bluuebunny/crossref_metadata_2025_split huggingface dataset:
The level of satisfaction with their work and degree of burnout among anesthesiologists and emergency physicians working in the red zone of a COVID hospital
Authors: Malyarchikov А. V. , Shapovalov K. G. 
Published: May 2021

The objective: To determine the level of satisfaction with their work and degree of burnout among anesthesiologists and emergency physicians working in the red zone of a COVID-19 hospital.Subjects and methods. A prospective study was conducted as an anonymous survey of physicians performing their duties in intensive care units of the red zone. 65 specialists were interviewed: Group 1 (52.3%) – trainee physicians, Group 2 (47.7%) – anesthesiologists and emergency physicians.Results. The majority of respondents in both groups noted relatively high satisfaction with their current work. At the same time, the majority of respondents (70.9%) in the group of anesthesiologists and emergency physicians would prefer the previous working conditions to current ones. Also, it was noted that both groups were highly emotionally exhausted.
Refractory septic shock (Part 1)
Authors: Plotkin L. L. 
Published: May 2021

Refractory septic shock develops in 6–7% of sepsis patients with short-term lethality rate of more than 50%. It is necessary to assess the effectiveness of intensive therapy methods used in this case.The objective of the review: to analyze publications on the intensive care of refractory septic shock.Results. 56 studies published in the period from January 1, 1990 to September 1, 2020 were analysed, they reflect the effectiveness of some methods used for management of refractory septic shock (treatment of the underlying disease, liquid bolus, the use of norepinephrine, adjuvant therapy, management of metabolic acidosis). The second part of this article will reflect the evaluation of the effectiveness of other approaches to the treatment of this complication.
A clinical case of anaphylactic shock development after anesthesia induction
Authors: Khrapov K. N. , Khryapa A. A. , Vartanova I. V. , Sedov S. S. , Okhapina Yu. S. , Gavrilova E. G. 
Published: May 2021

The article describes a clinical case when a patient who was supposed to have a planned surgery on the spine developed anaphylactic shock. After 10 minutes of anesthesia introduction, the patient developed severe hypotension (resistant to the administration of adrenomimetics) and tachycardia; a decrease in the partial pressure of carbon dioxide at the end of expiration was noted. Due to the rapid development of a critical condition, the absence of specific skin manifestations and allergic history, as well as a direct association with the administration of a specific agent, it was necessary to carry out a differential diagnosis between acute myocardial infarction, pulmonary embolism, and anaphylactic shock. During the intensive care, the patient had echocardiography and ECG, blood gases were tested; the decisive diagnostic factor was the identification of bronchospasm signs. When the condition was stabilized, angiography of the vessels of the heart and lungs was performed; later, the agent that caused the development of anaphylaxis was established.Identifying the cause of hypotension after induction of anesthesia is critical because therapy can vary significantly. The development of anaphylactic shock during general anesthesia is not common but delayed diagnosis and therapy can be fatal. The article discusses modern approaches to the diagnosis and therapy of perioperative anaphylaxis using the example of the presented clinical case.
Feasibility of using smart meter water consumption data and in-sewer flow observations for sewer system analysis: a case study
Authors: Lund N. S. V. , Kirstein J. K. , Madsen H. , Mark O. , Mikkelsen P. S. , Borup M. 
Published: May 2021

Abstract
Globally, smart meters measuring the water consumption with a high temporal resolution at consumers' households are deployed at an increasing rate. In addition to their use for billing or leak detection purposes, smart meters may provide detailed knowledge of the wastewater inflow to the sewer systems in space and time and open up new types of system analyses aimed at closing the urban water balance. In this study, we first validate the smart meter data against other, independent water distribution data. Subsequently, we use a detailed hydrodynamic sewer system model to link the smart meter data from almost 2,000 consumers with in-sewer flow observations in order to simulate the wastewater component of the dry weather flow (DWF) and to identify potential anomalies. Results show that it is feasible to use smart meter data as input to a distributed urban drainage model, as the temporal dynamics of the model results and in-sewer flow observations match well. Furthermore, the study suggests that in-sewer flow observations may be subject to unrecognised uncertainties, which make them unsuitable for advanced investigations of the DWF composition, and this underlines the necessity of collecting data from independent sources. The study also exemplifies that digital system integration in the water sector may be complicated. However, overcoming these obstacles may improve both offline and real-time urban drainage management.
Cytotoxicity, Anti-diabetic, and Hepato-protective Potential of Ajuga
bracteosa-conjugated Silver Nanoparticles in Balb/c Mice
Authors: Nazer Sadia , Andleeb Saiqa , Ali Shaukat , Gulzar Nazia , Raza Abida , Khan Habib , Akhtar Kalsoom , Ahmed Muhammad Naeem 
Published: May 2021

Background:
Ajuga bracteosa is a traditional herb used against various diseases.

