bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical study on a rotational hydraulic damper with variable damping coefficient
Authors: Zhao Huiyong , Wang Baohua , Chen Genfu 
Published: November 2021

AbstractThe rotational hydraulic damper has advantages in the design and control of rotational machines. This paper presents a novel hydraulic rotational damper with the characteristic of adjusting the damping coefficient. It is composed of a shell, a gap, a rotor shaft, sliding vanes, a valve, and a motor, just like a combination of a sliding pump system and a valve driven by a motor. A new cam ring slot designed to guide the radial motion of sliding vanes could reduce friction resistance force, which will also benefit the design of the sliding pump. The damping coefficient model of this damper is established based on dynamic analysis. Series of numerical simulations validate the impact of factors on the damping coefficient. Frictional resistances have little influence on the damping coefficient during most conditions. The total coefficient is positively correlative with the angular velocity and the valve angle. Therefore, changing the valve angle according to the rotor shaft’s angular speed could adjust the damping coefficient.
An inverse method for mechanical characterization of heterogeneous diseased arteries using intravascular imaging
Authors: Narayanan Bharath , Olender Max L. , Marlevi David , Edelman Elazer R. , Nezami Farhad R. 
Published: November 2021

AbstractThe increasing prevalence of finite element (FE) simulations in the study of atherosclerosis has spawned numerous inverse FE methods for the mechanical characterization of diseased tissue in vivo. Current approaches are however limited to either homogenized or simplified material representations. This paper presents a novel method to account for tissue heterogeneity and material nonlinearity in the recovery of constitutive behavior using imaging data acquired at differing intravascular pressures by incorporating interfaces between various intra-plaque tissue types into the objective function definition. Method verification was performed in silico by recovering assigned material parameters from a pair of vessel geometries: one derived from coronary optical coherence tomography (OCT); one generated from in silico-based simulation. In repeated tests, the method consistently recovered 4 linear elastic (0.1 ± 0.1% error) and 8 nonlinear hyperelastic (3.3 ± 3.0% error) material parameters. Method robustness was also highlighted in noise sensitivity analysis, where linear elastic parameters were recovered with average errors of 1.3 ± 1.6% and 8.3 ± 10.5%, at 5% and 20% noise, respectively. Reproducibility was substantiated through the recovery of 9 material parameters in two more models, with mean errors of 3.0 ± 4.7%. The results highlight the potential of this new approach, enabling high-fidelity material parameter recovery for use in complex cardiovascular computational studies.
Structural modification of fentanyls for their retrospective identification by gas chromatographic analysis using chloroformate chemistry
Authors: Valdez Carlos A. , Leif Roald N. , Sanner Robert D. , Corzett Todd H. , Dreyer Mark L. , Mason Katelyn E. 
Published: November 2021

AbstractThe one-step breakdown and derivatization of a panel of nine fentanyls to yield uniquely tagged products that can be detected by Electron Ionization Gas Chromatography-Mass Spectrometry (EI-GC-MS) is presented. The method involves the treatment of the synthetic opioids with 2,2,2-trichloroethoxycarbonyl chloride (TrocCl) at 60 °C for 3 h in dichloromethane and furnishes two products from one fentanyl molecule that can be used to retrospectively identify the original opioid. Parameters that were studied and fully optimized for the method included temperature, solvent, nature of scavenging base and reaction time. One of the two resulting products from the reaction bears the trichloroethoxycarbonyl (Troc) tag attached to the norfentanyl portion of the original opioid and greatly aids in the opioid detection and identification process. The methodology has been applied to the chemical modification of a panel of nine fentanyls and in all cases the molecular ion peak for the Troc-norfentanyl product bearing the distinctive trichloroethyl isotopic signature can be clearly observed. The method’s LLOD was determined to be 10 ng/mL while its LLOQ was found to be 20 ng/mL. This methodology represents the first application of chloroformates in the chemical modification of this class of synthetic opioids that are notoriously inert to common derivatization strategies available for GC–MS analysis.
The MHD Newtonian hybrid nanofluid flow and mass transfer analysis due to super-linear stretching sheet embedded in porous medium
Authors: Mahabaleshwar U. S. , Anusha T. , Hatami M. 
Published: November 2021

