bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dual-energy Computed Tomography for the Diagnosis of Acute Gouty Arthritis
Authors: Huang Zengfa , Li Zuoqin , Xiao Jianwei , Xie Yuanliang , Hu Yun , Zhang Shutong , Wang Xiang 
Published: July 2021

Aims:
To investigate the diagnostic value of dual-energy computed tomography (DECT)
in Acute Gouty Arthritis (AGA) or patients presenting suspected gouty arthritis.

Methods:
This retrospective study was performed in a single centre from May 2017 to August
2018. Two hundred and twenty-six patients with an initial diagnosis of AGA in the preceding 15
days were included. All patients were referred for a DECT scan of the affected joints. The diagnosis
criteria of gout with the American College of Rheumatology Classification Standard were regarded
as the reference standard.

Results:
After filtration, two hundred patients were included in the present study. The sensitivity,
specificity, positive predictive value, and negative predictive value of DECT in the diagnosis of all
AGA were 83.83%, 60.61%, 91.5%, and 42.55%, respectively. When AGA was subdivided according
to the joint site, the sensitivity, specificity, positive predictive value, and negative predictive
value were 80.68%, 61.11%, 91.03%, and 39.29% in feet, 93.55%, 40%, 93.55%, and 40% in
knees and 87.5%, 71.43%, 91.3%, and 62.5% in ankles, respectively.

Conclusions:
DECT had a high sensitivity for the diagnosis of AGA. However, the specificity was
limited, particularly for the diagnosis of acute gouty knee arthritis. Prospective multicenter studies
of large samples will enhance the application of DECT among AGA patients in the future.
The Evaluation of the Maculopathy Using Dynamic Contrast-enhanced MRI in Patients with Proliferative Diabetic Retinopathy
Authors: Chen Zhiye , Xu Huan , Liu Mengqi , Li Chunfang , Huang Houbin , Ma Lin 
Published: July 2021

Background:
Dynamic Contrast-enhanced Magnetic Resonance Imaging (DCE-MRI)
technique could not only quantify blood-retinal barrier (BRB) breakdown leading to macular edema
associated with diabetes, but also provide a two-dimensional imaging method that is not interfered
by refracting media.

Objective:
The current study was aimed to evaluate the macular change in the patients with diabetic
retinopathy using DCE-MRI technique.

Methods:
Twenty patients with Diabetic Retinopathy (DR) and 20 Normal Controls (NC) were included.
The fast spoiled gradient echo sequence was used to perform dynamic contrast T1WI enhancement
on 3.0T MR system. The macular region, optic papila and nasal retina were performed
with quantitative DCE-MRI evaluation using Omni-Kinetics software.

Results:
The maximal concentration, the area under the concentration-time curve (AUCconcentration-time)
and maximal slope of macular region were significantly higher in DR [0.270(0.03,1.20)mmol/
100ml, 2.71(0.04,9.91) mmol*min and 0.38(0.06,3.18) mmol/min, respectively] than that
[0.169(0.03,0.72) mmol/1.25(0.13,10.41) mmol*min and 0.245(0.06,1.34) mmol/min] in NC (U
value = 515.00 and P value = 0.080, U value = 433.00 and P value = 0.000, and U value = 563.00
and P value = 0.023, respectively). The receiver operating characteristic curve (ROC) analysis demonstrated
that the area under AUCconcentration-time was 0.729±0.058 with the cut-off value 1.479
mmol*min (sensitivity 80.00% and specificity 62.50%) for macular region.

Conclusion:
The quantitative DCE-MRI technique could be used to evaluate the maculopathy associated
with diabetic retinopathy.
Ethnobotanical Study of Medicinal Plants Used for Management of Cancer in Karonga District, Northern Malawi
Authors: Tembo David , Mwamatope Bonface , Chikowe Ibrahim , Maliwichi-Nyirenda Cecilia , Kampira Elizabeth , Masumbu Friday Foster 
Published: July 2021

Background:
In Malawi, cancer is one of the leading causes of morbidity and mortality. This has led to
increased use of herbal medicines for cancer management.

