bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beneficial impact of Nesfatin-1 on reproductive dysfunction induced by nicotine in male rats: Possible modulation of autophagy and pyroptosis signaling pathways
Authors: Madi N. M , Abo El Gheit R. E. , Barhoma R. A. , El Saadany A. , Alghazaly G. M. , Marea K. , El-Saka M. H. 
Published: June 2021

AbstractThis study was conducted to explore the beneficial impact of nesfatin-1 on reproductive dysfunction induced by nicotine (NT) in male rats with possible modulation of autophagy and pyroptosis signaling pathways. This research was performed on 40 Wistar male rats. They were distributed into four groups: control, normal+nesfatin-1, NT, and NT+nesfatin-1. At the end of the experimental period, the serum was separated for assay of testosterone, FSH and LH. Also, sperm parameters were determined. Histopathological examination of testicular tissue and immunohistochemical analysis was done for mammalian target of rapamycin, AMP-activated protein kinase, and mitogen-activated protein kinases including phosphorylated extracellular signal regulated kinase and phosphorylated cJun N-terminal kinase. Relative gene expression was determined for testicular nucleotide oligomerization domain (NOD)-like receptors proteins andCaspase-1, and autophagy markers including microtubule-associated protein 1 light chain 3 alpha andBeclin-1. Also, the following testicular parameters were assayed: 3β-hydroxysteroid dehydrogenase, 17β-hydroxysteroid dehydrogenase, malondialdehyde, superoxide dismutase activity, catalase, glucose-6 phosphate dehydrogenase, reactive oxygen species, caspase-3 activity, IL-1β, IL-18, mitochondrial transmembrane potential and Complex-I activity. The results revealed that the normal+nesfatin-1 group showed insignificant changes as compared to the control group. Meanwhile, the NT group exhibited prominent reproductive dysfunction in male rats. On the other hand, in the NT+nesfatin-1 group nesfatin-1 notably attenuated this reproductive dysfunction as evidenced by improvement of hormonal assay, sperm parameters, histopathological picture, immunohistochemical evaluation and real time relative gene expressions. In conclusion: Nesfatin-1 alleviated the impairment of male reproductive functions induced by NT via enhancement of autophagy pathways, suppression of pyroptosis, apoptosis, mitochondrial dysfunction and ROS production. Thus nesfatin-1 may offer a novel protective or therapeutic access for treating male infertility.
EFFECT OF VERMICOMPOST DOSES ON CANABIS SATIVA PHOTOSYNTHESIS-RELATED PARAMETERS, GROWTH AND YIELD
Authors: Stramkale Veneranda , Ievinsh Gederts , Vikmane Māra , Kirse Agnese , Kroica Ieva 
Published: June 2021

Hemp, Cannabis sativa is certainly a mul­tifunctional as well as a niche crop, due to great po­ten­tial for innovative use of its different products. Aspects of hemp mineral nutrition are very important in the cultivation of these plants, in particular to make cul­ti­vation environmentally friendly by replacing synthetic fertilizers with organic ones. Among organic fertilizers, vermicompost has gained particular attention within the last decades. Explaining the role of vermicompost, this study evaluated the effects of different doses of this fer­ti­lizer on hemps in two separate field studies. In a small-scale field experiment, the effect of two doses of ver­micompost and adequate concentrations of mineral elements fertilizers the growth, physiological condition, as well as yield of hemp was compared. The effect of increasing doses of vermicompost on the physiological condition and yield of hemp was analysed in a broader field experiment. The experiments were performed at the Viļāni Scientific Centre of the Agricultural Resour­ces and Economics, in 2017 and 2018, using the Latvian hemp cultivar ‘Pūriņi’. For the experiments, certified vermicompost produced by ‘Eko Zeme’ (Latvia) was used, which was produced from composted cow manure by adding grass biomass. In field experiment, the posi­tive effect of vermicompost on hemp growth was greater than the effect of equivalent mineral fertilizer con­centra­tions. When using vermicompost in increasing doses, better hemp growth (40–60 %) was observed at 5 and 10 t ha-1, stem yield increased on average by 40 % due vermicompost, seed yield ranging from 1.00 t ha-1 in control plants, to 1.56 t ha-1 in 20 t ha-1 in plants treated with 20 t ha–1 vermicompost plants. The weight of 1000 seeds per plant in all variants (from 13.54 to 13.85 g) was relatively close to the indicated maximum level (14.59 g). A statistically significant increase in chlo­ro­phyll concentration in plant leaves was observed under the influence of vermicompost. The increase in the Per­for­mance Index of the chlorophyll a fluorescence measu­rement was only for plants in individual experimental variants; regardless of how significant the increase in stem and seed yield was due to the respective doses of vermicompost. In general, the results characterize the growth of hemp in local agroclimatic conditions and allow to expect a stable increase in yield under the in­fluence of vermicompost.
PRODUCTIVITY OF DIFFERENT SOYBEAN CULTIVARS DEPENDING ON METEOROLOGICAL CONDITIONS AND GROWING MANNER IN LATGALE 2018–2020
Authors: Pekša Kintija , Justs Arnis , Stramkale Veneranda , Stramkalis Aldis , Zute Sanita 
Published: June 2021

