bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Committee Evolutionary Neural Network for the Prediction of Combined Sewer Overflows
Authors: Rosin T. R. , Romano M. , Keedwell E. , Kapelan Z. 
Published: February 2021

AbstractCombined Sewer Overflows (CSOs) are a major source of pollution and urban flooding, spilling untreated wastewater directly into water bodies and the surrounding environment. If overflows can be predicted sufficiently in advance, then techniques are available for mitigation. This paper presents a novel bi-model committee evolutionary artificial neural network (CEANN) designed to forecast water level in a CSO chamber from 15 min to 6 h ahead using inputs of past/current CSO level data, radar rainfall data and forecast forecasted rainfall data. The model is composed of two evolutionary artificial neural network (EANN) models. The two models are trained and optimised for wet and dry weather conditions respectively and their results combined into a single response using a non-linear weighted averaging approach. An evolutionary strategy algorithm is employed to automatically select the optimal artificial neural network (ANN) structure and parameter set, allowing the network to be tailored specifically for different CSO locations and forecast horizons without significant human input. The CEANN model was tested and evaluated on real level data from 4 CSOs located in Northern England and the results compared to three other ANN models. The results demonstrate that the CEANN model is superior in terms of accuracy for almost all forecast horizons considered. It is able to accurately forecast the dry weather and wet weather level, predicting the timing and magnitude of upcoming spill events, thus providing information that is of clear use to a wastewater utility.
Lactobacillus plantarum strain HT-W104-B1: potential bacterium isolated from Malaysian fermented foods for control of the dermatophyte Trichophyton rubrum
Authors: Danial Azlina Mohd , Medina Angel , Magan Naresh 
Published: February 2021

AbstractThe objective was to screen and evaluate the anti-fungal activity of lactic acid bacteria (LABs) isolated from Malaysian fermented foods against twoTrichophytonspecies. A total of 66 LAB strains were screened using dual culture assays. This showed that four LAB strains were very effective in inhibiting growth ofT. rubrumbut notT. interdigitale.More detailed studies withLactobacillus plantarumstrain HT-W104-B1 showed that the supernatant was mainly responsible for inhibiting the growth ofT. rubrum. The minimum inhibitory concentration (MIC), inhibitory concentration, the 50% growth inhibition (IC50) and minimum fungicide concentration (MFC) were 20 mg/mL, 14 mg/mL and 30 mg/mL, respectively. A total of six metabolites were found in the supernatant, with the two major metabolites being L-lactic acid (19.1 mg/g cell dry weight (CDW)) and acetic acid (2.2 mg/g CDW). A comparative study on keratin agar media showed that the natural mixture in the supernatants predominantly contained L-lactic and acetic acid, and this significantly controlled the growth ofT. rubrum. The pure two individual compounds were less effective. Potential exists for application of the natural mixture of compounds for the treatment of skin infection byT. rubrum.
An evaluation of the occurrence and trends in 137Cs and 40K radioactivity in King Bolete Boletus edulis mushrooms in Poland during 1995–2019
Authors: Falandysz Jerzy , Zalewska Tamara , Saniewski Michał , Fernandes Alwyn R. 
Published: February 2021

AbstractB. edulis, collected from 33 forested or woodland sites across Poland over 25 years since 1995, were analysed for radiocaesium. The results (137Cs activity range: 25 to 10,000 Bq kg-1 dry weight) provide a good indication of artificial radioactivity in this food material. The relatively higher levels detected in the earlier years, mostly in easterly location, is consistent with depositions from the projected Chernobyl incident (1986) fallout plumes. Nevertheless, the 137Cs concentrations during 1995–2010 were, on average, higher than those reported by other studies for Polish B. edulis over the period 1986–1994. The data concurs with the general hypothesis and observations that deposited 137Cs permeates slowly over time to deeper soil horizons which host the mycelial networks. This delay in availability shows that (apart from hotspots) higher contamination of fruiting bodies occurred around 10 to 20 years after the incident. Local consumers and recreational mushroomers were undoubtedly exposed, although reported 137Cs concentrations suggest that serious breaches of regulated levels were uncommon.
Appropriate use criteria for cardiovascular magnetic resonance imaging (CMR): SIC—SIRM position paper part 1 (ischemic and congenital heart diseases, cardio-oncology, cardiac masses and heart transplant)
Authors: Pontone Gianluca , Di Cesare Ernesto , Castelletti Silvia , De Cobelli Francesco , De Lazzari Manuel , Esposito Antonio , Focardi Marta , Di Renzi Paolo , Indolfi Ciro , Lanzillo Chiara , Lovato Luigi , Maestrini Viviana , Mercuro Giuseppe , Natale Luigi , Mantini Cesare , Polizzi Aldo , Rabbat Mark , Secchi Francesco , Secinaro Aurelio , Aquaro Giovanni Donato , Barison Andrea , Francone Marco 
Published: February 2021

