bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performance Evaluation of Abandoned Fly Ash Deposit Improved by Dynamic Compaction for Construction of Highway Embankment
Authors: Zheng Xiao , Zhang Qian-Qing , Wang Shu-jian , Wu Shi-qian , Cui Wei 
Published: November 2021

Abstract
In developing countries such as India and China, large amounts of unused fly ash were landfilled into ash deposit on uncultivated land. With an increase in traffic engineering, these ash ponds could probably be reclaimed to construct heavyweight engineering. This requires sufficient strength of foundation to ensure the safety of engineering located on the fly ash deposit. In this paper, a successful utilization of dynamic compaction on a fly ash pond is reported based on embankment engineering of a national highway. Field and lab tests of the ponded ash before and after the compaction are carried out, showing calibration of construction parameters and increased strength of the compacted ash. It has been found that the drop numbers should be determined mainly by the calculated total of penetrated settlement, though the increase in the penetrated settlement is less than 5 cm. The limited value of the bearing capacity of the post-compacted ash can be increased by about 300 %, which meets the design requirement of strength. Results also show that the improved thickness and bearing capacity at the side compaction locations are lower than those of the central position because of the boundary effect. Considering the slope stability of embankment under traffic loading, at least two main compaction locations should be set outside the boundary of the slope toe in the design process.
Minimizing Iridium Oxide Electrodes for High Visual Acuity Subretinal Stimulation
Authors: Damle Samir , Carleton Maya , Kapogianis Theodoros , Arya Shaurya , Cavichini-Corderio Melina , Freeman William R. , Lo Yu-Hwa , Oesch Nicholas W. 
Published: November 2021

AbstractVision loss from diseases of the outer retina, such as age-related macular degeneration, is among the leading causes of irreversible blindness in the world today. The goal of retinal prosthetics is to replace the photo-sensing function of photoreceptors lost in these diseases with optoelectronic hardware to electrically stimulate patterns of retinal activity corresponding to vision. To enable high-resolution retinal prosthetics, the scale of stimulating electrodes must be significantly decreased from current designs; however, this reduces the amount of stimulating current that can be delivered. The efficacy of subretinal stimulation at electrode sizes suitable for high visual acuity retinal prosthesis are not well understood, particularly within the safe charge injection limits of electrode materials. Here, we measure retinal ganglion cell (RGC) responses in a mouse model of blindness to evaluate the stimulation efficacy of 10, 20, and 30 μm diameter iridium oxide electrodes within the electrode charge injection limits, focusing on measures of charge threshold and dynamic range. Stimulation thresholds were lower for smaller electrodes, but larger electrodes could elicit a greater dynamic range of spikes and recruited more ganglion cells within charge injection limits. These findings suggest a practical lower limit for planar electrode size and indicate strategies for maximizing stimulation thresholds and dynamic range.
A tiszaeszlári vérvád és a nyíregyházi per az élclapok hasábjain
Authors: Tamás Ágnes 
Published: November 2021

Az elemzés forrása, időintervalluma
A nyíregyházi per végítéletének kimondása előtt jegyezte le az egyik elemzésre kerülő bécsi vicclap, a Figaro szerzője, hogy „a magyar glóbusz uralja most az egész világtörténelmet”, utalva arra, hogy Európa-szerte nagy érdeklődést váltott ki a tiszaeszlári vérvád és az azt tárgyaló nyíregyházi per. A forrásbázis nagyobb részét képező magyarországi élclapok a per eseményeit pontosan követték, a megelőző hét történéseire reagáltak humoros-gúnyos cikkeikkel és karikatúrákkal, így ha egymás után vizsgálnánk a lapszámokat, a per és a hozzá kapcsolódó helyszínek rajzolódnának ki előttünk – egy pártpolitikától sem független görbe tükrön keresztül. Elöljáróban megállapíthatjuk, hogy az izraelita Ágai Adolf által szerkesztett, az antiszemita hangulat ellen fellépő, kormánypárti Borsszem Jankón kívül a másik két elemzett magyar ellenzéki lap – a Bolond Istókés az Üstökös – nyíltan antiszemita nézeteket hangoztatott, míg a Karl Sitter által életre hívott liberális Figaro magán a tényen gúnyolódott, hogy az eljárás a zsidók ellen egyáltalán elkezdődhetett. A bécsi élclap nem követte napról napra az eseményeket, de több számában is foglalkozott a vérváddal, majd üdvözölte a felmentő ítéletet.
Precise Locating of the Great 1897 Shillong Plateau Earthquake Using Teleseismic and Regional Seismic Phase Data
Authors: Subedi Shiba , Hetényi György 
Published: November 2021