In recent decades in Latvia and other European countries increased interest about growing protein-rich crops and especially soybeans (Glycine max). Although soybean cultivation experiments in Latvia have been carried out for some time, there is still insufficient knowledge about cultivating these plants in the country's climatic conditions. A field trials was carried out in 2018, 2019 and 2020 in the Latgale Agricultural Science Centre. The effect of three factors (A: soybean cultivar (A1 — ‘Lajma’, A2 — ‘Laulema’, A3 — ‘Merlin’, A4 — ‘Tiguan’, A5 — ‘Paradis’, A6 — ‘Touttis’); B: sowing rate (B1 — 40, B2 — 50, B3 — 60 germinable seeds per 1 m2); C: row spacing (C1 — 12.5 cm, C2 — 25 cm) on the development and yield formation of soybean was examined. The experiment was carried out in the framework of the project ‘New technologies and important to look for earlier cultivars to avoid farming risks.
EVALUATION OF CALCIUM CARBONATE CONTENT IN EGGSHELLS OF AVIAN, TURTLE, SNAIL, AND OSTRICH USING CHEMICAL ANALYSIS AND SCANNING ELECTRON MICROSCOPY
Authors: Umbraško Inta , Petjukevičs Aleksandrs , Batjuka Anna , Harlamova Nadežda 
Published: June 2021

In the present study, different eggs were collected and analyzed from five various animal species: European pond turtle (Emys orbicularis (Linnaeus, 1758)), giant African land snail (Achatina fulica (Bowdich, 1822)), common ostrich (Struthio camelus (Linnaeus, 1758)), white, light-brown, and dark-brown laying hen (Gallus gallus domesticus (Linnaeus, 1758) and European quail (Coturnix coturnix (Linnaeus, 1758). The typical mineral shell mainly composed of the calcite polymorph of CaCO3 but the eggshell consists of membranes, that composed mainly of proteins. The shell quality also could be assigned by several external and internal factors such as oviposition time, animal genotype and age, housing system (for poultry), and mineral nutrition complex. The CaCO3 content was determined by the standard titration method, coz the titration could provide a reliable method for evaluation of CaCO3 content in different types of eggshells. The structural surface characterization of eggshells was performed by scanning electron microscopy (SEM) with a field emission gun. In terms of chemical composition, ostrich eggshells generally did not differ much from those of laying hen, turtles, giant snails, or quail eggs, but the concentration of calcium carbonate was the highest. The average calcium carbonate content of various eggshells is between 84 and 98%. The thickness of the eggshell ranges from 0.08 to 1.89 mm, and it is not the same over the entire surface of the egg. At the sharp end of the egg, the shell is slightly thicker than at the blunt end. The purpose of this study was to study the quantitative content of calcium carbonate in various eggshells of different animals to draw further conclusions in which animals the eggshell contains the maximum amount of biological calcium carbonate.
TRANSVERSAL COMPETENCIES FOR DIGITAL READINESS AND DEVELOPMENT OF HUMAN CAPITAL IN ENGINEERING EDUCATION
Authors: Abuže Anda , Ļubkina Velta 
Published: June 2021

