bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Novel Application of Asphalt in Cross-Linked Polyethylene Composite
Authors: Liao Yi , Lai Shuangxin , Yang Shuangqiao , Liu Jinjing , bai shibing 
Published: May 2021

Abstract
The cross-linked polyethylene (XLPE) cables are widely used as an important basic material for power transportation. However, the cross-linked network structure caused challenge in the recycling of waste XLPE, which usually be treated by incineration and landfilling. In this research, XLPE was de-crosslinked via solid-state shear milling (S3M) and the asphalt was used as plasticizer during the thermoplastic processing. To deeply understand the influence of asphalt on the matrix, the compatibility, dispersion, and rheological properties of composites were characterized. Due to the good compatibility between de-crosslinked XLPE and asphalt, the viscosity of the composites decreased significantly. Some sea-island structure also formed in composites, which increased the toughness of the composites and the elongation at break reach as high as 322%. The use of asphalt to achieve the processing performance of de-crosslinked XLPE powder was highly effective and composites can be processed by ordinary polymer processing equipment. Furthermore, the prepared composites show potential application in the field of waterproofing which could recycle of waste XLPE cables in large-scale.
Microvirga Jeongseonensis Sp. Nov., New Species Isolated From Soil in South Korea
Authors: Maeng Soohyun , Park Yuna , Oh Hyejin , Bang Minji , Baigalmaa Jigden , Bai Jaewoo , Kim Myung Kyum 
Published: May 2021

Abstract
A novel Gram-stain-negative, aerobic, rod-shaped, convex, and light pink-colored strain BT688T was isolated from a soil sample collected in Jeongseon city, South Korea. Phylogenetic analysis based on 16S rRNA gene sequence revealed that strain BT688T belongs to a distinct lineage within the genus Microvirga (family Methylobacteriaceae, order Rhizobiales, class Alpha Proteobacteria, phylum Proteobacteria). The 16S rRNA gene sequence similarity between strain BT688T and Microvirga aerilata 5420S-16T was 98.5%. Strain BT688T had Q-10 as a major respiratory quinone and the major polar lipids of strain BT688T was diphosphatidilglycerol (DPG), phosphatidylglycerol (PG), phosphatidylethanolamine (PE), and phosphatidylcholine (PC). The major cellular fatty acids of strain BT688T were C18:1 ω7c (76.0%) and summed feature 3 (9.6%).Based on the polyphasic characteristics, strain BT688T can be suggested as a novel bacterial species within the genus Microvirga and the proposed name is Microvirga jeongseonensis. The type strain of Microvirga jeongseonensis is BT688T (= KCTC XXXXT=NBRC 114857 T).
Systemic Analysis of the DNA Replication Regulators Origin Recognition Complex in Lung Adenocarcinomas Identifies Prognostic and Expression Significance
Authors: Chen Juan , Zou Juan , Zeng Juan , Zeng Tian , Hu Qi-hao , Bai Jun-hui , Tang Min , Li Yu-kun 
Published: May 2021

Abstract
Background: Origin recognition complex (ORC) 1, ORC2, ORC3, ORC4, ORC5 and ORC6, form a replication-initiator complex to mediate DNA replication, which play a key role in carcinogenesis, while their role in lung adenocarcinomas (LUAD) remains poorly understood.Methods: We confirmed the transcriptional and post-transcriptional levels, DNA alteration, DNA methylation, miRNA network, protein structure, PPI network, functional enrichment, immune infiltration and prognostic value of ORCs in LUAD based on Oncomine, GEPIA, HPA, cBioportal, TCGA, GeneMANIA, Metascape, KM-plot, GENT2, and TIMER database. Results: ORC mRNA and protein were both enhanced obviously based on Oncomine, Ualcan, GEPIA, TCGA and HPA database. Furthermore, ORC1 and ORC6 have significant prognostic values for LUAD patients based on GEPIA database. Protein structure, PPI network, functional enrichment and immune infiltration analysis indicated that ORC complex cooperatively accelerate the LUAD development by promoting DNA replication, cellular senescence and metabolic process. Conclusion: the ORC complex has an important prognostic and expression significance for LUAD patients.
Novel Immune-Related Gene Signature for Risk Stratification and Prognosis of Survival in Estrogen Receptor (ER) or Progesterone Receptor (PR) Positive and Human Epidermal Growth Factor Receptor 2 (HER2) Negative Breast Cancer
Authors: Wang Wei , Jiang Hongnan , Gao Yanrong 
Published: May 2021

