bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Gender Backlash in the Vote for Brexit
Authors: Green Jane , Shorrocks Rosalind 
Published: April 2021

AbstractDespite a relationship between gender and support for populist causes in cross-national research, including in the 2016 US Presidential election, the role of gender has been missing in analysis of support for Brexit, most likely because women and men showed no average aggregate-level differences in voting Leave or Remain. This misses an important explanation for Britain’s vote to leave the European Union. We demonstrate how gender-based resentment motivated Leave votes in the EU referendum through perceptions of discrimination against men, among men. Using novel survey measures, we demonstrate (i) the distinct nature of perceptions of discrimination towards men in comparison with discrimination towards women; (ii) the sociological sources of perceptions that men are discriminated against; and (iii) the role of these perceptions in Brexit support. Our findings reveal that the Brexit referendum provided an opportunity to express broader social grievances than have, to date, been identified as relevant. The paper therefore offers a novel contribution to understanding the cultural backlash behind Britain’s vote to leave the EU, and by so doing, insight into the potential for gender-based backlash effects in elections where gender isn’t significantly primed, unlike the 2016 US presidential election where gender was a major political focus.
Validation of snoring detection using a smartphone app
Authors: Chiang Jui-Kun , Lin Yen-Chang , Lin Chih-Wen , Ting Ching-Shiung , Chiang Yi-Ying , Kao Yee-Hsin 
Published: April 2021

Abstract
Purpose
Snoring is closely related to obstructive sleep apnea in adults. The increasing abundance and availability of smartphone technology has facilitated the examination and monitoring of snoring at home through snoring apps. However, the accuracy of snoring detection by snoring apps is unclear. This study explored the snoring detection accuracy of Snore Clock—a paid snoring detection app for smartphones.

Methods
Snoring rates were detected by smartphones that had been installed with the paid app Snore Clock. The app provides information on the following variables: sleep duration, snoring duration, snoring loudness (in dB), maximum snoring loudness (in dB), and snoring duration rate (%). In brief, we first reviewed the snoring rates detected by Snore Clock; thereafter, an ear, nose, and throat specialist reviewed the actual snoring rates by using the playback of the app recordings.

Results
In total, the 201 snoring records of 11 patients were analyzed. Snoring rates measured by Snore Clock and those measured manually were closely correlated (r = 0.907). The mean snoring detection accuracy rate of Snore Clock was 95%, with a positive predictive value, negative predictive value, sensitivity, and specificity of 65% ± 35%, 97% ± 4%, 78% ± 25%, and 97% ± 4%, respectively. However, the higher the snoring rates, the higher were the false-negative rates for the app.

Conclusion
Snore Clock is compatible with various brands of smartphones and has a high predictive value for snoring. Based on the strong correlation between Snore Clock and manual approaches for snoring detection, these findings have validated that Snore Clock has the capacity for at-home snoring detection.
Development of a Novel Ni-Based Multi-principal Element Alloy Filler Metal, Using an Alternative Melting Point Depressant
Authors: Hardwick Liam , Rodgers Pat , Pickering Ed , Goodall Russell 
Published: April 2021

AbstractBrazing is a crucial joining technology in industries where nickel-superalloy components must be joined. Nickel-based brazing filler metals are extensively employed, possessing excellent mechanical properties, corrosion resistance, and retained strength at elevated temperatures. To function as a filler metal, the alloy melting point must be reduced to below that of the materials being joined, but the addition of melting point depressants (MPDs) such as boron, silicon, and phosphorus can, however, lead to the formation of brittle intermetallics, potentially compromising the joint performance. In the present work, a novel multi-principal element brazing alloy (in the style of a high entropy alloy), utilizing Ge as an alternative MPD along with a reduced B addition, is investigated. The design process considered binary phase diagrams and predictions based on Thermo-Calc software and empirical thermodynamic parameters. The alloy was used to vacuum braze nickel-superalloy Inconel-718, and microstructural and mechanical investigations are reported. The maximum shear strength achieved was 297 MPa with a brazing temperature of 1100 °C and 60-minute hold time, with isothermal solidification completed. Shear strength was only slightly reduced with increased joint width. Assessments are made of the ability to accurately predict properties of multi-principle element alloys using Thermo-Calc software and empirical thermodynamic parameters.
Measuring the social performance of forest management
Authors: Pukkala Timo 
Published: April 2021

