bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the Implementation of a Home-Based Exercise Training Program for People With COPD: A Mixed-Methods Study
Authors: Cerini Tamara , Kunz Ramona , Dalla Lana Kaba , Radtke Thomas , Polhemus Ashley , Puhan Milo A. , Frei Anja 
Published: October 2021

Introduction: Recently, we developed a home-based, minimal-equipment exercise training program HOMEX for people with chronic obstructive pulmonary disease (COPD) and tested its effectiveness over 1 year in a randomized controlled trial. The aims of the current study were to evaluate the implementation of HOMEX from the perspectives of all involved persons and to optimize the program to ensure its long-term sustainability.Methods: In this mixed-methods study, we used qualitative and quantitative approaches to evaluate the implementation of the intervention on the level of patients with COPD and coaches who provided the intervention and relevant stakeholders. To assess the implementation outcomes dose, reach, fidelity, and adherence, we summarized information recorded in the notes of the coaches and the diaries of patients, complemented with results from qualitative assessments. To assess acceptability and appropriateness, we conducted surveys with patients and coaches, and semistructured interviews with selected patients, coaches, and stakeholders.Results: The coaches delivered the three home visits with one exception according to the protocol (fidelity). Of the 53 intervention group participants, 37 (70%) conducted HOMEX training until the end of the study and 43 (79%) trained for at least 10 months. The exercise behaviors of the participants could be separated into the phases “Starting the training and stabilizing into regular training routine” and “Managing training disruptions” (adherence). Overall, patients, coaches, and stakeholders conveyed a very high “acceptability” of HOMEX, noting the home-based aspect as a particular strength and interaction with other patients as future need. All involved groups perceived the strength-training exercises as appropriate, efficient for people with COPD, and relevant to maintain improvements after pulmonary rehabilitation. The most important facilitators of the patients for long-term motivation were self-perceived improvement in strength, supervision by a coach, and integration of the training in daily routine. Based on these insights, we redesigned and reworded the exercise cards, introduced three new exercises, and refined the training book.Discussion: The results of this study provided insights of the involved persons in the frame of the HOMEX intervention implementation with a particular focus on the long-term training behavior of the participants and their perception and experience with the exercise program. These findings enabled us to optimize the training material and adapt the structure of the program for sustainable further use in clinical and other settings.
Management of Primary Squamous Cell Carcinoma of the Pancreas: A Case Report
Authors: Guo Danling , Chen Chao , Lv Sangying , Wu Guanzuan , Shi Wei , Li Huaifeng , Hu Hongjie 
Published: October 2021

Introduction: Primary squamous cell carcinoma of the pancreas (SCCP) is a rare malignant tumor that has been reported in individual case reports only. The clinical data on primary SCCP treatment are limited. Therefore, the appropriate management strategy for this disease should be standardized.Case Presentation: We present the case of a 63-year-old man admitted to our hospital for upper left abdominal pain for 2 months without weight loss or jaundice. Enhanced computed tomography (CT) and magnetic resonance imaging (MRI) of the abdomen revealed a mixed solid and cystic lesion in the pancreatic tail, measuring 35 × 37 mm in maximum diameter with enhancement. The patient was diagnosed with primary SCCP without metastasis, based on radiological and pathological findings. He did not receive neoadjuvant therapy postoperatively and was followed up by CT and MRI for 18 months without recurrence or metastasis.Result: Complete resection is the most effective treatment for early stage primary SCCP. Abdominal MRI is an effective imaging tool for preoperative evaluation and postoperative follow-up of primary SCCP. The need for neoadjuvant therapy depends on various factors.Conclusion: Primary SCCP is a tumor with poor prognosis. Risk factor control, early accurate radiologic evaluation, and individualized treatment strategies improve the quality of life and prolong the overall survival period of patients.
Syntaxin-1 and Insulinoma-Associated Protein 1 Expression in Breast Neoplasms with Neuroendocrine Features
Authors: Turkevi-Nagy Sándor , Báthori Ágnes , Böcz János , Krenács László , Cserni Gábor , Kővári Bence 
Published: October 2021

