bluuebunny/crossref_metadata_2025_split huggingface dataset:
Editorial del Vol. 1 No. 1
Authors: Veliz Briones Vicente 
Published: December 2021

A pesar del control de la natalidad, el aumento poblacional mundial es eminente; consultando datos oficiales de la Naciones Unidas vemos que en el último medio siglo se ha quintuplicado, y se espera llegar en el año 2075 a los 10.000 millones de habitantes (un mundo en población más, igual al que existía en 1987). Independientemente, de los avatares demográficos, e inclusive de la capacidad de carga del planeta, la visión que debemos tener es como, entre otras cosas, podemos alimentar a ese masa poblacional humana, teniendo en cuenta que es nuestra responsabilidad como países iberoamericanos, ya que el crecimiento poblacional proviene, en su mayoría, de países en vías de desarrollo. No obstante, no es solo una cuestión de números totales, sino de la calidad de nuestras poblaciones, ya que, hoy en día, de los 7.750 millones de personas, se estima la existencia con casi 1000 millones de personas desnutridas, y 1700 millones malnutridas, lo cual hace imperativo y de responsabilidad histórica la producción de alimentos pero nutritivos y sanos, como los productos acuícolas los cuales son señalados como unos de los más importantes para palear la alta demanda poblacional; sin embargo, nuestros cuerpos de agua sean continentales o marinos sufren, en la mayoría, intervenciones que hacen que la pesca no pueda subsanar las demandas, siendo la acuicultura parte de la solución, la cual hoy suple más de la mitad de la producción acuícola.
Efecto de probióticos sobre el crecimiento de semillas de ostión del pacífico Crassostrea gigas
Authors: García Bernal Milagro , Medina Marrero Ricardo , Campa Córdoba Ángel Isidro , Barajas Frías José Delfino , Luis Villaseñor Irasema Elizabeth , Mazón Suástegui José Manuel 
Published: December 2021

Se realizó un estudio en juveniles de Crassostrea gigas para investigar el potencial efecto probiótico de Streptomyces spp. (cepas V4, N7 y RL8) y de una mezcla de Bacillus (BMix) teniendo como variable de respuesta su crecimiento. Las bacterias fueron adicionadas con el alimento vivo (microalgas), para ser ingeridas por los ostiones mediante filtración. El diseño experimental incluyó cuatro tratamientos bacterianos: [T1 (Streptomyces sp. V4); T2 (Streptomyces sp. N7); T3 (Streptomyces sp. RL8); T4, una mezcla de bacilos BMix (Bacillus tequilensis YC5-2, Bacillus endophyticus C2-2 y Bacillus endophyticus YC3-B] y un tratamiento Control (T5) con solo microalgas como alimento. Estas cepas potencialmente probióticas fueron suministradas a una concentración final de 1 × 106 UFC mL-1 y las microalgas (Isochrysis galbana y Chaetoceros calcitrans en proporción 1:1) a una densidad de 70-80 × 103 células mL-1). Los tratamientos T1 y T3 (Streptomyces spp. V4 y RL8, respectivamente), incrementaron significativamente el área y el diámetro teórico de la concha de C. gigas. Esto sugiere que la adición Strepromyces spp. V4 y RL8 puede mejorar el crecimiento de C. gigas durante el proceso de preengorda de semillas en laboratorio.
Effect of hydrogen sulfide on the characteristics of the neuromuscular synapse terminals of the rat diaphragm
Authors: Kadenov A.N. , Yakovleva O.V. 
Published: December 2021

Hydrogen sulfide is one of the gas-transmitters that also performs other biological functions. The antioxidant property of this substance is one of the important ones. The research was conducted on rats of both sexes between 6 and 18 days of age. We have shown that the offspring of females injected subcutaneously with hydrogen sulfide increased the area and luminescence of nerve terminals during postnatal ontogenesis, which can be further used to level the effects of hyperhomocysteinemia on synaptic transmission.
Key words: neuromuscular synapse, fluorescent microscopy, hydrogen sulfide.
The role of disorders in the functional activity of platelets in the pathogenesis of microcirculatory disorders in patients with catarrhal gingivitis
Authors: Kitaeva V.N. , Smolkina A.V. 
Published: December 2021

A comprehensive examination of patients with chronic catarrhal gingivitis and with exacerbation of chronic catarrhal gingivitis with the inclusion of indicators of the microcirculatory link of the hemostasis system was carried out. In patients with exacerbation of chronic catarrhal gingivitis, platelet aggregation activity is increased compared to that in healthy individuals. This is accompanied by a statistically significant increase in the maximum degree of aggregation, a change in the time to reach the maximum degree of platelet aggregation
Key words: platelet aggregation, catarrhal gingivitis, exacerbation of chronic catarrhal gingivitis.
The role of neuronal NO synthase in the respiratory effects of TNF-α
Authors: Klinnikova A.A. , Danilova G.A. , Aleksandrova N.P. 
Published: December 2021

