bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation of Passive Daytime Cooling Fabric with the Synergistic Effect of Radiative Cooling and Evaporative Cooling
Authors: Sun Yilan , Ji Yating , Javed Muhammad , Li Xiaoyan , Fan Zhuizhui , Wang Youquan , Cai Zaisheng , Xu Bi 
Published: October 2021

AbstractPassive daytime radiative cooling (PDRC) has attracted intensive attention due to its great potential in reduced energy consumption. However, the practical application for PDRC is greatly affected by geographical location and the intrinsic cooling power. Herein, a composite flexible fabric with the synergistic effect of evaporative cooling and radiative cooling is reported. A porous polymer coating with both a high solar reflectivity (90%) and a high infrared thermal emissivity (83%) is fabricated on the top side of the fabric, which can achieve effective PDRC performance. Meanwhile, hygroscopic salts are loaded on the bottom side of the fabric, which can capture water vapor at night and realize evaporative cooling during the daytime. The temperature reduction of 10.8 °C can be achieved under the direct sunlight irradiation (465 W m−2) for the prepared fabric in the outdoor experiment. The combination of radiative cooling and evaporative cooling breaks through the traditional single passive cooling mode and has great potential in further improving the performance of passive cooling.
Room Temperature VOCs Sensing with Termination‐Modified Ti3C2Tx MXene for Wearable Exhaled Breath Monitoring
Authors: Li Xin , An Zijian , Lu Yanli , Shan Jianzhen , Xing Huan , Liu Guang , Shi Zhenghan , He Yan , Chen Qingmei , Han Ray P. S. , Wang Di , Jiang Jing , Zhang Fenni , Liu Qingjun 
Published: October 2021

AbstractRoom temperature volatile organic compounds (VOCs) sensors usually suffer from severe humidity interference and insufficient sensitivity against VOCs, which greatly restricts its practical applications. Herein, the authors simultaneously reduce the hydrophilicity while improving the VOCs sensitivity of Ti3C2Tx MXene by introducing hydrocarbon terminations. The termination‐modified Ti3C2Tx (Ti3C2Tx‐M2) sensor demonstrates fivefold enhancement in ethanol sensitivity at room temperature, while response against water vapor has been reduced by 71% compared with pristine Ti3C2Tx. In addition, the modification also contributes to the arrest of sensor degradation that refines the sensing stability. On this basis, the MXene‐based VOCs sensor is employed for in situ, real‐time monitoring of exhaled ethanol as a proof‐of‐concept by integrating it with a wearable detection tag. Owing to the suppressed humidity interference and amplified VOCs response, the Ti3C2Tx‐M2 sensor could dynamically track the exhaled ethanol variations after alcohol intake. This work not only demonstrates a facile modification strategy to promote the sensitivities of MXene‐based VOCs sensor, but also a promising scheme for facile breath analysis, shedding lights on MXene‐based wearable medical electronics and intelligent healthcare.
Self‐Host Thermally Activated Delayed Fluorescence Material with Aggregation‐Induced Emission Character: Multi‐Functional Applications in OLEDs
Authors: Dong Ruizhi , Li Jiuyan , Liu Di , Li Deli , Mei Yongqiang , Ma Mengyao , Jiang Jingyang 
Published: October 2021

