bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fransiska Keron Ola HUBUNGAN PENGETAHUAN TERHADAP MOTIVASI DALAM MENCUCI TANGAN DALAM PENANGGULANGAN COVID-19 DI ERA PANDEMI
Authors: Ola Fransiska 
Published: June 2021

HUBUNGAN PENGETAHUAN TERHADAP MOTIVASI DALAM MENCUCI TANGAN DALAM PENANGGULANGAN COVID-19 DI ERA PANDEMI

Fransiska Keron Ola

Sekolah Tinggi Ilmu Kesehatan Dirgahayu Samarindae-mail: cerollao@gmail.com

ABSTRACT

Latar Belakang: Pandemi Covid-19 melanda Indonesia sejak bulan Maret 2020 dan di seluruh dunia. Dampak Pandemik Covid-19 sudah di lakukan pemerintah dan seluruh elemen masyarakat. Sangat di harapkan masyarakat berperan aktif dalam penanggulangan pencegahan covid-19 dengan cara menggunakan masker, menjaga jarak, mencuci tangan dengan baik dan benar di bawah air mengair serta melakukan social dictancing dengan cara menjauhi kerumunan dan menjaga jarak. Tujuan : Membahas pengetahuan terhadap motifasi mencuci tangan di dalam kehidupan sehari-hari. Metode:Penelitian kuantitatif dengan pendekatan cross sectional. Rancangan penelitian adalah survey analitik dengan cara penyebaran kuisioner melalui online dengan media Whatshap grup. Pengambilan sampel penelitian dengan cara total sampling. Pengolahan data menggunakan analisis korelasi spearman rank. Hasil : Hasil perhitungan distribusi pengetahuan mencuci tanngan 100% tidak baik, motifasi mencuci tangan 100% tidak pernah di lakukan. Hasil pengujian koefisien korelasi spearman rank 0,00 dengan kooefisien tingkat hubungan sangat rendah Kesimpulan: Kesimpulan dari penelitian adalah tidak ada hubungan antara pengetahuan terhadap motivasi mencuci tangan di dalam di kampus X Kota Samarinda dalam penanggulan Covid-19 di Era Pandemic.

Key Words: Pengetahuan, Motivasi, Mencuci Tangan, Covid-19, Era Pandemi
A Vector Autoregressive Market Model for IT Sector Stocks in India
Authors: Dash Mihir , S. Rita 
Published: June 2021

This study proposes a vector autoregressive form for the market model and tests its significance against the market model for information technology (IT) sector stocks in the Indian stock market. The analysis was performed for a sample of nineteen IT sector stocks listed on the National Stock Exchange of India, of which nine stocks were large-cap, six were mid-cap, and four were small-cap. The study period considered was Jan. 1, 2018 – Dec. 31, 2018. The key contribution of the study was the finding that the vector autoregressive model is a better model of stock returns than the market model for IT sector stocks. Thus, IT sector stocks seem to react more to market movements from the previous day than on the day itself. The implication for asset pricing modelling is that systematic risk may be further decomposed into a component corresponding to sensitivity to market movements on the day and a component corresponding to sensitivity to market movements on the previous day. The asset pricing model would be extended to include market risk premia for both of these components of systemic risk. Keywords: market model, vector autoregressive model, IT sector, asset pricing modelling, systematic risk.
History of Banking in Sudan (Conventional and Islamic): A Critical Review (1903-2019)
Authors: Mustafa Omer Allagabo Omer 
Published: June 2021

