bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of the electrical conductivity of bioactive points on the skin before and after exercise
Authors: Кулбаева М.С. , Жаксыбай Ж.А. , Умбетьярова Л.Б. , Атанбаева Г.К. , Аблайханова Н.Т. , Ыдырыс А. , Тусупбекова Г.А. , Бактыбаева Л.К. , Швецова Е.В. , Аманбай Б.Б. 
Published: August 2021

Физические упражнения - это эффективный профилактический метод защиты от болезней и преждевременного старения. Для нормального функционирования организму нужна физическая нагрузка. Исследование проведено на 17 физиологически здоровых студентах в возрасте от 21 до 25 лет. Анализировали данные по 16 биологически активным точкам по стандартным меридианам, которые связана с активностью соответствующих внутренних органов. Результаты показателей электропроводности (ЭП) биологически активных точек (БАТ) на коже, по стандартным меридианам помогают оценить физиологическое состояние органов при определенной физической нагрузке. Было обнаружено, что значения ЭП БАТ кожи, полученные по стандартным меридианам органов до и после физической активности, увеличивались или уменьшались в некоторых органах. С энергетической точки зрения экономия энергии в организме наблюдается при повышенных и пониженных значениях ЭП БАТ во время физических нагрузок. Было установлено повышенние ЭП (р<0,05) БАТ кожи после физической нагрузки. по стандартным меридианам органов: сердце, тонкий кишечник, толстый кишечник и почки. Было обнаружено, что под влиянием физических нагрузок в биоактивных точках меридианов легких, желудка, мочевого пузыря, печени статистически достоверно снижалось ЭП БАТ (р<0,05).
Exercise is an effective preventive measure against disease and premature aging. For normal functioning, the body needs physical activity. The study was conducted on 17 physiologically healthy students aged 21 to 25 years. Analyzed data on 16 biologically active points along the standard meridians, which are associated with the activity of the corresponding internal organs. The results of indicators of electrical conductivity (ЕС) of biologically active points (BAP) on the skin, according to standard meridians, help to assess the physiological state of organs under a certain physical load. It was found that the blood pressure values EС of cutaneous BAP, obtained from standard organ meridians before and after physical activity, increased or decreased in some organs. From an energy point of view, energy savings in the body are observed with increased and decreased values of EP BAP during physical exertion. An increase in EС (р<0,05) of the BAP skin was found after exercise. along the standard meridians of organs: heart, small intestine, large intestine and kidneys. It was found that under the influence of physical activity in the bioactive points of the meridians of the lungs, stomach, urinary bladder, liver, the EС BAP significantly decreased (р<0,05).
FEATURES OF THE COURSE OF SYSTEMIC LUPUS ERYTHEMATOSUS IN CHILDREN
Authors: Мухаммедова Б.К. , Cepraзueвa C.Ж. , Acкapoвa K.К. , Бериккан А.М. , Эркинова Н.Х. , Аубaкирова A.Д. , Ногаева М.Г. 
Published: August 2021

Проведён обзор клинических исследований особенности течения ювенильной формы системной красной волчанки (СКВ) (до 18 лет), изучены наиболее эффективные и безопасные методы лечения за последние пять лет в базе данных: PubMed, Cochrane Library, Tripdatabase. Нa основании изученных материалов мы выявили, что чаще всего заболеваемость СКВ в детском возрасте приходится на препубертатный период -12,5 лет. Наиболее частой и прогностически тяжелой формой является волчаночный нефрит. В настоящее время в терапии СКВ применяются генно-инженерные биологические препараты (ГИБП), в частности Белибумаб, который является менее токсичным для детского организма и может привести к длительной ремиссии. Таким образом, ранняя диагностика и лечение СКВ может предупредить рецидивы и осложнения заболевания и улучшить прогноз у детей.
This article provides clinical studies of the peculiar features of the systemic lupus erythematosus's course in children under the age of 18, observe the most effective and harmless methods of treating this disease over the past 5 years in the databases: PubMed, Cochrane Library, Tripdatabase. Based on the studied materials, we found that the average age of SLE incidence in childhood is the prepubertal period -12.6 years. The most common and prognostically severe form in children is lupus nephritis. In the treatment of SLE, GIBP has recently been used, particularly of Belimumab, which is less toxic to the child's body and the using of this drug can lead to long-term remission. Thus, based on the obtained data, we can say that it is the earliest diagnosis and treatment of SLE that can prevent the development of severe forms of the disease and improve the prognosis of the incidence of this disease.
ACTUAL PROBLEMS OF OVERCOMING OF PSYCHOLOGICAL BARRIERS ON THE EXAMPLE OF STUDENTS OF MEDICAL EDUCATIONAL INSTITUTIONS
Authors: Тлебалдин Р. , Абиров М. , Желдербаева М.К. , Ергешов Е. , Бисенбаева Ж.Н. 
Published: August 2021