The research is carried out within the framework of Rezekne Academy of Technology, Latvia in cooperation with West Ukrainian National University, Ukraine LV – UA project “Gender aspects of digital readiness and development of human capital in regions” Nr.LV-UA/ 2018/3.Nowadays, educational institutions have to adapt to the new situation, make changes that would promote the transformation of the study process, promote the development of digital readiness and human capital.The aim of the research is to study the need for transversal competencies, innovation, entrepreneurship and development of digital readiness and human capital in engineering studies. The monographic and descriptive method has been applied for studying scientific literature and modeling method for a professional development plan.
Clinical and microbiological profile of diabetic foot ulcers in a tertiary care setup: a cross sectional analysis
Authors: Rai Siddharth , Uppal Harleen , Sharma Arvind Kumar , Gupta Anil Kumar 
Published: June 2021

Background: Diabetes associated neuropathy and vasculopathy leads to development of diabetic foot ulcers (DFU). They are responsible for considerable morbidity and a significant cost of health‐care worldwide. The magnitude of the problem becomes worse in regions where foot care is inadequate like in our country. The aim of the study to determine the microbiological profile and antimicrobial susceptibility pattern of organisms isolated from patients with diabetic foot ulcers. Methods: The study was a cross sectional study done at King George’s Medical College, Lucknow from 2012-2014 in Lucknow, Uttar Pradesh. Based on the inclusion criteria sample were collected from 112 patients. The standard protocol for the identification of microorganisms was followed. A descriptive analysis of the data was done.Results: Out of the 112 ulcers total 180 isolates were found. Of the 112 cases, 78 were monomicrobial, 32 were polymicrobial, and 2 cases were sterile on culture. The most common bacteria found was Staphylococcus aureus. Most of the staphylococcus isolated were sensitive to vancomycin, teicoplanin, cephalosporins, linezolid levofloxacin and pipercillin-tazobactum. Nearly 65% of S. aureus were methicillin‐resistant S. aureus.Conclusions: This study compiled clinical and microbiological profile of diabetic foot ulcers along with their antibiotic susceptibility patterns. Our study illuminates light on a high figure of neglected and poorly treated NHUs which could have been managed well and early treatment will prevent devastating consequences such as sepsis and amputation.
Artificial intelligence in healthcare
Authors: Shah Yamini D , Soni Shailvi M , Patel Manish P 
Published: June 2021

Artificial Intelligence (AI) is described as a field of science and engineering that is concerned with the artificial appreciation of what is generally referred to as prudent behavior and the formation of fascinations that demonstrate such conduct. AI is an expansive concept that encloses a series of advances (a considerable lot of which have been being worked on for quite a few years) that are expected to use human-like insight to handle the problems. Right now in combination with enhanced AI developments like extreme or significantly more engaged, we are experiencing a renewed enthusiasm for AI, energized by a tremendous increase in computing capacity and a significantly greater increase in knowledge. AI, along with machine learning, can be used in computer vision. More advantages in the field of engineering as well as in medicine can be accomplished based on these future scenarios worldwide. Healthcare is seen as the next domain that is said to be altered by the use of the concept of artificial intelligence. The AI process is used for critical diseases such as cancer, neurology, cardiology and diabetes. The review includes the ongoing flow status of medical services for AI applications. A few progressive explorations of AI applications in medicinal services that provide a perspective on future where human interactions are gradually brought together by social insurance conveyance. Likewise, this review will discuss how AI and machine learning can save the life of someone. It is also a guide for healthcare professionals to see how, when, and where AI can be more efficient and have the desired outcomes.
Formulation and evaluation of medicated guava (Psidium guajava L.) wine using Saccharomyces crevices Var. HAU 1
Authors: Tamboli Firoj A , Mulani Sajid A , More Harinath N , Kolekar Yogesh S , Mali Nitin 
Published: June 2021

The present work encompasses production of wine from over ripe guava using Saccharomyces cerevisiae.The juices of guava were analyzed for pH, total Sugar, color, odour, test and reducing sugar. Guava is easy to culture. Guava & possess high nutritive value and its products like juices, beverages, nectars, spices etc. are largely appreciated by the consumers. Guava juice requires ‘capitalization’ so as to prepare a perfect wine out of it. Thus, the samples was fermented at 30 °C by using Saccharomyces cerevisiae. It was shown that guava juices having pH 4 yield higher alcohol as compare to samples having different pH. It was also seen that there was very less production of alcohol percentage. So, it improves the activity of wine.
Clinical and radio graphic evaluation of periotome in single rooted teeth
Authors: Kiran Kumar N , Slipa Hima , Murali Krishna T 
Published: June 2021

