bluuebunny/crossref_metadata_2025_split huggingface dataset:
Torque Teno Virus load in lung cancer patients correlates with age but not with tumor stage
Authors: Stefani Dirk , Hegedues Balazs , Collaud Stephane , Zaatar Mohamed , Ploenes Till , Valdivia Daniel , Elsner Carina , Bleekmann Barbara , Widera Marek , Dittmer Ulf , Aigner Clemens 
Published: June 2021

Background
Torque teno virus (TTV) is a ubiquitous non-pathogenic virus, which is suppressed in immunological healthy individuals but replicates in immune compromised patients. Thus, TTV load is a suitable biomarker for monitoring the immunosuppression also in lung transplant recipients. Since little is known about the changes of TTV load in lung cancer patients, we analyzed TTV plasma DNA levels in lung cancer patients and its perioperative changes after lung cancer surgery.

Material and methods
Patients with lung cancer and non-malignant nodules as control group were included prospectively. TTV DNA levels were measured by quantiative PCR using DNA isolated from patients plasma and correlated with routine circulating biomarkers and clinicopathological variables.

Results
47 patients (early stage lung cancer n = 30, stage IV lung cancer n = 10, non-malignant nodules n = 7) were included. TTV DNA levels were not detected in seven patients (15%). There was no significant difference between the stage IV cases and the preoperative TTV plasma DNA levels in patients with early stage lung cancer or non-malignant nodules (p = 0.627). While gender, tumor stage and tumor histology showed no correlation with TTV load patients below 65 years of age had a significantly lower TTV load then older patients (p = 0.022). Regarding routine blood based biomarkers, LDH activity was significantly higher in patients with stage IV lung cancer (p = 0.043), however, TTV load showed no correlation with LDH activity, albumin, hemoglobin, CRP or WBC. Comparing the preoperative, postoperative and discharge day TTV load, no unequivocal pattern in the kinetics were.

Conclusion
Our study suggest that lung cancer has no stage dependent impact on TTV plasma DNA levels and confirms that elderly patients have a significantly higher TTV load. Furthermore, we found no uniform perioperative changes during early stage lung cancer resection on plasma TTV DNA levels.
COVID-19 control strategies and intervention effects in resource limited settings: A modeling study
Authors: Pandey Kiran Raj , Subedee Anup , Khanal Bishesh , Koirala Bhagawan 
Published: June 2021

Introduction
Many countries with weaker health systems are struggling to put together a coherent strategy against the COVID-19 epidemic. We explored COVID-19 control strategies that could offer the greatest benefit in resource limited settings.

Methods
Using an age-structured SEIR model, we explored the effects of COVID-19 control interventions–a lockdown, physical distancing measures, and active case finding (testing and isolation, contact tracing and quarantine)–implemented individually and in combination to control a hypothetical COVID-19 epidemic in Kathmandu (population 2.6 million), Nepal.

Results
A month-long lockdown will delay peak demand for hospital beds by 36 days, as compared to a base scenario of no intervention (peak demand at 108 days (IQR 97-119); a 2 month long lockdown will delay it by 74 days, without any difference in annual mortality, or healthcare demand volume. Year-long physical distancing measures will reduce peak demand to 36% (IQR 23%-46%) and annual morality to 67% (IQR 48%-77%) of base scenario. Following a month long lockdown with ongoing physical distancing measures and an active case finding intervention that detects 5% of the daily infection burden could reduce projected morality and peak demand by more than 99%.

Conclusion
Limited resource settings are best served by a combination of early and aggressive case finding with ongoing physical distancing measures to control the COVID-19 epidemic. A lockdown may be helpful until combination interventions can be put in place but is unlikely to reduce annual mortality or healthcare demand.
PROSPECTS FOR THE DEVELOPMENT OF PARTICIPATORY BUDGETING IN THE ALTAI REGION
Authors: Shevchuk N. A. , Ivleva A. V. 
Published: June 2021

A promising direction for solving the problems of improving life in rural areas is the implementation of the Local Initiatives Support Project, which is the most common and popular practice of initiative budgeting on the whole territory of Russian Federation.
The theoretical basis of participatory budgeting is the republican theory of the organization of society and participatory democracy, which assumes a decentralized collective decision-making that affects the life of the community.
The article considers the history of the development of participatory budgeting in the world, the Russian Federation and the Altai Region in particular, describes the applied procedure of initiative budgeting, and analyzes the implementation of the Local Initiatives Support Project on the example of the Kosikhinsky district, Altai Region.
The performed researches indicate the expansion of the practice of realization the LISP in the Altai Territory.
But already at this stage the authors note the need to improve relations between the project participants and suggest using the experience of implementing the adapted methodology developed by the European University in St. Petersburg and the Committee of Civil Initiatives in the cities of Cherepovets (Vologda region) and Sosnovy Bor (Leningrad region) for this purpose.
Simple pyrolysis of polystyrene into valuable chemicals
Authors: Lu Chao , Xiao Hang , Chen Xi 
Published: June 2021

