bluuebunny/crossref_metadata_2025_split huggingface dataset:
Southern California Earthquake Data Now Available in the AWS Cloud
Authors: Yu Ellen , Bhaskaran Aparna , Chen Shang-Lin , Ross Zachary E. , Hauksson Egill , Clayton Robert W. 
Published: June 2021

Abstract
The Southern California Earthquake Data Center is hosting its earthquake catalog and seismic waveform archive in the Amazon Web Services (AWS) Open Dataset Program (s3://scedc-pds; us-west-2 region). The cloud dataset’s high data availability and scalability facilitate research that uses large volumes of data and computationally intensive processing. We describe the data archive and our rationale for the formats and data organization. We provide two simple examples to show how storing the data in AWS Simple Storage Service can benefit the analysis of large datasets. We share usage statistics of our data during the first year in the AWS Open Dataset Program. We also discuss the challenges and opportunities of a cloud-hosted archive.
La distancia y los negocios internacionales: análisis de las empresas exportadoras colombianas
Authors: Padilla-Naranjo Marly Julieth , Giraldo-Restrepo Paula Andrea , Vanegas-López Juan Gabriel , López Cadavid Diego Alejandro 
Published: June 2021

Many factors condition the decisions that firms make when expanding into different international markets, where the issue of distance plays a relevant role. The aim of this paper is to contribute to this issue by conducting an exploratory analysis of how distance affects the internationalization of companies that export from Colombia. In order to fulfill this objective, a detailed review of different related studies is carried out and a database is built with information at the firm level to find out if there is a relationship between the export variables compared with different characteristics of the exporter. As main results, it was found that the companies of nascent internationalization of the last years have reached more distant markets than those of greater antiquity, in particular those constituted after the year 1990, tendency that is explained mainly by the economic liberalization policies where Colombia opened unilaterally to the world market. Likewise, it was proved that, like several authors have pointed out in this literature review, the size of the companies conditions the reach of geographically more distant markets.
Der Demokratiebegriff und seine Profilierung im Deutschen und Polnischen. Eine kontrastive Analyse
Authors: Grzeszczak Monika 
Published: June 2021

Pojęcie demokracji i jego profilowanie w języku niemieckim i polskim. Analiza kontrastywna
Celem artykułu jest analiza kontrastywna rozumienia pojęcia demokracji w języku niemieckim i polskim oraz pokazanie sposobów jego konceptualizacji we współczesnym niemieckim i polskim dyskursie publicznym. Podstawę metodologiczną stanowią założenia lubelskiej etnolingwistyki kognitywnej. Materiał językowy został zaczerpnięty z trzech typów źródeł: ze słowników języka niemieckiego i polskiego, z empirycznych badań ankietowych oraz z tekstów prasowych. Na jego podstawie ustalono zespół podstawowych cech definicyjnych w rozumieniu ‘demokracji’ (tzw. zespół „cech bazowych”) wspólny różnym dyskursom w obu odnośnych językach. W kolejności wskazano zespoły cech przypisywanych ‘demokracji’ na gruncie wyspecjalizowanych dyskursów zróżnicowanych ideologicznie i światopoglądowo. Profilowanie pojęcia ‘demokracji’ zostało zarysowane na podstawie materiału tekstowowego zaczerpniętego z prasy niemieckiej i polskiej o orientacji liberalno-konserwatywnej i lewicowo-liberalnej.

Der Beitrag setzt sich zum Ziel, den Demokratiebegriff im Deutschen und Polnischen kontrastiv zu behandeln sowie die Arten seiner Konzeptualisierung im deutschen und polnischen öffentlichen Diskurs der Gegenwart aufzuzeigen. Die methodologische Grundlage bilden die Prämissen der Lubliner kognitiven Ethnolinguistik. Als Materialbasis dienen dabei drei Arten von Quellen, und zwar: Wörterbücher der deutschen und polnischen Sprache, experimentelle Befragungen sowie Pressetexte. Auf deren Grundlage wird ein Bündel von Grundeigenschaften (den sog. „Basiseigenschaften“) im Verständnis von ‚Demokratie‘ in beiden behandelten Sprachen festgelegt, das allen Diskursen gemeinsam ist. Im Anschluss daran wird auf die Merkmale von ‚Demokratie‘ hingewiesen, die in den ideologisch und weltanschaulich differenzierten Diskursen ans Licht kommen. Die Profilierung des Begriffs wird anhand des Textmaterials aus der deutschen und polnischen Presse mit folgender Ausrichtung skizzenhaft dargestellt: liberalkonservativ und linksliberal.
Wann wird Schweigen zum Sprechakt? Illokutionen im Grenzbereich sprachlichen Handelns
Authors: Topczewska Urszula 
Published: June 2021

