bluuebunny/crossref_metadata_2025_split huggingface dataset:
Density distribution investigation through the geometrical structure for the 27S halo nucleus
Authors: Islam J , Radiman S , Khoo K S. 
Published: March 2021

Abstract

27S was predicted as a proton halo nucleus in the 2s1/2 state due to the abnormally large protons root mean square radius. The presence of weakly bound (S2n = 0.90(20) MeV) two valence protons in the 27S nucleus strongly supported this prediction. The core density, matter density, and halo density for this nucleus (27S) have been investigated in this study. The geometrical halo structure has been used for different parameter calculations to investigate these density distributions since sufficient experimental data are not available for this 27S nucleus. The parameters’ values were calculated easily following this geometrical structure. Gaussian-Gaussian (GG) distribution has been applied to investigate these densities. In our present study, the 27S nucleus was investigated as a 2-p halo nucleus due to its low valence two-protons separation energy (0.90 MeV). The 2-p halo 27S nucleus was described having (25Si) + p + p configuration. These measured parameters’ values were then used to investigate the Gaussian-Gaussian (GG) density distributions. MATLAB computational software was also used for these distribution investigations. From these density distributions, a maximum density of 1.042%, 1.001%, and 0.4789% at the centre of the nucleus was obtained for the core density (ρc
), matter density (ρm
), and halo density (ρh
), respectively. The presence of longer tails on the halo and matter distributions also support the prediction as a two-proton halo nucleus.
Development of gantry radial arm robotic system for corrosion inspection on wall of reactor tank TRIGA
Authors: Ramli R , Sani S , Asri A S 
Published: March 2021

Abstract
This paper focuses on the design upgrade of existing scanner of gantry radial arm robotic system for corrosion inspection on wall reactor of a TRIGA tank. The scanner design will be used for under water inspection environment verification. This inspection can be performed by using ultrasonic C-scan that will be designed in this project. This gantry radial arm system is a modular design that allows upgrading, easy dimensional matching and, specifications related to kinematic and technique. The gantry radial arm system is expected to be user-friendly. SolidWorks software was used to design the prototype of the gantry radial arm. Most of the components are made from Aluminium which is much sturdy and low cost. Meanwhile for the rod holder system, spring mechanism was used to prevent rod from bending when it moves down into the water. The test results show that the system designed is safe to be used, as it has been proved by simulation and calculation.
COVID-19 detection from lung CT-scan images using transfer learning approach
Authors: Halder Arpita , Datta Bimal 
Published: March 2021

Abstract
Since the onset of 2020, the spread of coronavirus disease (COVID-19) has rapidly accelerated worldwide into a state of severe pandemic. COVID-19 has infected more than 29 million people and caused more than 900 thousand deaths at the time of writing. Since it is highly contagious, it causes explosive community transmission. Thus, health care delivery has been disrupted and compromised by the lack of testing kits. COVID-19-infected patients show severe acute respiratory syndrome. Meanwhile, the scientific community has been involved in the implementation of deep learning (DL) techniques to diagnose COVID-19 using computed tomography (CT) lung scans, since CT is a pertinent screening tool due to its higher sensitivity in recognizing early pneumonic changes. However, large datasets of CT-scan images are not publicly available due to privacy concerns and obtaining very accurate models has become difficult. Thus, to overcome this drawback, transfer-learning pre-trained models are used in the proposed methodology to classify COVID-19 (positive) and COVID-19 (negative) patients. We describe the development of a DL framework that includes pre-trained models (DenseNet201, VGG16, ResNet50V2, and MobileNet) as its backbone, known as KarNet. To extensively test and analyze the framework, each model was trained on original (i.e. unaugmented) and manipulated (i.e. augmented) datasets. Among the four pre-trained models of KarNet, the one that used DenseNet201 demonstrated excellent diagnostic ability, with AUC scores of 1.00 and 0.99 for models trained on unaugmented and augmented data sets, respectively. Even after considerable distortion of the images (i.e. the augmented dataset) DenseNet201 achieved an accuracy of 97% for the test dataset, followed by ResNet50V2, MobileNet, and VGG16 (which achieved accuracies of 96%, 95%, and 94%, respectively).
Function of the TRY C-terminal region artificially fused with its homologous transcription factors inducing root hair differentiation in Arabidopsis
Authors: Wakamatsu Juri , Nagao Kosuke , Sumida Yukino , Tanaka Wakana , Sambongi Yoshihiro , Tominaga Rumi 
Published: March 2021

