bluuebunny/crossref_metadata_2025_split huggingface dataset:
A survey on the design space of end-user-oriented languages for specifying robotic missions
Authors: Dragule Swaib , Berger Thorsten , Menghi Claudio , Pelliccione Patrizio 
Published: February 2021

AbstractMobile robots are becoming increasingly important in society. Fulfilling complex missions in different contexts and environments, robots are promising instruments to support our everyday live. As such, the task of defining the robot’s mission is moving from professional developers and roboticists to the end-users. However, with the current state-of-the-art, defining missions is non-trivial and typically requires dedicated programming skills. Since end-users usually lack such skills, many commercial robots are nowadays equipped with environments and domain-specific languages tailored for end-users. As such, the software support for defining missions is becoming an increasingly relevant criterion when buying or choosing robots. Improving these environments and languages for specifying missions toward simplicity and flexibility is crucial. To this end, we need to improve our empirical understanding of the current state-of-the-art of such languages and their environments. In this paper, we contribute in this direction. We present a survey of 30 mission specification environments for mobile robots that come with a visual and end-user-oriented language. We explore the design space of these languages and their environments, identify their concepts, and organize them as features in a feature model. We believe that our results are valuable to practitioners and researchers designing the next generation of mission specification languages in the vibrant domain of mobile robots.
Framing of sustainable agricultural practices by the farming press and its effect on adoption
Authors: Rust Niki A. , Jarvis Rebecca M. , Reed Mark S. , Cooper Julia 
Published: February 2021

AbstractThere is growing political pressure for farmers to use more sustainable agricultural practices to protect people and the planet. The farming press could encourage farmers to adopt sustainable practices through its ability to manipulate discourse and spread awareness by changing the salience of issues or framing topics in specific ways. We sought to understand how the UK farming press framed sustainable agricultural practices and how the salience of these practices changed over time. We combined a media content analysis of the farming press alongside 60 qualitative interviews with farmers and agricultural advisors to understand whether the farming press influenced farmers to try more sustainable practices. Salience of sustainable agricultural practices grew between 2009 and 2020. Many of the practices studied were framed by the press around economic and agronomic aspects, and farmer respondents said the most common reasons for trying sustainable agricultural practices were for economic and agronomic reasons. The farming press tended to use more positive rather than negative tones when covering sustainable agricultural practices. Respondents used the farming press as a source of information, though many did not fully trust these outlets as they believed the farming press were mouthpieces for agribusinesses. Whilst a minority of farmers stated they were motivated to try a new sustainable agricultural practice after learning about it in the farming press, this was rare. Instead, the farming press was used by respondents to raise their awareness about wider agricultural topics. We reflect on the role and power given to agribusinesses by the farming press and what this means for agricultural sustainability.
Performance of a novel protease-activated fluorescent imaging system for intraoperative detection of residual breast cancer during breast conserving surgery
Authors: Lanahan Conor R. , Kelly Bridget N. , Gadd Michele A. , Specht Michelle C. , Brown Carson L. , Hughes Kevin S. , Tang Rong , Rai Upahvan , Brachtel Elena F. , Rice-Stitt Travis , Smith Barbara L. 
Published: February 2021

Abstract
Purpose
Safe breast cancer lumpectomies require microscopically clear margins. Real-time margin assessment options are limited, and 20–40% of lumpectomies have positive margins requiring re-excision. The LUM Imaging System previously showed excellent sensitivity and specificity for tumor detection during lumpectomy surgery. We explored its impact on surgical workflow and performance across patient and tumor types.

Methods
We performed IRB-approved, prospective, non-randomized studies in breast cancer lumpectomy procedures. The LUM Imaging System uses LUM015, a protease-activated fluorescent imaging agent that identifies residual tumor in the surgical cavity walls. Fluorescent cavity images were collected in real-time and analyzed using system software.

