bluuebunny/crossref_metadata_2025_split huggingface dataset:
AS PINTURAS RUPESTRES DA TRADIÇÃO NORDESTE NA REGIÃO DO SERIDÓ, RN, NO CONTEXTO DA ARTE RUPESTRE BRASILEIRA
Authors: Pessis Anne-Marie , Martin Gabriela 
Published: December 2021

Este artigo é uma reflexão sobre as pinturas rupestres da tradição Nordeste na região arqueológica do Seridó, que precisam ainda de estudos pormenorizados do seu vasto acervo arqueológico. Se pode afirmar que, paralelamente às pinturas do Parque Nacional Serra da Capivara, no estado do Piauí, os conjuntos rupestres do Seridó representam o maior acervo gráfico do nordeste do Brasil. Esta afirmativa não está apenas baseada na quantia dos sítios e dos registros, mas na riqueza imagética que os mesmos representam. Retratam as numerosas atividades da vida cotidiana e cerimonial dos povos que as fizeram, além da manifestação da cultural material, imaterial e técnica do pensamento abstrato indígena na pré-história brasileira. THE RUPESTRAL PAINTINGS OF THE NORTHEAST TRADITION IN THE SERIDÓ REGION, RN, IN THE CONTEXT OF BRAZILIAN RUPESTRY ART ABSTRACTThis article is a reflection on the cave paintings of the Northeast tradition in the archaeological region of Seridó, which still need detailed studies of their vast archaeological collection. It can be said that, in parallel to the paintings in the Serra da Capivara National Park in the state of Piauí, the rock paintings ensembles of Seridó represent the largest graphic heritage in the northeast of Brazil. This statement is not just based on the number of sites and records, but on the wealth of images that they represent. They portray the numerous activities of the daily and ceremonial life of the peoples who did them, as well as the manifestation of the material, immaterial and technical culture of indigenous abstract thought in Brazilian prehistory.Keyword: Rock Art; Seridó; Northeast tradition.
A UTILIZAÇÃO DE ADORNOS CORPORAIS NA PRÉ- HISTÓRIA DA ÁREA ARQUEOLÓGICA DO SERIDÓ – RN
Authors: Cisneiros Daniela , Nogueira Nathalia , Santos Camila 
Published: December 2021

Os adornos corporais estão entre as primeiras manifestações simbólicas produzidas pelo Homo sapiens e evidenciadas em dados arqueológicos. São fontes portadoras de informações sobre tecnologia e identidade. A região do Seridó apresenta em seu acervo arqueológico elementos materiais e gráficos que atestam o uso desses adornos na pré-história. O presente artigo tem por objetivo apresentar as tipologias, usos e funções dos adornos nos contextos funerários e rupestres do Seridó Potiguar. Os dados de 11 sítios analisados permitiram inferir que os grupos que habitaram a região em períodos pré-históricos utilizavam-se de adornos de diversas tipologias (adornos de cabeça, colares e pingentes); confeccionados com diferentes matérias-primas e utilizados em distintos contextos (rituais funerários, caça, sexo e violência). THE USE OF PERSONAL ORNAMENTS IN PREHISTORY OF THE ARCHAEOLOGICAL AREA OF SERIDÓ - RN ABSTRACTThe personal ornaments are among the first symbolic manifestations produced by Homo sapiens sapiens and manifested in archaeological data. They are sources of information about technology and identity. The Seridó region has material and graphic elements in its archaeological collection that attest to the use of ornaments in prehistory. This paper aimsto present the types, uses, and functions of ornaments in the funerary and rock art of Seridó Potiguar. The data from 11 analyzed sites allowed us to infer that the groups that inhabited the region in prehistoric periods used ornaments of different types (head ornaments, necklaces, and pendants) made with different raw materials and used in different contexts (funerary rituals, hunting, sex, and violence).Keywords: Personal ornaments; Seridó Prehistory; Rock Art
A Dual-Directional Flow Control Device for Cyclic Steam Stimulation Applications
Authors: Zhu Da 
Published: December 2021

