bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on the Application of Desktop Virtual Reality in Middle School Physics Experiment Teaching under the Cooperative Enquiry Mode
Authors: Ma Xiulin , Fan Yu , Wang Teng , Wang Jiayong , Tian Shumin 
Published: December 2024

As one of the important means of assisting experimental teaching, immersive virtual reality is limited by wearable devices in actual teaching environments, making it difficult to achieve large-scale application. In contrast, desktop virtual reality provides a feasible way to solve this problem with its low cost and convenience. However, there is currently a lack of in-depth research on how to effectively use desktop virtual reality to organize teaching activities. In view of this, this study carried out collaborative inquiry-based physics experimental teaching activities with the support of traditional real situations and desktop virtual reality . Through a comprehensive evaluation of the physics experimental abilities and related factors of students in the experimental group, the study found that: under the cooperative inquiry mode, physics experiment teaching organized based on desktop virtual reality technology can not only improve student performance, but also significantly alleviate some students' concerns about physics. fear of experiments, enhance their self-efficacy, and promote students' in-depth understanding of physical phenomena and laws. However, research has also found that overreliance on desktop virtual reality activities may undermine students' ability to design rigorous experiments based on real equipment.
Transnationalism and Its Impact on the Creation of Collective Agency: The Case of Korean Military Brides in a Korean Immigrant Church in the U.S
Authors: Han Daehoon 
Published: December 2024

Literature on contemporary immigrants suggests that increasing transnational practices foster agency construction across borders, thereby disjoining geographical space and social space in which identities are constructed and negotiated. While studies pay increasing attention to the linkage between the transnational organizing of economic, political, and cultural activities among immigrant groups with a high level of transnationalism, relatively less attention has been given to the identity construction of immigrant groups without a high level of transnationalism. This study examines the agency dynamics among non-mobile immigrants who develop their agency by creating and negotiating boundaries through identity management practices in the wave of transnationalism that occurs in an immigrant church. Based on focus group interviews with fifteen Korean military brides and participant observation in a Mid-Western Korean immigrant church, the study revealed that through a new social space, Korean military brides not only created a more exclusive, closed, and homogeneous community within a Korean community, but their community becomes broader with comprehensive "imagined communities." This study also suggested that as non-mobile transnational immigrants, this effort is part of their gradual adaptation as well as resistance to assimilation to the wave of transnationalism that makes Korean immigrant communities in the U.S. noticeably transform various structural transformations.
Induction of cardiac alternans in human iPS‐derived cardiomyocytes through β‐adrenergic receptor stimulation
Authors: Hinata Yuto , Sasaki Daisuke , Matsuura Katsuhisa , Shimizu Tatsuya 
Published: December 2024

AbstractCardiac alternans (C‐ALT) is a phenomenon of alternating strong and weak contractions in the heart and is considered a risk factor for the development of heart failure and arrhythmias. However, no model has been reported that can induce C‐ALT in vitro using human cells, and the developmental mechanism of C‐ALT has not been studied using human cells. In this study, we successfully induced C‐ALT in vitro using human‐induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs). By stimulating β‐adrenergic receptor with isoproterenol on hiPSC‐CMs cultured in atmospheric condition (with ~0.04% CO2), contractility and calcium transient were observed to alternately increase and decrease with each beat. In contrast, C‐ALT was not induced in hiPSC‐CMs cultured at 5% CO2 concentration. Since previous studies have linked C‐ALT to problems with calcium regulation in the sarcoplasmic reticulum (SR), we exposed hiPSC‐CMs to compounds that alter SR Ca2+ loading and analyzed their contractile responses. The results showed that exposure to verapamil, thapsigargin, and ryanodine either suppressed or eliminated C‐ALT. In contrast, omecamtiv mecarbil and blebbistatin, which alter contractility without SR Ca2+ loading, did not induce or suppress C‐ALT. These results suggest that C‐ALT in hiPSC‐CMs induced by isoproterenol may be due to abnormal regulation of the ryanodine receptor's opening and closing caused by excessive Ca2+ load in the SR from β‐adrenergic receptor stimulation.
Detection of seepage zones in artificial levees: A case study at the Körös River, Hungary
Authors: Abdelsamei Enas , Tímár Attila , Sheishah Diaa , Blanka-Végi Viktória , Hegyi Alexandru , Runa Boglárka , Balogh Olivér , Ali Ahmed M. , Sipos György 
Published: December 2024

