bluuebunny/crossref_metadata_2025_split huggingface dataset:
Responsible Robotics and Responsibility Attribution
Authors: van Wynsberghe Aimee 
Published: February 2021

AbstractThis paper stresses the centrality of human responsibility as the necessary foundation for establishing clear robotics policies and regulations; responsibility not on the part of a robot’s hardware or software, but on the part of the humans behind the machines—those researching and developing robotics. Simply put, we need responsible robotics. Responsible robotics is a term that has recently ‘come into vogue’, yet an understanding of what responsible robotics means is still in development. In light of both the complexity of development (i.e. the many hands involved) and the newness of robot development (i.e. few regulatory boards established to ensure accountability), there is a need to establish procedures to assign future responsibilities among the actors involved in a robot’s development and implementation. The three alternative laws of responsible robotics by Murphy and Wood play a formidable contribution to the discussion; however, they repeat the difficulty that Asimov introduced, that is, laws in general, whether they are for the robot or for the roboticist, are incomplete when put into practice. The proposal here is to extend the three alternative laws of responsible robotics into a more robust framework for responsibility attribution as part of the responsible robotics goal. This framework requires making explicit various factors: the type of robot, the stage of robot development, the intended sector of use, and the manner of robot acquisition. With this in mind, one must carefully consider the scope of the ethical issue in question and determine the kind of responsibility attributed to said actor(s).
A Human Blueprint for AI Coexistence
Authors: Lee Kai-Fu 
Published: February 2021

AbstractThe positive coexistence of humans and AI is possible and needs to be designed as a system that provides for all members of society, but one that also uses the wealth generated by AI to build a society that is more compassionate, loving, and ultimately human. It is incumbent on us to use the economic abundance of the AI age to foster the values of volunteers who devote their time and energy toward making their communities more caring. As a practical measure, to protect against AI/robotics’ labor saving and job displacement effects, a “social investment stipend” should be explored. The stipend would be given to those who invest their time and energy in those activities that promote a kind, compassionate, and creative society, i.e., care work, community service, and education. It would put the economic bounty generated by AI to work in building a better society, rather than just numbing the pain of AI-induced job losses.
Robotics and the Global Organisation of Production
Authors: De Backer Koen , DeStefano Timothy 
Published: February 2021

AbstractThe growing investment in robotics is an important aspect of the increasing digitalisation of economy. Economic research has begun to consider the role of robotics in modern economies, but the empirical analysis remains overall limited. The empirical evidence of effects of robotics on employment is mixed, as shown in the review in this chapter. The effects of robots on economies go further than employment effects, as there are impacts for the organisation of production in global value chains. These change the division of labour between richer and poorer economies. Robotics may reduce offshoring of activities from developed economies towards emerging economies. Global spreading of automation with robotics can lead to faster de-industrialisation in the development process. Low-cost jobs in manufacturing may increasingly be conducted by robots such that fewer jobs than expected may be on offer for humans even if industries were to grow in emerging economies.
The effect of age on the outcomes of cementless mobile bearing unicompartmental knee replacements
Authors: Mohammad Hasan Raza , Mellon Stephen , Judge Andrew , Dodd Christopher , Murray David 
Published: February 2021

Abstract
Purpose
Unicompartmental Knee Replacements (UKR) are being performed in patients with increasing demands and life expectancies with surgical concerns that cemented fixation will not last. Cementless fixation may offer a solution, but the results in different age groups have not been assessed. The effect of age at surgery on the outcomes of cementless UKRs was investigated.

Methods
A prospective cohort of 1000 medial cementless mobile bearing UKR were analysed. Patients were categorised into four age groups (< 55, 55 to < 65, 65 to < 75 and ≥ 75 years). Implant survival was assessed using endpoints reoperation, revision and major revision requiring revision knee replacement components. Functional outcomes were assessed.