Abstract
Background: Although intrinsic molecular subtype has been extensively used, the risk stratification have not been fully elucidated in estrogen receptor (ER) or progesterone receptor (PR) positive and human epidermal growth factor receptor 2 (HER2) negative breast cancer. Methods: RNA transcriptional data from The Cancer Genome Atlas (TCGA), METABRIC and GEO were used. Immune-related genes were obtained from the datasets and literature search. Univariate, lasso regression and multivariate cox regression were employed to identify prognostic immune-related genes and establish the risk signature. Relationships between the risk signature and clinical parameters, tumor-infiltrating immune cell abundances and cancer phenotypes were further evaluated.Results: Noted, 102 immune-related prognostic genes were identified in METABRIC dataset by univariate cox analysis. Consecutively, 7 immune genes (SHMT2, AGA, COL17A1, FLT3, SLC7A2, ATP6AP1 and CCL19) were selected as risk signature by lasso regression and multivariate cox analysis. Its performance was further verified in TCGA,GSE20685 and GSE9195 datasets. Multivariate Cox regression indicated that the risk signature was an independent predictor. The prognostic signature showed significant correlation with intrinsic molecular subtypes, 70-gene signature and tamoxifen resistance signature. The CIBERSORT algorithm revealed that CD4+ memory T cells were significant higher in low-risk group. Conversely, M0-type macrophages were significant higher in high-risk group in both TCGA and METABRIC cohorts, which may have effect on the prognosis. Furthermore, we found that low-risk group may be associated with immune-related pathway and high-risk group was with cell cycle-related pathway, which also showed impact on the prognosis.Conclusion: The present study constructed a robust seven immune-related gene signature and established an effective method in risk stratification and prediction of clinical outcome in ER or PR positive and HER2 negative breast cancer.
Intergenerational Effects of Violence on Women’s Perinatal Wellbeing and Infant Health Outcomes: Evidence from a Birth Cohort Study in Central Vietnam
Authors: Do Phuc Huyen , Baker Philip RA , Vo Van Thang , Murray Aja , Murray Linda , Valdebenito Sara , Eisner Manuel , Tran Bach Xuan , Dunne Michael P 
Published: May 2021

Abstract
Background: This study examined the intergenerational effects of being exposed to childhood maltreatment (CM) and prenatal intimate partner violence (p-IPV) on perinatal mental distress and birth outcomes in central Vietnam. Methods: A birth cohort study in Hue City, Vietnam was conducted with 150 women in the third trimester of pregnancy (Wave 1) and three months after childbirth (Wave 2). Using multivariable logistic regression models, augmented inverse-probability-weighted estimators and structural equation modelling (SEM), we analyzed a theoretical model by evaluating adjusted risk differences and pathways between CM, p-IPV and subsequent perinatal adversity and indicators of infant health problems. Results: One in two pregnant women experienced at least one form of CM (55.03%) and one in ten pregnant women experienced both CM and p-IPV (10.67%). Mothers who experienced p-IPV or witnessed IPV as a child were approximately twice as likely to experience poor mental health during pregnancy [ARR 1.94, 95% CI (1.20-3.15)]. Infants had a two-fold higher risk of adverse birth outcomes (low birth weight, preterm birth, admission to neonatal intensive care) [ARR 2.45 95% CI (1.42, 4.25)] if their mothers experienced any form of p-IPV, with greater risk if their mothers were exposed to both CM and p-IPV [ARR 3.45 95% CI (1.40, 8.53)]. Notably, significant pathways to p-IPV were found via adverse childhood experience (ACE) events (β = 0.13), neighborhood disorder (β = 0.14) and partner support (β = -1.3). Conclusion: These results emphasize the detrimental and prolonged nature of the effect of violence during childhood and pregnancy. Exposure to childhood maltreatment and violence during pregnancy increases the risk of maternal mental health difficulties and adverse birth outcomes. Antenatal care systems need to be responsive to women’s previous experiences of violence and maternal mental health. The significant protective role of partner support and social support should also be considered when designing tailored interventions to address violence during pregnancy.
A Trending Study On The Neutrosophication Of Transform
Authors: R Poornima 
Published: May 2021

