bluuebunny/crossref_metadata_2025_split huggingface dataset:
Creation of Highly Reducible CuO Species by High-Temperature Calcination of a Cu-Al Layered Double Hydroxide: Selective Hydrogenation of Furfural into Furfuryl Alcohol with Formic Acid
Authors: Kurniawan Enggah , Hara Takayoshi , Permana Yessi , Kojima Takashi , Ichikuni Nobuyuki , Shimazu Shogo 
Published: December 2021

Abstract
Highly reducible CuO species were created by the calcination of a Cu-Al layered double hydroxide (CuAl LDH) at 1073 K under air. After this heat treatment, the original layered double hydroxide structure was completely transformed into CuO and CuAl2O4 phases. The synthesized calcined CuAl LDH (calc-CuAl LDH) promoted the catalytic hydrogenation of furfural (FALD) into furfuryl alcohol (FOL) with formic acid (FA) as a hydrogen donor. In the initial stage of the above catalytic reaction, the CuO species in the calc-CuAl LDH matrix transformed into active Cu0 species via the formation of a Cu(HCOO)2-1,4-dioxane complex in the liquid phase. The spent catalyst was also reusable without loss of its high catalytic performance.
Ultrasound-guided core biopsy in the diagnosis of parotid neoplasia: an overview and update with a review of the literature
Authors: Hurry Katharine Julia , Karunaratne Dilhara , Westley Suzanne , Booth Alessandra , Ramesar Keith C R B , Zhang Ting Ting , Williams Michael , Howlett David C 
Published: December 2021

Objective:
Accurate diagnosis of parotid neoplasia is a key to determine the most appropriate patient management choice, including the need for surgery. This review provides an update of the literature on current practice and outcomes of parotid tissue sampling techniques, with an emphasis on ultrasound-guided core biopsy (USCB) and comparison with fine needle aspiration cytology (FNAC).

Methods:
A literature review of EMBASE, Medline, PubMed and Google Scholar was conducted.

Results:
USCB has higher sensitivity, specificity and lower non-diagnostic rates than optimized FNAC. It also has a significantly higher sensitivity for the detection of malignancy. Significant complications post-USCB are uncommon, with only one reported case of tumour seeding and no cases of permanent facial nerve dysfunction. The technique is less operator-dependent than FNAC, with less reported variation in results between institutions.

Conclusions:
USCB can be considered as the optimum tool of choice for the diagnosis of parotid neoplasia. This would particularly be the case in centres utilizing FNAC with high non-diagnostic rates or reduced diagnostic accuracy when compared to USCB published data, or in centres establishing a new service.

Advances in knowledge:
An update of the role and outcomes of USCB in the diagnosis of parotid gland pathologies.
Research shows that USCB preforms better than FNAC, in terms of sensitivity and specificity, particularly in the case of malignant neoplasia.
Complications following USCB were found to be higher than that of FNAC; however, no long-term major complications following either method have been reported in the literature.
Antioxidant effect of ethanolic extract of Pleurotus Ostreatus on 4-hydroxy-2-nonenal (HNE) and glutathione (GSH) level in lung rats exposed to cigarette smoke
Authors: Bhekti Rahimah Santun , Yuwono Soeroto Arto , Dhianawaty Djunaedi Diah , Bisri Tatang 
Published: December 2021

