bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pragmatisme, positivisme et vérification : Peirce critique de Comte
Authors: Girel Mathias 
Published: May 2021

L’article étudie la relation de Peirce à Comte, en partant des critiques formulées dans ses écrits de jeunesse. Son enjeu est double : il relève d’abord d’une question d’histoire de la philosophie étonnamment peu traitée, alors même que Peirce lit, commente et critique Comte. Le second enjeu est épistémologique et métaphysique : Peirce voit dans la théorie comtienne des hypothèses une position proche du pragmatisme qu’il développe, mais grevée de présupposés nominalistes qui la rendent finalement intenable, à moins que l’on n’en adopte une lecture « charitable ». La confrontation avec Comte semble alors être l’occasion privilégiée d’une explicitation de son propre pragmatisme.
Chrysippe, les possibles et l’éternel retour
Authors: D’Jeranian Olivier 
Published: May 2021

Chrysippe a élaboré une stratégie contre l’argument Dominateur de Diodore afin d’éviter le nécessitarisme impliqué par le rejet des possibilités contrefactuelles. Alexandre d’Aphrodise lui oppose sa doctrine du retour périodique (Sur les Premiers Analytiques d’Aristote 180, 28 – 181, 34). Son objection repose sur une conception numérique de l’identité des individus à travers les cycles. Chrysippe n’admettant que leur ressemblance sinon leur stricte identité qualitative, sa doctrine du retour autorise les possibilités contrefactuelles.
Les arts énergétiques dans le dialogue des paradigmes scientifiques : bilan d’étape des bénéfices des disciplines corps-esprit (Yoga, Tai-chi, Qi-gong)
Authors: Guyon Alice , Ravenet Jérôme , Midol Nancy 
Published: May 2021

La définition des pratiques des arts énergétiques indiens ou chinois se heurte à un double problème, taxinomique et axiologique. Elle est au cœur d’un dialogue des cultures scientifiques d’Orient et d’Occident qui permet de dépasser le « choc » des civilisations. Dans cet article, nous proposons un bilan d’étape sur les bienfaits de ces pratiques du point de vue des neurosciences et des sciences cognitives, qui pourrait contribuer à réconcilier le mécanisme et le vitalisme, aider à dépasser le dualisme de la matière et de l’esprit, l’opposition qualité/quantité, holisme/réductionnisme... Bref, à marier les paradigmes de la science occidentale et de la science orientale pour s’inscrire dans une perspective de sport durable.
L’exil questionne le féminin
Authors: Poret Eugénie 
Published: May 2021

Alors que la vie humaine se perpétue par la différence des sexes, les femmes portent seules le fruit de la procréation. Ce pouvoir du féminin suscite chez les géniteurs un besoin de domination qui peut aller jusqu’à la violence et au meurtre.	L’institution, au lieu que de représenter le tiers dans l’échange et la transmission, propose une séparation et une intervention médicalisée à la reproduction de l’espèce.
Mais que veulent donc la chèvre et la poule au pays de la Covid ?
Authors: Siraudeau Diane 
Published: May 2021

Ce conte écrit dans « l’enfermement » d’un foyer d’accueil médicalisé, au cœur de la crise sanitaire, a jailli comme une nécessité vitale de traduire les paradoxes éprouvants qui se vivaient au sein de ses murs. Si nous nous laissons rêver et traverser par tous ces personnages qui nous habitent et qui racontent « l’universel » de nos tempêtes intérieures, alors un espace de liberté et un champ infini de possibles pourront peut-être se déployer.
Development and Validation of the Safe Parenteral Medication Administration Self-Efficacy Scale
Authors: Karahan Okuroglu Gülten , Şahin Orak Nuray , Mamedov Filiz , Ecevit Alpar Şule 
Published: May 2021

Background:
This study aimed to develop a valid and reliable measurement instrument for determining the self-efficacy perceptions of nurses concerning safe medication practices.

Method:
The study was conducted at the hospital of a state university in Istanbul, Turkey, between August and December 2016. The sample consisted of 278 nurses.

Results:
The exploratory factor analysis indicated the scale had a single-factor structure that explained 47.92% of the total variance. The remaining 76 items had factor loads ranging from .50 to .87. The item-total correlations varied between .49 and .86, and Cronbach's alpha coefficient for the scale was .98.

Conclusion:

The results of the analysis show the items constituting the scale have validity and reliability criteria that can measure the self-efficacy of nurses related to parenteral medication administration.

