibition of the growth of C. lindemuthianum with the use of cassia cinnamon essential oil ( Cinnamomum cassia ) (EO) and its major component ( E )-Cinnamaldehyde, presenting MIC of 125 µg/mL, while the commercial fungicide presented MIC of 30.6 µg/mL. And in vivo , where seeds naturally infected with C. lindemuthianum were treated with the EO and the substance in a solution with commercial soybean oil, we observed that the treatments did not affect germination and initial seed vigor. In addition, the seed treatment with solutions formulated from EO and ( E )-cinnamaldehyde was efficient for reducing the incidence of anthracnose over the days evaluated, as well as for the commercial fungicide used (methyl thiophanate). This is the first study to demonstrate the efficacy of C. cassia oil and (E)-cinnamaldehyde in the control of C. lindemuthianum through the treatment of common bean seeds.
Analytical Study of Early Kick Detection and Well Control Considerations for Casing while Drilling Technology
Authors: Azab M 
Published: August 2021

Abstract
Recently, casing while drilling (CwD) technology has been employed to reduce drilling time and expenses. These intelligent drilling technique improved wellbore stability, fracture gradient, and formation damage while reducing exposure time but when a well control issue arises, the differences in wellbore geometries and related volumes compared to regular conventional drilling procedures necessitate a distinct strategy. In this paper, the essential well control parameters were provided for casing while drilling operations, presents simplified method that has been developed to evaluate the maximum kick tolerance (KT) for both conventional and casing while drilling techniques using a mathematical derivation, the narrow annular clearance, in contrast to drilling with a conventional drill string would impair kick detection and handling operations. Furthermore, the large disparity in kick tolerances should be carefully evaluated in order to avoid lost circulation/kick cycles as well as examine and evaluate technical approaches to early kick detection (EKD) studying how they relate to safety, efficiency, and reliability in a variety of common casing while drilling operations. According to preliminary findings, by utilizing casing while drilling technology and compared to identical well was drilled conventionally using drill pipe, the annulus pressure loss (APL) is average 3 times of the conventional drilling technique. Furthermore, kick tolerance is reduced by 50% and maximum allowable well shut-in time reduced by 65% necessitating early kick detection.
Large broad-leaved canopy of banana (Musa nana Lour.) induces dramatically high spatial–temporal variability of throughfall
Authors: Zhang Wanjun , Zhu Xiai , Chen Chunfeng , Zeng Huanhuan , Jiang Xiaojin , Wu Junen , Zou Xin , Yang Bin , Liu Wenjie 
Published: August 2021

Abstract
Throughfall (TF) is an important water input of rainfall redistribution into floor, and its spatial–temporal variability under some species' canopies has been documented to evaluate effect on splash erosion. However, the understanding of TF variability under large broad-leaved canopy remains insufficient. In this study, the spatial heterogeneity, temporal stability and drop size of TF were quantified using variogram fitting, normalised ranking and filter paper staining, respectively, under banana (Musa nana Lour.) canopy comprising long and wide leaves. Results indicated TF pattern showed strong spatial correlation at a range of 3–5 m. High spatial variability of TF was found, which was affected by rainfall event size and was accompanied by great canopy disturbance. TF plots revealed high time variability, which was mainly controlled by unstable banana canopy structure. TF drop size from leaf dripping points varied in 3–10 mm and showed significant differences (p &lt; 0.05) among five kinds of leaf shapes, implying that concave and broken banana leaves were involved in the variability of TF drop size. Overall, results demonstrate the spatial–temporal variability of TF is dramatically induced by banana canopy with broad leaves, which may result in non-uniform soil water content and splash erosion under the canopy.
Numerical and experimental study on solute transport through physical aquifer model
Authors: Mayank Muskan , Sharma Pramod Kumar 
Published: August 2021

