bluuebunny/crossref_metadata_2025_split huggingface dataset:
Soft Computing and Multi-Scal Model Technics to Predict the Early Age Compression Strength of Cement Paste as a Function of Polymer Contents, Water-to-Cement-Ratio, and Curing Ages
Authors: Mohammed Ahmed , Ghafor Kawan , Mahmood Wael , Sarwar Warzer , Burhan Lajan 
Published: November 2021

Abstract
In this study, the effect of two water reducer polymers with smooth and rough surfaces on the compression strength of Ordinary Portland cement (OPC) was investigated. Three different initial ratios between water and cement (w/c) 0.5, 0.6, and 1 were used in this study. The amount of polymer contents varied from 0 to 0.06 % (%wt) for the cement paste with initial w/c of 0.5 and the polymer contents ranged between 0 to 0.16% (%wt) for the cement paste with initial w/c of 0.6 and 1 were investigated. SEM test was conducted to identify the impact of polymers on the behavior of cement paste. The compression strength of OPC cement was increased significantly with increasing the polymer contents. Because of a fiber net (netting) around cement paste particle was developed when the polymers were added to the cement paste which leads to decrease the void between the particles, binding the cement particles, therefore, increased the viscosity and compression strength of the cement rapidly. In this analysis, the hardness of cement paste with polymer contents has been evaluated and modeled using four different model technics. More environmentally sustainable construction, and lower cost than conventional building materials and early age strengths of the cement. To overcome the mentioned matter, this study aims to establish systematic multiscale models to predict the compression strength of cement paste containing polymers and to be used by the construction industry with no theoretical restrictions. For that purpose, a wide data a total of 280 tested cement paste modified with polymers, has been conducted, analyzed, and modeled. Linear, Nonlinear regression, M5P-tree, and Artificial Neural Network (ANN) technical approaches were used for the qualifications. In the modeling process, the most relevant parameters affecting the strength of cement paste, i.e. polymer incorporation ratio (0-0.16% of cement's mass), water-to-cement ratio (0.5-1), and curing ages (1 to 28 days). According to the correlation coefficient (R), mean absolute error and the root means a square error, the compression strength of cement paste can be well predicted in terms of w/c, polymer content, and curing time using four various simulation techniques. Among the used approaches and based on the training data set, the model made based on the Non-linear regression, ANN, and M5P-tree models seem to be the most reliable models. The sensitivity investigation concludes that the polymer content is the most dominating parameter for the prediction of the compression strength of cement paste with this data set.
Uniting The Sun’s Hale Magnetic Cycle and ‘Extended Solar Cycle’ Paradigms
Authors: McIntosh Scott W. , Scherrer Phillip H. , Svalgaard Lief , Leamon Robert J. 
Published: November 2021

Abstract
Through meticulous daily observation of the Sun’s large-scale magnetic field the Wilcox Solar Observatory has catalogued two magnetic (Hale) cycles of solar activity. Those two (∼22-year long) Hale cycles have yielded four (∼11-year long) sunspot cycles-21 through 24. Recent research has highlighted the persistence of the “Extended Solar Cycle” (ESC) and its connection to the fundamental Hale Cycle-albeit through a host of proxies resulting from image analysis of the solar photosphere, chromosphere and corona. This Letter presents, for the first time, a direct mapping between the ESC, the Sun’s toroidal magnetic field evolution of the Hale Cycle. As Sunspot Cycle 25 begins to accelerate its growth, interest in mapping the Hale and Extended cycles could not be higher given potential predictive capability that synoptic scale observations can provide.
The Corporate Innovation in Europe
Authors: Costantiello Alberto , Laureti Lucio , Angelo Leogrande 
Published: November 2021

Abstract
In this article we investigate the political and industrial determinants of firm investment in Research and Development. We use data from the European Innovation Scoreboard of the European Commission for 36 countries in the period 2000-2019. We found that firm investments in Research and Development are positively associated with “Linkages”, “Innovation Index”, “International Co-publications”, “Medium and high-tech product exports”, “Non-R&D innovation expenditure”, “Turnover share large enterprises”, “Human Resources”, “Intellectual Assets”. Firm investments in Research and Development are negatively associated to “Foreign doctorate students”, “Knowledge-intensive services exports”, “Private co-funding of public R&D expenditures”, “Basic-school entrepreneurial education and training (SD)”, “New doctorate graduates”, “Trademark applications”, “Tertiary education” “Design applications”, “Lifelong Learning”, “Foreign-controlled enterprises – share of value added (SD)”, “Total Entrepreneurial Activity (TEA) (SD)”.
The SMEs Innovation in Europe
Authors: Costantiello Alberto , Lucio Laureti , Angelo Leogrande 
Published: November 2021