Results
10 year cumulative revision rate for the < 55, 55 to < 65, 65 to < 75 and ≥ 75 groups were 2.1% (CI 0.6–6.1), 1.8% (CI 0.6–5.3), 3.2% (CI 1.5–6.5) and 4.1% (1.7–9.6) with no differences between groups (p = 0.52). Two of the 22 revisions were considered major. The 10 year cumulative reoperation rates were 4.5% (CI 2.0–10.0), 3.0% (CI 1.3–6.5), 3.8% (CI 2.0–7.1) and 4.1% (CI 1.7–9.6) with no differences between groups (p = 0.81). The 10 year median Oxford Knee Scores were 42.5, 46.5, 45 and 42.5, respectively. The 10 year median Objective American Knee Society Scores were 95 for all age groups.

Conclusion
The cementless mobile bearing UKR has low reoperation and revision rates and similar functional outcomes in all age groups. Cementless UKR should be used in all age groups and age should not be considered a contraindication.

Level of evidence
III.
Smoothing destination-specific migration flows
Authors: Dyrting Sigurd , Taylor Andrew 
Published: February 2021

AbstractAccurately estimating age profiles for destination-specific migration is requisite to understanding the determinants of population growth and projecting future change as migration is the primary growth determinant for most regions. In Australia, place-to-place flows based on the age profile of migration derived from census data are commonly used to empirically estimate destination-specific internal migration. However, such flows are heterogeneous and census data is imperfect for accurately generating migration-age profiles. Demographers have addressed this by developing a range of methods for smoothing migration probabilities. These address smoothing on a bi-regional basis, primarily with one destination–origin pairing. We propose a non-parametric method for smoothing destination-specific migration probabilities which can be applied to multi-regional smoothing and is within the generation–distribution framework of Rogers et al. (Environ Plan A 34:341–359, 2002). We demonstrate that, if total age-specific out-migration has already been estimated, smoothing destination-specific migration ratios provides a solution to imperfect input data. Using the example of Australian interstate migration, we show how the method can give an accurate fit to the migration ratio profile across high-curvature ages and a good treatment of sample noise both when the population at risk is low, such as at advanced ages, and when the destination has a low conditional probability of migration. An implementation of the method is available as an Excel add-in.
UHPLC-IM-Q-ToFMS analysis of maradolipids, found exclusively in Caenorhabditis elegans dauer larvae
Authors: Witting Michael , Schmidt Ulrike , Knölker Hans-Joachim 
Published: February 2021

AbstractLipid identification is one of the current bottlenecks in lipidomics and lipid profiling, especially for novel lipid classes, and requires multidimensional data for correct annotation. We used the combination of chromatographic and ion mobility separation together with data-independent acquisition (DIA) of tandem mass spectrometric data for the analysis of lipids in the biomedical model organism Caenorhabditis elegans. C. elegans reacts to harsh environmental conditions by interrupting its normal life cycle and entering an alternative developmental stage called dauer stage. Dauer larvae show distinct changes in metabolism and morphology to survive unfavorable environmental conditions and are able to survive for a long time without feeding. Only at this developmental stage, dauer larvae produce a specific class of glycolipids called maradolipids. We performed an analysis of maradolipids using ultrahigh performance liquid chromatography-ion mobility spectrometry-quadrupole-time of flight-mass spectrometry (UHPLC-IM-Q-ToFMS) using drift tube ion mobility to showcase how the integration of retention times, collisional cross sections, and DIA fragmentation data can be used for lipid identification. The obtained results show that combination of UHPLC and IM separation together with DIA represents a valuable tool for initial lipid identification. Using this analytical tool, a total of 45 marado- and lysomaradolipids have been putatively identified and 10 confirmed by authentic standards directly from C. elegans dauer larvae lipid extracts without the further need for further purification of glycolipids. Furthermore, we putatively identified two isomers of a lysomaradolipid not known so far.
Graphical abstract
Ionic basis of atrioventricular conduction: ion channel expression and sarcolemmal ion currents of the atrioventricular canal of the rainbow trout (Oncorhynchus mykiss) heart
Authors: Hassinen Minna , Dzhumaniiazova Irina , Abramochkin Denis V. , Vornanen Matti 
Published: February 2021

