bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-19 International Horizon Scanning – informing a response and recovery in Wales and beyond
Authors: Stielke A , Bowles C , Couzens L , Cotter-Roberts A , Allen J , Van Eimeren M , Bainham B , Dyakova M 
Published: October 2021

Abstract

Issue
The rapidly evolving nature and uncertainties of the COVID-19 pandemic have led to unprecedented challenges for health systems, as well as to wellbeing, social and economic impacts for individuals and communities across the globe. Effective, dynamic, innovative and evidence-based solutions are needed to address these challenges.

Description of Problem
The World Health Organization (WHO) Collaborating Centre on Investment for Health and Well-being, Public Health Wales, has initiated and continues to perform International Horizon Scanning work to inform the evolving COVID-19 public health response and recovery plans in Wales by learning from best practices from other countries. The learning and intelligence is systematically synthesized in rapid regular reports published every week/two weeks. The focus and scope vary, depending on the COVID-19 situation and public health and policy needs.

Results
The work stream has provided Welsh Government, the National Health Service (NHS), Public Health Wales and other key stakeholders with continuous and timely learning from the experience of other countries along with emerging evidence and guidance, provided by key international organisations. This includes international evidence, epidemiological data, experience, measures and recovery approaches, to understand and explore solutions. Reports have given a consistent overview of approaches across countries such as a comparative analysis of the vaccine roll-out or a systematic overview of the R-value and measures implemented accordingly.

Lessons
To understand, mitigate and address the impacts of the pandemic in Wales and beyond, a timely, dynamic and evidence-informed actionable intelligence has proven to be essential to inform and support decision-making on government and health system level to address the pandemic and mitigate harms from COVID-19.

Key messages
International learning has and continues to inform the evolving COVID-19 public health response in Wales. Public Health Wales is contributing to an evidence-informed inclusive recovery from the pandemic in Wales and beyond.
Genomic persistence of Listeria monocytogenes strains in dairy and meat processing plants in Italy
Authors: Acciari VA , Del Matto I , Antoci S , Di Marzio V , Torresi M , Iannetti L , Marfoglia C , Centorotola G , Pomilio F 
Published: October 2021

Abstract

Background
Persistence of Listeria monocytogenes (Lm) in food processing plants (FPP) is still considered the major source of food contamination during processing. Correlations among different Lm strains and evaluation of the isolates persistence in FPP environments is an essential tool to improve food safety. The aim of this study was to investigate the genomic characteristics of persistent Lm strains (e.g. Metal and Detergent Resistance, SSIs and genomic island).

Methods
Totally 221 strains isolated from 10 FPP in the Abruzzo and Molise regions, Italy, were enrolled (4 of dairy products FPP - DP - and 6 of meat products FPP - MP). Sampling was performed in 6 sessions, from March 2017 to May 2018. Strains were sequenced using Illumina platform. The CCs, cgMLST analysis and Metal and Detergent Resistance, SSIs and genomic island (GI) detection was carried using the Pasteur scheme.

Results
Results returned 13 CCs and 2 singletons. cgMLST clustering showed two persistent clusters DP and 9 clusters in MP. In DP CC3 and CC9 were persistent. While in MP CC5, CC8, CC9, CC37, CC121 and CC155. The presence of SSI-1, was detected in 100% of the persistent strains from DP and 80% from MP, in particular in all strains of CC155, CC5, CC8 and CC9. In CC121 and CC37 it was absent. The presence of loci of Lm GI3, was in 100% of persistent strains of DP and in 52.3% of MP plant, in particular in 100% of CC121, CC8, CC5 and 16.3% of CC9. The 100% of CC121 in DP and MP plant harboured Tn6188 and SSI-2. The inlA PMSC mutations were detected in 100% of CC9 and CC121 strains.

Conclusions
The persistence of strains inside FPP was confirmed using NGS data, most of the strains were characterised by the presence of genes involved in resistance and adaptation. NGS is confirmed to be a powerful tool to study Lm persistence in FPP, looking also at strains' ecology.

