bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arteriotomy for Carotid Endarterectomy, from Common to Interna or Externa?
Authors: Talay Süreyya 
Published: January 2021

Objectives: In this study, we described and compared a modified carotid endarterectomy surgical technique. Our comparison was between arteriotomy incision from common to interna and from common to externa.
Methods: This study included 73 isolated carotid anrterctomy operations from two different centers. We performed external incision in 61 cases (Group A) and internal incision in 12 cases (Group B). We also elaborated perioperative data and surgical results between Groups. All cases were performed under general anaesthesia.
Results: 2 patients in Group A and 2 patients in Group B died at the early postoperative period due to severe neurological deteriorations in 3 and myocardial infarction in 1 case. All cases were solely operated for carotid artery stenosis. None of these patients were presenting contrlaterally serious carotid artery lesions. 4 patients from Group A and 3 patients from Group B were receiving haemodialysis, perioperatively. Trancient minor neurological complications such as lingual deviation and/or facial asymmetry which were associated with N.Hypoglossus injuries, was observed in 8 cases and 2 cases in Group A and Group B, respectively. Patchplasty was necessary in 5 from Group A. No patchplasty was applied in Group B. We tried to avoid carotid shunt from common to interna in all standart procedures. However, carotid shunt was mandatory in 4 patients and in 1 patient from Group A and B.
Conclusion: Our modified carotid incision from common to externa is almost always suitable for internal plaque removal. Thus, an incision to interna can be avoided which prevents internal artery narrowing, endothelial disruption and/or occlusion prone deterioration and internal artery intraoperative dissection risks. Therefore, we believe that an incision from common to external carotid artery is the first choice surgical approach for carotid endarterectomy.
The characteristics and outcomes of patients with malignant pheochromocytoma and paraganglioma: Single-Center Experience
Authors: Gökçay Canpolat Asena , Çorapçıoğlu Demet 
Published: January 2021

ABSTRACT
Introduction: Metastatic pheochromocytomas (PCCs) and paragangliomas (PGLs) (PPGLs) are defined by the presence of metastatic disease in nonchromaffin tissue. It is rare, and there is no guidance for clinical, histological, or biochemical predictors of metastatic behavior. So, we aimed to evaluate our PPGL patients and investigate the features and treatment outcomes of our cohort.
Methods: Between 2010 and 2019, 35 PCC and 3 PGL were included in the study. The age, clinical features, demographic, biochemical, radiological data, and treatment outcomes of the patients were analyzed.
Results: The mean age was 38.3 ± 15.3 years, and the female to male ratio was 22/16. Twenty-one patients had hereditary causes of PCC (Multiple endocrine neoplasia (MEN) type 2A n:17; MEN2B n:4 and Neurofibromatosis n:1). The metastatic disease was seen in four of PCCs and one of PGLs. The metastatic cases were sporadic both in PCC and PGL patients. The mean greatest dimension of the primary tumor of metastatic PPGL cases was 4.5±3.2 cm. The sites for metastasis for PCC were liver, bones, lungs, and lymph nodes in all cases. Surgery was performed, cytotoxic chemotherapy, and 131I-MIBG radionuclide therapy were given for all PCCs and external beam radiation for PGL. Three of the cases were stable with cytotoxic chemotherapy and 131I-MIBG, but one case declined, and after a total of four cycles of 177Lu therapy, she died.
Conclusion:: In our tertiary referral center, the majority of the patients who were followed with PGGLs have hereditary/genetic etiology. It is observed that malignant PPGLs constitute 10.5 % of our patients, the same as the literature. Patients should be directed to centers where chemotherapy and theranostic treatments with a multidisciplinary approach are present in cases of metastatic disease in an individualized manner.

