bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Using Mobile Applications on Health Outcomes in Patient Self-Management of Oral Anticoagulation Therapy
Authors: Moghaddasi Hamid , Haji Mohammadreza Naderi , Sharif-Kashani Babak , Kazemi Alireza 
Published: March 2021

Abstract
Background

Between one and two percent of the population of the developed countries are currently treated with oral anticoagulation therapy. The transition of all or part of the responsibility for therapy management to the patient is an appropriate strategy to respond increasing demand for oral anticoagulation therapy. The main objective of this original study was to investigate the impact of using mobile applications on health outcomes in patient self-management of oral anticoagulation therapy.
Methods

The papers reviewed in this study had two key characteristics: firstly, they were written in English, and secondly, they used mobile application in oral anticoagulation therapy. An Android mobile application called XrinA was developed to provide warfarin patient self-management. The study was conducted following a Before-After study design. In the Before and After periods, patients were treated as usual and by using the developed application, respectively.
Results

In the Before period, the mean percentage of International Normalized Ratios (INRs) within the therapeutic range and Time in Therapeutic Range (TTR) of patients was 31.63% and 34.4%, respectively. In the After period, the mean percentage of INRs within the therapeutic range and TTR of patients was 41.41% and 49.97%, respectively. In the After period, the mean INRs within the therapeutic range and the mean TTR increased by 9.78% and 15.57%, respectively.
Conclusions

Overall, the use of mHealth applications improved outcomes in patient self-management of oral anticoagulation therapy in terms of the percentage of INRs within the therapeutic range and TTR.
A Measure of Active Interfaces in Supported Catalysts for High-temperature Reactions
Authors: Lee Siwon , Ha Hyunwoo , Bae Kyung Taek , Kim Seunghyun , Choi Hyuk , Kim Jun Hyuk , Seo Jongsu , Choi Jin , Jo Yong-Ryun , Kim Bong-Joong , Lee Kang Taek , Kim Hyun You , Jung WooChul 
Published: March 2021

Abstract
Formulating knowledge of structure-function relationships in heterogeneous catalysis is central to the rational design of highly efficient catalysts, yet the elucidation of dominant reaction sites has remained as a grand challenge for researchers. Here, we present a novel methodology that can be used to visualize metal-gas and metal-oxide-gas interfaces in three dimensions and to quantify their catalytic activity levels. As a case study, CH4 oxidation occurring in a Pt/CeO2 system is chosen. By employing thermally robust Pt@CeO2 model catalysts with size-tunable and monodisperse cores, and gas-permeable shells, we reconstruct a series of heterogeneous structures in 3D via electron tomography and match the information precisely to catalytic activity data and theoretical calculations. This strategy reveals that the two different interfaces concurrently catalyze the CH4 oxidation and that their contribution to the overall reaction rate changes dynamically with respect to the Pt size, temperature, and gas atmosphere. Our results provide a new analytic platform on which to explore reaction pathways and mechanisms applicable to multiple reactions and materials.
Dynamics and Wave Propagation in Nonlinear Piezoelectric Metastructures
Authors: Mosquera-Sánchez Jaime Alberto , De Marqui Carlos 
Published: March 2021

Abstract
This paper reports dynamical effects in onedimensional locally resonant piezoelectric metastructures that can be leveraged by nonlinear electrical attachments featuring either combined quadratic and quartic, or essentially quartic potentials. The nonlinear electromechanical unit cell is built upon a linear host oscillator coupled to a nonlinear electrical circuit via piezoelectricity. Its dynamical response to prescribed longitudinal harmonic displacements is approached in the frequency and time domains. Semi-analytical harmonic balance (HB)-based dispersion relations are derived to predict the location and edges of the nonlinear attenuation band. Numerical responses show that weakly and moderately nonlinear piezoelectric metastructures (NPMSs) promote a class of nonlinear attenuation band where a bandgap and a wave supratransmission band coexist, while also imparting nonlinear attenuation at the resonances around the underlying linear bandgap. Besides, strongly nonlinear regimes are shown to elicit broadband chaotic attenuation. Negative capacitance (NC)-based essentially cubic piezoelectric attachments are found to potentiate the aforementioned effects over a broader bandwidth. Excellent agreement is found between the predictions of the HB based dispersion relations and the nonlinear transmissibility functions of undamped and weakly damped NPMSs at weakly and moderately nonlinear regimes, even in the presence of NC circuits. This research is expected to pave the way towards fully tunable smart periodic metastructures for vibration control via nonlinear piezoelectric attachments.PACS 05.45.-a . 62.30.+d . 62.65.+kMathematics Subject Classification (2010) 37N15 . 74H45 . 74H65 . 74J30
Can verbal autopsy improve the diagnostic accuracy of Physicians in Shanghai? Application of SmartVA
Authors: Chen Lei , Xia Tian , Rampatige Rasika , Li Hang , Adair Tim , Joshi Rohina , Gu Zhen , Yu Huiting , Fang Bo , McLaughlin Deirdre , Lopez Alan D. , Wang Chunfang , Yuan Zheng'an 
Published: March 2021

