bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perception and Initial Adoption of Mobile Health Services of Older Adults in London: Mixed Methods Investigation
Authors: Pan Jing , Dong Hua , Bryan-Kinns Nick 
Published: November 2021

Background
Advances in mobile technology and public needs have resulted in the emergence of mobile health (mHealth) services. Despite the potential benefits of mHealth apps, older adults face challenges and barriers in adopting them.

Objective
The aims of this study are to understand older adults’ perception of mHealth services and to discover the barriers that older adults face in the initial adoption of mHealth apps.

Methods
This paper systematically analyzed main determinants related to mHealth services and investigated them through questionnaires, interviews, and a workshop. Two studies were carried out in London. In study 1, the questionnaires with follow-up interviews were conducted based on the literature review to uncover older adults’ perception (including perceived usefulness, perceived ease of use, and perceived behavioral control) of mHealth services. Study 2 was a workshop helping older adults to trial selected mHealth apps. The workshop was conducted by the first author (JP) with assistance from 5 research students. The barriers that older adults faced in the initial adoption period were observed. The interviews and workshop were audiotaped and transcribed. Descriptive statistics and the thematic analysis technique were used for data analysis.

Results
In total, 30 older adults in London completed the questionnaires and interviews in study 1. The results of study 1 show that the lack of obvious advantage, low reliability, scary information, and the risk of privacy leakage would decrease older adults’ perceived usefulness of mHealth services; the design of app interface would directly affect the perceived ease of use; and aging factors, especially the generation gap, would create barriers for older users. In total, 12 participants took part in the workshop of study 2, including 8 who took part in study 1. The results of study 2 identified that access to technology, the way of interaction, the risk of money loss, heavy workload of using an mHealth app, and different lifestyle are influential factors to older adults’ adoption of mHealth services.

Conclusions
The perceptions of mHealth services of older adults were investigated; the barriers that older adults may face in the initial adoption stage were identified. On the basis of the synthesis of these results, design suggestions were proposed, including technical improvement, free trial, information clarification, and participatory design. They will help inform the design of mHealth services to benefit older adults.
mHealth Solutions for Perinatal Mental Health: Scoping Review and Appraisal Following the mHealth Index and Navigation Database Framework
Authors: Spadaro Benedetta , Martin-Key Nayra A , Funnell Erin , Bahn Sabine 
Published: November 2021

Background
The ever-increasing pressure on health care systems has resulted in the underrecognition of perinatal mental disorders. Digital mental health tools such as apps could provide an option for accessible perinatal mental health screening and assessment. However, there is a lack of information regarding the availability and features of perinatal app options.

Objective
This study aims to evaluate the current state of diagnostic and screening apps for perinatal mental health available on the Google Play Store (Android) and Apple App Store (iOS) and to review their features following the mHealth Index and Navigation Database framework.

Methods
Following a scoping review approach, the Apple App Store and Google Play Store were systematically searched to identify perinatal mental health assessment apps. A total of 14 apps that met the inclusion criteria were downloaded and reviewed in a standardized manner using the mHealth Index and Navigation Database framework. The framework comprised 107 questions, allowing for a comprehensive assessment of app origin, functionality, engagement features, security, and clinical use.

Results
Most apps were developed by for-profit companies (n=10), followed by private individuals (n=2) and trusted health care companies (n=2). Out of the 14 apps, 3 were available only on Android devices, 4 were available only on iOS devices, and 7 were available on both platforms. Approximately one-third of the apps (n=5) had been updated within the last 180 days. A total of 12 apps offered the Edinburgh Postnatal Depression Scale in its original version or in rephrased versions. Engagement, input, and output features included reminder notifications, connections to therapists, and free writing features. A total of 6 apps offered psychoeducational information and references. Privacy policies were available for 11 of the 14 apps, with a median Flesch-Kincaid reading grade level of 12.3. One app claimed to be compliant with the Health Insurance Portability and Accountability Act standards and 2 apps claimed to be compliant with General Data Protection Regulation. Of the apps that could be accessed in full (n=10), all appeared to fulfill the claims stated in their description. Only 1 app referenced a relevant peer-reviewed study. All the apps provided a warning for use, highlighting that the mental health assessment result should not be interpreted as a diagnosis or as a substitute for medical care. Only 3 apps allowed users to export or email their mental health test results.

