bluuebunny/crossref_metadata_2025_split huggingface dataset:
The cost-effectiveness of sequential versus standard triple therapy for Helicobacter pylori eradication in Saudi Arabia
Authors: AlRuthia Yazed , Almadi Majid A. , Alqahtani Sadeem , Alrasheed Hala , Al-Owairdhi Mohammad , Alsohaibani Fahad 
Published: July 2021

Background:
The utilization rate of different treatment regimens for Helicobacter pylori infection is believed to be high; however, the cost-effectiveness of these regimens has not been examined before. Therefore, the aim of this study was to examine the cost-effectiveness of the two commonly prescribed treatments for H. pylori infection.

Methods:
The data of an open-label, single-center, randomized trial that compared the efficacy of sequential therapy (SQT) (i.e., esomeprazole 20 mg twice daily for 10 days, amoxicillin 1000 mg twice daily for 5 days, then clarithromycin 500 mg and tinidazole 500 mg twice daily for 5 days) to standard triple therapy (STT) (i.e., esomeprazole 20 mg, amoxicillin 1000 mg, and clarithromycin 500 twice daily for 14 days) in the eradication of H. pylori, as confirmed by the negative urea breath test (UBT), were used. Propensity score matching bin bootstrapping, with 10,000 replications and bias correction was conducted to generate the 95% confidence limits. Moreover, probabilistic sensitivity analysis was conducted by varying both the eradication rates and the costs of treatment regimens.

Results:
There were 82 and 88 patients who were on SQT and STT, respectively. Patients' mean age was 47 years, and approximately 55% of them were females. The mean treatment costs were SAR 2,075.51 (USD 553.47) and SAR 2,629.26 (USD 701.14) for SQT and STT, respectively. The mean eradication rates for SQT and STT were 63.41% and 67.05%, respectively. The mean difference in costs and eradication rates for SQT versus STT were SAR − 550.75 (95% CI: −563.84- −537.69) and − 3.64% (95% CI: −6.98- 5.88). The use of SQT was more likely to be cost saving and more effective with 56.25% confidence level, in comparison to STT.

Conclusion:
The use of SQT in the treatment of H. pylori seems to be more cost-effective than STT.
Exploring the Complex Pathways between the Fear of COVID-19 and Preventive Health Behavior among Nigerians: Mediation and Moderation Analyses
Authors: Ayandele Olusola , Ramos-Vera Cristian A. , Iorfa Steven K. , Chovwen Catherine O. , Olapegba Peter O. 
Published: July 2021

ABSTRACT.
Since COVID-19 currently has no proven cure but high morbidity and mortality, many people are living in fear of the virus along with other mental health challenges induced by the lockdowns and social distancing. Hence, this study aims to provide evidence on the co-occurrence and inter-relations between the fear of COVID-19, post-traumatic stress symptoms, and psychological distress in adherence to preventive health behavior among Nigerians. It also seeks to determine whether this process differs for men and women. The sample comprised 1,172 consenting young adults (mean age = 22.9 ± 6.6 years, 54.5% females) selected using a snowball sampling technique. Structural equation modeling (SEM) was used to test the mediation model of post-traumatic stress symptoms and psychological distress as parallel and serial mediators of the relationship between the fear of COVID-19 and preventive health behavior. The indirect effect of the fear of COVID-19 on preventive health behavior across gender was tested using moderation analysis. Results showed that post-traumatic stress symptoms and psychological distress serially and fully, in causal order, mediated the association between the fear of COVID-19 and preventive health behavior, and gender moderated the mediation effects. The research provides evidence that the fear of COVID-19 could trigger preventive health behavior through post-traumatic stress symptoms but reduces it through psychological distress, whereas the fear of COVID-19 has a slightly more positive impact on preventive health behavior among men.
Public Willingness and Hesitancy to Take the COVID-19 Vaccine in Afghanistan
Authors: Nemat Arash , Bahez Ayesha , Salih Mohibullah , Raufi Nahid , Noor Noor Ahmad Shah , Essar Mohammad Yasir , Ehsan Ehsanullah , Asady Abdullah 
Published: July 2021

