bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neonatal aquatic physiotherapy in neonatal intensive care units: A scoping review
Authors: Aranha V.P. , Chahal A. , Bhardwaj A.K. 
Published: October 2021

BACKGROUND: Therapeutic benefits of neonates undergoing neonatal aquatic physiotherapy (NAPT) are evident from the available literature. However complied report on NAPT is not yet available. Hence, we have mapped the available interventions to treat neonates admitted in neonatal intensive care units (NICUs) using NAPT in a scoping review. METHOD: Six databases which includes, MEDLINE/PubMed, SCOPUS, PEDro, CINHAL, EBSCO and Cochrane were searched with predefined keywords specific to or related to NAPT interventions from 1983 to August, 2020 for the full-text English language articles. RESULTS: A total of 6163 relevant articles were identified from the search process. After duplicates were removed, 6146 articles were screened for inclusion, leaving 809 articles assessed for eligibility criteria. Six (n = 6) articles met all criteria and were included in the final qualitative synthesis. CONCLUSION: NAPT may be an effective intervention to normalize the muscle tone, to promote active movements, postural organization, improves sleep pattern and quality, promotes the thermal and cardiorespiratory adaptations, and moreover reduces neonatal pain among the neonates admitted in NICUs.
Factores que influyen en la cobertura de atención de parto institucional en el hospital básico de San Gabriel en mujeres que durante su periodo de gestación acudieron a los controles prenatales en las unidades operativas rurales del área 2 de la provincia del Carchi durante el periodo enero a noviembre del 2011
Authors: Ledesma Nuñez Erika Yolanda , Montenegro Madroñero Carol Andrea 
Published: October 2021

La maternidad segura es un componente esencial de la salud reproductiva, principalmente porque el embarazo y parto son causas significativas de discapacidad y muerte de mujeres, que viven en países en vías de desarrollo. Es por esto que la presente investigación tiene coma finalidad conocer los factores que influyen en la cobertura de parto institucional del hospital Básico de San Gabriel, aplicándose coma técnica la encuesta a las madres que acuden a las diferentes Unidades Operativas Rurales del Írea 2, donde se comprobó que existen factores determinantes para que las mujeres en estado de gestación no acudan al momento del parto al hospital de referencia.
Durante la investigación realizada se evidencio que el índice de atención de partos de pacientes referidas de las Unidades Operativas Rurales es del 2.43%, razón por la cual fue motivo de realizar este estudio, el mismo que presenta el análisis de la interrelación entre factores individuales como predictores de la atención prenatal y parto institucional. Se hipotetiza que la atención materna, además de estar correlacionada con factores individuales como la educación de la madre, tiene estrecha relación con la disponibilidad y la calidad de atención de los servicios de salud.
En este contexto, los factores influyen significativamente para que las mujeres tengan atención prenatal y parto institucional y así tener una maternidad segura y saludable.
Conocimientos, actitudes y practicas sobre enfermedades inmuno- prevenibles por vacunación en madres de niños menores de dos años que acuden al Centro de Salud Abdón Calderón de la Ciudad de Nueva Loja de Mayo a Diciembre del 2011.
Authors: Padilla Yépez Gabriela Nathaly 
Published: October 2021

El déficit de conocimientos en madres de niños menores de dos arias sobré enfermedades inmuno-prevenibles por vacunación afectan la calidad de vida del nitro, por tal motivo se ha vista la necesidad de realizar esta investigación, utilizando diferentes técnicas para obtener información coma: la observación y encuesta a madres de niños menores de dos años que acuden al Centro de Salud Abdón Calderón.
La protección frente a las enfermedades infecciosas se basa en el desarrollo de "inmunidad frente a las mismas" y aunque los términos de vacunación e inmunización son utilizados de forma similar, tienen sin embargo significados diferentes. Ya que la vacunación describe la administración de una vacuna o toxoide a diferencia de la inmunización que es el proceso de inducir o proporcionar inmunidad.
El objetivo fue determinar el nivel de conocimientos que tienen las madres de los niños menores de dos arias sobre enfermedades inmuno-prevenibles por vacunación y mediante el análisis de datos identificar coma este influye en la salud del nitro y proponer estrategias de modificación para ayudar a las madres a mejorar dichos conocimientos satisfaciendo sus necesidades.
La técnica de investigación empleada file la encuesta, basada en un cuestionario de 15 preguntas cerradas. El procesamiento de datos permitió la medición de conocimiento de las madres que acuden al Centro de salud Abdón Calderón.El resultado que se obtuvo en la investigación es la siguiente: El 50% de madres de los niños menores de dos altos no poseen un conocimiento teórico práctico sobre en el esquema de vacunación y enfermedades inmuno-prevenibles es por ello que se realizó la implementación de una guía didáctica sobre enfermedades inmuno-prevenibles par vacunación en niños menores de dos at-los la misma que sera entregada a la coordinadora del centro de Salud Abdón Calderón.
Semiotic Analysis of Joyce Kilmer’s Poems
Authors: Talibong Emelyn Magsipoc 
Published: October 2021

