bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantitative trait locus mapping of five significant quality traits such as crude protein content of tetraploid hybrid crested wheatgrass in multiple environments
Authors: Yang Dongsheng , Yu Xiaoxia , Yu Zhuo , Li Jiaqi , Li Jingwei , Lu Qianqian , Wu Guofang 
Published: November 2021

AbstractAgropyron is an important germplasm material of the genetic improvement for Gramineae forage and Triticeae crops. In the present research, in order to determine the stable and major quantitative trait loci (QTLs) controlling five significant quality traits, a total of 115 individuals from F2 segregation population of tetraploid hybrid crested wheatgrass and their parents were used as materials. On the basis of the ultra‐high density molecular genetic linkage map of tetraploid crested wheatgrass constructed with single nucleotide polymorphism (SNP) markers, we first determined QTLs for the phenotypic data of five quality traits in three different environments (Hohhot‐2018, Hohhot‐2019 and Tongliao‐2019) in 2 years (2018 and 2019) by Map QTL 6.0 software. The results showed that a total of 28 QTLs controlling quality traits of wheatgrass were located on 11 linkages (LGs), including LG1, LG2, LG3, LG4, LG6, LG7, LG8, LG9, LG12, LG13 and LG14. Among them, there were two QTLs for crude protein content (CPC), four QTLs for water‐soluble carbohydrate content (WSCC), 12 QTLs for starch content (SC), five QTLs for phosphorus content (PC) and five QTLs for calcium content (CC), which accounted for 10.1% to 21.6% of the phenotypic variation and all were major QTLs of genetic contribution rate >10%. However, only six stable QTLs were detected at least in two environments and in the mean environment data, including one for CPC (qCpc4‐1), one for WSCC (qWscc4‐2), two for SC (qSc1‐2, qSc9‐12), one for PC (qPc4‐4) and one for CC (qCc4‐2). These QTLs determining five traits would provide a theoretical basis for further fine mapping and the molecular marker‐assisted selection of elite gene in tetraploid crested wheatgrass.
Excess weight gain in the paediatric bleeding disorders population: Impact of the COVID‐19 Pandemic
Authors: Malcolmson Caroline , Tetzlaff Deirdre , Maguire Bryan , Wakefield Cindy , Carcao Manuel , Bouskill Vanessa 
Published: November 2021

AbstractIntroductionThe COVID‐19 pandemic has resulted in lifestyle changes for children. The aim of this study was to evaluate the impact of the pandemic on weight/BMI in children with severe bleeding disorders.MethodsWe conducted a retrospective review of patients age 3–18 years with severe bleeding disorders on prophylactic therapy treated at SickKids Hospital (Toronto, Canada) between February 01, 2018 and March 31, 2021. We evaluated the following pre‐ and post‐COVID variables: weight (kg), weight percentile, BMI (kg/m2), BMI percentile, HJHS score, and prophylactic dosing (units/kg).ResultsOne hundred and four patients were included in the final analysis. Diagnoses were as follows: haemophilia A (n = 92; 70.8%), haemophilia B (n = 17; 13.1%), type 3 von Willebrand disease (n = 11; 8.5%), the remainder were diagnosed with rare factor deficiencies. Median interval time from pre‐COVID measurements to latest follow‐up was 12.4 months (IQR 10.32–14.52 months) during which there was a statistically significant increase in median weight percentile +5.75 centiles (from 63rdcentile to 68.75thcentile). There was a statistically significant increase in mean BMI of +1.03 kg/m2(P = < .001) while median BMI percentile increased +8.82 centiles (from 53.9thcentile to 62.72ndcentile) and mean BMI percentile increased 3.42 centiles (from 57.5 centile to 60.9 centile). The group that gained the most weight centiles, BMI and BMI centiles were 5–14 years old.ConclusionThere was a trend to weight gain over the study period. More long‐term data is required to evaluate the impact of this increase in weight and BMI on children with bleeding disorders.
Impact of Chitosan‐Prunus cerasoides gum exudates on the thermal properties, storage stability and antioxidant activity of anthocyanins from Berberis lycium Royle
Authors: Sendri Nitisha , Bhatt Vinod , Singh Sarvpreet , Bhandari Pamita 
Published: November 2021

