bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Model for The Classification of The Ripeness Stage of Pomegranate Fruits In Orchards Using
Authors: Cuong Nguyen Ha Huy 
Published: August 2021

Abstract
In agriculture, a timely and accurate estimate of ripeness in the orchard improves the post-harvest process. Choosing fruits based on their maturity stages can reduce storage costs and increase market results. In addition, the estimation of the ripeness of the fruit based on the detection of input and output indicators has brought about practical effects in the harvesting process, as well as determining the amount of water needed for irrigation. pepper, the amount of fertilizer for the end of the season appropriate. In this paper, propose a technical solution for a model to detect persimmon green grapefruit fruit at agricultural farms, Vietnam. Aggregation model and transfer learning method are used. The proposed model contains two object detection sub models and the decision model is the pre-processed model, the transfer model and the corresponding aggregation model. Improving the YOLO algorithm is trained with more than one hundred object types, the total proposed processing is 500,000 images, from the COCO image data set used as a preprocessing model. Aggregation model and transfer learning method are also used as an initial step to train the model transferred by the transfer learning technique. Only images are used for transfer model training. Finally, the aggregation model with the techniques used to make decisions selects the best results from the pre-trained model and the transfer model. Using our proposed model, it has improved and reduced the time when analyzing the maximum number of training data sets and training time. The accuracy of model union is 98.20%. The test results of the classifier are proposed through a data set of 10000 images of each layer for sensitivity of 98.2%, specificity 97.2% with accuracy of 96.5% and 0, 98 in training for all grades.
The Comparison of Accelerated Corneal Crosslinking Treatment for Progressive Keratoconus in the Pediatric and Adult Age Groups: One-Year Results
Authors: Berhuni Mustafa , Ozturkmen Cem 
Published: August 2021

Abstract
Purpose: To investigate the short-term results of accelerated crosslinking (A-CXL) treatment for progressive keratoconus in the pediatric and adult age groups. Materials and methods: The records of the 62 eyes of 40 patients who had undergone the A-CXL procedure (9 mV/cm2, 10 min) for progressive keratoconus between January 2015 and January 2019 were evaluated retrospectively. The patients were divided into 2 groups as the pediatric group (aged 17 years or less) and the adult group (aged 18 years or more) for statistical analysis. Pre- and post- 12th month A-CXL best-corrected visual acuity (BCVA), maximum keratometry (Kmax), sim K1, sim K2, corneal thickness at the thinnest point (thCT), and corneal astigmatism (CA) values of the patient groups were recorded. Results: The 29 eyes of 16 patients were included in the pediatric group and the 33 eyes of 24 patients were included in the adult group. The mean age was 13.50±3.05 years in the pediatric group and 23.58±4.37 years in the adult group. A significant improvement in BCVA and a significant decrease in thCT values were present in both groups 12 months after the surgery compared to the preoperative period. A decrease was present in the Kmax, sim K1, sim K2 and CA values in the pediatric group, but was not statistically significant. The decrease in Kmax, sim K1 and sim K2 values compared to the preoperative period was significant in the adult group, but the decrease in CA values was not significant. When the two groups were compared at the end of 12 months, only the sim K1 value was significantly lower in the adult group, and there was no significant difference between the other measurements. Conclusions: Better visual acuity improvement, a higher flattening rate, and less progression occur after 12 months with A-CXL treatment for progressive keratoconus in the adult age group compared to the pediatric age group.
Intelligent Bearing Fault Diagnosis using Swarm Decomposition Method and New Hybrid Particle Swarm Optimization Algorithm
Authors: Chegini Saeed Nezamivand , Amini Pouriya , Ahmadi Bahman , Bagheri Ahmad , Amirmostofian Illia 
Published: August 2021

