bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of endocrine disorders among children exposed to Lavender Essential Oil and Tea Tree Essential Oils
Authors: Hawkins Jessie , Hires Christy , Dunne Elizabeth , Keenan Lindsey 
Published: October 2021

Background:
Lavender essential oil and tea tree essential oil have become popular ingredients in personal care and household products in recent decades. Questions regarding the safety of these oils in pediatric populations have been raised, proposing a link between these essential oils and endocrine disruption in children, specifically prepubertal gynecomastia. To date, no epidemiological studies have been conducted to evaluate this proposed link.

Methods:
This is a cross sectional study conducted among parents of children in the United States to identify the prevalence of endocrine disruption in children aged 2—15 years old. This study also evaluates the potential for a relationship between the exposure of lavender essential oil and tea tree essential oil products and endocrine disrupting outcomes.

Results:
In 556 children with a mean age of 6.33 (SD = 3.92), prevalence of endocrine disruption was .016 (SD = 0.13). No cases of prepubertal gynecomastia were identified in either group, and prevalence of precocious puberty, delayed puberty, growth hormone deficiency, and hypothyroidism were all consis-tent with population norms. Total risk of endocrine disorders among those exposed (0.0194) did not differ from the risk of those unexposed (0.0069). The risk ratio was 2.796 (95% CI: 0.352,22.163, P = .458).

Conclusion:
Children who were regularly exposed to lavender or tea tree essential oils experienced the same risk of endocrine disorders as those who were not exposed.
Closed Reduction of Anterior Shoulder Dislocations Performed by Ski Patrollers in the Alpine Prehospital Environment: A Retrospective Review Demonstrating Efficacy in a Canadian Ski Resort
Authors: Mulvey Jamin M. , Carson Ira N. , Palmer Kevin A. 
Published: October 2021

Introduction Shoulder dislocations are common ski hill injuries. Rapid reduction is known to improve outcomes; however, advanced providers are not always available to provide care to these patients. In 2017, nonmedical ski patrollers at Sunshine Village ski resort in Alberta, Canada, were trained to perform anterior shoulder dislocation (ASD) reductions. Program success was determined by a chart review after the 2020 ski season. Methods This study retrospectively reviewed data on patients who presented to Sunshine Village ski patrol with a suspected ASD and who met the study inclusion criteria from November 2017 through March 2020. Data were collected from ski patrol electronic patient care records regarding general demographics, reduction technique used, analgesia administration, and reduction success rates. Results Ninety-six cases were available for review after exclusions. Trained nonmedical ski patrollers successfully reduced 82 of these cases, resulting in an overall reduction success rate of 89%. Sixty-three (66%) of these patients had experienced first-time dislocations. Eighty-two (87%) patients were male, with a median age of 25 y. The most used technique was the Cunningham method (75%), and analgesia was administered to 70% of patients. Conclusions This retrospective study documents the results of a quality assurance review of the treatment of ASD at Sunshine Village ski resort. With a success rate of 89%, the evidence supports the conclusion that nonmedical ski patrollers can successfully perform ASD reductions. We believe training ski patrollers to reduce ASD improved patient care in our austere environment by providing early definitive treatment with a high success rate.
High-fidelity aerodynamic modeling of an aircraft using OpenFoam – application on the CRJ700
Authors: Segui M. , Abel F.R. , Botez R.M. , Ceruti A. 
Published: October 2021

AbstractThis study is focused on the development of longitudinal aerodynamic models for steady flight conditions. While several commercial solvers are available for this type of work, we seek to evaluate the accuracy of an open source software. This study aims to verify and demonstrate the accuracy of the OpenFoam solver when it is used on basic computers (32–64GB of RAM and eight cores). A new methodology was developed to show how an aerodynamic model of an aircraft could be designed using OpenFoam software. The mesh and the simulations were designed only using OpenFoam utilities, such as blockMesh, snappyHexMesh, simpleFoam and rhoSimpleFoam. For the methodology illustration, the process was applied to the Bombardier CRJ700 aircraft and simulations were performed for its flight envelope, up to M0.79. Forces and moments obtained with the OpenFoam model were compared with an accurate flight data source (level D flight simulator). Excellent results in data agreement were obtained with a maximum absolute error of 0.0026 for the drag coefficient, thus validating a high-fidelity aerodynamic model for the Bombardier CRJ-700 aircraft.
DISCRIMINATION-FREE INSURANCE PRICING
Authors: Lindholm M. , Richman R. , Tsanakas A. , Wüthrich M.V. 
Published: October 2021

