bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vitryssland eller Belarus?: Namnskick, långdistansnationalism och identitetspolitik
Authors: Rudling Per Anders 
Published: December 2021

In 2019, the Swedish government officially switched terminology from using the traditional endogenous term Vitryssland to the exogenous Belarus. Vitryssland (lit: White Russia) had been in use in the Swedish language since the 17th century, and the decision was neither easy nor swift. There was no consensus about the utility of the change, and significant opposition from linguists and editors against abandoning a term which had emerged and become established over centuries of contact. The debate preceding the switch was often shrill, led by activists and steeped in identity politics. In fact, controversies regarding what to call the country were nothing new, highlighting diverging visions of its geopolitical and cultural position between East and West. Discussions mirrored the far more emotional and polarized discussions among Belarusian nationalists in the 20th century, which at times became violent. Kryvia, Byelorussia, Greatlitva were but some of contenders. This article is an attempt to place discussions about the Swedish terminology in the larger context of history, memory, geopolitics and identity politics.
Influence of the dual COX-2/5-LOG inhibitor on the activity of L-arhinin/NO system in rat's blood with experimental ulcer of the stomach
Authors: O. P. Khavrona  
Published: December 2021

A large spread of stomach ulcer causes the search for new effective gastroprotective drugs, which would possess antioxidant properties. It is established that the disease is accompanied by the imbalance in the system L-arhinin/NO. This is manifested by the activation of the NO-synthase pathway of L-arginine and is accompanied by excessive formation of nitric oxide. It is proved that the use of dual inhibitor COX-2/5-LOG normalizes deviation in the L-arhinin/NO system. This shows antioxidant and cytoprotective properties of the substance.
Writing a degree work as a key method of specialists training optimization in the specialty "Pharmacy"
Authors: I. P. Kutynska  
Published: December 2021

One of the key methods of specialist training optimization in the specialty "Pharmacy" is writing and defense of degree works. This kind of research plays an important role in forming the creative potential of students, aimed to developing analytical and creative abilities, intelligence, memory, improving the learning of educational material in accordance with state educational standards.
Status of lipid peroxidation and antioxidant defence system in drug-induced liver damage in patients with chronic lymphocytic leukemia
Authors: T. I. Grydzhuk  
Published: December 2021

The paper analyzes the impact of chemotherapy in patients with chronic lymphocytic leukemia in the functional state of the liver.The formation of differentiated types of drug- induced liver damage, depending on the characteristics of cytostatic therapy has been established. The intensity of lipid peroxidation and antioxidant defence stress in patients with drug- induced liver damage on a background of chemotherapy and the presence of correlation relationships between the intensity of cytolysis and severity of lipid peroxidation have been proved.
Differentiation of fatty tissue stromal cells under different conditions of experimental cell transplantation
Authors: D. B. Dombrovskyi  
Published: December 2021

Fatty tissue has been lately considered by researchers as an accessible source of autological stem cells. The problem of factors which influence the directed differentiation of stem cells is still important. Experimental researches have been conducted on rats with simulated limb ischemia. Stromal-vascular fraction of fatty tissue was injected to the experimental animals both with limb ischemia and to those with intact extremities. Imunohistochemical researches (determination of antibodies expression to von Willebrand factor, of collagen IV type and vimentin) of processes, which take place with introduced multipotential stromal cells, the number of which is great in stromal-vascular fraction of fatty tissue against the background of ischemia and without it, have been conducted. These results allow defining the future subsequent development of this direction of researches.
Early and delayed reaction of temporal lobe cells of rats’ cerebral hemisphere to ischemia-reperfusion lesion
Authors: Т. I. Kmet  
Published: December 2021

