bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peningkatan Kemampuan Refleksi Peserta Didik dengan Penerapan Model STM Berbasis Google Form
Authors: Masruroh Ana Miftachul , Fadly Wirawan , Faizah Ulinnuha Nur , Anwar Muhamad Khoirul 
Published: December 2021

Penelitian ini bertujuan untuk mengetahui 1) Keterlaksanaan pembelajaran model STM berbasis google form, 2) Keefektivitas model STM berbasis google form dalam meningkatkan kemampuan refleksi peserta didik di SMP Ma’arif 1 Ponorogo, dan 3) Respons peserta didik model STM berbasis google form. Penelitian ini menggunakan rancangan penelitian kuantitatif Quasi Experimental.dengan sampel yang digunakan dalam penelitian ini yaitu peserta didik kelas VII A (kelas eksperimen ) dan VII B (kelas kontrol) yang dipilih dengan menggunakan teknik random sampling. Hasil penelitian menunjukkan bahwa model pembelajaran STM berbasis google form terbukti dapat meningkatkan kemampuan refleksi peserta didik serta dalam proses pembelajaran berjalan dengan baik. Temuan lain dalam penelitian yaitu: 1) proses pembelajran berjalan dengan baik, 2) nilai hasil belajar kelas eksperimen dalam meningkatkan kemampuan refleksi lebih baik daripada kelas konvensional, dan 3) respons peserta didik baik. Saran dalam penelitian yaitu diharapkan untuk menggunakan model STM berbasis google form karena model ini dapat membangun kemampuan refleksi peserta didik dalam kebenaran dan apa yang ditanyakan dalam permasalahan.
An Assessment of an Educational Intervention Program Based on the Health Belief Model for Safer Sex Among Female Sex Workers in Selected Districts of Northern Region of Malawi
Authors: Twizelimana Donatien , Muula Adamson Sinjani 
Published: December 2021

Abstract
Background: Pregnant women are at risk of pregnancy if they have unprotected sex, do not use or poorly use contraceptives in the context of penile-vaginal sex. We therefore developed an educational toolkit based on the Health Belief Model (HBM) to assist FSWs to make informed sexual and reproductive decision for safer sex before and/or after heterosexual encounter with their clients. We evaluated the educational intervention programme among FSWs and other stakeholders (nurses and clinicians).Methods:This was a qualitative operational research. We developed an educational tool kit based on the HBM to aid FSWs to make informed decision for safer sex behaviour. We conducted 10 in-depth interviews (IDIs) to identify the components of the educational tool kit, 5 IDIs for modification and refining the tool, and consequently two Focus Group Discussions (FGDs) for consensus building. This process was done in Mzimba North. After the intervention we conducted 6 FGDs with FSWs and 10 IDIs with nurses and clinicians to evaluate the applicability and feasibility of the intervention among female sex workers (FSWs) in Mzimba North, and Nkhata Bay located in Northern region of Malawi.Results:We observed mixed opinions on the components of the educational toolkit. Female sex workers were eager to understand misinformation and misconceptions on contraceptives, right to justice, effectiveness of contraceptives. Female sex workers requested the inclusion of STIs and HIV prevention and economic empowerment in the toolkit. Overall the toolkit and the educational intervention were relevant, feasible, and applicable among the study participants. Conclusion:While several strategies can be used to facilitate the implementation of the evidence based intervention to improve health, our educational intervention program based on the Health Belief Model for safer sex behaviour among female sex workers was found to be feasible and applicable in our study settings. We believe that the intervention may be helpful to address sexual and reproductive health challenges encountered by FSWs in the study sites and elsewhere.
Evaluation of Cytogenetic Alterations of Toxic Gas Exposed Population of Bhopal Having Chronic Kidney Disease
Authors: Samarth Ravindra M , Tiwari Rajnarayan , Modi Gopesh , Soni Kishor K , Banjare ML , Hasan Sharique Ul , Jain Sanjay 
Published: December 2021

