bluuebunny/crossref_metadata_2025_split huggingface dataset:
Material characteristics of push-out tests
Authors: Vanova P , Orolin P , Dubecky D 
Published: December 2021

Abstract
Two types of push-out tests were carried out at the Centre of Research and Innovation in Construction, the Technical University of Košice - one at a composite based on steel continuous shear connector and the second one at the same connector, however made of glass-laminate material. For further research, the material characteristics of the material used needed to be found. In this article, the material tests performed as well as their results are presented.
Experimental analysis of shear connection effect composite beams with concrete
Authors: Weissova M , Dubecky D , Kvocak V 
Published: December 2021

Abstract
The subject of this research is the analysis of shear connection effect on the fiber glass reinforced composite beams. The research contains the detailed analysis of materials like concrete and fiber glass reinforced composite. The shear connection has been tested by the experiment of push out test run in the Centre of research and innovation in construction of Technical University of Košice. The shear connection has been tested on two types of connectors used on composite beams. The main idea of this research is find out whether it is possible to use the alternative material, which should substitute the steel. The aim of research is to design a type of connector for fiber reinforced composite materials or another composite materials developping in the world of material engineering. The part od research is devoted to the FEM analysis.
The trend of using solar energy of a green intelligent building and thermal energy storage to reduce the energy intensity of the building
Authors: Gorás M , Vranayová Z , Vranay F 
Published: December 2021

Abstract
The trend is to reduce the energy intensity of buildings. Thermal energy storage (TES) is the biggest challenge for buildings. It is a technology that supplies thermal energy by heating or cooling a tank, which then serves for the system in the building. Comparison of hitherto known systems ATES, BTES, PTES and research TTES. The most important factors for the accumulation of thermal energy are capacity (the energy stored in the system - depends on the storage process, the medium, and the size of the system), power (how fast the energy stored in the system can be discharged and charged), efficiency (the ratio of the energy provided to the user to the energy needed to charge the storage system. It accounts for the energy loss during the storage period and the charging/discharging cycle), storage (how long the energy is stored and lasts hours to months), charging and discharging (how much time is needed to charge or discharge the system), and cost (refers to capacity (€/kWh) or power (€/kW) of the TES system and depends on the capital and operation costs of the storage equipment and its lifetime).
A method of shaping an energy-efficient building envelope based on natural patterns in order to achieve save of energy
Authors: Wawrek I , Staňa R 
Published: December 2021

Abstract
This article aims to present an innovative way of designing objects called A method of shaping an energy-efficient building envelope based on natural patterns. The method uses currently available technologies in an unusual way. Digital photogrammetry data are inserted into a process of designing envelope structure of future objects. In the process of construction, this method counts on the use of all the advantages of 3D printing technology. This combination of the use of relatively innovative technologies in the process of design and construction of buildings opens up new possibilities for the design of the building envelope. Consequently, new building envelope shaping options create space for more efficient use of the energy savings associated with the building envelope shape as a building shape factor. The final design solution of the proposed building takes inspiration directly from the environment in which it is to be situated. Final design takes inspiration of its shape from the environment in which it will be built as a future object. As a result, the building works harmoniously and in accordance with the environment in which it was designed. This creates a pleasant ecological environment for its inhabitants and the surrounding area.
Introduction of cold-in-place recycling technology in practice as an innovative tool
Authors: Kovács R , Mandula J 
Published: December 2021

Abstract
Roads exposed to continuous and heavy traffic often shown sight of damage which particularly extend to the underlying layers of roads. Due to the advantages of less raw materials and fossil fuel consumption, lower carbon footprint and the capability of pavement performance improvement enormous effect have been done in the western countries over the past decades. Thanks to the efforts of some construction companies in Slovakia our focus in this paper on the innovation technology of cold-in-place recycling is given. The presumption of success of this innovative technology is the introduction and use of the set of a powerful and interconnected machines. This technology allows the repair of deep defects, rutting and fatigue failure, which cannot be done by surface treatment with significant reducing the impact on the environment, material, and economical savings. Moreover, it enables the repair of deep defects, rutting and fatigue failure, which cannot be done by surface treatment. To promote the widespread application of cold-in-place recycling technology in practice and to monitor the progress of developments, this article has examined and discussed the basic aspects of the use of this technology based on laboratory analyzes of recycled material.
Core–shell bioprinting as a strategy to apply differentiation factors in a spatially defined manner inside osteochondral tissue substitutes
Authors: Kilian David , Cometta Silvia , Bernhardt Anne , Taymour Rania , Golde Jonas , Ahlfeld Tilman , Emmermacher Julia , Gelinsky Michael , Lode Anja 
Published: December 2021

