bluuebunny/crossref_metadata_2025_split huggingface dataset:
IMPLEMENTASI KEBIJAKAN PAJAK REKLAME DAN KONTRIBUSINYA TERHADAP PENDAPATAN ASLI DAERAH KABUPATEN DONGGALA
Authors: Qosim Nanang 
Published: February 2021

Populasi dalam penelitian ini adalah seluruh pegawai pada Kantor Dinas Pendapatan Dan Pengelolaan Keuangan dan Asset Daerah Kabupaten Donggala yang berjumlah 100 orang dan masyarakat yang menjadi wajib pajak reklame. Penelitian ini mengambil seluruh populasi yaitu sampling jenuh (sensus).
Hasil penelitian menunjukkan bahwa implementasi kebijakan Pajak Reklame terhadap peningkatan Pendapatan Asli Daerah pada Dinas Pendapatan, Pengelolaan Keuangan dan Asset Daerah Kabupaten Donggala yang terdiri dari empat indikator yaitu komunikasi (communication), Sumber-sumber (resources), dampak (dispositions) dan Birokrasi (bureaucratic). Dari keempat indikator tersebut masih ada sub indikator yang masih perlu ditingkatkan yaitu sub indikator sarana dan prasarana, pelaksana kebijakan, perilaku pembuat kebijakan, dan kesesuaian pelayanan, namun secara akumulatif responden memberikan tanggapan efektif atau baik. Realisasi pajak reklame dari tahun ke tahun menunjukkan peningkatan dimana pada tahun 2012 dan 2013 relisasi pajak reklame dapat melampai target walaupu n persentasi pencapaiannya menurun pada tahun 2012 sebesar 126,7% menjadi 104% pada tahun 2013. Kontribusi pajak reklame terhadap Pendapatan Asli Daerah Kabupaten Donggala masih sangat kurang dengan nilai kontribusi pada tahun 2011 hingga 2013 hanya berkisar rata-rata 0.3% dari PAD. Ini menunjukkan sektor usaha produktif rakyat tidak berkembang sehingga kegiatan promosi dengan pemasangan reklame rendah. Faktor yang mempengaruhi terhadap realisasi pajak reklame Pendapatan Asli Daerah Pada Dinas Pendapatan Daerah Kabupaten Donggala dapat dijelaskan yaitu : Faktor penghambat dan pendukung realisasi tahun sebelumnya, Pencairah Tagihan Tahun Sebelumnya, Data Potensi dan Estimasi, Penyesuain tarif dan penyempurnaan system pungutan masih perlu ditingkatkan dan menjaadi perhatian bagi implementator. Sedangkan faktor Keadaan Sosial-ekonomi dan kesadaran wajib pajak dan Kebijakan ekonomi dan moneter harus menjadi perhatian khusus Pemerintah Daerah Kabupaten Donggala karena besar kecilnya penerimaan daerah tergantung keadaan ekonomi dan sosial masyarakat maka perlu ada kebijakan – kebijakan ekonomi yang dapat meningkatkan taraf ekonomi dan sosial masyarakat Kabupaten Donggala.

Kata Kunci: Implementasi Pajak Reklame, Kebijakan Pajak Reklame dan Pendapatran Asli Daerah
PENGARUH BUDAYA ORGANISASI KOMITMEN DAN KOMPENSASI TERHADAP KINERJA PEGAWAI PADA UNIVERSITAS ALKHAIRAAT PALU
Authors: Kaiyeli Nasrula 
Published: February 2021

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh budaya organisasi, komitmen dan kompensasi terhadap kinerja pegawai Universitas Alkhairaat Palu; pengaruh budaya organisasi terhadap kinerja pegawai Universitas Alkhairaat Palu, pengaruh komitmen terhadap kinerja pegawai Universitas Alkhairaat Palu, pengaruh kompensasi terhadap kinerja pegawai Universitas Alkhairaat Palu. Sampel dalam penelitian ini adalah yaitu 86 pegawai. Teknik penarikan sampel menggunakan metode sensus dengan tujuan agar dapat memperoleh informasi yang lebih lengkap tentang kondisi sebenarnya. Alat analisis yang digunakan adalah analisis regresi linear berganda. Hasil penelitian menunjukkan bahwa: hasil perhitungan diperoleh Fhitung = 28.014 pada taraf nyata ά = 0,05 atau Sig F< 0,05. nilai signifikansi F = 0,000. Dengan demikian dapat dinyatakan bahwa secara simultan variabel budaya organisasi, komitmen dan kompensasi berpengaruh positif dan signifikan terhadap kinerja ; variabel budaya organisasi berpengaruh signifikan terhadap kinerja dengan nilai sig 0.002; komitmen tidak berpengaruh signifikan terhadap kinerja dengan nilai sig 0.530.; kompensasi berpengaruh signifikan terhadap kinerja dengan nilai sig 0.242.

