bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the effect of carbamazepine on the concentration of vitellogenin in Pseudoplatystoma magdaleniatum
Authors: Ortiz Sylvia María Cacua , Aguirre Néstor J. , Peñuela Gustavo A. 
Published: September 2021

Abstract
Carbamazepine is a pharmaceutical used in patients with seizures and bipolar disorder, which has been found in wastewater and many water resources. This is due to the inadequate disposal of pharmaceutical waste and the lack of treatment of municipal wastewater, as is the case in Colombia. The two main hydrographic basins of Colombia are the Cauca and Magdalena rivers, which are inhabited by the endemic species Striped Catfish (Pseudoplatystoma magdaleniatum). This has become an endangered species for various reasons, including the high contamination level of these rivers. In 2019, mature adult P. magdaleniatum of both sexes were caught in the Cauca river in Colombia. This was in order to assess the concentration of vitellogenin, as a biomarker of endocrine disruption, resulting from exposure to different levels of concentration of the emerging contaminant carbamazepine for 4 months. These tests were carried out in a fish farm. A significant decrease in the vitellogenin concentration was verified in females at concentrations of 25 µg l-1 and 50 µg l-1, and in males at 50 µg l-1 of carbamazepine, with a significance level of p˂0.05. Carbamazepine could cause a negative feedback in gonadotropin secretion, acting as an estrogen mimicker that causes a decrease in the level of vitellogenin.
Classification ofTypha-dominated wetlands using airborne hyperspectral imagery along Lake Ontario, USA
Authors: Suir Glenn M. , Wilcox Douglas A. , Reif Molly 
Published: September 2021

AbstractShoreline wetlands along Lake Ontario are valuable, multi-functional resources that have historically provided large numbers of important ecosystem goods and services. However, alterations to the lake’s natural hydrologic regime have impacted traditional meadow marsh in the wetlands, resulting in competition and colonization by dense and aggressive Typha angustifolia and Typha x glauca (Cattails). The shift to a Typha-dominated landscape resulted in an array of negative impacts, including increased Typha density, substantial decreases in plant species richness and diversity, and altered habitat and changes in associated ecosystem services. Successful long-term adaptive management of these wetland resources requires timely and accurate monitoring. Historically, wetland landscapes have been surveyed and mapped using field-based surveys and/or photointerpretation. However, given their resource- and cost-intensive nature, these methods are often prohibitively time- and labor-consuming or geographically limited. Other remote sensing applications can provide more rapid and efficient assessments when evaluating wetland change trajectories or analyzing direct and indirect impacts across larger spatial and temporal scales. The primary goal of this study was to develop and describe methodology using U.S. Army Corps of Engineers National Coastal Mapping Program hyperspectral imagery, light detection and ranging data, and high-spatial resolution true-color imagery to provide updated wetland classifications for Lake Ontario coastal wetlands. This study used existing field-collected vegetation survey data (Great Lakes Coastal Wetland Monitoring Program), ancillary imagery, and existing classification information as training data for a supervised classification approach. These data were used along with a generalized wetland schema (classes based on physical and biological gradients: elevation, Typha, meadow marsh, mixed emergent, upland vegetation) to generate wetland classification data with Kappa values near 0.85. Ultimately, these data and methods provide helpful knowledge elements that will allow for more efficient inventorying and monitoring of Great Lake resources, forecasting of resource condition and stability, and adaptive management strategies.
Tennessee Williams’s Misunderstood ‘memory play’: Re-Imagining Amanda Wingfield in The Glass Menagerie
Authors: Romero Ramón Espejo 
Published: September 2021

