bluuebunny/crossref_metadata_2025_split huggingface dataset:
(Invited) Electrospun Carbon Nanofibers for Applications in Fuel Cells and Li-Metal Batteries
Authors: Kim MinJoong , Kang Hyeonmuk , Cho EunAe 
Published: July 2021

Carbon nanofibers (CNFs) have been widely utilized in energy conversion and storage devices owing to their excellent electrical conductivities, large surface areas, structural and chemical stabilities. In fuel cells and water electrolyzers, CNFs can be used as a durable support for precious metal nanoparticle catalysts and also as a catalyst itself by being incorporated with nitrogen and transition metals. For lithium (Li) metal anode of rechargeable batteries, CNFs can serve as a interlayer to suppress the formation of Li dendrites.
In this talk, CNFs prepared by electrospinning polyacrylonitrile (PAN) and carbonization are presented for applications in fuel cells and Li-metal batteries. For fuel cell applications, transition metal precursors were added to the electrospinning solution to form the active sites for the oxygen reduction reaction [1]. To make mesoporous CNFs, silica nanoparticles polyvinyl acetate were added to the electrospinning solution [2]. To enhance the Li-ion adsorption on CNFs, metal nanoparticles were added to the spinning solution [3].
[1] M. Kim, D.-H. Nam, H.-Y. Park, C. Kwon, K. Eom, S. Yoo, J. Jang, H.-J. Kim, E.A. Cho, H. Kwon, Journal of Materials Chemistry A, 3, 14284-14290 (2015)
[2] M. J. Kim, J. H. Lim, J. Bak, D. H. Song, S. K. Oh, E. A. Cho "Fe and N Codoped Mesoporous Carbon Nanofiber as a Nonprecious Metal Catalyst for Oxygen Reduction Reaction and a Durable Support for Pt Nanoparticles", ACS Sustainable Chem. Eng., 7(20), 17544-17552 (2019)
[3] H. Kang, MS Thesis, KAIST (2020)

Figure 1
Associations of Subtype and Isomeric Plasma Carotenoids with Prostate Cancer Risk in Low-Income African and European Americans
Authors: Lee Sang-Ah , Cai Qiuyin , Franke Adrian A. , Steinwandel Mark , Wu Jie , Wen Wanqing , Zheng Wei , Blot William J. , Shu Xiao-Ou 
Published: July 2021

Abstract

Background:
Various carotenoids in circulation, including isomers, may have different influences on cancer risk.

Methods:
We conducted a nested case–control study including 343 incident prostate cancer cases and 640 controls individually matched on age, race, study site, and time of blood collection. Carotenoids investigated were carotene, cryptoxanthin, lycopene, dihydrolycopene, lutein, anhydrolutein, and zeaxanthin, including α versus β configurations and cis versus trans isomers. General linear model and conditional logistic regression were applied to evaluate associations for prostate cancer risk, with adjustment for potential confounders. We conducted additional analyses with further stratification by race, multivitamin use, and smoking status.

Results:
Case–control differences were found in carotenoid subtype levels, although not all reached the multiple comparison adjusted threshold for significance. Plasma lycopene [ORT1 vs. T3 = 0.51; 95% confidence interval (CI), 0.29–0.87; Ptrend = 0.014], dihydrolycopene (ORT1 vs. T3 = 0.37; 95% CI, 0.18–0.74; Ptrend = 0.006), and cis-anhydrolutein (ORT1 vs. T3 = 0.57; 95% CI, 0.33–0.96; Ptrend = 0.037) were inversely, while β-trans-carotene (ORT1 vs. T3 = 2.13; 95% CI, 1.32–3.43; Ptrend = 0.002) and trans-lutein (ORT1 vs. T3, 1.86; 95% CI, 1.20–2.88; Ptrend = 0.006) were positively associated with prostate cancer risk. Stratified analyses showed inverse associations of lycopene, dihydrolycopene, and cis-anhydrolutein with prostate cancer risk in subjects without multivitamin use; lycopene and dihydrolycopene in African-Americans and current smokers; and dihydrolycopene in nonsmokers. Positive associations of β-trans-carotene and trans-lutein were observed in African-Americans, nonsmokers, and multivitamin users.

Conclusions:
The associations of carotenoids with risk of prostate cancer differed by carotenoid subtypes.

