bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding nurses’ experiences with near‐miss error reporting omissions in large hospitals
Authors: Lee Jaehee 
Published: March 2021

AbstractAimThis qualitative study aimed to provide an in‐depth understanding of nurses’ experiences with near‐miss errors and report omissions known to be direct or indirect causes of medical accidents in hospitals and cited as precursors of serious medical accidents.DesignThis study collected experiences of research participants through an interview as a qualitative research method and confirmed the meaning through an inductive approach.MethodsWe selected nine nurses with various levels of experience from 27 May to 10 June 2019 for analysis. We adopted phenomenological research methods and procedures proposed by Colaizzi (Existential‐phenomenological alternative for psychology, 1978) and established the feasibility and integrity of our results based on narrative studies proposed by Lincoln and Guba (Naturalistic inquiry, 1985).ResultsThis study demonstrated that near‐miss errors and report omissions experienced by professional nurses could be merged into the following themes: lack of cognitive susceptibility to near‐miss errors; confusion about the reporting system for near‐miss errors; lack of knowledge about near‐miss errors; disappointment with results of reporting near‐miss errors; and fear of reporting near‐miss errors. These results strongly suggest the need to improve recognition efforts based on a socio‐educational viewpoint involving the so‐called openness about failures.
Improving crosshole ground‐penetrating radar full‐waveform inversion results by using progressively expanded bandwidths of the data
Authors: Zhou Zhen , Klotzsche Anja , Vereecken Harry 
Published: March 2021

ABSTRACTIn the last decade, time‐domain crosshole ground‐penetrating radar full‐waveform inversion has been applied to several different test sites and has improved the resolution and reconstruction of subsurface properties. The full‐waveform inversion requires several diligent executed pre‐processing steps to guarantee a successful inversion and to minimize the risk of being trapped in a local minimum. Thereby, one important aspect is the starting models of the full‐waveform inversion. Generally, adequate starting models need to fulfil the half‐wavelength criterion, which means that the modelled data based on the starting models need to be within half of the wavelength of the measured data in the entire investigation area. Ray‐based approaches can provide such starting models, but in the presence of high contrast layers, such results do not always fulfil this criterion and need to be improved and updated. Therefore, precise and detailed data processing and a good understanding of experimental ground‐penetrating radar data are necessary to avoid erroneous full‐waveform inversion results. Here, we introduce a new approach, which improves the starting model problem and is able to enhance the reconstruction of the subsurface medium properties. The new approach tames the non‐linearity issue caused by high contrast complex media, by applying bandpass filters with different passband ranges during the inversion to the modelled and measured ground‐penetrating radar data. Thereby, these bandpass filters are considered for a certain number of iterations and are progressively expanded to the selected maximum frequency bandwidth. The resulting permittivity full‐waveform inversion model is applied to update the effective source wavelet and is used as an updated starting model in the full‐waveform inversion with the full bandwidth data. This full‐waveform inversion is able to enhance the reconstruction of the permittivity and electrical conductivity results in contrast to the standard full‐waveform inversion results. The new approach has been applied and tested on two synthetic case studies and an experimental data set. The field data were additionally compared with cone penetration test data for validation.
A survey of newly enrolled school psychology trainees: Estimates of key role and function
Authors: Weiner Yaacov , Shernoff Elisa S. , Kettler Ryan J. 
Published: March 2021

AbstractExamining school psychology trainees' perceptions regarding school psychologists' key role and function is important because inaccurate perceptions may lead to unmet professional expectations, reduced job satisfaction, and burnout. One hundred and eighty two first‐year school psychology graduate students enrolled in National Association of School Psychologists (NASP) approved and/or American Psychological Association accredited school psychology specialist and/or doctoral training programs were surveyed regarding their perceptions of how school psychologists spend their time. Responses were compared to results from the 2010 NASP survey of school psychologists, in which NASP members reported the percentage of time engaged in various school psychology functions. Respondents in the current sample underestimated time spent conducting special education evaluations t(399.54) = 12.2, p < 0.000, d = 0.76 and overestimated time spent providing individual student counseling, t(465.27) = 2.94, p < 0.001, d = 0.17 and student groups t(444.74) = 5.42, p < 0.001, d = 0.409, η2 = 0.04. A positive correlation between prior professional public school experience and time estimates for special education evaluations was found, r(175) = 0.14, p = 0.03. Implications for the field of school psychology are discussed, including the provision of updated information on key role and function to applicants along with screening to assess knowledge of the field.
Early childhood educators' beliefs about child behavior and adult outcomes related to gender and play
Authors: McCabe Paul C. 
Published: March 2021

