bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent Advances of Artificial Intelligence in Manufacturing Industrial Sectors: A Review
Authors: Kim Sung Wook , Kong Jun Ho , Lee Sang Won , Lee Seungchul 
Published: November 2021

AbstractThe recent advances in artificial intelligence have already begun to penetrate our daily lives. Even though the development is still in its infancy, it has been shown that it can outperform human beings even in terms of intelligence (e.g., AlphaGo by DeepMind), implying a massive potential for its broader application in various industrial sectors. In particular, the growing public interest in industry 4.0, which focuses on revolutionizing the traditional manufacturing scene, has stimulated a deeper investigation of its possible applications in the related industries. Since it has several limitations that hinder its direct usage, research on the convergence of artificial intelligence with other engineering fields, including precision engineering and manufacturing, is ongoing. This overview looks to summarize some of the important achievements made using artificial intelligence in some of the most influential and lucrative manufacturing industries in hopes of transforming the manufacturing sites.
Queerfeindliche Narrative
Authors: Sehmer Julian 
Published: November 2021

ZusammenfassungDer Beitrag skizziert aktuelle politische Entwicklungen im Kontext von Rechten für LGBTI*Q-Personen sowie daran anknüpfende Diskussionen und verortet diese innerhalb gesellschaftlicher Kultur- und Deutungskämpfe um Gender und Familie. Dabei wird deutlich, wie die Leben von queeren Menschen zunehmend zum Angriffspunkt konservativer und rechter Identitätspolitik werden. Anhand einer umfassenden Analyse einer katholischen Predigt des Vorsitzenden der Jugendkommission der Deutschen Bischofskonferenz wird exemplarisch nachgezeichnet, wie sich tradierte queerfeindliche Ablehnungs- und Abwertungsmuster in scheinbar liberale Narrative einfügen und in Verbindung mit (rechts)populistischen Argumentationsmustern Eingang in hegemoniale Diskurse finden können. Daraus werden Herausforderungen und Prämissen für sozialpädagogische Arbeit (nicht nur) für und mit queeren Jugendlichen skizziert.
Does circulating progesterone mediate the associations of single nucleotide polymorphisms in progesterone receptor (PGR)-related genes with mammographic breast density in premenopausal women?
Authors: Akinjiyan Favour A. , Han Yunan , Luo Jingqin , Toriola Adetunji T. 
Published: November 2021

AbstractProgesterone is a proliferative hormone in the breast but the associations of genetic variations in progesterone-regulated pathways with mammographic breast density (MD) in premenopausal women and whether these associations are mediated through circulating progesterone are not clearly defined. We, therefore, investigated these associations in 364 premenopausal women with a median age of 44 years. We sequenced 179 progesterone receptor (PGR)-related single nucleotide polymorphisms (SNPs). We measured volumetric percent density (VPD) and non-dense volume (NDV) using Volpara. Linear regression models were fit on circulating progesterone or VPD/NDV separately. We performed mediation analysis to evaluate whether the effect of a SNP on VPD/NDV is mediated through circulating progesterone. All analyses were adjusted for confounders, phase of menstrual cycle and the Benjamini–Hochberg false discovery (FDR) adjusted p-value was applied to correct for multiple testing. In multivariable analyses, only PGR rs657516 had a direct effect on VPD (averaged direct effect estimate = − 0.20, 95%CI = − 0.38 ~ − 0.04, p-value = 0.02) but this was not statistically significant after FDR correction and the effect was not mediated by circulating progesterone (mediation effect averaged across the two genotypes = 0.01, 95%CI = − 0.02 ~ 0.03, p-value = 0.70). Five SNPs (PGR rs11571241, rs11571239, rs1824128, rs11571150, PGRMC1 rs41294894) were associated with circulating progesterone but these were not statistically significant after FDR correction. SNPs in PGR-related genes were not associated with VPD, NDV and circulating progesterone did not mediate the associations, suggesting that the effects, if any, of these SNPs on MD are independent of circulating progesterone.
Contrast-Enhanced Mammography: Technique, Indications, and Review of Current Literature
Authors: Hannsun Gemmy , Saponaro Stephen , Sylvan Paul , Elmi Azadeh 
Published: November 2021

Abstract
Purpose of Review
To provide an update on contrast-enhanced mammography (CEM) regarding current technique and interpretation, the performance of this modality versus conventional breast imaging modalities (mammography, ultrasound, and MRI), existing clinical applications, potential challenges, and pitfalls.

