bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antibody responses to the BBV152 vaccine in individuals previously infected with SARS-CoV-2
Authors: Kumar Nathella Pavan , Padmapriyadarsini C. , Uma Devi K. R. , Banurekha V. V. , Nancy Arul , Girish Kumar C. P. , Murhekar Manoj V. , Gupta Nivedita , Panda Samiran , Babu Subash , Bhargava Balram 
Published: September 2021

Background & objectives:
Vaccination against SARS-CoV-2 is a recommendation from the World Health Organization as the foremost preference in the current situation to control the COVID-19 pandemic. BBV152 is one of the approved vaccines against SARS-CoV-2 in India. In this study, we determined SARS-CoV-2–specific antibody levels at day 0 (baseline, before vaccination), day 28 ± 2 post-first dose (month 1) and day 56 ± 2 post-first dose (month 2) of BBV152 whole-virion–inactivated SARS-CoV-2 recipients, and compared the antibody responses of individuals with confirmed pre-vaccination SARS-CoV-2 infection to those individuals without prior evidence of infection.

Methods:
Blood samples were collected from 114 healthcare professionals and frontline workers who received BBV152 vaccine from February to May & June 2021. Prior infection with SARS-CoV-2 was determined at baseline. Serum samples were used to estimate SARS-CoV-2 nucleoprotein-specific IgG [IgG (N)], spike protein-specific IgG [IgG (S)] and neutralizing antibodies (NAb).

Results:
Participants with previous SARS-CoV-2 infection after a single vaccine dose elicited IgG (N) and IgG (S) antibody levels along with NAb binding inhibition responses levels were similar to infection-naïve vaccinated participants who had taken two doses of vaccine.

Interpretation & conclusions:
Our preliminary data suggested that a single dose of BBV152-induced humoral immunity in previously infected individuals was equivalent to two doses of the vaccine in infection-naïve individuals. However, these findings need to be confirmed with large sized cohort studies.
Cáncer Avanzado de Recto Bajo. Resección Anterior de Recto Ultrabaja Transesfintérica TaTME + Prostatectomía en bloque
Authors: Viola Malet Marcelo , Abreu Diego , Lapiedra Diego , Liz Alejandra , Cerchiari Emilia , Escuder Juan , Gayo Gonzalo , Lavega Alvaro , Gabito Isabel , Schreiber Andrés 
Published: September 2021

El cáncer de recto bajo requiere un enfoque multimodal multidisciplinario para su tratamiento. Hoy día la radioquimioterapia neoadyuvante es el tratamiento inicial, seguido de cirugía con intención curativa.
Presentamos un video de un caso clínico de un paciente con un cáncer de recto bajo al que realizamos una Resección Anterior de Recto Ultrabaja Transesfintérica TaTME + Prostatectomía en bloque.
MENORES EXTRANJEROS: DOCUMENTO OFICIAL EXTRANJERO CONTRA PRUEBAS MÉDICAS EN LA DOCTRINA ADMINISTRATIVA Y JUDICIAL CONTENCIOSO-ADMINISTRATIVA ESPAÑOLA
Authors: LAFONT NICUESA LUIS 
Published: September 2021

Con frecuencia se está planteando situaciones en que de un documento
oficial extranjero ¿normalmente un pasaporte¿ se deduce, atendiendo a
la fecha de nacimiento, una edad determinada de su titular y de las pruebas médicas
practicadas a esa misma persona resulta una edad distinta. El problema alcanza
su mayor intensidad cuando en un instrumento probatorio resulta ser mayor
y en otro menor. En tal caso, el estatuto jurídico-administrativo del extranjero
se modifica sustancialmente al poder ser expulsado administrativamente si se
trata de un mayor de edad. El objeto del presente trabajo es analizar las resoluciones
administrativas y judiciales que examinan la materia.
Sarri askotan gertatzen da atzerriko dokumentu ofizial batetik
¿gehienetan, pasaporte batetik¿, jaiotze-eguna kontuan hartuta, titularrak adin
jakina daukala uste izatea, eta gero azterketa medikuek erakustea pertsona horrek
beste adin bat duela. Arazoa intentsitate handienera iristen da baldin probarako
tresna batean adinez nagusia irteten bada eta bestean adinez txikia. Kasu horretan,
atzerritarraren estatutu juridiko-administratiboa asko aldatzen da, adinez nagusia
baldin bada gerta litekeelako administrazio bidetik herrialdetik kanpora bidaltzea.
Lan honen helburua da gai hori lantzen duten ebazpen administratiboak eta judizialak
aztertzea.
It happens very often that on the basis of a foreign official
document ¿normally a passport¿ in accordance with the date of birth therein,
a concrete age of its holder is deduced and the clinical tests to that same person
show a different age. The problem reaches at its utmost intensity when as a result
of a probative tool in one is older than in the other. If that is the case, the legal
administrative status for the foreigner is substantially modified because he or
she is older than 18 years old. The scope of this present work is to analyze the
administrative and judicial resolutions which study the topic.
LA MENTE DEL LEGISLADOR EN LOS PROGRAMAS DE LA ASIGNATURA DE EDUCACIÓN POLÍTICA EN LAS ESCUELAS ALEMANAS, EN LA LOE Y EN LA LEGISLACIÓN EDUCATIVA DE LA CAPV
Authors: ELÓSEGUI ICHASO MARÍA 
Published: September 2021

