bluuebunny/crossref_metadata_2025_split huggingface dataset:
How preceptors develop trust in continuity clinic residents and how trust influences supervision: A&nbsp;qualitative study
Authors: Penner John C. , Hauer Karen E. , Julian Katherine A. , Sheu Leslie 
Published: December 2021

Introduction To advance in their clinical roles, residents must earn supervisors’ trust. Research on supervisor trust in the inpatient setting has identified learner, supervisor, relationship, context, and task factors that influence trust. However, trust in the continuity clinic setting, where resident roles, relationships, and context differ, is not well understood. We aimed to explore how preceptors in the continuity clinic setting develop trust in internal medicine residents and how trust influences supervision.
Methods In this qualitative study, we conducted semi-structured interviews with faculty preceptors from two continuity clinic sites in an internal medicine residency program at an urban academic medical center in the United States from August 2018–June 2020. We analyzed transcripts using thematic analysis with sensitizing concepts related to the theoretical framework of the five factors of trust.
Results Sixteen preceptors participated. We identified four key drivers of trust and supervision in the continuity clinic setting: 1) longitudinal resident-preceptor-patient relationships, 2) direct observations of continuity clinic skills, 3) resident attitude towards their primary care physician role, and 4) challenging context and task factors influencing supervision. Preceptors shared challenges to determining trust stemming from incomplete knowledge about patients and limited opportunities to directly observe and supervise between-visit care.
Discussion The continuity clinic setting offers unique supports and challenges to trust development and trust-supervision alignment. Maximizing resident-preceptor-patient continuity, promoting direct observation, and improving preceptor supervision of residents’ provision of between-visit care may improve resident continuity clinic learning and patient care.
Two Constitutional Cultures, Technological Enforcement and User Creativity: The Impending Collapse of the EU Copyright Regime?
Authors: Westkamp Guido 
Published: December 2021

AbstractInPelham, the Court of Justice of the European Union and the German Federal Constitutional Court reached diametrically opposing conclusions on the relevance of freedom of art in copyright law. The different stances permit a speculative prediction – they can have immediate consequences for the predictable challenges against the new platform liability regime, and its associated dangers of widespread filtering and blocking. The article discusses the numerous constitutional implications, with specific attention given to the respective interests affected by the new regime (authors, exploiters, users, platforms) in light of the divergent approaches from the perspective of what appears to be two rather conflicting constitutional cultures: specific perceptions of fundamental rights and proportionality under German law versus an approach tending to emphasise market integration under the EU legal order. Recent assertions by the German Federal Constitutional Court redistributing the division of competences between national and EU law permit the prediction of a disturbing future collision course between the two systems, with potentially massive implications for EU copyright law by and large.
Unlocking the bacterial contact-dependent antibacterial activity to engineer a biocontrol alliance of two species from natural incompatibility to artificial compatibility
Authors: Wu Qianhua , Wang Bozhen , Shen Xi , Shen Danyu , Wang Bingxin , Guo Qinggang , Li Tao , Shao Xiaolong , Qian Guoliang 
Published: December 2021

AbstractPlant growth-promoting rhizobacteria (PGPR) contain various biocontrol bacteria with broad-spectrum antimicrobial activity, and their single species has been extensively applied to control crop diseases. The development of complex biocontrol community by mixing two or more PGPR members together is a promising strategy to enlarge the efficacy and scope of biocontrol. However, an effective method to assess the natural compatibility of PGPR members has not yet been established to date. Here, we developed such a tool by using the bacterial contact-dependent antibacterial activity (CDAA) as a probe. We showed that the CDAA events are common in two-species interactions in the four selected representative PGPRs, represented by the incompatible interaction of Lysobacter enzymogenes strain OH11 (OH11) and Lysobacter antibioticus strain OH13 (OH13). We further showed that the CDAA between OH11 and OH13 is jointly controlled by a contact-dependent killing device, called the type IV secretion system (T4SS). By deleting the respective T4SS synthesis genes, the T4SS in both strains was co-inactivated and this step unlocked their natural CDAA, resulting in an engineered, compatible mutant alliance that co-displayed antibacterial and antifungal activity. Therefore, this study reveals that releasing bacterial CDAA is effective to rationally engineer the biocontrol community.
A Proposed Method to Evaluate Warehouse Location for 3PL Cold Chain Suppliers in Gulf Countries Using Neutrosophic Fuzzy EDAS
Authors: Demircan Murat Levent , Özcan Berkay 
Published: December 2021

