bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early Intraocular Pressure After Phacoemulsification Combined With Trabeculectomy
Authors: Hopkins J Jill , Apel Andrew , Trope Graham E , Rootman David S 
Published: April 2021

* BACKGROUND AND OBJECTIVE: To determine the efficacy of combined phacoemulsification-trabeculectomy in preventing early postoperative increases in intraocular pressure (IOP).
* PATIENTS AND METHODS: Eighty patients were enrolled in a prospective cohort study. Thirty-six patients with cataracts and uncontrolled glaucoma underwent combined phacoemulsification-trabeculectomy, and 44 patients with cataracts underwent phacoemulsification alone. The operations were performed in a standardized manner by one surgeon. IOP was measured at 4 hours, 1 day, and 7 days after surgery. The need for intervention (digital massage, medications) and the presence of complications were documented.
* RESULTS: Four hours after surgery, 5.5% of patients undergoing the combined procedure had IOPs greater than 30 mm Hg, compared with 22.7% of phacoemulsification patients P < .05). No significant difference in IOP was found between the groups at postoperative day 1 or day 7.
* CONCLUSION: These results suggest that combined phacoemulsification-trabeculectomy protects against early postoperative elevations in IOP. This finding may influence the surgical management of cataracts in patients with poorly controlled glaucoma and significant compromise of visual field or optic nerve.
[Ophthalmic Surg Lasers 1998;29:273-279.]
Reproducibility of Retinal Thickness Measurements in Normal Eyes Using Optical Coherence Tomography
Authors: Baumann Matthias , Gentile Ronald C , Liebmann Jeffrey M , Ritch Robert 
Published: April 2021

* BACKGROUND AND OBJECTIVE: To determine the reproducibility of retinal thickness measurements in normal eyes using optical coherence tomography (OCT).
* PATIENTS AND METHODS: Multiple 3.20mm vertical cross-sectional images through the center of fixation of consecutive patients with normal results on ocular examinations were obtained. Each image was divided into seven 320-pm segments. Regional retinal thicknesses for each section were measured using both the manually assisted (requiring observer localization of reflectivity peaks) and the automated modes (observer-independent measurement) of the computer software.
* RESULTS: Eighteen right eyes were studied. The mean coefficient of variation was less than 10% for all locations using the manually assisted method (average standard deviation less than 17 pm [range 9 to 16 pm]). The automated method was less reliable, with a coefficient of variation greater than 10% for locations within 500 pm of fixation. Automated measurements at fixation were the least reproducible because of poor internal limiting membrane reflectivity.
* CONCLUSION: OCT is capable of reproducible measurement of retinal thickness in normal eyes. Computer-driven, automated measurement of retinal thickness within 500 pm of fixation needs to be refined and its reproducibility reassessed in this region.
[Ophthalmic Surg Lasers 1998;29:280-285.]
Pars Plana Vitrectomy, Lensectomy, or Extraction in Transscleral Intraocular Lens Fixation for the Management of Dislocated Lenses in a Family With Marfan's Syndrome
Authors: Omulecki Wojciech , Nawrocki Jerzy , Palenga-Pydyn Dorota , Sempinska-Szewczyk Joanna 
Published: April 2021

* BACKGROUND AND OBJECTIVES: Congenital lens subluxation may be a difficult therapeutic problem. Surgical treatment options include iris manipulation or lens discission, aspiration, intracapsular or extracapsular extraction, and lensectomy through the pars plana. It is not established which kind of aphakic correction is the most appropriate in these cases.
* PATIENTS AND METHODS: A father and his two sons with Marfans syndrome were operatively treated for lens dislocation in both eyes. Pars plana vitrectomy was done in all eyes. Dislocated lenses were removed by lensectomy in three eyes and with an intracapsular method in three eyes. The outside-in scleral fixation technique was used for primary posterior chamber intraocular lens (PC IOL) implantation in all cases.
* RESULTS: All eyes achieved good visual acuity (20/20-20/25). Time of observation ranged between 8 and 20 months. There were no intraoperative or postoperative complications.
* CONCLUSION: Pars plana vitrectomy and primary scleral-fixated IOL implantation is a safe procedure and gives good visual rehabilitation in adult patients with Marfan's syndrome.
[Ophthalmic Surg Lasers 1998;29:375-379.]
Transcanalicular Laser-Assisted Revision of Failed Dacryocystorhinostomy
Authors: Woo Kyung In , Moon Seong Neon , Kim Yoon-Duck 
Published: April 2021

