bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geology of minerals of the Tevlinsko-Russinskoe deposit
Authors: Almukhametova E M , Valeev A I , Gabdrakhmanov N Kh 
Published: April 2021

Abstract
The territory of the Tevlinsko-Russinskoe field is characterized by instability of the thermodynamic equilibrium of the geological environment, due to the existence of permafrost. The article considers the geological section of the region, its oil and gas content, analyzed the geological and physical information. The main technological solutions of the project document of the Tevlinsko-Russinskoe field are considered. Oil and gas content within the Urengoysky oil and gas region is established in a wide stratigraphic range. Tectonic screens, the presence of which is confirmed by the history of the field, complicate almost all deposits.
The efficiency of using a combined solar plant for the heat and humidity treatment of air
Authors: Aliyarova Lola Abdijabborovna , Uzakov Gulom Norboevich , Toshmamatov Bobir Mansurovich 
Published: April 2021

Abstract
The authors of this work have proposed a combined solar heating unit for the heat and humidity treatment of greenhouse air supplies. The object of research is a combined solar collector for the simultaneous heating of water and air. The heat and humidity treatment of supply air is an energy-intensive technological process that requires a very large consumption of thermal energy and water resources. For the operation of such a system, electric heating installations are often used; however, these systems are not always available and economical. In this paper, to reduce the consumption of traditional energy for the heat treatment of the air supply, a combined solar collector is proposed, and the results of an experimental study of the operating modes of the installation in the conditions of the city of Karshi are presented. It has been developed combined solar collector, the temperature of the heat carriers at the outlet in the heating mode “water + air” reached up to 48 °C (air) and up to 60 °C (water), which are acceptable for air treatment systems of heat and humidity in greenhouses. As a result of the experimental studies, the high energy efficiency of the combined solar collector in the “water + air” heating mode is shown. It has been established that the efficiency of the installation is in the range of 0.45 - 0.69.
Impact factory assessment on the air on the Pekhorka river basin
Authors: Novikov A V , Shiryaeva M A , Sumarukova O V , Lagutina N V , Barsukova M V 
Published: April 2021

Abstract
The background ecological situation on Pekhorka river of the Balashikha district is determined by its location in the eastern part of the Moscow agglomeration. Most of the neighboring industrial centers are located to the west of it, from the side of the prevailing winds. Enterprises harm the air state during construction works. The vast majority of the enterprises are concentrated on the territory of Balashikha. The article discusses an example of calculating air pollution from the enterprise influencing the environmental pollution on the river Pekhorka basin. Air samples were taken and data on emissions of substances into the atmosphere were obtained. The calculation of the impact of the enterprise on atmosphere pollution was carried out with a specialized program. As a result, calculation of the dispersion of pollutants concentrations were carried out, the schematic map of the concentrations of substances nitrogen dioxide and sulfur dioxide was created and measurs for the state of atmospheric air were suggested. Studies had shown that substances’ emissions slightly exceed the MPC and or did not exceed the MPC at all. However, it was necessary to carry out the regular atmosphere state monitoring to prevent damage to the environment.
Electricity metering in power supply systems with grid-connected solar power plants
Authors: Leshtayev O V , Stushkina N A , Zaginaylov V I 
Published: April 2021

Abstract
The article discusses the experience of using an induction meter of electrical energy in power supply systems with a network solar power plant connected in parallel to the centralized network. Amendments to Federal Law No. 35-FZ “On the Electricity Industry” of December 27, 2019, which determine the relevance of the construction and operation of grid solar power plants in Russia, have been studied. The block diagram of an experimental solar power plant (SPP) is presented. An experimental network solar power plant has been developed and tested, which makes it possible to assess the possibility of using this type of power plant in rural areas of the central Chernozem region, in a private courtyard. The calculation of the characteristics and the selection of brands of the main components used in the installation of the station, including an induction meter of electric energy, were made. The authors analyzed the consumption of electrical energy from a centralized electrical network without using a solar power plant and during its operation according to the readings of an electric meter. On the basis of the analysis carried out, conclusions were drawn about the reduction of electricity consumption from the centralized network during the operation of a network solar power plant. The operating modes of the electricity meter generated by the solar power plant, the consumption of electricity from the centralized network and the load of the consumer of electrical energy are described mathematically. The relationship between the direction of the current flowing through the counter, the magnetic fluxes induced on the counter disk and the direction of rotation of the disk is described on the basis of mathematical relationships. The authors draw conclusions about the possibility of using induction meters of electrical energy in parallel operation of solar power plants with a centralized network as devices for offsetting consumed and supplied electricity to the network.
Concerning the issue of resource assessment for solar energy utilization systems in the climatic conditions of the Russian Federation
Authors: Kurasov I S , Shchukina T V , Chudinov D M , Kononova M S , Mershchiev A A 
Published: April 2021

