bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rapid construct superhydrophobic microcracks on the open-surface platform for droplet manipulations
Authors: Lin Wan-Shiuan , Chen Chien-Wei , Wang Sheng-Hang , Li Bor-Ran 
Published: May 2021

Abstract
Droplet-based transport driven by surface tension has been explored as an automated pumping source for several biomedical applications. This paper presented a simple and fast superhydrophobic modify and patterning approach to fabricate various open-surface platforms to manipulate droplets to achieve transport, mixing, concentration, and rebounding control. Several commercial reagents were tested in our approach, and the Glaco reagent was selected to create a superhydrophobic layer; laser cutters are utilized to scan on these superhydrophobic surface to create gradient hydrophilic micro-patterns. Implementing back-and-forth vibrations on the predetermined parallel patterns, droplets can be transported and mixed successfully. Colorimetry of horseradish peroxidase (HRP) mixing with substrates also reduced the reaction time by more than 5-times with the help of superhydrophobic patterned chips. Besides, patterned superhydrophobic chips can significantly improve the sensitivity of colorimetric glucose-sensing by more than 10 times. Moreover, all bioassays were distributed homogeneously within the region of hydrophilic micropatterns without the coffee-ring effect. In addition, to discuss further applications of the surface wettability, the way of controlling the droplet impacting and rebounding phenomenon was also demonstrated. This work reports a rapid approach to modify and pattering superhydrophobic films to perform droplet-based manipulations with a lower technical barrier, higher efficiency, and easier operation. It holds the potential to broaden the applications of open microfluidics in the future.
Earth's balanced climates in view of their energy budgets
Authors: Anderl Thomas 
Published: May 2021

Abstract
Earth’s well-known energy budget scheme is subjected to variations representing changes of insolation and atmospheric absorption. The Charney Report variability cases of doubled atmospheric CO2 concentration and insolation increase by 2 % are found reproducible. The planetary emissivity is revealed linear to surface temperature, conformant with measurements. Atmospheric water vapor with its characteristic concentration-temperature dependency appears as a major component in Earth’s energy balancing mechanisms. From this, shift towards fewer and stronger rainfall events is prescribed for rising temperatures.
Development of methods for determining the coordinates of firing positions of roving mortars by a network of counter-battery radars
Authors: Khudov Hennadii , Yuzova Iryna , Lisohorskyi Bohdan , Solomonenko Yuriy , Mykus Serhii , Irkha Artem , Onishchuk Volodymyr , Sukonko Serhii , Semiv Galina , Bondarenko Semen 
Published: May 2021

The mathematical formulation of the problem of determining the coordinates of targets in the network of counter-battery radars is formulated. It has been established that the problem of estimating the coordinates of targets in the network of counter-battery radars for an excessive number of estimates of primary coordinates should be considered as a statistical problem. The method for determining the coordinates of the firing positions of roving mortars has been improved, in which, in contrast to the known ones, the coordinates of targets on the flight trajectory are coordinated with space and time and the information is processed by a network of counter-battery radars. The developed simulation mathematical model for determining the coordinates of the firing positions of roving mortars by a network of counter-battery radars. Simulation modeling of the method for determining the coordinates of the firing positions of roving mortars by a network of counter-battery radars has been carried out. It has been established that the use of a network of radars makes it possible to increase the accuracy of determining the coordinates of the firing means on average from 23 % to 71 %, depending on the number of counter-battery radars in the network. It has also been found that the appropriate number of counter-battery warfare radars in the network is three or four. A further increase in the number of counter-battery warfare radars in the network does not lead to a significant increase in the accuracy of determining the coordinates of artillery and mortar firing positions. In carrying out further research, it is necessary to develop a method for the spatial separation of elements of a group of targets and interfering objects by a network of counter-battery warfare radars
Mathematical model of the mechanical properties of Ti-alloyed hypoeutectic cast iron for mixer blades
Authors: Kharchenko Sergei , Barsuk Andriy , Karimova Nurlana , Nanka Alexander , Pelypenko Yevhen , Shevtsov Vadim , Morozov Ivan , Morozov Vladimir 
Published: May 2021

