bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cybersickness in current-generation virtual reality head-mounted displays: systematic review and outlook
Authors: Caserman Polona , Garcia-Agundez Augusto , Gámez Zerban Alvar , Göbel Stefan 
Published: April 2021

AbstractCybersickness (CS) is a term used to refer to symptoms, such as nausea, headache, and dizziness that users experience during or after virtual reality immersion. Initially discovered in flight simulators, commercial virtual reality (VR) head-mounted displays (HMD) of the current generation also seem to cause CS, albeit in a different manner and severity. The goal of this work is to summarize recent literature on CS with modern HMDs, to determine the specificities and profile of immersive VR-caused CS, and to provide an outlook for future research areas. A systematic review was performed on the databases IEEE Xplore, PubMed, ACM, and Scopus from 2013 to 2019 and 49 publications were selected. A summarized text states how different VR HMDs impact CS, how the nature of movement in VR HMDs contributes to CS, and how we can use biosensors to detect CS. The results of the meta-analysis show that although current-generation VR HMDs cause significantly less CS ($$p<0.001$$

p
<
0.001

), some symptoms remain as intense. Further results show that the nature of movement and, in particular, sensory mismatch as well as perceived motion have been the leading cause of CS. We suggest an outlook on future research, including the use of galvanic skin response to evaluate CS in combination with the golden standard (Simulator Sickness Questionnaire, SSQ) as well as an update on the subjective evaluation scores of the SSQ.
Exact parametric causal mediation analysis for a binary outcome with a binary mediator
Authors: Doretti Marco , Raggi Martina , Stanghellini Elena 
Published: April 2021

AbstractWith reference to causal mediation analysis, a parametric expression for natural direct and indirect effects is derived for the setting of a binary outcome with a binary mediator, both modelled via a logistic regression. The proposed effect decomposition operates on the odds ratio scale and does not require the outcome to be rare. It generalizes the existing ones, allowing for interactions between both the exposure and the mediator and the confounding covariates. The derived parametric formulae are flexible, in that they readily adapt to the two different natural effect decompositions defined in the mediation literature. In parallel with results derived under the rare outcome assumption, they also outline the relationship between the causal effects and the correspondent pathway-specific logistic regression parameters, isolating the controlled direct effect in the natural direct effect expressions. Formulae for standard errors, obtained via the delta method, are also given. An empirical application to data coming from a microfinance experiment performed in Bosnia and Herzegovina is illustrated.
Six-year clinical outcomes of implant-supported acrylic vs. ceramic superstructures according to the All-on-4 treatment concept for the rehabilitation of the edentulous maxilla
Authors: Ayna Mustafa , Karayürek Fatih , Jepsen Søren , Emmert Marie , Acil Yahya , Wiltfang Jörg , Gülses Aydin 
Published: April 2021

AbstractThe aim of the current study was to document the long-term clinical results of the use of two prosthetic techniques for the rehabilitation of completely edentulous maxillae according to the “All-on-Four” concept: Fixed, screw-retained prosthesis mounted on a chrome-molybdenum framework with (1) metal-ceramic veneers and (2) Acrylic prosthesis with acrylic resin prosthetic teeth. A total of 34 patients were assigned to subgroups according to their own preference of the superstructure type (ceramics [n: 17] or acrylic resin [n: 17]). Prosthetic complications, marginal bone loss, plaque accumulation, bleeding on probing, bite force and oral-health-related quality of life were assessed over a period of 6 years. Marginal bone loss around implants of the ceramic group remained well within the limits for ‘success’, as defined by the 2007 Pisa consensus over the time (1.43 ± 0.35 mm). However, marginal bone loss was significantly more pronounced around the implants in the acrylic group (2.15 ± 0.30) and the difference between two groups was statistically significant (p: 0.00). Bleeding on probing and plaque accumulation showed also positive correlation with marginal bone loss. Both acrylic and ceramic suprastructures appeared to be equivalent after 6 years; however, ceramic suprastructures revealed superior clinical results in terms of bone loss and plaque accumulation. Current study determines the long-term clinical outcomes of different prosthetic management alternatives in All-on-Four and aids to increase dental professionals’ ability to meet the patients’ expectations.
Monitoring land use and soil salinity changes in coastal landscape: a case study from Senegal
Authors: Thiam Sophie , Villamor Grace B. , Faye Laurice C. , Sène Jean Henri Bienvenue , Diwediga Badabate , Kyei-Baffour Nicholas 
Published: April 2021

