bluuebunny/crossref_metadata_2025_split huggingface dataset:
A replication study on implicit feedback recommender systems with application to the data visualization recommendation
Authors: Lak Parisa , Bozanta Aysun , Kavaklioglu Can , Cevik Mucahit , Basar Ayse , Petitclerc Martin , Wills Graham 
Published: November 2021

AbstractIn this study, we compare the Bayesian personalized ranking (BPR) algorithms with two recent state‐of‐the‐art algorithms, namely, noisy‐label robust Bayesian point‐wise optimization (NBPO) and Light Graph Convolution Network (LightGCN) algorithms, to validate and generalize their performance by using six publicly available datasets and one proprietary dataset containing web‐based data visualization usage records. We follow the guidelines explained in the original studies to pre‐process the input data and evaluate these algorithms using various evaluation metrics. We also perform hyperparameter tuning for the recommendation algorithms to determine the optimal configuration resulting in the best recommendation quality. We observe that the best hyperparameter configuration varies based on the algorithms and the datasets. The results of our analysis show some similarities with the results of the original studies while differing in certain respects. We observe that adaptive oversampling BPR (AOBPR) and LightGCN algorithms generate higher quality recommendations than the other algorithms. However, algorithm convergence rates vary significantly for each dataset. We note that the AOBPR approach is particularly useful for data visualization recommendation task, and can contribute to the improved recommendations in practice.
Two‐period information‐sharing and quality decision in a supply chain under static and dynamic wholesale pricing strategies
Authors: Zhao You , Hou Rui , Lin Xiaogang , Lin Qiang 
Published: November 2021

AbstractWe consider a one‐to‐one supply chain consisting of a manufacturer and a retailer and study the retailer's two‐period information‐sharing decision problem. We develop a game‐theoretic model wherein the manufacturer produces a product at a certain level of quality to the retailer at a static wholesale price or at dynamic wholesale prices over two periods. The retailer determines whether to share the market demand information with the manufacturer. Conventional wisdom suggests that the retailer prefers not to share the information because of the double marginalization effect. Under the two‐period setting, we show that the retailer may disclose information to the manufacturer voluntarily. Specifically, if the manufacturer adopts the static wholesale pricing strategy, sharing (no) information over two periods is beneficial for the retailer when the quality cost coefficient is low (high). If the manufacturer implements the dynamic wholesale pricing strategy, it is beneficial for the retailer to share information only in the first period when the quality cost coefficient is moderate. When the quality cost coefficient is sufficiently low (high), the retailer prefers to share (no) information for both periods. Our result suggests that the manufacturer always benefits from the information‐sharing, that is, a “win‐win” outcome for the retailer and manufacturer may be achieved under certain conditions, which stands in sharp contrast to the literature on information‐sharing.
Andradite titanium: Preparation, characterization and metallurgical performance
Authors: Li Gang , Chen Dan , You Yang , Ding Chengyi , Pei Guishang , Chen Yun , Qiu Guibao , Lv Xuewei 
Published: November 2021

AbstractAndradite titanium (Ca3Fe2Si1.58Ti1.42O12, abbreviated as AT), which is a significant mineral phase in the sinter of titanium‐containing iron ore, was prepared via a solid‐state reaction with analytical reagents. The crystal structure, cold strength, and high‐temperature heat capacity were individually characterized, and the metallurgical performance, such as melting and reduction behavior, were measured. AT is a variant of andradite (Ca3Fe2Si3O12) formed by the Ti4+ substitution for Fe3+ in the octahedral sites and Fe3+ substitution for Si4+ in the tetrahedral sites. The compressive strength of AT was approximately 14.21 MPa, and its softening, melting, and flowing temperatures were 1453, 1483, and 1509 K, respectively. According to the differential scanning calorimetry measurements, the melting point was approximately 1502 K. The non‐isothermal reduction results revealed that AT was reduced to Fe, perovskite, and wollastonite in a single step, and the isothermal reduction test indicated that the reduction degree of AT was only 0.67 when reduced at 900°C for 150 min, and the order of reduction performance was Fe2O3 > Fe3O4 > CaO·2Fe2O3 > CaO·Fe2O3 > 2CaO·Fe2O3 > AT. The high‐temperature heat capacity of AT as a function of temperature was also measured and modeled.
The established and the challenger: A direct comparison of current cryoballoon technologies for pulmonary vein isolation
Authors: Moser Fabian , Rottner Laura , Moser Julia , Schleberger Ruben , Lemoine Marc , Münkler Paula , Dinshaw Leon , Kirchhof Paulus , Reissmann Bruno , Ouyang Feifan , Rillig Andreas , Metzner Andreas 
Published: November 2021