Kiedy milczenie jest aktem mowy? Illokucje na pograniczu działań językowych
Celem artykułu jest ukazanie milczenia jako niewerbalnego pośredniego aktu mowy. Wielorakie funkcje semiotyczne milczenia pozwalają traktować je jako samodzielny segment w ciągu wypowiedzeń, któremu odpowiada działanie odrębne od poprzedzającego i/lub następującego po nim działania werbalnego. Interpretacja milczenia rzadko jednak opiera się wyłącznie na symbolicznych procedurach interpretacyjnych; milczenie jest zwykle interpretowane nie jako działanie symboliczne, lecz jako symptom intencji komunikacyjnych mówcy, który zaniechał aktu werbalnego.

Ziel des vorliegenden Beitrags ist es, zu zeigen, dass Schweigen im Gespräch ein indirekter Sprechakt im Sinne von Searle sein kann. Die vielfältigen semiotischen Funktionen von Sprechpausen, die in diesem Beitrag vorgestellt werden, legen nahe, dass es sich um ein unabhängiges Segment in einer Reihe von Äußerungen handelt, und somit um einen Sprechakt, der von den vorangehenden und folgenden verbalen Handlungen getrennt ist. Seine Interpretation hängt von Konventionen ab, die allerdings im Gegensatz zu direkten Sprechhandlungen selten ausschließlich symbolische Verfahren hervorrufen. In den meisten Fällen lösen Sprechpausen auch ein von Keller definiertes symptomatisches Interpretationsverfahren aus, das zu indirekten Schlussfolgerungen über die Kommunikationsabsichten der Sprecher führt.
Recurrent Dermatofibrosarcoma Protuberans of the Vulva: A Rare Occurrence and Review of Literature
Authors: Goyal Lajya Devi , Garg Priyanka , Kaur Manmeet , Sharma Diksha 
Published: June 2021

Objective: Dermatofibrosarcoma protuberans (DFSP) of the vulva is an uncommon soft tissue tumor with fewer than 60 cases reported previously. Distant metastasis is rare with a high propensity for local invasion. Surgical management is the gold standard with adequate margin excision to prevent future recurrences. We report a case of vulvar DFSP requiring three resections to achieve primary clearance. To the best of our knowledge, this is the first case report from India.
Case report: A 35-years-old female, presented with nodular vulvar mass for the third time arising from the upper part of right labia majora for the last year. She had a history of two similar episodes in the past for which excision was done and histopathology confirmed DFSP. The third wide local resection was performed with 3 cm margins and the margins were sent for intra-operative frozen section analysis, which was confirmed clear by the pathologist. The patient has been free of recurrence for two years.
Conclusion: DFSP is a challenging condition presenting as a non-tender nodular mass characterized by local invasion and recurrence. Early diagnosis and appropriate management using wide local excision with accurate margin assessment can achieve optimal results and prevent future recurrences.
Analysis of Students' Critical Thinking Abilities Using The PDEODE Strategy in Terms of Cognitive Style Through Online Learning
Authors: Wulandari Tabitha Sri Harteti 
Published: June 2021

The existence of the Covid-19 pandemic in 2020 resulted in learning being carried out on-line. However, critical thinking skills are still honed in the learning process. The purpose of this study was to obtain a description of the critical thinking skills of students of Mathematics Education 2019, PGRI Ronggolawe Tuban University in the Environmental Knowledge course using the PDEODE strategy on the Reflective cognitive style and Impulsive cognitive style. This type of research is descriptive exploratory research, Data collection techniques used MFFf (Matching Familiar Figures Test (MFFT) and critical thinking ability tests. The research subjects were 12 students. The results showed that: 1) There were 5 students with a reflective cognitive style and 7 students with an 9pulsive cognitive style. 2) The average results of critical thinking skills for all aspects of critical thinking components in the reflective cognitive style group are: 40% for high category 20% for moderate category 40% for low category while in the impulsive cognitive style group: 28.6% for high fJ.tegory 28.6% for medium category, and 42.8% for low category. The conclusion is that the PDEODE strategy can be applied in online learning to empower critical thinking ski! ls in terms of reflective and impulsive cognitive styles.
ICT and Economic Growth Nexus: Case of Central Asian Countries
Authors: Shodiev Tursun , Turayey Bakhodir , Shodiyev Kamoliddin 
Published: June 2021