Abstract
This study evaluates the impact of seepage on the integrity of artificial levees in low-lying regions, with a particular focus on Hungary, where levees built over a century ago lack comprehensive construction documentation, complicating current assessments of their effectiveness. Advanced geophysical methods – electrical resistivity tomography (ERT) and ground-penetrating radar (GPR) – were applied in a controlled tank experiment designed to simulate varied flood conditions along a 37-m levee section. The three-dimensional (3D) ERT profiles successfully delineated seepage pathways as the tank filled, while the 3D GPR profiles indicated areas of increased amplitude, corresponding to seepage zones and the water table. Validation through drilling confirmed the geophysical findings, underscoring the accuracy of ERT and GPR in non-destructively identifying subsurface features and seepage channels. The results highlight the applicability of these methods for evaluating levee integrity and seepage dynamics, offering a reliable approach for flood risk assessment in Hungary and similar flood-prone areas worldwide.
Маршрутизация маневрового локомотива на путях необщего пользования для формирования грузовых составов с учетом обработки блокирующих вагонов
Authors: Васильев Юрий Михайлович , Глазунова Екатерина Валерьевна , Фридман Григорий Морицович 
Published: December 2024

Предмет: Одной из основных задач управления на железнодорожных путях необщего пользования является сбор грузовых вагонов на выделенных путях с целью формирования состава, предназначенного к отправке со станции. Оптимизационная математическая модель позволит автоматизировать этот процесс и повысить эффективность и рациональность решений, принимаемых транспортными диспетчерами. Цель: Статья посвящена формированию математической постановки для задачи сборки грузовых составов на путях необщего пользования железнодорожной станции ветвистого типа при помощи маневрового локомотива. Метод: Модель разработана на базе методов и подходов к поиску точного решению задач многокритериальной целочисленной оптимизации. Результаты: Апробация модели выполнена на синтетических исходных данных для выделенного участка железнодорожных путей ветвистой грузовой станции. Полученные числовые результаты демонстрируют возможность использования модели для решения поставленной задачи за приемлемое время.
Собственные источники финансирования организации
Authors: Ткачук Наталья Викторовна 
Published: December 2024

Предмет. Информация об источниках финансирования организации необходима внутренним и внешним пользователям. В отечественной экономической литературе отсутствует согласованность в трактовке состава собственных источников финансирования организации (собственном капитале). Объектом исследования выступает собственный капитал, как собственный источник финансирования организации, а предметом – состав собственных источников финансирования. Цели. Целью исследования является обоснование состава собственных источников финансирования организации. Задачи исследования: показать роль информации о собственном капитале как собственном источнике финансирования организации; обобщить позиции ученых о содержании собственных источников финансирования организации; определить факты хозяйственной жизни, влияющие на величину собственного капитала организации; выделить внешние и внутренние источники формирования собственного капитала организации. Методология. В процессе достижения поставленных целей использовались методы научного познания: диалектический; анализа и синтеза. Исследование построено на изучении международных стандартов финансовой отчётности, федеральных стандартах по бухгалтерскому учету, актуальной научной экономической литературы. Выводы. Определена информация о величине собственного капитала, необходимая внешним пользователям для принятия решений инвестиционного и контрагентского характера. Выделены группы фактов хозяйственной жизни, оказывающие влияние на величину собственного капитала организации. Определены внешние и внутренние источники формирования собственного капитала.
A comparative study of albumin bilirubin score, with meld for predicting the in-hospital mortality in cirrhotic patients complicated with upper gastrointestinal bleeding in a tertiary care hospital
Authors: Prajapati Parmendra Kumar , Priyadarshi Basudev Prasad , Dar Ashaq Hussain 
Published: December 2024

