bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on Nano Graphene Oxide Used to Enhance the Stability of Emulsion
Authors: Wang Daming , Chen Hong 
Published: March 2021

Abstract
Graphene oxide is prepared by carbonization, and then the graphene oxide is grafted with dodecylamine by one step to adjust the wettability. XRD and optical pattern tests of graphene oxide showed that the process of grafting dodecylamine modification can expand the layer spacing of graphene oxide by 0.044nm and enhance the intensity of fluorescence. The grafting dodecylamine modification can significantly change the solubility and wettability of graphene oxide in water, and the contact angle of the modified graphene oxide with water is 165°. Modified graphene oxide can effectively enhance the stability of emulsions stabilized by SDBS surfactants.
Discovery of Novel Mammalian target of rapamycin (mTOR) Inhibitors by Support Vector Machine
Authors: Wang Panpan , Xu Xiaobo , Li Yinghong , Li Bo , Pei Qinglan , Yu Pei , Jing Chenxi , Lu Meng 
Published: March 2021

Abstract
Mammalian target of rapamycin (mTOR) is a protein serine/threonine kinase playing the central downstream role in multiple mitogenic signalling pathways. As a c entral regulator of cell growth, proliferation, differentiation and survival, mTOR has b een reported to modulate proliferation and angiogenesis in neoplastic processes. Curre ntly, sirolimus and its analogues the only five mTOR inhibitors approved for clinical u se, which shows a great capacity in anticancer therapy. However, endocrine resistance in cancer therapy has been observed in sirolimus analogues, and the unavailability of n ew mTOR inhibitor besides similar structure of sirolimus analogues makes the resistan ce even worse. It is urgent to discovery new mTOR inhibitors as candidates for develo pment of effective anticancer drugs. In this study, support vector machine (SVM) as a virtual screening strategy was proposed. SVM models of mTOR inhibitors were constr ucted by training data published before 2012, and the ones published after 2012 as test set were used to verify according to cross validation. The selected model performed thi n false hit rates of 0.12% and 0.46% by screening PubChem and MDDR chemical libr aries respectively. As results, 9 novel novel scaffolds for mTOR were identified, and 6 of them have been reported their anticancer-related therapeutic capacity. In summary, SVM performed its ability to identify novel mTOR inhibitors, which can supply some candidates for mTOR anticancer drugs, and supply effective method for anticancer dru g discovery in future.
The Application of Cloud Class in the Teaching of Biochemistry
Authors: Sun Naxin , Wang Yuanxiu , Liu Yuehui 
Published: March 2021

Abstract
Interactive cloud class platform assisted instruction is an important supplement of classroom teaching, and it is becoming one of the important forms of new teaching methods. Biochemistry is the most important specialized basic course for biotechnology students, and it is also considered one of the hardest subjects among the curriculum. The current work explores the application of the cloud class in the teaching of the theoretical biochemistry courses. Practical research shows that the application of the cloud class teaching platform can effectively motivate students’ learning potential to the greatest extent. With this tool, teachers and students have come to get keenly a sense of the kind of creativity and advancement of information-based teaching, and the blended learning integrated face-to-face instruction and online teaching provides a new way and method in higher education teaching reforming.
Research and Practice on Training Mode Reform of Applied Talents in Environmental Engineering Technology under Industry-Teaching Integration Training Base
Authors: Zhou Xiaonan , Li Chunying , Wang Chuanjie , Luo Dan 
Published: March 2021

Abstract
It is an effective way to promote the in-depth development of school-enterprise cooperation to build a high-level professional training base integrating industry and education with radiation-leading effect [1]. It is an important measure to reform the training mode of talents and improve the training ability of talents with technical skills. Through the research on the construction and teaching reform of the industry-teaching integration training base for environmental engineering technology major in Chongqing vocational college of resources and environmental protection, adopt the “four-in-one” teaching reform mode of “Internet + teaching + project +X certificate” [2], carry out reform and practice of application-oriented talent training mode based on industry-teaching integration training base. Implement the curriculum teaching design that emphasizes vocational competence [3], analyze the results and experience, put forward the problems existing in the process of educational reform and the effective operation thinking of sustainable development, to study and explore a new path for the trainning of environmental engineering talents under the background of industry-education integration training base [4], continuously enhance the ability of environmental engineering technology specialty to accurately serve regional development needs.
Effects of Anaerobic Digestion on Antibiotic Resistance Genes in Sludge
Authors: Zhang Xin , Wang Na 
Published: March 2021