В статье рассмотрены условия преодоления психологических барьеров в обучении студентов медиков. Преодоление психологического барьера это сложный и многогранный процесс, который сопровождается изменениями жизненных условий, статуса вчерашнего школьника, определения своего места в новом коллективе, отношениями с преподавателями, изменениями в организации своего рабочего времени, осознании причастности к будущей профессии врача. Психологический барьер представляет собой определенную внутриличностную преграду, преодоление которой ведет к качественному преобразованию, как деятельности личности, так и самой личности. Кроме этого в статье раскрываются основные причины возникновения психологических барьеров в процессе обучения, где проблема преодоления психологических барьеров учебной деятельности изучалась как в педагогических, так и в психологических исследованиях и оказывает негативное влияние на учебную деятельность студентов.
The article considers the conditions for overcoming psychological barriers in the training of medical students. Overcoming the psychological barrier is a complex and multifaceted process that is accompanied by changes in living conditions, the status of yesterday's student, determining their place in the new team, relationships with teachers, changes in the organization of their working hours, awareness of involvement in the future profession of a doctor. The psychological barrier is a certain intrapersonal barrier, the overcoming of which leads to a qualitative transformation of both the activity of the individual and the personality itself. In addition, the article reveals the main reasons for the emergence of psychological barriers in the learning process, where the problem of overcoming psychological barriers to educational activity has been studied both in pedagogical and psychological studies and has a negative impact on the educational activities of students.
Analysis Of The Effect Of Age On Medication Adherence With Oral Antidiabetes And Oral Antihypertension Drugs Using Pill Count Method
Authors: Mas Ulfa Ninik , Darmawan Rizky 
Published: August 2021

Compliance with taking medication is a problematic patients who get polypharmacy prescribing, this is because of the many drugs that must be consumed. As a result of the consumption of many drugs that cause sufferers of degenerative diseases are not compliant to take medication and health awareness decreases. This is not only experienced in elderly and geriatric patients but in adulthood also experience non-compliance with taking medication due to the many activities, lazy to take medication and also forget. This study was conducted to analyze the effect of age on adherence to taking oral antidiabetic drugs and oral antihypertensive drugs using the pill count method at the Regional Hospital of South Surabaya. The Pill Count method was chosen in this study with the aim of analyzing patient compliance in taking medication by calculating the remaining drug based on the rules of use and dosage when the patient returns to control. In addition, this study also aims to determine the effect of age on patient compliance in taking oral antidiabetic drugs and oral antihypertensive drugs. This research is descriptive observational with prospective data collection. Data analysis used descriptive and continued with statistical analysis using Chi-Square. The results of this study that adherence to take medication for elderly patients who received oral antidiabetic drug therapy obtained as much as 96.7% and 90% in adult patients. Compliance to oral antihypertension drugs in adult patients are 90% and 83.3% in elderly patients. Age does not effect compliance patients with Chi-Square analysis with p value = 0,301 and 0,448 > 0.05.
Physical Evaluation of Anti Acne Mask With Ethanol Extract of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Antin-3 Varieties
Authors: Dipahayu Damaranie , Lestari Kinanti Ayu Puji 
Published: August 2021