AbstractCardiac magnetic resonance (CMR) has emerged as new mainstream technique for the evaluation of patients with cardiac diseases, providing unique information to support clinical decision-making. This document has been developed by a joined group of experts of the Italian Society of Cardiology and Italian society of Radiology and aims to produce an updated consensus statement about the current state of technology and clinical applications of CMR. The writing committee consisted of members and experts of both societies who worked jointly to develop a more integrated approach in the field of cardiac radiology. Part 1 of the document will cover ischemic heart disease, congenital heart disease, cardio-oncology, cardiac masses and heart transplant.
A Preliminary Trial of the Introduction of Computerized Decision Support to Assist Resuscitation of the Severely Injured in a Level 1 Trauma Centre in India
Authors: Fitzgerald Mark C. , Gupta Amit , Bhoi Sanjeev Kumar , Kim Yesul , Sharma Ankita , Jhakal Ashish , Mathew Joseph , Misra Mahesh Chandra 
Published: February 2021

AbstractInjury from motor vehicle accidents remains a leading cause of death in India with increasing number of fatalities. Timely delivery of lifesaving interventions is critical for survival and in restoring physical functioning. As a part of the Australia India Trauma Systems Collaboration, the Trauma Reception and Resuscitation (TRR©)-computerized decision support system was implemented in a Level 1 Trauma Centre in India in order to determine whether this system would reduce the time in performing lifesaving interventions and improve vital sign data capture and documentation. This prospective cohort study at the Jai Prakash Narayan Apex Center, All India Institute of Medical Science, New Delhi, recruited a total of 106 participants into two groups: TRR© (76) and controls (30). During the first 30 min of resuscitation, the TRR© group recorded greater sets of vital signs in compared to the controls for medical records. More importantly, the real-time documentation of the vital signs for the TRR© group ensured accuracy for medical records. For lifesaving interventions, oxygen was administered in the TRR© group only if SpO2 < 93%, whereas oxygen was administered as standard of care in the controls. There was no statistical difference in the mean times to endotracheal intubation, intercostal catheter insertion or performance of emergency chest x-ray between the control and TRR© groups. Importantly however, these 3 comparable interventions were performed consistently within a smaller timeframe for patients receiving care with TRR© decision prompts. There was a greater variability in the time taken to perform lifesaving interventions in the control group in comparison to the clinicians assisted with computerized decision prompts. This preliminary study was not powered to measure difference in mortality and patient recruitment was limited to 8 am–5 pm when trained staff could attend to operating the TRR© system.
What You Say or How You Say It? Depression Detection Through Joint Modeling of Linguistic and Acoustic Aspects of Speech
Authors: Aloshban Nujud , Esposito Anna , Vinciarelli Alessandro 
Published: February 2021

