bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coupling a Pest and Disease Damage Module with CSM-NWheat: A Wheat Crop Simulation Model
Authors: Berton Ferreira Thiago , Pavan Willingthon , Cunha Fernandes José Maurício , Asseng Senthold , Antunes de Oliveira Fabio Augusto , Amaral Hölbig Carlos , Noleto Luz Pequeno Diego , Dalmago Genei Antônio , Lazaretti Zanatta Alexandre , Hoogenboom Gerrit 
Published: December 2021

HighlightsCSM-NWheat, a DSSAT wheat crop model, was coupled with a pest module named PEST.The coupled model can simulate the impact of pest and disease damage on wheat crops.Pest damage is expressed in daily steps by communication links called coupling points.Coupling points are linked with state variables at which pest damage can be applied.Field pest-scouting reports and linear interpolation are used to compute damage rates.Abstract. Wheat is one of the most important global staple crops and is affected by numerous pests and diseases. Depending on their intensity, pests and diseases can cause significant economic losses and even crop failures. Pest models can assist decision-making, thus helping reduce crop losses. Most wheat simulation models account for abiotic stresses such as drought and nutrients, but they do not account for biotic stresses caused by pests and diseases. Therefore, the objective of this study was to couple a dynamic pest and disease damage module to the DSSAT model CSM-NWheat. Coupling points were integrated into the CSM-NWheat model for applying daily damage to all plant components, including leaves, stems, roots, and grains, the entire plant, and to the assimilate supply. The coupled model was tested by simulating a wheat crop with virtual damage levels applied at each coupling point. Measured foliar damage caused by tan spot (Pyrenophora tritici-repentis) was also simulated. The modified model accurately estimated the reduction in leaf area growth and the yield loss when compared with observed data. With the incorporation of the pest module, CSM-NWheat can now predict the potential impact of pests and diseases on wheat growth and development, and ultimately economic yield. Keywords: Biotic stress, Decision support, DSSAT, Model coupling, Yield loss.
Comparing evidence on the effectiveness of reading resources from expert ratings, practitioner judgements, and research repositories
Authors: Hollands Fiona M. , Pan Yilin , Kieffer Michael J. , Holmes Venita R. , Wang Yixin , Escueta Maya , Head Laura , Muroga Atsuko 
Published: December 2021

Background:Education decision makers are increasingly expected to use evidence to inform their actions. However, the majority of educational interventions have not yet been studied and it is challenging to produce high quality research evidence quickly enough to influence policy questions.
Aims and objectives:We set out to gather evidence on the efficacy of reading resources implemented at 23 struggling elementary schools in a large, urban district in the US. The schools were at risk of closure by the state.
Methods:For each reading resource, we searched for existing effectiveness studies and collected professional judgements by surveying practitioners. We also used an expert survey to collect judgements from three reading experts. We compared the ratings among experts and between practitioners and experts. We also compared practitioner and expert judgements to evidence summaries from research repositories.
Findings:We found evidence summaries in research repositories for only five of 23 reading resources used in the 23 schools. Experts showed poor to good agreement on ten questions about each resource. Agreement between practitioners and experts was low with practitioners generally rating resources more positively than reading experts.
Discussion and conclusions:Practitioners may be overly optimistic about the efficacy of educational materials while experts have difficulty assessing how well the materials serve an unfamiliar population. In the absence of rigorous evaluations of locally-implemented programmes, district decision makers can review the consistency of evidence collected from practitioners and experts, along with external research evidence, to inform actions towards supporting and guiding struggling schools.
A constrained method for lensless coherent imaging of thin samples
Authors: Soulez Ferréol , Rostykus Manon , Moser Christophe , Unser Michael 
Published: December 2021

Lensless inline holography can produce high-resolution images over a
large field of view (FoV). In a previous work [Appl. Opt.
60, B38 (2021)APOPAI0003-693510.1364/AO.414976], we
showed that (i) the actual FoV can be extrapolated outside of the
camera FoV and (ii) the effective resolution of the setup can be
several times higher than the resolution of the camera. In this paper,
we present a reconstruction method to recover high resolution with an
extrapolated FoV image of the phase and the amplitude of a sample from
aliased intensity measurements taken at a lower resolution.
Biological laterality and peripheral nerve DTI metrics
Authors: Holmes Scott A. , Staffa Steven J. , Karapanagou Anastasia , Lopez Natalia , Karian Victoria , Borra Ronald , Zurakowski David , Lebel Alyssa , Borsook David 
Published: December 2021

