bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magnetosensitive E‐Skins for Interactive Devices
Authors: Cañón Bermúdez Gilbert Santiago , Makarov Denys 
Published: February 2021

AbstractElectronic skins (e‐skins) have established themselves as a versatile technology to restore or enhance human perception, and potentially enable softer robotics. So far, the focus has been mostly on reproducing the traditional functions associated with human skin, such as, temperature, pressure, and chemical detection. New developments have also introduced nonstandard sensing capabilities like magnetic field detection, to spawn the field of magnetosensitive e‐skins. Adding a supplementary information channel—an electronic sixth sense—allows humans to utilize the surrounding magnetic fields as stimuli for touchless interactions. Due to their vectorial nature, these stimuli can be used to track motion and orientation in 3D, opening the door to various kinds of gestural control for interactive devices. This approach to tracking provides an alternative or complement to optic‐based systems, which usually rely on cameras or infrared emitters, that cannot easily capture fine motion when objects are far from the source or the line‐of‐sight is obtruded. Here, the background, fabrication techniques, and recent advances of this field are reviewed; covering important aspects like: directional perception, geomagnetic field detection, on‐site conditioning, and multimodal approaches. The aim is to give the reader a general perspective and highlight some new avenues of research, toward artificial magnetoception.
Double Charge Transfer Dominates in Carrier Localization in Low Bandgap Sites of Heterogeneous Lead Halide Perovskites
Authors: Fakharuddin Azhar , Franckevičius Marius , Devižis Andrius , Gelžinis Andrius , Chmeliov Jevgenij , Heremans Paul , Gulbinas Vidmantas 
Published: February 2021

AbstractHeterogeneous organic‐inorganic halide perovskites possess inherent non‐uniformities in bandgap that are sometimes engineered and exploited on purpose, like in quasi‐2D perovskites. In these systems, charge carrier and excitation energy migration to lower‐bandgap sites are key processes governing luminescence. The question, which of them dominates in particular materials and under specific experimental conditions, still remains unanswered, especially when charge carriers comprise excitons. In this study transient absorption (TA) and transient photoluminescence (PL) techniques are combined to address the excited state dynamics in quasi‐2D and other heterogeneous perovskite structures in broad temperature range, from room temperature down to 15 K. The data provide clear evidence that charge carrier transfer rather than energy migration dominates in heterogeneous quasi‐2D perovskite films.
Microneedle Patch Delivery of Capsaicin‐Containing α‐Lactalbumin Nanomicelles to Adipocytes Achieves Potent Anti‐Obesity Effects
Authors: Bao Cheng , Li Zekun , Liang Shuang , Hu Yulin , Wang Xiaoyu , Fang Bing , Wang Pengjie , Chen Shanan , Li Yuan 
Published: February 2021

AbstractThe development of a minimally invasive therapy for local targeting of adipose tissues could represent an attractive approach for treating obesity. Here, the development and successful application of a nanomedicine that uses α‐lactalbumin (α‐lac) nanomicelles (M) to encapsulate the known anti‐obesity agent capsaicin (Cap), which is delivered directly to adipose tissue via a microneedle patch (MP), is reported. Testing with a 3T3‐L1 adipocyte model shows that M (Cap) reduces lipid droplet content by regulating adipogenesis and improving mitochondrial biogenesis. The MP enables efficient M (Cap) penetration into abdominal subcutaneous adipose tissue, and M (Cap) can be endocytosed by white adipocytes. Experiments using a high fat diet‐induced obese mice model shows that MP‐delivered M (Cap) confers dramatic weight loss and adipose tissue browning, and follow‐up mechanistic investigations indicate (among other impacts) activated energy metabolism, increased mitochondrial biogenesis, and the induction of well‐known adipocyte browning markers. The study supports that MP‐M (Cap) treatment, which could be developed as a self‐administered therapy based on skin attachment for around 30 min, has a promising future as a non‐invasive approach for treating obesity.
MXene‐ZnO Memristor for Multimodal In‐Sensor Computing
Authors: Wang Yan , Gong Yue , Yang Lin , Xiong Ziyu , Lv Ziyu , Xing Xuechao , Zhou Ye , Zhang Bing , Su Chenliang , Liao Qiufan , Han Su‐Ting 
Published: February 2021

