bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implications on Feature Detection When Using the Benefit–Cost Ratio
Authors: Jagdhuber Rudolf , Rahnenführer Jörg 
Published: June 2021

AbstractIn many practical machine learning applications, there are two objectives: one is to maximize predictive accuracy and the other is to minimize costs of the resulting model. These costs of individual features may be financial costs, but can also refer to other aspects, for example, evaluation time. Feature selection addresses both objectives, as it reduces the number of features and can improve the generalization ability of the model. If costs differ between features, the feature selection needs to trade-off the individual benefit and cost of each feature. A popular trade-off choice is the ratio of both, the benefit–cost ratio (BCR). In this paper, we analyze implications of using this measure with special focus to the ability to distinguish relevant features from noise. We perform simulation studies for different cost and data settings and obtain detection rates of relevant features and empirical distributions of the trade-off ratio. Our simulation studies exposed a clear impact of the cost setting on the detection rate. In situations with large cost differences and small effect sizes, the BCR missed relevant features and preferred cheap noise features. We conclude that a trade-off between predictive performance and costs without a controlling hyperparameter can easily overemphasize very cheap noise features. While the simple benefit–cost ratio offers an easy solution to incorporate costs, it is important to be aware of its risks. Avoiding costs close to 0, rescaling large cost differences, or using a hyperparameter trade-off are ways to counteract the adverse effects exposed in this paper.
Validation of the French-Canadian Version of the Sexual Inhibition and Sexual Excitation Scales-Short Form (SIS/SES-SF): Associations With Sexual Functioning, Sociosexual Orientation, and Sexual Compulsivity
Authors: Nolet Kévin , Guay Jean-Pierre , Bergeron Sophie 
Published: June 2021

Abstract

Introduction
The Dual control model proposes that both excitatory and inhibitory processes are responsible for the human sexual response.

Aim
To validate the French-Canadian translation of the Sexual Inhibition and Excitation Scales-Short Form (SIS/SES-SF) by exploring its factor structure and by investigating its capacity to retrospectively predict sexual functioning and behaviors, namely, sociosexual orientation and sexual compulsivity.

Methods
A French-Canadian translation of the SIS/SES-SF was created using forward-backward translation. A community sample of 362 men and 420 women completed an online survey. The factor structure and the measurement invariance between men and women was explored using Exploratory Structural Equation Modeling. Predictive power of the scales was tested using Multiple Linear Regression models using a corrected threshold (P&lt; .008).

Main outcome measures
Sexual functioning was assessed using the International Index of Erectile Function and the Female Sexual Function Index while sexual compulsion and sociosexual orientation were measured using the Sexual Compulsion Scale and the Revised Sociosexual Orientation Inventory, respectively.

Results
The original three-factor solution of the SIS/SES-SF was replicated. All three scales showed acceptable internal consistency and good temporal stability. Yet, results only supported configural measurement invariance between men and women, suggesting that their scores cannot be directly compared. Overall, for both men and women, higher sexual excitation (SES) was significantly predictive of better sexual functioning, while higher sexual inhibition due to threat of performance failure (SIS1) was a significant predictor of lower sexual functioning. Both sexual compulsivity and sociosexual orientation were significantly predicted by higher SES and lower sexual inhibition due to threat of performance consequences (SIS2).

Conclusion
These results support the cross-cultural transferability of the SIS/SIS-SF and the Dual control model to French-Canadian men and women, higlighting the utility for clinicians to evaluate both excitatory and inhibitory factors associated with sexual dysfunction and sexual behaviors. Nolet K, Guay JP, Bergeron S. Validation of the French-Canadian Version of the Sexual Inhibition and Sexual Excitation Scales-Short Form (SIS/SES-SF): Associations With Sexual Functioning, Sociosexual Orientation, and Sexual Compulsivity. Sex Med 2021;9:100374.
Small World
Authors: Deane Seamus , Cleary Joe 
Published: June 2021