AbstractThis study explored the beliefs of early childhood educators about a child's current behavior and potential adult adjustment based on a description of the child's gender and play interests. There were 451 early childhood educators from a US sample who, after reading a brief vignette describing a child's play and behavior, responded to questions related to the child's current and future behavior. Respondents also provided demographic information as well as ratings of their gender role beliefs. Results indicated that (a) educators believe strongly masculine or feminine play in early childhood predicts similar displays of masculinity or femininity in adulthood, (b) educator ratings of externalizing problem behaviors were significantly higher in the masculine play vignettes, irrespective of the child's gender, (c) ratings of internalizing problem behaviors were higher in the feminine play vignettes, also independent of child's gender, and (d) there were few differences in ratings between gender role conforming and gender role nonconforming children. However, the gender role nonconforming boy was rated as more likely to contemplate suicide as an adult compared to the gender role nonconforming girl and the gender role conforming boy and girl. Educators' beliefs about gender‐related constructs and recommendations for future practice and research were discussed.
Intergroup dialogue: A justice‐centered pedagogy to address gender inequity in STEM
Authors: White Brittany A. , Miles Joseph R. , Frantell Keri A. 
Published: March 2021

AbstractGender inequities in science, technology, engineering, and math (STEM) fields persist and calls have been made for continued efforts to challenge systemic sexism in STEM. In response to these calls, we examined the experiences of undergraduate and graduate STEM students who participated in an intergroup dialogue (IGD) focused on gender and sexism in STEM. We conceptualize IGD as a form of “justice‐centered” STEM pedagogy, designed to bring together individuals from different social identity groups with a history of tension between them (in this case, women and men in STEM) for sustained, face‐to‐face communication. The goals of the dialogue included (1) building relationships and understanding across genders, (2) developing a critical awareness of male privilege and systemic oppression (i.e., sexism), and (3) promoting capacities to work toward gender equity in STEM. The dialogue followed a modified version of an empirically validated model of IGD. Eight students participated in the IGD and post‐IGD interviews. Through grounded theory analyses of these interviews, four themes emerged including Barriers to Dialogue, Facilitative Factors, Cognitive and Attitudinal Outcomes, and Behavioral Outcomes. Ultimately, we engaged in theoretical integration around a core theme of perspective‐taking to characterize these young scientists' experiences in IGD. We explore the implications for STEM education and research and practice of IGD and conclude that IGD on gender, sexism, and intersecting forms of privilege and oppression in STEM has the potential to challenge inequitable cultures.
From Nanosecond Photochemistry to Optical Force Chemistry: My Journey
Authors: Masuhara Hiroshi 
Published: March 2021

AbstractLaser was invented in 1960 and soon introduced to chemistry research. We started time‐resolved spectroscopy and photochemistry and initial trial was focused to nanosecond and then picosecond electronic absorption spectroscopy for studying molecular electronic excited states, charge separation in molecular complexes, and intermolecular electron transfer in solution. We considered that not only time‐resolved but also space‐resolved chemistry would be important for future laser‐based chemistry and combined pulsed lasers with optical microscopes. Spectroscopy, photochemistry, ablation, and spatial arrangement of single microparticles and microdroplets in solution were carried out. Further we shifted from micro to nano and opened a new field covering spectroscopy, ablation, phase transition, crystallization, patterning, and fabrication. The progress is summarized and discussed as time‐resolved nano spectroscopy, ablation nano dynamics, and optical force chemistry.
Electrochemical Fluorescence Switch of Organic Fluorescent or Fluorogenic Molecules
Authors: Guille‐Collignon Manon , Delacotte Jérôme , Lemaître Frédéric , Labbé Eric , Buriez Olivier 
Published: March 2021

