bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proteomic Profile of Sperm in Infertile Males Reveals Changes in Metabolic Pathways
Authors: Liang Jiaying , Zheng Yichun , Zeng Weihong , Chen Liuqing , Yang Shaofen , Du Peng , Wang Yujiang , Yu Xingsu , Zhang Xiqian 
Published: July 2021

AbstractThe objective of the present study was to investigate the differences in the proteomic profiles of sperm from infertile males with severe oligoasthenoteratozoospermia requiring intracytoplasmic sperm injection (ICSI) and normal control sperm from fertile males. Isobaric tag for relative and absolute quantitation labeling and liquid chromatography–tandem mass spectrometry was performed for identifying proteins in the sperm of infertile and fertile males. Differentially expressed proteins were analyzed via the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases through the Database for Annotation, Visualization, and Integrated Discovery, and protein–protein networks were produced using the Search Tool for Retrieval of Interacting Genes. Immunofluorescence and western blotting verified the differential expression of Y-box-binding protein 1(YBX1), adenylate kinase 1 (AK1), and aconitase 2, mitochondrial (ACO2) proteins. Altogether, 3444 proteins were identified in the sperm of infertile and fertile males, and 938 were differentially expressed between the two groups. Pairwise comparisons revealed that 226 and 712 proteins were significantly upregulated and downregulated in infertile males, respectively. These proteins were significantly enriched in metabolic pathways as per KEGG enrichment analysis. YBX1 expression was upregulated in the sperm heads of patients requiring ICSI treatment, whereas AK1 and ACO2, which are critical enzymes involved in energy metabolism, were downregulated in the sperm tails of the same patients. This result indicates that metabolism may have a crucial role in maintaining normal sperm function. Overall, our results provide insights that will further help in investigating the pathogenic mechanisms of infertility and possible therapeutic strategies.
The importance of Mie resonances in ultra-black dragonfish skin pigment particles
Authors: Lohia Ishaan , Ahearn Samuel , Franjieh Joseph , Di Vece Marcel 
Published: July 2021

AbstractThe ultra-black skin of the deep-sea dragonfish consists of small pigment particles which together provide optimal light absorption to prevent detection from bioluminescent predators or prey. The mechanism of light absorption in these pigment particles resembles the nanophotonic approaches to increase solar cell efficiency via Mie scattering and resonances. In this work, the Mie resonance responses of dragonfish pigment particles were investigated with finite-difference time-domain (FDTD) simulations to elucidate the exact mechanism responsible for the ultra-black skin of the dragonfish. Ellipsoidal pigment particles were found to have superior light absorption over spherical pigment particles. The pigment particles were also shown to exhibit forward scattering, demonstrating an important feature for repeated light absorption in pigment-containing skin layers. Although this work contributes to a deeper understanding of the ultra-back skin of the dragonfish, the nanophotonic mechanisms proposed here are likely more general, and could be applied to photovoltaic light management designs and immunometric detection based on light extinction.
Renegotiations and Renewals of Public Contracts
Authors: Beuve Jean , Saussier Stéphane 
Published: July 2021

AbstractThis paper examines the impact of renegotiations on contract renewals. Using an original dataset of procurement contracts in the French car park sector, we show that there exists an optimal level of renegotiations that positively affects the probability of renewing a contract with the same partner. This result holds only when public authorities have discretionary power during the awarding procedure. Such findings suggest that what is usually interpreted as a sign of weakness – frequent renegotiations – might well be good news that indicates that the contracting parties can make contracts adaptable over time.
Wittgenstein, deflationism and moral entities
Authors: Fairhurst Jordi 
Published: July 2021