Abstract
The present study focuses on the neutrosophication of Z-Transform , it is developed and various properties like neutrosophic Z-Transform linearity, neutrosophic Z-Transform damping rule, neutrosophic Z-Transform shifting theorem, neutrosophic Z-Transform’s initial and final value theorem are discussed under this method. The results of the properties are proposed and numerical example have been illustrated.
Function Of Surfactants In Immobilization of Cellulase And Multiphase Hydrolysis: A Review
Authors: Wang Zhiquan , Wu Deyi , Wang Xinze , Kong Hainan 
Published: May 2021

Abstract
Surfactants, especially non-ionic surfactants, play an important role in the preparation of nanocarriers and can also promote the enzymatic hydrolysis of lignocellulose. A broad overview of the current status of surfactants on the immobilization of cellulase is provided in this review. In addition, the restricting factors in cellulase immobilization in the complex multiphase hydrolysis system are discussed, including the carrier structure characteristics, solid-solid contact obstacles, external diffusion resistance, limited recycling frequency, and invalid combination of enzyme active centers. Furthermore, promising prospects of cellulase-oriented immobilization are proposed, including the hydrophilic-hydrophobic interaction of surfactants and cellulase in the oil-water reaction system, the reversed micelle system of surfactants, and the possible oriented immobilization mechanism.
Maternal Psoriasis Magnitude The Risk Of Pregnancy Complications In Women: A Systematic Review And Meta-Analysis
Authors: Kupwiwat Rosalyn , Deewongkij Poonnapa , Wannigama Dhammika Leshan , Hurst Cameron , Chakkavitthumrong Panlop 
Published: May 2021

Abstract
Psoriasis is a chronic inflammatory disease with significant physical and psychological distress. As there are conflicting data from published literatures on the relationship between psoriasis and pregnancy. We hypothesized that the dysregulation of the immune system in psoriasis, will result in negative impact regarding to fetomaternal morbidity and mortality. Therefore, objective of this systematic review and meta-analysis is to assess the effect of maternal psoriasis and adverse pregnancy outcomes. We searched PubMed, Web of Science, SCOPUS, and Cochrane Library for published articles from January 1980 to December 2020. Total 1592 citations and identified studies examining outcomes of pregnancies complicated by psoriasis. Seventeen studies were included with a total of 44,249 pregnancies in women with psoriasis and 47,807,880 pregnancies in women without the disease. Random-effect models were used to generate pool odds ratios. We found a higher odd of pregnancy-related complication in women with psoriasis compared with non-disease controls; 1.47 for pregnancy-related hypertension (9 studies; 95%CI 1.16–1.87), 1.70 for gestational diabetes (7 studies; 95%CI 1.34–2.15), 1.28 for preterm (10 studies; 95%CI 1.14–1.44), and 1.35 for cesarean section (10 studies; 95%CI 1.22–1.50). The results of this meta-analysis confirm that psoriasis is a risk factor for pregnancy-related hypertension, gestational diabetes, and preterm labor.
Abdominal Obesity Affects Short-Term After Total Hip Arthroplasty: A Retrospective Study
Authors: Wang xiang , Yang Ze , Zhang Yang , Ge Qinwen , Shen Jing , Ji Wei-feng 
Published: May 2021

Abstract
Background: At present, there are many clinical studies on the impact of obesity on postoperative function following total hip arthroplasty, but their conclusions are different and even contradictory. As abdominal obesity (AO), which is closely related to obesity, we know very little about its impact on postoperative function following total hip arthroplasty.Methods: Sixty-four patients were included in this prospective randomized controlled trial. Divided them into AO group (WC ≥ 90 cm for men and ≥ 85 cm for women) and non-AO group (WC ≤ 90 cm for men and ≤ 85 cm for women). Preoperative assessment included numerical pain rating, the Oxford Hip Score, 6-minute walk test and repeated at 6,12 months postoperatively. Postoperative assessment included the anteversion and inclination of the acetabular prosthesis, satisfaction at 12 months.Results：The hip joint function of both groups has been significantly improved at 1 year postoperatively. No significant differences were found in hip pain or function between the AO and non-AO groups. However, AO patients had poorer walking capacity (p=0.001).Conclusion: AO does not increase the complications after THA, nor does it have a significant impact on the function after THA, but it seems to have a negative effect on the improvement of walking ability.
Toll-Like Receptors in InflammAging at Ocular Surface.
Authors: Zazzo Antonio , Piano Maria , Micera Alessandra , Mori Tommaso , Coassin Marco 
Published: May 2021