AbstractWe consider the following question: given information on individual policyholder characteristics, how can we ensure that insurance prices do not discriminate with respect to protected characteristics, such as gender? We address the issues of direct and indirect discrimination, the latter resulting from implicit learning of protected characteristics from nonprotected ones. We provide rigorous mathematical definitions for direct and indirect discrimination, and we introduce a simple formula for discrimination-free pricing, that avoids both direct and indirect discrimination. Our formula works in any statistical model. We demonstrate its application on a health insurance example, using a state-of-the-art generalized linear model and a neural network regression model. An important conclusion is that discrimination-free pricing in general requires collection of policyholders’ discriminatory characteristics, posing potential challenges in relation to policyholder’s privacy concerns.
The effects of absent fathers on adolescent criminal activity: an economic approach
Authors: Zimmer David M. 
Published: October 2021

AbstractSimple ordinary least squares estimates indicate that absent fathers boost probabilities of adolescent criminal behavior by 16–38%, but those numbers likely are biased by unobserved heterogeneity. This paper first presents an economic model explaining that unobserved heterogeneity. Then turning to empirics, fixed effects, which attempt to address that bias, suggest that absent fathers reduce certain types of adolescent crime, while lagged-dependent variable models suggest the opposite. Those conflicting conclusions are resolved by an approach that combines those two estimators using an orthogonal reparameterization approach, with model parameters calculated using a Bayesian algorithm. The main finding is that absent fathers do not appear to directly affect adolescent criminal activity. Rather, families with absent fathers possess traits that appear to correlate with increased adolescent criminal behaviors.
The better angels of our digital nature? Offensive cyber capabilities and state violence
Authors: Egloff Florian J. , Shires James 
Published: October 2021

AbstractTransformations in state violence are intimately associated with technological capacity. Like previous era-defining technologies, global digital networks have changed state violence. Offensive cyber capabilities (OCCs) appear to constitute a major technological development that offers the potential for reducing state violence. This article asks: are OCCs really the better angels of our digital nature? Current scholarship in strategic studies, adopting a narrow definition of violence, conceives of OCCs as largely non-violent. This ignores how technology has given rise to new forms of harm to individuals and communities, particularly in the context of violent state repression. We propose using an expanded definition of violence, including affective and community harms, and argue that OCCs relocate, rather than reduce, state violence towards non-bodily harms. Even though their lethal effects are limited, OCCs are not, as is supposed, a non-violent addition to state arsenals. This conclusion has important implications for international affairs, including re-orienting defensive cybersecurity efforts and altering calculations around the perception of OCCs by adversaries.
Interaction effects of socio-economic position in the association between eating location and diet quality in Portuguese children and adolescents: results from the National Food, Nutrition and Physical Activity Survey 2015–2016
Authors: Pimenta Pedro , Lopes Carla Maria Moura , Correia Daniela Macedo , Torres Duarte Paulo Martins , Rodrigues Sara Simões Pereira , Vilela Sofia 
Published: October 2021

