bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retracted: Development of a Highly Sensitive Wearable Tactile Sensor on Fabric by Using Conductive Inks Based on Electrical Contact Resistance (ECR) Change Mechanism
Authors: Chen Wei‐Lin , Karmakar Rajat Subhra , Liao Ying‐Chih , Lu Yen‐Wen 
Published: June 2021

AbstractA wearable tactile device, based on the electrical contact resistance (ECR) between the two fabric substrates, is developed in this work for continuous health monitoring. Microscale pillar structures are formed over top and bottom fabric substrates by screen‐printing technique with conductive inks followed by the face‐to‐face assembly of top and bottom parts. The contact areas between the substrates increase after the application of an external force, resulting the increment of charge carrier conduction and reduction in ECR value. To enhance the sensitivity, the device is optimized with two different conductive inks (i.e., silver and graphene inks) to create pillar shaped microstructures resulting a higher sensitivity due to the variation in ECR. This wearable tactile sensor's practical applications also are investigated in monitoring human wrist pulses with wireless module and smartphone, showing its capability in faster response and high sensitivity for internet‐of‐thing and medical applications.
Seasonal Abundance and Size Structure of Sharks Taken in the Pelagic Longline Fishery off Northwestern Cuba
Authors: Ruiz-Abierno Alexei , Márquez-Farías J. Fernando , Rojas-Corzo Ariadna , Miller Valerie , Angulo-Valdés Jorge A. , Hueter Robert E. 
Published: June 2021

Abstract
The Straits of Florida comprise an important migratory route for apex predators moving among the Gulf of Mexico, Atlantic Ocean, and Caribbean Sea. Off Cuba’s northwestern coast, various gear types are used by Cuban fishers, including small-scale pelagic longlines. We report here the results of a 2011–2019 monitoring program for the longline fleet based in Cojímar, Cuba. This fleet comprises 134 small vessels targeting mostly swordfish (family Xiphiidae), billfishes (family Istiophoridae), tunas (family Scombridae), and sharks (class Chondrichthyes) within 20 km of Cuba’s coast. Most operations are nocturnal with 11–12-h sets comprising an average of 56 hooks on 6,643 m of mainline. Five orders, eight families, and 18 species of sharks were documented in this fishery. Two carcharhinids (Silky Shark Carcharhinus falciformis and Oceanic Whitetip Shark C. longimanus) and two lamnids (Longfin Mako Isurus paucus and Shortfin Mako I. oxyrinchus) were the most abundant shark species caught, with shark CPUE averaging 1.98 sharks/trip (SD = 0.938). Catch abundance showed seasonal differences, with Silky Sharks and Longfin Makos more common in winter and Oceanic Whitetip Sharks more common in summer and autumn. Bimodal size structure in some species suggests multiple life stages utilizing the area, while the predominance of young sharks in species including the Oceanic Whitetip Shark suggests the importance of the area as juvenile habitat, possibly as a pupping and/or nursery ground. This characterization of the Cuban longline fishery is an important step forward for Cuba’s National Plan of Action for Sharks and demonstrates the potential impacts that small-scale fisheries can have on vulnerable sharks.
Landscape of IDH1/2 mutations in Chinese patients with solid tumors: A pan‐cancer analysis
Authors: Shen Dong , Zhang Junling , Yuan Kai , Zhao Jing , Zhao Zhengyi , Cui Longgang , Zhang Yuzi , Wang Guoqiang , Cai Shangli , Bai Yuezong , Li Wei , Huang Xiang 
Published: June 2021

