bluuebunny/crossref_metadata_2025_split huggingface dataset:
Agronomic biofortification with zinc on yield, nutritional quality, nutrient uptake and economics of babycorn
Authors: Amutham G. Tamil , Karthikeyan R. , Thavaprakaash N. , Bharathi C. 
Published: July 2021

The aim of the present study was to investigate the effect of agronomic biofortification with zinc on yield, nutritional quality, nutrient uptake and economics of babycorn under irrigated condition. The observations on yield viz., green cob yield, babycorn yield and green fodder yield and quality parameters (crude protein, total soluble sugars, starch and Zn content) were recorded at harvest stage. The nutrient uptake was analysed at different growth stages and economic indices viz., the total cost of cultivation, gross return, net return and benefit cost ratio were worked out for various zinc fertilization treatments. Increased green cob yield and babycorn yield was recorded higher in soil application of zinc sulphate @ 37.5 kg ha-1 along with a foliar spray of 1.0 % on 20 and 40 DAS. Quality parameters of babycorn viz., crude protein, total soluble sugars, starch and Zn content in corn were significantly increased with soil application of ZnSO4 @ 37.5 kg ha -1 along with a foliar spray of 0.5% at 20 and 40 DAS that recorded higher values of these quality characters. Plant nutrient uptake of N, K and Zn in babycorn was significantly increased with the application of ZnSO4 @ 37.5 kg ha -1 in soil with foliar spray of 0.5% at 20 and 40 DAS. Higher net monetary returns and B: C ratio were obtained with application of ZnSO4@ 37.5 kg ha -1in soil with foliar spray @ 0.5% on 20 and 40 DAS.
Blood glucose concentration measured in EDTA/F plasma and serum in a referral clinical laboratory in Nepal
Authors: Pant Vivek , Gautam Keyoor , Pradhan Santosh , Pyakurel Devish , Shrestha Abha 
Published: July 2021

Background: Sodium fluoride tubes or serum separator tubes are mostly used for blood glucose estimation in the clinical laboratories of Nepal. The study aimed to investigate the stability of glucose in samples collected in serum separator tubes and sodium fluoride/sodium ethylenediaminetetraacetic tubes by comparing the glucose concentration at 30 minutes and 4 hours collected and handled differently to simulate prolonged sample transport between venipunctures, centrifugation, and measurement.Materials and Methods: Samples were collected from healthy volunteers into two different serum separator tubes and two different sodium fluoride/sodium ethylenediaminetetraacetic tubes. Glucose concentration was measured at 30 minutes after venipuncture and compared with results from the same samples analyzed at four hours and with the results from tubes centrifuged with a delay of 4 hours. Differences between baseline and respective delayed analyzed glucose values for each tube type were tested using the Student’s paired t-test and Deming regression.Results: When comparing plasma glucose at 30 minutes, glycolysis caused a relative reduction of the glucose concentration in serum at 30 minutes of 3.1 %, which is only slightly less than at 4 hours (3.7 %). This is still substantially more than the reduction in plasma at 4 hours (1.3 %). Surprisingly, the difference between plasma glucose at 30 minutes and serum glucose at 4 hours was only 1.9% which is not clinically significant.Conclusions: The Na-F/Na2 EDTA tubes and serum separator tubes can be used interchangeably for analysis of blood glucose up to 4 hours if centrifuged within 30 minutes.
Mixed adenoneuroendocrine tumour with squamous differentiation: a case report
Authors: Thomas Irene , Surendran Divya , Augustine Joy 
Published: July 2021

Mixed adenoneuroendocrine carcinoma is a rare neoplasm with both epithelial and neuroendocrine components. To date, only a few cases of this neoplasm have been reported in the literature among which gastric mixed adenoneuroendocrine carcinoma is very rare. We are reporting a case of gastric mixed adenoneuroendocrine carcinoma with squamous cell differentiation. Histopathological features, biological behaviour and the treatment of this rare tumour type have been discussed briefly.
Cyclin D1 expression and its correlation with clinicopathological variables in colorectal carcinoma
Authors: Sharma Neha , Singh Taranveer , Kaur Arshdeep , Manjari Mridu , Bashir Shazia 
Published: July 2021

