bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low-level alcohol consumption and cancer mortality
Authors: Ko Hyeonyoung , Chang Yoosoo , Kim Han-Na , Kang Jae-Heon , Shin Hocheol , Sung Eunju , Ryu Seungho 
Published: February 2021

AbstractThe effect of light-to-moderate alcohol consumption on cancer risk remains controversial. We examined the association between low-level alcohol consumption and cancer mortality. A cohort study included 331,984 Korean adults free of cancer at baseline who underwent a comprehensive health checkup examination. Participants were categorized into never drinkers, former drinkers, and current drinkers who were further divided into light, moderate, heavy, and very heavy drinkers. Vital status and cancer-related deaths were ascertained through links to national death records. During 1,633,906 person-years of follow-up (median 5.3 years interquartile range 3.8–6.2), 374 cancer-related deaths were identified (cancer-cause mortality rate of 23 per 105 person-years). When former and never drinkers were classified as non-drinkers, the light drinkers had a lowest risk of cancer mortality compared with non-drinkers and other current drinkers (J-shaped); however, with consideration of lifetime abstinence history, current drinking was positively associated with cancer mortality in a dose-dependent manner. When changes in alcohol drinking status and confounders during follow-up were updated as time-varying covariates and never drinkers were used as the reference, the multivariable-adjusted hazard ratios (HRs) (95% confidence intervals, CIs) for cancer mortality among current light, moderate, heavy, and very heavy drinkers were 1.58 (1.03–2.43), 2.28 (1.41–3.70), 2.34 (1.42–3.85), and 2.97 (1.80–4.90), respectively, and the highest risk of cancer mortality was observed in former drinkers, who had an HR (95% CI) of 3.86 (2.38–6.28). Alcohol consumption was significantly and positively associated with an increased risk of cancer mortality in a dose-dependent manner, beginning with light drinkers.
Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
Authors: Buratta Sandra , Shimanaka Y. , Costanzi E. , Ni S. , Urbanelli L. , Kono N. , Morena F. , Sagini K. , Giovagnoli S. , Romani R. , Gargaro M. , Arai H. , Emiliani C. 
Published: February 2021

AbstractExtracellular vesicles (EVs) are well-known mediators in intercellular communication playing pivotal roles in promoting liver inflammation and fibrosis, events associated to hepatic lipotoxicity caused by saturated free fatty acid overloading. However, despite the importance of lipids in EV membrane architecture which, in turn, affects EV biophysical and biological properties, little is known about the lipid asset of EVs released under these conditions. Here, we analyzed phospholipid profile alterations of EVs released by hepatocarcinoma Huh-7 cells under increased membrane lipid saturation induced by supplementation with saturated fatty acid palmitate or Δ9 desaturase inhibition, using oleate, a nontoxic monounsaturated fatty acid, as control. As an increase of membrane lipid saturation induces endoplasmic reticulum (ER) stress, we also analyzed phospholipid rearrangements in EVs released by Huh-7 cells treated with thapsigargin, a conventional ER stress inducer. Results demonstrate that lipotoxic and/or ER stress conditions induced rearrangements not only into cell membrane phospholipids but also into the released EVs. Thus, cell membrane saturation level and/or ER stress are crucial to determine which lipids are discarded via EVs and EV lipid cargos might be useful to discriminate hepatic lipid overloading and ER stress.
Lifestyle is associated with atrial fibrillation development in patients with type 2 diabetes mellitus
Authors: Park Chan Soon , Han Kyung-Do , Choi Eue-Keun , Kim Da Hye , Lee Hyun-Jung , Lee So-Ryoung , Oh Seil 
Published: February 2021

