bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recognition and development of customized cosmetics for military trainees in 20s and 30s in Republic of Korea
Authors: Lee Jinkyung , Kwon Ki Han 
Published: August 2021

AbstractBackgroundFor the health of the skin, social standards have been changed to increase the public's interest in achieving perfect skin. With the diversification of consumer needs, the reorganized core market for demand pursues the attributes of customization that bring the individual ego and product image to match through aggressive consumer needs.ObjectivesTherefore, in this study, we conducted a questionnaire to 450 men in their 20s and 30s, Chuncheon City, Gangwon‐do, Republic of Korea, focused on the fact that customized cosmetics drive individuals and optimization.MethodsStatistical processing of materials collected by the data analysis method is analyzed using the SPSS (Statistical Package for Social Science) WIN25.0 statistical package program through the process of data coding and data cleaning.ResultsAs a result, “I think I need customized cosmetics for me.” 3.91 (SD = 1.19), and it seems that the number of custom cosmetics used will increase in the future. “3.99 (SD = 1.06) It was the highest in terms of points. Also, I would like to use PX's men's custom cosmetics when they are released.” The average was 4.34 (SD = 0.91), which was the highest. Comprehensive research results of P <0 .001 and above suggested the possibility of developing customized cosmetics for men.ConclusionTherefore, this requires continuous research on personalized bespoke cosmetics according to work and usage characteristics, and PX custom products for future soldiers should be developed. In the future, the researcher plans to continue to study the recognition and development potential of customized cosmetics for female military personnel in South Korea in subsequent research.
Decreased fetal heart rate variability and maternal combined dose of sodium valproate and phenytoin
Authors: Makino Marie , Osato Kazuhiro , Kuriyama Moeko , Nagao Kenji , Ikeda Tomoaki 
Published: August 2021

SynopsisA rare combination of anti‐epileptic drugs, sodium valproate and phenytoin prescribed to a pregnant woman with epilepsy might have decreased the fetal heart rate variability.
3D multi‐resolution deep learning model for diagnosis of multiple pathological types on pulmonary nodules
Authors: Fu Yu , Xue Peng , Zhao Peng , Li Ning , Xu Zhuodong , Ji Huizhong , Zhang Zhili , Cui Wentao , Dong Enqing 
Published: August 2021

AbstractTo accurately diagnose multiple pathological types of pulmonary nodules based on lung computed tomography (CT) images, a multi‐resolution three‐dimensional (3D) multi‐classification deep learning model (Mr‐Mc) was proposed. The Mr‐Mc model was constructed by using our own constructed lung CT image dataset of pulmonary nodules with clinical pathological information (LCID‐CPI), which can accurately diagnose inflammation, squamous cell carcinoma, adenocarcinoma, and other benign diseases. In order to process nodules with different sizes, a multi‐resolution extraction method was proposed to extract 3D volume data with different resolutions from lung CT images. The Mr‐Mc was composed of three different resolution networks, each of which has input volume data of a specific resolution. Experiments showed that the constructed Mr‐Mc model can achieve an average accuracy of 0.81 on LCID‐CPI. Besides, the Mr‐Mc model can also achieve a high accuracy of 0.87 on the Lung Image Database Consortium and Image Database Resource Initiative dataset.
Systems Engineering Roles in Software Organizations Delivering Service Products
Authors: Bouyaud Mickael , White Brian E. 
Published: August 2021

ABSTRACTThe software industry has been experiencing several transformations. Development teams now often autonomously deliver business capabilities to software service systems. The Unicorn Project, a best‐seller, tells how a retail company transformed into an Agile and DevOps organization. This paper uses a model from the systems engineering toolset to understand those organizational changes and proposes an evolution of the systems engineering discipline to increase the value provided by this type of organization.
System Test Approach for Complex Software Systems
Authors: Mirchandani Chandru 
Published: August 2021

