bluuebunny/crossref_metadata_2025_split huggingface dataset:
A crowdsourcing approach to track the expansion of the brown marmorated stinkbug Halyomorpha halys (Stål, 1855) in France
Authors: Chartois Marguerite , Streito Jean-Claude , Pierre Éric , Armand Jean-Marc , Gaudin Jonathan , Rossi Jean-Pierre 
Published: May 2021

Halyomorpha halys (Stål, 1855), the brown marmorated stinkbug (BMSB) is a highly successful invasive species, native to eastern Asia. It has managed to spread into North America and Europe in recent decades, causing severe damage to various crops. BMSB has been detected in Europe in 2004 and has since expanded in more than 20 countries from Sweden to Greece and Spain to Turkey, the South European Territory of Russia (Krasnodar region) and Abkhazia. In 2012, we set up a citizen science survey to monitor BMSB expansion in France.
The present crowdsourcing survey was initiated in 2012 and provided a large number of occurrence points of BMSB. These data allowed to track the expansion of the species in France from 2012 to 2019 and brought information about its phenology and distribution in various habitats. The dataset comprises both valid and invalid sightings, thereby allowing us to examine changes in the quality of citizen reports during the course of the survey. Despite a large proportion of misidentifications, the survey provided a large number of valid occurrences. Furthermore, valuable information on hemipterans of Pentatomidae and Coreidae families entering habitations were also gathered. The dataset also illustrates that, although designed for a large public, the Agiir application was mostly used by urban dwellers with very few sightings stemming from professionals of agricultural sectors.
Th17 Cells Contribute to the Pathology of Autoimmune Hypophysitis
Authors: Chalan Paulina , Thomas Nithya , Caturegli Patrizio 
Published: May 2021

Abstract
Autoimmune hypophysitis is classified as primary if its origin is idiopathic and secondary if it develops as a consequence of treatment with immune checkpoint inhibitors. Expanding use of immunotherapy has been paralleled by the increasing hypophysitis prevalence. However, understanding of the immune responses driving the disease remains limited. Using a mouse model of primary hypophysitis, we have identified CD4+ T lymphocytes to be the main pituitary-infiltrating immune cell population. Functional analysis showed that they display a Th17 and Th1/Th17 phenotype. To examine involvement of proinflammatory Th1, Th17, and Th1/17 subsets in hypophysitis, we have isolated RNA from the formalin-fixed paraffin-embedded pituitary specimens from 16 hypophysitis patients (three of whom had hypophysitis secondary to immune checkpoint inhibitors), 10 patients with adenoma, and 23 normal pituitaries obtained at autopsy. Transcript levels of IFN-γ, IL-17A, IL-4, IL-10, TGF-β, CD4, CD8α, and class II MHC transactivator were analyzed by the reverse transcription–quantitative PCR (RT-qPCR). Pituitary glands of patients with hypophysitis showed significantly higher IL-17A, CD4, and class II MHC transactivator mRNA levels compared with adenoma and normal pituitaries. All three secondary hypophysitis patients showed detectable IL-17A levels, but other cytokines were not detected in their pituitaries. Levels of IFN-γ, IL-4, IL-10, and TGF-β did not differ between the groups. TGF-β transcript was found in significantly fewer hypophysitis pituitaries (2 out of 16) compared with adenoma (7 out of 10) and normal pituitaries (11 out of 23). Presence of TGF-β in two hypophysitis patients was associated with significantly lower IL-17A mRNA levels compared with hypophysitis patients with no detectable TGF-β (p = 0.03).
The Roles of Type 2 Cytotoxic T Cells in Inflammation, Tissue Remodeling, and Prostaglandin (PG) D2 Production Are Attenuated by PGD2 Receptor 2 Antagonism
Authors: Chen Wentao , Luo Jian , Ye Yuan , Hoyle Ryan , Liu Wei , Borst Rowie , Kazani Shamsah , Shikatani Eric A. , Erpenbeck Veit J. , Pavord Ian D. , Klenerman Paul , Sandham David A. , Xue Luzheng 
Published: May 2021