Ethanol extract of purple sweet potato (Ipomoea batatas (L.)) leaves of Antin-3 variety contains flavonoids and polyphenols which can be used as a source of acne anti-bacterial because it can inhibit the growth of Staphylococcus aureus. This study aims to obtain data on physical characteristics, acceptability and stability of anti-acne mask formulation of 70% ethanol extract of Antin-3 leaves. The research method used were characteristic, acceptability and stability test. There were 4 types of samples tested, namely base, Antin-3 extract 5%: 10% and 20% (B: F1: F2: F3). The organoleptic results showed that the higher concentration of extract, the darker color of mask and the stronger of extract smell and the softer of consistency. The pH values ​​(B: F1:F2: F3) were respectively 6.46; 5.78; 5.75; 5.46. The value of adhesion (B: F1: F2: F3) were respectively 1.1; 1.46; 2.17 and 4.53 seconds. The value of spreading capacity (B: F1: F2: F3) were respectively 3.89; 4.15; 4.36 and 3.45 cm. The results of the acceptability test showed that F2 was the easiest formula to spread, clean and softest sensation on the skin. The results of the mechanical and cycling test showed that the four samples had not undergo phase separation. Anti-acne mask with 70% ethanol extract of Antin-3 leaves by 10% met the physical characteristics, acceptability and stability.
Optimization of Skin Moisturizer Formula Based on Fixed Oil (VCO, Olive Oil, and Jojoba Oil)
Authors: Rakhma Dita Nurlita , Nailufa Yuyun , Ainun Najih Yuli , Wahjudi Hery 
Published: August 2021

Currently, formulations of skin moisturizers are derived from natural compounds. Fixed oils are known to have compounds that potential to be developed as skin moisturizers based on emollient mechanism. Therefore, this study aims to determine the effect of oil type on the physical characteristics of skin moisturizer creams. In this study, a skin moisturizer cream was formulated using three types of fixed oils: VCO (F1), Olive Oil (F2), and Jojoba Oil (F3). All formulas were tested for physical characteristics of pH, cream type, viscosity, spreadability, and homogeneity. The test results show that all formulas appropriate to the skin pH range, have o/w type creams and homogeneous texture. In the results of the viscosity test, there was a significant difference (p<0.05) with the highest value of viscosity for F2 (16750 ± 250 cP) > F3 (14200 ± 346cP) > F1 (5833 ± 58 cP), while for spreadability test there were also significant differences (p<0.05) with the highest diameter for F1 (5.8 ± 0.1 cm) = F3 (5.7 ± 0.2 cm) > F2 (4.3 ± 0.2 cm). Based on the results, it can be concluded that the type of oil can affect the physical characteristics of the moisturizer formula. F1 and F3 have better physical characteristics than F2.
Pityriasis rosea revealing a viral Hepatitis B
Authors: Karabinta Y , Faye O , Konaté I , Sylla O , Dicko A , Cissé L , Gassama M , Traoré B , Fofana Y , Touré S , Dao S 
Published: August 2021

Pityriasis rosea, described by Gibert in 1860, is a frequent, benign, transient dermatosis, with unknown etiology that affects especially young adults. It is believed to be a consequence of a viral infection, but this argument is not convincing. We report a case of Pityriasis Rosea from Gilbert (PRG) revealing viral hepatitis B. Observation: This was a 47-year-old adult from Diago (commune of Kati), with no known medical and surgical history, who was seen for pink spots scattered throughout the trunk associated with pruritus in which the retained diagnosis was PRG. He have given vaseline with urea 5%, and Mequitazine10mg as treatment. Facing the persistence of this pruritus despite this treatment, a biological investigation was done to look for probable etiology was requested and this led to the diagnosis of an infection with the hepatitis B virus. Conclusion: this observation should lead dermatologists to systematically search for hepatitis B viral infection when facing a PRGs that are very pruriginous and resistant to the usual treatments.Mots clés : Pityriasis rosea, Viral hepatis B
Determinants of abandonment of rabies post-exposure prophylaxis at the Bouaké Anti-rabies Center; Ivory Coast
Authors: Coulibaly M'bégnan , Kouassi Damus Paquin , Yao Gnissan Henri auguste , Kouame Arsène Deby , Konan N'Guessan , Soumahoro Sory Ibrahim , Attoh-Toure Harvey , Tiembre Issaka 
Published: August 2021

