bluuebunny/crossref_metadata_2025_split huggingface dataset:
Managing sustainability risks of bioenergy in four Nordic countries
Authors: Hansen Anders Chr. , Clarke Nicholas , Hegnes Atle Wehn 
Published: June 2021

AbstractBackgroundBioenergy plays a key role in the transition to a sustainable economy in Europe, but its own sustainability is being questioned. We study the experiences of Sweden, Finland, Denmark and Norway, to find out whether the forest-based bioenergy chains developed in the four countries have led to unsustainable outcomes and how the countries manage the sustainability risks. Data were collected from a diversity of sources including interviews, statistical databases, the scientific literature, government planning documents and legislation.ResultsSustainability risks of deforestation, degradation of forests, reduced carbon pools in forests, expensive biopower and heat, resource competition, and lack of acceptance at the local level are considered. The experience of the four countries shows that the sustainability risks can to a high degree be managed with voluntary measures without resorting to prescriptive measures. It is possible to add to the carbon pools of forests along with higher harvest volumes if the risks are well managed. There is, however, a marginal trade-off between harvest volume and carbon pools. Economic sustainability risks may be more challenging than ecological risks because the competitiveness order of renewable energy technologies has been reversed in the last decade. The risk of resource competition harming other sectors in the economy was found to be small and manageable but requires continuous monitoring. Local communities acting as bioenergy communities have been agents of change behind the most expansive bioenergy chains. A fear of non-local actors reaping the economic gains involved in bioenergy chains was found to be one of the risks to the trust and acceptance necessary for local communities to act as bioenergy communities.ConclusionsThe Nordic experience shows that it has been possible to manage the sustainability risks examined in this paper to an extent avoiding unsustainable outcomes. Sustainability risks have been managed by developing an institutional framework involving laws, regulations, standards and community commitments. Particularly on the local level, bioenergy chains should be developed with stakeholder involvement in development and use, in order to safeguard the legitimacy of bioenergy development and reconcile tensions between the global quest for a climate neutral economy and the local quest for an economically viable community.
Food consumption patterns, nutrient adequacy, and the food systems in Nigeria
Authors: Mekonnen Daniel A. , Trijsburg Laura , Achterbosch Thom , Brouwer Inge D. , Kennedy Gina , Linderhof Vincent , Ruben Ruerd , Talsma Elise F. 
Published: June 2021

AbstractPrevious studies in Nigeria examined food and nutrition security mainly using anthropometric indicators, total calorie intake, or the household dietary diversity score (HDDS). However, recent evidence on nutrient and dietary gaps, especially from nationally representative surveys, is weak. This study contributes by examining factors influencing household mean nutrient adequacy and HDDS with focus on components of food systems in Nigeria. Based on the 2015/16 Nigeria General Household Survey, we found that fruits and animal source foods were the least consumed food groups. Yet, these food groups seem to be the main sources of difference in HDDS and were strongly associated with the mean probability of nutrient adequacy, given covariates. Among 11 nutrients under study, large shortfalls were observed in consumption of iron, vitamin B12, and riboflavin with probability of adequacy being 0.2 or below, followed by niacin, vitamin C, and zinc with corresponding probability of adequacy ranged between 0.48 and 0.58. Further, results suggested that mobile phone ownership by the household head, household’s access to electricity, improved sources of water for household consumption, and percent of the community with improved sanitation were strongly associated with HDDS. Heterogeneities in food groups and nutrient consumption and food system drivers are discussed.
Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences
Authors: Ganel Liron , Chen Lei , Christ Ryan , Vangipurapu Jagadish , Young Erica , Das Indraniel , Kanchi Krishna , Larson David , Regier Allison , Abel Haley , Kang Chul Joo , Scott Alexandra , Havulinna Aki , Chiang Charleston W. K. , Service Susan , Freimer Nelson , Palotie Aarno , Ripatti Samuli , Kuusisto Johanna , Boehnke Michael , Laakso Markku , Locke Adam , Stitziel Nathan O. , Hall Ira M. 
Published: June 2021

Abstract

Background

Mitochondrial genome copy number (MT-CN) varies among humans and across tissues and is highly heritable, but its causes and consequences are not well understood. When measured by bulk DNA sequencing in blood, MT-CN may reflect a combination of the number of mitochondria per cell and cell-type composition. Here, we studied MT-CN variation in blood-derived DNA from 19184 Finnish individuals using a combination of genome (N = 4163) and exome sequencing (N = 19034) data as well as imputed genotypes (N = 17718).

