bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strategi Pemerintah Dalam Pengembangan Wisata Budaya Dan Kearifan Lokal Di Kabupaten Majene
Authors: Hartaman Nursaleh , Wahyuni Wahyuni , Nasrullah Nasrullah , Has Yusril , Hukmi Rezki Aitul , Hidayat Wahyuda , Ikhsan Andi Ahmar Ihwal 
Published: October 2021

Potensi budaya dan kearifan lokal merupakan pengembangan pariwisata dan menjadi bagian dari produk kreativitas masyarakat yang memiliki nilai ekonomis. Tujuan penelitian ini untuk menganalisis pariwisata berbasis budaya dan kearifan lokal di Kabupaten Majene yang dikembangan dengan berbagai langkah strategis pemerintah daerah Majene. Metode penelitian yang digunakan adalah analisis kualitatif melalui obserasi secara langsung dan interview atau wawancara secara mendalam dengan pihak-pihak terkait penelitian yaitu Kepala Dinas Kebudayaan dan Pariwisata Kabupaten Majene. Budaya dan kearifan lokal khususnya di Kabupaten Majene, secara universal memiliki potensi wisata budaya yang dapat dikembangkan untuk meningkatkan pariwisata berbasis budaya lokal dan kearifan lokal. Strategi pengembangan wisata budaya lokal dengan pengemasan budaya lokal khususnya budaya lokal Kabupaten Majene dapat dijadikan media promosi dan pengenalan daerah destinasi wisata budaya dan kearifan lokal.
Eksistensi Ratam Bagi Penanaman Visi Dan Misi Prodi Teologi Hindu Di STAHN Mpu Kuturan Singaraja
Authors: I Wayan Kariarta  , Komang Heriyanti  , Ni Made Evi Kurnia Dewi  
Published: October 2021

Ratam activities in the Hindu Theology Study Program are held in the framework of campus life orientation for new students (maba). In the implementation of ratam activities there are efforts to build communication and familiarity between all academic communities in the Hindu Theology Study Program. The vision of the Hindu Theology Study Program is: "Superior and Dignified Study Program of Tri Kaya Parisudha character". While the mission of the Hindu Theology Study Program is 1) Organizing quality Hindu Theology education to produce graduates of character, superiority and dignity; 2) Conduct innovative research in the development and application of Hindu Theology. 3) Organize community service in the field of Hindu Theology. Understanding of the vision and mission of the Hindu Theology Study Program by all academic community contained in it, is the fundamental point that determines the success of the work program that has been established. The background of the ratam is to socialize the vision of the Hindu Theology Study Program mission and strengthen the sense of brotherhood for the academic community in the Hindu Theology Study Program. Through the socialization of vision and mission, it is hoped that it can strengthen the understanding of the values contained in the concept of Tri Kaya Parisudha and increase solidarity between academic community in Hindu Theology Study Program.
THE VALUE OF DIFFERENTIATION OF WEAK FORMS OF D ANTIGEN OF THE ERYTHROCYTE SYSTEM RHESUS IN CLINICAL TRANSFUSIOLOGY AND OBSTETRICS
Authors: Pavlyuk R. P. , Myronenko H. A. , Tymoshenko U. V. , Lavrovskaya L. N. 
Published: October 2021