AbstractForests produce several types of benefits to both forest landowners and society. The social benefit of private forestry is equal to private benefit plus positive externalities minus negative externalities. This study developed alternative metrics for the evaluation of the social benefit of forest management. Forest management was assessed in terms of five criteria: economic, socio-cultural, environmental and ecological performance and the resilience of the forest ecosystem. Each criterion was described with three numerical indicators. Alternative performance indices were calculated from the indicator values using methods developed for multi-criteria decision making. It was concluded that indices based on the multiplicative Cobb–Douglas utility function might be the most recommendable when forestry should produce a balanced combination of different ecosystem services. When the indices were used to compare alternative silvicultural systems in terms of their social performance, continuous cover management was ranked better than even-aged management. The performance of even-aged management improved when it aimed at increasing the share of mixed stands and broadleaf species. Maximizing net present value (NPV) with a 1% discount rate led to better social performance than maximizing NPV with a 4% discount rate.
A Survey on How Ocular Surface Demodex Infestation Interactively Associates with Diabetes Mellitus and Dry Eye Disease
Authors: Huang Chang , Chen Shuze , Fu Sheng , Li Yingli , Li Zhenhao , Li Siqi , Liang Xiaoqian , Wang Zihong , Wang Zhoucheng , Chen Yifan , Deng Qixin , Yi Guoguo , Fu Min 
Published: April 2021

Abstract
Purpose
Prevention of ocular surface (OS) Demodex infestation plays an important role in OS hygiene and variety of factors may be associated with it, in which diabetes mellitus (DM) or dry eye disease (DED) has caught the attention of most scholars. However, there has been no research on whether there was a potential interaction between DM and DED in the process of OS Demodex infestation. This cross-sectional study was implemented in Zhujiang Hospital of Southern Medical University.

Methods
Ophthalmologic interviews, questionnaires, and examinations were conducted. Factors including general information, DM status, dry eye condition, etc. were collected to study the correlation of DM and DED on OS Demodex infestation.

Results
After statistical analysis, we found that both DM (P < 0.001) and DED (P = 0.013 < 0.05) are closely associated with OS Demodex infestation. Compared with DED, DM has higher priority association with OS Demodex infestation, and patients with both diseases have a significant higher risk of OS Demodex infestation (R = 0.197, P < 0.001). Meanwhile, age (R = 0.299, P < 0.001) and hypertension (P < 0.05) were also correlated with OS Demodex infestation.

Conclusion
This study provides a new evidence-based basis for clinical prevention and management of OS Demodex infestation.
Depression and hypertension awareness, treatment, and control in a multiethnic population in the Netherlands: HELIUS study
Authors: Fernald Florence , Snijder Marieke , van den Born Bert-Jan , Lok Anja , Peters Ron , Agyemang Charles 
Published: April 2021

AbstractIndividuals belonging to ethnic minority groups are more susceptible to depression and comorbid hypertension than European host populations. Yet, data on how depression is related to hypertension in ethnic groups in Europe are lacking. Therefore, we studied the association between significant depressed mood (SDM) and hypertension prevalence, awareness, treatment, and control among ethnic groups. Data from the HELIUS study included 22,165 adults (aged 18–70) from six ethnic backgrounds in the Netherlands. Logistic regression analysis was used to explore the association between SDM and hypertension prevalence, awareness, treatment, and control with adjustment for age, sex, and for sensitivity analysis purposes also for anti-depressants. After adjustment for age and sex, Dutch with SDM had an increased odds of hypertension (OR 95% CI 1.67; 1.08–2.59). Among Turkish, SDM was associated with higher odds of hypertension awareness (2.09; 1.41–3.09), treatment (1.92; 1.27–2.90) and control (1.72; 1.04–2.83). Among Moroccans, SMD was associated with an increased odds of hypertension awareness (1.91; 1.14–3.21) but decreased odds of hypertension control (0.42; 0.20–0.89). Additional adjustment for anti-depressant medications did not change the results. There were no associations between SDM and hypertension, awareness, treatment and control in South-Asian Surinamese, African Surinamese and Ghanaian participants. The results underline significant differences in the association between SDM and hypertension awareness, treatment and control between ethnic groups. Our findings emphasize the necessity to further study ethnicity-related factors that may influence the association between SDM and hypertension to promote hypertension control especially, among Moroccans with SDM.
Carbon-ion radiotherapy subsequent to balloon-occluded retrograde transvenous obliteration for hepatocellular carcinoma with hepatic encephalopathy: a multidisciplinary approach
Authors: Osu Naoto , Shiba Shintaro , Shibuya Kei , Okazaki Shohei , Miyasaka Yuhei , Okamoto Masahiko , Ohno Tatsuya 
Published: April 2021

