bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sequential Pneumonitis with Ground-glass Opacity during Durvalumab Therapy after Chemoradiation for Stage III Non-Small Cell Lung Cancer
Authors: Kawamura Mitsue , Araki Norio , Kishi Noriko , Suwa Tatsuya , Daido Sayaka , Hirokawa Yuusuke , Mio Tadashi 
Published: June 2021

Abstract
Background: To investigate the clinical characteristics, radiographic pattern, and clinical course of radiation pneumonitis and programmed death ligand 1 inhibitor-related pneumonitis in patients with stage III non-small cell lung cancer (NSCLC) after definitive concurrent chemoradiotherapy (CCRT).Methods: We retrospectively reviewed 22 patients who received definitive CCRT and consolidative Durvalumab for NSCLC between February 2018 and December 2019 at our hospital. Chest computed tomography scans were reviewed to assess the incidence, timing, relation to the field of radiotherapy, and radiographic patterns of pneumonitis.Results: Among the 22 patients, six (27.3 %) developed grade 2 radiation pneumonitis. The median time from therapy initiation to pneumonitis was 1.5 months. Three patients had pneumonitis within the radiation treatment field, and the other three had pneumonitis spread outside the field. The radiographic pattern was organizing pneumonia with ground-grass opacity in five patients. All patients received corticosteroid therapy, and no patient experienced progression to grade 5 pneumonitis or recurrent pneumonitis after Durvalumab retreatment.Conclusion: It is essential to understand the mechanism and radiographic pattern of immunotherapy-related pneumonitis and radiation pneumonitis to manage this potentially severe adverse event promptly.
Effects of Laser Acupuncture on Constipation in Patients With Advanced Cancer: Study Protocol for a Double-blinded, Randomized Controlled Trial
Authors: Chen Jen-Ming , Chen Chao-Tung , Wu Bei-Yu , Chen Yung-Hsiang , Liu Chun-Ting 
Published: June 2021

Abstract
BackgroundConstipation is a common, uncomfortable, and frustrating complication in patients with advanced cancer which in turn affects the patient’s quality of life. The aim of this study is to investigate the effects of laser acupuncture on constipation.MethodsThis is a prospective, single-center, double-blinded, randomized controlled trial study. A sample of 74 participants will be randomly assigned to either the verum or the sham laser acupuncture group in a 1:1 ratio. The participants will receive laser acupuncture or sham laser acupuncture once a day for consecutive six days on eight acupoints (LI4, LI11, PC6, ST36, ST37, ST39, SP4, and SP9). The number of complete spontaneous bowel will be used primarily for the evaluation, and symptoms of constipation, comfort levels during defecation, and colonic motility will be also be measured. Data will be analyzed using the chi-square test or t-test. Analysis of covariance will be used to examine the differences on symptoms of constipation between two groups and adjusted for their respective baseline levels. DiscussionThis trial may provide evidence for improving the short-term benefit for advanced cancer patients by relieving the symptoms caused by constipation. As a result, further reduce the usage of medications, and lower the side effects due to medications.Trial registration: ClinicalTrials.gov, NCT04318808. Registered on 24 March 2020.
The Lifestyles of Palestinians during Corona Virus Pandemic: A cross sectional Study from Palestinian West Bank
Authors: Natour Nihal , Al-Tell Mariam 
Published: June 2021

Abstract
Introduction: Corona virus pandemic was associated with restriction on movement and perceived danger among the public but changes in the lifestyle and mental-wellbeing aspects were not studied in Palestinian PeopleAims: We aimed to study the changes in lifestyle and mental wellbeing aspects of Palestinian society.Methods: A translated questionnaire was produced through google forms and was administered through social media and university platforms including demographic variables, mental wellbeing issues, and lifestyle aspects. Data was analyzed by SPSS 21.Results: 152 adults participated in the study, they were 25± 9 y, 67% were females, 47% were from villages and 47% were from cities. 82% were with bachelors degree. 13% had COVID, 13% lost dear relative due to COVID, and commitment to restrictions was present in 14%. There was high prevalence of negative feelings including sadness, hopelessness and anxiety. Study participants consumed low amount of fruits and vegetables, had a lot of soft drinks, but they in general were physical active. ConclusionThe corona virus pandemic is associated with negative impact on lifestyle and mental wellbeing
Sources, spatial distribution and abundance of marine debris on Thondi coast, Palk Bay, Southeast coast of India
Authors: Perumal Karthikeyan , Boopathi Vishwanath , Chelladurai Stella , Muthuramalingam Subagunasekar , Raja Prakash 
Published: June 2021

