bluuebunny/crossref_metadata_2025_split huggingface dataset:
Penyuluhan Diabetes Mellitus Di Puskesmas Rawat Inap Sukaraja Bandar Lampung
Authors: Hazni Rian , Gustiawan Ricki , Zulfian Zulfian , Lestari Sri Maria Puji , Arania Resti , Sudiadnyani Ni Putu 
Published: February 2021

ABSTRAK Menurut World Health Organization (WHO) tahun 2011 jumlah penderita diabetes melitus di dunia 200 juta jiwa, Indonesia menempati urutan keempat terbesar dalam jumlah penderita diabetes melitus di dunia setelah India, Cina,dan Amerika Serikat. Pada tahun 2011,terdapat sekitar 5,6 juta penduduk Indonesia yang mengidap diabetes mellitus. Sementara itu di Dinas Kesehatan Provinsi Lampung tercatat bahwa pada tahun 2014 persentase penderita DM tipe II sejumlah 1,5% per 100.000 atau sebanyak 5.560. Tujuan dari kegiatan ini adalah untuk meningkatkan pengetahuan akan pentingnya menjaga kesehatan untuk mencegah terjadinya Diabetes Mellitus. Metode yang digunakan dalam kegiatan ini yaitu penyuluhan kepada masyarakat yang mengunjungi Puskesmas Rawat Inap Sukaraja Bandar Lampung. Pelaksanaan kegiatan dibantu oleh mahasiswa FK Universitas Malahayati Bandar Lampung pada 22 Desember 2020. Hasil dari kegiatan ini adalah meningkatnya pengetahuan masyarakat sehingga dapat disimpulkan bahwa penyuluhan pada masyarakat sangat efektif. Kata Kunci: Penyuluhan, Diabetes Melitus, Masyarakat ABSTRACT According to the World Health Organization (WHO) in 2011 the number of diabetes mellitus sufferers in the world was 200 million people, Indonesia was fourth in the number of diabetes mellitus sufferers in the world after India, China and the United States. In 2011, there were approximately 5.6 million Indonesians who had diabetes mellitus. Meanwhile in the Lampung Provincial Health Office, it was recorded that in 2014 the proportion of people with type II DM was 1.5% per 100,000 or as much as 5,560. The purpose of this activity is to increase knowledge about maintaining health to prevent Diabetes Mellitus. The method used in this activity was counseling to the public who visited the Sukaraja Bandar Lampung Puskesmas. Implementation of activities assisted by students of FK Malahayati University in Bandar Lampung on December 22, 2020. The result of this activity is public knowledge so it can be ignored that community education is very effective. Keywords: Counseling, Diabetes Mellitus, community
Naturalized Epistemology and the Law of Evidence: Methodological Reflections
Authors: Pardo Michael S. 
Published: February 2021

<span lang="EN-US">This paper discusses Ronald Allen’s article, <em>Naturalized Epistemology and the Law of Evidence Revisited</em>, and reflects on how epistemology can contribute to our understanding of the evidentiary proof process. I first situate Allen’s critique of recent philosophical scholarship, distinguishing between general theoretical accounts of proof (including the theory that Allen and I have defended), on one hand, and the applications of specific epistemological concepts or issues to law, on the other. I then present a methodological picture that diverges in some respects from the one that emerges from Allen’s critique. In discussing this alternative methodological picture, I explain how epistemology can contribute to legal evidence and proof while avoiding the problems that Allen identifies.</span>
¿Debe probarse el odio? Consideraciones acerca de la sentencia del caso Diana Sacayán
Authors: Manrique María  Laura 
Published: February 2021

