bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENINGKATAN KEMAMPUAN ARTIKULASI DAN PENGUASAAN KOSA KATA MELALUI METODE TUTOR SEBAYA PADA SISWA SDLB KELAS TUNARUNGU
Authors: Bajeri Darwina , Waspodo Muktiono , Herawati Herawati 
Published: January 2021

Penelitian ini adalah penelitian tindakan kelas (PTK). Subjek penelitian adalah peserta didik Sekolah Dasar dengan hambatan pendengaran di SLB Bina Mandiri Kota Bogor sebanyak 8 siswa. Subjek dalam penelitian ini memiliki hambatan pada pendengaran, hal ini berdampak rendahnya kemampuan artikulasi, dan rendahnya penguasaan kosakata peserta didik.Desain PTK menggunakan model Kemmis dan Taggart yang meliputi tahap perencanaan, pelaksanaan, pengamatan, dan refleksi. Teknik pengumpulan data menggunakan wawancara, observasi dan tes. Instrumen yang digunakan yaitu panduan wawancara, lembar observasi kemampuan artikulasi peserta didik serta tes penguasaan kosakata benda. Teknik analisis yang digunakan yaitu statistik deskripstif kuantitatif dan kualitatif.Hasil penelitian menunjukan adanya perbaikan pada proses pembelajaran Pengembangan Komunikasi Persepsi Bunyi dan Irama yang meningkatan kemampuan artikulasi dan penguasaan kosakata pada peserta didik melalui metode tutor sebaya. Perbaikan proses terlihat dari aktivitas peserta didik sebagai tutor bagi temannya yang kemampuannya lebih rendah, yaitu peserta didik menunjukan perhatian, ketertarikan dan respon yang baik dalam proses pembelajaran. Adapun hasil kemampuan artikulasi dan peguasaan kosakata peserta didik saat pra tindakan yaitu nilai terendah pada yaitu 22,5, siklus I menjadi 29 dan siklus II menjadi 55, nilai tertinggi pada pra-siklus yaitu 58, siklus I menjadi 68, dan siklus II menjadi 91, dengan nilai rata-rata pada pra-siklus yaitu 37,31 (sangat kurang), siklus I menjadi 50,12(kurang), dan siklus II menjadi 70,25 (baik).
Távoktatás másként
Authors: Benedek András 
Published: January 2021

Magyarországon a legnagyobb távoktatási hallgatói létszám a Budapesti Műszaki és Gazdaságtudományi Egyetem pedagógus szakirányú továbbképzéséhez kapcsolódik. Jelen írás érzékelteti, hogy a távoktatás iránt elkötelezetteket, a képzés fejlesztőit és szervezőit, milyen váratlanul értek azok a hírek, melyek március elején világszerte jelezték, hogy az oktatási rendszereknek a távolléti oktatásra történő gyors átállás kihívásával kell szembenézniük. Az elmúlt negyed században mintegy 27 ezer hallgató végzett programjainkon, melyeket korszerű oktatási keretrendszerben, kiváló szakmai konzulensekkel, innovatív oktatási formákban és módszerekkel valósítunk meg. Március 10-én az elsők között döntöttünk arról, hogy az online oktatásra történő átállás forgatókönyvét kidolgozzuk, májusban ennek eredményeként az elektronikus keretrendszer alkalmazásával sikeresen szigorlatoztak 44 tankörben 596-an. Június első két hetében pedig eredményesen záróvizsgáztak 375-en, teljesítve mindazon képzési követelményeknek, melyek az adott végzettségek - közoktatási vezető, mentortanár, mérés-értékelés szakértő, mestervezető - szakképesítés megszerzéséhez előírtak. In Hungary, it is the further training in pedagogical specialization at the Budapest University of Technology and Economics that has the highest number of students in distance education. This paper presents how unexpectedly those devoted to distance education, the developers and organizers of the training, were affected by the news that, at the beginning of March, indicated that the education systems had to face the challenges of rapid shift to remote learning all over the world. During the latest 25 years, about 27 thousand students have completed our educational programs that have been implemented in an up-to-date educational framework system, with excellent vocational consultants and using innovative educational forms and methods. On March 10th, we were one of the first to decide about elaborating the schedule of shifting over to online education, and as a result, in May, 596 persons in 44 learning groups successfully took their comprehensive examinations by applying the electronic framework system. During the first two weeks of June, 375 persons took their final exams, meeting all the training requirements that were prescribed to get the relevant qualifications (leader in public education, mentor teacher, expert of measuring and evaluation and master leader).
Osteogenic Differentiation of Renal Interstitial Fibroblasts Promoted by lncRNA MALAT1 May Partially Contribute to Randall’s Plaque Formation
Authors: Zhu Zewu , Huang Fang , Xia Weiping , Zeng Huimin , Gao Meng , Li Yongchao , Zeng Feng , He Cheng , Chen Jinbo , Chen Zhiyong , Li Yang , Cui Yu , Chen Hequn 
Published: January 2021