AbstractThis paper discusses the meta-ethical implications of Wittgenstein’s later moral philosophy. According to Lovibond and Brandhorst, Wittgenstein provided a novel conception of moral facts, properties and objects by adopting deflationism. Lovibond argues that Wittgenstein’s seamless conception of language together with his non-foundational epistemology and non-transcendent understanding of rationality involves a change of perspective towards a plausible and non-mystificatory moral realism. Meanwhile, Brandhorst argues that Wittgenstein’s provides a deflationist conception of moral truths from which we obtain a deflationist conception of moral facts. This paper argues, on the contrary, that the attribution of deflationism does not do justice to Wittgenstein’s later work. It is concluded, therefore, that the appeal to deflationism does not afford or substantiate the exegetical claims made by Lovibond and Brandhorst.
Investigation of the long-term stability of various tinctures belonging to the lamiaceae family by HPLC and spectrophotometry method
Authors: Sik Beatrix , Hanczné Lakatos Erika , Kapcsándi Viktória , Székelyhidi Rita , Ajtony Zsolt 
Published: July 2021

AbstractThe aim of the current study was to analyze the stability of rosmarinic acid in ethanolic tinctures of lemon balm (Melissa officinalisL.), oregano (Origanum vulgareL.), peppermint (Mentha x piperita), rosemary (Rosmarinus officinalisL.), sage (Salvia officinalisL.), and thyme (Thymus vulgarisL.). High-performance liquid chromatography with diode-array detection (HPLC–DAD) was employed to monitor the concentration of the marker compound over a six month period. Furthermore, the tinctures were also evaluated for caffeic acid, total phenolic content, and 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity. We observed that the concentration of rosmarinic acid in tincture stored in closed amber glasses at ambient temperature decreased significantly during 6-month storage. Furthermore, our study squarely confirms the fact that a part of rosmarinic acid is converted to caffeic acid. The tested tinctures can be listed in the following order according to the greatest stability of the marker compound: rosemary > peppermint > oregano > lemon balm > thyme > sage. The results of the study indicated a linear relationship between DPPH values and total phenolic (R2 = 0.92) or rosmarinic acid (R2 = 0.85) contents.
Multi-fractal characteristics of pore structure for coal during the refined upgrading degassing temperatures
Authors: Wang Jianjun , Liu Lingli , Cui Zehong , Wang Hongjun , Li Teng , Duan Lijiang , Cheng Youyou , Su Penghui , Li Ming , Wei Xiaoyi 
Published: July 2021

AbstractThe low-temperature nitrogen adsorption measurement is commonly used to describe the pore structure of porous medium, while the role of degassing temperature in the low-temperature nitrogen adsorption measurement does not attract enough attention, various degassing temperatures may lead to the different pore structure characterization for the same coal. In this study, the low-rank coal collected from Binchang mining area, southwest of Ordos Basin was launched the low-temperature nitrogen adsorption measurement under seven various degassing temperatures (120 °C, 150 °C, 180 °C, 210 °C, 240 °C, 270 °C and 300 °C), respectively, the dynamic change of the pore structure under refined upgrading degassing temperatures are studied, and it was also quantitative evaluated with the multi-fractal theory. The results show that the pore specific surface area and pore volume decrease linearly with the increased degassing temperatures, ranges from 12.53 to 2.16 m2/g and 0.01539 to 0.00535 cm3/g, respectively. While the average pore aperture features the contrary characteristics (various from 4.9151 to 9.9159 nm), indicating the pore structure has been changed during the refined upgrading degassing temperatures. With the upgrading degassing temperatures, the sizes of hysteresis loop decrease, and the connectivity of pore structure enhanced. The multi-fractal dimension and multi-fractal spectrum could better present the partial abnormal of pore structure during the refined upgrading degassing temperatures, and the quality index, Dq spectrum, D−10–D10 and multi-fractal spectrum could describe the homogeneity and connectivity of the pores finely. The degassing temperatures of 150 °C, 180 °C and 270 °C are selected as three knee points, which can reflect the partial abnormal of the pore structure during the refined upgrading degassing temperatures. Under the lower degassing temperature (< 150 °C), the homogeneity and connectivity of the pore feature a certain increase, following that it presents stable when the degassing temperatures various from 150 to 180 °C. The homogeneity and connectivity of the pore would further enhanced until the degassing temperature reaches to 270 °C. Because of the melting of the pore when the degassing temperature exceeds 270 °C, the complexity of pore structure increased. In this study, we advise the degassing temperature for low-temperature nitrogen adsorption measurement of low-rank coal should not exceed 120 °C.
Hybrid Model Based on ReliefF Algorithm and K-Nearest Neighbor for Erythemato-Squamous Diseases Forecasting
Authors: Alotaibi Abdullah S. 
Published: July 2021

