bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Mostly What We Do Is Ride Bikes”
Authors: Newhall Kristine 
Published: September 2021

Abstract
As trans visibility grows, the investment in a sex/gender binary gets more entrenched in some cultural institutions, including—and maybe especially—sports. Policies governing gender identity in sports have multiplied since the 1990s. How sports governing bodies have approached policy creation has differed widely in the past two decades, reflecting philosophical differences regarding fairness of competition and ingrained beliefs about sex and gender. This article examines the policy created by an intercollegiate cycling conference using subculture theory to explain the divergence from extant policies. It also looks at the connection to the ongoing sex/gender verification process for elite female athletes and the ways in which all policing of gender is always already a legacy of imperialist practices.
Selective Cdk9 inhibition resolves neutrophilic inflammation and enhances cardiac regeneration in larval zebrafish
Authors: Kaveh Aryan , Bruton Finnius A. , Oremek Magdalena E. M. , Tucker Carl S. , Taylor Jonathan M. , Mullins John J. , Rossi Adriano G. , Denvir Martin A. 
Published: September 2021

ABSTRACT
Sustained neutrophilic inflammation is detrimental for cardiac repair and associated with adverse outcomes following myocardial infarction (MI). An attractive therapeutic strategy to treat MI is to reduce or remove infiltrating neutrophils to promote downstream reparative mechanisms. CDK9 inhibitor compounds enhance the resolution of neutrophilic inflammation; however, their effects on cardiac repair/regeneration are unknown. We have devised a cardiac injury model to investigate inflammatory and regenerative responses in larval zebrafish using heartbeat-synchronised light-sheet fluorescence microscopy. We used this model to test two clinically approved CDK9 inhibitors, AT7519 and flavopiridol, examining their effects on neutrophils, macrophages and cardiomyocyte regeneration. We found that AT7519 and flavopiridol resolve neutrophil infiltration by inducing reverse migration from the cardiac lesion. Although continuous exposure to AT7519 or flavopiridol caused adverse phenotypes, transient treatment accelerated neutrophil resolution while avoiding these effects. Transient treatment with AT7519, but not flavopiridol, augmented wound-associated macrophage polarisation, which enhanced macrophage-dependent cardiomyocyte number expansion and the rate of myocardial wound closure. Using cdk9−/− knockout mutants, we showed that AT7519 is a selective CDK9 inhibitor, revealing the potential of such treatments to promote cardiac repair/regeneration.
CONSISTÊNCIA E CONVERGÊNCIA CONTÁBIL: RELEVANTES PARA TRANSPARÊNCIA NA ADMINISTRAÇÃO PÚBLICA?
Authors: Carlos Filho Francisco de Assis , Façanha Neto Inácio Ferreira , Rebouças Silvia Maria Dias Pedro , Guimarães Daniel Barboza 
Published: September 2021

O objetivo desta pesquisa foi identificar a relevância da consistência e da convergência contábil no nível de transparência dos municípios do Estado de Pernambuco. A amostra contou com os 184 municípios do Estado de Pernambuco. O ano analisado foi o de 2015. A análise revelou que é de 42%, em média, a transparência dos municípios pernambucanos em relação à gestão pública. Houve relação positiva e estatisticamente significativa para duas variáveis, o PIB e o tamanho da população, o que indica que, quanto maior for o PIB e a população, mais transparentes são na gestão pública serão os munícipios. Por fim, na ANACOR, os dois índices são independentes (não estão relacionados). Assim, podemos afirmar que não se regista uma relação entre o índice de transparência municipal e o índice de consistência e convergência contábil.
Enhancing innovative delivery in schools using design thinking
Authors: Gopinathan Sharmini , Kaur Anisha Haveena , Ramasamy Kanesaraj , Raman Murali 
Published: September 2021

