bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vulnerability and resilience of the road transport industry in Poland to the COVID-19 pandemic crisis
Authors: Osińska Magdalena , Zalewski Wojciech 
Published: December 2021

AbstractThe research aims to examine the vulnerability and resilience of road transport enterprises in Poland to a crisis caused by the COVID-19 pandemic. In theory, we refer to the Schumpeterian perspective of creative destruction. In the empirical analysis, survey data on 500 transport companies randomly selected from the database were used. We estimated partial proportional odds models to show the factors responsible for the enterprises' vulnerability and resilience to unforeseen shock. The perspective refers to the total sample size and the division into two subgroups: micro and small and medium enterprises. To justify the results, we calculated a set of statistical indicators and tests. These models enable separating enterprises according to the vulnerability level. Transport enterprises occurred significantly vulnerable to the COVID-19 crisis, particularly the demand shock. The only factor that influenced resilience was the decrease in fuel prices, which allowed a cost reduction. The crisis showed that government aid was helpful in the short run, particularly for micro and small enterprises. The medium-sized enterprises were more resilient than micro and small ones. We formulated several recommendations to help transport enterprises to adjust in the medium term.
Booster Bearing Failure Reduction Through a Novel Thermodynamic Analysis
Authors: Venter Philip , van Eldik Martin 
Published: December 2021

AbstractThe gas booster station of a steel works has experienced excessive bearing failures since commissioning over two decades ago. This station was designed with redundancy, allowing for automatic switch-over between two gas booster fans. Bearing failures were observed, on average once every 15.7 days, with instances where both fans experienced simultaneous downtime. Booster failures resulted in regular station downtime, preventing Coke Oven Gas (COG) transport to an end user. This flammable by-product is used as a heat source and all unutilized volumes are flared, resulting in energy wastages. Furthermore, the absence of COG increases Natural Gas (NG) usage, procured at a cost. Traditional root cause analysis techniques failed to identify the cause of these excessive bearing failures. However, multiple in-depth data analysis studies resulted in a thermodynamic investigation, exposing liquid and solid particles within the COG to be responsible for the failures. This allowed for the design of an in-line particle collector, eliminating excessive failures. Following the particle collector installation, only two strategic bearing changes took place over the next 41 weeks, with reduced bearing vibration levels compared to before. The station experienced no failure downtime during this period, resulting in reduced COG flaring and thus improved energy utilization.
Clinical judgment of the need for professional mental health care in patients with cancer: a qualitative study among oncologists and nurses
Authors: Karchoud Jeanet F. , de Kruif Anja J. Th. C. M. , Lamers Femke , van Linde Myra E. , van Dodewaard-de Jong Joyce M. , Braamse Annemarie M. J. , Sprangers Mirjam A. G. , Beekman Aartjan T. F. , Verheul Henk M. W. , Dekker Joost 
Published: December 2021

Abstract
Purpose
In daily practice, oncologists and nurses frequently need to decide whether or not to refer a patient for professional mental health care. We explored the indicators oncologists and nurses use to judge the need for professional mental health care in patients with cancer.

Methods
In a qualitative study, oncologists (n = 8) and nurses (n = 6) were each asked to select patients who were or were not referred for professional mental health care (total n = 75). During a semi-structured interview, they reflected on their decision concerning the possible referral of the patient. Thematic analysis was used to analyze the data.

Results
Respondents reported using a strategy when judging whether professional mental health care was needed. They allowed patients time to adjust, while monitoring patients’ psychological well-being, especially if patients exhibited specific risk factors. Risk and protective factors for emotional problems included personal, social, and disease- and treatment-related factors. Respondents considered referral for professional mental health care when they noted specific indicators of emotional problems. These indicators included lingering or increasing emotions, a disproportionate intensity of emotions, and emotions with a negative impact on a patient’s daily life or treatment.

Conclusions
This study identified the strategy, risk and protective factors, and the indicators of emotional problems used by oncologists and nurses when judging the need for professional mental health care in patients with cancer.