Abstract
Sludge treatment and reuse in municipal sewage treatment plants is beneficial to improve economic effect and reduce environmental pollution. Sludge is an important source of contamination of antibiotic resistance genes. Anaerobic fermentation is an important way to treat activated sludge. Effective treatment of municipal sludge can avoid the release of pathogenic microorganisms and resistance genes (ARGs) into the environment and cause secondary pollution. The research results will be of certain guiding significance to the resource utilization of sludge.
Summary and Prospect of Research on Agricultural Non-point Source Pollution in my country’s Watershed
Authors: Xiong Guobao , Ma Yiming , Luo Yuanda 
Published: March 2021

Abstract
Agricultural non-point source pollution poses a serious threat to the quality of water environment in river basins, which has attracted more and more attention from the government, society and academic circles. With the increasingly prominent problem of agricultural non-point source pollution in river basins in China in recent years, domestic scholars have carried out extensive research on it. However, most of them are case studies on a single watershed, and there is a lack of overall grasp on agricultural non-point source pollution in the watershed at present in China. In view of this, this paper sorts out and analyzes the existing research results from the related concepts, characteristics, formation mechanism, measurement methods and other aspects of agricultural non-point source pollution, in order to try to sum up the general laws from the current individual research, and on this basis, puts forward the direction that future research can explore, providing ideas and reference for researchers and practitioners of agricultural non-point source pollution in river basins of China.
Effect of Gas Liquid Two Phase Flow on VOCs Degradation by Atmospheric Low Temperature Plasma
Authors: Liu ChangLin , Ren Xi , Zeng MingHui 
Published: March 2021

Abstract
This paper proposes a combination of barrier dielectric discharge (DBD) and saturated sodium bicarbonate solution boiling tube to generate a gas-liquid two-phase flow containing plasma, and through characterization methods to study the solution in the boiling tube under the action of DBD discharge the law of boiling evolution. Then, by designing the cavity, the gas-liquid two-phase flow mixture produced by the boiling tube was sprayed into the needle electrode discharge area of the reaction chamber, and the influence of the gas-liquid two-phase flow on the plasma treatment of VOCs was explored. Spectral diagnosis proved that after the introduction of gas-liquid two-phase flow, the plasma concentration in the discharge area increased significantly, and the removal rate of VOCs was effectively increased from 32% to 55% in the decontamination experiment. It is proved that the introduction of gas-liquid two-phase flow can improve the effect of plasma degradation of VOCs.
Functionalized Selenium-Doped Carbon Quantum Dots for Targeting Detection of Reactive Oxygen Species in Live Cells
Authors: Zhou Danling , Huang Hong , Wang Yan , Yu Junrong , Hu Zuming 
Published: March 2021

Abstract
Selenium doped carbon quantum dots (Se-CQDs) are synthesized by a facile hydrothermal process. The Se-CQDs show narrow size distribution in the range of 3-4 nm, good optical properties, and high sensitivity in detection of various reactive oxygen species (ROS) as revealed by several characterizations. The Se-CQDs are then modified by three kinds of organelle targeting molecules with the aim of targeting detection of ROS in specific organelles. The confocal fluorescence studies on modified Se-CQDs and commercial organelle marker demonstrate the successful targeting detection of ROS in different organelles by our specific modified Se-CQDs.
Experimental study on the strain self-sensing properties of nano carbon black modified resin based CFRP bars
Authors: Liu Dan , Liu Ronggui , Zhang Shaofeng 
Published: March 2021

