bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural and magnetic properties analysis of trivalent Al3+ ions substituted Ni-Zn-Co nano-spinel ferrites
Authors: Jahan Nusrat , Khandaker J I , Das H , Khan M N I 
Published: November 2021

Abstract
This study explored the structural, morphological, optical, and magnetic properties of Ni0.4Zn0.35Co0.25Fe2−x
Al
x
O4 (0 ≤ x ≤ 0.12) nano-spinel ferrites. Nanocrystalline cubic structure formation and weight loss percentage were determined by thermogravimetric analysis and differential scanning calorimetry (TGA - DSC). Single-phase cubic spinel structures with Fd3m space group of synthesized samples were confirmed by Rietveld refinement X-ray diffraction (XRD) data. The particle sizes were found to be in the range of 6.7 nm–5.25 nm, and agglomeration occurs inside the ferrite samples. The atomic planes and strong crystallinity were detected through SAED images. The characteristic peaks of the Raman spectra identified the bonding between the cations and anions in the sub-lattices. The optical bandgaps (E

g
) were found to be in the range of 2.1 eV–2.52 eV. S-shape hysteresis (M-H) loops identified the superparamagnetic nature of the nano-samples. The studies’ outcomes indicated the applicability for biomedical applications of these nano samples.
Two-terminal vertical thyristor using Schottky contact emitter to improve thermal instability
Authors: Kim Min-Won , Kim Ji-Hun , Park Jun-Seong , Lee Byoung-Seok , Yoo Sang-Dong , Shim Tae-Hun , Park Jea-Gun 
Published: November 2021

Abstract
In a two-terminal-electrode vertical thyristor, the latch-up and latch-down voltages are decreased when the memory operation temperature of the memory cells increases, resulting in a severe reliability issue (i.e. thermal instability). This study fundamentally solves the thermal instability of a vertical-thyristor by achieving a cross-point memory-cell array using a vertical-thyristor with a structure of vertical n++-emitter, p+-base, n+-base, and p++-emitter. The vertical-thyristor using a Schottky contact metal emitter instead of an n++-Si emitter significantly improves the thermal stability between 293 K and 373 K. Particularly, the improvement degree of the thermal stability is increased significantly with the use of the Schottky contact metal work function. Because the thermal instability (i.e. degree of latch-up voltage decrement vs. memory operation temperature) decreases with an increase in the Schottky contact metal work function, the dependency of the forward current density between the Schottky contact metal and p+-Si based on the memory operation temperature reduces with increase in the Schottky contact metal work function. Consequently, a higher Schottky contact metal work function produces a higher degree of improvement in the thermal stability, i.e. W (4.50 eV), Ti (4.33 eV), Ta (4.25 eV), and Al (4.12 eV). Further research on the fabrication process of a Schottky contact metal emitter vertical-thyristor is essential for the fabrication of a 3D cross-point memory-cell.
Occupational Asthma: The Knowledge Needs for a Better Management
Authors: Rui Francesca , Otelea Marina Ruxandra , Fell Anne Kristin Møller , Stoleski Sasho , Mijakoski Dragan , Holm Mathias , Schlünssen Vivi , Larese Filon Francesca 
Published: November 2021

AbstractThe management of occupational asthma (OA) may be influenced by several factors and removal from exposure is the main tertiary prevention approach, but it is not always feasible without personal and socioeconomic consequences. Reducing the delay between the onset of suggestive symptoms of OA and the diagnosis of OA is associated with a better prognosis. Workers’ education to increase awareness to trigger agents and a medical surveillance program directed especially at at-risk workers could be helpful in reducing this latency time. An early identification of workers who develop rhinitis and conjunctivitis which often precede the onset of asthma symptoms could be important for an early identification of OA. This is particularly important for cases of asthma caused by high-molecular-weight sensitizers and in the early years of employment. The availability of financial support and compensation measures for workers with OA may influence the latency time before diagnosis and, consequently, may influence the OA outcomes. In conclusion, there is a need for high-quality cohort studies that will increase knowledge about risk factor that may influence the timing of diagnosis of OA. This knowledge will be useful for implementation of future surveillance and screening programs in workplaces.
Deciphering the oxylipin signatures of necrotrophic infection in plants. A commentary on: Differential modulation of the lipoxygenase cascade during typical and latentPectobacterium atrosepticuminfections
Authors: Wasternack Claus 
Published: November 2021