AbstractBackgroundIsocitrate dehydrogenase (IDH) is an enzyme family involved in cell aerobic metabolism of tricarboxylic acid cycle. However, the landscape of IDH mutations in pan‐cancer has not been fully characterized.MethodsTissue or blood samples were subjected to next‐generation sequencing (NGS) for detection the IDH mutation.ResultsA total of 28.868 patients from more than 20 solid tumor species were analyzed. A total of 374 cases (1.30%) with IDH mutations were identified. Among all the IDH mutations cases, 80 (21.4%) were biliary tract cancer (BTC), 80 (21.4%) were lung cancer, 57 (15.2%) were liver cancer, and 42 (11.2%) were colorectal cancer. The most common IDH variant were IDH1 and IDH2 which were discovered in 0.81% cases and 0.47% cases, respectively. However, there were significant differences in IDH1 and IDH2 mutation frequency among different tumor species (p = 0.0003). Of the patients with IDH1 mutations, about 53.0% of these mutations occur in codons 132. Codons 172 (25.4%) was high‐frequency mutation subtypes in IDH2 mutation. TP53, PBRM1, and BAP1 were the most significantly mutated genes in BTC which were different from others cancer. Moreover, TMB were significantly higher in lung cancer, colorectal cancer, and gastric cancer than BTC (p = 0.0164, p < 0.0001, p = 0.0067, respectively) and BTC patients with IDH mutation had lower TMB compared with wild‐type IDH.ConclusionSomatic IDH mutation was found in multiple solid tumors and IDH would be a driver gene in BTC.
Characterization and correction of cardiovascular motion artifacts in diffusion‐weighted imaging of the pancreas
Authors: Geng Ruiqi , Zhang Yuxin , Starekova Jitka , Rutkowski David R. , Estkowski Lloyd , Roldán‐Alzate Alejandro , Hernando Diego 
Published: June 2021

PurposeTo assess the effects of cardiovascular‐induced motion on conventional DWI of the pancreas and to evaluate motion‐robust DWI methods in a motion phantom and healthy volunteers.Methods3T DWI was acquired using standard monopolar and motion‐compensated gradient waveforms, including in an anatomically accurate pancreas phantom with controllable compressive motion and healthy volunteers (n = 8, 10). In volunteers, highly controlled single‐slice DWI using breath‐holding and cardiac gating and whole‐pancreas respiratory‐triggered DWI were acquired. For each acquisition, the ADC variability across volunteers, as well as ADC differences across parts of the pancreas were evaluated.ResultsIn motion phantom scans, conventional DWI led to biased ADC, whereas motion‐compensated waveforms produced consistent ADC. In the breath‐held, cardiac‐triggered study, conventional DWI led to heterogeneous DW signals and highly variable ADC across the pancreas, whereas motion‐compensated DWI avoided these artifacts. In the respiratory‐triggered study, conventional DWI produced heterogeneous ADC across the pancreas (head: 1756 ± 173 × 10−6 mm2/s; body: 1530 ± 338 × 10−6 mm2/s; tail: 1388 ± 267 × 10−6 mm2/s), with ADCs in the head significantly higher than in the tail (P < .05). Motion‐compensated ADC had lower variability across volunteers (head: 1277 ± 102 × 10−6 mm2/s; body: 1204 ± 169 × 10−6 mm2/s; tail: 1235 ± 178 × 10−6 mm2/s), with no significant difference (P ≥ .19) across the pancreas.ConclusionCardiovascular motion introduces artifacts and ADC bias in pancreas DWI, which are addressed by motion‐robust DWI.
Three‐dimensional ridge collapse mechanism for narrow soil slopes
Authors: Michalowski Radoslaw L. , Park Dowon 
Published: June 2021

AbstractThree‐dimensional analysis of stability is carried out for slopes with the failure mechanism confined to a narrow space. A curvilinear cone failure surface is modified by removing a slice from its central portion, to make the failure mechanism fit in the narrow space. The resulting surface is no longer smooth, and it is referred to as the ridge mechanism for a distinct ridge in the failure surface. The analysis of narrow slopes based on the ridge mechanism appears to yield lower stability factors than the mechanisms used in geotechnical engineering thus far. Kinematic limit analysis utilized in calculations provides an upper bound to the true stability factor solution, hence the newly proposed mechanism delivers a more accurate solution.
Clinical significance of interventional therapeutic bronchoscopy combined with bronchial arterial embolization in the treatment of hypervascular primary airway tumors in children
Authors: Yang Haiming , Yin Jie , Tang Xiaolei , Li Gan , Li Huimin , Zhao Shunying 
Published: June 2021

