bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perspectives on the development and future of oocyte IVM in clinical practice
Authors: De Vos Michel , Grynberg Michaël , Ho Tuong M. , Yuan Ye , Albertini David F. , Gilchrist Robert B. 
Published: July 2021

AbstractOocyte in vitro maturation (IVM) is an assisted reproductive technology designed to obtain mature oocytes following culture of immature cumulus–oocyte complexes collected from antral follicles. Although IVM has been practiced for decades and is no longer considered experimental, the uptake of IVM in clinical practice is currently limited. The purpose of this review is to ensure reproductive medicine professionals understand the appropriate use of IVM drawn from the best available evidence supporting its clinical potential and safety in selected patient groups. This group of scientists and fertility specialists, with expertise in IVM in the ART laboratory and/or clinic, explore here the development of IVM towards acquisition of a non-experimental status and, in addition, critically appraise the current and future role of IVM in human ART.
Differences in Perceived and Experienced Stigma Between Problematic Gamblers and Non-gamblers in a General Population Survey
Authors: Andrà Chiara , Priolo Gabriele , Merlin Francesca , Chiavarino Claudia 
Published: July 2021

AbstractWe consider a sample of about 700 people, interviewed on the streets, who are sorted into two groups by a self-report, screening questionnaire: namely, non-problematic gamblers/non-gamblers and problematic gamblers. Within each group, we compare both social (perceived) stigma and self-perceived (experienced) stigma, measured by means of other two self-report questionnaires, and we seek for relations between stigma and socio-demographic variables that can help targeting possible interventions to reduce gambling-related stigma. We, then, compare stigma between the two groups of non-(problematic) gamblers and problematic ones, and we also check the hypothesis that higher social stigma is related to higher self-perceived stigma, as well as higher stigma is related to lesser help-seeking. The latter hypothesis is of utmost importance, given that stigma is recognised to be one of the major causes for hindering help-seeking by problematic gamblers. The research is carried out in Italy, one of the first countries in the world for the money spent per capita in gambling activity every year.
In the Region of Middle Axioms: Judicial Dialogue as Wide Reflective Equilibrium and Mid-level Principles
Authors: Moreso José Juan , Valentini Chiara 
Published: July 2021

AbstractThis article addresses the use of foreign law in constitutional adjudication. We draw on the ideas of wide reflective equilibrium and public reason in order to defend an engagement model of comparative adjudication. According to this model, the judicial use of foreign law is justified if it proceeds by testing and mutually adjusting the principles and rulings of our constitutional doctrines against reasonable alternatives, as represented by the principles and rulings of other reasonable doctrines. By this, a court points to a wide reflective equilibrium, justifying its own interpretations with reasonable arguments, i.e. arguments that are acceptable from the perspectives defined by other constitutional doctrines, as endorsed by other courts. The point of a judicial engagement of this sort is to work out an overlap between different, reasonable, doctrines in the judicial forum, as part of a liberal forum of public reason. Here, the exercise of public reason filters out the premises of comprehensive doctrines so as to leave us in the region of an overlapping consensus: a region of mid-level principles that can be shared, notwithstanding the fact of legal pluralism.
A type III porous-thermo-elastic problem with quasi-static microvoids
Authors: Bazarra Noelia , Castejón Alberto , Fernández José R. , Quintanilla Ramón 
Published: July 2021

AbstractIn this work we study, from the numerical point of view, a one-dimensional thermoelastic problem where the thermal law is of type III. Quasi-static microvoids are also assumed within the model. The variational formulation leads to a coupled linear system made of variational equations and it is written in terms of the velocity, the volume fraction and the temperature. Fully discrete approximations are introduced by using the finite element method and the backward Euler method. A discrete stability property and a priori error estimates are proved, deriving the linear convergence under adequate additional regularity. Finally, some numerical simulations are presented to demonstrate the accuracy of the approximation and the behavior of the solution.
No-arbitrage concepts in topological vector lattices
Authors: Platen Eckhard , Tappe Stefan 
Published: July 2021