Kata Kunci: Budaya Organisasi, Komitmen, Kompensasi, Kinerja.
Hawthorn berry (crataegus songarica) causes endothelium-dependent relaxation of the porcine coronary artery: Role of Estrogen receptors
Authors: Younis Waqas , Alamgeer  , Schini-Kerth Valerie B. , Farooq Muhammad Akmal , Althobaiti Musaad , Roberts Richard E. 
Published: February 2021

BACKGROUND: Fruits of Crataegus songarica are commonly used for the treatment of vascular insufficiency and heart problems. OBJECTIVE: Our aim was to determine the effect of C. songarica on vascular tone and to determine the mechanisms underlying the vasorelaxant properties. METHODS: Extracts of C. songarica were tested for vasodilator activity of porcine coronary artery after pre-contraction with the thromboxane mimetic U46619 in the presence or absence of inhibitors of intracellular signaling cascades. Reactive oxygen species were assessed by dihydroethidine staining and the level of eNOS and AKT phosphorylation was measured by immunohistochemical staining. RESULTS: Extracts of C. songarica berries produced endothelium dependent vasorelaxation, with most significant effect induced by aqueous fraction (AS-CS). This vasorelaxant effect of AS-CS was reduced by inhibition of nitric oxide pathways and inhibition of potassium channels. Inhibition of phosphatidylinositol 3- kinase and Src tyrosine kinase, as well as scavenging of reactive oxygen species, produced an attenuation of the relaxation response. Estrogen receptor antagonists (tamoxifen and ICI 182,782) reduced the AS-CS mediated vasorelaxation. AS-CS also stimulated the endothelial formation of ROS and phosphorylation of Akt and eNOS. CONCLUSION: The data indicated that C. songarica produces an endothelium-dependent vasorelaxation, which is partly dependent upon estrogen receptors, and sensitive to inhibition of ROS/Src/PI3K/NO pathways.
Komparasi Penetapan Tarif INA_CBGs dan Tarif Rumah Sakit dengan Diagnosa Dengue Hemorrhagic Fever (DHF) Peserta Jaminan Kesehatan Nasional, Studi Empiris di Rumah Sakit Medika Dramaga - Bogor
Authors: Indupurnahayu Indupurnahayu , Aminda Renea Shinta , Rahayu Renny 
Published: February 2021

<span>Dalam pelaksanaanya, walaupun JKN (Jaminan Kesehatan Nasional) melalui Badan Penyelenggara Jaminan Sosial Kesehatan (BPJS Kesehatan) sudah dilakukan kurang lebih 5-6 tahun lalu masih sering dijumpai celah perbedaan tarif antara Indonesia Case Based Group (INA-BCGs) dengan penetapan tarif oleh Rumah Sakit yang dirujuk pasien. Berdasarkan data dan kondisi empiris tersebut maka penelitian ini dilakukan untuk dapat menjawab perhitungan penetapan tarif INA_CBGs pada pasien rawat inap dan rawat jalan untuk kasus penyakit yang diakibatkan oleh Nyamuk Demam Berdarah (DBD) atau yang leBih dikenal dengan nama Dengue Hemorrhagic Fever (DHF). Penelitian dilakukan untuk mengkonfirmasi besaran dasar penetapan tarif INA_CBGs, dan menghitung serta menganalisis formulasi dalam penyelesaian selisih perhitungan Tarif INA_CBgs dan tarif Rumah Sakit yang dirujuk pasien. Hasil penelitian menunjukkan adanya perbedaan tariff pada pasien rawat inap. Adapun formulasi praktis jangka peendek adalah subsidi silang dan model alternatif perhitungan perbedaan tarif yang ideal bagi rumah sakit dalam mengatasi selisih negative adalah dengan mengakomodasi selisih tarif melalui konfirmasi 2 arah BPJS kesehatan dan Administator Rumah sakit.</span>
An Applied Study for the Restoration and Conservation of a Museum-Stored Colored Stone Coffin lid from the Late Period
Authors: Shaimaa Sayed Mohamed El-Sayed  
Published: February 2021