AbstractWe evaluated the impacts of lifestyle behaviors, namely smoking, alcohol consumption, and physical activity, on the development of new-onset AF in patients with DM. Using the Korean Nationwide database, we identified subjects diagnosed with type 2 DM and without previous history of AF between 2009 and 2012. Self-reported lifestyle behaviors were analyzed. Among 2,551,036 included subjects, AF was newly diagnosed in 73,988 patients (median follow-up 7.1 years). Both ex-smokers (hazard ratio [HR] 1.05, 95% confidence interval [CI] 1.02–1.07) and current smokers (HR 1.06, 95% CI 1.03–1.08) demonstrated a higher risk of AF than never smokers. Patients with moderate (15–29 g/day) (HR 1.12, 95% CI 1.09–1.15) and heavy (≥ 30 g/day) (HR 1.24, 95% CI 1.21–1.28) alcohol consumption exhibited an increased risk of AF, while subjects with mild alcohol consumption (< 15 g/day) (HR 1.01, 95% CI 0.99–1.03) had an AF risk similar to that of non-drinkers. Patients who engaged in moderate-to-vigorous physical activity showed a lower risk of AF (HR 0.93, 95% CI 0.91–0.94) than those who did not. This study suggests that smoking, alcohol consumption, and physical activity are associated with new-onset AF in patients with DM, and lifestyle management might reduce the risk of AF in this population.
Ewe-lamb bond of experienced and inexperienced mothers undernourished during gestation
Authors: Freitas-de-Melo Aline , Pérez-Clariget Raquel , Terrazas Angélica , Ungerfeld Rodolfo 
Published: February 2021

AbstractThe aims were to compare ewe-lamb behaviours between primiparous (PRI) and multiparous (MUL) undernourished grazing ewes at birth and at 3 months of age, and to determine if mothers’ parity affects milk yield and composition, and lambs’ body weight (BW). Food availability restricted the nutritional requirements from day 30 to day 143 of gestation. The MUL ewes had greater BW than the PRI during gestation, and their lambs tended to vocalize less frequently until their first suckle. PRI ewes both displayed a lower frequency of acceptance behaviours and, a greater number of high-pitched bleats toward the alien lamb than toward that of their own, but MUL did not. PRI ewes produced less milk than the MUL ewes. The heart rate was greater in lambs reared by MUL ewes than by PRI. Although PRI ewes had a lower BW during gestation, this difference was stable throughout and did not affect the establishment of the ewe-lamb bond neither at birth nor at 3 months postpartum. At least under nutritionally restricted conditions during gestation, inexperienced mothers appeared to have had a shorter sensitivity period of maternal responsiveness than that of experienced mothers.
Spatiotemporal Control of Articulation During Speech and Speechlike Tasks in Amyotrophic Lateral Sclerosis
Authors: Rong Panying , Heidrick Lindsey 
Published: February 2021

PurposeThis study examined the articulatory control of speech and speechlike tasks in individuals with amyotrophic lateral sclerosis (ALS) and neurologically healthy individuals with the aim to identify the most useful set of articulatory features and tasks for assessing bulbar motor involvement in ALS.MethodTongue and jaw kinematics were recorded in 12 individuals with bulbar ALS and 10 healthy controls during a speech task and two speechlike tasks (i.e., alternating motion rate [AMR], sequential motion rate [SMR]). Eight articulatory features were derived for each participant per task, including the range, maximum speed, and acceleration time of tongue and jaw movements as well as the coupling and timing between tongue and jaw movements. The effects of task (i.e., AMR, SMR, speech) and group (i.e., ALS, control) on these articulatory features were evaluated. For each feature, the task that yielded the largest difference between the ALS and control groups was identified. The diagnostic efficacy of these task-specific features was assessed using the receiver operating characteristic analysis; the relation of these task-specific features to a well-established bulbar severity index—speaking rate—was determined using Spearman's rank correlation.ResultsSeven task-specific articulatory features were identified, including (a) tongue and jaw acceleration time during the AMR task, (b) tongue–jaw coupling during the SMR task, and (c) range of tongue movement, maximum tongue and jaw speed, and temporal lag between tongue and jaw movements during the speech task. Among these features, tongue and jaw acceleration time and their temporal lag showed relatively high accuracy (i.e., 0.83–0.95) in differentiating individuals with ALS from healthy controls. Range of tongue movement and maximum tongue and jaw speed showed significant correlations with speaking rate.ConclusionFindings provided preliminary evidence for the utility of task-specific articulatory measurements as a novel quantitative assessment to detect and predict bulbar motor involvement in ALS.
Massive OAM‐MIMO transmission scheme for 5G networks and beyond
Authors: Mao Fuchun , Ni Chunming , Zhang Zuoshan , Li Tinghua , Yang Chengfu , Zhang Jialin 
Published: February 2021

