bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lateral migration of explosive hazards during maar eruptions constrained from crater shapes
Authors: Graettinger A. H. , Bearden A. T. 
Published: April 2021

AbstractMaar volcanoes are produced by subsurface phreatomagmatic explosions that can move vertically and laterally during an eruption. Constraining the distances that maar-forming explosions move laterally, and the number of relocations common to these eruptions, is vital for informing hazard scenarios and numerical simulations. This study uses 241 intact Quaternary maar crater shapes to establish global trends in size and spacing of explosion position relocations. Maar craters are sorted into shape classes based on the presence of uniquely identifiable combinations of overlapping circular components in their geometry. These components are used to recognize the minimum number of explosion locations responsible for observed crater shapes. Craters with unique solutions are then used to measure the size and spacing of the explosion footprints, the circular area of the largest crater produced by a single explosion of a given energy, that produce the crater shape. Thus, even in the absence of abundant observations of maar-type eruptions, the typical range, size and spacing of explosion positions are derived from maar crater shapes. This analysis indicates that most Quaternary maar eruptions involved at least three different explosion locations spanning distances of 200–600 m that did not always follow the trend of the dike feeding the eruption. Additional evaluation of larger maars, consistent with stratigraphic studies, indicates that centers of explosive activity, and thus the origin of ballistic and density current hazards, can move as many as twenty times during a maar-forming eruption. These results provide the first quantitative constraints on the scale and frequency of lateral migration in maar eruptions and these values can directly contribute to hazard models and eruption event trees in advance of future maar-type eruptions.
Synchronization in 5G networks: a hybrid Bayesian approach toward clock offset/skew estimation and its impact on localization
Authors: Goodarzi Meysam , Cvetkovski Darko , Maletic Nebojsa , Gutiérrez Jesús , Grass Eckhard 
Published: April 2021

AbstractClock synchronization has always been a major challenge when designing wireless networks. This work focuses on tackling the time synchronization problem in 5G networks by adopting a hybrid Bayesian approach for clock offset and skew estimation. Furthermore, we provide an in-depth analysis of the impact of the proposed approach on a synchronization-sensitive service, i.e., localization. Specifically, we expose the substantial benefit of belief propagation (BP) running on factor graphs (FGs) in achieving precise network-wide synchronization. Moreover, we take advantage of Bayesian recursive filtering (BRF) to mitigate the time-stamping error in pairwise synchronization. Finally, we reveal the merit of hybrid synchronization by dividing a large-scale network into local synchronization domains and applying the most suitable synchronization algorithm (BP- or BRF-based) on each domain. The performance of the hybrid approach is then evaluated in terms of the root mean square errors (RMSEs) of the clock offset, clock skew, and the position estimation. According to the simulations, in spite of the simplifications in the hybrid approach, RMSEs of clock offset, clock skew, and position estimation remain below 10 ns, 1 ppm, and 1.5 m, respectively.
Outage prediction for ultra-reliable low-latency communications in fast fading channels
Authors: Traßl Andreas , Schmitt Eva , Hößler Tom , Scheuvens Lucas , Franchi Norman , Schwarzenberg Nick , Fettweis Gerhard 
Published: April 2021

AbstractThe addition of redundancy is a promising solution to achieve a certain quality of service (QoS) for ultra-reliable low-latency communications (URLLC) in challenging fast fading scenarios. However, adding more and more redundancy to the transmission results in severely increased radio resource consumption. Monitoring and prediction of fast fading channels can serve as the foundation of advanced scheduling. By choosing suitable resources for transmission, the resource consumption is reduced while maintaining the QoS. In this article, we present outage prediction approaches for Rayleigh and Rician fading channels. Appropriate performance metrics are introduced to show the suitability for URLLC radio resource scheduling. Outage prediction in the Rayleigh fading case can be achieved by adding a threshold comparison to state-of-the-art fading prediction approaches. A line-of-sight (LOS) component estimator is introduced that enables outage prediction in LOS scenarios. Extensive simulations have shown that under realistic conditions, effective outage probabilities of$$10^{-5}$$10-5can be achieved while reaching up-state prediction probabilities of more than$${90}{\%}$$90%. We show that the predictor can be tuned to satisfy the desired trade-off between prediction reliability and utilizability of the link. This enables our predictor to be used in future scheduling strategies, which achieve the challenging QoS of URLLC with fewer required redundancy.
Afterload-related cardiac performance identifies cardiac impairment and associates with outcome in patients with septic shock: a retrospective cohort study
Authors: Chen Wei-yan , Zhang Zhen-hui , Tao Li-li , Xu Qi , Wei Xing , Chen Min-sheng 
Published: April 2021

