bluuebunny/crossref_metadata_2025_split huggingface dataset:
INCIDÊNCIA DE ÓBITOS POR NEOPLASIAS, SEGUNDO LOCALIZAÇÃO PRIMÁRIA DO TUMOR NO ESTADO DO TOCANTINS DE 2006 A 2015.
Authors: Bitencourt Evandro Leite , Reis Júnior Paulo Martins , Rossato Renata , Araújo Sousa Bruno de Oliveira 
Published: May 2021

Objetivo: Fazer um levantamento de óbitos ocorridos por neoplasias segundo a localização primária do tumor no Estado do Tocantins de 2006 a 2015. Métodos: Os dados foram obtidos através de acesso ao sítio do Instituto Nacional do Câncer (INCA). A seleção dos dados foi feita de acordo com a Classificação Estatística Internacional de Doenças e Problemas Relacionados com a Saúde (CID-10) 10ª edição. O grande grupo do CID-10 selecionado foi o de Neoplasias [tumores] malignas (os) que engloba os CID de C-00 a C97. Resultados: As neoplasias que causaram maior mortalidade no Estado do Tocantins foram a neoplasia maligna de brônquios e pulmões seguida pela localização primária desconhecida, neoplasias malignas da próstata, mama, esôfago, estômago, pâncreas, fígado, colo do útero e leucemia mieloide. Quanto à faixa etária, a idade que registrou o maior número de óbitos foi de 70 a 79 anos. Conclusões: Com essa pesquisa, observa-se semelhança entre o perfil da mortalidade por neoplasias no Estado do Tocantins e o Brasil. Deve ser incentivada a criação de políticas públicas voltadas a essa patologia e conscientização da população na tentativa de evitar essa alta mortalidade.
Palavras-chave: Óbitos; Neoplasias; Sistemas de informação.
ABSTRACT
Objective: To make a survey of deaths due to neoplasms according to the primary location of the tumor in the state of Tocantins from 2006 to 2015. Methods: Data were obtained through access to the National Cancer Institute (INCA) website. Data were selected according to the International Statistical Classification of Diseases and Related Health Problems (ICD-10) 10th edition. The large group of ICD-10 selected was that of malignant neoplasms [tumors] that encompasses ICDs from C-00 to C97. Results: The neoplasms that caused the greatest mortality in the State of Tocantins were malignant neoplasms of the bronchi and lungs followed by the unknown primary site, malignant neoplasms of the prostate, breast, esophagus, stomach, pancreas, liver, cervix and myeloid leukemia. As for the age group, the age with the highest number of deaths was 70 to 79 years. Conclusions: With this research, there is a similarity between the profile of mortality due to neoplasms in the state of Tocantins and Brazil. It should be encouraged the creation of public policies aimed at this pathology and public awareness in an attempt to avoid such high mortality.
Keywords: Deaths; Neoplasms; Information systems.
SÍNDROME HELLP: A CONDUTA OBSTÉTRICA E SUAS CONTROVÉRSIAS
Authors: Oliveira Flávia da Silva , Moraes Fábio Roberto Ruiz de 
Published: May 2021

