bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating equity, diversity, and inclusion into social innovation education: a case study of critical service-learning
Authors: Otten Rebecca , Faughnan Máille , Flattley Megan , Fleurinor Samantha 
Published: July 2021

Purpose
Social innovation education aims to equip students with the skills and mindsets to pursue sustainable and just solutions to complex challenges, yet many programs fail to address the power dynamics underlying unjust social structures. This paper aims to examine a social innovation course that integrates equity, diversity and inclusion principles through critical service-learning.

Design/methodology/approach
Researchers conducted semi-structured interviews of 25 students and 5 key informants in a qualitative, single case design to understand multiple perspectives on significant factors in transformative learning. Document review and auto-ethnographic insights provide additional case background.

Findings
Students identified the service experience as unique and high impact. Significant factors included the atypical service structure, the EDI framework, and the partner organization as an exemplar in the field. Students displayed a spectrum of learning, from recall and comprehension to critical evaluation, new worldviews, and behavior change.

Research limitations/implications
The findings of this qualitative study pertain to one partnership but are generalizable to theories. These findings are plausibly transferable to other experiential social innovation courses embedded in elite, private, predominately white research universities.

Originality/value
This empirical case examines a unique pedagogical and curricular innovation. By seeking to understand factors and outcomes of experiential learning, this study contributes to the literature on social innovation education and critical service-learning. The analysis produced novel insights for faculty and institutions aiming to integrate equity, diversity, and inclusion goals into social innovation programs.
Response of foliar mineral nutrients to long‐term nitrogen and phosphorus addition in a tropical forest
Authors: Mo Qifeng , Wang Wenjuan , Lambers Hans , Chen Yiqun , Yu Shiqin , Wu Chunsheng , Fan Yingxu , Zhou Qing , Li Zhi’an , Wang Faming 
Published: July 2021

Abstract

Mineral nutrients play a pivotal role in plant growth, development and reproduction. The uptake and distribution of nutrients are generally limited by soil nutrient availability, affected by global change. However, the responses of foliar mineral nutrient concentrations to changes in soil nutrient availability remain largely untested in tropical forests.

We used a field‐based experiment with nitrogen (N) and phosphorus (P) addition in a tropical forest in southern China to investigate the effect of N and P fertilization on exchangeable soil and foliar mineral nutrients of five understorey species.

Our results show that N addition did not change soil pH, but reduced exchangeable soil Ca2+, Mg2+, Zn2+, Fe3+ and Mn2+ concentrations. In contrast, P addition increased soil pH, while it had no effects on exchangeable cations. Nitrogen addition significantly decreased foliar [Ca], [Mg] and [Mn], while P addition markedly reduced foliar [Cu] for most of the studied species. Foliar [K] and [Fe] were not affected by fertilization. The results indicate that long‐term N addition reduced the concentrations of several mineral nutrients in leaves, and we did not observe any adaptive mechanisms (e.g. increased transpiration to take up mobile soil nutrients) in the studied species to maintain foliar nutrient concentrations at high N supply.

Synthesis. The responses of other foliar nutrient concentrations to N and P co‐addition were more complicated than those of N and/or P, and the specific decreases in mineral nutrient concentrations following long‐term N addition may influence key physiological process in the studied tropical understorey species, and ultimately reduce their fitness and survival under high N deposition.

A free Plain Language Summary can be found within the Supporting Information of this article.
Coastal wetland management in the Great Barrier Reef: Farmer perceptions
Authors: Oza Tanvi Mihir , Lane Ruth , Adame Maria Fernanda , Reef Ruth 
Published: July 2021

AbstractPoor water quality caused by intensive sugarcane farming has been among the main causes of coastal degradation around the Great Barrier Reef (GBR). Despite regulations and incentives, water quality in the GBR has yet to reach government targets, and there is an urgent need to investigate alternative management approaches. In this study, we have employed a social‐ecological approach to understand farmers' attitudes to existing nutrient and sediment management approaches, assess farmers' perceptions of managing coastal wetlands to ameliorate agricultural run‐off, and propose how these findings could inform integrative policy development for the GBR. We conducted semi‐structured interviews with sugarcane farmers in the Wet Tropics to understand perceptions of ecosystem services, coastal wetlands and industry challenges. We linked our analysis of key issues of concern to farmers with broader environmental and land use issues and have outlined future policy considerations in the face of socio‐economic and climatic change. Our conclusions emphasise the need to rethink future land tenure in low‐lying areas of North Queensland, the importance of considering ecosystem services provided by coastal wetlands in policy models and the need for a payments for ecosystem services (PES) model to safeguard the future of the GBR.
The design and application of a 50 K SNP chip for a threatened Aotearoa New Zealand passerine, the hihi
Authors: Lee Kate D. , Millar Craig D. , Brekke Patricia , Whibley Annabel , Ewen John G. , Hingston Melanie , Zhu Amy , Santure Anna W. 
Published: July 2021