The object of research is hypoeutectic cast iron intended for cast parts operating under abrasive friction conditions. Such parts are mixer blades, the operational properties of which include durability, assessed by abrasion resistance and strength. To give the blades such properties, cast irons, which are materials of the blades, are alloyed with elements that contribute to the formation of carbides of various compositions. The main problem that impedes the targeted selection of materials for mixer blades or finished blades from different materials or different chemical composition is the lack of substantiated selection criteria. If the shipment is carried out only with the provision of data on the chemical composition of the alloy, it is necessary to be able to evaluate the expected mechanical properties, in particular abrasion resistance and strength.
Using the methods of regression analysis, a mathematical model has been obtained that includes two regression equations, which allows for a targeted selection of the chemical composition that provides the maximum possible value of mechanical properties – ultimate strength and coefficient of wear resistance. Optimization of the chemical composition, carried out according to this model, made it possible to determine the following chemical composition: C=2.94 %, Ceq=3.3 %, Ti=1.56 %, providing the maximum ultimate strength σb=391 MPa; C=2.78 %, Ceq=3.14 %, Ti=1.61 %, providing a maximum wear resistance coefficient Kwr=12 %.
In the case of priority of the strength criterion, the calculated optimal chemical composition makes it possible to reduce the mass-dimensional characteristics of the mixing units of the mixers.
A procedure is proposed for using this model to select a batch of blades with the expected best performance properties
How is the implementation of green accounting in public hospital?
Authors: Ashari Muhammad Hasyim , Anggoro Yudhi 
Published: May 2021

Purpose - The purpose of this study is to find out the implementation of green accounting in Public Hospitals in Malang and to determine the preferences of Public Hospitals in running their business.Method - This research is a descriptive quantitative study conducted by survey method. The total of population are 40 Public Hospitals in Malang Raya and the sample obtained as respondents are 37 Public Hospitals spread across Malang District, Malang City and Batu City. The sample selection used probability sampling by sending a questionnaire to the entire population. Result - The results showed that the green accounting practices in Public Hospitals in Malang Raya based on financial activities, social activities and environmental activities had been implemented properly and consistently. Public Hospitals with higher types tended to be better and more consistent in applying green accounting than Public Hospitals with lower types (classes).Implication - With the awareness of Public Hospitals in Malang Raya to implement green accounting in the accountability of their business activities, it can have an impact, especially on environmental sustainability and the welfare of the community around the Public Hospital from the impact of the resulting waste.Originality - The concept of green accounting can also be implemented to Public Hospitals as a public entity. On this basis, of course, it is necessary to conduct research on the implementation of green accounting in Public Hospitals as a public entity so that in its operational activities it does not only consider the financial aspects to generate profits, but also considers environmental and social aspects. As a result, its business can have an impact especially on environmental sustainability and the welfare of the community around Public Hospitals from the impact of the waste produced.
A hybrid wavelet-Lyapunov exponent model for river water quality forecast
Authors: Jiang Jiping , Tang Sijie , Liu Rentao , Sivakumar Bellie , Wu Xiaoye , Pang Tianrui 
Published: May 2021

Abstract
The use of spectral theory and chaos theory on river water quality modeling is reported in a very limited way. This study proposes a wavelet-maximum Lyapunov exponent (WMLE) hybrid model for river water quality dynamics, combining spectral theory and chaos theory. The methodology involves the following major steps: (1) use of wavelet transformation to filter the noisy signal in the water quality time series; (2) reconstruction of phase space to embed the water quality time series and determine the trajectory of the underlying dynamics; and (3) identification of the presence/absence of chaos and prediction using the largest Lyapunov exponent value. Case studies on the Huaihe River in China and the Potomac River in the United States, as representatives of low-frequency and high-frequency forecast, show average relative errors on weekly dissolved oxygen (DO), chemical oxygen demand (COD), and ammonia nitrogen (NH3-N) data are 2.35%, 4.53%, and 18.85%, and on 15-minute based DO data are 1.185%. It also indicates that the hybrid model performs better to some extent when compared to the purely Lyapunov exponent model, ARMA model, and ANN model. This study is a proof that the combination of spectral theory and chaos theory is promising to describe and predict fluctuation of particular water quality indicators in rivers.
Gene Therapy as the New Frontier for Sickle Cell Disease
Authors: Garg Himanshu , Tatiossian Kristina J. , Peppel Karsten , Kato Gregory J. , Herzog Eva 
Published: May 2021