The Government of Uzbekistan declared the year of 2020 as “The Year of Science, Education and Development of the Digital Economy” and is implementing the State Program, aiming at to liberalize the economy, improve market related incentives, encourage private enterprises, to reduce the role of the public sector by introducing ICT and Internet, developing digital economy. In order to understand the causal relationship between ICT investment and economic growth researchers have exert many effort in the world. The results are different: in developed countries the impact of ICT on economic growth is more powerful than in developing countries. This paper aims at finding and measuring causality between Economic growth and ICT development in emerging economies of Central Asian Countries by using panel data over the period of 19 years from 2000 – 2018. The research findings revealed that inflation, trade openness, final consumption expenditure and unemployment impact significantly on GDP per capita in Central Asian countries. The econometric analysis showed that ICT affects to GDP per capita positively and significantly: one percent increase in ICT contributes to GDP per capita 0.1669 percent (fixed broadband subscriptions) and 0.2218 percent (internet usage).Thus we concluded that information and communication technology together with economic indicators are key part of economic development in Central Asian countries. Reduction of inflation and unemployment allow expanding businesses, to create new job places in the digital economy.
Trace Elements and REY in the Muschelkalk Limestones of the Opole Silesia in Poland
Authors: Stanienda-Pilecki Katarzyna Jadwiga 
Published: June 2021

Abstract
The results of researches of the selected trace elements: Ti, Sr, Ba, Zn, and also Cr, Ni, Cu, Zr, Mo, Pb, Rb, Mn, Na, K, P, Y and REE (REY) content were presented in this article. The elements were measured in the carbonate minerals of Muschelkalk (Middle Triassic) limestones of the Opole Silesia in Poland, using two methods: ICP MS spectrometry and X-ray fluorescence. These methods are characterized by very high precision and sensitivity of measurements. The results of researches show that the content of analyzed trace elements varies in from value below 1 ppm up to some hundreds ppm. However, the highest contents were measured for strontium and barium, elements characteristic for aragonite carbonate phase which is transformed such as high-Mg calcite into low magnesium calcite during diagenesis. So as Sr and Ba indicate the presence of aragonite in the primary carbonate material. The other trace elements probably form substitutions in clay or carbonate minerals. Some of trace elements such as Zn, Pb, Cu, Mo, Ni may also be associated with sulfide minerals and Ti, Cr, Mn, with oxides. Some measured REY elements- Ce, Nd, Sm, Gd, Dy, Er and Y are found in the rocks in very small quantities. So their content is really very low. It varies in from value below 1 ppm up to 6 ppm. REY usually substitute Ca ions in calcite.
Research on EEG Features in Different Emotional States
Authors: Wang Xiaotian , Wang Zuo , Guo Jiawei , Pang Chunying , Liu Jikui 
Published: June 2021

Abstract
In order to improve the detection and treatment of neurological diseases effectively, it is a significant means to analysis EEG features. In this study, extrovert and stable persons were selected as the subjects according to the Eysenck Personality Questionnaire. Then set the subjects’ EEG signals in a quiet state with eyes closed as a reference group. Four types of pure music were selected as stimulus materials to induce four different kinds of emotions: pleasure, sadness, irritability, and fear. During the period, evoked EEG signals was acquired. Then, some signal processing methods were used to de-noise for EEG and separate EOG artifacts from EEG signals. Finally, EEG signals’ features in time domain, frequency domain and time-frequency domain were extracted, especially the method which combined Hilbert transform based on EMD with information entropy to calculate EEG signals’ Hilbert spectrum entropy for four emotional states. The results showed that EEG signals’ features in different emotional states changed with gender, brain and mood objectively, all differences mainly reflected in time domain features, frequency domain features and time-frequency domain features. All the results reveal that EEG signals’ variation characteristics in the process of auditory stimulation, and can be an adjustment basis for detection and treatment of neurological diseases.
Prognostic and Immunological Characterization of NSD3 Evaluated through an Integrative Pan-Cancer Analysis
Authors: Li Sha , Liu Yaqiong , Yao Chaoling , Xu Anji , Zeng Xiaoling , Ge Yuxin , Sheng Xiaowu , Zhang Hailin , Zhou Xiao , Long Ying 
Published: June 2021

