bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modified thread technique, 2 threads 7 days in cases of wrist ganglions: a case series
Authors: Dadhaniya Ravikumar R. , Ghoti Santosh , Dudhanale Akshay , Singh Amrendra 
Published: December 2024

Ganglion cysts are soft tissue swellings occurring most commonly in the hand or wrist, they are usually asymptomatic. The 70% cases of ganglion are observed on the dorsal side of wrist. Ganglion cysts arise from mesenchymal cells at the synovial capsular junction as a result of the continuous micro-injury. Ganglion cysts have a recurrence rate of approximately 15% to 20%. Gang et al introduced the technique of treating ganglion by passing a silk thread to induce chronic inflammation leading to obliteration of the cyst. Three cases with wrist swelling without tenderness. On examination swelling is firm consistency, slightly mobile, not adherent to underlying or overlying structures, without local rise of temperature. Ultrasonography has confirmed the diagnosis of ganglion cyst. Modified thread technique has been planned. Patient has been followed on day 3, 5, 21, 90th day. Patient has no suture site complications, with no recurrence on 3 month follow up. The cyst was stabilised and a sterile silk/linen thread on a cutting needle was passed through the cyst and taken out from the opposite side from 3 O’clock to 9 O’clock position. Second thread was passed perpendicular to first one from 12 O’clock to 6 O’clock position. The contents of ganglion were expressed out by firm pressure. Thread was removed on the seventh day irrespective of presence or absence of yellowish discharge. Patients were followed up on the fifth day after thread removal. Patients were then followed at monthly intervals for first three months. Non-surgical techniques used are aspiration, sclerotherapy, steroid injection, hyaluronidase injection, immobilization and thread technique. These have high recurrence rates. Surgical excision has lower recurrence rates, but they have a high complication rate. The thread technique is being considered as a newer option since it has recurrence rates comparable to surgical excision and complication rates comparable to nonsurgical techniques.
Effects of clothes on hyperpigmentation and sunburn on people of India
Authors: Kundu Ananya , Kundu Aditya 
Published: December 2024

Background: Many people suffer from sunburn and hyperpigmentation. Solar radiation can lead to hyperpigmentation as it easily triggers the production of melanin. Hyperpigmentation, sunburn and skin aging is determined by genetic aspects, lifestyle, and environmental factors. So, clothes likely to influence solar radiation related sufferings. The objective of the study is to test if suffering from solar radiation is associated with the nature of clothes used by the persons, what extent clothes can provide protection against solar radiation, and which type of clothes can provide maximum protection.
Methods: The Cohort study methods used for this study. The study done in two stages, first stage pilot study conducted to validate the instruments and methods used in the study. Second stage is the data collection and analysis for statistical testing and hypothesis testing.
Results: Persons wearing dark coloured loose and thick clothes covering most of their body parts can get 15 times more protection compared to the persons wearing light coloured tight and thin clothes covering less body parts.
Conclusions: People can protect themselves from solar radiation in an affordable manner by choosing appropriate clothing.
Cellular pattern of bronchoalveolar lavage fluid in suspected cases of interstitial lung diseases
Authors: Rimal Binu , Shah Niharika , Paudyal Punam , Dahal Mona , Mishra Deebya Raj 
Published: December 2024

: Bronchoalveolar lavage, a safe and less invasive treatment, is used as an auxiliary diagnostic tool when lung biopsy and radiologic imaging are insufficient in providing information to diagnosis interstitial lung disease (ILD). The aim is to analyse differential count in Bronchoalveolar lavage (BAL) fluid in suspected cases of interstitial lung diseases and hence guiding clinicians for better management of the patient.A cross-sectional study was performed for one year. Bronchoalveolar lavage fluid was recovered from thirty suspected cases of ILD, and sent to the cytopathology department where at least 400 cells were microscopically analyzed on centrifuged slides.Among 30 suspected casesNeutrophilic cellular pattern was predominantly observed in six cases ofUsual Interstitial Pneumonia, five cases of Non-specific Interstitial Pneumonia and four cases of Cryptogenic organizing pneumonia. Similarly, lymphocytic cellular pattern was predominant in four cases of Sarcoidosis. Among four cases each of Hypersensitivity Pneumonitis and Granulomatous Polyangitis, different cellular pattern was discerned in each case. Acute interstitial pneumonia and silicosis each had one case exhibiting mixed cellular pattern and increased macrophages respectively. Because subcategorization was not possible, 1 case was assigned an ILD-post-COVID status that showed Normal cellullar pattern.When treating suspected cases of ILDs, BAL fluid analysis may be essential in helping the physician confirm a diagnosis or narrow the differential diagnosis. In addition, BAL helps to predict whether a disease is acute or chronic and provide details on the condition of superadded infections to help with proper treatment.
Review of Research Methods in the Study of L2 Writing Processes
Authors: Mamadiyeva Gulbakhor , Nurmukhamedov Ulugbek 
Published: December 2024