Abstract
Background
Septic patients with cardiac impairment are with high mortality. Afterload-related cardiac performance (ACP), as a new tool for diagnosing septic cardiomyopathy (SCM), still needs to be evaluated for its impact on the prognosis for patients with septic shock.

Methods
In this retrospective study, 100 patients with septic shock undertaken PiCCO monitoring were included. The ability of ACP, cardiac index (CI), and cardiac power index (CPI) to discriminate between survivors and non-survivors was tested by comparing the area under the receiver operating characteristic curve (AUROC) analysis. Cox proportional hazards regression analyses were performed to assess the associations of ACP with day-28 mortality. Curve estimation was used to describe the relationship between the hazard ratio (HR) of death and ACP.

Results
ACP had a strong linear correlation with CI and CPI (P < 0.001). ACP demonstrated significantly greater discrimination for day-28 mortality than CI before adjusted [AUROC 0.723 (95% CI 0.625 to 0.822) vs. 0.580 (95% CI 0.468 to 0.692), P = 0.007] and CPI after adjusted [AUROC 0.693 (95% CI 0.590 to 0.797) vs. 0.448 (0.332 to 0.565), P < 0.001]. Compared with ACP > 68.78%, HR for ACP ≤ 68.78% was 3.55 (1.93 to 6.54) (P < 0.001). When adjusted with age, APACHE-II score, Vasoactive Inotropic Score, Lactate, CRRT, day-1 volume, fibrinogen and total bilirubin as possible confounders, and decrease ACP are still associated with increasing day-28 mortality (P < 0.05). An exponential relationship was observed between ACP12h and HR of day-28 death.

Conclusions
Our results suggested thatACP could improve mortality predictions when compared to CI and CPI. Decreased ACP was still an independent risk factor for increased day-28 mortality.
The first single-incision plus one-port transverse colon resection using Senhance Digital Laparoscopy System: a case report
Authors: Minagawa Yume , Hirano Yasumitsu , Kataoka Atsuko , Shimamura Satoshi , Kataoka Masahiro , Asari Masahiro , Fujii Takatsugu , Ishikawa Shintaro , Ishii Toshimasa , Sato Hiroshi , Sakuramoto Shinichi , Okamoto Kojun , Koyama Isamu 
Published: April 2021

Abstract
Background
We have introduced the Senhance Digital Laparoscopy System and actively use for colorectal cancer surgery. Recently, we also try to perform surgery by reduce port as less invasive method. For the first time, we report a case of single-incision plus one-port transverse colectomy using Senhance system.

Case presentation
The case was a 57-year-old woman, diagnosed with transverse colon cancer referred to our department. The preoperative diagnosis was cT1bN0M0, Stage I. We performed single-incision plus one-port transverse colon resection using Senhance system without any problems. The operative time was 203 min and the blood loss was 35 ml.

Conclusion
We report the first case of single-incision plus one-port transverse colectomy using Senhance system. We trust this approach will find increasing use, enabling a safer means of minimally invasive robotic surgery.
Pancreatic acinar cell carcinoma with extension into the main pancreatic duct: a case report
Authors: Kayahara Masato , Onishi Ichiro , Makita Naoki , Kano Shunsuke , Munemoto Masayoshi , Yagi Yasumichi , Minami Makiko , Orita Noriaki , Komura Takuya , Kurose Nozomu 
Published: April 2021

Abstract
Background
Pancreatic acinar cell carcinoma (PACC) is a rare exocrine malignant tumor. Its widespread intraductal extension into the main pancreatic duct (MPD) is also rare.