The colored stone coffin lids are exposed to many different deterioration factors, whether in the burial or exposure environment. In the burial environment, these colored coffin lids are subjected to the pressure of soil sediments, which leads to their being crushed into parts, especially since the case study is made of limestone. In the soil, caused by the presence of ground water, which leads to the crystallization of salts and the growth of microorganisms. Also, false excavation of these colored stone coffins lids and their transfer from equilibrium in the burial environment to the exposure environment leads to exposing to other pressures and may lead to irreversible damage and loss of color, as the temperature difference in the exposure environment and burial environment will lead to fissures and cracks as well. Crystallization of salts in the case of high temperature, as well as the difference in relative humidity levels, will lead to the dissolution of the color-bonding material and the dissolution of the air pollution gases, which leads to the formation of acids that interact with the material of these stone coffins lids to form water-soluble compounds, which leads in the end to the loss and deterioration of them. The selected object of study is a colored stone coffin lid no. 1939, broken into several parts of limestone (about 13 parts), dated to the Late Period and saved in Atifyah museum store – Ministry of Tourism and Antiquities- Giza – Egypt, samples were taken from limestone, red and black pigments and examined by optical microscope, polarizing microscope and Scanning Electron Microscope (SEM) also analyzed by X-Ray Diffraction (XRD). The restoration processes are summarized in cleaning, consolidation, assembling and loss- compensation for the selected colored stone coffin lid.
Growth performance of jute (Corchorus capsularies L.) as influenced by different organic manures
Authors: Qulsum U , Meem FF , Promi RS , Zaman JR , Ara MF , Rahman MK 
Published: February 2021

A pot experiment was carried out in 2019 in the net house of the Department of Soil, Water and Environment, University of Dhaka, to evaluate the growth and yield of Jute plants (Corchorus capsularies L.) by applying different types of organic manures. Eight different types of organic manures viz. ACI, BGF-1, Mazim, Vermicompost, Shufola, GTS, Green and Poultry manures were collected from the local market. The experiment was set up following a completely randomized design (CRD) with nine treatments and three replications consisting of twenty-seven pots. Significant variation was observed in different growth and yield contributing characters. The highest plant height (19.83cm) in poultry manure, leaf number (8.33/plant) was observed in Green manure, leaf area (21.93 cm2 / plant) in Poultry manure, fresh weight (3.18g) and dry weight (2.25 g) were found in Poultry manure, stem girth (1.67 cm/plant) in Vermicompost, branch number (8.6/plant) in Green manure. The highest nutrient uptake by plants (kg/ha) occurred in Poultry manure. The overall best growth was observed in Poultry manure.
J. Biodivers. Conserv. Bioresour. Manag. 2020, 6(1): 17-24
Role of honey bee on mustard (Brassica spp.) yield
Authors: Hossain MS , Paul JK , Rahman MM , Fazlullah MU , Sarkar S 
Published: February 2021

The study was conducted in the field at Nagarpur, Tangail, Bangladesh, from November 2016 to February 2017 to find out the role of honey bees on mustard yield. Honey bee (Apis mellifera) was the main insect pollinator during mustard flowering season. Mustard seeds of variety Tori-7 were selected for this experiment. Three different treatments were used, viz. control, netting with honey bees and netting without honey bees. Honey bees helped mustard pollination, but decreased the flowering period (6 days) of the mustard plant. Honey bees assisted the pollination of mustard and increased the number of pod per plant (14%) as well as the number of seeds per pod (11%). Honey bees enhanced the pollination of mustard plant, and netting with honey bees increased the mean seed yield (15%) per plant of mustard, however, decreased the period of flowering stage of mustard. Mustard yield was considerably higher in honey bee foraging plots.
J. Biodivers. Conserv. Bioresour. Manag. 2020, 6(1): 25-30
Imipenem Resistance Gram-Negative Bacilli Isolated from Patients of a Tertiary Care Hospital in Dhaka, Bangladesh
Authors: Mostofa Hasbi Ara , Shamsuzzaman SM , Hasan Md Maniul , Shormin Moonmoon , Das Bithi , Habiba Umme , Rahman Md Mustafizur , Akhter Shakila 
Published: February 2021

