bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of individual and organisational variables on the perception of organisational values
Authors: Adamonienė Rūta , Litavniece Lienite , Ruibytė Laima , Viduolienė Evelina 
Published: July 2021

Abstract
A favourable organisational culture founded on the values of employees and organisation leaders must be created to achieve goals, innovate and maintain a well-functioning organisation. Knowing these values and how they are influenced by various factors, such as age, the length of service, and the nature of work, must help to change employee beliefs, norms and behaviour patterns in a way that helps to achieve greater organisational success and efficiency. The study sample size consisted of 172 employees of educational institutions and 242 employees from municipal organisations. Occupational features and occupational behaviour were evaluated using a set of organisational values (Glomseth et al., 2011). The current research aimed (1) to evaluate organisational values and feature dimensions with respect to the inter-institutional level, (2) to evaluate organisational values and feature dimensions and distinguish the most prevalent with respect to the subordination level, (3) to evaluate organisational values and feature dimensions with respect to individual variables (gender, age and the length of occupational experience). The results revealed that task effectiveness, time management and cooperation, employee-orientated behaviour were stronger in educational organisations than municipal. Authoritarian management, formality and restrictions were stronger in municipal rather than educational organisations. Compared to beliefs held by subordinates, superiors claimed that positive organisational values, such as effectiveness, cooperation, and employee-orientated behaviour, were more typical in both types of institutions. Formal communication and restrictions were more typical for employees rather than managers. Subordinates but not superiors tended to perceive and evaluate organisational values, features and behaviour differently depending on gender.
Methodology for multi-criteria assessment of working conditions as an object of qualimetry
Authors: Trishch Roman , Cherniak Olena , Kupriyanov Oleksandr , Luniachek Vadym , Tsykhanovska Iryna 
Published: July 2021

Abstract
The article considers several modern scientific papers substantiating the need for assessing workplace safety and focusing on methods applied for the quantitative assessment of working conditions. The analysis found unsolved problems in qualimetry, which could lead to the development of new practical and generally applicable methods to effectively assess working conditions. The analysis proved the relevance of the topic and helped to determine the aim of the article, i.e., the development of a methodology for the quantitative assessment of working conditions in industries, considering harmful production factors. An exponential distribution, which belongs to the theory of extreme statistics, was proposed for the transition of heterogeneous single indicators of harmful factors into a dimensionless scale. Affine transformations were used to combine dissimilar scales, making it possible to divide segments on dissimilar scales into equal proportions. The article proposes a step-by-step method for determining a complex indicator of working conditions in industries. The proposed methodology allows management decisions that minimise the deviation in actual values of harmful factors from the optimal ones. The developed technique was tested at one specific metallurgical production site.
Just “performance nonsense”?: How recipients process news photos of activists’ symbolic actions about climate change politics
Authors: Wozniak Antal 
Published: July 2021

Abstract
In this article, I investigate how recipients make sense of images that show symbolic actions by environmental activists during two recent United Nations Climate Change Conferences. Environmental advocacy groups are successful in creating visibility for their symbolic actions via news visuals, but little empirical evidence exists about how ordinary media recipients engage with this type of imagery. Can they understand the intended meaning of complex visual rhetoric used by environmental activists? I use think-aloud protocols to uncover the cognitive strategies which are used in processing these stylised visual claims. Results show that news photos rarely manage to communicate the intended meaning of symbolic actions. By systematically analysing various stages of visual frame processing, this study offers insights into specific configurations of the image-viewer relationship that cause high levels of ambiguity and prevent staged visual claims from being understood as intended. Yet I also find empirical evidence for a visual framing approach that works well and describe this recipe for effective communication via symbolic action photography.
SOSIALISASI PHBS DENGAN PEMBAGIAN PANCURAN AIR DAN SABUN CUCI TANGAN KEPADA WARGA RT.09 KELURAHAN LEMPAKE KOTA SAMARINDA
Authors: Siska Oktaviani  , Miftahul Jannah  
Published: July 2021

