bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multi-center nationwide study on pediatric psychiatric inpatients 2000–2018: length of stay, recurrent hospitalization, functioning level, suicidality, violence and diagnostic profiles
Authors: Kronström Kim , Tiiri Elina , Vuori Miika , Ellilä Heikki , Kaljonen Anne , Sourander Andre 
Published: November 2021

AbstractInpatient treatment is an important part of child and adolescent psychiatric (CAP) care. This nationwide study explores the changes in length of stay, recurrent hospitalization, functioning level, suicidality, violence and diagnoses of CAP inpatients in Finland in 2000, 2011 and 2018. We obtained comprehensive questionnaire data on each study year from 93 to 95% of all CAP wards in Finland. We split the 1276 inpatients into two age groups in each study year: under 13 and 13–18. The median length of stay in inpatient treatment decreased from 82.0 days in 2000 to 20.5 days in 2018 (p < 0.001) and recurrent hospitalization increased from 38 to 46%. General functioning, which was evaluated by the Children’s Global Assessment Scale, deteriorated by an average of six points between 2000 and 2018. Violent threats decreased from 21.5 to 16.6% and violent acts decreased from 26.9 to 20.3%. Suicidal threats decreased from 42.6 to 23.3% in those aged under 13 and remained stable among those aged 13–18. In the 13–18 group, there was an increase in the diagnoses of ADHD, from 5.0 to 16.9% and depression, from 25.1 to 41.7%. However, psychosis decreased from 23.2 to 12.6% in the older age group. In the whole cohort, anxiety disorders increased from 7.6 to 15.6%. The overall picture does not show that CAP inpatients have become more disturbed. While the general functioning of CAP inpatients deteriorated somewhat over the 2000–2018 study period, symptoms of suicidality and violence remained stable or decreased. There was also a continuous increase in short-term treatment.
Performance of the eazyplex® BloodScreen GN as a simple and rapid molecular test for identification of Gram-negative bacteria from positive blood cultures
Authors: Bach Katharina , Edel Birgit , Höring Steffen , Bartoničkova Lucie , Glöckner Stefan , Löffler Bettina , Bahrs Christina , Rödel Jürgen 
Published: November 2021

AbstractThe LAMP-based eazyplex® BloodScreen GN was evaluated for the detection of frequent Gram-negatives directly from positive blood culture (BC) bottles. A total of 449 BCs were analyzed. Sensitivities and specificities were 100% and 100% for Escherichia coli, 95.7% and 100% for Klebsiella pneumoniae, 100% and 100% for blaCTX-M, 100% and 100% for Klebsiella oxytoca, 100% and 99% for Proteus mirabilis, and 100% and 99.8% for Pseudomonas aeruginosa, respectively. The time to result ranged from 8 to 16 min, plus about 6 min for sample preparation. The eazyplex® BloodScreen GN is a reliable molecular assay for rapid BC testing.
Short- and medium-term cost effects of non-indicated thyroid diagnostics: empirical evidence from German claims data
Authors: Hafner Lucas , Biermann Valeria , Hueber Susann , Donnachie Ewan , Kühlein Thomas , Tauchmann Harald , Tomandl Johanna 
Published: November 2021

AbstractThis paper contributes to the discussion of whether non-indicated ultrasound examinations of the thyroid gland contribute to overtreatment and excess health care expenditures. Using two sources of claims data from Germany, we analyzed data from patients who underwent a TSH blood test which is the initial diagnostic measure to check for possible presence of thyroid dysfunction. In a matching analysis, we compared health costs of two groups of patients. One consisted of patients who underwent an early thyroid ultrasound that according to medical guidelines—at this point—was probably not indicated. The other group consisted of patients, who underwent no ultrasound examination at all or later in the course of the disease, making probable a correct indication. Both groups were made comparable by the means of a matching procedure. Average thyroid-specific health costs were substantially higher for the first group in the quarter in which the ultrasound examination took place. Some deviation in these specific costs persisted over a substantial period of time, with drug expenditures exhibiting the biggest difference. If, however, total health costs were considered, difference in costs was only found in the initial quarter. We conclude that non-indicated ultrasound examination of the thyroid gland may have some moderate effects on thyroid-specific costs. Yet the data do not suggest that long-lasting overtreatment and excess health expenditures are initiated by non-indicated ultrasound in Germany.
A behavioural study of obedience in health professional students
Authors: Violato Efrem , Witschen Brian , Violato Emilio , King Sharla 
Published: November 2021

