bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endovascular snare technique to facilitate delivery of self‐expanding valve during transcatheter aortic valve‐in‐valve replacement in angulated aortas: A case series
Authors: Rohm Charlene L. , Farhat Salman , Al‐Hijji Mohammed , Goel Kashish , Greason Kevin , Gulati Rajiv , el Sabbagh Abdallah 
Published: January 2021

AbstractBackgroundTranscatheter aortic valve‐in‐valve replacement (ViV) has been widely accepted as a less invasive alternative to treat failed aortic surgical or transcatheter bioprosthetic valves. Angulated aortas present an additional challenge, particularly when using self‐expanding transcatheter heart valves (SE‐THV).MethodsTwo patients with failed surgical bioprosthetic aortic valves and one patient with a failed transcatheter bioprosthetic aortic valve underwent transcatheter aortic ViV using SE‐THV. All were deemed high‐risk for surgical aortic valve replacement by a heart team. All three patients had initial failed SE‐THV delivery using a conventional approach with subsequent successful delivery using the endovascular snare technique.ResultsIn Cases 1 and 2, the SE‐THV was biased towards the greater curve of the angulated aorta and behind the outer frame of the bioprosthetic valve frame. An endovascular snare was deployed through a secondary left femoral artery access, and the valve delivery system was advanced through the snare in the ascending aorta. The snare was tightened around the SE‐THV capsule proximal to the hat‐marker, allowing deflection of the SE‐THV and successful delivery. In Case 3, the SE‐THV interacted with the tall frame of a failed SE‐THV. A snare via the left femoral artery was deployed in the descending artery. The SE‐THV was advanced through the snare, and both the snare and SE‐THV were advanced together to the ascending aorta where the SE‐THV was deflected and successfully delivered.ConclusionsThe endovascular snare technique is a feasible option for successful delivery of SE‐THV during transcatheter aortic ViV in failed transcatheter or surgical bioprosthetic valves in angulated aortas.
Transcatheter Fontan completion using novel balloon and stent system
Authors: Aregullin E. Oliver , Mohammad Nijres Bassel , Al‐Khatib Yasser , Vettukattil Joseph 
Published: January 2021

AbstractDespite advances in percutaneous interventions, transcatheter Fontan completion remains experimental and performed only in select cases. Non‐surgical Fontan completion requires surgical preconditioning at an earlier stage of palliation. We describe transcatheter Fontan completion in a 15‐year‐old male with previously failed surgical Fontan palliation without surgical preconditioning.
Novel strategy for ostial left anterior descending artery acute myocardial infarction: Combined treatment with directional coronary atherectomy followed by drug‐coated balloon angioplasty
Authors: Yamamoto Hiroyuki , Sawada Takahiro , Takaya Tomofumi , Kawai Hiroya , Yasaka Yoshinori 
Published: January 2021

AbstractA 69‐year‐old female diagnosed with ostial left anterior descending artery acute myocardial infarction underwent percutaneous coronary intervention using combined directional coronary atherectomy followed by drug‐coated balloon angioplasty. This report highlights a novel management strategy with no permanent scaffold left in the coronary artery.
Conflicting clinical and radiological management decisions
Authors: Zaalouk Tamer Mohamed , Bitar Zouheir Ibrahim , Maadarani Ossama Sajeh 
Published: January 2021

AbstractGliosis with hemorrhagic transformation is a late reported complication of stroke. Sometimes there is a big discrepancy between clinical and radiological diagnosis, and clinical decisions must be multi‐aspect decisions and not dependent on a single discrepant investigation result.
A call for individualized evacuation strategies for floods: A case report of secondary surgical site infection in a postsurgery breast cancer patient in Fukushima, Japan, following Typhoon Hagibis in 2019
Authors: Ozaki Akihiko , Kanemoto Yoshiaki , Wada Masahiro , Kurokawa Tomohiro , Kawamoto Ayumu , Sawano Toyoaki , Bhandari Divya , Tsubokura Masaharu , Tanimoto Tetsuya , Ejiri Tomozo , Kanzaki Norio 
Published: January 2021

