bluuebunny/crossref_metadata_2025_split huggingface dataset:
π-Extended Macrocyclic Oligothiophene Heptamer and Tetradecamer: Ringsize Effects on the Physical Properties and Morphological Features
Authors: Shimizu Hideyuki , Huang Pochi , Isomura Eigo , Nishinaga Tohru , Iyoda Masahiko 
Published: July 2021

Abstract
Synthesis, X-ray structural analysis, redox behavior, and morphological features of π-extended macrocyclic oligothiophene heptamer and tetradecamer are reported. Due to nanophase separation between inner and outer domains, butyl-substituted π-extended macrocyclic oligothiophenes exhibit marked ringsize effects in the solid state. Among macrocycles with the same composition formula, heptamer has a round shape-persistent structure to produce crystals, whereas the corresponding tetradecamer shows morphological diversity to form single crystals, rods, ovals, and balls. The surface structures of small rods, ovals, and balls were investigated by absorption spectra and PXRD analysis. By cyclic voltametric analysis, heptamer and tetradecamer exhibit reversible two-step redox behavior reflecting moderate donor ability, and the first oxidation potentials of heptamer and tetradecamer are roughly consistent with their HOMO levels.
Das Ende einer alten Brunnstube
Authors: Matt Christoph Ph. 
Published: July 2021

Am Südende des Gerberbergleins wurden die Fundamente eines ehemaligen Hauses, Mauerwerk eines Abwasserkanals sowie eine noch intakte Brunnstube freigelegt.
Der Richt- oder Gerberbrunnen - der erstmals 1290 erwähnt wurde - ist nur einer unter vielen Brunnen, die als sog. Lauf- bzw. Lochbrunnen die Wasserversorgung der Bevölkerung Basels sicherzustellen hatten. Hingegen war nur mit diesem Brunnen bzw. mit seinem Standort eine Sage untrennbar verknüpft: nämlich dass hier einst ein Basilisk gehaust habe, auf den - nach Meinung verschiedener alter Schriftsteller - auch der Name der Stadt Basel zurückgehen soll.
Basel - Etappen der Befestigung einer Stadt
Authors: Helmig Guido 
Published: July 2021

Die Stadt Basel kann auf eine über 2000 Jahre alte Geschichte zurückblicken. Die verkehrsgeographisch günstige Lage am Rheinknie hat sicher wesentlich zu ihrem Aufschwung beigetragen.
Im Artikel wird der Forschungsstand zu den verschiedenen Basler Befestigungen (Oppidum, Militärstützpunkt, Kastell, Burkhardsche Stadtmauer, Innere Stadtmauer, Befestigung der Vorstädte, Äussere Stadtmauer, barockzeitliche Festungsbauten, letzte Stadterweiterung im 19. Jahrhundert) zusammengetragen.
WIND (Workflow for pIRNAs aNd beyonD): a strategy for in-depth analysis of small RNA-seq data
Authors: Geles Konstantinos , Palumbo Domenico , Sellitto Assunta , Giurato Giorgio , Cianflone Eleonora , Marino Fabiola , Torella Daniele , Mirici Cappa Valeria , Nassa Giovanni , Tarallo Roberta , Weisz Alessandro , Rizzo Francesca 
Published: July 2021

