bluuebunny/crossref_metadata_2025_split huggingface dataset:
Responsabilité Sociétale de l’Entreprise et réponse sociétale : cas des PME tunisiennes
Authors: Turki Ahmed 
Published: November 2021

Après la révolution de janvier 2011, les PME tunisiennes sont sollicitées pour développer de nouvelles formes de réponses destinées à la société. L’objectif de cette recherche est d’analyser les réponses sociétales apportées par les PME tunisiennes ainsi que leur processus de développement. Afin d’atteindre cet objectif, une étude qualitative a été menée sur 10 PME. Les résultats montrent que les réponses sociétales sont essentiellement de nature sociale. Aussi, celles-ci sont développées en adoptant soit une approche tactique soit une approche stratégique. L’approche tactique s’oriente vers la manipulation des parties prenantes à travers la mise en place des actions sociétales sans négociation avec les parties concernées. Quant à l’approche stratégique, elle vise une mise en oeuvre conjointe des actions sociétales.
Accelerating Sulfur Redox Reactions by Topological Insulator Bi2Te3 for High‐Performance Li‐S Batteries
Authors: Song Xueqin , Tian Da , Qiu Yue , Sun Xun , Jiang Bo , Zhao Chenghao , Zhang Yu , Fan Lishuang , Zhang Naiqing 
Published: November 2021

AbstractPolysulfide shuttling and sluggish sulfur redox kinetics hinder the cyclability and rate capability of lithium‐sulfur (Li‐S) batteries. Accelerating sulfur redox reactions is considered a promising way toward the capture and utilization of soluble sulfur species. Herein, topological insulator (TI) Bi2Te3 is reported as an electrocatalyst for accelerated sulfur electrochemistry. The findings indicate that Bi2Te3 can effectively anchor soluble sulfur species and form seamless electron transport pathways with the adsorbed polysulfides. Both the sulfur reduction reactions and the reverse processes are found to be boosted by Bi2Te3. The incorporation of Bi2Te3 enables efficient operation of Li‐S batteries in terms of impressive rate capability of 857 mAh g−1 at 3 C and very low capacity decay of 0.033% per cycle over 1000 cycles. This work extends the application of TI to the field of Li‐S electrochemistry and may inspire further explorations.
Ultrahigh‐Performance Optoelectronic Skin Based on Intrinsically Stretchable Perovskite‐Polymer Heterojunction Transistors
Authors: Liu Kai , Bian Yangshuang , Kuang Junhua , Huang Xin , Li Yi , Shi Wei , Zhu Zhiheng , Liu Guocai , Qin Mingcong , Zhao Zhiyuan , Li Xifeng , Guo Yunlong , Liu Yunqi 
Published: November 2021

AbstractThe optoelectronic skin is acknowledged as the world's current cutting‐edge technology in the fields of wearable healthcare monitoring, soft robotics, artificial retinas, and so on. However, the difficulty in preparing stretchable photosensitive polymers and the high‐crystallization nature of most reported photosensitive materials (such as perovskites) severely restrict the development of skin‐like optoelectronic devices. Herein, a surface energy‐induced self‐assembly methodology is proposed to form easily transferrable and flexible perovskite quantum dot (PQD) films with a worm‐like morphology. Furthermore, intrinsically stretchable phototransistors (ISTPTs) are fabricated based on a stretchable photosensitive layer heterojunction consisting of worm‐like PQD films and hybrid polymer semiconductors. The obtained ISTPTs display highly sensitive response to high‐energy photons of X‐ray (with a detection limit of 79 nGy s−1, that is 560 times lower than commercial medical chest X‐ray diagnosis) and ultraviolet (with photosensitivity of 5 × 106 and detectable light intensity of 50 nW cm−2 among the highest performance of reported photodetectors). In addition, these ISTPTs demonstrate desirable e‐skin characteristics with high strain tolerance, high sensing specificity, high optical transparency, and good skin conformability. The surface energy‐induced self‐assembly methodology for the preparation of ISTPTs is a critical demonstration to enable low‐cost and high‐performance optoelectronic skins.
Mie Sensing with Neural Networks: Recognition of Nano‐Object Parameters, the Invisibility Point, and Restricted Models
Authors: Movsesyan Artur , Besteiro Lucas V. , Wang Zhiming , Govorov Alexander O. 
Published: November 2021

