bluuebunny/crossref_metadata_2025_split huggingface dataset:
BRAF V600E mutation in papillary thyroid carcinoma: it’s relation to clinical features and oncologic outcomes in a single cancer centre experience
Authors: Al-Masri Mahmoud , Al-Shobaki Tawfiq , Al-Najjar Hani , Iskanderian Rafal , Younis Enas , Abdallah Niveen , Tbakhi Abdelghani , Haddad Hussam , Al-Masri Mohammad , Obeid Zeinab , Jarrar Awad 
Published: November 2021

Purpose
This study focuses on the oncologic influence of BRAF V600E mutations in a cohort of Middle Eastern papillary thyroid carcinoma (PTC) patients treated at a single centre. We tested the association of BRAF V600E mutation with papillary thyroid carcinoma at King Hussein Cancer Center.

Methods
Patients with histologically confirmed PTC who underwent surgical treatment between 2006 and 2015 were included in this study. Oncological outcomes, both short- and long-termed, were collected.

Results
A total of 128 patients (68% females) were included in this study with a mean age of 38 years (±13.8). The median follow-up period was 50 months. The BRAF V600E mutation was found in 71% of patients. The tumour size for patients with a negative BRAF V600E mutation was significantly larger in comparison to patients who tested positive for the mutation (3.47 cm vs 2.31 cm, respectively, P = 0.009). The two groups showed similar disease-free survival (DFS) rates; positive = 75% (median 43 months (0–168)) compared to 78% for the negative BRAF V600E mutation (median 38 months (3–142)) (P = 0.162, HR = 0.731) Furthermore, both groups showed similar overall survival rates, positive = 94.5% (median 56 months (0–228)) compared to 94.6% for the negative BRAF V600E mutation (median 43 months (3–157)) (P = 0.941, HR = 0.940).

Conclusion
BRAF V600E mutation had no effect on loco-regional recurrence, distant metastasis, overall survival, or DFS. These findings may be attributed to geographic variations or reflect that BRAF V600E may only serve as an indicator of poor prognosis in high-risk group as such.
Negative Effects of Endoscopists’ Fatigue on Colonoscopy Quality on 34,022 Screening Colonoscopies
Authors: Dong Zhiyu , Wang Junwen , Chen Ying , Sun Huihui , Li Bo , Zhang Qiongmei , Sun Kejing , Wang Zhenxiang , Qian Xue , Zhan Tingting , Jiang Yuanxi , Xu Shuchang 
Published: November 2021

Background and Aims: There is still considerable controversy surrounding the relationship between fatigue of endoscopists and the quality of colonoscopy. The aim of this study is to comprehensively explore the association between fatigue and adenoma detection rate (ADR) and cecal intubation rate (CIR).
Methods: The mixed effects logistic regression model was used to explore the relationship between fatigue- related factors including procedure order, session of procedures and the day of week and ADR as well as CIR.
Results: When controlling for confounders, the day of week (Monday as reference, Friday, p=0.022; weekends, p=0.015) and session of procedures (P<0.001) were significantly associated with ADR while procedure order (<5 as reference, 6-10, p<0.001; >10, p=0.001) and session of procedures (p=0.004) were independent predictors for CIR. Additionally, there was a significant downward trend on ADR and CIR with the approaching of weekends (p=0.005) and increasing procedure orders (p<0.001), respectively. In the subgroup analysis stratified by gender, age and workload intensity, significant lower ADR was found in the afternoon in all subgroups (male, p<0.001; female, p=0.005; <40 years, p<0.001; ≥40 years, p=0.020; intensity<50 per month, p=0.017; intensity≥50 per month, p<0.001) but the downward trend on ADR as the week progressed was only found in endoscopists with male gender (p=0.011), age<40 (p=0.027) and high workload intensity (p=0.003). Moreover, a significant downward trend on CIR as the procedure order increased was found in all subgroups except endoscopists with age≥40 (male, p=0.005; female, p<0.001; <40 years, p<0.001; intensity<50 per month, p=0.001; intensity≥50 per month, p<0.001).
Conclusions: Colonoscopies in the afternoon will affect ADR negatively while increasing procedure order will cause a lower CIR. Importantly, the significant negative influence of Friday and weekends on ADR was first discovered in this study. Moreover, endoscopists with female gender and advanced age (≥40) but not high workload intensity showed superiority in resistance of fatigue caused by the end of the week and increasing daily procedures.
Masking Adherence in K–12 Schools and SARS-CoV-2 Secondary Transmission
Authors: Moorthy Ganga S. , Mann Tara K. , Boutzoukas Angelique E. , Blakemore Ashley , Brookhart M. Alan , Edwards Laura , Jackman Jennifer G. , Panayotti Gabriela M. Maradiaga , Warren Todd , Pendleton Joanna , Garcés Andrew Willis , Corneli Amy , Weber David J. , Kalu Ibukunoluwa C. , Benjamin Daniel K. , Zimmerman Kanecia O. 
Published: November 2021