[
J Contin Educ Nurs
. 2021;52(6):267–273.]
Nobody Wants to Talk About Dying: Facilitating End-of-Life Discussions
Authors: Barra Maryanne 
Published: May 2021

Background:
This educational study investigated the association between nursing staff and end-of-life discussions in an assisted living facility. Although mandated, these conversations often are deficient due to health care providers' limited knowledge on advance care documents.

Method:
All staff underwent end-of-life training to identify their own reservations that prevent involvement with advance directive completion, develop advance directive competency, recognize the ramifications when advance directives are not documented, and role-play to experience different character viewpoints.

Results:
The group discussions and interview data were summarized into four main themes: not qualified to broach the end-of-life documents; reluctance to get involved; right place, right time, and right words; and who wants to think about death? Eleven subthemes that detailed descriptions from each category also were identified.

Conclusion:

Staff acknowledged the value of in-service education to alleviate their uncertainty on the subject matter, gaining confidence, proficiency, and perspectives with end-of-life planning.

[
J Contin Educ Nurs
. 2021;52(6):287–293.]
L’Adaptation du Colomba de Prosper Mérimée par Germaine Dulac
Authors: Bonnot-Gallucci Valécien 
Published: May 2021

En 1938 Germaine Dulac, directrice des actualités Gaumont, entreprend, avec Marie-Anne Malleville, d’adapter Colomba, une nouvelle de Prosper Mérimée située en Corse. Ce projet mené jusqu’à la veille du tournage ne verra pas le jour. Cet article exploite le fonds Dulac de la Cinémathèque française, où se trouve une continuité dialoguée, un découpage technique et des synopsis dans un dossier intitulé « Rimbecco » (qui signifie l’appel à la vengeance), afin d’examiner la nature de ce projet qui, comme la Carmen de Feyder pour l’Andalousie, convoque un document littéraire afin d’évoquer l’actualité de la Corse. Le récit envisagé est, en effet, situé en 1938 : il s’agit de créer un scénario « moderne » adapté aux « mœurs actuelles de la Corse », trouver dans ses paysages et ses coutumes matière à narration. Ainsi la transcription des voix populaires, l’enregistrement des chants, des sons, des lieux de tournage sont-ils privilégiés dans une approche de nature documentaire. Par ailleurs, à l’encontre de la représentation misogyne de la femme fatale de Mérimée, Dulac réinvente une « Colomba 38 » (un des titres envisagés) qui est une figure féministe.
Un peu de Brésil à Newmarket : notes sur la circulation internationale des travailleurs de la filière équine
Authors: Adelman Miriam 
Published: May 2021

Cet article examine un contexte particulier de travail avec les chevaux permettant la conversion du « capital équin » issu de la culture rurale brésilienne en un ensemble de compétences réutilisables à l’étranger. Il rejoint d’autres études sur la mobilité de certains travailleurs contemporains, notamment dans le domaine du sport mondial. Les trajectoires singulières de personnes qui, grâce au cheval, cherchent à se stabiliser et à se réaliser apparaissent pertinentes pour les débats en cours sur la mondialisation de la vie sociale.
Herpes Simplex Virus Type 2 Glycoprotein D Inhibits NF-κB Activation by Interacting with p65
Authors: Li Chuntian , Zhang Mudan , Guan Xinmeng , Hu Huimin , Fu Ming , Liu Yalan , Hu Qinxue 
Published: May 2021

Abstract
NF-κB plays a crucial role in regulating cell proliferation, inflammation, apoptosis, and immune responses. HSV type 2 (HSV-2) is one of the most predominant sexually transmitted pathogens worldwide, and its infection increases the risk of HIV type 1 (HIV-1) acquisition and transmission. HSV-2 glycoprotein D (gD), highly homologous to HSV-1 gD, is essential for viral adhesion, fusion, entry, and spread. It is known that HSV-1 gD can bind herpesvirus entry mediator (HVEM) to trigger NF-κB activation and thereby facilitate viral replication at the early stage of infection. In this study, we found that purified HSV-2 gD triggered NF-κB activation at the early stage of infection, whereas ectopic expression of HSV-2 gD significantly downregulated TNF-α–induced NF-κB activity as well as TNF-α–induced IL-6 and IL-8 expression. Mechanistically, HSV-2 gD inhibited NF-κB, but not IFN-regulatory factor 3 (IRF3), activation and suppressed NF-κB activation mediated by overexpression of TNFR-associated factor 2 (TRAF2), IκB kinase α (IKKα), IKKβ, or p65. Coimmunoprecipitation and binding kinetic analyses demonstrated that HSV-2 gD directly bound to the NF-κB subunit p65 and abolished the nuclear translocation of p65 upon TNF-α stimulation. Mutational analyses further revealed that HSV-2 gD interacted with the region spanning aa 19–187 of p65. Findings in this study together demonstrate that HSV-2 gD interacts with p65 to regulate p65 subcellular localization and thereby prevents NF-κB–dependent gene expression, which may contribute to HSV-2 immune evasion and pathogenesis.
Cutting Edge: Distinct B Cell Repertoires Characterize Patients with Mild and Severe COVID-19
Authors: Hoehn Kenneth B. , Ramanathan Palaniappan , Unterman Avraham , Sumida Tomokazu S. , Asashima Hiromitsu , Hafler David A. , Kaminski Naftali , Dela Cruz Charles S. , Sealfon Stuart C. , Bukreyev Alexander , Kleinstein Steven H. 
Published: May 2021

