bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studi Kasus: Penerapan Padma Sebagai Terapi Untuk Menstimulasi Tumbuh Kembang Anak Down Sindrom
Authors: Harini Rika 
Published: November 2021

Abstrak Kejadian down sindrom selama 17 tahun terakhir meningkat cukup pesat dengan perbandingan 1:700 kelahiran hidup. Jumlah anak penderita down sindrom di dunia mencapai 8 juta kasus dan di Indonesia diperkirakan lebih dari 3 tiga ribu kasus. Anak down sindrom memiliki masalah dalam tumbuh kembangnya yang berbeda dan terlambat dibandingkan dengan anak normal, sehingga memerlukan terapi khusus salah satunya adalah Padma. Padma adalah Pijat Anak Down sindrom Mastakaraga Shobia, merupakan jenis terapi pijat yang memberikanstimulasi pada jalur-jalur sensori sumsum tulang dan kepala secara lembut melalui jalur persyarafan dan pembuluh darah melalui sub terminal tubuh dengan tujuan tercapainya kelancaran dan keseimbangan proses dalam tubuh. Karya ilmiah ini menggunakan metode survey deskriptif dengan pendekatan studi kasus. Didapatkan hasil positif terhadap perkembangan anak down sindrom setelah diberikan terapi Padma. Keseimpulan: terapi Padma sangat efektif dalam menstimulasi tumbuh kembang anak down sindrom. Saran: Terapi Padma dapat menjadi salah satu terapi komplementer untuk menstimulasi tumbuh kembang anak down sindrom.Kata Kunci: Pijat; Down Sindrom; PadmaAbstract The incidence of down syndrome during the last 17 years has increased quite rapidly with a ratio of 1:700 live births. The number of children with Down syndrome in the world reaches 8 million cases and in Indonesia it is estimated that more than 3 three thousand cases. Children with Down syndrome have problems in growth and development that are different and late compared to normal children, so that requires special therapy, one of which is Padma. Padma is a Child Down Massage of Mastakaraga Shobia syndrome, a type of massage therapy that provides stimulation of the sensory pathways of the bone marrow and head gently through nerve supply and blood vessels through the sub-terminal of the body with the aim of achieving smooth and balance processes in the body. This scientific work uses descriptive survey method with a case study approach. Positive results were obtained for the development of Down syndrome children after being given Padma therapy. Conclusion: Padma therapy is very effective in stimulating the growth and development of children with Down syndrome. Suggestion: Padma therapy can be one of the complementary therapies to stimulate the growth and development of children with Down syndrome.Key words: Massage; Down Syndrome; Padma
Pemanfaatan Media Video dan Market Plan dalam Mata Pelajaran IPA Pokok Bahasan Sistem Pencernaan Manusia untuk Meningkatkan Hasil Belajar
Authors: Hindasah Ida 
Published: November 2021

AbstractBased on the results of observations made at Karangmulya I Public Elementary School and the author's experience that the material in the human digestive system of teachers is often difficult when teaching so that learning outcomes obtained by students are less satisfying. This study aims to (1) Develop learning by utilizing video media and market plan methods, (2) find out the development steps in learning, and (3) find out how far the merging of video media and market plan methods can improve student learning outcomes in Natural Sciences class VI subject of the human digestive system. The results of this study indicate that the learning media by utilizing video collaborated with the market plan method in science subjects the subject of the human digestive system shows an increase. This is evidenced by the acquisition of student values above the KKM. This learning work has been disseminated to colleagues especially in SDN Karngmulya I. Keywords: Class VI Science;Human Digestion;Video Media and Market Plan AbstrakBerdasarkan hasil observasi yang dilakukan di SDN Karangmulya I dan pengalaman penulis bahwa dalam materi sistem pencernaan manusia guru seringkali Kesulitan saat mengajarkanya sehingga hasil belajar yang diperoleh peserta didik kurang memuaskan. Penelitian ini bertujuan untuk (1) Mengembangkan pembelajaran dengan memanfaatkan media video dan metode market plan, (2) mengetahui langkah-langkah pengembangan dalam pembelajaran, dan (3) mengetahui sejauh mana penggabungan media video dan metode market plan dapat meningkatkan hasil belajar peserta didik pada mata pelajaran IPA kelas VI pokok bahasan sistem percernaan manusia. Hasil penelitian ini menunjukkan bahwa media pembelajaran dengan memanfaatkan video yang dikolaborasikan dengan metode market plan dalam mata pelajaran IPA pokok bahasan sistem pencernaan manusia menunjukan adanya peningkatan. Hal ini dibuktikan dengan perolehan nilai peserta didik di atas KKM. Karya pembelajaran ini telah didesiminasikan kepada rekan sejawat khususnya di lingkungan SDN Karangmulya I. Kata kunci: IPA Kelas VI; Media Video dan Market Plan;Pencernaan Manusia.
Pembelajaran online dengan Aplikasi Zoom Meeting di Kelas 5 SDN 1 Selaawi di Masa Pandemi Covid-19
Authors: Solihin Ahmad 
Published: November 2021

