bluuebunny/crossref_metadata_2025_split huggingface dataset:
Do we eat what we buy? Relative validity of grocery purchase data as an indicator of food consumption in the LoCard study
Authors: Vepsäläinen Henna , Nevalainen Jaakko , Kinnunen Satu , Itkonen Suvi Tuulikki , Meinilä Jelena , Männistö Satu , Uusitalo Liisa , Fogelholm Mikael , Erkkola Maijaliisa 
Published: October 2021

AbstractThe validity of grocery purchase data as an indicator of food consumption is uncertain. This paper investigated (1) the associations between food consumption and grocery purchases using automatically accumulated purchase data and (2) whether the strength of the associations differed in certain sub-populations. The participants filled in a FFQ, and a major Finnish retailer issued us with their loyalty-card holders’ grocery purchase data covering the 1- and 12-month periods preceding the FFQ. We used gamma statistics to study the association between thirds/quarters of FFQ and grocery purchase data (frequency/amount) separately for eighteen food groups among the 11 983 participants. Stratified analyses were conducted for subgroups based on sex, family structure, educational level, household income and self-estimated share of purchases from the retailer. We also examined the proportion of participants classified into the same, adjacent, subsequent and opposite categories using the FFQ and purchase data. The gammas ranged from 0·12 (cooked vegetables) to 0·75 (margarines). Single households had stronger gammas than two-adult families, and participants with > 60 % of purchases from the retailer had stronger gammas. For most food groups, the proportion of participants classified into the same or adjacent category was > 70 %. Most discrepancies were observed for fresh/cooked vegetables, berries and vegetable oils. Even though the two methods did not categorise all food groups similarly, we conclude that grocery purchase data are able to describe food consumption in an adult population, and future studies should consider purchase data as a resource-saving and moderately valid measure in large samples.
The impact of food addiction behaviours on the treatment of overweight students
Authors: de Almeida Viviane Bellucci Pires , Filgueiras Andrea Rocha , Nogueira Paulo Cesar Koch , Sesso Ricardo Cintra , Sawaya Ana Lydia , Domene Semíramis Martins Álvares 
Published: October 2021

AbstractThe present study evaluated the association of food addiction (FA), the change of the BMI/agez-score and the consumption of ultra-processed foods in overweight students undergoing a 16-month, multicomponent intervention in the school environment. FA was investigated using the Yale Food Addiction Scale for Children, and the dietary assessment was estimated using the semi-quantitative FFQ in overweight 9–11-year-old students (BMI/agez-score ≥ 1) of both sexes at their baseline and after the intervention (n120). Among the schoolchildren, 33·4 % had FA in at least one of the two assessments. The analysis of mixed-effects models to assess the effect of the intervention and the change of the BMI/agez-score between evaluations showed that the occurrence of FA influenced the maintenance of weight (time#FA,β= 0·30, 95 % CI 0·05, 0·54,P= 0·016). Weight loss was observed only in individuals who did not present FA (BMI/agez-score = −0·3). When evaluating the effect of the intervention and the dietary variables, we verified a reduction in the consumption of sugary milk-based drinks −71·13 kJ (–17 kcal),P= 0·04 only in non-FA students at the end of the study. FA has been identified as an underlying factor with therapeutic relevance, and an enhanced understanding of FA can open new paths for the prevention and management of obesity.
Formation of ultrapotassic magma via crustal contamination and hybridization of mafic magma: an example from the Stomanovo monzonite, Central Rhodope Massif, Bulgaria
Authors: Marchev Peter , Raicheva Raya , Georgiev Stoyan , Savov Ivan P. , Jelev Danko 
Published: October 2021