Abstract
The quality of information extracted from the vibration signals, and the accuracy of the bearing status detection depend on the methods used to process the signal and select the informative features. In this paper, a new hybrid approach is introduced in which the relatively new Swarm Decomposition (SWD) method and the optimized Compensation Distance Evaluation Technique (OCDET) are used to enhance the signal processing stage and to improve the optimal features selection process, respectively. Firstly, the vibration signals are decomposed into their Oscillatory Components (OCs) using the SWD. The feature matrix is constructed by computing the time-domain features for the OCs. The CDET method is consequently utilized to select the most sensitive features corresponding to the bearing status. On the other hand, The CDET approach contains a parameter called threshold which affects the number of the selected features. In this way, the hybrid optimization algorithm, which is a combination of the Particle Swarm Optimization (PSO) algorithm with the Sine-Cosine Algorithm (SCA) and the Levy flight distribution, has been used to select the optimal CDET threshold and improve the Support Vector Machine (SVM) classifier. The proposed technique ability is evaluated by vibration signals corresponding to different bearing defects and various speeds. The results indicate the capability of the proposed fault diagnosis method in identifying the very small-size defects under various bearing conditions. Finally, the presented method shows better performance in comparison with other well-known methods in the most of the case studies.
Long Term Evaluation of Posterior Corneal Surface Parameters after Accelerated Corneal Crosslinking with a Comparison with Uncross-Linked Keratoconic Eyes
Authors: KOSEKAHYA PINAR , Turkay Mine , Camgoz Esra Bahadır , Koc Mustafa , Toker Mustafa Ilker 
Published: August 2021

Abstract
Purpose: To evaluate the 36 months changes in posterior corneal surface parameters in keratoconic eyes after accelerated corneal cross-linking and to compare the data with uncross-linked progressive and non-progressive keratoconic eyes. Methods: Thirty five cross-linked, 30 uncross-linked progressive, and 30 uncross-linked non-progressive keratoconic eyes were included. Maximum keratometry (Kmax), thinnest pachymetry, minimum radius of curvature back (Rminback), asphericity back, posterior elevation and corneal densitometry, back corneal higher order aberrations (HOAs), back surface deviation (Db), final D, posterior radius of curvature (PRC) and ‘B’ unit values were recorded at baseline and at the 12, 24, 36 months follow-up. Data were analyzed with repeated measures ANOVA and paired t-tests.Results: Kmax and thinnest pachymetry were significantly changed in the cross-linked and progressive uncross-linked groups. Rminback, asphericity back, and HOAs did not change in either group. Total posterior corneal densitometry improved; posterior elevation, Db and B unit worsened in the cross-linked group and did not change in the uncross-linked groups. PRC and final D worsened in the cross-linked and progressive uncross-linked groups, and did not change in the non-progressive group. Conclusion: Despite a decreased Kmax, the posterior corneal surface parameters, posterior elevation values were determined to have significantly worsened in the cross-linked group and this increase was higher than in progressive uncross-linked eyes.
The Effects of Agricultural Financing on Agricultural Productivity in Nigeria
Authors: Danladi. Jonathan D. , Falaye Motunrayo Helen , OCHINKE NELLIEKEN ATTAH 
Published: August 2021

Abstract
The study “The Effects of Agricultural Finance on Agricultural Productivity in Nigeria” investigated the effect of agricultural financing, both public and private on the outputs of two main sectors of agriculture: crop production and livestock production. The objectives of the study are to examine the long and short run relationship of agricultural financing on crop production and livestock production, and to examine the causal relationship between agricultural finance and agricultural productivity. To achieve these objectives, the study employed two models, each using ARDL Test, Bounds Test, and Granger causality test using time series data from 1981 to 2019.Data were obtained from CBN and World Bank data bases. Dependent variables were Crop Production and Livestock Production respectively and independent variables were Public Finance, Commercial Bank Credit to Agriculture, Inflation Rate and Interest Rate. The model was tested using descriptive statistics to analyse the significance of the relationship between the dependent and independent variables. The results show that both public and private finance were positive but insignificant in the short run. In the long run, public finance remained insignificant whereas private finance was positive and significant. Thus, private financing is more effective at improving agricultural productivity than public finance. The study also revealed a negative long run relationship between interest rate and the outputs of crop and livestock production during the period. It is therefore recommended that the government encourages private investment in agricultural activity, and puts measures in place to curb corruption and embezzlement. Government should also ensure that credit facilities are provided to farmers at low interest rate to reduce it detrimental influences.
Human Urine-derived Stem Cells Improve Partial Bladder Outlet Obstruction in Rats: Preliminary Data and microRNA-mRNA Expression Profile
Authors: Tu Menjiang , Wang Rui , Zhu Pei , Wang Qingqing , Sun Bishao , Lu Keshi , Zhang Jiawei , Xie Weijie , Guo Huan , Li Shulin , Wu Yuqi , Wang Xiangwei 
Published: August 2021