Seamus Deane is one of the most vital and versatile authors of our time. His new book presents an unmatched survey of Irish writing, and of writing about Irish issues, from 1798 to the present day. Elegant, polemical and trenchant, it addresses the political, aesthetic and cultural dimensions of several notable literary and historical moments, and monuments, from the island's past and present. The style of Swift; the continuing influence of Edmund Burke's political thought in the USA; the echoing debates about national character; aspects of Joyce's and of Elizabeth Bowen's relation to modernism; memories of Seamus Heaney; analysis of the representation of Northern Ireland in Anna Burns's fiction – these topics constitute only a partial list of the themes addressed by a volume that should be mandatory reading for all those who care about Ireland and its history. The writings included here, from one of Irish literature's most renowned critics, have individually had a piercing impact, but they are now collectively amplified by being gathered together here for the first time between one set of covers. Small World: Ireland, 1798–2018 is an indispensable collection from one of the most important voices in Irish literature and culture.
Riboflavin intake, MTRR genetic polymorphism (rs1532268) and gastric cancer risk in a Korean population: a case–control study
Authors: Lu Y-Thanh , Gunathilake Madhawa , Lee Jeonghee , Choi Il Ju , Kim Young-Il , Kim Jeongseon 
Published: June 2021

AbstractThe vitamin B group, including riboflavin, plays paramount roles in one-carbon metabolism (OCM), and disorders related to this pathway have been linked to cancer development. The variants of genes encoding OCM enzymes and the insufficiency of B vitamins could contribute to carcinogenesis. Very few observational studies have revealed a relationship between riboflavin and gastric cancer (GC), especially under conditions of modified genetic factors. We carried out a study examining the association of riboflavin intake and its interaction with MTRR (rs1532268) genetic variants with GC risk among 756 controls and 377 cases. The OR and 95 % CI were evaluated using unconditional logistic regression models. We observed protective effects of riboflavin intake against GC, particularly in the female subgroup (OR = 0·52, 95 % CI 0·28, 0·97, Ptrend = 0·031). In the MTRR (rs1532268) genotypes analysis, the dominant model showed that the effects of riboflavin differed between the CC and CT + TT genotypes. Compared with CC carriers, low riboflavin intake in T+ carriers was significantly associated with a 93 % higher GC risk (OR = 1·93, 95 % CI 1·09, 3·42, Pinteraction = 0·037). In general, higher riboflavin intake might help reduce the risk of GC in both CC and TC + TT carriers, particularly the T+ carriers, with marginal significance (OR = 0·54, 95 % CI 0·28, 1·02, Pinteraction = 0·037). Our study indicates a protective effect of riboflavin intake against GC. Those who carry at least one minor allele and have low riboflavin intake could modify this association to increase GC risk in the Korean population.
Nutrition Module design in Maintain Your Brain: an internet-based randomised controlled trial to prevent cognitive decline and dementia
Authors: Almendrales Rangel Carolina , Noble Yian , Radd-Vagenas Sue , Mavros Yorgi , Flood Victoria M. , O’Leary Fiona , Brodaty Henry , Sachdev Perminder S. , Heffernan Megan , Valenzuela Michael , Anstey Kaarin J. , Daniel Kenneth , Ginige Jeewani A. , San Jose Juan C. , Chau Tiffany , Garnés Rancurello Sandra , Fiatarone Singh Maria A. 
Published: June 2021

