bluuebunny/crossref_metadata_2025_split huggingface dataset:
Insecticidal efficacy of afoxolaner against bedbugs, Cimex lectularius, when administered orally to dogs
Authors: Beugnet Frederic , Rautenbach Carin , van der Mescht Luther , Lebon Wilfried , Aouiche Nesrine , Liebenberg Julian 
Published: February 2021

The objective of this experimental study was to assess the insecticidal efficacy of afoxolaner (NexGard®) against bedbugs (Cimex lectularius) on dogs. For each challenge, 20 bedbugs were placed in two chambers positioned in contact to the dog’s skin for 15 min, after which live fed parasites were counted and incubated for survival evaluations. On Day 0, 7 dogs assigned to the treated group were administered afoxolaner orally at the registered dose. All 14 dogs were challenged on Days 1, 7, 14, 21 and 28, and the collected live fed C. lectularius incubated for 72 h (Day 1), and 72 h and 96 h (Days 7, 14, 21 and 28) for survival evaluation. The percent feeding in the control group ranged from 95% to 98.6% and the percent of live fed bedbugs at 96 h ranged from 99.3% to 100% in the control group, demonstrating the viability of the strain and their capacity to feed on dogs. Significantly fewer live fed bedbugs were counted in the treated group, compared to the control group, at all time-points. The reduction of live fed C. lectularius in the afoxolaner group was 41.4% at 72 h after the Day 1 challenge, and 77.2%, 82.7%, 85.0% and 63.5% at 96 h after the Days 7, 14, 21 and 28 challenges, respectively. It is hypothesized that monthly treatment of dogs with afoxolaner could help in preventing a bed bug population from installing in a household if bedbugs bite dogs in the presence of humans.
Temporal bone primary inverted papilloma – Case Report and review of the literature
Authors: Avallone Emilio , Raab Peter , Lenarz Thomas , Willenborg Kerstin Marion 
Published: February 2021

AbstractInverted papilloma of middle ear is an extremely rare lesion of the respiratory epithelium that normally occurs in the nasal cavity and paranasal sinuses. So far less than 17 cases were described in literature. A 45-year-old patient was admitted in our Department with hearing loss, otorrhea and pulsing tinnitus on the right ear. The clinical examination showed a granulation tissue on the right eardrum. No tumor formation was seen in the nasal cavity. The MRI showed a tissue formation in the tympanic cavity with an extension in the middle cranial fossa. A mastoidectomy with antrotomy and duraplasty was performed. The histological diagnosis was inverted papilloma of the middle ear. In a second step occurred an eradication of the tumor with a subtotal petrosectomy. The etiology of the inverted papilloma of the middle ear is unknown. Our case is so far the 18nd case described.Our experience has shown that the eradication of the tumor with a subtotal petrosectomy resulted as reasonable procedure. A long-term follow-up is suggested in order to detect possible recurrence or malignant transformation.
Affektive Erkrankungen bei Geflüchteten kultursensibel behandeln
Authors: Strupf Michael , Wiechers Maren , Übleis Aline , Padberg Frank 
Published: February 2021

SummaryKultursensible Psychotherapie ist ein wichtiger Bestandteilin der Versorgung von PatientInnen mit Fluchterfahrungenund psychischen Erkrankungen. DolmetschergestützteGruppentherapie stellt im Speziellen ein effektivesund gut durchführbares Behandlungsangebot fürgeflüchtete PatientInnen dar. Der Artikel erläutert anhandvon zwei Fallbeispielen Inhalte, praktische Anwendungund Herausforderungen einer psychotherapeutischenIntervention (Empowerment) für Geflüchtete mitaffektiven Erkrankungen.
Dritte im Bunde – Psychotherapie unter Einsatz von SprachmittlerInnen
Authors: Wiechers Maren , Strupf Michael , Sarwary Brishna , Übleis Aline , Padberg Frank 
Published: February 2021

SummaryDer Einsatz von DolmetscherInnen in der Psychotherapieermöglicht effektive und kultursensible Interventionenbei PatientInnen mit Migrations- und Fluchterfahrung.Die Möglichkeit, das eigene Erleben in der Muttersprachezu artikulieren, befähigt die PatientInnen, sich imSinne eines Empowerment-Prinzips aktiv am therapeutischenProzess zu beteiligen. Die Gesprächssituation zudritt bringt jedoch auch Herausforderungen mit sich,weshalb eine klare Rollenverteilung notwendig ist.
Clinical Characteristics of Mother–Infant Dyad and Placental Pathology in COVID-19 Cases in Predominantly African American Population
Authors: Jani Sanket , Jacques Suzanne M , Qureshi Faisal , Natarajan Girija , Bajaj Sujit , Velumula Pradeep , Agu Cindy , Bajaj Monika 
Published: February 2021

