bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors
Authors: Wang Yu , Voliotis Aristeidis , Shao Yunqi , Zong Taomou , Meng Xiangxinyue , Du Mao , Hu Dawei , Chen Ying , Wu Zhijun , Alfarra M. Rami , McFiggans Gordon 
Published: July 2021

Abstract. The phase behaviour of aerosol particles plays a profound role in atmospheric physicochemical processes, influencing their physical and optical properties and further impacting climate and air quality. However, understanding of the aerosol phase state is still incomplete, especially that of multicomponent particles which contain inorganic compounds and secondary organic aerosol (SOA) from mixed volatile organic compound (VOC) precursors. We report measurements conducted in the Manchester Aerosol Chamber (MAC) to investigate the aerosol rebounding tendency, measured as the bounce fraction, as a surrogate of the aerosol phase state during SOA formation from photo-oxidation of biogenic (α-pinene and isoprene) and anthropogenic (o-cresol) VOCs and their binary mixtures on deliquescent ammonium sulfate seed. Aerosol phase state is dependent on relative humidity (RH) and chemical composition (key factors determining aerosol water uptake). Liquid (bounce fraction; BF < 0.2) at RH > 80 % and nonliquid behaviour (BF > 0.8) at RH < 30 % were observed, with a liquid-to-nonliquid transition with decreasing RH between 30 % and 80 %. This RH-dependent phase behaviour (RHBF=0.2,0.5,0.8) increased towards a maximum, with an increasing organic–inorganic mass ratio (MRorg/inorg) during SOA formation evolution in all investigated VOC systems. With the use of comparable initial ammonium sulfate seed concentration, the SOA production rate of the VOC systems determines the MRorg/inorg and, consequently, the change in the phase behaviour. Although less important than RH and MRorg/inorg, the SOA composition plays a second-order role, with differences in the liquid-to-nonliquid transition at moderate MRorg/inorg of ∼1 observed between biogenic-only
(anthropogenic-free) and anthropogenic-containing VOC systems. Considering the combining role of the RH and chemical composition in aerosol phase state, the BF decreased monotonically with increasing hygroscopic growth factor (GF), and the BF was ∼0 when GF was larger than 1.15. The real atmospheric consequences of our results are that any processes changing ambient RH or MRorg/inorg (aerosol liquid water) will influence their phase state. Where abundant anthropogenic VOCs contribute to SOA, compositional changes in SOA may influence phase behaviour at moderate organic mass fraction (∼50 %) compared with purely biogenic SOA. Further studies are needed on more complex and realistic atmospheric mixtures.
Avaliação da implantação dos núcleos hospitalares de epidemiologia
Authors: Oliveira Adélia Dalva Da Silva , Andrade Jesusmar Ximenes , Guimarães Maria do Socorro Oliveira , Da Silva Telma Maria Evangelista , Mascarenhas Márcio Dênis Medeiros 
Published: July 2021

RESUMO Objetivo: avaliar a implantação dos Núcleos Hospitalares de Epidemiologia. Método: trata-se de estudo quantitativo, descritivo, avaliativo, do tipo normativo. Realizou-se em nove núcleos hospitalares de Epidemiologia. Obtiveram-se os dados por meio de questionário autoaplicável e formulário. Apresentaram-se os resultados em forma de tabelas. Resultados: agruparam-se os resultados em matriz de julgamento e o somatório dos pontos obtidos determinou a adequação da implantação. Conclusão: constatou-se, pelo estudo, que a implantação dos Núcleos Hospitalares de Epidemiologia, não ocorreu de forma satisfatória. Descritores: Vigilância Epidemiológica; Hospital; Serviços de Saúde; Enfermagem; Epidemiologia; Pesquisa Sobre Serviços de Saúde.ABSTRACT Objective: to evaluate the implantation of the Hospital Epidemiology Centers. Method: this is a quantitative, descriptive, evaluative, normative study. It was carried out in nine hospital centers of Epidemiology. The data was obtained through a self-administered questionnaire and form. Results were presented in the form of tables. Results: the results were grouped in the trial matrix and the sum of the points obtained determined the adequacy of the implantation. Conclusion: It was verified, by the study, that the implantation of the Hospital Epidemiology Centers, did not occur in a satisfactory way. Descriptors: Epidemiological Surveillance; Hospital; Health services; Nursing; Epidemiology; Health Services Research.RESUMEN Objetivo: evaluar la implantación de los Núcleos Hospitalarios de Epidemiología. Método: se trata de estudio cuantitativo, descriptivo, evaluativo, del tipo normativo. Se realizó en nueve núcleos hospitalarios de Epidemiología. Se obtuvieron los datos por medio de cuestionario autoaplicable y formulario. Se presentaron los resultados en forma de tablas. Resultados: se agruparon los resultados en matriz de juicio y la suma de los puntos obtenidos determinó la adecuación de la implantación. Conclusión: se constató, por el estudio, que la implantación de los Núcleos Hospitalarios de Epidemiología, no ocurrió de forma satisfactoriaDescriptores: Monitoreo Epidemiológico; Hospital; Servicios de Salud; Enfermería; Epidemiología; Investigación em Servicios de Salud.
SISTEM INFORMASI PEMANTAUAN PEMBUATAN POLIS ASURANSI
Authors: Immasari Ito Riris , Prasetyo Aditya 
Published: July 2021