Key messages
Most of persistent strains showed genes involved in resistance and adaptation in the food processing environment. NGS could help in facing Lm persistence in food producing plants giving new insights on the genomic characteristics of persistent strains.
Citizens' knowledge and educational needs in the omics sciences field: results from an Italian survey
Authors: Calabrò GE , Sassano M , Moccia F , Gaudioso A , Ricciardi W , Boccia S 
Published: October 2021

Abstract

Background
Progress in genomics has crucial implications for public health. Therefore, a strategic line to define the promotion and governance of omics related innovation is necessary. In this context, citizens education is essential to allow appropriate decisions about their own health.

Objectives
As part of a project funded by the Italian Ministry of Health, we carried out in collaboration with an Italian civic organization (Cittadinanzattiva) a survey on citizens' attitude, knowledge, and educational needs in omics sciences field. On the basis of the results of two our literature reviews and of a survey with experts of the Italian Network of Genomics in Public Health (GENISAP), we developed an ad hoc questionnaire for citizens. It was developed in order to assess the current state of information on omics field in the Italian population. The survey was launched, through the Cittadinanzattiva channels, on October 29, 2020 and it was closed on April 15, 2021.

Results
As of April 2021, 359 responses have been collected. The average age of the participants was 46.04 ± 15.77 years. 73.5% of the participants had no knowledge of omics sciences and 66.6% of DTC-GTs. As regards the citizens' attitudes, 88.6% would change their lifestyle on the basis of the genetic tests results. 89.2% expressed doubts about the reliability of the information received through the media. Almost all believe that citizens are not adequately informed about omics sciences and DTC-GTs and that more training initiatives are necessary on these topics (omics sciences: 95.5%, DTC-GTs: 95%).

Conclusions
The omics sciences progress is linked to the need to develop a solid literacy of citizens. For this reason, effective tools of knowledge on the omics sciences field will have to be identified and implemented to improve citizens' literacy and engagement in this rapidly changing field.

Key messages
The progress of the omics sciences is related to the need to develop a solid literacy of citizens in order to enable them to make appropriate decisions about their own health. The current challenge is to identify effective methods of improving citizens' literacy and implementing them.
Contribution of research-based pharmaceutical companies in Germany to personalised medicine
Authors: Turulski E , Matusiewicz D 
Published: October 2021

Abstract

Background
The term Personlised Medicine (PM) was introduced to the public more than 20 years ago and was related to tailor-made medicines and a treatment considering the individual human genome. In the meantime, the term PM can be found with various definitions in several different contexts. Considering this, the aim of this research is to analyse the current status of PM in Germany, especially with regard to scientific articles and the pharmaceutical industry.

Methods
First, a systematic literature review was conducted in PubMed and Web of Science. Each search strategy was adapted to the database conditions and consisted of the search terms personalised medicine or the MeSH term precision medicine, additionally pharmaceutical industry and Germany in topic, title or abstract (the Boolean operator AND was applied). Only results in German or English with an available abstract were considered. Second, the websites of all 47 members of the German association of research-based pharmaceutical companies (vfa) were systematically screened referring to their position and communication in terms of PM.

Results
The literature research yielded a total of only 4 results. The scope of the papers is nanomedicine, an interview study and gene disorders. The second research part shows differences on the company websites: More than half of the companies have no relation to PM or an analysis was not possible (n = 25). Some were categorized with indirect relation (n = 3) and on 19 websites PM was communicated in different ways.

Conclusions
The literature research clearly shows that although PM is not a new topic and furthermore, the research of pharmaceutical companies in this area is widely required, the number of scientific articles found is very low. The screening of company websites underlines this result as only 19 of 47 companies take a position to PM here and the scope varies greatly. Nevertheless, it is necessary to examine the reasons and how Germany compares to other countries.

