bluuebunny/crossref_metadata_2025_split huggingface dataset:
MYBL2 Gene Polymorphism Is Associated With Acute Lymphoblastic Leukemia Susceptibility in Children
Authors: Guo Haixia , Li Na , Sun Yaping , Wu Cuiling , Deng Huixia , Xu Ling , Yang Xu 
Published: September 2021

PurposeAlthough MYBL2 had been validated to participate in multiple cancers including leukemia, the role of MYBL2 polymorphisms in acute lymphoblastic leukemia (ALL) was still not clear. In this study, we aimed to evaluate the association between MYBL2 single nucleotide polymorphisms (SNPs) and ALL risk in children.MethodsA total of 687 pediatric ALL cases and 971 cancer-free controls from two hospitals in South China were recruited. A case-control study by genotyping three SNPs in the MYBL2 gene (rs285162 C&gt;T, rs285207 A&gt;C, and rs2070235 A&gt;G) was conducted. The associations were assessed by odds ratios (ORs) with corresponding 95% confidence intervals (CIs). Subgroup and stratification analyses were conducted to explore the association of rs285207 with ALL risk in terms of age, sex, immunophenotype, risk level, and other clinical characteristics. The false-positive report probability (FPRP) analysis was performed to verify each significant finding. Functional analysis in silico was used to evaluate the probability that rs285207 might influence the regulation of MYBL2.ResultsOur study demonstrated that rs285207 was related to a decreased ALL risk (adjusted OR = 0.78; 95% CI = 0.63-0.97, P = 0.022) in the dominant model. The associations of rs285207 with ALL risk appeared stronger in patients with pre B ALL (adjusted OR=0.56; 95% CI=0.38-0.84, P=0.004), with normal diploid (adjusted OR=0.73; 95% CI=0.57-0.95, P=0.017), with low risk (adjusted OR=0.68; 95% CI=0.49-0.94, P=0.021), with lower WBC (adjusted OR=0.62; 95% CI=0.43-0.87, P=0.007) or lower platelet level (adjusted OR=0.76; 95% CI=0.59-0.96, P=0.023). With FPRP analysis, the significant association between the rs285207 polymorphism and decreased ALL risk was still noteworthy (FPRP=0.128). Functional analysis showed that IKZF1 bound to DNA motif overlapping rs285207 and had a higher preference for the risk allele A. As for rs285162 C&gt;T and rs2070235 A&gt;G, no significant was found between them and ALL risk.ConclusionIn this study, we revealed that rs285207 polymorphism decreased the ALL risk in children, and rs285207 might alter the binding to IKZF1, which indicated that the MYBL2 gene polymorphism might be a potential biomarker of childhood ALL.
Comparison of Complex k-Space Data and Magnitude-Only for Training of Deep Learning–Based Artifact Suppression for Real-Time Cine MRI
Authors: Haji-Valizadeh Hassan , Guo Rui , Kucukseymen Selcuk , Tuyen Yankama , Rodriguez Jennifer , Paskavitz Amanda , Pierce Patrick , Goddu Beth , Ngo Long H. , Nezafat Reza 
Published: September 2021