ABSTRACT
TRIPTYCHON (TRY) is one of the R3-MYB transcription factors. Its extended C-terminal 19 amino-acid region (CTRY) is considered to affect the ability of root hair differentiation in Arabidopsis. Here, to further understand the function of CTRY, it, together with GFP, was artificially fused with TRY homologs, CPC and ETC1, which do not contain such extended regions and induce root hair differentiation. Arabidopsis transgenic plants carrying the fusion proteins, CPC-CTRY-GFP and ETC1-CTRY-GFP, induced root hair differentiation as observed in those carrying the original proteins without CTRY. The expression levels of the fusion proteins in the transgenic plants were essentially the same as those of the original proteins, although their subcellular localization to nuclei of root epidermal cells was slightly changed by CTRY. Therefore, CTRY does not affect the ability of CPC and ETC1 to induce root hair differentiation when artificially fused, and its function may be restricted in TRY.
Dysfunctional Brain Reward System in Child Obesity
Authors: Pujol Jesus , Blanco-Hinojo Laura , Martínez-Vilavella Gerard , Deus Joan , Pérez-Sola Víctor , Sunyer Jordi 
Published: March 2021

Abstract
Eating habits leading to obesity may reflect nonhomeostatic behavior based on excessive immediate-reward seeking. However, it is currently unknown to what extent excess weight is associated with functional alterations in the brain’s reward system in children. We tested the integrity of reward circuits using resting-state functional connectivity magnetic resonance imaging in a population of 230 children aged 8–12 years. The major components of the reward system were identified within the ventral striatum network defined on the basis of the nucleus accumbens connectivity pattern. The functional structure of the cerebral cortex was characterized using a combination of local functional connectivity measures. Higher body mass index was associated with weaker connectivity between the cortical and subcortical elements of the reward system, and enhanced the integration of the sensorimotor cortex to superior parietal areas relevant to body image formation. Obese children, unlike WHO-defined overweight condition, showed functional structure alterations in the orbitofrontal cortex and amygdala region similar to those previously observed in primary obsessive–compulsive disorder and Prader–Willi syndrome associated with obsessive eating behavior. Results further support the view that childhood obesity is not simply a deviant habit with restricted physical health consequences but is associated with reward system dysfunction characterizing behavioral control disorders.
Medea and other women in Jules Dassin’s Never on Sunday
Authors: Sermamoglou-Soulmaidi Georgia 
Published: March 2021

Abstract
In Jules Dassin’s 1960’s film Never on Sunday, Ilia is a Greek prostitute at the port of Piraeus, who is very fond of Greek tragedy. Yet, while she has seen Euripides’ Medea fifteen times, she keeps denying that, at the end of the play, Medea kills her children. This article explores the reasons why Ilia insists on seeing the play again and again, while also insisting on recasting a revenge plot into a love story with a happy ending. Furthermore, it discusses gender dynamics in the film, focusing on Ilia’s firm opposition to all female oppression. Finally, it argues that, through Ilia’s misinterpretation of Medea, Never on Sunday invites discussion of the various disguises of human vulnerability and of an all too common fear—the fear of love.
Pre-operative glycaemic control and long-term survival in diabetic patients after coronary artery bypass grafting
Authors: Deo Salil , Sundaram Varun , Sheikh Muhammad Adil , Sahadevan Jayakumar , Selvaganesan Padmini , Madan Mohan Sri Krishna , Rubelowsky Joseph , Elgudin Yakov , Josephson Richard , Davierwala Piroze M , Cmolik Brian 
Published: March 2021

Abstract

OBJECTIVES
We analysed the Veteran Affairs data to evaluate the association of pre-operative glycated haemoglobin (HbA1c) and long-term outcome after isolated coronary artery bypass grafting (CABG).

METHODS
Veterans with diabetes mellitus and isolated CABG (2006–2018) were divided into 4 groups (I: HbA1c &lt;6.5%, II: HbA1c 6.5–8, III 8–10% and IV: HbA1c &gt;10%). The relationship of pre-operative HbA1c and long-term survival was evaluated with a multivariable Cox proportional hazards model and reported as hazard ratios (HR). The cumulative incidence of secondary end-points [myocardial infarction (MI) and repeat revascularization (percutaneous intervention)] for each group was modelled as competing events with cause-specific Cox proportional hazards models.