Results

We identified two loci significantly associated with MT-CN variation: a common variant at the MYB-HBS1L locus (P = 1.6 × 10−8), which has previously been associated with numerous hematological parameters; and a burden of rare variants in the TMBIM1 gene (P = 3.0 × 10−8), which has been reported to protect against non-alcoholic fatty liver disease. We also found that MT-CN is strongly associated with insulin levels (P = 2.0 × 10−21) and other metabolic syndrome (metS)-related traits. Using a Mendelian randomization framework, we show evidence that MT-CN measured in blood is causally related to insulin levels. We then applied an MT-CN polygenic risk score (PRS) derived from Finnish data to the UK Biobank, where the association between the PRS and metS traits was replicated. Adjusting for cell counts largely eliminated these signals, suggesting that MT-CN affects metS via cell-type composition.

Conclusion

These results suggest that measurements of MT-CN in blood-derived DNA partially reflect differences in cell-type composition and that these differences are causally linked to insulin and related traits.
Efficacy of affirmative cognitive behavioural group therapy for sexual and gender minority adolescents and young adults in community settings in Ontario, Canada
Authors: Craig Shelley L. , Eaton Andrew D. , Leung Vivian W. Y. , Iacono Gio , Pang Nelson , Dillon Frank , Austin Ashley , Pascoe Rachael , Dobinson Cheryl 
Published: June 2021

Abstract
Objective
This study tested the efficacy of AFFIRM, a brief affirmative cognitive-behavioural group intervention tailored to reduce psychosocial distress and improve coping among sexual and gender minority adolescents and young adults (SGMY).

Method
SGMY (n = 138; M age = 22.44) were allocated to immediate 8-week AFFIRM intervention delivered at 12 community-based organisations or an 8-week waitlisted control. At baseline, post-intervention or post-waitlist, participants completed self-reported assessments of depression, hope, coping, and stress appraisal. Implementation outcomes of feasibility and acceptability were also assessed.

Results
Compared to waitlist, SGMY in the intervention condition significantly reduced their depressive symptoms (b = − 5.79, p = .001) as well as increased reports of hope (agency: b = 0.84, p = .001; pathway: b = 0.79, p = .001), and coping by emotional support (b = 0.59, p < .001), instrumental support (b = 0.67, p < .001), positive framing (b = 0.59, p < .001), humour (b = 0.36, p = .014), planning (b = 0.49, p < .001) as well as reflective coping (b = 0.27, p = .009). Intervention participants were also less likely to perceive stress as a threat (b = − 0.43, p = .001), and more likely to perceive stress as challenge (b = 0.67, p < .001) and have the resources to deal with that stress (b = 0.38, p = .016) in comparison to waitlisted control participants. All outcomes had medium to large effect sizes. AFFIRM participants reported low attrition (8.5%) and high levels of engagement and acceptability (e.g. 99% agreed intervention was relevant to their lives). Over 63% of the community organizations that participated in the training hosted AFFIRM at least once during the study.

