bluuebunny/crossref_metadata_2025_split huggingface dataset:
Harnessing Artificial Intelligence for Health Message Generation: The Folic Acid Message Engine
Authors: Schmälzle Ralf , Wilcox Shelby 
Published: November 2021

Background
Communication campaigns using social media can raise public awareness; however, they are difficult to sustain. A barrier is the need to generate and constantly post novel but on-topic messages, which creates a resource-intensive bottleneck.

Objective
In this study, we aim to harness the latest advances in artificial intelligence (AI) to build a pilot system that can generate many candidate messages, which could be used for a campaign to suggest novel, on-topic candidate messages. The issue of folic acid, a B-vitamin that helps prevent major birth defects, serves as an example; however, the system can work with other issues that could benefit from higher levels of public awareness.

Methods
We used the Generative Pretrained Transformer-2 architecture, a machine learning model trained on a large natural language corpus, and fine-tuned it using a data set of autodownloaded tweets about #folicacid. The fine-tuned model was then used as a message engine, that is, to create new messages about this topic. We conducted a web-based study to gauge how human raters evaluate AI-generated tweet messages compared with original, human-crafted messages.

Results
We found that the Folic Acid Message Engine can easily create several hundreds of new messages that appear natural to humans. Web-based raters evaluated the clarity and quality of a human-curated sample of AI-generated messages as on par with human-generated ones. Overall, these results showed that it is feasible to use such a message engine to suggest messages for web-based campaigns that focus on promoting awareness.

Conclusions
The message engine can serve as a starting point for more sophisticated AI-guided message creation systems for health communication. Beyond the practical potential of such systems for campaigns in the age of social media, they also hold great scientific potential for the quantitative analysis of message characteristics that promote successful communication. We discuss future developments and obvious ethical challenges that need to be addressed as AI technologies for health persuasion enter the stage.
Clinical Effectiveness and Cost-effectiveness of Videoconference-Based Integrated Cognitive Behavioral Therapy for Chronic Pain: Randomized Controlled Trial
Authors: Taguchi Kayoko , Numata Noriko , Takanashi Rieko , Takemura Ryo , Yoshida Tokiko , Kutsuzawa Kana , Yoshimura Kensuke , Nozaki-Taguchi Natsuko , Ohtori Seiji , Shimizu Eiji 
Published: November 2021

Background
Cognitive behavioral therapy is known to improve the management of chronic pain. However, the components of this therapy are still being investigated and debated.

Objective
This study aimed to examine the effectiveness of an integrated cognitive behavioral therapy program with new components (attention-shift, memory work, video feedback, and image training) delivered via videoconferencing.

Methods
This study was unblinded and participants were recruited and assessed face-to-face in the outpatient department. We conducted a randomized controlled trial for chronic pain to compare 16 weekly videoconference-based cognitive behavioral therapy (vCBT) sessions provided by a therapist with treatment as usual (TAU). Thirty patients (age range, 22-75 years) with chronic pain were randomly assigned to either vCBT (n=15) or TAU (n=15). Patients were evaluated at week 1 (baseline), week 8 (midintervention), and week 16 (postintervention). The primary outcome was the change in pain intensity, which was recorded using the numerical rating scale at 16 weeks from the baseline. Secondary outcomes were pain severity and pain interference, which were assessed using the Brief Pain Inventory. Additionally, we evaluated disability, pain catastrophizing cognition, depression, anxiety, quality of life, and cost utility.

Results
In the eligibility assessment, 30 patients were eventually randomized and enrolled; finally, 15 patients in the vCBT and 14 patients in the TAU group were analyzed. Although no significant difference was found between the 2 groups in terms of changes in pain intensity by the numerical rating scale scores at week 16 from baseline (P=.36), there was a significant improvement in the comprehensive evaluation of pain by total score of Brief Pain Inventory (–1.43, 95% CI –2.49 to –0.37, df=24; P=.01). Further, significant improvement was seen in pain interference by using the Brief Pain Inventory (–9.42, 95% CI –14.47 to –4.36, df=25; P=.001) and in disability by using the Pain Disability Assessment Scale (–1.95, 95% CI –3.33 to –0.56, df=24; P=.008) compared with TAU. As for the Medical Economic Evaluation, the incremental cost-effectiveness ratio for 1 year was estimated at 2.9 million yen (about US $25,000) per quality-adjusted life year gained.

