bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation regarding the presence of Trypanosoma cruzi in triatomines and humans in rural households in the State of Paraná, southern Brazil
Authors: Abreu Ana Paula de , Silva Hevillyn Fernanda Lucas da , Sarto Marcella Paula Mansano , Iunklaus Giullia Ferreira , Trovo João Vitor , Fernandes Nilma de Souza , Sá Amanda Regina Nichi de , Gomes Mônica Lucia , Toledo Max Jean de Ornelas 
Published: August 2021

Trypanosoma cruzi, the etiologic agent of Chagas disease (CD), is transmitted by hematophagous insects belonging to the subfamily Triatominae. After elimination of Triatoma infestans, the infestation of human dwellings by secondary species of vectors continues to pose a risk of transmission of the parasite. Our aim was to investigate the T. cruzi presence in triatomines and humans in rural households in the State of Paraná, southern Brazil. The capture of the insects was carried out by technicians of the municipalities after residents reported the outbreak. Five residents and 27 triatomines captured in four municipalities in the North and Midwest of the state were evaluated. The research of T. cruzi was carried out using parasitological, serological, and molecular techniques, in human blood, excreta, intestinal contents and insect macerate. Panstrongylus megistus, P. geniculatus and Triatoma sp. were identified. Ten specimens of P. megistus were captured in a house in Mandaguari with five residents and presented an infection rate of 70% for T. cruzi like. All residents tested negative for T. cruzi infection. Another 15 P. megistus were captured in the peridomicile in Janiópolis and had 100.0% positivity. The only adult specimen of P. geniculatus captured in the intradomicile in Amaporã, as well as the nymph of Triatoma in the peridomicile in Paiçandu, were negative. The finding of P. megistus naturally infected by T. cruzi in households in rural area of Paraná demonstrates a potential risk of vector transmission of CD in these regions.
Hope and attitudes related to suicidal behavior among nursing students
Authors: Chiarelo Bruna Marques , Silva Amanda Heloisa Santana da , Silva Isabelle Wengler , Zanetti Ana Carolina Guidorizzi , Andrade Maria Betânia Tinti de , Vedana Kelly Graziani Giacchero 
Published: August 2021

Objective: to investigate, among nursing undergraduate students, the predictors of hope, suicidal thoughts and attitudes related to suicidal behavior. Methodology: Cross-sectional study, with a quantitative approach, developed in 2018 with 337 undergraduates from a Brazilian public university. We applied a sociodemographic, clinical and psychosocial questionnaire; the Suicide Behavior Attitude Questionnaire and the Herth Hope Scale. We used mean comparison tests, Pearson’s correlation test and binary logistic regression. Results: Predictors of hopelessness were psychiatric diagnoses, mental health treatment, absence of religious beliefs and dissatisfaction with the received social support. The chances of suicidal thoughts were higher among people with psychiatric diagnoses, dissatisfaction with the received social support, more understanding of the right to suicide and hopelessness. Predictors of more negative feelings about suicidal behavior were less professional competence and non participation in scientific events. Older students and those with less suicidal thoughts increased the chances of condemnatory attitudes. Predictors of fewer self-perceived competence were negative feelings about suicidal behavior, dissatisfaction with social support and less educational exposure (previous reading of suicide prevention materials or participation in events) and not having friends/relatives at suicide risk. Conclusion: it is important to develop and evaluate undergraduate support and educational strategies that consider the factors investigated in this study, in order to promote hope and training for suicide prevention.
Antimicrobial and cytotoxic activity of fungal mycelial extracts from aquatic environments in the Amazon
Authors: Oliveira Marta Rodrigues de , Santiago Sarah Raquel Silveira da Silva , Katak Ricardo de Melo , Camargo Marlene Rodrigues Marcelino , Bastos Ivanildes dos Santos , Orlandi Patrícia Puccinelli , Tadei Wanderli Pedro , Souza Afonso Duarte Leão de , Souza Antonia Queiroz Lima de 
Published: August 2021