AbstractLogistics processes have been analyzed as one of the most critical expense items for companies. Companies that failed to manage their logistics processes well could not reach the desired growth rates, and some even disappeared. Logistics management without process optimizations can be time and money consuming for the companies. Logistics processes significantly influence organizations' efficiency. Logistic professionals should keep the process flow quality at a certain level, and some decision problems should be analyzed and answered well. Location selection of a warehouse is one of the most crucial decision problems of supply chain and logistics management. Alternatives are evaluated in quantitative and qualitative criteria to decide the best location alternative using scientific MCDM techniques. Different scientific methods have been developed and used to solve this problem. As for this study, the aim is to investigate the warehouse location selection of third-party cold chain logistics suppliers. The importance of keeping perishable products under the right conditions increased, since it is realized that cold chain warehousing and transportation prevent the product spoiled. Organizations can save their funds and time by having effective cold chain management. This study's main scope is to give a new scientific perspective for warehouse selection in cold chain logistics. MCDM technique of Interval-Valued Neutrosophic Fuzzy (IVNF) EDAS method has been used to evaluate essential criteria and choose the best option. Critical cities of Gulf Region countries have been considered alternatives in a numerical illustration.
Re-examination of species limits in Aspergillus section Flavipedes using advanced species delimitation methods and description of four new species
Authors: Jurjević Ž. , Houbraken J. , Sklenář F. , Kolařík M. , Arendrup M.C. , Jørgensen K.M. , Siqueira J.P.Z. , Gené J. , Yaguchi T. , Ezekiel C.N. , Silva Pereira C. , Hubka V. 
Published: December 2021

Since the last revision in 2015, the taxonomy of section Flavipedes evolved rapidly along with the availability of new species delimitation techniques. This study aims to re-evaluate the species boundaries of section Flavipedes members using modern delimitation methods
applied to an extended set of strains (n = 90) collected from various environments. The analysis used DNA sequences of three house-keeping genes (benA, CaM, RPB2) and consisted of two steps: application of several single-locus (GMYC, bGMYC, PTP, bPTP) and multi-locus (STACEY)
species delimitation methods to sort the isolates into putative species, which were subsequently validated using DELINEATE software that was applied for the first time in fungal taxonomy. As a result, four new species are introduced, i.e. A. alboluteus, A. alboviridis,
A. inusitatus and A. lanuginosus, and A. capensis is synonymized with A. iizukae. Phenotypic analyses were performed for the new species and their relatives, and the results showed that the growth parameters at different temperatures and colonies
characteristics were useful for differentiation of these taxa. The revised section harbors 18 species, most of them are known from soil. However, the most common species from the section are ecologically diverse, occurring in the indoor environment (six species), clinical samples (five species),
food and feed (four species), droppings (four species) and other less common substrates/environments. Due to the occurrence of section Flavipedes species in the clinical material/hospital environment, we also evaluated the susceptibility of 67 strains to six antifungals (amphotericin
B, itraconazole, posaconazole, voriconazole, isavuconazole, terbinafine) using the reference EUCAST method. These results showed some potentially clinically relevant differences in susceptibility between species. For example, MICs higher than those observed for A. fumigatus wild-type
were found for both triazoles and amphotericin B for A. ardalensis, A. iizukae, and A. spelaeus whereas A. lanuginosus, A. luppiae, A. movilensis, A. neoflavipes, A. olivimuriae and A. suttoniae were comparable to or more susceptible as A. fumigatus.
Finally, terbinafine was in vitro active against all species except A. alboviridis.
Analysis and optimisation design on damping orifice of oleo-pneumatic landing gear
Authors: Gan S. , Fang X. , Wei X. 
Published: December 2021