Abstract
Tennessee Williams famously called The Glass Menagerie a ‘memory play’. This remark has been consistently overlooked or misinterpreted by critics, unleashing a tradition of approaching the play in a rather confusing fashion concerning who the characters are and how the playwright uses them. This paper engages with the character of Amanda. First of all, I will trace major transformations in the conception of characters throughout twentieth-century drama, providing background for Williams’s attempt to redefine major aspects of a playwright’s craft such as what a ‘character’ is. Secondly, I will survey a critical tradition surrounding Tom Wingfield’s mother and consider major views concerning the character. Recurrent in them, as my analysis indicates, is the failure to acknowledge her as a tool for the ‘memory work’ Tom carries out. The character is subsequently posited as a fluid entity that helps Tom (and Williams) make sense of the past and explore how their families shaped who they were. As opposed to a realistic play, where so much is given at the start, a ‘memory play’, as Williams seems to have conceived it, remains a cry for the reader to join the playwright in a common search for meaning, one that utilizes, rather than just displays, characters in order to reach standpoints that are far from fixed and immutable.
Isolation of microglia from retinas of chronic ocular hypertensive rats
Authors: Zhong Huimin , Yu Huan , Sun Jun , Chen Junjue , Huang Shouyue , Huang Ping , Liu Xiaohong , Zhong Yisheng 
Published: September 2021

Abstract
Microglia are the principal glial cells involved in the processes of immune inflammation within both retina and optic nerve, especially under the context of glaucomatous neuropathy. Considering the distinguishing role of retinal microglia in glaucoma and the lack of established protocol for microglia isolation from animal glaucoma model, the present study aimed to develop and validate a method with characteristics of both simplicity and efficiency for retinal microglia isolation from chronic ocular hypertensive (COH) rats. A Percoll gradient of various concentrations was used to separate microglia from whole retinal cells of the COH rats and control group. The finally isolated microglia were identified by CD11b and Iba-1 immunofluorescence staining, and the cell viability was determined by trypan blue staining. Additionally, the proportion of microglia in the whole retina cells was identified by flow cytometry. Results showed that the survival rates of isolated retinal microglia with the Percoll gradient method were 67.2 ± 4% and 67.6 ± 3% in control and COH groups, respectively. The proportion of the microglia population in the whole retinal cells was about 0.4–0.93%. To conclude, the present study confirmed that the application of Percoll gradient could effectively separate microglia from retinas of COH rats, which will probably enrich the tool kit for basic researchers of glaucoma specialty and help with scientific investigations.
Production and characterization of thermoplastic elastomer foams based on the styrene–ethylene–butylene–styrene (SEBS) rubber and thermoplastic material
Authors: Kıroğlu Ceren , Kızılcan Nilgün 
Published: September 2021

Abstract
Thermoplastic elastomer foams based on styrene–ethylene–butylene–styrene (SEBS)/polypropylene (PP) were produced by using different processing techniques such as extrusion and injection molding to achieve optimized mechanical and thermal properties in terms of strength, elongation, and damping capability. Foaming is a method of introducing gas-filled cells into the material and it is considered an effective way to meet the requirements for higher impact resistance with low density and relatively low hardness. In this study, microspheres were used as a foaming agent and were introduced to the system by using an injection molding machine. They were used in different percentages and ranged from 1 and 3%. They decrease the density of the product thereby lowering the weight and cost. Besides improving damping abilities and decreasing the density, inorganic fillers such as talc, silica, and calcium carbonate were used to increase the mechanical strength, and their effectivity was also investigated. It was observed that a higher amount of foaming agent lowered the density by creating voids in the blend, as expected. The introduction of fillers increases the mechanical properties; however, the density had a negative effect even in the presence of foaming agents. About 3% density reduction can be achieved in the presence of talc and a foaming agent whereas the other fillers had an opposite effect on the density. Accordingly, the impact resistance was affected negatively because of the stiffness of the filler materials, and the highest Izod impact value was 50.2 kJ/m2. The elastic modulus values for foamed samples and filled with CaCO3, talc, and silica were 808, 681, and 552 MPa respectively. Combining foaming and thermoplastic elastomers (TPEs) offers a wide variety of possibilities to new and existing applications. In addition to low hardness and density, foaming provides better damping ability thanks to its morphological structure.
Incorporating the multi-level nature of the constructicon into hypothesis testing
Authors: Pijpops Dirk , Speelman Dirk , Van de Velde Freek , Grondelaers Stefan 
Published: September 2021