AbstractThe steady magnetohydrodynamics (MHD) incompressible hybrid nanofluid flow and mass transfer due to porous stretching surface with quadratic velocity is investigated in the presence of mass transpiration and chemical reaction. The basic laminar boundary layer equations for momentum and mass transfer, which are non-linear partial differential equations, are converted into non-linear ordinary differential equations by means of similarity transformation. The mass equation in the presence of chemical reaction is a differential equation with variable coefficients, which is transformed to a confluent hypergeometric differential equation. The mass transfer is analyzed for two different boundary conditions of concentration field that are prescribed surface concentration (PSC) and prescribed mass flux (PMF). The asymptotic solution of concentration filed for large Schmidt number is analyzed using Wentzel-Kramer-Brillouin (WKB) method. The parameters influence the flow are suction/injection, superlinear stretching parameter, porosity, magnetic parameter, hybrid nanofluid terms, Brinkman ratio and the effect of these are analysed using graphs.
Further insight into the global variability of the OCA2-HERC2 locus for human pigmentation from multiallelic markers
Authors: Suarez Philippe , Baumer Karine , Hall Diana 
Published: November 2021

AbstractThe OCA2-HERC2 locus is responsible for the greatest proportion of eye color variation in humans. Numerous studies extensively described both functional SNPs and associated patterns of variation over this region. The goal of our study is to examine how these haplotype structures and allelic associations vary when highly variable markers such as microsatellites are used. Eleven microsatellites spanning 357 Kb of OCA2-HERC2 genes are analyzed in 3029 individuals from worldwide populations. We found that several markers display large differences in allele frequency (10% to 35% difference) among Europeans, East Asians and Africans. In Europe, the alleles showing increased frequency can also discriminate individuals with (IrisPlex) predicted blue and brown eyes. Distinct haplotypes are identified around the variants C and T of the functional SNP rs12913832 (associated to blue eyes), with linkage disequilibrium r2 values significant up to 237 Kb. The haplotype carrying the allele rs12913832 C has high frequency (76%) in blue eye predicted individuals (30% in brown eye predicted individuals), while the haplotype associated to the allele rs12913832 T is restricted to brown eye predicted individuals. Finally, homozygosity values reach levels of 91% near rs12913832. Odds ratios show values of 4.2, 7.4 and 10.4 for four markers around rs12913832 and 7.1 for their core haplotype. Hence, this study provides an example on the informativeness of multiallelic markers that, despite their current limited potential contribution to forensic eye color prediction, supports the use of microsatellites for identifying causing variants showing similar genetic features and history.
Grain size dependent high-pressure elastic properties of ultrafine micro/nanocrystalline grossular
Authors: Zhang Jin S. , Irifune T. , Hao M. , Zhang D. , Hu Y. , Tkachev S. , Dera P. , Chen J. , Jiang Ying-Bing , Brearley Adrian J. , Bass J. D. , Prakapenka V. 
Published: November 2021

AbstractWe have performed sound velocity and unit cell volume measurements of three synthetic, ultrafine micro/nanocrystalline grossular samples up to 50 GPa using Brillouin spectroscopy and synchrotron X-ray diffraction. The samples are characterized by average grain sizes of 90 nm, 93 nm and 179 nm (hereinafter referred to as samples Gr90, Gr93, and Gr179, respectively). The experimentally determined sound velocities and elastic properties of Gr179 sample are comparable with previous measurements, but slightly higher than those of Gr90 and Gr93 under ambient conditions. However, the differences diminish with increasing pressure, and the velocity crossover eventually takes place at approximately 20–30 GPa. The X-ray diffraction peaks of the ultrafine micro/nanocrystalline grossular samples significantly broaden between 15–40 GPa, especially for Gr179. The velocity or elasticity crossover observed at pressures over 30 GPa might be explained by different grain size reduction and/or inhomogeneous strain within the individual grains for the three grossular samples, which is supported by both the pressure-induced peak broadening observed in the X-ray diffraction experiments and transmission electron microscopy observations. The elastic behavior of ultrafine micro/nanocrystalline silicates, in this case, grossular, is both grain size and pressure dependent.
Annual body mass index gain and risk of hypertensive disorders of pregnancy in a subsequent pregnancy
Authors: Tano Sho , Kotani Tomomi , Ushida Takafumi , Yoshihara Masato , Imai Kenji , Nakano-Kobayashi Tomoko , Moriyama Yoshinori , Iitani Yukako , Kinoshita Fumie , Yoshida Shigeru , Yamashita Mamoru , Kishigami Yasuyuki , Oguchi Hidenori , Kajiyama Hiroaki 
Published: November 2021

