bluuebunny/crossref_metadata_2025_split huggingface dataset:
Delusional misidentification syndrome and criminal acting out: A case report of maternal filicide
Authors: Ben Ammar Hanen , Hamdi Ghada , Brahmi Lina , Naceur Yomn , Khelifa Emira , Felhi Rania , Mnif Leila 
Published: July 2021

AbstractDelusional misidentification syndromes are associated with danger and may lead to homicide. Early assessment of the danger is a key part of the psychiatric examination. Compliance to treatment in psychosis is important to avoid the devastating consequences, for the perpetrator, the victim, and the community.
Synergistic Engineering of Defects and Heterostructures Enhance Lithium/Sodium Storage Properties of F‐SnO2‐x‐SnS2‐x Nanocrystals Supported on N,S‐Graphene
Authors: Yuan Xing , Zhao Xiaojun , Qiu Shuting , Song Yizhuo 
Published: July 2021

AbstractPhase engineering of the electrode materials in terms of designing heterostructures, introducing heteroatom and defects, improves great prospects in accelerating the charge storage kinetics during the repeated Li+/Na+ insertion/deintercalation. Herein, a new design of Li/Na‐ion battery anodes through phase regulating is reported consisting of F‐doped SnO2‐SnS2 heterostructure nanocrystals with oxygen/sulfur vacancies (VO/VS) anchored on a 2D sulfur/nitrogen‐doped reduced graphene oxide matrix (F‐SnO2‐x‐SnS2‐x@N/S‐RGO). Consequently, the F‐SnO2‐x‐SnS2‐x@N/S‐RGO anode demonstrates superb high reversible capacity and long‐term cycling stability. Moreover, it exhibits excellent great rate capability with 589 mAh g−1 for Li+ and 296 mAh g−1 at 5 A g−1 for Na+. The enhanced Li/Na storage properties of the nanocomposites are not only attributed to the increase in conductivity caused by VO/VS and F doping (confirmed by DFT calculations) to accelerate their charge‐transfer kinetics but also the increased interaction between F‐SnO2‐x‐SnS2‐x and Li/Na through heterostructure. Meanwhile, the hierarchical F‐SnO2‐x‐SnS2‐x@N/S‐RGO network structure enables fast infiltration of electrolyte and improves electron/ion transportation in the electrode, and the corrosion resistance of F doping contributes to prolonged cycle stability.
Characterization of Functional Groups in Estuarine Dissolved Organic Matter by DNP‐enhanced 15N and 13C Solid‐State NMR
Authors: Venel Florian , Nagashima Hiroki , Rankin Andrew G. M. , Anquetil Christelle , Klimavicius Vytautas , Gutmann Torsten , Buntkowsky Gerd , Derenne Sylvie , Lafon Olivier , Huguet Arnaud , Pourpoint Frédérique 
Published: July 2021

AbstractEstuaries are key ecosystems with unique biodiversity and are of high economic importance. Along the estuaries, variations in environmental parameters, such as salinity and light penetration, can modify the characteristics of dissolved organic matter (DOM). Nevertheless, there is still limited information about the atomic‐level transformations of DOM in this ecosystem. Solid‐state NMR spectroscopy provides unique insights into the nature of functional groups in DOM. A major limitation of this technique is its lack of sensivity, which results in experimental time of tens of hours for the acquisition of 13C NMR spectra and generally precludes the observation of 15N nuclei for DOM. We show here how the sensitivity of solid‐state NMR experiments on DOM of Seine estuary can be enhanced using dynamic nuclear polarization (DNP) under magic‐angle spinning. This technique allows the acquisition of 13C NMR spectra of these samples in few minutes, instead of hours for conventional solid‐state NMR. Both conventional and DNP‐enhanced 13C NMR spectra indicate that the 13C local environments in DOM are not strongly modified along the Seine estuary. Furthermore, the sensitivity gain provided by the DNP allows the detection of 15N NMR signal of DOM, in spite of the low nitrogen content. These spectra reveal that the majority of nitrogen is in the amide form in these DOM samples and show an increased disorder around these amide groups near the mouth of the Seine.
On the optimum binding energy for the hydrogen evolution reaction: How do experiments contribute?
Authors: Exner Kai S. 
Published: July 2021

