bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Machine Learning Prediction Model of Respiratory Failure Within 48 Hours of Patient Admission for COVID-19: Model Development and Validation
Authors: Bolourani Siavash , Brenner Max , Wang Ping , McGinn Thomas , Hirsch Jamie S , Barnaby Douglas , Zanos Theodoros P ,   Northwell COVID-19 Research Consortium
Published: January 2021

Background
Predicting early respiratory failure due to COVID-19 can help triage patients to higher levels of care, allocate scarce resources, and reduce morbidity and mortality by appropriately monitoring and treating the patients at greatest risk for deterioration. Given the complexity of COVID-19, machine learning approaches may support clinical decision making for patients with this disease.

Objective
Our objective is to derive a machine learning model that predicts respiratory failure within 48 hours of admission based on data from the emergency department.

Methods
Data were collected from patients with COVID-19 who were admitted to Northwell Health acute care hospitals and were discharged, died, or spent a minimum of 48 hours in the hospital between March 1 and May 11, 2020. Of 11,525 patients, 933 (8.1%) were placed on invasive mechanical ventilation within 48 hours of admission. Variables used by the models included clinical and laboratory data commonly collected in the emergency department. We trained and validated three predictive models (two based on XGBoost and one that used logistic regression) using cross-hospital validation. We compared model performance among all three models as well as an established early warning score (Modified Early Warning Score) using receiver operating characteristic curves, precision-recall curves, and other metrics.

Results
The XGBoost model had the highest mean accuracy (0.919; area under the curve=0.77), outperforming the other two models as well as the Modified Early Warning Score. Important predictor variables included the type of oxygen delivery used in the emergency department, patient age, Emergency Severity Index level, respiratory rate, serum lactate, and demographic characteristics.

Conclusions
The XGBoost model had high predictive accuracy, outperforming other early warning scores. The clinical plausibility and predictive ability of XGBoost suggest that the model could be used to predict 48-hour respiratory failure in admitted patients with COVID-19.
mHealth App for Pressure Ulcer Wound Assessment in Patients With Spinal Cord Injury: Clinical Validation Study
Authors: Do Khac Ariane , Jourdan Claire , Fazilleau Sylvain , Palayer Claire , Laffont Isabelle , Dupeyron Arnaud , Verdun Stéphane , Gelis Anthony 
Published: January 2021

Background
Clinical evaluation of a pressure ulcer is based on quantitative and qualitative evaluation. In clinical practice, acetate tracing is the standard technique used to measure wound surface area; however, it is difficult to use in daily practice (because of material availability, data storage issues, and time needed to calculate the surface area). Planimetry techniques developed with mobile health (mHealth) apps can be used to overcome these difficulties.

Objective
The goal of this study was to evaluate the metrological properties of a free-access mHealth app, called imitoMeasure, to assess pressure ulcers.

Methods
This was a noninterventional, validation study. We included patients with spinal cord injury presenting with a pressure ulcer, regardless of its stage or location. We performed wound measurements with a ruler, and we performed acetate tracing using a transparent dressing with a wound measurement grid. Wound evaluation via the mHealth app was conducted twice by the main investigator and also by a coinvestigator to determine validity, intrarater reproducibility, and interrater reproducibility. Bland-Altman plots and intraclass correlation coefficients were used to compute the minimal detectable change percentage.

Results
Overall, 61 different pressure ulcers were included. The validity, intrarater reproducibility, and interrater reproducibility of the mHealth app vs acetate tracing (considered the method of reference) were good, with intraclass correlation coefficients of 0.97 (95% CI 0.93-0.99), 0.99 (95% CI 0.98-0.99), and 0.98 (95% CI 0.96-0.99), respectively, and minimal detectable change percentages between 17% and 35%.

Conclusions
The imitoMeasure app had good validity and reproducibility. It could be an alternative to standard wound assessment methods. Further studies on larger and more diverse wounds are needed.

