bluuebunny/crossref_metadata_2025_split huggingface dataset:
Astaxanthin Attenuates Adiponectin, Calprotectin, miRNA222 and
miRNA378 in Obesity induced by High-Fat Diet in Rats
Authors: Boshra Sylvia A. 
Published: August 2021

Background:
Astaxanthin suppressed obesity in rats fed with high-fat diet (HFD) via the restriction of adipose tissue build-out, therefore, improving insulin sensitivity and inflammation. Metformin reduces insulin resistance and may reduce weight.

Aim:
Investigation of the effects of astaxanthin and metformin in obesity prompted by a high-fat diet.

Objective:
The present article investigates the effects of astaxanthin and metformin in obesity prompted by a high-fat diet in rats through measuring miRNA222 and 378.

Materials:
The rats were classified into four classes containing ten albino rats each: Group I (Normal group): nourished with ordinary diet for 8weeks. Group II (Control positive): nourished with a high-fat diet for 8 weeks. Group III: nourished with astaxanthin (50mg/kg)(1/40 LD50) orally plus a high-fat diet for 8weeks. Group IV: nourished with metformin (500mg/kg) orally plus a high-fat diet for 8 weeks.

Methods:
Leptin, adiponectin, calprotectin and interleukin 6 (IL-6) were assessed by rat-specific ELISA kits. Tumor necrosis factor-alpha (TNF-α), miRNA222 and miRNA378 expressions were quantified by quantitative real-time PCR.

Results:
Astaxanthin and metformin have anti-obesity and antioxidant actions and significantly decreased the weight of the body, glucose, insulin, triglycerides, total cholesterol, triglycerides and leptin, as well as plasma calprotectin & IL-6 and increased HDL-C and adiponectin. The liver TNF-α gene expression, adipose tissue miRNA222 and miRNA378 expression were decreased compared to HFD control rats.

Discussion and Conclusion:
Astaxanthin has regulated the aberrant expression of miRNA222 and 378 that may be related to hyperlipidemia and insulin resistance. Accordingly, astaxanthin deserves a clinical trial in the future due to its effects on miRNAs involved in obesity.
Reducing the spread of the Coronavirus (COVID-19) In light of the Islamic Law and scientific approach: Protection, and prevention
Authors: Ghidan Huda Y , Ghidan Alaa Y , Ahmed Hytham M 
Published: August 2021

A virus is an ultramicroscopic (20-300 nanometers in diameter) metabolically inert, infectious agent that replicates only within the cells of living hosts. Coronavirus disease 2019 (COVID-19) is a viral infectious disease caused by SARS-CoV-2 and is announced by World Health Organization (WHO) as a pandemic. As of 23 August 2020, 23,407,334 infected people and 810,242 deaths were reported worldwide. COVID-19 has affected our daily lives and influences all aspects of life, including economic, social, health, etc. On the healthcare level, the world is faced with many challenges, including diagnosis, quarantine, and treatment of suspected cases, overloaded doctors and healthcare professionals and the requirement of a high level of protection. This research focused on preventive measures - preventive medicine - to combat coronavirus according to Islamic law's and modern medicine's perspective. Sharia focuses on preserving diseases to achieve its objectives thereby, so it has legislated some of the rulings that achieve this purpose, so it based its provisions on bringing interests and warding off evil. This research has been divided into two requirements; the first requirement is that the researcher talked about preventive strategies, one of the most important branches of medicine because it precedes disease before it occurs to be rectified with awareness and guidance. The second requirement: supporting scientific research to make vaccines and medicines is the most important findings of the researcher. Besides the review intent to explaining the extent of compatibility and difference between practical applications in Islamic jurisprudence and modern medicine, Explaining the importance of treatment from diseases and epidemics and the necessity of supporting scientific research to find medicines and vaccines( not only preventive strategies), and A statement of the importance and necessity of adhering to the instructions and instructions issued by the competent medical authorities and institutions with expertise and competence to prevent transmission of infection by prevention, treatment and taking vaccinations.
Perceptions of Alerts Issued by Social Media Platforms in Response to Self-injury Posts Among Latinx Adolescents: Qualitative Analysis
Authors: Laestadius Linnea I , Craig Katherine A , Campos-Castillo Celeste 
Published: August 2021