AbstractThe combination of orbital angular momentum (OAM) and massive multiple‐input multiple‐output (MIMO) brings the possibility of almost infinite transmission capability, which may be applied in the coming 5th generation networks and beyond. In this study, a uniform line array (ULA)‐based massive OAM‐MIMO scheme in a multipath scene is presented. The cumulative phase of OAM carriers and multiple reference coordinate systems relative to each transmitting antenna are used to describe the OAM‐MIMO wireless channel model theoretically. The performance indices of interest including capacity, energy efficiency, and capacity gain are numerically investigated in detail. The results indicate that the presented ULA‐based massive OAM‐MIMO scheme performs better overall than a conventional MIMO scheme via enhancing the OAM multiplexing intensity, and multi‐fold capacity gain can be obtained especially in the low signal‐to‐noise rate communications.
Noise‐enhanced quantum annealing approach and its application in plug‐in hybrid electric vehicle charging optimization
Authors: Xin Gang , Wang Peng , Jiao Yuwei 
Published: February 2021

AbstractA noise‐enhanced quantum annealing algorithm is proposed for an efficient annealing process to obtain the optimal solution. Simultaneous multiple noises are introduced as the kinetic energy term into the Schrödinger equation, which effectively reduces the probability of the algorithm falling into a local optimum by the parallel annealing process. The experimental results on the numerical optimisation problem and a real‐world plug‐in hybrid electric vehicles charging problem show that the proposed scheme is very competitive.
Human behaviour recognition with mid‐level representations for crowd understanding and analysis
Authors: Sun Bangyong , Yuan Nianzeng , Li Shuying , Wu Siyuan , Wang Nan 
Published: February 2021

AbstractCrowd understanding and analysis have received increasing attention for couples of decades, and development of human behaviour recognition strongly supports the application of crowd understanding and analysis. Human behaviour recognition usually seeks to automatically analyse ongoing movements and actions in different camera views by using various machine learning methodologies in unknown video clips or image sequences. Compared to other data modalities such as documents and images, processing video data demands much higher computational and storage resources. The idea of using middle level semantic concepts to represent human actions from videos is explored and it is argued that these semantic attributes enable the construction of more descriptive methods for human action recognition. The mid‐level attributes, initialized by a cluster processing, are built upon low level features and fully utilize the discrepancies in different action classes, which can capture the importance of each attribute for each action class. In this way, the representation is constructed to be semantically rich and capable of highly discriminative performance even paired with simple linear classifiers. The method is verified on three challenging datasets (KTH, UCF50 and HMDB51), and the experimental results demonstrate that our method achieves better results than the baseline methods on human action recognition.
Ascertaining Design Requirements for Postoperative Care Transition Interventions
Authors: Abraham Joanna , King Christopher R. , Meng Alicia 
Published: February 2021