Abstract
Overuse of polymer products has led to severe environmental problems, which are threatening survival of creatures on earth. It is urgent to tackle enormous polymer wastes with proper cycling methods. Pyrolysis of polymers into high-value chemicals and fuels is displaying great potential to address the white pollution issue. In this study, we focus on chemical recycling of polystyrene, an important polymer in our everyday life, into valuable chemicals through simple pyrolysis strategy under nitrogen protection. It is found that yield of liquid product from polystyrene pyrolysis achieves as high as 76.24%, and there exists single component in the liquid product, which has been identified as styrene through hydrogen nuclear magnetic resonance spectra. Moreover, we propose monomer dissociation mechanism to explain the pyrolysis process of polystyrene based on the structure of polystyrene and experimental results.
Severity of Bronchopulmonary Dysplasia Among Very Preterm Infants in the United States
Authors: Jensen Erik A. , Edwards Erika M. , Greenberg Lucy T. , Soll Roger F. , Ehret Danielle E.Y. , Horbar Jeffrey D. 
Published: June 2021

BACKGROUND AND OBJECTIVESThe Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network recently proposed new, severity-based diagnostic criteria for bronchopulmonary dysplasia (BPD). This study provides the first benchmark epidemiological data applying this definition.METHODSRetrospective cohort study of infants born from 22 to 29 weeks’ gestation in 2018 at 715 US hospitals in the Vermont Oxford Network. Rates of BPD, major neonatal morbidities, and common respiratory therapies, stratified by BPD severity, were determined.RESULTSAmong 24 896 infants, 2574 (10.3%) died before 36 weeks’ postmenstrual age (PMA), 12 198 (49.0%) did not develop BPD, 9192 (36.9%) developed grade 1 or 2 BPD, and 932 (3.7%) developed grade 3 BPD. Rates of mortality before 36 weeks’ PMA and grade 3 BPD decreased from 52.7% and 9.9%, respectively, among infants born at 22 weeks’ gestation to 17.3% and 0.8% among infants born at 29 weeks’ gestation. Grade 1 or 2 BPD peaked in incidence (51.8%) among infants born at 25 weeks’ gestation. The frequency of severe intraventricular hemorrhage or cystic periventricular leukomalacia increased from 4.8% among survivors without BPD to 23.4% among survivors with grade 3 BPD. Similar ranges were observed for late onset sepsis (4.8%–31.4%), surgically treated necrotizing enterocolitis (1.4%–17.1%), severe retinopathy of prematurity (1.2%–23.0%), and home oxygen therapy (2.0%–67.5%).CONCLUSIONSMore than one-half of very preterm infants born in the United States died before 36 weeks’ PMA or developed BPD. Greater BPD severity was associated with more frequent development of major neonatal morbidities, in-hospital mortality, and use of supplemental respiratory support at discharge.
NEW COMBINATIONS AND OTHER TAXONOMIC CHANGES FOR THE FORTHCOMING ‘FLORE DES MASCAREIGNES’ ORCHIDACEAE ACCOUNTS
Authors: Hermans Johan , Cribb Phillip 
Published: June 2021

