bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of organic matter on soil hydrothermal processes in the Tibetan Plateau: Observation and parameterization
Authors: Sun Jing , Chen Yingying , Yang Kun , Lu Hui , Zhao Long , Zheng Donghai 
Published: August 2021

AbstractIn the central-eastern Tibetan Plateau (TP) there is abundant organic matter in topsoils, which plays a crucial role in determining soil hydraulic properties that need to be properly described in land surface models. Limited soil parameterizations consider the impacts of soil organic matter (SOM), but they still show poor performance in the TP. A dedicated field campaign is therefore conducted by taking undisturbed soil samples in the central TP to obtain in-situ soil hydraulic parameters and to advance SOM parameterizations. The observed findings are twofold. 1) The SOM pore-size distribution parameter, derived from measured soil water retention curves, has been demonstrated to be much underestimated in previous studies. 2) SOM saturated hydraulic conductivity is overestimated. Accordingly, a new soil hydraulic parameterization is established by modifying a commonly used one based on observations, which is then evaluated by incorporating it into Noah-MP. Compared with the original ones, the new parameterization significantly improves surface soil liquid water simulations at stations with high surface SOM content, especially in the warm season. A further application with the revised Noah-MP indicates that SOM can enhance sensible heat flux but decrease evaporation and subsurface soil temperature in the warm season, and tends to have a much weak effect in the cold season. This study provides insights into the role of SOM in modulating soil state and surface energy budget. Note that, however, there are many other factors at play and the new parameterization is not necessarily applicable beyond the TP.
A machine learning approach for classifying bird and insect radar echoes with S-band Polarimetric Weather Radar
Authors: Jatau Precious , Melnikov Valery , Yu Tian-You 
Published: August 2021

AbstractThe S-bandWSR-88D weather radar is sensitive enough to observe biological scatterers like birds and insects. However, their non-spherical shapes and frequent collocation in the radar resolution volume create challenges in identifying their echoes. We propose a method of extracting bird (or insect) features by coherently averaging dual polarization measurements from multiple radar scans, containing bird (insect) migration. Additional features are also computed to capture aspect and range dependence, and the variation of these echoes over local regions. Next, ridge classifier and decision tree machine learning algorithms are trained, first only with the averaged dual pol inputs and then different combinations of the remaining features are added. The performance of all models for both methods, are analyzed using metrics computed from the test data. Further studies on different patterns of birds/insects, including roosting birds, bird migration and insect migration cases, are used to further investigate the generality of our models. Overall, the ridge classifier using only dual polarization variables was found to perform consistently well across all these tests. Our recommendation is that this classifier can be used operationally on the US Next-Generation Radars (NEXRAD), as a first step in classifying biological echoes. It would be used in conjunction with the existing Hydrometeor Classification Algorithm (HCA), where the HCA would first separate biological from non-biological echoes, then our algorithm would be applied to further separate biological echoes into birds and insects. To the best of our knowledge, this study is the first to train a machine learning classifier that is capable of detecting diverse patterns of bird and insect echoes, based on dual polarization variables at each range gate.
Critical insurance studies: Some geographic directions
Authors: Booth Kate 
Published: August 2021

Critical insurance studies recognises insurance as not purely actuarial and calculative. From this recognition, this theoretically informed research pays attention to the reproduction of power in insurantial discourse and practice, and possibilities for equitable change. To extend geographical contributions in this regard, I review critical insurance research and describe three intersecting foci – governmentality, materiality and spatiality. I also contribute new insights in considering insurance as co-constituting fluid and fire space – as flowing and adapting within everyday complexities, and as fiery and constituted through multiple flickering realities. These contestable multiplicities and mobilities may contribute to more equitable configurations beyond the hegemonic.
Understanding Physical Activity Patterns Across the School Day in Urban Pre-Kindergarten and Elementary Schoolchildren
Authors: Sacheck Jennifer M. , Blake Emily F. , Press Hannah , Huang Qiushi , Wright Catherine M. , Lora Karina R. , Sylvetsky Allison C. , Visek Amanda J. , DiPietro Loretta 
Published: August 2021

