bluuebunny/crossref_metadata_2025_split huggingface dataset:
Establishing seeded tall fescue with covers and drip irrigation methods
Authors: Bach Alex P. , Bremer Dale J. , Lavis Cathie C. , Keeley Steven J. 
Published: December 2021

AbstractThe use of covers may improve the establishment of seeded turfgrass but their use in combination with drip irrigation techniques has not been evaluated. In this study, repeated twice in the spring of 2020 near Manhattan, KS, we investigated the effects of two cover types and three irrigation methods on the establishment of seeded tall fescue turfgrass [Schedonorus arundinaceus (Schreb.) Dumort.]. Turfgrass cover types included (a) polyester mesh, (b) a straw blanket, and (c) no cover as a control. Irrigation treatments were (a) subsurface drip irrigation, (b) aboveground drip irrigation, and (c) overhead sprinkler irrigation (control). Measurements of green cover, ground and drone‐based normalized difference vegetation indices, and visual turfgrass quality ratings indicated that establishment was improved with both cover types compared with uncovered plots, in the order polyester > straw > uncovered in both trials, but polyester and straw became similar over time. The soil surface temperature averaged higher in polyester (14 °C) than in straw (9.5 °C) and uncovered (8.6 °C) plots during the first 12 d after seeding when the covers were installed. The results indicate that covers improved the spring establishment of seeded, cool‐season turfgrass in a fine‐textured soil and in a U.S. transition zone climate by mitigating low temperature extremes and reducing erosion during rainfall. Establishment was similar between drip (subsurface and aboveground) and sprinkler‐irrigated treatments, but the use of protective covers is recommended when establishing turfgrass from seed.
Fluoxetine‐induced hepatic lipid accumulation is mediated by prostaglandin endoperoxide synthase 1 and is linked to elevated 15‐deoxy‐Δ12,14PGJ2
Authors: Ayyash Ahmed , Holloway Alison C. 
Published: December 2021

AbstractMajor depressive disorder and other neuropsychiatric disorders are often managed with long‐term use of antidepressant medication. Fluoxetine, an SSRI antidepressant, is widely used as a first‐line treatment for neuropsychiatric disorders. However, fluoxetine has also been shown to increase the risk of metabolic diseases such as non‐alcoholic fatty liver disease. Fluoxetine has been shown to increase hepatic lipid accumulation in vivo and in vitro. In addition, fluoxetine has been shown to alter the production of prostaglandins which have also been implicated in the development of non‐alcoholic fatty liver disease. The goal of this study was to assess the effect of fluoxetine exposure on the prostaglandin biosynthetic pathway and lipid accumulation in a hepatic cell line (H4‐II‐E‐C3 cells). Fluoxetine treatment increased mRNA expression of prostaglandin biosynthetic enzymes (Ptgs1, Ptgs2, and Ptgds), PPAR gamma (Pparg), and PPAR gamma downstream targets involved in fatty acid uptake (Cd36, Fatp2, and Fatp5) as well as production of 15‐deoxy‐Δ12,14PGJ2 a PPAR gamma ligand. The effects of fluoxetine to induce lipid accumulation were attenuated with a PTGS1 specific inhibitor (SC‐560), whereas inhibition of PTGS2 had no effect. Moreover, SC‐560 attenuated 15‐deoxy‐Δ12,14PGJ2 production and expression of PPAR gamma downstream target genes. Taken together these results suggest that fluoxetine‐induced lipid abnormalities appear to be mediated via PTGS1 and its downstream product 15d‐PGJ2 and suggest a novel therapeutic target to prevent some of the adverse effects of fluoxetine treatment.
3D Sub‐Diffraction Printing by Multicolor Photoinhibition Lithography: From Optics to Chemistry
Authors: He Minfei , Zhang Zhimin , Cao Chun , Zhou Guozun , Kuang Cuifang , Liu Xu 
Published: December 2021

AbstractPhotoinhibition lithography (PIL) is a nanoscale fabrication technique that uses multicolor visible light to enable the printing of arbitrary 3D structures beyond the diffraction limit. Photoinhibition allows the control and confinement of the exposed region for photoinitiation during the photolithographic process, thus improving the resolution of existing lithographic techniques, such as direct laser writing. Because PIL enables super‐resolution 3D printing, it has a multitude of applications. In this review, practical applications of PIL in the areas of photonics, data storage, and biotechnology are highlighted; in addition, its unique features are revealed. The theory and recent advances in PIL for sub‐diffraction printing and high‐throughput fabrication are also discussed. Besides, challenges and tentative solutions are discussed with the hope of providing a preliminary roadmap for technological breakthroughs in PIL to enable developments of resolution and throughput.
The impact of self‐service versus interpersonal contact on customer–brand relationship in the time of frontline technology infusion
Authors: Lee Heekyung , Yi Youjae 
Published: December 2021

