bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rola wymiany towarowej ze wschodnimi sąsiadami Polski w gospodarce lokalnej
Authors: Komornicki Tomasz 
Published: February 2021

The purpose of this article is to investigate the current role of trade with Russia, Ukraine and Belarus in the local economy of East Poland. It is assumed that the importance of trade with neighbouring countries can be expressed through: (a) export of goods that are made in a given spatial unit to the markets of adjacent countries; (b) providing service for the needs of transit traffic, including in particular the freight traffic generated by Polish foreign trade; (c) small-scale, unregistered trade along the border areas. The research study focuses mainly on the four borderland voivodships. The analysis shows that after the years 2003/2004 in East Poland there has been a declining importance of the borderland location as a stimulus factor which contributes to intensive interactions with the neighbouring countries. The role of trade of goods with Belarus, Russia and Ukraine in the economy of borderland regions is becoming ever less important and ever more spatially selective. The advantages derived from trans-border traffic services are increasingly evident in the border crossings leading into Lithuania and Ukraine, with a rather declining significance of those crossings with Belarus. The advantages linked to peddling small items are mainly concentrated in the border gminas (communes) that are located in the close neighbourhood of the border crossings.At the same time, however, risks related to trade of goods are playing ever more important role, since excessive concentration of exporters to the markets of the neighbouring countries may pose a threat of “importing” the crisis. Intensive transit of goods generates considerable external costs, while trans-border illegal trading is increasingly becoming an unfair trade for local entrepreneurs.
Utilização da tecnologia CAD/CAM em clínicas odontológicas: revisão de literatura
Authors: Palma Flávio Augusto de Moraes , Martim Letícia , De Amorim João Vitor Oliveira , Abreu Gustavo Baruc Andrade , De Almeida Gustavo Henrique Santos , De Souza Victor Arthur Rodrigues , Feitosa Marcus Vinícius Simões , Barbosa Ezequiel Santos , Góis Izabela Lima , Nahsan Flavia Pardo Salata 
Published: February 2021

Objetivo: Identificar a aplicabilidade do uso do CAD/CAM em clínicas odontológicas, assim como os benefícios da utilização. Métodos: trata de estudo é uma revisão de literatura de pesquisa qualitativa, onde realizou-se quatro etapas onde as mesmas foram divididas das seguintes formas: (1) Seleção das palavras chaves da pesquisa; (2) Busca de artigos em bases de dados e Portais eletrônicos; (3) Selecionar estudos com base em critério de inclusão/exclusão; (4) Leitura dos artigos na integra. Resultados: de acordo a pesquisa, foram selecionados 21 artigos, divididos por autores, título, ano e periódicos. Diante dos artigos encontrados, os autores relatam a eficiência clínica, pois o sistema CAD/CAM pode atuar em diversos procedimentos clínicos, obtendo um ótimo resultado no tempo de trabalho, qualidade no procedimento e satisfação do paciente, por ser um procedimento rápido e menos invasivo. Considerações finais: Considera que os tratamentos propostos podem variar, desde a produção de coroas unitárias, facetas, prótese sobre implante, implantes dentários e até a realização de guias cirúrgicos e benéficos gerados pelo CAD/CAM podem ser: ganho de eficiência e tempo de trabalho; pode aumentar a qualidade e precisão do seu trabalho e o tempo de espera do paciente ao seu tratamento.
The Effectiveness of Gelfoam as the Sole and Primary Embolization Agent in the Management of Hemoptysis: A Retrospective Study from a Tertiary Care Center
Authors: Ruge Abhinandan , Kumar Nidhi , Menezes Clyde 
Published: February 2021

Objectives:
The objective of this study was to evaluate the role of Gelfoam as an effective embolizing agent in patients with hemoptysis presenting to a tertiary care center in developing nations.

