bluuebunny/crossref_metadata_2025_split huggingface dataset:
Elucidating the immune infiltration in acne and its comparison with rosacea by integrated bioinformatics analysis
Authors: Yang Lu , Shou Yan-Hong , Yang Yong-Sheng , Xu Jin-Hua 
Published: March 2021

Background
Acne vulgaris and rosacea are common inflammatory complications of the skin, both characterized by abnormal infiltration of immune cells. The two diseases can be differentiated based on characteristic profile of the immune cell infiltrates at the periphery of disease lesions. In addition, dysregulated infiltration of immune cells not only occur in the acne lesions but also in non-lesional areas of patients with the disease, thus characterizing the immune infiltration in these sites can further enhance our understanding on the pathogenesis of acne.

Methods
Five microarray data-sets (GSE108110, GSE53795, GSE65914, GSE14905 and GSE78097) were downloaded from Gene Expression Omnibus. After removing the batch effects and normalizing the data, we applied the CIBERSORT algorithm combined with signature matrix LM22, to describe 22 types of immune cells’ infiltration in acne less than 48 hour (H) old, in comparation with non-lesional skin of acne patients, healthy skin and rosacea (including erythematotelangiectatic rosacea, papulopustular rosacea and phymatous rosacea) and we compared gene expression of Th1 and Th17-related molecules in acne, rosacea and healthy control.

Results
Compared with the non-lesional skin of acne patients, healthy individuals and rosacea patients, there is a significant increase in infiltration of neutrophils, monocytes and activated mast cells around the acne lesions, less than 48 H after their development. Contrarily, few naive CD4+ T cells, plasma cells, memory B cells and resting mast cells infiltrate acne sites compared to the aforementioned groups of individuals. Moreover, the infiltration of Regulatory T cells (Tregs) in acne lesions is substantially lower, relative to non-lesional sites of acne patients and skin of healthy individuals. In addition, non-lesional sites of acne patients exhibit lower infiltration of activated memory CD4+ T cells, plasma cells, memory B cells, M0 macrophages, neutrophils, resting mast cells but higher infiltration of Tregs and resting dendritic cells relative to skin of healthy individuals. Intriguingly, we found that among the 3 rosacea subtypes, the immune infiltration profile of papulopustular rosacea is the closest to that of acne lesions. In addition, through gene expression analysis of acne, rosacea and skin tissues of healthy individuals, we found a higher infiltration of Th1 and Th17 cells in acne lesions, relative to non-lesional skin areas of acne patients.

Conclusions
Our study provides new insights into the inflammatory pathogenesis of acne, and the difference between acne and rosacea, which helps in differentiating the two diseases. Our findings also guide on appropriate target therapy of the immune cell infiltrates in the two disease conditions.
Virtual Laboratory to Support a Practical Learning of Micro Power Generation in Indonesian Vocational High Schools
Authors: Bima Marshal , Saputro Herman , Efendy Agus 
Published: March 2021

Abstract
The rapid changes in industrial revolution 4.0 demand change in education, especially at vocational education. Teachers in Vocational High School (VHS) in Indonesia are expected to bring technology-based innovations to achieve success in learning. Learning facilities are one of the factors supporting the success of learning class. Ideally, Indonesian Vocational High Schools have facilities and infrastructure following industrial. Currently, schools have difficulty providing learning support facilities and infrastructure following those in the industry. Thus, the equipment in the school laboratory is irrelevant to the existing equipment in the industry. The practicum apparatus gap between VHS and industry requires appropriate and effective solutions. The gap occurred in practical learning of micro power generation Indonesian VHS. On the other hand, virtual laboratories in the learning process can help students learn an object that cannot be presented in the classroom. By using virtual laboratories, students learn to use industry apparatus through virtual forms. This research aims to overcome the problem of practical learning in VHS, especially on practical learning of micro power generation through the virtual laboratory. This study used the 4D model approach (Define, Design, Develop, and Disseminate). The result showed that the virtual laboratory of micropower generation effectively supported learning and transfer of knowledge in practical learning, especially during the covid 19 pandemics.
Efficiency of electric vehicle interior heating systems at low ambient temperatures
Authors: Gis Maciej , Wiśniowski Piotr , Bednarski Mateusz 
Published: March 2021