Abstract
One of the key challenges in osteochondral tissue engineering is to define specified zones with varying material properties, cell types and biochemical factors supporting locally adjusted differentiation into the osteogenic and chondrogenic lineage, respectively. Herein, extrusion-based core–shell bioprinting is introduced as a potent tool allowing a spatially defined delivery of cell types and differentiation factors TGF-β3 and BMP-2 in separated compartments of hydrogel strands, and, therefore, a local supply of matching factors for chondrocytes and osteoblasts. Ink development was based on blends of alginate and methylcellulose, in combination with varying concentrations of the nanoclay Laponite whose high affinity binding capacity for various molecules was exploited. Release kinetics of model molecules was successfully tuned by Laponite addition. Core–shell bioprinting was proven to generate well-oriented compartments within one strand as monitored by optical coherence tomography in a non-invasive manner. Chondrocytes and osteoblasts were applied each in the shell while the respective differentiation factors (TGF-β3, BMP-2) were provided by a Laponite-supported core serving as central factor depot within the strand, allowing directed differentiation of cells in close contact to the core. Experiments with bi-zonal constructs, comprising an osteogenic and a chondrogenic zone, revealed that the local delivery of the factors from the core reduces effects of these factors on the cells in the other scaffold zone. These observations prove the general suitability of the suggested system for co-differentiation of different cell types within a zonal construct.
Statistical physics of network structure and information dynamics
Authors: Ghavasieh A , De Domenico M 
Published: December 2021

Abstract
In the last two decades, network science has proven to be an invaluable tool for the analysis of empirical systems across a wide spectrum of disciplines, with applications to data structures admitting a representation in terms of complex networks. On the one hand, especially in the last decade, an increasing number of applications based on geometric deep learning have been developed to exploit, at the same time, the rich information content of a complex network and the learning power of deep architectures, highlighting the potential of techniques at the edge between applied math and computer science. On the other hand, studies at the edge of network science and quantum physics are gaining increasing attention, e.g., because of the potential applications to quantum networks for communications, such as the quantum Internet. In this work, we briefly review a novel framework grounded on statistical physics and techniques inspired by quantum statistical mechanics which have been successfully used for the analysis of a variety of complex systems. The advantage of this framework is that it allows one to define a set of information-theoretic tools which find widely used counterparts in machine learning and quantum information science, while providing a grounded physical interpretation in terms of a statistical field theory of information dynamics. We discuss the most salient theoretical features of this framework and selected applications to protein–protein interaction networks, neuronal systems, social and transportation networks, as well as potential novel applications for quantum network science and machine learning.
Heterogeneous genetic structure in eastern North American peat mosses (Sphagnum)
Authors: Duffy Aaron M , Ricca Mariana , Robinson Sean , Aguero Blanka , Johnson Matthew G , Stenøien Hans K , Flatberg Kjell Ivar , Hassel Kristian , Shaw A Jonathan 
Published: December 2021

Abstract
Bryophytes generally have broad geographical ranges that suggest high dispersal ability. The aim of this study was to test hypotheses about dispersal limitation, as indicated by isolation by distance, in four spore-producing species of the moss genus Sphagnum (Sphagnum carolinianum, Sphagnum missouricum, Sphagnum macrophyllum and Sphagnum pylaesii) and to assess whether plants in the southern USA harbour high levels of unique alleles and/or other indicators of exceptional genetic diversity. Isolation by distance was detected in all four species, but regional patterns of genetic structure were very species specific. Northern and southern genotype groups were detected in S. carolinianum and S. missouricum, but in S. pylaesii plants from the Adirondack Mountains of New York were genetically distinct from others to the north and south. One species, S. macrophyllum, exhibited differentiation between northern and southern genetic groups that appeared to reflect more ancient phylogenetic diversification.
Beyond the call of duty: A Qualitative study into the experiences of family members acting as a Nearest Relative in Mental Health Act assessments
Authors: Dixon Jeremy , Stone Kevin , Laing Judy 
Published: December 2021

Abstract
Research shows that tensions between family carers and professionals become acute where the issue of compulsory admission to hospital is at stake. In England and Wales, a specific family member is appointed to safeguard the interests of a person assessed under the Mental Health Act 1983. This currently occurs through the Nearest Relative (NR) role. The Government is proposing to replace this with a Nominated Person role, chosen by the service user. Drawing on the concept of carer burden, this study reports on the views of nineteen NRs in England to discover their experiences of being involved in a Mental Health Act assessment. Participants identified that they undertook the role due to a sense of duty. Their experiences were mixed with participants highlighting both feelings of distress during the assessment and feelings of relief once their relative had been detained. Participants reported feeling conflicted when their relative was detained and feelings of frustration towards mental health services. The findings have implications for proposals to reform the Mental Health Act 1983. They show that education and support programmes should be created for NRs/Nominated Persons and that research is needed to assess whether such support is effective at reducing carer burden.
Multi-criteria prioritization of the renewable power plants in Australia using the fuzzy logic in decision-making method (FMCDM)
Authors: Aryanfar Amin , Gholami Aslan , Ghorbannezhad Payam , Yeganeh Bijan , Pourgholi Mahdi , Zandi Majid , Stevanovic Svetlana 
Published: December 2021