In Côte d'Ivoire, a high number of exposed people abandoned the Post-Exposure Prophylaxis. Our objective was to determine the factors influencing the adherence to the Post-Exposure Prophylaxis at the anti-rabies Center of Bouaké. Methods: we carried out an ambispective study, based on the review of patient records from January 2014 to December 2015 and on contacting all patients by phone.Results: A total of 1487 people at risk of rabies infection received Post-Exposure Prophylaxis, whom 54, 4% abandoned their treatment. The majority of the victims was under of 15 years old (56, 8%) and was male (59, 1%). Lesions were predominantly of category III (55, 3%) and 2, 3% was located on the head. In 87% of cases, the biting animal was not properly vaccinated and 66% of the victims consulted within 48 hours after exposure. Among the exposed subjects, 54% had discontinued treatment; the main reasons were cost (76%) and neglect (28%) and it was influenced by household's average income RR=0,741; IC95%= [0,353-0,838].Conclusion: Vaccine prevention, the only effective way to prevent human rabies, faces to high drop-out rate of post-exposure prophylaxis. The main obstacles to the correct observance of this treatment are related on the one hand to the distance of care structures for the rural populations and on the other hand to financial inaccessibility.Keywords : Rabies, Post-exposure prophylaxis, Abandonment, associated factors
Delivery of the antimalaria on advice in pharmacies deprived of the district of Bamako, Mali
Authors: Diallo T , Denou A , Coulibaly BF , Dakouo B , Tangara D , Coumare K , Coulibaly B , Loup-Rey J 
Published: August 2021

Context and Objective: Malaria is a well-known disease of the Malian population; as a result pharmacists are giving more and more advices regarding this disease to the population. In order to better understand the problem of the delivery of antimalarials without prescription, we initiated this study with the objective of studying the practice of dispensing antimalarials without prescription in accordance with the guidelines of Mali's national malaria program.Patient and Methods: This was a cross-sectional descriptive study on the delivery of antimalarials based on counseling. We included in the study all clients aged 15 years and over who were received in Bamako pharmacies for a non-prescription antimalarial medication for themselves or for another person based on mutual consentment.Results: The study was carried out in 199 of the 230 pharmacies in the district of Bamako; we recorded 466 requests for advice. The sex ratio M / F was 1.7 and 28.9% of clients for whom the drug was intended were under 20 years of age, in which case 52.4% of the costumers were not the actual patients. Artemisinin-based combination therapy was the most recommended (52%). Sulfadoxine Pyrimethamine was the most widely purchased antimalarial among non-CTA antimalarials. In 34.5% of cases, antimalarials are associated with other therapeutic classes where analgesics / antipyretics constitute 77.6% of these classes followed by antibiotics (21%).Conclusion: The pharmacy is the first resort in the healthcare system for the majority of clients with clinical suspicion of malaria.Keywords: Advice, malaria, pharmacy, Bamako
The Role of Alcohol Consumption and Smoking Habits in Increasing the Diabetes Mellitus Risk in Adult Men and Women with Central Obesity in Indonesia
Authors: Setyaji Diyan Yunanto , Purnawijayanti Hiasinta Anatasia 
Published: August 2021