AbstractSoil salinity is a major issue causing land degradation in coastal areas. In this study, we assessed the land use and soil salinity changes in Djilor district (Senegal) using remote sensing and field data. We performed land use land cover changes for the years 1984, 1994, 2007, and 2017. Electrical conductivity was measured from 300 soil samples collected at the study area; this, together with elevation, distance to river, Normalized Difference Vegetation Index (NDVI), Salinity Index (SI), and Soil-Adjusted Vegetation Index (SAVI), was used to build the salinity model using a multiple regression analysis. Supervised classification and intensity analysis were applied to determine the annual change area and the variation of gains and losses. The results showed that croplands recorded the highest gain (17%) throughout the period 1984–2017, while forest recorded 3%. The fastest annual area of change occurred during the period 1984–1994. The salinity model showed a high potential for mapping saline areas (R2 = 0.73 and RMSE = 0.68). Regarding salinity change, the slightly saline areas (2 < EC < 4 dS/m) increased by 42% whereas highly saline (EC > 8 dS/m) and moderately saline (4 < EC < 8 dS/m) areas decreased by 23% and 26%, respectively, in 2017. Additionally, the increasing salt content is less dominant in vegetated areas compared with non-vegetated areas. Nonetheless, the highly concentrated salty areas can be restored using salt-resistant plants (e.g., Eucalyptus sp., Tamarix sp.). This study gives more insights on land use planning and salinity management for improving farmers’ resilience in coastal regions.
Accepting the Exceptional?
Authors: Zwier Jochem 
Published: April 2021

AbstractThis commentary attempts to contribute to a further elucidation of Dominic Smith’s call for a rehabilitation of the transcendental in philosophy of technology. On the one hand, it focuses on why such a rehabilitation is deemed necessary, particularly in light of Smith’s diagnosis of a contemporary tendency towards reification and presentism. Postphenomenology is discussed as a challenge and invitation to further clarify the stakes. On the other hand, this commentary inquires into how Smith envisages the achievement of a rehabilitation of the transcendental. Further attention is given to Smith’s idea of a renewed sense of the transcendental. Following his own cues and situating this renewal in the philosophical tradition, the question whether the involved philosophical praxis should be primarily understood as political is brought to the fore. In so doing, Smith’s reading and extension of Luciano Floridi’s attempts to move beyond Kant receive special attention, since the transcendental is here understood in terms of conditions of feasibility. The challenge put to Smith is to contrast this approach with social-constructivist approaches on the one hand, and Stiegler’s thought regarding technics and the transcendental on the other. Finally, Smith’s commitment to taking exception is analyzed to ask how and which logic is at play there.
Towards a signature pedagogy for design and technology education: a literature review
Authors: McLain Matt 
Published: April 2021

AbstractDrawing on the work of Lee Shulman, this article reviews literature exploring the concept of signature pedagogies, which are described as having have surface, deep and implicit structures. These structures are complex and changing; concerned with habits of head, hand and heart. Emerging from professional education and now being explored in STEM and Humanities education, they are characteristic forms of teaching and learning that are common across a sector. Common themes emerge from within a range of disciplines including art, built environment, design, music, religious, social work and teacher education. These include the roles of the curriculum, the teacher, the learning environment, as well as capability, uncertainty and the challenges associated with signature pedagogies. Focusing on literature from design education, the paper explores the nature of signature pedagogy in design and technology, as a tool for professional discourse. The conclusions propose a discursive framework for design and technology education in which the structures are tied together by the three fundamental activities of ideating, realising and critiquing; more commonly thought of as designing, making and evaluating. The deep structure being project-based learning, undergirded by the implicit values and attitudes associated with design thinking; including collaboration, creativity, empathy, iteration and problem solving. Design and technology education has something unique to offer the broad and balanced curriculum through its signature pedagogies and the way that knowledge is experienced by learners.
Clinical evaluation of a novel subcutaneous lactate monitor
Authors: Dror Nitsan , Weidling John , White Sean , Ortenzio Francesca , Shreim Samir , Keating Mark T. , Pham Hoang , Radom-Aizik Shlomit , Botvinick Elliot 
Published: April 2021