It was shown that an increase level of proinflammatory cytokines has a modulating effect on the reflex control of respiration. The aim of this study was to investigate the involvement of neuronal nitric oxide synthase (nNOS) in the mechanisms of the influence of an increased level of Tumor necrosis factor – α (TNF-α) on the hypoxic ventilatory response. To achieve this goal, experiments were carried out on urethane anesthetized rats with intravenous administration of TNF-α before and after pretreatment with 7-nitroindazole specific nNOS inhibitor. The hypoxic ventilation response was assessed by rebreathing with a hypoxic gas mixture before and after administration of TNF-α. We found that TNF-α decreased the ventilatory response to hypoxia. Pretreatment with nNOS inhibitor reduced respiratory effects of TNF-α.
Key words: cytokines, TNF-α, hypoxia, chemoreflex, respiration, ventilation, neuronal nitric oxide synthase.
Modern problems of regionalization of territories and human adaptation in regions with extreme natural and climatic conditions
Authors: Maksimov A.L. 
Published: December 2021

The paper considers modern approaches to the zoning of territories and the selection of people for life in extreme environmental conditions, taking into account modern geopolitical challenges. It is shown that it is possible, based on the allostasis concept, to conduct not only the selection of persons with a high level of nonspecific resistance, but also to quantify the degree of extremity of environmental factors using the standard represpiration test.
Key words: adaptation, extreme conditions, selection, hypoxia, cold, rerespiration, allostatic load.
Quality of life of patients after inguinal hernioplasty by endoscopic methods
Authors: Asutaev Sh.D. , Poborskiy A.N. 
Published: December 2021

A comparative analysis of the indicators of 53 men who underwent inguinal hernioplasty using the TEP (n = 20) and TAPP (n = 33) methods was carried out. Quality of life was assessed using the international questionnaire EQ-5D on the 1st day, 1 month and 12 months after surgery. Monitoring of quality of life parameters showed differences in the assessment of their condition by patients who underwent TEP and TAPP, which were most pronounced on the first day after surgery. The presence of problems during this period for all components of the EQ-5D questionnaire, to a greater extent, was associated by patients with pain / discomfort in the operation area. The latter were maximally manifested in the majority of those who underwent TAPP (64%), which also affected their lower assessment of their health status. The revealed differences disappear within a month after the interventions and are absent 12 months after the operation.
Key words: quality of life, inguinal hernioplasty, endoscopic methods.
Assessment of the functional state of military men with different types of autonomic regulation in the midland’s conditions
Authors: Satarkulova A.M. , Melisova B.M. , Aisaeva Sh.Yu. 
Published: December 2021

The article presents the results of assessment and dynamic control over the functional state of military men in the midlands conditions. Depending on the initial type of autonomic regulation, groups with vagotonic (24%), sympatotonic (26%) and normotonic (50%) directions of regulatory processes were identified. It has been established that the state of optimal working voltage with more economical functioning of regulatory mechanisms is characteristic of carriages; for sympathotonics - an overstrain of regulatory mechanisms, and for normotonics - a moderate tension of regulatory systems with the mobilization of the functional reserves of the body.
Key words: heart rate variability, functional state, types of autonomic regulation, midlands, military men.
Vascular-tissue relations in the lungs in experimental superinvasive opisthorchiasis
Authors: Shvedsky M.S. , Solovyov G.S. , Matvienko V.V. , Shidin V.A. , Solovyova O.G. , Istomina O.F. 
Published: December 2021

Structural changes in the lungs in superinvasive opisthorchiasis at various stages of invasion were studied. The morphology of permanent epithelial proliferation at the initial stage and their decrease in the late period were revealed. With the formation of granulomas in the interstitial tissue of the respiratory organs, with changes in the chronic period towards the formation of sclerotic foci.
Key words: superinvasive opisthorchiasis (CO), metacercariae, acinus, terminal bronchioles (TB), cell infiltrates, pneumocytes.
Comparative characteristics of the main sanogenetic mechanisms in large laboratory animals (pigs) with acute blood loss and after infusion of an isotonic colloidal solution based on dextran and an isotonic solution based on polyglucin in conditions of general external cooling
Authors: Shvetc A.O. , Shperling I.A. , Krupin A.V. , Romanov P.A. , Matveeva N.N. 
Published: December 2021

