bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Mitochondrial Brown Adipose Tissue Maintenance Factor Nipsnap1 Interfaces Directly with the Beta-Oxidation Protein Machinery
Authors: Tsai Pei-Yin , Qu Yue , Walter Claire , Liu Yang , Cheng Chloe , Barrow Joeva J 
Published: December 2024

ABSTRACTBackgroundThe activation of brown adipose tissue (BAT) is associated with improved metabolic health in humans. We previously identified the mitochondrial protein 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like 1 (Nipsnap1) as a novel regulatory factor that integrates with lipid metabolism and is critical to sustain the long-term activation of BAT, but the precise mechanism and function of Nipsnap1 is unknown.ObjectivesDefine how the regulatory factor Nipsnap1 integrates with lipid metabolism.MethodsWe generated adeno-associated viral (AAV) constructs that overexpress Nipsnap1 in the thermogenic fat of mice. We then measured both whole-body and cellular mitochondrial metabolism and mapped the first Nipsnap1 interacting protein-protein network.ResultsHerein, we show that adipose-specific overexpression of Nipsnap1 in mice increases energy expenditure through the utilization of lipids as an energy substrate. The increase in energy expenditure results in reduced weight gain. Additionally, we show that Nipsnap1 overexpression in primary adipocytes increases lipid beta-oxidation. Moreover, we mapped the first protein- protein network of Nipsnap1 in brown adipocytes and show that Nipsnap1 interacts with proteins that regulate both peroxisomal and mitochondrial fatty acid beta-oxidation.ConclusionThis study elucidates a mechanistic function of Nipsnap1 in thermogenic fat where Nipsnap1 facilitates a functional connection between peroxisomal and mitochondrial beta-oxidation pathways. By enhancing lipid utilization as energy substrates, Nipsnap1 plays a pivotal role in sustaining thermogenic fat activation to increase energy expenditure. These findings underscore the potential of Nipsnap1 as a therapeutic target for metabolic health.
Analyzing shifts in structural dependence between oil prices and exchange rates in oil-importing economies
Authors: Yamaka Woraphon 
Published: December 2024

PurposeThe primary purpose of this study is to unveil the relationship between oil prices and exchange rates, with a specific focus on five major oil-importing countries. By examining this relationship, the research aims to provide valuable insights for policymakers, investors and stakeholders operating in the global economic landscape.Design/methodology/approachThe study employs a methodological approach to ensure robust and reliable findings. First, we assess the stationarity of the time series data to establish a solid analytical foundation. Subsequently, we construct GARCH(1,1) models to capture the persistence of the volatilities inherent in the data. Building upon this, we propose the novel application of the Markov-switching R-vine copula approach, which enables us to capture structural changes and measure the dependencies between oil prices and exchange rates.FindingsOur findings uncover significant negative relationships between oil prices and exchange rates across the examined economies while revealing varying degrees of interdependency among these variables. Notably, we elucidate distinct tail dependence structures, encompassing both symmetric and asymmetric aspects, which hold profound implications for risk assessment and portfolio management strategies. Furthermore, this study confirms the presence of regime-switching dynamics, elucidating how the co-movement patterns between oil prices and exchange rates evolve across different states or regimes, reflecting the dynamic nature of these interconnected markets.Originality/valueThe originality and value of this study lie in its comprehensive approach to understanding the relationship between oil prices and exchange rates. By accounting for structural changes and regime-switching behaviors, the research provides a nuanced understanding of the complex dynamics at play. The novel application of the Markov-switching R-vine copula approach contributes to the methodological advancement in this field of study. Furthermore, the insights derived from this research offer practical implications for policymakers, investors and stakeholders navigating the complexities of the global economic landscape, enabling them to make informed decisions and develop effective strategies to mitigate risks and capitalize on opportunities.
Exploring the mechanisms of different social norms influencing green consumption attitude and behavior
Authors: Hu Xiaojuan , Hu Jingchao 
Published: December 2024

PurposeGreen consumption is conducive to global sustainable development. This study aims to explore how social norms (i.e. descriptive norms and injunctive norms) impact green consumption attitude and behavior. It examines the mediating role of impression management and the moderating role of self-construal.Design/methodology/approachWe conduct two online experiments to collect data. A total of 1,070 Chinese consumers participate in Study 1. Study 2 involves 541 Chinese consumers.FindingsThe results show that descriptive norms and injunctive norms stimulate consumers’ impression management, which then promotes green consumption attitude and behavior. When an individual is more predisposed to interdependent self-construal, descriptive norms are more effective in activating impression management and then affecting green consumption attitude and behavior.Originality/valueSocial norms are an effective intervention measure for green consumption. Its influence process is complex. However, previous studies mainly identified the mediating role of personal norms. Other mediating mechanisms and boundary conditions are still unclear. This study identifies the mediating role of impression management and the moderating role of self-construal. It sheds new light on how social norms impact green consumption.
Does a self-managed organization leave employees behind? A critical review of the current trend
Authors: Butsch Thomas , Bell Robin 
Published: December 2024