AbstractRecently, in‐sensor computing with individual sensors or multiple connected sensors directly processing information has been proposed to improve energy, area, and time efficiency of artificial intelligence systems. Current investigations mainly focus on a single sensory processing such as auditory, visual, tactile, olfactory, and so on. However, a human perception system can sense and process different types of information with a complex environment and small perceptive field simultaneously. For example, the recognition accuracy of human eyes is highly affected by the environment such as extremely low or high relative humidity (RH). Here, a multi‐modal MXene‐ZnO memristor that combines visual data sensing, RH sensing, and pre‐processing functions to emulate the unique environmental adaptive behavior of the human eye is designed and constructed. The multi‐field controlled resistive switching of the MXene‐ZnO memristor is originated from the photon‐/protons‐regulated formation of oxygen vacancies filaments. Finally, in‐sensor computing with a MXene‐ZnO memristor functioning as both filter to preprocess the information and synapse to implement a weight updating process with different humidity adaptability has been demonstrated. Multimodal in‐sensor computing provides the potential to reduce the underlying circuitry complexity of the traditional neuromorphic visual system and contributes to the development of intelligence in device‐level implementations.
Multiscale Structural Modulation of Anisotropic Graphene Framework for Polymer Composites Achieving Highly Efficient Thermal Energy Management
Authors: Dai Wen , Lv Le , Ma Tengfei , Wang Xiangze , Ying Junfeng , Yan Qingwei , Tan Xue , Gao Jingyao , Xue Chen , Yu Jinhong , Yao Yagang , Wei Qiuping , Sun Rong , Wang Yan , Liu Te‐Huan , Chen Tao , Xiang Rong , Jiang Nan , Xue Qunji , Wong Ching‐Ping , Maruyama Shigeo , Lin Cheng‐Te 
Published: February 2021

AbstractGraphene is usually embedded into polymer matrices for the development of thermally conductive composites, preferably forming an interconnected and anisotropic framework. Currently, the directional self‐assembly of exfoliated graphene sheets is demonstrated to be the most effective way to synthesize anisotropic graphene frameworks. However, achieving a thermal conductivity enhancement (TCE) over 1500% with per 1 vol% graphene content in polymer matrices remains challenging, due to the high junction thermal resistance between the adjacent graphene sheets within the self‐assembled graphene framework. Here, a multiscale structural modulation strategy for obtaining highly ordered structure of graphene framework and simultaneously reducing the junction thermal resistance is demonstrated. The resultant anisotropic framework contributes to the polymer composites with a record‐high thermal conductivity of 56.8–62.4 W m−1 K−1 at the graphene loading of ≈13.3 vol%, giving an ultrahigh TCE per 1 vol% graphene over 2400%. Furthermore, thermal energy management applications of the composites as phase change materials for solar‐thermal energy conversion and as thermal interface materials for electronic device cooling are demonstrated. The finding provides valuable guidance for designing high‐performance thermally conductive composites and raises their possibility for practical use in thermal energy storage and thermal management of electronics.
Paired soil and rice arsenic and cadmium from northeastern U.S. rice farms
Authors: Hu Ruifang , Teasley William A. , Seyfferth Angelia L. 
Published: February 2021

AbstractArsenic (As) and cadmium (Cd) are two toxic elements found in rice (Oryza sativa L.) grain that pose threats to human health. While attention has focused on major rice‐growing regions, rice has been grown on small‐scale farms in the northeastern United States since approximately 2005, but the grain As and Cd levels were not previously reported. Unpolished grain from these farms have mean As of 0.12 mg kg−1 and mean Cd of 0.007 mg kg−1, more than 40% lower than previously reported in U.S. rice. Therefore, rice from these farms poses low risk for consumers.
Calendar Life of Zn Batteries Based on Zn Anode with Zn Powder/Current Collector Structure
Authors: Li Qing , Wang Yanbo , Mo Funian , Wang Donghong , Liang Guojin , Zhao Yuwei , Yang Qi , Huang Zhaodong , Zhi Chunyi 
Published: February 2021

