bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lesión pulmonar asociada al vapeo
Authors: Rojas Mora Erick José , Delgado Castro Liseth Gabriela , Fung Fallas Michelle Pamela 
Published: October 2021

El vapeo o el uso de cigarrillos electrónicos es una tendencia que ha aumentado en los últimos años, afectando principalmente a jóvenes; produciendo una lesión pulmonar de la cual todavía no se tiene conocimiento exacto, sin embargo se ha correlacionado con un tipo de neumonitis aguda. Hasta la fecha, se desconoce cuál de todas las sustancias que contienen esos productos es la causante de la injuria; el acetato de vitamina E es hasta el momento la principal que ha sido asociada al daño, empero se ocuparán más estudios en las poblaciones afectadas para conocer más sobre la fisiopatología de esta enfermedad.
Future scenarios of rice brown plant hopper Nilaparvata lugens (Stal.) under changing climate
Authors: S. VENNILA  , SHABISTANA NISAR  , A. ISLAM  , SANJAY SHARMA  , P.S. SARAO  , ANANDHI P.  , M.SRINIVASA RAO  , M. PRABHAKAR  
Published: October 2021

Abundance of brown plant hopper (BPH) Nilaparvatalugens (Stål) (Delphacidae: Homoptera) is modulated by prevalent weather conditions of rice growing seasons and locations. Categorization of BPH adults caught in light traps (nos/week/trap) into low, moderate and high and formulation of criteria accounting weather variables [maximum/ minimum/ mean temperature (ÚC), morning/evening/mean relative humidity (%), rainfall (mm) and sunshine hours (h/day) and wind speed (km/h)] during kharif of2011-16 for four locations viz., Ludhiana (Punjab), Chinsurah (West Bengal), Raipur (Chhattisgarh) and Aduthurai (Tamil Nadu) with associated rules for weather based BPH prediction. Validation of BPH predictions for kharif 2017 indicated 96, 87, 73 and 61% accuracies in respect of Aduthurai (TN), Raipur (CG), Ludhiana (PB) and Chinsurah (WB). Future weather based predictions of BPH based on climatic projections of representative concentration pathway (RCP) 4.5 for 2020, 2050 and 2080 indicated absence of high population at Chinsurah (WB) during all time periods of 2020-2080. Progressively reducing BPH abundance from past (2011) to all future periods was noticed at Aduthurai (TN). ‘High’ BPH from 2020 and beyond over 2011 and 2016 at Raipur (CG) and reducing ‘high’ but increasing ‘moderate’ category between 2020-2050 but the reverse in 2080 at Ludhiana (PB) were predicted indicating requirement of continued monitoring strategies put in place at these locations. The observed spatial variability of climate change influence on BPH implied a need for zonation mapping of rice insects including BPH for India.
Wheat yield prediction in relation to climatic parameters using statistical model for Ludhiana district of central Punjab
Authors: MAHESH CHAND SINGH  , VAJINDER PAL  , SOM PAL SINGH  , SANJAY SATPUTE  
Published: October 2021

Climate change which is one of the main determinants of agricultural production has started affecting the crop growth pattern and yield from past couple of decades in various agro-climatic zones globally. Under such scenario, the prior forecasting of yield of field crops such as wheat via modeling techniques can help in simplifying the crop production management system starting from farmer’s level to policy makers. The present study was thus undertaken to model the wheat yield of Ludhiana district of Indian Punjab through regression analysis of historical data (1993-2017) of wheat yield and climatic conditions in the area. The developed model was successfully validated with a strong positive correlation (R2=0.81) between predicted and observed data. Both observed and predicted yields were having similar trend with a minimum and maximum absolute differential error of 0.1 and 13.9% respectively. The developed model may serve as a powerful tool for predicting the future yield of wheat crop with available futuristic climatic data of the study area.
Case Study of Bacterial Decontamination of an Aromatic and Medicinal Plant: Decontamination of Thymus Satureioides by Gamma Radiation at Low Doses and Impact on Hygienic and Physicochemical Quality
Authors: Mostafa Mahrouz , Lamyae Lahnine , Safa Mghazli , Ouhammou Mourad , Mouhib Mohammed , Ali Misdaq Moulay 
Published: October 2021

