bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ortognatik Cerrahi Tedavi ve Yumuşak Dokular Üzerindeki Etkisi
Authors: ÇOBAN Gökhan , YAVUZ İbrahim 
Published: April 2021

Büyüme gelişimini tamamlamış hastalarda tek başına ortodontik düzeltimin kapasitesini aşan şiddetli iskeletsel uyumsuzlukların tedavisinde kullanılan ortodontik ve cerrahi prosedürler ortognatik cerrahi olarak adlandırılmaktadır. Bu tedavinin sonucunda kabul edilebilir ve dengeli bir yüz görünümüne, çiğneme ve konuşma fonksiyonlarına kavuşulması ve hastanın esas şikâyetlerinin çözülmesi amaçlanmalıdır. Yüzün yumuşak doku hatları, altta yatan yüz iskeletini yansıtmaktadır, bu nedenle iskeletsel uyumsuzluklar kaçınılmaz olarak yüzün yumuşak dokularını etkilemektedir. Ortodontinin uzmanlık alanı olarak ilk kurulduğu 1900’lu yıllarda, tedaviler ‘Angle’ın sert doku paradigması’na göre, öncelikli olarak okluzyonun ideale getirilmesi şeklinde planlanmaktaydı; ancak son yıllarda, ortodonti ve ortognatik cerrahi tedavide, dentofasiyal problemlerin yüzün yumuşak dokularındaki tedavisine odaklanan ‘yumuşak doku paradigması’ kabul görmeye başlamıştır. Bu yaklaşımda tedavinin sonunda, öncelikli olarak olarak yüz yumuşak dokularının adaptasyonu ve dengesi amaçlanmaktadır. Bu makalede, ortognatik cerrahi tedavinin endikasyonları, hareket kapasitesi ve yumuşak dokular üzerindeki etkilerini ele alan bir literatür derlemesi sunulmuştur.
A study of ofloxacin and levofloxacin photostability in aqueous solutions
Authors: Frąckowiak Anita , Kamiński Bartosz , Urbaniak Bartosz , Dereziński Paweł , Klupczyńska Agnieszka , Darul-Duszkiewicz Monika , Kokot Zenon J. 
Published: April 2021

Introduction. The photostability is one of the most important properties of drugs. A comprehensive study of ofloxacin (OFX) and levofloxacin (LVX) photostability in aqueous solutions was performed. Ofloxacin is a chemotherapeutic agent belonging to the second generation fluoroquinolones and is a racemate of (R)-(+)-ofloxacin and (S)-(-)-ofloxacin (LVX).Material and Methods. Samples of OFX and LVX were subjected to stress conditions of UV irradiation using a mercury-vapor lamp. The study involved development of enantioselective high-performance liquid chromatography (HPLC) and high-performance capillary electrophoresis (HPCE) methods for separation of OFX enantiomers and their degradation products. These methods were used to monitor the degradation process of OFX and LVX under irradiation and to determine the kinetics of degradation of these antibacterial agents. Moreover, the identification of photoproducts was also attempted. The structure of the main photoproducts was examined by mass spectrometry (MS).Results and Conclusions. Using HPLC method it was possible to observe two products of OFX degradation and only one for LVX, while using HPCE method eight products of OFX degradation and six of LVX were observed. Some of the photoproducts retain character of optically active compounds. The trend of the photodegradation of both tested compounds was described by autocatalytic reaction proceeding according to the Prout-Tompkins model. Some of the products of the decomposition catalyze this reaction. The rate of degradation was similar for both enantiomers but t0.5 was slightly longer for LVX than OFX. Based on MS experiments the photodegradation products of the studied fluoroquinolones and possible pathways of UV induced decay were identified.
Project “Equalizing opportunities – raising competence of children with disabilities”
Authors: Piasecki Bartosz , Mojs Ewa , Sudoł Anna , Samborski Włodzimierz 
Published: April 2021