Material and Methods:
A retrospective analysis of data from 30 patients treated by Interventional radiologist at St. John’s Medical College, Bangalore, India, was performed. The study included 22 males (73.3%) and 8 (26.65%) female patients. Gelfoam was used as the sole embolizing agent and arteries with features of abnormal blush and hypertrophy were targeted. Analysis of the etiology, immediate, and short-term outcome and complications, when present, was performed. The median follow-up period was 45 days following an embolization procedure at this center.

Results:
A high short-term efficacy was noted following embolization procedures with Gelfoam as the sole agent. Twenty-eight out of 30 procedures were deemed successful, and post-tubercular changes were noted to be the cause for hemoptysis in 23 patients. The high short-term efficacy (93.3%), evidenced by a complete stoppage of hemoptysis, along with a relatively low rate of complications (spinal cord ischemia in only 2.3%), strengthens the position of Gelfoam as the sole embolizing agent in a resource-limited setting.

Conclusion:
In an economically constrained setting, Gelfoam proves to be a useful first choice single embolization agent, while polyvinyl alcohol particles coupled with microcatheter systems remain within reach of only those who can afford them.
IMPLEMENTASI TPACK FRAMEWORK DALAM WORKSHOP SSP PROGRAM PPG UNTUK GURU GEOGRAFI PROFESIONAL
Authors: Ningsih Mega Prani 
Published: February 2021

Program PPG merupakan pendidikan untuk mencetak guru yang kompeten dan professional. Program PPG SM 3T pertama kali dilaksanakan oleh Universitas Negeri Malang (UM) dan Universitas Negeri Surabaya (Unesa). Workshop SSP sebagai bagian Program PPG dalam model kolaboratif di UM dan Unesa belum secara menyeluruh menerapkan kerangka TPACK. Hal ini berdampak pada lulusan yang belum terlatih membuat media pembelajaran berbasis teknologi digital. Penelitian ini merupakan penelitian deskriptif melalui pendekatan kualitatif dengan desain studi kasus di UM dan Unesa pada Prodi Pendidikan Geografi. Data penelitian terdiri dari data primer berupa informan kunci dan data sekunder berupa dokumen Program PPG. Teknik pengumpulan data melalui wawancara mendalam dan dokumentasi. Analisis data menggunakan model interaksi Miles dan Huberman. Hasil penelitian ini menunjukkan bahwa pembelajaran melalui blended learning menjadi salah satu alternatif yang dapat diterapkan untuk mengolaborasikan pembelajaran konvensional dan modern berbasis teknologi digital. Proses belajar dapat dilakukan secara offline dan online. Oleh karena itu, calon guru perlu mempelajari, menciptakan, dan menggunakan berbagai teknologi digital yang ada dalam pembelajaran blended learning.
POTENSI PERIKANAN AIR TAWAR SEBAGAI DAYA DUKUNG MINAWISATA DI KELURAHAN CIBUNIGEULIS KOTA TASIKMALAYA
Authors: Singkawijaya Elgar Balasa 
Published: February 2021

Kota Tasikmalaya sejak tahun 2001 mengalami pertumbuhan dan perkembangan yang pesat karena didukung dengan berlakunya otonomi daerah. Wilayah Kelurahan Cibunigeulis yang berada di Kecamatan Bungursari merupakan wilayah yang unggul dengan potensi budi daya perikanan air tawar dan juga memiliki nilai potensi untuk digunakan dengan membangun kegiatan minawisata. Adapun tujuan penelitian adalah untuk mengetahui karakteristik sektor perikanan air tawar sebagai daya dukung minawisata dan bentuk kegiatan potensi minawisata. Metode yang digunakan dalam penelitian ini adalah metode deskriptif kuantitatif. Hasil penelitian menunjukkan kegiatan pemeliharaan ikan dari segi lokasi yaitu dengan kondisi fisik dan daya dukung tempat pemeliharan yang ideal seperti kolam, tenaga kerja, pembibitan, pengetahuan dan modal. Dalam proses tahapan dalam mengelola pemeliharaan ikan yang baik dan benar sehingga menghasilkan produk yang baik, diantaranya adalah tahap persiapan kolam, tahap pemupukan, tahap pemijahan, tahap penetasan telur menjadi larva ikan. Setelah itu memasuki tahap pendederan, tahap pembesaran, tahap pemanenan, tahap pengolahan dan tahap pemasaran. Adapun ikan yang di pelihara merupakan komoditas utama untuk kebutuhan konsumsi baik dalam kota dan luar kota. Beberapa produk ikan diantaranya ikan mas, ikan lele, ikan mujair, ikan nila, ikan nilem dan ikan lainnya. Untuk kegiatan dalam skala usaha skala usaha besar, sedang dan kecil. Dari segi luas kolam, sebagian besar pembudi daya memiliki skala usaha besar dengan luas kolam lebih dari 400 m2. Dari segi penggunaan tenaga kerja sebagian besar pembudi daya ikan termasuk dalam skala usaha kecil. Adapun daya dukung untuk kegiatan minawisata diantaranya kegiatan pemancingan, kuliner produk makanan lokal dan pameran ikan.
CHANGING NATURE OF DANCE IN PRESENT SOCIETY
Authors: Malaviya Rekha 
Published: February 2021