Conclusions
Results demonstrate efficacy for the community-based implementation of an affirmative clinical intervention designed for SGMY to address depression and foster coping with universal and minority stressors.
Evaluation of erosion characteristics of soils using the pinhole test
Authors: Dinh Ba Huu , Nguyen Anh-Dan , Jang Seo-Yong , Kim Young-Sang 
Published: June 2021

AbstractThis paper investigates the erosion characteristics of soils using the pinhole test. The tests were conducted with two undisturbed clay samples and five disturbed sandy soil samples. Based on the pinhole test results, a process to analyze the critical shear stress and erosion rate was proposed. The result indicates that the particle size distribution and coefficient of uniformity of soils are significant factors that affect the erosion characteristics of the soil. Samples with a grain size ranging from 0.2 to 0.6 mm is most susceptible to soil erosion. The erosion coefficients can be used to distinguish between the low erodible soils (ND3 and ND4) and high erodible ones (D1 and D2). Furthermore, it is interesting to note that the critical shear stress might be used as an identification parameter for erosion characteristics of the soil: τc > 3.5 Pa (ND3), 3.0 Pa < τc < 3.5 Pa (D2), and τc < 3.0 Pa (D1).
Bioelectrical impedance analysis-guided fluid management promotes primary fascial closure after open abdomen: a randomized controlled trial
Authors: Wang Kai , Sun Shi-Long , Wang Xin-Yu , Chu Cheng-Nan , Duan Ze-Hua , Yang Chao , Liu Bao-Chen , Ding Wei-Wei , Li Wei-Qin , Li Jie-Shou 
Published: June 2021

Abstract
Background
Fluid overload (FO) after resuscitation is frequent and contributes to adverse outcomes among postinjury open abdomen (OA) patients. Bioelectrical impedance analysis (BIA) is a promising tool for monitoring fluid status and FO. Therefore, we sought to investigate the efficacy of BIA-directed fluid resuscitation among OA patients.

Methods
A pragmatic, prospective, randomized, observer-blind, single-center trial was performed for all trauma patients requiring OA between January 2013 and December 2017 to a national referral center. A total of 140 postinjury OA patients were randomly assigned in a 1:1 ratio to receive either a BIA-directed fluid resuscitation (BIA) protocol that included fluid administration with monitoring of hemodynamic parameters and different degrees of interventions to achieve a negative fluid balance targeting the hydration level (HL) measured by BIA or a traditional fluid resuscitation (TRD) in which clinicians determined the fluid resuscitation regimen according to traditional parameters during 30 days of ICU management. The primary outcome was the 30-day primary fascial closure (PFC) rate. The secondary outcomes included the time to PFC, postoperative 7-day cumulative fluid balance (CFB) and adverse events within 30 days after OA. The Kaplan–Meier method and the log-rank test were utilized for PFC after OA. A generalized linear regression model for the time to PFC and CFB was built.

Results
A total of 134 patients completed the trial (BIA, n = 66; TRD, n = 68). The BIA patients were significantly more likely to achieve PFC than the TRD patients (83.33% vs. 55.88%, P < 0.001). In the BIA group, the time to PFC occurred earlier than that of the TRD group by an average of 3.66 days (P < 0.001). Additionally, the BIA group showed a lower postoperative 7-day CFB by an average of 6632.80 ml (P < 0.001) and fewer complications.

Conclusion
Among postinjury OA patients in the ICU, the use of BIA-guided fluid resuscitation resulted in a higher PFC rate and fewer severe complications than the traditional fluid resuscitation strategy.
3D Biomechanics of Rugby Tackle Techniques to Inform Future Rugby Research Practice: a Systematic Review
Authors: Edwards Suzi , Lee Roger , Fuller Gordon , Buchanan Matthew , Tahu Timana , Tucker Ross , Gardner Andrew J. 
Published: June 2021

Abstract
Background
The tackle is the most common in-play event in rugby union and rugby league (the rugby codes). It is also associated with the greatest propensity for injury and thus accounts for the most injuries in the sport. It is therefore of critical importance to accurately quantify how tackle technique alters injury risk using gold-standard methodology of three-dimensional motion (3D) capture.

Objective
To examine the 3D motion capture methodology of rugby-style tackle techniques to provide recommendations to inform practice for future rugby code research and advance the knowledge of this field.

Study Design
Systematic review.

