bluuebunny/crossref_metadata_2025_split huggingface dataset:
The institutionalisation of sustainability reporting in management practice: evidence through action research
Authors: Tarquinio Lara , Xhindole Chiara 
Published: November 2021

PurposeThis paper aims to explore why a company voluntarily engages in the sustainability reporting process, how this process becomes institutionalised and the resulting effects.Design/methodology/approachThe research focusses on a single case study, conducted following an action research approach and interpreted through the lens of institutional work. According to the institutional work theoretical perspective, the individual or organisation is responsible for creating, maintaining or disrupting institutions.FindingsThe case company, Deco S.p.A., undertook sustainability reporting to clarify the values that the company was founded upon and how those values translate into management practice. By institutionalising the sustainability reporting process, Deco S.p.A. found its corporate climate improved, various aspects of its operations could be rationalised and the information gathered to produce the report was valuable for decision support.Practical implicationsThis research project contributes to understanding why and how a company institutionalises its sustainability reporting. It also provides a better understanding of the internal forces that drive the voluntary reporting of sustainability issues and sheds light on the stages of the institutionalisation process.Social implicationsThe authors find that universities have a role to play in promoting the sustainability of companies, as they can transform the knowledge produced from research into useful knowledge for managing and reporting sustainability issues.Originality/valueThis four-year action research project contributes to the literature on both engagement research and the institutionalisation of sustainability reporting practices. The authors also expose some of the drivers affecting a company’s approach to sustainability reporting.
Mute Force and Ignorance: Incivility and Gender in Scotland
Authors: Higgins Michael , Smith Angela 
Published: November 2021

AbstractThis article considers the complex relationship between civility and gender in Scottish politics. It addresses two themes that have dominated discussion of Scotland's political tone. The first has been the seeming rise in intemperate political discourse, amplified by social media and the divisiveness of Scottish independence. The second has been those developments in the representation of gender in Scottish politics, both in the composition of the Scottish Parliament and in discourses around First Minister, Nicola Sturgeon. We also focus in on discourses surrounding a recent breach of civility by male Liberal Democrat MSP, Alex Cole‐Hamilton, in which Cole‐Hamilton is recorded mouthing an expletive towards a female Scottish government minister during a Zoom meeting of the Scottish Parliament's Equalities and Human Rights Committee on 11 February 2021. Analysis of this includes political responses to the ‘outburst’ and its subsequent media coverage, and examines, in particular, associations with masculinity and the relevance of the mitigating pleas of exasperated spontaneity. The article makes broader associations between the representation of this example of political incivility and those asymmetrical gender power relations given prominence by the #MeToo movement. Drawing on literature about angry populism, the article draws lessons about how mainstream politicians weaponise the language of incivility.
Hospital management practices and medical device costs
Authors: Grennan Matthew , Kim Gi Heung , McConnell K. John , Swanson Ashley 
Published: November 2021

AbstractObjectiveTo determine whether the variation in prices paid for cardiac medical devices was associated with management practices in cardiac units.Study settingCardiac units in US hospitals.Study designWe regressed unit prices on management practice scores and other hospital characteristics, with and without controls for device fixed effects, for the 11 top‐spending cardiac device categories.Data collectionA trusted third party that had entered into a confidentiality agreement combined de‐identified medical device price data for N = 213 US hospitals from ECRI's Supply Guide benchmarking service, with survey responses regarding management practices in those hospitals' cardiac units; the resulting merged data were made available to researchers for analysis with hospital identifiers removed. N = 1980 hospitals with interventional cardiac catheterization laboratories and at least 25 annual acute myocardial infarction discharges in 2010 were eligible for inclusion; N = 648 responded to the management practices survey; N = 213 subscribed to Supply Guide and purchased at least one of 11 top cardiac medical device categories.Principal findingsCardiac units with better management practices paid lower prices for cardiac devices (percent decrease in price for one standard deviation increase in management score = 1.33%, 95% confidence interval 0.99–1.67). This was comparable in magnitude to the price decrease associated with a one standard deviation increase in patient volume.ConclusionsBetter management practices were associated with lower device prices. This relationship is robust, but modest in magnitude. This modest magnitude is similar, though, to other events expected to lower input prices, such as transparency in the form of benchmarking information and hospital mergers.
The use of fly artifacts in a crime scene: Is there any application for forensic toxicology?
Authors: Giorgetti Arianna , Pelletti Guido , Fais Paolo , Giovannini Elena , Barone Rossella , Pelotti Susi , Pascali Jennifer P. 
Published: November 2021

