bluuebunny/crossref_metadata_2025_split huggingface dataset:
Levels of glutathione-related antioxidants in some tissues of stressed Wistar rats
Authors: Nwogueze Bartholomew Chukwuebuka , Ojieh Anthony Emeka , Aloamaka Chukwuemeka Peter , Igweh John Chukwuka , Onyesom Innocent 
Published: December 2021

Objectives:
Oxidative stress (OS)-related pathologic conditions in the tissues of living organism have been linked to exposure to stressful events within the environment. This study examined the impact of different kinds of stress exposure on glutathione (GSH)-related antioxidants. The effect of stress was examined using comparative levels of GSH, glutathione-S-transferase (GST) and glutathione peroxidase (GPx) in female Wistar rats.

Materials and Methods:
One hundred and sixty-eight adult female Wistar rats with body weights ranging between 150 and 200 g, were used for the study. The animals were distributed into 28 groups of six animals each. The experimental animals were routinely exposed to three different stressors; restraint chamber test, mirror chamber test and intruder chamber test for a duration of 1, 3 or 5 h per day for 1, 2 and 3 weeks, respectively. All animals were allowed free access to food (rat chaws), with water ad libitum. Animals were euthanise through cervical dislocation after the experimental period and the different target tissues were carefully harvested and homogenised for antioxidant estimation following standard procedure. Data obtained were statistically analysed and values expressed as mean ± standard error of mean and P < 0.05 level was considered as statistically significant.

Results:
Findings from this study elucidated the fact that exposure to stress is capable of causing marked OS and reducing GSH-based antioxidant activities in Wistar rats. A decline in the GSH level and GPx activity as observed in the study is an indication of alterations of kidney and brain tissue cellular integrity by free radicals generated during exposure to the stressors, while the observed significant increase in GST activity level in the affected tissues indicates compromised rapid exhaustion of the cellular system.

Conclusion:
Hence, we conclude that stress of different nature, intensity and duration can alter the levels of GSH-related antioxidants, especially in the kidney, ovary and brain tissues of stressed Wistar rats. The GSH levels in liver tissues were observed not to have changed significantly despite the oxidative damage caused by the stressors.
Behavioural and molecular effects of alcohol in the stress model of zebrafish
Authors: Franco-Restrepo Juan Esteban , Vargas Rafael Antonio Vargas 
Published: December 2021

Objectives:
Stress and anxiety disorders are common health problems that have been related to an increase in the likelihood of developing addictions, which have individual and social consequences. Although socially acceptable, alcohol is a substance that can generate dependence and abuse. Alcohol misuse, its relationship with stress and its consequences have been studied; however, multiple limitations are placed on clinical research in humans. In this exploratory work, we analysed the behavioural and molecular effects of joint exposure to ethanol and an unpredictable stress protocol (USP) in adult zebrafish.

Materials and Methods:
Adult zebrafish behaviour was studied employing unpredictable stress and behavioural tests. The tests were performed in stressed and nonstressed animals with and without exposure to known concentrations of alcohol. To evaluate the behaviour, tracking techniques were used on video recordings and parameters such as distance travelled, swimming speed and place preference as well as aggression patterns with mirror proximity tests were measured. In the control and 0.75% alcohol group, the expression of candidate stress-related genes (slc6a4a, slc6a3, comta and bdnf3) was analysed by RT-qPCR.

Results:
The results showed that concentrations of 0.75% alcohol reduced the locomotor activity of the fish, which can be interpreted as an increase in the anxiolytic effect of alcohol under nonstress conditions. Expression of comta, bdnf3 and slc6a3 was reduced in the stress and stress plus 0.75% ethanol groups and expression of slc6a4a was increased in the stress plus 0.75% alcohol group.

Conclusion:
Our exploratory work contributes novel insights about the molecular and behavioural effects of the combination of unpredicted stress and alcohol misuse. The USP and ethanol exposure increase anxiety behaviour and reduce the expression of genes involved in brain homeostasis. Future study of other pharmacological compounds and additional genes will be helpful for a deeper understanding of the molecular mechanisms involved in the response to stress and alcohol use.
Two out of three of octogenarians benefitted from delayed resection of spinal meningiomas
Authors: Vasankari Ville , Haeren Roel Hubert Louis , Niemela Mika , Korja Miikka 
Published: December 2021

Background:
Can elderly patients with thoracic meningioma and severe paraparesis benefit from delayed surgery?

Case Description:
Two out of three octogenarians with severe preoperative paraparesis (all wheelchair-bound) were able to walk again following delayed (60–120 days from onset of deficit) surgical resection of thoracic spinal meningiomas.