Abstract
Background: Partial bladder outlet obstruction (pBOO), a common urological disease, often results in bladder tissue inflammation and remodeling. Human urine-derived stem cells (USCs) have demonstrated therapeutic benefits in various organ injury models. We used a rat model of pBOO to investigate the effect of USCs on bladder function and to explore the miRNA and gene expression profiles in bladder tissue using RNA sequencing.Methods: In total, 18 rats were randomly and evenly assigned to the following three groups: a sham surgery group, a pBOO without USC therapy group, and a pBOO with USC therapy group (subjected to treatment with USCs six times every other week). All rats were subjected to routine urodynamic monitoring. Detrusor muscle strips were analyzed and pathophysiology was assessed. Finally, altered miRNA and mRNA expression profiles of bladder tissue were examined using RNA sequencing and bioinformatics analysis technology.Results: After USC treatment, urodynamic monitoring revealed elevated bladder compliance and maximal voiding pressure, declined end filling pressure and voided volume, and improved detrusor muscle contractility and carbachol sensitivity in pBOO rats. Histology and TUNEL assay revealed reduced collagen deposition and muscle cell apoptosis in bladder tissue. The differential expression of eight miRNAs in pBOO rats was reversed by USC treatment. Bioinformatics analysis helped identify miR-142 and miR-9a as the two largest nodes of differentially expressed miRNAs in the miRNA‑gene interaction network in the USC-treated group. The Kyoto Encyclopedia of Genes and Genomes analysis revealed enrichment of multiple significant pathways, including those involved in necroptosis and cytokine-cytokine receptor interactions.Conclusions: This is the first study to reveal the protective effect of USCs on bladder function and bladder remodeling in pBOO rats. The miRNA and mRNA expression levels differed in the bladder of pBOO rats with and without USC treatment. Although the mechanism underlying these effects has not been fully elucidated, necroptosis and cytokine-cytokine receptor interaction-related pathways may be involved.
Concentrations of Neonicotinoids and their Characteristic Metabolites in Blood Samples from South China: Association with Liver Cancer
Authors: Zhang Hua , Zhang Renwen , Zeng Xujia , Wang Xiao , Wang Desheng , Jia Hongling , Xu Weiguo , Gao Yunfei 
Published: August 2021

Abstract
Neonicotinoid insecticides (NEOs) are commonly applied for pest control in China and around the world. They have potential toxicity to bees, birds, mammals, and even human being. However, limited studies have explored the associations between NEOs exposure and disease. In the present study, we detected six parent NEOs (p-NEOs), including acetamiprid, thiacloprid, dinotefuran, clothianidin, imidacloprid, and thiamethoxam, and five characteristic metabolites (m-NEOs), including 5-hydroxy-imidacloprid (5-OH-IMI), olefin-imidacloprid (Of-IMI), N-desmethyl-acetamiprid, 1-methyl-3-(tetrahydro-3-furylmethyl) guanidine and 1-methyl-3-(tetrahydro-3-furyl methyl) urea, in blood samples collected from healthy (n = 100) and liver cancer (n = 274) populations in South China. NEOs were frequently detected (61–94%) in blood samples, with median concentrations ranging from 0.19 ng/mL to 1.28 ng/mL and 0.20 ng/mL to 2.03 ng/mL for healthy and liver cancer populations, respectively. Of-IMI was the most abundant NEOs in healthy and liver cancer populations, accounting for 23.4% and 20.7%, respectively. Significant positive correlations among most m-NEOs concentrations were found, and associations between m-NEOs and their corresponding p-NEOs were positively correlated. These findings indicated that the sources of m-NEOs were both endogenous and exogeneous. Females had higher median concentrations of NEOs and their metabolites than males. Moreover, associations between the concentrations of p-NEOs and m-NEOs and liver cancer were found (odds ratio = 2.33–9.02, 95% confidence interval = 0.31–22.7, p < 0.05), indicating that human exposure to NEOs and their metabolites might increase the odds of liver cancer prevalence. This study is the first work to document 5-OH-IMI and DN in blood samples collected from South China.
Effect of NMDA Receptor Agonist and Antagonist on Spermatogonia Stem Cells Proliferation in 2- and 3- Dimensional Culture Systems
Authors: Noghani Amir Hessam Eskafi , Asadpour Reza , Saberivand Adel , Mazaheri Zohreh , Hamidian Gholamreza 
Published: August 2021