* BACKGROUND AND OBJECTIVE: Despite the high success rate of external dacryocystorhinostomy (DCR), recurrent tearing after DCR can be troublesome. The authors performed transcanalicular revision in 6 patients with failed DCR.
* PATIENTS AND METHODS: With the use of a continuous wave Nd:YAG laser with a sclerostomy probe, the internal ostium was reopened by a transcanalicular approach. The authors applied 0.4 mg/ml of mitomycin-C around the opening for 5 minutes intranasally and inserted a silicone tube as a stent.
* RESULTS: A total of 7 operations were performed in 6 patients. The operation was successful after the first revision in 5 of the 6 patients, but 1 of the patients required a second procedure.
* CONCLUSIONS: The transcanalicular laserassisted revision has several advantages. It is simple and fast, skin incision is avoided, there is good hemostasis, it is less traumatic, and there is less postoperative morbidity.
[Ophthalmic Surg Lasers 1998;29:451-455.]
Three-Year Follow-up of Trabeculectomies Performed With Different Concentrations of Mitomycin-C
Authors: Mietz Holger , Krieglstein Günter K 
Published: April 2021

* BACKGROUND AND OBJECTIVE: Mitomycin-C is effective for improving success rates of trabeculectomies. The authors sought to determine long-term success rates and complications by studying two widely used concentrations.
* PATIENTS AND METHODS: Trabeculectomies were performed with mitomycin-C (MMC) in concentrations of 0.5 mg/ml (group 1) and 0.2 mg/ml (group 2) in a prospective, nonrandomized fashion. Patients were observed for at least 3 years, and all follow-up data were analyzed in addition to the preoperative and postoperative conditions and complications.
* RESULTS: A total of 51 and 40 eyes (groups 1 and 2, respectively) were observed for 3 years. The majority of the eyes had repeat trabeculectomy. Complete surgical success was reached in 76% and 63%, respectively. The mean intraocular pressure (IOP) in the two groups decreased significantly, and the decrease was larger in the MMC 0.5 mg/ml group (P < .015). The mean visual acuity did decrease in the two groups, but this was not significant. Complications included short-term and long-term hypotony, conjunctival dehiscence, choroidal detachments, and endophthalmitis. Trabeculectomies failed both within the first 3 months (n = 4; 4%) and later (n = 11; 12%).
* CONCLUSION: Three-year results of trabeculectomies performed with MMC are promising. A doseresponse effect of the concentration of MMC and IOP levels is present, suggesting that the higher concentration leads to lower IOP values. Despite the antimetabolic effect of MMC, trabeculectomies fail in both the short-term and the long-term.
[Ophthalmic Surg Lasers 1998;29:628-634.]
Outcomes of Extracapsular Cataract Extraction and Phacoemulsification Performed in a University Training Program
Authors: Albanis Chris V , Dwyer Maureen A , Ernest J Terry 
Published: April 2021