The pandemic has created challenges in all sectors of the economy and education. Traditional teaching approaches seem futile in the new context, thus the need to constantly reinvent the delivery to meet the fast-paced changes in the education domain. Hence, Design Thinking (DT) is an alternative approach that might be useful in the given context. DT is known to be a human-centric approach to innovative problem-solving processes. DT could be employed in the delivery process to develop twenty-first-century skills and enhance creativity and innovation, in an attempt to identify alternative solutions. The study explores the role of design thinking (DT) mindset in innovative delivery among teachers. It enhances and facilitates innovative content delivery by leveraging creativity. The study targeted 131 teachers from primary and secondary schools in Malaysia. Data was collected through an online survey and was analyzed using SmartPLS to establish relationships between DT and Innovative Delivery in schools. The data was further analyzed to seek co-relations between the DT steps and the successful transformation of content delivery by teachers. The study established a framework for the application of design thinking for teachers as the primary support in developing activities for their students. The outcome of this study will help fill the gap towards creating an interesting method of delivery in schools and constantly innovating the method to suit the evolving generation. It provides an in-depth reason as to why students are not interested in the teacher's lessons which, in turn, affects their performance. This insight is crucial for the Ministry of Education and policymakers to enhance teachers’ ability to innovatively deliver content to students.
Lightning safety awareness level in Malaysia
Authors: Nazri Khairul , Lim Siow Chun , Gomes Chandima 
Published: September 2021

Introduction: Malaysia is one of the countries with the highest lightning flash density globally. While sufficiency of lightning protection system is crucial to ensure human safety against lightning strikes, the public awareness towards lightning safety is also equally important in Malaysia. Hence, this study was conducted to understand the current lightning safety awareness level of the Malaysian population. Methods: An online questionnaire survey which consists of 22 scientific statements of lightning was first developed in Malay and English. The questionnaire allows the respondent to also check their own score upon completion of the questionnaire. It was then distributed to the public for data collection. The sample size comprised of both genders, all layers of society from various educational level and social background. Results: Overall, the awareness on lightning safety amongst Malaysian is at moderate level with an average score of slightly above 50%. Urbanites scored marginally better than their rural counterparts. One’s education level does not dictate their awareness level of lightning safety. Discussion: In conclusion, the public in Malaysia needs to be better educated on lightning safety. Similar studies should be replicated in other countries experiencing similar levels of lightning activity to better understand the public’s perception on lightning.
Minimal number of morphoagronomic characters required for the identification of pineapple (Ananas comosus) cultivars in peatlands of Riau, Indonesia
Authors: Rosmaina Rosmaina , Elfianis Rita , Almaksur Abdi , ZULFAHMI Zulfahmi 
Published: September 2021

Abstract. Rosmaina, Elfianis R, Almaksur A, Zulfahmi. 2021. Minimal number of morphoagronomic characters required for the identification of pineapple (Ananas comosus) cultivars in peatlands of Riau, Indonesia. Biodiversitas 22: 3854-3862. Pineapple (Ananas comosus L Merr) is a tropical fruit that has high economic value. In Riau Province, Indonesia, pineapples grow and produce well on various types of land, including the highly acidic peatland. There are many types of pineapples grown by from generation to generation, but so far, there have been no reports regarding the diversity of pineapples in peatlands. This study aimed to determine the minimal number of characters distinguishing pineapple morphological and agronomic characters in peatlands. The observations were done on 24 local genotypes of pineapple in peatlands. Characterization were carried out on 49 morphological and agronomic characters according to the Pineapple descriptor from the International Board for Plant Genetic Resources (IBPGRI). The data were analyzed by Multivariate Analysis, in which the principal components analysis was used for qualitative and quantitative traits. Based on the results of this study, there were at least 12 characters proposed to describe pineapple in peatlands, viz. seven qualitative characters (fruit base leaf color (collar), fruit shape, bractea color, fruit eye profile, fruit eye surface, flesh color, crown attachment to fruit) and five quantitative characters (fruit weight, fruit flesh weight, plant height, number of leaves and leaf length). Out of the 49 traits observed, 12 selected characters can be used as a minimal number of characters that can be used to identify pineapple cultivars on peatland. The findings of this research are rewarding for the conservation and management of genetic resources, selection, and breeding activities of pineapple plants.
Analysis of lead (Pb) levels in water, sediment and mollusks in secondary irrigation channels in Gorontalo Province, Indonesia
Authors: Tahir Ismawati A. , LAMONDO DJUNA , BADERAN DEWI WAHYUNI K. 
Published: September 2021