Background: This study was conducted to evaluate the expression of Cyclin D1 in colorectal carcinoma, and to correlate Cyclin D1 positivity with the grade of the tumor along with other parameters such as age, tumor location, lymph node metastasis, and vessel invasion.Materials and Methods: The present cross-sectional study was conducted on 40 proven cases of colorectal carcinoma from October 2015 to October 2017. The tissues were fixed, processed, and stained with hematoxylin and eosin followed by immunohistochemical staining with Cyclin D1 using monoclonal antibodies.Results: 75% of the cases were conventional adenocarcinoma while the rest were mucinous adenocarcinoma. Of the total colorectal carcinomas,12.5% were Grade I, 50% were Grade II and 37.5% cases were Grade III. Cyclin D1 positivity was seen in 60% of cases with the most positivity in grade II tumors. A statistically significant correlation of Cyclin D1 was seen with age group (5th- 6th decade) and histological type of tumor. No significant correlation was seen of Cyclin D1 with lymph node involvement, depth of invasion, vascular invasion, or perineural invasion. A significant statistical correlation was seen with Crohn’s-like reaction and peritumoral lymphocytic response.Conclusions: Thus, it was concluded that a highly statistically significant correlation was seen with age group (5th- 6th decade) and histological type of tumor. No significant correlation was seen with Cyclin D1 expression with lymph node involvement, depth of invasion, vascular invasion, or perineural invasion.
Mucinous Carcinoma of the breast with micropapillary pattern and psammomatous calcification: A case study.
Authors: Bhattacharjee Koushiki , Valiathan Manna 
Published: July 2021

Mucinous carcinoma with a micropapillary pattern is an unusual form of Invasive breast cancer exhibiting dual mucinous and micropapillary differentiation. The present case is of a 47-year-old nulliparous female who presented with an incidental finding of a hard lump in her left breast. Mammography revealed a BIRADS 4 lesion. Modified radical mastectomy was done and the specimen was grossed, revealing a tumor of 3x2.6x2.6 cm in the outer quadrant. Microscopy revealed the tumor having extracellular mucin pools with floating psammoma bodies and focal micropapillary pattern. Four of the twenty-six lymph nodes sampled were found to have tumor deposits. The micropapillary pattern was maintained in the metastatic deposits. Immunohistochemistry revealed ER and PR positivity and Her2Neu negativity. EMA corroborated the findings. It is important to recognize the micropapillary pattern in mucinous carcinomas of the breast as these tumors tend to be more aggressive than pure mucinous breast lesions.
Neuronal hyperplasia in clinically diagnosed acute appendicitis: A histopathological study in tertiary care centre
Authors: Parmar Riddhi A , Dixit Riti P , Patel Keval Arvindbhai , Sharma Bhawana S , Dave Jigna 
Published: July 2021

Background: Acute appendicitis is one of the most common general surgical emergencies. Around 20-25% of patients who have an appendectomy done are found not to have acute appendicitis on histopathological examination. There is increasing evidence of the involvement of the enteric nervous system, in the immune regulation and monitoring the inflammatory responses. The present study was done to elucidate if neuronal changes in the appendix could be the cause of clinical acute.Materials and methods: Hospital records of 60 cases who were diagnosed as acute appendicitis clinically and who underwent appendectomy either laparoscopic or open, were reviewed. Histopathological records of these resected appendices submitted to the department of histopathology, GAIMS, G.K. General Hospital Bhuj were reviewed for one year for the presence or absence of acute appendicitis or neuronal hyperplasia. Routine Haematoxylin and Eosin stain and S-100 protein staining was done on all these 60 cases.Results: Out of these 60 specimens of appendices received, histopathological examination revealed neuronal hyperplasia in the submucosa and muscularis layer on all the 60 cases. Grading of neuronal hyperplasia was done in all the cases. Out of these 60 specimens of appendices, histopathological examination revealed 48 cases of histopathologically positive acute appendicitis and 12 cases of histopathologically negative acute appendicitis.Conclusions: Neuronal hyperplasia has an important role in the pathogenesis of appendiceal colic in patients with both histopathologically positive acute appendicitis and histopathologically negative acute appendicitis
The Psychological Condition of STIQ Amuntai Student’s in Learning Arabic
Authors: Rifa'i Ahmad , Hidayati Erma , Purnamasari S. 
Published: July 2021

