bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of graft outcome in renal transplant recipients with antibody-mediated rejection
Authors: Parmaksız Ergün , Meşe Meral , Yadigar Serap , Bahat Kübra Aydın 
Published: September 2021

Abstract. Active and chronic antibody-mediated rejection (ABMR) is a common cause of graft failure. Prognostic markers of this complication are not well defined. We aimed to find out the demographic, histopathological and clinical characteristics of transplant recipients who developed ABMR and evaluate the impact of these features, and anti-rejection treatment modalities on graft survival.
Methods. Thirty-two patients who developed ABMR (22 male; mean age 40.59±12.52 years) were included in this study. Data were evaluated retrospectively and graft survival was analyzed. All transplant biopsies were evaluated according to Banff's 2013 classification.
Results. Among the 32 cases, 26 were transplanted from living donors. Mean serum creatinine at the time of biopsy was 1.99 ±0.09 mg/dL. Proteinuria was 1566.06±353.92 mg/day at the time of biopsy. The need for hemodialysis was significantly related with initial creatinine (p = 0.003); creatinine after three months (p < 0.001) and final creatinine (p < 0.001) as well as initial proteinuria (p = 0.005); proteinuria after three months (p < 0.001) and final proteinuria (p < 0.001). 6 cases showed diffuse C4d positivity, 26 cases showed focal c4d positivity. Five of 6 patients with diffuse C4d staining in renal biopsy were hemodialyzed at first and third months despite anti-rejection therapy (p=0.029 and 0.041, respectively).
Mean survival time was 1654.67±220.40 (95% CI 1222.68-2086.66) days for focal staining C4d cases and 366.16±36.44 (95% CI 294.73-437.60) days for diffuse staining C4d cases. The difference was statistically significant (p=0.012). Two of the patients died, 15 experienced graft loss and 17 survived with functioning grafts. Mean survival time between anti-rejection treatment modalities showed no statistical significance (p=0.15)
Conclusions. Serum creatinine, proteinuria at the time of biopsy, diffuse peritubular C4d staining were significantly associated with graft survival. Early diagnosis is important to improve success in the treatment of ABMR and graft survival
Retrospective Study of Real-World Treatment Patterns and Outcomes in Advanced/Metastatic Renal Cell Carcinoma Patients Receiving Lenvatinib/Everolimus after Heavy Pretreatment
Authors: Vogelzang Nicholas J. , Monnette Alisha M. , Wang Yunfei , Wan Yin , Robert Nicholas J. , Tannir Nizar M. 
Published: September 2021

BACKGROUND: Lenvatinib with everolimus (“Len/Eve”) is approved for advanced/metastatic RCC following one antiangiogenic therapy. OBJECTIVE: This study evaluated patient characteristics, treatment patterns and overall survival (OS) with second-line or later (2L+) Len/Eve for advanced/metastatic RCC. METHODS: A retrospective observational study was conducted using electronic health records. Adult patients who initiated 2L+ Len/Eve for advanced/metastatic RCC from May 13, 2016 to July 31, 2019 were included. Patient characteristics and treatment patterns were assessed across the overall population and by post-immuno-oncology (IO) and post-tyrosine kinase inhibitors (TKI) groups. OS was estimated from Len/Eve initiation (i.e., index date) using Kaplan-Meier. RESULTS: Among the study population ( n = 152), 44.1%received 2L/3L Len/Eve and median number of prior therapies was 3 (range:1–8). Median age was 63.2 years, 78.9%were Caucasian, 73.7%were male, and 56.6%had ECOG performance status 0/1. At initial diagnosis, 65.8%had stage IV disease. At index, 53.3%had an International Metastatic RCC Database Consortium risk score of intermediate/poor, 15.1%favorable, and 31.6%missing score. Sixty-five (42.8%) received IO-based regimens and 49.3%received TKIs directly before index. Median OS from index was 13.9 (95%CI: 9.5–16.5) months and 2L/3L and 4L+ were 12.1 (95%CI: 8.4–17.0) and 14.8 (95%CI: 8.9–22.5) months, respectively. Median OS for Len/Eve post-IO and post-TKI were 13.9 (95%CI: 8.4–21.3) and 14.8 (95%CI: 7.8–16.5) months, respectively. Conclusion: This study suggested that 2L+ Len/Eve has clinical effectiveness for advanced/metastatic RCC in a US community oncology setting. Future studies are needed to confirm the association of improved survival with 2L+ Len/Eve.
PENGARUH PENDEKATAN GUIDED INKUIRI TERHADAP PRESTASI BELAJAR SEJARAH SISWA SMAN W PANCOR
Authors: Mahrup Abdul Rasyad 
Published: September 2021