AbstractIn response to the widespread utilization of contact‐free technology in service interactions, this study compares the tradeoffs between self‐service technology and interpersonal contact by demonstrating the mediating effects of social comfort and perceived empathy, which eventually impact the overall brand evaluation. Specifically, this study reveals social comfort as an underlying mechanism behind digital customers' preference for self‐service technology over interpersonal contact. Also, it recognizes that the relational cost of self‐service technology is its lack of empathy with customer needs and that the benefit of human contact is a fulfillment of the consumer need for caring. This study further reveals the moderating role of the service provider's persuasive intent that can increase the benefit and reduce the drawback of interpersonal contact.
Self‐Report versus Clinician Examination in Early Parkinson's Disease
Authors: Zolfaghari Sheida , Thomann Alessandra E. , Lewandowski Natalia , Trundell Dylan , Lipsmeier Florian , Pagano Gennaro , Taylor Kirsten I. , Postuma Ronald B. 
Published: December 2021

AbstractBackgroundEvaluating the discrepancies between patient‐reported measures and clinician examination has implications for formulating individual treatment regimens.ObjectiveThis study investigated the association between health outcomes and level of self‐reported motor‐related function impairment relative to clinician‐examined motor signs.MethodsRecently diagnosed PD patients were evaluated using the Parkinson's Progression Marker Initiative (PPMI, N = 420) and the PASADENA phase II clinical trial (N = 316). We calculated the average normalized difference between each participant's part II and III MDS‐UPDRS (Movement Disorder Society Unified Parkinson's Disease Rating Scale) scores. Individuals with score differences <25th or >75th percentiles were labeled as low‐ and high‐self‐reporters, respectively (those between ranges were labeled intermediate‐self‐reporters). We compared a wide range of clinical/biomarker readouts among these three groups, using Kruskal–Wallis nonparametric and Pearson's χ2 tests. Spearman's correlations were tested for associations between MDS‐UPDRS subscales.ResultsIn both cohorts, high‐self‐reporters reported the largest impairment/symptom experience for most motor and nonmotor patient‐reported variables. By contrast, these high‐self‐reporters were similar to or less impaired on clinician‐examined and biomarker measures. Patient‐reported nonmotor symptoms on MDS‐UPDRS part IB showed the strongest positive correlation with self‐reported motor‐related impairment (PPMI rs = 0.54, PASADENA rs = 0.52). This correlation was numerically stronger than the part II and clinician‐examined MDS‐UPDRS part III correlation (PPMI rs = 0.38, PASADENA rs = 0.28).ConclusionSelf‐reported motor‐related impairments reflect not only motor signs/symptoms but also other self‐reported nonmotor measures. This may indicate (1) a direct impact of nonmotor symptoms on motor‐related functioning and/or (2) the existence of general response tendencies in how patients self‐rate symptoms. Our findings suggest further investigation into the suitability of MDS‐UPDRS II to assess motor‐related impairments. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society
STRONGkids nutrition screening tool in pediatrics: An analysis of cutoff points in Brazil
Authors: Castro Joice da Silva , Santos Carolina Araújo dos , Rosa Carla de Oliveira Barbosa , Firmino Heloísa Helena , Ribeiro Andréia Queiroz 
Published: December 2021