This article comments on:Vladimir Y. Gorshkov, Yana Y. Toporkova, Ivan D. Tsers, Elena O. Smirnova, Anna V. Ogorodnikova, Natalia E. Gogoleva, Olga I. Parfirova, Olga E. Petrova, and Yuri V. Gogolev, Differential modulation of the lipoxygenase cascade during typical and latent Pectobacterium atrosepticum infections, Annals of Botany, Volume 129, Issue 3, 16 Februray 2022, Pages 271–285 https://doi.org/10.1093/aob/mcab108
Role of copper nanoparticles in wound healing for chronic wounds: literature review
Authors: Salvo Jessica , Sandoval Cristian 
Published: November 2021

Abstract
Chronic wounds are defined as wounds that fail to proceed through the normal phases of wound healing in an orderly and timely manner. The most common and inevitable impairment to wound healing is the installation of an infection, usually in the case of chronic wounds. Therefore, the objective of the present review was to identify the importance of copper nanoparticles in dressings for wound healing. Nanoparticles such as silver, gold and copper combat infectious processes through the inhibition of protein synthesis, peroxidation of the cell membrane and destroying the nucleic acids of bacteria and viruses. Among bioactive nanoparticles, copper plays a complex role in various cells, it modulates several cytokines and growth factor mechanisms of action and is essentially involved in all stages of the wound healing process. More importantly, copper plays a key role in skin regeneration and angiogenesis and accelerates the healing process through induction of vascular endothelial growth factor (VEGF) and angiogenesis by hypoxia-induced factor-1-alpha (HIF-1α) action where copper enhances HIF-1α expression and HIF-1α binding to the critical motifs in the promoter and putative enhancer regions of HIF-1-regulated genes.
Changing trends in presentation and indications of biopsy in lupus nephritis: data from the Spanish Registry of Glomerulonephritis
Authors: Shabaka Amir , Landaluce-Triska Eugenia , Sánchez-Álvarez José Emilio , Fernández-Juárez Gema 
Published: November 2021

ABSTRACT

Background
With the ageing population and changes in the indications of diagnostic and protocol biopsies in systemic lupus erythematosus in recent years, an impact on the incidence and presentation of lupus nephritis (LN) is expected. The aim of this study was to analyse the epidemiological changes regarding clinical and histological presentation of LN in kidney biopsies performed from 1994 to 2019 included in the Spanish Registry of Glomerulonephritis.

Methods
We analysed data from 28 791 kidney biopsies from 130 Spanish hospitals comparing demographic, clinical and histological data. We divided the cohort according to the age of onset of LN into pediatric onset (&lt;18 years), adult onset (18–50 years) and late onset (&gt;50 years).

Results
The incidence of LN has decreased from 9.6% of all kidney biopsies in the period 1994–2013 to 7% in the last quarter of the observation period (2014–2019) (P &lt; 0.001), despite an increase in the proportion of patients with LN that underwent repeat biopsies (16.6–24%; P &lt; 0.001). The age of onset of LN has increased from 32 ± 14 to 38 ± 14 years (P &lt; 0.001), with an increase in the proportion of late-onset LN (from 13% to 22% of incident LN; P &lt; 0.001). There were no differences in the distribution of histological features at presentation over the study period. Patients with late-onset LN showed fewer gender differences, had lower GFR and presented with less-proliferative forms of LN compared with early-onset LN.

Conclusions
The frequency of biopsy-proven LN has been decreasing in recent years, despite an increasing number of repeat biopsies. Late-onset LN is increasing, presenting with worse kidney function but fewer proliferative lesions compared with younger-onset LN.
Gut biofilms:Bacteroidesas model symbionts to study biofilm formation by intestinal anaerobes
Authors: Béchon Nathalie , Ghigo Jean-Marc 
Published: November 2021

