bluuebunny/crossref_metadata_2025_split huggingface dataset:
РУЙНУВАННЯ СТІНИ ЦЕГЛЯНОЇ БУДІВЛІ У ВИГЛЯДІ ПОЗДОВЖНЬОГО РОЗКОЛЮВАННЯ. ПРИЧИНИ, МЕТОДИ ВИЯВЛЕННЯ ТА ПІДСИЛЕННЯ
Authors: ЗЕЛЕНКО Є.В. , ЛІСЕНИЙ О.М. 
Published: April 2021

Викладені основні результати натурного інструментального обстеження адміністративної будівлі в м. Києві. Первісна проектна документація на будівлю за давністю не збереглася. При обстежені виявлено розкол у товщі кладки вздовж несучої цегляної зовнішньої стіни в рівні 1-го поверху. Два простінки внаслідок пошкоджень повністю втратили несучу здатність, повне їх руйнування не відбувається тільки за рахунок перерозподілу зусиль на сусідні простінки, поперечні стіни, перегородки тощо. Простінки несучої зовнішньої стіни, які зазнали пошкоджень, складені з різних матеріалів (кладка з жовтої цегли і кладка з червоної цегли). Визначені показники міцності матеріалів комплексної кладки стін: жовта керамічна цегла в кладці обрамлення віконних прорізів за міцністю на стиск відповідає марці 75; червона керамічна цегла в кладці простінків – марці 35. Пошкоджена частина стіни має вигин в бік вулиці. Для визначення геометричних параметрів вигину зовнішньої поверхні стіни були виконані вимірювання поздовжнього профілю стіни в трьох рівнях. Виявлено, що у рівні над карнизом стіна практично прямолінійна. В той же час, безпосередньо під карнизом горизонтальні зміщення стіни назовні складають до 68 мм. На рівні цокольного пояска зміщення стіни назовні складають до 20 мм. Проведені розрахунки міцності елементів несучих стін, згідно з якими несуча здатність не забезпечується, значення коефіцієнтів перевантаження сягають до k = 1,402 > 1. Проаналізовані результати багаторічного моніторингу вертикальних осідань будівлі. Характер руйнування простінків і підкарнизної ділянки стіни 1-го поверху обумовлений конструкцією цієї стіни. Руйнування стіни в рівні 1-го поверху відбулося шляхом утворення вертикальних поперечних тріщин у простінках по межі кладки обрамлення вікон з жовтої цегли, а також утворення поздовжнього розриву простінків та надвіконної частини стіни з загальною орієнтацією між концентраторами напружень – кут над карнизом, де відбувається зміна товщини стіни, і підвіконними нішами. На підставі результатів обстеження та розрахунків встановлені причини аварійного стану стіни. Був зроблений висновок, що всі простінки стін 1-го поверху потребують підсилення, з врахуванням перевантаження за розрахунком, також рекомендоване підсилення простінків стін 2-го поверху. Надані рекомендації щодо підсилення несучих стін будівлі при пошкодженні у вигляді поздовжнього розколу.
ВИПРОБУВАННЯ ФРАГМЕНТУ ВЕНТИЛЬОВАНОЇ УТЕПЛЕНОЇ ФАСАДНОЇ СИСТЕМИ З АЛЮМІНІЄВИМ КАРКАСОМ І ОПОРЯДЖЕННЯМ ПЛИТАМИ ПРИРОДНОГО КАМЕНЮ
Authors: ЖАРКО Л.О. , ОВЧАР В.П. , БЄЛОКОНЬ А.М. , ТАРАСЮК В.Г. 
Published: April 2021

