bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antithrombotic therapy in high-risk patients after percutaneous coronary intervention; study design, cohort profile and incidence of adverse events
Authors: Olie R. H. , van der Meijden P. E. J. , Vries M. J. A. , Veenstra L. , van ‘t Hof A. W. J. , ten Berg J. M. , Henskens Y. M. C. , ten Cate H. 
Published: September 2021

Abstract
Background
Patients with multiple clinical risk factors are a complex group in whom both bleeding and recurrent ischaemic events often occur during treatment with dual/triple antithrombotic therapy after percutaneous coronary intervention. Decisions on optimal antithrombotic treatment in these patients are challenging and not supported by clear guideline recommendations. A prospective observational cohort study was set up to evaluate patient-related factors, platelet reactivity, genetics, and a broad spectrum of biomarkers in predicting adverse events in these high-risk patients. Aim of the current paper is to present the study design, with a detailed description of the cohort as a whole, and evaluation of bleeding and ischaemic outcomes during follow-up, thereby facilitating future research questions focusing on specific data provided by the cohort.

Methods
We included patients with ≥ 3 predefined risk factors who were treated with dual/triple antithrombotic therapy following PCI. We performed a wide range of haemostatic tests and collected all ischaemic and bleeding events during 6–12 months follow-up.

Results
We included 524 high-risk patients who underwent PCI within the previous 1–2 months. All patients used a P2Y12 inhibitor (clopidogrel n = 388, prasugrel n = 61, ticagrelor n = 75) in combination with aspirin (n = 397) and/or anticoagulants (n = 160). Bleeding events were reported by 254 patients (48.5%), necessitating intervention or hospital admission in 92 patients (17.5%). Major adverse cardiovascular events (myocardial infarction, stroke, death) occurred in 69 patients (13.2%).

Conclusion
The high risk for both bleeding and ischaemic events in this cohort of patients with multiple clinical risk factors illustrates the challenges that the cardiologist faces to make a balanced decision on the optimal treatment strategy. This cohort will serve to answer several future research questions about the optimal management of these patients on dual/triple antithrombotic therapy, and the possible value of a wide range of laboratory tests to guide these decisions.
Stochastic-based liquid apparent permeability model of shale oil reservoir considering geological control
Authors: Xu Jilong , Wang Wendong , Ma Bing , Su Yuliang , Wang Han , Zhan Shiyuan 
Published: September 2021

AbstractShale is a complex porous medium composed of organic matter (OM) and inorganic minerals (iOM). Because of its widespread nanopores, using Darcy’s law is challenging. In this work, a two-fluid system model is established to calculate the oil flow rate in a single nanopore. Then, a spatial distribution model of shale components is constructed with a modified quartet structure generation set algorithm. The stochastic apparent permeability (AP) model of shale oil is finally established by combining the two models. The proposed model can consider the effects of various geological controls: the content and grain size distribution of shale components, pore size distribution, pore types and nanoconfined effects (slip length and spatially varying viscosity). The results show that slip length in OM nanopores is far greater than that in iOM. However, when the total organic content is less than 0.3 ~ 0.4, the effect of the OM slip on AP increases first and then decreases with the decrease in mean pore size, resulting in that the flow enhancement in shale is much smaller than that in a single nanopore. The porosity distribution and grain size distribution are also key factors affecting AP. If we ignore the difference of porosity between shale components, the error of permeability estimation is more than 200%. Similarly, the relative error can reach 20% if the effect of grain size distribution is ignored. Our model can help understand oil transport in shale strata and provide parameter characterization for numerical simulation.
Thoughts that breathe, and words that burn: poetic inquiry within health professions education
Authors: Brown Megan E. L. , Kelly Martina , Finn Gabrielle M. 
Published: September 2021