Results
Cavity and specimen images were obtained in 55 patients injected with LUM015 at 0.5 or 1.0 mg/kg and in 5 patients who did not receive LUM015. All tumor types were distinguished from normal tissue, with mean tumor:normal (T:N) signal ratios of 3.81–5.69. T:N ratios were 4.45 in non-dense and 4.00 in dense breasts (p = 0.59) and 3.52 in premenopausal and 4.59 in postmenopausal women (p = 0.19). Histopathology and tumor receptor testing were not affected by LUM015. Falsely positive readings were more likely when tumor was present < 2 mm from the adjacent specimen margin. LUM015 signal was stable in vivo at least 6.5 h post injection, and ex vivo at least 4 h post excision.

Conclusions
Intraoperative use of the LUM Imaging System detected all breast cancer subtypes with robust performance independent of menopausal status and breast density. There was no significant impact on histopathology or receptor evaluation.
shARe-IT: Ad hoc Remote Troubleshooting through Augmented Reality
Authors: Ludwig Thomas , Stickel Oliver , Tolmie Peter , Sellmer Malte 
Published: February 2021

Abstract10 years ago, Castellani et al. (Journal of Computer Supported Cooperative Work, vol. 18, no. 2–3, 2009, pp. 199–227, 2009) showed that using just an audio channel for remote troubleshooting can lead to a range of problems and already envisioned a future in which augmented reality (AR) could solve many of these issues. In the meantime, AR technologies have found their way into our everyday lives and using such technologies to support remote collaboration has been widely studied within the fields of Human-Computer Interaction and Computer-Supported Cooperative Work. In this paper, we contribute to this body of research by reporting on an extensive empirical study within a Fab Lab of troubleshooting and expertise sharing and the potential relevance of articulation work to their realization. Based on the findings of this study, we derived design challenges that led to an AR-based concept, implemented as a HoloLens application, called shARe-it. This application is designed to support remote troubleshooting and expertise sharing through different communication channels and AR-based interaction modalities. Early testing of the application revealed that novel interaction modalities such as AR-based markers and drawings play only a minor role in remote collaboration due to various limiting factors. Instead, the transmission of a shared view and especially arriving at a shared understanding of the situation as a prerequisite for articulation work continue to be the decisive factors in remote troubleshooting.
A novel methylated analogue of L-Mimosine exerts its therapeutic potency through ROS production and ceramide-induced apoptosis in malignant melanoma
Authors: Kyriakou Sotiris , Cheung William , Mantso Theodora , Mitsiogianni Melina , Anestopoulos Ioannis , Veuger Stephany , Trafalis Dimitris T. , Franco Rodrigo , Pappa Aglaia , Tetard David , Panayiotidis Mihalis I. 
Published: February 2021

SummaryMelanoma is an aggressive and highly metastatic type of skin cancer where the design of new therapies is of utmost importance for the clinical management of the disease. Thus, we have aimed to investigate the mode of action by which a novel methylated analogue of L-Mimosine (e.g., L-SK-4) exerts its therapeutic potency in an in vitro model of malignant melanoma. Cytotoxicity was assessed by the Alamar Blue assay, oxidative stress by commercially available kits, ROS generation, caspase 3/7 activation and mitochondrial membrane depolarisation by flow cytometry, expression of apoptosis-related proteins by western immunoblotting and profiling of lipid biosynthesis by a metabolomic approach. Overall, higher levels of ROS, sphingolipids and apoptosis were induced by L-SK-4 suggesting that the compound’s therapeutic potency is mediated through elevated ROS levels which promote the upregulation of sphingolipid (ceramide) biosynthesis thus leading to the activation of both extrinsic and intrinsic apoptosis, in an experimental model of malignant melanoma.
Modelling Perjury: Between Trust and Blame
Authors: Skoczeń Izabela 
Published: February 2021