AbstractIn this work, artificial neural networks (ANNs) are used to recognize nano‐objects solely from the absorbance spectrum of a macroscopic sample. For this, ANNs with two recognition schemes are constructed. The first one is designed to recognize ensembles of dielectric scatterers. The second ANN model recognizes the dimensions of gold nanospheres in a mixture and the refractive index of a matrix. A challenge in the first scheme arises at and near the invisibility point, i.e., when the refractive index of nanoparticles is close to that of the medium. Of course, particle recognition in this regime faces fundamental physical limitations. However, such recognition near the invisibility point is possible, and this study reveals its unique properties. Interestingly, the recognition process for the refractive index in the vicinity of the invisibility point shows very small errors. In contrast, the errors for recognition of the radius grow strongly near this point. Another regime with limited recognition occurs when the extinction spectra are not unique and can correspond to different realizations of nanoparticle mixtures. The recognition schemes proposed and investigated herein can find their applications in sensing.
“Porous and Yet Dense” Electrodes for High‐Volumetric‐Performance Electrochemical Capacitors: Principles, Advances, and Challenges
Authors: Pan Zhenghui , Yang Jie , Kong Junhua , Loh Xian Jun , Wang John , Liu Zhaolin 
Published: November 2021

AbstractWith the ever‐rapid miniaturization of portable, wearable electronics and Internet of Things, the volumetric performance is becoming a much more pertinent figure‐of‐merit than the conventionally used gravimetric parameters to evaluate the charge‐storage capacity of electrochemical capacitors (ECs). Thus, it is essential to design the ECs that can store as much energy as possible within a limited space. As the most critical component in ECs, “porous and yet dense” electrodes with large ion‐accessible surface area and optimal packing density are crucial to realize desired high volumetric performance, which have demonstrated to be rather challenging. In this review, the principles and fundamentals of ECs are first observed, focusing on the key understandings of the different charge storage mechanisms in porous electrodes. The recent and latest advances in high‐volumetric‐performance ECs, developed by the rational design and fabrication of “porous and yet dense” electrodes are then examined. Particular emphasis of discussions then concentrates on the key factors impacting the volumetric performance of porous carbon‐based electrodes. Finally, the currently faced challenges, further perspectives and opportunities on those purposely engineered porous electrodes for high‐volumetric‐performance EC are presented, aiming at providing a set of guidelines for further design of the next‐generation energy storage devices.
Pyrazine‐interior‐embodied MOF‐74 for selective CO2 adsorption
Authors: Zhao Meng , Ban Yujie , Chang Ze , Zhou Yingwu , Yang Kun , Wang Yuecheng , Cao Na , Yang Weishen 
Published: November 2021

AbstractA series of pyrazine‐interior‐embodied metal–organic framework‐74 composites (py‐MOF‐74) were successfully synthesized by a post‐synthetic vapor modification method. Here, pyrazine molecules occupy the cavity to block the wide pores of MOF‐74, which accentuates the difference in adsorption of a pair of gases on MOFs and consequently reinforces the adsorption selectivity. Different from the “physical confinement” of occupants, the pyrazine molecule with dual “para‐nitrogen” atoms donates one N atom to bond with the open metal ion of MOF‐74 for stability and the other N atom for potential CO2 trapping. Typically, py‐MOF‐74c with the highest pyrazine insertion ratio displays selectivity greatly superior to that of MOF‐74 in equimolar CO2/CH4 (598 vs. 35) and in simulated CO2/N2 flue gas (471 vs. 49). Py‐MOF‐74 entities are long‐lived adsorbents, and their CO2 capacity can be maintained even after storage for 1 year in air. Py‐MOF‐74 also showed a sharp molecular sieve property in fixed‐bed cycle adsorption tests, which implies its great potential in real applications.
Extending the phenotype of DeSanto‐Shinawi syndrome: A case report and literature review
Authors: Ho Stephanie , Luk Ho‐Ming , Lo Ivan F. M. 
Published: November 2021

AbstractDeSanto‐Shinawi syndrome (DESSH, OMIM #616708) is a rare autosomal dominant neurodevelopmental disorder caused by loss‐of‐function variants in the WAC gene. Affected individuals are characterized by neonatal hypotonia, developmental delay, intellectual disability, behavioral problems, and dysmorphism. Epilepsy is present in some of the patients with DESSH. By far, less than 30 affected individuals have been reported worldwide. Herein, we report a 9‐year‐old Chinese girl with molecularly substantiated DESSH with a de novo nonsense c. 1648C>T p.(Arg550*) variant identified in the WAC gene. Aside from developmental delay and the characteristic facial gestalt, our proband also exhibited tethered cord syndrome due to filar lipoma and left duplex kidney complicated with hydronephrosis, features not observed in any of the previously reported individuals with DESSH.
Neurofibromatosis 1 in the setting of dual diagnosis: Diagnostic and management conundrums
Authors: Muthusamy Karthik , El‐Jabali Aseel , Ongie Laura J. , Dhamija Radhika , Babovic‐Vuksanovic Dusica 
Published: November 2021

