bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simultaneous cardio-cerebral infarction: a meta-analysis
Authors: Ng T P , Wong C , Leong E L E , Tan B Y , Chan M Y -Y , Yeo L L , Yeo T -C , Wong R C , Leow A S , Ho J S -Y , Sia C -H 
Published: May 2021

Summary

Background/Introduction
Cardio-cerebral infarction (CCI), which involves the simultaneous occurrence of acute ischaemic stroke and acute myocardial infarction, has a reported incidence of 0.0009%. Treatment of CCI presents a dilemma to physicians as both conditions are time critical. Despite the need for standardized treatment protocols, published data are sparse.

Aim
We aimed to summarize the reported cardio-cerebral infarction cases in the literature.

Design
Meta-analysis.

Methods
Four databases, Pubmed, Embase, Scopus and Google Scholar were searched until 25 August 2020. A title and abstract sieve, full-text review and extraction of data were conducted independently by three authors.

Results
A total of 44 cases of CCI were identified from 37 case reports and series; 15 patients (34.1%) were treated using percutaneous coronary intervention (PCI) with stent, 8 patients (18.2%) were treated with a PCI without stent, 10 patients (22.7%) were treated via a cerebral vessel thrombectomy and 8 patients (18.2%) were treated via a thrombectomy of a coronary vessel. For medications, 20 patients (45.5%) were treated with thrombolytics, 10 patients (22.7%) were treated with anticoagulants, 8 patients (18.2%) were treated with antiplatelets and 11 patients (25.0%) were treated with anticoagulants and antiplatelets. Of 44 patients, 10 patients died, and 9 of those were due to cardiac causes. Among the 44 patients, days to death was observed to be a median of 2.0 days (interquartile range (IQR): 1.5, 4.0). The modified Rankin Score was measured in nine patients, with a median score of 2.0 (IQR: 1.0, 2.5) being reported.

Discussion/Conclusion
The condition of CCI has substantial morbidity and mortality, and further studies are needed to examine the optimal diagnostic and treatment strategies of these patients.
Slippery when wet: cross-species transmission of divergent coronaviruses in bony and jawless fish and the evolutionary history of the Coronaviridae
Authors: Miller Allison K , Mifsud Jonathon C O , Costa Vincenzo A , Grimwood Rebecca M , Kitson Jane , Baker Cindy , Brosnahan Cara L , Pande Anjali , Holmes Edward C , Gemmell Neil J , Geoghegan Jemma L 
Published: May 2021

Abstract
The Nidovirales comprise a genetically diverse group of positive-sense single-stranded RNA virus families that infect a range of invertebrate and vertebrate hosts. Recent metagenomic studies have identified nido-like virus sequences, particularly those related to the Coronaviridae, in a range of aquatic hosts including fish, amphibians, and reptiles. We sought to identify additional members of the Coronaviridae in both bony and jawless fish through a combination of total RNA sequencing (meta-transcriptomics) and data mining of published RNA sequencing data and from this reveal more of the long-term patterns and processes of coronavirus evolution. Accordingly, we identified a number of divergent viruses that fell within the Letovirinae subfamily of the Coronaviridae, including those in a jawless fish—the pouched lamprey. By mining fish transcriptome data, we identified additional virus transcripts matching these viruses in bony fish from both marine and freshwater environments. These new viruses retained sequence conservation in the RNA-dependant RNA polymerase across the Coronaviridae but formed a distinct and diverse phylogenetic group. Although there are broad-scale topological similarities between the phylogenies of the major groups of coronaviruses and their vertebrate hosts, the evolutionary relationship of viruses within the Letovirinae does not mirror that of their hosts. For example, the coronavirus found in the pouched lamprey fell within the phylogenetic diversity of bony fish letoviruses, indicative of past host switching events. Hence, despite possessing a phylogenetic history that likely spans the entire history of the vertebrates, coronavirus evolution has been characterised by relatively frequent cross-species transmission, particularly in hosts that reside in aquatic habitats.
A Scoping Review of Quality of Life Questionnaires in Glaucoma Patients
Authors: Gazzard Gus , Kolko Miriam , Iester Michele , Crabb David P. 
Published: May 2021

Precis:
Multiple questionnaires exist to measure glaucoma’s impact on quality of life (QoL). Selecting the right questionnaire for the research question is essential, as is patients’ acceptability of the questionnaire to enable collection of relevant patient-reported outcomes.

