bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Age on Clinical and Radiological Outcomes of Hallux Valgus Surgery
Authors: Goh Graham S. , Tay Adriel You Wei , Thever Yogen , Koo Kevin 
Published: January 2021

Background: The prevalence of hallux valgus increases with age. However, no studies have compared the effectiveness of surgical correction among different age groups. This study investigated the influence of age on clinical and radiological outcomes following hallux valgus surgery. Methods: Patients who underwent correction for hallux valgus at an academic hospital were stratified into 3 age groups: younger (<50 years), middle-aged (50-59 years), and older (≥60 years). Functional outcomes and satisfaction questionnaires were collected preoperatively and at 6 months and 2 years postoperatively. Radiological recurrence and reoperations were recorded at follow-up. There were 193 patients (93% female): 34 younger, 74 middle-aged, and 85 older. Results: The preoperative hallux valgus angle was significantly greater in older patients ( P < .001). The older group had 3 perioperative complications ( P = .144) and showed a trend toward a longer hospital stay ( P = .083). There was no difference in visual analog scale, American Orthopaedic Foot & Ankle Society score, or SF-36 among the groups at 6 months or 2 years. Using multiple regression, age was not associated with any outcome score. The satisfaction rates were 82%, 78%, and 83% in the young, middle-aged, and older groups, respectively ( P = .698). There was no difference in the number of reoperations at a mean follow-up of 9.2 ± 2.2 years ( P = .778), and no patients underwent reoperation for recurrent hallux valgus. The risk of recurrence was 5 times higher in older patients compared with younger patients (OR, 5.15; 95% CI, 1.10-24.03; P = .037). Conclusion: Age did not influence the perioperative, functional, or subjective outcomes following hallux valgus surgery. However, older patients should be counseled on the higher risk of recurrence following surgical correction. Level of Evidence: Therapeutic, level III, retrospective comparative series.
Health education services utilization and its determinants among migrants: a cross-sectional study in urban-rural fringe areas of Beijing, China
Authors: Shao Shuang , Zhang Huirong , Chen Xiaolei , Xu Xiaojingyuan , Zhao Yali , Wang Meirong , Du Juan 
Published: January 2021

Abstract
Background
Domestic migration poses a challenge for China as migrants have little access to preventive healthcare services and are vulnerable to certain risks and diseases. This research sought to unveil and explore the determinant factors associated with health education utilization as a key aspect in basic public health services for migrants in Beijing, China.

Methods
A sample of 863 inter-provincial migrants, 18 years old and above, was selected by three-stage stratified cluster sampling method in urban-rural fringe areas of Beijing during 2016 to 2017. Face-to-face structured interviews were conducted in the questionnaire survey. The effects of the explanatory variables on health education utilization from predisposing, enabling, health behaviors and need variables were used to demonstrate by Anderson health service utilization model.

Results
The study revealed that 61.6% migrants desired to receive health education, while only 53.8% of them received in the past year. There were differences in the utilization and needs of health education among the migrants in different ages and genders. Many migrants desired to gain access to various types of health education information from the internet. Chi-square independence test lists such major determinant factors in migrants whole health education as age, “Hukou” registration system, marital status, education level, long-term residence plan in Beijing, one or more children in Beijing, employment status, housing source, average daily working time, exercises, health knowledge, smoking, self-rated health. The binary logistic regression indicates that the migrants with younger age, high education level, one or more children in Beijing, exercises and good self-rated health were more likely to receive whole health education. The results also show that average daily working time of enabling variables and exercise of health behavior variables were the strong and consistent determinants of three types of health education utilization, including communicable, non-communicable and occupational diseases.