OBJECTIVES
Masking is an essential coronavirus 2019 mitigation tool assisting in the safe return of kindergarten through 12th grade children and staff to in-person instruction; however, masking adherence, compliance evaluation methods, and potential consequences of surveillance are currently unknown. We describe 2 school districts’ approaches to promote in-school masking and the consequent impact on severe acute respiratory syndrome coronavirus 2 secondary transmission.

METHODS
Two North Carolina school districts developed surveillance programs with daily versus weekly interventions to monitor in-school masking adherence. Safety teams recorded the proportion of students and staff appropriately wearing masks and provided real-time education after observation of improper masking. Primary infections, within-school transmission, and county-level severe acute respiratory syndrome coronavirus 2 infection rates were assessed.

RESULTS
Proper mask use was high in both intervention groups and districts. There were variations by grade level, with lower rates in elementary schools, and proper adherence being higher in the weekly surveillance group. Rates of secondary transmission were low in both districts with surveillance programs, regardless of intervention frequency.

CONCLUSIONS
Masking surveillance interventions are effective at ensuring appropriate masking at all school levels. Creating a culture of safety within schools led by local leadership is important and a feasible opportunity for school districts with return to in-person school. In our study of schools with high masking adherence, secondary transmission was low.
Personal and Social Trust in Contemporary Poland in the Light of Empirical Research
Authors: Stala Józef 
Published: November 2021

The importance of trust for the development of an individual, social relations and for the development of societies has been emphasised by social, psychological and educational theorists. Personal and social trust towards people is to a great extent bound with emotional involvement. People who are close to one another, especially relatives or friends assume that they act on similar principles. Such assumptions about personal relations make people more open, generous and optimistic. Social trust is gained in the course of various daily, professional and social experiences. Therefore, the aim of this paper is to demonstrates personal and social trust on the basis of the results of the surveys conducted by CBOS (Public Opinion Research Centre in Poland).
Psychology of the complainants
Authors: Tománek Pavol , Knošková Eliška , Drgová Jaroslava , Knošková Monika 
Published: November 2021

The article deals with the personal handling of complaints by participants in court proceedings (in rare cases it also includes those citizens who do not have such legal status as the public). The aim is to define, analyze and describe the personal characteristics of the complainants, to specify what inspires, motivates and leads them to communicate the complaint in person, directly in interaction with the court manager, and court staff by this atypical procedure before, during and after court proceedings, in addition to a written complaint. The management of complaints and the case law of complaints are based in particular on the provisions of § 62 et seq. Act no. 757/2004 Coll. on courts as amended (exceptionally also from Act No. 9/2010 Coll. on complaints as amended). On the one hand, it is a description of the basic characteristics of the applicants’ mental state, communication, behavior and conduct, and on the other hand, it is also a ­description/study of the managerial activity of the court employees. The article clarifies the peculiarity of the above-mentioned method used to settle the parties in dispute before the courts, but outside the court proceedings one finds that the complainants are absent from the social, health and legal counseling service provided by state or private sectors before the sitting. These areas are to some extent, eventually more or less covered by courts of the Slovak Republic by personally accepting and addressing the complainants. The public is generally unaware of this, but the professionals consider/understand this activity as a protopype (basis) of family court formation or a return to classical counseling from the beginning of the 21st century.
The Presence of Children on the Market of Commercial Sexual Services as a Response to Deviant Needs of Adults
Authors: Wójcik Magdalena 
Published: November 2021