diterima: 03 Mei 2013; dikembalikan untuk direvisi: 13 Mei 2013; disetujui: 22 Mei 2013Abstrak:Penelitian ini bertujuan untuk menemukan pengaruh pendekatan guided inkuiri dengan memberikan tugas menulis karya ilmiah terhadap prestasi belajar sejarah siswa kelas X SMA NW Pancor tahun pembelajaran 2012/2013. Penelitian ini tergolong penelitian kuantitatif dan metode penelitiannya menggunakan penelitian eksperimen. Rancangan eksperimen menggunakan rancangan pre-test/post-test. Populasi penelitian adalah siswa kelas X SMA NW Pancor tahun pembelajaran 2012/2013. Karena populasi penelitian tergolong kecil, dengan demikian penelitian ini termasuk penelitian populasi. Instrumen pengumpulan data menggunakan tes. Metode pengumpulan data menggunakan tes, observasi, dan dokumentasi, sedangkan terkait analisis data menggunakan analisis statistik uji-t. Pengujian persyaratan analisis dilakukan dengan metode Liliefors untuk uji normalitas dan metode Barlett untuk uji homogenitas varians. Hasil penelitian disimpulkan penggunaan pendekatan guide inquiri dengan memberikan tugas menulis karya ilmiah berpengaruh terhadap prestasi belajar sejarah siswa kelas X SMA NW Pancor tahun pembelajaran 2012/2013. Hal ini dibuktikan dari hasil penghitungan menggunakan rumus t tes dihasilkan t hitung 5.08 dan t table pada taraf signifikansi 5 % didapatkan batas angka penolakan hipotesis dengan db = 48 adalah 2.08, sehingga t hitung > t tabel (5,08 > 2,08).Kata Kunci: pendekatan guided inkuiri, karya ilmiah, prestasi belajarAbstract: This study aimed to find the effect of guided inquiry approach by giving the task of scientific paper writing on the academicÂ achievement of history subject on NW Pancor high school class X in 2012 to 2013. This study was classified as quantitative research and the research methode used was experiment. The experimental design used a pre-test/post-test design. The population of the study was the X graders of NW Pancor high school year 2012/2013. Because the population of the study was relatively small, thus the research was included in the population study. The instrument of data collecting was test. Test, observation, and documentation were the methods of data collececting, while related to the data analysis, the t-test statistical analysis was used. Requirement test was conducted by using Liliefors method for variance normality test and Barlett method for variance homogeniety test. The result of the study concluded that the use of guided inquiry approach by giving scientific paper writing infuenced the academic achievement of history subject of NW Pancor high school class X students in the year 2012/2013. It was proven by the result of calculation using t test, in which t was 5.08 and t table was in 5% significance level, hypothesis rejection limit in db=48 was 2.08, so the t count > t table ( ( 5.08 > 2.08 ). Keywords: guided inquiry approach, scientific paper, academic achievement
EVALUASI STRATEGI PEMANFAATAN SIARAN PENDIDIKAN INTERAKTIF BAHASA INDONESIA UNTUK SMP DI TV EDUKASI
Authors: Widawati Widawati 
Published: September 2021