AbstractI investigate: (1) to what extent do folk ascriptions of lying differ between casual and courtroom contexts? (2) to what extent does motive (reason) to lie influence ascriptions of trust, mental states, and lying judgments? (3) to what extent are lying judgments consistent with previous ascriptions of communicated content? Following the Supreme Court’s Bronston judgment, I expect: (1) averaged lying judgments to be similar in casual and courtroom contexts; (2) motive to lie to influence levels of trust, mental states ascriptions, and patterns of lying judgments; (3) retrospective judgments of lying, after being presented with the state of the world, to be inconsistent with previous judgments of communicated content: participants hold the protagonist responsible for content she did not communicate. I performed a survey experiment on the Qualtrics platform. Participants were recruited through Amazon Mechanical Turk (N = 630). I employed standard Likert scales and forced-choice questions. I found that: (1) average lying judgments are similar in casual and courtroom contexts; (2) motive to lie decreases trust ascription and increases lying judgment; (3) judgments of lying are inconsistent with previous judgments of communicated content: participants hold the protagonist responsible for content they did not communicate (effect size of the difference d = .69). Perjury ascriptions are inconsistent. The Supreme Court’s worries expressed in the Bronston judgment are well founded. This article helps reforming jury instructions in perjury cases.
Another way logic might be normative
Authors: Evershed J. W. 
Published: February 2021

AbstractIs logic normative for reasoning? In the wake of work by Gilbert Harman and John MacFarlane, this question has been reduced to: are there any adequate bridge principles which link logical facts to normative constraints on reasoning? Hitherto, defenders of the normativity of logic have exclusively focussed on identifying adequatevaliditybridge principles: principles linking validity facts—facts of the form$$\varGamma \models \varphi $$Γ⊧φ—to normative constraints on reasoning. This paper argues for two claims. First, for the time being at least, Harman’s challenge cannot be surmounted by articulating validity bridge principles. Second, Harman’s challenge can be met by articulatinginvaliditybridge principles: principles linking invalidity facts of the form$$\varGamma \not \models \psi $$Γ⊭ψto normative constraints on reasoning. In doing so, I provide a novel defence of the normativity of logic.
No evidence for flooding stress memory in saplings of eight hardwood floodplain forest species
Authors: Schindler Melanie , Schäfer Franziska , Donath Tobias W. , Ludewig Kristin 
Published: February 2021

AbstractAlluvial floodplain forests became rare in many parts of Europe, due to anthropogenic changes. Therefore, restoration of floodplain forests is important, but a difficult task because of the complex environmental conditions. The zonation of woody species in floodplains is mainly determined by hydrological conditions, not only within one year but also during the previous years. Tolerance to flooding can be regarded as a key factor for the successful establishment. We examined whether a previous flooding showed an increased flooding tolerance of saplings from eight woody floodplain forest species after a recurrent flooding under controlled common garden conditions at the research station Gießen-Leihgestern (Germany). This would indicate a stress memory towards flooding stress. The individuals of the experiment already experienced a partial flooding of three different durations (three, six or nine weeks) or no flooding in the previous year. After nine months of recovery, these fourteen-month-old saplings were again either exposed to a partial flooding of nine weeks or no flooding. We assessed foliar injury and growth in terms of plant height, number of leaves and stem diameter three weeks (short-term recovery) and nine months (medium-term recovery) after flooding. The saplings showed no increased tolerance to a recurrent flooding irrespective of the previous experienced flooding duration. Therefore, no immediate stress memory towards flooding stress could be observed. To recover after flooding seems to be the better option compared to forming a stress memory, which explained that most species showed a decreased foliar injury after medium-term compared to short-term recovery period.
Calcium aluminate cement as an alternative to ordinary Portland cement for the remediation of heavy metals contaminated soil: mechanisms and performance
Authors: Calgaro Loris , Contessi Silvia , Bonetto Alessandro , Badetti Elena , Ferrari Giorgio , Artioli Gilberto , Marcomini Antonio 
Published: February 2021

