bluuebunny/crossref_metadata_2025_split huggingface dataset:
TOMATOMET: A metabolome database consists of 7118 accurate mass values detected in mature fruits of 25 tomato cultivars
Authors: Ara Takeshi , Sakurai Nozomu , Takahashi Shingo , Waki Naoko , Suganuma Hiroyuki , Aizawa Koichi , Matsumura Yasuki , Kawada Teruo , Shibata Daisuke 
Published: April 2021

AbstractThe total number of low‐molecular‐weight compounds in the plant kingdom, most of which are secondary metabolites, is hypothesized to be over one million, although only a limited number of plant compounds have been characterized. Untargeted analysis, especially using mass spectrometry (MS), has been useful for understanding the plant metabolome; however, due to the limited availability of authentic compounds for MS‐based identification, the identities of most of the ion peaks detected by MS remain unknown. Accurate mass values of peaks obtained by high accuracy mass measurement and, if available, MS/MS fragmentation patterns provide abundant annotation for each peak. Here, we carried out an untargeted analysis of compounds in the mature fruit of 25 tomato cultivars using liquid chromatography‐Orbitrap MS for accurate mass measurement, followed by manual curation to construct the metabolome database TOMATOMET (http://metabolites.in/tomato‐fruits/). The database contains 7,118 peaks with accurate mass values, in which 1,577 ion peaks are annotated as members of a chemical group. Remarkably, 71% of the mass values are not found in the accurate masses detected previously in Arabidopsis thaliana, Medicago truncatula or Jatropha curcas, indicating significant chemical diversity among plant species that remains to be solved. Interestingly, substantial chemical diversity exists also among tomato cultivars, indicating that chemical profiling from distinct cultivars contributes towards understanding the metabolome, even in a single organ of a species, and can prioritize some desirable metabolic targets for further applications such as breeding.
Recycling Mine Tailings for a Sustainable Future Built Environment
Authors: Maruthupandian Surya , Chaliasou Napoleana Anna , Kanellopoulos Antonios 
Published: April 2021

AbstractThe future sustainable built environment focuses mainly on environmental conservation and technological innovation and development. However, with infrastructure development, the consumption of raw materials such as cement, gypsum, sand, and stones increases. Therefore, use of industrial waste as raw material in construction shall be proposed as a sustainable and environment friendly alternative. Also, the higher demand for mineral commodities have led to increased mining and hence increased mining waste. The mine tailings being the wastes from rocks and minerals processing, are generally rich in Si, Ca, Al, Mg, and Fe, and also have considerable amounts of heavy metals and metalloids such as Pb, As, Co, Cu, Zn, V, and Cr. When tailings contain sulphide minerals, it may also lead to acid mine drainage. This makes the effective and efficient recycling and reuse of mine waste a major environmental concern. However, the physical, mineralogical and chemical composition of the mine tailings renders it a suitable material for use in civil engineering applications. This paper discusses the use of mine tailings of different origins for different civil engineering applications such as bricks, ceramics, fine aggregates, coarse aggregate and cementitious binders. This approach has a potential to reduce the demand on existing natural resources to face the demands of the exponentially developing infrastructure.
Structural, spectroscopic and electrical properties of dc magnetron sputtered NiO thin films and an insight into different defect states
Authors: Salunkhe Parashurama , A.V Muhammed Ali , Kekuda Dhananjaya 
Published: April 2021

AbstractIn this article, we report a detailed study on the influence of sputter power on physical properties of the NiO films grown by DC magnetron sputtering. Structural studies carried out by Grazing Incidence X-ray diffraction (XRD) reveals the polycrystalline nature of the films with FCC phase. The crystallographic orientation (111) plane followed by (200), (220), and (311) plane were evident from the XRD spectra. The average crystallites sizes were estimated from the spectra, and the values were compared using three different plots such as Scherrer, Williamson–Hall and size–strain plot. The surface morphology was carried out by atomic force microscopy. The deposited samples show semitransparent behavior in the visible region and the estimated band gap increased from 2.70 to 3.34 eV with an increase in sputter power. Furthermore, X-ray photoelectron spectroscopy (XPS) core-level Ni2p spectra were deconvoluted and the observed $${\text{Ni}}2{\text{p}}_{{{\text{3/2}}}}$$