AbstractMachine learning (ML) techniques have been used to solve real-world problems for decades. In the field of medical sciences, these approaches have been found to be useful in the diagnosis and prognosis of a variety of medical disorders. However, when dealing with voluminous, inconsistent, and higher-dimensional data, conventional ML approaches have failed to deliver the expected results. Researchers have suggested hybrid solutions to resolve these problems, which have been found to be more effective than conventional methods because these systems integrate their merits while reducing their drawbacks. In the current research article, hybrid model has been presented by coupling feature optimization with prediction approach. The proposed hybrid model has two stages: the first involves implementing the ReliefF Algorithm for optimum feature selection in erythemato-squamous diseases, and the second involves implementing k-nearest neighbor (KNN) for prediction of those selected optimum features. The experimentation was carried out on bench mark dataset for erythemato-squamous diseases. The presented hybrid model was also assessed with conventional KNN approach based on various metrics such as classification accuracy, kappa coefficient, recall, precision, and f-score.
Evolutionary and taphonomic implications of a new species ofAmphoracrinusfrom the early Viséan of Kentucky
Authors: Ausich William I. , Koenig Steven C. , Goldstein Alan , Monreal Gretel 
Published: July 2021

AbstractThe youngest species ofAmphoracrinus,A. tenaxnew species, is described from the Muldraugh Member of the Borden Formation (early Viséan) of north-central Kentucky. With this new occurrence, both the oldest and youngest named species ofAmphoracrinusare from North America. Numerous Tournaisian and Viséan crinoid faunas are documented in the United States, but only four are known to containAmphoracrinus. Morphological analysis indicates thatA. tenaxis more closely aligned with species from China than with species from Western Europe or other species from North America, whereAmphoracrinuswas most diverse and abundant, which has implications for understanding paleogeographic dispersal. The holotype ofA. tenaxwas partially disarticulated on the seafloor before burial, and final burial occurred early during disarticulation. The relative state of disarticulation from pinnules to columnals suggests that plates bound only with ligaments disarticulated as a function of surface area of ligaments binding an articulation.UUID:http//zoobank.org/c7faf06e-bdd1-43a2-8c10-1364a0aeae0d
Height–diameter allometry in African monodominant forest close to mixed forest
Authors: Loubota Panzou Grace Jopaul , Bocko Yannick Enock , Mavoungou Alain Yves , Loumeto Jean-Joël 
Published: July 2021

AbstractAfrican monodominant forests are frequently formed byGilbertiodendron dewevrei(De Wild.) J. Leonard and commonly found close to mixed forests. However, previous studies have ignored differences between these two forest types in height–diameter allometry, which is extremely important for aboveground biomass (AGB) estimates. This study aims to evaluate the performance of height–diameter models and their effects on height attributes and AGB estimations in African monodominant and mixed forests. Four 1-ha plots divided in 16 subplots (0.25 ha) were installed in each forest type in northern Republic of Congo. We measured diameter of all trees ≥ 10 cm diameter for each subplot and we measured the height of 264 trees over a large range of 7–64 m in two forest types. There was a significant difference in height–diameter allometry between two forest types and trees were taller and had greater AGB in monodominant forests than in mixed forests. Two height–diameter models from the literature generated the lowest error values when predicting tree height and AGB in mixed forests, whereas no model derived from the literature was appropriate for monodominant forests. The variation in height–diameter allometry between monodominant and mixed forests influences AGB estimates that have practical implications for carbon monitoring.
AIDS-related deaths in Turkey between 2009 and 2018
Authors: Teker Ayse Gulsen 
Published: July 2021

