bluuebunny/crossref_metadata_2025_split huggingface dataset:
High-mass MALDI-MS unravels ligand-mediated G protein–coupling selectivity to GPCRs
Authors: Wu Na , Olechwier Agnieszka M. , Brunner Cyrill , Edwards Patricia C. , Tsai Ching-Ju , Tate Christopher G. , Schertler Gebhard F. X. , Schneider Gisbert , Deupi Xavier , Zenobi Renato , Ma Pikyee 
Published: July 2021

Significance
G protein–coupled receptors (GPCRs) are important pharmaceutical targets for the treatment of a broad spectrum of diseases. Upon ligand binding, GPCRs initiate intracellular signaling pathways by interacting with partner proteins. Assays that quantify the interplay between ligand binding and initiation of downstream signaling cascades are critical in the early stages of drug development. We have developed a high-throughput mass spectrometry method to unravel GPCR–protein complex interplay and demonstrated its use with three GPCRs to provide quantitative information about ligand-modulated coupling selectivity. This method provides insights into the molecular details of GPCR interactions and could serve as an approach for discovery of drugs that initiate specific cell-signaling pathways.
Agent control in passives in Romanian
Authors: Giurgea Ion , Cotfas Maria Aurelia 
Published: July 2021

Abstract
We examine control by the external argument of
passives in Romanian. As copular passives generally disallow clausal
subjects, this issue only concerns reflexive-based passives
(so-called ‘se-passives’). Although it is difficult
to find unequivocal control instances in Romanian due to the gradual
replacement of infinitives by subjunctives and the
nominative-licensing potential of infinitives, there are some verbs
for which control can be assumed (aspectuals and ability modals).
These verbs allow se-passives, but in this case
se must be repeated on the infinitive or
subjunctive complement. We argue that this does not represent voice
agreement under restructuring, but rather an instance of control,
involving matching between the external arguments
of the matrix and the embedded se-verbs, for which
we propose generation in an argument position, SpecVoiceP. Romanian
‘se-passives’ are analyzed as a construction
halfway between actives and passives, having a nominative theme
(with which T agrees) but also a projected external argument.
Control from inside
Authors: Matsuda Asako 
Published: July 2021

Abstract
Traditional assumptions hold that the reference
of complement control PRO is dependent on the reference of a higher
argument and that the lexical properties of the embedding predicate
are mostly responsible for controller determination. Against such
views, this study argues for the possibility that the reference of
certain instances of PRO (PC PRO) derives from its own internal
structure. The insight comes from Japanese data where certain force
suffixes appear in the complements of attitude predicates. These
forces are proposed to arise from C-PRO indexical
(speaker/addressee) agreement. Similar views have been presented in
my previous works (Matsuda
2015a; b,
2017a; b, 2019), with some revisions along the way.
This paper provides new supporting data and presents my revised
framework.
Adjunct control and the poverty of the stimulus
Authors: Gerard Juliana 
Published: July 2021

Abstract
Subject control in non-finite adjuncts is
observed across languages (as in ‘John called Mary after drawing a
picture’). Research on the acquisition of adjunct control has
generally focused on the relevant grammatical components and when
they are acquired. This paper considers these components in the
context of the linguistic input to ask how control in adjuncts is
acquired. Although adjunct control is available in the input, the
instances themselves do not provide evidence for abstract syntactic
relations. Implications are considered for linguistic dependencies
and the evidence in the input.
Gas cooling of test masses for future gravitational-wave observatories
Authors: Reinhardt Christoph , Franke Alexander , Schaffran Jörn , Schnabel Roman , Lindner Axel 
Published: July 2021