The project will enable the use of the Tomatis therapy for children with central auditory processing disorders and the introduction of a proprietary curriculum preparing children to learn English in primary school – based on the method that streamlines the auditory analysis, on the proprietary language integration CDs used in the Tomatis method and on individual educational and therapeutic lessons with the teacher. The curriculum will be developed in the course of research under the guidance of prof. UM dr hab. Ewa Mojs from the Poznan University of Medical Sciences. The leader of the consortium implementing the project is the Foundation for Local Activity. The innovation has a high potential for implementation. Applicants to begin with estimate ultimately the ability to implement the program in the first year in 350 schools with the right equipment.
Aborted myocardial infarction in patients undergoing primary percutaneous coronary intervention
Authors: Pyda Małgorzata , Grajek Stefan , Oleśkowska-Florek Weronika , Lesiak Maciej , Siniawski Andrzej , Gwizdała Adrian , Grygier Marek , Araszkiewicz Aleksander 
Published: April 2021

Introduction. The outcome of patients with ST-elevation myocardial infarction (STEMI) strongly depends on a successful reperfusion. In some patients receiving an effective treatment myocardial infarction can be aborted.Aim. The aim of the study was to estimate the incidence, clinical outcome, prognosis and inflammatory response in patients with aborted MI.Material and methods. 119 consecutive patients with STEMI treated with a primary percutaneous coronary intervention (pPCI) were enrolled in the study. Aborted MI was diagnosed when the maximal increase in cardiac enzymes (CK-MB) was up to twice the upper limit of normal (CK-MB ? 50 U/I) and at least 50% reduction of ST-segment deviation was observed within 90 min of pPCI.Results. Aborted MI was diagnosed in 16 subjects (13.4%). Patients with the aborted MI had lower serum troponin I levels (p < 0.0001). The time to treatment was significantly shorter in the aborted MI group (101 min vs. 220 min, p < 0.00001). Patients with aborted MI had a lower corrected TIMI frame count (p < 0.05) and a lower wall motion score index (p < 0.005), less pronounced inflammatory response (lower serum levels of IL-6, p < 0.01, and MCP-1, p < 0.05), higher ejection fraction six months after MI (72% vs. 64%, p < 0.05). None of the aborted MI patients died during the 3-year follow-up, while there were 13 deaths among patients with non-aborted MI.Conclusions. The abortion of myocardial infarction results in a better outcome and more favorable prognosis. An inflammatory response is less pronounced in the aborted MI.
Penggunaan Azotobacter dan Kompos Kulit Buah Kakao Terhadap Pertumbuhan dan Efisiensi Penggunaan Nitrogen Pada Pembibitan Utama Kelapa Sawit
Authors: Tobing Wilda Lumban , Sembiring Mariani 
Published: April 2021

<p>The expansion of oil palm plantations continues to increase so that it requires quality seed. Nurseries need to be done before moving to the field. The use of Azotobacter and cocoa fruit skin compost is one way to increase the growth and nitrogen use efficiency in oil palm in main nursery. This research was aimed to know the growth and nitrogen use efficiency of palm oil in main nursery. This research was conducted on the research area of the Agricultural Agribusiness College of Agriculture Practices (STIPAP) Medan and the Laboratory of Balai Pengkajian Teknologi Pertanian (BPTP) of North Sumatra and the Agricultural Laboratory of the University of North Sumatera from February until Juli 2013. The method used was Randomized Group Design factorial with 3 replications and followed by Duncan test at α=5%. The first factor is Azotobacter including without giving Azotobacter (A0), 20 ml/polybag (A1) and 40 ml/polybag (A2). The second factor is cocoa fruit skin compost, which consists of 3 of them, namely without compost (K0), 125 g/polybag (K1), and 250 g/polybag (K2). The research parameters were plant dry weight (g), nitrogen uptake (mg) and N use efficiency (EPN). The results showed that the use of Azotobacter and cocoa fruit skin compost were able to significantly increasing dry weight of plant and N uptake of oil palm seeds and gave the highest EPN value of 12.93. </p>
PERFORMANCE-BASED BUDGETING EVALUATION IN BONTANG REGIONAL CIVIL SERVICE AGENCY
Authors: Apriani Fajar 
Published: April 2021

<p>The demands of democratization that becoming a global phenomenon that demands the centrality of transparency and accountability in the government sector, including in financial management scope, creating government budgeting management reform in order to increases public participation and increases rule of law in the field of financial aspect, while increasing government performance. Output and outcomes become successive indicator of budgeting implementation by budget user unit. The application of budget performance in financial management of each unit become a curbing expenditure that give priority to the achievement of the results of the planned and allocated input for the execution of the duties and functions of the organization. So basically, the budget performance linking expenditures with results with the benchmarks on the performance of the organization.</p><p><em> </em></p><p><strong>Key words</strong>: Performance budget, public sector budgeting, transparency and accountability, budgeting reform. </p>
POLICY IMPLEMENTATION EFFECTIVENESS OF SUBSIDIZED FERTILIZER ON CROPS IN THE ROKAN HILIR REGENCY
Authors: Yuliani Febri 
Published: April 2021