* BACKGROUND AND OBJECTIVES: As the number of older Americans increases, more patients will need cataract extraction surgery. Outcome studies will be necessary to assess and improve the quality of care. This study documents the outcomes of extracapsular cataract extraction (ECCE) performed at Oak Forest County Hospital (OFH) and phacoemulsification (PE) performed at the University of Chicago Hospitals (UCH) by residents who were training at the University of Chicago.
* PATIENTS AND METHODS: Residents train using ECCE during their second year at OFH, and learn PE at the UCH during their third year. The authors performed a chart review of all patients who had undergone ECCE at OFH (N = 52) and all patients who had undergone PE at the UCH (N = 343) from 1995 through 1997. Complete preoperative, intraoperative, and postoperative clinical data were recorded on the American Society of Cataract and Refractive Surgery database.
* RESULTS: There were no intraoperative complications at OFH, and 23 of 52 (44%) of the eyes had a final best-corrected visual acuity (BCVA) of 20/40 or better. At the UCH, vitreous loss occurred in 16 of 343 (5%) of the PE patients. A final BCVA of 20/40 or better was achieved in 300 of 343 (87%) of the PE eyes.
* CONCLUSIONS: The visual outcomes of patients who undergo ECCE at a county hospital are poor, but the surgical complications are minimal. The visual outcomes of patients who undergo PE at a university hospital are good, but the complication rates are slightly higher.
[Ophthalmic Surg Lasers 1998;29:643-648.]
Corneal Refractive and Endothelial Changes Following THC:YAG (Holmium) Laser Sclerostomy
Authors: Trible John R , Olander Kenneth W , Koenig Steven B 
Published: April 2021

* BACKGROUND AND OBJECTIVE: To determine the effect of THC:YAG (holmium) laser sclerostomy on corneal curvature and endothelial cell counts.
* PATIENTS AND METHODS: One hundred twenty-five cases were reviewed for high postoperative corneal astigmatism (> 5 D) or preoperative and postoperative endothelial cell count measurements in eyes without preoperative evidence of corneal endothelial compromise.
* RESULTS: Nine patients had keratometry readings at 2 to 3 months with documented corneal astigmatic changes of 5-62 to 12 D (mean 7.27 ±2.16 D). Sixteen eyes of 14 patients studied with specular microscopy had central mean endothelial cell count reductions of 6.5% following THC:YAG laser sclerostomy. The total energy applied correlated with the percentage reduction in endothelial cell counts (r = .507, P = .045, n = 16, Spearman correlation).
* CONCLUSION: Higher laser energy levels can result in high corneal astigmatism, which in some cases may be persistent, and a reduction in endothelial cell count.
[Ophthalmic Surg Lasers 1998;29:733-737.]
Long-Term Results of Various Anterior Capsulotomies and Radial Tears on Intraocular Lens Centration
Authors: Oner F Hakan , Durak Ismet , Soylev Meltem , Ergin Mehmet 
Published: April 2021

* BACKGROUND AND OBJECTIVE: To evaluate the long-term effects of various anterior capsulotomies and radial tears on intraocular lens (IOL) centration.
* MATERIALS AND METHODS: Ninety-five eyes of 87 senile cataract patients operated with extracapsular technique were evaluated in IOL tilt and decentration with a new method of measurement. According to the type of anterior capsulotomy and number of radial tears, five groups were constituted as, can opener, envelope, continous curvilinear capsulorrhexis (CCC), CCC with one radial tear (relaxing incision at quadrant 12), and CCC with two relaxing incisions (relaxing incisions at quadrants 6 and 12), respectively.
* RESULTS: Early decentration and tilt in groups CCC and CCC with one radial tear were significantly lower than the other groups (P < 0.05). Late decentration and tilt in the CCC group were significandy lower than the other groups (P < 0.01). Highest values of tilt and decentration were determined in envelope capsulotomy. Additional symmetric relaxing incision at quadrant 6 revealed no effect on the prevention of decentration and tilt compared to one relaxing incision.
* CONCLUSION: CCC with one radial tear is not ideal but sufficient for IOL centration. All other anterior capsulotomy techniques, other than intact CCC, do not guarantee the IOL centration.
[Ophthalmic Surg Lasers 2001;32:118-123]
Chorioretinitis Sclopetaria from BB Ex Memoria
Authors: Otto Clifton S , Nixon Karen L , Mazzoli Robert A , Raymond William R , Ainbinder Darryl J , Hansen Elizabeth A , Krolicki Thaddeus J 
Published: April 2021

