bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS PENERAPAN SISTEM KEUANGAN DESA (SISKEUDES) DALAM MENINGKATKAN AKUNTABILITAS KEUANGANDESA ROSOAN KABUPATEN.ENREKANG
Authors: Arham Arham , Alwi Muh , Budiman Ahmad Safari 
Published: February 2025

Penerapan Sistem keuangan dalam penelitian ini adalah untuk mengatahui tingkat pemahaman aparat desa terhadap pemanfaatan siskeudes dalam mendukung akuntabilitas keuangan Desa Rosoan Kab. Enrekang.Metode Penelitian ini menggunakan pendekatan dengan metode kualitatif, menetapkan satu objek sasaran melalui studi kasus yakni mengeksplorasi suatu kasus secara mendalam, mengumpulkan informasi dengan menggunakan berbagai prosedur pengumpulan data berdasarkan waktu yang telah ditentukan. Informan dalam penilitian ini yaitu kepala desa, sekertaris desa, bendahara desa. Metode Wawancara yang dilakukan dalam penelitan lebih berorientasi pada model wawancara tidak terstruktur wawancara tidak terstruktur dapat pula disebut dengan wawancara secara bebas. Perancanngan terhadap Aplikasi SISKEUDES secara umum telah disesuaikan dengan amanah yang dituangkan dalam Peraturan Menteri Dalam Negeri (Permendagri) Nomor 113 Tahun 2014 tentang Pedoman Pengelolaan Keuangan Desa, yang kemudian pada Tahun 2018 dirubah dengan Permendagri Nomor 20 Tahun 2018 tentang Pedoman Pengelolaan Keuangan Desa. Akuntabilitas (Accountability) sesuai dengan pemaknaan yang sering diuraikan dalam beberapa kajian teori tentunya selalu mengisiyaratkan unsur kejelasan fungsi dalam sebuah organisasi. Hasil pengamatan yang dilakukan terhadap beberapa Fitur Utama dalam Pengelolaan Keuangan Desa mulai dari Tahap Perencanaan hingga Pelaporan secara runut. dalam hasil penelitiannya bahwa Kualitas akuntabilitas keuangan setelah penerapan aplikasi SISKEUDES sangat membawa perubahan yang cukup baik bagi pemerintah Desa
PENGARUH MOTIVASI KERJA, KOMITMEN DAN BUDAYA ORGANISASI TERHADAP KINERJA PEGAWAI KANTOR BALAI PENYULUHAN PERTANIAN (BPP) KABUPATEN SOPPENG
Authors: Yusni Yusni , Ruslang T  , Sudirman Sudirman 
Published: February 2025

Hubungan antara motivasi, komitmen, dan budaya organisasi sangat erat dan berpengaruh langsung terhadap kinerja pegawai. Organisasi yang mampu mengelola ketiga faktor ini dengan baik dapat meningkatkan performa individu dan kesuksesan organisasi secara keseluruhan. Tujuan yang hendak dicapai dalam penelitian ini adalah untuk mengetahui hubungan pengaruh Motivasi kerja, Komitmen dan Budaya Organisasi terhadap Kinerja pegawai, penelitian ini menggunakan pendekatan dengan metode kuantitatif yang menjadikan semua Pegawai sebagai Responden yakni sebanyak 37 orang, sehingga model sampel yang digunakan yakni Sampel Populasi. Pengolahan data dalam penelitian ini menggunakan alat analisis SPSS (Statistical Package for the Social Sciences), sehingga dari hasil analisis hasil yang diperoleh bahwa motivasi memiliki pengaruh secara positif berpegaruh tidak signifikan terhadap kinerja pegawai pada kantor balai penyuluh pertanian (BPP) Kabupaten Soppeng, Komitmen Organisasi Memiliki Pola Hubungan Pengaruh yang Signifikan Terhadap Kinerja Pegawai Balai Penyuluhan Pertanian (BPP) Kabupaten Soppeng, Budaya Organisasi Memiliki Pola Hubungan Pengaruh yang Signifikan Terhadap Kinerja Pegawai Balai Penyuluhan Pertanian (BPP) Kabupaten Soppeng
Knowledge about Dental Caries and The DMF-T Index in Adolescents
Authors: Yuniarly Etty , Ayun Quroti , Kumalasari Dewi Erwanti , Purwati Dwi Eni 
Published: February 2025