Abstract
Pinched between the Eastern Himalaya and the Indo-Burman ranges, the Shillong Plateau represents a zone of distributed deformation with numerous visible and buried active faults. In 1897, a great (magnitude 8+) earthquake occurred in the area, and although a subsurface rupture plane has been proposed geodetically, its epicenter remained uncertain. We gathered original arrival time data of seismic waves from this early-instrumental era and combined them with modern, 3D velocity models to constrain the origin time and epicenter of this event, including uncertainties. Our results show that the earthquake has taken place in the northwest part of the plateau, at the junction of the short, surface-rupturing Chedrang fault and the buried Oldham fault (26.0°N, 90.7°E). This latter fault has been proposed earlier based on geodetic data and is long enough to host a great earthquake. Rupture has most likely propagated eastward. Stress change from the 1897 earthquake may have ultimately triggered the 1930 M 7.1 Dhubri earthquake, along a fault connecting the Shillong Plateau with the Himalaya.
Mean and True Positions of Planets as Described in Gaṇitagannaḍi
Authors: Shylaja B S , Javagal Seetharam 
Published: November 2021

The unpublished seventeenth-century Kannaḍa-language mathematical work Gaṇitagannaḍi is transmitted in a single palm-leaf manuscript. It was composed by Śaṅkaranārāyaṇa Jōisaru of Śṛṅgeri and is a karaṇa text cast as a commentary on the Vārṣikatantrasaṅgraha by Viddaṇācārya. Gaṇitagannaḍi's unique procedures for calculations wer introduced in an earlier paper in volume 8 (2020) of this journal. In the present paper the procedures for calculations of the mean and true positions of planets are described.
Use of Instagram as a Promotion Media of the Faculty Library at Gadjah Mada University
Authors: Karunia Leila 
Published: November 2021

Background of the study: Libraries use social media to promote libraries for users, one of which is Instagram. Gadjah Mada University Library (UGM) and several faculty libraries have used Instagram as a promotional media, but not all are up to date.
Purpose: The purposes of this study are to identify the way the faculty library promotes through Instagram and analyze the motivation factors and obstacles faced in promoting the library through Instagram.
Method: This study was conducted at the faculty library at UGM used a thick description with a qualitative approach. Data collection techniques used are in-depth interviews, observation and literature study. This study discusses the use of Instagram as a library promotion media from librarians and staff who manage the library's Instagram.
Findings: The results of the study show that: First, seven of the eighteen library libraries at UGM were promoted through Instagram. The way the faculty library promoting on Instagram is through posting content such as documenting events, library services, promoting events, and e-resources. Second, the motivation factor of the faculty library at UGM to use Instagram as a promotion media is to adapt to the generation of users and social media used by users. The obstacle faced by most faculty libraries in using Instagram as a library promotion media is the limitations of Human Resources (HR).
Conclusion: The use of Instagram as a promotion media of faculty libraries at UGM is still not up to date. The majority of faculty libraries haven't used Instagram to promote the library. Seven faculty libraries have used Instagram but are not the same in up to date.
Differences in information source preferences by students during pre and post PSBB covid-19 pandemic
Authors: Darmawan Mochamad , Handika Cahyo , Pratama M. Didan , Al Maulana M. Aflah 
Published: November 2021