AbstractGenerally all orogenic ultrapotassic rocks are formed after melting of metasomatized sub-continental lithospheric mantle via subducted crustal mica-bearing lithologies. Here we present another possible model, based on the study of the small Stomanovo ultrapotassic monzonite porphyry intrusion in the Central Rhodope Massif, Bulgaria. The monzonite dated at 30.50 ± 0.46 Ma is intruded into the voluminous Oligocene (31.63 ± 0.40 Ma) Bratsigovo–Dospat ignimbrite. The monzonite hosts both normally and reversely zoned clinopyroxene phenocrysts. The normally zoned clinopyroxene is characterized by gradually diminishing core-to-rim Mg no. (89–74), whereas the reversely zoned clinopyroxene has green Fe-rich cores (Mg no. 71–55) mantled by normally zoned clinopyroxene (Mg no. 87–74). Neither the core of the normally zoned clinopyroxene nor the Fe-rich green cores are in equilibrium with the host monzonite. This ultrapotassic monzonite shows more radiogenic Sr isotopes ((87Sr/86Sr)i= 0.71066) and ϵNd(t) = −7.8 to −8.0 that are distinct from the host ignimbrites with (87Sr/86Sr)i= 0.70917–0.70927 and ϵNd(t) = −4.6 to −6.5. The Sr–Nd isotopic data and the presence of copious zircon xenocrysts from the underlying metamorphic basement suggest extensive crustal assimilation. Our observations indicate that the Stomanovo ultrapotassic monzonite formed after extensive lower or middle crustal fractional crystallization from an evolved magma producing cumulates. The process was followed by hybridization with primitive mantle-derived magma and subsequent continuous crustal contamination. We suggest that instead of inheriting their high K2O and large-ion lithophile element enrichments from slab-derived/metasomatic fluids, the Stomanovo ultrapotassic monzonite may owe some of its unusually high alkalinity to the assimilation of potassium-rich phases from the Rhodope Massif basement rocks.
First report of post-cyclic transmission in trematodes: Derogenes lacustris (Digenea: Hemiuroidea) in Patagonian freshwater fishes
Authors: Tsuchida Karin , Rauque Carlos , Viozzi Gustavo , Flores Verónica , Urabe Misako 
Published: October 2021

AbstractThe transmission of adult parasites from prey to predatory hosts has been demonstrated for some acanthocephalan and one cestode species. Derogenes lacustris (Digenea: Hemiuroidea: Derogenidae) is a generalist parasite that infects, as an adult, the stomach of native and introduced freshwater fishes in Andean Patagonia. In the present work, the post-cyclic transmission of D. lacustris from native Galaxias maculatus (Galaxiidae) to introduced Oncorhynchus mykiss (Salmonidae) was proved experimentally. The observed transmission rate for this experimental infection was 19%. The body length of D. lacustris on day 14 post-infection was significantly greater than before transmission. The number of eggs also increased significantly after transmission, showing that D. lacustris can survive, grow and continue with egg production for at least 2 weeks in predatory salmonids. This study provides the first experimental evidence of post-cyclic transmission of trematodes and the results suggest that post-cyclic parasitism enables this species to broaden its range of hosts and distribution ranges in Argentinean Patagonia.
Assessing the genetic diversity of the metacercariae of Posthodiplostomum minimum (Trematoda: Diplostomidae) in Middle American freshwater fishes: one species or more?
Authors: Pérez-Ponce de León Gerardo , Sereno-Uribe Ana L. , Pinacho-Pinacho Carlos D. , García-Varela Martín 
Published: October 2021

AbstractTrematode taxonomy is mainly based on the morphological traits of adults. The identification of metacercariae is challenging because such traits are not developed in larval forms, and they even may show some level of morphological variability. Studies testing the potential correspondence between morphological differences and genetic variation of parasites are still lacking. The metacercariae of Posthodiplostomum minimum are probably the diplostomids more widely distributed in North and Middle American freshwater fish, and their intraspecific morphological variability has been attributed to the effect exerted by the host. Here, we tested the hypothesis whether they represent a single species, or a species complex by assessing the genetic divergence and phylogenetic relationships of metacercariae sampled from several host species in a wide geographical range across Middle America. The internal transcribed spacers (ITS1-5.8S-ITS2), and the mitochondrial COI gene were sequenced for 124 and 55 metacercariae, respectively. Phylogenetic analysis inferred from ITS sequences uncovered six well-supported monophyletic lineages. The six lineages show no correspondence to any Posthodiplostomum species for which sequences are available thus far in GenBank. Lineages exhibit some degree of host specificity; Lineages I, II, IV and V are primarily parasites of cyprinodontiforms of the families Poeciliidae, Goodeidae, Profundulidae and Fundulidae. In poeciliids there are at least four candidate species of Posthodiplostomum, some of them occurring in sympatry; instead, Lineages II and VI are exclusively parasites of cichlids. This study contributes to our understanding of the diversity of larval forms of diplostomids and provides an opportunity to further study their life cycles.
Finding Antarctica’s Pole of Inaccessibility
Authors: Rees Gareth , Gerrish Laura , Fox Adrian , Barnes Richard 
Published: October 2021

