bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intervensi Dalam Pencegahan Cedera yang Tidak Disengaja pada Balita
Authors: Suryatmana Iin , Setiawan Agus 
Published: August 2021

Unintentional injury in children is a global problem that often occurs in all countries in the world. Various prevention efforts need to be done by all relevant stakeholders to reduce the number of unintentional injuries in children. The purpose of this study was to identify the effect of interventions on the prevention of unintentional injuries on children under 5 years (toddlers). A literature study with descriptive analysis was used in this study. Articles were obtained through an online database search on the ScienceDirect, Wiley, Sage, ProQuest, Google scholar databases published from 2015 to 2020. This study identified 48 articles and 9 articles met the inclusion criteria. The results of the study identified that in general all articles (n = 7) showed a positive effect on injury prevention in children, 1 article did not clearly illustrate its effect on prevention of child injury, 1 article had no effect on prevention of child injury. Future studies need to consider various risk factors that influence the effectiveness of an intervention in order to get positive results.
Keywords: injury prevention; toddlers; unintentional child injury

ABSTRAK

Cedera yang tidak disengaja pada anak merupakan masalah global yang bayak terjadi di seluruh negara di dunia. Berbagai upaya pencegahan perlu dilakukan oleh semua stakeholder terkait untuk menekan angka kejadian cedera yang tidak disengaja pada anak. Tujuan studi ini adalah megidentifikasi pengaruh intervensi terhadap pencegahan cedera yang tidak disengaja pada anak di bawah 5 tahun (balita). Metode studi literatur dengan analisis deskriptif digunakan dalam studi ini. Artikel diperoleh melalui penelusuran online database ScienceDirect, Wiley, Sage, ProQuest, Google scholar yang terbit dari 2015 hingga 2020. Studi ini mengidentifikasi 48 artikel serta 9 artikel memenuhi kriteria inklusi. Hasil studi mengidentfikasi bahwa secara umum semua artikel (n=7) menunjukkan dampak positif terhadap pencegahan cedera pada anak, 1 artikel tidak tergambar jelas pengaruhnya terhadap pencegahan cedera anak, 1 artikel tidak berpengaruh terhadap pencegahan cedera anak. Penelitian selanjutnya perlu mempertimbangakan berbagai faktor risiko yang mempengaruhi efektifitas suatu intervensi agar mendapatkan hasil yang positif.
Kata kunci: balita; cedera yang tidak disengaja pada anak; pencegahan cedera
Dukungan Sosial Keluarga dan Tingkat Kecemasan Penderita TB Paru di Puskesmas Kambaniru Kabupaten Sumba Timur
Authors: Namuwali Domianus , Hara Maria Kareri , E.S Gunawan Yosephina 
Published: August 2021

Background: Tuberculosis or TB was the main cause of death in infectious diseases. In 2017 there were 1.3 deaths due to TB. Globally, it was estimated that the incidence of TB disease was around 10.0 million and most prevalent in men around 5.8 million. Approximately 90% of TB patients were found in adults above 15 years old. In 2018, the number of TB sufferers in Kambaniru health center was 31 people. Objective: The purpose of this study was to identify the correlation of family social support towards the anxiety of TB patients in Kambaniru Health Center, East Sumba Regency. Methods: The research method used was a quantitative method with cross sectional design. The sampling was taken by using a total sampling technique with a sample size of 31 respondents. This research was conducted in Kambaniru Health Center from August to September 2019. Results: The results of this study found that the most respondents had moderate anxiety as many as 16 people (51.6%), the most family social support was good as many as 20 respondents (64.4%) and from the Spearman Correlation Test it was found that there was no significant correlation between family social support and the level of anxiety of TB patients in Kambaniru Health Center. Conclusion: There was no correlation between family social support and anxiety level of TB patients in Kambaniru Health Center.
Keywords: family social; support, anxiety level; TB patients

