bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perturbative Treatment of Three-Nucleon Force Contact Terms in Three-Nucleon Faddeev Equations
Authors: Witała H. , Golak J. , Skibiński R. , Topolnicki K. 
Published: May 2021

AbstractWe present a perturbative approach to solving the three-nucleon continuum Faddeev equation. This approach is particularly well suited to dealing with variable strengths of contact terms in a chiral three-nucleon force. We use examples of observables in the elastic nucleon-deuteron scattering as well as in the deuteron breakup reaction to demonstrate high precision of the proposed procedure and its capability to reproduce exact results. A significant reduction of computer time achieved by the perturbative approach in comparison to exact treatment makes this approach valuable for fine-tuning of the three-nucleon Hamiltonian parameters.
Pineal region tumours in the sitting position: how I do it
Authors: Sharma Priya , Abdul Mohd , Waraich Manprit , Samandouras George 
Published: May 2021

AbstractBackgroundPineal region tumours remain challenging neurosurgical pathologies.MethodsDetailed anatomical knowledge of the posterior incisural space and its variations is critical. An opaque arachnoidal membrane seals the internal cerebral and basal veins, leading to thalamic, basal ganglia, mesencephalic/pontine infarctions if injured. Medium-size tumours can be removed en-bloc with all traction/manipulation applied on the tumour side, virtually without contact of ependymal surfaces of the pulvinars or third ventricle. Sacrifice of the cerebello-mesencephalic fissure vein may be required.ConclusionsThe sitting position offers superior anatomical orientation and remains safe with experienced teams. Meticulous microsurgical techniques and detailed anatomical knowledge are likely to secure safe outcomes.
The connections of Locus Coeruleus with hypothalamus: potential involvement in Alzheimer’s disease
Authors: Giorgi Filippo Sean , Galgani Alessandro , Puglisi-Allegra Stefano , Busceti Carla Letizia , Fornai Francesco 
Published: May 2021

AbstractThe hypothalamus and Locus Coeruleus (LC) share a variety of functions, as both of them take part in the regulation of the sleep/wake cycle and in the modulation of autonomic and homeostatic activities. Such a functional interplay takes place due to the dense and complex anatomical connections linking the two brain structures. In Alzheimer’s disease (AD), the occurrence of endocrine, autonomic and sleep disturbances have been associated with the disruption of the hypothalamic network; at the same time, in this disease, the occurrence of LC degeneration is receiving growing attention for the potential roles it may have both from a pathophysiological and pathogenetic point of view. In this review, we summarize the current knowledge on the anatomical and functional connections between the LC and hypothalamus, to better understand whether the impairment of the former may be responsible for the pathological involvement of the latter, and whether the disruption of their interplay may concur to the pathophysiology of AD. Although only a few papers specifically explored this topic, intriguingly, some pre-clinical and post-mortem human studies showed that aberrant protein spreading and neuroinflammation may cause hypothalamus degeneration and that these pathological features may be linked to LC impairment. Moreover, experimental studies in rodents showed that LC plays a relevant role in modulating the hypothalamic sleep/wake cycle regulation or neuroendocrine and systemic hormones; in line with this, the degeneration of LC itself may partly explain the occurrence of hypothalamic-related symptoms in AD.
One-year performance of posterior narrow diameter implants in hyperglycemic and normo-glycemic patients—a pilot study
Authors: Friedmann Anton , Winkler Marianna , Diehl Daniel , Yildiz Mehmet Selim , Bilhan Hakan 
Published: May 2021

Abstract
Objectives
The aim of the study was to compare the performance of narrow diameter implants in patients with uncontrolled diabetes mellitus type 2 (T2DM) and normo-glycemic individuals during the first 12 months after implant loading.

Material and methods
In 16 T2DM patients with HbA1C > 6.5% (test group) and 16 normo-glycemic patients (HbA1C < 6.0%; control group), one to two narrow diameter tissue level implants were placed in the posterior maxilla or mandible. After 3-month lasting integration period, implants were loaded by fixed dentures. The clinical parameters probing depth (PD), bleeding on probing (BOP), attachment loss (CAL), recession and papilla bleeding index (PBI) were assessed manually at loading and after 12 months of function. The paired digital periapical radiographs were analyzed with regard to the change in marginal bone level (MBL) from baseline to 12 months’ control. The mean values calculated for both patient groups were statistically analyzed. The technical complications were recorded.