Purpose
Organizations need to achieve some level of self-management and delegation to run effectively without constant management oversight, which has led to numerous organizational frameworks and models being developed, including TEAL, Holacracy, the Spaghetti Organization and the Liberated Firm. As a result, we should consider whether employees desire this, and whether it is a “new future” or just a passing fad or trend. Another question arising from employee encounters is, do we leave some employees behind as they are not confident, or feel inadequate for the new organizational structures, as they require more direction? This paper reviews the literature to explore and answer these questions.

Design/methodology/approach
This paper reviews the literature on self-management frameworks and models in respect to their potential application and in light of the implication for employees.

Findings
Being self-managed throughout all organisations, as most champions of self-managed frameworks may argue, cannot be the solution if it is only appropriate for a subset of workers. We propose a gradual approach: we should implement self-management where it is acceptable, and employees are interested and capable of engaging in the transition to new management frameworks. However, we recommend against attempting self-management in situations where it is inappropriate.

Research limitations/implications
The paper is based on a review of existing literature with findings derived from general trends and workforce characteristics, but do not account for specific industries, organizational types or roles. As a result, the conclusions may not be applicable to all organizational contexts or to certain specialized employee groups. Given the restricted breadth of research into SMOs, future research could explore the applicability and success of SMOs in specific contexts.

Practical implications
Organizations are encouraged to take an incremental approach to implementing self-management frameworks. Instead of enforcing self-management universally, it should only be introduced in areas where employees are willing, capable and equipped to handle the transition. Further employers must recognize that self-management is not suitable for all employees. Organizations should assess employee readiness and provide adequate support or alternative structures where needed.

Originality/value
While the transition to self-managed organisations is widely discussed in the literature, as evidenced by the proliferation of organisational models and frameworks, there has been little discussion of the potential for different organisations to apply such frameworks and models in practice, as well as the implications for employees. Given that the business world is not homogeneous, it is reasonable to assume that not all people are suitable for working without a boss, and this must be considered.
Integrating exoskeletons in the construction sector: a systematic review of empirical evaluation tools and future directions
Authors: Al-Khiami Mohamad Iyad , Lindhard Søren Munch , Wandahl Søren 
Published: December 2024

PurposeThis study aims to evaluate and synthesize literature on exoskeleton implementation in the construction industry to understand their current applications, evaluate existing research approaches and identify critical areas for future investigation. Through a comprehensive analysis of empirical studies, the research seeks to establish a clear roadmap for advancing exoskeleton adoption in construction work.Design/methodology/approachThis study conducts a systematic literature review following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. By searching relevant databases and applying predefined inclusion criteria, the review focused on empirical studies that evaluate the effectiveness and acceptance of exoskeletons in construction. Both objective parameters (EMG data, Kinematic analysis, heart rate) and subjective parameters (user comfort, perceived exertion, usability surveys) were analyzed to assess how impactful are exoskeletons among construction workers.FindingsThe review identified 236 publications, of which 36 were included, revealing several critical insights: (1) A significant reliance on studies conducted in controlled environments, accounting for 77.78% of studies. (2) A limited representation of actual construction workers, mainly non-construction worker volunteers, which may affect the practical relevance of the findings. (3) A significant gap exists in standardized evaluation protocols, with researchers using varying assessment methods that hinder cross-study comparisons. (4) Predominantly short-term nature of existing studies. These findings highlight the need for more real-world testing, standardized evaluation frameworks and longitudinal studies.Originality/valueThis review contributes original insights into the deployment of exoskeletons in the construction sector, particularly highlighting the industry's gap in direct, in situ engagement with construction workers. It suggests that future research should prioritize long-term, onsite studies to achieve a more comprehensive understanding of exoskeletons’ impacts, thus supporting the development of targeted intervention strategies for reducing work-related musculoskeletal disorders (WMSDs) among construction workers.
Cultural heritage experiences in the metaverse: analyzing perceived value and behavioral intentions
Authors: Sepe Fabiana , Luongo Simone , Di Gioia Leonardo , Della Corte Valentina 
Published: December 2024