Qualitative inquiry is increasingly popular in health professions education, and there has been a move to solidify processes of analysis to demystify the practice and increase rigour. Whilst important, being bound too heavily by methodological processes potentially represses the imaginative creativity of qualitative expression and interpretation—traditional cornerstones of the approach. Rigid adherence to analytic steps risks leaving no time or space for moments of ‘wonder’ or emotional responses which facilitate rich engagement. Poetic inquiry, defined as research which uses poetry ‘as, in, [or] for inquiry’, offers ways to encourage creativity and deep engagement with qualitative data within health professions education. Poetic inquiry attends carefully to participant language, can deepen researcher reflexivity, may increase the emotive impact of research, and promotes an efficiency of qualitative expression through the use of ‘razor sharp’ language. This A Qualitative Space paper introduces the approach by outlining how it may be applied to inquiry within health professions education. Approaches to engaging with poetic inquiry are discussed and illustrated using examples from the field’s scholarship. Finally, recommendations for interested researchers on how to engage with poetic inquiry are made, including suggestions as to how to poetize existing qualitative research practices.
„NGOisierung“ der Interessenvermittlung und Pluralisierung der Politikgestaltung
Authors: Thierse Stefan , Schiffers Maximilian 
Published: September 2021

ZusammenfassungDer einführende Beitrag dieses Special Issue widmet sich dem wechselseitigen Verhältnis von Veränderungsprozessen der Interessenvermittlung und dem Funktionswandel von Nichtregierungsorganisationen (NGOs). Unter Bezugnahme auf das Konzept der NGOisierung werden organisationale und strategische Anpassungen umrissen, die den veränderten institutionellen Rahmenbedingungen von Interessenvermittlung und Politikgestaltung Rechnung tragen und die nicht allein auf NGOs begrenzt sind. Der Wandel einzelner NGOs und des Systems der NGOs als Ganzem lässt sich entlang von zwei Funktionen untersuchen: die öffentlichkeitswirksame, kritische Anwaltschaft für Anliegen strukturell schwacher Interessen einerseits und die Mitwirkungen an der Aushandlung, Implementation und Überwachung regulativer Standards andererseits. Diese beiden Funktionen und die damit verbundenen Zielkonflikt bilden den analytischen Rahmen für die nachfolgenden Beiträge, die kurz und bündig vorgestellt werden. Außerdem werden über die in dem Special Issue vereinten Beiträge hinausweisende Forschungsdesiderate skizziert.
Improvements in Sleep Quality and Duration Following a Meditation Retreat: an Open-Trial Pilot Study
Authors: Kanchibhotla Divya , Parekh Sheel Galada , Harsora Prateek , Kulkarni Shashank 
Published: September 2021

Abstract
Purpose
Disturbed sleep and other sleep-related problems have a negative impact on the human mind and body. Meditation practices are reported to improve physiological functions and might also have a positive impact on regulating sleep. This research investigates the efficacy of an advanced mind–body medicine intervention, called Hollow and Empty Meditation (HEM), on improving sleep quality.

Methods
The study was a single-arm open-trial pilot study which assessed 413 adults who underwent a 4-day meditation retreat offered by the Art of Living, called the Advanced Meditation Program (AMP), and experienced a novel meditation—HEM. Results were measured using a self-report questionnaire, the Pittsburgh Sleep Quality Index (PSQI), which was administered to the participants thrice: on the first day of the program (pre-intervention), immediately after program (post-intervention/Day 4), and on Day 40 (D40) after the program.

Results
There was a significant difference in pre–post and pre–D40 scores in the population. Both sleep quality and sleep duration showed an improvement immediately after the AMP (post), and the residual impact was still experienced at D40, especially with the group with age > 36 years.

Conclusions
The use of HEM resulted in improvement in sleep quality not just immediately after the program, but had longer-term effects that extended over several weeks, helping remediate sleep problems among younger adults as well as older ones. It resulted in improvement in sleep quality as well as reduction in sleep-related daytime impairment, which have substantial constructive implications for well-being, everyday functioning and quality of life.
De-centering the Revolution: Class Composition in the Making and Defeat of the Bavarian Council Republic
Authors: Schaupp Simon 
Published: September 2021