Abstract
In order to explore the influence of nano carbon black content on the piezoresistive effect of resin based CFRP bars, 2%, 4%, 6%, 8%, 10% nano carbon black modified resin were used as matrix, and the roller extrusion process was adopted to prepare CFRP bars. The initial resistivity, the response of resistance change and the relationship between sensitivity change and strain under static tensile test were compared and analyzed. The results show that the strain sensitivity of CFRP bars can be significantly improved, and the discreteness of test data can be reduced by adding uniformly dispersed carbon black into the resin matrix. The optimum content of carbon black is 6%, the sensitivity is 25.4 in the strain range of 0 ∼ 1.2%, and the linear relationship between resistance change rate and strain is satisfied, and the determinable coefficient is 0.985. When the content of carbon black is more than 6%, the effect of modification on the sensing properties of CFRP bars is not obvious.
Analysis of microstructure and wear resistance of NM400 thick plate
Authors: Cong Liang , Pei Yingchao , Xia Dianxiu , Wang Dongyue , Han Zhengpeng , Han Qing , Liu Zhiheng , Guo Yu 
Published: March 2021

Abstract
The hardness distribution and microstructure morphology of NM400 low alloy wear resistant steel plate with thickness of 50mm and 60mm were tested and analyzed, and the sliding wear performance of typical measuring points was also analyzed. The results show that the depth of the NM400 (50mm) hardening layer is about 35mm, accounting for about 70% of the plate thickness. The depth of the NM400 (60mm) hardening layer is about 22mm, accounting for about 37% of the plate thickness. With the position of the measuring point gradually away from the surface of the steel plate, the martensite content in the microstructure of NM400 (50mm) and NM400 (60mm) gradually decreased, and the contents of pearlite, bainite and other microstructure gradually increased. The hardness of NM400 (50mm) gradually decreased from 410HV to 335HV, and the hardness of NM400 (60mm) gradually decreased from 410HV to 305HV. The micro-wear morphologies of NM400 (50mm) and NM400 (60mm) at each measuring point are mainly furrow and contact fatigue spalling, and the wear types are mainly abrasive wear and contact fatigue wear. The furrow depth and the number of furrows on the worn surface of the sample at the corresponding measuring point position gradually increased as the measuring point position moved away from the steel plate surface, and the spalling area and the depth of the spalling pit gradually increased. The wear type gradually changed from particle wear to contact fatigue wear.
Study on the influence of the variation of PM2.5 index of gaseous pollutants on human health in Gansu Plateau in recent years
Authors: Gao Jike 
Published: March 2021

Abstract
In recent years, the party and the country to environmental governance as a new era of socialism with Chinese characteristics of the basic guarantee of the development of various undertakings, clean air is a necessary condition for human health survival, quality air quality is a beautiful livable important indicator. The diurnal, monthly and annual changes of PM2.5 in Gansu Plateau in recent years were tracked and analyzed by means of instrument measurement and mathematical statistics. Based on the analysis of the data model, the promotion strategies are put forward from the perspective of human health.
Comparison of Performance and Microstructure of Two Kinds of Cold Spray Anticorrosion Composite Coatings on High-strength Steel
Authors: Shi Zhongchuan 
Published: March 2021

Abstract
Objective to study the performance of Zn/Ni composite coatings and Al/Zn composite coatings, which were deposited by Cold Gas Dynamic Spray. Methods: Those coatings was sprayed by Zn and Ni mixture powder and Al and Zn mixture powder on 300M high-strength steel surface, the SEM images and micro hardness tester analyzed the two kinds coatings’ morphology and microstructure. The corrosion resistance of Zn/Ni coatings can be compare with Al/Zn coatings, which was investigated by neutral salt-spray test and coating furcated test. Results The results indicate that Zn/Ni coatings porosity is 0.8%, it is same as Al/Zn coatings. The micro hardness of Zn/Ni coatings is 70.8HV, which is higher than Al/Zn coatings 61.2HV. However, the salt spray result of Al/Zn coatings can reach 1000h and it can reach 770h even the coatings fails; which is better than Zn/Ni coatings, their salt spray resistance can reach 770h and it can reach 350h when the coatings fails. Conclusion those coatings could both be efficient corrosion resistance coatings on 300M high strength steel surfaces.
Integrated Device for Collection of Garden Waste and Production of Auricularia Auricula Medium
Authors: Shao Xinzhe , Wang Jiawen , Cao Xuewei , Yan Zhen , Zhao Bingjie , Lv Yifan , Li Yiwei 
Published: March 2021