Introduction: A subset of breast neoplasia is characterized by features of neuroendocrine differentiation. Positivity for Neuroendocrine markers by immunohistochemistry is required for the diagnosis. Sensitivity and specificity of currently used markers are limited; based on the definitions of WHO Classification of Tumours, 5th edition, about 50% of breast tumors with features of neuroendocrine differentiation express chromogranin-A and 16% express synaptophysin. We assessed the applicability of two novel markers, syntaxin-1 and insulinoma-associated protein 1 (INSM1) in breast carcinomas.Methods: Hypercellular (Type B) mucinous carcinomas, solid papillary carcinomas, invasive carcinomas of no special type with neuroendocrine features and ductal carcinomas in situ of neuroendocrine subtype were included in our study. The immunohistochemical panel included chromogranin A, synaptophysin, CD56, syntaxin-1 and INSM1. The specificity of syntaxin-1 and INSM1 was determined using samples negative for chromogranin A, synaptophysin and CD56.Results: The sensitivity of syntaxin-1 was 84.7% (50/59), with diffuse positivity in more than 60% of the cases. Syntaxin-1 also had an excellent specificity (98.1%). Depending on the definition for positivity, the sensitivity of INSM1 was 89.8% (53/59) or 86.4% (51/59), its specificity being 57.4% or 88.9%. The sensitivities of chromogranin A, synaptophysin and CD56 were 98.3, 74.6 and 22.4%, respectively.Discussion: Syntaxin-1 and INSM1 are sensitive and specific markers of breast tumors with neuroendocrine features, outperforming chromogranin A and CD56. We recommend syntaxin-1 and INSM1 to be included in the routine neuroendocrine immunohistochemical panel.
Susceptibility of Field-Collected Nyssorhynchus darlingi to Plasmodium spp. in Western Amazonian Brazil
Authors: Alonso Diego Peres , Alvarez Marcus Vinicius Niz , Ribolla Paulo Eduardo Martins , Conn Jan E. , de Oliveira Tatiane Marques Porangaba , Sallum Maria Anice Mureb 
Published: October 2021

Mosquito susceptibility to Plasmodium spp. infection is of paramount importance for malaria occurrence and sustainable transmission. Therefore, understanding the genetic features underlying the mechanisms of susceptibility traits is pivotal to assessing malaria transmission dynamics in endemic areas. The aim of this study was to investigate the susceptibility of Nyssorhynchus darlingi—the dominant malaria vector in Brazil—to Plasmodium spp. using a reduced representation genome-sequencing protocol. The investigation was performed using a genome-wide association study (GWAS) to identify mosquito genes that are predicted to modulate the susceptibility of natural populations of the mosquito to Plasmodium infection. After applying the sequence alignment protocol, we generated the variant panel and filtered variants; leading to the detection of 202,837 SNPs in all specimens analyzed. The resulting panel was used to perform GWAS by comparing the pool of SNP variants present in Ny. darlingi infected with Plasmodium spp. with the pool obtained in field-collected mosquitoes with no evidence of infection by the parasite (all mosquitoes were tested separately using RT-PCR). The GWAS results for infection status showed two statistically significant variants adjacent to important genes that can be associated with susceptibility to Plasmodium infection: Cytochrome P450 (cyp450) and chitinase. This study provides relevant knowledge on malaria transmission dynamics by using a genomic approach to identify mosquito genes associated with susceptibility to Plasmodium infection in Ny. darlingi in western Amazonian Brazil.
Evaluation of Naïve Bayes and Chi-Square performance for Classification of Occupancy House
Authors: Wijaya Nurhadi 
Published: October 2021

Occupancy status is one indicator of the rehabilitation and reconstruction program to support eruption victims in Indonesia. It needs to establish the rehabilitation and reconstruction in digital system with structured database. In this paper, we provide dataset 2,146 occupied and 370 unoccupied houses. We utilize a naive Bayes classifier to classify the objects and implement a chi-square algorithm to measure comparison data to actual observed data. This research uses a combination of Naive Bayes and Chi-Square by applying weighting to the dataset attributes. Our study conclude that the combination of the algorithms can achieve a promosing result in classifying the occupancy houses status. The combination of the proposed technique gain 89.59% accuracy and ROC-AUC value 0.839. Therefore, our approach is better than the standard Naive Bayes without combination with the Chi-Square approach
IMPLEMENTATION OF THE COMSTOCK METHOD FOR ANDROID BASED PATIENT LEFTOVERS FOOD MANAGEMENT
Authors: Sundarina Lu'luil Maknun 
Published: October 2021