Background: Cigarette smoke can trigger oxidative stress. An alternative to overcome the harmful effects of cigarette smoke is through antioxidants. White oyster mushrooms (Pleurotus Ostreatus) are a source of exogenous antioxidants because many contain active compounds for potential antioxidants such as phenol and flavonoid compounds. The purpose of this study was to analyze the effect of ethanolic extract of Pleurotus ostreatus on 4-hydroxy-2-nonenal (HNE) and glutathione (GSH), as well as to analyze their correlation in the lung of Wistar male rats exposed to cigarette smoke. Methods: The study was a preclinical experiment conducted on 24 rats divided into four groups. The treatment was carried out for 42 days and antioxidant effects were assessed through levels of HNE and GSH in rat lungs. Groups were divided as follows: I- normal control, II- negative control, III and IV exposed to cigarette smoke for 60 minutes/day. Group III (treatment group) was treated with ethanolic extract of Pleurotus ostreatus at 250 mg/kg BW rat/day, and group IV (comparison group) was treated with N-acetyl cysteine 600 mg /day. Data analysis used was one-way ANOVA and Kruskal Wallis test, and Spearmen rank correlation coefficient test. Results: The results showed that the group receiving ethanolic extract of Pleurotus ostreatus had HNE levels of (44,18 ± 2,09 pg/mL) and GSH (0,04 ± 0,00 pg/mL) protein. This extract significantly increased GSH levels and inhibited the increase of HNE levels. Results of GSH (p≤0.01) showed significant results using one-way ANOVA. Conclusions: The ethanolic extract of P. ostreatus can prevent lipid peroxidation and decrease endogenous antioxidant levels in lung cells exposed to cigarette smoke. Ethanolic extract of Pleurotus ostreatus has good antioxidant potential.
Enabling transdisciplinary research: Suggestions for avoiding `road-blocks' based on a case study
Authors: Coath Martin , Mettiäinen Ilona , Contreras Roxana , Toivonen Jusu , Moore John 
Published: December 2021

In this brief plain language report we introduce a novel diagrammatic way of thinking about interactions in transdisciplinary teams. This representation is designed to provoke debate about how teams which do not share a common world view can make progress, but not necessarily direct progress, towards common goals. We further identify a range of possible problems -- which we refer to as road-blocks -- which can limit progress and reduce the effectiveness of such projects. Finally we make short suggestions about how road-blocks might be lifted. The diagrammatic representation was developed as part of the plain language notes which were kept to document the progress of a work package -- part of the Blue-Action project -- dealing with Arctic Tourism. But the report draws on wider experience of transdisciplinary working in the team and attempts an easily readable summary of some aspects of how such projects do, and do not, work. We propose that interactions between members of a team that have little in common, with respect to experience and expertise, will rarely lead to outputs that meet the goals of the project unless supplementary activities first 'recast' their views towards a common frame of reference.
Surgical treatment is not cost-effective compared to nonoperative treatment for displaced distal radius fractures in patients 65 years and over
Authors: Hassellund Sondre , Zolic-Karlsson Zinajda , Williksen John Håkon , Husby Torstein , Madsen Jan Erik , Frihagen Frede 
Published: December 2021

Aims The purpose was to compare operative treatment with a volar plate and nonoperative treatment of displaced distal radius fractures in patients aged 65 years and over in a cost-effectiveness analysis. Methods A cost-utility analysis was performed alongside a randomized controlled trial. A total of 50 patients were randomized to each group. We prospectively collected data on resource use during the first year post-fracture, and estimated costs of initial treatment, further operations, physiotherapy, home nursing, and production loss. Health-related quality of life was based on the Euro-QoL five-dimension, five-level (EQ-5D-5L) utility index, and quality-adjusted life-years (QALYs) were calculated. Results The mean QALYs were 0.05 higher in the operative group during the first 12 months (p = 0.260). The healthcare provider costs were €1,533 higher per patient in the operative group: €3,589 in the operative group and 2,056 in the nonoperative group. With a suggested willingness to pay of €27,500 per QALY there was a 45% chance for operative treatment to be cost-effective. For both groups, the main costs were related to the primary treatment. The primary surgery was the main driver of the difference between the groups. The costs related to loss of production were high in both groups, despite high rates of retirement. Retirement rate was unevenly distributed between the groups and was not included in the analysis. Conclusion Surgical treatment was not cost-effective in patients aged 65 years and older compared to nonoperative treatment of displaced distal radius fractures in a healthcare perspective. Costs related to loss of production might change this in the future if the retirement age increases. Level of evidence: II Cite this article: Bone Jt Open 2021;2(12):1027–1034.
Pemodelan Determinan Pernikahan Dini di Daerah Pedesaan dengan Pendekatan Regresi Logistik Biner
Authors: Boro Aloysius Bela , Oktora Siskarossa Ika 
Published: December 2021