Abstract
In this article we investigate the determinants of SMEs Innovation in Europe. We use data from the European Innovation Scoreboard of the European Commission in the period 2000-2019 for 36 countries. Data are analyzed through Panel Data with Fixed Effects, Random Effects, Dynamic Panel at 1 Stage and WLS. Results show that the presence of Innovators is positively associated with “Enterprise births”, “Government Procurement of Advanced Technology Products”, “Firm Investments”, “Intellectual Assets”, “Sales Impacts”, “Share High and Medium High-Tech Manufacturing” and negatively associated to “FDI Net Inflows” and “Population Density”.
Spirituality / religiosity of Elderly Front to Health Care: Scope of Review
Authors: Silva Haydêe Cassé da , Moreira Maria Adelaide Silva Paredes , Ferreira Olívia Galvão Lucena , Terra Fábio de Souza , Piagge Carmem Silvia Laureano Dalle , Silva Antonia Leda Oliveira 
Published: November 2021

Abstract
Identify the published evidence on spirituality/religiosity of elderly people facing health care.It is a scope review, based on the recommendations of the JBI Manual for EvidenceSynthesisand Prisma-ScR. Searches were performed by two reviewers in the PubMed,LILACS, Science Direct and BDTD databases by the association of descriptors, includingstudies according to the inclusion criteria. A total of 3,129 publications were identified,selecting 13 studies that highlighted spirituality/religiousness as a way to manage health care.Evidence revealed that religious practices, faith and beliefs feed spirituality with positivefeelings, providing an understanding of the health-disease process for managing choices, selfcareand coping with pathologies. This study contributes to the professionals' reflection,expanding the perspective of care in the spiritual dimension, as well as stimulating furtherfuture research.
Gender and feminist considerations in Artificial Intelligence from a developing-world perspective, with India as a case study
Authors: Kumar Shailendra , Choudhury Sanghamitra 
Published: November 2021

Abstract
The relationship between women, technology manifestation, and likely prospects in the developing world is discussed in this manuscript. Using India as a case study, the paper goes on to discuss how ontology and epistemology views utilised in AI (Artificial Intelligence) and robotics will affect women's prospects in developing countries. Women in developing countries, notably in South Asia, are perceived as doing domestic work and are underrepresented in high-level professions. They are disproportionately underemployed and face prejudice in the workplace. The purpose of this study is to determine if the introduction of AI would exacerbate the already precarious situation of women in the developing world or if it would serve as a liberating force. While studies on the impact of AI on women have been undertaken in developed countries, there has been less research in developing countries. This manuscript attempts to fill that need.
Multi-Photon Microscopy for the Evaluation of Interstitial Fibrosis in Extended Criteria Donor Kidneys: A Proof-of-Concept Study
Authors: So Wei Zheng , Teo Rachel Zui Chih , Ooi Li Yin , Goh Benjamin Yen Seow , Lu Jirong , Vathsala Anantharaman , Thamboo Thomas Paulraj , Tiong Ho Yee 
Published: November 2021