Abstract
Purpose: To evaluate changes in Toll Like Receptors expression at the ocular surface of healthy control volunteers within age. Methods: 51 volunteers were enrolled in a pilot observational study. Clinical (OSDI questionnaire, Schirmer test and BUT) and Biomolecular (ICAM1, Goblet cells) biomarkers were assessed in all subjects. Temporal Conjunctival imprints were used for molecular analysis while nasal ones were harvested for epifluorescence microscopy. Results: Within the age in our sample OSDI score increases, T-BUT values decrease, and goblet cells showed a decreasing trend. Relative real time PCR detected up-regulation of TLR2 and down-regulation of TLR7, TLR8 and MyD88 transcripts. Immunofluorescence data corroborated the PCR results reporting increased TLR2 and decreased TLR7 and TLR8 expression in elder population. A direct correlation was showed between increasing ICAM and increasing TLR2 changes with age. Conclusion: Changes in TLR expression are associated with aging, suggesting physiological role of TLRs in modulating innate and adaptive ocular surface immunity. TLRs age related changes may participate to the failure of ocular surface homeostatic mechanisms with inflammAging.
Study on the Anti-Aging Physiological Characteristics and Molecular Mechanism of Camellia Oleifera
Authors: Chen Yongzhong , Chen Jianjun , Zhang Zhen , Xu Yanming , He Zhilong , Liu Caixia , Wang Rui , Wang Xiangnan , Peng Yinghe , Peng Shaofeng , Chen Longshen , Ma Li , Li Zhigang , Tang Wei 
Published: May 2021

Abstract
To study the physiological and molecular regulating mechanism of ancient Camellia oleifera which kept a exuberant vitality for more than one hundred years, leaves of 30a year old and > 100 year old Camellia oleifera were selected as targets. On the basis of the study of the generation and the clearance of reactive oxygen species, sequencing analysis of the transcriptome and expression profiling by high throughput sequencing analysis technique was conducted to study differentially expressed functional genes related to the tree age. It showed that the chlorophyll content and enzyme activities increased in ancient Camellia oleifera leaves. Expression of chlorophyll a/b binding protein gene, auxin related gene, the signal transduction factor and the transcription factor gene in ancient trees were all higher than mature tree. The down regulated gene expression of inductive genes related to protein degradation in ancient tree. Under the comprehensive function of those factors, ancient Camellia oleifera leaves still kept an exuberant vitality which was very useful for studies of stress resistance molecular biology and genetic improvement of Camellia oleifera.
Is there Universality in the Dielectric Response of Polar Glass Formers?
Authors: Ngai K. L. , Wojnarowska Zaneta , Paluch Marian 
Published: May 2021

Abstract
The frequency dispersion of structural α-relaxation obtained from broadband dielectric spectroscopy measurements is relatively narrow in many polar glass-formers. On the other hand, it becomes much broader when probed by other techniques, including photon correlation spectroscopy (PCS), nuclear magnetic resonance (NMR), and mechanical shear modulus. Therefore, the dynamics of glass-formers observed by dielectric permittivity spectroscopy (DS) is called into question. Herein we propose a way to resolve this problem. First, we point out an unresolved Johari-Goldstein (JG) β-relaxation is present nearby the α-relaxation in these polar glass-formers. The dielectric relaxation strength of the JG β-relaxation is sufficiently weak compared to the α-relaxation so that the narrow dielectric frequency dispersion faithfully represents the dynamic heterogeneity and cooperativity of the α-relaxation. However, when the other techniques are used to probe the same glass-former, there is a reduction of relaxation strength of α-relaxation relative to that of the JG β-relaxation. Additionally, the separation between the α and the JG β relaxations in dielectric permittivity) decreases when probed by mechanical shear modulus. These changes in relation of α- to JG β-relaxation, when examined by the other techniques, engender the non-negligible contribution of the latter to the former. Hence the apparent α-relaxation is broader than observed by the dielectric permittivity. The broadening is artificial because it is due to a confluence of the α and JG β relaxations with a disparity in their relaxation strengths much less when the other techniques than by dielectric permittivity are used. This explanation is supported by showing the α-relaxation of polar glass-formers becomes broader when the dielectric data are represented in terms of the electric modulus instead of permittivity. The broadening, in this case, is again due to a reduction of the relaxation strength of the α-relaxation relative to that of the JG β-relaxation in the electric modulus representation. A corollary of the explanation applicable to weakly polar glass-formers having JG β-relaxation widely separated from the α-relaxation is the prediction that the frequency dispersion of dielectric α-relaxation is nearly the same as that of the electric modulus, and there is no significant additional broadening when probed by the other techniques. A host of experimental data from the literature and our new measurements are given to support the explanation for polar glass-formers and the ancillary prediction for weakly polar glass-formers. Thus the narrow frequency dispersion of the intense relaxation in polar glass-formers observed by dielectric permittivity is real and genuinely represents the dynamically heterogeneous and cooperative dynamics of α-relaxation. By contrast, the broad dispersion found by the other techniques is artificial and misleading.
Adsorption study of toxic metal ions using functionalized 3D mesostructured silica
Authors: Torad Nagy , El-Nasr Ahmed Abu , Salahuddin Nehal , ayad mohamad 
Published: May 2021

