bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and peculiarities of clinical signs of periodontium diseases in patients with chronic pancreatitis
Authors: N. V. Chornii  
Published: December 2021

This paper presents the results of a study of periodontal status in patients with chronic pancreatitis. The study established the high prevalence of periodontal disease in individuals with chronic pancreatitis.The disease manifested itself in a form of generalized chronic catarrhal gingivitis and chronic generalized periodontitis of mild and moderate degrees.
State of some indicators of immunocytokine profile in young people with bronchial asthma
Authors: G. I. Shumko  
Published: December 2021

The condition of some indicators of immunocytokine profile in young adults with bronchial asthma has been studied. It showed an increasing level of interleukin-1b, tumor necrosis factor-a and immunoglobulin E in the blood. Factors which support the progression of asthma in young adult are the violation of immunocytokine profile due to the increasing level of interleukin-1b, tumor necrosis factor-a, which is accompanied by an increase of blood immunoglobulin E.
Analysing the influence of factors of birth cohort maturing on geographical distribution of disability risks due to cardio-vascular diseases
Authors: V. P. Klymeniuk  , O. M. Ocheredko  
Published: December 2021

We investigated the local regularities of disability incidence due to cardiovascular diseases in Zhytomyr oblast over 1999-2008 by strip-split-plot design. By using geographical mixed model we ascertained the peculiarities of disability distribution among cohorts, age groups and time periods (APC). Data analysis was carried out on the base of hierarchical nonlinear mixed model. Results bear witness to enhanced local heterogeneity in disability rates due to irregularity in distribution of APC factors. Each APC factor rendered significant modification to geographical distribution of disability rates.
Arterial hypertension, dysfunction of kidneys and osteoarthrosis in overweighted patients
Authors: T. O. Ilashchuk  , N. V. Shvets  , T. V. Zakharchuk  
Published: December 2021

Analysis of influence of high blood pressure over the functional state of kidneys in patients with arterial hypertension and concomitant osteoarthrosis, and overweight with estimation of efficiency of omega of -3-polyunsaturated fatty acids application has been carried out in the review of literature. Hormones and cytokines produced by fatty tissues cooperate at the level of the neuronal systems, causing overactivaty of sympathetic nervous system, increase of blood pressure level in case of excessive weight. Unity of pathogenesis of the investigated pathological processes is shown, for treatment of which omega-3-polyunsaturated fatty acids prescription is rational; that will become a basis of perfection of pathogenetically reasonable and inculcated in medical practice approach for treatment of metabolic disorders.
Clinical hemodynamic effects of fructose-1,6-diphosphate and phosphocreatinum in patients with acute coronary syndrome
Authors: A. K. Abbasov  , B. A. Alyavi  , Z. T. Sabirjanova  , A. U. Azimov  , N. U. Kayumov  , F. Z. Ariphodjaeva  , B. R. Salikhov  , Sh. I. Azizov  
Published: December 2021

One of the promising areas of treating cardiovascular diseases is the use of drugs with metabolic action. Metabolic drugs have not only the ability to improve myocardial energy metabolism, but also strong antioxidant properties.
Prevalence of hyperhomocysteinemia, dyslipidemia and subclinical inflammatory syndrome in patients with repeated ischemic attack and stroke
Authors: G. V. Bezsmertna  
Published: December 2021

The prevalence of metabolic disorders in homocysteine, lipids and subclinical inflammatory syndrome were studied in 153 patients with primary and recurrent ischemic stroke. The severe course of cerebrovascular disease is associated with metabolic disorders, especially with hyperhomocysteinemia. In patients with recurrent ischemic attacks and strokes, as compared with the primary ones, high levels of homocysteine, lipids and inflammatory markers are more frequently diagnosed and the proportion of individuals with hyperhomocysteinemia, hypercholesterolemia and aberrant levels of interleukin -6 increases.
The process of phagocytosis in the antigenic load and their correction
Authors: B. M. Verveha  
Published: December 2021

