bluuebunny/crossref_metadata_2025_split huggingface dataset:
Виконавська інтерпретація та інтенція як види художньої діяльності у вокальному мистецтві
Authors: Могилевська Наталія 
Published: November 2021

Мета дослідження – обґрунтувати наявність і важливість виконавської інтерпретації та інтенції як основних видів художньої творчості у вокальному мистецтві. Методи дослідження. У процесі розв’язання завдань статті використано загальнонаукові, зокрема аналіз, синтез, інтерпретацію та узагальнення результатів, та спеціальні методи дослідження. Міждисциплінарне використання методологічного інструментарію мистецтвознавства, психолінгвістики, філософії мистецтва тощо дало змогу обґрунтувати наявність і значення виконавської інтерпретації та інтенції в мистецтві вокаліста. Зокрема, для концептуалізації уявлення про інтерпретацію та інтенції вокаліста застосовано психосемантичні методи, які досліджують свідомість, мотивацію, емоції особистості. Наукова новизна полягає в обґрунтуванні наявності та важливості виконавської інтерпретації та інтенції в мистецтві вокаліста. Висновки. Зазвичай музично-пісенний твір дає змогу виконавцю-вокалісту насамперед виразити власні погляди, переживання, відчуття, наміри і т. ін. Тому вираження свого внутрішнього світу, свого світовідчуття, утвердження свого «я» опосередковано (через інтерпретацію музичного твору) – чи не основне завдання, яке має розв’язати виконавець. Часто саме так музично-пісенний текст, який інтерпретує вокаліст, передусім стає засобом вираження його глибинних ментально-когнітивних намірів, тобто інтенцій. Тому в закладах підготовки майбутніх вокалістів повинні звертати увагу на забезпечення умов для ментально-ціннісного розвитку студентів і формування у них відповідного духовного світогляду.
Evaluation of the diagnostic efficiency of systemic immune-inflammation index in prostate biopsy
Authors: DEMİR Mehmet , YAĞMUR İsmail , PELİT Eyyup Sabri , KATI Bülent , ALBAYRAK İbrahim Halil , ÇİFTÇİ Halil 
Published: November 2021

Aim: This study aimed to evaluate the diagnostic efficacy of systemic immune-inflammation index (SII) in patients with prostate cancer (PCa) who have undergone prostate biopsy and have a prostate-specific antigen (PSA) value of 4–10 ng/ml.
Material and Method: In this study we included patients with a PSA value of 4–10 ng/mL, who underwent transrectal ultrasound-guided 12-core prostate biopsy between January 2010 and March 2021. The patients were divided into two groups as those with and without cancer. Those with cancer were divided into two groups as low grade (grade 1 and 2) and high grade (grade 3–5) according to the International Society of Urologic Pathologists (ISUP) grades. PSA, neutrophil-lymphocyte ratio (NLR), prostate volume, platelet-to-lymphocyte ratio (PLR) and SII were compared between the groups.
Results: The mean age of the 182 patients included in the study was 63.4±8.0 years, and the mean PSA value was 6.69±2.45 ng/mL. Benign prostate disease were detected in 142 (78%) of the patients and PCa in 40 (22%) patients. PSA, PLR, NLR and SII did not differ in those with cancer. Low ISUP grade cancer was detected in 80% of the patients and high ISUP grade cancer in 20%. PSA and PLR values were significantly higher in patients with high ISUP grade PCa compared to those with low ISUP grade (p < 0.05). There was no difference in SII values between the two groups. PSA, PLR and SII values of patients with high ISUP grade PCa were significantly higher than those without cancer (p
PERENCANAAN DAN STRATEGI KOMUNIKASI DALAM MENINGKATKAN ADAPTIFITAS SUMBERDAYA MANUSIA DAN KEUNGGULAN KOMPETITIF LEMBAGA
Authors: Pranawukir Iswahyu 
Published: November 2021

