bluuebunny/crossref_metadata_2025_split huggingface dataset:
Singular and combined effects of transcranial infrared laser stimulation and exposure therapy on pathological fear: a randomized clinical trial
Authors: Zaizar Eric D. , Papini Santiago , Gonzalez-Lima F. , Telch Michael J. 
Published: July 2021

AbstractBackgroundPreclinical findings suggest that transcranial infrared laser stimulation (TILS) improves fear extinction learning and cognitive function by enhancing prefrontal cortex (PFC) oxygen metabolism. These findings prompted our investigation of treating pathological fear using this non-invasive stimulation approach either alone to the dorsolateral PFC (dlPFC), or to the ventromedial PFC (vmPFC) in combination with exposure therapy.MethodsVolunteers with pathological fear of either enclosed spaces, contamination, public speaking, or anxiety-related bodily sensations were recruited for this randomized, single-blind, sham-controlled trial with four arms: (a) Exposure + TILS_vmPFC (n = 29), (b) Exposure + sham TILS_vmPFC (n = 29), (c) TILS_dlPFC alone (n = 26), or (d) Sham TILS _dlPFC alone (n = 28). Post-treatment assessments occurred immediately following treatment. Follow-up assessments occurred 2 weeks after treatment.ResultsA total of 112 participants were randomized [age range: 18–63 years; 96 females (85.71%)]. Significant interactions of Group × Time and Group × Context indicated differential treatment effects on retention (i.e. between time-points, averaged across contexts) and on generalization (i.e. between contexts, averaged across time-points), respectively. Among the monotherapies, TILS_dlPFC outperformed SHAM_dlPFC in the initial context, b = −13.44, 95% CI (−25.73 to −1.15), p = 0.03. Among the combined treatments, differences between EX + TILS_vmPFC and EX + SHAM_vmPFC were non-significant across all contrasts.ConclusionsTILS to the dlPFC, one of the PFC regions implicated in emotion regulation, resulted in a context-specific benefit as a monotherapy for reducing fear. Contrary to prediction, TILS to the vmPFC, a region implicated in fear extinction memory consolidation, did not enhance exposure therapy outcome.
Eudocia’s Singing Deacon: Another Programmatic Passage In Late Antique Christian Verse
Authors: Faulkner Andrew 
Published: July 2021

AbstractAmongst the varied literary output of the fifth-century empress Aelia Eudocia is a hexameter paraphrase of the martyrdom of Saints Cyprian and Justina. The opening lines of the poem, which were rediscovered in the second half of the 20th century, describe the conversion of Justina (Justa) to Christianity through the preaching of a deacon named Praulius. Even as Eudocia remains close to her prose model(s), she imposes her own interpretation upon the text through subtle variation and careful choice of poetic vocabulary. In her version, she depicts the preacher Praulius as a Christian counterpart to the traditional singer of hexameter poetry, linked also to her own poetic activity. This description of Praulius’ transformational preaching, prominently placed at the outset of the poem, constitutes another programmatic passage in late antique Christian verse.
A Dissenting Voice: The Clash of Trade and Warfare in Giovanni da Empoli's Account of His Second Voyage to Portuguese Asia
Authors: Salonia Matteo 
Published: July 2021

AbstractGiovanni da Empoli's second voyage to Asia (1510–1514) was eventful and violent, characterised by the emergence of conflicting agendas among different groups of Portuguese. The Florentine merchant's long letter about the voyage is an extraordinary document, and provides insights in three important areas. First, it allows us to fill some of the gaps in the history of the early phases of Portuguese empire building, questioning the extent to which the Crown was pursuing a clear and coherent strategy that included the conquest of Malacca. Second, it problematises further our conception of “the Portuguese” by reporting episodes of Portuguese-on-Portuguese violence and opposing views on the objectives of Portuguese fleets in the Indian Ocean. Finally, Giovanni unequivocally expresses admiration for the international markets of Eastern city-ports and openly criticises the militarist attitude and lawless tactics of the Portuguese viceroy, Alfonso de Albuquerque, thereby inviting us to reconsider the chronology of a “cosmopolitan reaction” among Italian writers visiting South Asia.
‘A large population, famous for their military qualities’: Londoners at war, c. 1000–1200
Authors: Gerrard Daniel 
Published: July 2021