Background and purpose
Clinical comparisons do not usually take laterality into account and thus may report erroneous or misleading data. The concept of laterality, well evaluated in brain and motor systems, may also apply at the level of peripheral nerves. Therefore, we sought to evaluate the extent to which we could observe an effect of laterality in MRI-collected white matter indices of the sciatic nerve and its two branches (tibial and fibular).

Materials and methods
We enrolled 17 healthy persons and performed peripheral nerve diffusion weighted imaging (DWI) and magnetization transfer imaging (MTI) of the sciatic, tibial and fibular nerve. Participants were scanned bilaterally, and findings were divided into ipsilateral and contralateral nerve fibers relative to self-reporting of hand dominance. Generalized estimating equation modeling was used to evaluate nerve fiber differences between ipsilateral and contralateral legs while controlling for confounding variables. All findings controlled for age, sex and number of scans performed.

Results
A main effect of laterality was found in radial, axial, and mean diffusivity for the tibial nerve. Axial diffusivity was found to be lateralized in the sciatic nerve. When evaluating mean MTR, a main effect of laterality was found for each nerve division. A main effect of sex was found in the tibial and fibular nerve fiber bundles.

Conclusion
For the evaluation of nerve measures using DWI and MTI, in either healthy or disease states, consideration of underlying biological metrics of laterality in peripheral nerve fiber characteristics need to considered for data analysis. Integrating knowledge regarding biological laterality of peripheral nerve microstructure may be applied to improve how we diagnosis pain disorders, how we track patients’ recovery and how we forecast pain chronification.
Research on optimization of real-time efficient storage algorithm in data information serialization
Authors: Huang Bin , Tang You 
Published: December 2021

Background
Along with the vigorous development of Internet technology, increasing the functions of the various types of equipment, network communication easy and diversity, at the same time, the amount of data is very huge, under the network bandwidth limitations, through long lead to a data need to be cut into more, one by one, transfer times, information delay problems.

Results
Aiming at the problems of poor data integrity, low efficiency and poor serialization efficiency of traditional data storage information, this article introduces Protobuf technology to study the serialization of data storage information. The serpentine gap method is used to complete the allocation interval of the sequence nodes, so that the working state and the resting state always maintain a dynamic balance. According to the first-level rules, the storage data of the completed target node is obtained, and the grammatical structure and the semantics of the target data are analyzed, Meanwhile corresponding correspondences are established, and the data storage information is serialized. In order to verify the effectiveness of Protobuf’s data storage information serialization method, a comparative experiment is designed. By using three methods of HDVM, Redis and Protobuf to serialize JSON data, the comparative analysis shows that HDVM has the longest processing time and Protobuf has the shortest processing time, and the data integrity is not affected. The simulation data shows that the Protobuf serialization method has short conversion time, high space utilization, and the Obvious advantages in correctness and integrity. It is vary suitable for serialization of JSON data in the case of limited bandwidth.
Study protocol for a two-site clinical trial to validate a smartphone-based artificial intelligence classifier identifying cervical precancer and cancer in HPV-positive women in Cameroon
Authors: Baleydier Inès , Vassilakos Pierre , Viñals Roser , Wisniak Ania , Kenfack Bruno , Tsuala Fouogue Jovanny , Enownchong Enow Orock George , Lemoupa Makajio Sophie , Foguem Tincho Evelyn , Undurraga Manuela , Cattin Magali , Makohliso Solomzi , Schönenberger Klaus , Gervaix Alain , Thiran Jean-Philippe , Petignat Patrick 
Published: December 2021

Introduction
Cervical cancer remains a major public health challenge in low- and middle-income countries (LMICs) due to financial and logistical issues. WHO recommendation for cervical cancer screening in LMICs includes HPV testing as primary screening followed by visual inspection with acetic acid (VIA) and treatment. However, VIA is a subjective procedure dependent on the healthcare provider’s experience. Its accuracy can be improved by computer-aided detection techniques. Our aim is to assess the performance of a smartphone-based Automated VIA Classifier (AVC) relying on Artificial Intelligence to discriminate precancerous and cancerous lesions from normal cervical tissue.