AbstractZn foil is widely used for studying the stability and dendrite formation behavior of Zn anodes. The reported long cycling life of rechargeable Zn batteries (RZBs) is obtained by testing a battery immediately after its fabrication neglecting the aging effects. The cycling performance demonstrated cannot, however, have practical applications. Using Zn foil as both the working electrode and current collector will cause many problems when the battery is scaled up. A Zn powder (Zn‐P)/current collector configuration is more practical. In this work, the corrosion of the Zn‐P@Cu anode‐induced cell swelling is first quantitatively studied. During the aging process of the Zn‐P@Cu electrode, hydrogen forms on the surface of Cu and the Zn‐P dissolves resulting in morphological changes. These phenomena can be attributed to galvanic corrosion between Cu and Zn. To address this issue, tin with a higher overpotential for hydrogen generation is plated on Cu surface. The results indicate that hydrogen evolution is ameliorated. With a low NP ratio (mass) of 10:7, considerably better storage and cycling performance are achieved for Zn‐P@Cu//MnO2. These results highlight the need to focus on the calendar life of RZBs and corrosion of the Zn anode.
Upgrading the evidence for the use of ambroxol in Gaucher disease and GBA related Parkinson: Investigator initiated registry based on real life data
Authors: Istaiti Majdolen , Revel‐Vilk Shoshana , Becker‐Cohen Michal , Dinur Tama , Ramaswami Uma , Castillo‐Garcia Daniela , Ceron‐Rodriguez Magdalena , Chan Alicia , Rodic Predrag , Tincheva Radka Stefanova , Al‐Hertani Walla , Lee Beom Hee , Yang Chia‐Feng , Kiec‐Wilk Beata , Fiumara Agata , Rubio Barbara , Zimran Ari 
Published: February 2021

AbstractAmbroxol hydrochloride is an oral mucolytic drug available over‐the‐counter for many years as cough medicine. In 2009 it was identified as a pharmacological chaperone for mutant glucocerebrosidase, albeit in a several‐fold higher dose. Unfortunately, there have been no pharma‐driven clinical trials to establish its use. Thus, real‐world observational data are needed on the safety and efficacy of ambroxol for patients with Gaucher disease (GD) and GBA‐Parkinson disease (GBA‐PD). Clinicians treating patients with ambroxol for GD and GBA‐PD were approached to collaborate in an investigator‐initiated registry. Anonymized data were collected, including demographics, GD type, GD‐specific therapy (when applicable), adverse events (AEs), and, when available, efficacy data. We report the data of the first 41 patients (25 females) at a median (range) age 17 (1.5–74) from 13 centers; 11 with GD type 1(four diagnosed with PD), 27 with neuronopathic GD (nGD), and three GBA mutation carriers with PD. The median (range) treatment period and maximum dose of ambroxol were 19 (1–76) months and 435 (75‐1485) mg/day, respectively. One patient with type 2 GD died of her disease. No other severe AEs were reported. Twelve patients experienced AE, including minor bowel discomfort, cough, allergic reaction, mild proteinuria, dizziness and disease progression. Clinical benefits were reported in 25 patients, including stable or improved neurological status, increased physical activity, and reduced fatigue. Until the approval of specific therapies for nGD and disease‐modification for GBA‐PD, these preliminary data may be encouraging to physicians and patients who consider an off‐label use of ambroxol.
Prediction of postpartum hemorrhage in pregnant women with immune thrombocytopenia: Development and validation of the MONITOR model in a nationwide multicenter study
Authors: Huang Qiu‐Sha , Zhu Xiao‐Lu , Qu Qing‐Yuan , Liu Xiao , Zhang Gao‐Chao , Su Yan , Chen Qi , Liu Feng‐Qi , Sun Xue‐Yan , Liang Mei‐Ying , Liu Yi , Jiang Ming , Liu Hui , Feng Ru , Yao Hong‐Xia , Zhang Lei , Qian Shen‐Xian , Yang Tong‐Hua , Zhang Jing‐Yu , Shen Xu‐Liang , Yang Lin‐Hua , Hu Jian‐Da , Huang Ren‐Wei , Jiang Zhong‐Xing , Wang Jing‐Wen , Zhang Hong‐Yu , Xiao Zhen , Zhan Si‐Yan , Liu Hui‐Xin , Chang Ying‐Jun , Jiang Qian , Jiang Hao , Lu Jin , Xu Lan‐Ping , Zhang Xiao‐Hong , Yin Cheng‐Hong , Wang Jian‐Liu , Huang Xiao‐Jun , Zhang Xiao‐Hui 
Published: February 2021