Conclusions
These results indicate that there are opportunities to improve perinatal mental health assessment apps. To this end, we recommend focusing on the development and validation of more comprehensive assessment tools, ensuring data protection and safety features are adequate for the intended app use, and improving data sharing features between users and health care professionals for timely support.
RECENT ADVANCES INPHARMACOTHERAPY OF ALZHEIMER’S DISEASE
Authors: NARWAT ARVIND , SHARMA VIVEK , KUMAR SUNEEL , RANI SEEMA 
Published: November 2021

The management of Alzheimer's disease (AD) has been a long-standing challenge and area of interest. Advances in knowledge of the pathogenesis of disease and an increase in disease burden have prompted investigation into innovative therapeutics over the last two decades. Current approved therapies are symptomatic treatments having some effect on cognitive function. Therapies that target β-amyloid (Aβ) have been the focus of efforts to develop a disease modification treatment for AD but these approaches have failed to show any clinical benefit so far. Beyond the 'Aβ hypothesis', there are a number of newer approaches to treat AD. This short review will summarize approved drug therapies, recent clinical trials and new approaches for the treatment of AD.
FORMULATION AND EVALUATION OF MASLINIC ACID LOADED TRANSDERMAL PATCHES
Authors: CHOUDHORY NEHA , KAUR TARANJIT , SINGH AJEET PAL , SINGH AMAR PAL 
Published: November 2021

Objective: To develop and evaluate Transdermal patch of Maslinic acid for Transdermal drug delivery. The current study is to develop Transdermal drug delivery system.
Methods: Suitable method such as Solvent Casting Technique of Film Casting Technique are used for preparation of Transdermal patch.
Results: The prepared Transdermal patches were transparent, smooth, uniform and flexible. The method adopted for the preparation of the system was found satisfactory.
Conclusion: Various formulations were developed by using hydrophilic and hydrophobic polymers like HPMC E5 and EC respectively in single and combinations by solvent evaporation technique with the incorporation of penetration enhancer such as dimethylsulfoxide and dibutyl phthalate as plasticizer In vitro studies concluded that HPMC E5 patches has better release than that of EC patches, which may be attributed to high water vapour permeability of HPMC patches and hydrophobic nature of EC. An attempt was made to incorporate HPMC E5 and EC to the monolithic system for better release and prolong the duration of release. Formulation F7 containing an equal ratio of HPMC E5: EC (5:5) showed maximum and sustained release of 86.816±0.264 within 24 h. Kinetic models were used to confirm the release mechanism of the formulations. Maslinic acid release from the patches F1 to F7 followed non Fickian diffusion rate controlled mechanism.
Efek Spasial Jaringan Jalan di Kota Jambi
Authors: Harmes Harmes , Zuhdi Mohammad , Naswir Muhammad 
Published: November 2021