The dance is a ritual performance of human expressions. It is a universal art, born with human life. The child cries as soon as he is born, hands and feet, expresses his feelings that he is hungry. The dance originated from these interactive acts which are well known. The dance started with spirituality. Initially the dance was performed in temples for devotion to God. With the changing times, during the Mughal period, it came out of temples and started being in the court of kings. Currently, the meaning of dance has changed further. Today dance has come on stage. The dance artist performs the stage, so that the common people enjoy it to its fullest.
नृत्य मानवीय अभिव्यक्तियों का एक रसमय प्रदर्शन है। यह एक सार्वभौमिक कला है, जिसका जन्म मानव जीवन के साथ हुआ। बालक जन्म लेते ही रोकर, हाथ-पैर मारकर अपनी भावाभिव्यक्ति करता है कि वह भूखा है। इन्हीं आंगिक क्रियाओं से नृत्य की उत्पत्ति हुई जो सर्वविदित है। नृत्य का आरम्भ आध्यात्म से हुआ। प्रारम्भ में नृत्य मंदिरों में ईश्वर की भक्ति के लिये किया जाता था। बदलते समय के साथ ही मुगल काल में यह मंदिरो से निकलकर राजाओं के दरबार में होने लगा। वर्तमान में नृत्य के मायने और बदल गये है। आज नृत्य मंचो पर आ गया है। नृत्य कलाकार मंच प्रदर्शन करता है, जिससे जन सामान्य इसका पूर्णता से आनन्द लेते है।
Pelatihan Manajemen Koperasi Syariah di Desa Kerinjing, Kabupaten Ogan Ilir, Sumatera Selatan
Authors: Hamidi Ichsan , Bashir Abdul , Atiyatna Dirta Pratama , Sukanto Sukanto , Mukhlis Mukhlis 
Published: February 2021

Koperasi Syariah merupakan bagian dari Lembaga keuangan syariah (LKS) yang berlandaskan prinsip syariah dan bertujuan untuk meningkatkan kesejahteraan masyarakat dengan berorientasikan keuntungan dan juga falah. Sehingga bukan hanya satu pihak saja yang mendapatkan keuntungan, akan tetapi kedua belah pihak yang bisa merasakan keuntungan, terutama daerah pedesaan yang masih sangat membutuhkan keberadaan koperasi syariah dalam menunjang kehidupan masyarakat. Dalam kenyataannya masyarakat desa Kerinjing Kecamatan Tanjung Raja Selatan Kabupaten Ogan Ilir Provinsi Sumatera Selatan masih mengalami kesulitan dalam mencari pinjaman yang berlandaskan syariah, sehingga masyarakat terpaksa meminjam ke rentenir yang menerapkan sistem bunga. Maka itu perlu dilakukan pemahaman kepada masyarakat desa kerinjing terkait karakteristik, prinsip, dan tujuan ekonomi Islam melalui pelaksanaan koperasi syariah. Hasil pengabdian menunjukkan bahwa terjadi peningkatan pengetahuan dan pemahaman aparat desa dan masyarakat tentang koperasi syariah dengan melibatkan partisipasi dan kerjasama seluruh aspek masyarakat. Masyarakat desa kerinjing ingin menerapkan dan segera mendirikan koperasi syariah. Melalui peran serta aktif masyarakat desa maupun koperasi syariah yang ada di desa kerinjing maka diharapkan hasilnya bisa berkontribusi terhadap pembangunan perdesaaan itu sendiri.
RUANG LINGKUP ANTROPOLOGI HUKUM
Authors: Rahmawani Rezkia Suci 
Published: February 2021