Recent Findings
Multiple studies have shown that the low-energy, non-contrast-enhanced images obtained when performing CEM are non-inferior to full-field digital mammography with the added benefit of recombined post-contrast images, which have been shown to provide comparable information compared to MRI without sacrificing sensitivity and negative predictive values. While CEMs' usefulness for further diagnostic characterization of indeterminate breast findings is apparent, additional studies have provided strong evidence of potential roles in screening intermediate to high-risk populations, evaluation of disease extent, and monitoring response to therapy, particularly in patients in whom MRI is either unavailable or contraindicated. Others have shown that some patients prefer CEM over MRI given the ease of performance and patient comfort. Additionally, some health systems may find significantly reduced costs compared to MRI. Currently, CEM is hindered by the limited availability of CEM-guided tissue sampling and issues of intravenous contrast administration. However, commercially available CEM-guided biopsy systems are on the horizon, and small changes in practice workflow can be quickly adopted. As of now, MRI remains a mainstay of high-risk screening, evaluation of the extent of disease, and monitoring response to therapy, but smaller studies have suggested that CEM may be equivalent to MRI for these indications, and larger confirmatory studies are needed.

Summary
CEM is an emerging problem-solving breast imaging modality that provides complementary information to conventional imaging modalities and may potentially be used in place of MRI for specific indications and/or patient populations.
Sturm. Nie war mehr Hermeneutik in der Korpuslinguistik (gefragt)
Authors: Wilk Nicole M. 
Published: November 2021

ZusammenfassungDer Beitrag plädiert für eine höhere Sichtbarkeit und gezieltere Modellierung der qualitativ-hermeneutischen (Vor‑)Entscheidungen, die in die Anwendung korpuslinguistischer Standardverfahren eingelassen sind. Anhand verschiedener Fallbeispiele wird die datengeleitete, nicht intentionalistische Zusammenstellung von Belegsammlungen als Vorzug quantitativer Verfahren erkannt. Die Verbindung von Kollokationsnetzen mit Deutungsmustern, von Wortverbindungen mit Verstehenshorizonten, an deren Schnittstellen zentrale sprachliche Einheiten als Knotenpunkte liegen, wird mithilfe verschiedener korpus- und soziolinguistischer Ansätze modelliert. In der Frage, wie korpushermeneutisch das Herausbilden verschiedener Lesarten im Diskurs (Diskurssalienzen) begründet und erfasst werden kann, liegt das Hauptaugenmerk auf dem Prozess der Ko-Konstruktion zwischen Algorithmus und menschlicher Interpretationsinstanz als eine Art Anti-Hermeneutik ohne vorgängigen Code oder Symbolismus.
Angeborene Stoffwechselerkrankungen – Orphan Diseases aus der Sicht der Pädiatrie
Authors: Konstantopoulou Vassiliki 
Published: November 2021

