bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthetic RGB photometry of bright stars: definition of the standard photometric system and UCM library of spectrophotometric spectra
Authors: Cardiel Nicolás , Zamorano Jaime , Bará Salvador , Sánchez de Miguel Alejandro , Cabello Cristina , Gallego Jesús , García Lucía , González Rafael , Izquierdo Jaime , Pascual Sergio , Robles José , Sánchez Ainhoa , Tapia Carlos 
Published: April 2021

ABSTRACT
Although the use of RGB photometry has exploded in the last decades due to the advent of high-quality and inexpensive digital cameras equipped with Bayer-like colour filter systems, there is surprisingly no catalogue of bright stars that can be used for calibration purposes. Since due to their excessive brightness, accurate enough spectrophotometric measurements of bright stars typically cannot be performed with modern large telescopes, we have employed historical 13-colour medium-narrow-band photometric data, gathered with quite reliable photomultipliers, to fit the spectrum of 1346 bright stars using stellar atmosphere models. This not only constitutes a useful compilation of bright spectrophotometric standards well spread in the celestial sphere, the UCM library of spectrophotometric spectra, but allows the generation of a catalogue of reference RGB magnitudes, with typical random uncertainties ∼0.01 mag. For that purpose, we have defined a new set of spectral sensitivity curves, computed as the median of 28 sets of empirical sensitivity curves from the literature, that can be used to establish a standard RGB photometric system. Conversions between RGB magnitudes computed with any of these sets of empirical RGB curves and those determined with the new standard photometric system are provided. Even though particular RGB measurements from single cameras are not expected to provide extremely accurate photometric data, the repeatability and multiplicity of observations will allow access to a large amount of exploitable data in many astronomical fields, such as the detailed monitoring of light pollution and its impact on the night sky brightness, or the study of meteors, Solar system bodies, variable stars, and transient objects. In addition, the RGB magnitudes presented here make the sky an accessible and free laboratory for the calibration of the cameras themselves.
Accurate 3D fireball trajectory and orbit calculation using the 3D-firetoc automatic Python code
Authors: Peña-Asensio Eloy , Trigo-Rodríguez Josep Maria , Gritsevich Maria , Rimola Albert 
Published: April 2021

ABSTRACT
The disruption of asteroids and comets produces cm-sized meteoroids that end up impacting the Earth’s atmosphere and producing bright fireballs that might have associated shock waves or, in geometrically favourable occasions excavate craters that put them into unexpected hazardous scenarios. The astrometric reduction of meteors and fireballs to infer their atmospheric trajectories and heliocentric orbits involves a complex and tedious process that generally requires many manual tasks. To streamline the process, we present a software package called SPMN 3D Fireball Trajectory and Orbit Calculator (3D-firetoc), an automatic Python code for detection, trajectory reconstruction of meteors, and heliocentric orbit computation from video recordings. The automatic 3D-firetoc package comprises of a user interface and a graphic engine that generates a realistic 3D representation model, which allows users to easily check the geometric consistency of the results and facilitates scientific content production for dissemination. The software automatically detects meteors from digital systems, completes the astrometric measurements, performs photometry, computes the meteor atmospheric trajectory, calculates the velocity curve, and obtains the radiant and the heliocentric orbit, all in all quantifying the error measurements in each step. The software applies corrections such as light aberration, refraction, zenith attraction, diurnal aberration, and atmospheric extinction. It also characterizes the atmospheric flight and consequently determines fireball fates by using the α − β criterion that analyses the ability of a fireball to penetrate deep into the atmosphere and produce meteorites. We demonstrate the performance of the software by analysing two bright fireballs recorded by the Spanish Fireball and Meteorite Network (SPMN).
E. coli RNase I exhibits a strong Ca2+-dependent inherent double-stranded RNase activity
Authors: Grünberg Sebastian , Coxam Baptiste , Chen Tien-Hao , Dai Nan , Saleh Lana , Corrêa Ivan R , Nichols Nicole M , Yigit Erbay 
Published: April 2021