Objective:
This study aimed at identifying medicinal plants that are used for the management of cancer in the southern
area of Karonga district, Northern Malawi.

Methods:
Semi-structured individual questionnaire interviews were used to collect ethnobotanical data from traditional
herbal practitioners in the study area.

Results:
A total of twenty six (26) plant species from seventeen (17) botanical families were reported by Traditional
Herbal Practitioners to be effective in the management of cancer. The botanical families with representation of more
than one plant species were Fabaceae with five species, followed by Combretaceae and the Anacardiaceae with three
species each, and Meliaceaewith with two species. The relative frequency of citation (RFC) showed that Senna singueana
(RFC = 0.833), Lannea discolour (RFC = 0.833), Melia azedarach (RFC = 0.667), and Moringa oleifera (RFC
= 0.667) were the medicinal plant species which were frequently mentioned and used in the study. The recipes could be
a mixture of plant species or plant parts such as the leaves, barks, roots, rhizomes, seeds, flowers, and fruits.

Conclusion:
The study showed that a potential cancer management drug could be developed from the medicinal plant
species found in the area. The results of this study could provide baseline information on medicinal plant species for
further phytochemical studies and other studies to validate their use.
Accurate Assessment of Joule-Thomson Inversion Temperature at Zero Pressure of Imperfect Gases
Authors: Mamedov Bahtiyar Akber , Somuncu Elif 
Published: July 2021

Background:
The aim of this work is to propose an approach for estimating the
Joule-Thomson coefficient as an important parameter necessary to the study of changes in
fluid temperature at a given change in pressure at constant enthalpy.

Objective:
The analytical approach presented in this work is very appropriate for detailed
studies of the Joule-Thomson inversion temperature at zero pressure for arbitrary temperature
values.

Methods:
A new approach is suggested for the accurate determination of the Joule-
Thomson inversion temperature at zero pressure using virial coefficient of the Lennard-
Jones (12-6) potential.

Results:
The usefulness and efficiency of the method are tested by application to various
gases Ar, He, Ne, H2, O2, CO2 CO, CH4, Xe, Kr, N2 and Air. The results obtained are in
well agreement with other approximation and experimental data.

Conclusion:
The suggested formula enables correct and rapid calculation of the JT inversion
temperature at zero pressure.
Association Between miR-146a rs2910164 Polymorphism and Breast Cancer
Susceptibility: An Updated Meta-Analysis of 9545 Cases and 10030
Controls
Authors: Moazeni-Roodi Abdolkarim , Aftabi Sajjad , Sarabandi Sahel , Karami Shima , Hashemi Mohammad , Ghavami Saeid , Taheri Mohsen 
Published: July 2021

Background:
Several studies have reported a possible association of miR-146a
rs2910164 polymorphism with Breast Cancer (BC) development. However, the correlation between
this polymorphism and susceptibility to BC is under debate. The current meta-analysis was
designed and performed to more conclusively evaluate the miR-146a rs2910164 polymorphism
and its potential link to BC.

Methods:
Our team has selected eligible studies (published up to October 2, 2020) from several
electronic databases, including Web of Science, PubMed, Scopus and Google Scholar. A total number
of 9,545 BC cases and 10,030 controls extracted from 26 eligible articles were included in this
study. We utilized pooled Odds Ratios (ORs) as well as 95% confidence intervals (95% CIs) under
five genetic models for quantitative estimation of any possible association between miR-146a
rs2910164 polymorphism and BC.

Results:
Based on this meta-analysis, our findings suggest that there is no significant association
between miR-146a rs2910164 polymorphism and BC risk. However, stratified analysis revealed
that the rs2910164 polymorphism significantly increased the risk of BC in hospital-based studies
using the homozygous genetic model (OR=1.37, 95%CI=1.01-1.86, p=0.043, CC vs. GG). Neither
Asian nor Caucasian populations showed any significant association between rs2910164 polymorphism
and BC susceptibility.