Conclusions
The findings of our study suggest that integrated cognitive behavioral therapy delivered by videoconferencing in regular medical care may reduce pain interference but not pain intensity. Further, this treatment method may be cost-effective, although this needs to be further verified using a larger sample size.

Trial Registration
University Hospital Medical Information Network UMIN000031124; https://tinyurl.com/2pr3xszb
Citation Advantage of Promoted Articles in a Cross-Publisher Distribution Platform: 36-Month Follow-up to a Randomized Controlled Trial
Authors: Kudlow Paul , Brown Tashauna , Eysenbach Gunther 
Published: November 2021

Background
There are limited evidence-based strategies that have been shown to increase the rate at which peer-reviewed articles are cited. In a previously reported randomized controlled trial, we demonstrated that promotion of article links in an online cross-publisher distribution platform (TrendMD) persistently augments citation rates after 12 months, leading to a statistically significant 50% increase in citations relative to the control.

Objective
This study aims to investigate if the citation advantage of promoted articles upholds after 36 months.

Methods
A total of 3200 published articles in 64 peer-reviewed journals across 8 subject areas were block randomized at the subject level to either the TrendMD group (n=1600) or the control group (n=1600) of the study. Articles were promoted in the TrendMD Network for 6 months. We compared the citation rates in both groups after 36 months.

Results
At 36 months, we found the citation advantage endured; articles randomized to TrendMD showed a 28% increase in mean citations relative to the control. The difference in mean citations at 36 months for articles randomized to TrendMD versus the control was 10.52 (95% CI 3.79-17.25) and was statistically significant (P=.001).

Conclusions
To our knowledge, this is the first randomized controlled trial to demonstrate how a postpublication article promotion intervention can be used to persistently augment citations of peer-reviewed articles. TrendMD is an efficient digital tool for knowledge translation and dissemination to targeted audiences to facilitate the uptake of research.
A Critical Review on Nanoscience Advancement: In Treatment of Viral Infection
Authors: Chaudhary Kajal , Parihar Shweta , Sharma Devender 
Published: November 2021

Viral contaminations speak to a general medical issue and one of the main sources of worldwide mortality. A large portion of the antiviral medications have low permeability, low dissolvability and other related physical properties which make them less efficient for the antiviral treatment. To conquer these constraints, different nanomedicine stages have been planned. Nanomaterials offer special physico-chemical properties that have various advantages for medicate conveyance as perfect devices for viral treatment. This review focuses on the currently used medicines used in viral infection, presents a broad overview of the application of nanosized materials for the treatment of common viral infections and shed light on the potential of nanotechnology to provide more effective treatment for HIV, Herpes simplex virus, Influenza virus and Hepatitis C virus. The action of antiviral medications could be improved with nanomedicine formulations. As the physicochemical properties of nanocarriers can empower their capacity to target the specific sites. When it comes to structuring nanocarriers, size is the most important factor and the nanoparticles can permit the controlled delivery kinetics, enhanced bioavailability, altered pharmacokinetics, and less side effects. Nanocarriers that build them appealing candidates for antiviral drug such as Improves bioavailability of the encapsulated actives, controlled release, reduce the toxicity associated with the anti-viral drugs. One of the important physicochemical properties mainly size is the most important design factor for nanocarriers for anti-viral drug delivery to the specific sites. Nanobased drug delivery also leads to enhance the potential of currently approved antiviral drugs.
Keywords: Nanotechnology, HIV, Hepatits virus, Influenza, HSV
Prevalence of Risk Factors for Stroke Patients at UKI General Hospital in 2015
Authors: Aritonang Christina Roseville Lasma , Pariama Ganda 
Published: November 2021