Case presentation
We report the case of a 71-year-old man with PACC with MPD extension. The patient was assessed with laboratory and radiographic investigations that facilitated a preoperative diagnosis. Endoscopic ultrasonography (EUS) and dynamic thin-slice multi-detector row computed tomography (MDCT) were useful for determining the resection line of the pancreas. EUS-guided fine needle aspiration (EUS-FNA) was also helpful in determining the tumor biology and treatment strategy. Distal pancreatectomy was performed. The MPD was occupied by the tumor 35 mm downstream and 5 mm upstream. Histopathologically, the pancreatic tail tumor extended continuously into the MPD. The tumor was solid with cells showing eosinophilic and granular cytoplasm, indicating the diagnosis of PACC. This is an interesting case of PACC with intraductal extension into the MPD. We discuss the possible mechanisms of tumor extension in this rare case together with a review of the literature.

Conclusions
We describe a rare pancreatic acinar cell carcinoma that could be adequately treated using preoperative precise imaging and histopathological evaluations. When an intraductal tumor extension in the MPD is encountered, the diagnosis of a rare pancreatic tumor should be considered, as in our case.
Successful laparoscopic treatment for sustained abdominal pain due to fish bone migrating into the neck of the pancreas: a case report and thinking about surgical approach through the literature review
Authors: Wang Yang , Luo Xianzhang , Zhang Jiefeng 
Published: April 2021

Abstract
Background
The majority of ingested foreign bodies pass through the gastrointestinal tract smoothly, with less than 1% requiring surgery. Fish bone could perforate through the wall of stomach or duodenum and then migrate to other surrounding organs, like the pancreas and liver.

Case presentation
We report herein the case of a 67-year-old male who presented with sustained mild epigastric pain. Abdominal computed tomography revealed a linear, hyperdense, foreign body along the stomach wall and pancreatic neck. We made a final diagnosis of localized inflammation caused by a fish bone penetrating the posterior wall of the gastric antrum and migrating into the neck of the pancreas. Upper gastrointestinal endoscopy was performed firstly, but no foreign body was found. Hence, a laparoscopic surgery was performed. The foreign body was removed safely in one piece and was identified as a 3.2-cm-long fish bone. The patient was discharged from the hospital on the fifth day after surgery without any postoperative complications.

Conclusion
Laparoscopic surgery has proven to be a safe and effective way to remove an ingested fish bone embedded in the pancreas.
Integration of PV system with SMES based on model predictive control for utility grid reliability improvement
Authors: Bakeer Abualkasim , Salama Hossam S. , Vokony Istvan 
Published: April 2021

AbstractThis paper describes the integration of a photovoltaic (PV) renewable energy source with a superconducting magnetic energy storage (SMES) system. The integrated system can improve the voltage stability of the utility grid and achieve power leveling. The control schemes employ model predictive control (MPC), which has gained significant attention in recent years because of its advantages such as fast response and simple implementation. The PV system provides maximum power at various irradiation levels using the incremental conductance technique (INC). The interfaced grid side converter of the SMES can control the grid voltage by regulating its injected reactive power to the grid, while the charge and discharge operation of the SMES coil can be managed by the system operator to inject/absorb active power to/from the grid to achieve the power leveling strategy. Simulation results based on MATLAB/Simulink® software prove the fast response of the system control objectives in tracking the setpoints at different loading scenarios and PV irradiance levels, while the SMES injects/absorbs active and reactive power to/from the grid during various events to improve the voltage response and achieve power leveling strategy.
Structural validation of the “Teacher’s report form” attention problems scale in a Brazilian sample
Authors: Pires Thiago , Rocha Marina , Assis Simone , Nobre Flavio 
Published: April 2021

Abstract
Background
Attention deficit hyperactivity disorder is one of the most common childhood neurodevelopmental syndromes. Although clinical evaluation is considered the gold standard in diagnosing psychiatric disorders, in epidemiological studies, this evaluation is rarely used for practical and financial reasons. Instead, psychometric instruments are used to screen for the disorders. In this case, it is essential to investigate whether these instruments are suitable for measuring the proposed problem. This study aims to verify the structural validation of the Attention Problems Scale of the Teacher’s Report Form (TRF).

Methods
A random sample of 445 TRF filled out by the teacher of children from São Gonçalo/RJ was selected. The confirmatory factor analysis was applied to validate some factor structures that have been raised in the literature. A second aspect analyzed was the use of structural equation models to verify the validated factorial structure’s relationship with some comorbidities.

