bluuebunny/crossref_metadata_2025_split huggingface dataset:
HEALTH-RELATED QUALITY OF LIFE OF HEALTH PROFESSIONALS IN A TERTIARY HEALTH INSTITUTION OF SOUTHWESTERN NIGERIA: A CROSS-SECTIONAL SURVEY
Authors: Odetunde M. O. , Ajibola B. O. , Ilesanmi O. T. , Okonji A. M. , Ojoawo A. O. , Awotidebe T. O. , Odetunde N. A. , Omisore O. B. , Mbada C. E. 
Published: August 2021

Introduction: Health professionals (HP) are frequently exposed to a high number of hazards at the workplace. Consequently, low ratings for their well-being and satisfaction with health care may adversely affect the quality of health services they provide. This study aimed to assess health-related quality of life (HRQOL) and determine the effects of socio-demographic variables on HRQOL across HP in a tertiary health institution in Nigeria, a low-middle-income economy. Method: This was a cross-sectional survey of 385 HP purposively recruited from different units of Obafemi Awolowo University Teaching Hospital (OAUTH), Ile-Ife, Nigeria. All respondents completed the Medical Outcomes Study short-form (SF-36) questionnaire. Also, the socio-demographic information on the respondents was obtained. Descriptive statistics of mean, standard deviation, frequency and percentages; and inferential statistics of independent t-test and one way ANOVA was used to analyze data. Alpha level was set at p<0.05. Results: Respondents comprised 273 males and 112 females. They scored well above the cut-off point of 50 in most subscales with higher physical (80.95±12.03) than mental (67.58±7.88) component score on SF-36. There were significant differences between gender in favour of male respondents with the highest mean score across each of the age groups, educational and professional qualifications (p<0.01) on most subscales. Conclusion: There are considerable inequalities in HRQOL among HP in this study. These inequalities are gender-biased and favour professionals with post-graduate degree. Findings from this study are comparable to other climes and advocate support for female HP, those on low cadre and higher degree training.
Periapical Radiograph has a High Accuracy and an Alternative Imaging Modality in the Third Molar Impaction Cases
Authors: Yueniwati Yuyun , Subiantoro Yolan Bianika , Fidya Fidya 
Published: August 2021

Introduction: Impaction is a condition when a tooth suffers from a complete eruption failure on its right position due to the lack of curvace room on the jaw. Periapical radiography has an important role in detecting third molar impaction disease. Recently, panoramic radiograph has become the standard in diagnosing the third molar impaction.
Objective: The objective set for this study is to evaluate the accuracy of the periapical radiograph based on the standard which is the panoramic radiograph on the third molar impaction cases.Materials and Method: This study belongs to that of analytic observational by employing diagnostic testing method on primary data. It employed 35 samples which were then cross tabulated using 2x2 analysis table.The result of the grouping was then inserted into the formula for sensitivity, spesificity, positive predictive value, negative productive value, accuracy and ROC graphic.
Result: The result of this study shows that the score for sensitivity reaches 96%, 33.3% for spesificity, 80.6% for positive predictive value, 75% for negative predictive value, 80% for accuracy, and 77.8% for ROC graphic. Conclusion: periapical radiograph can be used as an alternative checking up in diagnosing third molar impaction cases. However, it is not used as a panoramic substitute which still serves as the standard.
KAJIAN NOVEL AWAL LAYUNYA MAWAR BERDURI KARYA TULUS SETIYADI DALAM PERSPEKTIF PSIKOLOGI SASTRA
Authors: Baekuniah  , Onok Yayang Pamungkas  
Published: August 2021

