bluuebunny/crossref_metadata_2025_split huggingface dataset:
O impacto do tratamento odontológico na percepção de qualidade de vida em adolescente
Authors: Lima Vivine Silva , Marques Daniella Bitone Pinheiro , Souza Ana Clara Pereira de , Francisco Everton Mateus Pina , Azevedo Karen Bianca Pereira , Souza Michele Silva , Almeida Paloma Barbosa , Rocha Thainara Lima Canguçu da , Melo Maria José Lopes de 
Published: February 2025

Objetivo: Relatar um caso de um paciente para avaliar o impacto das condições bucais, antes e pós tratamento odontológico, na qualidade de vida de adolescente escolar, medida através do questionário OHIP14. Detalhamento de caso: Paciente masculino, 16 anos, apresentou destruição coronária por cárie dos incisivos centrais e laterais superiores. Relatava dor, dificuldade em alimentar-se e, por vergonha de falar e sorrir, restringiu o convívio social, incluindo o ambiente escolar. Os testes clínicos, percussão, vitalidade pulpar e as radiografias periapicais indicaram comprometimento pulpar com o diagnóstico de pulpite irreversível. Na abordagem inicial realizou-se a aplicação do questionário Oral Health Impact Profile (OHIP14), posteriormente, foi realizado o tratamento odontológico. No período de um ano, o questionário foi reaplicado. Os resultado foram obtidos comparando os questionários, foi observado no primeiro questionário, um impacto negativo significativo no bem estar do participante devido à problemática com seus dentes e observou-se uma mudança significativa nas respostas no período de um ano, Considerações finais: A odontologia desempenha um papel de relevância nas relações psicossociais dos indivíduos, restabelecendo a autoestima, devolvendo forma, função e estética ao sorriso. O tratamento odontológico apresentou-se como ferramenta de ressocialização e bem estar psicológico do adolescente desse estudo.
Avaliação da Acurácia Posicional de Sensor LiDAR Incorporado em Smartphones
Authors: Moreira Gonçalves Enrico , Luiz Albarici Fabio 
Published: February 2025

Recentemente, foram introduzidos, pela Apple Inc. dispositivos móveis com sensor LiDAR incorporado. Esses dispositivos podem oferecer uma alternativa econômica e versátil, superando algumas das limitações dos sistemas tradicionais baseados em LiDAR. Nesse contexto, este trabalho avaliou a precisão de nuvens de pontos gerados por smartphones com a tecnologia LiDAR incorporada. A metodologia empregada envolveu a análise das coordenadas tridimensionais de pontos de interesse na nuvem de pontos com coordenadas tridimensionais dos mesmos pontos levantadas por meio de uma estação total. Os testes numéricos demonstraram consistência nas coordenadas, com discrepâncias absolutas abaixo de 8,5 cm e uma distribuição normal das discrepâncias em torno da média. A acurácia média dos pontos foi de 2 cm, com a maioria dos pontos apresentando precisão entre 1,6 cm e 2,5 cm. Esses resultados indicam que os dispositivos móveis equipados com LiDAR são capazes de produzir modelos digitais de terreno com precisão suficiente para aplicações na maioria dos trabalhos em engenharia e geociências, fornecendo uma alternativa acessível e conveniente em relação aos levantamentos com laser scanner topográfico.
Dendrimer multifunctional complexes for genetic therapy of cancer
Authors: Stanovaya A. , Terekhova M. , Abashkin V. , Ulashchik E. , Shcherbin D. 
Published: February 2025

Every year there is a rapid increase in cancer, which is one of the main causes of death. Methods used to treat cancer often do not produce the desired results and can cause various side effects. Therefore, to effectively combat cancer, it is necessary to find new solutions. The use of nanotechnology opens up new opportunities in the diagnosis and treatment of human malignant tumors. Nanoparticles used in antitumor therapy can act as carriers of drugs and nucleic acids, and also reduce the toxicity of anticancer drugs. This review is devoted to the analysis of the interaction of various nanomaterials with small anticancer RNAs. Data are presented on the use of some non-toxic and effective multifunctional nanoconjugates in gene therapy for the treatment and diagnosis of cancer.
Synergistic Antiproliferative Effect of Linagliptin-Metformin Combination on the Growth of Hela Cancer Cell Line
Authors: Ahmed Abdulkareem , Nihad Ahmed , Sabreen Ghaeeb , Youssef Yasin , Azal Jumaa 
Published: February 2025