Key messages
Although introduced more than 20 years ago, the appearance of PM by German pharmaceutical companies in scientific articles is quite low. The difference in companies’ communication should be examined.
Which managers make which work accommodations for employees with common mental disorders?
Authors: Bertilsson M , Niederberger R , de Rijk A 
Published: October 2021

Abstract

Background
Work accommodations (WAs) can promote employees' decreased work capacity and work participation. However, little is known about how managers make WAs for employees with common mental disorders (CMD). The aim was to investigate managerial determinants for making WAs for employees with CMD.

Methods
An online survey was sent to 4,737 Swedish managers, aged 20-65 years (response rate 71%). Only managers who stated having had employees with CMD in the last two years responded to questions on WAs, and were included in this study (n = 1779). The 15 WAs in the survey were condensed to seven WA types using principal component analysis. We calculated odd ratios (95% confidence intervals) for the association of person- (n = 5), knowledge- (n = 2) and work-related (n = 10) determinants in relation to WA types with multivariate logistic regression, adjusting for managers' personal experience of CMD, medical training, treating people with CMD, type of industry and organizational size.

Results
Greater confidence in how to support employees with CMD was associated with five different WA types, the strongest OR was found for changes in working conditions (OR 1.87 95% CI 1.48 - 2.38). Female manager was associated with three WA types, the strongest OR was found for changes in working conditions (OR 2.09 95% CI 1.60 - 2.73). Managerial training including knowledge about how to support employees with CMD was associated with four WA types, and the strongest OR was found for accommodating work tasks (OR 1.76 95% CI 1.35 -2.28). Only work sector was associated with more than two WA types, where managers in the private sector were less likely to make three WA types.

Conclusions
Greater confident in how to support these employees, being female, managerial CMD-training and working in the public sector were associated with making WAs more often. The findings suggest directions for training managers in making WAs in order to support and improve work capacity of employees with CMD.

Key messages
Managers’ confidence in and knowledge about how to support employees with CMD were essential in order to make work accommodations. Work-related factors were less associated than expected. Training managers to accommodate the work of employees with CMD might be effective.
Work-Life Balance Inequalities among Veterinary and Allied Professionals: A Qualitative Review
Authors: Ikpeme M , Omotoyinbo F , Toluwade T , Ryan M 
Published: October 2021

Abstract

Background
This study aimed to review qualitative psychological and non-psychologically based literature for work-life balance (WLB) inequalities within the veterinary and other allied professions.

Methods
The PECO framework includes qualitative studies published in any language but with an English translation involving adult workers in the veterinary or allied profession and outcomes around work-life balance. Seven relevant electronic databases EMBASE, PsycARTICLES, PsycINFO, MEDLINE, Social Policy and Practice, HMIC Health Management Information Consortium, and Global Health, were used. The retrieved hits were exported to Endnote Desktop (Version 7.7.1) for sorting and management.

Results
Of the 3610 hits, 31 studies were eligible for narrative synthesis. The studies were published from 1980-2017 and came from 15 countries. 9(29%) of the 31 studies were from the USA. 22 of the 31 studies (71%) focused on a mix of professions. Data were collected in six different ways, with the most common being interviews (17 (54.8%) of 31 studies). Twenty-three questions were used to assess WLB. The most common ones focused on women becoming mothers, maternity leave, and return to work (five (16.1%) of 31 articles). Secondly were attitudes of ethnic minorities concerning education, employment, role-family conflict, etc., and family commitments (three (9.7%) of the 31 papers). Findings came under 74 different topics. Nineteen (25.7%) of the 74 topics occurred more than four times and were allocated under the appropriate sub-theme. The nine sub-themes include pregnancy, breastfeeding, motherhood, job/life satisfaction, age/gender/ethnic inequalities, return to work (RTW), health and lifestyle, dual-earning couples/family, workplace support, and work-family/family-work conflicts.

Conclusions
The review suggests that women, ethnic minorities, older staff, and those with health concerns are negatively impacted by inequalities around WLB in veterinary and allied professions.

