bluuebunny/crossref_metadata_2025_split huggingface dataset:
MORPHOLOGICAL ASPECTS OF THE RELATIONSHIP BETWEEN PERIODONTAL TISSUES AND DENTAL PULP
Authors: Moiseev Denis , Rumyantsev Vitalij , Volkov Sergey , Kulyukina Maria , Konov Anton 
Published: August 2021

Researchers are currently paying more and more attention to the combined pathology of the tooth pulp and periodontal. At the same time, the peculiarities of the structure of the alveolar bone, the cement of the tooth root and the root canal system that cause their interrelation and mutual influence remain insufficiently studied. The main elements of the connection between the pulp and periodontal tissues are not only apical openings and additional channels, but also other ways of interaction, the study of which is of great interest for understanding the features of pathogenesis, prognosis and treatment of combined diseases of the tooth pulp and periodontal.
The aim of the study is to identify the topographical and anatomical features of the structure of the roots of teeth of different functional groups and the surfaces of their holes when studying on human cadaver material.
The hypothesis of the study is that the number of openings of the Haversov channels and their localization in the moons are due to the functional affiliation of the teeth and they have their own characteristics.
Material and methods. The study was conducted on jawbones with teeth obtained from embalmed corpses of adults of different genders and ages. After appropriate preparation, at the first stage, microscopy of the alveolar surfaces was performed, followed by morphometric analysis of the photos. At the second stage, scanning electron microscopy (SEM) of the surfaces of the roots of teeth previously extracted from the same wells of the jaws was performed.
Results and discussion. All the preparations were systematized according to the number and topography of the identified holes of the Haversov channels. Because of the assessment of morphometric indicators, the number of holes, the density of their location and the diameter were determined, depending on the functional affiliation of the teeth. The analysis of microphotographs obtained because of SEM allowed us to determine the structural features of the surfaces of the roots of the teeth.
Conclusions. The number, density and diameter of the holes of the Haversov channels are determined by the functional affiliation of the tooth. With the help of SEM, micro cracks and areas of root dentin exposure were found on the surfaces of the roots of the teeth for the first time, which can contribute to the translocation of pathogenic microbiota from the periodontal pocket to the pulp of the tooth and vice versa.
Racial and Ethnic Disparities in Maternal Mortality in the United States Using Enhanced Vital Records, 2016‒2017
Authors: MacDorman Marian F. , Thoma Marie , Declcerq Eugene , Howell Elizabeth A. 
Published: August 2021

Objectives. To better understand racial and ethnic disparities in US maternal mortality. Methods. We analyzed 2016–2017 vital statistics mortality data with cause-of-death literals (actual words written on the death certificate) added. We created a subset of confirmed maternal deaths that had pregnancy mentions in the cause-of-death literals. Primary cause of death was identified and recoded using cause-of-death literals. We examined racial and ethnic disparities both overall and by primary cause. Results. The maternal mortality rate for non-Hispanic Black women was 3.55 times that for non-Hispanic White women. Leading causes of maternal death for non-Hispanic Black women were eclampsia and preeclampsia and postpartum cardiomyopathy with rates 5 times those for non-Hispanic White women. Non-Hispanic Black maternal mortality rates from obstetric embolism and obstetric hemorrhage were 2.3 to 2.6 times those for non-Hispanic White women. Together, these 4 causes accounted for 59% of the non-Hispanic Black‒non-Hispanic White maternal mortality disparity. Conclusions. The prominence of cardiovascular-related conditions among the leading causes of confirmed maternal death, particularly for non-Hispanic Black women, necessitates increased vigilance for cardiovascular problems during the pregnant and postpartum period. Many of these deaths are preventable.
Finite Element Modeling And Parametric Optimization of Solidly Mounted Film Bulk Acoustic Resonator For Its Performance Enhancement
Authors: Johar Arun Kishor , Bhatt Jai Kumar , Sharma Gaurav Kumar , Kumar Tangudu Bharat , Varma Tarun , Periasamy C. , Agarwal Ajay , Boolchandani Dharmendar 
Published: August 2021

