bluuebunny/crossref_metadata_2025_split huggingface dataset:
An a priori error analysis of a porous strain gradient model
Authors: Baldonedo Jacobo , Fernández José R. , Magaña Antonio , Quintanilla Ramón 
Published: September 2021

AbstractIn this work, we consider, from the numerical point of view, a boundary‐initial value problem for non‐simple porous elastic materials. The mechanical problem is written as a coupled hyperbolic linear system in terms of the displacement and porosity fields. The resulting variational formulation is used to approximate the solution by the finite element method and the implicit Euler scheme. A discrete stability property and a priori error estimates are proved, from which the linear convergence of the numerical scheme is deduced under adequate regularity conditions. Finally, some numerical simulations are presented to show the accuracy of the finite element scheme studied previously, the evolution of the discrete energy and the behavior of the solution.
Revisiting the nature of the Pc pentaquarks
Authors: Du Meng-Lin , Baru Vadim , Guo Feng-Kun , Hanhart Christoph , Meißner Ulf-G. , Oller José A. , Wang Qian 
Published: September 2021

Abstract
The nature of the three narrow hidden-charm pentaquark Pc states, i.e., Pc(4312), Pc(4440) and Pc(4457), is under intense discussion since their discovery from the updated analysis of the process $$ {\Lambda}_b^0\to J/\psi {pK}^{-} $$

Λ
b
0

→
J
/
ψ

pK
−

by LHCb. In this work we extend our previous coupled-channel approach [Phys. Rev. Lett. 124, 072001 (2020)], in which the Pc states are treated as $$ {\Sigma}_c^{\left(\ast \right)}{\overline{D}}^{\left(\ast \right)} $$

Σ
c

∗

D
¯

∗

molecules, by including the $$ {\Lambda}_c{\overline{D}}^{\left(\ast \right)} $$

Λ
c

D
¯

∗

and ηcp as explicit inelastic channels in addition to the J/ψp, as required by unitarity and heavy quark spin symmetry (HQSS), respectively. Since inelastic parameters are very badly constrained by the current data, three calculation schemes are considered: (a) scheme I with pure contact interactions between the elastic, i.e., $$ {\Sigma}_c^{\left(\ast \right)}{\overline{D}}^{\left(\ast \right)} $$

Σ
c

∗

D
¯

∗

, and inelastic channels and without the $$ {\Lambda}_c{\overline{D}}^{\left(\ast \right)} $$

Λ
c

D
¯

∗

interactions, (b) scheme II, where the one-pion exchange (OPE) is added to scheme I, and (c) scheme III, where the $$ {\Lambda}_c{\overline{D}}^{\left(\ast \right)} $$

Λ
c

D
¯

∗

interactions are included in addition. It is shown that to obtain cutoff independent results, OPE in the multichannel system is to be supplemented with S-wave-to-D-wave mixing contact terms. As a result, in line with our previous analysis, we demonstrate that the experimental data for the J/ψp invariant mass distribution are consistent with the interpretation of the Pc(4312) and Pc(4440)/Pc(4457) as $$ {\Lambda}_c\overline{D} $$

Λ
c

D
¯

and $$ {\Sigma}_c{\overline{D}}^{\ast } $$

Σ
c

D
¯

∗

hadronic molecules, respectively, and that the data show clear evidence for a new narrow state, Pc(4380), identified as a $$ {\Sigma}_c^{\ast}\overline{D} $$

Σ
c
∗

D
¯

molecule, which should exist as a consequence of HQSS. While two statistically equally good solutions are found in scheme I, only one of these solutions with the quantum numbers of the Pc(4440) and Pc(4457) being JP = 3/2− and 1/2−, respectively, survives the requirement of regulator independence once the OPE is included. Moreover, we predict the line shapes in the elastic and inelastic channels and demonstrate that those related to the Pc(4440) and the Pc(4457) in the $$ {\Sigma}_c^{\left(\ast \right)}\overline{D} $$