AbstractThis study aims to evaluate the interaction effect of socio-economic environment (SEE) in the relationship between the eating location (EL) and diet quality, in children and adolescents. Data included Portuguese children and adolescents (3–17 years) from a National Dietary Survey Sample (IAN-AF 2015/2016,n987). Dietary intake was obtained by 2-d food diaries (children) or 2–24-h-recall (adolescents). Participants were classified into four groups of EL: ‘Home’, ‘Other homes’, ‘School’ and ‘Restaurants’. Diet quality was measured as a higher adherence to a healthy eating pattern. A previous developed socio-economic classification was used, and participants were grouped as belonging to a low socio-economic environment (LSE) or middle-high socio-economic environment (MHSE). Linear regression models were used to evaluate the association between EL and diet quality, stratified by the SEE. A statistically significant interaction effect was found (P< 0·01) for the SEE in the association between EL and diet quality. After adjustment for potential confounders, in LSE, participants belonging to ‘Other homes’ (β= –2·07; 95 % CI:–3·70, –0·44) and ‘Restaurants’ (β= –3·31; 95 % CI: –5·08, –1·54) had lower scores in the diet quality score, comparing to ‘Home’. In MHSE, comparing with ‘Home’, ‘Restaurants’ showed lower diet quality (β= –1·56; 95 % CI:–2·65, –0·48), while the ‘School’ had better diet quality (β= 0·90; 95 % CI: 0·16, 1·64). The SEE influences the association between EL and diet quality and, belonging to more disadvantaged SEE, might represent a higher risk of unhealthy eating habits when eating out-of-home.
Betaine supplementation fails to improve body composition: a systematic review and meta-analysis
Authors: Ashtary-Larky Damoon , Bagheri Reza , Tinsley Grant M. , Asbaghi Omid , Salehpour Sara , Kashkooli Sara , Kooti Wesam , Wong Alexei 
Published: October 2021

AbstractPrevious studies evaluating the effects of betaine supplementation on body composition offer contradictory findings. This systematic review and meta-analysis assessed the effects of betaine supplementation on body composition indices (body mass (BM), BMI, body fat percentage (BFP), fat mass (FM), fat-free mass (FFM)), and dietary intakes. Studies examining the effects of betaine supplementation on body composition and dietary intakes published up to August 2021 were identified through PubMed, the Cochrane Library, Web of Science, Embase, SCOPUS and Ovid databases. Betaine supplementation failed to significantly affect BM ((weighted mean difference (WMD): −0·40 kg, 95 % CI −1·46, 0·64), P = 0·447), BMI ((WMD: −0·05 kg/m2, 95 % CI −0·36, 0·25), P = 0·719), BFP ((WMD: 0·26 %, 95 % CI −0·82, 1·36), P = 0·663), FM ((WMD: −0·57 kg, 95 % CI −2·14, 0·99), P = 0·473) and FFM ((WMD: 0·61 kg, 95 % CI −1·27, 2·49), P = 0·527). Subgroup analyses based on participant’s age (< 40 and > 40 years), sex, BMI, trial duration (< 8 and ≥ 8 weeks), betaine supplementation dosage (< 4 and ≥ 4 g) and health status (healthy or unhealthy) demonstrated similar results. Other than a potential negligible increase in protein intake (WMD: 3·56 g, 95 % CI 0·24, 6·88, P = 0·035), no changes in dietary intakes were observed following betaine supplementation compared with control. The present systematic review and meta-analysis does not show any beneficial effects of betaine supplementation on body composition indices (BM, BMI, FM and FFM).
Access to Pharmaceutical Patents in the COVID-19 Emergency: A Case for Government Use in Nigeria
Authors: Adewopo Adebambo 
Published: October 2021

AbstractThe COVID-19 pandemic has continued to exert enormous pressure on public health policies and systems, with far-reaching implications. The race for vaccines has raised important intellectual property rights issues. These are evident in the need to advance the public interest and in the obligation of governments to address the challenge of access to vaccines, especially in sub-Saharan countries like Nigeria with relatively underdeveloped healthcare and innovation ecosystems. While the Nigerian Patents and Designs Act (PDA) establishes a compulsory licence regime that affords access to patented drugs, existing public healthcare is severely challenged in providing access tonewmedicines. This article examines the framework for patent protection of pharmaceuticals designed to meet public health challenges, such as those presented by the pandemic. It recommends the implementation of a government use provision under the PDA, with a view to addressing the challenge of access to COVID-19 vaccines.
Machine learning in the prediction of depression treatment outcomes: a systematic review and meta-analysis
Authors: Sajjadian Mehri , Lam Raymond W. , Milev Roumen , Rotzinger Susan , Frey Benicio N. , Soares Claudio N. , Parikh Sagar V. , Foster Jane A. , Turecki Gustavo , Müller Daniel J. , Strother Stephen C. , Farzan Faranak , Kennedy Sidney H. , Uher Rudolf 
Published: October 2021