AbstractAtrioventricular (AV) nodal tissue synchronizes activities of atria and ventricles of the vertebrate heart and is also a potential site of cardiac arrhythmia, e.g., under acute heat stress. Since ion channel composition and ion currents of the fish AV canal have not been previously studied, we measured major cation currents and transcript expression of ion channels in rainbow trout (Oncorhynchus mykiss) AV tissue. Both ion current densities and expression of ion channel transcripts indicate that the fish AV canal has a characteristic electrophysiological phenotype that differs from those of sinoatrial tissue, atrium and ventricle. Two types of cardiomyocytes were distinguished electrophysiologically in trout AV nodal tissue: the one (transitional cell) is functionally intermediate between working atrial/ventricular myocytes and the other (AV nodal cell) has a less negative resting membrane potential than atrial and ventricular myocytes and is a more similar to the sinoatrial nodal cells in ion channel composition. The AV nodal cells are characterized by a small or non-existent inward rectifier potassium current (IK1), low density of fast sodium current (INa) and relatively high expression of T-type calcium channels (CACNA3.1). Pacemaker channel (HCN4 and HCN2) transcripts were expressed in the AV nodal tissue butIfcurrent was not found in enzymatically isolated nodal myocytes. The electrophysiological properties of the rainbow trout nodal cells are appropriate for a slow rate of action potential conduction (smallINa) and a moderate propensity for pacemaking activity (absence ofIK1).
Experiences of people affected by cancer during the outbreak of the COVID-19 pandemic: an exploratory qualitative analysis of public online forums
Authors: Colomer-Lahiguera Sara , Ribi Karin , Dunnack Hayley J. , Cooley Mary E. , Hammer Marilyn J. , Miaskowski Christine , Eicher Manuela 
Published: February 2021

Abstract
Purpose
Studies focusing on patients with and survivors of cancer during the COVID-19 pandemic highlight unique psychological and behavioral challenges. These findings were obtained in surveys using self-report questionnaires with pre-specified response options that may not capture the broad range of experiences of individuals affected by cancer, including people with cancer and informal caregivers, in this unprecedented situation. Online forums produce a large amount of valuable first-hand user-generated content that can be used to better understand their day-to-day lives. This study, based on the analysis of narratives in cancer online forums, aims to describe and categorize the experiences of people affected by cancer during the outbreak of the COVID-19 pandemic.

Method
An inductive, descriptive, thematic approach was applied to publicly available cancer forums from Germany, the USA, the UK, and Ireland posted between mid-March and mid-April 2020.

Results
An analysis of the content of 230 main posts revealed three major themes: (1) concerns related to the impact of COVID-19 on cancer care, the risks and fears of getting infected, logistic issues, and economic impact; (2) adaptation challenges faced at the individual and societal level; and (3) the need for advice including information about COVID-19 and the (self-)management of cancer symptoms and treatment.

Conclusion
Our qualitative description of the experiences of people affected by cancer during the COVID-19 pandemic outbreak can help to improve communication, education, and the development of supportive care strategies. Furthermore, the themes and subthemes identified could potentially inform item development for future self-report questionnaires.
Integration of photogrammetry from unmanned aerial vehicles, field measurements and discrete fracture network modeling to understand groundwater flow in remote settings: test and comparison with geochemical markers in an Alpine catchment
Authors: Binda Gilberto , Pozzi Andrea , Spanu Davide , Livio Franz , Trotta Sara , Bitonte Raffaele 
Published: February 2021

AbstractFast and cost-effective techniques for hydrogeological modeling are of broad interest for water resources exploitation, especially in remote settings, where hydrogeological measurements are difficult to perform. Unmanned aerial vehicles (UAV)-based techniques are potentially useful for these aims, but their application is still limited. In this study, a field-based approach and UAV-based approach are integrated for the computation of a discrete fracture network model of a fractured aquifer in the Central Alps. Then, calculated directions of the hydraulic conductivity components were compared with a geostatistical analysis of geochemical markers from sampled spring waters, to infer a conceptual model of groundwater flow. The comparison of field-based and UAV-based fracture measurements confirmed a good matching for fracture orientations and recognized a more reliable estimation of fracture dimensions for the UAV-based dataset. Nonetheless, an important variable for hydrogeological modeling—fracture aperture—is not measurable using UAV, as this requires field measurements. The calculated directions of the main conductivities fit well with the analyzed geochemical markers, indicating the presence of two partially separated fractured aquifers and describing their possible groundwater flow paths. The adopted integrated approach confirms UAV-based measurements as a potential tool for characterization of fracture sets as the input for hydrogeological modeling and for a fast and effective surveying tool, reducing time and cost for other following measurements.
Sex differences in the contribution of different physiological systems to physical function in older adults
Authors: Jones Siana , Schultz Martin G. , Tillin Therese , Park Chloe , Williams Suzanne , Chaturvedi Nishi , Hughes Alun D. 
Published: February 2021

