bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strontium-90 brachytherapy following intralesional triamcinolone and 5-fluorouracil injections for keloid treatment: A randomized controlled trial
Authors: Deng Ke , Xiao Haitao , Liu Xiaoxue , Ogawa Rei , Xu Xuewen , Liu Yong 
Published: March 2021

Background
Keloid disease is hard to fully eradicate. Recurrence and other unsatisfactory results were found in many patients. No current therapeutic modality has been determined to be most effective for treating keloid scars. Intralesional corticosteroid injections is most commonly recommended for primary management of small and young keloids as well as hypertrophic scars. However, it’s difficult for patients to adhere to long-term triamcinolone acetonide injection therapy because of the pain, inconvenience or complications including hormonal imbalance or irregular menstruation.

Objective
We aimed to determine whether and how Strontium-90 brachytherapy as an adjuvant radiation could affect keloid recurrence after intralesional triamcinolone and 5-fluorouracil injections.

Methods
We included keloid patients from March 2019 to September 2019 and randomly allocated them to two groups after 3 intralesional triamcinolone and 5-fluorouracil injections at 3 weeks interval. The experimental group received Strontium-90 brachytherapy at a total dose of 15-20Gy, while the control group didn’t receive any adjuvant treatment. We performed both Vancouver Scar Scale scoring and Color Doppler ultrasound examination to monitor and evaluate lesions regularly. A one-year follow-up was completed for each patient.

Results
31 patients who had 42 keloids in total were recruited. We found intralesional triamcinolone and 5-fluorouracil injections could effectively reduce the thickness and modify the hardness of small and young keloids. Strontium-90 brachytherapy reduced the one-year recurrence rate from 85.7 percent to 44.4 percent after 3 intralesional triamcinolone and 5-fluorouracil injections. The lesions’ thickness or elasticity was not affected by Strontium-90 brachytherapy.

Conclusion
Strontium-90 brachytherapy as an adjuvant radiation could effectively reduce small sized keloids recurrence after intralesional triamcinolone and 5-fluorouracil injections. It worked by enhancing the lesions’ stability post-injection.

Trial registration
The clinical trial registration number: ChiCTR2000030141.
Name of trial registry: Chinese Clinical Trial Registry (http://www.chictr.org.cn/)
Effect of acute alcohol intoxication on mortality, coagulation, and fibrinolysis in trauma patients
Authors: Wang Il-Jae , Bae Byung-Kwan , Cho Young Mo , Cho Suck Ju , Yeom Seok-Ran , Lee Sang-Bong , Chun Mose , Kim Hyerim , Kim Hyung-Hoi , Lee Sun Min , Huh Up , Moon Soo Young 
Published: March 2021

Background
The effect of alcohol on the outcome and fibrinolysis phenotype in trauma patients remains unclear. Hence, we performed this study to determine whether alcohol is a risk factor for mortality and fibrinolysis shutdown in trauma patients.

Materials and methods
A total of 686 patients who presented to our trauma center and underwent rotational thromboelastometry were included in the study. The primary outcome was in-hospital mortality. Logistic regression analysis was performed to determine whether alcohol was an independent risk factor for in-hospital mortality and fibrinolysis shutdown.

Results
The rate of in-hospital mortality was 13.8% and blood alcohol was detected in 27.7% of the patients among our study population. The patients in the alcohol-positive group had higher mortality rate, higher clotting time, and lower maximum lysis, more fibrinolysis shutdown, and hyperfibrinolysis than those in the alcohol-negative group. In logistic regression analysis, blood alcohol was independently associated with in-hospital mortality (odds ratio [OR] 2.578; 95% confidence interval [CI], 1.550–4.288) and fibrinolysis shutdown (OR 1.883 [95% CI, 1.286–2.758]). Within the fibrinolysis shutdown group, blood alcohol was an independent predictor of mortality (OR 2.168 [95% CI, 1.030–4.562]).

