bluuebunny/crossref_metadata_2025_split huggingface dataset:
In silico screening of natural products targeting chorismate synthase
Authors: Zaghlool Al-Khayyat Mohammed 
Published: September 2021

Introduction: Chorismate synthase catalyzes the final step in shikimate acid pathway involved in synthesis of aromatic compounds in bacteria.This enzyme can be a possible molecular target for design of antibiotics. Materials and Methods: Homology modeling and molecular dockingwere performed to screen about one hundred natural compounds in order to find inhibitors of enzymes as a possible new target. A model wasbuilt by SWISS-MODEL and its quality was assessed by ERRAT, ProSA, Rampage and MolProbity servers. Docking experiments were performedand pharmacokinetics and toxicities were studied by admetSAR. Results: The predicted model was reliable to be used in docking experiments.Amentoflavone had the highest binding affinity of -10.0 Kcal/mol. Probabilities indicated that rotenone may inhibit P-glycoprotein I, hinokiflavone and silybin may inhibit P-glycoprotein II, while taspine acts on both types of P-glycoproteins. Amentofalavone, hinokiflavone, rotenone and silybin have a probability of inhibiting cytochromes that are involved in oxidation stage of metabolism. Conclusions: These compounds had binding affinities towards FMN binding site of the enzyme model and may be considered in the research for new antibacterial agents but only when their drug interactions are fully investigated.
CAVAKHETİ BÖLGESİ ÖRNEĞİNDE GÜRCÜ VE ERMENİ DİL İLİŞKİLERİNE GÖRE SİVİL ENTEGRASYON SORUNLARININ ÇEŞİTLİ YÖNLERİ ÜZERİNE
Authors: KHACHATURİANİ Jana 
Published: September 2021

Gürcistan’da Gürcülerin yanı sıra bu ülkede ihtiyaçları ve kültürel özlemleri ile bir yaşam biçimi oluşturan diğer milletlerde de yaşamaktadır. Ancak çoğu durumda, mezhepsel, etnokültürel ve dilsel farklılıklar nedeniyle belirli marjinalleşme belirtileri de gözlemlenmiştir. Bu nedenle, nüfusun birliğini sağlamak için devletin vatandaşlarının yakınlaşmasını engelleyen tüm faktörlerin üstesinden gelmesi gerekmektedir. Bunlardan en önemli sayılan biri de dil yeterliliği sorunudur. Devlet diline hâkim olmak ise başarı için vazgeçilmez bir koşul olarak kabul edilmiştir. Bildiğiniz gibi bir ülkenin egemenliği büyük ölçüde devletin diline bağlıdır; devlet dilinin korunması ve yaygınlaştırılması devletin istikrarının garantisidir. Ülkedeki dil sorunu ise sivil entegrasyon eksikliğini açıkça göstermektedir. Dil, sivil birliğinin garantisidir; en azından insanlar birbirini anlamalı, başka bir deyişle "Aynı dili" konuşmaları gerekir. Günümüzde devletin temel önceliği, ülke nüfusunu tek bir sosyal alanda buluşturmaktır. Bu yol ise devletin resmi diline sahip olmaktan geçer.
Ermenistan, Gürcistan'a komşu olan ülkelerden biridir. Bu nedenle, Ermenilerin tarihsel olarak Gürcistan ve Ermenistan arasında kolayca hareket etmeleri de doğaldır. Ermeniler birçok durumda Gürcistan’a yerleştiler ve iş sahibi de oldular. Geçmişte Ermenilerin göçü genellikle askeri veya afet nedeniyle, bazen ticari ve diğer ekonomik çıkarlardan ve bunun gibi nedenlerden dolayı olmuştur.
Sovyetler Birliği dönemi Ruslaştırma politikası ve Sovyet Cumhuriyetlerin bağımsızlığı üzerindeki kısıtlama koşullarında Gürcüce konuşmayan nüfus yasal olarak sadece Gürcü vatandaşlığına sahipti, ama zihinsel olarak nüfusun tanımsız bir sivil kimliği vardı. Sovyetler Birliği'nin çöküşünden sonra sivil entegrasyon süreci daha karmaşık hale geldi. Oluşan durumun birkaç sebebi vardı:
•	Gürcüce konuşmayan nüfusun Gürcü dilini öğrenmek için düşük motivasyonu ve
devlet iradesinin zayıflığı;
•	Gürcistan'ın Gürcüce konuşmayan nüfus için Gürcü dilinin "ikinci dil" olarak vasfetmesi ve böylece anılan nüfusun motivasyonunu düşürmesi;
•	Gürcüce konuşmayan nüfus için Gürcü dili ders kitaplarının ve öğretmenlerin düşük nitelikleri;
•	Gürcüce konuşmayan nüfus için Gürcü dilini öğretme metodolojisinin kusurlu oluşu.
Theology and the Knowledge of Persons
Authors: Stump Eleonore 
Published: September 2021