Introduction: The emergence of antibiotics resistance bacteria is a persistent global problem affecting public health. The occurrence and widespread resistance to Imipenem among hospital bacterial isolates can constitute a significant threat to chemotherapy.
Objectives: This cross-sectional study aimed to investigate the imipenem resistant pattern among gram-negative bacilli isolated from different samples in Dhaka medical college hospital.
Methods: A total of 300 samples (wound swab, urine, endotracheal aspirate, blood, and sputum) were collected from July 2015 to June 2016. Two hundred four gram-negative bacilli were isolated and tested for resistance to imipenem by the disc diffusion method.
Results: Among 204-gram negative bacilli, 39.21% imipenem resistance was detected by the Disc Diffusion method. 14.7% imipenem resistance gram-negative bacilli were from wound swab. 83.33% of Acinetobacter baumannii were Imipenem resistant.
Conclusions: Imipenem resistance is widespread among gram-negative bacilli isolated from human infections. Imipenem resistance (39.21%) found in the study is quite worrisome.
J Shaheed Suhrawardy Med Coll, December 2020, Vol.12(1); 3-5
Paracoccidioides brasiliensis Releases a DNase-Like Protein That Degrades NETs and Allows for Fungal Escape
Authors: Zonta Yohan Ricci , Dezen Ana Laura Ortega , Della Coletta Amanda Manoel , Yu Kaio Shu Tsyr , Carvalho Larissa , Santos Leandro Alves dos , Deprá Igor de Carvalho , Kratofil Rachel M. , Willson Michelle Elizabeth , Zbytnuik Lori , Kubes Paul , Ximenes Valdecir Farias , Dias-Melicio Luciane Alarcão 
Published: February 2021

Paracoccidioidomycosis is a systemic fungal disease, considered endemic in Latin America. Its etiological agents, fungi of theParacoccidioidescomplex, have restricted geographic habitat, conidia as infecting form, and thermo-dimorphic characteristics. Polymorphonuclear neutrophils (PMNs) are responsible for an important defense response against fungus, releasing Neutrophil Extracellular Traps (NETs), which can wrap and destroy the yeasts. However, it has been described that some pathogens are able to evade from these DNA structures by releasing DNase as an escape mechanism. As different NETs patterns have been identified in PMNs cultures challenged with different isolates ofParacoccidioides brasiliensis, the general objective of this study was to identify if different patterns of NETs released by human PMNs challenged with Pb18 (virulent) and Pb265 (avirulent) isolates would be correlated with fungal ability to produce a DNase-like protein. To this end, PMNs from healthy subjects were isolated and challengedin vitrowith both fungal isolates. The production, release, and conformation of NETs in response to the fungi were evaluated by Confocal Microscopy, Scanning Microscopy, and NETs Quantification. The identification of fungal DNase production was assessed by DNase TEST Agar, and the relative gene expression for hypothetical proteins was investigated by RT-qPCR, whose genes had been identified in the fungal genome in the GenBank (PADG_11161 and PADG_08285). It was possible to verify the NETs release by PMNs, showing different NETs formation when in contact with different isolates of the fungus. The Pb18 isolate induced the release of looser, larger, and more looking like degraded NETs compared to the Pb265 isolate, which induced the release of denser and more compact NETs. DNase TEST Agar identified the production of a DNase-like protein, showing that only Pb18 showed the capacity to degrade DNA in these plates. Besides that, we were able to identify that both PADG_08528 and PADG_11161 genes were more expressed during interaction with neutrophil by the virulent isolate, being PADG_08528 highly expressed in these cultures, demonstrating that this gene could have a greater contribution to the production of the protein. Thus, we identified that the virulent isolate is inducing more scattered and loose NETs, probably by releasing a DNase-like protein. This factor could be an important escape mechanism used by the fungus to escape the NETs action.
Extraction of Coronary Atherosclerotic Plaques From Computed Tomography Imaging: A Review of Recent Methods
Authors: Liu Haipeng , Wingert Aleksandra , Wang Jian'an , Zhang Jucheng , Wang Xinhong , Sun Jianzhong , Chen Fei , Khalid Syed Ghufran , Jiang Jun , Zheng Dingchang 
Published: February 2021

Background: Atherosclerotic plaques are the major cause of coronary artery disease (CAD). Currently, computed tomography (CT) is the most commonly applied imaging technique in the diagnosis of CAD. However, the accurate extraction of coronary plaque geometry from CT images is still challenging.Summary of Review: In this review, we focused on the methods in recent studies on the CT-based coronary plaque extraction. According to the dimension of plaque extraction method, the studies were categorized into two-dimensional (2D) and three-dimensional (3D) ones. In each category, the studies were analyzed in terms of data, methods, and evaluation. We summarized the merits and limitations of current methods, as well as the future directions for efficient and accurate extraction of coronary plaques using CT imaging.Conclusion: The methodological innovations are important for more accurate CT-based assessment of coronary plaques in clinical applications. The large-scale studies, de-blooming algorithms, more standardized datasets, and more detailed classification of non-calcified plaques could improve the accuracy of coronary plaque extraction from CT images. More multidimensional geometric parameters can be derived from the 3D geometry of coronary plaques. Additionally, machine learning and automatic 3D reconstruction could improve the efficiency of coronary plaque extraction in future studies.
Access to and Quality of Healthcare for Pregnant and Postpartum Women During the COVID-19 Pandemic
Authors: Brislane Áine , Larkin Fionnuala , Jones Helen , Davenport Margie H. 
Published: February 2021