Abstract
The electric car market is becoming more and more extensive. According to ACEA, in 2019, 549,387 full electric passenger vehicles, hybrid plug-ins and hydrogen vehicles were registered in the European Union. Thus, it is an increase of 52.9 percent compared to 2018. Germany is the leader with 108 839 registrations of vehicles (+60.9% y/y). Great Britain achieved an increase of 21.5 percent y/y and the number of registrations at 72 834 pieces. The Netherlands came next (66 957 pcs, + 146.3% y/y), France (61 356 pcs, +34.6% y/y) and Sweden (40 406 pcs, + 39.4% y/y).
Registration results in Europe shows that the popularity of electric vehicles is increasing. Along with the development of this type of vehicles, the technology used in their construction also changes. The biggest calls at the moment are batteries for these vehicles, as well as their ranges on a single charge. There are already vehicles with ranges of 500 km or even 600 km.
However, it turns out that these are not the only problems with electric vehicles One of the drawbacks is the way they heat their passenger cabins. There is no typical heater in an electric vehicle as in the case of a vehicle with a conventional drive. For this purpose, e.g. an electric heater with a blower is used for this purpose. For this reason, the authors of the paper decided to determine the efficiency of the heating system in an electric vehicle at low ambient temperatures.
Own tests were carried out on the vehicle at temperatures of +5°C, −5°C and −10°C. Based on the research, the authors of the paper could draw conclusions on how to heat the interior in the electric vehicle under test, as well as check whether the efficiency of such a system for individual places in the car is sufficient to obtain the set temperature.
Prediction of the parameters and the hot open die elongation forging process on an 80 MN hydraulic press
Authors: Dindorf Ryszard , Takosoglu Jakub , Wos Piotr 
Published: March 2021

Abstract
The main task of the study was to develop and implement predictive control in the hot open die forging process of heavy, large, and hard deformable steel forgings on an 80 MN hydraulic press at the Forged Products Department (FPD) of Celsa Huta Ostrowiec (CHO). The predicted hot flow stresses and the predicted deformation/forging forces as a function of the parameters of the elongation forging process were determined. The predicted parameters of the forging process were included in the dynamic model of the hydraulic forging press. Generalized predictive control (GPC) algorithm of the hot open-die forging process on the hydraulic press was developed. The use of predictive control solved the uncertainty of the hot open forging process, which depends on the dimensions, shapes, and material properties of the forgings, as well as the parameters of the hydraulic press and forging tools.
Generic cuspidal representations of 𝑈(2, 1)
Authors: Nadimpalli Santosh 
Published: March 2021

Abstract
Let 𝐹 be a non-Archimedean local field, and let 𝜎 be a non-trivial Galois involution with fixed field

F
0

F_{0}

.
When the residue characteristic of

F
0

F_{0}

is odd, using the construction of cuspidal representations of classical groups by Stevens, we classify generic cuspidal representations of

U
⁢

(
2
,
1
)

⁢

(

F
/

F
0

)

U(2,1)(F/F_{0})

.
A class of non-weight modules of 𝑈𝑝(𝖘𝖑2) and Clebsch–Gordan type formulas
Authors: Cai Yan-an , Chen Hongjia , Guo Xiangqian , Ma Yao , Zhu Mianmian 
Published: March 2021

Abstract
In this paper, we construct a class of new modules for the quantum group

U
q

⁢

(

s
⁢

l
2

)

U_{q}(\mathfrak{sl}_{2})

which are free of rank 1 when restricted to

C
⁢

[

K

±
1

]

\mathbb{C}[K^{\pm 1}]

.
The irreducibility of these modules and submodule structure for reducible ones are determined.
It is proved that any

C
⁢

[

K

±
1

]

\mathbb{C}[K^{\pm 1}]

-free

U
q

⁢

(

s
⁢

l
2

)

U_{q}(\mathfrak{sl}_{2})

-module of rank 1 is isomorphic to one of the modules we constructed, and their isomorphism classes are obtained.
We also investigate the tensor products of the

C
⁢

[

K

±
1

]

\mathbb{C}[K^{\pm 1}]

-free modules with finite-dimensional simple modules over

U
q

⁢

(

s
⁢

l
2

)

U_{q}(\mathfrak{sl}_{2})

, and for the generic cases, we obtain direct sum decomposition formulas for them, which are similar to the well-known Clebsch–Gordan formula for tensor products between finite-dimensional weight modules over

U
q

⁢

(

s
⁢

l
2

)

U_{q}(\mathfrak{sl}_{2})

.
A composite power quality index for low-voltage active distribution networks
Authors: Thirumala Karthik , Budhavarapu Jayaprakash , Devara Hari Babu 
Published: March 2021