Impact:
Public health recommendations on carotenoid intakes for prostate cancer prevention should take subtypes and isomers into consideration.
Adherence to the World Cancer Research Fund/American Institute for Cancer Research Cancer Prevention Recommendations and Colorectal Cancer Survival
Authors: Song Rui , Petimar Joshua , Wang Molin , Tabung Fred K. , Song Mingyang , Liu Li , Lee Dong Hoon , Giovannucci Edward L. , Zhang Xuehong , Smith-Warner Stephanie A. 
Published: July 2021

Abstract

Background:
Patients with cancer are recommended to follow cancer prevention guidelines due to inadequate evidence for specific recommendations for cancer survivors.

Methods:
We examined whether diet and lifestyle scores measuring adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) cancer prevention guidelines were associated with colorectal cancer–specific and overall mortality among 1,491 patients with colorectal cancer in two prospective cohorts. Cox proportional hazards regression models were used to calculate the multivariable-adjusted HRs and 95% confidence intervals (CI).

Results:
During a median follow-up of 7.92 years, there were 641 deaths (179 colorectal cancer–specific deaths). Patients in the highest quartile of the post-diagnostic WCRF/AICR lifestyle score including diet, body mass index (BMI), and physical activity had a 24% lower risk (HR = 0.76, 95% CI: 0.49–1.18) of colorectal cancer–specific mortality and a 37% lower risk (HR = 0.63, 95% CI: 0.50–0.78) of overall mortality compared with the lowest quartile. When BMI was not included in the lifestyle score due to potential disease-related weight loss, stronger inverse associations were observed for both colorectal cancer–specific and overall mortality for the same comparison (colorectal cancer–specific: HR = 0.50, 95% CI: 0.32–0.79; overall: HR = 0.59, 95% CI: 0.47–0.75). The post-diagnostic WCRF/AICR diet score was not statistically significantly associated with either colorectal cancer–specific or overall mortality.

Conclusions:
Greater adherence to the WCRF/AICR cancer prevention recommendations was associated with improved survival in patients with colorectal cancer.

Impact:
This study provides support for patients with colorectal cancer to follow cancer prevention recommendations after diagnosis. Future studies on cancer survivors will continue to contribute to evidence-based diet and lifestyle recommendations for patients with cancer.
Characteristics and Outcomes of Over 300,000 Patients with COVID-19 and History of Cancer in the United States and Spain
Authors: Roel Elena , Pistillo Andrea , Recalde Martina , Sena Anthony G. , Fernández-Bertolín Sergio , Aragón Maria , Puente Diana , Ahmed Waheed-Ul-Rahman , Alghoul Heba , Alser Osaid , Alshammari Thamir M. , Areia Carlos , Blacketer Clair , Carter William , Casajust Paula , Culhane Aedin C. , Dawoud Dalia , DeFalco Frank , DuVall Scott L. , Falconer Thomas , Golozar Asieh , Gong Mengchun , Hester Laura , Hripcsak George , Tan Eng Hooi , Jeon Hokyun , Jonnagaddala Jitendra , Lai Lana Y.H. , Lynch Kristine E. , Matheny Michael E. , Morales Daniel R. , Natarajan Karthik , Nyberg Fredrik , Ostropolets Anna , Posada José D. , Prats-Uribe Albert , Reich Christian G. , Rivera Donna R. , Schilling Lisa M. , Soerjomataram Isabelle , Shah Karishma , Shah Nigam H. , Shen Yang , Spotniz Matthew , Subbian Vignesh , Suchard Marc A. , Trama Annalisa , Zhang Lin , Zhang Ying , Ryan Patrick B. , Prieto-Alhambra Daniel , Kostka Kristin , Duarte-Salles Talita 
Published: July 2021

Abstract

Background:
We described the demographics, cancer subtypes, comorbidities, and outcomes of patients with a history of cancer and coronavirus disease 2019 (COVID-19). Second, we compared patients hospitalized with COVID-19 to patients diagnosed with COVID-19 and patients hospitalized with influenza.

Methods:
We conducted a cohort study using eight routinely collected health care databases from Spain and the United States, standardized to the Observational Medical Outcome Partnership common data model. Three cohorts of patients with a history of cancer were included: (i) diagnosed with COVID-19, (ii) hospitalized with COVID-19, and (iii) hospitalized with influenza in 2017 to 2018. Patients were followed from index date to 30 days or death. We reported demographics, cancer subtypes, comorbidities, and 30-day outcomes.