Nowadays, nutritionists should count manually to know how much nutrition that patients get as the development of technology, human work easier likewise in counting the patient's food waste so it will be more efficient and not waste a lot of time. This research aims to build an application that can facilitate nutritionists in the calculating amount of food waste by using the Comstock method. The system is designed to use Unified Modeling Language (UML) and programming language Hypertext Preprocessor (PHP) and Hyper Markup Language (HTML). The result of this research is in the form of application which could be used by nutritionists at hospital calculate the amount of food waste of patients using the android-based Comstock method at the hospital using the Comstock method.
ANALISIS SWOT PADA WEBSITE PINTER JAWA UNTUK MENENTUKAN PELUANG BELAJAR BUDAYA JAWA
Authors: Devita Ika Fahmasari Yuli Astuti, 
Published: October 2021

The state of Indonesian culture, especially Javanese culture is even more alarming. Frequency of use of the Java language within the family declined replaced by the use of Bahasa Indonesia. If left not impossible Java language will be extinct. Besides 75 kinds of puppets also already extinct. Given the situation we need a culture of learning media so that the public Java Indonesia still has knowledge of Javanese culture from extinction. Thus it was established as a Java Pinter Website Learning Media Javanese culture. Website Pinter system design in Java using the system flowchart and DFD and ERD database design using SWOT analysis as the analysis stage to find out opportunities and threats. Keywords: Javanese culture, opportunities, SWOT INTISARIKeadaan Budaya Indonesia khususnya budaya Jawa semakin memprihatinkan. Frekuensi pengguanaan Bahasa Jawa dalam lingkungan keluarga semakin menurun tergantikan oleh penggunaan Bahasa Indonesia. Jika dibiarkan bukan tidak mungkin Bahasa Jawa akan mengalami kepunahan. Selain itu 75 jenis wayang juga sudah mengalami kepunahan. Dengan adanya keadaan tersebut maka dibutuhkan suatu media pembelajaran budaya jawa agar masyarakat Indonesia tetap memiliki pengetahuan Budaya Jawa agar tidak punah. Maka dari itu dibuatlah Website Pinter Jawa ini sebagai Media Pembelajaran Budaya Jawa.Perancangan sistem pada Website Pinter Jawa menggunakan flowchart sistem dan DFD perancangan database menggunakan ERD dan analisis SWOT sebagai tahapan analisis untuk mengetahui peluang dan ancamannya. Kata Kunci: budaya jawa, peluang, SWOT
Sistem Informasi Manajemen Ruangan Berbasis Cloud Computing (Studi Kasus : Universitas Respati Yogyakarta)
Authors: Siswanto Lindung 
Published: October 2021