This study which is a semiotic analysis of the poems of Joyce Kilmer had discovered through the use of Barth’s Denotation-Connotation Theory the use of both literal and non-literal meanings of some important recurring words in Kilmer’s poems. The recurring words serving as leitmotifs were therefore subjected to semiotic analysis and interpretation. The study did explore, therefore, the signs (visual images in the poems) by giving the signifier and the signified of some word/s as signs. With the Denotation-Connotation of the word, it even led the researcher to a new level of signified – something higher in meaning than the two, connotative still. Moreover, the use of semiotic analysis of the poems even became a tool to= experience side benefits of the study – that is, giving a researcher a cue that Joyce Kilmer's poems revolved around nature, God as thematic content with emotion overflowing in the literary opuses. Thus, with the side benefits, the researcher was even led further to realize that the poet (Joyce Kilmer) belonged to the Romantic Era of the literary movement.
Rancang bangun sistem deteksi suhu tubuh dan hand sanitizer nirsentuh pada prototype pintu geser otomatis
Authors: Mas`udia Putri Elfa , Kusumawardhani Mila , Marya Dianthy , Varadiba Khayyinah , Bagaskara Marviyanto Etnika 
Published: October 2021

Dalam situasi pandemi Covid-19, roda perekonomian harus tetap berjalan dengan mengedepankan protokol kesehatan. Melansir dari keputusan menteri kesehatan bahwa setiap kantor di Indonesia yang tetap melaksakan Work From Office selama PSBB berlangsung maka harus melakukan pengukuran suhu tubuh, menyediakan hand sanitizer dengan konsentrasi alkohol minimal 70% atau menyediakan sarana cuci tangan di depan pintu masuk. Masalah yang sering terjadi adalah pengukuran suhu tubuh masih dilakukan secara manual oleh satpam kantor, dan tidak terbiasanya para karyawan untuk menggunakan hand sanitizer. Sebagai upaya pendisiplinan karyawan, maka dirancang prototype pintu otomatis yang hanya bisa terbuka jika suhu tubuh normal dan karyawan sudah menggunakan hand sanitizer. Deteksi suhu tubuh dilakukan menggunakan sensor suhu MLX90614 dan deteksi objek tangan menggunakan sensor infrared. Pintu geser digerakkan oleh Stepper Motor NEMA 17, pintu secara otomatis akan terbuka ketika suhu terdeteksi normal, jika tidak maka buzzer akan berbunyi dan pintu tetap tertutup. Hasil dari penelitian ini memperoleh hasil pengujian keakuratan sensor suhu MLX90614 sebesar 96.8%, posisi tangan optimal yaitu posisi tangan menengadah dengan jarak 1cm terhadap sensor, dan volume hand sanitizer yang cukup untuk mengcover seluruh telapak tangan dewasa adalah pada delay 500 ms yaitu sebesar 2.2991 gram.

During the Covid-19 pandemic, the economics activities must go on with strict health protocols. From the recommendation of health ministry, that every office in Indonesia that still performs Work From Office during the pandemic, temperature measurements must be carried out at the entrance to the office and hand sanitizer that contains minimum of 70% alcohol or hand washing facilities must be provided as well. The problem is that body temperature measurements are still done manually by security officer, and some employees are still not familiar to use hand sanitizer periodically. As an option to make employees discipline, a prototype of automatic door is designed in this research. It can only open if the body temperature of employee is normal and the employee has used hand sanitizer. Body temperature detection is carried out by using the MLX90614 temperature sensor and hand object detection will utilize infrared sensor. The sliding door is driven by the NEMA 17 Stepper Motor, the door will automatically open when the temperature is detected normally, otherwise the buzzer will sound and the door will be still closed. From the testing results in this research, the accuracy of the MLX90614 temperature sensor is 96.8%, the optimal position of the hand is 1 cm from the sensor with looking up position. And the volume of the hand sanitizer that is sufficient to cover all adult palms with 500 ms delay is 2.2991 grams.
Improvement of Nicotine Removal and Ethanol Fermentability From Tobacco Stalk by Integration of Dilute Sulfuric Acid Presoak and Instant Catapult Steam Explosion Pretreatment
Authors: Zhang Hongsen , Fu Chenqing , Ren Tianbao , Xie Hui , Mao Guotao , Wang Zhimin , Wang Fengqin , Song Andong 
Published: October 2021