The experiment was carried out on male pigs, which in the operating room were simulated with acute blood loss (air temperature 23oC). Then the animals were placed in a climatic chamber (minus 50 ° C) for 10 minutes. Then the temperature in the climatic chamber was raised to minus 10 ° C and the introduction of the test solutions to the animals began. It was found that in both groups there were similar indicators of blood pressure. The heart rate and respiratory rate in animals in the group with the experimental solution based on polyglucin derivatives were lower than in the group with the solution based on dextran.
Key words: external general cooling, pigs, blood pressure, heart rate, respiratory rate, infusion solution.
he specifics of posture formation among schoolchildren living in the city of Khanty-Mansiysk against the background of undifferentiated connective tissue dysplasia
Authors: Shevnin I.A. , Ragozin O.N. , Ragozina O.V. , Ilyushchenko N.A. , Jafarova B.Z. 
Published: December 2021

Undifferentiated forms of DST are widespread among children living in Khanty-Mansiysk, in connection with which it is relevant to assess the influence of this pathology on the formation of posture in schoolchildren of the North. Determination of the type of posture and the identification of stigmas of dysembryogenesis was carried out in 208 schoolchildren of the city of Khanty-Mansiysk. Posture types were divided into: normal, round, flat and stooped. Participants with the number of stigmas from 0 to 5 were allocated to the comparison group (n = 66), the rest (6 or more) made up the study group (n = 143). A card was entered, including 43 hair dryers. The study found that the incidence of UCTD among children in the Khanty-Mansi Autonomous Okrug-Yugra is noticeably higher than among those living in temperate latitudes and has a negative effect on the formation of posture.
Key words: North, posture, physical development, undifferentiated connective tissue dysplasia.
Temporary cardiointerval organization with varying degrees of acute normobaric hypoxia in a healthy person
Authors: Bocharov M.I. 
Published: December 2021

The influence of acute normobaric hypoxia (ANH) on the male heart chronotropic effects was studied. Thus, a mild degree of ANH (14.5 % O2, 20 min), causing a decrease in blood oxygenation by 6.3 abs. %, accompanied by an initial (by 5 min) decrease in the RR and QT intervals. The average degree of ANH (12.3% O2) leads to a decrease in blood oxygenation by 19.7 abs. %. At the same time, in inverse relationship to the developing hypoxemia, RR and QT significantly decrease. Corrected values (Pc, PQc, QRSc, QTc) increase during the action period of an average degree of hypoxia, indicating an increase in the proportion of atrial contraction time, atrioventricular conduction of excitation and electrical ventricular systole in the total RR duration, which, apparently, provides optimal systolic heart effect.
Key words: human, hypoxia, blood oxygenation, cardiointervals.
External respiration and gas exchange in conditions of maximum load at different levels of the body's aerobic capacity
Authors: Vinogradov S.N. 
Published: December 2021

The study of the characteristics of the reactions of the links of external respiration and gas exchange at various stages of performing a step-increasing load and at maximum load with various aerobic capabilities of the body was carried out. The data obtained indicate that the level of aerobic capabilities of the body determines the characteristics of the reactions of the links of external respiration and gas exchange at various stages of performing a step-increasing load and at maximum load.
Key words: functional reserves of organism, gas transportation system, maximum oxygen consumption, aerobic capacity of organism, gas exchange.
The role of ENOS polymorphism (C774T) in the progression of acute peritonitis and the formation of complications
Authors: Vlasov A.P. , Al-Kubaysi S.S. , Ali Fuad F.A. , Al-Anbari S.T. , Fedotov B.A. 
Published: December 2021

In order to determine the role of ENOS (C774T) gene polymorphism in the progression of acute peritonitis and the formation of complications, a clinical and biochemical study of 40 patients with acute peritonitis was conducted. As a result of the study, it was proved that the early period of acute peritonitis is characterized by the development of endogenous intoxication, intensification of oxidative phenomena, hypercoagulation of the homeostasis system and inhibition of fibrinolysis, and in patients with acute peritonitis, carriers of the pathological TT genotype of the endothelial nitric oxide synthase gene, more pronounced deviations of homeostatic parameters are observed.
Key words: acute peritonitis, genotype, DNA diagnostics, genetic testing of genotypes.
Prognostic value of endotoxicosis criteria in the diagnosis of acute renal injury
Authors: Vlasov A.P. , Ryazantsev V.E. , Muratova T.A. , Volkova M.V. , Stepanov N.Yu. , Mashnin I.V. 
Published: December 2021

