bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sella Turcica Bridging and its Association with Dental Anomalies
Authors: Siddalingappa Divya , Urala Arun S. , Pentapati Kalyana C. , Vineetha Ravindranath , Prasad G. Lakshmi 
Published: September 2021

Aim:
This study aimed to study the overall incidence of DA and its association with Sella Turcica bridging (STB).

Background:
Dental anomalies (DA) are associated with morphological changes in the Sella Turcica (ST).

Materials and Methods:
We retrieved the pretreatment patient records from March 2018 - March 2020 from the archives of the Orthodontics Department (n=806). We excluded the records with missing radiographs, concomitant cleft lip/ palate, history of surgical repair of cleft lip/ palate or any other craniofacial anomaly, history of trauma, and prior orthodontic treatment. A total of 676 patient records were included for initial screening, out of which 103 patients had DA (study group). A similar number of records (n=103) without any DA were randomly selected to constitute a control group. Determination of the extent of STB was done by calibrated and trained examiner. Age and sex were also recorded.

Results:
The incidence of DA was 15.24%. The most common anomalies recorded were impacted canines (6.8%) and hyperdontia (3.7%), followed by agenesis (2.1%) and others. Type III bridging in patients with DA was 22.3%, while being 9.7% in the control group. Type II bridging was observed in 36.8% of patients with DA as compared to 29.1% in the control group. The presence of partial and complete STB in patients with dental anomalies was significantly higher than in the control group (P=0.006). The study group showed significant association with STB (OR: 2.33; P=0.003; 95%CI: 1.33-4.11) after adjusting for sex.

Conclusion:
The results of our study revealed a significant association between STB and DA.
The senior year students’ persistence profile of UMTAS (University of Muhammadiyah Tasikmalaya)
Authors: Luanda Aditia , Isti’adah Feida Noor Laila , Nugraha Agung 
Published: September 2021

This study aims to determine the profile of senior year students at the end of class 2015 that have been studied for 4 years or undergraduate students (S1). This descriptive study was conducted to 10 study programs (S1) at the University of Muhammadiyah Tasikmalaya with a sample number of 142 students. Measuring instrument employed in the form of a questionnaire multiple choice that refers to the grand theory of Pury (Lopez, 2009), which was designed by the researcher in 2019. The results revealed that the persistence of 2015 students was in high category with a percentage of 77.33%. The number of final-level students in the high category of 85% or 121 students, in addition there were 14% or 20 students who belonged to the medium category and 1% or 1 student was in the low category. This indicates that in general, the senior students at the Universitas Muhammadiyah Tasikmalaya have demonstrated maximum persistence in each dimension, including having high desire and awareness to pursue their goals, doing hard effort sustainably, instilling persistent character in resolving the problems, as well as the students can survive and move forward despite the challenges and difficulties in achieving their objectives. Keywords: persistence, student of university
Achieving ideal career: improving student’s career self efficacy through career counseling sessions based on H.B Gelatt's decision theory
Authors: Chudari Ima Ni’mah , Mashudi Esya Anesty , Fatihaturosyidah Fatihaturosyidah 
Published: September 2021

After successfully compiling a good career plan related to their professional work in the future, students are expected to realize these career plans successfully. For this reason, students need to be equipped with other abilities in the form of self-efficacy or the ability to believe that the efforts made will produce results and goals that are expected to be achieved. Therefore, through appropriate career counseling intervention, the self-efficacy of students in achieving an ideal career is expected to increase. This study aims to examine effectiveness of career counseling based on H.B Gelatt's decision theory to improve student self-efficacy in achieving an ideal career. This study uses quasi-experimental methods. The research subjects were third years students in UPI Serang. The research instrument used was a student self-efficacy scale and a daily reflective journal. Data analysis techniques used statistical testing in the form of percentages, central symptom measures, and two-tier test (t-test). The results showed that students' self-efficacy related to achieving an ideal career in general was in the medium category with a percentage of 50.72%. The counseling intervention program is based on the career decision making steps of Gelatt. Paired t-test results of pre-test and post-test of the experimental group showed that t arithmetic = 10.221> (greater) than t table = 2.401, testing was carried out at a = 0.05 and df = 39, meaning H1 was accepted and H0 was rejected. Thus, there is a significant difference between self-efficacy related to achieving the ideal career of students who are members of the experimental group before and after receiving treatment. Decision-making skills in particular are very influential on improving the level dimension in student self-efficacy related to achieving an ideal career. Keywords: career counseling, career counseling in college, career self-efficacy, Gelatt decision-making theory
Risks for obesity development, features of food behavior and bio-impedansemetric parameters in adolescents
Authors: Kocherha Z.R. , Nedostup I.S. , Pavlykivska B.M. , Tereshkun N.M. , Kazimyrchuk I.V. 
Published: September 2021