Summary. The characteristics of variants of antigen D are important because their immunogenicity and, consequently, clinical value depend on them.
Objective. To identify weak forms of D antigen of the Rhesus erythrocyte system using available methods, to investigate their frequency and to determine a strategy for interpreting the rhesus status of the individual.
Materials and methods. Rhesus affiliation of 3501 blood donors was determined, RhD affiliation of 44 people was specified. The studies were performed in hemagglutination reactions on a plane, test tubes, indirect Coombs’ test, micromethod in gel with MCA anti-D IgM, anti-D IgG, anti-D/DVI IgM/IgG, standard universal reagent antirhesus and standard serum antirhesus.
Results and discussion. Dweak was defined 1 % among donors, which is no different from its frequency among Europeans. 40 of the 44 subjects had Dweak and were classified as RhD +, 2 – DVI + — as RhD–, taking into account the world practice of referring an individual with serologically weak D depending on the category of the subject.
Conclusions. Due to significant differences in the immune response of individuals with Dweak and Dpartial to D + antigenic stimulus, in-depth examination of their RhD status is appropriate to determine transfusion and obstetric tactics.
LIVER ECHINOCOCCOSIS: DIAGNOSIS AND SURGICAL TREATMENT EXPERIENCE
Authors: Shaprinsky V. A. , Vorovsky O. O. , Kamins’kyy О. О. , Verba A. V. , Formanchuk A. M. , Mironishen Yu. A. , Chernichenko A. I. 
Published: October 2021

Summary. The purpose: to analyze the results of treatment of patients with liver echinococcosis.
Materials and methods: results of treatment of 76 patients with echinococcosis of the liver were analyzed, women — 66 (86,8 %), men — 10 (13,2 %). Primary echinococcosis was detected in 73 (96,1 %) patients, secondary — in 3 (3,9 %). Among instrumental research methods, ultrasound and computed tomography examination were of diagnostic value. Single liver cysts were found in 66 (86,8 %) patients, multiple — in 10 (13,2 %). Among patients with solitary cysts, the right lobe was more often affected in 56 (73,7 %) patients than the left — 20 (26,3 %) cases. Echinococcosis complications were observed in 16 (21,1 %) patients. Among them, most often there were suppurations of the cyst — in 13 (17,1 %); a break of the cyst in the free abdominal cavity — in 1 (1,3 %), in the pleural cavity — 1 (1,3 %), in the biliary tract — in 1 (1,3 %). In 20 (26,3 %) cases, the operation was performed from the upper median access, in 46 (60,5%) — from oblique hypochondriac accesses by Kocher or by Fedorov. Pericystectomy was performed in 52 (68,4 %) patients, in 8 (10,5 %) patients had resections of liver segments with an echinococcal cyst, in 4 (5,3 %) — cyst opening with removal of contents and treatment of its cavity. Laparoscopic echinococectomy was used in 12 (15,8 %) patients. In the postoperative period, complications were observed in 16 (21,1 %) patients. The use of the welding electrocoagulator EK-300M «Swarmed» in the thermal rehabilitation of the walls of the residual cavity after echinococectomy allowed to reduce blood loss from (2200 ± 210) to (250 ± 50) ml, recurrences – with 2,8 up to 0 %. Before and after operation was performed antireсedive antiparasitic therapy with albendazole (Vormil) in two cycles of 28 days, separated by a 14-day break. The dose at body weight over 60 kg was 400 mg 2 times a day, and for less than 60 kg the drug was prescribed at a rate of 15 mg/kg/day.
Results. With the use of laparoscopic echinococectomy, intraoperative blood loss was reduced by 9 times (р=0,0001); duration of operation — 2 times (р>0,05), stay in hospital - 3,3 times (р=0,002). There were no fatal outcomes.
Conclusions. Pericystectomy is an effective operation for complete recovery and does not give recurrence of the disease. The use of a welding electrocoagulator and laparoscopic echinococectomy significantly improve the results of treatment of patients with parasitic liver cysts.
LAPAROSCOPY IN THE TREATMENT OF COLONIC DIVERTICULAR BLEEDING
Authors: Tymchuk O. B. , Kashtalyan M. A. , Shapovalov V. Yu. 
Published: October 2021

