bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validating International Classification of Disease 10th revision algorithms for identifying influenza and respiratory syncytial virus hospitalizations
Authors: Hamilton Mackenzie A , Calzavara Andrew , Emerson Scott D , Kwong Jeffrey C 
Published: November 2021

Objective: Routinely collected health administrative data can be used to efficiently assess disease burden in large populations, but it is important to evaluate the validity of these data. The objective of this study was to develop and validate International Classification of Disease 10PthP revision (ICD -10) algorithms that identify laboratory-confirmed influenza or laboratory-confirmed respiratory syncytial virus (RSV) hospitalizations using population-based health administrative data from Ontario, Canada.
Study Design and Setting: Influenza and RSV laboratory data from the 2014-15 through to 2017-18 respiratory virus seasons were obtained from the Ontario Laboratories Information System (OLIS) and were linked to hospital discharge abstract data to generate influenza and RSV reference cohorts. These reference cohorts were used to assess the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the ICD-10 algorithms. To minimize misclassification in future studies, we prioritized specificity and PPV in selecting top-performing algorithms.
Results: 83,638 and 61,117 hospitalized patients were included in the influenza and RSV reference cohorts, respectively. The best influenza algorithm had a sensitivity of 73% (95% CI 72% to 74%), specificity of 99% (95% CI 99% to 99%), PPV of 94% (95% CI 94% to 95%), and NPV of 94% (95% CI 94% to 95%). The best RSV algorithm had a sensitivity of 69% (95% CI 68% to 70%), specificity of 99% (95% CI 99% to 99%), PPV of 91% (95% CI 90% to 91%) and NPV of 97% (95% CI 97% to 97%).
Conclusion: We identified two highly specific algorithms that best ascertain patients hospitalized with influenza or RSV. These algorithms may be applied to hospitalized patients if data on laboratory tests are not available, and will thereby improve the power of future epidemiologic studies of influenza, RSV, and potentially other severe acute respiratory infections.
Employing Media Messaging Strategies to Respond to COVID-19 Misinformation
Authors: Field Rachel , Saeed Gul , Villada Rivera Mariana , Campanella Sabrina , Tailor Lauren 
Published: November 2021

Introduction: The COVID-19 pandemic has revealed critical gaps in the public’s knowledge of infectious diseases. Experts, including the World Health Organization, acknowledge that an “infodemic” of misinformation is spreading at the same time as the pandemic. Furthermore, 13% of Canadians age 50 and younger reported using social media as their primary source of information about COVID-19. Thus, in January 2020, the Infectious Disease Working Group (IDWG) was formed by a group of students at the Dalla Lana School of Public Health, University of Toronto. The IDWG’s Media Messaging Team (MMT) uses Knowledge Translation (KT) strategies to increase access to evidence-based information related to public health and COVID-19. Specifically, MMT uses virtual platforms, including Twitter and Instagram (@infectious_info), to disseminate information to a wide audience.
Objectives: The MMT aims to produce content to dispel pervasive and harmful myths about COVID-19, raise public awareness, and advocate for health equity.
Methods: The team creates 2-4 pieces of original content per week on topics such as Ontario Government legislation updates, myth-busting series, and “Wednesday Series” (summaries of novel research findings). The IDWG employs an equity lens to ensure that the content takes into account the experiences and needs of diverse groups, and that graphics are representative of a diverse audience. Health communication strategies are used to promote audience engagement through compelling and bold content design.
Results: The Instagram account has over 4,400 followers, with some posts surpassing 50,000 views. Qualitative feedback from social media followers indicates that this project is addressing an emerging gap in knowledge resulting from unclear messaging from official bodies, the spread of mis/disinformation, and disparities in health literacy levels.
Conclusions: The findings can inform the development and implementation of KT strategies to reach a wide audience and increase the uptake of public health information.
The Effect of Back Pain on Health Care Utilization and Costs
Authors: Wong Jessica J , Côté Pierre , Tricco Andrea C , Watson Tristan , Rosella Laura C 
Published: November 2021

