bluuebunny/crossref_metadata_2025_split huggingface dataset:
Des situations potentielles d’apprentissage dans l’évolution du travail d’enseignants
Authors: Mayen Patrick 
Published: March 2021

Cet article aborde un aspect spécifique – mais courant – du travail des enseignants en formation professionnelle : les difficultés scolaires. Il examine comment des initiatives prises par des enseignants pour répondre aux difficultés qu’ils éprouvent avec les difficultés de leurs élèves ou apprentis, les amène à découvrir et à redécouvrir un certain nombre de points aveugles de leur travail avec les élèves ou les apprentis et l’activité des élèves et apprentis. Il montre aussi comment ces découvertes, et les apprentissages qui en résultent, peuvent être développés par une mise en relation de ces découvertes avec quelques conceptualisations proposées à partir d’une analyse de leur expérience et de celle des élèves.
Quelle activité pour le formateur dans une situation d’apprentissage d’une activité instrumentée ?
Authors: Petit Lucie 
Published: March 2021

Cet article s’intéresse à l’activité de formateurs lors d’un cours sur l’utilisation des Tice d’une première année de Master « Métiers de la formation ». L’intervention des formateurs observés s’organise en cours d’action, au gré de l’activité productive (Samurçay et Rabardel, 2004) de 10 équipes d’étudiants qui apprennent à monter un ou plusieurs films courts. Le but de la situation d’apprentissage n’est pas de former des professionnels de l’audiovisuel mais de préparer de futurs spécialistes de la formation à l’élaboration d’un produit multimédia éducatif. Dès lors, comment caractérìser l’activité des formateurs ? Le fait qu’elle se déploie en cours d’action lors de travaux dirigés et s’ajuste aux difficultés rencontrées, l’inscrit-elle dans le registre de l’accompagnement plutôt que dans celui de la transmission ? Dans de telles conditions, comment sont traités les contenus, entendus comme les savoirs et savoir-faire nécessaires pour réaliser une tâche et en résoudre les problèmes ?
Experience with FLT3 Inhibitor Midostaurin in Newly Diagnosed Acute Myeloid Leukemia Patients
Authors: BAYSAL Mehmet , ALKİS Nihan , BAYSAL Serap 
Published: March 2021

Introduction With the introduction of FLT3 inhibitors in recent years, the presence of FLT3 mutation in newly diagnosed acute myeloid leukemia (AML) patients has become more important. it was observed that the addition of Midostaurin to remission induction and consolidation chemotherapy, brought a 22% reduction in mortality risk in patients with FLT3 mutation. In the light of the above information, we aimed to share our experience regarding the use of Midostaurin in our newly diagnosed AML patients.
Methods The data of 20 patients who were diagnosed with AML between April 2020 and November 2020 in the Hematology Department of Bursa City Hospital and who were eligible for standard remission induction therapy were evaluated retrospectively. Standard remission induction chemotherapy consisting of a combination of cytosine arabinoside (ARA-C) and an anthracycline was applied to patients. Consolidation treatment with high dose ARA-C was given to patients in remission; Midosaturin 100 mg was added to High-dose ARA-C between days 8 and 21 in patients with FLT3 mutation.
Results: Twenty patients included in the study, 14 were men and 6 were women. There were six patients with the FLT3 mutation. Five patients with FLT3 mutation were male and one was female. The mean age of the patients is 53.8; the mean age of the patients with FLT 3 mutation was 49.8 years. Two patients with FLT 3 mutation died due to sepsis during remission induction treatment; In Four patients, complete response was obtained with remission induction therapy. Four patients had been given midostaurin with high dose ARA-C and referred for bone marrow transplantation.
Conclusion The use of FLT3 inhibitors in combination with chemotherapeutic agents in the treatment of AML patients with FLT3 mutation is considered as a standard. However, it takes a certain amount of time for the FLT3 mutation to result. For this reason, Midostaurin treatment could be added not during remission induction but consolidation. Although our study included a limited number of patients it shows the importance of Midostaurin treatment in newly diagnosed AML patients with FLT3 mutation as real-world data.
Prognostic biomarkers in lung cancer patients in terms of long-term survival
Authors: COSKUN Belkis Nihan , DİZDAR Oğuzhan Sıtkı , KORKMAZ Şeniz , ULUKAYA Engin , EVRENSEL Türkkan 
Published: March 2021