Trial Registration
ClinicalTrials.gov NCT04402398; http://clinicaltrials.gov/ct2/show/NCT04402398
Impacts of a one-shot training program for in-service teachers on the application of Task-based Language Teaching
Authors: Thi Nguyen Anh , Yen Phuong Hoang 
Published: January 2021

Tieng Anh:Task-based language teaching (TBLT) has been recently implemented as a potential language teaching method for language education in Vietnam. However, research into the training for teachers on the application of TBLT has remained scarce. This study, therefore, aims to examine how Vietnamese in-service teachers implement the insights from a one-shot training program on TBLT in their classroom-based teaching practices. Three in-service teachers at a university in Vietnam participated. Data were collected through a video-taped classroom observation activity. Findings indicate that the teachers on the whole were unable to transfer the theoretical knowledge of TBLT principles that they had built up during the training program into their actual teaching practices. In addition, the teachers failed to perform TBLT teaching roles throughout the lesson. Accordingly, this study suggests pedagogical implications and insights with regard to the issue of teacher training on TBLT in the context of language education in Vietnam.Tieng Viet:Phuong phap giang day co ten la "Task-based language teaching" (TBLT) duoc thuc thi gan day tai Viet Nam va duoc danh gia la mot phuong phap giang day ngon ngu rat tiem nang. Tuy nhien, den nay van khong co nhieu nghien cuu tim hieu ve hoat dong dao tao, tap huan giao vien de co the ung dung TBLT vao hoat dong giang day tren lop. Vi the, nghien cuu nay tap trung vao viec tim hieu muc do hieu qua cua hoat dong tap huan, cu the la hinh thuc tap huan ngan han (one-shot training) cho giao vien ve phuong phap TBLT, lieu giao vien co the ung dung duoc TBLT vao dieu kien giang day thuc te tren lop sau khoa tap huan hay khong. Ba giao vien giang day mon tieng Anh tai mot truong dai hoc o Viet Nam dong y tham gia vao nghien cuu. So lieu duoc thu thap thong qua hoat dong quay video ve hoat dong giang day cua giao vien tren lop. Ket qua nghien cuu cho thay nhin chung giao vien khong co kha nang thuc thi kien thuc TBLT (nguyen tac cot loi, vai tro giao vien) ma ho da duoc tap huan vao hoat dong giang day thuc te tren lop hoc cua minh. Tu ket qua do, nhom nghien cuu de xuat phuong huong, giai phap va ke hoach hanh dong cho hoat dong tap huan giao vien trong viec ung dung, thuc thi TBLT trong dieu kien giang day ngoai ngu tai Viet Nam.
Adsorption of chromium (VI) ion using adsorbent derived from lignin extracted coir pith
Authors: Thanh Luong Huynh Vu , Hanh Cao Luu Ngoc , Lan Tran Nguyen Phuong , Quyen Tran Thi Bich , Nam Ha Quoc 
Published: January 2021

In this study, coconut coir pith (cellulose-lignin compound) was first treated with water and sodium hydroxide solution to remove lignin and impurities, then lignin-extracted coir pith was calcined at 200°C for 6 h. The obtained absorbent was applied to remove Cr(IV) ions by using adsorption method. Some analytical methods such as thermal gravimetric analysis (TGA), Fourier Transform Infrared Spectroscopy (FT-IR), Brunauer–Emmett–Teller analysis (BET), X-ray powder diffraction analysis (XRD), pHpzc analysis, Boehm titration and potentiometric titration were employed to characterize structure, specific surface area, functional groups and surface charge of the absorbent. Adsorption results showed that 95.23% of Cr(IV) was removed from solution of 100 mg.L-1 by using certain amount of absorbent at pH 2.0 within 20 min at room temperature. Kinetics of Cr(VI) adsorption from aqueous solution on absorbent fit to Pseudo-second-order kinetic equation and adsorption isotherm of Cr(IV) followed to Freundlich model.
A qualitative evaluation of patient and healthcare provider knowledge, attitudes, and behavior for safety and use of pexidartinib
Authors: Salas Maribel , Julian Michele , Drogaris Leonidas , Islam Zahidul , Henderson Mackenzie , Stemhagen Annette , O'Donnell Natalie , Tu Nora 
Published: January 2021

Aim:
Pexidartinib is approved in the USA for the treatment of symptomatic tenosynovial giant cell tumor associated with severe morbidity or functional limitations and not amenable to improvement with surgery. Due to risk of serious liver injury, a survey of patient and healthcare provider (HCP) knowledge, attitudes, and behavior (KAB) of the risks was required.
Materials & methods:
Prior to KAB survey execution, structured telephone interviews with 12 patients and 12 HCPs were conducted.
Results:
The interviews revealed that patients had difficulty with the complexity and wordiness of some of the questions, while HCPs noted that some questions were repetitive with terminology that was not self-explanatory. Of the 15 questions initially in the patient survey, nine were modified for survey inclusion. For the HCP survey, 10 of 18 questions were modified.
Conclusion:
Qualitative research prior to KAB surveys is recommended to improve comprehension and data quality.
Nanosuspension as Promising and Potential Drug Delivery: A Review
Authors: Haranath Chinthaginjala  , Hindustan Abdul Ahad  , Pushpalatha Gutty Reddy  , Kalpana Kodi  , Sai Priyanka Manchikanti  , Devika Pasam  
Published: January 2021