Objective:
Current research aimed to investigate the anti-diabetic and hepato-protective effect of green synthesized silver nanoparticles (ABAgNPs) using Ajuga bracteosa aqueous extract (ABaqu).

Methods:
In vitro anti-diabetic and cytotoxic effects were carried out via α- glucosidase inhibition, brine shrimp lethality, and protein kinase inhibition assays. For in vivo screening of 200 mg/kg and 400 mg/kg of both ABAgNPs and ABaqu in alloxan-induced and CCl4-induced Swiss albino mice were used. Liver and kidney functional markers, hematology, and histopathological studies were carried out after 14 days of administration.

Results:
In vivo antidiabetic and anti-cancerous effects showed valuable anti-hyperglycemic and hepato-protective potential when mice were treated with ABaqu and ABAgNPs. A significant reduction in the blood glucose level was recorded when ABaqu and ABAgNPs were administrated orally compared to Glibenclamide treated group. Significant reduction in ALT, AST, ALP, urea, uric acid, and creatinine was recorded in ABaqu and ABAgNPs treated diabetic mice. The hepato-protective findings indicated that ALT, ALP, AST were elevated in CCl4-induced mice while declined in both ABAgNPs and ABaqu treated CCl4-induced mice. Histopathological examination revealed that ABAgNPs have hepato-protective activity.

Conclusion:
It was concluded that ABAgNPs and ABaqu possessed strong anti-diabetic and hepato-protective phytoconstituents, which could be used in the prevention of diseases.
Acutil® in Mild Cognitive Impairment or Early Dementia: An Exploratory Observational Pilot Study
Authors: Rainer Michael , Mucke Hermann A.M. 
Published: May 2021

Background:
With no approved treatment for mild cognitive impairment
(MCI), attention increasingly turns to qualified food supplements.

Objective:
To conduct a 12-month rater-blinded exploratory outpatient trial with Acutil®,
a supplement consisting of ω-3 polyunsaturated fatty acids, Ginkgo biloba extract, and
vitamins, in 50 persons with amnestic MCI or mild to moderate Alzheimer or mixed-type
dementia.

Methods:
The used cognitive tools were the Alzheimer's Disease Assessment Scale-
Cognitive Subscale (ADAS-Cog), the Mini-Mental State Exam (MMSE), and Controlled
Oral Word Association Test (COWAT). Patients were randomized in the ratio of 40:10 to
additional Acutil® or no additional supplementation; all continued on their existing medications
during the entire study.

Results:
Only the COWAT produced a clear positive signal in the Acutil® group between
individual baseline and study endpoint, but the between-group comparison was not statistically
significant. The MMSE score remained stable in the Acutil® group while deteriorating
in the control group; post hoc examination suggests that the Acutil® group might
have contained responders. The ADAS-Cog and Clinical Dementia Rating (CDR) scores
showed marginal deterioration in both groups.

Conclusions:
We tentatively interpret our results as potentially indicating positive effects of
Acutil® on verbal fluency and some aspects of executive function, with an onset after 6
months of continuous treatment. However, much larger and double-blinded studies will be
required to make firm statements.
Developing an Automatic System for Classifying Chatter About Health Services on Twitter: Case Study for Medicaid
Authors: Yang Yuan-Chi , Al-Garadi Mohammed Ali , Bremer Whitney , Zhu Jane M , Grande David , Sarker Abeed 
Published: May 2021

Background
The wide adoption of social media in daily life renders it a rich and effective resource for conducting near real-time assessments of consumers’ perceptions of health services. However, its use in these assessments can be challenging because of the vast amount of data and the diversity of content in social media chatter.

Objective
This study aims to develop and evaluate an automatic system involving natural language processing and machine learning to automatically characterize user-posted Twitter data about health services using Medicaid, the single largest source of health coverage in the United States, as an example.