Current bioinformatics workflows for PIWI-interacting RNA (piRNA) analysis focus primarily on germline-derived piRNAs and piRNA-clusters. Frequently, they suffer from outdated piRNA databases, questionable quantification methods, and lack of reproducibility. Often, pipelines specific to miRNA analysis are used for the piRNA research in silico. Furthermore, the absence of a well-established database for piRNA annotation, as for miRNA, leads to uniformity issues between studies and generates confusion for data analysts and biologists. For these reasons, we have developed WIND (Workflow for pIRNAs aNd beyonD), a bioinformatics workflow that addresses the crucial issue of piRNA annotation, thereby allowing a reliable analysis of small RNA sequencing data for the identification of piRNAs and other small non-coding RNAs (sncRNAs) that in the past have been incorrectly classified as piRNAs. WIND allows the creation of a comprehensive annotation track of sncRNAs combining information available in RNAcentral, with piRNA sequences from piRNABank, the first database dedicated to piRNA annotation. WIND was built with Docker containers for reproducibility and integrates widely used bioinformatics tools for sequence alignment and quantification. In addition, it includes Bioconductor packages for exploratory data and differential expression analysis. Moreover, WIND implements a "dual" approach for the evaluation of sncRNAs expression level quantifying the aligned reads to the annotated genome and carrying out an alignment-free transcript quantification using reads mapped to the transcriptome. Therefore, a broader range of piRNAs can be annotated, improving their quantification and easing the subsequent downstream analysis. WIND performance has been tested with several small RNA-seq datasets, demonstrating how our approach can be a useful and comprehensive resource to analyse piRNAs and other classes of sncRNAs.
Abdominal tuberculosis misdiagnosed as acute surgical abdomen and carcinomatosis
Authors: Meregildo-Rodriguez Edinson Dante , Tafur-Ramirez Rosita Claudia , Espino-Saavedra Walter Giovanny , Angulo-Prentice Sonia Fiorella 
Published: July 2021

Tuberculosis is a major public health problem worldwide. Tuberculosis can be confused with other diseases and its diagnosis is frequently delayed, especially in areas of low prevalence. Abdominal tuberculosis includes involvement of the gastrointestinal tract, peritoneum, lymph nodes, and/or solid organs; and accounts for 5% of all cases of tuberculosis. We report two cases of young patients who presented preoperatively as acute abdomen due to acute appendicitis. During surgery, these cases were misdiagnosed as “carcinomatosis”, and in the postoperative period these cases were complicated with septic shock. In both cases, histopathology showed caseating granulomas which suggested tuberculous peritonitis and enteritis. Subsequently, RT-PCR in peritoneal fluid confirmed Mycobacterium tuberculosis. In one case the clinical response to treatment was excellent, and the other case was fatal. The aim of this report is to bring attention to the spectrum of tuberculosis, and to serve as a reminder of tuberculosis as the great imitator that can masquerade as cancer. Most tuberculous patients erroneously diagnosed as cancer have extensive “neoplastic” lesions that would suggest an advanced-stage malignancy. Assuming a case as an advanced cancer would reduce the chance of performing more exhaustive studies to get a definitive diagnosis and clinicians would be tempted to offer only palliative treatments.
Musculoskeletal disorders in basketball players and associated factors: a systematic review protocol with meta-analysis
Authors: Cristina de Carvalho Borges Silvia , da Silva Valadão Fernandes Michele , Noll Priscilla Rayanne e Silva , Diniz Azevedo Vinicius , Márcia Ferreira Silva Regina , Rodrigues Mendonça Carolina , Noll Matias 
Published: July 2021

Introduction: Musculoskeletal disorders play an important role in athletes’ health and success in sports; they are the main contributors to disability, and back pain is a common problem in athletes. Back pain and spinal injuries occur in players because of the repetitive and unilateral body overload during sports practice. Reviews focused on musculoskeletal disorders in basketball players are scarce in the literature. We describe a systematic review protocol for assessing the prevalence of musculoskeletal disorders and the associated factors in basketball players. Methods and analysis: The protocol will be based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) items and articles will be searches in the databases EMBASE, PubMed, and Scopus. Studies will be included if they are written in English and without restriction regarding the search period. All research stages will be performed by two independent reviewers and will be conducted using Rayyan. Potential disagreements will be analyzed by a third reviewer. The inter-rater reliability will be determined through the Cohen's kappa coefficient. Evidence quality will be ascertained by using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) system, while the Downs and Black checklist will be used for assessing the risk of bias. A descriptive summary and presentation of the characteristics and findings of all included studies will be provided in a table. Regarding these data, if there are sufficient high-quality studies, we plan to perform a meta-analysis. Discussion: The obtained results might possibly relate back pain to postural changes in this population. In addition, the data will be compared based on gender and different age groups. It is expected that the results can support the implementation of programs and actions for prevention, ultimately aiming at improving health, quality of life, and sports performance. Registration: PROSPERO CRD42020201653 on August, 31, 2020.
Italian public’s views on sharing genetic information and medical information: findings from the ‘Your DNA, Your Say’ study
Authors: Romano Virginia , Milne Richard , Mascalzoni Deborah 
Published: July 2021