AbstractThermally activated delayed fluorescence (TADF) materials that can exhibit high efficiencies in non‐doped organic light‐emitting diodes (OLEDs) are highly desired. On the base of a reference TADF molecule (4‐(9,9‐dimethylacridin‐10(9H)‐yl)phenyl)(phenyl)methanone (BP‐DMAC) containing benzoyl/acridine as acceptor/donor, 9‐phenyl‐9H‐3,9“‐bicarbazole (PBCz) is incorporated to the benzoyl side to design and develop a novel emitter, (4‐(9,9‐dimethylacridin‐10(9H)‐yl)phenyl)(9‐phenyl‐9H‐[3,9″‐bicarbazol]‐6‐yl)methanone (PBCz‐BP‐DMAC). The introduction of PBCz unit is proved to endow PBCz‐BP‐DMAC the additional self‐host feature, in addition to its original aggregation‐induced emission and TADF characters. As a result, the non‐doped OLED of PBCz‐BP‐DMAC exhibits sky‐blue emission with remarkable external quantum efficiency (EQE) of 23.0% and rather low efficiency roll‐off (6%) at a brightness of 1000 cd m−2, while its doped device reveals a maximum EQE of 27.5%; the spectra and color coordinates of the doped and non‐doped devices are almost identical. It also acts as a host to sensitize green iridium phosphor (fac‐tris(2‐phenylpyridine) iridium(III), Ir(ppy)3) with high EQE of 23.6%. More fascinatingly, the simplified single‐emitting‐layer all‐TADF white OLED utilizing PBCz‐BP‐DMAC as host emitter in combination with an orange TADF emitter (4CzTPN‐Ph) realizes a state‐of‐the‐art EQE of 20.6%. Evidently PBCz‐BP‐DMAC is one of the best sky‐blue TADF materials and exhibits multi‐functional applications in OLEDs with excellent performance.
Observation of Room‐Temperature Dark Exciton Emission in Nanopatch‐Decorated Monolayer WSe2 on Metal Substrate
Authors: Rahaman Mahfujur , Selyshchev Oleksandr , Pan Yang , Schwartz Rico , Milekhin Ilya , Sharma Apoorva , Salvan Georgeta , Gemming Sibylle , Korn Tobias , Zahn Dietrich R. T. 
Published: October 2021

AbstractThe presence of strong spin–orbit coupling in the valence band and weak spin‐splitting in the conduction band result in the lowest energy exciton in WX2 (X = S, Se) being spin forbidden and optically dark. Because of their long lifetimes, dark excitons are highly attractive for quantum optics and optoelectronic applications. To date, studying dark excitonic emissions is limited to cryogenic temperatures or requires very complex experimental configurations to observe them at room temperature (RT). Here, the radiative decay of dark exciton related emission in WSe2 monolayers is studied using both conventional and tip‐enhanced photoluminescence (TEPL) at RT. Monolayer WSe2 flakes are sandwiched between noble metal substrates and polydimethylsiloxane nanopatches providing a strong local electrostatic out‐of‐plane dipole moment with respect to the 2D plane resulting in the observation of dark excitonic emission at RT. The spatial distribution of this dark exciton related emission is studied by TEPL with a spatial resolution of <10 nm confirming the confinement of these excitons within the polydimethylsiloxane nanopatches. The tip‐enhanced Raman scattering (TERS) investigation excludes any local strain induced effects and reveals a direct correlation between dark excitons and defects in WSe2. Finally, removal of the nanopatches led to the recovery of bright excitonic emission in WSe2.
Unconventional Resistive Switching Behavior in Fibroin‐Based Memristor
Authors: Chang Ke , Dong Anhua , Yu Xinna , Liu Binbin , Zhao Xinhui , Wang Renzhi , Gan Zhikai , Jiang Kang'an , Niu Yiru , Dong Xinyuan , Zheng Diyuan , Li Yizhen , Bao Peng , Zhao Zhuyikang , Wang Hui 
Published: October 2021

AbstractTransient memristor, which can be decomposed in water after completing the designed task, has shown great potentials in data security, implantable medical devices, and eco‐friendly electronics. However, the further development of transient memristors is hindered by lacking practical approaches to deal with the dilemma between stability and degradability of the device. Here, using Ag‐doped fibroin film as a switching medium, an unconventional right‐angled‐like resistive switching behavior is observed. Based on this novel resistive switching characteristic, a high‐performance transient memristor is designed and fabricated. A self‐assembled Ag nanoclusters model is proposed to interpret this unique electron‐transport property. The self‐assembled silver nanoclusters can redistribute the charge flux and lower the potential barrier, leading to novel switching characteristics. Furthermore, the device can work at ultralow operating voltages (0.03 V) over 300 cycles with an extremely high memory window of 107. The experimental findings open up a new path to design high‐performance transient memristors for a safe and reliable data storage system.
Combined UAV‐ and tractor‐based stripe rust monitoring in winter wheat under field conditions
Authors: Dammer Karl‐Heinz , Garz Andreas , Hobart Marius , Schirrmann Michael 
Published: October 2021

