bluuebunny/crossref_metadata_2025_split huggingface dataset:
A-121 Functional Outcomes in Bilingual Persons with Traumatic Brain: The Role of Mood
Authors: Olmos Winter , Lopez-Hernandez Daniel W , Munoz Isabel , Schierholz Laura , Rugh-Fraser Rachel A , Munoz Raelynn B , Nordberg Bethany A , Hovda David A , McArthur David L , Vespa Paul , Fuster Joaquin M , Woo Ellen , Lopez Enrique , Hardy David J , Wright Matthew J 
Published: August 2021

Abstract

Introduction
We examined the relationship between depression and anxiety, language, and functional outcomes in persons with traumatic brain injury (TBI).

Methods
The sample consisted of 48 acute TBI (ATBI: 23 Spanish-English Bilinguals; 25 English monolinguals), 30 chronic TBI (CTBI: 17 Spanish English Bilinguals; 12 English monolinguals), and 47 healthy comparison (HC: 29 Spanish-English Bilinguals; 18 English monolinguals) participants. The Hospital Anxiety and Depression Scale was used to measure depression (HADS-D) and anxiety (HADS-A). The Mayo Portland Adaptability Inventory-4 (MPAI-4) was used to measure functional outcomes (ability, adjustment, participation).

Results
An ANCOVA, controlling for age, revealed the ATBI group reported lower anxiety levels compared to the CTBI group, p = 0.034 np2 = 0.06. HC participants demonstrated significantly higher functional ability compared to both TBI groups, p &lt; 0.05, np2 = 0.08–0.19. The ATBI group demonstrated worse participation scores compared to the CTBI and HC groups, p = 0.001, np2 = 0.11. Pearson correlations revealed mood was related to functional status in ATBI monolinguals (HADS-A: r = 0.29–0.64; HADS-D, r = 0.49–0.62). Monolingual participants with ATBI demonstrated correlations between depressive symptoms and functional adjustment (r = 0.57, p = 0.005) and ability (r = 0.44, p = 0.034). For monolinguals with CTBI, HADS-A correlated with functional outcomes, r = 0.60–0.66, p &lt; 0.05. For bilinguals with CTBI, functional outcomes correlated with HADS-A, r = 0.53–0.66, p &lt; 0.05, and HADS-D, r = 0.54–0.66, p &lt; 0.05. For HC monolinguals, functional outcomes correlated with HADS-A, r = 0.53–0.70, p &lt; 0.05, and HADS-D, r = 0.50–0.72, p &lt; 0.05. Finally, for HC bilinguals, functional outcomes correlated with HADS-A, r = 0.59–0.68, p &lt; 0.05.

Conclusion
Our results suggest that a relationship between anxiety and depressive symptoms is related more to functional outcomes in monolingual TBI survivors compared to bilingual TBI survivors.
A-128 Intraindividual Neurocognitive Variability Is Associated with Poorer Prospective Memory in OEF/OIF/OND Veterans with Comorbid Mild Traumatic Brain Injury History and Current Posttraumatic Stress Disorder
Authors: Sheppard David , Rau Holly P , Werhane Madeleine , Peskind Elaine R , Pagulayan Kathleen 
Published: August 2021

Abstract

Objective
Mild Traumatic Brain Injury (mTBI) and Posttraumatic Stress Disorder (PTSD) frequently co-occur in service members, and each are associated with increased neurocognitive intraindividual variability (IIV), a proposed indicator of subtle disruptions in executive control, and prospective memory (PM), or “remembering to remember.” The current study sought to examine possible associations between IIV and PM performances among Veterans with comorbid mTBI and PTSD.

Methods
46 OEF/OIF/OND Veterans with a history of mTBI and current PTSD enrolled in a VA research study of mTBI completed a standardized neurocognitive battery of 12 measures used to calculate the coefficient of variation (CoV) as an index of IIV, and the Memory for Intentions Screening Test (MIST) as a measure of PM. Veterans also completed clinical questionnaires (i.e., Patient Health Questionnaire-9, PTSD Checklist-Military), and a subset of the sample (n = 31) Veterans completed the Prospective and Retrospective Memory Questionnaire (PRMQ) as a measure of self-reported PM.