Hasil observasi pada salah satu RT di Kelurahan Lempake yaitu RT. 09 didapatkan informasi bahwa fasilitas untuk mencuci tangan masih jarang ditemui di tempat-tempat keramaian di RT tersebut, kemudian masih ada warga yang tidak memakai masker ketika berinteraksi dengan warga lain serta kurang sadarnya warga sekitar mengenai pola hidup bersih dan sehat. Pengabdian masyarakat ini bertujuan memberikan pengetahuan dan pemahaman mengenai PHBS dalam rangka pencegahan penyebaran Covid-19 kepada warga RT. 09 Kelurahan Lempake. Metode yang dilakukan pada sosialisasi ini melalui penyampaian materi mengenai protokol kesehatan dan PHBS dengan membagikan video edukasi cuci tangan melalui grup WhatsAppwarga serta pembagian pancuran air dan sabun cuci tangan. Kegiatan sosialisasi PHBS dengan pembagian pancuran air dan sabun cuci tangan kepada warga di lingkungan RT. 09 mendapat dukungan yang positif, baik dari ketua RT. 09 maupun warga sebagai salah satu bentuk kegiatan untuk mengedukasi warga bahwa dengan mencuci tangan dengan sabun dengan langkah-langkah yang benar maka warga sudah berpartisipasi dalam rangka memutus mata rantai penyebaran Covid-19.
Synthesis, Characterization, in silico and in vitro Studies of Transition Metal Complexes with Biologically Active Ligand as Antigout Agent Colchicine
Authors: Gaikwad Vaishali , Sabale Vaibhav , Khade Bhimrao 
Published: July 2021

Colchicine is essentially useful in the treatment of gout. In the present work Colchicine Complexes has been prepared with transition metals viz; Copper(II) [Cu(II)], Zinc (II) [Zn(II)], Cobalt (II) [Co(II)], Nickel (II) [Ni(II)] and those checked for molecular docking, it has been observed that Zn(II) and Ni(II) complex has revealed good binding energy than the parent ligand, the increased binding energy of colchicine metal complexes indicates that, the tubulin polymerization inhibitor tendency is enhanced, consequently antigout property is also increased. As transition metals have antimicrobial activity in themselves, complexes are also characterized for the antimicrobial activity which is enhanced for Cu(II) and Co(II) metals.
Evaluation of in vitro Antioxidant and Cytotoxic Effect of Methanol Extract from aerial parts of Myristica beddomei King ssp. ustulata W.J. de Wilde
Authors: Joy Neethu , Mohan Mahesh 
Published: July 2021

Plants are traditionally used for pharmacological activities because of its ability to produce bioactive compounds. Myristica beddomei King ssp. ustulata W.J. de Wilde is an ethnomedicinal plant and it is seen in South Western Ghats of Kerala, India. The present study assessed the phenolic content, flavonoid concentration, in vitro antioxidant and cytotoxic effect of different parts of Myristica beddomei King. The total phenolic contents in the extracts ranged from 96.29 (pericarp) to 314.47 (bark) mg g-1 gallic acid equivalent. The concentration of flavonoids in different plant part extracts ranged from 1.81 to 2.76 mg g-1 equivalent to quercetin. All the parts exhibited potential antioxidant activity with an IC50 value of 2.87 to 9.67 μg ml-1 when compared to the standard ascorbic acid with an IC50 value of 2 μg ml-1 in 1,1-diphenyl-2- picryl-hidrasil (DPPH) method. Bark showed highest activity in terms of DPPH radical scavenging (IC50 value of 2.87 µg ml-1), phosphomolybdenum test (2261.33 ± 1.65 mg g-1 trolox equivalent) and ferric ion reducing antioxidant power (FRAP) (113.1 ± 0.28 µmol Fe2+ µg-1) while pericarp showed low antioxidant activity. The in vitro screening results revealed that the seeds exhibited promising anticancer activity compared to PA1 (Ovarian Cancer) cells (50 % inhibition) were observed at a concentration 100.68 µg ml-1. In cytotoxicity test L929 (Fibroblast) cell line compared to the other parts pericarp, mace and seed needed higher concentration (>240 µg ml-1) for LC50 value. It is a promising plant for further development of antioxidant agent as it got high content of phenolic compounds and potential antioxidant and anticancer activity.
Development of bioanalytical standardization parameters of Alocasia indica tuber by HPTLC technique
Authors: Aneshwari Roman Kumar , SAHU ANIL KUMAR , Vyas Amber , JAIN VISHAL 
Published: July 2021