This in-vitro study explores the cytotoxic properties of the linagliptin-metformin combination on cervical cancer cells and examines the synergistic interaction between the two drugs. An MTT assay was used to explore the anti-cancer effects of the linagliptin-metformin mixture on a cervical cancer cell line (HeLa cell line) across 24 and 72-hour incubation periods. The concentrations of metformin, linagliptin, and their combination ranged from 0.1 to 1000 µg/ml. while the concentrations in the mixture were kept at fifty percentage of the individually used drug. The study included an estimated combination index value (CI) and the dosage reduction index (DRI) to ascertain the possibility of a synergistic effect between combined drugs and mixture safety. study finding exhibited that all studied drugs- metformin, linagliptin, and their combined mixture- inhibited the growth of cervical cancer cells with a superior efficacy of the mixture over individual drugs. Inhibition patterns of the drugs were directly proportional to the drug's concentration and the incubation time. The combination index finding revealed that the mixture's cytotoxic effect of metformin and linagliptin was synergistic. The dose reduction index value revealed that lower drug concentrations were required in the combination mixture than when used individually indicating a greater cytotoxic potential of the mixture. The study findings of MTT, CI, and DRI indicate that the mixture is an effective, safer, and promising anticancer therapy for cervical cancer.
Conclusion: This study explores the cytotoxic potential of metformin and linagliptin individually and in combination. The greater cytotoxic potential of the drugs in combination highlights their lower effective concentrations, paving the way for further research on using these drugs for effective cancer treatment.
Exploring potential of zero waste fashion design in fashion industry: A case study in men’s shirt
Authors: Fadhilaturrahmah Fadhilaturrahmah , Nursari Faradillah , Larissa Tiara , Putri Shella Wardhani 
Published: February 2025

<p>The background of this research investigates the application of Zero Waste Fashion Design (ZWFD) in the men's shirt industry, aiming to minimize textile waste and enhance sustainability. Using a qualitative methodology, the study conducts in-depth interviews with fashion designers and directly observes the design and production processes, focusing on the case study of Men's Shirts. Three emerging designers experiment with ZWFD techniques, resulting in successful explorations that produce textile waste well below 15%. Despite methodological variations, all efforts meet ZWFD criteria, demonstrating the efficacy of ZWFD in waste reduction and the creation of unique garment designs. The results of this study underscore the potential of ZWFD in men's shirt production and advocate for its broader adoption in the fashion sector to promote environmental and social sustainability. The conclusion is that to maximize the impact of ZWFD, further understanding of techniques and strategies for mass production implementation is crucial for reducing textile waste and advancing sustainable product development. Recommendations for future research and implications for industry practice are discussed, emphasizing the importance of sustainable fashion initiatives in addressing environmental challenges. </p>
Deteksi Cyberbullying Tweet Menggunakan Machine Learning
Authors: Safitri Maulina , Zafira Najwa Alhaura , Putri Adinda Dyahrestu , Pamungkas Sabrina Putri , Azahrah Fatimah , Lestari Ajeng , Kusdiyah Diajeng , Parwati Ni Wayan 
Published: February 2025