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Pembuatan polis di PT Asuransi Adira Dinamika, Tbk, Departement Operational Centre Policy yang berjalan saat ini belum memanfaatkan teknologi informasi secara maksimal. Untuk mengatasi masalah tersebut maka diperlukan Perancangan Sistem Informasi Pemantauan Pembuatan Polis Asuransi di PT Asuransi Adira Dinamika Tbk Departement Operational Centre Policy dengan menggunakan basis data Mysql. Metode yang digunakan metode pendekatan sistem dan pengembangan sistem sehingga mempermudah pengelolaan data laporan yang dibutuhkan menjadi lebih cepat, lengkap dan tepat. Metode perancangan yang digunakan adalah pendekatan sistem dengan pemodelan UML (Unfied Modelling Language) dan diimplementasikan dengan bahasa pemrograman PHP dan MySQL sebagai basis data. Sedangkan metode pengembangan perangkat lunat yang digunakan adalah model Waterfall. Adapun saran yang diberikan adalah merancang sistem informasi order polis baru yang dapat meningkatkan kualitas pengelolaan data lebih akurat dan cepat serta mengadakan perawatan sistem secara rutin
Répartitions spatiale et temporelle des feux à Madagascar
Authors: Hasina Andriamanantena Heninjara Narovana , Rakotondraompiana Solofo , Rakotoniaina Solofoarisoa , Razanaka Samuel 
Published: July 2021

Cette publication participe à la compréhension de la dégradation de l’environnement à Madagascar. Spécifiquement, il s’agit d’analyser la distribution spatiale et temporelle des feux à Madagascar et d’identifier les facteurs à l’origine des feux. Les données fournies par le capteur MODIS sur l’ensemble du territoire de Madagascar pour les années 2014 à 2018 sont utilisées. Les résultats obtenus indiquent une certaine stabilité des points de feux actifs observés à Madagascar pendant la période 2014 à 2018, sauf pour l’année 2016, année de forte sécheresse mondiale. Les feux brûlent en moyenne une superficie de 3 757 792 ha par an. La majorité de ces feux est observée pendant la saison sèche et leur maximum en nombre et en superficie est atteint aux mois de septembre et octobre. Au premier abord, les feux couvrent la quasi-totalité du pays. Toutefois, les analyses spatiales et temporelles montrent que les points de feu sont regroupés en agrégats d’ordre 1, 2, 3 ou 4. Les agrégats indiquent les zones où l’on retrouve une concentration de points de feux. Les régions contenant des agrégats d'ordres supérieurs sont les plus exposées. Ce sont des zones auxquelles il est nécessaire d’accorder une attention particulière. Les résultats de l’analyse par permutation spatio-temporelle indiquent que les feux proches dans l’espace le sont aussi dans le temps. La répartition des agrégats par rapport aux pistes et aux villages démontre que les feux se propagent essentiellement à proximité des lieux habités et des voies d’accès.
Wim Wenders’ Wings of Desire: Anticipating Uberveillance
Authors: Michael M. G. , Michael Katina , Bookman Terri 
Published: July 2021

Abstract
This article uses Wim Wenders’ romantic fantasy film Wings of Desire (1987) to contrast the roles of angels with uberveillance. Varying points of view are considered in the surveillance spectrum, demonstrating that while we can artificially fabricate omnipresence, omniscience still belongs to the heavenly realm. Humans will continue to encroach on personal privacy through the latest technological exploits penetrating the human within, while the angels will stand by their limitations acknowledging their role as listeners but not intruders. This article acts as a reminder of the intrinsic worth of human life in synergy with love, beyond the quantification of advanced technologies that seek to decorporealize and propel us to gamify our existence. What is important? It is the human connection; the ability to hold out our hand to another and have it clasped in reciprocity. This will reunify the world faster in compassion than any other technological marvel thrust upon us.
Prevalence and Causes of Low Vision and Blindness among Adult Patients Attending Eye Clinic in a Tertiary Hospital in South East, Nigeria
Authors: Otuka O. A. I. , Ekeleme N. C. , Akaraiwe E. N. , Iwuoha E. C. , Eweputanna L. I. , Kalu A. 
Published: July 2021