AbstractThe scholarship of high medieval warfare tends not to emphasize the contribution made by urban communities, regarding cities as the passive objects of military campaigning. This article shows that the inhabitants of medieval London, however, had emerged as an organized military community from an early date, and were regarded by contemporaries as unusually disciplined, effective, fighters.
Consuming media, consuming food: investigating concurrent TV viewing and eating using a 7-d time use diary survey
Authors: Alblas Monique C , Mollen Saar , Wennekers Annemarie M , Fransen Marieke L , van den Putte Bas 
Published: July 2021

AbstractObjective:One explanation for the relationship between TV viewing and obesity is that people may (over)eat while watching TV. The current study investigated associations between TV viewing and the time spent on (concurrent) eating in a naturalistic setting among a general population sample.Design:Preregistered secondary data analyses were performed of a diary survey in which respondents reported their time use in 10-min blocks for 7 d.Setting:Concurrent TV viewing and eating was operationalised as all blocks in which TV viewing and eating occurred simultaneously. Furthermore, the TV content respondents watched was coded as food-related (i.e. culinary content) or non-food related.Participants:The sample composed of 2292 adults (58·9 % female) in the Netherlands, aged ≥ 20 years, from all educational levels (18·1 % low, 29·8 % middle and 51·4 % high).Results:More than half of the respondents (51·3 %) reported concurrent TV viewing and eating at least once during the 7-d diary period. The average eating occasion was longer in duration while watching TV (v. without media use), and the total time spent on eating was longer on days of concurrent TV viewing and eating (v. days of eating without media use). The percentage of TV viewing time spent on concurrent eating did not differ between food-related and non-food-related TV content.Conclusions:Eating while watching TV was related to an increased time spent on eating. Even though energy intake was not assessed, these findings from a naturalistic setting provide further evidence that concurrent TV viewing and eating may contribute to overeating.
What drives support for social distancing? Pandemic politics, securitization, and crisis management in Britain
Authors: Karyotis Georgios , Connolly John , Collignon Sofía , Judge Andrew , Makropoulos Iakovos , Rüdig Wolfgang , Skleparis Dimitris 
Published: July 2021

AbstractSupport for social distancing measures was, globally, high at the early stages of the COVID-19 pandemic but increasingly came under pressure. Focusing on the UK, this article provides a rigorous exploration of the drivers of public support for social distancing at their formative stage, via mixed methods. Synthesizing insights from crisis management and securitization theory, thematic analysis is employed to map the main frames promoted by the government and other actors on the nature/severity, blame/responsibility, and appropriate response to the pandemic, which ‘follows the science’. The impact of these on public attitudes is examined via a series of regression analyses, drawing on a representative survey of the UK population (n = 2100). Findings challenge the prevailing understanding that support for measures is driven by personal health considerations, socio-economic circumstances, and political influences. Instead, crisis framing dynamics, which the government is well-positioned to dominate, have the greatest impact on driving public attitudes.
Phased-array antennas using novel PSoC-controlled phase shifters for wireless applications
Authors: Barbadekar Aparna B. , Patil Pradeep M. 
Published: July 2021