Purpose: Despite recommendations that children accrue ≥60 min/day of moderate-to-vigorous physical activity (MVPA), numerous barriers may exist. We examined school-day MVPA patterns in lower-income children (pre-K to 5th grade) to determine whether they were meeting the minimum school-day guidelines of at least 30-min/day of MVPA and to identify opportunities for intervention. Methods: Students (N = 629, pre-K-5th grade) from 4 urban schools wore Actigraph GT3X+ accelerometers over 2 school days. Mixed effects models evaluated sex- and grade-specific differences in MVPA and sedentary time. Results: Only 34.6% of elementary and 25.3% of pre-K students met the school-time MVPA recommendation. Among elementary-aged children, boys accrued more MVPA than girls (30.8 ± 13.3 vs. 23.5 ± 10.7 min/day; p < 0.0001) with similar sex differences observed among pre-K children (51.3 ± 17.1 vs 41.9 ± 17.5 min/day; p < 0.001). Sedentary time also increased significantly with grade among elementary-aged children (207.9 ± 34.7 vs. 252.0 ± 36.1 min/day for those in 1st and 5th grade, respectively; p < 0.001), with girls accruing more sedentary time than boys (242.5 ± 48.2 vs. 233.8 ± 46.8 min/day; p < 0.0001). Conclusion: MVPA declines across elementary school years, with sex disparities observed as early as pre-K. Extended sedentary bouts and clustering of activity highlight opportunities for more movement throughout the school day.
Talar Dome Access Through Posteromedial Surgical Intervals for Fracture Care
Authors: DeKeyser Graham J. , O’Neill Dillon C. , Sripanich Yantarat , Lenz Amy L. , Saltzman Charles L. , Haller Justin M. , Barg Alexej 
Published: August 2021

Background: Posterior talar body fractures are rare injuries without a consensus surgical approach. This study evaluates the accessible area of the talar dome through 2 posteromedial approach intervals (posteromedial [PM] and modified posteromedial [mPM]) both with and without distraction. Methods: Ten male cadaveric legs (5 matched pairs) were included. A PM approach, between flexor hallucis longus (FHL) and the tibial neurovascular bundle, and an mPM approach, between FHL and Achilles tendon, was performed on each pair. In total, 4 mm of distraction across the tibiotalar joint was applied with the foot held in neutral position. Accessible dome surface area (DSA) was outlined by drilling with a 1.6-mm Kirschner wire with and without distraction. Specimens were explanted and analyzed by micro–computed tomography with 3-dimensional reconstruction. Primary outcomes were total accessible DSA and sagittal plane access at predetermined intervals. Results: The PM approach allowed access to 19.1% of the talar DSA without distraction and 33.1% of the talar dome with distraction ( P < .001). The mPM approach provided access to 20.4% and 35.6% of the talar DSA without and with distraction ( P < .001). Both approaches demonstrated similar sagittal plane access at all intervals except the lateral border of the talus, where the mPM approach provided greater access both without distraction (20.5% vs 4.38%, P = .002) and with distraction (34.3% vs 17.8%, P = .02). Conclusion: The mPM approach, using an interval between FHL and Achilles tendon, provides similar access to the posterior surface of talar dome and better sagittal plane access to the most lateral portion of the dome. The mPM interval provides the advantage of avoiding direct dissection of the tibial nerve or posterior tibial artery. Using an external fixator for distraction can improve talar dome visualization substantially. Level of Evidence: Level V, Cadaveric Study.
Serum IL-6/IL-10 ratio as a biomarker for the diagnosis and severity assessment of primary-open angle glaucoma
Authors: Ulhaq Zulvikar Syambani , Soraya Gita Vita , Hasan Yuliono Trika Nur , Rachma Lailia Nur , Rachmawati Ermin , Shodry Syifaus , Kusuma Muhammad A’raaf Sirojan 
Published: August 2021