Abstract
Human type 2 cytotoxic T (Tc2) cells are enriched in severe eosinophilic asthma and can contribute to airway eosinophilia. PGD2 and its receptor PGD2 receptor 2 (DP2) play important roles in Tc2 cell activation, including migration, cytokine production, and survival. In this study, we revealed novel, to our knowledge, functions of the PGD2/DP2 axis in Tc2 cells to induce tissue-remodeling effects and IgE-independent PGD2 autocrine production. PGD2 upregulated the expression of tissue-remodeling genes in Tc2 cells that enhanced the fibroblast proliferation and protein production required for tissue repair and myofibroblast differentiation. PGD2 stimulated Tc2 cells to produce PGD2 using the routine PGD2 synthesis pathway, which also contributed to TCR-dependent PGD2 production in Tc2 cells. Using fevipiprant, a specific DP2 antagonist, we demonstrated that competitive inhibition of DP2 not only completely blocked the cell migration, adhesion, proinflammatory cytokine production, and survival of Tc2 cells triggered by PGD2 but also attenuated the tissue-remodeling effects and autocrine/paracrine PGD2 production in Tc2 induced by PGD2 and other stimulators. These findings further confirmed the anti-inflammatory effect of fevipiprant and provided a better understanding of the role of Tc2 cells in the pathogenesis of asthma.
African Universities: Problems, COVID-19 & Efforts
Authors: Rios-Campos Carlos , Trujillo Jury Yesenia Aquino , Torres Antero Alexander Cabrera , Zapater Janeth Leticia Mora , Macias Patricia Mercedes Tapia , Malca María Raquel Maxe , Ramírez Italo Maldonado 
Published: May 2021

It is necessary to know the state of the Universities in Latin America. The general objective was determine the situation of African Universities: Problems, COVID-19 & Efforts. Methodology, in this research, 39 documents have been selected, carried out in the period 2016 - 2021; including: scientific articles, review articles and information from websites of recognized organizations. The keywords used in the searches were: African universities, African higher education, African universities COVID-19. Results, Universities in Africa receive inadequate funding, while maintenance costs rise; the Covid-19 pandemic had already had an impact on normal university expenditure and in short, the vision is to create world-class universities, based on African models and solutions. Conclusions, during the pandemic, African universities have closed their doors and due to the lack of technological resources and Internet access for students, classes cannot be taught properly.
Evaluación ergonòmica del puesto de trabajo de un alimentador de grano en un proceso de molienda de sorgo
Authors: Rosa Omar García de la , Estrada María de Lourdes Olivares , Soto Angelica Ortega , Rojas Guadalupe Ortega , Leonardo Ceciliano Hernández , La Rosa Rosenda García de , Vázquez Adiel García , La Rosa Héctor García de 
Published: May 2021

En la investigación se presenta un estudio ergonómico relacionado con la necesidad de modificar las tareas que tradicionalmente se efectúan en la molienda de sorgo, tomando como base la conservación de la salud del jornalero en su puesto de trabajo, para proponer una adaptación de las condiciones laborales de operación, con la innovación de buenas prácticas en el proceso productivo. Inicialmente se realizó la descripción del proceso de producción de harina de sorgo, mismo que se utiliza en la formulación de alimento balanceado para ganado bovino y posteriormente se realizó la evaluación ergonómica el puesto de trabajo del alimentador de grano de sorgo mediante la guía técnica española, método OWAS y método RULA. La metodología empleada correspondió a una investigación de tipo exploratoria y descriptiva para detectar posibles riesgos a los que el trabajador estaba expuesto por la manipulación de cargas.
El nivel de riesgo obtenido de la evaluación, pronosticaba posible daño al sistema musculo-esquelético y se requería aplicar acciones correctivas inmediatamente, puesto que la carga aplicada en estas posturas tiene efectos dañinos sobre el trabajador.
Los resultados obtenidos fueron diversos: Con relación a la Guía Técnica Española fue el hallazgo de una ecuación matemática que permite predecir el nivel de riesgo de acuerdo a la magnitud de la carga. También se aplicó el software Autocad para registrar los ángulos generados en cada postura que se usan para el método RULA y se observó que los ángulos del software y los obtenidos de la medición directa tuvieron un ligero desfasamiento. Para reducir el riesgo del alimentador de sorgo al molino de martillos, se adaptó un dispositivo de transporte de grano del vehículo (camioneta) al molino de martillos que disminuye notablemente las posturas críticas del trabajador, así como el diseño y construcción de un dispositivo de tracto-carga.
Efectos de estilos de liderazgo del director en la gestión de Instituciones Educativas
Authors: Collao Félix Eleazar De la Rosa , Vargas Isabel Menacho , Huari María Ysabel Alvarez , Mucha José Luis Camarena 
Published: May 2021