Abstract
Background

Accurate data on causes of death are essential for policy makers and public health experts to plan appropriate health policies and interventions to improve population health. Whereas approximately 30% deaths of Shanghai either occur at home or are not medically attended; the recorded cause of death in these cases may be less reliable than for a hospital death. Verbal Autopsy is a practical method that can help determine causes of death in regions where medical records are insufficient or unavailable. In this research, the smart VA tool was adopted to assign the cause of death of home deaths and to validate the accuracy and efficiency of the tool, the results were compared with routine practice to ascertain the value, if any, of incorporating VA into the diagnostic practices of physician in Shanghai certifying the cause of home deaths.
Methods

This pilot study selected home deaths certified by 16 community health centers from 3 districts represent urban, suburb, and urban-suburb areas in Shanghai, from December 2017 to June 2018. The medical records for all deaths for which a VA was carried out in these 3 districts during same period were carefully evaluated an independent Medical Record Review (MRR) team. Causes of death from both the SmartVA sample and the UCOD from the MRR were transformed to the SmartVA cause list for comparison. The concordance between the initial diagnosis and MRR UCOD and post-VA diagnosis and MRR UCOD was assessed using Chance Corrected Concordance.
Results

Overall CSMF accuracy improved from 0.93, based on the initial diagnosis, to 0.96 after the application of SmartVA. The misclassification of the initial diagnosis compared to that from the MRR. 86.3% of the initial diagnoses assigned the correct CODs, after the VA investigation, 90.5% of the post-VA diagnosis assigned the correct CODs.
Conclusions

Although Shanghai has an established and well-functioning CRVS system, SmartVA for Physicians contributed to an improvement in the accuracy of death certification. In addition, SmartVA may be a useful tool for inferring some special causes of death, such as those CODs classified as undetermined.
Does Radical trachelectomy (RT) during pregnancy have higher obstetrical and oncological risks than RT before pregnancy?
Authors: Shinkai Shota , Ishioka Shinichi , Mariya Tasuku , Fujibe Yuya , Kim Miseon , Someya Masayuki , Saito Tsuyoshi 
Published: March 2021

Abstract
Purpose
Radical trachelectomy (RT) with pelvic lymphadenectomy has become a new treatment option for young patients with uterine cervical cancer stages 1A2–1B1 who desire the preservation of their fertility. However, the application of RT for pregnant patients is still controversial. We comparatively studied both obstetrical and oncological outcomes of pregnant patients who underwent vaginal RT during pregnancy and those who underwent vaginal RT before pregnancy.
Methods
Both obstetrical and oncological results of eight patients who underwent vaginal RT with pelvic lymphadenectomy during pregnancy in our institute between 2010 and 2020 (Group A), and ten pregnant patients who underwent vaginal RT with pelvic lymphadenectomy before pregnancy during the same period (Group B) were reviewed based on their medical charts.
Results
There were no significant differences in blood loss, surgical time, or surgical completeness between Group A and Group B. Nor were there significant differences in obstetrical outcomes between the two groups. However, two of the eight patients in Group A had recurrence of the cancer. None of the patients in Group B has shown any signs of recurrence thus far.
Conclusion
Vaginal RT during pregnancy does not affect the obstetrical prognoses of patients with early invasive uterine cervical cancer, and it might be a tolerable treatment modality for them. However, oncologically, it should be performed carefully as there is a risk of recurrence.
Establishment of lightning detection sensors network in India: retrieval of essential climate variables and vulnerability mapping
Authors: Taori Alok , Suryavanshi Arun , Gharai Biswadip , Pawar Sunil , Seshasai M. V. R. 
Published: March 2021