In order to find informative statically significant laboratory criteria for endotoxicosis in the diagnosis of acute renal injury, a clinical and biochemical study of 40 patients with acute renal injury developed against the background of renal urological and extrarenal surgical pathology was conducted. The results of the study demonstrate pronounced changes in the mechanisms of antioxidant protection that develop in patients with acute renal injury. Deviations from the initial level of the studied criteria are interrelated with many links of pathogenesis, where one of the central links is ischemia of the renal parenchyma. The progression of endogenous intoxication, taking into account the data obtained, confirmed by a decrease in prooxidant protection contributes to the progression of intrarenal changes, aggravating functional changes in renal and extrarenal injuries.
Key words: significance of endotoxicosis criteria, acute renal injury, endotoxicosis, serum creatinine, glomerular filtration rate.
Study of the energy supply of muscular activity in the Cooper test among sportsmen-gamers according to the individual heart rate response to the load
Authors: Gorbaneva E.P. , Mitsulina M.P. , Ryabchuk Yu.V. 
Published: December 2021

In this study, using the example of the Cooper test, pulse zones were identified in percentage ratio, which allow indirectly judging the contribution of a particular energy supply system for each athlete during cyclic work.
Keywords: Cooper's test, energy supply, athletes-game players, pulse zones, heart rate monitoring, Polar.
The role of prostaglandins in the realization of respiratory effects of TNF-α in case of hypoxia
Authors: Danilova G.А. , Klinnikova A.A. , Aleksandrova N.P. 
Published: December 2021

At the present time very little is known about interactions between systemic inflammation and control of respiration. The aim of this study was to compare the respiratory effects of the main inflammatory cytokine TNF - α before and after pretreatment with diclofenac, a nonspecific cyclooxygenase (COX) inhibitor.
In experiments on anesthetized, tracheostomized rats, pneumotachometry method was used to measure peak airflow and respiratory rate. The ventilatory response to hypoxia was investigated by the rebreathing method. It is shown that an increase in the systemic level of TNF – α causes a significant increase in the minute volume of respiration, tidal volume, the average speed of the inspiratory flow. In contrast the slope of the hypoxic ventilatory response decreased after administration of TNF-α. Diclofenac pretreatment eliminated these respiratory effects of TNF - α. The data indicate that the ability of TNF - α to enhance basal ventilation and to reduce the ventilatory hypoxic response is mediated by the cyclooxygenase pathway.
Key words: tumor necrosis factor – α, hypoxia, prostaglandins, peripheral chemoreception, respiration.
Forecasting the radiation background in the territories of Kazakhstan located near the uranium mining industries
Authors: Ismailova A.A. , Nurbaeva N.A. 
Published: December 2021

A significant part of the territory of Kazakhstan is characterized by a high natural background radiation of soils and rocks, the spread of natural ground and underground waters with high concentrations of radionuclides in the regions of uranium, thorium and rare metal ore provinces and regions. Therefore, conducting high-quality radio monitoring of the state of the environment using modern information systems will make it possible to predict the background radiation in a timely manner and outline measures to reduce environmental risks to the health of the nation as a whole.
Key words: radioecology, monitoring, life safety, radionuclides, national health.
Junction size dependence of the heat controlled magnetic anisotropy in magnetic tunnel junctions
Authors: Goto Minori , Kobayashi Reika , Okuno Ryota , Mizuno Tomohito , Yamane Takekazu , Degawa Naomichi , Suzuki Tsuyoshi , Shimura Atsushi , Aoki Susumu , Urabe Junichiro , Hara Shinji , Nomura Hikaru , Suzuki Yoshishige 
Published: December 2021

Abstract
We investigated the heat controlled magnetic anisotropy (HCMA) in magnetic tunnel junctions with various junction sizes. We evaluated the HCMA from perpendicular magnetic anisotropy under a direct current voltage measured by the spin-torque diode technique. The maximum HCMA magnitude of 5.4 μJ (Wm)−1 was observed, and the HCMA increased with increasing diameter. Our results can be explained by a simple heat dissipation model and suggest that the in-plane heat current affects HCMA.
Reproducible perovskite solar cells using a simple solvent-mediated sol−gel synthesized NiO
x
hole transport layer
Authors: Muslih Ersan Y. , Shahiduzzaman Md. , Akhtaruzzaman Md. , Hossain Mohammad Ismail , Wang LiangLe , Alkhammash Hend I. , Alharthi Sami S. , Nakano Masahiro , Karakawa Makoto , Aminuzzaman Mohammod , Tey Lai-Hock , Sopian Kamaruzzaman , Nunzi Jean-Michel , Taima Tetsuya 
Published: December 2021