AbstractGlobally, postpartum hemorrhage (PPH) is the leading cause of maternal death. Women with immune thrombocytopenia (ITP) are at increased risk of developing PPH. Early identification of PPH helps to prevent adverse outcomes, but is underused because clinicians do not have a tool to predict PPH for women with ITP. We therefore conducted a nationwide multicenter retrospective study to develop and validate a prediction model of PPH in patients with ITP. We included 432 pregnant women (677 pregnancies) with primary ITP from 18 academic tertiary centers in China from January 2008 to August 2018. A total of 157 (23.2%) pregnancies experienced PPH. The derivation cohort included 450 pregnancies. For the validation cohort, we included 117 pregnancies in the temporal validation cohort and 110 pregnancies in the geographical validation cohort. We assessed 25 clinical parameters as candidate predictors and used multivariable logistic regression to develop our prediction model. The final model included seven variables and was named MONITOR (maternal complication, WHO bleeding score, antepartum platelet transfusion, placental abnormalities, platelet count, previous uterine surgery, and primiparity). We established an easy‐to‐use risk heatmap and risk score of PPH based on the seven risk factors. We externally validated this model using both a temporal validation cohort and a geographical validation cohort. The MONITOR model had an AUC of 0.868 (95% CI 0.828–0.909) in internal validation, 0.869 (95% CI 0.802–0.937) in the temporal validation, and 0.811 (95% CI 0.713–0.908) in the geographical validation. Calibration plots demonstrated good agreement between MONITOR‐predicted probability and actual observation in both internal validation and external validation. Therefore, we developed and validated a very accurate prediction model for PPH. We hope that the model will contribute to more precise clinical care, decreased adverse outcomes, and better health care resource allocation.
Centring migrant community voices in forced marriage prevention social policy: A proposed reframing
Authors: Zeweri Helena , Shinkfield Sara 
Published: February 2021

AbstractIn this article, we examine how young adult Muslim Australian women from immigrant families are navigating familial pressures around marriage, and what this can teach the forced marriage prevention sector about the importance of privileging community voices in its educational approach. Through an ethnographic approach that focuses on two women's recent experiences with social and cultural expectations around marriage, we argue that their strategies serve the prevention sector in the following ways: (1) they put into question the perpetrator–victim binary and official government warning signs, which suggest that coercive practices around marriage inherently render the family as a site of violence, and young adults as lacking the power to navigate these familial relationships; and (2) they reveal that young adult immigrant women see pressures around marriage through the prisms of collective care, sociality and the potential transformation and strengthening of familial bonds despite past experiences of social pressure.
Integrated miRNA and mRNA expression profiling reveals dysregulated miRNA‐mRNA regulatory networks in eosinophilic and non‐eosinophilic chronic rhinosinusitis with nasal polyps
Authors: Bu Xiangting , Wang Ming , Luan Ge , Wang Yang , Wang Chengshuo , Zhang Luo 
Published: February 2021

BackgroundThe precise mechanisms underlying pathogenesis of different subtypes of chronic rhinosinusitis with nasal polyps (CRSwNP) are still unclear. Emerging evidence indicates that microRNAs may play a role in the pathogenesis of CRSwNP. This study aimed to identify the dysregulated microRNA‒messenger RNA (miRNA‐mRNA) regulatory networks in eosinophilic (E) and non‐eosinophilic (non‐E) CRSwNP.MethodsWhole‐transcriptome sequencing was performed on nasal tissues of patients with ECRSwNP and non‐ECRSwNP, and control subjects. An integrated analysis of miRNA and mRNA expression was conducted to identify key mRNAs and miRNAs involved in the pathogenesis of ECRSwNP and non‐ECRSwNP. The miRNAs of interest and their target genes were validated using quantitative real‐time polymerase chain reaction (PCR).ResultsA group of differentially expressed mRNAs (DE‐mRNAs) and miRNAs (DE‐miRs) were identified in ECRSwNP patients vs control subjects, non‐ECRSwNP patients vs control subjects, and non‐ECRSwNP vs ECRSwNP patients, respectively. Pathway enrichment analysis showed distinct immune and inflammatory functions associated with DE‐mRNAs and target genes of DE‐miRs in ECRSwNP vs control and non‐ECRSwNP vs control groups. The miRNA‐mRNA regulatory networks constructed with Cytoscape highlighted the roles of miR‐154, miR‐221, and miR‐223 family miRNAs relating to both ECRSwNP and non‐ECRSwNP, and the roles of the let‐7 and miR‐34/449 families in the development of non‐ECRSwNP. Assessment using real‐time PCR for the expression of miRNAs and target genes demonstrated highly consistent data with the RNA sequencing data.ConclusionECRSwNP and non‐ECRSwNP patients express distinct miRNA‐mRNA regulatory networks compared with control subjects, thus providing potential targets for future development of novel therapeutic approaches for the management of CRSwNP.
Preparation of polyvinylpyrrolidone/graphene oxide/epoxy resin composite coatings and the study on their anticorrosion performance
Authors: Zhang Jian , Liu Zhongyuan , Zhang Lanhe , Ma Jun , Sun Dong , Zhang Di , Liu Jingrong , Bai Haina , Wang Bing 
Published: February 2021

