bluuebunny/crossref_metadata_2025_split huggingface dataset:
Symptomatology in cases of vaginal cuff prolapse
Authors: TUĞRUL ERSAK Duygu , DOĞANAY Melike 
Published: November 2021

Aim: To define the admission symptoms and complaints of cases with vaginal cuff prolapse
Materials and Methods: A retrospective study between January 2019 – 2021 including 34 patients admitted to University of Health Science Turkey with the diagnosis of vaginal cuff prolapse. While patients who had grade < 3 vaginal cuff prolapse were accepted as early stage prolapse, patients with grade ≥ 3 vaginal cuff prolapse were accepted as advanced stage prolapse. Patients’ initial clinical symptoms and complaints at the time of admission were recorded.
Results: The most common symptom in patients with vaginal cuff prolapse was pressure sensation in the vagina. Fecal incontinence was the least reported symptom. The prolapse symptom were higher in the advanced staged cuff prolapse group than in the early stage group (p
Understanding the Effects of Systematics in Exoplanetary Atmospheric Retrievals
Authors: Ih Jegug , Kempton Eliza M.-R. 
Published: November 2021

Abstract
Retrieval of exoplanetary atmospheric properties from their transmission spectra commonly assumes that the errors in the data are Gaussian and independent. However, non-Gaussian noise can occur due to instrumental or stellar systematics and the merging of discrete data sets. We investigate the effect of correlated noise and constrain the potential biases incurred in the retrieved posteriors. We simulate multiple noise instances of synthetic data and perform retrievals to obtain statistics of the goodness of retrieval for varying noise models. We find that correlated noise allows for overfitting the spectrum, thereby yielding a better goodness of fit on average but degrading the overall accuracy of retrievals. In particular, correlated noise can manifest as an apparent non-Rayleigh slope in the optical range, leading to an incorrect estimate of cloud/haze parameters. We also find that higher precision causes correlated results to be further off from the input values in terms of estimated errors. Finally, we show that while correlated noise cannot be reliably distinguished with Hubble Space Telescope observations, inferring its presence and strength may be possible with James Webb Space Telescope observations. As such, we emphasize that caution must be taken in analyzing retrieved posteriors and that estimated parameter uncertainties are best understood as lower limits.
A 99 minute Double-lined White Dwarf Binary from SDSS-V
Authors: Chandra Vedant , Hwang Hsiang-Chih , Zakamska Nadia L. , Gänsicke Boris T. , Hermes J. J. , Schwope Axel , Badenes Carles , Tovmassian Gagik , Bauer Evan B. , Maoz Dan , Schreiber Matthias R. , Toloza Odette F. , Inight Keith P. , Rix Hans-Walter , Brown Warren R. 
Published: November 2021

Abstract
We report the discovery of SDSS J133725.26+395237.7 (hereafter SDSS J1337+3952), a double-lined white dwarf (WD+WD) binary identified in early data from the fifth-generation Sloan Digital Sky Survey (SDSS-V). The double-lined nature of the system enables us to fully determine its orbital and stellar parameters with follow-up Gemini spectroscopy and Swift UVOT ultraviolet fluxes. The system is nearby (d = 113 pc), and consists of a 0.51 M
⊙ primary and a 0.32 M
⊙ secondary. SDSS J1337+3952 is a powerful source of gravitational waves in the millihertz regime, and will be detectable by future space-based interferometers. Due to this gravitational wave emission, the binary orbit will shrink down to the point of interaction in ≈220 Myr. The inferred stellar masses indicate that SDSS J1337+3952 will likely not explode as a Type Ia supernova (SN Ia). Instead, the system will probably merge and evolve into a rapidly rotating helium star and could produce an underluminous thermonuclear supernova along the way. The continuing search for similar systems in SDSS-V will grow the statistical sample of double-degenerate binaries across parameter space, constraining models of binary evolution and SNe Ia.
Panspermia in a Milky Way–like Galaxy
Authors: Gobat Raphael , Hong 홍 Sungwook E. 성욱 , Snaith Owain , Hong 홍 Sungryong 성용 
Published: November 2021

