bluuebunny/crossref_metadata_2025_split huggingface dataset:
SOCIO-SCIENTIFIC STUDY: RELATIONSHIP OF STUDENTS' SOCIAL INTERACTIONS WITH NATURAL SCIENCES LEARNING OUTCOMES
Authors: Maulyda Mohammad Archi , Erfan Muhammad 
Published: December 2021

Social interactions that occur between individuals in natural sciences are called socio-scientific. Socio-scientific norms are rules derived from mathematical values brought into the social context. norms are seen as being able to increase students' understanding. The main focus in this research are, (1) Analyzing social content in elementary natural sciences learning courses; (2) Describe the process of social interaction on research subjects; and (3) describe the relationship between social interaction and natural sciences learning outcomes. This type of research is quantitative with a descriptive approach. Study subjects was 100 prospective elementary school teachers. Data collection techniques was using survey methods and analysis of student’s final exam in natural sciences test. Data analysis uses simple linear regression analysis. From the research, the results are obtained: (1) Mathematical content in the lecture process has been raised by the lecturer. The lecture system in the form of group discussions can improve students' communication, courage and collaboration skills. (2) The description of students' social interactions can be modeled. Social interaction models show social interaction can be in the form of associative and dissociative. (3) There is a relationship between social interaction with learning outcomes in natural sciences. The relationship is quite strong, and social interaction influences student natural sciences learning outcomes
Analisis Pola dan Intensitas Curah Hujan Berdasarkan Data TRMM di Sulawesi Tenggara
Authors: Erna Erna , Muliddin Muliddin , Harimudin Jamal 
Published: December 2021

Abstrak: Cuaca dan iklim merupakan sebuah proses fenomena di atmosfer yang keberadaannya sangat penting dalam berbagai aktivitas kehidupan. Perhatian mengenai informasi cuaca dan iklim semakin meningkat seiring dengan meningkatnya fenomena alam yang tidak lazim terjadi atau biasa disebut dengan cuaca ekstrim yang sulit untuk dikendalikan dan dimodifikasi. Penelitian ini bertujuan untuk mengetahui pola dan intensitas curah hujan berdasarkan data TRMM di Sulawesi Tenggara berdasarkan aspek temporal. Metode analisis data yaitu analisis korelasi dan uji signifikan untuk mengetahui hubungan data TRMM dengan data stasiun curah hujan, serta menggunakan persamaan Mononobe untuk intensitas curah hujan. Hasil penelitian ini didapatkan bahwa pola hujan di Sulawesi Tenggara merupakan pola region A tipe monsunal dengan ciri terjadi puncak musim hujan yang terjadi antara bulan Desember, Januari, Februari dan puncak musim kemarau terjadi antara Bulan Agustus dan September. Kecendrungan intensitas curah hujan mengalami kenaikan dengan kala ulang yang lebih lama. Kata Kunci: Curah Hujan, TRMM, Monsunal Abstract: Weather and climate are a process of phenomena in the atmosphere whose existence is very important in various activities life. Concern about weather and climate information is increasing along with the increase in natural phenomena that are not uncommon or commonly referred to as extreme weather that are difficult to control and modify . This study aims to determine rainfall patterns and intensity based on TRMM data in Southeast Sulawesi based on temporal aspects. Data analysis method is correlation analysis and significant test to determine the relationship of TRMM data with rainfall station data, and using the Mononobe equation for rainfall intensity. The results of this study found that the pattern of rain in Southeast Sulawesi is a type of Region A Monsunal pattern characterized by the peak of the rainy season which occurs between December, January, February and the peak of the dry season occurs between August and September. The intensity of rainfall increases with a longer return period. Keywords: Precipitation, TRMM, Monsoonal
Prediksi Perubahan Lahan Terbangun Dengan OBIA LCM Pada Citra Terfusi di Kota Kendari
Authors: Adnan Adnan , Saleh Fitra , Salihin Iradat 
Published: December 2021