AbstractRecognition of Individual and environmental risks is crucial to alleviate damage inflicted by disasters. In particular, an awareness of floods and their health risks in patients’ residences is important for patients and their healthcare professionals.
A case of cardiopulmonary arrest due to left ventricular free wall rupture successfully treated with sutureless repair supported by venoarterial extracorporeal membrane oxygenation
Authors: Suzuki Ginga , Ichibayashi Ryo , Yamamoto Saki , Serizawa Hibiki , Kawada Kota , Kameda Toru , Nakamichi Yoshimi , Watanabe Masayuki , Okuma Shinnosuke , Honda Mitsuru 
Published: January 2021

AbstractExtracorporeal membrane oxygenation for cardiopulmonary arrest due to left ventricular free wall rupture is considered effective, because it enables rapid cardiopulmonary support and introduction of targeted temperature management.
Outside the box—Surgery for aggressive plasmacytoma in scar
Authors: Fliss Ehud , Zaretski Arik , Cohen Yael , Shapira Yuval , Gur Eyal , Yanko Ravit 
Published: January 2021

AbstractThis report introduces the concept of large‐scale surgery and reconstruction when all other medical means of treatment have failed. In select cases, this may act as a mode of buying time and allowing the patient to receive second‐ or third‐line treatments.
Overlap between EBV‐positive diffuse large B‐cell lymphoma, NOS, in a young patient and angioimmunoblastic T‐cell lymphoma: A diagnostic pitfall
Authors: Kim Chae Hwa , Ghaffaripour Taban , Zhou Yi , Chapman Jennifer R. 
Published: January 2021

AbstractThere may be significant histopathologic overlap between EBV‐positive DLBCL, NOS, and other diagnoses including angioimmunoblastic T‐cell lymphoma (AITL). Resolution of this differential diagnosis may be particularly challenging and require extensive investigation of clinicopathologic features.
Fighting diagnostic confirmation bias: Cystic fibrosis, allergic bronchopulmonary aspergillus, or both?
Authors: Choi Patricia , Bauler Laura , Gregoire‐Bottex M. Myrtha 
Published: January 2021

AbstractAs diagnostic algorithms for cystic fibrosis (CF) continue to evolve, education of general practitioners is essential to prevent delayed diagnosis of CF and allow prompt referral to CF centers. For patients suffering from allergic bronchopulmonary aspergillosis (ABPA), CF should be at the top of the differential diagnosis.
Mass Transfer Behavior of a Rotating Hexagonal Cylinder Reactor Suitable for Water Pollution Control
Authors: Saad Eldin Mohamed H. , Nosier Shaban A. , Abdel-Aziz Mohamed H. , Hussein Mohamed , Sedahmed Gomaa H. 
Published: January 2021

AbstractRates of mass transfer at a rotating cylinder of the hexagonal cross section were measured by the limiting current method. A drag‐reducing polymer diminished the speed of mass transfer depending on polymer quantity and rotation speediness. Rotating hexagonal cylinders provided higher degrees of mass transfer than circular rotating cylinders under identical conditions. The performance of rotating hexagonal cylinders in eliminating Cu2+ from dilute liquids was examined and found to be satisfactory. Besides the diffusion‐controlled electrochemical reactions like anodic oxidation of organic contaminants, the reactor can remove organic pollutants via catalytic diffusion‐controlled reactions. The high degree of heat transfer from the cylinder to the liquid would prevent possible hot spots, catalyst deactivation, and decomposition of products.
Enantioselective conjugate addition of pyrazolones to nitroalkenes catalyzed by chiral squaramide organocatalyst
Authors: Aydin Alime Ebru , Culha Selda 
Published: January 2021

