bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of personal letters to healthcare professionals in changing professional behaviours: a systematic review protocol
Authors: Grimani Aikaterini , Goffe Louis , Tang Mei Yee , Beyer Fiona , Sniehotta Falko F. , Vlaev Ivo 
Published: April 2021

Abstract
Background
Letters are regularly sent by healthcare organisations to healthcare professionals to encourage them to take action, change practice or implement guidance. However, whether letters are an effective tool in delivering a change in healthcare professional behaviour is currently uncertain. In addition, there are currently no evidence-based guidelines to support health providers and authorities with advice on how to formulate the communication, what information and behaviour change techniques to include in order to optimise the potential effect on the behaviour of the receivers. To address this research gap, we seek to inform such guidance through this systematic review, which aims to provide comprehensive evidence of the effectiveness of personal letters to healthcare professionals in changing their professional behaviours.

Methods/design
A comprehensive literature search of published and unpublished studies (the grey literature) in electronic databases will be conducted to identify randomised controlled trials (RCTs) that meet our inclusion criteria. We will include RCTs evaluating the effectiveness of personal letters to healthcare professionals in changing professional behaviours. The primary outcome will be behavioural change. The search will be conducted in five electronic databases (from their inception onwards): MEDLINE, Embase, PsycINFO, the Cochrane Library and CINAHL. We will also conduct supplementary searches in Google Scholar, hand search relevant journals, and conduct backward and forward citation searching for included studies and relevant reviews. A systematic approach to searching, screening, reviewing and data extraction will be applied in accordance with the process recommended by the Cochrane Collaboration. Two researchers will examine titles, abstracts, full-texts for eligibility independently. Risk of bias will be assessed using the Cochrane Risk of Bias 2 (RoB 2) tool for randomised controlled trials. Disagreements will be resolved by a consensus procedure.

Discussion
Health policy makers across government are expected to benefit from being able to increase compliance in clinical settings by applying theories of behaviour to design of policy communications. The synthesised findings will be disseminated through peer-reviewed publication.

Systematic review registration
PROSPERO CRD42020167674
Physics webpages create barriers to participation for people with disabilities: five common web accessibility errors and possible solutions
Authors: Scanlon Erin , Taylor Zachary W. , Raible John , Bates Jacob , Chini Jacquelyn J. 
Published: April 2021

AbstractBackgroundWhile there have been numerous calls to increase the participation of people with disabilities in STEM, many postsecondary institutions are not equipped to support students with disabilities. We examined the accessibility of 139 webpages from 73 postsecondary institutions in the USA that contained information about the undergraduate physics curriculum and graduate research programs. We selected these webpages as they are common entry points for students interested in pursuing a physics degree. We used Tenon and Mac OS X’s VoiceOver software to assess the level of accessibility of these webpages as measured by alignment with the Web Content Accessibility Guidelines (WCAG) 2.0.ResultsWe found that only one webpage had minimal accessibility errors (i.e., 10 errors), while the other webpages had numerous accessibility errors. Five specific error types accounted for the majority of all errors. The five most common errors were related to information, structure, and relationships of content (1.3.1 Level A; 39.7%); text alternatives for non-text content (1.1.1 Level A; 27.0%); information about link purpose (2.4.4 Level A; 14.7%); capability to resize text (1.4.4 Level AA; 10.0%); and information about the name, role, and value of user interface components (4.1.2 Level A; 11.2%).ConclusionsWe present and describe the five common accessibility errors we identified in the webpages in our sample, suggest solutions for these errors, and provide implications for students with disabilities, instructors and staff, institutional administration, and the broader physics community.
The influence of kinesio taping on trunk and lower extremity motions during different landing tasks: implications for anterior cruciate ligament injury
Authors: Sheikhi Bahram , Letafatkar Amir , Hogg Jennifer , Naseri-Mobaraki Esmaiel 
Published: April 2021

Abstract
Purpose
The purpose of the study was to investigate the influence of a 72-h KT application on trunk and lower extremity kinematics during different landing tasks.