AbstractUnmanned aerial vehicles (UAVs) have the potential to monitor the health status of several crop fields of a farmer in full coverage. For a complete and fast monitoring, however, high flight altitudes are usually needed, especially if large areas should be observed in short time intervals. In this case, the resolution on the ground becomes insufficient to detect specific symptoms of crop diseases because a ground resolution in the submillimeter scale is needed. This study pursued the idea of performing remote UAV imaging to detect discoloration in combination with near‐surface tractor imaging to detect the uredospore layers as characteristic signs of stripe (yellow) rust (caused by Puccinia striiformis Westend. f. sp. tritici) in winter wheat (Triticum aestivum L.). To simulate healthy and diseased field parts, the 3‐yr experimental design included controlled infected plots and those sprayed with fungicides as healthy controls. Imaging, disease severity, and crop development rating were performed along a time series. Significant differences between infected and control plots occurred in the UAV imagery using the normalized green–red difference index from a median (upper three leaves) infested leaf area of 3% and for the tractor images using the maximally stable extreme regions detector from 3 and 5%, respectively. In the future, it is conceivable that farmers will combine UAV (aerial monitoring of crop damage of complete fields) and tractor (ground monitoring to determine the cause) imaging for automatic scanning of the health status.
Effects of continuous cropping on soil, senescence, and yield of Tartary buckwheat
Authors: Zhang Yu , Guo Rongyu , Li Shihong , Chen Yan , Li Zhendong , He Peiyun , Huang Xiaoyan , Huang Kaifeng 
Published: October 2021

AbstractThe yield of Tartary buckwheat (Fagopyrum tataricum Gaertn) is significantly affected by continuous cropping. This study aimed to clarify the effects of continuous cropping on the growth and yield formation of Tartary buckwheat. Tartary buckwheat cultivar Jinqiao was used as the experimental material to study the effects of different continuous cropping years on the rhizosphere soil, root morphology and physiology, senescence, and yield of Tartary buckwheat. Available nutrients, number of actinomycetes, soil enzyme activities, and contents of total chlorophyll and soluble protein in the leaves of Tartary buckwheat continuously decreased with an increase in continuous cropping years. However, the pH and number of fungi showed a continuous increasing trend. The number of bacteria in rhizosphere soil, root morphological indexes and root activity, and oxidase activity of the leaves initially increased and then decreased. Compared with that of the control, the yield of Tartary buckwheat significantly reduced by 6.36, 24.85, 78.62, and 83.10% with 1, 2, 3, and 4 yr of continuous cropping, respectively. Therefore, continuous cropping reduces the yield of Tartary buckwheat by destroying the microenvironment system of rhizosphere soil, inhibiting the growth and development of the root and shoot systems, and accelerating senescence.
Splenectomy for primary immune thrombocytopenia revisited in the era of thrombopoietin receptor agonists: New insights for an old treatment
Authors: Mageau Arthur , Terriou Louis , Ebbo Mikael , Souchaud‐Debouverie Odile , Orvain Corentin , Graveleau Julie , Lega Jean‐Christophe , Ruivard Marc , Viallard Jean‐François , Cheze Stéphane , Dossier Antoine , Bonnotte Bernard , Perlat Antoinette , Gobert Delphine , Costedoat‐Chalumeau Nathalie , Jeandel Pierre‐Yves , Dernoncourt Amandine , Michel Marc , Godeau Bertrand , Comont Thibault 
Published: October 2021