RESUMO
A síndrome HELLP pode ocorrer na pré-eclâmpsia (PE) ou na eclampsia e se caracteriza pelo conjunto de sinais e sintomas associados à hemólise microangiopática, elevação de enzimas hepáticas e plaquetopenia, podendo afetar 0,6% das gestações e 4-12% das pacientes com PE grave. Responsável por elevados índices de mortalidade materna e perinatal, a paciente pode apresentar-se com mal estar geral, epigastralgia, dor em hipocôndrio direito, náuseas ou vômitos, cefaléia, escotomas, associados a quadro hipertensivo e proteinúria. A conduta obstétrica na Síndrome HELLP ainda apresenta controvérsias na literatura, principalmente quando estamos diante de gestações em estágio inicial. Existem condutas favoráveis ao tratamento conservador no intuito de estabilizar a progressão da doença e reduzir a morbidade e mortalidade da mãe e do feto. Outras que postergam a interrupção da gestação por período de 48 horas nos menores de 34 semanas. E ainda temos condutas obstétricas que adotam a interrupção de emergência, independente da idade gestacional.
Palavras-chave: Síndrome HELLP, Pré-eclâmpsia grave, Eclâmpsia, gestação de alto risco.
ABSTRACT
HELLP syndrome is a clinical entity that can occur in pre-eclampsia or eclampsia and is characterized by presenting a set of signs and symptoms associated with mircroangiopathic hemolysis, raised elevated liver enzymes and thrombocytopenia, which may affect 0.6% of pregnancies and 4-12% of patients with severe PE. Responsible for high rates of maternal and perinatal mortality, the patient may present with general malaise, epigastralgia, right hypochondrium pain, nausea or vomiting, headache, scotomas, associated with hypertension and proteinuria. The obstetric behavior in HELLP syndrome is still controversial in the literature, especially when we are in the early stages of pregnancy. It was observed that some authors favor conservative treatment in order to stabilize the progression of the disease and reduce morbidity and mortality of the mother and the fetus. However, other authors take the course of postponing gestation of less than 34 weeks per 48-hour period. And we still have obstetric behaviors that adopt the emergency interruption, regardless of gestational.
Meta-Analysis of Smooth Muscle Lineage Transcriptomes in Atherosclerosis and Their Relationships to In Vitro Models
Authors: Conklin Austin C. , Nishi Hitoo , Schlamp Florencia , Ord Tiit , Ounap Kadri , Kaikkonen Minna U. , Fisher Edward A. , Romanoski Casey E. 
Published: May 2021

Abstract

Background:
Vascular smooth muscle cells (VSMC) exhibit phenotypic plasticity in atherosclerotic plaques, and among other approaches, has been modeled in vitro by cholesterol loading.

Methods:
Meta-analysis of scRNA-seq data from VSMC lineage traced cells across five experiments of murine atherosclerosis was performed. In vivo expression profiles were compared to three in vitro datasets of VSMCs loaded with cholesterol and three datasets of polarized macrophages.

Results:
We identified 24 cell clusters in the meta-analysis of single cells from mouse atherosclerotic lesions with notable heterogeneity across studies, especially for macrophage populations. Trajectory analysis of VSMC lineage positive cells revealed several possible paths of state transitions with one traversing from contractile VSMC to macrophages by way of a proliferative cell cluster. Transcriptome comparisons between in vivo and in vitro states underscored that data from three in vitro cholesterol-treated VSMC experiments did not mirror cell state transitions observed in vivo. However, all in vitro macrophage profiles analyzed (M1, M2, and oxLDL) were more similar to in vivo profiles of macrophages than in vitro VSMCs were to in vivo profiles of VSMCs. oxLDL loaded macrophages showed the most similarity to in vivo states. In contrast to the in vitro data, comparison between mouse and human in vivo data showed many similarities.

Conclusions:
Identification of the sources of variation across single cell datasets in atherosclerosis will be an important step towards understanding VSMC fate transitions in vivo. Also, we conclude that cholesterol-loading in vitro is insufficient to model the VSMC cell state transitions observed in vivo, which underscores the need to develop better cell models. Mouse models, however, appear to reproduce a number of the features of VSMCs in human plaques.
Energy Efficiency as a tool to improve buildings behavoir In Egypt. A frame work to achive low energy buildings locally.
Authors: Abd El Aal Heba Mahrous Ali 
Published: May 2021

Sustainable development goals for 2030 depending on how to create abetter life for pepole including all parameters which affect human to avoid the negative impacts of climate change which can destroy life on our plante.Saving energy is one of the main global problems, and buidings are one of the influences on energy consumption. It is a must to solve this problem by identifiy the causes which includinng the building features, operation process and the impact of its occupants . On the other hand, clarify permanent solutions according to modern concepts and techniques which can help to solve it locally.The study attempts to clarify human, nature environment and built environment impacts , in indicating how building Play an active role in achieving virous stages of energy consumption or production to adress the enegy effeciency importance.This paper discusses this issues and gives recommendations and proposals on how to solve problemsensure the achievement of low energy buildings in Egypt depending on the parameters which respect and depend on our local environment in Egypt.
The Association Between Using a Mobile Version of an Electronic Health Record and the Well-Being of Nurses: Cross-sectional Survey Study
Authors: Heponiemi Tarja , Kaihlanen Anu-Marja , Gluschkoff Kia , Saranto Kaija , Nissinen Sari , Laukka Elina , Vehko Tuulikki 
Published: May 2021