Abstrak: Penggunaan lahan disetiap tahunnya akan mengalami perubahan. Perkembangan tersebut bisa jadi tidak terkendali, sehingga perencanaan prediksi perubahan lahan penting untuk dikaji. Dalam memprediksi dapat dilakukan dengan menggunakan citra, khususnya citra Landsat. Penelitian ini bertujuan untuk: (1) distribusi penggunaan lahan terbangun di Kota Kendari pada tahun 2014 dan 2019 dengan metode OBIA pada citra terfusi; (2) melihat arah perubahan penggunaan lahan terbangun di Kota Kendari pada tahun 2024 dan 2029 dengan metode Land Change Modeler (LCM). Metode yang digunakan dalam penelitian ini yaitu metode klasifikasi penggunaan lahan berbasis piksel OBIA dan pemodelan prediksi perubahan penggunaan lahan Land Change Modeler (LCM). Hasil penelitian ini antara lain: (1) luas lahan terbangun pada tahun 2014 di Kota Kendari seluas 6.061,85 hektar dan luas penggunaan lahan terbangun di Kota Kendari pada tahun 2019 seluas 6.716,96 hektar dengan perubahan penggunaan lahan terbangun tahun 2014 sampai dengan tahun 2019 dengan pertambahan luas 2,43%; (2) Arah perubahan penggunaan lahan terbangun di Kota Kendari diprediksikan cenderung berkembang ke arah Kecamatan Baruga karena dipengaruhi oleh dua faktor yaitu kemiringan lereng dan jaringan jalan. Kata Kunci : Penggunaan Lahan, Landsat 8 OLI, Penajaman Citra, OBIA, LCM Abstract: Land use will change every year. The development may be uncontrollable, so predictive planning of land changes is important to review. In predicting can be done using imagery, especially Landsat imagery. This study aims to:(1) the distribution of land use built in Kendari City in 2014 and 2019 with OBIA method on diffusion imagery; (2) see the direction of land use changes built in Kendari City in 2024 and 2029 with land change modeler (LCM) method. The methods used in this study are OBIA pixel-based land use classification method and land use change prediction modeling land change modeler (LCM). The results of this study include: (1) land area built in 2014 in Kendari City aswide as 6,061.85 hectars and land use area built in Kendari City in 2019 aswide as 6,716.96 hectars with land use changes built in 2014 to 2019 with an increase of 2.43%; (2) The direction of land use changes built in Kendari City is predicted to tend to develop towards Baruga Subdistrict because it is influenced by two factors, namely slope and road network. Keywords: Land Use, Landsat 8 OLI, Image Sharpening, OBIA, LCM
Peran Apoteker Terhadap Keberhasilan Pengobatan Tahap Intensif Pasien Tuberkulosis
Authors: Utukaman Katharina Aditya Candra , Laksmitawati Dian Ratih , Sumarny Ros , Tomasoa Edwin 
Published: December 2021

Penelitian ini bertujuan untuk mengetahui pengaruh edukasi dan monitoring pengobatan tuberkulosis pada PKM dengan intervensi Apoteker (PKM Saumlaki) dan PKM tanpa intervensi Apoteker (PKM Larat). Responden penelitian ini adalah pasien baru TB dan Pengawas Menelan Obat (PMO) di kedua PKM pada bulan September-November 2020. Penelitian ini merupakan jenis penelitian quasi experimental dengan rancangan two group pretest-posttest design. Peran apoteker berupa edukasi dan monitoring dilakukan pada responden PKM Saumlaki selama 8 minggu observasi. Data dikumpulkan dalam bentuk kuesioner dan data catatan pengobatan di PKM masing-masing. Hasil penelitian menunjukkan karakteristik demografi responden di kedua PKM tidak berbeda bermakna. Perbedaan bermakna antara kedua PKM terdapat pada data pengetahuan, kepatuhan, outcome klinis berdasarkan BTA negative pada akhir pengobatan tahap intensif, dan data kepuasan pasien terhadap PMO. Sedangkan efek samping dan berat badan pasien antara kedua PKM tidak berbeda bermakna. Hal ini menandakan ada pengaruh edukasi dan monitoring oleh apoteker terhadap peningkatan jumlah pasien yang berhasil menjalani pengobatan TB. Analisis mengenai faktor yang signifikan berhubungan dengan keberhasilan pengobatan memberikan hasil bahwa faktor yang signifikan berpengaruh adalah adanya intervensi apoteker pada tingkat kepatuhan pasien, tingkat pengetahuan pasien dan PMO. Kesimpulan yaitu edukasi dan monitoring pengobatan langsung oleh apoteker pada pasien TB di PKM Saumlaki di KKT berpengaruh meningkatkan keberhasilan pengobatan pasien tuberkulosis
Hubungan Kinerja Perawat terhadap Implementasi Penerapan Keselamatan Pasien di Masa Pandemi Covid-19
Authors: Ameliyah Ayu Rizky , Nursapriani Nursapriani 
Published: December 2021