<p><strong>A</strong><strong>bstract</strong><strong>.</strong> The behavior of early marriage in Indonesia is still high and most prevalent in rural areas. In addition to violating the law, a marriage performed before reaching 19 years also has many negative effects. One of them is the death of the mother and the baby. Using data from the Demographic and Health Survey 2017, this study aims to analyze the determinants of early marriages in rural areas in Indonesia. The response variable used is binary categorical data, namely the status of early marriage and not early marriage, so we use a binary logistic regression. The steps performed on this model include estimates of parameters, parameter testing either simultaneously or partially, and a test of the goodness of fit. The results show that the variables of education level, internet access, and wealth index significantly affected early marriage status in rural areas in Indonesia in 2017. Based on the goodness of fit result, this model is proper for modeling early marriage behavior in Indonesia. The study results can be used as a reference for the government in formulating policies to overcome the problem of early marriage in rural areas in Indonesia.</p><p> <strong>Keywords</strong><strong>: </strong>early marriage, rural area, categorical response variable, binary logistic regression</p>
Penerapan Metode Limited-Fluctuation Credibility dalam Menentukan Premi Murni pada Asuransi Kendaraan Bermotor di PT XYZ
Authors: Rahmah Mira Zakiah , Mutaqin Aceng Komarudin 
Published: December 2021

<p><strong>Abstract. </strong>This paper discusses the method of limited-fluctuation credibility, also known as classic credibility. Credibility theory is a technique for predicting future premium rates based on past experience data. Limited fluctuation credibility consists of two credibility, namely full credibility if Z = 1 and partial credibility if Z &lt;1. Full credibility is achieved if the amount of recent data is sufficient for prediction, whereas if the latest data is insufficient then the partial credibility approach is used. Calculations for full and partial credibility standards are used for loss measures such as frequency of claims, size of claims, aggregate losses and net premiums. The data used in this paper is secondary data recorded by the company PT. XYZ in 2014. This data contains data on the frequency of claims and the size of the policyholder's partial loss claims for motor vehicle insurance products category 4 areas 1. Based on the results of the application, the prediction of pure premiums for 2015 cannot be fully based on insurance data for 2014 because the credibility factor value is less than 1. So based on the limited-fluctuation credibility method, the prediction of pure premiums for 2015 must be based on manual values for pure premiums as well as insurance data for 2014. If manual values for pure premium is 2,000,000 rupiah, then the prediction of pure premium for 2015 is 1,849,342 rupiah.</p><p><strong>Keywords</strong><strong>: </strong>limited fluctuation credibility, full credibility, partial credibility and partial loss</p>
Sideband cavity absorption readout (SideCAR) with a robust frequency lock
Authors: Rodrigues-Machado Fernanda C. , Pestre Pauline , Dumont Vincent , Bernard Simon , Janitz Erika , Scanlon Liam , Enger Shirin A. , Childress Lilian , Sankey Jack 
Published: December 2021

We present a simple, continuous, cavity-enhanced optical absorption measurement technique based on high-bandwidth Pound-Drever-Hall (PDH) sideband locking. The technique provides a resonant amplitude quadrature readout that can be mapped onto the cavity’s internal loss rate and is naturally compatible with weak probe beams. With a proof-of-concept 5-cm-long Fabry-Perot cavity, we measure an absorption sensitivity

∼

10

−
10

cm

−
1

/

Hz

from 30 kHz to 1 MHz, and a minimum value of

6.6
×

10

−
11

cm

−
1

/

Hz

at 100 kHz, with 38 µW collected from the cavity’s circulating power.
Tuschenanalyse im P 11702
Authors: Nehring Grzegorz , Krutzsch Myriam , Rabin Ira 
Published: December 2021

Abstract
Near-infrared reflectography and imaging X-ray fluorescence analysis reveal that carbon inks of two different compositions were used in the papyrus manuscript Berlin P 11702. In contrast with the writing ink, one of the carbon drawing inks contained a significant addition of iron. This result emphasizes the need for routine instrumental ink analysis.
Establishment of the New Zealand white rabbit animal model of fatty keratopathy associated with corneal neovascularization
Authors: Gao Yikui , Li Cong , Li Xiaoyun , Zhang Minghong 
Published: December 2021

