bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of probiotic bacterial concentrate technology and practical aspects of its use
Authors: Куксова Елена Владимировна , Волкова Галина Сергеевна , Серба Елена Михайловна 
Published: September 2021

В статье приводятся результаты разработки технологии получения биоконцентрата на основе многоштаммового консорциума молочнокислых и пропионовокислых бактерий, который может использоваться для силосования зеленых кормов. Установлены параметры ферментации, стадии концентрирования, дана качественная характеристика готового продукта.
The article presents the results of the development of the technology of producing bioconcentrate on the basis of multistrain consortium of lactic acid and propionic acid bacteria which can be used for ensilaging green forages. The fermentation parameters, concentration stages, and qualitative characteristics of the finished product are established.
INVERSION OF GRAVITY DATA USING A GENETIC ALGORITHM
Authors: GRYSHCHUK Pavlo 
Published: September 2021

The genetic algorithm for the selection of gravitational sources is considered. In the basis of the approach, the principle of selection of genes from fathers and mutations was laid down, which was adapted to form geological structures. For a two-dimensional grid model, the designation of apparent density in the blocks is selected by a choice of models of two (parental) variants, in which gravitational initial and calculated anomalies coincide better. In the quality of the object function is used a middle gradient norm of gravity fields. Generation of new models for effective density in blocks is released randomly. Theoretical models were built up for one body with one and two values of apparent densities.
The theoretical sections with four layers were considered. The fitting of the model was carried out under the condition that the value of the effective density was known or a certain range was set. Each block was rectangular in shape with a square section in the plane of the gravity data profile and a limited lateral elongation. Comparison of the output and calculated anomalies of the gravitational acceleration was carried out using the average norm and the percentage error. The absence of jumps in the objective function graph ensured that an accurate model was determined. The correct geometry of a body with a homogeneous apparent density was determined at a fixed value of the effective density for four layers.
The model with two values of density had some errors in determining the geometry of the bodies. The genetic algorithm, based on an evolutionary approach to certain physical parameters of blocks, performs the fitting of a gravity model rather quickly and effectively. The main factors affecting the accuracy of geometry are apparent density data. The implemented approach allows one to estimate the cross section by the grid distribution of the effective density. The development is applied for a two-dimensional interpretation of the gravity anomaly over an oil and gas field. The resulting interpretation of the shape of the anticlinal structure is consistent with geological data.
DRILLING OF COMPLEXES WITH HYDRAULIC TRANSPORT OF A CORE FOR INCREASE OF EFFICIENCY OF GEOLOGICAL EXPLORATION WORKS
Authors: VDOVYCHENKO Anatolii 
Published: September 2021

On the basis of an in-depth analysis of domestic achievements and the results of experimental and methodological works and practice the expediency of widespread use of improved technical means and technologies for drilling geological exploration wells with complexes counterflush coring (CCD) till the depth of 300 m upon sedimentary strata is substantiated. During the exploration of brown coal deposits and titanium placers, which convincingly confirm the high efficiency of CCD with appropriate modifi cations of equipment, technology and testing methods for specific productive horizons and host rocks. The best results of industrial application of CCD were obtained during the exploration of the Paromivske ilmenite placer deposit (2016). High technical and economic indicators of completion of work in difficult socio-economic and geological and technical conditions were achieved thanks to CCD application.
The main argument in favor of CCD is undoubtedly proven by ultra-high productivity with a significant reduction in cost and improved quality of the work. The operational geological informational content of the method allows timely adjustments and responsibly choose the most optimal flexible schemes and methods of geological research. Due to the significantly reduced timing of drilling operations, field research can be carried out shorter at the most favorable climatic conditions and seasons of agricultural activity. The mobile circulation system excludes the construction of earthen sedimentation tanks, which signifi cantly reduces the size of disturbed soils, their contamination and prevents the loss of flushing fluid. The peculiarities of the technology and organization of work promote close cooperation, mutual control and understanding of technical, geological, geophysical and other personnel serving and actively mobilize for high-quality and highly efficient performance of geological tasks. A reduction of heavy operations in the technological process significantly improves the working conditions for the service personnel, increases the production culture, and contributes to the attractiveness of the drilling profession.
Ukraine has sufficient production facilities (at Kiev Drilling Equipment Plant, Dnepropetrovsk Drilling Equipment Plant, Discovery - Drilling Equipment. Ukraine LLC, etc.), which are capable of providing geological exploration companies with modern CCD.
The main reasons that hinder the development of modern highly efficient geological exploration technologies are recognized and the optimal ways to solve the problem of widespread introduction of CCD are featured.
Contributions to improve sustainability conditions in gemstonebenefiting companies
Authors: Sindelar Fernanda Cristina Wiebusch , Barden Júlia Elisabete , Stülp Simone 
Published: September 2021

