bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ontogeny of a subtidal point bar in the microtidal Venice Lagoon (Italy) revealed by three‐dimensional architectural analyses
Authors: Bellizia Elena , Donnici Sandra , Madricardo Fantina , Finotello Alvise , D’Alpaos Andrea , Ghinassi Massimiliano 
Published: November 2021

AbstractSedimentological and architectural features of meandering subtidal channels are relatively unexplored, and their deposits are commonly investigated based on facies models set up for intertidal meandering channels. The Venice Lagoon (northern Adriatic Sea, Italy) is affected by a micro‐tidal regime and hosts a dense network of active and buried tidal channels. It represents an excellent natural laboratory to improve the current knowledge on subtidal meander morphodynamics and related deposits. In this study, the integration of high‐resolution geophysical images and core data allows reconstruction of the architectural three‐dimensional model of a meandering subtidal palaeochannel, which is buried below a modern subtidal flat. The study palaeochannel was 35 m wide and 3 m deep, and formed three adjacent meander bends and related point bars. A detailed three‐dimensional architectural reconstruction was carried out for deposits associated with one of these meander bends, that was crossed by a minor, low‐sinuosity channel with two minor bank‐attached bars. This reconstruction highlights that the study point bar has a horseshoe shape, which arose from the onset of bar accretion from an already‐sinuous channel. Reconstructed growth stages of the studied bends show that point‐bar accretion can follow different styles of planform transformation, also experiencing simultaneously landward (or seaward) deposition according to the dominant flow direction (i.e. local tidal asymmetry). The analyses show that planform transformations occurred in parallel with elevation changes of the related channel thalweg, which shaped pools with geometry varying with the radius of curvature of the bend. The present study highlights the relevance of high‐resolution three‐dimensional reconstructions to link palaeomorphodynamic processes with related sedimentary products.
Biomechanical responses of Nordic walking in people with Parkinson's disease
Authors: Leal‐Nascimento Antonio Henrique , da Silva Edson Soares , Zanardi Ana Paula Janner , Ivaniski‐Mello André , Passos‐Monteiro Elren , Martinez Flávia Gomes , Rodrigo de Carvalho Alberito , Baptista Rafael Reimann , Peyré‐Tartaruga Leonardo Alexandre 
Published: November 2021

In healthy adults, Nordic walking (NW) is known to increase the external mechanical energy fluctuations, though the external work is unaltered due to an improved pendulum‐like recovery in comparison with free walking (FW). We aimed to compare mechanical, pendulum‐like, and spatiotemporal parameters of gait at different speeds with and without NW poles in people with Parkinson's disease and healthy controls. The study included 11 people (aged 65.6 ± 7.0 years) with idiopathic Parkinson's disease, scoring between 1 and 1.5 on the Hoehn and Yahr scale (H&Y), and nine healthy controls (aged 70.0 ± 5.6 years). All the people were experienced Nordic walkers. Walking tests were performed at 1.8 km h−1 and 4.7 km h−1, on eight 3D force platforms on a walkway. We found greater pendulum‐like energy recovery (p < 0.05) in the Parkinson group during NW than in FW, while external mechanical work remained similar (p > 0.05). People with Parkinson's disease showed a major increase in vertical and forward energy fluctuations using poles than in healthy controls. In addition, the Parkinson group showed increased stride frequency and reduced stride length compared to controls in the NW and FW conditions. Our findings partly justify the lower walking economy in Parkinson's disease due to reduced pendulum‐like mechanism at commonly used speeds. NW alters gait mechanics similarly in Parkinson group and healthy control, increasing the total mechanical work. Therefore, NW can be a compelling strategy for rehabilitation because of its potential for improving functional mobility, increasing pendulum‐like mechanism in Parkinson's disease.
Categorical Perception of p‐Values
Authors: Rao V. N. Vimal , Bye Jeffrey K. , Varma Sashank 
Published: November 2021

AbstractTraditional statistics instruction emphasizes a .05 significance level for hypothesis tests. Here, we investigate the consequences of this training for researchers’ mental representations of probabilities — whether .05 becomes a boundary, that is, a discontinuity of the mental number line, and alters their reasoning about p‐values. Graduate students with statistical training (n = 25) viewed pairs of p‐values and judged whether they were “similar” or “different.” After controlling for several covariates, participants were more likely and faster to judge p‐values as “different” when they crossed the .05 boundary (e.g., .046 vs. .052) compared to when they did not (e.g., .026 vs. .032). This result suggests a categorical perception‐like effect for the processing of p‐values. It may be a consequence of traditional statistical instruction creating a psychologically real divide between so‐called statistical “significance” and “nonsignificance.” Such a distortion is undesirable given modern approaches to statistical reasoning that de‐emphasize dichotomizing the p‐value continuum.
The Right to Change Co‐Producing Ethnographic Animation with Indigenous Youth in Amazonia
Authors: Morelli Camilla 
Published: November 2021