Fungi are a prolific source of biologically active metabolites, including a wide range of clinically important drugs. Therefore, this study aims to evaluate the antimicrobial and cytotoxic activity of secondary metabolites extracted from fungal mycelia isolated from freshwater samples in the state of Amazonas. Mycelial extracts from 12 fungal were used, extracted with MeOH/AcOEt (1:1) according to the criteria established by Souza et al. (2004). For antimicrobial activity, the extracts were tested against the pathogens Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Enterococcus feacalis, Candida albicans and C. tropicalis. To identify the minimum inhibitory dosage (MID) the microdilution method was used. To perform the cytotoxicity assay, the VERO strain (ATCC® CCL-81TM) was used. The assays were determined by the Alamar Blue method according to Ahmed et al. (1994). The tested extracts did not show antibacterial activity. Five extracts (41.7%), obtained from the fungi Aspergillus - 1283, Chrysoporther - 1169, Diaporther – 1203, Fusarium – 1085, and Trichoderma, showed antifungal activity against C. albicans. Diaporther extract (8.3%) - 1203 was active against C. tropicalis. In the cytotoxicity assay, 58.3% of the evaluated extracts showed no significant toxic effect. Five extracts, Cladosporium - 1135, Chrysoporther - 1169, Cytospora - 1098, Fusarium - 1085, and Talaromyces - 1244, showed cytotoxic potential, exhibiting viability lower than 70%. The results obtained suggest that mycelial extracts of fungi isolated from water samples from the Amazon region have potential against yeasts of medical interest. Only two of the active extracts were revealed potentially cytotoxic.
Evaluation of the position of lingula mandible, mental foramen and lingual foramen of individuals in the 7-17 age groups via Cone-Beam Computed Tomography
Authors: GÖLLER BULUT Duygu , BAYRAK Seval 
Published: August 2021

Objective: The identification of landmarks in mandible is an important stage before dental procedures ın pediatric patients. The purpose of this study was to determine the location of lingula mandible, mental foramen (MF) and lingual foramen (LF) in a paediatric population.
Methods: The distance of lingula mandible to the anterior, posterior, superior, and inferior borders of mandible and to distal edge of the alveolar socket of the 1st molar tooth were measured. MF and LF distance to the top of the alveolar crest and the inferior edge of the basis mandibulae were determined. The horizontal location of MF was evaluated.
Results: The distance between lingula mandible and the sigmoid notch, the inferior border of the ramus, the anterior border of the ramus and the posterior border of the ramus was 18.63±4.52 mm, 24.81 ± 5.19 mm 14.67±2.39 mm, and 15.14 ± 3.06 mm respectively. The MF was mostly located between long axes of first and second premolar teeth. LF is closer to the inferior edge of the basis mandibulae.
Conclusion: It is necessary to determine anatomical landmarks in children prior to the surgical operations to prevent the possible neurovascular complications.
The Relationship between Health-Promoting Lifestyle Behaviors and Sleep Quality of Nurses Working in the Pediatrics Clinics:
Authors: ÇALIKUŞU İNCEKAR Müjde , BALCI Serap , VURANKAYA Esra , TUNCEL Beyza , ZOR Ebru 
Published: August 2021

Objective: The study was conducted to determine the relationship between health-promoting lifestyle behaviors and sleep quality of nurses working in the pediatrics clinics.
Methods: The study was conducted among nurses working in the pediatrics clinic of a training and research hospital located in X. Nurse Information Form, Health-Promoting Lifestyle Profile-II (HPLP-II), and Pittsburg Sleep Quality Index (PSQI) were applied to the nurses. Besides the descriptive statistics, Mann Whitney U test, Kruskal Wallis test, and Spearman’s Rho Correlation analysis were used for the analysis of the study.
Results: Among the 200 nurses that were surveyed, 121 (60.5%) responded. 81% of the nurses (n=98) were female, 19% (n=23) were male, and 80.2% had a bachelor’s degree. Age average of the nurses was 25.74±3.86 years and the average weekly working hours was 49.40±7.70 hours. It was determined that total mean score of HPLP-II was 125.26±16.40 and PSQI total mean score was 12.13±2.29. The lowest mean HPLP-II subscale score was 16.19±4.64 for exercise and 17.71±3.74 for stress management. A statistically significant correlation was found between the HPLP-II total scores and PSQI total scores (r= - 0.19; p< 0.05).
Conclusion: It was determined that the health-promoting lifestyle behaviors of the nurses were above the moderate level, their sleep quality was poor, and there was a significant correlation between the health-promoting lifestyle behaviors and the sleep quality of the nurses. It can be suggested by nursing to conduct the studies determining the practices that will improve the health-promoting lifestyle behaviors of the nurses and enhance their sleep quality.
Traditional practices performed by nurses during postpartum period
Authors: AYGÖR Hamide , DURDURAN Yasemin , EGE Emel 
Published: August 2021