PurposeThis study aims to investigate the impact of digital technologies on enhancing visitor engagement and behavioral intentions in cultural heritage settings within the metaverse.Design/methodology/approachThe work proposes an extended version of the theory of planned behavior (TPB) to investigate the factors influencing individuals’ intention to engage in metaverse experiences in cultural heritage sites. To this aim, the research employs a quantitative approach, utilizing a questionnaire to collect data from participants. We selected 280 valid responses from cultural tourists. Then, the structural equation model (SEM) was developed to analyze the relationships between TPB and novel constructs, namely utilitarian value, hedonic value and social value and the endogenous latent variable of intention.FindingsThe results emphasize that individuals’ intention to participate in metaverse experiences within cultural heritage sites relies on a multifaceted process. All the relationships are supported, except the influence of perceived behavioral control on intention to engage in metaverse cultural experiences.Originality/valueThe originality of the research lies in its exploration of the influence of perceived hedonic, social and utilitarian values on visitors’ behavioral intentions within the context of metaverse museums.
Condition of local public buildings and the quality of local welfare services
Authors: Hopland Arnt O. , Kvamsdal Sturla 
Published: December 2024

Purpose
The purpose of this study is to analyze how public buildings and their condition relate to how satisfied users are with related public services.

Design/methodology/approach
Data from two surveys are coupled: a survey of public officials on the state of public buildings and on their expectation of the impact on public services and a citizen survey that includes satisfaction measures for public services. Public records on finances and other relevant aspects of local governments are also considered.

Findings
Expectations of public officials on the impact of building conditions on services are weakly correlated with satisfaction of the public with public services. When factors that may impact building conditions as well as services are controlled for, the results are fragmented. For nursing homes, poor building conditions and low satisfaction with elderly care are significantly related. For kindergartens and schools, as well as the overall measure, there is no significant relationship between building conditions and satisfaction with public services.

Originality/value
The results are contrary to earlier analysis and may indicate data quality issues. The results also demonstrate the lack of understanding of how public buildings support and facilitate the production of public services.
Green human resource management and sustainable performance: serial mediating role of green knowledge management and green innovation
Authors: Riaz Adil , Al-Okaily Manaf , Sohail Amir , Ashfaq Khurram , Rehman Shafique Ur 
Published: December 2024

Purpose
The sustainable performance of manufacturing companies may commence with employees’ eco-friendly initiatives. The management is responsible for employee green initiatives, requiring the human resource department to develop and implement green strategies. Therefore, it is essential to investigate how green human resource management enhances sustainable performance among manufacturing personnel. This study aims to determine if the green knowledge management and green innovation of manufacturing employees serve as serial mediators in the relationship between green human resource management and sustainable performance. Additionally, if artificial intelligence facilitated the relationship between green human resource management, green knowledge management and sustainable performance.

Design/methodology/approach
The data were gathered from manufacturing firm managers and analyzed using partial least squares structural equation modeling.

Findings
The results indicated a notable and positive correlation between green human resource management and sustainable performance, green knowledge management and green innovation. Green knowledge management and green innovation exhibited significant positive correlations with sustainable performance. Additionally, green knowledge management and green innovation facilitated the connection between green human resource management and sustainable performance. This relationship was serially mediated by green knowledge management and green innovation. Furthermore, artificial intelligence moderated the relationship between green human resource management, green knowledge management and sustainable performance.

Practical implications
This study suggests that management can use study findings in decision-making to improve firms’ sustainable performance.

Originality/value
This study provides novel empirical evidence by investigating the mediation roles of green knowledge management and green innovation between green human resource management and sustainable performance through the lens of the natural resource orchestration theory.
Lesson study and the challenges of initial teacher education in Europe: keys to sustainability. A literature review
Authors: Rodríguez-Robles Cristina , del Pino Rodriguez Lorena , Peña Trapero Noemí , Serván-Núñez María J. , Soto Gómez Encarna 
Published: December 2024

PurposeTo present a review of the current state of lesson study (LS) in initial teacher education (ITE) in Europe.Design/methodology/approachA systematic search, combined with heuristic and hermeneutic analysis, was conducted in both English and Spanish using indexed academic databases to collect research and experiences of LS in ITE across Europe. The core areas or analysis categories included sustainability, observation and tutoring, the connection between schools and universities, the value of pedagogical knowledge and LS models.FindingsLS in ITE has seen significant growth in Europe since 2015, particularly in universities where it has established a strong presence. The variety of proposals reflects how institutions have adopted and expanded LS models, indicating a stronger connection between universities and schools. The sustainability of LS hinges on the efforts of a core teaching and research group that not only transforms teaching but also explores learning processes in LS. There is growing interest in improving observation strategies and incorporating pedagogical knowledge in LS, although more in-depth analyses of the learning and teaching processes from both perspectives are still needed.Research limitations/implicationsSearching for references in English and Spanish may limit the visibility of relevant research conducted in other languages and regions, potentially excluding important experiences from non-English or non-Spanish-speaking countries.Originality/valueThis work is the first review of literature on LS in ITE focused on Europe, engaging with and building upon the latest global reviews in ITE and LS while introducing new areas of contrast.
The Well-Being of Future Generations Act (Wales, 2015): towards an ecosystem perspective
Authors: Cummings Beth , Burvill Samantha , Bowen Robert 
Published: December 2024