Purpose:
QoL relating to a disease and its treatment is an important dimension to capture. This scoping review sought to identify the questionnaires most appropriate for capturing the impact of glaucoma on QoL.

Methods:
A literature search of QoL questionnaires used in glaucoma, including patient-reported outcomes measures, was conducted and the identified questionnaires were analyzed using a developed quality criteria assessment.

Results:
Forty-one QoL questionnaires were found which were analyzed with the detailed quality criteria assessment leading to a summary score. This identified the top 10 scoring QoL questionnaires rated by a synthesis of the quality criteria grid, considering aspects such as reliability and reproducibility, and the authors’ expert clinical opinion. The results were ratified in consultation with an international panel of ophthalmologists (N=49) from the Educational Club of Ocular Surface and Glaucoma representing 23 countries.

Conclusions:
Wide variability among questionnaires used to determine vision related QoL in glaucoma and in the responses elicited was identified. In conclusion, no single existing QoL questionnaire design is suitable for all purposes in glaucoma research, rather we have identified the top 10 from which the questionnaire most appropriate to the study objective may be selected. Development of a new questionnaire that could better distinguish between treatments in terms of vision and treatment-related QoL would be useful that includes the patient perspective of treatment effects as well as meeting requirements of regulatory and health authorities. Future work could involve development of a formal weighting system with which to comprehensively assess the quality of QoL questionnaires used in glaucoma.
Slow Coagulation Transscleral Cyclophotocoagulation for Postvitrectomy Patients With Silicone Oil–induced Glaucoma
Authors: Khodeiry Mohamed M. , Liu Xiangxiang , Sheheitli Huda , Sayed Mohamed S. , Lee Richard K. 
Published: May 2021

Precis:
Slow coagulation transscleral cyclophotocoagulation (TSCPC) is an effective and safe glaucoma surgery in patients with medically uncontrolled silicone oil (SO)-induced glaucoma.

Purpose:
The purpose of this study was to report the outcomes of slow coagulation continuous wave TSCPC in patients with medically uncontrolled secondary glaucoma following pars plana vitrectomy (PPV) and intravitreal SO injection.

Patients and Methods:
This retrospective study enrolled patients with medically uncontrolled glaucoma secondary to PPV with SO injection who underwent TSCPC using slow coagulation TSCPC settings (power of 1250 mW and duration of 4 s). The primary outcome measure was surgical success at 12 months. Surgical success was defined as an intraocular pressure 6 to 21 mm Hg and reduced ≥20% from baseline, no reoperation for glaucoma, and no loss of light perception vision. Secondary outcome measures included number of glaucoma medications, visual acuity changes, and surgical complications.

Results:
A total of 18 eyes of 18 patients were included in the study. The mean age and follow-up of the patients were 51.94±14.5 years and 16.3±3.5 months, respectively. The mean intraocular pressure decreased from 29.7±9.6 mm Hg preoperatively to 14.6±6.5 mm Hg at 12 months postoperatively (P<0.001). Glaucoma medications were reduced from 4.2±0.9 at baseline to 1.9±1.3 at 12 months after TSCPC (P<0.001). A nonsignificant change of logarithm of the minimum angle of resolution visual acuity was observed at 12 months (P=0.722). The success rate at 12 months was 72.2%. No major complications were reported during the first year of follow-up.