AbstractWeight gain during interpregnancy period is related to hypertensive disorders of pregnancy (HDP). However, in interpregnancy care/counseling, the unpredictability of the timing of the next conception and the difficulties in preventing age-related body weight gain must be considered while setting weight management goals. Therefore, we suggest considering the annual change in the body mass index (BMI). This study aimed to clarify the association between annual BMI changes during the interpregnancy period and HDP risk in subsequent pregnancies. A multicenter retrospective study of data from 2009 to 2019 examined the adjusted odds ratio (aOR) of HDP in subsequent pregnancies. The aORs in several annual BMI change categories were also calculated in the subgroups classified by HDP occurrence in the index pregnancy. This study included 1,746 pregnant women. A history of HDP (aOR, 16.76; 95% confidence interval [CI], 9.62 − 29.22), and annual BMI gain (aOR, 2.30; 95% CI, 1.76 − 3.01) were independent risk factors for HDP in subsequent pregnancies. An annual BMI increase of ≥ 1.0 kg/m2/year was related to HDP development in subsequent pregnancies for women without a history of HDP. This study provides data as a basis for interpregnancy care/counseling, but further research is necessary to validate our findings and confirm this relationship.
Sound level context modulates neural activity in the human brainstem
Authors: Herrmann Björn , Yasmin Sonia , Araz Kurdo , Purcell David W. , Johnsrude Ingrid S. 
Published: November 2021

AbstractOptimal perception requires adaptation to sounds in the environment. Adaptation involves representing the acoustic stimulation history in neural response patterns, for example, by altering response magnitude or latency as sound-level context changes. Neurons in the auditory brainstem of rodents are sensitive to acoustic stimulation history and sound-level context (often referred to as sensitivity to stimulus statistics), but the degree to which the human brainstem exhibits such neural adaptation is unclear. In six electroencephalography experiments with over 125 participants, we demonstrate that the response latency of the human brainstem is sensitive to the history of acoustic stimulation over a few tens of milliseconds. We further show that human brainstem responses adapt to sound-level context in, at least, the last 44 ms, but that neural sensitivity to sound-level context decreases when the time window over which acoustic stimuli need to be integrated becomes wider. Our study thus provides evidence of adaptation to sound-level context in the human brainstem and of the timescale over which sound-level information affects neural responses to sound. The research delivers an important link to studies on neural adaptation in non-human animals.
The response of potato tuber yield, nitrogen uptake, soil nitrate nitrogen to different nitrogen rates in red soil
Authors: Liu Kailou , Du Jiangxue , Zhong Yijun , Shen Zhe , Yu Xichu 
Published: November 2021

