bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impacto del fenómeno de migración de estadio ganglionar en la supervivencia y la recurrencia de pacientes con cáncer papilar de tiroides sometidos a vaciamiento ganglionar profiláctico
Authors: Agamez-Fuentes José Eduardo , Sanabria Quiroga Álvaro Enrique 
Published: August 2021

Introducción. Dado que un ensayo clínico aleatorio es irrealizable, el rol del vaciamiento ganglionar profiláctico en pacientes con cáncer papilar de tiroides sin comprobación clínica de compromiso ganglionar metastásico (cN0) es controversial. El vaciamiento ganglionar profiláctico acarrea un proceso de reclasificación de pacientes, al hacer evidente la positividad ganglionar micrometastásica antes ignorada, lo que genera una aparente pero falsa mejoría en los desenlaces de los grupos de estadificación, mientras el pronóstico individual y total de la población no cambia, fenómeno conocido como migración de estadio o fenómeno de Will Rogers.
Métodos. Se ejecutaron simulaciones de poblaciones con cáncer papilar de tiroides con compromiso ganglionar metastásico clínicamente evidente (cN+) y cN0, para determinar el impacto del fenómeno de migración de estadio en los pacientes sometidos a vaciamiento ganglionar profiláctico.
Resultados. Con la simulación de las poblaciones y sus estadios ganglionares, se observa cómo la migración de estadio ganglionar genera una aparente mejoría en los desenlaces de recurrencia loco regional y supervivencia, sin cambiar los desenlaces de la población total ni individuales.
Discusión. El fenómeno de migración de estadio es uno de los sesgos más importantes que limitan el uso de grupos históricos de control en ensayos de tratamiento experimental. De acuerdo con nuestros resultados, este fenómeno podría explicar los beneficios observados con el vaciamiento ganglionar profiláctico en algunos de los estudios agregativos publicados hasta el momento, hallazgos que no han sido documentados para el cáncer papilar de tiroides.
Considerations for supporting Canadian military-connected students in K-12 and higher education
Authors: Hill Shannon , Cathcart Darryl G. 
Published: August 2021

LAY SUMMARY Within Canada, little is known about the educational experiences of military-connected students in the K-12 and higher education systems. American research has been published and provides insight into the unique challenges that military-connected students can experience in such contexts. Because of the lack of research conducted in Canada to date, it is unclear if American research findings represent the educational experiences of Canadian military-connected students in K-12 and higher education. This article discusses how identification of military-connected students, as well as educator awareness, or lack thereof, are creating organizational challenges in the Canadian context for supporting military-connected students in K-12 and higher education.
Philology training at the university in the light of the systematic approach
Authors: Bosa Vita 
Published: August 2021

The article describes the peculiarities of applying a systematic approach to the training of future philologists in universities.
The research goal is to clarify the methodological features of a systematic approach to the philologist training in a modern university. The research methods are the scientific analysis, systematization, classification, modeling.
Results. The main factors determining the need for a systematic approach have been identified (the common sociocultural processes in the language environment of many countries lead to linguistic unification (formerly English-speaking) and to preservation of their linguistic identity as the basis for national identity; the increase of the level of individual mobility, in the field of education including, development of polylingual, bilingual and multicultural links in education; new challenges and risks in the area of professional training related to the digitalization and dissemination of online education models in the context of global pandemics and the distance education segment expansion). Moreover, basing on the analysis of scientific sources (methodological bases for the training of philologists; contents and basic models of the training of these specialists; ICT as a systematic resource for the training of philologists), the opinion about the necessity of application of pedagogical systemology to the professional training of students-philologists in university conditions is substantiated. The analysis of the pedagogical and linguistic segments of systemology made it possible to identify the leading systemic characteristics of the training of philologists at the university (essence, composition, structure, functions, history of the system) and to investigate the manifestation of the systemic characteristics of the studied phenomenon in the conditions of the university environment as a systemic object. It is noted that the training of future philologists at the university as a system is synergistic; the professional training of philologists at the university as a system object is characterized as a complex open dynamic purposeful system with characteristics of continuous self-organization.
Conclusions. It was concluded that the training of philologists as a complex system involves a certain number of structural components (content, human resources, information, technological resources) for its functioning; the system is open-ended (to other pedagogical systems) in its nature, complementarity and interconnection with the scientific and technological systems implemented in other areas of training. It has been proved that the systematic characteristics of the training of specialists in the field of philology are provided by the specific guidelines for the establishment, operation and development of this system; the objectives of the above-mentioned specialists’ training determine its content and end result, that is a competent specialist in his or her professional field and qualified in the professional activity, capable of self-education and self-development.
The Family Thought of Marx and Engels and Its Enlightenment in the New Era
Authors: Wang Tingting 
Published: August 2021