Results
Controlling for age and education, higher CoV was associated with time-based MIST scores (β = −0.02, p = 0.008, η2 = 0.16) and event-based MIST scores (β = −0.02, p = 0.031, η2 = 0.11). CoV was not associated with mood factors in the sample (ps &gt;0.10). In a subset of the total sample, higher CoV was associated with elevated self-reported PM symptoms (r = −0.36, p = 0.046).

Conclusions
Among Veterans with a history of mTBI and current PTSD, elevated variability of performances across neurocognitive measures was associated with poorer performance-based PM and self-reported PM symptoms. Future studies are needed to examine IIV as a predictor of real-world PM performances (e.g., medication adherence).
A-129 The Association between Parental Migraine History and Persistent Post Traumatic Headaches
Authors: Owens Ronnise , Smith Sherly , Marker Craig 
Published: August 2021

Abstract

Objective
Literature indicates persistent concussive symptoms beyond the typical recovery time of days or weeks are attributable to factors other than concussion or mild traumatic brain injury (mTBI) (Scott et al., 2020). Post traumatic headaches (PTH) are a frequent complaint of pediatric patients who have sustained a mTBI. Research have indicated that parental migraine and mTBI may put children at risk for PTH (Whitecross, 2020). This systematic review aims to further investigate the relationship between parental history of migraine and PTH in pediatric patients who have sustained a concussion.

Data Selection
A search was conducted using, Medline, PubMed, and Google Scholar databases with the terms “pediatric”, “concussion”, “parental”, and “headache” between 2011 and 2021. A total of 200 relevant articles were screened and 14 were selected for this review. Exclusion criteria included studies unrelated child migraines, concussion or mTBI diagnosis, and parental history.

Data Synthesis
A review of literature indicates a 42% heritability and earlier onset of migraine diagnosis for children with parental migraine history (Dao et al., 2018; Eidlitz-Markus et al 2015). This indicates a significant risk factor for persistent post concussive symptoms and possibly direct implications in the slower rate of recovery (Sufrinko et al., 2018).

Conclusion
Overall, this systematic review strongly suggests that a genetic predisposition for migraines may serve as a catalyst for onset and duration of PTH and the earlier diagnosis of pediatric migraines. Consideration of these predispositions can aid the multidisciplinary approach to improve cognitive and neurobehavioral health in the pediatric population.
A-133 Emotion Regulation Strategy Use in Veterans with Subjective Cognitive Complaints in a Neuropsychology Clinic
Authors: Austin Tara , Pazienza Shawneen , Lantrip Crystal 
Published: August 2021

Abstract

Objective
Neuropsychological evaluations reveal individuals with both objective and subjective cognitive complaints. Subjective cognitive complaints (SCC) are often related to potentially modifiable factors, such as mood. One proposed treatment for cognitive complaints is to focus on emotion regulation rather than cognitive rehabilitation. This project examines acceptability and feasibility from the perspective of participants, and determines participant understanding of the relationship between mood and cognition following a brief, one session emotion regulation intervention.

Method
Two study authors interviewed a subgroup of participants enrolled in a larger longitudinal intervention study about their understanding of the impact of mood on cognitive functioning, the acceptability of the intervention, and ease of using the provided strategies. Study authors then used inductive coding to identify common themes in participants’ responses.

Results
Preliminary results reveal the following themes: 1. Participant understanding that current cognitive concerns are related to modifiable factors (e.g., sleep, pain, emotional distress) rather than damage to brain structures or a neurodegenerative process. 2. Participants’ need for attentional and memory strategies to consistently use emotional regulation strategies day to day as well as participate fully in adjunctive psychological treatment. 3. Post-intervention awareness of high levels of everyday rumination.