AbstractNutrient-deficient red soil found in the southern region of China is increasingly being used for potato crops to meet the demand for this staple food. The application of nitrogen fertilizer is necessary to support the production of higher tuber yields; however, the links between nitrate nitrogen and the nitrogen balance in red soil are unknown. A field experiment was conducted in Jiangxi Province in 2017 and 2018 to determine the effects of different nitrogen application rates, 0 kg ha−1 (N0), 60 kg ha−1 (N60), 120 kg ha−1 (N120), 150 kg ha−1 (N150), 180 kg ha−1 (N180), 210 kg ha−1 (N210), and 240 kg ha−1 (N240, the highest rate used by local farmers), on potatoes growing in red soil. Data on tuber yield, crop nitrogen uptake, and the apparent nitrogen balance from the different treatments were collected when potatoes were harvested. Additionally, the content and stock of nitrate nitrogen at different soil depths were also measured. Nitrogen fertilization increased tuber yield but not significantly at application rates higher than 150 kg ha−1. We estimated that the threshold rates of nitrogen fertilizer application were 191 kg ha−1 in 2017 and 227 kg ha−1 in 2018, where the respective tuber yields were 19.7 and 20.4 t ha−1. Nitrogen uptake in potato in all nitrogen fertilization treatments was greater than that in N0 by 61.2–237% and 76.4–284% in 2017 and 2018, respectively. The apparent nitrogen surplus (the amount of nitrogen remaining from any nitrogen input minus nitrogen uptake) increased with increasing nitrogen application rates. The nitrate nitrogen stock at a soil depth of 0–60 cm was higher in the 210 and 240 kg ha−1 nitrogen rate treatments than in the other treatments. Moreover, double linear equations indicated that greater levels of nitrogen surplus increased the nitrate nitrogen content and stock in soils at 0–60 cm depths. Therefore, we estimate that the highest tuber yields of potato can be attained when 191–227 kg ha−1 nitrogen fertilizer is applied to red soil. Thus, the risk of nitrate nitrogen leaching from red soil increases exponentially when the apparent nitrogen balance rises above 94.3–100 kg ha−1.
Understanding Clinician Perspectives and Actions to Address Caregiver Burden in Caregivers of Adults
Authors: Chen Crystal , Shune Samantha , Namasivayam-MacDonald Ashwini 
Published: November 2021

Purpose:
The purpose of this study was to determine how speech-language pathologists (SLPs) perceive and address caregiver burden.

Method:
A 29-question survey was distributed virtually via relevant Facebook pages and professional associations. Ninety-three responses from English-speaking SLPs working with adults in the United States or Canada were analyzed descriptively. Other analyses included one-way analysis of variance and chi-square tests to assess relationships between years of experiences, primary work setting, and other relevant variables, as well as a thematic analysis of one free-text response detailing how respondents defined caregiver burden.

Results:
Respondents associated caregiver burden with physical, psychological, financial, and social strain, loss of personal time, and the COVID-19 pandemic. The most described theme (80%) was physical strain. Almost all respondents (92%) believed that caregiver burden is a prominent issue and reported using strategies such as education and training to reduce burden. Most respondents (86%) would consider adopting a standardized tool to identify caregiver burden. Common barriers to addressing caregiver burden were lack of tools, time, and expertise. Additionally, less than half of respondents reported being confident in their ability to appropriately refer caregivers for support (45%).

Conclusions:
Most SLPs interacted with caregivers and used strategies such as education and training within their areas of expertise to try and address caregiver burden. Further research into the resources SLPs need to address caregiver burden is required. This study provides a preliminary understanding of current SLP perspectives and the strategies currently used to address caregiver burden in the United States and Canada.
Noise figure and input intercept point's errors in an AGC‐less microwatt ultrawideband system (limiter and low noise amplifier)
Authors: Shahrabadi Shahab 
Published: November 2021

AbstractThe goal is to illustrate new errors about using the figures‐of‐merit NF and IIP, by investigating an AGC‐less microwatt ultrawideband ‐boosted CMOS RF system with noise/distortion cancellation. The system composed of limiter and LNA is designed for 0.3–10.7 GHz at 1.8 V. Thanks to the limiter, the impact of noises and distortions is cancelled and the LNA acts linear without any saturation or block, as well as, it becomes AGC‐less. Additionally, achievements prove that NF and IIP sometimes can be accompanied by error, hence engineers must always consider all aspects of a system together during their evaluations. Although this work is not experimental, it applies different methods such as “Regenerating”, “Comparing Calculations with Simulations” and “Monte Carlo” to demonstrate the reliability of achievements for applying in a SAW‐less RFIC.
A frequency mapping method for locating functional units inside ICs based on coaxial microscope
Authors: Liu Pengcheng , Han Jianwei , Ma Yingqi , Zhang Feng , Wu Zongguo , Zhu Xiang , Cui Yixin 
Published: November 2021