The purpose of our study is to verify the usefulness of gamma irradiation treatment at low doses (0.25, 0.5 and 1 kGy) combined to vacuum packaging on commercial teas of Thymus satureioides deliberately contaminated with Escherichia coli. The efficiency and the influence of the process on contamination level and the shelf life of the product were studied. The phenolic composition and concentration were identified in the unirradiated and irradiated thyme. The total phenolic content (TPC) was assayed by the Folin-Ciocalteu method, the individual phenolic compounds were determined by high liquid chromatography (HPLC) and the essential oil was characterized by gas chromatography coupled to mass spectroscopy (GC-MS). The plant was observed by scanning electrons microscopy and the radioactivity effect was analyzed. The results show a complete decontamination of thyme depending to the dose and the storage time. Privileged hygienic quality was found in the irradiated thyme with the highest concentrations of polyphenols. The process showed the conservation of thyme quality without any alteration of its characteristics or radioactivity effect.
Some Folk Antidiabetic Medicinal Herb of Himachal Pradesh
Authors: Rana Monika , Rana Meenakshi 
Published: October 2021

The Prevalence of Diabetes Mellitus (DM) is increasing day by day at an alarming worldwide. As per the statics of International Diabetic Federation, currently worldwide approximately 463 million adults (20–79 years) affected with diabetes that is expected to increase rise to 700 million by 2045. Diabetes and its complications imposes an economic loss to people with diabetes and their families, and to health systems and national economy. Diabetes is a complex disease which link with multiple of factors. Present reviewdocument the information of traditional used Antidiabetic plants by the inhabitants of Nadaun, District Hamirpur, Himachal Pradesh, India. During the survey 31 Medicinal Plants have been documented on the basis of information collected from the respondents of the study area.
Land-use change influence soil quality parameters at an ecologically fragile area of YongDeng County of Gansu Province, China
Authors: Adingo Samuel , Yu Jie-Ru , Xuelu Liu , Jing Sun , Li Xiaodan , Xiaoning Zhang 
Published: October 2021

Dry ecosystems, despite their relative levels of aridity, are very diverse, and play a vital role in the livelihoods of many dryland inhabitants. It is therefore critical to investigate the relationship between land-use change and soil quality parameters to offer a scientific basis for optimizing land-use planning and improving soil quality status in dry ecosystems and ecologically vulnerable areas. This study, therefore, analyzed the physicochemical properties of soils in five different land-use types namely farmland, abandoned farmland, natural grassland, artificial lemon forest, and poplar woodland at YongDeng County. The soil quality status of the aforementioned land-use types was also evaluated through Principal component analysis. The results revealed that abandoned farmland and natural grassland recorded the highest average values of soil coarse particles of 24.0% and 23.4% respectively compared to the other land-use types. The highest average value (46.1%) of fine soil particles was recorded in poplar woodland followed by natural grassland (36.6%) and the average value of very fine soil particles was higher in farmland (40.8%) and artificial lemon woodland (38.3%) than in the other land-use types. The average value of clayey particles was highest in farmland (11.1%), followed by artificial lemon woodland (9.3%), and abandoned farmland (6.5%), then poplar woodland which recorded an average value of (4.2%). The average values of Soil water content, soil pH, soil electrical conductivity, and soil total nitrogen content were significantly higher in farmland compared to the other land-use types. Soil organic carbon content was significantly higher in abandoned farmland at (P < 0.03) and lemon woodland at (P < 0.01) than in farmlands, natural grasslands, and poplar stands. The soil quality indicators of the different land-use types were significantly correlated with each other. Among them, the correlation coefficient of each evaluation index was highest in poplar woodland, followed by natural grassland, lower in farmland and artificial lemon woodland, and lowest in abandoned farmland. The overall soil quality scores were in the following order: farmland > abandoned farmland > 0 > grassland > lemon woodland > poplar woodland. In the study area, the soil quality of farmland that has been finely managed and naturally restored to grassland following abandonment is superior, whereas the soil quality of natural grassland, artificial lemon woodland, and poplar forest land is substandard. The comprehensive analysis of soil quality demonstrates that conservation tillage and fine management of water-irrigated farmland, as well as the natural conversion of abandoned farmland to grassland, can significantly improve the soil quality of sandy soils, reduce water and soil loss, increase fertility, and gradually improve regional ecological environmental conditions.
In vitro induction and identification of polyploid Neolamarckia cadamba plants by colchicine treatment
Authors: Eng Wee Hiang , Ho Wei Seng , Ling Kwong Hung 
Published: October 2021