Розглянуто результати експериментальних досліджень роботи енергозберігаючої фасадної вентильованої системи Hilti з прихованим кріпленням плит опорядження природного каменю на каркасі з алюмінієвих елементів за допомогою аграфів. Зразок фрагмента фасадної системи розмірами 4×2 м випробували на стенді в горизонтальному положенні на комплексну дію власної ваги, обледеніння та вітру від розрахункових навантажень експлуатаційних і граничних, позитивних і негативних, в рядовій і кутовій зонах будівлі. Наведені розрахунки навантажень, випробувальне обладнання, схеми випробувань та схеми розміщення вимірювальних приладів. Визначено фізико-механічні характеристики природного каменю плит опорядження. Опорядження випробуваного зразка складали 4 плити розмірами 2035×890×30 мм, масою по 122,5 кг. Визначено величини деформацій опорядження та представлено їх вичерпний аналіз. Руйнівне навантаження в площині плит становило 46,6 кН, що відповідає висоті будівлі 27 м. Характер руйнування зразка – деформація аграфів із вертикальним переміщенням та з розривом з’єднання направляючого аграфного профілю з несучим. Хімічні анкери плит опорядження витримали без пошкодження на вирив вітрове від’ємне навантаження 0,652 кН та на зріз вертикальне навантаження 1,664 кН. Випробуваннями зразка фрагменту фасадної системи встановлено, що система витримала всі передбачені види навантажень експлуатаційних і граничних від власної ваги, двостороннього зледеніння облицювання, вітрового навантаження позитивного і негативного на рядових і кутових ділянках. Під час проектування, монтажу та експлуатації цієї фасадної системи слід враховувати її вразливості: масивність опорядження, надійність з’єднань несучих і аграфних профілів каркасу та самих аграфів, можливість конструктивного забезпечення від зледеніння горизонтальних проміжків між плитами на рівні поверхів.
Status of Immunotherapy Acceptance in Chinese Patients With Multiple Sclerosis: Analysis of Multiple Sclerosis Patient Survival Report 2018
Authors: Zhou Ran , Zeng Qiuming , Yang Huan , Xu Yan , Tan Guojun , Liu Hongbo , Wang Lihua , Zhou Hongyu , Zhang Meini , Feng Jinzhou , Jin Tao , Zhang Xinghu , Wang Jiawei , Zhang Xu , Gao Feng , Yang Chunsheng , Bu Bitao , Li Chunyang , Zhang Min , Dong Huiqing , Lin Aiyu , Liu Weibin , Wu Lei , Wang Manxia , Tang Yulan , Wang Honghao , Long Youming , Wang Zhe , Zheng Weihong 
Published: April 2021

Objective: The prevalence of multiple sclerosis (MS) in China is low, although it has been increasing recently. Owing to the paucity of data on immunotherapy acceptance in the Chinese population, we conducted this study to analyze factors affecting the acceptance of immunotherapy and selection of disease-modifying therapies (DMTs) based on personal and clinical data of patients with MS.Methods: In this study, data were obtained from the Multiple Sclerosis Patient Survival Report 2018, which was the first national survey of patients with MS in China. There were 1,212 patients with MS from 31 provinces who were treated at 49 Chinese hospitals over a 4-month period from May 2018 to August 2018, and the patients were asked to complete online questionnaires to assess their understanding of the disease.Results: In general, highly educated patients with frequent relapses were more willing to receive treatment regardless of DMTs or other immunotherapy, and patients with more understanding of the disease opted to be treated. Younger patient population, patients with severe disease course, and those with more symptoms were likely to choose the treatment. Moreover, a higher proportion of women chose to be treated with DMTs than with other immunotherapies.Conclusions: Education status and patient awareness of the disease impact the treatment acceptance in Chinese patients with MS. Therefore, we call for improving the awareness of MS disease and social security to help patients to improve their quality of life.
Determinants of Junk Food Consumption Among Adolescents in Pokhara Valley, Nepal
Authors: Bohara Suraj Sujan , Thapa Kanchan , Bhatt Laxman Datt , Dhami Shankar Singh , Wagle Shreejana 
Published: April 2021