Sexual needs are one of the essential needs of the human person. At least, in the course of the socialization the individual should aspire to getting the sexual satisfaction in the way adapted for the value and social norms. An unremitting demand for sexual services is an essential problem of the modern world as its demand is leading to this being provided by children.
Ius patronatus as viewed by Edward Rittner
Authors: Kantor Robert 
Published: November 2021

Patronage can be defined as a group of privileges and duties granted by ecclesiastical authorities to the faithful who founded a church, chapel or benefice and to those who acquired this right from them. This is how Prof. Edward Rittner, the Rector of the University of Lviv, understood this concept. This article, entitled “Ius patronatus as viewed by Edward Rittner”, presents the notion of patronage itself, as well as related issues, such as: the ways of patronage acquisition, the possibilities of patronage transfer, the content of ius patroantus and finally the ways of patronage expiration. This article is based on Prof. Rittner’s lecture contained in his textbook “Prawo kościelne katolickie” (in English: Catholic Ecclesiastical Law), volume I, fourth edition from Lviv dated 1912.
Arrival times of P waves and upper mantle structure
Authors: Tryggvason Eysteinn 
Published: November 2021

ABSTRACT
Residuals of arrival times of P waves, as given in the International Seismological Summary for Kiruna, Sweden, Reykjavik, Iceland, and Scoresbysund, Greenland, were studied in order to detect upper mantle anomalies. The Kiruna arrivals were systematically too early, with a mean residual of −1.4 seconds, while the mean Reykjavik residual was +1.3 seconds. The difference in mean residual was 2.7 seconds with a standard error of about 0.5 second. The mean residual at Scoresbysund was −0.4 second.
It is assumed that there is a depth D below which the mantle is homogeneous. The difference in mean residuals at the stations is assumed to be caused by different wave velocities at depths less than D in the vicinities of the stations. If it is assumed that the P-wave velocity in the upper mantle is constant down to a depth D below each station, this depth can be computed. This velocity is known from other data to be 8.36 km/sec below Kiruna and 7.4 km./sec. below Reykjavik. If only earthquakes at distances from 20° to 39° were used, D is determined to be 246 ± 36 km. (standard error). Earthquakes at distances 40° to 59° give D = 177 ± 25 km., at distances 60° to 79° give D = 234 ± 14 km., and at distances 80° to 99° give D = 281 ± 20 km. The most probable value of D is thus about 240 km. below the earth's surface, with a standard error of about 40 km. In the vicinity of Scoresbysund the upper mantle velocity is found to be about 8.0 km./sec., using the same assumption.
El cuidado de sí y la figura del Pedagogo
Authors: Pérez Sánchez Yolotzin 
Published: November 2021

El cuidado de sí como noción recuperada de la antigüedad griega se planteó como interés principal para estudiar las prácticas del pedagogo, sin embargo, estudiar el cuidado de sí comprende otras dos nociones importantes, la epimeleia heautou (inquietud de sí) y la tekhne tou biou (arte de vivir). Así que para remitir a ellas, se siguió un estudio teórico y metodológico del trabajo de Michel Foucault, refiriendo a la última parte de sus investigaciones, donde se puede encontrar un interés fascinante por el cuidado de sí y la constitución ética del sujeto.
El objeto de la investigación es la práctica de cuidado de sí en las prácticas del pedagogo, lo que posibilitó primero, comprender el cuidado de sí a partir de la subjetividad y la relación sujeto-verdad; segundo, comprender y vincular la ética y estética de la existencia a partir de la tekhne tou biou, el gobierno de sí y la parrhesía; y, por último, estudiar y tener un primer acercamiento a la genealogía del pedagogo.
Para pensar al pedagogo junto al cuidado de sí, se sugirió un modo de subjetivación distinto, es decir, un modo distinto de relacionarse con la regla y la norma, remitiendo a su práctica desde su objeto de interés y deseo: el cuidado de los otros. Bajo este entendido, la práctica del educador, entendida desde la antigüedad griega, y la práctica pedagógica se muestran paralelas, no obstante, en esta última se desarrollan una serie de técnicas y ejercicios que lo sitúan y lo constituyen de otro modo, un modo que ni aquí ni en ningún otro lugar debe prescribirse, pues al tratarse de la tekhne tou biou, no hay reglas impuestas ni códigos a los que sujetarse rigurosa y obligatoriamente para constituirse como sujetos estéticos.
CAPACIDADE ELICITORA DOS EXTRATOS DAS FOLHAS DE Aristolochia trulliformis
Authors: Barreiros de Souza Ester , Dos Santos Castro Marleilde , Oliveira Guilherme Eduardo , Rodrigues dos Santos Gil , Pereira de Souza Ferreira Talita , Holzbach Juliana Cristina 
Published: November 2021