Conclusion
Gaps exist between the needs and utilization in health education and more attention should be given to the migrants with heavy workload and low education level. Feasible policies and measures, such as multiple health information channels, should be vigorously implemented to ensure equitable and easy access to health education for migrants.
Massive intracranial hemorrhage caused by intraventricular meningioma: case report
Authors: Sumi Koichiro , Suma Takeshi , Yoshida Reona , Kajimoto Ryuta , Kobayashi Masato , Katsuhara Takamichi , Hirayama Koki , Tang Xiaoyan , Otani Naoki , Yoshino Atsuo 
Published: January 2021

AbstractBackgroundMeningiomas are the most common benign intracranial tumors, and commonly comprise high-vascularizing but slow-growing tumors. On the other hand, meningiomas arising from the ventricular system are of rare occurrence, and spontaneous hemorrhage is an infrequent event.Case presentationWe describe here the rare clinical manifestations of a 28-year-old female with acute intracranial hemorrhage located in the trigone of the lateral ventricle who was initially thought to have suffered an acute cerebrovascular accident, but was subsequently confirmed to have a benign intraventricular meningioma. To clarify the clinical features of such a rare course of meningioma, we also present a short literature review of acute intracranial hemorrhage caused by intraventricular meningioma.ConclusionsVentricular meningioma presenting with hemorrhage such as acute stroke is a rare event, but recognition of such a pathogenesis is important. Although further accumulation of clinical data is needed, we suggest that early surgery should be undertaken in patients with lateral ventricular meningioma, even if it is not so large or asymptomatic.
Suicidal attempt with caffeine overdose treated with dexmedetomidine: a case report
Authors: Kitano Teppei , Okajima Masaki , Sato Koji , Noda Toru , Taniguchi Takumi 
Published: January 2021

Abstract
Background
Caffeine is a widely used dietary stimulant, and cases of caffeine overdoses, sometimes leading to death, are increasing. We encountered a case of caffeine intoxication resolved with administration of the sedative agent dexmedetomidine.

Case presentation
We administered dexmedetomidine for sedation and to suppress sympathetic nerve stimulation in the case of an 18-year-old Japanese male who ingested a massive dose of caffeine with the intention of committing suicide. The patient was in an excited state and had hypertension, sinus tachycardia, and hypokalemia with prominent QT prolongation. After dexmedetomidine administration, the patient’s mental state, hemodynamics, and electrolyte levels were improved immediately. He was discharged without any sequelae 3 days later.

Conclusion
Cases of acute caffeine intoxication with agitation, sympathetic overactivity and adverse cardiac events would benefit with dexmedetomidine treatment.
Characterization of pharmacological properties of methanolic seed and stem bark extracts of Ziziphus mauritiana (BAU Kul) using in-vitro and in-vivo animal (Swiss albino male mice) model
Authors: Akanda Md. Khokon Miah , Hasan A. H. M. Nazmul 
Published: January 2021

Abstract
Background
Ziziphus mauritiana belongs to family of Rhamnaceae, is an improved fast-growing variety of plum and seasonal fruit which is very popular and commonly known as “BAU Kul” in Bangladesh. This study was designed to evaluate the medicinal values of seed and stem bark extracts of Ziziphus mauritiana.

Methods
Antioxidant, thrombolytic, membrane stabilizing, cytotoxic and antimicrobial activities were characterized using in-vitro methods and anti-diarrheal, analgesic and hypoglycemic activities were evaluated in Swiss albino male mice. The coarse powder of the plant parts were extracted with methanol and methanol portion of the extract was evaporated naturally under room temperature. Then the dried plant extracts were undergone for subsequent investigation.

Results
Total phenolic and flavonoid content, and antioxidant capacity of stem bark extract were higher than seed extract. Both extracts had similar DPPH (IC50 of seed 4.53 μg/ml and stem bark 4.13 μg/ml) and NO (IC50 of seed 5.92 μg/ml and stem bark 5.47 μg/ml) free radicals scavenging potential and seed extract was most cytotoxic (LC50 = 1.467 μg/ml). Stem bark extract showed higher thrombolytic and anti-inflammatory potential, and also exhibited 14 mm zone of inhibition against S. aureus. Stem bark extract showed highest anti-diarrheal (75.68% defecation inhibition, p˂ 0.001), analgesic (68.63%writhing inhibition, p˂0.001) and hypoglycemic activity (44.27% blood glucose reduction after 3 h, p˂0.001) at 400 mg/kg body weight dose.

