bluuebunny/crossref_metadata_2025_split huggingface dataset:
Topographic volume-standardization atlas of the human brain
Authors: Akeret Kevin , van Niftrik Christiaan Hendrik Bas , Sebök Martina , Muscas Giovanni , Visser Thomas , Staartjes Victor E. , Marinoni Federica , Serra Carlo , Regli Luca , Krayenbühl Niklaus , Piccirelli Marco , Fierstra Jorn 
Published: May 2021

AbstractSpecific anatomical patterns are seen in various diseases affecting the brain. Clinical studies on the topography of pathologies are often limited by the absence of a normalization of the prevalence of pathologies to the relative volume of the affected anatomical structures. A comprehensive reference on the relative volumes of clinically relevant anatomical structures serving for such a normalization, is currently lacking. The analyses are based on anatomical high-resolution three-dimensional T1-weighted magnetic resonance imaging data of 30 healthy Caucasian volunteers, including 14 females (mean age 37.79 years, SD 13.04) and 16 males (mean age 38.31 years, SD 16.91). Semi-automated anatomical segmentation was used, guided by a neuroanatomical parcellation algorithm differentiating 96 structures. Relative volumes were derived by normalizing parenchymal structures to the total individual encephalic volume and ventricular segments to the total individual ventricular volume. The present investigation provides the absolute and relative volumes of 96 anatomical parcellation units of the human encephalon. A larger absolute volume in males than in females is found for almost all parcellation units. While parenchymal structures display a trend towards decreasing volumes with increasing age, a significant inverse effect is seen with the ventricular system. The variances in volumes as well as the effects of gender and age are given for each structure before and after normalization. The provided atlas constitutes an anatomically detailed and comprehensive analysis of the absolute and relative volumes of the human encephalic structures using a clinically oriented parcellation algorithm. It is intended to serve as a reference for volume-standardization in clinical studies on the topographic prevalence of pathologies.
Growing up after childhood cancer: maturity and life satisfaction in young adulthood
Authors: Dattilo Taylor M. , Olshefski Randal S. , Nahata Leena , Hansen-Moore Jennifer A. , Gerhardt Cynthia A. , Lehmann Vicky 
Published: May 2021

Abstract
Purpose
Young individuals face a variety of developmental tasks as they mature into adulthood. For survivors of childhood cancer, growing up may be more difficult due to their illness and late effects from treatment. This study is the first to quantitatively examine perceptions of maturity and how these perceptions contribute to satisfaction with life among young adult survivors of childhood cancer.

Methods
Ninety survivors of childhood cancer (Mage = 29.8; 7–37 years post-diagnosis) were recruited to complete online surveys on how mature they felt relative to peers, their perceived maturity on three domains (financial, personal, social), and life satisfaction.

Results
Most survivors (62%; n = 56) felt they grew up faster than their peers, and over half (56%; n = 50) felt more mature. Perceived maturity was high on all three domains, but brain tumor survivors reported significantly lower maturity than other survivors (d = 0.76–1.11). All maturity domains were positively associated with life satisfaction (r = .49–.56). Hierarchical linear regressions indicated that 44% of the variance in life satisfaction was explained by perceptions of growing up slower (β =  − 1.08, p = .004) and marginally by greater perceived personal maturity (β = 0.45, p = .061).

Conclusions
Childhood cancer can influence development, with most survivors feeling that they grew up faster and were more mature than peers. Personal maturity was related to life satisfaction, with survivors of brain tumors or those who felt they grew up slower at greatest risk for lower life satisfaction. Future research and clinical practice should consider survivors’ development and maturation across the life span to promote overall well-being.
Elite and dynamic opposite learning enhanced sine cosine algorithm for application to plat-fin heat exchangers design problem
Authors: Zhang Lidong , Hu Tianyu , Yang Zhile , Yang Dongsheng , Zhang Jianhua 
Published: May 2021