Ni
2

p
3/2

, $${\text{Ni}}2{\text{p}}_{{1/2}}$$

Ni
2

p

1
/
2

domain along with their satellite’s peaks were analyzed. Most importantly, XPS quantification data and Raman spectra confirm the presence of both $${\rm{Ni}}^{2+}$$

Ni

2
+

and $${\rm{Ni}}^{3+}$$

Ni

3
+

states in the NiO films. The electrical properties carried at room temperature revealed that the resistivity of the film significantly increased and a mobility of ~ 84 $${\rm{cm}}^{2}{\rm{V}}^{-1}{s}^{-1}$$

cm

2

V

-
1

s

-
1

was obtained.
Physicochemical and microbiological characteristics of urban aerosols in Krakow (Poland) and their potential health impact
Authors: Wilczyńska-Michalik Wanda , Różańska Anna , Bulanda Małgorzata , Chmielarczyk Agnieszka , Pietras Bartłomiej , Michalik Marek 
Published: April 2021

AbstractEight aerosol samples were collected in Krakow using a low-volume sampler in February and March 2019 during variable meteorological conditions and times of the day, to study their single particles’ properties (size, morphology and chemical composition analyzed using a scanning electron microscope fitted with an energy-dispersive spectrometer) and microbiological characteristics. The content of particles of different chemical compositions larger than 2.5 μm was low. Considering the number of the particles, submicron particles strongly dominated with a high content of ultrafine particles (nanoparticles). Tar ball-type particles were relatively common in the studied samples, while soot was the dominant component. Soot was present as small agglomerates composed of few particles, but also as bigger agglomerates. Metal-containing particles of various chemical characteristics were abundant, with transition metals commonly occurring in these particles. The physicochemical characteristics of aerosols indicate that despite a relatively low mass concentration, their adverse health impact could be very strong because of the high content of nanoparticles, the abundance of soot and other fuel combustion-related particles, and the high incidence of transition metal-rich particles. Microbiological analysis was based on cultures on both solid and liquid agar. The MALDI-TOF method was used for species identification—for bacteria and fungi. Twelve different species of bacteria were isolated from the collected samples of aerosols. The most frequently isolated species was Gram-positive sporulating Bacillus licheniformis. The isolated mold fungi were of the genus Aspergillus.
Bundling ecosystem services at a high resolution in the UK: trade-offs and synergies in urban landscapes
Authors: Karimi James D. , Corstanje Ron , Harris Jim A. 
Published: April 2021

Abstract
Context
Ecosystem service bundles can be defined as the spatial co-occurrence of ecosystem services in a landscape. The understanding of the delivery of multiple ecosystem services as bundles in urban areas is limited. This study modelled ecosystem services in an urban area comprising the towns of Milton Keynes, Bedford and Luton.

Objectives
The objectives of this study were to assess (1) how ecosystem service bundles scale at a 2 m spatial resolution and (2) identify and analyse the composition of ecosystem service bundles.

Methods
Six ecosystem services were modelled with the InVEST framework at a 2 m resolution. The correlations between ecosystem services were calculated using the Spearman rank correlation coefficient method. Principal Component Analysis and K-means cluster analysis were used to analyse the distributions, spatial trade-offs and synergies of multiple ecosystem services.

Results
The results showed that regulating services had the tendency to form trade-offs and synergies. There was a significant tendency for trade-offs between supporting service Habitat quality and Pollinator abundance. Four bundle types were identified which showed specialised areas with prevalent soil erosion with high levels in water supply, areas with high values in nutrient retention, areas with high levels in carbon storage and urban areas with pollinator abundance.