The aim of the paper is to discern between philosophy and theology. A philosopher is looking after impersonal wisdom, a theologian searches for a personal God. This differentiation is fundamental because knowledge of persons differs from knowledge that. The author shows how taking into account the fact that theology is based on the second-person knowledge changes the way one should approach the hiddenness argument.
* The paper was originally published in: Fiona Ellis (ed.), New Models of Religious Understanding (Oxford: OUP, 2017), 172–90. Reprinted by the permission of the Author.
PROJETOS SOCIETÁRIOS EM TEMPOS DE PANDEMIA E O EXERCÍCIO PROFISSIONAL DE ASSISTENTES SOCIAIS DO PARÁ
Authors: Braga Cilene Sebastiana da Conceição , Jorge Ediane Moura , Gama Lais Ribeiro , Gomes Mickaely de Lima 
Published: September 2021

Este artigo expõe os resultados parciais da pesquisa intitulada “Projetos Societários em disputa em tempos de pandemia e o exercício profissional do Assistente Social do Pará/Amazônia legal” vinculada a um Grupo de Estudos da UFPA. Apresenta o levantamento da literatura pertinente ao tema produzida por Assistentes Sociais e publicada em periódicos. Apresenta dados acerca do número de infectados na região Amazônica, especificamente no Estado do Pará. Analisa os dados a partir de uma perspectiva teórica-crítica. Realizamos pesquisa bibliográfica e pesquisa documental. O artigo exibe breves reflexões sobre a realidade socioeconômica na pandemia na Região Amazônica e no Estado do Pará,e principais problematizações em termos de ausência de direitos sociais e desafios para o (a) Assistente Social. Os resultados mostram que os (as) assistentes sociais enfrentam o medo, a insegurança e o deterioramento das condições de trabalho no enfrentamento da pandemia.SOCIAL PROJECTS IN PANDEMIC TIMES AND THE PROFESSIONAL EXERCISE OF SOCIAL WORKERS IN PARÁAbstractThis article exposes the partial results of the research entitled "Corporate Projects in dispute in times of pandemic and the professional practice of the Social Worker of Pará / Legal Amazon" linked to a UFPA Study Group. It presents a survey of the pertinent literature produced by Social Workers and published in periodicals. It presents data about the number of infected in the Amazon region, specifically in the State of Pará. The data are analyzed from a theoretical-critical perspective. We carry out bibliographic and documentary research. The article shows brief reflections on the socioeconomic reality in the pandemic in the Amazon Region and in the State of Pará, and main problems in terms of the absence of social rights and challenges for the Social Worker. The results show that social workers face fear, insecurity and deteriorating working conditions in the face of the pandemic.Keywords: Pandemic. Professional Practice. Neoliberalism, Precariousness. Amazon
THE RELATIONSHIP OF SOCIAL SUPPORT WITH THE DEGREE OF NAUSEA AND VOMITING IN PREGNANCY
Authors: Junandar Cempaka Yudithia , Wittiarika Ivon Diah , Utomo Budi , Ernawati Ernawati 
Published: September 2021

