bluuebunny/crossref_metadata_2025_split huggingface dataset:
Introducing Nanoclay and Silica-based Composites as a New Approach for
Improving Chemical and Mechanical Properties of Soil: A Review
Authors: Haddad Abdolhosein , Karimi-Maleh Hassan , Dehestani Hojat 
Published: October 2021

:
Layered silicates (nanoclay) are new types of nanomaterials derived from clay minerals with a
wide range of applications in different fields such as catalysts, soil industry, etc. Nanoclays are wide
ranges of naturally occurring inorganic minerals with different derivatives. Montmorillonite is a wellknown
nanoclay consisting of a 2:1 layered structure with two-silica tetrahedron sandwiching an alumina
octahedron. In nature, nanoclays can be found in both crystalline (phyllosilicates) and non-crystalline
(imogolite) forms. Nanoclays incorporated into polymer matrices have demonstrated a significant capability
to improve the tensile and barrier properties of soil. Nanoclays play a vital role in enhancing soil quality
due to their high surface area and porous structure. On the other hand, due to the positive charge of
sand grains and the chemical compositions of clay particles, the negatively charged clay particles help
create a good condition to improve soil properties. According to the best of our knowledge, there is no
review paper to study the role of nanoclays on soil samples. This review paper describes the role of
nanoclay compounds in the improved properties of soil samples and introduces different types of modified
nanoclay used in soil samples. Reported results showed that nanoclays with complex structures are
useful nanomaterials for improving the quality of soil samples.
THE ROLE OF BETA-BLOCKERS IN VETIANGINAL THERAPY IN THE CORRECTION OF VIOLATIONS OF THE AMINO ACID SPECTRUM IN PATIENTS WITH UNSTABLE ANGINA WITH CONCOMITANT DIABETES MELLITUS
Authors: Bohdan Tetiana , Lizogub Viktor , Sobol Viktoriia , Bohdan Viktor 
Published: October 2021

The purpose of the study: to study the effect of bisoprolol and nebivolol on the spectrum of essential blood plasma AK in patients with concomitant diabetes mellitus (DM) type 2 in order to optimize drug treatment of this pathology in the future.Material and methods. The study involved 70 patients with NA with concomitant DM type 2, which was divided into two groups: group I (37 patients) as part of basic antianginal therapy received bisoprolol, group II (33 patients) received nebivolol. The control group (CG) consisted of 18 healthy individuals. All patients were tested for irreplaceable blood plasma AA by ion exchange liquid chromatography on an automatic analyzer AK T-339 produced by «Microtechna» (Czech Republic, Prague) at the Institute of Biochemistry named after OV Palladin NAMS of Ukraine. The following essential AAs were identified: arginine, valine, histidine, isoleucine, leucine, lysine, methionine, threonine, phenylalanine. Examination of patients was performed at the beginning of treatment and after 20 days. Results. It was determined that in patients with NA with concomitant DM type 2 under the influence of antianginal therapy in both groups significantly decreased the total amount of irreplaceable AA compared with control group, indicating an increase in intracellular metabolism as a compensatory response in coronary circulation. It should be noted that in patients of group II, in contrast to patients of group I, under the influence of treatment the level of histidine remained normal. The level of threonine significantly decreased compared to CG and the rate of patients in group I, the level of valine significantly increased compared to pre-treatment, the level of isoleucine significantly decreased compared with CG and with the rate of patients of group I. Importantly, ammonia levels returned to normal under the influence of basic therapy, which included nebivolol.Conclusion. The dynamics of changes in the levels of individual irreplaceable AA blood plasma, due to the mechanisms of their metabolic transformations in patients with NA with concomitant DM type 2 indicates greater effectiveness of nebivolol and the feasibility of its prescription іn complex of a basic antianginal therapy.
Vitamin D, Testosterone, and Thyroid Status in Young Men at Different Seasons
Authors: Bondarenko Vladimir , Goncharova Olga , Minukhin Andriy , Skornyakov Evgeniy 
Published: October 2021

