bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Prognostic Significance of the Histological Types in Patients With Nonsmall Cell Lung Cancer ≤2 cm
Authors: Hao Bo , Fan Tao , Xiong Juan , Zhang Lin , Lu Zilong , Liu Bohao , Meng Heng , He Ruyuan , Li Ning , Geng Qing 
Published: October 2021

Background: Few studies attempt to investigate the impact of histology on the outcome of nonsmall-cell lung cancer (NSCLC) patients. In this study, we aim to determine whether the type of histology influenced the outcome of stage IA NSCLC patients with tumor size (TS) ≤20 mm.Methods: The data of the population in our study was collected from the Surveillance, Epidemiology, and End Results (SEER) program, which is supported by the National Cancer Institute of the United States. The primary outcome was overall survival (OS). Cox-regression proportional hazards models were performed to identify prognostic factors for OS. The secondary outcome was lung cancer-specific mortality (LCSM). A competing risk model was used to identify risk factors associated with LCSM.Results: A total of 4,424 eligible patients (T1a-bN0M0) who received sublobar resection [wedge resection (WR) and segmentectomy] were identified and included in the study for further analysis. For patients with TS ≤ 10 mm, multivariate Cox-regression analyses for OS showed that lung squamous cell carcinoma (LUSC) yielded poorer OS compared with lung adenocarcinoma (LUAD), and no difference was observed between LUSC and LUAD for LCSM in competing risk models. For patients with TS &gt; 10 and ≤20 mm, multivariate analyses revealed that LUSC patients experienced poorer OS compared with that of LUAD; the univariate competing risk analysis indicated SCC pathology predicted an increased risk of death from lung cancer, whereas no difference is observed in the multivariate competing analysis. In addition, segmentectomy was associated with longer OS in patients with &gt;10 and ≤20 mm but not in patients with ≤10 mm compared with WR.Conclusion: Our study demonstrated that squamous pathology was associated with the worse OS but not LCSM for patients with ≤20 mm compared with adenocarcinoma. Moreover, segmentectomy when compared to wedge resection appears to be associated with a better prognosis in patients with neoplasm &gt;10 mm, but not in the case of nodule ≤10 mm.
Acceptance of a COVID-19 Vaccine Before it is Available in China During the Pandemic
Authors: Xu Jian , Liu Cong 
Published: October 2021

Objectives: China was believed to be the country with the world’s highest acceptance rate of the COVID-19 vaccine following several investigations. This study aims to explore the Chinese acceptance of a COVID-19 vaccine before it is made available, including its determinants.Methods: A cross-national online survey was conducted covering all 31 provinces of mainland China. The survey consists of the demographic variables, acceptance of a self-paid COVID-19 vaccine as the dependent variable, and the 3Cs factors (i.e., confidence, convenience, and complacency) as the independent variables.Results: Among the 1,532 participants, 57.9% accepted to get a self-paid COVID-19 vaccine. COVID-19 vaccine acceptors were more likely to be concerned about the effectiveness of the vaccines, believe that they were at risk of COVID-19 infection, have a high perceived susceptibility of COVID-19, and trust in the health care system.Conclusion: Findings indicate that the critical task in the early stage of the COVID-19 vaccine development in China is to increase the tolerance to some intuitive concerns about the vaccines, put more emphasis on the communication of the saliency of the disease threats, and effectively translate people’s trust in the government into vaccine acceptance.
Effect of Plastic Mulching on Soil Carbon and Nitrogen Cycling-Related Bacterial Community Structure and Function in a Dryland Spring Maize Field
Authors: Wang Sen , Ding Liuyi , Liu Wanyu , Wang Jun , Qian Yali 
Published: October 2021