AbstractLactate levels are commonly used as an indirect measure to assess metabolic stress in clinical conditions like sepsis. Dynamic lactate measurements are recommended to assess and guide treatment in patients with shock and other critical care conditions. A minimally invasive, continuous lactate monitor has potential to improve clinical decisions and patient care. The purpose of the study was to evaluate continuous lactate measurements of a novel enzymatic Continuous Lactate Monitor (CLM) developed in our laboratory. Lactate levels were monitored during incremental cycling exercise challenges as a tool for hyperlactatemia. Six healthy individuals 18–45 y/o (4 males, 2 females) participated in the study. CLM devices were inserted subcutaneously in the postero-lateral trunk below the renal angle, one hour before the exercise challenge. Each exercise challenge consisted of a 3 to 12-min warm up period, followed by up to 7, 4-min incremental workload bouts separated by rest intervals. Continuous lactate measurements obtained from CLM were compared with commercial lactate analyzer (Abbott iSTAT) measurements of venous blood (plasma) drawn from the antecubital vein. Blood was drawn at up to 25 time points spanning the duration of before exercise, during exercise, and up to 120 min post exercise. Area under the curve (AUC), and delay time were calculated to compare the CLM readings with plasma lactate concentration. Average plasma lactate concentration increased from 1.02 to 16.21 mM. Ratio of AUC derived from CLM to plasma lactate was 1.025 (0.990–1.058). Average dynamic delay time of CLM to venous plasma lactate was 5.22 min (2.87–10.35). Insertion sites examined 48 h after CLM removal did not show signs of side effects and none required medical attention upon examination. The newly developed CLM has shown to be a promising tool to continuously measure lactate concentration in a minimally invasive fashion. Results indicate the CLM can provide needed trends in lactate over time. Such a device may be used in the future to improve treatment in clinical conditions such as sepsis.
Laser Cladding Treatment for Refurbishing Disc Brake Rotors: Environmental and Tribological Analysis
Authors: Olofsson Ulf , Lyu Yezhe , Åström Anna Hedlund , Wahlström Jens , Dizdar Senad , Nogueira Ana Paula Gomes , Gialanella Stefano 
Published: April 2021

AbstractIn this study, grey cast iron disc brake rotors are refurbished by adding a surface layer through laser cladding. Current methods to deal with replaced rotors mainly include remelting, with a minority fraction disposed in landfill. Both approaches result in a huge waste of resources and an increase in CO2 footprint. From a sustainable point of view, this study aims to evaluate the feasibility of refurbishing brake rotors by a combined environmental and tribological performance approach. A streamlined life cycle assessment is conducted to compare the environmental impacts between producing virgin grey cast iron brake rotors and refurbishing replaced brake rotors by laser cladding. It turns out that the energy consumption and CO2 footprint of the laser cladding refurbished brake rotors are 80% and 90% less than the virgin brake rotors. The results show that the refurbished brake rotor yields higher friction compared to the original cast iron utilizing the same pad material. The wear and particle emissions of the disc brake contact are in this study higher for the laser-cladded one compared to the original cast iron one.
Adolescents’ selfie-taking and selfie-editing: A revision of the photo manipulation scale and a moderated mediation model
Authors: Gioia Francesca , McLean Siân , Griffiths Mark D. , Boursier Valentina 
Published: April 2021