ABSTRAK

Latar belakang: PenyakitTB Paru merupakan penyebab utama kematian pada penyakit infeksi, Pada tahun 2017 terdapat 1,3 kematian akibat penyakit TB. Secara global diperkirakan insiden penyakit TB Paru sekitar 10,0 juta dan paling banyak ditemukan pada laki-laki sekitar 5,8 juta. sekitar 90% Penderita TB Paru ditemukan pada usia dewasa ≥ 15 tahun. Pada tahun 2018 jumlah penderita TB paru di Puskesmas Kambaniru sebanyak 31 orang. Tujuan: Tujuan dari penelitian untuk mengidentifikasi hubungan dukungan social keluarga terhadap kecemasan pada penderita TB paru di Puskesmas Kambaniru Kabupaten Sumba Timur. Metode: Metode penelitian yang digunakan kuantitatif dengan rancangan cross sectional. Pengambilan sampel dilakukan dengan teknik total sampling dengan ukuran sampel 31 responden. Penilitian ini dilaksanakan di Puskemas Kambaniru pada Bulan Agustus – September 2019. Hasil: Hasil dari penelitian ini didapatkan bahwa sebagian besar responden mengalami kecemasan sedang sebanyak 16 orang (51,6%), Dukungan sosial keluarga terbanyak adalah baik sebanyak 20 responden (64,4%) dan dari hasil Uji Korelasi Spearman didapatkan tidak ada hubungan yang signifikan dukungan social keluarga dengan tingkat kecemasan penderita TB Paru di Puskesmas Kambaniru. Kesimpulan: Tidak ada hubungan dukungan social keluarga dengan tingkat kecemasan penderita TB paru di Puskesmas Kambaniru.
Kata kunci: dukungan sosial keluarga; tingkat kecemasan; penderita TB
Manajemen Mitigasi Bencana Menggunakan Teknologi Balloon Tethered
Authors: Nirmalasari Nining , Sahar Junaiti 
Published: August 2021

Introduction: The occurrence of natural disasters in Indonesia from year to year continues to occur, with the progress of communication technology that is increasingly expected to be able to facilitate communication when a disaster occurs. Such as the use of balloon tethered technology that can function for disaster mitigation, with the use of balloon tethered that is tethered in areas that are at risk of disaster prone. Methods: The method used by the author was literature review. The database used by the author were Google Scholar, IEEE Xplore, GEOECO, EBSCOhost, Researchgate and the keywords were disaster mitigation, Tethered Balloon technology, Aerial Platform. Results: This tethered balloon technology consists of a combination of flying balloons, tethered, and payload, for the use of disaster mitigation and supports faster broadband communication networks to users before or during and after a disaster. The rescue team can work more effectively and efficiently with the help of this tethered balloon technology. Conclusion: Cross-sectoral collaboration involving various disciplines is needed for disaster mitigation management. The role of the government is very large for the availability of communication technology such as tethered balloons.
Keywords: disaster mitigation; tethered balloon; platform

ABSTRAK

Pendahuluan: Kejadian bencana alam di Indonesia dari tahun ke tahun terus terjadi, dengan adanya kemajuan teknologi komunikasi yang semakin berkembang diharapkan dapat memudahkan komunikasi saat terjadi bencana. Seperti pada penggunaan teknologi balon tethered yang dapat berfungsi untuk mitigasi bencana, dengan penggunaan balon tethered yang ditambatkan di daerah yang beresiko rawan bencana. Metode: Metode yang digunakan penulis adalah literature review. Database yang digunakan penulis adalah Google Scholar, IEEE Xplore, GEOECO, EBSCOhost, Researchgate dengan mitigasi bencana, tehnologi Tethered Balloon, Aerial Platform. Hasil: Teknologi balon tethered terdiri atas gabungan balon terbang, tethered, dan payload, untuk penggunaan mitigasi bencana dan mendukung jaringan komunikasi broadband yang lebih cepat kepada pengguna sebelum atau selama dan sesudah bencana. Tim penyelamat dapat bekerja lebih efektif dan efisien dengan bantuan teknologi balon tethered ini. Kesimpulan: kerjasama lintas sektoral yang melibatkan berbagai disiplin ilmu dibutuhkan untuk manajemen mitigasi bencana. Peranan pemerintah sangat besar untuk ketersediaan teknologi komunikasi seperti balon tethered ini.
Kata kunci: mitigasi bencana; tethered balloon; platform
An Investigation of Differences in Lower Extremity Biomechanics During Single-Leg Landing From Height Using Bionic Shoes and Normal Shoes
Authors: Xu Datao , Zhou Huiyu , Baker Julien S. , István Bíró , Gu Yaodong 
Published: August 2021