Abstract
The article deals with the distribution of the energy potential of solar radiation in the territory of the Russian Federation. The spatio-temporal regularities are revealed, which make it possible to assess the resource provision of engineering systems in a given renewable energy source. Graphical distributions of solar radiation for the northern latitudes of the Russian Federation, including the energy irradiance of vertical orientation surfaces by cardinal directions, are constructed. Equations are obtained for the possibilities of solar radiation depending on the considered month and latitude of the area. An amendment has been introduced that takes into account the decrease in the radiation intensity with average cloud cover for the regions. Revealed the territorial-temporal variability of the possibility of solar radiation, which makes it possible to assess the prospects of using or another system of utilization of radiation.
Role of the coal industry in regional sustainability of Krasnoyarsk Region
Authors: Savin O I , Makarchuk I Y , Savina E V , Panchenko V Y , Stupina A A , Petrov M A 
Published: April 2021

Abstract
This study is an attempt to analyze the prospects for the sustainable development of the coal industry in the Krasnoyarsk Region of Russia. The authors examined several important milestones in the formation of the industry and revealed some major issues, which hinder the development of the coal industry in Krasnoyarsk Region. This paper also evaluates the current state of the coal industry and discusses the plans for its further development from an economic and environmental point of view.
Modeling of sea currents and the spread of an oil slick in the Labrador Sea area
Authors: Martyn I , Petrov Y , Stepanov S , Sidorenko A 
Published: April 2021

Abstract
The article discusses the modeling of an oil spill in the Labrador Sea region using the Cardinal software package. The capabilities of the software package are shown. The use of a rectangular and curvilinear grid is presented, and the calculation of currents and spread of an oil slick is carried out under the condition of topographic irregularities of the sea bottom, the field of currents and wind conditions. As a result of the work, maps of the current field and sea level were obtained. The parameters of the oil spill were calculated, including the volume of dispersed and evaporated oil. And in conclusion, the transformation of an oil spill in the center of the sea for 5 days is shown.
Assessment and prospects of biogas use
Authors: Razinkov M I , Zhukova A A , Jovanovich S , Sorokin D E , Saidmurodova M A , Abramov V L , Novikova O V , Afanasyev Valentin Ya 
Published: April 2021

Abstract
This article reveals the relevance of the use and development of an alternative source of heat and power supply, which is biogas. The potential of such a clean energy source is very great. The demand of countries for biogas is different, but it is constantly increasing every year. It opens up a platform for a variety of services that depend on economic and political priorities. Biogas can provide energy and heat as well as clean cooking fuels to get rid of traditional energy sources. Biogas production solves the problem of growing volumes of organic waste, which contributes to the reduction of global greenhouse gas emissions.
Feeling Fit for Function: Haptic Touch and Aesthetic Experience
Authors: Roberts Tom 
Published: April 2021

Abstract
Traditionally, the sense of touch—alongside the senses of taste and smell—has been excluded from the aesthetic domain. These proximal modalities are thought to deliver only sensory pleasures, not the complex, world-directed perceptual states that characterize aesthetic experience. In this paper, I argue that this tradition fails to recognize the perceptual possibilities of haptic touch, which allows us to experience properties of the objects with which we make bodily contact, including their weight, shape, solidity, elasticity, and smoothness. These features, moreover, may be indicative of how well-suited an object is for its function, and in feeling them we can thus feel the positive aesthetic quality of functional beauty.
Use, Safety Assessment, and Implementation of Two Point-of-Care Tests for COVID-19 Testing
Authors: Hahn Megan , Olsen Aaron , Stokes Kindra , Fowler Randal C , Gu Rui , Semple-Lytch Shellanne , DeVito Andrea , Kurpiel Philip , Hughes Scott , Rakeman Jennifer L 
Published: April 2021