AbstractIn active distribution networks, it is a challenging task for the utility and system operators to identify and analyze the power quality (PQ) disturbance and its cause. Likewise, the consumers are curious about the quality of power supply being provided and the economic impacts of low PQ. Thus, continuous monitoring of the overall quality of the power at the consumer end has become a significant concern in distribution networks. This paper presents a new composite power quality index (CPQI) for low-voltage distribution networks. The CPQI is formulated as a weighted average of five basic parameters, namely voltage level, current harmonic quality, voltage harmonic quality, power factor, and system frequency. The main emphasis is on quantifying the overall quality of the power supply under different PQ disturbance conditions. The CPQI estimate helps in a preliminary investigation of tracking the low PQ location and its source. The proposed CPQI is evaluated on a variety of simulated signals obtained from a CIGRE low-voltage microgrid network. Furthermore, the formulated CPQI is investigated on a LabVIEW-based virtual instrumentation platform with LED loads. It is interpreted from the results that the proposed CPQI is able to evaluate the overall PQ at a load terminal with diverse load conditions subjected to different power quality disturbances.
The elastic-plastic properties of an anti-icing coating on an aluminum alloy: Experimental and numerical approach
Authors: Zhang Wei , Lv Sheng-Li , Gao Xiaosheng , Srivatsan Tirumalai S. 
Published: March 2021

Abstract
In this paper, an attempt is made to describe the method that combines the results obtained from nanoindentation experiment with finite element simulation to determine or establish the elastic-plastic properties of a super-hydrophobic anti-icing coating. The nanoindentation test was conducted and elastic properties of the coating, to include elastic modulus and hardness were obtained. The plastic properties, to include yield stress, monotonic strength coefficient and monotonic strain hardening exponent, were obtained using an inverse, iterative method of experimental measurement in synergism with finite element simulation. This approach, which is a combination of experimental data obtained from the nanoindentation test and results obtained from numerical finite element simulation, was found to be effective for determining mechanical properties of the chosen coating.
Mental health and biological evolution: implications for psychiatry and psychosomatic medicine
Authors: Brüne Martin 
Published: March 2021

Abstract
Psychiatric disorders are common and seem to increase in prevalence worldwide. Most scientific approaches for this phenomenon fail to explain why the majority of mental disorders, unlike most somatic diseases, manifest in early adulthood, why individuals are not more resilient, and why some genes increasing the risk for mental disorders have not been selected against. In this article, an evolutionary perspective on mental health and disorder is taken. This perspective suggests that mismatches between ancestral and contemporary environments contribute to the risk for mental disorders. In addition, predictions from attachment theory and life history theory can explain individual differences with regard to the risk of developing a psychiatric or psychosomatic disorder. Insights from evolutionary approaches to psychiatric and psychosomatic disorders may contribute to improve the prevention and treatment of mental disorders.
Systematic review and meta-analysis of veterinary-related occupational exposures to hazards
Authors: Adebowale Oluwawemimo , Fasanmi Olubunmi Gabriel , Awosile Babafela , Afolabi Monsurat , Fasina Folorunso Oludayo 
Published: March 2021

Abstract
Understanding hazards within the veterinary profession is critical for developing strategies to ensure the health and safety of personnel in the work environment. This study was conducted to systematically review and synthesize data on reported risks within veterinary workplaces. A systematic review of published data on occupational hazards and associated risk factors were searched within three database platforms namely PubMed, Ebscohost, and Google scholar. To determine the proportion estimates of hazards and pooled odds ratio, two random-effects meta-analysis were performed. For the biological, chemical and physical hazards, the pooled proportion estimates were 17% (95% CI: 15.0-19.0, p < 0.001), 7.0% (95% CI: 6.0-9.0%, p < 0.001) and 65.0% (95% CI: 39.0-91.0%, p < 0.001) respectively. A pooled odds ratio indicated the risk of exposures to physical (OR=1.012, 95% CI: 1.008-1.017, p < 0.001) and biological hazards (OR=2.07, 95% CI: 1.70-2.52, p <0.001) increased when working or in contact with animals. The review has provided a better understanding of occupational health and safety status of veterinarians and gaps within the developing countries. This evidence calls for policy formulation and implementation to reduce the risks of exposures to all forms of occupational-related hazards in veterinary workplaces.
Schrödinger’s tridiagonal matrix
Authors: Kovačec Alexander 
Published: March 2021

