bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retro-patellar approach in telescopic nailing of the tibia in children with osteogenesis imperfecta
Authors: Erdal Ozan A. , Gorgun Baris , Sarikaya Ilker A. , Inan Muharrem 
Published: July 2021

Purpose Telescopic intramedullary nailing (TN) has become the main choice of treatment in children with osteogenesis imperfecta (OI). The classical parapatellar tibial nailing technique poses difficulties in maintaining reduction, insertion of the nail and fluoroscopic imaging. Also, deformities of the proximal tibia in relatively small children with OI can be problematic for tibial nailing. In this report, we present the retro-patellar approach in tibial TN of children with OI as an alternative to the classical approach and report the early radiographic and clinical results of our patients. Methods The nail is inserted through a skin incision proximal to the patella, passing inside the patellofemoral joint while the knee is positioned to 15° to 20° of flexion. In total, 30 tibiae of 15 patients had been operated and were reviewed after at least one year of follow-up. Any complications, such as implant failure, joint damage or instability, malunion, nonunion or refracture, were recorded. Results The mean age of our patients was 8.5 years, and the mean follow-up period was 27 months. There were no complaints involving the knee. All patients showed complete union without any implant failure or refracture. We did not observe any nail protrusion, bending or loss of correction during the procedure. Conclusion The retro-patellar approach for tibial TN appears to be safe and effective in patients with OI. Level of Evidence IV
Dyadic Green’s function for the graphene–dielectric stack with arbitrary field and source points
Authors: Hayati Raad Shiva , Atlasbaf Zahra , Cuevas Mauro 
Published: July 2021

In this paper, the dyadic Green’s function for a graphene–dielectric stack is formulated based on the scattering superposition method. To this end, the scattering Green’s function in each layer is expanded in terms of cylindrical vector wave functions with unknown coefficients. Using the Kronecker delta function in the field expansion, it is considered that the field and source points lie in the arbitrary layers. Afterward, recurrence relations to calculate the unknown expansion coefficients are derived by applying the impedance boundary condition at the interface of a graphene sheet surrounded by two adjacent dielectric layers. The verification of the calculated coefficients is conducted by using them in the analysis of graphene-based structures with different numbers of layers, including (1) free-standing frequency-selective surfaces and (2) parallel plates with graphene walls. A potential application of our proposed structure is investigating the interaction of donor–acceptor pairs residing in the arbitrary layers of the graphene–dielectric stack with a desired number of layers.
Dual-mode broadband compact 2 × 2 optical power splitter using sub-wavelength metamaterial structures
Authors: Shiran Hatef , zhang Guowu , Liboiron-Ladouceur Odile 
Published: July 2021

The multimode power splitter is a fundamental component in mode-division multiplexed systems. In this paper, we design and characterize a broadband compact dual-mode multimode interferometer (MMI) optical power splitter based on subwavelength grating (SWG) structures. The optimized dual-mode MMI is three times more compact than its conventional mode insensitive MMIs and shows low loss and low crosstalk flat response over 100 nm bandwidth. Characterizations of the fabricated dual-mode splitter show that the total excess loss in the experiment is less than 0.1 dB and 0.65 dB for TE0 and TE1, respectively, and the modal crosstalk is less than -17 dB for both input modes.
Evaluation of the Abbott ARCHITECT HIV Ag/Ab combo assay for determining recent HIV-1 infection
Authors: Curtis Kelly A. , Rudolph Donna L. , Pan Yi , Delaney Kevin , Anastos Kathryn , DeHovitz Jack , Kassaye Seble G. , Hanson Carl V. , French Audrey L. , Golub Elizabeth , Adimora Adaora A. , Ofotokun Igho , Bolivar Hector , Kempf Mirjam-Colette , Peters Philip J. , Switzer William M. 
Published: July 2021

Background
Given the challenges and costs associated with implementing HIV-1 incidence assay testing, there is great interest in evaluating the use of commercial HIV diagnostic tests for determining recent HIV infection. A diagnostic test with the capability of providing reliable data for the determination of recent HIV infection without substantial modifications to the test protocol would have a significant impact on HIV surveillance. The Abbott ARCHITECT HIV Ag/Ab Combo Assay is an antigen/antibody immunoassay, which meets the criteria as the first screening test in the recommended HIV laboratory diagnostic algorithm for the United States.