Abstract
Since its initial characterization, Escherichia coli RNase I has been described as a single-strand specific RNA endonuclease that cleaves its substrate in a largely sequence independent manner. Here, we describe a strong calcium (Ca2+)-dependent activity of RNase I on double-stranded RNA (dsRNA), and a Ca2+-dependent novel hybridase activity, digesting the RNA strand in a DNA:RNA hybrid. Surprisingly, Ca2+ does not affect the activity of RNase I on single stranded RNA (ssRNA), suggesting a specific role for Ca2+ in the modulation of RNase I activity. Mutation of a previously overlooked Ca2+ binding site on RNase I resulted in a gain-of-function enzyme that is highly active on dsRNA and could no longer be stimulated by the metal. In summary, our data imply that native RNase I contains a bound Ca2+, allowing it to target both single- and double-stranded RNAs, thus having a broader substrate specificity than originally proposed for this traditional enzyme. In addition, the finding that the dsRNase activity, and not the ssRNase activity, is associated with the Ca2+-dependency of RNase I may be useful as a tool in applied molecular biology.
Liquidity traps in a monetary union
Authors: Kollmann Robert 
Published: April 2021

Abstract
The closed economy macro literature has shown that a liquidity trap can result from the self-fulfilling expectation that future inflation and output will be low. This paper investigates expectations-driven liquidity traps in a two-country New Keynesian model of a monetary union. In the model here, a rise in government purchases in an individual country has a weak effect on GDP in the rest of the union. The results here cast doubt on the view that, in the current era of ultra-low interest rates, a rise in fiscal spending by Euro Area (EA) core countries would significantly boost GDP in the EA periphery.
Clinical Presentation, Management, and Outcomes of Patients With Brain Abscess due to Nocardia Species
Authors: Corsini Campioli Cristina , Castillo Almeida Natalia E , O’Horo John C , Challener Douglas , Go John Raymond , DeSimone Daniel C , Sohail M Rizwan 
Published: April 2021

Abstract

Background
Nocardial brain abscesses are rare, and published literature describing brain abscesses due to Nocardia species is limited to individual case reports or small series. We report one of the largest contemporary retrospective studies describing risk factors, diagnostic evaluation, management, and outcomes of nocardial brain abscess.

Methods
Retrospective review of all adults with brain abscess due to culture-confirmed Nocardia species at our institution between January 1, 2009, and June 30, 2020.

Results
Overall, 24 patients had nocardial brain abscesses during the study period. The median age at presentation was 64 years, and 62.5% were immunocompromised. Pulmonary and cutaneous infections were the most common primary sites of nocardial infection. All 24 patients had magnetic resonance imaging performed, and the frontal lobe was the most commonly involved. The most common organism isolated was Nocardia farcinica, followed by Nocardia wallacei and Nocardia cyriacigeorgica. Thirteen patients were managed with antimicrobial therapy alone, while 11 had both medical and surgical management. In all patients, dual therapy was recommended for the initial 6 weeks of treatment, and 22 patients received at least 1 oral agent as part of their final antibiotic regimen, predominantly trimethoprim-sulfamethoxazole and linezolid. Fourteen patients achieved complete clinical and radiographic resolution of infection.

Conclusions
Nocardia is an important cause of brain abscess in the immunocompromised host. Early diagnostic and therapeutic aspiration may help health care providers confirm the diagnosis, choose an appropriate antimicrobial regimen, and achieve source control.
Vertical changes in abundance, biomass and community structure of pelagic polychaetes down to 1000 m depths at Station K2 in the western subarctic Pacific Ocean covering the four seasons and day–night
Authors: Amei Kanako , Dobashi Ryo , Jimi Naoto , Kitamura Minoru , Yamaguchi Atsushi 
Published: April 2021

Abstract
Pelagic polychaetes are distributed from the sea surface to greater depths of the oceans worldwide, but little information is available regarding their ecology. This study investigated the vertical distribution of abundance, biomass and community structure of pelagic polychaetes at a single station in the western subarctic Pacific based on day–night vertical stratified samples collected from a 0 to 1000 m water column during four seasons covering 1 year. The polychaete abundance and biomass ranged from 0 to 757 ind. 1000 m−3 and 0–6.1 mg WW m−3, respectively. Ten pelagic polychaete species belonging to nine genera and six families were identified. From cluster analysis based on abundance, the polychaete community was divided into five communities. Each community occurred at different depth layers. Two surface groups seen at 0–200 m were dominated by two carnivorous species: Tomopteris septentrionalis and Typhloscolex muelleri. The deepest group, dominated by the particle feeder Pelagobia longicirrata, was seen at 500–1000 m. Two transition groups occurred in the intermediate depths. These vertical distributions of the pelagic polychaete communities were common throughout the season and day. Water mass, food availability and the oxygen minimum layer are put forth as environmental factors that affect the pelagic polychaete community.
Can Craniometry Play a Role in Cluster Headache Diagnosis? A Pilot Exploratory TC-3D Based Study
Authors: Russo Antonio , Silvestro Marcello , Vanore Laura , Capasso Raffaella , Siciliano Mattia , Tessitore Alessandro , Caranci Ferdinando , Tedeschi Gioacchino , Conforti Renata 
Published: April 2021