This paper critically reviews the developmental stages of banking (Conventional and Islamic) in Sudan throughout the last 115 years (1903-2019). Historical and descriptive-analytical approaches were used. Historical data collected from the annual reports of The Central Bank of Sudan and relevant studies were used to describe and compare stages during that period. The results indicated that political instability and ideology changes of the state (e.g., Colonialism, independence and democracy, socialism and Islamic) systems played a significant role in the formation of stages of development of Sudan’s banking systems (e.g., conventional, Islamic, dual system). Moreover, the implementation of the Islamic Sharia Law in 1983 was the original basis for the augmentation of the Islamization of the country’s banking system, particularly as it pertained to the prohibition of charging interest. Under the Comprehensive Peace Agreement (CPA: 2005-2010), the conventional banking (interest rate) in Southern Sudan was restored, whereas the Islamic approach continued in the north. Notwithstanding, all banks were managed by one central bank in the north namely The Central Bank of Sudan. The study highlights the relationship between factors affecting political stability and the growth of stability and the banking system.
Prólogo
Authors: Hooker Blandford Alta Suzzane 
Published: June 2021

Este volumen No. 28, presenta una compilación estructurada en 5 secciones, las cuales comprenden 13 artículos; tres en el área de Educación, tres en Salud, Uno en Genero e Interculturalidad, tres en Ciencias Sociales y tres en Agropecuaria.Los resultados de estas investigaciones aportan significativamente a la praxis innovadora de la comunidad universitaria, y constituyen un medio educativo y de comunicación para compartir con la comunidad de profesores, investigadores y estudiantes del mundo académico, en una expresión crítica, autónoma y de emancipación en un ambiente de ciudadanías interculturales de género.
Public Perceptions of the Canadian Government’s Initial Response to Coronavirus: A Canadian Broadcasting Company Content Analysis
Authors: Munroe-Lynds Cora-Lynn 
Published: June 2021

It is crucial for the government to maintain the public’s trust during uncertain risk. The Canadian government had approximately three months to develop a risk management strategy before Canada saw its first case of coronavirus. This study aims to show how the Canadian Broadcasting Company (CBC) portrays government decision making during the initial outbreak of Coronavirus in January 2020 through March 2020 exclusive by examining 10 articles per month. Over the course of the last three months, government officials were increasingly cited in the CBC news articles. Results from this study shows that as the condition in Canada worsened, more evidence-based decision making is present in the articles, especially during the month of March.
Hemin Covalently Functionalized Carbon Nanobranch with Enzyme‐Like and Photocatalytic Activities for Synergistic Dye Degradation and Antibacterial Therapy
Authors: Xu Chengjie , Zhou Li , Zheng Sidi , Yu Deshuai , Tang Yonghua , Fan Chaoyu , Lin Changxu , Zhou Dongfang , Lin Youhui 
Published: June 2021

AbstractThe development of artificial enzymes with excellent enzyme‐like activities and unique features is highly desirable for their practical applications. Herein, a one‐pot facile method to synthesize hemin covalently functionalized carbon nanobranch (CN‐hemin) via direct pyrolysis of citric acid and covalent coupling of hemin to the formed carbon skeleton, is reported. This strategy is reasonably straightforward, cheap, and environmentally friendly, without any extraneous oxidant, reductant, and harmful additives during the preparation process. Furthermore, the obtained dendritic hybrids possess good water‐solubility, intrinsic peroxidase‐like activity, and satisfactory photocatalytic performance in visible light. These extraordinary properties are mainly due to the structure of CN‐hemin which contains iron porphyrin, aromatic carbon, and citric acid residues. Most importantly, under visible light irradiation, the as‐prepared hemin‐incorporated nanohybrid can act as robust agents for synergistic dye degradation and antibacterial therapy toward Staphylococcus aureus and methicillin‐resistant S. aureus. It is expected that this study can shed valuable light on developing advanced multifunctional nanozymes with combined favorable properties for highly efficient elimination of environmental pollutants and antibacterial treatment.
Efficient Thermally Evaporated γ‐CsPbI3 Perovskite Solar Cells
Authors: Zhang Zongbao , Ji Ran , Kroll Martin , Hofstetter Yvonne J. , Jia Xiangkun , Becker‐Koch David , Paulus Fabian , Löffler Markus , Nehm Frederik , Leo Karl , Vaynzof Yana 
Published: June 2021