Σ
c

∗

D
¯

and ηcp mass distributions from $$ {\Lambda}_b^0\to {\Sigma}_c^{\left(\ast \right)}\overline{D}{K}^{-} $$

Λ
b
0

→

Σ
c

∗

D
¯

K
−

and $$ {\Lambda}_b^0\to {\eta}_c{pK}^{-} $$

Λ
b
0

→

η
c

pK
−

will shed light on the quantum numbers of those states, once the data are available. We also investigate possible pentaquark signals in the $$ {\Lambda}_c{\overline{D}}^{\left(\ast \right)} $$

Λ
c

D
¯

∗

final states.
Impact of improved energy resolution on DUNE sensitivity to neutrino non-standard interactions
Authors: Chatterjee Sabya Sachi , Dev P.S. Bhupal , Machado Pedro A.N. 
Published: September 2021

Abstract
The full physics potential of the next-generation Deep Underground Neutrino Experiment (DUNE) is still being explored. In particular, there have been some recent studies on the possibility of improving DUNE’s neutrino energy reconstruction. The main motivation is that a better determination of the neutrino energy in an event-by-event basis will translate into an improved measurement of the Dirac C P phase and other neutrino oscillation parameters. To further motivate studies and improvements on the neutrino energy reconstruction, we evaluate the impact of energy resolution at DUNE on an illustrative new physics scenario, viz. non-standard interactions (NSI) of neutrinos with matter. We show that a better energy resolution in comparison to the ones given in the DUNE conceptual and technical design reports may significantly enhance the experimental sensitivity to NSI, particularly when degeneracies are present. While a better reconstruction of the first oscillation peak helps disentangling standard C P effects from those coming from NSIs, we find that the second oscillation peak also plays a nontrivial role in improving DUNE’s sensitivity.
Symbol alphabets from plabic graphs III: n = 9
Authors: Mago J. , Schreiber A. , Spradlin M. , Srikant A. Yelleshpur , Volovich A. 
Published: September 2021

Abstract
Symbol alphabets of n-particle amplitudes in $$ \mathcal{N} $$
N
= 4 super-Yang-Mills theory are known to contain certain cluster variables of G(4, n) as well as certain algebraic functions of cluster variables. In this paper we solve the C Z = 0 matrix equations associated to several cells of the totally non-negative Grassmannian, combining methods of arXiv:2012.15812 for rational letters and arXiv:2007.00646 for algebraic letters. We identify sets of parameterizations of the top cell of G+(5, 9) for which the solutions produce all of (and only) the cluster variable letters of the 2-loop nine-particle NMHV amplitude, and identify plabic graphs from which all of its algebraic letters originate.
Duality relations for overlaps of integrable boundary states in AdS/dCFT
Authors: Kristjansen Charlotte , Müller Dennis , Zarembo Konstantin 
Published: September 2021

Abstract
The encoding of all possible sets of Bethe equations for a spin chain with SU(N|M) symmetry into a QQ-system calls for an expression of spin chain overlaps entirely in terms of Q-functions. We take a significant step towards deriving such a universal formula in the case of overlaps between Bethe eigenstates and integrable boundary states, of relevance for AdS/dCFT, by determining the transformation properties of the overlaps under fermionic as well as bosonic dualities which allows us to move between any two descriptions of the spin chain encoded in the QQ-system. An important part of our analysis involves introducing a suitable regularization for singular Bethe root configurations.
Interpolating between multi-center microstate geometries
Authors: Shigemori Masaki 
Published: September 2021

Abstract
We study interpolation between two multi-center microstate geometries in 4d/5d that represent Lunin-Mathur geometries with circular profiles. The interpolating solution is a Lunin-Mathur geometry with a helical profile, and is represented by a 2-center solution with a codimension-2 source. The interpolating 2-center solution exhibits interesting features such as some of the charges being delocalized, and some of the charges getting transferred from the codimension-2 center to the other, codimension-3 center as the interpolation proceeds. We also discuss the spectral flow of this entire process and speculate on the relevance of such solutions to understanding general microstates of 3-charge black holes.
Mildly flavoring domain walls in Sp(N) SQCD
Authors: Benvenuti Sergio , Spezzati Paolo 
Published: September 2021