A espécie Aristolochia trulliformis que pertence à família Aristolochiacea, é conhecida popularmente como jarrinha ou cipó-mil-homens e as folhas da espécie são utilizadas para tratar de problemas estomacais. O objetivo deste trabalho foi obter os extratos de diferentes polaridades das folhas de A. trulliformis, verificar possíveis atividades alelopáticas causadas pelo extrato metanólico utilizando sementes de alface da espécie Lactuvia sativa e analisar a síntese de substâncias indutoras de resistência a doenças em soja e sorgo. As massas obtidas nos processos de extração foram 2,0 g, 5,2 g, 7,3 g, para os extratos hexânico, acetônico e metanólico, respectivamente. Os resultados obtidos no teste de alelopatia mostraram que concentrações superiores a 100 µL.mL-1, para raízes, e 2000 µL.mL-1, para plântulas, inibem seus desenvolvimentos. Já no teste de fitoalexina o extrato metanólico induziu efetivamente a produção das biomoléculas principalmente em sementes de sorgo.
Minimally Invasive Percutaneous Fasciotomy in Lumbar Paraspinal Compartment Syndrome
Authors: Kim Daniel C. , Padhye Kedar , Schwender Eric , Shafa Eiman 
Published: November 2021

Case:
Lumbar paraspinal compartment syndrome (LPCS) is a rare but potentially catastrophic pathology caused by increased intracompartmental pressures leading to potential ischemic necrosis of muscle, local denervation, and complications of rhabdomyolysis. A combination of unique clinical history and examination findings, laboratory findings, and radiologic imaging help in diagnosis.

Conclusion:
Early detection and intervention with minimally invasive percutaneous fasciotomy can minimize local soft tissue trauma while providing extensive fascial release with good clinical outcomes. Radiographic follow-up in this case suggests that the muscle at risk in LPCS can be spared with early surgical intervention.
Congenital Pseudarthrosis of the Tibia Associated With Cleidocranial Dysostosis
Authors: McClure Philip K. , Franzone Jeanne M. , Herzenberg John E. 
Published: November 2021

Case:
We describe a case of 2 individually rare diseases existing comorbidly in the form of congenital pseudarthrosis of the tibia (CPT) coincident with cleidocranial dysostosis and provide a review of the literature, including the sole preexisting documented coincidence.

Conclusion:
Understanding, treatment, and surgical protocol of CPT have changed considerably since this comorbidity was last reported. Updates include synostosis, periosteal grafting, the use of bone morphogenetic protein, and bisphosphonates. Our case varies from the previous in associated disorder and family history. The relationship between CBFA1 and RUNX2 genes may hold the key, but further study is needed.
Tension Hydrothorax After Attempted Arthroscopic Fixation of Greater Tuberosity Fracture in a Trauma Patient
Authors: Diltz Zachary R. , Baessler Aaron M. , Brolin Tyler J. 
Published: November 2021

Case:
We report the case of a 27-year-old man who presented after a 30-foot fall with a hemopneumothorax, multiple rib fractures, and left shoulder dislocation with greater tuberosity fracture. During attempted arthroscopic repair, the patient developed pulseless electrical activity arrest as the result of intraoperative tension hydrothorax. We hypothesize that this was caused by a traumatic soft-tissue communication to his shoulder joint from the apex of his lung.