Planning and communication strategies are one of the keys in increasing adaptability in an institution or organization, including Islamic boarding schools. The purpose of this study is to determine the planning and communication strategies in increasing the adaptability of human resources and competitiveness of the Madinatul Qur'an Islamic boarding school in Depok. Through qualitative descriptive method, the results of planning and communication strategies are obtained according to the stages. The planning stage is to formulate the scientific, capacity and character building. The strategy formulation stage produces an aggressive strategy, involving HR target as partners with various stimuly, refresher strategy through social service practices, growth strategy through the development of intellectual, religious, humanist and adaptive character; defensive strategies through interdisciplinary and transdisciplinary training. Furthermore, the stages of personal competence, through improving communication, managerial and business skills, control stages that focus on the uniqueness of tahfidz, the supervision stage, in the form of optimizing the role of HR and the evaluation stage, in order to encourage the sensitivity of HR to technological developments. Lastly is the communication strategy stage. The graduates of Ma'had Aly will be facilitated with a bachelor degree In order to fulfill the stakeholders’ demand.
O EXERCÍCIO DA POSSE DA PROPRIEDADE PRIVADA IMOBILIÁRIA E A NATUREZA
Authors: Cini Marchionatti Carlos , Cansi Francine , Cruz Paulo Márcio 
Published: November 2021

O instituto jurídico da Propriedade Privada Imobiliária exerce-se segundo a sua função social. A investigação que justifica este trabalho científico corresponde à indagação: é bastante o exercício da propriedade segundo a sua função social? Mais do que atender à função social, a Propriedade Privada Imobiliária deve atender às exigências necessárias à preservação da vida. Corresponde ao exercício da posse da Propriedade Privada Imobiliária segundo a qual se evitem tragédias e se justifica o acréscimo de parágrafo ao artigo 1.228 do Código Civil. A metodologia do trabalho observa a base lógica dedutiva na pesquisa e no conteúdo escrito.
Palavras-Chave: Propriedade Privada Imobiliária. Função Social. Meio Ambiente. Preservação da vida.

Abstract: The legal institute of Real Estate Private Property is understood according to its social role. The investigation which leads to the purpose of this scientific paper is: is the exercise of the property according to its social role enough to justify it? More than attending to its social role, the institute of Real Estate Private Property must observe the necessary demands related to life preservation. This corresponds the exercise of the tenure in order to avoid tragedies justifying the addition of a paragraphe to article 1.228 of the Code Civil. The methodology observes the logical deductive data in the research and in the context written.
Keywords: Real Estate Private Property. Social role. Environmental. Life preservation.
Analisis Kesulitan Guru Biologi Mengajar Di SMA Negeri Kota Lubuklinggau Selama Masa Pandemi Covid-19
Authors: Yantari Nevi , Widiya Mareta , Sepriyaningsih Sepriyaningsih 
Published: November 2021

Penelitian ini bertujuan untuk mengetahui kesulitan guru biologi mengajar di SMA Negeri Kota Lubuklinggau pada masa pandemi Covid-19. Metode penelitian ini menggunakan pendekatan kualitatif deskriptif. Teknik pengumpulan data ialah menggunakan observasi, wawancara, angket, dan dokumentasi. Populasi pada penelitian ini adalah seluruh guru biologi di SMA Negeri 1, 2, 4, 5, 6, 7, dan 8 Kota Lubuklinggau. Sampel pada penelitian ini adalah 15 guru biologi dari SMA Negeri Kota Lubuklinggau. Berdasarkan hasil analisis kesulitan dibagi menjadi lima aspek indikator (media, motivasi, sikap, kreativitas, dan sarana prasarana). Hasil persentase setiap SMA Negeri Kota Lubuklinggau telah mencakup dari lima aspek indikator, guru SMA Negeri 1 (14%), guru SMA Negeri 2 (36%), guru SMA Negeri 4 (31%), guru SMA Negeri 5 (27%), guru SMA Negeri 6 (28%), guru SMA Negeri 7 (31%), dan guru SMA Negeri 8 (22%). Dapat disimpulkan setiap guru biologi di SMA Negeri Kota Lubuklinggau mengalami sedikit kesulitan dalam proses pembelajaran daring selama masa pandemi Covid-19. Kesulitan yang paling rendah terdapat pada guru SMA Negeri 1 Lubuklinggau dengan persentase 14% dan SMA Negeri 2 Kota Lubuklinggau memiliki persentase kesulitan paling tinggi sebesar 36%.Keywords: Kesulitan guru biologi, pembelajaran daring
Avaliação de dois programas de treinamento físico − concorrente e aeróbico − em mulheres obesas ou com sobrepeso portadoras da síndrome dos ovários policísticos
Authors: Santos Danielle Barbosa , Silva Laurilene Costa , Santos Denise Barbosa , Trindade Fabio Rodrigues , Lopes Ione Maria Ribeiro Soares 
Published: November 2021

