bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Effectiveness of Training for Awareness Resilience and Action Online Compared to Standard Treatment for Adolescents and Young Adults With Depression: Study Protocol and Analysis Plan for a Pragmatic, Multi-Center Randomized Controlled Superiority Trial
Authors: Ekbäck Erik , Granåsen Gabriel , Svärling Rachel , Blomqvist Ida , Henje Eva 
Published: October 2021

Depression in adolescents and young adults is an increasing global health concern. Available treatments are not sufficiently effective and relapse rates remain high. The novel group-treatment program “Training for Awareness, Resilience and Action” (TARA) targets specific mechanisms based on neuroscientific findings in adolescent depression. TARA is framed within the National Institute of Mental Health's Research Domain Criteria and has documented feasibility and preliminary efficacy in the treatment of adolescent depression. Since neurodevelopment continues well into the mid-twenties, age-adapted treatments are warranted also for young adults. Patients 15–22 years old, with either major depressive disorder (MDD) or persistent depressive disorder (PDD) according to the DSM-IV/5 or a rating &gt;40 on the clinician rating scale Children's Depression Rating Scale—Revised (CDRS-R), will be recruited from specialized Child and Adolescent Psychiatry and local Youth-Clinics and randomized to either TARA or standard treatment, including but not limited to antidepressant medication and/or psychotherapy. Outcome measures will be obtained before randomization (T0), after 3 months of treatment (T1) and at 6-months- (T2) and 24-months- (T3) follow-up. Additionally, dose-response measures will be obtained weekly in the TARA-arm and measures for mediation-analysis will be obtained halfway through treatment (T0.5). Primary outcome measure is Reynolds Adolescent Depression Scale (RADS-2) score at T1. Secondary outcome measures include RADS-2 score at T2, Multidimensional Anxiety Scale for Children at T1 and T2, and CDRS-R at T1. Additional outcome measures include self-report measures of depression-associated symptoms, systemic bio-indicators of depression from blood and hair, heartrate variability, brain magnetic resonance imaging, as well as three-axial accelerometry for sleep-objectivization. Qualitative data will be gathered to reach a more comprehensive understanding of the factors affecting adolescents and young adults with depression and the extent to which the different treatments address these factors. In summary, this article describes the design, methods and statistical analysis plan for pragmatically evaluating the clinical effectiveness of TARA. This will be the first RCT to examine the effects of TARA compared to standard treatment for adolescents and young adults with MDD or PDD. We argue that this study will extend the current knowledgebase regarding the treatment of depression.NCT Registration: identifier [NCT04747340].
Secreted Secondary Metabolites Reduce Bacterial Wilt Severity of Tomato in Bacterial–Fungal Co-Infections
Authors: Venkatesh Nandhitha , Koss Max J. , Greco Claudio , Nickles Grant , Wiemann Philipp , Keller Nancy P. 
Published: October 2021

In order to gain a comprehensive understanding of plant disease in natural and agricultural ecosystems, it is essential to examine plant disease in multi-pathogen–host systems. Ralstonia solanacearum and Fusarium oxysporum f. sp. lycopersici are vascular wilt pathogens that can result in heavy yield losses in susceptible hosts such as tomato. Although both pathogens occupy the xylem, the costs of mixed infections on wilt disease are unknown. Here, we characterize the consequences of co-infection with R. solanacearum and F. oxysporum using tomato as the model host. Our results demonstrate that bacterial wilt severity is reduced in co-infections, that bikaverin synthesis by Fusarium contributes to bacterial wilt reduction, and that the arrival time of each microbe at the infection court is important in driving the severity of wilt disease. Further, analysis of the co-infection root secretome identified previously uncharacterized secreted metabolites that reduce R. solanacearum growth in vitro and provide protection to tomato seedlings against bacterial wilt disease. Taken together, these results highlight the need to understand the consequences of mixed infections in plant disease.
Effect of Percussion and Postural Drainage Positions on Cardiovascular and Respiratory Parameters
Authors: Onigbinde Ayodele Teslim , Adedoyin Rufus A , Orijajogun O O , Uloko A E 
Published: October 2021