In the Marxist theoretical system, "family" is a very important theoretical category, which is not only the "mystery" Marx and Engels has been trying to solve, but also an important reflection of Marxist philosophy. Marx and Engels held the conviction that the development of the family went through the consanguinity family, the Punaluian family, the paring family and the monogamous family. Marital relationship is the basis of forming a family; blood relationship is the bond of forming a family; family is the organizational form of human social life. Those are the essential characteristics of family. In the new era, while promoting the harmonious development of family, we must know the harmonious marriage relationship is the foundation of family harmony, and that the harmonious parent-child relationship is the key to family harmony. Meanwhile, we should pay attention to the harmonious unity of family and society.
Gastrointestinal Yerleşimli Lipomalar: 19 Olgunun Retrospektif Analizi
Authors: ÖZŞEN Mine , YERCİ Ömer , UĞRAŞ Nesrin , IŞIK Özgen , YILMAZLAR Tuncay 
Published: August 2021

Özet
Bu tanımlayıcı çalışmada gastrointestinal sistem yerleşimli lipoma tanılı olgularının sunulması ve bu tümörlerin klinikopatolojik özelliklerinin literatür bilgileri eşliğinde değerlendirilmesini amaçlanmıştır. Çalışmamızda Tıbbi Patoloji Anabilim Dalı arşivi taranarak gastrointestinal sistem yerleşimli lipoma tanılı 19 olgu retrospektif olarak incelendi. Gastrointestinal sistem yerleşimli lipoma tanısı almış toplam 19 olgu tespit edildi. Olguların 11'i kadın (%57,9), 8'i erkekti (%42,1). Olguların yaş dağılımı 36-78 yaş arasında değişmekte olup, ortalama yaş değeri 62,3+9 yaş olarak saptandı. 19 olgunun 1'i mide, 3'ü ince barsak, 14’ü kolon ve 1'i rektum yerleşimliydi. Angiolipoma tanısı alan inen kolon yerleşimli tek olgu dışında kalan tüm olgular klasik lipoma morfolojsindeydi. Genellikle insidental olarak saptanan lipomalar, obtrüksiyon, intrususepsiyon ve kanama gibi ciddid gastrointestinal semptomlara yol açabilen, adenokarsinomalara eşlik edebilen ve malignitelerle ayırıcı tanısı yapılması gereken tümörlerdir. Tüm olgular operasyon öncesinde uygun radyolojik ve endoskopik yöntemlerle incelenmeli ve her olgu için en uygun tedavi seçeneği değerlendirilmelidir.
MASSAGE COUNTER PRESSURE MEMPENGARUHI INTENSITAS NYERI HAID PADA REMAJA PUTRI
Authors: Henniwati Henniwati , Dewita Dewita 
Published: August 2021