<p>The role of fertilizers is significant in increasing production andquality of agricultural commodities. Availability of fertilizers to farmers should be conducted to meet six precise principles:precise in time, precise in size, precise in type, precise in place, precise in quality and precise in the right price. By having these principles farmers can apply a balanced fertilizer technology in accordance with specific recommendations. This study was conducted to assess the distribution of fertilizer subsidy policy in Rokan Hilir, Riau province, Indonesia. Rokan Hilir was chosen because nearly 50% of its revenue comes from agriculture, so that understanding the policy of subsidized fertilizer is noteworthy.</p><p>This study was conducted in five districts in the administrative area for Rokan Hilir. The method used in this study is qualitative approach with descriptive research. Data collected in this study consist of primary and secondary data on the effectiveness of policy implementation of fertilizer distribution.</p><p>The results showed that a wide range of alternative approaches have been made to overcome the fertilizer scarcity problems, either by local government or fertilizer manufacturers in Rokan HIlir. The local government asked manufacturers of fertilizers to supply fertilizer in the area in need. This policymay overcome the fertilizers’ shortages and dampen the rise in fertilizer prices in the market. Using this approach, the subsidy was only reflectingdelivery cost to the farmers. However there are some issues that need attention: the audit of the production costs and the operational structure of fertilizer producers need to be performed. This is because there are expenses that irrelevant to the operation of fertilizer producers and large enough. Another concern is no control of fertilizer distribution from upstream to downstream. To overcome this, the Minister of Agriculture should give more authority to local government to control fertilizer distribution. So that the local government head (regent)may distribute the fertilizer subsidy based on land acreage not only acts as fertilizer distributor. Recommendations from this study are also discussed in the article.</p><p> </p><p>Keywords: Policy Implementation, Fertilizer Subsidy, Effectiveness</p>
Diversitas dalam Dunia Kerja: Peluang dan Tantangan bagi Disabilitas
Authors: Aji Abdul Latief Danu , Haryani Tiyas Nur 
Published: April 2021

<p>Diversitas dalam angkatan kerja di era globalisasi saat ini telah mendapatkan perhatian yang lebih. Adanya ratifikasi terhadap konvensi ekosob dan konvensi Hak Asasi Manusia (HAM) menjadi peluang munculnya diversitas dalam angkatan kerja. Indonesia telah meratifikasi konvensi hak-hak disabilitas dan di Kota Surakarta sebdiri telah memiliki Perda No 4 Tahun 2008 Tentang Kesetaraan Kaum Difabel. Artikel ini mendiskusikan mengenai keanekaragaman dalam angkatan kerja yang pada dasarnya memberikan peluang bagi mereka yang memiliki perbedaan fisik dan mental. Namun, dalam sebuah peluang keanekaragaman yang ada tersebut muncul pula tantangan bagi kaum disabilitas dalam memasuki dunia kerja. Tujuan penulisan artikel ini adalah untuk mendiskusikan peluang-peluang bagi kaum dasabilitas dalam memasuki dunia kerja yang telah tertuang dalam berbagai peraturan perUndang-Undanagn baik di tingkat nasional dan daerah sekaligus mendeskripsikan tantangan yang mereka hadapi. Metode yang digunakan dalam penulisan artikel ini dengan melakukan kajian pustaka berbagai buku teks, jurnal baik internasional dan nasional serta analisis konten dari peraturan perUndang-Undangan yang menyangkut tentang ketenagakerjaan dan disabilitas. Data dalam artikel ini dikumpulkan melalui studi pustaka dan observasi. Dasar analisis yang digunakan adalah analisis konten dari regulasi ketenagakerjaan dan hak disabilitas yang telah diberlakukan di Indonesia pada umumnya dan Kota Surakarta pada khususnya. Temuan yang ada menyebutkan bahwa peraturan perUndang-Undangan yang ada telah memberikan peluang kesetaraan bagi kaum disabilitas memasuki dunia kerja, akan tetapi tantangan sosial masih menjadi penghambat kesetaraan disabilitas dalam kesempatan kerja. Implikasinya penyedia lapangan kerja harus memenuhi hak kaum disabilitas dalam kuota kerja yang telah diatur dalam perUndang-Undangan.</p><strong>Kata kunci: disabilitas, diversitas, kesempatan kerja, manajemen sumber daya manusia</strong>
DAFTAR ISI
Authors: Jurnal Administrasi Publik Spirit Publik: 
Published: April 2021