SummaryFor the protection of anthocyanins from berries of Berberis lycium Royle, the freeze dried microencapsulation method was used in five different combinations of chitosan (CH), Prunus cerasoides gum exudate (PG) and galactomannan as wall material with anthocyanin (ANS) as core material. The microencapsulated powders with different proportions of wall material showed encapsulation efficiency in the range of 90.51%–94.60%. Fourier‐transform infrared spectroscopy confirmed the cross‐linking interactions between ANS and wall materials. Enhanced thermal stability of the ANS with wall materials was indicated by thermogravimetric analysis. The stability of microcapsules and ANS was evaluated by spectrophotometric and liquid chromatographic methods at two conditions (4 °C and room temperature) during 90 days. The results revealed that ANS encapsulated with CH‐PG/ANS (4/1) exhibited maximum retention of anthocyanins (72.88% and 60.02%) and enhanced the stability and antioxidant potential of anthocyanins.
First human infection of avian influenza A(H5N6) virus reported in Lao People's Democratic Republic, February–March 2021
Authors: Sengkeopraseuth Bounthanom , Co Kim Carmela , Leuangvilay Phetdavanh , Mott Joshua A. , Khomgsamphanh Boungnasith , Somoulay Virasack , Tsuyuoka Reiko , Chiew May , Ketmayoon Pakapak , Jones Joyce , Pusch Elizabeth , Jang Yunho , Barnes John , Davis Charles Todd , Phommachanh Phouvong , Khamphaphongphane Bouaphanh , Olsen Sonja J. , Xangsayyarath Phonepadith 
Published: November 2021

AbstractIn March 2021, Lao People's Democratic Republic (Laos) reported an avian influenza A(H5N6) virus infection in a 5‐year‐old child identified through sentinel surveillance. This was the first human A(H5N6) infection reported outside of China. A multidisciplinary investigation undertook contact tracing and enhanced human and animal surveillance in surrounding villages and live bird markets. Seven Muscovy ducks tested positive for highly pathogenic avian influenza A(H5N6) viruses. Sequenced viruses belonged to clade 2.3.4.4h and were closely related to viruses detected in poultry in Vietnam and to previous viruses detected in Laos. Surveillance and coordinated outbreak response remain essential to global health security.
Epidemiology, aetiology and knowledge, attitudes, and practices relating to burn injuries in Palestine: A community‐level research
Authors: Abu Ibaid Ali H. , Hebron Caitlin A. , Qaysse Hana'a A. , Coyne Melanie J. , Potokar Tom S. , Shalltoot Fikr A. , Shalabi Mahmoud A. 
Published: November 2021

AbstractThe aim of this study was to identify the epidemiology, aetiology as well as the knowledge, attitudes, and practices relating to burn injuries in Palestine. A mixed‐method approach was used. A survey was distributed to a total of 1500 households selected by randomised approach. The survey was standardised based on World Health Organisation's guidelines for conducting community surveys on injury. Additionally, there were 12 focus group discussions and 10 key informant interviews to collect rich qualitative data. In the West Bank and Gaza, 1.5% of Palestinians had experienced serious burn injuries in the 12 months. The total sample of 1500 yields a margin of error (plus/minus) = 2.5% at a 95% level of confidence and a response distribution (P = 50%) with 3% non‐response rate. Of the 1500 households approached, 184 reported a total of 196 burn injuries, with 87.2% occurring inside the home: 69.4% were females and 39.3% were children. The main source of reported cause of burn was heat and flame (36%), electric current (31.6%), hot liquid (28.6%), and chemicals (2.7%). The most common first aid for burns was pouring water (74.7%). People in rural, refugee, and Bedouin settings had the highest incidence of burns. This study provides the burn prevalence rate, explanatory factors that contribute to the frequency of burns in Palestine. Making burn prevention a higher priority within the national policy is crucial.
What is in a name? Definitions of insomnia in people with intellectual disabilities
Authors: van den Broek Naomi , Festen Dederieke , Tan Francis , Overeem Sebastiaan , Pillen Sigrid 
Published: November 2021

AbstractBackgroundThe reported prevalence of insomnia symptoms in people with intellectual disabilities varies greatly, possibly due to the lack of a common definition. This article provides an overview of the different definitions used and formulates key points for a general definition.MethodsA literature search was performed. An overview of the definitions used was given and compared to the third edition of the international classification of sleep disorders.ResultsThe search yielded 16 studies. No uniform definition was used. Terminology and cut‐off points of insomnia symptoms differed. Insomnia symptoms were mostly described as night‐time problems. A minority of studies incorporated daytime consequences.ConclusionAn insomnia disorder entails more than merely night‐time complaints and should include daytime consequences. A general definition is warranted. This definition should focus on night‐time and daytime insomnia symptoms, incorporate subjective features, and discuss the use of objective measurements and influence of environmental circumstances.
Association between non‐alcoholic fatty liver disease with the susceptibility and outcome of COVID‐19: A retrospective study
Authors: Wang Guyi , Wu Shangjie , Wu Chenfang , Zhang Quan , Wu Fang , Yu Bo , Zhang Siye , Wu Chao , Wu Guobao , Zhong Yanjun 
Published: November 2021

