bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of Healthy Aging Among Community Dwelling Adults Age 70 and Older From Five European Countries
Authors: Schietzel Simeon , Chocano-Bedoya Patricia O. , Sadlon Angelique , Gagesch Michael , Willett Walter C. , Orav Endel J. , Kressig Reto W. , Vellas Bruno , Rizzoli René , Silva José A. P. da , Blauth Michael , Kanis John A , Egli Andreas , Bischoff-Ferrari Heike A. 
Published: October 2021

Abstract
Background: To compare the prevalence of healthy aging among adults age 70 and older from 5 European countries recruited for the DO-HEALTH clinical trial. Participants were selected for absence of prior major health events. Methods: Cross-sectional analysis of DO-HEALTH baseline data. All 2,157 participants (mean age 74.9, SD 4.4; 61.7% women) were included and 2,123 had data for all domains of the healthy aging status (HA) definition. HA was assessed based on the Nurses` Health Study (NHS) definition requiring four domains: no major chronic diseases, no disabilities, no cognitive impairment (Montreal Cognitive Assessment, MoCA ≥25), no mental health limitation (GDS-5 <2, and no diagnosis of depression). Association between HA and age, BMI, gender, and physical function (sit-to-stand, gait speed, grip strength) was assessed by multivariate logistic regression analyses adjusting for center. Results: Overall, 41.8% of DO-HEALTH participants were healthy agers with significant variability by country: Austria (Innsbruck) 58.3%, Switzerland (Zurich, Basel, Geneva) 51.2%, Germany (Berlin) 37.6%, France (Toulouse) 36.7% and Portugal (Coimbra) 8.8% (p <0.0001). Differences in prevalence by country persisted after adjustment for age. In the multivariate model, younger age (OR = 0.95, 95% CI 0.93 to 0.98), female gender (OR = 1.36, 95% CI 1.03 to 1.81), lower BMI (OR = 0.94, 95% CI 0.91 to 0.96), faster gait speed (OR = 4.70, 95% CI 2.68 to 8.25) and faster performance in sit-to-stand test (OR = 0.90, 95% CI 0.87 to 0.93) were independently and significantly associated with HA. Conclusions: Despite the same inclusion and exclusion criteria preselecting relatively healthy adults age 70 years and older, HA prevalence varied significantly between countries and was highest in Austria and Switzerland, lowest in Portugal. Independent of country, younger age, female gender, lower BMI and better physical function were associated with HA.Trial registration: DO-HEALTH was registered under the protocol NCT01745263 at the International Trials Registry (clinicaltrials.gov), and under the protocol number 2012–001249-41 at the Registration at the European Commu-nity Clinical Trial System (EudraCT).
Controllable synthesis and adsorption mechanism of flower-like MoS2/g-C3N4 nanocomposites for removal of methylene blue in water
Authors: Wang Zhentao , Hasan Jaafar , Wang Jingjing , Zhang Caiwei , Iqbal Waheed , Chang Ninghui , Qin Chuanguang 
Published: October 2021

Abstract
The fabrication and adsorption mechanism of flower-like MoS2/g-C3N4 nanocomposites as new adsorbent materials were investigated by batch sorption experiments in this paper. The influence of factors such as pH, adsorbent dosage, concentration and temperature on the adsorption properties of flower-like MoS2/g-C3N4 nanocomposites were studied in detailed. The adsorption isotherm data was fitted with the Langmuir model, and the adsorption kinetic characteristics conform to the quasi second-order kinetic equation. Thermodynamic data showed that the adsorption process of methylene blue (MB) was feasible, endothermic and spontaneous. At 45 ℃, the maximum adsorption capacity was 278.4 mg/g. The adsorbed MB solution was used to water the wheat and chickpea plants within 15 days. Compared with MB solution, the treated MB solution made the plants grow much more better.
Comparative Chloroplast Genome Analyses of Ilex (Aquifoliaceae): Insights Into Evolutionary Dynamics and Phylogenetic Relationships
Authors: Xu Kewang , Lin Chenxue , Lee Shiou Yih , Mao Lingfeng , Meng Kaikai 
Published: October 2021