AbstractNext‐generation sequencing has transformed the fields of ecological and evolutionary genetics by allowing for cost‐effective identification of genome‐wide variation. Single nucleotide polymorphism (SNP) arrays, or “SNP chips”, enable very large numbers of individuals to be consistently genotyped at a selected set of these identified markers, and also offer the advantage of being able to analyse samples of variable DNA quality. We used reduced representation restriction‐aided digest sequencing (RAD‐seq) of 31 birds of the threatened hihi (Notiomystis cincta; stitchbird) and low‐coverage whole genome sequencing (WGS) of 10 of these birds to develop an Affymetrix 50 K SNP chip. We overcame the limitations of having no hihi reference genome and a low quantity of sequence data by separate and pooled de novo assembly of each of the 10 WGS birds. Reads from all individuals were mapped back to these de novo assemblies to identify SNPs. A subset of RAD‐seq and WGS SNPs were selected for inclusion on the chip, prioritising SNPs with the highest quality scores whose flanking sequence uniquely aligned to the zebra finch (Taeniopygia guttata) genome. Of the 58,466 SNPs manufactured on the chip, 72% passed filtering metrics and were polymorphic. By genotyping 1,536 hihi on the array, we found that SNPs detected in multiple assemblies were more likely to successfully genotype, representing a cost‐effective approach to identify SNPs for genotyping. Here, we demonstrate the utility of the SNP chip by describing the high rates of linkage disequilibrium in the hihi genome, reflecting the history of population bottlenecks in the species.
Dramatic response to alectinib in a patient with ALK‐rearranged squamous cell lung cancer
Authors: Shiihara Jun , Ohyanagi Fumiyoshi , Amari Hikari , Toda Minemichi , Tahara Hiroki , Yuzawa Motoi , Maeda Yuki , Nomura Motoko , Mizushina Yoshiko , Nagai Yoshiaki , Ohta Hiromitsu , Yamaguchi Yasuhiro 
Published: July 2021

AbstractLung cancers with anaplastic lymphoma kinase (ALK) rearrangements are highly sensitive to treatment with ALK tyrosine kinase inhibitors (TKIs). Due to the very low rate of patients with squamous cell carcinoma enrolled in clinical trials, the efficacy of ALK inhibitors in patients with ALK‐rearranged squamous cell carcinoma in the lung remains unclear. Herein, we present the case of a 70‐year‐old female patient with squamous cell lung cancer harboring the echinoderm microtubule‐associated protein‐like 4 (EML4)‐ALK fusion gene. The patient was treated with the ALK‐TKI alectinib as first‐line regimen and achieved a dramatic response without severe adverse events, demonstrating alectinib as a therapeutic option for patients with ALK‐positive squamous cell carcinoma.
Conservative management of a cervical horizontal root fracture by long‐term stabilisation: A case report
Authors: Özler Cansu Özşin , Cehreli Zafer C. 
Published: July 2021

AbstractCervical root fractures are often more difficult to manage than fractures of the apical and middle third of the root, due to the weak chance of healing with dental hard tissue between fragments, and the likelihood of subsequent infection of the root canal system. This case report describes the management of a cervical horizontal root fracture by repositioning the coronal fragment of a maxillary central incisor, and long‐term splinting using a bonded lingual orthodontic retainer wire. Throughout the 7‐year stabilisation period with clinical and radiographic follow‐up, the tooth has remained asymptomatic with radiographic evidence of progressive pulp canal obliteration. In applicable cases, long‐term stabilisation of the fractured coronal fragment with a fixed orthodontic retainer may offer a minimally invasive solution to maintain pulp vitality, function and aesthetics until cessation of growth or until a more comprehensive, multidisciplinary approach is required.
Post robotic investment: Cost consequences and impact on length of stay for obese women with endometrial cancer
Authors: Korsholm Malene , Gyrd‐Hansen Dorte , Mogensen Ole , Möller Sören , Joergensen Siv L. , Jensen Pernille T. 
Published: July 2021