As one form of attention to literary works (novels), researcher interested in studying / analyzing a novel entitled Awal Layunya Mawar Berduri by Tulus Setiyadi. This study aims to 1) explain and describe the structure of the novel, 2) the inner conflicts of the main female characters, and 3) the value of character education in these. To achieve this goal, researcher analyzed the intrinsic elements of the novel related to the psychology of literature. Literary psychology approach used Sigmund Freud's personality theory, and the value of character education refers to Lifelong Guidelines and Character First. The results of this study are. 1) Awal Layunya Mawar Berduri was a novel that groves forward. The story moved based on the time sequence until the end of a story that in the end was sad ending, which is the death of the character Asih. 2) Representation of literary psychology in the Novel Awal Layunya Mawar Berduri found through the aspects of id, ego and superego. 3) The value of Character Education based on Lifelong Guidelines and character first. The conclusion of this research was that the researcher studied Asih's personal character in the Novel Awal Layunya Mawar Berduri used the psychological psychology approach, so the researcher found the personality of Asih's character that distinguishes it from other figures. Awal Layunya Mawar Berduri became an interesting study material, because this novel explores the lives of Asih characters continuously with a storyline that involves the personalities of all the characters. Of the various types of personalities possessed by each character, causing conflict with the character. The methods used by Asih's characters in resolving various conflicts, there is the value of character education that can be used as an example for the reader of the Novel Awal Layunya Mawar Berduri. An important implication of this research is that literature in a psychological perspective gives rise to the values ??of character education that can guide the reader so they can have an attitude of responsibility, integrity, patience, fortitude, and self-control in living life.
Memorias y lugares de desaparición: las declaraciones públicas de los perpetradores de la ESMA en Argentina
Authors: Feld Claudia Viviana , Salvi Valentina Isolda 
Published: August 2021

La Escuela de Mecánica de la Armada (ESMA), uno de los centros clandestinos de detención más activos de la última dictadura militar (1976-1983), se ha constituido, mediante un complejo proceso memorial, en un emblema de la represión más atroz. Este proceso memorial involucró una serie “capas” de sentido, que fueron desarrollándose en función de acciones, narrativas y debates sostenidos por diversos actores. El presente artículo se centra en un aspecto específico y poco estudiado, aunque no menor, de dicho proceso: las narrativas y acciones producidas por perpetradores de la ESMA. Nuestro trabajo analiza las declaraciones públicas del cabo Raúl Vilariño, a inicios de la transición (1984), y las del capitán Adolfo Scilingo, en un período de impunidad (1995). Se observa de qué manera, en esos dos momentos, la palabra pública de estos represores incidió en la visibilización del sitio, en la calificación del crimen y de la “escena del crimen”, y en la conformación de una verdad social. Este análisis permite comprender dos procesos centrales del trabajo memorial: por un lado, la disputa por la legitimación de un punto de vista; por otro, el “proceso de emblematización” del lugar. Se trata, en definitiva, de una lenta construcción a partir de la cual la ESMA se fue interpretando no sólo como una particular “escena del crimen” de la desaparición de personas, sino también como una figura metonómica y emblemática que designa el conjunto de los centros clandestinos donde se perpetró el horror.
Palabras clave: Perpetradores; dictadura; sitios de memoria; declaraciones.
The Gender Role Attitude Scale (GRAS) as an alternative for the crisis in measurement of attitudes towards gender roles in Latin America: A study in Chilean university students
Authors: Pérez Sánchez Beatriz , Concha-Salgado Andrés , Fernández-Suárez Asunción , Juarros-Basterretxea Joel , Rodríguez-Díaz Francisco Javier 
Published: August 2021