Abstract
This paper reports, the application of Taguchi Design of Experiments (DoE) and ANOVA (Analysis of Variance) for finding the optimal combinations and analysis of the effect of individual layer thickness on the performance of SMR sensor. The optimum combination of design parameters and its performance as a sensor have been predicted with DoE and validated through the finite element modeling (FEM) simulation. The optimization has been done to achieve enhancement in coupling coefficient of SMR sensor. The best optimized thickness of metal electrodes, piezoelectric, sensing, insulation low and high acoustic impedance layers have been found to be 0.2µm, 2µm, 0.68µm, 0.3µm, 1.028µm and 1.008µm, respectively. The results of the present study show that for the optimized dimension of SMR structure, simulated values of coupling coefficient (K2eff), Quality factor (Q) and figure of merit (FoM) are 0.075596 (or 7.5596%), 1171.6 and ≈ 88, respectively. Optimized structure performance has been compared with the existing SMR sensors and it is observed that proposed SMR exhibits performance enhancement in terms of FoM by ≈ 37 %.
Regional comparative analysis of factors that affect child-birth among women in Ghana after marriage.
Authors: Iddrisu Abdul-Karim , Adams Mustapha , Odametey Akuye-Shika , Mensah Nana Kofi , Kwotua Paul A. 
Published: August 2021

Abstract
Introduction: Infertility or difficulty related to conception and childbirth is still a global health concern including Ghana. Infertility or child-birth associated difficulties after marriage can lead to divorce. However, risk factors associated with child-birth difficulties are often difficult to detect by both the Gynaecologist and the couple involved. This makes proposing solutions to issues related to child-birth usually unsuccessful. Methods: This study seeks to identify risk factors associated with child-birth among married women in Ghana. This was achieved by using a logistic regression model for the dichotomous birth length (birth within 10 months or after 10 months in marriage) variable, adjusting for risk factors of birth length. The data used for the study were obtained from the 2014 Ghana Demographic and Health Survey, consisting of 5,004 complete cases. Statistical analyses were carried out using STATA version 14.1, best-fitting model selected from candidate models using their respective Akaike Information Criterion or Bayesian Information Criterion and the predictive power of such model determined using the Receiver Operating Characteristic curve. Results: Respondents with Akan ethnic background are less likely to deliver their first child after 10 months of marriage, wives who reported that beating is justified if she goes out without her husband's notice are more likely to give birth to their first child after 10 months of marriage, wives who reported that beating is justified when she burns food are less likely to give birth to their first child after 10 months of marriage. A unit increase in the age of respondent at first sex at first cohabitation decreases the likelihood of giving birth to the first child after 10 months in marriage. Rich and middle-class wives are more likely to give birth after 10 months in marriage. Discussion and Conclusions: For wives to conceive within 10 months of marriage, wives and husbands should or are encouraged to have frequent sex, any negative social behaviour or policies must be discouraged. Husbands should openly express their desire and love for their children since this increases the likelihood of wife’s desire to give birth. This leads to frequent sex, which then reduces conception time, and hence, child-birth within the shortest possible time.
Distinction of Consciousness Fields According to Taheri from Other Conventional Physical Fields: Evaluating the Magnetic Properties of Materials
Authors: Taheri Mohammad Ali , Payervand Firouz , Ahmadkhanlou Farzad , Torabi Sara , Semsarha Farid 
Published: August 2021

Abstract
Magnetization hysteresis loop provides important information about the magnetic properties of materials. In this study, by examining the magnetic properties of three paramagnetic and diamagnetic materials in the vicinity of the Consciousness Fields (three types 1,2 and 3), we have investigated the nature of the Consciousness Fields in comparison with magnetic field. The magnetic properties of the materials under the influence of three distinct Consciousness Fields have changed significantly. Furthermore, the Consciousness Field 1 of the present study (with originally named Consciousness Bond Field by Taheri) has changed the magnetic properties of materials toward their physically inherent state in standard laboratory conditions. Based on the conditions and the results of the present study, it can be concluded that the Consciousness Fields are inherently neither electric nor magnetite fields and have a completely different and distinct impact on materials and their properties.
Highly selective behaviour of colon adenoma after administration of EMR composition and its HCT116-based model.
Authors: Jakabčin Patrik , Kello Martin , Záň Jozef , Kolář Josef , Ulicny Jozef 
Published: August 2021