Background: Junk food consumption and its consequences has become a major public health concern globally because of its deteriorating health consequences and surging prevalence. Though its adverse health consequences are widely prevalent in all age groups, children and adolescents are more at risk. It may lead to obesity and act as a risk factor for different non-communicable diseases (NCD's) like heart diseases, cardiovascular disease, cancer, hypertension, diabetes, etc. This study was carried out to explore the junk food consumption and its associated factors among adolescent students.Methods: A cross-sectional study was conducted among 538 adolescent students of Kaski district, Nepal. We used a stratified proportionate sampling technique to recruit the participants. A self-administered questionnaire was used for data collection. Descriptive and bivariate statistical analysis was performed. The odds ratio was computed to test the association.Results: The study found that more than half of the participants (60.30%) consumed junk foods over the last 30 days, more prevalent among public school participants (65.1%) followed by participants of private school (56.3%). More than half of the participants consumed salty snacks (58.7%) followed by sweets (57.5%). The time of consumption was found to be higher together with friends (83.9%). Similarly, it was consumed more while the participants were on a trip (70.1%). Consumption of junk foods was significantly associated with public school (OR: 1.44, CI = 1.01–2.06), single family (OR: 1.46, CI = 1.01–2.10), living with parents (OR: 1.64, CI = 1.03–2.63), while on travel (OR: 1.99, CI = 1.33–2.98), while reading (OR: 2.01, CI = 1.16–3.47), at home (OR: 2.20, CI = 1.53–3.16), at school (OR: 2.86, CI = 1.98–4.12), friends' influence (OR: 2.01, CI = 1.37–2.94), and junk food availability at home (OR: 1.92, CI = 1.33–2.76).Conclusion: Consumption of junk foods among adolescent students was remarkably high in both public school and private school adolescents. Regardless of adequate knowledge on harmful consequences of junk foods, school-going adolescents are consuming junk foods due to its easy availability and ready-to-use packaging. The government of Nepal should strictly standardize and regulate advertising policies and extravagant health claims advertised by junk food manufacturers. An appropriate intervention targeted to adolescents to improve food behaviors is recommended.
Off-Label Use of Antineoplastic Drugs to Treat Malignancies: Evidence From China Based on a Nationwide Medical Insurance Data Analysis
Authors: Wei Guoxu , Wu Min , Zhu He , Han Sheng , Chen Jing , Zhai Chenchen , Shi Luwen 
Published: April 2021

Purpose: Cancer is a leading cause of morbidity and mortality worldwide. Off-label (OL) use of antineoplastic drugs to treat malignancies is prevalent. In this study, we quantified and characterized OL use of antineoplastic drugs to treat malignancies in China.Methods: This was a retrospective study using nationwide data collected from 2008 to 2010. Use of antineoplastic drugs was considered OL if they were used for indications not reflected in the package insert published by the National Medical Products Administration at the time of prescription. Descriptive analysis and Spearman rank correlation were used to evaluate the frequency and pattern of OL drug use.Results: In total, 51,382 patients with malignancies, 24 categories of antineoplastic drugs, and 77 types of malignancies treated with OL drugs were included in this study. Twenty commonly used antineoplastic drugs (ICD encoded as L01) were used OL in 10–61% of cases, and four commonly used endocrine therapy antineoplastic drugs (ICD encoded as L02) were used OL in 10–19% of cases. There was a significant negative correlation between the disease constituent ratio and the average OL use rate of antineoplastic drugs for various malignancies. In contrast, there was a significant positive correlation between the average OL use rate of antineoplastic drugs and the number of malignancies treated with OL drugs.Conclusion: This study provided information regarding OL use of antineoplastic drugs for treatment of malignancies, and showed that OL use was prevalent. In addition, uncommon malignancies were more likely to be treated with OL antineoplastic drugs. Furthermore, more commonly used antineoplastic drugs were more likely to be used OL.
Functional Polymorphisms in Oxytocin and Dopamine Pathway Genes and the Development of Dispositional Compassion Over Time: The Young Finns Study
Authors: Dobewall Henrik , Saarinen Aino , Lyytikäinen Leo-Pekka , Keltikangas-Järvinen Liisa , Lehtimäki Terho , Hintsanen Mirka 
Published: April 2021

Background:We define compassion as an enduring disposition that centers upon empathetic concern for another person's suffering and the motivation to act to alleviate it. The contribution of specific candidate genes to the development of dispositional compassion for others is currently unknown. We examine candidate genes in the oxytocin and dopamine signaling pathways.Methods:In a 32-year follow-up of the Young Finns Study (N= 2,130, 44.0% men), we examined with multiple indicators latent growth curve modeling the molecular genetic underpinnings of dispositional compassion for others across the life span. We selected five single nucleotide polymorphisms (SNPs) whose functions are known in humans: rs2268498 (OXTR), rs3796863 (CD38) (related to lower oxytocin levels), rs1800497 (ANKK1/DRD2), rs4680 (COMT), and rs1611115 (DBH) (related to higher dopamine levels). Compassion was measured with Cloninger's Temperament and Character Inventory on three repeated observations spanning 15 years (1997–2012). Differences between gender were tested.Results:We did not find an effect of the five SNPs in oxytocin and dopamine pathway genes on the initial levels of dispositional compassion for others. Individuals who carry one or two copies of the T-allele of DBH rs1611115, however, tend to increase faster in compassion over time than those homozygotes for the C-allele, b = 0.063 (SE = 0.027;p= 0.018). This effect was largely driven by male participants, 0.206 (SE = 0.046;p&lt; 0.001), and was not significant in female participants when analyzed separately.Conclusions:Men who are known to have, on average, lower compassion than women seem to reduce this difference over time if they carry the T-allele of DBH rs1611115. The direction of the association indicates that dopamine signaling activity rather than overall dopamine levels might drive the development of compassion.
Art Therapy in the Digital World: An Integrative Review of Current Practice and Future Directions
Authors: Zubala Ania , Kennell Nicola , Hackett Simon 
Published: April 2021