AbstractThin‐film deposition by thermal evaporation offers many advantages, yet in the field of perovskite photovoltaics solution‐processed devices significantly outperform those fabricated by thermal evaporation. Here, high‐quality γ‐CsPbI3 perovskite layers by coevaporation of PbI2 and CsI with a small amount of phenylethylammonium iodide (PEAI) are deposited. It is demonstrated that the addition of PEAI into the perovskite layers leads to a preferred crystal orientation and a far improved microstructure, with columnar domains that protrude throughout the film's thickness. This is accompanied by a reduced density of defects as evidenced by the increase in photoluminescence and decrease in Urbach energy as compared to reference CsPbI3 films. Photovoltaic devices based on the PEAI containing perovskite layers reach up to 15% in power conversion efficiency, thus surpassing not only the performance of reference CsPbI3 devices, but also that of most solution‐processed PEAI containing inorganic CsPbX3 (X = Cl, Br, I) perovskite solar cells. Importantly, encapsulated thermally evaporated perovskite devices maintain their performance for over 215 days, demonstrating the stabilizing effect of PEAI on thermally evaporated CsPbI3.
Beyond faith: Biomolecular evidence for changing urban economies in multi‐faith medieval Portugal
Authors: Toso Alice , Schifano Simona , Oxborough Charlotte , McGrath Krista , Spindler Luke , Castro Anabela , Evangelista Lucy , Filipe Vanessa , Gonçalves Maria José , Marques Antonio , Mendes da Silva Inês , Santos Raquel , Valente Maria João , McCleery Iona , Alexander Michelle 
Published: June 2021

AbstractObjectivesDuring the Middle Ages, Portugal witnessed unprecedented socioeconomic and religious changes under transitioning religious political rule. The implications of changing ruling powers for urban food systems and individual diets in medieval Portugal is poorly understood. This study aimed to elucidate the dietary impact of the Islamic and Christian conquests.Materials and MethodsRadiocarbon dating, peptide mass fingerprinting (ZooMS) and stable isotope analysis (δ13C, δ15N) of animal (n = 59) and human skeletal remains (n = 205) from Muslim and Christian burials were used to characterize the diet of a large historical sample from Portugal. A Bayesian stable isotope mixing model (BSIMM) was used to estimate the contribution of marine protein to human diet.ResultsEarly medieval (8–12th century), preconquest urban Muslim populations had mean (±1SD) values of −18.8 ± 0.4 ‰ for δ13C 10.4 ± 1 ‰ for δ15N, indicating a predominantly terrestrial diet, while late medieval (12–14th century) postconquest Muslim and Christian populations showed a greater reliance on marine resources with mean (±1SD) values of −17.9 ± 1.3‰ for δ13C and 11.1 ± 1.1‰ for δ15N. BSIMM estimation supported a significant increase in the contribution of marine resources to human diet.DiscussionThe results provide the first biomolecular evidence for a dietary revolution that is not evidenced in contemporaneous historical accounts. We find that society transitioned from a largely agro‐pastoral economy under Islamic rule to one characterized by a new focus on marine resources under later Christian rule. This economic change led to the naissance of the marine economy that went on to characterize the early‐modern period in Portugal and its global expansion.
Electrolyte Chemistry Towards Improved Cycling Stability in Na‐Based Dual‐Ion Batteries with High‐Power/Energy Storage
Authors: Hou Xian‐Kun , Li Shao‐Fang , Li Wen‐Hao , Liang Hao‐Jie , Gu Zhen‐Yi , Luo Xiao‐Xi , Wu Xing‐Long 
Published: June 2021