Abstract
With the acceleration of greening process in China, the output of garden greening waste is also increasing, but the treatment method of greening waste is single and the utilization degree of resources is low. Therefore, this work puts forward a method that integrates waste collection and Auricularia auricula culture medium production. Taking garden waste as raw material, the original material of Auricularia auricula culture medium is obtained through the process of collection, primary crushing and secondary crushing, and mixing ratio process. After simple packaging and subsequent sterilization and disinfection process, the regenerated Auricularia auricula culture medium is made.
A Study on Current Situation of Cycling along Sichuan-Tibet Line
Authors: Geng Shuai , Zhou Xin 
Published: March 2021

Abstract
This paper takes Sichuan-Tibet Line cyclists as the research object, and adopts the methods of literature review, field investigation and questionnaire investigation to study the current situation of Sichuan-Tibet Line cyclists. Research results: Most of them are men, while women are on the rise. The age structure is jujube pit-shaped, with young people aged 18-25 accounting for the majority. It is widely sourced from east and southwest China, and other regions also account for a certain proportion. There are many students, and college and undergraduate education is the main body. The income is in the middle and upper levels, and the income is stable. They decided to ride with a variety of motives, traveling with friends, and most of them chose to ride from July to August. The Sichuan-Tibet Line is characterized by large ups and downs, poor road conditions, complicated and changeable weather and frequent geological disasters. It has a long riding distance, few people along the way, few supply points, few cycling events, and the government does not attach great importance to it. The purpose of this paper is to improve the influence of Sichuan-Tibet Line, bring sports tourism benefits along the Sichuan-Tibet Line, and realize the win-win policy of “sports + tourism”
Numerical Simulation for the Flow Characteristics of Shale Oil in Fractured Shale Reservoirs
Authors: Peng Fei , Huang Zhaoqin 
Published: March 2021

Abstract
Compared to conventional reservoirs, shale reservoirs are characterize by the extraordinary low porosity and permeability, which contribute to the large-scale application of the technology of hydraulic fracturing in the development. The flow characteristics of shale oil is quite complicated in the hydraulic and natural fractures and the flow characteristics of shale oil in fractures is vital significant to oilfield development. In this paper, a model is developed to simulate the flow characteristics in fractured shale reservoirs, which fully coupling the geomechanics and fluid flow. Specifically, an embedded discrete fracture model is adopted to characterize the hydraulic fractures and the flow between natural and hydraulic fractures. Correspondingly, the Multiple Interacting Continua model is adopted to characterize the flow between matrix and natural fractures. The influence on production caused by the stress sensitivity of two kinds of fractures is considered. Then, the sequential iterative solution method is adopted to solve the model which coupled the geomechanics and fluid flow, and the finite volume method and the finite element method are applied to solve the fluid-governing equations and geomechanics-governing equations, respectively.
Modeling and Analysis of Ferrofluid Transport in Porous Media
Authors: Li Yuan , Yao Jun , Huang Tao 
Published: March 2021

Abstract
As a new kind of material, ferrofluid has received a huge amount of concern and researchers have tried to apply ferrofluid in the field of petroleum engineering. In this paper, the effect of polymer in ferrofluid has been taken into consideration in ferrofluid flooding, a comprehensive mathematical model has been developed. The mathematical model considers the magnetic force, the physical process of the mobilization of polymer through porous media. The results show that using ferrofluid as displacing fluid can greatly improve oil recovery.
Geophysical characteristics and interpretation methods of the buried hill surface in the west slope of Shulu depression
Authors: Ren Chongyu , Lv Hongjiu , Huang Wenfeng , Liu Bo , Zhao Zhengquan 
Published: March 2021