Using experimental data an analysis of the changes of the oxygen-dependent and oxygen independent enzymatic processes in neutrophilic granulocytes of rats that had simulated chronic immune complex process with placental polybiolinum correction has been carried out. It was established, that under conditions of chronic immune complex process enzymatic processes in neutrophilic granulocytes get activated. Application of placental polybiolinum restored grasping ability of neutrophils and reduced the activity of the oxygen-dependent and oxygen independent enzymatic processes in neutrophilic granulocytes, which in turn leads to the normalization of the integration processes.
Effect of Lipin as a basis of liposomal Lipoflavon on the functional state of kidneys in rats under a model of pathology
Authors: O. M. Horoshko  
Published: December 2021

The impact of Lipin as part of Lipoflavon on renal function in animals under conditions of glycerol model of nephropathy was analysed. As a result, it was determined that after a single application, Lipoflavon can improve the renal function under conditions of acute renal failure. At the same time Lipin in equivalent dose of that in Lipoflavon does not influence the renal function.
Features of cytokine adjusting malfunction for patients with gout dependent upon the stage, level of comorbidity and treatment
Authors: O. I. Doholich  , O. I. Voloshyn  
Published: December 2021

It has been established that in patients with gout, dependent on the stage of its development and intensity of polymorbidity and comorbidity adjustings of chronic inflammatory process progress and cytokine chain gets disturbed. Attainment of clinical remission of articular syndrome in patients with gout and significant expression of imbalance of proand anti-inflammatory cytokines is indicative of pathogenic "contribution" of comorbidity pathological conditions, especially metabolic syndrome, to support the chronic inflammatory process.
The investigation of changes of indexes of calcium metabolism in rats with decreased function of thyroid gland under the influence of physical loading
Authors: N. G. Pobigun  
Published: December 2021

The changes of indexes of calcium-phosphorus metabolism and data of densitometry of bone tissue in experimental hypofunction of thyroid gland in conditions of action of physical loading have been revealed. In these conditions worsening of thyroid status was accompanied by the increase of content of inorganic phosphorus and albumins in blood serum on the background of increase of bone mineral density in the area of greater trochanter of femurs in comparison with the similar indexes in animals with hypothyroid dysfunction.
Investigation of relationship between the level of cytokines and clinical parameters of patients with generalized periodontitis under the influence of Zinaxin
Authors: S. S. Romanyshyn  , V. I. Gereluk  , O. P. Kobryn  , N. I. Kukurudz  , L. I. Kurbatova  , N. M. Pavelko  , G. S. Kropelnitska  
Published: December 2021

As a result of a comprehensive clinical and laboratory research the pathogenetic role of cytokine imbalance in the pathological process formation in the periodontal tissues was established. Correlation analysis of cytokines’ content in gingival and oral fluid of patients with generalized periodontitis and data of clinical indicators of periodontal tissues showed that there is a strong direct connection between pro-inflammatory cytokines and clinical parameters.
Lipid peroxidation and oxidative modification of proteins in non-alcoholic steatohepatitis, combined with chronic obstructive pulmonary disease
Authors: T. P. Tsyntar  
Published: December 2021

The examination of 15 NASH, 20 patients with chronic obstructive pulmonary disease and 20 patients with non-alcoholic steatohepatitis combined with chronic obstructive pulmonary disease showed a significant increase in the intensity of lipid peroxidation and oxidative modification of proteins for comorbidity.
Advances and problems of teaching physiology to foreign students according to credit-module system
Authors: S. V. Konovalov  , O. V. Bohomaz  
Published: December 2021

The article generalizes the experience of Physiology teaching to foreign students at Pirogov Vinnytsia National Medical University according to credit-module system. The academic performance results of international medical students (with Russian as a medium of teaching) at the Normal Physiology department for six-year period (2008-2013) were analyzed.
XRF analysis as a tool for identification of research at the present level gunshot injuries
Authors: Mishalov Volodymyr , Khokholieva Tamara , Petroshak Oleksandr , Hurina Oksana , Chykhman Yaroslava , Hrynchyshyna Oleksandra , Mykhailenko Oleksandr 
Published: December 2021