In the last decade, nanosuspensions have gained considerable interest as a method for formulating poorly soluble drugs. Because of their cost-effectiveness and technological simplicity compared to liposomes and other colloidal drug carriers, nanoscale systems have recently received a lot of attention as a way of solving problems of solubility. Nanosuspensions are biphasic systems comprising of pure drug particles dispersed in an aqueous vehicle, stabilized by surface active agents. Fabrication of nanosuspension is simple and more advantageous than other approaches. Nanosuspension is a very finely single solid drug particle in an aqueous vessel, stabilized by surfactants for either oral or topical use or for parenteral and pulmonary administration, it can also be used for targeted drug delivery when incorporated in the ocular inserts and mucoadhesive hydrogels, with reduced particle size resulting in increased dissolution rate. This article covers the preparation of nanosuspension by bottom up technology, top down technology, melt emulsification, emulsification- solvent evaporation and supercritical fluid with their advantages and disadvantages, aspects of structure, classification and their drug delivery applications. Nanosuspension can be processed for the drugs which are of hydrophobic in nature quite easily employing stability enhancers, solvents that are of organic and additional ingredients including buffering agents, salts, PEG, osmotic agents and anti-freeze compounds.
USIA MENARCHE PEREMPUAN INDONESIA SEMAKIN MUDA: HASIL ANALISIS RISKESDAS 2010
Authors: Sudikno Sudikno , Sandjaja Sandjaja 
Published: January 2021

Abstract
Background: A downward trend in age at menarche (AAM) has been leveling-off in industrialized countries. However, downward trends were still observed in developing countries.
Objective: The aim was to verify secular trend of AAM among Indonesian women and its associated factors.
Methods: Data used were from Baseline Health Research (Riskesdas) 2010, a cross-sectional nationwide survey. Samples included were 79,026 women aged 10-59 years. History of menarche, socio-demographic variables, weight, height were taken. Descriptive and bivariate analysis were applied to measure proportion, central tendency measures.
Results: Among adolescent 10-19years, overall proportion of menarche was 78.6%, ranging from 42.8%, 96.2%, 99.6% at age 12, 15, 18 years respectively. The overall mean AAM was 12.96 years. AAM was significantly younger in urban than rural areas. BMI was significantly lower among adolescense not experienced menarche yet than experienced menarche. AAM was younger in urban areas, higher socio-economic status, and varied among seven regions.
Conclusions: Nutritional status was a significant factor associated with AAM. A downward trend in AAM was observed in Indonesian women.
Key words: menarche, secular trend, body mass index, Indonesian woman
Abstrak
Latar belakang: Tren penurunan usia pada menarche telah meningkat di negara-negara industri. Namun, tren penurunan masih diamati di negara-negara berkembang.
Tujuan: untuk memverifikasi tren sekuler usia menarche di kalangan perempuan Indonesia dan faktor-faktor terkaitnya.
Metode: Data yang digunakan berasal dari Riskesdas 2010, survei nasional dengan desain cross-sectional. Sampel yang dianalisis adalah 79.026 perempuan berumur 10-59 tahun. Variabel yang dikumpulkan meliputi: riwayat menarche, sosio-demografis, berat badan, tinggi badan. Analisis deskriptif dan bivariat digunakan untuk mengukur proporsi, ukuran kecenderungan sentral.
Hasil: Di antara remaja 10-19 tahun, proporsi keseluruhan menarche adalah 78,6 persen, mulai dari 42,8 persen, 96,2 persen, 99,6 persen pada masing-masing umur 12, 15, dan 18 tahun. Rata-rata keseluruhan usia menarche adalah 12,96 tahun. Usia menarche secara signifikan lebih muda di daerah perkotaan daripada pedesaan. IMT secara signifikan lebih rendah di antara remaja yang belum mengalami menarche dibandingkan dengan remaja yang sudah mengalami menarche. Usia menarche lebih muda di daerah perkotaan, status sosial ekonomi yang lebih tinggi, dan bervariasi di antara tujuh daerah.
Kesimpulan: Status gizi adalah faktor signifikan yang terkait dengan usia menarche. Terjadi Tren penurunan usia menarche pada perempuan di Indonesia.