Background: Low vision and blindness are significant public health issues worldwide. They result in educational, occupational, and social challenges in the affected persons. Their care givers/ families are also severely affected. There is however limited data on the magnitude of visual impairment in Aba, South East Nigeria.
Objective: To determine the prevalence and causes of low vision and blindness among adult patients attending eye clinic in a tertiary hospital in South East Nigeria.
Materials and Methods: This was an institutional-based retrospective, descriptive study involving 457 patients who attended Abia State University Teaching Hospital eye clinic between April and September 2018. Data was obtained from patient’s hospital records within the period under study and analyzed using IBM SPSS version 25.0. Statistical significance was set at a P-value of < 0.05.
Results: Data of 457 ophthalmic patients who met the inclusion criteria for this study were analyzed. Mean age of respondents was 48.5 ± 17.7 years. A total 5.4% of the patients had bilateral low vision, while 30.2% and 7% had monocular and bilateral blindness respectively. Cataract-related diagnosis, refractive errors and glaucoma (28.4%, 28.2% and 14.7%) respectively were the major causes of low vision and blindness among the patients. Statistically significant association was found between respondent’s diagnosis and age as well as occupation (P<0.001).
Conclusion: Results from this study will aid in planning low vision & blindness preventive programs and improving eye care services.
The Utilization of Mg-Al/Cu as Selective Adsorbent for Cationic Synthetic Dyes
Authors: Badri Arini Fousty , Palapa Neza Rahayu , Mohadi Risfidian , Mardiyanto Mardiyanto , Arsyad Fitri Suryani , Lesbani Aldes 
Published: July 2021

Mg-Al-LDH is a chemical compound produced through co-precipitation technique and modified with Cu(NO3)2.6H2O to form Mg-Al/Cu. However, the research on the capability of these compounds for adsorbing mixtures of cationic dyes as well as malachite green (MG), methylene blue (MB), and Rodhamine-B (Rh-B) has not been carried out. Therefore, this research aims to determine the performance of Mg-Al-LDH and Mg-Al/Cu for removing cationic dyes. The materials used were characterized by using XRD powder, FT-IR, and N2 adsorption desorption. The Adsorption process was conducted by batch system and several effects were investigated, such as kinetic parameter, isotherm, and the temperature condition. The stability feature of Mg-Al-LDH and Mg-Al/Cu was obtained from the regeneration process in the five cycles. The results presented that Mg-Al/Cu was effectively produced, which was indicated by the formation of layer at 10.792° (003), 22.94° (006), 35.53° (112), 55.78° (110), and 56.59° (116). Mg-Al-LDH and Mg-Al/Cu were found to adsorbed MG than the other cationic dyes with adsorption capacity of 68.996 mg/g and 104.167 mg/g, respectively. The unique properties of Mg-Al/Cu includes, structural stability towards the reuse of adsorbent subsequently for five times, without significant decrease of adsorption capacity. Copyright © 2021 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
Nanopoxia: Targeting Cancer Hypoxia by Antimonene‐Based Nanoplatform for Precision Cancer Therapy
Authors: Qiu Meng , Duo Yanhong , Liang Weiyuan , Yang Yunlong , Zhang Bin , Xie Zhongjian , Yang Xiaoli , Wang Guiqing , Xie Ni , Nie Guohui , Alhartomy Omar A. , ALGhamdi Ahmed A. , Wageh Swelm , Cao Yihai , Zhang Han 
Published: July 2021