AbstractLocating the physical position of functional units of the chip is a mandatory first step in various fields of applications, such as reverse engineering and hardware security. This paper presents a frequency mapping method based on the coaxial microscope to locate functional units inside ICs. A visible light camera is employed to focus the laser on the active region of the device under test based on the principle that the laser is strongly reflected at the metal in the active region. The target circuit modulates the laser at its operating frequency and the position of the target circuit could be accurately located by analyzing the frequency characteristics of the reflected laser. The results of transceiver chip localization indicate that the target circuit on the chip can be precisely located by this method without any additional processing of the chip. The coaxial microscopy design provides a good spot quality and signal‐to‐noise ratio, meanwhile, locating areas of the chip with operating currents down to 10−10 A, compared with that of photonic emission analysis can only achieve the sensitivity of 5 × 10−4 A. The sensitivity of the frequency mapping method is much better than that of Photonic Emission Analysis.
Automotive interference statistics and their effect on radar detector
Authors: Pirkani Anum , Norouzian Fatemeh , Hoare Edward , Cherniakov Mikhail , Gashinova Marina 
Published: November 2021

AbstractMillimetre‐wave frequency‐modulated continuous wave (FMCW) radars are at present widely deployed in the autonomous vehicles. The growing usage of such sensors, as a vital part of a robust future autonomous sensing system, sees the potential for significant increase in mutual interference and adverse effects on sensor operation. Effective target detection in the background of interference requires knowledge of the interference statistics. In the case that such statistics are found to be similar to that of additive white Gaussian noise (AWGN), then classical well‐established detection techniques can be applied. Conversely, if statistics are found to be different, traditional techniques (matched filtering) will not be optimal. Here, a statistical analysis of mutual interference within an FMCW victim radar is presented. The majority of cases show a low correlation between the interference pulses received at the victim radar, with close to a Gaussian distribution. Some specific cases show a high correlation between the interference pulses in the victim radar chirps with a sinusoidal‐like distribution, which degrades the victim radar’s detection performance. The presented analysis is validated by experimental data for various interference cases.
Design of an acoustic sensor for fission gas release characterization devoted to JHR environment measurements
Authors: Baudry F. , Rosenkrantz E. , Combette P. , Fourmentel D. , Destouches C. , Ferrandis J.Y. 
Published: November 2021

Among numerous research projects devoted to the improvement of the nuclear fuel behaviour knowledge, the development of advanced instrumentation for in-pile experiments in Material Testing Reactor is of great interest. In the frame of JHR reactor, new requirements have arisen creating new constraints.
An acoustic method was tested with success during a first experiment called REMORA 3 in 2010 and 2011, and the results were used to differentiate helium and fission gas release kinetics under transient operating conditions. This experiment was leading at OSIRIS reactor (CEA Saclay, France). The maximal temperature during the irradiation test was about 150 °C. [1], [2]. We have developed thick film transducers produced by screen-printing process. They offered a wide range of possible application for the development of acoustic sensors and piezoelectric structure for harsh temperature environment measurements [3]. We proposed a screen-printed modified Bismuth Titanate piezoelectric element on alumina substrate allowing acoustic measurements [4] for JHR environment. In this paper we will focus on the mechanical design of the new sensor. This acoustic sensor is composed of an acoustic element for generation and detection of acoustic waves propagating into a cavity filled with gaz. We will detail the choice of piezoelectric materials, the thickness of the different layers, the cavity shapes, the electrical connections, the means of assembly of the different parts. Theoretical and experimental results will be given. All that point will be discussed in terms of acoustic sensor sensitivity versus dimensional constraints, in the case of a high temperature range working.