Summary
Cyclic steam stimulation (CSS) is one the most effective thermal recovery methods. It is widely used as the primary thermal recovery method to recover heavy oil fields in the Middle East, the Asia-Pacific region, and North and South America. In this paper, a novel dual-directional flow control device (FCD) will be introduced. This FCD technology can allocate accurate steam outflow into the reservoir formation and improve steam quality during the steam injection period and can mitigate steam breakthrough from the neighboring wells during the production period. In the first section, we give a brief introduction on CSS and the main issues encountered in the field operation. A multidirectional flow control nozzle specifically designed for CSS application will be presented. Design philosophy in thermodynamics and hydrodynamics of the nozzle will be discussed in detail. Field performance results, computational fluid dynamics (CFD), and flow loop testing data will be shown to evaluate the performance of the technology. The application of the technology in steam-assisted thermal applications will be introduced. Well-known issues such as erosion and scaling on the FCD tools will be studied in the end.
Comprehensive Analysis and Assessment of the Role of Major Bioactive Compounds Isolated from Justicia Adhatoda Leaves as Potent Antimycobacterial Agents
Authors: Mishra Smita , Mehra Varsha 
Published: December 2021

Abstract
Tuberculosis (TB) continues to be one of the world's leading causes of death by the infectious pathogen Mycobacterium tuberculosis, which infects one-third of the global population. The emergence of the COVID-19 pandemic made its spread rapid and the treatment task more daunting. With the havoc of infectious disease expansion, traditional medicines have triggered tremendous interest worldwide. However, less availability of scientific evidence still hinders its practical use. In the present study, we evaluated the potential of the traditional medicinal plant, Justicia adhatoda, which has been used to treat respiratory ailments since ancient times. We have successfully isolated and characterized several bioactive compounds viz- Vasicoline, Vasicolinone, Adhatodine, Adhavasine, Aniflorine, and Vasicinone from J. adhatoda plant leaves, including Vasicine as the principal compound, and showed their anti-tubercular activity on nutrient-starved Mycobacterium smegmatis and Mycobacterium bovis. The study also directs their in-vitro and ex-vivo antimycobacterial potential on THP1 macrophages with internalized Mycobacterium. Our study is one of its first kind, where we assessed the synergistic antimycobacterial effect of the isolated compounds with the first-line drug Isoniazid (INH). Their potential role in promoting phagolysosome fusion and apoptosis of M. bovis infected THP1 macrophages is further evaluated.
Evaluation of a Pharmacy Supported e-Cigarette Smoking Cessation Intervention in North West England
Authors: Price Alan D. , Coffey Margaret , Houston Lawrence , Cook Penny A. 
Published: December 2021

Abstract
Background: Cigarette smoking cessation has been described as the world’s most important public health intervention. Electronic cigarettes are a relatively new tool for assisting smoking cessation but there is a lack of data on their efficacy. This article reports on a pharmacy supported e-cigarette smoking cessation intervention undertaken in a metropolitan area in the north of England.Methods: Longitudinal mixed-methods evaluation incorporating analysis of secondary data, interviews with service users, and interviews with service providers at 3-month and 12-month follow-up, with an additional text message survey of service users at 12-month follow-up. Results: The four-week follow-up data suggest that for every twenty people given an e-cigarette, six quit smoking tobacco and three people cut their cigarette intake by more than five cigarettes per day. Long-term follow-up results were positive but only a small number of participants were still engaged with the study at 12 months. Service users and providers spoke positively about the combination of e-cigarettes and pharmacy support.Conclusions: E-cigarette distribution combined with pharmacy support appears to be an agreeable and effective intervention for smoking cessation, but further data are needed on long-term quit rates and health effects.
Water Vapour Sorption and Moisture Transport in and Across Fibre Direction of Wood
Authors: Murr Alexander 
Published: December 2021

Abstract
Water vapour sorption experiments are frequently used to characterise the absorption and desorption of water in wood during transient conditions in relative humidity. When interpreting such experiments, it is still unclear to what extend the resulting time-dependent change of sample mass (i.e. sorption kinetics) is influenced by moisture transport, sorption and sorption related processes. To evaluate the impact of water vapour diffusion under such transient conditions, this study investigates the sorption kinetics of small wood samples with different lengths of transport pathways in and across fibre direction. For this purpose, water vapour sorption experiments on Norway spruce ( Picea abies ) samples were performed under identical climatic conditions at ambient air pressure and ambient standard temperature. The results showed that sample thickness has an impact on the sorption kinetics along the whole tested range of relative humidity. Differences between the sorption kinetics for samples in and across fibre direction were considerable at low relative humidity, indicating the relevance of water vapour diffusion through the lumen-pit-ray system. In contrast at high relative humidity, differences between the sorption kinetics for samples in and across fibre direction started to disappear while the impact of sample thickness was still considerable. Therefore, it seems as if an additional or modified process that depends on the number of sorption sites becomes relevant at an increased moisture content of wood. This process, as well as the increasing uptake and release of water across fibre direction, should be further investigated to gain a better understanding of the absorption and desorption of water in wood.
Effect of Early Protective Lung Ventilation on Mortality and Hemodynamics in Patients With Acute Myocardial Infarction Complicated With Cardiogenic Shock and Pulmonary Edema Undergoing Emergency Interventional Therapy
Authors: Yang Hao , Han Chuyi , Guo Xiaoling , Wang Hongliang , Wu Yanda , Cong Hongliang 
Published: December 2021