AbstractThe heat exchanger has been widely used in the energy and chemical industry and plays an irreplaceable role in the featured applications. The design of heat exchanger is a mixed integer complex optimization problem, where the efficient design significantly improves the efficiency and reduces the cost. Many intelligent methods have been developed for heat exchanger optimal design. In this paper, a novel variant of sine and cosine algorithm named EDOLSCA is proposed, enhanced by dynamic opposite learning algorithm and the elite strategy. The proposed method is tested in CEC2014 benchmark and proved to be of significant advantages over the original algorithm. The new algorithm is then validated in the plate-fin heat exchanger (PFHE) optimal design problem. The comparison results of the proposed algorithm and other algorithms prove that EDOLSCA also has demonstrated superiority in heat exchanger optimal design.
Chancen und Grenzen einer ‚3-D-Ökonomie‘:
Authors: Santarius Tilman , Lange Steffen 
Published: May 2021

ZusammenfassungDigitale Technologien können eine regionale bzw. lokale Produktion durch uneingeschränkten Zugang zu Informationen und Märkten attraktiver und auch kostengünstiger machen. Zugleich ermöglichen digitale Technologien neue Kommunikationsweisen, die mehr Mitsprache, offenere Märkte und eine Begegnung von Marktteilnehmenden ‚auf Augenhöhe‘ ermöglichen. In diesem Beitrag leuchten wir die Chancen und Grenzen der Digitalisierung für eine Dezentralisierung und Demokratisierung der Ökonomie aus, veranschaulichen bestehende Potenziale anhand von zahlreichen Fallbeispielen und zeigen deren Beitrag zur ökologischen Nachhaltigkeit auf. Doch wir analysieren auch, dass diesen Potenzialen in der Realität eine historisch beispiellose Konzentration von Marktmacht in der Hand einiger weniger IT-Konzerne gegenübersteht. Nebst den Chancen zeigen wir in diesem Beitrag daher ebenfalls, aufgrund welcher Mechanismen die Digitalisierung der Ökonomie einer Dezentralisierung und Demokratisierung zuwiderlaufen kann. Abschließend stellen wir Perspektiven und Instrumente vor, wie eine ‚3-D-Ökonomie‘ – digital, demokratisch, dezentral – politisch unterstützt werden kann.
A fast sparse spectral method for nonlinear integro-differential Volterra equations with general kernels
Authors: Gutleb Timon S. 
Published: May 2021

AbstractWe present a sparse spectral method for nonlinear integro-differential Volterra equations based on the Volterra operator’s banded sparsity structure when acting on specific Jacobi polynomial bases. The method is not restricted to convolution-type kernels of the form K(x, y) = K(x − y) but instead works for general kernels at competitive speeds and with exponential convergence. We provide various numerical experiments based on an open-source implementation for problems with and without known analytic solutions and comparisons with other methods.
A Trauma-Informed, Family-Centered, Virtual Home Visiting Program for Young Children: One-Year Outcomes
Authors: Mogil Catherine , Hajal Nastassia , Aralis Hilary , Paley Blair , Milburn Norweeta G. , Barrera Wendy , Kiff Cara , Beardslee William , Lester Patricia 
Published: May 2021

AbstractMilitary-connected families face many challenges associated with military life transitions, including deployment separations. We report on a randomized controlled trial to evaluate the efficacy of Families OverComing Under Stress-Early Childhood (FOCUS-EC) delivered through an in-home, virtual telehealth platform. FOCUS-EC is a trauma-informed, family-centered preventive intervention designed to promote family resilience and well-being. Military-connected families with 3- to 6-year-old children (194 mothers; 155 fathers; 199 children) were randomized to FOCUS-EC or an online education condition. Parent psychological health symptoms, child behavior, parenting, and parent–child relationships were examined by parent-report and observed interaction tasks for up to 12 months. Longitudinal regression models indicated that FOCUS-EC families demonstrated significantly greater improvements than online education families in parent-reported and observational measures of child behavior, parenting practices, and parent–child interaction, as well as greater reductions in parent posttraumatic stress symptoms. Findings provide support for the benefit of a virtually-delivered preventive intervention for military-connected families.
Role of calcium phosphate and bioactive glass coating on in vivo bone healing of new Mg–Zn–Ca implant
Authors: Mahato Arnab , De Munmun , Bhattacharjee Promita , Kumar Vinod , Mukherjee Prasenjit , Singh Gajendra , Kundu Biswanath , Balla Vamsi K. , Nandi Samit Kumar 
Published: May 2021

