bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kinga Cecylia Stasiak (1981-2019)
Authors: Misztal-Konecka Joanna 
Published: August 2021

Artykuł stanowi wspomnienie i prezentację życia i dorobku śp. dr Kingi Sta­siak (1981–2019), przedwcześnie zmarłej znakomitej badaczki prawa między­narodowego publicznego. Ukazuje jej drogę zawodową, związaną z Katolickim Uniwersytetem Lubelskim Jana Pawła II, rozwój zainteresowań badawczych oraz zaangażowanie na rozmaitych polach aktywności naukowej, dydaktycznej i oso­bistej. Zwraca uwagę, że dorobek naukowy K. Stasiak poza monografią Trybunały umiędzynarodowione w systemie międzynarodowego sądownictwa karnego (Lublin 2012) obejmuje czternaście artykułów naukowych opublikowanych w czasopismach naukowych i pracach zbiorowych, pięć tłumaczeń tekstów źródłowych oraz trzy drobne wypowiedzi naukowe, jak też liczne hasła encyklopedyczne.
Artykuł przedstawia główne pola badawczych dociekań K. Stasiak, poczynając od umiędzynarodowionych trybunałów karnych, zakresu ich kompetencji, przebie­gu postępowania oraz znaczenia na arenie międzynarodowej. Jako kolejne obszary badań wskazuje warunki dopuszczalności interwencji humanitarnej, międzynaro­dowe prawo karne, ze szczególnym uwzględnieniem norm prawa międzynarodo­wego określających materialnoprawne i proceduralne aspekty odpowiedzialności za zbrodnie wojenne, przeciwko pokojowi i przeciwko ludzkości, zagadnienia we­wnętrznego systemu sprawiedliwości Organizacji Narodów Zjednoczonych, praw człowieka. Podkreśla wysoką kulturę słowa i sposób posługiwania się językiem prawniczym oraz odpowiedzialność za formułowane tezy, udowadniane zarówno przy okazji mniejszych, jak i bardziej rozbudowanych opracowań.
Artykuł akcentuje nadzwyczajne zaangażowanie dydaktyczne dr K. Stasiak, szeroką aktywność konferencyjną i translatorską oraz ofiarną służbę na rzecz ma­cierzystej Uczelni. Nie zapomniano o tym, że była wyjątkowo ciepłą, pracowitą, obowiązkową i wszechstronną osobą, a każdy, kto spotkał ją na swojej drodze, może potwierdzić, że zawsze była chętna do pomocy, podchodziła z szacunkiem i życzliwością do ludzi.
The effect of vitamin D deficiency state on oxidized low-density lipoprotein alteration in patients with type 2 diabetes
Authors: Salehi Salome Sadat , Karimpour Sahar , Rabizadeh Soghra , Esteghamati Alireza , Rajab Armin , Salehi Sousan Sadat , Nakhjavani Manouchehr , Mirmiranpour Hossein 
Published: August 2021

Introduction: The aim of this study was to compare oxidized low-density lipoprotein (oxLDL) and blood glucose in very low and low levels of vitamin D.Methods: A total of 25 type-2 diabetic patients with very low serum levels of 25-hydroxy vitamin D (severe deficiency – <10 ng/ml); and 25 type-2 diabetic patients with low serum levels of 25-hydroxy vitamin D (deficient – 10 to 30 ng/ml) were recruited in this cross-sectional study. Fasting plasma glucose (FBS), postprandial glucose (PPG), HbA1C, oxLDL, and high-sensitivity C-reactive protein (hs-CRP) were measured. Diagnostic accuracies were determined by receiver-operating characteristic (ROC) curve analysis and measuring the area under the curve (AUC).Results: Patients with severe vitamin D deficiency had higher FBS, PPG, HbA1C, and oxLDL than the vitamin D deficient group (P<0.05). We showed that the AUC of FBS, PPG, HbA1C, and oxLDL were in the range of 0.7-0.9, which indicates moderate accuracies in differentiating severe vitamin D deficiency from deficiency condition.Conclusion: In conclusion, diabetic patients with severe vitamin D deficiency had higher FBS, PPG, and oxLDL levels compared with deficient ones. ROC curve analysis of FBS, PPG, HbA1C, and oxLDL showed these markers are independent predictors of severe vitamin D deficiency and significantly discriminate between very low and low levels of vitamin D deficiency in patients with diabetes. Keywords: Type 2 diabetes mellitus. Vitamin D deficiency. OxLDL. Fasting blood glucose.
Breast fibroadenomas are less frequent in women with uterine fibroids
Authors: Moini Ashraf , Eslami Bita , Alipour Sadaf 
Published: August 2021