AbstractInterprofessional Education and Collaborative Practice (IPECP) is a field of study suggested to improve team functioning and patient safety. However, even interprofessional teams are susceptible to group pressures which may inhibit speaking up (positive deviance). Obedience is one group pressure that can inhibit positive deviance leading to negative patient outcomes. To examine the influence of obedience to authority in an interprofessional setting, an experimental simulated clinical scenario was conducted with Respiratory Therapy (RT) (n = 40) and Advanced Care Paramedic (ACP) (n = 20) students. In an airway management scenario, it was necessary for students to challenge an authority, a senior anesthesiologist, to prevent patient harm. In a 2 × 2 design cognitive load and an interventional writing task designed to increase positive deviance were tested. The effect of individual characteristics, including Moral Foundations, and displacement of responsibility were also examined. There was a significant effect for profession and cognitive load: RT students demonstrated lower levels of positive deviance in the low cognitive load scenario than students in other conditions. The writing task did not have a significant effect on RT or ACP students’ behaviour. The influence of Moral Foundations differed from expectations, In Group Loyalty was selected as a negative predictor of positive deviance while Respect for Authority was not. Displacement of responsibility was influential for some participants thought not for all. Other individual variables were identified for further investigation. Observational analysis of the simulation videos was conducted to obtain further insight into student behaviour in a compliance scenario. Individual differences, including experience, should be considered when providing education and training for positive deviance. Simulation provides an ideal setting to use compliance scenarios to train for positive deviance and for experimentation to study interprofessional team behaviour.
A configurable fluorescence sensing front-end for ultra-low power and high sensitivity applications
Authors: Rafati Maryam , Qasemi Seyed Ruhallah , Alvandpour Atila 
Published: November 2021

AbstractThis paper presents an ultra-low power, high sensitivity configurable CMOS fluorescence sensing front-end for implantable biosensors at single-cell level measurements. The front-end is configurable by a set of switches and consists of three integrated photodiodes (PD), three transimpedance amplifiers (TIA) for detecting a current range between 1 pA up to 10 mA. Also, an ambient light canceling technique is proposed to make the sensor operate under different environmental conditions. The proposed front-end could be configured for ultra-low light detection or ultra-low power consumption. The circuit is designed and fabricated in a 0.35 µm standard CMOS technology, and the measurement results are presented. The minimum integrated input-referred current noise is measured as 1.07 pA with the total average power consumption of 61.8 µW at an excitation frequency of 80 Hz. For ultra-low-power configuration, the front-end has an average power consumption of 119 nW and input integrated current noise of 210 pA at an excitation frequency of 20 kHz.
“A little bit more looking…listening and feeling” A qualitative interview study exploring advanced clinical practice in primary care and community pharmacy
Authors: Seston Elizabeth Mary , Schafheutle Ellen Ingrid , Willis Sarah Caroline 
Published: November 2021

AbstractBackground Growing demands on healthcare globally, combined with workforce shortages, have led to greater skill mix in healthcare settings. Pharmacists are increasingly moving into complex areas of practice, a move supported by policy and education/training changes. Aim To understand the nature of extended roles for pharmacists practising at an advanced level in primary care and community pharmacy settings, to explore how clinical and physical examination was incorporated into practice and to understand the impact of providing such examination on practice and on patient relationships. Method Telephone interviews (N = 15) were conducted with a purposive sample of pharmacists using clinical and physical examination in their practice in Great Britain. The sample included primary care pharmacists (N = 5), community pharmacists (N = 4), pharmacists working across settings (N = 5) and one working in another primary care setting. Participants were recruited through professional networks, social media and snowballing. Results Primary care pharmacists and community pharmacists were utilising clinical and physical examination skills in their practice. Some community pharmacists were operating locally-commissioned services for low acuity conditions. Incorporating such examinations into practice enabled pharmacists to look at the patient holistically and enhanced pharmacist/patient relationships. Barriers to practise included lack of timely sharing of patient data and perceived reluctance on the part of some pharmacists for advanced practice. Conclusion With growing opportunities to provide patient-focussed care, it remains to be seen whether pharmacists, both in Great Britain and elsewhere, are able to overcome some of the organisational, structural and cultural barriers to advanced practice that currently exist in community pharmacy.
Superdifferential Analysis of the Takagi-Van Der Waerden Functions
Authors: Ferrera Juan , Gil Javier Gómez , Llorente Jesús 
Published: November 2021

AbstractIn this work we completely describe the superdifferential of the Takagi-Van der Waerden functions and, as a consequence, the local maxima of these functions are characterized. Regarding the set of points where the superdifferential is not empty, we calculate its Hausdorff dimension as well as its corresponding Hausdorff measure. To do so, for any even integer greater than or equal to two we determine the 1/2-dimensional Hausdorff measure of the set of points where Takagi-Van der Waerden functions attain their global maximum.
Virtual embolization for treatment support of intracranial AVMs using an interactive desktop and VR application
Authors: Sprengel Ulrike , Saalfeld Patrick , Stahl Janneck , Mittenentzwei Sarah , Drittel Moritz , Behrendt Benjamin , Kaneko Naoki , Behme Daniel , Berg Philipp , Preim Bernhard , Saalfeld Sylvia 
Published: November 2021

Abstract
Purpose
The treatment of intracranial arteriovenous malformations (AVM) is challenging due to their complex anatomy. For this vessel pathology, arteries are directly linked to veins without a capillary bed in between. For endovascular treatment, embolization is carried out, where the arteries that supply the AVM are consecutively blocked. A virtual embolization could support the medical expert in treatment planning.