There are evidences that seasonal fluctuations in vitamin D levels coincide with annual rhythms of testosterone levels, and hypothyroidism may be a predictor of hypoandrogenism.
The aim of the study was to establish the levels of vitamin D (vit. D), testosterone (T), thyroid stimulating hormone (TSH) and free thyroxine (T4f) in young people with pathospermia and normospermia in the spring-summer and autumn-winter periods.
Materials and methods. The data of 58 men aged 23-44 years, who are in a sterile marriage, were analyzed: 24 were examined in the spring-summer period, 34 - in the autumn-winter period. BMI, levels of T, TSH, T4fandvit. Dwere investigated.
Results. In the general group of men, the frequency of D - hypovitaminosis was higher in those examined in the autumn-winter period. Vit D levels were significantly lower with pathospermia than with normospermia. BMI did not significantly affect the level of vit.D in the blood.A direct correlation between vit. D and T in men with patho- and normospermiahas not been established, although such a correlation took place in the general group of the surveyed.
The average TSH values ​​in the group examined in the spring-summer period did not significantly differ in the group with patho- and normospermia, and in those examined in the autumn-winter period, against the background of pathospermia, there was a decrease in T4f values ​​and an increase in TSH. 13.6% of this subgroup had laboratory signs of subclinical hypothyroidism.
Conclusions:

In men of the general group, without taking into account the state of the spermatogenic function of the testicles, examined in the autumn-winter period, there is a significant increase in the frequency of D-hypovitaminosis compared with a similar group of men in whom the level of vitamin D blood was determined in the spring-summer period.
Regardless of the examination period, patients with pathospermia show a decrease in the average levels of vitamin D and testosterone compared to men with normal semen parameters.
The frequency of vitamin D deficiency in patients with pathospermia significantly increases in the autumn-winter period.

Disorders of spermatogenesis in men can be associated with the hypofunctional state of the thyroid gland against the background of the existing deficiency of vitamin D in the autumn-winter period.
Anais da XLI Semana Médica da Faculdade de Medicina de Itajubá
Authors: XLI Semana Médica da FMIT  
Published: October 2021

A Semana Médica é um tradicional congresso médico-acadêmico realizado na Faculdade de Medicina de Itajubá, organizado pela coordenadoria de Educação Médica do Diretório Acadêmico 8 de Outubro. Neste ano, em sua 41ª edição, serão novamente oferecidas oportunidades únicas de prestigiar renomados palestrantes e apresentar trabalhos de iniciação científica. Nosso compromisso com a divulgação da ciência de qualidade prioriza temas atuais de interesse a acadêmicos e profissionais de toda a área da saúde.
Characteristics of Participants and Nonparticipants in a Blended Internet-Based Physical Activity Trial for Breast and Prostate Cancer Survivors: Cross-sectional Study
Authors: vd Wiel Hester J , Stuiver Martijn M , May Anne M , van Grinsven Susan , Benink Marlou F A , Aaronson Neil K , Oldenburg Hester S A , van der Poel Henk G , van Harten Wim H , Groen Wim G 
Published: October 2021

Background
As the number of cancer survivors is increasing, it is important to be able to offer exercise and physical activity (PA)–promoting interventions that are both effective and reasonably accessible. Internet-based interventions are typically less expensive and more accessible alternatives to on-site supervised interventions. Currently, little is known about the characteristics of nonparticipants in PA promotion trials in the cancer survivorship setting, both in general and specifically in trials using internet-supported interventions.

Objective
This study aims to gain insight into the characteristics associated with nonparticipation in a blended internet-based supported intervention trial to promote PA.

Methods
Breast and prostate cancer survivors, 3-36 months after primary curative treatment, were invited to participate in the PABLO trial; this trial compared an internet-based intervention to enhance PA levels, with or without additional support from a physical therapist, to usual care. Participants and nonparticipants were asked to complete a comprehensive questionnaire assessing sociodemographics, fatigue, and health-related quality of life. Baseline data for participants and nonparticipants were compared using the independent Student t test and chi-square test.