AbstractNeurofibromatosis type 1 (NF1) is a common neurocutaneous disorder characterized by development of pigmentary skin changes, neurogenic tumors, and other manifestations involving multiple organ systems. Penetrance is complete, though expressivity is quite variable even among the family members. Given that NF1 is a common hereditary condition, existence of a second genetic disorder in NF1 patients is not unexpected. During comprehensive evaluations of individuals with NF1, we encountered 11 patients with dual diagnosis who contributed to phenotypic complexity and challenges for long‐term management. Examples include Prader–Willi Syndrome, Autosomal Dominant Polycystic Kidney Disease, Down syndrome, infantile myofibromatosis, Craniosynostosis, cleft lip and palate, 47,XYY, 22q11.2 duplication, 15q13.3 deletion syndrome, and BRCA2‐ and ATM‐ related cancer predisposition syndromes. Presence of dysmorphism, developmental delay, atypical tumors, and family history of other genetic disorders including cancers appears as determinants to consider a second genetic etiology and helps to differentiate from an extreme phenotypic spectrum of NF1. Clinicians should have high index of suspicion to exclude coexisting disorders, as apart from providing comprehensive medical care. This also has potential implications in genetic counseling. Long‐term effects of the synergistic mechanisms leading to phenotypic complexity and patient outcomes are yet to be characterized, with follow‐up needed.
Inhibition of lipid oxidation in mayonnaise by finger millet seed coat polyphenols
Authors: Velur Balasubramaniam Geetha , Sukumar Sathvika , Alagarsamy Meena , Velpandi Pon Sharmila Devi , Palaniappan Ayyappan , Roy Leema Mary , Antony Usha 
Published: November 2021

AbstractAuto‐oxidation of food emulsions leads to rancidity which significantly reduces the shelf life of the finished products. Polyphenols are potent antioxidants that can play a crucial role in inhibiting lipid oxidation. The effect of polyphenols derived from finger millet (Eleusine coracana v. GPU 28) seed coat (FMSC) on inhibiting auto‐oxidation in full‐fat mayonnaise was evaluated against a synthetic antioxidant (BHT). Mayonnaise samples with added FMSC polyphenols had higher overall acceptability with better texture (softer product). The viscosity of all samples decreased on storage. Enhanced lipid stability with FMSC polyphenols was evident from the low peroxide value of 5.523 ± 0.07 meq kg−1, acid value of 3.9 ± 0.25 mg KOH g−1, and thiobarbituric acid reactive species value of 0.41 ± 0.02 mg MDA kg−1, in comparison to mayonnaise treated with BHT (6.76 ± 0.08 meq kg−1, 4.2 ± 0.3 mg KOH g−1, and 0.51 ± 0.01 mg MDA kg−1) when stored for 7 weeks at 4°C. FMSC polyphenols are effective in inhibiting lipid oxidation in mayonnaise. The study is the first to report the potential of finger millet seed coat polyphenols as strong antioxidants on par with the synthetic BHT in retarding lipid oxidation. Considering the need for natural ingredients, the polyphenols from FMSC may be utilized in high‐fat products by the food industry in place of synthetic antioxidants.
Strongly structured populations and reproductive habitat fragmentation increase the vulnerability of the Mediterranean starry rayRaja asterias(Elasmobranchii, Rajidae)
Authors: Catalano Giusy , Crobe Valentina , Ferrari Alice , Baino Romano , Massi Daniela , Titone Antonino , Mancusi Cecilia , Serena Fabrizio , Cannas Rita , Carugati Laura , Hemida Farid , Manfredi Chiara , Melis Riccardo , Scarcella Giuseppe , Sion Letizia , Stagioni Marco , Tinti Fausto , Cariani Alessia 
Published: November 2021