AbstractThis article explores the use of ethnographic animation as a method to engage Indigenous youth actively in the production and representation of knowledge, producing research that not only examines social change, but also establishes pathways for change driven by participants themselves. Drawing on a recent collaboration with a professional animator, an Indigenous artist, and young Matses migrants in Amazonian Peru, I discuss how ethnographic animation can open up a space for Indigenous youth who feel radically unheard and unseen by wider society to discuss key challenges they face, while producing tangible outputs (animated films) to gain a sense of wider recognition through forms of self‐representation.
Adaptive Virtual Reality Exergame: Promoting Physical Activity Among Workers
Authors: Stranick Thomas , Lopez Christian 
Published: November 2021

AbstractThis work presents a virtual reality (VR) Exergame application designed to prevent work-related musculoskeletal disorders (WMSDs). Moreover, to help adapt the tasks of the exergame, a machine learning model that predicts users’ exercise intensity level is presented. WMSDs are an important issue that can have a direct economic impact to an organization. Exercise and stretching is one method that can benefit workers and help prevent WMSDs. While several applications have been developed to prevent WMSDs, most of them suffer from a lack of immersivity or they just focus on education and not necessarily on helping workers warm-up or stretch. In light of this, an Exergame application that leverages VR and Depth-sensor technology to help provide users with an immersive first-person experience that engages them in physical activities is introduced in this work. The objective of the Exergame is to motivate users to perform full-body movements in order to pass through a series of obstacles. While in the game, users can visualize their motions by controlling the virtual avatar with their body movements. It is expected that this immersivity will motivate and encourage the users. Initial findings show the positive effects that the base exergame has on individuals’ motivation and physical activity. The results indicate that the application was able to engage individuals in low-intensity exercises that produced significant and consistent increases in their heart rate. Lastly, the results show that the machine learning model predicted users’ exercise activity level with an accuracy of 76.67%.
Effect of Graphene Nanoplatelets Reinforcement on Grindability of Zirconium Diboride Ceramics
Authors: Shanbhog Nagaraj , Arunachalam N. , Bakshi Srinivasa R. 
Published: November 2021

Abstract
The effect of graphene nanoplatelets (GNPS) on the grindability of GNP reinforced ZrB2 was studied using a resin bonded diamond grinding wheel under dry and wet conditions. A comparative study of grinding forces was performed at selected wheel surface speeds and depths of cut for surface grinding. ZrB2-GNP showed lower normal grinding forces due to the improved fracture toughness and reduced hardness. The presence of GNP reinforcement in ZrB2 resulted in lower tangential forces and reduced specific grinding energy due to the role of GNP as a solid lubricant. The measured forces showed a good correlation with the micro cutting model for ZrB2 and ZrB2-GNP under dry conditions. The tangential forces showed the same trend as normal forces at different depths of cut and wheel surface speeds for ZrB2 and ZrB2-GNP with average force ratios of 0.3 and 0.35, respectively. The presence of porosity in ZrB2 increased the normal grinding forces during wet grinding. Scanning electron microscope (SEM) images of the grinding chips indicated a mixture of both the ductile mode and the brittle mode of material removal with predominantly brittle fractured chips. Energy-dispersive spectroscopy (EDS) confirmed the presence of GNPs in ZrB2-GNP grinding chips. The topography of the grinding wheel showed higher wheel loading after the dry grinding than that of wet grinding. The wet grinding resulted in relatively lower surface roughness (Ra values) than dry grinding.
Method for Determining Adiabatic Film Effectiveness in Presence of Thermal Boundary Layer
Authors: Parker James , Povey Thomas 
Published: November 2021