AbstractHaving the physical function to undertake activities of daily living (ADLs) is essential in order to maintain independence. The aim of this study is to investigate factors associated with physical function in older adults and determine if these associations differ in men versus women. In total, 726 participants (57% men; 73±7 years old) from a population-based cohort, the Southall and Brent Revisited (SABRE) study, completed questionnaires permitting a physical function score (PFS) to be calculated. Detailed phenotyping was performed including cardiovascular (echocardiography and macrovascular and microvascular functions), skeletal muscle (grip strength and oxidative capacity) and lung (pulmonary) function measurements. In a sub-group, maximal aerobic capacity was estimated from a sub-maximal exercise test. In women versus men, the association between grip strength and PFS was nearly 3 times stronger, and the association between microvascular dysfunction and PFS was over 5 times stronger (standardized β-coefficient (95% CI) 0.34 (0.22, 0.45) versus 0.11 (0.01,0.22) and −0.27 (−0.37, −0.17) versus −0.05 (−0.14, 0.04), respectively). In men, the association between cardiorespiratory fitness and PFS was 3 times greater than that in women (standardized β-coefficient (95% CI) 0.33 (0.22, 0.45) versus 0.10 (−0.04, 0.25). Cardiovascular, skeletal muscle and pulmonary factors all contribute to self-reported physical function, but the relative pattern of contribution differs by sex. Grip strength and microvascular function are most strongly associated with physical function in women while cardiorespiratory fitness is most strongly associated with physical function in men. This is relevant to the design of effective interventions that target maintenance of physical function in old age.
No Trust is Hybrid: Reply to Faulkner
Authors: Noonan Harold W. 
Published: February 2021

AbstractThere is a well-developed literature on trust. In his important article Faulkner (Analysis, 75(3), 424−429, 2015) distinguishes three-place, two-place and one-place trust predicates. He then argues that our more basic notions of trust are expressed by the one-place and two-place predicates. Three-place trust, contractual trust, is not fundamental. This matters. Having a clear understanding of our concepts of trust is important. The most important assumption of Faulkner’s argument is that the notion of trust expressed by the three-place predicate is not attitudinal; it is a ‘metaphysical hybrid of attitude and action’. I argue that this is wrong. All three notions are attitudinal and no reason exists to deny that the one-place and two-place notions derive from the three-place one. Once one rejects Faulkner’s assumption that the three-place notion can be separated off from the others as a metaphysical hybrid argument for the priority of the one-place and two-place notions collapses.
Insight into the oxidative desulfurization of high-sulfur petroleum coke under mild conditions: a journey of vanadium-substituted Dawson-type phosphotungstic acid
Authors: Li Fu-Min , Hua Ming-Qing , Wei Yan-Chen , Liu Ji-Xing , Gong Jia-Hong , Wang Chao , Wu Pei-Wen , Huang Yan , Li Hua-Ming , Zhu Wen-Shuai 
Published: February 2021