Implications for Cancer Survivors
Oncologists and nurses can play an important role in the identification of patients in need of professional mental health care.
Increased risk of Graves´ophthalmopathy in patients with increasing TRAb after radioiodine treatment and the impact of CTLA4 on TRAb titres
Authors: Shahida Bushra , Tsoumani Kleoniki , Planck Tereza , Modhukur Vijayachitra , Asp Pernilla , Sundlöv Anna , Tennvall Jan , Åsman Peter , Lindgren Ola , Lantz Mikael 
Published: December 2021

Abstract
Introduction
Treatment of Graves´ disease (GD) with radioiodine increases the risk of developing Graves´ ophthalmopathy (GO), and the link between thyroid and orbital tissue may be the presence of TSH-receptors. Radioiodine increases the titers of TRAb and the aim was to investigate the relationship between GO and TRAb titers after treatment with radioiodine and to define the impact of risk genes.

Methods
GD patients without ophthalmopathy or previous treatment with radioiodine were prospectively included at treatment with radioiodine for hyperthyroidism. A follow-up was performed 1 year later for the registration of GO development. The study was performed at a University Hospital Clinic; a referral center of all patients treated with radioiodine in the south of Sweden. The main outcome measures were the development of TRAb, anti-TPO, and anti-TG after 3 months and GO after 12 months and relationship to the genetic background (HLA, CTLA-4, and CYR61).

Results
Three months of radioiodine TRAb titers increased in two thirds of patients (p < 0.0005) but not in the other third. Anti-TPO titers were associated with TRAb (R = 0.362, p < 0.0001) but not anti-TG. At follow-up 1 year later (n = 204) 32 patients developed GO with a proportion of 70% in the group increasing in TRAb titers and 30% in the group with unchanged or lower TRAb titers (p-value < 0.0005). Patients with GO had higher titers of TRAb than patients without GO. CTLA-4 (rs231775 SNP) was significantly (p < 0.005) associated with TRAb titers above the median three months after radioiodine.

Conclusions
The increase in TRAb titers after treatment with radioiodine is associated with GO and a genetic variation in CTLA-4 is associated with higher titers of TRAb.
Transient Hypoperfusion to Ischemic/Anoxic Spreading Depolarization is Related to Autoregulatory Failure in the Rat Cerebral Cortex
Authors: Menyhárt Ákos , Varga Dániel Péter , M. Tóth Orsolya , Makra Péter , Bari Ferenc , Farkas Eszter 
Published: December 2021

AbstractBackgroundIn ischemic stroke, cerebral autoregulation and neurovascular coupling may become impaired. The cerebral blood flow (CBF) response to spreading depolarization (SD) is governed by neurovascular coupling. SDs recur in the ischemic penumbra and reduce neuronal viability by the insufficiency of the CBF response. Autoregulatory failure and SD may coexist in acute brain injury. Here, we set out to explore the interplay between the impairment of cerebrovascular autoregulation, SD occurrence, and the evolution of the SD-coupled CBF response.MethodsIncomplete global forebrain ischemia was created by bilateral common carotid artery occlusion in isoflurane-anesthetized rats, which induced ischemic SD (iSD). A subsequent SD was initiated 20–40 min later by transient anoxia SD (aSD), achieved by the withdrawal of oxygen from the anesthetic gas mixture for 4–5 min. SD occurrence was confirmed by the recording of direct current potential together with extracellular K+concentration by intracortical microelectrodes. Changes in local CBF were acquired with laser Doppler flowmetry. Mean arterial blood pressure (MABP) was continuously measured via a catheter inserted into the left femoral artery. CBF and MABP were used to calculate an index of cerebrovascular autoregulation (rCBFx). In a representative imaging experiment, variation in transmembrane potential was visualized with a voltage-sensitive dye in the exposed parietal cortex, and CBF maps were generated with laser speckle contrast analysis.ResultsIschemia induction and anoxia onset gave rise to iSD and aSD, respectively, albeit aSD occurred at a longer latency, and was superimposed on a gradual elevation of K+concentration. iSD and aSD were accompanied by a transient drop of CBF (down to 11.9 ± 2.9 and 7.4 ± 3.6%, iSD and aSD), but distinctive features set the hypoperfusion transients apart. During iSD, rCBFx indicated intact autoregulation (rCBFx < 0.3). In contrast, aSD was superimposed on autoregulatory failure (rCBFx > 0.3) because CBF followed the decreasing MABP. CBF dropped 15–20 s after iSD, but the onset of hypoperfusion preceded aSD by almost 3 min. Taken together, the CBF response to iSD displayed typical features of spreading ischemia, whereas the transient CBF reduction with aSD appeared to be a passive decrease of CBF following the anoxia-related hypotension, leading to aSD.ConclusionsWe propose that the dysfunction of cerebrovascular autoregulation that occurs simultaneously with hypotension transients poses a substantial risk of SD occurrence and is not a consequence of SD. Under such circumstances, the evolving SD is not accompanied by any recognizable CBF response, which indicates a severely damaged neurovascular coupling.
Impact of demand response on occupants’ thermal comfort in a leisure center
Authors: Le Cam Andreea , Southernwood Joanna , Ring Daniel , Clarke Dan , Creedon Rosie 
Published: December 2021