Tujuan penelitian ini untuk menganalisis hubungan kinerja perawat terhadap implementasi penerapan keselamatan pasien di masa pandemi Covid-19 pada RSUD Labuang Baji Kota Makassar. Metode penelitian ini menggunakan metode penelitian kuantitatif dengan pendekatan cross sectional. Pengumpulan data menggunakan kuesioner. Sampel dalam peneliian ini adalah seluruh perawat Instalasi Rawat Inap RSUD Labuang Baji sebanyak 100 orang. Analisis data dengan menggunakan uji chi square yaitu untuk melihat hubungan antar variabel independen dan variabel dependen. Hasil penelitian menunjukkan bahwa ada hubungan pengetahuan perawat dengan nilai p= 0.008 (p<0.05), beban kerja perawat dengan nilai p= 0.02 (p<0.05), serta motivasi kerja dengan nilai p= 0.01 (p<0.05) terhadap implementasi keselamatan pasien. Adapun faktor kinerja perawat yang paling kuat berhubungan terhadap implementasi keselamatan pasien yaitu faktor beban kerja perawat dengan nilai Exp (B) 4.504, yang artinya beban kerja berhubungan 4.5 kali lipat terhadap implementasi keselamatan pasien. Diharapkan RSUD Labuang Baji dapat meningkatkan pelaksanaan pendidikan dan pelatihan keselamatan pasien serta pimpinan dapat memberikan motivasi yang tinggi terhadap implementasi penerapan keselamatan pasien.
Integrative 5-Methylcytosine Modification Immunologically Reprograms Tumor Microenvironment Characterizations and Phenotypes of Clear Cell Renal Cell Carcinoma
Authors: Xu Wenhao , Zhu Wenkai , Tian Xi , Liu Wangrui , Wu Yuanyuan , Anwaier Aihetaimujiang , Su Jiaqi , Wei Shiyin , Qu Yuanyuan , Zhang Hailiang , Ye Dingwei 
Published: December 2021

The tumor microenvironment (TME) affects the biologic malignancy of clear cell renal cell carcinoma (ccRCC). The influence of the 5-methylcytosine (m5C) epigenetic modification on the TME is unknown. We comprehensively assessed m5C modification patterns of 860 ccRCC samples (training, testing, and real-world validation cohorts) based on 17 m5C regulators and systematically integrated the modification patterns with TME cell-infiltrating characterizations. Our results identified distinct m5C modification clusters with gradual levels of immune cell infiltration. The distinct m5C modification patterns differ in clinicopathological features, genetic heterogeneity, patient prognosis, and treatment responses of ccRCC. An elevated m5C score, characterized by malignant biologic processes of tumor cells and suppression of immunity response, implies an immune-desert TME phenotype and is associated with dismal prognosis of ccRCC. Activation of exhausted T cells and effective immune infiltration were observed in the low m5C score cluster, reflecting a noninflamed and immune-excluded TME phenotype with favorable survival and better responses to immunotherapy. Together, these findings provide insights into the regulation mechanisms of DNA m5C methylation modification patterns on the tumor immune microenvironment. Comprehensive assessment of tumor m5C modification patterns may enhance our understanding of TME cell-infiltrating characterizations and help establish precision immunotherapy strategies for individual ccRCC patients.
Histologically Confirmed Recellularization is a Key Factor that Affects Meniscal Healing in Immature and Mature Meniscal Tears
Authors: Yan Wenqiang , Dai Wenli , Cheng Jin , Fan Yifei , Zhao Fengyuan , Li Yuwan , Maimaitimin Maihemuti , Cao Chenxi , Shao Zhenxing , Li Qi , Liu Zhenlong , Hu Xiaoqing , Ao Yingfang 
Published: December 2021

