bluuebunny/crossref_metadata_2025_split huggingface dataset:
The current status of daycase hip and knee arthroplasty within the English National Health Service: a retrospective analysis of hospital episode statistics data
Authors: Wainwright TW 
Published: March 2021

Introduction A high volume of total hip, total knee and unicompartmental knee arthroplasty procedures, an ageing population and continuing financial pressures within the English NHS mean that strategies to reduce length of hospital stay are attractive. Enhanced recovery after surgery protocols are one such intervention, and have advanced so that daycase arthroplasty is now possible. This study examines the current rate of daycase arthroplasty within the English NHS. Materials and Methods Hospital episode statistics data from all English NHS providers of arthroplasty procedures were analysed. Activity, daycase rate, length of stay and readmission rates were recorded. All total hip, knee and unicompartmental knee operations undertaken within the time period 1 July 2018 to 30 June 2019 were examined. Results Length of stay was analysed for 162,966 patients; 74,665 (46%) were total hip arthroplasty, 79,252 (49%) were total knee arthroplasty and 9,049 were unicompartmental knee arthroplasty (5%). Mean length of stay was 4.08 days for total hip, 4.11 days for total knee and 2.64 days for unicompartmental knee arthroplasties. Daycase rate for total hip arthroplasty was 0.55%, 0.52% for total knee arthroplasty and 5.44% for unicompartmental knee arthroplasty. The percentage of patients staying in hospital for longer than four days (a length of stay of five days or more) was 18.61% of total hip arthroplasty spells, 20.54% of total knee arthroplasty spells and 5.48% of unicompartmental knee arthroplasty spells. Discussion This large observational study of unselected patients undergoing hip and knee arthroplasty demonstrates that the national daycase rate for arthroplasty across providers in the NHS is low. Mean length of stay remains higher than selected international comparators.
Sarcopenia as a predictor of postoperative risk of complications, mortality and length of stay following gastrointestinal oncological surgery
Authors: Wang H , Yang R , Xu J , Fang K , Abdelrahim MEA , Chang L 
Published: March 2021

Introduction Sarcopenia has drawn considerable attention as a predictor of postoperative risk, although the relationship between sarcopenia and postoperative risk is contentious. This meta-analysis was conducted to evaluate this relationship. Methods A systematic literature search up to May 2020 was carried out and 43 studies were identified (with 16,716 patients) reporting on the relationship between sarcopenia and postoperative risk. In order to evaluate this relationship, odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using the dichotomous and continuous method with a random or fixed effects model. Results Compared with non-sarcopenic patients, those with sarcopenia have a higher major complications rate (OR: 4.03, 95% CI: 2.49–5.57, p<0.001), a higher total complications rate (OR: 1.77, 95% CI: 1.40–2.24, p<0.001), a higher 30-day mortality rate (OR: 2.38, 95% CI: 1.56–3.63, p<0.001) and a longer hospital stay (mean difference: 4.54 days, 95% CI: 2.49–6.59 days, p<0.001). Conclusions Sarcopenia significantly increases the risk of major complications, total complications, 30-day mortality and length of hospital stay. For this reason, it is recommended that sarcopenia is added to preoperative risk evaluation to avoid any possible negative outcomes following gastrointestinal oncological surgery.
Soil-transmitted helminth infection in pregnancy and long-term child neurocognitive and behavioral development: A prospective mother-child cohort in Benin
Authors: Garrison Amanda , Boivin Michael , Khoshnood Babak , Courtin David , Alao Jules , Mireku Michael , Ibikounle Moudachirou , Massougbodji Achille , Cot Michel , Bodeau-Livinec Florence 
Published: March 2021

Background
An estimated 30% of women in Sub-Saharan Africa suffer from soil-transmitted helminth infection during pregnancy (SHIP), which has been shown to increase risk of pre-term birth, low birth weight, and maternal anemia. A previous study in Benin found that SHIP was associated with impaired cognitive and gross motor development scores in 635 one-year-old children. The objective of the present study was to follow children prospectively to investigate whether the association between SHIP and child neurocognitive and behavioral development persisted at age six.