Optical Spectroscopic techniques are widely used in practice, despite the high sensitivity and wide range studied chemical elements, have the drawback such as sample preparation, which is possible only if the destruction of the object of research. Non- destructive method of investigating the elemental composition of layers of metals and other GSR is micro-XRF, but investigated the possibilities of modern equipment is not enough.
Objective. The study was to identify the distribution of chemical elements in damages simulators clothes at experimental shots from firearms through.
Methods. The objects of study were damaged clothing (patches of skin, which made jacket). Was used micro XRF spectrometer
«M4 TORNADO» manufactured by Bruker (Germany).
Results. Technical features and software spectrometer «M4 TORNADO» provides new opportunities for laboratory diagnosis of various chemical elements in the tissues of biological and non-biological origin, including gunshot residue (GSR). The advantages of micro-XRF method are similar in topography mapping capabilities that individual elements and their combinations. In analyzing the nature of the distribution of elements on maps derived researcher has the opportunity to interpret the intensity of the character and background layers of the concentrations of elements that creates the preconditions for refusing the study of the control sample (material outside the target area of damage).
Conclusion. new opportunities for laboratory diagnostics GSR by using micro- XRF.
Indelible disfigurement of face - forensic and legal aspects
Authors: Holubovych Leonid , Holubovych Andrii , Holubovych Petro , Zubko Mariia , Kurtiev Anatolii 
Published: December 2021

Fleeting changes in economic, political and social life dictate the need for changes in the legal field, where the work is not only lawyers but also forensic medical experts, the main job is to help the judicial and investigative authorities in establishing the truth in specific cases where crimes against life, health, honor and dignity. In this article the difficulties with which forensic medical expert has faced during determining the degree of injuries under the criteria of "indelible disfigurement of face" and suggested ways to resolve the conflicts are analyzed.
Objective. Analyzation of forensic and legal approaches to solve questions and to find ways to resolve conflicts.
Conclusion. We are convinced that no specialist whether the forensic medical expert, an investigator or a judge can not single-handedly solve the problem of disfigurement of face, therefore consider it appropriate to solve the research question within the commission or a comprehensive forensic examination, a fundamental part of which is determined by the person that appointed it to the list of specialists who have the necessary aesthetic ideas to solve the issue on its merits. Order or decision of the representatives of the law enforcement bodies confirm the powers of the Commission within the issues to be addressed and, accordingly, take the possible claims, by the exit of members of the expert committee for the limits of its competence.
Despite the fact that our opinion may not be absolutely perfect, this publication we invite experts of forensic experts and lawyers to fruitful discussions and address the issues raised.
Post-mortem interval estimation by laser-induced fluorescence of polycrystalline cerebro-spinal fluid films images
Authors: Garazdiuk Marta 
Published: December 2021

There are many new optical diagnostic methods (photometric, polarization and correlation techniques) of biological tissue structure assessment, which are the most perspective in post-mortem interval determination.
The purpose of the work. Development and testing of the two-dimensional Stokes-polarimetric mapping of biological layers own fluorescence to evaluate accuracy of the post-mortem interval (PMI) assessment using statistical analysis of postmortem changes dynamics of the coordinate distributions values of polycrystalline films of liquor (PFL) images laser-induced fluorescence polarization intensity (LIFPI).
Materials and methods. Objects of investigation are PFL, taken in 72 corpses with accurately known time of death and 20 healthy volunteers. The cause of the death was cardiovascular accident. Coordinate distributions of LIFPI image values were determined for each sample of PFL in the optical arrangement of the Stokes polarimeter in short-range spectrum of optical radiation.
The value of statistical points 1 - 4 th order was perfomed for each two-dimensional distribution of PFL images LIFPI values. Statistical processing of the calculated values of set of points that characterize the LIFPI distributions was carry out. The depending on the time change of the most sensitive points of statistical values were built.
Results and conclusions. Two-dimensional Stokes-polarimetric mapping distributions LIFPI of PFL images may be used in determination of the PMI. Statistical points of the first and fourth order are the most sensitive PFL optical values to evaluate postmortem changes by short-range fluorescence.
Reflection on supporting offshore international students during the pandemic
Authors: Choo Liyun Wendy 
Published: December 2021