Hemos experimentado cambios socioculturales que han favorecido el desarrollo de actitudes de roles de género (GRA) más igualitarias. Sin embargo, actualmente la revolución en los roles de género está incompleta y la falta de equidad en las estructuras sociales limita las experiencias individuales en igualdad. Ante esta realidad, la comunidad científica exige un sistema modernizado para medir GRA. Presentamos adaptación, evidencia de validez factorial y convergente, precisión, efecto techo y piso, normas de interpretación por sexo, y análisis del GRA más fácil y difícil de modificar, para la Escala de Actitudes de Rol de Género (EARG) en muestra de 1013 universitarios chilenos. La EARG tiene una estructura bifactorial que evalúa actitudes estereotipadas y trascendentes en contextos familiares, sociales y laborales. Presenta validez convergente con una medida de doble estándar sexual y es más confiable en puntajes bajos de trascendencia y puntajes altos de actitudes estereotipadas. El factor trascendente tuvo un efecto techo, y las actitudes estereotipadas un efecto suelo. Los roles familiares de género son los más fáciles de cambiar, y los relacionados con el trabajo los más difíciles. Se discute la necesidad de un cambio estructural para reactivar la revolución de los roles de género en Chile.
We have experienced sociocultural changes, which have favoured the development of egalitarian gender role attitudes (GRA). Nevertheless, the revolution in gender roles is incomplete, and the lack of equity in social structures limits the individual experiences in equality. In the face of this reality, the scientific community is demanding a modernised system for measuring GRA. We present adaptation, evidence of factorial and convergent validity, accuracy, ceiling and floor effect, norms of interpretation by sex, and analyses of the GRA easiest or most difficult to modify, for the Gender Role Attitudes Scale (GRAS) in a sample of 1013 Chilean university students. The GRAS has a two-factor structure that allows the evaluation of stereotyped and transcendent attitudes of gender roles in family, social, and work contexts. The scale presents convergent validity with a sexual double standard measure and is more reliable in the low scores of transcendence and the high scores of stereotyped attitudes. Transcendent factor had a ceiling effect, and stereotyped attitudes had a floor effect. Family gender roles are the easiest to change, and work-related roles the most difficult. The authors discuss the need for a structural change to reactivate the revolution of gender roles in Chile.
From randomized control trial to mixed methods: A practical framework for program evaluation based on methodological quality
Authors: Chacón-Moscoso Salvador , Sanduvete-Chaves Susana , Lozano-Lozano José A. , Portell Mariona , Anguera M. Teresa 
Published: August 2021

La evidencia utilizada al tomar decisiones sobre el diseño, implementación y evaluación en los programas de intervención debe ser metodológicamente sólida. Dependiendo del contexto de la intervención, se pueden aplicar diferentes metodologías. Sin embargo, el contexto de la intervención es a menudo inestable y, para adaptarse a las circunstancias cambiantes, se hace necesario modificar el plan original. El marco propuesto en este documento se basa en enfoques que pueden considerarse dos extremos de un continuo (diseños experimentales / cuasiexperimentales y estudios basados en metodología observacional). En condiciones de contexto de intervención inestable, esto permite tomar decisiones desde un enfoque de calidad metodológica en cuanto a diseño, medición y análisis. Las dimensiones estructurales, i.e., las unidades (participantes, usuarios), el tratamiento (actividades del programa), los resultados (incluidas las decisiones sobre los instrumentos a utilizar y la recopilación de datos), el entorno (contexto de implementación) y el tiempo se detallarán como parte del marco práctico. El presente estudio tiene como objetivo especificar el grado de correspondencia / complementariedad entre componentes en estas dimensiones estructurales de la evaluación de un programa desde una perspectiva de complementariedad práctica basada en la calidad metodológica.
The evidence used when making decisions about the design, implementation and evaluation in intervention programs should be methodologically sound. Depending on the context of the intervention, different methodologies may apply. Nonetheless, the intervention context is often unstable and, to adapt to changing circumstances, it sometimes becomes necessary to modify the original plan. The framework proposed herein draws on approaches that can be considered two extremes of a continuum (experimental/quasi-experimental designs and studies based on observational methodology). In unstable intervention context conditions, this enables decisions from a methodological quality approach regarding design, measurement, and analysis. Structural dimensions, i.e., units (participants, users), treatment (program activities), outcomes (results, including decisions about the instruments to use and data gathering), setting (implementation context) and time will be detailed as part of the practical framework. The present study aims to specify the degree of correspondence/complementarity between components in these structural dimensions of a program evaluation from a practical complementarity perspective based on methodological quality.
A proteome-wide genetic investigation identifies several SARS-CoV-2-exploited host targets of clinical relevance
Authors: Anisul Mohd , Shilts Jarrod , Schwartzentruber Jeremy , Hayhurst James , Buniello Annalisa , Shaikho Elhaj Mohammed Elmutaz , Zheng Jie , Holmes Michael , Ochoa David , Carmona Miguel , Maranville Joseph , Gaunt Tom R , Emilsson Valur , Gudnason Vilmundur , McDonagh Ellen M , Wright Gavin J , Ghoussaini Maya , Dunham Ian 
Published: August 2021