Abstract‘Selfie practices’ (e.g., editing, filtering, sharing) have become adolescents’ daily behaviors. The increasing centrality of online visual self-presentation might increase adolescents’ appearance-related concerns, problematic monitoring, and photo manipulation (PM). However, few studies focused on body image control in photos (BICP) and PM, and no studies evaluated the influence of selfie-expectancies on photo-taking and photo-editing. Consequently, two studies were conducted. Study1 psychometrically evaluated the PM scale (N = 1353). Study2 evaluated the mediating role of BICP and the moderating role of gender in the relationship between selfie-expectancies and PM (N = 453). The revised PM scale showed good psychometric properties. BICP mediated the relationship between selfie-expectancies and PM and being male significantly affected the relationship between the variables. Implications for adolescents’ appearance-related issues are discussed.
Comment on “A Calibration‐Free Formulation of the Complementary Relationship of Evaporation for Continental‐Scale Hydrology” by J. Szilagyi et al.
Authors: Han Songjun , Tian Fuqiang 
Published: April 2021

AbstractSzilagyi et al. (2017) proposed an approach to accommodate Brutsaert's (2015) cubic complementary relationship model by scaling down its independent variable xB. This scaling down approach can work under a condition that xB is larger than its counterparts in the cubic equation, but decreases the performance of the model when xB is smaller than its counterparts.
The Arctic Subpolar Gyre sTate Estimate: Description and Assessment of a Data‐Constrained, Dynamically Consistent Ocean‐Sea Ice Estimate for 2002–2017
Authors: Nguyen An T. , Pillar Helen , Ocaña Victor , Bigdeli Arash , Smith Timothy A. , Heimbach Patrick 
Published: April 2021

AbstractA description and assessment of the first release of the Arctic Subpolar gyre sTate Estimate (ASTE_R1), a data‐constrained ocean‐sea ice model‐data synthesis, is presented. ASTE_R1 has a nominal resolution of 1/3° and spans the period 2002–2017. The fit of the model to an extensive (O(109)) set of satellite and in situ observations was achieved through adjoint‐based nonlinear least squares optimization. The improvement of the solution compared to an unconstrained simulation is reflected in misfit reductions of 77% for Argo, 50% for satellite sea surface height, 58% for the Fram Strait mooring, 65% for Ice Tethered Profilers, and 83% for sea ice extent. Exact dynamical and kinematic consistency is a key advantage of ASTE_R1, distinguishing the state estimate from existing ocean reanalyses. Through strict adherence to conservation laws, all sources and sinks within ASTE_R1 can be accounted for, permitting meaningful analysis of closed budgets at the grid‐scale, such as contributions of horizontal and vertical convergence to the tendencies of heat and salt. ASTE_R1 thus serves as the biggest effort undertaken to date of producing a specialized Arctic ocean‐ice estimate over the 21st century. Transports of volume, heat, and freshwater are consistent with published observation‐based estimates across important Arctic Mediterranean gateways. Interannual variability and low frequency trends of freshwater and heat content are well represented in the Barents Sea, western Arctic halocline, and east subpolar North Atlantic. Systematic biases remain in ASTE_R1, including a warm bias in the Atlantic Water layer in the Arctic and deficient freshwater inputs from rivers and Greenland discharge.
Interventional oncology: A snapshot of expanding practice
Authors: Khankan Azzam 
Published: April 2021

AbstractInterventional oncology (IO) was a minor part of interventional radiology. However, with the development of novel technologies and introduction of innovative therapeutics with dramatic transformations in the practice of oncology, IO is facing challenges in adopting and responding to these new changes to maintain its integral role and maximize its potentials in the efficient management of patients with cancer. In this snapshot, some of the novel therapeutic approach principles relevant to IO practice will be explained briefly.
Not Rocket Science: Implementing Efforts to Improve Working Conditions of Social Workers
Authors: Tham Pia 
Published: April 2021