AbstractConstruction grammar organizes its basic elements of description, its constructions, into networks that range from concrete, lexically-filled constructions to fully schematic ones, with several levels of partially schematic constructions in between. However, only few corpus studies with a constructionist background take this multi-level nature fully into account. In this paper, we argue that understanding language variation can be advanced considerably by systematically formulating and testing hypotheses at various levels in the constructional network. To illustrate the approach, we present a corpus study of the Dutchnaar-alternation. It is found that this alternation primarily functions at an intermediate level in the constructional network.
Value addition study on coker kero for producing alpha olefin and alkyl benzene
Authors: Tripathi Deependra , Singh Raj K. , Kumar Kamal , Singh Udai P. 
Published: September 2021

Abstract
Coker kero stream is obtained from delayed coking which contains saturates with alpha olefins and PNA compounds which was physicochemical characterised. The fractions present in coker kero may be used further for value added products such as alkyl benzene and naphthalene etc. The study described potential of coker kero via aromatics and non-aromatics separation by using liquid-liquid extraction (LLE) with N-methyl pyrrolidone (NMP), acetonitrile and methanol as solvents of different polarity. Methanol imparts best colour improvement as per ASTM D-1500. Beside this, adsorption study on coker kero was performed using fuller’s earth, chalk powder, red ochre and wood-stick’s ash as adsorbents. The adsorption study suggested that fuller’s earth not only separate aromatics and non-aromatics form coker kero, but also acts as a better adsorbent than graphitic carbon (activated charcoal) and is found suitable for colour improvement comparatively. This study inferred the separation of polar components, improvement in the colour, odour and established the stable fuel. FT-IR study suggested that N-methyl Pyrrolidone gives better results comparatively other solvents. HC22 type analysis of coker kero raffinate and extract phase confirm the sharp extraction of coker kero feed using N-Methyl pyrrolidone as it is a good solvent for extraction of aromatics. GCMS and HRMS compositional analysis successfully performed for the coker kero and it is separated aromatic and non-aromatic fractions.
Indexicalidad, gentrificación lingüística y desigualdad social en el proceso de estandarización del gallego
Authors: Recalde Montserrat 
Published: September 2021

Abstract
The aim of this paper is to show the relationship between indexicality, standardization policy and socioeconomic inequalities in the Galician linguistic field (as a minor language of Spain). I will examine the discursive role of Galician elites in the building of indexical orders from the Renaissance movement (19th century) onwards, and its links to the current negative representations of rural Galician. Also, I will explore the relationship between anti-rural prejudices, ideologies of class and standard ideologies, showing how common speakers share the stigmatizing indexical values of the elites, and rural speakers consent to the symbolic violence of which they are victims. Finally, I adapt the concept of gentrification from contemporary urbanism to the linguistic field in order to explain the impact of elitist academic lingualizing discourse on traditional speakers of Galician and also on the value of their varieties in the linguistic market. I support my analysis on the metalinguistic discourse of members of the intellectual elites authorized in the Galician linguistic and cultural field from Renaissance to contemporaneity, attitudinal matched-guise research, and ethnographic studies of the second millennium.
Study on the Relationship between the Bonding Surface and Mechanical Properties of PLA/Epoxy Laminated Composites
Authors: Li C. , Shi X.-J. , Tuo X.-H. , Gong Y.-M. , Guo J. 
Published: September 2021