AbstractBackgroundMultiple treatments are effective for major depressive disorder (MDD), but the outcomes of each treatment vary broadly among individuals. Accurate prediction of outcomes is needed to help select a treatment that is likely to work for a given person. We aim to examine the performance of machine learning methods in delivering replicable predictions of treatment outcomes.MethodsOf 7732 non-duplicate records identified through literature search, we retained 59 eligible reports and extracted data on sample, treatment, predictors, machine learning method, and treatment outcome prediction. A minimum sample size of 100 and an adequate validation method were used to identify adequate-quality studies. The effects of study features on prediction accuracy were tested with mixed-effects models. Fifty-four of the studies provided accuracy estimates or other estimates that allowed calculation of balanced accuracy of predicting outcomes of treatment.ResultsEight adequate-quality studies reported a mean accuracy of 0.63 [95% confidence interval (CI) 0.56–0.71], which was significantly lower than a mean accuracy of 0.75 (95% CI 0.72–0.78) in the other 46 studies. Among the adequate-quality studies, accuracies were higher when predicting treatment resistance (0.69) and lower when predicting remission (0.60) or response (0.56). The choice of machine learning method, feature selection, and the ratio of features to individuals were not associated with reported accuracy.ConclusionsThe negative relationship between study quality and prediction accuracy, combined with a lack of independent replication, invites caution when evaluating the potential of machine learning applications for personalizing the treatment of depression.
Headache in ADHD as comorbidity and a side effect of medications: a systematic review and meta-analysis
Authors: Pan Pei-Yin , Jonsson Ulf , Şahpazoğlu Çakmak Sabriye Selin , Häge Alexander , Hohmann Sarah , Nobel Norrman Hjalmar , Buitelaar Jan K. , Banaschewski Tobias , Cortese Samuele , Coghill David , Bölte Sven 
Published: October 2021

AbstractThere is mixed evidence on the association between headache and attention-deficit/hyperactivity disorder (ADHD), as well as headache and ADHD medications. This systematic review and meta-analysis investigated the co-occurrence of headache in children with ADHD, and the effects of ADHD medications on headache. Embase, Medline and PsycInfo were searched for population-based and clinical studies comparing the prevalence of headache in ADHD and controls through January 26, 2021. In addition, we updated the search of a previous systematic review and network meta-analysis of double-blind randomized controlled trials (RCTs) on ADHD medications on June 16, 2020. Trials of amphetamines, atomoxetine, bupropion, clonidine, guanfacine, methylphenidate, and modafinil with a placebo arm and reporting data on headache as an adverse event, were included. Thirteen epidemiological studies and 58 clinical trials were eligible for inclusion. In epidemiological studies, a significant association between headache and ADHD was found [odds ratio (OR) = 2.01, 95% confidence interval (CI) = 1.63–2.46], which remained significant when limited to studies reporting ORs adjusted for possible confounders. The pooled prevalence of headaches in children with ADHD was 26.6%. In RCTs, three ADHD medications were associated with increased headache during treatment periods, compared to placebo: atomoxetine (OR = 1.29, 95% CI = 1.06–1.56), guanfacine (OR = 1.43, 95% CI = 1.12–1.82), and methylphenidate (OR = 1.33, 95% CI = 1.09–1.63). The summarized evidence suggests that headache is common in children with ADHD, both as part of the clinical presentation as such and as a side effect of some standard medications. Monitoring and clinical management strategies of headache in ADHD, in general, and during pharmacological treatment are recommended.
On the Informal Rules of the Chinese Communist Party
Authors: Smith Ewan 
Published: October 2021

AbstractThe Chinese Communist Party (CCP) is a closely constituted party. Recent studies of the CCP describe and evaluate its formal rules, but to understand the Party as an institution we also need to understand its informal rules. The literature on “party norms”, “institutionalization” and the “unwritten constitution” often fails to distinguish rules from other political phenomena. It confuses informal rules with political practices, constitutional conventions, behavioural equilibria and doctrinal discourse. It is prone to overlook important rules, and to see rules where there are none. Hence, it potentially overstates how institutionalized the CCP is, and therefore how resilient it is. The article provides a clearer account of informal rules and suggests a different explanation for the resilience of the CCP.
Chinese politics and comparative authoritarianism: institutionalization and adaptation for regime resilience
Authors: Takeuchi Hiroki , Desai Saavni 
Published: October 2021