Abstract
Antarctica’s Pole of Inaccessibility (Southern Pole of Inaccessibility (SPI)) is the point on the Antarctic continent farthest from its edge. Existing literature exhibits disagreement over its location. Using two revisions of the Scientific Committee on Antarctic Research’s Antarctic Digital Database, we calculate modern-day positions for the SPI around 10 years apart, based on the position of the “outer” Antarctic coastline, i.e. its boundary with the ocean. These show that the position of the SPI in the year 2010 was around 83° 54’ S, 64° 53’ E, shifting on the order of 1 km per year as a result of changes of a similar magnitude in the Amery, Ronne-Filchner and Ross Ice Shelves. Excepting a position of the SPI calculated by British Antarctic Survey in 2005, to which it is very close, our newly calculated position differs by 150–900 km from others reported in the literature. We also consider the “inner” SPI, defined by the coastline with floating ice removed. The position of this SPI in 2010 is estimated as 83°37’ S, 53° 43’ E, differing significantly from other reported positions. Earlier cartographic data are probably not sufficiently accurate to allow its rate of change to be calculated meaningfully.
Effect of operating parameters of a magnetically controlled spiral capsule robot on its performance
Authors: Liang Liang , Tang Puhua , Liu Yu , Xu Yan 
Published: October 2021

AbstractA magnetically controlled spiral capsule robot is designed. When the robot is running in a pipe filled with mucus, computational fluid dynamics is used to analyze the fluid field (velocity, streamlines, and vorticity) in the pipe, and particle image velocimetry is used to measure the above fluid field surrounding the robot. The measured fluid field is basically similar to the numerical result. The relationship between the operating parameters of the robot and the performance of the robot is further calculated and analyzed. The results show that the resistance to the robot in the forward direction, average turbulent intensity of the fluid surrounding the robot, and maximum fluid pressure to the pipe wall are proportional to the robotic translational speed. The resisting moment of the robot in the forward direction, average turbulent intensity of the fluid surrounding the robot, and maximum fluid pressure to the pipe wall are proportional to the robotic rotational speed.
Association of subcortical gray-matter volumes with life-course-persistent antisocial behavior in a population-representative longitudinal birth cohort
Authors: Carlisi Christina O. , Moffitt Terrie E. , Knodt Annchen R. , Harrington HonaLee , Langevin Stephanie , Ireland David , Melzer Tracy R. , Poulton Richie , Ramrakha Sandhya , Caspi Avshalom , Hariri Ahmad R. , Viding Essi 
Published: October 2021

AbstractNeuropsychological evidence supports the developmental taxonomy theory of antisocial behavior, suggesting that abnormal brain development distinguishes life-course-persistent from adolescence-limited antisocial behavior. Recent neuroimaging work confirmed that prospectively-measured life-course-persistent antisocial behavior is associated with differences in cortical brain structure. Whether this extends to subcortical brain structures remains uninvestigated. This study compared subcortical gray-matter volumes between 672 members of the Dunedin Study previously defined as exhibiting life-course-persistent, adolescence-limited or low-level antisocial behavior based on repeated assessments at ages 7–26 years. Gray-matter volumes of 10 subcortical structures were compared across groups. The life-course-persistent group had lower volumes of amygdala, brain stem, cerebellum, hippocampus, pallidum, thalamus, and ventral diencephalon compared to the low-antisocial group. Differences between life-course-persistent and adolescence-limited individuals were comparable in effect size to differences between life-course-persistent and low-antisocial individuals, but were not statistically significant due to less statistical power. Gray-matter volumes in adolescence-limited individuals were near the norm in this population-representative cohort and similar to volumes in low-antisocial individuals. Although this study could not establish causal links between brain volume and antisocial behavior, it constitutes new biological evidence that all people with antisocial behavior are not the same, supporting a need for greater developmental and diagnostic precision in clinical, forensic, and policy-based interventions.
SARS-CoV-2 infection induced thyroid storm and heart failure in an adolescent girl
Authors: Das Bibhuti B. , Shakti Divya , Akam-Venkata Jyothsna , Obi Obiageli , Weiland Michael D. , Moskowitz William 
Published: October 2021