AbstractThis study aims to evaluate the effect of non‐alcoholic fatty liver disease (NAFLD) on the susceptibility and consequences of coronavirus disease 2019 (COVID‐19). We retrospectively collected data from 218 adult COVID‐19 patients who showed no evidence of excessive alcohol consumption and underwent abdominal ultrasound examinations. Of these patients, 39.4% patients had been diagnosed with NAFLD, which indicates a much higher prevalence of NAFLD than that reported in the general population. Significantly elevated white blood cell count (p = 0.008), alanine aminotransferase (p = 0.000), aspartate aminotransferase (p = 0.006) and C reactive protein (p = 0.012) were found in the patients with NAFLD. These patients also had significantly higher proportions of hypertension (p = 0.006) and diabetes (p = 0.049) than the non‐NAFLD cases. No significant differences existed in the severity, mortality, viral shedding time and length of hospital stay between patients with or without NAFLD in the sample population. However, subgroup analyses found that in patients with normal body mass index (BMI), NAFLD sufferers were more likely to experience a severe event (30.0% vs 11.5%, p = 0.021). Kaplan‐Meier curve (log‐rank p = 0.017) and Cox regression (HR = 3.26, 95% CI: 1.17–9.04, p = 0.023) analyses confirmed that before and after adjusting for gender, age and comorbidities, NAFLD patients with normal BMI had a higher incidence of suffering severe events. People with NAFLD may have a higher proportion of COVID‐19. NAFLD may be correlated with the severity of COVID‐19 patients in the normal BMI group.
Efficacy and risks of removable partial prosthesis in periodontitis patients: A systematic review
Authors: Gotfredsen Klaus , Rimborg Susie , Stavropoulos Andreas 
Published: November 2021

AbstractAimThe aim of this systematic review was to answer the following focused question: “In partially edentulous patients with periodontitis, are removable dental prostheses (RDPs) more efficacious than no prosthetic treatment, treatment to a shortened dental arch (SDA), or tooth‐supported fixed dental prostheses (FDPs)?”Materials and methodsA systematic literature search was performed electronically for the period 1966–2020. Two authors independently assessed the studies for eligibility according to the PRISMA guidelines. Risk assessment was performed using RoB 2.0 and the Newcastle–Ottawa Scale.ResultsTwo retrospective studies indicated that RDPs increased the risk of tooth loss compared to FDPs in patients with a history of periodontitis. Prospective studies found that RDPs could be maintained without any significant periodontal destruction on a long‐term basis. Owing to the heterogeneity of the data, no meta‐analysis could be performed. Several studies indicated that RDP increased plaque accumulation. RDPs had only a limited effect on masticatory efficiency and nutritional status. RDPs may improve oral‐health‐related quality of life (OHRQoL), but to a lesser extent compared with that of patients treated to an SDA.ConclusionsThere is no strong evidence that RDPs per se will cause periodontal destruction including tooth loss. RDPs do not inevitably improve masticatory efficiency but improve OHRQoL, although less than for patients treated with FDPs including resin‐bonded FDPs.
Impact of rehabilitation versus edentulism on systemic health and quality of life in patients affected by periodontitis: A systematic review and meta‐analysis
Authors: Gennai Stefano , Izzetti Rossana , Pioli Maria C. , Music Larisa , Graziani Filippo 
Published: November 2021