Abstract
Recent observations made with advanced LIGO and advanced Virgo have initiated the era of gravitational-wave astronomy. The number of events detected by these ‘2nd generation’ (2G) ground-based observatories is partially limited by noise arising from temperature-induced position fluctuations of the test mass (TM) mirror surfaces used for probing spacetime dynamics. The design of next-generation gravitational-wave observatories addresses this limitation by using cryogenically cooled test masses; current approaches for continuously removing heat (resulting from absorbed laser light) rely on heat extraction via black-body radiation or conduction through suspension fibres. As a complementing approach for extracting heat during observational runs, we investigate cooling via helium gas impinging on the TM in free molecular flow. We establish a relation between cooling power and corresponding displacement noise, based on analytical models, which we compare to numerical simulations. Applying this theoretical framework with regard to the conceptual design of the Einstein telescope (ET), we find a cooling power of 10 mW at 18 K for a gas pressure that exceeds the ET design strain noise goal by at most a factor of ∼3 in the signal frequency band from 3 to 11 Hz. A cooling power of 100 mW at 18 K corresponds to a gas pressure that exceeds the ET design strain noise goal by at most a factor of ∼11 in the band from 1 to 28 Hz.
Inflation from inhomogeneous polarized Gowdy model
Authors: Olmedo Javier 
Published: July 2021

Abstract
We study polarized Gowdy cosmologies on the three torus coupled to a massive scalar field. The phase space of the model admits a simple splitting between homogeneous and inhomogeneous sectors after a suitable gauge fixing. The presence of the mass term of the scalar field breaks the linearity of the equations of motion of the inhomogeneous fields. We discuss regimes of physical interest in which we recover a linear dynamics of these nonperturbative inhomogeneities, despite the metric is fully inhomogeneous at early times. We expand the inhomogeneous fields in Fourier modes and express them at all times as linear combinations of a basis of orthonormal complex solutions to the equations of motion, with coefficients that turn out to be an infinite collection of constants of motion. We argue that the resulting model can describe a nonperturbative inhomogeneous early Universe dominated by the kinetic energy of an inflaton at early times that can eventually reach a slow-roll regime with a nearly exponential expansion at late times that isotropices and homogenizes the geometry.
A study of scalar optically-pumped magnetometers for use in magnetoencephalography without shielding
Authors: Clancy Richard J , Gerginov Vladislav , Alem Orang , Becker Stephen , Knappe Svenja 
Published: July 2021

Abstract
Scalar optically-pumped magnetometers (OPMs) are being developed in small packages with high sensitivities. The high common-mode rejection ratio of these sensors allows for detection of very small signals in the presence of large background fields making them ideally suited for brain imaging applications in unshielded environments. Despite a flurry of activity around the topic, questions remain concerning how well a dipolar source can be localized under such conditions, especially when using few sensors. In this paper, we investigate the source localization capabilities using an array of scalar OPMs in the presence of a large background field while varying dipole strength, sensor count, and forward model accuracy. We also consider localization performance as the orientation angle of the background field changes. Our results are validated experimentally through accurate localization using a phantom virtual array mimicking a current dipole in a conducting sphere in a large background field. Our results are intended to give researchers a general sense of the capabilities and limitations of scalar OPMs for magnetoencephalography systems.
Nutrient concentration of nitrogen and phosphorus on intercropping of several varieties maize and soybean in dryland North Lombok, Indonesia
Authors: Astiko W , Ernawati N M L , Silawibawa I P 
Published: July 2021

Abstract
The reduction in agricultural land due to land conversion and climate change has encouraged several technological innovations in cultivation systems, including intercropping planting patterns in dryland. Dryland is a potential future as productive agricultural land and to improve the efficiency of land use and the intercropping system is an option in agricultural cultivation. The objective of this research was to determine the nutrient concentration of nitrogen and phosphorus on intercropping several varieties of maize and soybean in dryland. The method used in this study was a randomized block design with 5 treatment intercropping varieties combination of maize and soybean, namely V1 = NK212: Biosoy I, V2 = Bima 20 URI: Dega I, V3 = NASA 29: Detap, V4 = Bisi 18: Biosoy II, V5 = Srikandi Kuning: Anjasmoro. Each treatment was repeated three times to obtain 15 experimental plots. Parameters that were observed in this study, namely, the concentration of N, P, organic C content and pH of the soil at 40 das (day after seedling) and 92 das, uptake of N and P per plant at 40 das. Data were analyzed using analysis of variance at 5% significance level and if the treatment was significantly different then further tested using LSD at 5% significance level. The impact of climate change is the occurrence of a shift in the nutrient concentration of N, P, C-organic content, and pH in the soil at 40 or 92 das and the uptake of N and P nutrients in the plants at 40 das on intercropping maize varieties Bisi 18 and soybean varieties Biosoy II obtain the highest value. This study recommends that the improvement of nitrogen and phosphorus status in climate change can be achieved by intercropping Bisi 18 corn and Biosoy II soybeans in the dryland of North Lombok.
The effect of micro fertilizer on growth and yield of two cassava clones (Manihot esculenta Crantz) planting in early dry-season, South Lampung, Indonesia
Authors: Setiawan K , Paringin A E D , Yuliadi E , Hadi M S , Ardian  
Published: July 2021