Abstract
BackgroundDespite many species of Ilex (Aquifoliaceae) are of horticultural importance and are widely grown in parks and gardens throughout the world for their foliage and decorative berries, limited genetic information has greatly hampered our understanding of the chloroplast genome evolution and phylogenetic relationships within the genus. This study attempted to address these problems by comparing the chloroplast genomes and analyzing phylogenetic relationships within the genus.ResultsIn this study, analyses of chloroplast genome structure, codon usage, GC content, gene rearrangement, nucleotide diversity, inverted repeats (IR) boundary, repeat sequence, and SSR component were conducted by comparing 41 chloroplast genomes of Ilex. The results showed that these Ilex chloroplast genomes were evolutionary conserved at the genome level and no rearrangement of the complete cp genome in the 41 Ilex genomes was recorded. On the contrary, there were still a few mutational hotspots identified from these chloroplast genomes, which were considered as hypervariable regions useful for future phylogenetic studies and DNA barcoding. Using the complete chloroplast genome sequences, we reconstructed a highly supported phylogeny of Ilex and well-resolved the complicated relationships among the different lineages within Ilex.ConclusionThe present study increased our understanding of the chloroplast genome evolution and phylogenetic relationships within Ilex. The availability of these genetic resources will be helpful for the future studies in DNA barcoding, species delimitation, phylogenetic reconstruction as well as the hybridization and introgression events between distantly related lineages within Ilex.
Comparative Analysis of Three Typical Cantilever Scaffold Supporting Systems
Authors: Geng Dajiang , Dai Ning , Zhang De , Jin Xuesheng , Long Minjian 
Published: October 2021

Abstract
In order to effectively guide the selection of scaffold in designing the cantilever scaffold, comprehensive analyses of three typical scaffold supporting systems (including fully cantilever, bottom-supporting cantilever and pull-up cantilever) are carried out. The calculation formulas of the internal force for the three scaffold supporting systems are proposed based on the theoretical analysis, which are effectively verified by the finite element method (FEM). In addition, the force mechanism and benefits of the three scaffold supporting systems are compared and analyzed combined with actual engineering. The results indicate that there is high calculating accuracy for the proposed internal force and deflection calculation formulas about the scaffold supporting systems. According to the distribution uniformity of the internal force and controlling of the deformation of the main girder, the bottom-supporting cantilever system is undoubtedly the best choice. While the pull-up cantilever supporting system is the best choice when considering the aspects of cost, construction period and social benefits, which ought to be popularized in engineering practice.
Title: Acute effects of self-myofascial release compared to dry needling on myofascial pain syndrome related outcomes: range of motion, muscle soreness and performance. A randomized controlled trial.
Authors: Vicente-Mampel J , Bautista IJ , López-Soler J , Torregrosa-Valls J , Gargallo P , Baraja-Vegas L 
Published: October 2021

Abstract
Objectives: myofascial pain syndrome (MPS) is associated with reductions in range of movement (ROM), decrease in physical function and performance and increase in pain in different populations. Elucidating the best prevention and treatment strategies for MPS has been one of the main goals in the last decade. The objective of the present study was to compare the acute effects of self-myofascial foam rolling (SFR) and dry-needling (DN) techniques on ankle dorsiflexion ROM, soreness post-needling and performance through countermovement jump (CMJ) height. Methods: a prospective crossover design composed by 12 active adults, aged 23.41 ± 1.68 years (weight: 78.33 ± 9.02 Kg; height: 1.79 ± 0.088 m) with active ankle dorsiflexion restriction was performed. Participants were randomized into the SFR and DN techniques to analyze its effects on ankle dorsiflexion ROM, muscle soreness and jump height at pre, post and 24 h post-intervention. Results: significant improvements were found by DN on ankle dorsiflexion at 24 hours post intervention and muscle soreness by SFR at the same time point. No significant differences were found between conditions. Conclusions: Both SFR and DN are effective in improving ankle dorsiflexion and performance in young adults without producing an acute effect in muscle soreness.
Intraepithelial Lymphocytes are Indicators of Better Prognosis in Surgically Resected Endometrioid-Type Endometrial Carcinomas at Early and Advanced Stages
Authors: Kono-Sato Takako , Miyai Kosuke , Yamagishi Yoji , Miyamoto Morikazu , Takano Masashi , Matsukuma Susumu , Sato Kimiya , Tsuda Hitoshi 
Published: October 2021