Results:
We included 366,050 and 119,597 patients diagnosed and hospitalized with COVID-19, respectively. Prostate and breast cancers were the most frequent cancers (range: 5%–18% and 1%–14% in the diagnosed cohort, respectively). Hematologic malignancies were also frequent, with non-Hodgkin's lymphoma being among the five most common cancer subtypes in the diagnosed cohort. Overall, patients were aged above 65 years and had multiple comorbidities. Occurrence of death ranged from 2% to 14% and from 6% to 26% in the diagnosed and hospitalized COVID-19 cohorts, respectively. Patients hospitalized with influenza (n = 67,743) had a similar distribution of cancer subtypes, sex, age, and comorbidities but lower occurrence of adverse events.

Conclusions:
Patients with a history of cancer and COVID-19 had multiple comorbidities and a high occurrence of COVID-19-related events. Hematologic malignancies were frequent.

Impact:
This study provides epidemiologic characteristics that can inform clinical care and etiologic studies.
Inhibition of MET Signaling with Ficlatuzumab in Combination with Chemotherapy in Refractory AML: Clinical Outcomes and High-Dimensional Analysis
Authors: Wang Victoria E. , Blaser Bradley W. , Patel Ravi K. , Behbehani Gregory K. , Rao Arjun A. , Durbin-Johnson Blythe , Jiang Tommy , Logan Aaron C. , Settles Matthew , Mannis Gabriel N. , Olin Rebecca , Damon Lloyd E. , Martin Thomas G. , Sayre Peter H. , Gaensler Karin M. , McMahon Emma , Flanders Michael , Weinberg Vivian , Ye Chun J. , Carbone David P. , Munster Pamela N. , Fragiadakis Gabriela K. , McCormick Frank , Andreadis Charalambos 
Published: July 2021

AbstractAcute myeloid leukemia (AML) patients refractory to induction therapy or relapsed within 1 year have poor outcomes. Autocrine production of hepatocyte growth factor by myeloid blasts drives leukemogenesis in preclinical models. A phase Ib trial evaluated ficlatuzumab, a first-in-class anti-HGF antibody, in combination with cytarabine in this high-risk population. Dose-limiting toxicities were not observed, and 20 mg/kg was established as the recommended phase II dose. The most frequent treatment-related adverse event was febrile neutropenia. Among 17 evaluable patients, the overall response rate was 53%, all complete remissions. Phospho-proteomic mass cytometry showed potent on-target suppression of p-MET after ficlatuzumab treatment and that attenuation of p-S6 was associated with clinical response. Multiplexed single-cell RNA sequencing using prospectively acquired patient specimens identified IFN response genes as adverse predictive factors. The ficlatuzumab and cytarabine combination is well tolerated, with favorable efficacy. High-dimensional analyses at single-cell resolution represent promising approaches for identifying biomarkers of response and mechanisms of resistance in prospective clinical studies.Significance:This study demonstrates a favorable safety profile and promising clinical activity of ficlatuzumab and cytarabine in high-risk AML, thus supporting further investigation of this combination in a randomized trial. It also shows the utility of a novel application using multiplexed single-cell analyses to detect on-target activity and identify biomarkers of response.This article is highlighted in the In This Issue feature, p. 403
Desenhar e (D)escrever: integração de história da arte e pensamento social na América Latina (século XIX)
Authors: Ciacchi Andrea 
Published: July 2021

O trabalho apresenta uma proposta metodológica de abordagem da atuação e da produção de artistas visuais (pintores e fotógrafos; europeus e latino-americanos) que, tendo realizando viagens, curtas ou longas, ou se transferindo para países estrangeiros, dentro da América Latina, tenham produzido, além de obras inerentes aos seus campos artísticos (pinturas, desenhos, gravuras, fotografias etc.), também textos descritivos, narrativos e/ou analíticos (cartas, diários, relatos, relatórios, ensaios, livros, conferências, manifestos, artigos etc.), para comentar, analisar, ilustrar com palavras os cenários, os elementos e os aspectos das várias dimensões da alteridade (étnica, racial e social) da região com as quais tenham entrado em contato. O objetivo do trabalho é apresentar uma proposta de uma linha temática e metodológica capaz de superar a disciplinarização nos estudos voltados ao pensamento social e à produção intelectual sobre América Latina. Para exemplificar a proposta, será abordado o caso de Guido Boggiani.
Overnight Rostral Fluid Shifts Exacerbate Obstructive Sleep Apnea After Stroke
Authors: Brown Devin L. , Yadollahi Azadeh , He Kevin , Xu Yuliang , Piper Bryan , Case Erin , Chervin Ronald D. , Lisabeth Lynda D. 
Published: July 2021