ABSTRACT.
COVID-19 has been causing a global threat to almost all countries for more than one year. Vaccination of the majority of any country’s population is considered to be an effective way of controlling the spread and mortality of this infection. Therefore, it is important to assess the public’s willingness to be vaccinated against COVID-19. In this study, we evaluated the public willingness and hesitancy to take the vaccine in Afghanistan, during December 2020 and January 2021. Sociodemographic data, awareness on vaccine production, vaccine availability, willingness and hesitancy to take the COVID-19 vaccine were collected. The Statistical Package for Social Studies (SPSS) version 25 was used for data analysis. A total of 806 complete responses were received. Majority of the respondents were ≤ 40 years old (89.8%) and male (72.7%). Less than two-thirds (509; 63%) of the participants reported willingness to take the vaccine when it becomes available, whereas almost one-third (297; 37%) of them were hesitant to take the COVID-19 vaccine. More female than male respondents were willing to take the vaccine (χ2 = 13.176, P value = 0.001). A significant portion of the public were not willing to take the COVID-19 vaccine. In a country like Afghanistan, which already has a low coverage of vaccination, this could pose a challenge for the vaccination program against COVID-19 to be effective. The Ministry of Public Health should work on public trust and change people’s mindset about vaccine reality and efficacy to prevent the rejection of this health intervention.
HUBUNGAN KETERAMPILAN PENGELOLAAN KELAS OLEH GURU DENGAN PRESTASI BELAJAR PAK SISWA
Authors: P Julita Herawati 
Published: July 2021

Tujuan penelitian ini adalah untuk mengetahui hubungan keterampilan pengelolaan kelas oleh guru dengan prestasi belajar PAK. Populasi penelitian 135 orang. Sampel ditentukan secara acak (random sampling) sebesar 25% dari jumlah populasi yaitu 25 % x 135 orang = 33 orang. Instrument penelitian berupa angket dan test. Dari uji hipotesa diperoleh thitung ttabel(/2,n-2) yaitu 4,390 2,042. Maka diketahui terdapat hubungan yang positif dan signifikan antara keterampilan pengelolaan kelas oleh guru PAK dengan prestasi belajar PAK siswa kelas VIII SMP Negeri 2 Muara. Kata Kunci : guru, motivasi belajar
BERITAKAN INJIL KEPADA SEGALA MAKHLUK (Sebuah Uraian Ekologi-Teologis)
Authors: Gea Ibelala 
Published: July 2021

Artikel ini bertujuan mendeskripsikan hasil penelitian tentang bagaimana memberitakan Injil kepada seluruh makhluk, bertolak dari Markus 16:15-16. Dunia adalah sebagai alamat pemberitaan Injil, bukan hanya kepada manusia melainkan kepada segala makhluk. Penulis Injil Markus hendak menjelaskan bahwa dunia identik dengan kejahatan, sebab itu Injil berfungsi menggarami dunia yang penuh kejahatan itu, karena itu ketika Iniil diberitakan kepada orang-orang jahat, diharapkan akan mengubah mindset dan perilaku manusia. Perilaku manusia yang serakah dan tamak yang hanya memandang alam sebagai komoditi. Pemberitaan Injil adalah menyadarkan manusia agar tidak hanya memandang alam sebagai kekuasaan (dominio) tetapi sebagai sesama ciptaan, sahabat yang bersifat communio.Kata Kunci: Injil dan Segala makhluk
DAMPAK VARIASI GAYA MENGAJAR GURU PAK TERHADAP MOTIVASI BELAJAR SISWA KELAS VII SMP NEGERI 2 SIPAHUTAR KECAMATAN SIPAHUTAR KABUPATEN TAPANULI UTARA TAHUN PEMBELAJARAN 2018/2019
Authors: Napitupulu Tianggur Medi 
Published: July 2021