Objective In this currently evolving coronavirus disease 2019 (COVID-19) pandemic, the evidence is scarce about the impact of COVID-19 infection on women in labor and neonates in an inner city African-Americans (AA) population. The objective of this study was to evaluate the clinical outcomes and placental pathology in mother–infant dyads in COVID-19 cases.
Study Design Retrospective chart review was conducted on 34 COVID-19 positive mother–infant dyads to study their baseline characteristics and outcomes. Placental pathology was reviewed by two perinatal pathologists.
Results COVID-19 was noted in 3% of pregnant women who delivered in our institution. The majority (82%) of them were asymptomatic. Out of the four mothers who were symptomatic, only three (9%) required supplemental oxygen. None of them required invasive ventilation. All the neonates tested negative for COVID-19 at 24 hours of age. There were no gross or microscopic pathological abnormalities detected that could be definitely associated with any COVID-19 related complications during pregnancy in any of the 34 placentas.
Conclusion COVID-19 does not appear to increase morbidity and mortality among pregnant women and their neonates in a predominantly AA population. Our study did not find any evidence of vertical transmission of COVID-19 infection nor any specific findings on placental pathology.
Key Points
Tubular Ileal Duplication Causing Perforative Peritonitis in an Adult: A Rare Presentation
Authors: Gandhi Jignesh A. , Shinde Pravin H. , Churiwala Jayati J. , Husain Sakina 
Published: February 2021

Abstract
Background Enteric duplication cysts are a rare congenital abnormality that present more commonly in children than adults. Clinical presentation varies from vague abdominal pain, abdominal lump, iron deficiency anemia to intestinal obstruction due to intussusception or mass effect. We report a tubular ileal duplication in an adult male presenting with an acute abdomen due to perforative peritonitis.
Case A 20-year-old male presented to the emergency department with complains of right lower abdominal pain. On clinical examination and ultrasound scan patient was suspected to have a complicated acute appendicitis (rupture). However, a computed tomography scan was suggestive of perforation in the distal ileum. Emergency exploratory laparotomy revealed a perforated isolated ileal tubular duplication.
Anticoagulant Treatment for Splanchnic Vein Thrombosis in Liver Cirrhosis: A Systematic Review and Meta-Analysis
Authors: Valeriani Emanuele , Di Nisio Marcello , Riva Nicoletta , Cohen Omri , Porreca Ettore , Senzolo Marco , De Gottardi Andrea , Magaz Marta , Garcia-Pagan Juan-Carlos , Ageno Walter 
Published: February 2021

Abstract
Background Splanchnic vein thrombosis (SVT) is a common complication in patients with liver cirrhosis. The aim of this study was to evaluate the efficacy and safety of anticoagulant therapy for SVT in cirrhotic patients.
Methods In this systematic review and meta-analysis, studies reporting on SVT recanalization and progression, recurrent venous thromboembolism (VTE), major bleeding, and overall mortality were searched in MEDLINE, EMBASE, and ClinicalTrial.gov up to December 2019. Pooled proportions and risk ratios (RRs) with corresponding 95% confidence intervals (CIs) were calculated.
Results A total of 1,475 patients were included in 26 studies (23 observational and 3 randomized controlled trials). In patients receiving anticoagulant therapy, SVT recanalization occurred in 68% (95% CI, 62–74; 571/842 patients; 22 studies), SVT progression in 6% (95% CI, 4–9; 25/748 patients; 22 studies), recurrent VTE in 10% (95% CI, 4–22; 48/399 patients; 7 studies), major bleeding in 6% (95% CI, 4–10; 58/785 patients; 18 studies), and overall mortality in 9% (95% CI, 6–14; 68/787 patients; 17 studies). Anticoagulant treatment was associated with higher SVT recanalization (RR 3.19; 95% CI, 1.42–7.17), lower thrombosis progression (RR 0.28; 95% CI, 0.15–0.52), major bleeding (RR 0.52; 95% CI, 0.28–0.97), and overall mortality (RR 0.42; 95% CI, 0.24–0.73) compared with no treatment.
Conclusion Anticoagulant therapy seems to improve vein recanalization and to reduce SVT progression, major bleeding, and overall mortality in cirrhotic patients with SVT. The incidence of recurrent VTE during anticoagulation remains substantial.
Impact of the COVID-19 Pandemic on Physicians Working in the Head and Neck Field
Authors: Imamura Rui , Bento Ricardo F. , Matos Leandro L. , William William N. , Marta Gustavo N. , Chaves Aline L. F. , Castro Gilberto de , Kowalski Luiz P. 
Published: February 2021