AbstractThis short review is aimed at emphasizing the most prominent recent works devoted to the fluorescence modulation of organic fluorescent or fluorogenic molecules by electrochemistry. This still expanding research field not only addresses the smart uses of known molecules or the design of new ones, but also investigates the development of instrumentation providing time‐ and space‐resolved information at the molecular level. Important considerations including fluorescent/fluorogenic probes, reversible/irreversible fluorescence switch, direct/indirect fluorescence modulation, or environment properties are especially scrutinized in recent works dealing with bioanalysis perspectives.
The short‐term and long‐term effects of Fe(II) on the performance of anammox granules
Authors: Zhou Biru , Chen Guangjiao , Dong Chifei , Jiang Yushi , Chen Haoyu , Ouyang Tong , Li Yu‐You , Zhang Yanlong 
Published: March 2021

AbstractFe(II) is one of the commonly used additives in wastewater treatment and proved to be beneficial for promoting microbial activity. In this study, the effects of Fe(II) on the specific anammox activity (SAA) and reactor performance were proved to be concentration‐dependent. In the short‐term experiment, low concentration of Fe(II) (5–80 mg/L) significantly enhanced the SAA, while high concentration of Fe(II) (120–300 mg/L) inhibited the SAA. It was confirmed that anammox can be domesticated after long‐term exposure to low Fe(II) concentration, and the SAA could be further enhanced by higher Fe(II) concentration in the following phases. In addition, as an important factor for anammox granulation and maintaining the SAA, the extracellular polymeric substance (EPS) was also affected by Fe(II) addition. In spite of the effects on SAA and EPS, Fe(II) was proved to be the key factor that enhances the N2O emission via abiotic pathway in the anammox reactor.Practitioner points

Low Fe(II) concentrations enhanced SAA, while high concentrations inhibited SAA.
Long‐term acclimatization by Fe(II) improved the tolerance of anammox to Fe(II).
Fe(II) affects the amount and constituent of EPS and the performance of anammox granules.
Accumulation of Fe(II) in the AAFEB reactor promoted the N2O emission.
Formen der Evidenzsynthese
Authors: Graf S. , Kranz J. , Schmidt S. , Bellut L. , Uhlig A. 
Published: March 2021

ZusammenfassungDer vorliegende Beitrag gibt einen Überblick über die verschiedenen Arten von Reviews (Übersichtsarbeiten) als Formen der Evidenzsynthese mit besonderem Hinblick auf deren Stärken sowie Limitationen. Reviews können Wissen in aggregierter Form beschreiben und erlauben zusätzlich eine Bewertung der Studienqualität eingeschlossener Arbeiten. Die Aussagekraft bzw. die Vertrauenswürdigkeit der Ergebnisse eines Reviews hängt stark von der Qualität der eingeschlossenen Daten ab, weswegen eine konsequente Auswahlstrategie notwendig ist. Ein Basiswissen zur Literaturbewertung und zu möglichen Verzerrungseffekten ist auch in der Betrachtung von Übersichtsarbeiten notwendig. Zu diesem Zweck werden in diesem Artikel auch ausgewählte Werkzeuge zur Evidenzbewertung und zur Beurteilung des Biasrisikos vorgestellt.
Knee position at the moment of bone bruise could reflect the late phase of non-contact anterior cruciate ligament injury rather than the mechanisms leading to ligament failure
Authors: Grassi Alberto , Agostinone Piero , Di Paolo Stefano , Lucidi Gian Andrea , Macchiarola Luca , Bontempi Marco , Marchiori Gregorio , Bragonzoni Laura , Zaffagnini Stefano 
Published: March 2021

Abstract
Purpose
The
aim of the present study was to trace knee position at the time of bone bruise (BB) and investigate how much this position departed from the knee biomechanics of an in vivo flexion–extension.

Methods
From an original cohort of 62 patients, seven (11%) presented bicompartmental edemas and were included in the study. 3D models of bones and BB were obtained from MRI. Matching bone edemas, a reconstruction of the knee at the moment of BB was obtained. For the same patients, knee kinematics of a squat was calculated using dynamic Roentgen sterephotogrammetric analysis (RSA). Data describing knee position at the moment of BB were compared to kinematics of the same knee extrapolated from RSA system.

Results
Knee positions at the moment of BB was significantly different from the kinematics of the squat. In particular, all the patients’ positions were out of squat range for both anterior and proximal tibial translation, varus–valgus rotation (five in valgus and two in varus), tibial internal–external rotation (all but one, five externally and one internally). A direct comparison at same flexion angle between knee at the moment of BB (average 46.1° ± 3.8°) and knee during squat confirmed that tibia in the former was significantly more anterior (p < 0.0001), more externally rotated (6.1 ± 3.7°, p = 0.04), and valgus (4.1 ± 2.4°, p = 0.03).