Introduction: We assessed the effect of self-reported back pain on health care utilization and costs in a population-based sample of Ontario adults.
Methods: We conducted a population-based matched cohort study of Ontarian respondents aged ≥18 years of Canadian Community Health Survey (CCHS) from 2003-2012. CCHS data were individually linked to health administrative data to measure health care utilization and costs up to 2018. We propensity-score matched (hard-matched on sex) adults with self-reported back pain to those without back pain, accounting for sociodemographic, health-related, and behavioural factors. We evaluated back pain-specific and all-cause health care utilization and costs from healthcare payer perspective adjusted to 2018 Canadian dollars. Poisson and linear (log-transformed) models were used to assess healthcare utilization rates and costs.
Results: After propensity-score matching, we identified 36,806 pairs (21,054 for women, 15,752 for men) of CCHS respondents with and without back pain (mean age 51 years; SD=18). Compared to propensity-score matched adults without back pain, adults with back pain had two times the rate of back pain-specific visits (women: rate ratio [RR] 2.06, 95% CI 1.88-2.25; men: RR 2.32, 95% CI 2.04-2.64), 1.1 times the rate of all-cause physician visits (women: RR 1.12, 95% CI 1.09-1.16; men: RR 1.10, 95% CI 1.05-1.14), and 1.2 times the costs (women: 1.21, 95% CI 1.16-1.27; men: 1.16, 95% CI 1.09-1.23). Incremental annual per-person costs were higher in adults with back pain versus those without (women: $395, 95% CI $281-$509; men: $196, 95% CI $94-$300), corresponding to $532 million for women and $227 million CAD for men annually in Ontario.
Conclusions: Adults with back pain had considerably higher health care utilization and costs compared to adults without back pain. These findings provide the most recent, comprehensive, and high-quality estimates of the health system burden of back pain to inform healthcare policy and decision-making. New strategies to reduce the substantial burden of back pain are warranted.
Creencias de las mujeres víctimas de violencia que pertenecen a un estrato social alto en la Provincia de Tungurahua, Ecuador
Authors: Argotti Pilataxi Shirley Katherine , Jaramillo Zambrano Ana Elizabeth 
Published: November 2021

Introducción. La violencia contra la mujer ha sido un fenómeno social latente en Ecuador, existe una prevalencia de un 64.9% de violencia emocional, física, psicológica y negligencia hacia la mujer a lo largo de su vida. Las mujeres víctimas de maltrato de la clase socioeconómico alta no figuran en estudios sociales, psicológicos o jurídicos, debido a que no ponen denuncias, dificultando que los investigadores centren su atención en estudiar esta problemática. Por esta razón, surge la necesidad de investigar cuáles son las creencias que mantienen estas mujeres víctimas de violencia y así contribuir al estado del arte. Objetivo. identificar las creencias personales, familiares y sociales acerca de la violencia de la cual son víctimas las mujeres de estrato socioeconómico alto de la provincia de Tungurahua. Metodología. Es una investigación de enfoque cualitativo, de tipo no experimental y con alcance descriptivo y exploratorio debido a que pretende buscar, especificar propiedades, características y rasgos importantes mediante entrevistas semiestructuradas para analizarlas y así́ identificar las creencias de esta población. Se contó con una muestra de 10 mujeres de entre 25 a 60 años. Resultados. Se obtuvo como resultados que las mujeres de estrato socioeconómico alto mantienen creencias basadas en diferentes categorías como: personales, familiares y sociales, sobre la situación de violencia de la cual fueron en algún momento víctimas y que dichas creencias, las siguen manteniendo en esa condición de vida. Conclusión. Se concluye que las mujeres víctimas de violencia que pertenecen a un estrato social alto, mantienen creencias personales, familiares y sociales.
Розвиток виробництва безпілотних роботизованих систем в Україні засобами міжнародного воєнно-економічного співробітництва
Authors: Tolok Polina 
Published: November 2021