Abstract
Background: To investigate the effect of early protective lung ventilation (EPLV) on mortality and hemodynamic parameters in patients with acute myocardial infarction complicated with cardiogenic shock (CS) and pulmonary edema undergoing emergency percutaneous coronary intervention (PCI).Methods: From January 2015 to June 2017, patients with acute myocardial infarction complicated with CS and pulmonary edema were admitted to the Tianjin chest Hospital. Based on the use of a mechanical ventilator, patients were divided into the EPLV and Non-invasive ventilation (NIV) groups. Hemodynamic indexes and in-hospital mortality of patients between the two groups was analyzed.Results: The EPLV group consisted of 51 patients and the NIV group consisted of 38 patients. The difference in mortality rates was statistically significant between the EPLV and NIV groups (P=0.01). Central venous pressure, pulmonary artery pressure, and pulmonary capillary wedge pressure after emergency PCI in the EPLV group were lower compared to patients in the NIV group ((P<0.05). Man arterial pressure in patients in the EPLV group was higher compared to NIV patients (P<0.05). Logistic regression analysis showed that EPLV did not increase the risk of mortality (P=0.37, OR=2.16, 95% CI (0.31, 9.52)).Conclusion: EPLV resulted in lower mortality and improved hemodynamic function in patients with acute myocardial infarction complicated with CS and pulmonary edema undergoing emergency PCI.
A Novel Cooperative Network Using Down-link Non-orthogonal Multiple Access Scheme
Authors: Mohsan Syed Agha Hassnain , Hamood Moqbel Ali Mohammed , Shah Syed Muhammad Tayyab , Mazinani Alireza 
Published: December 2021

Abstract
A novel downlink cooperative non-orthogonal multiple access (DC-NOMA) scheme is proposed in this paper to achieve higher performance in the spectral efficiency compared to the classical NOMA schemes. The communication system consists of one base station and two users (e.g., strong user and weak user). In down link phase, the base station transmits a superimposed signal to both users, and in the cooperative phase, the weak user sends its decoded message to the strong user. The main idea is how the weak user can help the strong user to improve the performance of both users. This occurs by enabling the weak user to perform a cooperative transmission with the strong user during the cooperative phase. The outage probability, outage throughput, and diversity order are derived and analyzed. Numerical results are provided to show that the spectral efficiency gain achieved through our proposed scheme is better than the conventional cooperative NOMA schemes.
Dental Anomaly Detection Using Intraoral Photos Via Deep Learning
Authors: Ragodos Ronilo , Wang Tong , Padilla Carmencita , Hecht Jacqueline , Poletta Fernando , Orioli Iêda , Buxó Carmen , Butali Azeez , Valencia-Ramirez Consuelo , Muñeton Claudia Restrepo , Wehby George , Weinberg Seth , Marazita Mary , Uribe Lina Moreno , Howe Brian 
Published: December 2021

Abstract
Children with orofacial clefting (OFC) present with a wide range of dental anomalies. Identifying these anomalies is vital to understand their etiology and to discern the complex phenotypic spectrum of OFC. Such anomalies are currently identified using intra-oral exams by dentists, a costly and time-consuming process. We claim that automating the process of anomaly detection using deep neural networks (DNNs) could increase efficiency and provide reliable anomaly detection while potentially increasing the speed of research discovery. This study characterizes the use of` DNNs to identify dental anomalies by training a DNN model using intraoral photographs from the largest international cohort to date of children with nonsyndromic OFC and controls (OFC1). In this project, the intraoral images were submitted to a Convolutional Neural Network (CNN) model to perform multi-label multi-class classification of 10 dental anomalies. The network predicts whether an individual exhibits any of the 10 anomalies and is able to do so significantly faster than a human rater. For every anomaly except mammalons, F1 scores suggest that our model performs competitively at anomaly detection when compared to a dentist with 8 years of clinical experience. In addition, we use saliency maps to provide a post-hoc interpretation for our model’s predictions. This enables dentists to examine and verify our model’s predictions.
A Pan-Cancer Analysis of the KIF Family Gene and their Association with Prognosis, Tumor Microenvironment, and Therapeutic Targets
Authors: Xu Qitong , Guo Yiming , Xu Feng , Zhang Xu , Cai Mengyuan , Yang Chuang , Huang Yuzhou , Zhang Mian , Wei Jifu , Ding Qiang 
Published: December 2021