Conclusions
This study demonstrates the existence of synergies and trade-offs between ecosystem services and the formation of ecosystem service bundles in urban areas. This study provides a better understanding of the interactions between services and improve the management choices in ecosystem service provision in urban and landscape planning.
A Multidimensional Approach to Measuring Quality of Employment (QoE) Deprivation in Six Central American Countries
Authors: González Pablo , Sehnbruch Kirsten , Apablaza Mauricio , Méndez Pineda Rocío , Arriagada Veronica 
Published: April 2021

AbstractThis paper proposes a methodology for measuring Quality of Employment (QoE) deprivation from a multidimensional perspective in six Central American countries (Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, and Panama) using a dataset specifically designed to measure employment conditions. Building on previous work on multidimensional poverty and employment indicators, the paper uses the Alkire/Foster (AF) method to construct a synthetic indicator of the QoE at an individual level. It selects four dimensions that must be considered as essential to QoE deprivation: income, job stability, job security and employment conditions. These dimensions then subdivide into several indicators, a threshold for each indicator and dimension is established before defining an overall cut-off line that allows for the calculation of composite levels of deprivation. The results generated by this indicator show that Central American countries can be divided into three distinct and robust performance groups in terms of their QoE deprivation. Overall, approximately 60% of the deprivation levels are attributable to non-income variables, such as occupational status and job tenure. The methodology used can allow policymakers to identify and focus on the most vulnerable workers in a labour market and highlights the fact that having a formal written contract is no guarantee of good job quality, particularly in the case of women.
In planta test system for targeted cellular mutagenesis by injection of oligonucleotides to apical meristem of maize seedlings
Authors: Rádi Feríz , Nagy Bettina , Ferenc Györgyi , Török Katalin , Nagy István , Zombori Zoltán , Dudits Dénes , Ayaydin Ferhan 
Published: April 2021

AbstractGenome-editing tools from Oligonucleotide-Directed Mutagenesis (ODM) to CRISPR system use synthetic oligonucleotides for targeted exchange of nucleotides. Presently, majority of genome-editing protocols are dependent on the in vitro cell or tissue culture systems with somaclonal variation, and limitations in plant regeneration. Therefore, here, we report an alternative in planta cellular test system for optimization of the ODM, based on the injection of oligonucleotide solution into the apical meristematic region of haploid maize seedlings. Using 5′-fluorescein-labeled oligonucleotides, we detected accumulation of synthetic DNA molecules in cells of the shoot apical meristem and of the vascular bundles of leaf primordia. For silencing or knocking down of the phytoene desaturase gene in somatic cells, 41-mer long single-stranded oligonucleotides with TAG stop codon were injected into maize seedlings. We detected out-growing M1 plantlets that developed leaves with white stripes or pale-green color. Confocal microscopy of white stripes showed that in addition to the chlorophyll fluorescence-deficient tissue region, chlorophyll containing cells are present in white stripes. The Ion Torrent sequencing of DNA samples from the white stripes indicated 0.13–1.50% read frequency for the TAG stop codon in the phytoene desaturase gene. Appearance of chlorotic abnormalities supports the mutagenic nature of oligonucleotide molecules after injection into the shoot apical meristem region of maize seedling. The described protocol provides basis for early seedling stage characterization of functionality of a mutagenic oligonucleotide with different chemistry and testing efficiency of various treatment combinations at plant level.
CSNK2B contributes to colorectal cancer cell proliferation by activating the mTOR signaling
Authors: Yu Shijun , Hu Qingqing , Fan Kailing , Yang Chen , Gao Yong 
Published: April 2021

AbstractThe function of Casein kinase 2 beta (CSNK2B) in human malignancies has drawn increasing attention in recent years. However, its role in colorectal cancer (CRC) remains unclear. In the present study, we aimed to explore the expression and biological functions of CSNK2B in CRC. Public gene expression microarray data from online database and immunohistochemistry analysis demonstrated that CSNK2B was highly expressed in CRC tissues than in normal tissues. In vitro and in vivo cellular functional experiments showed that increased CSNK2B expression promoted CRC cell viability and tumorigenesis of CRC. Further western blots and rescue experiments confirmed that CSNK2B promoted CRC cell proliferation mainly by activating the mTOR signaling pathway. These findings identified CSNK2B as a novel oncogene contributing to the development of CRC.
Saving Up for a Rainy Day? Savings Groups and Resilience to Flooding in Dar es Salaam, Tanzania
Authors: Panman Alexandra , Madison Ian , Kimacha Nyambiri Nanai , Falisse Jean-Benoît 
Published: April 2021