Conclusion
Knee position at the moment of Bone bruise position was out of physiological in-vivo knee range of motion and could reflect a locked anterior subluxation occurring in the late phase of ACL injury rather than the mechanism leading to ligament failure.

Level of evidence
Level IV
Checking for model failure and for prior-data conflict with the constrained multinomial model
Authors: Englert Berthold-Georg , Evans Michael , Jang Gun Ho , Ng Hui Khoon , Nott David , Seah Yi-Lin 
Published: March 2021

AbstractMultinomial models can be difficult to use when constraints are placed on the probabilities. An exact model checking procedure for such models is developed based on a uniform prior on the full multinomial model. For inference, a nonuniform prior can be used and a consistency theorem is proved concerning a check for prior-data conflict with the chosen prior. Applications are presented and a new elicitation methodology is developed for multinomial models with ordered probabilities.
Automated Western immunoblotting detection of anti-SARS-CoV-2 serum antibodies
Authors: Edouard Sophie , Jaafar Rita , Orain Nicolas , Parola Philippe , Colson Philippe , La Scola Bernard , Fournier Pierre-Edouard , Raoult Didier , Drancourt Michel 
Published: March 2021

AbstractELISA and chemiluminescence serological assays for COVID-19 are currently incorporating only one or two SARS-CoV-2 antigens. We developed an automated Western immunoblotting as a complementary serologic assay for COVID-19. The JessTM Simple Western system, an automated capillary-based assay, was used, incorporating an inactivated SARS-CoV-2 lineage 20a strain as the source of antigen, and total immunoglobulins (IgG, IgM, IgA) detection. In total, 602 sera were tested including 223 from RT-PCR-confirmed COVID-19 patients, 76 from patients diagnosed with seasonal HCoVs and 303 from coronavirus-negative control sera. We also compared this assay with the EUROIMMUN® SARS-CoV-2 IgG ELISA kit. Among 223 sera obtained from RT-PCR-confirmed COVID-19 patients, 180/223 (81%) exhibited reactivity against the nucleocapsid and 70/223 (31%) against the spike protein. Nucleocapsid reactivity was further detected in 9/76 (14%) samples collected from patients diagnosed with seasonal HCoVs and in 15/303 (5%) coronavirus-negative control samples. In the subset of sera collected more than 2 weeks after the onset of symptoms, the sensitivity was 94% and the specificity 93%, the latter value probably reflecting cross-reactivity of SARS-CoV-2 with other coronaviruses. The automated Western immunoblotting presented a substantial agreement (90%) with the compared ELISA (Cohen’s Kappa=0.64). Automated Western immunoblotting may be used as a second line test to monitor exposure of people to HCoVs including SARS-CoV-2.
Type IV collagen as a potential biomarker of metastatic breast cancer
Authors: Lindgren Moa , Jansson Malin , Tavelin Björn , Dirix Luc , Vermeulen Peter , Nyström Hanna 
Published: March 2021