:
Sickle Cell Disease (SCD) is one of the most common monogenic disorders caused by a point mutation in the β-globin gene. This mutation results in polymerization of hemoglobin (Hb) under reduced oxygenation conditions, causing rigid sickle-shaped RBCs and hemolytic anemia. This clearly defined fundamental molecular mechanism makes SCD a prototypical target for precision therapy. Both the mutant β-globin protein and its down-stream pathophysiology are pharmacological targets of intensive research. SCD also is a disease well-suited for biological interventions like gene therapy. Recent advances in hem-atopoietic stem cell (HSC) transplantation and gene therapy platforms, like Lentiviral vec-tors and gene editing strategies, expand the potentially curative options for patients with SCD. This review discusses the recent advances in precision therapy for SCD and the pre-clinical and clinical advances in autologous HSC gene therapy for SCD.
Spectral, Crystalline, Thermal, Morphological Characterization and
Catalytic Performance of Ruthenium(III) Complexes of Natural
Biopolymer-Based Schiff Base Ligands
Authors: Vadivel T. , Dhamodaran M. , Kavitha S. 
Published: May 2021

Aims:
To achieve catalytic performance for the oxidation of alcohols using
Ruthenium(III) metal complexes as a catalyst.

Background:
Chitosan is a potential candidate, which enables the synthesis of transition metal
complexes from its corresponding bidentate ligands.

Objective:
The chemical modification was performed on a chitosan molecule with suitable
aldehydes.

Method:
The oxidation of alcohols was performed using ruthenium metal complexes as a catalyst
with pyridinium chlorochromate (PCC) as an oxidant and dichloromethane as a solvent. To a
solution of alcohol (2 mmol) and dichloromethane (25 mmol), pyridinium chlorochromate (3
mmol), and ruthenium(III) complexes (0.01 mmol) were added. The solution was stirred for 12 h at
room temperature. At the required time, the aldehyde/ketone was extracted with n-hexane. The nhexane
was then analyzed by GC.

Results:
The ruthenium(III) complexes derived from modified chitosan Schiff bidentate ligands have
resulted in good catalytic performance for the oxidation of alcohols under optimized conditions.

Conclusion:
The enhanced catalytic activities of ruthenium(III) complexes were due to the
presence of electron-donating groups in the Schiff base ligand.
Patient Rationales Against the Use of Patient-Accessible Electronic Health Records: Qualitative Study
Authors: Valeur Hanne Støre , Lie Anne Kveim , Moen Kåre 
Published: May 2021

Background
Patient-accessible electronic health records (PAEHRs) enable patients to access their health records through a secure connection over the internet. Although previous studies of patient experiences with this kind of service have shown that a majority of users are positive toward PAEHRs, little is known about why some patients occasionally or regularly choose not to use them. A better understanding of why patients may choose not to make use of digital health services such as PAEHRs is important for further development and implementation of services aimed at having patients participate in digital health services.

Objective
The objective of the study was to explore patients’ rationales for not embracing online access to health records.

Methods
Qualitative interviews were conducted with 40 patients in a department of internal medicine in a Norwegian hospital in 2018-2019. Interview transcripts were subjected to thematic content analysis. In this paper, we focus on the subject of nonuse of PAEHRs.