Abstract
Rule of mixtures (RoMs) of composite materials is continuously modified according to different component materials and their composition forms to play the role of theoretical verification and evaluation. This paper studied the regular relationship between the bonding surface and mechanical performance of the composites. The three bonding surface designs were made into PLA/EP test samples by 3D printing technology. The tensile and bending properties of the composite materials were proved to be stronger than the average of those of their component materials. The mechanical properties show regular changes with the bonding surface and structural design. The bonding surface between components is an important reference information that cannot be ignored for the performance prediction and adjustment of laminated composite materials.
Reverse circadian glucocorticoid treatment in prepubertal children with congenital adrenal hyperplasia
Authors: Dubinski Ilja , Bechtold Dalla-Pozza Susanne , Bidlingmaier Martin , Reisch Nicole , Schmidt Heinrich 
Published: September 2021

Abstract

Objectives
Children with salt-wasting congenital adrenal hyperplasia (CAH) have an impaired function of steroid synthesis pathways. They require therapy with glucocorticoid (GC) and mineralocorticoid hormones to avoid salt-wasting crisis and other complications. Most commonly, children receive hydrocortisone thrice daily with the highest dose in the morning, mimicking the regular physiology. However, reverse circadian treatment (RCT) had been suggested previously. In this study, we aimed to determine the efficacy of RCT in prepubertal children with CAH by comparing the salivary 17-hydroxyprogesterone (s17-OHP) levels individually.

Methods
In this retrospective study, we analyzed the records of children with classical CAH and RCT who were monitored by s17-OHP levels. The study included 23 patients. We identified nine prepubertal children with RCT schemes (three boys and six girls) and compared the s17-OHP levels in the morning, afternoon, and evening. The objective of this study was to demonstrate the non-effectiveness of RCT in terms of lowering the morning s17-OHP concentration. In addition, we compared s17-OHP day profiles in six patients on RCT and non-RCT therapy (intraindividually).

Results
Eight of nine children with RCT showed higher s17-OHP levels in the morning compared to the evening. In addition, none of the children showed a significant deviation of development. Three children were overweight. No adrenal crisis or pubertal development occurred. Comparison of RCT and non-RCT regimens showed no difference in 17-OHP profiles.

Conclusions
Our data do not support the use of RCT schemes for GC replacement in children with CAH due to lack of benefits and unknown long-term risks.
Resistance to cracking of concrete containing waste rubber aggregates under cyclic loading using the acoustic emission technique
Authors: Bu Jingwu , Chen Xudong 
Published: September 2021

Abstract
Recycling rubber aggregates from used grinded tires is a behavior of environmental protection. By performing cyclic flexural tests, this paper explores the effect of rubber aggregate content on the crack propagation of notched concrete beams containing waste rubber aggregates. The crack mouth opening displacement is tested. The acoustic emission technique is applied to detect the damage in the fracture process zone. The crack propagation is evaluated using the critical value of the mode I stress intensity factor. It was found that the crack length and stress intensity factor decrease with the increasing of rubber aggregates content. The crack length and stress intensity factor at failure under constant cyclic loading are larger than those at corresponding post-peak load level. It was observed that the damage evolution curves under cyclic envelope loading can be divided into three stages: initial-quick-stable stages. And they are S-shaped, quick-stable-accelerated curves under constant cyclic loading. Rubber aggregate reduces the acoustic emission activities in concrete specimens. Accumulations of acoustic emission hits, acoustic emission counts and acoustic emission energy are found in accordance with the damage evolution of concrete beam. The relation between damage and accumulative acoustic emission hits is quantified by fitting experimental data. The fitting curves agree well with test results.
Fine structure of low-carbon steel after electrolytic plasma treatment
Authors: Bayatanova Lyaila , Rakhadilov Bauyrzhan , Kurbanbekov Sherzod , Skakov Мazhyn , Popova Natalya 
Published: September 2021