Objective: In order to provide a quality health service, the awareness of traditional practices of healthcare providers, especially nurses, is as important as the understanding of the illnesses and health perception of those receiving care and their approaches to contemporary and traditional practices, because nurses' own cultural values and beliefs can affect their decisions and attitudes toward the patients. .
Methods: This descriptive study was performed with female nurses with children and working in a university hospital. The sample was not determined by using any special method of selection. The study was completed with the participation of 316 nurses who volunteered to participate in the study. The participation rate was 82%. Data were collected from October 2018 to April 2019 by using a survey form developed by the researchers based on the literature
Results: Of the nurses, 91.5% thought traditional practices were important but 8.5% thought that such practices were unimportant to prevent/resolve health-related problems. The most common first three practices that the nurses implemented to prevent puerperal fever included fortieth-day baths (44.3%), praying (37.3%), and not staying home alone (28.2%). Conclusion: It is important for nurses to be aware of their viewpoints against traditional practices as to understanding transcultural care and providing service in this direction
Breastfeeding in Turkey: A Systematic Review
Authors: YILMAZ Tülay , DİNÇ Hüsniye , GÜNAYDIN Sevil , KAÇAR Nükhet 
Published: August 2021

Objective: This study was carried out to systematically review the studies conducted on breastfeeding in Turkey and to provide information on
the breastfeeding status.
Methods: This study is a systematic review and conducted by examining 47 studies carried out in Turkey between January 2008-December 2018 and published in national and international journals. The methodological quality of the studies was examined according to the evaluation criteria of the Joanna Briggs Institute Critical Appraisal Checklist for Studies Reporting Prevalence Data. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist was used while reporting the review.
Results: According to the obtained study results, it was determined that the time of breastfeeding initiation and the mean duration of breastfeeding were in quite a wide range. Among breastfeeding-related factors, maternal age, education, employment status, the number of living children, the type of birth, preterm birth, receiving professional support on breastfeeding, early postnatal breastfeeding, and giving complementary feeding or formula were frequently listed. The most common reason for starting complementary feeding or was determined to be the idea that breast milk was insufficient.
Conclusion: No common language and unity of definition were observed in the studies reviewed. The studies were conducted in different samples. It is thought that the systematization of studies on breastfeeding will be scientifically useful for determining the current situation, determining the scope of future studies, and making the necessary arrangements.
Microleakage and Marginal Integrity of Direct and Indirect Composite Resin Restorations in MOD Cavities After Thermo-Mechanical Loading
Authors: ŞENOL Ayşe Aslı , YILMAZ ATALI Pınar , KAHRAMANOĞLU Erkut 
Published: August 2021