Abstract Background : At the beginning of a pregnancy the mother experiences various processes of transition or adaptation regarding changes in herself, so that she really needs support from her environment. Lack of social support can worsen the physiological complaints of pregnant women including Nausea and Vomiting in Pregnancy (NVP). Complaints of nausea and vomiting can affect the mother in carrying out daily activities, affect the mother's social situation with the environment and cause stress. Therefore, it is important to research the relationship between social support and the degree of nausea and vomiting in first and second-trimester pregnant women. Method : This research method is observational analytic with cross sectional research design. Sampling used the total sampling method with the criteria of pregnant women who had complaints of nausea and vomiting. Collecting data using primary data using a 24-hour PUQE questionnaire that measures the duration and frequency of nausea and vomiting and the MSPSS questionnaire measuring social support. The data collected were analyzed using the Spearman test (p<0.15). Results : Out of 47 respondents, 34 pregnant women (72.3%) received high social support. Besides that, 24 out of 47 respondents (51.1%) experienced moderate degree of NVP. In this study, there were no respondents who experienced severe degree of NVP. Spearman test analysis results obtained p= 0.833 or p>0.15. Conclusion : There is no relationship between social support with NVP in first and second trimester of pregnancy.
EFFECTS OF FAMILY SUPPORT AND MATERNAL PSYCHOLOGICAL ON EXCLUSIVE BREASTFEEDING
Authors: Eka Firnanda MCRP Jenica Hillary , Etika Risa , Lestari Pudji 
Published: September 2021

AbstractBackground: Breastmilk is the best food that a mother can give to her baby from birth until the first 6 months of life to support growth and development during the first 1000 days of life. The success of exclusive breastfeeding is influenced by several factors. The purpose of this study is to analyze the support of family and mother to support exclusive breastfeeding. Method: This research method is cross sectional with a retrospective study design. The number of samples was 48. The independent variables were family and psychological assistance from the mother. The successful variable is exclusive breastfeeding. The research instrument used was a questionnaire. Data analysis using Fisher Exact statistical tests. Results: The results showed that there is no influence between family support and psychological of mother on the success of exclusive breastfeeding. Fisher Exact trial results related to family support for exclusive breastfeeding showed p = 0.339 (p> 0.05), psychological motivation of mothers towards exclusive breastfeeding showed p = 0.167 (p> 0.05). Conclusion: This data shows inappropriate between family support and psychological mother to exclusive breastfeeding.
Heterotopic Ossification in the Posterior Septum of the Knee Excised by an Arthroscopic Dual Portal Technique
Authors: Kambhampati Srinivas B.S. , Vasudeva Nagashree , Yalamanchili Poornachandra Rao 
Published: September 2021

Case:
We present a 15-year-old adolescent girl with acute onset knee pain and a lesion in the posterior septum (PS) believed to be an infectious process on initial investigations. This was excised successfully using a combination of transseptal and transnotch portals and proven to be a case of heterotopic ossification (HO) within the PS with an excellent outcome within 4 weeks. Our case is unique for the pathology that occurred and the technique of excision.

Conclusion:
HO in the PS is a rare pathology that can be treated arthroscopically using a combination of portals. Removal causes complete resolution of symptoms.
Understanding ESP Performance Under High Viscous Applications and Emulsion Production
Authors: Pastre Luiz , Biazussi Jorge , Monte Verde William , Bannwart Antonio 
Published: September 2021

Abstract
Although being widely used as an artificial lift method for heavy oil field developments, Electrical Submersible Pump (ESP) performance in high viscous applications is not fully understood. In order to improve knowledge of pump behavior under such conditions, Equinor has developed stage qualification tests as part of the technical requirements for deploying ESPs in Peregrino Field located offshore Brazil and has funded a series of research efforts to better design and operate the system more efficiently.
Qualification tests were made mandatory for every stage type prior to field deployment in Peregrino. It is known that the affinity laws don´t hold true for high viscosity applications. Therefore, extensive qualification tests are required to provide actual stage performance in high viscous applications. Test results are used to optimize ESP system design for each well selecting the most efficient stage type considering specific well application challenges. In addition, the actual pump performance improves accuracy in production allocation algorithms. A better understanding of ESP behavior in viscous fluid application helps improving oil production and allows ESP operation with higher efficiency, increasing system run life.
Shear forces inside ESP stages generate emulsion that compromises ESP performance. Lab tests in controlled environments have helped Equinor to gather valuable information about emulsion formation and evaluate ESP performance in conditions similar to field application. Equinor has funded studies to better understand two-phase flow (oil-water) which allowed visualization and investigation of oil drops dynamics inside the impeller. In addition, experimental procedures were proposed to investigate the effective viscosity of emulsion at pump discharge and the phase inversion hysteresis in the transition water-oil and oil-water emulsion.
In addition to qualification tests and research performed to better understand system behavior, Equinor has developed and improved procedures to operate ESP systems in high viscous applications with emulsion production during 10 years of operation in Peregrino field. Such conditions also impose challenges to ESP system reliability. Over the years, Equinor has peformed failure analysis to enhance ESP system robustness which, combined with upper completion design, have improved system operation and reliability decreasing operating costs in Peregrino field.
Water Blooms—A Potential Threat to Male Reproduction: Clues from Fishes and Rodent
Authors: Zhang Xu , Chen Xinglin , Zhang Tongtong , Ren Xiaohan , Zhou Xiang , Li Guangyao , Gong Zixuan , Su Shifeng , Wang ShangQian , Qin Chao 
Published: September 2021