<span lang="ES">En este trabajo analizo <em>críticamente</em> la sentencia del ´caso Sacayán´. Este caso es relevante porque, entre otras cosas, aplica por primera vez en la Argentina el agravante de odio a la identidad de género al homicidio cometido contra una persona travesti, Diana Sacayán. Por otra parte, también sugiero que la distinción entre delitos de odio y delitos odiosos puede ser de utilidad para entender el rechazo que nos generó este hecho pero que ello es independiente de si el hecho fue cometido por odio o no.</span>
Undergraduate Paramedic Students’ Experience of Paramedic Tutors Teaching Public Health
Authors: Sendall Marguerite Claire , Ng Athena , McCosker Laura 
Published: February 2021

Introduction Previous studies have shown teaching public health in medical courses improves students’ analytical, problem-solving and communication skills. However, little research to date has shown if public health teaching is helpful to paramedic students. The aim of this study was to examine if having paramedic tutors teach public health had a positive effect on students’ learning and interest in public health. Methods 184 second-year paramedic students at an Australian university completed a printed survey and provided feedback about their learning experience. Students answered multiple choice and open-ended questions about whether their understanding of a public health subject was improved by having a paramedic tutor, and if having different tutors each week affected students’ learning. Results Most students reported their understanding of public health improved when the subject was taught by a paramedic tutor and when paramedic scenario examples were included in teaching. Nearly half felt having different tutors each week made learning difficult. The following themes emerged from student narratives: the relevance of public health to their career; an improved understanding of public health; a realisation about the importance of public health; difficulties presented by an inconsistent teaching style; and poor follow-up and conflicting advice. Conclusion Teaching public health from a paramedic perspective enabled students to understand the relevance of paramedic practice and the role paramedics play in the public health system. Having the same paramedic tutor teaching each week helped students understand the relationship between public health and paramedic practice.
Refining Operational Vertical Mobility
Authors: Sean McKay  , James Johnston  , Greg Smith  , Dominick Briganti  , Bryan Howel  , Ditzel Ricky , Will Gambino  , Jonathan Johnson  , Greg Smith  , Andy Schrader  
Published: February 2021

Environmental hazards have an unrecognized and unmet influence on operations. The mistranslation of vertical access and rescue customs and practices, to an environment with uncertain and unrecognizable hazards, can lead to catastrophic failure. Application of these customs and practices to meet the complex operational constraints and environmental hazards central to high-hazard mission sets, has persisted and confused operational vertical rescue teams. Improvised approaches, using minimal but readily available equipment, can close gaps between theory and practice and between discrete concepts in a continuously evolving environment. This paper addresses existing gaps in operational vertical response utilizing a context-specific approach similar to the authors of the original Tactical Combat Casualty Care (TCCC) project published in the 1996 supplement of Military Medicine (Butler FK, 1996).

A pragmatic framework is introduced, which has been evolving for the past 10 years within USSOCOM, Federal special operations teams, and municipal special response elements termed Operational Vertical Mobility (OVM). Operational Vertical Mobility (OVM) creates an adaptable model within high-hazard vertical response in the same manner that TCCC disrupted prehospital tactical medicine (Butler FK Jr, 2007). Since normative traditional civilian vertical practices do not translate well into the context of a Volatile, Uncertain, Complex, Ambiguous, Threat containing, and Time-compressed (VUCA-T2) environment, OVM reframes vertical response key performance parameters (KPP’s) in opposition to traditional design principles. OVM promotes creating theories out of practice rather than forcing theories into practice. In order to appraise the key performance parameters of verticality within a VUCA-T2 environment, a panel of practitioners with expertise across multiple vertical disciplines and specialized units analyzed relevant guidelines, principles, industry recommendations, nonlinear sciences, and high reliability organizational characteristics for successful operational application.
Sumber Tenaga, Komunikasi, Usia, Lama Kerja Dan Pelatihan Perawat Dapat Meningkatkan Pelaksanaan Perawatan Bayi Prematur Di Ruang Perinatologi
Authors: Julianti Erna , Waluyanti Fajar Tri , Dekania Alleni 
Published: February 2021