Abstract
The presented study focused on developing an innovative decision-making framework to select the best renewable-power-plant technologies, considering comprehensive techno-economic and environmental variables. Due to the favourable conditions, Australia was selected as the case study. A fuzzy-logic method and analytical hierarchy process were applied to prioritize different renewable-energy power plants. The techno-economic factors included levelized cost of energy, initial cost, simple payback time, and operation and maintenance costs along with environmental factors including carbon payback time, energy payback time and greenhouse-gas emissions were used to rank the power plants. The results showed that the capital cost and simple payback time had the highest priority from an economic point of view. In comparison, greenhouse-gas emissions and carbon payback time were the dominant environmental factors. The analysis results provided economic and environmental priority tables for developing different power plants in the current state and a future scenario by 2030. The fuzzy results and pairwise composite matrix of alternatives indicated that the onshore wind, offshore wind, single-axis tracker polycrystalline photovoltaic, single-axis tracker monocrystalline photovoltaic, fix-tilted polycrystalline photovoltaic and fix-tilted monocrystalline photovoltaic scored the highest in the current state. In contrast, by 2030, the single-axis tracker photovoltaic power plants will be the best choice in the future scenario in Australia. Finally, the results were used and analysed to recommend and suggest several policy implementations and future research studies.
A maximum power point tracking strategy applied to building integrated photovoltaics
Authors: Cui Jian , Fang Jianjun 
Published: December 2021

Abstract
To solve the problem of permanent-shadow shading of photovoltaic buildings, a maximum power point tracking (MPPT) strategy to determine the search range by pre-delimiting area is proposed to improve MPPT efficiency. The single correspondence between the solar-cell current–voltage (I–V) curve and the illumination conditions was proved by using the single-diode model of photovoltaic cells, thus proving that a change in the illumination conditions corresponds to a unique maximum power point (MPP) search area. According to the approximate relationship between MPP voltage, current and open-circuit voltage and short-circuit current of a photovoltaic module, the voltage region where the MPP is located is determined and the global maximum power point is determined using the power operating triangle strategy in this region. Simulation carried out in MATLAB proves the correctness and feasibility of the theoretical research. Simulation results show that the MPPT strategy proposed in this paper can improve the average efficiency by 1.125% when applied in series as building integrated photovoltaics.
Instantaneous neural processing of communicative functions conveyed by speech prosody
Authors: Tomasello Rosario , Grisoni Luigi , Boux Isabella , Sammler Daniela , Pulvermüller Friedemann 
Published: December 2021

Abstract
During conversations, speech prosody provides important clues about the speaker’s communicative intentions. In many languages, a rising vocal pitch at the end of a sentence typically expresses a question function, whereas a falling pitch suggests a statement. Here, the neurophysiological basis of intonation and speech act understanding were investigated with high-density electroencephalography (EEG) to determine whether prosodic features are reflected at the neurophysiological level. Already approximately 100 ms after the sentence-final word differing in prosody, questions, and statements expressed with the same sentences led to different neurophysiological activity recorded in the event-related potential. Interestingly, low-pass filtered sentences and acoustically matched nonvocal musical signals failed to show any neurophysiological dissociations, thus suggesting that the physical intonation alone cannot explain this modulation. Our results show rapid neurophysiological indexes of prosodic communicative information processing that emerge only when pragmatic and lexico-semantic information are fully expressed. The early enhancement of question-related activity compared with statements was due to sources in the articulatory-motor region, which may reflect the richer action knowledge immanent to questions, namely the expectation of the partner action of answering the question. The present findings demonstrate a neurophysiological correlate of prosodic communicative information processing, which enables humans to rapidly detect and understand speaker intentions in linguistic interactions.
Development and Validation of a Stability-Indicating Reversed-Phase HPLC Method for Assay and Estimation of Related Substances of Ivermectin in an Oral Paste
Authors: Padivitage Nilusha , Tian Jingzhi , Wang Lin , Zhuang Jinyou , McAdoo Andrew , Zhao Daoli , Rustum Abu M 
Published: December 2021