Abstract. Chorioretinitis sclopetaria presents a characteristic pattern of choroidal and retinal changes caused by a high velocity projectile passing into the orbit, in close proximity to the globe. While it is unlikely that a patient should completely forget the trauma causing such damage, preserved or compensated visual function may blur the patient's memory of these events over time. Characteristic physical findings help to clarify the antecedent history. Despite the lack of an acknowledged history of ocular trauma or surgery, in our case, the characteristic ocular findings discovered at presentation allowed for recognition of the underlying etiology. Because of good visual function, the patient had completely forgotten about the trauma that occurred 12 years earlier. Strabismus surgery was performed for treatment of the presenting symptomatic diplopia. The pathognomonic findings in chorioretinitis sclopetaria are invaluable in correctly diagnosing this condition, especially when a history of ocular trauma is unavailable.
[Ophthalmic Surg Lasers 2001;32:152-155]
Persistent Indocyanine Green Angiographic Findings in Multiple Evanescent White Dot Syndrome
Authors: Yen Michael T , Rosenfeld Philip J 
Published: April 2021

Abstract. This report describes unique findings of persistent peripapillary and posterior pole hypofluorescence on indocyanine green angiography (ICGA) in multiple evanescent white dot syndrome (MEWDS). A 38-year-old woman experienced a sudden decrease of visual acuity in the left eye. Multiple white lesions were seen on fundus examination. Fluorescein angiography, indocyanine green angiography, and automated perimetry were performed. Fundus appearance and fluorescein angiography were consistent with the diagnosis of MEWDS. Automated perimetry revealed an enlarged blind spot. ICGA revealed a zone of hypofluorescence surrounding the optic disc and throughout the posterior pole. The enlarged blind spot resolved after seven weeks along with the signs and symptoms of MEWDS. Nine months after initial presentation, ICGA revealed persistent peripapillary and posterior pole hypofluorescence. Resolution of the enlarged blind spot and return of vision does not completely correlate with the disappearance of hypofluorescent areas on ICGA. These findings suggest that MEWDS may result in persistent abnormalities in choroidal circulation even after clinical symptoms resolve.
[Ophthalmic Surg Lasers 2001;32:156-158]
Adjuvant Methods in Macular Hole Surgery: Intraoperative Plasma-Thrombin Mixture and Postoperative Fluid-Gas Exchange
Authors: Blumenkranz Mark S , Ohana Esther , Shaikh Saad , Chang Stanley , Coll Gustavo , Morse Lawrence S , De Bustros Serge 
Published: April 2021