BACKGROUND: The etiology and incidence of Fibroadenoma (FA) as the most frequent benign breast mass and uterine fibroma (UF) as the most benign gynecological disorders are unknown. OBJECTIVE: Considering the dependency of FA and UF to sex hormones, our objective was to investigate the association of these two neoplasms. METHODS: Among women attending the hospital Gynecology Clinic, those with typical uterine fibroids in their pelvic ultrasound constituted cases and those with no pathology the controls. All participants underwent breast ultrasound for FA. Criteria for diagnosis of FA were a typical image for lumps <2 cm in women aged <40 and <1 cm in ages ≥ 40, and a histologic diagnosis for all other participants or larger lumps. RESULTS: The mean age of cases and controls was 42.4 and 41.7 years, respectively. FA were detected in 140 (23%) of all participants; 19.7% of the cases, and 26.2% of the controls (p = 0.07). FA and UF had a borderline reverse association (OR = 0.69, 95% CI = 0.46–1.02, p = 0.07). CONCLUSION: The incidence of FA is lower in patients with UF. Further studies are needed to find the selective effects of estrogen and progesterone on hormonal receptors of these two tumors.
Non-steroidal anti-inflammatory drugs and risk of acute adverse renal outcomes in diabetes and diabetic kidney disease
Authors: Lim Cynthia Ciwei , Kadir Hanis Bte Abdul , Tan Ngiap Chuan , Ang Andrew Teck Wee , Bee Yong Mong , Lee Puay Hoon , Goh Bandy Qiuling , Ang Alcey Li Chang , Xin Xiaohui , Kwek Jia Liang , Lam Amanda Yun Rui , Choo Jason Chon Jun 
Published: August 2021

BACKGROUND: Individuals with diabetes mellitus (DM) may be susceptible to non-steroidal anti-inflammatory drug (NSAID)-induced acute kidney injury (AKI) but data on NSAID-related adverse renal events is sparse. OBJECTIVE: We aimed to evaluate the risk of acute kidney injury and/or hyperkalemia after systemic NSAID among individuals with DM and diabetic chronic kidney disease (CKD). METHODS: Retrospective cohort study of 3896 adults with DM with incident prescriptions between July 2015 and December 2017 from Singapore General Hospital and SingHealth Polyclinics. Laboratory, hospitalization and medication data were retrieved from electronic medical records. The primary outcome was the incidence of AKI and/ or hyperkalemia within 30 days after prescription. RESULTS: AKI and/or hyperkalemia occurred in 13.5% of all DM and 15.8% of diabetic CKD. The association between systemic NSAID >14 days and 30-day risk of AKI and/or hyperkalemia failed to reach statistical significance in unselected DM (adjusted OR 1.62, 95% CI 0.99–2.65, p = 0.05) and diabetic CKD (adjusted OR 0.64, 95% CI 0.15–2.82, p = 0.64), but the odds of AKI and/or hyperkalemia were markedly and significantly increased when NSAID was prescribed with renin-angiotensin-aldosterone system (RAAS) blocker (adjusted OR 4.17, 95% CI 1.74–9.98, p = 0.001) or diuretic (adjusted OR 3.31, 95% CI 1.09–10.08, p = 0.04) and in the absence of diabetic CKD (adjusted OR 1.98, 95% CI 1.16–3.36, p = 0.01). CONCLUSION: NSAID prescription >14 days in individuals with DM with concurrent RAAS blockers or diuretics was associated with higher 30-day risk of AKI and/or hyperkalemia.
Investigation of heart rate variability of patients undergoing coronary artery bypass grafting using the statistical signal characterization method
Authors: Hossen Abdulnasir 
Published: August 2021