Summary. Objective. To analyze the experience of treatment of patients with diverticular disease of the colon, complicated by bleeding.
Materials and methods. Analyzed the treatment of 221 patients, hospitalized in the Military Medical Clinical Center of the Southern region of Odessa, who underwent 263 surgeries for diverticular disease of the colon and its complications. Intestinal bleeding as a cause of hospitalization was noted in 17 (7.6 %) patients.
Results and discussion. In 9 patients, bleeding was stopped by conservative methods. 8 patients underwent surgical treatment. The following surgical interventions were performed: laparoscopic left hemicolectomy (4), laparoscopic resection of the sigmoid colon (1), left hemicolectomy (3), righthemicolectomy (1). At laparoscopic left hemicolectomy the average duration of operation made (205 ± 12,5) min. The average duration of the postoperative period was (9.75 ± 1.2) days. The average duration of the postoperative period was (9.75 ± 1.2) days. With left-sided traditional hemicolec-tomy — the average duration of the operation — (215 ± 16.3) min, the average duration of the postoperative period — (14.5 ± 2.1) days.
Conclusions. Our experience showed the relative duration of surgery in both laparoscopic and «traditional» open, the duration of the postoperative period with laparoscopic intervention is lower, the intensity of pain and recovery time of bowel function in the group of patients who also performed laparoscopic surgery. compared to traditional access operations.
QUANTITATIVE EVALUATION OF SYMPTOMS OF CHRONIC VENOUS INSUFFICIENCY AFTER SURGICAL TREATMENT OF ACUTE VARICO-THROMBOPHLEBITISIN THE GREAT SAPHENOUS VEIN BASIN
Authors: Filip S. S. , Hadzheha I. I. 
Published: October 2021

Summary. Objective. Toquantify the symptoms of chronic venous insufficiency after surgical treatment of AVTF in the basin of the great saphenous vein.
Materials and methods. The results of treatment of 355 patients with AVTF in the basin of the great saphenous vein were quantified. Of these, 234 (65.9 %) patients underwent surgical treatment of AVTF. Depending on the location and method of treatment, patients were divided into seven groups.
Results. The overall clinical score before surgery ranged from (11.71±1.87) to (19.78±5.74) points, and 12 months after surgery it was highest in patients of group VII and amounted to (9.75 ± 2.89)points. Restriction of physical activity before surgery in patients with AVTF ranged from (1.13±0.21) to (2.82±0.38) points, and after 12 months — from (0.43±0.19) to (1.05±0.22) points . Assessing the severity of the disease on three components, the following results were obtained: in patients before surgery, the clinical score ranged from (10.21±2.55) to (20.51±6.43,6) months after it — from (5.27±0.78) to (13.44 ± 3.21), and after 12 months — from (2.59±0.76) to (8.24±2.17) points.
Conclusions. The obtained quantitative results of the assessment of symptoms of chronic venous insufficiency convincingly demonstrate the high efficiency and expediency of surgical treatment of AVTF in large subcutaneous vein pools in comparison with isolated conservative treatment, which allows to obtain good early and long-term results in most patients.
DIAGNOSTICS AND TREATMENT OF PURULENT ARTHRITIS OF THE STERNOCLAVICULAR JOINT
Authors: Tielushko Y. V. , Pertsov V. I. , Savchenko S. I. 
Published: October 2021