Teaching is usually considered a caring profession, yet care in higher education settings is rarely studied. In this reflective piece, I draw on my experiences supporting offshore international students during the pandemic to highlight that maternal, calculated and neoliberal care are not the only enactments of care possible in higher education setting. I propose that communal forms of caring teaching based on recognition and dialogic relationship with students offer tertiary educators the opportunity to put the heart back to the neoliberal university.
Malaysia’s Healthcare Expenditure: ARDL Bound Test
Authors: Mohd Nasir Noormahayu Binti , Nasir Zarul Azhar , Abdullah Fahami Norasyikin , Ahmad Kusairee Muhammad Adidinizar Zia , Ramli Khalijah 
Published: December 2021

This study aims to analyse the relationships between income level, education expenditure, inflation, and ageing population towards health expenditure in Malaysia over the period of 1997 until 2017. This study employs Autoregressive Distributed-Lag (ARDL) Bound test in determining the long-run empirical relationships between all independent variables and healthcare expenditures in Malaysia. The findings show the existence of long run cointegration between healthcare expenditure inflation, income level, and the government’s education expenditure. The results confirmed that all independent variables have positive long run relationships, except the ageing population that displays a negative relationship in influencing healthcare expenditure in Malaysia. The regression result of GDPP shows income elasticity value of 0.690, reflecting the necessity of healthcare expenditure. The outcome of the paper hopes to provide insights on the importance of healthcare expenditure for the development of this country, especially on its economic fronts.
Improvement of Pre-Service Teachers' Practical Knowledge and Motivation about Artificial Intelligence through a Service-learning-based Module in Guizhou, China: A Quasi-Experimental Study
Authors: Pu Song , Ahmad Nor Aniza , Md. Khambari Mas Nida , Keng Yap Ng , Ahrari Seyedali 
Published: December 2021

Abstract. The purpose of this study is twofold: 1) to develop a service-learning-based module training artificial intelligence (AI) subject (SLBM-TAIS), and 2) to evaluate the effect of SLBM-TAIS on pre-service teachers’ (PSTs’) practical knowledge and motivation, as well as primary school students' attitude towards AI in China. Participants of this study comprised 60 PSTs and 107 primary school students. The experimental research in this study followed the quasi-experimental non-randomized pre-test and post-test control group design. The PSTs were divided into experimental and control groups, and the primary school students followed the same grouping. The PSTs in the experimental group taught AI subjects to the primary school students in the experimental group, while the PSTs in the control group taught AI subjects to the primary school students in the control group. The results of the study showed that SLBM-TAIS was effective in training PSTs to teach AI subjects to primary school students. Furthermore, the SLBM-TAIS developed in this study offered a unique technique for training PSTs and primary school students that could increase PSTs' practical knowledge and motivation, as well as primary school students' attitudes toward AI. The findings from this study are important in the field of educational psychology, and its contribution has several theoretical and practical implications.

Keywords: Attitude; artificial intelligence; pre-service teachers; primary school students; practical knowledge; motivation
Assessing Preschool Teachers’ Challenges and Needs for Creativity in STEM Education
Authors: Amran Muhammad Syawal , Abu Bakar Kamariah , Surat Shahlan , Mahmud Siti Nur Diyana , Mohd Shafie Amirul Anwar Bin 
Published: December 2021