In preparation for the forthcoming orchid accounts of the Flore des Mascareignes lectotypifications are made for Angraecum cadetii, A. cornigerum, A. corrugatum, A. costatum, A. eburneum, A. mauritianum, A, patens, A. pingue, A. tenuifolium, Benthamia erinacea, B. perfecundum, Bulbophyllum commersonii, B. compressum, B. conicum, B. cordemoyi, B. densum, B. pusillum, B. variegatum, Cynorkis arnottioides, C. calcarata, C. calcaripotens, C. cordemoyi, C. falcata, C. fastigiata, C. flexuosatis, C. graminea, C. lilacina, C. nervilabris, C. paradoxa, C. pleiadea, C. purpurascens, C. reticulate, C. squamosa, C. trilinguis, C. variegata, Disperis cordata, Gastrorchis villosa, Habenaria arachnoides, H. lancifolia, H. praealta, H. undulata, Platylepis densiflora, P. margartifera, P. occlusa, Oeceoclades analavelensis and O. pulchra. Neotypifications are made for Angraecum tenuifolium, Benthamia spiraloides, Cynorkis coccinelloides and C. constellata. Clarification is provided of the taxonomy of Angraecum crassifolium, A. tenellum, Benthamia erinacea, Bulbophyllum densum, B. elliotii, B. incurvum, B. pendulum, Cheirostylis boryi, C. gymnochiloides, C. nuda, Cynorkis calcarata, C. coccinelloides, C. falcata, C. flexuosatis, C. squamosa, Habenaria sigillum, Oeceoclades analavelensis, Platylepis densiflora, P. margaritifera and P. occulta. New combinations are made for Benthamia spiraloides, Bulbophyllum elliotii var. latibracteatum, Cheirostylis boryi, Cynorkis aristei and C. flexuosatis.
Key words/Palabras clave: Mauritius, new combinations, nuevas combinaciones, new synonyms, nuevos sinónimos, Reunion, Rodrigues, typification, tipificación
Reducing power requirement of LPWA networks via machine learning
Authors: Rajab Husam , Ebrahim Mussa , Cinkler Tibor 
Published: June 2021

AbstractRecently, one of the most common needs of people are to be connected to the Internet anytime, anywhere, anyhow. The Internet of Things is a materialized paradigm in which everyday objects are implemented with Internet connectivity, enabling them to collect and interchange information. As energy is expected to be more expensive, the energy supply is often not available for IoT devices, the low power wide area networks attempt to be the solution to this problem. LoRaWAN provides radio coverage over long distances by enhancing the reach of the base stations via adapting transmission rates, transmission power, modulation, duty cycles, etc. This paper aims to decrease the power consumption using machine learning and deep neural network by applying support vector regression and deep neural network algorithms, which can support to extend the battery lifetime.
Heat radiation effects on insulating materials used in buildings
Authors: Hajdu Flóra , Lászlo Gabriella , Kuti Rajmund 
Published: June 2021

Abstract
In recent years, in order to increase the energy efficiency of older buildings in Hungary, several tenders have supported the modernization of the thermal insulation. Various thermal insulation materials have been installed on walls, on slab and on floor. Unfortunately there are cases where thermal insulation materials are not installed in accordance with the construction permit or the manufacturer’s instructions, which poses a serious danger in case of a fire. During the research the effects of heat on the behavior of Expanded PolyStyrene, a thermal insulation material often used in Hungary is examined. Laboratory tests and computer simulations were carried out, which are presented in detail in this paper. The aim of the research is to contribute to increase the fire safety of buildings.
The impact of social interaction on the leftover space
Authors: Wu Mengyang , Bachmann Bálint 
Published: June 2021

Abstract
With the rapid economic development, the original layout structure and spatial functions of the city have been affected. The purpose of this paper is to stimulate the potential and vitality of space through social interaction based on the analysis of activity behavior and traffic travel. Through communication in the existing leftover space, a living community with the purpose of spatial emotional connection is established or reconstructed. The social habits of residents have also undergone many adjustments and reorganizations. In this way, the degree of connection between people and space is deepened, to guide the public to actively participate in the adjustment of the characteristics of leftover space and space optimization, broaden the application boundary of space.
Habitat and Distribution Modeling of Prehistoric Hippos (Hippopotamus sivalensis spp.) During Pleistocene in Java Island
Authors: Andriwibowo Andriwibowo , Basukriadi Adi , Nurdin Erwin 
Published: June 2021

Currently, there are only 2 extant species of hippos including common (Hippopotamus amphibius) and pygmy hippos (Choeropsis liberiensis) . But in prehistoric times, there were several species. During Pleistocene these species were known to migrate to Java Island from Asian Continent and the species was Hippopotamus sivalensis spp. In this regard, this study aimed to model the habitat of H. sivalensis spp., ecology, and biodiversity of Hippopotamus sivalensis spp. based on the fossil record. The model was developed based on the Principal Component Analysis (PCA) method using the R statistical package. The results showed that there were 7 populations of H. sivalensis spp. that lived at various altitudes with an average of 177 m above sea level (95% CI : 123-232 m). According to PCA, there were at least 2 separate populations of H. sivalensis spp. One population occupies the forest while another occupies a habitat close to the coast. Currently the habitat for H. sivalensis spp. already changed. Based on habitat modeling, H. sivalensis spp. inhabit streams with submerged aquatic plants and shrubs and trees growing along river banks.
Penerapan Manajemen Perpustakaan dalam Meningkatkan Mutu Layanan di Perpustakaan MTs Al Ibrohimi Manyar Kabupaten Gresik
Authors: Alimi Thoriq , Achmad Achmad , Rochmah Ainur , Fahmi Muhammad 
Published: June 2021