Background of the study: There are different drainage positions for different lobes of the lungs but most studies on the effect of postural drainage and percussion on cardiovascular and cardiorespiratory are old and also inconclusive.
Aims: The primary aim of this study was to determine the effect of postural drainage positions and percussion in prone lying with foot of bed raised to 45cm and right side lying with 45 degree turn on to the face on cardiovascular and cardiorespiratory parameters such as systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (RR) and respiratory rate (RR).
Method: Forty subjects (20 males and females each) participated in the study and they were randomly assigned to 4 groups with 10 participants in each group. The cardiovascular and cardiorespiratory parameters were measured at sitting (pre-positioning), mid and postpositioning after 15 minutes. The data was analysed using descriptive and inferential statistic.
Results: The results showed that percussion significantly decreased the systolic blood pressure (F = 3.15; P < 0.05) while the respiratory rate was increased significantly (F= 5.40; p < 0.05) when the subjects were in prone lying position. The result also showed that the systolic blood pressure and the respiratory rate increased significantly (F=I.26; p < 0.05) and (F=7.18; p
EFL Students’ Perceptions and Attitudes toward Using Communicative Activities in CLT Classroom
Authors: Rezalou Ali , Yagiz Oktay 
Published: October 2021

In this study, the effects of using the communicative activities in communicative language teaching (CLT) classroom to improve students’ speaking performance and reduce their difficulties in speaking skill were investigated. Classroom action research (CAR) was considered as the research design. A quantitative method was followed in this study. The researcher intended to improve the students’ speaking ability by using the Communicative Language Teaching Method, communicative activities. The teaching and learning process was divided into ten cycles and was carried out in ten weeks. Each cycle consisted of four interconnected stages: Planning, Action, Observation, and Reflection. Overall, students favored activities that provided a competitive classroom environment and led to a high level of classroom participation. The findings revealed the effectiveness of speaking classes because students were significantly more satisfied with their speaking ability after the interventions. Statistically significant differences were found in students’ perceptions and attitudes toward using communicative activities.
The Research Output of Bibliometrics using Bibliometrix R Package and VOS Viewer
Authors: Radha L , Arumugam J 
Published: October 2021

Bibliometrics is one of the statistical methods to analyze the research output of books, articles, and other scientific publications. This paper attempts to study the three types of Bibliometric indicators such as quantity, quality, and structural indicators. This study pertains to the information on the research growth of Bibliometric study, especially in the subject category of Library and Information Science published in Web of Science Database. This paper presents the findings of a Bibliometric study, targeting five year period (2014–2018), with the aim of identifying emerging research directions, the top-20 institutions, coupling, and collaboration by applying VOS viewer and Biblioshiny for bibliometric tools.
PENGEMBANGAN MEDIA E-LEARNING BERBASIS MOODLE SEBAGAI SUPLEMEN PEMBELAJARAN GEOGRAFI PADA MATERI MITIGASI BENCANA ALAM
Authors: Mariezki Raffi , Juita Erna , Tanamir Momon Dt 
Published: October 2021

This study aims to analyze the feasibility and practicality of moodle-based e-learning as supplement to learning geography in natural disaster mitigation materials. This type of research is research and development of the four d model, namely: Define, Design, Development, Desiminate. The research subjects of SMA N 3 Padang class XI IPS. Moodle-based e-learning development includes validation of media, education and language experts. The validation data were processed using the interclass correlation coefficient and the results obtained were 0.957. If the value is more than 0.5, it can be concluded that the level of validation is adequate. Measurement of the feasibility of the media is obtained from data processing using Microsoft Excel so that a total score of 282 is obtained with a mean of 4.90 and a percentage of 98% with a very good predicate. The practicality test of moodle-based e-learning media was based on questionnaire data and obtained a total score of 4077 with a mean of 4.1 and a percentage of 82% with the very practical category.
Problems of the reliability of water supply and wastewater disposal systems, and ways of solution
Authors: Степанов М.А. , Примин О.Г. 
Published: October 2021