BackgroundThere is growing interest in using social media data to detect and address nonsuicidal self-injury (NSSI) among adolescents. Adolescents often do not seek clinical help for NSSI and may adopt strategies to obscure detection; therefore, social media platforms may be able to facilitate early detection and treatment by using machine learning models to screen posts for harmful content and subsequently alert adults. However, such efforts have raised privacy and ethical concerns among health researchers. Little is currently known about how adolescents perceive these efforts.ObjectiveThe aim of this study is to examine perceptions of automated alerts for NSSI posts on social media among Latinx adolescents, who are at risk for NSSI yet are underrepresented in both NSSI and health informatics research. In addition, we considered their perspectives on preferred recipients of automated alerts.MethodsWe conducted semistructured, qualitative interviews with 42 Latinx adolescents between the ages of 13 and 17 years who were recruited from a nonprofit organization serving the Latinx community in Milwaukee, Wisconsin. The Latinx population in Milwaukee is largely of Mexican descent. All interviews were conducted between June and July 2019. Transcripts were analyzed using framework analysis to discern their perceptions of automated alerts sent by social media platforms and potential alert recipients.ResultsParticipants felt that automated alerts would make adolescents safer and expedite aid before the situation escalated. However, some worried that hyperbolic statements would generate false alerts and instigate conflicts. Interviews revealed strong opinions about ideal alert recipients. Parents were most commonly endorsed, but support was conditional on perceptions that the parent would respond appropriately. Emergency services were judged as safer but inappropriate for situations considered lower risk. Alerts sent to school staff generated the strongest privacy concerns. Altogether, the preferred alert recipients varied by individual adolescents and perceived risks in the situation. None raised ethical concerns about the collection, analysis, or storage of personal information regarding their mental health status.ConclusionsOverall, Latinx adolescents expressed broad support for automated alerts for NSSI on social media, which indicates opportunities to address NSSI. However, these efforts should be co-constructed with adolescents to ensure that preferences and needs are met, as well as embedded within broader approaches for addressing structural and cultural barriers to care.
Bridging the Gap: Introduction of an Antimicrobial Peripherally Inserted Central Catheter (PICC) in Response to High PICC Central Line-Associated Bloodstream Infection Incidence
Authors: DeVries Michelle , Sleweon Thomas 
Published: August 2021

Highlights

Abstract
Objective: To reduce the incidence of central line-associated bloodstream infection (CLABSI) in peripherally inserted central catheters (PICC) through the introduction of an antimicrobial (AM) catheter as recommended in evidence-based guidelines and standards.
Design: Quality improvement project comparing incidence of infections pre-implementation and postimplementation of the new catheter.
Setting: A 582-bed community teaching hospital in Northwest Indiana.
Methods: Pre-implementation analysis of surveillance data indicated that 50% of CLABSIs occurred in patients with PICCs in situ. A gap analysis was performed to review institutional practices against evidence-based recommendations. The use of an AM catheter was supported in each of the documents consulted. After introduction of the new device, performance was measured in a prospective manner using standardized Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) surveillance protocols for CLABSI and internal data sources for other measures.
Results: After 30 months of data collection, the PICC CLABSI incidence reduced from a baseline rate of 1.83/1000 PICC days to 0.162/1000 PICC days (91.15% reduction, P = 0.0002).
Conclusion: Combined with continued compliance with basic prevention strategies (i.e., use of a central line insertion checklist/insertion bundle) and optimization of device selection and lumen justification, the introduction of an antimicrobial/antithrombogenic (AM/AT) PICC was associated with a significant reduction in CLABSI.
Tradisi Jamaahan Empat Puluh Hari Kajian Living Hadis Di Desa Jatipurus Kecamatan Poncowarno Kabupaten Kebumen
Authors: Wakhid Nur 
Published: August 2021

The tradition of forty-five-day congregation was developed by the creativity of religious figures in Jatipurus Village as a persuasive approach in order to promote the sharia of congregational prayer within the society. To support the arguments of that tradition, they combined the hadith encouraging forty-day congregational prayer with the hadith commanding to increase worship during the sacred months (glorified months). The practice of this congregational prayer was established in one of the sacred months, it was arranged from the 20th of Dzulhijjah to the 30th of Muharram. There was a strong correlation and combination between the charismatic religious figures and the hadith. It was proven by the enthusiastic involvement of Jatipurus society during the forty-five-day congregation that was arranged annually; as a sequence, it was recognized as a tradition. The fundamental part of that tradition was tasyakuran in which it was engaged in the activities of tahlil, religious talks, prayers, and then it was ended by having meals together. That tradition was investigated and analyzed by implementing Karl Mannheim’s theory on the sociology of knowledge. The concentration of this research was related to three aspects of meaning. The first, the objective meaning: it showed that the people of Jatipurus believed that the tradition of forty-five-day congregation was a legacy of their predecessors. The second, the expression meaning: the society who joined the congregation believed that by consistently performing the forty-five-day congregation could save them from two things: the torment of the fire and hypocrisy. Finally, the third, the documentary meaning: they did not realize the implied meaning of the tradition, in which the implementation of the forty-five-day congregation was an expression of a religious culture.
Experiencia de Catuai Amarillo en el marco de la producción orgánica y el comercio justo
Authors: Escamilla Prado Esteban 
Published: August 2021