Abstract
We consider supersymmetric domain walls of four-dimensional $$ \mathcal{N} $$
N
= 1 Sp(N) SQCD with F = N + 1 and F = N + 2 flavors.First, we study numerically the differential equations defining the walls, classifying the solutions. When F = N + 2, in the special case of the parity-invariant walls, the naive analysis does not provide all the expected solutions. We show that an infinitesimal deformation of the differential equations sheds some light on this issue.Second, we discuss the 3d$$ \mathcal{N} $$
N
= 1 Chern-Simons-matter theories that should describe the effective dynamics on the walls. These proposals pass various tests, including dualities and matching of the vacua of the massive 3d theory with the 4d analysis. However, for F = N +2, the semiclassical analysis of the vacua is only partially successful, suggesting that yet-to-be-understood strong coupling phenomena are into play in our 3d$$ \mathcal{N} $$
N
= 1 gauge theories.
Cosmology of linear Higgs-sigma models with conformal invariance
Authors: Lee Hyun Min , Menkara Adriana G. 
Published: September 2021

Abstract
We consider general linear Higgs-sigma models as ultra-violet completions of the Higgs inflation. We introduce general higher curvature terms beyond Einstein gravity and recast them into a class of linear Higgs-sigma models in the scalar-dual formulation where conformal symmetry is manifest. Integrating out the sigma field in this class of linear sigma models, we obtain the same Higgs inflation Lagrangian of non-linear sigma model type in the effective theory. We show that the successful inflation for sigma field singles out the sigma-field potential derived from the R2 term and the tracker solution for dark energy at late times can be realized for the Rp+1 term with −1 < p < 0. We also discuss the implications of Higgs-sigma interactions for the inflation and the vacuum stability in the Standard Model.
Blow-up results for systems of nonlinear Schrödinger equations with quadratic interaction
Authors: Dinh Van Duong , Forcella Luigi 
Published: September 2021

AbstractWe establish blow-up results for systems of NLS equations with quadratic interaction in anisotropic spaces. We precisely show finite time blow-up or grow-up for cylindrical symmetric solutions. With our construction, we moreover prove some polynomial lower bounds on the kinetic energy of global solutions in the mass-critical case, which in turn implies grow-up along any diverging time sequence. Our analysis extends to general NLS systems with quadratic interactions, and it also provides improvements of known results in the radial case.
Rolle des Transplantationsbeauftragten
Authors: Sinner Barbara , Schweiger Stephan 
Published: September 2021

ZusammenfassungAlle Krankenhäuser, die nach dem Sozialgesetzbuch V als Entnahmekrankenhäuser definiert sind, sind verpflichtet, einen Transplantationsbeauftragten (TxB) zu stellen. Das Aufgabenfeld des TxB beinhaltet nicht nur die Spendererkennung, die Diagnose eines irreversiblen Hirnfunktionsausfalls sowie die Spenderevaluation und Organprotektion, sondern er begleitet den gesamten Organspendeprozess. Er verantwortet die Festlegung von innerklinischen Standards sowie die Organisation von Fort- und Weiterbildungen und ist Ansprechpartner rund um das Thema Organspende. Darüber hinaus fungiert er als Bindeglied zwischen der Koordinierungs- (Deutsche Stiftung Organtransplantation) und der Vermittlungsstelle (Eurotransplant). Seine Tätigkeit unterliegt dem Transplantationsgesetz und dessen Ausführungsgesetzen; er benötigt aber auch entsprechende Kenntnisse der verschiedenen Richtlinien zu Organspende bzw. -transplantation. Letztendlich ist der TxB auch für die Qualitätssicherung des Organspendeprozesses verantwortlich.
HIF2α regulates the synthesis and release of epinephrine in the adrenal medulla
Authors: Watts Deepika , Bechmann Nicole , Meneses Ana , Poutakidou Ioanna K. , Kaden Denise , Conrad Catleen , Krüger Anja , Stein Johanna , El-Armouche Ali , Chavakis Triantafyllos , Eisenhofer Graeme , Peitzsch Mirko , Wielockx Ben 
Published: September 2021