AbstractIntroductionCryoballoon (CB) ablation for pulmonary vein isolation (PVI) is an effective treatment of atrial fibrillation (AF). Recently, a novel cryoablation system was introduced. The aim of the study was to compare the safety, efficacy and biophysical characteristics of a novel cryoablation system (POLARx™; Boston Scientific) to a commonly used and clinically well characterized system (Arctic Front Advance Pro™, AFA; Medtronic).Methods and ResultsFifty consecutive patients with symptomatic AF, who underwent CB‐based ablation with the POLARx were compared to 50 consecutive patients treated with the AFA. Acute PVI was achieved in 99.8% (POLARx 99.5%, AFA 100%, p = 1.00). Time to isolation (TTI) was comparable in both groups (POLARx 35 [27, 48] s, AFA 30 [21, 43] s, p = 0.165). The POLARx showed a lower balloon temperature at TTI (POLARx −44 [−50, −36] °C, AFA −31 [−38, −21] °C, p < 0.001) and lower nadir temperature (POLARx −60 [−65, −55] °C, AFA −48 [−54, −45] °C, p < 0.001). Procedure time (POLARx 80 [60, 105] min, AFA 62 [42, 80] min, p < 0.001), fluoroscopy time (POLARx 17 [13, 22] min, AFA 11 [7, 16] min, p < 0.001) and freeze cycles per patient (POLARx 5 [4, 6], AFA 4.5 [4, 5], p = 0.002) were higher in the POLARx group. Two cerebral ischemic events occurred in the POLARx group, two patients in each group had phrenic nerve injury.ConclusionBoth systems enable effective isolation of pulmonary veins. The POLARx required longer procedure and fluoroscopy times. Larger, prospective and randomized studies are needed to assess long‐term efficacy and safety of this technology.
A novel model of a biomechanically induced osteoarthritis‐like cartilage for pharmacological in vitro studies
Authors: Sauerland Katrin , Wolf Amela , Schudok Manfred , Steinmeyer Juergen 
Published: November 2021

AbstractExcessive pressure or overload induces and aggravates osteoarthritic changes in articular cartilage, but the underlying biomechanical forces are largely ignored in existing pharmacological in vitro models that are used to investigate drugs against osteoarthritis (OA). Here, we introduce a novel in vitro model to perform pathophysiological and pharmacological investigations, in which cartilage explants are subjected to intermittent cyclic pressure, and characterize its ability to mimic OA‐like tissue reactivity. Mechanical loading time‐dependently increased the biosynthesis, content and retention of fibronectin (Fn), whereas collagen metabolism remained unchanged. This protocol upregulated the production and release of proteoglycans (PGs). The release of PGs from explants was significantly inhibited by a matrix metalloproteinase (MMP) inhibitor, suggesting the involvement of such proteinases in the destruction of the model tissue, similar to what is observed in human OA cartilage. In conclusion, the metabolic alterations in our new biomechanical in vitro model are similar to those of early human OA cartilage, and our pharmacological prevalidation with an MMP‐inhibitor supports its value for further in vitro drug studies.
Fracture strength of teeth with coronal destruction after core build‐up restoration with bulk fill materials
Authors: Oliveira Carlos Rangel de Moura , Reis Érica Gouveia Jorge , Tanomaru‐Filho Mário , Reis José Maurício dos Santos Nunes 
Published: November 2021