BackgroundPsychotherapy interventions increasingly utilize digital technologies to improve access to therapy and its acceptability. Opportunities that digital technology potentially creates for art therapy reach beyond increased access to include new possibilities of adaptation and extension of therapy tool box. Given growing interest in practice and research in this area, it is important to investigate how art therapists engage with digital technology or how (and whether) practice might be safely adapted to include new potential modes of delivery and new arts media.MethodsAn integrative review of peer-reviewed literature on the use of digital technology in art therapy was conducted. The methodology used is particularly well suited for early stage exploratory inquiries, allowing for close examination of papers from a variety of methodological paradigms. Only studies that presented empirical outcomes were included in the formal analysis.FindingsOver 400 records were screened and 12 studies were included in the synthesis, pertaining to both the use of digital technology for remote delivery and as a medium for art making. Included studies, adopting predominantly qualitative and mixed methods, are grouped according to their focus on: art therapists’ views and experiences, online/distance art therapy, and the use of digital arts media. Recurring themes are discussed, including potential benefits and risks of incorporating digital technology in sessions with clients, concerns relating to ethics, resistance toward digital arts media, technological limitations and implications for therapeutic relationship and therapy process. Propositions for best practice and technological innovations that could make some of the challenges redundant are also reviewed. Future directions in research are indicated and cautious openness is recommended in both research and practice.ConclusionThe review documents growing research illustrating increased use of digital technology by art therapists for both online delivery and digital art making. Potentially immense opportunities that technology brings for art therapy should be considered alongside limitations and challenges of clinical, pragmatic and ethical nature. The review aims to invite conversations and further research to explore ways in which technology could increase relevance and reach of art therapy without compromising clients’ safety and key principles of the profession.
Gene Expression Differences Between Young Adults Based on Trauma History and Post-traumatic Stress Disorder
Authors: Bountress Kaitlin E. , Vladimirov Vladimir , McMichael Gowon , Taylor Z. Nathan , Hardiman Gary , Chung Dongjun , Adams Zachary W. , Danielson Carla Kmett , Amstadter Ananda B. 
Published: April 2021

Background:The purpose of this study was to identify gene expression differences associated with post-traumatic stress disorder (PTSD) and trauma exposure (TE) in a three-group study design comprised of those with and without trauma exposure and PTSD.Methods:We conducted gene expression and gene network analyses in a sample (n= 45) composed of female subjects of European Ancestry (EA) with PTSD, TE without PTSD, and controls.Results:We identified 283 genes differentially expressed between PTSD-TE groups. In an independent sample of Veterans (n= 78) a small minority of these genes were also differentially expressed. We identified 7 gene network modules significantly associated with PTSD and TE (Bonferroni correctedp≤ 0.05), which at a false discovery rate (FDR) ofq≤ 0.2, were significantly enriched for biological pathways involved in focal adhesion, neuroactive ligand receptor interaction, and immune related processes among others.Conclusions:This study uses gene network analyses to identify significant gene modules associated with PTSD, TE, and controls. On an individual gene level, we identified a large number of differentially expressed genes between PTSD-TE groups, a minority of which were also differentially expressed in the independent sample. We also demonstrate a lack of network module preservation between PTSD and TE, suggesting that the molecular signature of PTSD and trauma are likely independent of each other. Our results provide a basis for the identification of likely disease pathways and biomarkers involved in the etiology of PTSD.
Prenatal and Intrapartum Factors Associated With Infant Temperament: A Systematic Review
Authors: Takegata Mizuki , Matsunaga Asami , Ohashi Yukiko , Toizumi Michiko , Yoshida Lay Myint , Kitamura Toshinori 
Published: April 2021