Abstract
Environmental concerns have drawn much research interest in solute transport through porous media. Thus, contaminants of groundwater permeate through pores in the ground, and adsorption attenuates the pollution concentration as the pollutants adhere to the solid surface. Mathematical models based on certain simplifying assumptions have been used to predict solute transport. The transport of solutes in porous media is governed by a partial differential equation known as the advection-dispersion equation. In this study, a two-dimensional numerical model has been developed for solute transport through porous media. Results of spatial moments have been predicted and analysed in the presence of both constant and time-dependent dispersion coefficients. Afterward, a numerical model is used to simulate experimentally observed breakthrough curves for both conservative and non-conservative solutes. Thus, transport parameters are estimated through numerical simulation of observed breakthrough curves. Finally, this model gives the best simulation of observed breakthrough curves, and it can also be used in the field scale.
Insight into the comparison of thermally and Fe(II) activated persulfate on sludge dewaterability and disintegration
Authors: Guo Shaodong , Zhou Long , Huang Yuxin , Huang Xinghu 
Published: August 2021

Abstract
The effects of thermally and Fe(II) activated potassium persulfate (PPS) on sludge dewatering performance were compared systematically. Sludge dewaterability was monitored by measuring capillary suction time (CST) and sludge specific resistance to filtration (SRF), and the degradation effect was characterized by chemical oxygen demand (COD), total organic carbon (TOC), ammonia nitrogen (NH4+-N) and extracellular polymeric substances (EPS). The change of extracellular polymer substance (EPS) including soluble, loosely bound and tightly bound EPS (S-EPS, LB-EPS and TB-EPS) with time and PPS dosage was monitored to discuss the oxidation efficiency of thermally and Fe(II) activated PPS. Sludge supernatant was analyzed by three-dimensional fluorescence excitation–emission spectra (3D-EEM) to confirm the protein transformation. The result showed that sludge dewaterability in terms of CST and SRF were enhanced with increasing PPS dosage and condition time of two activated methods. While Fe(II) activated PPS could reduce sludge CST and SRF to preferred values at low PPS dosage and short condition time. Meanwhile, sludge degradation effect was also more obvious. Mechanically, sludge TB-EPS in proteins and polysaccharides converted to SB-EPS was faster with Fe(II) activated PPS. In addition, thermally activated PPS tended to oxidize the protein in the supernatant first.
Whole cell microalgal-cyanobacterial array biosensor for monitoring Cd, Cr and Zn in aquatic systems
Authors: Rathnayake I. V. N. , Munagamage Thilini , Pathirathne A. , Megharaj Mallavarapu 
Published: August 2021

Abstract
Bioavailable content of metals in aquatic systems has become critical in assessing the toxic effect of metals accumulating in the environment. Considering the need for rapid measurements, an optical microalgal-cyanobacterial array biosensor was developed using two strains of microalgae, Mesotaenium sp. and a strain of cyanobacteria Synechococcus sp. to detect Cd2+, Cr6+ and Zn2+ in aquatic systems. Microalgal and cyanobacterial cells were immobilized in a 96-well microplate using sol-gel method using silica. Optimum operational conditions for the biosensor array such as exposure time, storage stability, pH, and multiple metal effect were tested. A 10 min exposure time yielded optimum fluorescence values. Metal toxicity increased with decreasing pH, resulting in low relative fluorescence (%) and decreased with increasing pH, resulting in higher relative fluorescence (%). The optimum storage time for biosensor strains were 4 weeks for microalgal cultures and 8 weeks for cyanobacterial culture, at 4 °C storage temperature. The metal mixtures showed less effect on the inhibition of relative fluorescence (%) of microalgal/cyanobacterial cultures, displaying an antagonistic behavior among the metals tested. As a single unit, this photosynthetic array biosensor will be a valuable tool in detecting multi-metals in aquatic systems.
Multiscale Biology of Cardiovascular Risk in Psoriasis: Protocol for a Case-Control Study
Authors: Kaiser Hannah , Kvist-Hansen Amanda , Becker Christine , Wang Xing , McCauley Benjamin D , Krakauer Martin , Gørtz Peter Michael , Henningsen Kristoffer Mads Aaris , Zachariae Claus , Skov Lone , Hansen Peter Riis 
Published: August 2021

Background
Patients with psoriasis have increased risk of cardiovascular disease (CVD) independent of traditional risk factors. The molecular mechanisms underlying the psoriasis-CVD connection are not fully understood. Advances in high-throughput molecular profiling technologies and computational analysis techniques offer new opportunities to improve the understanding of disease connections.