Надежность и экологическая безопасность являются основными требованиями, предъявляемыми к системам водоснабжения и водоотведения. Трубопроводные системы – неотъемлемая часть инфраструктуры современных городов. Нарушения нормального уровня работы этих систем связаны в основном с авариями (отказами) на участках трубопроводов – наиболее функционально значимых, дорогостоящих и уязвимых элементов систем. Нарастающие темпы износа и неудовлетворительное техническое состояние значительного количества трубопроводов водоснабжения и водоотведения большинства городов и поселений России, ограничение в условиях реформирования жилищно-коммунального хозяйства России материальных ресурсов на их восстановление и обновление требуют научно обоснованного подхода к решению проблемы оценки и обеспечения их надежности. Отмечено, что до настоящего времени в отечественной практике накопление и использование статистических материалов, необходимых для определения показателей надежности элементов систем водоснабжения и водоотведения, а также планирование их восстановления организованы неудовлетворительно. Приведены методы оценки надежности трубопроводов, методика планирования их восстановления с использованием компъютерной программы, критерии выбора объектов восстановления трубопроводов и пути повышения их надежности.
Reliability and environmental safety are the main requirements for water supply and wastewater disposal systems. Pipeline systems are an integral part of the infrastructure of modern cities. Malfunctions of these systems are mainly associated with failures in pipeline sections, that are the most functionally significant, expensive and vulnerable elements of the systems. The increasing rates of wear and unsatisfactory technical condition of a significant number of water pipelines and sewers in most cities and communities of Russia, the limited material resources for their rehabilitation and renovation in the context of reforming the housing services and public utilities of Russia require a scientifically based approach to solving the problem of assessing and ensuring their reliability. It is noted that up to now, in domestic practice, the accumulation and use of statistics for determining the reliability indicators of the elements of water supply and wastewater disposal systems, as well as planning their rehabilitation, have been arranged unsatisfactorily. Methods for assessing the reliability of pipelines, a methodology for planning their rehabilitation using a software application, criteria for selecting objects for pipeline renovation and ways to improve their reliability are presented.
O farmacêutico clí­nico e os custos com antimicrobianos: um estudo em uma unidade de terapia intensiva
Authors: Amorim da Silva Letí­cia , Godoi da Silva Rianne Kercia , Morais da Silva Thais , Ivonete dos Santos Jucélia , Guedes Silveira Cabral Analúcia 
Published: October 2021

Objetivo: Avaliar a importância do farmacêutico clí­nico tanto na utilização dos antimicrobianos, quanto na redução de custo desses medicamentos.Método: O estudo caracterizado como descritivo, com abordagem quantitativa foi realizado no perí­odo de outubro a dezembro de 2016 em uma Unidade de Terapia Intensiva de um hospital público na cidade de Caruaru-PE. A coleta de dado ocorreu por meio de análise documental utilizando como ferramenta o sistema operacional padrão MV200.Resultados: Verificou-se uma maior utilização de piperacilina+tazobactam e meropenem, ambos antibióticos com amplo espectro de ação, evidenciando a escolha de terapias por parte dos protocolos do hospital com essa caracterí­stica. Entretanto, não se observa uma redução de gastos significativos em decorrência de um alto consumo ainda prevalente de antimicrobianos por pacientes de UTI. Conclusão: Diante dos resultados, infere-se que a ação de um farmacêutico clí­nico na Unidade de Terapia Intensiva auxiliaria com um maior controle dessas prescrições, evitando interações medicamentosas e atendendo í s necessidades de cada paciente.
THE QUESTION OF THE PERIODIZATION OF THE GENESIS OF THE SOCIAL STATE
Authors: Чупилкина Айгуль Фаридовна 
Published: October 2021