Abstract
We study the process of panspermia in Milky Way–like galaxies by modeling the probability of successful travel of organic compounds between stars harboring potentially habitable planets. To this end, we apply the modified habitability recipe of Gobat & Hong to a model galaxy from the McMaster Unbiased Galaxy Simulations suite of zoom-in cosmological simulations. We find that, unlike habitability, which only occupies a narrow dynamic range over the entire galaxy, the panspermia probability can vary by orders of magnitude between the inner (R, b = 1–4 kpc) and outer disk. However, only a small fraction of star particles have very large values for the panspermia probability and, consequently, the fraction of star particles where the panspermia process is more effective than prebiotic evolution is much lower than from naïve expectations based on the ratio between the panspermia probability and natural habitability.
Vulnerability of the Brazilian LGBT population in HIV treatment
Authors: Lourenção Tauyr Thaisa Fernanda , Garcia Lourenção Luciano , Zanon Ponce Maria Amélia , Guimarães Ximenes Neto Francisco Rosemiro , Sperli Geraldes Santos Maria de Lourdes , Sperli Geraldes Marin dos Santos Sasaki Natália , Figueiredo Vendramini Silvia Helena 
Published: November 2021

Introduction: Human immunodeficiency virus (HIV) infection affects the lesbian, gay, bisexual, transvestite, and transsexual (LGBT) population. We aimed to identify the indidual vulnerability profile of the LGBT population ling with H/acquired immunodeficiency syndrome (AIDS) and correlate it with the treatment situation.
Methodology: This cross-sectional study included 510 LGBT people living with HIV (PLHIV)/AIDS who attended the Complex of Chronic Communicable Diseases of the municipality of São José do Rio Preto, São Paulo, Brazil, between 2008 and 2015.
Results: There was a predominance of indiduals who were white (70.2%), male (98.4%), single (87.1%), aged 25–44 years (70.0%), educated up to high school (47.7%), economically acte (91.2%), under treatment (80.8%), having CD4 > 350 cells/mm3 (77.1%), and having undetectable viral load (53.3%). HIV transmission was mainly sexual (97.0%) and most people used drugs (76.5%). There was a weak correlation between the variables ‘in treatment’ and acte occupation (r = 0.148, p = 0.001), single marital status (r = 0.128, p = 0.004), white race/colour (r = 0.117, p = 0.008), high school education (r = 0.111, p = 0.012), sexual transmission (r = 0.222, p = 0.000), drug use (r = 0.087, p = 0.049), and CD4 > 350 cells/mm3 (r = 0.118, p = 0.008); and strong correlation between the variables ‘in treatment’ and undetectable viral load (r = -0.937, p = 0.113).
Conclusions: The characteristics of the indidual vulnerability of LGBT people involve, among other aspects, issues of gender and social exclusion, a situation that is part of the daily life of PLHIV/AIDS in many scenarios and territories. This can be alleviated with a network of social and health support and effecte and efficient, protecte, attitudinal, and behavioural public policies.
Association between obesity and diabetes prevalence and COVID-19 mortality in Mexico: an ecological study
Authors: Noyola Daniel Ernesto , Hermosillo-Arredondo Natalia , Ramírez-Juárez Carolina , Werge-Sánchez Annia 
Published: November 2021

Introduction: Mortality rates associated with COVID-19 vary widely between countries and, within countries, between regions. These differences might be explained by population susceptibility, environmental factors, transmission dynamics, containment strategies, and diagnostic approaches. We aimed to analyze if obesity and diabetes prevalence are associated with higher COVID-19 mortality rates in Mexico.
Methodology: We analyzed the mortality rate for each of the 2,457 municipalities in Mexico, one of the countries with highest COVID-19 mortality rate, during the first seven months of the pandemic to identify factors associated with higher mortality, including demographic, health-related characteristics (prevalence of obesity, diabetes, and hypertension in adults older than 20 years old), and altitude.
Results: During the first seven months of the COVID-19 pandemic there were 85,666 deaths reported in Mexico, with a cumulative mortality rate of 67 per 100,000 population. The mean mortality rate for the 2,457 municipalities in Mexico was 33.9 per 100,000 population. At a municipal level, the prevalence of diabetes and obesity, as well as high human development index, and location at < 500 or > 2000 above sea level were associated with higher mortality rate.
Conclusions: Elevated obesity and diabetes prevalence explain, in part, high COVID-19 mortality rates registered in certain municipalities in Mexico. These results suggest that a regionalized approach should be considered to successfully limit the impact of SARS-CoV-2.
Manuel de soins palliatifs
Authors: Belloir Marie-Noëlle 
Published: November 2021