AbstractWe report a case of thyroid storm precipitated by SARS-CoV-2 infection in an adolescent girl with a history of Graves disease and dilated cardiomyopathy. This case highlights that SARS-CoV-2 infection can potentially trigger a thyrotoxicosis crisis and acute decompensated heart failure in a patient with underlying thyroid disease and myocardial dysfunction even in the absence of multi-system inflammatory syndrome in children. We systematically reviewed the thyrotoxicosis cases with SARS-CoV-2 infection and described its impact on pre-existing dilated cardiomyopathy.
Adaptations of paediatric cardiology practice during the COVID-19 pandemic
Authors: Fremed Michael A. , Niaz Talha , Hope Kyle D. , Altman Carolyn A. , Levy Victor Y. , Glickstein Julie S. , Johnson Jonathan N. 
Published: October 2021

AbstractDuring the initial surge of the COVID-19 pandemic in the spring and summer of 2020, paediatric heart centres were forced to rapidly alter the way patient care was provided to minimise interruption to patient care as well as exposure to the virus. In this survey-based descriptive study, we characterise changes that occurred within paediatric cardiology practices across the United States and described provider experience and attitudes towards these changes during the pandemic. Common changes that were implemented included decreased numbers of procedures, limiting visitors and shifting towards telemedicine encounters. The information obtained from this survey may be useful in guiding and standardising responses to future public health crises.
Vortioxetine 20 mg/day in patients with major depressive disorder: updated analysis of efficacy, safety, and optimal timing of dose adjustment
Authors: Christensen Michael Cronquist , McIntyre Roger S. , Florea Ioana , Loft Henrik , Fagiolini Andrea 
Published: October 2021

AbstractBackgroundAnalysis of efficacy and tolerability of vortioxetine 20 mg/day, and optimal timing of dose adjustment, in patients with major depressive disorder (MDD).MethodsPooled analysis of six randomized, fixed-dose studies of vortioxetine 5 to 20 mg/day. Mean change from baseline in Montgomery–Åsberg Depression Rating Scale (MADRS) total score was analyzed by vortioxetine dose using a mixed model for repeated measures. Tolerability was assessed over the 8-week treatment period and from day 8 (ie, following dose increase to 20 mg/day). Data from three randomized, flexible-dose studies were examined for frequency and timing of dose adjustment.ResultsA clear dose–response relationship for vortioxetine was confirmed in terms of improvement in MADRS total score. Significant differences vs placebo were seen for vortioxetine 20 mg/day from week 2 onwards; vortioxetine 10 mg did not separate from placebo until week 4. At week 8, mean change in MADRS total score from baseline was significantly greater for vortioxetine 20 mg/day vs 10 mg/day (difference, −1.03 points; P < .05). Incidence of adverse events was not increased in patients who received vortioxetine 20 mg/day vs 10 mg/day. In flexible-dose studies, dosage was increased to 20 mg/day after 1 week in 48.0% of patients; final dosage was 20 mg/day in 64.3% of patients.ConclusionsVortioxetine 20 mg is significantly more effective than vortioxetine 10 mg in patients with MDD, with a similar tolerability profile. In flexible-dose studies, almost half of all patients received 20 mg/day after 1 week and two-thirds received 20 mg/day as their final dosage.
Telephone-delivered Interpersonal Psychotherapy: a systematic review
Authors: Miniati Mario , Marzetti Francesca , Palagini Laura , Conversano Ciro , Buccianelli Beatrice , Marazziti Donatella , Gemignani Angelo 
Published: October 2021

AbstractBackgroundThe aim of this paper is to review evidence on Interpersonal Psychotherapy (IPT) administered via telephone (IPT-T).MethodsWe conducted a systematic review of studies published between January 1, 1990 and June 30, 2020, assessing the efficacy of IPT administered by phone, using PubMed.ResultsOriginally, we found 60 papers; the final selection led to 13 papers. Six studies were performed using a randomized clinical trial methodology (6/13, 46.2%), three were prospective open-label not randomized studies (3/13, 15.7%), three were pilot studies (3/13, 23.1%), and one was a feasibility/acceptance study (1/13, 7.7%). The number of subjects included in the studies ranged between 14 and 442 (mean: 140.0 ± 124.9), for a total of 1850 patients. The mean age of the enrolled subjects was 47.8 ± 9.3 years (range: 27.4-70.4). Thirty-four different instruments were utilized. Qualitative synthesis was conducted only on randomized controlled trials (RCTs), namely on six studies. RCTs were almost all of good quality (mean score/standard deviation of the RCT-Psychotherapy Quality Rating Scale omnibus rating: 5.6 ± 1.2 points; range: 3-7).ConclusionsIPT-T showed response rates similar to IPT administered in the usual way. Results are limited by small samples sizes, selection bias of the less severe depressed patients, and the heterogeneity of rating scales.
Modifiable predictors of suicidal ideation during psychotherapy for late-life major depression. A machine learning approach
Authors: Alexopoulos George S. , Raue Patrick J. , Banerjee Samprit , Mauer Elizabeth , Marino Patricia , Soliman Mohamed , Kanellopoulos Dora , Solomonov Nili , Adeagbo Adenike , Sirey Jo Anne , Hull Thomas D. , Kiosses Dimitris N. , Areán Patricia A. 
Published: October 2021