Abstract
A nickel oxide (NiO
x
) hole transport layer was made from nickel oxide powder by a simple process and non-stabilizer or chelating agent. We used ethanol as the main solvent and less than 2% nitric acid as the co-solvent. The formation reaction mechanism of the NiO
x
thin film was also studied. Perovskite solar cells (PSCs) with an optimum thickness of 70 nm exhibited a power conversion efficiency as high as 12.99%, which is superior to those of PSCs with their counterparts. The moisture stability of NiO
x-based devices (non-encapsulated) remained above 70% of their initial output after 700 h storage at ambient conditions.
STRATEGI PEMASARAN YANG EFEKTIF SEBAGAI UPAYA PENINGKATAN DAYA SAING UMKM BAGI ANGGOTA KOPDIT KOSAYU MALANG
Authors: Jovita Vicka Bayu Wardhani  
Published: December 2021

Kontribusi koperasi kredit bagi anggota tidak hanya dalam hal peminjaman modal usaha saja, melainkan juga dapat membantu memberikan tambahan pengetahuan bisnis dan pendampingan usaha kepada para anggota agar usaha yang dijalankan memiliki daya saing. Masalah yang terjadi minimnya pengetahuan manajemen koperasi terkait pengetahuan bisnis dan pendampingan usaha, sehingga kerjasama dengan akademisi (pengabdi) menjadi solusi yang tepat untuk menjawab permasalahan tersebut.Sasaran dalam program pengabdian ini adalah anggota kopdit Kosayu Malang. Terdapat tiga kegiatan, antara lain (1) Penyuluhan/seminar dengan pembahasan mengenai value proposition dan marketing mix usaha; (2) Diskusi terkait masalah pemasaran produk dan pemberian solusi untuk meningkatkan penjualan produk; (3) Pendampingan usaha bagi anggota, terkait pemasaran produk baik pemasaran secara offline maupun secara online.Melalui kegiatan seminar dengan judul “Marketing Strategy for UMKM”, para peserta mendapat tambahan wawasan terkait hal-hal apa saja yang wajib dilakukan oleh seorang pemasar serta upaya-upaya dalam meningkatkan penjualan di masa pandemi. Diskusi untuk menemukan solusi dari permasalahan pemasaran produk juga dilakukan di akhir kegiatan seminar. Selain mengadakan seminar dan diskusi, pendampingan terhadap usaha kecil milik anggota. Pendampingan bertujuan agar wawasan yang telah didapat anggota melalui seminar benar-benar diaplikasikan ke dalam usaha, sehingga usaha/bisnis yang dijalankan mengalami peningkatan berupa peningkatan penjualan maupun peningkatan kepuasan para pelanggannya. Hasil kegiatan pendampingan tersebut, anggota dapat memasarkan produk baik secara offline maupun secara online dengan cara/strategi yang tepat.
Keyword : Strategi pemasaran, daya saing UMKM
Theory of Figures to the Seventh Order and the Interiors of Jupiter and Saturn
Authors: Nettelmann N. , Movshovitz N. , Ni D. , Fortney J. J. , Galanti E. , Kaspi Y. , Helled R. , Mankovich C. R. , Bolton S. 
Published: December 2021

Abstract
Interior modeling of Jupiter and Saturn has advanced to a state where thousands of models are generated that cover the uncertainty space of many parameters. This approach demands a fast method of computing their gravity field and shape. Moreover, the Cassini mission at Saturn and the ongoing Juno mission delivered gravitational harmonics up to J
12. Here we report the expansion of the theory of figures, which is a fast method for gravity field and shape computation, to the seventh order (ToF7), which allows for computation of up to J
14. We apply three different codes to compare the accuracy using polytropic models. We apply ToF7 to Jupiter and Saturn interior models in conjunction with CMS-19 H/He equation of state. For Jupiter, we find that J
6 is best matched by a transition from an He-depleted to He-enriched envelope at 2–2.5 Mbar. However, the atmospheric metallicity reaches 1 × solar only if the adiabat is perturbed toward lower densities, or if the surface temperature is enhanced by ∼14 K from the Galileo value. Our Saturn models imply a largely homogeneous-in-Z envelope at 1.5–4 × solar atop a small core. Perturbing the adiabat yields metallicity profiles with extended, heavy-element-enriched deep interior (diffuse core) out to 0.4 R
Sat, as for Jupiter. Classical models with compact, dilute, or no core are possible as long as the deep interior is enriched in heavy elements. Including a thermal wind fitted to the observed wind speeds, representative Jupiter and Saturn models are consistent with all observed J

n
values.