AbstractThe Mediterranean starry ray (Raja asterias) populations within the Mediterranean Sea are susceptible to high rates of bycatch in the multispecies trawl fisheries. Understanding its population structure and identifying critical habitats are crucial for assessing species vulnerability and setting the groundwork for specific management measures to prevent population decline.To assess the population structure ofR. asteriasin the Mediterranean, the genetic variation in nine population samples at one mitochondrial marker and eight nuclear microsatellite loci was analysed. Moreover, 172 egg cases collected in the Strait of Sicily were identified at species level using integrated molecular and morphological approaches.Genetic analyses revealed that the Mediterranean starry ray comprises three distinct units inhabiting the western, the central‐western, and the central‐eastern areas of the Mediterranean. An admixture zone occurs in the Strait of Sicily and the Ionian Sea, where individuals of the central‐western and central‐eastern population units intermingle.The joint morphometric–genetic analyses of rajid egg cases confirmed the presence of more than one species in the admixture area, with a predominance of egg cases laid byR. asterias. DNA barcoding revealed that egg cases and embryos ofR. asteriasshared several haplotypes with adult individuals from the central‐western and central‐eastern Mediterranean Sea, revealing that females of both populations laid numerous eggs in this area.According to these findings, detailed taxonomic determination of egg cases, when combined with seasonal migration studies, could improve the capability to identify important spawning or nursery areas for the Mediterranean starry ray, particularly in those admixture zones relevant to maintaining genetic diversity.Finally, these new insights should be considered to update the Action Plan for the Conservation of Cartilaginous Fishes in the Mediterranean Sea with effective measures to reduce the impact of skate bycatch in trawling and safeguard egg cases in nursery areas.
Optical and UV properties of a radio‐loud and a radio‐quiet Population A quasar at high redshift
Authors: Deconto‐Machado Alice , del Olmo Ascensión , Marziani Paola , Perea Jaime , Stirpe Giovanna 
Published: November 2021

AbstractDifferent properties of quasars may be observed and analyzed through the many ranges of the electromagnetic spectrum. Pioneering studies showed that an “H‐R diagram” for quasars was needed to organize these data, and that more than two dimensions were necessary: a four‐dimensional Eigenvector (4DE1) parameter space was proposed. The 4DE1 makes use of independent observational properties obtained from the optical and UV emission lines, as well as from the soft‐X rays. The 4DE1 “optical plane,” also known as the quasar Main Sequence (MS), identifies different spectral types in order to describe a consistent picture of QSOs. In this work, we present a spectroscopic analysis focused on the comparison between two sources, one radio‐loud (PKS2000‐330, ) and one radio‐quiet (Q1410+096, ), both showing Population A quasar spectral properties. Optical spectra were observed in the infrared with VLT/ESO, and the additional measures in UV were obtained through the fitting of archive spectra. The analysis was performed through a nonlinear multicomponent decomposition of the emission line profiles. Results are shown in order to highlight the effects of the radio‐loudness on their emission line properties. The two quasars share similar optical spectroscopic properties and are very close on the MS classification while presenting significant differences on the UV data. Both sources show significant blueshifts in the UV lines but important differences in their UV general behavior. While the radio‐quiet source Q1410+096 shows a typical Pop A UV spectrum with similar intensities and shapes on both CIVλ1549 and SiIVλ1392, the UV spectrum of the strong radio‐loud PKS2000‐330 closely resembles the one of Population B of quasars.
Point‐of‐entry water filter for removal of per‐ and poly‐fluoroalkyl substances and precursors
Authors: Natarajan Manaswini , Dodds Suzanne , Allard Sebastien , Kaksonen Anna H. , Heitz Anna , Joll Cynthia A. 
Published: November 2021

AbstractTechnologies for per‐ and poly‐fluoroalkyl substances (PFAS) removal at a small scale suitable for point‐of‐entry (POE) treatment systems for household or business water supply are not well‐established. In the current study, a POE filter was tested for the removal of PFAS and precursors in groundwater contaminated with aqueous film‐forming foam. Long‐chain PFAS were more effectively removed than short‐chain PFAS. Total oxidizable precursor assays showed that precursors of short‐chain perfluoroalkyl carboxylic acids (PFCAs) broke through the filter earlier than routinely measured PFCAs and perfluoroalkyl sulfonic acids. The dissolved organic carbon removal trend was similar to that of PFAS and precursors. Overall, the POE filter achieved good long‐term removal (up to 7 months household equivalent) of the United States Environmental Protection Agency and Australian Drinking Water Guidelines‐regulated PFAS. This study provides benchmark data for the long‐term removal of precursors and PFAS using POE treatment systems for household or business water supply impacted by PFAS‐contaminated water.
Rapid cGMP manufacturing of COVID‐19 monoclonal antibody using stable CHO cell pools
Authors: Agostinetto Rita , Rossi Mara , Dawson Jessica , Lim Angela , Simoneau Mirva H. , Boucher Cyril , Valldorf Bernhard , Ross‐Gillespie Adin , Jardine Joseph G. , Sok Devin , Burton Dennis R. , Hassell Thomas , Broly Hervé , Palinsky Wolf , Dupraz Philippe , Feinberg Mark , Dey Antu K. 
Published: November 2021