AbstractMany assets that are normally installed during an energy-efficient building retrofit can also be used to provide flexible services to the electricity grid. By turning off or turning down some mechanical systems during peak times, it is possible for a building to reduce its load on the electricity network. A field demand response event was simulated at a leisure center in Ireland to evaluate the suitability of the site to participate in the Irish demand response market, to assess how much flexibility it can provide, how much the indoor conditions changed during the test, and to examine whether these remained within satisfactory limits. A survey was conducted to determine whether the occupants perceived any changes to their thermal comfort. The simulation was achieved by identifying non-critical mechanical equipment and turning them off for 2 h. A processing station for demand response and energy monitoring delivered the demand response signal to the site’s building management system. The results show that this site had a flexibility potential of 45 kW, which is considered too low to participate in the demand response market, as Irish aggregators favor sites that can offer over 250-kW flexibility. However, the indoor thermal conditions remained within reasonable ranges and the occupants did not notice the impact of the demand response event. This shows that theoretically, if smaller sites were allowed to sell their flexibility to the electricity market, such leisure centers could participate in demand response services without impacting occupants’ comfort.
Gaze and speech behavior in parent–child interactions: The role of conflict and cooperation
Authors: Holleman Gijs A. , Hooge Ignace T. C. , Huijding Jorg , Deković Maja , Kemner Chantal , Hessels Roy S. 
Published: December 2021

AbstractA primary mode of human social behavior is face-to-face interaction. In this study, we investigated the characteristics of gaze and its relation to speech behavior during video-mediated face-to-face interactions between parents and their preadolescent children. 81 parent–child dyads engaged in conversations about cooperative and conflictive family topics. We used a dual-eye tracking setup that is capable of concurrently recording eye movements, frontal video, and audio from two conversational partners. Our results show that children spoke more in the cooperation-scenario whereas parents spoke more in the conflict-scenario. Parents gazed slightly more at the eyes of their children in the conflict-scenario compared to the cooperation-scenario. Both parents and children looked more at the other's mouth region while listening compared to while speaking. Results are discussed in terms of the role that parents and children take during cooperative and conflictive interactions and how gaze behavior may support and coordinate such interactions.
Small Farmers Large Field (SFLF): a synchronized collective action model for improving the livelihood of small farmers in India
Authors: Baruah Sampriti , Mohanty Samarendu , Rola Agnes C. 
Published: December 2021