Results
The inclusion rate in the trial was 11.03% (137/1242). Of the nonparticipants, 13.95% (154/1104) completed the questionnaire. Participants were more highly educated (P=.04), had a paid job less often (P=.03), and were on sick leave more often (P=.03). They reported less PA per week, both moderate (P=.03) and vigorous (P<.01), before diagnosis and during leisure time (P<.01, effect size [ES]=0.44). They reported a significantly lower stage of change (P≤.01), lower self-efficacy (P<.01, ES=0.61), perceived barriers to PA (P<.01, ES=0.54), and more general fatigue (P<.01, ES=0.60). Participants reported lower health-related quality of life for most domains (ES ranging from 0.34 for mental health to 0.48 for social functioning). No significant differences were found for other sociodemographics, mood state, or attitudes toward or perceived social support for PA.

Conclusions
The participants who self-selected for trial participation reported lower PA levels before diagnosis and a stronger need for support compared with nonparticipants. The trial thus included those patients who might benefit the most from internet-based supportive PA interventions.

Trial Registration
Netherlands trial register NTR6911; https://www.trialregister.nl/trial/6733
FOCUS mHealth Intervention for Veterans With Serious Mental Illness in an Outpatient Department of Veterans Affairs Setting: Feasibility, Acceptability, and Usability Study
Authors: Buck Benjamin , Nguyen Janelle , Porter Shelan , Ben-Zeev Dror , Reger Greg M 
Published: October 2021

Background
Veterans with serious mental illnesses (SMIs) face barriers to accessing in-person evidence-based interventions that improve illness management. Mobile health (mHealth) has been demonstrated to be feasible, acceptable, effective, and engaging among individuals with SMIs in community mental health settings. mHealth for SMIs has not been tested within the Department of Veterans Affairs (VA).

Objective
This study examines the feasibility, acceptability, and preliminary effectiveness of an mHealth intervention for SMI in the context of VA outpatient care.

Methods
A total of 17 veterans with SMIs were enrolled in a 1-month pilot trial of FOCUS, a smartphone-based self-management intervention for SMI. At baseline and posttest, they completed measures examining symptoms and functional recovery. The participants provided qualitative feedback related to the usability and acceptability of the intervention.

Results
Veterans completed on an average of 85.0 (SD 96.1) interactions with FOCUS over the 1-month intervention period. They reported high satisfaction, usability, and acceptability, with nearly all participants (16/17, 94%) reporting that they would recommend the intervention to a fellow veteran. Clinicians consistently reported finding mHealth-related updates useful for informing their care. Qualitative feedback indicated that veterans thought mHealth complemented their existing VA services well and described potential opportunities to adapt FOCUS to specific subpopulations (eg, combat veterans) as well as specific delivery modalities (eg, groups). In the 1-month period, the participants experienced small improvements in self-assessed recovery, auditory hallucinations, and quality of life.

Conclusions
The FOCUS mHealth intervention is feasible, acceptable, and usable among veterans. Future work should develop and examine VA-specific implementation approaches of FOCUS for this population.
Electronic Monitoring Systems for Hand Hygiene: Systematic Review of Technology
Authors: Wang Chaofan , Jiang Weiwei , Yang Kangning , Yu Difeng , Newn Joshua , Sarsenbayeva Zhanna , Goncalves Jorge , Kostakos Vassilis 
Published: October 2021

Background
Hand hygiene is one of the most effective ways of preventing health care–associated infections and reducing their transmission. Owing to recent advances in sensing technologies, electronic hand hygiene monitoring systems have been integrated into the daily routines of health care workers to measure their hand hygiene compliance and quality.

Objective
This review aims to summarize the latest technologies adopted in electronic hand hygiene monitoring systems and discuss the capabilities and limitations of these systems.

Methods
A systematic search of PubMed, ACM Digital Library, and IEEE Xplore Digital Library was performed following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Studies were initially screened and assessed independently by the 2 authors, and disagreements between them were further summarized and resolved by discussion with the senior author.

Results
In total, 1035 publications were retrieved by the search queries; of the 1035 papers, 89 (8.60%) fulfilled the eligibility criteria and were retained for review. In summary, 73 studies used electronic monitoring systems to monitor hand hygiene compliance, including application-assisted direct observation (5/73, 7%), camera-assisted observation (10/73, 14%), sensor-assisted observation (29/73, 40%), and real-time locating system (32/73, 44%). A total of 21 studies evaluated hand hygiene quality, consisting of compliance with the World Health Organization 6-step hand hygiene techniques (14/21, 67%) and surface coverage or illumination reduction of fluorescent substances (7/21, 33%).