AbstractObjectiveThis study aimed to evaluate the fracture strength and failure modes of different core techniques in teeth with simulated coronal destruction.Materials and methodsForty teeth were endodontically prepared and the specimens were divided into four experimental groups (n = 10) according to the core composition: Filtek One Bulk Fill‐FOBF, Filtek Z350 XT‐FZ350 (standard group), Filtek Bulk Fill Flow‐FBFF, and LuxaCore Z‐LCZ. CAD/CAM Monolithic zirconia crowns were obtained and cemented with RelyX U200. After storage in distilled water at 37°C for 48 h, the specimens were subjected to thermal cycling and to compressive strength mechanical tests. Statistical analyses (α = 0.05) were performed by non‐parametric Kruskal–Wallis, Dunn post hoc, and Fisher's exact tests.ResultsNo significant differences (p > 0.05) were observed among FOBF, FZ350, and FBFF (mean ranks = 20.30, 12.20, and 23.20, respectively). LCZ (mean rank = 26.30) produced results similar to those of FOBF and FBFF (p > 0.05) and higher than those of FZ350 (p = 0.042). The most frequent type of failure was irreparable, regardless of the experimental condition. The lowest percentages of reparable fractures were produced by FOBF group (10%).ConclusionsThe use of bulk fill materials, including the “core‐and‐post” LCZ dual‐cure resin composite, did not impair the fracture strength of endodontically treated teeth with coronal destruction.Clinical significanceResin composite bulk fill materials that can be used as a core‐and‐post cementation in an only stage are interesting, since they enable clinicians to work with one only material, and avoid several materials interfaces, technical sensitivity, and longer chair‐time due to multistep procedures.
Stress distribution of a novel bundle fiber post with curved roots and oval canals
Authors: Yanık Deniz , Turker Nurullah 
Published: November 2021

AbstractObjectiveThe aim of this study was to compare the stress distribution of teeth with curved and straight roots with oval and round canals restored with the bundle and conventional post systems.Material and methodsSix three‐dimensional premolars were modeled with round and oval canals, and curved roots using the software. The bundle post and the round posts were modeled. All post models were placed on the canals. The models were subjected to 200 N oblique loading. The results were evaluated by von Mises stresses.ResultsThis study demonstrated that the bundle post showed higher stress values compared to the conventional post. The stresses in the oval canal were higher than those in the round canal. The highest stress values were found in the curved roots. The stress distribution on the curved roots was observed in the middle and apical third of the canal.ConclusionThe bundle post presented higher stress compared to conventional posts. Besides, a more uniform stress distribution was observed in the bundle groups.Clinical significanceWhen a post was required in extremely irregular, wide canals and curved roots, the bundle post was the material of choice. Canal and root morphology influenced stress distribution.
Effectiveness of an adaptive flood management strategy using riparian risk assessment and a tolerability criterion
Authors: Shin Eun Taek , Lee Sangeun , Lee Jongso , Song Chang Geun 
Published: November 2021

AbstractOwing to climate change, torrential rains and typhoons have become more frequent. However, to cope with this threat, conventional flood management suffers from limitations and difficulties because of the practice of uniform flood prevention measures being applied to all stream sections according to river grade classification. A wide array of measures should be considered to differentiate flood protection targets: adaptive flood management strategy is one such effort. One obstacle, however, to introducing such a measure is lack of clarity over how to divide quantitatively the degree of risk from flooding. In this study, we undertook quantitative risk assessment to determine the risk level in a riparian zone. We compared our results with statistically derived societal risk limits to determine whether the risk level was acceptable within the framework of the tolerance risk limit. We found that the flood risk could be reduced through adaptive flood management.
The Intrauterine Device Experience Among Transgender and Gender‐Diverse Individuals Assigned Female at Birth
Authors: Abern Lauren , Krempasky Chance , Diego Daniela , De Guzman Glendell , Kiely Kristen , Cook Jake , Maguire Karla 
Published: November 2021