Abstract
Background: Recently, studies have shown that kinesins(KIF) play an important role in the occurrence and development of many tumors. However, there is no complete understanding of the role of KIF family in Pan cancer, and its role in the immunity and tumor microenvironment (TME) is unclear.Methods: Based on TCGA database and integrated several R packages, we explored the relationship between the expression of KIF genes and patient survival, immune subtypes, TME, tumor stem cell correlation, and drug sensitivity in cancer.Results: We use nine highly expressed KIF genes(KIF2C, KIF4A, KIF7, KIF11, KIF14, KIF18A, KIF18B, KIF20A, KIF20B) to represent whole KIF family. The change in KIF gene expression was significantly related to overall survival. The nine KIFs' high expression is accompanied by the up-regulation of C1 immune subtype, which is related to cell proliferation and interruption of immune process. Further, KIF gene expression showed significant correlation and cancer cell stemness characteristics. Top25 relevant KIF-drug pairs were displayed according to their P values. We further discussed KIF family influence in Mesothelioma(MESO) and Sarcoma(SARC). The CIBERSORT results manifested that increased level of infiltration of B cells naive, Mast cells resting and NK cells activated could be used as a protective factor to promote survival.Conclusions: Our study supplemented a complete map of the effect of KIF family in Pan cancer. We suggested that KIF family may be a potential target for cancer therapy.
Studies on Mitigation of Printing Cost, Volatile Organic Compounds Emission and Sustainability in Printing Industries by Using Water-based Inks
Authors: Sharma Bhavna , Singh Sauraj , Pandey Arun , Dutt Dharm , Kulshreshtha Anurag 
Published: December 2021

Abstract
Organic solvents have been frequently and excessively used in the printing process for a long time. The use of organic solvents in solvent-based ink is responsible for fire hazards, volatile organic compounds emission, and high manufacturing cost during printing. The present study aimed at replacing solvent based ink with water-based ink for reducing the volatile organic compounds emissions and carbon footprints in gravure printing without affecting overall printing quality. The PET film was printed with a water-based ink laser engraved cylinder having reduced cell depth and it resulted in the transfer of a low volume of inks on printing substrate. The cost of printing one kg of polyester film with water-based ink was reduced by US$ 1.95 compared to solvent-based ink. The volatile organic compounds emissions for water-based ink were measured at 2478 ppm against 3373 ppm for solvent-based ink. The water-based ink reduced the carbon footprint by 3.04 kg, which was equivalent to CO2 during printing of one kg polyester film used for making flexible pouches compared to solvent-based ink. The outcome of this study may be the benchmark to authorities for green manufacturing systems in gravure printing applications for the betterment of the environment and humanity.
Genome-Wide Identification of Carbapenem-Resistant Gram- Negative Bacterial (CR-GNB) Isolates Retrieved From Hospitalized Patients in Bihar, India
Authors: Kumari Namrata , Kumar Mukesh , Katiyar Amit , Kumar Abhay , Priya Pallavi , Kumar Bablu , Biswas Nihar Ranjan , Kaur Punit 
Published: December 2021

Abstract
Carbapenemase-producing clinical isolates are becoming more common over the world, posing a severe public health danger, particularly in developing nations like India. Carbapenem-resistant Gram-negative bacterial (CR-GNB) infection has become a fast-expending global threat with limited antibiotic choice and significant mortality. The aim of this study was to highlight the carbapenem-resistance among clinical isolates of hospital admitted patients in Bihar, India. A cross-sectional study was conducted with 101 clinical isolates of E. coli, K. pneumoniae, A. baumannii, and P. aeruginosa. All GNB isolates were tested for their antimicrobial susceptibility using double disc synergy test / modified hodge test (DDST/MHT) and subsequently confirmed carbapenemase-producing isolates were evaluated for carbapenem-resistance genes using whole-genome sequencing (genotypically) method. The overall percentage of carbapenem-resistance among GNB was (17/101) 16.83%. The AMR analysis demonstrates a significantly high prevalence of blaCTX−M followed by blaSHV, blaTEM, blaOXA and blaNDM β-lactams carbapenem-resistance genes among clinical isolates of GNB. Co-occurrence of carbapenemase-encoding genes with blaNDM was found in 70.6% of carbapenemase-producing isolates. Our study highlights the mechanism of carbapenem-resistance to curb the overwhelming threat posed by emergence of drug-resistance in India.
Correlation Between Extent of Lacrimal Gland Prolapse and Clinical Features of Thyroid- Associated Ophthalmopathy: A Retrospective Observational Study
Authors: Gao Yang , Chang Qinglin , Li Yang , Zhang Hanqiao , Hou Zhijia , Zhang Zheng , Li Zheng , Li Dongmei 
Published: December 2021