У статті проаналізовано міжнародний досвід розробки та виробництва безпілотних роботизованих систем, як перспективний напрям розвитку озброєнь та військової техніки. Висвітлено нормативно-правові, організаційні та економічні чинники, які стримують їх розвиток в України. Визначено пріоритети розвитку безпілотних роботизованих систем, одним із яких є застосування для цього інструментів міжнародного воєнно-економічного співробітництва, під яким запропоновано вважати міцні і тривалі зв'язки кооперативного характеру, в основі яких лежать вироблені та узгоджені наперед наміри, що закріплені в довготривалих економічних угодах і договорах у сфері розроблення та виробництва БПЛА та БПНА між вітчизняними компаніями – розробниками безпілотних роботизованих систем та провідними закордонними компаніями США, Туреччини, інших держав – членів НАТО, Ізраїлю з питань реалізації спільних проектів у цій сфері. Запропоновано для активізації виробництва безпілотних роботизованих систем різного призначення застосувати державно-приватне партнерство у оборонно-промисловому секторі України, що надає можливість створення спільних підприємств у формі господарських організацій для реалізації інвестиційно-інноваційних, капіталомістких, довготривалих проектів, що є міжнародною практикою. Саме завдяки цьому виникає можливість розподіляти ризики проекту, залучати до нього значні інвестиції та просувати товари/послуги на ринки інших країн. Запропоновано заходи з розвитку державно-приватного партнерства у цій сфері, зокрема: впровадження економічних механізмів ефективної взаємодії наукових установ та виробничих комплексів різних форм власності, а також державно-приватного партнерства підприємств, які забезпечують розроблення, виготовлення і модернізацію безпілотної техніки. Зазначено пріоритет розвитку міжнародного воєнно-економічного співробітництва у сфері безпілотної техніки: посилення експортного потенціалу вітчизняного ОПК, що має здійснюватися шляхом: розроблення та прийняття нормативно-правових актів, спрямованих на забезпечення заходів міжнародного воєнно-економічного співробітництва і реалізацію офсетних угод під час закупівлі роботизованих платформ та робототехніки за імпортом; укладення міжурядових угод з міжнародного воєнно-економічного співробітництва, що передбачають взаємний захист інвестицій, технологій, конкретні заходи із спільного виробництва безпілотної техніки для потреб ринків третіх держав; створення сприятливих умов для реалізації міжнародних проектів у сфері озброєнь і військової техніки, зокрема, забезпечення умов для створення спільного виробництва зразків безпілотної техніки, які не виготовляються в Україні.
Processo educacional sobre Cuidados Farmacêuticos e Síndrome Metabólica para implantação de Serviços Clínicos Farmacêuticos na Atenção Primária à Saúde
Authors: Cruz Manuela  Martins , Cassaro Karla Oliveira dos Santos , Falsoni Raiana Maria Prucoli , Brasil Girlandia Alexandre , Lima Ewelyne Miranda de , Dendasck Carla Viana , Pereira Leonardo Régis Leira , Castro Mauro Silveira de , Andrade Tadeu Uggere 
Published: November 2021

O presente estudo teve como objetivo avaliar o conhecimento dos farmacêuticos sobre Síndrome Metabólica (SM) e Cuidados Farmacêuticos antes e após a participação em processo formativo para implantação de farmácia clínica em farmácias comunitárias e compreender a percepção dos farmacêuticos sobre o processo ensino-aprendizagem. Trata-se de um estudo observacional descritivo, com abordagem quali-quantitativa realizado com farmacêuticos atuantes na atenção primária à saúde, no período de junho a julho de 2019. Os dados demonstraram um aumento do nível de conhecimento dos farmacêuticos após o treinamento em farmácia clínica com ênfase em SM, seguindo as recomendações da Federação Internacional Farmacêutica (FIP). A pesquisa registrou também um aumento do número de farmacêuticos com desempenho considerado bom e muito bom, sendo o maior aumento relacionado aos conteúdos sobre Cuidados Farmacêuticos. Tais resultados foram associados à percepção positiva dos farmacêuticos quanto ao conhecimento adquirido sobre os temas estudados e, também, em relação aos momentos formativos. Na conclusiva, o estudo constatou que o processo educacional melhorou o conhecimento dos farmacêuticos acerca da SM e dos cuidados farmacêuticos, sendo compreendido por eles como essencial para o desenvolvimento de habilidades clínicas, além de relevante para a garantia contínua do conhecimento desses profissionais e de sua atuação clínica e que, ainda, tem o potencial para favorecer a implantação de serviços clínicos em farmácias comunitárias de um sistema público de saúde.
Abordagens da terapia nutricional em pacientes com COVID-19: uma revisão integrativa
Authors: Araújo Flaviane Dantas de , Soares Albenize de Azevêdo , Lira Jayara Mikarla de , Silva Roseane Morais da , Felinto Rayssa da Silva , Soares Brenda Kelly Pontes , Nunes Ana Caroline da Fonseca , Oliveira Mayara Gabriela Cândido de , Silva Lisandra Mikaely Barboza da , Tinôco Lorena dos Santos , Silva José Adailton da , Clemente Heleni Aires 
Published: November 2021