BACKGROUND: Autonomic function can be estimated non-invasively using heart rate variability (HRV). HRV of patients undergoing coronary artery bypass grafting (CABG) is investigated in time-domain and frequency-domain before and after CABG to study the effect of operation on the status of patients. OBJECTIVE: The main purpose of this work is to evaluate the effect of CABG surgery on patients with ischemic heart disease (IHD) before operation, and to monitor the status of patients on day 6 and day 30 after the CABG operation. METHODS: The statistical signal characterization (SSC) technique is used in this work in order to derive different morphology-based parameters to indirectly describe time-domain and frequency-domain HRV parameters in 24 patients undergoing CABG operation, before the operation (Group 1: G1), 6 days after operation (Group 2: G2) and 30 days after operation (Group 3: G3). The data is obtained from the Sultan Qaboos University Hospital in Oman. RESULTS: The SSC parameters Mean(mt) and Mean(dt) are reduced in all 24 patients and in 23 out of 24 patients in G2 compared to G1 (6-days after operation compared with before operation), respectively. Comparing G3 to G1 the reduction in Mean(mt) and Mean(dt) is noted in 18 of the 24 patients. CONCLUSIONS: The parameters Mean(mt) and Mean(dt) are successful parameters to follow the HRV for patients undergoing CABG surgery. A relation between those SSC parameters and the HRV time-domain and frequency-domain parameters is investigated in this paper to understand the physiological behavior of the patients.
Comparative Analysis of Naira/US Dollar Exchange Rate Volatility using GARCH Variant Modeling
Authors: Adi Agya Atabani , Kingsley Amadi W. , Hassan David Vincent 
Published: August 2021

This paper employed variant GARCH models to examined official, interbank and Bureau de change returns volatilities. Using monthly exchange rate of Naira/USD from January 2004 to September 2020 (2004:1-2020:9), the returns were not normally distributed and stationary at level. Ljung-Box Q statistic and Ljung-Box Q2 statistics of power transformed using power 0.25, 0.5 and 0.75 for conditional heteroscedasticity for lags of 6, 12 and 20 indicated present of conditional heteroscedascity in all returns.
The study found exchange rate volatility in Official, interbank and Bureau de change exchange rate returns were persistent. However, Bureau de change return was more persistent while official exchange rate return was the least persistent. Also, leverage effect exist in all the three exchange rate returns and asymmetric model were the best model for estimating exchange rate return while IGARCH was the worst model to estimate exchange rate return in Nigeria. There is need to incorporate news impact when developing exchange rate policy by monetary authority in Nigeria.
PENGARUH SISTEM PENGENDALIAN INTERN DAN PENERAPAN SISTEM AKUNTANSI KEUANGAN DAERAH TERHADAP KUALITAS LAPORAN KEUANGAN PEMERINTAH KABUPATEN INDRAGIRI HILIR
Authors: GUSTINA IRA 
Published: August 2021

Penelitian ini bertujuan untuk mengetahui pengaruh Sistem Pengendalian Internal Dan Penerapan Sistem Akuntansi Keuangan Daerah terhadap Kualitas Laporan Keuangan Pemerintah Kabupaten Indragiri Hilir Pada OPD Kabupaten Indragiri Hilir. Populasi dalam penelitian ini adalah Kasubbag Keuangan dan Bendahara Keuangan yang tentunya melaksanakan fungsi atau tanggung jawabnya terkait penyusunan laporan keuangan dan Sampel dalam penelitian ini sebanyak 50 orang yang mengisi kuesioner yang telah disebarkan. Metode Analisis data yang digunakan adalah regresi linier berganda, dengan pengujian uji asumsi klasik yang digunakan adalah uji normalitas data, uji multikolinieritas dan uji heterokedastisitas. Pengujian hipotesa uji –t dan uji koefisien determinasi (R2). Statistik deskriptif digunakan untuk membantu menganalisis data dengan mendeskripsikan data yang telah terkumpul.
Hasil penelitian ini menunjukkan bahwa persamaan regresi linier berganda yaitu Y= 12.715+0.011X1+0.309X2+ε. Uji secara parsial diketahui bahwa Sistem Pengendalian Intern (X1) tidak berpengaruh secara parsial terhadap Kualitas Laporan Keuangan Pada OPD Kabupaten Indragiri Hilir. Sistem Akuntansi Keuangan Daerah (X2) berpengaruh secara parsial terhadap Kualitas Laporan Keuangan Pada OPD Kabupaten Indragiri Hilir. Uji koefisien determinasi nilai Adjusted R Square sebesar 0,349 artinya adalah bahwa terdapat sebanyak 34,9% pengaruh variabel Kualitas Laporan Keuangan dipengaruhi oleh Sistem Pengendalian Internal dan Sistem Akuntansi Keuangan Daerah. Sedangkan sisanya sebesar 47,1% dipengaruhi oleh variabel lain yang tidak dimasukkan atau diteliti dalam penelitian ini.
Pengaruh Persepsi dan Preferensi Tamu Terhadap Keputusan Menginap di Hotel Syariah Kota Bandung
Authors: Karnita Ita , Rosdiana Aprilia Lu’luwatin 
Published: August 2021