Principal findings
Our prospective child cohort included 487 live-born singletons of pregnant women enrolled in the Malaria in Pregnancy Preventive Alternative Drugs clinical trial in Allada, Benin. SHIP was assessed at three antenatal visits (ANVs) through collection and testing of stool samples. Neurocognitive and behavioral development was assessed in six-year-old children by trained investigators using the Kaufman Assessment Battery for Children 2nd edition and the parent-reported Strengths and Difficulties Questionnaire (SDQ). Multiple linear regression models generated coefficients and 95% confidence intervals and potential mediating factors were tested. Prevalence of SHIP was 13% at the 1st ANV, 9% at the 2nd ANV, and 1% at delivery. SHIP was not associated with low neurocognitive scores in children at six years. Higher SDQ internalizing scores, indicating increased emotional impairments in children, were associated with helminth infection at the 2nd ANV/delivery 1.07 (95% CI 0.15, 2.00) and at least once during pregnancy 0.79 (95% CI 0.12, 1.46) in adjusted models. Mediation analysis did not reveal significant indirect effects of several mediators on this association.

Conclusions
Our study shows that while SHIP is not associated with impaired long-term neurocognitive development, infections may have significant negative impacts on emotional development in six-year-old children. SHIP remains a critical public health issue, and adequate prevention and treatment protocols should be enforced in low- and middle-income countries.
Establishment of reference intervals of clinical chemistry analytes for the adult population in Egypt
Authors: Baz Heba , Ichihara Kiyoshi , Selim May , Awad Ahmed , Aglan Sarah , Ramadan Dalia , Hassab Amina , Mansour Lamia , Elgaddar Ola 
Published: March 2021

Background
This is the first Egyptian nationwide study for derivation of reference intervals (RIs) for 34 major chemistry analytes. It was conducted as a part of the global initiative by the IFCC Committee on Reference Intervals and Decision Limits (C-RIDL) for establishing country-specific RIs based on a harmonized protocol.

Methods
691 apparently healthy volunteers aged ≥18 years were recruited from multiple regions in Egypt. Serum specimens were analyzed in two centers. The harmonization and standardization of test results were achieved by measuring value-assigned serum panel provided by C-RIDL. The RIs were calculated by parametric method. Sources of variation of reference values (RVs) were evaluated by multiple regression analysis. The need for partitioning by sex, age, and region was judged primarily by standard deviation ratio (SDR).

Results
Gender-specific RIs were required for six analytes including total bilirubin (TBil), aspartate and alanine aminotransferase (AST, ALT). Seven analytes required age-partitioning including glucose and low-density lipoprotein cholesterol (LDL-C). Regional differences were observed between northern and southern Egypt for direct bilirubin, glucose, and high-density-lipoprotein cholesterol (HDL-C) with all their RVs lower in southern Egypt. Compared with other collaborating countries, the features of Egyptian RVs were lower HDL-C and TBil and higher TG and C-reactive protein. In addition, BMI showed weak association with most of nutritional markers. These features were shared with two other Middle Eastern countries: Saudi Arabia and Turkey.

Conclusion
The standardized RIs established by this study can be used as common Egyptian RI, except for a few analytes that showed regional differences. Despite high prevalence of obesity among Egyptians, their RVs of nutritional markers are less sensitive to increased BMI, compared to other collaborating countries.
Erectile dysfunction and its associated factors among the male population in Adigrat Town, Tigrai Region, Ethiopia: A cross-sectional study
Authors: Gebremedhin Haftom Tesfay , Mezgebo Hagos Mehari , Geberhiwot Gessessew Teklebrhan , Gebru Tesfay Tsegay , Tesfamichael Yowhans Ashebir , Ygzaw Hailu Belay , Baraki Mulu Ftwi , woledemariam Guesh Teklu , Gebru Tsegu Hailu , Tadese Haileslassie Tesfay , Kindeya Gebreslassie Gebreegziabhier , Azale Telake 
Published: March 2021

Background
Erectile dysfunction is one of the common sexual dysfunctions, but it is generally misunderstood as it is not a condition that threatens life. It affects an individual’s physical as well as psychosocial health and has a significant impact on sufferers and their families’ quality of life. No data are suggesting the prevalence of erectile dysfunction at the population level in Ethiopia. This research aimed to assess the prevalence and associated factors of erectile dysfunction among the male population.