Propose: The purpose of this study was to compare the performance of deep learning networks trained with complex-valued and magnitude images in suppressing the aliasing artifact for highly accelerated real-time cine MRI.Methods: Two 3D U-net models (Complex-Valued-Net and Magnitude-Net) were implemented to suppress aliasing artifacts in real-time cine images. ECG-segmented cine images (n = 503) generated from both complex k-space data and magnitude-only DICOM were used to synthetize radial real-time cine MRI. Complex-Valued-Net and Magnitude-Net were trained with fully sampled and synthetized radial real-time cine pairs generated from highly undersampled (12-fold) complex k-space and DICOM images, respectively. Real-time cine was prospectively acquired in 29 patients with 12-fold accelerated free-breathing tiny golden-angle radial sequence and reconstructed with both Complex-Valued-Net and Magnitude-Net. Cardiac function, left-ventricular (LV) structure, and subjective image quality [1(non-diagnostic)-5(excellent)] were calculated from Complex-Valued-Net– and Magnitude-Net–reconstructed real-time cine datasets and compared to those of ECG-segmented cine (reference).Results: Free-breathing real-time cine reconstructed by both networks had high correlation (all R2 &gt; 0.7) and good agreement (all p &gt; 0.05) with standard clinical ECG-segmented cine with respect to LV function and structural parameters. Real-time cine reconstructed by Complex-Valued-Net had superior image quality compared to images from Magnitude-Net in terms of myocardial edge sharpness (Complex-Valued-Net = 3.5 ± 0.5; Magnitude-Net = 2.6 ± 0.5), temporal fidelity (Complex-Valued-Net = 3.1 ± 0.4; Magnitude-Net = 2.1 ± 0.4), and artifact suppression (Complex-Valued-Net = 3.1 ± 0.5; Magnitude-Net = 2.0 ± 0.0), which were all inferior to those of ECG-segmented cine (4.1 ± 1.4, 3.9 ± 1.0, and 4.0 ± 1.1).Conclusion: Compared to Magnitude-Net, Complex-Valued-Net produced improved subjective image quality for reconstructed real-time cine images and did not show any difference in quantitative measures of LV function and structure.
Sex Differences in Psychological Status and Fatigue of Frontline Staff After the COVID-19 Outbreak in China: A Cross-Sectional Study
Authors: Teng Ziwei , Su Yuhan , Chen Jindong , Wu Renrong , Tang Hui , Wu Haishan , Liu Xuming , Ling Heqiao , Yuan Hui , Huang Jing 
Published: September 2021

Background: The coronavirus disease 2019 (COVID-19) is spreading globally, and it is significant to pay attention to the mental health of frontline staff in this pandemic. This study is aimed to explore the sex difference among the frontline staff in demographics, characteristics of mental state, and the potential relationship between them.Method: A total of 2,614 Chinese frontline staff were recruited. The Self-Rating Anxiety Scale (SAS) and the Patient Health Questionnaire-9 (PHQ-9) were used for assessing the mental status of frontline staff, and the Fatigue Self-Assessment Scale (FSAS) was used for detecting fatigue.Result: The prevalence rate of anxiety for female frontline staff is higher than that of male (P = 0.003), and the prevalence rate of depression is similar between them (P = 0.091). After comparing the risk factors of unhealthy mental state between different sexes, it is found that family income below 100,000 [depression: odds ratio (OR) 1.37; 95% CI, 1.08–1.73; anxiety: OR 1.99; 95% CI, 1.44–2.75], unsupported of family (depression: OR 10.94; 95% CI, 1.39–85.79; anxiety: OR 11.92; 95% CI, 3.80–37.36), and marriage (depression: OR 1.67; 95% CI, 1.15–2.43) are risk factors for male, and total fatigue (depression: OR 2.96; 95% CI, 1.46–6.02) is risk factor for female.Conclusions: This study found that depression and anxiety are widespread among the frontline staff of COVID-19, and anxiety showed a higher prevalence rate among female frontline staff. From the sex difference in risk factors, the focus of psychological interventions may differ between genders. Men with low family income, unsupported by family or marriage, and women with a high score of total fatigue required particular attention to their psychological status.
Leadership Styles and Organizational Citizenship Behavior for the Environment: The Mediating Role of Self-Efficacy and Psychological Ownership
Authors: Ullah Irfan , Wisetsri Worakamol , Wu Hao , Shah Syed Mehmood Ali , Abbas Ali , Manzoor Shahid 
Published: September 2021

Graphical AbstractGraphical abstract shows the visual representation of direct and indirect relationships.
Evaluation of Version 3 Total and Tropospheric Ozone Columns From Earth Polychromatic Imaging Camera on Deep Space Climate Observatory for Studying Regional Scale Ozone Variations
Authors: Kramarova Natalya A. , Ziemke Jerald R. , Huang Liang-Kang , Herman Jay R. , Wargan Krzysztof , Seftor Colin J. , Labow Gordon J. , Oman Luke D. 
Published: September 2021