Background: Chronic liver disease (CLD) encompasses a spectrum of injury from simple steatosis to frank cirrhosis which is evaluated by many scoring systems. Aim of the study was to evaluate the discriminative abilities of model for end-stage liver disease (MELD) score and albumin-bilirubin (ALBI) score in predicting the in-hospital mortality in cirrhotic patients complicated with upper gastrointestinal bleeding.
Methods: Data of patients with liver cirrhosis secondary to ethanol, hepatitis B and hepatitis C and cryptogenic liver cirrhosis, with upper gastrointestinal bleed was prospectively reviewed from admission to date of discharge. MELD and ALBI score, calculated for the patient from ROC curves were analysed.
Results: Our study was conducted on 149 patients. Age distribution was between 18-80 years with mean age of patients being 44.7±12.37 years, male to female sex ratio 127:22, with mortality calculated at 23.5%. The MELD score demonstrated a high predictive accuracy with an area under ROC curve of 0.953, with a 95% confidence interval ranging from 0.903 to 1.000. In contrast, ALBI score showed a lower predictive accuracy with an area under the ROC curve (AUROC) of 0.672 and 95% confidence interval ranging from 0.577 to 0.766.
Conclusions: The prognostic performance of two scores was comparable but MELD score was found to have a better prognostic significance than ALBI score.
Assessing the effectiveness and NSAIDs sparing effect of celery seeds and Boswellia serrata in osteoarthritis management
Authors: Nair Sreeni , Desai Anish , Anand Sunaina , Chorghe Parita 
Published: December 2024

: This study examines the anti-inflammatory and analgesic properties of Celery seed and extracts as potential alternatives for OA treatment, focusing on their effectiveness in reducing pain and improving joint functionality.Osteoarthritis (OA), a prevalent joint disorder, particularly affects the knees and hips. Current management primarily involves NSAIDs, which can lead to severe side effects, especially in older adults with comorbidities. A multicentre observational study enrolled 394 participants clinically diagnosed with knee osteoarthritis. They continued their usual treatment while taking Celery seeds and extract tablet twice daily for three months. Primary outcomes included Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores and changes in painkiller and NSAID usage. Secondary outcomes included visual analogue scale (VAS) pain scores.The study demonstrated significant improvements in primary outcome measures: WOMAC score improved by 17.07% (p&#60;0.001), WOMAC pain score by 75.00% (p&#60;0.001), WOMAC stiffness score by 72.05% (p&#60;0.001) and WOMAC physical function score by 78.93% (p&#60;0.001). Secondary outcomes showed VAS score reductions at rest by 67.17% (p&#60;0.001) and during movement by 64.28% (p&#60;0.001). There was a notable decrease in NSAID usage from baseline 70.09% to 31.89% (p&#60;0.001).Celery seeds and extract demonstrate promising efficacy as a safer and effective adjunctive therapy for knee osteoarthritis, offering pain relief, enhanced joint functionality and potential reduction in NSAID usage.
A prospective study to evaluate the outcome of periarthritis shoulder treated with platelet rich plasma
Authors: Yadav Vinod Ramlal , Ravindran Biju , Vardhan N Vishnu , Jyothsna Rachuru Venkata 
Published: December 2024