Abstract
Drought is one of the important climate changes that could affect the early planting of cassava to produce a high yield. Lampung province having a specific climate, wet tropical dry-season is the center of cassava production in Indonesia. Consequently, the objective was to evaluate the effect of micro fertilizers on the growth and yield of two cassava clones planting in the early dry season. This research was conducted on Ultisol soil of Tanjung Bintang District, South Lampung from May 2019 to April 2020. Treatment was arranged by factorial (2x2) in a Randomized Complete Block Design (RCBD) which 3 replications. The first factor was two applications of micro fertilizer, 0 and 40 kg ha−1. The second factor was two cassava clones, UJ-5 and BW-1. Results showed that the leaf number of UJ-5 at 6 MAP and 9 MAP was increased by micro fertilizer. Yet, the leaf number of BW-1 at 6 MAP and 9 MAP was not increased by micro fertilizer. It seems that UJ-5 could be more tolerant to drought in early planting time. Consequently, the tuber fresh weight of UJ-5 was heavier due to micro fertilizer but lower starch content compared to BW-1. It could be concluded that UJ-5 when planted at early dry-season would show higher tuber fresh weight with lower starch content than BW-1.
Estimation of peak runoff impact from land use change using remote sensing and GIS in Keduang sub-watershed
Authors: Muttaqin Alfan , Suntoro  , Komariah  
Published: July 2021

Abstract
Changes in land use in watersheds and climate change have a dominant influence on watershed hydrology. One of the important aspects of watershed hydrology related to land use change and climate change is runoff. Land use changes in the watershed area from non-built areas to built areas or vegetated areas to non-vegetated areas will increase runoff. Because vegetation helps absorb rainwater optimally into the soil. Thus, rainwater that falls to the ground will become more runoff. For this reason, it is necessary to conduct a study to determine the land use changes and impact on the runoff, as has been done in the Keduang sub-watershed, Wonogiri District, Indonesia. Land use change and peak runoff were estimated using remote sensing and Geographic Information System (GIS). Remotely sensed images from the Landsat satellites were used to develop land use maps of the study area in 2009 and 2020. The peak runoff was computed by the Rational Method. The land use map between 2009 and 2020 shows an increase in built areas and dryland agriculture and a decrease in the vegetated area such as a forest and mix garden. The impact of land use change increases the coefficient runoff value in the study area from 0.22 to 0.24. The results showed that peak runoff for 2009 was 358.73 m3/s and in 2020 was 363.38 m3/s there is an increase of 4.66 m3/s.
Analysis of vegetation in recharge area as climate change mitigation for conserving water springs in Keduang Sub-Watershed
Authors: Yuliantoro D , Budiastuti M T S , Mujiyo  
Published: July 2021