Abstract
In the cause of the buried hill and conglomerate layer are carbonate rock type, there is no obvious difference between the wave impedance and the overlying strata. Therefor there is no strong reflection on the surface of the buried hill, and no obvious change in the logging curve. In order to solve this problem, taking west slope of Shulu depression as an example, the logging characteristics of the conglomerate surface and seismic reflection characteristics of the buried hill surface are summarized. The sedimentological characteristics of the buried hill surface are analyzed. The differences between the identification of the buried hill surface and the identification of the conglomerate surface are found. The interpretation method of the buried hill surface is defined. It provides a theoretical basis for better interpretation of buried hill reservoir.
Research on Population Spatialization Method Based on AWA-ESPCN
Authors: You Peng , Liu Minghao , Du Jiang , Jing Lei 
Published: March 2021

Abstract
The spatialization of population is the process of rasterizing demographic data, which is of great significance for government decision-making and promoting the coordinated and sustainable development of social economy, resources and environment. In the continuous research of multiple linear regression, spatial interpolation, the use of multi-source heterogeneous data, random forest and other methods, a batch of highly representative global and national-scale population spatial databases have been born. Therefore, through the super-resolution of deep learning the method is more valuable for population low-scale sampling research and end-to-end mapping to achieve high-precision downscaling and enhance the robustness and generalization of the training model. This paper is based on the population statistics of the counties in Chongqing municipality in 2010, through the area-weighted rasterization coupled sub-pixel convolutional neural network (ESPCN) to learn the global and local features of the population to achieve 500m resolution population spatialization, and compare it with the other 2 compare plan. The results show that the training model using this method has the lowest mean square error, the smallest residual interval, and the best picture effect.
Effect of Adding Different Proportions of Arsenic on the Carbon Content of Sandy Soil
Authors: Cao Tingting , Guo Zhen , Xu Yan 
Published: March 2021

Abstract
In order to explore the effect of different proportions of arsenic sandstone on the carbon content of sandy soil, the total organic carbon index of arsenic sandstone and sand composite soil was selected for analysis. The carbon content is the highest, especially in the 0-20cm soil layer. After 9 years of cultivation, the 0-10cm total organic carbon content of each proportion of the composite soil layer is significantly higher than that of the sandy land. The average total organic carbon of 9 years of cultivation Compared with three years of cultivation, it has increased by 68.50%, which is a significant increase. In the early stage of compounding, due to engineering disturbances and disturbance of the natural cultivation process of the soil, the total organic carbon content in the compounded soil has a downward trend. With the later cultivation of the compounded soil, the total organic carbon increased significantly, and the addition of arsenic was greatly increased. This accelerated the natural succession process of sandy soil.
Research Progress of Soil Microorganism Application Based on High-Throughput Sequencing Technology
Authors: Zhang Yujun , Wang Puchang , Long Zhongfu , Ding Leilei , Zhang Wen , Tang Huajiang , Liu Jiajia 
Published: March 2021

Abstract
Soil microorganisms play the role of decomposers and consumers in the ecosystem, and microbial diversity can reflect soil characteristics to a certain extent. The research on soil microbial diversity mainly includes the following four aspects: species diversity, structural diversity, functional diversity and genetic diversity. In the past, due to the limitation of technology and other reasons, the traditional methods to study soil microorganisms were too simple to fully reflect the structure of soil microbial community. At present, the second generation of sequencing technology, high-throughput sequencing, is favored by researchers because of its high integrity and accuracy, and has become one of the main methods to study soil microorganisms.
Research on Information Platform of Plate Cutting and Groove Workshop
Authors: Zhang Teng 
Published: March 2021

Abstract
With the state’s policy support and encouragement for the transformation and upgrading of high-end equipment manufacturing industry, as well as the maturity of technologies such as big data and artificial intelligence, intelligent production is gradually developing towards systematization and platform. At present, none of the large-scale plate blanking workshops have realized digital production. The blanking workshop is the source of manufacturing production, and the digitalization of the blanking workshop is very important for the production management of enterprises. The digital transformation of blanking workshop is gradually extended to other workshops, which greatly improves the intelligent level of manufacturing industry. This paper briefly describes the method of realizing the digitization and informatization of the blanking workshop, and further improves the intelligent degree of production through the construction of the workshop informatization platform, so as to improve the work efficiency of the workshop.