bluuebunny/crossref_metadata_2025_split huggingface dataset:
Digitalisierung der Arbeitswelt kommunaler Energieversorger
Authors: Borchert Margret , Martinetz Simone , Bienzeisler Bernd , Mohr Olaf , Fregin Marie-Christine , Roth Ines , Becker Sascha , Schmidt Katharina , Straub Matthias , Troch Sonja Luise 
Published: February 2021

ZusammenfassungZiel des Verbundprojekts AKTIV-kommunal war die Entwicklung, pilothafte Umsetzung und Evaluierung einer integrierten Toolbox für die digitale Transformation kommunaler Energieversorger. In drei integriert bearbeiteten Teilprojekten standen die Digitalisierung von Arbeitsprozessen, digitale Arbeitsmodelle sowie Digital Leadership im Mittelpunkt der Projektaktivitäten. Dabei bildeten jeweils ein Forschungspartner und ein Anwendungsunternehmen ein Tandem, um zu wissenschaftlich fundierten und praxistauglichen Ergebnissen zu gelangen. Der Projektbeirat, dem namhafte Vertreter/-innen aus Unternehmen, von Verbänden, der Sozialpartner und weitere Wissenschaftler angehörten, gab zusätzliche Impulse für die Projektarbeit. Im vorliegenden Beitrag werden die zentralen Ergebnisse von AKTIV-kommunal vorgestellt. Darüber hinaus werden Hinweise zu den im Projektverlauf erstellten Transfermaterialien gegeben und erfolgt ein Ausblick auf zukünftige Forschungsaktivitäten.
DigiTraIn 4.0: Ein Beratungskonzept für die Transformation in eine digitale Arbeitswelt
Authors: Kaiser Stephan , Kozica Arjan , Littig Bianca , Müller Madlen , Rauch Ricarda , Thiemann Daniel 
Published: February 2021

ZusammenfassungDas Projekt DigiTraIn 4.0 hat ein Beratungskonzept entwickelt und erprobt, das Unternehmen bei der erfolgreichen Digitalisierung ihrer Arbeitswelt unterstützt. Das Beratungskonzept basiert auf vier anwendungsorientierten Instrumenten: Der Digitalisierungsatlas bildet die Digitalisierung der Arbeitswelt in all ihren Dimensionen ab und ermöglicht es, die Notwendigkeit sowie Chancen und Risiken der Veränderungen zu verstehen. Hierauf aufbauend können Unternehmen mit dem Digitalisierungsindex ihren aktuellen Ist-Digitalisierungsgrad der Arbeitswelt individuell bestimmen. Der individuelle Digitalisierungsgrad dient als Ausgangspunkt für den Digitalisierungskompass, der es dem Unternehmen ermöglicht, die Soll-Vorstellung der digitalen Arbeitswelt zu illustrieren und eine unternehmensspezifische Transformationsagenda abzuleiten. Der Beratungsprozess und die Entwicklung der zentralen Instrumente werden in diesem Beitrag dargestellt.
Game of Roster – GamOR
Authors: Blaudszun-Lahm Annette , Kubek Vanessa , Meyer auf’m Hofe Harald , Schlicker Nadine , Velten Sebastian , Uhde Alarith 
Published: February 2021

ZusammenfassungDer Pflegeberuf wird als wenig attraktiv wahrgenommen: physische Belastungen, Schichtdienst, vergleichsweise geringes Gehalt sind – neben weiteren Faktoren – dafür ausschlaggebend. Negative Auswirkungen von Schichtarbeit können dadurch reduziert werden, dass das Autonomieerleben der Mitarbeitenden erhöht wird. Ziel ist, dass sie nicht weiter das Gefühl haben, dass (neben ihrem Berufsleben auch) über ihr Privatleben verfügt wird. Pflegekräfte selbst sollen gestalten. Diesen Gestaltungsspielraum adressiert das Verbundprojekt GamOR: mithilfe einer kollaborativen, d. h. gemeinschaftlichen, und zugleich digitalisierten Dienstplanung soll die Autonomie und damit auch die Zufriedenheit der Pflegekräfte erhöht werden.
Digitalisierung der Arbeit in der ambulanten Pflege
Authors: Bleses Peter , Breuer Jens , Busse Britta , Friemer Andreas , Jahns Kristin , Kludig Rebecca , Raudies Stephanie 
Published: February 2021