AbstractThe paper proposes a system consisting of novel programmable system on chip (PSoC)-controlled phase shifters which in turn guides the beam of an antenna array attached to it. Four antennae forming an array receive individual inputs from the programmable phase shifters (IC 2484). The input to the PSoC-based phase shifter is provided from an optimized 1:4 Wilkinson power divider. The antenna consists of an inverted L-shaped dipole on the front and two mirrored inverted L-shaped dipoles mounted on a rectangular conductive structure on the back which resonates in the ISM/Wi-Fi band (2.40–2.48 GHz). The power divider is designed to provide the feed to the phase shifter using a beamforming network while ensuring good isolation among the ports. The power divider has measured S11, S21, S31, S41, and S51 to be −14, −6.25, −6.31, −6.28, and −6.31 dB, respectively at a frequency of 2.45 GHz. The ingenious controller is designed in-house using a PSoC microcontroller to regulate the control voltage of individual phase shifter IC and generate progressive phase shifts. To validate the calibration of the in-house designed control circuit, the phased array is simulated using $s_p^2$ touchstone file of IC 2484. This designed control circuit exhibits low insertion loss close to −8.5 dB, voltage standing wave ratio of 1.58:1, and reflection coefficient (S11) is −14.36 dB at 2.45 GHz. Low insertion loss variations confirm that the phased-array antenna gives equal amplitude and phase. The beamforming radiation patterns for different scan angles (30, 60, and 90°) for experimental and simulated phased-array antenna are matched accurately showing the accuracy of the control circuit designed. The average experimental and simulated gain is 13.03 and 13.48 dBi respectively. The in-house designed controller overcomes the primary limitations associated with the present electromechanical phased array such as cost weight, size, power consumption, and complexity in design which limits the use of a phased array to military applications only. The current study with novel design and enhanced performance makes the system worthy of the practical use of phased-array antennas for common society at large.
Peat Soil Burning in the Mezzano Lowland (Po Plain, Italy): Triggering Mechanisms and Environmental Consequences
Authors: Natali Claudio , Bianchini Gianluca , Cremonini Stefano , Salani Gian Marco , Vianello Gilmo , Brombin Valentina , Ferrari Mattia , Vittori Antisari Livia 
Published: July 2021

AbstractThe effects of peat burning on organic‐rich agricultural soils of the Mezzano Lowland (NE Italy) were evaluated on soil profiles variously affected by smoldering. Profiles were investigated for pH, electrical conductivity, bulk density, elemental and isotopic composition of distinct carbon (and nitrogen) fractions. The results suggest that the horizons affected by carbon loss lie at depths 10–70 cm, where the highest temperatures are developed. We suggest that the exothermal oxidation of methane (mediated by biological activity) plays a significant role in the triggering mechanism. In the interested soils we estimated a potential loss of Soil Organic Carbon of approximately 110 kg m−2 within the first meter, corresponding to 580 kg CO2 m−3. The released greenhouse gas is coupled with a loss of soil structure and nutrients. Moreover, the process plausibly triggers mobility of metals bound in organometallic complexes. All these consequences negatively affect the environment, the agricultural activities and possibly also health of the local people.
Using Machine Learning to Analyze Physical Causes of Climate Change: A Case Study of U.S. Midwest Extreme Precipitation
Authors: Davenport Frances V. , Diffenbaugh Noah S. 
Published: July 2021

AbstractWhile global warming has generally increased the occurrence of extreme precipitation, the physical mechanisms by which climate change alters regional and local precipitation extremes remain uncertain, with debate about the role of changes in the atmospheric circulation. We use a convolutional neural network (CNN) to analyze large‐scale circulation patterns associated with U.S. Midwest extreme precipitation. The CNN correctly identifies 91% of observed precipitation extremes based on daily sea level pressure and 500‐hPa geopotential height anomalies. There is evidence of increasing frequency of extreme precipitation circulation patterns (EPCPs) over the past two decades, although frequency changes are insignificant over the past four decades. Additionally, we find that moisture transport and precipitation intensity during EPCPs have increased. Our approach, which uses deep learning visualization to understand how the CNN predicts EPCPs, advances machine learning as a tool for providing insight into physical causes of changing extremes, potentially reducing uncertainty in future projections.
The Recent Emergence of Arctic Amplification
Authors: England Mark R. , Eisenman Ian , Lutsko Nicholas J. , Wagner Till J. W. 
Published: July 2021

AbstractArctic Amplification is robustly seen in climate model simulations of future warming and in the paleoclimate record. Here, we focus on the past century of observations. We show that Arctic Amplification is only a recent phenomenon, and that for much of this period the Arctic cooled while the global‐mean temperature rose. To investigate why this occurred, we analyze large ensembles of comprehensive climate model simulations under different forcing scenarios. Our results suggest that the global warming from greenhouse gases was largely offset in the Arctic by regional cooling due to aerosols, with internal climate variability also contributing to Arctic cooling and global warming trends during this period. This suggests that the disruption of Arctic Amplification was due to a combination of factors unique to the 20th century, and that enhanced Arctic warming should be expected to be a consistent feature of climate change over the coming century.
Underwater Sound Levels in the Arctic: Filling Knowledge Gaps
Authors: Halliday William D. 
Published: July 2021