Substansi pembangunan berbasis spasial di Indonesia diregulasikan melalui kebijakan penataan ruang, tujuannya adalah menata aspek struktur dan pola ruang wilayah. Struktur ruang fokus pada jaringan infrastruktur sedangkan pola ruang mengatur penggunaan lahan. Kebijakan ini diimplemetasikan secara massif sejak tahun 2007, namun efek spasial setiap aspeknya belum banyak diteliti. Hal ini menyebabkan Rencana Tata Ruang Wilayah propinsi dan kabupaten/kota diimplementasikan cenderung tidak dilengkapi dengan kedalaman analisis yang kuat untuk mendukung pengaturan struktur dan pola ruang wilayah. Kajian ini bertujuan menelaah aspek struktur ruang yakni jaringan jalan sebagai indikator aksessibilitas wilayah sebagai bentuk output pembangunan yang berdampak luas pada kemajuan wilayah. Fokus penelitian adalah efek spasial jaringan jalan yang diukur dari panjang jalan dan keterkaitannya dengan variabel dirinya secara kontinyu dan berketetanggaan dengan wilayah sekitarnya. Unit amatan meliputi seluruh kecamatan di Kota Jambi. Statistik yang digunakan adalah indeks moran, selanjutnya untuk penyelidikan lokalitas autokorelasi spasial diidentifikasi melalui statistik spasial local idenfitification of spatial autocorrelation (LISA). Hasil penelitian menunjukkan bahwa jaringan jalan tidak memiliki autokorelasi spasial yang kuat atau termasuk kategori random dengan nilai indeks moran sebesar 0.149. Identifikasi lebih lanjut dengan LISA menunjukkan adanya autokorelasi spasial pada tingkat signifikan 0.05. Efek spasial lokal jaringan jalan terjadi pada kecamatan Kota Baru dan Jambi Selatan. Pola spasial yang acak pada aspek jaringan wilayah ini menunjukkan adanya heterogenitas antara satu kecamatan dengan lainnya, sehingga kebijakan pembangunan jalan tidak boleh disamakan secara menyeluruh, namun harus memperhatikan diferensiasi yang terjadi.
Association of Bariatric Surgery With Cancer Incidence in Patients With Obesity and Diabetes: Long-term Results From the Swedish Obese Subjects Study
Authors: Sjöholm Kajsa , Carlsson Lena M.S. , Svensson Per-Arne , Andersson-Assarsson Johanna C. , Kristensson Felipe , Jacobson Peter , Peltonen Markku , Taube Magdalena 
Published: November 2021

OBJECTIVE
Obesity and type 2 diabetes are associated with serious adverse health effects, including cancer. Although bariatric surgery has been shown to reduce cancer risk in patients with obesity, the effect of bariatric surgery on cancer risk in patients with obesity and diabetes is less studied. We therefore examined the long-term incidence of cancer after bariatric surgery and usual care in patients with obesity and diabetes in the matched prospective Swedish Obese Subjects (SOS) study.

RESEARCH DESIGN AND METHODS
The SOS study examines long-term outcomes following bariatric surgery or usual care. The current analysis includes 701 patients with obesity and type 2 diabetes at baseline, 393 of whom underwent bariatric surgery and 308 who received conventional obesity treatment. Information on cancer events was obtained from the Swedish National Cancer Register. Median follow-up time was 21.3 years (interquartile range 17.6–24.8 years, maximum 30.7 years).

RESULTS
During follow-up, the incidence rate for first-time cancer was 9.1 per 1,000 person-years (95% CI 7.2–11.5) in patients with obesity and diabetes treated with bariatric surgery and 14.1 per 1,000 person-years (95% CI 11.2–17.7) in patients treated with usual obesity care (adjusted hazard ratio 0.63 [95% CI 0.44–0.89], P = 0.008). Moreover, surgery was associated with reduced cancer incidence in women (0.58 [0.38–0.90], P = 0.016), although the sex-treatment interaction was nonsignificant (P = 0.630). In addition, diabetes remission at the 10-year follow-up was associated with reduced cancer incidence (0.40 [0.22–0.74], P = 0.003).

CONCLUSIONS
These results suggest that bariatric surgery prevents cancer in patients with obesity and diabetes and that durable diabetes remission is associated with reduced cancer risk.
SELF-REFERENCE, THEORY OF TYPES, AND CATEGORIZATION IN WITTGENSTEIN’S PICTURE THEORY OF STATEMENTS
Authors: Суровцев Валерий Александрович 
Published: November 2021