AbstractDual‐ion batteries (DIBs) have attracted great research interests owing to the co‐utilization of cation and anion as charge carriers. Unlike the low energy density (Eden) of supercapacitors and halogen‐ion batteries also with anion working, graphite‐cathode‐based DIBs exhibit obviously higher Eden with high working voltage. However, general electrolytes cannot satisfy the high‐energy demand for Na‐based DIBs with high power density. Herein, we design an effective electrolyte with optimized performance to limit the occurrence of side reactions during cycling, improving the cycling stability and Eden of Na‐based DIBs. Such electrolyte‐modified Na‐DIBs exhibit higher discharge plateau and specific capacity compared to the pristine batteries, contribute preeminent Eden of 370.4 Wh/kg at a high‐power density of 8888.4 W/kg (2.0 A/g), and deliver higher capacity retention of 72 % after 1000 cycles under 40 °C (1.0 A/g). All of these improvements are attributed to the interphase protection of anode/cathode by modified electrolyte, and the increase of diffusion ability under high potential. This strategy not only provides reference significance for enhancing the performance of DIBs, but also promotes the development of DIBs with high‐power/energy and long‐term cycle working condition.
Community college faculty connections with geoscience societies: Community engagement and leadership development
Authors: Tvelia Sean , Branlund Joy , Hams Jacquelyn , Baer Eric M. D. , Layou Karen M. , Macdonald R. Heather 
Published: June 2021

AbstractThis chapter addresses the engagement of geoscience societies with community college faculty, traces the emergence of the Geo2YC Division as a model for others, and provides examples that focus on ways to build a professional community.
Collaborative research on carbon reinforced concrete structures in the CRC/TRR 280 project
Authors: Beckmann Birgit , Bielak Jan , Bosbach Sven , Scheerer Silke , Schmidt Christopher , Hegger Josef , Curbach Manfred 
Published: June 2021

AbstractNew materials allow new building designs and construction types. However, initial construction projects using the new materials show that traditional construction principles ‐ in the case of carbon reinforced concrete those derived from steel reinforced concrete ‐ are still being used. In other words, conventional materials are merely substituted. Only combined with intelligent construction strategies it is possible to exploit the full potential of innovative materials. Detached from established patterns of thought, the fundamentals for a new way of building with concrete are to be created in the frame of the Collaborative Research Centre Transregio (CRC/TRR) 280 project “Design Strategies for Material‐Minimised Carbon Reinforced Concrete Structures–Principles of a New Approach to Construction” at Technische Universität Dresden (TUD) and RWTH Aachen University. These are to be based on profound insights into the mechanical behavior of novel mineral structures. Innovative lightweight construction strategies and material composites reduce resource and energy consumption while maintaining high levels of usability, structural safety, and durability, while the aspirational esthetics make a valuable contribution to the culture of building. The long‐term research alliance of TUD and RWTH pools the excellent competencies, inspiring research into material‐minimized construction with mineral composites. The article highlights the research activities planned for the first period from July 2020 to June 2024.
Atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma: Early clinical experience
Authors: Hiraoka Atsushi , Kumada Takashi , Tada Toshifumi , Hirooka Masashi , Kariyama Kazuya , Tani Joji , Atsukawa Masanori , Takaguchi Koichi , Itobayashi Ei , Fukunishi Shinya , Tsuji Kunihiko , Ishikawa Toru , Tajiri Kazuto , Ochi Hironori , Yasuda Satoshi , Toyoda Hidenori , Ogawa Chikara , Nishimura Takashi , Hatanaka Takeshi , Ohama Hideko , Nouso Kazuhiro , Morishita Asahiro , Tsutsui Akemi , Nagano Takuya , Itokawa Norio , Okubo Tomomi , Arai Taeang , Imai Michitaka , Koizumi Yohei , Nakamura Shinichiro , Joko Kouji , Iijima Hiroko , Hiasa Yoichi , Kudo Masatoshi ,   Real‐life Practice Experts for HCC (RELPEC) Study Group, and HCC 48 Group (Hepatocellular Carcinoma Experts from 48 Clinics in Japan)
Published: June 2021