Periarthritis shoulder also called as Adhesive capsulitis or Frozen shoulder. The body creates excessive adhesion across the glenohumeral joint as a result of the idiopathic, chronic, and indolent degenerative process known as periarthritis shoulder, which causes discomfort, stiffness, and a reduction in range of motion. In the general population, the prevalence of adhesive capsulitis is 3-55%, and it is 20% in those with diabetes. Many types of treatment have been employed in the treatment of shoulder disorder such as simple analgesia, NSAIDS, intraarticular steroid, platelet rich plasma injection and surgery. PRP is more efficient and long-lasting than cortisone injection for the treatment of adhesive capsulitis, according to several research.To evaluate the outcome of Periarthritis shoulder treated with Platelet Rich Plasma by comparing the intensity of pain, degree of increase in angle of movements of shoulder.It is a randomized control trial with total of 30 patients between age group of 30–70 years old of both sex being diagnosed for the first time and not treated by any other modality are taken up for the study.Patients having chronic pain due to other causes like nerve damage or other neurological disorders, history of fracture around the shoulder joint, patients having local skin infection at the shoulder joint and patient not giving informed consent form to be a part of study were excluded from the study. Under sterile aseptic condition Autologous Platelet Rich Plasma of 4 ml was injected into the shoulder joint. It was a randomized single blinded controlled trial with 1 month, 3 months & 6 months follow up in which outcome was measures using visual analogue scale, ROM, SPADI.Using the paired t test, descriptive and inferential statistical analysis were performed inthe current study. The mean VAS score at 6 months was reduced from 6.66+2.499 to 3.4±1.473; Mean SPADI Score at 6 month increased from 50.53±14.811 to 76.76±10.926; At 6 month Flexion increased from 66 to 116.33, extension increased from 18.6 to 31.33 and abduction increased from 87.33 to 126.833 with p value of 0.0001 which is statistically significant.This study concluded that platelet rich plasma injection causes decrease in intensity of pain and increase in angle of movements of shoulder in patients of periarthritis shoulder.
Limb occlusion pressure as a tool to optimize the tourniquet pressure in total knee arthroplasty without compromising the creation of a bloodless surgical field
Authors: Reddy Thirumalesh K , Malchira Somanna 
Published: December 2024

: Pneumatic tourniquet is utilized in orthopedic surgery to create a bloodless field. Limb Occlusion Pressure (LOP) is the minimum pressure required at a specific time and location to halt arterial blood flow distal to the cuff. : The purpose of this study is calculation of the minimum possible tourniquet pressure using LOP to significantly reduce tourniquet pressure in Total knee arthroplasty surgery without compromising the creation of a bloodless surgical field.: This study included 200 patients who underwent primary total knee arthroplasty. Tourniquet pressure was set based on Limb occlusion pressure measured just before the surgery. After the surgery, surgeon was asked to rate the quality of the bloodless field on a visual analog scale, and look for post-operative complications like, tourniquet site pain, injury to skin, redness, blisters, flaring, neurological symptoms. tourniquet palsy and chemical burns. The average LOP was 163.65mmHg and average tourniquet pressure was 221.15mmHg. The minimum tourniquet pressure we used was 140mmHg. The quality of bloodless field was excellent in 88% patients. 6 patients (3%) had redness at the skin and 5 patient had tourniquet site pain. None of the patients had chemical burns, injury to skin, blisters or tourniquet palsy.: This new tourniquet technique based on Limb occlusion pressure (LOP), is an effective device for maintaining a bloodless surgical field in orthopedic limb surgery. By reducing tourniquet pressure, this method lowers the frequency and severity of pressure-related complications. The LOP estimation method is simple, quick, and effective, making it feasible for broader clinical use. It ensures safer, personalized cuff pressures for tourniquet applications in limb surgery.
Outcome of distal radius fractures managed conservatively and with percutaneous pinning (k-wires): A comparative study
Authors: Ahmed Shorifuddin , Bala Prabir Kumar , Mishra Hriday Narayan 
Published: December 2024