Keywords: Pheochromocytoma, paraganglioma, metastatic disease, theranostic treatment
HUBUNGAN ANTARA PERSEPSI SISWA TENTANG PEMANFAATAN LKS DAN KEMANDIRIAN BELAJAR DENGAN HASIL BELAJAR BAHASA INGGRIS
Authors: Pratama Galih , Falah Saiful 
Published: January 2021

Penelitian ini bertujuan untuk menguji Hubungan antara Persepsi Siswa tentang Pemanfaatan LKS dan Kemandirian Belajar dengan Hasil Belajar Bahasa Inggris siswa kelas IX di SMP Negeri 3 Cibinong Kabupaten Bogor. Sampel yang diambil berjumlah 40 responden dengan teknik random sampling. Penelitian dibatasi tiga variabel yang akan diteliti: sebagai variabel bebas penelitian yaitu Persepsi Siswa tentang Pemanfaatan LKS (X1), Kemandirian Belajar (X2), dan variabel terikat yaitu Hasil Belajar Bahasa Inggris (Y). Metode penelitian yang digunakan adalah korelasional. Analisis yang digunakan terhadap data penelitian adalah analisis korelasi regresi sederhana dan analisis korelasi regresi berganda. Analisis korelasi regresi sederhana digunakan untuk mengetahui besar Hubungan antara Persepsi Siswa tentang Pemanfaatan LKS dan Kemandirian Belajar dengan Hasil Belajar Bahasa Inggris secara sendiri-sendiri sedangkan analisis korelasi regresi berganda untuk mengetahui Hubungan antara Persepsi Siswa tentang Pemanfaatan LKS dan Kemandirian Belajar secara bersama-sama. Data hasil penelitian mengindikasikan bahwa: (1) Persepsi Siswa tentang Pemanfaatan LKS memiliki hubungan dengan Hasil Belajar Bahasa Inggris dengan r= 0,5827, R= 33,96%. Persepsi Siswa tentang Pemanfaatan LKS terhadap Hasil Belajar Bahasa Inggris sebesar 33,96%. (2) Kemandirian Belajar memiliki hubungan dengan Hasil Belajar Bahasa Inggris dengan r=0,499, R= 24,9%. Kemandirian Belajar memiliki hubungan dengan Hasil Belajar Bahasa Inggris sebesar 24,9%. (3) Sedangkan Persepsi Siswa tentang Pemanfaatan LKS dan Kemandirian Belajar memiliki hubungan secara bersama-sama dengan Hasil Belajar Bahasa Inggris dengan r= 0,585, R 34,2%. Sumbangan pengaruh Persepsi Siswa tentang Pemanfaatan LKS dan Kemandirian Belajar memiliki hubungan secara bersama-sama terhadap Hasil Belajar Bahasa Inggris sebesar 34,2%. Maka dapat disimpulkan bahwa dengan optimalisasi pemanfaatan LKS dan Kemandirian Belajar yang baik akan meningkatkan Hasil Belajar Bahasa Inggris siswa
Activated Carbon from Sugarcane (Saccharum officinarum L.) Bagasse for Removal Ca2+ and Mg2+ Ion from Well Water
Authors: Kurniasari Ira Tyas , Riyanto Cucun Alep , Martono Yohanes 
Published: January 2021

Humans need water with good quality to fulfill their needs. Water with high hardness content will have a bad impact if consumed continuously, so the adsorption method is carried out to reduce the concentration of Ca2+ and Mg2+ ions. The adsorption process uses sugarcane bagasse activated carbon (SBAC) and the tested water sample is well water in District Jati, Kudus. Synthesis of SBAC was conducted with H3PO4 30% as an activator at an impregnation ratio of 1:5 (w/w) at temperature 700°C. The FTIR result showed that SBAC contains O-H, C-H, C=C, C≡C, and C-O as functional groups. Analysis result with the XRD instrument showed that the microstructure of SBAC that is formed is turbostatic structure and amorphous. Modeling isotherm suitable for SBAC adsorption on Ca2+ ions is Langmuir isotherm where the R2 value is 0.9134 which shows that the adsorption process occurs chemically and monolayer. Modeling isotherm suitable for SBAC adsorption on Mg2+ ions is Elovich isotherm where the R2 value is 0.8638 which means that the adsorption process is multilayer and adsorption in non-ideal conditions. Modeling kinetics suitable for SBAC adsorption on Ca2+ and Mg2+ ions is Pseudo Orde 2 where the R2 value is 0.9395 and 0.7274. Percent efficiency value of sugarcane activated carbon adsorption of Ca2+ dan Mg2+ ions on District Jati, Kudus well water is 14.44% and 8.94% and 40 minutes stirring time.
Antibacterial Activity of Flavonoid-Rich Fractions Of Citrus Maxima Peel Extract
Authors: Br Karo Reh Malem , Manalu Putranto , Sinurat Jhon Patar 
Published: January 2021