This study discussed the psychological condition of STIQ Amuntai students in learning Arabic and the factors that affect the psychological condition of STIQ Amuntai students in learning Arabic. This study aimed to determine the psychological condition of students of the Al-Quran College of Science in learning Arabic, both students with religious education background such as Aliyah/Islamic boarding schools and students with public schools background such as high schools, vocational schools. This study also discussed the factors that influenced the psychological condition of students during learning Arabic. This research is a qualitative descriptive study. The data were collected by observation, interviews, and documentation. The process of data analysis is by examining all observed data from related to Arabic learning, checking the validity of the findings by author participation. The conclusion from this study can be argued that the psychological condition of STIQ Amuntai students in learning Arabic was not good, they were less enthusiastic and confused when learning Arabic. It is due to several factors, namely: diverse school backgrounds and lack insights about Arabic such as a lack of management of Arabic learning materials. Beside that they were faced with various other subject matter and the obligation to memorize al-Quran, thus the interest and enthusiasm gradually diminished. The lecturer background is in accordance with their education and the syllabus is in line with the campus syllabus. The teaching methods were not suitable for students abilities. Campus environment that did not use Arabic both from superiors and students. There were inadequate facilities and infrastructure, such as language laboratories that were not used according to their function.
Quality of Life following Chemoradiotherapy for Localized Muscle Invasive Bladder Carcinoma: A Systematic Review
Authors: de Ruiter Ben-Max , Keijzer Abel N. , Hulshof Maarten C.C.M. , Bins Adriaan D. , de Reijke Theo M. , Oddens Jorg R. 
Published: July 2021

BACKGROUND: Health Related Quality of Life (HRQoL) is an important factor regarding treatment for localized Muscle Invasive Bladder Carcinoma (MIBC), as it may affect choice of treatment. The impact of chemoradiotherapy (CRT) for MIBC on HRQoL has not yet been well-established. OBJECTIVE: To systematically evaluate evidence regarding HRQoL as assessed by validated questionnaires after definitive treatment with CRT for localized MIBC. METHODS: We performed a critical review of PubMed/MEDLINE, EMBASE, and the Cochrane Library in October 2020. Two reviewers independently screened articles for eligibility and assessed the methodological quality of the included articles using Joanna Briggs Institute critical appraisal tools. A narrative synthesis was undertaken. RESULTS: Of 579 articles identified, 11 studies were eligible for inclusion, including three RCTs and 8 non-randomized studies, reporting on HRQoL data for 606 CRT patients. Global health declined at End of Treatment (EoT), and recovered 3 months following treatment. Physical function declined from baseline at EoT and recovered between 3 and 24 months and was maintained at 5 years follow up. CRT had little effect on social and emotional function in the short-term, but HRQoL results in the long-term were lower compared to the general population. Urinary function declined from baseline at EoT, but returned to baseline at 6 months following CRT. After initial decline in bowel function, a complete return to baseline occurred 4 years following treatment. The majority of studies assessing sexual function showed no to little effect on sexual function. CONCLUSIONS: HRQoL recovers to baseline within 3 months to 2 years in almost all domains. The amount of available evidence regarding HRQoL following CRT for MIBC is limited and the quality of evidence is low.
Effect of the frequency of weight-free vibration training on the isokinetic strength of knee muscles in juvenile football players
Authors: Cheng Liang , Xu Hanxiao , He Benxiang , Zhou Jianan 
Published: July 2021

BACKGROUND: Vibration training can affect strength improvement. However, the role of the vibration frequency, in terms of knee muscle strength, is unclear. OBJECTIVE: To evaluate the effect of vibration training with the same amplitude and different frequencies on the isokinetic muscle strength of the knee in juvenile football players. METHODS: Juvenile football players were divided into four groups: low frequency ([Formula: see text] 13, 25 Hz), medium frequency ([Formula: see text] 14, 40 Hz), high frequency ([Formula: see text] 14, 50 Hz), and control ([Formula: see text] 13). The frequency groups completed 12 weeks of weight-free vibration training (three times/week) with the same amplitude (3 mm) but different frequency. RESULTS: Compared with baseline, the peak extension torque of the knee at 60[Formula: see text]/s and 240[Formula: see text]/s increased by 8.4% and 12.9%, respectively, in the medium-frequency group, and by 8.9% and 15.5%, respectively, in the high-frequency group. The extensor endurance (the ability of joint muscle groups to maintain a force output over time) of the knee in the high-frequency group increased by 4.3%. At 12 weeks, the high-frequency group had greater knee extensor endurance than the low- and medium-frequency groups. CONCLUSION: In juvenile football players, weight-free vibration training at 40 Hz and 50 Hz improves peak torque of the knee extensors at 60[Formula: see text]/s and 240[Formula: see text]/s, while training at 50 Hz improves endurance of the knee extensors.
The Association between Urinary Tissue Inhibitor Metalloproteinase 2 (TIMP-2) and Insulin-like Growth Factor Binding Protein 7 (IGFBP-7) and Renal Recovery in Acute Kidney Injury
Authors: Emilia  , Zulkhair Ali  , Ian Effendi  , Novadian  , Suprapti  , Mediarty  , Taufik Indrajaya  , Mgs. Irsan Saleh  
Published: July 2021