AbstractBackgroundAlthough atezolizumab plus bevacizumab (Atez/bev) treatment has been developed for unresectable hepatocellular carcinoma (u‐HCC), changes in hepatic function during therapy have yet to be reported.AimThis retrospective clinical study aimed to elucidate early responses to Atez/Bev.MethodsFrom September 2020 to April 2021, 171 u‐HCC patients undergoing Atez/Bev treatment were enrolled (BCLC stage A:B:C:D = 5:68:96:2). Of those, 75 had no prior history of systemic treatment. Relative changes in hepatic function and therapeutic response were assessed using albumin‐bilirubin (ALBI) score and Response Evaluation Criteria in Solid Tumors (RECIST), ver. 1.1, respectively.ResultsIn initial imaging examination findings, objective response rates for early tumor shrinkage and disease control after 6 weeks (ORR‐6W/DCR‐6W) were 10.6%/79.6%. Similar response results were observed in patients with and without a past history of systemic treatment (ORR‐6W/DCR‐6W = 9.7%/77.8% and 12.2%/82.9%), as well as patients in whom Atez/Bev was used as post‐progression treatment following lenvatinib (ORR‐6W/DCR‐6W = 7.7%/79.5%), for which no known effective post‐progression treatment has been established. In 111 patients who underwent a 6‐week observation period, ALBI score was significantly worsened at 3 weeks after introducing Atez/Bev (−2.525 ± 0.419 vs −2.323 ± 0.445, p < .001), but then recovered at 6‐weeks (−2.403 ± 0.452) as compared to 3‐weeks (p = .001). During the observation period, the most common adverse events were appetite loss (all grades) (12.3%), general fatigue/hypertension (all grades) (11.1%, respectively), and urine protein (all grades) (10.5%).ConclusionAtez/Bev might have therapeutic potential not only as first but also later‐line treatment of existing molecular target agents. In addition, this drug combination may have less influence on hepatic function during the early period, as the present patients showed a good initial therapeutic response.
Effect of SLCO1B1 T521C on Statin‐Related Myotoxicity With Use of Lovastatin and Atorvastatin
Authors: Lu Brian , Sun Laura , Seraydarian Manuel , Hoffmann Thomas J. , Medina Marisa W. , Risch Neil , Iribarren Carlos , Krauss Ronald M. , Oni‐Orisan Akinyemi 
Published: June 2021

The association between the c.521T>C variant allele in SLCO1B1 (reference single nucleotide polymorphism (rs)4149056) and simvastatin‐induced myotoxicity was discovered over a decade ago; however, whether this relationship represents a class effect is still not fully known. The aim of this study was to investigate the relationship between rs4149056 genotype and statin‐induced myotoxicity in patients taking atorvastatin and lovastatin. Study participants were from the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort. A total of 233 statin‐induced myopathy + rhabdomyolysis cases met the criteria for inclusion and were matched to 2,342 controls. To validate the drug response phenotype, we replicated the previously established association between rs4149056 genotype and simvastatin‐induced myotoxicity. In particular, compared with homozygous T allele carriers, there was a significantly increased risk of simvastatin‐induced myopathy + rhabdomyolysis in homozygous carriers of the C allele (CC vs. TT, odds ratio [OR] 4.62, 95% confidence interval [CI] 1.58–11.90, P = 0.003). For lovastatin users, homozygous carriers of the C allele were also at increased risk of statin‐induced myopathy + rhabdomyolysis (CC vs. TT, OR 4.49, 95% CI 1.68–10.80, P = 0.001). In atorvastatin users, homozygous carriers of the C allele were twice as likely to experience statin‐induced myopathy, though this association did not achieve statistical significance (CC vs. TT, OR 2.00, 95% CI 0.44–6.59, P = 0.30). In summary, our findings suggest that the association of rs4149056 with simvastatin‐related myotoxicity may also extend to lovastatin. More data is needed to determine the extent of the association in atorvastatin users. Altogether, these data expand the evidence base for informing guidelines of pharmacogenetic‐based statin prescribing practices.
Influence of study discontinuation during the run‐in period on the estimated efficacy of sacubitril/valsartan in the PARAGON‐HF trial
Authors: Suzuki Kota , Claggett Brian , Minamisawa Masatoshi , Packer Milton , Zile Michael R. , Pfeffer Marc A. , Chiang Lu‐May , Lefkowitz Martin , McMurray John J.V. , Solomon Scott D. , Desai Akshay S. 
Published: June 2021