Introdução: A Síndrome dos Ovários Policísticos (SOP) é um distúrbio endócrino, heterogêneo, cuja etiologia é desconhecida e com alta variação fenotípica .O tratamento de primeira linha para esta doença é o treinamento físico. Objetivo: Avaliar dois tipos de treinamentos físicos, concorrente e aeróbico, em mulheres obesas e com sobrepeso com SOP. Metodologia: Trata-se de um estudo clínico, analítico, prospectivo, controlado e randomizado, utilizando protocolos de treinamentos no “antes-depois”, onde utilizou-se o treinamento aeróbico, que é a utilização do oxigênio como fonte de energia, e o treino concorrente, que é a utlização de treino de força e treino aeróbico. Foram selecionadas 30 mulheres, nas quais 14, aproximadamente, 47% do total de pacientes participaram efetivamento do programa, com idade entre 18 e 40 anos com SOP obesas e/ou sobrepeso e posteriormente randomizadas para o Grupo I e Grupo II: a avaliação dos efeitos dos dois treinamentos, concorrente e aeróbico, sobre os parâmetros antropométricos, metabólicos e hormonais foi feita através de protocolos específicos para os treinos aeróbicos e concorrente. Foi utilizado para análise estatística o programa IBM SPSS versão 27.0. A distribuição normal dos dados foi realizado pelo teste de Shapiro-Wilk e para avaliar a mudança significativa da variável pós-intervenção, foi aplicado o teste t-student pareado. Resultados: Houve diferenças estatisticamente significante das variáveis estudadas nos parâmetros antropométricos no Treinamento Concorrente (TC) e Treinamento Aeróbico (TA) como peso, Índice de Massa Corporal (IMC), idade metabólica e gordura.O perfil da amostra demonstrou que dentre as selecionadas, a maioria (42,86%) possuía ensino superior, (57,14%) se autodeclararam negras e (100%) eram sedentárias.Comparando-se o TA e TC relativo aos parâmetros antropométricos, os grupos apresentaram homogeneidade, com diferença somente na coxa D(P=0,038). Conclusão: Os treinamentos físicos concorrentes e aeróbicos realizados três vezes por semana durante três meses reduzem de forma significativa vários parâmetros como peso, IMC, gorduras e parâmetros metabólicos. A eficácia é similar nos parâmetros antropométricos dos dois treinos físicos, concorrente e aeróbico.
Is oral hygiene performed by caregivers of children and adolescents with cerebral palsy effective?
Authors: Pacheco Valéria Marques Bordallo , Ferreira Ana Cristina Fernandes Maria , Ferreira Carolina de Andrade , Siqueira Vanessa Lira , Santos Maria Teresa Botti Rodrigues 
Published: November 2021