IntroductionThe intrauterine device (IUD) is a long‐acting and highly efficacious form of contraception that can also be used for menstrual suppression. Although IUD use is increasing, the type chosen, appeal, and satisfaction among individuals who are transgender and gender diverse and assigned female at birth (TGD‐AFAB) is unknown. The purpose of this study is to evaluate IUD usage among TGD‐AFAB individuals.MethodsTGD‐AFAB individuals who had an IUD for a minimum of 6 months at the time of completing the survey or had one in the past completed an anonymous online survey. Descriptive statistics were used to analyze the data.ResultsOne hundred and five TGD‐AFAB individuals completed the survey. Among participants who were sexually active, 88% reported they were in a relationship in which it was possible to get pregnant. There were 85 individuals who currently had an IUD: 62 (73%) chose a 52‐mg levonorgestrel (LNG) IUD, 5 (6%) chose a lower‐dose LNG IUD, 17 (20%) chose the copper IUD, and one chose an IUD unavailable in the United States. Menstrual suppression was the primary reason for choosing a 52‐mg LNG IUD (58%). Most individuals who opted for a copper IUD did so to avoid hormonal contraception (71%). Participants reported experiencing IUD side effects; however, few desired removal. Among the 36 respondents who had an IUD in the past, the most frequent reasons for removal were expiration of the device (LNG IUDs) and undesired side effects (copper IUD). Approximately half of participants who had an IUD removed had it replaced with another IUD.DiscussionPregnancy can occur among TGD‐AFAB individuals even if they are on testosterone and amenorrheic. IUDs are well tolerated in this population, with few current users desiring removal for unwanted side effects. Clinicians should counsel TGD‐AFAB individuals about the contraceptive and noncontraceptive benefits of IUDs and expected side effects.
Investigating predictors of self‐care behavior among homebound older adults: The role of self‐efficacy, eHealth literacy, and perceived social support
Authors: Wong Arkers Kwan Ching , Bayuo Jonathan , Wong Frances Kam Yuet 
Published: November 2021

AbstractPurposeThis study aimed to investigate the predictors of self‐care behavior among homebound older adults using the Health Empowerment theory as a framework.DesignThis was a cross‐sectional, predictive correlational study.MethodsSixty‐eight participants were randomly selected from five Hong Kong community centers from May 21, 2020 through July 20, 2020. Self‐care behaviors were assessed using the Chinese version of Partners in Health. Self‐efficacy, eHealth literacy, and perceived social support were assessed as potential predictors of self‐care behaviors. A multiple linear regression analysis was adopted to examine the predictive effects.ResultsThe age of the sample ranged from 61 to 85 years (mean = 71.7, SD = 6.0). Participants who reported having sufficient or more than sufficient financial resources had better self‐care behaviors than those who claimed to have insufficient financial resources (F = 5.08, p = 0.009). Statistically significant correlations were found between the participants’ eHealth literacy (r = 0.54, p < 0.001), perceived social support (r = 0.60, p < 0.001), and self‐care behaviors. eHealth literacy (β = 0.13, p = 0.007) and perceived social support (β = 0.13, p < 0.001) were significant predictors of self‐care behaviors. Collectively, the three variables accounted for 41% of the variances in self‐care behaviors.ConclusionsThe findings in this study suggest that eHealth literacy and perceived social support are two key factors that predicted the self‐care behaviors of this vulnerable population.Clinical relevanceIn this technological era, the use of eHealth, together with enhanced social support, can lead to better self‐care among older adults, particularly those who are homebound.
Treatment protocols and efficacy of combined laser with medical treatment modalities in vitiligo
Authors: Mohammadi Saman , Amiri Rezvan , Khalili Maryam , Iranmanesh Behzad , Aflatoonian Mahin 
Published: November 2021

AbstractBackgroundsNowadays, lasers are used for treatment of vitiligo in difficult‐to‐treat areas and refractory lesions. Combination of lasers with other medical modalities can provide higher efficacy, faster response rate, and higher compliance of patients to treatment.AimIn this article, we reviewed articles regarding safety, efficacy, and treatment protocols of combined laser with other medical modalities.MethodsWe searched articles with relevant key words in Google scholar and PubMed. Inclusion criteria were articles in English language since January 2000 until March 2021that evaluate combination of laser with other topical or systemic medical treatments.ResultsA total of 42 articles evaluated efficacy of lasers [excimer, carbon dioxide (CO2), erbium‐doped yttrium‐aluminum‐garnet (Er:YAG), and non‐ablative resurfacing laser] combined with topical or systemic medical treatment modalities. Effective response rate (more than 50% improvement) varied between 7.7% and 92%. Initial repigmentation observed between 4 and 13 weeks after beginning of treatment.ConclusionCombination of laser with medical modalities leads to more rapid repigmentation, superior efficacy, and better compliance of patients with localized non‐segmental type of vitiligo compared to monotherapy. Combination of excimer laser with topical therapy might be suggested for recalcitrant vitiligo lesions in face and neck. Combination of fractional ablative resurfacing lasers with topical therapy, especially 5‐flurouracil, can be recommended particularly in recalcitrant acral and bony prominent areas. Further studies are required to achieve conclusive evidence in order to define the best stage of vitiligo for laser therapy and most effective combined treatment regimen.
Treating hypothyroidism is not always easy: When to treat subclinical hypothyroidism, TSH goals in the elderly, and alternatives to levothyroxine monotherapy
Authors: Ross Douglas S. 
Published: November 2021