Background. Acute kidney injury (AKI) is a common and serious medical condition associated with significant increases in morbidity, mortality, cost of care and non recovery of kidney function that leads to progression to chronic kidney disease. Cell cycle arrest is implicated in the pathogenesis and repair process following AKI. The urinary cell-cycle arrest markers tissue inhibitor of metalloproteinase-2 (TIMP-2) and insulin-like growth factor binding protein 7 (IGFBP-7) have been utilized to predict the risk of AKI in many studies from specific population with good performance. However, their use in predicting recovery is still lacking. The aim of this study was to determine the association between two novel AKI biomarkers, urinary TIMP2 and IGFBP7 and renal recovery after 7 days of treatment in AKI patients at Dr. Mohammad Hoesin Hospital Palembang.
Method. This was a prospective cohort study conducted in dr. Mohammad Hoesin Hospital Palembang from January 2021 until March 2021. Subjects enrolled in this study were patients whom diagnosed AKI based on KDIGO 2012 criteria. Urine samples were collected upon patients’ enrollment within 24 hours of AKI diagnosis. We utilized Sandwich Enzyme Linked Immunosorbant Assay (ELISA) method to detect urinary TIMP-2 and IGFBP-7 levels. The primary outcome is recovery from AKI after 7 days of treatment. Chi square test is used to analyze the association between urinary TIMP-2 and IGFBP-7 levels and renal recovery.
Results. There were 70 subjects, only 22 of them were recovered after 7 days (31%). Median of urinary TIMP-2 and IGFBP-7 was 0,0047(0,0001-0,1439) [(ng/ml)2/1000]. There was significant association between urinary TIMP2 and IGFBP7 and renal recovery (p=0,027; OR 3,19; 95% CI 1,116-9,128).
Conclusion. There was significant association between urinary TIMP2 and IGFBP7 and renal recovery in AKI patients.
ORIGINAL RESEARCH ARTICLE: EXPRESSION OF SYCOSIS MIASM IN TODAY’S ERA
Authors: Joshi Nidhi , Shah K.B , Chatterjee Arpita , Mangukiya Radha , Panda B.P 
Published: July 2021

Background: The word miasm means an infection. Hippocrates was the first who use the term "miasm" which has its origins in the Greek word for taint or fault. He anticipated that certain infectious diseases were transmitted to humans by air and water tainted by miasms. Hahnemann thought that the life power is infected by certain factors and this infection creates the disease. Dr. Hahnemann has recognized three special forms which he has designated as PSORA, SYCOSIS AND SYPHILIS. Which are recognized as ‘Miasm’
Objectives: The objective of the study is to understand the Expression of Sycosis miasm in Today’s Era.
Methods: This Prospective study includes 50 cases that were randomly selected which had predominantly sycotic expression irrespective of age, sex and religion. The symptoms in the case were analyzed for the sycosis expressions. Investigation was carried out as and when required as per the case. The remedy was selected on the basis of totality of symptoms. The remedies were used in various potencies with repetition of doses as per the requirement of the case. The Homoeopathic remedies were selected from Standard Homoeopathic Pharmacy, Response was analyzed into 3 criteria: Mild Improvement, Moderate Improvement, Status quo, Left the treatment.
Results: 50 cases of sycosis expression, both the genders of different age and different family background were analyzed and examined for response the homeopathic treatment. Expression of sycosis miasm was observed more in 31-40 years of age group. In general, sycosis predominantly seen in Male 26 cases. The common mental expression which was easily found out was dominating nature and desire for company and most peculiar was anger, which was expressed in different-different ways e.g., Anger at trifles, anger when contradicted, with abusive language or even throwing things when angry. In physical expression craving for such as sweets and spices. This miasm has aggravation at night in the research it is observed majority complaints of sycosis aggravated at night. The prominent disease conditions observed were hypertension 16%, renal calculi 12%, and diabetes mellitus 9%, hemorrhoids and hypothyroidism 7%, and gout, BPH, DNS, ovarian cyst, fibroids 5% respectively. The medicines selected on the totality of symptoms including miasmatic expression gave moderate improvement in 32% of cases where as mild improvement was observed in 40% of cases. The medicine found to be effective were anti-sycotic medicines like Medorrhinum, Nat. mur, Calc.carb, Apis etc. Lycopodium was prescribed in 20% of cases.
Conclusion: From our study we would like to conclude that sycosis is flourishing miasm in many directions in this world. Along with it, it is most mischievous and difficult to conclude on mental aspect. Because we cannot grab sycotic person from their mind. Here I have made an effort to find out the common features of sycosis in this era which we can effortlessly find out and get from people.
Keywords: miasm, sycosis
PENINGKATAN MINAT BERINVESTASI MELALUI LITERASI KEUANGAN PASAR MODAL
Authors: Chyntia Ovami Debbi , Sari Lubis Anggia 
Published: July 2021