Abstract
When applying the improved composition of solution used during endoscopic mucosal resection (EMR), we have observed unexpectedly large and quantitatively significant differences in adenoma response vs. healthy tissue of surrounding GIT tract, namely the selective reaction enhancing the adenoma volume and differentiated colour. The in vitro experiments on model neoplasia cell line HCT116 suggest that the robust differences in the response of starving cells can be traced down principally to the tetrastarch digestion and enhanced metabolic rate of neoplastic cells. The neoplastic tissue grows into several intestine layers so that submucosal injection of iso-oncotic tetrastarch compound leads to degradation of starch and production of oncotic molecules in submucosa transported by facilitated transport into the neoplastic tissue. The colour distinction is due to concentration differences of the reporting dye between three separated compartments, further enhancing the utility of the contrasting mixture. The diffusion dynamics shall be tuneable by optimizing starch composition, improving desirable pharmacokinetics.
Comparative analysis of the SPL genes among four Ipomoea species and the evidence for a role of some IbSPLs in storage root development in sweet potato (Ipomoea batatas)
Authors: Sun Haoyun , Mei Jingzhao , Hou Wenqian , Zhang Yang , Xu Tao , Wu Shaoyuan , Zhang Lei 
Published: August 2021

Abstract
Background

As a major family of plant-specific transcription factors, SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) genes play crucial regulatory roles in plant growth, development, and stress tolerance. SPL transcription factor family has been widely studied in various plant species, however, there are no systematic studies on SPL genes in genus Ipomoea.
Results

In this study, a total of 29, 27, 26, 23 SPL genes were identified in Ipomoea batatas, Ipomoea trifida, Ipomoea triloba, and Ipomoea nil, respectively. Phylogenetic analysis indicated that Ipomoea SPL genes could be clustered into eight clades. SPL members within the same clade showed similar gene structures, domain organizations, and cis-acting element compositions, suggesting similarity of biological function potentially. Evolutionary analysis revealed that segmental duplication events played a major role in the Ipomoea genus-specific expansion of SPL genes. Of these Ipomoea SPL genes, 69 were predicted as the target genes of miR156, and 7 IbSPL genes were further confirmed by degradome data. Additionally, IbSPL genes showed diverse expression patterns in various tissues, implying their functional conservation and divergence. Finally, by combining the information from expression patterns and regulatory sub-networks, we found that four IbSPL genes (IbSPL16/IbSPL17/IbSPL21/IbSPL28) may be involved in the formation and development of storage roots.
Conclusions

This study not only provides novel insights into the evolutionary and functional divergence of the SPL genes in all available sequenced species in genus Ipomoea, but also lays a foundation for further elucidation of the potential functional roles of IbSPL genes during storage root development.
Anti-Diabetic Activity of Silver Nanoparticles Synthesized From The Hydroethanolic Extract of Myristica Fragrans Seeds
Authors: P Ramya , Krishnadhas Lavanya 
Published: August 2021

Abstract
Myristica fragrans, also known as nutmeg is a spice that cures various diseases. This study aimed to synthesize silver nanoparticles from a hydroethanolic extract of Myristica fragrans seeds (MFHE) and evaluate their anti-diabetic properties. To MFHE, AgNO3 solution was added and exposed to sunlight to produce silver nanoparticles from hydroethanolic seed extract of Myristica fragrans (MFHENP). The MFHENP was characterized by numerous techniques. UV-visible spectroscopy confirmed the formation of silver nanoparticles by the absorption peak at 430nm. Scanning electron microscopy (SEM) studies revealed the shape and size of the particles at the range of 50-60nm. Energy-dispersive X-ray spectroscopy (EDX) disclosed the presence of silver ions. X-ray diffraction spectrum confirmed the crystalline nature of silver nanoparticles by the peak at 39o. FTIR analysis revealed the functional groups present in MFHE as well as in MFHENP and Zeta potential analysis was found to be 14mV. Furthermore, in-vitro anti-diabetic activity was investigated. MFHENP showed significant efficiency against the inhibition of alpha-amylase and alpha-glucosidase enzymes and also MFHENP retarded the glucose transport across the membrane which is analyzed by glucose diffusion and glucose uptake assays. Acarbose is used as a standard for all these methods and MFHENP efficiency proves their therapeutic potential for the treatment of diabetes mellitus.
Advance Directives in Patients With Head and Neck Cancer - Status Quo and Factors Influencing Their Creation
Authors: Allner Moritz , Gostian Magdalena , Balk Matthias , Rupp Robin , Allner Clarissa , Mantsopoulos Konstantin , Ostgathe Christoph , Iro Heinrich , Hecht Markus , Gostian Antoniu-Oreste 
Published: August 2021