Abstract
The industrial disaster of Bhopal in 1984 resulted in widespread morbidity and mortality in the vicinity of the industry and required long-term surveillance for chronic health effects in those affected by the leakage of gas. Although few cytogenetic studies were undertaken to assess genetic damage in survivors of the disaster, no studies are available on cytogenetic damage of toxic gas-exposed populations having chronic kidney disease (CKD). Thus, the present study aimed to evaluate cytogenetic alterations in chronic kidney disease patients who were exposed to leaked gas and to compare it with those who were not exposed to the leaked gas. The cytogenetic alterations were evaluated through chromosomal aberration analysis and micronuclei assay. The study included 608 study participants divided into four groups based on the history of exposure to the leaked gas and the presence or absence of CKD. The results of the study showed no statistically significant difference in cytogenetic damage between gas-exposed and non-exposed patients of CKD. However, significantly higher cytogenetic damage was observed among gas-exposed participants having CKD as compared to gas-exposed participants free from CKD. Thus, to conclude though the cytogenetic alterations were observed in an exposed group it cannot be solely attributed to the gas exposure and the role of other confounders must also be studied.
Implication of Shoreline and Nearshore Morphological Changes on Sediment Budget of Wave-Dominated Chennai Beach, India
Authors: SHETTY ATEETH , KANKARA R. S. , S. DHANALAKSHMI , S. BUCKLE , S. SUBBURAJ 
Published: December 2021

Abstract
The study examines the shoreline (1990-2019) and nearshore morphological changes (seasonal) to understand the littoral drift and sediment budget variability. Shoreline change rate depicts erosion (-0.06 m/yr) in the northern sector and accretion (+0.12 m/yr) in the southern sector. Seasonal nearshore morphological changes from non-monsoon to monsoon period signifies net erosion (-1.8x10^4 m^3 ) in northern sector and net accretion (+2.5x10^4 m^3) in the southern sector. Although the lost sediment during monsoon is regained in non-monsoon period, the quantity of sediment gain is reduced in areas with human interventions. The results of the investigation depict the dominance of littoral drift towards north from February to October, when wave approach from east-southeast to south-southeast direction and southwards from November to January when the wave direction was from east-northeast to east-southeast. The net longshore sediment transport rate estimated during the study period was 2.6x10^5 m^3/year in the northern sector and 1.5x10^5 m^3/year in the southern sector with higher rate attributed to monsoon than the non-monsoon. Sediment budget results in deciphering the causes of erosion (-1.27×10^4 m^3/yr) in northern sector and accretion (3.91×10^4 m^3/yr) in southern sector in the wave-dominated Chennai beach.
Acupuncture Improves Certain Aspects of Sleep in Hematopoietic Stem Cell Transplantation Patients: a Randomized Controlled Trial
Authors: Iskandarani Sarah El , Sun Lingyun , Li Susan Qing , Pereira Gloria , Giralt Sergio , Deng Gary 
Published: December 2021

Abstract
Background

High-dose chemotherapy followed by hematopoietic stem cell transplantation (HSCT) is associated with a high symptom burden including decrease in sleep quality. We conducted a randomized sham-controlled trial (#NCT01811862) to study the effect of acupuncture on sleep quality during HSCT.
Methods

Adult multiple myeloma patients undergoing inpatient and outpatient autologous HSCT were randomized to receive either true or sham acupuncture once daily for 5 days starting the day after chemotherapy. Sleep onset, total sleep time, sleep efficiency percentage, and sleep-onset latency time were assessed using an Actigraphy Sleep Monitor. A multi-variate regression analysis was conducted to compare the average area-under-the-curve of five acupuncture intervention days for each sleep outcome between groups, adjusted by baseline score and inpatient or outpatient chemotherapy stratum.
Results

Over 32 months, 63 patients were enrolled. Participants undergoing true acupuncture experienced a significant improvement in sleep efficiency when compared to sham (-6.70, 95% CI -13.15, -0.25, p=0.042). Subgroup analysis showed that the improvement is more prominent in the inpatient setting (-9.62, 95% CI -18.76, -0.47, p=0.040). True acupuncture produced noticeable yet non-significant improvement in sleep-onset latency times. Between-group differences in other sleep related variables were not statistically significant.
Conclusion