AbstractThe chiral squaramide catalysts (8–15) were synthesized, and their catalytic efficiency in the enantioselective conjugate addition of pyrazolones to nitroalkenes was described. This protocol provides excellent chemical yields (up to 93%) of chiral 5‐methyl‐4‐(2‐nitro‐1‐arylethyl)pyrazol‐3‐ol derivatives with high enantioselectivities (up to 97% ee).
Effect of zero‐valent iron nanoparticles on the remediation of a clayish soil contaminated with γ‐hexachlorocyclohexane (lindane) in a bioelectrochemical slurry reactor
Authors: Mar‐Pineda Catherine G. , Poggi‐Varaldo Héctor M. , Ponce‐Noyola M. Teresa , Estrada‐Bárcenas Daniel A. , Ríos‐Leal Elvira , Esparza‐García Fernando J. , Galíndez‐Mayer Juvencio , Rinderknecht‐Seijas Noemí F. 
Published: January 2021

AbstractIn this research we evaluated the effect of adding zero‐valent iron nanoparticles (ZVI‐NP) to a complete mix bioelectrochemical slurry reactors (BESR) on the remediation of a clayish soil with a high content of organic matter, contaminated with lindane. Five BESR were loaded with a clayish polluted soil (100 mg lindane/kgds), known concentrations of ZVI‐NP, liquid medium, and sulphate‐reducing inoculum to give a 33% w/v soil concentration. A one‐factor experimental design was used, where the effect of nanoparticles concentration [NP] on lindane removal efficiency (ηlin) and other response variables were evaluated. The [NP] levels were 0.0 (background control with electrical connection, BCWC), 2.5 (Exp1), 5.0 (Exp2), and 7.5 gNP/kgds (Exp3). Maximum ηlin (95%) was attained in Exp2 (5 gNP/kgds). Beyond this level the ηlin slightly decreased (Exp3 with 85% ηlin.) Approximately 40%‐57% of lindane was removed in the first 24 hours during a rapid kinetics phase. No metabolites of lindane degradation were detected after 30 days of operation in all the BESR. Energy production increased with [NP]; Exp3 generated 4.3 MJ/tonneds at 30 days, whereas the other treatments produced energy between 1.6 MJ/tonneds‐1.2 MJ/tonneds. Bioelectrical energy could partially offset the requirements of BESR mixing energy. Overall performance evaluation using an ad hoc multicriteria framework indicated that BESR followed the order Exp2 > Exp3 > Exp1 ~ BCWC > ABCWOC (abiotic control without electrical connection). There was a significant, positive effect of the combined BESR and ZVI‐NP technology for the remediation of heavy soils contaminated with lindane.
Bridging from the Sequence to Architecture: Graft Copolymers Engineering via Successive Latent Monomer and Grafting‐from Strategies†
Authors: Zhang Yajie , Cao Xiaohuan , Gao Yang , Xie Yujie , Huang Zhihao , Zhang Zhengbiao , Zhu Xiulin 
Published: January 2021

Main observation and conclusionThe on‐demand building copolymer structures, from sequence to architecture, is crucial in understanding the relation between polymer structure and property, meanwhile motivating the innovation of polymer hierarchy. However, the challenge is conspicuous for complicated polymer structures from inherently intricate polymerization. In this work, copolymers with tailored grafting density and distributions were achieved using successive latent monomer and grafting‐from strategies. The hydroxyl group functionalized furan/maleimide adduct (FMOH) was selected as the latent monomer for RAFT polymerization of an array of copolymers with tailored localization of hydroxyl group along the main chain. The hydroxyl group further initiated the ring opening polymerization (ROP) of L‐lactide or ε‐caprolactone, resulting in a library of multicomponent copolymers via grafting‐from strategy. The initiating efficiency reached to ~100% with variable molecular weight (21300—58600 Da) and narrow distributions (ÐM < 1.25), indicating that such graft copolymers possessed controlled density and distribution of side chains as its linear template. The investigation on thermal properties of the well‐defined graft copolymers implied that the precise tailoring over copolymer structures at the molecule level could lead to tunable chemical/physical properties. This work bridged polymer from sequence to architecture, unveiled a new method in creating graft copolymers with programmable structures and provided the insight into the structure/property relationship.
In Situ Characterization of Transformations in Nanoscale Layered Metal Chalcogenide Materials: A Review
Authors: Kondekar Neha , Shetty Pralav P. , Wright Salem C. , McDowell Matthew T. 
Published: January 2021