BackgroundThe current belief is that Randall’s plaques (RP) constitute a nidus for the formation of idiopathic calcium oxalate stones, but the upstream events in RP formation remain unclear. The present study aimed to investigate whether RP formation shares similarities with biomineralization and to illustrate the potential role played by the lncRNA MALAT1 in osteogenic differentiation of human renal interstitial fibroblasts (hRIFs).Materials and MethodsBiomineralization and MALAT1 expression were assessed in RP, and hRIFs were isolated and induced under osteogenic conditions for further experiments. The transcription initiation and termination sites in MALAT1 were identified by 5′ and 3′ RACE. RNA immunoprecipitation assays and luciferase assays were used to validate the interactions among MALAT1, Runx2 and miRNAs.ResultsUpregulated expression of osteogenic markers and MALAT1 was observed in RP and hRIFs induced with osteogenic medium. Biomineralization in RP and calcium phosphate (CaP) deposits in induced hRIFs were further verified by electron microscopy. Furthermore, overexpression of MALAT1 promoted the osteogenic phenotype of hRIFs, while treatment with a miR-320a-5p mimic and knockdown of Runx2 significantly suppressed the osteogenic phenotype. Further analysis showed that MALAT1 functioned as a competing endogenous RNA to sponge miR-320a-5p, leading to upregulation of Runx2 and thus promoting osteogenic differentiation of hRIFs.ConclusionEctopic calcification and MALAT1 partially contributed to the formation of RP, in which MALAT1 might promote Runx2 expression to regulate osteogenic differentiation of hRIFs by sponging miRNA-320a-5p. The current study sheds new light on the lncRNA-directed mechanism of RP formation via a process driven by osteogenic-like cells.
High-Resolution Spectral Sleep Analysis Reveals a Novel Association Between Slow Oscillations and Memory Retention in Elderly Adults
Authors: Kawai Makoto , Schneider Logan D. , Linkovski Omer , Jordan Josh T. , Karna Rosy , Pirog Sophia , Cotto Isabelle , Buck Casey , Giardino William J. , O'Hara Ruth 
Published: January 2021

Objective: In recognition of the mixed associations between traditionally scored slow wave sleep and memory, we sought to explore the relationships between slow wave sleep, electroencephalographic (EEG) power spectra during sleep and overnight verbal memory retention in older adults.Design, Setting, Participants, and Measurements: Participants were 101 adults without dementia (52% female, mean age 70.3 years). Delayed verbal memory was first tested in the evening prior to overnight polysomnography (PSG). The following morning, subjects were asked to recall as many items as possible from the same List (overnight memory retention; OMR). Partial correlation analyses examined the associations of delayed verbal memory and OMR with slow wave sleep (SWS) and two physiologic EEG slow wave activity (SWA) power spectral bands (0.5–1 Hz slow oscillations vs. 1–4 Hz delta activity).Results: In subjects displaying SWS, SWS was associated with enhanced delayed verbal memory, but not with OMR. Interestingly, among participants that did not show SWS, OMR was significantly associated with a higher slow oscillation relative power, during NREM sleep in the first ultradian cycle, with medium effect size.Conclusions: These findings suggest a complex relationship between SWS and memory and illustrate that even in the absence of scorable SWS, older adults demonstrate substantial slow wave activity. Further, these slow oscillations (0.5–1 Hz), in the first ultradian cycle, are positively associated with OMR, but only in those without SWS. Our findings raise the possibility that precise features of slow wave activity play key roles in maintaining memory function in healthy aging. Further, our results underscore that conventional methods of sleep evaluation may not be sufficiently sensitive to detect associations between SWA and memory in older adults.
Paclitaxel Coated Balloon vs. Bare Metal Stent for Endovascular Treatment of Symptomatic Vertebral Artery Origin Stenosis Patients: Protocol for a Randomized Controlled Trial
Authors: Wang Yabing , Ma Yan , Gao Peng , Chen Yanfei , Yang Bin , Feng Yao , Jiao Liqun 
Published: January 2021