INTISARIRuangan dalam kaitan nya untuk kegiatan akademik di Universitas Respati Yogyakarta (UNRIYO) baik itu ruangan kuliah, laboratorium atau ruangan lain yang digunakan secara bersama merupakan sarana yang penting untuk mendukung kelancaran dalam kegiatan akademik. Kegiatan akademik yang diselenggarakan oleh dosen, mahasiswa dan unit kerja lain yang dilakukan di UNRIYO seringkali terjadi hambatan yang disebabkan keterbatasan ruangan, dan hal ini tidak tertangani dengan baik karena tidak adanya monitoring dan pengaturan terhadap penggunaan ruangan. Penelitian bertujuan untuk merancang dan membangun sistem informasi manajemen ruangan dengan metode pengembangan perangkat lunak dengan SDLC didukung dengan teknologi cloud computing sebagai penyedia infrastuktur dengan kemampuannya untuk bisa disesuaikan dengan kapasistas sistem yang akan dibangun, pemeliharaan yang mudah dengan biaya rendah sehingga kuaitas layanan sistem yang diberikan dapat terjaga dengan baik. Dari hasil penelitian diharapkan dapat membantu UNRIYO khususnya dosen, mahasiswa dan unit kerja yang bertanggung jawab terhadap pengelolaan ruangan untuk dapat memonitoring serta pemanfaatan ruangan secara baik dan maksimal. Kata kunci — Sistem informasi manajemen, pemesanan ruangan, akademik, iaas, cloud computing. ABSTRACTThe room in relation to academic activities at the University of Respati Yogyakarta (UNRIYO) whether lecture rooms, laboratories or other rooms that are used together is an important means to support fluency in academic activities. Academic activities organized by lecturers, students and other work units conducted at UNRIYO often occur due to limited space constraints, and this is not handled properly because there is no monitoring and regulation of room use.The research aims to design and build a room management information system with software development methods with SDLC supported by cloud computing technology as a provider of infrastructure with the ability to be adapted to the capacity of the system to be built, easy maintenance at low cost so that the quality of service systems provided can well maintained.The results of the study are expected to help UNRIYO especially lecturers, students and work units who are responsible for the management of the room to be able to monitor and use the space properly and optimally.Keywords — Management information systems, room reservations, academics, iaas, cloud computing.
Implementasi Teknik Steganografi Menggunakan Algoritma Transposisi Columnar
Authors: Salim Yeffriansjah 
Published: October 2021

INTISARIKerahasiaan data sangat diperlukan untuk menjaga dari pihak=pihak yang tidak berwenang agar tidak dapat mengaksesnya, untuk itu diperlukan teknik steganografi dan enkripsi untuk mengaburkan pesan yang dikirimkan ke dalam bentuk gambar / cover image. Tujuan utama penelitian ini adalah membuat aplikasi yang berguna memasukan teks / plain text yang akan dienkripsi menggunakan kata kunci / encryption key menjadi cypher text kemudian disisipkan ke dalam cover image menjadi stego object kemudian hasil dari stego object dipisahkan antara cypher text dan cover image, selanjutnya cypher text didekrip menggunakan kata kunci / encryption key untuk dapat menghasilkan teks sumber / plain text. Metode yang digunakan dalam penelitian ini adalah algoritma transposisi columnar dengan model transposisi 12-21. Hasil yang diperoleh dari penelitian ini membandingkan ukuran file dari gambar yang menjadi cover image, stego object, dan gambar hasil dari pemisahan cypher text dari stego object. Kesimpulan yang diperoleh ukuran file antara cover image dan stego object tidak mengalami perubahan yang signifikan berapapun jumlah ukuran teks yang disisipkan / hidden text ke cover image sehingga kriteria Steganografi yakni Fidelity, Robustness, dan Recovery terpenuhi dengan baik.Kata kunci — kriptografi, steganografi, cover image, Stego object, plain text, cypher text, encryption key dan transposisi columnar. ABSTRACTThe confidentiality of data is very necessary to protect the party from unauthorized parties so that they cannot access it, for this reason steganography and encryption techniques are needed to obscure the messages sent to them in the form of images. The main purpose of this research is to make an application that is useful to enter text / plain text that will be encrypted using the encryption key to be a cypher text and then inserted into the cover image into a stego object then the results of the stego object are separated between the Cypher text and cover image, then cypher Text is decrypted using an encryption key to produce plain text. The method used in this study is the columnar transposition algorithm with the transposition model 12-21. The results obtained from this study compare the file size of the image that is the cover image, stego object, and the image resulting from the separation of the cypher text from stego object. The conclusions obtained by the file size between the cover image and stego object did not change significantly regardless of the number of sizes of text inserted / hidden text to the cover image so that the Steganography criteria, namely Fidelity, Robustness, and Recovery were fulfilled well.Keywords - cryptography, steganography, cover image, Stego object, plain text, cypher text, encryption key and columnar transposition.
Implementasi Metode Inverse Kinematics Pada Gerakan Animasi 3D Karakter Manusia
Authors: Hanif Al Fatta Ahmad Zaid Rahman, Ema Utami, 
Published: October 2021