<strong><span style="font-size: small;">Spirit Publik : Jurnal Administrasi Publik</span></strong><span>diterbitkan oleh Program Studi Ilmu Administrasi Negara Fakultas Ilmu Sosial dan Politik Universitas Sebelas Maret (UNS). Jurnal ini menyajikan hasil penelitian dan artikel dalam lingkup kajian kebijakan dan manajemen publik. </span><strong>Spirit Publik : Jurnal Administrasi Publik</strong><span> terbit 2 (dua) edisi dalam satu tahun pada Edisi April dan Oktober. Jurnal telah memiliki e-issn 2580-3875 dan p-issn 1907-0489. </span>
Elementos Marcantes da Prestação de Contas Voluntária das 100 Melhores ONGS do Brasil
Authors: Sales Jaqueline Cavalari , Portulhak Henrique , Pacheco Vicente 
Published: April 2021

A investigação identificou os elementos presentes na prestação de contas voluntária das “100 Melhores ONGs do Brasil” de 2018 de acordo com o Instituto Doar e Rede Filantropia. A análise considerou cinco dimensões: completude, acessibilidade, transparência, divulgação total e relevância. Fez-se uso da estatística descritiva, com ordenação por quartis conforme o porte das organizações, usando como critério de agrupamento a receita total anual. Com base em um checklist composto por 73 itens, os resultados indicaram que as ONGs utilizam seus websites principalmente para fornecer informações gerais e com o intuito de promover suas ações (relevância), evidenciando menor participação das demais dimensões, achado coerente aos estudos anteriores. Também em consonância à literatura, evidenciou-se que ONGs de maior porte apresentaram maior accountability, excetuando-se a dimensão transparência. O estudo contribui para que ONGs tenham subsídios para melhorar sua prestação de contas, aumentando a confiança de stakeholders e contribuindo para sua sustentabilidade financeira.
Transient Modeling of Plunger Lift for Gas Well Deliquification
Authors: Zhao Qingqi , Zhu Jianjun , Cao Guangqiang , Zhu Haiwen , Zhang Hong-Quan 
Published: April 2021

SummaryAs an economical and efficient artificial lift method, plunger lift can be used to unload the accumulated liquids from the bottom of gas wells, which helps lower the bottomhole pressure, resulting in higher gas production rate. However, the transient flow behavior of the plunger-lift-aided production system is still not well understood due to the lack of a reliable and accurate prediction model. In this study, a transient mechanistic model is developed to simulate the comprehensive dynamic process of a plunger-lift system that is cyclically paced by a surface control valve.Starting from the Gasbarri and Wiggins (2001) dynamic plunger-lift model, four stages in the cyclic movement of a plunger can be identified and calculated using a set of specific governing equations. Considering the gas flows with a plunger in the tubing, the model can calculate the instant velocities of the plunger during its rising and falling movement. The classical inflow performance relationship (IPR) is employed as the reservoir model to obtain the fluid flow rates from the reservoir to the wellbore. The proposed new model can capture the essential parameters of plunger-lift cycles, including plunger velocity/acceleration, tubing/casing pressure, production rates, etc. Compared to previous models, the predicted rising and falling speeds of the plunger are improved. The hydrocarbon mixture properties in the gas well are computed by a compositional model in this study, which provides more accurate and reasonable predictions of tubing and casing pressure.Several parametric studies are presented in the paper. These studies will help to understand the influence of different parameters on the process of plunger lift. An appropriate combination of casing and tubing pressure should be taken into consideration. A reservoir coefficient term is introduced and defined. A larger reservoir coefficient will improve the ultimate profitability of the well by increasing the production rate at the beginning and accelerate the depletion of gas wells. If the gas/liquid ratio (GLR) is too low, liquid loading may be triggered. The parametric study shows that an adequate GLR is necessary for reliable plunger-lift performance.
Protocol for subcellular targeted microthermal protein damage in cells cultivated on plasmonic nanosilver-modified surfaces
Authors: Mistrik Martin , Skrott Zdenek , Muller Petr , Panacek Ales , Hochvaldova Lucie , Chroma Katarina , Buchtova Tereza , Vandova Veronika , Kvitek Libor , Bartek Jiri 
Published: April 2021