Abstract
Background: Nuclear receptor binding SET domain protein-3 (NSD3) has been reported to be a crucial regulator of carcinogenesis as a histone lysine methyltransferase in multiple cancer types. However, the underlying mechanisms have not been clearly delineated. Therefore, we aimed to investigate the expression pattern, prognostic value, and potential function of NSD3 in 33 types of human cancer. Methods: The potential roles of NSD3 were explored using datasets from The Cancer Genome Atlas (TCGA) pan-cancer dataset and an array of bioinformatics methods, including analyses of the relationship between NSD3 expression and prognosis, tumor mutational burden (TMB), microsatellite instability (MSI), DNA amplification, and immune cell inﬁltration across 33 cancer types. Results: Many types of cancers are characterized according to the dysregulation of NSD3, which is associated with the pathological stage of cancer. Patients in our study with higher NDS3 levels, which were attributed to NSD3 copy number amplification, always experienced shorter survival periods. Additionally, NSD3 expression was associated with TMB and MSI in 10 different cancer types. The top five cancers whose NSD3 expression correlated with immune scores were further analyzed. The levels of immune-cell infiltration differed significantly between high and low NSD3-expressing samples in each of the five cancer types. Functional enrichment of the NSD3 co-expressed genes indicated a role for NSD3 in the regulation of immune responses and tumorigenesis. Conclusions: Our study revealed that NSD3 can function as a prognostic marker in various cancers due to its role in tumorigenesis and tumor immunity.
Effect of Season and Climate on in-hospital Mortality and Length of Stay for Patients With Type A Aortic Dissection
Authors: Luo Zeng-Rong , Lin Zhi-Qin , Chen Liang-wan , Qiu Han-Fan 
Published: June 2021

Abstract
Objective: To investigated the effects of seasonal and climatic changes on in-hospital mortality and length of stay (LOS) for postoperative patients with type A acute aortic dissection (AAD). Methods: The clinical data of 404 patients diagnosed with type A AAD in our hospital and the relevant meteorological data were retrospectively collected and analyzed from January 2016 to December 2019. Results: The multivariate unconditional logistic regression analysis showed that admission in autumn (OR=4.027, 95% CI=1.023-17.301) and coronary heart disease (odds ratio OR=7.669, 95% CI=1.20-48.689) were increased risk factors for postoperative in-hospital mortality in patients with type A AAD; admission in autumn (95% CI=2.719-7.921, P=0.041) and hypertension (95% CI=1.192-5.106, P=0.035) for type A AAD patients were increased risk factors for LOS. Conclusion: Patients with admission in autumn or coronary heart disease appeared to increasing effects on postoperative in-hospital mortality for type A AAD. Patients with admission in autumn or hypertension seemed to be associated with longer LOS.
Development of Ketoprofen-p-Aminobenzoic Acid Co-Crystal: Formulation, Characterization, Optimization and Evaluation
Authors: Bhatia Meenakshi , Kumar Ashwani , Kumar Vikas , Devi Sunita 
Published: June 2021

Abstract
Co-crystal is a promising class of solids that may provide options for improved properties. In the present study, ketoprofen- p-aminobenzoic acid (KP-PABA) co-crystal were prepared to sought enhanced solubility and dissolution rate of drug. KP-PABA co-crystal were prepared by solvent evaporation technique employing central composite experimental design, selecting independent variables as concentration of drug and PABA whereas dependent variables were assumed to be solubility and % drug release. The optimized batch as suggested by the experimental design was characterized by FTIR, DSC, XRD, SEM and NMR studies and further, evaluated for in-vitro and in-vivo anti-inflammatory and analgesic activities. The solubility and % drug release of different batches of co-crystal was found to be between 34.20-60.11 µg/ml and 68.11–93.45%, respectively. Co-crystal containing ketoprofen and PABA in molar ratio (1:1) was found to be optimized formulation batch. Physical characterization by X-ray diffraction spectra and differential scanning calorimetric studies confirms the crystallinity of prepared co-crystal. The half maximal inhibitory concentration (IC50) values for in-vitro anti-inflammatory activity comes out to be 34.04 µM for ketoprofen and 4.373µM for optimized formulation, exhibiting almost 8-fold amplification indicating higher anti-inflammatory effect of optimized batch as compared to drug ketoprofen. The results of in-vivo anti-inflammatory activity carried out by rat paw edema method revealed that the optimized batch of co-crystal preparation provided a significant % inhibition in paw volume in contrast to standard drug in wistar rats. In this case, a crystalline molecular complex of drug Ketoprofen, that demonstrate poor aqueous solubility, with p-aminobenzoic acid was recognized that further set out an improvement in solubility and also in anti-inflammatory activity of the drug in wistar rats.
Association Between The Triglyceride-Glucose (TyG) Index and Increased Blood Pressure in Normotensive Subjects: A Population-Based Study
Authors: Lee Dong-Hwa , Park Jong Eun , Kim So Young , Jeon Hyun Jeong , Park Jong-Hyock 
Published: June 2021