AbstractPurposeThis work deals with the application of a solidification/stabilization process with the aim to obtain safe and reusable granular materials from a polluted soil and to elucidate the mechanisms involved in the retention of several heavy metals.Materials and methodsThe High Performance Solidification/Stabilization (HPSS®) process was applied to the selected contaminated soil by using both ordinary Portland cement and calcium aluminate cement, as well as several binders prepared by combining these two types of cement in different proportions. Leaching and mechanical tests were carried out to evaluate the performances of the proposed binders in the pellets produced by the HPSS® process, while XRD analysis and SEM/EDX imaging were used to investigate the phase composition and internal microstructure of the treated samples.Result and discussionThe examination of the obtained granular materials revealed that the immobilization of Sb was mainly related to its inclusion within calcium silicate hydrates’ structure; the immobilization of Cr, Pb, Ni, Co, Zn and Tl was associated with the eluate pH and their incorporation within ettringite structure, while for Se, Cu, Ba and V, the main retention mechanism was physical encapsulation. In addition, the application of a wet conditioning process improved the materials’ performance, leading to granules always satisfying the Italian regulatory requirements for reuse.ConclusionsThe findings obtained in this study were useful to better elucidate the mechanisms involved in the retention of heavy metals by several binders, contributing to the development of sustainable management strategies for contaminated soils and sediments through their transformation into reusable materials.Graphical abstract
Logboat Repairs in Britain and Ireland: A New Typology
Authors: Holtzman Bob 
Published: February 2021

AbstractRepairs in British and Irish archeological logboats have been recorded and described by several authors, and the wide variety of repair methods present has been noted, but otherwise, repairs have received little analytical attention. This may be a result of three factors: (1) failure to recognize the significance of repair as social action; (2) the absence of a convenient source that consolidates repair data from all countries of the Atlantic Archipelago; and (3) the inadequacy of existing typologies of logboat repairs. Because they fail to recognize the distinctiveness of certain types of repairs and to organize repair methods into logical categories consistent with the data, existing typologies are of little help in comparing archeological examples or in analyzing repair methods for spatial or temporal distributions. This paper argues that logboat repairs can be socially significant; tabulates all known repairs in British and Irish logboats; describes the situations or events that make repairs necessary; and proposes a typology of repair based on general mechanical or engineering responses to logboat damage. It also presents findings of spatial and temporal distributions of some aspects of repairs.
Percutaneous cervical coblation as therapeutic technique in the treatment of algo-dysfunctional pain of discal herniation
Authors: Pandolfi Marco , Galli Federica , Borelli Anna , Gurgitano Martina , Liguori Alessandro , Carrafiello Gianpaolo 
Published: February 2021

Abstract
Objective
To confirm the validity of coblation nucleoplasty in reduction of cervical discogenic nature.

Study design
In a monocentric prospective clinical observational study recruiting 20 patients, treated with percutaneous coblation for cervical discogenic pain in 16 months in our hospital, we have clinically evaluated 18 patients. The pain was scored with the Visual Analogic Scale (VAS) in a pre-procedural questionary, 3/4 monthly follow-up from treatment and, finally, in a long-term follow-up 2 years after procedure.

Results
The mean pre-procedural VAS score was 7.9 ± 1.6 (95%—Confidence Interval 7.198–8.634), while the mean post-procedural score after 3–4 months has been 2.5 ± 3.1 (95%—Confidence Interval 1.089–3.965) and 2.5 ± 2.5 (95%—Confidence Interval 1.367–3.687) after 2 years. Among 18 patients, in the shortly post-treatment follow-up, nine had a complete pain relief, four had a > 50% VAS reduction, two hada < 50% VAS reduction, three did not have any variation of VAS; after 2 years, six patients had a total pain resolution, eight had a > 50% VAS reduction, two hada < 50% VAS reduction, two did not have any benefit. No peri- and post-procedural complication has been observed.