Plastic mulching, given its positive effects on temperature and water retention, has been widely used to solve water shortages and nutrient scarcity in rainfed agricultural soils. This practice affects the physical and chemical processes of soil, including carbon and nitrogen cycling. However, research into microbe-mediated carbon and nitrogen cycling in soil with plastic mulching is still limited. In this study, the structures and functions of the soil bacterial community in non-mulched spring maize, plastic-mulched spring maize, and bareland fallow in a dryland field on the Loess Plateau in China were analyzed to explore the responses of microbe-mediated carbon and nitrogen cycling to plastic mulching. Results showed that the richness of soil bacteria was the highest in bareland fallow. Plastic mulching increased the diversity and richness of soil bacteria to a certain extent (p > 0.05), and significantly increased the content of microbial biomass nitrogen (MBN) (p < 0.05). Plastic mulching enhanced the total abundances of carbon and nitrogen cycling-related microbes, exhibiting a significant increase in the abundances of Cellvibrio, Bacillus, Methylobacterium and Nitrospira (p < 0.05). Predicted functional analysis revealed 299 metabolic pathways related to carbon and nitrogen cycling, including methane metabolism, carbon fixation in photosynthetic organisms, and nitrogen metabolism. The number of gene families assigned to carbon and nitrogen cycling-related metabolic pathways was higher in plastic mulched than that in non-mulched spring maize. This study demonstrated that plastic mulching enhances the capacity of carbon and nitrogen cycling, revealing its potential in mediating greenhouse gas emissions in the dryland spring maize fields on the Loess Plateau.
Struktur Komunitas Plankton di Perairan Kuala Gigeng, Provinsi Aceh
Authors: Agustiar Muhammad , Fazillah Muhammad Rizki , Sakinah Rauzatul , Razi Nanda Muhammad , Octavina Chitra 
Published: October 2021

Penelitian ini bertujuan untuk menentukan struktur komunitas plankton di Perairan Kuala Gigeng dari tahun 2017 sampai 2019. Penelitian ini menggunakan metode purposive sampling. Hasil penelitian menunjukkan bahwa terdapat 2 kelompok plankton yang ditemukan yaitu fitoplankton dan zooplankton. Kelompok fitoplankton terdiri dari kelas Bacillariophyceae dengan spesies yang ditemukan yaitu Rhizoselenia sp., Thalassiothrix longissima, dan Canccella sp., kelas Cyanophyceae terdiri dari spesies Planktotrix sp.. Sedangkan kelompok zooplankton termasuk kedalam kelas Copepoda yang terdiri dari spesies Alona sp., dan Cyclopoid sp.. Secara keseluruhan kelimpahan plankton berkisar antara 734,91 - 1364,83 ind/L. Indeks keanekaragaman plankton tergolong kedalam kategori rendah, keseragaman tergolong rendah dan dominansi tergolong ke dalam ketagori sedang.Kata kunci : Bioindikator, Fitoplankton, Kuala Gigeng, Struktur Komunitas, Zooplankton
CITY BRANDING SAIL TO INDONESIA 2019 DI PULAU BAWEAN SEBAGAI UPAYA MENINGKATKAN KUNJUNGAN WISATAWAN
Authors: Arfiyan Reza , Huda Anam Miftakhul 
Published: October 2021

Sail to Indonesia 2019 in Bawean Island is a program implemented by the Indonesian Ministry of Tourism in collaboration with yacht rally organizer from New Zealand. Sail to Indonesia has the purpose to develop tourism sector, especially maritime tourism in the area that is the path and center of Sail to Indonesia. Sail to Indonesia 2019, Yachters sailed in 10 places in Indonesia for three months, one of that in Bawean Island and Bawean Island became the only place in East Java which was visited by the Yachters. This research uses descriptive qualitative method that aims to analyze and determine the formation of the Sail to Indonesia 2019 image on Bawean Island as an effort to increase tourist visits. The results of this study concluded that the Department of Tourism & Culture of Gresik in forming the image of Bawean Island not only applied the theory of uniqueness of events according to Getz such as hospitality, symboliysm, authenticity, theming, and festive spirit, but also there is an element of convenience. Department of Tourism & Culture of Gresik did efforts to increasing tourist visits are by using wish images to maximize expectations of Bawean Island so as to provide the best service during activities. In addition, through the current image, tourists will tell all their best experiences and memories while on Bawean Island with word of mouth marketing.
Minor histocompatibility antigens as targets for T-cell immunotherapy
Authors: Pilunov A. M. , Romaniuk D. S. , Efimov G. A. , Savchenko V. G. 
Published: October 2021