Abstract
Insulin resistance (IR) is an important contributor to the development of hypertension (HTN), and the triglyceride-glucose (TyG) index has been proposed as a simple, reliable marker of IR. This study investigated the association between the TyG index and blood pressure (BP) elevation in a large general population without a history of related diseases. The study enrolled 15,826 adults from the 2016–2019 Korea National Health and Nutrition Examination Survey (KNHANES). Participants were classified into quartiles based on the TyG index and BP was categorized as normal BP, elevated BP, pre-HTN, and HTN. The associations of the TyG index with BP categories were assessed using multivariate multinomial logistic regression models with normal BP as the reference group. The mean systolic/diastolic BP and prevalence of HTN increased with the TyG index. The continuous TyG index had a strong dose-response relationship with increased odds of elevated BP, pre-HTN, and HTN. Compared with the lowest TyG index quartile, the highest TyG index quartile was significantly associated with higher odds of having elevated BP (OR, 1.52; 95% CI, 1.23–1.87), pre-HTN (OR, 2.18; 95% CI, 1.91–2.48), and HTN (OR, 4.14; 95% CI, 3.40–5.02). Our study suggests that the TyG index is an early predictor of the risk of HTN.
Fatty Dihydropyridines With Anti-Hypertensive and Cardioprotective Potential During Ischemia and Reperfusion
Authors: Santa-Helena eduarda , Ribeiro Joaquim de Paula , Gioda Carolina Rosa , Cabrera Diego da Costa , D’Oca Marcelo G. Montes , Nery Luiz Eduardo Maia , Gonçalves Carla Amorim Neves 
Published: June 2021

Abstract
In this study, three fatty dihydropyridines, were tested for their anti-hypertensive and cardioprotective properties. Dihydropyridines 2c, 8c, and 9a contain the oleic chain and the nitro unit, the oleic chain and the chlorine unit, and the palmitic chain and the chlorine unit, respectively. For the experiments, animals were treated with N(ω)-nitro-L-arginine methyl ester to induce hypertension and after treated with the new dihydropyridine compounds and the standard drug nifedipine. Then, the heart was removed and subjected to global ischemia and reperfusion. Analyses of cardiac parameters were performed to monitor cardiac functionality; lactate dehydrogenase values were quantified in perfusates. After ischemia and reperfusion were performed, analyses to check the oxidative status and lipid damage. The results of the present study suggest that the new fatty DHPs have anti-hypertensive effects offering protection against ischemia to the heart of rats, accomplished by increasing antioxidants that defend and prevent the decline in cardiac function.
Characteristic and Interplay of Esophageal Microbiota in Esophageal Squamous Cell Carcinoma
Authors: Lin Zheng , Rao Wenqing , Xiang Zhisheng , Zeng Qiaoyan , Liu Shuang , Yu Kaili , Zhou Jinsong , Wang Jianwen , Chen Weilin , Chen Yuanmei , Peng Xiane , Hu Zhijian 
Published: June 2021

Abstract
Background: Esophageal squamous cell carcinoma(ESCC) is severe cancer in the world. The role of esophageal microbiota for ESCC is still uncertain. In the current study, 120 paired tissues from ESCC patients were collected, and 16s rRNA sequencing was performed to explore the esophageal microbiota. Results: The present investigation shows that the diversity and composition of the microbiota in ESCC cancerous tissues and para-cancerous tissues is significantly different, this variation between subjects beta diversity mainly explained by regions and sampling seasons. Species R.Mucilaginosa, P.Endodontalis, unclassified species in genus Leptotrichia, genus Phyllobacterium, and genus Sphingomonas were enriched in cancerous tissue. On the other hand, class Bacilli, N.Subflava, H.Pylori, A.Parahaemolyticus, A.Rhizosphaerae, unclassified species in genus Campylobacter and genus Haemophilus were increased in para-cancerous tissue. Compared with the co-occurrence network in cancerous tissue, a denser and more complex association network was formed in para-cancerous tissue. Moreover, the above differential taxa also participated in both co-occurrence network but played quite different roles. Finally, the functional association analyses revealed the altered signaling pathways in ESCCs were correlated to esophageal microbiota. Conclusion: Compared with para-cancerous tissues, microbiota in cancerous tissues showed significant differences in diversity and composition. The alterations in microbial co-occurrence network and functional pathways in ESCC tissues may be involved in carcinogenesis and the maintenance of local microenvironment for ESCC. These discoveries of the esophageal microbiota for ESCC patients may contribute to the etiology for ESCC prevention, diagnosis, early intervention, and treatment.