Abstract
Keduang Sub-Watershed is one of the priority watershed experiencing drought. Drought occurs due to the lack of water resources. The water resources are mostly affected by the climate change phenomenon, causing precipitation by the raising of temperature. The effort of water springs conservation is needed to maintain the existence of water springs. Agroforestry on recharge area was a mitigation effort of the water springs conservation. Mitigation activity for conserving water springs is begun by vegetation analysis in recharge area, relating to the frequency, density, dominance, and the important value index (IVI) of the species. The existence of vegetation in the recharge area has functioned as a protector and regulator of the water system. The study aims to identify the type of vegetation in the recharge area in the Keduang sub-watershed. It was conducted by taking data of all vegetation. The method of the study was a swath line, with a swath measurement of 20m x 20m used to collect data of tree, 10m x 10m to collect data of pole, and 5m x 5m to collect data of seedling. The data were analyzed by analysis of vegetation to get the frequency, density, dominance, and the IVI of species. The result showed that the type of vegetation in the recharge area in the Keduang sub-watershed has an important score of more than 10% consisting of 5 classes. The important score showed that Jati (Tectona grandis) as a tree was the highest followed by Sengon (Albizia falcataria) as a pole, and Johar (Cassia Siamea) as a seedling.
The relationship between water quality and prevalence of ectoparasites on cultured Nile tilapia at two reservoirs in Central Java, Indonesia
Authors: Kolia W S K , Sunarto  , Widiyani T 
Published: July 2021

Abstract
Besides environmental impacts, climate change is likely to cause a profound disruption to aquatic organisms. Therefore, parasitic infections could become more detrimental to host fish due to climate change in the future. This study aims to assess the relationship between the prevalence of ectoparasites Gyrodactylus spp., Dactylogyrus spp., and Trichodina spp. on cultured Nile tilapia and the water quality parameters of the Gajah Mungkur and Cengklik reservoirs. The standard parasitological procedure was used to determine the prevalence of these ectoparasites species. The water quality parameters conductivity, pH, dissolved oxygen, transparency, ammonia level, and temperature were measured. The results showed a high prevalence of 73% recorded by protozoan Trichodina spp followed by 30.1% and 25.3 % for Dactylogyrus spp., and Gyrodactylus spp., respectively. Furthermore, the findings showed that the prevalence of ectoparasites correlated with water quality in different ways in each reservoir. The presence of ectoparasites in the Gajah Mungkur reservoir was primarily influenced by ammonia level and temperature. Besides, in the Cengklik reservoir, ectoparasites were the most influenced by water pH. There was no fish mortality recorded despite the parasitic infection. The water quality parameters were within the recommended range for tilapia culture under cage systems.
The Study of nutrient removal and implementation of organic farming on broccoli cultivation to anticipate climate change
Authors: Irsan F , Riyanto D 
Published: July 2021

AbstractThe excessive use of chemical fertilizers and pesticides continuously has some problems faced by farmers in horticulture cultivation. Implementation of an organic farming system is one way to adaptate climate change for sustainable agriculture, improves soil quality, reducing of the detrimental effect on water quality, and efficient in the use of non-renewable energy. This study aim to determine the level of N, P and K removal, the growth and yield of broccoli on the three kinds of cropping systems in Batur, Getasan-Semarang. The research used a Completely Randomized Block Design with 3 treatments, namely organic, semi-organic, and conventional farming, and replicated 6 times. The soil and plant sampling were used the survey method and broccoli were harvested 8 and 10 weeks after planting. Soil properties analysis was taken before the experiment ongoing, including pH, N-total, C-organic, P-total and P-available, K-total and K-available, CEC, Particle density, Bulk density, and Percentage of total porosity. Plant growth parameters were carried out on 6, 8, and 10 weeks The result of study showed that the chemical and physical properties of the soil in the organic broccoli cultivation better than semi-organic and conventional farming, which proved by soil pH, organic C, total N, P, and K available have a higher value, while the particle density and soil bulk density have a lower value. Moreover, the total porosity and permeability have a higher value compared to conventional farming. Growth and yield of fresh broccoli by the organic farming system are increased about 21.81% and 31.43%, respectively than the conventional farming.
Land use changes impact on water quality in Jeneberang Watershed, South Sulawesi, Indonesia
Authors: Suwardi  , Budiastuti M T S , Komariah  
Published: July 2021