ABSTRACTThere is a need to develop a system approach to develop an adaptive model (Mirchandani 2010) by which the changes in the testing and upgrade or ‘problem‐fix’ processes for complex software are monitored in real‐time and incorporated in the development of reliability models for software systems. As system engineers it is our goal to develop, elegant designs that will implement the required capability, i.e., produce the intended result (IW2021 – BT), be both robust and efficient, and limit unintended consequences. Towards this goal, system engineers strive to minimize technical debt and maximize the relevance of the needed capabilities for successful implementation of the system. If one was to follow the classical system engineering process, the system must meet certain needs. If there was a need for the system, be it perceived or an actual problem, the system engineering process, which is constantly evolving, must be enhanced to meet the needs of the 21st century.It is obvious that testing is necessary to validate that all the critical processes are functional and satisfy the system requirements allocated to software. However, there is a risk if the software is tested to a perceived operational environment based on theoretical workloads.
Effects of pharmacist interventions on heart failure outcomes: A systematic review and meta‐analysis
Authors: Arunmanakul Poukwan , Kengkla Kirati , Chaiyasothi Thanaputt , Phrommintikul Arintaya , Ruengorn Chidchanok , Permsuwan Unchalee , Thakkinstian Ammarin , Page Robert L. , Munger Mark A. , Nathisuwan Surakit , Chaiyakunapruk Nathorn 
Published: August 2021

AbstractHeart failure (HF) patients tend to have multiple comorbidities resulting in complex therapy regimens and medication adherence issues. Nevertheless, the evidence of pharmacists' contributions to improving clinical outcomes in HF is limited. To assess the impact of pharmacist intervention on all‐cause hospitalization, mortality, and quality of life (QoL) in HF) patients. A systematic search of PubMed, Embase, the Cochrane Central Register of Controlled Trials, Scopus, and CINAHL was performed up to April 30, 2020. Randomized controlled trials (RCTs) evaluating pharmacist interventions compared with usual care in adult HF patients were selected. Data were extracted independently by two authors. Random effects meta‐analysis models were used to pool treatment effects and confidence intervals (CIs). Twenty‐nine trials identified 6965 predominantly HF with reduced ejection fraction (HFrEF) patients. The average age was 72.0 years (interquartile range [IQR] 66.0‐76.0) and 48% were men (IQR 40.0%‐68.0%). The majority were New York Heart Association (NYHA) Functional class (FC) II‐III with median left ventricular ejection fraction (LVEF) of 38.5% (IQR 34.5%‐49.5%). Pharmacist interventions were associated with a significant reduction of all‐cause mortality (risk ratio [RR] 0.72; 95% CI 0.58‐0.89; P = 0.003) and all‐cause hospitalizations (RR 0.87; 95% CI 0.77‐0.99; P = 0.041). A significant increase in the 36‐item Short form Health survey (SF‐36) on role physical (Mean deviation [MD], 8.5; 95% CI, 1.00 to 16.01, P = 0.026) and mental health (MD, 7.49; 95% CI, 3.88 to 11.10, P < 0.001) were observed. In addition, a significant improvement in Minnesota Living with Heart Failure Questionnaire score was observed (MD ‐3.55; 95% CI ‐6.28 to −0.82; P = 0.01). Pharmacist interventions in patients with HF significantly reduced all‐cause mortality and hospitalizations and improved QoL. Integration of a pharmacist into a HF care team or care pathway should be strongly considered as an important element of a multidisciplinary team.
Impact of first and second shift tele‐critical care pharmacy services and virtual rounds on interventions at Atrium Health Lincoln
Authors: Griffiths Carrie L. , Kosmisky Desiree E. , Everhart Sonia S. , Marshall Karen S. , Knight Charlene P. 
Published: August 2021