Abstract
Background: The Thondi coast is a rich source of valuable natural marine resources, as well as many socioeconomically significant activities like agriculture, aquaculture, and fishing. The area receives an excess of untreated solid and liquid waste as a result of these activities. The study focus on the abundance, distribution, and status of the Clean - Coast Index (CCI) of marine debris from the Thondi coast, Palk Bay, Southeast coast of India. This research was the first to assess the type and quantity of marine debris on the Thondi coast. Results: A total of 1636 marine debris items/m2 and 4.09 density of the items/m2 were determined in the marine debris: plastics (77.49%), cotton swabs (8.62%), cigarette butts (10.15%), and food containers (3.73%). From the result, the CCI is ranged between 4.25 (clean) and 20.4 (extremely dirty) with a mean of 8.92 (moderate) in the Thondi coast assessed. Conclusion: These studies were conducted for the first time in this region. Finally, the high CCI value of 20.4 in the coast indicates that the marine debris pollution levels are high at the time of sampling in the middle part of the Thondi coast (most of the beach is covered with plastic) due to land – based marine debris (62.45%), sea – originated marine debris (21.14%) and unknown sources (16.41%) of the items. Our findings serve as a baseline for potential evaluations of marine environments. Input prevention should be the goal of management efforts, which include proper waste management, plastic recycling, and stringent penalties for illegal waste dumping.
Burden and factors associated with Perceived stress among the general population in Pakistan during the Corona-virus disease 2019
Authors: Lakhdir Maryam Pyar Ali , Peerwani Ghazal , Azam Syed Iqbal , Nathwani Apsara Ali , Iqbal Romaina , Asad Nargis 
Published: June 2021

Abstract
Background: The COVID-19 pandemic has paved the way for psychological crises, especially in resource-limited settings where mental health infrastructure is already crippled. This study aims to determine the prevalence and factors associated with perceived stress in the Pakistani population during the Covid-19 pandemic. Methods: A web-based cross-sectional survey was conducted on 1679 Pakistani residents who received the study questionnaire's Google form link. We used a validated tool of perceived-stress scale-10 to screen perceived stress levels. Multiple Ordinal Regression was used to identify the factors associated with perceived stress, and the results are reported as adjusted odds ratios with 95% confidence intervals. Results: The mean score of perceived stress was 19.32 (SD=+6.67). Most of the participants screened positive for moderate (69%) and high levels (14%) of stress, respectively. A significant interaction was seen between generalized-anxiety and the phase of the lockdown. The odds of high-perceived stress among severely anxious participants were 44.67(95% CI: 21.33, 93.53) times than participants with no/minimal generalized anxiety during the complete lockdown. Moreover, the odds of high levels of perceived-stress among moderately anxious respondents were 15.79(95% CI: 10.19-24.28) times compared to participants with no/minimal anxiety during the smart lockdown. Conclusion: This study evidences that the pandemic was highly distressing for the Pakistani population causing the maximum level of perceived-stress in more than half of the population. Adequate and timely interventions are needed before high-stress levels culminate into psychological disorders.
Qmin: A machine learning-based application for mineral chemistry data processing and analysis
Authors: Silva Guilherme Ferreira da , Ferreira Marcos Vinicius , Costa Iago Sousa Lima , Bernardes Renato Borges , Mota Carlos Eduardo Miranda , Jiménez Federico Alberto Cuadros 
Published: June 2021

Abstract
Mineral chemistry analysis is a valuable tool in several phases of mineralogy and mineral prospecting studies. This type of analysis can point out relevant information, such as concentration of the chemical element of interest in the analyzed phase and, thus, the predisposition of an area for a given commodity. Due to this, considerable amount of data has been generated, especially with the use of electron probe micro-analyzers (EPMA), either in research for academic purposes or in a typical prospecting campaign in the mineral industry. We have identified an efficiency gap when manually processing and analyzing mineral chemistry data, and thus, we envisage this research niche could benefit from the versatility brought by machine learning algorithms. In this paper, we present Qmin, an application that assists in increasing the efficiency of mineral chemistry data processing and analysis stages through automated routines. Our code benefits from a hierarchical structure of classifiers and regressors trained by a Random Forest algorithm developed on a filtered training database extracted from the GEOROC (Geochemistry of Rocks of the Oceans and Continents) repository, maintained by the Max Planck Institute for Chemistry. To test the robustness of our application, we applied a blind test with more than 11,000 mineral chemistry analyses compiled for diamond prospecting within the scope of the Diamante Brasil Project of the Geological Survey of Brazil. The blind test yielded a balanced classifier accuracy of ca. 99% for the minerals known by Qmin. Therefore, we highlight the potential of machine learning techniques in assisting the processing and analysis of mineral chemistry data.
Innovative Work Behavior among Teachers in Malaysia: The Effects of Teamwork, Principal Support, and Humor
Authors: Johari Aduni , Abdul Wahat Nor Wahiza , Zaremohzzabieh Zeinab 
Published: June 2021