Рассматривается источник логических парадоксов, выявленных Б. Расселом в системе обоснования математики, предложенной Г. Фреге. Самореферентность выражений, предложенная Б. Расселом как объяснение возникновения парадоксов, рассматривается с точки зрения разработанной им простой и разветвленной теории типов. Обосновывается, что теория типов, предложенная Б. Расселом, основана на онтологических предпосылках. Онтологические предпосылки зависят от предпочтения семантическому перед синтаксическим подходом, который принимается Б. Расселом. Рассмотрены синтаксические подходы к логическому символизму, которые позволяют устранить парадоксы с точки зрения языка современной символической логики. Анализируется подход к решению парадоксов Л. Витгенштейна, который основан на синтаксическом подходе. Показано, что этот подход отличается от способов построения языка, принятых в современной логике.The article analyzes the source of logical paradoxes Bertrand Russell identified in the foundations of mathematics proposed by Gottlob Frege. Russell proposed self-reference of expressions as the source of paradoxes. To solve paradoxes, he developed the simple and ramified theory of types. Ontological presuppositions are well substantiated for his theory; they depend on semantic, but not syntactic, preference. Contemporary approaches in symbolical logic prefer syntactic methods. But Wittgenstein’s approach in his Tractatus Logico-Philosophicus is more interesting, especially from the perspective of his picture theory of statements.
Law School Learning Outcomes: Legal English Course Contribution
Authors: Vyushkina Elena 
Published: November 2021

Abstract
Standards of professional legal education are developed by different organizations: in some countries these are governmental bodies, in others these are professional associations. Apart from a country these standards include Learning Outcomes which shape law schools’ curricula. Both American and European standards mention, to different extent, written and oral communication in the legal context, but a number and contents of subjects directed at developing and mastering professional communicative competency differ a lot. There are disciplines totally devoted to the competency named (e.g. legal writing) as well as courses in which communicative skills are an integral constituent for their successful completion (e.g. basis of negotiations/mediation/client consultation).
The article goal is to find a place and role of a Legal English (LE) course in achieving learning outcomes connected with professional communicative competence. The methodology incorporated desk and field studies. The literature review is aimed at identifying current state of affairs in American law schools, as they provide first-class legal education recognized all over the world, and in Russian law schools, as the author works in this system and is interested in its development. A questionnaire was designed to explore Russian law school graduates’ assessment of practicality of subjects they had studied for their professional activities.
The analysis of literature and Internet sources allowed to specify the ways of teaching written and oral communication in American law schools and to highlight the situation in Russian legal education. It shows that the Russian system is characterized by predominance of teaching theory of substantive and procedural rules of law and lack of curriculum disciplines aimed at cultivating skills and competencies.
A survey of Russian law schools’ recent graduates indicates that most of communicative, in a broad sense, skills, which they use in their everyday work, were obtained within their LE classes. So, complementing a LE course with modules devoted to different aspects of legal writing and specific patterns of lawyer-client, lawyer-lawyer, lawyer-judge communication will definitely contribute to achieving learning outcomes which are put forward by legal education standards.
Yugan Khanty Phonetic Features Based on the Experimental Data
Authors: Timkin Timofey V. 
Published: November 2021

The paper deals with the phonetics of Yugan idiom of Surgut Khanty. The research is a part of the project aimed at describing Surgut Khanty phonetics. The Yugan idiom has significant differences from the Tromyegan idiom described before.
The analysis is based on the data collected during the expedition to the settlement Ugut in 2019. The experimental part includes 130 words list read out three times by four native speakers from different traditional settlements on the Malyi Yugan river and on the Bolshoi Yugan river.
The research was conducted using experimental techniques: Praat, Emu-SDMS software. The main technique was a formant analysis that deals with resonant frequencies in vowel spectra to obtain data on articulation features. Statistical evaluations and visualization were established via R programming language.
We found differences between the Malyi Yugan river and the Bol’shoi Yugan river idioms. 12 vowel phonemes were found in the Malyi Yugan idiom. Compared to the Tromyegan system the phoneme /ɔ/ (traditionally /ȯ̆/) is absent. It was replaced by /ɛ/ (traditionally /ȧ̆/) or /o/ (traditionally /ŏ/). The phoneme u̇ described in previous literature on the topic disappeared and was replaced by /iː/.
The Bolshoi Yugan vowel system includes these phonemes and also diphthongs [ui], [ɔɛ]. They appear after [k] where etimological u̇, ȯ̆ used to be. They probably are the realizations of the phonemes /iː/, /ɛ/ in the position after labialized k, which has become a phoneme.
Non-initial [w] is reported to be specific Jugan feature and appears to have parallels in Tromyegan idiom too. It is an evidence for the rearranging of the Surgut idioms. In this pronunciation type /w/ is realized as a labial approximant in an initial position and after not-rounded vowels in a non-final position. After not-rounded vowels in a final position it comes as an initial-voiced fricative evoking preceding vowel diphthongization. After rounded vowels it is labiovelar [γʷ] or non-syllabic [ʊ] (before consonants). This pronunciation type is similar to the Tromyegan type, but it differs from the Pim type where /w/ comes as a labial approximant consistently.
The disappearance of labial fricatives is a new phenomenon which has not been described properly. Territorial and social factors for this process are given. The Malyi Yugan speakers use lateral fricatives /ł/, /ʎ̥/ and the Bolshoi Yugan speakers replace it by /t/, /c͡c̦/. In the settlement Ugut where Bolshoi and Malyi Yugan natives contact in Russian-spoken environment both variants are used with t-pronunciation evaluated by speakers as new and declining from the ‘'right’ speech.
Semantic Differences between Verb-Nominal Collocations and Corresponding Verbs (As Exemplified by Collocations with Verbs Ispytyvat’ / Ispytat’)
Authors: Kozlov Ivan M. , Kuznetsova Elena S. 
Published: November 2021