En las tres últimas décadas, en un contexto de neoliberalismo, el sector cafetalero mexicano está enfrentando diversos problemas ocasionados por los bajos precios, afectaciones fitosanitarias y cambio climático. A pesar de estas adversidades algunas organizaciones de pequeños productores se mantienen produciendo y comercializando cafés diferenciados o certificados. Catuai Amarillo es una organización ubicada en Chocamán, Veracruz, constituida en 1990. En los 30 años de desarrollo organizacional se identifican tres etapas. En la primera se avanza hacia el valor agregado, de “cereceros” se transforman en “pergamineros”; la segunda se caracteriza por la diferenciación del producto mediante la certificación orgánica y el comercio justo para la exportación de café verde a Estados Unidos y Europa; y la tercera la búsqueda de cafés especiales con mayor participación en el mercado nacional con café tostado y molido. Otras acciones importantes son diversificación productiva, alianzas estratégicas y relevo generacional. A pesar de los logros, aún persisten importantes desafíos.
ROMPENDO O SILÊNCIO: A IMPORTÂNCIA DA RESISTÊNCIA DAS MULHERES CONTRA AS DITADURAS NO BRASIL E NA ARGENTINA
Authors: Lucas Doglas Cesar , Oliveira Carla Dóro de 
Published: August 2021

A história das mulheres é, não raras vezes, esquecida e desvalorizada, ainda mais quando se fala nos regimes ditatoriais vividos pelos países do Cone Sul. Assim, dando especial foco para o Movimento Feminino pela Anistia (MFA) e para a associação das Madres e Abuelas de Plaza de Mayo, este trabalho se propõe a analisar a participação das mulheres na organização de grupos civis de proteção aos direitos humanos durante o período autoritário vivido no Brasil e na Argentina. Para mais, procurou-se entender como tais organizações surgiram, como atuaram e quais foram as consequências dessa mobilização. Na metodologia utilizou-se pesquisa bibliográfica, numa abordagem qualitativa, abrangendo a leitura e análise de obras doutrinárias e artigos. Os resultados do trabalho apontam que a participação das mulheres na luta contra repressão foi inovadora, pois ia de encontro ao que se esperava da mulher nas décadas de 1960 e 1970. Apesar da pouca importância dada pelas narrativas históricas para esses grupos de mulheres, observa-se que sua atuação foi de fundamental importância para a superação do regime autoritário nos países estudados.
A importância da abordagem da saúde nas escolas após a pandemia de COVID-19: uma revisão bibliográfica
Authors: Nunes Marcus Antonius da Costa , Santos Vanessa dos Reis , Moreira Dilma Josefa de Souza , Rosa Karolyna Freitas , Sedano Liciane de Souza Araújo , Costa Vanuza Nunes Sedano 
Published: August 2021

Objetivo: Revisar, através da literatura existente, a importância de se abordar questões de saúde nas escolas após a pandemia do novo coronavírus. Revisão bibliográfica: No início do ano de 2020 estourou em proporções globais a infecção por uma nova doença altamente contagiosa, a Covid-19 (Coronavirus Disease 2019), causada pelo Coronavírus. A capacidade de propagação da doença além do resultado das investigações que apontam o surgimento da doença através do consumo de carne de animal crua, reacende uma velha discussão acerca de como se instruir a população para evitar o surgimento de novos vírus letais e como desenvolver uma cultura preventiva baseada na higiene. O ambiente escolar surge como alternativa para a disseminação de conhecimentos referentes a temática, além de ser o principal meio de acesso do Estado aos planos sociais imprescindíveis para a manutenção da vida humana no futuro. Considerações finais: Estabelecer planos educacionais voltados a higiene e a boa alimentação consiste em trabalhar de forma preventiva para evitar o surgimento de novos vírus como o da Covid-19, além de ser também uma alternativa reforçar a bandeira ambiental nas salas de aula visando estimular o contato humano com a natureza e promover um conhecimento mais apurado acerca das novas possibilidades.
PELATIHAN OPERASIONAL PERBANKAN SYARIAH BAGI KSPPS BMT PENITI KAHURIPAN MULIYA
Authors: Khalifaturofi'ah Sholikha Oktavi , Adiba Elfira Maya , Nasution Zubaidah 
Published: August 2021