Methods
Articles published in English language, up to May 2020, were retrieved via nine online databases. All cross-sectional, correlational, observational, and cohort study designs using 3D motion capture of tackle techniques in rugby code players met inclusion criteria for this review. A qualitative synthesis using thematic analysis was pre-specified to identify five key themes.

Results
Seven articles met eligibility criteria. Participant demographic information (theme one) involved a total of 92 rugby union players, ranging in skill level and playing experience. Experimental task design information (theme two) included one-on-one, front-on (n=5) or side-on (n=1) contact between a tackler and a ball carrier, or a tackler impacting a tackle bag or bump pad (n=3). 3D data collection (theme three) reported differing sampling frequencies and marker sets. 3D data reduction and analysis (theme four) procedures could be mostly replicated, but the definitions of temporal events, joint modelling and filtering varied between studies. Findings of the studies (theme five) showed that the one-on-one tackle technique can be altered (n=5) when tackle height, leg drive and/or tackle speed is modified. A study reported tackle coaching intervention.

Conclusions
This is the first review to evaluate 3D motion capture of rugby-style tackle technique research. A research framework was identified: (i) participant demographic information, (ii) experimental task design information, (iii) 3D motion capture data specifications, and (iv) 3D data reduction and analysis. Adherence of future 3D tackling research to these framework principles will provide critical scientific evidence to better inform injury reduction and performance practices in the rugby codes.

Trial Registration
The review was registered with PROSPERO (registration number CRD42018092312).
Diosgenin and galactomannans, natural products in the pharmaceutical sciences
Authors: Shahrajabian Mohamad Hesam , Sun Wenli , Marmitt Diorge Jonatas , Cheng Qi 
Published: June 2021

Abstract
Background
Diosgenin is an isospirostane derivative, which is a steroidal sapogenin and the product of acids or enzymes hydrolysis process of dioscin and protodioscin. Galactomannans are heteropolysaccharides composed of D-mannose and D-galactose, which are major sources of locust bean, guar, tara and fenugreek.

Methods
Literature survey was accomplished using multiple databases including PubMed, Science Direct, ISI web of knowledge and Google Scholar.

Results
Four major sources of seed galactomannans are locust bean (Ceratonia siliqua), guar (Cyamopsis tetragonoloba), tara (Caesalpinia spinosa Kuntze), and fenugreek (T.foenum-graecum). Diosgenin has effect on immune system, lipid system, inflammatory and reproductive systems, caner, metabolic process, blood system, blood glucose and calcium regulation. The most important pharmacological benefits of galactomannan are antidiabetic, antioxidant, anticancer, anticholinesterase, antiviral activities, and appropriate for dengue virus and gastric diseases.

Conclusions
Considering the importance of diosgenin and galactomannans, the obtained findings suggest potential of diosgenin and galactomannans as natural products in pharmaceutical industries.
Correlation of periodontal diseases with intracranial aneurysm formation: novel predictive indicators
Authors: Liu Keyun , Sun Jia , Shao Lingling , He Hongwei , Liu Qinglin , Li Youxiang , Ge Huijian 
Published: June 2021

Abstract
Background
We investigated whether periodontal diseases, specifically, periodontitis and gingivitis, could be risk factors of the incidence of intracranial aneurysms (IAs).

Methods
We performed a case–control study to compare the differences in the periodontal disease parameters of 281 cases that were divided into the IAs group and non-IAs group. All cases underwent complete radiographic examination for IAs and examination for periodontal health.