Abstrak:Tujuan penelitian ini untuk mengevaluasi strategi pemanfaatan Siaran Pendidikan Interatif di TV Edukasi pada mata pelajaran Bahasa Indonesia di SMP. Siaran Pendidikan Interaktif adalah siaran yang khusus membahas soal-soal prediksi UN yang ditayangkan TV Edukasi dan juga direlay TVRI Nasional setiap hari menjelang UN pada pukul 13.00-14.00 WIB. Siaran pendidikan Interaktif merupakan upaya pemerintah dalam mempersiapkan para siswa dalam menghadapi Ujian Nasional di seluruh tanah air. Penelitian ini dilaksanakan di tiga SMP dengan data penelitian dikumpulkan melalu Focus Group Disccusion terhadap 11 orang guru Bahasa Indonesia dan observasi. Hasil penelitian ini menunjukkan bahwa strategi pemanfaatan secara langsung Siaran Pendidikan Interatif mata pelajaran Bahasa Indonesia belum optimal dilakukan karena adanya berbagai kendala seperti keterbatasan perangkat siaran dan kurangnya sosialisasi program.Kata kunci: evaluasi, siaran pendidikan interatif TV Edukasi, strategi pemanfaatan secara langsung.Â Abstract:The purpose of this research is to evaluate the direct utilization strategy of Interactive Education Broadcast (Siaran Pendidikan Interaktif) of Bahasa Indonesia for Junior High School Students at Educational TV (TV Edukasi). The Education Broadcast is designed and devoted to broadcast National Exam predictions at TV Edukasi which is also relayed every day by National Television, TVRI at 13:00 to 14:00 pm. Siaran Pendidikan Interaktif is a government attempt to prepare the students to face the National Exam. This research was conducted in three junior high schools with research data collected through Focus Group Disccusion towards 11 (eleven) Indonesian teachers and 11 (eleven) times of observation. The results of this study shows that the direct utilization strategy of Interactive Education Broadcast of Bahasa Indonesia for Junior High School Students at TV Edukasi is not yet optimal due to various constraints such as limited broadcasts devices and lack of socializationKeywords: evaluation, direct utilization strategy, siaran pendidikan interaktif, TV Edukasi
Prevalence of gastric ulcer syndrome in horses with different exercise intensity
Authors: Stefanyk O. , Slivinska L. 
Published: September 2021

Gastric ulcers or equine gastric ulcer syndrome (EGUS) is a common pathology in horses of different breeds. The objective of our research work was to investigate and determine the prevalence and severity of equine gastric ulcer syndrome (EGUS) in population of n = 28 riding horses with periods of physical activity and training intensity. Two breeds were presented in this study: English Thoroughbred (n = 15) and Ukrainian riding horse (n = 13). Horses were two age groups 3–7 and 8–16 years, including 17 mares and 11 geldings. Gastric endoscopy was performed as a diagnostic tool using a 3m video endoscope. Mucosal defects was evaluated using grading system proposed by (Equine Gastric Ulcer Council 0–4 grading system) ranging from 0 (normal mucosa with no lesions) to 4 (diffuse ulceration of mucosa with deep lesions). The study was conducted in two periods. Each period is related to different workload with mixed intensity in exercise during training program. The results of gastroscopic examination of the stomach indicate the prevalence of EGUS in 35.7 % during the first stage in horses with mild training. The severity of mucosal defect during this period which were related to grade 1 was shown in 10.7 % of horses, 2 – 21.4 %, 3 – 10.7 % and 4 – 0 %. Difference in results was found in the presence and severity of gastric ulcers between two periods in this study. During period of intermediate training the prevalence of EGUS was 46.4 % with severity of mucosal defect grade 1 presented in 14.2 % of affected horses, 2 – 28.5 %, 3 – 14.2 % and 4 – 3.5 %. Ulcerations on squamous gastric mucosa was diagnosed more often during each period (35.7 – 50 %) compare to glandular (7.1 – 10.7 %). The study confirms association between training intensity and gastric ulceration in two breed of horses. The prevalence and severity is dependent of the training intensity.
Biotechnology of families’ strength influence on the processes of sucrose inversion, dehydration and accumulation of monosaccharides
Authors: Bezpalyi I. F. 
Published: September 2021

