bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thinking and Feeling Homosexuality
Authors: Griffiths Craig 
Published: March 2021

Abstract
This chapter puts ambivalence over sex and self-presentation centre-stage, by focusing first on debates over drag and gender transgression, and then on the equivocal position of sex and desire in homosexual politics. While some activists embraced effeminacy for personal and for political reasons, drag was not always compatible with the model of masculinity favoured by many other activists, who sometimes accused Tunten (‘queens’) of endangering the chance of left-wing support. Turning to how sex featured in gay activism, the chapter shows how a shared antipathy to the gay scene, and sites of sexual activity, resembled an important point of connection between gay action groups and more ‘moderate’ homosexual organizations. The final third of the chapter historicizes the emotional politics of gay liberation. After identifying the gay scene as a major culprit for psychological distress in queer life, activists set about imagining alternatives. In this concluding section, the rise of consciousness-raising and self-help groups, and of the first telephone crisis helplines, is set against changing psychological attitudes towards homosexuality.
Conversation Analysis
Authors: Ingram Jenni 
Published: March 2021

Abstract
Conversation analysis offers an inductive approach to the analysis of classroom interaction. With its roots in ethnomethodology, conversation analysis is underpinned by some key principles that focus on how the learning of mathematics is made visible through teachers’ and students’ interactions. Using the tools developed by conversation analysts, the structures and patterns of interaction within mathematics classrooms can be described to reveal what it means to learn, and what it means to do, mathematics in school classrooms. This approach foregrounds what teachers and students themselves treat as learning and doing mathematics and reveals the multifaceted role of interaction in these processes.
The Divine Ideas Tradition in Christian Mystical Theology
Authors: McIntosh Mark A. 
Published: March 2021

Abstract
By the time of early modernity, a widely deployed tenet of Christian thought had begun to vanish. The divine ideas tradition, the teaching that all beings have an eternal existence as aspects of God’s mind, had functioned across a wide range of central Christian doctrines, providing Christian thinkers and mystical teachers with a powerful theological capacity: to illuminate the Trinitarian ground of all creatures, and to renew the divine truth of all creatures through human contemplation. Already by the time of the Middle Platonists, Plato’s forms had been reinterpreted as ideas in the mind of God. Yet that was only the beginning of the transformation of the divine ideas, for Christian belief in God as Trinity and in the incarnation of the Word imbued the divine ideas tradition with a remarkable conceptual agility. The divine ideas teaching allowed mystical theologians to conceive the hidden presence of God in all creatures, and the power of every creature’s truth in God to consummate the full dynamic of every creature’s calling. This book takes the form of a theological essay that brings to life the striking role of the divine ideas tradition in the teaching of its central exponents, and also suggests how the divine ideas might constructively inform Christian theology and spirituality today. Especially in an age of global crises, when the truth of the natural environment, of racial injustice, and of public health is denied and disputed for political ends, the divine ideas tradition affords contemporary thinkers a creative and contemplative vision that reveres the deep truth of all beings and seeks their mending and fulfillment.
Introduction
Authors: McIntosh Mark A. 
Published: March 2021

Abstract
The divine ideas tradition is introduced, not primarily in terms of its philosophical characteristics, but as a theological concept widely employed for most of the history of Christian thought as a way of understanding the communion among creatures and between creatures and God. Contemporary denials and distortions of truth are contrasted with the reverence for truth at the heart of the divine ideas tradition, especially with the tradition’s acknowledgment of the sovereign majesty of beauty, goodness, and truth as created expressions of the divine meaning. The material claims of the divine ideas teaching are explored in terms of the polarity of stances among divine ideas exponents, both with regard to the metaphysical and noetic significance of the ideas. As well, the divine ideas tradition is shown to provide a mode of contemplative understanding that opens doctrine to the mystery to which doctrine directs believers.
The Saving Word of All Things
Authors: McIntosh Mark A. 
Published: March 2021

Abstract
The presence of the divine ideas in the eternal Word permits mystical theologians to consider the cosmic implications of the Incarnation, and also provides a unique mode of understanding the soteriological significance of Christ’s death and resurrection—in which the world’s false construction of creatures is undone and the divine truth of every creature is vindicated. Pseudo-Dionysius, Aquinas, and Catherine of Siena emphasize the Trinitarian matrix of the divine ideas, bringing to light the divine love and delight in all creatures as the motivation for salvation. Maximus and Hadewijch point to the saving encounter between a person’s earthly self, suffering the distortions of sin, and their true identity in God, made possible in Christ. Eriugena, Aquinas, and Bonaventure all employ the divine ideas teaching in order to reflect upon the power of the Word incarnate to re-create the creatures according to God’s eternal knowing and loving of them.
Mitochondrial heat-shock cognate protein 70 contributes to auxin-mediated embryo development
Authors: Li Guichen , Li Zitong , Yang Zeyun , Leshem Yehoram , Shen Yuequan , Men Shuzhen 
Published: March 2021