Kompleksitas perawatan bayi yang intensif menyebabkan ada perawatan rutin yang terlewatkan sehingga dapat memperpanjang lama perawatan, risiko rawat ulang, meningkatkan komplikasi bayi, dan menurunkan kepuasan orang tua. Penelitian cross sectional ini bertujuan untuk mengidentifikasi faktor-faktor yang berhubungan dengan pelaksanaan perawatan bayi prematur di ruang Perinatologi. Teknik consecutive sampling dilakukan untuk memilih 59 perawat yang merawat bayi prematur di ruang Perinatologi Rumah Sakit Jakarta. Analisis dilakukan secara univariat,dan bivariate. Uji statistik yang digunakan adalah uji pearson dan regresi linear. Hasil analisis didapatkan bahwa ada hubungan yang signifikan antara sumber tenaga perawat, komunikasi, usia, lama kerja perawat, dan pelatihan dengan pelaksanaan perawatan bayi prematur dengan p Value 0,014, 0,004, <0,001, <0,001, <0,001. Bagi pelayanan keperawatan dapat menjadi evaluasi terhadap kinerja perawat untuk meningkatkan kualitas perawatan bayi prematur
Pengembangan Learning Card untuk meningkatkan kerja sama tim dan pengetahuan mahasiswa: A Literature Review
Authors: Pattimura Nastain Abubakar , Rosa Elsye Maria 
Published: February 2021

Penggunaan Learning Card bergambar bertujuan untuk mempermudah mahasiswa memberikan asosiasi terhadap konsep dan materi sehingga gambar yang didapatkan mahasiswa dalam memunculkan ide-ide yang kreatif. Kartu tendang bergambar diharapkan mampu meningkatkan mahasiswa kemampuan spasial dan visual siswa. Tujuan dari Literature Review ini untuk melakukan review terhadap artikel-artikel yang meneliti tentang Pengembangan Learning Card terhadap Peningkatan Kerja Sama Tim dan Pengetahuan Mahasiswa. Data yang digunakan berasal dari jurnal yang berisikan tentang konsep yang diteliti. Proses pengumpulan data dilakukan dengan penyaringan dari 17.071 sumber literatur menjadi 7 literatur berdasarkan kriteria yang ditentukan oleh Penulis dari setiap jurnal yang diambil. Adapun kriteria yang dimaksud meliputi tahun sumber literatur yang diambil mulai tahun 2016 sampai dengan 2019, kesesuaian keyword penulisan, keterkaitan hasil penulisan dan pembahasan. Strategi dalam pengumpulan jurnal berbagai literatur dengan menggunakan situs jurnal yang sudah terakreditasi seperti Google Scholar, Science Direct dan juga BMC Medical Education. Cara penulisan yang efektif untuk setting jurnal dengan memasukkan kata kunci sesuai judul Penulisan seperti “Learning Card AND Teamwork AND Knowledge. Pada kartu Learning merupakan kartu yang berisikan kata kunci dalam pembelajaran yang digunakan mahasiswa dalam menyusun solusi, konsep dan pemecahan masalah baik secara runut dan sistematis.
Pengaruh Peran Tenaga Kesehatan, Peran Keluarga, Kondisi Kesehatan Fisik, Dan Motivasi Terhadap Kecemasan Pada Ibu Menopause
Authors: Wati Mega , Yani Hida 
Published: February 2021