Abstract
The main purpose of this study was to investigate the effect of D-serine (DS) and Dizocilpine (MK-801or Mk) on the proliferation of SSCs in two-dimensional (2D) and three-dimensional (3D) culture systems. The SSCs of male NMRI mice were isolated by enzymatic digestion and cultured for two weeks. Then, the identity of SSCs was confirmed by anti-Plzf and anti-GFR-α1 antibodies via immunocytochemistry (ICC). The proliferation capacity of SSCs was evaluated by their culture on a layer of the decellularized testicular matrix (DTM) prepared from mouse testis, as well as two-dimensional (2D) with different mediums. After two weeks of the initiation of proliferation culture on 3D and 2D medium, the pre-meiotic at the mRNA and protein levels were evaluated via qRT-PCR and flow cytometry methods, respectively. The results showed that the proliferation rate of SSCs in three-dimensional culture with 50 mM glutamic acid and 20 mM D-serine was significantly different from other groups after 14 days treatment. mRNA expression levels of Plzf in 3D-cultures supplemented by 20 mM D-serine and 50 mM glutamic acid were considerably higher than the 3D control group (p<0.001). The flow cytometry analysis revealed that the amount of Plzf in the 2D-culture groups of SSCs with 20mM MK-801 was considerably lower compared to the 2D-culture control group (p<0.001). This study indicated that decellularized testicular matrix supplemented with D-serine and glutamic acid could be considered a promising vehicle to support cells and provide an appropriate niche for the proliferation of SSCs.
Health-related Quality of Life Among Cervical Cancer Patients at Kenyatta National Hospital
Authors: Ahamed Mehreen Shajahan , Degu Amsalu 
Published: August 2021

Abstract
Background: A previous systematic review showed that health-related quality of life (HRQoL) was adversely affected during treatment of cervical cancer, with a worsening global score. However, there was a lack of data in the study setting. Therefore, this study aimed to determine the HRQoL of cervical cancer patients at Kenyatta National Hospital.Methods: A cross-sectional design of the study was employed among cervical cancer patients. All eligible cervical cancer patients during the study period were included in the study. Hence, a consecutive sample of 103 cervical cancer patients was involved in the study. Following consent, study participants were interviewed using The European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire 30 (EORTC QLQ-30) and Cervical Cancer Module CX24 (EORTC QLQ-CX24). The clinical characteristics and treatment regimens were collected by reviewing the medical records. Interpretation and linear transformation of the raw score of health-related quality of life were conducted as per EORTC QLQ 30 and EORTC QLQ-CX24 Scoring Manual. The data were entered and analyzed using the Statistical Package for Social Sciences version 20.0 software. Frequency tables mean, percentage, and figures were used to represent the data. Univariate and multivariate binary logistic regression analysis was employed to investigate the associated factors of health-related quality of life. A p-value of ≤ 0.05 was considered statistically significant. Results: The mean age of the participant population was found to be 55.8 ± 5.6 years. Most of the study participants had stage III cervical cancer (56.3%) and without comorbidities (65%). The mean score of the global health status was 41.99. The physical functioning, cognitive functioning, and financial difficulties mean scores were 71.6, 73.3, and 93.5, respectively. Under the symptom scale, nausea and vomiting, pain, and appetite loss had mean scores of 70.1, 67.2, and 66.0, respectively. The overall quality of life data showed 69% of study participants had poor quality of life while 31% of study participants had good quality of life. Patients with early-stage disease (stage I and II) were 7.3 times (AOR = 7.3, 95% CI = 2.4 – 21.7, p = 0.000) more likely to have a good quality of life than patients with advanced-stage disease. Patients with no comorbidities were 3.1 times (COR = 3.1, 95% CI = 1.1 – 9.1, p = 0.037) more likely to have a good quality of life than patients with comorbidities.Conclusions: The overall health-related quality of life among cervical cancer patients was poor in the study setting. Advanced stage of disease and presence of comorbidities were the significant predictors of poor quality of life.
An aquifer is the control of magma eruption
Authors: Ding Yi , Wu Yunxia , Hou Zheng , Wu Wensheng , Tang Zongyuan 
Published: August 2021