Abstract
In the third part of his famous 1926 paper ‘Quantisierung als Eigenwertproblem’, Schrödinger came across a certain parametrized family of tridiagonal matrices whose eigenvalues he conjectured. A 1991 paper wrongly suggested that his conjecture is a direct consequence of an 1854 result put forth by Sylvester. Here we recount some of the arguments that led Schrödinger to consider this particular matrix and what might have led to the wrong suggestion. We then give a self-contained elementary (though computational) proof which would have been accessible to Schrödinger. It needs only partial fraction decomposition. We conclude this paper by giving an outline of the connection established in recent decades between orthogonal polynomial systems of the Hahn class and certain tridiagonal matrices with fractional entries. It also allows to prove Schrödinger’s conjecture.
O NON CUMPRIMENTO DA LEI DE GIBRAT EN ECONOMÍAS EN DESENVOLVEMENTO: O CASO DE ECUADOR NO PERÍODO 2000-2013
Authors: SIMBAÑA-TAIPE Luis Enrique , RODRÍGUEZ-GULÍAS María Jesús , RODEIRO-PAZOS David 
Published: March 2021

Ecuador foi un dos países latinoamericanos que experimentou cambiossignificativos no campo social e económico nas últimas décadas, converténdose nunha daseconomías máis importantes da rexión. Por iso, resulta relevante coñecer as relaciónsexistentes entre o tamaño e a taxa de crecemento das empresas deste país. Este traballorealiza a súa achega ao contrastar a lei de Gibrat cunha mostra de 25.179 empresas detodos os sectores económicos para o período 2000-2013. Aplicamos o métodoxeneralizado dos momentos en dous modelos de crecemento e utilízase como medida decrecemento as vendas e o emprego. As descubertas obtidas indican que as taxas decrecemento das empresas grandes son menores cás das pequenas. Ademais, a idade tenunha relación non linear, xa que namentres que nos seus primeiros anos de vida a relacióné negativa, a determinada idade cambia a positiva. Esta investigación achega evidenciaspara a orientación da política pública en países que se atopan en desenvolvemento. Abstract: Ecuador is of the Latin American countries experiencing significant changes inthe social and economic field in recent decades, becoming one of the most importanteconomies in the region. Therefore, it is relevant to know the existing relationshipsbetween the size and growth of companies in this country. This study accomplishes this bycontrasting Gibrat's law in a sample of 25,179 companies from all economic sectors for theperiod 2000-2013. We apply the generalized method of moments in two growth modelsand it is used as a measure of growth regarding both sales and employment. Findingsshow that the growth rates of large companies are lower than those of small companies. Inaddition, age has a non-linear relationship, while in the first years of life the relationship isnegative, at a certain age changes to positive. This research provides evidence for theorientation of public policies in developing countries.
Excess weight in children living in rural areas related to the nutritional profile and to maternal habits
Authors: Lagares Erika Barbosa , Sousa Paulo Henrique Alves , Resende Karolyne Araujo , Santos Letícia Camilo , Silva Luiz Henrique Rodrigues , Belo Vinícius Silva , Romano Márcia Christina Caetano 
Published: March 2021

Objective. To assess the relationship between the nutritional status and eating habits of children aged from five to ten years old and their mothers, living in rural areas.
Methods. A cross-sectional study conducted with 156 children aged from five to ten years old, registered in the Family Health Strategies of the rural area of the Municipality of Divinópolis-MG (Brazil) from July 2017 to April 2018.
Results. The prevalence of excess weight was 27.5%. The following parameters were significantly associated with excess weight in the children: maternal waist circumference (OR=1.04), protein consumption (OR=1.02), irregular consumption of natural juice (OR=5.05), and the most favored socioeconomic level, C1 social stratum (OR=3.54). Regarding the correlation between nutrient intake of the children and their mothers, most of the correlations were weak to moderate, being statistically significant for all the dietary components evaluated (r=0.185 to 0.496).
Conclusion. Maternal nutritional status was related to the child’s excess weight and a weak to moderate correlation was observed for nutrient intake among the children and their mothers. A high prevalence of children with excess weight was observed in the rural areas. The results point to the need to implement collective approaches, targeted at rural families, so as to prevent this problem.
FENOLOGIA REPRODUTIVA DE Lychnophora pohlii Sch. Bip. (ASTERACEAE) EM ÁREA DE CAMPO RUPESTRE, DIAMANTINA, MG.
Authors: Costa Thaí­s Ribeiro , De Moura Cristiane Coelho , Machado Evandro Luiz Mendonça , Gonzaga Allanne Pillar Dias , Titon Miranda 
Published: March 2021