Objective: To assess the performance of serum cytokine IL-6 and IL-6/IL-10 ratio as biomarkers for the diagnosis of primary open-angle glaucoma (POAG) and for determining its progression. Methods: In this study, 20 POAG patients and 21 healthy individuals from the Indonesian population were enrolled. The serum concentration of IL-6 and IL-10 were quantified. Comparative analysis was performed in addition to assessment of the diagnostic performance of cytokines using receiver-operating-curve (ROC) analysis. Results: POAG patients had a higher IL-6 ( p < 0.0001) and IL-6/IL-10 ratio ( p < 0.0001) than controls. Among the POAG subjects, advanced-stage patients exhibited a higher IL-6/IL-10 ratio than those in the early-moderate stage ( p = 0.001; p = 0.006). The ROC curve analysis showed that both IL-6 level and IL-6/IL-10 ratio exhibited an excellent capability of diagnosing POAG (cut-off of 20.5 pg/mL (100% sensitivity and 94% specificity) and 4.4 (88% sensitivity and 94% specificity), respectively). Serum IL-6/IL-10 ratio displayed a better performance than IL-6 in discriminating POAG severity with cut-off of at least 6.6 (sensitivity of 86% and specificity of 90%) and 9.1 (sensitivity of 89% and specificity of 78%) classified according to C/D ratio and MD of VF, respectively. Conclusion: The balance between IL-6 and IL-10 serum levels is potentially useful in discriminating POAG severity.
Multimodal imaging of bilateral immunogammopathy maculopathy associated to Waldenström’s macroglobulinemia
Authors: Bouraoui Rim , El Matri Khaled , Falfoul Yousra , Fakhfakh Dalel , Mghaieth Fatma , Chebil Ahmed , El Matri Leila 
Published: August 2021

Aim: Our aim is to report a case with bilateral Waldenström’s macroglobulinemia (WM) associated maculopathy, assessed with multimodal imaging including swept source optical coherence tomography (SS-OCT) and OCT-Angiography (OCT-A). Methods: Observational case report. Case presentation: A 61-year-old diabetic woman with history of treated WM currently in remission, presented with progressive bilateral visual loss. Best-corrected visual acuity was 20/100 in the right eye (RE) and 20/200 in the left eye (LE). Fundus examination showed bilateral microaneurysms and retinal punctuate hemorrhages and a large macular serous detachment in the LE. There was no retinal ischemia on FA nor macular dye leakage. SS-OCT showed a significant schisis-like intraretinal fluid accumulation in the RE and a large prominent macular detachment with significant subretinal fluid accumulation in the LE. Retinal and choriocapillaris vascular densities were normal on OCT-A. Conclusion: Our case illustrated characteristic multimodal imaging findings in WM associated maculopathy such as schisis-like intraretinal fluid accumulation and angiographically silent serous macular detachment. OCT-A could non-invasively analyze macular vascular densities layer-by-layer, without noticing any vascular anomaly.
Assessing ultrasound-guided axillary vein cannulation using a cumulative sum analysis: A single operator experience
Authors: Zhu Linjia , Gong Chanjuan , Zhu Jinming , Zhu Lili , Chen Liang , Ni Yan 
Published: August 2021