The gemstones and jewels production chain have been an important source of income and job creation in several regions of Brazil. However, sometimes, its activities haven’t been developed in an environmentally correct and sustainable context. In this sense, this work seeks to investigate indicators, to propose a framework of indicators to evaluate and monitor the sustainability conditions of companies that process gemstones. Therefore, a proposal was prepared considering the specificities of the sector, containing 10 indicators and 24 variables distributed in the environmental, economic, social, and technological dimensions. The proposal was verified empirically with a company, a case study, located in Teutônia/RS, which presents the main characteristics of the companies belonging to the sector. The use of the framework of indicators provided information on the company’s sustainability conditions, identifying positive aspects and also those that need to be improved to assist in the search for a more sustainable management of activities. On the other hand, the results achieved present information that can serve as a reference for comparison with other companies in the sector, as well as assist in the decisionmaking process in search of more sustainable conditions.
Expansion of Cashew Cultivation and its Environmental and Economic Impacts on Guinea-Bissau
Authors: Seca Abdulai Ismail , Pereira Henrique dos Santos , Silva Suzy Cristina Predroza da 
Published: September 2021

Guinea-Bissau has recently become the fifth largest producer in the world of Cashew Nut Shell (CNS) and the product accounts for 90% of the country’s total exports. The objective of this study was to analyze the expansion of cashew cultivation and its environmental and economic impacts on the country, from the perspective of sustainable development. In the methodology, correlational statistical analyses were used, based on multiple regression, correlation, and linear regression techniques. To qualify the empirical results based on the historical series of secondary data, an online questionnaire was applied to nine experts to assess the impacts of sector-specific public policies on Cashew Nut Shell Production (CNSP) and Cashew Nut Shell Export (CNSE). Finally, geoprocessing techniques were used to identify the deforestation trends in the country (2002-2018). As main results, it was verified that from 2000 to 2015, the CNSE accounted for an average of 8.9% of the country’s GDP. As for environmental impacts, it was found that between 2002 and 2012, the country’s deforestation was explained by the CNSP (p < 0.001 and R² = 0.91), whereas between 2013 and 2017, although positively associated, the relationship was not significant. Geoprocessed data on vegetation cover indicate that from 2002 to 2018, accumulated deforestation was intensified mainly in the southern and northern regions of the country. To make full use of cashew, a greater effort is needed from the Government and the productive sectors, which would allow the sustainable development of the sector and a substantial increase in the production of other crops.
Pharmacovigilance- A drug safety monitoring tool
Authors: Chauhan Shivangi 
Published: September 2021

The objective of this narrative review is to converse about drug safety, global
pharmacological authorities and their responsibility, the process of adverse event
reporting, and the main functions of pharmacovigilance. Pharmacovigilance is a science
that ensures patient safety against both newly launched and well-established medicinal
products in the market. Pharmacovigilance is considered a specific tool used for observing
and estimating Adverse Drug Reactions (ADRs) and is essential for successful drug
management programs, clinical trials, and public health programs. In the few past years,
the number of reported ADRs got increased as a result of which the volume of data got
increased. To handle such huge data and the need to understand the pharmacovigilance, it
requires highly skilled and proficient people for immediate detection of drug's side effects
and protects the product from improper removal. The existing global network of
pharmacovigilance centers will be strengthened through an independent review process in
coordination with the Uppsala Monitoring Center. Its main role is to assess trials and
crucial issues of drug safety that probably influence public health beyond national
borders. In this global arena, Pharmacovigilance becomes an important and integral part
of clinical research. Most of the countries set up pharmacovigilance centers to monitor
drug safety; however, millennial pharmacovigilance faces major challenges for improved
safety and drug monitoring.
ANALISIS PELAKSANAAN PEMUNGUTAN BEA PEROLEHAN HAK ATAS TANAH DAN BANGUNAN DI KOTA TOMOHON
Authors: Tiwow Sesilia , Ohy Juliana , Hermanto Bambang 
Published: September 2021