Methods
We employed a community based cross-sectional study among 802 study participants. A two-stage random sampling method was used for enrolling study participants. Including the International Index of Erectile Function Questionnaire-5 (IIEF-5) for erectile dysfunction, data were collected using pretested and a structured questionnaire administered by an interviewer. Binary logistic regression was performed to identify factors associated with erectile dysfunction.

Result
Out of the total of 802 individuals, 25.4%(95% CI:(22.4, 28.3%)) (n = 204) reported erectile dysfunction. The mean age of the participants was 34.3 ± 9.6 years. Age of 40years and above [AOR = 10.74, 95% CI: (7.07, 16.35)], physical inactivity [AOR = 3.62, 95% CI: (2.40, 5.45)], depression [AOR = 4.01, 95% CI: (2.22, 7.21)], poor quality of life [AOR = 1.59, 95% CI: (1.07, 2.36)] were significantly associated with erectile dysfunction.

Conclusions
In this study, the prevalence of erectile dysfunction was high. Therefore, it is recommended that erectile dysfunction treatment be integrated into the health care system that focuses on educating and inspiring people on healthy eating, physical activity, and behavior enhancing wellbeing.
B cell and monocyte phenotyping: A quick asset to investigate the immune status in patients with IgA nephropathy
Authors: Sendic Senka , Mansouri Ladan , Lundberg Sigrid , Nopp Anna , Jacobson Stefan H. , Lundahl Joachim 
Published: March 2021

Background
IgA nephropathy (IgAN) advances from multiple pathogenic “hits” resulting in poorly O-galactosylated IgA1 glycoforms (Gd-IgA1), production of antibodies and glomerular deposition of immune complexes. A sequence of immune responses arising from plasma cells, T cells and antigen presenting cells (APCs), causes glomerular injury. This study was designed to phenotype subsets of B cells, monocytes and T cells in the peripheral circulation and their association with inflammatory cytokines and kidney function in patients with IgAN, healthy controls (HC) and disease controls with autosomal dominant polycystic kidney disease (ADPKD).

Methods
Patients with IgAN (n = 13), median estimated glomerular filtration rate (eGFR) of 57 ml/min/1.73m2 (IQR 42–84), patients with ADPKD (n = 13) matched for kidney function, gender and age and gender and age-matched HC (n = 13) were recruited. CD3+ and CD3- peripheral blood mononuclear cells were isolated and profiled based on their specific surface markers for different subsets of monocytes, B and T cells and analyzed by flow cytometry. Cytokines were analyzed by ELISA.

Results
We observed a significant decrease in the proportion of pre-switched B cells and plasmablasts, but an increase in long-lived plasma cells in the peripheral circulation of IgAN patients compared to HC. The proportion of non-classical monocytes was significantly higher in IgAN patients compared to both HC and ADPKD. We also report an association between sCD40L levels and the proportion of pre-switched B cells, as well as sCD40L and MCP-1 levels and albuminuria in IgAN patients.

Conclusions
We applied an easy-access method to analyze subsets of immune cells as well as relevant inflammatory mediators in IgAN patients. Our data demonstrate an altered B cell profile that indicates a pathophysiological role of the B cell lineage and an increased proportion of non-classical monocytes that suggests their role in the disease process.
Evidence-based practice utilization and associated factors among nurses working in Amhara Region Referral Hospitals, Ethiopia
Authors: Aynalem Zewdu Bishaw , Yazew Kassahun Gebeyehu , Gebrie Mignote Hailu 
Published: March 2021

Background
Applying evidence-based practice during care provision is essential because it improves the quality of care, reduces health care costs, and increases patient and family satisfaction. However, information on evidence-based nursing practice and associated factors were not well studied and documented in the study area. Hence, this study aimed to assess utilization and associated factors of evidence-based practice among nurses working in Amhara Region Referral Hospitals, Ethiopia.

Methods
An institution-based cross-sectional study was conducted from March 18 to April 16, 2019, in Amhara Region Referral Hospitals. A simple random sampling technique was used to select 684 respondents. Data were collected using a pretested and self-administered questionnaire. Data were entered into Epi Info version 7.1.2.0 and exported to SPSS version 22.0 for analysis. The bivariable analysis was used primarily and variables with p-value < 0.2 were further examined using a multivariable logistic regression model to control con-founders. Then, variables’ p-value < 0.05 with 95% CI was used to determine associated factors.