MASSAGE COUNTER PRESSURE AFFECT THE INTENSITY OF HAART PAIN IN ADOLESCENT PRINCESS Background: Menstrual pain is pain that almost all women feel during menstruation. In Indonesia, the incidence of dysmenorrhea is 64.25%. Treatments that can be given to reduce menstrual pain are suggested pharmacologically and non-pharmacologically. One of the non-pharmacological therapies that can be given is the counter pressure technique.Purpose: This study aims to determine the effect of counter pressure on the intensity of menstrual pain in adolescent girls.Method: the type of research used is a quasi-experimental design with a pretest-posttest one group design. The sampling technique used total sampling technique, the number of samples in this study were 36 young women at SMPN 9 Langsa City.Results: The results of the study were obtained at the pretest time the severe pain scale was 50%, and at the posttest after being given the treatment the pain scale decreased to a mild pain scale of 83.3%. The results of the Paired T-Test analysis showed that there was an effect of counterpressure on the intensity of menstrual pain in adolescent girls with a sig. 0,000.Conclusion: The couter pressure technique affects the intensity of menstrual pain in adolescent girls (P = 0,000).Suggestion: IUKS department in schools can provide counter pressure therapy to reduce menstrual pain that is felt by young women. Keywords: Menstrual Pain, Counter pressure,Adolescent ABSTRAK Latar Belakang : Nyeri haid merupakan nyeri yang hampir seluruh wanita rasakan pada saat haid. Di Indonesia angka kejadian dismenore sebesar 64,25%. Penanganan yang dapat diberikan untuk mengurangi nyeri haid yang disarakan secara farmakologi dan nonfarmakologi. terapi nonfarmakologi yang dapat diberikan salah satunya adalah tehnik counter pressure.Tujuan : penelitian ini bertujuan untukmengetahui pengaruh pemberian counter pressure terhadap intensitas nyeri haid pada remaja putri.Metode: jenis penelitian yang digunakan yaitu quasi eksperimendengan densain pretest- posttest one group desain. tehnikpengambilansampelmenggunakan Tehniktotal Sampling, jumlahsampel pada penelitian ini yaitu 36 remaja putri di SMPN 9 Kota Langsa.Hasil saat pretest skala nyeri berat sebesar 50%, dan pada saat posttest setelah diberikan perlakuan skala nyeri turun menjadi skala nyeri ringan 83,3%. Hasil analisis Paired T-Test menunjukan ada pengaruh pemberiaan counter pressure tehadap intensitas nyeri haid pada remaja putri denga nilai sig. 0,000.Kesimpulan : Tehnik counter pressure berpengaruh terhadap intensitas nyeri haid pada remaja putrid (P = 0,000).Saran : UKS di sekolah agar dapat memberikan terapi counter pressure untuk mengurangi nyeri haid yang dirasakan remaja putri. Kata Kunci : Nyeri Haid, Counter pressure,remaja
O PLÁGIO NOSSO DE CADA DIA
Authors: Bezerra Eridene Bezerra 
Published: August 2021

Este trabalho tem como objetivo apresentar um estudo de caso que foi baseado em situação real ocorrida durante o ensino remoto, em virtude do distanciamento social, necessário para combater a pandemia causada pelo COVID-19. Para isso, foi realizada uma revisão de literatura através de uma pesquisa bibliográfica em artigos e sites da internet, com o intuito de produzir um estudo de caso, detalhando todas as etapas, possibilitando a sua aplicação em aulas de Língua Portuguesa, em ambiente virtual. Desse modo, o referido caso problematiza o plágio nas produções escritas solicitadas aos estudantes do ensino médio integrado à Educação Profissional e Tecnológica. Para isso, busca-se fundamentação teórica na bibliografia que discorre sobre os temas abordados pela investigação. Assim, recorre-se aos estudos de Queiroz (2015) que apresenta uma perspectiva bastante didática para a produção de estudo de casos voltados para o ensino médio. Reporta-se também a autores como Borgianni (S/A) e Antonio (2015) que fazem uma discussão bastante atual acerca do plágio. Conclui-se que a temática levantada pelo caso em questão mostra-se bastante relevante para o processo de ensino-aprendizagem.
Long-Term Population Fluctuations of A Burrowing Owl Population On Kirtland Air Force Base, New Mexico, USA
Authors: Lundblad Carl G. , Conway Courtney J. , Cruz-McDonnell Kirsten , Doublet Dejeanne , Desmond Martha J. , Navis Corrie J. , Ongman Kurt 
Published: August 2021