Methods
The AVC study will be nested in an ongoing cervical cancer screening program called “3T-study” (for Test, Triage and Treat), including HPV self-sampling followed by VIA triage and treatment if needed. After application of acetic acid on the cervix, precancerous and cancerous cells whiten more rapidly than non-cancerous ones and their whiteness persists stronger overtime. The AVC relies on this key feature to determine whether the cervix is suspect for precancer or cancer. In order to train and validate the AVC, 6000 women aged 30 to 49 years meeting the inclusion criteria will be recruited on a voluntary basis, with an estimated 100 CIN2+, calculated using a confidence level of 95% and an estimated sensitivity of 90% +/-7% precision on either side. Diagnostic test performance of AVC test and two current standard tests (VIA and cytology) used routinely for triage will be evaluated and compared. Histopathological examination will serve as reference standard. Participants’ and providers’ acceptability of the technology will also be assessed. The study protocol was registered under ClinicalTrials.gov (number NCT04859530).

Expected results
The study will determine whether AVC test can be an effective method for cervical cancer screening in LMICs.
Insecticide-treated net (ITN) use, factors associated with non-use of ITNs, and occurrence of sand flies in three communities with reported cases of cutaneous leishmaniasis in Ghana
Authors: Akuffo Richard , Wilson Michael , Sarfo Bismark , Dako-Gyeke Phyllis , Adanu Richard , Anto Francis 
Published: December 2021

Background
The insecticide treated bed net (ITN) has been proven for malaria control. Evidence from systematic review also suggests benefits of ITN roll out in reducing the incidence of cutaneous leishmaniasis (CL) and other vector borne diseases.

Methods
Using a community-based cross-sectional study design, ITN use, factors associated with non-use of ITNs, and occurrence of sand flies were investigated in three communities with reported cases of CL in the Oti region of Ghana.

Results
A total of 587 households comprising 189 (32.2%), 200 (34.1%), and 198 (33.7%) households from Ashiabre, Keri, and Sibi Hilltop communities with de facto population of 3639 participated in this study. The proportion of households that owned at least one ITN was 97.1%. The number of households having at least one ITN for every two members was 386 (65.8%) and 3159 (86.8%) household population had access to ITN. The household population that slept in ITN the night before this survey was 2370 (65.1%). Lack of household access to ITN (AOR = 1.80; CI: 1.31, 2.47), having a family size of more than 10 members (AOR = 2.53; CI: 1.20, 4.24), having more than 10 rooms for sleeping in a household (AOR = 10.18; CI: 1.28, 81.00), having 2–4 screened windows (AOR = 1.49; CI: 1.00, 2.20), and having 8–10 screened windows (AOR = 3.57; CI: 1.25, 10.17) were significantly associated with increased odds of not sleeping in ITN the night before the survey. A total of 193 female sand flies were trapped from various locations within the study communities.

Conclusions
Factors associated with ITN non-use such as lack of household access to ITN should be incorporated into future efforts to improve ITN use. Species of sand flies and their potential vectorial role in the study communities should also be investigated.
Resistance pattern of infected chronic wound isolates and factors associated with bacterial resistance to third generation cephalosporins at Mbarara Regional Referral Hospital, Uganda
Authors: Khalim Wangoye , Mwesigye James , Tungotyo Martin , Twinomujuni Silvano Samba 
Published: December 2021

Background
The objectives of this study were; (I) to determine the proportion of pathogens isolated from patients with infected chronic wounds in the surgical ward of MRRH that are resistant to the third-generation cephalosporins and (II) to determine the factors associated with resistance to third-generation cephalosporins in the surgical ward of MRRH.

Method(s)
This study was a descriptive analytical survey of bacterial isolates from infected chronic wounds among patients admitted in the surgical ward of MRRH, Uganda. Seventy five (75) study participants were recruited in the study using convenient sampling technique. Bacterial culture and identification was performed using standard microbiology laboratory procedures whereas broth microdilution method was used to establish the susceptibility of the identified pathogens. Data for objective one (1) was summarized as proportions while the categorized variables were analyzed using logistic regression to determine whether they were associated with the resistance patterns. The level of significance was preset at 5% and p-values less than 0.05 were considered statistically significant.