Introduction. Minor histocompatibility antigens (MiHAs) — polymorphic peptides presented in HLA molecules that are products of genes containing nonsynonymous single nucleotide polymorphisms. In allogeneic hematopoietic stem cell transplantation (allo-HSCT), the immune response directed to MiHA can result both in graft-versus-host and graft-versus-tumor responses.Some MiHAs are promising and safe targets for T-cell immunotherapy of leukemia relapse after allo-HSCT.Aim — to analyze the literature describing the immune response to various MiHAs, as well as clinical trials using MiHAs as targets of immunotherapy.Main findings. MiHAs represent promising targets for the prevention or therapy of leukemia relapse after allo-HSCT due to their advantages over tumor-associated antigens and neoantigens. To be suitable for immunotherapy, MiHA must satisfy several parameters: 1) be presented by a common HLA allele, 2) have an optimal frequency of polymorphism-encoding allele, 3) be encoded by a gene that is predominantly expressed in hematopoietic tissue. This drastically limits the number of applicable targets and makes the discovery of new MiHAs highly relevant.
Hemophilia in the city of Novosibirsk and Novosibirsk region: Clinical phenotype, comorbidity
Authors: Babaeva T. N. , Sibirtseva V. N. , Yudanov A. V. , Shpagina L. A. , Khalzov K. V. , Shebunyaeva Y. Yu. , Melekhov S. P. , Pospelova T. I. 
Published: October 2021

Introduction. Despite the success of current therapeutic approaches and suffi cient supply of clotting factor concentrates, adult patients with hemophilia have a high frequency of developing joint pathologies. Furthermore, an increase in life expectancy has correlated with an increase in the share of patients with concomitant somatic diseases, which are characteristic for this population over the age of 40 years.Aim — to analyze the treatment results of adults with hemophilia living in the city of Novosibirsk and Novosibirsk region and evaluate their orthopedic status, types, frequency of bleeding, and comorbidity structure.Material and methods. A total of 93 patients were enrolled in the study (including 86 patients with hemophilia A and seven patents with hemophilia B). The analysis was carried out separately in subgroups of patients according to age: 18–24, 25–34, 45–44, and over 45 years old. Hemophilia type, severity of disease, strategy of therapy, inhibitor status, and features of concomitant pathology were analyzed.Results. A high frequency of spontaneous bleeding was found in all age groups of patients enrolled in the study (39.6 and 34.9 % during 6 and 12 months, respectively). The average frequency of joint bleeding was 4 cases per person per year in the group of patients aged ≥ 18 years.In evaluation of orthopedic status, it was remarkable that there was a signifi cant number of target joints (262, n = 93), which amounted to 2.8 defected joints per patient (the elbow, knee, and ankle joints were the most frequently involved in pathological process). All patients aged over 18 years with severe and moderate form of disease had a musculoskeletal complication with involvement of one or more target joints.The number of diseases per one patient prevailed in the age group over 45 years old and amounted to 4.12 comorbidities per patient. The prevalent diseases in the structure of concomitant pathology in adult patients with hemophilia were chronic viral hepatitis C (43.1 %, n = 42), stage I–III arterial hypertension (27.9 %, n = 26), stomach and duodenum diseases as well as gallbladder pathology (33.3 %, n = 31 and 26.9 %, n = 25, respectively), urolithiasis and chronic secondary pyelonephritis (21.5 %, n = 20).Conclusion. Despite the use of clotting factor concentrates in patients with severe and moderate hemophilia, the frequency of joint hemorrhages remains high, regardless of the age prophylactic replacement therapy was started. Additional measures must be taken to prevent the appearance of critical disease phenotype with frequent spontaneous bleeding.
Small Group Learning: Solusi Belajar pada Masa Pandemi
Authors: Farid Helmi Setyawan  
Published: October 2021

Pembelajaran melalui daring pada pandemi Covid-19 memiliki dampak negatif, salah satunya ialah penurunan kualitas pendidikan (learning loss). Salah satu upaya untuk menanggulangi learning loss dapat dilakukan dengan membuat kelompok belajar kecil di setiap daerah pada level RT dengan konsep Kampung Belajar. Penelitian ini bertujuan untuk mengetahui efektifitas penerapan Small Group Learning sebagai upaya mengatasi learning loss serta mengetahui perspektif peserta didik dan orangtua terhadap penerapan metode Small Group Learning ini. Penelitian ini merupakan deskriptif kualitatif dengan subjek penelitian adalah 100 peserta didik tingkat SMP. Teknik pengumpulan data menggunakan observasi, wawancara dan dokumentasi. Teknik analisis data menggunakan reduksi data atau penyederhanaan data, penyajian data, Penarikan Kesimpulan atau verifikasi. Pemeriksaan keabsahan data menggunakan triangulasi teknik dan triangulasi sumber. Pemeriksaan keabsahan data menggunakan triangulasi teknik dengan menggunakan tiga teknik pengumpulan data yaitu observasi, wawancara dan dokumentasi. Pemeriksaan keabsahan data menggunakan triangulasi sumber yaitu dengan menggunakan sumber data yang berasal dari guru. Berdasarkan hasil penelitian dapat disimpulkan bahwa penerapan metode Small Group Learning dengan konsep Kampung Belajar dinyatakan efektif dan mampu memberikan solusi terhadap learning loss yang dihadapi peserta didik serta mampu meningkatkan motivasi belajar peserta didik.
To the question of the methodology of the study of visual sources (on the example of ethnic marked plots of Soviet cartoons)
Authors: Шевцова А.А. , Гринько И.А. 
Published: October 2021