AbstractThis paper explores the role of savings groups in resilience to urban climate-related disasters. Savings groups are a rapidly growing phenomenon in Africa. They are decentralized, non-institutional groups that provide millions of people excluded from the formal banking sector with a trusted, accessible, and relatively simple source of microfinance. Yet there is little work on the impacts of savings groups on resilience to disasters. In this paper, we use a combination of quantitative and qualitative evidence from Dar es Salaam (Tanzania) to shed new light on the role that savings groups play in helping households cope with climate-related shocks. Drawing on new data, we show that approximately one-quarter of households have at least one member in a group, and that these households recover from flood events faster than those who do not. We further argue that the structure of savings groups allows for considerable group oversight, reducing the high costs of monitoring and sanctioning that often undermine cooperative engagement in urban areas. This makes the savings group model a uniquely flexible form of financing that is well adapted to helping households cope with shocks such as repeated flooding. In addition to this, we posit that they may provide a foundation for community initiatives focusing on preventative action.
On equilibrium Metropolis simulations on self-organized urban street networks
Authors: Benoit Jérôme G. M. , Jabari Saif Eddin G. 
Published: April 2021

AbstractUrban street networks of unplanned or self-organized cities typically exhibit astonishing scale-free patterns. This scale-freeness can be shown, within the maximum entropy formalism (MaxEnt), as the manifestation of a fluctuating system that preserves on average some amount of information. Monte Carlo methods that can further this perspective are cruelly missing. Here we adapt to self-organized urban street networks the Metropolis algorithm. The “coming to equilibrium” distribution is established with MaxEnt by taking scale-freeness as prior hypothesis along with symmetry-conservation arguments. The equilibrium parameter is the scaling; its concomitant extensive quantity is, assuming our lack of knowledge, an amount of information. To design an ergodic dynamics, we disentangle the state-of-the-art street generating paradigms based on non-overlapping walks into layout-at-junction dynamics. Our adaptation reminisces the single-spin-flip Metropolis algorithm for Ising models. We thus expect Metropolis simulations to reveal that self-organized urban street networks, besides sustaining scale-freeness over a wide range of scalings, undergo a crossover as scaling varies—literature argues for a small-world crossover. Simulations for Central London are consistent against the state-of-the-art outputs over a realistic range of scaling exponents. Our illustrative Watts–Strogatz phase diagram with scaling as rewiring parameter demonstrates a small-world crossover curving within the realistic window 2–3; it also shows that the state-of-the-art outputs underlie relatively large worlds. Our Metropolis adaptation to self-organized urban street networks thusly appears as a scaling variant of the Watts–Strogatz model. Such insights may ultimately allow the urban profession to anticipate self-organization or unplanned evolution of urban street networks.
Recoverable Autonomous Sonde for subglacial lakes exploration: heating control system design
Authors: Yu Haibin , Zhu Tianxin , Jiang Xiao , Tang Yongzhen , Li Xiaodong , Li Chong , Huang Shengmiao , Shi Jianguang , Sun Youhong , Talalay Pavel , Fan Xiaopeng , Li Xiao , Li Yazhou , Peng Shilin 
Published: April 2021

AbstractDrilling and sampling are the most direct and effective methods available to study Antarctic subglacial lakes. Based on the Philberth probe, a Recoverable Autonomous Sonde (RECAS) allows for in situ lake water measurement and sampling, through the addition of an upper thermal tip and a cable recoiling mechanism. RECAS-200, a prototype of RECAS, has a drilling depth of 200 m, a surface supply voltage of 800 VAC and a downhole power of ~9.6 kW during drilling. In this study, a heating control system for RECAS-200 was designed. The system avoids the need for high-power step-down converters, by separating heating power from control power, thereby reducing the overall weight of the probe and avoiding the need to increase cable diameter. We also introduce a self-developed, small, solid-state, 800 VAC power regulator and a fuzzy PID temperature control algorithm. Their purpose was to manage the power adjustment of each heating element and to provide closed-loop temperature control of certain heating elements which can easily burn out due to overheating. Test results indicated that the proposed RECAS-200 heating control system met all our design specifications and could be easily assembled into the RECAS-200 probe.
I Came, I Saw, I Voted: Distance to Polling Locations and Voter Turnout in Ontario, Canada
Authors: Garnett Holly Ann , Grogan Sean 
Published: April 2021