Objective: To evaluate the effectiveness of oral hygiene performed by caregivers of children and adolescents with cerebral palsy (CP) during the moments before and after three months of oral health instructions. Methods: In a longitudinal study, 102 participants were joined in two groups: G1 (n=51) composed of children and adolescents (C/A) with CP and G2 (n=51), composed of their caregivers. Sociodemographic and oral hygiene habits were collected and evaluated using the Visible Plaque Index (VPI) and Gingival Bleeding Index (GBI), before and after oral hygiene orientation. The Qui-Squared, ANOVA 1, and tStudent tests were applied. P < 0,05. Results: The C/A group with pattern clinical CP tetraparesis, diparesis and hemiparesis were homogeneous in terms of gender (P = 0,07), however differed in age (P < 0,05), the youngest being diparetic. No difference was observed when comparing VPI and GBI before and after instructions in oral health for the three clinical types (P> 0,05). However, a reduction in the VPI and GBI indexes (P < 0,05) before and after, in each of the three clinical patterns. Most of the caregivers were female, married, with a high school degree, and they performed oral hygiene three times per day. The caregivers presented significant drops in VPI and GBI after receiving oral hygiene instructions. (P < 0,05). Conclusion: Oral hygiene instruction is fundamental for the caregivers of children and adolescents with cerebral palsy since it is an effective form of controlling health problems.
Controle de qualidade de vinagres comercializados em Manaus
Authors: Souza Nistefanny Santana de , Pereira Layla Talissa Tundis , Souza Gabriel Oliveira de 
Published: November 2021

O vinagre caracteriza-se como uma solução diluída a base de ácido acético, estabelecida por dois processos: a fermentação alcoólica, quando o açúcar é modificado para etanol; e a oxidação fermentativa, convertendo o álcool em ácido acético. Com isso, ao longo da história, ele vem sendo usado como condimento e conservante de alimentos, além de ser constituído por propriedades nutritivas e biorregulatórias apontadas como complementos fundamentais na alimentação. O vinagre pode manifestar efeitos positivos fisiológicos relacionado com a regulação pressão arterial, controle da glicose sanguínea, auxílio na digestão e estimulação do apetite. O objetivo do estudo foi avaliar a qualidade de amostras de vinagres comercializados em Manaus. Foram selecionadas aleatoriamente 5 amostras de vinagres de diferentes marcas identificadas como amostras A, B, C, D, E, encontradas em estabelecimentos comerciais da cidade de Manaus-AM, no período de setembro a outubro de 2021. O teor de ácido acético nos vinagres foi quantificado seguindo metodologia adaptada de Baccan, 2001. O teor do ácido acético quantificado nos vinagres variou de 3,08% a 4,57%. As amostras C, D e E apresentaram valores de acidez abaixo do padrão estabelecido, os demais apresentaram valores de acidez de acordo com o que preconiza a legislaçãoa legislação vigente.
СПОГАДИ Ф. І. ЄЛІСЄЄВА – ДЖЕРЕЛО ВИВЧЕННЯ ВОЄННОГО МИСТЕЦТВА КУБАНСЬКОЇ КОЗАЦЬКОЇ КІННОТИ ПІД ЧАС АНТИБІЛЬШОВИЦЬКОГО ПОВСТАННЯ У КАВКАЗЬКОМУ ВІДДІЛІ ВЕСНОЮ 1918 р
Authors: Задунайський Вадим Васильович 
Published: November 2021

Під час повстання кубанських козаків проти більшовицького режиму в Кавказькому відділі весною 1918 р. важливу роль відіграла кавалерія. Дуже цінним джерелом для вивчення воєнного мистецтва козацької кавалерії під час цього повстання є мемуари талановитого козацького офіцера-кавалериста Ф. І. Єлісєєва (командував усією кавалерією повстанців). Воєнне мистецтво козацької кавалерії під час повстання мало сильні сторони: козаки дуже гарно вели кінний бій; вони могли діяти й у пішому строю; козаки застосували 20 стратегем (частково 1); якісно діяла козацька передова сторожа під час нічного наступу. Недоліки: не мали кінної артилерії; поразка основних сил повстанців призвела до деморалізації козаків-кавалеристів і їх дезертирства. Попри поразку, козацька кавалерія виявила високий рівень воєнного мистецтва.
БІЛОРУСЬКА СТРАТЕГІЧНА НАСТУПАЛЬНА ОПЕРАЦІЯ (23 ЧЕРВНЯ - 29 СЕРПНЯ 1944 РОКУ): ОРГАНІЗАЦІЯ ВЗАЄМОДІЇ ВІЙСЬК ЧОТИРЬОХ ФРОНТІВ
Authors: Кривизюк Леонід Петрович 
Published: November 2021