AbstractIntroductionThe aim of the study was to investigate whether robotic‐assisted surgery is associated with lower incremental resource use among obese patients relative to non‐obese patients after a Danish nationwide adoption of robotic‐assisted surgery in women with early‐stage endometrial cancer. This is a population‐based cohort study based on registers and clinical data.Material and methodsAll women who underwent surgery (robotic, laparoscopic and laparotomy) from 2008 to 2015 were included and divided according to body mass index (<30 and ≥30). Robotic‐assisted surgery was gradually introduced in Denmark (2008–2013). We compared resource use post‐surgery in obese vs non‐obese women who underwent surgery before and after a nationwide adoption of robotic‐assisted surgery. The key exposure variable was exposure to robotic‐assisted surgery. Clinical and sociodemographic data were linked with national register data to determine costs and bed days 12 months before and after surgery applying difference‐in‐difference analyses.ResultsIn total, 3934 women were included. The adoption of robotic‐assisted surgery did not demonstrate statistically significant implications for total costs among obese women (€3,417; 95% confidence interval [CI] −€854 to €7,688, p = 0.117). Further, for obese women, a statistically significant reduction in bed days related to the index hospitalization was demonstrated (−1.9 bed days; 95% CI −3.6 to −0.2, p = 0.025). However, for non‐obese women, the adoption of robotic‐assisted surgery was associated with statistically significant total costs increments of €9,333 (95% CI €3,729–€1,4936, p = 0.001) and no reduction in bed days related to the index hospitalization was observed (+0.9 bed days; 95% CI −0.6 to 2.3, p = 0.242).ConclusionsThe national investment in robotic‐assisted surgery for endometrial cancer seems to have more modest cost implications post‐surgery for obese women. This may be partly driven by a significant reduction in bed days related to the index hospitalization among obese women, as well as reductions in subsequent hospitalizations.
4 Cholula: The Mall of [Meso]america
Authors: McCafferty Geoffrey G. 
Published: July 2021

ABSTRACTEthnohistoric sources describe the market of Postclassic Cholula as featuring goods from throughout Mesoamerica. Furthermore, the merchant guilds centered in the city, followers of the god Yacatecuhtli/Quetzalcoatl, were elevated to princely status. Contact‐period sources also describe the political organization of the city, in which these merchant princes played a prominent role. The far‐flung influence of the religio‐commercial diaspora is represented through the distinctive symbolism of the Mixteca‐Puebla stylistic tradition, found throughout Postclassic Mesoamerica and as far south as Pacific Nicaragua. This paper uses the ethnohistorical evidence to construct a model of Cholula's urban economy and its international influence, with archaeological evidence to critically evaluate the sources.
6 Urban Commerce in the Jovel Valley of Highland Chiapas
Authors: Paris Elizabeth H. , López Bravo Roberto 
Published: July 2021

ABSTRACTThe Late Classic and Early Postclassic civic centers of Moxviquil and Cerro Ecatepec/CV‐38, located in the Jovel Valley of highland Chiapas, supported a number of institutions that provide evidence for a low level of commercialization. These include a possible periodic marketplace in the Main Plaza of Moxviquil, indirect evidence of merchant activity, and the use of widely circulating formal currencies, media of exchange, and imported luxury goods. However, many imported commodities were not equally consumed at all sites in the valley, and many widely‐circulating currency items were ultimately deposited in elite funerary contexts.[Maya, Chiapas, marketplace, currency, exchange]
Baseline extended zone retinal vascular calibres associate with sensory nerve abnormalities in adolescents with type 1 diabetes: A prospective longitudinal study
Authors: Velayutham Vallimayil , Benitez‐Aguirre Paul Z. , Liew Gerald , Wong Tien Y. , Jenkins Alicia J. , Craig Maria E. , Donaghue Kim C. 
Published: July 2021