Abstract
The aim of the study was to investigate if the working conditions of child welfare social workers in one municipality would be improved after the implementation of three initiatives: weekly small group supervision for newly educated social workers, team-strengthening activities and training for the team leaders. Five teams consisting of thirty-six child welfare social workers and five team leaders participated. At project start and after the two project years (2017–2018), the social workers’ perception of their working conditions was measured by a questionnaire (QPS Nordic). After the two years the social workers rated several aspects of their working conditions more positively. They were more satisfied with the organisational climate and leadership and with the collaboration in their work group. Turnover, which had been high for many years, had almost stopped and vacancies were now filled. The social workers were now more often satisfied with the quality of their work. Interestingly, these positive changes had occurred at the same time as the social workers now reported higher demands and more often experienced role conflicts. The overall results of this small-scale study indicate that working conditions of social workers can be improved after the implementation of rather modest means.
The Economic Consequences of Sir Robert Peel: A Quantitative Assessment of the Repeal of the Corn Laws
Authors: Irwin Douglas A , Chepeliev Maksym G 
Published: April 2021

Abstract
This paper provides a quantitative general equilibrium evaluation of the repeal of Britain's Corn Laws in 1846. Using a detailed input-output matrix of the British economy in 1841, we find the abolition of Britain's tariff on imported grain left overall welfare roughly unchanged as the static efficiency gains are offset by terms-of-trade losses. Labourers and capital owners gained a slight amount at the expense of landowners. Combining these changes in factor payments with the different consumption patterns across income groups, we find that the top 10% of income earners lost while the bottom 90% of income earners gained.
Heteroduplex DNA formation and homolog pairing in yeast meiotic mutants.
Authors: Nag D K , Scherthan H , Rockmill B , Bhargava J , Roeder G S 
Published: April 2021

Abstract
Previous studies of Saccharomyces cerevisiae have identified several meiosis-specific genes whose products are required for wild-type levels of meiotic recombination and for normal synaptonemal complex (SC) formation. Several of these mutants were examined in a physical assay designed to detect heteroduplex DNA (hDNA) intermediates in meiotic recombination. hDNA was not detected in the rec102, mei4 and hop1 mutants; it was observed at reduced levels in red1, mek1 and mer1 strains and at greater than the wild-type level in zip1. These results indicate that the REC102, MEI4, HOP1, RED1, MEK1 and MER1 gene products act before hDNA formation in the meiotic recombination pathway, whereas ZIP1 acts later. The same mutants assayed for hDNA formation were monitored for meiotic chromosome pairing by in situ hybridization of chromosome-specific DNA probes to spread meiotic nuclei. Homolog pairing occurs at wild-type levels in the zip1 and mek1 mutants, but is substantially reduced in mei4, rec102, hop1, red1 and mer1 strains. Even mutants that fail to recombine or to make any SC or SC precursors undergo a significant amount of meiotic chromosome pairing. The in situ hybridization procedure revealed defects in meiotic chromatin condensation in mer1, red1 and hop1 strains.
A Chlamydomonas genomic library in yeast artificial chromosomes.
Authors: Infante A , Lo S , Hall J L 
Published: April 2021

Abstract
We have constructed and characterized a Chlamydomonas reinhardtii total genomic library in yeast artificial chromosomes (YACs). The library contains 7500 clones with inserts ranging in size from 100-200 kb. The representation of the library was assessed by screening one-third of it with a probe derived from the dispersed repeat, Gulliver, which occurs approximately 13 times in the genome. At least 10 of these Gulliver loci were isolated within 15 independent YACs. Two of these YACs encompass the Gulliver element designated G, which was reported to map to the uni linkage group (ULG). The end clones of these two YACs have been genetically mapped by RFLP analysis in an interspecific cross and thereby shown to be closely linked to the APM locus on the ULG. A third uni-specific YAC has also been isolated and its ends have been mapped by RFLP analysis. Genetic and RFLP analysis of these and other YACs indicates that the frequency of chimeric YACs in the library is very low. The library was constructed in a second generation vector that enables plasmid rescue of YAC end clones as well as copy number amplification of artificial chromosomes. We provide evidence that amplification of intact YACs requires a rad1:rad52 yeast strain.