Abstract
Background: Advance Care Planning (ACP) including living wills (LWs) and durable powers of attorney for healthcare (DPAHCs) is a highly relevant topic aiming to increase patient autonomy and reduce medical overtreatment. Data from patients with head and neck cancer are not currently available. Methods: In this single center cross-sectional study, we evaluated patients during their regular follow-up consultations at Germany’s largest tertiary referral center for head and neck cancer, regarding the frequency, characteristics, and influencing factors for the creation of advance directives (ADs) using a validated questionnaire tailored to our cohort. The advance directives included living wills, durable powers of attorney for healthcare, and combined documents (CDs). Results: Four hundred and forty-six patients were surveyed from 07/01/2019 to 12/31/2019 (response rate=65.9%). The mean age was 62.4 years (SD 11.9), 26.9% were women (n=120). 46.4% of patients (n=207) reported having authored at least one advance directive. These documents included 16 durable powers of attorney for healthcare (3.6%), 75 living wills (16.8%), and 116 combined documents (26.0%). In multinominal regression analysis, older age (OR≤0.231, 95% CI 0.097-0.548; p<0.001), regular medication (OR=1.862, 95% CI 1.048-3.308; p=0.034), and the marital status (“married”: OR=2.395, 95% CI 1.074-5.337; p=0.033; and “permanent partnership”: OR=4.526, 95% CI 1.100-18.625; p=0.036) emerged as significant factors increasing the likelihood of having an advance directive. In contrast, the stage of disease, the therapeutic regimen, the ECOG status, and the time from initial diagnosis did not correlate with the presence of any type of advance directive. Conclusion: Less than half of head and neck cancer patients had created an advance directive. Older and comorbid patients who were married or in a permanent partnership had a higher likelihood of having an advance directive. This is the first study investigating the current situation in head and neck oncology and providing evidence to identify a patient population in need of appropriate support.
Calculation of the Fine Structure Constant derived from Principle Theory.
Authors: Geilhaupt Manfred 
Published: August 2021

Abstract
Recently we have presented in a paper that the combination of two Principle Theories, General Relativity (GR) and Thermodynamics (TD), is able to derive the restmass (m) of an electron which (surprisingly) depends on the Sommerfeld Fine Structure Constant (FSC). In this paper we present a completed calculation of the FSC number (1/α=137.035999024(9)) from a GR+TD point of view
Efficacy and Safety of Artificial Tears Containing Lipidure and Hypromellose for the Treatment of Moderate Dry Eye Disease in Contact Lens Wearers
Authors: Gagliano Caterina , Amato Roberta , Scollo Davide , Avitabile Alessandro , Foti Roberta , Petrillo Francesco , Longo Antonio 
Published: August 2021

Abstract
Purpose: Dry eye disease (DED) involves up to 50% of the global population. The present study compared efficacy, tolerability and safety of the novel Respilac artificial tears containing Lipidure and hypromellose (HPMC) to the widely used Nextal artificial tears, HPMC-based, for the treatment of moderate DED in contact lenses (CL) wearers.Methods: In a prospective, single-center, randomized investigation, 30 patients aged ≥18 years, diagnosed with moderate DED and wearing CL were randomly assigned to Respilac (n=15) or to Nextal group (n=15). Patients self-administrated one drop of Respilac or Nextal in both eyes 3-times daily for 21 days. Changes in endpoints (Visual Analogue Scale (VAS) score for ocular tolerability, Symptom Assessment iN Dry Eye (SANDE) score, Non-Invasive First Break-Up Time (NIF-BUT) results, Tear analysis value, Meibography results, CL tolerability results were investigated, comparing treatment groups and time-points evaluations. Adverse events (AEs) were also recorded and evaluated.Results: VAS scores decreased with time (p<0.001) in both groups showing no statistically significant difference among them (p=0.13). Improvements were also detected, from screening to end-of-treatment, by SANDE scores for severity and frequency (p<0.001) and by Tear analysis results (p<0.001) with no observed difference between Nextal and Respilac arm. NIF-BUT, Meibography and CL tolerability values showed to be non-significantly affected by treatment nor by time. No AEs were detected.Conclusion: According to the study results, Respilac showed to be effective, safe and well-tolerated for the treatment of moderate DED in CL wearers. Lipidure-based ophthalmic solution resulted not inferior to the currently used Nextal.
Risk of COVID-19 Introduction into the Scottish Hebrides and Strategies for Control
Authors: Ruget Anne-Sophie , Banks Christopher J. , Enright Jessica , Kao Rowland R. 
Published: August 2021