Methods
Twenty-nine competitive male athletes participated in this study. The sum of knee valgus and lateral trunk lean, symmetry index (SI), and peak angles of lateral trunk lean, hip flexion, knee abduction and flexion were assessed for all participants during single-leg drop landing (SLDL), single-leg vertical drop jump (SLVDJ), vertical drop jump (DLVDJ), and double leg forward jump (DLFJ), at baseline and seventy-two hours following KT application.

Results
The KT application resulted in more knee flexion and abduction, sum of knee valgus and lateral trunk lean as compared with the non-KT condition during SLDL (P < 0.05). Nonetheless, there were no differences in SI, maximum angle of the lateral trunk lean during SLDL, SLVDJ, nor hip flexion, knee abduction, and flexion during DLVDJ, and DLFJ tasks (P > 0.05).

Conclusions
The research findings suggest that KT after 72-h application may improve knee abduction and sum of knee valgus and lateral trunk lean during SLDL, knee flexion during SLDL and SLVDJ in individuals displaying risky single-leg kinematics. Therefore, KT application may marginally improve high-risk landing kinematics in competitive male athletes.

Level of evidence
Level III.
A case of synchronous intramucosal gastric carcinoma with multiple lymph node metastases
Authors: Amada En , Kawakubo Hirofumi , Matsuda Satoru , Mayanagi Shuhei , Nakamura Rieko , Irino Tomoyuki , Wada Norihito , Mikami Shuji , Kitagawa Yuko 
Published: April 2021

Abstract
Background
In Japan, the prevalence of synchronous multiple intramucosal gastric carcinoma is reported to be 5–15%. Here is a case of a synchronous small gastric carcinoma fulfilling the definite indication and curative criteria for endoscopic submucosal dissection with multiple lymph node metastases.

Case presentation
A Japanese woman in her fifties with a history of endoscopic resection for mucosal poorly differentiated adenocarcinoma was evaluated, with the UICC TNM classification stage being cT1aN0M0 cStageIA. She had undergone total gastrectomy with D1 + lymph node dissection. Histopathological examination revealed 16 individual sporadic lesions in the gastric body, with maximum diameter 3 mm and localization in the lamina propria. Twenty-seven nodes were resected, and metastasis of the carcinoma was revealed in 24 nodes.

Conclusions
Undifferentiated intramucosal gastric cancer has a relatively high probability of lymph node metastasis; however, synchronous early lesions are often overlooked. Frequent follow-up examinations may increase the detection of multiple gastric cancers.
The effect of forearm rotation on radiographic measurements of the wrist: an experimental study using radiostereometric analyses on cadavers
Authors: Jensen Janni , Tromborg Hans B. , Rasmussen Benjamin S. B. , Gerke Oke , Torfing Trine , Precht Helle , Graumann Ole 
Published: April 2021

Abstract
Background
Although dorsal/palmar tilt, radial inclination (RI), and ulnar variance (UV) are measurements commonly performed in wrist radiographs, the impact of forearm rotation on those measurements during the radiographic procedure is uncertain. Our aim was to determine the impact of supination and pronation on the reliability of measurements of tilt, RI, and UV.

Methods
Tantalum markers were inserted into the distal radius of 21 unfractured cadaver forearms. The forearms were radiographed in different degrees of supination and pronation. The exact degree of rotation was calculated with radiostereometric analyses. Tilt, RI, and UV were measured by two independent readers in a random and anonymised fashion. Association between forearm rotation and radiographic measurements was examined using linear regression.

Results
Forearm rotation significantly impacted the radiographically measured tilt. One degree of supination and pronation respectively increased and decreased palmar tilt with 0.68° and 0.44°, observers 1 and 2, respectively. As opposed to observer 1, observer 2 found that RI was significantly impacted by rotation with a slope of 0.08. Ulnar variance was not significantly impacted by rotation with linear regression slopes of 0.01° (95% confidence interval [CI] − 0.02–0.05, p = 0.490) and 0.02° (95% CI − 0.02–0.07; p = 0.288), observer 1 and observer 2, respectively.