Conclusion
Individuals with SCCs are amenable to psychological intervention, particularly when delivered with a brain-behavior explanation of how modifiable factors contribute to cognitive difficulties. In order to most successfully apply these strategies, participants may also benefit from targeted cognitive strategies to improve their use of emotion regulation strategies.
A-146 Parent Responses on the Behavior Rating Inventory of Executive Function-2 Are more Reflective of Child Cognitive Functioning than Teacher Responses
Authors: Larson Kera , Wilbur Jessica , Hamilton Elizabeth 
Published: August 2021

Abstract

Objective
The Behavior Rating Inventory of Executive Function, Second Edition (BRIEF-2) is widely used to assess executive processes in children and adolescents. The BRIEF-2 manual (2015) indicates small correlations between executive functioning and intellectual performance on the Wechsler Intelligence Scales for Children, Fourth Edition, but no studies have evaluated the BRIEF-2 and the Woodcock Johnson Tests of Cognitive Abilities, Fourth Edition (WJ-IV-Cog). The current study examined whether parent and teacher BRIEF-2 responses were linked to WJ-IV-Cog indices in a rural school-based sample.

Method
A sample of (n = 18) students attending rural school districts was extracted from an archival dataset. Participants (age range 7–17, M = 12.9, SD = 2.5) included 15 males and 3 females, who were referred for psychoeducational assessment.

Results
Correlational analyses indicated a moderate relationship between the BRIEF-2 parent Global Executive Composite (GEC) and the WJ-IV-Cog domains of comprehension-knowledge (Gc), fluid reasoning (Gf), and auditory processing (Ga) (p &lt; 0.05). Subsequent analyses of the three BRIEF-2 indices showed that the Parent Behavioral Regulation Index (BRI) was related to both Gc and Gf (p &lt; 0.05), while the Parent Cognitive Regulation Index (CRI) was significantly associated with Gc, Gf, and Ga (p &lt; 0.05). Teacher ratings of GEC, BRI, and CRI were independent from child intellectual performance. However, Teacher Emotion Regulation Index (ERI) was moderately related with GIA (p &lt; 0.05).

Conclusion
Current findings support a moderate relationship between parent ratings on the BRIEF-2 and specific cognitive domains on the WJ-IV-Cog. Results should be interpreted within the context of both a small sample size and the designation of subjects for psycho-educational assessment evaluations.
A-153 Neuropsychological Effects Assessed Using WISC-IV and WISC-V
Authors: Verani Saba , Golden Charles 
Published: August 2021

Abstract

Objective
This review explores The Weschler Intelligence Scale for Children – Fourth Edition (WISC-IV) and the Weschler Intelligence Scale for Children – Fifth Edition (WISC-V) administered to children with various medical histories including traumatic brain injury, vascular conditions, brain tumor, epilepsy, strokes, sickle cell disease, down syndrome, and neurotoxicity on neurodevelopment. This review aims to explore neuropsychological effects of these medical conditions derived from final scores and scale comparisons.

Data Selection
Peer-reviewed studies between 2000 and 2020 were gathered from EBSCO, Google Scholar, and Science Direct. Criteria was limited to neurological conditions present in children, who were required to be assessed using either WISC-IV or WISC-V. Children with other developmental or learning disabilities were excluded. Data on Weschler Adult Intelligence Scale (WAIS) were excluded along with any other assessment administered to children. Thirteen articles were included based on the criteria along with two articles that discuss the validity of WISC.

Data Synthesis
The components of the WISC-IV or WISC-V demonstrated low average or below average scores on many scales, especially overall FSIQ. The largest impairments were present in Processing Speed Index, Verbal Comprehension Index, Working Memory Index, Visual Spatial Index, and overall FSIQ. All children assessed with preexisting neurological conditions demonstrated deficits in neuropsychological domains. The severity of the neurological condition significantly impacted scores when compared to children with no conditions.

Conclusions
The administration of WISC-IV and WISC-V demonstrated neuropsychological and functioning impairments in children with preexisting neurological conditions. The assessment successfully identified deficit areas and earlier testing can encourage earlier treatments.
A-158 Case Study: Cognitive Deficits Associated with Postoperative Intracranial Hemorrhage Following Meningioma Resection
Authors: Indorewalla Khushnoo K , Phenis Richard 
Published: August 2021

Abstract

Objective
Postoperative intracranial hemorrhages (PIH) are an infrequent complication following cranial tumor resection and associated with prolonged hospitalization as well as long-term neurologic deficits. There is limited research examining the neuropsychological deficits resulting from PIH following meningioma resection, especially with neuropsychological data. Here, we present the neurocognitive profile of a patient who underwent a meningioma resection surgery and subsequently suffered a PIH within the resection cavity.