Abstract

Background
Since the pioneering reports of the so-called leonine face in cluster headache (CH) patients, cranial and facial features of these patients have been poorly investigated with conflicting results. We aimed to investigate whether abnormalities in craniometric measurements could characterize male CH patients and represent reliable and reproducible diagnostic biomarkers able to identify CH patients.

Methods
Brain CT images were recorded between 2018 and 2020 in 24 male patients with CH and in 24 matched healthy controls (HC). Then, craniometric measurements were obtained, and logistic regression and receiver operating characteristic curves analyses were used to identify the craniometric abnormalities able to distinguish CH patients from HC.

Results
Logistic regression analyses showed that frontal bone height and facial width were able to discriminate, one independently from the other, CH patients from HC with an overall accuracy of 77%. The optimal cutoff score in detecting the probable presence of CH was 11.50 cm for frontal bone height and 13.30 cm for facial width.

Discussion
In the present study we found, for the first time by means of brain 3D computed tomography approach, abnormal craniometric measurements in CH patients when compared with HC. The absence of differences in smoke and alcohol intake suggests that the observed craniometric abnormalities may represent a specific feature of CH patients.

Conclusion
The craniometric evaluation by means of brain 3D computed tomography could represent a widespread, noninvasive, and accurate tool to support CH diagnosis to avoid frequent misdiagnosis or delay in the diagnostic process.
Do Corticosteroid Injections for the Treatment of Pain Influence the Efficacy of Adenovirus Vector-Based COVID-19 Vaccines?
Authors: Lee Haewon , Punt Jennifer A , Patel Jaymin , Stojanovic Milan P , Duszynski Belinda , McCormick Zachary L ,   the Spine Intervention Society’s Patient Safety Committee
Published: April 2021

Abstract

Myth
Corticosteroid injection for the treatment of pain is known to decrease the efficacy of the adenovirus vector-based vaccines for COVID-19.

Fact
There is currently no direct evidence to suggest that a corticosteroid injection before or after the administration of an adenovirus vector-based COVID-19 vaccine decreases the efficacy of the vaccine. However, based on the known timeline of hypothalamic-pituitary-adrenal axis suppression following epidural and intraarticular corticosteroid injections, and the timeline of the reported peak efficacy of the Janssen and AstraZeneca vaccines, physicians should consider timing an elective corticosteroid injection such that it is administered no less than 2 weeks prior to and no less than 2 weeks following a COVID-19 adenovirus vector-based vaccine dose, whenever possible. We emphasize the importance of risk/benefit analysis and shared decision making in determining the timing of corticosteroid injections for pain indications in relation to receipt of a COVID-19 vaccine given that patient-specific factors will vary.
Personal Wealth, Self-Employment, and Business Ownership
Authors: Bellon Aymeric , Cookson J Anthony , Gilje Erik P , Heimer Rawley Z 
Published: April 2021

Abstract
We study the effect of personal wealth on entrepreneurial decisions using data on mineral payments from Texas shale drilling to individuals throughout the United States. Large cash windfalls increase business formation by 0.8 to 2.1 percentage points, but do not affect transitions to self-employment. By contrast, cash windfalls significantly extend self-employment spells, but do not affect the duration of business ownership. Our findings help reconcile contrasting findings in prior work: liquidity constraints have different effects on entrepreneurial activity that may depend on the entrepreneur’s motivations.
Resolution of vascular inflammation in patients with new-onset giant cell arteritis: data from the RIGA study
Authors: Schönau Verena , Roth Jessica , Tascilar Koray , Corte Giulia , Manger Bernhard , Rech Juergen , Schmidt Daniela , Cavallaro Alexander , Uder Michael , Crescentini Filippo , Boiardi Luigi , Casali Massimiliano , Spaggiari Lucia , Galli Elena , Kuwert Torsten , Versari Annibale , Salvarani Carlo , Schett Georg , Muratore Francesco 
Published: April 2021

Abstract

Objectives
Efficacy evaluation of GCA treatment is primarily based on non-specific symptoms and laboratory markers. We aimed to assess the change in vascular inflammation in patients with large vessel (LV)-GCA under different treatments using [18F]FDG PET/CT.