Background. The problem of obesity in adolescents has gained its medical and social relevance since the incidence of the disease is steadily increasing. The purpose of the study is to improve the effectiveness of early diagnosis and prevention of obesity in adolescents. Materials and methods. To study the risk factors for obesity, a comparative assessment of lifestyle among adolescents aged 15–17 years with obesity, overweight and physiological body weight was conducted. In adolescents of the same age with comorbid obesity (basic group), overweight and physiological body weight (two comparison groups), the types of food behavior were determined using the Dutch eating behavior questionnaire (DEBQ). Bioelectrical indicators of bio-impedancemetric analysis were studied on a Tanita apparatus (Japan). The probability of differences in mean values was determined using Student’s t-test. Results. It was found that the frequency of imbalance of the food pyramid, movement disorders, sleep and rest, nervous tension, burdened heredity increased significantly among obese adolescents. Obesity was found to dominate by external type of eating behavior (57.2 %); at the excess weight — restrictive type (60 %); at physiological body weight — emotional type (40 %). Bio-impedancemetry showed that the reliable bioelectrical parameters of obesity were total fat (35.5 ± 4.5 % and 29 ± 2 % vs. 17.5 ± 2.5 %); visceral fat (17 ± 2 % and 12 ± 3 % vs. 8.5 ± 1.5 %); and metabolic age (33 ± 8 and 21.5 ± 1.5 years versus 16 ± 1 years). Conclusions. Risk factors for obesity include the imbalance of the food pyramid, movement disorders, sleep and rest, nervous tension, bad habits, burdened heredity. The predominance of external type of eating behavior in obesity, restrictive — in overweight and emotional type in adolescents with physiological body weight should be taken into account when prescribing personalized lifestyle adjustments. The most informative bioelectrical parameters of bio-impedancemetry were total fat, visceral fat, and metabolic age. Bio-impedancemetry as a non-invasive predictive method of diagnosing obesity can be recommended for widespread implementation in pediatric practice.
Postoperative agitation syndrome in young children with perinatal damage to the central nervous system
Authors: Snisar V.I. , Pavlysh O.S. 
Published: September 2021

One of the complications of the postoperative period in children is postanesthetic agitation, a significant emotional and uncontrollable worry, clouding of consciousness, feeling of anxiety and fear, inappropriate behavior, irritability, inconsolable crying, aggressive and negative attitude towards parents and medical staff. Postoperative agitation is very important for clinicians and hospitals, it has a risk of harming a patient, staying longer in the ward after anesthesia, and increasing the period of postoperative recovery. The frequency of postoperative agitation depends on age group. Most often agitation occurs in young children. There is evidence that agitation can also be due to the immature nervous system and a consequence of pathological conditions of the central nervous system (asthenoneurotic syndrome, encephalopathy, hyperactivity syndrome, perinatal posthypoxic and organic brain lesions, history of prematurity, epilepsy, psychophysical and speech delay, etc.). That is why the goal of our research was to study the patterns of clinical manifestations of postoperative agitation syndrome in children with prenatal damage to the central nervous system. The work was performed based on the analysis of the postoperative period in 109 young children: 59 patients with acquired hydrocephalus, who underwent ventriculoperitoneal shunting, and 50 children without neurological disorders in whom reconstructive surgeries were carried out. Depending on the type anesthetic management, each group was divided into two subgroups: children, who received inhalation anesthesia with sevoflurane, and those, who received total intravenous anesthesia using propofol. In the postoperative period, the behavior of children was assessed on a Pediatric Anesthesia Emergence Delirium scale 30 minutes after anesthesia was completed. Criterion for the development of agitation was the presence of excitement in a child with a score of ≥ 10 points. Study showed that young children with perinatal damage to the central nervous system and children whose anesthetic provision is carried out using sevoflurane are the most vulnerable to the development of agitation syndrome. Agitation in such children is more pronounced and longer. These cases require prediction, detection and active surveillance.
Blockchain Technology, Inter-Organizational Relationships, and Management Accounting: A Synthesis and a Research Agenda
Authors: Kostić Nikola , Sedej Tomaz 
Published: September 2021