Method
Mr. Doe is a bilingual male in his late 40s who developed right-side vision loss and an isolated incidence of disorientation, resulting in discovery of a left anterior clinoid meningioma. He underwent a left frontotemporal craniotomy for gross total resection of the mass a month after discovery. Postoperative neuroimaging the following day revealed the appearance of a hematoma and intracranial hemorrhage within the resection cavity, resulting in right hemiplegia, aphasia, and ophthalmoplegia. He underwent neuropsychological evaluation 15 months post-resection, to assess residual cognitive deficits following his hospitalization and subsequent inpatient rehabilitation.

Results
In the context of average premorbid intellectual functioning, Mr. Doe’s neurocognitive profile was notable for deficits in processing speed, receptive and expressive language, and executive functioning associated with speed/verbally mediated tasks. Testing revealed lateralized deficits indicative of left (language-dominant) hemisphere dysfunction secondary to meningioma resection and subsequent PIH within the resection cavity.

Conclusion
The current poster aims to contribute to the limited body of literature examining residual neuropsychological deficits resulting from PIH following intracranial resection of meningioma. This is especially crucial given that long-term cognitive deficits can negatively impact patients’ quality of life over time.
A-169 Remote Cognitive Screening: A Preliminary Study of Location Administration of the Boston Cognitive Assessment (BoCA)
Authors: Ferguson Hayden , Turok Nora , Colby Kelly Ann , Gold Dov , Piryatinsky Irene 
Published: August 2021

Abstract

Objective
Digital, remote, cognitive assessment has become crucial for efficient screening of patients cognitive concerns. The Boston Cognitive Assessment (BoCA) is a brief, digital, global screening instrument that can be administered both in-office on a laptop, or remotely from patients’ homes. Potential differences in performance from completing the BoCA in-office versus completing it at home remain uninvestigated. As such, this study aimed to compared performances across these settings among demographically and cognitively matched patient samples.

Method
Data from 35 cognitively healthy participants who completed the BoCA (18 administered in-office; 17 remotely administered) were retroactively collected; groups were matched by age, education, gender, ethnicity, and global cognitive functioning based on their scores on a separate screening instrument. Overall BoCA scores (total = 30) as well as performance on the eight BoCA subscales (Immediate Recall, Delayed Recall, Verbal Reasoning, Visuospatial Reasoning, Executive Functions, Attention, Mental Math, and Orientation) were compared using nonparametric testing.

Results
A Contingency analysis and an independent samples Mann–Whitney U test confirmed the demographic and cognitive similarities between the two groups. Comparisons of BoCA scores revealed no differences in total scores or any of the BoCA subscales between those who completed the BoCA in-office and those who completed it remotely.

Conclusion
Results from the present study suggest that performance on the BoCA is not influenced by one’s environment at the time of administration. This further adds to the utility of the BoCA as a remote, self-administered, global screening instrument, and may support its adoption in settings where serial screening is indicated.
A-179 Personality Assessment Inventory Cognitive Bias Scale of Scales (CB-Sos): Replication and Comparison to the CBS in an Active Duty Military Sample
Authors: Armistead-Jehle Patrick , Ingram Paul B , Morris Nicole M 
Published: August 2021

Abstract

Objective
The Cognitive Bias Scale (CBS) was developed for the PAI using item-level responses identified based on failed performance validity testing (PVT), with subsequent studies cross-validating the scale. New research developed three alternative forms of the CBS using scale level responses, called the Cognitive Bias Scale of Scales (CB-sos). This study examines the performance of the three different CB-sos scales based on performance on stand-alone PVTs in a military sample.

Methods
Retrospective review of 257 active-duty military individuals referred for outpatient neuropsychological assessment. Each subject was administered the PAI, MSVT, and NV-MSVT. Groups were defined as valid (0 PVT failures) or invalid (1 or more PVT failures), consistent with CB-sos validation. Independent t-tests, effect size estimates, and sensitivity/specificity estimates were then calculated.