Conclusion
In unfractured forearms, the radiographically measured tilt was significantly affected by rotation. Palmar tilt increased with supination and decreased with pronation. Rotation significantly affected radial inclination, although of a magnitude that is probably not clinically relevant. No significant impact on UV was found.
Ovarian tissue freezing and activation after thawing: an update
Authors: Peng Li-fan 
Published: April 2021

Abstract
Background
With the growth of women’s age, ovarian failure can be caused by various factors. For the women who need chemotherapy because of cancer factors, the preservation of fertility is more urgent. The treatment of cancer is also a process in which all tissues and organs of the body are severely damaged, especially in the reproductive system.

Main body
As a new fertility preservation technology, autologous ovarian tissue cryopreservation and transplantation is developing rapidly and showing great potentiality in preserving ovarian endocrine function of young cervical cancer patients. Vitrification and slow freezing are two common techniques applied for ovarian tissue cryopreservation. Thus, cryopreserved/thawed ovarian tissue and transplantation act as an important method to preserve ovarian function during radiotherapy and chemotherapy, and ovarian cryopreservation by vitrification is a very effective and extensively used method to cryopreserve ovaries. The morphology of oocytes and granulosa cells and the structure of organelles were observed under the microscope of histology; the hormone content in the stratified culture medium of granulosa cells with the diameter of follicle was used to evaluate the development potential of ovarian tissue, and finally the ovarian tissue stimulation was determined by the technique of ovarian tissue transplantation.

Conclusions
Although there are some limitations, the team members still carry out this review to provide some references and suggestions for clinical decision-making and further clinical research.
Crossroad of infection and autoimmunity in acute liver failure: a case report
Authors: Roy Akash , Taneja Sunil , De Arka , Das Ashim , Duseja Ajay K. , Singh Virendra 
Published: April 2021

Abstract
Background
Acute liver failure (ALF) is a syndromic diagnosis, consisting of jaundice, coagulopathy, and any degree of encephalopathy in a patient without pre-existing liver disease within 26 weeks of the onset of symptoms. Autoimmune hepatitis has a wide range of presentations and can rarely present as ALF, which frequently tends to be autoantibody negative. Tropical infections like dengue, malaria, and leptospirosis, which present as mimickers of ALF, always remain a differential diagnosis of ALF and mandate an etiology specific management. In rare cases, such infections themselves act as a trigger for autoimmunity. We report a case of diagnostic crossroads of infection and autoimmunity, presenting as acute liver failure and describe the challenges in management.

Case presentation
A 25-year-old female presented with a syndromic diagnosis of acute liver failure with possibility of tropical illness-related ALF mimic on account of positive Leptospira serology. After initial improvement, there was a rebound worsening of liver functions which prompted a liver biopsy. Biopsy narrowed the differential to Leptospira-associated hepatitis and severe auto-immune hepatitis. Trial of low dose steroid was given which led to dramatic improvement.

Conclusion
Tropical infections can present as ALF mimics and can themselves act as triggers for autoimmunity. Distinguishing such cases from de-novo acute severe autoimmune hepatitis is difficult and requires therapeutic brinksmanship. An early trial of steroid is mandated but comes with its own challenges.
Damage control of a twin-column pier with a replaceable steel shear link in a cap beam under transverse seismic motion
Authors: Chen Weiting , Bai Xuemeng , Xu Tengfei , Ke Shanshan , Deng Kailai , Xie Haiqing 
Published: April 2021