Abstract
Background With the COVID-19 pandemic, the clinical practice of physicians who work in the head and neck field in Brazil dropped dramatically. The sustained impact of the pandemic is not known.
Methods An anonymous online survey was distributed to Brazilian otolaryngologists, head and neck surgeons, medical and radiation oncologists, asking about their clinical practice in the third to fourth months of the pandemic.
Results The survey was completed by 446 specialists. About 40% reported reduction of more than 75% in outpatient care. A reduction of 90% to 100% in airway endoscopies was reported by 50% of the responders, and the same rate of reduction regarding surgeries (pediatric or nasosinusal) was reported by 80% of them. Family income decreased by 50%, and the psychological burden on physicians was considerable. The availability of personal protective equipment and safety precautions were limited, especially in the public sector.
Conclusion COVID-19 is still impacting the head and neck field, and safety concerns may hinder the prompt resumption of elective care.
Genetics of Dentofacial and Orthodontic Abnormalities
Authors: Neela Praveen Kumar , Atteeri Anjana , Mamillapalli Pavan Kumar , Sesham Vasu Murthy , Keesara Sreekanth , Chandra Jaya , Monica Udayini , Mohan Vasavi 
Published: February 2021

AbstractThe development of craniofacial complex and dental structures is a complex and delicate process guided by specific genetic mechanisms. Genetic and environmental factors can influence the execution of these mechanisms and result in abnormalities. An insight into the mechanisms and genes involved in the development of orofacial and dental structures has gradually gained by pedigree analysis of families and twin studies as well as experimental studies on vertebrate models. The development of novel treatment techniques depends on in-depth knowledge of the various molecular or cellular processes and genes involved in the development of the orofacial complex. This review article focuses on the role of genes in the development of nonsyndromic orofacial, dentofacial variations, malocclusions, excluding cleft lip palate, and the advancements in the field of molecular genetics and its application to obtain better treatment outcomes.
Publication Parameters for Medical Faculty Promotions: A Survey on the Medical Council of India Amendment 2019 with Review of Literature
Authors: Patra Anurima , Gibikote Sridhar , Khera Pushpinder S. , Kalra Naveen , Keshava Shyamkumar N. 
Published: February 2021

Objective
The aim of this study was to gather the opinion of medical practitioners in India regarding the modifications in the recently released MCI (Medical Council of India) circular for faculty promotion criteria across medical colleges in the country and their suggestions for further changes.

Materials and Methods
An 11-set validated online questionnaire was circulated among medical practitioners across various medical colleges in the country, open for a period of 8 days between 5 to 12 June, 2020. The participants in this online survey were asked to rank the order of authors and types of manuscripts on a scale of 0 to 1 with increments of 0.1 and were also asked for an opinion regarding indexing, inclusion of impact factor of the journal, and citation indices.

Results
There were 182 respondents included in the survey, belonging to 12 different states. Majority of the doctors participating in the survey were professors (37.3%, 68/182). About 81.3% (148/182) doctors were aware of the latest MCI guidelines. Opinion for adding citations to the promotion criteria was expressed by 59.3% (108/182). There was a general suggestion to include number of citations, and Google Scholar as citation service. A scoring table was proposed based on the responses, to rank various publications.

Conclusion
As per the survey, more than 80% of the medical practitioners were aware of the recent update by MCI for faculty promotion. The participants expressed that the exiting guidelines may be further modified by the inclusion of all authors and all types of manuscripts into the criteria, based on a graded score system.
Further Evidence of a Recessive Variant in COL1A1 as an Underlying Cause of Ehlers–Danlos Syndrome: A Report of a Saudi Founder Mutation
Authors: Almatrafi Ahmad , Hashmi Jamil A. , Fadhli Fatima , Alharbi Asma , Afzal Sibtain , Ramzan Khushnooda , Basit Sulman 
Published: February 2021