Discrete wavelength radiance measurements from the Deep Space Climate Observatory (DSCOVR) Earth Polychromatic Imaging Camera (EPIC) allows derivation of global synoptic maps of total and tropospheric ozone columns every hour during Northern Hemisphere (NH) Summer or 2 hours during Northern Hemisphere winter. In this study, we present version 3 retrieval of Earth Polychromatic Imaging Camera ozone that covers the period from June 2015 to the present with improved geolocation, calibration, and algorithmic updates. The accuracy of total and tropospheric ozone measurements from EPIC have been evaluated using correlative satellite and ground-based total and tropospheric ozone measurements at time scales from daily averages to monthly means. The comparisons show good agreement with increased differences at high latitudes. The agreement improves if we only accept retrievals derived from the EPIC 317 nm triplet and limit solar zenith and satellite looking angles to 70°. With such filtering in place, the comparisons of EPIC total column ozone retrievals with correlative satellite and ground-based data show mean differences within ±5-7 Dobson Units (or 1.5–2.5%). The biases with other satellite instruments tend to be mostly negative in the Southern Hemisphere while there are no clear latitudinal patterns in ground-based comparisons. Evaluation of the EPIC ozone time series at different ground-based stations with the correlative ground-based and satellite instruments and ozonesondes demonstrated good consistency in capturing ozone variations at daily, weekly and monthly scales with a persistently high correlation (r2 &gt; 0.9) for total and tropospheric columns. We examined EPIC tropospheric ozone columns by comparing with ozonesondes at 12 stations and found that differences in tropospheric column ozone are within ±2.5 DU (or ∼±10%) after removing a constant 3 DU offset at all stations between EPIC and sondes. The analysis of the time series of zonally averaged EPIC tropospheric ozone revealed a statistically significant drop of ∼2–4 DU (∼5–10%) over the entire NH in spring and summer of 2020. This drop in tropospheric ozone is partially related to the unprecedented Arctic stratospheric ozone losses in winter-spring 2019/2020 and reductions in ozone precursor pollutants due to the COVID-19 pandemic.
Photoelastic Properties of Trigonal Crystals
Authors: Mytsyk Bohdan , Demyanyshyn Nataliya , Andrushchak Anatoliy , Buryy Oleh 
Published: September 2021

All possible experimental geometries of the piezo-optic effect in crystals of trigonal symmetry are studied in detail through the interferometric technique, and the corresponding expressions for the calculation of piezo-optic coefficients (POCs) πim and some sums of πim based on experimental data obtained from the samples of direct and X/45°-cuts are given. The reliability of the values of POCs is proven by the convergence of πim obtained from different experimental geometries as well as by the convergence of some sums of POCs. Because both the signs and the absolute values of POCs π14 and π41 are defined by the choice of the right crystal-physics coordinate system, we here use the system whereby the condition S14 > 0 is fulfilled (S14 is an elastic compliance coefficient). The absolute value and the sign of S14 are determined by piezo-optic interferometric method from two experimental geometries. The errors of POCs are calculated as mean square values of the errors of the half-wave stresses and the elastic term. All components of the matrix of elasto-optic coefficients pin are calculated based on POCs and elastic stiffness coefficients. The technique is tested on LiTaO3 crystal. The obtained results are compared with the corresponding data for trigonal LiNbO3 and Ca3TaGa3Si2O14 crystals.
TEKNIK BIOLOGIC NURTURING BABY LED FEEDING DAN FINGER HOLD TERHADAP PERUBAHAN RASA NYERI PADA IBU POST SECTIO CAESAREA
Authors: Rusmilawati Ni Wayan , Ririn Sri Wulandari Made , Ratih Agustini I G A , Putu Indah Purnamayanthi Pande 
Published: September 2021