Abstract
The prevalence of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) is increasing day by day in the region, including Turkey. The study aimed to examine AIDS-related deaths in Turkey between 2009 and 2018 according to the national death registration system records. In this descriptive study, data on AIDS-related deaths were obtained from the Turkish Statistical Institute. The data consist of the cause of death codes, year of death, age and gender. Findings were presented using numbers and percentages. Seven hundred twenty-one AIDS-related deaths were reported in Turkey between 2009 and 2018. AIDS-related deaths in Turkey increased more than twice at the end of 10 years. The male/female death ratio is 4.5. Deaths under the age of 15 were 4.2% in total; however, they were increased to 10.2% in 2018. AIDS-related deaths are decreasing in the world but increasing in Turkey. The data from the Ministry of Health do not match the data of the national death registration system. Establishing a strong and accurate HIV/AIDS reporting system and identifying the causes and risk groups of this increase in AIDS-related deaths are critical.
Within-person changes in basal cortisol and caregiving modulate executive attention across infancy
Authors: Brandes-Aitken Annie , Braren Stephen , Vogel Sarah C. , Perry Rosemarie E. , Brito Natalie H. , Blair Clancy 
Published: July 2021

AbstractOne pathway by which environments of socioeconomic risk are thought to affect cognitive development is through stress physiology. The biological systems underpinning stress and attention undergo a sensitive period of development during infancy. Psychobiological theory emphasizes a dynamic pattern of context-dependent development, however, research has yet to examine how basal cortisol and attention dynamically covary across infancy in ecologically valid contexts. Thus, to address these gaps, we leveraged longitudinal, multilevel analytic methods to disentangle between- from within-person associations of hypothalamic–pituitary–adrenal (HPA) axis activity and executive attention behaviors across infancy. We use data from a large longitudinal sample (N = 1,292) of infants in predominantly low-income, nonurban communities at 7-, 15-, and 24-months of age. Using multilevel models, we investigated longitudinal associations of infant attention and basal cortisol levels and examined caregiving behaviors as moderators of this relationship. Results indicated a negative between- and within-person association between attention and cortisol across infancy and a within-person moderation by caregiver responsiveness. In other words, on the within-person level, higher levels of cortisol were concomitantly associated with lower infant attention across the first 2 years of life. However, variation in the caregiver's level of responsiveness either buffered or sensitized the executive attention system to the negative effects of physiological stress.
How to design co-programs
Authors: GIBBONS JEREMY 
Published: July 2021

Abstract
The observation that program structure follows data structure is a key lesson in introductory programming: good hints for possible program designs can be found by considering the structure of the data concerned. In particular, this lesson is a core message of the influential textbook “How to Design Programs” by Felleisen, Findler, Flatt, and Krishnamurthi. However, that book discusses using only the structure of input data for guiding program design, typically leading towards structurally recursive programs. We argue that novice programmers should also be taught to consider the structure of output data, leading them also towards structurally corecursive programs.
PhD Abstracts
Authors: HUTTON GRAHAM 
Published: July 2021

Many students complete PhDs in functional programming each year. As a service to the community, twice per year the Journal of Functional Programming publishes the abstracts from PhD dissertations completed during the previous year.
The abstracts are made freely available on the JFP website, i.e. not behind any paywall. They do not require any transfer of copyright, merely a license from the author. A dissertation is eligible for inclusion if parts of it have or could have appeared in JFP, that is, if it is in the general area of functional programming. The abstracts are not reviewed.
Identification of palliative care needs in hemodialysis patients: An update
Authors: Liem Ylian Serina , Eidemak Inge , Larsen Sille , Sjøgren Per , Molsted Stig , Sørensen Jonas , Laursen Louise , Kurita Geana Paula 
Published: July 2021