Abstract. Tahir IA, Lamondo D, Baderan DWK. 2020. Analysis of lead (Pb) levels in water, sediment and mollusks in secondary irrigation channels in Gorontalo Province, Indonesia. Intl J Bonorowo Wetl 11: 1-6. This study was conducted in July-August 2020 in the secondary irrigation channels of Gorontalo Province, aimed to determine the lead content in the water, sediment and gastropods in the channels. The sampling points were located in four sub-districts, i.e., North Bulango Sub-district, Sipatana Sub-district, Central City Sub-district and Hulonthalangi Sub-district. The samples were analyzed using Atomic Absorption Spectrophotometer (AAS). The data were analyzed qualitatively by comparing them with the contamination thresholds set by the government of Indonesia. The results showed that the levels of lead in water in the four stations were 0.37 mg/L, 1.30 mg/L, 1.69 mg/L and 0.38 mg/L, respectively, in the sediment 1.1268 ppm, 0.9719 ppm, 0.7602 ppm, and 0.5290 ppm, respectively, and in each mollusk species, i.e., Bellamnya sp. 0.2924 mg/kg, Pomacea canaliculata 0.2413 mg/kg and Pomacea canaliculata 0.1873 mg/kg. The lead levels in the water, sediment and gastropods in the study sites exceeded the contamination thresholds set by the Indonesian government.
Nanometer-optical-coating-based visibly tinted films with 24-hour sub-atmospheric passive cooling
Authors: Lee Eun-Joo , Cho Jin-Woo , Kim Young-Seok , Kim Sun-Kyung 
Published: September 2021

Colored films absorb solar radiation at specific visible wavelengths, and they consequently heat up above atmospheric temperatures when exposed to sunlight. In this Letter, we report nanometer-thick TiN-based multilayers of light cyan, magenta, and yellow colors that can provide 24 h sub-atmospheric cooling when covered with high-emissivity polymers. Outdoor experiments have demonstrated that these visibly tinted films retain sub-atmospheric temperatures during daytime and nighttime. All fabricated films generated almost color-independent cooling powers and even surpassed commercial white paint at TiN thicknesses

<

5

n
m

. Our work thus highlights the potential of multispectral selective absorbers as esthetic passive coolers.
Colorectal cancer in the Linxian China Nutrition Intervention Trial: Risk factors and intervention results
Authors: Keskin Havva , Wang Shao-Ming , Etemadi Arash , Fan Jin-Hu , Dawsey Sanford M. , Abnet Christian C. , Qiao You-Lin , Taylor Philip R. 
Published: September 2021

Background
Colorectal cancer (CRC) is among the most common cancers in economically developed countries and developing world. While dietary factors are associated with risk of CRC in the West and urban China, little is known about risk or protective factors in rural China.

Methods
The Linxian General Population Nutrition Intervention Trial (NIT) cohort was established over 30 years ago to test whether daily multivitamin/mineral supplements could reduce the incidence and mortality of esophageal/gastric cardia cancer. The cohort included a total of 29,553 healthy participants 40–69 years old who were randomly assigned to supplements or placebos via a 24 fractional factorial study design. We examined risk factors for the development of CRC as well as the effects of four different nutritional factors (Factor A: retinol, zinc; B: riboflavin, niacin; C: ascorbic acid, molybdenum; D: selenium, alpha-tocopherol, beta-carotene,) on CRC incidence following 5.25 years of supplementation in this randomized, placebo-controlled intervention trial.

Results
CRC risk increased with age and height as well as piped water usage, family history of CRC, and consumption of foods cooked in oil, eggs, and fresh fruits. No effect on CRC was seen for any of these four intervention factors tested in both genders, but CRC was reduced 37% in females who received Factor D (selenium/alpha-tocopherol/beta-carotene) (RR = 0.63, 95% CI = 0.43–0.92, P = 0.016) compared to females who did not receive Factor D.