AbstractBinding energies of reaction intermediates are largely used to comprehend activity trends in a class of electrode materials. For a two‐electron process, such as the hydrogen evolution reaction (HER), it is a well‐established paradigm that the optimum electrocatalyst binds adsorbed hydrogen thermoneutrally at zero overpotential. While this picture was challenged recently by means of density functional theory (DFT) calculations and microkinetic considerations, reporting a shift of the optimum binding energy to strong or weak bonding with increasing overpotential, now experiments show further evidence for this theory. This perspective article juxtaposes the different views of the optimum binding energy for the HER by means of the Sabatier principle, microkinetic considerations, DFT calculations, and experiments, and provides an outlook of potential future investigations by the combination of experiments with DFT aiming at sustainable materials development for the hydrogen electrocatalysis.
A survey of problematic database code fragments in software systems
Authors: Alshemaimri Bader , Elmasri Ramez , Alsahfi Tariq , Almotairi Mousa 
Published: July 2021

AbstractDatabase code fragments exist in software systems by using Structured Query Language (SQL) as the standard language for relational databases. Traditionally, developers bind databases as backends to software systems for supporting user applications. However, these bindings are low‐level code and implemented to persist user data, so Object Relational Mapping (ORM) frameworks take place to abstract database access details. Both approaches are prone to problematic database code fragments that negatively impact the quality of software systems. We survey problematic database code fragments in the literature and examine antipatterns that occur in low‐level database access code using SQL and high‐level counterparts ORM frameworks. We also study problematic database code fragments in different and popular software architectures such as Service‐Oriented Architecture, Microservice Architecture, and Model View Controller. We create a novel categorization of both SQL schema and query antipatterns in terms of performance, maintainability, portability, and data integrity.
Dehydrogenation properties of hydride‐hydroxide systems containing potassium
Authors: Noto Nozomi , Isobe Shigehito , Hashimoto Naoyuki 
Published: July 2021

SummaryIn this research, dehydrogenation properties of several hydride‐hydroxide systems containing KH and KOH have been evaluated. Six types of hydride‐hydroxide systems (KH‐M[OH]n, MHm‐KOH, M: Li, Na, Mg) were prepared by ball milling method. We expected reaction formula of these six systems with assumption, that is, oxides would form after dehydrogenation. The hydrogen desorption properties of these systems were evaluated by TG‐DTA and MS. From the results of XRD before and after dehydrogenation, we obtained actual reaction formulas, which were different from expected formulas. Among six systems, it was confirmed that only KH‐LiOH system dehydrogenated in endothermic. This means that KH‐LiOH system can reversibly ab/desorb hydrogen in principle. However, it is calculated that extremely high pressure of GPa order is required for rehydrogenation of KH‐LiOH system.
Coarse sediment supply sets the slope of bedrock channels in rapidly uplifting terrain: Field and topographic evidence from eastern Taiwan
Authors: Lai Larry Syu‐Heng , Roering Joshua J. , Finnegan Noah J. , Dorsey Rebecca J. , Yen Jiun‐Yee 
Published: July 2021

AbstractThe incision rate and steepness of bedrock channels depend on water discharge, uplift rate, substrate lithology, sediment flux, and bedload size. However, the relative role of these factors and the sensitivity of channel steepness to rapid (>1 mm yr−1) uplift rates remain unclear. We conducted field and topographic analyses of fluvial bedrock channels with varying channel bed lithology and sediment source rock along the Coastal Range in eastern Taiwan, where uplift rates vary from 1.8 to 11.8 mm yr−1 and precipitation is relatively consistent (1.5–2.7 m yr−1), to evaluate the controls on bedrock channel steepness. We find that channel steepness is independent of rock uplift rate and annual precipitation but increases monotonically with sediment size and substrate strength. Furthermore, in reaches with uniform substrate lithology (mudstone and flysch), channel steepness systematically varies with sediment source rock but not with channel width. When applied to our data, a mechanistic incision model (saltation‐abrasion model) suggests that the steepness of Coastal Range channels is set primarily by coarse‐sediment supply. We also observe that larger particles are mainly composed of resistant lithologies derived from volcanic rocks and conglomerates. This result implies that hillslope bedrock properties in the source area exert a dominant control on the steepness of proximal channels through coarse‐sediment production in this setting. We propose that channel steepness may be insensitive to uplift rate and flow discharge in fast‐uplifting landscapes where incision processes are set by coarse sediment size and supply. Models assuming a proportionality between incision rate and basal shear stress (stream power) may not fully capture controls on fluvial channel profiles in landslide‐dominated landscapes. Processes other than channel steepening, such as enhanced bedload impacts and debris‐flow scour, may be required to balance rock uplift and incision in these transport‐limited systems.
At the Crossroads: Caribbean Women and (Black) Feminist Ethnography in the Time of HIV/AIDS
Authors: Jolly Jallicia 
Published: July 2021