SYNOPSIS
Blockchain technology is increasingly emerging as an important organizational phenomenon, especially for collaboration across firm boundaries. Over the past three decades, accounting scholars have shown significant interest in management accounting and control mechanisms that are used by actors to sustain inter-organizational relationships. We outline fundamental technical features and limitations of permissioned blockchain technology and analytically propose blockchain as an empirical concept with implications for management accounting practices that underpin inter-organizational collaboration, trust, control, and information exchange. Particular focus of the analysis is on the interplay between the technical capabilities of blockchain technology and inter-organizational management control procedures. Based on this analysis, we develop a series of propositions that theorize how these procedures affect the way in which blockchain is enacted in IORs, and how they are affected by blockchain in turn. The paper concludes with a research agenda for accounting scholars and offers directions for further research.
Stakeholder Engagement and Effective Standard Setting
Authors: Convery Amanda M. , Kaufman Matt , Warfield Terry D. 
Published: September 2021

SYNOPSIS
Successful standard-setting outcomes require some level of acceptance by diverse stakeholder groups. This study examines the evolution of FASB due process institutions since Enron, which have the potential to engender stakeholder acceptance. The prior literature on accounting standard-setting outcomes often focuses on the effects of individuals, organizations, or established due process institutions. Our study highlights the critical role played by recent due process institutions such as enhanced advisory groups, transition resource groups, field tests, and post-implementation reviews in contemporary standard-setting activity. Advisory groups, in particular, shift the balance of power within standard-setting to give a stronger voice to specific stakeholders (e.g., investors, not-for-profits, and private companies) and sometimes provide a recruiting network for future FASB members. We highlight the growing importance of these due process institutions for effective standard-setting outcomes, as well as implications for future academic research.
Data Availability: Data are available from the public sources cited in the text.
JEL Classifications: M41; M48.
Application of High Hydrostatic Pressure (HHP) to Improve Cryopreservation of Young Bull Semen
Authors: Szczęśniak-Fabiańczyk Barbara , Gogol Piotr , Gajda Lechosław , Smorąg Zdzisław 
Published: September 2021

Abstract
The objective of the study was to determine the effect of high hydrostatic pressure (HHP) on quality of cryopreserved semen of young bulls. Semen for this study was collected from 8 bulls aged between 13 and 18 months at monthly intervals, from June to September. After collection, semen was diluted in a commercial Bioxcell® extender (one part at 1:1 and a second part to give a sperm concentration of 20 million/0.2 mL), filled into straws and treated with HHP at 30 MPa for 90 min. After HHP treatment, pre-diluted semen (1:1) was diluted to a sperm concentration 20 million/0.2 mL and filled into straws. In addition, part of the semen diluted to a concentration of 20 million/0.2 mL was not treated with HHP (control). All of it was held at +4°C and frozen in a freezer after 2.5-h equilibration. Semen was thawed in a water bath at 38°C and subjected to estimation of the percentage of motile sperm both subjectively and using a computer-assisted semen analyzer and cytometric assessment of sperm cell membrane integrity. Subjective motility and fast progressive motility were significantly higher with pre-diluted (1:1) and HHP treated semen compared to control (P<0.05). No significant differences were observed in percentage of membraneintact spermatozoa between control and experimental groups. Additionally, the influence of HHP on the sperm of individual bulls was assessed. In bull number 2, the HHP treatment after semen pre-dilution significantly improved progressive motility from 54.1 to 63.4 percent (P<0.05). In bull number 4, the HHP treatment after semen pre-dilution significantly improved subjective motility, rapid motility and progressive motility by 12.5, 16.8 and 16.3 percent, respectively (P<0.05). No effect was seen for 6 bulls. It is concluded that for some bulls, the application of HHP before semen freezing may improve the cryopreservation outcome. However, this requires further research in this area, also to determine the fertilizing capacity of bull semen exposed to high hydrostatic pressure.
An Introduction to the Special Issue on Numerical Techniques Meet with OR - Part II
Authors: Gürbüz Burcu , Weber Gerhard-Wilhelm 
Published: September 2021