Stroke is a disease caused by disturbance of brain blood circulation influenced by many risk factors such as age, blood pressure, blood sugar, and blood lipid level. This study aimed to determine the prevalence of risk factors that contribute to stroke incidence in stroke patients hospitalized at UKI General Hospital in 2015. The design of this study is retrospective with research methodology descriptive observational. The sample in this study is all cases of a stroke at UKI General Hospital in 2015. The result showed that the highest type of stroke is ischemic stroke (77%) with the largest age group of 40-60 years (51.3%), male sex (60 people). Prevalence risk factors are hypertension stage 2 (52,2%), blood glucose level <200 mg/dl (81,4%) low total cholesterol level (47,8%), LDL level borderline high (23%), low HDL level (44,2%).
Keywords: stroke, risk factor, the prevalence
Acute and subacute toxicity assessment of an aqueous extract of Crotalaria retusa (Fabaceae) in Swiss mice and Wistar rats
Authors: GOH BI Lane Adrien , TOTO Noel Kouame , ZAHOUI Ouga Stanislas , KASSI Yomalan , NENE Bi Semi Anthelme , TRAORE Flavien 
Published: November 2021

The present study is a contribution to the enhancement of Ivorian traditional medicine, by carrying out bio-tolerance tests of an aqueous extract of the aerial parts of Crotalaria retusa (EACr) in mice and rats according to the guidelines of the Organization for Economic Co-operation and Development (OECD) 423 and 407, respectively. The doses of 2000 and 5000 mg/kg of body weight (BW) of the extract were used for acute toxicity. For subacute toxicity which lasted 28 days, doses of 500, 1000, and 2000 mg/kg BW have been used. The administration of the single doses of 2000 and 5000 mg/kg BW of EACr did not provoke death in female mice in the acute toxicity setting. For subacute toxicity in rats (male and female), the administration of repetitive doses of 500, 1000, and 2000 mg/kg BW of EACr over a period of 28 days did not cause death in these animals. In females, these doses caused weight loss and a decrease in platelets. The extract reduced the activity of AST in both sexes of rats. The findings also showed that this extract would possess a nephroprotective property in male and female rats.
Keywords: Crotalaria retusa, Acute and subacute toxicities, Wistar rat, Swiss mice
Cross-sectional Survey on Online Learning during COVID-19 Pandemic in Bangladesh
Authors: Bhattacherjee Devaroti , Akash Sajidur Rahman , Saiky Sanjida Islam , Chaity Nur E Naznin , Islam MD. Ariful , Jahan Nusrat , Chowdhury Imtiaj Hossain 
Published: November 2021

The educational system across the world had drastically been affected due to the pandemic outbreak of COVID-19. In this circumstance, Teaching and learning shifted from traditional way which involves face-to-face interaction among teachers and students physically in a classroom, to online learning either synchronously or asynchronously. Therefore, the aim of this study is to monitor the level of students’ perception towards online learning during the ongoing COVID-19 pandemic situation. The study adopted the way of quantitative approach by conducting a survey which was collected via a standardized online questionnaire. Data collected from 699 respondents were analyzed using SPSS 23 software. In spite of having been failed to get theoretical and practical experience as well as expected results, majority of the respondents had positive perceptions towards online learning and accepted this as the new method of learning with online application tools. The outcomes of the study will facilitate educational institutions and policy makers to take this online learning process to the next level in a prospective way.
Keywords: Online Learning, COVID-19, Pandemic, Bangladesh.
Disclosure of Interim Review Reports: Do Interim Going Concern Conclusions Have Information Content?
Authors: Grosse Matthew , Scott Tom 
Published: November 2021