Results
The T2DM group accounted 13 patients due to 3 dropouts. The overall implant survival rate after 12 months was 100%. The differences in means for the clinical parameters and the MBL were statistically non-significant between the T2DM and normo-glycemic patients for the short period of loaded function reported here. No technical complications were recorded.

Conclusions
The study demonstrated an encouraging clinical outcome with narrow diameter implants in patients with uncontrolled T2DM compared to non-diabetics after 12 months post loading. For the short observation period, no biological and technical complications were reported regardless the glycemic status.

Clinical relevance
Patients with HbA1C > 6.5% may benefit from the treatment with narrow diameter implants by avoiding complex surgical interventions with augmentation procedures.

Trial registration
Clinicaltrials.gov: NCT04630691
Effects of acute alcohol consumption on neuronal activity and cerebral vasomotor response
Authors: Balogh Eszter , Árokszállási Tamás , Körtefái Katalin , Nagy Veronika Éva , Csiba László , Oláh László 
Published: April 2021

Abstract
Introduction
In the majority of European countries, driving after drinking small-moderate amount of alcohol is legal. Motivated by our previous studies on cerebral hemodynamics, we aimed to study whether a small-moderate blood alcohol content (BAC), at which driving is legal in some countries (0.8 g/L), influences the neuronal activity, neurovascular coupling, and cerebral vasoreactivity.

Methods
Analyses of pattern-reversal visual evoked potential (VEP) and transcranial Doppler (TCD) examinations were performed in thirty young healthy adults before and 30 min after alcohol consumption. Cerebral vasoreactivity was evaluated by breath holding test in both middle cerebral arteries. By using a visual cortex stimulation paradigm, visually evoked flow velocity response during reading was measured in both posterior cerebral arteries (PCA).

Results
The BAC was 0.82 g/L and 0.94 g/L 30 and 60 min after drinking alcohol, respectively. Latency of the VEP P100 wave increased after alcohol consumption. Resting absolute flow velocity values increased, whereas pulsatility indices in the PCA decreased after alcohol ingestion, indicating vasodilation of cerebral microvessels. Breath holding index and the visually evoked maximum relative flow velocity increase in the PCA and steepness of rise of the flow velocity curve were smaller after than before alcohol consumption.

Conclusion
BAC close to a legal value at which driving is allowed in some European countries inhibited the neuronal activity and resulted in dilation of cerebral arterioles. Cerebral vasodilation may explain the decrease of cerebral vasoreactivity and might contribute to the disturbance of visually evoked flow response after alcohol consumption.
A meta-algorithm for finding large k-plexes
Authors: Conte Alessio , Firmani Donatella , Patrignani Maurizio , Torlone Riccardo 
Published: May 2021

AbstractWe focus on the automatic detection of communities in large networks, a challenging problem in many disciplines (such as sociology, biology, and computer science). Humans tend to associate to form families, villages, and nations. Similarly, the elements of real-world networks naturally tend to form highly connected groups. A popular model to represent such structures is the clique, that is, a set of fully interconnected nodes. However, it has been observed that cliques are too strict to represent communities in practice. The k-plex relaxes the notion of clique, by allowing each node to miss up to k connections. Although k-plexes are more flexible than cliques, finding them is more challenging as their number is greater. In addition, most of them are small and not significant. In this paper we tackle the problem of finding only large k-plexes (i.e., comparable in size to the largest clique) and design a meta-algorithm that can be used on top of known enumeration algorithms to return only significant k-plexes in a fraction of the time. Our approach relies on: (1) methods for strongly reducing the search space and (2) decomposition techniques based on the efficient computation of maximal cliques. We demonstrate experimentally that known enumeration algorithms equipped with our approach can run orders of magnitude faster than full enumeration.
Genetic variability in oilseed rape DH line population developed from F1 hybrids obtained by crossing black-and yellow-seeded DH lines. I. yield and yield components
Authors: Szała Laurencja , Kaczmarek Zygmunt , Wójtowicz Marek , Sosnowska Katarzyna , Cegielska-Taras Teresa 
Published: May 2021