Tujuan dari kegiatan Program Layanan Masyarakat melalui PKM (Program Kemitraan Masyarakat) adalah untuk meningkatkan kesadaran, ketertarikan dan pengetahuan siswa mengenai literasi keuangan pasar modal. Mitra kegiatan pengabdian kepada masyrakat ini adalah siswa SMK Swasta Al Washliyah 3 Medan yang berada di jalan Garu II Medan. Permasalahan mitra yaitu ketidaktahuan siswa tentang pasar modal, kurangnya kesadaran dan tertarik dengan investasi yang bersifat jangka panjang. Solusi yang akan dilakukan dalam Program IBM ini adalah sosialisasi untuk peningkatan pengetahuan akan pasar modal dan kesadaran serta menumbuhkan ketertarikan untuk berinvestasi jangka panjang sejak muda. Metode yang diterapkan adalah klasikal dan individual. Metode pendekatan ini dalam bentuk ceramah dan praktek. Pendekatan individual dilakukan pada saat praktek berupa memberi sosialisasi pengetahuan mengenai literasi keuangan pasar modal serta meningkatkan kesadaran dan ketertarikan siswa dalam berinvestasi di pasar modal. Hasil yang diperoleh yaitu para guru dapat meningkatkan pemahaman dan pengetahuan tentang pasar modal serta kesadaran dan ketertarikan guru terhadap investasi dalam pasar modal.
PENGEMBANGAN BUDIDAYA JAMUR TIRAM DI LINGKUNGAN KAMPUS FMIPA UNIMED
Authors: Restuati Martina , Shafwan S. Pulungan Ahmad , Andi Syahputra Ricky , Sutiani Ani , Maulim Silitonga Pasar , Pratiwi Nanda , Gultom Rahmad 
Published: July 2021

Universitas Negeri Medan sebagai kampus yang memiliki Jurusan Biologi yang mempelajarai berbagai jamur dan pekembangannya dalam matakuliah mikrobiologi serta didukung oleh lahan yang mendukung untuk melakukan pengembangan jamur. Mengingat cukup potensi budidaya jamur tiram di Unimed khususnya FMIPA diperlukan suatu upaya untuk meningkatkan pengetahuan mahasiswa dan masyarakat sekitar. Upaya yang dilakukan adalah memberikan pelatihan bagaimana cara pengembangan tanaman jamur tiram melalui lima tahapan, yaitu : (1) pemamparan materi tentang pengemasan jamur tiram, (2) perizinan usaha jamur tiram, (3) sertifikasi halal produk jamur tiram, (4) Pendampingan perizinan dan sertifikasi halal, (5) review terhadap pelatihan yang telah dilaksanakan serta menarik kesimpulan. Dengan diberikannya pengetahuan dan pemahaman dalam melakukan pengembangan budidaya tanaman jamur tiram akan menjadi bekal bagi para mahasiswa untuk pengembangan yang lebih maksimal sehingga dapat dipasarkan ke supermarket dan memberikan income generate bagi FMIPA Unimed khususnya Jurusan Biologi. Dengan diberikannya pengetahuan dan pemahaman dalam melakukan budidaya tanaman jamur tiram akan menjadi bekal bagi para mahasiswa untuk pengembangan yang lebih maksimal dan pemberian pelatihan budidaya jamur tiram dan dihasilkan akan memiliki nilai ekonomis cukup tinggi. Kegiatan ini dapat membantu mahasiswa sebagai bekal untuk berwirausaha dan sebagai sarana pembelajaran. Selain itu kegiatan ini akan membantu untuk mewujudkan impian FMIPA Unimed menjadikan menjadi kampus penghasil jamur tiram.