bluuebunny/crossref_metadata_2025_split huggingface dataset:
CAPACITAÇÃO DE APROVEITAMENTO INTEGRAL DOS ALIMENTOS COM FEIRANTES DO PROGRAMA DE ECONOMIA SOLIDÁRIA (PAES) -UNESC
Authors: Gabriel Filipe Fernandes , Monteiro Isadora De Oliveira , Martins Aline , Fabris Fabiane Maciel 
Published: March 2021

A economia solidária organiza-se a partir de fatores humanos, favorecendo as relações sociais e da propriedade comunitária e da gestão democrática. Os produtos colônias assim são denominados na região, são alimentos tradicionalmente produzidos em casa e nos estabelecimentos rurais para o auto consumo familiar pelos agricultores descendentes de italianos e alemães, também chamados de “colonos”. O grupo de feirantes é composto por produtores da região carbonífera de Santa Catarina, e estão ligadas as cooperativas. Devido à grande procura de clientes por alimentos mais saudáveis, funcionais e regionais, surge o interesse dos feirantes em procurar se especializar. E através do projeto de extensão “Ações de Alimentação e Nutrição Solidária”. Participaram da aula prática e teórica 5 feirantes, realizadas em um encontro com duração de cinco horas, no laboratório de técnica dietética da Universidade do Extremo Sul Catarinense (UNESC), durante o mês de maio de 2019 no turno vespertino. Ministradas por 2 bolsistas 2 voluntariados e 1 professora do projeto de extensão. A aula teórica foi por meio de exposição de data show e uma apostila, com informações sobre o aproveitamento integral dos alimentos.Para o bolo de casca de banana, foram atribuídos 3 muito bom (75%) e 1 bom (25%); carne de casca de banana, teve 3 muito bom (75%) e 1 bom (25%); coxinha de aipim com carne de banana, obteve 4 muito bom (100%); cookies de banana e aveia com coco, apresentou 4 muito bom (100%); muffin de tomate, 3 muito bom (75%) e 1 bom (25%); pão colorido, 3 muito bom (75%) e 1 bom (25%), patê de ricota 1 muito bom (25|%), 2 bom (50%) e 1 nem ruim nem bom (25%); lasanha de abobrinha e patê de ricota, possuiu 4 muito bom (100%). Com isso, pode-se concluir que a capacitação proporcionou aos extensionistas a oportunidade de compartilhar seus conhecimentos da graduação e aprender ainda mais sobre o uso integral dos alimentos. Aos feirantes a capacitação possibilitou sugestões de novas receitas para serem comercializadas, e o mais importante, utilizando partes dos alimentos que geralmente seriam descartadas.
HUBUNGAN ANTARA LINGKUNGAN KELUARGA DAN KEMANDIRIAN BELAJAR DENGAN PRESTASI BELAJAR MATA PELAJARAN PRODUKTIF SISWA KELAS XI SMK NEGERI 34 JAKARTA
Authors: Septyani Awalia , Suyitno  , Daryanto  
Published: March 2021

ABSTRACT
The purpose of this study was to determine the relationship between family environment and learning independence with the learning achievement. In this study using the ex post facto descriptive correlative method with a quantitative approach. The population in this study were students of class XI TITL at SMK Negeri 34 Jakarta as many as 68 people. Data collection methods for family environment variables and learning independence using questionnaire models with Likert Scale, while for the variable learning achievement of productive subjects using the method of documentation in the form of pure value Mid-Term Exams. The results showed that the hypothesis test with a significance level of 5% obtained rcount = 0,711 and value of rtable = 0,239 where rcount > rtable shows that there is a relationship between variables, then the value of Fcount = 33,23 and Ftable = 3.14 where Fcount > Ftable shows that there is a significance between variables and a determination value of 0,505 which indicates that family environment and learning independence together have an effect of 51% on learning achievement.