Background
Mobile devices such as tablets and smartphones are increasingly being used in health care in many developed countries. Nurses form the largest group in health care that uses electronic health records (EHRs) and their mobile versions. Mobile devices are suggested to promote nurses’ workflow, constant updating of patient information, and improve the communication within the health care team. However, little is known about their effect on nurses’ well-being.

Objective
This study aimed to examine the association between using a mobile version of the EHR and nurses’ perceived time pressure, stress related to information systems, and self-rated stress. Moreover, we examined whether mobile device use modifies the associations of EHR usability (ease of use and technical quality), experience in using EHRs, and number of systems in daily use with these well-being indicators.

Methods
This was a cross-sectional population-based survey study among 3610 Finnish registered nurses gathered in 2020. The aforesaid associations were examined using analyses of covariance and logistic regression adjusted for age, gender, and employment sector (hospital, primary care, social service, and other).

Results
Nurses who used the mobile version of their EHR had higher levels of time pressure (F1,3537=14.96, P<.001) and stress related to information systems (F1,3537=6.11, P=.01), compared with those who did not use mobile versions. Moreover, the interactions of mobile device use with experience in using EHRs (F1,3581=14.93, P<.001), ease of use (F1,3577=10.16, P=.001), and technical quality (F1,3577=6.45, P=.01) were significant for stress related to information systems. Inexperience in using EHRs, low levels of ease of use, and technical quality were associated with higher stress related to information systems and this association was more pronounced among those who used mobile devices. That is, the highest levels of stress related to information systems were perceived among those who used mobile devices as well as among inexperienced EHR users or those who perceived usability problems in their EHRs.

Conclusions
According to our results, it seems that at present mobile device use is not beneficial for the nurses’ well-being. In addition, mobile device use seems to intensify the negative effects of usability issues related to EHRs. In particular, inexperienced users of EHRs seem to be at a disadvantage when using mobile devices. Thus, we suggest that EHRs and their mobile versions should be improved such that they would be easier to use and would better support the nurses’ workflow (eg, improvements to problems related to small display, user interface, and data entry). Moreover, additional training on EHRs, their mobile versions, and workflow related to these should be provided to nurses.
Perbandingan Tingkat Motivasi Mahasiswa yang Menempuh Kuliah Konvensional dengan Collaborative Learning
Authors: Herman Herman , P Titi Savitri , Widyandana Widyandana 
Published: May 2021

Background: Collaborative learning is a learning method which centered on students’ learning process. Although many theories and research results showed that interactive lecture is better than conventional lecture, but in fact, only few lecturers use the interactive method in teaching and learning process. Literature stated that using conventional method in teaching and learning process does not motivate students to learn more while using the other one (interactive lecture) will enhance students’ motivation. Collaborative learning is one of interactive lecture method. Based on the facts mentioned above, the researcher wants to compare students’ motivation who participate in conventional method and those who participate in collaborative learning method.Method: This was a quantitative research with experimental approach, used posttest only with control group design. This research measured students’ learning motivation by using Motivated Strategies for Learning Questionnaire (MSLQ). Subjects for the research were the second semester students of Public Health Scince of Tadulako University which divided into two groups randomly. Data were analyzed by Mann-Whitney test method.Results: There were a distinct disparity in students’ learning motivation after following learning process with conventional and collaborative learning method. Students who followed collaborative learning had higher motivation than students who followed conventional lecture.Conclusion: Collaborative learning improves students’ learning motivation toward the nutrient topic on Public Health Sciences.
Perbandingan Sikap Menggunakan Komputer antara Dosen dan Anggota e-Learning Community
Authors: Adella Fidelis Jacklyn , Rukmini Elisabeth 
Published: May 2021