Summary. Inflammatory lesion of the sternoclavicular joint (SCJ) is a rare disease that requires surgical treatment. Traditional radiography reveals osteolysis and osteosclerosis, however, at the onset of the disease, such changes are absent. Difficulties in diagnosing this disease require further study of the problem and the development of new therapeutic and diagnostic approaches.
Aim of the work: to study the role of sonography in the diagnosis of purulent arthritis of SCJ and the choice of treatment tactics.
Materials and methods. Prospective single-center study of 28 cases of acute nonspecific arthritis of SCJ. The patients were divided into 2 groups: the first included patients who received drug therapy, the second included patients subject to surgical treatment.
Results and discussion. Ultrasound scanning of SCJ identified 3 sonographic variants of the lesion: exudative, destructive with synovial hyperperfusion, and destructive with synovial hypoperfusion.
The duration of hospital stay in both groups did not differ statistically: 12 (12; 13.5) vs 14 (12; 14) days, p = 0.194.
Analysis of long-term results in patients of the first group established the progression of the disease with the development of osteomyelitis or recurrence of arthritis in 3 cases (30 %). Among the patients of the second group, no complications or recurrence were detected during the indicated observation period.
Conclusion. Sonography is diagnostically significant in the diagnosis of SCJ arthritis. It allows you to determine the group of patients subject to mandatory surgical correction. Intravenous drug addiction associated with bacteremia is a predictor of poor drug treatment outcomes and an indication for active surgical tactics.
COVID-19-ASSOCIATED ACUTE LOWER LIMBS ISCHAEMIA IN ELDERLY AND SENILE PATIENTS: TREATMENT PROSPECTS (PRELIMINARY ANNOUNCEMENT)
Authors: Kanikovsky О. E. , Sander S. V. , Bondarchuk О. I. , Fedzhaha О. P. , Malyarchuk V. P. , Mosendz V. V. 
Published: October 2021

Summery. The aim — analysis of preliminary experience of treatment of COVID-19-associated acute lower limbs ischemia in elderly and senile patients.
Materials and methods. We examined 48 patients (age 60- 84 years). First group — 16 patients with COVID-19-associated acute lower limbs ischemia, second group — 32 patients with chronic limb ischemia without coronavirus infection. .
Results and discussion. First group’s patients had extended blood clotting time (more than 13-15 min). Other blood clotting indicators changed slightly. An isoline or a low-amplitude curve was recorded during photoplethysmography. After thrombectomy (6 patients) 3 patients had fatal thrombotic complications (PE, myocardial infarction, stroke), 1 had progressive ischemia. Pharmacotherapy was performed in 10 patients (in 2 patients later than 12 hours from the onset of ischemia). The effectiveness of timely started pharmacotherapy reached 67 %. All patients of group II had arteriosclerosis of the tibial arteries. Blood clotting indicators were normal. A high-amplitude curve was recorded during photoplethysmography. Thus, all elderly and senile patients has arteriosclerosis of the tibial arteries. On this basis, there was a fatal coincidence (coagulopathy, a sharp slowdown in blood flow, endothelial dysfunction) in case of coronavirus infection (COVID-19). Prospects for further developments are the improvement of anticoagulant therapy (for example, the simultaneous use of unfractionated and low molecular weight heparin) and improving of collateral circulation (for example, nerve block and forced intraarterial infusion or lavage).
Conclusion. Currently, the effectiveness of thrombectomy in elderly and senile patients with COVID-19-associated acute lower limbs ischemiа is 33 %, the effectiveness of timely started pharmacotherapy Is 67 %.
MODERN VIEWS ON THE TREATMENT OF PERFORATED PYLORODUODENAL ULCERS
Authors: Smetskov D. O. , Нoncharova N. M. , Teslenko S. M. , Svirepo P. V. , Sivozhelizov A. V. , Sikal M. O. , Нoncharov A. S. 
Published: October 2021

Summary. Purpose: to improve the results of surgical treatment of patients with perforated pyloroduodenal ulcer.
Materials and methods. The results of treatment of 101 patients operated on for perforated pyloroduodenal ulcer, which were treated in the surgical department for the period from 2015 to 2020, were analyzed.
Results and discussion. Laparoscopic interventions were performed in 56 (55.4 %) patients with perforated ulcer. Excision of perforated ulcer by traditional laparotomy without vagotomy was used in 26 (25.7 %) patients. Suturing of perforated ulcer by traditional method without vagotomy was performed in 19 (18.8 %) patients. Complications of the early postoperative period in 8 (7.9 %) patients were surgical in nature. In 27 (26.7 %) patients postoperative complications were specific associated with the performance of dilated pyloroduodenoplasty. The largest number of postoperative complications was observed in patients who underwent suturing of the ulcer using traditional laparotomy access – 17 (16.8 %), of which general surgery – 6 (5.9 %), specific – 11 (10.9 %).
Conclusions. Laparoscopic suturing of perforated ulcers is accompanied by less pronounced pain, a decrease in the number of postoperative complications, which requires greater use of endovideo-surgical technologies in this complication of peptic ulcer disease.
DIAGNOSIS OF TOXEMIA IN PATIENTS WITH LIVER CIRRHOSIS
Authors: Rusin A. V. , Malyar-Hazda N. M. , Balazh O. P. 
Published: October 2021