Methods
In this study, we evaluated the performance characteristics of the ARCHITECT HIV Ag/Ab Combo signal-to-cutoff ratio (S/Co) for determining recent infection, including estimation of the mean duration of recent infection (MDRI) and false recent rate (FRR), and selection of recency cutoffs.

Results
The MDRI estimates for the S/Co recency cutoff of 400 is within the 4 to 12 months range recommended for HIV incidence assays, and the FRR rate for this cutoff was 1.5%. Additionally, ARCHITECT Combo S/Co values were compared relative to diagnostic test results from two prior prospective HIV-1 diagnostic studies in order to validate the use of the S/Co for both diagnostic and recency determination.

Conclusion
Dual-use of the ARCHITECT Combo assay data for diagnostic and incidence purposes would reduce the need for separate HIV incidence testing and allow for monitoring of recent infection for incidence estimation and other public health applications.
Access experiences and attitudes toward abortion among youth experiencing homelessness in the United States: A systematic review
Authors: Munro Sarah , Benipal Savvy , Williams Aleyah , Wahl Kate , Trenaman Logan , Begun Stephanie 
Published: July 2021

ObjectivesWe sought to review the literature on the access experiences and attitudes toward abortion among youth experiencing homelessness in the United States.MethodsWe conducted a systematic review of peer‐reviewed literature published from 2001 to 2019. We included qualitative studies involving US participants that focused on access experiences, views, or accounts of unintended pregnancy and/or abortion among youth experiencing homelessness. We excluded studies published before 2001 as that was the year mifepristone medication abortion was made available in the US and we aimed to investigate experiences of access to both medical and surgical abortion options.ResultsOur thematic analysis of the data resulted in five key themes that characterize the abortion attitudes and access experiences of youth experiencing homelessness: (1)engaging in survival sex and forced sex, (2)balancing relationships and autonomy, (3)availability does not equal access, (4)attempting self-induced abortions using harmful methods, and (5)feeling resilient despite traumatic unplanned pregnancy experiences.ConclusionsYouth experiencing homelessness experience barriers to abortion access across the US, including in states with a supportive policy context and publicly funded abortion services. In the absence of accessible services, youth may consider harmful methods of self-induced abortion. Improved services should be designed to offer low-barrier abortion care with the qualities that youth identified as important to them, including privacy and autonomy.
Validation of the indication for colposcopy proposed by the 2019 ASCCP risk-based management consensus guidelines: A single-center study in China
Authors: Gui Ting , Chen Zhiyan , Chen Fei 
Published: July 2021

Objective
To validate the colposcopy indication proposed by the 2019 ASCCP Risk-Based Management Consensus Guidelines for abnormal cervical cancer screening tests (the 2019 ASCCP guidelines).

Methods
Clinical data of 1404 patients who underwent colposcopy in single center in China were reviewed. Based on history and current cervical screening (HPV & cytology), corresponding recommendations were given according to the 2019 ASCCP guidelines. The agreement and discrepancy of colposcopy indication were analyzed between the Chinese consensus and the 2019 ASCCP guidelines.

Results
Colposcopy indication was matched in about 80% patients. The left 20% were recommended with follow-up by the 2019 ASCCP guidelines. The discrepancy mainly focused on patients having a current result of HPV-positive NILM without unknown history. The ratio of observed CIN3+ in our database over estimated CIN3+ by the 2019 ASCCP guidelines was 6.2 (31/5). The ratio was even higher in patients with HPV16/18-positive NILM (7, 28/4), compared with those with other types of high-risk HPV-positive NILM (3, 3/1). The 2019 ASCCP guidelines had a relatively high sensitivity (83.1%), a low specificity (21.5%), a low positive predictive value (14.1%) and a high negative predictive value (89.1%) for prediction of CIN 3+.