авторы, уже обращавшиеся к различным сюжетам через призму советской визуальной сатиры, предлагают собственную методологию исследования карикатуры. Рассматривая ключевые паттерны этносюжетов в динамике и фигуры умолчания советской визуальной сатиры, формирующиеся базовые и визиотипы, статистику появления различных этнических образов и ее связь с этнополитическим контекстом, можно выявить корни современных этнических стереотипов, рожденных в том числе советским визуальным языком.
the authors, who have already addressed various subjects through the prism of Soviet visual satire, offer their own methodology for the study of caricature. Considering the key patterns of ethnic plots in dynamics and figures of silence of Soviet visual satire, the emerging basic and visiotypes, the statistics of the appearance of various ethnic images and its connection with the ethnopolitical context, it is possible to identify the roots of modern ethnic stereotypes, including those born of the Soviet visual language.
Learning environment as a sociocultural phenomenon
Authors: Митницкая Е.В. 
Published: October 2021

в статье рассматривается понятие «образовательная среда» и обосновывается тот факт, что образовательная среда является подсистемой социокультурной среды и таким образом формирует часть социокультурного пространства. Автор приходит к выводу, что современная образовательная среда –необходимое условие становления современного человека, предоставляющее возможность каждому обучающемуся развить свой творческий потенциал. Особое внимание уделяется тому, что образовательная среда формируется исторически и является неотъемлемой частью культуры общества.
the article deals with the concept of "learning environment" and presents an argument that the learning environment acts as a subsystem of socio-cultural environment and thus forms part of the socio-cultural field. The author comes to the point that contemporary learning environment is an indispensable prerequisite for the formation of a modern personality and provides an opportunity for each student to enlarge their creative scope. Special attention is paid to the fact that learning environment is an integral component of any culture and thus is formed historically.
Human capital for the social protection sector in Africa: problems and opportunities
Authors: Миняжев Т.Р. , Мусеве О.Х. 
Published: October 2021

в статье рассматриваются особенности и проблемы кадрового обеспечения системы социальной защиты в развивающихся странах Субсахарской Африки. Показано, как на развитие человеческих ресурсов социальной защиты влияют недостаточность финансирования, социально-демографическая структура, неразвитость системы среднего и высшего образования, специфика урабанизационных процессов и рынка труда, высокая конфликтность. Определены основные возможности кадрового обеспечения для институционального развития социальной защиты в Африке.
the study analyses features and problems of the social protection sector in Sub-Saharan Africa related to human resources (HR). The sector’s HR are influenced by the lack of financial resources, demographic structure, underdevelopment of secondary and tertiary education, specific labor market and urbanization, intense conflicts, and violence. The study points to key opportunities and directions for HR development in the sector.
Legal education of children left without parental care. Historical and legal research
Authors: Цветцих И.Э. 
Published: October 2021

автор анализирует правовое образование детей, оставшихся без попечения родителей, через правое воспитание и правовое обучение в историко-правовом аспекте. Выделены проблемы правового образования в современной России.
the author analyzes the legal education of children left without parental care, researches through legal upbringing and legal teaching in the historical and legal aspect. The problems of legal education in modern Russia are highlighted.
Digital transformation of the knowledge economy in the context of integration processes in the world economy
Authors: Тинькова Е.В. 
Published: October 2021

