bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Ventilated and Unventilated Air Temperature Measurements in Inland Dronning Maud Land on the East Antarctic Plateau
Authors: Morino Shohei , Kurita Naoyuki , Hirasawa Naohiko , Motoyama Hideaki , Sugiura Konosuke , Lazzara Matthew , Mikolajczyk David , Welhouse Lee , Keller Linda , Weidner George 
Published: December 2021

Abstract
Surface temperature measurements with naturally ventilated (NV) sensors over the Antarctic Plateau are largely subject to systematic errors caused by solar radiative heating. Here we examined the radiative heating error in Dronning Maud Land on the East Antarctic Plateau using both the newly installed automatic weather stations (AWSs) at NDF and Relay Station and the existing AWSs at Relay Station and Dome Fuji. Two types of NV shields were used in these AWSs: a multiplate radiation shield and a simple cylinder-shaped shield. In austral summer, the temperature bias between the force-ventilated (FV) sensor and the NV sensor never reached zero because of continuous sunlight. The hourly mean temperature errors reached up to 8°C at noon on a sunny day with weak wind conditions. The errors increased linearly with increasing reflected shortwave radiation and decreased nonlinearly with increasing wind speed. These features were observed in both the multiplate and the cylinder-shaped shields. The magnitude of the errors of the multiplate shield was much larger than that of the cylinder-shaped shield. To quantify the radiative errors, we applied an existing correction model based on the regression approach and successfully reduced the errors by more than 70% after the correction. This indicates that we can use the corrected temperature data instead of quality controlled data, which removed warm bias during weak winds in inland Dronning Maud Land.
Using Social Media as a Survey Recruitment Strategy for Post-Secondary Students During the COVID-19 Pandemic
Authors: Purewal Simran , Ardiles Paola , Di Ruggiero Erica , Flores John Vincent L. , Mahmood Sana , Elhagehassan Hussein 
Published: December 2021

The COVID-19 pandemic rapidly forced Canadian post-secondary students into remote learning methods, with potential implications on their academic success and health. In recent years, the use of social media to promote research participation and as a strategy for communicating health messages has become increasingly popular. To better understand how the pandemic has impacted this population, we used social media platforms to recruit students to participate in a national bilingual COVID-19 Health Literacy Survey. The purpose of the survey was to assess the health literacy levels and online information-seeking behaviors of post-secondary students in relation to the coronavirus. This paper outlines the social media recruitment strategies used for promoting participation in the survey among Canadian post-secondary students during the pandemic. Facebook, Twitter, and Instagram accounts were created to promote the online survey. The objective of this paper is to examine the use of Instagram, Facebook, and Twitter as survey recruitment strategies tailored to students. Data analytics from these platforms were analyzed using descriptive statistics. We found that the most commonly used platform for survey dissemination was Twitter, with 64800 total impressions recorded over 3 months. The use of social media as a survey recruitment strategy showed promise in the current context of COVID-19 where many students are participating in online learning and for a study population that actively uses these platforms to seek out information.
Effects of different sedatives/analgesics on stress responses in patients undergoing craniotomy and bone flap decompression
Authors: Guo Qingduo , Ma Meina , Yang Qiuying , Yu Hong , Wang Xupeng , Wu Chunling , Li Rui 
Published: December 2021