Healing outcomes of meniscal repair are better in younger than in older. However, exact mechanisms underlying superior healing potential in younger remain unclear from a histological perspective. This study included 24 immature rabbits and 24 mature rabbits. Tears were created in the anterior horn of medial meniscus of right knee in each rabbit. Animals were sacrificed at 1, 3, 6, and 12 weeks postoperatively. We performed macroscopic and histological evaluations of post-meniscal repair specimens. Cells were counted within a region of interest to confirm cellularization at tear site in immature menisci. The width of cell death zone was measured to determine the region of cell death in mature menisci. Apoptosis was evaluated by TUNEL assay. Vascularization was assessed by CD31 immunofluorescence. The glycosaminoglycans and the types 1 and 2 collagen content was evaluated by calculating average optical density of corresponding histological specimens. Cartilage degeneration was also evaluated. Healing outcomes following untreated meniscal tears were superior in immature group. Recellularization with meniscus-like cell morphology was observed at tear edge in immature menisci. Superior recellularization was observed at meniscal sites close to joint capsule than at sites distant from the capsule. Recellularization did not occur at tear site in mature group; however, we observed gradual enlargement of cell death zone. Apoptosis was presented at 1, 3, 6, 12 weeks in immature and mature menisci after untreated meniscal tears. Vascularization was investigated along the tear edges in immature menisci. Glycosaminoglycans and type 2 collagen deposition were negatively affected in immature menisci. We observed glycosaminoglycan degradation in mature menisci and cartilage degeneration, specifically in immature cartilage of the femoral condyle. In conclusion, compared with mature rabbits, immature rabbits showed more robust healing response after untreated meniscal tears. Vascularization contributed to the recellularization after meniscal tears in immature menisci. Meniscal injury fundamentally alters extracellular matrix deposition.
UV-Induced Formation of Ice XI Observed Using an Ultra-High Vacuum Cryogenic Transmission Electron Microscope and its Implications for Planetary Science
Authors: Kouchi Akira , Kimura Yuki , Kitajima Kensei , Katsuno Hiroyasu , Hidaka Hiroshi , Oba Yasuhiro , Tsuge Masashi , Yamazaki Tomoya , Fujita Kazuyuki , Hama Tetsuya , Takahashi Yukihiro , Nakatsubo Shunichi , Watanabe Naoki 
Published: December 2021

The occurrence of hydrogen atom-ordered form of ice Ih, ice XI, in the outer Solar System has been discussed based on laboratory experiments because its ferroelectricity influences the physical processes in the outer Solar System. However, the formation of ice XI in that region is still unknown due to a lack of formation conditions at temperatures higher than 72 K and the effect of UV-rays on the phase transition from ice I to ice XI. As a result, we observed the UV-irradiation process on ice Ih and ice Ic using a newly developed ultra-high vacuum cryogenic transmission electron microscope. We found that ice Ih transformed to ice XI at temperatures between 75 and 140 K with a relatively small UV dose. Although ice Ic partially transformed to ice XI at 83 K, the rate of transformation was slower than for ice Ih. These findings point to the formation of ice XI at temperatures greater than 72 K via UV irradiation of ice I crystals in the Solar System; icy grains and the surfaces of icy satellites in the Jovian and Saturnian regions.
Clinical Outcomes of Computational Virtual Mapping-Guided Catheter Ablation in Patients With Persistent Atrial Fibrillation: A Multicenter Prospective Randomized Clinical Trial
Authors: Baek Yong-Soo , Kwon Oh-Seok , Lim Byounghyun , Yang Song-Yi , Park Je-Wook , Yu Hee Tae , Kim Tae-Hoon , Uhm Jae-Sun , Joung Boyoung , Kim Dae-Hyeok , Lee Moon-Hyoung , Park Junbeom , Pak Hui-Nam ,   the CUVIA-AF 2 Investigators
Published: December 2021

Background: Clinical recurrence after atrial fibrillation catheter ablation (AFCA) still remains high in patients with persistent AF (PeAF). We investigated whether an extra-pulmonary vein (PV) ablation targeting the dominant frequency (DF) extracted from electroanatomical map–integrated AF computational modeling improves the AFCA rhythm outcome in patients with PeAF.Methods: In this open-label, randomized, multi-center, controlled trial, 170 patients with PeAF were randomized at a 1:1 ratio to the computational modeling-guided virtual DF (V-DF) ablation and empirical PV isolation (E-PVI) groups. We generated a virtual dominant frequency (DF) map based on the atrial substrate map obtained during the clinical AF ablation procedure using computational modeling. This simulation was possible within the time of the PVI procedure. V-DF group underwent extra-PV V-DF ablation in addition to PVI, but DF information was not notified to the operators from the core lab in the E-PVI group.Results: After a mean follow-up period of 16.3 ± 5.3 months, the clinical recurrence rate was significantly lower in the V-DF than with E-PVI group (P = 0.018, log-rank). Recurrences appearing as atrial tachycardias (P = 0.145) and the cardioversion rates (P = 0.362) did not significantly differ between the groups. At the final follow-up, sinus rhythm was maintained without any AADs in 74.7% in the V-DF group and 48.2% in the E-PVI group (P &lt; 0.001). No significant difference was found in the major complication rates (P = 0.489) or total procedure time (P = 0.513) between the groups. The V-DF ablation was independently associated with a reduced AF recurrence after AFCA [hazard ratio: 0.51 (95% confidence interval: 0.30–0.88); P = 0.016].Conclusions: The computational modeling-guided V-DF ablation improved the rhythm outcome of AFCA in patients with PeAF.Clinical Trial Registration: Clinical Research Information Service, CRIS identifier: KCT0003613.
Retrieving the Soil Moisture in Bare Farmland Areas Using a Modified Dubois Model
Authors: Ma Teng , Han Ling , Liu Quanming 
Published: December 2021