AbstractLayered metal chalcogenide materials, such as MoS2 and Bi2Te3, have found important applications as 2D materials in emerging electronic devices. To create nanoscale layered chalcogenide materials with precisely controlled structures and properties, it is critical to understand and control how they evolve and transform under various conditions. This Minireview presents an overview of recent research focused on using in situ characterization to understand the atomic‐scale details of transformations during growth, under exposure to reactive chemical and thermal environments, and on interfacing with other materials. These efforts have used techniques including in situ transmission electron microscopy (TEM), X‐ray spectroscopy, and optical methods to understand nanoscale transformations. These in situ studies have provided a substantially improved understanding of transformation mechanisms in layered chalcogenide materials, which is an important step toward the use of these interesting materials in a variety of electronic and electrochemical devices.
Membrane Fusion Models for Bioapplications
Authors: Mazur Federico , Chandrawati Rona 
Published: January 2021

AbstractMembrane fusion is a highly evolved and significant physiological process involving the mixing of two initially distinct lipid bilayer membranes. It is concerned with communication between and within cells and plays a key role in various processes such as exocytosis, endocytosis, fertilization, viral infection, and carcinogenesis. Due to its significant role, artificial model systems using lipid membranes have been developed over the last few decades which study the membrane fusion mechanism on a molecular level. More recently, this field of research has shifted its attention towards the use of these developed models for a diverse range of biomolecular and biomedical applications. This review will focus on current applications which stem from these models including drug delivery, sensing, protocell proliferation, and others. Our opinions on the future advancements of this field will also be included.
B, N Co‐doped Nanocarbon Derived In Situ from Nanoboron Carbide as Electrocatalyst for Oxygen Reduction Reaction
Authors: Zhou Shuyu , Zang Jianbing , Li Wei , Tian Pengfei , Gao Hongwei , Song Shiwei , Tian Xueqing , Wang Yanhui 
Published: January 2021

AbstractHeteroatom‐doped metal free carbon materials, especially boron and nitrogen co‐doped carbons have been widely researched as promising oxygen reduction electrocatalysts because of their low cost, high activity and environmental friendliness. However, B, N‐doped carbon electrocatalysts are usually prepared at high temperature and accompanied by the formation of B−N bonds resulting in the inactivation of the active sites. This paper proposed a strategy for synthesizing B and N co‐doped carbons for oxygen reduction reaction in‐situ derived from nano‐boron carbide by one‐step heat treatment at low temperature. This strategy can produce B‐ and N‐doped active sites while avoiding formation of B−N bonds, allowing electrocatalysts to exhibit excellent catalytic activities (Eonset=0.93 V, E1/2=0.79 V) and better stability (current density remained 93.3% after 12,000 s) comparable to commercial Pt/C (20 wt%). New ideas were provided by this work to massively produce the B and N co‐doped carbon electrocatalysts candidates for ORR.
Two Polyoxometalate‐Based Hybrid Compounds Modified by Iron Schiff Base Complexes: Syntheses, Crystal structures, Cyclic Voltametric Studies and Nonlinear Optical Properties
Authors: Wang Ji‐Lei , Yang Mu‐Xiu , Zhu Yu‐Xuan , Cao Jia‐Peng , Du Ze‐Yu , Li Jia‐Nian , Liu Xiao‐Mei , Xu Yan 
Published: January 2021