Background of Study: The increasingly rapid and massive spread of the COVID-19 virus to various countries, has made the Indonesian Government implement a Large-Scale Social Restriction (PSBB) policy in order to stop the spread of the virus. This policy makes various activities, such as services in libraries, must be closed. This of course makes library users, such as students switch to using electronic information sources. Furthermore, the Government decided to start a new era habit or called the "New Normal" by living adapting to the spread of the virus.
Purpose: This research was conducted in order to review the preferences of information sources used by students after the PSBB policy.
Method. The research method used is a quantitative approach, with a descriptive type. The target population of this research are students from Surabaya. Data collection was carried out by means of a survey using a questionnaire. Then processed using the SPSS 18.0 application
Analysis. The analysis uses theory in the literature.
Results: The results showed that most of the students chose electronic information sources as their main preference. This is indicated by the results of research showing that information retrieval machines have become a popular choice both in the pre and post PSBB periods. However, comparative figures show that there are differences in several sources of information in the two periods.
Conclusion: Since the PSBB, most students have experienced changes in their preferences for information sources.
Utization of Instagram as a Library’s Digital Marketing
Authors: Masyithah Deby Claudia 
Published: November 2021

Background of the study: Instagram is one of the most popular social media today, so Instagram is very effective as a media for library promotion. Through Instagram, users who like social media can view photos of library collections or view library images. Through Instagram, librarians can easily disseminate information, offer library services, promote libraries or communicate directly with users.
Purpose: The purpose of this study will be to analyze how the use and influence of Instagram as a digital marketing library facility
Method: This research uses qualitative method. Informants from this study were UGM S-1 students and UIN Sunan Kalijaga who are still actively studying and have an Instagram account.
Findings: The results of this study are that there are still many students who do not know of the existence of a library Instagram account either at UGM or UIN Sunan Kalijaga. Students who know and follow Instagram library accounts do not always access information from their Instagram account. They prefer to come directly to the library or visit the official library website if you want to find out information about the library. This is because the content on the library's Instagram account is unattractive and does not match what is needed by students.
Conclusion: Students visit the library not because they see it from the library's Instagram account, because the content uploaded from the two Instagram accounts is dominated by photos of activities held in the library not about collections or facilities in the library.
Volar DRUJ Instability After Midshaft Both-Bone Forearm Fracture in a Toddler
Authors: Stocker-Downing T. Hunter , Biolzi Francesco , O'Brien Frederick P. , Shaw K. Aaron 
Published: November 2021

Case:
A 2.5-year-old male child presented to the clinic for evaluation of left wrist popping. Ten months earlier, he sustained a closed left both-bone forearm fracture (BBFF) treated with reduction and casting. His clinical course was complicated by redisplacement requiring secondary manipulation and casting before osseous union. His parents reported wrist popping with active motion in the setting of a 20° apex volar malunion of the midshaft radius. He has been treated with observation and monitoring of deformity remodeling.

Conclusion:
Distal radioulnar joint instability is a potential complication of malunited BBFF, even in a pediatric population. Residual deformity, especially in the radius, should prompt clinical follow-ups after osseous union to assess functional recovery and deformity remodeling.
The 18-cm Thoracic-Height Threshold and Pulmonary Function in Non-Neuromuscular Early-Onset Scoliosis
Authors: Johnston Charles E. , Karol Lori A. , Thornberg David , Jo Chanhee , Eamara Pablo 
Published: November 2021

Background:
Thoracic spine height is cited as a crucial outcome measure in the treatment of early-onset scoliosis (EOS) because of its reported relationship to pulmonary function tests (PFTs). An 18-cm threshold has been proposed, although this single parameter might be overly simplistic for cases of different etiologies and deformity magnitude. We aimed to reevaluate pulmonary function in patients undergoing corrective surgery, assessing the role of residual scoliosis as well as spine elongation

Methods:
Patients undergoing EOS correction with a minimum of 5 years of follow-up since initial treatment were evaluated. Standard spirometry (forced vital capacity [FVC], forced expiratory volume in 1 second [FEV1]) was correlated to deformity magnitude and T1-T12 height. Patients were compared by age at first surgery (<5 or ≥5 years), final thoracic height (≤18 or >18 cm), and percentage of predicted pulmonary function (<60% or ≥60%).

