bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trastorno por déficit de atención e hiperactividad y su prevalencia en estudiantes de Medicina de la Universidad Autónoma de Aguascalientes
Authors: Cienfuegos-Meza J , Gaytán-Magaña J J , Hermosillo-Pérez S N , Martínez-Sánchez A E , Oropeza-Prieto A , Rodríguez-Mendoza R L , Rodríguez-Pérez Diana , Villalobos-Peña F J , García-Huízar M P , Terrones-Saldívar M C 
Published: March 2021

El objetivo de este trabajo fue describir la prevalencia del trastorno de déficit de atención e hiperactividad en estudiantes de la carrera de Medicina de la Universidad Autónoma de Aguascalientes. Material y métodos: Se encuestaron estudiantes de los semestres primero, tercero, sexto, octavo y décimo de la carrera de Médico Cirujano de la Universidad Autónoma de Aguascalientes, mediante la Sección A de la Escala de Auto-Reporte de Síntomas de TDAH en Adultos (ASRS-v1.1). Se tomaron las variables de edad, sexo y semestre. De acuerdo a la edad se clasificaron los siguientes grupos: Grupo I (18 años), Grupo II (19 años), Grupo III (20 años), Grupo IV (21 años), Grupo V (22 años), Grupo VI (23 años) y Grupo VII (24 años). Resultados: Se encuestaron un total de 99 estudiantes, el promedio de edad fue de 20.5 años (Rango 18 a 24 años), 42.4% mujeres (n=42) y 57.6% hombres (n=57). Se encontró a 28 estudiantes (28.2%) con puntuación mayor a 4 en la sección A de la escala de evaluación. Dentro de este grupo, se obtuvo por género femenino (35.7%, n=10) y masculino (64.3%, n=18). La prevalencia de TDAH fue mayor en los estudiantes de los semestres más avanzados de la carrera de Médico Cirujano, lo que nos sugiere la influencia del estrés sobre la prevalencia de este trastorno.
Impacto sobre el índice de masa corporal en niños con leucemia aguda linfoide apoyados o no con un plan alimentario en el Centenario Hospital Miguel Hidalgo de la ciudad de Aguascalientes
Authors: Serrano-López Mario Alberto , Rubalcava-Rodríguez Martha , Galindo-López Claudia , Bernal-Macías Karla Patricia , Serna B , De Anda-de Lira Karina , Pérez-Maldonado Ricardo , Rosas-Cabral Alejandro 
Published: March 2021

La leucemia aguda linfoblástica es la primera causa de mortalidad por cáncer en menores de 15 años en nuestro país y en nuestro estado. La intervención nutricional, que acompaña el tratamiento oncológico, se debe centrar principalmente en la optimización del balance entre el gasto energético y la ingesta; para alcanzar objetivos específicos tales como: disminución de la tasa de complicaciones, mejorar la respuesta y la tolerancia al tratamiento oncológico. Material y métodos:Aquí reportamos un estudio prospectivo, longitudinal, aleatorio y con cegamiento simple, en el que estudiamos a 23 pacientes con leucemia aguda linfoblástica, de los cuales se les brindó apoyo con un plan alimentario a 12 y 11 se consideraron como controles. La variable en estudio fue el IMC antes y después del tratamiento. Se realizó estadística descriptiva y se empleó T de Student para comparación de medias, se consideró significancia con una p<0.05. Resultados: De los pacientes a los cuales se les asignó un plan alimentario, el promedio de IMC inicial fue de 17.16 ±3.81kg/m2 y el final de 17.34±3.69kg/m2, por lo que el incremento observado fue de 0.18kg/m2 en un lapso de 2 meses. En tanto, en los pacientes a los que no se brindó plan alimentario se obtuvo un IMC inicial de 16.87kg/m2 y uno final de 16.80kg/m2, el cual disminuyó 0.07kg/m2 en el mismo lapso de tiempo. Al comparar los resultados, no encontramos diferencias significativas (p=0.86), sin embargo, estos resultados nos sugieren que el plan alimentario puede contribuir a mantener las reservas corporales nutricionales en estos pacientes.LUX MÉDICA, AÑO 8, NÚMERO 23, PP 57-64
Comparación del estrés oxidativo en mujeres con diabetes gestacional versus embarazos normoevolutivos
Authors: Terrones Saldívar Ma del Carmen , Rodríguez Martín Gustavo , Rosas Cabral Alejandro , Góngora Ortega Javier , Serna Vela Francisco , Reyes Robles Martha Elena , Sandoval Valdez Darío Alejandro , Hernández González Flavio , De la Rosa Félix Hesli Esther , Zúñiga Sánchez Karina Altagracia 
Published: March 2021