El problema de la gestión escolar es percibida como la deficiencia de la capacidad de los gestores educativos, en la cual el tipo de liderazgo no es claramente asumida por lo que los resultados en la escolaridad no alcancen las metas deseadas para el cambio sostenible del país, por ello, la importancia del estudio está en el fundamento que precisa la necesidad de generar conocimiento respecto a la forma de gestión, liderazgo así como del impacto en este nuevo proceso implementado a partir del año 2016, es un estudio de enfoque cuantitativo, básico de diseño no experimental con una muestra 116 docentes se utilizó la técnica de la encuesta y se aplicó instrumentos estandarizados con alta validez por juicio de expertos, los datos procesados en estadística descriptiva reportaron que el liderazgo es fuerte y la gestión educativa es buena, la prueba de hipótesis refrendo un Chi cuadrado de Wald 28,390 y una significancia de 0,000 menor a 0,05 determinando que el nivel de liderazgo y sus componentes inciden en los niveles de gestión de las instituciones educativas de la UGEL Parinacochas en la región Ayacucho, corroborando conclusiones de estudios previos.
Software Libre para el Análisis Espectral de Señales
Authors: Vanegas Carlos Alberto , De Caldas José , Guerrero Rocío Rodríguez , De Caldas Francisco José , Montiel Gerardo Castang 
Published: May 2021

En el presente artículo se realiza el análisis espectral de señales en particular de algunos de los códigos de línea más utilizados o comunes en la representación eléctrica de una secuencia binaria de datos , con el propósito de validar su comportamiento espectral, así como su dependencia de los parámetros tasa de bit (R) que corresponde a la velocidad a la cual se transmiten los datos, en bits por segundo; frecuencia (f) definida como aquellas bandas o rangos en las que se distribuyen los componentes de potencia, dada en hertz y tiempo de bit (Tb) que corresponde al tiempo que dura la presencia o transmisión de un bit, dada en segundos y su incidencia en las gráficas de la densidad espectral de potencia.
Se utiliza el software libre Python aplicado en casos de análisis de señales y en la enseñanza de temas de ingeniería, particularmente en la telemática y las comunicaciones.
Promoción de una alimentación saludable en la infancia y la adolescencia para el cumplimiento de los derechos del niñ
Authors: Ingelmo Raquel María Guevara , Litago José David Urchaga , Alonso Fernando González 
Published: May 2021

En la convención sobre los derechos del niño se contempla de la necesidad de garantizar el más alto nivel de salud posible en la infancia, siendo además este un objetivo prioritario a nivel educativo y sanitario en el mundo.
La alimentación, es uno de los factores determinantes que más influyen en el estado de salud de las personas, siendo la infancia y la adolescencia periodos clave. La Organización Mundial de la Salud señala que una alimentación inadecuada en la primera infancia es uno de los principales factores de riesgo de mala salud a lo largo de la vida, encontrándose además directamente relacionada con la aparición de enfermedades crónicas en la adultez.
La propia convención citada, señala además como derecho de este grupo de población el acceso a una educación integral que tome en consideración todas las dimensiones de la persona (física, mental y social).
Se presenta a continuación un estudio de los hábitos de alimentación de la población adolescente que, fundamentado en estos derechos del niño, justifica la importancia de programas de intervención a nivel educativo que favorezcan hábitos correctos de alimentación desde la infancia como medio de protección y promoción de la salud.
Ancient Egyptian Healers
Authors: Eltaieb Fatma 
Published: May 2021

Medicine in ancient Egypt was trying to restrain all malefic beings from the action and to preserve the well-being of the individual. Thus the initial statement that magic and science were one and only, a sole concept. Papyrus Edwin Smith mentioned diseases and surgery cases, 62 in total, fourteen with known treatments, and 48 without mentioning any treatment, maybe chronical diseases difficult to treat or even unknown diseases. At the same time as Papyrus Edwin Smith was bought in 1872 by Egyptologist George Ebers who gave it his name. It contains 877 medical treatises covering physical, mental and spiritual diseases. Papyrus Hearst Housed at the Bancroft Library, the University of California has eighteen pages, concentrating on the urinary tract treatments, blood, hair and snake and scorpion bites. Written in hieratic, its prescriptions go from a tooth that has fallen out to medicine to treat the lung and even human bites. Pigs and hippopotamus bites also. The nurse in Ancient Egypt could be female or male and was a highly respected medical professional although, as with midwives, there is no evidence of a school or professional training.
Measuring Nursing Sensitive Outcomes in Patient with Acute Myocardial Infarction: Tool Development and Validation
Authors: Yassien Sahar , Hamdi Mona 
Published: May 2021