ABSTRAK
Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara lingkungan keluarga dan kemandirian belajar dengan prestasi belajar mata pelajaran produktif. Pada penelitian ini menggunakan metode ex post facto yang bersifat deskriptif korelatif dengan pendekatan kuantitatif. Populasi dalam penelitian ini adalah siswa/i kelas XI TITL di SMK Negeri 34 Jakarta sebanyak 68 orang. Metode pengambilan data untuk variabel lingkungan keluarga dan kemandirian belajar menggunakan kuesioner model angket dengan Skala Likert, sedangkan untuk variabel prestasi belajar mata pelajaran produktif menggunakan metode dokumentasi berupa nilai murni Ujian Tengah Semester. Hasil perhitungan menunjukkan bahwa uji hipotesis dengan taraf signifikan 5% di peroleh nilai rhitung = 0,711 dan nilai rtabel = 0,239 dimana rhitung > rtabel menunjukkan bahwa terdapat hubungan antar variabel, kemudian nilai Fhitung = 33,23 dan Ftabel = 3,14 dimana Fhitung > Ftabel menunjukkan bahwa terdapat signifikansi antar variabel dan nilai determinasi sebesar 0,505 yang menunjukkan bahwa lingkungan keluarga dan kemandirian belajar secara bersama-sama memiliki pengaruh sebesar 51% terhadap prestasi belajar.
STRATEGY FOR SPORT SCIENCE PROGRESSIVE
Authors: Ardo Okilanda Ardo Okilanda , Dlis Firmansyah , Humaid Hidayat , Putra Dede Dwiansyah 
Published: March 2021

The objective of this research is sport science campaign to society. This research used survey qualitative method conducted to students with 90 respondents made campaign task and used Instagram actively. The survey result from student’s task of sport science campaign by using Instagram the students was divided into three categories, they were 15% students used Instagram no more than one hour, 30% used Instagram for two hours and more than 65% used Instagram more than three hours. Based on the result, students have a big effect to contribute society knowledge in sport science by using Instagram.
Keywords: Community, Instagram, Sport Science
Time Since Burning and Rainfall Characteristics Impact Post-Fire Debris-Flow Initiation and Magnitude
Authors: McGuire Luke A. , Rengers Francis K. , Oakley Nina , Kean Jason W. , Staley Dennis M. , Tang Hui , de Orla-Barile Marian , Youberg Ann M. 
Published: March 2021

ABSTRACTThe extreme heat from wildfire alters soil properties and incinerates vegetation, leading to changes in infiltration capacity, ground cover, soil erodibility, and rainfall interception. These changes promote elevated rates of runoff and sediment transport that increase the likelihood of runoff-generated debris flows. Debris flows are most common in the year immediately following wildfire, but temporal changes in the likelihood and magnitude of debris flows following wildfire are not well constrained. In this study, we combine measurements of soil-hydraulic properties with vegetation survey data and numerical modeling to understand how debris-flow threats are likely to change in steep, burned watersheds during the first 3 years of recovery. We focus on documenting recovery following the 2016 Fish Fire in the San Gabriel Mountains, California, and demonstrate how a numerical model can be used to predict temporal changes in debris-flow properties and initiation thresholds. Numerical modeling suggests that the 15-minute intensity-duration (ID) threshold for debris flows in post-fire year 1 can vary from 15 to 30 mm/hr, depending on how rainfall is temporally distributed within a storm. Simulations further demonstrate that expected debris-flow volumes would be reduced by more than a factor of three following 1 year of recovery and that the 15-minute rainfall ID threshold would increase from 15 to 30 mm/hr to greater than 60 mm/hr by post-fire year 3. These results provide constraints on debris-flow thresholds within the San Gabriel Mountains and highlight the importance of considering local rainfall characteristics when using numerical models to assess debris-flow and flood potential.
Measurements of Velocity Profiles in Natural Debris Flows: A View behind the Muddy Curtain
Authors: Nagl Georg , Hübl Johannes , Kaitna Roland 
Published: March 2021

ABSTRACT
The internal deformation behavior of natural debris flows is of interest for model development and model testing for debris-flow hazard mitigation. Up to now, only a few attempts have been made to measure velocity profiles in natural debris flows due to the low predictability and high destructive power of these flows. In this contribution, we present recent advances to measure in-situ velocity profiles together with flow parameters like flow height, basal normal stress, and pore fluid pressure. This was accomplished by constructing a fin-shaped monitoring barrier with an array of paired conductivity sensors in the middle of Gadria Creek, Italy. We present results from two natural debris-flow events. Compared to the first event on July 10, 2017, the second event on August 19, 2017, was visually more liquid. Both debris flows exhibited significant longitudinal changes of flow properties like flow height and density. The liquefaction ratios reached values up to unity in some sections of the flows. Velocity profiles for the July event were mostly concave-up, while the profiles for the more liquid event in August were linear to convex. These measurements provide new insights into the dynamics of real-scale debris flows.
Hybrid Physics-Based and Data-Driven Modeling for Improved Standpipe Pressure Prediction
Authors: Erge Oney , van Oort Eric 
Published: March 2021