Аналізується Білоруська стратегічна наступальна операція: обстановка, що склалася на території Білорусії після бойових дій взимку і весною 1944 р.; загальні плани сторін на літньо-осінню кампанію; замисли командувачів фронтів на проведення фронтових операцій і завдання військам; питання взаємодії військ фронтів, загальновійськових армій, рухомих груп, артилерійських і авіаційних з’єднань в ході підготовки та проведення операції і зроблено висновки.
Economic and legal aspects of the use of computer programs
Authors: Borko Yuliia 
Published: November 2021

Keywords: computer program, economic and legal regulation, taxation, licenseagreement, initial cost, value added tax, royalties
The article deals with the economic and legal aspects of using computer programs inbusiness operations. In particular, certain problems of taxation relating to the creationand use of computer programs are considered. There have been consideredways and means of representations in the accounting of the following operations: purchaseof intellectual property rights to a computer program, supply of a computer programfrom a non-resident (resident) to a resident. The principles of the formation ofthe cost of a computer program, depending on the terms of purchase, have been outlined.The has been defined the concept of royalties from the use of a computer programin the economic activity of an enterprise. The article indicates that the supply ofservices (performance of work) related to software products and that introducechanges to the software are deemed to be any updates, changes, additions to expandtheir functionality. Such an operation is referred to as the supply of software productsusing IT benefits. The supply of services that do not introduce changes, namely: installation,configuration, testing, identification and rectification of deficiencies, information,and consulting support is referred to operations that are subject to VAT atthe general rate. The article states that VAT is charged on operations for the supplyof software products from a non-resident (resident) to a resident in the customs territory(customs territory) of Ukraine, which, in turn, is not subject to VAT. At the sametime, if as a result of the provision of technical support services for software products(including software products provided for use under the license agreement) there areno changes in software products (for example, training staff to work with the program,installing the program, configuration of office equipment, etc.), then operationsfor the provision of such services are subject to VAT in the generally established mannerin the amount of 20 percent.There has been determined the need to improve economic and legal regulation ofthe creation and use of computer programs in the economic activities of companies interms of taxation.
Construction of an Acetate Metabolic Pathway to Enhance Electron Generation of Engineered Shewanella oneidensis
Authors: Zhang Junqi , Chen Zheng , Liu Changjiang , Li Jianxun , An Xingjuan , Wu Deguang , Sun Xi , Zhang Baocai , Fu Longping , Li Feng , Song Hao 
Published: November 2021