AbstractWe provide a general framework for no-arbitrage concepts in topological vector lattices, which covers many of the well-known no-arbitrage concepts as particular cases. The main structural condition we impose is that the outcomes of trading strategies with initial wealth zero and those with positive initial wealth have the structure of a convex cone. As one consequence of our approach, the concepts NUPBR, NAA$$_1$$1and NA$$_1$$1may fail to be equivalent in our general setting. Furthermore, we derive abstract versions of the fundamental theorem of asset pricing (FTAP), including an abstract FTAP on Banach function spaces, and investigate when the FTAP is warranted in its classical form with a separating measure. We also consider a financial market with semimartingales which does not need to have a numéraire, and derive results which show the links between the no-arbitrage concepts by only using the theory of topological vector lattices and well-known results from stochastic analysis in a sequence of short proofs.
On glasses half full or half empty: understanding framing effects in terms of default implicatures
Authors: Caamaño-Alegre María 
Published: July 2021

AbstractThe variations in how subjects respond to positively or negatively framed descriptions of the same issue have received attention from social science research, where, nevertheless, a naïve understanding of speech interpretation has undermined the different explanations offered. The present paper explores the semantic-pragmatic side of framing effects and provides a unifying explanation of this phenomenon in terms of a combined effect of pragmatic presuppositions and default implicatures. The paper contributes to a more comprehensive understanding of representations and cognitive processes involved in the framing bias by showing how well-entrenched linguistic practices associated to frame choice, and conducive to an implicit focus, result in default implicatures on the addressee’s side.
Making a difference in virtue epistemology
Authors: Hundertmark Fabian , Kindley Steven 
Published: July 2021

AbstractVirtue Reliabilism holds that knowledge is a cognitive achievement—an epistemic success that is creditable to the cognitive abilities of the knowing subject. Beyond this consensus, there is much disagreement amongst proponents of virtue reliabilism about the conditions under which the credit-relation between an epistemic success and a person’s cognitive abilities holds. This paper aims to establish a new and attractive view of this crucial relation in terms of difference-making. We will argue that the resulting theory, Difference-Making Virtue Epistemology, can deal with cases of epistemic luck and testimonial knowledge while revealing the common core of knowledge and other achievements.
Reflexivity Without Noticing: Durand of Saint-Pourçain, Walter Chatton, Brentano
Authors: Girard Charles 
Published: July 2021

AbstractAccording to Franz Brentano, every mental act includes a representation of itself. Hence, Brentano can be described as maintaining that: (T1) reflexivity, when it occurs, is included as a part in mental acts; and (T2) reflexivity always occurs. Brentano’s way of understanding the inclusion of reflexivity in mental acts (T1) entails double intentionality in mental acts. The aim of this paper is to show that the conjunction of (T1) and (T2) is not uncommon in the history of philosophy. To that end, the theories of two medieval thinkers, namely, Walter Chatton and Durand of Saint-Pourçain, are presented. The repeated conjunction of (T1) and (T2) paves the way for a more general distinction than that between subjectivist and objectivist theories of reflexivity, namely, one between automatic theories of reflexivity (where noticing is not required for reflexivity) and apperceptive theories of reflexivity (where noticing is required for reflexivity).
Predictive factors for refractory stage I and II anti-resorptive agent-related osteonecrosis of the jaw
Authors: Shimizu Takahiro , Kim Mai , Dam Trang Thuy , Kurihara Jun , Ogawa Masaru , Makiguchi Takaya , Yokoo Satoshi 
Published: July 2021

Abstract
Objectives
We aimed to predict the possibility of patients with stage I and II anti-resorptive agent-related osteonecrosis of the jaw (ARONJ) developing resistance to our treatment protocol by evaluating their clinical and imaging factors.

Materials and methods
We enrolled 58 patients with ARONJ who underwent imaging modality. As objective variables, we considered the healing, stage-down, and stable stages as successful outcomes, and the stage-up stage as resistant-to-treatment. As explanatory variables, we investigated the clinical and imaging factors. Furthermore, we examined stage-down as an improvement outcome to compare with the stable and stage-up stages, which were considered as no-improvement outcomes. We conducted unpaired between-group comparisons on all explanatory variables using χ2 tests for independence.