AbstractAlthough splenectomy is still considered the most effective curative treatment for immune thrombocytopenia (ITP), its use has significantly declined in the last decade, especially since the approval of thrombopoietin receptor agonists (TPO‐RAs). The main objective of the study was to determine whether splenectomy was still as effective nowadays, particularly for patients with failure to respond to TPO‐RAs. Our secondary objective was to assess, among patients who relapsed after splenectomy, the pattern of response to treatments used before splenectomy. This multicenter retrospective study involved adults who underwent splenectomy for ITP in France from 2011 to 2020. Response status was defined according to international criteria. We included 185 patients, 100 (54.1%) and 135 (73.0%) patients had received TPO‐RAs and/or rituximab before the splenectomy. The median follow‐up after splenectomy was 39.2 months [16.5–63.0]. Overall, 144 (77.8%) patients had an initial response and 23 (12.4%) experienced relapse during follow‐up, for an overall sustained response of 65.4%, similar to that observed in the pre‐TPO‐RA era. Among patients who received at least one TPO‐RA or rituximab before splenectomy, 92/151 (60.9%) had a sustained response. Six of 13 (46%) patients with previous lack of response to both TPO‐RAs and rituximab had a sustained response to splenectomy. Among patients with relapse after splenectomy, 13/21 (61.2%) patients responded to one TPO‐RAs that failed before splenectomy. In conclusion, splenectomy is still a relevant option for treating adult primary ITP not responding to TPO‐RAs and rituximab. Patients with lack of response or with relapse after splenectomy should be re‐challenged with TPO‐RAs.
Chimeric antigen receptor T‐cells, bispecific antibodies, and antibody‐drug conjugates for multiple myeloma: An update
Authors: Lakshman Arjun , Kumar Shaji K. 
Published: October 2021

AbstractPatients with multiple myeloma who are refractory to currently available effective therapies have short expected survival. Modalities harvesting the knowledge of the immune characteristics and microenvironment of myeloma such as chimeric antigen receptor (CAR) T‐lymphocytes, bispecific antibodies (bsAbs), and antibody‐drug conjugates (ADCs) have shown potential in early phase trials. Based on data from phase 2 studies, idecabtagene vicleucel (ide cel), an anti‐B‐cell maturation antigen CAR T‐product and belantamab mafodotin (belamaf), an ADC are currently approved in the relapsed/refractory setting. bsAbs have shown promise with quick and deep responses. In this review, we summarize the available evidence on these treatments from clinical trials.
Catalytic Asymmetric Strecker Reaction of Ketoimines with Potassium Cyanide
Authors: Ohmatsu Kohsuke , Morita Yusuke , Kiyokawa Mari , Hoshino Kimihiro , Ooi Takashi 
Published: October 2021

AbstractA catalytic asymmetric Strecker reaction of ketoimines with potassium cyanide (KCN) is developed. Control experiments reveal the involvement of a retro‐Strecker reaction, which inevitably decreases the product yield and enantioselectivity. The use of a protic additive in combination with a chiral 1,2,3‐triazolium ion as a catalyst allows for the highly efficient and enantioselective cyanide addition to various ketoimines.
Na2S2O8‐Mediated Tandem One‐Pot Construction of 3,3‐Disubsituted 3,4‐Dihydroquinoxalin‐2(1H)‐ones with 4‐Alkyl‐1,4‐dihydropyridines as Alkyl Radical Sources
Authors: Yao Zhen , Zhang Xin , Luo Zhenli , Pan Yixiao , Zhao Haoqiang , Li Bohan , Xu Lijin , Shi Qian , Fan Qing‐Hua 
Published: October 2021

AbstractTandem one‐pot synthesis of 3,3‐disubstituted 3,4‐dihydroquinoxalin‐2(1H)‐ones bearing a quaternary carbon center from readily available 1,2‐diaminobenzenes, α‐ketoesters and 4‐alkyl‐1,4‐dihydropyridines mediated by cheap and stable Na2S2O8 has been achieved. This transition‐metal‐free protocol operates under mild thermal conditions, delivers high product yields for a wide variety of substrates and displays good compatibility with diverse functional groups and facile scalability. Choosing a suitable oxidant and an acid additive is very crucial for the success of this transformation. Mechanistic investigations provide evidence for the involvement of a radical chain mechanism.
In Situ Modulation of A‐Site Vacancies in LaMnO3.15 Perovskite for Surface Lattice Oxygen Activation and Boosted Redox Reactions
Authors: Liu Xiaoqing , Mi Jinxing , Shi Lin , Liu Haiyan , Liu Jun , Ding Yun , Shi Jianqiang , He Minghua , Wang Zisha , Xiong Shangchao , Zhang Qinfang , Liu Yuefeng , Wu Zhong‐Shuai , Chen Jianjun , Li Junhua 
Published: October 2021