Results
Generally, all isolates had complete susceptibility (100%) to Cefoperazone+Sulbactam 2g except 7.1% of proteus spp that were resistant. Of all the bacterial isolates studied, Staphylococcus aureus, Enterobacter agglomerans, providencia spp and pseudomonas earuginosa had complete resistance (100%) to Cefopodoxime 200mg while providencia spp and pseudomomas earuginosa had complete resistance (100%) to Cefixime 400mg and cefotaxime 1g. Finally, higher odds of bacterial resistance to more 2 brands of the third generation cephalosporins were observed among participants who had prior exposure to the third generation cephalosporins (OR, 2.22, 95% CI, 0.80–6.14), comorbidities (OR, 1.76, 95% CI, 0.62–4.96) and those who had more than two hospitalizations in a year (OR, 1.39, 95% CI 0.46–4.25). However, multivariate logistic regression was not performed since no factor was significantly associated with resistance to more than two brands of third generation cephalosporins (p >0.05).

Conclusion
This study found that cefixime and cefpodoixme had high rates of resistance and should not be used in routine management of infected chronic wounds. In addition, the factors investigated in this study were not significantly associated with bacterial resistance to more than two brands of third generation cephalosporins.
Short-term efficacy and safety of second generation bipolar transurethral vaporization of the prostate (B-TUVP) for large benign prostate enlargement: Results from a retrospective feasibility study
Authors: Fukazawa Takeshi , Ito Hiroki , Takanashi Masato , Shinoki Risa , Tabei Tadashi , Kawahara Takashi , Keeley Francis X. , Drake Marcus J. , Kobayashi Kazuki 
Published: December 2021

Background
To investigate the efficacy and safety of a second-generation bipolar transurethral electro vaporization of the prostate (B-TUVP) with the new oval-shaped electrode for large benign prostatic enlargement (BPE) with prostate volume (PV) ≥100ml.

Materials and methods
100 patients who underwent second-generation B-TUVP with the oval-shaped electrode for male lower urinary tract symptom (LUTS) or urinary retention between July 2018 and July 2020 were enrolled in this study. The patients’ characteristics and treatment outcome were retrospectively compared between patients with PV <100ml and ≥100ml.

Results
17/41 (41.5%) cases of PV ≥100ml and 24/59 cases (40.7%) of PV <100ml were catheterised due to urinary retention. The duration of post-operative catheter placement and hospital-stay of PV ≥100ml (3.1±1.3 and 5.6±2.3 days) were not different from PV <100ml (2.7±1.2 and 5.0±2.4 days). In uncatheterised patients (N = 59), post-void residual urine volume (PVR) significantly decreased after surgery in both groups, however, maximum uroflow rate (Qmax) significantly increased after surgery only in PV <100ml but not in PV ≥100ml. Voiding symptoms and patients’ QoL derived from International Prostate Symptom Score (IPSS), IPSS-QoL (IPSS Quality of Life Index) and BPH Impact Index (BII) scores, significantly improved after B-TUVP in both groups. Catheter free status after final B-TUVP among patients with preoperative urinary retention was achieved in 18/24 (75.0%) and 14/17 (82.1%) cases in patient with <100ml and ≥100ml, respectively. There was no significant difference in post-operative Hb after B-TUVP, which was 97.0±5.4% of baseline for PV <100ml and 96.9±6.1% for PV ≥100ml and no TUR syndrome was observed.