While there are a number of books that address how to research first language (L1) and second language (L2) writing, there are not many accessible research manuals that guide novice researchers on how to research cognitive processes associated with L1/L2 writing. Researching L1/L2 writing processes and development requires a consideration of a number of variables because writing typically occurs in many different contexts (e.g., in-class, at home), settings (e.g., ESL vs. EFL), modalities (e.g., paper and pen, digital), and conditions (e.g., individual, collaborative). We find the edited volume Research Methods in the Study of L2 Writing Processes by Rosa Manchón and Julio Rocaa (2023) to be insightful for two reasons. First, all the chapters in the volume provide step-by-step directions in researching L1/L2 writing processes, highlight methodological concerns, and offer ideas on addressing those concerns. Second, the volume provides an excellent overview of key considerations in employing diverse research instruments to study writing processes.
Design e meliponicultura: experiências acadêmicas em sustentabilidade na Universidade Federal de Juiz de Fora
Authors: Mol Andre , Silva Juan de Lima Costa e , Paula Iago Augusto Campos , Sampaio Eduardo Schmitt , Veiga Gabriel Pereira 
Published: December 2024

This paper reports on academic practices related to meliponiculture conducted in the Bachelor of Design program at the Federal University of Juiz de Fora in 2023, focusing on the integration of design and sustainability. The methodology includes a structured account in three stages: (i) the development of beehives in the Product Practice I and II courses for the UFJF Botanical Garden’s meliponary; (ii) the creation of the visual identity and signage for the "Honey Trail," an environmental education project; and (iii) the organization of a sustainability fair in the Graphic Practice I course, in which meliponiculture was among the topics addressed. The report is supplemented by interviews with involved faculty and students. Results highlight the positive impact on the visibility of meliponiculture and an enhanced perception of the benefits of design interaction within the academic community.
STUDY OF THE MECHANISM OF EDGE ROUNDING OF HARD-ALLOY MODULAR AND NON-MODULAR WORM CUTTERS DURING GEAR MACHINING
Authors: Hasanov Magomedemin Isamagomedovich , Ohrimenko Oleksandr , Klochko Oleksandr , Permyakov Egor , Hubskyi Serhii , Starchenko Vitaly , Tymoshenko Bohdan 
Published: December 2024

The scientific foundations of research into the processes of rounding the edges of carbide tools during gear cutting are based on the key principles of wear theory, cutting mechanics and tribology. The formation of predicted roundings with a radius of 20–200 μm depends on cutting modes and processing conditions. The reduction of microchips on the edges and the optimization of the geometry of the cutting elements make it possible to increase the strength and wear resistance of the tools. In the initial stage of vibroabrasive processing, macrobrittle destruction of the edges with nonlinear kinetics prevails - the separation of rubble grains comparable to the rounding radius, in the final stage - microbrittle with linear - the separation of single grains comparable to the height of the irregularities. The moment of transition is determined by the amount of rounding, which is critical for macrostrength. The advantage of the exponential model obtained by solving the differential equation for describing the dependence of the rounding radius on the initial radius, the sharpening angle and the duration of processing is shown for various combinations of fillers and machined hard alloys. The kinetics of other microgeometric parameters is described by the same model, but with a finite damping instead of a linear cross section.
THEORETICAL ANALYSIS OF THE REGULATIONS OF FORMATION OF THE ROUGHNESS OF THE TREATED SURFACE DURING GRINDING AND ABRASIVE POLISHING
Authors: Novikov Fedir Vasilivyth 
Published: December 2024