Penelitian ini bertujuan untuk mendeskripsikan penerapan manajemen perpustakaan, menjelaskan kendala-kendala yang dihadapi serta mendiskripsikan solusi implementasi manajemen perpustakaan di MTs Al Ibrohimi Manyar Gresik Tahun 2019. Jenis penelitian kualitatif, Teknik pengumpulan data yang dilakukan dalam penelitian ini menggunakan 1) metode wawancara, wawancara dilakukan kepada beberapa sumber seperti kepala sekolah, guru, petugas perpustakaan dan siswa. 2) metode observasi dengan mengamati keadaan fisik perpustakaan baik peralatan dan perlengkapannya. 3) Metode Dokumen digunakan untuk mengumpulkan data arsip dan administrasi perpustakaan sekolah. Keabsahan data penelitian menggunakan triangulasi sumber dan teknik, keabsahan data tersebut digunakan untuk menguji data-data yang terkumpul. Hasil pembahasan implementasi manajemen perpustakaan di MTs Al Ibrohimi Manyar Gresik yang dilaksanakan belum sesuai dengan fungsi manajemen. mulai dari Perencanaan yang tidak diperbarui, pengorganisasian yang sangat kurang, pengelolaan perpustakaan yang kurang terkelola dengan baik, dan pengawasan yang sangat kurang. Kendala-kendala dalam penerapan fungsi manajemen dalam pengelolaan perpustakaan di perpustakaan MTs Al Ibrohimi Manyar Gresik meliputi: 1) Tidak Adanya Kepemimpinan Manajemen Perpustakaan Sekolah, 2) Kurangnya Sumberdaya Manusia dan pustakawanan yang profesional, 3) Koleksi Buku Yang Kurang Lengkap dan Kurang Diperbarui, 4) Kurangnya Pengunjung Perpustakaan. Usaha yang dilakukan untuk mengatasi kendala yang dihadapi dalam pelaksanaan manajemen perpustakaan meliputi: 1) Kepala sekolah dapat merekrut atau memilih guru untuk ditugaskan menjadi kepala perpustakaan. 2) pustakawan di perpustakaan MTs Al Ibrohimi Manyar Gresik, harus memiliki tenaga professional dibidang perpustakaan khususnya penerapan fungsi manajemen perpustakaan dalam pengelolaan perpustakaan. 3). mengajukan penambahan koleksi kepada kepala sekolah, sekolah juga mengadakan kerjasama dengan pihak terkait misalnya dengan penerbit dan mengimbuu kepada siswa, guru atau karyawan untuk memberikan sumbangan buku atau menitipkan buku-buku pribadinya untuk disimpan di perpustakaan. 4) memperbaiki Etika Layanan Perpustakaan dan Layanan Sepenuh Hati.
Kata Kunci: Penerapan, Manajemen Perpustakaan, Mutu Layanan ni
Etos Kerja dalam Budaya Organisasi di Kantor Kementerian Agama Kabupaten Gresik
Authors: Faizah Indah Nur , Lestari Linda Lisma , Hidayat Syahrul , Mustofa Ali 
Published: June 2021

ABSTRAK
Salah satu keberhasilan suatu organisasi adalah terwujudnya sasaran, tujuan, visi dan misi organisasi sesuai dengan perencanaan strategi organisasi. Kinerja yang baik akan terlihat pada hasil yang berkualitas. Budaya organisasi yang sesuai dan etos kerja yang baik akan sangat membantu dalam meningkatkan kualitas kinerja menjadi lebih baik. Penelitian ini dilaksanakan pada pegawai di Pendidikan Agama Islam (PAIS) dengan tujuan untuk mengetahui pendorong etos kerja pegawai serta budaya organisasi tanpa kehadiran pemimpin tetap. Metode yang digunakan dalam penelitian ini adalah metode kualitatif deskriptif. Hasil dari penelitian ini adalah meskipun pada seksi PAIS tidak memiliki pimpinan tetap, namun pelayanan dapat berjalan dengan baik tanpa ada hambatan. Etos kerja dan budaya organisasi menjadi salah satu pendorong dalam meningkatkan kualitas kinerja pegawai. Etos kerja dalam seksi Pendidikan Agama Islam Kemenag Kabupaten Gresik ini adalah bekerja secara maksimal, melaksanakan tugas dan tanggung jawabnya sebagai pekerja yang mampu memberikan kontribusi serta melakukan pekerjaan dengan sepenuh hati dan menjauhi tindakan tercela. Faktor yang mempengaruhi etos kerja di PAIS diantaranya ialah adanya budaya organisasi. Pada seksi Pendidikan Agama Islam (PAIS) berpijak pada lima nilai budaya kerja yang ada di kementerian agama, yaitu (1)Integritas, (2)Profesionalitas, (3)Inovasi, (4) Tanggung jawab, (5)Keteladanan.
Kata Kunci : Etos Kerja, Budaya Organisasi