AbstractThis study aimed to identify subgroups of depressed older adults with distinct trajectories of suicidal ideation during brief psychotherapy and to detect modifiable predictors of membership to the trajectories of suicidal ideation. Latent growth mixed models were used to identify trajectories of the presence of suicidal ideation in participants to a randomized controlled trial comparing Problem Solving Therapy with “Engage” therapy in older adults with major depression over 9 weeks. Predictors of membership to trajectories of suicidal ideation were identified by the convergence of four machine learning models, i.e., least absolute shrinkage and selection operator logistic regression, random forest, gradient boosting machine, and classification tree. The course of suicidal ideation was best captured by two trajectories, a favorable and an unfavorable trajectory comprising 173 and 76 participants respectively. Members of the favorable trajectory had no suicidal ideation by week 8. In contrast, members of the unfavorable trajectory had a 60% probability of suicidal ideation by treatment end. Convergent findings of the four machine learning models identified hopelessness, neuroticism, and low general self-efficacy as the strongest predictors of membership to the unfavorable trajectory of suicidal ideation during psychotherapy. Assessment of suicide risk should include hopelessness, neuroticism, and general self-efficacy as they are predictors of an unfavorable course of suicidal ideation in depressed older adults receiving psychotherapy. Psychotherapeutic interventions exist for hopelessness, emotional reactivity related to neuroticism, and low self-efficacy, and if used during therapy, may improve the course of suicidal ideation.
Spontaneous traveling waves naturally emerge from horizontal fiber time delays and travel through locally asynchronous-irregular states
Authors: Davis Zachary W. , Benigno Gabriel B. , Fletterman Charlee , Desbordes Theo , Steward Christopher , Sejnowski Terrence J. , H. Reynolds John , Muller Lyle 
Published: October 2021

AbstractStudies of sensory-evoked neuronal responses often focus on mean spike rates, with fluctuations treated as internally-generated noise. However, fluctuations of spontaneous activity, often organized as traveling waves, shape stimulus-evoked responses and perceptual sensitivity. The mechanisms underlying these waves are unknown. Further, it is unclear whether waves are consistent with the low rate and weakly correlated “asynchronous-irregular” dynamics observed in cortical recordings. Here, we describe a large-scale computational model with topographically-organized connectivity and conduction delays relevant to biological scales. We find that spontaneous traveling waves are a general property of these networks. The traveling waves that occur in the model are sparse, with only a small fraction of neurons participating in any individual wave. Consequently, they do not induce measurable spike correlations and remain consistent with locally asynchronous irregular states. Further, by modulating local network state, they can shape responses to incoming inputs as observed in vivo.
Data-driven simulation and characterisation of gold nanoparticle melting
Authors: Zeni Claudio , Rossi Kevin , Pavloudis Theodore , Kioseoglou Joseph , de Gironcoli Stefano , Palmer Richard E. , Baletto Francesca 
Published: October 2021

AbstractThe simulation and analysis of the thermal stability of nanoparticles, a stepping stone towards their application in technological devices, require fast and accurate force fields, in conjunction with effective characterisation methods. In this work, we develop efficient, transferable, and interpretable machine learning force fields for gold nanoparticles based on data gathered from Density Functional Theory calculations. We use them to investigate the thermodynamic stability of gold nanoparticles of different sizes (1 to 6 nm), containing up to 6266 atoms, concerning a solid-liquid phase change through molecular dynamics simulations. We predict nanoparticle melting temperatures in good agreement with available experimental data. Furthermore, we characterize the solid-liquid phase change mechanism employing an unsupervised learning scheme to categorize local atomic environments. We thus provide a data-driven definition of liquid atomic arrangements in the inner and surface regions of a nanoparticle and employ it to show that melting initiates at the outer layers.