AbstractChina's authoritarian regime under the Chinese Communist Party (CCP) remains resilient and responsive to domestic and international threats to its survival, especially considering the inherent instability of other authoritarian regimes. What strategies allow the CCP to stay in power? How do institutions help the CCP to sustain one-party rule, if at all? How does the regime maintain centralized rule over its vast population and territory? Finally, how does the regime respond to the people's demands and dissatisfactions? This review essay discusses how the growing literature of comparative authoritarianism helps (or does not help) us to answer these questions. It discusses three books – one on comparative authoritarianism and two on Chinese politics. InHow Dictatorships Work: Power, Personalization, and Collapse, the authors (i.e., Barbara Geddes, Joseph Wright, and Erica Frantz) test various hypotheses exploring the issues regarding the central political processes that shape the policy choices of authoritarian regimes, such as seizing power, consolidation of elites, information gathering, and how dictatorships break down. Are their findings consistent or contradictory with observation of Chinese authoritarian politics? To answer this question, we draw empirical evidence from Bruce Dickson'sThe Dictator's Dilemma: The Chinese Communist Party's Strategy for Survivaland Min Ye'sThe Belt Road and Beyond: State Mobilized Globalization in China, 1998–2018. These books suggest why China's authoritarian regime remains resilient.
Dual-band-notched UWB MIMO antennas with miniaturization using half-cutting technology
Authors: Du Zhonghong , Zhang Xiaohui , Qin Peiyu , Yuan Yanning , Liu Jiangfan , Xi Xiaoli 
Published: October 2021

Abstract
A compact four-element ultra-wideband (UWB) multiple-input–multiple-output (MIMO) antenna with dual polarization and dual-notched capabilities was developed and fabricated. The MIMO antenna is composed of four orthogonally placed half-cutting UWB antenna elements. This orthogonal placement improves the isolation. Furthermore, an L-shaped slot and a continuous bending slot are etched to realize the band-rejection function in the WiMAX and WLAN bands. The result shows that the antenna achieved operating bands of 2.9–16.5 GHz (140.2%, S11 < −10 dB), fully covering the UWB (3.1–10.6 GHz). The port isolation is greater than 23 dB in the frequency band of interest, excluding two rejected bands. Moreover, the MIMO antenna has excellent diversity performance, such as a low envelope correlation coefficient (<0.004), high diversity gain (approximately 10 dB), and good omnidirectional radiation characteristics.
Detention in the context of counterterrorism and armed conflict: Continuities and new challenges
Authors: Hill-Cawthorne Lawrence 
Published: October 2021

AbstractThis article explores recent practices of States in relation to counterterrorism and armed conflict detention. Recent cases in the courts of the UK and US are drawn on to demonstrate the continued defence by those States of their administrative detention practices. Furthermore, the practice of other States in adopting new administrative detention laws as part of their counterterrorism strategies is explored. Finally, two examples of contemporary controversies are then considered to show where much of the debate is likely to be focused in the coming years, namely the use of other administrative measures short of detention, particularly assigned residence, and detentions carried out by armed groups that are supported by foreign States.
Sweeping Effects Modify Taylor’s Frozen Turbulence Hypothesis for Scalars in the Roughness Sublayer
Authors: Everard K. A. , Katul G. G. , Lawrence G. A. , Christen A. , Parlange M. B. 
Published: October 2021

AbstractTaylor’s frozen turbulence hypothesis (FTH) is investigated in the roughness sublayer of a sloped vineyard canopy using a spatial array of fine‐wire thermocouples and ultrasonic anemometers. The Ellipse Approximation (EA) method is applied to the measured space‐time temperature correlation function to delineate sweeping effects from advection velocity. Sweeping effects are explained primarily by the turbulence kinetic energy. Upon the removal of sweeping effects, the advection velocity is found to be commensurate with the mean velocity.