Penelitian ini bertujuan untuk mengetahui seberapa besar Dampak Variasi Gaya Mengajar Guru PAK Terhadap Motivasi Belajar siswa kelas VII SMP Negeri 2 Sipahutar Kecamatan Sipahutar Kabupaten Tapanuli Utara Tahun Pembelajaran 2018/2019. Dengan hipotesa penelitian terdapat Dampak yang positif dan signifikan Variasi Gaya Mengajar Guru PAK Terhadap Motivasi Belajar siswa kelas VII SMP Negeri 2 Sipahutar Kecamatan Sipahutar Kabupaten Tapanuli Utara Tahun Pembelajaran 2018/2019. Populasi penelitian ini adalah 159 siswa dan sampel 40 siswa. Instrument penelitian berupa angket tertutup Uji coba angket dilakukan kepada 30 siswa kelas VII SMP Negeri 2 Sipahutar diluar sampel penelitian. Uji validitas instrument menggunakan rumus koefisien korelasi Product Moment person diperoleh rhitungrtabel antara nilai 0,387- 0,7040,361 sehingg instrumen valid. Dan uji reliabilitas instrument dengan rumus formula Alpha diperoleh r11=0,826 untuk variabel X dan r11=0,826 untuk variabel X dan r11=0,895 untuk variabel Y dan ini berada pada interpretasi sangat kuat, sehingga instrument reliabel, dengan demikian angket dapat digunakan sebagai instrumen penelitian. Maka dapat disimpulkan bahwa Dampak variabel X (Variasi Gaya Mengajar Guru PAK) terhadap variabel Y (motivasi belajar siswa), Uji signifikan pengaruh dengan rumus: F=S2 /S2 diperoleh f f sebesar 31,461,80 maka hipotesa diterima yaitu terdapat motivasi belajar siswa kelas VII SMP Negeri 2 Sipahutar Kecamatan Sipahutar Kabupaten Tapanuli Utara Pembelajaran 2018/2019.Kata Kunci: Variasi Gaya Mengajar, Motivasi Belajar Siswa
TUGAS DAN TANGGUNGJAWAB GURU SEKOLAH MINGGU TERHADAP MASA DEPAN GEREJA
Authors: Simatupang Hasudungan 
Published: July 2021

The purpose of this study was to determine the role of Sunday school teachers in organizing a series of learning processes not just the responsibility of filling free time on Sundays. This type of research is qualitative, using devotional theological research methods trying to apply the meaning of discourse to the reader's personal life without being separated from the learning objectives. The results of this qualitative research show the role of Sunday school teachers in preparing the ecclesiastical generation through the learning process as an effort to foster a generation of Christian churches from an early age. The tendency to use the learning method used, namely participatory fun, is very suitable for children, it can be followed through prayer, spiritual chanting, alphabeticism, followed by psychomotor (physical) movements in interpreting the discourse of a number of previously set learning objectives. The children were very loved by God, and the children showed enthusiasm to praise God, they were very excited in a cheerful atmosphere following the fun learning process. Thus it can be concluded how important the role of Sunday school teachers is to prepare the Christian church generation from an early age according to God's will.BAHASA INDONESIA ABSTRACT: Tujuan penelitian ini untuk mengetahui peran guru Sekolah Minggu menyelenggarakan serangkaian proses pembelajaran tidak sekedar tanggung jawab mengisi waktu senggang pada hari minggu Jenis penelitian ini kualitatif, menggunakan metode penelitian teologis devosional berusaha menerapkan makna wacana pada kehidupan pribadi pembaca tanpa dapat dipisahkan dari tujuan pembelajaran. Hasil penelitian kualitatif ini memperlihatkan peran guru Sekolah Minggu mempersiapkan generasi gerejawi melalui proses pembelajaran sebagai upaya pembinaan generasi gereja Kristen sejak dini. Kecenderungan pemanfaatan metode pembelajaran yang digunakan yakni partisipatif menyenangkan sangat cocok bagi anak-anak, dapat diikuti melalui doa, nyanian rohani, mengabjad, diikuti gerakan-gerakan psikomotorik (fisik) dalam memaknai wacana sejumlah tujuan pembelajaran yang ditetapkan sebelumnya. Anak-anak sangat disayangi Tuhan, dan anak-anak menunjukkan antusiasme memuji Tuhan sangat bergelora dalam suasana riang gempita mengkuti proses pembelajaran menyenangkan. Dengan demikian disimpulkan betapa pentingnya peran guru sekolah minggu mempersiapkan generasi gereja Kristen sejak dini sesuai kehendak Tuhan.
PERENCANAAN GEDUNG BERLANTAI BANYAK DENGAN METODE SISTEM RANGKA PEMIKUL MOMEN KHUSUS (SRPMK) KABUPATEN TANA TORAJA
Authors: Matana Hernita , Rangan Parea Rusan , AmpangAllo Bastian A 
Published: July 2021