Abstract
Western Burrowing Owls (Athene cunicularia hypugaea; hereafter, Burrowing Owls) were once widespread residents of grasslands throughout western North America, but their range has contracted, and abundance has declined in some regions. The causes of declines and geographic variation in population trends of Burrowing Owls are unclear but may be linked to changing land use and urbanization. Burrowing Owls are often found in association with airfields and airports, and their presence at such facilities is sometimes considered to be in conflict with those operations. Documenting the long-term persistence of Burrowing Owls at active airfields can help airfield managers who face decisions regarding compatibility of owls and airfield operations. We report the results of a long-term effort to monitor Burrowing Owls on Kirtland Air Force Base in New Mexico, USA, including the rapid recovery of Burrowing Owl numbers from near-extirpation and the relationships between abundance and other demographic traits. The number of breeding pairs of Burrowing Owls increased from one pair in 2013 to 28 pairs in 2019 and 2020, and the number of fledglings produced increased from one in 2013 to 84 in 2019 and 61 in 2020. The recovery was not uniform across all areas of Kirtland Air Force Base, and some formerly occupied areas remained unoccupied. We documented dispersal outside the Air Force base boundary and that the number of breeding pairs was more strongly influenced by the number of offspring produced in the prior year than the number of owls returning from prior years, which indicated that the population is part of a larger meta-population. Our results demonstrate that the maintenance of Burrowing Owl populations is not necessarily at odds with safe airfield operations, that Burrowing Owls exhibit complex population dynamics, and can rapidly recolonize previously occupied areas if habitat and nest sites remain suitable.
FRAGMENTASI IDENTITAS DALAM NOVEL BUKAN CINTA SESAAT KARYA MIRA WIDJAJA
Authors: Burhan Faika 
Published: August 2021

Penelitian ini bertujuan untuk mendeskripsikan fragmentasi identitas dalam novel Bukan Cinta Sesaat karya Mira Widjaja. Metode yang digunakan dalam penelitian ini adalah deskriptif kualitatif. Pengumpulan data dilakukan dengan studi pustaka, sedangkan metode analisis menggunakan teori identitas dengan melihat fenomena-fenomena yang terkait dengan fragmentasi identitas itu sendiri. Hasil penelitian menunjukkan Mira Widjaja dalam novel Bukan Cinta Sesaat menunjukkan gejala kekerasan dan diskriminasi rasial terhadap etnis Tionghoa. Meskipun mengalami kekerasan dan diskriminasi tokoh Nina dihadirkan sebagai perempuan Tionghoa yang kuat dan berupaya menghadapi kerasnya hidup sebagai etnis minoritas. Kekerasan dan diskriminasi tersebut menyebabkan terjadinya fragmentasi identitas. Identitas yang terbangun adalah identitas yang terpecah-belah diakibatkan oleh situasi. Dalam hal ini, identitas yang terpecahbelah tersebut dialami oleh warga etnis Tionghoa seperti yang diceritakan di dalam novel. Adapun bentuk fragmentasi identitas yang muncul dalam novel ini yakni kecemasan dan keterasingan individu terhadap lingkungan sosialnya.
Abnormal Functional Connectivity of Posterior Cingulate Cortex Correlates With Phonemic Verbal Fluency Deficits in Major Depressive Disorder
Authors: Li Danian , Zhang Hanyue , Liu Yujie , Liang Xinyu , Chen Yaoping , Zheng Yanting , Qiu Shijun , Cui Ying 
Published: August 2021

Background: Major depressive disorder (MDD) patients face an increased risk of developing cognitive impairments. One of the prominent cognitive impairments in MDD patients is verbal fluency deficit. Nonetheless, it is not clear which vulnerable brain region in MDD is interactively linked to verbal fluency deficit. It is important to gain an improved understanding for verbal fluency deficit in MDD.Methods: Thirty-four MDD patients and 34 normal controls (NCs) completed resting-state fMRI (rs-fMRI) scan and a set of verbal fluency tests (semantic VFT and phonemic VFT). Fourteen brain regions from five brain networks/systems (central executive network, default mode network, salience network, limbic system, cerebellum) based on their vital role in MDD neuropathology were selected as seeds for functional connectivity (FC) analyses with the voxels in the whole brain. Finally, correlations between the z-score of the FCs from clusters showing significant between-group difference and z-score of the VFTs were calculated using Pearson correlation analyses.Results: Increased FCs in MDD patients vs. NCs were identified between the bilateral posterior cingulate cortex (PCC) and the right inferior frontal gyrus (triangular part), in which the increased FC between the right PCC and the right inferior frontal gyrus (triangular part) was positively correlated with the z score of phonemic VFT in the MDD patients. Moreover, decreased FCs were identified between the right hippocampal gyrus and PCC, as well as left cerebellum Crus II and right parahippocampal gyrus in MDD patients vs. NCs.Conclusions: The MDD patients have altered FCs among key brain regions in the default mode network, the central executive network, the limbic system, and the cerebellum. The increased FC between the right PCC and the right inferior frontal gyrus (triangular part) may be useful to better characterize pathophysiology of MDD and functional correlates of the phonemic verbal fluency deficit in MDD.
Maslinic Acid Attenuates Denervation-Induced Loss of Skeletal Muscle Mass and Strength
Authors: Yamauchi Yuki , Ferdousi Farhana , Fukumitsu Satoshi , Isoda Hiroko 
Published: August 2021