Alocasia indica is perennial herb growing widely and used as traditional medicine in India, China and Bangladesh. The divine herb has potent medicinal values for the treatment of different type of illnesses. The HPTLC techniques were used to separate active components from ethanolic extract of tuber part of A. indica. This examination was intended to designed a HPTLC fingerprint profile of crude extract of the plant in ethanol. A HPTLC method for the isolation of various active constituents in A. indica ethanolic extract have been developed and solvent system for quercetin the mobile phase used was toluene: ethyl acetate: formic acid (5:2:1) and for analysis of β-sitosterol the mobile phase used was chloroform: ethyl acetate: formic acid (6:4:1) . In the present investigation, HPTLC fingerprint of extract of dried tuber part of A. indica have been performed and the results demonstrated that important information for standardization. The HPTLC system for routine quality control of present species can be used for ethanolic extract and serve in qualitative, quantitative and was appropriate for standardization of the plant.
Fourier Transform Infrared and Chromatographic Fingerprint of Essential Oil from Pogostemon benghalensis (Burm. F.) Kuntze
Authors: Premakumari Pradeep Damodaran , Sarayu Manoj Gopal , Kumaraswamy Murugan 
Published: July 2021

The purpose of the present research work is to investigate the functional group and category of secondary metabolites present in the essential oil (Eo) from Pogostemon benghalensis using Fourier transform infrared (FTIR) spectrometry, HPTLC and GC-MS technique. FTIR measures the vibrations of bonds within the functional groups and yields a spectrum that can be considered as biochemical or metabolic fingerprint of the plant product. Using FTIR spectra, it is possible to find out the minor changes of primary and secondary metabolic characteristic functional groups which are responsible for their biological feature of the species. FTIR is a nondestructive, cost effective, user and eco-friendly tool. Pogostemon benghalensis, a wild relative of P. cablin, the highly utilized and adulterated medicinal herb by the native people for the extraction of essential oil Patchouli. The fresh leaves were subjected to hydro distillation for the extraction of the essential oils and were analyzed using the above techniques. The FTIR spectral lines have shown diverse unique peaks of functional groups. FTIR confirmed the volatile compounds and indicated by their functional groups of the essential oils such as C-H (Alkene), C-H (aromatic) and C=C. Similarly, the analysis proved the presence of alcohols, p-substituted alcohols or phenols, alkanes, alkynes, alkenes, aldehyde, ester, ether, aliphatic amines, carboxylic acids, aromatics, ketones, disulphide, alkyl halides, halogen, and nitro derivatives. The intensity and estimation of predominant volatiles were analysed by HPTLC, which showed 8 peaks with max Rf values ranged from 0.07 to 0.96. Further, the Eo was fractionated by with GC-MS technique and identified 41 volatile fractions in the oil. Thus, the obtained data provides the biochemical profiles with overlapping signals of a wide array of molecules that are present in the cells. So, the usage of essential oils in pharmacy, cosmetology and aromatherapy industries may be substantiated. Further advanced spectroscopic analysis is required to identify the structure and nature of active principles present in the Eo.
Validation of In-vitro Deposition of Emitted Dose Method for Simultaneous Estimation of Formoterol Fumarate and Glycopyrrolate in combined Dry Powder Inhaler Aerosol Pharmaceutical Dosage Form
Authors: Kotak Ravindra K , Pandya Chintan V , Pandya Aditee C 
Published: July 2021

Formoterol Fumarate and Glycopyrrolate Dry powder inhaler is combined aerosol dosage form. The label claim of this combined dosage form is 25 mcg of Glycopyrrolate and 6 mcg of Formoterol Fumarate per respicap. It is prescribed for treatment of Asthma and COPD. Formoterol Fumarate is anti asthmatic drug (Bronchodilator) and Glycopyrrolate is quaternary ammonium compounds which is Anticholinergic Drug. A bronchodilator is a substance that dilates the bronchi and bronchioles, decreasing resistance in the respiratory airway and increasing airflow to the lungs while Glycopyrrolate blocks muscarinic receptors thus inhibiting cholinergic transmission. Glycopyrrolate is also known as Glycopyrronium Bromide, an Anticholinergic agent. It is used to inhibit salivation and excessive secretions of the respiratory tract preoperatively; reversal of neuromuscular blockade; control of upper airway secretions; and part of treatment for peptic ulcer. The present study aimed to Validate HPLC method for determination of Deposition of emitted dose of Formoterol Fumarate and Glycopyrrolate Analytes. This study covers Precision, Linearity, Accuracy, Robustness, Ruggedness, stability of analytical solution and Specificity. The chromatographic method uses a reversed phase column Purosphere star RP 18e (125 mm × 4.6 mm x 5 μm). The mobile phase was prepared by mixing Buffer : Acetonitrile : Methanol (68 : 24 : 8 %v/v/v) at flow rate 1.0 ml per min with UV and PDA detector 215 nm, column oven adjusted to 25° C with injection volume 100 μL. The method showed a successful application for determination of Formoterol Fumarate and Glycopyrrolate in Dry powder inhaler pharmaceutical formulation.
Direct Stereoselective Method Development and Validation of Elagolix on Zwitterionic Chiral Stationary Phase by High-Pressure Liquid Chromatography
Authors: Choppari Thirupathi , Gunnam Srinivasu , Chennuru Lakshmi Narayana , Cherla Parameswara Murthy 
Published: July 2021