AbstractFly artifacts (FA) are bloodstains resulting from insect activity at a crime scene, usually by feeding on human blood. Whether these artifactual stains might be useful for forensic toxicological investigations in cases of absence of conventional and unconventional matrices, for example, in cases concealment of the body or of extensive putrefaction, has not yet been investigated. The purpose of this study is to understand if FA trace evidence permits toxicological analysis when traditional matrices are not available. To this aim, FA experimentally produced by Calliphora vomitoria feeding on human blood of a cocaine and heroin user were collected from absorptive and non‐absorptive material. FA material was analyzed by a new simple and fast LC‐MS/MS method. Results were evaluated in terms of presence of the drug and relative amount of the detected molecules. From a qualitative point of view, the analysis of FA revealed all the substances originally detected in post‐mortem blood in both cases. The ratios of cocaine/benzoylecgonine, codeine/morphine, and 6‐monoacetylmorphine/morphine recovered in FA from cotton‐textile materials and from non‐absorptive surfaces were consistent with data resulted from original post‐mortem blood. The preliminary study herein reported demonstrated that FA are extremely informative in case of cocaine and heroin users and merit further research in order to be applied in real caseworks.
cAMP: A second messenger involved in the mechanism of midgut alkalinization in Lutzomyia longipalpis
Authors: Nepomuceno Denise Barguil , D’Ávila Pessoa Grasielle Caldas , Koerich Leonardo Barbosa , Pereira Marcos Horácio , Sant'Anna Mauricio Roberto Viana , Araújo Ricardo Nascimento , Gontijo Nelder Figueiredo 
Published: November 2021

AbstractThe sand fly Lutzomyia longipalpis is the main vector of Leishmania infantum in the Americas. Female sand flies ingest sugar‐rich solutions and blood, which are digested in the midgut. Digestion of nutrients is an essential function performed by digestive enzymes, which require appropriate physiological conditions. One of the main aspects that influence enzymatic activity is the gut pH, which must be tightly controlled. Considering second messengers are frequently involved in the coordination of tightly regulated physiological events, we investigated if the second messenger cAMP would participate in the process of alkalinization in the abdominal midgut of female L. longipalpis. In midguts containing the indicator dye bromothymol‐blue, cAMP stimulated the alkalinization of the midgut lumen. Through another technique based on the use of fluorescein as a pH indicator, we propose that cAMP is involved in the alkalinization of the midgut by activating HCO3– transport from the enterocyte's cytoplasm to the lumen. The results strongly suggested that the carrier responsible for this process would be a HCO3−/Cl− antiporter located in the enterocytes’ apical membrane. Hematophagy promotes the release of alkalinizing hormones in the hemolymph; however, when the enzyme adenylyl cyclase, responsible for cAMP production, was inhibited, we observed that the hemolymph from blood‐fed L. longipalpis’ females did not stimulate midgut alkalinization. This result indicated that hormone‐stimulated alkalinization is mediated by cAMP. In the present study, we provide evidences that cAMP has a key role in the control of intestinal pH.
Assessment of the di‐ and tri‐chlorinated haloacetic acids during broiler prechilling
Authors: Shao Liangting , Qin Yue , Xu Xinglian , Wang Huhu 
Published: November 2021