AbstractHigh-sulfur petroleum coke (HSPC), that is a by-product from slag oil in the coking process of refining, shows versatility values in practical applications and, however, concentrates the majority of organic sulfur. Herein, we design and construct a highly effective CTAB@HPA composites to be explored for the catalytic oxidative desulfurization of HSPC under mild conditions using hydrogen peroxide as the oxidant and 1-butyl-3-methylimidazole tetrafluoroborate ionic liquid as the extractant. The results demonstrate that the sulfur content of HSPC could be strikingly reduced from 4.46 wt% to 2.48 wt% under 60 °C and atmospheric pressure, and that the organic sulfur in HSPC is mainly oxidized to sulfoxide, sulfone and sulfate, which latter can be directly separated from petroleum coke. Moreover, the effect of reaction conditions on the desulfurization performance of HSPC as well as the catalytic oxidation reaction kinetic of HSPC desulfurization was systematically investigated. Furthermore, a mechanism for the oxidative desulfurization of HSPC over CTAB@HPA catalysts was proposed. Therefore, this work provides new insight into how to construct active catalysts for the desulfurization of HSPC under mild conditions.
Paclobutrazol Improves Sesame Yield by Increasing Dry Matter Accumulation and Reducing Seed Shattering Under Rainfed Conditions
Authors: Mehmood Muhammad Zeeshan , Qadir Ghulam , Afzal Obaid , Din Atta Mohi Ud , Raza Muhammad Ali , Khan Imran , Hassan Muhammad Jawad , Awan Samrah Afzal , Ahmad Shakeel , Ansar Muhammad , Aslam Muhammad Aqeel , Ahmed Mukhtar 
Published: February 2021

AbstractSeveral biotic and abiotic stresses significantly decrease the biomass accumulation and seed yield of sesame crops under rainfed areas. However, plant growth regulators (such as Paclobutrazol) can improve the total dry matter and seed production of the sesame crop. The effects of the paclobutrazol application on dry matter accumulation and seed yield had not been studied before in sesame under rainfed conditions. Therefore, a two-year field study during 2018 and 2019 was conducted with key objectives to assess the impacts of paclobutrazol on leaf greenness, leaf area, total dry matter production and partitioning, seed shattering, and seed yield of sesame. Two sesame cultivars (TS-5 and TS-3) were treated with four paclobutrazol concentrations (P0 = Control, P1 = 100 mg L−1, P2 = 200 mg L−1, P3 = 300 mg L−1). The experiment was executed in RCBD-factorial design with three replications. Compared with P0, treatment P3 improved the leaf greenness of sesame by 17%, 38%, and 60% at 45, 85, and 125 days after sowing, respectively. However, P3 treatment decreased the leaf area of sesame by 14% and 20% at 45 and 85 days after sowing than P0, respectively. Compared with P0, treatment P3 increased the leaf area by 46% at 125 days after sowing. On average, treatment P3 also improved the total biomass production by 21% and partitioning in roots, stems, leaves, capsules, and seeds by 23%, 19%, 23%, 22%, and 40%, respectively, in the whole growing seasons as compared to P0. Moreover, under P3 treatment, sesame attained the highest seed yield and lowest seed shattering by 27% and 30%, respectively, compared to P0. This study indicated that by applying the paclobutrazol concentration at the rate of 300 mg L−1in sesame, the leaf greenness, leaf areas, biomass accumulation, partitioning, seed yield, and shatter resistance could be improved. Thus, the optimum paclobutrazol level could enhance the dry matter accumulation and seed production capacity of sesame by decreasing shattering losses under rainfed conditions.
Evaluation of machining performance and multi criteria optimization of novel metal-Nimonic 80A using EDM
Authors: Shukla Vikas K. , Kumar Rakesh , Singh Bipin Kumar 
Published: February 2021

AbstractThis study focused to machine novel Nimonic 80A through Electric Discharge Machine process. The process parameters are optimised to achieve high surface integrity along with high material removal rate (MRR) with minimum energy consumption. Central composite design along with analysis of variance technique has been applied to make correlation between the process parameter and responses. The developed model of surface roughness shows that the peak current and pulse-on time have significant effect whereas; a little effect of pulse-off time. The said result may be obtained due to simultaneous action of deposition and notching (removal) of material in order to form crater. In case of MRR, the pulse-on time and peak current are found as significant factors with increasing trend (i.e. when the input values are increased the MRR increases) whereas; a reverse trend is noticed with pulse-off time. The optimum values for maximum MRR (0.512444 gm/min) and minimum surface roughness (7.82203 µm) with 81% desirability are obtained for the process parameter as 13.49 A peak current, 150 µs pulse-on time and 4 µs pulse-off time.