Results
We identified 8 different rationales that study participants had for not embracing PAEHRs. When patients reflected on why they might not use PAEHRs, they variously explained that they found PAEHRs unnecessary (they did not feel they were useful), impersonal (they preferred oral dialogue with their doctor or nurse over written information), incomprehensible (the records contained medical terminology and explanations that were hard to understand), misery oriented (the records solely focused on disease), fear provoking (reading the records could cause unwanted emotional reactions), energy demanding (making sense of the records added to the work of being a patient), cumbersome (especially among patients who felt they did not have the necessary digital competence), and impoverishing (they were skeptical about the digital transformation of individual and social life).

Conclusions
It is often assumed that the barriers to PAEHR use are mostly practical (such as lack of hardware and access to the internet). In this study, we showed that patients may have many other valid reasons for not wanting to adopt this kind of service. The results can help guide how PAEHRs and other digital health services are promoted and presented to patients, and they may suggest that the goal of a given new digital health service should not necessarily be full uptake by all patients. Rather, one should recognize that different patients might prefer and benefit from different kinds of “analog” and digital health services.
Penerapan Sistem Data Cleansing untuk Mencegah dan Menghilangkan Duplikasi Rekam Medis
Authors: Rokhman Nur , Ningtyas Annisa Maulida , Salim Marko Ferdian , Santoso Dian Budi 
Published: May 2021

Health Information System is a system that integrates the collection, processing, reporting of data, and use of information needed to increase the effectiveness and efficiency of health services through better management at all levels of health services. Kulon Progo Health Office is one of the Health Services that has utilized the Health Information System in organizing its health transactions. However, the implementation of the Health Information System still has shortcomings, namely that it was found that a patient has many medical record numbers or often referred to as duplicated medical record data. Community service activities are carried out through the use of appropriate technology at the Kulon Progo Health Office. This activity aims to implement data cleansing techniques using the "RESIK" framework to help prevent and detect duplication of medical records and provide training to medical recorders in cleaning data. The training was attended by 105 participants, each of whom was a representative of the Puskesmas staff in the Kulon Progo Health Office area. The “RESIK” framework was then piloted at Puskesmas Sentolo 2 as the location for the implementation of the system. From this activity, duplicate medical record data can be found at Puskesmas Sentolo 2, and then cleaning is carried out. Kulon Progo Health Office is advised to implement data cleansing using the "RESIK" framework at all Puskesmas in the Kulon Progo area.
Stand structure-dependent mass-ratio and complementarity effects simultaneously drive aboveground biomass in temperate Quercus forests
Authors: Gao Wen-Qiang , lei xiangdong , Gao Dong-Li , Li Yu-Tang 
Published: May 2021

Aim: Forests play a key role in regulating the global carbon
cycle, a substantial portion of which is stored in aboveground biomass
(AGB). It is well-understood that biodiversity can increase the
biomass through complementarity and mass-ratio effects, and the
contribution of environmental factors and stand structure attributes to
AGB was also observed. However, the relative influence of these factors
in determining the AGB of Quercus forests remains poorly
understood. Location: Temperate Quercus forests in
northeastern China. Methods: Using a large dataset retrieved
from 523 permanent forest inventory plots across Northeast China, we
examined the effects of integrated multiple tree species diversity
components (i.e., species richness, functional and phylogenetic
diversity), functional traits composition, environmental factors
(climate and soil), stand age, and structure attributes (stand density,
tree size diversity) on AGB based on structural equation models.
Results: We found that species richness and phylogenetic
diversity both were not correlated with AGB. However, functional
diversity positively affected AGB via an indirect effect in line with
the complementarity effect. Moreover, the community-weighted mean of
specific leaf area and height increased AGB directly and indirectly,
respectively; demonstrating the mass-ratio effect. Furthermore, stand
age, density, and tree size diversity were more important modulators of
AGB than biodiversity. Main conclusions: Our study highlights
that biodiversity-AGB interaction is dependent on the regulation of
stand structure that can be even more important for maintaining high
biomass than biodiversity in temperate Quercus forests.
Group Judgment and Decision Making in Auditing: Research in the Time of COVID-19 and Beyond
Authors: Bauer Tim D. , Humphreys Kerry A. , Trotman Ken T. 
Published: May 2021