The purpose of the work is an experimental substantiation of biotechnological processes that ensure the maturation of honey during the processing of nectar by bees. During the whole period (7–9 days) of nectar treatment by bees there is a simultaneous partial dehydration of the liquid and biochemical transformations, among which the hydrolysis of sucrose and the accumulation of monosaccharides have the most significant effect on the quality of the mature product. In all series of experiments, the maturity of processed honey in the beehive at the water limit of less than 20 % occurs after 5–6 days of treatment by bees. The mature product in terms of water content remains open in almost completely filled cells for another 3–5 days, slightly reducing the water content from 19.78–20.07 % up to 16.40–18.38 %. Dynamic changes in the ratio of monosaccharides and sucrose in the process of nectar processing by bees, starting from the honey stomach during gathering from flowers to sealing in honeycomb cells have been detected. At the honey stomach-cell stage, a small amount of sucrose is hydrolyzed during the incomplete first day of processing and, as a rule, 0.48–4.11 % of monosaccharides calculated relative to the dry weight of the product are added. Sucrose inversion is more intense during the next 5–6 days, when a total of 12.94–31.42 % of splitted sugars are added, depending on their initial number and strength of families. The main processes of conversion of nectar into honey by bees are characterized by the advance of the reduction of water content in comparison with the splitting of sucrose and the accumulation of monosaccharides. According to the water content (less than 20 %), honey becomes suitable for pumping 3–5 days before it is sealed in the cells. The influence of the mass of bees of different families on the intensity of sucrose inversion in the cells and the accumulation of monosaccharides in the product has been experimentally proved. The maturity of honey in the ratio of sugars in the beehives of strong families is better than in weak ones.
TEKNIK SUBSTRING WEIGHTING UNTUK KONVERSI MATA KULIAH
Authors: Madsu Yosi Malatta 
Published: September 2021

[Id]
Konversi mata kuliah adalah suatu pekerjaan yang mungkin membutuhkan waktu lebih bila dilakukan secara manual. Pemindahan data transkrip menjadi data digital membutuhkan cara untuk memproses data tersebut lebih lanjut menjadi hasil konversi yang diinginkan. Salah satu cara untuk memproses data transkrip berbagai program studi dari berbagai perguruan tinggi menjadi hasil konversi yang diinginkan adalah dengan menggunakan Teknik Substring Weighting. Substring Weighting adalah implementasi text mining dari tiap-tiap nama mata kuliah asal yang dimanfaatkan dengan mekanisme pembobotan dan ranking untuk mencari hasil konversi terhadap mata kuliah tujuan. Hasil implementasi teknik ini dapat mempercepat proses administrasi konversi, 80% kasus konversi dapat dilakukan kurang dari 5 menit.
Kata kunci :
substring, weighting, mining, konversi mata kuliah.
[En]
A manual academic transcript conversion will take a lot of time to be done. But when the digital process is involved, we need a method to process a whole academic transcript data to help to make good conversion results. Substring Weighting is a method to convert any academic transcript to specific academic transcript using text mining to every subject name. Each substring may be weighted and sorted to match criterias of each destination subject. By these technique, at least 80% of conversion processes are done in less than 5 minutes.
Keywords :
substring, weighting, mining, transcript conversion.
SEGMENTASI KOLEKSI DATA UNTUK MENDUKUNG PERFORMANSI SISTEM
Authors: Aradea Aradea , Supriana Iping , Surendro Kridanto 
Published: September 2021