Our data suggest that true acupuncture may improve certain aspects of sleep, including sleep efficiency and possibly sleep-onset latency, in multiple myeloma patients undergoing HSCT. By studying patient reported outcomes in future larger scale studies, acupuncture’s role in improving sleep quality during HSCT treatment can be further elucidated.
Low-Dose Statins Improve Prognosis of Patients with Ischaemic Stroke Undergoing Intra-Arterial Thrombectomy: A Prospective Cohort Study
Authors: Cui Chaohua , Dong Shuju , Liu Qian , Bao Jiajia , Gao Lijie , Li Yanbo , He Li 
Published: December 2021

Abstract
Background: High-dose statins are recommended as preventive drugs in guidelines for patients with ischaemic stroke undergoing thrombectomy. Not only in clinical practice but also based on large-scale studies, low-dose statins have been widely used and demonstrated to be efficient in Asian populations. However, it remains unknown whether low-dose statin is related to the prognosis of patients with thrombectomy. Can low-dose statins reduce the risk of bleeding at the same time?Methods: We prospectively collected data from patients with acute ischaemic stroke undergoing intra-arterial thrombectomy. Efficacy outcomes were National Institutes of Health Stroke Scale (NIHSS) score improvement at 7 days after admission and a favourable functional outcome (FFO) at 90 days. Safety outcomes were rates of in-hospital haemorrhage events and death within 2 years. Results: We included 256 patients in this study. Compared with the control group, the low-dose statin group had a higher NIHSS improvement rate at 7 days, a higher FFO rate at 90 days and a lower death rate within 2 years. The low-dose statin group had a lower percentage of gastrointestinal haemorrhage. Statin use was significantly related to an improved NIHSS score (p=0.028, OR=1.773) at 7 days and FFO (P<0.001, OR=2.962) at 90 days and to lower death rates (P=0.025, or=0.554) within 2 years.Conclusion: In Asian acute ischaemic stroke patients with intra-arterial thrombectomy, low-dose statin use was significantly related to NIHSS improvement at 7 days, FFO at 90 days and decreased death rates within 2 years.
A Qualitative Study on the Feasibility and Acceptability of Establishing Health Technology Assessment (HTA) in a Low Income Country Setting: The Case of Malawi
Authors: Mfutso-Bengo Joseph , Jeremiah Faless , Kasende-Chinguwo Florence , Ng’ambi Wingston , Nkungula Nthanda , Kazanga-Chiumia Isabel , Juma-Kunyenga Mercy , Chawani Marlen , Chinkhumba Jobiba , Twea Pakwanja , Manthalu Gerald , Nkhoma Dominic , Colbourn Tim , Revill Paul , Sculpher Mark 
Published: December 2021

Abstract
BackgroundThe objective of this study was to assess the feasibility and acceptability of institutionalizing Health Technology Assessment (HTA) in Malawi focusing on the form, scope, capacity and financing requirements for a limited resource setting such as Malawi.MethodsThis study employed a desk review and qualitative research methods. An extensive literature review was conducted on relevant key policy documents, reports and publications to understand the status of HTA in Malawi. The study included one focus group discussion with 7 participants and 12 key informant interviews with key stakeholders selected purposely based on their knowledge and expertise in HTA. ResultsThe study found that partial or informal HTA processes exist and that HTA is practiced without a standardized framework. The partial HTA processes are executed through three structures; Ministry of Health Senior Management Team, Technical Working Groups and Pharmacy and Medicines Regulatory Authority (PMRA) with varying levels of effectiveness. The results revealed that lack of an institutional HTA creates severe shortfalls. This includes partial HTA mechanisms, limited evidence use, especially concerning cost-effectiveness, lack of a standardized framework for technology adoption, donor pressure, lack of resources for the HTA process and technology acquisition, laws and practices that undermine cost-effectiveness considerations. ConclusionInstitutionalizing HTA in Malawi is acceptable and feasible. The results suggest that any HTA institutionalization in the short to medium term could involve strengthening the capacity of PMRA to appraise Cost-effectiveness Analysis (CEAs) within academia and MOH health financing division. Furthermore, rather than creating new HTA institutions, country-specific assessments should precede any specific recommendations for new technology adoptions. A technical capacity in Academic institutions such as Health Economics and Policy Unit (HEPU) at Kamuzu University of Health Sciences (KuHes) can be developed either as “offshore” HTA capacity fully aligned to MOH and executing HTA evidence and knowledge management function in a sub-contractor capacity.Running HeadHealth technology assessment in Malawi
Empathy Alleviates the Learning Burnout of Medical College Students Through Enhancing Resilience
Authors: Wu Wenzhi , Ma Xiao , Liu Yilin , Qi Qiqi , Guo Zhichao , Li Shujun , Yu Lei , Long Qing , Chen Yatang , Teng Zhaowei , Zeng Yong 
Published: December 2021