Abstract
The special issue: “Numerical Techniques Meet with OR” of the Foundations of Computing and Decision Sciences consists of two parts which are of the main theme of numerical techniques and their applications in multi-disciplinary areas. The first part of this special issue was already collected in the FCDS Vol. 46, issue 1. In this second part of our special issue editorial, a description of the special issue presents numerical methods which can be used as alternative techniques for Scientific Computing and led Operational Research applications in many fields for further investigation.
Some New Characterizations of The Harmonic and Harmonic 1-Type Curves in Euclidean 3-Space
Authors: Samanci Hatice Kuşak , Ayaz Sedat , Kocayiğit Huseyin 
Published: September 2021

Abstract
A Laplace operator and harmonic curve have very important uses in various engineering science such as quantum mechanics, wave propagation, diffusion equation for heat, and fluid flow. Additionally, the differential equation characterizations of the harmonic curves play an important role in estimating the geometric properties of these curves. Hence, this paper proposes to compute some new differential equation characterizations of the harmonic curves in Euclidean 3-space by using an alternative frame named the N-Bishop frame. Firstly, we investigated some new differential equation characterizations of the space curves due to the N-Bishop frame. Secondly, we firstly introduced some new space curves which have the harmonic and harmonic 1-type vectors due to alternative frame N-Bishop frame. Finally, we compute new differential equation characterizations using the N-Bishop Darboux and normal Darboux vectors. Thus, using these differential equation characterizations we have proved in which conditions the curve indicates a helix.
Traditional Chinese medicine in the treatment of high incidence diseases in cold areas: the thrombotic diseases
Authors: Tang Xueqing , Liu Xin , Mikaye Monayo Seth , Zhao Hongrui , Zhang Yong 
Published: September 2021

Abstract
Thrombotic diseases are the leading causes of death worldwide, especially in cold climates. Traditional Chinese medicine (TCM)-based therapies have gained increasing popularity worldwide, but also raised some concerns about its efficacy, safety profile and exact mechanisms. TCM has been traditionally used in the management of thrombosis and convincingly proven effective in modifying thrombosis progression, particularly the platelet function, coagulation system and fibrinolytic system. This review article focuses on TCM regulation of thrombosis with brief discussion on the fundamental aspects and relevant background information for better understanding of the subject. In addition to its antithrombotic effects, we will dive insight into the cellular and molecular mechanisms of TCM as pharmacological regulators of platelet aggregation, coagulation, and fibrinolysis. With increasing awareness and understanding of the benefits and potentials of TCM, TCM products will in no doubt gain its broader applications in the treatment of thrombosis and associated disorders, which in turn will deepen our understanding of its pharmacological and molecular mechanisms. Finally, current review provides a perspective view on the future directions to TCM research on thrombosis.
Tridepsides from the endophytic fungus colletotrichum gloeosporioides associated with a toxic medicinal plant tylophora ovata
Authors: Sun Sen-Feng , Zhu Shao , Cao Hai-Yan , Liu Yun-Bao , Yu Shi-Shan 
Published: September 2021

Abstract

Introduction
Bioactive secondary metabolites from the microbes living in frigid, toxic or other extreme environments are emerging as a new medicinal resource. Here, we report the discovery of new antidiabetic and anti-inflammatory compounds with novel structures from endophytic fungi hosted toxic medicinal plant.

Methods
The endophytic fungus isolated from toxic plants was fermented and extracted. The obtained extracts were purified with preparative HPLC to yield pure compounds. The purified compounds were examined by PTP1b inhibition and NO inhibition assays to evaluate their bioactivities.