AbstractSodium hypochlorite (NaClO) has been widely used at 100 ppm concentration during poultry slaughter to reduce carcass microorganism loads. However, its use in poultry processing is restricted owing to the potential risks of disinfection by‐products (DBPs) that can be produced by the reaction of NaClO with poultry meat components. This study assessed whether dichloroacetic acid (DCAA) and trichloroacetic acid (TCAA), as primary DBP representatives, were produced when NaClO was used as a disinfectant in various methods during broiler prechilling. Headspace gas chromatography‐mass spectrometry for the quantitative determination of DCAA and TCAA in 180 prechilling water samples and 30 broiler meat samples, obtained from large standard slaughterhouses equipped with an online monitoring system to control the NaClO concentration between 50 and 100 ppm, showed that neither DCAA nor TCAA were detected. In simulation assays, haloacetic acids (HAAs) were not detected when the concentration of the NaClO solution was less than 200 ppm with low frequency addition; however, more than 0.1 mg/L of DCAA and TCAA were detected on applying 200, 300, 400, 500, and 1000 ppm NaClO at high frequency. These findings indicated that adding high concentrations of NaClO and frequently adding low levels pose a potential risk of DBP formation. This investigation provides a basis for the establishment of food risk and the scientific use of NaClO in poultry processing, and contributes to the evaluation of DBPs in poultry slaughter.Practical ApplicationThis study confirmed the occurrences of DCAA and TCAA during broiler chilling processing, indicating that formation of HAAs in simulation systems was correlated with NaClO levels and validated the absence of DCAA and TCAA with less than 200 ppm, providing a basic study for food safety standards and regulations on the disinfectants used in food processing.
The science of recovery capital: where do we go from here?
Authors: Best David , Hennessy Emily A. 
Published: November 2021

AbstractBackgroundThe concept of recovery capital (RC) has emerged in studies and discussions of the addiction recovery process and as a potential metric and marker for recovery gains. Although conceptual and applied development of the concept in the 20 years since the term was coined has increased, there remains insufficient clarity of key domains, factors and best practice research and applications for populations experiencing addiction. We aimed to review progress around the conceptualisation and operationalisation of RC and to consider future directions for a science of recovery capital.MethodWe provided a brief overview of theoretical foundations and advances, empirical measurement and application in treatment and continuing care settings. We next introduced four primary areas for addiction science to address, namely: (i) conceptual development (e.g. how RC domains are unique, but interrelated entities, valence of RC), (ii) empirical testing, adequacy of measurement and analysis, (iii) directions for novel application in treatment and recovery settings and (iv) dissemination and communication to policy, practice and lived experience groups. In this review, we also focussed on some of the challenges that must be addressed for a science of RC, which could produce long‐term impact in treatment and policy.ResultsDespite burgeoning empirical work on RC, its application and translation has been unsystematic. The field currently relies on self‐report questionnaires for the development of the theory and quantification of RC. Therefore, there is an urgent need for rigorous and systematic conceptual and empirical development of RC.ConclusionsA formal collaboration between scholars, practitioners and experts by experience worldwide would move recovery capital forward in an empirically driven and culturally appropriate manner, as would testing its applicability at individual, organisational and societal levels.
Clinical features of patients with Yin Yang 1 deficiency causing Gabriele‐de Vries syndrome: A new case and review of the literature
Authors: Khamirani Hossein Jafari , Zoghi Sina , Namdar Zahra Mehdipour , Kamal Neda , Dianatpour Mehdi , Tabei Seyed Mohammad Bagher , Mohammadi Sanaz , Dehghanian Fatemeh , Farbod Zahra , Dastgheib Seyed Alireza 
Published: November 2021

AbstractBackground: Gabriele‐de Vries syndrome is a rare autosomal dominant genetic disease caused by de novo pathogenic variants in YY1. In this study, we report a 10‐year‐old boy with a de novo novel pathogenic variant in YY1, the first Iranian patient with Gabriele‐de Vries Syndrome.Methods: The novel de novo pathogenic variant detected in this study (NM_003403:c.690delA, p.Glu231Ilefs*25) was identified by whole‐exome sequencing and confirmed by Sanger sequencing.Results: The proband presented with delayed motor and speech development, ataxia, abnormal gait, autistic behavior, brain atrophy, and severe learning disability. Finally, we provide a case‐based review of the clinical features associated with Gabriele‐de Vries Syndrome. Thus far, merely 13 Gabriele‐de Vries Syndrome patients have been reported in the literature.Conclusion: The investigations for a suspected case of Gabriele‐de Vries Syndrome must involve molecular diagnosis of the disease and its underlying genetic defect because the clinical investigations are generally variable and nonspecific.
Reclaiming Socialist Space, Caricaturing Socialism? Urban Interventions and the Cleansing of Political Content in State‐Socialist Public Housing After 2008
Authors: Krivy Maros 
Published: November 2021