Abstract
Protective immunity against COVID-19 likely depends on the production of SARS-CoV-2–specific plasma cells and memory B cells postinfection or postvaccination. Previous work has found that germinal center reactions are disrupted in severe COVID-19. This may adversely affect long-term immunity against reinfection. Consistent with an extrafollicular B cell response, patients with severe COVID-19 have elevated frequencies of clonally expanded, class-switched, unmutated plasmablasts. However, it is unclear whether B cell populations in individuals with mild COVID-19 are similarly skewed. In this study, we use single-cell RNA sequencing of B cells to show that in contrast to patients with severe COVID-19, subjects with mildly symptomatic COVID-19 have B cell repertoires enriched for clonally diverse, somatically hypermutated memory B cells ∼30 d after the onset of symptoms. This provides evidence that B cell responses are less disrupted in mild COVID-19 and result in the production of memory B cells.
Patterns and Predictors of Left Ventricular Hypertrophy in Nigerians with Chronic Kidney Disease
Authors: Kalu Okorie Kalu , Hart Onwukwe Chikezie , Ifeoma Chikezie Nkiru , Thaddeus Nwagbara Chukwudi , Kalu Offia , Ukachukwu Osuji Charles 
Published: May 2021

Background:
Chronic kidney disease (CKD) impacts hugely on cardiovascular morbidity and mortality. Nigerian data on patterns and predictors of left ventricular hypertrophy (LVH) in persons living with CKD are scarce. The objective of the study is to describe the patterns and predictors of LVH in Nigerians with CKD.

Methods:
Recruitment and clinical assessment of adult Nigerians with CKD were done using standard procedures. Statistical analysis was done using appropriate statistical software.

Results:
Fifty-seven participants were involved in this study. Concentric and eccentric LVH occurred in 50% and 25% of the predialysis CKD patients, respectively, while 24% and 36% of the maintenance dialysis CKD patients had concentric and eccentric LVH, respectively. LVH patterns in dialysis-naive individuals were not significantly different from LVH patterns in persons on dialysis. The significant predictors of LVH in study participants were proteinuria, anemia, hypoalbuminemia, estimated glomerular filtration rate <30 mL/1.73 m2/min, and hypertensive nephrosclerosis. High calcium-phosphate product was a significant predictor of LVH in only participants on dialysis.

Conclusion:
This study showed no significant difference in LVH patterns among predialysis and maintenance dialysis CKD patients. Indices of deteriorating renal function were significant predictors of LVH in both categories of CKD patients. Early screening and treatment of significant risk factors of LVH are required in reducing CVD burden among CKD patients.
Role of Interictal Arterial Spin Labeling Magnetic Resonance Perfusion in Mesial Temporal Lobe Epilepsy
Authors: Mittal Ashima , Singh Dhanota Devinder Pal , Saggar Kavita , Singh Gagandeep , Ahluwalia Archana 
Published: May 2021

Context:
Electrophysiological and hemodynamic data can be integrated to accurately identify the generators of abnormal electrical activity in drug-resistant focal epilepsy. Arterial Spin Labeling (ASL), a magnetic resonance imaging (MRI) technique for quantitative noninvasive measurement of cerebral blood flow (CBF), can provide a direct measure of variations in cerebral perfusion associated with the epileptogenic zone.

Aims:
1. To evaluate usefulness of ASL for detecting interictal temporal hypoperfusion to localize the epileptogenic zone in patients of drug resistant mesial temporal lobe epilepsy (MTLE). 2. Correlation of localization of epileptogenic zone on ASL MR perfusion with structural MRI and EEG.