Objective
We aim to characterize the complexity of cardiovascular risk in patients with psoriasis by integrating deep phenotypic data with systems biology techniques to perform comprehensive multiomic analyses and construct network models of the two interacting diseases.

Methods
The study aims to include 120 adult patients with psoriasis (60 with prior atherosclerotic CVD and 60 without CVD). Half of the patients are already receiving systemic antipsoriatic treatment. All patients complete a questionnaire, and a medical interview is conducted to collect medical history and information on, for example, socioeconomics, mental health, diet, and physical exercise. Participants are examined clinically with assessment of the Psoriasis Area and Severity Index and undergo imaging by transthoracic echocardiography, 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT), and carotid artery ultrasonography. Skin swabs are collected for analysis of microbiome metagenomics; skin biopsies and blood samples are collected for transcriptomic profiling by RNA sequencing; skin biopsies are collected for immunohistochemistry; plasma samples are collected for analyses of proteomics, lipidomics, and metabolomics; blood samples are collected for high-dimensional mass cytometry; and feces samples are collected for gut microbiome metagenomics. Bioinformatics and systems biology techniques are utilized to analyze the multiomic data and to integrate data into a network model of CVD in patients with psoriasis.

Results
Recruitment was completed in September 2020. Preliminary results of 18F-FDG-PET/CT data have recently been published, where vascular inflammation was reduced in the ascending aorta (P=.046) and aortic arch (P=.04) in patients treated with statins and was positively associated with inflammation in the visceral adipose tissue (P<.001), subcutaneous adipose tissue (P=.007), pericardial adipose tissue (P<.001), spleen (P=.001), and bone marrow (P<.001).

Conclusions
This systems biology approach with integration of multiomics and clinical data in patients with psoriasis with or without CVD is likely to provide novel insights into the biological mechanisms underlying these diseases and their interplay that can impact future treatment.

International Registered Report Identifier (IRRID)
DERR1-10.2196/28669
Ultrasound-Assisted Extraction of Phenolics and Antioxidants from Propolis for Stabilization of Sunflower Oil
Authors: Golmahi Zeinab , Elhamirad Amir Hossein 
Published: August 2021

Propolis is one of the byproducts of honey bees; it contains many phenolic compounds which are some of the most important natural antioxidants. The present study examined the antioxidant activity of propolis and its role in the stability of sunflower oil as a natural antioxidant in the form of Box–Behnken design. The extraction process was performed using an ultrasonic bath method with two factors in three levels which included 18 assays by the response surface methods. The investigated variables included the concentration of the extract (min: 30 and max: 1000 ppm), the extraction time (min: 10 and max: 30 minutes), and temperature (min: 37.5 and max: 50°C). After analysis of the data in optimal conditions, the concentration of propolis ethanol extract, extraction temperature, and extraction time was determined as 997.5 ppm, 34.6°C, and 30 min, respectively. In this condition, the total phenolic compounds and the free-radical scavenging properties were reported as 253.1mgGAE/100gDW and 85.9%, respectively. The result of the evaluation of the oxidative stability of the optimized sample oil showed reduced peroxide and thiobarbituric acid index compared to the control sample and synthetic antioxidants (BHT); also, the oil stability improved significantly over time.
La sátira gráfica de Calpurnio y El Roto sobre la digitalización social: un análisis crítico desde la perspectiva de las competencias digitales
Authors: Gómez-Hernández José-Antonio , Fernández-Rincón Antonio-Raúl 
Published: August 2021