Introducción: En la paciente con diabetes gestacional (DMG), la hiperglucemia favorece la aparición de estrés oxidativo, que a su vez es un factor que puede afectar adversamente al producto de la gestación. Objetivo: Medir y comparar la presencia del metabolito malondialdheído (MDA) y la actividad de las enzimas catalasa y superóxido dismutasa en un grupo de pacientes con diabetes gestacional versus mujeres con embarazos normoevolutivos. Material y métodos: Estudio prospectivo, comparativo y transversal, realizado en la ciudad de Aguascalientes de enero a junio de 2017. Muestreo por conveniencia, no probabilístico; pacientes distribuidas en dos grupos, el primero corresponde a 30 controles y el segundo representa 36 pacientes con diabetes gestacional. Previo consentimiento informado y mediante punción venosa se obtuvo una muestra de sangre para determinar mediante técnicas estandarizadas MDA, catalasa y superóxido dismutasa (SOD). Resultados: Las muestras de las pacientes embarazadas con diabetes tuvieron menor actividad enzimática de la SOD (120.0 UAE/ml/min) en comparación con las pacientes sin diabetes (193.1 UAE/ml/min). La actividad de la catalasa en las pacientes con DMG fue de 1.368µM H2O2/ml/min mientras que en las mujeres sin DMG fue 3.730µM de H2O2/ml/min. Las pacientes con DMG mostraron un valor de 19.19 µMol de MDA, mientras que el grupo control sin DMG tuvo un valor de 11.81µMol. Conclusión: los resultados de las pacientes con diabetes mellitus arrojaron que la patología incrementa la concentración de malondialdehído y catalasa, mientras que disminuye la actividad de la SOD respecto con las pacientes sin dicha patología
Absceso cerebral en paciente pediátrico: reporte de un caso
Authors: Barajas-Salcedo Gerardo , Macías Macías José Efraín 
Published: March 2021

El absceso cerebral ocurre rara vez en la edad pediátrica, pero en países en vías de desarrollo representa todavía un problema de salud que debe atenderse. En la mayoría de estos pacientes, se tiene como enfermedad asociada a una infección de senos paranasales. Aunque con la introducción de los antibióticos y las pruebas de imagen ha disminuido notablemente la mortalidad, es importante el diagnóstico temprano y oportuno que requiere esta patología para delimitar el daño y disminuir la morbilidad, misma que es también visible en la trascendencia emocional del núcleo familiar y el impacto económico que causa al sistema de salud responsable. Presentamos un caso clínico de un paciente pediátrico en el Hospital Miguel Hidalgo, de la ciudad de Aguascalientes, para demostrar la importancia del manejo integral y multidisciplinario que necesitan estos pacientes.
ARS MÉDICA AÑO 13, NÚMERO 37, SEPTIEMBRE 2017-ABRIL 2018
Authors: De la Torre Alcocer José 
Published: March 2021

Espacio dedicado a escritores y artistas, miembroso no, de la comunidad médica, quienes podrán aportar textos y obras artísticas que contribuyan a mejorar la cultura en salud de la comunidad. Publicación financiada con recursos PFCE 2017
The Effect of Ankle Strategy Exercises on Static Balance in The Elderly
Authors: Yuniar Ramadhani Dwi , Arivia Putri 
Published: March 2021