Menurut The United Nations Children’s Fund (UNICEF) cyberbullying merupakan penindasan ataupun perundungan dengan memakai teknologi digital. Perihal ini bisa terjalin di media sosial, platform pengiriman pesan, platform permainan, ataupun telepon seluler. Aksi ini dicoba secara kesekian yang diperuntukan buat menakut- nakuti, membuat marah, ataupun mempermalukan orang- orang yang jadi sasaran. Cyberbullying merupakan aksi yang sangat merugikan serta dapat mempunyai akibat emosional serta psikologis yang sungguh- sungguh pada korban. Penting untuk mengambil tindakan untuk melindungi diri sendiri dan melaporkan tindakan tersebut kepada pihak berwenang atau penyedia platform media sosial. Perihal ini butuh dicoba oleh korban ataupun siapa juga yang melihat aksi tersebut. Penelitian ini mengklasifikasikan data kedalam kelas cyberbullying dan not cyberbullying menggunakan metode machine learning, yaitu BiLSTM (Bidirectional Long Short-Term Memory), BERT (Bidirectional Encoder Representations from Transformers), dan RF (Random Forest), untuk mengetahui cyberbullying atau bukan. Ditemukan bahwa BERT mencapai akurasi sebesar 94%, serta f1 score 89% sehingga lebih unggul dalam menanggulangi ketidakseimbangan data. Hasilnya menampilkan kalau akumulasi penambahan kata kunci memakai TF-IDF dan borda rangking hasil ekstraksi kata dapat meningkatkan akurasi sampai 80%. Sentimen analisis memakai Majority Voting, K-Means Clustering, dan BERT menunjukkan hasil akurasi 83%, dengan label sentimen positif, negatif, sangat positif, dan sangat negatif.
Adult Children Migration and Perceived Mental Health of Elderly Parents in Rural Area of Parbat
Authors: Sharma Anju Kumari , Tamrakar Neeta , Karmacharya Ranjita 
Published: February 2025

Introduction: Increasing trend of elderly population across the world along with the increased rate of adult children migration has brought in significant impact on mental health of elderly population which has been a major concern nowadays. This study aimed to assess relationship of adult children migration and perceived mental health of elderly parents in the rural area of Parbat.
Methods: A descriptive cross- sectional study was conducted among 190 elderly parents of Modi rural municipality of Parbat district. A structured interview with validated Nepali version of DASS-21 (Depression, Anxiety, and Stress Scale) was used to assess the perceived mental health of elderly parents.
Results: Study findings showed that 57.9% respondents had at least one migrant child. Depression, anxiety and stress were prevalent among 15.8%, 28.9% and 13.2% respondents respectively. Perceived mental health of the respondents was significantly associated with age, gender, educational status, marital status, living arrangement and use of internet services (p<0.05). Stress among respondents was associated (p=0.016) with migration of adult children.
Conclusions: Mental health problems are prevalent among elderly parents and children migration is the significant influencing factor for mental health among them.
Prevalence and Pattern of Peptic Ulcer Disease among Patients Undergoing Upper Gastrointestinal Endoscopy in Koshi Hospital: A Cross-Sectional Descriptive Study
Authors: Thakur Manoj Kumar , Yadav Rohit Kumar , Yadav Rajeshwar , Sharma Priyanka 
Published: February 2025

Background: Acid peptic disease is one of the most common diseases encountered in outpatient department. There has been limited study on prevalence of different types of peptic diseases among patients undergoing upper gastrointestinal endoscopy especially in eastern part of Nepal. The aim of this study was to find out prevalence of different types of peptic diseases and study the socio-demographic profile of patients attending our medicine department.
Materials and Methods: A cross-sectional descriptive study conducted from April 2024toSeptemer 2024 who presented with symptoms of dyspepsia and features of upper gastrointestinal bleeding in medicine department were included. Data were collected from patient charts, endoscopy reports and pathology report. Statistical analysis was done using statistical package for the social sciences (SPSS) software version 17.
Results: A total of 569 patients were evaluated, among them 281 were males (49.4%) and 288 (50.6%) were females. Gastritis both nonerosive 219 (38.5%) and erosive 136 (23.9%) were common endoscopic findings. It was followed by gastric ulcer 65 (11.4%) and duodenal ulcer 27(4.7%). Normal endoscopic finding was present in 63 (11.07%). The prevalence of different types of peptic diseases was 88.9 percent among patients undergoing endoscopy. The peak incidence of peptic ulcer disease was present in age groups 40-60. Gastric ulcer and duodenal ulcer were significantly higher in male whereas non erosive gastritis was significantly higher in female.
Conclusion: Acid peptic disease is very common in patients undergoing endoscopy in our center. Gastric ulcer and duodenal ulcer were significantly higher in males whereas non erosive gastritis was significantly higher in females. Racial variation in peptic ulcer disease was not statistically significant.
Ergonomic practices and banking employee performance
Authors: Karmacharya Sadin , Bhattarai Ujjwal , Timsina Baburam , Shrestha Nishesh , Tamang Sanjita 
Published: February 2025