<pre> </pre><p><strong>Abstract</strong>. One of the problems in Islamic microfinance institutions is the availability of human resources who understand and are qualified in Islamic banking operations. The development of professionalism of lecturers in the field of teaching regarding Islamic bank operation laboratories has been related to the problem of lack<br />of understanding of human resources in BMT. The purpose of this activity is to provide training on Islamic banking operations. This training was attended by 5 employees of KSPPS BMT Peniti Kahuripan Muliya. The training participants came from three BMT branch offices, namely the Surabaya branch, the Boyolali<br />branch, and the Bandung branch. The methods used are 1) providing theoretical and practical knowledge about Islamic banking operations 2) assistance in the roleplay of Islamic banking operations. The results of this activity are: First, all participants of this training activity are very enthusiastic and highly motivated to participate in the implementation of Islamic banking operational training activities. Second, the participants who attended the training as a whole were 60% of all training participants.<br /><br /></p><p><strong><br /></strong></p><p><strong>Abstrak</strong>. Salah satu masalah dalam lembaga keuangan mikro syariah adalah ketersediaan SDM yang memahami dan mumpuni dalam operasional perbankan syariah. Pengembangan profesionalisme dosen pada bidang pengajaran tentang laboratorium operasi bank syariah selama ini terkait dengan persoalan kurangnya pemahaman SDM di BMT. Tujuan kegiatan ini adalah untuk memberikan pelatihan tentang operasional perbankan syariah. Pelatihan ini diikuti oleh para karyawan KSPPS BMT Peniti kahuripan Muliya sebanyak 5 orang. Peserta pelatihan berasal dari tiga kantor cabang BMT yaitu cabang Surabaya, cabang Boyolali, dan Cabang Bandung. Metode yang digunakan adalah 1) pemberian pengetahuan teoretis dan praktis tentang operasional perbankan syariah 2) pendampingan dalam <em>roleplay</em> operasional perbankan syariah. Hasil kegiatan ini adalah : Pertama, semua peserta kegiatan pelatihan ini sangat antusias, bersemangat, dan mempunyai motivasi yang tinggi mengikuti pelaksanaan kegiatan pelatihan operasional perbankan syariah. Kedua, peserta kegiatan yang mengikuti pelatihan secara keseluruhan adalah 60% dari semua peserta pelatihan.</p><p> </p><p><strong><em><br /></em></strong></p><div id="gtx-trans" style="position: absolute; left: -73px; top: 416px;"> </div>
PENGEMBANGAN USAHA SAYURAN DAUN SINGKONG UNTUK PEMENUHAN KEBUTUHAN DAPUR UNIDA DAN RUMAH MAKAN PADANG BAGI UPT AGROTEKNOLOGI
Authors: Isnatin Umi , Etica Use 
Published: August 2021

<p><strong><em>Abstract</em></strong><em>. The Technical Implementation Unit of agrotechnology as an entrepreneurial development for the student of agrotechnology at the University of Darussalam Gontor has a problem at the managerial level. The management indicator referred to is cultivation management, finance, and marketing. Therefore, this research emphasizes the program on improving students' managerial abilities for 4 months. The purpose of this study is as a means of learning for students in cultivating cassava plants for entrepreneurship. One thing that must be improved is the cultivation of cassava leaves and how to market them. Furthermore, the availability of cassava leaves (Manihot utilisima) refers to the production of cassava plants, and up until this point, there is no special cultivation for cassava leaves. The method used in this research is the practice of cultivating cassava and holding training in making Bhokasi and POC fertilizers, training in making vegetable pesticides, training for post-harvest and product packaging. This service activity will help to succeed in improving student skills as well as practicing cassava cultivation and building marketing networks in the UNIDA Gontor's business units and Padang restaurant as one of the restaurants that use cassava leaves the most.</em></p><p> </p><p> </p><p><strong><em>Abstrak.</em></strong><em> UPT Agroteknologi sebagai lokasi pengembangan kewirausahaan mahasiswa prodi Agroteknologi Universitas Darussalam Gontor masih belum maksimal dalam pengelolaan. Indikator pengelolaan yang dimaksud adalah pengelolaan managemen budidaya, keuangan dan pemasaran. Pengabdian kami fokuskan pada program peningkatan kemampuan mahasiwa selama 4 bulan. Tujuan dari kegiatan ini sebagai sarana belajar mahasiswa dalam budidaya tanaman singkong yang akan diambil daunnya dan wirausaha. Salah satu yang akan kita tingkatkan adalah budidaya daun singkong dan cara pemasarannya. Daun singkong (Manihot utilisima), selama ini ketersediaannya mengacu kepada produksi tanaman singkong, dan belum ada budidaya khusus untuk sayur daun singkong. Adapun metode kegiatan yang kami lakukan adalah praktek budidaya tanaman singkong dan mengadakan pelatihan pembuatan pupuk Bhokasi dan POC, pelatihan pembuatan pestisida nabati, pelatihan pasca panen dan pengemasan produk. Kegiatan pengabdian ini berhasil peningkatkan kemampuan mahasiswa sekaligus praktek budidaya tanaman singkong dan membangun jaringan pemasaran di dapur UNIDA Gontor dan Rumah Makan Padang. .</em></p><p> </p><div id="gtx-trans" style="position: absolute; left: 174px; top: 481px;"> </div>
Firm Specific Capability Organisational Structure and New Product Performance of Fast Moving Consumer Goods Manufacturers in Emerging Economy
Authors: Abiodun B Onamusi , Tolulope E Adenekan , Elizabeth O Ojo , Olubukola A Owolabi 
Published: August 2021