ABSTRACTBacterial biofilms are communities of adhering bacteria that express distinct properties compared to their free-living counterparts, including increased antibiotic tolerance and original metabolic capabilities. Despite the potential impact of the biofilm lifestyle on the stability and function of the dense community of micro-organisms constituting the mammalian gut microbiota, the overwhelming majority of studies performed on biofilm formation by gut bacteria focused either on minor and often aerobic members of the community or on pathogenic bacteria. In this review, we discuss the reported evidence for biofilm-like structures formed by gut bacteria, the importance of considering the anaerobic nature of gut biofilms and we present the most recent advances on biofilm formation by Bacteroides, one of the most abundant genera of the human gut microbiota. Bacteroides species can be found attached to food particles and colonizing the mucus layer and we propose that Bacteroides symbionts are relevant models to probe the physiology of gut microbiota biofilms.
Antibiotic use and resistance in a tertiary care hospital: knowledge and attitude among patients of orthopaedic and surgical wards in Malaysia
Authors: Pauzi Zulsairi Mohd , Hassan Bassam Abdul Rasool , Neo Chin Fen , Mohammed Ali Haider , Blebil Ali , Dujaili Juman 
Published: November 2021

Abstract

Objectives
The prevalence of antimicrobial resistance (AMR) is rising globally as well as in Malaysia. AMR can lead to difficulty in the treatment of chronic infection if being neglected. This study aimed to assess the level of knowledge and attitude about antibiotic usage and AMR.

Methods
A cross-sectional study design was carried out at the Hospital Kuala Lumpur (HKL), Malaysia, where participants were recruited by using the non-probability convenience sampling from the six orthopaedic and four surgical wards. A self-administered questionnaire was used to collect the required data which were then analysed by using SPSS.

Key findings
A total number of 390 adult Malaysians (286 from orthopaedic wards and 104 from surgical wards) were involved in the study. This study showed that the level of knowledge and attitude about antibiotics among the majority of respondents were moderate. However, their knowledge regarding AMR was very low (i.e. lack of knowledge). In contrast, the majority of them (69.8%) showed a positive attitude towards antibiotics. Statistical analysis of data revealed that the level of knowledge of AMR was significantly associated with gender, age, race, marital status, educational level and knowledge about antibiotic resistance terms (P &lt; 0.05) while respondents’ attitude towards antibiotic usage was significantly associated with gender, race, marital status and education level (P &lt; 0.05).

Conclusions
It was necessary to formulate and develop strategies to improve the knowledge and awareness about antibiotics and AMR among health professionals. These might help them to improve their skills in delivering health information to the patients through a proper counselling technique.
Case C-848/19 P: Germany v Poland and its outcomes for EU energy sector: an extended case note on the European Court of Justice judgment in the OPAL case
Authors: Iakovenko Mykola 
Published: November 2021

Abstract
The European Court of Justice (ECJ) judgment in the so-called Ostsee-Pipeline-Anbindungsleitung (OPAL) case on 15 July 2021 dismissed Germany’s appeal on the previous European Union (EU) General Court’s decision, which focused on the need for considering national interests of EU Member States and the interests of the Union itself in the decisions by the EU institutions in energy sector to acknowledge the solidarity principle provided in the Treaty on the Functioning of the European Union. This decision found a significant interest among academicians and legal practitioners and raised numerous discussions, since it is still not clear what are the exact criteria on application of this principle, especially in relation to such ambiguous energy notions as ‘security of supply’. The presence of the geopolitical context and direct impact of the decision on the volumes of Russian gas transported via the Nord Stream pipeline also makes this case extremely complex and raises some additional questions regarding the impact on external gas supply to the EU. Moreover, the statement of the Advocate General on the applicability of the solidarity principle to all the other objectives of EU energy policy (not limiting to the scope of security of gas supply), which was also supported by the Court, brings many additional aspects to be considered with regards to the impact of the OPAL case on EU energy sector. Therefore, this case note article undertakes a critical analysis of the recent ECJ judgment and Advocate General’s opinion to identify some gaps that are still not clarified and to estimate the possible outcomes of the judgment on the future of EU energy sector development.
Countably many sublogics of the interpretability logicILhaving fixed point properties
Authors: Okawa Yuya 
Published: November 2021

AbstractWe investigate the fixed point properties for sublogics of the interpretability logic $\textbf {IL}$. In our previous work, it was proved that a sublogic $\textbf {IL}^{-}(\textbf {J 2}_+, \textbf {J 5})$ has the fixed point property (FPP) and that a sublogic $\textbf {IL}^{-}(\textbf {J 4}, \textbf {J 5})$ has a newly introduced weaker property $\ell $FPP. In this paper, we provide countably many sublogics of $\textbf {IL}^{-}(\textbf {J 2}_{+}, \textbf {J 5})$ (resp. $\textbf {IL}^{-}(\textbf {J 4}, \textbf {J 5})$) having FPP (resp. $\ell $FPP).
Diet high in branched-chain amino acid promotes PDAC development by USP1-mediated BCAT2 stabilization
Authors: Li Jin-Tao , Li Kai-Yue , Su Ying , Shen Yuan , Lei Ming-Zhu , Zhang Fan , Yin Miao , Chen Zheng-Jun , Wen Wen-Yu , Hu Wei-Guo , Su Dan , Qu Jia , Lei Qun-Ying 
Published: November 2021