AbstractNo reliable, non-invasive biomarker of metastatic breast cancer (mBC) exists: circulating CA15-3 (cCA15-3) is the marker mostly used to monitor mBC. Circulating collagen IV (cCOLIV) has been evaluated in other metastatic cancers and has been found to be a promising biomarker. The overarching aim of this study was to evaluate cCOLIV as a potential biomarker in patients with mBC. The first aim was to determine the levels of cCOL IV and cCA15-3 in patients with healthy controls, primary breast cancer (pBC) and mBC. The second aim was to compare levels of cCOLIV and cCA15-3 in patients with different metastatic sites of BC. The third aim was to investigate the prognostic value of cCOLIV and cCA15-3 for mBC patients. The fourth aim was to analyse whether a combination of the two biomarkers was more accurate in detecting mBC than a single marker. Lastly, we investigated the tissue expression levels of COLIV in BC bone metastases (BM) and liver metastases (LM). Plasma levels of cCOLIV and cCA15-3 from healthy controls and patients with pBC and mBC were measured. COLIV expression in tissue from patients with LM and BM was analysed using immunohistochemistry. Clinical and survival data were collected from medical charts. The levels of cCOLIV and cCA15-3 were significantly elevated in mBC patients compared with healthy controls and pBC patients. No differences in cCOLIV and cCA15-3 levels were found based on the metastatic site. High levels of cCOLIV, but not cCA15-3, correlated with poorer survival. cCOLIV alone and the combination of cCA15-3 and cCOLIV were superior to cCA15-3 at detecting mBC. COL IV was highly expressed in the tissue of LM and BM. Our study suggests that cCOLIV is a potential marker to monitor patients with BC.
Rare Pathogenic Variants in Mitochondrial and Inflammation-Associated Genes May Lead to Inflammatory Cardiomyopathy in Chagas Disease
Authors: Ouarhache Maryem , Marquet Sandrine , Frade Amanda Farage , Ferreira Ariela Mota , Ianni Barbara , Almeida Rafael Ribeiro , Nunes Joao Paulo Silva , Ferreira Ludmila Rodrigues Pinto , Rigaud Vagner Oliveira-Carvalho , Cândido Darlan , Mady Charles , Zaniratto Ricardo Costa Fernandes , Buck Paula , Torres Magali , Gallardo Frederic , Andrieux Pauline , Bydlowsky Sergio , Levy Debora , Abel Laurent , Cardoso Clareci Silva , Santos-Junior Omar Ribeiro , Oliveira Lea Campos , Oliveira Claudia Di Lorenzo , Nunes Maria Do Carmo , Cobat Aurelie , Kalil Jorge , Ribeiro Antonio Luiz , Sabino Ester Cerdeira , Cunha-Neto Edecio , Chevillard Christophe 
Published: March 2021

Abstract
Abstract
Cardiomyopathies are an important cause of heart failure and sudden cardiac death. Little is known about the role of rare genetic variants in inflammatory cardiomyopathy. Chronic Chagas disease cardiomyopathy (CCC) is an inflammatory cardiomyopathy prevalent in Latin America, developing in 30% of the 6 million patients chronically infected by the protozoan Trypanosoma cruzi, while 60% remain free of heart disease (asymptomatic (ASY)). The cytokine interferon-γ and mitochondrial dysfunction are known to play a major pathogenetic role. Chagas disease provides a unique model to probe for genetic variants involved in inflammatory cardiomyopathy.

Methods
We used whole exome sequencing to study nuclear families containing multiple cases of Chagas disease. We searched for rare pathogenic variants shared by all family members with CCC but absent in infected ASY siblings and in unrelated ASY.

Results
We identified heterozygous, pathogenic variants linked to CCC in all tested families on 22 distinct genes, from which 20 were mitochondrial or inflammation-related – most of the latter involved in proinflammatory cytokine production. Significantly, incubation with IFN-γ on a human cardiomyocyte line treated with an inhibitor of dihydroorotate dehydrogenase brequinar (enzyme showing a loss-of-function variant in one family) markedly reduced mitochondrial membrane potential (ΔψM), indicating mitochondrial dysfunction.

Conclusion
Mitochondrial dysfunction and inflammation may be genetically determined in CCC, driven by rare genetic variants. We hypothesize that CCC-linked genetic variants increase mitochondrial susceptibility to IFN-γ-induced damage in the myocardium, leading to the cardiomyopathy phenotype in Chagas disease. This mechanism may also be operative in other inflammatory cardiomyopathies.
Geochemical Variability of Surface Sediment in Post-Mining Lakes Located in the Muskau Arch (Poland) and Its Relation to Water Chemistry
Authors: Gąsiorowski Michał , Stienss Jacek , Sienkiewicz Elwira , Sekudewicz Ilona 
Published: March 2021

AbstractWater and sediment chemical compositions were investigated in 75 post-mining lakes in the eastern part of the Muskau Arch region (Western Poland, Central Europe). The lakes, originating from lignite and clay surfaces and underground mining activity, exhibited a wide gradient of physical and chemical water parameters. The most pronounced variability in water parameters was observed in pH values, conductivity, and oxygen concentration in the mixolimnion and monimolimnion. In addition, the lakes varied in terms of their trophic status, indicated by their dissolved organic carbon (DOC) and phosphorous concentrations. In general, lakes with higher pH values had higher trophic states, and some even exhibited hypertrophic conditions. The Monte Carlo test indicated that the water pH, phosphorus, DOC, and silicon concentrations could significantly explain the chemical characteristics of sediments.