Abstract
Introduction:This study evaluated the initial use of label-free second harmonic generation (SHG) imaging with two-photon excitation (2PE) auto-fluorescence for the quantification of collagen/fibrosis on pre-implantation biopsies of extended criteria donors (ECD).Methods:A total of 22 core ECD kidney transplant biopsy specimen tissues from 7 ECD donors, taken at the time of pre-implantation were retrieved, cut into 5-micron sections, mounted on slides and deparaffinized. The core needle biopsies were imaged with 2X and 20X objective using the commercially available laser-based Genesis® 200 (Histoindex Pte Ltd and Clinnovate Pte Ltd, Singapore). The entire core was selected as the Region of Interest (ROI). Corresponding clinical information from transplant donors were retrieved. Histopathological review was performed, and all biopsies had Interstitial Fibrosis (IF)/Tubular Atrophy (TA) scores > 0. Collagen parameters measured included quantification by the Collagen Area Ratio in Tissue (CART) and qualitative measurements by Collagen Reticulation Index (CRI).Results: 20 explant core biopsies were extracted from 10 donor kidney samples, of which originated from 7 donors. Table 1 depicts the baseline ECD characteristics of the donors. For the kidneys with multiple biopsies done, we obtained an average score of the collagen parameters across the different samples. Biopsies classified with > 85% KDPI score had significantly higher CAR and CART than biopsies with ≤ 85% KDPI score.Conclusion:MPM is an evolving technology that enables the quantification of the amount (CART) and quality (CRI) of collagen deposition in unstained explant biopsies of ECD kidneys. This initial evaluation found significant differences in both parameters between ECD kidneys with more or less than 85% KDPI scores.
Tear-drop Fracture of the Axis: Non-operative Treatment of Two Cases : Case Report
Authors: Benammou Adnene , Elloumi Ahmed , Jaouadi Mohamed Amin , Bellil Mehdi , Kooli Mondher 
Published: November 2021

Abstract
Tear-drop fracture of the axis are rare. It is characterized by a fracture of the anterior-inferior corner of the C2 body. The mechanism is usually in extension which is different from the tear-drop of lower cervical spine. We report two cases of adults who sustained a road traffic accident. They did not have any neurological deficit. The diagnosis was made on radiological examination. They both were treated conservatively with rigid immobilization and recovered well. Tear-drop fracture of the axis are usually stable. Imagery is the key of the diagnosis. Neurological deficit is rare. Conservative management usually give good outcome for non-complicated cases.
Dynamic Evaluation of Policy Feasibility, Feedbacks and the Ambitions of COALitions
Authors: Bi Stephen , Bauer Nico , Jewell Jessica 
Published: November 2021

Abstract
The Paris Agreement prioritised international bottom-up climate negotiations. Meanwhile, research has asserted the coal exit as a prerequisite for Paris-consistent pathways. The Powering Past Coal Alliance (PPCA), an opt-in initiative toward phasing-out coal-fired electricity by mid-century, embodies both paradigms but currently encompasses just 5% of global coal demand. To assess its long-term prospects against Paris-consistent pathways, we couple the energy-economy model REMIND to an empirical coalition accession model and demonstrate a novel scenario analysis technique, Dynamic Policy Evaluation (DPE). Capturing co-evolutionary feedbacks between policy uptake and global energy markets, we simulate nationally-and-temporally-fragmented PPCA accession and analyse its sensitivity to coalition growth, sectoral ambition, and Covid-19-related uncertainty. Surprisingly, we find that virtually-global PPCA participation achieves <3% of 1.5oC-consistent coal declines, as non-electric consumption remains unregulated. In contrast, our median-estimate scenario (82% accession) assuming economy-wide coverage achieves ~53% efficacy (virtually-global: ~85%), suggesting that the PPCA should prioritise policy ambition over coalition expansion.
PGGHG and ODF3B as New Tumor Suppressor Genes in Renal Cell Carcinoma
Authors: mohammadisoleimani elham , Firoozi Zahra , Haghi-Aminjan Hamed , Naghizadeh Mohammad Mehdi , Zeighami Shahryar , Ariafar Ali , Mansoori Hosein , Daraei Abdolreza , Dastsooz Hassan , Mansoori Yaser 
Published: November 2021

Abstract
Background

Renal cell carcinoma (RCC) is the most frequent heterogeneous type of kidney cancer. Although the role of many genes in the development of RCC has been shown, its specific molecular mechanism is still unknown. In this research, we studied the expression profile of two poorly studied genes, PGGHG and ODF3B, with possible role in renal cancers in our RCC patients' tumors and adjacent normal tissues, as well as their clinicopathological features.
Materials and Methods

The PGGHG and ODF3B expression was determined using the quantitative real-time PCR in 40 tumor samples and their adjacent non-cancerous tissues. Moreover, Enrichr was used to investigate their pathways, ontologies, and possible upstream transcription factors. Furthermore, STRING was applied to search for interaction between PGGHG and ODF3B.
Results