ZusammenfassungDie Digitalisierung dringt mit der Einführung digitaler Tourenbegleiter in die ambulante Pflege in die Arbeit von Pflegekräften vor, die zuvor meist noch wenig Erfahrung mit digital gestützter Arbeit hatten. Pflegearbeit ist hier durch eine berufskulturelle Prägung gekennzeichnet, deren Kern in der persönlichen Interaktionsbeziehung liegt. Um digitale Technik erfolgreich in die ambulante Pflege einführen zu können, ist ihre Integrationsfähigkeit in die Pflegearbeit aus Perspektive der Pflegekräfte zentral: Digitale Technik sollte Pflegearbeit unterstützen, darf sie aber nicht stören oder mit guter Pflege unvereinbar sind. Und v. a. sollte die Digitalisierung der Pflegearbeit angesichts zunehmend belastender Arbeitsbedingungen auch die Arbeitsqualität der Pflegekräfte verbessern. Das Verbundprojekt KoLeGe hat in der ambulanten Pflegepraxis Lösungen erarbeitet, wie digitale Tourenbegleiter unter Berücksichtigung der Bedarfe von Pflegekräften gut in die Praxis eingeführt werden können.
Entwicklung eines digitalen Lehr- und Lernarrangements für das deutsche Handwerk
Authors: Spieth Patrick , Klos Christoph , Röth Tobias , Schmidt Ludger , Funk Johannes , Klingauf Anna , Robak Steffi , Knaut Moritz , Klimpel Maria , Heidemann Lena , Schüttler Friedrich , Gringel Heiko 
Published: February 2021

ZusammenfassungDas BMBF/ESF Projekt FachWerk entwickelte während der dreijährigen Projektlaufzeit ein multimediales Lehr- und Lernarrangement zur Adoption von Informations- und Kommunikationstechnologien im deutschen Handwerk. Ziel ist die digitalisierte Fachkräftequalifizierung für die zukünftige Arbeitswelt. Im Rahmen des Projekts wurden verschiedene Mega- und Technologietrends sowie Erfolgsfaktoren identifiziert, Bedarfe für zukünftige Qualifikationen definiert, ein konkretes Lehrkonzept gestaltet und darauf basierend die digitale Lehr- und Lernplattform entwickelt, getestet und evaluiert. Die nachhaltige Verwertung der Plattform wird durch assoziierte Partner langfristig sichergestellt. Die Plattform dient somit als ein wichtiger Schritt zur digitalen Transformation des Handwerks.
Digitalisierung und Arbeitsorganisation
Authors: Holst Hajo , Metternich Joachim , Schwarz-Kocher Martin , Ardelt Thomas , Brunsen Hendrik , Kalff Yannick , Kleine Nadine , Kutlu Yalcin , Meißner Alyssa , Müller Marvin , Niehoff Steffen , Seibold Bettina , Sinopoli Robert 
Published: February 2021

ZusammenfassungTeamWork 4.0 beschäftigt sich mit der Einführung von digitalen Assistenzsystemen und ihren Rückwirkungen auf industrielle Gruppen- und Teamarbeit. Die in den Verbundunternehmen entwickelten und erprobten Assistenzsysteme adressieren jeweils Shopfloor-Herausforderungen, die in industriellen KMU weit verbreitet sind: Das bei der Mahr GmbH entwickelte digitale Dokumentationssystem macht die aus der kundenindividuellen Maschinenfertigung erwachsende Komplexität an Dokumentationen beherrschbar, die bei der Homag AG entwickelte KVP-App erleichtert die Beteiligung der Mitarbeitenden an Verbesserungsprozessen und das bei der Voith AG eingeführte Shopfloor Management-System erhöht die Transparenz von Problemlösungen. Der von TeamWork 4.0 verfolgte beteiligungsorientierte Ansatz stellt sicher, dass die Assistenzsysteme in der Belegschaft über eine hohe Akzeptanz verfügen und die Weiterentwicklung der bestehenden Gruppen- und Teamarbeit unterstützen.
Holographic and localization calculations of boundary F for $$ \mathcal{N} $$ = 4 SUSY Yang-Mills theory
Authors: Van Raamsdonk Mark , Waddell Chris 
Published: February 2021