Background:The virus SARS-CoV-2 can exploit biological vulnerabilities (e.g. host proteins) in susceptible hosts that predispose to the development of severe COVID-19.Methods:To identify host proteins that may contribute to the risk of severe COVID-19, we undertook proteome-wide genetic colocalisation tests, and polygenic (pan) and cis-Mendelian randomisation analyses leveraging publicly available protein and COVID-19 datasets.Results:Our analytic approach identified several known targets (e.g. ABO, OAS1), but also nominated new proteins such as soluble Fas (colocalisation probability >0.9, p=1 × 10-4), implicating Fas-mediated apoptosis as a potential target for COVID-19 risk. The polygenic (pan) and cis-Mendelian randomisation analyses showed consistent associations of genetically predicted ABO protein with several COVID-19 phenotypes. The ABO signal is highly pleiotropic, and a look-up of proteins associated with the ABO signal revealed that the strongest association was with soluble CD209. We demonstrated experimentally that CD209 directly interacts with the spike protein of SARS-CoV-2, suggesting a mechanism that could explain the ABO association with COVID-19.Conclusions:Our work provides a prioritised list of host targets potentially exploited by SARS-CoV-2 and is a precursor for further research on CD209 and FAS as therapeutically tractable targets for COVID-19.Funding:MAK, JSc, JH, AB, DO, MC, EMM, MG, ID were funded by Open Targets. J.Z. and T.R.G were funded by the UK Medical Research Council Integrative Epidemiology Unit (MC_UU_00011/4). JSh and GJW were funded by the Wellcome Trust Grant 206194. This research was funded in part by the Wellcome Trust [Grant 206194]. For the purpose of open access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission.
Enrichment of Therapeutically Significant Flavonolignans of Silybum Marianum in Vegetative Parts by Applying Fungal Elicitors, Methyl Jasmonate and Silver Nanoparticles as Elicitor in Hydroponic Culture
Authors: Mubeen Bismillah , Ali Qurban , Hasnain Ammarah , Malik Arif 
Published: August 2021

Introduction: Medicinal plants are being used to treat several diseases for many decades and this is an ancient method to treat the patients. Herbal plant Silybum marianum found most effective one to cure liver disorders. This plant produces silymarin which is a secondary metabolite and have hepatoprotective properties. Silymarin is a mixture of flavonolignans (silybin A, silybin B, isosilybin A isosilybin B, silychristin, silydianin apigenin 7-D glucose and taxifolin) that has antiviral, antibacterial, antifungal and antiallergenic properties. Therefore, the excessive production of silymarin is necessary to cure different types liver disorders, so the present study executed to boost up production of Silymarin flavonolignans in vegetative parts of the Silybum marianum plant by using different elicitors.
Materials and Methods: In the present study, elicitation technique in hydroponics system was used to enhance the production of pharmacologically active flavonolignans in Silybum marianum. Fungal elicitors prepared from lyophilized Aspergillus niger biomass, methyl jasmonate, silver nanoparticles and combination of silver nanoparticles and methyl jasmonate were added (0.2g/l), (100µM/l), (1 ppm) and (100µM/lppm) in hydroponics with Hoagland’s solution in hydroponics to enhance the production of flavonolignans of Silybum marianum. Controls were also set for each treatment. Plants were harvested after 72 hours of introduction of elicitors. High performance liquid chromatography technique was used for analytical purpose. Four solvents (methanol, acetonitrile, chloroform and 2% Trifloro acetic acid) were used in HPLC. Column was C18 and run time of sample was 1 hour. Silybum marianum’s seed extract was used as a standard. Extract of control and treated plants were run on the same polarity in HPLC.
Results: Results showed that after elicitation significant increase was observed in production of silymarin’s flavonolignans (silybin A, silybin B, isosilybin A, isosilybin B and apigenin 7-D glucose) in vegetative part of the plant but rate of production was different for each elicitor, fungal elicitors prepared from lyophilized Aspergillus niger biomass proved best among all treatments.
Dielectric Constant Engineering of Organic Semiconductors: Effect of Planarity and Conjugation Length
Authors: Jiang Wei , Jin Hui , Babazadeh Mohammad , Loch Alex S. , Raynor Aaron , Mallo Neil , Huang David M. , Jiao Xuechen , Tan Wen Liang , McNeill Christopher R. , Burn Paul L. , Shaw Paul E. 
Published: August 2021