* BACKGROUND AND OBJECTIVE: The opti mal method for surgical management of idiopathic macular holes remains unknown. Adjuvant methods including intraoperative cytokines and postoperative fluid-gas exchange with and without laser have been described. We report on the safety and final results of routine intraoperative autologous plasma-thrombin mixture and postoperative fluid-gas exchange when necessary as an adjunct to the surgical therapy of this disease.
* PATIENTS AND METHODS: A consecutive series of 1 14 patients (mean age 66.9 years) with primary idiopathic full thickness Stage II, III, and IV macular holes were primarily treated by vitrectomy, fluid/perfluorocarbon gas exchange, and application of autologous plasma-thrombin mixture to the macular hole. Visible epiretinal membranes were peeled but the normal appearing internal limiting membrane was not routinely stripped. Outcome measures included final Snellen visual acuity, rate of macular hole closure, complications, and number of supplemental procedures performed.
* RESULTS: Closed at one month, were 110 of 121 (91%) macular holes, including two that underwent repeat fluid/gas exchange and laser within the first two weeks after surgery. At the time of final follow-up (mean: 10.9 months), 110 of 121 (91%) macular holes were closed. This included 8 of 9 eyes that had reopening of the macular hole between one and 2 1 months successfully treated by repeat fluid-gas exchange and 2 eyes that underwent a second successful pars plana vitrectomy, membrane peeling, and repeat fluid-gas exchange. Overall, 98 of 121 eyes overall (81%) were successfully treated by a single surgery; 94 of 121 (78%) achieved two lines or greater of visual improvement; 83 of 121 (69%) achieved 20/70 or better vision; and 47 eyes (39%) achieved 20/40 or better vision. Complications in this series included infectious endophthalmitis (1 eye), intraoperative retinal break (2 eyes), late retinal detachment (5 eyes), transient mild intraocular pressure elevation (46 eyes), inflammatory response (six eyes), epiretinal membrane (6 eyes), intraretinal hemorrhages (1 eye), and cataract (33 of 99 phakic eyes underwent cataract extraction during the follow-up).
* CONCLUSION: A combination of intravitreal perfluorocarbon gas and autologous plasma-thrombin mixture (tissue glue) was well tolerated in most patients and did not result in any specific long-term complications. The use of supplemental fluid-gas exchange when necessary improved the final success rate. Further well-controlled and randomized studies will be required to determine the efficacy of this as an adjunct or alternative to other methods of treatment for macular holes.
[Ophthalmic Surg Lasers 2001;32:198-207]
Laser Therapy in the Management of Choroidal Breast Tumor Metastases
Authors: Levinger Samuel , Merin Saul , Seigal Ruth , Pe'er Jac 
Published: April 2021

* PURPOSE: To evaluate the potential of laser photocoagulation as a method of treating small metastatic lesions of breast carcinoma in the choroid.
* METHODS: The 10 eyes of 7 patients were treated by Krypton red or argon green laser applications for small choroidal breast carcinoma metastasis with serous detachment of the retina. Before treatment 5 eyes had visual acuity of finger counting and 5 eyes had visual acuity of 6/15 or better. The treatment was repeated once in all eyes, except 1 eye in which it was repeated 3 times.
RESULTS: In all eyes, one to two weeks after the treatment the tumor shrunk, the subretinal serous detachment absorbed, the retina flattened, and the visual acuity improved to 6/6-6/21. No reduction in vision was seen after the second treatment until the end of the follow-up period. In 1 eye, new tumors located elsewhere were again twice successfiilly treated. Patients reported a significant improvement of their quality of vision, as judged subjectively.
* CONCLUSIONS: Laser treatment is a feasible, easy, rapid, and effective therapy for small choroidal breast carcinoma.
[Ophthalmic Surg Lasers 2001;32:294-299]
Postoperative Complications After Simultaneous Vitrectomy and Cataract Surgery
Authors: Suzuki Yukihiko , Sakuraba Tomoki , Mizutani Hideyuki , Matsuhashi Hideaki , Nakazawa Mitsuru 
Published: April 2021

* OBJECTIVE: We reviewed postoperative complications after simultaneous vitrectomy, phacoemulsification, aspiration, and acryl lens insertion.
* PATIENTS AND METHODS: Combined surgery was performed in 316 eyes of 279 patients between 1995 and 1997. Postoperative observation was continued in all of them for more than 6 months. The diagnoses that led to vitrectomy included diabetic retinopathy in 155 eyes, rhegmatogenous retinal detachment in 64 eyes, macular hole in 43 eyes, and other diseases in 93 eyes. The rate of postoperative complications that needed any reoperation was investigated.
* RESULTS: Reoperations were needed for intravitreal hemorrhage in 23 eyes (7.3%), retinal detachment in 15 eyes (4.7%), rubeotic glaucoma in 6 eyes (1.9%), and other conditions in 4 eyes (1.3%). Among them, reoperations were performed on 13 eyes (4.1%) twice and more. A removal of an intraocular lens was needed in 16 eyes (5.1%) for treatment of vitreoretinal disease. In patients with diabetic retinopathy, reoperations were needed for intravitreal hemorrhage in 21 eyes (13.5%), rubeotic glaucoma in 6 eyes (3.9%), other diseases in 4 eyes (2.6%), and a removal of an intraocular lens was needed in 10 eyes (6.5%) at a higher rate than the other disease.
* CONCLUSION: This combined surgery is considered advantageous for removing peripheral vitreous, while preventing these complications is important for preserving visual function.
[Ophthalmic Surg Lasers 2001;32:391-396]
Surgical Removal of Submacular Choroidal Neovascularization: A Clinicopathologic Study and Factors Influencing Visual Outcomes
Authors: Corey Richard P , Scott Ingrid U , Flynn Harry W , Rosa Robert H , Murray Timothy G 
Published: April 2021