Tahun 2020 merupakan tahun diman penyebaran Covid-19 yang semakin tidak terkendali hampir di seluruh Negara di dunia dan tidak terkecuali negara kita Indonesia marasakan dampaknya. kebekuan terjadi pada berbagai sektor tak terkecuali sektor pendidikan yang sama sekali tidak bisa melaksanakan tatap muka pembelajaran, menanggapi keadaan ini pemerintah mengeluarkan kebijakan seluruh sekolah tidak boleh melaksanakan pembelajaran di kelas dan bertatap muka secara langsung. Kebijakan Pembelajaran Jarak Jauh (PJJ) dengan program bantuan kuota belajar yang dikeluarkan pemerintah sebagai solusi agar sector pendidikan tetap berjalan kreatifitas guru dituntut untuk bisa menggunakan berbagai flatporm aplikasi pembelajaran online yang tersedia sangat banyak namun kemanfaatan dan efektifitasnya sangat berbeda. Salah satu upaya untuk menyikapi kebijakan pemerentah, kelas 5 SDN 1 Selaawi Garut mengambil langkah pembelajaran dengan memanfaatkan fasilitas Aplikasi Zoom Meeting yang bisa diakses melalui kuota belajar sebagai alternatif strategis yang sangat efektif bagi keberlangsungan proses belajar di tengah pandemi. Dengan metode pengkajian kualitatif dapat dijadikan rujukan untuk mengetahui proses pembelajaran guru dan respon siswa di kelas 5 SDN 1 Selaawi dalam pembelajaran online yang baik dengan aplikasi Zoom Meeting
Manajemen Pendidikan Karakter Berbasis Al-Qur’an, Al-Hadits dan Ijtihad
Authors: Abidin Zaenal 
Published: November 2021

AbstractManajemen adalah suatu upaya atau usaha dalam mengelola sebuah organisasi atau lembaga secara efektif, efisien, dan profesional. Sedangkan manajemen pendidikan karakter adalah sebuah proses yang dilakukan secara bersama, melibatkan banyak orang , dan lembaga dalam rangka mewujudkan cita-cita tujuan pendidikan nasional, agar peserta didik menjadi manusia yang beriman, bertakwa kepada Tuhan Yang Maha Esa, dan berakhlak mulia. Pendidikan karakter bukan hanya mengajarkan kecerdasan intelektual semata kepada peserta didik ( murid ), akan tetapi juga pendidikan karakter menanamkan kesadaran akan pentingnya nilai-nilai moral, sopan santun, budi pekerti, toleran, moderat, rendah hati, dan berakhlak mulia. Di sisi lain, jauh sebelum manusia mengenal istilah pendidikan karakter, Al-Qur’an telah mengajarkan kepada umat manusia akan pentingnya pendidikan karakter,yaitu : agar manusia pandai bersyukur, atas segala nikmat pemberian Tuhan, berbuat baik kepada kedua ibu dan bapak, serta peduli terhadap sesama. Al-Qur’an juga membimbing manusia agar menjadi pribadi-pribadi yang unggul. Yaitu pribadi yang gemar membaca, yang mengenal jati dirinya,mengenal Tuhannya,suka menulis, dan penelitian menjadi kebutuhan hidupnya. Bahkan hadits Nabi dengan jelas dan tegas menjelaskan, bahwa manusia sejak lahir sudah membawa potensi pendidikan karakter, yakni : memiliki hati nurani yang baik dan pemikiran yang baik pula,sehingga dapat mengembangkan potensi dirinya sesuai dengan tuntutan dan perkembangan zamanKata Kunci: Manajemen, Pendidikan, Al-Qur’an, Al-Hadits, Ijtihad AbstractManagement is an effort or effort in managing an organization or institution effectively, efficiently and professionally. Meanwhile, character education management is a process that is carried out jointly, involving many people and institutions in order to realize the ideals of national education goals, so that students become human beings who believe, fear God Almighty, and have noble morals. Character education not only teaches intellectual intelligence only to students, but also character education instills awareness of the importance of moral values, courtesy, character, tolerance, moderation, humility, and noble character. On the other hand, long before humans recognized the term character education, the Al-Qur'an has taught mankind the importance of character education. Namely: so that humans can be smart to be grateful, for all the blessings given by God, to do good to both mothers and fathers, and to care for others. Al-Qur'an also guides people to become superior individuals. Namely, a person who likes reading, who knows his identity, knows his God, likes to write, and research is his life necessity. Even the hadith of the Prophet clearly and emphatically explains, that since birth humans have brought the potential for character education, namely: having a good conscience and good thinking, so that they can develop their potential in accordance with the demands and developments of the times
Long-term oncological and functional results of robot-assisted radical prostatectomy
Authors: Ramazanov K. K. , Kolontarev K. B. , Gens G. P. , Govorov A. V. , Vasilyev A. O. , Sadcheko А. V. , Alaverdyan A. I. , Stroganov R. V. , Skrupskiy K. S. , Kim Yu. A. , Shiryaev A. А. , Pushkar D. Yu. 
Published: November 2021