Results
Among 58 patients, the treatment was successful in 53 (91.4%); however, the disease was resistant in five (8.6%). Among the clinical factors, the resistant patients had a longer duration of administration of bone-modifying agents (BMAs) (cut-off: 1251 days, p = 0.032, odds ratio = 11.2, 95% confidence interval 1.115–122.518). In addition, the target disease that was being treated bone metastasis of malignant tumor was the only significant refractory factor (p = 0.024, OR: 3.667 95% CI 1.159–11.603)

Conclusions
A combination of metabolic and morphological imaging modalities may be useful for oral surgeons to evaluate the disease activity and predict course of refractory ARONJ.
Cognition and behavior in context: a framework and theories to explain natural resource use decisions in social-ecological systems
Authors: Constantino S. M. , Schlüter M. , Weber E. U. , Wijermans N. 
Published: July 2021

AbstractThe complex, context-dependent, and dynamic nature of human behavior is increasingly recognized as both an important cause of sustainability problems and potential leverage for their solution. Human beings are diverse, as are the social, ecological, and institutional settings in which they are embedded. Despite this recognition and extensive knowledge about human decision-making in the behavioral sciences, empirical analysis, formal models, and decision support for sustainability policy in natural resource management often either neglect human behavior or are based on narrow and overly simplistic assumptions. Integrating insights from behavioral sciences into sustainability research and policy remains a challenge. This is in part due to the abundance and fragmentation of theories across the social sciences and in part the challenges of translating research across disciplines. We provide a set of tools to support the integration of knowledge about human behavior into empirical and model-based sustainability research. In particular, we (i) develop a process-oriented framework of embedded human cognition (Human Behavior-Cognition in Context or HuB-CC), (ii) select an initial set of 31 theories with the potential to illuminate behavior in natural resource contexts and map them onto the framework, and (iii) suggest pathways for using the framework and mapping to encourage trans-disciplinary investigations, identify and compare theories, and facilitate their integration into empirical research, formal models, and ultimately policy and governance for sustainability. Our theory selection, framework, and mapping offer a foundation—a “living” platform—upon which future collaborative efforts can build to create a resource for scholars and practitioners working at the intersection of social sciences and natural resource management.
Knowing Falsely: the Non-factive Project
Authors: Bricker Adam Michael 
Published: July 2021

AbstractQuite likely the most sacrosanct principle in epistemology, it is near-universally accepted that knowledge is factive: knowing that p entails p. Recently, however, Bricker, Buckwalter, and Turri have all argued that we can and often do know approximations that are strictly speaking false. My goal with this paper is to advance this nascent non-factive project in two key ways. First, I provide a critical review of these recent arguments against the factivity of knowledge, allowing us to observe that elements of these arguments mutually reinforce respective weaknesses, thereby offering the non-factive project a much stronger foundation than when these arguments were isolated. Next, I argue tentatively in favor of Bricker’s truthlikeness framework over the representational adequacy account favored by Buckwalter and Turri. Taken together, while none of this constitutes a knock-down argument against factivity, it does allow us to quiet some of the more immediate worries surrounding the non-factive project.
Perceptions of Sexual Healthcare Provision in Tanzania: a Key Informant Qualitative Study
Authors: Mgopa Lucy R. , Ross Michael W. , Lukumay Gift Gadiel , Mushy Stella Emmanuel , Mkony Ever , Massae Agnes F. , Mwakawanga Dorkas L. , Leshabari Sebalda , Mohamed Inari , Trent Maria , Wadley James , Bonilla Zobeida E. , Rosser B. R. Simon 
Published: July 2021