Conclusions
We could try to apply the 2019 ASCCP guidelines in Chinese population. The classification of HR-HPV was strongly recommended during risk assessment. For patients with HPV16/18 infection, colposcopy should be recommended. Perspective multi-center randomized controlled trial with reliable follow-up should be performed in the future to confirm the feasibility.
A transfer learning approach to facilitate ComBat-based harmonization of multicentre radiomic features in new datasets
Authors: Da-ano Ronrick , Lucia François , Masson Ingrid , Abgral Ronan , Alfieri Joanne , Rousseau Caroline , Mervoyer Augustin , Reinhold Caroline , Pradier Olivier , Schick Ulrike , Visvikis Dimitris , Hatt Mathieu 
Published: July 2021

Purpose
To facilitate the demonstration of the prognostic value of radiomics, multicenter radiomics studies are needed. Pooling radiomic features of such data in a statistical analysis is however challenging, as they are sensitive to the variability in scanner models, acquisition protocols and reconstruction settings, which is often unavoidable in a multicentre retrospective analysis. A statistical harmonization strategy called ComBat was utilized in radiomics studies to deal with the “center-effect”. The goal of the present work was to integrate a transfer learning (TL) technique within ComBat—and recently developed alternate versions of ComBat with improved flexibility (M-ComBat) and robustness (B-ComBat)–to allow the use of a previously determined harmonization transform to the radiomic feature values of new patients from an already known center.

Material and methods
The proposed TL approach were incorporated in the four versions of ComBat (standard, B, M, and B-M ComBat). The proposed approach was evaluated using a dataset of 189 locally advanced cervical cancer patients from 3 centers, with magnetic resonance imaging (MRI) and positron emission tomography (PET) images, with the clinical endpoint of predicting local failure. The impact performance of the TL approach was evaluated by comparing the harmonization achieved using only parts of the data to the reference (harmonization achieved using all the available data). It was performed through three different machine learning pipelines.

Results
The proposed TL technique was successful in harmonizing features of new patients from a known center in all versions of ComBat, leading to predictive models reaching similar performance as the ones developed using the features harmonized with all the data available.

Conclusion
The proposed TL approach enables applying a previously determined ComBat transform to new, previously unseen data.
Impact of metabolic syndrome and its components on bone remodeling in adolescents
Authors: Nóbrega da Silva Valéria , Goldberg Tamara Beres Lederer , Silva Carla Cristiane , Kurokawa Cilmery Suemi , Fiorelli Luciana Nunes Mosca , Rizzo Anapaula da Conceição Bisi , Corrente José Eduardo 
Published: July 2021

Introduction
Osteoporosis and metabolic syndrome (MetS) are diseases that have serious public health consequences, reducing the quality of life of patients and increasing morbidity and mortality, with substantial healthcare expenditures.

Objective
To evaluate the impact of MetS on bone mineral density (BMD) and biochemical markers of bone formation and resorption in adolescents with excess weight.

Method
A descriptive and analytical cross-sectional study was performed that evaluated 271 adolescents of both sexes (10 to 16 years). From the total sample, 42 adolescents with excess weight and the presence of MetS (14%) were selected. A further 42 adolescents with excess weight and without MetS were chosen, matched for chronological age, bone age, and pubertal developmental criteria to those with MetS, for each sex. Anthropometric measurements, blood pressure collection, and biochemical tests were performed in all adolescents, as well as evaluation of BMD and the bone biomarkers osteocalcin (OC), bone alkaline phosphatase (BAP), and carboxy-terminal telopeptide (S-CTx).

Results
The adolescents with excess weight and MetS exhibited significantly lower transformed BMD and concentrations of BAP, OC, and S-CTx compared to the matched group, except for OC in boys. A negative and significant correlation was observed between total body BMD and BAP (r = -0.55568; p = 0.005), OC (r = -0.81760; p = < .000), and S-CTx (r = -0.53838; p = 0.011) in girls.