Abstract
The term fatty keratopathy is used to describe the phenomenon of fat deposition caused by corneal neovascularization, which will severely affect the eye’s beauty and vision. The purpose of this study was to establish a New Zealand white rabbit animal model of fatty keratopathy, that is, the establishment of an animal model of fatty keratopathy. The goal was achieved by the combination of a corneal neovascularization animal model and a hyperlipidemia animal model. Two groups were created according to the experimental sequence. The first group initially induced a corneal neovascularization pattern and later induced a hyperlipidemia pattern, and the second group followed the opposite sequence. The results of the two groups showed that all the significant crystalline deposits of the cornea were visible. So the animal models of fatty keratopathy were successfully established in both groups.
Predicting drug–drug interactions by electrochemically driven cytochrome P450 3A4 reactions
Authors: Shumyantseva Victoria V. , Koroleva Polina I. , Bulko Tatiana V. , Sergeev Gennady V. , Usanov Sergei A. 
Published: December 2021

Abstract

Objectives
Human cytochrome P450 3A4 is the most abundant hepatic and intestinal Phase I enzyme that metabolizes approximately 60% marketed drugs. Simultaneous administration of several drugs may result in appearance of drug–drug interaction. Due to the great interest in the combination therapy, the exploration of the role of drug as “perpetrator” or “victim” is important task in pharmacology. In this work the model systems based on electrochemically driven cytochrome P450 3A4 for the analysis of drug combinations was used. We have shown that the analysis of electrochemical parameters of cytochrome P450 3A4 and especially, potential of the start of catalysis, Eonset, possess predictive properties in the determination of the leading (“perpetrator”) properties of drug. Based on these experimental data, we concluded, that the more positive potential of the start of catalysis, Eonset, the more pronounced the role of drug as leading medication.

Methods
Electrochemically driven cytochrome P450 3A4 was used as probe and measuring tool for the estimation of the role of interacting drugs.

Results
It is shown that the electrochemical non-invasive model systems for monitoring the catalytic activity of cytochrome P450 3A4 can be used as prognostic devise in assessment of drug/drug interacting medications.

Conclusions
Cytochrome P450 3A4 activity was studied in electrochemically driven system. Method was implemented to monitor drug/drug interactions. Based on the obtained experimental data, we can conclude that electrochemical parameter such as potential of onset of catalysis, Eonset, has predictive efficiency in assessment of drug/drug interacting medications in the case of the co-administration.
Modifying effects of TNF-α, IL-6 and VDR genes on the development risk and the course of COVID-19. Pilot study
Authors: Fishchuk Liliia , Rossokha Zoia , Pokhylko Valeriy , Cherniavska Yuliia , Tsvirenko Svitlana , Kovtun Serhii , Medvedieva Nataliia , Vershyhora Viktoriia , Gorovenko Nataliia 
Published: December 2021

Abstract

Objectives
COVID-19 continues to range around the world and set morbidity and mortality antirecords. Determining the role of genetic factors in the development of COVID-19 may contribute to the understanding of the pathogenetic mechanisms that lead to the development of complications and fatalities in this disease. The aim of our study was to analyze the effect of TNF-α (rs1800629), IL-6 (rs1800795) and VDR (rs731236 and rs1544410) genes variants on the development risk and the course of COVID-19 in intensive care patients.

Methods
The study group included 31 patients with diagnosis “viral COVID-19 pneumonia”. All patients underwent standard daily repeated clinical, instrumental and laboratory examinations. Determination of IL-6, TNF-α, and VDR genes variants was performed using the PCR-RFLP method.

Results
It was found a significant increase in the rate of the CC genotype and C allele (38.7 vs. 12.0% and 0.6 vs. 0.4%, respectively) of the IL-6 gene in all patients of the study in comparison with population frequencies. There was a significantly higher rate of heterozygous genotypes TC and GA of the VDR gene in group of died patients. The rs1800629 variant of the TNF-α gene is associated with the need for respiratory support and its longer duration in patients with COVID-19.

Conclusions
The obtained results support a hypothesis about the influence of variants of IL-6, TNF-α and VDR genes on severity of COVID-19. However, in order to draw definite conclusions, further multifaceted research in this area are need.
A Systematic Literature Review and Meta-Analysis of Entrepreneurial Personality
Authors: Howard Matt C. , Boudreaux Melanie 
Published: December 2021