AbstractThis study pilots the collective action model “Small Farmers Large Field (SFLF)” to overcome the disadvantages faced by millions of small and marginal farmers due to diseconomies of scale and lack of bargaining power in the supply chain. This model is participatory and flexible and allows small farmers to benefit from achieving economies of scale by organizing themselves into groups and synchronizing and harmonizing selected operations. It was piloted in two villages of Odisha, an eastern Indian state, with 112 farmers (35 females and 77 males). These farmers organized themselves into groups and synchronized their operations such as nursery bed management, transplanting, and harvesting collectively to achieve economies of scale. The SFLF farmers purchased inputs (seed and fertilizer) and sold paddy as a group to increase their bargaining power in price negotiations. The results from this pilot study showed that the participating farmers almost doubled their profits. Apart from the monetary benefits, these farmers saved time in many joint activities, including input (seed and fertilizer) purchase, paddy sale, and nursery bed management. Other important benefits of the harmonization and synchronization of farming operations were social harmony and sustainability of the farming system.
Assessing and enhancing the impact potential of marketing articles
Authors: Jaakkola Elina , Vargo Stephen L. 
Published: December 2021

AbstractAlthough the impact of marketing is a recognized priority, current academic practices do not fully support this goal. A research manuscript’s likely influence is difficult to evaluate prior to publication, and audiences differ in their understandings of what “impact” means. This article develops a set of criteria for assessing and enhancing a publication’s impact potential. An article is argued to have greater influence if it changes many stakeholders’ understandings or behaviors on a relevant matter; and makes its message accessible by offering simple and clear findings and translating them into actionable implications. These drivers are operationalized as a checklist of criteria for authors, reviewers, and research supervisors who wish to evaluate and enhance a manuscript’s potential impact. This article invites scholars to further develop and promote these criteria and to participate in establishing impact evaluation as an institutionalized practice within marketing academia.
Spatial distribution of ground water quality index using remote sensing and GIS techniques
Authors: Dandge K. P. , Patil S. S. 
Published: December 2021

AbstractWater is a vital and widely spread component required for sustaining the life. Groundwater is vastly valuable source and it is extremely beneficial for the human beings. But, the toxic elements release from sources such as industries, landfills as well as non-point causes of pollution such as pesticides and fertilizer from the past year showed high levels of pollution in ground water, hence this is very crucial for evaluating the water quality not only for it’s existing usage, but also a its capacity to develop as a sustainable source of water for human utilization. In rural areas of India, Groundwater is a significant water-drinking source. In Bhokardan area of Jalna District, quality of ground water is great significance, because it is a key alternative source of domestic supply along with drinking water and peoples residing there facing several water quality issues for drinking purpose. In this current research work, an endeavor has been developed to investigate the quality of groundwater as well as spatial distribution by utilizing Remote Sensing along with GIS approaches. Water quality analysis was performed for developing the quality index of water, by utilizing 12 quality parameters of water like Alkalinity, pH, Electrical Conductivity, Fluoride, Chloride, Nitrate, Sulphate, Potassium, Total Hardness, E. coli, Turbidity and Total Dissolved Solids measured at 35 different selected locations in this research work. Spatial distribution map showed that each region of research area falls under category of “Poor water” and “Very poor water” except some sites at Northern regions of the area which falls under “Good water” category during pre-monsoon, whereas most of the sites from Northern and Southern part of the region shifted category from poor to good water along with very poor to poor water during post-monsoon season. The quality index data of water of the current research disclosed that, the high WQI “Water Quality Index” values in the samples of groundwater were principally due to the occurrence of higher values of turbidity and E. Coli. The higher level of water quality parameters like TH, EC, alkalinity, potassium, TDS, chloride and fluoride were also accountable for high values of WQI in this research work. None of the location falls under excellent quality for water during pre-monsoon as well as post-monsoon season.
Injuries in Elite Men’s Rugby Union: An Updated (2012–2020) Meta-Analysis of 11,620 Match and Training Injuries
Authors: Williams Sean , Robertson Charli , Starling Lindsay , McKay Carly , West Stephen , Brown James , Stokes Keith 
Published: December 2021

Abstract
Background
The most recent meta-analytic review of injuries in elite senior men’s Rugby Union was published in 2013. The demands of the game at the elite level are continually changing alongside law amendments and developments in player preparation. As such, an updated meta-analysis of injury data in this setting is necessary.

Objective
To meta-analyse time-loss injury data in elite senior men’s Rugby Union between 2012 and 2020.