Conclusion
Metabolic syndrome may be associated with reduced bone mineral density and biochemical markers of bone formation and resorption in adolescents with excess weight.
Evaluating the vector competence of Aedes simpsoni sl from Kenyan coast for Ngari and Bunyamwera viruses
Authors: Mutisya James , Kahato Michael , Mulwa Francis , Langat Solomon , Chepkorir Edith , Arum Samuel , Tchouassi David , Sang Rosemary , Lutomiah Joel 
Published: July 2021

Background
Bunyamwera(BUNV) and Ngari (NGIV) viruses are arboviruses of medical importance globally, the viruses are endemic in Africa, Aedes(Ae) aegypti and Anopheles(An) gambiae mosquitoes are currently competent vectors for BUNV and NGIV respectively. Both viruses have been isolated from humans and mosquitoes in various ecologies of Kenya. Understanding the risk patterns and spread of the viruses necessitate studies of vector competence in local vector population of Ae. simpsoni sl which is abundant in the coastal region. This study sought to assess the ability of Ae. Simpsoni sl mosquitoes abundant at the Coast of Kenya to transmit these viruses in experimental laboratory experiments.

Methods
Field collected larvae/pupae of Ae. Simpsoni sl mosquitoes from Rabai, Kilifi County, were reared to adults, the first filial generation (F0) females’ mosquitoes were orally exposed to infectious blood meal with isolates of the viruses using the hemotek membrane feeder. The exposed mosquitoes were incubated under insectary conditions and sampled on day 7, 14 and 21days post infection to determine susceptibility to the virus infection using plaque assay.

Results
A total of 379 (Bunyamwera virus 255 and Ngari virus 124) Ae. simpsoni sl were orally exposed to infectious blood meal. Overall, the infection rate (IR) for BUNV and NGIV were 2.7 and 0.9% respectively. Dissemination occurred in 5 out 7 mosquitoes with mid-gut infection for Bunyamwera virus and 1 out of 2 mosquitoes with mid-gut infection for Ngari virus. Further, the transmission was observed in 1 out of 5 mosquitoes that had disseminated infection and no transmission was observed for Ngari virus in all days post infection (dpi).

Conclusion
Our study shows that Ae. simpsoni sl. is a laboratory competent vector for Bunyamwera virus since it was able to transmit the virus through capillary feeding while NGIV infection was restricted to midgut infection and disseminated infection, these finding adds information on the epidemiology of the viruses and vector control plan.
Reweighting a Swedish health questionnaire survey using extensive population register and self-reported data for assessing and improving the validity of longitudinal associations
Authors: Nilsson Anton , Bonander Carl , Strömberg Ulf , Canivet Catarina , Östergren Per-Olof , Björk Jonas 
Published: July 2021

Background
In cohorts with voluntary participation, participants may not be representative of the underlying population, leading to distorted estimates. If the relevant sources of selective participation are observed, it is however possible to restore the representativeness by reweighting the sample to resemble the target population. So far, few studies in epidemiology have applied reweighting based on extensive register data on socio-demographics and disease history, or with self-reported data on health and health-related behaviors.

Methods
We examined selective participation at baseline and the first two follow-ups of the Scania Public Health Cohort (SPHC), a survey conducted in Southern Sweden in 1999/2000 (baseline survey; n = 13,581 participants, 58% participation rate), 2005 (first follow-up, n = 10,471), and 2010 (second follow-up; n = 9,026). Survey participants were reweighted to resemble the underlying population with respect to a broad range of socio-demographic, disease, and health-related characteristics, and we assessed how selective participation impacted the validity of associations between self-reported overall health and dimensions of socio-demographics and health.

Results
Participants in the baseline and follow-up surveys were healthier and more likely to be female, born in Sweden, middle-aged, and have higher socioeconomic status. However, the differences were not very large. In turn, reweighting the samples to match the target population had generally small or moderate impacts on associations. Most examined regression coefficients changed by less than 20%, with virtually no changes in the directions of the effects.