Methods
We collected data from Twitter in two ways: via the public streaming application programming interface using Medicaid-related keywords (Corpus 1) and by using the website’s search option for tweets mentioning agency-specific handles (Corpus 2). We manually labeled a sample of tweets in 5 predetermined categories or other and artificially increased the number of training posts from specific low-frequency categories. Using the manually labeled data, we trained and evaluated several supervised learning algorithms, including support vector machine, random forest (RF), naïve Bayes, shallow neural network (NN), k-nearest neighbor, bidirectional long short-term memory, and bidirectional encoder representations from transformers (BERT). We then applied the best-performing classifier to the collected tweets for postclassification analyses to assess the utility of our methods.

Results
We manually annotated 11,379 tweets (Corpus 1: 9179; Corpus 2: 2200) and used 7930 (69.7%) for training, 1449 (12.7%) for validation, and 2000 (17.6%) for testing. A classifier based on BERT obtained the highest accuracies (81.7%, Corpus 1; 80.7%, Corpus 2) and F1 scores on consumer feedback (0.58, Corpus 1; 0.90, Corpus 2), outperforming the second best classifiers in terms of accuracy (74.6%, RF on Corpus 1; 69.4%, RF on Corpus 2) and F1 score on consumer feedback (0.44, NN on Corpus 1; 0.82, RF on Corpus 2). Postclassification analyses revealed differing intercorpora distributions of tweet categories, with political (400778/628411, 63.78%) and consumer feedback (15073/27337, 55.14%) tweets being the most frequent for Corpus 1 and Corpus 2, respectively.

Conclusions
The broad and variable content of Medicaid-related tweets necessitates automatic categorization to identify topic-relevant posts. Our proposed system presents a feasible solution for automatic categorization and can be deployed and generalized for health service programs other than Medicaid. Annotated data and methods are available for future studies.
The Effect of Test Timing on the Probability of Positive SARS-CoV-2 Swab Test Results: Mixed Model Approach
Authors: Benoni Roberto , Panunzi Silvia , Campagna Irene , Moretti Francesca , Lo Cascio Giuliana , Spiteri Gianluca , Porru Stefano , Tardivo Stefano 
Published: May 2021

Background
During the COVID-19 pandemic, swab tests proved to be effective in containing the infection and served as a means for early diagnosis and contact tracing. However, little evidence exists regarding the correct timing for the execution of the swab test, especially for asymptomatic individuals and health care workers.

Objective
The objective of this study was to analyze changes in the positive findings over time in individual SARS-CoV-2 swab tests during a health surveillance program.

Methods
The study was conducted with 2071 health care workers at the University Hospital of Verona, with a known date of close contact with a patient with COVID-19, between February 29 and April 17, 2020. The health care workers underwent a health surveillance program with repeated swab tests to track their virological status. A generalized additive mixed model was used to investigate how the probability of a positive test result changes over time since the last known date of close contact, in an overall sample of individuals who tested positive for COVID-19 and in a subset of individuals with an initial negative swab test finding before being proven positive, to assess different surveillance time intervals.

Results
Among the 2071 health care workers in this study, 191 (9.2%) tested positive for COVID-19, and 103 (54%) were asymptomatic with no differences based on sex or age. Among 49 (25.7%) cases, the initial swab test yielded negative findings after close contact with a patient with COVID-19. Sex, age, symptoms, and the time of sampling were not different between individuals with an initial negative swab test finding and those who initially tested positive after close contact. In the overall sample, the estimated probability of testing positive was 0.74 on day 1 after close contact, which increased to 0.77 between days 5 and 8. In the 3 different scenarios for scheduled repeated testing intervals (3, 5, and 7 days) in the subgroup of individuals with an initially negative swab test finding, the probability peaked on the sixth, ninth and tenth, and 13th and 14th days, respectively.