Abstract. The aim of the study. Assessment of the degree of toxemia in patients with liver cirrhosis with hepatic encephalopathy.
Materials and methods. The study involved 95 patients with LC who were hospitalized from 2018 to 2020 in the Department of Anesthesiology and Intensive Care, Surgical and Gastroenterological Departments of the Transcarpathian Regional Clinical Hospital. Andriy Novak (Uzhhorod). Using the method of complex toxicometry, studies of the mechanisms of formation and development of toxicosis were performed. To study the participation of toxins in the formation of autoimmune reactions, the content of lymphocytes that form rosettes with autologous erythrocytes was determined. The method of cytolytic activity of leukocytes was used to study the damaging effect of toxins on biological targets.
Results. According to the obtained data, in all studied patients with LC there was a significant increase in cytolytic and autoimmune activity of whole plasma. It was found that the highest levels of cytolytic activity were observed in patients with LC II and III groups (57.90 ± 2.27) and (56.50 ± 2.11) %, respectively; the smallest — in patients with LC III and I groups (49.8 ± 5.2) and (50.59 ± 2.12) %, respectively). In all patients with cirrhosis of the liver on protein toxin-bearing fractions (albumins, globulins) there was a predominant accumulation of toxins with a particle size of 10-200 nm.
Conclusions. In all patients with cirrhosis of the liver on protein toxin-bearing fractions (albumins, globulins) there was a predominant accumulation of toxins with a particle size of 10-200 nm. Toxins with particle sizes greater than 200 nm were found in patients with group III PE, which had a strong connection with protein toxin-bearing fractions. The highest levels of cytolytic activity were observed in patients with LC of groups II and III (57.90 ± 2.27) and (56.50 ± 2.11) %, respectively; the smallest — in patients with LC III and I groups (49.8 ± 5.2) and (50.59 ± 2.12) %, respectively. The highest level of autoimmune activity was found in patients of group II (52.41 ± 3.56) %; the lowest — in patients with cerebral palsy from group I (50.36 ± 3.2).
THE ROLE OF LAPAROSCOPIC CONTACT THERMOMETRY IN THE DIAGNOSIS OF EDEMATOUS ACUTE PANCREATITIS
Authors: Kapshitar A. V. , Kapshitar A. A. 
Published: October 2021

Summary. Objective: to identify the temperature of the abdominal organs and markers of the edematous form of acute pancreatitis using laparoscopic contact thermometry.
Material and methods. In 27 patients aged 28–76 years with suspected acute abdominal surgical diseases, laparoscopy was performed using a Karl Storz (Germany) apparatus using the improved Kelling technique and an edematous form of acute pancreatitis was suspected. To expand the diagnostic capabilities of the method, laparoscopic contact thermometry of the abdominal organs was performed using a TPEM-M electrothermometer and a designed probe with a sensor at the end.
Results. The highest temperature values were found in the area of the omentum (38.1 ± 0.2) °C), the mesentery root of the transverse colon (37.8 ± 0.16) °C and the lesser omentum (37.7 ± 0.13) °C. These anatomical regions are closest to the pancreas, where the pathological process develops. The highest temperature was found in the area of the stuffing box (38.1 ± 0.2) °C, and the lowest temperature was found in the appendix (36.4 ± 0.13) °C, which amounted to a temperature difference of 1.7 °C. The subsequent clinical course and the results of additional research methods confirmed the diagnosis of the edematous form of acute pancreatitis.
Findings. The highest temperature values obtained during laparoscopic contact thermometry of the abdominal organs in the area of the omental foramen, the mesentery root of the transverse colon and the lesser omentum are markers of the edematous form of acute pancreatitis.
APPLICATION OF GALVANOENTEROSORPTION IN MULTIMODAL TREATMENT OF PATIENTS WITH THERMAL BURNS
Authors: Khomko O. Y. , Petryuk B. V. , Khomko L. P. , Sydorchuk G. I. , Petryuk T. A. , Zazulia I. V. 
Published: October 2021