AbstractThe majority of patients with hypothyroidism feel better when levothyroxine treatment restores thyroid‐stimulating hormone (TSH) concentrations to normal. Increasingly, a significant minority of patients remain symptomatic and are dissatisfied with their treatment. Overzealous treatment of symptomatic patients with subclinical hypothyroidism may contribute to dissatisfaction among hypothyroidism patients, as potential hypothyroid symptoms in patients with minimal hypothyroidism rarely respond to treatment. Thyroid hormone prescriptions have increased by 30% in the United States in the last decade. The diagnosis of subclinical hypothyroidism should be confirmed by repeat thyroid function tests ideally obtained at least 2 months later, as 62% of elevated TSH levels may revert to normal spontaneously. Generally, treatment is not necessary unless the TSH exceeds 7.0–10 mIU/L. In double‐blinded randomized controlled trials, treatment does not improve symptoms or cognitive function if the TSH is less than 10 mIU/L. While cardiovascular events may be reduced in patients under age 65 with subclinical hypothyroidism who are treated with levothyroxine, treatment may be harmful in elderly patients with subclinical hypothyroidism. TSH goals are age dependent, with a 97.5 percentile (upper limit of normal) of 3.6 mIU/L for patients under age 40, and 7.5 mIU/L for patients over age 80. In some hypothyroid patients who are dissatisfied with treatment, especially those with a polymorphism in type 2 deiodinase, combined treatment with levothyroxine and liothyronine may be preferred.
Factors determining bryophyte species richness and community composition on insular siliceous erratic boulders in calcareous landscapes
Authors: Hepenstrick Daniel , Bergamini Ariel , Webster Clare , Ginzler Christian , Holderegger Rolf 
Published: November 2021

AbstractAimPleistocene erratic boulders are rocks that were relocated by glaciers during the Ice Ages. When their geology differs from the geology of the landscape that surrounds them, erratic boulders form habitat islands for regionally rare, edaphically specialised, rock‐dwelling cryptogams (bryophytes, ferns and lichens). Such boulders constitute terrestrial model systems for exploring island biogeographic predictions and the effect of environmental variables on species diversity and community composition, which we studied in order to provide basic knowledge of the ecology, with relevance for the conservation, of these unusual island systems.LocationSiliceous erratic boulders in the calcareous Swiss Plateau and Jura Mountains.MethodsFor 160 erratic boulders we recorded all bryophyte species and a diverse set of environmental variables. For all species and for specialist species (acidophile rock‐dwellers) separately, we analysed species–area relationships and nestedness, and explored relationships between environmental variables, species diversity and community composition.ResultsWe found 138 bryophyte species, 19 of which were specialists of erratic boulders. A steeper species–area curve for boulder specialists than for total species richness underlined the island properties of boulders for specialist species. Large boulders were more likely to harbour numerous boulder specialists and communities on small boulders were nested within the communities present on large boulders. However, at the landscape level small boulders contributed more specialist species than a few large boulders of the same surface area. Erratic boulders near settlements were less likely to harbour boulder specialists. Boulders in open land harboured different and more specialist species than boulders in forests.ConclusionsLarge undisturbed erratic boulders in open land harbour rare bryophyte communities with a large number of specialist species. Conservation should thus prioritise this type of boulders. Furthermore, conserving large boulders is logistically easier, and they may function as flagships for small boulders that also contribute to the biodiversity within landscapes.