в статье рассмотрены основные направления и проблемы цифровой трансформации знаний в условиях интеграционных процессов в мировой экономике, показана роль цифровизации в ускорении процессов возникновения, передачи и приобретения знаний в глобальном мировом пространстве. Выявлена роль перехода от аналоговой формы представления информации и знаний к цифровой.
the article considers the main directions and problems of digital transformation of knowledge in the context of integration processes in the world economy, shows the role of digitalization in accelerating the processes of the emergence, transfer, and acquisition of knowledge in the global world space. The role of the transition from the analog form of information and knowledge representation to the digital one is revealed.
Chronicle of Inculcation the Educational Programs in Palestinian Schools in the Second Half of the 20th Century
Authors: Абуджрай Абдалла 
Published: October 2021

цель автора – представить историю школьного образования в Палестине во второй половине ХХ в., рассказать о статусе школьников и условиях приема в школу на новый учебный год. Школьное образование в Палестине прошло несколько этапов в 1950–1960-х гг. до прихода к власти Палестинской национальной администрации. С началом первого палестинского восстания (1987–1991) условия вновь изменились. Географическое расхождение между сектором Газа и Западным берегом повлияло и на то, что их школьные программы полностью отличаются. С созданием Палестинской автономии в 1993 г. ее первой миссией было внедрение всеобщего образования в секторе Газа и на Западном берегу. В исследовании применен метод интервьюирования и анализ основных программных документов.
the purpose of this article is to present the historical facts of school education in Palestine in the second half of the twentieth century, as well as indicate the status of schoolchildren and the conditions for admission to school for the new academic year. School education went through several stages in the 1950s and 1960s until the Palestinian National Authority came to power. With the outbreak of the first Palestinian uprising from 1987 to 1991 conditions changed again. The geographic discrepancy between the Gaza Strip and the West Bank also contributed to their complete divergence in school curricula. With the creation of the Palestinian Authority in 1993, its first mission was to promote universal education in the Gaza Strip and the West Bank. The study used the interviewing method and analysis of the main program documents.
Management of the processes of development of subjective qualities of the individual in the conditions of mixed learning
Authors: Ярулов А.А. 
Published: October 2021

в статье рассматриваются основные ориентиры психолого-педагогического содействия развитию субъектных качеств личности в условиях смешанного обучения.
the article deals with the main guidelines of psychological and pedagogical assistance to the development of subjective qualities of the individual in the conditions of mixed learning.
Model of corporate culture of an educational organization: levels, subjects, interactions
Authors: Купцова И.А. 
Published: October 2021

в статье представлена многоуровневая модель корпоративной культуры образовательной организации, включающая такие структурные элементы, как субъекты образовательной деятельности (обучающиеся, обучающие, администрация, вспомогательный персонал); элементы фирменного стиля, внешняя атрибутика корпоративной культуры (логотип, гимн, эмблема, герб, символика); стиль и нормы поведения; традиции как неотъемлемый элемент корпоративной культуры образовательной организации; миссия образовательной организации; «третья миссия» и ее трактовка и понимание субъектами образовательной деятельности; социальные взаимодействия и волонтерство различных видов; корпоративное обучение и система повышения квалификации. Все эти компоненты многоуровневой системы корпоративной культуры проявляется на формальном и неформальном уровне, имея одновременную направленность как вовне, так и непосредственно включенные во внутреннюю жизнь образовательной организации.
the paper presents a multilevel model of corporate culture of educational organization, which includes such structural elements as: subjects of educational activity (students, trainees, administration, support staff); elements of corporate style, external attributes of corporate culture (logo, anthem, emblem, coat of arms, symbols); style and behavior standards; traditions as an integral element of corporate culture of educational organization; mission of educational organization; "the third mission" and its interpretation and understanding sub All these components of multilevel system of corporate culture are manifested at the formal and informal level, having simultaneous orientation both outside and directly included in the internal life of the educational organization.
Strategic resources of a post-industrial society
Authors: Заякина И.А. , Демина В.В. 
Published: October 2021

с развитием постиндустриального общества, становлением новых технологических укладов, связанных с формированием и использованием компьютерных средств хранения, накопления и передачи информации и знаний, осуществилась возможность модернизации способов хозяйствования за счет использования информации как приоритетного ресурса. В статье анализируются стратегические ресурсы, необходимые для эффективного развития в постиндустриальном обществе.
with the development of post-industrial society, the formation of new technological structures associated with the formation and use of computer means of storing, accumulating, and transmitting information and knowledge, the possibility of modernizing the ways of managing using information as a priority resource has been realized. The article substantiates the strategic resources necessary for effective
development in a post-industrial society.