AbstractModulation of A‐site defects is crucial to the redox reactions on ABO3 perovskites for both clean air application and electrochemical energy storage. Herein we report a scalable one‐pot strategy for in situ regulation of La vacancies (VLa) in LaMnO3.15 by simply introducing urea in the traditional citrate process, and further reveal the fundamental relationship between VLa creation and surface lattice oxygen (Olatt) activation. The underlying mechanism is shortened Mn−O bonds, decreased orbital ordering, promoted MnO6 bending vibration and weakened Jahn–Teller distortion, ultimately realizing enhanced Mn‐3d and O‐2p orbital hybridization. The LaMnO3.15 with optimized VLa exhibits order of magnitude increase in toluene oxidation and ca. 0.05 V versus RHE (reversible hydrogen electrode) increase of half‐wave potential in oxygen reduction reaction (ORR). The reported strategy can benefit the development of novel defect‐meditated perovskites in both heterocatalysis and electrocatalysis.
Chemoenzymatic conversion of furfural to methyl‐2‐furotate
Authors: Song Miaojia , Lu Jianping , Zhang Yu , Sun Yongming , Yuan Zhenhong , Wang Zhongming 
Published: October 2021

AbstractFurfural (FF) is an important bio‐based platform compound derived from lignocellulose. It can be converted into many industrially valuable chemicals, a typical one being methyl‐2‐furoate (MF). At present, MF production depends largely on vigorous one‐step chemical catalysis (oxidative esterification), in which expensive catalysts (precious metals) and a high temperature (60–120 °C) are required. To reduce the costs of this procedure, a mild, green, and cheap chemoenzymatic process is proposed where FF is initially chemically oxidized to furoic acid (FA), and then FA is enzymatically esterified to MF. Neither step requires an expensive catalyst, and both occur at low temperatures (30–50 °C). For the chemical oxidation process, the optimized FA yield of 83.7% was obtained at 40 °C with an FF/BTIC (1,3‐bis(2,4,6‐trimethylphenyl) imidazolium chloride) molar ratio of 0.18, 10 mL N‐methyl pyrrolidone, and 0.1 MPa oxygen pressure. For the enzymatic esterification, the optimized MF yield reached 80.6% at 50 °C with 50 mg•mL−1 enzyme loading and an alcohol/acid ratio of 7:1. Kinetic studies demonstrated the oxidation to be a sixth‐order reaction, and the esterification to be an endothermic reaction. For both oxidation and esterification reactions, the relationship between the rate constant and temperature agreed well with the Arrhenius equation. For esterification, the relationship between the equilibrium constant and the temperature also agreed with the Van't Hoff equation. A 67.5% MF yield was obtained when sequential oxidation and esterification were initiated from FF. The development of chemoenzymatic processes for MF production from FF is effective and has potential value in decreasing the production cost of MF. © 2021 Society of Chemical Industry and John Wiley & Sons, Ltd
Hyperthermia ablation combined with transarterial chemoembolization versus monotherapy for hepatocellular carcinoma: A systematic review and meta‐analysis
Authors: Li Zheng , Li Qiang , Wang Xiaohu , Chen Weiqiang , Jin Xiaodong , Liu Xinguo , Ye Fei , Dai Zhongying , Zheng Xiaogang , Li Ping , Sun Chao , Liu Xiongxiong , Zhang Qiuning , Luo Hongtao , Liu Ruifeng 
Published: October 2021