Conclusion
This study confirms good medicinal properties of selected plant parts. Further studies on isolation and characterization of its bioactive compounds are highly required.
Evaluation of anti-arthritic and anti-inflammatory activities of Martynia annua L. Ethanolic extract
Authors: Kaushik Suruj , Jain Parag , Satapathy Trilochan , Purabiya Prerna , Roy Amit 
Published: January 2021

Abstract
Background
Arthritis is a disorder of change in joint architecture and ligament degeneration. Rheumatoid arthritis is an autoimmune disorder in which body’s immune system targets own cells and degrade them. Martynia annua L. has been used in Indian traditional therapies for the treatment of epilepsy, many types of inflammations, respiratory infection, sore throat and wound. The objective of the present study was to determine anti-inflammatory and anti-arthritic activities of M. annua ethanolic fruit extract.

Methods
The extraction was performed using ethanol as a solvent followed by phytochemical investigation of M. annua ethanolic fruit extract. Antioxidant and anti-hyaluronidase enzyme inhibition activities was performed for the fruit extract. In vivo anti-inflammatory of fruit extract was performed on Calotropis procera latex (CPL) induced paw edema in rats using ibuprofen as standard. Inflammation was observed at 0, 1, 2, 4 and 6 h. In vivo anti-arthritic of fruit extract was performed on Complete Freund’s adjuvant (CFA) induced arthritis in rats. Arthritis was observed at 0, 7, 14 and 21 day. X-Ray study was also performed for inflammatory and arthritic paw of rats.

Results
The qualitative phytochemical screening of fruit extract showed presence of flavonoids, terpenoids, saponins, tannins, steroids, glycosides, proteins, carbohydrates, amino acids and polysaccharides. The antioxidant activity of fruit extract was 49.1 as compared to standard 45.73 at 100 μl dose. The anti-hyaluronidase enzyme inhibition activity of fruit extract was 84.60 as compared to standard 94.21 at 100 μl dose.

Conclusion
It is evident from the study that Martynia annua L. extract possess both antioxidant and hyalurinodase inhibition activity at dose dependent manner as well as anti-arthritic and anti-inflammatory potential.
Instituciones, coaliciones callejeras e inestabilidad política: perspectivas teóricas sobre las crisis presidenciales
Authors: Pérez-Liñán Aníbal 
Published: January 2021

RESUMEN: En las últimas dos décadas, trece presidentes electos han sido removidos del cargo en América Latina. ¿Cómo debemos conceptualizar este nuevo patrón de inestabilidad política y cómo explicarlo? En la primera sección de este artículo se identifican una serie de categorías (renuncia anticipada, juicio político y golpe legislativo) que permiten delimitar con mayor claridad al fenómeno de interés. En la segunda sección se presentan dos perspectivas analíticas para entender el origen de estas crisis (una institucional y otra basada en los movimientos sociales) y se explora el papel de otras causas remotas, como los factores económicos. La sección tercera presenta varios problemas en la identificación de las causas de las crisis y presenta un modelo empírico que sugiere que la protesta popular y las condiciones institucionales interactúan para definir el resultado del proceso político. En las conclusiones se exploran las consecuencias de estas crisis para la democracia y el presidencialismo.ABSTRACT: In the past two decades, thirteen elected presidents have been ousted in Latin America. How should we conceptualize this emerging pattern of political instability and how can we explain it? The first section of the paper identifies some categories (early resignation, impeachment, and legislative coup) that help us delimit the phenomenon of interest. The second section reviews two analytical perspectives that seek to explain the origins of recent crises (one emphasizing institutions and the other one based on social movements) and discusses the relevance of more remote explanations such as economic conditions. The third section introduces some of the problems confronted by those trying to identify causes of political crises and presents an empirical model suggesting that popular protest and institutional conditions interact to determine the outcome of political processes. The conclusions explore the consequences of recent crises for democracy and presidentialism in the region.
Las preferencias ideológicas y políticas judiciales: un modelo actitudinal sobre el voto en el tribunal constitucional de ecuador
Authors: Basabe Serrano Santiago 
Published: January 2021