Decreased muscle strength is a musculoskeletal disorder in the elderly, resulting in slow movements and impaired physical mobility. Physical changes that occur in the elderly cause the risk of falling. This study analyzes the ankle strategy exercise's effect on static balance in the elderly at Regional Technical Implementation Unit (UPTD) Griya Werdha Surabaya.
This study was Pre-Experimental with One Group Pre-Post Test Design. From the population, there were thirty-five respondents by simple random sampling. This study's independent variable was ankle strategy exercises with frequency three times a week within a month. The dependent variable was a static balance with the instrument Time Up Go (TUG) test. The authors analyzed the data with the Wilcoxon test.
The study results showed a significant effect of the ankle strategy exercise on static balance in the elderly (p=0,000). The result showed a decrease in the number of elderly who have the high-risk of falling before the ankle strategy exercise (60% of elderly have a high risk of falling) and after the intervention (34% of elderly have a decreased risk of falling).
The elderly should do the ankle strategy exercise independently or with assistant three times a week to improve their static balance and decrease their high-risk of falls.
A Stepwise Approach to Identify the Clinical Role of FDG PET-CT in Patients with Suspicious Bone Metastasis from an Unknown Primary Site
Authors: Chowdhury Md Sunny Anam , Jeon Subin , Jabin Zeenat , Bom Hee Seung , Min Jung Joon , Kwon Seong Young 
Published: March 2021

Objectives: In patients with suspicious bone metastasis, differential diagnosis and primary lesion identification is very important in optimizing treatment planning. The study was aimed to assign a step-wise approach based on image findings to identify the precise role of PET-CT in these patients.
Patients and Methods: A total of 74 patients were enrolled with suspicious bone metastasis who underwent PET-CT for the evaluation of primary focus. Patients were classified into four groups with stepwise manners, firstly based on FDG positivity of bone lesions, then on multiplicity of positive bone uptake and finally on presence of extra-skeletal uptake. We analyzed the difference of distribution of follow-up results according to each group. In addition, we also investigated whether PET-CT had a role to guide biopsy sites.
Results: Except for 7 patients without bone or extra-skeletal uptake, 44 patients were categorized in multiple bone and extra-skeletal uptake group (A), 12 in multiple bone uptake without extra-skeletal uptake group (B), 3 in single bone and extra-skeletal uptake group (C) and 8 in single bone uptake without extra-skeletal uptake group (D). In group A, 42/44 patients had metastatic bone disease; where primary lesion was correlating extra-skeletal uptake in 40 (91.0%) cases. Among the 12 patients of group B, 5 (41.7%) had primary malignant bone disease, 3 (25.0%) had benign bone lesions and 4 (33.3%) had metastatic bone disease but PET-CT failed to indicate the primary site. In group C, PET-CT positive extra-skeletal uptake sites were confirmed as primary lesions in all the 3 patients. Among the 8 patients of group D, 5 (62.5%) were benign bone disease, one (12.5%) was high grade sarcoma and the remaining two (25.0%) were metastatic bone disease where PET-CT failed to identify primary site. Additionally, there was significant (P = 0.0003) difference in prevalence of biopsy sites performed according to the presence of extra-skeletal uptake in PET-CT.
Conclusion: Clinical impact of PET-CT was different according to groups classified with stepwise manners, which suggested that different strategies should be taken especially when there was not extra-skeletal uptake to optimize management plan. PET-CT also had a significant role in patients with extra-skeletal uptake lesion through guidance of easily approachable biopsy sites.
Bangladesh J. Nuclear Med. 22(2): 95-102, Jul 2019
Solitary Liver Metastasis from Follicular Variant Papillary Thyroid Carcinoma: A Case Report
Authors: Perveen Rahima , Ferdous Jasmin , Quddus Sharmin , Mandal Tapati 
Published: March 2021