Background: Microbial fuel cells (MFCs) are a novel bioelectrochemical devices that can use exoelectrogens as biocatalyst to convert various organic wastes into electricity. Among them, acetate, a major component of industrial biological wastewater and by-product of lignocellulose degradation, could release eight electrons per mole when completely degraded into CO2 and H2O, which has been identified as a promising carbon source and electron donor. However, Shewanella oneidensis MR-1, a famous facultative anaerobic exoelectrogens, only preferentially uses lactate as carbon source and electron donor and could hardly metabolize acetate in MFCs, which greatly limited Coulombic efficiency of MFCs and the capacity of bio-catalysis.Results: Here, to enable acetate as the sole carbon source and electron donor for electricity production in S. oneidensis, we successfully constructed three engineered S. oneidensis (named AceU1, AceU2, and AceU3) by assembling the succinyl-CoA:acetate CoA-transferase (SCACT) metabolism pathways, including acetate coenzyme A transferase encoded by ato1 and ato2 gene from G. sulfurreducens and citrate synthase encoded by the gltA gene from S. oneidensis, which could successfully utilize acetate as carbon source under anaerobic and aerobic conditions. Then, biochemical characterizations showed the engineered strain AceU3 generated a maximum power density of 8.3 ± 1.2 mW/m2 with acetate as the sole electron donor in MFCs. In addition, when further using lactate as the electron donor, the maximum power density obtained by AceU3 was 51.1 ± 3.1 mW/m2, which approximately 2.4-fold higher than that of wild type (WT). Besides, the Coulombic efficiency of AceU3 strain could reach 12.4% increased by 2.0-fold compared that of WT, which demonstrated that the engineered strain AceU3 can further utilize acetate as an electron donor to continuously generate electricity.Conclusion: In the present study, we first rationally designed S. oneidensis for enhancing the electron generation by using acetate as sole carbon source and electron donor. Based on synthetic biology strategies, modular assembly of acetate metabolic pathways could be further extended to other exoelectrogens to improve the Coulombic efficiency and broaden the spectrum of available carbon sources in MFCs for bioelectricity production.
Repurposing Combination Therapy of Voacamine With Vincristine for Downregulation of Hypoxia-Inducible Factor-1α/Fatty Acid Synthase Co-axis and Prolyl Hydroxylase-2 Activation in ER+ Mammary Neoplasia
Authors: Singh Lakhveer , Roy Subhadeep , Kumar Anurag , Rastogi Shubham , Kumar Dinesh , Ansari Mohd. Nazam , Saeedan Abdulaziz S. , Singh Manjari , Kaithwas Gaurav 
Published: November 2021

Graphical AbstractMechanism of VOA and VIN to inhibit fatty acid synthesis in DMBA-induced mammary gland carcinoma of albino Wistar rats. Hypoxia-activated HIF-1α enhances lactate acidosis in the tumor microenvironment, and dysregulated pH in the tumor microenvironment activates SREBP-1c and FASN expression to speed up the fatty acid synthesis required for plasma membrane synthesis in rapidly proliferating cells. VOA- and VIN-activated PHD-2 enhanced the proteolytic degradation of HIF, thus inhibiting fatty acid synthesis. HIF-1α, hypoxia-inducible factor-1α; SREBP-1c, sterol regulatory element-binding protein-1c; FASN, fatty acid synthesis; PHD-2, prolyl hydroxylase-2.
Association Between Serum Cystatin C and Thyroid Diseases: A Systematic Review and Meta-Analysis
Authors: Xin Caihong , Xie Jing , Fan Huaying , Sun Xin , Shi Bimin 
Published: November 2021

BackgroundCystatin C (CysC) is often used to diagnose and monitor renal diseases. Although some studies have investigated the association between serum CysC levels and thyroid diseases, their reported results were inconsistent. Therefore, the relationship between CysC levels and thyroid diseases remains controversial.AimThis meta-analysis aimed to statistically evaluate serum CysC levels in patients with thyroid diseases.MethodsA literature search was conducted using the PubMed, Web of Science, Embase, EBSCO, andWiley Online Librarydatabases. The following search terms were used for the title or abstract: “Cystatin C” or “CysC” in combination with the terms “thyroid disease”, “thyroid function”, “hypothyroidism”, or “hyperthyroidism”. The results of the systematic analysis were presented as standardized mean differences (SMDs) with corresponding 95% confidence intervals (CIs).ResultsEleven articles (1,265 cases and 894 controls) were included in the meta-analysis. The results of the meta-analysis showed that the serum CysC levels of patients with hyperthyroidism were significantly higher than those of the controls (SMD: 1.79, 95% CI [1.34, 2.25]), and the serum CysC levels of patients with hypothyroidism were significantly lower than those of the controls (SMD −0.59, 95% CI [−0.82, −0.36]). Moreover, the treatment of thyroid diseases significantly affected serum CysC levels.ConclusionsTo the best of our knowledge, this meta-analysis is the first to evaluate serum CysC levels in patients with thyroid diseases. Our findings suggest that thyroid function affects serum CysC levels and that serum CysC may be an effective marker for monitoring thyroid diseases.Systematic Review RegistrationPROSPERO [https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=258022], identifier CRD42021258022].