Introduction:
We aimed to investigate the predictive effect of serum M30 and M65 antigens on long-term prognosis in patients with advanced stage lung cancer before and after the first dose of chemotherapy.
Methods:
Fourty eight patients with advanced stage lung cancer were included in the study. Demographic data and histopathological characteristics of the patients were recorded. Serum levels of M30 and M65 were studied in 48 patients before chemotherapy, and in 43 patients both before and 48 hours after chemotherapy. Long-term survival was evaluated using Kaplan-Meier curves. The effect of high or low M30, M65 levels and M30/M65 ratio on long-term survival was investigated.
Results: The mean age of the patients at the time of diagnosis was 57.52 ± 9.38 years. Fourty six of the 48 patients were men. While M30 value before chemotherapy was 163.23 ± 112.30 U/l; It was measured as 249.74 ± 266.67 U/l 48 hours after chemotherapy (p
The Art Group Crit. How do you make a Firing Squad Less Scary
Authors: Day Peter 
Published: March 2021

The relationship between achievement and feedback and the fact that effective feedback improves achievement is well documented (Taylor and McCormack, 2004; Hattie, 2007). This is especially true of written feedback.ÃÂ However in art and design education feedback will take place in an often emotionally charged face-to-face meeting where verbal criticism, both negative and positive, takes place in front of an audience. The forum for this feedback in art education is the Group Crit (Crit, Art Crit, or Group Critique) at which students are expected to present and perform. It is the studentsÃ¢â¬â¢ reception and perception of this oral feedback in todayÃ¢â¬â¢s quality-focused context, which is at the heart of this study. This article presents a study into the impact of verbal feedback on achievement in art and design education via a survey taken amongst 60 undergraduate art and design students, at the University of Institution in 2009/10. The survey collected both quantitative and qualitative responses and identified a fundamentally emotional and fear-focused perception of the Group Crit, one opposed to its supportive and bespoke dynamic intentions. A stress factor (Pope, 2005; Anthony, 1991) is created when personalised feedback is perceived as a negative (critical) reflection on the student performance (at the Crit), their self worth and esteem and not the work presented. Criticism, and by implication feedback, is perceived as negative, personal and subjective and fraught with contradiction and loss of Ã¢â¬ËrespectÃ¢â¬â¢ - in opposition to the studentsÃ¢â¬â¢ previous prescriptive and Ã¢â¬ËobjectiveÃ¢â¬â¢ educational experiences.
Functional Rejuvenation of Recurrent Laryngeal Nerve after Excision of Parathyroid Cyst: A Case Report and Systematic Review of Literature
Authors: Sharma Priyanka , Sharma Manoj , Reddy N Vishnu S , Chintham Murali 
Published: March 2021

ABSTRACT
Vocal fold paralysis is a prevalent manifestation of various disorders inclusive of the commonest conditions, such as, cardiothoracic surgeries, head and neck malignancies, whereas parathyroid cysts and cervical osteophytes are the rarest causes of this common presentation.
A comprehensive systematic review of the literature was done with keyword “parathyroid cysts causing vocal fold palsy” using MEDLINE, PubMed, additionally following PRISMA 2009 guidelines.
A 59-year-old male patient presented with hoarseness of voice with right-sided neck swelling for one year. Excision of swelling adherent to the carotid sheath was done. Postoperative histopathological and biochemical analysis of aspirated fluid was consistent with the parathyroid cyst.
Patient is in regular follow-up, and there are no clinical signs of recurrence and there is normal functioning of the affected vocal cord. This report adds to the growing knowledge of rare parathyroid cysts with unusual presentations, along with an understanding of pathophysiology, clinical diagnosis, and recovery options for vocal fold palsy due to lesions in the parathyroid gland.
How to cite this article: Reddy NVS, Sharma M, Chintham M, et al. Functional Rejuvenation of Recurrent Laryngeal Nerve after Excision of Parathyroid Cyst: A Case Report and Systematic Review of Literature. Int J Otorhinolaryngol Clin 2020;12(2):31–34.
Evaluasi Sistem Pengendalian Intern Penerimaan dan Pengeluaran Kas untuk Organisasi Non Profit (Studi Empiris pada Jemaat GPM Amahusu)
Authors: NATEN SIMSON 
Published: March 2021