Antropologi hukum mengkaji suatu budaya yang terjadi pada kelompok masyarakat dan sosiologi hukum lebih menitik beratkan pada pada manusia dan berbagai proses hubungan sosialnya. Adanya antropologi hukum dan sosiologi hukum membuat kehidupan masyarakat menjadi lebih teratur.
Webinar Menangkal Cyberporn Pada Internet dan Android Memanfaatan Add Ons dan Aplikasi Antipornografi Parental Control Di SMA Panca Budi
Authors: Batubara Supina , Wahyuni Sri , Hariyanto Eko , Lubis Akhyar 
Published: February 2021

Penyebaran konten pornografi melalui internet dan telepon seluler sudah sangat mengkawatirkan Pornografi di internet memang telah menjadi sebab industri dengan skala bisnis yang besar. Hingga saat ini pemerintah terlihat kesulitan untuk mengatasi persoalan situs pornografi. Upaya pemblokiran situs-situs pornografi di Indonesia terus dilakukan, namun, situs-situs porno (cyberporn) juga terus tumbuh. Dampak negatif cyberporn telah terbukti sangat mengkawatirkan terutama bagi remaja sebagai generasi muda. Dilakukan survey di Indonesia menunjukkan hasil responden 90 persen dari pelajar SD, SMP, dan SMA sudah mengakses pornografi. Orang tua memiliki tugas untuk melakukan pengawasan atau pengendalian (parental control) dari penggunaan internet bagi anaknya, terlebih lagi saat masa pandemi saat ini penggunaan internet pada perangkat android sudah menjadi kebutuhan primer. Untuk itu kegiatan pengabdian kepada masyarakat ini dilakukan dengan melaksanakan webinar yang dilengkapi dengan diskusi dan tanya jawab langsung oleh narasumber dengan tujuan agar orang tua dan pihak sekolah dapat mengetahu dampak negative paparan pornografi dan mengetahui cara memberantas bagaimana cara memblokir, menangkal, juga membasmi cyberporn di internet dan android. Hasil pelaksanaan webinar tim pengabdian dapat merangkum bahwa orang tua, guru dan pihak sekolah mampu melakukan penangkalan cyberporn sesuai dengan hasil yang diharapkan hal ini terlihat pada post-test setelah kegiatan webinar.
Pelatihan Aplikasi Perkantoran Untuk Meningkatan Kualitas SDM Perangkat Desa Karangmangu
Authors: Warjiyono Warjiyono , Suryanti Ery , Rousyati Rousyati , Fatmawati Fanny , Tazali Imam , Lisnawati Lisnawati , Rosihyana Rosihyana 
Published: February 2021