AbstractBackgroundIn 2015, Atrium Health (AH) established second shift pharmacy services in the tele‐critical care (TCC) setting to optimize medication therapy and serve as a drug information resource to facilities across the health care system. TCC pharmacy services expanded to the first shift in July 2017. In September 2017, the first shift pharmacist began participating in virtual multidisciplinary rounds 1 day per week, which increased to 3 days per week in October 2019 at AH Lincoln, a community hospital with a 10‐bed intensive care unit (ICU).MethodsThis was a nonrandomized retrospective cohort study of adult ICU patients at AH Lincoln across two different time periods. The primary outcome was the number and type of pharmacy interventions made on rounding day(s) vs nonrounding days and first vs second shifts. Data are reported using descriptive statistics.ResultsDuring time period 1, a total of 1174 patients were admitted to the ICU for a total of 2115 patient days, with an average length of stay (LOS) of 1.8 days (SD ± 1.8 days). During time period 2, a total of 812 patients were admitted to the ICU for a total of 1775 patient days with an average LOS of 2.2 days (SD ± 2.7 days). During time period 1, a total of 753 interventions (297 on first shift and 456 on second shift) were performed as compared to time period 2, which had 1276 interventions (816 on first shift and 460 on second shift). For both time periods, the most common intervention on the first shift was medication management (45%) vs glycemic control (36%) on the second shift.ConclusionsThe addition of TCC pharmacy services to AH Lincoln has resulted in a positive impact on medication management, with the largest impact demonstrated through virtual rounding by the first shift TCC pharmacist.
Impact analysis of virtual ambulatory transplant pharmacists during COVID‐19
Authors: Park Lindsay , Kim Ju Hee , Waldman Georgina , Marks Christin Rogers , Clark Jacqueline E. 
Published: August 2021

AbstractIntroductionDuring the coronavirus disease 2019 (COVID‐19) pandemic, transplant centers were challenged to meet the demand for new telemedicine strategies. The ability of lung transplant providers (LTP) to conduct face‐to‐face clinic visits for high‐risk immunocompromised patients, such as lung transplant recipients (LTR), was limited. Through the implementation of comprehensive medication management visits, pharmacists were able to assist LTP in the transition to telemedicine.MethodsA retrospective chart review of telephone encounters from cardiothoracic (CT) transplant pharmacists at our center from March to September 2020 was completed. LTR scheduled for clinic visits with LTP were called prior to the visit by CT transplant pharmacists who conducted medication list reviews, adherence assessments, and medication access assistance. Clinical recommendations were communicated directly to the LTP and documented in patient electronic medical records. The primary outcome was the number of pharmacist‐driven clinical interventions. Secondary endpoints included the clinical severity and value of service of each intervention, percentage of accepted recommendations, patient cost savings interventions, prevention of adverse events, and avoidance of inappropriate doses.ResultsFrom March to September 2020, the CT transplant pharmacists conducted 385 virtual visits on 157 LTR with a median of 20 minutes spent per visit. There were 891 total interventions made by CT transplant pharmacists, including 778 medication discrepancies identified. Over 60% of encounters demonstrated some form of medication error and over 55% of encounters exhibited value of pharmacy services.ConclusionImplementation of CT transplant pharmacist telehealth visits has potential for increased patient access to pharmacy care and improved accuracy of medication lists. When focusing on the severity of errors and value of services, most demonstrated a level of significance. Further investigation is needed to analyze the impact of this service on patient outcomes as well as cost‐effectiveness.
Sequential Therapy With Recombinant Human IGF-1 Followed by Risedronate Increases Spine Bone Mineral Density in Women With Anorexia Nervosa: A Randomized, Placebo-Controlled Trial
Authors: Haines Melanie Schorr , Kimball Allison , Meenaghan Erinne , Bachmann Katherine N , Santoso Kate , Eddy Kamryn T , Singhal Vibha , Ebrahimi Seda , Dechant Esther , Weigel Thomas , Ciotti Lori , Keane Robert J , Gleysteen Suzanne , Mickley Diane , Bredella Miriam A , Tan Can Ozan , Gupta Rajiv , Misra Madhusmita , Schoenfeld David , Klibanski Anne , Miller Karen K 
Published: August 2021