Natural products can be used as an alternative in the treatment of various diseases such as infectious diseases due to the bioactive compounds contained therein. Moreover nowdays, there are many antibiotic resistance in the treatment of infectious diseases. Citrus maxima is one of the natural products. Citrus maxima have been used for many diseases in traditional medicine.The aim of this study was to investigate the antibacterial activity of flavonoid-rich fractions of citrus maxima peel extract. The bioactive compounds contained in Citrus maxima peel were extracted by maceration method using 96% ethanol solvent. Fractionation was conducted using liquid-liquid extraction using a solvent of water and ethyl acetate obtained ethyl acetate fraction. In this fraction, the TLC test was carried out to confirm the presence of phenolic and flavonoid compounds. The antibacterial activity testing for ethyl acetate fraction against S.aureus and E.coli was determined by disk diffusion method with concentration of 25 ppm, 50 ppm, 75 ppm and 100 ppm. The ciprofloxacin and distilled water were used as positive and negative control, respectively. The result of this study showed that ethyl acetate fraction ( flavonoid-rich fractions) Of Citrus Maxima has potential as antibacterial for bacterial S.aureus and E.coli with medium inhibitory ability in all of concentration ranges. The highest inhibition zone for S.aureus was found at a concentration of 100 ppm while for E.coli was at a concentration of 75 ppm.
OK, Zoomer - a digitális tanulás problémái
Authors: Nagy Ádám , Fekete Mariann 
Published: January 2021

A cikk értelmezni igyekszik a pandémiás helyzet okozta karantén oktatási környezetét. Egyfelől bemutatja annak jellemzőit, különösképpen visszásságait, amikor digitális bevándorlók kerülnek a digitális bennszülöttek „vadászterületére”. Másfelől igyekszik számba venni a digitális oktatás hátulütőit. The article seeks to interpret the educational environment of quarantine caused by a pandemic situation. On the one hand, it presents the characteristics, especially the anomalies of digital immigrants entering the “hunting ground” of digital natives. On the other hand, it seeks the setbacks of digital education.
Szervezeti modell fejlesztése a közszolgáltatásban
Authors: Vörös Péter 
Published: January 2021

A közszolgáltatásban napjainkban is a XX. század szervezeti modellje a domináns.A változást a XXI. század kihívásai motiválják, sürgetését a fejlődés dinamikája, a verseny kiéleződése, az ökokörnyezet katasztrofális romlása indukálja. A szervezet felépítése nemcsak a működés hatékonyságát határozza meg, de az ott dolgozók motiváltságát, gondolkozását és így teljesítményét is. A közszolgáltatási szervezetek átalakítása egy innovációs szervezeti modell irányába hozzájárulhat a lakossági igények magasabb színvonalon történő kielégítéséhez, a gazdasági környezet dinamizálásához, a humánerőforrás teljesítményének növeléséhez, a környezetvédelem és -fejlesztés magasabb szint emeléséhez.A tanulmány az innovatív szervezet működésének elméleti bemutatása mellett a gyakorlat terepén is bemutatja az átalakítás folyamatát, lehetőségeit, irányát és lehetséges eredményét. In public services, the 20th century organizational model is dominant in our days.Changes are motivated by 21st century challenges and are urged by the dynamics of development, the sharpening of competition and the catastrophic devastation of the ecological environment. Transforming the public service organizations according to an innovation organizational model may contribute to the fulfilment of public demands at a higher standard, to a more dynamic economic environment, the improvement of human resource performance and to raising environmental protection and development to an improved level.Besides introducing the theory of the operation of an innovative organization, the study presents the process, the possibilities, the trends and the possible results of this transformation in the field of practice, as well.
A pedagógus kiégés jelenségének vizsgálata
Authors: Kricsfalussy Anna 
Published: January 2021