Papillary and follicular thyroid carcinomas, together known as differentiated thyroid carcinomas (DTC), are among the most curable of cancers. Distant metastases are rare events at the onset of DTC. Sites of metastases from follicular thyroid cancer (FTC) are usually osseous, and those from papillary thyroid cancer (PTC) metastasize to regional nodal basins and the lungs. Visceral metastases are rare, but the involvement of multiple sites has been reported so far. Liver metastases from differentiated thyroid carcinoma (LMDTC) are rare.We present the case of a patient with follicular variant of papillary thyroid carcinoma (FVPTC) unusually involving the liver.
Bangladesh J. Nuclear Med. 22(2): 146-149, Jul 2019
Body Mass Index and Common Geriatric Health Problems Among Elderly Retired Armed Forces Personnel
Authors: Khan Md Nasirul Haque , Kabir Md Iqbal , Khan Fatema Zerin 
Published: March 2021

Background: Aging is universal and it is inescapable. Health problems of elderly people are a global emerging issue. Body mass index (BMI) is a test often used to help medical professiona ls to assess nutritional status along with overall fitness and risk for disease in elderly. This study was conducted to assess the BMI and common geriatric health problems among elderly retired armed forces personnel.
Methods: This cross-sectional study was conducted among purposively selected 226 elderly retired armed forces personnel in both outpatient and inpatient departments of the Combined Military Hospital (CMH), Dhaka Cantonment from July 2018 to Jun e 2019. The study aimed to assess the association between BMI and common geriatric health problems. A questionnaire comprising of all the variables of interest were developed and used for data collection by face to face interview. Data were also collected by physical measurement and reviewing medical documents of the participants.
Results: Among the participants, majority (32.3%) had BMI c:25, 31 .9 % had 23-24.9, 30. 1 % had 18.5-22.9 and 5.8% had <18 .5 BMl group. Average number of morbidities perparticipant was 2.59. Out of all , 20.5% had hypertension, 13. 7% had heart disease , 13.1 % had diabetes, 1 2.5% had respiratory disease, 8.4% had dental disease, 7.5% had cataract, 7.5% had prostate enlargement, 5.8% had cancer, 5.6% hadarthritis and 5.5% hadear disease. Association of BMI of participants with hypertensi on, heart disease was found statistically significant (p<0.05). No significant association was found with diabetes and respiratory disease ( p<0.05).
Conclusion: Nutritional status of the elderly should be emphasized for prevention and control of health problems in retired armed forces elderly; for that BMl could be crucial indicator.
JOPSOM 2020; 39(1): 14-20
Socio-Economic Status and Depression Amongst the Urban Adolescents
Authors: Datta Dipa , Rahman Md Shafiur , Hamid Shaheda 
Published: March 2021

Background: Depression is a state of low mood and aversion to activity that can affect a person's thought, behavior feelings and physical wellbeing. Mental health of adolescents has been drawn going attention due to sustain increase in adolescent depression as well as suicidal incidence. The study aimed to determine the level of depression among the urban adolescents and its association with socio-economic status (SES).
Methods: A descriptive cross-sectional study was carried out among 384 adolescent students of selected English and Bangla medium school of Dhaka city during January to December 2016. A semi-structured questionnaire and convenience sampling technique were used for data collection. Data were analyzed using SPSS software.
Results: The study findings revealed that a large number of adolescents (34.11%) had depression and females are more (80%) prone to be depressed. Socio-economic status had significant association with the level of depression (p- 0.000). Out of 131 depressed respondents, 58.77%, 28.24%, 12.97% were in middle, upper and lower class respectively. Among all the depressed adolescents, 67.93% found significant depression and (32.06%) found cutoff score of depression.
Conclusion: This study showed that depression is remained uncared health problem among the adolescents due to socio-economic problem. More attention and awareness need at the national level for early diagnosis of Adolescent depression.
JOPSOM 2020; 39(1): 21-25
Salinity in drinking water and blood pressure status of adolescent school children in coastal area of Bangladesh
Authors: Hossain Irin , Khan Manzurul Haque 
Published: March 2021