Abstract: The Fourth Industrial Revolution (Industry 4.0) gives impetus to educational reform. Education experts have recently recognised the benefits of using technology in learning and teaching. They believe that innovations will shape Education 4.0 and that teachers will need to be prepared to build creative learning environments that support student creativity. Thus, the main purpose of this paper is to examine the relationships between teamwork, principal support, humor, and innovative work behaviour (IWB) among teachers. This study was conducted using a questionnaire, with a sample size of 354 school teachers in Malaysia. Multiple linear regression analysis has shown that teachers with high quality of teamwork and principal support were more likely to report innovative work behaviour. The findings indicated that teachers who frequently use humour can create more innovative behaviour. This paper can help managers and policymakers in the education sector, to develop a better understanding of these aspects, and their influence on teachers' innovative behaviour at work. In doing so, it would be helpful if teachers learnt effective procedures for innovative behaviour in class, via means of teamwork, humor, and principal support, to enhance their educational efforts. It is, therefore useful to establish university courses for pre-service teachers, focusing on new collaborative innovation strategies to encourage creativity and innovation in educational settings, and to apply collaborative creativity exercises in the classroom.

Keywords: Teamwork quality, Humor, Principal support, Teachers, Innovative work behavior, Malaysia
Conceptualising Higher Education Asianization: ASIANur
Authors: Kassim Mohd Azraai , Damio Siti Maftuhah , Omar Abdul Rahman 
Published: June 2021

Abstract: Higher Education (HE) plays an active role in nation building by developing and transforming the human capital holistically. This lifelong endeavour is by no means smooth sailing as HEs have to face many challenges. One prominent challenge is of university ranking, which is highly Westernized and exceedingly quantitative. “Creatical thinking” and “Asianization” concepts were thus forged in formulating “ASIANur”, an Asian university ranking. The justifications for ASIANur are based on Asian countries’ strength in relation to their economic, demographic, strength of HE as well as the emerging systematizing and standardizing of research disseminations. The possibility of Asian Higher Education Century is strengthen when ASIANur is materialised.

Keywords: Asianization, ASIANur, Creatical thinking, Higher education, Human capital.
COVID-Driven Innovation in Higher Education: Analysing the Collaboration of Leadership and Digital Technology during the Pandemic in UiTM Malaysia and UNNES Indonesia
Authors: Pramono Suwito Eko , Wijaya Atika , Melati Inaya Sari , Sahudin Zahariah , Abdullah Hasni 
Published: June 2021

Abstract: This study aims to analyse the way leadership and digital technology usage affect the faculty members’ research performance in surviving higher education sustainability during the COVID-19 pandemic. A breakthrough innovation is needed to design a fast-track online work management system. Hence, it requires a loyal contribution from all the faculty members to support this system. This quantitative study conducted in Malaysia and Indonesia, included 260 faculty members from various fields of studies. Using the online questionnaire, it shows that leadership and technology usage plays an important role to maintain faculty members’ research performance during the pandemic. However, it has a slight difference in result between Malaysia and Indonesia in terms of the portion of leadership and digital technology that affected the research performance. The higher education leaders play a stronger role in affecting Malaysian faculty members’ research performance, while Indonesian faculty members are influenced more by digital technology usage than by their leaders. Each of them has a significant implication in designing the effective institution policies in optimizing faculty members’ research performance.