This study aims to analyze how preceptions, preference and stay decision of syariah hotel guest in northern part of Bandung ((Hotel Noor, Hotel Narapati dan Hotel Darul Jannah). The method used in this research is quantitative methods. The population in this study were guest of syariah hotel in northern part of Bandung ((Hotel Noor, Hotel Narapati dan Hotel Darul Jannah). Sampling technique used in this method, while for calculating the amount of sample size using formula slovin. The number of respondent are 150 people. Probability sampling used as a technique sampling. Path analysis was used to analyze the result in this research. The result of this research showed thatstay decision influenced by the perception and preference. Perceptions influenced stay decision of syariah hotel guest more than preference variable.. The limited conditions of perceptions and preference will be impact to the low stay decision of guest. . In addition the research also showed that perceptions and preference significantly influence stay decision.
PROMOSI DAERAH DAN E – MARKETING PARIWISATA HALAL TERHADAP KEPUTUSAN BERKUNJUNG WISATAWAN DI YOGYAKARTA
Authors: Safira Raja Ela , Sholikah Winda , Rahmanto Dhidhin Noer Ady 
Published: August 2021

Abstract. Regional Promotion and E-Marketing of Halal Tourism against Tourist Visits in Yogyakarta. This research was conducted to find out how the influence of Halal Tourism Promotion Based on E-Marketing against Tourist Visits in Yogyakarta. Promotion is an important thing that needs to be considered in attracting tourists. In this millennial era, the development of technology very fast, many activities using technology. Furthermore, the using of E-Marketing more suitable for increasing the number of tourists. This research used multiple linear regression method with moderating variables to show the influence of Halal Tourism Promotion Based on E-Marketing Against Tourist Visits in Yogyakarta with data collection techniques used were questionnaires and observations. The result of this research was found that using E-Marketing can increase tourist’s interest to visit halal tourism in Yogyakarta. When using regional promotions only gained 7% and when using E-Marketing increased to 67%. Abstrak. Promosi Daerah dan E–Marketing Pariwisata Halal Terhadap Keputusan Berkunjung Wisatawan di Yogyakarta. Penelitian ini dilakukan untuk mengetahui bagaimana pengaruh Promosi Pariwisata Halal Berbasis E-Marketing Terhadap Keputusan Berkunjung Wisatawan di Yogyakarta. Promosi merupakan hal penting yang perlu dilakukan dan diperhatikan dalam menarik minat wisatawan. Di era milenial ini teknologi sangat berkembang dengan pesat, sehingga banyak aktivitas yang dilakukan menggunakan teknologi. Dengan demikian penggunaan E-Marketing dinilai cocok untuk meningkatkan wisatawan. Metode pengujian adalah dengan menggunakan metode regresi linier berganda dengan variabel moderating untuk menunjukkan hasil dari penelitian pengaruh Promosi Pariwisata Halal Berbasis E-Marketing Terhadap Keputusan Berkunjung Wisatawan di Yogyakarta. Teknik pengumpulan data yang digunakan adalah menggunakan kuesioner dan observasi. Dari hasil penelitian ini ditemukan bahwa penggunaan E-Marketing dapat meningkatkan minat wisatawan untuk berkunjung ke pariwisata halal di Yogyakarta. Pada awalnya ketika menggunakan promosi daerah hanya memperoleh sebesar 7% dan ketika menggunakian E-Marketing meningkat menjadi 67%.
Rancang Bangun Alat Pemberi Pakan Ikan Otomatis Pada Akuarium Berbasis Arduino Uno
Authors: Soekarta Rendra , Yapari Denny , Ackswan M. 
Published: August 2021