Results:
Twenty-nine patients (15 congenital, 11 syndromic, and 3 idiopathic cases) were tested at a mean of 8.5 years following initial surgery. Twenty-two patients (mean initial age, 4.8 years) had growth-sparing instrumentation, and 7 patients (age, 5.1 years) had definitive fusion performed. Age at initial surgery was not associated with a difference in PFT results at the time of follow-up, and both age groups had ominously low percentages of predicted pulmonary-function volumes (50% to 55%). Only 18 of the 29 patients achieved a T1-T12 height of >18 cm. Those with a thoracic height of ≤18 cm had similar percentage-of-predicted spirometry results at the time of follow-up as those with greater thoracic height, possibly because of increased deformity correction. Only 14 of 29 patients had spirometry of ≥60% of predicted volume at the time of follow-up. These 14 had slightly smaller curves and slightly greater T1-T12 heights but significantly better spirometry results than the 15 subjects with <60% of predicted volume. For those with a T1-T12 height of ≤18 cm, the residual Cobb angle negatively correlated with spirometry results. In those with a final T1-T12 height of >18 cm, spirometry did correlate with thoracic height, especially when residual deformity was ≥60°.

Conclusions:
Regardless of thoracic height of ≤18 or >18 cm, with residual curves of >50o, pulmonary function was ominously low in fully half of the patients, raising doubt about the value of this threshold as an EOS outcome parameter.

Level of Evidence:
Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
An Immuno-Histochemical Assessment of Ki67, P53 Over-Expression in Helicobacter Pylori Positive Gastritis.
Authors: Tawfeeq Karam Turath , Hamdi Elaf Abdulwahhab , Al-azzo Nadwa Subhi 
Published: November 2021

Abstract
Background and Objective: Helicobacter pylori infection of the stomach is a common disease and the resulting changes from it are numerous and deserve to be in the focus of researchers' attention. The aim of this study is to assess the expression of mutant P53 protein and Ki-67 markers in patients with gastritis secondary to Helicobacter pylori.Methods: Thirty samples with positive Helicobacter pylori gastritis were included in a retrospective study in Mosul / Iraq. The histological parameters were assessed using the Sydney system, then the expression of Ki67 and P53 expression were studied by immunohistochemical methods. The significance level was appointed at (0.05).Results: Ki67 and P53 expression were found in 83.3% of the total cases. The study results show that 92% of positive Ki67, P53 cases had chronic inflammatory cell infiltration, polymorph nuclear cells infiltration, and atrophy. Whereas 96% of positive Ki67 cases had no metaplasia, 92% of the positive P53 cases had no metaplasia. The results also showed that only 16% of the positive Ki67 cases had dysplastic changes, and 24 % of the positive cases of P53 cases were showed dysplasia. moreover, whenever P53 was negative; there is neither metaplasia nor dysplasia in the tissue, this does not apply to Ki67 negative cases.Conclusions: Ki67, P53 expressions increase with chronicity of Helicobacter pylori-positive gastritis, P53 expression is amplified when atrophy is present in these samples
­­Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians
Authors: Ni Qi , Chen Xiang , Zhang Ping , Yang Lin , Lu Yulan , Xiao Feifan , Wu Bingbing , Wang Huijun , Zhou Wenhao , Dong Xinran 
Published: November 2021

Abstract
Background

Cystic fibrosis (CF) is a common, life-threatening genetic disease in Caucasians but rarely reported in Chinese population. The prevalence and population-specific genetic spectrum of CF in China needs to be systematically estimated and compared with Caucasians.
Materials & Methods

We reviewed 30,951 exome-sequencing samples, including 20,909 children samples and 10,042 parent samples, from Chinese Children's Rare Disease Genetic Testing Clinical Collaboration System (CCGT). After the in-lab filtration process, 477 candidate variants of CFTR gene were left and 56 variants were manually curated as pathogenic/likely-pathogenic (P/LP). These P/LP variants were adopted to estimate CF prevalence in three methods: the carrier frequency method, the permutation-combinations method and the Bayesian framework method. Allele frequencies of the 477 CFTR variants were compared with non-Finland European (NFE) and East Asian (EAS) from gnomAD database. To investigate the haplotype structure difference of CFTR, another 2,067 whole-genome-sequencing samples from CCGT and 195 NFE from 1000 genome project were analyzed by Shapeit4 software.
Result

