bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comparison of Treatment Options for Type 1 and Type 2 Caesarean Scar Pregnancy: A Retrospective Case Series Study
Authors: Shen Fanghua , Lv Hongdao , Wang Liming , Zhao Ruiheng , Tong Mancy , Lee Arier Chi-Lun , Guo Fang , Chen Qi 
Published: June 2021

Background: There is currently no agreement on the optimal management of caesarean scar pregnancy. Caesarean scar pregnancy is currently categorised into two subtypes according to the site of implantation. This may consequently result in the difference in treatment options. However, the comparison of the success rate of each treatment option according to the subtypes has not been fully investigated.Methods: 71 patients who were treated by uterine curettage (D and C), or uterine artery embolization with curettage (UAE) or hysteroscopy in conjunction with laparoscopy between January 2016 and March 2020 were included. Data on maternal age, gestational sac age, the sac diameter, the interval between two pregnancies, the number of previous caesarean sections, amount of bleeding and β-hCG levels were collected and analysed dependent on the subtypes.Results: There was no difference in the clinical parameters of the cases who received different options of treatment, as well as no difference in the clinical parameters between type 1 and type 2 caesarean scar pregnancy. The primary success rate for type 1 caesarean scar pregnancy by D and C, or UAE, or hysteroscopy in conjunction with laparoscopy was 95, or 100 or 100%, respectively. The primary success rate for type 2 caesarean scar pregnancy by D and C, or UAE, or hysteroscopy in conjunction with laparoscopy was 27, or 67, or 95% respectively.Conclusion: Our data demonstrates that hysteroscopy in conjunction with laparoscopy for type 2 caesarean scar pregnancy was the most successful compared to other options, but for type 1 caesarean scar pregnancy, D and C could be the cost-effective option.
308-nm Excimer Lamp vs. Combination of 308-nm Excimer Lamp and 10% Liquor Carbonis Detergens in Patients With Scalp Psoriasis: A Randomized, Single-Blinded, Controlled Trial
Authors: Rattanakaemakorn Ploysyne , Triyangkulsri Korn , Iamsumang Wimolsiri , Suchonwanit Poonkiat 
Published: June 2021

Background: Scalp psoriasis is usually refractory to treatment. Excimer devices have been proved to be a promising therapeutic option in psoriasis. Greater efficacy of phototherapy can be achieved by concurrent use of coal tar derivatives.Objective: We aimed to compare efficacy and safety between 308-nm excimer lamp monotherapy and a combination of 308-nm excimer lamp and 10% liquor carbonis detergens in the treatment of scalp psoriasis.Methods: In this randomized, evaluator-blinded, prospective, comparative study, 30 patients with scalp psoriasis received either 308-nm excimer lamp monotherapy or a combination of 308-nm excimer lamp and 10% liquor carbonis detergens twice per week until complete remission of the scalp or for a total of 30 sessions. Efficacy was evaluated by the improvement of Psoriasis Scalp Severity Index (PSSI) score, itch score, and Scalpdex score.Results: Both treatments induced significant improvement in PSSI score with greater reduction observed in the combination group. At 30th visit, a 75% reduction in PSSI (PSSI75) was attained by 4 (28.6%) and 9 (69.2%) patients treated with monotherapy and combination therapy, respectively (P &lt; 0.05).Conclusions: Excimer lamp is well-tolerated in patients with scalp psoriasis and liquor carbonis detergens can be used as a combination therapy to improve the efficacy of excimer lamp.
Cost-Effectiveness Analysis of Local Treatment in Oligometastatic Disease
Authors: Mehrens Dirk , Unterrainer Marcus , Corradini Stefanie , Niyazi Maximilian , Manapov Farkhad , Westphalen C. Benedikt , Froelich Matthias F. , Wildgruber Moritz , Seidensticker Max , Ricke Jens , Rübenthaler Johannes , Kunz Wolfgang G. 
Published: June 2021