Abstract
The adrenal gland and its hormones regulate numerous fundamental biological processes; however, the impact of hypoxia signaling on adrenal function remains poorly understood. Here, we reveal that deficiency of HIF (hypoxia inducible factors) prolyl hydroxylase domain protein-2 (PHD2) in the adrenal medulla of mice results in HIF2α-mediated reduction in phenylethanolamine N-methyltransferase (PNMT) expression, and consequent reduction in epinephrine synthesis. Simultaneous loss of PHD2 in renal erythropoietin (EPO)-producing cells (REPCs) stimulated HIF2α-driven EPO overproduction, excessive RBC formation (erythrocytosis), and systemic hypoglycemia, which is necessary and sufficient to enhance exocytosis of epinephrine from the adrenal medulla. Based on these results, we propose that the PHD2-HIF2α axis in the adrenal medulla regulates the synthesis of epinephrine, whereas in REPCs, it indirectly induces the release of this hormone. Our findings are also highly relevant to the testing of small molecule PHD inhibitors in phase III clinical trials for patients with renal anemia.

Key messages

HIF2α and not HIF1α modulates PNMT during epinephrine synthesis in chromaffin cells.

The PHD2-HIF2α-EPO axis induces erythrocytosis and hypoglycemia.

Reduced systemic glucose facilitates exocytosis of epinephrine from adrenal gland.
Distressing psychotic-like experiences, cognitive functioning and early developmental markers in clinically referred young people aged 8–18 years
Authors: Barnes G. L. , Stewart C. , Browning S. , Bracegirdle K. , Laurens K. R. , Gin K. , Hirsch C. , Abbott C. , Onwumere J. , Banerjea P. , Kuipers E. , Jolley S. 
Published: September 2021

Abstract
Purpose
Neurocognitive difficulties and early childhood speech/motor delays are well documented amongst older adolescents and young adults considered at risk for psychosis-spectrum diagnoses. We aimed to test associations between unusual or psychotic-like experiences (PLEs), co-occurring distress/emotional symptoms, current cognitive functioning and developmental delays/difficulties in young people (aged 8–18 years) referred to Child and Adolescent Mental Health Services in South London, UK.

Methods
Study 1 examined receptive language, verbal learning and caregiver-reported speech and motor delays/difficulties in a sample of 101 clinically-referred children aged 8–14 years, comparing those reporting no PLEs (n = 19), PLEs without distress (n = 16), and PLEs with distress (n = 66). Study 2 tested associations of severity of distressing PLEs with vocabulary, perceptual reasoning, word reading and developmental delays/difficulties in a second sample of 122 adolescents aged 12–18 years with distressing PLEs.

Results
In Study 1, children with distressing PLEs had lower receptive language and delayed recall and higher rates of developmental delays/difficulties than the no-PLE and non-distressing PLE groups (F values: 2.3–2.8; p values: < 0.005). Receptive language (β = 0.24, p = 0.03) and delayed recall (β = − 0.17, p = 0.02) predicted PLE distress severity. In Study 2, the cognitive-developmental variables did not significantly predict PLE distress severity (β values = 0.01–0.22, p values: > 0.05).