Using the sequential explanatory method, this study sheds light on the influence of ergonomics practices on the performance of banking employees. Data from 267 banking employees were collected and analyzed Via PLS-SEM, and using Heidegger’s interpretative philosophy, a semi-structured interview was conducted purposively with seven frontline employees. The study found that cognitive and organizational ergonomics significantly predict employee performance, while environmental and physical ergonomics were not supported. Thematic analysis identified four major themes: physical ergonomics and comfort, environmental ergonomics and workspace design, cognitive ergonomics and mental workload, and organizational ergonomics and support systems. This study highlights the importance of cognitive and organizational ergonomics, challenging traditional ergonomic models and offering practical recommendations for optimizing work environments in customer-focused and knowledge-intensive industries.
Application of Artificial Neural Network Algorithm with Principal Component Analysis for Diagnosis of Breast Cancer Tumors
Authors: Almunawar Muhammad Irfan , Maulana Reffy , Sumbogo Rifqi Putrawan 
Published: February 2025

Cancer is a health disorder where abnormal cells proliferate uncontrollably and is the second leading cause of death worldwide. Breast cancer, in particular, is prevalent among women in Indonesia. This study aims to diagnose breast cancer, identifying whether it is malignant or benign, using Artificial Neural Network (ANN) algorithms to enhance the accuracy of tumor diagnosis. The fundamental principle is to develop a neural network capable of processing information efficiently without relying on Python packages such as scikit-learn. The ANN operates through forward propagation and backward propagation to optimally predict outcomes and update weights. The dataset used is from the UCI Machine Learning Repository, consisting of 569 samples and 30 features. This dataset is divided into a training set (80%) and a cross-validation set (20%). The ANN model comprises one input layer, two hidden layers, and one output layer, utilizing tanh activation functions for the hidden layers and a sigmoid activation function for the output layer. Training results indicated an accuracy of 95.6% on the training set and 93.2% on the cross-validation set. This demonstrates that the model performs well in detecting breast cancer, with a low error rate and strong generalization capability. This study successfully developed an effective and reliable ANN model for breast cancer detection with high accuracy, supporting clinical breast cancer diagnosis.
Implementation of MVC Architecture in a Web-based Mail Management System (E-Archive)
Authors: Setiadi Ade , Alfiah Fifit , Ardiansah Teddy , Bin Ladjamudin Al Bahra , Haryanto Haryanto 
Published: February 2025

Companies, business entities, and institutions—both private and government—need archival activities because they are very important. To do it well requires improvement and refinement to achieve goals. All organizations, both government and private, must have complete and accurate data and information, knowing how important archiving is to assist leaders in making decisions or dealing with problems at the Larangan District Office, Tangerang City. Especially in the general section, archiving and document activity processes are still conventional, so it take a long time to complete. Because data is spread across many places and uses many formats, the process of selecting and reporting data is difficult to process well. This web-based electronic archiving system will be created using the Laravel framework and implementing the MVC(Model-View-Controller) architecture as a powerful and widely used software design pattern that encourages separation of concerns, code reuse, and maintainability enabling the archiving of incoming mail and mail. out serves as a data storage location. Therefore, the new e-archive system is expected to reduce errors when processing data, make the search process faster, and make reports that are in accordance with existing data.
Leukocyte Glucose Index as Significant Marker of Poor Prognosis in COVID-19 Patients with Hyperglycemia
Authors: Al-Nimer Marwan , Merza Talar A. , Jawad Thaqeef M. , Latif Ismail I. 
Published: February 2025

Background: Both diabetes mellitus (DM) and stress hyperglycemia (SH) are common findings in complicated or critically ill COVID-19 patients.
Objective: This retrospective study aims to assess leukocyte glucose index (LGI) as a prognostic marker for the outcome of COVID-19 patients.
Methodology: This retrospective study was conducted at the College of Medicine, University of Diyala, Iraq. Patients with COVID-19 were randomly allocated. A primary outcome of this study was clinical outcomes in terms of surviving or not surviving.
Results: 187 patients in total were included in the study and divided into three groups. Group I (n = 45) survived patients, Group II (n = 90) survived patients with complications, and Group III (n = 52) non-survived patients. The baseline data showed significant differences between Groups III, I, and II. The median values of LGI were significantly (p <0.001) higher in Group III (2.911) compared with Group I (1.754) and Group II (1.728). The odds ratio of DM, SH, and LGI (a cutoff value of 1.5) as a risk of mortality is 2.361, 7.333, and 4.842, respectively.
Conclusion: Leukocyte glucose index is a worse marker for COVID-19 patients with overt diabetes or stress hyperglycemia.
Bangladesh Journal of Infectious Diseases, December 2024;11(2):102-107
How does physical education influence university students’ psychological health? An analysis from the dual perspectives of social support and exercise behavior
Authors: Han Xu , Li Haozhen , Niu Ling 
Published: February 2025