Pelayanan kesehatan ibu dimulai selama masa kehamilan, persalinan salah satunya adalah dengan cara sectio caesarea. Permasalahan yang terjadi post sectio caesarea adalah nyeri. Penatalaksanaan untuk mengurangi rasa nyeri post sectio caesarea yang adalah relaksasi finger hold. Teknik relaksasi yang juga dianjurkan adalah menyusui dengan posisi biologic nurturing baby led feeding. Tujuan penelitian untuk mengetahui pengaruh teknik biologic nurturing baby led feeding dan finger hold terhadap perubahan rasa nyeri pada ibu post sectio caesarea. Penelitian ini merupakan penelitian kuantitatif true experimental dengan desain pretest-posttest with control. Teknik sampling yang digunakan dalam penelitian ini adalah probability sampling dengan simple random sampling. Populasi adalah ibu post sectio caesarea sebanyak 36 orang yang terbagi ke dalam dua kelompok yaitu kelompok kontrol sebanyak 18 orang dan kelompok perlakuan sebanyak 18 orang. Instrumen penelitian menggunakan lembar observasi intensitas nyeri deskriptif. Analisa data bivariat menggunakan analisis Mann-Whitney. Hasil analisis menunjukkan nilai p value adalah 0,001 artinya ada pengaruh teknik biologic nurturing baby led feeding dan finger hold terhadap perubahan rasa nyeri pada ibu post sectio caesarea. Hasil penelitian dapat dijadikan acuan dalam asuhan keperawatan ibu post sectio caesarea dalam mengatasi rasa nyeri yang dialami

Maternal health services begin during pregnancy, one of which is delivery by means of cesarean section. The problem that occurs post sectio caesarea is pain. Management to reduce post sectio caesarean pain is finger hold relaxation. The relaxation technique that also recommended is breastfeeding with the biological nurturing position of the baby led feeding. The purpose of this study was to determine the effect of biologic nurturing baby led feeding and finger hold techniques on changes in pain in post sectio caesarean mothers.This research is a true experimental quantitative research with a pretest - posttest design with control. The sampling technique used in this study is probability sampling by simple random sampling. The number of samples in this study were 36 people who were divided into two groups, namely the control group as many as 18 people and the treatment group as many as 18 people. Bivariate analysis of data using the Mann-Whitney. The results of the Mann Whitney showed that the p value was 0.001 meaning that the hypothesis of this study was accepted, which means that there was an effect of biological nurturing baby led feeding and finger hold techniques on changes in pain in post-sectio caesarean mothers. The results of this study are expected to be used as a reference in providing nursing care so that it can improve the quality of post-caesarean post section maternal services in dealing with pain experienced.
AKUPUNTUR METODE YNSA DAN HIPNOTERAPI TERHADAP KECERDASAN INTELEKTUAL (IQ) DAN KECERDASAN EMOSIONAL (EQ) ANAK
Authors: Christiyawati Maria Dewi , Estuningsih E 
Published: September 2021

Kecerdasan intelektual (IQ) membantu seseorang untuk mampu bertindak secara terarah, berpikir secara rasional, dan menghadapi lingkungannya secara efektif. Sama dengan IQ, kecerdasan emosional (EQ) penting bagi keberhasilan seseorang untuk berempati, mengungkapkan dan memahami perasaaan, mengendalikan amarah, kemandirian, serta beradaptasi. Beberapa upaya untuk meningkatkan IQ dan EQ adalah terapi akupuntur dengan metode Yamamoto New Scalp Acupuncture (YNSA) dan hipnoterapi. Tujuan penelitian untuk mengetahui pengaruh terapi akupuntur metode YNSA dan hipnoterapi untuk meningkatkan IQ dan EQ anak di TK Kanisius, Sukoharjo. Metode penelitian merupakan penelitian kuantitatif pre dan post test design dengan kontrol secara cross-sectional. Analisis statistik menggunakan uji Mann Whitney dan uji paired T- test. Hasil penelitian menunjukkan untuk p value pada variabel IQ yaitu komponen pemahaman: 0.018, ingatan: 0.000, logika: 0.174, daya cipta: 0.361, dan pengetahuan umum: 0.024. Hasil p value pada variabel EQ yaitu komponen pengaturan diri: 0.017, interaksi sosial: 0.661, kemandirian: 0.000, kompetisi: 0.192, kepekaan: 0.000. Kesimpulan penelitian ini adalah ada pengaruh terapi akupuntur metode YNSA dan hipnoterapi terhadap peningkatan IQ (pemahaman, ingatan, pengetahuan umum) dan EQ (pengaturan diri, kemandirian dan kepekaan) pada anak.
Intellectual intelligence (IQ) helps someone to act purposefully, think rationally, and deal with his environment effectively. Similar to IQ, emotional intelligence (EQ) is important for a person's success in empathizing, expressing and understanding feelings, controlling anger, independence, and adapting. Some efforts to increase IQ and EQ are acupuncture therapy with the Yamamoto New Scalp Acupuncture (YNSA) method and hypnotherapy. The purpose of this study was to determine the effect of acupuncture therapy using the YNSA method and hypnotherapy to increase the IQ and EQ of children at Kanisius Kindergarten, Sukoharjo. The research method was quantitative pre and post test design with cross-sectional control. Statistical analysis was using Mann Whitney test and paired T-test. The results showed that p value on the IQ variable, the components of understanding: 0.018, memory: 0.000, logic: 0.174, creativity: 0.361, and general knowledge: 0.024. The p value on the EQ variable are self-regulation components: 0.017, social interaction: 0.661, independence: 0.000, competition: 0.192, sensitivity: 0.000. The conclusion of this study is there was an effect of YNSA method acupuncture therapy and hypnotherapy on increasing IQ (understanding, memory, general knowledge) and EQ (self-regulation, independence and sensitivity) in children.
ANÁLISE DA VULNERABILIDADE FAMILIAR EM DOMICÍLIOS SUBMETIDOS À VISITA DOMICILIAR EM CIDADE NO INTERIOR DO CEARÁ
Authors: Morais João Lucas Araújo , Morais Ivna Maria de Oliveira , Morais Neto Francisco Willame , Gomes Sócrates Belém , Gomes Antonia Edna Belém , Campos Jocileide Sales 
Published: September 2021