AbstractBackgroundStudies have indicated the Screening Tool for Risk on Nutritional Status and Growth (STRONGkids) as a method of pediatric nutrition screening with good validity in the hospital setting. However, we need to analyze whether the cutoff values originally proposed are suitable for use in Brazil.MethodsA cross‐sectional study was performed in patients admitted to the pediatric ward of a public hospital. STRONGkids was used to assess nutrition risk (low risk, 0 points; moderate risk, 1–3 points; and high risk, 4–5 points). The indexes weight/height or body mass index/age were used to indicate acute malnutrition, and length or height/age was used to indicate chronic malnutrition. Receiver operating characteristic curves were constructed and the areas under the curve were calculated, with respective 95% confidence intervals, to assess the ability of STRONGkids to predict malnutrition and longer hospital stay.ResultsThe study included 599 patients, with a median age of 2.6 years. The frequency of nutrition risk (medium or high) was 83.6%. In comparison with anthropometric indexes, STRONGkids was the only scoring system with the discriminatory capacity to identify patients with longer hospital stays. The comparative analysis of the means of hospital stay according to STRONGkids showed that patients with a score equal to 3 behaved similarly to those classified as high nutrition risk (4–5 points).ConclusionsConsidering the best cutoff point to predict prolonged hospitalization, STRONGkids used in Brazil should consider patients with 3 points as having high nutrition risk, as well those scoring 4 and 5.
Effect of tailored, daily feedback with lifestyle self‐monitoring on weight loss: The SMARTER randomized clinical trial
Authors: Burke Lora E. , Sereika Susan M. , Parmanto Bambang , Bizhanova Zhadyra , Kariuki Jacob K. , Cheng Jessica , Beatrice Britney , Loar India , Pulantara I Wayan , Wang Yuhan , Cedillo Maribel , Conroy Molly B 
Published: December 2021

AbstractObjectiveThis study aimed to test the efficacy of self‐monitoring and feedback (SM+FB) versus SM without FB (SM) in a behavioral weight‐loss intervention at 6 months.MethodsThis was a randomized clinical trial. Eligibility criteria included the following: ≥18 years of age, BMI ≥ 27 and ≤43, smartphone user, and ability to engage in moderate physical activity. All participants received a 90‐minute 1:1 counseling session, a Fitbit Charge 2, and a digital scale for SM. SM+FB participants were provided access to a customized smartphone application that provided three daily FB messages. The primary outcome was percentage of weight change from 0 to 6 months.ResultsThe sample (N = 502) was 45 (SD 14.4) years old, BMI was 33.7 (SD 4.00) kg/m2, 79.5% of participants were female (n = 399), and 84.3% were White (n = 423). At 6 months, there was 85.86% retention and a significant percentage of weight change in both groups (SM+FB: −3.16%, 95% CI: −3.85% to −2.47%, p < 0.0001; SM: −3.20%, 95% CI: −3.86% to −2.54%, p < 0.0001) but no significant between‐group mean difference (−0.04%, 95% CI: −0.99% to 0.91%, p = 0.940). A ≥5% weight loss was achieved by 31.9% of the SM+FB group and 28.3% of the SM group.ConclusionsThere was no significant between‐group difference in weight loss at 6 months.
Restoring Oat Nanoparticles Mediated Brain Memory Function of Mice Fed Alcohol by Sorting Inflammatory Dectin‐1 Complex Into Microglial Exosomes
Authors: Xu Fangyi , Mu Jingyao , Teng Yun , Zhang Xiangcheng , Sundaram Kumaran , Sriwastva Mukesh K. , Kumar Anil , Lei Chao , Zhang Lifeng , Liu Qiaohong M. , Yan Jun , McClain Craig J. , Merchant Michael L. , Zhang Huang‐Ge 
Published: December 2021

AbstractMicroglia modulate pro‐inflammatory and neurotoxic activities. Edible plant‐derived factors improve brain function. Current knowledge of the molecular interactions between edible plant‐derived factors and the microglial cell is limited. Here an alcohol‐induced chronic brain inflammation model is used to identify that the microglial cell is the novel target of oat nanoparticles (oatN). Oral administration of oatN inhibits brain inflammation and improves brain memory function of mice that are fed alcohol. Mechanistically, ethanol activates dectin‐1 mediated inflammatory pathway. OatN is taken up by microglial cells via β‐glucan mediated binding to microglial hippocalcin (HPCA) whereas oatN digalactosyldiacylglycerol (DGDG) prevents assess of oatN β‐glucan to dectin‐1. Subsequently endocytosed β‐glucan/HPCA is recruited in an endosomal recycling compartment (ERC) via interaction with Rab11a. This complex then sequesters the dectin‐1 in the ERC in an oatN β‐glucan dependent manner and alters the location of dectin‐1 from Golgi to early endosomes and lysosomes and increases exportation of dectin‐1 into exosomes in an Rab11a dependent manner. Collectively, these cascading actions lead to preventing the activation of the alcoholic induced brain inflammation signing pathway(s). This coordinated assembling of the HPCA/Rab11a/dectin‐1 complex by oral administration of oatN may contribute to the prevention of brain inflammation.
Development of Flexible and Thin Films from Underutilized Indian Finger Millet (Eleusine coracana) Starch
Authors: Gautam Naina , Garg Sangeeta , Yadav Shashikant 
Published: December 2021