Polyploidization has played a crucial role in plant breeding and crop improvement. However, studies on the polyploidization of tropical tree species are still very scarce in this region. This paper described the in vitro induction and identification of polyploid plants of Neolamarckia cadamba by colchicine treatment. N. cadamba belongs to the Rubiaceae family is a natural tetraploid plant with 44 chromosomes (2n = 4x = 44). Nodal segments were treated with colchicine (0.1%, 0.3% and 0.5%) for 24 h and 48 h before transferring to shoot regeneration medium. Flow cytometry (FCM) and chromosome count were employed to determine the ploidy level and chromosome number of the regenerants, respectively. Of 180 colchicine-treated nodal segments, 39, 14 and 22 were tetraploids, mixoploids and octoploids, respectively. The highest percentage of polyploidization (20% octoploids; 6.7% mixoploids) was observed after treated with 0.3% colchicine for 48 h. The DNA content of tetraploid (4C) and octoploid (8C) was 2.59 ± 0.09 pg and 5.35 ± 0.24 pg, respectively. Mixoploid plants are made up of mixed tetraploid and octoploid cells. Chromosome count confirmed that tetraploid cell has 44 chromosomes and colchicine-induced octoploid cell has 88 chromosomes. Both octoploids and mixoploids grew slower than tetraploids under in vitro conditions. Morphological characterizations showed that mixoploid and octoploid leaves had thicker leaf blades, thicker midrib, bigger stomata size, lower stomata density, higher SPAD value and smaller pith layer than tetraploids. This indicates that polyploidization has changed and resulted in traits that are predicted to increase photosynthetic capacity of N. cadamba. These novel polyploid plants could be valuable resources for advanced N. cadamba breeding programs to produce improved clones for planted forest development.
Antileishmanial Activity of Cassia fistula L., Morus nigra L. and Ziziphus jujuba Mill., Plant Extracts
Authors: Iqbal Kashif , Dar Eshwa , Shaikh Abdul Rashid , Akhtar Samar , Marvi . 
Published: October 2021

Aim: To investigate the different antileishmanial activities of extracts of Cassia Fistula L., Morus Nigra L. and Ziziphus Jujuba Mill.
Methodology: In this method, three (03) plants having concentrations between 500 – 2000 µg/mL were subjected to KWH23 strains of L. tropica in which Standard drug was Amphotericin B and have negative control for 24 – 48 hours. To check the in-vivo studies, plant extract was tested on BALB/c mice (Iqbal et al., 2016).
Results: It showed that inhibition (mean) of KWH23 strains at 500, 1000, 1500, 2000 µg/mL after 48 hours were 92.1 ± 0.02, 95.00 ± 0.05, 97.09 ± 0.07 and 98.05 ± 0.05 % respectively. It decreased the lesion size (mean) from 0.8 ± 0.1 mm to 0.40 ± 0.2 mm having significance value p < 0.01 after 8th week, and cure at 200 mg/Kg against intracellular amastigotes in BALB/c mice was 90.00% (95% Cl = 80.05 – 97.00).
Conclusion: The result shows that Ziziphus jujuba Mill. leaves possess significant antileishmanial activity.
Antifungal Activity of Flavonoid Isolated from Lindernia crustacea (L) F. Muell against Traditionally Claimed Dermatophytes
Authors: Chanda Das Smriti Rekha , Ahmed Abdul Baquee , Shil Dibyendu , Das Trishna , Alam Faruk , Chakraborty Jashabir 
Published: October 2021

Aim: The present study was aimed to establish antifungal activity of flavonoid isolated from Lindernia crustacea (L) F. Muell.
Methods: Potent bioactive constituent from benzene extract was isolated through flash chromatography with solvent Toluene and Acetic acid (4:1). Isolated compound was structurally established by spectroscopic method. Antifungal potential of benzene extract as well as isolated compound was tested by disc diffusion method against two fungal strains Candida albicans (C. albicans) and Trichophyton rubrum (T. rubrum).
Results: The isolated compound from benzene extract was found to be flavonoid. Benzene extract as well as flavonoid were shown remarkable zone of inhibition against both fungal strains which indicates strong antifungal activity.
Conclusion: The experimental results concluded that Lindernia crustacea (L) F. Muell have significant anti fungal activity due to flavonoid content. It is expected that the results of the present research work would be beneficial in establishing the scientific basis of the traditional claims of medicinal values of Lindernia crustacea.
Eradication of Malaria: Present Situations and New Strategies
Authors: Alsulami Muslimah N. 
Published: October 2021