Conclusions
Swab tests can initially yield false-negative outcomes. The probability of testing positive increases from day 1, peaking between days 5 and 8 after close contact with a patient with COVID-19. Early testing, especially in this final time window, is recommended together with a health surveillance program scheduled in close intervals.
Revealing Millennials’ Networks in Discussing Maritime Issues within the Triple Helix of University-Industry-Government
Authors: Setiadi Tatak 
Published: May 2021

Millennials' networks within the triple helix of University-Industry-Government show unusual communication structures and are challenging to be revealed. Using the direct and online written interview with the millennials found about 817 relations (edges) to 347 actors (nodes) in total. Analysis by Social Network Analysis (SNA) found: (1) the dominant issues of the maritime human resources are about future work prospects and specialties field, imbalance of supply and demand of maritime human resources, and improvement needed of industry's human resources (2) the dominant skill issue is capacity building and continuous learning, (3) the highest degree of centrality and closeness centrality has resulted from Industry, (4) the highest betweenness centrality and eigenvector centrality has resulted from University, (5) there is moderate positive correlation of ages to closeness centrality and weak negative correlation to eigenvector centrality, (6) there is a moderate positive correlation of education levels to closeness centrality, (7) there is a weak negative correlation of gender to eigenvector centrality, and (8) there is a statist relation of the triple helix in discussing maritime issues.
O ENSINO DE CIÊNCIAS NATURAIS: Uma proposta de educação contextualizada para o Semiárido/Sertão
Authors: DE ALENCAR FIGUEIREDO GUSTAVO , GONZÁLEZ FREDT ENRIQUE , XAVIER MARIA KAMYLLA E SILVA 
Published: May 2021

Neste trabalho buscamos apresentar uma reflexão teórica tomando o desenvolvimento do Ensino de Ciências Naturais no Semiárido Brasileiro, tendo como perspectiva de subsidiar as práticas pedagógicas dos/as professores/as desse componente curricular no Ensino Fundamental, trazendo a importância do diálogo com os saberes historicamente construídos pelos povos que vivem nessa região, tendo em vista o significado da cultura popular da região Semiárida na formação de sujeitos críticos e autônomos. Procuramos, também, discutir sobre as políticas de formação de professores/as de Ciências e de desenvolvimento para o Semiárido Brasileiro tendo como fundamentação o que foi e está sendo feito para implementar uma proposta de educação, demonstrando como ela pode desconstruir o discurso que historicamente construiu subjetividades acerca do Semiárido no cenário nacional, negando suas verdadeiras potencialidades e os saberes compartilhados ao longo de toda sua existência pelos povos que vivem por toda sua extensão. O método adotado foi o de ensaio crítico-dialógico de conceitos a partir da literatura referente a temática relevantes para implementação de uma proposta de formação transdiciplinar para vivência no/do Semiárido/Sertão. A discussão sinaliza, para um olhar mais sensível frente à Lei nº 10.639/2003, que orienta o saber-fazer docente no que concerne uma educação para as relações étnico-raciais, bem como aponta possibilidades para enfrenter a descontextualização do currículo nas Ciências Naturais, o que impossibilita os/as estudantes refletirem sobre o verdadeiro papel da Ciência em suas vidas, para que eles/as possam entendê-la como parte de uma cultura produzida por homens e mulheres, bem como a sua relevância na compreensão dos fenômenos naturais observados no mundo que os/as cercam.
Geodynamics of the Wadati-Benioff zone earthquakes: The 2004 Sumatra earthquake and other great earthquakes
Authors: Scalera Giancarlo 
Published: May 2021

The displacement of the Earth’s instantaneous rotation pole – observed at ASI of Matera, Italy – the seismic data (USGS) in the two days following the main shock, the high frequency P-wave radiation, the geomorphologic data, and the satellite data of uplift/subsidence of the coasts (IGG) converge toward a new interpretation of the Great Sumatran earthquake (TU=26 December 2004 - 00h 58m, Lat=3.3°N, Lon=95.8°E, H=10 km, M=9.3) based on the second conjugate – nearly vertical – CMT fault plane solution. In a non-double-couple treatment that considers non-negligible non-elastic contributions to the earthquake phenomena, only a nearly vertical fault can explain both high values of seismic moment and the ?3.0 mas (?10 cm) polhody displacement toward an azimuth exactly opposite to the epicentre azimuth.
Case-histories of great earthquakes are then reviewed to highlight the overall analogies. The similarity of the vertical displacements shown by these earthquakes (Chile 1960, Alaska 1964, ...) leads to a common interpretation necessitating resort to a prevailing uprising of lithospheric material. This interpretation is supported by the inspection of the irregularities of the hypocentre distribution along the Wadati-Benioff zones. Moreover, in the case of great South American earthquakes, a volcanic eruptions-earthquakes correlation is clearly recognisable.
A thorough revision of the pure elastic rebound model of great earthquakes occurrence and a complete overcoming of the large scale subduction concept is then needed.
Bittersweet Food
Authors: Liao Shen-Yi 
Published: May 2021