RESULTS
Overall, 16 190 patients (mean age 64.9 years, male 98%; insulin dependent 53%) with diabetes mellitus underwent isolated CABG. We observed 19.4%, 45.4%, 27% and 8.2% patients in groups I, II, III and IV, respectively. Patients with HbA1c &gt;10% were the youngest (mean age 60.9 years) and had high rates of Insulin dependence (78%). In patients with HbA1c &gt;10%, improvement in levels was observed in 76%. The median follow-up observed was 5.8 (3.2–8.8) years. Compared to the study mean HbA1c (7.3%), mortality rate increased with HbA1c levels &gt;8%, and especially with pre-operative HbA1c levels &gt;9%. Compared to patients with HbA1c &lt;8%, HbA1c 8–10% and &gt;10% were associated with increased MI (HR 1.24 and HR 1.39, respectively) and need for reintervention (HR 1.20 and HR 1.24, respectively).

CONCLUSIONS
In patients undergoing CABG, pre-operative HbA1c &gt;8% is associated with the increased risk of mortality and adverse cardiac events.
The new COST Action European Venom Network (EUVEN)—synergy and future perspectives of modern venomics
Authors: Modica Maria Vittoria , Ahmad Rafi , Ainsworth Stuart , Anderluh Gregor , Antunes Agostinho , Beis Dimitris , Caliskan Figen , Serra Mauro Dalla , Dutertre Sebastien , Moran Yehu , Nalbantsoy Ayse , Oukkache Naoual , Pekar Stano , Remm Maido , von Reumont Bjoern Marcus , Sarigiannis Yiannis , Tarallo Andrea , Tytgat Jan , Undheim Eivind Andreas Baste , Utkin Yuri , Verdes Aida , Violette Aude , Zancolli Giulia 
Published: March 2021

Abstract
Venom research is a highly multidisciplinary field that involves multiple subfields of biology, informatics, pharmacology, medicine, and other areas. These different research facets are often technologically challenging and pursued by different teams lacking connection with each other. This lack of coordination hampers the full development of venom investigation and applications. The COST Action CA19144–European Venom Network was recently launched to promote synergistic interactions among different stakeholders and foster venom research at the European level.
Torix Rickettsia are widespread in arthropods and reflect a neglected symbiosis
Authors: Pilgrim Jack , Thongprem Panupong , Davison Helen R , Siozios Stefanos , Baylis Matthew , Zakharov Evgeny V , Ratnasingham Sujeevan , deWaard Jeremy R , Macadam Craig R , Smith M Alex , Hurst Gregory D D 
Published: March 2021

Abstract

Background
Rickettsia are intracellular bacteria best known as the causative agents of human and animal diseases. Although these medically important Rickettsia are often transmitted via haematophagous arthropods, other Rickettsia, such as those in the Torix group, appear to reside exclusively in invertebrates and protists with no secondary vertebrate host. Importantly, little is known about the diversity or host range of Torix group Rickettsia.

Results
This study describes the serendipitous discovery of Rickettsia amplicons in the Barcode of Life Data System (BOLD), a sequence database specifically designed for the curation of mitochondrial DNA barcodes. Of 184,585 barcode sequences analysed, Rickettsia is observed in ∼0.41% of barcode submissions and is more likely to be found than Wolbachia (0.17%). The Torix group of Rickettsia are shown to account for 95% of all unintended amplifications from the genus. A further targeted PCR screen of 1,612 individuals from 169 terrestrial and aquatic invertebrate species identified mostly Torix strains and supports the “aquatic hot spot” hypothesis for Torix infection. Furthermore, the analysis of 1,341 SRA deposits indicates that Torix infections represent a significant proportion of all Rickettsia symbioses found in arthropod genome projects.