Abstract
$$ \mathcal{N} $$
N
= 4 Supersymmetric Yang-Mills (SYM) theory can be defined on a half-space with a variety of boundary conditions preserving scale invariance and half of the original supersymmetry; more general theories with the same symmetry can be obtained by coupling to a 3D SCFT at the boundary. Each of these theories is characterized by a quantity called “boundary F”, conjectured to decrease under boundary renormalization group flows. In this paper, we calculate boundary F for U(N) $$ \mathcal{N} $$
N
= 4 SYM theory with the most general half-supersymmetric boundary conditions arising from string theory constructions with D3-branes ending on collections of D5-branes and/or NS5-branes. We first perform the calculation holographically by evaluating the entanglement entropy for a half-ball centered on the boundary using the Ryu-Takayanagi formula in the dual type IIB supergravity solutions. For boundary conditions associated with D3-branes ending on D5 branes only or NS5-branes only, we also calculate boundary F exactly by evaluating the hemisphere partition function using supersymmetric localization. The leading terms at large N in the supergravity and localization results agree exactly as a function of the t’ Hooft coupling λ.
Additive manufacturing of biomorphic scaffolds for bone tissue engineering
Authors: Caiazzo Fabrizia , Alfieri Vittorio , Bujazha Brahim David 
Published: February 2021

AbstractBone tissue engineering has evolved owing to new opportunities of deep customisation offered by additive manufacturing technologies. Gyroid structures, which have been widely used for energy absorption or chemical catalysis, are now being employed as biomorphic structures as well to provide customer-oriented scaffolds for missing or injured bones. Unfortunately, limited data in terms of manufacturability and mechanical properties are available in the literature to support a wide application scope, because the bone to match is strongly dependent on the individual. Therefore, the study aimed at addressing this lack of knowledge, assessing the manufacturability of metal gyroids and further developing the correlation of the structural response with the designed geometry, so to allow the designer to provide the proper biomorphic structure on a case-by-case basis. Biocompatible steel was used to manufacture samples via laser powder-bed fusion; their elastic moduli and yield strengths were evaluated as a function of the orientation of the elementary cells, the symmetry and the wall thickness based on compression testing. Grounds have been given to support potential applications for tibias and vertebras.
External financial dependence and firms’ crisis performance across Europe
Authors: Eppinger Peter S. , Neugebauer Katja 
Published: February 2021

AbstractHow do financial market conditions affect real economic performance? Empirical investigations of this question have often relied on measures of external financial dependence (EFD) that are constructed using US data and applied to other countries under the assumption of a stable industry ranking across countries. This paper exploits unique, comparable survey data from seven European countries to show that correlations of EFD across countries are weak, casting some doubt on this assumption. We then use the novel survey-based EFD index to show that the global financial crisis had a disproportionately negative impact on the real performance of financially dependent firms. Further investigations highlight the importance of supply chains in propagating the credit shock.
Derivation of the Landau–Pekar Equations in a Many-Body Mean-Field Limit
Authors: Leopold Nikolai , Mitrouskas David , Seiringer Robert 
Published: February 2021