Este artículo trata de la legislación sobre los programas de Educación
política en Alemania, siguiendo el itinerario de la asignatura desde la intención
o la mente del legislador a la hora de diseñar unos contenidos legalmente
obligatorios hasta el control administrativo de los manuales, para continuar con
su puesta en práctica en el aula. El diseño de los contenidos concretos de la asignatura
son realizados por cada Land alemán. Se introducen algunas comparaciones
entre el modelo alemán con la mentalidad del legislador autonómico de la
CAPV a la hora del diseño de la educación en Derechos Humanos en su legislación
educativa, así como una comparación de la asignatura alemana de Politik con el
diseño de las asignaturas de Historia y de EpC, estudiando en este caso tanto la
LOE como la legislación de la CAPV.
Alemaniako hezkuntza-politikako programen gaineko legislazioari
buruzkoa da honako artikulu hau. Ikasgaiaren ibilbidea jarraituko dugu,
legegileak legeak derrigortutako eduki batzuk diseinatzen dituen unean buruan
duen asmotik hasi eta manualen kontrol administratibora arte; gero, ikasgai hori
gelan nola taxutzen den aztertuko dut. Ikasgaiaren eduki zehatzen diseinua Alemaniako
Lan bakoitzak egiten du bere kasa. Zenbait alderaketa ere egingo ditut,
eredu alemaniarra eta EAEko legegile autonomikoaren mentalitatea konparatzeko,
bakoitzaren hezkuntza-legediaren arabera Giza Eskubideen arloko hezkuntza nola
diseinatzen duten ikusteko. Politik ikasgai alemana ere alderatuko dut hemengo
Historia eta EpC ikasgaiarekin, HLO eta EAEko legedia aztertuz.
This article deals with the legislation of the programmes of the
subject «Political Education» in Germany by following the educational pathway
on the basis of the legislator¿s purpose and mind when establishing some
compulsory legal contents an as far as the administrative control of materials,
and finally with the introduction into the classroom. The design of the concrete
contents of the subject is established by each German Land. They are introduced
some comparisons between the German model and the autonomic legislator¿s
mind from the Basque Country when it comes to designing Education in Human
Rights in its educative legislation as well as a comparison between the German
subject Politik and the design of subjects as History and Education for Citizenship,
by studying in this case both the Organic Act on Education and the legislation of
the Autonomous Community of the Basque Country.
Development of a coupled simulation framework representing the lake and river continuum of mass and energy (TCHOIR v1.0)
Authors: Tokuda Daisuke , Kim Hyungjun , Yamazaki Dai , Oki Taikan 
Published: September 2021