Background: Stenting treatment for refractory symptomatic patients with vertebral artery origin stenosis (VAOS) is safe; however, there is a high rate of in-stent restenosis. Although drug-eluting stents can reduce the incidence of restenosis to some extent, there is still a risk caused by stent fracture. Drug-coated balloon (DCB) has been proven to reduce the rate of restenosis in peripheral and coronary artery disease. DCB can prevent inflammation caused by extraneous material stimulation and allow the subsequent treatment that is characteristic of “leave nothing behind.” The purpose of this trial is to compare the efficacy and safety of DCB and bare metal stent (BMS) in the treatment of VAOS.Method/Design: This trial is a 1:1 randomized, controlled, multicenter, non-inferiority trial that compares the DCB to BMS in terms of angiographically assessed target lesion binary restenosis (≥50%) at 12 months in endovascular treatment of symptomatic patients with VAOS.Discussion: A total of 180 patients with symptomatic VAOS who match the trial eligibility criteria will be randomized 1:1 to treatment with DCB (n = 90) or BMS (n = 90). An angiographic core laboratory-adjudicated target lesion binary restenosis (≥50%) at 12 months of follow-up was selected as primary efficacy endpoint to assess the DCB treatment effect. A clinical events committee will assess the safety endpoints of all-cause death, target vessel related transient ischemic attack and ischemic or hemorrhagic stroke events. A data safety monitoring board will periodically review safety data for subject safety, the study conduct, and progress. In this trial, randomization is only allowed after successful pre-dilatation. We anticipate that this trial will provide rigorous data to clarify whether DCBs are beneficial in patients with symptomatic VAOS.Clinical Trial Registration:www.ClinicalTrials.gov, identifier: NCT03910166.
Plaque Wall Distribution Pattern of the Atherosclerotic Middle Cerebral Artery Associates With the Circle of Willis Completeness
Authors: Li Jia , Zheng Lu , Yang Wen-Jie , Sze-To Cheuk-Yin , Leung Thomas Wai-Hong , Chen Xiang-Yan 
Published: January 2021

Objective: Investigating the relevance of the incomplete circle of Willis (COW) to the plaque wall distribution in the atherosclerotic middle cerebral arteries (MCAs) through utilizing high-resolution magnetic resonance imaging (HR-MRI), and its potential clinical impact.Methods: This hospital-based study enrolled consecutive adult patients with acute ischemic stroke or transient ischemic attack, who received a 3.0T Achieva MR system scanning. The COW completeness was evaluated on MR angiography imaging, including anterior (A) and posterior (P)-COW sections. The MCA plaque wall distribution was assessed on HR-MRI. The occurrence of perforator infarction was detected on diffusion-weighted imaging.Results: Among 87 patients (mean age = 62.39 ± 11.64 years old) with atherosclerotic plaques in the MCA M1 segments, the incomplete COW types were more prevalent than the complete COW type (incomplete P-COW, 83.9%; incomplete A-COW, 36.8%; complete COW, 8.1%). The incomplete A-COW had more inferior but fewer ventral plaques of MCA atherosclerosis than the complete A-COW, while the incomplete P-COW had fewer inferior MCA plaques than the complete P-COW. Moreover, symptomatic MCA plaques causing perforator infarctions were more likely to locate on the superior wall.Conclusion: Our findings suggested that the COW completeness could influence the vessel wall distribution of the MCA plaques, among which the superior plaques of symptomatic MCA atherosclerosis was associated with branch occlusive disease.
Correlation Between Cerebral Venous Oxygen Level and Cognitive Status in Patients With Alzheimer’s Disease Using Quantitative Susceptibility Mapping
Authors: Liu YangYingQiu , Dong JunYi , Song QingWei , Zhang Nan , Wang WeiWei , Gao BingBing , Tian ShiYun , Dong ChunBo , Liang ZhanHua , Xie LiZhi , Miao YanWei 
Published: January 2021