Purpose Recent times have seen an increasing emphasis on sustainable development as a means of enacting positive regional change. There has also been an emergence in discussions around well-being and its role in promoting holistic sustainable development, such as in Wales through the Well-Being of Future Generations Act (Wales). This paper aims to investigate the role that the Well-Being of Future Generations Act (Wales) currently plays in the ecosystem across South West Wales and ways in which the Well-Being Act could be developed and implemented further.Design/methodology/approach This qualitative research is based on seven semi-structured interviews conducted with participants drawn from a range of entrepreneurial ecosystem actors in South West Wales, UK. Interview data were analysed using thematic analysis, leading to the establishment of seven themes.Findings The findings suggest that there is passion and positivity around the Well-Being of Future Generations Act amongst ecosystem actors. However, policymakers need to consider how to extend the reach of the principles of the Well-Being of Future Generations Act beyond public bodies. This could be achieved through more effective communication of the values of the act and increased collaboration between various stakeholders.Originality/value The concept of well-being remains relatively new in the context of regional economic development and therefore requires closer investigation, particularly how this can be evaluated. Wales is one of three countries worldwide to implement well-being legislation, and there is a lack of research examining the implementation of the Well-Being Act, particularly from regional development and an entrepreneurial ecosystem perspective.
Development of a conceptual framework for entrepreneurial culture
Authors: Ludwig David , van Laak Jona 
Published: December 2024

PurposeInnovation is key. It improves a nations’ standing in international competition and in-creases the productivity of the workforce – a significant aspect in aging societies with a declining entrepreneurial activity. But how can innovation be fostered? This paper argues that entrepreneurial culture is an underestimated solution to this difficult challenge. It therefore differs from common models in which other measures such as financial capital or networks play a predominant role and thus mask the influence of entrepreneurial culture on innovation in entrepreneurial ecosystems.Design/methodology/approachUsing a qualitative literature analysis, the paper links various interdisciplinary touch points to the entrepreneurial ecosystem – including the individual-focused cognitive aspects of entrepreneurs, the social and spatial communities and the ecosystem as a service model.FindingsThe framework is conceptualized as a multi-layer model, enabling a discussion of policy measures in socioeconomic spaces with a short- and long-term perspective. It dispenses artificial assumptions and considers the complexity of human behavior as a strong and reciprocal driver of entrepreneurial culture.Practical implicationsWith this framework, the paper tends to qualify policy makers and researchers in a de-tailed manner, when it comes to the formulation and application of culture-focused innovation policies.Originality/valueThe paper enriches the existing research with a new perspective on the relation between entrepreneurial culture and entrepreneurial ecosystems, which especially emphasizes the entrepreneurs experienced reality and its multi-level embeddedness.
Optimizing health organization performance and patient care outcomes via predictive analytics: implications for data science and artificial intelligence research
Authors: Wan Thomas T.H. , Wan George J. 
Published: December 2024

PurposeThis commentary presents the analytic development of patient classification, health resource use and outcome research and identifies opportunities to perform longitudinal research.Design/methodology/approachThe authors use a transdisciplinary framework to formulate multilevel models for ascertaining the causal relationship between hospital efficiency and effectiveness in panel data analysis.FindingsThe longitudinal design of organization research enables to delineate the relationship between hospital performance and quality of care in future research.Research limitations/implicationsThe inclusion of multivariates in health organization research and modeling is pivotal to the identification of a comprehensive set of predictor variables. The authors signify the need to build a systems-oriented theoretical framework to integrate micro- and macro-level predictor variables in conducting data analysis.Practical implicationsThe authors signify the need to build a theoretical framework to integrate micro- and macro-level predictor variables in conducting data analysis.Social implicationsHealth organization research is essential to broaden the scope of health services research and policy development, particularly related to global health as noted in the promotion of sustainable development and health goals.Originality/valueHealth organization research should include a complex set of exogenous and endogenous variables in designing and modeling the determinants of hospital performance and patient care outcomes.