Kecemasan menjelang menopause merupaka suatu bentuk kekhawatiran akibat adanya perubahan-perubahan, baik dari segi fisik maupun psikis, dimana ditandai dengan adanya gejala-gejala yang muncul dari segi kognitif, afektif, somatik, dan motorik. Kecemasan ibu saat menopause akan menimbulkan masalah dalam kehidupan seksual suami istri, gejala-gejala fisik dan psikologi seperti keringat berlebihan dan perasaan tidak berguna karena tidak bisa melahirkan anak lagi. Tujuan penelitian ini untuk mengetahui pengaruh peran tenaga kesehatan, peran keluarga, kondisi lingkungan fisik dan motivasi terhadap kecemasan ibu menopause di Desa Pagarawan Tahun 2018. Desain penelitian menggunakan cross sectional. Metode analisis menggunakan Smart PLS 2.0 dan dan SPSS 18. Populasi penelitianibu menopause sebanyak 68 orang. Hasil pengujian hipotesis dengan Structural Equation Model (SEM) dengan metode smartPLS menghasilkan temuan penelitian yaitu peran tenaga kesehatan (17,02%), peran keluarga (11,79%), kondisi kesehatan fisik (26,18%) dan motivasi (26,29%). Pengaruh langsung kecemasan ibu menopause sebesar 81,28% dan pengaruh tidak langsung sebesar 1,44%. Total pengaruh langsung dan tidak langsung kecemasan ibu menopause sebesar 82,72%. Motivasi merupakan faktor dominan yang sangat mempengaruhi kecemasan ibu menopause. Peneliti menyarankan agar seluruh sektor bekerja sama untuk memotivasi ibu mulai dari persiapan premenopause hingga ibu bisa beradaptasi dengan masa menopause.
Metformin-Enhanced Cardiac AMP-Activated Protein Kinase/Atrogin-1 Pathways Inhibit Charged Multivesicular Body Protein 2B Accumulation in Ischemia–Reperfusion Injury
Authors: Li Tian , Yin Yue , Mu Nan , Wang Yishi , Liu Manling , Chen Mai , Jiang Wenhua , Yu Lu , Li Yan , Ma Heng 
Published: February 2021

Background: Cardiac autophagic flux is impaired during myocardial ischemia/reperfusion (MI/R). Impaired autophagic flux may exacerbate MI/R injury. Charged multivesicular body protein 2B (CHMP2B) is a subunit of the endosomal sorting complex required for transport (ESCRT-III) complex that is required for autophagy. However, the reverse role of CHMP2B accumulation in autophagy and MI/R injury has not been established. The objective of this article is to elucidate the roles of AMP-activated protein kinase (AMPK)/atrogin-1 pathways in inhibiting CHMP2B accumulation in ischemia–reperfusion injury.Methods: Male C57BL/6 mice (3–4 months) and H9c2 cardiomyocytes were used to evaluate MI/R and hypoxia/reoxygenation (H/R) injury in vivo and in vitro, respectively. MI/R was built by a left lateral thoracotomy and occluded the left anterior descending artery. H9c2 cells were firstly treated in 95% N2 and 5% CO2 for 15 h and reoxygenation for 1 h. Metformin (100 mg/kg/d) and CHMP2B (Ad-CHMP2B) transfected adenoviruses were administered to the mice. The H9c2 cells were treated with metformin (2.5 mM), MG-132 (10 μM), bafilomycin A1 (10 nM), and compound C (20 μM).Results: Autophagic flux was found to be inhibited in H/R-treated cardiomyocytes and MI/R mice, with elevated cardiac CHMP2B accumulation. Upregulated CHMP2B levels in the in vivo and in vitro experiments were shown to inhibit autophagic flux leading to the deterioration of H/R-cardiomyocytes and MI/R injury. This finding implies that CHMP2B accumulation increases the risk of myocardial ischemia. Metformin suppressed CHMP2B accumulation and ameliorated H/R-induced autophagic dysfunction by activating AMPK. Activated AMPK upregulated the messenger RNA expression and protein levels of atrogin-1, a muscle-specific ubiquitin ligase, in the myocardium. Atrogin-1 significantly enhanced the interaction between atrogin-1 and CHMP2B, therefore, promoting CHMP2B degradation in the MI/R myocardium. Finally, this study revealed that metformin-inhibited CHMP2B accumulation induced autophagic impairment and ischemic susceptibility in vivo through the AMPK-regulated CHMP2B degradation by atrogin-1.Conclusion: Impaired CHMP2B clearance in vitro and in vivo inhibits autophagic flux and weakens the myocardial ischemic tolerance. Metformin treatment degrades CHMP2B through the AMPK-atrogin-1-dependent pathway to maintain the homeostasis of autophagic flux. This is a novel mechanism that enriches the understanding of cardioprotection.
Impact of the Anomalous Latent Heat Flux Over the Kuroshio Extension on Western North American Rainfall in Spring: Interannual Variation and Mechanism
Authors: Long Jingchao , Liu Chunlei , Liu Zifeng , Xu Jianjun 
Published: February 2021