Introduction: During the COVID-19 pandemic, obstetric care has adopted new precautions to ensure services can be maintained for pregnant women. The aim of this study was to describe access to and quality of obstetric care for pregnant and postpartum women during the COVID-19 pandemic and to identify factors that predict quality of care at this time.Methods: Between May 3 and June 28, 2020, we recruited women who were pregnant or within the first 6 months after delivery to participate in an online survey. This included questions on access to obstetric healthcare (type and place of health care provider, changes to obstetric appointments/services, appointment preferences) and the Quality of Prenatal Care Questionnaire (QPCQ).Results: Of the 917 eligible women, 612 (67%) were pregnant and 305 (33%) were in the first 6 months after delivery. Sixty-two percent (n = 571) reported that COVID-19 had affected their healthcare; appointments were rearranged, canceled or occurred via virtual means for 29% (n = 166), 29% (n = 167), and 31% (n = 175) of women, respectively. The majority preferred to physically attend appointments (74%; n = 676) and perceived the accompaniment of birth partners as important (77%; n = 471). Sixty-two percent (n = 380) were permitted a birth partner at delivery, 18% (n = 111) were unsure of the rules while 4% (n = 26) were not permitted accompaniment. During pregnancy, QPCQ was negatively associated with disruption to obstetric services including exclusion or uncertainty regarding birth partner permissions [F(7, 433) = 11.5, p &lt; 0.001, R2 = 0.16] while QPCQ was negatively associated with inadequate breastfeeding support postpartum [F(1, 147) = 12.05, p = 0.001, R2 = 0.08].Conclusion: Pregnant and postpartum have experienced disruption in their access to obstetric healthcare. Perceived quality of obstetric care was negatively influenced by cancellation of appointment(s), suspension of services and exclusion of birth partners at delivery. During this time, continuity of care can be fulfilled via virtual and/or phone appointments and women should receive clear guidance on changes to services including birth partner permissions to attend delivery.
CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model
Authors: Sala Ester , Vived Celia , Luna Júlia , Saavedra-Ávila Noemí Alejandra , Sengupta Upasana , Castaño A. Raúl , Villar-Pazos Sabrina , Haba Laura , Verdaguer Joan , Ropero Ana B. , Stratmann Thomas , Pizarro Javier , Vázquez-Carrera Manuel , Nadal Angel , Lahti Jill M. , Mora Conchi 
Published: February 2021

BackgroundPancreatic islets are exposed to strong pro-apoptotic stimuli: inflammation and hyperglycemia, during the progression of the autoimmune diabetes (T1D). We found that the Cdk11(Cyclin Dependent Kinase 11) is downregulated by inflammation in the T1D prone NOD (non-obese diabetic) mouse model. The aim of this study is to determine the role of CDK11 in the pathogenesis of T1D and to assess the hierarchical relationship between CDK11 and Cyclin D3 in beta cell viability, since Cyclin D3, a natural ligand for CDK11, promotes beta cell viability and fitness in front of glucose.MethodsWe studied T1D pathogenesis in NOD mice hemideficient for CDK11 (N-HTZ), and, in N-HTZ deficient for Cyclin D3 (K11HTZ-D3KO), in comparison to their respective controls (N-WT and K11WT-D3KO). Moreover, we exposed pancreatic islets to either pro-inflammatory cytokines in the presence of increasing glucose concentrations, or Thapsigargin, an Endoplasmic Reticulum (ER)-stress inducing agent, and assessed apoptotic events. The expression of key ER-stress markers (Chop, Atf4 and Bip) was also determined.ResultsN-HTZ mice were significantly protected against T1D, and NS-HTZ pancreatic islets exhibited an impaired sensitivity to cytokine-induced apoptosis, regardless of glucose concentration. However, thapsigargin-induced apoptosis was not altered. Furthermore, CDK11 hemideficiency did not attenuate the exacerbation of T1D caused by Cyclin D3 deficiency.ConclusionsThis study is the first to report that CDK11 is repressed in T1D as a protection mechanism against inflammation-induced apoptosis and suggests that CDK11 lies upstream Cyclin D3 signaling. We unveil the CDK11/Cyclin D3 tandem as a new potential intervention target in T1D.