AbstractThe present work explores the possibilities of developing finger millet starch (FMS) films with sorbitol (DS) at various concentrations. Therefore, starch is isolated from three diverse underutilized Indian finger millet varieties (VL‐149, VL‐371, and VL‐376). The results reveal that amylose content, moisture content, and ash content of FMS are observed in the range of 31.12 ± 0.37–33.87 ± 0.64%, 8.47 ± 0.75–9.87 ± 0.37%, and 0.33 ± 0.18–0.78 ± 0.91%, respectively. In addition, the solubility and swelling index of the FMS is found to be in the range of 1.5 ± 0.34–1.7 ± 0.11% and 9.98 ± 0.31–11.25 ± 0.64% at 60 °C. This work investigates the effects of varying concentrations (20%, 30%, 40%, and 50%) of sorbitol (DS) as a plasticizer on the FMS film's main functional properties, thermal, and structural. The results present that elongation at break‐point is increased while film density, swelling index, water vapor permeability, tensile strength, and solubility are reduced upon the addition of DS. Scanning electron microscope images show that the FMS film surfaces with DS are more homogeneous and continuous without air bubbles than those without DS. Thermal gravimetric analysis and differential scanning calorimetry results indicate that the thermal stability of the FMS film improves with DS.
IsSalmonella entericashared between wildlife and cattle in cattle farming areas? An 11‐year retrospective study in Tokachi district, Hokkaido, Japan
Authors: Yamaguchi Emi , Fujii Kei , Kayano Mitsunori , Sakurai Yoshie , Nakatani Atsuko , Sasaki Motoki , Hertl Julia A. , Grohn Yrjo T. 
Published: December 2021

AbstractBackgroundSalmonella entericain cattle has long been problematic and suspected to be transmitted by wildlife in Tokachi, Hokkaido, a major cattle farming area in Japan. Understanding the role of wildlife inS. entericatransmission would be helpful for developing control strategies of bovine salmonellosis.ObjectivesWe aimed to elucidate the possibility ofS. entericatransmission between sympatric wildlife, including raccoons and crows and cattle, in Tokachi from 2008 to 2018 by analysingS. entericadetection records, and the genetic relatedness of serotypes shared between wildlife and cattle.MethodsS. entericadetection records were based on the results of a field survey and existing cattle records at relevant organisations, including clinical reports, a monitoring survey and quarantine for introduced calves at growing farms and public calving farms.S. entericawas identified by polymerase chain reaction assay and serotyped by agglutination assay. The detection records were organised chronologically to investigate whether common serotypes in wildlife and cattle were detected in the same year. The isolates corresponding to detection records were assessed for their genetic patterns by pulsed‐field gel electrophoresis.ResultsThe prevalence ofS. entericain raccoons and crows was 10.7% (17/159) and 5.7% (55/967), respectively. The following serotypes were detected from both wildlife and cattle: Braenderup, Dublin, Infantis, Mbandaka, Montevideo, 4,[5],12:i:‐ and Typhimurium. Genetically similar isolates forS. Braenderup,S. Dublin,S. Montevideo andS. 4,[5],12:i:‐ were detected from both species in the same year.ConclusionsOur long‐term retrospective observations supported thatS. entericawas shared between wildlife and cattle. Wildlife invasions should be controlled at farms to prevent inter‐species transmission ofS. entericafrom livestock farms.
Duals of Feynman integrals. Part I. Differential equations
Authors: Caron-Huot Simon , Pokraka Andrzej 
Published: December 2021

AbstractWe elucidate the vector space (twisted relative cohomology) that is Poincaré dual to the vector space of Feynman integrals (twisted cohomology) in general spacetime dimension. The pairing between these spaces — an algebraic invariant called the intersection number — extracts integral coefficients for a minimal basis, bypassing the generation of integration-by-parts identities. Dual forms turn out to be much simpler than their Feynman counterparts: they are supported on maximal cuts of various sub-topologies (boundaries). Thus, they provide a systematic approach to generalized unitarity, the reconstruction of amplitudes from on-shell data. In this paper, we introduce the idea of dual forms and study their mathematical structures. As an application, we derive compact differential equations satisfied by arbitrary one-loop integrals in non-integer spacetime dimension. A second paper of this series will detail intersection pairings and their use to extract integral coefficients.
A Weyl-Z2 semimetal from holography
Authors: Ji Xuanting , Liu Yan , Sun Ya-Wen , Zhang Yun-Long 
Published: December 2021