AbstractMost anticancer drugs with broad toxicities are systematically administrated to cancer patients and their distribution in tumors is extremely low owing to hypoxia, which compromises the therapeutic efficacies of these cancer drugs. Consequently, a preponderant proportion of cancer drugs is distributed in off‐target‐healthy tissues, which often causes severe adverse effects. Precision cancer therapy without overdosing patients with drugs remains one of the most challenging issues in cancer therapy. Here, a novel concept of nanopoxia is presented, which is a tumor‐hypoxia‐based photodynamic nanoplatform for the release of therapeutic agents to achieve precision cancer therapy. Under tumor hypoxia, exposure of tumors to laser irradiation induces the fracture of polymer outer shell and produces anticancer reactive oxygen species, and switches 2D antimonene (Sb) nanomaterials to cytotoxic trivalent antimony to synergistically kill tumors. In preclinical cancer models, delivery of Sb nanomaterials to mice virtually ablates tumor growth without producing any detectable adverse effects. Mechanistically, the tumor hypoxia‐triggered generation of trivalent antimony displays direct damaging effects on cancer cells and suppression of tumor angiogenesis. Together, the study provides a proof‐of‐concept of hypoxia‐based precision cancer therapy by developing a novel nanoplatform that offers multifarious mechanisms of cancer eradication.
Self‐Cycling Free Radical Generator from LDH‐Based Nanohybrids for Ferroptosis‐Enhanced Chemodynamic Therapy
Authors: Yang Xueting , Wang Li , Guo Shuaitian , Li Ran , Tian Fangzhen , Guan Shanyue , Zhou Shuyun , Lu Jun 
Published: July 2021

AbstractNonapoptotic ferroptosis has been a novel form of programmed cell death, which provides a new solution to enrich the anticancer treatment efficacy of traditional apoptotic therapeutic modality. Herein, a novel nanohybrid is designed by loading the PEG‐encapsulated Artemisinin (denoted as A@P) on the ultrathin MgFe‐LDH nanosheets (denoted as uLDHs) for improved chemodynamic therapy (CDT). The A@P/uLDHs cannot only realize the self‐assembly between the Art and carrier but also be regarded as free radical generator. A comprehensive mechanistic study suggests that this unique A@P/uLDHs is able to in situ activate Art and self‐cycling generate toxic C‐centered free radical inside the cancer cells, without depending on abundant H2O2, accompanied with diminished cancerous antioxidation by depleting glutathione (GSH). The accumulation of ROS and depletion of GSH can further oxidize unsaturated fatty acid to generate lipid peroxide, whose overexpression can induce cell ferroptosis accompanied by cellular iron homeostasis turbulence. Both in vitro and in vivo results exhibit that A@P/uLDHs are an efficient nanoagent for highly efficient ferroptosis‐enhanced CDT treatment. This work imparts the promising new visions about the ferroptosis‐enhanced CDT via fine regulation of material design for improved cancer treatments.
Aggregation‐Induced Emission (AIE) Nanoparticles‐Assisted NIR‐II Fluorescence Imaging‐Guided Diagnosis and Surgery for Inflammatory Bowel Disease (IBD)
Authors: Fan Xiaoxiao , Xia Qiming , Zhang Yiyin , Li Yirun , Feng Zhe , Zhou Jing , Qi Ji , Tang Ben Zhong , Qian Jun , Lin Hui 
Published: July 2021

AbstractThe incidence of inflammatory bowel diseases (IBD), including Crohn's diseases and ulcerative colitis, is increasing by time and showing a trend of younger age. Precise diagnosis and effective treatments for IBD have attracted growing attention in recent years. However, diagnosing and locating inflammatory lesions remain a great challenge for IBD. In this study, assisted by a kind of aggregation‐induced emission (AIE) nanoprobes (BPN‐BBTD nanoparticles [NPs]), the second near‐infrared (NIR‐II) fluorescence imaging is first utilized to accurately trace inflammatory lesions, monitor inflammation severity and detect the response to the drug intervention in IBD mouse models. Through the advantages of high signal‐to‐background ratio (SBR) and sharp spatial resolution of bio‐imaging in NIR‐II region, the NIR‐II fluorescence imaging‐guided surgery can help to achieve a complete resection of severe inflammatory bowls and a secure surgical anastomosis. In addition, with the help of NIR‐II fluorescence wide‐field microscopy, the distribution of BPN‐BBTD NPs can be directly detected in tissue level and found to be mainly accumulated in mucosa and submucosa layers. This study highlights that AIE NPs‐assisted NIR‐II fluorescence imaging hold a great potential value for future diagnosis and imaging‐guided surgery in IBD.
Auto Tandem Catalysis: Asymmetric Vinylogous Cycloaddition/Kinetic Resolution Sequence for the Enantioselective Synthesis of Spiro‐Dihydropyranone from Benzylidene Meldrum's Acid
Authors: Toffano Martial , Guillot Régis , Bournaud Chloée , Brière Jean‐François , Vo‐Thanh Giang 
Published: July 2021