Abstract
Objective The problem of learning burnout of medical students is becoming prominent, and empathy can play a good predictive role in learning burnout. The present study aimed to investigate the relationship between empathy and learning burnout, as well as the mediation effect of resilience in this relation. Methods A random sample of 588 college students from a key medical university in Yunnan Province was investigated using the Basic Empathy Scale, Learning Burnout Scale, and Connor-Davidson Resilience Scale. All the measures showed good reliability and validity in the present study. Data were analyzed using SPSS 23.0 and Amos 22.0. Results Using structural equation modeling, we tested a conceptual model indicated that: (1) medical students' empathy negatively and significantly predicted learning burnout; (2) medical students' empathy positively predicts mental resilience; (3) resilience of medical students negatively predicts learning burnout; (4) resilience partially mediated the relationship between empathy and learning burnout of medical students, while also controlling for family socioeconomic status.Conclusion These findings highlight the mediating role of resilience in the effect of empathy on learning burnout of medical college students. It may contribute to a better understanding of the effect of empathy. Moreover, it can also provide constructive suggestions for protecting and improve empathy and resilience of medical college students.
Temporal and Spatial Water Quality Assessment for Rivers in Metropolitan Areas Using Multivariate Statistics and Water Quality Indices: A Case Study of the Geumho River, Korea
Authors: Jo Chang Dae , Kim Jung Min , Kim Seong Min , Kwon Heon Gak 
Published: December 2021

Abstract
The Geumho River in South Korea passes through a metropolitan area with a high population density and multiple industrial complexes and, therefore, the water quality of this river is of significance for human health and economic activities. This study aims to assess the water quality of the Geumho River to inform river water quality management and improve pollution control using multivariate statistics and the Korean Water Quality Index (KWQI). Principal component and factor analysis identified those factors related to organic pollutants and metabolism (principal factor 1), and phosphorus and fecal coliform content (principal factor 2). In a cluster analysis, time was considered by distinguishing between seasons (spring, summer, autumn, and winter) and space was considered based on upstream (US), midstream (MS), and downstream (DS) river sections. Seven temporal variables and six spatial variables were extracted from the discriminant analysis (DA) results; the most important water quality variables were high during the spring and summer seasons and in the MS and DS regions. Temporally, the KWQI was highest in winter (70.9) and lowest in spring (59.2), whereas spatially, KWQI values were highest in the US (67.5) and lowest in the MS (56.4) sections. These results indicate that to be most effective, water management interventions in the Geumho River should focus on the urban midstream section and spring seasons.
Chronic Pain And Depressive Symptoms In Chinese Middle-Aged And Older Adults:A Follow Up Study
Authors: Liu Jialin , Chen Zixuan , Yu Yuke , Wang Qin , Liu Xiuxiu , Yuan Ping 
Published: December 2021

Abstract
Objective: This study aimed to analyze the effects of chronic pain on the occurrence of depressive symptoms in Chinese middle-aged and older adults, and to provide a scientific basis for reducing the incidence of depressive symptoms, improving the quality of life in middle-aged and older adults, and reducing the disease burden in the aging population.Methods: a prospective study was conducted to select adults aged 45 years or older from the longitudinal study of China Health and elderly care follow-up survey (Charls) (2015 and 2018). Pain was assessed according to the patient's self exposure, and depression was assessed using the Chinese version of the center for epidemiological research Depression Scale (CES-D). Univariate analysis and binary logistic regression model were used for analysis. Results: The 3-year cumulative incidence of depression in chronic pain patients was 52.4% and the annual incidence was 17.5% in the middle-aged and elderly Chinese population. Univariate analysis showed statistically significant differences in the incidence of depressive symptoms between the different genders, age, residence, education level, marriage, self perceived health status, nocturnal sleep time, number of social activities in the past month, smoking, alcohol consumption, impaired ADL and Medicare insurance coverage. This study, after controlling for demographic characteristics, health status and health behaviors, Different pain conditions remained statistically significant for depression in middle-aged and older adults. Compared with middle-aged and older adults without pain, both Unisomatic pain (OR = 1.388) and Multiple somatic pain (OR= 1.869) increased the risk of depression in the middle-aged and older populations. Conclusion: chronic pain is associated with the risk of depressive symptoms in middle-aged and elderly people, and the incidence of depression in middle-aged and elderly people in China is not optimistic.
Synthesis of Highly Active Si-doped TiO2 Nanotube/SnS Hybrids for Photocatalytic Degradation of Toxic Dyes
Authors: Ma Ning , He Hai-Yan 
Published: December 2021