Nostalgia and food are intertwined universals in human experience. All of us have experienced nostalgia centered on food, and all of us have experienced food infused with nostalgia. To explore the links between nostalgia and food, I start with a rough taxonomy of nostalgic foods, and illustrate it with examples. I argue that there is a psychological commonality to experiencing nostalgic foods: imagination. On my account, imagination is the key to understanding the cognitive, conative, affective, and perceptual aspects of experiencing nostalgic foods. In turn, the recognition of imagination’s centrality in experiencing nostalgic foods reveals how food can produce aesthetic experiences comparable to those produced by literature and painting.
Peningkatan Kesadaran Masyarakat tentang Pencegahan COVID-19 berbasis Keluarga dengan Memanfaatkan Motion Grafis di Jakarta Timur
Authors: Yatimah Durotul , Kustandi Cecep , Maulidina Azmira , Irnawan Fernanda , Andinnari Shaffiya Rasidha 
Published: May 2021

Kesadaran masyarakat terhadap masa pandemi ini sangatlah minim, banyak yang menganggap COVID-19 tidak terlalu menyeramkan. Survei yang dilakukan oleh LaporCOVID-19 di Provinsi DKI Jakarta menyatakan bahwa 26% responden percaya bahwa Indonesia aman dari pandemi corona karena beriklim tropis. Sebanyak 45% tidak percaya, dan sisanya 28% ragu. Terhitung 31 Juli 2020 ini, di DKI Jakarta kasus COVID-19 terkonfirmasi sebanyak 11.424 kasus dan 632 orang meninggal dunia. Dengan demikian perlu dilakukan upaya peningkatan kesadaran masyarakat tentang pencegahan penularan COVID-19 berbasis keluarga untuk membantu kesadaran masyarakat di Jakarta Timur. Target sasaran pengabdian adalah Kelurahan Pondok Bambu, Kecamatan Duren Sawit. Pengabdian pada masyarakat terintegrasi KKN ini menggunakan pendekatan dengan sebagai berikut: 1) tahap perencanaan; 2) tahap persiapan; 3) tahap pelaksanaan; 4) tahap evaluasi. Dari seluruh rangkaian kegiatan pelaksanaan pengabdian masyarakat ini telah disebarkan berbagai konten baik digital dan non digital. Kelurahan sasaran yakni Kelurahan Pondok Bambu, Jakarta Timur sudah dipasangkan banner yang berisikan perlunya kesadaran masyarakat mengenai virus COVID-19. Kemudian siap untuk menghadapi New Normal untuk para pengunjung kelurahan agar tetap waspada. Serta pemanfaatan konten motion graphic di YouTube dan flyer untuk Instagram Story oleh anggota tim pengabdian dilakukan untuk meningkatkan kesadaran masyarakat secara optimal terkait COVID-19
Pengembangan Sentra Industri UKM Krupuk Terasi Dalam Menghadapi Era New Normal: Studi Ukm Budi Jaya Makmur Di Desa Buden-Lamongan
Authors: Rosyad Sabilar , Priambodo Wisnu 
Published: May 2021

Usaha Kecil Menengah (UKM) mempunyai peran penting dan strategis bagi pertumbuhan ekonomi negara, baik negara berkembang maupun negara maju. Pada saat krisis ekonomi berlangsung di Indonesia, Usaha Kecil Menengah merupakan sektor ekonomi yang memiliki ketahanan paling baik. Kemampuan UKM perlu diberdayakan dan dikembangkan secara terus menerus dengan berusaha mereduksi kendala yang dialami UKM, sehingga mampu memberikan kontribusi lebih maksimal terhadap peningkatan kesejahteraan masyarakat. Penelitian ini menunjukkan bahwa penyebab menurunya penjualan adalah dampak dari pandemi Covid-19, kenaikan harga bahan baku, dan kurangnya inovasi produk. Oleh karena itu perlu adanya pembinaan dari pemerintah dalam mengembangkan inovasi produk dan inovasi dalam pemasaran. Sehingga eksistensi sentra industri kerupuk terasi dapat berkembang dan membuka lapangan pekerjaan bagi warga sekitar serta meningkatkan pendapatan asli warga desa buden..