Dental caries is one of the most common diseases found in the oral cavity. Based on the 2018 Basic Health Research, 65.5% of 12-year-old children and 67.4% of 15-year-old children experienced caries or cavities, with a national DMF-T index of 7.1. This study aims to determine the level of knowledge about dental caries and the DMF-T index among adolescents. This analytical study used a cross-sectional approach involving 90 randomly selected seventh-grade students. The results showed that 53.3% of respondents had moderate knowledge about dental caries, with an average knowledge score of 8.21. The average DMF-T index was 3.41, with 51.1% of respondents falling into the moderate category. Analysis indicated a tendency for respondents with better knowledge to have a lower DMF-T index. Additionally, 26.7% of respondents with moderate knowledge had a moderate DMF-T index, suggesting a positive relationship between the level of knowledge and oral health status. The term "moderate" reflects a sufficient but not optimal understanding of oral health and a middle-level degree of tooth decay. Further research is recommended to use longitudinal designs to analyze causal relationships, explore the influence of social factors such as family support, and develop school-based educational programs to enhance awareness and prevent caries among adolescents.
Vision-Language In-Context Learning Driven Few-Shot Visual Inspection Model
Authors: Ueno Shiryu , Hayashi Yoshikazu , Nakatsuka Shunsuke , Yamada Yusei , Aizawa Hiroaki 
Published: February 2025

We propose general visual inspection model using Vision-Language Model (VLM) with few-shot images of non-defective or defective products, along with explanatory texts that serve as inspection criteria. Although existing VLM exhibit high performance across various tasks, they are not trained on specific tasks such as visual inspection. Thus, we construct a dataset consisting of diverse images of non-defective and defective products collected from the web, along with unified formatted output text, and fine-tune VLM. For new products, our method employs In-Context Learning, which allows the model to perform inspections with an example of non-defective or defective image and the corresponding explanatory texts with visual prompts. This approach eliminates the need to collect a large number of training samples and re-train the model for each product. The experimental results show that our method achieves high performance, with MCC of 0.804 and F1-score of 0.950 on MVTec AD in a one-shot manner. Our code is available at https://github.com/ia-gu/Vision-Language-In-Context-Learning-Driven-Few-Shot-Visual-Inspection-Model.
The Evolution of Madness: A Characterization of Arthur Fleck in The Movie “Joker” (2019) by Todd Phillips
Authors: Dewi Adelia Puspita , Wijaya Mutiara Zaskia , Faisal Faisal 
Published: February 2025

This study examines the evolution of Arthur Fleck into the Joker, exploring the psychological, social, and institutional factors contributing to his transformation. Utilizing a qualitative methodology, the research analyses Arthur Fleck's character through his experiences of trauma, societal rejection, and mental health struggles. Researchers watched the movie multiple times, analysed the script, and identified relevant dialogue or words for the character. Key findings indicate that Arthur Fleck's descent into madness is shaped significantly by his childhood abuse, loneliness, and the systemic neglect he faces in Gotham City. The film serves as a critical commentary on contemporary issues surrounding mental health and societal responsibility, highlighting the urgent need for compassion towards marginalized individuals. This characterization not only reflects current societal anxieties but also emphasizes the impact of social dynamics on individual identity formation.
An Analysis of Directive Speech Acts in The Up (2009) Movie
Authors: Widianingsih Ayang Winda Sri , Mustika Rispa , Nugraha Salsa 
Published: February 2025

This research discussed about the analysis of directives type of speech act theory used in the Up (2009) movie. This research revealed the application of directives types of speech act that found in the Up (2009) movie. The document analysis approach was used in this study to gather data. The researcher chose this film as the subject of the study because it is intriguing and has numerous moral lessons. This film's themes include love, relationships between people, hope, and dreams. As the result, it was found that were 57 utterances of directive speech acts in the Up (2009) movie. From the 57 data that researcher collected, the main characters most expressed the command type of directives speech act. They are 38 commands, 3 suggestions, 3 requests, 6 orders, forbidding. Based all the data above, it can be concluded the most used directives speech act found in this data was command.
Effectiveness of a combination of acupressure and foot bath on Ankle Brachial Index (ABI) in type II diabetic patients
Authors: Deby Krissantus Adimas , Ta'adi Ta'adi , Windiarti Sri Endang 
Published: February 2025