Results
The bifactor model was the most suitable to explain the TRF child’s Attention Problems Scale’s factor structure. It presented the best-fit quality scores for confirmatory factor analysis than other tested structures. Although it presented good indicators for structural validity, some symptoms could be reassessed to have a more consistent instrument. The bifactor model as an explanatory structure in SEM was able to predict important mental health outcomes. These results are an additional validation to the bifactor model.

Conclusions
The results suggest the validity of the TRF’s Attention Problems Scale. The instrument’s factor structure was also appropriate because it corroborated most of the association’s assumptions between subtypes of attention problems and other aspects of mental health. The existence of screening scales adapted to Brazilian Portuguese can substantially impact many children who have difficulty learning. Also, the screening scales can be a useful tool for the health sector to facilitate referral to the professional to make the diagnosis.
A High Activity Level Is Required for Augmented Muscle Capillarization in Older Women
Authors: Gliemann Lasse , Rytter Nicolai , Yujia Liu , Tamariz-Ellemann Andrea , Carter Howard , Hellsten Ylva 
Published: April 2021

ABSTRACT

Purpose
This study aimed to evaluate the influence of lifelong regular physical activity on skeletal muscle capillarization in women.

Methods
Postmenopausal women, 61±4 yr old, were divided according to self-reported physical activity level over the past 20 yrs: sedentary (SED; n = 14), moderately active (MOD; n = 12), and very active (VERY; n = 15). Leg blood flow (LBF) was determined by ultrasound Doppler, and blood samples were drawn from the femoral artery and vein for calculation of leg oxygen uptake (LVO2) at rest and during one-legged knee extensor exercise. A skeletal muscle biopsy was obtained from the vastus lateralis and analyzed for capillarization and vascular endothelial growth factor (VEGF) and mitochondrial OXPHOS proteins. Platelets were isolated from venous blood and analyzed for VEGF content and effect on endothelial cell proliferation.

Results
The exercise-induced rise in LBF and LVO2 was faster (P = 0.008) in VERY compared with SED and MOD. Steady-state LBF and LVO2 were lower (P < 0.04) in MOD and VERY compared with SED. Capillary–fiber ratio and capillary density were greater (P < 0.03) in VERY (1.65 ± 0.48 and 409.3 ± 57.5) compared with MOD (1.30 ± 0.19 and 365.0 ± 40.2) and SED (1.30 ± 0.30 and 356.2 ± 66.3). Skeletal muscle VEGF and OXPHOS complexes I, II, and V were ~1.6-fold and ~1.25-fold (P < 0.01) higher, respectively, in VERY compared with SED. Platelets from all groups induced an approximately nine-fold (P < 0.001) increase in endothelial cell proliferation.

Conclusion
A very active lifestyle is associated with superior skeletal muscle exercise hemodynamics and greater potential for oxygen extraction concurrent with a higher skeletal muscle capillarization and mitochondrial capacity.
A pan-genome method to determine core regions of the Bacillus subtilis and Escherichia coli genomes
Authors: Sutton Granger , Fogel Gary B. , Abramson Bradley , Brinkac Lauren , Michael Todd , Liu Enoch S. , Thomas Sterling 
Published: April 2021

Background: Synthetic engineering of bacteria to produce industrial products is a burgeoning field of research and application. In order to optimize genome design, designers need to understand which genes are essential, which are optimal for growth, and locations in the genome that will be tolerated by the organism when inserting engineered cassettes. Methods: We present a pan-genome based method for the identification of core regions in a genome that are strongly conserved at the species level. Results: We show that the core regions determined by our method contain all or almost all essential genes. This demonstrates the accuracy of our method as essential genes should be core genes. We show that we outperform previous methods by this measure. We also explain why there are exceptions to this rule for our method. Conclusions: We assert that synthetic engineers should avoid deleting or inserting into these core regions unless they understand and are manipulating the function of the genes in that region. Similarly, if the designer wishes to streamline the genome, non-core regions and in particular low penetrance genes would be good targets for deletion. Care should be taken to remove entire cassettes with similar penetrance of the genes within cassettes as they may harbor toxin/antitoxin genes which need to be removed in tandem. The bioinformatic approach introduced here saves considerable time and effort relative to knockout studies on single isolates of a given species and captures a broad understanding of the conservation of genes that are core to a species.
Elution of rifampin and vancomycin from a weight-bearing silorane-based bone cement
Authors: Funk Grahmm August , Menuey Elizabeth M. , Ensminger William P. , Kilway Kathleen V. , McIff Terence E. 
Published: April 2021