Résumé Le patient doit être pris en charge là où il se trouve et le soignant est en capacité de l'accompagner. Est-ce que l'offre répond aux besoins ? La démarche palliative, met l'accent sur plusieurs points : prendre soin, redonner du sens aux actes de soins, travailler sur ses propres représentations de la mort, de l'accompagnement, travailler en interdisciplinarité, mais la question est surtout d'« Oser être là ». La question de l'USP est celle de l'équité : ceux qui en bénéficient seraient des privilégiés ? La question des LISP est d'intégrer au projet de service une mission d'accompagnement et de la faire vivre. La question de l'EMSP est celle de la non-substitution (pour ne pas faire à la place – pertinence de l'enseignement).
Les enjeux de la communication sur la tuberculose en Côte d’Ivoire
Authors: Seytre Bernard , Amalaman Djedou Martin , Diaby Moustapha , Sansan Kambou Édouard , Coulibaly Madiarra , Yoro Blé 
Published: November 2021

Introduction : La tuberculose se présente comme un phénomène social total qui implique les dimensions économiques et socioculturelles des personnes infectées et des acteurs institutionnels de lutte contre le fléau. En Côte d’Ivoire, où seulement 59 % des cas estimés ont été notifiés et traités en 2018, le sous-diagnostic constitue l’un des principaux obstacles à la lutte contre la tuberculose. Objectif : L’objectif de cette étude socioanthropologique était de fournir des bases à des recommandations de communication susceptibles d’accroître la demande de dépistage de la tuberculose en Côte d’Ivoire. Elle a donc porté sur les représentations de la tuberculose susceptibles d’être influencées par les campagnes de communication. Méthode : Elle a mobilisé, d’une part, une approche qualitative à travers des entretiens semi-directifs auprès de 54 personnes et 28 focus groups de 8 personnes chacun et, d’autre part, une approche quantitative auprès de 400 personnes soumises à un questionnaire. L’étude s’est déroulée à Abidjan, Bouaké, Korhogo et San-Pédro, en Côte d’Ivoire. Résultats : Les résultats ont montré, entre autres, que la population a une très bonne connaissance de l’existence et de la gravité de la tuberculose, une bonne connaissance de ses symptômes, qu’elle fait peu confiance à la médecine traditionnelle en cas de tuberculose et qu’elle sait que la maladie peut être traitée par les médicaments de la médecine moderne. En revanche, la moitié de la population seulement sait que le traitement est gratuit, ce qui peut tenir des malades éloignés des structures sanitaires. Les enquêtés associent très majoritairement la tuberculose à l’infection à VIH et au sida. La peur suscitée par cette association est susceptible d’être un frein important à l’entrée dans une démarche thérapeutique en cas de suspicion de tuberculose. Conclusion : Il nous paraît donc nécessaire de renforcer la communication sur la gratuité du traitement contre la tuberculose et de dissocier tuberculose et VIH dans les outils de communication et de sensibilisation à la tuberculose comme au VIH.
Clinical, biochemical and imaging characteristics of adrenal histoplasmosis in immunocompetent patients in a non-endemic area
Authors: Jahan Sharmin , Mahmood Tahseen , Fariduddin Md , Faisal Ibrahim , Morshed Md Shahed , Yadav Anil , Shah Anil Kumar , Abdullah Chomon , Chowdhury Emran-Ur-Rashid , Begum Ferdousi , Hasanat M A 
Published: November 2021

Objective:
To document the clinical, biochemical and imaging phenotypes of immunocompetent patients with adrenal histoplasmosis.

Methods:
The clinical, biochemical and radiologic data of 18 immunocompetent patients [age: 45.00 (39.25, 56.25) years, median (IQR), m/f (16/2)] with adrenal histoplasmosis presenting in the Department of Endocrinology, BSMMU between 2014 and 2020 were retrospectively analyzed.

Results:
All patients were seronegative for HIV infection, and 27.8% (5/18) had well controlled diabetes mellitus. The median duration of the symptoms was 6.00 (IQR: 4.00, 11.25) months. All had significant weight loss, anorexia and weakness. Fever was present in 61.1% (11/18) patients and night sweat was present in 27.8% (5/18) cases. Hypotension and hyperpigmentation were present in 55.6% (10/18) and 66.7% (12/18) cases, respectively. Three of 18 patients presented with adrenal crisis. Hyponatremia occurred in 55.6% (10/18) cases, but none had hyperkalemia. Thirteen of 18 patients had adrenal insufficiency whereas 83.3% (15/18) had high adrenocorticotropic hormone. CT scan revealed bilateral adrenal enlargement in all cases with oval shape and regular margin. All were hypodense having radiodensity 21-90 hounsfield unit, and 11.1% (2/18) were heterogeneous in contrast enhancement. None had noticeable calcification whereas 1.1% (2/18) cases had central necrosis with peripheral rim enhancement. Hepatomegaly was present in 6 cases, splenomegaly in 3 cases and 5 patients had abdominal lymphadenopathy. Histoplasmosis were confirmed by positive fine needle aspiration cytology of adrenal tissue.