It has been established that brain cell density is significantly reduced in the temporal lobe after a 20-minute carotid ischemia and one-hour reperfusion. Density and fraction of carotid cells of the temporal lobe with signs of apoptosis increase significantly on the 12th day of the study, due to reducing the number of neurons and especially glial cells. Ischemia-reperfusion lesion of the cerebral cortex in the investigated lobe leads to the most expressed disorders of neuron’s morphometric parameters both in the early and late period of ischemia-reperfusion.
Optimization of the reparative osteogenesis in case of atypical teeth extraction
Authors: N. B. Kuzniak  , M. P. Prodan  , S. I. Tryfanenko  
Published: December 2021

The platelet-rich plasma (PRP) is a natural material which actively helps to stimulate the repair process. The evidence based spectrum for using the PRP is wide and deals with many branches of medicine. In stomatology this method is mostly used in combination with osteoplastic materials in case of the sinus lift surgery, augmentation of the alveolar crest, periodontal and implanting intervention. In this research we used PRP for optimization of the reparative osteogenesis after an atypical tooth extraction.
Nonspecific body reactivity in patients with diabetes mellitus depending on its type
Authors: O. A. Olenovych  
Published: December 2021

According to the results of complex assessment of integral haematological coefficients the development of endogenous intoxication was revealed in case of diabetes mellitus, whose intensity depends on the type of the disease and causes immune system disorganization. The decrease of functional activity of specific immunity as well as nonspecific one in case of diabetes mellitus leads to deregulation of cellular and humoral reactions and depends on diabetes type: in diabetes type 1 the reduction of nonspecific immunoresistance is contributed by microphages, in diabetes type 2 – by macrophages, accompanied by the deficiency of specific immune defense, reliably more significant in diabetes type 2.
The system of nitrogen oxide generation of small intestine in experimental gastroenterocolitis
Authors: A. S. Tkachenko  , V. H. Hopkalov  , M. A. Orlova  
Published: December 2021

The activity of endothelial and inducible NO-synthases and the content of S-nitrosothiols were studied in the small intestine homogenates of rats with chronic experimental gastroenterocolitis caused by food additive carrageenan intake during 2 and 4 weeks. It was established that carrageenan intake during 2 weeks led to a decrease of eNOS activity and increased the activity of iNOS in small intestine homogenate, causing increased production of NO and, therefore of Snitrosothiols. A decreased NO synthesis in four-week use of carrageenan indicated a potential role of NO deficiency in the development of microcirculatory disorders and chronic inflammation.
History of formation of thephthisiology and pulmonology department of Bukovinian state medical university, prospect of advance
Authors: L. D. Todoriko  , A. V. Boiko  , V. P. Shapovalov  , V. O. Stepanenko  , V. I. Slyvka  , I. O. Semianiv  , A. M. Ahmed  
Published: December 2021

The directions of scientific, methodical and clinical activity of the Phthisiology and Pulmonology department staff at each stage of its formation as well as the prospects of its development have been covered in this article. The relevance of further researches concerning the effectiveness of modern chemotherapy program and creation of new vaccines and medications to optimize treatment of patients with drug resistant TB was grounded.
Changes in endothelial system condition in patients with bronchial asthma after using the preparation L-arginin in a complex therapy
Authors: S. A. Bazarova  
Published: December 2021

Research objective was to study influence of L-arginin on endothelial system indexes in patients with bronchial asthma. 82 patients with bronchial asthma have been examined. 2 groups have been formed. Patients of the basic group in addition to standard basic therapy received the nitrogen oxide donator - L-arginin. The comparison group only received a basic therapy. The condition of endothelial system was estimated before and after ten-day course of treatment based on the following indicators: changes in the level of the main stable metabolites of nitrogen oxide in plasma of blood and in a condensate of exhaled air as well as that of L-arginin in plasma.
Study of autoimmune thyroiditis and coeliac disease prevalence in patients with juvenile rheumatoid arthritis
Authors: Ya. Ye. Boiko  , I. I. Hrytsiuk  
Published: December 2021