Method
We designed and implemented an immersive VR application that allows the visualization of the simulated blood flow by displaying millions of particles. Furthermore, the user can interactively block or unblock arteries that supply the AVM and analyze the altered blood flow based on pre-computed simulations.

Results
In a pilot study, the application was successfully adapted to three patient-specific cases. We performed a qualitative evaluation with two experienced neuroradiologist who regularly conduct AVM embolizations. The feature of virtually blocking or unblocking feeders was rated highly beneficial, and a desire for the inclusion of quantitative information was formulated.

Conclusion
The presented application allows for virtual embolization and interactive blood flow visualization in an immersive virtual reality environment. It could serve as useful addition for treatment planning and education in clinical practice, supporting the understanding of AVM topology as well as understanding the influence of the AVM’s feeding arteries.
Tractable circula densities from Fourier series
Authors: Kato Shogo , Pewsey Arthur , Jones M. C. 
Published: November 2021

AbstractThis article proposes an approach, based on infinite Fourier series, to constructing tractable densities for the bivariate circular analogues of copulas recently coined ‘circulas’. As examples of the general approach, we consider circula densities generated by various patterns of nonzero Fourier coefficients. The shape and sparsity of such arrangements are found to play a key role in determining the properties of the resultant models. The special cases of the circula densities we consider all have simple closed-form expressions involving no computationally demanding normalizing constants and display wide-ranging distributional shapes. A highly successful model identification tool and methods for parameter estimation and goodness-of-fit testing are provided for the circula densities themselves and the bivariate circular densities obtained from them using a marginal specification construction. The modelling capabilities of such bivariate circular densities are compared with those of five existing models in a numerical experiment, and their application illustrated in an analysis of wind directions.
Classification and evaluation of tight sandstone reservoirs based on diagenetic facies: a case study on Chang 6 reservoir in the center-west Ordos Basin
Authors: Zhanwu Gao , Jian Shi , Qichao Xie , Yan Zhou , Shuxun Zhou 
Published: November 2021

AbstractTight sandstone reservoirs dominated by are developed in the Chang 6 oil layer group of the Yanchang Formation in the central-western part of the Ordos Basin. Featuring the lacustrine delta facies, Chang 6 formation in the center-west area of Ordos Basin shows an increasing petroleum reserve expectation. Its exploitation practice, however, has many problems caused by tight sandstone reservoir features. According to diagenetic and pore analysis, the diagenetic facies in the study area are grouped into four types: chlorite-film-intergranular-pore, feldspar-dissolution, clay-cemented-micropore, carbonate-cemented-tightness for their obvious differences in mineral feature and pore evolution. By introducing the comprehensive classification parameter synthesized from 9 other parameters, the reservoir quality is divided up into four levels: I(Feci > 1), II(3 ≤ Feci ≤ 7), III(-2 ≤ Feci ≤ 3), IV(Feci ≤ -2). The reservoir quality division matches well with the diagenetic facies group. To decide the diagenetic type and reservoir quality division in all wells, the logging data are utilized with the Fisher discriminant method, which has obtained a good performance. The method enables the reservoir quality analysis expanding to all wells from samples, which is helpful for exploitation of the study area.
Numerical analysis of wave–structure interaction of regular waves with surface-piercing inclined plates
Authors: Cummins C. P. , Scarlett G. T. , Windt C. 
Published: November 2021

AbstractThe Mocean wave energy converter consists of two sections, hinged at a central location, allowing the device to convert energy from the relative pitching motion of the sections. In a simplified form, the scattering problem for the device can be modelled as monochromatic waves incident upon a thin, inclined, surface-piercing plate of length $$L'$$