AbstractWaterborne epoxy resin (EP) is often used as anticorrosive coating in the industrial field. However, small holes and gaps can be formed during the curing process. The corrosive medium easily penetrates the anticorrosive coating and corrodes the metal matrix. Herein, polyvinylpyrrolidone (PVP) and graphene oxide (GO) were doped into EP to improve the shielding and resistance to corrosive media. The composite coatings were prepared successfully by solution blending method. In the PVP/GO composite materials, original spatial structure of GO was changed and the composite was mainly combined by covalent bonding. The surface morphology of hybrid filler was flat and uniform, and the structural defects of GO was reduced. Compared with single‐layer anticorrosive coating, the corrosion potential of PVP/GO/EP coating moved forward and the corrosion current density decreased. The ideal corrosion resistance of PVP/GO/EP composite coatings was mainly because agglomeration of GO sheet was obviously avoided after it was modified by PVP. Furthermore, the hybrid filler can be uniformly dispersed in the aqueous EP. It blocked the gaps and holes inside the coatings, which could contribute to form anticorrosive coatings.
Fabrication of basalt embedded composite fiber membrane using electrospinning method and response surface methodology
Authors: Saleh Mohammed , Demir Didem , Ozay Yasin , Yalvac Mutlu , Bolgen Nimet , Dizge Nadir 
Published: February 2021

AbstractIn this study, a novel basalt embedded fiber membranes was prepared by the electrospinning method. The effects of the feed rate, voltage, tip to collector distance, and the basalt content on the prepared composite fiber membranes were investigated and optimized using the response surface method. Four models were built to compare the fibers in terms of deionized water flux (DWF), activated sludge flux, chemical oxygen demand (COD) removal, and porosity of fiber membranes. All the developed models were significant and adequately precise. The maximum flux of DWF was obtained when the voltage was 17.25 kV, the tip to collector distance of 19 cm, and a basalt content in polymer of 1.25%. COD removal decreased at higher voltage values as the feed rate increased. The porosity, pore size, and the contact angle values decreased for basalt embedded fiber membrane. The increases in the basalt percentage in polymer increased the hydrophilicity of the fiber. The flux decline for the basalt embedded fiber membrane was compared with the pristine fiber membrane. The permeate fluxes of pristine and basalt embedded fiber membranes were 42.3 and 59.6 L/m2/h, respectively. The biofouling performances of pristine and basalt embedded fiber membranes were also examined. Irreversible fouling decreased from 42.9% to 8.0%, and reversible fouling increased from 56.5% to 91.1% after modification of the membrane with basalt powder. Scanning electron microscopy with energy dispersive X‐ray analysis (SEM–EDX) analysis showed that basalt powder was successfully embedded into polyether sulfone polymer.
Structural and free volume characterization of sol–gel organic–inorganic hybrids, obtained by co‐condensation of two ureasilicate stoichiometric precursors
Authors: Kavetskyy Taras , Boev Victor , Ilcheva Vania , Kukhazh Yuliia , Smutok Oleh , Pan'kiv Lyudmyla , Šauša Ondrej , Švajdlenková Helena , Tatchev Dragomir , Avdeev Georgi , Gericke Eike , Hoell Armin , Rostamnia Sadegh , Petkova Tamara 
Published: February 2021

AbstractIn this study two hybrid organic–inorganic ureasilicate monomers with different length of polymer segments were chosen for preparation of sol–gel material that includes two moieties blended on the molecular scale. The first monomer was obtained by crosslinking a double terminated polyoxyalkyleneamine with an isocyanate modified silicone ethoxide and the second one – by crosslinking between the isocyanate modified silicone ethoxide with an amino modified silicone ethoxide. Sol–gel route was applied for transformation of the liquid monomer blends in transparent materials with varying degree of rigidity. The prepared samples were characterized by small‐angle X‐ray scattering, Fourier‐transform infrared spectroscopy, positron annihilation lifetime spectroscopy, and swelling experiments. The results demonstrate that the structure of the obtained materials could be tuned by a simple variation of molar fraction ratio between these two monomers. This makes it possible to obtain nanostructured materials with predictable properties.