Conclusions
Alcohol is an independent risk factor for mortality and fibrinolysis shutdown in trauma patients. Further, alcohol is an independent risk factor for mortality among patients who experienced fibrinolysis shutdown.
Temperature and Moisture Dependence of the Specific Heat of High Performance Concrete
Authors: Toman J. , Černý R. 
Published: March 2021

The specific heat of two types of high performance concrete was measured in the temperature range from 20 °C to 1000 °C and in the moisture range from dry material to saturation water content. A nonadiabatic method was chosen instead of classical adiabatic treatments in order to meet the requirements following from the large representative elementary volume of the materials. The measured results reveal a significant temperature effect on the specific heat value. The influence of moisture is less important than the influence of temperature, but is also not negligible.
Study of Pumping Capacity of Pitched Blade Impellers
Authors: Fořt I. , Jirout T. , Sperling R. , Jambere S. , Rieger F. 
Published: March 2021

A study was made of the pumping capacity of pitched blade impellers in a cylindrical pilot plant vessel with four standard radial baffles at the wall under a turbulent regime of flow. The pumping capacity was calculated from the radial profile of the axial flow, under the assumption of axial symmetry of the discharge flow. The mean velocity was measured using laser Doppler anemometry in a transparent vessel of diameter T = 400 mm, provided with a standard dished bottom. Three and six blade pitched blade impellers (the pitch angle varied within the interval a Îá24°; 45°ń) of impeller/vessel diameter ratio D/T = 0.36, as well as a three blade pitched blade impeller with folded blades of the same diameter, were tested. The calculated results were compared with the results of experiments mentioned in the literature, above all in cylindrical vessels with a flat bottom. Both arrangements of the agitated system were described by the impeller energetic efficiency, i.e, a criterion including in dimensionless form both the impeller energy consumption (impeller power input) and the impeller pumping effect (impeller pumping capacity). It follows from the results obtained with various geometrical configurations that the energetic efficiency of pitched blade impellers is significantly lower for configurations suitable for mixing solid-liquid suspensions (low impeller off bottom clearances) than for blending miscible liquids in mixing (higher impeller off bottom clearances).
Reliability of Concrete Elements Designed for Alternative Load Combinations Provided in Eurocodes
Authors: Holický M. , Marková J. 
Published: March 2021

The basic European standard for design of buildings and other engineering works, EN 1990 "Basis of structural design", provides alternative design procedures, for which national choice is allowed. One of the most important questions concerns three fundamental combinations of actions for persistent and transient design situations in the Ultimate limit states. Simple examples of reinforced concrete elements show, that the alternative load combinations may lead to considerably different reliability levels. Probabilistic methods of structural reliability theory are used to identify characteristic features of each combination and to formulate recommendations. However, further calibration studies are urgently needed in order to prepare National annexes to EN 1990 on time.
Die Design for Near-Net Shape Forging
Authors: Čermák J. , Gráf G. 
Published: March 2021

This paper discusses the use of conventional forging equipment for the manufacture of precise forging without flash. An analysis is presented of the factors influencing the forging process and the conditions for establishing this technique in a forge based on practical experience at the SKODA Auto forge. The main problem is usually the excess volume of billet material. Three basic forms of die design for overload protection are illustrated and discussed.
Pumping Capacity of Pitched Blade Impellers in a Tall Vessel with a Draught Tube
Authors: Brož J. , Fořt I. , Sperling R. , Jambere S. , Heiser M. , Rieger F. 
Published: March 2021