Abstract
We present effective field theories for the weakly coupled Weyl-Z2 semimetal, as well as the holographic realization for the strongly coupled case. In both cases, the anomalous systems have both the chiral anomaly and the Z2 anomaly and possess topological quantum phase transitions from the Weyl-Z2 semimetal phases to partly or fully topological trivial phases. We find that the topological phase transition is characterized by the anomalous transport parameters, i.e. the anomalous Hall conductivity and the Z2 anomalous Hall conductivity. These two parameters are nonzero at the Weyl-Z2 semimetal phase and vanish at the topologically trivial phases. In the holographic case, the different behavior between the two anomalous transport coefficients is discussed. Our work reveals the novel phase structure of strongly interacting Weyl-Z2 semimetal with two pairs of nodes.
A multi-domain ontology on healthy ageing for the characterization of older adults status and behaviour
Authors: Mastropietro Alfonso , Palumbo Filippo , Orte Silvia , Girolami Michele , Furfari Francesco , Baronti Paolo , Candea Ciprian , Roecke Christina , Tarro Lucia , Sykora Martin , Porcelli Simone , Rizzo Giovanna 
Published: December 2021

AbstractAgeing is a multi-factorial physiological process and the development of novel IoT systems, tools and devices, specifically targeted to older people, must be based on a holistic framework built on robust scientific knowledge in different health domains. Furthermore, interoperability must be guaranteed using standardized frameworks or approaches. These aspects still largely lack in the specific literature. The main aim of the paper is to develop a new ontology (the NESTORE ontology) to extend the available ontologies provided by universAAL-IoT (uAAL-IoT). The ontology is based on a multidomain healthy ageing holistic model, structuring well-assessed scientific knowledge, specifically targeted to healthy older adults aged between 65 and 75. The tool is intended to support, and standardize heterogeneous data about ageing in compliance with the uAAL-IoT framework. The NESTORE ontology covers all the relevant concepts to represent 3 significant domains of ageing: (1) Physiological Status and Physical Activity Behaviour; (2) Nutrition; and (3) Cognitive and Mental Status and Social Behaviour. In total, 12 sub-ontologies were modelled with more than 60 classes and sub-classes referenced among them by using more than 100 relations and around 20 enumerations. The proposed ontology increases the uAAL collection by 40%. NESTORE ontology provides innovation both in terms of semantic content and technological approach. The thorough use of this ontology can support the development of a decision support system, to promote healthy ageing, with the capacity to do dynamic multi-scale modelling of user-specific data based on the semantic annotations of users’ profile.
Monitoring one-carbon metabolism by mass spectrometry to assess liver function and disease
Authors: Guerrero Laura , Sangro Bruno , Ambao Verónica , Granero José Ignacio , Ramos-Fernández Antonio , Paradela Alberto , Corrales Fernando J. 
Published: December 2021

Abstract
Precision medicine promises to overcome the constraints of the traditional “one-for-all” healthcare approach through a clear understanding of the molecular features of a disease, allowing for innovative and tailored treatments. State-of-the-art proteomics has the potential to accurately explore the human proteome to identify, quantify, and characterize proteins associated with disease progression. There is a pressing need for informative biomarkers to diagnose liver disease early in its course to prevent severe disease for which no efficient treatment is yet available. Here, we propose the concept of a cellular pathway as a functional biomarker, whose monitorization may inform normal and pathological status. We have developed a standardized targeted selected-reaction monitoring assay to detect and quantify 13 enzymes of one-carbon metabolism (1CM). The assay is compliant with Clinical Proteomics Tumor Analysis Consortium (CPTAC) guidelines and has been included in the protein quantification assays that can be accessed through the assay portal at the CPTAC web page. To test the feasibility of the assay, we conducted a retrospective, proof-of-concept study on a collection of liver samples from healthy controls and from patients with cirrhosis or hepatocellular carcinoma (HCC). Our results indicate a significant reconfiguration of 1CM upon HCC development resulting from a process that can already be identified in cirrhosis. Our findings indicate that the systematic and integrated quantification of 1CM enzymes is a promising cell function-based biomarker for patient stratification, although further experiments with larger cohorts are needed to confirm these findings.