AbstractThe Maintain Your Brain (MYB) trial is one of the largest internet-delivered multidomain randomised controlled trial designed to target modifiable risk factors for dementia. It comprises four intervention modules: physical activity, nutrition, mental health and cognitive training. This paper explains the MYB Nutrition Module, which is a fully online intervention promoting the adoption of the ‘traditional’ Mediterranean Diet (MedDiet) pattern for those participants reporting dietary intake that does not indicate adherence to a Mediterranean-type cuisine or those who have chronic diseases/risk factors for dementia known to benefit from this type of diet. Participants who were eligible for the Nutrition Module were assigned to one of the three diet streams: Main, Malnutrition and Alcohol group, according to their medical history and adherence to the MedDiet at baseline. A short dietary questionnaire was administered weekly during the first 10 weeks and then monthly during the 3-year follow-up to monitor whether participants adopted or maintained the MedDiet pattern during the intervention. As the Nutrition Module is a fully online intervention, resources that promoted self-efficacy, self-management and process of change were important elements to be included in the module development. The Nutrition Module is unique in that it is able to individualise the dietary advice according to both the medical and dietary history of each participant; the results from this unique intervention will contribute substantively to the evidence that links the Mediterranean-type diet with cognitive function and the prevention of dementia and will increase our understanding of the benefits of a MedDiet in a Western country.
Childhood trauma is associated with reduced frontal gray matter volume: a large transdiagnostic structural MRI study
Authors: Begemann Marieke J. H. , Schutte Maya J. L. , van Dellen Edwin , Abramovic Lucija , Boks Marco P. , van Haren Neeltje E. M. , Mandl Rene C. W. , Vinkers Christiaan H. , Bohlken Marc M. , Sommer Iris E. C. 
Published: June 2021

AbstractBackgroundChildhood trauma increases risk for psychopathology and cognitive impairment. Prior research mainly focused on the hippocampus and amygdala in single diagnostic categories. However, other brain regions may be impacted by trauma as well, and effects may be independent of diagnosis. This cross-sectional study investigated cortical and subcortical gray matter volume in relation to childhood trauma severity.MethodsWe included 554 participants: 250 bipolar-I patients, 84 schizophrenia-spectrum patients and 220 healthy individuals without a psychiatric history. Participants filled in the Childhood Trauma Questionnaire. Anatomical T1 MRI scans were acquired at 3T, regional brain morphology was assessed using Freesurfer.ResultsIn the total sample, trauma-related gray matter reductions were found in the frontal lobe (β= −0.049,p= 0.008;q= 0.048), this effect was driven by the right medial orbitofrontal, paracentral, superior frontal regions and the left precentral region. No trauma-related volume reductions were observed in any other (sub)cortical lobes nor the hippocampus or amygdala, trauma-by-group (i.e. both patient groups and healthy subjects) interaction effects were absent. A categorical approach confirmed a pattern of more pronounced frontal gray matter reductions in individuals reporting multiple forms of trauma and across quartiles of cumulative trauma scores. Similar dose−response patterns were revealed within the bipolar and healthy subgroups, but did not reach significance in schizophrenia-spectrum patients.ConclusionsFindings show that childhood trauma is linked to frontal gray matter reductions, independent of psychiatric morbidity. Our results indicate that childhood trauma importantly contributes to the neurobiological changes commonly observed across psychiatric disorders. Frontal volume alterations may underpin affective and cognitive disturbances observed in trauma-exposed individuals.
“That Democratic Ink Must Be Wiped Away”: Hobbes and the Normativity of Democracy
Authors: Holman Christopher 
Published: June 2021

AbstractHobbes's preference for monarchical sovereign forms and his critique of democratic political organization are well known. In this article I suggest, however, that his opposition to democratic life constitutes the central frame through which we must understand some of the most important theoretical mutations that occur throughout the various stages of his civil science. Key alterations in the Hobbesian political theory from The Elements of Law to Leviathan can be interpreted as efforts to retroactively foreclose the emergence of a substantive democratic normativity that the prior theoretical framework allowed for or suggested. Hobbes's opposition to democracy is ultimately so significant so as to fundamentally structure various key elements of his political philosophy.
Horace's Programmatic Priamel
Authors: Sullivan Michael B. 
Published: June 2021