ZusammenfassungOrphan Diseases, die „Waisenkrankheiten“, sind seltene oder ultraseltene Erkrankungen (SE), die gemäß einer EU-weiten Definition mit einer Prävalenz von unter 5 Individuen in 10.000 Einwohnern auftreten. Somit gibt es in Österreich geschätzt ca. 400.000 Personen, die an einer SE leiden. Geschätzt gibt es 6000–8000 Krankheiten, von denen ca. 80 % einen genetischen Ursprung (mono- oder polygenetische Ursache) haben. Ca. 50–75 % davon manifestieren sich schon im Kindesalter.Die angeborenen Stoffwechselerkrankungen („inborn errors of metabolism“ – IEM) gehören zu der Gruppe der seltenen Krankheiten (SE) oder „rare diseases“. IEM treten mit einer geschätzten Häufigkeit von 1:500–1000 Individuen auf. Ca. 80 % der IEM treten bereits im Kindesalter auf, sofern eine frühsymptomatische Form vorliegt. Aufgrund von milden Manifestationsformen wird der Rest erst im Adoleszenten- oder auch später im Erwachsenenalter entdeckt. Es ist auch möglich, dass asymptomatische Formen nie erkannt werden.Je früher eine Krankheit diagnostiziert wird, am besten bevor sie symptomatisch wird, desto früher kann eine vorhandene, oft nur symptomatische, Therapie eingesetzt werden. Existiert eine effiziente Therapie, sind die Chancen für eine verbesserte Lebensqualität, sowohl für die Patienten als auch für die betroffenen Familien, groß.Die Entdeckung einer seltenen Erkrankung bedeutet jedoch eine diagnostische Herausforderung, weshalb die betroffenen Patienten oft eine lange Diagnoseodyssee erleben.Nachdem ca. 80 % der IEM im Kindesalter auftreten, sich aber auch später in der Adoleszenz manifestieren können, sind auch die Pädiater gefordert, ihr medizinisches Wissen auf diesem Feld zu erweitern.
Mobile robot with failure inspection system for ferromagnetic structures using magnetic memory method
Authors: Montes de Oca-Mora N. J. , Woo-Garcia R. M. , Juarez-Aguirre R. , Herrera-May A. L. , Sanchez-Vidal A. , Ceron-Alvarez C. A. , Restrepo J. , Algredo-Badillo I. , Lopez-Huerta F. 
Published: November 2021

AbstractFlaws or cracks are one of the major failures in oil and gas pipeline networks. The early detection of these failures is very important for the safety of the industry, and this last requires of analysis for non-destructive testing (NDT), which is reliable, inexpensive and easy to implement. In this paper, we propose the development of an embedded prototype mounted on a mobile robot for the inspection of defects in ferromagnetic plates. This prototype has two embedded systems (control and data acquisition), which are based on a microcontroller of 8 and 32 bits, respectively. On the one hand, the first system for control has the logic to govern the sensors and motors that will allow to the robot moves with autonomous way during 45 min. While, the second system presents an algorithm for storing, processing and sending the data obtained from the sensors, being able to measure variations in the magnetic field in the order of 0.1 µT. Magnetic-field reading tests have been carried out on control ASTM A-27 ferromagnetic plates, obtaining experimental response in the 3 axes of the magnetic domains, which is very close to the expected results by the magnetic-flux density model that is calculated from the fields E and B derived from the equations of a Hertz dipole, and developed in the high-level Python programming language. The prototype proposed for NDT can detect geometric defects in the range of millimeters, producing changes in the density of the magnetic field in the order of thousands of µT.
222 nm ultraviolet radiation C causes more severe damage to guard cells and epidermal cells of Arabidopsis plants than does 254 nm ultraviolet radiation
Authors: Otake Momo , Okamoto Yoshiyama Kaoru , Yamaguchi Hiroko , Hidema Jun 
Published: November 2021

AbstractLamps that emit 222 nm short-wavelength ultraviolet (UV) radiation can be safely used for sterilization without harming human health. However, there are few studies on the effects of 222 nm UVC (222-UVC) radiation exposure on plants compared with the effects of germicidal lamps emitting primarily 254 nm UVC (254-UVC) radiation. We investigated the growth inhibition and cell damage caused by 222-UVC exposure to Arabidopsis plants, especially mitochondrial dynamics, which is an index of damage caused by UVB radiation. Growth inhibition resulted from 254-UVC or 222-UVC exposure depending on the dose of UVC radiation. However, with respect to the phenotype of 222-UVC-irradiated plants, the leaves curled under 1 kJ m−2 and were markedly bleached under 10 kJ m−2 compared with those of plants irradiated with 254-UVC. The cellular state, especially the mitochondrial dynamics, of epidermal and mesophyll cells of Arabidopsis leaves exposed to 254-UVC or 222-UVC radiation was investigated using Arabidopsis plants expressing mitochondrial matrix-targeted yellow fluorescent protein (MT-YFP) under the control of Pro35S to visualize the mitochondria. 222-UVC (1 or 5 kJ m−2) severely damaged the guard cells within the epidermis, and YFP signals and chloroplast autofluorescence in guard cells within the epidermis exposed to 222-UVC (1 or 5 kJ m−2) were not detected compared with those in cells exposed to 254-UVC radiation. In addition, 222-UVC irradiation led to mitochondrial fragmentation in mesophyll cells, similar to the effects of 254-UVC exposure. These results suggest that 222-UVC severely damages guard cells and epidermal cells and that such damage might have resulted in growth inhibition.
Improving antibiotic prescribing for pediatric acute respiratory tract infections: A cluster randomized trial to evaluate individual versus clinic feedback
Authors: Clegg Herbert W. , Ezzo Stephen J. , Flett Kelly B. , Anderson William E. 
Published: November 2021

