bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low bone density, vertebral fracture and FRAX score in kidney transplant recipients: A cross-sectional cohort study
Authors: Velioglu Arzu , Kaya Burcu , Aykent Basar , Ozkan Bige , Karapinar Melis Sevil , Arikan Hakki , Asicioglu Ebru , Bugdaycı Onur , Yavuz Dilek Gogas , Tuglular Serhan 
Published: April 2021

BackgroundKidney transplantation (KT) recipients are at increased risk of low bone density (LBD) and fractures. In this retrospective study, we investigated bone mineral density (BMD), vertebral fractures, calculated risk for major osteoporotic fractures (MOF), and hip fractures in the KT recipients.Patients-methodPatients who completed at least one year after KT were included in the analysis. Demographic, clinical, and laboratory data were recorded. Measurements of BMD were performed by dual-energy X-ray absorptiometry. Vertebral fractures were assessed using semi-quantitative criteria with conventional radiography. The ten-year risk for MOF and hip fracture were calculated using the FRAX@ tool with BMD.ResultsOne hundred fifty-three KT recipients were included in the study. The population included 77 women. The mean age at evaluation was 46,5±11,9 years. Seventy-eight (50.9%) patients had normal femoral neck BMD while osteoporosis and osteopenia at the femoral neck were present in 12 (7.8%) and 63 (41.1%) of the patients, respectively. Age at evaluation was the risk factor for LBD (OR 1.057; 95% CI 1.024–1.091; p = 0.001). In female KT recipients, LBD was principally affected by menopausal status whereas in males, mammalian target of rapamycin (mTOR) inhibitor use and lower BMI levels were the risk factors. The prevalent vertebral fracture was found in 43.4% of patients. In multivariate analysis, only steroid use (OR 0.121; 95% CI 0.015–0.988; p = 0.049) was found to be associated with prevalent fracture. Among all KT recipients, 1.9% had a high MOF probability (≥20% risk of fracture), and 23.5% had high hip fracture probability (≥3% risk of hip fracture) according to FRAX.ConclusionExploring the prevalence of LBD and vertebral fracture and the risk factors would help clinicians to modify long-term follow-up strategies. Furthermore, the high hip fracture risk probability in our cohort suggested that there is a need for longitudinal studies to confirm the validity of the FRAX tool in the transplant population.
Incidence and risk factors for urinary tract infections in the first year after renal transplantation
Authors: Velioglu Arzu , Guneri Gokhan , Arikan Hakki , Asicioglu Ebru , Tigen Elif Tukenmez , Tanidir Yiloren , Tinay İlker , Yegen Cumhur , Tuglular Serhan 
Published: May 2021

Background
The most common infections among renal transplant patients are urinary tract infections (UTI). Our main objective in this study is to determine the incidence of UTIs in patients who have undergone renal transplantation in our hospital, to identify the causative microbiological agents, risk factors and determine the effects of UTI on short-term graft survival.

Methods
Urinary tract infections, which developed within the first year of renal transplantation, were investigated. Patients were compared regarding demographic, clinical, laboratory characteristics and graft survival.

Results
102 patients were included in our study. Fifty-three patients (53%) were male and 49 (48%) were female. Sixty-seven urinary tract infection attacks in 21 patients (20.5%) were recorded. Age (p = 0.004; 95% Confidence Interval [CI]: 1.032–1.184), longer indwelling urinary catheter stay time (p = 0.039; 95% Confidence Interval [CI]: 1.013–1.661) and urologic complications (p = 0.006; 95% Confidence Interval [CI]: 0.001–0.320) were found as risk factors for UTI development in the first year of transplantation. Escherichia coli and Klebsiella pneumoniae were the most frequently isolated microorganisms. Of these bacteria, 63.2% were found to be extended spectrum beta lactamase (ESBL) positive. Multidrug resistant microorganisms (MDROs) were more frequent in male patients (32 episodes in males vs. 14 episodes in females, p = <0.001). UTI had no negative impact on short-term graft survival.