A study was made of the pumping capacity of pitched blade impellers (two, three, four, five and six blade pitched blade impellers with pitch angles α = 35° and 45°) coaxially located in a cylindrical pilot plant vessel with cylindrical draught tube provided with a standard dished bottom. The draught tube was equipped with four equally spaced radial baffles above the impeller pumping liquid upwards towards the liquid surface. In all investigated cases the liquid aspect ratio H/T = 1.2 - 1.5, the draught tube / vessel diameter ratios DT /T = 0.2 and 0.4 and the impeller / draught tube diameter ratio D/DT = 0.875. The pumping capacity of the impeller was calculated from the radial profile of the axial component of the mean velocity in the draught tube below the impeller at such an axial distance from the impeller that the rotor does not affect the vorticity of the flow. The mean velocity was measured using a laser Doppler anemometer with forward scatter mode in a transparent draught tube and a transparent vessel of diameter T = 400 mm. Two series of experiments were performed, both of them under a turbulent regime of flow of the agitated liquid. First, the optimum height of the dished bottom was sought, and then the dependences of the dimensionless flow rate criterion and the impeller power number on the number of impeller blades were determined for both pitch angles tested under conditions of optimum ratio HT /DT. It follows from the results of the experiments that the optimum ratio HT /DT = 0.25 when the cross sectional areas of the horizontal flow around the bottom and the vertical inflow to the draught tube are the same. For all the tested pitched blade impellers the impeller power number when α = 45° exceeds the value of this quantity when pitch angle α = 35°, while the flow rate number when α = 35° exceeds this quantity when α = 45°. On the other hand, the absolute values of the impeller power number when the draught tube was introduced correspond fairly well to the dimensionless impeller power input measured in a system without a draught tube. However, the absolute values of the flow rate number found in the former system are significantly lower than the dimensionless impeller pumping capacity determined in the latter system. The hydraulic efficiency of pitched blade impellers N3Qp/Po for the investigated geometry of the agitated systems does not depend on the number of impeller blades, but it is significantly lower than the quantity determined in an agitated system with a dished bottom but without the draught tube.
KBE Application for the Design and Manufacture of HSM Fixtures
Authors: Ríos J. , Jiménez J. V. , Pérez J. , Vizán A. , Menéndez J. L. , Más F. 
Published: March 2021

The design of machining fixtures for aeronautical parts is strongly based in the knowledge of the fixture designer, and it comprises certain repetitive tasks. An analysis of the design process allows us to state its suitability for developing Knowledge Based Engineering (KBE) applications in order to capture the knowledge, and to systematize and automate the designs.This work justifies the importance of fixtures for High Speed Milling (HSM), and explains the development of a KBE application to automate the design and manufacturing of such elements. The application is the outcome of a project carried out in collaboration with the company EADS.In the development process, a specific methodology was used in order to represent the knowledge in a semi-structured way and to document the information needed to define the system. The developed KBE application is independent of the parts design system. This makes it necessary to use an interface to input the part geometry into the KBE application, where it is analyzed in order to extract the relevant information for the fixture design process. The results obtained from the application come in three different ways: raw material drawings, fixture 3D solid models, and text files (Bill Of Materials – BOM, and Numerical Control – NC programs). All the results are exported to other applications for use in other tasks. The designer interacts with the application through an ad hoc interface, where he is asked to select or input some data and where the results are also visualized. The prototype KBE application has been carried out in the ICAD development environment and the main interface is with the CAD/CAM system CATIA V4.
Misja Kościoła — niezwykła zwykłość nauczania papieża Franciszka
Authors: Gardocki Dariusz 
Published: March 2021

With Pope Francis a new chapter has begun in the history of the Church. This newness refers to the new internal situation of the Church, new “signs of time”, and new challenges which the Church has to face. Through the symbolic gestures of his pastoral practice and the directions indicated in his homilies and encyclical letters Francis responds to these challenges in the spirit of the Gospel.
His whole pontificate is characterized by the profound desire to impart the newness and fresh- ness of the Gospel as well as what constitutes the core of its teaching. In this endeavor of returning to the sources, he sees the possibility of renewal of the Church. This entails a discernment of what constitutes the center and core of the Christian proclamation versus what is secondary, as well as how Jesus’ teaching has been distorted and deformed over the centuries. Francis speaks about the necessity of the apostolic and pastoral conversion of the Church. The Church has to undertake the “option for mission” and “apostolic dynamism”. She must go to the peripheries.
In his teaching Pope Francis imparts the traditional doctrine of the Church. But he does it in a new way, using new language, new gestures and a new way of life. Like his predecessors, he wants to serve the faith. He does not wish to change what constitutes the core of the Christian faith. But he wants the Church to grow in the understanding of the Gospel as well as in the discernment of the ways of the Spirit. Therefore, he emphasizes the constant need for the attitude of discernment. This is what he has learned above all from Ignatian spirituality and his pastoral experience: “the discernment of the spirits”.
Innovative techniques for the improvement of industrial noise sources identification by beamforming
Authors: Baldinelli Giorgio , Bianchi Francesco , Costarelli Danilo , D’Alessandro Francesco , Scrucca Flavio , Seracini Marco , Vinti Gianluca 
Published: March 2021