Abstract
Toxic cyanobacteria blooms are a potential threat to global aquatic ecosystems and human health. Microcystin-leucine-arginine (MC-LR) is the most toxic variant of microcystins (MCs), and exposure to MCs can damage the male reproductive system.Two electronic databases were searched for controlled studies of rodents and fishes published before September 2020. Effect sizes were calculated for eight main reproductive parameters, including sperm count, sperm motility, sperm morphology, serum testosterone, testis weight, serum follicle stimulating hormone (FSH), serum luteinising hormone (LH) and serum estradiol. Nine meta-analyses of individual parameters were conducted using R version 4.0.2. Fifteen studies were included in the meta-analysis. In the studies of rodents, exposure to MC-LR by intraperitoneal injection or intragastric administration yielded statistically significant effects on sperm count (standardised mean difference (SMD) = -1.7426 (95% CI: -2.2098 to -1.2754)), abnormal sperm rate (SMD = 1.6714 (95% CI: 0.9702 to 2.3726)), sperm motility (SMD = -2.8822 (95% CI: -3.9811 to -1.7834)), testis weight (SMD = -2.8822 (95% CI: -3.9811 to -1.7834)) and serum FSH (SMD = 0.4707 (95% CI: 0.0659 to 0.8756)). In fish studies, the changes in serum testosterone (SMD = 0.5521 (95% CI: 0.1652; 0.9391)) and estradiol (SMD = 0.6398 (95% CI: 0.1896 to 1.0900)) concentrations are considered to be statistically significant. Dose–response analysis reflected the dynamic changes of male reproductive function caused by MC. Short-term exposure to MC-LR can affect the function of the male reproductive system in rodents and fish. Elevated dosage or extended exposure time may worsen the damage. Human-related research on MC-LR exposure is very necessary to protect health and the water environment.
Selection of Feasible Leaching Method for Recovery of Heavy Metals from E-waste using Analytic Hierarchy Approach
Authors: Minocha Garima , khandegar vinita , Acharya Sanigdha 
Published: September 2021

Abstract
Amount of e-waste is increasing tremendously over the years, from almost getting doubled each year. 40 % e-waste consists of many metals and precious metals. The rapid growth in technology development is alarming, as a result more and more e-waste is generating. This leads to myriad problems for handling or management of e-waste. Traditional methods of disposal of e-waste such as landfilling, composting and incineration is major threat to the environment and life. In this study recovery of metals through hydro-metallurgical process such as thiosulfate (M1), iodide (M2) aqua-regia (M3) and thiourea (M4) leaching methods were compared in terms of economic feasibility, environmental impact and reagent reuse in order to find out a feasible leaching method using Analytic Hierarchy Process (AHP). The selection of feasible leaching method has been performed by applying the Saaty, ranking. From the final ranking are, thiosulfate (M1) scored = 0.09, iodide (M2) = 0.16, aqua-regia (M3) = 0.39 and thiourea (M4) = 0.39. From the result M3 and M4 are the feasible method for recovery of heavy metals from E-waste.
Prevalence and associated factors of Female genital mutilation among reproductive age women’s of Damot Gale woreda, Wolaita Zone, Southern Ethiopia: a cross-sectional study, 2018
Authors: Anjulo Bargude Balta , Lambebo Amanuel Fanta 
Published: September 2021