Abstrak
Penelitian ini bertujuan untuk mengetahui bagaimana pelaksanaan pemungutan BPHTB di Kota Tomohon. Penelitian ini menggunakan metode deskriptif eksploratif dengan pendekatan kualitatif. Teknik pengumpulan data yaitu dengan melakukan wawancara dan studi pustaka berupa realisasi BPHTB setiap tahun dan peraturan daerah tentang BPHTB yang berlaku. Di kota Tomohon, pemungutan pajak BPHTB berdasarkan Peraturan Daerah No. 2 tahun 2011 dan dilaksanakan oleh BPKPD Kota Tomohon dengan menggunakan sistem self assesment. Adapun dalam pelaksanaan pemungutan BPHTB ini tak lepas dari peran notaris/PPAT dan pihak kecamatan dalam hal ini camat sebagai PPATS. Tarif BPHTB yang dikenakan sebesar 5%. Berdasarkan hasil penelitian menunjukan bahwa pemungutan BPHTB di kota Tomohon telah berjalan dengan baik, dapat dilihat dari realisasi BPHTB selama beberapa tahun terakhir yang melebihi target, namun adapun tahun tertentu yang sangat jauh dibawah target. Hal ini karena sifat BPHTB yang tidak memiliki potensi penerimaan pajak yang jelas dan menentu.

Abstract
This study aims to determine how the implementation of BPHTB collection in Tomohon City. This research uses descriptive exploratory method with a qualitative approach. Data collection techniques are by conducting interviews and literature study in the form of the realization of the BPHTB every year and the regional regulations on BPHTB that are in effect. In the city of Tomohon, BPHTB tax collection is based on Regional Regulation No. 2 of 2011 and implemented by BPKPD Tomohon City using a self-assessment system. As for the implementation of this BPHTB collection, it cannot be separated from the role of the notary / PPAT and the sub-district party, in this case the sub-district head as PPATS. The BPHTB rate is 5%. Based on the results of the study, it shows that the collection of BPHTB in Tomohon City has been going well, it can be seen from the realization of BPHTB over the last few years that has exceeded the target, but there are certain years that are far below the target. This is due to the nature of BPHTB which does not have clear and definite tax revenue potential.
Pengaruh Anggaran Berbasis Kinerja Terhadap Kinerja Aparatur Pemerintah Daerah di Kabupaten Minahasa
Authors: Wongkar Don Leonardo , Senduk Ventje , Tanor Linda 
Published: September 2021

Fenomena penyerapan anggaran yang kurang maksimal terjadi pada setiap Satuan Kerja Perangkat Daerah Pemerintah Kabupaten Minahasa, dimana permasalahan yang terjadi yaitu penyerapan anggaran yang kurang maksimal, tidak melaporkan laporan realisasi penyerapan keuangan maupun fisik sesuai jadwal yang di tetapkan, kurang matangnya perencanaan, adanya berbagai kendala. Penelitian ini menggunakan metode kuantitatif, yang bertujuan untuk melihat pengaruh anggaran berbasis kinerja terhadap kinerja aparatur pemerintah daerah di kabupaten minahasa. Populasi dalam penelitian ini adalah 264 orang ASN Dinas/Badan dengan sampel 53 orang ASN (20%) dari populasi. Teknik pengambilan data dalam penelitian ini menggunakan metode angket/kuesioner. Hasil uji hipotesis memperlihatkan bahwa anggaran berbasis kinerja mempunyai tingkat signifikansi sebesar 0,040 yaitu lebih kecil dari 0,05 yang artinya H1 diterima dan bisa disimpulkan bahwa Variable anggaran berbasis kinerja memberikan pengaruh positif kepada variable kinerja aparatur pemerintah daerah dengan presentase 13,7%.
Mapeamento de competências do bibliotecário para uma atuação na indústria
Authors: Araújo Vanessa Silva , Inomata Danielly Oliveira 
Published: September 2021