The nicotine from tobacco stalk showed obvious inhibitory effect on the activity of cellulase and fermentability of microorganisms, which seriously hinders the utilization of tobacco stalk. Dilute sulfuric acid presoak of tobacco stalk was used to enhance the performance of instant catapult steam explosion (ICSE) for tobacco stalk pretreatment. The presoak was beneficial to break the recalcitrant structure of tobacco stalk, reduce nicotine content to relieve the inhibition on the activity of cellulase and metabolism of microorganisms, and promote the performance of enzymatic hydrolysis and ethanol fermentation. The optimized 0.8% sulfuric acid (w/w) presoak–integrated ICSE pretreatment resulted in 85.54% nicotine removal from tobacco stalk; meanwhile, the total sugar concentration from enzymatic hydrolysis of pretreated tobacco stalk increased from 33.40 to 53.81 g/L (the ratio of dry tobacco stalk to water was 1:8, w/w), ethanol concentration increased 103.36% from 5.95 to 12.10 g/L in flask, compared with separate ICSE pretreatment. Finally, the ethanol concentration achieved the highest 23.53 g/L in a 5-L fermenter with the ethanol yield from the glucose of tobacco stalk hydrolysate achieving 71.40% by increasing the solid loading of the tobacco stalk in the enzymatic hydrolysis process (the ratio of dry tobacco stalk to water was 1:4, w/w). These results achieved the expected purpose of efficient utilization of discarded tobacco stalk.
Semi-Synthesis of Marine-Derived Ilamycin F Derivatives and Their Antitubercular Activities
Authors: Li Jun , Liu Zhiyong , Hong Mingye , Sun Changli , Zhang Tianyu , Zhang Hua , Ju Jianhua , Ma Junying 
Published: October 2021

Tuberculosis (TB) is still a global disease threatening people’s lives. With the emergence of multi-drug-resistant Mycobacterium tuberculosis the prevention and control of tuberculosis faces new challenges, and the burden of tuberculosis treatment is increasing among the world. Ilamycins are novel cyclopeptides with potent anti-TB activities, which have a unique target protein against M. tuberculosis and drug-resistant strains. Herein, ilamycin F, a major secondary metabolite isolated from the marine-derived mutant strain Streptomyces atratus SCSIO ZH16 ΔilaR, is used as a scaffold to semi-synthesize eighteen new ilamycin derivatives (ilamycin NJL1–NJL18, 1–18). Our study reveals that four of ilamycin NJLs (1, 6, 8, and 10) have slightly stronger anti-TB activities against Mtb H37Rv (minimum inhibitory concentration, 1.6–1.7 μM) compared with that of ilamycin F on day 14th, but obviously display more potent activities than ilamycin F on day 3rd, indicating anti-TB activities of these derivatives with fast-onset effect. In addition, cytotoxic assays show most ilamycin NJLs with low cytotoxicity except ilamycin NJL1 (1). These findings will promote the further exploration of structure-activity relationships for ilamycins and the development of anti-TB drugs.
Quantifying the Impacts of Pre- and Post-Conception TSH Levels on Birth Outcomes: An Examination of Different Machine Learning Models
Authors: Sun Yuantong , Zheng Weiwei , Zhang Ling , Zhao Huijuan , Li Xun , Zhang Chao , Ma Wuren , Tian Dajun , Yu Kun-Hsing , Xiao Shuo , Jin Liping , Hua Jing 
Published: October 2021