Conclusion:
Two out of three octogenarians with thoracic meningiomas causing severe paraparesis benefitted from the delayed (i.e. from 60 to 289 days) surgical resection of their tumors.
Prinsip Pengenalan Morfem dalam Bahasa Inggris: Kajian Morfologi
Authors: Mahamu Suhila , Sofyan Agus Nero 
Published: December 2021

This research aims to classify and identify morphemes recognition in English. The method used in this study is qualitative descriptive method. In providing data, the researcher uses listening and note-taking technique. The data used in this study were retrieved from the book Top Grammar: A Guide to Write English. While the theory used is the theory of the principle of morpheme recognition. The results of this discussion can be classified into six principles of morpheme recognition namely (1) the form of indefinite pronouns, comparative and superlative degree and reflexive pronouns; (2) singular and plural forms; (3) the form of the past participle in regular {-d}/{-ed} and irregular {–n} forms; (4) singular and plural nouns, present and past verbs; (5) the form of homonyms and in principle; and (6), the form of free morpheme and bound morpheme. From the results of the classification, morpheme units can be identified based on word form, word class and also the meaning that appears.AbstrakPenelitian ini bertujuan untuk mengklasifikasi dan mengidentifikasi pengenalan morfem dalam bahasa Inggris. Metode yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif. Dalam tahapan penyediaan data, penulis menggunakan teknik simak dan catat. Data yang digunakan dalam penelitian ini bersumber dari buku Top Grammar: A Guide to Write English. Teori yang digunakan adalah teori prinsip pengenalan morfem. Hasil dari pembahasan menunjukan bahwa terdapat enam prinsip pengenalan morfem, yaitu (1) terdapat pada bentuk indefinite pronoun, comparative dan superlative degree, serta reflexive pronoun; (2) terdapat pada bentuk tunggal dan jamak; (3) terdapat data pada bentuk past participle bentuk regular {-d}/ {-ed} dan irregular {–n}; (4) terdapat padakata benda tunggal dan jamak dan kata kerja present serta past; (5) terdapat pada bentuk homonim; (6) terdapat pada bentuk morfem bebas dan terikat. Dari hasil klasifikasi tersebut dapat disimpulkan bahwa satuan morfem dapat diidentifikasi berdasarkan bentuk kata, kelas kata, dan makna yang muncul.
Дослідження транспортного акустичного забруднення і факторів його залежності на прикладі перехресть магістральних вулиць міста Житомира
Authors: Бегерський Дмитро Богданович , Опанасюк Євгеній Григорович , Можаровський Микола Мар’янович , Вітюк Іван Васильович 
Published: December 2021

Шум від автомобільного транспорту – це найбільш розповсюджений вид несприятливого екологічного впливу на організм людини. Аналіз результатів відомих досліджень свідчить про те, що джерелами 60–80 % акустичного забруднення міст є рух транспортних засобів. Від шкідливого впливу автомобільного шуму страждають люди, які проживають або працюють поблизу магістральних вулиць. Він суттєво залежить від інтенсивності транспортного потоку, типів транспортних засобів, їх швидкості та технічного стану і значно зростає під час так званих годин «пік», коли рух транспортних засобів стає найбільш інтенсивним. Також рівень шуму може бути завищений внаслідок малої насиченості або повної відсутності зелених насаджень вздовж доріг, близькості від дороги будівель та їх зовнішнього покриття з низькою поглинаючою здатністю, відсутністю незабудованих зон та ін. Крім зазначених факторів, особлива увага в роботі приділена акустичному забрудненню територій, що безпосередньо прилягають до перехресть, оскільки там присутні додаткові фактори впливу на рівень шуму (збільшення концентрації транспортних засобів, додатковий шум при спрацюванні гальм, робота двигунів на перехідних режимах та ін.).
Play for Change: Primary School for Children with Impairments
Authors:   , Lim Joelle 
Published: December 2021

<p>Within the architecture of education, there is a lack of attention to the needs of children with disability. Globally, one in every ten children have a disability and there are approximately 90,000 aged 0-14 children living in households who have at least one disability in New Zealand. The cohort is one of the most marginalised and excluded group from the society, resulting in an inability to participate in classes leading to fewer opportunities to develop skills, experience and confidence. School designs are designed for children without disability, and many children with disabilities find that classrooms and outdoor environments are ill-suited for their health needs, resulting in low attendance rates, poor peer engagement and limited educational success. This thesis explores the role of architecture in facilitating the education of children with disabilities. Working from research-led design through to design-led research, it examines architecture as an educational tool. Examining classroom spaces, outdoor play and outdoor learning environment for children with disabilities, it questions the purpose of education. In addition, the research aims to desensitise the perceived architectural barriers within primary school that restricts participation for children with disabilities. The architectural design knowledge aims to improve design approaches for inclusivity in school, pedagogy and outdoor play environments. By addressing this issue, it could potentially create more positive and optimistic views and from the wider community, greater disability awareness.</p>
A Broadening of Prospects: Female Progression in Austen and Eliot
Authors:   , Verschaffelt Lydia 
Published: December 2021