Abstract
Background: Tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) may be useful prognostic indicators in endometrial cancer. However, standardized assessment methods and the prognostic roles of these cells in different stage groups are unclear.Methods: Formalin-fixed paraffin-embedded tissue samples of 107 endometrioid-type endometrial carcinomas (EECs) comprising 60 stage IB and 47 stage IIIC or IVB cases were evaluated. CD3+ TILs, CD8+ TILs, CD68+ TAMs, and CD163+ TAMs were detected by immunohistochemistry, and their densities were evaluated by semiquantitative and quantitative methods. TILs within tumor epithelial cell nests (E-TILs) and those within the stroma at the invasive front (S-TILs) were evaluated separately for CD3+ and CD8+ cells. The “TIL score” was defined as the sum of semiquantitative scores of CD3+ E-TILs, CD3+ S-TILs, CD8+ E-TILs, and CD8+ S-TILs. For TAMs, the area of CD68+ and CD163+ cells in the invasive margin were semiquantitatively and quantitatively evaluated. Clinicopathological and prognostic implications of TILs and TAMs in stage IB and IIIC/IVB EECs were examined by Cox univariate and multivariate analyses.Results: By Cox univariate analyses, semiquantitatively low CD3+ E-TILs, low CD8+ E-TILs, and low “TIL score” were significantly correlated with worse prognosis in stage IB patients (P = 0.011, 0.040, and 0.039, respectively). Likewise, low CD3+ E-TILs and low CD8+ E-TILs, by both semiquantitative (P = 0.011 and 0.0051) and quantitative evaluations (P < 0.0001, and P = 0.0015) and low “TIL score” (P = 0.020) were significantly correlated with worse prognosis in stage IIIC/IVB patients. By Cox multivariate analyses, semiquantitatively low CD3+ E-TILs in stage IB (P = 0.030) and semiquantitatively low CD3+ E-TILs or “TIL score” in stage IIIC/IVB (P = 0.022 and 0.049, respectively) were independent worse prognostic factors. CD68+ or CD163+ TAMs were not correlated with prognosis in any patients.Conclusions: Semiquantitatively low E-TILs, possibly representing low degree of TILs, are correlated with prognosis in both early and advanced stage patients with EEC. In particular, CD3+ E-TILs and CD8+ E-TILs are potentially useful prognostic markers in patients with EEC regardless of the stage.
Developmental Outcomes of Very Low Birth Weight Infants with Catch-up Head Growth: A Nationwide Cohort Study
Authors: Hong You Mi , Cho Dong Hue , Kim Jin Kyu 
Published: October 2021

Abstract
This study aims to determine demographic or perinatal characteristics in premature infant according to head growth, identify clinical factors affecting growth catch-up, and find differences in developmental outcomes according to catch-up states based on Korean Neonatal Network (KNN) data. This nationwide prospective cohort study of Korean Neonatal Network (KNN) data analyzed premature infants with very low birth weight (< 1,500 g) between 2014 and 2017. A total of 253 eligible infants who had completed Bayley scales of infant and toddler development (BSID) 3rd were assigned into two groups: a catch-up (CU) group with head circumference above the 10th percentile and a no catch-up (NCU) group with head circumference below the 10th percentile at 18-24 months of corrected age (CA). Most (81.4%, 203/253) premature infants exhibited catch-up growth at 18-24 months of CA. Rates of microcephaly, intraventricular hemorrhage (IVH), bronchopulmonary dysplasia (BPD), sepsis, necrotizing enterocolitis (NEC), length of NICU stay, ventilation care, and parenteral nutrition were significantly greater in the NCU group (P < 0.05). On multiple linear regression analysis, the BPD status was the most clinical factor affecting catch-up head growth after adjusting for gestational age, birth weight, and birth head circumference (adjusted OR 4.586, 95% CI 1.960-10.729)At 18-24 months of CA, the NCU group exhibited lower developmental indices and higher rate of developmental delay than the CU group. Motor developmental delay was the most significant factor relevant to catch-up head growth and the motor development index difference between the two groups was only statistically significant after adjusting for four major neonatal morbidities: IVH, BPD, sepsis, and NEC status (adjusted OR 10.727, 95% CI 1.922-59.868). Thus, the developmental outcome of very low birth weight (VLBW) infants at 18-24 months of CA might be dependent on whether head growth was caught up. Key clinical factors determining the catch-up status were BPD and NEC status, length of parenteral nutrition, and ventilator care. Thus, measurements of head circumference at 18-24 months of CA can predict developmental delays of VLBW infants.
Comparative Analysis of The Daily Brain Transcriptomes of Asian Particolored Bat
Authors: Zhang Guoting , Chu Yujia , Jiang Tinglei , Li Jingjing , Feng Lei , Wu Hui , Wang Hui , Feng Jiang 
Published: October 2021