[Id]
Pengelolaan koleksi data merupakan hal yang sangat kritis, apalagi jika melibatkan volume data yang sangat besar, karena hal ini akan berpengaruh terhadap performansi sistem secara menyeluruh. Suatu rancangan strategi khusus dibutuhkan bagi penyediaan performansi sistem, sehingga sistem mampu mengerjakan tugas-tugasnya sesuai dengan indikator sistem. Salah satu inini. Makalah ini akan menguraikan salah satu persoalan yang berhubungan dengan application tuning, terutama beberapa hal yang berhubungan dengan kebutuhan penggunaan segmentasi atau partisi untuk mengelompokan koleksi data yang besar. Pembahasan diawali dengan latar belakang, dilanjutkan dengan teori-teori terkait, kemudian mendefinisikan ilustrasi kasus, analisis dan pembahasan kasus, proses implementasi dan pengujian, serta kesimpulan dan pekerjaan kedepan
[EN]
Management of data collection is one of critical matter, event if involving a large volume of data because its will affect to all system performance. a particular strategic planning is needed to provision system performance, then the system able to do its jobs suitable with system indicator. one of very general indicator that can be used to assess system performance is speed. Basically, speed connected with tuning technique, and at the current time, there are many types, both theory or methodology that can be used in tuning technique. This paper will depict one problem that related to tuning application, especially some item that related with the requirement of using segmentation or partition to grouping large data collection. Depiction started with a background, then continued with related theories, case illustration, analyze and case description, implementation process, testing, conclusion and future works.
PENGGUNAAN METODE PUSAT GRAVITAS DALAM PENENTUAN LOKASIGUDANG TERHADAP JARAK MEMINIMALKAN PENGIRIMAN TRANSPORTASI PADA PT. XYZ
Authors: Firdaus M. Riky , Putra Peri Anggara 
Published: September 2021

Abstrak
XYZ adalah perusahaan yang memproduksi ban untuk semua kendaraan besar maupun kendaraan kecil. Kegiatan penelitian pada PT. XYZ bertujuan untuk mengetahui titik gudang yang baru dengan memperhatikan setiap letak atau tempat konsumen berada, hal ini dilakukan agar penempatan gudang baru dapat lebih fleksibel dan terjangkau dari setiap konsumen. Peletakan gudang baru ini juga akan berpengaruh terhadap ongkos biaya setiap pengiriman menjadi lebih murah dan mempersingkat pengiriman. Metode analisis yang digunakan adalah dengan menggunakan metode center of gravity. Hasil perhitungan dengan menggunakan metode center of gravity didapat lokasi gudang baru dengan titik kordinat X= 1.62, Y= 4.16, yang berlokasi di Bukanagara, dengan lokasi gudang baru ini maka akan meminimalkan jarak tempuh dan biaya transportasi setiap pengiriman barang.
Kata kunci: Metode center of gravity, Biaya transportasi.
PERANCANGAN ULANG MODEL RANTAI PASOK PASAR TRADISIONAL DIGITAL
Authors: Artha Kusuma Putu Giri , Pambudi Hardian Kokoh , Yulianti Femi 
Published: September 2021

Pasar tradisional memiliki peranan yang sangat penting bagi masyarakat maupun pemerintah. Kondisi pandemik Covid-19 yang terjadi saat ini memaksa adanya perancangan ulang terhadap rantai pasok yang tahan terhadap perubahan kondisi lingkungan yang menuntut para pihak berinteraksi secara terbatas. Terbatasnya interakasi ini telah menyebabkan terjadinya penurunan laju perekonomian pada triwulan I-2020 dibandingkan triwulan I-2019. Pertumbuhan ekonomi pada triwulan I-2020 adalah sebesar 2,97% (y.o.y), sedangkan pada triwulan I-2019 adalah sebesar 5,07%. Perancangan ulang dilakukan dengan melakukan analisis dan sintesis literatur terkait. Model SCOR dengan mempertimbangkan atribut strategis yaitu Keandalan, Responsif, Agility, Biaya dan Aset menjadi acuan utama pada penelitian ini. Perancangan ulang difokuskan pada sisi distribusi yang menghasilkan dua aktor baru pada rantai pasok pasar tradisional yaitu penyedia layanan pengiriman online dan penyedia layanan pembayaran online. Penyedia layanan pengiriman online mendukung kelancaran arus barang pada sisi distribusi rantai pasok pasar tradisional. Penyedia layanan pembayaran online mendukung kelancaran arus uang, dan transparansi transaski antar aktor. Penyesuaian proses bisnis antar aktor pada sisi distribusi rantai pasok pasar tradisional juga dilakukan pada penelitian ini.
IMPLEMENTASI ALGORITMA FAST FOURIER TRANSFORM PADA MONITOR GETARAN UNTUK ANALISIS KESEHATAN JEMBATAN
Authors: Fatah Ahmad 
Published: September 2021