AbstractHorace's MAECENAS ATAVIS (Hor.,Carm.1.1) is shown to enumerate nine allusive icons whose attributes evoke signature elements in the works and biographical traditions of the nine canonical Greek lyric poets. In his first ode the Roman poet thus announces the commencement of a lyric programme synthesising the distinctive styles and subjects of his illustrious predecessors. In so doing, Horace figuratively and literally inserts himself among these nine ‘lyric bards’ in ironic fulfilment of his own request for canonisation, with which the poem concludes. His programmatic priamel therefore harmonises archaic subject-matter and Hellenistic method in a manner which sets the tone for the entire project to follow.
Moduli of wild Higgs bundles on with -actions
Authors: FREDRICKSON LAURA , NEITZKE ANDREW 
Published: June 2021

AbstractWe study a set $\mathcal{M}_{K,N}$ parameterising filtered SL(K)-Higgs bundles over $\mathbb{C}P^1$ with an irregular singularity at $z = \infty$, such that the eigenvalues of the Higgs field grow like $\vert \lambda \vert \sim \vert z^{N/K} \mathrm{d}z \vert$, where K and N are coprime. $\mathcal{M}_{K,N}$ carries a $\mathbb{C}^\times$-action analogous to the famous $\mathbb{C}^\times$-action introduced by Hitchin on the moduli spaces of Higgs bundles over compact curves. The construction of this $\mathbb{C}^\times$-action on $\mathcal{M}_{K,N}$ involves the rotation automorphism of the base $\mathbb{C}P^1$. We classify the fixed points of this $\mathbb{C}^\times$-action, and exhibit a curious 1-1 correspondence between these fixed points and certain representations of the vertex algebra

$\mathcal{W}_K$

; in particular we have the relation

$\mu = {k-1-c_{\mathrm{eff}}}/{12}$

, where

$\mu$

is a regulated version of the L2 norm of the Higgs field, and

$c_{\mathrm{eff}}$

is the effective Virasoro central charge of the corresponding W-algebra representation. We also discuss a Białynicki–Birula-type decomposition of

$\mathcal{M}_{K,N}$

, where the strata are labeled by isomorphism classes of the underlying filtered vector bundles.
Two Immersive Virtual Reality Tasks for the Assessment of Spatial Orientation in Older Adults with and Without Cognitive Impairment: Concurrent Validity, Group Comparison, and Accuracy Results
Authors: da Costa Raquel Quimas Molina , Pompeu José Eduardo , Moretto Emerson , Silva Juliana Magalhães , dos Santos Michelle Didone , Nitrini Ricardo , Brucki Sonia Maria Dozzi 
Published: June 2021

AbstractObjective:Spatial disorientation is common in Alzheimer’s disease (AD), Mild Cognitive Impairment (MCI), and preclinical individuals with AD biomarkers. However, traditional neuropsychological tests lack ecological validity for the assessment of spatial orientation and to date, there is still no gold standard. The current study aimed to determine the validity and accuracy of two virtual reality tasks for the assessment of spatial orientation.Methods:We adapted two spatial orientation tasks to immersive virtual environments: a “survey to route” task in which participants had to transfer information from a map to their body position within a maze [Spatial Orientation in Immersive Virtual Environment Test (SOIVET) Maze], and an allocentric-type, route learning task, with well-established topographic landmarks (SOIVET Route). A total of 19 MCI patients and 29 cognitively healthy older adults aged 61–92 participated in this study. Regular neuropsychological assessments were used for correlation analysis and participant performances were compared between groups. Receiver Operating Characteristic (ROC) curve analysis was performed for accuracy.Results:The SOIVET Maze correlated with measures of visuoperception, mental rotation, and planning, and was not related to age, educational level, or technology use profile. The SOIVET Route immediate correlated with measures of mental rotation, memory, and visuoconstruction, and was influenced only by education. Both tasks significantly differentiated MCI and control groups, and demonstrated moderate accuracy for the MCI diagnosis.Conclusion:Traditional neuropsychological assessment presents limitations and immersive environments allow for the reproduction of complex cognitive processes. The two immersive virtual reality tasks are valid tools for the assessment of spatial orientation and should be considered for cognitive assessments of older adults.
Correlative Site-Specific Sample Preparation for Atom Probe Tomography on Complex Microstructures
Authors: Campo Schneider Lucía Paula , Barrirero Jenifer , Pauly Christoph , Guitar Agustina , Mücklich Frank 
Published: June 2021