Pemeliharaan ikan hias sangat digandrungi banyak orang, tak kala masuk waktu pemberian pakan tiba kadang kita sering lupa dalam memberikan pakan, dan terkadang banyak juga ssang pemelihara punya ksesibukan tersendiri hingga lupa memberikan pakan pada ikan peliharaan. Dan banyak juga para penghobbyh ikan yang telah mempunyai fish deffer tapi sangat cepat sekali rusak dan kadang kerusakan tidak diketahui pemilik, dan ikan yang dipelihara dapat mati akibat tidak diberi pakan. Maka dari itu tujuan penelitian ini adalah untuk merancang alat pemberi pakan ikan otomatis. menggunakan arduino Uno, di lengkapi dengan notifikasi suara yang menggunakan dfplayer. Sistem ini akan bekerja dimana jika sensor ultrasonik, telah mengirimkan data bahwa pakan kurang dari 7cm maka sistem servo akan berputar ketika telah memasuki waktu pemberian pakan, dan jika pakan lebih dari 7cm sistem dfplayer, spiker dan lcd ini dapat membantu para penghobby ikan hias dalam pengawasan pakan ikan.
The Incoherent Fluctuation of Folate Pools and Differential Regulation of Folate Enzymes Prioritize Nucleotide Supply in the Zebrafish Model Displaying Folate Deficiency-Induced Microphthalmia and Visual Defects
Authors: Hsiao Tsun-Hsien , Lee Gang-Hui , Chang Yi-Sheng , Chen Bing-Hung , Fu Tzu-Fun 
Published: August 2021

Graphical AbstractFolate deficiency lowered intracellular 10-CHO-THF and 5-CH3-THF levels, interfered nucleotide formation, impaired cell proliferation, induced apoptosis and impeded vitamin A supply, leading to microphthalmia and obstructed visual ability.
The Chemokine CCL5 Inhibits the Replication of Influenza A Virus Through SAMHD1 Modulation
Authors: Silva Thauane , Temerozo Jairo R. , do Vale Gabriele , Ferreira André C. , Soares Vinícius Cardoso , Dias Suelen Silva Gomes , Sardella Gabriela , Bou-Habib Dumith Chequer , Siqueira Marilda , Souza Thiago Moreno L. , Miranda Milene 
Published: August 2021

Influenza A virus (IAV) is the main etiological agent of acute respiratory tract infections. During IAV infection, interferon triggers the overexpression of restriction factors (RFs), the intracellular antiviral branch of the innate immune system. Conversely, severe influenza is associated with an unbalanced pro-inflammatory cytokine release. It is unclear whether other cytokines and chemokines released during IAV infection modulate RFs to control virus replication. Among the molecules enhanced in the infected respiratory tract, ligands of the CCR5 receptor play a key role, as they stimulate the migration of inflammatory cells to the alveoli. We investigated here whether ligands of the CCR5 receptor could enhance RFs to levels able to inhibit IAV replication. For this purpose, the human alveolar basal epithelial cell line (A549) was treated with endogenous (CCL3, CCL4 and CCL5) or exogenous (HIV-1 gp120) ligands prior to IAV infection. The three CC-chemokines tested reduced infectious titers between 30% to 45% upon 24 hours of infection. Eploying RT-PCR, a panel of RF mRNA levels from cells treated with CCR5 agonists was evaluated, which showed that the SAMHD1 expression was up-regulated four times over control upon exposure to CCL3, CCL4 and CCL5. We also found that IAV inhibition by CCL5 was dependent on PKC and that SAMHD1 protein levels were also increased after treatment with CCL5. In functional assays, we observed that the knockdown of SAMHD1 resulted in enhanced IAV replication in A549 cells and abolished both CCL5-mediated inhibition of IAV replication and CCL5-mediated cell death inhibition. Our data show that stimuli unrelated to interferon may trigger the upregulation of SAMHD1 and that this RF may directly interfere with IAV replication in alveolar epithelial cells.
eCPR Combined With Therapeutic Hypothermia Could Improve Survival and Neurologic Outcomes for Patients With Cardiac Arrest: A Meta-Analysis
Authors: Duan Jingwei , Ma Qingbian , Zhu Changju , Shi Yuanchao , Duan Baomin 
Published: August 2021