Napjainkban számos változás érintette, érinti a szakképzés egészét, ami kihatással van a rendszerben dolgozó pedagógusokra is. Kutatásomban érdekelt, hogy a személyiségvonások (pl. empátia, kötelességtudat, nyitottság, elhivatottság), amelyek a pedagógusi pályára alkalmas (abb) á tesznek valakit, mennyiben játszanak szerepet a kiégési szintjét tekintve. Kérdőívcsomagomat 300, a szakképzésben dolgozó pedagógus munkatársam töltötte ki, mind a 44 szakképzési centrum érintve lett.Tanulmányomban bemutatom a kiégés (burnout) szindrómát, ezen belül a pedagógus kiégés jelenségét, majd pedig a vizsgálataimat és eredményeimet összegzem. Kutatásom hipotéziseinek eredményeit és a statisztikai mutatóit összevetem a korábbi eredményekkel, majd pedig a pedagógus burnout prevenciójának lehetőségeit, és a lehetséges megoldási utakat veszem számba.Munkámban kiemelem azokat a pontokat ahonnan még visszafordítható a kiégés folyamata, és bemutatok a preventív stresszmenedzsment modelljén keresztül több intervenciós módszert. Nowadays, many changes have affected, act on the whole of vocational training, which also impact the teachers working in the system. In my research, I am interested in the extent to which personality traits (eg empathy, duty, openness, dedication) that make a person fit into the teaching profession play a role in their burnout. My questionnaire package was completed by 300 of my vocational training teacher staff and all 44 centers of vocational training were affected.In my study, I present burnout syndrome, including the phenomenon of teacher burnout, and then summarize my research and results. I compare the results of my research hypotheses and statistical indicators with previous results, then consider the possibilities of teacher burnout prevention and possible solutions.In my work, I highlight the points from which the burnout process can be reversed and introduce several intervention methods through the preventive stress management model.
Property as an Object of Theoretical Research: Political Economy and Economic Policy
Authors: Buzgalin Alexandr V. 
Published: January 2021

The article reveals the understanding of property in institutionalism and in classical political economy with an emphasis on the Marxist direction of the latter. It is shown that in the works of modern authors belonging to the Post-Soviet School of Critical Marxism – one of the main directions of modern theory of classical political economy in Russia – the specific, concrete historical content of property relations is firstly investigated. This content in the framework of this direction, inheriting the tradition of the “Tsagolovskaya” school of political economy, is connected through the system of production relations of a particular society. It is shown that both private and public forms of property have different socio-economic contents in historically different socio-economic systems – pre-bourgeois, bourgeois, post-capitalist. The author proposes political and economic systematization of patterns of property that are characteristic of the modern stage of economic development, which in the article is defined as late capitalism. These forms include not only different types of private and public property, but also transitional forms that contradictory combine private-capitalist and associated forms of appropriation. It is specially emphasized that public property is not reducible to state property and includes a special type of relationship – “ownership by everybody of everything”, which is characteristic of the sphere of co-creation. It is shown that in certain types of economy, state ownership can hide relations not only of public, but also of private-capitalist appropriation, as well as non-economic coercion. The contradictions of the transformation of property relations under the conditions of late capitalism and the most relevant practical problems associated with this are revealed.The article includes a polemic dialogue of the author with representatives of the institutional direction and the works of George B. Kleiner.
PENGARUH HIPNOTERAPI TERHADAP PENURUNAN SKALA NYERI DISMENORE.
Authors: Mizam Ari Kurniyanti 
Published: January 2021

Dysmenorrhea is pain during menstruation. Symptoms of dysmenorrhea are very typical, namely complaints of abdominal pain or stomach cramps. The management of primary dysmenorrhea pain can be done by non pharmacological. One of the non-pharmacological relaxation techniques is hypnotherapy because hypnotherapy techniques can produce a sense of comfort and can produce endorphin hormones that can suppress pain. Aim : Knowing the effect of hypnotherapy on reducing the primary dysmenorrhea pain scale based on literature studies in the last 6 years.Method :The method used in this literature study is to obtain articles from the search results of scientific research articles from the 2014-2020 period using the Taylor & Francis Group, Sienta, DOAJ, Research Gate, and Google Shcolar data base. As many as 120 articles were obtained which were then carried out by the identification and screening process, so that 10 articles were obtained that match the inclusion criteria, with a pre-experimental research design of 5 articles and a quasi-experimental study of 5 articles. Result: The test results of these journals which state that the p value <0.05 is defined as a significant difference between before the intervention was given and after the intervention was given.Conclusion: The conclusion from this literature review is that there is an effect of hypnotherapy on reducing the pain scale of primary dysmenorrhea. Suggestions for nursing students and nurses, to improve the science of hypnotherapy as part of complementary therapy to overcome dysmenorrhea pain problems.
Bibliography : 36 literature (2010-2020)
Keywords : hypnotherapy, primary, dysmenorrhea
Activation of the Complement System in the Lower Genital Tract During Pregnancy and Delivery
Authors: Livson Sivan , Jarva Hanna , Kalliala Ilkka , Lokki A. Inkeri , Heikkinen-Eloranta Jenni , Nieminen Pekka , Meri Seppo 
Published: January 2021