Background and Purpose:
Overnight shifts of fluid from lower to upper compartments exacerbate obstructive sleep apnea (OSA) in some OSA populations. Given the high prevalence of OSA after stroke, decreased mobility and use of IV fluids among hospitalized patients with stroke, and improvement in OSA in the months after stroke, we hypothesized that overnight fluid shifts occur and are associated with OSA among patients with subacute ischemic stroke.

Methods:
Within a population-based project, we performed overnight sleep apnea tests (ApneaLink Plus) during ischemic stroke hospitalizations. Before sleep that evening, and the following morning before rising from bed, we assessed neck and calf circumference, and leg fluid volume (bioimpedance spectroscopy). The average per subject overnight change in the 3 fluid shift measurements was calculated and compared with zero. Linear regression was used to test the crude association between each of the 3 fluid shift measurements and the respiratory event index (REI).

Results:

Among the 292 participants, mean REI was 24 (SD=18). Within individuals, calf circumference decreased on average by 0.66 cm (SD=0.75 cm,
P
<0.001), leg fluid volume decreased by a mean of 135.6 mL (SD=132.8 mL,
P
<0.001), and neck circumference increased by 0.20 cm (SD=1.71 cm,
P
=0.07). In men, when the overnight change of calf circumference was negative, an interquartile range (0.8 cm) decrease in calf circumference overnight was significantly associated with a 25.1% increase in REI (
P
=0.02); the association was not significant in women. The relationship between overnight change in leg fluid volume and REI was U shaped.

Conclusions:
This population-based, multicenter, cross-sectional study showed that in hospitalized patients with ischemic stroke, nocturnal rostral fluid shifts occurred, and 2 of the 3 measures were associated with greater OSA severity. Interventions that limit overnight fluid shifts should be tested as potential treatments for OSA among patients with subacute ischemic stroke.
A Printed Primer of Kabbalistic Knowledge: Sha‘arei Orah in East-Central Europe
Authors: Stillman Avinoam J. 
Published: July 2021

Abstract
This article explores the printed editions of Joseph Gikatilla’s Sha‘arei Orah in the broader context of kabbalistic knowledge in early modern East-Central Europe. Following its first Italian editions, the book was reprinted several times. The Kraków 1600 edition with commentary by Matityah Delacrut presented Sha‘arei Orah as a kabbalistic lexicon and study aid. The Offenbach 1715 edition included additional notes that linked Sha‘arei Orah to the Safedian Kabbalah of Moses Cordovero and Isaac Luria. Finally, the several editions published in Żółkiew exemplify the diversification of Kabbalah in the contentious religious climate of eighteenth-century Eastern Europe. Each printing reflects a discrete historical context, yet Sha‘arei Orah was consistently seen as an introductory guide to Kabbalah. Threading together these unique moments reveals one trajectory of the history of Kabbalah, as printing brought esoteric texts to new generations of readers with new concerns and agendas.
D.T. Suzuki at the World Congress of Faiths in 1936
Authors: Moriya Tomoe 
Published: July 2021

Abstract
This paper examines the speeches that D.T. Suzuki presented at the World Congress of Faiths in London in 1936 and analyzes his interactions with Buddhists, sympathizers, and critics in the West during the interwar period. It will uncover how various reactions and historical contexts constructed Suzuki’s discourses, which prepared Suzuki for popularizing Zen in postwar Western countries. Compared to his early years and post-1949 lectures in the United States, as well as his English publications on Mahayana Buddhism, his half-year journey through Europe in 1936 is understudied. With limited access to primary sources in Japanese and English, previous studies tended to label him a “nationalist.” Instead, I analyze Suzuki’s discourses and other newly discovered primary sources from a historical perspective. Through this analysis, this paper will clarify Suzuki’s scheme to present Mahayana Buddhism, particularly Zen, to Westerners during the interwar period.
Zootaxa 5000: dates and frequencies of publications with notes on monographs and special collections
Authors: ZHANG ZHI-QIANG 
Published: July 2021