AbstractWe consider the Fröhlich Hamiltonian in a mean-field limit where many bosonic particles weakly couple to the quantized phonon field. For large particle numbers and a suitably small coupling, we show that the dynamics of the system is approximately described by the Landau–Pekar equations. These describe a Bose–Einstein condensate interacting with a classical polarization field, whose dynamics is effected by the condensate, i.e., the back-reaction of the phonons that are created by the particles during the time evolution is of leading order.
Mineralogical, chemical and stable C and O isotope characteristics of surficial carbonate structures from the Mediterranean offshore Israel indicate microbial and thermogenic methane origin
Authors: Spiro Baruch , Ezra Oded , Najorka Jens , Delgado Antonio , Bialik Or , Ben-Avraham Zvi , Coleman Dwight , Makovsky Yizhaq 
Published: February 2021

AbstractThe Eastern Mediterranean continental slope offshore Israel became a focus of exploration for, and production of, natural gas in recent years. The 2010–2011 Nautilus ROV expedition performed detailed video recordings and sampling in two areas offshore Israel: the Palmachim disturbance, southwest of Tel Aviv, and an area offshore Acre, north of Haifa. An analytical programme regarding the carbonate structures was carried out, examining the overall mineralogy, stable C and O isotopes, and Ca, Mg, and Mn concentrations. This provided information on their composition and as a result, an indication of the carbon sources and temperature of formation. The major authigenic minerals identified comprised magnesian calcite, dolomite, aragonite, and kutnohorite. The detrital minerals included quartz, clays, feldspars, and rare augite and enstatite, likely transported from the Nile estuary. The carbon isotope composition of aliquots taken from nineteen samples from these areas have an overall δ13C range from −62.0 to −0.1‰PDB, indicating a range of microbial/biogenic and thermogenic methane contributions. The range of δ18O from 2.7 to 7.0‰PDB reflects the range of temperatures of formation. The δ18O characteristics differ among areas. In general, high values; δ18O >5‰PDB are recorded from area N2 of the Palmachim disturbance, indicating low temperature of formation. Low values of δ18O (<5‰PDB) were measured from areas W2 and W3 of the Palmachim disturbance, together with samples from area N2 of the Palmachim disturbance, and samples from areas A1 and A2 offshore Acre indicate high temperature origin. Samples from an inactive chimney from area N2 range from pure dolomite to pure magnesian calcite. This trend is linked to δ13C increase from −39.9 to −0.1‰(PDB), and δ18O decrease from 6.2 to 4.7‰(PDB). These values indicate a decrease in the methane-derived carbon contribution and an increase in temperature. Kutnohorite, Ca(Mn2+, Mg, Fe 2+)(CO3)2 is a major component in samples from Acre, and less so in the Palmachim disturbance. An exploratory investigation of the relationship between Mn/Ca, δ18O and δ13C revealed that samples having Mn/Ca < 0.1(wt./wt.) have δ13C<−50‰PDB indicating a microbial methane source, while samples with Mn/Ca > 0.1 have δ13C between −35 and −22‰PDB suggesting a thermogenic origin. These results suggest that the mineralogical, isotopic δ13, δ18O, and chemical (Mn/Ca indicative of kutnohorite) characteristics of surficial carbonate structures can indicate and distinguish between deep and shallow methane sources in the Eastern Mediterranean.
Critical appraisal of the 2020 ESC guideline recommendations on diagnosis and risk assessment in patients with suspected non-ST-segment elevation acute coronary syndrome
Authors: Giannitsis Evangelos , Blankenberg Stefan , Christenson Robert H. , Frey Norbert , von Haehling Stephan , Hamm Christian W. , Inoue Kenji , Katus Hugo A. , Lee Chien-Chang , McCord James , Möckel Martin , Chieh Jack Tan Wei , Tubaro Marco , Wollert Kai C. , Huber Kurt 
Published: February 2021