AbstractBulk heterojunction organic solar cells continue to show steady photoconversion efficiency improvements. However, single component organic solar cells are a particularly attractive alternative due to the relative simplicity of device manufacture. It has been proposed that organic semiconductors with a high dielectric constant (≈10) could give rise to spontaneous free charge carrier generation upon photoexcitation. In this manuscript, factors are explored that affect the dielectric constant of organic semiconductors, particularly the optical‐frequency dielectric constant. The properties of monomers, dimers and trimers of two isoelectronic families of materials that have acceptor units composed of one or two dicyanovinylbenzothiadiazole moieties and one to three donor units are compared. The donor components are composed of either fluorenyl or cyclopentadithiophene moieties with the same glycol‐based solubilizing groups. It is found that chromophore planarity and orientation with respect to the substrate, and film density affect the optical and electronic properties of the materials, especially the high‐frequency dielectric constant. The results also indicate that delocalization of the highest occupied and lowest unoccupied molecular orbitals is a critical factor. The dimer with two dicyanovinylbenzothiadiazole moieties and two dithienocyclopentadiene units is found to have the highest optical frequency dielectric constant and overall performance.
Conformational Freedom‐Enhanced Optomechanical Energy Conversion Efficiency in Bulk Azo‐Polyimides
Authors: Zhai Chenxi , Lin Shangchao , Wang Mingchao , Zhou Huanhuan , Stanisauskis Eugenia , Cai Zhuangli , Yeo Jingjie , Oates William 
Published: August 2021

AbstractAzobenzene‐doped glassy polyimides (azo‐polyimides) offer some of the most efficient optomechanical power densities to date rivaling electrostrictive polymers. Despite such potential attributes, the optomechanical efficiency remains low in comparison to other smart materials. Using high‐fidelity coarse‐grained molecular dynamics simulations, the authors reconcile both experimental and theoretical challenges to understand the limiting factors for the optomechanical conversion in photostrictive polymers. Interestingly, the ideal optomechanical efficiency of 10–24% for a single‐chain azo‐imide monomer predicted here is equal to or a little higher than experimental reports, suggesting experimental design space. The time‐dependent optomechanical efficiency of bulk azo‐polyimide is quantified, for the first time, to be strongly correlated with the initial free volumes, a measure of polymer conformational freedom. This trend is elaborated by conformational order parameters and viscoelastic relaxation moduli. Resembling the role of porosity in azobenzene‐contained metal/covalent organic frameworks to enhance the photo‐switching efficiency, a larger conformational freedom enables >10 times increase in optomechanical efficiency comparing to existing experiments. This is primarily due to facilitated viscoelastic relaxation after photo‐switching which alleviates residual stresses quickly and reduces heat dissipation. These findings suggest opportunities to improve the optomechanical performance through targeted strategies, such as porosity control and thermal annealing.
Sunlight‐Sensitive Plasmonic Nanostructured Composites as Photocatalytic Coating with Antibacterial Properties
Authors: Marín‐Caba Laura , Bodelón Gustavo , Negrín‐Montecelo Yoel , Correa‐Duarte Miguel A. 
Published: August 2021

AbstractInfections caused by microorganisms are a global public health problem that continually demands new antimicrobial strategies. The generation of reactive oxygen species (ROS) by photocatalytic materials is an attractive approach to combat microbes. Along these lines, titanium dioxide (TiO2) constitutes an outstanding light‐driven ROS generator. However, the wide bandgap of this semiconductor limits its use to the ultraviolet range of the spectral region. Herein, nanostructured materials composed of TiO2 nanoparticles and plasmonic gold nanorods (AuNRs) are presented for the photoinactivation of bacteria by means of sunlight irradiation, aiming to extend the photocatalytic action of the nanocomposite to the visible and near‐infrared ranges. It is shown that, upon simulated sunlight irradiation, the different composites as coating films show photodegradation of rhodamine B, ROS production, photocatalytic inactivation of protein function in bacterial biofilms, and strong antimicrobial activity. This approach involving AuNRs/TiO2 photocatalytic composites may pave the way for the fabrication of visible light‐responsive surfaces with antimicrobial activity.