Abstract
In Arabidopsis thaliana, mitochondrial-localized heat-shock cognate protein 70-1 (mtHSC70-1) plays an important role in vegetativegrowth. However, whether mtHSC70-1 affects reproductive growth remains unknown. Here, we found that the mtHSC70-1 gene was expressed in the provascular cells of the embryo proper from the early heart stage onward during embryogenesis. Phenotypic analyses of mthsc70-1 mutants revealed that mtHSC70 deficiency leads to defective embryo development and that this effect is mediated by auxin. In addition to a dwarf phenotype, the mthsc70-1 mutant displayed defects in flower morphology, anther development, and embryogenesis. At early developmental stages, the mthsc70-1 embryos exhibited abnormal cell divisions in both embryo proper and suspensor cells. From heart stage onward, they displayed an abnormal shape such as with no or very small cotyledon protrusions, had aberrant number of cotyledons, or were twisted. These embryo defects were associated with reduced or ectopic expression of auxin responsive reporter DR5rev:GFP. Consistently, the expression of auxin biosynthesis and polar auxin transport genes were markedly altered in mthsc70-1. On the other hand, mitochondrial retrograde regulation (MRR) was enhanced in mthsc70-1. Treatment of wild-type plants with an inhibitor that activates mitochondrial retrograde signaling reduced the expression level of auxin biosynthesis and polar auxin transport genes and induced phenotypes similar to those of mthsc70-1. Taken together, our data reveal that loss of function of mtHSC70-1 induces MRR, which inhibits auxin biosynthesis and polar auxin transport, leading to abnormal auxin gradients and defective embryo development.
In People With COPD, There Is Limited Evidence That Exercise Training Reduces Sedentary Time, and Behavior Change Techniques Are Poorly Reported: Systematic Review and Meta-Analysis
Authors: Coll Fiona , Cavalheri Vinicius , Gucciardi Daniel F , Wulff Sheldon , Hill Kylie 
Published: March 2021

Abstract

Objective
In people with chronic obstructive pulmonary disease (COPD), the authors sought to explore (1) the effect of any intervention on the time spent in sedentary behavior and, (2) which behavior change techniques (BCTs) have shown promise in achieving this lifestyle target.

Methods
Five electronic databases were searched on January 7, 2021. Studies were included if they (1) recruited people with stable COPD, (2) applied an intervention ≥4 weeks, and (3) measure sedentary time (ST) before and after the intervention period using wearable technology or via self-reports of television viewing. The primary analyses were restricted to data reported in randomized controlled trials (RCTs). All BCTs described during the intervention periods were mapped using an established taxonomy.

Results
Of the 1142 records identified, 8 were RCTs, of which 6 had exercise training as the intervention. Random effects meta-analysis of data from 4 of these 6 trials that implemented exercise training showed no clear effect on ST (mean difference, −3.4 minutes; 95% CI, −27.9–21.0 minutes). Commonly mapped BCTs in the majority of studies included action planning and instruction on how to perform the behavior. Of all the BCTs mapped, 25% were reported with sufficient information to be graded “beyond reasonable doubt.”

Conclusion
Despite robust evidence that exercise training improves functional outcomes and reduces dyspnea, this intervention does not seem to translate into behavior change. The primary analysis demonstrated that, in adults with COPD, the effect of exercise training on ST was, at best, uncertain. The BCTs embedded within the interventions were often poorly reported. Future RCTs are required that appropriately report BCT and ST to improve the precision of our estimate of the effect exercise training may have on ST, and BCTs used during intervention periods need to be reported with greater specificity.

Impact
In people with COPD, there is currently limited evidence to suggest that exercise training will reduce sedentary behavior. To move this area of research forward, BCTs embedded within these interventions need to be described with greater precision.

Lay Summary
In people with COPD, interventions such as exercise training do not seem to produce a reduction in sedentary behavior (ie, time spent sitting or lying down) during daily life. The techniques used to help people change their sedentary behavior were poorly reported, so we do not know what exactly was done and therefore cannot know what may have worked well.
The Fideicommissary Substitution and the Fiducia: Québécois Echoes in the Civil Code of Romania
Authors: Murphy Anthony , Duţă Cristina 
Published: March 2021

Abstract
The current Civil Code of Romania took inspiration from the Civil Code of Quebec in lifting the prohibition on fideicommissary substitutions. In doing so, it also made explicit reference to fiduciary duties when regulating the obligations incumbent on the first beneficiary. This particular provision divided the local literature with some authors embracing the transplant and others criticizing it. Our article argues that the fideicommissary substitution and the fiducia are essentially two sides of the same coin, with said transplant being a welcome development in the Romanian law of succession.
25‐Hydroxycholesterol metabolism is altered by lung inflammation, and its local administration modulates lung inflammation in mice
Authors: Bottemanne Pauline , Paquot Adrien , Ameraoui Hafsa , Guillemot‐Legris Owein , Alhouayek Mireille , Muccioli Giulio G. 
Published: March 2021

