bluuebunny/crossref_metadata_2025_split huggingface dataset:
An optimization approach for green tourist trip design
Authors: Divsalar Ghazaleh , Divsalar Ali , Jabbarzadeh Armin , Sahebi Hadi 
Published: June 2021

Abstract
In this paper, the Multi-Objective Multi-Modal Green Tourist Trip Design Problem (MO-MM-GTTDP) as the multi-modal variant of the orienteering problem is investigated. For this problem, a Multi-Objective mixed-integer linear model is formulated, which maximizes the total score of the Trip, minimizes the total cost of the trip as well as the total emission produced in the trip. Various transportation modes are considered for the tourist to choose to move between points of interest (POIs). The tourist choice may be affected by the transportation time and cost. Moreover, choosing the transportation mode will have an impact on the amount of trip pollutants. The cost of visiting POIs, as well as the cost of transportation between POIs, is considered as the total cost of the tour. In addition, a Multi-Objective Variable Neighborhood Search (MOVNS) algorithm is designed to solve instances of this problem. Moreover, a, E - constraint method is implemented in CPLEX and used to evaluate the performance of the presented MOVNS. New instances of the problem are generated based on the existed benchmark OP instances. The conclusion is the high quality of the proposed MOVNS algorithm solutions in practically acceptable computation time (few seconds). Finally, a small case study based on real data on several POIs in the city of Tehran is generated and used to demonstrate the performance of the proposed model and algorithm in practice. For this case study, by using the multi-attribute decision-making method of TOPSIS, the obtained non-dominated solutions are ranked, and the best ones are presented to the tourist.
Exergy and Energy Analysis of a Tubular Solar Still with and without Fins: Comparative Theoretical and Experimental Approach
Authors: Sathyamurthy Prof. Dr. Ravishankar , Kabeel Abd Elnaby , Chamkha Ali , Kumar Hemanth Arun , Venkateswaran Hariprasath , Manokar Athikesavan Muthu , Bharathwaaj Ramani , Vasanthaseelan Sathiyaseelan 
Published: June 2021

Abstract
Today, availability of clean water is hard as the residents are expanding and moving fast to achieve rapid urbanization as a result need for clean water has been raised. Solar stills are the solution to desalinate to obtain pure water. This paper represents the theoretical and experimental study of tubular solar still with and without fins. The reading was recorded from 8:00 AM to 6:00 PM. Efficiency of TSS with fins and without fins are 23.39% and 13.76% respectively. The rate of irreversibility from the basin of TSS with flat is higher than TSS with finned absorber. Similarly, the rate of irreversibility from water is significantly reduced using finned absorber. Also, the exergy efficiency of TSS with finned absorber is higher compared to TSS with flat absorber.
Deformation and Instability Properties of Cemented Gangue Backfill Column under Step-By-Step Load in Constructional Backfill Mining
Authors: Guo Yuxia , Ran Hongyu , Feng Guorui , Du Xianjie , Zhao Yonghui , Xie Wenshuo 
Published: June 2021

Abstract
Constructional backfill mining with cemented gangue backfill column can solve the environmental issues caused by mining activities and the accumulation of waste gangue at a low cost. To study the deformation and instability properties of cemented gangue backfill columns during the advancement of coal mining face, five step-by-step loading paths were adapted to mimic the different loading processes of the roof. The lateral deformation at different heights and axial deformation of the sample were monitored. The results show that the deformation and instability of the backfill column have the properties of loading paths and are affected by the step-by-step loading path. When stress-strength ratio (SSR) is less than 0.6, the lateral of backfill column shrinks during the creeping process. In high-stress levels, lateral creep strain develops faster than axial creep strain. The backfill column has characteristics of axial creep hardening and lateral creep softening during the step-by-step loading process. The instantaneous deformation modulus and instantaneous Poisson’s ratio show an upward trend. The bearing capacity of backfill column under the step-by-step load is related to loading paths and is no less than uniaxial compressive strength. The non-uniformity of the lateral deformation of backfill column leads to excessive localized deformation that mainly occurs in the middle, causing the overall instability. The development of cracks of backfill column under step-by-step load could be divided into 4 stages according to SSR. Under different step-by-step loading paths, the axial creep strain rate is nearly a constant before entering the accelerated creep stage. A nonlinear creep constitutive model with a creep strain rate trigger was proposed to depict the development of axial strain under step-by-step load. This research will provide a scientific reference for the design of the advancing distance and cycle for the hydraulic support, and reinforcement of the backfill column.
DNA Barcoding of Two Narrow Endemic Plants; Astragalus Argaeus and Astragalus Stenosemioides from Mount Erciyes, Turkey
Authors: Selamoğlu handan Şapcı 
Published: June 2021