AbstractClimate change is projected to cause the Arctic soundscape to become noisier due to sea ice loss and increased anthropogenic activity. Many studies on underwater sound levels have been conducted in the western North American Arctic and Fram Strait, but the rest of the Arctic is full of geographic gaps. Han et al. (2021, https://doi.org/10.1029/2021gl093097) published a study in Geophysical Research Letters on underwater sound levels in the East Siberian Sea, providing the first estimates of seasonal trends and the natural and anthropogenic drivers of underwater sound levels in this region. This is an excellent first step in filling geographic gaps in the Russian Arctic, and I call on other researchers to continue to fill these geographic gaps throughout the Arctic so that we can set a baseline and study changes to underwater sound levels being caused directly and indirectly by climate change.
GRACE Fast Mascons From Spherical Harmonics and a Regularization Design Trade Study
Authors: Croteau M. J. , Sabaka T. J. , Loomis B. D. 
Published: July 2021

AbstractMass concentration (mascon) solutions have become a prominent medium for investigating time‐variable gravity recovered by GRACE and GRACE Follow‐On. While GRACE Level‐2 spherical harmonic products require various postprocessing techniques to eliminate correlated noise, mascon formulations employ spatial regularization strategies during the estimation step to improve signal recovery. However, mascon estimation has traditionally required large computing resources and GRACE Level‐1B processing capabilities. In this study, we show that a typical mascon estimation system can be reformulated to allow for the estimation of regularized mascons from Level‐2 spherical harmonics. Provided that spherical harmonic solution covariances are available, the computed mascons will be mathematically equivalent to similar mascons estimated from Level‐1B observations. This method is computationally efficient, better leverages GRACE spherical harmonics than past methods, and matches the performance of typical mascon solutions without locking scientists into predetermined regularization designs. We develop a proof‐of‐concept solution using ITSG‐Grace2018 and compare results with traditional mascons from the Jet Propulsion Lab (JPL) and NASA Goddard Space Flight Center (GSFC). We then assess the effects of spherical harmonic truncation and use of regularization correlations on basin signal recovery. We find that spherical expansions to degree and order 60 provide the minimum expansion necessary to study most basins, while larger expansions help further localize signals. We also find that diagonal regularizations (i.e., regularizations that do not contain inter‐mascon correlations) are adversely affected by leakage, especially across boundaries such as coastlines where signals are not highly correlated, whereas including inter‐mascon correlations and regional boundaries in the regularization greatly improves signal recovery.
Particulate Export of PAHs Firstly Traced by 210Po/210Pb Disequilibrium: Implication on the “Shelf Sink Effect” in the Arctic Ocean
Authors: Liu M. , Chen M. , Duan M. , Lin Y. , Liu X. , Liang J. , Ke H. , Li H. , Chen M. , Cai M. 
Published: July 2021

AbstractIn the changing Arctic Ocean, organic pollutants' transport and biogeochemical processes are strongly influenced by their particulate export on the broad continental shelf. To better evaluate the vertical particulate export of polycyclic aromatic hydrocarbons (PAHs), seawater samples were collected from the Bering Sea, Chukchi Sea, and Canada Basin with the first application of 210Po/210Pb disequilibrium during the summer of 2012. Dissolved PAHs (1.1–19 ng L−1, mean 5.2 ± 3.6 ng L−1) showed spatial distinctions, with high values on the Bering Shelf and low values in the Chukchi Sea, while particulate PAHs (1.0–12 ng L−1, mean 5.0 ± 3.5 ng L−1) showed high levels in the nutrient‐rich Bering Shelf Water layer. According to the 210Po/210Pb deficit on the Bering Shelf, the export fluxes of particulate PAHs ranged from 1,201 ± 276 to 3,650 ± 1,570 ng m−2 d−1, and their residence time ranged from 55 ± 23 to 133 ± 31 days. From the Bering Shelf to the Chukchi Sea, the decreased inventories of dissolved PAHs were positively related to their vertical particulate export fluxes (R2 = 0.62), suggesting the “Shelf Sink Effect” on PAHs.
5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding
Authors: He Yanlin , Cai Xing , Liu Hailan , Conde Krisitine M. , Xu Pingwen , Li Yongxiang , Wang Chunmei , Yu Meng , He Yang , Liu Hesong , Liang Chen , Yang Tingting , Yang Yongjie , Yu Kaifan , Wang Julia , Zheng Rong , Liu Feng , Sun Zheng , Heisler Lora , Wu Qi , Tong Qingchun , Zhu Canjun , Shu Gang , Xu Yong 
Published: July 2021