Abstract
Mesoporous silica KIT-6 was chemically modified using 3-mercaptopropyltriethoxysilane (3-MPTS) via post-grafting method to prepare functionalized mesoporous KIT-6-SO3H with highly acidic ‒SO3H groups. Thin layers of KIT-6-SO3H coating onto quartz crystal microbalance (QCM) electrodes are employed as a meso-KIT-6-QCM sensor for the adsorptive removal of Pd(II), Cd(II) and Cs(I) ions with a high detection sensitivity. From ICP-OES measurements, the calculated adsorption capacity (Qe) values are much coincide with that obtained from QCM sensor. Due to the synergetic cooperation between high surface area, large pore volumes and active ‒SO3H groups, KIT-6-SO3H exhibited a remarkable adsorption capacity for metal ions. The effect of initial solution pH on the metal ions uptake was carefully studied. Kinetics and isotherm studies further reveal that adsorption of metal ions by KIT-6-SO3H obeys second-order kinetic and Langmuir isotherm, respectively.
Light-powered Self-excited Coupled Oscillators in Huygens ’ Synchrony
Authors: Cheng Quanbao , Li Kai 
Published: May 2021

Abstract
Self-excited motions have the advantages of actively collecting energy from the environment, autonomy, making equipment portable and so on, and a great number of self-excited motion modes have recently been developed which greatly expand the application in active machines. However, there are few studies on the synchronization and group behaviors of self-excited coupled oscillators, which are common in nature. Based on light-powered self-excited oscillator composed of liquid crystal elastomer (LCE) bars, the synchronization of two self-excited coupled oscillators is theoretically studied. Numerical calculations show that self-excited oscillations of the system have two synchronization modes: in-phase mode and anti-phase mode. The time histories of various quantities are calculated to elucidate the mechanism of self-excited oscillation and synchronization. Furthermore, the effects of initial conditions and interaction on the two synchronization modes of the self-excited oscillation are investigated extensively. For strong interactions, the system always develops into in-phase synchronization mode, while for weak interaction, the system will evolve into anti-phase synchronization mode. Meanwhile, the initial condition generally does not affect the synchronization mode and its amplitude. This work will deepen people's understanding of synchronization behaviors of self-excited coupled oscillators, and provide promising applications in energy harvesting, signal monitoring, soft robotics and medical equipment.
Synthesis of Novel Cationic Bleach Activator, N-[4-(N,N,N)-Triethylammoniumchloride- Butanoyl] Butyrolactam, for Cellulose : Optimization and Theoretical Limitations
Authors: Altay Pelin , Yildiirm Erol , Gursoy Nevin Cigdem , Hauser Peter J. , El-Shafei Ahmed 
Published: May 2021

Abstract
Activated bleach systems have the potential to produce more efficient kinetically potent bleaching systems through increased oxidation rates with reducing energy cost, saving time and, hence, causing less cellulose polymer chains damage or degradation than conventional hot peroxide bleaching. In this study, a novel cationic bleach activator, N-[4-(N,N,N)-triethylammoniumchloride- butanoyl] butyrolactam (TBUCB), was synthesized and applied for hot peroxide bleaching to determine the optimum bleaching conditions and theoretical limitations of TBUCB for low temperature bleaching of cellulose. First principles density functional theory (DFT) calculations were performed to elucidate the reaction mechanism via identifying plausible transition state(s) of the nucleophilic attack of perhydroxyl anion (HOO-) with different carbonyl carbons and identifying the advantages and limitations of TBUCB activator for hydrogen peroxide bleaching for cellulose. The results obtained showed that whiteness index greater than 80 for cellulose can be achieved by using activated H2O2-TBUCB bleaching system at lower temperature, providing reduced energy cost while maintaining the integrity of cellulose polymer chains.