Distal radius fractures are frequent injuries to the upper limbs that can be treated conservatively or surgically using K-wire percutaneous pinning. In order to restore anatomical alignment, percutaneous pinning is a more invasive approach than conservative therapy, which usually consists of splinting or casting. : This study aims to analyze the clinical and radiological outcome of distal radius fractures managed with closed reduction and plaster cast immobilization (CRPCI) and with closed reduction and percutaneous pinning (CRPP).: The present study is an Institutional based prospective comparative study comprised of total 50 adult patients between 20 to 65 years of age, with distal end radius fractures attending Out Patients Department or Emergency at the Department of orthopaedics, Medical College, Kolkata, India. Among them 25 patients were treated with CRPCI and 25 patients treated with CRPP with K-wire who fulfil the study criteria, during the period January 2021 to June 2022, the study was conducted for 18 months. Cases were evaluated based on the criteria of Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire score, VAS score, wrist range of motion, and radiologic results.: The age of patients in this series ranged from (20-65) years with maximum patients (72%) in the (51-65) years age group, majority of the patients were female 66%. Among the radiographic parameters in Radial Inclination, Radial Height, and Ulnar Variance there were statistically significant (p-value&#60;0&#62;0.05) differences are noted in wrist dorsiflexion,palmar flexion, pronation, supination, ulnar deviation and radial deviation in degree between two group. Functional assessment by DASH score (p-value 0.90), VAS score (p-value 0.59) show both have p-values&#62;0.05 which are statistically insignificant between two groups.: In this era where operative intervention is commonly practiced for distal radius fracture treatment. we concluded that despite the study showing poor radiographic outcomes associated with CRPCI than CRPP in terms of functional outcomes there were no differences between the two treated groups.
A prospective study on the functional and radiological outcome of suprapatellar and infrapatellar intramedullary nailing for proximal tibia extra-articular fractures
Authors: Singh Abhishek , Gupta Gagandeep , Singh Navneet , Kala Shivang , Sood Suraj , Saini Akhilesh , Singh Shristi , Shende Sopan 
Published: December 2024

The most effective therapy for proximal tibia extra-articular fractures, which are among the most frequent long bone fractures, is intramedullary nailing. With each technique offering distinct benefits and disadvantages, the decision between suprapatellar and infrapatellar techniques for intramedullary nailing is still up for debate. The purpose of this study is to compare the radiological and functional results of these two methods. The aim of this study is to compare the functional and radiological outcomes of suprapatellar and infrapatellar intramedullary nailing techniques in the management of proximal tibia extra-articular fractures. In this randomized controlled research, 40 patients with proximal tibia extra-articular fractures were randomized to either the Infrapatellar group (n = 20) or the Suprapatellar group (n = 20). At 1, 3 and 6 months following surgery, the Lower Extremity Functional Scale (LEFS) and the Lysholm Knee Score were used to evaluate functional outcomes. The Visual Analog Scale (VAS) was used to gauge pain levels and radiographic results were evaluated for alignment and fracture healing. T-tests and other statistical analyses were used to compare the groups. The functional outcomes at 3 and 6 months after surgery were noticeably better for the suprapatellar group. The Suprapatellar group's Lysholm Knee Score at 6 months was substantially higher (92.2 ± 5.35) than that of the Infrapatellar group (87.95 ± 5.34, p = 0.016). Similarly, the Suprapatellar group had a higher LEFS score at 6 months (88.20 ± 4.54) than the Infrapatellar group (82.10 ± 5.86, p = 0.025). Additionally, the Suprapatellar group experienced less discomfort, with a mean VAS score of 2.0 (±0.30) being lower than the Infrapatellar group's 2.50 (±0.50) (p = 0.001). When treating proximal tibia extra-articular fractures, this study shows that suprapatellar nailing produces better functional outcomes with reduced pain than infrapatellar nailing. These results suggest that the Suprapatellar method is a better choice for treating proximal tibia extra-articular fractures.
Tumor to triumph: bone reconstruction with extracorporeal irradiation in malignant bone tumors
Authors: Sharma Hardik , Bhatia Shruti Kant , Rawal Kushal 
Published: December 2024

Malignant bone tumors (MBTs) are predominantly seen in children and adolescents and account for &#60;1% of diagnosed cancers each year. This case study demonstrates how ECI acts as a limb salvage method for MBT, particularly in low-income settings. A 17yr old male patient present pain & swelling around left ankle for 1 year. The radiograph showed lytic lesion in the left distal fibula followed by biopsy suggestive of osteosarcoma. Patient underwent four cycle of Adriyamycin based chemotherapy followed by wide local excision with extracorporeal irradiation. The patient also received four cycles of adjuvant chemotherapy. Now, patient was free of disease and on regular follow-up. By delivering high-dose radiation directly to affected bone ECI helps to minimize damage to surrounding healthy areas. It also offers significant therapeutic advantages, including enhanced tumor control and the preservation of limb functionality. As technology and techniques continue to evolve, ECI may play an important role in treating cancers that are challenging to manage with conventional therapies.