RESUMEN: El estudio del comportamiento, dinámicas e interacciones de los jueces es un campo de la Ciencia Política que, a pesar de su fertilidad, ha sido analizado residualmente en América Latina. Frente a ello, este trabajo propone un modelo formal sobre el comportamiento de los vocales del Tribunal Constitucional de Ecuador (TC) a través del que se argumenta que las preferencias políticas de los jueces influyen en la dirección que asumen sus votos. Analizado en un amplio período de actividades del TC (1999-2003), y recurriendo a una base de datos de 441 observaciones, el modelo de regresión lineal produce resultados que verifican empíricamente la hipótesis propuesta. Recurriendo a una metodología múltiple, en la que destaca la construcción de un indicador independiente para medir la ubicación ideológica de los jueces, el trabajo concluye sugiriendo criterios a partir de los que se abona el terreno para la posterior exploración, no sólo del voto judicial sino también de las lógicas que conducen los procesos de toma de decisiones en cortes y tribunales de justicia.ABSTRACT: The study of the behavior, dynamic and interactions of the judges, is a field of the Political Science that, in spite of its fertility, has been analyzed residually in Latin America. As opposed to it, this work proposes an formal model of the behavior of the judges of the Constitutional Court of Ecuador (TC) in which is argued that the political preferences of the judges influence in the direction who assume their votes. Tested in an ample period of activities of the TC (1999-2003), and resorting to a data base of 441 observations, the model of linear regression produces results that verify the propose explanatory hypothesis empirically. Resorting to a multiple methodology, in which it emphasizes the construction of an independent indicator to measure the ideological location of the judges, the work also concludes suggesting criteria from whom the land for the later exploration is paid, not only of the judicial vote but of the logics that the processes of decision making in courts of justice lead.
FLAVONOIDS AND PHENILPROPANOIDS OF THE ABOVE GROUND ORGANS OF THE BUPLEURUM MUL-TINERVE DC. OF THE FLORA OF THE BAIKAL REGION
Authors: Mirovich Vera Mikhaylovna , Olennikov Daniil Nikolayevich , Petukhova Svetlana Andreyevna , Posokhina Alina Alekseevna 
Published: January 2021

A study of the flavonoids and phenylpropanoids of the aerial organs of Bupleurum multinerve was carried out. Samples of raw materials were collected in the Baikal region in the vicinity of. Verkholensk, Irkutsk region. The raw materials were collected during the flowering period in 2019 in the herb-grass association. For analysis, raw materials were extracted with 70% ethyl alcohol in an ultrasonic bath for 30 minutes, followed by centrifugation of the extract. Compounds were identified by the UPLC-DAD-ESI-MS method in comparison with standard samples. In the aerial organs of B. multinerve, 15 compounds were identified (8 flavonoids and 7 phenylpropanoids). Flavonoids B. multinerve are derivatives of quercetin, kempferol, isoramnetin; phenylpropanoids – esters of quinic acid with coffee, ferulic, coumaric. The contents of B. multinerve compounds were first established: quercetin-3-O-glucuronide, kempferol-3-O-glucoside (astragaline), 5-O-p-coumaroylquinic acid, 5-O-feruloylquinic acid, 3-O-feruloylquinic acid, 3,5-di-O-caffeoylquinic acid; 4,5-di-O-caffeoylquinic acid. The quantitative content of glycosides of flavonoids isoramnetin-3-O-rutinoside (narcissin) 20.74 mg/g, quercetin-3-O-rutinoside (rutin) 19.53 mg/g, quercetin-3 was determined by MK-HPLC-UV in the aerial organs of B. multinerve -O-glucoside (isocvercitrin) 2.24 mg/g, camperol-3-O-glucoside (astragaline) 0.39 mg/g, quercetin-3-O-glucuronide 0.25 mg/g; quercetin flavonoid aglycones 0.43 mg/g; isoramnetin 0.53 mg/g; the predominant phenylpropanoids were 5-O-caffeoylquinic acid 6.60 mg/g, 3,5-di-O-caffeylquinic acid 1.58 mg/g. The total content of identified flavonoids was 44.97 mg/g, phenylpropanoids 9.53 mg/g.
FLUID FLOW BODIES FOR THE PULP AND PAPER INDUSTRY
Authors: Alashkevich Yuriy Davidovich , Lur'e Mikhail Semenovich , Lur'e Ol'ga Mikhaylovna , Frolov Aleksandr Sergeyevich 
Published: January 2021