Conclusion:
In summary, our findings suggest that BC development is not associated with
miR-146a rs2910164 polymorphism. However, larger ingenious future investigations might be
needed for a more precise estimation of any association between miR-146a rs2910164 polymorphism
and BC.
Farmers’ Willingness To Pay For Livestock Insurance Programs In Kulon Progo District
Authors: Kurniaty Tri , Masyhuri Masyhuri , Jamhari Jamhari 
Published: July 2021

Livestock Insurance is one of the insurance products supported by the government with PT Jasindo as the organizer. Livestock insurance will provide the potential for cattle ranchers who can get risk threats such as cattle deaths due to illness, accidents, losses caused by theft, and deaths due to breeding. This study aims to determine the value of the willingness of farmers to pay the insurance and the factors that affect the willingness of farmers to pay insurance. This research was conducted from February to March 2020 in the Kulon Progo district. Location determination is done by purposive sampling based on data from the farmer following the insurance program. Primary data obtained from 53 farmers with the help of a questionnaire and analyzed by the method of contingency value (CVM) and multiple linear regression. The research shows the average value of willingness to pay insurance is IDR45,660 per head per year above the value of the insurance premium assessment. Factors that significantly influence a Farmer's Willingness to Pay (WTP) for the Insurance program are the variable number of family dependants and income, while the age, duration of raising, and education have no significant effect. Based on the value of the EWTP obtained, which is very low, the expectation of farmers is not to demand too low a price.
IMPACT OF CHRONIC NOISE ON HIPPOCAMPAL MORPHOLOGY AND ITS FUNCTIONS IN WISTAR ALBINO RATS
Authors: ARJUNAN ARCHANA , RAJAN RAVINDRAN 
Published: July 2021

Objective: The study aims to investigate the effect of chronic noise stress on hippocampal morphology and its functions in male Wistar albino rats.
Methods: Adult albino rats were randomly divided into two groups. Each group contained six animals. Rats exposed to chronic noise stress (100 dB/4 h–30 days) were compared with control animal and assessed for behavior using hole-board test, marble burying test, and morphology of hippocampus by histology.
Results: The rats exposed to chronic noise stress showed significance (P < 0.05) of behavioral alterations such as increased fear and anxiety, obsessive-compulsive behavior, enlarged lateral ventricle, and reduced hippocampal volume.
Conclusion: The results reported that chronic noise stress affects neurobehavioral due to reduced hippocampal volume.
PLANTS OF GANDHAMARDAN IN MATERNAL CARE: AN ETHNOBOTANICAL APPROACH
Authors: DAS SONALIKA , MOHATY SULAGANA , NAYAK SHEETISWAPNA , BHATTA KALPITA 
Published: July 2021

Objective: The traditional use of plants in herbal medicine has paved the way for drug discovery. With a view of this, the present study was carried out in Gandhamardan hills which are a rich source of medicinal plants. However, there are copious reports about the plants used in maternal care. Therefore, an attempt has been made to record and document the plants of these hills utilized in maternal care.
Methods: The ethnobotanical information on applications of different plant species to cure diseases and ailments of pregnancy, birth (parturition), and postpartum (puerperium) were documented through personal discussions, interviews with focused groups combined with field visits, voice recordings, and photo documentation.
Results: The study showed that 24 vascular plant species belonging to 24 genera and 22 families have been used in maternal care. Most of the species were herbs (50%) followed by trees (32.5%), climbers, and herbs (20%). It was observed that among all the parts, generally leaves were widely used.
Conclusion: This ethnobotanical study documented the use of plants among the local community. It also revealed that the medicinal plants of the hills are a cheap source of herbal drugs for the rural communities. The information gathered can be used for further scientific investigation to develop new plant-based commercial drugs as they will be safer than synthetic drugs.
EVALUATION OF SOME MINERALS AND VITAMINS IN CORD BLOOD FROM RURAL AND URBAN POPULATION OF UDAIPUR REGION
Authors: JAIN SUMAN , BANSAL PRERNA , PRAJAPAT RAJNEESH , JADEJA HARSHDEEP 
Published: July 2021