Introdução:apresenta a investigação sobre as competências necessárias para a atuação do bibliotecário na indústria, as quais foram identificadas na literatura, servindo como base para a pesquisa de campo realizada em uma indústria do Pólo Industrial de Manaus, e posteriormente validadas por especialistas no assunto. Método: a pesquisa caracteriza-se por ser exploratória, descritiva, de natureza qualitativa, na qual a pesquisa bibliográfica fundamentou a pesquisa de campo, cujos dados foram coletados por meio de formulário eletrônico. Resultados: foram identificadas as competências necessárias para a atuação do bibliotecário na indústria, verificando-se que as competências propostas a partir da literatura estão de acordo com a atuação do bibliotecário no campo de atuação. Conclusão: concluiu-se que há a necessidade de bibliotecários na indústria para lidar com a informação neste ambiente, sendo que as competências identificadas orientam esta atuação, garantindo melhor desempenho nas atividades da indústria.
Integrated Community Collaborative Care for Seniors with Depression/Anxiety and any Physical Illness
Authors: Shulman Richard , Arora Reenu , Geist Rose , Ali Amna , Ma Julia , Mansfield Elizabeth , Martel Sara , Sandercock Jane , Versloot Judith 
Published: September 2021

Background
We report on the feasibility and effectiveness of an integrated community collaborative care model in improving the health of seniors with depression/anxiety symptoms and chronic physical illness.
Methods
This community collaborative care model integrates geriatric medicine and geriatric psychiatry with care managers (CM) providing holistic initial and follow-up assessments, who use standardized rating scales to monitor treatment and provide psychotherapy (ENGAGE). The CM presents cases in a structured case review to a geriatrician and geriatric psychia­trist. Recommendations are communicated by the CM to the patient’s primary care provider.
Results
187 patients were evaluated. The average age was 80 years old. Two-thirds were experiencing moderate-to-severe depres­sion upon entry and this proportion decreased significantly to one-third at completion. Qualitative interviews with patients, family caregivers, team members, and referring physicians indicated that the program was well-received. Patients had on average six visits with the CM without the need to have a face-to-face meeting with a specialist.
Conclusion
The evaluation shows that the program is feasible and effect­ive as it was well received by patients and patient outcomes improved. Implementation in fee-for-service publicly funded health-care environments may be limited by the need for dedicated funding.
Factors Associated With Patient Engagement in Shared Decision-Making for Stroke Prevention Among Older Adults with Atrial Fibrillation
Authors: Mehawej Jordy , Saczysnki Jane , Abu Hawa O. , Gagnier Marc , Bamgbade Benita , Lessard Darleen , Trymbulak Katherine , Saliba Connor , Kiefe Catarina , Goldberg Robert , McManus David 
Published: September 2021

Objective
To examine the extent of, and factors associated with, patient engagement in shared decision-making (SDM) for stroke prevention among patients with atrial fibrillation (AF).
Methods
We used data from the Systematic Assessment of Geriatric Elements-Atrial Fibrillation study which includes older ( ≥65 years) patients with AF and a CHA2DS2-VASc≥2. Partici­pants reported engagement in SDM by answering whether they actively participated in choosing to take an oral antico­agulant (OAC) for their condition. Multiple logistic regression was used to assess associations between sociodemographic, clinical, geriatric, and psychosocial factors and patient en­gagement in SDM.
Results
A total of 807 participants (mean age 75 years; 48% female) on an OAC were studied. Of these, 61% engaged in SDM. Older participants (≥80 years) and those cognitively impaired were less likely to engage in SDM, while those very know­ledgeable of their AF associated stroke risk were more likely to do so than respective comparison groups.
Conclusions
A considerable proportion of older adults with AF did not engage in SDM for stroke prevention with older patients and those cognitively impaired less likely to do so. Clinicians should identify patients who are less likely to engage in SDM, promote patient engagement, and foster better patient-provider communication which may enhance long- term patient outcomes.
COVID-19 and Long-Term Care: the Essential Role of Family Caregivers
Authors: Hindmarch Whitney , McGhan Gwen , Flemons Kristin , McCaughey Deirdre 
Published: September 2021