AbstractEhlers–Danlos syndrome (EDS) is a group of clinically and genetically heterogeneous disorder of soft connective tissues. The hallmark clinical features of the EDS are hyperextensible skin, hypermobile joints, and fragile vessels. It exhibits associated symptoms including contractures of muscles, kyphoscoliosis, spondylodysplasia, dermatosparaxis, periodontitis, and arthrochalasia. The aim of this study is to determine the exact subtype of EDS by molecular genetic testing in a family segregating EDS in an autosomal recessive manner. Herein, we describe a family with two individuals afflicted with EDS. Whole exome sequencing identified a homozygous missense mutation (c.2050G > A; p.Glu684Lys) in the COL1A1 gene in both affected individuals, although heterozygous variants in the COL1A1 are known to cause EDS. Recently, only one report showed homozygous variant as an underlying cause of the EDS in two Saudi families. This is the second report of a homozygous variant in the COL1A1 gene in a family of Saudi origin. Heterozygous carriers of COL1A1 variant are asymptomatic. Interestingly, the homozygous variant identified previously and the one identified in this study are same (c.2050G > A). The identification of a unique homozygous mutation (c.2050G > A) in three Saudi families argues in favor of a founder effect.
The Keloid Intervention Benefit Inventory 21: A New Assessment Tool for the Quality of Life of Patients with Auricular Keloids
Authors: Häussler Daniel , Hüttemann Stefanie , Weiß Christel , Rotter Nicole Karoline , Sadick Haneen 
Published: February 2021

AbstractThe assessment of the quality of life (QoL) of patients with chronic diseases before and after medical interventions has gained increasing importance in recent decades. Particularly for patients with visible keloid scars in the head and neck region, standardized measurement tools are either absent or have been shown to be insufficient. The aim of the present study was to create a new standardized questionnaire that is specific to auricular keloid patients and reflects their clinical symptoms and QoL. The Keloid Intervention Benefit Inventory 21 (KIBI-21) questionnaire was developed in two stages. First, a group of experts identified a pool of 26 questions and modified and supplemented the items through a comparison with existing QoL assessments so that they related to keloid-specific clinical symptoms and the QoL of patients with auricular keloids before and after a medical intervention. This questionnaire was distributed to 27 outpatients who had undergone medical interventions for visible auricular keloids. Second, a sequential statistical analysis was conducted. This included a single-item assessment and reduction, analysis for internal consistency, construct validity, and divergence validity as well as a factor analysis. The analyses were performed for the entire questionnaire and for the items in the subcategories General Health, Physical Symptoms, Self-Esteem, and Social Impact. The final version of this newly validated and standardized KIBI questionnaire consisted of 21 items, of which each item was assigned to only one subscale. The questionnaire showed a Cronbach's α of 0.84 with a good internal consistency. In the item correlation validity, strong associations were found in all subscales, except for the Social Impact Subscale. The keloid-specific QoL questionnaire KIBI-21 proved to be a reliable and reproducible instrument to assess the QoL and clinical symptoms in patients suffering from auricular keloids before and after a medical treatment.
Identity formation of the profession in a latecomer political science community
Authors: Molnár Gábor Tamás , Ilonszki Gabriella 
Published: February 2021

AbstractLatecomer political science communities have faced multiple challenges in the past decades, including the very establishment of their professional identities. Based on the case study of Hungary, this article argues that publication performance is a substantial component of the identity of the political science profession. Hungary is a notable example among Central and East European (CEE) political science academia in the sense that both the initial take-off of the profession and then its increasing challenges are typical to the CEE region. In an inclusive approach, which encompasses all authors published in the field between 1990 and 2018, as well as their publication record, the analysis demonstrates that political science has undergone major expansion, quality growth and internationalisation but these performance qualities are unevenly spread. These reflect important aspects of the profession’s identity. This agency and performance-based approach to identity formation might well be used to build up identity features elsewhere and also in a comparative manner.
Quintuple AISI 1010 carbon steel core coil for highly focused transcranial magnetic stimulation in small animals
Authors: Carmona Ivan C. , Kumbhare Deepak , Baron Mark S. , Hadimani Ravi L. 
Published: February 2021

Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation technique used to regulate the synaptic activity of neurons in the brain, improving the functionality of connecting regions and bringing effective treatment to different neurological and psychiatric disorders. The TMS induced E-field needs to be focal enough to avoid unwanted side effects caused by stimulation of the regions adjacent to the target. Attempts at TMS in small animals like rodents are highly constrained, since most of these studies use commercial equipment intended for humans, with power and coil geometries not designed for small animals. Using finite element modeling in ANSYS Maxwell, the present work shows the design and evaluation of customized arrays of two and five dual-winding solenoids, including a ferromagnetic core, to restrict the stimulation to areas as small as 1 mm2. Each solenoid is made with 50 turns of a wire with thickness = 1 mm, height = 25.4 mm and elliptical top-view cross section. Ferromagnetic cores with V-shape tip sharpening were included, using AISI 1010 carbon steel of 2 T of saturation flux density (Bsat) at 4×104 A/m, and an initial relative permeability µr=667.75. Electric fields and magnetic flux densities were calculated around 4.00 mm below the coil (vertical distance from the top of the scalp to the cortical layer 5/6 in adult rats) with peak currents of 10kA, in a single non-repetitive pulse at 2.5kHz. The achieved 100V/m in a small area of 1 mm2 suggests the suitability of the coil for in vivo experimentation in rodents. Future works will seek to improve the duration of the pulses for repetitive TMS with pulse shaping techniques and validate the novel coil with in vivo experiments in rat models.
The endpoint theorem
*
Authors: Scott Susan M , Whale Ben E 
Published: February 2021

Abstract
The endpoint theorem links the existence of a sequence (curve), without accumulation points, in a manifold to the existence of an open embedding of that manifold so that the image of the given sequence (curve) has a unique endpoint. It plays a fundamental role in the theory of the abstract boundary as it implies that there is always an abstract boundary point to represent the endpoint of such sequences and curves. The endpoint theorem will be of interest to researchers analysing specific spacetimes as it shows how to construct a chart in the original manifold which contains the sequence (curve). In particular, it has application to the study of singularities predicted by the singularity theorems.
High-accuracy differential resonant pressure sensor with linear fitting method
Authors: Han Xiangguang , Zhao Libo , Wang Jiuhong , Wang Li , Huang Mimi , Chen Cuilan , Yang Ping , Li Zhikang , Zhu Nan , Wang Songli , Yan Xin , Wang Yonglu , Wang Hongyan , Wu Yongshun , Chen Yao , Jiang Zhuangde 
Published: February 2021

Abstract
A high-accuracy differential resonant pressure sensor with two similar resonators is proposed using the linear fitting method to guarantee its output linearity without polynomial compensation. Results reveal that the nonlinearity of the differential resonant pressure sensor is largely dependent on the tensile/compressive sensor pressure–stress ratio c when two similar resonators are used separately as compressive and tensile elements. Nonlinearity decreases sharply with an appropriate ratio c. A theoretical model is proposed to obtain minimal nonlinearity and shows satisfactory agreement with the simulation results. The impact factors of ratio c are analyzed to facilitate adjustments with the designed value. Moreover, micromachining methods are used to fabricate sensing chips. Experiment results show that the nonlinearity and measurement sensitivity of the proposed differential resonant pressure sensor are ±0.02% FS and 35.5 Hz kPa−1 with the linear fitting method in a pressure range of 0–200 kPaA and temperature range of −40 °C to +40 °C. The differential linear fitting method largely decreases compensation complexity without polynomial fitting for high-precision pressure measurement.
Facile depositing strategy to fabricate a hetero-affinity hybrid film for improving gas-sensing performance
Authors: Ye Zongbiao , Yang Wenyao , Yuan Zhen , Zhang Kun , Tai Huiling 
Published: February 2021

Abstract
A novel co-spray method was proposed to fabricate a reduced graphene oxide (rGO)-poly (3-hexylthiophene) (P3HT) hybrid sensing device utilizing immiscible solution for ammonia detection at room temperature. The spectrum and Scanning Electron Microscopy (SEM) results revealed uniformly crimped morphology and favorable π-π interaction for the hybrid film. The hybrid film-based sensor showed obviously enhanced ammonia sensing performance, such as increased response, reduced response time, and reinforced sensitivity, in comparison to bare rGO, P3HT, and traditional rGO/P3HT layered film-based sensors, which could be attributed to an adsorption energy barrier and the p-n heterojunction effect. The synergetic strengthened sensing mechanism is discussed. Meanwhile, recovery ratio was introduced to evaluate the abnormal baseline drift induced high-response behavior. The excellent sensing properties of the hybrid sensor indicate that the co-spray method could be an alternative process for the preparation of hetero-affinity hybrid films or functional devices.