Background: The collection and sharing of genomic and health data underpins global efforts to develop genomic medicine services. ‘Your DNA, Your Say’ is a cross-sectional survey with the goal of gathering lay public attitudes toward the access and sharing of deoxyribonucleic acid (DNA) information and medical information. It suggests significant international variation in the willingness to share information, and in trust in the actors associated with the collection and use of this information. This paper explores these questions in the Italian context. Methods: The Italian Your DNA, Your Say campaign led to the collection of 1229 valid questionnaires. The sample was analysed using standard descriptive statistics. We described the sample in terms of gender, age ranges and self-reported religiosity, and split the sample amongst the five typically studied Italian macro-areas to explore regional variation. We analysed the relationship between these factors and trust and willingness to share medical and DNA information. Results: The majority of the sample, across all socio-demographics, were willing to share DNA and health information with all entities considered except for-profit researchers. Respondents tended not to trust institutions beyond their own doctor. There was no difference between Italian regions. Conclusions: Despite the generally positive attitude towards sharing, we suggest that the lack of trust in non-profit researchers and the government needs to be better understood to inform public communication projects around genomics in the future and to enhance awareness of DNA and medical information in Italy.
Desconcentração regional e diversificação da indústria no Estado do Rio de Janeiro – 2003/2014
Authors: Lacerda Henrique Schmidt dos Reis , Saboia João 
Published: July 2021

As mudanças sofridas pela indústria brasileira na última década e meia modificaram o parqueindustrial geograficamente e setorialmente. O estudo aqui desenvolvido cobre o período 2003/2014 e procura identificar a dinâmica industrial, analisando seus efeitos em termos da distribuição regional e setorial da indústria no estado do Rio de Janeiro. Utilizando dados da RAIS para as variáveis emprego, número de estabelecimentos, massa salarial e salário médio, o trabalho destaca as principais mudanças ocorridas no Rio de Janeiro. Uma de suas características é o papel do setor petroleiro, que se desenvolve rapidamente no período e transforma Macaé em um importante polo industrial do estado. O processo de desconcentração regional e diversificação setorial da indústria fluminense ocorre de forma heterogênea e o estudo busca identificá-lo destacando as principais microrregiões fluminenses.
Desinstitucionalização: análise dos direitos fundamentais e saúde mental pública
Authors: Silva Victoria Muniz Cabral da , Lima Paolla Vieira 
Published: July 2021

O artigo a seguir aborda a política pública de desinstitucionalização da saúde mental. Para tanto, utilizaremos os indicadores do município do Rio de Janeiro, produzidos pela Secretaria Municipal de Saúde. Com isso, poderemos verificar a congruência da implementação da supradita política pública, estabelecendo uma análise com seus objetivos. Além disso, o estudo dessa correlação trará subsídios para averiguar se a desinstitucionalização como política pública está apropriada com a concretização dos direitos fundamentais. A metodologia será norteada pela observação de indicadores produzidos pelo monitoramento interno, baseado na abordagem teórica multidisciplinar entre direitos e psiquiatria.
Projection optical engine design based on tri-color LEDs and digital light processing technology
Authors: Jiang Haonan , Lin Zibin , Li Yao , Yan Yinguo , Zhou Ziping , Chen Enguo , Yan Qun , Guo Tailiang 
Published: July 2021