Abstract. Terrestrial surface water temperature is a key variable affecting water
quality and energy balance, and thermodynamics and fluid dynamics are tightly
coupled in fluvial and lacustrine systems. Streamflow generally plays a role
in the horizontal redistribution of heat, and thermal exchange in lakes
predominantly occurs in a vertical direction. However, numerical models
simulate the water temperature for uncoupled rivers and lakes, and the
linkages between them on a global scale remain unclear. In this study, we
proposed an integrated modeling framework: Tightly Coupled framework for
Hydrology of Open water Interactions in River–lake network (TCHOIR, read as
“tee quire”). The objective is to simulate terrestrial fluvial and
thermodynamics as a continuum of mass and energy in solid and liquid phases
redistributed among rivers and lakes. TCHOIR uses high-resolution geographical
information harmonized over fluvial and lacustrine networks. The results have
been validated through comparison with in situ observations and
satellite-based data products, and the model sensitivity has been tested with
multiple meteorological forcing datasets. It was observed that the
“coupled” mode outperformed the “river-only” mode in terms of discharge
and temperature downstream of lakes; moreover, it was observed that seasonal and
interannual variation in lake water levels and temperature are also more
reliable in the “coupled” mode. The inclusion of lakes in the coupled model
resulted in an increase in river temperatures during winter at midlatitudes
and a decrease in temperatures during summer at high latitudes, which reflects
the role of lakes as a form of large heat storage. The river–lake coupling
framework presented herein provides a basis for further elucidating the role
of terrestrial surface water in Earth's energy cycle.
Enhanced diapycnal mixing with polarity-reversing internal solitary waves revealed by seismic reflection data
Authors: Gong Yi , Song Haibin , Zhao Zhongxiang , Guan Yongxian , Zhang Kun , Kuang Yunyan , Fan Wenhao 
Published: September 2021

Abstract. Shoaling internal solitary waves near the Dongsha Atoll in the South China
Sea dissipate their energy and enhance diapycnal mixing, which have an
important impact on the oceanic environment and primary productivity. The
enhanced diapycnal mixing is patchy and instantaneous. Evaluating its
spatiotemporal distribution requires comprehensive observation data.
Fortunately, seismic oceanography meets the requirements, thanks to its high
spatial resolution and large spatial coverage. In this paper, we studied
three internal solitary waves in reversing polarity near the Dongsha Atoll and calculated their spatial distribution of diapycnal diffusivity. Our
results show that the average diffusivities along three survey lines are 2 orders of magnitude larger than the open-ocean value. The average
diffusivity in internal solitary waves with reversing polarity is 3 times that of the non-polarity reversal region. The diapycnal diffusivity is higher at the front of one internal solitary wave and gradually decreases from shallow to deep water in the vertical direction. Our results also
indicate that (1) the enhanced diapycnal diffusivity is related to
reflection seismic events, (2) convective instability and shear instability may both contribute to the enhanced diapycnal mixing in the
polarity-reversing process, and (3) the difference between our results and Richardson-number-dependent turbulence parameterizations is about 2–3 orders of magnitude, but its vertical distribution is almost the same.
Exploring near-synonymous terms in legal language. A corpus-based, phraseological perspective
Authors: Gozdz-Roszkowski Stanislaw 
Published: September 2021

This paper aims to determine the extent to which a corpus-based, phraseological approach can be effectively applied to discriminate among near-synonymous, semantically-related terms which often prove troublesome when translating legal texts. Based on a substantial multi-genre corpus of American legal texts, this study examines the collocational patterns of four legal terms ‘breach’, ‘contravention’, ‘infringement’ and ‘violation’, first in the genre of contracts and then in the multi-genre context of the entire corpus. The findings highlight the area of overlap as well as specificity in the usage of these terms. While collocational constraints can be argued to play an important disambiguating role in the semantic and functional analysis of both source and target text items carried out by translators prior to the interlingual translation, this study emphasizes the applicability of the phraseological approach to English source texts.
How multilingual can a dubbed film be? Language combinations and national traditions as determining factors
Authors: Voellmer Elena , Zabalbeascoa Patrick 
Published: September 2021

This paper analyses the German and Spanish dubbed versionsof Inglourious Basterds (Bender & Tarantino, 2009), two different translations of the same source text. In dialogue with relevant theory, we discuss the question of the extent to which a translated text can be heterolingual and how certain dubbing practices may prevent translations from being as heterolingual as their source texts. Our case study has also enabled us to find possible evidence of norms with regard to the translation of heterolingual films in Spain and in Germany. Linguistic variation is an important feature of Inglourious Basterds and it is both interlingual (different languages) and intralingual (dialects, sociolects and idiolects). Each dubbed version has its own initial situation and it is particularly interesting to see how linguistic variation is dealt with in translation. We propose the concept of ‘represented nationalities’ (similar to Delabastita’s 2010 “supposedly spoken” or “represented” languages) in the Spanish dubbed version of the film. As a theoretical contribution, we suggest that ‘intertextual translation’ is a more accurate term for translations of heterolingual texts (including dubbed versions) than Jakobson’s (1959) “interlingual translation”.
How do interpreters become heroes? Narratives on Soviet/Russian military interpreters
Authors: Probirskaja Svetlana 
Published: September 2021