Abstract
In this paper, we present a new method for determining adiabatic film effectiveness in film cooling experiments with nonuniform inlet temperature distributions, in particular the situation of an inlet thermal boundary layer. This might arise in a quasi-steady experiment due to loss of heat from the mainstream flow to the inlet contraction walls, for example. In this situation, the thermal boundary layer would be time-varying. Adiabatic film effectiveness is generally normalized by the difference between mainstream and coolant gas temperatures. Most importantly, these temperatures are generally assumed to be spatially—and, possibly temporally—uniform at the system inlet. In experiments with nonuniform inlet temperature, the relevant hot gas temperature for a particular point of interest on a surface is not easily determined, being a complex function of both the inlet temperature profile and the flow field between the inlet and the point of interest. In this situation, adiabatic film effectiveness cannot be uniquely defined using conventional processing techniques. We solve this problem by introducing the concept of equivalent mainstream effectiveness, a nondimensional temperature for the mainstream that can be used to represent the thermal boundary layer profile at the inlet plane, or the effective temperature of the mainstream gas—which we refer to as the equivalent mainstream temperature—entrained into the mixing layer affecting the wall temperature at a particular point of interest. By using data from two or more time instants during an experiment, we simultaneously solve for equivalent mainstream effectiveness and true adiabatic film effectiveness, that is, the adiabatic film effectiveness that we would measure in an experiment with both steady and uniform inlet temperature. This is an important transformation because the true adiabatic effectiveness has a clear physical interpretation and is a more transportable quantity between systems (comparisons between different experiments, between experiment and computational fluid dynamics (CFD), etc.). The proposed method is experimentally demonstrated using full-surface infrared (IR) thermography measurements of a cooled rotor blade platform, operated in a transonic linear cascade facility at matched engine conditions. Film effectiveness measurements processed in the conventional way suffer from inlet thermal boundary layer effects, rendering them both time-varying (as heat is released to the walls of the tunnel) and, in certain regions, nonphysical in magnitude. The proposed technique renders the same data insensitive to time, and everywhere within physically reasonable limits. By demonstrating independence to the particular (time-varying) inlet temperature profile, we demonstrate the advantages of the proposed technique.
Binding of Gold(III) from Solutions by the [Ag6{S2CN(CH2)6}6] Cluster: Synthesis, Thermal Behavior, and Self-Organization of the Supramolecular Structure of the Double Complex [Au{S2CN(CH2)6}2]2[AgCl2]Cl·2CHCl3 (Role of Secondary Au⋅⋅⋅Cl, Ag⋅⋅⋅S, and Cl⋅⋅⋅Cl Interactions)
Authors: Korneeva E. V. , Novikova E. V. , Loseva O. V. , Smolentsev A. I. , Ivanov A. V. 
Published: November 2021

Abstract
The capability of silver(I) cyclo-hexamethylenedithiocarbamate to concentrate gold(III) from solutions characterized by a high level of salinity (5.15 M NaCl) into the solid phase has been established. The double chloroform-solvated Au(III)–Ag(I) complex [Au{S2CN(CH2)6}2]2[AgCl2]Cl·2CHCl3 (I) was preparatively isolated as an individual form of binding of [AuCl4]– anions. The composition of the ionic structural units of compound I indicates that gold(III) binding from a solution to the solid phase is accompanied by the complete redistribution of the HmDtc ligands between the coordination spheres of Ag(I) and Au(III). Complex I characterized by IR spectroscopy, simultaneous thermal analysis, and X-ray structure analysis (CIF file CCDC no. 2051654) exhibits the supramolecular structure containing two oppositely charged pseudo-polymeric subsystems. Complex cations [Au{S2CN(CH2)6}2]+ and anions [AgCl2]– (in a ratio of 2 : 1) form a complicatedly organized cation-anionic pseudo-polymeric ribbon ({[Au(HmDtc)2]⋅⋅⋅[AgCl2]⋅⋅⋅[Au(HmDtc)2]}+)n due to secondary interactions Ag⋅⋅⋅S (3.2613 Å) and Au⋅⋅⋅Cl (3.2765 Å). The pseudo-polymeric ribbon consists of two rows of cations and a row of anions. The outer-sphere chloride ions combine the solvate chloroform molecules by two equivalent hydrogen bonds Cl⋅⋅⋅H–C yielding anion-molecular triads [Cl3CH⋅⋅⋅Cl⋅⋅⋅HCCl3]–, which are involved in the formation of the supramolecular ribbon due to the secondary Cl⋅⋅⋅Cl interactions (3.4058 Å) between the nonequivalent chlorine atoms of the nearest solvate molecules. The study of the thermal behavior of complex I makes it possible to determine the character of thermolysis and conditions for the quantitative regeneration of bound gold.
Eliciting gastric cancer survivors’ preferences for follow-up services: a discrete choice experiment protocol
Authors: Li Hui-qin , Han Jin-hua , Yuan Hua , Wan Guang-ying , Xue Hui , Zhang Xiu-ying 
Published: November 2021