The expression level of PGGHG and ODF3B was lower in the tumor tissues compared to their adjacent normal tissues. The expression level of ODF3B in the patients who had tumor size > 4cm was significant. Our data found the possible upstream transcription factor of ODF3B and PGGHG regulating their expression in biological pathways, mainly PPARG as the same upstream transcription factor affecting both genes. Moreover, our data revealed connection between protein networks of PGGHG and ODF3B. We found several main KEGG, biological process (BP), molecular function (MF), and cellular component (CC) for proteins involved in these networks.
Conclusion

PGGHG and ODF3B downregulation in RCC tumors suggests their possible tumor-suppressive role in RCC. More research is needed to determine the precise mechanism of their involvement in RCC pathogenesis.
Comparison of Staging Laparoscopy for Peritoneal Metastases with or without Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC)
Authors: Farinha Hugo Teixeira , Mattille Daphné , Mantziari Styliani , Demartines Nicolas , Hübner Martin 
Published: November 2021

Abstract
Background
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has been introduced for palliative treatment of peritoneal cancer (PC) and is currently tested also in the neoadjuvant and prophylactic setting. The aim was therefore to compare safety and tolerance of staging laparoscopy with or without PIPAC.
Methods
This retrospective analysis compared consecutive patients undergoing staging laparoscopy alone for oesogastric cancer with patients having PIPAC for suspected PC of various origins from January 2015 until January 2020. Safety was assessed by use of the Clavien classification for complications and CTCAE for capturing of adverse events. Pain and nausea were documented by use of a visual analogue scale (VAS: 0-10: maximal intensity).
Results
Overall, 25 PIPAC procedures were compared to 24 in the laparoscopy group. PIPAC procedures took a median of 35 min (IQR: 25-67) longer. Four patients experienced at least one complication in either (p=0.741). No differences were noted for postoperative nausea (p=0.961) and pain levels (p=0.156). Median hospital stay was 2 (IQR: 1-3) for PIPAC and 1 (IQR: 1-2) for the laparoscopy group (p=0.104).
Conclusions
The addition of PIPAC did not jeopardize safety and postoperative outcomes of staging laparoscopy alone. Further studies need to clarify its oncological benefits.
Association of Monocyte-Lymphocyte Ratio and Proliferative Diabetic Retinopathy in the U.S. Population with Diabetic Retinopathy
Authors: Huan Wang , Zhen Guo , Yu Xu 
Published: November 2021

Abstract
Diabetic retinopathy (DR) is one of the most common causes of blindness and visual impairment, especially proliferative diabetic retinopathy (PDR). Early prediction of its occurrence and progression is important. However, the association between monocyte-lymphocyte ratio(MLR) and PDR remains unclear. This study aimed to investigate the association between MLR and PDR in the U.S. population with DR from NHANES 2005 to 2008. DR was defined by the criteria of the Early Treatment for Diabetic Retinopathy Study based on nonmydriatic fundus photography. The MLR is the monocyte count/lymphocyte count. The lymphocyte count and monocyte count can be obtained directly from laboratory data files. Logistic regression was applied to explore the association between MLR and PDR. A total of 300 participants were included, the prevalence of PDR was 9%(27/300). In the multivariate regression models, patients with PDR was significantly associated with MLR (adjusted OR = 1.9, 95% CI: 1.26, 2.84) after adjusting all of the covariates. The interaction analysis showed an interactive role in the association between MLR and PDR by PIR(P for interaction=0.02). MLR were significantly associated with the occurrence of PDR in diabetic patients. The assessment of MLR levels might be a part of follow-up visits with diabetic patients.
White, beige and brown adipose tissue: structure, function, specific features and possibility formation and divergence in pigs
Authors: Chernukha Irina , Fedulova Liliya , Kotenkova Elena 
Published: November 2021