Gereja-gereja memiliki pemahamanan prinsip dan pola pelayanan bergereja yang berbeda terutama dalam pengembangan dan penerapan pengendalian internnya. Sehingga gereja di perhadapakan pada masalah Pemanfaatan kas dalam menjalankan aktifitasnya. Kondisi ini memungkinkan kas berpotensi terhadap kesalahan pencatatan, penyimpangan maupun penyalahgunaan yang tidak sesuai dengan prosedur. Karena itu untuk menghasilkan suatu informasi akuntansi yang baik dibutuhkan pengendalian intern yang baik, harus di bentuk suatu fungsi yang baik pula untuk mengawasi penerimaan dan pengeluaran kas melalui pencatatan akuntansi. Penelitian ini bertujuan untuk mengetahui penerapan pengendalian intern yang dijalankan oleh Gereja Protestan Maluku khususnya Jemaat GPM Amahusu Klasis Pulau Ambon, apakah penerapan pengendalian intern terhadap penerimaan dan pengeluaran kas yang dilakukan sudah sesuai teori akuntansi yang ada. Metode penelitian yang digunakan dalam penelitian ini, adalah dengan wawancara, observasi dan dokumentasi. Teknik analisis data yang digunakan dalam penelitian ini adalah: (1) Mendeskripsikan pengendalian intern penerimaan dan pengeluaran kas terhadap struktur organisasi, system otorisasi, prosedur pencatatan, serta praktik yang dijalankan oleh Gereja Protestan Maluku Jemaat Amahusu. (2) Menguji dan menganalisis penerapan sistem pengendalian intern penerimaan dan pengeluaran kas pada Jemaat GPM Amahusu apakah sudah berjalan efektif. 3. Melihat bagaimana bentuk system pengendalian intern terhadap penerimaan dan pengeluaran kas Jemaat GPM Amahusu sudah berjalan efektif. Berdasarkan hasil analisa yang telah dilakukan, dapat disimpulkan bahwa pelaksanaan pengendalian intern penerimaan dan pengeluaran kas yang dilakukan gereja-gereja di Rayon Bantul masih terdapat beberapa hal yang belum sesuai dengan Sisitem Pengendalian Interen (SPI), tetapi telah disesuaikan dengan kondisi yang ada dalam gereja. Beberapa hal yang kurang sesuai adalah dalam hal pemisahan fungsi yang dalam praktiknya belum dilakukan secara tegas, otoritas dan adanya nomor bukti yang tidak tercetak.
Efektifitas Penerapan Program E-Tilang Dalam Mewujudkan Penegakan Hukum Lalu Lintas
Authors: Bakri Bakri , Nuh Muhammad Syarif , Badaru Baharuddin 
Published: March 2021

Penelitian ini bertujuan untuk Menganalisis efektifitas penerapan program e-tilang dalam mewujudkan penegakan hukum lalu lintas di Wilayah Hukum Polres Bone, serta faktor-faktor apa sajakah yang mempengaruhi upaya penegakan hukum berlalu lintas melalui program e-tilang. Berdasarkan analisis terhadap data dan fakta penulis berkesimpulan bahwa penerapan program e-tilang sudah cukup efektif dalam mewujudkan penegakan hukum lalu lintas bebas korupsi di Wilayah Hukum Polres Bone. Hal ini dapat dilihat melalui peningkatan jumlah pelanggaran yang terjadi antara tahun 2016 ke tahun 2017 yang meningkat secara signifikan. Hal ini menunjukkan bahwa program e-tilang sangat efisien dan cukup efektif menekan angka pungli. Pada sistem e-tilang, oknum tidak dapat lagi melakukan negosiasi terkait dengan pelanggaran lalu lintas, karena sudah tercatat secara digital dan harus selesai sampai dengan adanya putusan pengadilan. Faktor-faktor apa sajakah yang mempengaruhi upaya penegakan hukum berlalu lintas melalui program e-tilang di Wilayah Hukum Polres Bone meliputi Faktor hukum, Faktor penegak hukum, Faktor sarana, Faktor masyarakat, dan Faktor kebudayaan.
This study aims to analyze the effectiveness of the application of the e-ticketing program in realizing traffic law enforcement in the Bone Police Legal Area, as well as what factors influence the effort to enforce traffic law through the e-ticketing program. Based on an analysis of the data and facts, the author concludes that the application of the e-ticketing program has been quite effective in realizing the enforcement of corruption-free traffic law in the Bone Police Legal Area. This can be seen through the increase in the number of violations that occurred between 2016 and 2017 which increased significantly. This shows that the e-ticketing program is very efficient and quite effective at reducing extortion rates. In the e-ticketing system, the person can no longer conduct negotiations related to traffic violations, because it has been digitally recorded and must be finished until a court decision is made. What factors influence traffic law enforcement efforts through the e-ticketing program in the Bone Police Regional Law Area include legal factors, law enforcement factors, facility factors, community factors, and cultural factors.
Potensi Daerah,Promosi, Sarana dan Prasarana Berpengaruh Terhadap Keputusan Berkunjung Wisatawan Mancanegara dan Implikasinya Terhadap Strategi Segmentasi dan Positioning
Authors: Husna Syah St. Asmaul , Juniar Ahmad Gani Pratiwi 
Published: March 2021

