bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Post-Drying Tempering of Rice on Minimizing Kernel Fissuring and Maximizing Moisture Removal
Authors: Odek Zephania , Siebenmorgen Terry J. , Mauromoustakos Andronikos , Atungulu Griffiths G. 
Published: December 2021

HighlightsMore moisture can be removed in a single drying pass without severely fissuring kernels when samples are tempered than when immediately cooled without tempering.Tempering rice kernels immediately after drying can reduce the percentage of fissured kernels by up to half of that when kernels are immediately cooled without tempering.Abstract. Improper rice drying results in kernel fissuring, leading to head rice yield reduction due to breakage during milling. The objective of this study was to determine the percentage points (pp) of moisture content (MC) reduction that can be achieved in a single drying pass without significantly fissuring kernels. Long-grain rough rice of cultivars CL XL745 and Diamond at initial MCs of 18%, 17%, 16%, 15%, and 14% were dried using air at 45°C/20% relative humidity (RH), 50°C/15% RH, 55°C/12% RH, 60°C/10% RH, and 65°C/8% RH to MCs of 17%, 16%, 15%, 14%, 13%, or 12% with and without post-drying tempering. All temperature/RH combinations resulted in a humidity ratio of 0.012 kg water kg-1 dry air. Tempering was conducted at the drying air temperature for 4 h. The resulting samples achieved between 1 and 7 pp of MC reduction in a single drying pass. The pp of MC reduction that can be attained in a single drying pass without causing significant fissuring varied across the cultivars tested. Generally, ~2 pp of MC reduction was achieved in a single drying pass for CL XL745 and ~4 pp for Diamond without causing adverse fissuring when samples were not tempered after drying. However, with tempering, ~3.5 pp of MC reduction was achieved in a single drying pass for CL XL745 and ~5.5 pp for Diamond without causing significant fissuring. However, these amounts varied depending on the drying air conditions and initial MC. For both cultivars, tempering immediately after drying reduced the fissured kernel percentage by up to half of that when the kernels were not tempered. These findings quantify the importance of rice tempering and provide information on how much moisture can be safely removed in a single drying pass. Such findings may be applied to different dryer types to reduce fissuring due to drying, thereby minimizing head rice yield reductions. Keywords: Drying, Glass transition, Rice quality, Single-pass drying, X-ray imaging.
Combined mRNAs and clinical factors model on predicting prognosis in patients with triple-negative breast cancer
Authors: Hu Yanjun , Zou Dehong 
Published: December 2021

ObjectiveTriple-negative breast cancer (TNBC) is aggressive cancer usually diagnosed in young women with no effective prognosis prediction model to use. The present study was performed to develop a useful prognostic model for predicting overall survival (OS) for TNBC patients.MethodsThe Cancer Genome Atlas (TCGA) and Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) databases were used as training and validation data sets, respectively, in which the gene expression levels and clinical prognostic information of TNBC were collected. Differentially expressed genes (DEGs) between TNBC and non-TNBC (NTNBC) were identified with the thresholds of false discovery rate < 0.05 and |log2Fold Change| > 1. DEGs in AmiGO2 and the Kyoto Encyclopedia of Genes and Genomes (KEGG) databases were retained for further study. Univariate, multivariate Cox, and logistic regression analysis were conducted for detecting DEG signature with the threshold of log-rankP< 0.05. The prognosis models of mRNA signature, clinical factors were constructed and compared.ResultsOne five-DEG signature, includingCHST4,COCH,CST9,SOX11, andTDGF1was identified in DEG prognosis model. Stratified analysis showed that the patients aged over 60, with higher pathologic stage (III-IV) and recurrence induced a significantly lower survival rate than those aged below 60, lower pathologic stage and without recurrence. Compared with patients with low-risk scores, those presented high-risk scores demonstrated significantly lower survival rate in the subgroup aged over 60 [HR = 3.780 (1.801–7.933),P< 0.0001]. For patients who obtained a higher pathologic stage and recurrence, high-risk scores were correlated with a significantly lower survival rate than patients with low-risk scores. The five-mRNA signature combined with clinical model (AUC = 0.950) predicted better than single clinical model (AUC = 0.795) or five-mRNA signature model (AUC = 0.823).ConclusionOur present study identified a prognostic prediction model (combined with five-mRNA signature and clinical factors) for TNBC patients receiving immunotherapy, which will benefit future research and clinical therapies.
Circulating sLR11 levels predict severity of pulmonary hypertension due to left heart disease
Authors: Joki Yusuke , Konishi Hakuoh , Ebinuma Hiroyuki , Takasu Kiyoshi , Minamino Tohru 
Published: December 2021

Background
Heart failure is a severe condition often involving pulmonary hypertension (PH). Soluble low-density lipoprotein receptor with 11 ligand-binding repeats (sLR11) has been associated with pulmonary artery hypertension. We examined whether sLR11 correlates with PH in left heart disease and can be used as a predictive marker.