Abstract

Objectives
The Abbot ID NOW COVID-19 assay and Quidel Sofia 2 SARS Antigen FIA are point-of-care assays that offer rapid testing for severe acute respiratory syndrome coronavirus 2 viral RNA and nucleocapsid protein, respectively. Given the utility of these devices in the field, we investigated the feasibility and safety of using the ID NOW and Sofia assays in the public health response to the coronavirus disease 2019 pandemic and in future public health emergencies.

Methods
A combination of utilization and contamination testing in addition to a review of instrument workflows was conducted.

Results
Utilization testing demonstrated that both tests are intuitive, associated with high user test success (85%) in our study, and could be implemented by staff after minimal training. Contamination tests revealed potential biosafety concerns due to the open design of the ID NOW instrument and the transfer mechanisms with the Sofia. When comparing the workflow of the ID NOW and the Sofia, we found that the ID NOW was more user-friendly and that the transfer technology reduces the chance of contamination.

Conclusions
The ID NOW, Sofia, and other emerging point-of-care tests should be used only after careful consideration of testing workflow, biosafety risk mitigations, and appropriate staff training.
Albuminuria Intensifies the Link Between Urinary Sodium Excretion and Central Pulse Pressure in the General Population: The Wakuya Study
Authors: Tagawa Kaname , Tsuru Yusuke , Yokoi Katsumi , Aonuma Takanori , Hashimoto Junichiro 
Published: April 2021

Abstract

BACKGROUND
Central pulse pressure (cPP) is responsible for the hemodynamics of vital organs, and monitoring this parameter is important for cardiovascular disease (CVD) prevention. Excess sodium intake and (micro)albuminuria (a manifestation of renal microvascular damage) are known to be strong predictors of CVD. We sought to investigate the cross-sectional relationships among dietary sodium intake, albuminuria, and cPP in a general population cohort.

METHODS
The subjects were 933 apparently healthy adults (mean age, 56 ± 10 years). Radial pressure waveforms were recorded with applanation tonometry to estimate mean arterial pressure (MAP), cPP, forward and backward pressure amplitudes, and augmentation index. The urinary sodium/creatinine and albumin/creatinine ratios were measured in spot urine samples.

RESULTS
Both the urinary sodium/creatinine and albumin/creatinine ratios were positively correlated with cPP, even after adjusting for MAP (P &lt; 0.001). Moreover, both ratios had a synergistic influence on increasing the cPP independent of age, sex, estimated glomerular filtration rate, hyperlipidemia, and diabetes (interaction P = 0.04). A similar synergistic influence was found on the forward pressure amplitude, but not on the backward pressure amplitude or augmentation index. The overall results were not altered when the urinary albumin/creatinine ratio was replaced with the existence of chronic kidney disease (CKD).

CONCLUSIONS
(Micro)albuminuria strengthens the positive association between urinary sodium excretion and cPP and systolic forward pressure. Excess sodium intake may magnify the cardiovascular risk by widening the aortic pulsatile pressure, particularly in the presence of concomitant CKD.
Does brain size affect mate choice? An experimental examination in pygmy halfbeaks
Authors: McNeil Rebecca M , Devigili Alessandro , Kolm Niclas , Fitzpatrick John L 
Published: April 2021