Prostate cancer (РСа), being one of the leading causes of cancer mortality in men in Russia and in a number of other countries of the world, remains an urgent problem for modern oncourology, and the choice of surgical method is an important task for a surgeon. Such a pronounced interest in robot-assisted radical prostatectomy (RARP) in patients is driven by good tolerance and effectiveness of these surgical interventions, despite the fact that radical prostatectomy is considered to be the "gold standard" for treatment of patients with clinically localized РСа with regard to European Association of Urology data. The long-term oncological and functional results and the quality of life of patients after RARP deserve close attention and thorough study. According to the data presented in this article, it is obvious that RARP is the preferred method for surgical treatment of РСа, since oncological and functional results in the long-term follow-up are comparable to the results after radical prostatectomy, and according to some authors, these results are superior to the results of radical prostatectomy. The results of the study will allow to continue further introduction of RARP into clinical practice and its popularization as a method of surgical treatment of patients with localized PCa, which will reduce the length of hospital stay of patients, accelerate their medical and social rehabilitation, and improve the quality of medical care.The amount of data on the study of distant oncological and functional results of RARP as well as its superiority over other treatment methods is limited in medical literature, which prompted us to conduct our own research. Currently the urological clinic of the A.I. Evdokimov Moscow State University of Medicine and Dentistry continues work aimed at studying the longterm results of RARP in the first patients in Russia.
First experience of superselective embolization of renal arteries supplying the tumor with subsequent laparoscopic kidney resection
Authors: Astashov V. L. , Shapovalov V. V. , Balanyuk V. V. , Zagorul’ho A. I. , Kozlov D. V. , Andreeva M. A. , Sinitsyna O. R. , Radomskiy A. S. 
Published: November 2021