AbstractRadical treatments of hepatocellular carcinoma (HCC) with hepatic encephalopathy (HE) can be often difficult due to poor liver function or disturbance of consciousness. An effective treatment requires a combinatorial approach incorporating a treatment for HE and radical therapy for HCC that does not compromise liver function. Here, we report a case of a 78-year-old Japanese male with HCC and HE caused by splenorenal shunt. Serum ammonia levels were high. He was not suitable for surgery, percutaneous radiofrequency ablation, or transarterial chemoembolization due to the location of the tumor and poor liver function, which included HE. Thus, he underwent BRTO, with an immediate improvement in both HE and serum ammonia levels. After BRTO, he received C-ion RT as a radical treatment for HCC. After treatment, HCC was well controlled; however, at 35 months post-initiation of C-ion RT, he developed local recurrence without a further reduction in liver function status. Therefore, we repeated C-ion RT. The patient remains alive at 3 months post-treatment, with no evidence of local recurrence, distant metastasis, or toxicity. Although this is a single case report, it suggests that a combinatorial treatment consisting of BRTO and C-ion RT may increase survival rates of patients with HCC and HE.
Kinetics and isotherm modeling of Pb(II) and Cd(II) sequestration from polluted water onto tropical ultisol obtained from Enugu Nigeria
Authors: Umeh Theresa C. , Nduka John K. , Akpomie Kovo G. 
Published: April 2021

AbstractDeterioration in soil–water environment severely contributed by heavy metal bioavailability and mobility on soil surface and sub-surface due to irrational increase in wastewater discharge and agrochemical activities. Therefore, the feasibility of adsorption characteristics of the soil is paramount in curbing the problem of micropollutant contamination in the farming vicinity. Soil from a farming site in a populated area in Enugu, Nigeria was collected and tested to measure the lead and cadmium contents using atomic absorption spectrophotometer (AAS). The adsorption potency of the ultisol soil was estimated for identifiable physicochemical properties by standard technique. The mean activity concentration of Pb2+and Cd2+was 15.68 mg/kg and 3.01 mg/kg. The pH, temperature, metal concentration and contact time adsorptive effect on the Pb2+and Cd2+uptake was evaluated by batch adsorption technique. The Langmuir, Freundlich and Temkin models were fitted into equilibrium adsorption data and the calculated results depict a better and satisfactory correlation for Langmuir with higher linear regression coefficients (Pb2+, 0.935 and Cd2+, 0.971). On the basis of sorption capacity mechanism of the soil, pseudo-second-order model best described the kinetics of both metal ions retention process. The results of the present study indicated that the soil being a low cost-effective adsorbent can be utilized to minimize the environmental risk impact of these metal ions.
Serum concentrations of dihydrotestosterone are associated with symptoms of hypogonadism in biochemically eugonadal men
Authors: Sansone A. , Kliesch S. , Dugas M. , Sandhowe-Klaverkamp R. , Isidori A. M. , Schlatt S. , Zitzmann M. 
Published: April 2021

Abstract
Purpose
Symptoms of hypogonadism are often reported by subjects with normal serum testosterone (T) levels. We aimed to assess the association between clinical symptoms in andrological outpatients and sex steroids levels.

Methods
This is a retrospective cross-sectional cohort study in an Academic clinic and research unit. International Index of Erectile Function (IIEF, EF domain) and Aging Males Symptoms scale (AMS) questionnaires were completed by 635 and 574 men, respectively (mean age: 47.3 ± 13.9 and 47.4 ± 13.8 years, p = 0.829), free of interfering medications with complaints possibly related to hypogonadism.