Background: Ultrasound-guided axillary vein (AxV) cannulation has been described as an effective alternative to internal jugular vein cannulation in adult cardiac surgical patients. However, the learning curve for this technique has not yet been addressed. This study aimed to determine the number of cases required to achieve proficiency in performing AxV cannulation among novice anesthesiologists. Methods: This prospective study included the first 60 patients who underwent ultrasound-guided AxV cannulation performed by a single third-year resident who was trained in adult cardiac anesthesia. This study investigated the number of cases required to gain technical proficiency by applying cumulative sum analysis on the learning curve (LC-CUSUM) of ultrasound-guided AxV cannulation. Results: Based on the assessment of the CUSUM plots, a descending inflection point for decreasing the overall procedural time for AxV cannulation was observed after patient 29. Regarding the procedural outcomes, comparing the early-experience group with the late-experience group (29 vs 31 cases), the former group had longer operating time (1526 s vs 1120 s, p < 0.001) and identification time (110 s vs 92 s, p < 0.001) and lower first-attempt success rate (8, 27.6% vs 30, 96.8%, p < 0.001) than the latter group. Conclusions: CUSUM demonstrated that at least 29 successful cases are required to achieve an expertized manipulation in ultrasound-guided AxV cannulation for inexperienced novices. The learning curve for ultrasound-guided AxV cannulation was observed in 29 cases. After adequate training, the overall procedural time and the first-attempt success rate, and puncture-related complications for AxV cannulation improved with increased experience.
Barriers, Enablers, and Consumer Design Ideas for Health Literacy Responsive Hospital Waiting Areas: A Framework Method Analysis
Authors: McDonald Cassie E. , Remedios Louisa J. , Cameron Kate L. , Said Catherine M. , Granger Catherine L. 
Published: August 2021

Aim: The study aim was to (1) investigate the barriers and enablers experienced by consumers to accessing and engaging with health tools in hospital waiting areas and (2) evaluate consumers’ ideas for designing a health literacy responsive waiting area. Background: Health information, resources, and supports (“health tools”) in waiting areas should be responsive to the health literacy needs of consumers. However, consumers’ experiences of using health tools and their ideas for improving them are not known. Methods: Multicenter study was set in hospital waiting areas of outpatient rehabilitation services. Semistructured in-person interviews were conducted with 33 adult consumers attending appointments for various health conditions. Seven stages of the Framework Method were used to analyze data. Results: Six themes were identified which explained barriers and enablers from the perspective of consumers. The barriers were accessibility issues; personal factors—physical condition, emotional state, and preferences; and poorly presented and outdated resources. The enablers were design suits consumer needs and preferences; usable in available time or portable; and compatible environment for engaging and sharing. Consumers shared design ideas which fit within four typologies. Conclusions: A range of barriers and enablers exist which have an impact on consumers’ ability to engage with available health information, resources, and supports in hospital outpatient waiting areas. Practical insights from the perspective of consumers can be applied to future health service design. Consumer’s design ideas suggest that partnerships with consumers should be formed to design health literacy responsive waiting areas.
Serum fatty acids profile and association with early-onset coronary artery disease
Authors: Xuan Chao , Tian Qing-Wu , Li Hui , Guo Jun-Jie , He Guo-Wei , Lun Li-Min 
Published: August 2021

Background: Fatty acids (FAs) play crucial roles in modulating and preventing diseases in humans, including early-onset coronary artery disease (EOCAD). In this study, we aimed to provide a profile of FAs in the serum of EOCAD patients and identify potential EOCAD-associated FAs. Methods: In the first stage, we analyzed the FAs profiles in pooled samples of patients with EOCAD using gas chromatography-mass spectrometry. In the second stage, the serum levels of the candidate FAs were validated in EOCAD patients. Results: A total of 128 EOCAD patients and 64 controls were included in the study. Forty-nine serum FAs were quantified in pooled samples; three ω-3 FAs were identified to be associated with EOCAD. Moreover, results from the validation stage indicated that serum levels of docosahexaenoic acid (DHA) were significantly lower in EOCAD patients (55.43 ± 33.86 µg/ml) and myocardial infarction (MI) patients (47.49 ± 28.44 μg/ml) than those in the controls (70.65 ± 43.56 µg/ml). Multivariate regression analysis revealed that elevated serum DHA level was an independent protective factor for EOCAD [odds ratio (OR) = 0.8917, 95% confidence interval (CI): 0.879–0.957] and MI (OR = 0.835, 95% CI: 0.799–0.862). Decreased serum levels of docosapentaenoic acid (DPA) and eicosapentaenoic acid (EPA) were observed in the early-onset MI group. Conclusion: The study provided the serum FAs profile of EOCAD and confirmed that the decrease in serum levels of DHA, DPA, and EPA was associated with EOCAD. These findings might contribute to understanding the cardiovascular effects of FAs, particularly the protective effects of ω-3 polyunsaturated FAs.
Prognostic indicators of survival in patients with small-cell lung cancer at a tertiary care center in Lebanon
Authors: Tfayli Arafat , Atwi Hanine , Naji Amal , Assaad Majd Al , Assi Sahar , Hazimeh Maya 
Published: August 2021