Digital light processing (DLP) is currently a cutting-edge technology for desktop projection optical engines. Due to the passive luminescence characteristics, the DLP projection engine needs a few specific illumination optical components for light collimation, homogenization, and color combination, together with a projection lens matching the DLP chip and magnifying the image. In this paper, we propose a design approach that first splits the DLP projection optical engine into individual components for separate design, and then integrates them into a whole system for further verification. For the first step, the collimating lens group is designed for light collection, and the dichroic mirrors are used to fold the light path based on tri-color LED light sources. For the second step, a fly-eye lens and the corresponding relay lens group are designed to achieve uniform illumination on the DMD chip. The third step is to optimize the projection lens group for high-resolution projection display. Based on the design and simulation, the optical efficiency is 63.4% and the uniformity reaches 94.9% on the projection screen. The modulation transfer function (MTF) of the projection lens is higher than 0.4 at 66 lines for the distance of

500

∼

1500

m
m

, and the distortion is lower than 1%. Simulation results show that the total luminous flux is estimated to reach 224.15 lm when the powers of tri-color LEDs are 21 W, 15.5 W, and 25 W, respectively. A projector prototype is built and tested for further verification, which provides a luminous flux of 220.43 lm and uniformity of 90.22%, respectively. The proposed design, demonstrated by both simulation and experiment, exhibits high feasibility and application potential in state-of-the-art commercial projector design.
Trends of maternal waterpipe, cigarettes, and dual tobacco smoking in Jordan. A decade of lost opportunities
Authors: Kheirallah Khalid A. , Shugaa Addin Nuha , Alolimat Maan M. 
Published: July 2021

Background
Maternal tobacco use is a global public health problem. In the literature, the focus was mainly on cigarette smoking, minimally on waterpipe use, and totally ignored dual use among pregnant women. We estimated the prevalence of current maternal tobacco use by tobacco product (cigarette, waterpipe, and dual use) over a period of ten years (2007 to 2017), and examined the socio-demographic patterning of maternal tobacco use.

Methods
A secondary analysis of Jordan DHS four data waves was conducted for women who reported to be pregnant at the time of the survey. Current cigarette and waterpipe tobacco use were investigated. Prevalence estimates for cigarette-only, waterpipe-only, and dual use, as well as for cigarette, regardless of waterpipe, and waterpipe, regardless of cigarette, were reported. The effect of independent variables on cigarette smoking, waterpipe use, and dual use was assessed. Logistic regression models assessed the adjusted effects of socio-demographic variables on cigarette smoking, waterpipe use, and on dual use. For each outcome variable, a time-adjusted and a time-unadjusted logistic models were conducted.

Results
Over the last decade, the prevalence estimates of current cigarette-only smoking slightly decreased. The prevalence estimates of current waterpipe-only use exceeded those for cigarette-only after 2007 and showed a steady overall increase. Current dual use showed a continuous rise especially after 2009. Gradual increase in cigarette smoking (4.1%, in 2007, and 5.7% in 2017) and in waterpipe use (2.5% to 6.4%) were detected. Education showed an inverse relationship with cigarette and waterpipe smoking. Household wealth demonstrated a positive association with cigarette and waterpipe smoking.

Conclusions
Tobacco use epidemic is expanding its roots among pregnant women in Jordan through not only waterpipe use but also dual cigarette–waterpipe smoking. Maternal and child services should consider tobacco counseling and cessation.
Changes in ischemic heart disease mortality at the global level and their associations with natural disasters: A 28-year ecological trend study in 193 countries
Authors: Huang Kai-Sen , He Ding-Xiu , Huang De-Jia , Tao Qian-Lan , Deng Xiao-Jian , Zhang Biao , Mai Gang , Guha-Sapir Debarati 
Published: July 2021

Background
Natural disasters are believed to be associated with cardiovascular disease. This study aimed to explore the changes in mortality due to ischemic heart disease (IHD) and their associations with natural disasters at the global level.

Methods
Country-specific data on the impact of natural disasters, rates of mortality due to IHD and years of life lost (YLL) and socioeconomic variables were obtained for 193 countries for the period from 1990 to 2017. An ecological trend study was conducted to estimate the changes in the IHD mortality and YLL rates and their associations with natural disasters (occurrence, casualties and total damage). Correlation analyses and multivariate linear regression were used.