Background: Diabetes is a chronic disease that will be suffered for life and can have an impact on complications, one of which is Peripheral Arterial Disease (PAD) which is characterized by a decrease in the value of the Ankle Brachial Index (ABI) and is the main cause of the increasing number of gangrene incidents and amputations. To prevent these complications, it is necessary to have therapy that can increase the value of the Ankle Brachial Index (ABI), which is by combining acupressure therapy and warm water foot soak (hydrotherapy).
Purpose: To analyzing the effectiveness of the combined therapy of acupressure and warm water foot soak towards Ankle Brachial Index (ABI) value in type II diabetes mellitus.
Methods: Using a quasi-experimental design with a pretest-posttest design approach with 51 participant. The participant were taken using simple random sampling technique and divided into 3 intervention groups. The first group is acupressure (n = 17), the second group is warm water foot soak (n = 17) and the third group is a combination of acupressure and warm water foot soak (n = 17). The normality test in this study was conducted using the Shapiro Wilk test, the dependent t test was used to determine any changes in each group while comparing the effectiveness of Ankle Branchial Index (ABI) values of each group using the one way anova test.
Results: The use of acupressure therapy can have an effect on the value of the Ankle Brachial Index (ABI) with a significance value of p: .000. The group receiving warm water foot soak therapy also experienced changes but the change in the Ankle Brachial Index (ABI) value was not too significant because the significance value was obtained p: 0.002. While in the group with the combination of acupressure and warm water foot bath has a significance value of p: 0.000
Conclusion: The combination therapy of acupressure and warm water foot soak provides an effective influence on the ankle branchial index with a significance value of p: 0.000 (p < 0.05) compared to warm water foot soak therapy which has a significance value of p: 0.002. (p< 0,05). By combining acupressure therapy and warm water foot soak, sclerosed blood vessels can stretch due to the effect of heat which causes vasodilation of blood vessels which has an impact on smooth blood flow and can carry oxygen and nutrients well, especially to the feet.
Phytochemical baicalin potentially inhibits Bcl-2 and VEGF: an in silico approach
Authors: Sharma Vikas , Gupta Arti , Singh Mohini , Singh Anshul , Chaudhary Anis Ahmad , Ahmed Zakir Hassain , Khan Salah-ud-din , Rustagi Sarvesh , Kumar Sanjay , Kumar Sandeep 
Published: February 2025

BackgroundThe rising prevalence of cancer cells exhibits uncontrolled growth and invasive and aggressive properties, leading to metastasis, which poses a significant challenge for global health. Central to cancer development are proteins such as NF-kB, p53, VEGF, and BAX/Bcl-2, which play important roles in angiogenesis, cell apoptosis regulation, and tumor growth.MethodologyThis in silico study evaluates the activity of six different natural as well as novel therapeutic strategies against cancer. Using a computational approach, i.e., virtual screening, molecular docking, and molecular dynamics (MD) simulations, the binding affinities and interactions of selected phytochemicals with cancer-specific proteins were analyzed. Key criteria for selection included binding affinity, molecular stability, and pharmacokinetic and toxicological properties. Post-selection, dynamics of ligand–protein interactions were further examined through MD simulations conducted using Desmond-Maestro 2020-4 on a Linux-based HP Z2 workstation, providing an insight into the conformational changes in the stability of the inhibitor–protein complexes. This was complemented by ADMET predictions to assess pharmacokinetics and toxicological profiles.ResultsOur findings reveal that out of six phytochemicals, baicalin exhibited the most promising results, with docking scores of −9.2 kcal/mol and −9.0 kcal/mol against Bcl-2 and VEGF receptors, respectively. The MD simulation (100 ns) confirmed the stability of baicalin–protein interactions, supported by hydrophobic interactions and intermolecular hydrogen bonds. The RMSD and RMSF values of baicalin exhibit an acceptable global minimum (3.5–6 Å) for p53, VEGF, and BAX/Bcl-2.ConclusionThis study highlights the potential of baicalin, a phytochemical known for anti-cancerous, anti-apoptotic, and anti-proliferative properties, as a promising candidate for cancer treatment. Further exploration and validation of its inhibitory mechanisms could open a promising avenue for therapeutic approaches in oncology.
Biomechanical analysis of spinal range of motion and intervertebral disc loadings in normal and adolescent idiopathic scoliosis models
Authors: Wang Haikuan , Ma Zhengwei , Wu Zhihua , Lin Yuanfang , Yu Jie , Qian Xin , Jian Sili , Sun Yueli , Wei Wei , Yu Xiang , Liang Ziyang 
Published: February 2025