Objective To explore the effects of sedation and analgesia with dexmedetomidine and other drugs on the stress response in patients with cerebral hemorrhage after craniotomy hematoma removal and bone flap decompression and insertion of an indwelling endotracheal catheter. Methods A total of 180 patients with cerebral hemorrhage with consciousness disturbance who underwent emergency surgery were included in this study. They were divided into six groups treated with propofol, dexmedetomidine, lidocaine, sufentanil, dezocine, and remifentanil, respectively. Intravenous medication was given after recovery of spontaneous respiration, and stress responses were compared among the group. Results Serum concentrations of norepinephrine, epinephrine, and cortisol and systolic blood pressure were significantly correlated with drug treatment. Serum norepinephrine concentrations differed significantly among the groups, except between the sufentanil and propofol groups. There were significant differences in serum epinephrine concentrations among all groups, and significant differences in serum cortisol concentrations among all groups, except the propofol, dexmedetomidine, and lidocaine groups. Conclusion Dexmedetomidine can reduce the stress response in patients with intracerebral hemorrhage undergoing emergency craniotomy and bone flap decompression, and can reduce adverse events from an indwelling endotracheal catheter 3 hours post-operation.
Lessons Learned for Emergency Feeding During Modifications to 11 School Feeding Programs in Latin America and the Caribbean During the COVID-19 Pandemic
Authors: Colón-Ramos Uriyoán , Monge-Rojas Rafael , Weil Jael Goldsmith , Olivares G Florencia , Zavala Rebecca , Grilo Mariana Fagundes , Parra Diana C. , Duran Ana Clara 
Published: December 2021

Background: School feeding programs (SFPs) can play a crucial role in the emergency food and nutrition response, but there is a dearth of information on how SFPs operate during emergencies. Design and Methods: A rapid comparative assessment of 11 SFPs throughout Latin America and the Caribbean during the COVID-19 pandemic. Data from (1) systematic document search and (2) surveys with key informants (n = 23) about barriers/facilitators to modifications were systematically analyzed using a multiple case study approach. Results: During the pandemic, all SFPs continued (although continuation plans varied from a few days in Chile to > 1 month in Puerto Rico) via food kits, food vouchers, and/or grab n’ go meals. The SFP implementation was highly dependent on the programs’ autonomy and financial support, which impacted their logistics to acquire and distribute foods during the pandemic. The types of foods offered in some SFPs suggest that established nutritional guidelines were not always followed. Key informants expressed concerns about the deterioration of the nutritional quality of foods offered during the pandemic and lack of community engagement that impeded distribution to the neediest. Conclusions: Results underscore the urgency for clear implementation guidance on how to modify SFP during emergencies. Public health implications include (1) allocation of autonomous resources to an intersectoral working group to safeguard nutritional benefits during emergencies, (2) strengthening efforts of SFP community engagement before and during emergencies, and (3) establishing guidelines of the types of foods that can be distributed to meet the nutritional needs of beneficiaries during emergencies.
High- Versus Low-Dose Dexamethasone for the Treatment of COVID-19-Related Acute Respiratory Distress Syndrome: A Multicenter, Randomized Open-Label Clinical Trial
Authors: Maskin Luis Patricio , Bonelli Ignacio , Olarte Gabriel Leonardo , Palizas Fernando , Velo Agostina E , Lurbet María Fernanda , Lovazzano Pablo , Kotsias Sophia , Attie Shiry , Lopez Saubidet Ignacio , Baredes Natalio D , Setten Mariano , Rodriguez Pablo Oscar 
Published: December 2021

Objective To determine whether high-dose dexamethasone increases the number of ventilator-free days (VFD) among patients with acute respiratory distress syndrome (ARDS) caused by COVID-19. Design Multicenter, randomized, open-label, clinical trial. Participants Consecutive patients with confirmed COVID-19-related ARDS were enrolled from June 17, 2020, to March 27, 2021, in four intensive care units (ICUs) in Argentina Intervention 16 mg of dexamethasone intravenously daily for five days followed by 8 mg of dexamethasone daily for five days or 6 mg of dexamethasone intravenously daily for 10 days. Main Outcome and Measures The primary outcome was ventilator-free days during the first 28 days. The secondary outcomes were all-cause mortality at 28 and 90 days, infection rate, muscle weakness, and glycemic control in the first 28 days. Results Data from 98 patients who received at least one dose of dexamethasone were analyzed. The trial was prematurely terminated due to low enrollment rate. At 28 days after randomization, there was no difference between high- and low-dose dexamethasone groups in VFD (median, 0 [interquartile range [IQR] 0-14] vs. 0 [IQR 0-1] days; P = .231), or in the mean duration of mechanical ventilation (19 ± 18 vs. 25 ± 22 days; P = .078). The cumulative hazard of successful discontinuation from mechanical ventilation was increased by the high-dose treatment (adjusted sub-distribution hazard ratio: 1.84; 95% CI: 1.31 to 2.5; P < .001). None of the prespecified secondary and safety outcomes showed a significant difference between treatment arms. Conclusions Among patients with ARDS due to COVID-19, the use of higher doses of dexamethasone compared with the recommended low-dose treatment did not show an increase in VFD. However, the higher dose significantly improved the time required to liberate them from the ventilator
Assessing Social Network Influences on Adult Physical Activity Using Social Network Analysis: A Systematic Review
Authors: Prochnow Tyler , Patterson Megan S. 
Published: December 2021