A specific, sensitive and accurate chiral technique has been developed for the quantification of elagolix enantiomer in a drug product. The present research work represents the development and validation of chromatographic technique for the separation of elagolix enantiomers on a chiral stationary phase (CSP) comprising a zwitterionic selector derived from cinchona alkaloid and sulfonic acid CHIRALPAK ZWIX (+) under isocratic condition containing 50mM Acetic acid and 25mM diethyl amine in water and methanol in the ratio of 02:98 v/v with 0.5 ml min-1 flow rate. Temperature of the column was monitored at 40°C with a resolving factor more than 3.2. The eluted compounds were monitored at 275 nm. The optimized method has high degree of selectivity with lower limiting values of detection and quantitation and were found to be 2.0 ng/ml and 7.5 ng/ml, respectively for the enantiomeric chiral impurity. The developed method was subjected for validation as per the ICH guidelines, produced good findings regarding specificity, accuracy, precision, robustness and linearity.
Production of value added Oyster mushrooms
Authors: Sailaja Bandhakavi , Radhika Batchu 
Published: July 2021

Mushrooms are ironic in nutrimental resources and have converted into one of the common foods in the previous twenty years globally. The types of edible mushrooms are button, milky and oyster mushrooms. The research aimed at value addition of Oyster mushrooms by rising on paddy substrate complemented with two concentrations of four different medicinal plants. The plant parts selected were flowers of Butea monosperma, leaves of Moringa olifera, bark of Cinnamonom zeylianicum, fruits of Corindraum sativum at 5% and 10% concentration. Different species of oyster mushrooms are available. In the present study Pleurotus florida was selected for value addition. Maximum mycelium running rate was detected in Cinnamon bark (5%) and paddy straw (95%) accompanied group and lowermost running rate of mycelium was observed in Moringa leaf (5%) and paddy straw (95%). The primordial arrival was fast with Cinnamon bark (5%) supplemented group and slowest in Moringa leaf (5%) supplemented group. The mushrooms grownup on Coriander fruit (5%) produced more but the growth was slow. Mushrooms supplemented with Butea flower (5%) exhibited slow growth and yield was next to coriander fruit supplemented mushrooms. The produced mushrooms were subjected to physical evaluation, preliminary phytochemical testing and also tested for estimation of total flavonoids, total phenols, total tannins and total cinnamaldehyde contents. Value addition of Oyster mushrooms was successful with cinnamon bark as cinnamaldehyde was noticed in the Cinnamon bark supplemented group, and also with Moringa leaves as flavonoids was observed in more concentration in Moringa leaf supplemented mushroom group.
Development and Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Dapagliflozin Propanediol and Metformin Hydrochloride in Tablet Dosage Form
Authors: Patel Nikita Shaileshbhai , Patel Bhavesh Hirabhai 
Published: July 2021

A rapid, precise, accurate, specific and simple stability indicating RP-HPLC method was developed for simultaneous estimation of Dapagliflozin Propanediol (DAPA) and Metformin Hydrochloride (MET) in its tablet dosage form. Method was performed on a column C8 Thermoquest, hypersil division of dimension 250 mm × 4.60 mm having particle size 5 micron. The mobile phase used in the method was 10 mM Ammonium Acetate buffer (pH- 4), Methanol and Acetonitrile in proportion of 30:65:05 respectively. The drug was subjected to acid and alkali hydrolysis, oxidation, photolysis and heat as stress conditions. The method was validated for specificity, linearity, range, precision, accuracy, robustness, LOD, LOQ and system suitability. The flow rate was maintained at 0.8 ml/ min and effluent was monitored at 227 nm. The retention time were observed 5.988 min and 4.661 min for DAPA and MET respectively. The standard curve was found linear over range of 60-140 μg/ml for DAPA and 300-700 μg/ml for MET with correlation coefficient of 0.9996 for DAPA and 0.9994 for MET. The limit of Detection (LOD) of this method was 1.121 μg/ml for DAPA and 6.162 μg/ml for MET. The limit of Quantitation (LOQ) of this method was 3.396 μg/ml for DAPA and 18.674 μg/ml for MET. The percentage recovery was found to be in the range of 98-102% at three different levels of a standard addition. The precision (repeatability, intra-day and inter-day) of the method was within the limit (RSD<2%). Degradation products produced because of stress studies did not interfere with the detection of DAPA and MET and the assay can thus be considered stability-indicating. Combination tablet was successfully analysed using the developed method.
Study on Acidity and Neutralizing Ability of Ions in the Chemical Composition of Rainwater
Authors: Ngan Han Thi , Xuan Co Hoang , Thi Thu Ha Pham , Manh Khai Nguyen 
Published: July 2021