AbstractIntroductionSexual health care services must be standard and unbiased, guided by a structured health care system. There is a scarcity of data on how sexual health care is delivered in Tanzania.MethodsTo address this gap, in July 2019 we interviewed eleven key informants: cultural and public health experts, and political, religious, and community leaders, selected from different organizations in Dar es Salaam, Tanzania. Participants were asked for their opinions about clinical practices of health care professionals when providing care to patients, with an emphasis on sexual health.ResultsParticipants’ responses were classified into three subcategories: strengths, barriers, and gaps in sexual health care. Availability of services, service delivery to adults, and code of conduct were among the strengths observed in clinical care services. Barriers included the health care provider’s attitudes, moral values, and inadequacy in health policies and treatment guidelines. Vulnerable populations including youth were frequently reported to face most challenges when seeking sexual health care services. In terms of gaps, informants emphasized gender equity in sexual health services provision within care settings.Conclusion and ImplicationData indicate that lack of training in sexual health and guidelines for dealing with sexual issues are a barrier to comprehensive health care. These findings can inform the main areas for curriculum developers to focus on, when developing an Afro-centric sexual health curriculum suitable for students in health care professional courses. Moreover, these findings can be useful when developing treatment guidelines and policies that are beneficial to the sexual health wellbeing of individuals.
Embedding eddy current sensors into LPBF components for structural health monitoring
Authors: Stoll Philipp , Gasparin Enrico , Spierings Adriaan , Wegener Konrad 
Published: July 2021

AbstractLaser powder bed fusion (LPBF) facilitates the integration of external elements like sensors into workpieces during manufacturing. These embedded components enable e.g. part monitoring, thus being a fundamental application of industry 4.0. This study assesses the feasibility of embedding eddy current (EC) sensors for non-destructive testing (NDT) into SLM components aiming at structural health monitoring (SHM). A reliable embedding process for EC sensors is developed, ensuring the survivability of the sensors for the LPBF process and its harsh conditions. The experiments conducted demonstrate the possibility to use the embedded EC sensor to observe and detect a controlled crack growth. The cracks are realized either with direct EDM cutting or on the course of a fatigue test of CT specimens. The data retrieved by the embedded EC sensors are proven to provide a direct information about the severity of a damage and its evolution over time for both approaches. Thus, supporting the validation of such an innovative and promising SHM concept.
ECMO Therapy in Acute Chest Syndrome for Patients with Sickle Cell Disease: a Case Report and Literature Review
Authors: Avgeridou Soi , Djordjevic Ilija , Sabashnikov Anton , Eghbalzadeh Kaveh , Suhr Laura , Ivanov Borko , Merkle Julia , Rustenbach Christian , Mader Navid , Kröner Axel , Wahlers Thorsten 
Published: July 2021

AbstractExtracorporeal membrane oxygenation (ECMO) plays an important role as a life-saving tool for patients with therapy-refractory cardio-respiratory failure. Especially, for rare and infrequent indications, scientific data is scarce. The conducted paper focuses primarily on our institutional experience with a 19-year-old patient suffering an acute chest syndrome, a pathognomonic pulmonary condition presented by patients with sickle cell disease. After implementation of awake ECMO therapy, the patient was successfully weaned off support and discharged home 22 days after initiation of the extracorporeal circulation. In addition to limited data and current literature, further and larger data sets are necessary to determine the outcome after ECMO therapy for this rare indication.
REVA as A Well-Curated Database for Human Expression-Modulating Variants
Authors: Wang Yu , Shi Fang-Yuan , Liang Yu , Gao Ge 
Published: July 2021

Abstract
More than 90% of disease- and trait-associated human variants are noncoding. By systematically screening multiple large-scale studies, we compiled REVA, a manually curated database for over 11.8 million experimentally tested noncoding variants with expression-modulating potentials. We provided 2424 functional annotations that could be used to pinpoint the plausible regulatory mechanism of these variants. We further benchmarked multiple state-of-the-art computational tools and found that their limited sensitivity remains a serious challenge for effective large-scale analysis. REVA provides high-quality experimentally tested expression-modulating variants with extensive functional annotations, which will be useful for users in the noncoding variant community. REVA is freely available at http://reva.gao-lab.org.
Significance of Northern Andes Terrane Extrusion and Genesis of the Interandean Valley: Paleomagnetic Evidence From the “Ecuadorian Orocline”
Authors: Siravo Gaia , Speranza Fabio , Mulas Maurizio , Costanzo‐Alvarez Vincenzo 
Published: July 2021