Abstract
A network of 25 lightning detection sensors (LDS) has been established by National Remote Sensing Centre (NRSC), Indian Space Research Organization (ISRO). In the present network, sensors are located in the north-east, east coastal, central and southern locations of India. Geo-location of the lightning occurrences is estimated using time of arrival algorithm. Thus obtained lightning occurrences have been used to derive climate variables (ECVs) and to understand the vulnerable regions. We carry out overlay analysis on a Geographical Information System (GIS) platform on the monthly aggregate number of CG flash occurrences to identify the vulnerable Indian states during July 2019 to November 2020. We note that December-January reported the least number of cloud-to-ground (CG) flash occurrences while, August-September were the months with most number of CG flash occurrences. We also note that during the period under the scrutiny in this report, Chattisgarh, Jharkhand, Odisha, Maharashtra and Madhya Pradesh states recorded the most number of CG lightning flash occurrences.
Cost-utility analysis of olanzapine in four-drug antiemetic therapy in Japanese patients treated with highly emetogenic cisplatin-containing chemotherapy
Authors: Kondo Yu , Tachi Tomoya , Sakakibara Takayoshi , Kato Jun , Mizuno Takahito , Miyake Yoshio , Teramachi Hitomi 
Published: March 2021

Abstract
Purpose Olanzapine has been shown to have an additive effect on the three-drug antiemetic therapy, consisting of aprepitant, palonosetron, and dexamethasone, in a highly emetogenic cisplatin-containing chemotherapy. Although olanzapine may be more economical than aprepitant or palonosetron, an adequate cost-efficacy analysis has not been conducted. We conducted a cost-utility analysis to evaluate the cost-effectiveness of olanzapine in four-drug antiemetic therapy among Japanese patients.Methods We simulated model patients treated with highly emetogenic cisplatin-containing chemotherapy and developed a decision-analytical model of patients receiving triple antiemetic therapy with or without olanzapine. The cost, probabilities, and incremental cost-effectiveness ratio (ICER) of each treatment were calculated from the perspective of the Japanese healthcare payer. The threshold ICER was set at 45,867 United States dollars (USD) (5 million Japanese yen) per quality-adjusted life-year (QALY). The probabilities, utility value, and other costs were obtained from published sources. The robustness of this model was validated by one-way sensitivity analysis and probabilistic sensitivity analysis.Results The calculated ICER was 5,156 USD/QALY, which was below the threshold. Under the set conditions, the probabilistic sensitivity analysis revealed a 100% probability that olanzapine was cost-effective. Based on the one-way sensitivity analysis, reducing the cost of olanzapine below 10.78 USD placed the ICER below the threshold. Conclusion Olanzapine was cost-effective in the four-drug antiemetic therapy for Japanese patients treated with highly emetogenic cisplatin-containing chemotherapy
Temporal Change in Seismic Wave Attenuation Using High-stable Vibration Sources.
Authors: TSUJI Shuhei , Yamaoka Koshun , Ikuta Ryoya 
Published: March 2021

Abstract
We developed a method to detect attenuation changes during seismic wave propagation excited by precisely controlled artificial seismic sources, namely Accurately Controlled Routinely Operated Signal System (ACROSS), and applied it to monitor the temporal changes for in situ data collected by previous studies. Our method, together with the use of the ACROSS sources, is less susceptible to noise level changes, from which conventional methods such as envelope calculation suffer. The method utilizes the noise level that is independently estimated in the frequency domain and eliminates the influence of the noise from the observed signal. For performance testing, we applied this method to a dataset that was obtained in an experiment at Awaji Island, Japan, from 2000 to 2001. We detected a change in amplitude caused by rainfall, variation in atmospheric temperature, and coseismic ground motions. Among them, coseismic changes are of particular interest because there are limited studies on coseismic attenuation change, in contrast to many studies on coseismic velocity decrease. At the 2000 Western Tottori earthquake (MW = 6.6, epicenter distance of 165 km), a sudden decrease in amplitude of up to 5% was observed. The coseismic amplitude reduction and its anisotropic characteristics, which showed a larger reduction in the direction of the major axis of velocity decrease, were consistent with the opening of fluid-filled cracks, as proposed by previous studies. The W corresponding to the amplitude change gives similar values to those reported in previous studies using natural earthquakes.
COVID-19: Access to Information, Level of Trust and Adherence to Health Advice Among Migrants in Norway
Authors: Madar Ahmed A , Benavente Pierina , Czapka Elżbieta , Herrero-Arias Raquel , Haj-Younes Jasmin , Hasha Wegdan Hasha Wegdan , Deeb George , Møen Kathy A , Ortiz-Barreda Gaby , Diaz Esperanza 
Published: March 2021