ABSTRACT
Anorexia nervosa is complicated by low bone mineral density (BMD) and increased fracture risk associated with low bone formation and high bone resorption. The lumbar spine is most severely affected. Low bone formation is associated with relative insulin-like growth factor 1 (IGF-1) deficiency. Our objective was to determine whether bone anabolic therapy with recombinant human (rh) IGF-1 used off-label followed by antiresorptive therapy with risedronate would increase BMD more than risedronate or placebo in women with anorexia nervosa. We conducted a 12-month, randomized, placebo-controlled study of 90 ambulatory women with anorexia nervosa and low areal BMD (aBMD). Participants were randomized to three groups: 6 months of rhIGF-1 followed by 6 months of risedronate (“rhIGF-1/Risedronate”) (n = 33), 12 months of risedronate (“Risedronate”) (n = 33), or double placebo (“Placebo”) (n = 16). Outcome measures were lumbar spine (1° endpoint: postero-anterior [PA] spine), hip, and radius aBMD by dual-energy X-ray absorptiometry (DXA), and vertebral, tibial, and radial volumetric BMD (vBMD) and estimated strength by high-resolution peripheral quantitative computed tomography (HR-pCT) (for extremity measurements) and multi-detector computed tomography (for vertebral measurements). At baseline, mean age, body mass index (BMI), aBMD, and vBMD were similar among groups. At 12 months, mean PA lumbar spine aBMD was higher in the rhIGF-1/Risedronate (p = 0.03) group and trended toward being higher in the Risedronate group than Placebo. Mean lateral lumbar spine aBMD was higher, in the rhIGF-1/Risedronate than the Risedronate or Placebo groups (p &lt; 0.05). Vertebral vBMD was higher, and estimated strength trended toward being higher, in the rhIGF-1/Risedronate than Placebo group (p &lt; 0.05). Neither hip or radial aBMD or vBMD, nor radial or tibial estimated strength, differed among groups. rhIGF-1 was well tolerated. Therefore, sequential therapy with rhIGF-1 followed by risedronate increased lateral lumbar spine aBMD more than risedronate or placebo. Strategies that are anabolic and antiresorptive to bone may be effective at increasing BMD in women with anorexia nervosa. © 2021 American Society for Bone and Mineral Research (ASBMR).
The valuation effects of unit versus share‐only IPOs
Authors: Chen Mengxi 
Published: August 2021

AbstractUnits consist of shares and warrants. Some firms issue units in initial public offerings (IPOs) after which warrant holders can exercise warrants and purchase shares from the issuer. Why do firms choose to issue units instead of only shares? I answer this question based on Merton's investor recognition model. Firms lacking pre‐IPO publicity can benefit from an increase in investor recognition. I find that unit firms have less pre‐IPO publicity than share‐only firms. Separate trading between warrants and shares and eventual exercise of the warrants will increase the number of shareholders and therefore firm value.
Using participatory culture‐specific consultation to support the mental health needs of summer camp staff
Authors: Wright Brittany J. , Azmat Alia , Aggarwal Aashna , Radding Matthew , Sieplinga Joel , Case Amanda , Khalil Amani 
Published: August 2021

AbstractNearly 30% of all U.S. youth attend summer camp each year, making it one of the broadest reaching out‐of‐school‐time interventions in the country. Camp provides a space for seasonal employees, who are often emerging adults, to explore work values and identity, engage in mentoring and support opportunities, and stay connected to a community larger than themselves. However, research on camp experiences also suggests camp settings and expectations around emotional and physical care can cause counselors to experience burnout, compassion fatigue, and reduced job satisfaction. Using participatory culture‐specific consultation, the current study addressed a gap in the literature about systemic interventions to manage camp counselor mental health by designing, implementing, and evaluating a mental health consultation model at one of the largest YMCA summer camps in the country. Results suggest the intervention effectively addressed certain administrator and staff needs; results also suggest the model could be refined to more effectively respond to the particular contextual challenges of summer camps. Implications and recommendations for other summer camps are discussed.
Telehealth for genetic counseling: A systematic evidence review
Authors: Danylchuk Noelle R. , Cook Lola , Shane‐Carson Kate P. , Cacioppo Cara N. , Hardy Melanie W. , Nusbaum Rachel , Steelman Susan C. , Malinowski Jennifer 
Published: August 2021