Introdução: Na década de 80 foi criado o Sistema Único de Saúde, fundamentado em três princípios doutrinários: Universalidade, Integralidade e Equidade. Com base nesses princípios foi instituída a Visita Domiciliar (VD) que consiste no atendimento aos pacientes incapazes de comparecer à Unidade Básica de Saúde. Objetivo: Esse estudo visa avaliar o risco de vulnerabilidade familiar em residências submetidas à VD. Método: Foi realizada uma capacitação com os Agentes Comunitários de Saúde na cidade de Mulungu/Ceará para a aplicação de Escala de Coelho e Savassi nos domicílios. Resultados: A escala foi aplicada em 40 residências, abrangendo 100% do território. O estado de risco dos indivíduos foi dividido em 3 grupos: R1, R2 e R3, sendo R1 o de menor risco e R3 o de maior risco. Na análise dos dados foram encontrados 24 indivíduos em R3, 8 em R2 e 12 em R1, com predomínio de comorbidades como: >70 anos, ser acamado, hipertensão e analfabetismo. Conclusão: Esse estudo permite uma visão sobre a situação dos pacientes submetidos à VD para a realização do planejamento em saúde do município, organizando as devidas prioridades na estratégia saúde da família.
EVALUASI PENERAPAN IT GOVERNANCE DENGAN MENGGUNAKAN KERANGKA KERJA COBIT 5 PADA LAYANAN PUBLIK
Authors: Ibrahim Ibrahim , Hidayat Rahmat 
Published: September 2021

Telah dilakukan penelitian tentang evaluasi penerapan Information Technology (IT) governance pada salah sektor layanan publik, dengan menggunakan kerangka kerja COBIT 5. Evaluasi ini dilakukan untuk memastikan kinerja implementasi teknologi informasi (TI) dapat dirasakan manfaatnya oleh pemangku kepentingan dalam rangka penyediaan informasi yang cepat, akurat dan efektif dan efisien untuk mendukung pengambilan keputusan. Penelitian ini menggunakan COBIT 5 khususnya terkait dengan proses-proses delivery, service and support (DSS). Hasil penelitian menunjukkan bahwa nilai process capability level domain DSS adalah 3,3 (established), yang terdiri dari DSS1=4, DSS2=4, DSS3=4, DSS4=3, DSS5=3 dan DSS6=2. Tiga proses telah menuhi target kinerja yakni DSS01, DSS02, DSS03 dan DSS04. Sedangkan tiga proses lainnya masih dibawah target kinerja yakni DSS04, DSS05 dan DSS06, sehingga perlu dilakukan perbaikan. Rekomendasi perbaikan secara umum meliputi penyusunan dokumen BCP dan DRP, pengendalian informasi dan data bisnis , audit dan sertifikasi berdasarkan sistem manajemen keamanan informasi (ISMS)ISO/IEC 27001:2017.