Method
We retrospectively analyzed patients with severe mitral regurgitation who underwent right heart catheterization before surgery for valve replacement or valvuloplasty from November 2005 to October 2012 at Juntendo University. We measured sLR11 levels before right heart catheterization and analyzed correlations with pulmonary hemodynamics. We compared prognoses between a group with normal sLR11 (≤9.4 ng/ml) and a group with high sLR11 (>9.4 ng/ml). Follow-up was continued for 5 years, with end points of hospitalization due to HF and death due to cardiovascular disease.

Results
Among 34 patients who met the inclusion criteria, sLR11 correlated with mean pulmonary artery pressure (r = 0.54, p<0.001), transpulmonary pressure gradient (r = 0.42, p = 0.012), pulmonary vascular resistance (r = 0.36, p<0.05), and log brain natriuretic peptide (BNP). However, logBNP did not correlate with pulmonary vascular resistance (p = 0.6). Levels of sLR11 were significantly higher in the 10 patients with PH (14.4±4.3 ng/ml) than in patients without PH (9.9±3.9 ng/ml; p = 0.002). At 5 years, the event rate was higher in the high-sLR11 group than in the normal-sLR11 group. The high-sLR11 group showed 5 hospitalizations due to HF (25.0%) and 2 deaths (10.0%), whereas the normal-sLR11 group showed no hospitalizations or deaths. Analyses using receiver operating characteristic curves showed a higher area under the concentration-time curve (AUC) for sLR11 level (AUC = 0.85; 95% confidence interval (CI) = 0.72–0.98) than for BNP (AUC = 0.80, 95%CI = 0.62–0.99) in the diagnosis of PH in left heart disease.

Conclusions
Concentration of sLR11 is associated with severity of PH and offers a strong predictor of severe mitral regurgitation in patients after surgery.
Bioakumulasi Merkuri (Hg) pada Lamun Enhalus acoroides dan Mangrove Rhizophora apiculata di Pulau Pari, Kepulauan Seribu
Authors: Simbolon Anna Rejeki , Purbonegoro Triyoni 
Published: December 2021

<strong>Bioaccumulation of Mercury (Hg) in Seagrass <em>Enhalus acoroides</em> and Mangrove <em>Rhizophora apiculata</em> in Pari Island, Seribu Islands. </strong>Heavy metal pollution, especially Hg metal in Jakarta Bay, is feared to have a negative impact on the quality of the waters around the Jakarta Bay waters, one of which is Pari Island in the Thousand Islands. Seagrass and mangroves plants distributed surrounding Pari Island can be used as indicators of heavy metal pollution. The value of bioaccumulation and translocation of Hg metal factors will provide an overview of the ability of plants to accumulate heavy metals in their surroundings. This study aims to determine the bioaccumulation and translocation of the heavy metal Hg factor in <em>Enhalus acoroides</em> seagrass and <em>Rhizophora apiculata</em> mangroves on Pari Island, Seribu Islands. Seagrass and mangrove samples were taken at five sampling points through purposive sampling. The bioaccumulation value was calculated using the ratio of the metal concentrations in each part of the plant body and sediment. Meanwhile, the translocation factor value was calculated by the ratio of Hg concentration in each part of the plant body (roots/rhizomes, stems, and leaves). The results of this study indicate that the bioaccumulation value in seagrass is infinite (bioaccumulation factor, BAF=∞) and in mangroves is 1.57 (BAF&gt;1). The highest <em>translocation factor</em> value in seagrass leaves is 3.86 (translocation factor, TF) &gt;1) and in mangrove leaves is 2.84 (TF&gt;1). This study shows that seagrass and mangrove plants are classified as good bio accumulator and hyperaccumulator plants and accumulate heavy metals, especially Hg in the upper part of their bodies, namely leaves
Situación de las artes escénicas en Argentina en el contexto de Covid-19: acciones de los trabajadores de la danza de Bahía Blanca para mitigar la crisis
Authors: Leonardi Viviana , Tortul Marina , Llera Daniela 
Published: December 2021