AbstractIn November 1918, the labor movement of Bavaria, Germany, overthrew the monarchist government and, in April 1919, proclaimed a Bavarian Council Republic (BCR). This article analyzes the revolution and its defeat through the lens of class composition theory, thereby suggesting some revisions to the latter. The technical composition of the Bavarian working class fostered the concept of self-management, which lay at the heart of the councils as the organizational form of the revolution. However, it also nurtured authoritarian potentials, which were more in line with-counter revolutionary positions. The article suggests that class composition theory must be expanded by the notion of social composition, taking into account struggles over reproduction and consumption: Inflation, unemployment, food shortages, and disease led to a crisis in material reproduction, which in turn led large parts of the unemployed and of the women's movement to become radical revolutionaries. The article argues to conceptualize technical and social class composition to be in a dialectical relationship with political composition. It thus emphasizes the role of ideologies of anti-Semitism and anti-feminism, both within the counter-revolution and the revolution itself. While the combination of different struggles for emancipation contributed to the early successes of the revolution, their ideological division was as an important factor in its defeat.
Le ne de négation dans Marius de Marcel Pagnol : pièce de théâtre (1929), film (1931) et remake (2013)
Authors: Courdès-Murphy Léa , Jansen Luise 
Published: September 2021

RÉSUMÉDifférentes études suggèrent que le ne de négation se perd de plus en plus en français parlé (cf. Ashby, 2001 ; Armstrong et Smith, 2002 ; Hansen et Malderez, 2004). Notre travail pose la question de savoir si un tel développement peut également être observé dans l’oral mis en scène. Nous analysons pour ce faire le changement du langage mis en scène au fil du temps ainsi que le changement médial entre le drame écrit et son adaptation. Notre corpus se compose du drame Marius (1929) de Marcel Pagnol, du film Marius (1931) d’Alexander Korda et du remake Marius de Daniel Auteuil (2013). Nous avons analysé ce corpus selon l’approche classique de la sociolinguistique, en considérant le ne de négation comme variable sociolinguistique (cf. Labov, 1972). Nos résultats montrent que l’oral mis en scène dans le drame se distingue nettement de la façon dont parlent les personnages dans les films, puisque le ne y figure bien plus souvent. Par ailleurs, le nombre bien plus élevé de ne dans le remake de 2013 que dans la version de 1931 pourrait être une stratégie mise en place pour représenter de l’oral ancien.
L’oralité mise en scène: syntaxe et phonologie – introduction
Authors: Pustka Elissa , Dufter Andreas , Hornsby David 
Published: September 2021

La linguistique prétend s’intéresser en priorité à l’oral – or, elle a pendant longtemps en majorité étudié de l’écrit. Cela s’explique tout d’abord par des contraintes techniques: avant l’invention du phonographe en 1877, nous n’avons aucun accès direct à l’oral. Même de nos jours, le recueil d’enregistrements oraux reste encore trop rare; la construction et analyse de grands corpus sont coûteuses. Dans une perspective historique, il est bien évidemment très difficile de reconstruire l’oral à partir de l’écrit. Se pose cependant la question du statut de ces données: à quel point s’agit-il d’un oral « imité », « imaginé » ou même « manipulé » ?
Alternating Fixpoint Operator for Hybrid MKNF Knowledge Bases as an Approximator of AFT
Authors: LIU FANGFANG , YOU JIA-HUAI 
Published: September 2021

AbstractApproximation fixpoint theory (AFT) provides an algebraic framework for the study of fixpoints of operators on bilattices and has found its applications in characterizing semantics for various classes of logic programs and nonmonotonic languages. In this paper, we show one more application of this kind: the alternating fixpoint operator by Knorr et al. for the study of the well-founded semantics for hybrid minimal knowledge and negation as failure (MKNF) knowledge bases is in fact an approximator of AFT in disguise, which, thanks to the abstraction power of AFT, characterizes not only the well-founded semantics but also two-valued as well as three-valued semantics for hybrid MKNF knowledge bases. Furthermore, we show an improved approximator for these knowledge bases, of which the least stable fixpoint is information richer than the one formulated from Knorr et al.’s construction. This leads to an improved computation for the well-founded semantics. This work is built on an extension of AFT that supports consistent as well as inconsistent pairs in the induced product bilattice, to deal with inconsistencies that arise in the context of hybrid MKNF knowledge bases. This part of the work can be considered generalizing the original AFT from symmetric approximators to arbitrary approximators.
From Bushfires to Misfires: Climate-related Financial Risk after McVeigh v. Retail Employees Superannuation Trust
Authors: Colombo Esmeralda 
Published: September 2021