The Kuroshio and its extension (KE) significantly influences regional climate through meridional heat transport from the tropical ocean. In this study, the observational and reanalysis datasets are used to investigate the impact of the latent heat flux (LHF) over the KE region on downstream rainfall and the underlying mechanism. The result shows a “seesaw” structure in rainfall anomaly, dominating the Western Canada and the southwestern North America with a correlation coefficient of 0.77 between the two modes. In strong LHF years, strengthened LHF favors to enhance precipitation in the Western Canada and reduce that in the southwestern North America. This is primarily associated with an anomalous cyclonic circulation over the KE region, which enhances southwesterly precipitation and latent heating in the middle troposphere. The heating excites an anomalous cyclonic circulation to its west and an anticyclonic circulation to its east, helping to reinforce the existing anomalous cyclonic circulation in turn and form a positive feedback. The conditions associated with La Niña events favor to above processes. To the upper troposphere, the deepened anomalous cyclonic circulation due to enhanced eddy activities and atmospheric baroclinic instability over the KE strengthens subtropical westerly jet stream and thereby extends eastward on the 200 hPa level. Correspondingly, an elongated zonally lower level cyclonic circulation anomaly across the North Pacific leads to a moisture convergence in the Western Canada, which is mainly resulted from the anomalous positive vorticity advection over the left side of the exit region of the jet stream. The opposite circumstance occurs in weak LHF years, presenting an opposed anomalous circulation and rainfall pattern.
Depression-/Anxiety-Like Behavior Alterations in Adult Slit2 Transgenic Mice
Authors: Huang Guilan , Wang Sheng , Yan Jie , Li Changxi , Feng Jianwen , Chen Qi , Zheng Xiaomeng , Li Huimin , He Yajun , Young Andrew J. , Li Haobin , Li Weidong , Li Jiangchao , Wang Lijing 
Published: February 2021

Background: Slit2 is a member of the Slit family of secreted glycoproteins that plays highly conserved roles in neuronal axon guidance and cellular migration. Our previous experimental results showed Alzheimer's disease-like alterations and increased permeability of the blood–brain barrier in Slit2-overexpressing transgenic (Slit2-Tg) mice aged 8–9 months. Nevertheless, relatively little is known about behavioral alterations in adult Slit2-Tg mice (2–6 months of age). To observe the age-related behavioral effects of Slit2 overexpression in adult mice, we performed a battery of behavioral tests with adult Slit2-Tg mice at 2–6 months of age.Results: The body weight of Slit2-Tg mice was lower than that of the wild-type mice from 15 weeks of age. Compared with the control mice, depression-like behaviors were found in Slit2-Tg mice from 15 to 21 weeks of age in the sucrose preference test, although Slit2-Tg mice were hyperactive in the tail suspension test. The anxiety-like behaviors were found in Slit2-Tg mice in the open field test, as well as increased locomotor activity. The anxiety-like behaviors were also found in adult Slit2-Tg mice in the elevated plus maze. Compared to wild-type mice at 23 weeks old, impairment of the hippocampal neurons were found in Slit2-Tg mice at the same age in hematoxylin–eosin staining (H&amp;E), including some eccentric dispersion and expansion of neuronal bodies. In addition, the messenger RNA (mRNA) expression of TNF-α was elevated in the hippocampus of adult Slit2-Tg mice.Conclusions: Slit2 overexpression causes depression-/anxiety-like behaviors in adult mice that may be related to an increase in inflammatory factors and damage to hippocampal neurons.
Imaging Identification and Prognosis of the Distal Internal Carotid Artery With Near and Complete Occlusion After Recanalization
Authors: Sun Tao , Wang Chao , Han Mengtao , Wang Fei , He Yiming , Wang Yunyan , Li Xingang , Wang Donghai 
Published: February 2021