With the 56 manually curated P/LP variants in CFTR gene, the estimated Chinese CF prevalence is approximately 1/106,400. Only 21 (37.5%) of the 56 variants were included in Caucasian specific CF screening panels, resulting in significantly under-estimation of CF prevalence in our children cohort (1/114,659 vs. 1/1,121,017, P=9e-27) and parents’ cohort (1/96,968 vs. 1/797,207, P=1e-10). The allele frequencies of six pathogenic variants (G970D, D979A, M469V, G622D, L88X, c.1766+5G>T) were significantly higher in our cohorts compared with gnomAD-NFE population (all P-value<0.1). Haplotype analysis showed more haplotype diversity in Chinese compared to Caucasians. In addition, G970D and F508del were founder mutation of Chinese and Caucasians with two SNPs (rs213950-rs1042077) identified as related genotype in exon region.
Conclusions

Chinese population showed significantly different genetic spectrum pattern in CFTR gene compared with Caucasian population, and thus a Chinese-specific CF screening panel is needed.
Clinicopathological Characteristics and Immunohistochemistry of Intracranial Hemangiopericytoma: Case Report and Literature Review
Authors: Yang Shikun , Lian Junbo , Huang Wenxuan , Liu Yang , Huo Shuangjie , Dong Liru 
Published: November 2021

Abstract
BackgroundHemangiopericytoma was first named as a soft tissue tumor in 1942. It is a group of tumors composed of short spindle cells with pericyte growth. It is rare in clinical practice and accounts for 0.4 of all tumors originating in the central nervous system 0.4%, with a high degree of recurrence and the potential for metastasis outside the central nervous system.Case presentationWe report 4 patients, including 1 male and 3 females. All patients had headache, dizziness, and fatigue. The first and fourth patients showed acute exacerbation, paroxysmal limb twitching, flexion of both upper limbs, straightening of both lower limbs, unconsciousness, unresponsiveness, and upper eyeballs. Turning and closing of the teeth, 1 out of 2 patients was accompanied by a tongue bite. All 4 patients underwent imaging examinations. Considering the possibility of meningiomas and gliomas, all 4 patients underwent surgical resection and were followed up many times after the operation. The first case was followed up for 68 months and passed away due to recurrence without treatment. The second case was followed up for 50 months and relapsed at 42 months after the operation. It relapsed again 18 months after the operation and passed away with multiple metastases throughout the body; the third patient died in time The 4 patients were followed up for 32 months and 9 months respectively, and there is no recurrence at present.ConclusionsMeningeal HPC is a rare clinical tumor. 4 cases were followed up for 9-68 months, 2 cases recurred after surgery, and 1 case had multiple metastases throughout the body. It is not easy to distinguish HPC from meningioma on imaging. The diagnosis still depends on pathological examination, combined with the combined diagnosis of STAT6, CD34 and ALDHIA1 immunohistochemical markers, which can effectively improve the diagnosis and differential diagnosis of the disease. Because HPC is prone to recurrence and metastasis, Long-term follow-up and timely follow-up are still needed after operation.
Catechol-O-Methyltransferase Activity in Individuals with Substance Use Disorders: A Case Control Study
Authors: Azevedo Jacinto Nuno Costa , Carvalho Cláudia , Serrão Maria Paula , Coelho Rui , Figueiredo-Braga Margarida , Coelho Maria Augusta Vieira 
Published: November 2021

Abstract
Background

Impulsivity and substance use disorders (SUD) can be related to the same environmental factors. In this study, we intended to evaluate the dopaminergic function in imprisoned SUD offenders through the determination of s-COMT activity.
Methods

The study included 46 male individuals from a Portuguese penal institution. The participants were assessed through a battery of standardised instruments: Psychopathy Checklist-Revised (PCL-R), Barratt Impulsivity Scale Version 11 (BIS-11), and the European version of the Addiction Severity Index (EuropASI). s-COMT erythrocyte activity was evaluated.
Results

Overall, 73.9% (n=34) of the individuals had Antisocial Personality Disorder (ASPD) and 58.7% (n=27) presented SUDs. We evidenced, for the first time, that, in SUD individuals, s-COMT activity is correlated with the severity of drug dependence (EuropASI) (p<0.05), and with BIS-11 factors self-control (p<0.0001) and non-planning (p=0.002).
Conclusions

This study opens new perspectives regarding the pharmacological intervention on drug dependence through the interference on dopamine pathways.