AbstractObjectiveEnd-stage kidney disease and hemodialysis (HD) treatment are associated with a high symptom burden in many patients. This study aimed at updating patient-reported outcomes concerning quality of life, fatigue, anxiety, and depression in HD patients treated in a single center in order to assess the need for palliative care provision.MethodA cross-sectional design, in which a sample of patients treated at a single HD department (Rigshospitalet, Denmark) between January and June 2019, was analyzed using the Kidney Disease Quality of Life Short Form, the Multidimensional Fatigue Inventory, and the Hospital Anxiety and Depression Scale. In addition, we compared the results with previously published data from the same department (2000) and with an age- and sex-matched sample from the Danish general population (1997/2014). Chi-square and t-tests were used for comparisons.ResultsScreened patients = 242, included = 141, analyzed = 131 (70.2% male, mean age = 61.3 years). HD patients reported low scores for quality of life, high scores for fatigue, and approximately 30% had anxiety/depression. Regarding quality of life, they had significantly lower scores on general health (P ≤ 0.000), vitality (P = 0.009), social functioning (P = 0.001), mental health (P = 0.007), and mental component (P = 0.005) compared with former data of HD patients. Moreover, they reported significantly poorer quality of life and worse fatigue compared with the general Danish population.Significance of resultsIn the patients undergoing HD, quality of life was poor and worsened when compared with former HD patients’ data. Additionally, fatigue, depression, and anxiety in HD patients were prevalent. A clear need for palliative care provision was observed.
Ethno-Religious Identification and Support for Interreligious Violence: A Study of Muslim and Christian Students in Indonesia and the Philippines
Authors: Kanas Agnieszka , Scheepers Peer , Sterkens Carl 
Published: July 2021

AbstractThis study examines mechanisms and conditions under which ethnoreligious identification is related to support for out-group violence. It uses unique survey data collected among religious minorities and majorities in conflict and non-conflict regions in Indonesia and the Philippines. We find that strong ethno-religious identification is positively related to support for out-group violence. This relationship is fully mediated by the perception of out-group threat, suggesting that ethno-religious identification facilitates the perception of out-group threat, which, in turn, is positively related to support of violence. While the experience of communal violence increases support for interreligious violence, it does not influence the relationship between perceived group threat and support for violence. Interestingly, there is some evidence that the negative influence of intergroup contact on violence support is weaker for those who experienced communal violence.
Design of wideband multi-layer quadrature hybrid couplers with butterfly shaped resonators
Authors: Yayan Meliksah , Yapici Alparslan Cagri 
Published: July 2021

AbstractIn this paper, a wideband quadrature hybrid coupler is presented. The proposed structure has a multi-layer microstrip topology. In this topology, there are three substrate layers including prepreg material and four conductive layers. In order to achieve equal power division between through and coupled arms of the directional coupler while maintaining a 90° phase shift, aperture coupling between the resonators located at both top and bottom layers is utilized. So as to avoid any unwanted effects of prepreg material in such multilayer topology, via shielding around resonators are inserted. In this study, coupling from input ports to output ports is accomplished by the shielded butterfly shaped slot etched to the ground layer of top and bottom layers. The proposed design operates within 3–12 GHz. The acquired phase imbalance between the coupled ports is <±2.5°. The results of the manufactured quadrature hybrid coupler agree well with the simulated results.
Gravel Parameterization Schemes and its Regional Assessment on Tibetan Plateau Using RegCM4
Authors: Liu Yigang , Lyu Shihua , Ma Cuili , Xu Yue , Luo Jiangxin 
Published: July 2021

AbstractIn this study, the impact of gravel was taken into account in the regional climate model version 4.7, which was driven by the ERA‐Interim with a resolution of 1.5 km in this numerical experiment. The gravel parameterization schemes and the original soil hydrothermal parameterization schemes were used in the regional soil hydrothermal simulations on the Tibetan Plateau (TP), respectively. The performance of the two schemes in simulating the soil moisture (SM) was assessed. Moreover, three areas were selected in terms of the distribution of gravel content on the TP to investigate the differences in the internal mechanism of the model between the two schemes. The performance of the gravel schemes in simulating SM is generally improved compared with that of the original schemes. The simulation effect is superior in the southeastern TP. Except for the southeastern TP, the performance in simulating the temporal variations of SM below the soil depth of 1.0 m still needs to be improved. The fractional saturated area (fsat) and the fraction of the inundated area (fh2osfc) are two pivotal variables that control the important component of the hydrologic process. There may be a threshold for the increase of fh2osfc, when the increase of fh2osfc is lower than this value, the main effect of increasing fh2osfc is to reduce the surface moisture that is, divided into the input of soil. However, when the increase of fh2osfc is higher than this value, the main effect of increasing fh2osfc is to increase the bottom drainage from the surface water store. The increasing gravel content will induce the decreasing mineral soil saturated hydraulic conductivity, which leads to SM increases, the opposite is true.