Central obesity is more predictive of measuring the risk of type 2 diabetes compared to anthropometric indicators of general obesity. The results of previous studies are still inconsistent and the causal relationship that had not been well explained between the determinant factors and the increasing incidence of diabetes mellitus. This study aims to determine the relationship between alcohol consumption and smoking habits in increasing the risk of diabetes mellitus in adult males and females who are central obesity in Indonesia. The analysis presented in this study was based on the data from a population-based, cross-sectional, nationally representative survey (Indonesian Basic Health Research 2018/RISKESDAS 2018). In total, 12726 men and 18637 women aged 18–65 years were enrolled. A validated questionnaire, smoking card, and alcohol card were used for the assessments. There was a significant difference (p <0.000) in the proportion of diabetes mellitus incidence between men and women in both age groups who consumed less than 1 pack of cigarettes or more than 1 pack per day. The age difference for the sexes did not show a statistically significant association with alcohol consumption of either under 5 servings or above 5 servings per day for the incidence of diabetes mellitus. Women with central obesity had an adjusted prevalence ratio of 1.7 times higher for diabetes mellitus than men. There were negative multiplicative interactions between sexes and smoking status (interaction PR = 0.685; 95% CI = 0.52-0.88) and cigarette exposure (0.65; 0.52-0.80) in women. The effects of alcohol consumption and their interactions with sex did not have a significant relationship. There is an increased risk of diabetes mellitus especially in women with central obesity. Alcohol consumption by people with central obesity has an interaction with gender in an increased risk of diabetes mellitus which is higher in women than men.
Toen en nu: heeft het gevangeniswezen de middelen om zijn doelen te bereiken?
Authors: Molleman Toon 
Published: August 2021

Then and now: Does the Dutch prison system have the means to achieve its goals?
Starting point in this article is the classical work of Herman Franke on the history of the Dutch prison system. Franke showed how policymakers and other people who influence prison policy and practice tried to reduce criminal behavior in the past two centuries. These attempts had various backgrounds, among which religious, sociological and biological, and varied greatly in scientifical substantiation. Every new prison policy elicited high hopes, but in practice criminal behavior was rarely pushed in the desired direction. The means of the prison system, among which staff, buildings and regime regulations, showed to be much later realized than the formulated goals established by law. Another problem that came up more than once in history was that the urge and compulsion mechanism of a new prison policy lacked support base and (agogical) skills among prison staff. Recommendations are formulated for the (near) future in favor of more successfull prison policy implementations.
Cephalopod species identification using integrated analysis of machine learning and deep learning approaches
Authors: Tan Hui Yuan , Goh Zhi Yun , Loh Kar-Hoe , Then Amy Yee-Hui , Omar Hasmahzaiti , Chang Siow-Wee 
Published: August 2021

BackgroundDespite the high commercial fisheries value and ecological importance as prey item for higher marine predators, very limited taxonomic work has been done on cephalopods in Malaysia. Due to the soft-bodied nature of cephalopods, the identification of cephalopod species based on the beak hard parts can be more reliable and useful than conventional body morphology. Since the traditional method for species classification was time-consuming, this study aimed to develop an automated identification model that can identify cephalopod species based on beak images.MethodsA total of 174 samples of seven cephalopod species were collected from the west coast of Peninsular Malaysia. Both upper and lower beaks were extracted from the samples and the left lateral views of upper and lower beak images were acquired. Three types of traditional morphometric features were extracted namely grey histogram of oriented gradient (HOG), colour HOG, and morphological shape descriptor (MSD). In addition, deep features were extracted by using three pre-trained convolutional neural networks (CNN) models which are VGG19, InceptionV3, and Resnet50. Eight machine learning approaches were used in the classification step and compared for model performance.ResultsThe results showed that the Artificial Neural Network (ANN) model achieved the best testing accuracy of 91.14%, using the deep features extracted from the VGG19 model from lower beak images. The results indicated that the deep features were more accurate than the traditional features in highlighting morphometric differences from the beak images of cephalopod species. In addition, the use of lower beaks of cephalopod species provided better results compared to the upper beaks, suggesting that the lower beaks possess more significant morphological differences between the studied cephalopod species. Future works should include more cephalopod species and sample size to enhance the identification accuracy and comprehensiveness of the developed model.