Abstract
Choosing a mate is one of the most important decisions in an animal’s lifetime. Female mate choice is often guided by the presence or intensity of male sexual ornaments, which must be integrated and compared among potential mates. Individuals with greater cognitive abilities may be better at evaluating and comparing sexual ornaments, even when the difference in ornaments is small. While brain size is often used as a proxy for cognitive ability, its effect on mate choice has rarely been investigated. Here, we investigate the effect of brain size on mate preferences in the pygmy halfbeak Dermogenys collettei, a small freshwater fish that forms mixed-sex shoals where mating takes place. Pygmy halfbeaks are ideal models as their semi-transparent heads allow for external brain measurements. After validating the use of external measurements as a proxy for internal brain size, we presented females with large or small brains (relative to body length) with two males that had either a large or small difference in sexual ornamentation (measured by the total area of red coloration). Unexpectedly, neither total relative brain size nor relative telencephalon size affected any measured aspect of mate preference. However, the difference in male sexual ornamentation did affect preference, with females preferring males with a smaller area of red coloration when the difference in ornaments was large. This study highlights the complexities of mate choice and the importance of considering a range of stimuli when examining mate preferences.
Resolving diverse protein–DNA footprints from exonuclease-based ChIP experiments
Authors: Biswas Anushua , Narlikar Leelavati 
Published: April 2021

Abstract

Motivation
High-throughput chromatin immunoprecipitation (ChIP) sequencing-based assays capture genomic regions associated with the profiled transcription factor (TF). ChIP-exo is a modified protocol, which uses lambda exonuclease to digest DNA close to the TF-DNA complex, in order to improve on the positional resolution of the TF-DNA contact. Because the digestion occurs in the 5′–3′ orientation, the protocol produces directional footprints close to the complex, on both sides of the double stranded DNA. Like all ChIP-based methods, ChIP-exo reports a mixture of different regions associated with the TF: those bound directly to the TF as well as via intermediaries. However, the distribution of footprints are likely to be indicative of the complex forming at the DNA.

Results
We present ExoDiversity, which uses a model-based framework to learn a joint distribution over footprints and motifs, thus resolving the mixture of ChIP-exo footprints into diverse binding modes. It uses no prior motif or TF information and automatically learns the number of different modes from the data. We show its application on a wide range of TFs and organisms/cell-types. Because its goal is to explain the complete set of reported regions, it is able to identify co-factor TF motifs that appear in a small fraction of the dataset. Further, ExoDiversity discovers small nucleotide variations within and outside canonical motifs, which co-occur with variations in footprints, suggesting that the TF-DNA structural configuration at those regions is likely to be different. Finally, we show that detected modes have specific DNA shape features and conservation signals, giving insights into the structure and function of the putative TF-DNA complexes.

Availability and implementation
The code for ExoDiversity is available on https://github.com/NarlikarLab/exoDIVERSITY.

Supplementary information
Supplementary data are available at Bioinformatics online.
Tolerability of Cefazolin in Nafcillin-Intolerant Patients for the Treatment of Methicillin-Susceptible Staphylococcus aureus Infections
Authors: Gandhi Ankit M , Shah Megan D , Donohue Lindsay E , Cox Heather L , Eby Joshua C 
Published: April 2021

Abstract

Background
Non-immunoglobulin E (IgE)-mediated hypersensitivity reactions (HSRs) to nafcillin are commonly reported, but scarce data are available to guide appropriate antibiotic change following these reactions. Although cefazolin is an attractive therapeutic alternative in methicillin-susceptible Staphylococcus aureus (MSSA) infections when patients experience an HSR to nafcillin, more data are needed to evaluate the tolerability of cefazolin after switching from nafcillin. The purpose of this study was to describe the tolerability of cefazolin in patients who develop a suspected non-IgE-mediated HSR to nafcillin.

Methods
This was a retrospective, descriptive case series of patients who received nafcillin for an MSSA infection, experienced a suspected non-IgE-mediated HSR, and were switched to cefazolin between October 2015 and November 2019 at a single academic medical center. The primary objective was to identify the percentage of patients who completed cefazolin after experiencing a suspected non-IgE-mediated HSR to nafcillin.

Results
There were 80 patients with 87 prespecified non-IgE-mediated HSRs during the study period. Seventy-one (89%) patients completed cefazolin, with 53 (75%) of these patients completing at least 2 weeks of therapy. One patient was ultimately switched from cefazolin to daptomycin due to concern for treatment failure. Eight patients (10%) did not tolerate cefazolin after switching from nafcillin. Of these, 3 patients experienced an unrelated HSR, whereas 5 patients experienced the same non-IgE-mediated HSR that was attributed to nafcillin and discontinued cefazolin within 7 days. The most common HSR cited was immune-mediated nephritis; however, the majority were clinically presumed but did not meet objective diagnostic criteria.