Conclusion:
Slow coagulation TSCPC had high efficacy and minimal complications when used as an initial glaucoma surgical procedure in patients with SO-induced glaucoma.
The Mediating Role of Spirituality on Depression, Alcohol Use Disorder, and Problem Gambling Among Korean College Students
Authors: Lee Young-Me , Hyun Mi Yeul , Choi Suyoung , Aquino Elizabeth 
Published: May 2021

Abstract
Excessive alcohol use and gambling problems among Korean college students in Korea have been recognized as significant public health issues. The purpose of this study was to identify the direct, indirect, and total influence of depression on alcohol use disorder and problem gambling to determine relative magnitudes of the specific mediating effects of spirituality. A cross-sectional correlational survey was conducted in South Korea with 239 college students. Study variables included the Center for Epidemiological Studies Depression Scale, a Spirituality Scale for Koreans, the Alcohol Consumption Questions, and the Korean version of the Canadian Problem Gambling Severity Index. Multiple-mediation analyses were performed. The results found that depression has a negative effect on each of the six subgroups of spirituality. In terms of the effects of spirituality on alcohol use disorder and problem gambling, spirituality was found to have a positive effect only on alcohol use disorder. The relationship between depression and those two addictive behaviors was significantly mediated by spirituality. Bootstrapping revealed that transcendence and connectedness were significantly mediating the relationship between depression and alcohol use disorder. For problem gambling, compassion and connectedness were found to be mediators affecting the relationship between depression and problem gambling. The finding suggests that spirituality's subscales affect two specific addiction problems in different ways. College students' excessive drinking and problem gambling can be prevented by developing and applying an intervention program that strengthens the connectedness of spirituality's subscales.
Frequency of Binge Drinking and Perception of Peer Alcohol Use
Authors: Lee Michael Jonas , Schick-Makaroff Kara , Kunyk Diane 
Published: May 2021

Abstract

Objectives
College and university student binge drinking is a critical health issue, and studies demonstrate students perceive high rates of drinking among their peers. High alcohol consumption and binge drinking are normalized throughout college and university, and there are gross misperceptions of perceived alcohol use among peers. The purpose of our study was to examine differences in perceptions of peer alcohol use after grouping students based on their frequency of binge drinking over a 2-week period.

Methods
A one-way analysis of variance test was used to compare the differences in the perception of peer alcohol use after grouping students by their frequency of binge drinking.

Results
Students who binge drink have significantly higher perceptions of peer alcohol use than their non-binge-drinking and abstaining peers.

Conclusions
These findings provide direction toward the feasibility of using perceptions of peer alcohol use to identify at-risk students to curtail dangerous drinking behavior.
Ayahuasca
Authors: Goldin Deana , Salani Deborah 
Published: May 2021

Abstract
Ayahuasca is a pan-Amazonian botanical hallucinogenic decoction made from a mixture of the bark of the Banisteriopsis caapi plant, containing a monoamine oxidase inhibitor, and Psychotria viridis (Rubiaceae) or Diplopterys cabrerana shrubs containing a serotonergic 2A receptor agonist, N,N-dimethyltryptamine, a powerful psychoactive substance. Ayahuasca is a traditional psychoactive sacrament that has been used for shamanic ceremonies for centuries. Ayahuasca is acclaimed for spiritual and psychotherapeutic benefits and is gaining popularity in the United States. Potential risks involved with usage of this hallucinogenic drug include psychotic episodes related to N,N-dimethyltryptamine and serotonin syndrome, which can be potentially life threatening. The consequences of ayahuasca use remain uncertain because of poor quality control, unpredictability, and polydrug interactions. Nurses, advanced practice nurses, and other healthcare providers working in outpatient settings, hospitals, and treatment centers need to be familiar with the pharmacology, possible drug interactions, and management for ayahuasca ingestion for optimal decision making. Nurses are well positioned to facilitate understanding and to advise and educate the public about the potential risks associated with ayahuasca ingestion.
Coronavirus Disease 2019 Exposure in Surgeons and Anesthesiologists at a New York City Specialty Hospital
Authors: Soffin Ellen M. , Reisener Marie-Jacqueline , Padgett Douglas E. , Kelly Bryan T. , Sama Andrew A. , Zhu Jiaqi , Salzmann Stephan N. , Chiapparelli Erika , Okano Ichiro , Oezel Lisa , Miller Andy O. , Cammisa Frank P. , Girardi Federico P. , Hughes Alexander P. 
Published: May 2021

Objective:
We measured the seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) immunoglobulin G (IgG) antibodies among surgeons and anesthesiologists and associated antibody status with coronavirus disease 2019 (COVID-19) clinical illness.