Kata kunci: menarche, tren sekuler, indeks massa tubuh, perempuan Indonesia
Jogos de aprendizagem inventiva
Authors: Klein Gerson , Cristina V Biasuz Maria 
Published: January 2021

Esse artigo apresenta uma articulação do conceito ferramenta Caixa de Areia numa perspectiva de aprendizagem inventiva com base em Vigínia Kastrup; o embasamento dado por Duplesis sobre os processos de subjetivação da experiência de jogo; da classificação de tipos de atividade lúdica de Callois; das teorias de Game Design sobre jogos Caixa de Areia de Breslin e uma aproximação do tema com a práxis mediante as propostas do Game Design Racional e Design Atômico de McEntee, o artigo propõe uma discussão sobre pistas para a realização de jogos com fins de promover espaços para a problematização e a aprendizagem inventiva. Conclui-se que uma abordagem de planejamento de jogos inventivos, dentro da perspectiva da Caixa de Areia é compatível com o Game Design Racional e que a as aproximações de projeto baseadas na progressão projetada dentro das recomendações da teoria do fluxo de Csikszentmihalyi ocupam lugar privilegiado nessa discussão.
Gamification in the Educational Context: A Systematic Mapping of Literature with a Focus on the Evaluation of Gamification
Authors: Souto Reinheimer Wendel , Duarte Medina Roseclea 
Published: January 2021

Gamification has been a strategy widely used in the educational field to promote learning, engage and motivate students. Despite this, studies point to some issues related to the evaluation process in educational contexts. Thus, this work aims to identify the state of the art of evaluation in educational contexts. To this end, a systematic mapping of the literature was conducted. In total, 106 (one hundred and six) works were analyzed. As a result, a very heterogeneous scenario was found in the gamification evaluation process. Most authors carry out the evaluation of gamification in non-experimental studies; among the most used instruments are questionnaires. Regarding the observed metrics, most studies investigate metrics related to learning/performance, participation/interaction and metrics collected based on the opinion/perception of the participants.
Uso da tecnologia como ferramenta educativa sobre pré-natal odontológico: Uma revisão integrativa.
Authors: Andrade Tupinambá da Silva Bruna , Cardoso de Castro Berry Maria , Darlen Maia Katlin , Isabel de Castro de Souza Maria 
Published: January 2021

O objetivo deste estudo foi analisar evidências científicas que utilizaram diferentes tipos de metodologias e proposições sobre o uso de aplicativos móveis para gestantes, no contexto do pré-natal odontológico, através de uma revisão integrativa da literatura. De acordo com a metodologia PICO, a busca foi realizada entre os meses de outubro/2019 a abril/2020, nas bases de dados MedLine (via PubMed), Google Scholar e a biblioteca virtual SciELO. A pesquisa identificou um total de 484 artigos sendo 102 artigos provenientes da literatura branca e 382 artigos da literatura cinzenta. Dos 47 artigos incluídos no estudo, 33 (70%) artigos relataram o uso de aplicativos ou protótipos de aplicativos em sua metodologia e 14 artigos avaliaram somente a efetividade dos aplicativos, sem citar nenhum aplicativo específico. Em relação aos artigos que descreviam a usabilidade de aplicativos móveis no período do pré-natal, 70% concluiu que os aplicativos móveis avaliados foram capazes de desempenhar um papel importante na melhoria dos resultados em saúde e forneceram soluções adequadas para a melhoria na qualidade de atendimento no período do pré-natal. Concluiu-se através dessa revisão integrativa que existe uma escassez na literatura científica relacionada a aplicativos móveis para pré-natal odontológico sendo um campo amplo a ser explorado.
Ferramentas digitais para a avaliação do processo de aprendizagem: um mapeamento sistemático da literatura
Authors: Molon Jaqueline , Nicolao Mariano , Roberto Kieling Franco Sérgio 
Published: January 2021

Considerar a avaliação como fonte para a definição de ações pedagógicas direcionadas às necessidades dos estudantes exige a adoção de estratégias e ferramentas que possam tornar essa práxis possível. Neste artigo é apresentado um Mapeamento Sistemático da Literatura (MSL) realizado com o objetivo de identificar ferramentas digitais existentes para a avaliação da aprendizagem nas perspectivas formativa ou mediadora. A seleção dos artigos se deu por meio do Portal de Periódicos da Capes. A adoção de critérios de inclusão e exclusão resultou na seleção de 26 artigos para síntese e análise. Os resultados do MSL demonstram a existência de algumas ferramentas que avançam neste tema, no entanto se observa que a busca por recursos para a realização de uma avaliação mais individualizada e focada no desenvolvimento cognitivo dos estudantes ainda é um desafio que exige mais pesquisas na área.
Sala de aula invertida apoiada pela gestão do conhecimento
Authors: Fiorini Daniela , Carnevale de Almeida Iara , Fleig Dal Forno Letícia , Geller Marlise 
Published: January 2021