Results
Serum total/free T as well as dihydro-T (DHT) was associated with IIEF-EF and AMS scores in the overall population using univariate analyses. Multivariate approaches revealed DHT concentrations in subjects with normal T levels (n = 416, Total T > 12 nmol/L) to be significant predictors of AMS scores. A 0.1 nmol/l serum DHT increase within the eugonadal range was associated with a 4.67% decrease in odds of having worse symptoms (p = 0.011). In men with biochemical hypogonadism (Total T < 12 nmol/L), total and free T rather than DHT were associated with AMS results. This association was not found for IIEF-EF scores. Indirect effects of age and BMI were seen for relations with hormone concentrations but not questionnaire scores.

Conclusion
DHT can be associated with symptoms of hypogonadism in biochemically eugonadal men. Serum DHT measurement might be helpful once the diagnosis of hypogonadism has been ruled out but should not be routinely included in the primary diagnostic process.
EEG data augmentation for emotion recognition with a multiple generator conditional Wasserstein GAN
Authors: Zhang Aiming , Su Lei , Zhang Yin , Fu Yunfa , Wu Liping , Liang Shengjin 
Published: April 2021

AbstractEEG-based emotion recognition has attracted substantial attention from researchers due to its extensive application prospects, and substantial progress has been made in feature extraction and classification modelling from EEG data. However, insufficient high-quality training data are available for building EEG-based emotion recognition models via machine learning or deep learning methods. The artificial generation of high-quality data is an effective approach for overcoming this problem. In this paper, a multi-generator conditional Wasserstein GAN method is proposed for the generation of high-quality artificial that covers a more comprehensive distribution of real data through the use of various generators. Experimental results demonstrate that the artificial data that are generated by the proposed model can effectively improve the performance of emotion classification models that are based on EEG.
Urinary 1-aminopyrene level in Koreans as a biomarker for the amount of exposure to atmospheric 1-nitropyrene
Authors: Ochirpurev Bolormaa , Eom Sang-Yong , Toriba Akira , Kim Yong-Dae , Kim Heon 
Published: April 2021

Abstract1-Nitropyrene (1-NP) is a major nitro-polycyclic aromatic hydrocarbon (nitro-PAH), and a common constituent in diesel exhaust particles (DEPs). Absorbed 1-nitropyrene is partly metabolized to 1-aminopyrene and excreted in urine. Recently, the number of diesel cars has been increasing, which could be a major cause of air pollution, resulting elevated levels of traffic-related DEPs around cities. The aim of this study was to investigate the usability of 1-aminopyrene (1-AP) as a biomarker for DEP exposure by examining the association between urinary 1-AP concentration and the amount of exposure to atmospheric 1-NP. The study subjects included 65 individuals who work on vehicular roads or bus terminals. Their 24 h urine samples were collected, and atmospheric air was sampled using a personal air sampler for 24 h. Urinary 1-AP and atmospheric nitro-PAH levels were measured using a high-pressure liquid chromatography-fluorescence detector (HPLC-FD). The average urine 1-AP concentration was 0.334 pg/g creatinine. Urinary 1-AP levels were significantly correlated with 1-NP level exposure (r = 0.385, p = 0.002) but not with the other nitro-PAHs. When the subjects were classified into high-and low-exposure groups, a significant association was only found in the high exposure group (r = 0.357, p = 0.045). In conclusion, there was a significant correlation between 1-NP exposure and urinary 1-AP concentration; therefore, urinary 1-AP level could be used as an exposure biomarker for DEP.
Energy-Water-Environment Nexus and the Transition Towards a Circular Economy: The Case of Qatar
Authors: Ibrahim Abdul-Jalil , Shirazi Nasim Shah 
Published: April 2021

Abstract
Background
Qatar’s per capita consumption of both energy and water is among the highest in the world. Documentation of methods to reduce energy and water use and its impact on the environment is crucial. A circular economy (CE) ensures that economic growth must not necessarily lead to more resource consumption.

Materials and methods
This study aims to discuss the CE approach with a focus on understanding the interdependencies between energy and water and their impact on the environment. The study explores the energy-water-environment nexus and how Qatar can leverage this to transition to a CE. The policy landscape and strategies related to energy and water use sectors are presented, addressing efficiencies and substitutes from a circular economic viewpoint.