Abstract
Background In the context of an outbreak the natural boundaries of islands can allow for control of movements between populations. We estimate the risk of introduction of COVID-19 to each of the Hebridean islands situated off the west coast of mainland Scotland due to individual movements, and explore control strategies to mitigate this risk.Methods We use a combination of real human mobility data and census data to generate seasonally varying patterns of human movements amongst the Hebrides and from elsewhere. We consider three distinct periods: each of summer and winter 2019, illustrating a year prior to the pandemic, and summer 2020 illustrating a "pandemic summer". Movements during these periods serve as input to simulate COVID-19 transmission from the mainland to the archipelago in a stochastic meta-population model allowing us to explore the impact of seasonal variations on the risk of introduction and the effectiveness of non-pharmaceutical interventions.Results Despite strong seasonality in movement patterns, partly driven by tourism, for islands closely connected to the mainland there is evidence of substantial risk of disease introduction even over winter. In summer, when the risk is the highest, some islands can delay the introduction of COVID-19 by over six weeks, i.e. beyond the summer holiday period, through a 70% reduction of movements. Conclusion A high introduction risk in winter will be of particular concern if COVID-19 becomes a seasonal respiratory infection affecting temperate areas in winter concomitantly with other seasonal infections such as flu.For some islands, control of movements in peak summer tourist season has the potential for delaying the introduction risk beyond the summer holiday period, i.e. beyond a period of high mobility of people, potentially inducing a risk for rapid spread. Such measures would be particularly relevant in the occurrence of a variant escaping the vaccine given the current progress of the vaccine roll-out. However, such restrictions must be balanced against indirect negative economic impacts that might result.
Cancer-Related Fatigue On Daily Living Activities in Pediatric Cancer Survivors
Authors: Tanrıverdi Müberra , Çakır Fatma Betül 
Published: August 2021

Abstract
Aim

Cancer-related long term complications such as cardiovascular disease, fatigue, weight-related problems, and emotional disturbances are found to be increased in pediatric cancer survivors (PCS). The relationship between daily living activities (DLA) and such complications is still being investigated. Our aim in this study was to investigate the impact of cancer-related fatigue on DLA in PCS.
Methods

Cancer-related fatigue was assessed by “PedsQL Multidimensional Fatigue Scale (MFS)”, “Visuel Analogue Scale (VAS)” and “Borg Fatigue Scale”. The DLA was evaluated by WeeFIM.
Results

There were 77 PCS (44 boys) with a mean age of 10.76 ± 4.49 years. The mean value of fatigue scales were VAS 2.48 ± 1.48, Borg 0.61 ± 1.00 and MFS total score 71.14 ± 18.74. There was a statistically significant negative relationship between age and VAS scores of PCS (p = 0.047). The girls were found more tired than boys (VAS; p = 0.031). A positive correlation was established between the type of tumor and MFS total score (p = 0.048). WeeFIM total result was 118.64 ± 11.37. While there was a statisticially significant relationship between VAS Fatigue Score and WeeFIM total (p = 0.07), there was no such correlation between MFS total and WeeFIM total (p = 0.080) and Borg Fatigue Scale and WeeFIM total (p = 0.449).
Conclusions

It is established that there is a relationship between level of fatigue and DLA. Risk factors like tumor type or treatment modalities for fatigue should be investigated in larger samples of specific survivor groups. Fatigue and its association with DLA should be screened clinically as a routine surveillence in PCS and treatment options be planned.