En Argentina, gran parte de los trabajadores del arte y cultura, y de la danza en particular, se desempeñan en forma independiente. Esto dejó a este grupo de trabajadores en una situación de especial vulnerabilidad ante las medidas adoptadas para contener la propagación del Covid-19. El objetivo de este trabajo es identificar las dificultades que dicha coyuntura causó a los trabajadores de las artes escénicas y las acciones desplegadas para mitigarlas, haciendo especial hincapié en el caso de los trabajadores de la danza de la ciudad de Bahía Blanca. Para ello se sigue una metodología exploratoria y descriptiva. Se utilizan datos del Sistema de Información Cultural de Argentina (SInCA) para el estudio a nivel nacional y de la Asociación Civil Trabajadores de la Danza en Movimiento de Bahía Blanca (TDM), para el local. Se encuentra que, en ambos ámbitos estos trabajadores pudieron migrar solo parcialmente hacia la modalidad virtual, no sin repercusiones negativas sobre su nivel de ingresos
Los Procesos de Transferencia en la Universidad: Limitaciones, Potencialidades, Desafíos. Una Perspectiva Situada a partir de un Proyecto de Desarrollo Tecnológico y Social en el Marco de la Economía Social y Solidaria
Authors: Vuarant Salomé , Roses Paula Andrea , Herrera Mariela , Perez Daiana 
Published: December 2021

En el presente artículo analizamos los procesos de transferencia tecnológica y social a partir de la experiencia de generación de una marca asociativa, que se llevó a cabo de forma articulada entre la Universidad, un municipio local, el Instituto de Tecnología Industrial, el Club de Emprendedores y con un colectivo de emprendedores/as. Especialmente, nos centramos en indagar sobre las dinámicas que han permitido su funcionamiento; los acuerdos con otros sectores y actores, las relaciones que establece la universidad con la entidad demandante, el funcionamiento del equipo; entre otros.
Nos interrogamos sobre las complejidades de la interacción en la puesta en marcha de acciones a través de una amplia red de agentes e instituciones involucradas que comprende diferentes visiones y concepciones. Para ello, partimos de un análisis situado que entiende a la transferencia como un proceso complejo que no siempre se construye de forma fluida y armónica, que nos permite concluir con las limitaciones y potencialidades de la experiencia.
The Effectiveness of Social Media Facebook and Instagram as Hospital Promotional Media
Authors: Masyitoh Cahyani Dewi , Sumarni Sumarni , Sarwadhamana Raden Jaka 
Published: December 2021

Latar Belakang: Saat ini jumlah rumah sakit di Indonesia terus meningkat dari tahun ke tahun. Banyaknya rumah sakit yang ada serta banyaknya keterlibatan swasta dalam pelayanan kesehatan menjadikan persaingan antara Rumah Sakit juga semakin ketat. Hal ini menuntut Rumah Sakit Pemerintah agar lebih meningkatkan daya saing dan daya tarik pasar sasarannya. Berdasarkan studi pendahuluan ditemukan bahwa kunjungan rawat jalan RSUD Panembahan Senopati Bantul selama tahun 2020 mengalami penurunan pasien dari tahun sebelumnya. Pemasaran online yang saat ini aktif digunakan rumah sakit yaitu melalui media sosial, namun hingga saat ini pihak rumah sakit belum pernah mengukur tingkat efektivitas media sosial yang mereka gunakan sebagai media promosi. Tujuan: Untuk mengetahui adanya perbedaan efektivitas media sosial antara Facebook dengan Instagram sebagai media promosi RSUD Panembahan Senopati Bantul Tahun 2021. Metode Penelitian: Jenis penelitian ini adalah deskriptif kuantitatif dengan rancangan cross sectional. Populasi dalam penelitian ini yaitu pasien rawat jalan yang berkunjung di RSUD Panembahan Senopati Bantul selama satu tahun terakhir berjumlah 146.390. Teknik sampling pada penelitian ini yaitu non-probability sampling dengan jenis sampling kuota. Total sampel berjumlah 100 responden. Analisis data yang digunakan dalam penelitian ini adalah analisis bivariat dengan uji statistik Mann Whitney U-Test. Hasil: Nilai mean pada Facebook adalah sebesar 27.64 dan Instagram sebesar 29.18. Nilai signifikansi Mann Whitney U-Test yaitu sebesar 0.387. Kesimpulan: Tidak terdapat perbedaan yang signifikan pada tingkat efektivitas media sosial antara Facebook dengan Instagram sebagai media promosi RSUD Panembahan Senopati Bantul Tahun 2021.
A Qualitative Study on Nurses’ Experiences of Reporting Patient Safety Incidents in East Nusa Tenggara, Indonesia
Authors: Siga Tage Petrus Kanisius , Berkanis Appolonaris T , Betan Yasinta , Pinis Elisabet Batseba 
Published: December 2021