Objective: The aim of this in vitro study is to compare the microleakage of mesial-occlusal-distal (MOD) composite resin restorations made by using CAD/CAM block and methacrylate/ormocer-based direct resin composites after thermo-mechanical loading.
Methods: Standard 40 noncarious human third mandibular molars were selected for the study. Standardized MOD (3x4x2mm) cavities were prepared on the mesial and distal sides. The gingival margin was placed above the cementoenamel junction (CEJ) on the mesial side and below the CEJ on the distal side. The prepared samples were divided into three experimental groups [indirect group-GrandioBlock (GB), direct-methacrylate group-TetricN-Ceram+TetricN-Flow (T+TF), direct-ormocer group-Admira Fusion+Admira Fusion Flow (A+AF)] and control group [direct-methacrylate group-GrandioSo+GrandioSoFlow (G+GF)] (n=10). After finishing restorations samples were subjected to 50 N to 240.000 thermo-mechanical cycles (5-55°C, for 60 sec) and kept in 0.2% methylene blue. Samples sectioned longitudinally in the mesiodistal direction with a precision cutting device were examined under stereomicroscope at X8 and X25 and microleakage values were scored. In the evaluation of the data, descriptive statistical methods as well as the chi-square test was used for the comparison of qualitative data.
Results: No significant difference was found among the coronal and gingival-enamel microleakage distributions of the groups (p>0.05). A statistically significant difference was observed among the gingival-cementum microleakage distributions of the groups (p=0.003). The distribution of gingival-cement microleakage with the no dye penetration score in the T+TF group was found to be statistically significantly lower than the G+GF and GB groups (p = 0.010, p = 0.001).
Conclusion: Under the limitation of this in vitro study; restoring MOD cavities using different matrix structures of the composites could not eliminate the leakage at the gingival seat under CEJ.
Preclinical Medical Students’ Awareness About Disabled Friendly Campus
Authors: DAVUN Selin , KURNAZ AY Merve , KARAVUŞ Melda , KİLVAN Fatma , KURALAY İrem , AKBAĞRA Burçe , AKALIN Onur , HIDIROĞLU Seyhan 
Published: August 2021

Objective: The "Disabled Friendly Campus" is relatively new consept in the world. In this study we aimed to evaluate the awareness of preclinical medical students about the Disabled Friendly Campus.
Methods: Cross-sectional study was conducted at a public university’s Faculty of Medicine Campus. In our study, 362 students were included and the data were obtained between March and June 2019. A questionnaire was prepared in the light of the literature. In the first part of the questionnaire, socio-demographic features were questioned; In the second part of the questionnaire there were 13 questions about the arrangements required for a disabled person on a campus. Answer options such as 1= I don't agree, 2= I have no idea and 3= I agree. The score varied between 13-39, and as the total score obtained increases, it was assumed that the awareness of Disabled Friendly Campus will increase.
Results: In our study 3.3% (n = 12) of the participants had any disability, and 18.2% (n = 66) had a disabled person in their family. A statistically significant difference was observed between the participants' disabled friendly campus awareness scores according to their gender, class, their participation in an activity related to disabled people and whether they found their campuses suitable for disabled people.
Conclusion: It can be suggested that the questionnaire, which is assumed to evaluate the awareness of preclinical medical students on Disabled Friendly Campus, can be made into a scale with high validity and reliability.
Characteristics and Coronavirus Anxiety Levels of Endodontic Patients During the Covid-19 Pandemic
Authors: DURMAZPINAR Parla Meva , SEZGİN Güzide 
Published: August 2021

Objective: The aim of this study was to determine the characteristics and coronavirus anxiety levels of patients who applied to an endodontics clinic in Turkey during the Covid-19 pandemic.
Methods: A total of 212 patients who applied to an endodontics clinic between January 1 and 31 2021, were asked to complete a questionnaire that included demographic information, Covid-19 history, anxiety history, and coronavirus anxiety scores. After the patients were examined by an endodontist, their complaint, pain level—using the Verbal Numerical Rating Scale (VNRS)—clinical findings, periapical index score (PAI), and endodontic diagnosis were recorded.
Results: About half of the patients (43.4%) were diagnosed with symptomatic irreversible pulpitis. The mean of the VNRS was 4.17 ± 3.14 with a median of 4. Approximately 43% of the patients’ PAI scores were 1, which radiologically indicates normal periapical structures. When patients’ coronavirus anxiety scores were evaluated, 86.8% were categorized as non-disordered and 13.2% as disordered.
Conclusion: Patients tended to visit an endodontics clinic usually for urgent procedures and postponed other dental procedures due to anxiety related to the Covid-19 pandemic in Turkey.
CBCT Visualization of Furcation Perforation Repair Materials Using Different Voxel Sizes
Authors: ORHAN Ayse Isıl , TUFENKCİ Pelin , ONCU Aysenur , SEVGI Sevinc , CELİKTEN Berkan , ORHAN Kaan 
Published: August 2021