AbstractThe aims of this study were to estimate the diversity of doubled haploid population of winter oilseed rape (Brassica napus L.) in terms of yield, yield structure and seed colour, to determine the correlation between the studied traits and their heritability, and to select the best yellow-seeded genotypes. We studied 44 doubled haploids, obtained from F1 hybrids of a cross between a black-seeded DH H2-26 line and a yellow-seeded DH Z-114 line, as well as the parental forms. The greatest variation in DH line populations was observed for seed colour, seed yield and the number of pods per plant, while the smallest variability was obtained for thousand seed weight. Seed yield was positively correlated with the number of pods per plant and the number of seeds per pod, but negatively correlated with yellow seed colour. The broad-sense heritability coefficient was highest for seed colour and number of seeds per pod, and lowest for the number of pods per plant. When divided into 4 homogeneous groups according to seed colour, the genotypes differed significantly with respect to all the studied traits. A group of DH lines with black seed colour was characterized by the highest seed yield as well as highest thousand seed weight. The lowest yielding DH line group, that with yellow–brown seeds, had on average the highest number of seeds per pod and the lowest thousand seed weight. The best yellow-seeded genotypes were selected. Four yellow-seeded lines gave significantly higher yields than the yellow-seeded parental line.
The Function of Mounts in Free-Ranging Barbary Macaques (Macaca sylvanus)
Authors: Anzá Simone , Majolo Bonaventura , Amici Federica 
Published: May 2021

AbstractGenerally, nonreproductive sex is thought to act as “social grease,” facilitating peaceful coexistence between subjects that lack close genetic ties. However, specifc nonreproductive sexual behaviors may fulfill different functions. With this study, we aimed to test whether nonreproductive mounts in Barbary macaques are used to 1) assert dominance, 2) reinforce social relationships, and/or 3) solve conflicts. We analyzed nonreproductive mounts (N= 236) and postmount behavior in both aggressive and nonaggressive contexts, in 118 individuals belonging to two semi-free-ranging groups at La Montagne des Singes (France). As predicted by the dominance assertion hypothesis, the probability to be the mounter increased with rank difference, especially in aggressive contexts (increasing from 0.066 to 0.797 in nonaggressive contexts, and from 0.011 to 0.969 in aggressive contexts, when the rank difference was minimal vs. maximal). The strength of the social bond did not significantly predict the proportion of mounts across dyads in nonaggressive contexts, providing no support for the relationship reinforcement hypothesis. Finally, in support of the conflict resolution hypothesis, when individuals engaged in postconflict mounts, 1) the probability of being involved in further aggression decreased from 0.825 to 0.517, while 2) the probability of being involved in grooming interactions with each other increased from 0.119 to 0.606. The strength of the social bond between former opponents had no significant effect on grooming occurrence and agonistic behavior after postconflict mounts. Overall, our findings suggest that nonreproductive mounts in Barbary macaques have different functions that are not affected by the strength of the social bond.
The Thermal Diffusivity of Glass Sieves: II. Gas-saturated Frits
Authors: Hammerschmidt Ulf , Abid Muhammad 
Published: May 2021

AbstractThe thermal diffusivity of gas-saturated glass sieves (frits) of porosities between 20 % and 48 % is presented as measured at room temperature and ambient pressure. The saturants cover a range in thermal diffusivity from 20.63 × 10–6 m2⋅s−1 to 172 × 10–6 m2⋅s−1. The experiments were carried out using a transient hot-bridge instrument of an expanded uncertainty of 5 % to 10 %. It turned out that all measured thermal diffusivities of the gas-saturated frits (1) are smaller than that of the borosilicate glass the frits are made from and (2) are completely different from the thermal diffusivities of the liquid-saturated frits. Both these discrepancies can be attributed to characteristic properties of the matrix and not directly to the saturants. The first divergence results from thermal tortuosity that lengthens the pathway of heat through the matrix, whereas the second arises from dissolved He that enhances the transport of heat through the matrix.
Robot Speed Adaption in Multiple Trajectory Planning and Integration in a Simulation Tool for Human-Robot Interaction
Authors: Glogowski Paul , Böhmer Alexander , Hypki Alfred , Kuhlenkötter Bernd 
Published: April 2021