AbstractBackground and aimsThe existing evidence has indicated that hyperthermia ablation (HA) and HA combined with transarterial chemoembolization (HATACE) are the optimal alternative to surgical resection for patients with hepatocellular carcinoma (HCC) in the COVID‐19 crisis. However, the evidence for decision‐making is lacking in terms of comparison between HA and HATACE. Herein, a comprehensive evaluation was performed to compare the efficacy and safety of HATACE with monotherapy.Materials and MethodsWorldwide studies were collected to evaluate the HATACE regimen for HCC due to the practical need for global extrapolation of applicative population. Meta‐analyses were performed using the RevMan 5.3 software (The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark).ResultsThirty‐six studies involving a large sample of 5036 patients were included finally. Compared with HA alone, HATACE produced the advantage of 5‐year overall survival (OS) rate (OR:1.90; 95%CI:1.46,2.46; p < 0.05) without increasing toxicity (p ≥ 0.05). Compared with TACE alone, HATACE was associated with superior 5‐year OS rate (OR:3.54; 95%CI:1.96,6.37; p < 0.05) and significantly reduced the incidences of severe liver damage (OR:0.32; 95%CI:0.11,0.96; p < 0.05) and ascites (OR:0.42; 95%CI:0.20,0.88; p < 0.05). Subgroup analysis results of small (≤3 cm) HCC revealed that there were no significant differences between the HATACE group and HA monotherapy group in regard to the OS rates (p ≥ 0.05).ConclusionsCompared with TACE alone, HATACE was more effective and safe for HCC. Compared with HA alone, HATACE was more effective for non‐small‐sized (>3 cm) HCC with comparable safety. However, the survival benefit of adjuvant TACE in HATACE regimen was not found for the patients with small (≤3 cm) HCC.
Hydroxycinnamic Acid Amide Dimers from Goji Berry and Their Potential Anti‐AD Activity
Authors: Chai Tian , Zhang Wen‐Han , Jiao Hui , Qiang Yin 
Published: October 2021

AbstractThree undescribed hydroxycinnamic acid amide dimers 1–3 were isolated and identified from an extract of Goji berry. Their molecular structures were elucidated based on NMR, MS, and IR spectra analysis. Compounds 1–3 were hydroxycinnamic acid amide dimers, which possess a cyclic butane moiety formed by head‐to‐head connection. These compounds at 25 μM showed the disaggregation potency on the copper‐mediated Aβ1‐42 aggregation ranging from 27.3±3.2 to 31.0±2.9 %. This study provides new information on the antiaging traditional usage of goji berry.
Synthetic Aurones: New Features forSchistosoma mansoniTherapy
Authors: Silva Torres Daniel , Alves de Oliveira Bruna , Souza d Silveira Lígia , Paulo da Silva Marcos , Rodrigues Durães Pereira Vinícius , Moraes Josué , Rúbia Costa Couri Mara , Fortini Grenfell e Queiroz Rafaella , Martins Parreiras Patrícia , Roberto Silva Márcio , Azevedo Alves Lara , Carius de Souza Vinícius , Vanessa Zabala Capriles Goliatt Priscila , Gomes Vasconcelos Eveline , Alves da Silva Filho Ademar , de Faria Pinto Priscila 
Published: October 2021

AbstractIn this work, two synthetic aurones revealed moderate schistosomicidal potential inin vitroandin vivoassays. Aurones (1) and (2) promoted changes in tegument integrity and motor activity, leading to death of adultSchistosoma mansoniworms inin vitroassays. When administered orally (two doses of 50 mg/kg) in experimentally infected animals, synthetic aurones (1) and (2) promoted reductions of 56.20 % and 57.61 % of the parasite load and stimulated the displacement towards the liver of the remaining adult worms. The oogram analysis revealed that the treatment with both aurones interferes with the egg development kinetics in the intestinal tissue. Seeking an action target for compounds (1) and (2), the connection with NTPDases enzymes, recognized as important therapeutic targets forS. mansoni, was evaluated. Molecular docking studies have shown promising results. The dataset reveals the anthelmintic character of these compounds, which can be used in the development of new therapies for schistosomiasis.