AbstractThis paper proposes a novel twin-column pier with a steel shear link (SSL) installed in the cap beam to reduce seismic damage in the transverse direction. The SSL interrupts the rigid cap beam and relieves the coupled deformation of the two columns. Benefits of the yieldable SSL in the event of a strong earthquake are the longer effective deformation of a column and limited axial compressive load. A benchmark reinforced-concrete bridge is employed in a seismic performance evaluation to verify the damage reduction performance of the novel twin-column pier with an SSL. Five numerical models, calibrated in a physical component test, are built in ABAQUS; that is, one original bridge and four novel bridges with different SSLs and accompanying configurations. Modal analysis shows that introducing the SSL does not change the overall structural dynamic characteristics. The nonlinear dynamic analysis results indicate that adopting the SSL effectively reduces the peak compressive strain of the reinforced-concrete column, but energy dissipation from the SSL is negligible compared with the total inputted seismic energy. There is no evident change in the macro seismic response of the twin-column pier when using the SSL, such as overall drift and structural damping ratio. Moreover, a transverse continuous main girder is suggested for realizing an additional restoring moment at the column top, which further reduces compressive strain.
Are Regulations Safe? Reflections From Developing a Digital Cancer Decision-Support Tool
Authors: McInerney Ciarán D. , Scott Beverly C. , Johnson Owen A. 
Published: April 2021

PURPOSE Informatics solutions to early diagnosis of cancer in primary care are increasingly prevalent, but it is not clear whether existing and planned standards and regulations sufficiently address patients' safety nor whether these standards are fit for purpose. We use a patient safety perspective to reflect on the development of a computerized cancer risk assessment tool embedded within a UK primary care electronic health record system. METHODS We developed a computerized version of the CAncer Prevention in ExetER studies risk assessment tool, in compliance with the European Union's Medical Device Regulations. The process of building this tool afforded an opportunity to reflect on clinical concerns and whether current regulations for medical devices are fit for purpose. We identified concerns for patient safety and developed nine practical recommendations to mitigate these concerns. RESULTS We noted that medical device regulations (1) were initially created for hardware devices rather than software, (2) offer one-shot approval rather than supporting iterative innovation and learning, (3) are biased toward loss-transfer approaches that attempt to manage the fallout of harm instead of mitigating hazards becoming harmful, and (4) are biased toward known hazards, despite unknown hazards being an expected consequence of health care as a complex adaptive system. Our nine recommendations focus on embedding less-reductionist and stronger system perspectives into regulations and standards. CONCLUSION Our intention is to share our experience to support research-led collaborative development of health informatics solutions in cancer. We argue that regulations in the European Union do not sufficiently address the complexity of healthcare information systems with consequences for patient safety. Future standards and regulations should continue to follow a system-based approach to risk, safety, and accident avoidance.
Patient Knowledge and Expectations About Return of Genomic Results in a Biomarker-Driven Master Protocol Trial (SWOG S1400GEN)
Authors: Roth Joshua A. , Trivedi Meghna S. , Gray Stacy W. , Patrick Donald L. , Delaney Debbie M. , Watabayashi Kate , Litwin Paul , Shah Parth , Crew Katherine D. , Yee Monica , Redman Mary W. , Unger Joseph M. , Papadimitrakopoulou Vassiliki , Johnson Judy , Kelly Karen , Gandara David , Herbst Roy S. , Hershman Dawn L. , Ramsey Scott D. 
Published: April 2021

PURPOSE:Biomarker-driven master protocols represent a new paradigm in oncology clinical trials, but their complex designs and wide-ranging genomic results returned can be difficult to communicate to participants. The objective of this pilot study was to evaluate patient knowledge and expectations related to return of genomic results in the Lung Cancer Master Protocol (Lung-MAP).METHODS:Eligible participants with previously treated advanced non–small-cell lung cancer were recruited from patients enrolled in Lung-MAP. Participants completed a 38-item telephone survey ≤ 30 days from Lung-MAP consent. The survey assessed understanding about the benefits and risks of Lung-MAP participation and knowledge of the potential uses of somatic testing results returned. Descriptive statistics and odds ratios for associations between demographic factors and correct responses to survey items were assessed.RESULTS:From August 1, 2017, to June 30, 2019, we recruited 207 participants with a median age of 67, 57.3% male, and 94.2% White. Most participants “strongly/somewhat agreed” with statements that they “received enough information to understand” Lung-MAP benefits (82.6%) and risks (69.5%). In items asking about potential uses of Lung-MAP genomic results, 87.0% correctly indicated that the results help to select cancer treatment, but < 20% correctly indicated that the results are not used to confirm cancer diagnosis, would not reveal risk of developing diseases besides cancer, and would not indicate if family members had increased cancer risk. There were no associations between sociodemographic factors and proportions providing correct responses.CONCLUSION:In a large National Clinical Trials Network biomarker-driven master protocol, most participants demonstrated incorrect knowledge and expectations about the uses of genomic results provided in the study despite most indicating that they had enough information to understand benefits and risks.
Begging for Rain: Economic and Social Effects of Climate in the Early Koryŏ Period
Authors: Kahm Howard , Lee Dennis 
Published: April 2021