Abstract
Background: Studies on the factors related to lacrimal gland prolapse (LGP) in patients with thyroid-associated ophthalmopathy (TAO) are limited. This study aimed to assess the ability of abnormal location of the lacrimal gland on magnetic resonance images to predict disease activity in patients with TAO.Methods: Thirty-six patients (72 orbits) with inactive TAO (43 orbits, Clinical Activity Score [CAS] <3) or active TAO (29 orbits, CAS ≥3) were investigated retrospectively. All patients underwent ophthalmic evaluation and orbital magnetic resonance imaging. The severity of LGP and proptosis and the extraocular muscle (EOM) volume were measured. LGP and related factors were assessed by correlational and linear regression analyses. The value of LGP for discriminating the activity of TAO was evaluated by receiver-operating characteristic curve analysis.Results: The mean LGP was significantly higher in the active TAO group than in the inactive TAO group (P<0.001). There were significant positive correlations between LGP severity and the CAS (r=0.51, P<0.001), proptosis (r=0.72, P<0.001), and EOM volume (superior rectus [r=0.49, P<0.001], inferior rectus [r=0.47, P<0.001], lateral rectus [r=0.59, P<0.001], medial rectus [r=0.62, P<0.001], superior oblique [r=0.48, P<0.001], and all EOMs [r=0.59, P<0.001]). Receiver-operating characteristic curve analysis revealed an LGP of 13.65 mm (area under the curve, 0.824; sensitivity, 79.3%; specificity, 81.4%) to be the cut-off value that differentiated active and inactive TAO.Conclusions: LGP measurements obtained from orbital magnetic resonance images were positively correlated with CAS, proptosis and EOM volum. The extent of LGP appears to be a good indicator of disease activity in patients with TAO.
Phthalates, non-phthalates, polychlorinated biphenyls and phenyl phosphates in atmospheric suspended particulate matter of Dhahran City, Saudi Arabia: Levels and seasonal variation
Authors: Rushdi Ahmed I , Simoneit Bernd R. T. , Lijotra Luis , Bazeyad Abdulqader Y. , Dumenden Ramil , El-Mubarak Aarif H. , Qurban Mohammed A. , Al-Mutlaq Khalid F. 
Published: December 2021

Abstract
This work describes the seasonal variations, levels, and possible health effects of groups of persistent organic pollutants (POPs) as phthalates (Ps), non-phthalates (NPs), polychlorinated biphenyls (PCBs), and phenyl phosphates (PhePhs) in ambient total suspended particles (TSP) from the city of Dhahran, Saudi Arabia. The mass concentrations of TSP ranged from 88±32 µg m−3 in winter to 350±320 µg m−3 in summer. The total concentrations of these compounds varied from 337±266 ng m−3 in summer to 469±403 ng m−3 in winter. The major compounds were Ps (235±199 ng m−3 in summer to 389±335 ng m−3 in winter), PCBs (30.7±19.3 ng m−3 in autumn to 65.6±61.2 ng m−3 in summer), NPs (4.9±2.3 ng m−3 in summer to 11.9±12.5 ng m−3 in winter), and PhePhs (4.1±4.0 ng m−3 in spring to 13.3±3.2 ng m−3 in summer). The proportional fractions of these POPs relative to natural biogenic sources and petroleum-related emissions were extremely high ranging from 17% in winter to 47% in autumn. Significant correlations were found among these different POP groups and total concentrations, suggesting that they were from local sources. Principal component analysis indicated that Ps and NPs were from the same initial sources, and the PhePhs as well as PCBs were from different regional sources, where the latter were dependent on the TSP levels. In the long term, the elevated levels of these POPs in the TSP of these urban areas will affect human health by eventually developing a range of illnesses.