AbstractInflammation is a critical component of many lung diseases including asthma and acute lung injury (ALI). Using high‐performance liquid chromatography–mass spectrometry, we quantified the levels of oxysterols in two different murine models of lung diseases. These are lipid mediators derived from cholesterol and known to modulate immunity and inflammation. Interestingly, 25‐hydroxycholesterol (25‐OHC) was the only oxysterol with altered levels during lung inflammation, and its levels were differently affected according to the model. Therefore, we sought to assess how this oxysterol would affect lung inflammatory responses. In a model of lipopolysaccharide (LPS)‐induced acute lung inflammation, 25‐OHC levels were increased, and most of the hallmarks of the model (eg, leukocyte recruitment, mRNA expression, and secretion of inflammatory cytokines) were decreased following its intratracheal administration. We also found that, when administered in the lung, 25‐OHC is metabolized locally into 25‐hydroxycholesterol‐3‐sulfate and 7α,25‐dihydroxycholesterol. Their administration in the lungs did not recapitulate all the effects of 25‐OHC. Conversely, in a model of allergic asthma induced by intranasal administration of house dust mites (HDM), 25‐OHC levels were decreased, and when intranasally administered, this oxysterol worsened the hallmarks of the model (eg, leukocyte recruitment, tissue remodeling [epithelium thickening and peribranchial fibrosis], and cytokine expression) and induced changes in leukotriene levels. Ex vivo, we found that 25‐OHC decreases LPS‐induced primary alveolar macrophage activation while having no effect on neutrophil activation. Its sulfated metabolite, 25‐hydroxycholesterol‐3‐sulfate, decreased neutrophil, but not macrophage activation. Taken together, our data support a differential role of 25‐OHC in ALI and allergic inflammation models.
The RCA ReCAst: A Root Cause Analysis Simulation for the Interprofessional Clinical Learning Environment
Authors: Ziemba Justin B. , Berns Jeffrey S. , Huzinec Jill G. , Bammer Dina , Salva Catherine , Valentine Elizabeth , Myers Jennifer S. 
Published: March 2021

Problem
The Accreditation Council for Graduate Medical Education calls for resident participation in real or simulated interprofessional analysis of a patient safety event. There are far more residents who must participate in these investigations than available institutional root cause analyses (RCAs) to accommodate them. To correct this imbalance, the authors developed an institutionally sponsored, interprofessional RCA simulation program and implemented it across all graduate medical education (GME) residency programs at the Hospital of the University of Pennsylvania.

Approach
The authors developed RCA simulations based upon authentic adverse events experienced at their institution. To provide relevance to all GME programs, RCA simulation cases varied widely and included examples of errors involving high-risk medications, communication, invasive procedures, and specimen labeling. Each simulation included residents and other health care professionals such as nurses or pharmacists whose disciplines were involved in the actual event. Participants adopted the role of RCA investigation team, and in small groups systematically progressed through the RCA process.

Outcomes
A total of 289 individuals from 18 residency programs participated in an RCA simulation in 2019–2020. This included 84 interns (29%), 123 residents (43%), 20 attending physicians (7%), and 62 (21%) other health care professionals. There was an increase in ability of GME trainees to correctly identify factors required for an RCA investigation (62% pre vs 80% post, P = .02) and an increase in intent to “always report” for each adverse event category (3% pre vs 37% post, P < .001) following the simulation.

Next Steps
The authors plan to expand the RCA simulation program to other GME clinical sites while striving to involve all GME learners in this educational experience at least once during training. Additionally, by collaborating with health system patient safety leaders, they will annually review all new RCAs to identify cases suitable for simulation adaptation.
Social and Behavioral Variables in the Electronic Health Record: A Path Forward to Increase Data Quality and Utility
Authors: Lasser Elyse C. , Kim Julia M. , Hatef Elham , Kharrazi Hadi , Marsteller Jill A. , DeCamp Lisa Ross 
Published: March 2021

Purpose
Social and behavioral determinants of health (SBDH) are important factors that affect the health of individuals but are not routinely captured in a structured and systematic manner in electronic health records (EHRs). The purpose of this study is to generate recommendations for systematic implementation of SBDH data collection in EHRs through (1) reviewing SBDH conceptual and theoretical frameworks and (2) eliciting stakeholder perspectives on barriers to and facilitators of using SBDH information in the EHR and priorities for data collection.

Method
The authors reviewed SBDH frameworks to identify key social and behavioral variables and conducted focus groups and interviews with 17 clinicians and researchers at Johns Hopkins Health System between March and May 2018. Transcripts were coded and common themes were extracted to understand the barriers to and facilitators of accessing SBDH information.