Kata Kunci :
IT Governance, COBIT 5, Process Capability Level
EFIKASI HERBISIDA ISOPROPILAMINA GLIFOSAT 240 g l-1 TERHADAP PERTUMBUHAN GULMA DI PERKEBUNAN KELAPA SAWIT (Elaeis guineensis Jacq) TANAMAN MENGHASILKAN
Authors: Yaman Wasri 
Published: September 2021

Oil palm (Elaeis guineensis Jacq.) Is one of the most widely cultivated plantation crops in Indonesia. The decrease in productivity of oil palm is caused by presence of weeds around the plant that can be controled. One of the most commonly used controls is the use of the isopropylamine glyphosate herbicide. This research aims to determine the dosage of the Isopropylamine glyphosate herbicide which is oil palm yields. Determining changes in weed composition after application of Isopropylamine glyphosate herbicide in oil palm yields. Determining whether phytotoxicity occurs in oil palm yields after application of the Isopropylamine glyphosate herbicide. This research was conducted in oil palm plantations owned by farmers in Jontor Kenangasari Village, Seputih Surabaya District, Central Lampung Regency and the Weed Laboratory of the Faculty of Agriculture, University of Lampung, Gedong Meneng, Bandar Lampung. The research was conducted using a randomized block design (RBD) with 6 treatments and 4 replications, namely various doses of isopropylamine glyphosate (360, 600, 480, and 720 g ha-1), manual weeding, and control. Homogeneity of variance was tested using the Bartlet test, additivity was tested by the Tukey test, and the mean difference was tested by the Least Significant Difference Test (LSD) at the 5% level. The results showed that: (1) The isopropylamine glyphosate herbicide dose of 480-720 g ha-1 is effective in controlling total weeds, grasses weeds, Brachiaria mutica weeds and Mikania micrantha weeds up to 12 MSA and the herbicide dose of 600-720 g ha-1 is effective in controlling wide leaf weeds, and Cyrtococcum acrescens weeds up to 8 MSA, (2) The isopropylamine glyphosate herbicide 360- 720 g ha-1 causes changes in weed composition at 4, 8, and 12 MSA, and (3) Application of the isopropylamine glyphosate herbicide 360 - 720 g ha-1 on plant plates did not cause poisoning to oil palm plants.
Analisis Penggunaan Aksara Sasak Dalam Keseharian Masyarakat Lombok Barat Di Era Globalisasi
Authors: Ismi Haerul , Asrin Asrin , Widodo Arif 
Published: September 2021

Aksara sasak merupakan warisan kebudayaan suku sasak yang memiliki identitas, keunikan tersendiri dan patut dilestarikan. Keberadaan aksara sasak saat ini semakin terkikis seiring perkembangan globalisasi dan modernisasi di tengah masyarakat. Bahkan banyak generasi muda tidak mengetahui aksara sasak baik itu bentuk tulisan maupun pelafalannya. Penelitian ini bertujuan untuk mengetahui sejauh mana aksara sasak ini masih bertahan dalam lingkup masyarakat di era globalisasi dan modernisasi sekarang. Penelitian ini menggunakan metode deskriptif kualitatif. Pengumpulan data menggunakan survey dan wawancara. Responden penelitian ini adalah orang tua dan remaja. Masalah yang dikaji adalah bagaimana minat generasi muda dalam mengetahui aksara sasak? Hasil penelitian ini menunjukkan bahwa minat generasi muda dalam mengetahui aksara sasak ternyata sangat rendah. Indikator yang menunjukkan rendahnya minat generasi muda dalam mengetahui aksara sasak antara lain: generasi muda menganggap aksara sasak kuno dan kampungan, terjadinnya globalisasi dan modernisasi, kurangnya penyalur cerita dari orang tua zaman dahulu. Berdasarkan hasil penelitian yang telah dilakukan perlu beberapa upaya untuk membangkitkan minat generasi muda dalam mengetahui aksara sasak agar tidak terkikis salah satunya dengan pemanfaatan teknologi informasi seperti, membuat konten kreatif mengenai aksara sasak kemudian menguploadnya di akun youtube atau instagram untuk menarik minat para pemuda, membuat buku khusus tentang aksara sasak