Abstract
Circadian rhythms are found in almost all organisms, and they comprise one of the most basic characteristics of living things. Bats have attracted interest from researchers because of their unique biological rhythms. However, little is known about the molecular underpinnings of circadian signaling in bats. In this study, we used RNA-Seq to uncover the rhythms of expressed genes and biological processes in the brains of Asian particolored bats. Four collected time points corresponding to four biological states, rest, sleep, wakefulness, and active, were selected over the 24-hour day, and six comparisons of differentially expressed genes were obtained. Downstream functional enrichment analyses suggested that different physiological processes were active at various biological states, including drug metabolism, signaling pathways, and the circadian clock. Furthermore, trend analysis suggested that groups of genes are significantly clustered and are expressed at the lowest levels during the sleep state while being highly expressed during the active stat. In addition, we also identified the Per2 locus as an important circadian clock gene in the brain of Asian particolored bat. Our study provides a new overview of the molecular basis underlying the circadian clock in the brain of bats.
Methane Super-Emitters in California’s Oil Fields
Authors: Vafi Kourosh , Rafiq Talha , Biraud Sebastien , Thorpe Andrew , Duren Riley , Hopkins Francesca 
Published: October 2021

Abstract
Methane is a potent yet underestimated contributor to global greenhouse gas emissions. We examined the characteristics of 255 sources of methane super-emitters identified by NASA’s Airborne Visible/InfraRed Imaging Spectrometer-Next Generation in 109 California oil fields. Super-emitter events were primarily associated with oil & gas wells, gas gathering pipelines, and storage tanks (73% of sources). Sources with persistence of <=20% and > 50% comprised 77% and 1% of sources and contributed to 59% and 4% of the total measured emissions, respectively. We estimate total onsite methane emissions from 24 oil fields as 2.3 to 3.4 times the estimated rate by the current official lifecycle assessment model for California’s Low Carbon Fuel Standard used for determining carbon intensity of crude oil production. These findings suggest that without considering direct observations of oil field methane super emitters, greenhouse gas emissions policy for the oil and gas sector is likely to underestimate emissions.
Outcomes of Periodontal Treatment in Diabetes Mellitus Patients at Kiruddu Referral Hospital in Uganda. A Prospective Cohort Study
Authors: Kiryowa Haruna , Mwaka Erisa , Buwembo William , Munabi Ian , Rwenyonyi Charles , Kaddumukasa Mark 
Published: October 2021

Abstract
Introduction: Periodontitis is a common complication of diabetes mellitus associated with poor glycemic control. The relationship between periodontal disease and glycemic control in patients with diabetes mellitus remains unclear. This study set out to determine the outcomes of periodontal treatment in diabetic patients in Uganda. Methods: Using a cohort study design, 41 adult diabetic patients with periodontal disease were enrolled and followed up for 3 months. Fasting blood sugar, glycated hemoglobin levels, pocketprobing depth, bleeding and clinical attachment loss at baseline and 3 months after periodontal treatment were determined. Gingival crevicular fluid was assessed to detect presence of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Bacteroides forsythus and Fusobacterium nucleatum. Data were analyzed using R version 4.10. Mean differences were calculated to determine effect of treatment and multiple logistic regressions was used to determine association between Hba1c and the different variables.Results: Of the41 participants, 61% were females while 39% were males. The average age was 49.2 years (S.D = 11.2)while the mean BM1 was 27.8 (S.D = 4.8). Overall, there was a reduction in the average number of teeth with bleeding sites, those with pockets and the frequencies of selected bacteria except Fusobacterium nucleatum at 3 months after periodontal treatment. Following periodontal treatment, 39% of the participants had an improvement in their glycemic control (mean HbA1c reduction of 1.86) with age < 47.1 years, diabetic duration less than 1.6 years, BM1< 27.7 and HBA1c >8.9 at baseline being positively associated with this improvement. Conclusion: Treating periodontal disease in diabetic patients especially those with HBA1c <9.0 can improve glycemic control. However, larger studies need to be conducted to ascertain why some patients fail to attain an improved metabolic control following this intervention.
Inner Wall Temperature Distribution Measurement of The Ladle Based on Cavity Effective Emissivity Correction
Authors: Liu Jun , Huang Yanhui , Ci Ying , Fang Jiangxiong , Yang Feng , Nobes David 
Published: October 2021

Abstract
Inner wall temperature of ladle is closely related to the quality of steelmaking and control of steel-making tapping temperature. This article adopts a rotating platform to drive an infrared temperature sensor and a laser sensor to scan the temperature field distribution of the ladle inner wall at the hot repair station, where the scanning laser sensor obtains coordinates of each measured point. Because of measuring errors of infrared thermal radiation caused by emissivity uncertainty of the ladle inner wall surface, this article proposes a method for temperature measurement based on Monte Carlo model for effective emissivity correction of each measured point. In the model, we consider the ladle and fire baffle as a cavity. By calculation of the model, the effect of distance from the fire baffle to the ladle and the material surface emissivity of the ladle inner wall on the effective emissivity of the cavity are obtained. After that, the effective emissivity of each measured point is determined. Then the scanning temperature of each measured point is corrected to real temperature. By field measuring test and verification contrast, the results show that: the maximum absolute error of the method in this article is 4.7℃, the minimum error is 0.6℃, and the average error is less than 2.8℃. The method in this article achieves high measurement accuracy and contributes to the control of metallurgical process based on temperature information.
New species, synonymies, combinations, and records of micropterous Athetini from China (Coleoptera: Staphylinidae: Aleocharinae)
Authors: Assing Volker 
Published: October 2021