AbstractThis article illustrates how feminist analyses and insights have offered anthropology expansive ethnographic possibilities as it charts possible futures for doing more ethically and politically invested work that emerges from the lives and experiences of Black women and women in the Global South. It takes on the problematics of situatedness, difference, reflexivity, and writing about women's lives in the (feminist) anthropology of HIV/AIDS to challenge the omission and misrepresentation of multiple‐voiced subjects and non‐European experiences as well as the elided racial and gendered experiences of HIV/AIDS. I situate myself within the decolonial turn and the scholarly and political genealogies of Black feminist anthropology to explore the challenges and opportunities of feminist ethnography in the era of “the end of AIDS.” Using ethnographic work on the experiences of HIV‐positive women in Kingston, Jamaica, conducted between 2015 and 2018, I foreground the life and death of Shanna, a mother of four to argue that the lives and afterlives of HIV‐positive Black Caribbean women expand the heterogeneous inheritances of feminist ethnography by offering insights on how to envision futures that are attentive to cross‐cultural experiences, embodied realities, social location, and structural condition. As I reconsider my own relationship to feminist ethnography and anthropology, I ask:How can (Black) feminist ethnography grapple with the ethics around HIV/AIDS and death while addressing the long‐standing problematic within feminist anthropology of relating to subjects in the field and writing about evolving subjectivities?
Developmental toxicity, antioxidant, and marker enzyme assessment of swertiamarin in zebrafish (Danio rerio)
Authors: Perumal Sasidharan , Gopal Samy Madhana V. , Subramanian Dharaneedharan 
Published: July 2021

AbstractA secoiridoid glycoside called swertiamarin has been widely used as a herbal medicine for many decades. In particular, swertiamarin from the Enicostema axillare herb has been used as a multipurpose drug to treat innumerable health problems. As this medicine is consumed orally, its toxicity level should be determined. To examine the safety of this compound, toxicology work was done in zebrafish, and this is the first report to describe swertiamarin toxicity in zebrafish. Zebrafish embryos were used in this swertiamarin toxicity study, and morphological changes were observed. Further, the compound was also studied in adult zebrafish to determine the impact of the compound on the fish liver. Enzyme profiling with superoxide dismutase, glutathione peroxidase, catalase, reduced glutathione levels, glutathione S‐transferase, lactate dehydrogenase, glutamic oxaloacetic transaminases, lipid peroxidation, Na+/K+‐ATPase, and glutamic pyruvic transaminases) was evaluated (p ≤ 0.05). Results suggest that swertiamarin is a safe drug only at a low concentration (40 µM). This study also shows that even herbal medicinal compounds may be toxic to humans at higher dosages. Hence, irrespective of whether a drug is synthetic or natural, it needs to be tested for its toxicity before use in humans.
Calculation of anharmonic effect on the reactions of small sulfur‐containing molecules with NO/NO2 in combustion
Authors: Hu Wenye , Chen Yuanpeng , Yang Kun , Yu Hongjing , Wang Shiye , Yao Li 
Published: July 2021

AbstractNitrogen oxides and sulfur oxides are the main pollutants that destroy the atmosphere, the emission and control of which have received wide attention. Notably, the interactions between nitrogen species and sulfur species occur extensively in combustion and the atmosphere. This article summarizes the 12 reactions of small sulfur‐containing molecules with NO/NO2 in combustion. The reaction rate constants of the 12 reactions at the temperature ranging from 300 to 4,000 K are calculated according to YL (Yao‐Lin) method and TS (transition state) theory. The results show that there is a large difference between the anharmonic and the harmonic rate constants for many reactions, especially at high temperature. In particular, the calculated values of the reactions S + NO2 → SO + NO, N + SO2 → SO + NO, and SH + NO2 → HSO + NO are in good agreement with other theoretical or experimental ones. Finally, the kinetic and thermodynamic parameters are calculated according to the anharmonic and harmonic rate constants as well as the least square methods. All these indicate that the anharmonic effect cannot be ignored and YL method is feasible.
Comparison of flap reconstruction for soft tissue sarcomas of the foot and ankle
Authors: Mallett Katherine E. , Houdek Matthew T. , Honig Rachel L. , Bakri Karim , Rose Peter S. , Moran Steven L. 
Published: July 2021