Abstract: Creativity in teaching is important in order to ensure children are engaged in learning Science, Technology, Engineering and Mathematics (STEM). However, previous research has claimed creativity in learning STEM for children is not adequately supported by teacher in classroom due to the lack of preparation, content knowledge and skills. This study aims to assess the needs and challenges of promoting creativity in STEM education. In this study, preschool teachers (n= 22) were interviewed as they are the key informants who are involved in STEM education. The semi-structured interviews were analysed using qualitative content analysis and were qualitatively coded. Results illustrate that there are several distinctive themes identified as described by the participants when discussing the needs and challenges of implementing integrated creativity skill in STEM education as well as the support that would be most helpful in overcoming them. The results highlighted a huge gap between creativity knowledge and the implementation of creativity in STEM education. Participants also provided specific support needed to integrate creativity in STEM education. Preliminary findings suggest that many teachers are interested in integrating creativity skills in STEM education. This research sheds light on the needs and challenges for professional pre-school teachers by providing them pedagogical module as well as professional training to promote creativity in teaching STEM

Keywords: Creativity Skills, Needs and Challenges, STEM
El turismo rural de base comunitaria como política pública en los departamentos de Humahuaca y Valle Grande (Jujuy, Argentina)
Authors: Mancini Clara Elisa , Cayo Gisela Paola 
Published: December 2021

El presente trabajo analiza el caso de la aplicación del proyecto de Corporación Andina de Fomento (CAF)– Banco de Desarrollo de América Latina: “Empoderamiento socioproductivo de comunidades vulnerablesen Jujuy (2018-2020)”. La finalidad de dicho proyecto radica en el desarrollo de emprendimientos de Turismo Rural Comunitario (TRC) entre comunidades originarias del Zenta, en los Departamentos de Humahuaca y de Valle Grande (Jujuy, Argentina). En muchos casos se han cuestionado los impactos del auge del turismo y la patrimonialización por ser los desencadenantes de la expansión urbana, la periferización de las principales ciudades quebradeñas y la ocupación de áreas de riesgo hídrico. El TRC intenta ubicarse como la contracara de ese turismo, y promueve el desarrollo rural y apoya las comunidades para que no tengan que trasladarse desde sus regiones hacia las áreas centrales en busca de empleo o para mejorar la calidad de vida. Con este fin, se analizarán los elementos constitutivos de la política pública. Luego, se discutirán las características del territorio de la Quebrada de Humahuaca, y de la región del Zenta en particular, los procesos de transformación recientes. Finalmente, se evaluará la política en relación con las implicancias en el territorio.
Keratometry, biometry, and prediction of intraocular lens power in adult tigers (Panthera tigris)
Authors: Owens Cameron D. , Michau Tammy M. , Boorstein Justin , Wynn Elizabeth R. , McMullen Richard J. 
Published: December 2021

Abstract

OBJECTIVE
To calculate the necessary pseudophakic intraocular lens (IOL) power to approximate emmetropia in adult tigers.

ANIMALS
17 clinically normal adult tigers.

PROCEDURES
33 eyes of 17 clinically normal adult tigers underwent routine ophthalmic examination and B-scan ultrasonography while anesthetized for unrelated procedures. Specific ultrasound data (globe measurements and corneal curvature) and estimated postoperative IOL positions were utilized to calculate predicted IOL power by use of Retzlaff and Binkhorst theoretical formulas. Applanation tonometry and refraction were also performed.

RESULTS
Mean ± SD axial globe length was 29.36 ± 0.82 mm, preoperative anterior chamber depth was 7.00 ± 0.74 mm, and crystalline lens thickness was 8.72 ± 0.56 mm. Mean net refractive error (n = 33 eyes) was +0.27 ± 0.30 diopters (D). By use of the Retzlaff formula, mean predicted IOL power for the postoperative anterior chamber depth (PACD), PACD – 2 mm, and PACD + 2 mm was 43.72 ± 4.84 D, 37.62 ± 4.19 D, and 51.57 ± 5.72 D, respectively. By use of the Binkhorst equation, these values were 45.11 ± 4.91 D, 38.84 ± 4.25 D, and 53.18 ± 5.81 D, respectively. Mean intraocular pressure for all eyes was 14.7 ± 2.69 mm Hg.

CLINICAL RELEVANCE
The calculated tiger IOL was lower than reported values for adult domestic felids. Further studies evaluating actual PACD and pseudophakic refraction would help determine the appropriate IOL power to achieve emmetropia in this species.