Mathematical models for determining the roughness parameters of the treated surface during grinding with diamond wheels with cutting grains located at the same height and represented, respectively, in the form of cones (pointed grains), truncated cones (related to the wear of diamond grains) and spheres have been developed. It was established by calculations that in the first case the ratio of surface roughness parameters =4. In the second case, as the wear of diamond grains increases, the surface roughness parameter decreases, and the ratio can significantly exceed the value of =4. This corresponds to experimental data, according to which the ratio during grinding can vary within 4 ... 11, and during abrasive polishing it can reach a value of 30 or more, which is associated with a significant number of grains that participate in the formation of surface roughness. Even larger values of and, accordingly, smaller values of the parameter were achieved in the third case. From a physical point of view, this is related to a decrease in the known ratio (thickness of the cut to the radius of the grain) as a result of the transition from the cutting process to the process of elastic-plastic deformation of the processed material, since . Therefore, it is possible to significantly reduce the height parameters of the surface roughness during grinding and abrasive polishing by increasing the number of grains (in the form of a sphere), which participate in the formation of surface roughness, and their equal height location on the working surface of the abrasive tool.
Progressive Subchondral Bone Cyst Formation Following Autologous Chondrocyte Implantation with All-Suture Anchors: A Case Report with Histological Evaluation
Authors: Kaibara Takuma , Kondo Eiji , Matsuoka Masatake , Iwasaki Koji , Onodera Tomohiro , Momma Daisuke , Tanei Zen-ichi , Tanaka Shinya , Iwasaki Norimasa 
Published: December 2024

Abstract

Background
Subchondral bone cysts (SBCs) can significantly impact the outcomes of cartilage repair procedures such as autologous chondrocyte implantation (ACI). However, the etiology and progression of SBCs following ACI remain poorly understood. This case report highlights a progressively enlarging SBC following ACI using all-suture anchors, treated with autologous osteochondral transplantation (AOT).
Case Presentation
A 58-year-old female with progressive right knee pain, varus alignment, and Kellgren-Lawrence grade 3 osteoarthritis underwent atelocollagen-associated ACI combined with medial opening wedge high tibial osteotomy. Longitudinal radiological assessment revealed bone hole enlargement corresponding to all-suture anchor sites, with one hole continuing to expand up to 15 months postoperatively, reaching a size of 11 × 13 × 13 mm. This expanding SBC exhibited a connection to the joint cavity via a tiny fissure, scant osteosclerotic rim on CT, and fluid intensity on MRI. Histological analysis of tissue obtained during subsequent AOT revealed several findings. The SBC was located at the anterior portion of the medial femoral condyle, just beneath the all-suture anchor. Osteochondral necrosis was observed surrounding the anchor site, with no evidence of foreign body reaction. The cyst was filled with a mucoid substance and featured an aggregation of foamy macrophages. A sclerotic wall indicative of a strain response was observed. Notably, the presence of osteoclasts along the adjacent bone surface indicated ongoing bone resorption. The patient underwent AOT, which resulted in confirmed bone union. Postoperative follow-up demonstrated successful integration of the osteochondral graft and improved knee function scores over three years.
Conclusion
This case report documents SBC formation following knee surgery with all-suture anchors and provides histological evaluation of such a cyst. The observed histological findings may contribute to our understanding of SBC pathophysiology in the context of cartilage repair procedures. This case underscores the importance of secure suturing techniques in high-stress areas and suggests the potential benefit of extended post-operative monitoring of SBC progression beyond one year. These observations may inform future strategies for the early detection of SBC formation and its progression, as well as timely intervention to prevent further joint damage in similar cases, though further research is needed to establish broader clinical implications.
Does Innovation-driven Policy Optimize Urban-Energy-Consumption Structure? Evidence from National Innovation-driven City Pilot Policies
Authors: Cong Yingnan , Hou Yufei , Ji Yuan , Cai Xiaojing 
Published: December 2024