Background. Patients with signs of tumor lesions in a single kidney or in the only one functioning kidney, with bilateral renal tumors are at high risk of functional failure or insufficiency of the kidney after surgery. Joint discussions with specialists in X-ray endovascular surgeries resulted in the development of a treatment algorithm for patients with localized kidney cancer who require organ-sparing surgery without ischemic kidney resection.Objective: to evaluation of the immediate results of two-stage surgical treatment of localized kidney cancer in patients with signs of tumor lesions in a single kidney or in the only one functioning kidney, with bilateral renal tumors, including superselective embolization of the artery supplying the tumor at the first stage, and laparoscopic kidney resection without renal ischemia parenchyma at the second stage.Materials and methods. This study included 5 patients with localized kidney cancer, who underwent two-stage treatment at Moscow Regional Oncology Dispensary between 24.03.2021 and 19.04.2021. The first stage included superselective embolization of the artery supplying the tumor; the second stage implied laparoscopic kidney resection 6-7 days following the first stage.Results. The median age of the patients was 62 years (range: 42-73 years). Four patients (80%) had unilateral kidney lesions, while 1 patient (20 %) had bilateral (synchronous) kidney cancer. The mean RENAL score was 8 (range: 6-10); patients were distributed as follows: score 4-6 in 40 %, score 7-9 in 40 %, and score >10 in 20 % of patients. At the first stage, patients underwent endovascular embolization of the branches of the renal artery. Patients had superselective embolization of either middle (n = 3; 60 %), upper (n = 1; 20 %), or lower (n = 1; 20 %) segmental arteries supplying the tumor. In one of them (20 %), we identified 3 large arterial branches; in another one (20 %), we identified 2 large arterial branches.At the second stage, we performed laparoscopic kidney resection. None of the patients required renal artery clamping, because there was an excellent visualization of the demarcation zone and no significant blood loss. The resection area was sutured in 1 case (20 %). In 2 individuals (40 %), a hemostatic sponge was installed in the removed tumor bed. In the remaining 2 cases (40 %), hemostasis was ensured by coagulation. The median blood loss was 100 mL (range: 50-200 mL). The postoperative period was uneventful in all patients. None of the patients developed symptoms of acute renal failure.Conclusion. Thus, superselective embolization of arteries supplying a kidney tumor has undeniable advantages in organ-sparing surgeries for patients with localized kidney cancer and some additional kidney problems, when organ preservation is crucial for patient's life.
Long-term treatment outcomes of patients with non-clear cell renal cell carcinoma
Authors: Mukhomedyarova A. A. , Alekseev B. Ya. , Kalpinskiy A. S. 
Published: November 2021

Objective: to analyze factors affecting relapse-free and overall survival of patients with non-metastatic non-clear cell renal cell carcinoma (nccRCC) after surgical treatment.Materials and methods. This study included 279 (13.62 %) nccRCC patients from the database containing information on 2049 patients with localized and locally advanced renal cell carcinoma (RCC) without distant metastases who underwent surgical treatment in the Department of Urologic Oncology, P.A. Herzen Moscow Oncology Research Institute between 2002 and 2018. Gender ratio was 1.36:1 (161 men (57.7 %) and 118 women (42.3 %)). Median follow-up time was 34.5 months (range: 1-141 months). Patients had undergone either radical nephrectomy (n = 117; 41.9 %) or kidney resection (n = 160; 57.4 %) or radiofrequency thermal ablation (n = 2; 0.7 %). Standard (open) transperitoneal approach was used in 135 patients (48.4 %) patients, whereas 144 (51.6 %) patients were operated on via laparoscopic approach. Postoperative histological examination demonstrated that 110 participants (39.4 %) had chromophobe RCC, while 79 (28.3 %) and 63 (22.6 %) individuals had type 1 and type 2 papillary RCC, respectively. Twenty-seven patients were found to have rare or mixed variants of nccRCC (they were excluded from the analysis due to their relatively small number). Patients were diagnosed with the following stages of cancer: рТ1а (n = 129; 46.2 %), pT1b (n = 72; 25.8 %), рТ2а (n = 18; 6.5 %), pT2b (n = 8; 2.9 %), рТ3а (n = 31; 11.1 %), pT3b (n = 4; 1.4 %), рТ4 (n = 1; 0,4 %), and pN+ (n = 16; 5.7 %).Results and conclusion. 13 patients (4.7 %) were diagnosed progressive disease; 9 patients (3.2 %) died due to nccRCC progression. The highest relapse-free and overall survival rates were registered in the patients with type 1 papillary RCC and chromophobe RCC.Spearman's correlation analysis showed a significant correlation between the risk of disease progression and tumor size (R = 0.23; p <0.0001), pT stage (R = 0.24; p = 0.0001), vascular invasion (R = 0.36; p <0.0001), pN+ stage (R = 0.4; p <0.0001), surgical resection margin (R = 0.5; p <0.0001), histological variant (R = 0.14; p = 0.02), and Furman differentiation grade (R = 0.16; p = 0.02). The following factors were found to have an impact on relapse-free survival according to multivariate Cox regression: presence of necrosis (p = 0.04), pT stage (p = 0.03), and vascular invasion (p = 0.08), although the last variable failed to reach statistical significance. Cancer-specific survival was significantly affected by pT stage (p = 0.01) and Furman differentiation grade (p = 0.04). None of the factors demonstrated significant associations with overall survival. Thus, the most significant prognostic factor affecting relapse-free, overall, and cancer-specific survival in nccRCC patients was the pT stage (p <0.05).
Renal failure in patients with hematological malignancies (literature review)
Authors: Gromova E. G. 
Published: November 2021