Malaria is a serious disease caused by the protozoon parasite Plasmodium and transmitted by the female Anopheles mosquito as a vector. P. falciparum is the gravest infection for all other species P. ovale, P. vivax, P. Malariae and P. knowlesi in terms of morbidity or mortality, which is why most research focused on P. falciparum. The disease affects about 300-500 million people, mostly in the tropics. In regions with a weak economic downturn in tropical and subtropical capital, morbidity and mortality have elevated. Malaria remains a persistent threat in recent research. At the beginning of the 20th century, scientists tried to describe a successful way of eradicating malaria. However, the presence of drug resistance and social and environmental problems, no acceptable and positive future solution has been pointed out. Several studies have highlighted the need to establish advanced nano-biotechnology treatment, novel anti-malarial drug targets, an efficient malaria vaccine technique, and Anopheles gene editing, which opened the door to a healthy, environmentally friendly malaria treatment method over the last two decades. In recent years, the use of mosquito microbiota has shown great potential for cutting down the transmission of mosquito-borne pathogens. This review aims to cover important issues in malarial eradication as rapid diagnostic technology, novel anti-malarial drug targets, Anopheles gene editing, use of mosquito microbiota, and recent vaccines.
Structured groups make more accurate veracity judgements than individuals
Authors: Hamlin Iain , Bolger Fergus , Vasilichi Alexandrina , Belton Ian , Crawford Megan M. , Sissons Aileen , Taylor Browne Lūka Courtney , Wright George 
Published: October 2021

AbstractGroups often make better judgements than individuals, and recent research suggests that this phenomenon extends to the deception detection domain. The present research investigated whether the influence of groups enhances the accuracy of judgements, and whether group size influences deception detection accuracy. Two‐hundred fifty participants evaluated written statements with a pre‐established detection accuracy rate of 60% in terms of veracity before viewing either the judgements and rationales of several other group members or a short summary of the written statement and revising or restating their own judgements accordingly. Participants' second responses were significantly more accurate than their first, suggesting a small positive effect of structured groups on deception detection accuracy. Group size did not have a significant effect on detection accuracy. The present work extends our understanding of the utility of group deception detection, suggesting that asynchronous, structured groups outperform individuals at detecting deception.
Organic Thin‐Film Transistors as Cannabinoid Sensors: Effect of Analytes on Phthalocyanine Film Crystallization
Authors: Comeau Zachary J. , Rice Nicole A. , Harris Cory S. , Shuhendler Adam J. , Lessard Benoît H. 
Published: October 2021

AbstractWith a growing international trend of Cannabis legalization, there is a present need for on‐the‐spot, low cost, and rapid detection of cannabinoids. Here, relationships between thin‐films of phthalocyanines (Pcs) with a variety of central, peripheral, and axial substituents and their response to the cannabinoid Δ9‐tetrahydrocannabinol (THC), with and without a cannabinoid‐sensitive chromophore (Fast Blue BB) are investigated through organic thin‐film transistor (OTFT) performance. X‐ray diffraction and UV–vis absorption spectroscopy measurements demonstrate significantly altered film morphologies and the formation of new crystal orientations in response to analytes, which are corroborated by scanning electron microscopy. Electron paramagnetic resonance further corroborates shifting crystal structures in response to THC and also reveals the formation and promotion of Pc radical species through THC‐metal coordination. With exposure to THC, aluminum chloride Pc generates the largest physical film changes as well as the largest changes in OTFT performance. These findings suggest that the semiconductor thin‐film morphologies in Pc‐based OTFT sensors are not static in the presence of analytes and that the sensing response is driven both by strong analyte‐Pc coordination and bulk film restructuring to accommodate these interactions.
Highly‐Tunable Intrinsic Room‐Temperature Ferromagnetism in 2D van der Waals Semiconductor CrxGa1−xTe
Authors: Zhang Gaojie , Wu Hao , Zhang Liang , Zhang Shanfei , Yang Li , Gao Pengfei , Wen Xiaokun , Jin Wen , Guo Fei , Xie Yuanmiao , Li Hongda , Tao Boran , Zhang Wenfeng , Chang Haixin 
Published: October 2021