AbstractSpeed and separation monitoring (SSM) is one of the four permissible collaborative operations in human-robot interaction (HRI). At all times, it must be ensured that the speed-dependent separation distance is maintained. To guarantee this, the robot speed or the robot path can be adapted. In this paper, the robot speed adaption for multiple trajectories is implemented in an HRI simulation tool and tested in an application example. Thereby, numerous complex process situations, such as a temporary robot stop or obstacles in the collaborative workspace, can be simulated. The simulation tool enables a comprehensive simulation, analysis and optimisation of human and robot motions within the HRI, already in the planning phase.
Improvement of Adaptive Learning Service Recommendation Algorithm Based on Big Data
Authors: Yang Ya-zhi , Zhong Yong , Woźniak Marcin 
Published: May 2021

AbstractIn view of the problem that the traditional learning service recommendation does not fully consider the distinct differences between individuals, it is easy to lead to the contradiction between unchanging learning resources and learners’ personalized learning needs that are constantly improving, so an adaptive learning service recommendation improvement algorithm based on big data is proposed. Idea is based on adaptive learning platform and function modules. We consider the individual differences between students, to students as the center, collect students’ personalized learning demand data, and according to the data information to build student demand model. On the basis of using data mining methods for clustering recommendation service resources in learning, the adaptive recommend according to students’ individual need is proposed. The experimental results show that the adaptive learning service recommendation algorithm based on big data has high recommendation accuracy, coverage rate and recall rate, which is of great significance in the actual learning service recommendation.
Is there Consumer Risk-Pooling in the Open Economy? The Evidence Reconsidered
Authors: Minford Patrick , Ou Zhirong , Zhu Zheyi 
Published: May 2021

AbstractWe revisit the evidence on consumer risk-pooling and uncovered interest parity. Widely used single-equation tests are strongly biased against both. Using the full-model, Indirect Inference test, which is unbiased and has Goldilocks power according to Monte Carlo experiments, we find that both the risk-pooling hypothesis and its weaker UIP version are generally accepted as part of a full world DSGE model. The fact that the risk-pooling hypothesis, with its implication of strong cross-border consumer linkage, has passed this test with generally the highest p-value, suggests that it deserves serious attention from policy-makers looking for a relevant model with which to discuss international monetary and other business cycle policies.
Patient perceptions of anticoagulant treatment with dabigatran or a vitamin K antagonist for stroke prevention in atrial fibrillation according to region and age: an exploratory analysis from the RE-SONANCE study
Authors: Vinereanu Dragos , Napalkov Dmitry , Bergler-Klein Jutta , Benczur Bela , Ciernik Martin , Gotcheva Nina , Medvedchikov Alexey , Põder Pentti , Simić Dragan , Skride Andris , Tang Wenbo , Trusz-Gluza Maria , Vesely Jiří 
Published: April 2021

Abstract
Background
The oral anticoagulant dabigatran offers an effective alternative to vitamin K antagonists (VKAs) for stroke prevention in atrial fibrillation (AF), yet patient preference data are limited. The prospective observational RE-SONANCE study demonstrated that patients with AF, newly initiated on dabigatran, or switching to dabigatran from long-term VKA therapy, reported improved treatment convenience and satisfaction compared with VKA therapy. This pre-specified sub-study aimed to assess the impact of country and age on patients’ perceptions of dabigatran or VKA therapy in AF.

Methods
RE-SONANCE was an observational, prospective, multi-national study (NCT02684981) that assessed treatment satisfaction and convenience in patients switching from VKAs to dabigatran (Cohort A), or newly diagnosed with AF receiving dabigatran or VKAs (Cohort B), using the PACT-Q questionnaire. Pre-specified exploratory outcomes: variation in PACT-Q2 scores by country and age (< 65, 65 to < 75, ≥ 75 years) (both cohorts); variation in PACT-Q1 responses at baseline by country and age (Cohort B).

Results
Patients from 12 countries (Europe/Israel) were enrolled in Cohort A (n = 4103) or B (n = 5369). In Cohort A, mean (standard deviation) PACT-Q2 score increase was highest in Romania (convenience: 29.6 [23.6]) and Hungary (satisfaction: 26.0 [21.4]) (p < 0.001). In Cohort B, mean (standard error) increase in PACT-Q2 scores between dabigatran and VKAs was highest in Romania (visit 3: 29.0 [1.3]; 24.5 [0.9], p < 0.001). Mean PACT-Q2 score increase by age (all p < 0.001) was similar across ages. PACT-Q1 responses revealed lowest expectations of treatment success in Romania and greatest concerns about payment in Estonia, Latvia, and Romania, but were similar across ages.