AbstractObesity is primarily a consequence of consuming calories beyond energetic requirements, but underpinning drivers have not been fully defined. 5-Hydroxytryptamine (5-HT) neurons in the dorsal Raphe nucleus (5-HTDRN) regulate different types of feeding behavior, such as eating to cope with hunger or for pleasure. Here, we observed that activation of 5-HTDRN to hypothalamic arcuate nucleus (5-HTDRN → ARH) projections inhibits food intake driven by hunger via actions at ARH 5-HT2C and 5-HT1B receptors, whereas activation of 5-HTDRN to ventral tegmental area (5-HTDRN → VTA) projections inhibits non-hunger-driven feeding via actions at 5-HT2C receptors. Further, hunger-driven feeding gradually activates ARH-projecting 5-HTDRN neurons via inhibiting their responsiveness to inhibitory GABAergic inputs; non-hunger-driven feeding activates VTA-projecting 5-HTDRN neurons through reducing a potassium outward current. Thus, our results support a model whereby parallel circuits modulate feeding behavior either in response to hunger or to hunger-independent cues.
DCision-making in tumors governs T cell anti-tumor immunity
Authors: Alfei Francesca , Ho Ping-Chih , Lo Wan-Lin 
Published: July 2021

AbstractThe exploitation of T cell-based immunotherapies and immune checkpoint blockade for cancer treatment has dramatically shifted oncological treatment paradigms and broadened the horizons of cancer immunology. Dendritic cells have emerged as the critical tailors of T cell immune responses, which initiate and coordinate anti-tumor immunity. Importantly, genetic alterations in cancer cells, cytokines and chemokines produced by cancer and stromal cells, and the process of tumor microenvironmental regulation can compromise dendritic cell–T cell cross-talk, thereby disrupting anti-tumor T cell responses. This review summarizes how T cell activation is controlled by dendritic cells and how the tumor microenvironment alters dendritic cell properties in the context of the anti-tumor immune cycle. Furthermore, we will highlight therapeutic options for tailoring dendritic cell-mediated decision-making in T cells for cancer treatment.
Visual attention during pediatric resuscitation with feedback devices: a randomized simulation study
Authors: Wagner Michael , Gröpel Peter , Eibensteiner Felix , Kessler Lisa , Bibl Katharina , Gross Isabel T. , Berger Angelika , Cardona Francesco S. 
Published: July 2021

Abstract
Background
The aim of this study was to investigate the effect of feedback devices on visual attention and the quality of pediatric resuscitation.

Methods
This was a randomized cross-over simulation study at the Medical University of Vienna. Participants were students and neonatal providers performing four resuscitation scenarios with the support of feedback devices randomized. The primary outcome was the quality of resuscitation. Secondary outcomes were total dwell time (=total duration of visit time) on areas of interest and the workload of participants.

Results
Forty participants were analyzed. Overall, chest compression (P < 0.001) and ventilation quality were significantly better (P = 0.002) when using a feedback device. Dwell time on the feedback device was 40.1% in the ventilation feedback condition and 48.7% in the chest compression feedback condition. In both conditions, participants significantly reduced attention from the infant’s chest and mask (72.9 vs. 32.6% and 21.9 vs. 12.7%). Participants’ subjective workload increased by 3.5% (P = 0.018) and 8% (P < 0.001) when provided with feedback during a 3-min chest compression and ventilation scenario, respectively.

Conclusions
The quality of pediatric resuscitation significantly improved when using real-time feedback. However, attention shifted from the manikin and other equipment to the feedback device and subjective workload increased, respectively.

Impact

Cardiopulmonary resuscitation with feedback devices results in a higher quality of resuscitation and has the potential to lead to a better outcome for patients.

Feedback devices consume attention from resuscitation providers.

Feedback devices were associated with a shift of visual attention to the feedback devices and an increased workload of participants.

Increased workload for providers and benefits for resuscitation quality need to be balanced for the best effect.