Abstract
Background: Migrants in Norway bear a higher burden of COVID-19 infections and hospitalization as compared to non-migrants. The aim of our study was to understand migrants’: i) perception of health risk, ii) access to information, iii) degree of trust in and iv) adherence to recommendations.Methods: An online survey was performed between May and July 2020 among 529 Polish, Arabic, Somali, Tamil, and Spanish-speaking migrants. Unweighted and weighted descriptive analysis and chi-squared tests were performed for all migrants together and for each language group.Results: There were statistically significant differences among groups in their perception of risk of infection. Although the vast majority reported having received sufficient information, high level of adherence to preventive measures and trust in Norwegian authorities, there were statistically significant differences among groups regarding the importance of sources of information and level of trust, which was lowest for the Polish group. Over all, migrants reported very high adherence to preventive measures.Conclusion: Understanding how migrants are dealing with this pandemic is crucial to improve the dissemination of information and trust in the health authorities for the different groups.
Corneal Cross-linking for Keratoconus and Post-LASIK&nbsp;Ectasia and Failure Rate: A 3 Years Follow-up Study
Authors: CHANBOUR WASSEF , elzein lulwa , Younes Mohamad ali , issa mohamad , warhekar pramod , chalala elias , jarade elias 
Published: March 2021

Abstract
PURPOSE: To report the response of keratoconus(KC) and post-LASIK ectasia (referred as ‘’ectasia’’) to the corneal crosslinking(CXL) and to compare the rate of progression between KC and ectasia at 3 years.METHODS: Retrospective cohort study of patients undergoing CXL for either KC or ectasia. 54 eyes(31 patients) with ectasia and 111 eyes(67 patients) with KC were included in the study. Corrected distance Visual acuities(CDVA), refraction, keratometry(K) and pachymetry were followed over 3 years. Simultaneous Photorefractive keratectomy(PRK) and CXL was performed on 20 KC and 20 ectasia eyes. Intrastromal Corneal Ring Segments(ICRS) was performed on 51 KC and 6 ectasia eyes.RESULTS: In KC, CDVA, spherical equivalence, sphere, cylinder and mean K improved at 3 years post-CXL(p-value<0.05), but, these values improved without reaching a statistical significance in ectasia. 12 of 54 eyes with ectasia(22.2%) and 4 of 111 eyes(3.6%) with KC had progression post CXL(p-value:0.0001). Ectasia patients diagnosed with progression were older at presentation (36.1 years) than non-progressive ectasia patients(31 years)(p-value:0.02), and also older than KC patients.Sub-analysis excluding PRK and ICRS cases showed that there was an improvement in mean sphere (from -5.23±4.2D to-4.46±3.89D)(p-value:0.03) cylinder(from 2.54±1.68D to 1.97±1.51D)(p-value:0.03) mean keratometry(from 46.81±3.78D to 46.01±3.25D)(p-value:0.006) in KC patients 3 years post CXL(40patients). Compared to baseline, all the mean refractive and tomographic variables deteriorated at 3 years post CXL in ectasia(28 patients)(p-value>0.05). Also, 2 of 40 patients with KC(5%) vs. 7 of 28 patients with ectasia(25%) had progression 3 years post-CXL and the difference between both groups remained statistically significant(p-value:0.027). CONCLUSION: Eyes with post-LASIK ectasia seems to be less responsive to CXL than KC.
Sexual Assault and White Matter Hyperintensities Among Midlife Women
Authors: Thurston Rebecca , Jakubowski Karen , Wu Minjie , Aizenstein Howard , Chang Yuefang , Derby Carol , Koenen Karestan , Barinas-Mitchell Emma , Maki Pauline 
Published: March 2021