Background: Reporting patient safety incidents is important to improve patient safety and quality of care. Barriers to report patient safety incidents in nursing may occur due to lack of knowledge and unscheduled as well as low reporting rates. Unfortunately, nurses’ experiences in reporting patient safety incidents have not been comprehensively reviewed.Purpose: The purpose of this study was to explore nurses’ experiences of reporting patient safety incidents in East Nusa Tenggara, Indonesia.Methods: A descriptive phenomenological approach was used to identify, analyze and describe the experiences of 15 nurses in reporting patient safety incidents. Nurses having worked for more than two years, not on leave, not being infected with COVID-19 in the last 14 days, and not having a structural position were purposively recruited. Data were collected using in-depth interviews and voice recordings. The collected data were then transcribed verbatim, and thematic analysis was applied for data analysis.Results: Four main themes were found in this study, which included: (1) Priority and responsibility for services, (2) Barriers to incident reporting, (3) Learning for nurses, and (4) Support for nurses.Conclusion: The nurses experience of in reporting safety incidents is still constrained by several obstacles. It is hoped that health care organizations need to provide appropriate strategies to enhance the safety incident reporting efforts made by nurses. Based on the research findings, it is recommended that health service organizations disseminate the use of safety incident reporting forms and assist nursing managers to their subordinates by conducting supervision and motivation related to incident reporting on a scheduled and continuous basis.
Violence, History and Silence in Amitav Ghosh’s The Shadow Lines
Authors: Gautam Devi Prasad 
Published: December 2021

This article analyzes Amitav Ghosh’s The Shadow Lines to examine a narrative gap at its heart that conceals the central fact of the death of Tridib, arguably the most important character in the text. The novel concentrates on the Partition of Bengal and its impact on people from different countries and nationalities in Asia and Europe. Accommodating the story of three generations of people in three cities--Dhaka, Calcutta, and London--The Shadow Lines shows the interaction of characters belonging to Hindu, Muslim, and Christian faith. Important events in the text revolve around the family of Mayadebi, her sister Tha’mma and the Prices, their English friends. The narrative begins in 1939 and ends in 1964, connecting the Second World War, the Partition in 1947, and the riots of 1964 in Calcutta and Dhaka. Using Tha’mma, the grandmother of the unnamed narrator, as the connecting link between their pre-modern life before Partition in Dhaka and diasporic life in post-Partition Calcutta, The Shadow Lines depicts the traumatic suffering of characters from different nationalities but mainly from India and Bangladesh. The paper argues that the silence and secrecy maintained by Tha’mma and others about Tridib’s death mirrors the silence of official history concerning violence in their narrative of civilization, freedom, and progress which Ghosh unravels to produce a novelistic revisionist history that not only challenges the mainstream history but also fills the gaps it leaves.
ROLA CZYNNIKÓW AFEKTYWNYCH NA PRZYKŁADZIE STREFY KOMFORTU NA ZDALNYCH ZAJĘCIACH JĘZYKOWYCH
Authors: Jankowiak Agnieszka 
Published: December 2021

Affective factors are one of the two types of individual factors that influence success in the process of foreign language learning. They consist of personality traits, as well as positive and negative emotions. This emotional dichotomy is also reflected in the popular concept of comfort zone. The aim of this paper is to define the comfort zone in the context of distance learning language classes and to check if and how it is possible to implement this model in research in the field of glottodidactics. The results of empirical research on the perception and experience of the comfort zone during synchronous distance learning classes by philology students are presented and analyzed in order to draw conclusions on the impact of positive and negative emotions on the process and effects of the language distance learning.
The EU Global Strategy – 5 Years After. The Appropriateness in Face of the Dynamic Strategic Realities
Authors: Śledź Piotr 
Published: December 2021