AbstractThis paper investigates the feasibility of improving the aircraft landing performance by design the damping orifice parameters of the landing gear using lattice Boltzmann method coupled with the response surface method. The LBM is utilised to simulate characteristics of the damping orifice after model validation. The numerical model of the landing gear using simulated damping force is validated by single landing gear drop test. Based on the numerical model and the response surface functions, the sensitivity analysis and the optimisation design are performed. The maximum error of mean velocity simulated using LBM with experimental data is 7.07% for sharp-edged orifices. Moreover, the numerical model predicts the landing responses adequately, the maximum error with drop test data is 2.51%. The max overloading of the aircraft decreases by 5.44% after optimisation, which proves that this method is feasible to design the damping orifice for good landing performance.
Concentration of selected elements in the hair of Madagascar girls in relation to nutritional status and place of residence
Authors: Zielińska-Dawidziak Magdalena , Czlapka-Matyasik Magdalena , Wojciechowska Zofia , Proch Jędrzej , Niedzielski Przemysław 
Published: December 2021

AbstractAlthough the children malnutrition in Madagascar and the environmental pollution of this country has been widely discussed, there is no research on the differences in toxic elements accumulation in human body in dependence on nutritional status of Malagasy. Nine elements concentration (Al, As, Cd, Cr, Hg, Ni, Pb, Sn and Sb) was determined in scalp hair of 103 schoolgirls (8–15 years old), living in two areas: urban – close to Antananarivo (UR) and rural Berevo region (RU). Samples were analysed by an inductively coupled plasma optical emission spectrometer. The nutritional status was evaluated by Cole’s index. Underweight was related to higher accumulation of Al, Cd and Cr in the hair girls, and more common among girls living in RU than UR region (42 %v. 28 %). Two-factor ANOVA showed differences in the Al and Cr content in the girls’ hair depending both on their place of residence and nutritional status. This indicates additional consequence of malnutrition to the girls development and health.
Unlawful Occupiers, Eviction and the National State of Disaster: Considering South Africa's Emergency Legislation and Jurisprudence During COVID-19
Authors: Dube Felix , du Plessis Anél 
Published: December 2021

AbstractThis article analyses how emergency regulations protected persons living in urban poverty, particularly unlawful occupiers, from eviction during the COVID-19 pandemic in South Africa. It is set against the socio-economic and environmental effects of unlawful occupiers being forced onto the streets through evictions. It examines the judicial interpretation and application of the COVID-19 regulations on the prohibition of the eviction of unlawful occupiers, together with remedies for compensation for demolished dwellings. Ultimately, the article shows that the regulatory and judicial responses to the pandemic were pro-poor and sought to protect human dignity, the right to life, and the right to an environment that is not detrimental to human health and well-being. The responses safeguarded access to housing at a time when many vulnerable people could have been rendered homeless by eviction and the demolition of their dwellings.
Coercing Mobility: Territory and Displacement in the Politics of Southeast Asian Muslim Movements
Authors: Gedacht Joshua , Malhi Amrita 
Published: December 2021

AbstractThis introductory article explores the recent turn in Asian history towards work that foregrounds mobility, circulation, and cosmopolitan connections, decentring colonial territoriality and postcolonial geo-bodies as the primary units of historical analysis. In it, and to frame our own special issue on Muslim movements in Southeast Asia, we point out that some of this mobility was coerced via projects of state territorialisation that actively displaced select, targeted Muslim actors whose presence in the polity was deemed problematic by states seeking to consolidate their power. Echoes of this displacement can be traced in the politics of the Muslim movements that these actors created, as we argue in this article and throughout the special issue.
“Motorcycle Ambulance” Policy to Promote Health and Sustainable Development in Large Cities
Authors: Apiratwarakul Korakot , Suzuki Takaaki , Celebi Ismet , Tiamkao Somsak , Bhudhisawasdi Vajarabhongsa , Pearkao Chatkhane , Ienghong Kamonwon 
Published: December 2021