Results
Significant changes were found in the IHD mortality and YLL rates and the occurrence of disasters between the two equal periods (1990 to 2003 and 2004 to 2017) (p<0.001). The bivariate Pearson correlation test revealed that the trend in the occurrence of natural disasters was positively correlated with trends in the IHD mortality and YLL rates among females and all individuals (p<0.05) and was marginally correlated among males. Multiple linear regression revealed an independent association between the occurrence of natural disasters and the IHD mortality rate among males, females and all individuals (standardized coefficients = 0.163, 0.357 and 0.241, p<0.05), and similar associations were found for the YLL rate (standardized coefficients = 0.194, 0.233 and 0.189, p<0.05).

Conclusions
Our study demonstrated significant changes in the IHD mortality and YLL rates at the global level and their independent associations with natural disasters. Both males and females were vulnerable to natural disasters. These results provide evidence that can be used to support policy making and resource allocation when responding to disasters and developing strategies to reduce the burden of IHD.
El portafolios digital como herramienta para el desarrollo de competencias transversales en el alumnado
Authors: Rodríguez Illera José Luis , Galván   Fernández Cristina , Martínez Olmo Francesc 
Published: July 2021

Partiendo de un enfoque sobre las relaciones entre las tecnologías digitales como herramientas de mediación, se analiza el papel de un caso concreto, los portafolios electrónicos, para la mejora de competencias transversales en el ámbito universitario. Los resultados indican que se obtienen mejoras, como mínimo desde la percepción de los propios estudiantes, en algunas dimensiones ligadas a la capacidad para seleccionar y organizar información, así como a la planificación del aprendizaje.
Tensiones y dilemas en la educación de personas adultas
Authors: Rumbo Arcas Begoña 
Published: July 2021

De una sociedad asentada en la racionalidad “moderna” en que la educación de las personas adultas buscaba alcanzar la emancipación social, hemos evolucionado hacia una sociedad legitimada por una nueva racionalidad en la que la educación de las personas adultas se convierte en una mercancía al servicio del nuevo mercado global y de los nuevos valores culturales postmodernos. Obviamente, estos cambios conllevan la aparición de “nuevos discursos” que tratan el concepto de la educación de personas adultas como sinónimo de otros conceptos más pragmáticos y con una finalidad resolutiva de los problemas del mundo actual. Aprender significa responder de manera eficiente a las rápidas y cambiantes necesidades del mercado. La educación se transforma en educación a lo largo de la vida y el lugar de trabajo actúa como una organización de aprendizaje.
AICLE a través de las lenguas: resultados de la investigación en dos comunidades bilingües
Authors: Ruiz De Zarobe Yolanda , Celaya M. Luz 
Published: July 2021

El Aprendizaje Integrado de Contenidos en Lengua Extranjera (AICLE) se ha aceptado en los últimos años como uno de los enfoques educativos preferidos para desarrollar el multilingüismo en Europa. España ha seguido asimismo esta tendencia, aunque su implantación difiere según las comunidades, bien sean monolingües bien bilingües, ya que en este último caso el aprendizaje de la lengua extranjera, normalmente el inglés, debe acomodarse a las dos lenguas ya existentes en la comunidad. El objeto de este artículo es llevar a cabo una comparación de la competencia lingüística obtenida en dos comunidades bilingües, el País Vasco y Cataluña, en dos entornos educativos distintos: por un lado, un acercamiento tradicional al aprendizaje del inglés como asignatura (no-AICLE) y, por otro, un entorno integrado AICLE. En concreto, analizaremos la competencia escrita que estudiantes de educación secundaria obtienen en estas dos comunidades cuando se analizan variables distintas. En primer lugar, compararemos el enfoque educativo desarrollado en las dos comunidades (AICLE y no-AICLE) y, en segundo lugar, estudiaremos la influencia del número de horas de instrucción en dos grupos de edad distintos. Los resultados vienen a corroborar cómo la cantidad de instrucción en lengua extranjera influye de forma significativa en los resultados en competencia escrita, sea cual sea el enfoque educativo seguido en el aula.