Abstract
Entrepreneurial Personality (EP) is a collection of personality traits that broadly and strongly relate to entrepreneurial outcomes across most contexts. The goal of the current article is to address present uncertainties surrounding EP by identifying its dimensions and assessing their relations with entrepreneurial outcomes. Our systematic literature review demonstrates that seven dimensions are commonly used to represent EP: innovativeness, risk-taking, achievement orientation, locus of control, proactiveness, self-efficacy, and autonomy orientation. Via meta-analytic structural equation modeling, we find support for a one-factor model composed of these seven dimensions, suggesting that they indeed represent a unitary construct. Our meta-analysis also supports that EP and its dimensions consistently produce significant relations with entrepreneurial attitudes, intent, status, and performance. EP is thereby supported as an important component of successful entrepreneurial endeavors, and our meta-analytic results provide clear criteria for determining the inclusion of dimensions within the construct of EP – which our seven identified dimensions satisfy.
Trends in the St. John’s wort (Hypericum perforatum) research literature: a bibliometric analysis
Authors: Ng Jeremy Y. 
Published: December 2021

Abstract

Objectives
St. John’s wort (Hypericum perforatum) has been used in traditional medicine for centuries for different conditions, including kidney and lung ailments, insomnia, depression, and to aid wound healing. The objective of the present bibliometric analysis is to capture the characteristics of research publications on the topic of St. John’s wort.

Methods
Searches were run on April 09, 2021, and results were exported on the same day to prevent discrepancies between daily database updates. Trends associated with this subset of publications were identified and presented. Bibliometric networks were constructed and visualized using the software tool VOSviewer.

Results
A total of 1,970 publications were published by 5,849 authors across 961 journals from 1859 to 2021. Beginning in the late 1990s, a steep increase was found in the volume of publication on this topic. The journal that published the largest number of publications was Phytotherapy Research. The most productive countries included Germany and the United States.

Conclusions
The present study provides the characteristics of the St. John’s wort literature that allows understanding of the past, present, and future of research in this area. It is a useful evidence-based framework on which to base future research actions and academic directions.
NOMEN PROPRIUM UND METONYMIE
Authors: Rubáš Michal 
Published: December 2021

Abstract
When language change phenomena have repercussions in various social areas at the same time, they are worth an analysis. One of the well documented occurrences of this kind is the discursive history of the metonymic proper name Bologna as a designation of an education reform. As Johannes Angermüller und Ronny Scholz stated in their remarkable study (2013), its mere introduction had made some political processes easier. In this paper the question is put whether some distinctions of the notable metonymy theory by Peter Koch (2004) are able to deliver categories to clarify this phenomenon. In doing so, I point out some deficiencies of Kochs approach concerning his conception of metonymy as such and demonstrate that these are to be ascribed to its “cognitive” frame and that the remedy lies implicitly in an elementary consideration by Saussure and in an explicit passage by Husserl whom Koch himself invokes. As a result of this, I come to the conclusion that Saussure and, particularly, Husserl could have elucidated the most crucial feature of the metonymic proper name more appropriately.
Traducción feminista transnacional: instrumentalización y manipulación de la recepción transnacional del relato autobiográfico sobre violencia sexual
Authors: Montes Antonia 
Published: December 2021

Abstract
Transnational feminist translation studies stand for activism, cooperation and solidarity in connecting feminist thinking developed in all parts of the world (Alvarez et al. 2014, Castro/Ergun 2017, Flotow/ Farahzad 2017, Flotow 2019). One of the important issues is wartime sexual violence, which is the focus of this article, and constitutes a feminist, transnational phenomenon. The account of wartime sexual violence by female victims faces instrumentalization and manipulation by the agents involved in the publication process, including the translators, who are an active part of the patriarchal literary system, with the purpose “to make them fit in with the dominant, or one of the dominant ideological and poetical currents of their time” (Lefevere 1992: 8). The transnational reception, thus, is driven by ideological and commercial interests that agents in a literary system negotiate. The aim of this article is to analyse the transnational reception process, examined under the perspective of transnational feminist translation, and based on questions as who rewrites and how is the wartime sexual violence account rewritten. Undertaking a case study, the diary ‘Eine Fau in Berlin’ of an anonymous female author, Anonyma, who describes rape, prostitution and the gender relations in the context of Second World War, an analytical framework is developed to shed light on the question how women’s writing on wartime sexual violence and its transnational reception are determined by mechanisms of instrumentalization and manipulation that are due to the conceptions and moral values that prevail over wartime sexual violence in two different political and historical eras. We conclude that transnational feminist translation enables activism and solidarity about wartime sexual violence beyond geographical limitations. This leads to the empowerment of the victims on a transnational level.