AbstractA catalytic enantioselective vinylogous domino reaction has been achieved from ketone‐derived benzylidene Meldrum's acid and α‐ketolactones to provide spirolactone dihydropyranones with more than 99% ee. An Auto Tandem Catalysis (ATC) process resulting from dual and complementary role of (DHQ)2PHAL organocatalyst resulted in a sequence involving an asymmetric vinylogous formal (4+2) cycloaddition of benzylidene and the subsequent kinetic resolution operating through a 1,3‐prototropic shift leading to good yields (>50%) and the high selectivity.magnified image
Directing Transition of Synthetic Protocell Models via Physicochemical Cues‐Triggered Interfacial Dynamic Covalent Chemistry
Authors: Ji Yanglimin , Mu Wenjing , Wu Hua , Qiao Yan 
Published: July 2021

AbstractAs the preliminary synthetic analogs of living cells, protocells with life‐like features serve as a versatile platform to explore the origin of life. Although protocells constructed from multiple components have been developed, the transition of primitive cellular compartments toward structural complexity and advanced function remains a scientific challenge. Herein, a programmable pathway is established to exploit a simple chemistry to construct structural transition of protocell models from emulsion droplets, nanocapsules to molecularly crowded droplets. The transitional process toward distinct cell‐like compartments is driven by interfacial self‐assembly of simple components and regulated by physicochemical cues (e.g., mechanical force, solvent evaporation, acid/base equilibrium) triggered dynamic covalent chemistry. These protocell models are further studied by comparing their compartmentalization behavior, sequestration efficiency, and the ability to enrich biomolecules (e.g., enzyme and substrate) toward catalytic reaction or biological activity within the compartments. The results showcase physiochemical cues‐driven programmable transition of life‐like compartments toward functionalization, and offer a new step toward the design of living soft materials.
Integration of Colloidal Quantum Dots with Photonic Structures for Optoelectronic and Optical Devices
Authors: Chen Mengyu , Lu Lihua , Yu Hui , Li Cheng , Zhao Ni 
Published: July 2021

AbstractColloidal quantum dot (QD), a solution‐processable nanoscale optoelectronic building block with well‐controlled light absorption and emission properties, has emerged as a promising material system capable of interacting with various photonic structures. Integrated QD/photonic structures have been successfully realized in many optical and optoelectronic devices, enabling enhanced performance and/or new functionalities. In this review, the recent advances in this research area are summarized. In particular, the use of four typical photonic structures, namely, diffraction gratings, resonance cavities, plasmonic structures, and photonic crystals, in modulating the light absorption (e.g., for solar cells and photodetectors) or light emission (e.g., for color converters, lasers, and light emitting diodes) properties of QD‐based devices is discussed. A brief overview of QD‐based passive devices for on‐chip photonic circuit integration is also presented to provide a holistic view on future opportunities for QD/photonic structure‐integrated optoelectronic systems.
The Hidden Side of Nanoporous β‐Li3PS4 Solid Electrolyte
Authors: Marchini Florencia , Porcheron Benjamin , Rousse Gwenaelle , Albero Blanquer Laura , Droguet Léa , Foix Dominique , Koç Tuncay , Deschamps Michael , Tarascon Jean Marie 
Published: July 2021

AbstractSolid‐state batteries are enjoying a regained interest owing to the discovery of sulfide‐based solid electrolytes with ionic conductivities comparable to their liquid counterparts. Among them, the metastable β‐Li3PS4 polymorph has attracted great attention given its high room temperature ionic conductivity (≈0.15 mS cm−1) when synthesized via a solvent‐mediated route. However, the origin of such a high conductivity together with its structural interplay remains unclear. Herein, an in‐depth study of the THF‐synthesized nanoporous β‐Li3PS4 is reported. Synchrotron X‐ray diffraction, NMR, and Raman spectroscopy confirm the presence of β‐Li3PS4 as the only crystalline phase and also reveal an additional amorphous phase and remnant THF. Moreover, a clear dependence of the ionic conductivity of the material on the relative content of its phases is found, the amorphous one being the most conductive. Lastly, high chemical reactivity is found for the nanoporous β‐Li3PS4 and other phosphosulfide electrolytes toward Li metal, evidenced in the spontaneous ignition when mixed together and further investigated by XRD and XPS. This study, which unveils a hidden side of the THF‐synthesized β‐Li3PS4 and other sulfide solid electrolytes, provides a new insight to the battery community when selecting a proper electrolyte for practical all‐solid state batteries.