Conclusion
Findings may be consistent with a cognitive-developmental model relating distressing PLEs in youth with difficulties in cognitive functioning. This highlights the potential utility of adjunctive cognitive strategies which target mechanisms associated with PLE distress. These could be included in cognitive-behavioural interventions offered prior to the development of an at-risk mental state in mental health, educational or public health settings.
A 2D qualitative movement assessment of a deceleration task detects football players with high knee joint loading
Authors: Di Paolo Stefano , Zaffagnini Stefano , Tosarelli Filippo , Aggio Fabrizio , Bragonzoni Laura , Grassi Alberto , Della Villa Francesco 
Published: September 2021

Abstract
Purpose
The deceleration (pressing) is a common situational pattern leading to anterior cruciate ligament (ACL) injury in football. Although mainly assessed for performance purposes, a stronger focus on movement quality might support the screening of at-risk athletes. The aim of the present study was to describe a 2D scoring system for the assessment of the deceleration task and to associate it with the knee joint loading (knee abduction moment) evaluated through the gold standard 3D motion capture. The hypothesis was that lower 2D scores would be associated with higher knee joint loading.

Methods
Thirty-four competitive football (soccer) players (age 22.8 ± 4.1, 16 females) performed a series of deceleration tasks. 3D motion analysis was recorded using ten stereophotogrammetric cameras, a force platform, and three high-speed cameras. The 2D qualitative assessment was performed via a scoring system based on the video analysis of frontal and lateral planes joint kinematics for five scoring criteria. The intra- and inter-rater reliabilities were calculated for each 2D scoring criteria. The peak knee abduction moment was extracted and grouped according to the results of the 2D evaluation.

Results
An ICC > 0.94 was found for all the 2D scoring criteria, both for intra-rater and inter-rater reliability. The players with low 2D frontal plane scores and low total scores (0–4) showed significantly higher peak knee abduction moment values (p < 0.001). A significant negative rank correlation was found between the total score and the peak knee abduction moment (ρ = − 0.25, p < 0.001).

Conclusions
The qualitative 2D scoring system described successfully discerned between athletes with high and low knee joint loading during a deceleration task. The application of this qualitative movement assessment based on a detailed and accurate scoring system is suitable to identify players and patients with high knee joint loading (high knee abduction moments) and target additional training in the scenario of the primary and secondary ACL injury risk reduction.

Level of evidence
Level IV.
AG codes from $${{\mathbb{F}}_{q^7}}$$-rational points of the GK maximal curve
Authors: Lia Stefano , Timpanella Marco 
Published: September 2021

AbstractIn Beelen and Montanucci (Finite Fields Appl 52:10–29, 2018) and Giulietti and Korchmáros (Math Ann 343:229–245, 2009), Weierstrass semigroups at points of the Giulietti–Korchmáros curve $${\mathcal {X}}$$
X
were investigated and the sets of minimal generators were determined for all points in $${\mathcal {X}}(\mathbb {F}_{q^2})$$

X
(

F

q
2

)

and $${\mathcal {X}}(\mathbb {F}_{q^6})\setminus {\mathcal {X}}( \mathbb {F}_{q^2})$$

X

(

F

q
6

)

\
X

(

F

q
2

)

. This paper completes their work by settling the remaining cases, that is, for points in $${\mathcal {X}}(\overline{\mathbb {F}}_{q}){\setminus }{\mathcal {X}}( \mathbb {F}_{q^6})$$

X

(

F
¯

q

)

\
X

(

F

q
6

)

. As an application to AG codes, we determine the dimensions and the lengths of duals of one-point codes from a point in $${\mathcal {X}}(\mathbb {F}_{q^7}){\setminus }{\mathcal {X}}( \mathbb {F}_{q})$$

X

(

F

q
7

)

\
X

(

F
q

)

and we give a bound on the Feng–Rao minimum distance $$d_{ORD}$$

d

ORD

. For $$q=3$$

q
=
3

we provide a table that also reports the exact values of $$d_{ORD}$$

d

ORD

. As a further application we construct quantum codes from $$\mathbb {F}_{q^7}$$

F

q
7

-rational points of the GK-curve.
Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages
Authors: Snijders Kirsten E. , Fehér Anita , Táncos Zsuzsanna , Bock István , Téglási Annamária , van den Berk Linda , Niemeijer Marije , Bouwman Peter , Le Dévédec Sylvia E. , Moné Martijn J. , Van Rossom Rob , Kumar Manoj , Wilmes Anja , Jennings Paul , Verfaillie Catherine M. , Kobolák Julianna , ter Braak Bas , Dinnyés András , van de Water Bob 
Published: September 2021