Objective Social network analysis (SNA) can measure social connectedness and assess impact of interpersonal connections on health behaviors, including physical activity (PA). This paper aims to systematically review adult PA studies using SNA to understand important social network concepts relative to PA. Data Source A search was performed using PsycINFO, MEDLINE, PubMed, and Web of Science. Study Inclusion and Exclusion Criteria To be included in the search, articles needed to 1) include a measure of PA, 2) conduct an SNA in which specific relationships were measured, and 3) conduct an analysis between social network measures and PA. Data Extraction Key study elements including network design and results were extracted. Data Synthesis Data were synthesized to answer 2 questions: 1) how has adult PA been investigated using SNA approaches and 2) how is an adult’s social network associated with PA behaviors? Results A final sample of 28 articles remained from an initial 11 085 articles. Network size, homophily, network composition, and network exposure to PA were all associated with individual level PA across studies. Lastly, longitudinal and intervention studies showed a more complex picture of social influence and diffusion of PA behavior. Conclusions Adults’ PA behaviors are influenced by their networks. Capitalizing on this influence, researchers should engage not just individual behavior change but also the social influences present within the person’s life.
Towards Zero Suicide for older adults: implications of healthcare service use for implementation
Authors: McKay Roderick , Pond Dimity , Wand Anne 
Published: December 2021

Objective: Implementing the Towards Zero Suicide (TZS) approach to suicide prevention in older adults requires evidence-based adaptation. This paper aims to highlight important differences and opportunities in healthcare service use by older adults relevant to implementation. Conclusion: The TZS approach may prevent suicide in older adults, but only if implementation aligns with systemic differences in healthcare utilisation by older people. Of greatest importance in older adults are (1) most mental healthcare is delivered outside of specialist mental health services; (2) physical conditions and disability are major modifiable contributors to suicide that must be addressed within TZS; and (3) older people have very low use of Medicare-funded psychological services. Primary healthcare providers, who may be seeing older people at risk of suicide, are often neither equipped to provide expert assessment and care planning for often complex needs, nor may see this as their role. However, they are essential in providing pathways to care, which may prevent suicide. Leaders must recognise TZS for older people will usually involve multiple transitions. This requires engagement of key services with clear roles, targeted training, rapid access to specialist older persons mental health support and development of a new TZS element: the navigator.
The Impact of Anticoagulant Activity of Tissue Factor Pathway Inhibitor Measured by a Novel Functional Assay for Predicting Deep Venous Thrombosis in Trauma Patients: A Prospective Nested Case-Control Study
Authors: Cao Xiangyu , Su Yu , Zhang Wenjie , Zhao Huiru , Wen Meng , Lu Shan , Zhao Yujing , Chen Yuying , Liu Lei , Zang Xinwei , Wu Jun 
Published: December 2021