Background: Extracorporeal membrane oxygenation with CPR (eCPR) or therapeutic hypothermia (TH) seems to be a very effective CPR strategy to save patients with cardiac arrest (CA). Furthermore, the subsequent post-CA neurologic outcomes have become the focus. Therefore, there is an urgent need to find a way to improve survival and neurologic outcomes for CA.Objective: We conducted this meta-analysis to find a more suitable CPR strategy for patients with CA.Method: We searched four online databases (PubMed, Embase, CENTRAL, and Web of Science). From an initial 1,436 articles, 23 studies were eligible into this meta-analysis, including a total of 2,035 patients.Results: eCPR combined with TH significantly improved the short-term (at discharge or 28 days) survival [OR = 2.27, 95% CIs (1.60–3.23), p &lt; 0.00001] and neurologic outcomes [OR = 2.60, 95% CIs (1.92–3.52), p &lt; 0.00001). At 3 months of follow-up, the results of survival [OR = 3.36, 95% CIs (1.65–6.85), p &lt; 0.0008] and favorable neurologic outcomes [OR = 3.02, 95% CIs (1.38–6.63), p &lt; 0.006] were the same as above. Furthermore, there was no difference in any bleeding needed intervention [OR = 1.33, 95% CIs (0.09–1.96), p = 0.16] between two groups.Conclusions: From this meta-analysis, we found that eCPR combined with TH might be a more suitable CPR strategy for patients with CA in improving survival and neurologic outcomes, and eCPR with TH did not increase the risk of bleeding. Furthermore, single-arm meta-analyses showed a plausible way of temperature and occasion of TH.
Outflow Through Aortic Side Branches Drives False Lumen Patency in Type B Aortic Dissection
Authors: Logghe Gerlinde , Trachet Bram , Segers Patrick , De Backer Julie , Mulorz Joscha , Dueppers Philip , Vermassen Frank , Schelzig Hubert , Van Herzeele Isabelle , Wagenhäuser Markus U. 
Published: August 2021

Objective: Thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (TBAD) aims to induce false lumen (FL) thrombosis by sealing intimal tears between the true (TL) and the FL, and blocking the inflow into the FL. Incomplete thrombosis of the FL is correlated with poor clinical outcome. We hypothesize that the number of major and minor branches arising from the FL affects FL patency and may negatively influence TEVAR induced FL thrombosis.Methods: Computed tomography (CT)-scans from 89 patients diagnosed with TBAD [best medical treatment (BMT) n = 52, TEVAR n = 37] from two high-volume vascular surgery centers were analyzed retrospectively. Analysis included evaluation of the FL patency status, the number, location and size of intimal tears, and the presence of minor and major side branches originating from the FL. Multiple regression analysis was conducted to evaluate obtained parameters as predictors for FL thrombosis status.Results: In univariate analysis, the strongest correlation for FL patency was found for the number of major (R = 0.79) and minor (R = 0.86) side branches originating from the FL. When applying a multiple linear regression model, the number of major (normalized beta 0.37; P &lt; 0.001) and minor (normalized beta 0.41; P &lt; 0.01) side branches arising from the FL were valid predictors for the axial length of the patent and non-patent FL, and additionally determined the length of the patent FL at 12-month follow-up in patients that underwent TEVAR.Conclusions: Our data suggest that the number of minor side branches that originate from the FL in TBAD is an important determinant of FL patency, to a greater degree than previously assumed.