Results
Comparing with those in the non-IAs group, the cases in the IAs group were older (53.95 ± 8.56 vs 47.79 ± 12.33, p < 0.001) and had a higher incidence of hypertension (76 vs 34, p = 0.006). Univariate logistic regression analysis revealed that age (> 50 years) and hypertension were predictive risk factors of aneurysm formation (odds ratio [OR] 1.047, 95% confidence interval [95% CI] 1.022–1.073, p < 0.001 and OR 2.047, 95% CI 1.232–3.401, p = 0.006). In addition, univariate and multivariate logistic regression analyses showed that the parameters of periodontal diseases, including gingival index, plaque index, clinical attachment loss, and alveolar bone loss, were significantly associated with the occurrence of IAs (all p < 0.05). For further statistical investigation, the parameters of periodontal diseases were divided into four layers based on the quartered data. Poorer periodontal health condition (especially gingival index > 1.1 and plaque index > 1.5) had the correlation with IAs formation (p = 0.007 and p < 0.001).

Conclusion
Severe gingivitis or periodontitis, combining with hypertension, is significantly associated with the incidence of IAs.
The context of presenting “others”: the construction of meaning and the potential of communication in ethnographic film
Authors: Xiong Xun , Li Jing 
Published: June 2021

AbstractHow can images be used as an expressive, yet clearly limited, tool to represent “the other” in ethnographic films? Based on the objectives of visual anthropology and visual communication, this article analyzes the four presentational traditions of meaning construction. These traditions have been incorporated into the audio-visual communication context to illustrate the similarities or differences between ethnographic films and ethnographic texts in terms of traditions, structures, features, and limitations. Through the analysis of the four traditions, the relationships between visual presentation and text writing, visual patterns and communication concepts, and visual potentials and ethnographic films have been fully examined. In the context of Chinese ethnographic films, the four presentational traditions have been well showcased and developed. These works, in their different contexts, have constituted a meaningful visual text system of contemporary Chinese anthropology.
3D Printed frames to enable reuse and improve the fit of N95 and KN95 respirators
Authors: McAvoy Malia , Bui Ai-Tram N. , Hansen Christopher , Plana Deborah , Said Jordan T. , Yu Zizi , Yang Helen , Freake Jacob , Van Christopher , Krikorian David , Cramer Avilash , Smith Leanne , Jiang Liwei , Lee Karen J. , Li Sara J. , Beller Brandon , Huggins Kimberley , Short Michael P. , Yu Sherry H. , Mostaghimi Arash , Sorger Peter K. , LeBoeuf Nicole R. 
Published: June 2021

Abstract
Background
In response to supply shortages caused by the COVID-19 pandemic, N95 filtering facepiece respirators (FFRs or “masks”), which are typically single-use devices in healthcare settings, are routinely being used for prolonged periods and in some cases decontaminated under “reuse” and “extended use” policies. However, the reusability of N95 masks is limited by degradation of fit. Possible substitutes, such as KN95 masks meeting Chinese standards, frequently fail fit testing even when new. The purpose of this study was to develop an inexpensive frame for damaged and poorly fitting masks using readily available materials and 3D printing.

Results
An iterative design process yielded a mask frame consisting of two 3D printed side pieces, malleable wire links that users press against their face, and cut lengths of elastic material that go around the head to hold the frame and mask in place. Volunteers (n = 45; average BMI = 25.4), underwent qualitative fit testing with and without mask frames wearing one or more of four different brands of FFRs conforming to US N95 or Chinese KN95 standards. Masks passed qualitative fit testing in the absence of a frame at rates varying from 48 to 94 % (depending on mask model). For individuals who underwent testing using respirators with broken or defective straps, 80–100 % (average 85 %) passed fit testing with mask frames. Among individuals who failed fit testing with a KN95, ~ 50 % passed testing by using a frame.

Conclusions
Our study suggests that mask frames can prolong the lifespan of N95 and KN95 masks by serving as a substitute for broken or defective bands without adversely affecting fit. Use of frames made it possible for ~ 73 % of the test population to achieve a good fit based on qualitative and quantitative testing criteria, approaching the 85–90 % success rate observed for intact N95 masks. Frames therefore represent a simple and inexpensive way of expanding access to PPE and extending their useful life. For clinicians and institutions interested in mask frames, designs and specifications are provided without restriction for use or modification. To ensure adequate performance in clinical settings, fit testing with user-specific masks and PanFab frames is required.