The question of the use of vortex flowmeters with different versions of the flow body (TO) under operating conditions on the technological lines of pulp and paper production is considered.
It is shown that when using different TO in vortex flowmeters, an error occurs in the working range of speeds (flow rates). The observed error arises due to a change in the Strouhal number (Sh) and is associated with the measurement method. In this case, the Strouhal number begins to depend not only on the TO used as a vortex generator, but also on the flow velocity and the concentration of the fibrous suspension. As the main comparative factor for the investigated TOs, the force action on the sensitive element (flexible electrode) located inside the TO was taken.
The study was carried out in several stages using numerical modeling and experimental design method. According to the results of a numerical study, the dependence of the Strouhal number (Sh) on the flow rate (V) and the concentration of the suspension (c) is presented.
In a comparative analysis of the deviation of the Strouhal number from the average values, it was revealed that MOT No. 1 has a minimal effect on the concentration of the suspension in the working range of flow rates (± 0.5%). This circumstance makes it possible to verify and test flow meters with such maintenance in conventional pouring installations.
The analysis of the maintenance with respect to the signal-to-noise ratio shows that the purest signal is generated by the cylindrical maintenance (maintenance No. 3), and maintenance No. 2 and No. 1 have noticeably large noise. The differences are explained by the absence on the surface of a cylindrical TO of extra protrusions, faces, which leads to a smoother flow of a suspension around its surface, as well as to a decrease in internal spurious noise.
PREPARATION OF WOOD FIBER SEMI-FINISHED PRODUCTS IN KNIFE MACHINES OF VARIOUS MODIFICA-TION
Authors: Chistova Natal'ya Geral'dovna , Matygulina Venera Nurullovna , Alashkevich Yuri Davydovich 
Published: January 2021

In this paper, we consider the results of a study of the influence of the design and technological parameters of grinding machines of various modifications on the quality of wood pulp.
According to the results of processing multifactor experiments implemented according to the second-order B-plan, a mathematical description was obtained of the dependence of the degree of grinding of pulp on the gap between the grinding disks, wear of the segments, the rotational speed of the lower screw and the concentration of pulp. The obtained regression models are adequate to the process and can be applied in practice for predicting the qualitative characteristics of wood pulp depending on the parameters of the grinding process.
Analyzing the obtained experimental data, it can be noted that such factors as the state of the surfaces of grinding disks, the gap between them and the concentration of wood fiber have the greatest influence on the degree of grinding of the mass. Evaluation of graphical dependencies allows you to determine the extent to which you can vary the operating and design parameters of the grinding process to obtain wood fiber with the required grinding quality.
DEPENDENCE OF STRENGTH OF FIBERBOARDS FROM TERMS OF PREPARATION OF WOOD FIBER SEMI-FINISHED PRODUCTS
Authors: Matygulina Venera Nurullovna , Chistova Natalya Geraldovna , Vititnev Alexander Yuryevich 
Published: January 2021

Despite the reduced demand for fiber boards, research related to their manufacture is relevant, since the production of wood-based materials significantly contributes to solving the problem of the integrated use of wood raw materials.
The paper presents the results of experimental studies reflecting the dependence of the strength characteristics of dry and wet wood fiber boards on the structural and technological parameters of grinding plants of various modifications. The experiments were carried out in laboratory facilities and in the production environment on existing industrial equipment. Based on the results of processing multifactor experiments implemented in a second-order B plan, a mathematical description was obtained of the dependence of the tensile strength during static bending of solid wood fiber boards of the dry and wet production method on the gap between the grinding disks, wear of the segments and the concentration of wood fiber mass. The obtained regression models are adequate to the process and can be applied in practice to predict the strength characteristics of fiberboards depending on the parameters of the grinding process.
As a result of the analysis of the calculated and graphical dependences obtained on the basis of studies in the production environment on the existing equipment, it is possible to determine what parameters on the grinding equipment must be set in order to obtain the necessary physical and mechanical properties of the fiberboard.