L
′

in a finite depth $$d'$$

d
′

of water. In this paper, the flow past such a plate is solved using a Boundary Element Method (BEM) and Computational Fluid Dynamics (CFD). While the BEM solution is based on linear potential flow theory, CFD directly solves the Navier–Stokes equations. Problems of this type are known to exhibit near-perfect reflection (indicated by a reflection coefficient $$|R|\approx 1$$

|
R
|
≈
1

) of waves at specific wavenumbers $$k'$$

k
′

. In this paper, we show that the resonant motion of the fluid induces large hydrodynamic forces on the plate. Furthermore, we argue that this low-frequency resonance resembles Helmholtz resonance, and that Mocean’s device being able to tune to these low frequencies does not act like an attenuator. For the case where the water is deep ($$d'>\lambda '/2$$

d
′

>

λ
′

/
2

, where $$\lambda '=2\pi /k'$$

λ
′

=
2
π
/

k
′

), we find excellent agreement between our simulations and previous semi-analytical studies on the value of the resonant wave periods in deep water. We also find excellent agreement between the excitation forces on the plate computed using the BEM model, analytical results, and CFD for large inclination angles ($$\alpha > 45^\circ $$

α
>

45
∘

). For $$\alpha \le 15^\circ $$

α
≤

15
∘

, both methods show the same trend, but the CFD predicts a significantly smaller peak in the excitation force compared with BEM, which we attribute to non-linear effects such as the non-linear Froude–Krylov force
OCR with Tesseract, Amazon Textract, and Google Document AI: a benchmarking experiment
Authors: Hegghammer Thomas 
Published: November 2021

AbstractOptical Character Recognition (OCR) can open up understudied historical documents to computational analysis, but the accuracy of OCR software varies. This article reports a benchmarking experiment comparing the performance of Tesseract, Amazon Textract, and Google Document AI on images of English and Arabic text. English-language book scans (n = 322) and Arabic-language article scans (n = 100) were replicated 43 times with different types of artificial noise for a corpus of 18,568 documents, generating 51,304 process requests. Document AI delivered the best results, and the server-based processors (Textract and Document AI) performed substantially better than Tesseract, especially on noisy documents. Accuracy for English was considerably higher than for Arabic. Specifying the relative performance of three leading OCR products and the differential effects of commonly found noise types can help scholars identify better OCR solutions for their research needs. The test materials have been preserved in the openly available “Noisy OCR Dataset” (NOD) for reuse in future benchmarking studies.
Nursing Students’ Competency to Attend Disaster Situations: A Study in Western Iran
Authors: Kaviani Fatemeh , Aliakbari Fatemeh , Sheikhbardsiri Hojjat , Arbon Paul 
Published: November 2021

AbstractObjective:The disaster preparedness of nurses is important as nurses are members of a health care team that needs to work systematically and collaboratively in all conditions. Although education and training naturally underpin effective practice, disaster nursing education is rarely provided to nurses in Iran. Because disaster situations, by definition, overwhelm health services, it is likely that nursing students will be required to join their colleagues in the response. The purpose of this study was to evaluate the competency of nursing students to attend disaster situations.Methods:This descriptive, analytical study was conducted in western Iran in 2020. A total of 70 nursing students in the fourth (final) year of their undergraduate nursing education entered the study by a census sampling method. Data collection was undertaken using a validated disaster competency assessment questionnaire. The data were analyzed using SPSS version 21 (IBM Corp, Armonk, NY) with descriptive and analytic tests.Results:The mean age of participants was 21.4 ± 2.14 and 57.1% of them were women; 45 participants (64.3%) had received no disaster-related training, and 88.6% had no history of participating in disaster exercises. The total score for nursing students’ competence was 125.58 ± 14.19. There was a significant relationship between the mean score of nursing competence in response to disasters and student history of participating in an exercise and training course (P< 0.001).Conclusion:Students’ competence in disaster situations is poor. Awareness of the competence condition of nurses is the first step to improve their preparedness as the most key members of the disaster health team. Conducting disaster-related training may be appropriate. The results of this study can provide evidence for the development of educational policies in disaster nursing education.
Statistical Evidence and the Problem of Specification
Authors: Schauer Frederick 
Published: November 2021

AbstractPhilosophical debates over statistical evidence have long been framed and dominated by L. Jonathan Cohen's Paradox of the Gatecrasher and a related hypothetical example commonly called Prison Yard. These examples, however, raise an issue not discussed in the large and growing literature on statistical evidence – the question of what statistical evidence is supposed to be evidence of. In actual practice, the legal system does not start with a defendant and then attempt to determine if that defendant has committed some unspecified or under-specified act, as these examples appear to suppose. Rather, both criminal and civil litigation start with a sufficiently specified act and then attempt to determine if the defendant has committed it. And when we start with a more fully specified act, the statistics look very different, and these prominent examples no longer present the paradox they are claimed to support. Examining the issue of specification, however, does more than simply undercut the prominent examples in a long and extensive literature. The examination also raises normative issues challenging the legal system's traditional reluctance to base liability on the conjunction of probabilities.