BackgroundWhile previous studies identified risk factors for diverse pregnancy outcomes, traditional statistical methods had limited ability to quantify their impacts on birth outcomes precisely. We aimed to use a novel approach that applied different machine learning models to not only predict birth outcomes but systematically quantify the impacts of pre- and post-conception serum thyroid-stimulating hormone (TSH) levels and other predictive characteristics on birth outcomes.MethodsWe used data from women who gave birth in Shanghai First Maternal and Infant Hospital from 2014 to 2015. We included 14,110 women with the measurement of preconception TSH in the first analysis and 3,428 out of 14,110 women with both pre- and post-conception TSH measurement in the second analysis. Synthetic Minority Over-sampling Technique (SMOTE) was applied to adjust the imbalance of outcomes. We randomly split (7:3) the data into a training set and a test set in both analyses. We compared Area Under Curve (AUC) for dichotomous outcomes and macro F1 score for categorical outcomes among four machine learning models, including logistic model, random forest model, XGBoost model, and multilayer neural network models to assess model performance. The model with the highest AUC or macro F1 score was used to quantify the importance of predictive features for adverse birth outcomes with the loss function algorithm.ResultsThe XGBoost model provided prominent advantages in terms of improved performance and prediction of polytomous variables. Predictive models with abnormal preconception TSH or not-well-controlled TSH, a novel indicator with pre- and post-conception TSH levels combined, provided the similar robust prediction for birth outcomes. The highest AUC of 98.7% happened in XGBoost model for predicting low Apgar score with not-well-controlled TSH adjusted. By loss function algorithm, we found that not-well-controlled TSH ranked 4th, 6th, and 7th among 14 features, respectively, in predicting birthweight, induction, and preterm birth, and 3rd among 19 features in predicting low Apgar score.ConclusionsOur four machine learning models offered valid predictions of birth outcomes in women during pre- and post-conception. The predictive features panel suggested the combined TSH indicator (not-well-controlled TSH) could be a potentially competitive biomarker to predict adverse birth outcomes.
In-Situ FTIR Study of Heterogeneous Oxidation of SOA Tracers by Ozone
Authors: Wang Runhua , Huang Yajuan , Hu Qian , Cao Gang , Zhu Rongshu 
Published: October 2021

Secondary organic aerosols (SOA) play an important role in global climate change and air quality, and SOA tracers can directly characterize the source and reaction mechanism of SOA. However, it is not well known that whether the tracers can be oxidized or how the instability of the tracers in the atmosphere. In this paper, in-situ FTIR was used to analyze the chemical structure changes of erythritol, analogue of 2-methyl erythritol (AME) that is, a tracer of isoprene SOA, and 2, 3-dihydroxy-4-oxopentanoic acid (DHOPA), a tracer of toluene SOA, when exposed to high concentration of ozone for short periods. Under the condition of 20 ppm ozone exposure for 30 min, the change rate of absorption area of AME at 3,480 and 1700 cm−1 was −0.0134 and 0.00117 int.abs/s, respectively, and the change rate of the absorption area of DHOPA at 1,640 and 3340cm−1 was −0.00191 and 0.00218 int.abs/s, respectively. The pseudo-first-order reaction rate constant kapp were 1.89 × 10−8 and 2.12 × 10−7 s−1, and the uptake coefficients of ozone on the surface of AME and DHOPA were (1.3 ± 0.8) × 10−8 and (4.5 ± 2.7) × 10−8, respectively. These results showed the oxidation processes of AME and DHOPA were slow in the presence of high concentrations of ozone, which implied that AME and DHOPA could be considered to be stable in the atmospheric environment with ozone as the main oxidant.
Regional Differences in Various Risk Factors for Postpartum Depression: Applying Mixed Models to the PRAMS Dataset
Authors: Gifford Janace J. , Pluchino Jenna R. , Della Valle Rebecca , Schwarz Jaclyn M. 
Published: October 2021