Conclusion
Our study results represent the high incidence of UTI with MDROs in KT recipients. Infection control methods should be applied even more vigorously especially in male transplant patients since a higher incidence of UTI caused by resistant microorganisms was reported in male patients.
Social Media Entertainment: The New Intersection of Hollywood and Silicon Valley, Stuart Cunningham and David Craig (2019)
Authors: Evens Tom 
Published: May 2021

Review of: Social Media Entertainment: The New Intersection of Hollywood and Silicon Valley, Stuart Cunningham and David Craig (2019)
New York: New York University Press, 368 pp.,
ISBN 978-1-47984-689-4, p/bk, $30.00
Effect of weed management practices on weed cover in field pea (pisum sativum l.)
Authors: Kristó István , Tar Melinda , Irmes Katalin , Vályi-Nagy Marianna , Rácz Attila , Szalai Dóra 
Published: April 2021

Field pea (Pisum sativum L.) are planted on small area in Hungary, although it is a precious source of protein (22-28%), and it also plays a significant role like a component in fodder mixture and green forage. It is a great part in crop rotation as a short growing-season legume. Furthermore, it has beneficial effects of nitrogen-fixing nodules being able to obtain N derived from air. One of the most critical limiting factors is to find out weed management practise for control of weeds in field pea.
Our field experiment was carried out on site of the National Agricultural Research and Innovation Centre, the Department of Field Crops Research in Öthalom for comparing weed management strategies by evaluate their efficacy and weed flora. We used 6 herbicides or herbicid combination and observed weed density in 5 times during the growing season.
The most important weeds were: common chickweed (Stellaria media), wild mustard (Sinapis arvensis), branching lackspur (Consolida regalis), meldweed (Chenopodium album). Among the treatments the highest weed cover was the weedy check, followed by Stomp Super, obtained maximum weed control and long lasting effect. With the application of Basagran 480 SL and Pulsar 40 SL have a significantly lower weed density was recorded than preemergence applications. In case of Corum application, it was the lowest weed cover of all even at harvesting time. According to our experiments use of Dash does not control weeds considerably.
Evaluating the Risk of Irreversible Intestinal Necrosis Among Critically Ill Patients With Nonocclusive Mesenteric Ischemia
Authors: Calame Paul , Winiszewski Hadrien , Doussot Alexandre , Malakhia Alexandre , Grillet Franck , Verdot Pierre , Vuitton Lucine , Ronot Maxime , Pili-Floury Sebastien , Heyd Bruno , Delabrousse Eric , Piton Gael 
Published: April 2021

INTRODUCTION:
To identify factors associated with irreversible transmural necrosis (ITN) among critically ill patients experiencing nonocclusive mesenteric ischemia (NOMI) and to compare the predictive value regarding ITN risk stratification with that of the previously described Clichy score.

METHODS:
All consecutive patients admitted to the intensive care unit between 2009 and 2019 who underwent exploratory laparotomy for NOMI and who had an available contrast-enhanced computed tomography with at least 1 portal venous phase were evaluated for inclusion. Clinical, laboratory, and radiological variables were collected. ITN was assessed on pathological reports of surgical specimens and/or on laparotomy findings in cases of open–close surgery. Factors associated with ITN were identified by univariate and multivariate analysis to derive a NOMI-ITN score. This score was further compared with the Clichy score.

RESULTS:
We identified 4 factors associated with ITN in the context of NOMI: absence of bowel enhancement, bowel thinning, plasma bicarbonate concentration ≤15 mmol/L, and prothrombin rate <40%. These factors were included in a new NOMI-ITN score, with 1 point attributed for each variable. ITN was observed in 6%, 38%, 65%, 88%, and 100% of patients with NOMI-ITN score ranging from 0 to 4, respectively. The NOMI-ITN score outperformed the Clichy score for the prediction of ITN (area under the receiver operating characteristics curve 0.882 [95% confidence interval 0.826–0.938] vs 0.674 [95% confidence interval 0.582–0.766], respectively, P < 0.001).