Desa merupakan kesatuan masyarakat hukum yang memiliki batas-batas wilayah yang berwenang untuk mengatur dan mengurus kepentingan masyarakat setempat, Desa dipimpin oleh Lurah atau Kepala Desa yang dibantu oleh perangkat desa untuk menjalankan pelayanan kepada masyarakat seperti pembuatan surat keterangan dan surat penganta lainnya. Perangkat Desa Karangmangu Kecamatan Tarub Kabupaten Tegal rata-rata masih belum bisa mengoperasikan microsoft word dan excel, sehingga layanan kepada masyarakat waktunya menjadi lama dan kurang efektif. Padahal beberapa unit komputer telah tersedia, namun minimnya perangkat desa yang bisa mengoperasikan microsoft word dan excel, komputer tersebut tidak digunakan maksimal. Perlunya pelatihan Microsoft Word dan Microsoft Excel 2013 untuk meningkatkan kualitas SDM perangkat Desa Karangmangu Kecamatan Tarub Kabupaten Tegal. Metode pengumpulan data adalah wawancara dan survey. Hasil pelatihan ini menunjukan bahwa pelatihan microsoft word dan excel 2013 mampu meningkatkan skill perangkat Desa Karangmangu Kecamatan Tarub Kabupaten Tegal dalam mengoperasikan microsoft word dan excel 2013. Hal ini dapat membantu kelancaran pekerjaan sehari-hari dan meningkatkan pelayanan administrasi Desa Karangmangu.
The influence of the organization of the educational process on the mental capacity of secondary school students
Authors: Danylenko H. М. , Sotnikova-Meleshkina Zh. V. 
Published: February 2021

Annotation. The modern education system is characterized by the introduction of the latest technologies and educational projects, accompanied by an increase in information and emotional load, which is accompanied by a decrease in the efficiency and quality of work, determined by the level and dynamics of mental performance. The purpose of the study – to determine the impact of the organization of the educational process in primary school on the mental capacity of students in the study of subjects of varying difficulty. The study involved 112 secondary school students, divided into 3 groups depending on the curriculum. With the help of proofreading tests, the level and dynamics of mental performance was determined in a cycle of studying 3 subjects: mathematics, Ukrainian language, history. In parallel, self-assessment of psycho-emotional state was performed according to the method of SAN and pulse measurement. Statistical data processing was performed using one-way analysis of variance and t-test in the software package IBM SPSS Statistics v.20. It was found that the educational program affected the level of mental performance (F=106.7), heart rate (F=25,2) and well-being (F=4,5; p<0,05). Quantitative (382.31±5.46 characters) and qualitative (7.60±0.28 errors) indicators were better in girls (p<0.01). The maximum decrease in the volume and quality of work was determined after the history lesson (respectively by 27.65±7.24 characters and 3.35±0.49 errors; p<0.001). In the dynamics of the study of subjects there was a decrease in mental capacity against the background of a decrease in health to 1.9 points (p<0.05) and an increase in heart rate to 92.13±2.82 beats/min (p<0.001). The study of mathematics according to the experimental educational project was accompanied by the highest percentage of students with the preservation or increase of the level of mental capacity, and according to the traditional program – its decrease in the vast majority of students. When studying the Ukrainian language and history, no significant difference between the types of changes in mental performance under the conditions of implementation of different curricula has been established. Thus, the optimal organization of the educational process, especially in the study of heavy subjects, helps to preserve and restore mental performance and, consequently, reduce signs of fatigue, which guarantees not only a sufficient level of academic success, but also less depletion of functional reserves of the child's body and reducing the risk of school maladjustment.
TINGKAT PARTISIPASI MASYARAKAT PADA KEGIATAN REHAB RUMAH TIDAK LAYAK HUNI DI KOTA TANGERANG
Authors: Maulana Imron , Sunarti S 
Published: February 2021