Bionic shoes utilizing an actual foot shape sole structure can alter lower limb’s biomechanics, which may help in the development of specific training or rehabilitation programs. The purpose of this study was to investigate the biomechanical differences in the lower limb during a single-leg landing task using bionic shoes (BS) and normal shoes (NS). Fifteen healthy male subjects participated in this study, sagittal, and frontal plane data were collected during the landing phase (drop landing from 35 cm platform). Our study showed that BS depicted a significantly greater minimum knee flexion angle at initial contact (p = 0.000), a significantly greater minimum (initial contact) hip flexion angle at initial contact (p = 0.009), a significantly smaller sagittal plane total energy dissipation (p = 0.028), a significantly smaller frontal plane total energy dissipation (p = 0.008), a significantly smaller lower limb total energy dissipation (p = 0.017) than NS during the landing phase. SPM analysis revealed that BS depicted a significantly smaller knee joint vertical reaction force during the 13.8–19.8% landing phase (p = 0.01), a significantly smaller anterior tibia shear force during the 14.2–17.5% landing phase (p = 0.024) than NS. BS appears to change lower limb kinematics at initial contact and then readjust the landing strategies for joint work and joint reaction force, thereby reducing the risk of lower limb skeletal muscle injury. BS have great potential for future development and application uses, which may help athletes to reduce lower limb injury risk.
Comparison of the Reductions in LDL-C and Non-HDL-C Induced by the Red Yeast Rice Extract Xuezhikang Between Fasting and Non-fasting States in Patients With Coronary Heart Disease
Authors: Zhu Li-Yuan , Wen Xing-Yu , Xiang Qun-Yan , Guo Li-Ling , Xu Jin , Zhao Shui-Ping , Liu Ling 
Published: August 2021

Background: Xuezhikang, an extract of red yeast rice, effectively lowers fasting blood lipid levels. However, the influence of Xuezhikang on the non-fasting levels of low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C) has not been explored in Chinese patients with coronary heart disease (CHD).Methods: Fifty CHD patients were enrolled and randomly divided into two groups (n = 25 each) to receive 1,200 mg/d of Xuezhikang or a placebo for 6 weeks as routine therapy. Blood lipids were repeatedly measured before and after 6 weeks of treatment at 0, 2, 4, and 6 h after a standard breakfast containing 800 kcal and 50 g of fat.Results: The serum LDL-C levels significantly decreased, from a fasting level of 3.88 mmol/L to non-fasting levels of 2.99, 2.83, and 3.23 mmol/L at 2, 4, and 6 h, respectively, after breakfast (P &lt; 0.05). The serum non-HDL-C level mildly increased from a fasting level of 4.29 mmol/L to non-fasting levels of 4.32, 4.38, and 4.34 mmol/L at 2, 4, and 6 h post-prandially, respectively, and the difference reached statistical significance only at 4 and 6 h after breakfast (P &lt; 0.05). After 6 weeks of Xuezhikang treatment, the patients had significantly lower fasting and non-fasting serum levels of LDL-C and non-HDL-C (P &lt; 0.05) than at pretreatment. The LDL-C levels were reduced by 27.8, 28.1, 26.2, and 25.3% at 0, 2, 4, and 6 h, respectively, and the non-HDL-C levels were reduced by 27.6, 28.7, 29.0, and 28.0% at 0, 2, 4, and 6 h, respectively, after breakfast. No significant difference was found in the percent reductions in the LDL-C and non-HDL-C levels among the four different time-points.Conclusions: Six weeks of Xuezhikang treatment significantly decreased LDL-C and non-HDL-C levels, with similar percent reductions in fasting and non-fasting states in CHD patients, indicating that the percent change in non-fasting LDL-C or non-HDL-C could replace that in the fasting state for evaluation the efficacy of cholesterol control in CHD patients who are unwilling or unable to fast.
Association Between Sleep Apnea and Valvular Heart Diseases
Authors: Pelaia Corrado , Armentaro Giuseppe , Miceli Sofia , Perticone Maria , Toscani Alfredo Francesco , Condoleo Valentino , Spinali Martina , Cassano Velia , Maio Raffaele , Caroleo Benedetto , Lombardo Nicola , Arturi Franco , Perticone Francesco , Sciacqua Angela 
Published: August 2021