Objective Deep venous thrombosis (DVT) is a common complication in patients with traumatic injury. Tissue factor pathway inhibitor (TFPI) is a natural anticoagulant protein in the extrinsic coagulation pathway. However, the relationship between DVT after trauma and the anticoagulant activity of TFPI remains unclear. In this prospective study, we investigated the role of TFPI in trauma patients with DVT to evaluate whether the anticoagulant activity of TFPI measured by a new functional assay can be used to help predict the risk of DVT. Patients and methods: This prospective nested case-control study enrolled trauma patients and healthy volunteers. Forty-eight trauma patients diagnosed with DVT and forty-eight matched trauma patients without DVT were included in the study. 120 healthy volunteers were also included as controls. Blood samples and case information were collected at admission. Patients accepted angiography before surgery to diagnose DVT. The parameters examined included TFPI anticoagulant activity, free-TFPI antigen, blood cell counts, and routine clinical coagulation tests. Results: For the parameters of TFPI anticoagulant activity, three were markedly increased in the DVT group compared to the non-DVT group (TFPI initial anticoagulant time ratio, P  =  .022; TFPI whole anticoagulant time ratio, P  =  .048; and TFPI anticoagulant rate, P  =  .034). The free-TFPI antigen concentration also showed a significant increasing trend in trauma patients with DVT compared with trauma patients without DVT (P  =  .035). Multivariate logistic regression analysis identified four independent factors for the development of DVT (TFPI initial anticoagulant time ratio, free-TFPI antigen, prothrombin time, and red blood cell count). We calculated the TFPI correlation coefficient and found that the area under the receiver operating characteristic curve was .821. Conclusions: A novel functional assay was developed to measure the anticoagulant activity of TFPI. The anticoagulant activity of TFPI can be used as a potential biomarker for diagnosing DVT in trauma patients.
Thoracic Endovascular Aortic Repair for Iatrogenic Injury of the Thoracic Aorta
Authors: Tharp Peyton , King Ryan W. , Frankel Bruce M. , Wooster Mathew D. 
Published: December 2021

Purpose: Address iatrogenic injury to the descending thoracic aorta by breached spinal screws through a novel approach of concomitant spinal screw removal and thoracic endovascular repair (TEVAR) placement. Case Report: A 36-year-old female with idiopathic scoliosis underwent T4 to L3 bilateral pedicle instrumentation with spinal fusion and correction of scoliosis deformity. Ten months post-operative, she continued to complain of mid-thoracic pain; computed tomography (CT) angiography revealed protrusion of the left T5 and T6 transpedicular screws into her descending thoracic aorta by 3 and 5 mm, respectively. She was taken to the odds ratio (OR) in a combination case with vascular and neurosurgery. Positioned in the right lateral decubitus position, TEVAR was successfully deployed while neurosurgery concurrently removed the invading spinal screws via posterior spinal exposure. Neurosurgery then completely revised the spinal hardware during the same operation. The patient progressed well throughout the remainder of her hospital stay and was discharged on postoperative day 4. Two-year angiography demonstrated a well-placed TEVAR with no extravasation or aortic abnormality. Conclusions: In the setting of iatrogenic aortic injury due to pedicle screws, concomitant TEVAR and spinal screw removal is a safe and feasible treatment option that allows for spinal reconstruction to occur without multiple trips to the operating room.
Neurokinins and their receptors in the rat trigeminal system: Differential localization and release with implications for migraine pain
Authors: Edvinsson Jacob CA , Reducha Philip V , Sheykhzade Majid , Warfvinge Karin , Haanes Kristian A , Edvinsson Lars 
Published: December 2021