A digitalização massiva e acelerada implica uma grande transformação da nossa vida privada e da nossa atividade social, com repercussões pessoais, políticas e económicas. Este fenômeno de digitalização da vida deve ser compreendido pelos cidadãos e, portanto, requer competência informacional e pensamento crítico. Uma das formas de promover a reflexão crítica sobre a sociedade digital é a sátira gráfica, e por isso o objetivo deste trabalho é expor como os dois principais autores espanhóis têm lidado com esta questão: Calpurnio e El Roto. A metodologia consistiu na procura e identificação de vinhetas, classificando-as quanto às suas críticas ao abuso das tecnologias de informação e suas consequências, tomando como referência para a análise principalmente o Quadro Europeu de Competência Digital. Concluímos que os principais riscos que aparecem na sátira gráfica são a incapacidade de organizar as informações, a conexão excessiva que leva à dependência digital, a desinformação e a vulnerabilidade às notícias falsas, que facilitam a manipulação política e econômica, a transferência irresponsável de dados e seu uso indevido, perda de privacidade ou deterioração das relações interpessoais. A sátira à digitalização não pretende ser uma tecnofobia, mas sim um pensamento crítico necessário do humor, prevenindo os riscos pela adoção irrefletida da tecnologia sem competição pelo seu uso consciente, pensativo e intencional.
Palavras-chave: sátira gráfica. O quebrado. Calpurnio. competência digital. competência informativa, riscos digitais
Desafios na Gestão da Informação na Era Digital no contexto da Ciência da Informação
Authors: Paletta Francisco Carlos 
Published: August 2021

Estudo exploratório com objetivo de analisar, no contexto da Ciência da Informação, como as organizações lidam com as complexidades do mercado de trabalho global de profissionais da informação. Apresenta reflexões sobre a forma como a transformação digital tem influenciado as estratégias de inovação das organizações e a sua arquitetura de sistemas de informação. Visa também estudar as complexidades da sociedade da rede, cujas novas configurações de produção constituem objeto de investigação para profissionais de vários campos, especialmente os que atuam na gestão e organização da informação considerando as suas diferentes dimensões: científica, tecnológica, industrial, marketing, estratégica e social.
Palavras-chave: Gestão da Informação. Era Digital. Complexidade do Mercado de Trabalho Global. Transformação Digital. Inovação. Ciência da Informação.
Sorte ou Técnica? Um Estudo sobre o Desempenho do Mercado de Ações à Luz de Diferentes Técnicas de Previsão
Authors: Sameer El Khatib Ahmed 
Published: August 2021

Objetivo: examinar o desempenho preditivo de modelos lineares, não-lineares, de inteligência artificial, domínio de frequência e híbridos para encontrar um modelo apropriado de previsão do retorno das ações de mercados desenvolvidos, emergentes e de fronteira. Metodologia: foram considerados os retornos diários do mercado de ações de índices selecionados de mercados desenvolvidos, emergentes e de fronteira de 24 países para o período de 2000–2019, para avaliar o desempenho preditivo de cinco modelos existentes. Principais Resultados: os resultados indicaram que nenhum dos cinco modelos poderia ser aplicado uniformemente a todos os mercados. No entanto, os modelos lineares e não lineares tradicionais superaram a inteligência artificial e os modelos no domínio da frequência ao fornecer previsões mais precisas. Contribuições acadêmicas e práticas: este estudo é útil principalmente para investidores internacionais e investidores institucionais estrangeiros que desejam minimizar riscos e diversificar suas carteiras, com o objetivo de maximizar lucros.
EFEKTIVITAS MODEL PEMBELAJARAN EXAMPLE NON EXAMPLE BERBANTUAN MEDIA PAPAN CACAH GORI TERHADAP PRESTASIBELAJAR MATEMATIKA DITINJAU DARI AKTIVITAS BELAJAR PESERTA DIDIK
Authors: Nur Aizah Ratri , Dwi Wahyuningsih Eleonora , Shaefur Rokhman Mohammad 
Published: August 2021