Methods
Observational study on patients with new-onset, active LV-GCA starting treatment with either prednisolone monotherapy (PRED) or combination with MTX or tocilizumab (TOC). All patients underwent baseline and follow-up PET/CT. The aorta and its major branches were assessed using PET vascular activity score (PETVAS) by independent readers. Cumulative glucocorticoid doses and cessation of glucocorticoid treatment were documented in all patients.

Results
We included 88 LV-GCA patients, 27 were treated with PRED, 42 with MTX and 19 with TOC. PETVAS decreased from 18.9–8.0 units at follow-up in the overall population (P &lt;0.001). PETVAS changes were numerically higher in patients receiving MTX (−12.3 units) or TOC (−11.7 units) compared with PRED (−8.7). Mean cumulative prednisolone dosages were 5637, 4418 and 2984 mg in patients treated with PRED, MTX and TOC (P =0.002). Risk ratios for glucocorticoid discontinuation at the time of follow-up PET/CT were 6.77 (95% CI: 1.01, 45.29; P =0.049) and 16.25 (95% CI: 2.60, 101.73; P =0.003) for MTX and TOC users compared with PRED users.

Conclusion
Treatment of LV-GCA inhibits vascular inflammation in the aorta and its major branches. While similar control of vascular inflammation was achieved with PRED, MTX and TOC treatments, TOC showed a strong glucocorticoid sparing effect, supporting the concept of initial combination therapy.
Acute Kidney Injury Recovery Patterns in Critically Ill Patients: Results of a Retrospective Cohort Study*
Authors: Abdel-Nabey Moustafa , Ghrenassia Etienne , Mariotte Eric , Valade Sandrine , Morel Guillaume , Lemiale Virginie , Zafrani Lara , Azoulay Elie , Darmon Michael 
Published: April 2021

OBJECTIVES:
Acute kidney injury, acute kidney injury severity, and acute kidney injury duration are associated with both short- and long-term outcomes. Despite recent definitions, only few studies assessed pattern of renal recovery and time-dependent competing risks are usually disregarded. Our objective was to describe pattern of acute kidney injury recovery, change of transition probability over time and their risk factors.

DESIGN:
Monocenter retrospective cohort study. Acute kidney injury was defined according to Kidney Disease Improving Global Outcomes definition. Renal recovery was defined as normalization of both serum creatinine and urine output criteria. Competing risk analysis, time-inhomogeneous Markov model, and group-based trajectory modeling were performed.

SETTING:
Monocenter study.

PATIENTS:
Consecutive patients admitted in ICU from July 2018 to December 2018 were included.

INTERVENTIONS:
None.

MEASUREMENTS AND MAIN RESULTS:
Three-hundred fifty patients were included. Acute kidney injury occurred in 166 patients at ICU admission, including 64 patients (38.6%) classified as acute kidney disease according to Acute Disease Quality Initiative definition and 44 patients (26.5%) who could not be classified. Cumulative incidence of recovery was 25 % at day 2 (95% CI, 18–32%) and 35% at day 7 (95% CI, 28–42%). After adjustment, need for mechanical ventilation (subdistribution hazard ratio, 0.42; 95% CI, 0.23–0.74) and severity of the acute kidney injury (stage 3 vs stage 1 subdistribution hazard ratio, 0.11; 95% CI, 0.03–0.35) were associated with lack of recovery. Group-based trajectory modeling identified three clusters of temporal changes in this setting, associated with both acute kidney injury recovery and patients’ outcomes.

CONCLUSIONS:
In this study, we demonstrate Acute Disease Quality Initiative to allow recovery pattern classification in 75% of critically ill patients. Our study underlines the need to take into account competing risk factors when assessing recovery pattern in critically ill patients.
Exhalation Spreading During Nasal High-Flow Therapy at Different Flow Rates
Authors: Dellweg Dominic , Kerl Jens , Gena Amayu Wakoya , Alsaad Hayder , Voelker Conrad 
Published: April 2021

OBJECTIVES:
Severe acute respiratory syndrome coronavirus 2 is transmitted through aerosols and droplets. Nasal high-flow therapy could possibly increase the spreading of exhalates from patients. The aim of this study is to investigate whether nasal high-flow therapy affects the range of the expiratory plume compared with spontaneous breathing.