Abstract
BCAT2-mediated branched-chain amino acid (BCAA) catabolism is critical for pancreatic ductal adenocarcinoma (PDAC) development, especially at an early stage. However, whether a high-BCAA diet promotes PDAC development in vivo, and the underlying mechanism of BCAT2 upregulation, remain undefined. Here, we find that a high-BCAA diet promotes pancreatic intraepithelial neoplasia (PanIN) progression in LSL-KrasG12D/+; Pdx1-Cre (KC) mice. Moreover, we screened with an available deubiquitylase library which contains 31 members of USP family and identified that USP1 deubiquitylates BCAT2 at the K229 site. Furthermore, BCAA increases USP1 protein at the translational level via the GCN2-eIF2α pathway both in vitro and in vivo. More importantly, USP1 inhibition recedes cell proliferation and clone formation in PDAC cells and attenuates pancreas tumor growth in an orthotopic transplanted mice model. Consistently, a positive correlation between USP1 and BCAT2 is found in KC; LSL-KrasG12D/+; p53flox/+; Pdx1-Cre mice and clinical samples. Thus, a therapeutic targeting USP1-BCAT2-BCAA metabolic axis could be considered as a rational strategy for treatment of PDAC and precisive dietary intervention of BCAA has potentially translational significance.
HSC-XXL: Baryon budget of the 136 XXL groups and clusters
Authors: Akino Daichi , Eckert Dominique , Okabe Nobuhiro , Sereno Mauro , Umetsu Keiichi , Oguri Masamune , Gastaldello Fabio , Chiu I-Non , Ettori Stefano , Evrard August E , Farahi Arya , Maughan Ben , Pierre Marguerite , Ricci Marina , Valtchanov Ivan , McCarthy Ian , McGee Sean , Miyazaki Satoshi , Nishizawa Atsushi J , Tanaka Masayuki 
Published: November 2021

AbstractWe present our determination of the baryon budget for an X-ray-selected XXL sample of 136 galaxy groups and clusters spanning nearly two orders of magnitude in mass (M500 ∼ 1013–1015 M⊙) and the redshift range 0 ≲ z ≲ 1. Our joint analysis is based on the combination of Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP) weak-lensing mass measurements, XXL X-ray gas mass measurements, and HSC and Sloan Digital Sky Survey multiband photometry. We carry out a Bayesian analysis of multivariate mass-scaling relations of gas mass, galaxy stellar mass, stellar mass of brightest cluster galaxies (BCGs), and soft-band X-ray luminosity, by taking into account the intrinsic covariance between cluster properties, selection effect, weak-lensing mass calibration, and observational error covariance matrix. The mass-dependent slope of the gas mass–total mass (M500) relation is found to be $1.29_{-0.10}^{+0.16}$, which is steeper than the self-similar prediction of unity, whereas the slope of the stellar mass–total mass relation is shallower than unity; $0.85_{-0.09}^{+0.12}$. The BCG stellar mass weakly depends on cluster mass with a slope of $0.49_{-0.10}^{+0.11}$. The baryon, gas mass, and stellar mass fractions as a function of M500 agree with the results from numerical simulations and previous observations. We successfully constrain the full intrinsic covariance of the baryonic contents. The BCG stellar mass shows the larger intrinsic scatter at a given halo total mass, followed in order by stellar mass and gas mass. We find a significant positive intrinsic correlation coefficient between total (and satellite) stellar mass and BCG stellar mass and no evidence for intrinsic correlation between gas mass and stellar mass. All the baryonic components show no redshift evolution.
New avenues for functional neuroimaging: ultra-high field MRI and OPM-MEG
Authors: Qin Lang , Gao Jia-Hong 
Published: November 2021