The acidity in rainwater is mainly controlled by the presence of H2SO4, HNO3 in combination with the ability to neutralize cations in rainwater. pH is an important value in the evaluation of acidity in rainwater. The research used a series of rainwater quality monitoring data from 2005 to 2018 in Vietnam. The research showed that the average pH distribution at 23 stations ranged from 5.83 ± 0.62. The rains with pH <5.6 appear in all years at the research stations. Considering the ability of acid neutralizing to various ions shows that Ca2+ is the main contributor to acid neutralization processes in rainwater, followed by Mg2 +, NH4+, and K+. While Ca2+ always play the highest acid neutralizing role at all stations; Depending on each station, Mg2+ and NH4+ ions play a role in neutralizing acidity in rainwater. The research also shows a match between the trend of H+ concentration and the tendency of cations to contribute to acid neutralization in rainwater.
Antagonic Activity of Endophytic Bacteria Isolated from Man Trau Grass on Stem Rot Disease Of Pitaya (Hylocereus Undatus)
Authors: Trung Do Quang , Thu Hang Nguyen Thi , Van Dinh Mai , Ngoc Pham Bich Bích , Hang Tran Thi , Anh Luu The , Tien Phi Quyet 
Published: July 2021

Endophytic bacteria reside in the intercellular spaces in different plant tissues without causing damage. This study aimed to select endophytic bacterial strains from Man Trau grass (Eleusine indica) that are able to inbibit the fungus A. alternata causing stem rot disease on pitaya. The result showed that one fungal isolate was pathogenic and caused stem rot disease on dragonfruit. The analysis results based on morphological characteristics and ITS region sequence indicated that the isolated fungal strain is 100% identical to A. alternata. In addition, a total of 16 endophytic bacterial strains were isolated from Man Trau grass samples in Binh Thuan and screened for antifungal activity. Ten bacterial strains with antagonistic activity against A. alternata causing stem rot disease on pitaya were detected. Among those, strain MT47 showed the strongest antifungal activity with an efficiency of 36.67%. Moreover, the result also presented that the antagonistic strain MT47 pocesses the ability of biofilm formation significantly higher than the control. The results suggest that these endophytic bacteria can be used in biocontrol of the stem rot disease on pitaya.
Thoracic intramedullary neurosarcoidosis with thoracic disc herniation: Diagnostic importance of intramedullary contrast enhancement
Authors: Beiriger Justin , Abou-Al-Shaar Hussam , Deng Hansen , Mathkour Mansour , Okonkwo David O. 
Published: July 2021

Background:
Thoracic intramedullary neurosarcoidosis is an uncommon but serious manifestation of spinal cord disease. Its concomitant occurrence with thoracic disc herniation can mislead the physician into attributing neurologic and radiographic findings in the spinal cord to disc pathology rather than inflammatory disorder. Here, we present such a rare case of concomitant thoracic disc and spinal neurosarcoidosis.

Case Description:
A 37-year-old male presented with progressive right lower extremity weakness and numbness. Magnetic resonance imaging (MRI) of the thoracic spinal cord revealed a T6-T7 paracentral disc eccentric to the right with T2 signal change extending from T2 to T10 level. This prompted acquiring a contrasted MRI that also depicted intramedullary enhancement around the T6-T7 disc bulge. Computed tomography scan of the chest showed mediastinal lymphadenopathy concerning for sarcoidosis. Lymph node biopsy confirmed the diagnosis of sarcoidosis, and high-dose steroid treatment was initiated. The patient had significant symptomatic improvement with steroids with full neurological recovery and improvement of his symptoms.

Conclusion:
While stenosis from thoracic disc disease could potentially suggest a mechanical etiology for the patient’s symptoms, attention must be paid to the imaging findings as well as the degree and extent of cord signal change and intramedullary contrast enhancement. Appropriate and timely diagnosis is essential to avoid unnecessary invasive procedures.