Abstract
Background Handoffs or care transitions from the operating room (OR) to intensive care unit (ICU) are fragmented and vulnerable to communication errors. Although protocols and checklists for standardization help reduce errors, such interventions suffer from limited sustainability. An unexplored aspect is the potential role of developing personalized postoperative transition interventions using artificial intelligence (AI)-generated risks.
Objectives This study was aimed to (1) identify factors affecting sustainability of handoff standardization, (2) utilize a human-centered approach to develop design ideas and prototyping requirements for a sustainable handoff intervention, and (3) explore the potential role for AI risk assessment during handoffs.
Methods We conducted four design workshops with 24 participants representing OR and ICU teams at a large medical academic center. Data collection phases were (1) open-ended questions, (2) closed card sorting of handoff information elements, and (3) scenario-based design ideation and prototyping for a handoff intervention. Data were analyzed using thematic analysis. Card sorts were further tallied to characterize handoff information elements as core, flexible, or unnecessary.
Results Limited protocol awareness among clinicians and lack of an interdisciplinary electronic health record (EHR)-integrated handoff intervention prevented long-term sustainability of handoff standardization. Clinicians argued for a handoff intervention comprised of core elements (included for all patients) and flexible elements (tailored by patient condition and risks). They also identified unnecessary elements that could be omitted during handoffs. Similarities and differences in handoff intervention requirements among physicians and nurses were noted; in particular, clinicians expressed divergent views on the role of AI-generated postoperative risks.
Conclusion Current postoperative handoff interventions focus largely on standardization of information transfer and handoff processes. Our design approach allowed us to visualize accurate models of user expectations for effective interdisciplinary communication. Insights from this study point toward EHR-integrated, “flexibly standardized” care transition interventions that can automatically generate a patient-centered summary and risk-based report.
Are We Ready for Video Recognition and Computer Vision in the Intensive Care Unit? A Survey
Authors: Glancova Alzbeta , Do Quan T. , Sanghavi Devang K. , Franco Pablo Moreno , Gopal Neethu , Lehman Lindsey M. , Dong Yue , Pickering Brian W. , Herasevich Vitaly 
Published: February 2021

AbstractObjective Video recording and video recognition (VR) with computer vision have become widely used in many aspects of modern life. Hospitals have employed VR technology for security purposes, however, despite the growing number of studies showing the feasibility of VR software for physiologic monitoring or detection of patient movement, its use in the intensive care unit (ICU) in real-time is sparse and the perception of this novel technology is unknown. The objective of this study is to understand the attitudes of providers, patients, and patient's families toward using VR in the ICU.Design A 10-question survey instrument was used and distributed into two groups of participants: clinicians (MDs, advance practice providers, registered nurses), patients and families (adult patients and patients' relatives). Questions were specifically worded and section for free text-comments created to elicit respondents' thoughts and attitudes on potential issues and barriers toward implementation of VR in the ICU.Setting The survey was conducted at Mayo Clinic in Minnesota and Florida.Results A total of 233 clinicians' and 50 patients' surveys were collected. Both cohorts favored VR under specific circumstances (e.g., invasive intervention and diagnostic manipulation). Acceptable reasons for VR usage according to clinicians were anticipated positive impact on patient safety (70%), and diagnostic suggestions and decision support (51%). A minority of providers was concerned that artificial intelligence (AI) would replace their job (14%) or erode professional skills (28%). The potential use of VR in lawsuits (81% clinicians) and privacy breaches (59% patients) were major areas of concern. Further identified barriers were lack of trust for AI, deterioration of the patient–clinician rapport. Patients agreed with VR unless it does not reduce nursing care or record sensitive scenarios.Conclusion The survey provides valuable information on the acceptance of VR cameras in the critical care setting including an overview of real concerns and attitudes toward the use of VR technology in the ICU.
Поэма А. Блока « Двенадцать » в чешской среде
Authors: Kitzlerová Jana 
Published: February 2021

Abstract
This paper consists of confrontational analysis of two Czech translations of Alexander Blok’s famous poem “The
Twelve”: one by Bohumil Mathesius published in 1925 (4th ed. 1977) which was considered canonical for many generations of Czech readers; and the most recent one published
by Lubor Kasal in 2016. The present study tries to ascertain which translation is more accurate and closer to the Russian original
and to identify the flaws and mistakes from the stylistic and semantic point of view which can be found in both translations.
The paper discusses whether the two Czech translations under study render the same aesthetic experience for Czech readers as the
original for its Russian readers. Both translations are closely examined with emphases on several important aspects: the semantic
density of both the original and the Czech translations; the rhythm of the Russian poem and of its Czech versions; the
choice of suitable equivalents in both translations. In the end, the assessment of Lubor Kasal’s Czech translation is overall
positive, as it meets the requirements for the translator and his translation without serious reservations.
Wollastonite (CaSiO3)-based Composite Particles for Synthetic Food Dyes (Brilliant Blue) Removal in Aquatic Media: Synthesis, Characterization and Kinetic study
Authors: Ernawati Lusi , Wahyuono Ruri Agung , Laksono Andromeda Dwi , Ningrum Andriati , Handayani Kurnia , Sabrina Audi 
Published: February 2021