Abstract
This work shows the results of research of the fine and dislocation structure of the transition layer of 18CrNi3Mo low-carbon steel after the influence of electrolytic plasma. Conducted research has shown that the modified steel layer, as a result of carbonitriding, was multiphase. Quantitative estimates were made for carbonitride М23(С,N)6 in various morphological components of α-martensite and on average by material in the transition layer of nitro-cemented steel. It was established that α-phase is tempered martensite after nitrocementation. Released martensite is represented by batch, or lath and lamellar low-temperature and high-temperature martensite. Inside the tempered martensitic crystals, lamellar cementite precipitates are simultaneously present, and residual austenite is found along the boundaries of the martensitic rails and plates of low-temperature martensite. It was determined that inside the crystals of all morphological components of α-martensite there are particles of carbonitride М23(С,N)6.
Strength of carbon fiber/epoxy in sea water
Authors: Uğur Yüncüoğlu Ercüment , Turgut Ince Serdar , Bağcı Eyup 
Published: September 2021

Abstract
Composite materials are widely used in the marine industry. The marine environment, on the other hand, has a significant impact on the strength of composite materials. The tensile strength is adversely affected because the matrix material absorbs water. In this study, the effect of orientation, number of layers and different mediums over time on the tensile strength of the woven carbon fiber reinforced epoxy composite material was investigated experimentally from a comprehensive perspective. The findings of the experiments were subjected to variance analysis. The repeated tests and cross-results of the experimental parameters were found to be compatible with each other. Seawater reduces the tensile strength of composite materials in any case. The tensile strength increased with increasing the number of layers. However, it has been observed that the seawater medium reduces strength when the number of layers increases. At the same time, as orientation angle rises, the seawater medium’s negative effect on strength rises.
Effects of grain size on the performance of brake linings with Al2O3 additives
Authors: Karaca Faruk , Can İlhan 
Published: September 2021

Abstract
International organizations such as the World Health Organization (WHO) and the International Labor Organization (ILO) have called for an end to the use of asbestos and its derivatives in all sectors, primarily due to the negative effects on human and environmental health. For this reason, manufacturing and use of asbestos linings are also prohibited in most developed countries. For this purpose, there are many studies in the literature on the development and research of nonasbestos linings. In the literature, topics such as material content, production, cost, braking performances and mechanical properties of composite linings are commonly encountered. With the technology in the developing world, the working conditions of vehicle elements are getting more difficult. For this reason, during braking, the amount of energy required to be damped against the unit area in the pad surfaces increases, and since the lining surface areas get smaller, the operating temperatures exceed the limits of the material components. Under these conditions, the design of the lining material content is extremely important, taking into account parameters such as load and operating conditions, in order to slow down or stop the vehicle safely. In this study, the braking performance, mechanical and tribological properties of the samples obtained from a number of production processes such as mixing, pre-shaping and pressing of the materials by altering the particle sizes (50 μm, 75 μm and 125 μm) of the filler and friction materials used together with powdered alumina (Al2O3) were investigated. The most suitable parameters were determined as lining material for the samples obtained.
Effect of double-sided friction stir welding on the mechanical and microstructural characteristics of AA5754 aluminium alloy
Authors: Çelik Sare , Tolun Fatmagül 
Published: September 2021

Abstract
AA5754Al alloy is widely used in industry. However, as in the case of all Al alloys, the 5xxx series Al alloys cannot be easily joined through fusion welding techniques. To address this problem, in this study, the effect of double-sided friction stir welding at various tool rotational speeds (450, 710, and 900 rpm), feeding rates (40, 50, and 80 mm × min-1), and tool tilt angles (0°, 1°, 2°) on the welding parameters and mechanical and microstructural characteristics of AA5754 Al alloy was determined. Tensile strength tests and microhardness tests were performed to examine the mechanical properties of the welded specimens. The microstructures of the welded zone were examined by obtaining optical microscopy and scanning electron microscopy images. The tensile test results indicated that the specimens exhibited the highest welding performance of 95.17 % at a tool rotational speed, feed rate, and tool tilt angle of 450 rpm, 50 mm × min-1 and 1°, respectively.