Abstract
The genetic resources and biological diversity of countries are very important. Biodiversity and genetic resources should be protected, especially as endemic species. In this concept, DNA barcoding studies are an effective way to identify an unknown taxon and protected the biodiversity of a country. Astragalus argaeus and A. stenosemioides are narrow endemic species from Mt. Erciyes, Turkey. To determine its phylogenetic relationships and DNA barcoding, sequence data from the chloroplast DNA (matK region) were analyzed by parsimony, maximum likelihood, and Bayesian methods. In this study, A. argaeus, A. stenosemioides samples, and 23 sequences from GenBank, including a closely related species were performed. The phylogenetic analysis showed that the matK gene region could clearly distinguish A. argaeus and A. stenosemioides from its closely related species. DNA barcoding surveys can contribute to taxonomic and biodiversity research, various molecular ecology, and population genetics studies. Also, it is possible to determine the species by separating the matK DNA gene region, which is one of the molecular characters, and A. argaeus and A. stenosemioides have been successfully barcoded for the first time; therefore, it has been shown that this gene region can be used for barcoding.
Effects Of Educational Intervention Based On Integrated Social Marketing Approach On Regular Physical Activity of Female Students: A Study Protocol For A Cluster Randomised Trial
Authors: Moeini Babak , Rezapur-Shahkolai Forouzan , Heidarimoghadam Rashid , Tapak Leili , Geravandi Azam 
Published: June 2021

Abstract
Background: A sedentary lifestyle is recognized as a risk factor for chronic diseases. The aim of this study was to identify the factors related to regular physical activity in adolescents. Also design effective social marketing interventions on these factors in primary schools in Kermanshah (western Iran).Method: This study will be a parallel randomised controlled trial (RCT) conducted at a secondary school in Kermanshah. This protocol conforms to the Consolidated Standard of Reporting Trials (CONSORT) Statement and is registered at the Iranian Registry of Clinical Trials (IRCT:IRCT20200621047858N1). This research will be conducted in three phases that correspond to the first to seventh stages of the social marketing operational model, i.e. the SMART model. Given that this study is a three-stage study, an interventional study will be conducted to investigate the effect of educational intervention on regular physical activity behavior among female junior high school students. In this study, we will have an intervention group and a control group. In each area (north and south of the city), using the division by the school education department, is divided into three categories (rich, middle-income and low-income) and a simple random method is selected from each category of one school (3 intervention schools and 3 control schools. The sample size required for the intervention and control group is calculated as 108 people. Individuals are evaluated for regular physical activity according to the stages of behavior change before and after the intervention.Trial registration: IRAN Clinical Trials Register IRCT20200621047858N1 (date of registration: 2020/7/25 randomized controlled trial registered).Ethics approval: IR.UMSHA.REC.1398.952
Managing Gene Expression in Pseudomonas Simiae EGD-AQ6 for Chloroaromatic Compound Degradation
Authors: Ghosh Saheli , Purohit Hemant , Qureshi Asifa 
Published: June 2021