Conclusions
In this undernourished rural Chinese population, CRC risk factors in this Chinese cohort showed both similarities and differences compared to Western and urban Asian Chinese populations. Intervention results suggested a potential benefit for women supplemented with selenium/alpha-tocopherol/beta-carotene.
Heterogeneous development of children with Congenital Zika Syndrome-associated microcephaly
Authors: Aguilar Ticona Juan P. , Nery Nivison , Doss-Gollin Simon , Gambrah Claudia , Lessa Millani , Rastely-Júnior Valmir , Matos Adriana , de Paula Freitas Bruno , Borja Ana , Wunder Elsio A. , Ballalai Verena , Vieira Carina , Cruz Jaqueline S. , de Oliveira Daiana , Araujo Danielle Bastos , Oliveira Danielle B. , Nascimento Fabris Maeda Denicar Lina , Mendes Erica A. , Pereira Soares Camila , Durigon Edison L. , de Souza Ferreira Luis Carlos , Belfort Rubens , P. Almeida Antonio R. , Oliveira-Filho Jamary , Reis Mitermayer G. , Ko Albert I. , Costa Federico 
Published: September 2021

Objective
To describe the neurological and neurodevelopmental outcomes of children with Congenital Zika Syndrome (CZS) associated microcephaly beyond 2 years of age.

Method
We followed children with CZS-associated microcephaly in an outpatient clinic in Salvador, Brazil. Neurological and neurodevelopmental assessments were performed using the Hammersmith Infant Neurological Examination (HINE) and Bayley Scales of Infant and Toddler Neurodevelopment (Bayley-III) respectively.

Results
Of the 42 children included, 19 were male (45.2%); median (interquartile range) age at neurological evaluation was 28 (25–32) months, and 36 (85.7%) had severe microcephaly. HINE and Bayley-III results were completed for 35/42 (83.3%) and 33/42 (78.5%) children respectively. Bayley-III identified a severe developmental delay in 32/33 (97.0%) children while 1/33 (3.0%) had only a mild delay. In the multivariable analysis, we found that Bayley-III and HINE scores were correlated. Better HINE scores were associated with higher Bayley-III cognitive raw scores (β = 0.29; CI 95% = 0.02–0.57) and motor raw scores (β = 0.43; CI 95% = 0.04–0.82) after adjusting for head circumference, prematurity, and age at neurodevelopmental evaluation. Furthermore, we found that greater head circumference at follow up was associated with higher cognitive (β = 1.27; CI 95% = 0.01–2.53) and motor raw scores (β = 2.03; CI 95% = 0.25–3.81).

Conclusion
Children with CZS-associated microcephaly demonstrate severe neurodevelopmental delays and slower growth rates than their peers over time. Still, they have remarkably heterogeneous neurodevelopmental profiles according to neurological exam scores which correlate with their long-term outcomes. We found that HINE scores effectively captured the heterogeneity of neurological capabilities among these children and could be predictive of cognitive and motor development progress.
Dexamethasone is associated with early deaths in light chain amyloidosis patients with severe cardiac involvement
Authors: Bézard Mélanie , Oghina Silvia , Vitiello Damien , Kharoubi Mounira , Kordeli Ekaterini , Galat Arnault , Zaroui Amira , Guendouz Soulef , Gilles Floriane , Shourick Jason , Hamon David , Audard Vincent , Teiger Emmanuel , Poullot Elsa , Molinier-Frenkel Valérie , Lemonnier François , Agbulut Onnik , Le Bras Fabien , Damy Thibaud 
Published: September 2021

Background
Cardiac light chain amyloidosis (AL-CA) patients often die within three months of starting chemotherapy. Chemotherapy for non-immunoglobulin M gammopathy with AL-CA frequently includes bortezomib (Bor), cyclophosphamide (Cy), and dexamethasone (D). We previously reported that NT-ProBNP levels can double within 24h of dexamethasone administration, suggesting a deleterious impact on cardiac function. In this study, we evaluate the role of dexamethasone in early cardiovascular mortality during treatment.

Methods and findings
We retrospectively assessed 100 de novo cardiac AL patients (62% male, mean age 68 years) treated at our institute between 2009 and 2018 following three chemotherapy regimens: CyBorDComb (all initiated on day 1; 34 patients), DCyBorSeq (D, day 1; Cy, day 8; Bor, day 15; 17 patients), and CyBorDSeq (Cy, day 1; Bor, day 8; D, day 15; 49 patients). The primary endpoint was cardiovascular mortality and cardiac transplantation at days 22 and 455. At day 22, mortality was 20.6% with CyBorDComb, 23.5% with DCyBorSeq, and 0% with CyBorDSeq (p = 0.003). At day 455, mortality was not significantly different between regimens (p = 0.195). Acute toxicity of dexamethasone was evaluated on myocardial function using a rat model of isolated perfused heart. Administration of dexamethasone induced a decrease in left ventricular myocardium contractility and relaxation (p<0.05), supporting a potential negative inotropic effect of dexamethasone in AL-CA patients with severe cardiac involvement.