The aim of this investigation was to study prevalence of autoimmune thyroiditis and celiac disease in 39 patients with JRA. Autoimmune euthyroid thyroiditis was diagnosed in 8 % of patients with JRA. Antithyroid antibodies were found in JRA female patients with oligoarticular form of the disease and with predominant presence of antinuclear antibodies. Screening for presence of tissue transglutaminaze antibodies did not reveal celiac disease in patients with JRA.
Cord blood derived nuclear cells usage in animal model of neovascular retinopathy
Authors: Dyomin Y. A. , Biletska P. V. 
Published: December 2021

The effect of cord blood derived nuclear cells on neovascular retinopathy in experimental rats was studied. Regression of neovascular tissue, retinal structure normalization was found after 45 day post single intravitreal injection of cord blood derived nuclear cells.
Activity of the liver enzymes in children’s serum in case of chronic and exacerbative granulating apical periodontitis in permanent teeth
Authors: I. R. Kostiuk  
Published: December 2021

The study involved 63 children with granulating periodontitis of permanent teeth, aged 12-1 and determined the activity of liver enzymes: arginase, cholinesterase, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) of serum. A marked increased activity of arginase and decrease in cholinesterase activity in case of chronic granulating apical periodontitis of permanent teeth and in case of the exacerbation of this pathological process have been revealed. It was also found a significant increase of ALT and AST parameters in case of the exacerbation of disease. The results obtained suggest that periodontal pathology affects the functional activity of the liver cells.
Pharmacological correction of morphological changes in the esophageal mucosa and of apoptosis markers in patients with gastroesophageal reflux disease combined with diabetes mellitus type 2
Authors: Yu. V. Kohaniuk  , O. I. Fediv  , I. S. Davydenko  
Published: December 2021

This article is devoted to comparison of the nature of morphological changes in the esophageal mucosa and of apoptosis markers in patients with gastroesophageal reflux disease combined with diabetes mellitus type 2. The possibility to eliminate a disbalance in apoptosis regulators in the blood and improvement of some parameters of the morphological status of the esophageal mucosa of patients with gastroesophageal reflux disease combined with diabetes mellitus type 2, by including pepsan and quercetin to the complex treatment schemes has been established.
A hereditary component in development of immune disturbances in children with chronic sinusitis
Authors: S. А. Levytska  
Published: December 2021

The immune disturbances in exudative and hyperplastic forms of chronic sinusitis are accompanied by depression of cell immune response and activation of the humoral one; by a deficit of the factors and mechanisms of nonspecific resistance of organism. A hypothesis of genetic conditionality of the peculiarities of immune reactions and development of the type of chronic inflammation in paranasal sinuses was put forward. The cytosine in position 511 of the promoter zone of ІL-1β-gene aggravates the suppression of the cell-link of immunity response and a deficit of factors of nonspecific resistance in case of chronic exudative sinusitis while thymine in position 590 of promoter zone of ІL-4-zone increases the deficit of factors of non-specific resistance in case of chronic polypous inflammation of paranasal sinuses.
Factors of arterial mediacalcification progression in diabetic foot syndrome
Authors: I. Ya. Mykhaloiko  
Published: December 2021

The study involved 75 patients with SDF with diabetes type II, a severe form of subcompensated course. Among them – 62 men and 13 women. 63 patients had a mixed form of SDF, including 50 patients with varying degrees of severity media calcification (MC) arteries, 13 patients without media calcification arteries, 12 patients with diagnosed neuropathic form of SDF. The most pronounced distal polyneuropathy was diagnosed in patients with degrees III -V of MC. Results in this group were significantly higher compared with groups without MC, with I-II degree of its severity and neuropathic form of SDF (p<0,05). Also, we have observed that the longest duration of disease and age of the patients was the oldest in the group of III - V MС degree. In this group of patients, we found significantly higher levels of fasting glucose, compared with other groups (p<0,05). So, one of the pathogenetic links of media calcification can be expressed distal diabetic neuropathy, which causes the distal type of arterial disease. Progression of media calcification associated with ageing, disease duration of diabetes and elevated levels of glucose in the blood. Early detection and treatment of diabetic polyneuropathy may serve as a measure of prevention of media arterial calcification.
Malabsorption syndrome as a manifestation of systemic effects in advanced forms of pulmonary tuberculosis
Authors: Todoriko L. D. , Yeremenchuk I. V. , Shapovalov V. P. , Ilchyshyn T. I. 
Published: December 2021