Methods:
A cross-sectional study of SARS-CoV-2 IgG seroprevalence with a survey assessing demographics, SARS-CoV-2 exposure risk, and COVID-19 illness. The primary outcome was the period prevalence of SARS-CoV-2 IgG antibodies associated with COVID-19 illness.

Results:
One hundred forty three surgeons and anesthesiologists completed both serology and survey testing. We found no significant relationships between antibody status and clinical role (anesthesiologist, surgeon), mode of commuting to work, other practice settings, or place of residence. SARS-CoV-2 IgG seroprevalence was 9.8%. Positive IgG status was highly correlated with presence of symptoms of COVID-19 illness.

Conclusions:
These results suggest the relative safety of surgeons and anesthesiologists where personal protective equipment (PPE) is available and infection control protocols are implemented.
Pheromone Receptors Help Cnaphalocrocis medinalis Avoid Competition in Rice Fields
Authors: Cheng Jianjun , Zhang Yongle , Du Yongjun 
Published: May 2021

AbstractCnaphalocrocis medinalis (Guene’e) (Lepidoptera: Pyralidae) is one of the most important insect pests that attack the rice crop, Oryza sativa L., in China, feeding on rice leaves. Chilo suppressalis and Sesamia inferens are two common insects living within the same ecological system that feed on rice stalks. Their behavior could affect C. medinalis’s choice of oviposition place, so we tested the electroantennogram (EAG) response of C. medinalis to a conspecific sex pheromone (Z11-18:OH; Z11-18:Ald; Z13-18:OH; Z13-18:Ald) and two other insects’ pheromone compounds (Z9-16:Ald; Z11-16Ald; Z11-16:OH;Z11-16:Ac and 16:Ald). The results indicate C. medinalis can detect those pheromones and is sensitive to Z11-16:Ald and Z9-16:Ald. In the heterologous expression system of Xenopus oocytes, we cloned three pheromone receptor genes, CmedPR1, CmedPR2, and CmedPR3. These had the same electroantennogram response, in addition to the response to the conspecific pheromone. CmedPR2 and CmedPR3 displayed strong sensitivity to Z11-16Ald and Z9-16:Ald. These results may contribute to clarifying how C. medinalis recognizes pheromones and interspecies communication.
Junior enterprise and entrepreneurial behavior in Brazil
Authors: Moraes Gustavo Hermínio Salati Marcondes de , Iizuka Edson Sadao , Rocha Anne Kathleen Lopes da , Diaféria Amanda Mecchi 
Published: May 2021

PurposeThe purpose of this paper is to analyze what is the influence of the junior enterprise environment on the entrepreneurial profile and intention of university students and what is the difference in the entrepreneurial behavior between students who participated and students who did not participate in junior enterprises.Design/methodology/approachA quantitative approach based on multivariate data analysis using confirmatory factor analysis and structural equation modeling was applied to a sample of 549 respondents.FindingsParticipation in junior enterprises influences the development of the students’ entrepreneurial profile more than their entrepreneurial intention. This study presents which behavioral characteristics are mostly developed with participation in a junior enterprise.Research limitations/implicationsThe questionnaire with perception conditions and self-assessment indicators; data collection by a single cross-sectional research design; the scope of the research, which did not use a probabilistic sampling.Practical implicationsPractical implications are to assist higher education institutions in having a more accurate understanding of the role of junior enterprises in stimulating university entrepreneurship. To implement an effective entrepreneurial education, stimulating junior companies can be a fundamental action for the HEIs, and this is valid for courses in all areas. Entrepreneurial education in a practical context, as in the case of a junior company, can increase entrepreneurial intention.Originality/valueThis research fills a research gap on the uncertainty of the effectiveness of entrepreneurial education in developing the entrepreneurial behavior and entrepreneurial intention of students, at least when considering the junior company as part of entrepreneurial education in the university context, presenting a robust quantitative methodology and a large sample in a developing country.
Explaining the directionality of gang violence with court records
Authors: Bichler Gisela , Norris Alexis , Ibarra Citlalik 
Published: May 2021