Abstract
Ivermectin is a potent semi-synthetic antiparasitic drug used in veterinary medicine. A reversed-phase high performance liquid chromatography (HPLC) method has been developed and validated for the identification and assay of Ivermectin, including the identification and estimation of its related impurities in an oral paste. Analytes were separated using a gradient elution at a flow rate of 1.5 mL/min on a Zorbax Extend-C18 column (150 mm × 4.6 mm i.d., 3.5-μm particle size) maintained at 30 °C. The mobile phase was composed of water as mobile-phase A and acetonitrile/methanol (85/15, v/v) as mobile-phase B. Ultraviolet detection at 245 nm was employed to monitor the analytes. Limit of quantitation (LOQ) and limit of detection (LOD) of the method are 0.6 and 0.2 μg/mL, respectively. The validation results demonstrated excellent linearity of the method in the range of 0.1–150% of the analytical concentration (0.6 mg/mL) of the method. The stability-indicating capability of the method has been demonstrated by adequately separating the degradation products from the stress degraded samples of the oral paste as per method validation requirements prescribed in the current International Council for Harmonisation guidelines.
The unmet need of evidence-based therapy for patients with advanced chronic kidney disease and heart failure
Authors: Ortiz Alberto , Navarro-González Juan F , Núñez Julio , de la Espriella Rafael , Cobo Marta , Santamaría Rafael , de Sequera Patricia , Díez Javier 
Published: December 2021

ABSTRACT
Despite the high prevalence of chronic kidney disease (CKD) and its high cardiovascular risk, patients with CKD, especially those with advanced CKD (stages 4–5 and patients on kidney replacement therapy), are excluded from most cardiovascular clinical trials. It is particularly relevant in patients with advanced CKD and heart failure (HF) who have been underrepresented in many pivotal randomized trials that have modified the management of HF. For this reason, there is little or no direct evidence for HF therapies in patients with advanced CKD and treatment is extrapolated from patients without CKD or patients with earlier CKD stages. The major consequence of the lack of direct evidence is the under-prescription of HF drugs to this patient population. As patients with advanced CKD and HF represent probably the highest cardiovascular risk population, the exclusion of these patients from HF trials is a serious deontological fault that must be solved. There is an urgent need to generate evidence on how to treat HF in patients with advanced CKD. This article briefly reviews the management challenges posed by HF in patients with CKD and proposes a road map to address them.
Current recommendations and uncertainties for surgical treatment of infective endocarditis: a comparison of American and European cardiovascular guidelines
Authors: Wang Andrew , Fosbøl Emil L 
Published: December 2021

Abstract
Surgery is an effective therapy in the treatment of left-sided infective endocarditis (IE) in patients for whom antibiotic treatment alone is unlikely to be curative or may be associated with ongoing risk of complications. However, the interplay between indication for surgery, its risk, and timing is complex and there continue to be challenges in defining the effects of surgery on disease-related outcome. Guidelines published by the American College of Cardiology/American Heart Association and the European Society of Cardiology provide recommendations for the use of surgery in IE, but these are limited by a low level of evidence related to predominantly observational studies with inherent selection and survival biases. Evidence to guide the timing of surgery in IE is less robust, and predominantly based on expert consensus. Delays between IE diagnosis and recognition of an IE complication as a surgical indication and transfers to surgical centres also impact surgical timing. This comparison of the two guidelines exposes areas of uncertainty and gaps in current evidence for the use of surgery in IE across different indications, particularly related to its timing and consideration of operative risk.
Improving patient care pathways in otitis externa
Authors: Mather Michael W , Mohammed Hassan , Wilson Janet A 
Published: December 2021

Abstract

Introduction
Referrals for otitis externa (OE) have dramatically increased but the reasons for this remain unclear. We aim to characterize management of patients both pre- and post-referral to identify areas of improvement at the primary–secondary care interface.

Methods
Questionnaire study from consultant-led research clinic specifically set up to prospectively analyse OE referrals at a tertiary referral centre for Otolaryngology.

Results
Sixty-two patients were included; 63% female, median age 57 years. One was excluded (clinically not OE). Most patients had multiple primary care visits before referral (average 4 GP; 2 practice nurse). Sixty per cent had received oral antibiotics (16% multiple classes). Eighteen per cent had never had ear drops. Thirty-nine per cent were not advised to keep ears dry. Twenty-one per cent had dermatitis; 13% contact allergy, 30% systemic allergy, 5% diabetes. Less than 10% had narrow canals. Thirty-six per cent had active discharge but &lt;7% needed a wick. Approximately 75% appear suitable for community aural care clinics.

Conclusions
OE occurs most commonly in female patients, often with associated risk factors. Patients often consult primary care several times prior to referral. Lifestyle advice and ototopical drops are frequently overlooked; instead, often inappropriately treated with oral antibiotics. Most ears were anatomically normal, and community aural care clinics may have a role in more timely and accessible treatment.