AbstractDepression is one of the most common mental health issues. (It affects more than 4% of the world’s population, according to recent estimates.) This article shows that the joint analysis of linguistic and acoustic aspects of speech allows one to discriminate between depressed and nondepressed speakers with an accuracy above 80%. The approach used in the work is based on networks designed for sequence modeling (bidirectional Long-Short Term Memory networks) and multimodal analysis methodologies (late fusion, joint representation and gated multimodal units). The experiments were performed over a corpus of 59 interviews (roughly 4 hours of material) involving 29 individuals diagnosed with depression and 30 control participants. In addition to an accuracy of 80%, the results show that multimodal approaches perform better than unimodal ones owing to people’s tendency to manifest their condition through one modality only, a source of diversity across unimodal approaches. In addition, the experiments show that it is possible to measure the “confidence” of the approach and automatically identify a subset of the test data in which the performance is above a predefined threshold. It is possible to effectively detect depression by using unobtrusive and inexpensive technologies based on the automatic analysis of speech and language.
Recycling of Waste MDF by Steam Refining: Evaluation of Fiber and Paper Strength Properties
Authors: Hagel Sebastian , Joy Jesan , Cicala Gianluca , Saake Bodo 
Published: February 2021

AbstractCurrently, most of the collected waste medium-density fiberboards (MDF) is incinerated or landfilled, as economically viable recycling methods are yet to be developed. By steam refining waste medium-density fiberboards (MDF), it is possible to hydrolyze the incorporated resins and isolate a high yield fiber fraction. Further refining of the steam treated fibers might enable the fibers to be utilized in applications such as paper packaging, facilitating a cascading use of the waste material stream. To this end, intimate knowledge of the material is needed. In this study, the steam refined fibers of two waste MDF samples containing differing amounts of softwood and hardwood underwent refining and beating. The resulting fibers were characterized regarding their morphology and paper test sheets were produced to evaluate their strength (compression-, tensile- and tear-strength). Distinct differences in response to refining between the MDF samples were apparent. For the sample with the higher hardwood share an increase in strength properties with increasing steam treatment severities could be observed and it was possible to produce test sheets with comparable compression strength to recycled pulp for industrial corrugated paperboard. For the sample with a higher share of softwood, the steam treatment severity did not show any influence on fiber morphology or paper properties, and the resulting paper strength was low in comparison to the other steam refined waste MDF sample.Graphic Abstract
On the Koebe Quarter Theorem for certain polynomials
Authors: Ignaciuk Szymon , Parol Maciej 
Published: February 2021

AbstractWe study problems similar to the Koebe Quarter Theorem for close-to-convex polynomials with all zeros of derivative in $${\mathbb {T}}:=\{z\in {\mathbb {C}}:|z|=1\}$$

T
:
=
{
z
∈
C
:
|
z
|
=
1
}

. We found minimal disc containing all images of $${\mathbb {D}}:=\{z\in {\mathbb {C}}: |z|<1\}$$

D
:
=
{
z
∈
C
:
|
z
|
<
1
}

and maximal disc contained in all images of $${\mathbb {D}}$$
D
through polynomials of degree 3 and 4. Moreover we determine the extremal functions for both problems.
Growth and Differentiation of Circulating Stem Cells After Extensive Ex Vivo Expansion
Authors: Barbon Silvia , Rajendran Senthilkumar , Bertalot Thomas , Piccione Monica , Gasparella Marco , Parnigotto Pier Paolo , Di Liddo Rosa , Conconi Maria Teresa 
Published: February 2021

Abstract
Background:
Stem cell therapy is gaining momentum as an effective treatment strategy for degenerative diseases. Adult stem cells isolated from various sources (i.e., cord blood, bone marrow, adipose tissue) are being considered as a realistic option due to their well-documented therapeutic potentials. Our previous studies standardized a method to isolate circulating multipotent cells (CMCs) that are able to sustain long term in vitro culture and differentiate towards mesodermal lineages.

Methods:
In this work, long-term cultures of CMCs were stimulated to study in vitro neuronal and myogenic differentiation. After induction, cells were analysed at different time points. Morphological studies were performed by scanning electron microscopy and specific neuronal and myogenic marker expression were evaluated using RT-PCR, flow cytometry and western blot. For myogenic plasticity study, CMCs were transplanted into in vivo model of chemically-induced muscle damage.

Results:
After neurogenic induction, CMCs showed characteristic dendrite-like morphology and expressed specific neuronal markers both at mRNA and protein level. The calcium flux activity of CMCs under stimulation with potassium chloride and the secretion of noradrenalin confirmed their ability to acquire a functional phenotype. In parallel, the myogenic potential of CMCs was confirmed by their ability to form syncytium-like structures in vitro and express myogenic markers both at early and late phases of differentiation. Interestingly, in a rat model of bupivacaine-induced muscle damage, CMCs integrated within the host tissue taking part in tissue repair.