Abstract
Pseudomonas simiae EGD-AQ6 showed utilization of chloroaromatic compound, 2-4-dichlorophenoxyacetic acid (2,4-D) efficiently in its biofilm phenotype. The differential rates of accumulation of intermediate metabolite 4-chlorocatechol (4-CCA) were significant in both planktonic and biofilm phenotypes; also increased number of biofilm cells were observed during 2,4-D utilization. Interestingly, response surface analysis demonstrated the combined positive effects of 2,4-D degradation and 4-CCA accumulations. Also, gene expression profiles showed significant up-regulation of degradative and biofilm genes (particularly pellicle forming genes) in the biofilm phenotypes than their planktonic counterparts, thereby confirming occurrence of phenotype variations of Pseudomonas simiae EGD-AQ6 during chloroaromatic degradation. Furthermore, the sequence similarity of the 2-4-D catabolic genes and biofilm forming proteins (pel ABCDEFG and pga ABCD) which are responsible for building carbohydrate rich extracellular matrix, were significant with the respective organisms as revealed through genome analysis. This is the first report, which endorses this Pseudomonas simiae species to be unique in chloro-aromatic degradation through phenotype variation, thereby proving as a potential candidate in the improvement of bioremediation technologies.
Telerehabilitation program for older adults on a waiting list for physical therapy after hospital discharge: study protocol for a pragmatic randomized trial protocol
Authors: Borges Pollyana Ruggio Tristao , Resende Renan , Dias Jane Fonseca , Mancini Marisa Cotta , Sampaio Rosana Ferreira 
Published: June 2021

Abstract
Background: Delays in starting physical therapy after hospital discharge worsen deconditioning in older adults. Intervening quickly can minimize the negative effects of deconditioning. Telerehabilitation is a strategy that increases access to rehabilitation, improves clinical outcomes, and reduces costs. This paper presents the protocol for a pragmatic clinical trial that aims to determine the effectiveness and cost-effectiveness of a multi-component intervention offered by telerehabilitation for discharged older adults awaiting physical therapy for any specific medical condition.Methods: This is a pragmatic randomized controlled clinical trial with two groups: telerehabilitation and control. Participants (n=230) will be recruited among individuals discharged from hospitals who are in the public healthcare system physical therapy waiting lists. The telerehabilitation group will receive a smartphone app with a personalized program (based on individual’s functional ability) of resistance, balance, and daily activity training exercises. The intervention will be implemented at the individuals’ homes. This group will be monitored weekly by phone and monthly through a face-to-face meeting until they start physical therapy. The control group will adhere to the public healthcare system usual flow and will be monitored weekly by telephone until they start physical therapy. The primary outcome will be physical function (Timed Up and Go and 30-second Chair Stand Test). The measurements will take place in baseline, start, and discharge of outpatient physical therapy. The economic evaluations will be performed from the perspective of society and the Brazilian public healthcare system.Discussion: The study will produce evidence on the effectiveness and cost-effectiveness of multi-component telerehabilitation intervention for discharged older adult patients awaiting physical therapy, providing input that can aid implementation of similar proposals in other patient groups. Trial registration: Brazilian Clinical Trials Registry, RBR-9243v7. Registered on 24 August 2020.
Percutaneous Screw Fixation and Cementoplasty to Stabilize Unstable Osteolytic Fracture of Odontoid Process
Authors: Grange Loïc , Grange Rémi , Bertholon Sylvain , Morisson Stéphanie , Vassal Cécile , Tetard Marie-Charlotte , Grange Sylvain 
Published: June 2021

Abstract
Introduction: We relay a case of unstable lytic secondary fracture of odontoid process (C2) treated by screw fixation and cementoplasty, using a percutaneous approach. Case Presentation: A 62-year-old female patient followed for a breast neoplasia with bone concurrent metastases, suffered from diffuse cervical pain. A CT-scan showed a lytic fracture of C2. The procedure was performed using CT-scan guidance under general anesthesia. After a biphasic enhanced CT scan of the neck and cervical spine, a needle was slowly inserted to hydrodissect the jugulocarotid and prevertebral spaces up to the anterior cortex of C2 using an iodinated contrast agent solution diluted 5% with saline water. Under fluoroscopy guidance and intermittent CT monitoring, a bone pin was navigated though the anterior cortex of C2, and then advanced inside the vertebral body of C2. After checking for optimal positioning of the bone pin, a 34mm-long titanium screw was inserted into C2 until reaching the posterior cortex. The approach to the transverse fracture line of the body of the odontoid was tangential with no displacement of the bony parts. Cement injection was then performed. One month after the procedure, a CT scan showed no material displacement, and the patient had no visible skin scarring. The patient regained full mobility of the cervical spine, and the pain decreased from 7/10 before the procedure to 0/10 after the procedure according to the patient.Conclusion: Percutaneous screw fixation and cementoplasty to stabilize unstable osteolytic fracture of odontoid process is safe and feasible
Transcending the gain bandwidth limitation in semiconductors for full-colour-tunable lasers
Authors: Jiang Yi , Wei Qi , Li King Fai , Jin Mingke , Tam Hoi Lam , Li Guixin , Xing Guichuan , Cheah Kok Wai 
Published: June 2021