Perencanaan struktur bangunan tahan gempa sangat penting di Indonesia. Kabupaten Tana Toraja termasuk KDS-D dengan kategori resiko I dalam kelas situs SD. Sehingga metode Sistem Rangka Pemikul Momen Khusus (SRPMK) dapat digunakan dalam perencanaan. Perencanaan struktur gedung ini menggunakan konsep desain kapasitas berupa kolom kuat balok lemah. saat terjadi gempa yang kuat dengan metode tersebut diharapkan gedung ini tidak mengalami keruntuhan total.
Dalam perencanaan ini, bangunan yang direncanakan adalah bangunan fiktif 15 lantai menggunakan beton bertulang dengan panjang bangunan 40 m, lebar bangunan 14 m, tinggi 55.8 m dengan fungsi sebagai hotel. Perencanaan dan perhitungan struktur gedung ini ditinjau terhadap beban mati, beban hidup, dan beban gempa. Perhitungan beban mati dan beban hidup mengikuti persyaratan SNI 1727-2013, dan beban gempa dianalisis secara statik dan dinamis mengikuti persyaratan SNI 1726-2012. Untuk analisa struktur bangunan digunakan aplikasi SAP2000V21. Hasil analisis dan desain menunjukkan dimensi balok dan kolom telah memenuhi kriteria penampang untuk SRPMK, dimana syarat “strong column weak beam” telah terpenuhi.

Kata kunci : SRPMK, Gempa, Beton bertulang, Kolom kuat balok lemah
REPRESENTASI STAILISTIK FILEM HANG TUAH (1956)
Authors: HAMADUN FAIRULADILAN , ABDILLAH NASIRIN , YUSOFF NORMAN , NOR ADZLI NUR SYAHIRAH ANANI 
Published: July 2021

Abstrak
Hang Tuah (1956) merupakan salah satu filem adaptasi Melayu yang terkenal dalam sejarah perfileman tanah air. Filem ini dikatakan cuba mengangkat karya kesusasteraan Melayu klasik melalui Hikayat Hang Tuah dan Sejarah Melayu. Memandangkan filem ini bersifat adaptasi, maka sering menjadi perhatian dalam kalangan sarjana. Antara aspek yang sering menjadi daya tarikan mereka adalah soal kesetiaan dalam aspek naratif seperti plot, lakonan, gaya bahasa, latar dan tema. Namun demikian, artikel ini hadir dengan melihat kepada aspek lain iaitu stailistik yang mana merupakan salah satu elemen penting dalam pembuatan filem seperti sinematografi, mise en scene dan penyuntingan. Aspek stailistik filem Hang Tuah (1956) cuba diselami dengan mengaplikasikan teori historical poetic of cinema oleh David Bordwell (1989). Sebagai kerangka analisis utama dalam artikel ini, maka historical poetic of cinema cuba menjawab persoalan kajian; bagaimanakah aspek sejarah mampu memberi kesan terhadap stailistik filem Hang Tuah (1956)? Analisis kandungan turut dipilih sebagai instrumen kajian utama untuk memperolehi data daripada buku, artikel jurnal dan filem. Hasil analisis mendapati bahawa filem Hang Tuah (1956) cenderung kepada stailistik model pembuatan Hollywood. Walau bagaimanapun, keadaan persekitaran industri perfileman Melayu era 1950-an cuba mengubah stailistik filem Hang Tuah (1956) kepada acuan filem India.