AbstractThe year 2020 proved to be a clarion call for global society. There is no longer doubt that increasingly we are experiencing unpredictable events, known as ‘black swans’, ranging from pandemics to financial meltdowns. One of the ’climate black swans’ against which experts have cautioned is the financial crisis caused by climate change. In this context, the Australian case of McVeigh v. Retail Employees Superannuation Trust for the first time tested climate risk and the fiduciary duties of retail pension funds. Settled in November 2020, the case has already raised the bar for climate risk practice in pension funds. In particular, McVeigh suggests that courts, as well as out-of-court settlements, may articulate a duty, rather than grant permission, for pension funds to consider climate-related financial risk in their investment decisions.The article builds on McVeigh to ask two questions. Firstly, what is the role of climate change litigation in promoting climate regulation by pension funds? Secondly, what is the relative importance of pension funds for the risk management of climate-related financial risk via due diligence compared with risk assessment via disclosure? Fundamentally, the article explains climate-related financial risk as a cultural phenomenon and argues that a discussion on pension fund fiduciary duties must consider disclosure in addition to due diligence. It argues that McVeigh articulated the need for a normative approach to pension fund disclosure duties and an extension of the field of climate-related risk disclosure to embrace climate-related risk due diligence.
The Structure of the Martian Quasi‐Perpendicular Supercritical Shock as Seen by MAVEN
Authors: Burne S. , Bertucci C. , Mazelle C. , Morales L. F. , Meziane K. , Halekas J. , Fowler C. M. , Espley J. , Mitchell D. , Penou E. 
Published: September 2021

AbstractThe Martian bow shock is a rich example of a supercritical, mass‐loaded collisionless shock that coexists with ultra‐low frequency upstream waves that are generated by the pick‐up of exospheric ions. The small size of the bow shock stand‐off distance (comparable with the solar wind ion convective gyroradius) raises questions about the nature of the particle acceleration and energy dissipation mechanism at work. The study of the Martian shock structure is crucial to understand its microphysics and is of special interest to understand the solar wind—planet interaction with a virtually unmagnetized body. We report on a complete identification and first characterization of the supercritical substructures of the Martian quasi‐perpendicular shock, under the assumption of a moving shock layer, using MAVEN magnetic field and solar wind plasma observations for two examples of shock crossings. We obtained substructures length‐scales comparable to those of the Terrestrial shock, with a narrow shock ramp of the order of a few electron inertial lengths. We also observed a well defined foot (smaller than the proton convected gyroradius) and overshoot that confirm the importance of ion dynamics for dissipative effects.
Detecting Climate Teleconnections With Granger Causality
Authors: Silva Filipi N. , Vega‐Oliveros Didier A. , Yan Xiaoran , Flammini Alessandro , Menczer Filippo , Radicchi Filippo , Kravitz Ben , Fortunato Santo 
Published: September 2021

AbstractClimate system teleconnections are crucial for improving climate predictability, but difficult to quantify. Standard approaches to identify teleconnections are often based on correlations between time series. Here we present a novel method leveraging Granger causality, which can infer/detect relationships between any two fields. We compare teleconnections identified by correlation and Granger causality at different timescales. We find that both Granger causality and correlation consistently recover known seasonal precipitation responses to the sea surface temperature pattern associated with the El Niño Southern Oscillation. Such findings are robust across multiple time resolutions. In addition, we identify candidates for unexplored teleconnection responses.
Observational Evidence of Transient Lobe Reconnection Triggered by Sudden Northern Enhancement of IMF Bz
Authors: Wang Zhiwei , Hu Hongqiao , Lu Jianyong , Han Desheng , Liu Jianjun , Wu Yewen , Hu Zejun 
Published: September 2021

AbstractIn general, lobe reconnection occurs under northward interplanetary magnetic field (IMF) Bz. However, what process can trigger lobe reconnection has not been fully understood. Using observations from SuperDARN radar and Defense Meteorological Satellite Program (DMSP) spacecraft, we found that (a) short‐term sunward ionospheric flow bursts observed by SuperDARN poleward of the cusp showed one‐to‐one correspondent with the sudden increase of the IMF Bz, (b) the sunward flow bursts observed by SurperDARN were associated with sunward ion drifts identified from the DMSP satellite, and (c) a cusp auroral spot, together with an inverse ion energy dispersion, was observed in association with one of the flow bursts. We suggest that these observations provide evidence that the lobe reconnections can be triggered by a sudden increase of the IMF Bz component. What’s more, we found that the reconnection signatures disappeared quickly after the IMF Bz enhancement being over, which indicates that the lobe reconnection triggered by the sudden increase of the IMF Bz is a transient process.
Aquatic‐Terrestrial Linkages Control Metabolism and Carbon Dynamics in a Mid‐Sized, Urban Stream Influenced by Snowmelt
Authors: Reed A. P. , Stets E. G. , Murphy S. F. , Mullins E. A. 
Published: September 2021