IntroductionFollow-up care is important for gastric cancer survivors, but follow-up strategies for gastric cancer survivors remain inconsistent, and compliance of gastric cancer survivors with follow-up care is very low. Understanding the needs and preferences of gastric cancer survivors is conducive to developing appropriate and acceptable follow-up strategies, thereby improving patient compliance. Discrete choice experiments can quantify individual needs and preferences. However, to date, there is no discrete choice experiment on the preferences of gastric cancer survivors, and no studies have examined how gastric cancer survivors make choices based on different characteristics of follow-up. This paper outlines an ongoing discrete choice experiment that aims to (1) explore follow-up service-related characteristics that may affect gastric cancer survivors’ choices about their follow-up, (2) elicit how gastric cancer survivors consider the trade-offs among different follow-up service options using discrete choice experiment, (3) determine whether gastric cancer survivors’ needs and preferences for follow-up vary due to the economy, politics, technology and culture in different regions.Methods and analysisSix attributes were developed through a literature review, semistructured interviews and experts and focus group discussions. A fractional factorial design was used to evaluate the interaction between attributes. A multiple logit model will be used to understand the trade-off between the follow-up characteristics of gastric cancer survivors. A mixed logit model will be used to explore the willingness to pay and uptake rate of gastric cancer survivors for follow-up attributes and further explore the preferences of different groups.Ethics and disseminationThis study was approved by the ethics committee of the School of Nursing, Jilin University. The results of this study will be shared through online blogs, policy briefs, seminars and peer-reviewed journal articles and will be used to modify the current strategy of gastric cancer survivors’ follow-up services according to economic development and regional culture.
Characteristics of Chinese patients with genetic CJD who have E196A or E196K mutation inPRNP: comparative analysis of patients identified in the Chinese National CJD Surveillance System
Authors: Shi Qi , Xiao Kang , Chen Cao , Zhou Wei , Gao Li-Ping , Wu Yue-Zhang , Wang Yuan , Hu Chao , Gao Chen , Dong Xiao-Ping 
Published: November 2021

ObjectiveTwo different mutations at codon 196, namely E196A and E196K, have been reported to be related to genetic Creutzfeldt-Jakob disease (CJD). We aimed to comparatively analyse the features of Chinese patients with these two mutations from the CJD surveillance system in China.Design and settingComparative analysis of patients identified via the Chinese National CJD Surveillance System during the period 2006–2020.Participants16 Chinese patients with genetic CJD with E196A mutation and 5 with E196K mutation.MethodsNeurological examination, EEG and MRI, western blot, gene sequence, and RT-QuIC.ResultsThe age of onset of E196K genetic CJD cases (median of 61 years) was older than the E196A cases (median of 67 years). Generally, these two subtypes of genetic CJD were more like sporadic Creutzfeldt-Jakob disease (sCJD) clinically. The E196A cases showed more major symptoms, while those of E196K cases were restricted to dementia and mental problems. During progression, more sCJD-associated symptoms and signs gradually appeared, but none of the E196K cases showed cerebellum and visual disturbances. Typical periodic sharp wave complexes on MRI were recorded in 25% of E196A cases but not in E196K cases. sCJD-associated abnormalities on MRI, positive cerebrospinal fluid (CSF) 14-3-3 and increased CSF total tau were observed frequently, ranging from two out of three cases to four out of five cases, without a difference. Positive CSF RT-QuIC was detected in 37.5% (6 of 16) of E196A cases and 60% (3 of 5) of E196K cases. The duration of survival of E196K cases (median of 4.5 months) was shorter than the E196A cases (median of 6.5 months). Moreover, female cases and cases with young age of onset (<60 years) in E196A displayed longer survival time than male patients and cases with older age of onset (≥60 years).ConclusionsThis is the largest comprehensive report of genetic CJD with mutations at codon 196 to date, describing the similarity and diversity in clinical and laboratory tests between patients with E196A and with E196K mutations.
Diversion-p64: results from an international, prospective, multicenter, single-arm post-market study to assess the safety and effectiveness of the p64 flow modulation device
Authors: Bonafe Alain , Perez Marta Aguilar , Henkes Hans , Lylyk Pedro , Bleise Carlos , Gascou Gregory , Sirakov Stanimir , Sirakov Alexander , Stockx Luc , Turjman Francis , Petrov Andrey , Roth Christian , Narata Ana-Paula , Barreau Xavier , Loehr Christian , Berlis Ansgar , Pierot Laurent , Miś Marcin , Goddard Tony , Clifton Andy , Klisch Joachim , Wałęsa Cezary , Dall’Olio Massimo , Spelle Laurent , Clarencon Frédéric , Yakovlev Sergey , Keston Peter , Nuzzi Nunzio Paolo , Dima Stefanita , Wendl Christina , Willems Tine , Schramm Peter 
Published: November 2021