O objetivo desse estudo foi realizar um levantamento na literatura cientifica das possíveis terapias nutricionais abordadas em pacientes com covid-19. É uma revisão do tipo integrativa, no qual foi realizada as buscas nas bases de dados PubMed, Scopus e Web of Science, sendo incluídos apenas artigos científicos publicados nos anos de 2020 a 2021. Para chave de busca foram considerados os descritores: “Nutrition Therapy”; “Coronavirus Infections” e sinonímias em inglês, onde foram encontrados 1.152 estudos, dos quais 8 foram incluídos. Os artigos analisados apresentaram diferentes condutas nutricionais; como resultados observou-se o suporte nutricional precoce de progressão lenta como alternativa eficiente, assim como, a terapia da nutrição enteral com início nas primeiras 24h ou 48h de admissão na UTI. Nada obstante, o risco nutricional é um fator relevante nestes pacientes, no qual a desnutrição se faz presente na maioria dos casos, todavia, manter o estado nutricional adequado é uma prioridade para sobrevivência dos mesmos. Desta forma, o manejo nutricional adequado é fundamental para pacientes infectados por covid-19, no qual um suporte adequado com nutrição enteral e a suplementação com o ômega-3 são favoráveis à recuperação e sobrevida desses pacientes, no entanto, são necessários mais estudos para esta última afirmação.
PEMBERDAYAAN MASYARAKAT MELALUI PELATIHAN PEMBUATAN TANAMAN HIDROPONIK SEBAGAI UPAYA MEREALISASIKAN KAMPUNG HIJAU DI KELURAHAN KEBON PALA KOTA ADMINISTRASI JAKARTA TIMUR
Authors: Erwin Bambang , Ismanto Riyadi , Panggalo Rein Vikaris , Nastiti Regina Tyas Awangsari 
Published: November 2021

Green Action merupakan kegiatan Pengabdian pada Masyarakat Program Studi Arsitektur Fakultas Teknik Universitas Kristen Indonesia (FTUKI) yang melibatkan dosen, mahasiswa dan masyarakat. Kegiatan Green Action 22 yang diwujudkan dalam bentuk wujud nyata Pengabdian pada Masyarakat pada semester Gasal tahun akademik 2020/2021 mengambil tema tentang tanaman hidroponik yang dikemas dalam 2 kegiatan yaitu kegiatan Pelatihan membuat tanaman hidroponik dan dilanjutkan dengan kegiatan lomba. Dalam laporan kegiatan Pengabdian pada Masyarakat berisi tentang kegiatan Pelatihan membuat tanaman hidroponik sebagai strategi mewujudkan kampung hijau di RW 09 Kelurahan Kebon Pala Jakarta Timur. Pemilihan usaha tanaman hidroponik sangat tepat dilakukan oleh masyarakat perkotaan (kampung kota) yang banyak tinggal di lahan yang tidak luas, terbatas, namun dapat direncanakan kondisi yang ada untuk membuat tanaman hidroponik dan dapat dimanfaatkan minimal untuk kebutuhan keluarga. Keterbatasan lahan, kepadatan penduduk, kondisi tertentu misalnya masa pensiun, masa pandemic covid 19 seperti sekarang ini, membuat tanaman hidroponik merupakan pilihan yang paling tepat. Dengan waktu luang di rumah lebih banyak karena Work From Home (WFH) dapat mengisi waktu dengan berkegiatan menanam hidroponik, sebagai hiburan, menghilangkan stress, dan menghasilkan uang. Metode yang dilakukan adalah mengadakan Pelatihan Pembuatan Tanaman Hidroponik dengan narasumber pakar Hidroponik, yang diikuti oleh 5 RT di RW 9 sebagai peserta. Hasil rapat koordinasi dengan aparat pemerintahan tingkat kelurahan dan RW, wakil RT setempat, ditentukan hanya 5 RT masing-masing RT diwakili 1-2 peserta. Metoda pelatihan mengingat harus menjaga Protokol Kesehatan secara ketat, semua kegiatan dilaksanakan secara online/daring.
Kata Kunci : Green Action, Pelatihan Hidroponik, Kampung Hijau
Troilus and Cressida's Folio Prologue in the Poets’ War: Shakespeare, Jonson, Marston
Authors: Held Joshua R. 
Published: November 2021