Background: High dietary salt intake from food is a major risk factor for raised blood pressure (BP) worldwide. In the context of Bang ladesh , information regarding salinity in water and blood pressure especially in the adolescent population is very scarce. This study was conducted to assess the blood pressure status of adolescent school children in coastal area of Bangladesh.
Methods: A one-year school based cross-sectional study was carried out among 528 students of class 8-10 at schools of Bajua Union, Dacope Upazilla, saline prone zone of Khulna district. Relevant data were collected by using pre tested semi-structured questionnaire with face to face interview & checklist. Blood pressure was mea sured in a controlled environment and Collected water sources were analyzed by DPHE, Water Testing Laboratory. The study was conducted in the schools of Bajua Uni on, Dacope Upa zilla of the saline prone zone of Khulna district in between a one-year time frame.
Results: Among 528 participants most of them were male (353, 66.9%) with an age of 14 years (185 , 35.0%). Most of them were read in class 8 (185 , 35.0%). Prevalence of paternal, maternal, paternal grandparents' and maternal grandparents' history of hypertension were found significant. About 72.3% regularly took extra salt during meal and 43.9% took salt preserved fish with meal. Mean of systolic blood pressure of respondents were 114.2197 ± 7.61448 mm of Hg. Mean of diastolic blood pressure of respondents were 75.1 780 ± 5.45959 mm of Hg. Mean of pulse pressure of respondents were 39.0417 ± 6.56430. Mean of mean arterial pressure of respondents were 88. I 9 I 9 ± 5.44267 mm of Hg. Sodium concentration of pond were approximately in between 500-600 mg/I, whereas in tube wells approximately in between 700-1 I 00 mg/I.
Conclusion: Drinking water sodium is an important source of daily sodium intake , and therefore a risk factor for increased BP in salinity prone coastal areas. This adds to the cardiovascular health risks associated with food sodium intake in Southeast Asian populations. Low- saline alternative drinking water sources could effectively help to prevent high BP and hypertension-related morbidity and mortality in these coastal populations. New technologies for the supply of such alternative sources, including safeguarding the microbial quality , should be further studied.
JOPSOM 2020; 39(1): 60-66
Multiparametric vs. Inferior Vena Cava–Based Estimation of Right Atrial Pressure
Authors: Toma Matteo , Giovinazzo Stefano , Crimi Gabriele , Masoero Giovanni , Balbi Manrico , Montecucco Fabrizio , Canepa Marco , Porto Italo , Ameri Pietro 
Published: March 2021

Background: Right atrial pressure (RAP) can be estimated by echocardiography from inferior vena cava diameter and collapsibility (eRAPIVC), tricuspid E/e′ ratio (eRAPE/e′), or hepatic vein flow (eRAPHV). The mean of these estimates (eRAPmean) might be more accurate than single assessments.Methods and Results: eRAPIVC, eRAPE/e′, eRAPHV (categorized in 5, 10, 15, or 20 mmHg), eRAPmean (continuous values) and invasive RAP (iRAP) were obtained in 43 consecutive patients undergoing right heart catheterization [median age 69 (58–75) years, 49% males]. There was a positive correlation between eRAPmean and iRAP (Spearman test r = 0.66, P &lt; 0.001), with Bland–Altman test showing the best agreement for values &lt;10 mmHg. There was also a trend for decreased concordance between eRAPIVC, eRAPE/e′, eRAPHV, and iRAP across the 5- to 20-mmHg categories, and iRAP was significantly different from eRAPE/e′ and eRAPHV for the 20-mmHg category (Wilcoxon signed-rank test P = 0.02 and P &lt; 0.001, respectively). The areas under the curve in predicting iRAP were nonsignificantly better for eRAPmean than for eRAPIVC at both 5-mmHg [0.64, 95% confidence interval (CI) 0.49–0.80 vs. 0.70, 95% CI 0.53–0.87; Wald test P = 0.41] and 10-mmHg (0.76, 95% CI 0.60–0.92 vs. 0.81, 95% CI 0.67–0.96; P = 0.43) thresholds.Conclusions: Our data suggest that multiparametric eRAPmean does not provide advantage over eRAPIVC, despite being more complex and time-consuming.
Neoadjuvant Chemoradiotherapy Does Not Contribute to Worse Survival in Pathological Node-Negative Rectal Cancer
Authors: Huang Yong , Wei Wei , Wang Zhenguang , Liang Tao , Tian Shuyun , Fu Guangshun 
Published: March 2021