AbstractTagging of endogenous stress response genes can provide valuable in vitro models for chemical safety assessment. Here, we present the generation and application of a fluorescent human induced pluripotent stem cell (hiPSC) reporter line for Heme oxygenase-1 (HMOX1), which is considered a sensitive and reliable biomarker for the oxidative stress response. CRISPR/Cas9 technology was used to insert an enhanced green fluorescent protein (eGFP) at the C-terminal end of the endogenous HMOX1 gene. Individual clones were selected and extensively characterized to confirm precise editing and retained stem cell properties. Bardoxolone-methyl (CDDO-Me) induced oxidative stress caused similarly increased expression of both the wild-type and eGFP-tagged HMOX1 at the mRNA and protein level. Fluorescently tagged hiPSC-derived proximal tubule-like, hepatocyte-like, cardiomyocyte-like and neuron-like progenies were treated with CDDO-Me (5.62–1000 nM) or diethyl maleate (5.62–1000 µM) for 24 h and 72 h. Multi-lineage oxidative stress responses were assessed through transcriptomics analysis, and HMOX1-eGFP reporter expression was carefully monitored using live-cell confocal imaging. We found that eGFP intensity increased in a dose-dependent manner with dynamics varying amongst lineages and stressors. Point of departure modelling further captured the specific lineage sensitivities towards oxidative stress. We anticipate that the newly developed HMOX1 hiPSC reporter will become a valuable tool in understanding and quantifying critical target organ cell-specific oxidative stress responses induced by (newly developed) chemical entities.
Algebraic Geometry of Lie Bialgebras Defined by Solutions of the Classical Yang–Baxter Equation
Authors: Abedin Raschid , Burban Igor 
Published: September 2021

AbstractThis paper is devoted to algebro-geometric study of infinite dimensional Lie bialgebras, which arise from solutions of the classical Yang–Baxter equation. We regard trigonometric solutions of this equation as twists of the standard Lie bialgebra cobracket on an appropriate affine Lie algebra and work out the corresponding theory of Manin triples, putting it into an algebro-geometric context. As a consequence of this approach, we prove that any trigonometric solution of the classical Yang–Baxter equation arises from an appropriate algebro-geometric datum. The developed theory is illustrated by some concrete examples.
Effects of visual blur and contrast on spatial and temporal precision in manual interception
Authors: Schroeger Anna , Tolentino-Castro J. Walter , Raab Markus , Cañal-Bruland Rouwen 
Published: September 2021

AbstractThe visual system is said to be especially sensitive towards spatial but lesser so towards temporal information. To test this, in two experiments, we systematically reduced the acuity and contrast of a visual stimulus and examined the impact on spatial and temporal precision (and accuracy) in a manual interception task. In Experiment 1, we blurred a virtual, to-be-intercepted moving circle (ball). Participants were asked to indicate (i.e., finger tap) on a touchscreen where and when the virtual ball crossed a ground line. As a measure of spatial and temporal accuracy and precision, we analyzed the constant and variable errors, respectively. With increasing blur, the spatial and temporal variable error, as well as the spatial constant error increased, while the temporal constant error decreased. Because in the first experiment, blur was potentially confounded with contrast, in Experiment 2, we re-ran the experiment with one difference: instead of blur, we included five levels of contrast matched to the blur levels. We found no systematic effects of contrast. Our findings confirm that blurring vision decreases spatial precision and accuracy and that the effects were not mediated by concomitant changes in contrast. However, blurring vision also affected temporal precision and accuracy, thereby questioning the generalizability of the theoretical predictions to the applied interception task.