Abstract
Functional brain imaging technology has developed rapidly in recent years. On the one hand, high-field 7-Tesla magnetic resonance imaging (MRI) has excelled the limited spatial resolution of 3-Tesla MRI, allowing us to enter a new world of mesoscopic imaging from the macroscopic imaging of human brain functions. On the other hand, novel optical pumping magnetometer-magnetoencephalography (OPM-MEG) has broken down the technical barriers of traditional superconducting MEG, which brings imaging of neuronal electromagnetic signals from cortical imaging to whole-brain imaging. This article aims to present a brief introduction regarding the development of conventional MRI and MEG technology, and, more importantly, to delineate that high-field MRI and OPM-MEG complement each other and together will lead us into a new era of functional brain imaging.
Noninvasive brain stimulation of addiction: one target for all?
Authors: Liu Qingming , Yuan Tifei 
Published: November 2021

Abstract
Noninvasive brain stimulation includes repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), and emerges as a prospective approach for addiction treatment in clinical practices. The dorsolateral prefrontal cortex (DLPFC) is regarded as the most effective stimulation target, giving its important position in controlling cue-elicited drug craving and initiating drug abuse. In this paper, through literature searches (e.g. Pubmed, Google Scholar), 34 studies (2003–2021) were identified examining the effect of rTMS, tDCS on cravings, and consumption of substance use disorders, including tobacco, alcohol, opioids, and stimulants. We summarize the main methods, designs, and effects of rTMS or tDCS that are delivered to the DLPFC on different types of addiction. We conclude that targeting DLPFC might be effective for all types of drug addiction.
Arginine: What You Need to Know for Pressure Injury Healing
Authors: Chu Andy S. , Delmore Barbara 
Published: November 2021

GENERAL PURPOSE
To provide information about arginine, its metabolism, and its role in acute and chronic wound healing, to assist providers in understanding the recommendations for arginine supplementation.

TARGET AUDIENCE
This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care.

LEARNING OBJECTIVES/OUTCOMES
After participating in this educational activity, the participant will:
1. Describe the characteristics of arginine.
2. Choose the metabolic processes that define arginine’s role in wound healing.
3. Identify the average daily intake of arginine in an American diet.
4. Select the evidence that demonstrates the effectiveness of arginine supplementation for wound healing.

ABSTRACT
Nutrition has an important and integral role in wound healing. Arginine, a type of indispensable amino acid, has long been thought to have wound healing properties. The 2019 international guideline by the European Pressure Ulcer Advisory Panel, National Pressure Injury Advisory Panel, and Pan Pacific Pressure Injury Alliance recommends use of a high-protein, high-calorie oral nutrition supplement fortified with arginine and other antioxidants to treat adults with stage 2 or greater pressure injury and who are malnourished or at risk of malnutrition to foster healing. This article provides necessary background on this conditionally indispensable amino acid, its metabolism, and its role in acute and chronic wound healing to assist providers in understanding the recommendation for arginine supplementation.
Non-scarring Minimal Incision Neo-omphaloplasty in Abdominoplasty: The Alvarez Technique. A New Proposal
Authors: Alvarez Edwar , Alvarez David , Caldeira Alberto 
Published: November 2021

Background:
Abdominoplasties are increasingly requested aesthetic, reconstructive surgical procedures that, in most cases, have shown the disadvantage of leaving an often-notorious periumbilical scar due to hypertrophy, keloid, or because it simply remains very visible over time, after surgery. The Alvarez technique (or nonscarring minimal-incision neo-omphaloplasty) is a completely new, unprecedented technique because it does not leave visible scars. This technique requires the generation of four small flaps and a purse-string suture system interacting with the aponeurosis of the rectus abdominis muscles, as well as the modification of the vertical abdominal plication, and management of the subcutaneous cellular tissue in the new umbilicus area, which, if executed correctly, provide adequate aesthetic results.

Methods:
A multicentric case-series scientific study is presented with a total of 94 patients who underwent classical abdominoplasties and neo-omphaloplasties with the aforementioned technique from August 2018 to December 2020. Pre-surgical and postoperative photographic files were collected.

Results:
Of the 94 patients, there were eight (8.5%) cases of seroma, which are not attributable to neo-omphaloplasty but inherent to the use of drains. There were five (5.3%) cases of umbilical dehiscence. In total, 89.2% (84 patients) showed a very high degree of long-term satisfaction, and 10.6% (10 patients) had a medium level of long-term satisfaction.

Conclusions:
The Alvarez technique provides good aesthetic results that are well accepted among patients and surgeons, in the short and long term. It is useful for those patients who wish to undergo an abdominoplasty but cannot stand a scar in the umbilical region.