AbstractAimTo investigate the effect of rehabilitation in fully/partially edentulous patients with stage IV periodontitis on oral‐health‐related quality of life (OHRQoL) and systemic health.Materials and methodsA systematic electronic and manual search was conducted. Three authors independently reviewed, selected, and extracted the data. Outcomes were OHRQoL (Oral Health Impact Profile 14 [OHIP‐14] and OHIP‐49, General Oral Health Assessment Index [GOHAI], visual analogue scale, symptoms registration) and systemic health‐related outcomes (incidence and prevalence of systemic diseases, values of systemic disease indicators). Qualitative data were synthesized for OHRQoL and systemic health‐related outcomes. Meta‐analysis was conducted on available quantitative data.ResultsThe search identified 59 articles (6724 subjects in total). OHRQoL improved across all the studies, irrespective of the number of missing teeth, their location, or treatment modality. Meta‐analysis showed significant improvement of OHIP‐49 (36.86, p < .01) in manuscripts including subjects affected by periodontitis, consistently with the remaining literature (reduction of score points post rehabilitation: OHIP‐14 = 10.52, OHIP‐49 = 56.02, GOHAI = 5.40, p < .01 for all). Non‐rehabilitated subjects exhibited inferior cognitive status, higher medication intake, and frailty. However, our data are limited and should be interpreted with caution.ConclusionsOral rehabilitation improves OHRQoL and, potentially, systemic health in edentulous patients. It is unclear whether these findings may be extrapolated to patients with stage IV periodontitis.
Belonging beyond the binary: from Byzantine eunuchs and Indian hijras to gender‐fluid and non‐binary identities
Authors: GONZALEZ‐SALZBERG DAMIAN A. , PERISANIDI MAROULA 
Published: November 2021

AbstractWhile the majority of Western legal systems continue to insist on the existence of only two genders, a demand for the recognition of non‐binary gender identities has become increasingly visible. Numerous individuals have gone to court demanding recognition of their identities beyond the binary, with varying degrees of success. This article provides a novel lens through which to consider these contemporary legal claims. Through an exploration of historical and cultural examples of gender beyond the binary, more specifically Byzantine eunuchs and Indian hijras, this article analyses the regulatory forces that permit and promote the existence of non‐binary genders. A better understanding of societies that have carved out a space for genders beyond the binary can offer important insights into both the benefits and the dangers of the legal recognition of a third gender.
‘Victims not wrongdoers’: the legal consciousness of rejected asylum seekers in Norway
Authors: HADDELAND HANNA BUER 
Published: November 2021

AbstractDrawing on in‐depth interviews, observation, and legal sources, this article examines how rejected asylum seekers experience their status and the legal regulations related to it, and how they react as a result. Their legal consciousness must be understood in the light of their illegal status, which makes them keenly aware that legal regulations and power structures decisively affect their everyday lives. They are ‘outside the law’ yet struggling to become insiders. While they all use legal services in their individual struggles, their engagement in collective counter‐hegemonic struggles is greatly affected by social relations, networks, and culture. Honneth's theory of recognition is used to expand the narrative of ‘dissenting collectivism’ within legal consciousness scholarship and capture the collective resistance of the marginalized. Unlike studies portraying these migrants as fearful of any involvement with the authorities, this article demonstrates that individual experiences of injustice and violated expectations of recognition can lead to collective resistance and mobilization.
Environmental risk factors for inflammatory bowel disease: A case control study in Southeast Asian children
Authors: Lee Way S , Song Zhi L , Wong Sean Y , Gan Chai W , Koay Zhong L , Em Jun M , Chong Sze Y , Lim Chooi B , Wong Shin Y , Chew Kee S , Kam Choy C 
Published: November 2021

AimEarly‐life environmental exposure, which has important implications in the pathogenesis of inflammatory bowel disease (IBD), is not well understood in Asian children. We examined environmental factors prior to the development of childhood IBD in a Southeast Asian population.MethodsWe conducted a case control study in IBD diagnosed before 18 years of age and controls matched by gender, age and ethnicity. A questionnaire recording medical, family, dietary and social histories, home environment, childhood diseases and immunisation status was used.ResultsIn a multivariate analysis involving 70 children with IBD (Crohn's disease (CD) = 38; ulcerative colitis (UC) = 32) and 140 controls, childhood acute gastroenteritis (odds ratio (OR): IBD 6.9; CD 7.8; UC 5.8) and excessive antibiotic usage in early childhood (OR: IBD 5.3; CD 4.2; UC 4.8) were significantly associated with IBD, CD and UC. Having a fish or turtle aquarium (OR 6.0), major stressful life events (OR 5.6) and attending the same school concurrently with a sibling (OR 2.9) were significant risk factors for IBD. Duration of breastfeeding >6 months (OR: IBD 0.4; UC 0.2) and safe water consumption (OR: IBD 0.2; UC 0.2) reduced the odds of having IBD and UC, respectively. Being vaccinated for rotavirus reduced the odds of developing IBD (OR 0.1).ConclusionsSeveral risk and protective factors were identified in this environmental risk study in Southeast Asian children with IBD. This knowledge has important implications in understanding disease aetiology and future prevention strategies to reduce the development of IBD in Southeast Asian children.
Sleep‐spindle frequency: Overnight dynamics, afternoon nap effects, and possible circadian modulation
Authors: Bódizs Róbert , Horváth Csenge G. , Szalárdy Orsolya , Ujma Péter P. , Simor Péter , Gombos Ferenc , Kovács Ilona , Genzel Lisa , Dresler Martin 
Published: November 2021