Abstract
An innovative technique based on beamforming is implemented, at the aim of detecting the distances from the observer and the relative positions among the noise sources themselves in multisource noise scenarios. By means of preliminary activities to assess the optical camera focal length and stereoscopic measurements followed by image processing, the geometric information in the source-microphone direction is retrieved, a parameter generally missed in classic beamforming applications. A corollary of the method consists of the possibility of obtaining also the distance among different noise sources which could be present in a multisource environment. A loss of precision is found when the effect of the high acoustic reflectivity ground interferes with the noise source.
The importance of changing urban scenery in the assessment of citizens’ soundscape perception. On the need for different time-related points of view
Authors: Manzano Jerónimo Vida , Pastor José Antonio Almagro , Quesada Rafael García 
Published: March 2021

Abstract
The city of Granada is experimenting a big urban transformation, attending national and international commitments on clean air, energy efficiency and savings linked to greenhouse gases reduction strategies and sustainable development action plans. This situation constitutes a good scenario for new noise control approaches that take into account the sound variable and citizens empowering in urban design, such as the soundscape assessment of urban territory. In this way, soundscape tools have been used in Granada as a complementary method for environmental noise characterisation where traditional noise control techniques are difficult to be carried out or give limited results. After 2016 strategic noise map and in the preparation of the new noise action plan, the city came across a great acoustic challenge in a new area located outskirts characterised by growing urbanisation, still under development, the greatest legal protection because of sensitive teaching and hospital buildings and the greatest noise exposure from nearby ring-way supporting heavy traffic flow. As quiet urban areas are not characterised by the absence of noise but for the presence of the right noise, this research intended to provide the local administration with results and proposals to transform this conflict area in a pleasant or quiet urban place. Main results came from important and significative differences in morning and evening characterisation, as great differences appear in soundscape assessment over the day and along the soundwalk path, indicating the importance of time and local issues to adequately characterised citizens perception to be considered by administration in the development of strategies and effective noise control actions.
Nasogastric- vs. percutaneous gastrostomy tube for prophylactic gastric decompression after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy
Authors: van Kooten Job P. , de Boer Nadine L. , Diepeveen Marjolein , Verhoef Cornelis , Burger Jacobus W. A. , Brandt-Kerkhof Alexandra R. M. , Madsen Eva V. E. 
Published: March 2021

Abstract

Objectives
Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is associated with postoperative gastroparesis and ileus. In 2015, our practice shifted from using percutaneous gastrostomy tubes (PGT), to nasogastric tubes (NGT) for prophylactic gastric decompression after CRS-HIPEC. This study aimed to compare these methods for length of stay (LOS) and associated complications.

Methods
Patients that underwent CRS-HIPEC for peritoneal metastases from colorectal cancer between 2014 and 2019 were included. Cases were grouped based on receiving NGT or PGT postoperatively. Multivariable linear regression determined the independent effect of decompression method on LOS, thereby adjusting for confounders.

Results
In total, 179 patients were included in the analyses. Median age was 64 years [IQR:54–71]. Altogether, 135 (75.4%) received a NGT and 44 (24.6%) received a PGT. Gastroparesis occurred significantly more often in the PGT group (18.2 vs. 7.4%, p=0.039). Median LOS was significantly shorter for patients with a NGT (15 [IQR:12–19] vs. 18.5 [IQR:17–25.5], p<0.001). PGT was independently associated with longer LOS in multivariable analysis (Beta=4.224 [95%CI 1.243–7.204]). There was no difference regarding aspiration, pneumonia and postoperative mortality between groups.