AbstractObjectiveThe relationship between retinal vascular calibres (RVCs) and diabetic neuropathy is unclear. We investigated associations between RVCs and sensory nerve abnormality in adolescents with type 1 diabetes.Research design and methodsIn a prospective longitudinal study of 889 adolescents with type 1 diabetes with baseline mean (±SD) age 14.1 ± 1.5 years and HbA1c IFCC 69.4 ± 14.1 mmol/mol (8.6 ± 1.3%), RVCs were assessed from baseline retinal photographs: ‘central zone’ calibres, summarized as central retinal arteriolar (CRAE) and venular equivalents (CRVE) and ‘extended zone’ calibres: mean width of arterioles (MWa) and venules (MWv). Sensory nerve abnormality was defined as at least one abnormal sensory quantitative testing from two thermal and two vibration threshold tests measured at foot every 1–2 years. Associations between baseline RVC and sensory nerve function were examined using generalized estimating equations and cumulative risk by Cox regression analyses.ResultsDuring a median study follow‐up of 6.2 [IQR 3.7–10.4] years, sensory nerve abnormality was found in 27% of adolescents. Narrower extended zone calibre quartiles but not CRAE or CRVE quartiles were independently associated with sensory nerve abnormality: MWa (Q1 vs. Q2‐4: OR 1.35 (95% CI 1.02, 1.61) and MWv (Q1 vs. Q2‐4: 1.31 (1.03, 1.7)), after adjusting for HbA1c, duration and blood pressure. Similarly, in Cox regression, the narrowest quartiles were associated with sensory nerve abnormality: MWa hazard ratio (HR) 1.5 (1.3, 1.8) and MWv 1.6 (1.4, 1.9).ConclusionsNarrower extended zone retinal calibres were associated with sensory nerve abnormality in adolescents with type 1 diabetes and may present useful biomarkers to understand the pathophysiology of neuropathy.
A hybrid feature selection model based on butterfly optimization algorithm: COVID‐19 as a case study
Authors: EL‐Hasnony Ibrahim M. , Elhoseny Mohamed , Tarek Zahraa 
Published: July 2021

AbstractThe need to evolve a novel feature selection (FS) approach was motivated by the persistence necessary for a robust FS system, the time‐consuming exhaustive search in traditional methods, and the favourable swarming manner in various optimization techniques. Most of the datasets have a high dimension in many issues since all features are not crucial to the problem, which reduces the algorithm's accuracy and efficiency. This article presents a hybrid feature selection approach to solve the low precision and tardy convergence of the butterfly optimization algorithm (BOA). The proposed method is dependent on combining the algorithm of BOA and the particle swarm optimization (PSO) as a search methodology using a wrapper framework. BOA is started with a one‐dimensional cubic map in the proposed approach, and a non‐linear parameter control technique is also implemented. To boost the basic BOA for global optimization, PSO algorithm is mixed with the butterfly optimization algorithm (BOAPSO). A 25 dataset evaluates the proposed BOAPSO to determine its efficiency with three metrics: classification precision, the selected features, and the computational time. A COVID‐19 dataset has been used to evaluate the proposed approach. Compared to the previous approaches, the findings show the supremacy of BOAPSO for enhancing performance precision and minimizing the number of chosen features. Concerning the accuracy, the experimental outcomes demonstrate that the proposed model converges rapidly and performs better than with the PSO, BOA, and GWO with improvement percentages: 91.07%, 87.2%, 87.8%, 87.3%, respectively. Moreover, the proposed model's average selected features are 5.7 compared to the PSO, BOA, and GWO, with average features 22.5, 18.05, and 23.1, respectively.
Implementing Open Dialogue approaches: A scoping review
Authors: Buus Niels , Ong Ben , Einboden Rochelle , Lennon Elizabeth , Mikes‐Liu Kristof , Mayers Steven , McCloughen Andrea 
Published: July 2021

AbstractOpen Dialogue approaches fall broadly into the area of systemic psychotherapeutic practices. They encourage active participation of families and social networks, and emphasize genuine collaboration within highly integrated systems of health‐care service delivery. These approaches are currently being implemented in a growing number of services across the globe, and in this review, we summarize and discuss insights from papers concerned with the implementation of Open Dialogue. We used a scoping review method, which included systematic literature searches and summarizing data extraction as well as consultation with eight Open Dialogue implementation stakeholders who were invited to comment on preliminary review findings and a draft paper. We included 18 studies in the review and present their content under four thematic headings: 1. Training, 2. Family and network experiences, 3. Staff members’ experiences, and 4. Structural and organizational barriers and resistance to implementation. In general, the studies did not include rich descriptions of the implementation contexts, which made it difficult to draw conclusions across studies about effective implementation practices. The discussion draws on Jamous and Peloille’s (Professions and professionalisation, 1970, Cambridge University Press, 109‐152) concepts of “indeterminacy” and “technicality,” and we argue that the indeterminacy that dominates Open Dialogue is a challenge to implementation efforts that favor specific and standardized practices. We conclude by encouraging the development of implementation initiatives that theorize Open Dialogue practices with higher levels of technicality without corrupting the fundamental spirit of the approach.
Factors associated with psychological distress in family caregivers: Findings from nationwide data in Japan
Authors: Sun Yu , Iwagami Masao , Watanabe Taeko , Sakata Nobuo , Sugiyama Takehiro , Miyawaki Atsushi , Tamiya Nanako 
Published: July 2021