AbstractTherapeutic proteins, including monoclonal antibodies, are typically manufactured using clonally derived, stable host cell lines, since consistent and predictable cell culture performance is highly desirable. However, selecting and preparing banks of stable clones takes considerable time, which inevitably extends overall development timelines for new therapeutics by delaying the start of subsequent activities, such as the scale‐up of manufacturing processes. In the context of the coronavirus disease 2019 (COVID‐19) pandemic, with its intense pressure for accelerated development strategies, we used a novel transposon‐based Leap‐In Transposase® system to rapidly generate high‐titer stable pools and then used them directly for large scale‐manufacturing of an anti‐severe acute respiratory syndrome coronavirus 2 monoclonal antibody under cGMP. We performed the safety testing of our non‐clonal cell bank, then used it to produce material at a 200L‐scale for preclinical safety studies and formulation development work, and thereafter at 2000L scale for supply of material for a Phase 1 clinical trial. Testing demonstrated the comparability of critical product qualities between the two scales and, more importantly, that our final clinical trial product met all pre‐set product quality specifications. The above expediated approach provided clinical trial material within 4.5 months, in comparison to 12–14 months for production of clinical trial material via the conventional approach.
Physical Characterization, Nutrient, Phenolic Profiles and Antioxidant Activities of 16 litchi Cultivars Grown in the Upper Yangtze River Region
Authors: Tan Si , Zhang Hongna , Chen Qin , Tang Yuxin , Yang Jiaqi , Zhang Xin , Li Wenfeng , Shi Shengyou 
Published: November 2021

AbstractLitchi grown in the upper Yangtze River region have the advantage of being late‐maturing owing to the geographical location. This study aimed to evaluate the physical characteristics, nutritional values, phenolic composition and antioxidant activities of 16 litchi cultivars grown in the upper Yangtze River region. Litchi grown in this region had total soluble solid and ascorbic acid contents comparable with those of cultivars grown in other locations. The total polyphenol contents were determined using the Folin‐Ciocalteu assay, and the phenolic profiles were determined using UPLC‐QqQ‐MS/MS. Nine phenolic compounds were identified and quantified in this study. Naringin, rutin and p‐coumaric acid were the major phenolic compounds in all the litchi cultivars. Statistical analysis of all the physiochemical results was performed using principal component analysis. Our results indicated that litchi grown in the upper Yangtze River region not only showed the late‐maturity characteristic but were also good dietary sources of phenolic compounds and antioxidants. In particular, ‘Fei Zi Xiao’ and ‘Jing Gang Hong Nuo’, characterized by high polyphenol contents and high antioxidant capacities, were of superior comprehensive quality. This study provides important information for the development of late‐maturing litchi industry.
The first presentation of Wolcott‐Rallison syndrome in a four‐month‐old infant with diabetic ketoacidosis (DKA) precipitating by COVID‐19: A case report
Authors: Maleki Elham , Baniasad Amir , Sepehran Mina , Davoudian Najmeh 
Published: November 2021

AbstractMonogenic diabetes mellitus (eg, Wolcott‐Rallison syndrome) is a rare condition. It associates with neonatal or early‐infancy insulin‐dependent diabetes. We reported DKA in the four‐month infant as the first presentation of monogenic diabetes that has accelerated by COVID‐19 infection. Therefore, considering the concurrency of COVID‐19 and DKA is crucial.
Perioperative management including dual cell salvage in a Jehovah's Witness patient undergoing major urological surgery
Authors: Smith Thomas G. , Anastasescu Irina , Wight James M. , Danaee Anicee , Nair Rajesh , O'Brien Tim S. 
Published: November 2021

AbstractComplex surgery associated with major hemorrhage presents particular risks for Jehovah's Witnesses who do not accept transfusion of blood products. Intraoperative use of two cell saver machines simultaneously can maximize the yield of salvaged blood from both the operative field and from washed surgical swabs and can potentially be life‐saving.