Abstract
Background
Traumatic experiences have been linked to poor mental and physical health. However, there has been little examination of their relationship to neuroimaging markers of cerebrovascular risk. White matter hyperintensities (WMHs) are markers of brain small vessel disease. WMHs can be detected decades before the onset of dementia and other disorders and can serve as early markers for these brain disorders. We tested whether traumatic experiences were associated with brain WMH volume among midlife women.
Methods
In the MsBrain study, 145 women (mean age = 59 years) without cardiovascular disease, stroke, or dementia were recruited. Women completed questionnaires [trauma checklist, depression, post-traumatic stress measures]; physical measures [body mass index (BMI), blood pressure (BP)]; phlebotomy; actigraphy sleep measurement, and 3 Tesla magnetic resonance brain imaging for WMHs. Cross-sectional associations between traumatic experiences and WMH volume were assessed in linear regression models. Covariates were age, race/ethnicity, education, BMI, BP, lipids, preeclampsia, sleep, and additionally depressive and post-traumatic stress disorder symptoms.
Results
68% of women endorsed at least one of the traumas assessed. The most common trauma was sexual assault (23% of women). Women with trauma exposure had greater WMH volume than women without trauma [B(SE) = .24 (.09), p = .01, multivariable]. The single trauma most associated with WMH was sexual assault [B(SE) = .25 (.11), p = .02, multivariable]. Results persisted adjusting for depressive or post-traumatic stress symptoms.
Conclusions
A trauma history, particularly sexual assault, was associated with greater WMH volume controlling for covariates, including depressive and post-traumatic symptoms. Sexual assault may place women at risk for poor brain health.
Improving Nurse’s Knowledge, Attitude and Practice Toward Nurse’s Role in Organ Donation Process in a Context-based Learning Course
Authors: Ahmady Soleiman , Hosseini Toktam Masoumian , Hosseini Mohsen Masoumian 
Published: March 2021

Abstract
Background: The Nurse’ knowledge, Attitude and Practice toward their roles in the Organ Donation Process are extremely important to the success of organ donation. Therefore, the nurses involved with this phenomenon should be aware of their roles. This study was conducted to investigate the effect of Context-Based Learning educational program on Nurse' knowledge, Attitude, and Practice about Nurse's Role in Organ Donation Process.Methods: In this Experimental study, Through Random Assignment, 3 ICU Wards of Gheam Hospital of Mashhad university of medical science devoted to Context-based Learning (Intervention) and 6 Wards devoted to Workshop Group (Control). Then through the Stratified Random Sampling Allocation Method, Demandable Nurses That Determine based on Pilot Study Were Selected and Intervention Was Done on 60 ICU Nurses (each group, n=30(. The CBL Training was performed in 3 sessions, every session length 2 hours, and the Time Interval between Sessions was 1 week. In the workshop group, Intervention was performed in two stages, every stages length 3 hours and between two stages was last 1 week. Both groups before and 1 month after intervention complete the questionnaire of Assessing Nurse's Knowledge, Attitude and Practice about Nurse's Role in Organ Donation Process. Data Analysis was done by SPSS11.5 software and by using t-test, Paired test, Wilcoxon, Man-whinny, and Chi-Square.Results: Change Score of Knowledge in Context-Based Learning was (43/4± 13/1) greater Than Workshop Group (14/3± 4/0) that statistically was Significant (p<0/001). Also in Attitude Change Score in Context-Based Learning was (28/7 ± 21/2) greater Than the Workshop group (13/1± 8/7) which statistically was Significant (p<0/001). Furthermore, in Practice Change Score in Context-Based Learning was (73/6± 21/1) greater Than the Workshop group (23/3± 6/8) which statistically was Significant (p<0/001).Conclusion: Based on Results, the Context-Based Learning Method had more effect in increasing the average Level of Knowledge, Attitude, and Practice about the Nurse’s Role in the Organ Donation Process rather than the Workshop Method. It is therefore suggested to utilize Context-Based Learning Method for the education of Nurse's Role in Organ Donation Process.