Abstract. Aim – to investigate the influence of enterosorption and its combination with intra-tissue electrophoresis (ITE) of antibacterial preparations on the proteolytic and fibrinolytic activity of blood plasma in patients with common thermal burns.
Material and methods. Enterosorbtion detoxification by enterosgel was used in the multimodal treatment of 28 patients with thermal burns of II-IV stages. The drug was prescribed from 2-3 days after burn for 7-14 days, depending on the severity of the injury and manifestations of the intoxication syndrome. In 24 patients the treatment was complemented by galvanization of burn wounds with the preliminary introduction of antibacterial drugs. ITE began with 3-4 days after burn, taking into account the sensitivity of the microflora to antibiotics. The comparison group was made up of 30 patients with similar areas and depths of thermal burns receiving traditional treatment.
Results and discussion. It was discovered that the inclusion of enterosorption in multimodal therapy of burns diminished the level of unlimited proteolysis, favoured the increase of the level of blood plasma fibrinolytic activity. Its combination with ITE of antibacterial agents (galvanoenterosorption) ensured a higher therapeutic effect. Common deep thermal burns are accompanied by a significant increase in proteolytic and fibrinolytic activity (FA) of blood. Inclusion of enterosorbtion in the integrated therapy of burns provides reduction of proteolytic activity and maintenance of a high level of FA of plasma, which reduces the risk of thromboembolic complications.
Conclusion. Combined use of enterosorption and ITE of antibacterial agents (galvanoentersorption) with thermal burns provides a higher therapeutic effect.
SURGICAL STRATEGY OF PATIENTS WITH STOMACH CANCER COMPLICATED WITH ACUTE GASTRIC BLEEDING
Authors: Boiko V. V. , Lazirskiy V. A. , Krivorotko I. V. 
Published: October 2021

Summary. Objective. Improvement of results of treatment of patients with stomach cancer complicated with acute gastric bleeding.
Materials and methods. It was shown the analysis of results of surgical treatment of 252 patients with stomach cancer complicated with acute gastric bleeding, which got the hospital treatment at GI “V. T. Zaycev Institute of General and Urgent Surgery of NAMS of Ukraine“ from 2010 till 2019, aged 29 till 76. All patients randomly divided on 2 groups: the group of control — 129 patients (got the hospital treatment from 2010 till 2014), and the basic group — 123 patients (from 2015 till 2019).
Results. The common surgical tactics and operations were used at the group of control. The two-staged active-idividualized surgical tactic was used at the basic group. Radical surgery was performed in 120 (47.6%) cases; in 132 (52,4%) cases – palliative and symptomatic(the 121(48,0%) cases of it was major abdominal surgery). Postoperative complications occurred in 79 patients (31.1%) and postoperative mortality in 7.9% (20 patients) cases.
Conclusion. There is the rational of using the two-staged surgical tactic with wide using of minimally invasive procedure for the treatment of patients with stomach cancer complicated with acute gastric bleeding. Using of this tactic leads to increasing of quantity of radical operations from 38(29,2%) at the group of control till 82(72,8%) at the basic group and leads to decreasing post-operative deaths from 8,5 % till 7,2 % respectively.