BackgroundIn certain malignancies, patients with oligometastatic disease benefit from radical ablative or surgical treatment. The SABR-COMET trial demonstrated a survival benefit for oligometastatic patients randomized to local stereotactic ablative radiation (SABR) compared to patients receiving standard care (SC) alone. Our aim was to determine the cost-effectiveness of SABR.Materials and MethodsA decision model based on partitioned survival simulations estimated costs and quality-adjusted life years (QALY) associated with both strategies in a United States setting from a health care perspective. Analyses were performed over the trial duration of six years as well as a long-term horizon of 16 years. Model input parameters were based on the SABR-COMET trial data as well as best available and most recent data provided in the published literature. An annual discount of 3% for costs was implemented in the analysis. All costs were adjusted to 2019 US Dollars according to the United States Consumer Price Index. SABR costs were reported with an average of $11,700 per treatment. Deterministic and probabilistic sensitivity analyses were performed. Incremental costs, effectiveness, and cost-effectiveness ratios (ICER) were calculated. The willingness-to-pay (WTP) threshold was set to $100,000/QALY.ResultsBased on increased overall and progression-free survival, the SABR group showed 0.78 incremental QALYs over the trial duration and 1.34 incremental QALYs over the long-term analysis. Treatment with SABR led to a marginal increase in costs compared to SC alone (SABR: $304,656; SC: $303,523 for 6 years; ICER $1,446/QALY and SABR: $402,888; SC: $350,708 for long-term analysis; ICER $38,874/QALY). Therapy with SABR remained cost-effective until treatment costs of $88,969 over the trial duration (i.e. 7.6 times the average cost). Sensitivity analysis identified a strong model impact for ongoing annual costs of oligo- and polymetastatic disease states.ConclusionOur analysis suggests that local treatment with SABR adds QALYs for patients with certain oligometastatic cancers and represents an intermediate- and long-term cost-effective treatment strategy.
Case Report: Pink Urine Syndrome Following Exposure to Propofol: A Rare, Impressive but Benign Complication
Authors: Zhang Fangwei , Zhu Xing , Zhang Hongbo , Xu Lin , Wu Weiguo , Hu Xuelei , Zhou Haipeng , Wei Penghui , Li Jianjun 
Published: June 2021

Drug-induced changes in urine color induced by drugs may have clinical significance. Pink urine syndrome (PUS), which has been associated with urinary uric acid (UA) disorders, is most frequently reported in patients with morbid obesity undergoing gastric bypass surgery and/or from propofol anesthesia use in those who potentially have preexisting UA metabolism disorders. However, PUS has rarely occurred following exposure to propofol in non-obese patients, and literature on long-term follow-up after PUS is scarce. We report a case of PUS induced by propofol in a previously healthy non-obese woman after undergoing thoracoscopic wedge resection of pulmonary nodules under general anesthesia using propofol. The patient suddenly developed pink urine 4 h after surgery. A pink sediment rapidly precipitated at the bottom of the test tube following centrifugation of the urine. Amorphous, colorless UA-like crystals were identified under a polarizing microscope. The diagnosis of PUS was confirmed by examining the urinary UA concentration. The patient recovered and as followed-up for 1 month, during which she did not experience any urinary complications. To our knowledge, this is the first report to describe in detail a case of PUS caused by propofol in a non-obese patient with follow-up. PUS is usually benign and can resolve by rapidly on administering lactated Ringer’s solution; however, the potential risk of urinary complications, particularly UA lithiasis, should be fully realized.
Association of Gender With Outcomes in Hospitalized Patients With 2019-nCoV Infection in Wuhan
Authors: Han Huiwu , Peng Xiaobei , Zheng Fan , Deng Guiyuan , Cheng Xiaocui , Peng Liming 
Published: June 2021

Aim: The aim of this study was to analyze the association of gender with psychological status and clinical outcomes among patients with 2019-nCoV infection to provide new directions for the prevention and control of the pandemic.Methods: One hundred and thirty-eight patients with confirmed 2019-nCoV infection at Wuhan Union Hospital, between February 8 and March 31, 2020, were included in the study analysis. General information and data on clinical characteristics were collected from patients' medical records. Participants' responses to self-report measures of psychological status were also collected.Results: Anxiety levels, depression levels, and recovery rates were significantly higher among women compared to men. Conversely, chronic disease history and smoking rates, dry cough incidence, C-reactive protein levels, and disease severity were significantly higher among men than women (p &lt; 0.05).Conclusion: Female patients experienced more severe psychological issues, due to higher levels of anxiety and stress, than male patients; indicating that more attention should be paid to the psychological care of female patients. In contrast, the general condition of male patients was more severe, particularly among elderly male patients with a history of chronic disease and smoking, suggesting that, to prevent and control 2019-nCoV infection, male patients should be encouraged to quit smoking as soon as possible to reduce the risk of severe pneumonia.
Maternal Pre-conception Body Mass Index and Fasting Plasma Glucose With the Risk of Pre-term Birth: A Cohort Study Including 4.9 Million Chinese Women
Authors: Xu Qin , Zhou Qiongjie , Yang Ying , Liu Fangchao , Wang Long , Wang Qiaomei , Shen Haiping , Xu Zongyu , Zhang Yiping , Yan Donghai , Peng Zuoqi , He Yuan , Wang Yuanyuan , Zhang Ya , Zhang Hongguang , Ma Xu , Li Xiaotian 
Published: June 2021