Keywords: COVID-19, research performance, leadership, digital technology
A influência do desenvolvimento de planos de aula transdisciplinares no contexto da tecnologia digital para a transformação da compreensão de docência
Authors: Lima Luciana de , Loureiro Robson Carlos 
Published: June 2021

O objetivo da pesquisa é analisar de que forma os licenciandos que frequentam a disciplina Tecnodocência no segundo semestre de 2018 transformam a compreensão de docência ao desenvolver planos de aula transdisciplinares com inserção de tecnologias digitais. Diante do problema da fragmentação dos saberes na formação de licenciandos e da subutilização das Tecnologias Digitais da Informação e Comunicação (TDICs) em seu currículo formativo, fundamenta-se a pesquisa com base na Transdisciplinaridade. A pesquisa qualitativa, pautada em Estudo de Caso, apresenta como unidade de análise dois grupos transdisciplinares de cursos de Licenciatura participantes da disciplina ofertada por Instituição Pública de Ensino Superior (IPES). Subdivide-se em três etapas: preparação dos instrumentos e equipamentos de coleta e análise de dados; verificação dos conhecimentos prévios dos licenciandos e posterior investigação do desenvolvimento dos planos de aula; e, análise interpretativa dos dados. Constataram-se indícios de transformação em relação à centralização da ação docente, ao desenvolvimento didático-metodológico e ao uso das tecnologias digitais ao elaborarem planos de aula pautados nos pressupostos transdisciplinares em conjunto com as TDICs. Pretende-se dar prosseguimento à pesquisa em semestres subsequentes para investigação dessa mesma problemática com diferentes grupos de licenciandos.
O DIREITO PENAL NA QUARTA REVOLUÇÃO INDUSTRIAL
Authors: De Lima Filho Paulo Roberto Aguiar 
Published: June 2021

Resumo
A Quarta Revolução Industrial é uma realidade, ainda que a maioria das pessoas não se dê conta disso. Cada vez mais, informatizamos a vida humana, originando-se uma fertilidade nunca antes vista para a atuação criminosa por meio da tecnologia da informação ou contra esta. O presente trabalho busca inserir o Direito Penal no contexto da Revolução 4.0, abordando alguns pressupostos fundamentais, como as ideias de bem jurídico e sua exclusiva proteção, bem como a de expansão razoável do Direito Penal a partir da concepção de tecnologia da informação como bem importantíssimo à sociedade que requer proteção jurídico-penal. Levando-se isso em consideração, trata-se de abordar o tema dos crimes cibernéticos, analisando-se a possível existência de uma deficiência da legislação penal, para tanto sendo tomadas como parâmetros a Convenção de Budapeste e a CPI dos Crimes Cibernéticos.

Abstract
The Fourth Industrial Revolution is a reality, even though most people don't realize it. Increasingly, we informatize human life, giving birth to a fertility never before seen in respect to the criminal activity through information technology or against it. The present work aims to insert Criminal Law in the context of the Industry 4.0, addressing some fundamental assumptions, such as protected legal interest and its exclusive protection, as well as the reasonable expansion of Criminal Law, from the conception of information technology as a very important asset for the society, requiring legal-penal protection. Taking this into account, the work deals with addressing the theme of cybercrimes, analyzing the possible existence of a deficiency in the brazilian Criminal Law, taken the Budapest Convention and the brazilian Parliamentary Inquiry Commission on Cybercrimes as parameters.
PEMBINAAN TEKNOLOGI PETANI DALAM PENGEMBANGAN ANEKA PRODUK TEMBAKAU NON ROKOK: LANGKAH MAJU KABUPATEN BANDUNG
Authors: Trimo Lucyana , Hidayat Syarif 
Published: June 2021

Industri rokok tidak kalah penting pengaruhnya terhadap perekonomian Indonesia yaitu, telah memberikan kontribusi yang cukup besar baik dari tenaga kerja maupun pendapatan negara melalui cukai. Adanya FCTC (Framework Convention on Tobacco Control) menyebabkan industri rokok mengalami tekanan publik yang sangat kuat, terutama dikaitkan dengan pencanangan agenda global Hari Kesehatan Sedunia. Ini berdampak terhadap petani tembakau sebagai pemasok bahan baku olahan rokok, banyak petani tembakau yang pada akhirnya mengganti tanamannya dengan tanaman lain yang memiliki nilai kurang ekonomis dibandingkan tanaman tembakau. Untuk mengantisipasiÂ dampak FCTC tersebut, perlu ada inovasi teknologi dalam aneka produk olahan tembakau non rokok. Beberapa aneka produk olahan tembakau non rokok, adalah: pupuk, pestisida, farmasi, cat untuk batik, briket, minyak tembakau,dan lain-lain yang memiliki nilai tambah Â lebih tinggi dibandingkan dalam bentuk rokok. Metode penelitian yang digunakan adalah survey dengan pendekatan kuantitaif deskriptif . Responden (petani tembakau) diambil di lima Kecamatan Â pada Kabupaten Bandung, yang memiliki potensi besar untuk komoditas tembakau, dan merupakan salah satu sentra produksi tembakau setelah kabupaten Garut Â di Jawa Barat. Kelima wilayah penelitian Â ini merupakan wilayah binaan dari Disperindag Kabupaten Bandung dalam mengembangkan produk olahan tembakau non rokok. Â Wawancara juga dilakukan terhadap Informan, yaitu: ketua dan pengurus Kelompok Tani Tembakau, Asosiasi Tembakau Indonesia, staf instansi terkait (Disperidag), dan tokoh masyarakat di wilayah penelitian. Teknik FGD juga dilakukan. Data hasil penelitian ditabulasikan, dideskripsikan dan dianalisis melalui pendekatan system thinking. Hasil penelitian menunjukan, masih banyak kendala dalam mengembangkan agroindustriÂ produk tembakau non rokok, dan model pengembangannya harus dibangun secara terintegrasi dan Â menyeluruh, karena terkait dengan berbagai stakeholder.
contato do português com as línguas indígenas brasileiras: Considerações sobre o desenvolvimento de L2
Authors: Dos Santos Peixoto Jaqueline 
Published: June 2021