Dysfunction of the natural detoxification organs remains a significant problem in patients with hematological malignancies. The reasons for the development of renal failure are associated with the individual characteristics of the malignant process, the patient’s comorbid background, the toxic effects of anticancer treatment and its complications. The efficacy of many anticancer drugs correlates with their dose, an increase in which is associated with increased toxic effects on healthy organs, including the kidneys. The main reasons for the renal failure development in hematological cancer patients and syndromes that prevent adequate antitumor therapy are considered. Diagnostic algorithm optimization and supportive intensive care of acute renal failure is the key to the successful application of highly effective modern protocols of drug anticancer treatment.A special group is represented by patients suffering from monoclonal gammopathies with acute renal injury and hyperproduction of immunoglobulins free light chains. Renal failure can be the onset and dominant clinical manifestation of multiple myeloma in 18–56 % of cases, of which 10 % require programmed hemodialysis. Antitumor therapy in presence of renal failure is limited, and in some cases impossible, while the renal function recovery is associated with an increase in survival.Organ damage in oncohematological patients can be a manifestation of paraneoplastic syndromes. Tumor lysis syndrome is an urgent problem of oncohematological practice associated with the development of acute renal injury and high mortality.The development of organ failure in oncohematological patients causes significant difficulties in antitumor therapy; a combination of organ dysfunction and the resulting change in anticancer therapy regimens worsen the prognosis. Modern methods of organ failure prevention and treatment can successfully solve complex clinical problems.
Canada’s Economy in 2021: Exiting the “Pandemic” Recession
Authors: Nemova Lyudmila 
Published: November 2021

The article analyses the dynamics of the Canadian economy in 2020-2021, during the unprecedented global “pandemic” recession. It is shown that like in many other countries, the economic ups and downs in Canada closely followed the waves of the COVID-19 infection spreading across the regions and the subsequent rounds of regulatory restrictions on “high-contact” economic activities, citizens’ travel inside and outside the country, international trade, and etc. In the latter half of the 2020 several goods-producing industries showed signs of recovery which continued through the following year. However, it was only mass vaccination of Canadians in all provinces and territories that created conditions for sustained re-opening of businesses in most sectors of the national economy by the end 2021. The author looks at the internal and external drivers of recovery and continued growth. It is shown that on the whole the federal emergency plan proved to be successful in providing income support for Canadians and preventing bankruptcies among small and medium-sized businesses. The 2021 Federal Budget includes more than $100 billion in new spending over three years. It is expected that massive fiscal stimulus coupled with pent-up demand will sustain strong consumer spending after the speedy vaccine rollout allows businesses to fully reopen. At the same time, non-residential capital expenditures by private sector companies will increase only moderately in most sectors after a sizable decline in 2020. This year Canada’s resource-based industries are benefiting from the growing global demand for oil and gas, base metals, forest and agricultural products. The concluding part of the article analyses the major risks which can slow the economic recovery: the global supply-chain bottlenecks, labour market imbalances, growing inflation pressures, and massive federal budget deficit.
PEMANFAATAN BUKU OLEH MAHASISWA SEBAGAI PENUNJANG AKTIVITAS AKADEMIK DI ERA GENERASI MILENIAL
Authors: Prajawinanti Arin 
Published: November 2021

Mahasiswa merupakan calon intelektual masa depan generasi bangsa. Mahasiswa harus bisa menjalankan perannya sebagai pencipta perubahan. Mereka membutuhkan sumber informasi untuk menunjang seluruh aktivitas akademiknya. Di era sekarang ini sumber informasi tersedia dalam berbagai bentuk, apalagi didorong dengan adanya ledakan informasi saat ini. Pemilihan sumber informasi yang dilakukan oleh mahasiswadilakukan dengan adanya berbagai pertimbangan rasional dan juga motivasi yang dimiliki oleh mahasiswa untuk mencapai tujuan. Adanya dorongan dari luar seperti dukungan dari dosen atau lingkungan sekitar juga memiliki peran penting dalam mempengaruhi pilihan sumber informasi yang digunakan. Di lingkungan generasi milenial saat ini masih banyak mahasiswa yang memilih memanfaatkan buku untuk menunjang aktivitas akademiknya. Selain buku mahasiswa juga memanfaatkan sumber informasi dari jurnal. Kata Kunci: Pemanfaatan buku, pilihan rasional, motivasi