Abstract
During drilling operations, it is common to see pump pressure spikes when flow is initiated, including after a connection or after a prolonged break in drilling operations. It is important to be able to predict the magnitude of such pressure spikes to avoid compromising wellbore integrity. This study shows how a hybrid approach using data-driven machine learning coupled with physics-based modeling can be used to accurately predict the magnitude of pressure spikes.
To model standpipe pressure behavior, machine learning techniques were combined with physics-based models via a rule-based, stochastic decision-making algorithm. To start, neural networks and deep learning models were trained using time-series drilling data. From there, physics-based equations that model the pressure required to break the mud's gel strength as well as the flow of non-Newtonian fluids through the entire circulation system were used to simulate standpipe pressure. Then, these two highly different methods for predicting/modeling standpipe pressure were combined by a hidden Markov model using a set of rules and transition probabilities.
By combining machine learning and physics-based approaches, the best features of each model are leveraged by the hidden Markov model, yielding a more accurate and robust prediction of pressure. A similar result is not achievable with a purely data-driven black-box model, because it lacks a connection to the underlying physics. Our study highlights how drilling data analysis can be optimally leveraged. The overarching conclusion: hybrid modeling can more accurately predict pump pressure spikes and capture the transient events at flow initiation when compared to physics-based or machine learning models used in isolation. Moreover, the approach is not limited to pressure behavior but can be applied to a wide range of well construction operations. The proposed approach is easy to implement and the details of implementation are presented in this study.
Being able to accurately model and manage the pressure response during drilling operations is essential, especially for wells drilled in narrow-margin environments. Pressure can be more accurately predicted through our proposed hybrid modeling, leading to safer, more optimized operations.
High-throughput detection of SARS-CoV-2
Authors: Aynaud Marie-Ming , Hernandez J. Javier , Barutcu Seda , Braunschweig Ulrich , Chan Kin , Pearson Joel D. , Trcka Daniel , Prosser Suzanna L. , Kim Jaeyoun , Barrios-Rodiles Miriam , Jen Mark , Song Siyuan , Shen Jess , Bruce Christine , Hazlett Bryn , Poutanen Susan , Attisano Liliana , Bremner Rod , Blencowe Benjamin J. , Mazzulli Tony , Han Hong , Pelletier Laurence , Wrana Jeffrey L. 
Published: March 2021

Abstract
Population scale sweeps of viral pathogens, such as SARS-CoV-2, require high intensity testing for effective management. This protocol describes the “Systematic Parallel Analysis of RNA coupled to Sequencing for Covid-19 screening” (C19-SPAR-Seq), a multiplexed, scalable, readily automated platform for SARS-CoV-2 detection that is capable of analyzing tens of thousands of patient samples in a single run. To address strict requirements for control of assay parameters and output demanded by clinical diagnostics, we employed a control-based Precision-Recall and Receiver Operator Characteristics (coPR) analysis to assign run-specific quality control metrics. C19-SPAR-Seq coupled to coPR on a trial cohort of several hundred patients performed with a specificity of 100% and sensitivity of 91% on samples with low viral loads, and a sensitivity of > 95% on high viral loads associated with disease onset and peak transmissibility. This study establishes the feasibility of employing C19-SPAR-Seq for the large-scale monitoring of SARS-CoV-2 and other pathogens.
Salmonella Typhimurium L Forms Induce Vascular Endothelial Cell Apoptosis via Mitochondrial-dependent Pathway
Authors: Zhai Jinhai , Yang Cuiping , Zhang Tao , Chen Dengyu 
Published: March 2021