Introduction. Traditionally, mammalian adipose tissue is divided into white (white adipose tissue – WAT) and brown (brown adipose tissue – BAT). While the functions of WAT are well known as the triglyceride depot, the role of BAT in mammalian physiology has been under close investigation. The first description of the role of BAT in maintaining thermogenesis dates back to 1961. This article offers a review of structural and functional specificity of white, beige and brown adipose tissue.
Results and discussion. The differences and descriptions of adipocytes and their impact on the maintenance of the main functions of the mammalian body are described in this manuscript. In particular, thermogenesis, stress response, obesity, type II diabetes. In addition to WAT and BAT, an intermediate form was also detected in the body – beige fat (BeAT or Brite). The opposite opinions regarding the presence of three types of adipose tissue in the human and animal bodies are presented. Studies on the identification of uncoupling proteins 1 and 3 and their role in the transformation of white fat into beige/brown are considered. Basically, the data on the factors of endogenous and exogenous nature on their formation are given on the example of the human body.
Conclusion. With an abundance of publications on the keywords: “white, brown fat”, these studies, in the overwhelming majority, are devoted to the role of these fats in the formation of human thermogenesis, the assessment of the impact on obesity. Pigs have also been suggested to lack functional BAT, which is a major cause of neonatal death in the swine industry, therefore the focus on investigating role of different types of adipose tissue in pigs seems very promising in order to understand whether there is a compensating mechanism of thermogenesis.
Application of water quality index and multivariate statistical techniques for assessment of water quality around Yamuna River in Agra Region, Uttar Pradesh, India
Authors: Isaac Runit , Siddiqui Shaziya 
Published: November 2021

Abstract
In this research, water quality index and multivariate statistical techniques were carried out on 14 water quality parameters collected quarterly (four times/year) from nine water sources in Agra, Uttar Pradesh, India, for one year (May 2019–April 2020). The water quality parameters included are the concentration of hydrogen ions (pH), Electrical Conductivity, Turbidity, Total Dissolved Solids (TDS), Total Hardness, Total Alkalinity, Calcium, Sulphate, Chloride, Magnesium, Iron, COD, DO, and BOD. The water samples collected show that the mean values of physicochemical parameters are in the range set by WHO and BIS except for hardness in summer (1,680 mg/L), monsoon (832.22 mg/L), winter (1,876.66 mg/L), spring (1,535.55 mg/L); TDS in summer (1,000.33 mg/L), monsoon (683.44 mg/L), winter (1,087.66 mg/L), spring (776.66 mg/L); and sulphate in summer (927.22 mg/L), monsoon (446.77 mg/L), winter (925.77 mg/L), spring (944.88 mg/L), which indicate bad quality of water. The WQI values were calculated for three locations in different weather conditions. WQI values in summer, winter and spring are 630.90, 279.61, 279.91, showing that the river water is not suitable for drinking purposes whereas the WQI value in monsoon is 75.89, showing that water is fit for drinking purposes due to the dilution of the river water. A moderate positive correlation was observed for turbidity with total hardness, iron, total alkalinity, and sulphate. Negative correlation was observed with pH. Moderate correlation was seen with TDS–EC (0.608), TDS–Alkalinity (0.7794), EC–Ca (0.723), and strong correlation was observed for BOD–DO (0.941) and Ca–Mg (0.999). Principal component analysis revealed that five factors were significant (eigenvalue &gt; 0.5) with total variance of 39.43%–85.19% respectively. The ICP-MS study of water samples from point sources indicate the presence of Ni2+, Cr6+, Co2+, Mn2+, Cu2+, and Zn2+ ions at higher concentrations.
O RISCO DE DESASTRE TECNOLÓGICO NA PONTE NEWTON NAVARRO, NATAL – RN, BRASIL
Authors: Souza Jhonathan Lima de , Oliveira Francisca Leiliane Sousa de , Almeida Lutiane Queiroz de , Dantas de Medeiros Marysol 
Published: November 2021

O presente trabalho trata da temática de riscos tecnológicos associados a estruturas de pontes, a área de estudo em questão é a Ponte Newton Navarro e os riscos de colisões de navios nos pilares em função da ausência dos dispositivos de segurança. A metodologia do trabalho deu-se por meio de pesquisa bibliográfica documental em jornais e banco de dados públicos do Ministério Público do Rio Grande do Norte e da Secretaria de Meio Ambiente e Urbanismo de Natal, a análise do material pesquisado resultou no tratamento de imagens de plantas do projeto executivo da ponte, cartografia e a visita in loco, com suporte da Marinha do Brasil para verificar os pilares da ponte, o tratamento das informações basearam as análises e discussões desse texto, cujos resultados foram à constatação da ausência dos dispositivos de segurança desde o processo executivo da ponte.
Palavras-chave: Risco tecnológico, Vulnerabilidade estrutural, Ponte Newton Navarro.