Perkembangan industri animasi saat ini, khususnya animasi digital yang dibuat pada umumnya sudah menggunakan bantuan dari komputer telah menjadi salah satu industri yang paling menguntungkan dengan angka pertumbuhan yang tinggi di setiap tahunnya. Model gerakan yang digunakan dalam proses animasi dapat dibuat dengan berbagai macam metode, salah satu metodenya adalah inverse kinematic. Metode ini diharapkan dapat menghasilkan gerak animasi yang lebih akurat. Penelitian ini menguji metode inverse kinematics dan diimplementasikan kedalam animasi 3D karakter manusia. Pada proses Pengujian akan dilakukan oleh animator professional dengan menganimasikan karakter 3 Dimensi yang sudah diberi parameter tolak ukur kebebasan tulang (Degrees of Freedom) dan menganimasikan karakter 3 Dimensi yang tidak menggunakan tolak ukur kebebasan tulang (Degrees of Freedom). Selanjutnya ditahap pengujian setelah dilakukan penganimasian pada karakter 3 Dimensi, yaitu membandingkan sudut yang terbentuk dari setiap sendi pada bagian tubuh animasi 3 Dimensi yang telah dibuat menggunakan metode inverse kinematic dengan video referensi yang berupa video live shoot. Pengujian ini penulis lakukan bertujuan untuk mengetahui berapa akurasi kemiripan dari kedua video tersebut. Software yang digunakan untuk mengukur sudut gerak sendi yaitu Tracker. Hasil dari penelitian ini ialah, untuk memberikan solusi agar pembuatan animasi 3D dapat lebih akurat dengan memperhatikan tolak ukur kebebasan tulang (Degrees of Freedom) sesuai anatomi pada manusia dan menggunakan metode inverse kinematics sehingga lebih akurat.Kata kunci—Animasi 3D, Gerakan, Inverse Kinematics, Rangka manusia, Sendi .
Analisis Perbandingan Kinerja Snort Dan Suricata Sebagai Intrusion Detection System Dalam Mendeteksi Serangan Syn Flood Pada Web Server Apache
Authors: Lukman Lukman , Suci Melati 
Published: October 2021

INTISARIKeamanan jaringan pada web server merupakan bagian yang paling penting untuk menjamin integritas dan layanan bagi pengguna. Web server sering kali menjadi target serangan yang mengakibatkan kerusakan data. Salah satunya serangan SYN Flood merupakan jenis serangan Denial of Service (DOS) yang memberikan permintaan SYN secara besar-besaran kepada web server.Untuk memperkuat keamanan jaringan web server penerapan Intrusion Detection System (IDS) digunakan untuk mendeteksi serangan, memantau dan menganalisa serangan pada web server. Software IDS yang sering digunakan yaitu IDS Snort dan IDS Suricata yang memiliki kelebihan dan kekurangannya masing-masing. Tujuan penelitian kali ini untuk membandingkan kedua IDS menggunakan sistem operasi linux dengan pengujian serangan menggunakan SYN Flood yang akan menyerang web server kemudian IDS Snort dan Suricata yang telah terpasang pada web server akan memberikan peringatan jika terjadi serangan. Dalam menentukan hasil perbandingan, digunakan parameter-parameter yang akan menjadi acuan yaitu jumlah serangan yang terdeteksi dan efektivitas deteksi serangan dari kedua IDS tersebut.Kata kunci: Keamanan jaringan, Web Server, IDS, SYN Flood, Snort, Suricata. ABSTRACTNetwork security on the web server is the most important part to guarantee the integrity and service for users. Web servers are often the target of attacks that result in data damage. One of them is the SYN Flood attack which is a type of Denial of Service (DOS) attack that gives a massive SYN request to the web server.To strengthen web server network security, the application of Intrusion Detection System (IDS) is used to detect attacks, monitor and analyze attacks on web servers. IDS software that is often used is IDS Snort and IDS Suricata which have their respective advantages and disadvantages.The purpose of this study is to compare the two IDS using the Linux operating system with testing the attack using SYN Flood which will attack the web server then IDS Snort and Suricata that have been installed on the web server will give a warning if an attack occurs. In determining the results of the comparison, the parameters used will be the reference, namely the number of attacks detected and the effectiveness of attack detection from the two IDS.Keywords: Network Security, Web Server, IDS, SYN Flood, Snort, Suricata.