Although many scholars have denigrated Troilus and Cressida, the Folio version of the play—with a prologue—offers a more tractable, even winsome play than does the quarto version. As a buffer between the real world of an audience and the imagined world of a play, the prologue adjusts the expectations of an audience, highlighting at once its own potency and the interpretive potential of this textual difference between quarto and Folio. This Prologue conveys an appeal neither obsequious nor arrogant—as do its respective models in John Marston's Antonio and Mellida and Ben Jonson's Poetaster—but rhetorically sinuous and eminently tactful, at once calming the war of the theaters and previewing the subtle tonal shifts in the play that follows it. In Poetaster, Jonson presents “An armed Prologue,” which has often been mentioned as a precursor to Shakespeare's Troilus Prologue, but I argue that its surface similarities only highlight its differences in goals, methods, and most importantly tone. And by contrast with the epilogue in Antonio and Mellida, the Troilus Prologue presents a more subtly nuanced attempt to win the favor of an audience not wholly by self-effacement but by complex honesty and mimetic rhetoric, counterbalanced to anticipate the perplexing world of Shakespeare's play.
Biomarkers of Gut Microbiota in Chronic Spontaneous Urticaria and Symptomatic Dermographism
Authors: Liu Runqiu , Peng Cong , Jing Danrong , Xiao Yangjian , Zhu Wu , Zhao Shuang , Zhang Jianglin , Chen Xiang , Li Jie 
Published: November 2021

BackgroundChronic urticaria (CU) is a chronic inflammatory skin disease associated with Th2 immune response. The two most common subtypes of CU, i.e., chronic spontaneous urticaria and symptomatic dermographism (CSD), often coexist. However, the pathogenesis of CSD is still unclear. Gut microbiota plays an important role in immune-related inflammatory diseases. The purpose of this study was to explore the correlation between gut microbiota and CSD.MethodsA case-control study was conducted on CSD patients as well as gender- and age-matched normal controls (NCs). The 16S ribosomal DNA sequencing of fecal samples was used to detect the gut microbiota of all subjects. QPCR was used to further verify the species with differences between the two groups.ResultsThe alpha diversity of gut microbiota decreased in CSD patients, accompanied by significant changes of the structure of gut microbiota. Subdoligranulum and Ruminococcus bromii decreased significantly in CSD patients and had a potential diagnostic value for CSD according to receiver operating characteristic curve (ROC) analysis. Enterobacteriaceae and Klebsiella were found to be positively correlated with the duration of CSD, while Clostridium disporicum was positively correlated with the dermatology life quality index (DLQI).ConclusionsThe gut microbiota of CSD patients is imbalanced. Subdoligranulum and Ruminococcus bromii are the gut microbiota biomarkers in CSD.
Applicability of On-Site P-Wave Earthquake Early Warning to Seismic Data Observed During the 2011 Off the Pacific Coast of Tohoku Earthquake, Japan
Authors: Tsuno Seiji 
Published: November 2021

In this study, the on-site P-wave earthquake early warning (EEW) based on the site-specific spectral ratio of S-wave to P-wave to efficiently incorporate the site characteristics, which can potentially issue the earthquake warning by the time of Ts-p, was developed. The spectral ratio of S-wave to P-wave that are related to the source effects, the path effects, and the site effects are significantly affected by the site effects contrast to the source effects and the path effects in practical. At first, the on-site P-wave EEW method which multiplies a site-specific spectral ratio of S-wave to P-wave prepared in advance by P-wave observed in the real-time at seismic stations is applied to seismic data for moderate-sized earthquakes with a magnitude (Mj) of 5.0–6.0, occurred in the eastern Japan, observed at both the sedimentary basin site and the rock site. As a result, this method predicted well the observed S-wave in the single indicator of SI within the logarithmic standard deviation of 0.25 as well as in the frequency of more than 0.5 Hz. It is, also, confirmed that the site-specific spectral ratio of S-wave to P-wave at a seismic station was stably retrieved from 20 data samples at least. To investigate the applicability of this method to earthquake ground motions induced by a large-scaled earthquake, finally, this method is applied to seismic data during the 2011 off the Pacific coast of Tohoku earthquake, Japan (Mw 9.0). The prediction of S-wave using a time-window of 10 s after P-wave arrived, could not reproduce the observation with the underestimation; however, the prediction of S-wave using a time-window of more than 20 s containing P-wave propagated from an area generating strong motions in the fault, could reproduce the observation. Even in the case of the large-scaled earthquake, the on-site P-wave EEW method based on the site-specific spectral ratio of S-wave to P-wave at a seismic station availably works by using the gradually increasing time-windows after P-wave arrived in the single indicator of SI as well as in the frequency content, avoiding the mixture of S-wave into a part of P-wave.