DISCUSSION:
We propose a new 4-point score aimed at stratifying risk of ITN in patients with NOMI. The Clichy score should be applied to patients with occlusive acute mesenteric ischemia only.
Classification of sleep apnea using EMD-based features and PSO-trained neural networks
Authors: Afrakhteh Sajjad , Ayatollahi Ahmad , Soltani Fatemeh 
Published: April 2021

Abstract
In this study, we propose a method for detecting obstructive sleep apnea (OSA) based on the features extracted from empirical mode decomposition (EMD) and the neural networks trained by particle swarm optimization (PSO) in the classification phase. After extracting the features from the intrinsic mode functions (IMF) of each heart rate variability (HRV) signal of each segment, these features were applied to the input of popular classifiers such as multi-layer perceptron neural networks (MLPNN), Naïve Bayes, linear discriminant analysis (LDA), k-nearest neighborhood (KNN), and support vector machines (SVM) were applied. The results show that the MLPNN learned with back propagation (BP) algorithm has a diagnostic accuracy of less than 90%, and this may be due to being derivative based property of the BP algorithm, which causes trapping in the local minima. For Improving MLPNN’s performance, we used the PSO algorithm instead of the BP method in training part. Therefore, the MLPNN’s accuracy improved from 89.36 to 97.66% after the application of the PSO algorithm. The proposed method has also reached to 97.78 and 97.96% in sensitivity and specificity, respectively. So, it can be concluded that the proposed method achieves better or comparable results when compared with the previous works in this field.
Effect of different types of soil tillage for sunflower on some soil physical characteristics. Part I: soil moisture
Authors: Yankov Peter , Drumeva Miglena 
Published: April 2021

Abstract
The investigation was carried out during 2014–2016 in the land of General Toshevo town in the South Dobrudzha region on slightly leached chernozem soil type. The effect of the types of soil tillage for sunflower given bellow was followed: ploughing at 24–26 cm, chisel-plough at 24–26 cm, disking with disk harrow at 10–12 cm and direct sowing (no-tillage) on the soil moisture content. Based on bulk density, wilting point and the determined soil moisture content the plant-available water was calculated. The additional soil tilths of the areas subjected to ploughing, chisel-ploughing and disking with disc harrow included double spring pre-sowing cultivation with harrowing. To destroy the emerging weeds in the variant with direct sowing, a total herbicide was applied. The soil moisture content was evaluated during three main stages of sunflower development: emergence, flowering and technical maturity. The investigated parameter was determined for each of the studied layers – 0–10, 10–20, 20–30, 30–40 and 40–60 cm. In years with normal amounts of rainfalls, no significant differences in the soil moisture under the different ways of soil tillage were observed. Conventional ploughing and tillage without turning of the soil layer contributed to accumulation of more moisture and to higher moisture storage down the soil profile under heavy and intensive rainfalls. Tillage without turning of the soil layer, minimal and no tillage maintained more and better soil moisture in years with limited precipitation and in periods of drought.
The Price of Nitrogen at the End of the Nineteenth Century
Authors: Page Arnaud , Herment Laurent 
Published: April 2021

Abstract
The second half of the nineteenth century was marked by the concomitant and entangled processes of the rise of agricultural chemistry and that of the fertiliser trade. Yet, while the two were undoubtedly related, the work of agricultural chemists was not necessarily characterized by the uniform and unequivocal promotion of fertilisers. This article looks at some of the complex ways in which chemists participated in the development of the fertiliser trade by studying how their work was used to ascribe a commercial price to a chemical element. It analyses the contested development of the idea that nitrogen, in particular, could be given a price, and shows how the rise of this quotation lay at the intersection of scientific and commercial considerations. More broadly, it argues that the importance of the new artificial fertilisers primarily lay not so much in yield increases as in inaugurating a new regime marked by a more comprehensive quantitative assessment of inputs and outputs, thereby playing a key role in the industrialisation of agriculture.
Die Gauwirtschaftsberater der NSDAP
Authors: Stremmel Ralf 
Published: April 2021