AbstractThis article introduces the concept of retro‐utopian urbanism to analyse post‐2008 urban interventions in three state‐socialist public housing neighbourhoods in Eastern Europe. Through a comparative study of Petržalka (Bratislava, Slovakia), Lasnamäe (Tallinn, Estonia) and Bródno (Warsaw, Poland), I examine different approaches to combating the stigma associated with socialist housing. It is shown that these urban interventions are a double‐edged sword, in that they challenge the widespread notion that socialist urbanism is totalitarian by weakening the significance of socialist ideas. The article argues that urban interventions contribute to foreclosing socialist alternatives in the present when they normalise “postsocialism”, a term I use to refer to neoliberal capitalism’s ideological framework that sees socialism as obsolete. The concept of retro‐utopian urbanism provides a lens through which to reflect on the limitations and challenges of urban interventionism, and to rethink the debate on, and the persistence of, postsocialism in and beyond Eastern Europe.
Medication therapy of high‐dose methotrexate: An evidence‐based practice guideline of the Division of Therapeutic Drug Monitoring, Chinese Pharmacological Society
Authors: Song Zaiwei , Hu Yang , Liu Shuang , Wang Guanru , Zhai Suodi , Zhang Xianglin , Li Youping , Du Guanhua , Shi Yuankai , Chen Yaolong , Dong Mei , Guo Ruichen , Guo Wei , Huang Hongbing , Huang Xiaojun , Jing Hongmei , Ke Xiaoyan , Li Guohui , Miao Liyan , Niu Xiaohui , Qiu Feng , Shen Jingnan , Tang Jingyan , Wang Tianyou , Wang Xiaoling , Wang Zhuo , Wu Jiuhong , Zhan Siyan , Zhang Bikui , Zhang Lingli , Zhang Yanhua , Zhang Wei , Zhao Limei , Zhao Libo , Zhen Jiancun , Zheng Huyong , Zhu Zhu , Jiang Dan , Huang Zhencheng , Tan Zhiyuan , Lin Qiaonan , Zhao Rongsheng 
Published: November 2021

AimsA lot of medication risks related to high‐dose methotrexate (HDMTX) therapy still remain to be identified and standardized. This study aims to establish an evidence‐based practice guideline for individualized medication of HDMTX.MethodsThe practice guideline was launched by the Division of Therapeutic Drug Monitoring, Chinese Pharmacological Society. The guideline was developed following the WHO handbook for guideline development and the methodology of evidence‐based medicine (EBM). The guideline was initially registered in the International Practice Guidelines Registry Platform (IPGRP‐2017CN021). Systematic reviews were conducted to synthesize available evidence. A multicentre cross‐sectional study was conducted using questionnaires to evaluate patients' perception and willingness concerning individualized medication of HDMTX. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was used to rate the quality of evidence and to grade the strength of recommendations.ResultsMultidisciplinary working groups were included in this guideline, including clinicians, pharmacists, methodologists, pharmacologists and pharmacoeconomic specialists. A total of 124 patients were involved to integrate patient values and preferences. Finally, the guideline presents 28 recommendations, regarding evaluation prior to administration (renal function, liver function, pleural effusion, comedications, genetic testing), pre‐treatment and routine dosing regimen, therapeutic drug monitoring (necessity, method, timing, target concentration), leucovorin rescue (initial timing, dosage regimen and optimization), and management of toxicities. Of these, 12 are strong recommendations.ConclusionsWe developed an evidence‐based practice guideline with respect to HDMTX medication using a rigorous and multidisciplinary approach. This guideline provides comprehensive and practical recommendations involving the whole process of HDMTX administration to health care providers.
Camera trapping reveals multispecies use of water‐filled tree holes by birds and mammals in a neotropical forest
Authors: Delgado‐Martínez Carlos M. , Cudney‐Valenzuela Sabine J. , Mendoza Eduardo 
Published: November 2021