<p>Austen and Eliot register the turbulence and transformation of their respective historic moments in the portrayal of a young heroine on the cusp of adulthood with a number of potential paths ahead of her. The heroines, like their societies, are caught between old and new as they seek to acknowledge the ties that bind them to the past and simultaneously create a future of their own. This dilemma reveals the nineteenth-century novel’s concerns of the individual’s ability to grow while being enmeshed in a network of relationships, and the place of the past in an increasingly unstable future. Beginning with Emma (1815) and The Mill on the Floss (1860), and concluding with a comparison of Persuasion (1817) and Middlemarch (1871), this thesis tracks Austen and Eliot’s depiction of female development which moves from a focus on the centrality of the childhood home, and in particular the heroine’s relationship with her father, to a narrative which ends on a more conscious note of ambiguity and broadening prospects. Emma and Mill both depict heroines who find their future in their past. Emma and Maggie develop and assert their own agency, but their circumstances and experiences of childhood bind them to their site of origin. Conversely, both Austen and Eliot’s later works enact a deliberate loosening of the hold the heroine’s childhood has on her, and Anne and Dorothea end up in very different places to where they began. They both reject their position as part of the rural landed gentry to instead gain entry into a more dynamic and inclusive community. This personal transition is accompanied by a more explicit delineation of the evolving socio-political landscape, an increase in the heroine’s mobility and fluidity, and an ending that frustrates a sense of stable closure in preference for one of more open possibility. Thus, so far from being read simply as ‘marriage plots’ Austen and Eliot subversively depict the young woman’s changing position and prospects as a matter of national importance.</p>
Assessing budgetary management of local government in Aceh, Indonesia
Authors:   , Farhana Intan 
Published: December 2021

<p>This interpretive case-based study explores issues of budgetary management in Aceh provincial government. Until 2018, Aceh showed significant problems in its budget cycle with the budget being approved late every year except 2014. Thus, this study aims to investigate the reasons for these delays, along with their impacts on budget execution. Further, as Aceh is a predominantly Muslim society with Islamic values and principles fundamental to its culture and identity, this study also explores whether Islamic teachings are well-embedded in its government budgeting. To investigate these issues, I gathered written materials related to the budgeting process and conducted 19 interviews with local government officials, politicians, Muslim scholars, and a corruption watchdog, analysing these through three linked accountability frameworks: considering accountability through relationship, responsibility, and answerability dimensions, Boltanski and Thévenot’s (1999) Sociology of Worth (SoW) framework, and Islamic accountability. I found the key reasons for the budget delays were miscommunications and heated debates in budget discussions between Aceh’s legislature and executive government resulting from conflicts of interest and priorities. The budget delays negatively affected budget execution, which, since Aceh’s economy depends heavily on government spending, reduced economic activity and so the social welfare of its people. Given the problems in its budgetary management, including budget delays, conflicting interests, and lack of transparency, the implementation of Islamic principles and values in Aceh’s government budgeting remains unsatisfactory. This study offers several contributions to the literature and practice: (i) it generates new ideas for the classification of SoW’s orders of worth when applied to public budgeting and accountability in a devout Muslim society; (ii) it outlines some challenges in implementing Islamic principles and values into government budgeting; and (iii) it notes some potential improvements for Aceh provincial government to achieve better budgetary management and accountability.</p>
Samoan identity through music composition: The agony of asking
Authors:   , Ah Sam Opeloge 
Published: December 2021