Objective: Vitamins and minerals collectively referred to as micronutrients have important influence on the health of pregnant women and the growing fetus. Pregnancy is related to increase demand of all nutrients and deficiency any of these can affect pregnancy, delivery, and outcome of pregnancy. Disorders in mineral element nutrition and metabolism can lead to wide variety of malformations. Data on mineral values in newborn are very less in contrast to adult. The present study was planned to analyze some of minerals in the umbilical cord blood of rural and urban population and compare them gender wise.
Methods: Our study group consisted of 640 healthy term newborn. The cord blood was collected immediately after a normal delivery. The blood was tested to determine calcium (Ca), magnesium (Mg), Phosphorus (P), Iron (Fe), Vitamins D3, and Vitamin B12.
Results: The results showed that the levels of Ca, Mg, P and Fe, Vitamin D3, and Vitamin B12 were higher in urban population than rural ones. All were statistically significant. The levels of Mg, P, Fe, and Vitamin B12 were lower in female urban neonates as compared to male urban neonates. All were significant when compared sex wise. The trend was same with increased levels of Mg, P, Fe, and Vitamin B12 in females of rural population than cord blood of male rural neonates.
Conclusions: The result showed that rural and urban population also female and male neonates have genetic variation and difference in mineral metabolism.
FABRICATION AND ASSESSMENT OF LERCANIDIPINE HYDROCHLORIDE SOLID DISPERSIONS FOR SOLUBILITY PREFERMENT USING POLYMER COMBINATION
Authors: REDDY NAZEMOON , DUGASANI SWARNALATHA , NAYAKANTI DEVANNA 
Published: July 2021

Objective: An attempt has made in fabricating solid dispersions (SDs) by taking lercanidipine hydrochloride (LCD) as a model drug.
Methods: The SDs were made using a poly mix of poly vinyl pyrrolidone (PVP) K-30, Poloxamer-188, and hydroxy propyl methyl cellulose (HPMC) K4M. Different proportions of LCD: polymer mix in 1:1, 1:3, 1:5, and 1:7 ratios were fabricated as SDs by solvent evaporation and melting method, further compressed into tablets. The LCD SDs were assessed for physicochemical, and LCD release possessions.
Results: The results were observed to be attractive with the increase in solubility LCD SD (F-3 and F-7) with 1:5 ratios of LCD.
Conclusion: The study concludes that the poly mix of PVP K-30, Poloxamer-188, and HPMC K4M and was found to be a better combination for elevating the solubility and release of LCD from the SDs.
FOOD: INVISIBLE BRIDGE CONNECTING THE PAST AND PRESENT DAY OF DIASPORIC IDENTITY
Authors: Hariyatmi Sri 
Published: July 2021

As people migrate, they move along with their emotional luggage including flavors, aromas, smells, and their gastronomical experience that also travel with them. This paper seeks to explore the role of food in the life of diaspora and how their negotiation to choose food in their new “home” has become a magical space that allows them to reconfigure their sensory system and eventually makes them a person with richer sensory systems. Several studies have been conducted to explore the relationship between personal identity and food preference. None, however, discusses how food choice influences the reconstruction of identity. Thus, this study aimed at filling the niche by exploring the relationship between food and its influence in reconstructing identity quest. This qualitative study collected its data from ten diasporas living in Thailand and Indonesia by using an informal semi-structured interview. The interview results were employed as the main data of this study. In addition, a descriptive qualitative technique was used to analyze the data. Drawing on Babha’s concept of hybridity, this paper argues that firstly, food is an invisible bridge connecting the past and present-day of diasporic identity. Secondly, it also served as the shrine of negotiation for the diaspora in this study to reconfigure their identity in enduring adversity from living under a new dominant culture.
Patency and Efficacy of Anatomical Snuffbox Arteriovenous Fistula Compared with Wrist Fistula in Patients with End-Stage Renal Disease
Authors: Nazari Iraj , Tajali Hossein , Majidi Saeedeh , Joudi Marjan , Pouya Farzaneh , Ghaderifar Shiva , Abbasi Zahra 
Published: July 2021