SUMMARY
The COVID-19 pandemic has fundamentally changed how auditors work and interact with team members and others in the financial reporting process. In particular, there has been a move away from face-to-face interactions to the use of virtual teams, with strong indications many of these changes will remain post-pandemic. We examine the impacts of the pandemic on group judgment and decision making (JDM) research in auditing by reviewing research on auditor interactions with respect to the review process (including coaching), fraud brainstorming, consultations within audit firms, and parties outside the audit firm such as client management and the audit committee. Through the pandemic lens and for each auditor interaction, we consider new research questions for audit JDM researchers to investigate and new ways of addressing existing research questions given these fundamental changes. We also identify potential impacts on research methods used to address these questions during the pandemic and beyond.
GenUI: Interactive and Extensible Open Source Software Platform for De Novo Molecular Generation
Authors: Šícho Martin , Liu Xuhan , Svozil Daniel , van Westen Gerard 
Published: May 2021

This manuscript describes the development and architecture of the GenUI software platform for integration of molecular generators. The source code for the components of the platform is available in the following repositories:https://github.com/martin-sicho/genuihttps://github.com/martin-sicho/genui-guihttps://github.com/martin-sicho/genui-docker
Los Escalones del Abuelo
Authors: De la Torre Santiago 
Published: May 2021

“Los escalones del Abuelo” es la serie fotográfica expuesta en el Museo Archivo de Arquitectura del Ecuador desde el 29 de febrero hasta el 5 de agosto del 2020. Tras varios años documentando la obra arquitectónica de Oswaldo de la Torre (1926-2012), mi abuelo paterno, propongo este ensayo que juega entre la imagen fotográfica y la imagen arquitectónica caminando en la cuerda floja entre sus pares dialécticos: luz – oscuridad, instante – eternidad, recuerdo – olvido, realidad – ficción, presencia – ausencia, entre otros.
Este ensayo propone un recorrido histórico y reflexivo acerca de la herencia arquitectónica cultural, la relación entre la arquitectura la fotografía y la luz y el papel de la fotografía para preservar la memoria.
Risk factors for acquisition of colistin-resistant Klebsiella pneumoniae and expansion of a colistin-resistant ST307 epidemic clone in hospitals in Marseille, France, 2014 to 2017
Authors: Baron Sophie Alexandra , Cassir Nadim , Hamel Mouna , Hadjadj Linda , Saidani Nadia , Dubourg Gregory , Rolain Jean-Marc 
Published: May 2021

Background
France is a low prevalence country for colistin resistance. Molecular and epidemiological events contributing to the emergence of resistance to colistin, one of the 'last-resort' antibiotics to treat multidrug-resistant Gram-negative infections, are important to investigate.

Aim
This retrospective (2014 to 2017) observational study aimed to identify risk factors associated with acquisition of colistin-resistant Klebsiella pneumoniae (CRKP) in hospitals in Marseille, France, and to molecularly characterise clinical isolates.

Methods
To identify risk factors for CRKP, a matched-case–control (1:2) study was performed in two groups of patients with CRKP or colistin-susceptible K. pneumoniae respectively. Whole-genome-sequences (WGS) of CRKP were compared with 6,412 K. pneumoniae genomes available at the National Center for Biotechnology Information (NCBI).

Results
Multivariate analysis identified male sex and contact with a patient carrying a CRKP as significant independent factors (p < 0.05) for CRKP acquisition, but not colistin administration. WGS of nine of 14 CRKP clinical isolates belonged to the same sequence type (ST)307. These isolates were from patients who had been hospitalised in the same wards, suggesting an outbreak. Comparison of the corresponding strains’ WGS to K. pneumoniae genomes in NCBI revealed that in chromosomal genes likely playing a role in colistin resistance, a subset of five specific mutations were significantly associated with ST307 (p < 0.001).

Conclusion
A ST307 CRKP clone was identified in this study, with specific chromosomal mutations in genes potentially implicated in colistin resistance. ST307 might have a propensity to be or become resistant to colistin, however confirming this requires further investigations.