Jembatan merupakan bagian yang penting dalam suatu sistem jaringan jalan, karena pengaruhnya yang signifikan bila jembatan itu runtuh atau tidak berfungsi dengan baik, maka keruntuhan jembatan akan mengganggu kelancaran transportasi orang dan barang. Sistem monitor dikembangkan untuk dapat mengetahui kondisi struktur jembatan agar dapat mengantisipasi kegagalan struktur. Dimana dari hasil monitor ini akan dihasilkan data ferekuensi alami, tekanan beban dan lendutan. Data akselerasi Sumbu x,y,dan z akan diolah dengan algoritma Fast Fourier Transform (FFT), kemudian data ferekuensi yang telah diolah akan menghasilkan ferekuensi alami jembatan. Dari hasil penelitian menunjukkan bahwa monitoring getaran jembatan dapat ditampilkan dengan data akselerasi sumbu X, Y dan Z maupun FFT. Dengan beban 6 KG didapat akselerasi Sumbu x = 1.29, Y = 0.73 dan Z = 13.39, Ferkunesi Dasar X = 1.82, Y = 1.03 dan Z = 18.93. Untuk parameter lendutan dengan akurasi 99.66%, dengan beban 6Kg didapat Rata-rata error sebesar 11 mm (millimeter) dengan rata-rata persentase error sebesar 0.0396%. untuk parameter Teakann berat dengan akurasi 99,534% , dengan beban 6 Kg didapat Rata-rata persentasi error sebesar 0.1821 Kg dengan persentase error tertinggi sebesar 0.4566%. Kesimpulan yang didapatkan dari hasil penilitian bahwa setiap sensor untuk mengitung parameter kesehatan pada purwarupa Jembatan dengan bentang 65cm dari aspek getaran tergolong pada nilai kondisi baik dengan nilai getaran 1,82 Hz. Ditinjau dari aspek lendutandengan beban muatan 6KG, jembatan tidak baik, karena memiliki rata-rata lendutan adalah 10 mm atau 1 cm, dengan batas maksimal 0,65 cm.
SISTEM INFORMASI MONITORING DAN LAPORAN PROYEK FIBERISASI DI PT. EKSPANINDO PRIMA MULTIMEDIA
Authors: Kusumah Perdana Bagja , Eosina Puspa , Jaenudin Jejen 
Published: September 2021

PT.Ekspanindo Prima Multimedia merupakan perusahaan yang bergerak di bidang telekomunikasi yang memberikan layanan terpadu di dalam proyek pembangunan jaringan fiber optik di beberapa kota di Indonesia. Untuk mengontrol proyek fiberisasi yang dilakukan memerlukan volume data pekerjaan proyek, mulai dari perencanaan, pelaksanaan, dan akhir proyek. Dalam proses tiga tahapan tersebut data pekerjaan dapat diterapkan ke dalam sistem dengan menggunakan metode pengembangan sistem model linear sequential terdiri dari analisis, desain, implementasi, dan pengujian. Penerapan ilmu sistem informasi pada proses pengolahan data proyek fiberisasi ini adalah (1) menganalisis dan membuat perancangan sistem informasi dengan metode linear sequential yang menghasilkan analisis kebutuhan fungsional, analisis pengguna, dan desain sistem menggunakan UML Diagram, dan di implementasikan menggunakan bahasa komputer. (2) sistem yang di bangun menampilkan informasi berupa daftar volume data perencanaan, pelaksanaan, akhir proyek, dan data selisih untuk dapat memantau pekerjaan proyek fiberisasi yang dibutuhkan oleh PT.Ekspanindo Prima Multimedia.