Abstract
Developing semiconductors with wide tunable gain bandwidth have always been at the forefront of laser technologies. The variation in feedback resonators can provide a useful tool for producing a relatively wide range of discrete lasing wavelengths. However, the lasing wavelength range is limited by the fundamental gain bandwidth of the single semiconductor itself. Full-colour range lasing through gain bandwidth tuning remains a daunting challenge. Here we demonstrate the feasibility of dynamically tuning amplification/lasing wavelengths in the entire emission spectrum by leveraging on Förster resonance energy transfer (FRET)-assisted guest-host blends. The unprecedented tunability in amplification and lasing is governed by energy transfer process, which enables us to achieve wavelength-tunable semiconductor lasers spanning the full visible region of the electromagnetic spectrum. Our distributed feedback lasers cover almost all CIE colour gamut (94%), which is 170% more perceptible colours than standard Red Green Blue colour space. These insights can guide the versatile and convenient design of semiconductor materials transcending current gain bandwidth limitation, paving the way for next generation of optoelectronic devices.
Applications of Jacobi’s Elliptic Functions in Forced Vibration in Nonlinear Rotor Dynamics
Authors: Ibrayev Gulama-Garip Alisher , Elishakoff Isaac , Kydyrbekuly Almatbek 
Published: June 2021

Abstract
In this paper studied a rotary system with a nonlinearity, the equations of motion of which is one of the types of the Duffing’s equations with multidegree-of-freedom, and also consider the advantages of using the elliptic function method to solve problems of this type. The system studied in this paper is also distinguished by the fact that in addition to the rotor vibrations in elastic supports with a nonlinearity, the vibrations of the foundation are also taken into account. The article presents a comparative analysis of the numerical Runge-Kutta-Fehlberg's 4-order method with an error estimate of 5-order, the approximate analytical Van der Pol’s method and the elliptic function method proposed by the authors by comparing the obtained equations of motion of the system, as well as by comparing the constructed frequency response characteristic. From the results obtained, it follows that the method proposed by the authors can serve as a more accurate, general case of previously used approximate methods.
Electronic, Optical and Vibrational Properties of B3N3H6 from First-Principles Calculations
Authors: Gan Yun-Dan , Qin Han , Liu Fu-Sheng , Liu Zheng-Tang , Jiang Cheng lu , Liu Qi-Jun 
Published: June 2021

Abstract
The electronic, optical and vibrational properties of B3N3H6 have been calculated by means of first-principles density functional theory (DFT) calculations within the generalized gradient approximation (GGA) and the local density approximation (LDA). The calculated structural parameters of B3N3H6 are in good agreement with experimental work. With the band structure and density of states (DOS), we have analyzed the optical properties including the complex dielectric function, refractive index, absorption, conductivity, loss function and reflectivity. By the contrast, it is found that on the (001) component and (100) component have obvious optical anisotropy. Moreover, the vibrational properties have been obtained and analyzed.
Integrated System for Recycling and Treatment of Hazardous Pharmaceutical Wastewater
Authors: El-Shamy Ashraf Moursi , Abdelfattah Ibrahim , Abuarab  , Mostafa Ehab , El-Awady  , Aboelghait Karim 
Published: June 2021