Abstract
Land use change and water quality problems occur in most watersheds in Indonesia, which are also resulted by climate change phenomenon. One of the watersheds that have a critical status but have an important role in South Sulawesi, Indonesia is the Jeneberang watershed, which is included in 15 national priority watersheds for restoration and conservation. The purpose of this study is to analyze the impact of land use changes in watersheds over the last 20 years on water quality. This research is a descriptive study using quantitative and qualitative methods. In this study, Land Change Modeler (LCM) module was used in Idrisi Terrset software to analyze changes in used/covered by comparing the imagery of 2000 and 2020, while water quality analysis using the pollution index method on 7 key parameters of water quality. The results showed a decrease in forest area cover in the upstream part of the watershed with an increase in the area of agricultural areas and settlements. Water quality was classified as lightly polluted with the pollution index values increased from upstream (2.04), middle (2.12,) to downstream (2.83). Biological Oxygen Demand (BOD), Chemical Oxygen Demand (COD), and Coliform concentrations were higher than national standards of water quality. Changing land use into agricultural areas and settlements has contributed to increased water pollution in the Jeneberang watershed.
Biofilm biofertilizer increase mustard growth and nutrient status of dry land Lithosols
Authors: Sudadi  , Suryono  , Triharyanto Edy 
Published: July 2021

Abstract
Almost all sectors including agriculture have the risk of being affected by global climate change. It need strategies and prepare adaptation action programs with the support of innovative and adaptive technologies to anticipate. This research aimed to find out an appropriate dosage of organic fertilizer decomposted by biofilmed biofertilizer (OF-Bio2) that optimally increases mustard growth as well as N, P and K status at Lithosols. The experiment was done in a single factor randomized completely block design (RCBD) with eight dose levels, i.e. 0, 3, 6, 9, 12, 15, 18, and 21 ton ha−1 of OF-Bio2 on 2 x 3 m2 plot and 15 x 20 cm planting spaces. OF-Bio2 was incorporated thoroughly within 20 cm depth of the soil and one mustard plantlet was planted in each planting hole. Plant height, fresh and dry weights were observed and soil organic carbon (SOC), total-N, av-P and exch-K content were analysed at harvest time. Data were analysed by F-test followed by Duncan multiple range test (DMRT) at 95% of confidence level. The result showed the use of OF-Bio2 increased mustard growth linearly as well as N, P and K status concomitantly with the increase of OF-Bio2 doses. An optimal dose of OF-Bio2 for mustard yield was not achieved yet, because of low organic matter content of the soil. The use of biofilm biofertilizer to decompose organic fertilizer will support sustainable soil nutrient management with more effective soil microbes enable to increase nutrient available.
The density and diversity of Arbuscular mycorrhizal spores on land covers with different tree canopy densities at the UNS educational forests
Authors: Dewi W S , Prasidina S D C , Amalina D D , Wongsoatmojo S 
Published: July 2021

Abstract
Mycorrhiza is a ‘super-organism,’ potential to support plants facing increment temperatures due to more open tree canopy cover. This research aimed to study how three different land covers affect the abundance and diversity of mycorrhiza spores in the UNS educational forests. The research was descriptive-explorative with a survey approach on three land covers with different canopy densities, i.e.: (1) mahogany, (2) pine, and (3) pine replanting, with a canopy cover of 95.56%, 80.93%, and 16.50%, respectively. Soil samples were taken by purposive random sampling at several points at a soil depth of 0-30 cm in a 200 m2 transect, then composited. Repeated each land cover was four times. The results showed that land cover with a more open canopy had a higher density of mycorrhiza spores than a dense canopy. The spores’ density on the land cover of Pine replanting> Pine> Mahogany was 865, 761, and 608 spores/100 g of soil, with a diversity index (H’) 1.00; 0.63; and 0.88, respectively. The types of spores found were Gigaspora sp., Glomus sp., and Archaeospora sp. Mycorrhizal spore density was related to soil temperature (r = 0.56*) and C-organic (r = - 0.68**). Mycorrhizae provide new hope to support plant tolerance facing higher temperatures due to climate changes at the UNS educational forests.