Автор формулирует предложение для научного дискурса по поводу чрезвычайно актуального и необходимого для Российского государства феномена социального государства. Поднят вопрос единого представления о генезисе социального государства и его критериях. Исторические примеры, в которых показаны реализация и последствия социальных законов в различной государственной и общественной «почве», помогают определить место и разумное применение элементов социального государства в современной российской государственности. Жизнеспособные элементы для распределения этапов эволюции социального государства имеют аргументы различных авторов. На основании проведенного анализа четкость критериев периодизации генезиса социального государства предложено обозначить как совокупность (систему) признаков, перечисленных в настоящей статье. Сформулированная совокупность (система) признаков позволила утверждать, что зародилось социальное государство в эпоху Античной Греции. Более того, древнегреческая мысль в принципе оказала влияние на юридическое мировоззрение прошлого, настоящего и будущего. Здесь впервые использованы основные понятия теории государства и права, что на сегодняшний день является основой теоретических знаний правоведа. Уголовно-исполнительная система является социальным институтом, что обусловливает важность трактовки тематики истории и теории социального государства.
The author formulates a proposal for scientific discourse, due to the unsolved, but extremely relevant and necessary for the Russian state, the phenomenon of the social state. The question of a unified idea of the genesis of the social state and its criteria is raised. Illustrative historical examples in which are the implementation and consequences of social laws help to determine the place and reasonable application of the elements of the social state in modern Russian statehood. The arguments of various authors have viable elements for the distribution of the stages of the evolution of the social state. Based on the analysis, the clarity of the criteria for the periodization of the genesis of the social state is proposed to be designated as a set (system) of the features listed in this article. The formulated set (system) of features allowed us to assert that the origins of the social state have their roots in the era of Ancient Greece. In addition, ancient Greek thought in principle influenced the legal worldview of the past, present and future. Here, for the first time, the basic concepts of the theory of state and law are used, which today is the basis of the theoretical knowledge of a jurist. The penal system is a social institution, which determines the importance of interpreting the topics of history and the theory of the social state.
Proses Bleach Washing pada Kain Denim yang Dicelup dengan Zat Warna Indigo Menggunakan Natrium Hipochlorit (NaOCl)
Authors: Luciana Luciana , Koesneliwati Elly 
Published: October 2021

The process of bleach washing on denim fabrics produces a paler or lighter shabby effect. The shabby effect is produced by using an oxidizing agent. The application of sodium hypochlorite can cause a decrease in color aging of denim fabrics and high tensile strength. The pH condition also affects the occurrence of oxycellulose damage which will affect the final result. Inappropriate pH will cause a very high oxidation process and produce a less shabby effect and can cause a decrease in tensile strength. Therefore, the concentration of NaOCl and pH must be adjusted properly so that optimal results are obtained. The purpose of this study was to determine the effect of optimum concentration of sodium hypochorite (NaOCl) and pH on the physical properties of denim fabric. After the process of bleach washing process experiment was carried out, a test was carried out based on two-factor Anova statistical data and the optimum visual test fabric results were obtained at a NaOCl concentration of 2 g/L using alkaline pH (10-11). The test values were obtained as follows: color fastness to rubbing are 3-4 for dry, 2-3 for wet, tensile strength 67.4 kg in warp direction, 43.1 in weft direction, fabric stiffness in warp direction 430.48, weft direction 344.54. The factory standard for a tensile strength of 65 kg warp direction, 40 kg weft direction, color fastness to rubbing 3 for dry rubbing and 2 for wet rubbing.
Keywords: bleach washing, denim, sodium hypochlorite, oxycellulose, color fastnes
ECONOMIC IMPACTS OF THE COVID-19 PANDEMIC ON THE HOTEL BUSINESS IN ZIMBABWE
Authors: Ncube Felicity N , Chikuta Oliver , Basera Vitalis , Baipai Rudorwashe , Mazhande Precious , Tapfuma Musawenkosi 
Published: October 2021

It is evident from literature that the spread of the Covid-19 pandemic has brought the world economiesto its ‘knees’. No industry has gone untouched by the effects of this pandemic. Globally there has beenan adverse impact on travel which is backbone of the hotel industry. This study focuses on exploringthe impact that the Covid-19 pandemic has had on Zimbabwean hotel sector. The objectives of thestudy focused on investigating the impact of Covid-19 pandemic on hotel occupancy and revenue andproposing strategies that can be implemented for recovery post the pandemic. The study adopted amixed method approach, semi-structured questionnaires were used to gather data from 29 (3-5 star)
hotel management across the various major tourism cities in Zimbabwe. Findings reveal that the Covid-19 pandemic has had an adverse impact on hotel occupancy and revenue. Occupancy and revenue
have dropped. Strategies have been employed by hotel to cope with the adverse impact of reducedoccupancy and revenue, these include working with minimal staff to avoid increases exposure, closingother parts of the hotel to reduce operational cost and operating on take out bases. It can be concludedthat hotels in Zimbabwe are not prepared for pandemics like Covid-19. It is therefore recommendedthat disaster management plans relating to pandemics be developed and implemented by hotels.
CIRCUITO DA INCOERÊNCIA: A SOCIEDADE BRASILEIRA SOFRE DE PERTURBAÇÕES DAS PERSONALIDADES DRAMÁTICAS
Authors: De Abreu Rodrigues Fabiano 
Published: October 2021