Two micropterous and locally endemic species of Bellatheta Roubal, 1928 and four of Atheta Thomson, 1858, subgenus Microdota Mulsant & Rey, 1873, from China are described and illustrated: Bellatheta qiliana spec. nov. (Qinghai, Gansu); B. aucticeps spec. nov. (Yunnan: Gaoligong Shan); Atheta (Microdota) clarata spec. nov. (Yunnan: Gaoligong Shan); A. (M.) minica spec. nov. (Sichuan: Songpan env.); A. (M.) qinlingica spec. nov. (Shaanxi: Qinling Shan); A. (M.) biformis spec. nov. (Gaoligong Shan). New illustrations are provided for two previously described Microdota species. One genus-group and one species-group synonymy are proposed: Bellatheta Roubal, 1928 = Oroekklina Pace, 1999, syn. nov.; Atheta (Microdota) amischoides Assing, 2006 = A. (M.) wuliangensis Pace, 2017, syn. nov. Five new combinations are proposed: Bellatheta daxuensis (Pace, 1999), comb. nov., B. excaecata (Assing, 2009), comb. nov., B. proiecta (Assing, 2002), comb. nov., B. smetanai (Pace, 2004), comb. nov. (all of them previously in Oroekklina), and Franzidota geostiboides (Assing, 2011), comb. nov. (ex Platyola Mulsant & Rey, 1875). Additional records of two species of Bellatheta and of five species of Microdota are reported from China. Catalogues of the Bellatheta species and the micropterous Microdota species recorded from China are provided. Including the new species and synonymies, 15 species of Bellatheta, seven of them micropterous, and 85 of Microdota, 19 of them micropterous, have been reported from China. The Microdota fauna of Taiwan is composed of 13 species, four of them micropterous. The distributions of the micropterous Bellatheta species of China are mapped.
Taxonomic acts
Bellatheta qiliana spec. nov. – urn:lsid:zoobank.org:act:F391FF78-2A4B-4BEA-BB85-85AC8E30FE70Bellatheta aucticeps spec. nov. – urn:lsid:zoobank.org:act:1A3E6AAA-2C3C-44B8-A911-4F1246774075Atheta clarata spec. nov. – urn:lsid:zoobank.org:act:EE3C4E47-FEAB-413A-81C7-A063529A5235Atheta minica spec. nov. – urn:lsid:zoobank.org:act:E325AF25-C1DD-441C-B7D5-AB2ACF109581Atheta qinlingica spec. nov. – urn:lsid:zoobank.org:act:1590B986-DE95-458C-AFE3-71CC51AB4106Atheta biformis spec. nov. – urn:lsid:zoobank.org:act:30A8940E-5B8A-4E27-997F-777E8FFF3E80
Pilot study on the treatment of lake water with algae by ultrafiltration–ozone–biologically activated carbon
Authors: Xu Pengcheng , Chen Yan , Gui Bo , Guo Xiaolong , Zhang Jian 
Published: October 2021

Abstract
For the treatment of lake water with algae, the coagulation–ultrafiltration–ozone–biologically activated carbon (CUF–O3–BAC) integrated process was first used to treat East Taihu Lake water in China, aiming at evaluating the removal efficiencies of algae, permanganate index (CODMn), UV254, NH3-N and disinfection by-products (DBPs) precursors. In addition, the long-term performance of the membrane operation under the fluxes of 60, 70, 80 and 90 L/(m2·h) was also investigated, and kinetic models were established. The experimental results showed that the integrated process had positive impaction of algae, CODMn, UV254 and NH3-N removal, and the removal rates were 95.89 ± 1.52, 76.18 ± 4.38, 72.06 ± 4.72 and 81.31 ± 6.71%, respectively. The CUF process was prone to increase the formation potentials of DBPs. Although ozone could reduce the formation risks of chlorinated trihalomethanes (THMs) to a certain extent, it is ineffective to reduce those of brominated THMs and haloacetic acids (HAA5). However, the CUF–O3–BAC process was an effective technology for the removal of THMs and HAA5 precursors in drinking water treatment. Finally, it was found that the relationship between transmembrane pressure (TMP) and time conformed to the first-order and second-order kinetic models, and the linear fitting coefficients were all above 90%.