Conclusions
Electronic hand hygiene monitoring systems face issues of accuracy, data integration, privacy and confidentiality, usability, associated costs, and infrastructure improvements. Moreover, this review found that standardized measurement tools to evaluate system performance are lacking; thus, future research is needed to establish standardized metrics to measure system performance differences among electronic hand hygiene monitoring systems. Furthermore, with sensing technologies and algorithms continually advancing, more research is needed on their implementation to improve system performance and address other hand hygiene–related issues.
Transformation and Evaluation of the MIMIC Database in the OMOP Common Data Model: Development and Usability Study
Authors: Paris Nicolas , Lamer Antoine , Parrot Adrien 
Published: October 2021

Background
In the era of big data, the intensive care unit (ICU) is likely to benefit from real-time computer analysis and modeling based on close patient monitoring and electronic health record data. The Medical Information Mart for Intensive Care (MIMIC) is the first open access database in the ICU domain. Many studies have shown that common data models (CDMs) improve database searching by allowing code, tools, and experience to be shared. The Observational Medical Outcomes Partnership (OMOP) CDM is spreading all over the world.

Objective
The objective was to transform MIMIC into an OMOP database and to evaluate the benefits of this transformation for analysts.

Methods
We transformed MIMIC (version 1.4.21) into OMOP format (version 5.3.3.1) through semantic and structural mapping. The structural mapping aimed at moving the MIMIC data into the right place in OMOP, with some data transformations. The mapping was divided into 3 phases: conception, implementation, and evaluation. The conceptual mapping aimed at aligning the MIMIC local terminologies to OMOP's standard ones. It consisted of 3 phases: integration, alignment, and evaluation. A documented, tested, versioned, exemplified, and open repository was set up to support the transformation and improvement of the MIMIC community's source code. The resulting data set was evaluated over a 48-hour datathon.

Results
With an investment of 2 people for 500 hours, 64% of the data items of the 26 MIMIC tables were standardized into the OMOP CDM and 78% of the source concepts mapped to reference terminologies. The model proved its ability to support community contributions and was well received during the datathon, with 160 participants and 15,000 requests executed with a maximum duration of 1 minute.

Conclusions
The resulting MIMIC-OMOP data set is the first MIMIC-OMOP data set available free of charge with real disidentified data ready for replicable intensive care research. This approach can be generalized to any medical field.
Exploring Online Health Reviews to Monitor COVID-19 Public Health Responses in Alabama State Department of Corrections: Case Example
Authors: Valera Pamela , Carmona David , Malarkey Sarah , Sinangil Noah , Owens Madelyn , Lefebre Asia 
Published: October 2021

Background
COVID-19, caused by SARS-CoV-2, has devastated incarcerated people throughout the United States.

Objective
The purpose of this study was to test the feasibility and acceptability of a COVID-19 Health Review for Correctional Facilities.

Methods
The COVID-19 Health Review survey for the Department of Corrections was developed in Qualtrics to assess the following: (1) COVID-19 testing, (2) providing personal protective equipment, (3) vaccination procedures, (4) quarantine procedures, (5) COVID-19 mortality rates for inmates, (6) COVID-19 mortality rates for correctional officers and prison staff, (7) COVID-19 infection rates for inmates, (8) COVID-19 infection rates for correctional officers and prison staff, and (9) uptake of COVID-19 vaccines. The estimated time to review the Alabama State Department of Corrections COVID-19 responses on their website and complete the survey items was 45 minutes to 1 hour.

Results
Of the 21 participants who completed the COVID-19 Health Review for Correctional Facilities survey, 48% (n=10) identified as female, 43% (n=9) identified as male, and 10% (n=2) identified as transgender. For race, 29% (n=6) self-identified as Black or African American, 24% (n=5) Asian, 24% (n=5) White, 5% (n=1) Pacific Islander or Native Hawaiian, and 19% (n=4) Other. In addition, 5 respondents self-identified as returning citizens. For COVID-19 review questions, the majority concluded that information on personal protective equipment was “poor” and “very poor,” information on COVID-19 testing was “fair” and above, information on COVID-19 death/infection rates between inmates and staff was “good” and “very good,” and information on vaccinations was “good” and “very good.” There was a significant difference observed (P=.03) between nonreturning citizens and returning citizens regarding the health grade review with respect to available information on COVID-19 infection rates.