PurposeTo quantitatively assess the blood oxygen levels of the cerebral vein using quantitative susceptibility mapping (QSM), and to analyze the correlation between magnetic susceptibility value (MSV) and clinical laboratory indicators/cognitive scores in patients with Alzheimer’s disease (AD).Materials and MethodsFifty-nine patients (21 males and 38 females) with clinically confirmed AD (AD group) and 22 control subjects (12 males, 10 females; CON group) were recruited. Clinical data and laboratory examination indexes were collected. All patients underwent Mini-mental State Examination, Montreal Cognitive Assessment, Clock Drawing Task, and Activity of Daily Living Scale test, as well as a routine MRI and enhanced gradient echo T2 star weighted angiography (ESWAN).ResultsHigher cerebral venous MSV was observed in AD group compared to CON group, significant differences were observed for bilateral thalamus veins and left dentate nucleus veins. The MSV of bilateral thalamus veins, bilateral internal cerebral veins, and bilateral dentate nucleus veins had significant negative correlation with Mini-mental State Examination score; the MSV of bilateral thalamus veins, bilateral dentate nucleus veins, right septal vein had a significant negative correlation with Montreal Cognitive Assessment scores; a significant negative correlation between the MSV of bilateral thalamus veins, left dentate nucleus vein, right septal vein and the Clock Drawing Task score; the MSV of bilateral thalamus veins, left dentate nucleus vein had a significant negative correlation with Activity of Daily Living Scale score. The MSV of left dentate nucleus vein was positively correlated with the course of the disease, the MSV of bilateral septal vein were positively correlated with the total cholesterol, and the MSV of left septal vein had a positive correlation with LDL.ConclusionDecreasing cerebral venous oxygen level in AD patients may affect cognitive status, and associated with the deterioration of the disease in AD patients.
Correlation Between Local Air Temperature and the COVID-19 Pandemic in Hubei, China
Authors: Hu Cheng-yi , Xiao Lu-shan , Zhu Hong-bo , Zhu Hong , Liu Li 
Published: January 2021

Objective: To clarify the correlation between temperature and the COVID-19 pandemic in Hubei.Methods: We collected daily newly confirmed COVID-19 cases and daily temperature for six cities in Hubei Province, assessed their correlations, and established regression models.Results: For temperatures ranging from −3.9 to 16.5°C, daily newly confirmed cases were positively correlated with the maximum temperature ~0–4 days prior or the minimum temperature ~11–14 days prior to the diagnosis in almost all selected cities. An increase in the maximum temperature 4 days prior by 1°C was associated with an increase in the daily newly confirmed cases (~129) in Wuhan. The influence of temperature on the daily newly confirmed cases in Wuhan was much more significant than in other cities.Conclusion: Government departments in areas where temperatures range between −3.9 and 16.5°C and rise gradually must take more active measures to address the COVID-19 pandemic.
MUSZYNA ZDRÓJ - 10 YEARS OF SPATIAL CHANGES IN THE TOWN AND IN THE SPA
Authors: Karol Wójcikowski Wojciech 
Published: January 2021

The aim of the article is to present activities in Muszyna Zdrój, located in the region of southern Poland spa resorts. In Poland there are 45 spa resorts (mostly small towns and villages) half of them were developed in the southern part of Poland and many of them are interesting examples of the transformations of the urban public space in the spa resorts. Almost all those settlements are locate in the outstanding natural environment including landscapes, climate and above all in the water, confirm a number of studies and a long tradition of conducting treatment advances in medicinal uses of many diseases.
After a period of stagnation caused by ownership transformations in health resorts associated with the privatization and the reprivatisation of property nationalized after the Second World War. As well as long-term negligence in the period of system change in Poland after 1989.
The activities carried out during last 10 years in Muszyna Zdrój like in the other health resorts located in the south of Poland focused to improve the quality of public spaces in these towns. Muszyna Zdrój is one of the most effective in attracting financial resources from European funds for all designed activities example.
Muszyna Zdrój is a small historical town with developed in the beginning of XX century spa resort. The main advantages of the spa were climate, values of the landscape and sources of mineral waters. The spa resort is separate by the River Poprad from the town and develop separately. After few years of dynamic spatial changes in Muszyna Zdrój, the town and the spa resort become revitalized. Now Muszyna Zdrój is one of the good example of recent spatial changes in the health resorts of the whole of southern Poland spas.
The main revitalization activities in the health resort consisted in creating a modern place for outside events, walking areas, place when everyone can drink the mineral water from the source and rest in different and attractive parks or spend time in outside mineral pools. New paths along the Poprad River and parks, designed and implemented in the spa part of the resort serves both residents, visitors and numerous tourists visiting the town and the spa.
Activities undertaken in Muszyna Zdrój serve not only to improve the attractiveness of the town by improving the quality of public spaces for the comfort of visitors and tourists, but also for the sake of residents as well as natural resources of mineral resources thanks to which the spa towns have been functioning for centuries.
High-contrast fluorescence polarization microscopy through stimulated emission
Authors: Rehman Khalil Ur , Das Subir , Kao Fu-Jen 
Published: January 2021