As of October 2012 84 countries had reported at least 1 case of extensively drug resistant tuberculosis (EDR TB). In November 2012, the WHO epidemiological surveillance stated: all new TB cases in the world are 3,7 % of multi-drug resistant tuberculosis (MDR TB); 60,0 % of MDR TB among the new cases of TB are documented in Brazil, China, India, and South Africa.
Somatotype role in the identification of phenotypic human features
Authors: S. M. Fedorchuk  , E. P. Fedorchuk-Neznakomtseva  
Published: December 2021

As a result of one-and multivariate statistical analysis of anthropometric and osteometric parameters, linear regression equation for determining the differentiation of the somatotype and determination of the anthropometric parameters of the person have been developed.
Current issues of shin arteries reconstructive surgery (review of the references)
Authors: Y. M. Dybiak  
Published: December 2021

WHO estimates that from 5 to 15 % of the population suffer from chronic obliterating diseases of lower limbs arteries. At the same time, occlusion-stenotic lesions of the distal channel are observed in about 43 % of these patients, indicating the extraordinary prevalence of the problem. This situation requires further search for ways to improve the treatment of patients with distal occlusion. Thereto, we analyzed the published data, which allowed to select, and, to some extent, organize practical problems, vascular surgeons face while performing distal reconstructions. These included: - the choice of the optimal method of reconstruction; choice of the tibial artery for distal anastomosis; small size of the tibial arteries, making it difficult to impose anastomosis; the difference between the diameters of reversive veins and of tibial arteries; fibrous transformation of the distant vein due to the destruction of vasa vasorum; loose type of great saphenous vein or its obliteration. Summing up our analysis of published data, we conclude that the questions of shin shunting are far from being resolved, and require an integrated approach, taking into account the anatomical and morphological features of the distal channel, type of transplant material, and expertise of the clinic.
Contemporary methods of surgical stress functional diagnostics (literature review and own data)
Authors: О. J. Мokryk  , V. M. Horytskyi  
Published: December 2021

New data about functional methods of diagnostics used for detection of acute stress physiological manifestation in patients during surgery and dental interventions is presented in the review. Modern scientific and technical developments that have been implemented in medicine helping professionals estimate psycho-emotional state of each patient objectively, determine nervous, cardiovascular and respiratory systems reactivity during postsurgical stress and monitor the efficiency of premedicative preparation and anesthesia methods used are considered. The results of own investigation are represented.
A new sight on the biomechanics of fractures of the lower extremity long tubular bones
Authors: Savka Ivan , Malyshev Valentyn , Savka Svitlana 
Published: December 2021

The main objective of our work is to study of the modern aspects of the biomechanics of fractures of the lower extremity long tubular bones in cases of mechanical trauma. The objects of our studies were 576 samples and 128 expert cases with injuries of the femoral bones, tibia and fibula. The data obtained were statistically processed with the use of multi-factor dispersion analysis. Three grouped hierarchical biomechanical modules have been found to be the most reasonable to apply in detection of mechanical and morphogenesis of fractures of low extremity long tubular bones: elasticity, stiffness and solidity including the most valuable diagnostic morphological signs grouped by the degree of their influence on destructive processes of the given bones.
Objective: to study of the modern aspects of the biomechanics of fractures of the lower extremity long tubular bones in cases of mechanical trauma for objective retrospective establishment of the mechanisms of fracture formation.
Materials and methods. The material of our study included 576 samples of the femoral bone, tibia and fibula, taken from 16 male and female biomannequins aged from 24 to 70 without their traumatic injuries, visual pathological changes or some mentions about them in the anamnesis. Expert examinations involved also 82 individuals with 128 injures of the lower extremities: femurs – 40 cases, tibia – 46 cases, fibula – 42 cases. The data obtained were statistically processed with the use of multi-factor dispersion analysis.
Conclusions:

Various portions of long tubular bones of the lower extremity have a number of structural-functional It is presented in macro- and micro-architecture of the bone and influences upon the resistance to external mechanical forces and morphological characteristics of fractures of these bones.
Three grouped hierarchical biomechanical modules have been found to be the most reasonable to apply in detection of mechanical and morphogenesis of fractures of low extremity long tubular bones: elasticity, stiffness and solidity including the most valuable diagnostic morphological signs grouped by the degree of their influence on destructive processes of the given

Prospects of further studies. The prospects of future studies consists of further comprehensive examination of interrelations between the main structural components of the osseous tissue and regularities of formation of morphological signs in case of fractures of various bones of the human skeleton.
Dynamics of microscopic changes of the achilles tendon for two weeks after the death
Authors: Povstianyi Vitalii 
Published: December 2021

This article discusses the question of determining the time of death. To date, there is no common method of establishing prescription of death, especially after 2-3 days after the onset of death.
Aim research. Evaluation of changes that occur in the tissue of the Achilles tendon at various time of post-mortem period. Materials and Methods. The histological microscopic sections of the Achilles tendon were investigated. The material was collected from the people corpses at the age of 45-65 years, with the death prescription from 5 hours to 11 days.The peculiarities of microscopic picture in the connective tissue have been ascertained on different stages after death on the basis of the histological preparations’ investigation. These changes were characterized by the increasing of processes destruction of intercellular matrix and by cells’ edema until their complete decay.
Conclusions 1. In the post-mortem period process of autolysis in the tissue of the Achilles tendon develops slowly.

The gradual destruction of the connective tissue cells, allow using this phenomenon for determining the time of death.
The Design and Development of the i-Jury Management System
Authors: Mohamad Rosman Mohamad Rahimi , Abdullah Nurulannisa , Arshad Izzatil Husna , Md. Saleh Mohamad Sayuti , Mohd Zawawi Mohd Zafian , Fadzil Faizal Haini 
Published: December 2021

Handling an event requires a repetitive and complex task; from initial preparation until its conclusion. One of the important elements in an innovation event is the jurying process. The jurying process usually involves tasks with higher priority and must be completed in limited duration, usually within 4 to 5 days. The inexistence of inexpensive jurying information systems leads to the development of the i-Jury management system (i-Jury). The i-jury management system was developed based on PHP programming language, MySQL database, and jQuery. The development of the information system follows the System Development Lifecycle methodology. The findings show that the development of the information system speeds up the process of managing jury, project management, as well as speeding up the disbursement of results, comparing to previous traditional evaluation methods
Effectiveness Of Quizizz in Interactive Teaching and Learning Malay Grammar
Authors: Munuyandi Thulasirani A/P , Husain Salina , Abdul Jabar Mohd Azidan , Jusoh Zuraini 
Published: December 2021

Abstract: For teaching and learning Malay language grammar, there are many types of online assessment tools and applications have been developed in Malaysia. One such application is Quizizz, a game-based online quiz that facilitates teaching and learning. The purpose of this research is to measure the effectiveness of Quizizz application to teach and learn Malay grammar. We have used descriptive questionnaire research design, and chosen 130 students from Tamil schools by following the simple random sampling strategy. We have explored the effectiveness of Quizizz application as a formative quizzing tool for teaching and learning Malay grammar in year-four Tamil school students from 15 Tamil schools in Manjung district. The results showed that it was imperative to use Quizizz as a formative assessment tool to learn and teach Malay grammar to Tamil students. Students also responded positively to the use of Quizizz in the classroom through survey questionnaire results. At the end, we conclude that it is important for teachers to consider using fun and entertainment technology quizzing tools to teach Malay grammar.

Keywords: Malay grammar, Quizizz, Self-assessment, Teaching and learning