AbstractIntroduction:Motorcycles can be considered a new form of smart vehicle when taking into account their small and modern structure and due to the fact that nowadays, they are used in the new role of ambulance to rapidly reach emergency patients in large cities with traffic congestion. However, there is no study regarding the measuring of access time for motorcycle ambulances (motorlances) in large cities of Thailand.Study Objective:This study aims to compare access times to patients between motorlances and conventional ambulances, including analysis of the use of automated external defibrillators (AEDs) installed on motorlances to contribute to the sustainable development of public health policies.Methods:A cross-sectional study was conducted on all motorlance operations in Emergency Medical Services (EMS) at Srinagarind Hospital, Thailand from January 2019 through December 2020. Data were recorded using a national standard operation record form for Thailand.Results:Two hundred seventy-one motorlance operations were examined over a two-year period. A total of 52.4% (N = 142) of the patients were male. The average times from dispatch to vehicle (motorlance and traditional ambulance) being en route (activation time) for motorlance and ambulance in afternoon shift were 0.59 minutes and 1.45 minutes, respectively (P = .004). The average motorlance response time in the afternoon shift was 6.12 minutes, and ambulance response time was 9.10 minutes at the same shift. Almost all of the motorlance operations (97.8%) were found to have no access to AED equipment installed in public areas. The average time from dispatch to AED arrival on scene (AED access time) was 5.02 minutes.Conclusion:The response time of motorlances was shorter than a conventional ambulance, and the use of AEDs on a motorlance can increase the chances of survival for patients with cardiac arrest outside the hospital in public places where AEDs are not available.
Genome-wide DNA methylation profiling in nonagenarians suggests an effect of PM20D1 in late onset Alzheimer’s disease
Authors: Coto-Vílchez Carolina , Martínez-Magaña José J. , Mora-Villalobos Lara , Valerio Daniel , Genis-Mendoza Alma D. , Silverman Jeremy M. , Nicolini Humberto , Raventós Henriette , Chavarria-Soley Gabriela 
Published: December 2021

AbstractBackgroundThe aim of this study is to identify differentially methylated regions (DMRs) in the genomes of a sample of cognitively healthy individuals and a sample of individuals with LOAD, all of them nonagenarians from Costa Rica.MethodsIn this study, we compared whole blood DNA methylation profiles of 32 individuals: 21 cognitively healthy and 11 with LOAD, using the Infinium MethylationEPIC BeadChip. First, we calculated the epigenetic age of the participants based on Horvath’s epigenetic clock. DMRcate and Bumphunter were used to identify DMRs. After in silico and knowledge-based filtering of the DMRs, we performed a methylation quantitative loci (mQTL) analysis (rs708727 and rs960603).ResultsOn average, the epigenetic age was 73 years in both groups, which represents a difference of over 20 years between epigenetic and chronological age in both affected and unaffected individuals. Methylation analysis revealed 11 DMRs between groups, which contain six genes and two pseudogenes. These genes are involved in cell cycle regulation, embryogenesis, synthesis of ceramides, and migration of interneurons to the cerebral cortex. One of the six genes is PM20D1, for which altered expression has been reported in LOAD. After genotyping previously reported mQTL SNPs for the gene, we found that average methylation in the PM20D1 DMR differs between genotypes for rs708727, but not for rs960603.ConclusionsThis work supports the possible role of PM20D1 in protection against AD, by showing differential methylation in blood of affected and unaffected nonagenarians. Our results also support the influence of genetic factors on PM20D1 methylation levels.
HOW TO JUSTIFY MANDATORY ELECTORAL QUOTAS: A POLITICAL EGALITARIAN APPROACH
Authors: Mráz Attila 
Published: December 2021