Abstract
BackgroundSalmonella typhimurium is a pathogenic gram-negative bacterium, which is found primarily in the intestinal lumen. It often causes diarrhea in infants and young children and leads to food poisoning, as well as septicemia and septic shock. In this study, we investigated the phenomenon and mechanism of vascular endothelial cells apoptosis induced by Salmonella typhimurium L forms, in order to recognize and control Salmonella typhimurium L-form infection.Methods The apoptosis of vascular endothelial cells at 8 hours after infection with Salmonella typhimurium L forms was determined by flow cytometric assay and fluoroscopy of Annexin V-FITC/PI staining. Caspase-9 was detected by spectrophotometer. Results Salmonella typhimurium L forms can induce apoptosis of vascular endothelial cells, with significant difference in the apoptosis rate compared with the control. Caspase-9 expression is higher than that of the control. Conclusion The ability to induce cell apoptosis of vascular endothelial cells by Salmonella typhimurium L forms may be related to mitochondria apoptosis pathway depending on Caspase-9.
Realizing the potential of metallic iron for environmental remediation: Flee or adapt?
Authors: Hu Rui , Yang Huichen , Cao Viet , Amoah Bernard Konadu , Ndé-Tchoupé Arnaud Igor , Gwenzi Willis , Ruppert Hans , Noubactep Chicgoua 
Published: March 2021

Abstract
The evidence that metallic iron (Fe0) is not an environmental reducing agent has been declared to be a claim. Researchers presenting their findings in a scientific journal have to accept the burden of proving that their argumentation has any validity. This 30-year-lasting discussion within the Fe0 remediation community is alien to graduate chemists, as it is a century old electrochemistry knowledge. Nevertheless, the peer review literature on "remediation using Fe0" seems to be aggressively controlled by self-appointed experts (e.g., journal editors) who are not tolerating any alternative thinking. This communication demonstrates the fallacy of the view that Fe0 donates any electron to a dissolved species. The sole goal is to reconcile a proven efficient technology with his scientific roots, and enable the design of better Fe0 remediation systems.
MiR-218-5p&nbsp;promotes breast cancer progression via LRIG1
Authors: Qian Mingping , Xu Hui , Song Hongming , Xi Hao , Fang Lin 
Published: March 2021

Abstract
Background : MiR-218-5p is a small non-coding RNA acting as either oncogenes or tumor suppressor genes in human cancer. The expression levels of some miRNAs in human breast cancer plays a potential role in disease pathogenesis. Methods : Thirty pairs of invasive ductal carcinoma and adjacent specimens were included in the study. Breast tissues cell lines MCF-7 and MDA-MB-231 were identified as a breast cancer research cell line. MiR-218-5p mimics, miR-218-5p inhibitor, or negative controls were transfected. Specific antibodies were probed with LRIG1, ErbB2, and EGFR. Proliferation, migration, cell cycle and apoptosis, dual-luciferase reporter assay and immunohistochemistry were used to analyze miR-218-5p、LRIG1 and so on. Results : It was shown that miR-218-5p expression was higher in 30 breast cancer specimens than adjacent normal breast tissues. In human breast cancer cells MCF-7 and MDA-MB-231, restoring miR-218-5p promoted cell proliferation and migration and inhibited cell apoptosis and cell cycle arrest in the G1 stage. Luciferase assays indicated miR-218-5p could bind with its putative target site in the 3'-untranslated region (3'-UTR) of LRIG1. RT-qPCR, western blot, and immunocytochemistry analyses all indicated miR-218-5p overexpression results in LRIG1 downregulation at the mRNA and protein levels. ErbB2 and EGFR were found to be downstream effectors of miR-218-5p. Conclusion : MiR-218-5p promotes ErbB2 and EGFR expression by inhibiting LRIG1 in breast cancer cells, which suggests miR-218-5p and LRIG1 may act as an oncogene in breast cancer and it could be used as a therapeutic target for breast cancer treatments. Keywords: Breast cancer; miR-218-5p; LRIG1; Oncogene
Natural regeneration of Pinus spp. around seed production areas and orchards
Authors: Santos Magda , Araujo Marcio , Silva Paulo 
Published: March 2021