ABSTRACTImportancePediatric hypervascular primary airway tumors are progressive, fatal lesions with a low incidence, and the disease is often more serious than that in adults.ObjectiveTo evaluate the clinical efficacy and safety of interventional therapeutic bronchoscopy combined with conservative treatment and bronchial arterial embolization in children with primary airway tumors.MethodsWe retrospectively analyzed the clinical data of four pediatric patients with hypervascular primary airway tumor between 2017 and 2019 at Beijing Children’s Hospital.ResultsTwo patients were low‐grade bronchial mucoepidermoid carcinoma, one patient was pleomorphic adenoma, and one was bronchial leiomyoma. Interventional therapeutic bronchoscopy combined with bronchial arterial embolization was used for treatment (all four patients received general anesthesia). The tumors were safely resected in all patients via interventional bronchoscopy. There were no severe complications related to the procedures. All patients were followed up for 5–12 months, and one low‐grade bronchial mucoepidermoid carcinoma recurred.InterpretationInterventional therapeutic bronchoscopy combined with bronchial arterial embolization appears to be a safe and efficient therapeutic method associated with less trauma and fewer complications, including no serious adverse events, in children with hypervascular primary airway tumors without bronchus wall infiltration.
Clinical characteristics and post‐discharge follow‐up analyses of 10 infants with congenital tuberculosis: A retrospective observational study
Authors: Du Juan , Dong Shixiao , Jia Shengnan , Zhang Qiaoru , Hei Mingyan 
Published: June 2021

ABSTRACTImportanceCongenital tuberculosis (TB) is a rare, potentially fatal disease. There is currently a lack of detailed clinical information available regarding this disease.ObjectiveThis retrospective study investigated the clinical manifestations, treatment, and long‐term prognosis of congenital TB.MethodsPatients were treated in Beijing Children’s Hospital, Capital Medical University (Beijing, China) between 2009 and 2018. Their demographic data, maternal and family histories, symptoms and signs, treatment information, and follow‐up data were retrospectively collected using the hospital’s electronic information system.ResultsTen infants with congenital TB were enrolled. The mean gestational age was 36.6 ± 2.2 weeks and mean birth weight was 2517 ± 487 g. All 10 patients exhibited fever, nine patients (90%) had anemia, and six patients (60%) had extrauterine growth retardation. On chest computed tomography scans, all 10 patients presented multiple pulmonary nodules and four patients (40%) had mediastinal adenopathy. Nine out of ten (90%) completed the T‐spot test, and eight of them (8/9, 89%) were positive. Anti‐TB treatment was initiated upon diagnostic confirmation. All patients (100%) received combined treatment with isoniazid (INH) and rifampicin (RIF). Eight of 10 patients (80%) received combined treatment with INH, RIF, and pyrazinamide. The survival rate was 100%. One patient was lost to follow‐up and four patients are currently continuing treatment. Three of nine patients (33%) achieved normal developmental milestones at 6 months of age.InterpretationEarly diagnosis based on maternal history, typical imaging results, and timely treatment can improve outcomes in infants with congenital TB.
Association of vitamin A status with lung function in children and adolescents with cystic fibrosis
Authors: Loukou Ioanna , Moustaki Maria , Sardeli Olympia , Plyta Marina , Katsagoni Christina N. , Douros Konstantinos 
Published: June 2021

ABSTRACTImportanceVitamin A (or retinol) has considerable antioxidative and anti‐inflammatory attributes and it may have protective effects on the respiratory health of patients with cystic fibrosis (CF). This issue, however, remains controversial.ObjectiveThe purpose of the present study was to investigate the relationship between serum retinol levels (SRL) and force expiratory volume in 1 second (FEV1) in patients with CF.MethodsAll patients with pancreatic insufficiency attending the CF Department of “Agia Sofia” Children’s Hospital in Athens, Greece, aged 6 to 19 years during the 2012–2016 period, who could perform spirometry effectively, were included in the study. The impact of SRL on FEV1 was examined longitudinally and analyzed with generalized estimating equations.ResultsThe study included 231 patients and 851 SRL measurements were performed. In 25 (3.2%) cases the SRL were below the 5th percentile of reference distribution; none was above the 95th percentile. The analysis showed that SRL was positively correlated with the FEV1 (P < 0.001).InterpretationIn this sample of children and adolescents with CF, vitamin A deficiency was rare. Our results suggest a positive relationship between SRL and FEV1.
DCX and CRABP2 are candidate genes for differential diagnosis between pre‐chemotherapy embryonic and alveolar rhabdomyosarcoma in pediatric patients
Authors: Sun Nian , Yang Yeran , Wang Shengcai , Zhang Jie , Gui Jingang , Tai Jun , He Lejian , Xu Jiatong , Li Yanzhen , Zhang Xuexi , Liu Qiaoyin , Liu Zhiyong , Guo Yongli , Ni Xin 
Published: June 2021

ABSTRACTImportanceRhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. More than 90% of cases are classified as embryonic RMS (ERMS) or alveolar RMS (ARMS). ERMS has a worse prognosis than ARMS. Early differential diagnosis is of paramount importance for optimization of treatment.ObjectiveTo identify genes that are differentially expressed between ARMS and ERMS, which can be used for accurate rhabdomyosarcoma classification.MethodsThree Gene Expression Omnibus datasets composed of ARMS and ERMS samples were screened and 35 differentially expressed genes (DEGs) were identified. Receiver operating characteristic curve analysis and area under the curve analysis was performed for these 35 DEGs and seven candidate genes with the best differential expression scores between ARMS and ERMS were determined. The expression of these seven candidate genes was validated by immunohistochemical analysis of pre‐chemotherapy ARMS and ERMS specimens.ResultsThe levels of DCX and CRABP2 were confirmed to be remarkably different between paraffin‐embedded ARMS and ERMS tissues, while EGFR abundance was only marginally different between these two RMS subtypes.InterpretationDCX and CRABP2 are potential biomarkers for distinguishing ARMS from ERMS in pre‐chemotherapy pediatric patients.
Plasma exchange therapy for acute necrotizing encephalopathy of childhood
Authors: Li Kechun , Zhang Tao , Liu Gang , Jin Ping , Wang Yeqing , Wang Lijie , Xu Meixian , Liu Chunyi , Liu Yingchao , Zhou Tao , Xu Yan , Yang Ying , Fang Boliang , Yang Xin , Liu Chunfeng , Qian Suyun 
Published: June 2021

ABSTRACTImportanceAcute necrotizing encephalopathy (ANE) is a rare disease with high mortality. Plasma exchange (PLEX) has recently been reported to treat ANE of childhood (ANEC), but its efficacy is uncertain.ObjectiveThis study aimed to investigate the effectiveness of PLEX on ANEC.MethodsA retrospective study was conducted in four pediatric intensive care units from December 2014 to December 2020. All patients who were diagnosed with ANEC were included; however, these patients were excluded if their length of stay was less than 24 h. Participants were classified into PLEX and non‐PLEX groups.ResultsTwenty‐nine patients with ANEC were identified, 10 in the PLEX group and 19 in the non‐PLEX group. In the PLEX group, C‐reactive protein, procalcitonin, alanine aminotransferase, and aspartate aminotransaminase levels were significantly lower after 3 days of treatment than before treatment (13.1 vs. 8.0, P = 0.043; 9.8 vs. 1.5, P = 0.028; 133.4 vs. 31.9, P = 0.028; 282.4 vs. 50.5, P = 0.046, respectively). Nine patients (31.0%, 9/29) died at discharge, and a significantly difference was found between the PLEX group and non‐PLEX group [0 vs. 47.4% (9/19), P = 0.011]. The median follow‐up period was 27 months, and three patients were lost to follow‐up. Thirteen patients (50.0%, 13/26) died at the last follow‐up, comprising three (33.3%, 3/9) in the PLEX group and ten (58.8%, 10/17) in the non‐PLEX group, but there was no significant difference between the two groups (P = 0.411). Three patients (10.3%, 3/29) fully recovered.InterpretationPLEX may reduce serum C‐reactive protein and procalcitonin levels and improve liver function in the short term. PLEX may improve the prognosis of ANEC, and further studies are needed.
Distribution‐free double‐sampling precedence monitoring scheme to detect unknown shifts in the location parameter
Authors: Malela‐Majika Jean‐Claude , Shongwe Sandile Charles , Aslam Muhammad , Chong Zhi Lin , Rapoo Eeva Maria 
Published: June 2021

AbstractIn most applications, parametric monitoring schemes are used to monitor the majority of industrial and nonindustrial processes in order to improve the quality of the outputs or services. However, parametric monitoring schemes are known to underperform when the normality assumption is not met or when there is not enough information about the symmetry or asymmetry nature of the process underlying distribution. Hence, in this paper, a new nonparametric Phase II Shewhart‐type double‐sampling (DS) monitoring scheme based on the precedence statistic is proposed in order to efficiently monitor quality processes when the underlying process distribution departs from normality. The performance is investigated using the average run length (ARL), standard deviation of the run length (SDRL), expected ARL (EARL) and expected average number of observations to signal (EANOS), and the average sample sizes (ASS) metrics. The latter metrics are computed using Monte Carlo simulation and exact formulae. In general, it is shown that the new DS precedence scheme outperforms the existing basic Shewhart precedence scheme with and without supplementary runs rules in many situations. A real‐life illustrative example based on a filling process of milk bottles is provided to demonstrate the application and implementation of the new DS precedence monitoring scheme.
Study of atmospheric pressure chemical ionization of phthalates in air by ion mobility spectrometry/mass spectrometry
Authors: Moravský Ladislav , Michalczuk Bartosz , Fateh Borkhari Arian , Papp Peter , Sysoev Alexey A. , Matejčík Štefan 
Published: June 2021