ABSTRACTThis paper offers a novel substantive justification for mandatory electoral quotas—e.g., gender or racial quotas—and a new methodological approach to their justification. Substantively, I argue for a political egalitarian account of electoral quotas. Methodologically, based on this account and a political egalitarian grounding of political participatory rights, I offer an alternative to the External Restriction Approach to the justification of electoral quotas. The External Restriction Approach sees electoral quotas as at best justified restrictions on political participatory rights. I argue for the Internal Restriction Approach instead, which can justify electoral quotas by specifying the pro tanto scope of political participatory rights rather than by justifying restrictions on the pro tanto scope of these rights. On this approach, adequately set electoral quotas do not even conflict with and are not balanced against political participatory rights, while electoral quotas—when justified—are pro tanto required rather than merely permitted.
Strengthening the primary health care response to COVID-19: an operational tool for policymakers
Authors: Johansen Anne S. , Shriwise Amanda , Lopez-Acuna Daniel , Vracko Pia 
Published: December 2021

Abstract

Aims:
The aim of this paper is to introduce an operational checklist to serve as a tool for policymakers in the WHO European Region to strengthen primary health care (PHC) services and address the COVID-19 pandemic more effectively and to present the results from piloting the tool in Armenia.

Backgrounds:
PHC has the potential to play a fundamental role in countries’ responses to COVID-19. However, this potential remains unrealized in many countries. To assist countries, the WHO Regional Office for Europe developed a guidance document – Strengthening the Health Systems Response to COVID-19: Adapting Primary Health Care Services to more Effectively Address COVID-19 – that identifies strategic actions countries can take to strengthen their PHC response to the pandemic. Based on this guidance document, an operational checklist was developed to serve as a tool for policymakers to operationalize the recommended actions.

Methods:
The operational checklist was developed by transforming key points in the guidance document into questions in order to identify potentially modifiable factors to strengthen PHC in response to COVID-19. The operational checklist was then piloted in Armenia in June 2020 as part of a WHO mission to provide technical advice on strengthening Armenia’s PHC response to COVID-19. Two WHO experts performed semi-structured, face-to-face interviews with nine key informants (both facility managers and clinical staff) in three PHC facilities (two in a rural and one in an urban area). The data collected were analyzed to identify underlying challenges limiting PHC providers’ ability to effectively and efficiently respond to COVID-19 and maintain essential health services.

Findings:
The paper finds that making adjustments only to health services delivery will be insufficient to address most of the challenges identified by PHC providers in the context of COVID-19 in Armenia. In particular, strategic responses to the pandemic were missed, due, in part, to the absence of COVID-19 management teams at the facility level. Furthermore, the absence of PHC experts in Armenia’s national pandemic response team meant that health system issues identified at the facility level could not easily be communicated to or addressed by policymakers. The checklist therefore helps policymakers identify critical challenges – at both the facility and health system level – that need to be addressed to strengthen the PHC response to the COVID-19 pandemic.
Carbon Ion Fluxes at Mars: First Results of Tailward Flows From MAVEN‐STATIC
Authors: Pickett N. B. , McFadden J. P. , Fowler C. M. , Hanley K. G. , Benna M. 
Published: December 2021

AbstractCharacterizing C+ ions in the Martian ionosphere is important for understanding the history of the Martian atmosphere and surface due to its place in understanding carbon escape. Measuring minor ions, like C+, which are close in mass to major atmospheric ions, in this case O+, is difficult, requiring fitting algorithms and accurate background subtraction. Accurate measurement of these species is essential for understanding chemistry and transport in the ionosphere. In this paper, we use data from the Mars Atmospheric and Volatile EvolutioN SupraThermal And Thermal Ion Composition (MAVEN‐STATIC) sensor to report the first C+ fluxes measured in the Martian magnetotail. We will describe a multistep method of background subtraction as well as fitting routines that are used to extract C+ fluxes from a 40‐orbit subset of STATIC data. Our results show tailward fluxes in both optical shadow and the adjacent sunlit magnetotail at high altitudes (3,000 km) and Mars‐ward at low altitudes (2,000 km) in shadow. These local flux values are similar to estimates of neutral carbon fluxes from photochemical escape. However, total carbon loss comparisons will require a more comprehensive study of integrated C+ loss over a larger data set from the Martian magnetotail.