Conclusions
NGT should be preferred over PGT for gastric decompression after CRS-HIPEC as it is associated with fewer gastroparesis and shorter LOS.
Influence of technical parameters on the structure of annular axis braided preforms
Authors: Wang Xi , Zhang Guoli , Shi Xiaoping , Zhang Ce 
Published: March 2021

Abstract
A modified vertical braiding machine and closed annular axis mandrels with a special-shaped cross section were used to braid annular axis preforms under four different technical parameters. After measuring the braiding angles and yarn spacing of the braided preform in different areas of the mandrels, it was found that the braiding angle increased by 20.9% and the yarn spacing decreased by 19.8% when the speed of the yarn carrier was doubled. The braiding angle decreased by 31.1% and the yarn spacing increased by 28.6% when the rotation speed of the mandrels was doubled. The results show that the rotation speed of the mandrel has a slightly greater influence on the braiding angle and the yarn spacing. By using the modified braiding machine to braid the annular axis preforms, multi-layer continuous braided preforms can be achieved on compact equipment. And the structure of the annular axis braided preforms can be changed by changing the technical parameters.
Due enfances nel ms. D (Paris, BnF, fr. 1448): le Enfances Rainouart e l’Adoubement Vivien
Authors: Ghidoni Andrea 
Published: March 2021

Abstract
The 13th-century manuscript Paris, BnF, français 1448 (= D) contains a linking text between Enfances Vivien and Chevalerie Vivien. It can be divided into two nuclei, the first narrating the adventures of a young Rainouart and the second developing the dubbing of Vivien: in both cases, events of the biographies of two popular heroes only hinted at in other major poems, which a compiler decided to narrate extensively to fill the gap in the cycle of chansons on the geste Monglane. This paper, alongside the first critical edition of that text, offers a broad introduction on the literary and cultural features of these two stories (which can be classified as exemplars of the enfances sub-genre of medieval French epic).
It.usciere, fr.huissier, venez.schierazo‘nave da caricoʼ
Authors: Schweickard Wolfgang 
Published: March 2021

AbstractThe types It.uscieri/ Fr.huissierand Venet.schierazoare both derived from Ar.‛ušɛ̄rī‘cargo shipʼ. The term arrived in medieval times with the Crusaders in France and in the wake of the Arab conquests in Sicily and was adopted by the Genoese and Venetians in the course of their commercial activities. The second phase of its European history took place in the late 15th and 16th centuries, when the derivativeschierazoappeared in Venetian contexts.
Arbeitsraumsimulation für kollaborierende Roboter
Authors: Schmidt Malte , Partes Knut , Gorny Sven , Neiß-Theuerkauff Tobias , Wallhoff Frank 
Published: March 2021

Abstract
Kollaborierende Roboter (Cobots) können den Arbeitsraum mit Menschen teilen und dabei verschiedene Aufgaben ausführen. Das macht sie besonders für flexible Produktionssysteme interessant. Hierbei muss sichergestellt werden, dass die unterschiedlichen Bewegungsabläufe in allen Arbeitsumgebungen durchführbar sind. Mit einer Simulation der Roboterbewegungen ist es gelungen, die realen Arbeitsräume zu visualisieren und damit die Auslegung und Planung von Cobots in einer flexiblen Produktion zu verbessern.**)
Inventory Management während der COVID-19-Krise
Authors: Hafner Martin , Hagemeier Daniel , Letmathe Peter 
Published: March 2021

Abstract
In diesem Beitrag werden die Implikationen der COVID-19-Pandemie für das Lagerbestandsmanagement von produzierenden Unternehmen untersucht. Auf der Basis eines Inventory Dashboard werden fünf Handlungsempfehlungen für die Praxis abgeleitet, welche die reichweitenbezogenen Kennzahlen, das funktionsübergreifende Bestandscontrolling, Zielgrößenanpassungen, eine optimale Auslastung von Produktionskapazitäten sowie die Reaktionsgeschwindigkeit auf Nachfrageschocks adressieren.
Chance für mehr Ressourceneffizienz
Authors: Krommes Sandra , Tomaschko Florian 
Published: March 2021

Abstract
Die dynamische Wert- und Stoffstrommodellierung bildet die In- und Output-Ströme von Prozessen mittels Digitalisierungstechnologien ab. In einem aus fünf Schritten bestehenden methodischen Vorgehen kann der Einstieg in die Digitalisierung der Produktion für KMU mit bestehenden Anlagen- und Maschinenparks (Brownfield-Ansatz) gelingen: Ein digitaler Schatten ermöglicht ein echtzeit- und realdatenbasiertes Monitoring von Einzel- und Kleinserienfertigungen zur Steigerung der Ressourceneffizienz.*