Background
Those most at risk from severe COVID-19 infection are older adults; therefore, long-term care (LTC) facilities closed their doors to visitors and family caregivers (FCGs) during the initial wave of the COVID-19 pandemic. The most common chronic health condition among LTC residents is dementia, and persons living with dementia (PLWD) rely on FCGs to maintain their care provision. This study aims to evaluate the impact of visitor restrictions and resulting loss of FCGs providing in-person care to PLWD in LTC during the first wave of the COVID-19 pandemic.
Method
An online survey and follow-up focus groups were conducted June to September 2020 (n=70). Mixed quantitative (descrip­tive statistics) and qualitative (thematic analysis) methods were used to evaluate study data.
Results
FCGs were unable to provide in-person care and while al­ternative communication methods were offered, they were not always effective. FCGs experienced negative outcomes including social isolation (66%), strain (63%), and reduced quality of life (57%). PLWD showed an increase in responsive behaviours (51%) and dementia progression. Consequently, 85% of FCGs indicated they are willing to undergo specialized training to maintain access to their PLWD.
Conclusion
FCGs need continuous access to PLWD they care for in LTC.
Follow-up Evaluation of Medial Clear Space and Talar Tilt After Bimalleolar Equivalent Fracture Fixation Without Primary Deltoid Repair
Authors: Ryba Dalton , Ernst Jordan , Blair Somer , Motley Travis A. 
Published: September 2021

Background
We sought first to determine the efficacy of lateral ankle fixation alone in maintenance of medial clear space and talar valgus in bimalleolar equivalent ankle fractures not receiving primary deltoid repair, and second to assess perceived outcomes via the Foot and Ankle Outcome Score. To our knowledge, no study has quantified the reduction of medial clear space and talar valgus in bimalleolar equivalent ankle fractures receiving lateral ankle fixation alone.

Methods
We compared preoperative, initial postoperative, and greater than 1-year follow-up radiographs of medial clear space and talar valgus in individuals who received lateral ankle fixation alone in bimalleolar equivalent ankle fractures. Subjective outcomes were measured via the Foot and Ankle Outcome Score.

Results
Thirty-seven patients participated in the study and showed a statistically significant reduction of medial clear space and restoration of talar position, and maintenance with this fixation method during follow-up in patients with bimalleolar equivalent ankle fractures. Adjunctively, patients perceived their outcomes to be satisfactory, as demonstrated by the results of the Foot and Ankle Outcome Score.

Conclusions
We aimed to assess the efficacy of lateral ankle fixation in the maintenance of medial clear space and talar valgus reduction at midterm follow-up. Although some authors contend that primary deltoid repair in bimalleolar equivalent ankle fractures is warranted, these midterm study results suggest that isolated lateral ankle fixation is adequate for medial ankle stabilization in bimalleolar equivalent fractures, and thus primary deltoid repair is not indicated.
Antioxidant Activities of the Aqueous Extracts of Pedalium murex D. Royen EX L. Fruit and Leafy Stem
Authors: Dossou-Agoin Gerard Bessan , Ganfon Habib , Assogba Fidèle , Gbankoto Adam , Gbenou Joachim , Anatole Laleye 
Published: September 2021

Aims: The leafy stem and fruit of P.murex have been reported to be used in folk medicine to treat male reproductive system ailments. This study was undertaken to assess the antioxidant potential of the aqueous extracts of P.murex leafy stem and fruit.
Methodology: Extracts were prepared by macerating the powder in water. Total phenolics amount were determined by Folin-Ciocalteu reagent, flavonoids were quantified by aluminum chloride method and total tannin content was estimated by hexacyanoferric method. The in vitro antioxidant activity of the extracts were assessed through 2,2´-diphenyl-1-picrylhydrazyl (DPPH) scavenging assay, reducing power assay, hydrogen peroxide (H2O2) inhibition assay and lipid peroxidation assay.
Results: Total phenolic compounds, flavonoids and tannins content were respectively equal to 48.91± 1.67 µg/mg Gallic Acid Equivalents (GAE); 56.01± 0.90 µg/mg Rutin Equivalents (RUE); 16.92± 1.22 µg/mg Tannic Acid Equivalents (TAE) for the leafy stem extract while they were equal to 26.26± 0.54 µg/mg GAE; 47.88± 2.39 µg/mg RUE; 7.94± 0.31 µg/mg TAE for the fruit. The leafy stem extract exhibited a more pronounced DPPH scavenging activity, reducing power, hydrogen peroxide scavenging activity and lipid peroxidation activity than the fruit extract.
Conclusion: The antioxidant activity of the leafy stem aqueous extract was significantly more potent than that of the fruit extract. Further studies will find out the extracts pharmacological efficacy and innocuity.