Key messages
The findings from the review were used to support the development of psychological measures of work-life balance and gender differences. The results were used in online questionnaires/surveys for future participants within the veterinary profession in addressing inequalities.
Process evaluation of care scale up for hypertension in diabetes in Belgium, Slovenia and Cambodia
Authors: Martens M , Wouters E , Stjepanovič TK , Stojnic N , Chham S , Por I , van Olmen J , Klipstein-Grobusch K , Boateng D ,   SCUBY consortium
Published: October 2021

Abstract

Background
Effective integrated care interventions for hypertension (HT) and type 2 diabetes (T2D) exist and need to be scaled-up. The ‘SCale-Up diaBetes and hYpertension care' SCUBY project aims to facilitate scale-up of integrated care for HT and T2D through the implementation of contextualised scale-up roadmaps in Cambodia, Slovenia and Belgium and co-creation in policy dialogues. We herewith describe the plan for the process and scale-up evaluation of the SCUBY project, including the development, adoption and implementation of the roadmaps. The specific goals of the process evaluation are to (i) analyse how the reality of scale-up adheres to the developed roadmaps and (ii) assess how the different contexts can influence the implementation process of the scale-up strategies.

Methods
A comprehensive framework was developed to include context, process, scale-up and impact evaluation that is embedded in implementation and political theory. A diverse range of mostly qualitative tools - including a policy dialogue reporting form, a stakeholder follow-up interview and survey, project diaries and policy mapping - will be used to assess how stakeholders perceive the scale-up implementation process and adaptations to the roadmap. Key implementation outcomes include acceptability, feasibility relevance, adaptation, adoption and cost of roadmap activities. The role of context is relevant, and barriers and facilitators to scale-up will be continuously assessed.

Conclusions
The SCUBY project presents a comprehensive framework to guide the evaluation of scale-up of complex interventions. We describe three contextualised roadmaps, for Belgium, Slovenia and Cambodia, each adopting their own (horizontal/diversification/vertical) scale-up strategy(ies) as a basis to monitor adaptations through a co-creation process. This study protocol will be a guide for other scale-up interventions making use of knowledge translation and co-creation activities.

Key messages
Process evaluation is needed to keep track of complex interventions including scale up. The SCUBY project developed an evaluation plan to comprehensively monitor the scale-up of HT and T2D care.
The perceptions of construction workers on designing a workplace nutrition intervention in the UK
Authors: Wronska M , Coffey M , Robins A 
Published: October 2021

Abstract

According to the European Commission, construction is an important industry providing the EU with 18 million jobs and contributing to 9% of the EU's GDP in 2020. Construction workers struggle with healthy food choices due to lack of knowledge, long working hours, remote site locations, poor food facilities on site, and temporary accommodation. Yet, nutrition interventions in construction are rare, with no UK studies. This is an exploratory study designed to investigate workers' perceptions of a workplace intervention to facilitate healthy nutrition choices. Engaging participants in the intervention design showed positive results on behaviour change. Five internally homogenous focus groups were conducted on three different construction sites (in three companies); two with managers (n = 11) and three with workers (including subcontractors) (n = 27). Sites differed in size (14; 50-100; and 300 workers); two were temporary. Framework Analysis was used to analyse data. The main themes uncovered in the focus groups were; 1) the need for workers to learn about food to sustain good energy levels, as deemed crucial for their job 2) the desire to get an understanding about portion sizes, food labels, impacts of food on mood and practical ideas of healthy snacks and meal planning and 3) the importance of intervention accessibility for everybody on site (including subcontractors), convenient scheduling and location, and managers support to encourage participation. A participatory approach was used to explore workers' suggestions on the content and delivery of the nutrition intervention. Education and practicality of recommendations were of the essence to workers, who suggested that individual characteristics, the nature of construction jobs (e.g. busy schedules, transient jobs), and resources available (e.g. storage) need to be considered when designing the intervention. Inclusivity, accessibility and managerial support were regarded as valuable in the intervention delivery.