Methods and Materials:
30 patients with MTLE and10 age and gender matched normal controls were studied. All patients underwent ictal video EEG monitoring non-invasively, MR imaging with epilepsy protocol and pseudocontinuous ASL (PCASL) perfusion study. Relative CBF (rCBF) values in bilateral mesial temporal lobes were measured utilizing quantitative analysis of perfusion images. A perfusion asymmetry index (AI) was calculated for each region.

Results:
In patients, ipsilateral mesial temporal rCBF was significantly decreased compared with contralateral mesial temporal rCBF (p = 0.021). Mesial temporal blood flow was more asymmetric in patients than in normal control participants (p = 0.000). Clear perfusion asymmetry on PCASL-MRI was identified despite normal structural-MRI in 5 cases, agreeing with EEG laterality.

Conclusions:
Pseudo-continuous ASL offers a promising approach to detect interictal hypoperfusion in TLE and as a clinical alternative to SPECT and PET due to non-invasiveness and easy accessibility. Incorporation of ASL into routine pre-surgical evaluation protocols can help to localize epileptogenic zone in surgical candidates.
Analysis of differentially expressed genes induced by drought stress in tef (Eragrostistef) root
Authors: Degu Hewan Demissie 
Published: May 2021

Drought stress is one of the major abiotic stresses which induces root growth in tef. Molecular mechanisms underlying the elongation of roots under drought stress are not known. Therefore, we aimed to study the tef root system to uncover the expression profiles for drought stress using Agilent gene chip of rice. One hundred seventy-five expressed genes were found to be differentially expressed after eight days of drought stress with Eragrostis tef- resistant genotype, Kaye Murri. The drought-responsive genes were isolated and classified into nine categories according to the functional roles in plant metabolic pathways, such as defense, signal transduction, cell wall fortification, oxidative stress, photosynthesis, development, cell maintenance, RNA binding, and unknown functions. The profiles of tef root genes, responsive to drought stress shared common identities with other expression profiles known to be elicited by diverse stresses, including pathogenesis, abiotic stress, and wounding. Well-known drought-related transcription factor-like, WRKY and bHLH were up-regulated. Cell transport-related regulators such as potassium transporter 22-like, auxin transporter-like protein 1, and wall-associated receptor kinase were also involved in the expression profile of tef root under drought stress. Their expression had enhanced the drought-responsive genes, which, have a direct role to maintain root growth under drought stress.
Key words: Drought, Genome, Microarray, Root, Tef
SDS-Page characterization of some elite cowpea (Vigna unguiculata L. Walp) varieties
Authors: Oladejo A.S. , Bolaji A.O. , Obisesan I.O. , Omitogun O.G. 
Published: May 2021

The shortcomings of genotype x environment interaction necessitated the use of molecular methods in characterizing many plant species and in determining their phylogenetic relationships. In this study, some selected cowpea lines (27 varieties) from Obafemi Awolowo University, Ile – Ife, the Institute of Agricultural Research (IAR), Samaru, Kaduna and Genetic Resource Centre, IITA, Ibadan were characterized using sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) profiling. The protein banding profiles of the 27 cowpea varieties were scored and subjected to cluster analysis using Ward's minimum-variance method (WMVM) for dendrogram grouping. The dendrogram generated from the SDS-PAGE profiles grouped the varieties into seven clusters at 52% similarity coefficient. Hence, the biochemical characterization revealed more precise discrimination among the 27 cowpea varieties studied.
Keywords: Cowpea, electrophoretic banding profiles, dendrogram grouping, total proteins
STUDI DESKRIPTIF MUSIK TRADISIONAL LAGIA PADA KEBUDAYAAN NIAS DI SANGGAR MUSEUM PUSAKA NIAS KOTAMADYA GUNUNGSITOLI
Authors: Zebua Priska Eunike Putri 
Published: May 2021

ABSTRACT This study aims to determine the descriptive study of Lagia traditional music in Nias culture at the Museum Pusaka Nias. The approach tha the authors take is to use qualitative research methods. The work process carried out namely, observation, interviews, documentation, recording of activities, song transcript. This research was conducted by gathering information through field research to obtain results that are processed into original data. The results of the research show that Lagia is a single-stringed musical instrument made from salak roots, with a resonator made from sugar palm sticks, strings handles made of palm sugar pieces, strings made of tutura (rattan) and bow made of wood that has supple properties liek bamboo which are classified into the Chordophone classification. The author determines the location in the Museum Pusaka Nias and interview figures who ubderstand and understand it in that field. Lagia musical instrumen is played by using a bow which firts strings and both bow strins must be smeared with water (in the old days using saliva).Keywords : Descriptive study, Traditional Music, Lagia
Pemilihan dan Perjanjian Bangsa Israel Sebagai Hamba Tuhan (Tinjauan Teologis – Diakronis Kitab Deutro Yesaya dan Implementasinya Untuk Kehidupan Kristen Saat Ini)
Authors: Sitorus Gideon Hasiholan 
Published: May 2021