ObjectiveWhile the Lenke classification enhances our structural understanding of adolescent idiopathic scoliosis (AIS), the biomechanical implications for spinal range of motion (ROM) and intervertebral disc (IVD) loadings remain unclear. This study aims to quantitatively explore and compare these biomechanical responses in normal thoracolumbar spines and those with various curvatures of Lenke types under pure bending conditions.MethodsThe baseline thoracolumbar finite element (FE) model was derived from a comprehensive human body FE model, validated, and calibrated against spinal responses under dynamic compression and quasi-static bending conditions. Using mesh morphing, AIS models of Lenke 1, Lenke 2, Lenke 3, and Lenke 5 were established to represent their respective spinal curvatures. Pure bending moments of ±7.5 Nm in flexion-extension, lateral bending, and axial rotation were applied to both normal and AIS models. Global spinal ROM and ROM of spinal segments T1-T6, T7-T12, and L1-Sacrum were measured under each loading condition. IVD mechanical loadings, including force, moment, and VonMises stress, were also evaluated and compared across all models.ResultsAIS models showed higher principal ROM compared to the normal model, with Lenke 2 having the highest ROM from T1-Sacrum and Lenke 3 the highest ROM from T6-12. AIS models exhibited more asymmetry in segmental ROM, particularly in the lumbar spine during lateral bending and axial rotation. IVD mechanical loadings varied significantly between normal and AIS models, influenced by spinal curvature types. AIS models had higher secondary moments and shear forces, especially under flexion-extension. The highest stress was mostly observed in the frontal IVD regions under flexion which was greatly reduced under extension. Lateral bending caused the highest stress predominantly on the same side as the loading direction in the IVD regions. The IVDs of T6-T7 and T12-L1 showed even stress distribution under axial rotation, while the right IVD regions of L5-Sacrum sustained the highest stress under right axial rotation, and the left regions under left axial rotation. In Lenke 3 and Lenke 5 models, the right (concave) regions of the T12-L1 IVD consistently sustained higher stress levels, regardless of the loading conditions applied.ConclusionThis study underscores significant biomechanical differences between normal and AIS models, revealing intricate interactions within scoliotic spines and enhancing our understanding of AIS biomechanics. These insights can aid in better diagnosis, treatment planning, and prognosis. Extension-focused therapeutic exercises may reduce stress on anterior IVDs, potentially lowering the risk of low back pain or disc herniation, while careful management of rotational exercises can help minimize stress in the lower lumbar regions.
Therapeutic potential of Laurus nobilis extract by experimental and computational approaches: phenolic content and bioactivities for antioxidant, antidiabetic, and anticholinergic properties
Authors: Altın Sevgi , Işık Mesut , Alp Cemalettin , Dikici Emrah , Köksal Ekrem , Kırboğa Kevser Kübra , Rudrapal Mithun , Rakshit Gourav , Beydemir Şükrü , Khan Johra 
Published: February 2025

IntroductionLaurus nobilis (LN), has traditional medicinal uses, and this study investigates its therapeutic potential by focusing on its phenolic content and bioactivities such as antioxidant, antidiabetic, and anticholinergic properties. Phenolic compounds play key roles in reducing oxidative stress and modulating enzymatic activities, relevant to metabolic and neurodegenerative disorders.MethodsLN leaf extracts were prepared via ethanol maceration, followed by filtration and concentration. Phenolic content was analyzed using LC-MS/MS. Antioxidant activity was assessed through ferric thiocyanate, DPPH, ABTS, and FRAP assays. Enzyme inhibition assays targeted AChE, BChE, and α-GLY, with IC50 values from dose-response curves. In silico analyses were conducted using molecular docking techniques to predict the binding mechanisms of identified phenolic compounds with the active sites of target enzymes, evaluating binding affinities and interaction profiles.ResultsVanillic acid and catechin hydrate were the most abundant phenolics. LN extract showed strong lipid peroxidation inhibition (50.53%) compared to Trolox (28.33%) and α-tocopherol (37.79%). Moderate radical scavenging and metal reduction potentials were observed. IC50 values were 2.57 µg/L for AChE, 3.78 µg/L for BChE, and 4.65 µg/L for α-GLY, indicating notable bioactivity. In silico studies confirmed strong binding affinities of phenolics to target enzymes.DiscussionLN extracts demonstrated promising antioxidant, antidiabetic, and anticholinergic activities, attributed to high phenolic content. Enzyme inhibition results suggest potential in managing metabolic and neurodegenerative disorders. In silico findings support these bioactivities, highlighting LN’s therapeutic potential.
Clinical utility of nanopore-targeted sequencing for diagnosing and treating pulmonary infectious diseases from bronchoalveolar lavage fluid
Authors: Li Gen , Sun He , Ye Yangqin , Chen Liqiong , Zhang Wenyan , Yu Shanshan , Li Qiang , Fan Lieying 
Published: February 2025