Background:To evaluate the associations of pre-conception body mass index (BMI), fasting plasma glucose (FPG) alone and their combination with pre-term birth (PTB) risk.Methods:We conducted a population-based retrospective cohort study with 4,987,129 reproductive-aged women, who participated in National Free Pre-Pregnancy Checkups Project in 2013–2016 and had a singleton delivery before December 2017 in China. All data analyses were conducted in 2018–2021.Results:A total of 339,662 (6.81%) women had pre-term deliveries. Compared with women with normal weight and normal glucose, underweight and normal weight were associated with PTB among hypoglycemia women, the adjusted odd ratios (aORs) were 1.24 (95% CI: 1.05–1.48) and 1.16 (95% CI: 1.07–1.25), respectively; underweight, overweight and obesity were associated with PTB among women with normal glucose, the aORs were 1.09 (95% CI: 1.08–1.10), 1.06 (95% CI: 1.05–1.07) and 1.08 (95% CI: 1.05–1.12), respectively; all the BMI groups were significantly associated with PTB among women with pre-diabetes or diabetes (P&lt; 0.05). The dose-response relationships of BMI with PTB varied in different FPG level, with U-shaped curve in normal glucose and pre-diabetes women, J-shaped in diabetes women, L-shaped in hypoglycemia women. For FPG with PTB, the dose-response relationships were U-shaped in normal weight, overweight, and obesity women, and L-shaped in underweight women.Conclusion:We found that the associations of PTB with BMI varied with levels of FPG, and associations of PTB with FPG varied with levels of BMI. There was a synergistic effect on PTB risk due to abnormal weight and glycemia besides a conventional main effect derived from either of them. Achieving desirable weight and glucose control before conception should be advised.
Addressing Cancer Screening Inequities by Promoting Cancer Prevention Knowledge, Awareness, Self-Efficacy, and Screening Uptake Among Low-Income and Illiterate Immigrant Women in France
Authors: De Jesus Maria , Rodrigue Christelle M. , Rahmani Sarah , Balamou Christian 
Published: June 2021

Objective: Cancer screening rates are suboptimal for disadvantaged populations in France, yet little evidence exists on their cancer-related knowledge and screening barriers. The main objective of this study was to examine cancer-related knowledge, awareness, self-efficacy, and perceptions of screening barriers among low-income, illiterate immigrant women in France following an 8-weeks cancer educational intervention.Methods: Semi-structured qualitative interviews were conducted with 164 female participants in the Ain department of France between January 2019 and March 2020. Adopting the Health Belief Model as an intervention and analytic framework, salient themes were identified using qualitative thematic analysis.Results: Increased levels of perceived susceptibility to and perceived severity of cancer contributed to higher motivation to get screened. Barriers to screening included low French proficiency, shame surrounding illiteracy, and constant worries due to precarious living conditions. Perceived benefits (e.g., valuing one’s health and health-promoting behaviors), cues to action from a trusted source, and greater self-efficacy (e.g., more autonomous in healthcare-seeking) outweighed perceived barriers, including cultural barriers.Conclusions: Implications include developing audience-responsive targeted cancer screening communication strategies and educational materials to increase screening rates and reduce cancer and cancer screening inequities.
The Short story of Nagam in the view of Magical Realism
Authors: B Umarani 
Published: June 2021