Conclusions
This study supports a previous hypothesis that suggests that Torix Rickettsia are overrepresented in aquatic insects. In addition, multiple methods reveal further putative hot spots of Torix Rickettsia infection, including in phloem-feeding bugs, parasitoid wasps, spiders, and vectors of disease. The unknown host effects and transmission strategies of these endosymbionts make these newly discovered associations important to inform future directions of investigation involving the understudied Torix Rickettsia.
Imaging global mantle discontinuities: a test using full-waveforms and adjoint kernels
Authors: Koroni Maria , Trampert Jeannot 
Published: March 2021

SUMMARYWe present a novel approach for imaging global mantle discontinuities based on full-waveform inversion (FWI). Over the past decades, extensive research has been done on imaging mantle discontinuities at approximately 400 and 670 km depth. Accurate knowledge of their topography can put strong constraints on thermal and compositional variations and hence geodynamic modelling. So far, however, there is little consensus on their topography. We present an approach based on adjoint tomography, which has the advantage that Fréchet derivatives for discontinuities and measurements, to be inverted for, are fully consistent. Rather than working with real data, we focus on synthetic tests, where the answer is known in order to be able to evaluate the performance of the developed method. All calculations are based on the community code SPECFEM3D_GLOBE. We generate data in fixed 1-D or 3-D elastic background models of mantle velocity. Our ‘data’ to be inverted contain topography along the 400 and 670 km mantle discontinuities. To investigate the approach, we perform several tests: (i) In a situation where we know the elastic background model 1-D or 3-D, we recover the target topography fast and accurately; (ii) The exact misfit is not of great importance here, except in terms of convergence speed, similar to a different inverse algorithm and (iii) In a situation where the background model is not known, the convergence is markedly slower, but there is reasonable convergence towards the correct target model of discontinuity topography. It has to be noted that our synthetic test is idealized and in a real data situation, the convergence to and uncertainty of the inferred model is bound to be larger. However, the use of data consistent with Fréchet kernels seems to pay off and might improve our consensus on the nature of mantle discontinuities. Our workflow could be incorporated in future FWI mantle models to adequately infer boundary interface topography.
C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent nuclear accumulation of Staufen in neurons
Authors: Kim Eun Seon , Chung Chang Geon , Park Jeong Hyang , Ko Byung Su , Park Sung Soon , Kim Yoon Ha , Cha In Jun , Kim Jaekwang , Ha Chang Man , Kim Hyung-Jun , Lee Sung Bae 
Published: March 2021

Abstract
RNA-binding proteins (RBPs) play essential roles in diverse cellular processes through post-transcriptional regulation of RNAs. The subcellular localization of RBPs is thus under tight control, the breakdown of which is associated with aberrant cytoplasmic accumulation of nuclear RBPs such as TDP-43 and FUS, well-known pathological markers for amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD). Here, we report in Drosophila model for ALS/FTD that nuclear accumulation of a cytoplasmic RBP Staufen may be a new pathological feature. We found that in Drosophila C4da neurons expressing PR36, one of the arginine-rich dipeptide repeat proteins (DPRs), Staufen accumulated in the nucleus in Importin- and RNA-dependent manner. Notably, expressing Staufen with exogenous NLS—but not with mutated endogenous NLS—potentiated PR-induced dendritic defect, suggesting that nuclear-accumulated Staufen can enhance PR toxicity. PR36 expression increased Fibrillarin staining in the nucleolus, which was enhanced by heterozygous mutation of stau (stau+/−), a gene that codes Staufen. Furthermore, knockdown of fib, which codes Fibrillarin, exacerbated retinal degeneration mediated by PR toxicity, suggesting that increased amount of Fibrillarin by stau+/− is protective. stau+/− also reduced the amount of PR-induced nuclear-accumulated Staufen and mitigated retinal degeneration and rescued viability of flies expressing PR36. Taken together, our data show that nuclear accumulation of Staufen in neurons may be an important pathological feature contributing to the pathogenesis of ALS/FTD.
Work in progress report of a multicentre retrospective observational study to evaluate the association between the airflows and the intrapleural pressures digitally recorded after video-assisted lobectomy
Authors: Bertolaccini Luca , Viti Andrea , Bertoglio Pietro , Imperatori Andrea , Morelli Angelo , Zaraca Francesco , Spaggiari Lorenzo , Crisci Roberto ,   the In-Pression Trial Study Group, Bertolaccini Luca , Viti Andrea , Bertoglio Pietro , Imperatori Andrea , Morelli Angelo , Zaraca Francesco , Spaggiari Lorenzo , Crisci Roberto 
Published: March 2021

Abstract

OBJECTIVES
Digital chest drainage systems allow real-time and continuous monitoring and recording of air leak flow rate and intrapleural pressure (IPP) from the immediate postoperative period to the chest drainage removal. A multicentre retrospective observational analysis of consecutive patients undergoing pulmonary lobectomy for lung cancer was performed to evaluate the association between the airflow and IPP digitally recorded during the immediate postoperative period after video-assisted thoracic surgery (VATS) lobectomy for lung cancer. Here, we present a work in progress report.