Conclusion:
Overall, collected data demonstrated long-term cultured CMCs retain proliferative and differentiative potentials suggesting to be a good candidate for cell therapy.
Perioperative Management of Severe Acquired Coagulopathy in Patients with Left Ventricular Assist Device—a Literature Review and Expert Recommendations
Authors: Koster Andreas , Hulde Nikolai , von Dossow Vera , Erdoes Gabor 
Published: February 2021

Abstract
Purpose of This Review
The implantation of a left ventricular assist device (LVAD) is associated with high hemorrhage-related re-exploration rates. Improved management of coagulopathy may improve patient outcome. The optimal management of acquired coagulopathy in LVAD patients needing urgent non-cardiac surgery needs to be defined. We aim to review risk factors for perioperative bleeding and diagnosis and management of LVAD-associated coagulopathy and to provide expert recommendations for clinical practice.

Recent Findings
In patients undergoing LVAD implantation, the severity of coagulopathy is directly related to the severity of the cardiac failure. The evidence from current literature for optimal management of acquired coagulopathy during and after LVAD implantation is sparse. The traditional transfusion strategy of replacing coagulation factors with fresh frozen plasma involves the risk of transfusion-associated circulatory overload. Current recommendations for targeted replacement of coagulation factors with 4-factor prothrombin concentrate and fibrinogen concentrate in cardiac surgery may be translated in this special setting.

Summary
The targeted, point-of-care use of concentrated coagulation factors may improve treatment of severe acquired coagulopathy during LVAD implantation and in LVAD patients needing urgent non-cardiac surgery.
Severe allergic reactions after COVID-19 vaccination with the Pfizer/BioNTech vaccine in Great Britain and USA
Authors: Klimek Ludger , Novak Natalija , Hamelmann Eckard , Werfel Thomas , Wagenmann Martin , Taube Christian , Bauer Andrea , Merk Hans , Rabe Uta , Jung Kirsten , Schlenter Wolfgang , Ring Johannes , Chaker Adam , Wehrmann Wolfgang , Becker Sven , Mülleneisen Norbert , Nemat Katja , Czech Wolfgang , Wrede Holger , Brehler Randolf , Fuchs Thomas , Jakob Thilo , Ankermann Tobias , Schmidt Sebastian M. , Gerstlauer Michael , Vogelberg Christian , Zuberbier Thomas , Hartmann Karin , Worm Margitta 
Published: February 2021

SummaryTwo employees of the National Health Service (NHS) in England developed severe allergic reactions following administration of BNT162b2 vaccine against COVID-19 (coronavirus disease 2019). The British SmPC for the BNT162b2 vaccine already includes reference to a contraindication for use in individuals who have had an allergic reaction to the vaccine or any of its components. As a precautionary measure, the Medicines and Healthcare products Regulatory Agency (MHRA) has issued interim guidance to the NHS not to vaccinate in principle in “patients with severe allergies”. Allergic reactions to vaccines are very rare, but vaccine components are known to cause allergic reactions. BNT162b2 is a vaccine based on an mRNA embedded in lipid nanoparticles and blended with other substances to enable its transport into the cells. In the pivotal phase III clinical trial, the BNT162b2 vaccine was generally well tolerated, but this large clinical trial, used to support vaccine approval by the MHRA and US Food and Drug Administration, excluded individuals with a “history of a severe adverse reaction related to the vaccine and/or a severe allergic reaction (e.g., anaphylaxis) to a component of the study medication”. Vaccines are recognized as one of the most effective public health interventions. This repeated administration of a foreign protein (antigen) necessitates a careful allergological history before each application and diagnostic clarification and a risk–benefit assessment before each injection. Severe allergic reactions to vaccines are rare but can be life-threatening, and it is prudent to raise awareness of this hazard among vaccination teams and to take adequate precautions while more experience is gained with this new vaccine.
Intelligent IoT systems for civil infrastructure health monitoring: a research roadmap
Authors: Bertino E. , Jahanshahi M. R. , Singla A. , Wu R.-T. 
Published: February 2021