Conclusion
Delaying dexamethasone during the first chemotherapy cycle reduces the number of early deaths without extending survival. It is clear that dexamethasone is beneficial in the long-term treatment of patients with AL-CA. However, the initial introduction of dexamethasone during treatment is critical, but may be associated with early cardiac deaths in severe CA. Thus, it is important to consider the dosage and timing of dexamethasone introduction on a patient-severity basis. The impact of dexamethasone in the treatment of AL-CA needs further investigation.
Kottanner Jánosné memoárja
Authors: Kis Iván 
Published: September 2021

In my study I analyze a significant late-medieval memoir, known as „The Memoires of Helene Kottanner (1439–1440), written by Helene, or Elena Kottanner, an Austrian woman, daughter ofPeter Wolfram from Ödenburg (Sopron), acting in the service of Queen Elizabeth of Hungary.The source, which may be considered the oldest German memoir written by a secular woman, depicts the events of an interesting period of the medieval Hungarian history with “vividness and poignancy” (Maya Bijvoet Williamson). After the death of King Albert (1437–1439), his ambitious wife, Elizabeth – while a large part of the Hungarian nobles wanted Władysław III of Poland to be the king of Hungary – tried to maintain his own authority in Hungary (at that time she was already pregnant and hoped that her new-born will be a boy), therefore she ordered her servant, Elena Kottanner to steal the Holy Crown of Saint Stephen from the royal stronghold, Plintenburg (Visegrád). The woman and an unnamed Hungarian collaborator managed to remove the Crown secretly, rushing to the Queen with it, who within an hour of the crown’s arrival at her castle of Komorn (Komárom), bore a son, Ladislaus Posthumous (1440–1457). Three months later, the little boy was crowned King of Hungary in Stuhlweissenburg (Székesfehérvár). In her memoir, Helene Kottanner – as an eye-witness author – gives a unique, detailed and remarkable picture about these events. My main goal is to analyze the rhetorical methods, the historiographical practice presented by Helene, which can be detected in her text. I demonstrate that the servant intended to emphasize her own role in the mentioned events, and tried to legitimate the Hungarian kingship of Ladislaus Posthumous. Besides, she presented certain events as symbolic of the fate of the future king: according to Helene, God protects her and Elizabeth, and the whole undertaking, while the Devil is on the side of their enemies (Władysław III of Poland and the Hungarian nobles). Furthermore, I also intend to demonstrate what possible goals could Helene have had with her memoir. It is quite possible that the servant wrote her opus in order to get her reward for her services provided to the queen and the future king. I demonstrate this problem in context of the Hungarian political situation in the 1440s and the 1450s.
Changing foodwebs of Indian aquatic ecosystems under the threats of invasive species: An overview
Authors: Panikkar Preetha , Khan M. Feroz , Sarkar U.K. , Das B.K. 
Published: September 2021

Abstract
Biological invasions are a worldwide threat to the aquatic systems and have the potential to homogenize entire foodwebs and shift species abundance distributions to more skewed ones. Invasion impacts include effects on the foodweb structure and ecosystem functioning leading to a loss in native fish biodiversity and commercially important fisheries in many open water systems. The impacts of invasives are generally devastating as they spread in the foodweb with each species potentially interacting with multiple species. The foodweb modeling studies conducted in different inland aquatic ecosystems show that not all exotics cause a detrimental effect on the resilience of an ecosystem. Information on the foodweb structure and ecosystem properties is a prerequisite for formulating management protocols for conserving biodiversity, enhancement programmes and sustaining fisheries. The present paper reviews the impacts of invasive fishes in Indian aquatic ecosystems in the context of a changing foodweb scenario due to exotic fish species invasions. The information generated here could be applied for future research on similar ecosystems for deducing management actions.