Methods
Electronic databases were searched using the keywords ‘rugby’ and ‘inj*’. Nineteen studies met the inclusion criteria. Injury incidence rate data were modelled using a mixed-effects Poisson regression model. Days missed data were modelled using a general linear mixed model.

Results
The included data encompassed a total of 8819 match injuries and 2801 training injuries. The overall incidence rate of injuries in matches was 91 per 1000 h (95% confidence interval (CI) 77–106). The estimated mean days missed per match injury was 27 days (95% CI 23–32). The overall incidence rate of match concussions was 12 per 1000 h (95% CI 9–15). The overall incidence rate of training injuries was 2.8 per 1000 h (95% CI 1.9–4.0). Playing level was not a significant effect modifier for any outcome.

Conclusions
The injury incidence rate and mean days missed per injury in the present meta-analysis were higher, but statistically equivalent to, the 2013 meta-analysis (81 per 1000 h and 20 days, respectively). The injury incidence rate for match injuries in elite senior men’s Rugby Union is high in comparison to most team sports, though the training injury incidence rate compares favourably. The tackle event and concussion injuries should continue to be the focus of future preventative efforts.
“Havens of mercy”: health, medical research, and the governance of the movement of dogs in twentieth-century America
Authors: Kirk Robert G. W. , Ramsden Edmund 
Published: December 2021

AbstractThis article argues that the movement of dogs from pounds to medical laboratories played a critically important role in debates over the use of animals in science and medicine in the United States in the twentieth century, not least by drawing the scientific community into every greater engagement with bureaucratic political governance. If we are to understand the unique characteristics of the American federal legislation that emerges in the 1960s, we need to understand the long and protracted debate over the use of pound animals at the local municipal and state level between antivivisectionists, humane activists, and scientific and medical researchers. We argue that the Laboratory Animal Care Act of 1966 reflects the slow evolution of a strategy that proved most successful in local conflicts, and which would characterize a “new humanitarianism”: not the regulation of experimental practices but of the care and transportation of the animals being provided to the laboratory. Our analysis is consistent with, and draws upon, scholarship which has established the productive power of public agencies and civil society on the periphery of the American state.
Biomass Microcapsules with Stem Cell Encapsulation for Bone Repair
Authors: Yang Lei , Liu Yuxiao , Sun Lingyu , Zhao Cheng , Chen Guopu , Zhao Yuanjin 
Published: December 2021

Abstract
Bone defects caused by trauma, tumor, or osteoarthritis remain challenging due to the lack of effective treatments in clinic. Stem cell transplantation has emerged as an alternative approach for bone repair and attracted widespread attention owing to its excellent biological activities and therapy effect. The attempts to develop this therapeutic approach focus on the generation of effective cell delivery vehicles, since the shortcomings of direct injection of stem cells into target tissues. Here, we developed a novel core-shell microcapsule with a stem cell-laden core and a biomass shell by using all-aqueous phase microfluidic electrospray technology. The designed core-shell microcapsules showed a high cell viability during the culture procedure. In addition, the animal experiments exhibited that stem cell-laden core-shell microcapsules have good biocompatibility and therapeutic effect for bone defects. This study indicated that the core-shell biomass microcapsules generated by microfluidic electrospray have promising potential in tissue engineering and regenerative medicine.
The flight efficiency analysis on the Multi-Arrival Route Point Merge System
Authors: Oren A. , Sahin O. 
Published: December 2021

AbstractThis study proposes a new operational concept of the Point Merge System, called Multi-Arrival Route Point Merge System (MAR-PMS), which is an air traffic control method used to sequence aircraft arrivals in a given terminal control area. The proposed concept enables the additional arrival routes that have an angular difference to each sequencing leg. Furthermore, a time-indexed 0-1 linear programming model is formulated. The obtained results are validated in a real time simulation. The comparison results of PMS and MAR-PMS show that the average reduction of 19% of total flight time, 23% of total flight distance, and 19% in total fuel burned and reduction in CO2 emissions in favor of a proposed concept.