AbstractMultiple new recommendations have been introduced in the 2020 ESC guidelines for the management of acute coronary syndromes with a focus on diagnosis, prognosis, and management of patients presenting without persistent ST-segment elevation. Most recommendations are supported by high-quality scientific evidence. The guidelines provide solutions to overcome obstacles presumed to complicate a convenient interpretation of troponin results such as age-, or sex-specific cutoffs, and to give practical advice to overcome delays of laboratory reporting. However, in some areas, scientific support is less well documented or even missing, and other areas are covered rather by expert opinion or subjective recommendations. We aim to provide a critical appraisal on several recommendations, mainly related to the diagnostic and prognostic assessment, highlighting the discrepancies between Guideline recommendations and the existing scientific evidence.
High risks of failure observed for A1 trochanteric femoral fractures treated with a DHS compared to the PFNA in a prospective observational cohort study
Authors: van der Sijp Max P. L. , de Groot Marianne , Meylaerts Sven A. , du Pré Karel J. , Verhage Sander M. , Schipper Inger B. , Niggebrugge Arthur H. P. 
Published: February 2021

Abstract
Introduction
Both the DHS and the PFNA are common and well-studied treatment options for stable trochanteric fractures. The aim of the current study was to compare the implant failure rates of these two implants in 31A1 type trochanteric femoral fractures.

Materials and methods
A single-centre observational cohort study was conducted in the Hip Fracture Unit of a multicentre level 1 trauma teaching hospital between December 2016 and October 2018. Patients with an AO/OTA type 31A1 fracture were included. Pathological fractures, bilateral fractures, high-energy traumas and patients younger than 18 years of age were excluded. Surgery was performed using either a DHS or PFNA. Both were used routinely for stable trochanteric fractures, and allocation was decided by the surgeon performing the operation. The primary outcome of this study was the implant failure rate in the first postoperative year. Secondary outcomes included the reoperation rate, functional recovery, pain and morphine use.

Results
Data were available from 126 patients treated with a DHS (n = 32, 25.4%) or PFNA (n = 95, 74.6%). Minor differences were observed in the patient characteristics including the prevalence of cognitive impairment (18.8% vs 40.2%; P = 0.028), prefracture independence in activities of daily living (87.1% vs 67.4%; P = 0.034) and prefracture mobility (independently without aides: 61.3% vs 40.4%; P = 0.033). Fractures treated with a DHS showed 25% implant failures, compared to 1.1% for fractures treated with a PFNA (P = 0.004). No differences were observed in any of the secondary outcomes.

Conclusions
Significantly more implant failures were observed for the DHS compared the PFNA within 1 year after surgery. Despite the fact that this did not result in differences in revision surgery, we conclude that the PFNA, considering the minimal number of implant-related fractures is a viable implant for A1 type trochanteric fractures.
TERT promoter mutations in penile squamous cell carcinoma: high frequency in non-HPV-related type and association with favorable clinicopathologic features
Authors: Kim Sang Kyum , Kim Jang-Hee , Han Jae Ho , Cho Nam Hoon , Kim Se Joong , Kim Sun Il , Choo Seol Ho , Kim Ji Su , Park Bumhee , Kwon Ji Eun 
Published: February 2021

Abstract
Purpose
Penile carcinoma is a rare malignant neoplasm with a largely unknown molecular pathogenesis. Telomerase reverse transcriptase promoter (TERT-p) mutations have been detected in several types of human malignancies. The aim of this study was to investigate the presence of TERT-p mutations in penile squamous cell carcinomas (SCCs) and their associations with clinicopathologic features.

Methods
In this retrospective study, Sanger sequencing was performed to detect TERT-p mutations in formalin-fixed paraffin-embedded tissue samples from 37 patients with penile SCC, 16 patients with cutaneous SCC, and 4 patients with non-neoplastic penile/skin tissue. The expression of p16INK4a and Ki-67 was investigated via immunohistochemistry. Associations of TERT-p mutation with clinicopathological factors, immunohistochemical results, and clinical outcome were statistically analyzed.

Results
Recurrent TERT-p mutations were identified in 18 out of 37 (48.6%) penile SCCs, including all 3 carcinoma in situ cases. TERT-p mutations were significantly more frequent in non-human papilloma virus (HPV)-related penile SCC types than in non-HPV-related penile SCC based on both histologic classification and p16INK4a immunoreactivity. Furthermore, TERT-p mutation was associated with a low histologic grade, low mitotic count, absence of necrosis, low Ki-67/MIB-1 labeling index, and absence of lymph node or distant metastasis.