This article identifies narratives, or storylines, which represent Soviet/Russian wartime/military interpreters. The data include the autobiographical writings of interpreters, documentaries, media articles, scholarly articles, and websites. The examination of the data proceeds to some extent in accordance with the narrative typology provided by Mona Baker (2006), that is, from general to personal narratives, with the assumption that personal narratives are embedded in collective narratives. The positioning of wartime interpreters participating in the Great Patriotic War (1941–1945) is compared to that of military interpreters participating in the military operations of the Soviet Union in the 1970s and 1980s. A narrative reading of the data uncovers the storylines that portray wartime/military interpreters as quiet war heroes.
The Evaluation of Regional Spatial Plan for 2011-2031 Based on Land Use Changes Prediction Using Cellular Automata-Markov Model in Sleman
Authors: Hardini Linggar Esty , Noveria Ana 
Published: September 2021

In the past years, the development of Sleman Regency has been considered rapid as evidenced by the emergence of built up areas including expansion of the university areas, shopping malls, and housing. Along with the increase in the total population, university students and workers from other regions coming to this regency, the land use in Sleman Regency has started to shift. Land use changes need to be controlled by predicting land use using the CA-Markov model. CA-Markov modeling has dynamic properties that integrate the dimensions of space and time, where the occurrence of events is determined by events that directly precede them and can be used to predict the next event. The accuracy of the CA-Markov concept can be determined by validation and expressed in the Kappa coefficient value (≥ 0.70). This CA-Markov concept has been developed since the 1940s in the field of computers by Von Neumann and Ulam. In this concept it is assumed that pixels are the beginning of the mathematical concept. When a pixel changes, its new status is only affected by its old status and the neighbor status. This research was conducted to predict the land use in 2031 using the Cellular Automata-Makov model, evaluate the use of land in 2031 in relation to RTRW or city plan, and create a scenario of the direction for land use control in 2031 for disaster-prone areas. Based on the prediction of land use in Sleman Regency in 2031, Kappa coefficient was obtained at 0.7399, implying that the suitability of spatial area and distribution reached 73.99% which is considered good. The results of the prediction also showed that in 2031, the land use would be dominated by building area which was predicted to reach 43.53% out of the total area. The evaluation of land use prediction in 2031 based on RTRW method showed that as large as 40.137,39 ha land would be used according to the RTRW, while 17.411,00 ha would not be used accordingly. The improper use of land might be due to the shift in the use of 4.659,18 ha of rice fields into buildings.
What Are Good Muscle Endpoints for Translational Studies?
Authors: Rittweger Jörn 
Published: September 2021

What Are Good Muscle Endpoints for Translational Studies?

Jörn Rittweger()1,2

1Institute of Aerospace Medicine, German Aerospace Center, Cologne, Germany
2Department of Pediatrics and Adolescent Medicine, University of Cologne, Cologne, Germany

© The Author

Abstract
Muscles matter to our health because of their size, their involvement in energy metabolism and their relevance for locomotion. Adequate selection of good endpoints is crucial for successfully designing translational studies. At least eight different muscle functions matter to health, namely the mechanical functions of exerting force, velocity, power, elastic storage and braking power, the two metabolic functions of substrate uptake (e.g. carbohydrates, lipids and amino acids) and substrate provision (e.g. lactate and amino acids) and secretory functions. However, specific endpoint tests have been validated for muscle force and power only. Walking speed and grip strength demonstrate good predictive value for hard clinical endpoints, such as disability, loss of autonomy and death. Vertical jump power also has good ecological validity and construct validity, and it depicts excellent test-retest reliability, which is an important advantage with regard to the study of power. Assessment of muscle mass, e.g. by magnetic resonance imaging, dual energy X-ray absorptiometry or bioelectrical impedance, should be considered as an important secondary endpoint to enhance construct validity. Further secondary endpoints should be included wherever they are likely to enhance the plausibility of the study outcome and assessment of test-retest reliability at baseline is always recommended. Well-established methods exist for three relevant muscular endpoints, namely power, strength and muscle mass, and these endpoints lend themselves to utilization in clinical studies. However, such validated methods lack a number of additional muscle functions that are scientifically only emerging. This applies foremost to the metabolic function of muscles but also to its role in storage and dissipation of mechanical energy.
Exercise, Pharmaceutical Therapies and Type 2 Diabetes: Looking beyond Glycemic Control to Whole Body Health and Function
Authors: Yates Thomas , Henson Joseph , Sargeant Jack , King James A , Ahmad Ehtasham , Zaccardi Francesco , Davies Melanie J 
Published: September 2021