Results
From 684 proposed nurses, 671 of them completed the questionnaire giving 98.1% response rate. Of these, 55% (95% CI: 51.2, 58.9) of them had good evidence-based practice utilization. Variables including single (AOR = 1.662: 95% CI: 1.089–2.536), fewer work experience (AOR = 1.849: 95% CI: 1.049–3.257), good knowledge (AOR = 2.044: 95% CI: 1.406–2.972), effective communication skill (AOR = 2.537: 95% CI: 1.744–3.689), EBP training (AOR = 3.224 95% CI: 1.957–5.311), internet access (AOR = 1.655: 95% CI: 1.119–2.448) and evidence-based guideline availability (AOR = 1.827: 95% CI: 1.249–2.673) were found to be predictors of evidence-based practice utilization.

Conclusions
The study revealed that evidence-based practice utilization among nurses is low. Availing evidence-based guidelines in the work area, improving facilities’ internet access, and building nurses’ evidence-based practice competencies through either by giving separate training or incorporating as part of the curriculum would improve its utilization.
Association between sarcopenia level and metabolic syndrome
Authors: Kim Su Hwan , Jeong Ji Bong , Kang Jinwoo , Ahn Dong-Won , Kim Ji Won , Kim Byeong Gwan , Lee Kook Lae , Oh Sohee , Yoon Soon Ho , Park Sang Joon , Lee Doo Hee 
Published: March 2021

Aims
Metabolic syndrome (MetS) increases the risk of diabetes mellitus (DM), cardiovascular disease (CVD), cancer, and mortality. Sarcopenia has been reported as a risk factor for MetS, non-alcoholic fatty liver disease, and CVD. To date, the association between sarcopenia and MetS has been investigated. However, there have been few studies on the dose-response relationship between sarcopenia and MetS. We investigated the association between sarcopenia and the prevalence of MetS. We also aimed to analyze the dose-response relationship between skeletal muscle mass and the prevalence of MetS.

Methods
We enrolled 13,620 participants from October 2014 to December 2019. Skeletal muscle mass was measured using bioelectrical impedance analysis (BIA). Appendicular skeletal muscle mass (ASM) was divided by body weight (kg) and was expressed as a percentage (ASM x 100/Weight, ASM%). The quartiles of ASM% were calculated for each gender, with Q1 and Q4 being the lowest and highest quartiles of ASM%, respectively. The quartiles of ASM% were calculated for each gender, with Q1 and Q4 being the lowest and highest quartiles of ASM%, respectively. Linear regression and logistic regression analyses were used to compare the clinical parameters according to ASM%, adjusted for age, sex, obesity, hypertension (HT), DM, dyslipidemia (DL), smoking, alcohol intake, and C-reactive protein (CRP). Multiple logistic regression analysis was performed to determine the risk of MetS in each group.

Results
A dose-response relationship was identified between ASM% and MetS. Sarcopenia was associated with an increased prevalence of MetS. After adjustment for age, sex, obesity, HT, DM, DL, smoking, alcohol intake, and CRP, sarcopenia remained significantly associated with MetS. For each 1 quartile increment in ASM%, the risk of MetS decreased by 56% (P< 0.001). After adjusting for age, sex, obesity, HT, DM, DL, smoking, alcohol intake, and CRP, the risk of MetS decreased by 25% per 1Q increment in ASM% (P < 0.001).

Conclusions
Sarcopenia by BIA is independently associated with the risk of MetS and has a dose-response relationship.
Patterns and associated factors of diabetes self-management: Results of a latent class analysis in a German population-based study
Authors: Heise Marcus , Fink Astrid , Baumert Jens , Heidemann Christin , Du Yong , Frese Thomas , Carmienke Solveig 
Published: March 2021

Objective
Few studies on diabetes self-management considered the patterns and relationships of different self-management behaviours (SMB). The aims of the present study are 1) to identify patterns of SMB among persons with diabetes, 2) to identify sociodemographic and disease-related predictors of SMB among persons with diabetes.