<p>In this thesis, Samoan music and identity are woven together and expressed simultaneously through new composition, critical reflection, and performance. This thesis explores creative practice in both Samoa and New Zealand, and it engages with critical insights in order to produce a body of new creative work in music. Through these efforts, this thesis contributes a new original understanding for how to articulate Samoan identity in current musical composition. In Samoa, cultural practices exist alongside global influences. These are found in song, language, contemporary music and dance in a variety of social contexts, and it is in this space of crossing boundaries where I explore my own identity as a Samoan-born, New Zealand composer, and a broader Samoan communal identity. The two contexts of my journey in Samoa and New Zealand offer sustained influences on my compositions both as a professional musician and educator. They provide very different expectations and cultures that I have negotiated, and have formed the basis of my creative work in this thesis. Adapting the Pasifika-centred framework of Epeli Hau’ofa in “Our Sea of Islands” (1993), in this thesis I provide a personal blueprint for a Samoan interpretation of creative practice in music, based on close readings and interpretations of concepts in new music composition. Through this work I deconstruct my own colonial past to rise above cultural stereotypes, and instead move towards finding connections with local-based styles and values of music. In doing so, my creative output offers an original voice as a composer that is firmly based in Samoan realities, just as it extends to experiences and with a diversity of musical practices. Through my creative work I offer unique musical spaces and mediums that expresses my Samoan identity, in both music and culture. In this way, new composition is a means of navigating and negotiating musical creativity. As I have discovered, I am not the only one moving in and out of these contexts as a Samoan musician and composer. I have worked together, alongside other Samoan composers such as Natalia Mann (based in Queensland, Australia), Metitilani Alo (based in Dunedin, New Zealand), Igelese Ete (based in Fiji) and Maori artists such as Riqi Harawira (based in Kaitaia, New Zealand) and artist BJ Natanahira (based in Kaitaia) sharing ideas and engaging in discussions around process of creativity and identity. In creating our own musical voices, we also take control of the forms and shapes used to express our identities musically and culturally. As Thomas Turino points out in Music as Social Life (2008) this is about navigating and negotiating our identity according to the spaces we move within, and the music we associate with through composition and performance. This is that journey.</p>
Epistemic Injustice
Authors:   , Simpson Hannah 
Published: December 2021

<p>“Epistemic injustice” is a fairly new concept in philosophy, which, loosely speaking, describes a kind of injustice that occurs at the intersection of structures of the social world and knowledge. While the concept was first put forward in the 1990’s, the most significant publication on the topic is Miranda Fricker’s book Epistemic Injustice: Power and the Ethics of Knowing, which was published in 2007. Since then, there has been something of an explosion of literature on the topic of epistemic injustice. However, the concept of epistemic injustice is one that is poorly understood. While Epistemic Injustice offers extensive analysis of some aspects of epistemic injustice, it does a poor job of explaining, overall, what epistemic injustice actually is, limiting most of that explanation to a small section in the introduction of the book. The way that epistemic injustice is presented in this section is highly ambiguous, with key terms being loosely defined (if at all), and the necessary and sufficient conditions of something being an epistemic injustice are left unclear. This remains unresolved in the literature beyond Fricker’s account: while there has been some progression in how we think about epistemic injustice beyond what Fricker’s work provides us with, there has been a general failure to adequately recognize and address the ambiguities of the Frickerian account of epistemic injustice. In this thesis, I aim to show that, despite superficial impressions to the contrary, the Frickerian account is fundamentally ambiguous and incomplete. Moreover, later attempts to address these issues by subsequent theorists have failed. This project, however, is not in vain. I conclude by proposing a new account of epistemic injustice that overcomes these problems with the Frickerian account, offering a way of understanding epistemic injustice that is both philosophically satisfying and practically useful.</p>
Supporting successful learning outcomes for secondary Pacific students through home-school relationships
Authors:   , Flavell Margaret 
Published: December 2021

<p>A need to improve learning outcomes for Pacific students has been highlighted by the Ministry of Education in Aotearoa/New Zealand, with the reflection that the education system has not adequately catered for these learners. The development of home-school relationships is recognised by the Ministry as one way of promoting the achievement of Pacific students; closer links with Pacific families are encouraged so that students’ needs may be better met. The aim of this research was to explore how secondary schools could develop relationships with Pacific families and communities in order to support students’ successful learning outcomes. A qualitative case study, using a grounded theory approach, was employed. An Appreciative Inquiry framework helped guide the research design to facilitate the exploration of how home-school relationships worked well within the context of a New Zealand town, and how they can be enhanced to benefit secondary Pacific learners. A Communities of Practice lens supported analysis; and an appreciation of Pacific relationality was supported by the theoretical frameworks, Teu le va and Talanoa Research Methodology (TRM). Key findings demonstrate the willingness and expertise from members of the Pacific community to support schools’ endeavours to cater for Pacific learners, helping address any barriers to family engagement. Despite the strong commitment from teachers and school leaders to work more closely and creatively with Pacific families, this study concludes that knowledge and ideas do not always flow freely between home and school. An inherent risk is that schools hold onto decision-making processes although there is a capacity within the Pacific community to offer effective solutions. To alleviate this risk, school structures need to open up to permit a freer exchange of information, prioritising relationships that accord with Pacific values. The bricolage of frameworks employed in this study have the potential to be applied to school settings for the review and development of home-school practices for Pacific families.</p>