Background:Temperament involves individual variations in behavioural tendencies of emotional responses and reactions to stimuli after birth. Because ‘foetal programming' is a strong hypothesis in developing temperament, prenatal and intrapartum factors may be significant determinants of infant temperament. This systematic literature review aims to elucidate the evidence of prenatal and intrapartum predictors, including genetic, biological, environmental, socio-demographic, psychological, and obstetric factors of parents and their child.Methods:Relevant articles were searched using MEDLINE, PubMed, and SCOPUS. The inclusion criteria were (a) original research article, (b) written in English, (c) assessed the temperament of infants 12 months old or younger as an outcome variable, and (d) investigated prenatal and intrapartum factorial variables of infant temperament. Following the PRISMA guideline, the articles found in the three databases were screened and selected according to the inclusion and exclusion criteria before the final review.Results:Finally, 35 articles were reviewed. This systematic review identified a variety of prenatal and intrapartum factors that were significantly associated with infant temperament: (1) genetic and biological factors: certain genotypes, maternal cortisol and ACTH, and CRHs, (2) environmental factors: substance use such as tobacco, alcohol, and illegal drugs, (3) socio-demographic factor: lower-income, (4) psychological factors: depression or anxiety, eating disorders, personality types of mothers, and domestic violence, and (5) obstetric factors: foetal growth (birth weight), hypertension in mothers, nausea (emesis), and preterm birth.Conclusion:The findings support gene-environment interaction and biological mechanisms for developing infant temperament, suggesting the importance of ensuring a safe and comfortable environment for pregnant mothers, unborn infants, and families during pregnancy and delivery.
FaceGuard: A Wearable System To Avoid Face Touching
Authors: Michelin Allan Michael , Korres Georgios , Ba’ara Sara , Assadi Hadi , Alsuradi Haneen , Sayegh Rony R. , Argyros Antonis , Eid Mohamad 
Published: April 2021

Most people touch their faces unconsciously, for instance to scratch an itch or to rest one’s chin in their hands. To reduce the spread of the novel coronavirus (COVID-19), public health officials recommend against touching one’s face, as the virus is transmitted through mucous membranes in the mouth, nose and eyes. Students, office workers, medical personnel and people on trains were found to touch their faces between 9 and 23 times per hour. This paper introduces FaceGuard, a system that utilizes deep learning to predict hand movements that result in touching the face, and provides sensory feedback to stop the user from touching the face. The system utilizes an inertial measurement unit (IMU) to obtain features that characterize hand movement involving face touching. Time-series data can be efficiently classified using 1D-Convolutional Neural Network (CNN) with minimal feature engineering; 1D-CNN filters automatically extract temporal features in IMU data. Thus, a 1D-CNN based prediction model is developed and trained with data from 4,800 trials recorded from 40 participants. Training data are collected for hand movements involving face touching during various everyday activities such as sitting, standing, or walking. Results showed that while the average time needed to touch the face is 1,200 ms, a prediction accuracy of more than 92% is achieved with less than 550 ms of IMU data. As for the sensory response, the paper presents a psychophysical experiment to compare the response time for three sensory feedback modalities, namely visual, auditory, and vibrotactile. Results demonstrate that the response time is significantly smaller for vibrotactile feedback (427.3 ms) compared to visual (561.70 ms) and auditory (520.97 ms). Furthermore, the success rate (to avoid face touching) is also statistically higher for vibrotactile and auditory feedback compared to visual feedback. These results demonstrate the feasibility of predicting a hand movement and providing timely sensory feedback within less than a second in order to avoid face touching.
Analysis of Indian Bank Customer’s Attitude towards E-Banking
Authors: Prasanth S , Sudhamathi S 
Published: April 2021

The banks acquired the capacity to efficiently cut costs through the introduction of E-banking technologies, to extend its reach to manage its everyday banking needs by way of the use of online banking platforms. This paper analyses Indian bank customer’s attitudes towards e-banking. A big part of why people tend to do banking at home or the ATM is that they feel like they should go at a time that is more convenient for them, rather than coming to the branch. This paper found how the impression of banking facilities that students get is affected by choice of banks they use. The researcher has used a proportionate stratified random sampling method, which is more effective for correctly selecting respondents. The data were obtained 120 individuals applying for a bank loan in India through online banking. In this category of 120, only those who replied arecited by the report. Then the data processing was performed using the Multivariate Analysis Test, the NSQ, and the Kolmogorov-Smirnov analyses. Through this research, it was determined that youth, ethnicity, and income play a major role in online banking.