Highlights

Abstract
Introduction: Snuffbox arteriovenous fistula (AVF) is one of the most common vascular accesses for hemodialysis. Despite all the advantages, it is not usually considered the first choice of treatment. This could be primarily due to difficulty in its technical procedure and a higher probability of failure than other sites such as cubital. Therefore, the present study aimed at comparing the efficacy and patency rate between the snuffbox and the wrist AVF. Methods: Seventy-eight patients with end-stage renal disease were enrolled in this study. They were randomly assigned into the snuffbox and the wrist groups. Each participant had an appropriate vein at the time of examination and was eligible for distal AVF creation. The procedure was conducted under local anesthesia, and arteriovenous anastomosis was done in an end-to-side configuration. AVF maturation was defined by initiation of successful dialysis through the AVF 8–10 weeks postoperatively.
Results: The results showed that 61% of snuffbox AVFs and 65% of wrist AVFs became matured and were used for further dialysis. Diabetes and female sex had negative impacts on AVF patency. In addition, no significant relationship was found between the patency rate and demographic as well as clinical variables such as age, hypertension, and duration of the previous dialysis.
Conclusions: No significant differences were found in the maturation and patency rate between the wrist and the snuffbox AVFs. Therefore, the snuffbox fistula is recommended in the first step, as there would be a possibility for re-creation on the ipsilateral wrist once the AVF fails.
PEMENUHAN HAK PEKERJA ATAS KELEBIHAN WAKTU KERJA PADA SAYAN POINT RESTAURANT
Authors: Gina Anggreni Ni Made , Sarjana I Made 
Published: July 2021

Tujuan yang penulis ingin capai dalam jurnal ini adalah untuk mengkaji hak yang seharusnya diperoleh oleh pekerja yang melebihi batas waktu kerja dan mengkaji berbagai faktor yang menyebabkan sulitnya pemenuhan hak atas pekerja yang melebihi batas waktu kerja. Penelitian jurnal ini menggunakan metode penelitian hukum empiris yakni melakukan pengamatan terhadap suatu peraturan perundang–undangan yang ada terhadap pelaksanaan suatu aturan dalam masyarakat. Hasil penelitian pada Sayan Point Restaurant menunjukkan bahwa beberapa ketentuan terkait pemenuhan hak pekerja atas kelebihan waktu kerja belum terpenuhi penggunaan perintah tertulis, pemberian makan saat lembur. Faktor penghambat terhadap pelaksanaan pembayaran upah lembur yang tidak diberikan serta pemberian makan saat lembur yang lebih dari 3 jam, pemilik restoran dan pekerja kurang mengetahui mengenai adanya pengaturan tersebut.

The purpose of the author want to achieve in this journal is to examine the rights that should be obtained by workers who exceed the work time limit and examine various factors that make it difficult to fulfill the rights to workers who exceed the work time limit. This research journal uses an empirical method that is observing an existing legislation regarding the implementation of a rule in society. The results showed at Sayan Point Restaurant that several provisions related to the fulfillment of workers' rights to excess work time had not yet been met the use of written instructions, feeding on overtime. Obstacles to the implementation of payment of overtime wages that are not given as well as feeding overtime for more than 3 hours, restaurant owners and workers are less aware of the regulation.
PERTANGGUNGJAWABAN PIDANA TERHADAP KORPORASI SEBAGAI PELAKU TINDAK PIDANA DALAM UNDANG-UNDANG PEMBERANTASAN TINDAK PIDANA KORUPSI
Authors: Wardhani Ni Made Kusuma , Suartha Dewa Made 
Published: July 2021