Abstract
As in other premodern societies, the economy and society of Koryŏ Korea (918–1392) were greatly affected by climatological phenomena, particularly rain and drought. However, climate played a critical role in the early formation of Koryŏ, especially in reinforcing a sociocultural belief system that supported monarchical authority. The kings utilized a “menu” of rituals designed to appease Heaven and create favorable climate conditions, which legitimated the temporal and spiritual power of the king. The different rituals can be categorized as personal rituals, private rituals, and public rituals. While climate crises threatened the economic and social stability of Koryŏ society, they were also opportunities for the Koryŏ rulers to display and reaffirm their supreme economic and juridical authority. The kings demonstrated their power by reducing corvée labor and taxes, postponing or eliminating monastery construction, and commuting judicial punishments. While weather and climate were natural phenomena, the social responses to weather were encapsulated in a ritual system that reinforced both the personal responsibility of the king and popular belief in the power and authority of the king to affect the physical and metaphysical environment.
Two Incarnations, One Person: The Complexity of Kim Iryŏp’s Life
Authors: Kim Hwansoo 
Published: April 2021

AbstractKim Iryŏp (Kim Wŏnju, 1896‒1971) was a pioneering feminist and prolific writer who left lay life to become a Buddhist nun. The bifurcation of her life between the secular and religious has generated two separate narratives, with Korean feminist studies focusing on Iryŏp as a revolutionary thinker and Buddhist studies centering on Iryŏp as an influential Buddhist nun. When divided this way, the biography of each career reads more simply. However, by including two significant but unexplored pieces of her history that traverse the two halves of her narrative, Iryŏp emerges as a more complex figure. The first is her forty-five-year relationship with the Buddhist monk Paek Sŏng’uk (1897‒1981). The second is how she extended some of her early feminism into monastic life but said little about the marginalization of nuns in Buddhism’s highly patriarchal system. In both her relationship with Paek and her feminism, Iryŏp drew on the Buddhist teaching of nonself, in which the “big I” is beyond gender. Thus, Iryŏp repositions herself as having attained big I, while Paek remained stuck in “small I.” Yet, while she finds equality with monks through an androgynous big I, none of her writings contest Korean Buddhism’s androcentric institutional structure.
Truths of Traitors: Colonial Collaboration and Autobiographical Narratives in Postliberation Korea
Authors: Kim Ji Young 
Published: April 2021

AbstractThis article examines post-1945 autobiographical writings by alleged pro-Japanese collaborators, focusing on how these ex-colonized Korean writers represented their “shameful” pasts. Autobiographical narratives that confess to writers’ collaborations are customarily interpreted as excuses or self-justifications for collaboration that distort colonial memories. This customary reading of autobiographical writings, based on the factuality and sincerity of the narratives, seems to derive from a preceding literary practice of reading sosŏlga sosŏl (novels about novelists) during the late colonial period, a tacit contract between reader and author of expecting fiction to represent the author’s transparent life narrative. In challenging this mode of reading, this article traces the rhetorical styles and effects and the complexities of the political and ethical implications of two famous confessions of collaboration: Yi Kwangsu’s My Confession and Ch’ae Mansik’s “Sinner of the People.” In doing so, this article demonstrates how specific rhetorical devices produce the sincerity of the autobiographical texts and give closure to the dishonorable colonial past. The author presents a new approach to pro-Japanese collaboration by exploring the arduous task of closure, self-reflection, and decolonization undertaken by Korean writers in the postliberation period, when the decolonizing project was deemed a failure.