Conclusions
Treatment satisfaction and convenience tended to favor dabigatran over VKAs. Regional differences in treatment expectations exist across Europe.

Trial and clinical registry
Trial registration number: ClinicalTrials.gov NCT02684981.
Trial registration date: February 18, 2016.
Bedtime smart device usage and accelerometer-measured sleep outcomes in children and adolescents
Authors: Lee Paul H. , Tse Andy C. Y. , Cheung Teris , Do C. W. , Szeto Grace P. Y. , So Billy C. L. , Lee Regina L. T. 
Published: April 2021

Abstract
Purpose
We analyzed the association between bedtime smart device usage habits and accelerometer-measured sleep outcomes (total sleeping time, sleep efficiency, and wake after sleep onset) in Hong Kong children and adolescents aged 8–14.

Methods
A total of 467 students in Hong Kong participated in this study from 2016 to 2017. They self-reported their bedtime smart device usage habits. The primary caregiver of each participant was also invited to complete a self-administered questionnaire about the family’s social-economic status and bedtime smart device usage habits. An ActiGraph GT3X accelerometer was used to assess participants’ 7-day sleep outcomes.

Results
The mean age of the participants was 10.3 (SD 1.9), and 54% were girls. Among the participants, 27% (n = 139) used a smart device before sleep, and 33% (n = 170) kept the smart device on before sleep. In total, 27% (n = 128) placed the smart device within reach before sleep, 23% (n = 107) would wake up when notifications were received, and 25% (n = 117) immediately checked the device after being awakened by a notification. Multiple regression controlling for age, sex, socio-economic status, and other confounders showed that those who woke up after receiving a notification had a statistically longer sleeping time (19.7 min, 95% CI: 0.3, 39.1, p = 0.046), lower sleep efficiency (− 0.71%, 95% CI − 1.40, − 0.02, p = 0.04), and a longer wake after sleep onset (2.6 min, 95% CI: 0.1, 5.1, p = 0.045) than those who did not. Nonetheless, all primary caregivers’ bedtime smart device habits were insignificantly associated with all sleep outcomes of their children.

Conclusion
Those who woke up after receiving smart device notifications had lower sleep efficiency and longer wake after sleep onset than those who did not, and they compensated for their sleep loss by lengthening their total sleep time.
Lithiation of white button mushrooms (Agaricus bisporus) using lithium-fortified substrate: effect of fortification levels on Li uptake and on other trace elements
Authors: Pankavec Sviatlana , Falandysz Jerzy , Komorowicz Izabela , Hanć Anetta , Barałkiewicz Danuta , Fernandes Alwyn R. 
Published: April 2021

AbstractHigh doses of lithium salts are used for the treatment or prevention of episodes of mania in bipolar disorder, but the medication is rapidly excreted and also shows side effects. Li may also be beneficial in people with mood disorders. Nutritionally, popular foods such as wild and cultivated mushrooms have low Li contents. This study evaluated the Li enrichment of whiteAgaricus bisporusmushrooms using Li2CO3solutions to fortify the commercial growing substrate at various concentrations from 1.0 to 500 mg kg−1dry weight (dw). Fortification of up to 100 mg kg−1dw resulted in a significant (p< 0.01) dose-dependent increase in the accumulation of Li in mushroom, but the highest fortification level was found to be detrimental to fruitification. The median values of Li in fortified mushrooms corresponded to the fortification levels, increasing from 0.49 to 17 mg kg−1dw relative to the background concentration of 0.056 mg kg−1dw (control substrate contained 0.10 mg kg−1dw). The potential for Li uptake in fruiting bodies was found to decrease at higher levels of fortification, with saturation occurring at 100 mg kg−1. Resulting lithiated mushrooms were up to 300-fold richer in Li content than specimens grown on control substrate. The fortification showed some effects on the uptake of other trace minerals, but concentrations of co-accumulated Ag, Al, As, Ba, Cd, Co, Cr, Cs, Cu, Hg, Mn, Ni, Pb, Rb, Sr, Tl, U, V and Zn were similar or lower than values reported in the literature for commercialA. bisporus. These lithiated mushrooms could be considered as a pro-medicinal alternative to treatments that use Li salts.Graphical abstract