Background: E-learning community (eLC) of the School of Medicine Atma Jaya Catholic University of Indonesia consisted of twelve students. eLC trained lecturers about e-learning in personal or small group format. This study aimed to compare the differences between the development of computer-related attitude between lecturers and e-learning community members upon the service from e-learning community for lecturers. Method: This research was an experimental quantitative and qualitative study. Subjects were 12 students of eLC and 32 lecturers who received eLC’s services. The quantitative data was collected through questionnaires of the Computer Anxiety Rating Scale (CARS) and Computer Self-Efficacy (CSE). The qualitative data was collected through focus group discussion and in-depth interviews. CARS and CSE data were collected four times: (1) prior to the eLC trainings, (2) right after the eLC first training, (3) after the second training of eLC, and (4) right after one month of the last training from eLC. Data analysis was conducted using Friedman test, Mann-Whitney test. Qualitative data analysis were performed using content analysis.Results: There was a significant decrease from the score of CARS 1 to the score of CARS 4 for the eLC members (p=0,045). Results of CSE for eLC members showed no significant differences across the data collection. For faculty members, the significant differences were found between CARS 3 and CARS 4 (p=0,014). CSE scores of faculty members showed no significant differences. Comparison of CARS and CSE between faculty members and eLC members showed no significant differences. The qualitative data analysis showed some important aspects found in both of the groups. There are communication, interaction, the importances of eLC trainings, as well as suggestions to both of the groups about e-learning. Subjects’ opinions were divided into two groups: one who experienced positive changes in their computer-related attitude and one who did not experience any changes. Conclusion: Faculty members found that eLC were important in relation to e-learning training for lecturers. Students strongly agreed that being the member of eLC made him/her had a great opportunity to closely communicate to their lecturers. The faculty members’ anxiety level of computer using was low; on the other hand, their awareness of computer technology was good enough. The institution should employ this opportunity to apply e-learning more seriously and extensively.
Peningkatan Kompetensi Manajemen Asfiksia Bayi Baru Lahir Melalui Metode Cooperative-Learning
Authors: Kusuma Reni M. , Anwar Anita D. , Prasetyo Dwi 
Published: May 2021

Background: The competence of asphyxia management on newborn baby is essential for midwife. The quality of learning process should be improved by applying interactive learning method. The cooperative learning method is often applied to enhance the effectiveness of clinical learning process. The purpose of this research was to analyze the influence of cooperative learning on competence which consists of student’s knowledge, attitude, and skill in comparison to teacher-centered learning method.Method: This is quasi-experimental research with control group pre-test and post-test design Samples were third semester students at Stikes A. Yani Yogyakarta. The samples were 80 students in cooperative learning group and 90 students in teacher-centered learning group.Result: The result showed that there was an improvement of knowledge in cooperative learning group compared to teacher-centered learning group (p=0.002). The improvement od student’s attitude in cooperative learning group was significantly higher than teacher-centered learning group (p=0.001). In the field of skills, cooperative group, although not significant (p=0.671). The competence was significantly higher in cooperative learning group rather than in teacher-centered learning group (p=0.027). Correlation between competence and method of learning was weak (rpbi = 0.134, p= 0.041).Conclusion: Cooperative learning method is proven to be improve student’s knowledge, attitude and skills. The difference is not significant for skills domain. Cooperative learning method is proven to improve student’s competence in carrying out the management of newborn babies asphyxia, even though the correlation is weak.
Pembelajaran Profesionalisme Kedokteran dalam Persepsi Instruktur dan Mahasiswa
Authors: Purnamasari Cicih Bhakti , Claramita Mora , Prabandari Yayi Suryo 
Published: May 2021