Considerando que o conhecimento da fenologia de espécies vegetais em comunidades naturais é uma ferramenta importante para a conservação das populações e ecossistemas, esse estudo teve como objetivo compreender a fenologia reprodutiva da espécie Lychnophora pohlii, associando as estratégias reprodutivas s variações sazonais caracterí­sticas do ambiente. O estudo foi realizado em uma área de campo rupestre pertencente ao Campus JK, na UFVJM, em Diamantina, MG. Foram observadas as caracterí­sticas fenológicas de 26 plantas, no perí­odo de maio de 2012 a fevereiro de 2013. Foram utilizados dados meteorológicos de precipitação e temperatura durante o perí­odo de estudo. O padrão fenológico foi determinado pelo método de intensidade de Fournier, correlação de Spearman e análise circular. Foram encontradas correlações significativas entre as fenofases e as variáveis abióticas. A espécie apresentou umcomportamento fenológico bastante sazonal, reflexo da sazonalidade climática, caracterí­stica da região de estudo.
NOVA ESPÉCIE DE OCOTEA AUBL. PARA A REGIÃO NEOTROPICAL, ESTADOS DE SÃO PAULO E RIO DE JANEIRO, BRASIL.
Authors: Baitello João Batista , Brotto Marcelo Leandro 
Published: March 2021

Descreve-se uma nova espécie de Lauraceae para a região neotropical, sudeste do Brasil, estados de São Paulo e Rio de Janeiro. Ocotea koscinskii Baitello & Brotto é espécie unissexuada semelhante a Ocotea dispersa (Nees) Mez, mas difere desta, em especial, pela forma globosa do fruto e ausência de tépalas remanescentes na cúpula e, inflorescência tirsoidepaniculada. Diferem entre si ainda pelas ocorrências em estratos diferentes quando coexistem na Floresta Ombrófila Densa, respectivamente dossel e subbosque.
A ARBORIZAíâ?¡ÃO E SEUS CONFLITOS NO BAIRRO JARDIM DOS ESTADOS, POíâ?¡OS DE CALDAS - MG
Authors: Menezes Leda Carolina Carvalho , Tavares Raí­ssa , Botezelli Luciana 
Published: March 2021

O presente estudo consiste no levantamento e análise da arborização de um trecho do Bairro Jardim dos Estados, no municí­pio de Poços de Caldas - MG, tendo como objetivo diagnosticar e mapear os indiví­duos arbóreos presentes na área pública e os conflitos existentes com estruturas urbanas. O processo de arborização é considerado uma estratégia para amenização de impactos ambientais e está associado manutenção da qualidade de vida. Na área estudada foram encontrados através de estudo de campo, 204 indiví­duos, de 30 espécies, pertencentes a 18 famí­lias. A espécie mais frequente foi a quaresmeira (Pleroma granulosa (Desr.) D. Don), representada por 31,86% dos indiví­duos. O conflito com a rede elétrica foi o mais recorrente (68,63%). Foram encontradas no trecho estudado: 26,7% de espécies nativas; 16,7% de espécies nativas do Brasil, mas não da área estudada; 53,3% de espécies exóticas e 3,3% de espécies naturalizadas. Dentre as soluções para conflitos desta natureza, estão o planejamento da arborização, a adequada manutenção, condução dos indiví­duos no pós-plantio e a adaptação das estruturas urbanas ao ambiente.
DIVERSIDADE DA FLORA FANEROGíâ??MICA DE TRíÅ S MATAS DE GALERIA NO BIOMA CERRADO
Authors: Bambi Paulino , Rezende Renan de Souza , Cruz Takumâ Machado Scarponi , Batista Juan Enrique de Araújo , Miranda Fernanda Gabriela Graciano , Vieira dos Santos Lauana , Gonçalves Júnior José Francisco 
Published: March 2021

O objetivo deste estudo foi avaliar a diversidade vegetal de fanerógamas em três matas de galeria no Distrito Federal, Brasil. O estudo foi realizado na Área de Proteção Ambiental Gama-Cabeça de Veado, a partir do levantamento fitossociológico em 12 parcelas paralelas aos córregos das matas de galerias amostradas, totalizando 3600 m2 de área. Foram identificadas 146 espécies, sendo Fabaceae, Myrtaceae e Rubiaceae as famí­lias mais representativas. Apenas sete espécies ocorreram concomitantemente nas áreas estudadas, indicando elevada diversidade, sobretudo em termos de árvores e arbustos. Os valores de riqueza de espécies e diversidade de Shannon foram maiores no córrego Cabeça-de-Veado (JBB), comparado ao córrego Capetinga (FAL) e Roncador (IBGE), respectivamente. Enquanto que a Dominância Absoluta apresentou maiores valores no córrego Roncador, comparado aos córregos Capetinga e Cabeça-de-Veado, respectivamente. Assim, observamos que a diversidade de espécies está relacionada heterogeneidade ambiental das matas amostradas, as quais estão relacionadas as caracterí­sticas edáficas e do regime hidrológico.