Conclusions
COVID-19 health reviews may provide an opportunity for the public to review the COVID-19 responses in correctional settings.
Cardiovascular Safety and Hemostatic Efficacy of Topical Epinephrine in Children Receiving Zirconia Crowns
Authors: Fazeli Afsoon , Nelson Travis M. , Fazeli Mir Sohail , Lin Yvonne S. , Scott JoAnna 
Published: October 2021

Objective:
The primary aim of this study was to determine the cardiovascular safety of topical racemic epinephrine pellets by measuring heart rate, systolic blood pressure, diastolic blood pressure, and mean arterial pressure in children receiving dental care under general anesthesia. The secondary aim was to assess clinical efficacy by measuring time to reach adequate hemostasis.

Methods:
For this pilot study utilizing a split-mouth randomized design, 13 patients requiring prefabricated zirconia crowns on both primary maxillary first molars were recruited. Patients received continuous infusions of propofol and remifentanil with 50–70% inhaled nitrous oxide and oxygen. After randomization and tooth preparation, either saline pellets (control) or racemic epinephrine pellets (experimental) were applied directly to gingival tissue. Vital signs were recorded for 5 minutes. The procedure was repeated on the contralateral side using the alternative (control or experimental) treatment.

Results:
Topical racemic epinephrine compared to saline produced a significantly larger decrease in mean diastolic blood pressure (−11.1% vs −3.9%; P &lt; .01) and mean arterial pressure (−8.1% vs −2.1%; P &lt; .01), although all noted decreases in cardiovascular variables were clinically insignificant. All experimental treatment teeth achieved adequate hemostasis after 2.2 minutes. Only 5 of the 13 control treatment teeth achieved adequate hemostasis during the 5-minute observation period (1.6 vs 4.2 minutes; P = .01).

Conclusion:
Overall, we conclude that use of topical racemic epinephrine pellets did not result in adverse cardiovascular effects and hemostasis was reached more quickly and predictably compared to saline pellets.
Effect of Feeding Rate on Survival, Zootechnical Performance of Tilapia Oreochromis niloticus (Linnaeus, 1758) Brazil Strain Larvae Fed on 17-α-methyltestosterone Treated Feed
Authors: Ouattara Issa Nahoua , Zea Bi Ue Claver , Berte Siaka , Kamagate Bakagnan 
Published: October 2021

This study was conducted to evaluate the feeding levels on survival, growth performance and feed utilization in the Brazil strain of Nile tilapia Oreochromis niloticus. Four (4) batches of larvae with mean initial weight 0.012 ± 0.005 g and mean initial total length 9 ± 0.003 mm were formed in triplicate, three per feeding rate. The rationing rates according to fry biomass applied in this trial were: batch 1: 50, 40, 30 and 25%, batch 2: 40, 30, 25 and 20%, batch 3: 30, 25, 20 and 18% and batch 4: 25, 20, 18 and 15% of biomass. The different feeding rates were tested during the 1st, 2nd, 3rd and 4th week of larval rearing respectively. The fish were all fed a commercial feed (48% protein) distributed manually at a frequency of 5 meals per day. After 28 days of rearing, the results show that apart from the survival rate, the other parameters such as final average weight, daily growth and food consumption index were affected by the different rationing rates tested. The larvae of batch 2 rationed at 40, 30, 25 and 20 % of their biomass during the 1st, 2nd, 3rd and 4th week of rearing respectively recorded significantly higher growth parameters (MWF: 1.092±0.027 g and DG: 0.038±0.000 g) and a more interesting food converion ratio (0.88 ) than the other batches of fry. From this study, it is concluded that an optimal feeding rate of 40, 30, 25 and 20% of the larval biomass during the 1st, 2nd, 3rd and 4th week of rearing, respectively, should be applied in order to avoid either wastage or underfeeding of the subjects during hormone treatment with 17 α-methyltestosterone.