Abstract
Heterostructures with nanoscale sizes have great superiorities in photocatalytic environment decontaminant because of their efficient interface charge transfer and great surface area. This work reports the facile fabrication of nano-tubular TiO2 and Si-doped TiO2 (NTs) hybridizing SnS nanocrystallites and their high-efficient photocatalytic activity. The fabricated nanostructures show wide light absorption in the UV-visible region. The SBET, light absorption, hydrophilicity, and photo-induced super hydrophilicity were enhanced by Si-doping and SnS modification. Moreover, high-efficient interface charge transfer was produced after the SnS modification and further enhanced by the Si doping because of band structure modulation. Thus, the Si-doped TiO2 nanotubes/SnS heterostructures showed a remarkably enhanced photocatalytic and Fenton-like photocatalytic activities in dye wastewater treatment than the TiO2 NTs. This work suggests potential materials and their facile fabrication process for the photocatalytic application of environmental decontamination.
The Influence of the Oxygen Vacancies on the Pt/TiO2 Single-atom Catalyst – a DFT Study
Authors: Zhang Yongkang , Wang Yuhang , Su Kaibin , Wang Fengping 
Published: December 2021

Abstract
The titanium dioxide (TiO2) surface is suitable as a substrate for single-atom catalysts(SACs). As a common defect on TiO2, oxygen vacancies may have a significant impact on the adsorption and activity of the adatoms. This work aims to investigate whether titanium dioxide containing surface oxygen vacancies is more suitable as a base material for SACs. This paper calculates the changes in the adsorption energy of Pt atom and the energy of the d-band center on the perfect surface and the surface containing oxygen vacancies. Concerning the perfect surface, the surface containing oxygen vacancies fixes the Pt atom more firmly, and increases the center energy of the d-band of Pt, thereby improving the performance of Pt atom as SACs. Consequently, the (110) surface of Rutile TiO2 with oxygen vacancies may be the best substrate for SACs.
Effects of Aerobic, Resistance and Combined Training on Endothelial Function and Arterial Stiffness in Older Adults: Study Protocol for a Systematic Review and Meta-Analysis
Authors: Silva Raphael Silveira Nunes da , Silva Diego , Waclawovsky Gustavo , Schaun Maximiliano Isoppo 
Published: December 2021

Abstract
Introduction: Aging is an independent risk factor for cardiovascular events. It promotes vascular dysfunction which is associated with risk factors for cardiovascular diseases (CVDs). Exercise can modulate vascular function parameters, but little is known about the effects of different modalities of training (aerobic, resistance and combined) on endothelial function and arterial stiffness in older adults. Methods: This systematic review study will include randomized controlled trials (RCTs) selected from the electronic databases MEDLINE (PubMed), Cochrane, LILACS, EMBASE and Web of Science. We will follow the PRISMA guidelines and PICOS framework. Studies involving both male and female older adults (≥60 years old) with or without comorbidities undergoing aerobic, resistance and/or combined training compared to a control group (no exercise) will be eligible. We will use Cochrane Risk of Bias 2 (RoB 2) tool to evaluate the quality of individual studies and GRADE to assess the strength of evidence. Statistical analyses will be conducted with RStudio for Windows (v1.3.959) using R package meta. Discussion: A systematic review and meta-analysis involving data from studies of older adults would deepen our understanding of vascular adaptations to exercise training in this population. It could provide new insights into how health providers can improve patient management and prevention of cardiovascular events in older adults. Systematic Review Registry: The study protocol for this review is awaiting approval for registration in the International Prospective Register of Systematic Reviews (PROSPERO) (ID 42021275451).