Abstract

Objective:
To assess the effect of individual compared to clinic-level feedback on guideline-concordant care for 3 acute respiratory tract infections (ARTIs) among family medicine clinicians caring for pediatric patients.

Design:
Cluster randomized controlled trial with a 22-month baseline, 26-month intervention period, and 12-month postintervention period.

Setting and participants:
In total, 26 family medicine practices (39 clinics) caring for pediatric patients in Virginia, North Carolina, and South Carolina were selected based upon performance on guideline-concordance for 3 ARTIs, stratified by practice size. These were randomly allocated to a control group (17 clinics in 13 practices) or to an intervention group (22 clinics in 13 practices).

Interventions:
All clinicians received an education session and baseline then monthly clinic-level rates for guideline-concordant antibiotic prescribing for ARTIs: upper respiratory tract infection (URI), acute bacterial sinusitis (ABS), and acute otitis media (AOM). For the intervention group only, individual clinician performance was provided.

Results:
Both intervention and control groups demonstrated improvement from baseline, but the intervention group had significantly greater improvement compared with the control group: URI (odds ratio [OR], 1.62; 95% confidence interval [CI], 1.37–1.92; P < 0.01); ABS (OR, 1.45; 95% CI, 1.11–1.88; P < 0.01); and AOM (OR, 1.59; 95% CI, 1.24–2.03; P < 0.01). The intervention group also showed significantly greater reduction in broad-spectrum antibiotic prescribing percentage (BSAP%): odds ratio 0.80, 95% CI 0.74-0.87, P < 0.01. During the postintervention year, gains were maintained in the intervention group for each ARTI and for URI and AOM in the control group.

Conclusions:
Monthly individual peer feedback is superior to clinic-level only feedback in family medicine clinics for 3 pediatric ARTIs and for BSAP% reduction.

Trial registration:
ClinicalTrials.gov identifier: NCT04588376, Improving Antibiotic Prescribing for Pediatric Respiratory Infection by Family Physicians with Peer Comparison.
Analysis and Critique of the Advocacy Paper Towards Inclusive Education: A Necessary Process of Transformation
Authors: Stephenson Jennifer , Ganguly Rahul 
Published: November 2021

AbstractThe increasing inclusion of students with disabilities in regular classes still leads to debate and many advocate for full inclusion of all students. Arguments for full inclusion are generally rights-based, but proponents also claim research supports the effectiveness of full inclusion over specialist provision for all students with disabilities. In this article, we analyse and critique the use of the research literature in an Australian advocacy paper as an example of the broad claims made concerning full inclusion. We examine the extent to which the sources used provide conclusive evidence about the merits of full inclusion. We find the advocacy paper relies heavily on opinion and non-peer-reviewed literature, with little use of quantitative research that compares outcomes for students in different settings. We suggest that policymakers should treat the conclusions drawn in this paper cautiously and give due consideration to the literature that is not supportive of full inclusion.
Two-week-wait referrals in otolaryngology in a tertiary centre: cross-sectional study of benign outcomes, with a systematic review
Authors: Mettias B , Charlton A , Ashokkumar S 
Published: November 2021