The various theories and theories and policies are emerging in the literary world. They help to approach literature with a new perspective and give them a new form. In that sense, it is conceivable that the theory of realism has succeeded in the endeavors in the realm of Tamil literature. It has a footprint and an impression in numerous artistic classifications like in many literary categories such as short stories, novels, poetry, drama, etc. In this way, the article inspects the utilization of the mystical realities in the short story "Nagam" to explain the contemporary issues.
Theological principle and doctrine emphasized by Thiruvarutha
Authors: B Vijayakumar 
Published: June 2021

Vadalur Vallalar is one of the most remarkable people who have contributed literature to the upliftment of human society. He has a unique composition called 'Thiru Arutpa'. He identified God as a blessing and wanted other beings to see God. He showed the world the principle of the spirit, the highest goal, the spirit of the spirit, by saying that the way to reach God is the life-giving principle of life. This article is a description of the principles and principles of the theology in his thiruvarutpa.
Perlindungan Hukum Tenaga Kerja Di PHK Sepihak Oleh Rs.Royal Taruma (Studi Kasus Putusan Nomor:155/Pdt.Sus-Phi/201/Pn.Jkt.Pst)
Authors: Miharja Marjan , Yudianto Yudianto , Robekha Jamiatur 
Published: June 2021

Pelaksanaan pemutusan hubungan kerja yang dilakukan oleh perusahaan harus sesuai dengan undang- undang no 13 tahun 2003 tentang ketenagakerjaan yang mennyatakan bahwa pemutusan hubungan kerja dilakukan dalam beberapa proses yaitu mengadakan musyawarah antara karyawan dengan perusahaan, bila menemui jalan buntu maka jalan terakhir adalah melalui pengadilan untuk memutuskan perkara. Akan tetapi pada kenyataanya sering terjadi pemberhentian dengan pemecatan tanpa adanya alasan yang jelas, Seharusnya pemecatan karyawan harus berdasar kepada peraturan dan perundang- undangan karena setiap karyawan mendapat perlindungan hukum sesuai dengan statusnya. Permasalahan dalam tulisan ini yaitu Bagaimanakah perlindungan hukum terhadap tenaga kerja yang di PHK secara sepihak menurut Undang-undang No. 13 Tahun 2003 tentang Ketenagakerjaan? Dan Bagaimana pertimbangan hakim dalam putusan nomor: 155/Pdt.Sus-PHI/2015/PN.JKT.PST? Dalam karya ilmiah ini metode penelitian yang digunakan adalah penelitian hukum normatif yaitu mengandalkan data sekunder sebagai sumber data utama. Hasil penelitian menunjukkan bahwa dalam putusan Majelis Hakim pada putusan Nomor 155/Pdt.Sus-PHI/2015/PN.JKT.PST, dalam pertimbanganya menyebutkan bahwa Pemutusan Hubungan Kerja secara sepihak oleh Rs. Royal Taruma terhadap Analisa Paulina Kartika melanggar hukum dan tidak sesuai dengan Undang-undang Nomor 13 tahun 2003 tentang ketenagakerjaan. Dan tanggung jawab perusahaan terhadap tenaga kerja yang telah diPHK dimana dalam undang-undang mengharuskan atau mewajibkan perusahaan untuk memberikan uang pesangon, uang penghargaan, dan uang penggantian hak.
Estimasi Reproduction Number Model Matematika Penyebaran Malaria di Sumba Tengah, Indonesia
Authors: Banni Ervin Mawo , Kleden Maria A , Lobo Maria , Ndii Meksianis Zadrak 
Published: June 2021

Malaria is transmitted via a bite of mosquitoes and it is dangerous if it is not properly treated. Mathematical modeling can be formulated to understand the disease transmission dynamics. In this paper, a mathematical model with an awareness program has been formulated and the reproduction number has been estimated against the data from Weeluri Health Center, Mamboro District, Central Sumba. The calculation showed that the reproduction number is R0 = 1.2562. Results showed that if the efficacy of the awareness program is lower than 20%, the reproduction number is still above unity. If the efficacy of the awareness program is higher than 20%, the reproduction number is lower than unity. This implies that the efficacy of awareness programs is the key to the success of Malaria eradication.
EFFICIENCY ANALYSIS OF THE ON-GRID SOLAR POWER PLANT IN THE CHECHEN REPUBLIC
Authors: Саламов И. Х. 
Published: June 2021