Conclusion
Our study shows TERT-p mutations are the most frequent somatic mutations in penile SCC. In addition, TERT-p mutations are far more frequent in non-HPV-related penile SCC than in HPV-related penile SCC, indicating TERT-p mutations may have a role in tumorigenesis distinct from HPV-related penile SCC.
Graph Reconstruction from Unlabeled Edge Lengths
Authors: Garamvölgyi Dániel , Jordán Tibor 
Published: February 2021

AbstractA d-dimensional framework is a pair (G, p), where $$G=(V,E)$$

G
=
(
V
,
E
)

is a graph and p is a map from V to $$\mathbb {R}^d$$

R

d

. The length of an edge $$uv\in E$$

u
v
∈
E

in (G, p) is the distance between p(u) and p(v). The framework is said to be globally rigid in $$\mathbb {R}^d$$

R

d

if every other d-dimensional framework (G, q), in which the corresponding edge lengths are the same, is congruent to (G, p). In a recent paper Gortler, Theran, and Thurston proved that if every generic framework (G, p) in $$\mathbb {R}^d$$

R

d

is globally rigid for some graph G on $$n\ge d+2$$

n
≥
d
+
2

vertices (where $$d\ge 2$$

d
≥
2

), then already the set of (unlabeled) edge lengths of a generic framework (G, p), together with n, determine the framework up to congruence. In this paper we investigate the corresponding unlabeled reconstruction problem in the case when the above generic global rigidity property does not hold for the graph. We provide families of graphs G for which the set of (unlabeled) edge lengths of any generic framework (G, p) in d-space, along with the number of vertices, uniquely determine the graph, up to isomorphism. We call these graphs weakly reconstructible. We also introduce the concept of strong reconstructibility; in this case the labeling of the edges is also determined by the set of edge lengths of any generic framework. For $$d=1,2$$

d
=
1
,
2

we give a partial characterization of weak reconstructibility as well as a complete characterization of strong reconstructibility of graphs. In particular, in the low-dimensional cases we describe the family of weakly reconstructible graphs that are rigid but not redundantly rigid.
Consensus guidelines for botulinum toxin therapy: general algorithms and dosing tables for dystonia and spasticity
Authors: Dressler Dirk , Altavista Maria Concetta , Altenmueller Eckart , Bhidayasiri Roongroj , Bohlega Saeed , Chana Pedro , Chung Tae Mo , Colosimo Carlo , Fheodoroff Klemens , Garcia-Ruiz Pedro J. , Jeon Beomseok , Jin Lingjing , Kanovsky Petr , Milanov Ivan , Micheli Federico , Orlova Olga , Pandey Sanjay , Pirtosek Zvezdan , Relja Maja , Rosales Raymond , Sagástegui-Rodríguez José Alberto , Shahidi Gholam Ali , Timerbaeva Sofia , Wan Xinhua , Walter Uwe , Saberi Fereshte Adib 
Published: February 2021

AbstractBotulinum toxin (BT) therapy is a complex and highly individualised therapy defined by treatment algorithms and injection schemes describing its target muscles and their dosing. Various consensus guidelines have tried to standardise and to improve BT therapy. We wanted to update and improve consensus guidelines by: (1) Acknowledging recent advances of treatment algorithms. (2) Basing dosing tables on statistical analyses of real-life treatment data of 1831 BT injections in 36 different target muscles in 420 dystonia patients and 1593 BT injections in 31 different target muscles in 240 spasticity patients. (3) Providing more detailed dosing data including typical doses, dose variabilities, and dosing limits. (4) Including total doses and target muscle selections for typical clinical entities thus adapting dosing to different aetiologies and pathophysiologies. (5) In addition, providing a brief and concise review of the clinical entity treated together with general principles of its BT therapy. For this, we collaborated with IAB—Interdisciplinary Working Group for Movement Disorders which invited an international panel of experts for the support.