Prestasi belajar matematika peserta didik kelas VII SMP Negeri 7 Pemalang sebagian masih ada yang belum mencapai nilai KKM. Berkaitan hal ini perlu adanya variasi dalam pembelajaran yang dapat melibatkan peserta didik untuk lebih aktif. Upaya yang dapat digunakan adalah penerapan model pembelajaran Example Non Example. Kemudian untuk membantu peserta didik dalam memahami materi, model pembelajaran dibantu berupa media papan cacah gori. Tujuan penelitian ini adalah untuk mengetahui : (1) adanya perbedaan antara prestasi belajar matematika peserta didik yang diajar menggunakan model pembelajaran Example Non Exampleberbantuan media papan cacah gori dengan peserta didik yang diajar menggunakan model pembelajaran ekspositori ditinjau dari aktivitas belajar, (2) apakah prestasi belajar matematika peserta didik yang diajar menggunakan model pembelajaran Example Non Exampleberbantuan media papan cacah gori lebih baik daripada prestasi belajar matematika peserta didik yang diajar menggunakan model pembelajaran ekspositori ditinjau dari aktivitas belajar tinggi, (3) apakah prestasi belajar matematika peserta didik yang diajar menggunakan model pembelajaran Example Non Exampleberbantuan media papan cacah gori tidak lebih baik daripada prestasi belajar matematika peserta didik yang diajar menggunakan model pembelajaran ekspositori ditinjau dari aktivitas belajar rendah.
Populasi dalam penelitian ini adalah peserta didik kelas VII SMP Negeri 7 Pemalang Tahun Pelajaran 2016/2017 yang terdiri atas 300 peserta didik. Sampel terdiri dari 190 peserta didik, dimana teknik pengambilan sampel menggunakan teknik cluster random sampling. Sampel yang diambil sebanyak dua kelas sebagai kelas eksperimen, dua kelas sebagai kelas kontrol, dan satu kelas sebagai kelas uji coba. Teknik pengumpulan data yang digunakan adalah dokumentasi, angket dan tes. Teknik analisis data menggunakan RAK (Rancangan Acak Kelompok) dan uji t pihak kanan dan kiridengan taraf signifikansi 5%.
Hasil penelitian menunjukan bahwa : (1) ada perbedaan prestasi belajar matematika yang diajar menggunakan model pembelajaran example non example berbantuan media papan cacah gori dengan model ekspositori ditinjau dari aktivitas, (2)prestasi belajar matematika yang diajar menggunakan model pembelajaran example non exampleberbantuan media papan cacah gorilebih baik daripada yang diajar menggunakan model ekspositori ditinjau dari aktivitas tinggi, (3) prestasi belajar matematika yang diajar menggunakan model pembelajaran example non exampleberbantuan media papan cacah gori lebih baik daripada yang diajar menggunakan model ekspositori ditinjau dari aktivitas rendah.
Peningkatan Kemampuan Pemahaman Konsep Matematika Siswa Dengan Model Pembelajaran Improve Berbantuan Kertas Origami Pada Materi Perpangkatan Dan Bentuk Akar Kelas IX.E Smp Negeri 7 Pemalang Tahun Pelajaran 2019/2020 Semester Gasal
Authors: Nursidik Nursidik 
Published: August 2021

Masalah yang dihadapi siswa antara lain kurangnya pemahaman konsep matematika siswa terhadap materi Perpangkatan dan bentuk akar, kurangnya minat siswa terhadap pembelajaran, siswa cenderung pasif dalam pembelajarandan Pandangan siswa yang menilai bahwa matematika sulit dipahami.
Tujuan penelitian ini untuk meningkatkan pemahaman konsep matematika siswa. Indikator keberhasilan penelitian ini yaitu adanya pencapaian rata-rata persentase pemahaman konsep berdasarkan nilai tes akhir siklus meningkat dibandingkan sebelumnya dengan rata-rata minimal menunjuk kriteria tinggi dan 70% siswa dikelas mencapai KKM ≥ 75, dan sebagai pendukung yaitu pencapaian keterlaksanaan pembelajaran matematika minimal menunjuk kriteria tinggi.
Hasil penelitian menunjukkan peningkatan persentase pencapaian tes pemahaman konsep siklus 1 ke siklus 2 berturut-turut adalah 67,3% (sedang) menjadi 75,3% (tinggi), peningkatan persentase siswa yang tuntas KKM dari siklus 1 ke siklus 2 berturut-turut adalah 51,3% siswa menjadi 74,35% siswa. Persentase keterlaksanaan pembelajaran guru siklus 1 ke siklus 2 yaitu 66,7% (sedang) menjadi 88,9% (tinggi) dan persentase aktivitas siswa siklus 1 ke siklus 2 yaitu 55,7% (sedang) menjadi 83,3% (tinggi).
Penerapan model pembelajaran improve berbantuan kertas origami pada pelajaran matematika dapat dijadikan sebagai variasi sekaligus alternatif dalam memberikan pembelajaran yang menunjang dalam pencapaian pemahaman konsep matematika siswa,karena didalamnya sangat memotivasi siswa untuk mencari pengalaman sendiri dalam menemukan sebuah konsep.