Objective: Small-cell lung cancer is a very aggressive tumor associated with high invasiveness and ease of metastasis and therefore poor prognosis. In the literature, several demographical, clinical as well as pathological factors including age, stage, gender and smoking were cited as independent prognosticators of survival. Material and Methods: This is a retrospective cohort study that includes 222 patients diagnosed with small-cell lung cancer between 2010 and 2019. Clinical and demographic data were extracted from their medical records. The Kaplan–Meier and logistic regression models of statistical analysis were used to evaluate the association of these variables with survival. Results: Forty-five percent of patients were found to be alive at the time of data collection. The median survival of patients with small-cell lung cancer was found to be 14 months. On univariate analysis, increasing age as well as stage (extensive disease) were found to be significantly associated with decreased survival at 3 years. On the contrary, both gender and smoking status at diagnosis were not shown to significantly influence survival. On multivariate analysis, both age as well as stage remained significantly associated with survival. Conclusion: Limited data exist in the literature regarding the prognostic indicators of survival in small-cell lung cancer, especially from the Middle East area. In our study, both age and stage at the time of diagnosis were found to significantly influence survival. Further studies are needed to assess the association of other factors with survival.
Essential amino acid supplementation is associated with reduced serum C-reactive protein levels and improved circulating lymphocytes in post-acute inflamed elderly patients
Authors: Aquilani Roberto , Zuccarelli Ginetto C , Maestri Roberto , Boselli Mirella , Dossena Maurizia , Baldissarro Eleonora , Boschi Federica , Buonocore Daniela , Verri Manuela 
Published: August 2021

Background Persistent systemic inflammation leads to multidistrectual body dysfunctions. Attenuation of inflammation may improve patients’ functional and life prognoses. We hypothesized that essential amino acids (EAAs) given to elderly patients in rehabilitation after acute diseases may be associated with a reduced inflammatory state. Therefore, this retrospective study investigated whether the supplementation of EAAs – modulators of immune competence – was associated with a reduced inflammation rate in elderly patients. Methods The medical records of 282 patients admitted to the rehabilitation (rehab) institute after acute index events (surgery or medical diseases) (age: 81.18 ± 8.58 years; females: 67.9%) were analyzed. Results 46 patients (16.3% of the entire population) had received EAA supplements (S), whereas the remaining 236 patients had not (N-S). Systemic inflammation (I) (serum C-reactive protein (CRP) > 0.5 mg/dL) was present in 67.4% of the I-S group and 57.2% of the I-N-S group. During rehab, the I-S group (but not the I-N-S group) showed a reduction in CRP levels ( p = 0.03) and an increase in circulating lymphocytes ( p = 0.035), immune cells of the adaptive immune system. C-reactive protein levels remained virtually unchanged in non-inflamed patients who received supplements but increased in non-inflamed patients who did not receive supplements ( p = 0.05). Stratified for developed infections, CRP levels reduced in S patients ( p = 0.008) but did not in N-S patients. Conclusion EAA supplementation was associated with reduced inflammation in both inflamed and infected patients. In addition, EAA supplementation was associated with increased circulating lymphocytes in inflamed patients.