Background and Purpose: Previous studies have mainly focused on treatment strategies and clinical outcomes for internal carotid artery near occlusion (ICANO) and internal carotid artery complete occlusion (ICACO). However, reports on the morphological changes of distal internal carotid artery (ICA) after recanalization are scarce. This study aimed at illustrating identifying features, assessing prognosis of the distal ICA after recanalization, and exploring best practices for treatment for ICANO and ICACO.Materials and Methods: We retrospectively studied the clinical characteristics of 57 patients with ICANO or ICACO who underwent surgical recanalization. The clinical data, angiographic morphology, technical successful rate, perioperative complications, and the lumen changes of distal ICA before and after successful recanalization were analyzed.Results: Fifty-two patients who achieved successfully recanalization were studied. Based on the postoperative lumen diameter changes in the distal ICA, 19 cases were classified as distal-dilatation and the remaining 33 as distal-narrowness. Patients in the distal-narrowness group mostly had ICACO (21.1 vs. 54.5%) and were men (68.4 vs. 93.9%). In the distal-narrowness group, the lumen of the distal ICA recovered to normal in 32 of the 33 patients during the follow-up period. Of the 32 patients reviewed, the ICA of 28 patients dilated back to normal after 1 week of surgery; the ICA of remaining patients 4 dilated 2 weeks postoperatively.Conclusions: Narrowness of the distal ICA after hybrid recanalization was more prevalent in male patients with ICACO. Homogeneous stenosis of the whole course of the distal ICA is a low-perfusion narrowness which does not require intervention and will spontaneously recover after successful recanalization with an increase in the forward flow.
Neural Mechanisms of Hearing Recovery for Cochlear-Implanted Patients: An Electroencephalogram Follow-Up Study
Authors: Wang Songjian , Lin Meng , Sun Liwei , Chen Xueqing , Fu Xinxing , Yan LiLi , Li Chunlin , Zhang Xu 
Published: February 2021

BackgroundPatients with severe profound hearing loss could benefit from cochlear implantation (CI). However, the neural mechanism of such benefit is still unclear. Therefore, we analyzed the electroencephalogram (EEG) and behavioral indicators of auditory function remodeling in patients with CI. Both indicators were sampled at multiple time points after implantation (1, 90, and 180 days).MethodsFirst, the speech perception ability was evaluated with the recording of a list of Chinese words and sentences in 15 healthy controls (HC group) and 10 patients with CI (CI group). EEG data were collected using an oddball paradigm. Then, the characteristics of event-related potentials (ERPs) and mismatch negative (MMN) were compared between the CI group and the HC group. In addition, we analyzed the phase lag indices (PLI) in the CI group and the HC group and calculated the difference in functional connectivity between the two groups at different stages after implantation.ResultsThe behavioral indicator, speech recognition ability, in CI patients improved as the implantation time increased. The MMN analysis showed that CI patients could recognize the difference between standard and deviation stimuli just like the HCs 90 days after cochlear implantation. Comparing the latencies of N1/P2/MMN between the CI group and the HC group, we found that the latency of N1/P2 in CI patients was longer, while the latency of MMN in CI users was shorter. In addition, PLI-based whole-brain functional connectivity (PLI-FC) showed that the difference between the CI group and the HC group mainly exists in electrode pairs between the bilateral auditory area and the frontal area. Furthermore, all those differences gradually decreased with the increase in implantation time.ConclusionThe N1 amplitude, N1/P2/MMN latency, and PLI-FC in the alpha band may reflect the process of auditory function remodeling and could be an objective index for the assessment of speech perception ability and the effect of cochlear implantation.