AbstractBackgroundFoot and ankle soft tissue sarcomas (STS) are challenging for reconstruction due to limited surrounding soft tissue and weight‐bearing requirements. Currently, there is a paucity of data examining the outcome of flap reconstruction following resection of a foot and ankle sarcoma.MethodsWe reviewed 44 (31 female, 13 male) patients with STS arising from the ankle or foot which required coverage in the form of a free (n = 21), pedicled (n = 13), or rotational perforator flap (n = 10). The mean tumor size was 6 ± 5 cm, with 39 (89%) patients receiving radiotherapy. The mean follow‐up was 10 ± 7 years.ResultsThere were no cases of amputation due to flap failure, with a 10‐year limb salvage rate of 84%. Complications occurred in 19 (43%) patients, most commonly wound infections. There was no difference in the incidence of complications between patients undergoing a free flap and pedicled or perforator flap (odds ratio = 0.97, p = 1.0); with no difference in the mean Musculoskeletal Tumor Society (MSTS) score between patients with a free flap versus a pedicled/perforator flap (84% vs. 76%, p = 0.11).ConclusionFlap reconstruction is an essential part of limb salvage for foot and ankle STS. At final follow‐up nearly all the patients are ambulatory with an acceptable MSTS score.
Dealing with trend uncertainty in empirical estimates of European rainfall climate for insurance risk management
Authors: Jewson Stephen , Dallafior Tanja , Comola Francesco 
Published: July 2021

AbstractThe insurance industry uses mathematical models to estimate the risks due to future natural catastrophes. For climate‐related risks, historical climate data are a key ingredient used in making the models. Historical data for temperature and sea level often show clear and readily quantified climate change driven trends, and these trends would typically be accounted for when building risk models by adjusting earlier values to render the earlier data relevant to the future climate. For other climate variables, such as rainfall in many parts of the world, the questions of whether there are climate change driven trends in the historical data, and how to quantify them if there are, are less simple to answer. We investigate these questions in the context of European rainfall with a specific focus on how to deal with the uncertainty around trend estimates. We compare 10 empirical methodologies that one might use to model and predict trends, including traditional statistical testing and alternatives to statistical testing based on standard methods from model selection and model averaging. We emphasize prediction and risk assessment, rather than detection of trends, as our goal. Viewed in terms of this goal, the methods we consider each have qualitative and quantitative advantages and disadvantages. Understanding these advantages and disadvantages can help risk modellers make a choice as to which method to use, and based on the results we present, we believe that in many common situations model averaging methods, as opposed to statistical testing or model selection, are the most appropriate.
The characteristics and risk factors of healthcare‐seeking men with lower urinary tract symptoms in China: Initial report from the POInT group
Authors: Song Qi‐Xiang , He Fan , Sun Xionglin , Liu Ke , Chen Zhong , Li Mingzhao , Lin Jianhai , Xu Zhihui , Li Yan , Zhang Yaoguang , Huang Hai , Zhang Yi , Ye Xiaofei , Peng Yonghan , Li Longkun , Yin Lei , Gao Xiaofeng , Song Bo , Sun Yinghao , Wang Jianye , Xue Wei , Abrams Paul ,   for the Prostatic Obstruction Investigation Team (POInT)
Published: July 2021