Одной из актуальных задач в развитии возобновляемой энергетики является активное внедрение экологически чистых энергетических систем в частный сектор. В работе представлены результаты анализа выработки и экономической эффективности солнечной энергетической установки, работающей в частном секторе параллельно с централизованной электросетью. Исследованы методы прогнозирования выработки фотоэлектрических модулей в различных географических и климатических условиях. На основе анализа данных о выработке солнечной энергоустановки проведен сравнительный анализ расчетных и фактических характеристик в реальных эксплуатационных условиях. С использованием данных об уровне солнечной радиации на территории Чеченской Республики, а также данных о тарифах на электроэнергию в регионе, спрогнозирован экономический эффект от использования сетевой солнечной энергоустановки.
One of the urgent tasks in the development of renewable energy is the active introduction of environmentally friendly energy systems in the private sector. The article presents the results of an analysis of the generation and economic efficiency of a solar power plant operating in the private sector in parallel with a centralized electric grid. Studied methods of predicting the efficiency of photovoltaic modules in different geographical and climatic conditions. Based on the analysis of data on the generation of solar power plants, a comparative analysis of the calculated and actual characteristics in real operating conditions is carried out. Using data on the level of solar radiation in the Chechen Republic, as well as data on electricity tariffs in the region, the economic effect of the use of a grid solar power plant is predicted.
TECHNOLOGIES OF FORMATION VIRTUAL LABORATORY PRACTICAL WORK
Authors: Алисултанова Э. Д. , Моисеенко Н. А. 
Published: June 2021

В данной статье рассматривается технологический подход к разработке электронного практикума, который представляет собой комплекс заданий, представленных в комфортном для восприятия и закрепления обучающимися теоретических и практических знаний по учебной дисциплине. В ходе исследования охарактеризована предметная область, проанализированы системы для создания и размещения электронных лабораторных практикумов, описано информационное, программное и техническое обеспечение, необходимое для реализации разработки.
In this article technological approach to development of an electronic practical work which represents a complex of the tasks presented in comfortable for perception and fixing with students of theoretical and practical knowledge of a subject matter is considered. During the research the subject domain is characterized, systems for creation and placement of electronic laboratory practical works are analysed, the information, program and technical support necessary for development realization is described.
FORMATION OF THE STRUCTURE OF MULTICOMPONENT ALKALI BASIC KNITTING SYSTEMS
Authors: Муртазаев С-А. Ю. , Саламанова М. Ш. 
Published: June 2021

Использование бетонов на чистом портландцементе сегодня не столь актуально, так как ведущие научные школы мира в этом направлении стараются получать композиты на смешанных вяжущих, путем замены дорогого и энергоемкого портландцемента. Поэтому разработка современных эффективных композитов на основе бесклинкерных вяжущих щелочной активации, безусловно, является актуальной проблемой. В основу проведенных исследований положен современный технологический прием, способствующий получению прочного и долговечного цементного камня, без применения традиционного портландцемента. Результаты проведенных исследований подтверждают совместимость всех компонентов многокомпонентной системы «минеральный порошок - щелочной затворитель - ПАВ», а предлагаемый технологический прием позволит получать прочные и долговечные строительные композиты по бесклинкерной технологии, без применения дорогого и энергоемкого портландцемента. Работа выполнена в рамках исследований по реализации научного проекта № 18-48-200001 «Высококачественные бетоны с повышенными эксплуатационными свойствами на основе местного природного и техногенного сырья», получившего поддержку Российского фонда фундаментальных исследований» (РФФИ).
The use of concrete on pure Portland cement is not so relevant today, as the leading scientific schools of the world in this direction are trying to obtain composites on mixed binders by replacing expensive and energy-intensive Portland cement. Therefore, the development of modern effective composites based on clinkerless alkaline binders is certainly an urgent problem. The research is based on a modern technological method that contributes to the production of strong and durable cement stone, without the use of traditional Portland cement. The results of the studies confirm the compatibility of all components of the multicomponent system “mineral powder - alkaline caster - surfactant”, and the proposed technological method will allow to obtain strong and durable building composites using clinker-free technology, without the use of expensive and energy-intensive Portland cement. The work was implemented as part of research on the fulfillment of scientific project No. 18-48-200001 “High-quality concrete with enhanced performance properties based on local natural and secondary raw materials,” which received support from the Russian Foundation for Fundamental Research (RFFR).