The following article focuses on semantical differences of verbal-nominal descriptive predicates constructed by verbs ispytyvat’ / ispytat’ from their lexically adequate verbal correlates. The Russian linguistic tradition describes such collocations as verbal periphrasis, and this leads to a misjudgment of their semantical particularity. Our main goal is to describe the differences due to state semantical independence of the collocations from the verbs.
The study showed that an emotional state described by descriptive predicates with verbs ispytyvat’ / ispytat’ presupposes no explication, which differs them from some lexically adequate verbal correlates. It reveals an intra-subject nature of their semantics that can be manifested in a specific actant structure or in its implementation. It is also worth noting their semantic complexity and an important role of verbal component: different meanings of the verbal component cause different semantics of whole collocation even with the same nominal one. Thus, particular meaning of a nominal component and of a verbal one makes up semantics of a whole construction.
Many types and examples of semantical discrepancy between the verbal-nominal descriptive predicates and their lexically adequate verbal correlates leads to the necessity of describing their semantics departed from the verbal correlates’ meaning and of the refusal to consider them as means of verbal periphrasis.
Metodologias ativas no ensino de gestão em saúde no curso de medicina: o olhar discente
Authors: Brito Felipe Gabriel Silva , Viana Antonia Iracilda e Silva , Sirqueira Bruna Pereira Carvalho , Sousa Jacyane Ramos de , Oliveira Maricélia Tavares Borges , Martins Danyelle Silva 
Published: November 2021

Objetivo: Analisar, a partir da perspectiva do discente o ensino da disciplina gestão em saúde através de metodologias ativas em um curso de medicina na região sul do Maranhão. Métodos: Estudo observacional, transversal e retrospectivo com 54 alunos do último ano do curso de medicina. Foi utilizado um questionário com perguntas agrupadas em domínios: objetivos da disciplina, metodologia utilizada, identificação de problemas no sistema de saúde, formação médica, estrutura física dos cenários de prática e autoavaliação do discente. Os dados obtidos foram analisados através do software R (R Core Team, 2019) versão 3.5.3. O estudo foi aprovado pelo Comitê de Ética em Pesquisa. Resultados: 83,3% possuem de 20 a 29 anos; 55,6% cor branca; 55,6% sexo feminino. Correlacionando-se a autoavaliação do aluno com aspectos da metodologia da disciplina houve significância estatística nos aspectos: objetivos da disciplina foram informados (p <0,001), objetivos da disciplina foram alcançados (p <0,001), conteúdos da disciplina foram satisfatórios (p = 0,027), passou a conhecer um SUS que até então desconhecia (p = 0,0042). Conclusão: A utilização de metodologias ativas proposta pelas mudanças nas diretrizes curriculares resultou em um processo de aprendizado mais dinâmico e crítico.