Negacionismo, histeria, necessidade de chamar a atenção, narcisismo estão entre os comportamentos mais comentados na contemporaneidade. Levando em conta que a sociedade brasileira é considerada a mais ansiosa do mundo, todos esses comportamentos, derivados da cultura, que resultou em ansiedade constante e intensificada, estão desencadeando perturbações que não necessariamente têm origem genética, mas que podem fazer parte da genética brasileira passando para as gerações futuras. Nossos comportamentos criam rastros que são passados de geração a geração. Este artigo visa determinar que, de fato, estamos vivendo a fase das personalidades dramáticas que desencadeiam transtornos e síndromes que estão adoecendo a sociedade, elevando ainda mais a ansiedade e gerando um comportamento antissocial generalizado.
Double-lined Spectroscopic Binaries in the APOGEE DR16 and DR17 Data
Authors: Kounkel Marina , Covey Kevin R. , Stassun Keivan G. , Price-Whelan Adrian M. , Holtzman Jon , Chojnowski Drew , Longa-Peña Penélope , Román-Zúñiga Carlos G. , Hernandez Jesus , Serna Javier , Badenes Carles , De Lee Nathan , Majewski Steven , Stringfellow Guy S. , Kratter Kaitlin M. , Moe Maxwell , Frinchaboy Peter M. , Beaton Rachael L. , Fernández-Trincado José G. , Mahadevan Suvrath , Minniti Dante , Beers Timothy C. , Schneider Donald P. , Barba Rodolfo , Brownstein Joel R. , García-Hernández Domingo Aníbal , Pan Kaike , Bizyaev Dmitry 
Published: October 2021

Abstract
APOGEE spectra offer ≲1 km s−1 precision in the measurement of stellar radial velocities. This holds even when multiple stars are captured in the same spectrum, as happens most commonly with double-lined spectroscopic binaries (SB2s), although random line-of-sight alignments of unrelated stars can also occur. We develop a code that autonomously identifies SB2s and higher order multiples in the APOGEE spectra, resulting in 7273 candidate SB2s, 813 SB3s, and 19 SB4s. We estimate the mass ratios of binaries, and for a subset of these systems with a sufficient number of measurements we perform a complete orbital fit, confirming that most systems with periods of <10 days have circularized. Overall, we find an SB2 fraction (F
SB2) ∼ 3% among main-sequence dwarfs, and that there is not a significant trend in F
SB2 with temperature of a star. We are also able to recover a higher F
SB2 in sources with lower metallicity, however there are some observational biases. We also examine light curves from TESS to determine which of these spectroscopic binaries are also eclipsing. Such systems, particularly those that are also pre- and post-main sequence, are good candidates for a follow-up analysis to determine their masses and temperatures.
The Infrared Evolution of Dust in V838 Monocerotis
Authors: Woodward C. E. , Evans A. , Banerjee D. P. K. , Liimets T. , Djupvik A. A. , Starrfield S. , Clayton G. C. , Eyres S. P. S. , Gehrz R. D. , Wagner R. M. 
Published: October 2021

Abstract
Luminous Red Variables are most likely eruptions that are the outcome of stellar mergers. V838 Mon is one of the best-studied members of this class, representing an archetype for stellar mergers resulting from B-type stars. As result of the merger event, “nova-like” eruptions occur driving mass loss from the system. As the gas cools considerable circumstellar dust is formed. V838 Mon erupted in 2002 and is undergoing very dynamic changes in its dust composition, geometry, and infrared luminosity providing a real-time laboratory to validate mineralogical condensation sequences in stellar mergers and evolutionary scenarios. We discuss recent NASA Stratospheric Observatory for Infrared Astronomy 5–38 μm observations combined with archival NASA Spitzer spectra that document the temporal evolution of the freshly formed (within the last ≲20 yr) circumstellar material in the environs of V838 Mon. Changes in the 10 μm spectral region are strong evidence that we are witnessing a classical dust condensation sequence expected to occur in oxygen-rich environments where alumina formation is followed by that of silicates at the temperature cools.