The objective of the article is to verify to what extent the European Union Global Strategy (EUGS) keeps up with the main global trends (at the level of international order as well as in relation to the global distribution of power) and the processes shaping the EU member states security environment of a regional scale which are perceptible from the perspective of five years following the EUGS adoption. This is also what the main research question concerns – to what extent do the diagnosis and postulates formulated inside the discussed document follow such processes in relation to the 2016–2021 period? For this reason too, the key research approach employed within the study is a critical analysis of source material.
The EU Global Strategy mostly appropriately diagnoses and interprets the realities affecting the member states security – especially when it comes to enduring processes of a global scale regarding the erosion of the liberal international order as well as the roots of possible threats for international security in its military dimension – and formulates the postulates that are pragmatic and detailed. At the same time the document underestimates some of important occurrences or even does not refer to them at all. Examples of such omissions were given in the paper.
The Weimar Triangle: France, Germany, Poland in the Middle East. United Arab Emirates Perspective
Authors: Krzymowski Adam 
Published: December 2021

The article’s scientific goal is to investigate the Weimar Triangle countries’ relations with the United Arab Emirates. Therefore, the author asks the research question. Are the Weimar Triangle states’ role and significance increasing in the external dimension of the European Union? Based on the example of the United Arab Emirates, the research adopted a hypothesis. It is the statement that after Brexit, the Weimar Triangle countries have a chance to improve their importance in the EU external activities. Apart from case studies, to revise the hypothesis, the author performed a meticulous comparative analysis. Moreover, the research implemented International Practice Theory as an appropriate tool to investigate the presented issue. This empirical research and its findings resulted from over ten years of the author’s direct observation, analysis, and participation in many initiatives, both in the European Union and in the United Arab Emirates.
The Middle East for the Weimar Triangle countries is more significant than just from a trade potential perspective. The situation in this region is also affecting Europe, as well as global security architecture. For this reason, one should develop a coherent and comprehensive EU foreign and security policy towards the region, and the Weimar Triangle formula should be one of its pillars.
Analysis of objective quality metrics in computed tomography images affected by metal artifacts
Authors: Rodriguez-Gallo Yakdiel , Orozco-Morales Ruben , Marlen Perez-Diaz  
Published: December 2021

Abstract
Image quality (IQ) assessment plays an important role in the medical world. New methods to evaluate image quality have been developed, but their application in the context of computer tomography is yet limited. In this paper the performance of fifteen well-known full reference (FR) IQ metrics is compared with human judgment using images affected by metal artifacts and processed with metal artifact reduction methods from a phantom. Five region of interest with different sizes were selected. IQ was evaluated by seven experienced radiologists completely blinded to the information. To measure the correlation between FR-IQ, and the score assigned by radiologists non-parametric Spearman rank-order correlation coefficient and Kendall’s Rank-order Correlation coefficient were used; so as root mean square error and the mean absolute error to measure the prediction accuracy. Cohen’s kappa was employed with the purpose of assessing inter-observer agreement. The metrics GMSD, IWMSE, IWPSNR, WSNR and OSS-PSNR were the best ranked. Inter-observer agreement was between 0.596 and 0.954, with p<0.001 in all study. The objective scores predicted by these methods correlate consistently with the subjective evaluations. The application of this metrics will make possible a better evaluation of metal artifact reduction algorithms in future works.
SRPK1 promotes cell proliferation and tumor growth of osteosarcoma through activation of the NF-κB signaling pathway
Authors: Gong Yubao , Yang Chen , Wei Zhengren , Liu Jianguo 
Published: December 2021

Abstract
To explore the expression and the functions of SRPK1 in osteosarcoma, we retrieved transcription profiling dataset by array of human bone specimens from patients with osteosarcoma from ArrayExpress (accession E-MEXP-3628) and from Gene Expression Omnibus (accession GSE16102) and analyzed expression level of SRPK1 and prognostic value in human osteosarcoma. Then we examined the effect of differential SRPK1 expression levels on the progression of osteosarcoma, including cell proliferation, cell cycle, apoptosis, and investigated its underlying molecular mechanism using in vitro osteosarcoma cell lines and in vivo nude mouse xenograft models. High expression level of SRPK1 was found in human osteosarcoma tissues and cell lines as compared to the normal bone tissues and osteoblast cells, and predicted poor prognosis of human osteosarcoma. Overexpression of SRPK1 in osteosarcoma U2OS cells led to cell proliferation but inhibition of apoptosis. In contrast, knockdown of SRPK1 in HOS cells impeded cell viability and induction of apoptosis. Moreover, silencing SRPK1 inhibited osteosarcoma tumor growth in nude mice. Mechanistic studies revealed that SRPK1 promoted cell cycle transition in osteosarcoma cells and activation of NF-κB is required for SRPK1 expression and its pro-survival signaling. SRPK1 promoted human osteosarcoma cell proliferation and tumor growth by regulating NF-κB signaling pathway.