Abstract

The restructuring of energy consumption is vital for fostering green, low-carbon economic, and societal development. Innovation-driven policies, as exemplified by incentives in pilot cities, are crucial in this restructuring. In this study, theoretical analysis is performed to elucidate the impact of innovation-driven policies on the structure of urban-energy consumption. Specifically, a multi-timepoint difference-in-differences model is employed, where national innovation-driven city pilot policies are leveraged in a quasi-natural experiment to systematically assess the impact. The study demonstrates that innovation-driven policies, as showcased by national pilot programs, substantially enhance the structure of urban-energy consumption. Moreover, the impact of this policy is significantly greater in cities with lower administrative tiers, greater geographical challenges, and greater focus on environmental preservation. Tests reveal that innovation-driven policies affect the structure of urban-energy consumption via green innovation and industrial structural optimization. The findings from this study offer valuable policy guidance for optimizing innovation-driven policies to benefit the energy-consumption structure, thus fostering sustainable development within the Chinese economy.
Prediction for typical respiratory diseases development under main meteorological factors based on lag effect and neural network modeling
Authors: Liu Ting , Liu Xiao , Liu Shilei , Chen Wei , Liu Yahua 
Published: December 2024

Abstract

Respiratory diseases affect human health significantly, and understanding their impact factors and future development is conducive to helping improve effective prevention and treatment. Especially with global climate change, the impact of meteorological factors on respiratory diseases is non-negligible. This paper used 2023–2024 data of the number of respiratory disease visits and incidence in Haidian District of Beijing, combined with meteorological data for the same period, to conduct correlation analysis using Origin 2021, to develop a BP neural network time series prediction model using MATLAB R2022a. The results showed that the meteorological factors had a significant effect on the occurrence of respiratory diseases. Temperature had the greatest effect on the number of respiratory disease visits, the number of A and B flu-positive individuals and the number of COVID-19 positive individuals, with the high-risk temperature ranges of: -4 ~ 16°C and > 23°C, -3 ~ 16°C, 2 ~ 16°C, and the peaks of the risks of 6°C, 5°C, and 8°C, respectively. The lag effect of temperature on the number of visits and COVID-19 positives was not significant, but had a significant effect on the number of A and B positives, with high temperatures being the most significant. The lag effect of low air pressure had a significant effect on the number of A&B positives and persisted for 7 days, since low air pressure affects the supply of oxygen in the body and increases the susceptibility to respiratory illnesses. Lower air humidity had a significant lag effect on the number of visits and COVID-19 positives, but not on the number of A and B flu-positives. The daily average relative humidity ranges with the lowest risk for the number of visits, A and B flu positives and COVID-19 positives were 40–80%, 40–72% and 36–79%, respectively. The modeling determination coefficients of the BP neural network-based time-series prediction for the total number of visits, A and B flu-positive, and COVID-19 positive were 0.94, 0.98, and 0.92, respectively, and the validation determination coefficients were 0.88, 0.69, and 0.59, respectively, with the modeling root mean square error RMSEs of 15.34, 3.34, and 2.07, respectively, and the validation root mean square error RMSEs of 13.37, 6.21 and 2.88, respectively. The proposed model achieves accurate estimation of future visits and positive rate, especially effective in predicting the total visits. This study can provide technical support for the scientific prevention and control of respiratory diseases and scientific evidence for the development of measures related to meteorological-based medical forecasting.
Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodies
Authors: Chandra Sreeganga , Vidyadhara D J , Bäckström David , Chakraborty Risha , Ruan Jiapeng , Park Jae-Min , Mistry Pramod 
Published: December 2024