Results
Significant t-tests (p &lt; 0.001) and medium effect sizes (0.5 &lt; d &lt; 0.8) were evident across each version of the CBS scale. The largest effect sizes were for the 7-scale CB-sos3 (d = 0.77) and the item-derived CBS (d = 0.70). AUC was similar (AUC = 0.686–0.713) across all scales. Estimates of sensitivity were low (ranging from 0.06 to 0.13) and specificity was high (ranging from 0.94 to 0.98) at the recommend cut values for each scale.

Discussion
It appears Scale of Scale validity indictors calculated from total scale scores, rather than items (i.e., CBS), produce similar levels of effectiveness. Results support the use of the CB-sos scales as potentially useful indicators of invalid responding on the PAI within a military sample (particularly CB-sos3), though sensitivity is relatively low.
A-181 Do Effortful Epilepsy Patients Fall Below Performance Validity Test Cutoffs at Higher Rates than Is Considered Acceptable?
Authors: Kang Hyun Jin , Kim Michelle , Torres Karen 
Published: August 2021

Abstract

Objective
Factors specific to an epilepsy population (e.g., medications, psychiatric comorbidities, localization) may result in higher false positive rates on performance validity tests (PVT), rendering the results more equivocal. This study examined whether specificity is reduced in effortful epilepsy patients on the Warrington Recognition Memory Test - Words (WRMT-W) and Test of Memory Malingering (TOMM).

Method
53 epilepsy patients referred for neuropsychological evaluation through the University of Washington Regional Epilepsy Center were examined. Patients were majority male (56.6%) and Caucasian (79.2%). Average age and education were 36.1 (SD = 13.03) and 13.4 years (SD = 2.39), respectively. Patients with an intelligence quotient of &lt;70, history of brain surgery, and those who seized during testing were excluded. Patients clinically observed to have reduced effort with 2+ PVT failures were excluded (n = 3). Frequency tables for WRMT-W and TOMM performances were utilized to examine specificity based on prior cutoffs identified for these measures.

Results
The WRMT-W cutoff of ≤42 was associated with 88.7% specificity. TOMM Trial 2 and Retention cutoffs of &lt;45 were associated with 98.1% and 100% specificity, respectively. The WRMT-W cutoff was associated with 91.7% specificity in language dominant hemisphere onset epilepsy patients (n = 16). None performed below cutoffs on the TOMM. All nondominant hemisphere onset patients (n = 8) performed above WRMT-W and TOMM cutoffs.

Conclusions
Use of the WRMT-W and TOMM in an epilepsy population is associated with an acceptable false positive rate (specificity around 90%). However, future studies examining the sensitivity of these measures in epilepsy patients should be performed.
A-184 Performance Validity Test Failure Rates in Bilingual Individuals Evaluated in English
Authors: Davis Jeremy , Hromas Gabrielle , Rolin Summer 
Published: August 2021

Abstract

Objective
Classification accuracy of embedded performance validity tests (PVTs) is unknown in cases involving bilingual examinees evaluated in English. This study examined false positive rates in bilingual individuals in an older adult sample.

Method
The project involved secondary analysis of a deidentified dataset (N = 22,688) from the National Alzheimer’s Coordinating Center (NACC). Exclusion criteria were diagnosis of mild cognitive impairment (MCI; n = 5160) or dementia (n = 5550). The initial sample included 11,513 participants grouped as cognitively normal (89.6%) or impaired but not MCI. A subset of 275 participants was identified with a primary language other than English who were evaluated in English. Propensity score matching was conducted by diagnostic group to match bilingual to monolingual participants on age, education, gender, and MMSE score. The final sample included 450 and 100 participants in normal and impaired groups, respectively. Failure rates on five embedded PVTs in the NACC cognitive test battery were examined by language and by diagnosis.

Results
Age, education, gender, and MMSE score were not significantly different by language in either diagnostic group. In the normal group, 4.9% of bilingual and 2.2% of monolingual participants failed two or more PVTs (n.s.). In the impaired group, 12% of bilingual and 6% of monolingual participants failed two or more PVTs (n.s.).

Conclusions
PVT failure rates were not significantly different between bilingual participants evaluated in English and monolingual participants in either diagnostic group. Failure rates, however, increased slightly above a common false positive threshold of 10% in bilingual participants in the impaired group.