AbstractHang Tuah (1956) is one of the famous adaptation films in Malay cinema. The film endeavours to uplift the classical Malay literature through the Hikayat Hang Tuah and Sejarah Melayu. Since Hang Tuah (1956) is an adaptation film, it has always attracted the scholars’ attention. Among the main attractions is the matter of loyalty in the narrative aspects such as plot, acting, language style, background and theme. However, this article looks at other aspect namely stylistics. This important element of stylistics in film production includes cinematography, mise en scene and editing. The stylistics aspect of Hang Tuah (1956) was investigated by applying the historical poetic theory of cinema by David Bordwell (1989). As the main analytical framework in this article, historical poetic of cinema attempts to answer the research question of how the historical aspects can affect the style of Hang Tuah (1956) film? Content analysis was chosen as the main instrument for obtaining data from books, journal articles and films. The analysis found that Hang Tuah (1956) tends to resemble Hollywood production model. However, the environment of Malay film industry around 1950’s had influenced the stylistics of Hang Tuah (1956) film to be shaped by an Indian mould.
SIMBOL PADA REKABENTUK MASJID MUHAMMADI, KOTA BHARU, KELANTAN: SATU PENELITIAN AWAL
Authors: HANIM SAIDI NUR NAJWA , MOHAMED ROSDI NORAZLINDA , DAENG JAMAL DAENG HALIZA 
Published: July 2021

Abstrak
Simbol memainkan peranan penting dalam melihat keindahan nilai estetika sesuatu rekabentuk bangunan masjid. Ini kerana keunikan rekabentuk sesebuah masjid warisan banyak dipengaruhi oleh rekabentuk simbol yang dipilih yang mempunyai falsafah tertentu. Pemilihan simbol yang tepat menjadikan rekabentuk masjid lebih menarik dan cantik. Kajian ini bertujuan merungkai pemilihan simbol bagi setiap rekabentuk pada bangunan Masjid Muhammadi, Kota Bharu Kelantan. Simbol yang diambilkira dalam kajian ini adalah termasuk ragam hias, motif (flora dan fauna), geometri dan kaligrafi. Kaedah penyelidikan yang digunakan untuk mendapatkan maklumat ialah melalui kaedah pemerhatian. Kaedah pemerhatian ini digunakan bagi melihat ragam hias dalam rekabentuk Masjid Muhammadi. Hasil kajian menunjukkan simbol yang digunakan dalam ragam hias masjid warisan ini lebih menekankan kepada motif yang berunsurkan alam flora, kaligrafi dan corak.

Abstract
Symbol has an important role in appreciating the aesthetic value of a heritage mosque. The uniqueness of a heritage mosque is influenced by the selected symbols which have their own philosophy. A right selection can make the design of the mosque more attractive and more beautiful. This study aims to unravel the selection of symbols in the design of Masjid Muhammadi, Kota Bharu Kelantan. These symbols include decoration, motifs (flora and fauna), geometry and calligraphy. The research method used to obtain information is qualitative through observation. It is observed that the symbols used in the decoration of this heritage mosque are more of a motif based on the nature of flora, calligraphy and patterns.
Türkiye'de "Yerel Diplomasi Yönetimi"ne Dair Bir Araştırma
Authors: ERDEM Nisa , ERSAVAŞ KAVANOZ Suna 
Published: July 2021