Tujuan penelitian ini untuk menjelaskan 1) obyek wisata berpengaruh terhadap keputusan berkunjung wisatawan mancanegara; 2) promosi berpengaruh terhadap keputusan berkunjung wisatawan mancanegara; 3) sarana dan prasarana berpengaruh terhadap keputusan berkunjung wisatawan mancanegara; 4) faktor eksternal berpengaruh terhadap keputusan berkunjung wisatawan mancanegara; 5) segmen-segmen pasar wisata diidentifkasi berdasarkan persepsi wisatawan terhadap manfaat yang dicari; 6) terdapat hubungan yang bermakna antara sejumlah variabel deskriptor (segmen descriptor) dengan segmentasi pasar wisata Sulawesi Selatan; 7) implikasi dari masing-masing segmen pasar wisata terhadap strategi penentuan pasar sasaran (targeting) dan strategi memposisikan (positioning) daerah tujuan wisata di Sulawesi Selatan. Penelitian ini mengkaji hubungan antar variabel sehingga termasuk dalam explanatory research. Lokasi penelitian ini adalah daerah tujuan wisata Sulawesi Selatan dengan target populasi wisatwan mancanegara. Ada tiga Kabupaten/kota yang dipilih sebagai daerah tujuan wisata. Populasi penelitian adalah wisatawan mancanegara yang datang berkunjung pada daerah tujuan wisata di kabupaten/kota yaitu sebanyak 165 orang. Analisis Statistik yang digunakan adalah analisis regresi, analisis factor, dan analisis cluster. Hasil penelitian menunjukkan bahwa: 1) atraksi wisata, promosi, sarana dan prasarana serta factor eksternal mempunyai pengaruh secara signifikan terhadap variabel keputusan berkunjung; 2) dari 34 manfaat yang dicari terbentuk 10 faktor daya tarik wisata; 3) dari 165 kasus yang diungkap terbentuk 4 segmen pasar yang potensial bagi daerah tujuan wisata Sulawesi Selatan; 4) persepsi wisatawan mengenai posisi daerah tujuan wisata Sulawesi Selatan terhadap para pesaing utamanya dan harapan para wisatawannya sebelum datang ke Sulawesi Selatan, secara umum di benak pasarnya Sulawesi Selatan ternyata paling ideal diposisikan (positioning) sebagai daerah tujuan wisata etnis dan pantai (beach destination). Akan tetapi mengingat besarnya potensi pasar dari kedua segmen pasar yang lainnya, kedua segmen pasar wisata tersebut perlu dipertimbangkan untuk diraih sebagai sasaran pemasaran (target markets) dengan upaya-upaya mereposisikannya (repositioning).
Wolf reintroduction to Scotland could support substantial native woodland expansion and associated carbon sequestration
Authors: Spracklen D. V. , Chapman P. J. , Fletcher T. , Lane J. V. , Nilsen E. B. , Perks M. , Schofield L. , Scott C. E. 
Published: February 2025

Abstract

Large carnivores, including the grey wolf (Canis lupus), play an important role in the carbon cycle through modifying the behaviour and population of wild herbivores. Large carnivores have been eradicated from much of their former range and are now absent from the UK, contributing to increased herbivore populations, which can prevent natural regeneration of trees and woodland. A reintroduction of wolves to the UK could reduce deer populations and associated browsing of tree saplings, but the potential impacts on woodland expansion and carbon sequestration have not been assessed.

Here we estimate the impact of a wolf reintroduction in the Scottish Highlands on red deer populations, native woodland colonisation and carbon sequestration. We use a Markov predator–prey model to estimate that a reintroduction would lead to a population of 167 ± 23 wolves, sufficient to reduce red deer populations below 4 deer km−2, the threshold at which we assume browsing to be sufficiently suppressed to enable natural colonisation of trees.

Using a model of potential new native woodlands we estimate the subsequent expansion of native woodland would result in an average annual carbon sequestration of 1.0 ± 0.1 Mt CO2, with each wolf contributing an annual carbon sequestration of 6080 t CO2.