Abstract
In this work, we demonstrate the contrast enhancement through polarization-resolved pump-probe microscopy, implemented by measuring the spontaneous fluorescence loss induced by stimulated emission. The pump-probe measurement is compared with the conventional fluorescence polarization microscopy. The anisotropy values thus obtained are 0.11 and 0.01, respectively. The contrast improvement is attributed to the multiphoton mechanism in sharpening the point-spread function and the polarization resolving. In addition, the pump-probe technique promises higher temporal resolution in lifetime measurements than time-correlated single-photon counting, enabling more precise determination of the fluorescent molecules’ rotational diffusion time constant, which is often in the sub-nanosecond regime.
Mobility improvement of 4H-SiC (0001) MOSFETs by a three-step process of H2 etching, SiO2 deposition, and interface nitridation
Authors: Tachiki Keita , Kaneko Mitsuaki , Kimoto Tsunenobu 
Published: January 2021

Abstract
4H-SiC(0001) metal-oxide-semiconductor field-effect transistors (MOSFETs) and MOS capacitors were fabricated by the following procedures: H2 etching, SiO2 deposition, and nitridation, and their electrical characteristics were evaluated. Substantially low interface state densities (4–6 × 1010 cm−2 eV−1) and high channel mobilities (80–85 cm2 V−1 s−1) were achieved by N2 annealing or NO annealing after H2 etching and SiO2 deposition. The threshold voltage of the MOSFETs fabricated with N2 annealing was shifted negatively when the oxide was formed by deposition. On the other hand, normally-off operation and high channel mobility were compatible for the MOSFETs fabricated with NO annealing.
Estructuración del centro de gestión ambiental urbana desde un enfoque de sustentabilidad en el barrio San Benito en Bogotá Colombia. Primer paso estado del arte
Authors: Ariza Ruiz Efrén Danilo 
Published: January 2021

El presente artículo de revisión bibliográfica pretende construir un estado del arte, que permita dotar de sustento teórico y metodológico una actuación local en el Barrio San Benito de Bogotá en la localidad de Tunjuelito, protegiendo los recursos hídricos, regulando de manera coherente el uso del suelo, reduciendo la contaminación en el aire, a través de la estructuración y puesta en marcha del CENTRO DE GESTIÓN AMBIENTAL URBANA EN EL BARRIO SAN BENITO DESDE UN ENFOQUE DE SUSTENTABILIDAD URBANA.
درجة تطبيق مفهوم مدارس التعلم الذكي في مدارس محافظة سلفيت الحكومية ومعوقات ذلك من وجهة نظر معلميها
Authors: محمد شلش د. باسم 
Published: January 2021

هدفت الدراسة إلى معرفة درجة تطبيق مفهوم مدارس التعلم الذكي في مدارس محافظة سلفيت الحكومية, ومعوقات ذلك من وجهة نظر معلميها، كما هدفت إلى الكشف عن الفروق في درجة تطبيق مفهوم مدارس التعلم الذكي التي تعزى إلى متغيرات (الجنس، والتخصص)، تكونت عينة الدراسة من (78) معلماً ومعلمة، وأعد الباحث إستبانةً مكونهً من خمس مجالات تخص إدارة المدرسة والإمكانات، والإدارة الصفية، والتقويم أو المعوقات، مكونة من (53) فقرة. وللإجابة عن أسئلة الدراسة وفرضياتها استخدم الباحث المنهج الوصفي، وقد دلت نتائج الدراسة على أن درجة تطبيق مفهوم المدرسة الذكية كان متوسطاً، كما بينت النتائج أن لا فروق في درجة تطبيق مفهوم مدارس التعلم الذكي تعزى إلى متغير الجنس، في حين ظهرت فروق في مجالات إدارة المدرسة , والإمكانات, والمعوقات لصالح الإناث. ونبهت التوصيات الى ضهورها تطوير البنى التحتية اللازمة لتطبيق فكرة المدارس الذكية, وضرورة إشراك المجتمع المحلي في تطبيق هذا المفهوم.
Baba Taheer Hemdany And Pantheism In His Double Distiches
Authors: Mahmoud Dr. Salar Aziz 
Published: January 2021

This research, which is prepared under the title Baba TaheerHemdany and pantheism in his double distiches is a literary & philosophical annalistically research. The study also explains his personality which is full of discussion and till now there are many problems to know his personality. One part of the study consists a strong relation between the poet and (Yarsan) religion which is beliefs in Transmigration of souls and effectuation of zeradushtra, Christian and Jewish. In the other hand there is minuteness by Iranian and Kurdish critics about his pout and his ethnic. At the end of thesis a number of conclusions are drawn which have pointed out by the researcher. the research ends with a list of the Bibliography that have been utilized in its preparation.