ObjectivePhysical education, as a central component of educational systems, plays a unique role in enhancing the psychological well-being of university students. This study investigates the impacts of physical education on students’ mental health and examines the mediating roles of social support and exercise behavior.MethodologyA cross-sectional survey was conducted using the Physical Education Satisfaction Scale, SCL-90, the Social Support Questionnaire, and the International Physical Activity Questionnaire. A total of 1,437 university students were assessed.ResultsThe research found a positive correlation between physical education at universities and students’ mental health, with a direct significant effect (β = 0.622, p &lt; 0.001). Moreover, physical education positively influenced social support and exercise behavior (β = 0.523, p &lt; 0.001; β = 0.473, p &lt; 0.001). In turn, social support significantly fostered exercise behavior and improved mental health (β = 0.578, p &lt; 0.001; β = 0.277, p &lt; 0.001). Additionally, enhanced exercise behavior positively contributed to better mental health (β = 0.357, p &lt; 0.001).ConclusionPhysical education is a crucial influencing factor for university students’ psychological health and also indirectly impacts mental well-being through improved social support and increased exercise behavior.
Multi-level determinants of vaccination of the American Indian and Alaska Native population: a comprehensive overview
Authors: Zhao Junying , Jaggad Rashmi , Zhang Ying , Campbell Janis E. , Ghosh Pallab K. , Kennedye James R. , Ali Tauqeer 
Published: February 2025

ContextAmerican Indians and Alaska Natives (AIANs) are historically disadvantaged, losing 20 million (95%) of their population largely through epidemics since 1,520 and continuing lower overall vaccination coverage than other races. Determinants of this lower coverage are underexamined.MethodsAmong peer-reviewed relevant articles since 1968, 39 studied AIANs solely; 47 drew general population samples, including AIANs. We employed rigorous economic definitions and framework of Individual Decision-Making Under Uncertainty. The Social-Ecological model identified determinants and mechanisms at five levels.FindingsIndividual-level determinants include: (1) vaccine-preventable disease (VPD) and vaccine knowledge; (2) vaccine safety, efficacy, moral hazard beliefs; (3) preferences; (4) income and post-subsidy costs. Interpersonal-level determinants include others’ knowledge and preferences. Organizational-level characteristics of Indian Health Service, Tribal, Urban Indian (IHS/T/U) facilities include: (1) supply of vaccine products, providers, services; (2) provider cultural competency, vaccine recommendations, standing orders; (3) patient reminder/recall. Community-level characteristics include: (1) socioeconomics and geographics; (2) information infrastructure; (3) cultural values, practices, languages; (4) historical epidemic knowledge; (5) historical harms thus distrust in government, health system, science. Societal-level determinants include: (1) federal recognition and entitlements; (2) tribal self-determination; (3) state Medicaid enrollment; (4) structural racism.Policy recommendationsTribal interventions may (1) increase AIANs’ knowledge about VPDs, vaccines, Medicaid enrollment; (2) design risk/cost–benefit calculations using scientific objective probabilities of vaccine safety and efficacy; (3) tailor messages to epidemic histories, narratives, values; (4) outreach by trusted messengers. I/T/U organizational interventions may reduce transportation costs while increasing provider supplies, cultural competency, and vaccine standing orders. Federal policies may increase IHS funding, tribal infrastructure, and AIAN data representativeness while eliminating structural racism and generational trauma.ConclusionThis article contributes to literature and practice. It is the first multidisciplinary, comprehensive overview of multi-level determinants and mechanisms of AIAN vaccination. Its findings highlight the gaps and limitations of laws and policies impacting AIAN vaccination. It recommends future research, culturally-appropriate interventions, and policies to close the gap to enhance AIAN vaccination and healing.