AbstractTwo new polyoxometalate (POM)‐based hybrid compounds modified by a Schiff base, [Fe(DAPSC)(H2O)2]2[HPMo2VMo10VIO40] ⋅ 5H2O (1) and [Fe(DAPSC)(H2O)]2[HPV3IVMo4VMo7VIO42] ⋅ 6H2O (2), (DAPSC=2,6‐diacetylpyridine bis‐(semicarbazone)), have been successfully constructed from typical Keggin POMs, iron ions, and DAPSC ligands under hydrothermal condition. Structural analysis demonstrates that the Fe‐Schiff base ligand units are free from polyacid anions in compound 1. While in compound 2, the Fe‐Schiff base ligand units are bridged with polyacid anions via Fe−O bonds to emerge a stable double‐supported skeleton. Noticeably, owing to the introduction of vanadium in H5PMo10V2O40 ⋅ 32.5H2O, a divanadium‐capped configuration is shaped in compound 2. Besides, the third‐order nonlinear optical (NLO) properties of two compounds were explored. It should be noted that both compounds 1 and 2 have two‐photon absorption properties, which indicates that the two compounds are potential nonlinear optical materials.
Light‐Induced Electron Transfer in Manganese(V)–Oxo Corroles
Authors: Wang Li‐Li , Wan Bei , Lai Shu‐Hui , Weng Lin‐Fang , Liu Hai‐Yang , Wang Hui 
Published: January 2021

AbstractElectron and proton transfer reactions are essential elements in water oxidation by the oxygen‐evolving complex of photosystem II. To date manganese(V)–oxo corrole has successfully mimicked the oxygen evolution reaction. We report here ultrafast intramolecular electron transfer (ET) in corrole manganese (Mn) complexes. With femtosecond spectroscopy, the evolutions of transient absorption spectra of three kinds of Mn(V)–oxo corroles were measured. A ∼0.17 ps ET process has been observed in (OHF10C)MnV(O) after photoexcitation at 400 nm, which is absent for (F15C)MnV(O) and (F10C)MnV(O). The back ET is different from that of Mn(III) corrole ((OHF10C)MnIII), being a ∼12.3 ps ET followed by a very long ground‐state recovery. The mechanism of the ET observed in (OHF10C)MnV(O) has been discussed. The result reveals that the natural O−O bond formation may include ultrafast ET among the calcium‐ligated hydroxide, Mn(V), and the oxygen bound to the metal ion.
Gingival cell growth with antiresorptive treatment combined with corticosteroids or antiestrogen
Authors: Ekholm Heidi M. , Löyttyniemi Eliisa , Soukka Tero , Rautava Jaana 
Published: January 2021

AbstractObjectivesAntiresorptive treatment has been shown to impair mucosal cell proliferation, migration, and viability. However, in the clinic, antiresorptives are often used in combination with other drugs. We studied the effect of antiresorptives combined with a corticosteroid or antiestrogen on oral mucosal keratinocytes and fibroblasts.Material and methodsHuman gingival keratinocyte and fibroblast cell lines were exposed to bisphosphonates (BPs) and denosumab in different concentrations and durations together with an antiestrogen or corticosteroid. Changes in cell viability, proliferation and migration after exposures were measured. Data were evaluated with hierarchical linear mixed model for repeated measurements.ResultsBisphosphonate exposure suppressed keratinocyte and fibroblast cell viability, proliferation, and migration in a time‐dependent manner. Combining a corticosteroid or antiestrogen with BPs further increased this negative effect. Denosumab alone had a mild positive effect on keratinocyte and fibroblast growth. When denosumab was combined with a corticosteroid or antiestrogen, cell growth was suppressed.ConclusionsOur results show that coexisting medications may increase the negative impact of BPs or denosumab on oral mucosal cells.
Self‐sustained solitary waves in a tunnel diode oscillator lattice and their applications in frequency division
Authors: Narahara Koichi 
Published: January 2021