Soil moisture is an important parameter for global soil moisture transport, environmental evaluation, and precision agricultural research. The accurate retrieval of soil moisture in farmland areas using Synthetic Aperture Radar (SAR) depends on the accurate description of surface and SAR parameters. In these parameters, surface roughness and incidence angle are the key factors that affect the accuracy of the soil moisture retrieval model. This article proposes a modified Dubois model to retrieve soil moisture suitable for the bare surface of farmland area. The model eliminates the incidence angle parameters and uses polarization parameters to depict the surface roughness parameters in the Dubois model. To eliminate the incidence angle, the backscattering coefficients gamma0, which eliminates the effect of the incidence angles, are used to replace the sigma0. Under rain and no rain condition, the trend of backscattering coefficients (VH and VV) and cross-polarization ratio (VH-VV) of different soil texture with the soil moisture are compared. Then, the polarization parameter based on VH backscattering coefficients is used to describe surface roughness. The model is evaluated with time-series soil moisture observation data in situ of the study area. The results indicate that the modified model can retrieve soil moisture with high accuracy, and the total RMSE can reach 0.064 cm3cm−3 while the Dubois model is 0.124 cm3cm−3. Under rain and no rain condition, the retrieval accuracy of the modified model is 0.066 cm3cm−3 and 0.063 cm3cm−3. The retrieval accuracy is 0.060 cm3cm−3 and 0.067 cm3cm−3 under high and low incidence angles conditions, respectively. These results indicate that the modified Dubois model can retrieve soil moisture with high accuracy under different conditions.
Quantitative Policy Analysis for Sustainable Aviation Fuel Production Technologies
Authors: Wang Z. Juju , Staples Mark D. , Tyner Wallace E. , Zhao Xin , Malina Robert , Olcay Hakan , Allroggen Florian , Barrett Steven R. H. 
Published: December 2021

This paper quantifies the impact of different policy options on the economic viability of sustainable aviation fuel (SAF) production technologies. The pathways considered include isobutanol to jet from corn grain, hydroprocessed esters and fatty acids (HEFA) from inedible fats and oils, HEFA from palm fatty acid distillate, synthesized iso-paraffins from sugarcane, Fischer-Tropsch (FT) gasification and synthesis from municipal solid waste, and micro FT from wood residues. The policies considered include feedstock subsidies, capital grants, output based incentives, and two policies intended to reduce project risk. Stochastic techno-economic analysis models are used to quantify the policies’ impact on project net present value and minimum selling price of the middle distillate fuel products. None of the technology pathways studied are found to be financially viable without policy aid. The median total policy costs required for economic viability range from 35 to 337 million USD per production facility, or 0.07–0.71 USD/liter. Our results indicate that the cumulative impact of multiple policies, similar in magnitude to analogous real-world fuel policies, could result in economically viable SAF production.
Polarity Dependence of Transport of Pharmaceuticals and Personal Care Products Through Birnessite-Coated Porous Media
Authors: Li Ye , Zhuang Jie , Essington Michael E. , Chen Xijuan 
Published: December 2021

Pharmaceuticals and personal care products (PPCPs) have drawn increasing concern of environmental health as they are continuously released into the environment. This study examined the effects of birnessite (δ-MnO2) on the transport and retention of five PPCPs in porous media under steady saturated flow conditions. Considering that natural birnessite occurs as discrete particles and small nodules, birnessite-coated sand was used to mimic the natural regime of birnessite in the environment. Batch isotherm experiments were conducted using uncoated and birnessite-coated sand; results showed that the difference in the affinity of the five PPCPs was correlated to their polarity characteristics. Column experiments were conducted by mixing 0, 10, and 20% birnessite-coated sands with the uncoated sands. These three percentages are equivalent to three contents of manganese (Mn) in the experimental columns (0, 55, and 109 μg Mn g−1 sand). Results suggested that polar compounds (such as bisphenol-A, tetracycline, and ciprofloxacin) had a higher affinity to birnessite-coated sands than the weak polar compounds (such as ibuprofen and carbamazepine) because the polarity was favorable to electrostatic attraction and oxidative reaction. Overall, birnessite decreased the mobility of polar PPCPs but exerted no significant effect on the mobility of weak polar PPCPs under continuous flow conditions. The polarity-based correlation extended traditional electrostatic theory while well interpreting the complicated effects of birnessite on the adsorption and transport of PPCPs, especially neutral or non-dissociated compounds like carbamazepine.