Conclusions
Treatment with cefazolin after experiencing a suspected non-IgE-mediated HSR to nafcillin appears to be safe, even for patients requiring a prolonged duration of cefazolin.
Changes in Emergency Medical Services Before and During the COVID-19 Pandemic in the United States, January 2018–December 2020
Authors: Handberry Maya , Bull-Otterson Lara , Dai Mengtao , Mann N Clay , Chaney Eric , Ratto Jeff , Horiuchi Kalanthe , Siza Charlene , Kulkarni Aniket , Gundlapalli Adi V , Boehmer Tegan K 
Published: April 2021

Abstract

Background
As a result of the continuing surge of coronavirus disease 2019 (COVID-19), many patients have delayed or missed routine screening and preventive services. Medical conditions, such as coronary heart disease, mental health issues, and substance use disorder, may be identified later, leading to increases in patient morbidity and mortality.

Methods
National Emergency Medical Services Information System data were used to assess 911 emergency medical services (EMS) activations during 2018–2020. For specific activation types, the percentage of total activations was calculated per week, and Joinpoint analysis was used to identify changes over time.

Results
Since March 2020, the number of 911 EMS activations has decreased, while the percentages of on-scene death, cardiac arrest, and opioid use/overdose EMS activations were higher than prepandemic levels. During the early pandemic period, percentages of total EMS activations increased for on-scene death (from 1.3% to 2.4% during weeks 11–15), cardiac arrest (from 1.3% to 2.2% during weeks 11–15), and opioid use/overdose (from 0.6% to 1.1% during weeks 8–18). The percentages then declined but remained above prepandemic levels through calendar week 52.

Conclusions
The COVID-19 pandemic has indirect consequences, such as relative increases in EMS activations for cardiac events and opioid use/overdose, possibly linked to disruptions is healthcare access and health-seeking behaviors. Increasing telehealth visits and other opportunities for patient–provider touch points for chronic disease and substance use disorders that emphasize counseling, preventive care, and expanded access to medications can disrupt delayed care-seeking during the pandemic and potentially prevent premature death.
Heparin-free regional anticoagulation of haemodialysis filters with calcium-free dialysate: is citrate mandatory?
Authors: Medrano Chloé , Cointault Olivier , Lavayssiere Laurence , Nogier Marie-Béatrice , Colliou Eloïse , Setbon Nicolas , Kamar Nassim , Faguer Stanislas 
Published: April 2021

ABSTRACT

Background
There is an unmet need to develop safe and successful heparin-free regional anticoagulation modalities in haemodialysed patients at risk of bleeding. Whether the addition of citrate as a prefilter injection or in the dialysate itself is required to reach anticoagulation objectives when calcium-free dialysate is used as regional anticoagulation remains unclear.

Methods
In this monocentric retrospective study, we report our experience of 908 dialysis sessions performed with a calcium-free citrate-containing dialysate and calcium reinjection according to the ionic dialysance, without additional heparin.

Results
Premature termination for filter clotting occurred in 20 sessions (2.2%) and duration of session was &gt;4.5 h in 135 (15%; maximum duration 6 h). In addition, we could investigate the citrate, calcium and acid–basis status during haemodialysis sessions performed with (citrate group, n = 20 sessions) or without (citrate-free group, n = 19 sessions) citrate in the dialysate. In 20 sessions performed in patients with underlying liver disorders and using calcium-free citrate-containing dialysate, patients’ ionized calcium (iCa) and serum citrate levels were stable and remained within the normal range, respectively. Post-filter iCa was below 0.4 mmol/L in 19/20 sessions and citrate was 0.304 mmol/L (range: 0.011; 0.548). In 19 sessions that used calcium and citrate-free dialysate, post-filter iCa was 0.41 mmol/L (0.34; 0.5) and all sessions extended to 4 h or beyond.

Conclusions
Regional anticoagulation of haemodialysis with a calcium-free dialysate and calcium reinjection according to the ionic dialysance is safe. Adding citrate to the dialysate is not mandatory to prevent dialysis circuit clotting in most patients.