Maslinic acid (MA) is a pentacyclic triterpene abundant in olive peels. MA reportedly increases skeletal muscle mass and strength in older adults; however, the underlying mechanism is unknown. This study aimed to investigate the effects of MA on denervated muscle atrophy and strength and to explore the underlying molecular mechanism. Mice were fed either a control diet or a 0.27% MA diet. One week after intervention, the sciatic nerves of both legs were cut to induce muscle atrophy. Mice were examined 14 days after denervation. MA prevented the denervation-induced reduction in gastrocnemius muscle mass and skeletal muscle strength. Microarray gene expression profiling in gastrocnemius muscle demonstrated several potential mechanisms for muscle maintenance. Gene set enrichment analysis (GSEA) revealed different enriched biological processes, such as myogenesis, PI3/AKT/mTOR signaling, TNFα signaling via NF-κB, and TGF-β signaling in MA-treated mice. In addition, qPCR data showed that MA induced Igf1 expression and suppressed the expressions of Atrogin-1, Murf1 and Tgfb. Altogether, our results suggest the potential of MA as a new therapeutic and preventive dietary ingredient for muscular atrophy and strength.
When the Leader is Born as A Competitor (WLBC)
Authors: Maulana Agus , Maulana Raju 
Published: August 2021

The presence of humans on earth is a gift of leadership and humans are born with their destiny as leaders for themselves, their families, and the surrounding community. The challenges that are faced every day are important factors in shaping the character of one's self and soul so that it has implications for a leader when taking part in society. Jokowi as a figure of a leader who was forced by circumstances, his family, and society formed himself into a leader with a different character, and it is said that an expert is a Servant Leader. Methodology qualitative and narrative descriptive analysis methods on literature review. Comparisons of expert opinions and theories as well as relating several important events in the lives of characters through audio and video as well as real-life stories. Jokowi's leadership has become an inspiration for many people so that the author is interested in seeing and observing more deeply from the historical side of Jokowi, from the selectivity of a biography and the history of success as a company leader, major, governor and president, this is also what makes the writer's way of thinking finding a new view of leadership theory which is referred to in the term WLBC, along with the many theories of styles and characteristics and types of leadership by previous experts, writers and researchers. There are three finding factors that strongly influence the formation of Jokowi's character which are applied in ten indicators, three factors including family, community, and personal responsibility.
Effect of Roundup Herbicide on Digestion in Fish (Review)
Authors: Голованова И.Л. 
Published: August 2021

Дан краткий обзор современной литературы по влиянию Раундапа – неселективного глифосатсодержащего гербицида широкого спектра действия на физиолого-биохимические показатели рыб. Особое внимание уделено воздействию гербицида в условиях in vivo и in vitro на активность пищеварительных ферментов рыб, обитающих в водохранилищах Верхней Волги. Продемонстрирована зависимость силы и направленности эффектов от вида, возраста и типа питания рыб, концентрации гербицида и условий эксперимента, а также действия ряда антропогенных факторов.
A brief overview of the modern literature on the influence of Roundup – a non-selective glyphosate-containing herbicide of a wide spectrum on the physiological and biochemical indicators of fish is given. Particular attention is paid to the effect of herbicide in vivo and in vitro on the activity of digestive ferments of fish living in reservoirs of the Upper Volga. The dependence of the strength and orientation of the effects on the species, age and type of nutrition of fish, the concentration of the herbicide and the experimental conditions, as well as the actions of a number of anthropogenic factors has been demonstrated.