Results
The findings show that electricity and mobility sectors(energy perspective of the CE) and agriculture and water supply system (water perspective of the CE) of the Qatari economy provide an opportunity for regeneration, virtualising, exchanging, optimising, sharing and closing loops to achieve CE growth.

Conclusions
The nexus between the mobility, electricity, agriculture and water supply system needs consideration for optimal policy outcome for the CE in Qatar. The study recommends a need to embark on public awareness on moving away from linear economic to the circular economic paradigm and developing a comprehensive policy on Qatar’s circular economic approach that consolidates the Qatar National Vision 2030 and the National Development Strategy 2018–2022 to provide policy clarity and communication towards CE.
Assessment of music experience after cochlear implantation: A review of current tools and their utilization
Authors: Hwa Tiffany P. , Wen Christopher Z. , Ruckenstein Michael J. 
Published: April 2021

ObjectiveTo provide an overview of the current available music assessment tools after cochlear implantation (CI); to report on the utilization of music assessments in the literature; to propose potential future directions in music assessment after CI.MethodsA thorough search was performed in PubMed, Embase, and The Cochrane Library through October 31, 2020. MeSH search terms, keywords, and phrases included “cochlear implant,” “cochlear prosthesis,” “auditory prosthesis,” “music,” “music assessment,” “music questionnaire,” “music perception,” “music enjoyment, and “music experience.” Potentially relevant studies were reviewed for inclusion, with particular focus on assessments developed specifically for the cochlear implant population and intended for widespread use.Results/conclusionsSix hundred and forty‐three studies were screened for relevance to assessment of music experience among cochlear implantees. Eighty‐one studies ultimately met criteria for inclusion. There are multiple validated tools for assessment of music experience after cochlear implantation, each of which provide slightly differing insights into the patients’ subjective and/or objective post‐activation experience. However, no single assessment tool has been adopted into widespread use and thus, much of the literature pertaining to this topic evaluates outcomes non‐uniformly, including single‐use assessments designed specifically for the study at hand. The lack of a widely accepted universal tool for assessment of music limits our collective understanding the contributory and mitigating factors applicable to current music experience of cochlear implantees, and limits our ability to uniformly evaluate the success of new implant technologies or music training paradigms.
Institutional analysis of intra‐ and post‐operative tracheostomy management for risk reduction
Authors: Henry Laura E. , Paul Ellen A. , Atkins Joshua H. , Martin Niels D. , Chalian Ara A. , Rassekh Christopher H. 
Published: April 2021

AbstractObjectivesDetermine variability in intra‐ and post‐operative management of tracheostomies (trachs) at our institution as existing literature suggests that trachs are a frequent trigger for airway‐related emergencies. Catalyze the development of an institution‐wide protocols for trach care.MethodsA 39‐question online survey was sent to 55 providers who perform open and percutaneous trachs at three of the hospitals within our large, urban, academic medical center. These providers were identified by surveillance of the operating room schedules for 1 year.ResultsThe survey was completed by 40 of the 53 eligible providers (75.5%). Response rate by question varied. Respondents included members of all departments that perform trachs at our institution (Otorhinolaryngology, Trauma Surgery, Thoracic Surgery, General Surgery, Cardiovascular Surgery and Interventional Pulmonology).While most responses demonstrated uniformity in practice, notable variations included the following: 80% of percutaneous trach providers stated that morbid obesity was not a contraindication to performing a trach outside of the operating room (n = 20) while 58% of open trach providers stated that morbid obesity was a contraindication; only 35% of open trach providers perform a Bjork flap (n = 350). The survey also identified significant variability in practice with regards to timing of trach suture removal.DiscussionLack of uniformity was identified in several practices related to intra‐ and post‐operative tracheostomy care. Results did, however, trend toward consensus in many areas. The results are being used to establish a more consistent approach to tracheostomy management across our institution to ensure standardization of practice amidst the rapidly evolving practices of trach placement.Implications for practiceWith ongoing evolution in the methods of trach placement and its management, the concepts put forth here will be a resource for health care providers at other institutions to consider intra‐institutional analysis and establishment of practice standardization.