AbstractPresent investigation focuses on development and detailed characterization of a new Mg alloy sample (BM) with and without coating of hydroxyapatite (BMH) and bioactive glass (BMG) by air plasma spray method. After detailed mechano-physico-chemical characterization of powders and coated samples, electrochemical corrosion and SBF immersion tests were carried out. Detailed in vitro characterizations for cell viability were undertaken using MG-63 cell line followed by in vivo tests in rabbit model for studying bone healing up to 60 days. Starting current density increases from BM to BMH to BMG indicating highest resistance towards corrosion in case of BMG samples, however BMH also showed highest icorr value suggesting slowest rate of corrosion than BM and BMG samples. Dissolution of calcium ion in case of BMH and BMG control formation of apatite phases on surface. Ca2+ ions of coatings and from SBF solution underwent reduction reaction simultaneously with conversion of Mg to MgCl2 releasing OH− in the solution, which increases pH. Viability and propagation of human osteoblast-like cells was verified using confocal microscopy observations and from expression of bone specific genes. Alkaline phosphatase assay and ARS staining indicate cell proliferation and production of neo-osseous tissue matrix. In vivo, based on histology of heart, kidney and liver, and immune response of IL-2, IL-6 and TNFα, all the materials show no adverse effects in body system. The bone creation was observed to be more for BMH. Although both BMH and BMG show rays of possibilities in early new bone formation and tough bone–implant bonding at interface as compared to bare Mg alloy, however, BMG showed better well-sprayed coating covering on substrate and resistance against corrosion prior implanting in vivo. Also, better apatite formation on this sample makes it more favourable implant.
Consistent patterns of fungal communities within ant-plants across a large geographic range strongly suggest a multipartite mutualism
Authors: Greenfield Melinda J. , Lach Lori , Congdon Brad C. , Anslan Sten , Tedersoo Leho , Field Matt , Abell Sandra E. 
Published: May 2021

AbstractIn recent decades, multipartite mutualisms involving microorganisms such as fungi have been discovered in associations traditionally thought of as bipartite. Ant-plant mutualisms were long thought to be bipartite despite fungi being noticed in an epiphytic ant-plant over 100 years ago. We sequenced fungal DNA from the three distinct domatium chambers of the epiphytic ant-plantMyrmecodia beccariito establish if fungal communities differ by chamber type across five geographic locations spanning 675 km. The three chamber types serve different ant-associated functions including ‘waste’ chambers, where ant workers deposit waste; ‘nursery’ chambers, where the brood is kept; and ‘ventilation’ chambers, that allow air into the domatium. Overall, fungi from the order Chaetothyriales dominated the chambers in terms of the proportion of operational taxonomic units (OTUs; 13.4%) and sequence abundances of OTUs (28% of the total); however a large portion of OTUs (28%) were unidentified at the order level. Notably, the fungal community in the waste chambers differed consistently from the nursery and ventilation chambers across all five locations. We identified 13 fungal OTUs as ‘common’ in the waste chambers that were rare or in very low sequence abundance in the other two chambers. Fungal communities in the nursery and ventilation chambers overlapped more than either did with the waste chambers but were also distinct from each other. Differences in dominance of the common OTUs drove the observed patterns in the fungal communities for each of the chamber types. This suggests a multipartite mutualism involving fungi exists in this ant-plant and that the role of fungi differs among chamber types.
Decolonizing transformations through ‘right relations’
Authors: Gram-Hanssen Irmelin , Schafenacker Nicole , Bentz Julia 
Published: May 2021