AimFamily caregivers can experience psychological distress, resulting in physical and mental health problems, and discontinuation of caregiving. This study's objective was to examine factors associated with caregiver psychological distress.MethodsWe analyzed data from the Comprehensive Survey of Living Conditions in 2007, 2010, 2013 and 2016, which included 12 504 pairs of caregivers and care recipients sharing a household in Japan. Kessler's Psychological Distress Scale (K6) was used to measure caregiver psychological distress. Multivariable logistic regression analyses identified factors associated with caregiver psychological distress (K6 score ≥5).ResultsCaregivers' median K6 score was 3 (interquartile range 0–7), and 38.6% had a K6 score ≥5. K6 scores ≥5 were positively associated with female sex (adjusted odds ratio 1.35, 95% CI 1.21–1.51), poor caregiver health status (compared with “very good,” 9.48, 95% CI 7.91–11.37 for “not very good/poor”), longer care time (compared with “help only when needed,” 1.40, 95% CI 1.25–1.58 for “almost all day”) and dementia (1.16, 95% CI 1.05–1.28), lower respiratory tract disease (1.25, 95% CI 1.06–1.49) and diabetes (1.16, 95% CI 1.00–1.33) in care recipients. K6 scores ≥5 were negatively associated with older caregiver age (compared with 20–54 years, 0.65, 95%CI 0.58–0.74 for 55–64 years, 0.54, 95%CI 0.46–0.63 for 65–74 years and 0.50, 95% CI 0.40–0.62 for ≥75 years), employment (0.88, 95% CI 0.80–0.97) and being a care recipient's child‐in‐law (compared with spouse 0.75, 95% CI 0.61–0.92).ConclusionsThe findings identified several factors associated with caregiver psychological distress, showing that particular attention might need to be paid to caregivers with these risk factors. Geriatr Gerontol Int 2021; 21: 855–864.
COVID‐19 in hospitalized HIV‐positive and HIV‐negative patients: A matched study
Authors: Díez Cristina , Del Romero‐Raposo Jorge , Mican Rafael , López Juan C. , Blanco José R. , Calzado Sonia , Samperiz Gloria , Portilla Joaquín , García‐Fraile Lucio J. , Gutiérrez Félix , Gómez‐Sirvent Juan L. , Suárez‐García Inés , Amador Concha , Novella María , Arribas Jose R. , Moreno Santiago , González‐García Juan , Jarrín Inmaculada , Berenguer Juan ,   for CoRIS
Published: July 2021

AbstractObjectivesWe compared the characteristics and clinical outcomes of hospitalized individuals with COVID‐19 with [people with HIV (PWH)] and without (non‐PWH) HIV co‐infection in Spain during the first wave of the pandemic.MethodsThis was a retrospective matched cohort study. People with HIV were identified by reviewing clinical records and laboratory registries of 10 922 patients in active‐follow‐up within the Spanish HIV Research Network (CoRIS) up to 30 June 2020. Each hospitalized PWH was matched with five non‐PWH of the same age and sex randomly selected from COVID‐19@Spain, a multicentre cohort of 4035 patients hospitalized with confirmed COVID‐19. The main outcome was all‐cause in‐hospital mortality.ResultsForty‐five PWH with PCR‐confirmed COVID‐19 were identified in CoRIS, 21 of whom were hospitalized. A total of 105 age/sex‐matched controls were selected from the COVID‐19@Spain cohort. The median age in both groups was 53 (Q1–Q3, 46–56) years, and 90.5% were men. In PWH, 19.1% were injecting drug users, 95.2% were on antiretroviral therapy, 94.4% had HIV‐RNA < 50 copies/mL, and the median (Q1–Q3) CD4 count was 595 (349–798) cells/μL. No statistically significant differences were found between PWH and non‐PWH in number of comorbidities, presenting signs and symptoms, laboratory parameters, radiology findings and severity scores on admission. Corticosteroids were administered to 33.3% and 27.4% of PWH and non‐PWH, respectively (P = 0.580). Deaths during admission were documented in two (9.5%) PWH and 12 (11.4%) non‐PWH (P = 0.800).ConclusionsOur findings suggest that well‐controlled HIV infection does not modify the clinical presentation or worsen clinical outcomes of COVID‐19 hospitalization.