METHODS
All patients treated with VATS lobectomies for lung cancer were included. Multiple airflow measurements and minimum and maximum IPP through the chest tubes were digitally monitored and recorded using microelectronic mechanical sensor technology. The PALs were defined as an air leak lasting &gt;5 days from the conclusion of the surgical procedure. The cessation of air leaks was defined as an airflow &lt;10 ml/min during 6 consecutive hours.

RESULTS
This analysis comprised 76 patients who underwent VATS lobectomy for lung cancer. Nineteen patients (25%) showed prolonged air leaks (PAL) (≥5 days). The operative time was higher in the PAL group (mean difference = 44 min) without a statistically significant difference. Before the 7th postoperative hours, there were no statistically significant differences in IPPs.

CONCLUSIONS
Patients with PAL showed less negative IPP in the first 24 postoperative hours. Therefore, the 7th—24th postoperative hours were critical in PAL prediction since the mechanism for PAL seems to develop after the 7th postoperative hour.
Design, modeling and parametric optimization of thermoelectric cooling systems for high power density electronic devices
Authors: Barrubeeah Mohammed , Rady Mohamed , Attar Alaa , Albatati Faisal , Abuhabaya Abdullah 
Published: March 2021

Abstract
The present article reports on the design, modeling and parametric optimization of a thermoelectric cooling system for electronics applications. An analytical model based on energy equilibrium is developed for cooling a microprocessor using a thermoelectric module with an air-cooled finned heat sink. The proposed analytical model is validated by experimental measurements and by comparison with detailed 3D numerical simulations. Estimation of effective material properties of the thermoelectric module using manufacturer-reported performance characteristics is found to reduce the uncertainty in the calculation of module input power as compared to experimental measurements. A parametric optimization of the thermoelectric module and heat sink is carried out to maximize the coefficient of performance (COP) and achieve the required cooling capacity of the microprocessor. The effectiveness of the proposed methodology is demonstrated for cooling current high power microprocessors. At a constant input current, the cooling capacity and COP of the thermoelectric cooling system increase with increasing thermoelectric module geometric ratio. Furthermore, at a constant geometric ratio, the cooling power increases with increasing input current to reach a maximum value and then decreases. The present study highlights the importance of designing and fabricating high-performance thermoelectric cooler modules with optimum parameters for cooling specific electronic components. The results indicate that the cooling capacity can be increased by ~70% using thermoelectric modules with optimized parameters as compared to using non-optimized commercially available thermoelectric modules.
Conforming and nonconforming VEMs for the fourth-order reaction–subdiffusion equation: a unified framework
Authors: Li Meng , Zhao Jikun , Huang Chengming , Chen Shaochun 
Published: March 2021

AbstractWe establish a unified framework to study the conforming and nonconforming virtual element methods (VEMs) for a class of time dependent fourth-order reaction–subdiffusion equations with the Caputo derivative. To resolve the intrinsic initial singularity we adopt the nonuniform Alikhanov formula in the temporal direction. In the spatial direction three types of VEMs, including conforming virtual element, $C^0$ nonconforming virtual element and fully nonconforming Morley-type virtual element, are constructed and analysed. In order to obtain the desired convergence results, the classical Ritz projection operator for the conforming virtual element space and two types of new Ritz projection operators for the nonconforming virtual element spaces are defined, respectively, and the projection errors are proved to be optimal. In the unified framework we derive a prior error estimate with optimal convergence order for the constructed fully discrete schemes. To reduce the computational cost and storage requirements, the sum-of-exponentials (SOE) technique combined with conforming and nonconforming VEMs (SOE-VEMs) are built. Finally, we present some numerical experiments to confirm the theoretical correctness and the effectiveness of the discrete schemes. The results in this work are fundamental and can be extended into more relevant models.
Tangential Weak Defectiveness and Generic Identifiability
Authors: Casarotti Alex , Mella Massimiliano 
Published: March 2021

Abstract
We investigate the uniqueness of decomposition of general tensors $T\in{\mathbb C}^{n_1+1}\otimes \cdots \otimes{\mathbb C}^{n_r+1}$ as a sum of tensors of rank $1$. This is done extending the theory developed in [ 28] to the framework of non-twd varieties. In this way, we are able to prove the non-generic identifiability of infinitely many partially symmetric tensors.