Abstract

GBA is the major risk gene for Parkinson’s disease (PD) and Dementia with Lewy Bodies (DLB), two common α-synucleinopathies with cognitive deficits. We investigated the role of mutant GBA in cognitive decline by utilizing Gba (L444P) mutant, SNCA transgenic (tg), and Gba-SNCA double mutant mice. Notably, Gba mutant mice showed early cognitive deficits but lacked PD-like motor deficits or α-synuclein pathology. Conversely, SNCA tg mice displayed age-related motor deficits, without cognitive abnormalities. Gba-SNCA mice exhibited both cognitive decline and exacerbated motor deficits, accompanied by greater cortical phospho-α-synuclein pathology, especially in layer 5 neurons. Single-nucleus RNA sequencing of the cortex uncovered synaptic vesicle (SV) endocytosis defects in excitatory neurons of Gba mutant and Gba-SNCA mice, via robust downregulation of genes regulating SV cycle and synapse assembly. Immunohistochemistry and electron microscopy validated these findings. Our results indicate that Gba mutations, while exacerbating pre-existing α-synuclein aggregation and PD-like motor deficits, contribute to cognitive deficits through α-synuclein-independent mechanisms, involving dysfunction in SV endocytosis.
Deformation properties of rock strata based on angular displacement and its hydrogeological significance
Authors: Lu Cunjin , Zhao Hui , Xu Jinpeng , Bian Kai 
Published: December 2024

Abstract

The deformation behavior of the roof and floor strata during coal seam mining plays a critical role in the development of mining-induced fractures and is an intrinsic factor in the prevention and control of coal and rock dynamic disasters, such as mine water hazards. This study investigates the critical values of the rock failure angle displacement based on the deformation performance of the strata through both laboratory and field experiments. A method for assessing the strata failure condition using the differences in deformation performance is proposed. The results indicate that the critical value of the rock failure angle displacement is closely related to the lithology, thickness, and cross-sectional area of the strata. Strata with higher strength can withstand greater loads, exhibiting larger critical angle displacements, whereas strata with lower strength experience greater angle displacements under the same load, resulting in more significant deformations. Strata with larger thicknesses and cross-sectional areas tend to have smaller critical angle displacements, indicating a reduced capacity for deformation. The angle displacement (θi) and the critical angle displacement (θ0) under unit stress differ, leading to temporal and dynamic differences in the horizontal and vertical fracture formation during strata deformation and failure. This results in the manifestation of “anisotropic seepage” behavior in groundwater, which gives rise to various forms of water hazards, including sequential water inflow, delayed water outbursts, and backflow. By using the critical values of angle displacement under unit stress as a criterion for determining strata deformation and failure, the extent of fracture development and the range of mining-induced damage zones can be more conveniently assessed compared to traditional mechanical criteria. The findings of this study are of significant practical importance for the prevention and control of mine water hazards and the protection of groundwater environments.
Common Soil Bacteria Negatively Impacts the Growth of Physarum Polycephalum
Authors: gao aidan 
Published: December 2024

Abstract

Physarum polycephalum, known as slime mold, is a multinucleate protist that develops networks to search for food. To understand the effects of bacteria and competition on P. polycephalum growth, this experiment investigated the effects of introducing Bacillus cereus, Micrococcus luteus, and Clostridium sporgenes into P. polycephalum in LB and pure agar media and measured the growth of P. polycephalum squares after four days. The introduction of bacteria to LB agar resulted in a decrease in growth of 86%, from an average of 14.6 to 1.67 squares covered with a P value < 0.001, whereas pure plates yielded no deviation from the control. These results suggest that the introduction of bacteria interferes with P. polycephalum growth, likely because bacterial clustering reduces predation ability.
Optical vortex atomic magnetometer
Authors: Deachapunya Sarayut , Buathong Sitti , Srisuphap Sorakrai , Deechuen Pissunee 
Published: December 2024

Abstract

We introduce an atomic magnetometer based on 85Rb atomic sensing in double-pass configuration, which is normally used in Dopplerfree saturation spectroscopy. Both the Zeeman and the Faraday effect take place in our technique. We enhance our magnetometer with an optical vortex (OV) beam contained orbital angular momentum (OAM) state. An advantage of our scheme is the use of a single laser source or a single wavelength. This laser beam can work as both the pump and the probe beam simultaneously. Several parameters such as laser detuning,
power, polarization, OAM state, and Rb temperature have been tested in order to optimize the setup. An accuracy of 100 pT in a large scale measurement of a few millitesla can be achieved with our recent setup. Our atomic magnetometer is simple and it has potential applications in quantum technology and even in geological surveys.