Abstract
This study aimed to investigate an integrated system that can deal with different pharmaceutical wastewater. Pharmaceutical wastewater was subjected to biological, chemical, and advanced oxidation according to its pollutant’s nature. Wastewater with high Total Suspended Solids (TSS 480 mg/l) was subjected to a conventional chemical treatment process utilizing different coagulants. The best results obtained by using Calcium Oxide and Alum aided with Calcium Oxide where, the removal efficiency of COD was 46.8% and 51 %. Highly loaded pharmaceutical wastewater (COD 9700 mg/l, BOD/COD 0.16) had been subjected to Fenton oxidation, removal of COD reached 80.4%, and the ratio of BOD/COD is enhanced to 0.6. Photocatalysis by using different nanomaterials was applied to pharmaceutical wastewater containing 10 mg/l of phenols. Phenol is completely removed by using Mesoporous TiO2 after 90 min irradiation and after 120 min in the case of TiO2/P25 and TiO2/UV 100 nanocomposites while it is removed by 40% in case of using Mesoporous TiO2/Ta2O5. Effluent treated water from previous routes was subjected to biological treatment and followed with disinfection by using UV as post-treatment. Final COD was 40 and it matches with Egyptian practice code for water reuse in agriculture. Results showed also using treated wastewater in irrigation of Barley and Bean seeds achieved germination ratio up to 71% in Barely and 70% in Bean compared with that irrigated with Nile water which reached 70% and 75%, while it was about 16.6% and 30% in case of irrigation with untreated wastewater.
Occurrence, Distribution and Risk Assessment of Heavy Metals in Agricultural Soil and Water Around a Lead-zinc Mine in Southwest China
Authors: Jiang Yunchuan , Li Hanhan , Li Zhijian , Liu Yongfu , Li Zhiqiang , Shao Jirong , Zhang Xiaohong , Yang Yuanxiang , Yang Zhanbiao , Wang Chenglong , Zhu Xuemei 
Published: June 2021

Abstract
Mining activities could induce severe heavy metal pollution in soil and surface water, which would consequently pose potential ecological environment risks and human health risks. In this research, total 82 agricultural soil samples and 34 water samples were collected from a special area that surrounding a lead-zinc mine. Pollution level, source apportionment, ecological and health risks of heavy metals were evaluated based on the concentrations of cadmium (Cd), chromium (Cr), copper (Cu), manganese (Mn), nickel (Ni), lead (Pb) and zinc (Zn). According to the results, Cd and Zn were obviously enriched metals in agricultural soil in the study area, meanwhile, the potential risks which calculated by geo-accumulation index were showed a high ecological risk due to high concentration of Cd found in local agricultural soil. Additionally, heavy metal sources analyzed by the PMF model could be classified into four categories: mining activity (Mn), parent material (Cr, Ni), atmospheric deposition caused by industrial and mining activities (Pb, Zn, Cd) and agricultural activities (Cu). Compared with the values specified by corresponding water quality standard, the heavy metals content in surface water were below these values except Cd, while the content of seven heavy metals in drinking water was within the safe limits. The bioavailability of Cd, Pb and Zn in soil were higher than other metals, and when the bioavailability of metals was consideration into health risk assessment, the total HI and TCR values were far below the accepted risk levels. Though human health risks were within the safe margin, the toxic hazards of heavy metals to residents and ecological should be taken into consideration.
Structure-based Assessment of Homologous Analogues of NAtural products -SAHANA: A novel approach to screen bioactive compounds in comparison with their synthetic drug counterparts
Authors: Rao Aditya , Shetty Nandini 
Published: June 2021

Abstract
Background The present study describes a novel strategy to screen natural products (NPs) for their therapeutic effects with predicted most-probable mode of action. The method entitled ‘Structure-based Assessment of Homologous Analogues of NAtural products-SAHANA’ follows a strategy to compare natural products against synthetic drugs based on their molecular properties and 2-dimensional structural similarities. The method is based on a well-established hypothesis that, the molecules with similar structural properties will have similar functions.Methods The method was validated by implementing it for the screening of NPs against different disease conditions. The biological effect of the identified NPs were evaluated based on their binding affinity with the target of their synthetic drug counterpart, prior to which, their in-silico pharmacokinetic and pharmacodynamics properties were assessed. The stability of binding was validated using molecular dynamics simulation studies.Results The study yielded NPs with significant structural similarities to synthetic drugs and binding interactions stabilizing the macromolecular structures.Conclusions The results envisage a strong indication that the natural product drugs can work in a manner similar to that of synthetic drugs if administered individually. Further, the results encourage the application of the current strategy to screen competent drugs against any disease condition ad libitum.