Purpose: The prognostic significance of ypN0 rectal cancer with comparison to pN0 disease still remains poorly defined. This study aimed to compare the prognosis of ypN0 and pN0 rectal cancer.Methods: Eligible patients were identified from the SEER18 registries research database (the latest data up to date was on April 15, 2019). Propensity score (PS) matching was usually performed to reduce the imbalance and potential confounding that were introduced by inherent differences between the groups. The cause-specific survival (CSS) was analyzed to evaluate the prognostic prediction of ypN0 and pN0 groups using the Kaplan–Meier method with the log-rank test. Cox proportional hazard model was also used to identify independent prognostic variables.Results: In total, 26,832 patients diagnosed with pN0 or ypN0 rectal cancer were confirmed as the final cohort, including 7,237 (27.0%) patients with radiation and 19,595 (73.0%) patients without radiation prior to surgery. The median follow-up time was up to 81 months. After adjusting for other prognostic factors, neoadjuvant radiotherapy was not an independent prognostic variable of CSS (HR = 1.100, 95%CI = 0.957–1.265, P = 0.180, using pN0 group as the reference).Conclusions: ypN0 rectal cancer was strongly associated with worse pathological diagnoses compared with pN0 rectal cancer, contributing to worse oncologic outcomes. However, the receipt of neoadjuvant chemoradiotherapy was not an independent prognostic factor of worse prognosis in pathological node-negative patients. Our study could give guidance to the treatment of ypN0 rectal cancer.
Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome
Authors: Wang Junling , Liu Zhimei , Xu Manting , Han Xiaodi , Ren Changhong , Yang Xinying , Zhang Chunhua , Fang Fang 
Published: March 2021

3-Hydroxyisobutyryl-CoA hydrolase (HIBCH, NM_014362.3) gene mutation can cause HIBCH deficiency, leading to Leigh/Leigh-like disease. To date, few case series have investigated the relationship between metabolites and clinical phenotypes or the effects of treatment, although 34 patients with HIBCH mutations from 27 families have been reported. The purpose of this study was to analyze the phenotypic spectrum, follow-up results, metabolites, and genotypes of patients with HIBCH deficiency presenting with Leigh/Leigh-like syndrome and explore specific metabolites related to disease diagnosis and prognosis through retrospective and longitudinal studies. Applying next-generation sequencing, we identified eight patients with HIBCH mutations from our cohort of 181 cases of genetically diagnosed Leigh/Leigh-like syndrome. Six novel HIBCH mutations were identified: c.977T&gt;G [p.Leu326Arg], c.1036G&gt;T [p.Val346Phe], c.750+1G&gt;A, c.810-2A&gt;C, c.469C&gt;T [p.Arg157*], and c.236delC [p.Pro79Leufs*5]. The Newcastle Pediatric Mitochondrial Disease Scale (NPMDS) was employed to assess disease progression and clinical outcomes. The non-invasive approach of metabolite analysis showed that levels of some were associated with clinical phenotype severity. Five (5/7) patients presented with elevated C4-OH in dried blood spots, and the level was probably correlated with the NPMDS scores during the peak disease phase. 2,3-Dihydroxy-2-methylbutyrate in urine was elevated in six (6/7) patients and elevated S-(2-caboxypropyl)cysteamine in urine was found in three patients (3/3). The median age at initial presentation was 13 months (8–18 months), and the median follow-up was 2.3 years (range 1.3–7.2 years). We summarized and compared with all reported patients with HIBCH mutations. The most prominent clinical manifestations were developmental regression/delay, hypotonia, encephalopathy, and feeding difficulties. We administered drug and dietary treatment. During follow-up, five patients responded positively to treatment with a significant decrease in NPMDS scores. Our research is the largest case series of patients with HIBCH mutations.