Substance P (SP) and calcitonin gene-related peptide (CGRP) have both been considered potential drug candidates in migraine therapy. In recent years, CGRP receptor inhibition has been established as an effective treatment, in particular as a prophylactic for chronic migraine. Curiously, inhibition of neurokinin receptor 1 (NK1R) failed to alleviate acute migraine attacks in clinical trials, and the neurokinins were consequently abandoned as potential antimigraine candidates. The reason behind this has remained enigmatic. Utilizing immunohistochemistry and semi-quantitative cell counts the expression of neurokinins and their associated receptors was examined in the rat trigeminal ganglion. Immunohistochemistry results revealed SP co-localization in CGRP positive neurons and C-fibres, where it mainly concentrated at boutons. Neurokinin A (NKA) was observed in a population of C-fibres and small neurons where it could co-localize with SP. In contrast, neurokinin B (NKB) did not co-localize with SP and was observed in large/medium sized neurons and Aδ-fibres. All neurokinin receptors (NK1-3R) were found to be expressed in a majority of trigeminal ganglion neurons and A-fibres. The functional release of SP and CGRP in the trigeminovascular system was stimulated with either 60 mM K+ or 100 nM capsaicin and measured with an enzyme-linked immunosorbent assay (ELISA). ELISA results established that SP can be released locally from trigeminovascular system. The released SP was comparatively minor compared to the CGRP release from stimulated dura mater, trigeminal ganglion neurons and fibres. We hypothesize that SP and CGRP signalling pathways may work in tandem to exacerbate painful stimuli in the TGV system.
Subsistence Hunting During the COVID-19 Pandemic: The Case of the White-Tailed Deer (Odocoileus virginianus) in Rural Communities of Calakmul, Campeche, Mexico
Authors: Briceño-Méndez Marcos , Contreras-Perera Yamili , Montiel Salvador 
Published: December 2021

Subsistence hunting for obtaining wild meat is a common practice in rural neotropical communities. Like other peasant practices disrupted by the COVID-19 pandemic, subsistence hunting could exacerbate pressure on wild mammals whose greater size contributes to feeding the hunter and his family. Thus, in the context of the pandemic, we assessed the subsistence hunting of the white-tailed deer ( Odocoileus virginianus), one of the main traditional game species in the Calakmul region, Campeche, Mexico, and compared this activity with its pre-pandemic levels of such vertebrate species. Based on ethnographic information and hunting records from three rural communities, we found that in one trimester (July-September 2020) of the rainy season, a total of 26 white-tailed deer (923 kg of game biomass) were obtained by local peasant-hunters carrying out hunting mostly alone. Most peasant-hunters interviewed (36 of 51) stated that they hunted daily, and only a few hunted once a week or once a month (8 and 3%, respectively). This hunting activity and modalities were carried out at night (68%) versus day, stalking (21%) and opportunist (11%) near their community. The game biomass and hunting frequency in the studied communities were twice as high during the pandemic, compared to similar pre-pandemic periods in the region. Our survey highlights the need to expand monitoring and evaluation (during and after the pandemic) of subsistence hunting on key species, such as white-tailed deer, in order to ensure conservation and sustainable use of wildlife in this important Mesoamerican region.
The Relationship Between Arthroplasty Surgeons’ Experience Level and Optimal Cable Tensioning in the Fixation of Extended Trochanteric Osteotomy
Authors: Başarır Kerem , Kalem Mahmut , Şahin Ercan , Özbek Emre Anıl , Karaca Mustafa Onur , Küçükkarapınar İbrahim , Tönük Ergin 
Published: December 2021

Introduction In this study, our aim was to examine the relationship between the arthroplasty surgeons’ experience level and their aptitude to adjust the cable tension to the value recommended by the manufacturer when asked to provide fixation with cables in artificial bones that underwent extended trochanteric osteotomy (ETO). Materials and Methods A custom-made cable tensioning device with a microvoltmeter was used to measure the tension values in Newtons (N). An ETO was performed on 4 artificial femur bones. Surgeons at various levels of experience attending the IXth National Arthroplasty Congress were asked to fix the osteotomized fragment using 1.7-mm cables and the tensioning device. The participants’ demographic and experience data were investigated and recorded. The surgeons with different level of experience repeated the tensioning test 3 times and the average of these measurements were recorded. Results In 19 (35.2%) of the 54 participants, the force applied to the cable was found to be greater than the 490.33 N (50 kg) value recommended by the manufacturer. No statistically significant difference was determined between the surgeon’s years of experience, the number of cases, and the number of cables used and the tension applied over the recommended maximum value ( P = .475, P = .312, and P = .691, respectively). Conclusions No significant relationship was found between the arthroplasty surgeon’s level of experience and the adjustment of the cable with the correct tension level. For this reason, we believe that the use of tensioning devices with calibrated tension gauges by orthopedic surgeons would help in reducing the number of complications that may occur due to the cable.