Abstract
At least 129 Gau economic advisers of the NSDAP worked at the intersection of politics and economics, wielding a considerable amount of power. At the regional level, they were able to have a say in the success and existence of corporations. The article examines this group’s organization and remit, as well as resources in power and capital. Along the lines of collective biographies, it covers the aspects of generation, origin, socioeconomic status, fluctuation, and entry into the Nazi party. While no homogenous type of Gau economic adviser or a pattern of action could be identified, the final part of the article outlines common aspects and presents five ideal types of Gau economic advisers.
Effect of l-carnitine supplementation on children and adolescents with nonalcoholic fatty liver disease (NAFLD): a randomized, triple-blind, placebo-controlled clinical trial
Authors: Saneian Hossein , Khalilian Leila , Heidari-Beni Motahar , Khademian Majid , Famouri Fatemeh , Nasri Peyman , Hassanzadeh Akbar , Kelishadi Roya 
Published: May 2021

Abstract

Objectives
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in the pediatric population at global level. Present study aims to assess the effect of l-carnitine supplementation on the NAFLD in children and adolescents.

Methods
This randomized, triple-blind, placebo-controlled clinical trial was conducted in 2018–2019. Study was carried out in NAFLD participants (5–15 years). They were randomly assigned to receive either 50 mg/kg/day l-carnitine twice a day or identical placebo per day for three months. Liver enzymes and liver ultrasonography were assessed before and after the intervention. Both groups received similar consultation for lifestyle changes.

Results
Overall, 55 participants completed the study, 30 patients in the l-carnitine group and 25 patients in placebo group. Mean changes of anthropometric measurements did not have significant differences between groups (p>0.05). No significant differences in the mean changes of aspartate aminotransferase (AST) (p=0.82) and alanine aminotransferase (ALT) (p=0.76) levels were documented between two groups. Based on within-group analysis, there were significant changes in AST and ALT levels before and after the intervention in both groups. The sonographic grades of fatty liver were not significantly different between two groups before (p=0.94) and after intervention (p=0.93).

Conclusions
In the present clinical trial, L-carnitine did not have significant effect on improving biochemical and sonographic markers of NAFLD in children and adolescents. Future studies are necessary to evaluate the applicability and efficacy of long-term l-carnitine supplementation to treatment of NAFLD in pediatric population.

Trial registration
IRCT20170628034786N2.
Synthesis and crystal structure of poly[(μ3-2-(2-carboxylatophenyl)-1H-benzo[d]imidazole-5-carboxylato-κO,O′:O′;:O″, O″′)-(μ2-1-(4-(1Himidazol-1-yl)phenyl)-1H-imidazole-κ2N:N′)cadmium(II)], C27H18CdN6O4
Authors: Yang Qing-Lin , Fu Peng-Kun , Xiong Ding-Qi , Zhang Xiao-Yu , Jia Mei-Mei , Dong Xiu-Yan 
Published: May 2021

Abstract
C27H18CdN6O4, triclinic,

P

1
‾

$P&#x203e;{1}$

(no. 2), a = 10.2994(8) Å, b = 10.7795(7) Å, c = 11.0038(7) Å, α = 89.778(5)°, β = 78.046(6)°, γ = 83.049(6)°, Z = 2, V = 1186.11(14) Å3, R

gt
(F) = 0.0402, wR

ref
(F
2) = 0.0809, T = 293 K.
Chemical computational approaches for optimization of effective surfactants in enhanced oil recovery
Authors: Banerjee Tandrima , Samanta Abhijit 
Published: May 2021

Abstract
The surfactant flooding becomes an attractive method among several Enhanced Oil Recovery (EOR) processes to improve the recovery of residual oil left behind in the reservoir after secondary oil recovery process. The designing of a new effective surfactant is a comparatively complex and often time consuming process as well as cost-effective due to its dependency on the crude oil and reservoir properties. An alternative chemical computational approach is focused in this article to optimize the performance of effective surfactant system for EOR. The molecular dynamics (MD), dissipative particle dynamics (DPD) and density functional theory (DFT) simulations are mostly used chemical computational approaches to study the behaviour in multiple phase systems like surfactant/oil/brine. This article highlighted a review on the impact of surfactant head group structure on oil/water interfacial property like interfacial tensions, interface formation energy, interfacial thickness by MD simulation. The effect of entropy in micelle formation has also discussed through MD simulation. The polarity, dipole moment, charge distribution and molecular structure optimization have been illustrated by DFT. A relatively new coarse-grained method, DPD is also emphasized the phase behaviour of surfactant/oil/brine as well as polymer-surfactant complex system.
Identification of potential histone deacetylase inhibitory biflavonoids from Garcinia kola (Guttiferae) using in silico protein-ligand interaction
Authors: Adewole Kayode E. , Ishola Ahmed A. , Omolaso Blessing O. 
Published: May 2021