AbstractAimsTo investigate the clinical characteristics of health care‐seeking men presenting with lower urinary tract symptoms (LUTS) in China and to reveal risk factors for symptom severity.MethodsThis multicenter, hospital‐based, cross‐sectional study recruited 1477 eligible male subjects, who were at least 45 years, seeking health care at 9 participating hospitals across the mainland China. The general medical information and subjective symptoms were recorded, followed by the measurement of prostate volume, urodynamic indices, and laboratory tests for kidney function, plus glucose/lipid metabolism. Univariate and multivariate linear regression were employed for the detection of risk factors for symptom severity.ResultsThe proportion of mild, moderate, and severe LUTS was 14.6%, 32.6%, and 52.8%, respectively, with 62.2% reporting the triple combination of storage, voiding, and postmicturition symptoms. Median prostate volume was 44.6 ml, and 71.1% were experiencing comorbidities. Thirteen independent risk factors for LUTS severity were identified, namely, nocturnal voiding episodes and the presence of straining and weak steam; the triple combination of symptom subtypes; general and nocturia quality of life; Qmax and bladder outlet obstruction index; and numbers of comorbidities, hypertension, estimated glomerular filtration rate, and cholesterol and glycosylated hemoglobin.ConclusionsThe majority of health care‐seeking LUTS men present with moderate‐to‐severe and overlapping symptoms, with a high prevalence of both lower urinary tract dysfunction and systemic comorbidities. The evidence from both urological and nonurological independent risk factors demonstrate the multifactorial nature of LUTS, for which a multidisciplinary management is essential.
Neoadjuvant Treatment with Angiogenesis-Inhibitor Dovitinib Prior to Local Therapy in Hepatocellular Carcinoma: A Phase II Study
Authors: Woei-A-Jin F.J. Sherida H. , Weijl Nir I. , Burgmans Mark C. , Fariña Sarasqueta Arantza , Tom van Wezel J. , Wasser Martin N.J.M. , Coenraad Minneke J. , Burggraaf Jacobus , Osanto Susanne 
Published: July 2021

Abstract

Background
Hepatocellular carcinoma (HCC) recurrence rates following locoregional treatment are high. As multireceptor tyrosine kinase inhibitors targeting vascular endothelial growth factor receptors (VEGFRs) are effective in advanced HCC, we assessed the efficacy and safety of neoadjuvant systemic treatment with dovitinib in early- and intermediate-stage HCC.

Materials and Methods
Twenty-four patients with modified Child-Pugh class A early- and intermediate-stage HCC received neoadjuvant oral dovitinib 500 mg daily (5 days on/2 days off) for 4 weeks, followed by locoregional therapy. Primary endpoints were objective response rates and intratumoral blood flow changes. Secondary endpoints were safety, pharmacodynamical plasma markers of VEGFR-blockade, time to progression (TTP), and overall survival (OS).

Results
Modified RECIST overall response rate was 48%, including 13% complete remission, and despite dose reduction/interruption in 83% of patients, intratumoral perfusion index decreased significantly. Grade 3–4 adverse events, most frequently (on-target) hypertension (54%), fatigue (25%), and thrombocytopenia (21%), occurred in 88% of patients. Plasma VEGF-A, VEGF-D, and placental growth factor increased significantly, whereas sTie-2 decreased, consistent with VEGFR-blockade. Following neoadjuvant dovitinib, all patients could proceed to their original planned locoregional treatment. No delayed toxicity occurred. Seven patients (three early, four intermediate stage) underwent orthotopic liver transplant after median 11.4 months. Censoring at transplantation, median TTP and OS were 16.8 and 34.8 months respectively; median cancer-specific survival was not reached.

Conclusion
Already after a short 4-week dovitinib treatment period, intratumoral blood flow reduction and modest antitumor responses were observed. Although these results support use of systemic neoadjuvant strategies, the poor tolerability indicates that dovitinib dose adaptations are required in HCC.

Implications for Practice
Orthotopic liver transplantation may cure early and intermediate-stage hepatocellular carcinoma. Considering the expected waiting time &gt;6 months because of donor liver scarcity, there is an unmet need for effective neoadjuvant downsizing strategies. Angiogenesis inhibition by dovitinib does not negatively affect subsequent invasive procedures, is safe to administer immediately before locoregional therapy, and may provide a novel treatment approach to improve patient outcomes if tolerability in patients with hepatocellular carcinoma can be improved by therapeutic drug monitoring and personalized dosing.
Statistical analysis of 12 years of standardized accelerated aging in photovoltaic‐module certification tests
Authors: Gebhardt Paul , Mülhöfer Georg , Roth Arnd , Philipp Daniel 
Published: July 2021

AbstractAccelerated aging tests according to international standards (IEC 61215 and IEC 61730) have been used for many years to investigate photovoltaic (PV) module reliability. In this publication, we share a thorough analysis of the tests that were acquired over a time span of 12 years across a wide range of technologies and module generations. The results can serve as a valuable reference to evaluate the reliability of module types and prototypes beyond the use of standardized pass/fail criteria. Furthermore, this work can contribute to ongoing revisions of these standards. In more technical depth, we share the failure rates of different accelerated aging tests. We further discuss trends that are apparent over the investigated decade and reveal which test sequences have become the most relevant to differentiate different PV module types in terms of reliability.