Results
One new tridepsides (Compound 1), one new benzeneacetic acid derivative (Compound 3) and five known compounds (Compounds 2 and 4-7) were isolated from the ethyl acetate extract of Colletotrichum gloeosporioides, an endophytic fungus obtained from a toxic medicinal plant Tylophora ovata. Their structures were determined by spectroscopic data (1D and 2D NMR, HRESIMS) analyses. Compound 2 showed significant inhibitory activity against PTP1b with an IC50 value of 0.84 μM. Compounds 2 and 3 exhibited moderate inhibitory activities against the NO (nitric oxide) release in LPS-induced RAW 264.7 cells at 10 μM with percent inhibition of 39% and 33%, respectively.

Conclusion
The Compound 2 has potent PTP1b inhibitory effect indicating its antidiabetic potential and thus might be considered a lead compound for antidiabetic drug development.
Ablation of apoptosis-stimulating of p53 protein 1 protects mice from acute hepatic injury and dysfunction via NF-κB pathway in CCl4-induced hepatotoxicity
Authors: Daba Tolessa Muleta , Huang Xiang , Yagudin Timur , Yang Ying , Wang Jiangang , Fu Xiaoyu , Zhao Yue , Gao Haiyu , Zhou Yang , Pan Zhenwei , Zhong Xiangyu 
Published: September 2021

Abstract
Acute liver injury (ALI) is characterized by apoptosis, inflammation, and oxidative stress, and pathogenic mechanism of ALI is poorly understood. Apoptosis-stimulating of p53 protein 1 (ASPP1) is involved in environmental responses, tumor growth, and NF-KB activity, which is of critical importance to ALI. However, the role of ASPP1 in ALI remains largely unexplored. The current study aimed to determine the role of ASPP1 in ALI induced by CCl4 and the underlying mechanism. ASPP1 expression was detected in wild type (WT) mice with ALI induced by CCl4. The function of ASPP1 in ALI induced by CCl4 was investigated using conventional knockout ASPP1 mice. ASPP1 expression significantly increased in ALI mice at 24 hours after CCl4 injection. Deletion of ASSP1 ameliorated apoptosis, inflammation, and necrosis in ALI relative to WT mice. In addition, deficiency of ASPP1 improved liver flood flow as well as ALT and AST levels. The levels of phosphorylated p65 and phosphorylated IκBα were lower in ASPP1-/- mice than in WT mice with ALI. These results implicate that deletion of ASPP1 may act via inhibition of the NF-κB pathway and protect mice from ALI, which may be a new potential therapeutic target for the treatment of ALI.
The Safety Profile of the Anesthetic Effect of Alfaxalone and its Interaction with Xylazine and Ketamine in Chick’s Model (Gallus Gallus Domesticus)
Authors: Alatrushi Amjed Najem , Naser Ahmed Salah 
Published: September 2021

Abstract
The objective of our research was to estimate the therapeutic index and assess the interaction of alfaxalone (IP) with ketamine or xylazine (IM) in chicks by using isobolographic analysis. The up-and-down technique was involved to calculate the median effective anesthetic dosages (ED50) of alfaxalone, xylazine, and ketamine given separately or at the same time in young chicks. Then the up-and-down technique was involved to estimate the median lethal dosage (LD50) of alfaxalone (IP) to determine the safety profile. The ED50 of all anesthetics was evaluated isobolographically to assess the type of interaction between alfaxalone and xylazine or alfaxalone and ketamine. The alfaxalone ED50 was 32.88 mg/kg (IP), whereas the LD50 was 102.40 mg/kg (IP). The ED50 values for alfaxalone, ketamine, and xylazine were 32.88, 12.24, and 2.45 mg/kg, respectively. The ED50 values of alfaxalone with ketamine or xylazine (25:25 ED50 values) were: 7.39+2.35, and 8.61+0.63 mg/kg, respectively. ED50 values were decreased when the combinations of alfaxalone/ketamine or alfaxalone/xylazine were administered by 22-21% and 26-25%, respectively. The anesthesia of chicks with alfaxalone is safe, produces a surgical stage of anesthesia, and can be used for minor surgical procedures. The use of alfaxalone with ketamine or xylazine has been shown to have a synergistic effect and these findings may be of clinical relevance in poultry or may be extended to mammals following further clinical trials.