Tujuan studi ini untuk mendeskripsi dan menganalisis pertanggungjawaban pidana korporasi serta penentuan korporasi sebagai pelaku tindak pidana korupsi berdasarkan UU PTPK. Studi ini menggunakan metode penelitian hukum normatif dengan menggunakan pendekatan perundang-undangan dan analisis konsep hukum. Hasil studi menunjukkan bahwa dalam pembebanan pertanggungjawaban pidana masih berlaku asas “green straf zonder schuld” dengan menggunakan doktrin identifikasi. Selanjutnya tidak semua pasal dalam UU PTPK berdasarkan Pasal 1 ayat (3) UU PTPK dapat dimintakan pertanggungjawaban pidana terhadap korporasi sehingga diperlukan penafsiran lebih lanjut.
The purpose of this study is to description and analyze corporate criminal liability as well as corporate determination as perpetrators of corruption crimes under the law on corruption eradication. This study uses normative legal research methods using statutory approaches and analysis of legal concepts. The results showed that in the loading of criminal liability still applies the principle of "green Straf zonder Schuld" Using the doctrine of identification. Furthermore, not all articles in the law on corruption eradication pursuant to article 1 paragraph (3) of the law on corruption eradication may be asked for criminal liability against the corporation so that further interpretation is required.
PENGATURAN PEMBIAYAAN USAHA MIKRO DAN KECIL OLEH PEMERINTAH SEBAGAI UPAYA STRATEGIS DALAM MENDUKUNG PEREKONOMIAN NASIONAL
Authors: Sanjiwani Kadek Ary Putri , Nurmawati Made 
Published: July 2021

Studi ini bertujuan mengkaji kewenangan Pemerintah untuk menyediakan pembiayaan bagi Usaha Mikro dan Kecil serta terpenuhinya persyaratan dalam rangka memperoleh pembiayaan. Metode yang digunakan dalam studi adalah metode penelitian hukum normatif dengan menggunakan pendekatan perundang – undangan. Hasil studi menunjukkan bahwa ketentuan Pasal 21 Ayat (1) Undang – Undang Nomor 20 Tahun 2008 tentang Usaha Mikro, Kecil, dan Menengah yang mengatur tentang pembiayaan Usaha Mikro dan Kecil tampak kabur sehingga menimbulkan multitafsir dalam hal kewenangan Pemerintah untuk menyediakan pembiayaan. Kemudian dalam ketentuan Pasal 23 huruf c tidak adanya ketentuan yang mengatur secara eksplisit syarat – syarat yang harus dipenuhi Usaha Mikro dan Kecil guna memperoleh pembiayaan. Agar Usaha Mikro dan Kecil dapat memperoleh pembiayaan dengan ketentuan aturan yang jelas memerlukan suatu kepastian hukum sehingga tercapainya kemanfaatan, dan keadilan hukum dalam usaha menjaga stabilitas Usaha Mikro dan Kecil sebagai pendukung strategis pembangunan perekonomian nasional.
This study aims to examine the Government's authority to provide financing for Micro and Small Enterprises and to fulfill the requirements in order to obtain financing. The method used in the study is a normative legal research method using the statutory approach. The study results show that the provisions of Article 21 Paragraph (1) of Law Number 20 Year 2008 concerning Micro, Small and Medium Enterprises that regulate Micro and Small Enterprise financing appear to be blurred, giving rise to multiple interpretations in terms of the Government's authority to provide financing. In the provisions of Article 23 letter c there is no provision that explicitly regulates the conditions that must be met by Micro and Small Enterprises in order to obtain financing. So that Micro and Small Enterprises can obtain funding with clear rules requiring legal certainty, the benefits and legal justice in efforts to maintain the stability of Micro and Small Enterprises as strategic supporters of national economic development can be achieved.