AbstractThis paper addresses the problem of efficient and effective data collection and analytics for applications such as civil infrastructure monitoring and emergency management. Such problem requires the development of techniques by which data acquisition devices, such as IoT devices, can: (a) perform local analysis of collected data; and (b) based on the results of such analysis, autonomously decide further data acquisition. The ability to perform local analysis is critical in order to reduce the transmission costs and latency as the results of an analysis are usually smaller in size than the original data. As an example, in case of strict real-time requirements, the analysis results can be transmitted in real-time, whereas the actual collected data can be uploaded later on. The ability to autonomously decide about further data acquisition enhances scalability and reduces the need of real-time human involvement in data acquisition processes, especially in contexts with critical real-time requirements. The paper focuses on deep neural networks and discusses techniques for supporting transfer learning and pruning, so to reduce the times for training the networks and the size of the networks for deployment at IoT devices. We also discuss approaches based on machine learning reinforcement techniques enhancing the autonomy of IoT devices.
A Systematic Review on Sexual Boredom
Authors: de Oliveira Leonor , Carvalho Joana , Nobre Pedro 
Published: February 2021

ABSTRACTBackgroundEmpirical data on sexual boredom are scarce and unsystematized, contrasting with the literature on general boredom.AimThe aim of this review of literature is to verify how sexual boredom is defined in previous research and which relationships were found with sexual functioning, relationship dynamics, or gender.MethodsA systematic search was conducted in EBSCO, Scopus, Web of Science, and PubMed databases for papers published until August 2020. Search terms used were “sexual boredom” or “sexual tedium” or “sexual indifference” or “sexual monotony” or a combination of “boredom” and “sexual activity” or “intercourse”. This systematic review followed PRISMA guidelines.OutcomesArticles were grouped in general boredom and sexuality research and in sexual boredom research.RESULTSThis review consists of 43 articles, of which 31 are quantitative studies, 8 are qualitative studies, and 4 are mixed-method studies. Studies concerning general boredom and sexuality include research on diverse aspects of sexual behavior, namely solitary sexual behavior, extra-dyadic sex, compulsive sexual behavior, and risky sexual behavior. Sexual boredom research included papers regarding personality, sexual response, and varied aspects of sexual behavior.Clinical ImplicationsFindings suggest sexual boredom is related with sexual response, sexual satisfaction, and hypersexuality, which renders clinical relevance. Sexual boredom impacts well-being, and further research should focus on exploring potential mechanisms underpinning this sexual problem.Strengths and limitationsTo the authors’ knowledge, this is the only existing systematic review of sexual boredom and allowed identifying key features of sexual boredom and related aspects. However, because most studies are correlational, and several do not use comprehensive measures of sexual boredom, no causal relationships were identified.CONCLUSIONThis review indicates the construct of sexual boredom includes individual, relationship, and societal aspects. However, no definition of sexual boredom includes these, and current knowledge does not allow formulating a model or a theory of sexual boredom.
Design at hackathons: new opportunities for design research
Authors: Flus Meagan , Hurst Ada 
Published: February 2021

AbstractHackathons are short-term events at which participants work in small groups to ideate, develop and present a solution to a problem. Despite their popularity, and significant relevance to design research, they have only recently come into research focus. This study presents a review of the existing literature on the characteristics of designing at hackathons. Hackathon participants are found to follow typical divergence–convergence patterns in their design process throughout the hackathon. Unique features include the initial effort to form teams and the significant emphasis on preparing and delivering a solution demo at the final pitch. Therefore, hackathons present themselves as a unique setting in which design is conducted and learned, and by extension, can be studied. Overall, the review provides a foundation to inform future research on design at hackathons. Methodological limitations of current studies on hackathons are discussed and the feasibility of more systematic studies of design in these types of settings is assessed. Further, we explore how the unique nature of the hackathon format and the diverse profiles of hackathon participants with regards to subject matter knowledge, design expertise and prior hackathon experience may affect design cognition and behaviour at each stage of the design process in distinctive ways.