AbstractGPS data suggest that the NW South America corner forms a semi‐rigid block drifting NE‐ward along the regional dextral strike‐slip faults that bound an oceanic terrane accreted in Late Cretaceous times to W Ecuador and Colombia. However, the relevance of both strike‐slip versus thrust tectonics during Cenozoic times and their relation with oceanic terrane accretion are unclear. Here we report on the paleomagnetism of 31 mid‐upper Eocene to upper Miocene mainly volcanic sites from the Cordilleras Occidental and Real of southern Ecuador. Eleven sites show that the western Cordillera Occidental underwent a 24° ± 10° clockwise (CW) rotation with respect to South America after late Miocene times, while no rotation occurred further east. We relate the regional CW rotation to the emplacement of the Cordillera Occidental nappe onto the continental sediments of the Interandean Valley, blanketing the Cordillera's eastern margin. As rotation and continental sedimentation onset ages are similar, we interpret such tectonic depression as a narrow flexural basin formed ahead of the advancing nappe front. The 20°–30° CW Neogene rotation of the Cordillera Occidental is indistinguishable from the post‐Cretaceous rotation of the Coastal forearc oceanic blocks, implying that the whole W Ecuador Andean chain was detached and rotated over a mid‐crustal detachment during the last 10 Ma. Eocene‐Miocene paleomagnetic inclination values are systematically consistent with those expected for South America, thus excluding latitudinal terrane drift. We suggest that the Andes of Ecuador and Peru form the “Ecuadorian Orocline”, formed by opposing orogenic rotations around the Amazonian craton indenter.
Thermal Structure of Eastern Australia's Upper Mantle and Its Relationship to Cenozoic Volcanic Activity and Dynamic Topography
Authors: Ball P. W. , Czarnota K. , White N. J. , Klöcking M. , Davies D. R. 
Published: July 2021

AbstractSpatio‐temporal changes of upper mantle structure play a significant role in generating and maintaining surface topography. Although geophysical models of upper mantle structure have become increasingly refined, there is a paucity of geologic constraints with respect to its present‐day state and temporal evolution. Cenozoic intraplate volcanic rocks that crop out across eastern Australia provide a significant opportunity to quantify mantle conditions at the time of emplacement and to independently validate geophysical estimates. This volcanic activity is divided into two categories: age‐progressive provinces that are generated by the sub‐plate passage of mantle plumes and age‐independent provinces that could be generated by convective upwelling at lithospheric steps. In this study, we acquired and analyzed 78 samples from both types of provinces across Queensland. These samples were incorporated into a comprehensive database of Australian Cenozoic volcanism assembled from legacy analyses. We use geochemical modeling techniques to estimate mantle temperature and lithospheric thickness beneath each province. Our results suggest that melting occurred at depths ≤80 km across eastern Australia. Prior to, or coincident with, onset of volcanism, lithospheric thinning as well as dynamic support from shallow convective processes could have triggered uplift of the Eastern Highlands. Mantle temperatures are inferred to be ∼50–100°C hotter beneath age‐progressive provinces that demarcate passage of the Cosgrove mantle plume than beneath age‐independent provinces. Even though this plume initiated as one of the hottest recorded during Cenozoic times, it appears to have thermally waned with time. These results are consistent with xenolith thermobarometric and geophysical studies.
Conjugate Fault Deformation Revealed by Aftershocks of the 2013 Mw6.6 Lushan Earthquake and Seismic Anisotropy Tomography
Authors: Liu Ying , Zhang Haijiang , Kendall John Michael , Wookey James 
Published: July 2021

AbstractSeismic anisotropy is sensitive to the alignment of minerals, fluid‐filled cracks, and fractures caused by fault deformation, thus providing a signature of fault deformation, especially in the aseismic layer. In this study, we use seismic traveltime anisotropy tomography to study the spatial distribution of azimuthal anisotropy in the region of the 2013 Mw 6.6 Lushan earthquake. Our analysis reveals both stress‐induced and structure‐controlled seismic anisotropy mechanisms. The distribution of seismicity and anisotropy clearly delineates conjugate faults in the seismogenic zone between depths of 8 and 15 km. Two near‐vertical stripes or zones of strong seismic anisotropy reveal the continuation of these faults into the diagenetic or overlying aseismic crust. The anisotropic corridors associated with the conjugate faults are interpreted in terms of the crystal preferred orientation of fault rock minerals, which may be enhanced by shear‐band compaction. Our results demonstrate how seismic anisotropy can provide new insights into fault deformation.