Conclusion:
To our knowledge, this is a unique and unreported complication of shoulder arthroscopy and should increase awareness about possibly delaying surgery in the setting of significant soft-tissue trauma.
Kherzet Youcef Mine Flooding of 2nd June 1990 Revisited (Northeastern of Algeria) Origine and Hydrogeological Consequences
Authors: Souhila CHEDDAD , Abdelhamid Haouchine 
Published: November 2021

Abstract
This work is part of the hydro geological study of the Kherzet Youcef deposit. The polymetallic deposit of Kherzet Youcef is known since the beginning of the 20th century. It is known by the exploitation of Lead and Zinc ore. It is located 50 Km southeast of Setif (North-eastern Algeria) and 5.5 Km west of Ain Azel. Mineralization can be described by some ore bodies (about 25). The thickness variate from a few centimeters up to 3 m. These bodies are located on the layers of dolomite and dolomitized marl and along the Kherzet Youcef fault. The geological reserves of Zinc and Lead ore are of the order of 1.6 million tons. This ore has a Pb content of 3.6% and Zn content of 18.4%. The projected annual exploitation was 100 thousand tons per year. Hydro geological studies carried out successively (1973-1977) and (1981-1983) revealed the existence of an aquifer system located west of the Kherzet Youssef fault. It is characterized by the presence of Karts and by strong cracking due to local brittle tectonics. These two characteristics define the filtration and storage capacity of very abundant groundwater. This groundwater represented a major handicap for mining in view of the large amounts of water that required the installation of major pumping and drainage devices. The Kherzet Youssef mine has experienced frequent flooding in the past at a time when technology could not pump efficiently. It caused the mine to close several times. In June 1990, the mine experienced a flood of great magnitude that has never been observed and despite the large installed means of pumping, this 'water costled to the total drowning of the mine, the death of 19 workers and the stoppage of the exploitation of this deposit since. Pitting attempts were carried out with a pumping capacity of 1100 m3/h, then 1800 m3/h but without success. The interpretation of the drawdown data and field observations made it possible to conclude that this accident was only the result of the general destabilization of the massif. Our complementary work by geophysical prospecting made it possible to represent the configuration of the underground layers and demonstrate the hydrodynamic communication between the two East and West compartments of the deposit.
Global Mean Sea Level Variation On Interannual-Decadal Timescales: Climatic Connections
Authors: Liao Jennifer Ting-Juan , Chao Benjamin Fong 
Published: November 2021

Abstract

We investigate the influences of the climatic oscillations on global mean sea level (GMSL) on interannual-decadal timescales. We conduct correlation analyses on the GMSL-ID time series, which is obtained upon removing numerically the long-term trend and seasonal variations from satellite radar altimeter data since 1992, with several climatic oscillations represented by their respective meteorological indices, including El Niño-Southern Oscillation (ENSO), Pacific Decadal Oscillation (PDO), Atlantic Multidecadal Oscillation (AMO), Arctic Oscillation (AO), Antarctic Oscillation (AAO). From the time-domain correlation and frequency-domain coherence, we find: (i) High correlation between GMSL and ENSO on timescales longer than 1.5 years, especially w.r.t. the Central-Pacific type of El Niño, evidently related to changes in dynamics of the ocean mixed layer and in land-sea distribution of precipitation. (ii) Moderate correlations of GMSL with PDO and AMO, respectively on timescales of over 4 years and 2-10 years, where AMO’s correlation peaks at 8 months earlier in phase than GMSL. (iii) Weak correlation of GMSL with AO implying exchanges of the Arctic water with other oceans even though the altimetry data do not include Arctic sea,. (iv) Practically no correlation between GMSL and AAO. Finally, we least-squares fit the above five indexes to GMSL to assess the relative contribution of each oscillation in causing the interannual GMSL variations, which would lead to a better understanding of the GMSL under the on-going climate changes.
Assessment of Renewable Electricity Policy for Sustainable Electricity Generation in Nigeria
Authors: IYABO OLANRELE 
Published: November 2021

Abstract
Nigeria commits to fast track the integration of renewables in electricity generation by enacting a 2015 National Renewable Energy and Energy Efficiency Policy (NREEEP). Thus, this policy briefing assesses the effect of the policy, and other socioeconomic factors, on the deployment of renewable electricity generation. The preliminary findings show that renewable energy policy has little effect in facilitating renewable electricity integration in Nigeria due to lack of political will and its adverse effect evident in the non-implementation of incentives like feed-in-tariffs and a zero import duty waiver. Second, increased fossil fuel consumption impedes the deployment of renewable electricity due to the hydrocarbon endowment and its subsidization. The domestic financial market development in Nigeria does not also support the deployment of renewable electricity that requires long-term finance. It requires a political will to strengthen the legal and institutional framework for a sustainable electricity generation deployment. It is also pertinent to consider the total removal of fossil fuel subsidies for renewable electricity integration.