Kentler, ulusal sınırların ötesindeki eylemleriyle küreselleşeme sürecinde birer aktör olarak öne çıkmaktadırlar. Bu durum, kentsel girişimciliğin yerel ötesi sınırlarda yeniden tanımlanmasıyla birer siyasal aktör olarak yerel yönetimlerin kurumsal kapasitesini etkilemekte, bir dereceye kadar “hareket etme” gücünü artırmaktadır.
Bu çalışmanın amacı, yerel diplomasi yönetiminin/kurumsallaşmasının belediye bünyesinde söz konusu yerel diplomasi faaliyetlerinin dış ilişkiler birimi ve personel yapıları bağlamında araştırılarak ortaya konulmasını içermektedir. Araştırma kapsamına Türkiye’de dış ilişkiler birimi bulunan belediyeler dâhil edilmiştir. Araştırma neticesinde elde edilen bulgular, belediyelerin ilgili kurumsal web sayfalarının taranması ve dış ilişkiler birimi bulunan belediyelerde ilgili birim personelleri ile yapılan görüşmeler neticesinde elde edilmiştir.
Kent yönetimlerinin uluslararası ilişkilerine dair politikalarını yönetecek ve yürütecek birimlerin kurulmasıyla yerel diplomatik faaliyetler, zaman içinde öğrenme sürecinden geçerek, yönetimsel bağlamda daha profesyonel bir yapıya kavuşmaktadır. Kent yönetimlerinin uluslararası ilişkilerine dair politikalarını yürütecek birimlerin, ofislerin kurulması başka bir ifadeyle yerel yönetimlerin uluslararası ilişkilerinin profesyonelleşmesi, “yerel diplomasinin yönetimi/kurumsallaşması” kavramıyla ifade edilebilir. Türkiye’de ‘yerel diplomasi yönetiminin/kurumsallaşmasının’ gelişimi yerel süreçlerin yansıması olduğu kadar ulusal politikaların da etki ettiği bir alandır. Belirli dönemlerdeki içsel ve dışsal değişimler yerel diplomasi yönetimine yön vermektedir.
Cytotoxicity and anti-small cell lung cancer potential of 3-methoxy-5-nitrosalicylaldehyde: an analog for treatment of diabetes mellitus with considerable binding affinity to α-amylase enzyme
Authors: Wen Hongqing , Wang Junyan , Alotaibi Saad H. 
Published: July 2021

Introductionα-Amylase inhibitors are present in plants and are thought to be produced by plants to strengthen their defenses against predators. They include plant components, polyphenolic compounds and glycoproteins with enzymatic inhibitory activity.Material and methodsIn this study, the inhibitory effect of metabolic enzyme was obtained, IC50: 95.14 µM. The molecular docking investigation was performed as a versatile method for the evaluation of the biological activities of 3-methoxy-5-nitrosalicylaldehyde in the presence of α-amylase. The compound exhibited a considerable binding affinity to the enzyme with a docking score of –7.676 kcal/mol.ResultsThe results of the molecular docking revealed that 3-methoxy-5-nitrosalicylaldehyde is able to construct hydrophobic contacts with crucial residues of the catalytic domain of the enzyme. According to these findings, the compound has the potential to be an inhibitor of α-amylase. The MTT test was used on normal (human umbilical vein endothelial cells (HUVECs)) and small cell lung cancer (SBC-3, DMS273, and DMS114) cell lines. 3-Methoxy-5-nitrosalicylaldehyde had high cell death and anti-small cell lung cancer effects against SBC-3, DMS273, and DMS114 cell lines. Among the above cell lines, the best result of anti-small cell lung cancer properties of the molecule was obtained in the cell line DMS273.ConclusionsThe results of this study indicated the excellent anti-small cell lung cancer potential of 3-methoxy-5-nitrosalicylaldehyde in in vitro conditions. After confirming the above results in the clinical trial research, this formulation may be administrated for the treatment of several types of small cell lung cancer in humans.
No licence for love versus same-sex relationships –
partner relations and interpersonal commitment
Authors: Janicka Iwona Lidia 
Published: July 2021

IntroductionLike heterosexual ones, homosexual partners strive to fulfil their needs for belonging and love. They also build their relationships in countries where less favourable public opinion exists towards same-sex relationships, due in part to the lack of equivalent legislation between heterosexual and non-heterosexual persons and couples. As opponents of such relationships claim them to be less stable and of lower quality, the current study examines whether the sexual orientation of partners may determine the quality of their relationship and their commitment to it.Material and methodsThe study was conducted in a group of 530 cohabiting persons, aged 18-44 (230 persons with a homosexual orientation and 300 heterosexual) living in Poland. The participants were tested with three tools: a sociodemographic survey, the Polish version of the Partner Relations Questionnaire by Halhweg, adapted by Janicka, and the Interpersonal Commitment Inventory (KZI) by Janicka and Szymczak: the Polish adaptation of the Commitment Inventory by Stanley and Markman.ResultsThe findings indicate that sexual orientation of women and men may influence their tendencies to change partners and their interpersonal commitment, interpreted as their dedication and obligation to stay in the relationship.ConclusionsSome detailed analyses suggest that cohabitations between gay women portend better than those of gay men.