Results
The authors found that although the frameworks agreed that SBDH affect health outcomes, the lack of model consensus complicates the development of specific recommendations for the prioritization of SBDH data collection. Study participants recognized the importance of SBDH information and individual health and agreed that patient-reported information should be captured, but clinicians and researchers cited different priorities for which variables are most important. For the few SBDH variables that are captured, participants reported that data were often incomplete, unclear, or inconsistent, affecting both researcher and clinician responses to SBDH barriers to health.

Conclusions
Health systems need to identify and prioritize the systematic implementation of collection of a high-impact but limited list of SBDH variables in the EHR. These variables should affect care and be amenable to change and collection should be integrated into clinical workflows. Improved data collection of SBDH variables can lead to a better understanding of how SBDH affect health outcomes and ways to better address underlying health disparities that need urgent action.
Does Pain Acceptance Buffer the Negative Effects of Catastrophizing on Function in Individuals With Chronic Pain?
Authors: Ferreira-Valente Alexandra , Solé Ester , Sánchez-Rodríguez Elisabet , Sharma Saurab , Pathak Anupa , Jensen Mark P. , Miró Jordi , de la Vega Rocío 
Published: March 2021

Objectives:
Pain catastrophizing and pain acceptance are psychological factors that have been shown to be associated with pain-related outcomes and predict multidisciplinary pain treatment outcomes. However, they are rarely examined in the same study. This study aimed to: (1) assess the independent roles of pain catastrophizingand pain acceptance as predictors of pain intensity, pain interference, and depression; and (2) evaluate the potential moderating role of pain acceptance on the association between pain catastrophizing and both pain and function.

Materials and Methods:
A sample of 467 adults with chronic pain completed an online survey including measures of pain intensity, pain interference, depression, pain catastrophizing, and pain acceptance.

Results:
Pain catastrophizing and pain acceptance were independent predictors of pain interference. Only pain catastrophizing and the activity engagement domain of pain acceptance were independent predictors of pain intensity and depression. Activity engagement moderated the association between pain catastrophizing and depression, indicating a buffering effect on the negative effects of catastrophizing on depression. Pain willingness moderated the association between pain catastrophizing and pain interference, such that endorsing low pain willingness may override any negative effects of pain catastrophizing.

Discussion:
The findings suggest that pain catastrophizing and pain acceptance are independently important to adjustment to chronic pain. Research is needed to determine if treatments that target both for change are more effective than treatments that target only one.
Measurement Properties of the Brief Pain Inventory-Short Form (BPI-SF) and Revised Short McGill Pain Questionnaire Version-2 (SF-MPQ-2) in Pain-related Musculoskeletal Conditions
Authors: Jumbo Samuel U. , MacDermid Joy C. , Kalu Michael E. , Packham Tara L. , Athwal George S. , Faber Kenneth J. 
Published: March 2021

Objective:
The objective of this study was to systematically locate, critically appraise, and summarize clinical measurement research addressing the use of Brief Pain Inventory-Short Form (BPI-SF) and Revised Short McGill Pain Questionnaire Version-2 (SF-MPQ-2) in pain-related musculoskeletal (MSK) conditions.

Materials and Methods:
We systematically searched 4 databases (Medline, CINAHL, EMBASE, and SCOPUS) and screened articles to identify those reporting the psychometric properties (eg, validity, reliability) and interpretability (eg, minimal clinically important difference) of BPI-SF and SF-MPQ-2 as evaluated in pain-related MSK conditions. Independently, 2 reviewers extracted data and assessed the quality of evidence with a structured quality appraisal tool and the updated COSMIN guidelines.

Results:
In all, 26 articles were included (BPI-SF, n=17; SF-MPQ-2, n=9). Both tools lack reporting on their cross-cultural validities and measurement error indices (eg, standard error of measurement). High-quality studies suggest the tools are internally consistent (α=0.83 to 0.96), and they associate modestly with similar outcomes (r=0.3 to 0.69). Strong evidence suggests the BPI-SF conforms to its 2-dimensional structure in MSK studies; the SF-MPQ-2 4-factor structure was not clearly established. Seven reports of high-to-moderate quality evidence were supportive of the BPI-SF known-group validity (n=2) and responsiveness (n=5). One report of high quality established the SF-MPQ-2 responsiveness.

Discussion:
Evidence of high-to-moderate quality supports the internal consistency, criterion-convergent validity, structural validity, and responsiveness of the BPI-SF and SF-MPQ-2 and establishes their use as generic multidimensional pain outcomes in MSK populations. However, more studies of high quality are still needed on their retest reliability, known-group validity, cross-cultural validity, interpretability properties, and measurement error indices in different MSK populations.