Context: The outcomes movement is a young science, improving care by determining the outcomes of nursing interventions will give scientific validity to strategies that are used by nursing in a variety of venues. Cardiovascular nurses contribute significantly to health outcomes and frequently assume responsibility for the clinical and organizational processes to ensure positive outcomes for patients and families
Aims: The aims of this study were to identify nursing-sensitive outcomes in patients with acute myocardial infarction, to develop a tool to measure nursing-sensitive outcomes of caring patients with myocardial infarction, and to evaluate the content, face validity, reliability and nursing sensitivity of 46 nursing sensitive-outcomes concerning bio-psycho-socio- educational aspects of care for patients with myocardial infarction from the Nursing Outcomes Classification (NOC). Methods: A survey research design was used in this study to assess the content and face validity of the designed instrument and inter-rater reliability was utilized to assure its reliability. Thirty patients with acute myocardial infarction subjected to measuring their nursing-sensitive outcomes during their stay in the CCUs or intermediate units. Fifty-nine experts were invited to participate in this study. Nursing-Sensitive Outcomes Measuring Scale was developed and subjected to testing reliability, validity, and sensitivity
Results: Most of the studied outcomes showed a high degree of consistency as indicated by ICC that was above 0.900. 100% of the experts rated 14 out of 46 outcomes as very important; the remaining outcomes were assessed by more than 75% of the experts as important. Also, 18 out of 46 outcomes were rated by the 100% experts as very sensitive to the contribution of nursing intervention; no one outcome was rated as not important or not sensitive for nursing contribution. Conclusions: The study provided evidence of outcomes content validity, reliability, and nursing sensitivity of the studied outcomes. The study recommended the testing of NOC outcomes in various clinical settings with appropriate training for nurses, and the inclusion of NOC into nursing curricula to utilized in clinical education as a continuum for nursing diagno- ses classification.
PENILAIAN RISIKO BENCANA KAWASAN PARIWISATA PANTAI SAYUNG, KABUPATEN DEMAK
Authors: Rif’an Achmad Andi , Tyawati Agatia Wenan 
Published: May 2021

Sayung Tourist Area is located in the coastal area of Sayung District. This area consists of 3 tourist attractions: Morosari Beach, Mangrove Forest, and Tomb of Sheikh Mudzakir. Since several years this tourist area has experienced two natural disasters, namely tidal flood and coastal abrasion. This research aims to identify disaster hazards; identify vulnerabilities; identify the capacity of the community to deal with disasters; carry out risk assessments of rob and coastal abrasion in the Sayung tourist area; and suggests the direction for tourism development based on disaster risks in the area. Disaster risks assessment is conducted through several stages: first is to carry out disaster threat analysis, second vulnerability analysis, third capacity analysis, then to assess the risks of the Sayung Beach area which in this study is called multi-risks because it consists of more than one disasters. The last step is to analyze the direction of the development of tourist attractions based on the disaster analysis that has been carried out. Based on the disaster risk assessment that has been conducted, which includes hazard assessment, vulnerability assessment, and community capacity assessment, there are several areas that have a high risk of disasters, but some are low risk. All of the tourist attractions on the Sayung coast are all at high risk of disaster. The direction for the development of the area is to carry out the adaptation and mitigation strategies against tidal flood and abrasion.
Keywords: Tourism Area; Beach; Disaster Risk, Sayung Beach
PREFERENSI PENGUNJUNG TERHADAP PELAYANAN DI GRHATAMA PUSTAKA YOGYAKARTA
Authors: Priyanto Sabda Elisa , Sugiarto Eko 
Published: May 2021