To evaluate the efficacy of periotome (Group p) in a traumatic extractions of single rooted teeth and to compare clinically and radio graphically with normal forceps extraction (Group c) in a sample of 30 patients. 30 patients -15 in each group (i.e. periotome and control group) were included in this randomised prospective comparative clinical study. Clinical parameters assessed were pain, buccal cortical plate fracture, gingival lacerations, soft tissue injury, teeth fracture, time taken for extraction, number and frequency of analgesics consumed and any post-operative complications were evaluated. Radiographic parameters of crestal alveolar bone levels were measured at pre operative, 1st month and 3rd month intervals by standardised IOPA using the grid in SOPRO imaging software, RVG.Comparing group C and P, statistically significant (p value &#60;0.05) amount of MCABL bone loss is seen between preoperative to 3rd month and from 1st month to 3rd month in periotome group. The periotome group showed gingival of grade 1. Fracture of buccal cortical plate was seen in 26%, 2 cases of teeth fracture. Patients in the control group had more pain and increased analgesics consumption.Extraction of single rooted teeth can be done by periotomeatr aumatically which gives better ridge contours for future prosthetic rehabilitation.
Work from home and changing dynamics
Authors: Banga Anshita , Mahajan Fiza 
Published: June 2021

COVID-19 has been the biggest crisis of our times. Never before has been the entire world and each and every individual been impacted at this scale but when impacts are large, changes are too. The fear of infection forced all of us to work remotely from our home. It was the test of our technology and a mass experiment of Work From Home (WFH). Our research study aims to explore the changing behavior and mentality towards WFH and gauge it's various physical, mental and social impacts. The research aims to study the differences in perception of WFH by different gender, income levels, education levels and age groups. We intend to explore if there is any relationship between travel time and WFH and reverse migration and WFH and further, if there is any room for the option of taking a pay cut. This research paper is based on extensive primary research survey on 100 participants conducted through Google Forms and the further analysis done through cross tabulation and graphical methods. The research sample was adequately representative of varied socioeconomic strata s and had significant people from both gender, different income and education levels. The research brought forward some interesting insights. More than 75% of workers want to continue with remote work at least some of the time. Youth dislikes hybrid and wants either completely remote or work from office. People in age group 25-40 are least willing to resort to only work from office and 41-60 are least willing to resort to remote work. Males prefer working from home more than females. Increase in income strongly increases the preference for hybrid work. Those who spend large amount of time in traveling strongly prefer work from home. Relocation is a favorable decision for most but pay cut isn’t an option. Work from home has improved productivity, relations, sleep and body but with a pinch of loneliness.
SMART LOCKDOWN STRATEGY, SECOND AND THIRD WAVES OF COVID-19 IN PAKISTAN: A POLITICAL DISCOURSE ANALYSIS
Authors: Afzal Hanan , Sibtain Masroor , Iqbal Zafar , Saleem Hina 
Published: June 2021

Purpose: The present study investigates the violations of SOPs regarding the spread of COVID19 during the political processional campaigns in the Gilgit Baltistan and Senate elections in Pakistan held just before the second and third waves of COVID-19. For instance, during the first wave Pakistani government employed a smart lockdown along with persuasive awareness campaign. However, in the second and third waves, it seemed that SOPs were not influential due to violations by politicians themselves.
Method: The researchers analyze the journalistic text both verbal and pictorial by employing the qualitative and interpretive paradigm to understand the policies and strategies of political parties in their political gatherings. Data regarding political campaigns have been collected from the print media through the purposive sampling technique. The secondary data has been collected from various research publications to establish the background.
Main Findings: The study analyzed political response to COVID-19 SOPs on the part of Pakistani political parties during the political campaigns in Gilgit Baltistan and senate elections. Referent pictures (see Figures), taken from authentic, official newspaper websites, showed that during ‘Political congregations and rallies’, individuals and politicians attended the events without requiring social distance and masks. Both the opposition and ruling party and their workers have taken approximately equal parts to violate the SOPs to gain political gains and benefits.
Application of the Study: The study suggests that the political parties would not conduct these types of political events that cause the spread of the virus, especially when it is considered a worldwide pandemic. The study would be both socially and politically beneficial for the organizations and groups to learn how a pandemic may affect the masses if precautionary measures are not followed adequately.
The Originality of the Study: According to the researchers' best knowledge, the research gap of the present study is contemporary and innovative, i.e., integrating the conceptual model of political discourse with political events.
DOES CORPORATE SOCIAL RESPONSIBILITY REDUCE INFORMATION ASYMMETRY?: EMPIRICAL EVIDENCE FROM PAKISTAN
Authors: Khan Naeem , Malik Qaisar Ali , Saghir Ahsen , Aslam Muhammad , Husnain Muhammad 
Published: June 2021