RationalePhthalates are widely used in consumer products in the chemical industries. Due to their abundance in the milieu, their potentially harmful effect on the environment, human and animal health there is a need for sensitive and fast methods for their detection.MethodsPositive polarity Corona Discharge Atmospheric Pressure Chemical Ionization (CD‐APCI) in the air was applied for ionization of phthalates. The ionization method for the phthalates was studied by atmospheric pressure Ion Mobility Spectrometry (IMS) and hybrid IMS/orthogonal acceleration Time‐of‐Flight Mass spectrometry (IMS‐oaTOF‐MS).ResultsCD‐APCI IMS and MS spectra of selected phthalates (dimethyl phthalate, diethyl phthalate, diethyl isophthalate, diethyl terephthalate, dipropyl phthalate, diisopropyl phthalate, dibutyl phthalate, diisobutyl phthalate, and dibutyl terephthalate) were recorded. In the case of the ortho‐ and “iso”‐isomers exclusively the protonated molecular ions [M + H]+ were detected. In the case of the para‐ and meta‐isomers and regioisomers, APCI resulted in the appearance of hydrated protonated molecular ions [M + H]+·(H2O)0,1,2. The ion mobilities, collision cross‐sections of these ions in air, as well as the limits of detection (LODs) for the phthalate vapors, were determined. In the case of isomeric phthalates, we have demonstrated the potential of the IMS technique for their separation.ConclusionsThe results show that CD‐APCI in combination with IMS and IMS‐oaTOF‐MS is a suitable method for the fast and sensitive detection of phthalates with the potential to separate some isomers.
Voicing Derbarl Yerrigan as a feminist anti‐colonial methodology
Authors: Wintoneak Vanessa , Blaise Mindy 
Published: June 2021

AbstractThe paper voices Derbarl Yerrigan, a significant river in Western Australia, through three imperfect, non‐innocent, and necessary river‐child stories. These stories highlight the emergence of a feminist anti‐colonial methodology that is attentive to settler response‐abilities to Derbarl Yerrigan through situated, relational, active, and generative research methods. Voicing Derbarl Yerrigan influences the methodological practices used as part of an ongoing river‐child walking inquiry that is concerned with generating climate change pedagogies in response to the global climate crises and calls for new ways of thinking and producing knowledge. In particular, the authors found that voicing as a methodology includes listening and being responsive to Derbarl Yerrigan's invitations, paying attention to pastspresentsfutures, and forming attachments through naming. By telling lively settler river‐child stories, this paper shows how voicing Derbarl Yerrigan is vital to open new possibilities for education and has implications for settler‐colonial contexts, where the focus on learning shifts from learning about the world to learning to become with multispecies river worlds.
Using machine learning to revisit the diversification–performance relationship
Authors: Choi Jaeho , Menon Anoop , Tabakovic Haris 
Published: June 2021

AbstractResearch SummaryIn this article, we examine the relationship between corporate diversification and firm performance using a machine learning technique called natural language processing (NLP). By applying a widely used NLP technique called topic modeling to unstructured text from annual reports, we create a new, multidimensional measure that captures the degree of diversification of both multisegment and single‐segment firms. Additionally, we introduce a novel method to incorporate human judgments into the interpretation of machine‐learned patterns, which allows us to measure diversification across multiple dimensions, such as products and geographies. Finally, we illustrate how these new measures can generate novel insights into the relationship between the degree and type of diversification and firm performance, furthering our understanding of the diversification–performance relationship.Managerial SummaryAt some point, most firms face dilemmas about whether to diversify their business activities across industries or geographic markets—an important decision that invariably affects firm performance. Albeit very important, the direction of a relationship between diversification and firm performance is not always clear. Inconsistent results of previous studies are partially driven by inherent difficulties in reliably measuring diversification. This study introduces a novel methodology to address that problem: a machine learning‐based technique to quantify diversification from unstructured corporate annual report texts. An analysis of firm performance based on these novel diversification measures suggests that diversification, in contrast to earlier studies that find a diversification discount, is associated with higher firm value—a premium particularly pronounced for firms diversifying within a single industry.