O distanciamento social imposto pelo Covid-19 fez com que as instituições de ensino passassem por um processo de ressignificação nos processos pedagógicos. Este estudo refina um planejamento de aulas baseado na Sala de Aula Invertida com Aprendizagem Baseada em Problemas e Orientação por meio de Projetos. Neste planejamento têm-se também práticas e ferramentas da Gestão do Conhecimento (GC) que podem ser vistas como estratégias que permitem, por exemplo, captar, estruturar e mapear conhecimentos como reutilizar conhecimento já estruturado. As adaptações feitas nesse planejamento permitem que ocorram momentos “antes” e “depois” das aulas remotas online. A metodologia adotada contempla pesquisa aplicada com abordagem qualitativa através de pesquisa descritiva de estudo de caso, após pesquisa bibliográfica exploratória e documental. Observou-se maior envolvimento, por parte dos alunos, para exporem os seus trabalhos e/ou dúvidas nas aulas remotas online. Isto proporcionou que as aulas fossem mais interessantes e participativas, o professor pode dar feedback sobre os trabalhos fazendo com que a “dúvida, erro ou acerto de um aluno” pudesse ser esclarecida e compreendida por todos. Espera-se com este estudo contribuir com as estratégias para promover a aprendizagem em períodos de isolamento social similares ao ocorrido com Covid-19.
Categorização de vídeos educacionais do Youtube por meio de comentários
Authors: Carlos Fonte Boa Carvalho Henrique , Grijó Pitangui Cristiano , Augusto Costa Trindade Eduardo , Pereira de Assis Luciana , Vivas Andrade Alessandro , Priscila Bicalho de Souza Dayane 
Published: January 2021

O Youtube ´e uma plataforma online que oferta Objetos de Aprendizagem sobre as mais diversas áreas do conhecimento. De maneira a facilitar a busca por conteúdos, o Youtube categoriza os seus vídeos em diversas classes. No entanto, já apontou-se que, de forma geral, a categorização dos vídeos não é relevante ou que as categorias estão erroneamente atribuídas aos vídeos. Este trabalho utiliza técnicas de Mineração de Texto com o objetivo de analisar os comentários dos vídeos e identificar se eles possuem potencial para serem utilizados para a categorização de vídeos educacionais. Resultados experimentais apontam que existem diferenças importantes nos vocabulários dos comentários dos vídeos educacionais e não educacionais.
PERSPECTIVAS DE LA EVALUACIÓN UNIVERSITARIA: UN RETO PARA LA EDUCACIÓN SUPERIOR Y LOS ORGANISMOS DE ACREDITACIÓN EN LA SOCIEDAD DEL CONOCIMIENTO
Authors: León-Londoño Guillermo 
Published: January 2021

ResumenEl artículo ofrece una perspectiva de la evaluación universitaria en donde la acreditación y la evaluación son dos dispositivos estratégicos que permiten orientar los desarrollos de la institución y de los programas, como instrumentos que la institución acoge y los utiliza según sus intereses y condiciones específicas.Sostieneque la educación no es responsabilidad exclusiva del Estado, de la sociedad o de la institución educativa, sino responsabilidad de todos, de manera compartida.Entendidos así los ejercicios de auto evaluación y evaluación externa y las relaciones que entre ellas se establecen se hace claro el principio de que "la evaluación es el ejercicio de la academia para examinar la academia" y que al Estado y a los entes externos sólo les es dado armarse de los criterios y mecanismos que aquella les proporciona.Establece los márgenes de accionar de la universidad y de los entes acreditadores, como la responsabilidad compartida y los límites en el accionar.Palabras claves: autoevaluación, acreditación, evaluación externa, educación superior, calidad. Abstract The article offers an overview of the university evaluation where the accreditation and evaluation are two strategic devices capable of guiding the development of the institution and programs, including instruments that the institution welcomes and uses them according to their interests and specific conditions. It argues that education is not the sole responsibility of the State, society or school, but everyone's responsibility, a shared basis. Well understood self-assessment exercises and external evaluation and the relationship between them becomes clear down the principle that "the assessment is the practice of the academy to examine the academy" and that the state and external entities is their only muster given the criteria and mechanisms that provide them. Set the margins of the triggering of the university and accrediting bodies, such as shared responsibility and the limits on power. Keywords: self-assessment, accreditation, external evaluation, higher education quality.