Kota Tangerang mencoba mengatasi masalah permukiman melalui program “Tangerang Berbenah” guna mempersiapkan kawasan hunian layak huni dengan lingkungan yang ramah dan sehat. Salah satu kegiatan dari program ini adalah rehab rumah tidak layak huni (RTLH) dengan menggunakan pendekatan partisipasi masyarakat, namun permasalahan partisipasi pada setiap daerah memiliki kecenderungan yang berbeda beda. Kegiatan rehab RTLH ini dilakukan di beberapa tempat yaitu Kelurahan Kedaung Baru dan Kelurahan Batu Ceper. Tujuan penelitian ini adalah untuk menganalisis tingkat partisipasi masyarakat pada kegiatan rehab RTLH. Metode penelitian yang digunakan adalah metode kuantitatif dengan teknik analisis kuantitatif deskriptif dan tabulasi silang. Terdapat 40 responden yang kesemuanya adalah penerima manfaat bantuan rehab RTLH di Kota Tangerang pada tahun 2018. Hasil penelitian menunjukkan jika tingkat partisipasi masyarakat pada keseluruhan tahapan di Kota Tangerang tergolong tinggi atau rebellious dimana masyarakat mau bekerjasama secara kooperatif dengan stakeholder lainnya serta mereka mampu mengambil keputusan sendiri dalam menentukan kemauannya.
Development and Validation of Valganciclovir and its Active Metabolite Ganciclovir Determination in Human Plasma by HPLC-MS/MS Method
Authors: Komarov T. N. , Shohin I. E. , Tokareva M. A. , Archakova O. A. , Bogdanova D. S. , Aleshina A. A. , Bagaeva N. S. , Davydanova V. V. 
Published: February 2021

Introduction. Currently, physicochemical methods of quantification are actively used to determine the content of drugs in biological fluids. High-performance liquid chromatography with various detection methods is particularly widespread. One of the most difficult practical tasks is the chromatographic separation of so-called poorly retained compounds – drug substances poorly retained on the chromatographic column. Valganciclovir and Ganciclovir are among such substances. Aim. The aim of this study is to develop a method for valganciclovir and ganciclovir in human plasma by high performance liquid chromatography with tandem mass-spectrometry (HPLC-MS/MS) for pharmacokinetic studies.Materials and methods. Determination of valganciclovir and ganciclovir in plasma by HPLC-MS/MS. The samples were processed by acetonitrile protein precipitation.Results and discussion. This method was validated by next parameters: selectivity, matrix effect, calibration curve, accuracy, precision, recovery, lower limit of quantification, carry-over and stability.Conclusion. The method of the determination of valganciclovir and ganciclovir in human plasma was developed and validated by HPLC-MS/MS. The linearity in plasma sample was achieved in the concentration range of 5.00–1000.00 ng/ml for valganciclovir and 50.00–10000.00 ng/ml for ganciclovir. Method could be applied to valganciclovir and ganciclovir determination in plasma for PK and BE studies.
PD-L1 as a Potential Target in Cancer Therapy (Review)
Authors: Andrusova N. N. , Kolganova M. A. , Aleshina A. V. , Shohin I. E. 
Published: February 2021

Introduction. Cancer is one of the most serious and common diseases with a high level of mortality. Due to this reason the searching of new directions and methods of cancer treatment is becoming more and more important with each passing year. Significant advances in cancer immunotherapy have been reached over the past few decades. Moreover, an inhibition of the interaction between the programmed cell death receptor (PD-1) and its ligand (PD-L1), is sure to be perspective direction of the immuno-oncological therapy development.Text. PD-1/PD-L1 interaction plays a pivotal role in negative regulation of immune system, that protects host’s cells and tissues from the excessive immune response. However, it is also used by tumor cells to avoid the host's immune system. The discovery of this mechanism led to the development of inhibiting PD-1 or PD-L1 agents that enhance anti-tumor immunity. Meanwhile, anti-PD-L1 agents provide less toxicity in comparison with anti-PD-1 agents. FDA currently approved Atesolizumab, Durvalumab, and Avelumab PD-L1 inhibitors for cancer treatment. These agents demonstrated effective response during the clinical trials, however, they are used for a limited number of oncological diseases. In addition, BMS-936559 is a promising agent that had passed the first stage of the clinical trials. Nevertheless, immunotherapy involving PD-L1 inhibitors is closely related to a vast number of severe side effects including immune-mediated effects caused by the inhibition of PD-L1 ligands located on healthy cells. In these terms, the development of new agents deprived of these disadvantages is the reason for further studies.Conclusion. Immunotherapy in cancer uncovers new perspectives in treatment of refractory to standard therapies forms of cancer. And the development of new and improvement of existing PD-L1 blocking agents are of great importance in fighting against tumoral diseases.