BackgroundConventional microbial testing (CMTs) for infectious pathogens faces challenges in rapid and comprehensive detection. Nanopore-targeted sequencing (NTS) is a novel approach for rapid identification of pathogens; however, clinical experience with the application of NTS is limited.MethodsWe evaluated the diagnostic value of NTS for detecting microbes in bronchoalveolar lavage fluid samples in patients with pulmonary infectious disease (PID, 137 cases), non-pulmonary infectious disease (NPID, 32 cases), or with an unknown etiology (11 cases). We performed a comparative analysis of the diagnostic efficacy of NTS and CMTs in identifying pulmonary infectious diseases and investigated the clinical utility of NTS as a diagnostic tool.ResultsNTS was significantly more sensitive than CMTs in detecting PID (86.13% vs 67.15%, P &lt; 0.01), particularly for important specific pathogens. There were no significant differences between NTS and CMTs in terms of specificity, positive predictive value or negative predictive value. Moreover, NTS (not CMTs) detected 56 microorganisms consistent with clinical presentation, indicating that NTS can provide clinicians with additional support for infection diagnosis. Additionally, prior antibiotic exposure had no influence on the detection efficiency of NTS but significantly hindered that of CMTs. After antibiotic adjustments based on NTS findings, 87.76% of patients showed significant improvement, with a notable decrease in the level of inflammatory markers (CRP, NP, PCT, WBC) post-treatment. Furthermore, NTS can significantly shorten turnaround time and provide real-time results for rapid decision making.ConclusionsNTS is more efficient than CMTs in diagnosing pulmonary infectious diseases, particularly in detecting critical or specific pathogens, providing faster and more accurate clinical information even for patients with prior antibiotic exposure. Moreover, NTS can assist clinicians in formulating more effective anti-infection strategies.
Application of autologous platelet rich plasma in Sun's procedure for acute type A aortic dissection under moderate hypothermia
Authors: Sun Kaiyue , Wei Ruyuan , Liu Zihua , Zhao Xin , Liu Kai 
Published: February 2025

BackgroundCoagulopathy and inflammatory response are the intractable complication during Sun's procedure for type A aortic dissection (AAD). This study aims to investigate the efficacy of autologous platelet rich plasma (aPRP) on the patients undergoing Sun's procedure under moderate hypothermia.MethodsA total of 372 AAD patients who underwent Sun's procedure under moderate hypothermia were divided into aPRP group (aPRP was separated before heparinization and transfused after protamine neutralization) and Non-aPRP group (without aPRP apheresis). Preoperative characteristics, intraoperative data, postoperative outcomes, and perioperative laboratory reports were collected and analyzed.ResultsThe operation time (301.1 ± 21.3 vs. 318.1 ± 29.9, P &lt; 0.001), postoperative ventilation time [25.3[19.2, 37.0] vs. 31.9[25.4, 43.1], P &lt; 0.001] and cardiac intensive care unit stay [4.8[3.5, 7.9] vs. 8.7[4.9,11.2], P &lt; 0.001] in aPRP group were significantly shorter than that in Non-aPRP group. Intraoperative blood loss (637.2 ± 24.9 vs. 908.4 ± 51.0, P &lt; 0.001), transfusion of allogeneic blood products (PLT: 2.11 ± 1.03 vs. 2.52 ± 0.83, P &lt; 0.001; Plasma: 405.6 ± 55.6 vs. 421.0 ± 61.7, P = 0.012; Cryoprecipitate: 9.7 ± 2.4 vs. 10.4 ± 1.9, P = 0.002; RBC: 422.7 ± 64.9 vs. 479.2 ± 81.0, P &lt; 0.001) and the incidence of postoperative pulmonary complications (8.2% vs. 16.2%, P = 0.027) were reduced in aPRP group. The costs of both blood products (9,202.2 ± 1,597.4 vs. 10,031.9 ± 3,471.8, P = 0.003) and the total hospitalization (243.5 ± 33.1 vs. 297.6 ± 43.5, P &lt; 0.001) were decreased in aPRP group. Furthermore, intraoperative and postoperative levels of C-reactive protein and Interleukin-6 (P &lt; 0.001) in aPRP group were lower than that in Non-aPRP group. There was no significant difference in renal, cerebral complications and hospital stay between the two groups.ConclusionApplication of aPRP in Sun's procedure reduced the perioperative blood loss and allogeneic blood transfusion, contributed to the decreased postoperative pulmonary complications and shortened intensive care unit duration. Apheresis and re-infusion of aPRP in Sun's procedure alleviated postoperative inflammation to a certain degree and was a desirable approach for AAD patients.