AbstractAimsThe 4822 patients randomized in the PARAGON‐HF trial were a subset of 5746 initially eligible patients who entered sequential run‐in periods. We identified patient factors associated with study discontinuation during the run‐in period and estimated the implications of these discontinuations for the overall study result.Methods and resultsWe utilized multivariable logistic regression models to identify patient factors associated with study discontinuation during the run‐in period. The efficacy of sacubitril/valsartan in a broader cohort approximating the full run‐in population was estimated by weighting randomized patients according to the inverse probability of run‐in completion. A total of 924 (16.1%) subjects failed to complete the run‐in period. In multivariable models, non‐completion was associated with region other than Central Europe, lower systolic blood pressure, lower serum sodium, lower haemoglobin, lower estimated glomerular filtration rate, higher N‐terminal pro‐B‐type natriuretic peptide, higher New York Heart Association functional class, prior heart failure (HF) hospitalization, and lack of prior use of renin–angiotensin system inhibitors or beta‐blocker. In repeat analysis of the effect of randomized treatment in PARAGON‐HF giving greater weight to participants resembling those who failed to complete the run‐in period, the incidence of HF hospitalizations and cardiovascular death was higher, and sacubitril/valsartan treatment reduced the composite of total HF hospitalizations and cardiovascular death compared with valsartan (rate ratio 0.86; 95% confidence interval 0.74–1.00).ConclusionPatients with more advanced HF were at higher risk for non‐completion of the run‐in period in PARAGON‐HF. Re‐analysis of study outcomes accounting for the effect of run‐in non‐completion did not alter the estimated treatment effects of sacubitril/valsartan vs. valsartan.
Loc680254 regulates Schwann cell proliferation through Psrc1 and Ska1 as a microRNA sponge following sciatic nerve injury
Authors: Yao Chun , Wang Qihui , Wang Yaxian , Wu Jiancheng , Cao Xuemin , Lu Yan , Chen Yanping , Feng Wei , Gu Xiaosong , Dun Xin‐Peng , Yu Bin 
Published: June 2021

AbstractPeripheral nerve injury triggers sequential phenotype alterations in Schwann cells, which are critical for axonal regeneration. Long noncoding RNAs (lncRNAs) are long transcripts without obvious coding potential. It has been reported that lncRNAs participate in diverse biological processes and diseases. However, the role of lncRNA in Schwann cells and peripheral nerve regeneration is unclear. Here, we identified an lncRNA, loc680254, which is upregulated in rat sciatic nerve after peripheral nerve injury. The loc680254 knockdown inhibits Schwann cell proliferation, enhances apoptosis, and hinders cell cycle, while loc680254 overexpression has the opposite effect. Mechanically, we found that loc680254 might act as a microRNA sponge to regulate the expression of mitosis‐related gene, spindle and kinetochore associated complex subunit 1 (Ska1) and proline/serine‐rich coiled‐coil 1 (Psrc1). Silencing of Psrc1 or Ska1 attenuates the effect of loc680254 overexpression on Schwann cell proliferation. Finally, we repaired the rat sciatic nerve gap with chitosan scaffolds loaded with loc680254‐overexpressing Schwann cells and evaluated axon regeneration and functional recovery. Our results indicated that loc680254 is a new potential modulator for Schwann cell proliferation, which could be targeted to develop novel therapeutic strategies for peripheral nerve repair.