Purpose
Studies of gang violence typically use police reports to investigate the structure of gang conflict, but overreliance on a singular data source could impede crime control efforts. Extending networked criminology, this study aims to explore what court records reveal about the directionality of gang conflicts.

Design/methodology/approach
Controlling for the presence of a civil gang injunction (CGI), the authors use multivariate quadratic assignment procedure regression models to disentangle factors thought to account for structural patterns of gang violence mapped from 933 prosecutions involving 307 gangs associated with violent conflict affecting the City of Los Angeles (1998–2013). Specifically, the authors compare competitive advantage to the explanatory power of turf proximity.

Findings
One measure of turf proximity outperforms all other explanatory factors – gangs with turf centrally positioned in a turf adjacency matrix are significantly more likely to launch attacks, be victimized and exhibit the highest levels of imbalance in their violent involvements. Regarding competitive advantage, the number of cliques and level of internal conflict are significant. Finally, being subject to a CGI is associated with initiating violence.

Originality/value
Court cases offer a feasible alternative to police data when investigating patterns of intergroup street gang violence.
Using biopolymers to strengthen the historical printed paper: mechanical and optical characters
Authors: Noshy Wafika , Ali Hassan Rushdya Rabee , Mohammed Nada 
Published: May 2021

Purpose
This study aims to restore the lost mechanical properties of the prints with carrageenan, methyl hydroxyethyl cellulose (Tylose) and hydroxypropyl methylcellulose (Methocel).

Design/methodology/approach
The effect of these materials on the properties of the printed paper (modern and historical samples) has been evaluated under the influence of accelerated aging using pH measurement, the mechanical properties (tensile and elongation), FTIR and color changes.

Findings
The three consolidates reduced the acidity of treated samples significantly, but after ageing, it was observed that the pH of aged treated samples decreased slightly as compared to the untreated samples. The results of the mechanical properties showed the superiority of hydroxypropyl methylcellulose (Methocel) in improving the tensile and elongation forces of the samples compared to carrageenan and methyl hydroxyethyl cellulose even during the accelerated aging. Consolidation materials succeeded in reducing ΔE of the paper samples under accelerated aging, especially carrageenan. The IR spectra confirmed that no dramatic difference was observed in topically function vibrations of samples after treatment beside that the O-H stretching band intensity increased observably after treatment with the three consolidates, after ageing the treatment, and it protected the treated paper from oxidation processes as the infrared spectrum analysis showed a decrease in intensities of carbonyl and carboxyl groups as compared to aged untreated samples.

Originality/value
The research provides new biopolymers in strengthening the historical printed paper, where printed papers lack studies related to their conservation. This makes the current study a promising step for treating historical printed paper.
Early identification and intervention with individuals at risk of becoming involved in serious and organised crime (SOC)
Authors: Hurley Mick , Boulton Laura Jane 
Published: May 2021

Purpose
This paper aims to examine the “engage” pilot project and related processes for identifying individuals vulnerable to becoming involved in serious and organised crime groups (OCGs).

Design/methodology/approach
In this, a six-stage process developed in the five pilot sites to guide interventions is described. The project identified 18 individuals who have confirmed low level involvement in OCGs based in 5 areas of Greater Manchester by combining risk factors and the connecting of records held by law enforcement agencies.

Findings
Key risk factors found to be associated with the 18 individuals identified are described in relation to literature and discussed in terms of future intervention possibilities. A brief description of the key findings of the evaluation of the pilot project is also included.

Originality/value
Together these findings are discussed to explore the challenges of preventative interventions tailored towards young people already involved in criminality and offers recommendations for future programmes in this field.