Background: Although sleep respiratory disorders are known as a relevant source of cardiovascular risk, there is a substantial lack of trials aimed to evaluate the eventual occurrence of associations between sleep apnea (SA) and valvular heart diseases (VHD).Methods: We recruited 411 patients referring to our sleep disorder unit, among which 371 had SA. Ninety-three subjects with SA also suffered from VHD. Physical examination, echocardiography, nocturnal cardio-respiratory monitoring, and laboratory tests were performed in each patient. Patient subgroups were comparatively evaluated through cross-sectional analysis.Results: A statistically significant increase in the prevalence of VHD was detected in relation to high apnea hypopnea index (AHI) values (p = 0.011). Obstructive sleep apnea occurrence was higher in SA patients without VHD (p &lt; 0.0001). Conversely, central and mixed sleep apneas were more frequent among SA patients with VHD (p = 0.0003 and p = 0.002, respectively). We observed a direct correlation between AHI and BMI values (p &lt; 0.0001), as well as between AHI and serum uric acid levels (p &lt; 0.0001), high sensitivity C-reactive protein (p &lt; 0.0001), and indexed left ventricular end-diastolic volume (p &lt; 0.015), respectively. BMI and VHD resulted to be the main predictors of AHI values (p &lt; 0.0001).Conclusions: Our study suggests that a significant association can occur between SA and VHD. It is clinically relevant that when compared to SA patients without VHD, higher frequencies of central and mixed apneas were found in subjects with SA and VHD. Moreover, after elevated BMI, VHD represented the second predictor of AHI values.
Insights on the Formation of Nanoparticles Prepared by Magnetron Sputtering Onto Liquids: Gold Sputtered Onto Castor Oil as a Case Study
Authors: Sergievskaya Anastasiya , O’Reilly Amy , Alem Halima , De Winter Julien , Cornil David , Cornil Jérôme , Konstantinidis Stephanos 
Published: August 2021

Magnetron sputter deposition of metal targets over liquids allows producing colloidal solutions of small metal nanoparticles (NPs) without any additional reducing or stabilizing reagents. Despite that this synthetic approach is known for almost 15 years, the detailed mechanism of NP formation is still unclear. Detailed investigations must be carried out to better understand the growth mechanism and, ultimately, control the properties of the NPs. Here, the combination of the gold (Au) target and castor oil, a highly available green solvent, was chosen as a model system to investigate how different experimental parameters affect the growth of NPs. The effect of deposition time, applied sputter power, working gas pressure, and type of sputter plasma (direct current magnetron sputtering (DC-MS) vs. high-power impulse magnetron sputtering (HiPIMS)) on properties of Au NPs has been studied by UV-vis spectroscopy and transmission electron microscopy (TEM), and further supported by quantum-chemistry calculations and mass-spectrometry analysis. The mechanism of the Au NP formation includes the production of primary NPs and their subsequent aggregative growth limited by diffusion in the viscous castor oil medium. Final Au NPs have a narrow size distribution and a medium diameter of 2.4–3.2 nm when produced in DC-MS mode. The NP size can be increased up to 5.2 ± 0.8 nm by depositing in HiPIMS mode which, therefore, mimics energy and time-consuming post synthesis annealing.
Comparison of BRICS-TM Countries' Biosimilar Regulatory Frameworks With Australia, Canada and Switzerland: Benchmarking Best Practices
Authors: Rahalkar Hasumati , Sheppard Alan , Salek Sam 
Published: August 2021