Conclusions:
Adrenal histoplasmosis should be considered in the list of differentials of bilateral adrenomegaly in immunocompetent individuals even living in non-endemic areas.
Detection of dengue virus serotype 3 in Cajamarca, Peru
Authors: Aguilar-Luis Miguel Angel , Carrillo-Ng Hugo , Kym Sungmin , Silva-Caso Wilmer , Verne Eduardo , del Valle Luis J. , Bazán-Mayra Jorge , Zavaleta-Gavidia Victor , Cornejo-Pacherres Daniel , Tarazona-Castro Yordi , Aquino-Ortega Ronald , Cornejo-Tapia Angela , del Valle-Mendoza Juana 
Published: November 2021

Objective:
To describe and molecularly characterize an outbreak of dengue virus (DENV) infection in Cajamarca, an Andean region in Peru.

Methods:
A total of 359 serum samples from patients with acute febrile illness were assessed for the presence of DENV via RT-PCR, ELISA NS1, IgM and IgG in Cajamarca, Peru from January 2017 to June 2017. The evaluation of the different diagnostic tests and their applicability was performed.

Results:
Dengue virus was detected in 24.7% of samples by RT-PCR. Meanwhile, serological analysis detected 30.3% positive cases via ELISA NS1 antigen, 16.7% via ELISA IgG and 9.7% via ELISA IgM. Most of the cases corresponded to DENV-3 (77.5%). The use of RT-PCR performed better in primary infections (P<0.01), while detection of ELISA IgM performed better in secondary infections (P<0.01). The combination of NS1 and IgM performed better than the other assays in detecting primary (92.5%) and secondary infections (96.6%). The most frequent symptoms associated with fever were headaches, myalgias, and arthralgias across all groups.

Conclusions:
We report an important outbreak of dengue infection caused by DENV-3 in Cajamarca, Peru. Our findings encourage the use of NS1 antigen and IgM co-detection. These findings demonstrate an increasing expansion of DENV-3 in Peru and highlight the importance of molecular diagnosis and serotype characterization among the clinically defined dengue cases to strengthen the Peruvian epidemiological surveillance.
Prevalence of non-tuberculosis mycobacteria among samples deposited from the National Tuberculous Reference Laboratory of Iran (2011-2018)
Authors: Ayoubi Saman , Farnia Parissa , Farnia Poopak , Aghajani Jafar , Ghanavi Jalaledin , Velayati Ali Akbar 
Published: November 2021

Objective:
To investigate the prevalence of non-tuberculosis mycobacteria (NTM) among the samples deposited from the National Tuberculosis Reference Laboratory of Iran between 2011 and 2018.

Methods:
The study evaluated the prevalence of NTM among specimens from patients with pulmonary tuberculosis symptoms (n=15 771) deposited at the National Tuberculosis Reference Laboratory of Iran from 2011 to 2018. Detection of Mycobacterium (M.) tuberculosis was based on presence of a 190-bp amplicon from IS6110 insertion sequence using Tb1 and Tb2 primers, and amplicon-negative specimens were tested for NTM and M. tuberculosis (refractory to IS6110 amplification) using restriction fragment length polymorphism PCR of hsp65 amplicon fragment.

Results:
A total of 7 307 (46.33%) M. tuberculosis and 658 (4.17%) NTM specimens were found, the latter mainly comprising M. abscessus (10.18%), M. avium (2.28%), M. chelonae (8.97%), M. intracellulare (10.49%), M. kansasii (4.71%), and M. simiae (56.08%).

Conclusions:
As treatment for NTM differs from that for M. tuberculosis, accurate detection of Mycobacterium sp. is of public health significance.
Use of Inferior Venacaval Collapsibility Index in Spinal Anesthesia during Orthopedic Surgeries
Authors: Devi K. Poolan , Doddamane K. Poonam , Manjunath H. G , Murdeshwar Greeshma N. 
Published: November 2021

Background:
Volume deficit is one of the predictors of hypotension. Inferior venacaval collapsibility index (IVCCI) can detect volume deficit and aids volume resuscitation in patients of intensive care unit.

Aims:
The primary aim was to compare the incidence of postspinal anesthesia hypotension (PSAH) in IVCCI measured and nonmeasured groups. The secondary aim was to determine IVCCI association with PSAH within IVCCI measured group in spite of fluid bolus.

Settings and Designs:
This was a prospective, randomized, controlled, single-blinded study.