Abstract
The location of a large group of maars in a basin of 200 km2 in Huitengxile, Inner Mongolia Autonomous Region of China, was probably the center of a magmatic plume in the past. The cross section of maars looks like saucers, with diameters ranging from the largest 900 to the smallest 10 m. Crashed rocks in strata exposed by the drill core and magnetic survey indicate explosions underground by insupportableness of steam accumulation from interaction of magma and water. In Huitengxile and other parts of Inner Mongolia, maars with the same shape and caprock age characteristics exist in an area of 30,000 km2, which indicates that they formed by substantial magmatic activity at the same time and in the same phreatic style. The aquifer layer in the crust constrained the eruption of the magma to overbear via phreatic shooting and releasing its energy. What has been happening at Yellowstone has similar phenomena to what had in Huitengxile and surroundings. The magmatic activities under Yellowstone may have been reined by an aquifer so that magma could not threaten the world.
Postoperative Blood Pressure and Heart Rate Alterations After Carotid Body Tumor Excision: A Retrospective Study of 108 Cases
Authors: Chen Si , Xu Jingjing , Gu Guangchao , Zhang Yuelun , Zhang Jiao , Zheng Yuehong , Huang Yuguang 
Published: August 2021

Abstract
Background
Arising from chemoreceptor cells, carotid body tumors (CBTs) are rare neoplasms associated with hemodynamics. Postoperative changes in blood pressure (BP) and heart rate (HR) are not completely understood.
Methods
This retrospective, observational, controlled study included all CBT patients from 2013 to 2018 in Peking Union Medical College Hospital. Postoperative changes in BP/HR within or between unilateral/bilateral/control groups were investigated. Perioperative details across Shamblin types were also assessed.
Results
This study included 108 patients (116 excised CBTs). The postoperative systolic BP and HR increased in both unilateral and bilateral CBT patients compared with the preoperative measures. Compared with control group, the postoperative systolic BP increased (difference in the alteration = 6.3, 95% CI 3.5 ~ 9.0, p < 0.001) in unilateral CBT patients; both systolic BP (difference in the alteration = 9.2, 95% CI 1.1 ~ 17.3, p = 0.027) and HR (difference in the alteration = 5.3, 95% CI 1.0 ~ 9.6, p = 0.016) increased in bilateral CBT patients. More CBT patients required extra antihypertensive therapy after surgery than controls (OR = 2.5, 95% CI 1.14 ~ 5.5, p = 0.024). Maximum tumor diameter, intraoperative vascular injury, continuous vasoactive agent requirement, total fluid volume/transfusion, estimated blood loss, operation duration, postoperative pathology, overall complications, and intensive care unit/hospital lengths of stay significantly varied among Shamblin types.
Conclusions
CBT excision may be associated with subtle postoperative hemodynamic changes. Perioperative management of CBT patients necessitates careful assessment, full preparation and close postoperative monitoring.
Diagnostic accuracy of pathogens in positive blood culture broths by Sepsityper Kit
Authors: Qi Le-Yao , Lin Min , Li Ya-Ping , Yu Zi-Yuan , Xie Tian-Ao , Guo xuguang 
Published: August 2021

Abstract
Background: Sepsis is a global medical problem and consistently the leading cause of death. Quick identification can help clinicians to determine the appropriate antibiotic treatment and reduce mortality. Sepsityper Kit is fast and easy-to-operate method. However, the studies on its performance is inconsistent. Thus, in other to fill the gap, we conducted data analysis to evaluate the effectiveness of the Sepsityper kit on pathogen identification. Methods: Relevant literature were searched in PubMed, Embase, Cochrane Library, and Web of Science. The correct identification rate of gram-positive bacteria, gram-negative bacteria, and fungi at the species and genus level were analyzed. Stata 12.0 was used to explore the publication bias of the included literature. Results: 30 articles were included. The diagnostic performance in gram-negative bacteria genus level was 96% (P = 0.000; I 2 = 80.9%), in gram-negative bacteria species level was 88% (P = 0.000; I 2 = 89.2%), in gram-positive bacteria genus level was 85% (P = 0.000; I 2 = 94.0%), in gram-positive bacteria species level was 65% (P = 0.000; I 2 = 89.2%), in genus level of fungi was 85% (P = 0.000; I 2 = 90.0%), and in the of species level of fungi was 59% (P = 0.000; I 2 = 97.0%), respectively. There is no publication bias in the study. Conclusions: The Sepsityper kit is a good method for the rapid diagnosis of all kinds of pathogenic microbes. Moreover, it is also very prominent in the identification of Gram-negative bacteria. Keywords : Sepsityper Kit, gram-negative bacteria, gram-positive bacteria, fungi, Sepsis