Exercise, Pharmaceutical Therapies and Type 2 Diabetes: Looking beyond Glycemic Control to Whole Body Health and Function

Thomas Yates()1,2, Joseph Henson1,2, Jack Sargeant1,2, James A King2,4, Ehtasham Ahmad1, Francesco Zaccardi1,3 and Melanie J Davies1,2

1Diabetes Research Center, University of Leicester, Leicester General Hospital, Leicester, LE5 4PW, UK
2NIHR Leicester Biomedical Research Center, University Hospitals of Leicester NHS Trust and University of Leicester, UK
3Leicester Real World Evidence Unit, Diabetes Research Center, University of Leicester, Leicester, UK
4National Center for Sport and Exercise Medicine, School of Sport, Exercise and Health Sciences, Loughborough University, UK

© The Authors

Abstract
Exercise is a powerful therapy for improving glycemic control and increasing cardiorespiratory fitness in adults with type 2 diabetes mellitus (T2DM). However, there is a dearth of evidence investigating interactions or synergies between exercise and most pharmaceutical therapies. This is important as exercise is rarely prescribed in isolation of other background medications used to manage T2DM. Therefore understanding which exercise and drug combinations optimize or blunt responses is crucial. This narrative review discusses advances in weight loss management in diabetes and highlights research opportunities and challenges for combining exercise therapies with newer generations of glucose-lowering therapies with weight loss effects, particularly glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT2is). We discuss the role of exercise in preserving lean mass and increasing physical function along with other potential areas of synergy. We conclude that until the evidence base investigating areas of interaction or synergy between exercise and other glucose-lowering or weight loss therapies is developed, exercise will remain a generic rather than a tailored therapy in the management of T2DM.
Hubungan Dukungan Suami Dengan Kunjungan Antenatal Care (Anc) Pada Ibu Hamil Di Kabupaten Tabanan
Authors: Friska Armynia Subratha Hesteria , Manik Kartiningsih Ni Wayan 
Published: September 2021

Latar Belakang dan tujuan: Kehamilan adalah suatu krisis maturitas yang dapat menimbulkan stres. Tingginya cakupan K1 dan K4 tentunya sangat didukung oleh peran keluarga, dukungan keluarga salah satunya adalah dukungan suami. Tujuan penelitian ini adalah untuk mengetahui apakah ada hubungan dukungan suami dengan kunjungan antenatal care (ANC) pada ibu hamil di Bidan Praktek Mandiri Ny.MD Desa Cau, Kecamatan Marga, Kabupaten Tabanan.
Metode: Desain penelitian ini adalah servei analitik dengan pendekatan cross-sectional. Penelitian dilakukan pada bulan Juli 2014. Teknik sampel yang digunakan adalah total sampling dengan jumlah sebanyak 50 orang. Teknik analisa data menggunakan chi square test.
Hasil: Hasil penelitian menunjukkan bahwa Sebagian besar responden di BPM”MD” Desa Cau Kecamatan Marga Kabupaten Tabanan kurang mendapatkan dukungan suami. Sebagian besar responden di BPM”MD” Desa Cau Kecamatan Marga Tabanan sesuai standar kunjungan ANC. Ada hubungan yang signifikan dukungan suami dengan kunjungan ANC pada ibu hamil di BPM” MD” Desa Cau Kecamatan Marga Tabanan.
Simpulan: Responden di BPM”MD” Desa Cau Kecamatan Marga Kabupaten Tabanan kurang mendapatkan dukungan suami sebanyak 26 responden (52%).