Purpose: The work empirically investigates the effect of corporate social responsibility (CSR) on information asymmetry (IA).
Methodology: For analysis, the study uses annual data ranging from 2007 to 2017, collected from the published reports of companies registered at the Pakistani equity market comprising the non-financial sector. An unbalanced panel of 257 companies with 2383 observations is analyzed using the generalized methods of moment (GMM) technique.
Main findings: In line with stakeholder's theory, results disclose a negative association between the variable of CSR and IA. It suggests that investing in CSR-related activities will reduce the asymmetry of information among managers and shareholders.
Application of the study: Findings of the study uncover the benefits of CSR in relation to IA that must be considered while formulating any strategy both at the governmental and corporate level. Government should facilitate corporations that engage in CSR work while firms must include CSR in their policy-making as it can significantly reduce information asymmetry.
Novelty/ originality of the study: This study provides a deep analysis in the form of behavioural association and the effect of CSR practices on information asymmetry in the context of the Pakistani non-financial sector. The study endorses the concept of CSR practices for the reduction of information asymmetry in Pakistani firms.
Caracterización fisicoquímica y compuestos bioactivos en el coco (Cocos nucifera L.) y su aceite: Efecto del cultivar y región de cultivo
Authors: Montoya Ballesteros Luz del Carmen 
Published: June 2021

La pulpa y aceite de coco son altamente valorados por los efectos sobre la salud, éstas propiedades son atribuidas a compuestos bioactivos, principalmente a los ácidos grasos de cadena media, compuestos fenólicos y vitamina E. La concentración de los compuestos bioactivos, depende del cultivar, las condiciones bióticas y abióticas de la zona de cultivo. Se determinó el efecto del cultivar y zonas productoras, sobre los compuestos bioactivos en el coco y su aceite. Se analizaron las propiedades fisicoquímicas y los perfiles de componentes bioactivos en cultivares cosechados en Guerrero, Alto Pacifico-saladita, Enano Verde, e Hibrido y de Yucatán, Alto Pacífico-2, Enano Verde. Se encontro que las propiedades fisicoquímicas son diferentes dependiendo de la región de cultivo y el cultivar. En relación al perfil de ácidos grasos principalmente los ácidos laúrico, mirístico y palmítico, en los cultivares y las regiones no hay diferencia, pero si en el contenido de compuestos fenólicos y a-tocoferol. El cultivar Enano Verde de Yucatán, es superior en el contenido de compuestos fenólicos (767.44 mg acido galico/100g), mientras que Alto Pacífico -Saladita en α-tocoferol ( 151.03µg/100g).Estos cultivares podrían significar un gran potencial en el contenido de compuestos fenólicos y α-tocoferol, además de los ácidos grasos de cadena media, en las regiones correspondientes.
Educação física escolar, corpo e linguagem
Authors: Machado Aline Gomes , Baptista Tadeu João Ribeiro 
Published: June 2021

Objetivo: O objetivo do presente estudo consiste em apresentar reflexões acerca da concepção de linguagem a partir dos estudos de Vygotsky, Luria, Leontiev e Bakhtin, além de dialogar sobre as relações entre corpo e linguagem à luz de diferentes matrizes teóricas, passando pelas contribuições de trabalhos da área de Educação Física. Método: Trata-se de um aprofundamento teórico, a partir da análise apresentada sobre o desenvolvimento do conceito de linguagem pelas diferentes matrizes teórica no campo da Educação Física. Resultados: Identifica-se a necessidade de verificar como a relação entre Educação Física e linguagem é compreendida no contexto escolar brasileiro e de que forma ela se dá na ação pedagógica. Considerações Finais: Compreender a Educação Física como linguagem representa um significativo avanço para a área, pois eleva as possibilidades de ensino sob um viés crítico, distanciando-o das práticas excludentes e mecanicistas que por muito tempo estiveram enraizadas no campo escolar.