AbstractObjectiveThe two-week-wait referral is designed to improve early detection in cancer patients. This retrospective study analysed those ENT two-week-wait referrals to out-patient clinics in a tertiary head and neck oncology centre, from January to June 2018, which were not compliant with National Institute for Health and Care Excellence guidelines (2015 update).MethodsReferral symptoms were statistically analysed against National Institute for Health and Care Excellence guidelines, with detailed analysis of reasons for non-compliance. In addition, a systematic review of similar previously published articles was conducted.ResultsThere were 1107 patients referred through the two-week-wait pathway. Of these referrals, 52 per cent were compliant with National Institute for Health and Care Excellence 2015 guidelines. Six errors were identified for non-compliant referrals, most commonly inconsistencies in referral (e.g. globus sensation) and intermittent disease course (e.g. intermittent hoarseness). Of all patients referred, 93 per cent were diagnosed with benign conditions, with laryngopharyngeal reflux being the commonest. Twenty-two per cent of referred patients were discharged after the first visit.ConclusionTwo-week-wait referral is inappropriately overused. There are many non-compliant referrals, and most of the outcomes are benign.
Schistosomiasis in the People's Republic of China – down but not out
Authors: Gordon Catherine A. , Williams Gail M. , Gray Darren J. , Clements Archie C. A. , Zhou Xiao-Nong , Li Yuesheng , Utzinger Jürg , Kurscheid Johanna , Forsyth Simon , Addis Alene Kefyalew , Zhou Jie , Li Zhaojun , Li Guangpin , Lin Dandan , Lou Zhihong , Li Shengming , Ge Jun , Xu Jing , Yu Xinling , Hu Fei , Xie Shuying , Chen Jie , Shi Tao , Li Chong , Zheng Huajun , McManus Donald P. 
Published: November 2021

AbstractSchistosomiasis has been subjected to extensive control efforts in the People's Republic of China (China) which aims to eliminate the disease by 2030. We describe baseline results of a longitudinal cohort study undertaken in the Dongting and Poyang lakes areas of central China designed to determine the prevalence of Schistosoma japonicum in humans, animals (goats and bovines) and Oncomelania snails utilizing molecular diagnostics procedures. Data from the Chinese National Schistosomiasis Control Programme (CNSCP) were compared with the molecular results obtained.Sixteen villages from Hunan and Jiangxi provinces were surveyed; animals were only found in Hunan. The prevalence of schistosomiasis in humans was 1.8% in Jiangxi and 8.0% in Hunan determined by real-time polymerase chain reaction (PCR), while 18.3% of animals were positive by digital droplet PCR. The CNSCP data indicated that all villages harboured S. japonicum-infected individuals, detected serologically by indirect haemagglutination assay (IHA), but very few, if any, of these were subsequently positive by Kato-Katz (KK).Based on the outcome of the IHA and KK results, the CNSCP incorporates targeted human praziquantel chemotherapy but this approach can miss some infections as evidenced by the results reported here. Sensitive molecular diagnostics can play a key role in the elimination of schistosomiasis in China and inform control measures allowing for a more systematic approach to treatment.
Provider insights on shared decision-making with families affected by CHD
Authors: Pinto Nelangi M. , Patel Angira , Delaney Rebecca K. , Donofrio Mary T. , Marino Bradley S. , Miller Stephen , Ozanne Elissa M. , Zickmund Susan L. , Karasawa Michelle H. , Pershing Mandy L. , Fagerlin Angela 
Published: November 2021

AbstractBackground and Objectives:Little data exist on provider perspectives about counselling and shared decision-making for complex CHD, ways to support and improve the process, and barriers to effective communication. The goal of this qualitative study was to determine providers’ perspectives regarding factors that are integral to shared decision-making with parents faced with complex CHD in their fetus or newborn; and barriers and facilitators to engaging in effective shared decision-making.Methods:We conducted semi-structured interviews with providers from different areas of practice who care for fetuses and/or children with CHD. Providers were recruited from four geographically diverse centres. Interviews were recorded, transcribed, and analysed for key themes using an open coding process with a grounded theory approach.Results:Interviews were conducted with 31 providers; paediatric cardiologists (n = 7) were the largest group represented, followed by nurses (n = 6) and palliative care providers (n = 5). Key barriers to communication with parents that providers identified included variability among providers themselves, factors that influenced parental comprehension or understanding, discrepant expectations, circumstantial barriers, and trust/relationship with providers. When discussing informational needs of parents, providers focused on comprehensive short- and long-term outcomes, quality of life, and breadth and depth that aligned with parental goals and needs. In discussing resources to support shared decision-making, providers emphasised the need for comprehensive, up-to-date information that was accessible to parents of varying situations and backgrounds.Conclusions:Provider perspectives on decision-making with families with CHD highlighted key communication issues, informational priorities, and components of decision support that can enhance shared decision-making.