SUMMARY
This paper examines the information content of interim review assurance in the Australian mandatory disclosure setting. First, we find a strong negative market reaction to interim going concern conclusions (IGCC) contained in the review of interim financial statements. Second, we find no significant difference between the market reaction to IGCCs and annual going concern opinions (AGCO) received at the annual report audit. Finally, we show IGCCs are significant predictors of subsequent AGCOs, and provide incremental information from the previous annual report audit opinion. Overall, these results contribute to the literature on the benefits of mandatory interim assurance by showing that going concern conclusions contained in interim financial statements provide investors with new and relevant information.
JEL Classifications: G38; M42; M48.
Evaluating the Impact of the Accounting Doctoral Scholars Program on Academic Accounting in the U.S.
Authors: Pyzoha Jonathan S. , Fogarty Timothy J. 
Published: November 2021

ABSTRACT
The accounting establishment and AICPA Foundation responded to an inadequate supply of new accounting faculty by creating the Accounting Doctoral Scholars (ADS) program. Between 2009 and 2018, the $17 million program enabled 105 practitioners to become audit and tax faculty. Based on market data and an ADS participant survey, we find an increase in doctoral graduates at ADS and non-ADS schools relative to pre-ADS years, and unmet demand for audit has decreased after ADS, whereas tax remains in need. Compared to the market, ADS graduates experienced somewhat better placements by moving up to more prestigious strata and were more likely to place at schools with a doctoral program. Additionally, we present results for ADS students' motivations, degree completion time, and differences between audit and tax participants. Our findings have important implications for academic accounting, business schools, regulators, and policymakers. We provide important context for changes in market trends preceding COVID-19.
Effect of fertilizer and cultivation systems and herbicide application on soil biological activity under spring barley cultivation and its yield
Authors: Shuvar Ivan , Korpita Hanna , Lipińska Halina , Wyłupek Teresa , Sosnowska Małgorzata , Bieske-Matejak Alicja 
Published: November 2021

The results of the research devoted to the change of the biological composition of the soil under the conditions of activation of microbiological vital activity and increase in the number of earthworms in the technology of spring barley cultivation are presented. It was found that the organic system of growing crops against the background of manure, cereal straw and green manure in comparison with the organo-mineral system obtained a positive dynamics of decomposition of linen tissue and the development of earthworms in the soil.The highest grain yield was formed by agrocenosis of spring barley with the introduction of Lancelot 450 WG – 0.033 kg·ha–1 + Axial 50 EC – 1 dm3·ha–1 (tube exit phase) – 4900 kg·ha–1 and 4700 kg·ha–1 for organo-mineral and organic fertilizer systems in accordance.
A Ação Popular e a sua aplicação em Sergipe
Authors: Couto dos Santos João Paulo , Espinoza Fran 
Published: November 2021

A ação popular é um instrumento jurídico que é utilizado quando o cidadão visa defender o patrimônio público, a moralidade administrativa e o meio ambiente, por conta disso o estudo do tema aplicado no estado de Sergipe é de grande importância no campo jurídico e social. O presente trabalho, tem como objetivo investigar a ação popular, analisando os temas tratados em seus processos e a função das partes nestes. Pretende-se responder as seguintes perguntas: Quais os temas mais tratadas no estado? Qual o comportamento dos participantes do processo da ação popular? Para a pesquisa foi escolhida a metodologia qualitativa que permitiu a devida análise do tema, a partir da consulta de bases teóricas como livros, artigos científicos e principalmente a análise de processos distribuídos no estado de Sergipe nos anos de 2018 e 2019 que estavam na classe 66 – ação popular, no total foram 76 processos. Os dados processuais necessários para análise foram solicitados pelo Sistema de Informação ao Cidadão – SIC, presente no site do Tribunal de Justiça de Sergipe. Dano ao erário foi o assunto mais recorrente de todos os processos analisados, em 27,6% estava presente esta temática. A Ação Popular no estado de Sergipe, possui um número pequeno de processos, dada a importância e relevância que essa ação possui, isso por conta da falta de conhecimento a respeito dessa ação, o que demonstra ainda mais o interesse de se estudar como se aplica essa ação e como é a atuação dos participantes em seu processo.
What Does a Humane Infrastructure for Research Look Like?
Authors: Carpi Estella 
Published: November 2021