Abstract
Despite proteotoxic stress and heat shock are implicated in diverse pathologies, currently no methodology to inflict defined, subcellular thermal damage exists. Here, we present a protocol for such a single-cell method compatible with laser-scanning microscopes, adopting the plasmon resonance principle. The method is based on modified microscopic cell culture plates, pre-coated by a layer of anisotropic silver NPs allowing excitation through targeted irradiation by conventional lasers used in the laser scanning microscopes and allowing controllable heating. Dose-defined heat causes protein damage in subcellular compartments, rapid heat-shock chaperones recruitment and stress signalling, thereby allowing unprecedented spatiotemporal analysis of thermal damage with broad applicability in biomedicine.
Investigation on the removal characteristics of single-point cutting high-volume fraction SiCp/Al composites
Authors: Bao Yongjie , Zhang Xu , Lu Shouxiang , Zhang Hongzhe 
Published: April 2021

Abstract
SiC reinforced aluminum matrix composites (SiCp/Al composites) are typical difficult-to-machine material, and the irregular SiC particles diffused in SiCp/Al composites make the surface quality worse. In this paper, a single-point cutting investigations with finite element simulation were conducted for 65% SiCp/Al composites and aluminum alloy. The surface morphology characteristics of SiCp/Al composites, which mainly include breaking, part breaking, pulling out, protruding, al tearing, and interface debonding, are different from those of aluminum alloy materials. The high-volume SiC particles lower the surface quality and profile dimensional accuracy of SiCp/Al composites. There are thin and discrete layers covered on the machined surface.
OXM-104, a potential candidate for the treatment of obesity, NASH and type 2 diabetes
Authors: Kayed Ashref , Melander Simone , Andreassen Kim , Karsdal Morten , Henriksen Kim 
Published: April 2021

Abstract
Obesity-related metabolic disorders, including non-alcoholic fatty liver disease and its more progressive form non-alcoholic steatohepatitis, are causing an increased health burden, especially due to the lack of approved treatment options. Using preclinical models of NASH, obesity, and type 2 diabetes, we investigated the effects of a long-acting glucagon-like peptide-1(GLP-1) and glucagon (GCG) receptor agonist OXM-104 head to head with once-daily GLP-1/GCG receptor agonist cotadutide and once-weekly GLP-1 receptor agonist semaglutide. OXM-104, cotadutide, and semaglutide elicited marked reductions in body weight and improved glucose control. In contrast, hepatoprotective effects, i.e., reductions in steatosis and fibrosis, as well as liver fibrosis biomarkers, were more prominent with OXM-104 and cotadutide than effects seen with semaglutide. This is demonstrated by improved NAFLD activity score (NAS) by OXM-104 and cotadutide which underlines the importance of the GCG receptor. Thus, these results underline the potential of OXM-104 as a promising therapeutic option for the resolution of NASH, but also as a therapeutic option for type 2 diabetes and obesity.
Postural Analysis: Description of a Dedicated System
Authors: Palandri Sergio 
Published: April 2021

Abstract
Postural analysis is a fundamental tool for evaluating the neuromusculoskeletal structure of a subject. Although it is an important tool, a unique formal analysis process has not yet been determined. The aim of this work is to propose a postural analysis protocol that can be used for both initial investigations and ongoing monitoring of the effects of therapeutic treatment in the field. A second aim of this work, equally important in the opinion of the author, is to promote discussion with other practitioners so as to make continuous improvements in the proposed protocol to provide a tool that can serve the needs of specialists even more efficiently. The proposed system consists of four subsystems: medical history data, photographic references, overall observations, and tests. Even though the initial results are encouraging, additional use of the described analysis system is considered essential to improve the technique and the skills of the operator. In this light, specific requests and observations from other professionals are essential, and obtaining these requests and observations is one of the purposes of the present article, as initially declared. The proposed postural analysis system represents a good balance of various, often opposing needs, being easily completed and reasonably fast and repeatable, making it possible to compare time series data.