Background: Three-dimensional cone-beam computed tomography is gaining popularity as an imaging modality aiding the performance of difficult endodontic treatment procedures. For this reason, we assessed the visualization of bioactive furcal perforation repair materials in an ex vivo study using CBCT with different voxel sizes and determined which voxel size yielding the best images with least artefacts. Visualization of endodontic restorative material is affected by the appearance of various artifacts. This study was conducted to evaluate the CBCT visualization of three perforation repair materials using five different voxel sizes.
Methods: This study was performed with 84 mandibular molars that had been extracted for various reasons. All samples were measured with a digital caliper (Digimess, São Paulo, Brazil), marked at 3 mm above the cementoenamel junction, and decoronized at this line. The root segments were amputated at 3 mm below the furcation site using diamond discs under water cooling. Endodontic access cavities were then created, and the perforations were formed. Biodentine, MTA, and EndoSequence were mixed following the manufacturers’ instructions and applied to the perforation sites. Five image sets were obtained: 0.075 mm3; 0.1 mm3; 0.15 mm3; 0.2 mm3; and 0.4 mm3. Each scan was evaluated by 2 observers with 8 to 12 years of experience in CBCT imaging.
Results: The best image quality for repair all materials was achieved with a voxel size of 0.1 mm3. Image clarity of repair materials was no statistically difference between voxel sizes of 0.075 mm3 and 0.15 mm3. Image quality was significantly reduced at voxel sizes of 0.2 mm3 and 0.4 mm3, and was the worst quality at 0.4 mm3 voxels in all groups.
Conclusions: CBCT imaging can be used to examine endodontic repair materials with adjustment of the effective radiation dose rate and selection of the appropriate voxel size.
Frecuencias genotípicas en Niños con Leucemia Linfoblástica Aguda en dos centros Oncológicos.
Authors: Murillo Guamán Johanna Andrea , Ochoa Castro Maritza Raphaela , Zaruma Torres Fausto Leandro 
Published: August 2021

Introducción: La leucemia linfoblástica aguda (LLA) es una de las oncopatologías más frecuentes a nivel infantil, ocupando el primer lugar de los cincos tipos de cáncer con mayor incidencia en Ecuador. El objetivo del estudio fue determinar las frecuencias genotípicas y alélicas de los polimorfismos genéticos de MTHFR 677C>T (rs1801133) y MTHFR 1298A>C (rs1801131) en niños con leucemia linfoblástica aguda de SOLCA – Loja y SOLCA –Cuenca.
Métodos: Es un estudio transversal, donde se evaluó a 160 pacientes pediátricos diagnosticados con LLA. La detección de los polimorfismos MTHFR 677C>T y 1298A>C se realizó mediante la técnica PCR en tiempo real. El análisis estadístico descriptivo se desarrolló a través del software IBM SPSS (versión 22) y el programa bioinformático SNPStats.
Resultados: Se determinó que las frecuencias genotípicas para el SNP MTHFR 677C>T fueron 25% C/C y 75% C/T con una frecuencia alélica del 38% para el alelo mutado (T). Para el SNP MTHFR 1298 A>C se encontró una frecuencia genotípica de 2% A/A, 16% A/C y 82% C/C, en tanto que su frecuencia alélica fue del 90% para el alelo mutado (C). No se encontró asociación genotípica ni alélica con ninguna de las variables intervinientes (p>0.05), así como tampoco se manifestó una correlación estadísticamente significativa de los polimorfismos en mención y el tipo de riesgo de LLA.
Conclusión: En la población estudiada con LLA, se evidenció para el SNP de MTHFR 677C>T una frecuencia genotípica del 75% para el heterocigoto C/T. Para el SNP MTHFR 1298A>C se encontró una frecuencia genotípica del 82% para el homocigoto mutado C/C. La distribución de la frecuencia alélica se mostró de la siguiente manera: para MTHFR 677C>T se obtuvo 38% para el alelo mutado T y en cuanto a MTHFR 1298 A>C, 90% correspondió para el alelo mutado C. En el análisis estadístico no se encontró asociación genotípica ni alélica con las variables demográficas y clínicas