Conclusions
This is the first study investigating short-term efficacy and safety of second-generation B-TUVP with the oval-shaped electrode on large BPE. B-TUVP appears to be effective and safe for treating moderate-to-severe lower urinary tract symptoms and urinary retention in patients with large BPE.
Comparison of clinical manifestations of rheumatoid arthritis in patients with moderate or high disease activity depending on the presence or absence of symptoms of neuropathic pain
Authors: Polishchuk E. Yu. , Filatova E. S. , Karateev A. E. , Amirdzhanova V. N. , Nesterenko V. A. 
Published: December 2021

Objective: to study the effect of neuropathic pain symptoms (SNP) on the clinical manifestations of rheumatoid arthritis (RA) in patients with moderate or high disease activity.Patients and methods.The 1st (main) group included 58 RA patients (84.5% of women, age 53.0±11.9 years), in whom SNP were identified using the DN4 (≥4) and PainDETECT (≥13) questionnaires. The 2nd (control) group included 43 patients with RA (79.1% women, age 48.8±14.4 years) who did not have SNP (DN4 ≤4 and PainDETECT ≤13). All patients received disease-modifying antirheumatic drugs (mainly methotrexate and leflunomide), 20% – biologic disease-modifying antirheumatic drugs. We compared groups 1 and 2 for RA activity (DAS28, CDAI, SDAI), pain intensity on a visual analogue scale (VAS, 0–100 mm), functional impairment (HAQ), patient global assessment (PGA, VAS), number of painful and swollen joints, quality of life (EQ-5D), signs of anxiety and depression (HADS), CRP level.Results and discussion. The RA activity in patients of the 1st and 2nd groups did not differ statistically significantly. Patients of the 1st group showed significantly higher indicators of the severity of pain, PGA and anxiety than patients of the control group: 71.0±12.5 and 54.7±17.5 mm, respectively (p<0.001); 61.0±13.1 and 53.7±15.3 mm (p=0.045); 62.1 and 28.6% (HADS ≥7; p<0.001), respectively.Conclusion.SNP are associated with higher rates of pain intensity, PGA, and anxiety in RA patients with moderate to high disease activity.
La Gran Depresión y el COVID-19
Authors: Cortés Cenalmor Miguel 
Published: December 2021

La finalidad principal de este artículo es establecer un análisis comparativo entre la Gran Depresión, que tuvo lugar después del Crack de la bolsa de 1929, y la recesión económica generada por la pandemia de COVID-19. En la primera parte del artículo, se examinan las causas y antecedentes que provocaron la depresión económica mundial en los años treinta, así como el impacto global de la crisis y las políticas adoptadas por los diferentes gobiernos del mundo, prestando especial atención al New Deal de los Estados Unidos. Además, se analizan las principales implicaciones políticas que la Gran Depresión acarreó, centrándonos en el rol de la depresión en el éxito internacional del keynesianismo y el auge del nazismo en Alemania.
En la segunda parte, se analiza el impacto socioeconómico de la pandemia y las medidas de contención del virus a nivel mundial, como el distanciamiento social o los confinamientos domiciliarios, así como la efectividad de las políticas sociales y los planes de retención de empleo empleados para salvaguardar el empleo y proteger la economía. De este modo, se argumenta la existencia de determinadas similitudes/diferencias entre ambas crisis. Por último, el artículo finaliza con una reflexión sobre las posibles consecuencias políticas que los acontecimientos vividos durante el 2020 podrían augurar para el futuro de la democracia liberal.
Kościół św. Franciszka z Asyżu i klasztor Franciszkanów w Poznaniu w latach 1947-1957
Authors: Tomczak Salezy Bogumił 
Published: December 2021

IW 1947 r., po 111 latach nieobecności, powrócili do Poznania franciszkanie i objęli swój dawny klasztor i kościół pw. św. Franciszka z Asyżu, zniszczony w czasie II wojny światowej w 75%. Do 1957 r. zdołali odbudować kaplicę Matki Bożej Loretańskiej, kościół i klasztor. Od samego początku prowadzili działalność duszpasterską w swoim kościele, ponadto głosili misje ludowe i rekolekcje w wielu parafiach. Na życzenie arcybiskupa poznańskiego Walentego Dymka w 1949 r. zaprowadzili stały dyżur spowiadania. Nawiązując do starej tradycji zapoczątkowanej przez św. Franciszka z Asyżu, od 1949 r. w okresie Bożego Narodzenia budują okazały żłóbek, który przyciąga wielkie rzesze wiernych. Znaczniejsze uroczystości kościelne uświetniali swoim śpiewem klerycy poznańskiego seminarium duchownego i chór pod dyrekcją Stefana Stuligrosza.