DESIGN:
Interventional experiment on single breaths of a healthy volunteer.

SETTING:
Research laboratory at the Bauhaus-University Weimar.

Subjects:
A male subject.

INTERVENTIONS:
Videos and images from a schlieren optical system were analyzed during spontaneous breathing and different nasal high-flow rates.

MEASUREMENTS AND MAIN RESULTS:
The maximal exhalation spread was 0.99, 2.18, 2.92, and 4.1 m during spontaneous breathing, nasal high-flow of 20 L/min, nasal high-flow of 40 L/min, and nasal high-flow of 60 L/min, respectively. Spreading of the expiratory plume in the sagittal plane can completely be blocked with a surgical mask.

CONCLUSIONS:
Nasal high-flow therapy increases the range of the expiratory air up to more than 4 meters. The risk to pick up infectious particles could be increased within this range. Attachment of a surgical mask over the nasal high-flow cannula blocks the expiratory airstream.
An Unusual Complication following Gluteal Fat Grafting: A Case Report
Authors: Neiman Ariel , Sadeh Omer , Dudaie Shay , Shoufani Aziz 
Published: April 2021

Summary:
Subfascial abscess of the lateral thigh is a relatively uncommon complication following gluteal fat grafting due to their subclinical presentation. Despite its rarity, subfascial abscesses can be dangerous and life-threatening when diagnosis is delayed. In this case report, we present a 28-year-old woman who presented to our hospital with swelling and erythema following a gluteal fat grafting procedure performed abroad. Our initial treatment which included transcutaneous drainage and systemic antibiotics was unsuccessful. This conservative approach was influenced by the patient’s initial procedure and attempt to conserve aesthetic appearance. The severity of the complication was not entirely known until advanced radiological imaging (computer tomography imaging) was performed several days after hospitalization and revealed large subfascial abscess. Surgical drainage with fasciotomy was required due to a persisting high fever and fluid accumulation in the lateral thigh. Approximately 1 L of purulent fluid was collected, containing large bulks of fat particles and blood clots that drained from the subfascial space. The wound was left open and treated with vacuum-assisted closure. Direct penetration of cannula through fascial layer, insertion of harvested fat that exceeds intrinsic properties of fascia, or unknown intercompartment connections can lead to deep subfascial migration of fat. Aggressive measures that include immediate advanced radiological imaging should be performed when the severity of damage and migration of injected fat are unknown. Transcutaneous drainage is not effective for subfascial abscesses due to formation of large fat particles and blood clots that cannot be drained. Immediate incision and drainage should be considered for similar cases.
The comparison of ketamine with tramadol for postoperative pain relief on children following adenotonsillectomy or tonsillectomy
Authors: Wang Lifeng , Guo Yongkang , Tian Jun 
Published: April 2021

Abstract

Introduction:
The comparison of ketamine with tramadol for pain control remains controversial in pediatric adenotonsillectomy or tonsillectomy. We conduct a systematic review and meta-analysis to explore the efficacy of ketamine vs tramadol for pain relief in children following adenotonsillectomy or tonsillectomy.

Methods:
We have searched PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases through October 2019 for randomized controlled trials (RCTs) assessing the effect of ketamine vs tramadol for pediatric adenotonsillectomy or tonsillectomy. This meta-analysis is performed using the random-effects model.

Results:
Six RCTs are included in the meta-analysis. Overall, compared to ketamine group for pediatric adenotonsillectomy or tonsillectomy, tramadol is associated with substantially lower CHEOPS at 1 h (SMD = 1.56; 95% CI = 0.20–2.92; P = .02; low quality) and longer first time of additional pain medication (SMD = −0.47; 95% CI = −0.74 to −0.19; P = .0008; low quality), but demonstrates no obvious effect on CHEOPS at 6 h (SMD = 0.51; 95% CI = −1.17 to 2.19; P = .55; low quality), sedation scale at 1 h (SMD = −0.80; 95% CI = −3.07 to 1.48; P = .49; low quality) or additional pain medication (RR = 1.31; 95% CI = 0.85–2.02; P = .23; moderate quality).

Conclusions:
Tramadol may be better to alleviate the postoperative pain after pediatric adenotonsillectomy or tonsillectomy.