AbstractTelehealth options, such as telephone counseling or videoconferencing, for service delivery in genetic counseling are becoming more widely accepted. However, until now, there has not been a systematic review of the literature focused specifically on genetic counseling outcomes for telehealth. We performed a systematic evidence review to compare telehealth genetic counseling (THGC), including videoconferencing and telephone counseling, across specialties to in‐person genetic counseling (IPGC) for a range of outcomes specific to patient and provider experiences and access to care. Several biomedical databases were queried up to January 11, 2021, to identify original research evaluating THGC. Through this search, 42 articles met the inclusion criteria including 13 randomized controlled trials and 29 non‐randomized observational studies encompassing 13,901 patients. Most included studies focused only on cancer genetic counseling; however, adult, pediatric, and prenatal specialties were also represented. The majority of studies evaluated patient and/or access to care outcomes. Though most studies reported high patient satisfaction with THGC, as well as comparable rates of trust and rapport, confidence in privacy, health behavior changes, and psychosocial outcomes, few represented diverse populations. Data of provider experiences were limited and varied with more disadvantages noted compared with patient experiences, particularly in studies involving telephone genetic counseling. Studies consistently reported a decrease in the patients’ costs and time required for travel when patients are seen via THGC compared to IPGC with a similar reduction in costs to the health system. Overall, results from our evidence synthesis suggest THGC is non‐inferior or comparable to IPGC across many domains, even considering that many of the studies included in this review were conducted with telehealth systems, notably videoconferencing, that were less robust and reliable than what is available today. There are notable limitations within this body of literature, leading to potential uncertainty in the generalizability of our analysis. We outline several recommendations for future studies.
Morphological basis for maternal nutrient provision to embryos in the viviparous fish Ataeniobius toweri (Teleostei: Goodeidae)
Authors: Uribe Mari Carmen , Cerda‐Jardón Paola‐Ivonne , Blackburn Daniel G. 
Published: August 2021

AbstractIn viviparous Mexican fishes of the family Goodeidae, embryos develop in the maternal ovarian lumen. They typically absorb maternal nutrients during gestation by means of “trophotaeniae,” that is, specialized, elongated extensions of the hindgut that are exposed to the fluids, which occupy the ovarian lumen. The sole exception is Ataeniobius toweri, whose embryos lack trophotaeniae but are nevertheless matrotrophic. Thus, how its embryos obtain maternal nutrients is unclear. We studied a series of non‐pregnant and pregnant ovaries of A. toweri using histology to identify the mechanism of maternal–embryo nutrient transfer. By early‐gestation, embryos have depleted their yolk supplies. Yolks are released into the ovarian lumen and are ingested by the developing embryos, as shown by yolk material in their digestive tracts. The embryonic gut is lined by an epithelium consisting of columnar cells with apical microvilli, providing a means for nutrient absorption. Contrary to statements in the literature, embryos develop minuscule trophotaenial rudiments that extend slightly into the ovarian lumen. These structures are formed of an absorptive epithelium that overlies a vascular stroma, similar to the trophotaeniae of other goodeids. Through late gestation, vitellogenic follicles form and oocytes are discharged into the ovarian lumen, contributing to embryonic nutrition. Thus, histological evidence suggests that embryos chiefly obtain nutrients from ingestion of yolk and maternal secretions released into the ovarian lumen. This function possibly is supplemented by uptake via the small hindgut protrusions and other absorptive surfaces (e.g., the skin and the gill epithelium). Our observations are consistent with two evolutionary interpretations of the hindgut protrusions: (a) that they are rudimentary, evolutionary precursors of trophotaeniae formed by exteriorized hindgut; and (b) that they are vestigial remnants of trophotaeniae that were lost during a switch to a form of matrotrophy involving nutrient ingestion.
Corrosion inhibition of amino acids for 316L stainless steel and synergistic effect of I− ions: Experimental and theoretical studies
Authors: Zhao Rongxuan , Yu Qian , Niu Lin 
Published: August 2021

AbstractThe inhibition effect of amino acids l‐lysine (Lys) and l‐arginine (Arg), which serve as inhibition films for corrosion of 316L stainless steel in 0.5 M NaCl solution, is studied by electrochemical measurements. The adsorption of the inhibitor molecules on the steel surface is studied by Fourier transformed infrared spectroscopy (FTIR) and surface‐enhanced Raman spectroscopy (SERS), accompanied by the characterization of the metal surface by scanning electron microscopy (SEM). All in all, Lys or Arg can obviously restrain the corrosion of 316L steel, while the inhibition efficiency is even higher with the assistance of I− ions. Arg always has better inhibition performance than Lys regardless of the addition of I− ions. FTIR and SERS confirm the adsorption of amino acids on the metal surface; at the same time, the morphology and protection effect of the inhibition films is clearly illustrated via SEM images. Thanks to all experimental measurements as mentioned above and theoretical calculations, a mechanism model is proposed to simulate the corrosion inhibition process of amino acids and the synergistic effect of I− ions on 316L steel.