AbstractUsing camera traps, we documented that 21 bird and 9 mammal species use water‐filled tree holes (dendrotelmata) in the seasonal tropical forest of the Calakmul Biosphere Reserve, in southern Mexico. These species visited dendrotelmata primarily for foraging and drinking. The overall use of dendrotelmata was equally frequent between dry and rainy seasons but drinking behavior increased among birds during the dry season.Abstract in Spanish is available with online material.
Identifying management opportunities to combat climate, land, and marine threats across less climate exposed coral reefs
Authors: Kuempel Caitlin D. , Tulloch Vivitskaia J. D. , Giffin Alyssa L. , Simmons B. Alexander , Hagger Valerie , Phua Carol , Hoegh‐Guldberg Ove 
Published: November 2021

AbstractConserving coral reefs is critical for maintaining marine biodiversity, protecting coastlines, and supporting livelihoods in many coastal communities. Climate change threatens coral reefs globally, but researchers have identified a portfolio of coral reefs (bioclimatic units [BCUs]) that are relatively less exposed to climate impacts and strongly connected to other coral reef systems. These reefs provide a proactive opportunity to secure a long‐term future for coral reefs under climate change. To help guide local management efforts, we quantified marine cumulative human impact (CHI) from climate, marine, and land pressures (2013 and from 2008 to 2013) in BCUs and across countries tasked with BCU management. Additionally, we created a management index based on common management measures and policies for each pressure source (climate, marine, and land) to identify a country's intent and commitment to effectively manage these pressures. Twenty‐two countries (79%) had increases in CHI from 2008 to 2013. Climate change pressures had the highest proportional contribution to CHI across all reefs and in all but one country (Singapore), but 18 BCUs (35%) and nine countries containing BCUs (32%) had relatively high land and marine impacts. There was a significant positive relationship between climate impact and the climate management index across countries (R2 = 0.43, p = 0.02), potentially signifying that countries with greater climate impacts are more committed to managing them. However, this trend was driven by climate management intent in Fiji and Bangladesh. Our results can be used to guide future fine‐scale analyses, national policies, and local management decisions, and our management indices reveal areas where management components can be improved. Cost‐effectively managing local pressures (e.g., fishing and nutrients) in BCUs is essential for building a climate‐ready future that benefits coral reefs and people.
What does it take to have a mutually beneficial research collaboration across countries?
Authors: Rayadin Yaya , Buřivalová Zuzana 
Published: November 2021

AbstractWe reflect on the challenges researchers face when working in multi‐national collaborations in conservation science, whereby the researchers' countries are unequal in terms of financial and institutional support or other factors that contribute to a power imbalance. Based on our personal experiences and challenges, we outline four key aspects of the research cycle that provide opportunities to build or strengthen more equitable research partnerships: defining the shared research agenda, obtaining funding, publication, and the connecting thread of effective communication. We give recommendations for both the visiting scientist and the local scientist hosting international collaborators, as well as for institutions involved in conservation science. We hope that our perspectives can help other conservation scientists achieve productive and mutually beneficial collaborations that can lead to positive conservation outcomes.
Cholangiocarcinoma: A diagnostic dilemma on cytology
Authors: Shamsuddin Fatima , Mallik Mrinmay Kumar , Hussein Sundus , Alali Ali A. , Kapila Kusum 
Published: November 2021

AbstractBackgroundCholangiocarcinoma is a relatively rare form of adenocarcinoma which may resemble adenocarcinoma of pancreatobiliary origin or adenocarcinomas from many other sites in the body. As a result, its diagnosis relies mainly on clinical history and morphology.CaseA 64‐year‐old male with cirrhosis and worsening liver failure underwent fine needle aspiration of a radiologically detected liver mass. Cytological material showed a monomorphic population of cells arranged singly and in clusters, reminiscent of a neuroendocrine tumour (NET). Cell block morphology added to the diagnostic dilemma by showing a delicate vasculature among the tumour cells. Immunohistochemistry on the cell block revealed that cells were positive for CK7 and CK19 and negative for synaptophysin and chromogranin, thereby pointing towards a pancreatobiliary origin for the tumour and excluding an NET.ConclusionIn the case of liver aspirates, even when encountering confusing morphological entities, it is imperative to keep in mind the possibility of a rare neoplasm such as cholangiocarcinoma. In the absence of core needle biopsy, cell block sections prepared from aspirated material can provide appreciable immunohistochemistry results to resolve the diagnostic dilemma.