BackgroundThe use of flow diversion to treat intracranial aneurysms has increased in recent years.ObjectiveTo assess the safety and angiographic efficacy of the p64 flow modulation device.MethodsDiversion-p64 is an international, prospective, multicenter, single-arm, study conducted at 26 centers. The p64 flow modulation device was used to treat anterior circulation aneurysms between December 2015 and January 2019. The primary safety endpoint was the incidence of major stroke or neurologic death at 3–6 months, with the primary efficacy endpoint being complete aneurysm occlusion (Raymond-Roy Occlusion Classification 1) on follow-up angiography.ResultsA total of 420 patients met the eligibility criteria and underwent treatment with the p64 flow modulation device (mean age 55±12.0 years, 86.2% female). Mean aneurysm dome width was 6.99±5.28 mm and neck width 4.47±2.28 mm. Mean number of devices implanted per patient was 1.06±0.47, with adjunctive coiling performed in 14.0% of the cases. At the second angiographic follow-up (mean 375±73 days), available for 343 patients (81.7%), complete aneurysm occlusion was seen in 287 (83.7%) patients. Safety data were available for 413 patients (98.3%) at the first follow-up (mean 145±43 days) with a composite morbidity/mortality rate of 2.42% (n=10).ConclusionsDiversion-p64 is the largest prospective study using the p64 flow modulation device. The results of this study demonstrate that the device has a high efficacy and carries a low rate of mortality and permanent morbidity.
Extended Thrombolysis In Cerebral Infarction (eTICI) grade 2c: a potential angiographic target for endovascular treatment in acute basilar artery occlusion?
Authors: Chen Luming , Zhao Chenghao , Song Jiaxing , Zi Wenjie , Sang Hongfei , Yuan Junjie , Huang Jiacheng , Li Linyu , Luo Weidong , Fu Xinmin , Zhou Peiyang , Wan Yue , Zeng Guoyong , Xie Dongjing , Gao Fei , Li Fengli , Qiu Zhongming , Yang Qingwu 
Published: November 2021

BackgroundHigher extended Thrombolysis In Cerebral Infarction (eTICI) grades are associated with better clinical outcomes after endovascular treatment (EVT) for proximal intracranial occlusion of the anterior circulation. However, the relationship between eTICI grade and outcomes after EVT in patients with acute basilar artery occlusion (BAO) remains unclear. We aimed to explore which eTICI category was the cut-off correlating with better clinical outcomes in patients with BAO undergoing EVT.MethodsWe included patients treated via EVT from the BASILAR study. Multivariable logistic regression analyses were performed to assess the impact of eTICI grades on 90-day favorable functional outcomes, defined as a modified Rankin Scale (mRS) score of 0–3. Other outcomes were functional independence (mRS 0–2), all-cause mortality, and symptomatic intracranial hemorrhage.ResultsAmong 647 patients treated with EVT, 127 (19.6%), 128 (24.5%), 110 (21.1%), and 282 (54%) patients achieved eTICI grades of 0–2a, 2b, 2c, and 3, respectively. Compared with eTICI grades 0–2a, higher rates of favorable functional outcomes (adjusted OR (aOR) 2.96, 95% CI 1.33 to 6.57, and aOR 7.40, 95% CI 3.63 to 15.09, respectively) were observed for grades 2c and 3, not 2b (aOR 1.93, 95% CI 0.86 to 4.36). The risks of mortality and symptomatic intracranial hemorrhage were also lower for eTICI grades 2c and 3 than for grades 0–2a.ConclusionsAn eTICI grade of 2c/3 may be a target for successful reperfusion after EVT in patients with acute BAO; however, further studies with larger sample sizes and clinical trials are needed.