ABSTRACT
One of the successes of an organization is the realization of the goals, objectives, vision and mission of the organization in accordance with the organization's strategic planning. Good performance will be seen in quality results. An appropriate organizational culture and good work ethic will greatly help in improving the quality of performance for the better. This research was conducted on employees at Islamic Religious Education (PAIS) with the aim of knowing the drivers of employee work ethics and organizational culture without the presence of permanent leaders. The method used in this research is descriptive qualitative method. The result of this research is that although the PAIS section does not have permanent leadership, the service can run well without any obstacles. Work ethic and organizational culture are one of the drivers in improving the quality of employee performance. The work ethic in the Islamic Religious Education section of the Ministry of Religion of Gresik Regency is to work optimally, carry out their duties and responsibilities as workers who are able to contribute and do work wholeheartedly and avoid despicable actions. The factors that influence work ethic at PAIS include the presence of organizational culture. The Islamic Religious Education (PAIS) section is based on five cultural values ​​in the ministry of religion, namely (1) Integrity, (2) Professionalism, (3) Innovation, (4) Responsibility, (5) Exemplary.
Keywords: Work Ethic, Organizational Culture
Optimalisasi Emis dalam Proses Data Base Pendidikan Diniyah dan Pondok Pesantren di Kementerin Agama Kabupaten Bangkalan
Authors: Rahmania Savira , Yakin Agus Ainul , Aisy Elvira Rohadatul 
Published: June 2021

Abstract: Education Management Information System (EMIS) is an education management information system to support planning and policy making in Islamic-based education programs. EMIS is a program that also provides real data to support policy makers. Technology and information as data collection bases have a very important role in supporting the achievement of educational goals. With the existence of EMIS, it is hoped that the incoming data can be more accurate and continuously updated so that it can be used as a basis for decision making. This study aims to determine the optimization of EMIS in the process of data base for diniyah education and Islamic boarding schools in the Ministry of Religion, Bangkalan Regency. As EMIS is an education database, it is hoped that the incoming data will be more accurate and updated to make it easier to find information. However, the Diniyah education and Islamic boarding schools in the Ministry of Religion, Bangkalan Emis Regency have not been able to be used optimally. One of these factors is that there are still many human resources who do not fully understand how to operate an EMIS, so that there are still many institutions that have not filled in the existing data on EMIS. The method used by the researcher is descriptive qualitative method, while the data collection technique uses interviews, observation and documentation.
Keywords: EMIS, data dase, Islamic boarding school early education.
Esophageal Involvement and Gastroesophageal Reflux Disease in Systemic Sclerosis: A Tertiary Center Experience
Authors: BACAKSIZ Ferhat , ÖZTÜRK Ömer , ARI Derya , TENLİK İlyas , GÖKBULUT Volkan , ERGÜN Yakup , ÖZDERİN Yasemin , KAYAÇETİN Ertuğrul 
Published: June 2021

Aim: Esophagus is the most frequently involved gastrointestinal segment in systemic sclerosis (SS). Gastroesophageal reflux, which occurs with the motility disorder caused by esophageal involvement, has an important place in the course of the disease due to many local and systemic complications. In this study, we investigated the demographic features, endoscopic, manometric, and 24-hour pH monitoring findings of patients with SS.
Materials and Methods: Twenty-six patients with SS who presented with dysphagia or heartburn complaints were identified. Patients' files, endoscopic, manometric, and 24-hour ph monitoring findings of the esophagus were examined.
Results: All of the patients were symptomatic, 96.1% were women. 46.1% of them applied with the complaint of heartburn and 53.9% with the complaint of dysphagia. The frequency of esophagitis was found to be significantly higher (p = 0.005). Pathological reflux was detected in 90% of the patients who underwent 24-hour pH monitoring and it was significantly higher (p = 0.013).
Conclusion: Esophageal involvement is a hallmark manifestation of SS and typically occurs secondary to heartburn and dysphagia.In our society, the incidence of GERD and GERD-related complications is high in SS patients with esophageal symptoms. It is important to refer these patients to experienced gastroenterology centers to be evaluated primarily by endoscopic and then other diagnostic methods.