AbstractThe combination of semiconductivity and tunable ferromagnetism is pivotal for electrical control of ferromagnetism and next‐generation low‐power spintronic devices. However, Curie temperatures (TC) for most traditional intrinsic ferromagnetic semiconductors (≤200 K) and recently discovered two‐dimensional (2D) ones (<70 K) are far below room temperature. 2D van der Waals (vdW) semiconductors with intrinsic room‐temperature ferromagnetism remain elusive considering the unfavored 2D long‐range ferromagnetic order indicated by Mermin–Wagner theorem. Here, vdW semiconductor CrxGa1−xTe crystals exhibiting highly tunable above‐room‐temperature ferromagnetism with bandgap 1.62–1.66 eV are reported. The saturation magnetic moment (Msat) of CrxGa1−xTe crystals can be effectively regulated up to ≈5.4 times by tuning Cr content and ≈75.9 times by changing the thickness. vdW CrxGa1−xTe ultrathin semiconductor crystals show robust room‐temperature ferromagnetism with the 2D quantum confinement effect, enabling TC 314.9–329 K for nanosheets, record‐high for intrinsic vdW 2D ferromagnetic semiconductors. This work opens an avenue to room‐temperature 2D vdW ferromagnetic semiconductor for 2D electronic and spintronic devices.
Computational study of planar extrudate swell flows with a viscous liquid–gas interface
Authors: Mendes Junior Paulo Roberto C. , Siqueira Ivan R. , Thompson Roney L. , Carvalho Marcio S. 
Published: October 2021

AbstractWe present a computational study of planar extrudate swell flows of Newtonian liquids with a viscous liquid–gas interface. The model consists of the equations of motion coupled with the Boussinesq–Scriven constitutive equation for the interfacial stress tensor. The resulting set of equations is solved with the finite element method coupled with an elliptic mesh generation strategy to capture the free surface. The results show a detailed parametric study in terms of the capillary number and the Boussinesq number, a dimensionless parameter used to measure the ratio of viscous forces at the interface to viscous forces in the bulk liquid. The predictions reveal that the extrudate swells dramatically as the interfacial viscosity grows. The interfacial viscosity slows down the flow both in the bulk liquid and at the interface, and thus the extrudate size increases to conserve mass in the slow plug flow that develops under the free surface.
Long‐term outcomes in patients with advanced and/or metastatic non–small cell lung cancer who completed 2 years of immune checkpoint inhibitors or achieved a durable response after discontinuation without disease progression: Multicenter, real‐world data (KCSG LU20‐11)
Authors: Kim Hongsik , Kim Dong‐Wan , Kim Miso , Lee Youngjoo , Ahn Hee Kyung , Cho Jang Ho , Kim Il Hwan , Lee Yun‐Gyoo , Shin Seong‐Hoon , Park Song Ee , Jung Jiyoon , Kang Eun Joo , Ahn Myung‐Ju 
Published: October 2021

BackgroundImmune checkpoint inhibitors (ICIs) have shown significant improvements in patients with advanced non–small cell lung cancer (NSCLC). One of the major issues with ICIs is determining the optimal treatment duration.MethodsThis multicenter, retrospective study analyzed clinical outcomes in patients with NSCLC who completed 2 years of ICI therapy or were treated for more than 6 months and then discontinued ICIs without disease progression at 11 medical centers in Korea between August 2017 and December 2020.ResultsNinety‐six patients who completed 2 years of ICIs were reviewed. The median durations of treatment and follow‐up were 24.0 and 33.9 months, respectively. The objective response rate (ORR) was 85.4%. The median progression‐free survival (PFS) and overall survival (OS) periods were not reached. After completion, the PFS and OS rates were 81.1% and 96.4%, respectively, at 12 months. Forty‐three patients were identified who discontinued ICIs without disease progression: 26 (60.5%) for adverse events and 17 (39.5%) for other causes. The median durations of treatment and follow‐up were 10.5 and 21.2 months, respectively. The ORR was 90.7%. The median PFS and OS periods were not reached. After discontinuation, the PFS and OS rates were 71.0% and 90.0%, respectively, at 12 months.ConclusionsA significantly high proportion of patients who completed 2 years of ICI therapy continued to experience long‐term PFS. Even if ICIs are discontinued after 6 months in patients without disease progression, they may achieve a durable response and facilitate long‐term survival.Lay Summary

The optimal treatment duration for immune checkpoint inhibitors (ICIs) remains to be determined.

This study reports the long‐term outcomes of patients with non–small cell lung cancer who completed 2 years of ICI therapy or achieved a durable response after the discontinuation of ICIs without disease progression in real‐world practice.

A significantly high proportion of patients who completed 2 years of ICIs continued to experience long‐term progression‐free survival.

In addition, even if ICIs are discontinued after 6 months in patients without disease progression, they may achieve a durable response and facilitate long‐term survival.