AbstractClimate change has been conceptualized as a form and a product of colonization. In this perspective, it becomes important to base climate change adaptation and transformation efforts on decolonizing practices and imaginaries. A central aspect of decolonization is contained in the Indigenous conceptualization of relationality. Exploring how decolonization and relationality might form the foundation for transformations research, we engage with the concept of ‘right relations’. In the context of this inquiry, we take ‘right relations’ to mean an obligation to live up to the responsibilities involved when taking part in a relationship—be it to other humans, other species, the land or the climate. We begin the paper by bringing together the literature on climate change adaptation, transformation and decolonization to show their interconnections and emphasize the need to engage with all three when talking about sustainability. Second, we invoke the idea of ‘right relations’ to address how non-Indigenous transformation researchers can further the process of decolonization as part of their research. Third, we offer insights from our own research experience with narrative practices to help exemplify how transformation researchers in all disciplines might embody ‘right relations’ centered around four characteristics: listening deeply, self-reflexivity, creating space and being in action. Embodying ‘right relations’ is a continuous process of becoming with no end point, and we do not wish to suggest that we hold the answers. Instead, we reflect on our role in this process and hope for these words to open a dialogue about how we might move towards a ‘decolonized humanity’. We suggest that willingness to be affected and altered by the process of reciprocal collaborations is key to imagining decolonial ways of being and that this in turn can be a powerful manner of generating equitable and sustainable transformations.
Enhanced or distorted wisdom of crowds? An agent-based model of opinion formation under social influence
Authors: Mavrodiev Pavlin , Schweitzer Frank 
Published: May 2021

AbstractWe propose an agent-based model of collective opinion formation to study the wisdom of crowds under social influence. The opinion of an agent is a continuous positive value, denoting its subjective answer to a factual question. The wisdom of crowds states that the average of all opinions is close to the truth, i.e., the correct answer. But if agents have the chance to adjust their opinion in response to the opinions of others, this effect can be destroyed. Our model investigates this scenario by evaluating two competing effects: (1) agents tend to keep their own opinion (individual conviction), (2) they tend to adjust their opinion if they have information about the opinions of others (social influence). For the latter, two different regimes (full information vs. aggregated information) are compared. Our simulations show that social influence only in rare cases enhances the wisdom of crowds. Most often, we find that agents converge to a collective opinion that is even farther away from the true answer. Therefore, under social influence the wisdom of crowds can be systematically wrong.
Effect of Ion Irradiation on Nanoindentation Fracture and Deformation in Silicon Carbide
Authors: Leide Alexander J. , Todd Richard I. , Armstrong David E. J. 
Published: May 2021

AbstractSilicon carbide is desirable for many nuclear applications, making it necessary to understand how it deforms after irradiation. Ion implantation combined with nanoindentation is commonly used to measure radiation-induced changes to mechanical properties; hardness and modulus can be calculated from load–displacement curves, and fracture toughness can be estimated from surface crack lengths. Further insight into indentation deformation and fracture is required to understand the observed changes to mechanical properties caused by irradiation. This paper investigates indentation deformation using high-resolution electron backscatter diffraction (HR-EBSD) and Raman spectroscopy. Significant differences exist after irradiation: fracture is suppressed by swelling-induced compressive residual stresses, and the plastically deformed region extends further from the indentation. During focused ion beam cross-sectioning, indentation cracks grow, and residual stresses are modified. The results clarify the mechanisms responsible for the modification of apparent hardness and apparent indentation toughness values caused by the compressive residual stresses in ion-implanted specimens.
Loneliness and Risk for Cardiovascular Disease: Mechanisms and Future Directions
Authors: Paul Elise , Bu Feifei , Fancourt Daisy 
Published: May 2021

Abstract
Purpose of review
In this review, we synthesise recent research on the association between loneliness and cardiovascular disease (CVD). We present evidence for mechanisms underlying this association and propose directions for future research.

Recent findings
Loneliness is related to increased risk of early mortality and CVD comparable to other well-established risk factors such as obesity or smoking.