The purpose of this paper is to describe the preferences of visitors to the service quality at Grhtama Pustaka Yogyakarta. The library has a function as a place of recreation that should be able to provide good services to visitors. The services provided must be based on visitor preferences when visiting and getting services. Visitor preferences for service quality that is tangible, reliability, responsiveness, assurance, and empathy. Grhtama Pustaka as the largest library in Yogyakarta must be able to provide good services, as a form of support to become a place of recreation in Yogyakarta. The method in this research is a descriptive study, with a population of visitors to Grhatama Pustaka, selected by the probability sampling method with a simple random sample technique, by interviewing 118 visitors. The results of this study found that tourist preferences for services in Grhatama Pustaka in the tangible part are strong preferences for visitors to visit, while the reliability, responsiveness, assurance, and empathy factors in library services are good preferences for visitors who need library services. Furthermore, hospitality services are needed if the manager wants to make visitors make Grhatama Pustaka a choice of the recreation area.
Key Word: Preference, Visitor, Service Quality, Library
THE RESPONSE OF THE COMMUNITY TOWARDS THE DEVELOPMENT OF TOURISM IN TEBING BREKSI YOGYAKARTA
Authors: Kurniawati Indri , Baiquni M , Wiyono Djoko 
Published: May 2021

The main focus of this research is to explain the community response of society in Sambirejo Village in developing tourism in Breksi Cliffs. Responses are assessed from three aspects namely: perception, attitude and participation. Data analysis is done by understanding and compiling data that has been collected systematically. The aim is to find the community’s response to tourism and the level of community participation in tourism management. The result of this study is two types of responses namely positive and negative. Positive response arises from people who want to take advantage of business opportunities, the formation of local institutions, and the change in status experienced by the management members of Breksi Cliffs. While the negative response arises from the group of miners who were directly affected by mine stop regulation. The miners reject the developing of tourism that they did not get a stable income if they work in the tourism industry.
Keywords: Breksi Cliff, Community Response, Tourism Development, Geotourism
EVALUASI ASPEK LINGKUNGAN TEBING BREKSI MENGGUNAKAN INDIKATOR SUSTAINABLE TOURISM UNWTO
Authors: Prasetyo Andreas Yogi 
Published: May 2021

Endowed with stunning natural beauty, Sleman has become a destination increasingly flooded by tourists from year to year. The rapid development of tourism does have a positive impact, especially on the economic side, but on the other hand, it can have a negative impact if the management does not prioritize the principles of sustainable tourism. The type of tourism that can be affected is tourism that relies on nature as its main attraction, Cliff of Breksi is one of them. Cliff of Breksi has experienced rapid development in terms of the number of tourist visits, but it has never been examined whether its management is following the principle of sustainability. The objectives of this research are: a) to identify the management of the environmental aspects of Cliff of Breksi, whether it is following the indicators of sustainable tourism from The World Tourism Organization (UNWTO) and b) determine what things need to be improved so that management can be more optimal. The research method used is a descriptive qualitative method. Research data were collected through in-depth interviews and observations. The results of the study indicate that the manager has so far had awareness and understanding in applying the principles of sustainable tourism as in the indicators of UNWTO sustainable tourism.
Keywords: evaluation of nature tourism, indicator, sustainable tourism
REVENGE TOURISM: ANALISIS MINAT WISATAWAN PASCA PANDEMI COVID-19
Authors: Sudjana Annisa Aulya , Aini Siti Nur , Nizar Hilman Khaerul 
Published: May 2021

This study aims to determine the interest of tourists after the Covid-19 pandemic related to the trend of "Revenge Tourism" or what is interpreted as revenge to travel after the Covid-19 pandemic. Apart from being able to know the interest of tourists from this research, it can also be known the type of tourism, budget, length of stay and other aspects of tourists that can be used as knowledge for tourism actors to make mitigation in tourist destinations to anticipate tourist surges and to help restoring Indonesian tourism after the pandemic. The research method used is descriptive quantitative research, collecting data using a questionnaire consisting of 3 parts of questions, about tourist demographics, questions using the AIDA scale (Attention, Interest. Desire, and Action), the last part of the questionnaire includes budget, length of stay, and top 3 destinations. The test subjects are people who are scattered in various provinces in Indonesia, and are limited to collecting a sample of at least 100 respondents. The results obtained were that the 3 most wanted destinations to be visited after the pandemic were DI Yogyakarta, Labuan Bajo and Bali. And the types of marine tourism, mountain nature tourism and culinary tourism are the types of tourism that are most in demand by tourists. The budget prepared by tourists for post-pandemic travel is in the range of 1-3 million rupiah and the time for traveling is 3-4 days.
Keywords: Revenge Tourism, Travel intention, AIDA Scale