Abstract
Background: Female genital mutilation (FGM) is estimated to have been practiced on at least 200 million girls and women in 30 countries around the world. Clitoridoctomy is the most common type of FGM in Ethiopia.Objectives: The aim of the study was to assess the magnitude of Female Genital Mutilation and associated factors among women’s in Damot Gale Woreda of Wolayita zone.Methods: A quantitative community-based cross-sectional study was used. Face-to-face interviews with prepared questionnaires were used to collect data. SPSS version 20 software was used to analyze the data. The prevalence of FGM was determined using descriptive statistics. The researchers utilized a bivariate and multivariate logistic regression model to find independent determinants of FGM.Result: 296 women were circumcised out of a total of 333, indicating that FGM is prevalent in the research area (88.9%). Mother education (AOR: 0.454, 95% CI: 0.209-0.984), age (AOR-1.86, 95% CI: 0.42-0.98)), knowledge that FGM causes health problems (AOR: 0.356, 95% CI: 0.145-0.877), and support for tradition (AOR: 14.595, 95% CI: 3.391-6.807) were all independently linked to FGM.Conclusion: Prevalence of FGM was associated with age, education, Knowledge of health problems and Tradition.
Exploring the Intersectionality of Family SES and Gender with Psychosocial, Behavioural and Environmental Determinants of Physical Activity in Dutch Adolescents: A Cross-Sectional Study
Authors: Braga André Mamede Soares , Erdem Özcan , Noordzij Gera , Merkelbach Inge , Kocken Paul , Denktas Semiha 
Published: September 2021

Abstract
BackgroundExamining the determinants of adolescent’s physical activity (PA) and how they may differ according to the intersection of gender and family socioeconomic status (SES) can support the development of tailored interventions to more effectively promote adolescents’ PA. This study explored how the influence of psychosocial, behavioural and environmental determinants on adolescent’s PA differed according to gender and family SES. MethodsThis study used data from the Dutch survey Health Monitor Youth 2015. Adolescents (n=9,068) aged 12-19 were included for the study. The associations between psychosocial, behavioural, and environmental determinants and PA (days per week engaging in at least one hour of PA) were examined with multilevel linear regression analysis. Potential interactions between these determinants, gender and family SES were explored.ResultsOn average, adolescents engaged in at least one hour of PA for 4,2 days per week. Poor self-perceived health, low peer social support, and a weak connection with the environment were all associated with lower PA in adolescents. Daily smoking, cannabis use, risk of problematic gaming and social media use, as well as lack of daily consumption of fruit, vegetables, water and breakfast were associated with lower PA, whereas binge drinking was not. Interactions revealed that poor self-perceived health was associated with lower PA in adolescents from moderate- and high-SES families, but not in low-SES adolescents, whereas cannabis use was only associated with lower PA amongst low-SES adolescents. Low peer social support was associated with lower PA across all groups, but it was most strongly associated with lower PA amongst male adolescents from low-SES families than in other subgroups. Amongst low-SES males, low peer social support was associated with a 1.47 reduction in days engaging in sufficient PA, compared with a 0.69 reduction for high-SES males.ConclusionsThis study identified several psychosocial, behavioural and environmental determinants that can be targeted to potentially increase adolescent’s PA. We also found that correlates of PA differed according to the intersection of gender and family SES. Our findings suggest that PA interventions should be tailored according to gender and SES to address the specific needs, barriers and facilitators of different subgroups.
Synthetic Datasets for Numeric Uncertainty Quantification
Authors: Kabir Hussain Mohammed Dipu , Abdar Moloud , Khosravi Abbas , Nahavandi Darius , Mohamed Shady , Sriniva Dipti , Nahavandi Saeid , Suganthan Ponnuthurai Nagaratnam 
Published: September 2021

Abstract
In this paper, we propose ten synthetic datasets for point prediction and numeric uncertainty quantification (UQ). These datasets are split into train, validation, and test sets for model benchmarking. Equations and the description of each dataset are provided in detail. We also present representative shallow neural network (NN) training and Random Vector Functional Link (RVFL) training examples. Both training train models for the point prediction. We perform uncertainty quantification with the consideration of a gaussian and homoscedastic distribution. As the distribution consideration and models are rudimental, much room exists for further explorations and improvements. The dataset and scripts are available at the following link: https://github.com/dipuk0506/UQ-Data