Conclusion
Overall, selective participation with respect to the observed factors was not strong enough to substantially alter the associations with self-assessed health. These results are consistent with an interpretation that SPHC has high validity, perhaps reflective of a relatively high participation rate. Since validity must be determined on a case-by-case basis, however, researchers should apply the same method to other health cohorts to assess and potentially improve the validity.
Knowledge, attitude, practice and associated factors towards patient safety among nurses working at Asella Referral and Teaching Hospital, Ethiopia: A cross-sectional study
Authors: Wake Addisu Dabi , Tuji Techane Sisay , Gonfa Berhanu Kebe , Waldekidan Eskeder Tsehayu , Beshaw Etalem Demise , Mohamed Mohamed Ahimad , Geressu Shawlem Tadese 
Published: July 2021

Background
Patient safety has been identified as a global priority area. It is one of the most health care challenges. There is a rising number of patients’ mortality in hospitals each year because of lapses in patient safety practice. Therefore, the purpose of the present study was to assess knowledge, attitude, practice, and associated factors towards patient safety among nurses working at Asella Referral and Teaching Hospital.

Methods
Institution based cross-sectional study was conducted on 172 nurses working at Asella Referral and Teaching Hospital, Arsi Zone, Oromia Regional State, Ethiopia. The data were collected from nurses from December 28, 2020 to January 05, 2021 by using a pretested questionnaire. The data were entered into Epi-Data version 4.2.0.0 and analyzed using the SPSS version 23.0 software.

Results
A total of 172 nurses were enrolled in to the study, resulting a response rate of 99.4%. The mean age of the nurses was 32.53 years. More than half 94(54.7%) of them were female. The majority 133(77.3%) of them were qualified for degrees and above. The majority 155(90.1%) of them had working experience of ≤13years. The nurse’s level of good knowledge, positive attitude, and good practice towards patient safety was 58.7% (n = 101, [95% CI; 51.7, 66.7]), 52.9% (n = 91, [95% CI; 43.6, 61.4]), and 50% (n = 86, [95% CI; 43.6, 57%]) respectively. The multivariable logistic regression analysis showed; working in the operation theatre unit [AOR = 5.01, 95% CI; 1.36, 18.46], having information on patient safety during initial education [AOR = 4.99, 95%CI; 1.87, 13.31], and having information on patient safety during continuing education [AOR = 2.85, 95% CI; 1.14, 7.12] were factors significantly associated with knowledge towards patient safety. Being male [AOR = 3.09, 95% CI; 1.38, 6.95], having working experience of >13 years [AOR = 8.37, 95% CI; 1.36, 51.70], having information on patient safety during initial education [AOR = 3.36, 95%CI; 1.11, 10.15], having information on patient safety during continuing education [AOR = 3.33, 95% CI; 1.25, 8.85], and having good Knowledge towards patient safety [AOR = 2.74, 95% CI; 1.21, 6.21] were factors significantly associated with attitude towards patient safety. Having information on patient safety during initial education [AOR = 5.35, 95%CI; 1.77, 16.17] and having a positive attitude towards patient safety [AOR = 3.02, 95% CI; 1.32, 6.91] were factors significantly associated with practice towards patient safety.

Conclusion
In the present study, more than half of the nurse’s had good knowledge and positive attitude towards patient safety. However, only half of the nurses had good practice towards patient safety. Educational programs and training on patient safety may need to take place for nurses to abate these problems.
Imágenes míticas y oníricas: un análisis desde La psicología arquetipal
Authors: Da Silva Filho José Francisco 
Published: July 2021

Para desarrollar este artículo nos respaldamos en la psicología arquetipal y, fundamentalmente, en las obras de James Hillman, su principal representante. Nuestro objetivo con este trabajo es reexaminar su pensamiento y revisar en sus textos las ideas fundamentales que giran alrededor de las imágenes míticas y oníricas, las cuales representan un distanciamiento de los estrechos modelos racionales y tradicionales aún vigentes. Elegimos a priori algunas direcciones teóricas de la mitopoética para orientar esa investigación sobre las imágenes, así que vamos a dar énfasis también a autores como Mircea Eliade, Ernst Cassirer y Gaston Bachelard que abordan este tema desde una perspectiva más mítico-simbólica.