* BACKGROUND AND OBJECTIVE: Clinical and histopathologic characteristics of submacular choroidal neovascular membranes (CNV) are investigated and features predictive of postoperative complications or poorer visual outcome following CNV removal are identified.
* MATERIALS AND METHODS: Records of patients who underwent submacular CNV removal at Bascom Palmer Eye Institute between 1991 and 1998 are reviewed.
* RESULTS: At 6 months postoperatively, vision was stable or improved in 19/26 (73%) eyes, with 15/26 (58%) having 20/200 to 20/400 vision. Postoperative retinal detachment occurred more commonly in age-related macular degeneration eyes (AMD) (P <0.05), and CNV recurrence occurred most frequently in presumed ocular histoplasmosis (POHS) eyes (P <0.05). The one eye with an extrafoveal CNV in-growth site had the largest improvement in vision postoperatively. Choroid in the specimen was associated with worse postoperative vision (P = 0.05).
* CONCLUSION: Submacular CNV removal achieves visual stabilization at the 20/200 to 20/400 level in most eyes. Potential risk factors for postoperative complications or poorer visual outcome include the underlying disease process, subfoveal in-growth site of CNV, and presence of choroid in the specimen.
[Ophthalmic Surg Lasers 2001;32:406-418]
5-Fluorouracil-Needling and Paracentesis Through the Failing Filtering Bleb
Authors: Ophir Avinoam , Wasserman Daniel 
Published: April 2021

* BACKGROUND AND OBJECTIVE: Standard needle revision of the filtering bleb after glaucoma filtration surgery has many disadvantages. This study reports the technique and outcome of a modified needling of the failing bleb.
* PATIENTS AND METHODS: Consecutive patients who presented with increased intraocular pressure (IOP) and open internal ostium were included m this prospective study. When their IOP rose to levels >20 mm Hg despite various therapeutic regimens and visibility of the sclerostomy site was unclear, the modified needling technique was conducted. In each needling, a total dose of 1 mg (0.1 mL) of 5-fluorouracil (FU) was administered subconjunctivally, adjacent and into the bleb. The needle was then passed via the bleb, anterior to the sclera, through the anterior limbus to penetrate intracamerally. Standard treatment to inhibit bleb scarring followed.
* RESULTS: Twelve 5-FU-needle revisions were performed on 8 eyes. The first needle revision was performed 51.1 ±36.2 days (range, 5-117) postoperative!/. IOP decreased from 31.0±5.7 (range, 25-43) mm Hg with 0.6±0.9 (range, 0-2) hypotensive medications to 15.5±2.6 mm Hg (range, 12-19) with 0.9±1.1 medications (range, 0-3), 11.3±4.9 months (range, 8-23) after the only or second (last) needling (P=0.012). In all eyes, the filtering bleb became diffused; in 7 eyes, it remained diffusely elevated or shallow-diffused.
* CONCLUSION: Relatively few needle revisions of the filtering bleb by a modified approach that bypassed the activated scarring tissue contributed to the restoration of IOP control. It is possible that the 5-FU-needle revision may offer advantages over the standard approach. A larger sample and a controlled study are required to validate these considerations.
[Ophthalmic Surg Lasers 2002;33:109-116]