Practical Implication. Our analysis demonstrates the ecosystem benefit that wolves can provide through control of red deer numbers, leading to native woodland expansion. Large‐scale expansion of woodlands, facilitated through the return of wolves, can contribute to national climate targets and could provide potential economic benefits to landowners and communities through carbon finance.
Gradient Porous Carbon Superstructures for High‐efficiency Charge Storage Kinetics
Authors: Long Yinying , An Xingye , Yang Yiluo , Yang Jian , Liu Liqin , Tong Xin , Liu Xiongli , Liu Hongbin , Ni Yonghao 
Published: February 2025

AbstractZinc‐ion hybrid supercapacitors (ZHSCs) are emerging for high‐efficiency energy storage. However, single‐layer cathode materials often suffer from low‐charge storage kinetics. Herein, an innovative gradient porous carbon superstructure with enhanced charge storage kinetics is developed, achieved by designing a concentration gradient carbon superstructure to facilitate rapid, directional ion transport and efficient ion storage. The gradient pore design with optimized micropore sizes (0.88 to 0.96 nm) and mesopore size (≈4 nm) enhances the hydrated zinc ion ([Zn(H2O)6]2+) diffusion, facilitating efficient desolvation and Zn2+ ion storage. Furthermore, N/O co‐doping provides pseudo‐capacitance by lowering the energy barrier for C‐O‐Zn bond formation, increasing the defect density and conductivity of the carbon material. Further graphitization improves conductivity and wettability, while a high specific surface area (SSA) offers abundant active sites. ZHSCs fabricated with this gradient porous carbon superstructure exhibit a remarkably high energy density of 101.8 Wh kg−1 at a substantial power density of 503.6 W kg−1, outperforming the reported benchmark materials. The exceptional charge–discharge cycling stability is also demonstrated over 10 000 cycles. This work presents an effective strategy for enhancing charge storage kinetics in supercapacitors.
P3HT‐Based Electroactive Films for In Vitro Neuronal Cell Interfacing
Authors: Campione Paola , Latte Bovio Claudia , Calabrese Giovanna , Santoro Francesca , Messina Grazia Maria Lucia 
Published: February 2025

AbstractNumerous efforts have been made to address the mechanical mismatch between bioelectronic devices and tissues in the past few years. Interfaces that better mimic the properties of biological tissues can be produced with the support of organic materials, which have a unique combination of soft mechanical properties, biocompatibility, and ionic‐electronic conduction, which match the properties of living systems and allow the signal to be transduced at the biotic–abiotic interface. In this context, Poly(3‐hexylthiophene) (P3HT), a p‐type semiconducting polymer, having good biocompatibility, electrical conductivity, and mechanical properties, is studied. In this work, a polymer blend of P3HT and multi‐walled carbon nanotubes (MWCNT) is prepared and deposited on the surface as an electroactive thin film resulting in a tunable nanostructured surface. Further, the biological properties of this new substrate in vitro is evaluated. The conductive polymer‐based substrate and the HT‐22 cell line can be better connected because of this nanostructured surface effect on the cells' responses to local changes in curvature and topography of the materials. This model is simple yet effectively shows the investigation of neuronal responses to morphological characteristics and electronic interfaces.
Universal Measurement Protocol and Cell Designs for Liquid‐Based Active Cooling by the Electrochemical Peltier Effect
Authors: Wakayama Yusuke , Zhou Hongyao , Matoba Fumitoshi , Yamada Teppei 
Published: February 2025

AbstractElectrochemical Peltier (ECP) effect is an emerging cooling technology, capable of active transfer of heat via entropy change of redox reaction. However, the temperature drop (ΔT) producible from the ECP effect is too small for practical use and its limiting factor remains elusive. In this work, a universal measurement protocol using an alternating square‐wave current is proposed, which effectively distinguishes the ECP effect from Joule heating and provides an accurate and reliable assessment of the experimental results. A general expression for the temperature drop at the steady state (ΔTSS) generated from the ECP effect is derived, which is further validated by its agreement with the experimental results. The ΔTSS increases with increasing interelectrode distance, and the largest value of 0.55 K is achieved. The measurement protocol and theoretical model presented in this study have a high level of generality and are universally applicable to other ECP devices.
Harnessing the Ketene Chemistry by Transition‐Metal‐Catalyzed C−H Functionalization
Authors: Feng Zhiming , Xie Yushan , Wu Lili , Wang Chengming 
Published: February 2025

AbstractTransition‐metal‐catalyzed C−H functionalization has become a cornerstone of modern organic synthesis, enabling the efficient formation of various C−C and C‐heteroatom bonds. Ketenes, a class of highly reactive and versatile molecules, have recently been harnessed as powerful substrates for C−H functionalization reactions, unlocking new possibilities for the construction of complex molecular frameworks. This review provides a comprehensive overview of the latest advances in transition‐metal‐catalyzed C−H functionalization with ketenes, encompassing the design of novel catalytic systems, elucidation of reaction mechanisms, and exploration of synthetic applications. By highlighting the current state of the art, challenges, and future prospects, this concept aims to inspire further research and innovation in this rapidly evolving field, ultimately expanding the frontiers of transition‐metal‐catalyzed C−H functionalization with ketenes.