Objectives: The aim of this study was to identify, compare and evaluate regulatory requirements for the biosimilar development and review processes in BRICS-TM (Brazil, Russia, India, China, South Africa, Turkey, Mexico) countries with mature regulatory systems of Australia, Canada, Singapore and Switzerland. It is hoped that this benchmark study provides an opportunity for BRICS-TM agencies to identify the key areas for improvement in their regulatory processes.Materials and Methods: A semi-quantitative questionnaire was developed covering the different criteria used in biosimilar development and registration process. Eleven regulatory agencies from BRICS-TM and ACSS (Australia, Canada, Switzerland and Singapore) countries were invited to take part in this study. Data processing and analysis was carried out using descriptive statistics for quantitative data and content analysis to generate themes for qualitative data.Results and Discussions: Nine of the 11 regulatory agencies recruited for the study completed the questionnaire. China and Singapore did not meet the deadline due to lack of resources. The organisational structure of BRICS-TM agencies revealed support from external assessors by most of these agencies in comparison with ACSS agencies. There was absence of reliance approach and participation in harmonisation activities across most BRICS-TM agencies. Despite alignment over biosimilarity, the mandate for in vivo non-clinical studies and additional local clinical studies in some of the BRICS-TM countries illustrates a lack of effective implementation of a step-wise approach. Adopting flexible regulatory standards in the sourcing of a RBP (Reference Biologic Product) by BRICS-TM similar to ACSS, will facilitate cost-effective development of biosimilar products.Conclusions: Comparative assessment of the biosimilar regulatory framework of BRICS-TM with ACSS agencies reveals the scope for enhancing efficiency of the regulatory approval process. To achieve this, BRICS-TM agencies should consider relying on reference agencies for alternative review mechanisms such as abridged or verification models, streamlined processes for providing scientific advice to developers and for waiving local clinical studies in-lieu of advanced scientific data.
Optical Parameters of Atomically Heterogeneous Systems Created by Plasma Based Low Energy Ion Beams: Wavelength Dependence and Effective Medium Model
Authors: Singh Krishn Pal , Bhattacharjee Sudeep 
Published: August 2021

The article presents the irradiation effects of low energy (∼0.5 keV) inert gaseous Argon ion beams on optical constants [real (n) and imaginary (k) parts of the refractive index], dielectric constants, skin depth, and optical conductivity of copper (Cu), silver (Ag), and aluminum (Al) metallic thin films (MTF). The optical constants of pristine MTF are obtained by employing the universal Kramers-Kronig (KK) technique. The reflectivity of pristine MTF measured using UV-VIS-NIR spectrophotometry is used as an input parameter in the KK technique to determine the optical constants as a function of energy [or wavelength (λ)] of incident light ranging between ∼1–4.96 eV (or 250–1,200 nm). For the irradiated MTF, the optical constants including the skin depth (δ = λ/2πk), optical conductivity (σ = nkc/λ), and dielectric constants (ϵ1 = n2 − k2 and ϵ2 = 2nk) with varying ion fluence have been investigated by implementing the Maxwell-Garnett (MG) approximation, used to determine the effective dielectric constants of a random mixture of two different mediums. Additionally, n and k obtained from MG approximation have been compared with those obtained using the pseudo- Brewster angle technique for four different laser wavelengths (405, 532, 632.8 and 670 nm) and are found to be in good agreement with each other. It is observed that the optical constants and optical conductivity of the MTF decrease with increase in ion beam fluence, while the skin depth increases. Besides the optical constants, the behavior of skin depth, dielectric constants, and optical conductivity of the irradiated MTF with varying fluence are discussed in this article.
Negative Effects of a Multimodal Inpatient CBASP Program: Rate of Occurrence and Their Impact on Treatment Outcome in Chronic and Treatment-Resistant Depression
Authors: Herzog Philipp , Häusler Sophia , Normann Claus , Brakemeier Eva-Lotta 
Published: August 2021

Background: A growing number of studies indicate that the Cognitive Behavioral Analysis System of Psychotherapy (CBASP) is effective in treating chronic depression. However, there is no systematic research into possible negative effects. Therefore, the objectives of the study were to investigate the rate of occurrence of negative effects of an inpatient CBASP program and their impact on treatment response.Methods: Patients with chronic depression and treatment resistance who completed the 12-week multimodal inpatient CBASP treatment program in an open trial (N = 52) retrospectively completed the Inventory for the Assessment of Negative Effects of Psychotherapy (INEP) during follow-up data collection. Severity of depressive symptoms was assessed self- and observer-rated at admission, discharge, and 6 months follow-up. Rates of occurrence of negative effects were calculated and binary logistic regression analyses were conducted to determine the relationship to treatment outcome.Results: The results indicate that 92.3% of patients reported having experienced at least one negative effect and 45.2% indicated dependence on their therapist. Stigmatization and financial concerns as well as intrapersonal changes were reported by about one-third. Only dependence on the therapist negatively impacted treatment outcome in both outcome measures.Conclusions: While almost all patients reported at least one negative effect of a multimodal inpatient CBASP treatment program, most of the reported negative effects appear to be benign. However, dependence on the therapist seems to have a negative impact on treatment outcome. If these results can be replicated in future large-scale, randomized controlled prospective studies, CBASP therapists should be aware of possible dependence and consciously address it during treatment.