On the occasion of the 5000th volume of Zootaxa, I herein provide the publication dates, page numbers and frequencies of all volumes/issues published in Zootaxa in one publication. The growth and development of Zootaxa are divided into three periods. The First Period (Explosive Growth) covers the first four years (Zootaxa 1 to 1,000) when each paper was separately issued; 67 monographs were published during this period. The Second Period (Transformation) includes over seven years and a half from Zootaxa 1,001 to the last volume of 2012 (2,598 issues in total) when two or more papers were included in the same volume of 60 pages or more; 538 monographs of 60 pages or more and 16 special volumes (collections of papers) were separately issued as before. The Third Period (Sustainable Development) started from the first volume in 2013 when two or more issues were included in the same volume of 600 pages; 2,740 issues were published; 926 monographs and 29 special volumes were separately issued as before.
Clarifying the propagation dynamics from meteorological to hydrological drought induced by climate change and direct human activities
Authors: Li Ziyan , Huang Shengzhi , Zhou Shuai , Leng Guoyong , Liu Dengfeng , Huang Qiang , Wang Hao , Han Zhiming , Liang Hao 
Published: July 2021

AbstractAn understanding of the propagation process from meteorological to hydrological drought contributes to accurate prediction hydrological drought. However, the comprehensive influence of direct human activities involved in drought propagation is not well understood. In this study, an identification framework for drought propagation time was constructed to quantify the effects of direct human activities (i.e., reservoir storage, irrigation, industrial, domestic and agricultural water consumption) on drought propagation. Subsequently, the effects of meteorological and underlying surface factors on the drought propagation process were clarified based on random forest method, and the driving effect of teleconnection factors was investigated from top to bottom. The Wei River Basin (WRB), the largest tributary of the Yellow River Basin, was selected as the case study. Results disclosed that the propagation time from meteorological to hydrological drought was short in summer (approximately 2 months) and autumn (approximately 3 months), while long in spring (approximately 3–5 months) and winter (approximately 3–8 months), exhibiting noticeable spatial variability. In a changing environment, the propagation time generally showed a decreasing trend in spring and winter, while increasing propagation time was observed in summer and autumn. The dynamic drought propagation time of each season was all jointly controlled by the different extent variation of meteorological and underlying surface conditions, and the basic flow is all relatively significant throughout the period. Direct human activities had an effect on the seasonal dynamics of drought propagation, especially during the winter of the non-flood season, which alleviated the severity of winter hydrological drought to some extent, thus delaying the transmission of meteorological signals to hydrological systems. Sunspots, the dominant direct teleconnection driving force in the WRB, could indirectly affect the local precipitation and base flow in spring, autumn, and winter and interferes with the drought propagation process. This study sheds new insights into the attribution of drought propagation dynamics in a changing environment.
Horizontal energy flux of wind-driven intraseasonal waves in the tropical Atlantic by a unified diagnosis
Authors: Song Qingyang , Aiki Hidenori 
Published: July 2021

AbstractIntraseasonal waves in the tropical Atlantic Ocean have been found to carry prominent energy that affects interannual variability of zonal currents. This study investigates energy transfer and interaction of wind-driven intraseasonal waves using single-layer model experiments. Three sets of wind stress forcing at intraseasonal periods of around 30 days, 50 days and 80 days with a realistic horizontal distribution are employed separately to excite the second baroclinic mode in the tropical Atlantic. A unified scheme for calculating the energy flux, previously approximated and used for the diagnosis of annual Kelvin and Rossby waves, is utilized in the present study in its original form for intraseasonal waves. Zonal velocity anomalies by Kelvin waves dominate the 80-day scenario. Meridional velocity anomalies by Yanai waves dominate the 30-day scenario. In the 50-day scenario, the two waves have comparable magnitudes. The horizontal distribution of wave energy flux is revealed. In the 30-day and 50-day scenarios, a zonally alternating distribution of cross-equatorial wave energy flux is found. By checking an analytical solution excluding Kelvin waves, we confirm that the cross-equatorial flux is caused by the meridional transport of geopotential at the equator. This is attributed to the combination of Kelvin and Yanai waves and leads to the asymmetric distribution of wave energy in the central basin. Coastally-trapped Kelvin waves along the African coast are identified by along-shore energy flux. In the north, the bend of the Guinea coast leads the flux back to the equatorial basin. In the south, the Kelvin waves strengthened by local wind transfer the energy from the equatorial to Angolan regions.