AbstrakDalam terlaksananya rancangan penebusan guna keselamatan, Allah melakukan pemilihan berdasarkan kedaulatan-Nya. Maka disini pemilihan bertujuan untuk suatu penyelamatan yang meliputi seluruh sejarah manusia. Sebagai bagian dari sejarah itulah Allah melakukan pemilihan satu bangsa yaitu Bangsa Israel. Inilah yang menjadi dasar bagi penulis akan apa yang menjadi konsep dari pemilihan Bangsa Israel dan seperti apa bentuk perjanjian Allah kepada Bangsa Israel. Karena dalam pemilihan hadir perjanjian sebagai perealisasian dari tujuan pemilihan tersebut. Inilah yang menjadi fokus penulis dalam pemilihan dan perjanjian Allah terhadap Bangsa Israel, karena Perjanjian Lama berfokus pada umat Allah sebagai penerima penyataan-Nya.Kata kunci : pemilihan, perjanjian, Israel, hamba Tuhan, teologis, diakronis Abstract In the implementation of the redemption plan for salvation, God makes election based on His sovereignty. So here the election aims for a salvation which covers the whole of human history. It is as part of this history that God chose one nation, namely the nation of Israel. This is the basis for the author of what the concept of the election of the Israelites will be and what God's covenant of Israel will look like. Because in the election there was an agreement as the realization of the election objective. This is what the author focused on in God's election and covenant to the Nation of Israel, because the Old Testament focuses on God's people as recipients of His revelation.Keywords: election, covenant, Israel, servant of God, theological, diachronic
Sampai Maut Memisahkan kita ? (Tafsir Matius 19:3-12 Diperhadapkan dengan Keberpihakan Gereja Terhadap Istri Korban KDRT)
Authors: Sirait Pdt Paulina Herlina Norayanti 
Published: May 2021

Till Death do us part?(Interpretation of Matthew 19:3-12 Faced with the Partisanship of the Church Against the Wife of the Victim of domestic violence)ABSTRACT Actually, the happy marriage of the coveted all pairs when beginning a commitment to bind themselves in marriage, accompanied by a promise to be loyal to live together in all situations: hard – fun, sick – healthy, poor – rich, until the end of life. But in fact, problems in the marriage are increasingly complex. The problems of the household that is increasingly complicated solved, contribute to the cause of the high divorce rate.HKBP as a protestant church in Southeast Asia uphold the integrity of the marriage of the citizens of his congregation, and impose strict regulations against the case of divorce, founded on the Word of God in the Bible: What God has joined together, let not man put asunder, except for sexual immorality (Matthew 19:6, 9). The problem is, there are certain cases in marriage not because of adultery, but has led to the loss of the existence of the marriage, such as acts of domestic violence that occur repeatedly and chronically, but not applicable as an excuse to allow the occurrence of divorce.This Paper assesses the return of Matthew 19:3-12 for the divorce, which faced up to the alignments of the church against victims of domestic VIOLENCE. With the interpretation of the more comprehensive, the church will bring news of liberation for women oppressed in a marital situation which is difficult.TAGS: Marriage, Divorce, domestic Violence, HKBP
Social & Behavioural Problems among School Going Adolescents of Garhwal region of Uttarakhand
Authors: Prachi Kothari  , Srivastava Ashok K , Neha Sharma  
Published: May 2021

Background: Mental health disorder is a major cause of impairment in youth aged between 9 to 17 years as one in every fifth youth has a mental disorder. In India, the prevalence of mental problems among adolescents is 14.3%. Objective: To find out the proportion of social and behavioural problems among adolescents and their association with the sociodemographic factors. Methods: A cross-sectional study was carried out among 150 school going adolescents (11-17years). All the study participants were recruited through non-probability sampling technique. Data was collected through Google Forms. For assessing the social and behavioural problems, Strength and Difficulty questionnaire (SDQ) was used. Result: There were 76 (50.7%) males and 74 (49.3%) females in this study. 16% of school going children were categorized as “abnormal”, 12% as borderline and 72.% as normal for social and behavioural problems based on scores of SDQ. The findings have implications that gender do play a role in affecting mental health status.Conclusions: Mental health problems are one of the most common and highly prevalent disorders among adolescents in India. For addressing psycho-social problems among adolescents there is a dire need of counsellors. Training of parents as well as teachers should be conducted for timely intervention.