Conclusions
In a spite of a little sample, our results showed coblation as a valid therapeutic option to reduce cervical discogenic pain in medicine-refractory patients, as an alternative or a previous choice before a more invasive surgical treatment.
The need for reference machines when energy labelling electric household appliances that are tested to international standards
Authors: Schencking Lotta Theresa Florianne , Stamminger Rainer 
Published: February 2021

AbstractThere are over 80 countries in the world that currently use some kind of energy label for electric household appliances. In Europe, as an example, a lot of appliances are obliged to have an energy label when shown for sale, including online. Energy labels give relevant information to the consumers to help them make an environmentally beneficial choice when buying a new appliance. However, the desire for an energy efficient appliance does not outweigh the wish for good performance. Therefore, some energy labels provide information about the performance of the appliance based on international performance measurement standards (hereafter: “international standards”). Indeed, within the one appliance, increased performance can often mean increased energy consumption, so a balance between these parameters needs to be made by product designers and users. Unlike measurements that are traceable to Systeme Internationale units through metrological traceability chains, there is no natural reference data for performance measurements. Therefore, some international standards use a reference machine to relate their testing results to. The comparison of test and reference machine eliminates variances, for example, due to the auxiliary materials used and the influence of manual preparation or assessment methods. Three international standards that are currently using reference machines are examined closely in this paper. It is assessed how the reference machines and their testing results are treated, whether the reference machines are comparable with their corresponding test machines and if the use of a reference machine can be considered beneficial for the testing procedure. Additionally, three key questions are developed that will indicate whether 13 other international standards for electric household appliances could also benefit from using a reference machine. The paper concludes with six recommendations for standardisation groups and energy policymakers that will help with deciding whether a reference machine should be implemented.
A comprehensive review of ultralow-weight proppant technology
Authors: Feng Yong-Cun , Ma Cheng-Yun , Deng Jin-Gen , Li Xiao-Rong , Chu Ming-Ming , Hui Cheng , Luo Yu-Yang 
Published: February 2021

AbstractProppant plays a critical role in the exploitation of oil and gas, especially in the development of nonconventional oil and gas resources. Proppants are small spheres that have adequate strength to withstand high closure stresses to keep cracks open; therefore, hydrocarbon flows smoothly into the wellbore. However, traditional proppants are prone to settling in hydraulic fracturing operations, which seriously affects the operation effect. To this end, ultralow-weight proppants have been extensively employed in the petroleum industry. One of the widespread forms of ultralow-weight proppant application in the oil and gas industry is related to light density. Ultralow-weight proppants will provide substantial flow paths with a considerably high propped surface area and remarkably reduce fine generation and scaling. This paper presents a comprehensive review of over 50 papers published in the past several decades on ultralow-weight proppants. The purpose of this study is to provide an overview of the current ultralow-weight proppant development status in raw materials, manufacturing process, performance characteristics, hydrophobic and lipophilic capabilities, and field application to promote the research of new ultralow-weight proppants. Lastly, this study analyzes the current challenges and emphasizes the development direction of fractured proppants.
Visual analytics of sensor movement data for cheetah behaviour analysis
Authors: Klein Karsten , Jaeger Sabrina , Melzheimer Jörg , Wachter Bettina , Hofer Heribert , Baltabayev Artur , Schreiber Falk 
Published: February 2021

Abstract
Current tracking technology such as GPS data loggers allows biologists to remotely collect large amounts of movement data for a large variety of species. Extending, and often replacing interpretation based on observation, the analysis of the collected data supports research on animal behaviour, on impact factors such as climate change and human intervention on the globe, as well as on conservation programs. However, this analysis is difficult, due to the nature of the research questions and the complexity of the data sets. It requires both automated analysis, for example, for the detection of behavioural patterns, and human inspection, for example, for interpretation, inclusion of previous knowledge, and for conclusions on future actions and decision making. For this analysis and inspection, the movement data needs to be put into the context of environmental data, which helps to interpret the behaviour. Thus, a major challenge is to design and develop methods and intuitive interfaces that integrate the data for analysis by biologists. We present a concept and implementation for the visual analysis of cheetah movement data in a web-based fashion that allows usage both in the field and in office environments.

Graphic abstract