Research design and methods
The present analysis includes data of 1,466 persons (age 18 to 99 years; 44.0% female; 56.0% male) with diabetes (type I and II) from the population-based study German Health Update 2014/2015 (GEDA 2014/2015-EHIS). We used latent class analysis in order to distinguish different patterns of self-management behaviours among persons with diabetes. The assessment of SMB was based on seven self-reported activities by respondents (dietary plan, diabetes-diary, diabetes health pass, self-assessment of blood glucose, self-examination of feet, retinopathy-screenings and assessment of HbA1c). Subsequent multinomial latent variable regressions identified factors that were associated with self-management behaviour.

Results
Latent class analysis suggested a distinction between three patterns of SMB. Based on modal posterior probabilities 42.8% of respondents showed an adherent pattern of diabetes self-management with above-average frequency in all seven indicators of SMB. 32.1% showed a nonadherent pattern with a below-average commitment in all seven forms of SMB. Another 25.1% were assigned to an ambivalent type, which showed to be adherent with regard to retinopathy screenings, foot examinations, and the assessment of HbA1c, yet nonadherent with regard to all other forms of SMB. In multivariable regression analyses, participation in Diabetes Self-Management Education programs (DSME) was the most important predictor of good self-management behaviour (marginal effect = 51.7 percentage points), followed by attentiveness towards one’s personal health (31.0 percentage points). Respondents with a duration of illness of less than 10 years (19.5 percentage points), employed respondents (7.5 percentage points), as well as respondents with a high socioeconomic status (24.7 percentage points) were more likely to show suboptimal forms of diabetes self-management.

Discussion
In the present nationwide population-based study, a large proportion of persons with diabetes showed suboptimal self-management behaviour. Participation in a DSME program was the strongest predictor of good self-management. Results underline the need for continual and consistent health education for patients with diabetes.
Dissipative Heating in a Rotational Viscometer with Coaxial Cylinders
Authors: Rieger F. 
Published: March 2021

Rotational viscometers with coaxial cylinders are often used for measuring rheological behaviour. If the inner to outer cylinder diameter ratio does not differ significantly from 1, the curvature can be neglected and the flow reduces to the flow between moving and stationary plates. The power-law and Bingham models are often used for describing rheological behaviour. This paper deals with the temperature distribution obtained by solving the Fourier-Kirchhoff equation and in the case of negligible inner heat resistance it also covers temperature time dependence. The solution is illustrated by a numerical example.
Influence of Different Speech Representations and HMM Training Strategies on ASR Performance
Authors: Bořil H. , Fousek P. 
Published: March 2021

This work studies the influence of various speech signal representations and speaking styles on the performance of automatic speech recognition (ASR). The efficiency of two approaches to hidden Markov model (HMM) training are compared.Common MFCC and PLP features were exposed to two sources of disturbance applied to the original wide-band speech: (i) stress (Lombard effect) and (ii) transfer channel distortion (simulated telephone line). Subsequently, the efficiencies of the two training strategies were evaluated. Finally, a study of the optimal number of training iterations is introduced.
Fuzzy Algorithm for Supervisory Voltage/Frequency Control of a Self Excited Induction Generator
Authors: Soliman Hussein F. , Attia Abdel-Fattah , Mokhymar S. M. , Badr M. A. L. 
Published: March 2021

This paper presents the application of a Fuzzy Logic Controller (FLC) to regulate the voltage of a Self Excited Induction Generator (SEIG) driven by Wind Energy Conversion Schemes (WECS). The proposed FLC is used to tune the integral gain (KI) of a Proportional plus Integral (PI) controller. Two types of controls, for the generator and for the wind turbine, using a FLC algorithm, are introduced in this paper. The voltage control is performed to adapt the terminal voltage via self excitation. The frequency control is conducted to adjust the stator frequency through tuning the pitch angle of the WECS blades. Both controllers utilize the Fuzzy technique to enhance the overall dynamic performance. The simulation result depicts a better dynamic response for the system under study during the starting period, and the load variation. The percentage overshoot, rising time and oscillation are better with the fuzzy controller than with the PI controller type.
Structure of the Enveloping Algebras
Authors: Burdík Č. , Navrátil O. , Pošta S. 
Published: March 2021

The adjoint representations of several small dimensional Lie algebras on their universal enveloping algebras are explicitly decomposed. It is shown that commutants of raising operators are generated as polynomials in several basic elements. The explicit form of these elements is given and the general method for obtaining these elements is described.