Abstract
Overactivity of histone deacetylases (HDACs) is the underlying cause of some cancers, thus, inhibiting their overactivities is a rational treatment option. However, endeavors to employ current anti-HDACs agents in cancer treatment have yielded limited success. Consequently, there is need to explore anti-HDACs natural products, especially from plants sources, because of the intimate relationship plant products and drug discovery have enjoyed over the centuries. To identify possible HDACs inhibitors, Garcinia kola (Guttiferae) seed-derived compounds were screened in silico for HDAC-inhibitory tendencies because of their reported anticancer potentials. Fifteen G. kola-derived compounds and givinostat were docked with five selected HDACs using AutodockVina, while the binding interactions of the compounds with high binding affinities for the five HDACs were viewed with Discovery Studio Visualizer BIOVIA, 2016. Results indicated that four of the compounds studied, including amentoflavone, Garcinia biflavonoid 1, Garcinia biflavonoid 2 and kolaflavanone have higher binding propensity for all the five HDACs relative to givinostat, the standard HDAC inhibitor. This study indicated that inhibition of HDAC might be another key mechanism accountable for the bioactivities of G. kola and its intrinsic compounds. The results from this study implied that the compounds could be further investigated as drugable HDAC inhibitors with potential pharmacological applications in the treatment of cancers.
Heart rate variability in patients with low back pain: a systematic review
Authors: Bandeira Pamela M. , Reis Felipe J.J. , Sequeira Vanessa C.C. , Chaves Anna C.S. , Fernandes Orlando , Arruda-Sanchez Tiago 
Published: April 2021

Abstract

Objectives
Heart rate variability (HRV) is an important physiological measure of the capacity for neurogenic homeostatic regulation, and an indirect measure of emotional processing. We aimed to investigate whether HRV parameters are altered in people with chronic low back pain when compared to healthy controls.

Methods
We searched on PubMed, Scopus, CINAHL, Web of Science, Cochrane Library, and PsycINFO from inception to January 2018. The inclusion criteria were: patients with non-specific chronic low back pain, absence of radiculopathy, age from 18 to 65 years, and comparison with healthy controls. Data extraction was performed by two independent review authors. The methodological quality of the studies was assessed using the appraisal tool for cross-sectional studies.

Results
After screening 2,873 potential articles, two studies met the inclusion criteria. Studies were composed of 153 patients with chronic low back pain and 62 healthy controls. An electrocardiogram was used to record HRV and linear methods (time and frequency) were used to analyze the results. The main findings indicate that patients with chronic low back pain have a significant reduction in HRV, with sympathetic predominance compared to healthy controls.

Conclusions
There is limited evidence suggesting that chronic low back pain patients presented a lower vagal activity evidenced by HRV, when compared to healthy controls. The results of this systematic review should be interpreted with caution due to the restricted number of included studies, small sample sizes and different protocols used to measure HRV. The limited evidence about HRV alterations in low back pain also suggests the need of future studies to investigate if HRV parameters can be a useful measure in chronic pain samples or even if it can be used as an outcome in clinical trials aiming to investigate the effectiveness of interventions based on emotion regulation.
Comparing optimization methods for deep learning in image processing applications
Authors: Geng Alexander , Moghiseh Ali , Redenbach Claudia , Schladitz Katja 
Published: May 2021

Abstract
Training a deep learning network requires choosing its weights such that the output minimizes a given loss function. In practice, stochastic gradient descent is frequently used for solving the optimization problem. Several variants of this approach have been suggested in the literature. We study the impact of the choice of the optimization method on the outcome of the learning process at the example of two image processing applications from quite different fields. The first one is artistic style transfer, where the content of one image is combined with the style of another one. The second application is a real world classification task from industry, namely detecting defects in images of air filters. In both cases, clear differences between the results of the individual optimization methods are observed.