SummarySelf‐sustained solitary waves, which propagate in a one‐dimensional lattice of tunnel diode (TD) oscillators, can be effectively applied to frequency division. In this work, it is experimentally observed that the properties of a solitary wave strongly suggest that it is the discretized counterpart of the homoclinic pulse predicted in a quasi‐continuous model of a TD oscillator lattice. Generally, these self‐sustained waves annihilate during a head‐on collision. Owing to this phenomenon, a TD oscillator lattice acts as an efficient frequency divider through its simple connection to an ordinary LC ladder circuit. In this work, both the pair annihilation of pulses and a 2:1 frequency division ratio are successfully observed experimentally.
An interharmonic dual switching frequency modulation strategy for impedance network inverters
Authors: Mohammadi Mohammad , Moghani Javad S. , Mattavelli Paolo , Khoshsaadat Alireza , Mahdi Asghari Mohammad , Milimonfared Jafar 
Published: January 2021

SummaryRecently, a novel dual switching frequency modulation (DFM) has been proposed for impedance network inverters (INIs). The proposed approach allows the INIs to be designed optimally in size and efficiency, for motor drive applications. Moreover, DFM provides the possibility of operation with unity modulation index. However, DFM requires a high‐frequency ratio between pulse‐width modulation (PWM) and sinusoidal PWM (SPWM) switching frequencies. This paper proposes an improved modulation strategy to overcome this issue. The modulation called interharmonic dual frequency modulation (IDFM) utilizes the interharmonic areas of a conventional sinusoidal PWM to implement DFM. The proposed approach gives a low total harmonic distortion (THD) output voltage without increasing the frequency ratio of PWM and SPWM. IDFM provides the possibility of selecting a wide range of frequencies for both switching modulations. The approach is explained theoretically, compared with other switching strategies, and also the simulation and experimental results are used to validate its performance.
Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells
Authors: Li Bowen , Wang Zhiwei , Hong Junmou , Che Yanjia , Chen Ruoshi , Hu Zhipeng , Hu Xiaoping , Wu Qi , Hu Junxia , Zhang Min 
Published: January 2021

AbstractBackgroundAortic dissection (AD) and aortic aneurysm (AA) are critical illnesses with an unclear pathogenetic mechanism that seriously threaten human life. Aortic medial degeneration (AMD) is the main pathological feature of AD and AA. Diseases of iron metabolism can cause a variety of physiological dysfunctions. In this study, we aimed to clarify the state of iron metabolism in patients with AD and AA, and to explore the effect of iron metabolism on AMD.MethodsA total of 200 patients with AD or AA, and 60 patients with hypertension were included in the study. Blood samples were drawn immediately when patients were admitted to the hospital. Aortic specimens from patients with Stanford type A AD were obtained at the time of surgery. The status of iron metabolism in the circulation and the aortic wall was analyzed. In addition, apolipoprotein E knockout mice were fed chow with a different iron content, and angiotensin II (Ang II) was used to induce AMD. Furthermore, transferrin receptor 1 knockout (TFR1−/−) mice were used to study the effects of iron deficiency (ID) on aortic development, to observe the effects of different iron metabolism status on the formation of AMD in mice, and to explore the cytoskeleton of vascular smooth muscle cells (VSMCs) under different iron metabolism.ResultsPatients with AMD were iron deficient. ID is associated with the development of AMD in hypertensive patients. Iron‐deficient feeding combined with Ang II pumping promoted the formation of AMD and significantly shortened the survival time of mice. ID significantly impaired the cytoskeleton of VSMCs.Conclusions: Our results highlighted that ID was associated with the formation of AMD in patients with hypertension. In this study, we identified a novel mechanism behind VSMCs dysfunction that was induced by ID, thereby suggesting iron homeostasis as a future precaution in patients with hypertension based on its important role in the maintenance of VSMC function.