Key messages
This research produced recommendations to encourage the development and implementation of inclusive nutrition interventions in construction, to improve the health and wellbeing of workers. This research invites public health consultants and senior leaders in construction to invest in supporting healthy behaviours of workers, with a consideration of job and workplace characteristics.
Effect of a community-based lifestyle intervention programme on quality of life among German women
Authors: Kranz RM , Englert H 
Published: October 2021

Abstract

Background
Quality of life is an important concept in the field of health, which can be influenced by various lifestyle factors. The objective was to test if a community-based lifestyle programme would beneficially affect the health-related quality of life of German women.

Methods
The controlled intervention study had a total duration of 24 months. Quality of life (EQ-5D-3L), anthropometrics, vital and blood parameters as well as diagnosed diseases and health economic parameters were collected at baseline (t0), after 10 weeks (t1) and after 6 months (t2). For the intervention group (n = 65) a 10-week intensive lifestyle programme followed by monthly alumni meetings were conducted. The intensive phase consisted of 14 consecutive seminars about a healthy lifestyle, which focused on a plant-based diet, physical activity, stress management and community support. The control group (n = 35) received no intervention.

Results
The first descriptive health profile results of the subgroup analysis showed that 59% women of the intervention group at t0 (t1: 37%; t2: 48%) and 60% of the control group at t0 (t1: 54%; t2: 49%) reported problems in at least one of the EQ-5D dimensions (mobility, selfcare, activities, pain, and anxiety). A significant difference in EQ VAS change between women in intervention (7,15 [95% CI 4,32; 9,98]; EQ VAS t0: 75,35 [SD 13,71]) and control group (-2,63 [95% CI -5,40; 0,15]; EQ VAS t0: 78,80 [SD 18,51]) from t0 to t1 was observed (p &lt; 001; adjusted for baseline). No significant differences in mean EQ VAS change from t0 to t2 and in mean EQ-5D index change from t0 to t1 and t0 to t2 between the groups were observed (p &gt; 0,05; adjusted for baseline).

Conclusions
The preliminary results suggest that the lifestyle intervention programme can have a positive short-time effect on some aspects of quality of life, such as the health profile and EQ VAS. However, the long-term results will be shown in the future.

Key messages
A healthy lifestyle can affect the quality of life in a positive way. The community-based lifestyle programme had a short-time influence on the descriptive health profile and EQ VAS of German women, whereby the EQ index didńt change significantly between the groups.
A systematic review of the determinants of the nutritional quality of food for homeless populations
Authors: Ravikumar D , Nic Gabhann S , Kelly C 
Published: October 2021

Abstract

Introduction
Studies assessing the nutritional quality of food provided to homeless population show deficiencies in micronutrients and excess fat, sugar and salt. The availability of cheap, energy-dense and nutrient poor food has changed the profile of people living with homelessness from primarily underweight to obese in western countries. Many factors influence the nutritional quality of food provided to the homelessness population such as budget and time constraints, food donations and limited equipment. Nutrient intakes in this population are unlikely to be met outside of charitable meal programmes, making the nutritional quality of these meals crucial. This review will synthesise qualitative literature with the aim of understanding of the determinants of the nutritional quality of food provided to the homeless population.

Methods
This qualitative evidence synthesis will include English language primary research empirical studies from Europe, North America and Oceania. Searches will be conducted on Web of Science, CINAHL, Embase, Scopus, PsycINFO, Google Scholar, OpenGrey and ProQuest. Quality appraisal will be conducted using the Standards for Reporting Qualitative Research tool. Two independent reviewers will be included in study selection, data extraction and quality appraisal. A third reviewer will resolve conflicts.

Results
Demographic data on study participants and findings and quotations will be extracted. Thematic synthesis will be employed. Results will be organised based on a determinants of health model, to highlight areas where change may be effective, thereby making it more likely to be useful to practitioners and researchers. The iterative steps in the systematic review process will be the focus of this presentation.

Conclusions
Findings from this review will be used to develop best-practice guidelines for policy makers and service providers to improve the nutritional quality of food provided in the homeless sector.

Key messages
The determinants of the nutritional quality of food provided to the homeless population are influenced by multiple factors. This review will provide a comprehensive assessment of these determinants. This presentation will detail the iterative steps undertaken to conduct this systematic review.