Abstract
We report a facile and environmentally friendly solid-state method to prepare mesoporous wollastonite (calcium silicate, CaSiO3) based composite adsorbent from chicken eggshells and SiO2 powder as starting materials for food dyes removal, i.e. brilliant blue. The CaSiO3 particles were prepared using CaCO3/SiO2 molar ratio of 1:5 and 2:5 and calcined at 1100°C. The physicochemical properties of adsorbent were characterized by SEM-EDX, XRD, BET-BJH, and FTIR analysis whilst the adsorbent performance was assessed for 100 ppm aqueous brilliant blue removal. The obtained CaSiO3 shows single-phase hexagonal structure and the morphology was in irregular shape as revealed by scanning electron micrograph. In addition, the CaSiO3 adsorbent shows specific surface area of 3.053 m2 g−1 and a small pore diameter of 1.52 nm. The dye removal test indicates that maximum adsorption capacity of the dye molecules onto CaSiO3 particles is approximately 173 mg g-1. The adsorption kinetics fit well with the pseudo-second order model while the adsorption equilibrium fits best the Langmuir model. In general, the prepared CaSiO3 composite here is promising for dye removal in contaminated aqueous solution.
Study of waste tyre granulates and polypropylene (PP) fibre as oil sorbent
Authors: Lah Nik Khairul Irfan Nik Ab , Zahid Muhammad Naqiuddin , Fuad Mohd Fazril Irfan Ahmad , Mohd Tengku Amran Tengku , Japperi Nur Shuhadah 
Published: February 2021

Abstract
There were various types of sorbent materials that exist in the current market that dealing with the oil spill incidents. However, because of high cost and incapable of repeated use, make it harder to combating oil spillage effectively and to suite environment friendly material. This study was done to assess waste tyre granulates and polypropylene (PP) fibre as oil sorbent in terms of its capacity, different type of oil absorbs and durability. Two different types of oil where used in this study in measuring the durability of the materials which are diesel and used engine oil. The sorbent capacity and re-usability tests were used to evaluate the practical sorption of each material. From the result it was found that waste tyre granulates had low oil practical sorption than PP fibre with almost 50% different. However, waste tyre granulates had high elasticity compared to PP fibre which enable it to be used repeatedly without losing its oil sorption capability. Therefore, both waste tyre granulates and PP fibre were combined to develop a new composite material sorbent that capable of recovering greater amounts of oil than using waste tyre granulates alone. The result shows that these composite material sorbent can be used repeatedly for at least 25 times.
Simulation study of engineered Integral-Layer with Solid-Skin structure in Microcellular Polystyrene Foam using Superheat-Induced-Foaming method
Authors: Adam Fajar Firstya , Baggery Calvin , Samuel Jeremy , Trisanti Prida Novarita , Sumarno  
Published: February 2021

Abstract
Microcellular plastic foam can be formed by the so-called superheat-induced-foaming method, which known as solid-state foaming process. This process involves the dissolution of the blowing agent (CO2) in polystyrene and foaming the gas-laden polystyrene by induction the superheat on it. This process utilizes the effect of plasticization due to dissolved blowing agent in polystyrene matrices. An interval time which desorption of CO2 occurs, definitely after dissolution CO2 in polystyrene prior the foaming process, would make it is possible to develop the integral layer which consists of transition-cellular-core and solid-skin layer by manipulating the desorption time. In the present study, the solid-skin and integral-core-layer formation is simulated by considering the heat and mass transfer model to predict the solid-skin thickness and classical nucleation theory to predict the amount of cell density. It is concluded that with an increase of desorption time, the solid-skin is thicker, and the cell density is lower, compared with the lower desorption time, thinner solid-skin is obtained. Whereas, an increase in foaming temperature, thinner solid-skin with higher cell density is predicted contrary with lower foaming temperature. Additionally, in this study, the predicted cell nucleation is validated to the experimental results with sum-squared-error about 7.248.