Purpose: This study was centered on understanding the linkages between internal organizational competencies and performance of new products and the role of organizational structure focusing on Fast Moving Consumer Goods (FMCGs) manufacturers in the South-Western States in Nigeria.
Methodology: A survey approach was adopted, and 529 employees of fifteen FMCGs took part in data gathering. A moderated regression analysis was used to test the hypotheses formulated
Findings: The results of the moderated regression analysis established that firm-specific capability significantly enhanced new product performance, and the introduction of a definitive organizational structure increased the established effect firm-specific capability had on new product performance to suggest a significant moderator.
Implications: Management of the FMCGs investigated need to strengthen their commitment to developing critical and dynamic firm-specific capability and understand the relevance of organizational structure appropriateness. The firms should possess the knowledge to deploy ambidextrous firm-specific capability; it would enable the firms to expand and explore market opportunities that facilitate achieving significant new product performance.
Perancangan Intrusion Prevention System pada Jaringan Software Defined Networks
Authors: Nugroho Muhammad Arief , Suwastika Novian Anggis 
Published: August 2021

Keamanan jaringan telah menjadi bagian penting dalam implementasi di dalam jaringan Software Defined Network (SDN). Menyelenggarakan jaringan aman di dalam jaringan SDN merupakan tantangan tersendiri karena bagaimana sebuah perangkat jaringan dapat mampu mengenali, mengidentifikasi, dan mencegah serangan di level perangkat jaringan bukan di level host. Intrusion Prevention System (IPS) memberikan kemampuan untuk mengenali, mengidentifikasi, dan mencegah serangan yang terjadi secara otomatis. Integrasi IPS ke dalam jaringan SDN memberikan keuntungan bahwa administrator dapat mengatur dan memonitor keamanan jaringan secara terpusat. Dari hasil pengujian yang telah dilakukan, integrasi IPS ke dalam jaringan SDN mampu mendeteksi dan mencegah serangan yang terjadi dalam jaringan SDN sesuai dengan rule yang terdefinisi dalam IPS. Namun, terjadi penurunan kinerja throughput, delay, dan jitter di dalam jaringan SDN. Hal ini terjadi karena setiap paket yang melewati perangkat jaringan harus melewati proses pengecekan rule di dalam IPS.
Tantangan dan Isu-Isu E-Government Indonesia Dilihat dari Layanan untuk Masyarakat
Authors: Amalia Endang 
Published: August 2021

Setiap kementerian dan pemerintah daerah di Indonesia memiliki layanan terpisah untuk melayani warga. Tapi dengan kementerian e-government dan pemerintah daerah harus bisa lebih meningkatkan pelayanan publik bagi warga negara dan terpusat.
Dalam penelitian ini akan dianalisis mengenai tantangan dan permasalahan yang terjadi di Indonesia dari perspektif pelayanan bagi warga negara untuk menghindari ketidaknyamanan dan perihal yang tidak perlu dalam hal pindah, tinggal, belajar, bekerja, berbelanja atau sekadar bepergian ke luar negeri.
Kelompok layanan untuk warga yang dianalisis dalam penelitian ini adalah Travel, Work and Retirement, Vehicles, Residence formalities, Education and Youth, Health, Family konsumen yang dihasilkan dari penelitian ini dapat mengarahkan pemerintah untuk fokus pada peningkatan layanan publik bagi warga negara.