Purpose: The purpose of this study was to assess the association between various risk factors with postpartum depression severity using a large dataset that included variables such as previous mental health status, social factors, societal factors, health care access, and other state-wide or region-specific variables.Methods: We obtained the most recently available (2016–2017) dataset from the Pregnancy Risk Assessment Monitoring System (PRAMS), which is a dataset compiled by the Centers for Disease Control (CDC) that collects state-specific, population-based data on maternal attitudes and experiences before, during, and shortly after pregnancy from over 73,000 women in 39 states. We utilized a hierarchical linear model to analyze the data across various levels, with a symptom severity scale (0–8) as the dependent variable.Results: Of the 21 variables included in the final model, nine variables were statistically significant predictors of symptom severity. Statistically significant predictors of increased postpartum depression symptom severity included previous depression diagnosis and depression symptoms during pregnancy, baby not residing with mother, unintentional pregnancy, women with less than a high school degree and more than a college degree, Women Infants Children (WIC) enrollment, and married women. In contrast to these other factors, attendance at a postpartum follow up appointment was associated with significantly increased symptom severity. Age revealed an inverted curve in predicting postpartum symptom severity.Conclusions: There was no significant difference in symptom severity scores across the 39 participating states. Most notably, postpartum depression symptom severity was associated with previous depression diagnosis and previous symptom severity, but our results also reveal novel social and education factors that contribute to the support and well-being of the mother and child.
The Dynamic Immunological Parameter Landscape in Coronavirus Disease 2019 Patients With Different Outcomes
Authors: Tang Guoxing , Huang Min , Luo Ying , Liu Wei , Lin Qun , Mao Liyan , Wu Shiji , Xiong Zhigang , Hou Hongyan , Sun Ziyong , Wang Feng 
Published: October 2021

ObjectivesThe longitudinal and systematic evaluation of immunity in coronavirus disease 2019 (COVID-19) patients is rarely reported.MethodsParameters involved in innate, adaptive, and humoral immunity were continuously monitored in COVID-19 patients from onset of illness until 45 days after symptom onset.ResultsThis study enrolled 27 mild, 47 severe, and 46 deceased COVID-19 patients. Generally, deceased patients demonstrated a gradual increase of neutrophils and IL-6 but a decrease of lymphocytes and platelets after the onset of illness. Specifically, sustained low numbers of CD8+T cells, NK cells, and dendritic cells were noted in deceased patients, while these cells gradually restored in mild and severe patients. Furthermore, deceased patients displayed a rapid increase of HLA-DR expression on CD4+T cells in the early phase, but with a low level of overall CD45RO and HLA-DR expressions on CD4+and CD8+T cells, respectively. Notably, in the early phase, deceased patients showed a lower level of plasma cells and antigen-specific IgG, but higher expansion of CD16+CD14+proinflammatory monocytes and HLA-DR−CD14+monocytic-myeloid-derived suppressor cells (M-MDSCs) than mild or severe patients. Among these immunological parameters, M-MDSCs showed the best performance in predicting COVID-19 mortality, when using a cutoff value of ≥10%. Cluster analysis found a typical immunological pattern in deceased patients on day 9 after onset, which was characterized as the increase of inflammatory markers (M-MDSCs, neutrophils, CD16+CD14+monocytes, and IL-6) but a decrease of host immunity markers.ConclusionsThis study systemically characterizes the kinetics of immunity of COVID-19, highlighting the importance of immunity in patient prognosis.
Feasibility of Using the Hollow Glass Microsphere to Develop Lightweight CAC-GGBFS-Blended Strain-Hardening Cementitious Composites
Authors: Fan Wei , Zhuge Yan , Ma Xing , Chow Christopher W.K. , Gorjian Nima , Liu Yue 
Published: October 2021

Strain hardening cementitious composites (SHCCs) with superior tensile strength and ductility have been utilized as an effective repair material. A corrosion-resistant binder, calcium aluminate cement (CAC)–ground granulated blast-furnace slag (GGBFS) blends, has been introduced into SHCC to expand its application in the concrete sewage network rehabilitation. As a repair material, the lightweight property is particularly favorable as it can broaden its functionality. This article presents a study on developing a novel lightweight CAC-GGBFS-blended SHCC using hollow glass microsphere (HGM), namely, HGMLW-SHCCs. The fine silica sand content was substituted with HGM at 25, 50, 75, and 100 vol% in HGMLW-SHCC. We examined flowability, density, uniaxial compressive behavior, direct tensile behavior, and pseudo strain-hardening indices. Microstructure analysis was also conducted to understand the meso-scale behavior of this new lightweight composite. The newly developed HGMLW-SHCC had a 28-day density of only 1756 kg/m3. Compressive and tensile strengths were determined in the range of 62.80–49.39 MPa and 5.81–4.19 MPa, respectively. All mixtures exhibited significant strain-hardening behavior. Even though the increased HGM content negatively affected the tensile strength of HGMLW-SHCC, it had a positive effect on its ductility. In addition, HGM can reduce crack width and tensile stress fluctuations significantly. The results showed that HGM was a promising material for producing strong and lightweight corrosion-resistant SHCCs to be used as a retrofitting material in the wastewater industry.