AimsPoly(methyl methacrylate) (PMMA)-based bone cements are the industry standard in orthopaedics. PMMA cement has inherent disadvantages, which has led to the development and evaluation of a novel silorane-based biomaterial (SBB) for use as an orthopaedic cement. In this study we test both elution and mechanical properties of both PMMA and SBB, with and without antibiotic loading.MethodsFor each cement (PMMA or SBB), three formulations were prepared (rifampin-added, vancomycin-added, and control) and made into pellets (6 mm × 12 mm) for testing. Antibiotic elution into phosphate-buffered saline was measured over 14 days. Compressive strength and modulus of all cement pellets were tested over 14 days.ResultsThe SBB cement was able to deliver rifampin over 14 days, while PMMA was unable to do so. SBB released more vancomycin overall than did PMMA. The mechanical properties of PMMA were significantly reduced upon rifampin incorporation, while there was no effect to the SBB cement. Vancomycin incorporation had no effect on the strength of either cement.ConclusionSBB was found to be superior in terms of rifampin and vancomycin elution. Additionally, the incorporation of these antibiotics into SBB did not reduce the strength of the resultant SBB cement composite whereas rifampin substantially attenuates the strength of PMMA. Thus, SBB emerges as a potential weight-bearing alternative to PMMA for the local delivery of antibiotics. Cite this article: Bone Joint Res 2021;10(4):277–284.
Low risk of SARS-CoV-2 in blood transfusion
Authors: Owusu Michael , Sylverken Augustina Angelina , El-Duah Philip , Ayisi-Boateng Nana Kwame , Yeboah Richmond , Adu Eric , Asamoah Jesse , Frimpong Michael , Senyo Japhet , Acheampong Godfred , Mutocheluh Mohamed , Amuasi John , Owusu-Dabo Ellis , Adu-Sarkodie Yaw , Phillips Richard Odame 
Published: April 2021

Background
The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), continues to remain a global challenge. There is emerging evidence of SARS-CoV-2 virus found in the blood of patients from China and some developed countries. However, there is inadequate data reported in Ghana and other parts of Africa, where blood transfusion service heavily relies on voluntary and replacement blood donors. This study aimed to investigate whether plasma of infected individuals could pose significant transfusion transmitted risk of COVID-19 in Ghanaian populations.

Methods
This cross-sectional retrospective study was conducted at the Kumasi Centre for Collaborative Research into Tropical Medicine (KCCR), KNUST, Ghana. Study subjects comprised contacts of COVID-19 individuals, those with classical symptoms of COVID-19 and individuals who had recovered based on the new Ghana discharge criteria. Whole blood, sputum or deep coughed saliva samples were collected and transported to KCCR for SARS-CoV-2 testing. Viral nucleic acid was extracted from sputum/nasopharyngeal samples using Da An Gene column based kit and from plasma using LBP nucleic acid extraction kit. Real-Time PCR was performed specifically targeting the ORF1ab and Nucleocapsid (N) genomic regions of the virus.

Results
A total of 97 individuals were recruited into the study, with more than half being males (58; 59.7%). The mean age of all subjects was 33 years (SD = 7.7) with minimum being 22 years and maximum 56 years. Majority (76; 78.4%) of all the subjects were asymptomatic, and among the few symptomatic subjects, cough (10; 10.3%) was the most predominant symptom. Of the 97 sputum samples tested, 79 (81.4%) were positive for SARS-CoV-2. We identified SARS-CoV-2 viral RNA in the plasma of 1 (1.03%) subject who had clinically recovered.

Conclusion
This study reports the identification of SARS-CoV-2 viral RNA in a convalescent individual in Ghana. Due to the low prevalence observed and the marginal cycling thresholds associated, the risk of transfusion transmission of SARS-CoV-2 is negligible. Well-powered studies and advanced diagnostics to determine infectious viremia is recommended to further evaluate the potential risk of hematogenous transmission among recovered patients.