In this intervention I make two main suggestions to humanize refugee research. First, the tendency to select “research hotspots” as field sites—where researchers tend to approach the same interviewees and spaces—should not only be called out and avoided, but battled against. Second, I suggest that refugee research should collaborate directly with other studies of social, political, and economic phenomena in an effort to not make displacement the sine qua non condition for doing research but, instead, only one of the many conditions a human being can inhabit within receiving societies. Pursuing this aim will be easier when studies on forced migration do not become compartmentalized and develop in isolation from other disciplines and research groups.
Mnemonic Aids in Linguodidactic Discourse
Authors: Kalashnikov A. V. 
Published: November 2021

The article examines modern English memory aids as part of linguodidactic discourse in teaching English, and the patterns of mnemonic devices represented by sentence, acronym, abbreviation and verse. The empirical material of the research incorporates 54 units. The focus is made on an extensive number of mnemonics compiled as a meaningful text and the patterns of the devices in the form of a sentence, and the mnemonic acronyms homonymous to general vocabulary, i. e. homoacronyms. At that, the mnemonic aids which are not similar to other words, are not so often used as mnemonic devices. The mnemonic devices in the paper have been studied on the basis of the English and Russian sources published in the 21stcentury.Mnemonic devices have become part of research only in recent years. Previously mnemonics were studied within the framework of pedagogical discourse in teaching Geography, Biology, Astronomy, History, and Music. In the present research the mnemonics related to teaching English were distributed by structure. Afterwards, mnemonic sentences and the mnemonics homonymous to the existing lexemes were identified. The analysis of the structures showed the domination of the mnemonics structured as sentences and homoacronyms. 54 units of mnemonics under study were presented in the form of 22 sentences, 3 verses, 17 acronyms and 12 abbreviations. The most common structure proved to be a sentence, while the least common one was verse. The mnemonics considered contained only 13 units which were not sentences or homoacronyms: 12 abbreviations and 1 acronym of primary nomination. The examination of the structures showed the domination of the mnemonics organized as a sentence or a homoacronym. The research confirms the assumptions made earlier on the frequent use of sentence mnemonics, which, as it turned out, exceed the shares of the other mnemonic patterns. In their turn, homoacronyms made up a larger share compared to acronyms and abbreviations with no reference to general English words or verse. Thus, we can consider these structures (sentences and homoacronyms) within English teaching as part of pedagogical discourse. To sum it up, while compiling mnemonic aids, preference should be given to sentences or homoforms based on the vocabulary, while verses and abbreviations might be used economically. The article has also revealed additional features of mnemonics, in particular applying asyndeton in acronyms and abbreviations, the average number of 3 or 4 components in a mnemonic aid. Studying such structures will contribute to examining shortened forms and functioning of mnemonics in linguodidactic discourse.
School Buildings for the 21st Century: Some Features of New School Buildings in Iceland
Authors: Sigurðardóttir Anna Kristín , Hjartarson Torfi 
Published: November 2021

The aim of this study is to identify features of change in the recent design of school buildings in Iceland, and how they might affect teaching practices. Environmental and architectonic features characterising school buildings designed and built at the beginning of the 21st century are examined in light of challenges involving architecture, educational ideology, school policy and digital technology. The sample for the study consists of 20 schools located in four municipalities. Four of the school buildings were developed and built in this century, while the other 16 were designed in the 20th century. The design of all of the buildings wasexplored and reviewed by a multidisciplinary team. Data was collected by observations and photography at each school site, as well as by reviewing technical documents. The relationship between school design and school practices was studied through a questionnaire survey among all teachers, in order to find out whether teachers working in new environmentsdiffer from teachers in more traditional classroom settings. The results indicate a clear shift in the design of educational buildings. Flexibility, flow, openness and teamwork seem to guide recent school design. Clusters of classrooms or open spaces, transparent or movable boundaries, as well as shared spaces allowing for manifold interactions in flexible groupsseem to be replacing traditional classrooms along confining corridors. Teachers working in open classroom environments collaborate more often than their counterparts. Teaching practices are also characterised by more opportunities for pupils to choose between tasks and enjoy more variation regarding group division and workspace arrangements.