SummaryHomeostatic and circadian processes play a pivotal role in determining sleep structure, timing, and quality. In sharp contrast with the wide accessibility of the electroencephalogram (EEG) index of sleep homeostasis, an electrophysiological measure of the circadian modulation of sleep is still unavailable. Evidence suggests that sleep‐spindle frequencies decelerate during biological night. In order to test the feasibility of measuring this marker in common polysomnographic protocols, the Budapest‐Munich database of sleep records (N = 251 healthy subjects, 122 females, age range: 4–69 years), as well as an afternoon nap sleep record database (N = 112 healthy subjects, 30 females, age range: 18–30 years) were analysed by the individual adjustment method of sleep‐spindle analysis. Slow and fast sleep‐spindle frequencies were characterised by U‐shaped overnight dynamics, with highest values in the first and the fourth‐to‐fifth sleep cycle and the lowest values in the middle of the sleeping period (cycles two to three). Age‐related attenuation of sleep‐spindle deceleration was evident. Estimated phases of the nadirs in sleep‐spindle frequencies were advanced in children as compared to other age groups. Additionally, nap sleep spindles were faster than night sleep spindles (0.57 and 0.39 Hz difference for slow and fast types, respectively). The fine frequency resolution analysis of sleep spindles is a feasible method of measuring the assumed circadian modulation of sleep. Moreover, age‐related attenuation of circadian sleep modulation might be measurable by assessing the overnight dynamics in sleep‐spindle frequency. Phase of the minimal sleep‐spindle frequency is a putative biomarker of chronotype.
‘[P]oets unhoused’: Modernism, homelessness and precarity
Authors: Ryan Laura 
Published: November 2021

AbstractIn the past 2 or 3 decades, modernist scholarship has largely moved beyond and certainly challenged the mythologised trope of the alienated, exiled modernist writer. Such figures were generally exiled by choice and ‘homeless’ only metaphorically, but their experiences have long been lauded as the ideal conditions for modernist formal innovations. This essay explores the ways in which issues of homelessness and precarity have been considered thus far in modernist scholarship, arguing that more work is needed to account for the particular experiences of writers I here call the ‘homeless modernists’ and the impact of unstable housing upon modernist aesthetics and themes.
Building Community Through Ethnography in Action to Catalyze Student, Faculty, and Community Collaborations
Authors: McCormack Penske , Johns Zoi , Neiss Kassandra , Kinyon Kamila , Cerón Alejandro 
Published: November 2021

AbstractSince its initial conception in 2017, the University of Denver Ethnography Lab (DUEL) has aimed to catalyze collaborations between students, faculty, and community organizations. Inspired by community–campus partnerships implemented in the past across the United States, DUEL seeks to cultivate a community of practice centered on ethnography in action, and to draw on strengths and opportunities specific to our university. In this article, we present the process that channeled the energies and ideas of 30 faculty and students from 10 different departments into the creation of DUEL, we share examples from our experience so far, and we identify challenges and opportunities for DUEL's future.
Nursing students' experience of providing frontline COVID‐19 support: A qualitative study
Authors: Vázquez‐Calatayud Mónica , Rumeu‐Casares Carmen , Olano‐Lizarraga Maddi , Regaira Martínez Elena 
Published: November 2021

AbstractUnderstanding the unique experience of nursing students providing frontline support in COVID‐19 hospital wards is crucial for the design of strategies to improve crisis management and mitigate future pandemic outbreaks. Limited research concerning this phenomenon has been published. This qualitative study aimed to understand the experience of providing support from COVID‐19 frontline nursing students' perspective. Online interviews were conducted with nine nursing students from April to May 2020; interview data were analyzed by content analysis using Burnard's method. Six main categories emerged from the data analysis: “experiencing a rapid transition from student to professional,” “fear and uncertainty of the unknown,” “resilience throughout the crisis,” “sense of belonging to a team,” “shared responsibility,” and “importance of the profession.” Based on these findings, multicomponent strategies that function in parallel with practical contexts should be developed to enable students to diligently adapt their abilities to their new role and cope with health crises.