Abstract
This study aims at determining the establishment potential of the main species of the Pinus genus planted in Brazil and broaden the knowledge on the conditions that facilitate the invasion. The density of regenerants neighboring pine stands planted with 35 populations of Pinus spp. (P. caribaea (var. bahamensis and var. caribaea), P. elliottii, P. kesiya, P. merkussi, P. oocarpa, P. patula, P. pseudstrobus, P. strobus, P. taeda, and P. tecunomanii) was evaluated in three locations in the state of São Paulo. The vegetal covers neighboring the pine stands were evaluated regarding native vegetation occupation, open area, and eucalypts plantation. The census of regenerants was conducted up to 100 m away from the pine stand edges; samples were collected over an area divided into four 25m-wide transects. In each transect, the regenerants were quantified and classified into three size classes: sprouts (≤ 0.3 m), seedlings (≥ 0.3 m ≤ 1.0 m), and trees (> 1.0 m). The results indicate that Pinus elliottii is the species with the greatest invasion potential in the studied areas since it adapts to different environments. Areas without established vegetation favored regeneration, indicating the effect of the environment on regeneration occurrence. The number of regenerants increased near the seed source but decreased significantly between 50 and 100 m away, despite the directional effect of the prevailing winds and the long-distance dispersal capacity of the genus.
Environmental Impacts to Surface Water from Confined and Grass-Based Dairy Farms
Authors: Li Aoze , Zhu Jiahui 
Published: March 2021

Abstract
There is little research on the effects of confined dairy farms and grass-based dairy farms on the surrounding surface water environment. This study was conducted through sampling and analysis of seven dairy farms in the Northern Hemisphere, especially between 38-degree to 45-degree north latitude. The correlation between the effect of confined dairy farms and grass-based dairy farms on the surrounding surface water (mainly Phosphorus runoff and Nitrogen precipitation) and pasture scale and waste management were obtained.
Traditional Water Management Systems in Afghanistan; Lessons for the Future
Authors: Mahaqi Ali 
Published: March 2021

Abstract
As far as the Afghans could remember, water resources management was a fundamental part of their life. They learned through history to administer the available water supplies to deal with their environment’s challenges. Also, climate change intensifies the problems at present. The Afghan communities by using techniques and rules could manage the water. Mir Ab is the person, administering the water distribution systems and works along with local communities to regulate water efficiently and fairly. Mir Ab controls the systems such as karezes, canals, and wells which has important role in different places around Afghanistan based on their geographical settings. Firstly, Kareze plays a critical role in water management and consisted of multiple shafts and main inclined tunnel to bring subsurface water to the surface. Secondly, Canals brings waters to the areas where are rather close to main rivers. Thirdly, wells used in most area and the common one, traditionally, they provide drinking water for societies. Understanding the traditional water supplies facilities in the country remind Afghan people that water is highly valuable commodity, and then the current water associated officials should pay more attention and do their best to manage it. The main goal of this work is highlighting the importance of water for our ancestors, while it ignored significantly by current Government of Afghanistan. Besides, providing a guideline map to look forward and applying right strategies. In short, we hope this paper remind those who are responsible in this field to value the importance of water in Afghanistan.
Cornel iridoid glycoside ameliorated Alzheimer's disease-like pathologies and necroptosis through RIPK1/MLKL pathway in young and aged SAMP8 mice
Authors: Ma Denglei , Li Yanzheng , Zhu Yanqiu , Wei Weipeng , Zhang Li , Li Yali , li lin , Zhang Lan 
Published: March 2021

Abstract
Background

Aging is an important risk factor for sporadic Alzheimer’s disease (AD) and other neurodegenerative diseases. Senescence-accelerated mouse-prone 8 (SAMP8) is used as an animal model for brain aging and sporadic AD researches. The aim of the current study was to investigate the pharmacological effects of cornel iridoid glycoside (CIG), an active ingredient of Cornus officinalis, on AD-type pathological changes in young and aged SAMP8 mice.
Methods

Nissl and immunohistochemical staining was applied to detect NeuN-labeled neurons and myelin basic protein-labeled myelin sheath,. Western blotting was used to detect the expression levels of related proteins of synapse, APP processing and necroptosis.
Results

The results showed that SAMP8 mice at the age of 6 and 14 months exhibited age-related neuronal loss, demyelination, synaptic damage, and APP amyloidogenic processing. In addition, the increased levels of receptor-interacting protein kinase-1 (RIPK1), mixed lineage kinase domain-like protein (MLKL) and p-MLKL indicating necroptosis were found in the brain of SAMP8 mice. Intragastric administration of CIG for 2 months alleviated neuronal loss and demyelination, increased the expression of synaptophysin, postsynaptic density protein 95 and AMPA receptor subunit 1, elevated the levels of soluble APPα fragment and a disintegrin and metalloproteinase 10 (ADAM10), and decreased the levels of RIPK1, p-MLKL and MLKL in the brain of young and aged SAMP8 mice.
Conclusion

This study denoted that CIG might be a potential drug for aging-associated neurodegenerative diseases such as AD.