AbstractHow accessible are polling locations in Canada? This article explores, for the first time in the Canadian context, the distance that voters may travel to get to their polling stations. It assembles a new set of data from the province of Ontario, mapping the distance between polling locations and a representative point in the polling division, using a variety of measures, including walking, driving and public transit times. It estimates the relationship between these distances and travel times and socio-demographic characteristics of each polling division, finding noteworthy relationships between these distances and the percentage of minority populations (both immigrant and Indigenous) in the polling division. This article also presents a potential negative, but nonlinear, relationship between distances and travel times and turnout, contributing to our understanding of how voters’ rational calculus of voting may be related to the locations of polling stations.
Improving the management of suspected tonsillitis and peritonsillar abscess referred to ENT – a coronavirus disease 2019 service improvement
Authors: Cereceda-Monteoliva N , Devabalan Y , Lorenz H , Magill J C , Unadkat S , Rennie C 
Published: April 2021

AbstractBackgroundThe impact of coronavirus disease 2019 on healthcare has led to rapid changes in otolaryngology service provisions. As such, new standard operating procedures for the management of suspected tonsillitis or quinsy were implemented in our centre.MethodsA retrospective audit was performed of acute referrals to ENT of patients with suspected tonsillitis, peritonsillar cellulitis or quinsy, during the 10 weeks before (group 1) and 10 weeks after (group 2) implementation of the new standard operating procedures.ResultsGroup 2 received fewer referrals. Fewer nasendoscopies were performed and corticosteroid use was reduced. The frequency of quinsy drainage performed under local anaesthetic increased, although the difference was not statistically significant. Hospital admission rates decreased from 56.1 to 20.4 per cent, and mean length of stay increased from 1.13 to 1.5 days. Face-to-face follow up decreased from 15.0 to 8.2 per cent, whilst virtual follow up increased from 4.7 to 16.3 per cent. There were no significant differences in re-presentation or re-admission rates.ConclusionManagement of suspected tonsillitis or quinsy using the new standard operating procedures appears to be safe and effective. This management should now be applied to an out-patient setting in otherwise systemically well patients.
Preparing for translocations of a Critically Endangered petrel through targeted monitoring of nest survival and breeding biology
Authors: Fischer Johannes H. , Wittmer Heiko U. , Taylor Graeme A. , Debski Igor , Armstrong Doug P. 
Published: April 2021

Abstract
The population of the recently-described Whenua Hou diving petrel Pelecanoides whenuahouensis comprises c. 200 adults that all breed in a single 0.018 km2 colony in a dune system vulnerable to erosion. The species would therefore benefit from the establishment of a second breeding population through a translocation. However, given the small size of the source population, it is essential that translocations are informed by carefully targeted monitoring data. We therefore modelled nest survival at the remaining population in relation to potential drivers (distance to sea and burrow density of conspecifics and a competitor) across three breeding seasons with varying climatic conditions as a result of the southern oscillation cycle. We also documented breeding phenology and burrow attendance, and measured chicks, to generate growth curves. We estimated egg survival at 0.686, chick survival at 0.890, overall nest survival at 0.612, and found no indication that nest survival was affected by distance to sea or burrow density. Whenua Hou diving petrels laid eggs in mid October, eggs hatched in late November, and chicks fledged in mid January at c. 86% of adult weight. Burrow attendance (i.e. feeds) decreased from 0.94 to 0.65 visits per night as chicks approached fledging. Nest survival and breeding biology were largely consistent among years despite variation in climate. Nest survival estimates will facilitate predictions about future population trends and suitability of prospective translocation sites. Knowledge of breeding phenology will inform the timing of collection of live chicks for translocation, and patterns of burrow attendance combined with growth curves will structure hand-rearing protocols. A tuhinga whakarāpopoto (te reo Māori abstract) can be found in the Supplementary material.