Nosso objetivo neste artigo é contar uma parte da história do português do Brasil a partir do contato com as línguas indígenas nacionais. Para realizar esse objetivo, buscamos trabalhos que versam sobre a presença real de características gramaticais e sonoras das línguas dos povos indígenas no português falado pelos membros desses povos. A interferência das gramáticas nativas dos povos indígenas é discutida a partir de propriedades sonoras consonantais e vocálicas do Português Ticuna (BONIFÁCIO, 2019); de propriedades consonantais do Português Kamaiurá (SILVA E SILVA, 1985); de propriedades gramaticais dos subsistemas da flexão de número no nome e da flexão de primeira e terceira pessoa do plural no verbo do Português Xinguano (EMMERICH, 1987); e de características gramaticais da expressão do gênero no português Huni Kuin (CHRISTINO, 2015). Defendemos que compreender o conhecimento linguístico responsável por produzir as características do português de contato com as línguas indígenas brasileiras possa esclarecer fenômenos envolvidos no processo de bilinguismo/multilinguismo dos povos indígenas, e ajudar a lidar com os desafios da educação escolar indígena. Para explicar o comportamento linguístico e mostrar como ele se apoia nas propriedades da Faculdade da Linguagem recorremos ao conceito de interlíngua (SELINKER, 1972). Partindo desse conceito, o início do processo de conhecimento de L2 seria marcado pela presença da gramática nativa e pelos dados da segunda língua. Todo esse processo seria restringido pelas propriedades gerais e abstratas da linguagem humana (WHITE, 2003). Assim, demonstramos como gramáticas nativas estruturam o português de contato. Pretendemos com reconhecimento dessa estruturação um resgate da participação da língua e cultura dos povos nativos na sociedade brasileira, e uma promoção do seu processo de descolonização.
Subjetividade e Formas de Vida em Foucault
Authors: Pimentel Figueira Anastacio Lara 
Published: June 2021

O artigo pretende mostrar que a noção foucaultiana de “subjetividade”, que aparece principalmente em suas genealogias da década de 80 dedicadas Ã s técnicas de si na antiguidade, também compõe uma crítica da razão governamental ao interpretar os modos de subjetivação dos antigos como modelo de governo de si. Após abordamos a questão em O uso dos prazeres, analisaremos o exemplo da escrita de si como produção de subjetividade dos antigos para argumentarmos que, no pensamento de Foucault, a noção de subjetividade está necessariamente vinculada Ã criação de formas de vida ou de um governo das próprias condutas. Em outros termos, certa disposição da relação entre sujeito e verdade corresponde a uma direção que Foucault identifica como ética.
Passagem e Progresso na Antropologia de Kant
Authors: Braga Junior Antonio Djalma 
Published: June 2021

Esse artigo tem como objetivo analisar como a antropologia pode representar um modo de realização da passagem entre liberdade e natureza no pensamento de Kant. Assim, pretendemos deixar claro que o problema inaugurado nas introduções Ã Crítica da Faculdade de Julgar, sobre a possibilidade de uma passagem entre o abismo aparentemente intransponível da liberdade e da natureza se torna possível não apenas a partir das reflexões realizadas sobre a faculdade de julgar e suas implicações nos juízos de gosto sobre o belo e nos juízos de finalidade, mas, também, a partir da tese do progresso presente na filosofia da história de Kant que recebe uma de suas formas de realização nas questões que envolvem a natureza humana (antropologia).