Background: Profesionalism has become a main competency for physician. Therefore, it is important to get an agreement from health provider about professionalism and it’s applicable learning method for medical institution. This research aimed to explore skills laboratory instructor and student’s perception of the learning method that can facilitate the mastery of professionalism and it’s professional behavior components.Method: A descriptive qualitative method was carried out in this research. Data was collected by indepth interview among instructors and FGD among two groups of students, and analyzed by grounded theory method approach.Results: Medical professionalism is an integrated ability of knowledge, skill and attitude. Professional behavior formed by attitude. Professionalism can be learnt and taught by eksplisit, implisit and continuing education methods.Conclusion :. Medical professionalism can be collaborated in several learning methods. Role model is claimed as an effective learning method for medical professionalism and professional behavior mastery.
Efektifitas Pelatihan Kader Kesehatan dalam Penanganan Tuberkulosis di Wilayah Binaan
Authors: Boy Elman 
Published: May 2021

Background: Medan is an area with the largest TB patients in the North Sumatra Province. Since 2014, Medan Denai Distric is a target area of Medical Faculty of University Muhammadiyah North Sumatra (FM UMSU). One of the implemented program is formulating a Community Forum on TB Care. The objective of this study is to find out the effectiveness of TB management training by improving the knowledge of health cadres. Method: This was a one-group pre test-and post-test design. Participants of the research were all the TB care Forum members that was selected by inclusive criterias. Data collection was conducted by using quesionnaires of knowledge. Data analysis used Wilcoxon test with significancy level = 0,05.Results: The cadres knowledge significantly rise after the TB management training.Conclusion: TB management training for health cadre was effective in improving knowledge of health cadre.
Eksplorasi Sumber Imajinasi Mahasiswa tentang Profesi Dokter
Authors: Susani Yoga Pamungkas , Rahayu Gandes Retno , Sanusi Rossi , Prabandari Yayi Suryo , Harsono Harsono 
Published: May 2021

Background: In the process of becoming a doctor, a medical student experiencing the development of professional identity. In this process, students need a broad picture of medical profession. They need to orient themselves in the medical profession to determine the future professional identity as a doctor. Source of the picture of medical profession needs to be explored further. This study aims to explore the ways students get picture of the medical profession.Method: Qualitative research by conducting in-depth interviews to 17 preclinical and clinical medical students. Determinants and emergent coding performed to analyze the results of the interview.Results: Source of imagination can be derived from the curriculum and outside the curriculum. Students get two important things, first was overview of the work environment and how the physician work and second was physician professional values. Characters of role models identified primarily from student interaction with faculties. The characters include faculty’s role as teacher, as doctor, their personal atributes and how they interact with students.Conclusion: Formal curriculum plays important roles in providing and facilitating students to get overview about the work environment and how the doctors work in the health service. Although the transfer of professional value to students is determined by the hidden curriculum, but the formal curriculum can facilitate by providing activities that allows the interaction between generations or conduct review on fiction and non-fiction medical stories and histories that is obtained from media.
Self-Assessment dalam Kegiatan Diskusi Problem-Based Learning Fakultas Kedokteran: Kajian Naratif
Authors: Feri Rose , Simadibrata Marcellus , Jusuf Anwar 
Published: May 2021

Background: Student peformance assessment during problem-based learning (PBL) discussion is still debatable. One of the assessments that applies adult learning principle is self-assessment (SA). In fact, many medical schools prefer to use tutor assessment than SA because it is considered less accurate. Many studies have reported that the accuracy of SA is poor because of their own lack of knowledge and SA skills. This literature review aims to explore deeper in SA and its basic principles in designing SA instrument for PBL discussion in medical school.Method: This study was conducted using narrative review method. Ten articles were reviewed. Five articles were chosen from google search engine and the other five from medical education textbooks.Results: SA is the ability of a student to observe, analyze and assess his own performance based on the criteria and he determines a way to fix it. SA skills that have been practiced during PBL discussions will equip the students to become future health professionals who are competent in determining their own continuous professional development (CPD) programs. When designing a SA instrument, one needs to explore these five main issues, including acceptance, accuracy, power, feasibility and context.Conclusion: SA is the most effective assessment to assess a student’s achievement in PBL discussion if implemented properly. The completion of SA should be made in the normal context and one must explore the five main issues constantly so that SA can be done properly and well.