Abstract
Site-specific specimen preparation for atom probe tomography (APT) is a challenging task. Small features need to be located using a suitable imaging technique and captured within a volume of less than 0.01 μm3. Correlative microscopy has shown to be helpful for target preparation as well as to gain complementary information about the material. Current strategies developed in that direction can be highly time-consuming and not always ensure the correct site extraction in complex microstructures. In this work, we present a methodology to study grain boundaries and interfaces in martensitic steels by combining electron backscattered diffraction, transmission Kikuchi diffraction (TKD), and APT. Furthermore, we include the design of a sample holder that allows to perform TKD and scanning transmission electron microscopy on the specimen during preparation without breaking the vacuum of the scanning electron microscope/focused ion beam workstation. We show a case study where a prior austenite grain boundary is traced from the bulk material to the apex of the APT specimen. The presence of contamination due to the specimen exposure to the electron beam and the use of plasma cleaning to minimize it are discussed.
High‐Precision Relocation With the Burial Depths of the North Korean Underground Nuclear Explosions by Combining Pn and Pg Differential Traveltimes
Authors: Yang G. , Zhao L. F. , Xie X. B. , Zhang L. , Yao Z. X. 
Published: June 2021

AbstractIn seismic nuclear monitoring, an accurate source depth is an important prerequisite for reliably estimating the explosive yield. Relative location methods are often used for this purpose. However, the conventional method based on regional Pn waves usually fails to give satisfactory constraints on the source depth, mainly due to the strong trade‐off between the burial depth and origin time. This study explores a high‐precision relative location method to simultaneously determine the relative epicenter and source elevation by using differential traveltimes from both downward‐takeoff Pn waves and horizontal‐takeoff Pg waves. The properties of both Pg and Pn waves, including the consistency between waveforms, the reliability of differential traveltime measurements, and their sensitivities to epicenter and depth variations, are investigated. By jointly applying both types of waveform data, the proposed method significantly enhances the constraint on the source depth variation. This method is applied to regional seismic data collected from China, South Korea, and Japan to determine the relative epicenters, origin times and relative burial depths of six North Korean underground nuclear explosions. The source depths are then used to provide burial‐depth corrections to estimate the explosive yields. The depths of the six North Korean nuclear explosions detonated on October 2006, May 2009, February 2013, January 2016, September 2016, and September 2017 are determined to be 330, 540, 506, 468, 521, and 570 m, respectively, and their yields after burial depth corrections are 1.6, 5.7, 13.4, 12.6, 21.7, and 225.7 kt, respectively.
Influence of Different ENSO Types on Tropical Cyclone Rapid Intensification Over the Western North Pacific
Authors: Guo Yi‐Peng , Tan Zhe‐Min 
Published: June 2021

AbstractThis study investigates the influence of different types of El Niño‐Southern Oscillation (ENSO) on the properties of tropical cyclone (TC) rapid intensification (RI) over the western North Pacific (WNP). The RI numbers during all types of ENSO events have no significant difference from that of neutral years, except that eastern Pacific (EP) El Niño corresponds to fewer RI cases. The most robust response of RI properties is occurrence position. The mean RI occurrence position in La Niña events shifts northwards by about 2° in latitude during the peak TC season (July–September), which may be related to the northwestward shift of TC genesis positions. On the other hand, the mean RI occurrence positions during EP El Niño and La Niña events in the late TC season (October–December) shift westwards by about 10° and 14° in longitude, respectively. This westward shift in RI occurrence positions is mainly caused by the favorable conditions over the western part of the WNP in the late TC season. During October–December, EP El Niño shifts to a La Niña phase and warms the upper ocean of the western part of the WNP. La Niña events result in similar upper ocean conditions because they maintain negative phases during October–December. The warmed upper ocean is also accompanied by a moistened mid‐troposphere and weakened vertical wind shear, which are favorable for RI occurrence.