BackgroundHuman pregnancy alters profoundly the immune system. The local involvement and mechanisms of activation of the complement system in the cervicovaginal milieu during pregnancy and delivery remain unexplored.ObjectivesTo determine whether normal pregnancy and delivery are associated with local activation of complement or changes in the immunoglobulin profile in the cervix.Study DesignThis study was designed to assess IgA, IgG, and complement activation in the cervicovaginal area in three groups of patients: i) 49 pregnant women (week 41+3–42+0) not in active labor, ii) 24 women in active labor (38+4–42+2), and iii) a control group of nonpregnant women (n=23) at child-bearing age. We collected mucosal samples from the lateral fornix of the vagina and external cervix during routine visits and delivery. The Western blot technique was used to detect complement C3 and its activation products. For semiquantitative analysis, the bands of the electrophoresed proteins in gels were digitized on a flatbed photo scanner and analyzed. IgA and IgG were analyzed by Western blotting and quantified by ELISA. One-way ANOVA and Tukey’s Multiple Comparison tests were used for statistical comparisons.ResultsA higher abundance but lower activation level of C3 in both the external cervix (P&lt;0.001) and lateral fornix of the vagina (P&lt;0.001) was observed during delivery (58 ± 22, n= 24) in comparison to the groups of nonpregnant (72 ± 13%; mean ± SD, n=23) and pregnant women (78 ± 22%, n=49). Complement activating IgG was detected in higher abundance than IgA in the cervicovaginal secretions of pregnant women. In a small proportion samples also C3-IgG complexes were detected.ConclusionsOur results reveal an unexpectedly strong activation of the complement system and the presence IgG immunoglobulins in the cervicovaginal area during pregnancy, active labor, and among nonpregnant women. In contrast to the higher amounts of C3 in the cervicovaginal secretions during labor, its activation level was lower. Complement activating IgG was detected in higher concentrations than IgA in the mucosal secretions during pregnancy and labor. Taken together our results imply the presence a locally operating humoral immune system in the cervicovaginal mucosa.
Endosphere Microbiome and Metabolic Differences Between the Spots and Green Parts of Tricyrtis macropoda Leaves
Authors: Wang Yan , Cheng Huyin , Chang Fan , Zhao Le , Wang Bin , Wan Yi , Yue Ming 
Published: January 2021

BackgroundPlant leaves are important organs for photosynthesis and biological energy production. The leaves of Tricyrtis macropoda have an unusual spotted pattern. However, whether the spots of T. macropoda affect the plant microbiome and metabolites is unclear. In this study, we compared differences in the endosphere microbiome and plant metabolites in green parts and spots and the effects of spots on the photosynthesis of leaves.Methods16S/ITS sequences and metabolite spectra were obtained by high-throughput amplicon sequencing and ultra-high-performance liquid chromatography–high-resolution mass spectrometry, respectively. Changes in the diversity of the endophytic microbial community and metabolites were studied, and the effect of T. macropoda leaf spots on photosynthesis was examined by chlorophyll fluorescence.ResultsThe results showed that the relative abundance of Cercospora fungi in the leaf spots of T. macropoda was significantly higher than that in the green parts (P &lt; 0.05) while Colletotrichum fungi showed low abundance in the spots. Alkaloid and ketone metabolites were decreased in the green parts compared with the spots, and amino acids, organic acids, lipids, and other compounds were increased in the green parts compared with the spots. A combined analysis of microbial communities and metabolites showed a significant correlation between the endophytic fungal communities and metabolite production. The changes in these metabolites may cause changes in local leaf color. In addition, we found that the spot areas of T. macropoda can be photosynthetically normal.ConclusionThis research showed the relationship between endophytic microorganisms and metabolites, and the findings advance our understanding of endophyte–plant interactions and provide a new direction for investigating the relationship between endophytes and phenotypes.