Summary
Loneliness has been linked to higher rates of incident CVD, poorer CVD patient outcomes, and early mortality from CVD. Loneliness likely affects risk for these outcomes via health-related behaviours (e.g. physical inactivity and smoking), biological mechanisms (e.g. inflammation, stress reactivity), and psychological factors (e.g. depression) to indirectly damage health.
Spatial heterogeneity of mortality and diffusion rates determines larval delivery to adult habitats for coastal marine populations
Authors: Meyer Alexander D. , Hastings Alan , Largier John L. 
Published: May 2021

AbstractMany benthic animals begin life with a planktonic larval stage during which coastal currents may move individuals far from shore. This trait is believed to allow individuals to develop away from nearshore predators and sibling competition, based on the assumption that mortality rates are weaker offshore. However, larvae developing offshore often fail to locate suitable coastal habitats. This results in a trade-off between nearshore mortality and offshore wastage with consequences for larval delivery to adult habitats that have not been fully appreciated. We use a reaction-diffusion model to show that when the nearshore larval mortality rate is high, larval supply can vary more than 10-fold with the offshore mortality rate. If this offshore rate is weak, then larval supply is maximized by an intermediate diffusion rate or larval duration. While a low-diffusivity coastal boundary layer typically improves the larval supply by decreasing wastage, it can also reduce the larval supply by preventing individuals from exploiting low offshore mortality rates. Finally, the cross-shore structure of the mortality rate may influence the alongshore transport of larvae by determining how far offshore they reside prior to settling, and, consequently, the alongshore currents they experience. Our observations contrast with the prior argument that larval supply decreases with diffusivity and larval duration due to wastage, and challenge the widespread decision to omit cross-shore heterogeneity from studies of alongshore movement. Scenarios in which spatial variability in the mortality rate has a large effect on recruitment are important both for understanding the biological consequences of the larval stage and from a modeling perspective.
Sleep quality in students: Associations with psychological and lifestyle factors
Authors: Henrich Liv C. , Antypa Niki , Van den Berg Julia F. 
Published: May 2021

AbstractDisturbed sleep is prevalent in adult populations and has been associated with negative health outcomes. This cross-sectional study assessed how psychological and lifestyle factors relate to subjective sleep quality in university students. In a large (N = 1114) sample of Dutch university students we assessed chronotype (Morningness-Eveningness Questionnaire), depressive symptoms (Quick Inventory of Depressive Symptoms), cognitive emotion regulation styles (Cognitive Emotion Regulation Questionnaire), and substance use (caffeine, alcohol, smoking, cannabis), and analysed whether these factors were related to subjective sleep quality (Pittsburgh Sleep Quality Index). The sample was predominantly (77.8%) female, mean age 21.1 (SD = 2.9) years, and 42.8% had clinically significant poor subjective sleep quality. More eveningness (B = −.05, p = .001), more depressive symptoms (B = .31, p = .001), less use of the emotion regulation strategy ‘putting into perspective’ (B = −.06, p = .02) and smoking (B = .53, p = .02) were independently associated with poorer subjective sleep quality. More eveningness, more depressive symptoms, less use of the emotion regulation style ‘putting into perspective’ and smoking were independently associated with poorer subjective sleep quality in a large sample of Dutch university students.
Are there still indications for whole brain irradiation in 2021?
Authors: Dieckmann Karin , Herrmann Harald 
Published: May 2021

SummaryBrain metastases (BM) are the most frequent intracranial tumors in adults. About 10–20% of the patients with cancer will develop them. Historically, most of the patients with brain metastases were treated with whole brain radiotherapy (WBRT). The intention was to control the metastases and to eliminate distant micrometastases. Randomized control trials showed no difference in survival in patients with single and oligometastases treated with WBRT compared with stereotactic radiosurgery (SRS). To avoid treatment-related toxicities with neurocognitive decline, indications for WBRT are changing. High precision therapy with SRS or postoperative stereotactic treatments have become increasingly important. Only in exceptional cases is WBRT still the treatment of choice.