AbstractFreshwater streams can exchange nutrients and carbon with the surrounding terrestrial environment through various mechanisms including physical erosion, flooding, leaf drop, and snowmelt. These aquatic‐terrestrial interactions are crucial in carbon mobilization, transformation, ecosystem productivity, and have important implications for the role of freshwater ecosystems in the global carbon budget. We utilized high‐frequency oxygen, temperature, and carbon dioxide (CO2) data to infer watershed connectivity in Boulder Creek, a mid‐sized (1160 km2) watershed located in Colorado, USA. Daily modeled gross primary production (GPP), ecosystem respiration (ER), net ecosystem production (NEP), and reaeration coefficients (K600) were paired with high‐frequency, in‐situ dissolved CO2 data to characterize changes in metabolic regime and carbon flux on a stream influenced by seasonal snowmelt. GPP and ER were correlated (ρ = −0.72, p ≪ 0.001) during the non‐snowmelt period and NEP was frequently negative. Mean FCO2 during the non‐snowmelt period was approximately 302 (±171) mmol C m−2 d−1 and was primarily supported by watershed CO2 inputs. During snowmelt, GPP and ER were not significantly correlated (ρ = −0.22, p = 0.05), and mean NEP was significantly more negative than during non‐snowmelt. Watershed connectivity was higher during snowmelt, as evidenced by significantly higher FCO2 (843 ± 338 mmol C m−2 d−1) and greater allochthonous CO2 inputs than during non‐snowmelt periods, emphasizing the effects of seasonal differences in aquatic‐terrestrial linkages in this stream. We suggest that our understanding of watershed carbon budgets is subject to temporal dynamics which control the degree of connectivity between terrestrial and aquatic ecosystems.
Metabolomic changes in animal models of depression: a systematic analysis
Authors: Pu Juncai , Liu Yiyun , Gui Siwen , Tian Lu , Yu Yue , Song Xuemian , Zhong Xiaogang , Chen Xiaopeng , Chen Weiyi , Zheng Peng , Zhang Hanping , Gong Xue , Liu Lanxiang , Wu Jing , Wang Haiyang , Xie Peng 
Published: September 2021

AbstractExtensive research has been carried out on the metabolomic changes in animal models of depression; however, there is no general agreement about which metabolites exhibit constant changes. Therefore, the aim of this study was to identify consistently altered metabolites in large-scale metabolomics studies of depression models. We performed vote counting analyses to identify consistently upregulated or downregulated metabolites in the brain, blood, and urine of animal models of depression based on 3743 differential metabolites from 241 animal metabolomics studies. We found that serotonin, dopamine, gamma-aminobutyric acid, norepinephrine, N-acetyl-L-aspartic acid, anandamide, and tryptophan were downregulated in the brain, while kynurenine, myo-inositol, hydroxykynurenine, and the kynurenine to tryptophan ratio were upregulated. Regarding blood metabolites, tryptophan, leucine, tyrosine, valine, trimethylamine N-oxide, proline, oleamide, pyruvic acid, and serotonin were downregulated, while N-acetyl glycoprotein, corticosterone, and glutamine were upregulated. Moreover, citric acid, oxoglutaric acid, proline, tryptophan, creatine, betaine, L-dopa, palmitic acid, and pimelic acid were downregulated, and hippuric acid was upregulated in urine. We also identified consistently altered metabolites in the hippocampus, prefrontal cortex, serum, and plasma. These findings suggested that metabolomic changes in depression models are characterized by decreased neurotransmitter and increased kynurenine metabolite levels in the brain, decreased amino acid and increased corticosterone levels in blood, and imbalanced energy metabolism and microbial metabolites in urine. This study contributes to existing knowledge of metabolomic changes in depression and revealed that the reproducibility of candidate metabolites was inadequate in previous studies.