Methodology:
One hundred patients posted for orthopedic surgery under spinal anesthesia (SA) were randomly divided as IVCCI measured (CI) and non-IVCCI measured (NCI) groups before SA. If IVCCI was more than 40% fluid bolus was given. Intraoperative hemodynamics was monitored. PSAH managed with fluids and vasopressors which were noted. Data collected were analyzed with unpaired t-test, Z-test, logistic regression test, and Pearson's correlation.

Results:
PSAH incidence was 18% in group (CI) whereas 38% in group (NCI), and the difference was statistically significant. Vasopressors given were higher in group NCI. Perioperative fluids were more in group CI, but the intraoperative fluids were more in group NCI. There was no statistically significant association between PSAH after fluid preloading and IVCCI within the IVCCI measured group.

Conclusion:
Prespinal anesthesia evaluation of IVCCI to optimize fluid therapy can reduce the incidence of PSAH in orthopedic surgeries and the vasopressor requirement, and hence, the association of IVCCI of more than 40% with PSAH.
An Observational Study of Hemostatic Profile during Different Stages of Liver Transplant Surgery Using Laboratory-Based Tests and Thromboelastography
Authors: Bansal Shweta , Garg Ankur , Khatuja Amit , Ray Ramdip , Bora Giriraj 
Published: November 2021

Background:
Liver produces most of the blood coagulation factors, so it is not surprising to see a deranged coagulation profile in patients receiving liver transplants. Besides standard laboratory methods to evaluate coagulation profile, point-of-care assays are being used regularly since their results are rapidly available. However, sparse information is available on the comparability of point-of-care coagulation assays with laboratory coagulation assays in this special setting. In this study, our aim is to observe the changing hemostatic profile during different stages of liver transplant surgery using laboratory-based tests and thromboelastography (TEG).

Methods:
Fifty patients undergoing living donor liver transplantation surgery were selected. Coagulation tests (prothrombin time [PT], activated partial thromboplastin time [APTT], platelet count, and fibrinogen) and TEG were performed at various intervals during liver transplant surgeries – before induction of anesthesia, 2 h into dissection phase, 30 min into anhepatic phase, 30 min after reperfusion of homograft, postoperative – at closure of surgery, 12 h postoperative, and 24 h postoperative. Statistical analysis and Pearson correlation were performed between laboratory-based coagulation tests and TEG, and their pattern through various stages of the surgery analyzed.

Results:
Platelet count and fibrinogen have a significant positive correlation with TEG in almost all phases of liver transplant. PT and APTT have a positive correlation with TEG until uptake of new liver and predominantly negative correlation after that. However, this correlation is significant only before induction of anesthesia and anhepatic phase.

Conclusions:
TEG can be used to estimate platelet count and fibrinogen concentrations in all phases but PT and APTT only before induction and anhepatic phase of liver transplant surgery. The decision regarding transfusion of blood products should be based on a combination of the clinical assessment of surgeon and anesthesia personnel combined with results from laboratory and TEG.
Quadratus Lumborum Block for Patients Undergoing Percutaneous Nephrolithotomy
Authors: Raman Rajesh , Prabha Rati 
Published: November 2021

Background:
Recent studies have supported the use of quadratus lumborum block (QLB) for postoperative analgesia for patients undergoing renal surgery.

Aims:
The aim was to study the efficacy of posterior QLB for postoperative analgesia in patients undergoing percutaneous nephrolithotomy (PCNL).

Settings and Design:
This trial was a hospital-based, randomized, double-blind, controlled, prospective study.

Materials and Methods:
Forty patients aged from 18 to 60 years, belonging to the American Society of Anesthesiologists physical status I–III and scheduled for unilateral PCNL under spinal anesthesia were administered ultrasound-guided posterior QLB with 30 ml of either 0.2% ropivacaine (Group Q) or normal saline (Group C) after the subarachnoid block. Duration of analgesia was the primary outcome variable.

Statistical Analysis Used:
Data were compiled in Microsoft Excel, and analyses were performed in SPSS (version 24.0.0.0; IBM, Armonk, New York, USA). Unpaired t-test, Mann–Whitney U test, and Fisher's exact test were used for the comparison of continuous, ordinal, and categorical data, respectively.

Results:
Duration of analgesia was significantly longer in Group Q (1167.10 ± 89.74 vs. 290.25 ± 47.38 min), as compared to Group C. Except at the end of the surgery, visual analog scale at rest and on movement was significantly lower till 20th h in Group Q. Patient satisfaction was better, and analgesic consumption was lower in Group Q. Side effects were similar in both groups.

Conclusions:
QLB provides good quality, and prolonged duration of postoperative analgesia compared to placebo for PCNL, but more large-scale studies are needed to recommend it for routine use.